# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- AglB_L1 PF18079.1 KXH24841.1 - 0.12 12.6 0.0 0.19 12.0 0.0 1.3 1 0 0 1 1 1 0 Archaeal glycosylation protein B long peripheral domain DUF5526 PF17664.1 KXH24841.1 - 0.19 11.3 0.0 0.25 10.9 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5526) UBA2_C PF16195.5 KXH24904.1 - 0.24 12.1 5.0 8.6 7.1 0.3 3.0 2 0 0 2 2 2 0 SUMO-activating enzyme subunit 2 C-terminus Velvet PF11754.8 KXH24905.1 - 4.5e-49 167.6 0.0 2.8e-31 109.4 0.0 3.9 2 2 1 3 3 3 2 Velvet factor Ras PF00071.22 KXH24976.1 - 1.4e-31 109.3 0.1 1.8e-31 108.9 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXH24976.1 - 4.2e-24 85.1 0.1 7.6e-24 84.2 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXH24976.1 - 1.3e-06 28.0 0.0 1.7e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KXH24976.1 - 0.00022 20.7 0.1 0.00029 20.3 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DLIC PF05783.11 KXH24976.1 - 0.0019 17.1 0.3 0.17 10.7 0.0 2.1 1 1 1 2 2 2 2 Dynein light intermediate chain (DLIC) DUF2070 PF09843.9 KXH24996.1 - 1.2 7.3 4.8 1.5 7.0 4.8 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) GIT_SHD PF08518.11 KXH24997.1 - 7.2e-23 79.9 5.7 2.4e-11 43.1 2.4 2.6 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT PSII_Pbs27 PF13326.6 KXH24997.1 - 0.0066 16.8 7.5 0.049 14.0 1.6 2.7 2 0 0 2 2 2 1 Photosystem II Pbs27 CLZ PF16526.5 KXH24997.1 - 0.013 15.8 2.0 0.013 15.8 2.0 3.8 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels FUSC PF04632.12 KXH24997.1 - 0.062 11.8 16.0 0.015 13.8 12.9 1.5 2 0 0 2 2 2 0 Fusaric acid resistance protein family Filament PF00038.21 KXH24997.1 - 0.09 12.4 30.8 0.036 13.7 8.0 2.6 2 1 0 2 2 2 0 Intermediate filament protein HetR_C PF18460.1 KXH24997.1 - 0.15 12.0 5.2 0.9 9.5 0.4 2.9 2 1 0 2 2 2 0 Heterocyst differentiation regulator C-terminal Hood domain UPF0242 PF06785.11 KXH24997.1 - 0.17 12.0 34.6 3.5 7.7 13.7 2.6 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Adhesin_P1_N PF18652.1 KXH24997.1 - 0.18 11.9 4.6 8 6.6 0.1 3.8 3 0 0 3 3 3 0 Adhesin P1 N-terminal domain OmpH PF03938.14 KXH24997.1 - 2 8.8 43.7 12 6.2 3.1 4.7 3 1 2 5 5 5 0 Outer membrane protein (OmpH-like) THP2 PF09432.10 KXH24997.1 - 2.5 8.1 12.6 0.19 11.8 4.8 2.6 1 1 2 3 3 3 0 Tho complex subunit THP2 DUF3958 PF13125.6 KXH24997.1 - 3.7 7.8 32.5 0.19 12.0 4.8 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3958) YabA PF06156.13 KXH24997.1 - 6.9 7.4 26.8 37 5.0 2.0 5.0 2 1 1 3 3 3 0 Initiation control protein YabA DUF3365 PF11845.8 KXH24997.1 - 8.2 6.7 6.9 3.1 8.1 2.0 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3365) PhyH PF05721.13 KXH25044.1 - 0.0081 16.4 0.0 0.0093 16.2 0.0 1.4 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) MDM31_MDM32 PF08118.11 KXH25062.1 - 2.6e-250 831.5 0.0 3.4e-250 831.2 0.0 1.1 1 0 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins KH_8 PF17903.1 KXH25063.1 - 0.00092 19.3 0.0 0.002 18.2 0.0 1.5 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 KXH25063.1 - 0.0037 17.1 0.8 0.0074 16.1 0.8 1.5 1 0 0 1 1 1 1 KH domain eIF-3_zeta PF05091.12 KXH25064.1 - 1.2e-201 671.3 0.0 1.4e-201 671.0 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF569 PF04601.13 KXH25064.1 - 0.077 12.7 0.0 0.18 11.5 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF569) NARG2_C PF10505.9 KXH25064.1 - 0.15 11.6 0.0 2.2 7.8 0.0 2.1 2 0 0 2 2 2 0 NMDA receptor-regulated gene protein 2 C-terminus bZIP_1 PF00170.21 KXH25065.1 - 3.2e-05 24.0 8.4 3.2e-05 24.0 8.4 1.9 3 0 0 3 3 3 1 bZIP transcription factor PAP1 PF08601.10 KXH25065.1 - 0.11 12.2 4.8 0.83 9.3 0.0 2.3 2 0 0 2 2 2 0 Transcription factor PAP1 bZIP_2 PF07716.15 KXH25065.1 - 1.1 9.4 11.0 7.2 6.8 11.0 2.2 1 1 0 1 1 1 0 Basic region leucine zipper Abhydrolase_1 PF00561.20 KXH25094.1 - 1.5e-22 80.5 0.0 4e-20 72.5 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXH25094.1 - 2.2e-15 56.6 0.0 3.6e-14 52.6 0.0 2.3 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KXH25094.1 - 1.5e-14 55.2 0.0 5.6e-14 53.3 0.0 2.0 2 1 0 2 2 2 1 Alpha/beta hydrolase family DUF915 PF06028.11 KXH25094.1 - 7.2e-07 28.8 0.0 1.5e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Esterase PF00756.20 KXH25094.1 - 2.3e-05 24.2 0.0 7.1e-05 22.6 0.0 1.8 2 0 0 2 2 2 1 Putative esterase Abhydrolase_3 PF07859.13 KXH25094.1 - 0.021 14.7 0.0 0.69 9.7 0.0 2.3 2 0 0 2 2 2 0 alpha/beta hydrolase fold Ser_hydrolase PF06821.13 KXH25094.1 - 0.022 14.6 0.0 0.046 13.6 0.0 1.5 1 0 0 1 1 1 0 Serine hydrolase Peptidase_S15 PF02129.18 KXH25094.1 - 0.033 13.8 0.0 43 3.6 0.0 3.0 3 0 0 3 3 3 0 X-Pro dipeptidyl-peptidase (S15 family) Chlorophyllase2 PF12740.7 KXH25094.1 - 0.035 13.0 0.0 0.062 12.2 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme Lipase_3 PF01764.25 KXH25094.1 - 0.054 13.4 0.0 0.097 12.5 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) LIDHydrolase PF10230.9 KXH25094.1 - 0.054 13.0 0.0 0.12 11.9 0.0 1.6 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Abhydrolase_5 PF12695.7 KXH25094.1 - 0.074 12.8 0.0 0.22 11.3 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase family Chlorophyllase PF07224.11 KXH25094.1 - 0.11 11.5 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Spo7 PF03907.13 KXH25095.1 - 6e-95 316.9 0.1 1.1e-94 316.1 0.1 1.4 1 0 0 1 1 1 1 Spo7-like protein tRNA-synt_2c PF01411.19 KXH25153.1 - 3.1e-210 699.4 0.0 3.1e-210 699.4 0.0 1.4 2 0 0 2 2 2 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 KXH25153.1 - 2.2e-17 62.9 0.3 6.7e-17 61.3 0.3 1.9 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 KXH25153.1 - 1.4e-11 44.9 3.6 1.4e-11 44.9 3.6 2.2 2 0 0 2 2 2 1 DHHA1 domain Mitoc_L55 PF09776.9 KXH25153.1 - 0.05 13.3 1.2 3.7 7.3 0.1 3.1 3 0 0 3 3 3 0 Mitochondrial ribosomal protein L55 ChaB PF06150.12 KXH25153.1 - 0.065 13.8 0.8 0.49 11.0 0.8 2.6 1 0 0 1 1 1 0 ChaB UBA_e1_thiolCys PF10585.9 KXH25153.1 - 0.21 11.5 8.2 0.18 11.7 1.6 2.6 2 1 0 2 2 2 0 Ubiquitin-activating enzyme active site MAD PF05557.13 KXH25154.1 - 0.045 12.1 4.2 0.071 11.5 4.2 1.3 1 0 0 1 1 1 0 Mitotic checkpoint protein CPSF73-100_C PF11718.8 KXH25154.1 - 0.2 11.2 1.0 0.24 10.9 1.0 1.2 1 0 0 1 1 1 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term FXR_C1 PF16096.5 KXH25154.1 - 1.2 9.4 8.6 0.16 12.2 2.1 2.4 2 0 0 2 2 2 0 Fragile X-related 1 protein C-terminal region 2 DUF4551 PF15087.6 KXH25154.1 - 4.7 5.9 8.3 7.4 5.3 8.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) DUF4597 PF15366.6 KXH25154.1 - 7 6.5 12.5 1.3 8.8 1.1 3.8 3 1 0 4 4 4 0 Domain of unknown function (DUF4597) RCR PF12273.8 KXH25155.1 - 1.9e-10 41.4 10.5 6.1e-10 39.8 10.5 1.8 1 1 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red TMEM154 PF15102.6 KXH25157.1 - 5.9e-05 23.0 0.0 0.029 14.3 0.0 2.4 2 0 0 2 2 2 1 TMEM154 protein family DUF3180 PF11377.8 KXH25157.1 - 0.00018 21.7 0.7 0.0082 16.3 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3180) DUF4381 PF14316.6 KXH25157.1 - 0.00019 21.7 0.6 0.072 13.3 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4381) EphA2_TM PF14575.6 KXH25157.1 - 0.00026 21.8 0.0 0.15 13.0 0.0 2.4 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain BatD PF13584.6 KXH25157.1 - 0.00073 18.5 0.0 0.007 15.2 0.1 1.9 2 0 0 2 2 2 1 Oxygen tolerance GT87 PF09594.10 KXH25157.1 - 0.0018 18.0 1.1 0.46 10.2 0.3 2.3 2 0 0 2 2 2 1 Glycosyltransferase family 87 MHYT PF03707.16 KXH25157.1 - 0.0021 18.2 1.8 1.1 9.5 0.2 2.6 2 0 0 2 2 2 2 Bacterial signalling protein N terminal repeat DUF202 PF02656.15 KXH25157.1 - 0.0029 18.0 0.2 0.78 10.2 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Phage_holin_3_6 PF07332.11 KXH25157.1 - 0.011 15.7 0.2 0.73 9.9 0.0 2.3 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III DUF4229 PF14012.6 KXH25157.1 - 0.031 14.4 1.6 0.048 13.8 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) Gram_pos_anchor PF00746.21 KXH25157.1 - 0.035 14.0 2.7 2.1 8.4 0.2 2.4 2 0 0 2 2 2 0 LPXTG cell wall anchor motif Syndecan PF01034.20 KXH25157.1 - 0.036 14.0 0.1 11 6.0 0.0 2.5 2 0 0 2 2 2 0 Syndecan domain Herpes_gE PF02480.16 KXH25157.1 - 0.038 12.7 0.1 0.19 10.5 0.1 1.9 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E DUF5305 PF17231.2 KXH25157.1 - 0.044 13.2 0.2 0.53 9.6 0.3 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5305) PTP_tm PF18861.1 KXH25157.1 - 0.044 13.8 0.7 4 7.4 0.0 2.3 2 0 0 2 2 2 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J LPG_synthase_TM PF03706.13 KXH25157.1 - 0.053 13.0 0.3 3.6 7.0 0.0 2.1 2 0 0 2 2 2 0 Lysylphosphatidylglycerol synthase TM region RCR PF12273.8 KXH25157.1 - 0.058 14.1 0.0 1.8 9.2 0.0 2.5 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red Nitrate_red_gam PF02665.14 KXH25157.1 - 0.058 12.9 0.6 4.2 6.8 0.0 2.2 2 0 0 2 2 2 0 Nitrate reductase gamma subunit stn_TNFRSF12A PF12191.8 KXH25157.1 - 0.075 13.2 0.3 0.34 11.1 0.0 2.2 3 0 0 3 3 2 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain RseC_MucC PF04246.12 KXH25157.1 - 0.077 12.9 0.1 12 5.8 0.0 2.2 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Adeno_E3_CR2 PF02439.15 KXH25157.1 - 0.1 12.3 0.2 3.5 7.5 0.1 2.4 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 LapA_dom PF06305.11 KXH25157.1 - 0.11 12.3 1.7 2.3 8.1 0.1 2.2 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain MLANA PF14991.6 KXH25157.1 - 0.13 12.5 0.0 3.1 8.1 0.0 2.4 2 0 0 2 2 2 0 Protein melan-A DUF4131 PF13567.6 KXH25157.1 - 0.15 11.7 0.0 10 5.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) CcmH PF03918.14 KXH25157.1 - 0.16 11.2 0.6 2.9 7.2 0.0 2.4 3 0 0 3 3 3 0 Cytochrome C biogenesis protein DUF3995 PF13160.6 KXH25157.1 - 0.22 11.9 2.5 3.9 7.8 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3995) TauE PF01925.19 KXH25157.1 - 0.34 10.5 3.9 4.7 6.8 0.1 2.1 2 0 0 2 2 2 0 Sulfite exporter TauE/SafE CcmD PF04995.14 KXH25157.1 - 2.8 8.1 5.1 16 5.7 0.4 2.3 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) SKG6 PF08693.10 KXH25157.1 - 4.9 6.6 12.1 3 7.3 1.6 2.9 3 0 0 3 3 3 0 Transmembrane alpha-helix domain MtrF PF09472.10 KXH25157.1 - 7 6.1 5.6 33 4.0 0.3 2.4 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) AAA_12 PF13087.6 KXH25158.1 - 2.3e-23 82.8 0.0 4e-23 82.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KXH25158.1 - 1.9e-15 57.4 0.0 3.5e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 KXH25158.1 - 0.0016 18.3 0.0 20 4.8 0.0 3.7 4 0 0 4 4 4 2 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.6 KXH25158.1 - 0.004 17.0 0.0 0.0098 15.7 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 KXH25158.1 - 0.0094 15.7 0.0 1.4 8.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 KXH25158.1 - 0.13 12.6 0.0 1.1 9.5 0.0 2.4 2 1 0 2 2 2 0 AAA domain zf-C2H2 PF00096.26 KXH25159.1 - 3.7e-06 27.1 23.7 0.036 14.5 0.9 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXH25159.1 - 0.00067 20.3 20.0 0.43 11.6 2.9 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-MYST PF17772.1 KXH25159.1 - 0.074 12.7 0.1 0.17 11.6 0.1 1.5 1 0 0 1 1 1 0 MYST family zinc finger domain FANCL_C PF11793.8 KXH25159.1 - 0.28 11.4 2.7 0.56 10.4 2.7 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain Syndecan PF01034.20 KXH25159.1 - 0.29 11.1 1.2 0.6 10.1 1.2 1.5 1 0 0 1 1 1 0 Syndecan domain zf-C2H2_6 PF13912.6 KXH25159.1 - 0.31 11.1 7.6 1.9 8.6 1.6 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger Sina PF03145.16 KXH25159.1 - 4.2 7.3 12.3 34 4.3 10.1 2.2 1 1 1 2 2 2 0 Seven in absentia protein family Rrp40_N PF18311.1 KXH25160.1 - 2.5e-17 62.6 1.5 2.5e-17 62.6 1.5 1.9 2 0 0 2 2 2 1 Exosome complex exonuclease Rrp40 N-terminal domain KH_6 PF15985.5 KXH25160.1 - 1e-16 61.0 0.2 2.4e-16 59.8 0.0 1.7 2 0 0 2 2 2 1 KH domain HSP70 PF00012.20 KXH25161.1 - 7.4e-78 262.2 6.9 1.1e-77 261.6 6.9 1.3 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KXH25161.1 - 1.1e-10 40.8 0.4 2.1e-10 40.0 0.4 1.4 1 0 0 1 1 1 1 MreB/Mbl protein PilM_2 PF11104.8 KXH25161.1 - 0.006 15.7 0.3 3.6 6.5 0.1 2.6 2 1 0 2 2 2 2 Type IV pilus assembly protein PilM; AAA_33 PF13671.6 KXH25161.1 - 0.14 12.3 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Porin_5 PF16930.5 KXH25312.1 - 0.049 12.1 0.5 0.056 11.9 0.5 1.0 1 0 0 1 1 1 0 Putative porin DUF3464 PF11947.8 KXH25312.1 - 0.07 12.9 0.7 0.075 12.8 0.7 1.1 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 TMEM223 PF14640.6 KXH25312.1 - 0.081 13.1 0.0 0.095 12.9 0.0 1.1 1 0 0 1 1 1 0 Transmembrane protein 223 Ald_Xan_dh_C2 PF02738.18 KXH25313.1 - 3e-205 682.9 0.0 4.2e-205 682.4 0.0 1.2 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.21 KXH25313.1 - 1e-47 162.0 0.0 2.4e-47 160.9 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.22 KXH25313.1 - 7.6e-33 113.2 0.1 1.6e-32 112.1 0.1 1.6 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain CO_deh_flav_C PF03450.17 KXH25313.1 - 1.4e-30 105.5 0.7 3.9e-30 104.1 0.1 2.2 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Fer2_2 PF01799.20 KXH25313.1 - 3.7e-30 103.8 0.0 7.7e-30 102.7 0.0 1.6 1 0 0 1 1 1 1 [2Fe-2S] binding domain Fer2 PF00111.27 KXH25313.1 - 7e-08 32.3 0.1 7e-08 32.3 0.1 2.2 3 0 0 3 3 3 1 2Fe-2S iron-sulfur cluster binding domain DUF218 PF02698.17 KXH25313.1 - 0.027 14.5 0.1 0.085 12.9 0.1 1.8 1 0 0 1 1 1 0 DUF218 domain Aldedh PF00171.22 KXH25314.1 - 6.5e-121 404.0 0.0 5.7e-100 335.0 0.1 2.0 2 0 0 2 2 2 2 Aldehyde dehydrogenase family LuxC PF05893.14 KXH25314.1 - 0.0025 16.9 1.3 0.01 14.9 1.3 1.9 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF5633 PF18656.1 KXH25314.1 - 0.16 11.9 0.5 0.33 10.9 0.5 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5633) Epimerase PF01370.21 KXH25315.1 - 1.7e-13 50.6 0.0 3.9e-13 49.4 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXH25315.1 - 5.3e-12 45.3 0.0 1.7e-11 43.7 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KXH25315.1 - 2.9e-08 33.8 0.1 8.1e-08 32.4 0.1 1.7 2 1 0 2 2 2 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KXH25315.1 - 5.2e-08 32.4 0.0 1.3e-06 27.8 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 KXH25315.1 - 0.0002 20.9 0.1 0.0021 17.5 0.0 2.0 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 KXH25315.1 - 0.00043 19.9 0.0 0.0013 18.3 0.0 1.7 2 0 0 2 2 2 1 NmrA-like family RmlD_sub_bind PF04321.17 KXH25315.1 - 0.034 13.2 0.0 0.053 12.6 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain adh_short PF00106.25 KXH25315.1 - 0.091 12.2 0.0 0.26 10.7 0.0 1.8 2 0 0 2 2 2 0 short chain dehydrogenase pPIWI_RE_REase PF18154.1 KXH25315.1 - 0.14 12.2 0.0 0.34 10.9 0.0 1.6 1 0 0 1 1 1 0 REase associating with pPIWI_RE ApbA PF02558.16 KXH25315.1 - 0.18 11.4 0.0 0.3 10.7 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Abhydrolase_6 PF12697.7 KXH25317.1 - 1.2e-14 55.4 1.4 1.4e-14 55.2 1.4 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 KXH25317.1 - 0.0087 15.8 0.1 0.016 15.0 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXH25317.1 - 0.0098 15.2 0.0 0.016 14.5 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_8 PF06259.12 KXH25317.1 - 0.026 14.2 0.7 0.055 13.1 0.6 1.6 1 1 1 2 2 2 0 Alpha/beta hydrolase MFS_1 PF07690.16 KXH25319.1 - 1.8e-32 112.7 31.4 1.8e-32 112.7 31.4 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH25319.1 - 1.2e-09 37.6 8.0 1.2e-09 37.6 8.0 2.9 2 2 1 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.13 KXH25319.1 - 0.0001 20.9 1.3 0.00016 20.2 1.3 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) HCMV_UL124 PF17609.2 KXH25319.1 - 0.13 12.5 0.0 0.37 11.0 0.0 1.7 1 0 0 1 1 1 0 Family of unknown function MFS_1 PF07690.16 KXH25320.1 - 2e-20 73.0 27.6 4.5e-20 71.9 27.8 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily DIOX_N PF14226.6 KXH25321.1 - 3e-17 63.5 0.0 1.3e-16 61.4 0.0 2.0 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KXH25321.1 - 2.7e-11 43.8 0.0 4.6e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Ank_2 PF12796.7 KXH25322.1 - 2.3e-24 85.8 4.3 8.1e-07 29.5 0.4 5.1 2 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXH25322.1 - 4.5e-17 62.2 0.1 9.9e-05 22.8 0.0 5.3 5 0 0 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXH25322.1 - 9.9e-14 50.1 0.1 0.0013 19.1 0.0 7.2 8 0 0 8 8 8 2 Ankyrin repeat Ank_5 PF13857.6 KXH25322.1 - 1.7e-10 41.0 0.1 0.00061 20.0 0.0 4.7 6 1 0 6 6 6 2 Ankyrin repeats (many copies) Ank PF00023.30 KXH25322.1 - 2.3e-10 40.4 0.1 1 10.0 0.0 5.9 5 1 0 5 5 5 3 Ankyrin repeat Cu-oxidase_2 PF07731.14 KXH25324.1 - 2e-28 98.8 5.2 1.5e-26 92.8 2.6 2.6 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 KXH25324.1 - 4.7e-19 68.5 0.8 1.9e-18 66.6 0.1 2.2 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.22 KXH25324.1 - 3.8e-07 30.3 0.0 2.1e-05 24.7 0.0 3.2 3 0 0 3 3 3 1 Multicopper oxidase BORA_N PF15280.6 KXH25324.1 - 0.017 14.8 5.0 0.028 14.1 5.0 1.2 1 0 0 1 1 1 0 Protein aurora borealis N-terminus Macoilin PF09726.9 KXH25324.1 - 0.23 10.0 7.2 0.32 9.5 7.2 1.1 1 0 0 1 1 1 0 Macoilin family Flu_NP PF00506.18 KXH25326.1 - 0.096 11.3 0.0 0.13 10.8 0.0 1.1 1 0 0 1 1 1 0 Influenza virus nucleoprotein Phage_B PF02304.15 KXH25326.1 - 0.13 12.6 0.1 0.27 11.6 0.1 1.4 1 0 0 1 1 1 0 Scaffold protein B DUF1678 PF07913.11 KXH25327.1 - 0.015 15.1 0.0 0.016 15.0 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1678) NmrA PF05368.13 KXH25367.1 - 1.4e-63 214.6 0.0 1.6e-63 214.4 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXH25367.1 - 4.6e-17 62.5 0.0 6.7e-17 62.0 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KXH25367.1 - 4.5e-07 29.2 0.0 7.1e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KXH25367.1 - 0.00053 19.5 0.1 0.00094 18.7 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 KXH25367.1 - 0.039 14.2 0.1 0.096 12.9 0.1 1.6 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Melibiase PF02065.18 KXH25367.1 - 0.094 11.7 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Melibiase p450 PF00067.22 KXH25374.1 - 2.8e-22 79.1 0.0 3e-22 79.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Nop14 PF04147.12 KXH25384.1 - 0.15 10.3 8.3 0.31 9.2 8.3 1.4 1 0 0 1 1 1 0 Nop14-like family CBM-like PF14683.6 KXH25385.1 - 1.4e-30 106.3 0.0 3.4e-30 105.1 0.0 1.7 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.6 KXH25385.1 - 5.5e-09 35.7 0.3 2e-08 33.9 0.3 2.0 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.6 KXH25385.1 - 2.5e-07 30.9 2.5 0.00017 21.8 0.3 3.1 3 0 0 3 3 3 2 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 KXH25385.1 - 0.16 12.0 0.0 24 5.0 0.0 3.2 2 1 0 2 2 2 0 CarboxypepD_reg-like domain Fungal_trans PF04082.18 KXH25387.1 - 4.7e-09 35.7 0.1 4.7e-09 35.7 0.1 2.0 3 0 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH25387.1 - 0.0023 18.0 8.0 0.0042 17.2 8.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TFIIA PF03153.13 KXH25387.1 - 4.6 7.1 23.1 12 5.7 23.1 1.7 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit HEAT PF02985.22 KXH25388.1 - 4e-14 51.5 14.4 0.0034 17.5 0.0 9.8 11 0 0 11 11 9 2 HEAT repeat HEAT_EZ PF13513.6 KXH25388.1 - 4.5e-11 43.0 9.0 1.6e-07 31.7 0.0 7.0 9 0 0 9 9 7 1 HEAT-like repeat IBN_N PF03810.19 KXH25388.1 - 1.3e-10 41.1 3.5 1.3e-08 34.7 0.8 4.1 3 0 0 3 3 3 1 Importin-beta N-terminal domain HEAT_2 PF13646.6 KXH25388.1 - 1.3e-07 31.9 11.8 0.0051 17.2 0.2 6.6 4 2 3 7 7 7 3 HEAT repeats MMS19_C PF12460.8 KXH25388.1 - 1.5e-06 27.6 3.2 2.9e-06 26.7 0.4 2.5 2 1 0 2 2 2 1 RNAPII transcription regulator C-terminal CLASP_N PF12348.8 KXH25388.1 - 1.2e-05 25.0 0.6 0.96 9.0 0.1 4.6 2 2 2 4 4 4 2 CLASP N terminal DRIM PF07539.12 KXH25388.1 - 0.0016 16.9 2.5 2.9 6.1 0.4 4.3 2 1 0 4 4 4 1 Down-regulated in metastasis DUF3385 PF11865.8 KXH25388.1 - 0.002 18.0 1.9 4.7 7.1 0.4 4.7 4 2 1 5 5 5 1 Domain of unknown function (DUF3385) Arm PF00514.23 KXH25388.1 - 0.0025 17.8 0.4 38 4.5 0.0 5.7 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat DUF3347 PF11827.8 KXH25388.1 - 0.056 13.6 1.3 0.11 12.7 1.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) HEAT_PBS PF03130.16 KXH25388.1 - 0.077 13.7 0.0 53 4.9 0.0 4.9 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat Cse1 PF08506.10 KXH25388.1 - 0.11 11.3 0.1 1.7 7.4 0.0 2.9 2 1 1 3 3 3 0 Cse1 HMGL-like PF00682.19 KXH25389.1 - 6.1e-80 268.6 0.0 8.9e-80 268.0 0.0 1.2 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 KXH25389.1 - 1.8e-23 82.9 0.0 3.6e-23 81.9 0.0 1.6 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain Ferric_reduct PF01794.19 KXH25390.1 - 5e-23 81.6 11.2 5e-23 81.6 11.2 2.2 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KXH25390.1 - 2.9e-17 63.2 0.0 3.8e-15 56.3 0.0 2.4 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KXH25390.1 - 1.7e-09 37.7 0.0 4.6e-07 29.9 0.0 2.5 1 1 0 1 1 1 1 FAD-binding domain DUF1690 PF07956.11 KXH25392.1 - 2.1e-41 141.6 5.8 2.5e-41 141.3 5.8 1.0 1 0 0 1 1 1 1 Protein of Unknown function (DUF1690) cwf21 PF08312.12 KXH25392.1 - 0.0039 17.3 0.4 0.015 15.5 0.4 2.0 1 1 1 2 2 2 1 cwf21 domain Lebercilin PF15619.6 KXH25392.1 - 0.0055 16.4 9.9 0.0068 16.1 9.9 1.1 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease DUF842 PF05811.13 KXH25392.1 - 0.064 13.0 0.5 0.11 12.2 0.5 1.5 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) TLE_N PF03920.15 KXH25392.1 - 0.083 13.0 1.4 0.13 12.4 0.9 1.6 1 1 0 1 1 1 0 Groucho/TLE N-terminal Q-rich domain ALMT PF11744.8 KXH25392.1 - 0.13 11.1 0.8 0.15 10.9 0.8 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter GvpL_GvpF PF06386.11 KXH25392.1 - 0.53 10.2 8.3 0.19 11.7 6.0 1.3 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF FUSC PF04632.12 KXH25392.1 - 0.82 8.1 5.1 0.96 7.9 5.1 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family TYW3 PF02676.14 KXH25393.1 - 1.2e-75 253.5 0.0 1.6e-75 253.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase TYW3 IATP PF04568.12 KXH25393.1 - 0.093 13.2 0.3 0.093 13.2 0.3 2.2 3 0 0 3 3 3 0 Mitochondrial ATPase inhibitor, IATP PAPS_reduct PF01507.19 KXH25394.1 - 7.4e-44 149.8 0.2 1.8e-43 148.6 0.0 1.7 2 0 0 2 2 2 1 Phosphoadenosine phosphosulfate reductase family HAD PF12710.7 KXH25395.1 - 7e-20 72.2 0.1 9.7e-20 71.8 0.1 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KXH25395.1 - 1.7e-13 51.4 1.4 4.2e-13 50.1 1.4 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KXH25395.1 - 1.9e-08 34.4 0.5 1.4e-07 31.6 0.1 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KXH25395.1 - 0.0079 16.3 0.5 1.8 8.6 0.0 2.7 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase DUF705 PF05152.12 KXH25395.1 - 0.019 14.4 0.0 0.029 13.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF705) Put_Phosphatase PF06888.12 KXH25395.1 - 0.042 13.3 0.0 3.2 7.1 0.0 2.2 2 0 0 2 2 2 0 Putative Phosphatase DHHC PF01529.20 KXH25397.1 - 5.9e-36 123.5 5.6 5.9e-36 123.5 5.6 1.8 2 0 0 2 2 2 1 DHHC palmitoyltransferase Yip1 PF04893.17 KXH25397.1 - 0.0015 18.3 3.7 0.013 15.2 0.1 2.2 2 0 0 2 2 2 2 Yip1 domain Presenilin PF01080.17 KXH25398.1 - 0.13 11.0 2.3 0.15 10.8 2.3 1.1 1 0 0 1 1 1 0 Presenilin Zip PF02535.22 KXH25398.1 - 0.36 10.0 0.6 0.43 9.7 0.6 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF4698 PF15769.5 KXH25398.1 - 1 8.4 6.2 1.3 8.0 6.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4698) DDRGK PF09756.9 KXH25398.1 - 1.3 8.6 14.1 1.8 8.1 14.1 1.2 1 0 0 1 1 1 0 DDRGK domain Clr5 PF14420.6 KXH25399.1 - 8.8e-18 64.3 4.4 2.5e-17 62.9 4.4 1.8 1 0 0 1 1 1 1 Clr5 domain Peptidase_M4 PF01447.18 KXH25399.1 - 0.037 14.5 0.0 0.06 13.8 0.0 1.3 1 0 0 1 1 1 0 Thermolysin metallopeptidase, catalytic domain DUF386 PF04074.12 KXH25399.1 - 0.093 12.6 0.0 0.29 11.0 0.0 1.9 2 0 0 2 2 2 0 YhcH/YjgK/YiaL HET PF06985.11 KXH25400.1 - 1.9e-28 99.7 0.0 2.8e-28 99.1 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Fungal_trans PF04082.18 KXH25401.1 - 1.2e-12 47.4 0.0 2e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain PhyH PF05721.13 KXH25402.1 - 7.9e-19 68.8 0.0 1.1e-18 68.2 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Glyco_hydro_28 PF00295.17 KXH25404.1 - 6.4e-49 166.8 5.7 8.8e-49 166.3 5.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 FAD_binding_4 PF01565.23 KXH25405.1 - 2.1e-19 69.6 2.0 5e-19 68.4 2.0 1.7 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KXH25405.1 - 0.0061 16.6 0.1 0.014 15.5 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like FMN_dh PF01070.18 KXH25405.1 - 0.057 12.4 0.2 0.087 11.8 0.2 1.3 1 0 0 1 1 1 0 FMN-dependent dehydrogenase FMN_bind_2 PF04299.12 KXH25406.1 - 7.4e-57 191.7 0.0 8.7e-57 191.5 0.0 1.1 1 0 0 1 1 1 1 Putative FMN-binding domain EthD PF07110.11 KXH25407.1 - 1.1e-19 71.3 0.7 1.7e-19 70.8 0.7 1.3 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 KXH25407.1 - 1e-06 29.2 0.1 1.5e-06 28.6 0.1 1.2 1 0 0 1 1 1 1 Methylmuconolactone methyl-isomerase MFS_1 PF07690.16 KXH25408.1 - 8.3e-31 107.2 34.9 8.3e-31 107.2 34.9 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily F-box-like PF12937.7 KXH25409.1 - 0.00045 20.1 0.1 0.0012 18.6 0.1 1.8 1 0 0 1 1 1 1 F-box-like YqjK PF13997.6 KXH25409.1 - 0.051 13.8 0.7 0.12 12.6 0.7 1.6 1 0 0 1 1 1 0 YqjK-like protein Ferric_reduct PF01794.19 KXH25410.1 - 1.1e-18 67.5 4.7 1.1e-18 67.5 4.7 2.3 3 0 0 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KXH25410.1 - 7.5e-14 52.1 0.0 1.8e-12 47.7 0.0 2.4 2 1 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KXH25410.1 - 3.8e-13 49.5 0.1 3.3e-12 46.5 0.0 2.3 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_1 PF00175.21 KXH25410.1 - 0.0003 21.4 0.0 0.16 12.6 0.0 2.6 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain RepB PF07506.11 KXH25411.1 - 0.019 15.0 0.9 0.026 14.6 0.9 1.1 1 0 0 1 1 1 0 RepB plasmid partitioning protein GFA PF04828.14 KXH25412.1 - 5.2e-22 78.0 1.3 4.1e-19 68.7 1.3 2.3 1 1 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme ADH_N PF08240.12 KXH25413.1 - 2.3e-18 66.0 0.2 6.4e-18 64.6 0.2 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXH25413.1 - 4e-09 36.5 0.5 2.3e-06 27.6 0.1 3.0 2 1 0 2 2 2 2 Zinc-binding dehydrogenase HI0933_like PF03486.14 KXH25413.1 - 0.00037 19.3 0.2 0.0005 18.9 0.2 1.1 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.14 KXH25413.1 - 0.1 11.8 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KXH25413.1 - 0.13 11.5 0.1 0.2 11.0 0.1 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DUF423 PF04241.15 KXH25414.1 - 2.4e-23 82.1 1.0 5.2e-23 81.0 1.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF423) Bax1-I PF01027.20 KXH25414.1 - 0.0075 16.1 1.6 0.0087 15.9 1.6 1.1 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 p450 PF00067.22 KXH25415.1 - 6.2e-67 226.3 0.0 7.1e-67 226.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Trp_DMAT PF11991.8 KXH25416.1 - 8.2e-97 324.9 0.0 1e-96 324.6 0.0 1.1 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase UDPGT PF00201.18 KXH25417.1 - 1.8e-17 63.3 0.0 3.8e-15 55.7 0.0 2.2 2 0 0 2 2 2 2 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_transf_28 PF03033.20 KXH25417.1 - 0.00011 22.2 0.0 0.00025 21.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain Glyco_transf_4 PF13439.6 KXH25417.1 - 0.0036 17.3 0.2 0.012 15.6 0.2 1.8 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 KXH25417.1 - 0.019 15.4 2.7 0.15 12.5 2.6 2.3 1 1 0 1 1 1 0 Glycosyl transferase 4-like domain Epimerase_2 PF02350.19 KXH25417.1 - 0.02 13.7 0.0 0.11 11.4 0.0 2.0 2 0 0 2 2 2 0 UDP-N-acetylglucosamine 2-epimerase Glyco_tran_28_C PF04101.16 KXH25417.1 - 0.039 13.9 0.0 0.063 13.3 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain adh_short_C2 PF13561.6 KXH25417.1 - 0.14 11.7 3.6 1.3 8.6 0.8 2.3 2 0 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase Sulfotransfer_4 PF17784.1 KXH25418.1 - 7.1e-51 173.1 0.0 8.3e-51 172.9 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Ribonuc_L-PSP PF01042.21 KXH25419.1 - 5.1e-12 45.9 0.0 6.6e-12 45.5 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP WXG100 PF06013.12 KXH25419.1 - 0.0042 17.3 0.2 0.017 15.3 0.2 1.8 2 0 0 2 2 2 1 Proteins of 100 residues with WXG Sulfotransfer_4 PF17784.1 KXH25420.1 - 6.3e-56 189.6 0.7 9.9e-56 188.9 0.7 1.3 1 1 0 1 1 1 1 Sulfotransferase domain GAS2 PF02187.17 KXH25420.1 - 0.14 12.3 0.1 0.25 11.5 0.1 1.5 1 1 0 1 1 1 0 Growth-Arrest-Specific Protein 2 Domain Exo_endo_phos PF03372.23 KXH25421.1 - 3.6e-06 26.7 0.1 7.4e-06 25.6 0.1 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family HET PF06985.11 KXH25422.1 - 6.2e-09 36.4 0.3 4.4e-06 27.1 0.0 2.9 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) RNase_II_C_S1 PF18614.1 KXH25423.1 - 0.13 12.2 1.8 3.3 7.7 0.1 4.1 3 0 0 3 3 3 0 RNase II-type exonuclease C-terminal S1 domain SCP1201-deam PF14428.6 KXH25424.1 - 0.12 12.3 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 SCP1.201-like deaminase Abhydrolase_1 PF00561.20 KXH25425.1 - 1.1e-22 80.9 0.2 1.1e-21 77.6 0.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXH25425.1 - 1.8e-16 61.5 3.3 2.9e-16 60.8 3.3 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXH25425.1 - 7.9e-10 38.4 0.1 1.1e-09 37.9 0.1 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 KXH25425.1 - 0.0069 15.1 0.0 0.0092 14.7 0.0 1.1 1 0 0 1 1 1 1 Ndr family EHN PF06441.12 KXH25425.1 - 0.025 14.9 0.0 0.051 14.0 0.0 1.5 1 0 0 1 1 1 0 Epoxide hydrolase N terminus DUF1057 PF06342.12 KXH25425.1 - 0.26 10.3 0.0 0.33 9.9 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) RNase_PH PF01138.21 KXH25426.1 - 7.2e-15 55.7 0.0 2e-14 54.2 0.0 1.8 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KXH25426.1 - 0.039 14.0 0.0 0.068 13.2 0.0 1.4 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 eIF-3_zeta PF05091.12 KXH25427.1 - 0.051 12.6 0.1 0.057 12.4 0.1 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) GDI PF00996.18 KXH25428.1 - 1.6e-25 89.6 0.0 6.8e-13 47.9 0.0 2.1 1 1 1 2 2 2 2 GDP dissociation inhibitor Rad21_Rec8_N PF04825.13 KXH25429.1 - 1.4e-22 80.0 0.0 2.3e-22 79.2 0.0 1.3 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 KXH25429.1 - 2.9e-07 29.7 0.0 6.6e-07 28.5 0.0 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein IMD PF08397.11 KXH25431.1 - 2.2e-06 27.2 2.0 0.0017 17.7 0.4 2.3 2 0 0 2 2 2 2 IRSp53/MIM homology domain Abhydrolase_2 PF02230.16 KXH25432.1 - 6.6e-57 192.8 0.0 4.7e-34 118.1 0.0 2.1 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 KXH25432.1 - 8.5e-06 25.2 0.3 0.01 15.1 0.0 3.1 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KXH25432.1 - 0.0026 17.3 0.2 0.077 12.5 0.0 2.8 4 0 0 4 4 4 1 Prolyl oligopeptidase family FSH1 PF03959.13 KXH25432.1 - 0.01 15.5 0.0 0.14 11.8 0.0 2.5 2 1 0 2 2 2 0 Serine hydrolase (FSH1) DLH PF01738.18 KXH25432.1 - 0.041 13.4 0.0 0.077 12.5 0.0 1.5 1 0 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 KXH25432.1 - 0.083 12.7 1.0 0.64 9.8 0.1 2.6 2 1 1 3 3 3 0 alpha/beta hydrolase fold DUF2974 PF11187.8 KXH25432.1 - 0.11 12.0 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Lipase_3 PF01764.25 KXH25432.1 - 0.14 12.0 0.0 0.35 10.7 0.0 1.7 2 0 0 2 2 2 0 Lipase (class 3) Cutinase PF01083.22 KXH25432.1 - 0.21 11.5 0.0 0.36 10.8 0.0 1.4 1 0 0 1 1 1 0 Cutinase LigB PF02900.18 KXH25433.1 - 8e-28 97.3 0.0 1.1e-27 96.8 0.0 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Tudor_3 PF18115.1 KXH25433.1 - 0.12 12.3 0.3 19 5.2 0.0 2.4 2 0 0 2 2 2 0 DNA repair protein Crb2 Tudor domain TPR_11 PF13414.6 KXH25433.1 - 0.15 11.8 0.0 0.34 10.6 0.0 1.6 1 0 0 1 1 1 0 TPR repeat Peptidase_S8 PF00082.22 KXH25434.1 - 3.8e-37 128.2 9.4 7.3e-37 127.2 9.4 1.4 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 KXH25434.1 - 9.9e-22 77.4 0.5 2.6e-21 76.1 0.5 1.8 1 0 0 1 1 1 1 Peptidase inhibitor I9 Beach PF02138.18 KXH25436.1 - 8.9e-120 399.2 0.0 1.5e-119 398.5 0.0 1.4 1 0 0 1 1 1 1 Beige/BEACH domain Laminin_G_3 PF13385.6 KXH25436.1 - 6.6e-11 42.6 0.0 1.4e-10 41.6 0.0 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily PH_BEACH PF14844.6 KXH25436.1 - 3.4e-10 39.9 0.0 8.1e-10 38.7 0.0 1.6 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH WD40 PF00400.32 KXH25436.1 - 0.00027 21.7 4.1 0.14 13.1 0.1 4.7 4 0 0 4 4 4 1 WD domain, G-beta repeat DUF4704 PF15787.5 KXH25436.1 - 0.06 12.6 0.3 0.14 11.3 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4704) DUF4800 PF16057.5 KXH25436.1 - 0.1 11.9 0.2 0.25 10.6 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4800) DDOST_48kD PF03345.14 KXH25438.1 - 3.7e-168 559.7 0.0 4.2e-168 559.5 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta NAPRTase_C PF17956.1 KXH25438.1 - 0.13 12.7 0.0 0.25 11.8 0.0 1.5 1 0 0 1 1 1 0 Nicotinate phosphoribosyltransferase C-terminal domain PTS_2-RNA PF01885.16 KXH25512.1 - 1.4e-62 211.0 0.0 1.7e-62 210.7 0.0 1.0 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family FoP_duplication PF13865.6 KXH25512.1 - 0.33 11.5 11.7 0.71 10.5 11.7 1.5 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 MFS_1 PF07690.16 KXH25515.1 - 1.9e-18 66.5 7.0 2.7e-18 66.0 5.4 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF2834 PF11196.8 KXH25515.1 - 0.41 11.0 3.5 0.3 11.4 0.3 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2834) Polysacc_synt_C PF14667.6 KXH25515.1 - 1.2 9.2 7.7 0.66 10.0 1.3 2.2 2 0 0 2 2 2 0 Polysaccharide biosynthesis C-terminal domain Hydrolase PF00702.26 KXH25516.1 - 4.5e-06 27.1 0.0 5.7e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KXH25516.1 - 0.00036 20.7 0.0 0.00047 20.3 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Zn_clus PF00172.18 KXH25517.1 - 3.3e-07 30.3 13.7 3.3e-07 30.3 13.7 1.5 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXH25518.1 - 3.1e-09 36.3 0.0 5.6e-09 35.4 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_3_C PF01915.22 KXH25519.1 - 8.1e-40 137.0 0.1 2.2e-39 135.5 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KXH25519.1 - 9.9e-36 123.7 0.0 1.7e-35 122.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KXH25519.1 - 3.3e-24 84.8 0.1 5.6e-24 84.0 0.1 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain AA_permease_2 PF13520.6 KXH25521.1 - 2.9e-84 283.4 21.2 3.3e-84 283.2 21.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXH25521.1 - 2.5e-11 42.9 19.3 3.3e-11 42.4 19.3 1.1 1 0 0 1 1 1 1 Amino acid permease Aa_trans PF01490.18 KXH25521.1 - 0.053 12.2 11.7 0.15 10.7 11.7 2.0 1 1 0 1 1 1 0 Transmembrane amino acid transporter protein SPW PF03779.14 KXH25521.1 - 1.4 8.5 5.8 0.68 9.6 0.4 3.1 3 0 0 3 3 3 0 SPW repeat MS_channel PF00924.18 KXH25522.1 - 1.2e-16 60.9 0.2 1.2e-16 60.9 0.2 1.6 2 0 0 2 2 2 1 Mechanosensitive ion channel EF-hand_7 PF13499.6 KXH25522.1 - 0.049 14.1 0.2 3.4 8.2 0.0 3.2 2 1 0 2 2 2 0 EF-hand domain pair Fasciclin PF02469.22 KXH25523.1 - 5.5e-43 146.2 2.9 1.1e-22 80.6 0.6 2.2 2 0 0 2 2 2 2 Fasciclin domain Cyclin_C_2 PF16899.5 KXH25524.1 - 2e-36 124.5 0.0 9.7e-34 115.9 0.0 2.5 2 0 0 2 2 2 2 Cyclin C-terminal domain Cyclin_N PF00134.23 KXH25524.1 - 0.00072 19.3 0.1 0.0016 18.2 0.0 1.6 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KXH25524.1 - 0.05 13.7 0.1 2.6 8.2 0.0 2.6 3 0 0 3 3 3 0 Cyclin, C-terminal domain BAR PF03114.18 KXH25525.1 - 3.3e-49 167.7 3.7 4e-49 167.4 3.7 1.1 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.9 KXH25525.1 - 1.3e-07 31.1 0.8 1.6e-07 30.7 0.8 1.1 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking Ebp2 PF05890.12 KXH25525.1 - 0.00064 19.4 0.4 0.0012 18.4 0.4 1.4 1 0 0 1 1 1 1 Eukaryotic rRNA processing protein EBP2 OmpH PF03938.14 KXH25525.1 - 0.025 14.9 2.7 0.025 14.9 2.7 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) PMEI PF04043.15 KXH25525.1 - 0.063 13.6 0.2 0.11 12.8 0.2 1.4 1 0 0 1 1 1 0 Plant invertase/pectin methylesterase inhibitor TSNAXIP1_N PF15739.5 KXH25525.1 - 1.2 9.5 5.4 0.33 11.4 2.2 1.7 2 0 0 2 2 2 0 Translin-associated factor X-interacting N-terminus DUF883 PF05957.13 KXH25525.1 - 7.1 7.3 7.4 34 5.1 7.2 2.2 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) PLDc_2 PF13091.6 KXH25526.1 - 1.5e-17 63.7 0.0 6.7e-13 48.7 0.0 2.7 2 1 0 2 2 2 2 PLD-like domain PLDc PF00614.22 KXH25526.1 - 0.015 15.5 0.1 1 9.7 0.0 2.4 2 0 0 2 2 2 0 Phospholipase D Active site motif Regulator_TrmB PF11495.8 KXH25526.1 - 0.05 12.8 0.1 6.7 5.8 0.0 2.4 2 0 0 2 2 2 0 Archaeal transcriptional regulator TrmB ThuA PF06283.11 KXH25527.1 - 1.8e-59 201.4 0.2 7e-59 199.6 0.2 1.7 1 1 0 1 1 1 1 Trehalose utilisation Peptidase_M14 PF00246.24 KXH25528.1 - 1.4e-37 130.1 0.5 1.9e-37 129.7 0.5 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase MFS_1 PF07690.16 KXH25531.1 - 4.5e-25 88.3 44.0 4.9e-25 88.2 38.1 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 KXH25531.1 - 0.0012 18.2 12.5 0.0012 18.2 12.5 2.8 1 1 1 3 3 3 1 Uncharacterised MFS-type transporter YbfB TMEM132D_C PF15706.5 KXH25531.1 - 0.15 11.8 0.4 0.34 10.7 0.1 1.7 2 0 0 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term DUF1230 PF06799.11 KXH25531.1 - 0.19 11.9 0.2 0.19 11.9 0.2 2.3 2 1 0 2 2 2 0 Conserved in the green lineage and diatoms 27 DUF3624 PF12292.8 KXH25531.1 - 0.19 12.2 0.2 0.19 12.2 0.2 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF3624) Saf_2TM PF18303.1 KXH25531.1 - 0.67 9.5 5.9 7.5 6.1 0.5 2.9 3 0 0 3 3 3 0 SAVED-fused 2TM effector domain Peptidase_M20 PF01546.28 KXH25532.1 - 9.7e-30 103.8 0.0 1.5e-29 103.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KXH25532.1 - 1.7e-06 27.9 0.0 4e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KXH25532.1 - 0.064 12.9 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M28 TFR_dimer PF04253.15 KXH25533.1 - 2.1e-25 89.1 0.0 3.5e-25 88.5 0.0 1.3 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 KXH25533.1 - 5.6e-19 68.6 0.0 1.1e-18 67.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KXH25533.1 - 8.4e-13 48.2 0.0 2e-12 46.9 0.0 1.6 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 KXH25533.1 - 0.032 13.9 0.0 0.09 12.5 0.0 1.7 1 1 0 1 1 1 0 Peptidase family M20/M25/M40 Methyltransf_24 PF13578.6 KXH25534.1 - 8.1e-10 39.7 0.0 1.4e-09 38.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.17 KXH25534.1 - 3.6e-06 26.3 0.0 4.6e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Ammonium_transp PF00909.21 KXH25535.1 - 8.6e-119 396.8 31.8 9.8e-119 396.6 31.8 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family adh_short_C2 PF13561.6 KXH25536.1 - 2.8e-63 213.6 2.8 3.4e-63 213.3 2.8 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXH25536.1 - 7.2e-49 165.9 1.2 8.6e-49 165.7 1.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXH25536.1 - 6.7e-12 45.7 1.1 1e-11 45.1 1.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXH25536.1 - 0.097 12.1 0.3 1.9 7.9 0.1 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Peptidase_M28 PF04389.17 KXH25537.1 - 1.2e-35 123.1 0.0 1.5e-35 122.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KXH25537.1 - 3e-05 23.8 0.0 0.00017 21.4 0.0 2.1 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 KXH25537.1 - 0.00011 21.3 0.0 0.00022 20.3 0.0 1.5 1 1 0 1 1 1 1 M42 glutamyl aminopeptidase Nicastrin PF05450.15 KXH25537.1 - 0.017 14.6 0.0 0.03 13.8 0.0 1.4 1 0 0 1 1 1 0 Nicastrin DUF4910 PF16254.5 KXH25537.1 - 0.018 13.9 0.0 0.25 10.2 0.0 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4910) p450 PF00067.22 KXH25538.1 - 7.9e-52 176.5 0.0 1.1e-51 176.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KXH25539.1 - 2.7e-40 138.5 0.0 3.3e-40 138.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF4267 PF14087.6 KXH25540.1 - 4.5e-14 52.5 0.4 5.6e-14 52.2 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) Methyltransf_23 PF13489.6 KXH25541.1 - 2.1e-11 43.9 0.0 2.7e-11 43.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH25541.1 - 4.8e-09 36.8 0.0 1.4e-08 35.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH25541.1 - 1.2e-08 35.6 0.0 2.5e-08 34.6 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH25541.1 - 2.4e-08 34.6 0.0 4.3e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH25541.1 - 2.8e-07 30.4 0.0 3.4e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Pox_MCEL PF03291.16 KXH25541.1 - 0.0003 20.0 0.0 0.00039 19.6 0.0 1.1 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_18 PF12847.7 KXH25541.1 - 0.0004 20.3 0.0 0.00063 19.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXH25541.1 - 0.055 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain CMAS PF02353.20 KXH25541.1 - 0.18 11.1 0.0 0.29 10.4 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase ketoacyl-synt PF00109.26 KXH25542.1 - 2.1e-66 224.1 0.0 5.3e-66 222.8 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KXH25542.1 - 2.3e-60 203.6 0.6 4.5e-59 199.4 0.0 2.9 3 0 0 3 3 3 1 KR domain Acyl_transf_1 PF00698.21 KXH25542.1 - 1.9e-40 139.3 0.0 3.1e-40 138.6 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 KXH25542.1 - 1.1e-38 133.2 0.1 1.7e-38 132.6 0.1 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 KXH25542.1 - 1.6e-36 124.9 0.0 3.8e-36 123.7 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.26 KXH25542.1 - 5.1e-18 65.3 0.1 1.2e-17 64.1 0.1 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.12 KXH25542.1 - 1.8e-17 63.9 0.0 5.5e-17 62.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.6 KXH25542.1 - 5.7e-15 56.5 0.0 2.6e-14 54.4 0.0 2.3 2 0 0 2 2 1 1 Zinc-binding dehydrogenase KAsynt_C_assoc PF16197.5 KXH25542.1 - 2.5e-10 40.8 3.8 3.4e-09 37.2 0.2 3.1 2 1 0 2 2 1 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 KXH25542.1 - 3.3e-10 39.7 0.1 1.9e-07 30.7 0.0 2.6 2 0 0 2 2 2 2 short chain dehydrogenase Methyltransf_23 PF13489.6 KXH25542.1 - 7.6e-10 38.9 0.0 1.8e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH25542.1 - 1e-09 39.0 0.0 5.1e-09 36.7 0.0 2.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH25542.1 - 1e-09 38.9 0.0 3.9e-09 37.0 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH25542.1 - 3.2e-08 33.5 0.0 9.5e-08 32.0 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Thiolase_N PF00108.23 KXH25542.1 - 7.2e-06 25.6 0.0 1.5e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain PP-binding PF00550.25 KXH25542.1 - 0.00034 20.9 0.0 0.00099 19.4 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Ubie_methyltran PF01209.18 KXH25542.1 - 0.0012 18.2 0.0 0.0098 15.2 0.0 2.1 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family ACP_syn_III PF08545.10 KXH25542.1 - 0.0021 17.9 0.1 0.0068 16.2 0.1 1.9 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III adh_short_C2 PF13561.6 KXH25542.1 - 0.0025 17.4 0.2 0.033 13.8 0.0 2.4 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase M-inducer_phosp PF06617.13 KXH25542.1 - 0.17 11.2 0.0 0.31 10.3 0.0 1.3 1 0 0 1 1 1 0 M-phase inducer phosphatase Amidohydro_1 PF01979.20 KXH25543.1 - 3.9e-31 108.6 0.0 4.8e-31 108.3 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KXH25543.1 - 1e-07 31.8 0.5 5.5e-06 26.1 0.1 2.2 2 0 0 2 2 2 2 Amidohydrolase family Ytp1 PF10355.9 KXH25546.1 - 1e-67 228.3 18.8 1e-67 228.3 18.8 2.2 2 1 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 KXH25546.1 - 5.9e-32 109.6 4.6 5.9e-32 109.6 4.6 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) MFS_1 PF07690.16 KXH25547.1 - 3.7e-36 124.8 33.8 7.8e-36 123.7 33.4 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_72 PF03198.14 KXH25548.1 - 8.3e-119 396.5 6.3 1.1e-118 396.1 6.3 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 KXH25548.1 - 2.3e-22 79.4 4.1 6.7e-22 78.0 4.1 1.9 1 0 0 1 1 1 1 X8 domain BIR PF00653.21 KXH25550.1 - 5.3e-09 36.6 0.1 7.9e-09 36.1 0.1 1.3 1 0 0 1 1 1 1 Inhibitor of Apoptosis domain Mac PF12464.8 KXH25552.1 - 2.9e-14 53.0 0.0 4.5e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep PF00132.24 KXH25552.1 - 3.4e-12 45.6 12.0 6.4e-10 38.4 3.6 3.6 2 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KXH25552.1 - 1.2e-09 37.8 4.3 1.2e-09 37.8 4.3 3.2 3 1 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase DUF2306 PF10067.9 KXH25553.1 - 1.9e-31 109.2 7.2 2.8e-31 108.7 7.2 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2306) CitMHS PF03600.16 KXH25553.1 - 0.74 9.0 7.0 1.1 8.4 7.0 1.3 1 1 0 1 1 1 0 Citrate transporter Cerato-platanin PF07249.12 KXH25554.1 - 0.00015 21.9 0.3 0.00042 20.4 0.0 1.9 2 0 0 2 2 2 1 Cerato-platanin Amidase PF01425.21 KXH25555.1 - 3.1e-57 194.5 0.0 8.3e-49 166.8 0.0 2.1 2 0 0 2 2 2 2 Amidase Ish1 PF10281.9 KXH25555.1 - 0.16 12.3 0.6 20 5.6 0.0 2.7 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein Pyr_redox_3 PF13738.6 KXH25556.1 - 2.3e-25 89.5 0.0 6.9e-23 81.4 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXH25556.1 - 5.9e-19 68.4 0.0 1.6e-14 53.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KXH25556.1 - 2.8e-17 62.3 0.0 5.9e-16 58.0 0.0 2.1 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KXH25556.1 - 4.1e-16 59.1 0.1 4.4e-14 52.4 0.0 2.4 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 KXH25556.1 - 1.9e-10 40.5 0.7 1.2e-05 24.8 0.0 2.6 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.24 KXH25556.1 - 2e-06 27.6 0.5 3.1e-05 23.7 0.1 2.6 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KXH25556.1 - 3.2e-06 27.6 0.1 0.56 10.8 0.0 3.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KXH25556.1 - 3e-05 23.5 0.2 0.022 14.1 0.0 3.1 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 KXH25556.1 - 3.9e-05 23.7 1.1 0.3 11.1 0.1 3.0 2 1 1 3 3 3 2 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 KXH25556.1 - 0.00032 19.9 0.4 0.14 11.2 0.0 2.5 2 0 0 2 2 2 2 FAD binding domain HI0933_like PF03486.14 KXH25556.1 - 0.0016 17.2 0.6 0.99 8.0 0.1 2.8 3 0 0 3 3 3 2 HI0933-like protein Lycopene_cycl PF05834.12 KXH25556.1 - 0.0058 15.7 0.5 0.067 12.2 0.1 2.8 2 1 1 3 3 3 1 Lycopene cyclase protein Shikimate_DH PF01488.20 KXH25556.1 - 0.0063 16.6 0.0 1.3 9.1 0.0 3.1 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase GIDA PF01134.22 KXH25556.1 - 0.02 14.0 0.7 7.7 5.5 0.0 3.0 3 0 0 3 3 3 0 Glucose inhibited division protein A ApbA PF02558.16 KXH25556.1 - 0.12 12.0 0.0 0.48 10.1 0.0 2.0 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA TPR_2 PF07719.17 KXH25557.1 - 1.5e-10 40.4 6.5 2.9e-06 27.0 0.3 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 KXH25557.1 - 4.7e-08 32.5 3.4 0.0028 17.4 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KXH25557.1 - 1.1e-06 28.4 0.9 0.00031 20.7 0.1 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 KXH25557.1 - 9.6e-05 23.0 2.9 0.0059 17.2 1.6 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 KXH25557.1 - 0.00013 22.2 4.2 0.018 15.3 0.0 3.4 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 KXH25557.1 - 0.00038 20.9 0.4 0.005 17.3 0.1 2.7 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 KXH25557.1 - 0.07 14.0 4.7 0.55 11.2 0.4 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 KXH25557.1 - 0.082 12.6 1.8 6.8 6.5 0.0 3.2 3 1 0 3 3 3 0 TPR repeat TPR_10 PF13374.6 KXH25557.1 - 0.34 10.8 2.8 5.8 6.9 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 KXH25557.1 - 0.64 10.8 5.7 4.5 8.2 0.4 3.2 2 1 0 2 2 2 0 Tetratricopeptide repeat CAML PF14963.6 KXH25558.1 - 0.03 14.4 0.4 0.033 14.3 0.4 1.0 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand UQ_con PF00179.26 KXH25559.1 - 4.5e-25 87.9 0.0 1.5e-24 86.3 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme Glyco_hydro_6 PF01341.17 KXH25560.1 - 3.6e-108 361.9 0.8 4.9e-108 361.5 0.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 CBM_1 PF00734.18 KXH25560.1 - 3.9e-12 45.9 11.2 3.9e-12 45.9 11.2 2.5 2 0 0 2 2 2 1 Fungal cellulose binding domain MGC-24 PF05283.11 KXH25560.1 - 0.99 9.9 10.9 2.7 8.4 10.9 1.7 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Yeast-kill-tox PF09207.11 KXH25560.1 - 1.9 9.2 10.8 0.34 11.6 4.1 2.9 3 0 0 3 3 3 0 Yeast killer toxin E_Pc_C PF06752.12 KXH25560.1 - 4.1 7.5 11.5 7.5 6.6 11.5 1.4 1 0 0 1 1 1 0 Enhancer of Polycomb C-terminus Adap_comp_sub PF00928.21 KXH25561.1 - 4.6e-83 278.6 0.0 5.7e-83 278.3 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KXH25561.1 - 0.00011 22.2 0.2 0.00019 21.4 0.2 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain RIBIOP_C PF04950.12 KXH25561.1 - 0.068 12.6 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal muHD PF10291.9 KXH25561.1 - 0.069 12.6 0.1 0.14 11.5 0.1 1.5 1 0 0 1 1 1 0 Muniscin C-terminal mu homology domain Cu-oxidase_3 PF07732.15 KXH25563.1 - 1e-38 132.0 3.9 2.1e-38 131.0 3.9 1.6 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KXH25563.1 - 4.5e-35 120.4 10.4 1.2e-34 119.0 0.8 3.2 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.22 KXH25563.1 - 6.7e-22 78.3 1.9 2e-21 76.7 0.1 2.7 3 1 0 3 3 3 1 Multicopper oxidase DUF5488 PF17590.2 KXH25564.1 - 0.069 12.9 0.2 0.12 12.1 0.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5488) E1-E2_ATPase PF00122.20 KXH25565.1 - 8.3e-46 155.8 4.6 8.3e-46 155.8 4.6 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 KXH25565.1 - 2.9e-19 70.2 0.1 6e-19 69.2 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 KXH25565.1 - 8.3e-06 26.2 0.1 8.3e-06 26.2 0.1 2.4 3 0 0 3 3 3 1 Heavy-metal-associated domain Hydrolase_3 PF08282.12 KXH25565.1 - 3.3e-05 23.8 0.3 0.0003 20.6 0.2 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Peptidase_S10 PF00450.22 KXH25565.1 - 0.25 10.7 0.0 0.41 10.0 0.0 1.2 1 0 0 1 1 1 0 Serine carboxypeptidase Zn_clus PF00172.18 KXH25567.1 - 0.0024 18.0 3.6 0.0055 16.8 3.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AA_permease PF00324.21 KXH25568.1 - 3.1e-129 431.7 33.9 3.7e-129 431.4 33.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KXH25568.1 - 1.1e-41 143.1 38.1 1.4e-41 142.7 38.1 1.1 1 0 0 1 1 1 1 Amino acid permease Nucleos_tra2_C PF07662.13 KXH25569.1 - 6.4e-73 245.0 1.8 6.4e-73 245.0 1.8 2.8 3 1 0 3 3 3 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 KXH25569.1 - 9.6e-22 77.4 2.4 9.6e-22 77.4 2.4 3.3 4 1 1 5 5 5 1 Na+ dependent nucleoside transporter N-terminus ATP1G1_PLM_MAT8 PF02038.16 KXH25569.1 - 0.093 12.2 5.4 0.47 9.9 2.1 2.8 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family Gate PF07670.14 KXH25569.1 - 2.3 8.5 20.5 0.63 10.3 7.6 3.7 3 0 0 3 3 3 0 Nucleoside recognition Amidase PF01425.21 KXH25570.1 - 1.2e-73 248.7 0.0 7.6e-73 246.0 0.0 1.9 1 1 0 1 1 1 1 Amidase DUF3381 PF11861.8 KXH25571.1 - 0.017 14.9 7.0 0.022 14.6 7.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) Pox_H7 PF04787.12 KXH25571.1 - 0.54 10.8 2.7 0.78 10.3 2.7 1.1 1 0 0 1 1 1 0 Late protein H7 DUF4366 PF14283.6 KXH25571.1 - 2 8.4 7.9 0.14 12.2 1.8 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4366) Polyketide_cyc2 PF10604.9 KXH25573.1 - 1.3e-06 28.7 0.1 1.4e-06 28.6 0.1 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 KXH25573.1 - 0.0041 17.3 0.0 0.0059 16.8 0.0 1.4 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport MFS_1 PF07690.16 KXH25575.1 - 4.4e-40 137.7 34.1 2.8e-19 69.3 7.6 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH25575.1 - 9e-06 24.8 24.3 1.1e-05 24.5 8.4 4.0 3 1 0 3 3 3 2 Sugar (and other) transporter DUF2474 PF10617.9 KXH25575.1 - 0.11 12.3 1.7 6.9 6.6 0.1 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2474) OATP PF03137.20 KXH25575.1 - 4 5.6 8.3 13 3.9 4.2 3.1 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Cas_Csa5 PF09702.10 KXH25576.1 - 0.063 13.5 0.2 0.59 10.4 0.0 2.0 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Csa5) LIDHydrolase PF10230.9 KXH25577.1 - 2.4e-57 194.5 0.0 2.8e-57 194.3 0.0 1.0 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase MFS_1 PF07690.16 KXH25578.1 - 1.7e-25 89.7 36.7 2.1e-25 89.4 36.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Trp_oprn_chp PF09534.10 KXH25578.1 - 0.018 14.9 0.0 0.05 13.4 0.0 1.7 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) MFS_1 PF07690.16 KXH25579.1 - 7.2e-26 90.9 49.3 1e-15 57.6 21.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Syndecan PF01034.20 KXH25579.1 - 0.019 14.9 0.1 0.074 13.0 0.1 2.0 1 0 0 1 1 1 0 Syndecan domain Pec_lyase_C PF00544.19 KXH25580.1 - 5.2e-46 156.9 4.6 7.9e-46 156.3 4.6 1.2 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 KXH25580.1 - 0.00014 21.8 7.2 0.011 15.6 7.2 2.4 1 1 0 1 1 1 1 Right handed beta helix region Abhydrolase_1 PF00561.20 KXH25581.1 - 2e-09 37.5 0.1 5.8e-09 36.0 0.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXH25581.1 - 2.7e-05 23.6 0.0 0.0006 19.1 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KXH25581.1 - 0.045 14.3 0.0 0.066 13.8 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family RPE65 PF03055.15 KXH25582.1 - 7.9e-97 325.3 0.1 9e-97 325.2 0.1 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Abhydrolase_3 PF07859.13 KXH25583.1 - 2e-20 73.6 0.0 2.3e-19 70.1 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KXH25583.1 - 1.9e-07 30.8 0.0 0.0022 17.5 0.0 2.9 3 0 0 3 3 3 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 KXH25583.1 - 3.8e-06 27.7 1.3 5.1e-06 27.2 1.3 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.28 KXH25583.1 - 0.00013 21.0 0.1 0.0034 16.3 0.0 2.1 2 0 0 2 2 2 1 Carboxylesterase family Hydrolase_4 PF12146.8 KXH25583.1 - 0.00018 20.9 0.0 0.00065 19.0 0.0 1.9 2 1 0 2 2 2 1 Serine aminopeptidase, S33 DLH PF01738.18 KXH25583.1 - 0.0036 16.9 0.0 0.25 10.9 0.0 2.2 2 0 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 KXH25583.1 - 0.022 14.4 0.0 1.1 8.9 0.0 2.1 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 KXH25583.1 - 0.036 13.9 0.0 7.6 6.3 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Esterase PF00756.20 KXH25583.1 - 0.15 11.7 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 Putative esterase Fungal_trans PF04082.18 KXH25584.1 - 3.5e-08 32.8 0.3 8.2e-08 31.6 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain p450 PF00067.22 KXH25585.1 - 1e-58 199.2 0.0 1.3e-57 195.7 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 DUF1993 PF09351.10 KXH25587.1 - 7.1e-55 185.5 0.1 7.9e-55 185.4 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) LpxI_C PF06230.11 KXH25587.1 - 0.092 12.6 0.1 0.14 12.0 0.1 1.3 1 0 0 1 1 1 0 LpxI C-terminal domain Pyr_redox_2 PF07992.14 KXH25588.1 - 2.9e-09 36.6 0.0 1.3e-05 24.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXH25588.1 - 2e-07 31.1 0.1 6.3e-07 29.5 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.19 KXH25588.1 - 3.7e-06 25.7 0.2 3.2e-05 22.6 0.1 2.3 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KXH25588.1 - 5.5e-05 22.5 1.3 0.002 17.3 0.4 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KXH25588.1 - 0.00042 19.7 0.0 0.004 16.5 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXH25588.1 - 0.0016 18.5 0.0 0.29 11.1 0.0 2.6 2 0 0 2 2 2 1 FAD-NAD(P)-binding Amino_oxidase PF01593.24 KXH25588.1 - 0.012 14.9 0.1 3.1 7.0 0.0 2.8 3 1 0 4 4 4 0 Flavin containing amine oxidoreductase MetW PF07021.12 KXH25588.1 - 0.094 12.3 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Sas6_CC PF18594.1 KXH25588.1 - 0.12 12.2 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 Sas6/XLF/XRCC4 coiled-coil domain Methyltransf_2 PF00891.18 KXH25589.1 - 1.7e-19 70.0 0.0 3e-19 69.2 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain Phage_fiber_2 PF03406.13 KXH25589.1 - 4.5 6.9 6.6 6.1 6.5 0.2 2.3 2 0 0 2 2 2 0 Phage tail fibre repeat HsbA PF12296.8 KXH25590.1 - 1.5e-30 106.1 16.7 1.5e-30 106.1 16.7 2.1 2 0 0 2 2 2 1 Hydrophobic surface binding protein A AAA_12 PF13087.6 KXH25591.1 - 7.5e-40 136.7 0.0 1.6e-39 135.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KXH25591.1 - 4.3e-38 130.7 0.0 5.5e-13 49.5 0.0 4.7 4 0 0 4 4 4 3 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 KXH25591.1 - 5.3e-30 105.1 25.8 4.6e-26 92.2 0.0 6.4 6 0 0 6 6 6 2 AAA domain AAA_lid_6 PF17866.1 KXH25591.1 - 8.1e-20 70.8 5.8 5.8e-12 45.6 1.5 3.4 2 0 0 2 2 2 2 AAA lid domain AAA_30 PF13604.6 KXH25591.1 - 2.5e-18 66.5 0.7 0.015 15.1 0.0 5.6 5 0 0 5 5 5 5 AAA domain AAA_19 PF13245.6 KXH25591.1 - 3.1e-13 50.3 2.0 0.0036 17.7 0.0 6.0 4 2 0 4 4 4 3 AAA domain AAA_5 PF07728.14 KXH25591.1 - 1.1e-09 38.4 0.6 0.095 12.7 0.0 4.5 3 0 0 3 3 3 3 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KXH25591.1 - 3.8e-08 33.9 3.8 0.33 11.3 0.1 5.8 4 1 1 5 5 5 2 AAA ATPase domain RuvB_N PF05496.12 KXH25591.1 - 1e-07 31.9 0.0 0.24 11.2 0.0 3.8 3 1 0 3 3 3 3 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 KXH25591.1 - 4.3e-07 29.5 0.1 0.21 11.0 0.0 3.9 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 KXH25591.1 - 1.4e-06 28.2 1.5 0.98 9.1 0.0 4.0 3 0 0 3 3 3 3 AAA domain Torsin PF06309.11 KXH25591.1 - 1.2e-05 25.4 0.1 3.3 7.8 0.0 4.1 4 0 0 4 4 4 1 Torsin AAA_33 PF13671.6 KXH25591.1 - 3e-05 24.2 1.5 1.8 8.7 0.0 4.4 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 KXH25591.1 - 3.5e-05 24.2 0.1 2.5 8.5 0.0 3.8 3 0 0 3 3 3 1 RNA helicase IstB_IS21 PF01695.17 KXH25591.1 - 3.8e-05 23.5 0.0 1.7 8.4 0.0 3.6 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_22 PF13401.6 KXH25591.1 - 0.00016 22.0 18.8 0.48 10.7 0.1 7.8 6 3 0 6 6 4 2 AAA domain AAA_7 PF12775.7 KXH25591.1 - 0.0021 17.6 0.6 3.6 7.1 0.0 3.4 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_18 PF13238.6 KXH25591.1 - 0.0039 17.7 12.5 2.5 8.7 0.1 5.4 5 0 0 5 5 4 1 AAA domain NTPase_1 PF03266.15 KXH25591.1 - 0.062 13.2 3.1 24 4.8 0.1 4.1 4 0 0 4 4 4 0 NTPase Acyl-CoA_dh_1 PF00441.24 KXH25591.1 - 0.074 13.3 0.2 0.22 11.8 0.2 1.7 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain AAA_6 PF12774.7 KXH25591.1 - 0.1 11.6 0.1 3.8 6.4 0.0 2.8 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region Helicase_RecD PF05127.14 KXH25591.1 - 0.13 12.1 2.1 8.4 6.2 0.0 3.7 4 0 0 4 4 4 0 Helicase SRP54 PF00448.22 KXH25591.1 - 0.24 11.0 6.1 9 5.9 0.0 4.2 4 0 0 4 4 4 0 SRP54-type protein, GTPase domain HDV_ag PF01517.18 KXH25591.1 - 0.38 10.5 15.5 0.052 13.3 2.2 2.8 2 0 0 2 2 2 0 Hepatitis delta virus delta antigen ABC_tran PF00005.27 KXH25591.1 - 0.49 10.9 6.2 17 5.9 0.1 4.3 3 1 1 4 4 4 0 ABC transporter AAA_17 PF13207.6 KXH25591.1 - 2.9 8.3 18.3 3.2 8.2 0.1 5.3 5 0 0 5 5 4 0 AAA domain DUF3684 PF12449.8 KXH25592.1 - 0.15 9.8 0.1 0.19 9.4 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3684) RNase_T PF00929.24 KXH25593.1 - 5.2e-05 23.8 0.1 0.0018 18.9 0.0 2.2 2 0 0 2 2 2 2 Exonuclease LRR_6 PF13516.6 KXH25594.1 - 7.5e-15 53.7 21.3 0.63 10.2 0.0 11.8 12 0 0 12 12 12 5 Leucine Rich repeat F-box-like PF12937.7 KXH25594.1 - 3.5e-12 46.0 0.4 8.3e-12 44.8 0.4 1.7 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KXH25594.1 - 3.7e-09 36.7 14.2 0.43 11.1 0.1 7.3 3 2 3 8 8 8 5 Leucine Rich repeats (2 copies) F-box PF00646.33 KXH25594.1 - 2.6e-05 23.9 0.1 0.0001 22.1 0.1 2.0 1 0 0 1 1 1 1 F-box domain LRR_1 PF00560.33 KXH25594.1 - 1.7 9.5 20.0 1.4e+02 3.6 0.0 8.4 8 2 0 8 8 8 0 Leucine Rich Repeat KAR9 PF08580.10 KXH25595.1 - 1.7 7.1 9.6 2.2 6.7 9.6 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Chalcone_2 PF16035.5 KXH25596.1 - 5.2e-81 271.3 0.0 7.2e-81 270.8 0.0 1.2 1 0 0 1 1 1 1 Chalcone isomerase like Chalcone_3 PF16036.5 KXH25596.1 - 0.0019 18.4 0.2 0.062 13.4 0.1 2.3 1 1 1 2 2 2 1 Chalcone isomerase-like Glutaredoxin PF00462.24 KXH25597.1 - 2.5e-18 66.1 0.0 3.6e-18 65.5 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_2 PF13098.6 KXH25597.1 - 0.0006 20.2 0.1 0.00084 19.8 0.1 1.5 1 1 0 1 1 1 1 Thioredoxin-like domain DUF836 PF05768.14 KXH25597.1 - 0.0015 18.9 0.0 0.0018 18.6 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) DSBA PF01323.20 KXH25597.1 - 0.0029 17.4 0.2 0.0068 16.2 0.1 1.5 1 1 0 2 2 2 1 DSBA-like thioredoxin domain Thioredoxin PF00085.20 KXH25597.1 - 0.0035 17.3 0.0 0.0037 17.2 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_9 PF14595.6 KXH25597.1 - 0.019 14.7 0.0 0.023 14.5 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin GST_N_3 PF13417.6 KXH25597.1 - 0.04 14.3 0.0 0.06 13.8 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain TraF PF13728.6 KXH25597.1 - 0.058 13.2 0.0 0.058 13.2 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein Thioredoxin_3 PF13192.6 KXH25597.1 - 0.1 12.7 0.0 0.14 12.2 0.0 1.4 1 1 0 1 1 1 0 Thioredoxin domain BAG PF02179.16 KXH25598.1 - 4.6e-21 75.0 2.2 7.7e-21 74.3 2.2 1.4 1 0 0 1 1 1 1 BAG domain ubiquitin PF00240.23 KXH25598.1 - 6.4e-05 22.6 0.0 0.00028 20.6 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin family Ubiquitin_5 PF18037.1 KXH25598.1 - 0.006 16.9 0.0 0.028 14.8 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin-like domain Ribosomal_L13 PF00572.18 KXH25599.1 - 4.5e-11 43.1 0.0 4e-09 36.8 0.0 2.3 1 1 0 1 1 1 1 Ribosomal protein L13 DSBA PF01323.20 KXH25599.1 - 0.035 13.9 0.1 0.046 13.5 0.1 1.4 1 0 0 1 1 1 0 DSBA-like thioredoxin domain Swi5 PF07061.11 KXH25600.1 - 6.4e-20 71.0 0.1 7.2e-20 70.9 0.1 1.1 1 0 0 1 1 1 1 Swi5 Latarcin PF10279.9 KXH25600.1 - 0.027 14.8 0.2 0.036 14.5 0.2 1.3 1 1 0 1 1 1 0 Latarcin precursor Ank_2 PF12796.7 KXH25601.1 - 2.3e-22 79.4 0.0 1.8e-08 34.8 0.0 6.8 5 2 2 7 7 7 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXH25601.1 - 2.4e-19 67.4 8.2 0.0019 18.6 0.1 9.3 10 0 0 10 10 10 5 Ankyrin repeat Ank_4 PF13637.6 KXH25601.1 - 9e-19 67.6 3.2 0.00023 21.7 0.0 6.9 5 1 2 7 7 7 5 Ankyrin repeats (many copies) Ank PF00023.30 KXH25601.1 - 1.6e-11 44.1 5.8 0.0077 16.6 0.2 6.5 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 KXH25601.1 - 4.6e-07 30.0 5.7 0.02 15.2 0.0 6.1 6 1 0 6 6 6 1 Ankyrin repeats (many copies) Clr5 PF14420.6 KXH25601.1 - 0.004 17.3 0.7 0.0086 16.3 0.7 1.5 1 0 0 1 1 1 1 Clr5 domain CIDR1_gamma PF18562.1 KXH25601.1 - 0.1 12.7 1.5 0.28 11.3 1.5 1.7 1 0 0 1 1 1 0 Cysteine-Rich Interdomain Region 1 gamma Abhydrolase_1 PF00561.20 KXH25602.1 - 3e-19 69.7 0.0 1.6e-18 67.3 0.0 2.0 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXH25602.1 - 2.6e-13 51.1 0.0 3.5e-13 50.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXH25602.1 - 1.3e-12 47.5 0.0 2.3e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 KXH25602.1 - 3.8e-05 22.5 0.0 6.4e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 Ndr family Peptidase_S9 PF00326.21 KXH25602.1 - 0.083 12.4 0.4 7.4 6.0 0.0 2.6 2 1 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_5 PF12695.7 KXH25602.1 - 0.092 12.5 0.0 0.24 11.2 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase family COesterase PF00135.28 KXH25604.1 - 2e-70 238.1 0.0 3.4e-70 237.4 0.0 1.2 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXH25604.1 - 0.00019 21.4 0.0 0.00046 20.1 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Epimerase PF01370.21 KXH25605.1 - 4.8e-18 65.5 0.0 7e-18 65.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXH25605.1 - 5.9e-12 45.2 0.0 9.9e-12 44.4 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KXH25605.1 - 6.1e-09 36.0 0.0 4.7e-08 33.1 0.0 2.0 2 0 0 2 2 2 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KXH25605.1 - 7.7e-09 35.4 0.0 3.6e-08 33.2 0.0 2.1 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KXH25605.1 - 3.2e-08 33.1 0.0 0.0026 17.0 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein KR PF08659.10 KXH25605.1 - 0.00014 21.9 0.0 0.00027 20.9 0.0 1.5 1 0 0 1 1 1 1 KR domain NmrA PF05368.13 KXH25605.1 - 0.00021 20.9 0.1 0.0045 16.6 0.1 2.5 2 1 0 2 2 2 1 NmrA-like family adh_short PF00106.25 KXH25605.1 - 0.00078 19.0 0.0 0.0031 17.0 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase Polysacc_synt_2 PF02719.15 KXH25605.1 - 0.00093 18.4 0.0 0.0016 17.6 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KXH25605.1 - 0.14 11.3 0.0 0.25 10.4 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain adh_short PF00106.25 KXH25606.1 - 3e-23 82.3 0.0 1.6e-22 80.0 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXH25606.1 - 2.5e-16 59.9 0.0 5.8e-16 58.7 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH25606.1 - 1.6e-06 28.2 0.1 3e-06 27.3 0.1 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXH25606.1 - 0.0026 17.2 0.0 0.0059 16.1 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.8 KXH25606.1 - 0.077 12.8 0.1 0.28 11.0 0.0 1.9 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Methyltransf_23 PF13489.6 KXH25607.1 - 3.5e-11 43.2 0.0 4.4e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH25607.1 - 5.8e-07 30.1 0.0 1.1e-06 29.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH25607.1 - 6e-07 30.0 0.0 1.2e-06 29.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH25607.1 - 1.2e-06 29.2 0.0 2e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH25607.1 - 3.7e-06 26.8 0.0 5e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXH25607.1 - 0.00032 20.1 0.0 0.00045 19.6 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_24 PF13578.6 KXH25607.1 - 0.011 16.8 0.0 0.017 16.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PRMT5 PF05185.16 KXH25607.1 - 0.074 12.9 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase CN_hydrolase PF00795.22 KXH25608.1 - 7.3e-43 146.8 0.0 8.7e-43 146.5 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase FAD_binding_4 PF01565.23 KXH25609.1 - 2.4e-16 59.7 0.0 4e-16 59.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Sugar_tr PF00083.24 KXH25611.1 - 9.5e-116 387.3 27.2 1.1e-115 387.1 27.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH25611.1 - 2.3e-23 82.7 30.3 8.6e-23 80.8 21.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily YjcB PF15940.5 KXH25611.1 - 2.1 8.6 7.6 0.19 11.9 1.0 2.6 2 1 1 3 3 3 0 Family of unknown function DUF1201 PF06716.11 KXH25611.1 - 5.7 7.0 10.2 0.43 10.6 3.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1201) Sulfatase PF00884.23 KXH25612.1 - 8e-62 209.4 0.1 1.1e-61 209.0 0.1 1.2 1 0 0 1 1 1 1 Sulfatase DUF4976 PF16347.5 KXH25612.1 - 1.9e-20 73.0 10.4 2.8e-20 72.5 6.9 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF4976) Phosphodiest PF01663.22 KXH25612.1 - 2.6e-10 40.4 2.5 1.1e-09 38.4 2.5 1.9 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 KXH25612.1 - 0.00032 19.5 0.0 0.0011 17.6 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF229) Zn_clus PF00172.18 KXH25613.1 - 5.9e-13 48.7 24.3 1.1e-06 28.6 11.6 2.6 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXH25613.1 - 2.2e-06 26.9 0.0 3.8e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_3 PF00933.21 KXH25615.1 - 4.9e-49 167.4 0.0 7.8e-49 166.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 KXH25615.1 - 5.3e-38 131.0 0.0 9.5e-38 130.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 KXH25615.1 - 2e-14 53.5 0.1 3.7e-14 52.6 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain MFS_1 PF07690.16 KXH25616.1 - 1.1e-46 159.4 47.1 3.1e-46 157.9 44.2 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH25616.1 - 8.1e-11 41.4 4.7 8.1e-11 41.4 4.7 3.0 2 1 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.13 KXH25616.1 - 5.2e-07 28.5 18.4 3.7e-06 25.7 18.5 2.2 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Fungal_trans PF04082.18 KXH25617.1 - 2.2e-11 43.3 0.0 3.2e-11 42.8 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH25617.1 - 2.1e-08 34.2 9.7 3.7e-08 33.3 9.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GMC_oxred_N PF00732.19 KXH25618.1 - 3.4e-65 220.3 0.0 4.7e-65 219.9 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXH25618.1 - 1.4e-31 110.0 0.0 2.4e-31 109.2 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KXH25618.1 - 0.00021 20.5 0.1 0.00035 19.7 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 KXH25618.1 - 0.018 14.1 1.4 3 6.8 0.8 2.2 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.17 KXH25618.1 - 0.02 14.2 0.8 0.044 13.0 0.2 1.9 2 0 0 2 2 2 0 Thi4 family Sugar_tr PF00083.24 KXH25619.1 - 5.3e-110 368.4 21.5 1.5e-109 366.9 21.5 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH25619.1 - 2.9e-22 79.1 52.1 1.2e-16 60.6 24.9 2.8 1 1 2 3 3 3 2 Major Facilitator Superfamily DUF910 PF06014.11 KXH25619.1 - 0.074 13.1 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF910) DUF89 PF01937.19 KXH25620.1 - 4.3e-136 453.5 0.1 4.9e-136 453.3 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 Lustrin_cystein PF14625.6 KXH25621.1 - 0.66 10.4 10.2 4.6 7.7 1.1 2.6 2 0 0 2 2 2 0 Lustrin, cysteine-rich repeated domain Stealth_CR4 PF17103.5 KXH25624.1 - 0.099 12.5 0.0 0.31 11.0 0.0 1.8 1 0 0 1 1 1 0 Stealth protein CR4, conserved region 4 DUF3435 PF11917.8 KXH25644.1 - 8e-112 374.2 0.1 1.7e-111 373.1 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3435) Phage_int_SAM_5 PF13102.6 KXH25644.1 - 0.036 14.4 0.1 0.19 12.1 0.0 2.2 2 0 0 2 2 2 0 Phage integrase SAM-like domain zf-C2H2 PF00096.26 KXH25644.1 - 6.9 7.3 12.6 3.4 8.3 3.2 2.9 2 0 0 2 2 2 0 Zinc finger, C2H2 type Ribosom_S30AE_C PF16321.5 KXH25648.1 - 1.1 9.1 2.7 83 3.0 0.3 3.6 4 0 0 4 4 4 0 Sigma 54 modulation/S30EA ribosomal protein C terminus Cyclin_N2 PF16500.5 KXH25648.1 - 3.5 8.4 8.2 10 6.9 0.4 3.5 3 1 1 4 4 4 0 N-terminal region of cyclin_N DUF647 PF04884.14 KXH25649.1 - 6.3e-93 310.8 3.3 1.2e-92 310.0 1.8 2.0 2 0 0 2 2 2 1 Vitamin B6 photo-protection and homoeostasis MDD_C PF18376.1 KXH25649.1 - 1.1e-62 211.1 0.0 1.8e-62 210.4 0.0 1.4 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 KXH25649.1 - 3.1e-08 33.7 0.7 3.1e-08 33.7 0.7 2.9 4 0 0 4 4 4 1 GHMP kinases N terminal domain S36_mt PF10937.8 KXH25650.1 - 6.5e-35 121.2 4.3 1.1e-31 110.8 2.1 2.2 1 1 1 2 2 2 2 Ribosomal protein S36, mitochondrial DUF4267 PF14087.6 KXH25651.1 - 1.8e-17 63.4 3.4 2e-17 63.2 3.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) Cyto_heme_lyase PF01265.17 KXH25652.1 - 2.6e-43 148.7 27.2 6.7e-42 144.1 17.0 3.7 1 1 1 2 2 2 2 Cytochrome c/c1 heme lyase TRI5 PF06330.11 KXH25653.1 - 7.6e-09 34.9 0.0 1e-08 34.5 0.0 1.1 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) MFS_1 PF07690.16 KXH25654.1 - 5.8e-44 150.5 62.2 2.8e-41 141.6 46.2 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF5345 PF17280.2 KXH25654.1 - 0.49 10.4 5.6 0.42 10.6 2.6 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5345) ABC2_membrane PF01061.24 KXH25655.1 - 3.6e-81 271.6 65.8 9.6e-42 142.8 18.8 3.8 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 KXH25655.1 - 1.7e-37 129.0 0.1 3.7e-17 63.1 0.0 2.8 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.12 KXH25655.1 - 6.2e-37 125.4 4.6 8.1e-30 102.6 0.2 3.1 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.6 KXH25655.1 - 2.2e-19 69.9 0.0 5.4e-19 68.6 0.0 1.7 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_25 PF13481.6 KXH25655.1 - 2.2e-07 30.6 0.2 6.2e-05 22.7 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 KXH25655.1 - 1.6e-06 28.6 0.3 0.00043 20.7 0.1 2.7 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 KXH25655.1 - 1.1e-05 25.3 0.1 0.0053 16.7 0.0 2.6 2 0 0 2 2 2 1 RsgA GTPase AAA_33 PF13671.6 KXH25655.1 - 2.7e-05 24.3 0.2 0.0018 18.5 0.1 2.7 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KXH25655.1 - 0.00068 20.2 0.0 0.011 16.3 0.0 2.6 3 0 0 3 3 2 1 AAA domain AAA_29 PF13555.6 KXH25655.1 - 0.0012 18.6 2.3 0.052 13.3 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.6 KXH25655.1 - 0.0052 17.1 0.8 2 8.7 0.1 2.9 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 KXH25655.1 - 0.0063 16.1 2.0 0.055 13.1 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 KXH25655.1 - 0.0077 16.0 0.2 0.97 9.1 0.1 2.4 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 KXH25655.1 - 0.013 15.0 0.0 3.7 6.9 0.0 3.2 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KXH25655.1 - 0.014 15.2 0.0 1.2 8.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 KXH25655.1 - 0.022 14.8 0.1 6.5 6.9 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase Ploopntkinase3 PF18751.1 KXH25655.1 - 0.1 12.5 0.3 1 9.2 0.0 2.3 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 dNK PF01712.19 KXH25655.1 - 0.14 12.0 0.0 2.5 7.9 0.0 2.2 2 0 0 2 2 2 0 Deoxynucleoside kinase NACHT PF05729.12 KXH25655.1 - 0.15 11.9 2.7 2.4 8.1 0.3 2.6 2 0 0 2 2 2 0 NACHT domain AAA_17 PF13207.6 KXH25655.1 - 0.16 12.4 0.9 1.9 8.9 0.0 2.7 3 0 0 3 3 2 0 AAA domain RNA_helicase PF00910.22 KXH25655.1 - 0.18 12.2 0.1 37 4.8 0.0 2.7 2 0 0 2 2 2 0 RNA helicase ADH_N PF08240.12 KXH25657.1 - 5.1e-07 29.5 0.0 5.3e-06 26.3 0.0 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain GMC_oxred_N PF00732.19 KXH25658.1 - 3.3e-64 217.1 0.1 4.3e-64 216.7 0.1 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXH25658.1 - 1.6e-28 100.1 0.0 3.3e-28 99.0 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KXH25658.1 - 3e-05 24.2 0.0 0.00062 19.9 0.1 2.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXH25658.1 - 0.00013 21.6 0.4 0.0025 17.4 0.0 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KXH25658.1 - 0.00016 20.9 0.2 0.00038 19.6 0.2 1.6 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 KXH25658.1 - 0.00033 20.0 0.1 0.00068 18.9 0.1 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 KXH25658.1 - 0.0041 16.3 0.8 0.021 13.9 0.5 2.0 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 KXH25658.1 - 0.011 14.5 0.2 0.1 11.2 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_3 PF13738.6 KXH25658.1 - 0.014 14.7 1.2 0.11 11.8 0.3 2.3 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXH25658.1 - 0.017 14.4 0.7 0.097 11.9 0.3 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXH25658.1 - 0.05 13.6 0.6 0.21 11.5 0.1 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding TrkA_N PF02254.18 KXH25658.1 - 0.13 12.5 0.1 0.56 10.5 0.1 2.1 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox PF00070.27 KXH25658.1 - 0.16 12.5 0.3 1.1 9.9 0.3 2.4 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase DUF1674 PF07896.12 KXH25659.1 - 0.021 15.3 0.2 0.037 14.5 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1674) DUF5336 PF17270.2 KXH25659.1 - 0.055 13.1 0.0 0.066 12.8 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5336) Pex14_N PF04695.13 KXH25660.1 - 0.025 15.2 2.5 0.04 14.6 2.5 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Alpha_GJ PF03229.13 KXH25660.1 - 0.62 10.6 11.0 1 9.9 11.0 1.3 1 0 0 1 1 1 0 Alphavirus glycoprotein J CLN3 PF02487.17 KXH25661.1 - 8.1e-165 548.7 7.5 9.3e-165 548.5 7.5 1.0 1 0 0 1 1 1 1 CLN3 protein MFS_1 PF07690.16 KXH25661.1 - 0.02 13.8 25.3 0.016 14.2 7.8 2.5 1 1 1 2 2 2 0 Major Facilitator Superfamily Acetyltransf_8 PF13523.6 KXH25662.1 - 1.2e-43 148.2 0.1 1.9e-43 147.6 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain MCU PF04678.13 KXH25663.1 - 8.2e-23 81.4 0.1 8.2e-23 81.4 0.1 2.2 3 0 0 3 3 3 1 Mitochondrial calcium uniporter p450 PF00067.22 KXH25664.1 - 1.7e-27 96.3 0.0 3.9e-26 91.8 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 Glyco_hydro_79C PF16862.5 KXH25665.1 - 4.6e-14 53.1 0.0 1.9e-13 51.2 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolase family 79 C-terminal beta domain Lipase_GDSL PF00657.22 KXH25667.1 - 0.11 12.5 0.3 0.16 12.0 0.3 1.5 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase GH131_N PF18271.1 KXH25668.1 - 3.3e-77 259.7 0.1 3.7e-77 259.5 0.1 1.0 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain Amino_oxidase PF01593.24 KXH25669.1 - 2e-57 195.5 0.0 2.4e-57 195.2 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KXH25669.1 - 1.1e-12 48.0 0.2 2.4e-12 46.9 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KXH25669.1 - 1.8e-06 27.6 0.1 2.8e-06 27.0 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KXH25669.1 - 4e-06 26.2 0.1 7.3e-06 25.3 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KXH25669.1 - 6.5e-06 25.6 0.0 1.2e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXH25669.1 - 8.4e-06 25.6 0.0 1.4e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KXH25669.1 - 1.5e-05 25.5 0.3 3.8e-05 24.2 0.2 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXH25669.1 - 4.3e-05 22.9 0.0 0.27 10.5 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXH25669.1 - 0.00014 21.2 0.0 0.00023 20.5 0.0 1.2 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 KXH25669.1 - 0.00017 20.4 0.2 0.00027 19.8 0.2 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.19 KXH25669.1 - 0.00032 20.1 0.1 0.00052 19.4 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 KXH25669.1 - 0.0027 16.9 0.2 0.0041 16.2 0.2 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 KXH25669.1 - 0.039 13.2 0.0 0.067 12.5 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Rtt106 PF08512.12 KXH25671.1 - 1.2e-29 102.6 0.0 2e-29 101.8 0.0 1.4 1 0 0 1 1 1 1 Histone chaperone Rttp106-like PH_18 PF18469.1 KXH25671.1 - 0.11 12.4 0.0 0.4 10.7 0.0 1.9 1 1 0 1 1 1 0 Pleckstrin homology domain Cwf_Cwc_15 PF04889.12 KXH25671.1 - 0.12 12.1 22.8 0.18 11.5 22.8 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Paf1 PF03985.13 KXH25671.1 - 4.9 6.0 12.4 6.3 5.7 12.4 1.1 1 0 0 1 1 1 0 Paf1 Vfa1 PF08432.10 KXH25672.1 - 1.2e-41 143.0 26.8 1.4e-41 142.8 26.8 1.0 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 SpoIIIAH PF12685.7 KXH25672.1 - 0.0021 17.9 14.0 0.0026 17.6 14.0 1.1 1 0 0 1 1 1 1 SpoIIIAH-like protein CDC45 PF02724.14 KXH25672.1 - 0.0068 14.8 15.1 0.007 14.7 15.1 1.0 1 0 0 1 1 1 1 CDC45-like protein RNA_pol_Rpc4 PF05132.14 KXH25672.1 - 0.025 15.0 13.1 0.036 14.5 13.1 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF913 PF06025.12 KXH25672.1 - 0.059 12.4 7.5 0.06 12.3 7.5 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) SprA-related PF12118.8 KXH25672.1 - 0.06 12.5 12.0 0.055 12.6 12.0 1.1 1 0 0 1 1 1 0 SprA-related family Afi1 PF07792.12 KXH25672.1 - 0.1 13.1 12.2 0.14 12.6 12.2 1.4 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking RR_TM4-6 PF06459.12 KXH25672.1 - 0.12 12.2 21.8 0.14 12.0 21.8 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SAPS PF04499.15 KXH25672.1 - 0.15 10.8 10.8 0.15 10.8 10.8 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DDHD PF02862.17 KXH25672.1 - 0.17 12.0 7.0 0.2 11.8 7.0 1.1 1 0 0 1 1 1 0 DDHD domain Zip PF02535.22 KXH25672.1 - 0.21 10.8 10.2 0.25 10.5 10.2 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter PPL5 PF18168.1 KXH25672.1 - 0.24 10.7 11.8 0.29 10.4 11.8 1.2 1 0 0 1 1 1 0 Prim-pol family 5 SLC12 PF03522.15 KXH25672.1 - 0.26 10.3 12.4 0.29 10.1 12.4 1.0 1 0 0 1 1 1 0 Solute carrier family 12 RPN2_C PF18004.1 KXH25672.1 - 0.29 11.0 27.7 0.52 10.2 27.7 1.4 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain DUF4746 PF15928.5 KXH25672.1 - 0.31 10.4 18.1 0.36 10.2 18.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF4820 PF16091.5 KXH25672.1 - 0.49 9.7 10.3 0.57 9.5 10.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) AAA_11 PF13086.6 KXH25672.1 - 0.56 9.9 12.9 0.65 9.7 12.9 1.1 1 0 0 1 1 1 0 AAA domain SID-1_RNA_chan PF13965.6 KXH25672.1 - 0.78 8.1 3.6 0.78 8.1 3.6 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Serinc PF03348.15 KXH25672.1 - 0.78 8.6 5.7 0.84 8.5 5.7 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) Connexin PF00029.19 KXH25672.1 - 1.3 8.8 17.0 0.97 9.1 14.4 1.9 2 0 0 2 2 2 0 Connexin Neur_chan_memb PF02932.16 KXH25672.1 - 1.3 9.1 5.9 1.4 8.9 5.9 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region EOS1 PF12326.8 KXH25672.1 - 1.3 8.9 3.2 1.6 8.7 3.2 1.3 1 0 0 1 1 1 0 N-glycosylation protein Membralin PF09746.9 KXH25672.1 - 1.8 7.5 7.2 2.2 7.2 7.2 1.1 1 0 0 1 1 1 0 Tumour-associated protein SpoIIP PF07454.11 KXH25672.1 - 1.8 7.9 19.9 2.3 7.6 19.9 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) PTPRCAP PF15713.5 KXH25672.1 - 1.9 8.8 19.8 2.7 8.3 19.8 1.2 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated DUF3807 PF12720.7 KXH25672.1 - 2.2 8.5 24.3 2.9 8.2 24.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) RNA_pol_3_Rpc31 PF11705.8 KXH25672.1 - 2.2 8.5 28.9 2.7 8.2 28.9 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 CLN3 PF02487.17 KXH25672.1 - 2.6 7.0 8.0 3 6.8 8.0 1.1 1 0 0 1 1 1 0 CLN3 protein GCD14 PF08704.10 KXH25672.1 - 2.6 7.6 6.7 2.8 7.6 6.7 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit VIR_N PF15912.5 KXH25672.1 - 2.7 7.5 14.9 3.1 7.3 14.9 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal GAGA_bind PF06217.12 KXH25672.1 - 3.6 7.8 14.8 3.7 7.8 14.8 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family CSG2 PF16965.5 KXH25672.1 - 3.9 6.3 6.8 4.7 6.0 6.8 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator MCM_bind PF09739.9 KXH25672.1 - 3.9 5.8 17.1 4.6 5.6 17.1 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor DUF2828 PF11443.8 KXH25672.1 - 4.5 5.2 16.9 5.3 5.0 16.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) CobT PF06213.12 KXH25672.1 - 4.9 6.5 22.8 6.7 6.0 22.8 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Astro_capsid_p PF12226.8 KXH25672.1 - 5.5 6.1 12.5 6.4 5.8 12.5 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein NPR3 PF03666.13 KXH25672.1 - 6 5.5 20.5 7.2 5.3 20.5 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 RPOL_N PF14700.6 KXH25672.1 - 6.1 6.1 16.7 7.6 5.8 16.7 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase N-terminal NARP1 PF12569.8 KXH25672.1 - 6.3 5.6 28.8 7.9 5.3 28.8 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Presenilin PF01080.17 KXH25672.1 - 8.1 5.1 17.4 9.9 4.8 17.4 1.1 1 0 0 1 1 1 0 Presenilin DUF2151 PF10221.9 KXH25672.1 - 8.5 4.8 17.5 9.9 4.6 17.5 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator FancD2 PF14631.6 KXH25672.1 - 9.3 3.5 15.6 11 3.3 15.6 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease Tim54 PF11711.8 KXH25672.1 - 10 4.8 21.0 14 4.3 21.0 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Glyco_hydro_3_C PF01915.22 KXH25673.1 - 2.7e-44 151.6 0.0 4.5e-44 150.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 KXH25673.1 - 7.1e-28 96.5 0.8 5.9e-26 90.4 0.2 2.5 2 0 0 2 2 2 2 Fibronectin type III-like domain Glyco_hydro_3 PF00933.21 KXH25673.1 - 1.6e-24 86.9 0.2 2.1e-15 56.9 0.1 2.3 2 0 0 2 2 2 2 Glycosyl hydrolase family 3 N terminal domain Ank_4 PF13637.6 KXH25674.1 - 6.4e-20 71.3 3.0 1.7e-06 28.4 0.1 5.1 5 0 0 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXH25674.1 - 7.8e-20 70.7 7.2 3.6e-08 33.5 0.2 5.1 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXH25674.1 - 1.3e-14 54.5 4.3 2.6e-06 27.9 0.4 3.7 2 2 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXH25674.1 - 1.8e-14 52.4 3.3 0.01 16.3 0.1 5.4 4 1 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 KXH25674.1 - 8.8e-10 38.6 12.3 0.027 14.9 0.0 5.7 6 0 0 6 6 6 3 Ankyrin repeat F-box-like PF12937.7 KXH25674.1 - 0.00046 20.0 0.1 0.0017 18.2 0.1 2.0 1 1 0 1 1 1 1 F-box-like PilX_N PF14341.6 KXH25674.1 - 0.048 13.6 0.2 0.1 12.6 0.2 1.4 1 0 0 1 1 1 0 PilX N-terminal Peptidase_S9 PF00326.21 KXH25675.1 - 2e-15 56.9 0.0 2.6e-15 56.5 0.0 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 KXH25675.1 - 1.6e-06 28.2 0.0 2.1e-06 27.8 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.18 KXH25675.1 - 5e-05 23.0 0.0 0.00014 21.5 0.0 1.6 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 KXH25675.1 - 0.00051 19.8 0.0 0.13 11.9 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXH25675.1 - 0.0011 18.3 0.0 0.31 10.3 0.0 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 FSH1 PF03959.13 KXH25675.1 - 0.0076 15.9 0.0 0.015 15.0 0.0 1.4 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Peptidase_S15 PF02129.18 KXH25675.1 - 0.031 13.9 0.0 1.9 8.0 0.0 2.2 1 1 1 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Lamprin PF06403.11 KXH25675.1 - 0.034 14.1 0.7 0.1 12.5 0.1 2.0 2 0 0 2 2 2 0 Lamprin Say1_Mug180 PF10340.9 KXH25675.1 - 0.21 10.4 0.0 0.34 9.7 0.0 1.2 1 0 0 1 1 1 0 Steryl acetyl hydrolase Peroxidase_2 PF01328.17 KXH25676.1 - 1.1e-50 172.8 0.1 1.5e-50 172.3 0.1 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 ADH_zinc_N PF00107.26 KXH25716.1 - 0.01 15.8 0.0 0.016 15.2 0.0 1.2 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Fungal_trans PF04082.18 KXH25717.1 - 8.8e-24 83.9 0.1 1.5e-23 83.2 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain SUIM_assoc PF16619.5 KXH25717.1 - 0.023 14.7 0.5 0.056 13.5 0.5 1.6 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Gag_MA PF01140.19 KXH25717.1 - 0.08 12.7 0.2 0.18 11.5 0.2 1.5 1 0 0 1 1 1 0 Matrix protein (MA), p15 Sgf11_N PF18519.1 KXH25717.1 - 0.37 10.4 3.7 0.43 10.2 1.4 2.1 2 0 0 2 2 2 0 SAGA-associated factor 11 N-terminal domain DUF3455 PF11937.8 KXH25745.1 - 3.9e-41 141.1 0.0 6.2e-41 140.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) DUF2990 PF11693.8 KXH25745.1 - 0.0022 18.1 4.6 0.04 14.1 3.0 2.9 2 1 0 2 2 2 1 Protein of unknown function (DUF2990) PSI_PsaJ PF01701.18 KXH25745.1 - 0.8 10.3 0.1 0.8 10.3 0.1 2.5 3 0 0 3 3 3 0 Photosystem I reaction centre subunit IX / PsaJ Podoplanin PF05808.11 KXH25746.1 - 0.29 11.2 1.4 0.6 10.2 1.4 1.4 1 0 0 1 1 1 0 Podoplanin Ribosomal_L22 PF00237.19 KXH25747.1 - 2.1e-41 140.4 0.0 3e-41 139.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e LTD PF00932.19 KXH25747.1 - 0.1 13.0 0.0 0.16 12.4 0.0 1.5 1 1 0 1 1 1 0 Lamin Tail Domain Fibrillarin PF01269.17 KXH25748.1 - 2.1e-101 337.8 0.0 2.6e-101 337.5 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 KXH25748.1 - 0.00018 21.3 0.1 0.00035 20.3 0.1 1.4 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Forkhead PF00250.18 KXH25821.1 - 1.8e-34 117.9 0.1 3.3e-34 117.0 0.1 1.5 1 0 0 1 1 1 1 Forkhead domain EF-hand_4 PF12763.7 KXH25822.1 - 1.7e-24 85.8 0.0 4e-12 46.0 0.0 2.4 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand DUF1720 PF08226.11 KXH25822.1 - 6.9e-06 26.4 142.8 0.00016 22.0 32.9 9.6 8 2 2 10 10 10 4 Domain of unknown function (DUF1720) EF-hand_1 PF00036.32 KXH25822.1 - 0.001 18.4 0.0 0.94 9.2 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 KXH25822.1 - 0.0046 17.4 2.2 1.8 9.1 0.0 3.3 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 KXH25822.1 - 0.069 13.1 0.1 41 4.5 0.0 3.3 3 0 0 3 3 3 0 EF-hand domain E3_binding PF02817.17 KXH25822.1 - 0.36 11.2 0.0 0.36 11.2 0.0 2.4 2 0 0 2 2 2 0 e3 binding domain LRR_1 PF00560.33 KXH25823.1 - 0.21 12.2 13.4 28 5.8 0.1 6.8 6 0 0 6 6 6 0 Leucine Rich Repeat LRR_4 PF12799.7 KXH25823.1 - 1.9 9.0 18.4 7.5 7.1 1.3 4.9 5 1 0 5 5 5 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KXH25823.1 - 5.6 7.3 17.7 6.9 7.0 0.9 6.1 7 0 0 7 7 7 0 Leucine Rich repeat FAD_binding_6 PF00970.24 KXH25824.1 - 3e-30 104.5 0.0 4.8e-30 103.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 KXH25824.1 - 9.9e-27 93.8 0.0 1.4e-26 93.2 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 KXH25824.1 - 0.00018 21.6 0.0 0.02 15.0 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 KXH25824.1 - 0.11 12.7 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain Pex16 PF08610.10 KXH25824.1 - 0.19 10.9 0.0 0.26 10.4 0.0 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) G-patch_2 PF12656.7 KXH25825.1 - 1.2e-14 54.1 1.2 1.2e-14 54.1 1.2 2.6 2 0 0 2 2 2 1 G-patch domain DUF2852 PF11014.8 KXH25825.1 - 0.15 12.2 1.7 0.42 10.8 1.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2852) Sugar_tr PF00083.24 KXH25826.1 - 2.2e-79 267.4 13.4 2.7e-79 267.1 13.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH25826.1 - 1.2e-14 54.0 20.7 1.2e-14 54.0 20.7 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily OppC_N PF12911.7 KXH25826.1 - 0.018 15.0 1.7 0.043 13.8 0.2 2.4 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C DUF2568 PF10823.8 KXH25826.1 - 1.2 9.5 11.0 5 7.5 0.5 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2568) Phosphodiest PF01663.22 KXH25827.1 - 4.8e-15 56.0 0.1 7.8e-15 55.3 0.1 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KXH25827.1 - 1.7e-06 27.7 0.0 2.8e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.18 KXH25827.1 - 0.00059 19.3 0.8 0.0017 17.8 0.8 1.7 2 0 0 2 2 2 1 Metalloenzyme superfamily NTF2 PF02136.20 KXH25828.1 - 3.3e-25 89.0 0.4 5.1e-25 88.4 0.4 1.3 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.22 KXH25828.1 - 5.7e-05 22.9 0.1 0.0001 22.0 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DbpA PF03880.15 KXH25828.1 - 0.091 12.8 0.0 0.23 11.5 0.0 1.7 1 0 0 1 1 1 0 DbpA RNA binding domain RRM_3 PF08777.11 KXH25828.1 - 0.098 12.7 1.4 0.25 11.4 0.0 2.4 2 0 0 2 2 2 0 RNA binding motif PI-PLC-X PF00388.19 KXH25876.1 - 3.9e-07 29.7 0.0 6.2e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Dynamin_N PF00350.23 KXH25877.1 - 4.7e-07 30.0 0.0 9.3e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Dynamin family RsgA_GTPase PF03193.16 KXH25877.1 - 3.8e-05 23.6 0.0 7.2e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase MMR_HSR1 PF01926.23 KXH25877.1 - 0.00026 21.0 0.0 0.00052 20.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KXH25877.1 - 0.00084 19.8 0.1 0.002 18.5 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 KXH25877.1 - 0.001 19.6 0.0 0.0021 18.6 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_22 PF13401.6 KXH25877.1 - 0.011 15.9 0.0 0.029 14.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain Roc PF08477.13 KXH25877.1 - 0.015 15.5 0.0 0.029 14.6 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AIG1 PF04548.16 KXH25877.1 - 0.021 14.2 0.0 0.031 13.6 0.0 1.3 1 0 0 1 1 1 0 AIG1 family Septin PF00735.18 KXH25877.1 - 0.087 12.1 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Septin PilJ PF13675.6 KXH25877.1 - 0.1 12.6 0.3 1.6 8.8 0.1 2.3 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term AAA_7 PF12775.7 KXH25877.1 - 0.12 11.9 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Lant_dehydr_C PF14028.6 KXH25878.1 - 0.027 14.0 0.2 0.15 11.5 0.1 1.9 2 0 0 2 2 2 0 Lantibiotic biosynthesis dehydratase C-term CdvA PF18822.1 KXH25878.1 - 0.29 11.0 3.8 15 5.5 0.3 3.1 2 1 1 3 3 3 0 CdvA-like coiled-coil domain FeoB_Cyto PF17910.1 KXH25878.1 - 0.41 11.2 2.3 4.7 7.8 0.2 2.4 2 1 0 2 2 2 0 FeoB cytosolic helical domain Baculo_PEP_C PF04513.12 KXH25878.1 - 0.87 9.6 4.5 11 6.0 0.5 2.6 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Pectate_lyase PF03211.13 KXH25879.1 - 1.2e-83 279.7 13.9 1.4e-83 279.5 13.9 1.0 1 0 0 1 1 1 1 Pectate lyase TPR_2 PF07719.17 KXH25880.1 - 3.4e-14 51.7 12.3 7.1e-05 22.6 0.0 6.1 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_1 PF00515.28 KXH25880.1 - 3.3e-09 36.2 8.4 0.0015 18.3 0.0 6.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 KXH25880.1 - 9.6e-08 31.7 1.2 0.3 11.4 0.0 5.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 KXH25880.1 - 1.1e-07 32.4 12.2 0.28 11.9 0.0 6.3 7 1 1 8 8 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 KXH25880.1 - 8.1e-07 29.5 5.6 0.0018 18.8 0.0 4.4 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 KXH25880.1 - 2.8e-06 26.9 0.0 2.1 8.1 0.0 6.1 6 0 0 6 6 6 1 TPR repeat TPR_12 PF13424.6 KXH25880.1 - 6.9e-05 23.1 4.9 0.01 16.1 0.7 4.4 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 KXH25880.1 - 0.0001 22.4 1.9 19 5.9 0.0 5.9 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 KXH25880.1 - 0.00054 19.8 1.6 3.1 8.0 0.1 4.1 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_4 PF07721.14 KXH25880.1 - 0.0041 17.6 13.7 0.13 13.0 1.6 4.7 6 0 0 6 6 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 KXH25880.1 - 0.02 15.7 11.1 11 7.1 0.1 6.9 7 1 1 8 8 6 0 Tetratricopeptide repeat TPR_10 PF13374.6 KXH25880.1 - 0.76 9.7 6.8 48 4.0 0.2 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 KXH25880.1 - 1.7 9.4 5.6 1.2e+02 3.6 0.0 5.2 6 0 0 6 6 6 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KXH25880.1 - 5.1 7.4 6.2 61 3.9 0.3 4.2 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 AA_permease_2 PF13520.6 KXH25881.1 - 3.8e-51 174.2 48.7 4.4e-51 174.0 48.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXH25881.1 - 7.4e-23 80.9 42.1 1e-22 80.4 42.1 1.1 1 0 0 1 1 1 1 Amino acid permease p450 PF00067.22 KXH25882.1 - 1.1e-36 126.6 0.0 1.4e-36 126.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ThrE_2 PF12821.7 KXH25882.1 - 0.15 12.2 0.1 0.56 10.3 0.0 1.9 2 0 0 2 2 2 0 Threonine/Serine exporter, ThrE Peptidase_S9 PF00326.21 KXH25883.1 - 2.1e-48 164.6 1.0 3.9e-48 163.7 1.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family DPPIV_N PF00930.21 KXH25883.1 - 2.2e-40 138.5 0.6 4.1e-40 137.6 0.6 1.4 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region VHL PF01847.16 KXH25883.1 - 1.8e-08 34.2 0.0 4.2e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 VHL beta domain Peptidase_S15 PF02129.18 KXH25883.1 - 6.2e-08 32.6 0.9 6.6e-07 29.2 0.8 2.2 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.18 KXH25883.1 - 0.00017 21.2 0.0 0.00034 20.2 0.0 1.4 1 0 0 1 1 1 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 KXH25883.1 - 0.032 13.5 0.1 0.35 10.1 0.0 2.3 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Esterase PF00756.20 KXH25883.1 - 0.037 13.7 0.1 0.094 12.3 0.1 1.6 1 0 0 1 1 1 0 Putative esterase Transglut_C PF00927.22 KXH25883.1 - 0.19 11.9 0.0 0.37 11.0 0.0 1.4 1 0 0 1 1 1 0 Transglutaminase family, C-terminal ig like domain Abhydrolase_3 PF07859.13 KXH25883.1 - 0.25 11.2 1.0 4.6 7.0 0.6 2.2 1 1 1 2 2 2 0 alpha/beta hydrolase fold Fungal_trans_2 PF11951.8 KXH25884.1 - 9.5e-26 90.5 0.5 4.9e-12 45.4 0.1 2.1 1 1 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH25884.1 - 1e-07 31.9 14.2 2.2e-07 30.9 14.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PhyH PF05721.13 KXH25885.1 - 1e-23 84.7 0.0 1.4e-23 84.2 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) MFS_1 PF07690.16 KXH25886.1 - 9e-35 120.2 40.6 9e-35 120.2 40.6 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Internalin_N PF12354.8 KXH25886.1 - 0.13 12.3 1.2 0.6 10.2 0.3 2.5 2 0 0 2 2 2 0 Bacterial adhesion/invasion protein N terminal PPR_2 PF13041.6 KXH25887.1 - 0.00062 19.9 0.0 11 6.3 0.0 5.1 5 1 1 6 6 6 1 PPR repeat family PPR PF01535.20 KXH25887.1 - 0.22 11.9 3.2 14 6.2 0.0 4.7 6 0 0 6 6 6 0 PPR repeat LSM PF01423.22 KXH25888.1 - 1.3e-16 60.0 0.0 1.8e-16 59.6 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KXH25888.1 - 0.014 15.5 0.0 0.019 15.1 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain Sulfatase PF00884.23 KXH25889.1 - 3.4e-61 207.3 0.5 3.4e-61 207.3 0.5 1.5 2 0 0 2 2 2 1 Sulfatase Phosphodiest PF01663.22 KXH25889.1 - 4.9e-06 26.4 0.2 1e-05 25.3 0.2 1.4 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4976 PF16347.5 KXH25889.1 - 0.0018 18.5 0.0 0.0042 17.3 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4976) DUF229 PF02995.17 KXH25889.1 - 0.0028 16.3 0.0 0.0047 15.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) DUF1501 PF07394.12 KXH25889.1 - 0.037 13.1 0.0 0.06 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) MFS_1 PF07690.16 KXH25890.1 - 9.1e-37 126.8 34.2 9.1e-37 126.8 34.2 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH25890.1 - 6.1e-13 48.4 18.3 2e-12 46.8 18.3 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 KXH25890.1 - 2.3e-08 32.9 4.4 4.1e-08 32.1 4.4 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sas10 PF09368.10 KXH25903.1 - 2e-30 105.1 10.8 2e-30 105.1 10.8 3.3 3 1 0 3 3 3 1 Sas10 C-terminal domain Vps51 PF08700.11 KXH25904.1 - 3.8e-12 46.1 0.0 1.5e-11 44.2 0.0 2.1 1 0 0 1 1 1 1 Vps51/Vps67 CaMKII_AD PF08332.10 KXH25904.1 - 0.028 14.6 0.0 0.067 13.3 0.0 1.6 1 0 0 1 1 1 0 Calcium/calmodulin dependent protein kinase II association domain RR_TM4-6 PF06459.12 KXH25904.1 - 0.63 9.8 3.5 1.2 8.9 3.5 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 ECH_1 PF00378.20 KXH25905.1 - 8.4e-25 87.5 0.0 1.6e-24 86.6 0.0 1.4 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXH25905.1 - 9.6e-15 54.9 0.0 1.1e-14 54.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase RNA_pol_I_A49 PF06870.12 KXH25906.1 - 1.3e-101 340.3 0.2 1.6e-101 340.0 0.2 1.1 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor ADSL_C PF10397.9 KXH25906.1 - 0.042 14.4 0.0 0.12 12.9 0.0 1.7 1 0 0 1 1 1 0 Adenylosuccinate lyase C-terminus OsmC PF02566.19 KXH25907.1 - 1.1e-15 57.9 0.0 1.7e-15 57.3 0.0 1.3 1 0 0 1 1 1 1 OsmC-like protein Pkinase PF00069.25 KXH25936.1 - 7.6e-35 120.5 0.0 1.5e-18 67.1 0.0 2.3 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXH25936.1 - 1e-15 57.7 0.0 8.1e-09 35.1 0.0 2.5 3 0 0 3 3 3 2 Protein tyrosine kinase RIO1 PF01163.22 KXH25936.1 - 0.012 15.3 0.1 0.026 14.1 0.0 1.6 2 0 0 2 2 2 0 RIO1 family EcKinase PF02958.20 KXH25936.1 - 0.24 10.7 0.0 9.1 5.5 0.0 2.2 2 0 0 2 2 2 0 Ecdysteroid kinase Peptidase_S8 PF00082.22 KXH25937.1 - 2.1e-38 132.3 1.7 3.8e-38 131.4 1.7 1.4 1 0 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 KXH25937.1 - 2.6e-09 37.8 0.0 5.5e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 Fn3-like domain DUF4232 PF14016.6 KXH25937.1 - 0.98 9.6 7.9 0.096 12.8 0.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF4232) Trypsin PF00089.26 KXH25938.1 - 1.2e-12 48.1 0.1 1.8e-12 47.6 0.1 1.1 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 KXH25938.1 - 4.3e-07 30.9 0.2 2.2e-06 28.6 0.1 1.9 2 0 0 2 2 2 1 Trypsin-like peptidase domain MFS_1 PF07690.16 KXH25939.1 - 8e-33 113.8 31.6 1.3e-32 113.1 31.6 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF2303 PF10065.9 KXH25939.1 - 0.44 9.7 1.4 0.42 9.7 0.2 1.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2303) Phage_holin_3_6 PF07332.11 KXH25939.1 - 2.6 8.1 5.9 0.41 10.7 0.2 2.6 2 1 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III FMO-like PF00743.19 KXH25941.1 - 2.1e-17 62.8 0.0 2.7e-16 59.1 0.0 2.0 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KXH25941.1 - 8.9e-10 38.7 0.8 4.1e-09 36.6 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXH25941.1 - 2.6e-09 36.7 0.0 2.8e-08 33.3 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXH25941.1 - 3.7e-09 36.7 0.5 2.5e-07 30.8 0.1 3.4 3 1 0 3 3 3 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 KXH25941.1 - 2.4e-07 30.2 0.0 3.3e-05 23.2 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KXH25941.1 - 1.2e-06 28.0 0.4 0.005 16.1 0.0 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KXH25941.1 - 0.00021 20.8 0.1 0.00064 19.1 0.0 1.8 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 KXH25941.1 - 0.0026 18.3 0.0 4.6 7.9 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXH25941.1 - 0.0052 16.4 0.2 0.047 13.3 0.1 2.5 2 1 1 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.17 KXH25941.1 - 0.0056 15.9 0.0 0.013 14.8 0.0 1.6 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 KXH25941.1 - 0.024 13.9 0.1 0.042 13.1 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 KXH25941.1 - 0.029 13.1 0.1 0.046 12.4 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein GST_N_4 PF17172.4 KXH25943.1 - 9.5e-22 77.6 0.1 5.9e-20 71.9 0.0 2.6 2 1 0 2 2 2 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 KXH25943.1 - 1.7e-11 43.7 0.1 1.4e-10 40.8 0.0 2.3 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 KXH25943.1 - 6.5e-11 42.6 0.3 3.5e-10 40.3 0.0 2.0 1 1 1 2 2 2 1 Outer mitochondrial membrane transport complex protein GST_C_2 PF13410.6 KXH25943.1 - 0.018 15.0 0.4 0.063 13.3 0.4 2.0 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain SAM35 PF10806.8 KXH25943.1 - 0.028 14.7 0.0 0.052 13.8 0.0 1.4 1 0 0 1 1 1 0 SAM35, subunit of SAM coomplex Adeno_PIX PF03955.14 KXH25944.1 - 0.011 15.9 0.3 0.018 15.2 0.3 1.3 1 0 0 1 1 1 0 Adenovirus hexon-associated protein (IX) adh_short_C2 PF13561.6 KXH25946.1 - 1.2e-45 156.0 0.0 1.5e-45 155.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXH25946.1 - 2.9e-35 121.5 0.0 3.8e-35 121.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Herpes_UL36 PF03586.13 KXH25946.1 - 0.13 11.6 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL36 tegument protein SUR7 PF06687.12 KXH25947.1 - 4.5e-31 108.1 15.2 5.7e-31 107.8 15.2 1.1 1 0 0 1 1 1 1 SUR7/PalI family HEV_ORF1 PF02444.16 KXH25947.1 - 0.13 12.8 1.6 0.22 12.1 0.2 2.1 2 0 0 2 2 2 0 Hepatitis E virus ORF-2 (Putative capsid protein) DUF4834 PF16118.5 KXH25947.1 - 0.27 12.2 2.2 19 6.3 0.0 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4834) Phage_holin_3_2 PF04550.12 KXH25947.1 - 3.4 8.3 8.5 0.6 10.7 2.3 2.4 2 0 0 2 2 2 0 Phage holin family 2 2-Hacid_dh_C PF02826.19 KXH25948.1 - 2.6e-55 186.5 0.0 6.4e-55 185.3 0.0 1.6 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KXH25948.1 - 2e-32 111.7 0.0 2.5e-32 111.4 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KXH25948.1 - 9.5e-08 32.4 0.0 5.8e-07 29.8 0.0 2.0 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase CoA_binding_2 PF13380.6 KXH25948.1 - 0.00081 19.9 0.0 0.002 18.6 0.0 1.6 1 0 0 1 1 1 1 CoA binding domain AlaDh_PNT_C PF01262.21 KXH25948.1 - 0.0012 18.2 0.4 0.084 12.2 0.4 2.4 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain IlvN PF07991.12 KXH25948.1 - 0.0019 17.8 0.0 0.013 15.0 0.0 2.0 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain HisG_C PF08029.11 KXH25948.1 - 0.032 14.4 0.1 0.075 13.2 0.0 1.6 2 0 0 2 2 2 0 HisG, C-terminal domain AdoHcyase_NAD PF00670.21 KXH25948.1 - 0.048 13.7 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Semialdhyde_dh PF01118.24 KXH25948.1 - 0.11 12.9 0.3 16 6.0 0.1 2.4 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 KXH25948.1 - 0.19 12.6 3.7 1.9 9.4 0.1 3.1 2 1 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold 3HCDH_N PF02737.18 KXH25948.1 - 0.2 11.5 0.7 0.86 9.5 0.0 2.2 2 1 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MFS_1 PF07690.16 KXH25949.1 - 2.2e-40 138.7 32.7 2.2e-40 138.7 32.7 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KXH25949.1 - 2.5e-07 29.5 4.8 3.9e-07 28.9 4.8 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KXH25949.1 - 1.3e-05 24.3 26.2 6.8e-05 21.9 26.1 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter DUF2178 PF09946.9 KXH25949.1 - 3.3 7.9 8.9 2.6 8.3 3.3 2.9 2 1 0 2 2 2 0 Predicted membrane protein (DUF2178) RSN1_7TM PF02714.15 KXH25950.1 - 5.9e-67 225.9 26.7 9.8e-67 225.1 26.7 1.3 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 KXH25950.1 - 5.2e-39 134.3 0.2 2.7e-38 132.0 0.0 2.0 2 0 0 2 2 2 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 KXH25950.1 - 1e-35 122.8 0.6 1e-35 122.8 0.6 2.3 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport TPR_MLP1_2 PF07926.12 KXH25952.1 - 0.0087 16.1 10.0 0.0087 16.1 10.0 4.0 1 1 2 3 3 3 1 TPR/MLP1/MLP2-like protein BST2 PF16716.5 KXH25952.1 - 0.025 15.2 7.4 0.025 15.2 7.4 4.8 2 2 2 4 4 4 0 Bone marrow stromal antigen 2 Carbpep_Y_N PF05388.11 KXH25952.1 - 0.047 14.2 0.8 0.047 14.2 0.8 3.2 2 1 1 3 3 3 0 Carboxypeptidase Y pro-peptide CALCOCO1 PF07888.11 KXH25952.1 - 0.22 10.4 46.9 0.34 9.7 10.9 2.8 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like FlaC_arch PF05377.11 KXH25952.1 - 0.23 11.9 20.9 0.27 11.6 2.5 5.1 5 0 0 5 5 5 0 Flagella accessory protein C (FlaC) Trimer_CC PF08954.11 KXH25952.1 - 0.25 10.9 6.9 7.3 6.2 0.2 3.6 3 0 0 3 3 3 0 Trimerisation motif Fib_alpha PF08702.10 KXH25952.1 - 0.78 9.9 20.1 1.4 9.1 5.2 2.8 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Baculo_PEP_C PF04513.12 KXH25952.1 - 1.1 9.3 15.1 0.64 10.1 2.7 2.9 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus TMCO5 PF14992.6 KXH25952.1 - 1.2 8.7 41.3 1.5 8.3 10.8 2.2 2 0 0 2 2 2 0 TMCO5 family DUF3584 PF12128.8 KXH25952.1 - 1.4 6.4 45.1 0.03 11.9 11.8 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF3584) Fmp27_WPPW PF10359.9 KXH25952.1 - 2.6 6.8 25.7 1.3 7.8 11.4 2.3 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain ApoO PF09769.9 KXH25952.1 - 3.9 7.4 8.6 23 5.0 0.2 3.6 2 2 2 4 4 4 0 Apolipoprotein O AAA_13 PF13166.6 KXH25952.1 - 4.7 5.7 45.7 0.12 11.0 8.7 2.2 1 1 1 2 2 2 0 AAA domain Ax_dynein_light PF10211.9 KXH25952.1 - 7.1 6.5 46.7 0.077 12.9 10.7 3.5 2 1 1 3 3 3 0 Axonemal dynein light chain Sugar_tr PF00083.24 KXH25953.1 - 6.7e-123 410.9 18.7 1.2e-122 410.1 18.7 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH25953.1 - 1.7e-29 102.9 52.1 1.5e-24 86.6 29.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_5 PF05631.14 KXH25953.1 - 0.0013 17.7 1.1 0.0038 16.2 0.3 2.1 2 0 0 2 2 2 1 Sugar-tranasporters, 12 TM ALMT PF11744.8 KXH25953.1 - 0.6 8.9 1.6 1.1 8.0 1.6 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter Fungal_trans_2 PF11951.8 KXH25954.1 - 5.1e-09 35.4 0.3 7.7e-09 34.8 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain GFO_IDH_MocA PF01408.22 KXH25955.1 - 1.9e-25 90.0 0.6 8e-25 88.0 0.3 2.0 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KXH25955.1 - 1e-05 25.5 0.0 2.1e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_2 PF03446.15 KXH25955.1 - 0.015 15.5 0.1 0.037 14.2 0.1 1.8 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase CoA_binding PF02629.19 KXH25955.1 - 0.076 13.7 0.0 0.3 11.8 0.0 2.0 2 0 0 2 2 2 0 CoA binding domain MutS_V PF00488.21 KXH25957.1 - 3.9e-59 199.8 1.3 6.4e-59 199.1 1.3 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KXH25957.1 - 8.4e-27 94.6 0.8 8.4e-27 94.6 0.8 2.1 2 0 0 2 2 2 1 MutS domain III MutS_II PF05188.17 KXH25957.1 - 0.00014 22.2 0.0 0.00033 20.9 0.0 1.7 1 0 0 1 1 1 1 MutS domain II AAA_27 PF13514.6 KXH25957.1 - 0.074 12.6 0.1 0.54 9.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain FAR1 PF03101.15 KXH25958.1 - 6.8e-05 23.5 2.6 6.8e-05 23.5 2.6 3.0 2 1 0 2 2 2 1 FAR1 DNA-binding domain PAT1 PF09770.9 KXH25958.1 - 1 7.5 52.6 1.7 6.8 52.6 1.4 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 WD40 PF00400.32 KXH25959.1 - 4.6e-55 182.3 36.1 1.7e-10 41.3 0.5 9.2 8 1 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXH25959.1 - 2e-19 69.7 7.9 0.0024 18.1 0.0 6.1 3 3 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KXH25959.1 - 5.6e-09 35.4 0.0 0.29 10.0 0.0 4.7 3 2 2 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KXH25959.1 - 1.2e-06 28.6 0.4 0.00081 19.3 0.0 3.3 3 1 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KXH25959.1 - 0.005 15.6 3.4 0.6 8.7 0.1 3.9 4 1 0 4 4 4 2 Nucleoporin Nup120/160 PD40 PF07676.12 KXH25959.1 - 0.0092 15.9 0.0 5.4 7.1 0.0 3.0 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat NLE PF08154.12 KXH25959.1 - 0.018 15.6 0.0 0.039 14.5 0.0 1.5 1 0 0 1 1 1 0 NLE (NUC135) domain DinB PF05163.12 KXH25959.1 - 0.05 13.5 0.1 0.089 12.7 0.1 1.3 1 0 0 1 1 1 0 DinB family WD40_like PF17005.5 KXH25959.1 - 0.3 10.4 0.0 27 4.0 0.0 3.1 4 0 0 4 4 4 0 WD40-like domain Glyco_transf_20 PF00982.21 KXH25960.1 - 3.8e-165 550.2 0.0 5.2e-165 549.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 KXH25960.1 - 6.5e-45 153.1 0.0 2.2e-44 151.3 0.0 1.8 2 0 0 2 2 2 1 Trehalose-phosphatase Glyco_transf_5 PF08323.11 KXH25960.1 - 0.075 12.7 0.3 0.15 11.7 0.3 1.4 1 0 0 1 1 1 0 Starch synthase catalytic domain Cupin_2 PF07883.11 KXH25961.1 - 7.7e-07 28.7 0.3 1.1e-06 28.3 0.3 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 KXH25961.1 - 0.001 18.7 0.0 0.0014 18.2 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_6 PF12852.7 KXH25961.1 - 0.024 14.3 0.0 0.053 13.2 0.0 1.5 1 1 1 2 2 2 0 Cupin AraC_binding PF02311.19 KXH25961.1 - 0.026 14.4 0.1 0.049 13.5 0.1 1.6 1 1 0 1 1 1 0 AraC-like ligand binding domain Cupin_3 PF05899.12 KXH25961.1 - 0.058 13.1 0.0 0.085 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF861) ARD PF03079.14 KXH25961.1 - 0.11 12.7 0.0 0.14 12.3 0.0 1.2 1 0 0 1 1 1 0 ARD/ARD' family FMO-like PF00743.19 KXH25962.1 - 2.8e-19 69.0 0.0 6.8e-19 67.7 0.0 1.6 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KXH25962.1 - 4.3e-14 52.5 0.0 3.5e-13 49.5 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXH25962.1 - 5.8e-14 52.1 0.0 4e-13 49.4 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KXH25962.1 - 2.3e-10 40.2 0.0 7.7e-06 25.3 0.0 2.3 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KXH25962.1 - 7.6e-08 32.3 0.0 4.3e-05 23.3 0.0 2.7 2 1 1 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KXH25962.1 - 6.9e-07 29.4 0.0 7.6e-06 26.0 0.0 2.6 2 1 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KXH25962.1 - 6.9e-07 28.8 0.0 1.3e-05 24.6 0.0 2.4 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXH25962.1 - 0.0014 19.1 0.0 0.062 13.9 0.0 3.1 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXH25962.1 - 0.0043 16.3 0.0 0.011 15.0 0.0 1.6 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 KXH25962.1 - 0.017 14.2 0.0 0.4 9.7 0.0 2.4 2 1 0 2 2 2 0 Lycopene cyclase protein Shikimate_DH PF01488.20 KXH25962.1 - 0.054 13.6 0.0 3.5 7.7 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DUF2524 PF10732.9 KXH25962.1 - 0.075 13.3 1.2 0.17 12.2 1.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2524) 2-Hacid_dh_C PF02826.19 KXH25962.1 - 0.18 11.2 0.2 15 4.9 0.0 2.5 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Ring_hydroxyl_A PF00848.19 KXH25963.1 - 2.2e-15 57.2 3.8 3.7e-11 43.4 0.1 2.3 1 1 1 2 2 2 2 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.26 KXH25963.1 - 1.8e-14 53.4 0.0 3.1e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Fungal_trans PF04082.18 KXH25964.1 - 0.0051 15.9 0.3 0.014 14.4 0.3 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Aminotran_4 PF01063.19 KXH25965.1 - 4.1e-21 75.9 0.0 5.1e-21 75.6 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV K_trans PF02705.16 KXH25966.1 - 2.4e-182 607.2 17.1 2.8e-182 607.0 17.1 1.0 1 0 0 1 1 1 1 K+ potassium transporter Fungal_trans PF04082.18 KXH25967.1 - 3.7e-18 65.5 0.0 6.1e-18 64.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glucos_trans_II PF14264.6 KXH25967.1 - 0.092 12.1 0.6 4.1 6.7 0.2 2.1 2 0 0 2 2 2 0 Glucosyl transferase GtrII Sugar_tr PF00083.24 KXH25968.1 - 1.5e-111 373.4 20.1 1.9e-111 373.1 20.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH25968.1 - 1.9e-22 79.7 23.3 3.2e-15 55.9 0.9 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF4131 PF13567.6 KXH25968.1 - 1.4 8.5 0.0 1.4 8.5 0.0 2.7 3 1 0 3 3 3 0 Domain of unknown function (DUF4131) Dynamin_M PF01031.20 KXH25969.1 - 5.2e-26 91.5 1.7 9e-15 54.6 0.0 3.8 4 0 0 4 4 4 2 Dynamin central region Dynamin_N PF00350.23 KXH25969.1 - 4e-19 69.3 0.0 1.5e-18 67.4 0.0 2.0 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 KXH25969.1 - 5.8e-05 23.1 0.2 0.00088 19.3 0.1 2.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_28 PF13521.6 KXH25969.1 - 0.0011 19.3 5.2 0.0013 19.0 0.0 3.4 4 0 0 4 4 4 1 AAA domain FeoB_N PF02421.18 KXH25969.1 - 0.0029 17.1 0.1 0.94 9.0 0.0 2.8 3 0 0 3 3 3 2 Ferrous iron transport protein B Roc PF08477.13 KXH25969.1 - 0.052 13.8 0.1 1.6 9.0 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase GED PF02212.18 KXH25969.1 - 0.14 12.3 0.4 1.4 9.1 0.1 2.7 2 0 0 2 2 2 0 Dynamin GTPase effector domain GMP_synt_C PF00958.22 KXH25969.1 - 0.14 12.2 0.2 0.68 10.0 0.0 2.2 2 0 0 2 2 2 0 GMP synthase C terminal domain Sugar_tr PF00083.24 KXH25970.1 - 1.2e-90 304.6 25.2 1.4e-90 304.3 25.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH25970.1 - 1.7e-19 70.0 23.3 1.7e-19 70.0 23.3 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily MFMR PF07777.11 KXH25971.1 - 0.087 13.3 1.0 0.15 12.6 1.0 1.6 1 1 0 1 1 1 0 G-box binding protein MFMR Glyco_hydro_3_C PF01915.22 KXH25972.1 - 3.6e-55 187.1 0.0 5.9e-55 186.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KXH25972.1 - 1.8e-53 182.0 0.0 3e-53 181.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KXH25972.1 - 5.4e-19 68.1 0.0 1.4e-18 66.8 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 KXH25972.1 - 7.7e-16 58.2 0.0 1.5e-15 57.3 0.0 1.4 1 0 0 1 1 1 1 PA14 domain adh_short_C2 PF13561.6 KXH25973.1 - 1.4e-39 136.0 3.6 1.7e-39 135.8 3.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXH25973.1 - 6.2e-37 127.0 3.1 7.7e-37 126.6 3.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXH25973.1 - 7.3e-11 42.3 0.2 1.1e-10 41.8 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXH25973.1 - 0.0015 18.0 0.6 0.0081 15.6 0.6 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family MOSC PF03473.17 KXH25974.1 - 1.6e-25 89.6 0.0 3.4e-25 88.5 0.0 1.6 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 KXH25974.1 - 2.4e-09 37.1 0.0 5.3e-05 23.1 0.0 2.5 2 0 0 2 2 2 2 MOSC N-terminal beta barrel domain Fungal_trans_2 PF11951.8 KXH25975.1 - 1.7e-31 109.4 1.0 2.3e-31 109.0 1.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH25975.1 - 6.1e-10 39.1 11.7 6.1e-10 39.1 11.7 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldedh PF00171.22 KXH25976.1 - 2.8e-184 612.9 0.2 3.2e-184 612.8 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Rotamase_2 PF13145.6 KXH25976.1 - 0.15 12.9 0.3 0.34 11.8 0.3 1.6 1 0 0 1 1 1 0 PPIC-type PPIASE domain Ribonuc_L-PSP PF01042.21 KXH25977.1 - 8.1e-21 74.3 0.0 9.3e-21 74.1 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Hit1_C PF18268.1 KXH25977.1 - 0.072 13.2 0.0 0.14 12.4 0.0 1.4 1 1 0 1 1 1 0 Hit1 C-terminal ADH_N PF08240.12 KXH25978.1 - 4.9e-30 103.6 3.4 7.8e-30 103.0 3.4 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXH25978.1 - 1.1e-25 90.1 0.8 2.2e-25 89.1 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KXH25978.1 - 1.9e-07 30.8 0.2 3.7e-07 29.9 0.2 1.4 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KXH25978.1 - 1.3e-06 29.5 0.0 2.8e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KXH25978.1 - 1.2e-05 24.7 2.0 1.8e-05 24.1 1.1 1.6 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_N_assoc PF13823.6 KXH25978.1 - 0.0009 19.1 0.0 0.0017 18.3 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated NAS PF03059.16 KXH25978.1 - 0.064 12.6 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Nicotianamine synthase protein F420_oxidored PF03807.17 KXH25978.1 - 0.11 13.1 0.1 0.65 10.6 0.1 2.2 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent SET PF00856.28 KXH25979.1 - 2e-16 60.9 0.1 2.4e-15 57.3 0.0 2.7 2 2 0 2 2 2 1 SET domain TPR_2 PF07719.17 KXH25979.1 - 2.4e-08 33.5 4.3 9.1e-07 28.5 1.1 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 KXH25979.1 - 1.5e-06 27.8 5.3 0.0003 20.5 0.5 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KXH25979.1 - 4.4e-05 23.4 4.6 0.00018 21.4 0.2 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 KXH25979.1 - 0.0033 17.7 3.1 0.0083 16.4 3.1 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 KXH25979.1 - 0.011 16.5 2.8 0.011 16.5 0.2 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat SAF PF08666.12 KXH25979.1 - 0.028 15.0 0.0 5.8 7.6 0.0 2.8 2 0 0 2 2 2 0 SAF domain DMAP1 PF05499.12 KXH25979.1 - 0.12 12.2 0.2 0.12 12.2 0.2 2.2 2 0 0 2 2 2 0 DNA methyltransferase 1-associated protein 1 (DMAP1) DUF3042 PF11240.8 KXH25980.1 - 7.8 6.6 9.3 6.4 6.9 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3042) Cyclase PF04199.13 KXH25981.1 - 2.6e-15 56.9 0.2 3.5e-15 56.4 0.2 1.2 1 0 0 1 1 1 1 Putative cyclase NAD_binding_8 PF13450.6 KXH25982.1 - 2.9e-05 24.2 0.0 0.00016 21.8 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXH25982.1 - 0.00044 19.6 0.0 0.051 12.8 0.0 2.8 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXH25982.1 - 0.0019 18.2 0.0 0.15 12.1 0.0 2.9 3 0 0 3 3 3 1 FAD-NAD(P)-binding 2-Hacid_dh_C PF02826.19 KXH25982.1 - 0.0041 16.5 0.0 0.0089 15.4 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 KXH25982.1 - 0.014 15.9 0.1 5 7.8 0.0 3.0 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 KXH25982.1 - 0.024 14.7 0.0 0.093 12.8 0.0 1.9 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FMO-like PF00743.19 KXH25982.1 - 0.21 10.0 0.0 1.3 7.3 0.0 2.0 2 0 0 2 2 2 0 Flavin-binding monooxygenase-like GMC_oxred_N PF00732.19 KXH25984.1 - 6.8e-27 94.6 0.0 1.1e-26 94.0 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXH25984.1 - 7.1e-15 55.8 0.1 1.3e-14 54.9 0.1 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KXH25984.1 - 2.4e-07 30.2 0.0 0.0044 16.2 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 KXH25984.1 - 0.00019 21.1 2.5 0.00094 18.9 2.3 2.1 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KXH25984.1 - 0.00044 19.7 0.0 0.08 12.3 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXH25984.1 - 0.00055 20.1 0.0 0.0017 18.6 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KXH25984.1 - 0.0013 19.3 0.0 1.4 9.5 0.0 2.7 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXH25984.1 - 0.0034 16.7 0.1 0.0085 15.4 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXH25984.1 - 0.0061 15.3 0.0 0.027 13.2 0.0 1.9 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.19 KXH25984.1 - 0.0079 15.5 0.0 0.021 14.1 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 KXH25984.1 - 0.036 13.1 0.0 0.052 12.6 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein ABC_tran PF00005.27 KXH25985.1 - 5.3e-38 130.6 0.0 1.3e-18 67.9 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KXH25985.1 - 2.8e-33 115.7 18.0 8.8e-28 97.7 9.1 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_29 PF13555.6 KXH25985.1 - 1.4e-07 31.1 1.6 0.0099 15.6 0.2 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 KXH25985.1 - 7.4e-07 29.3 0.7 0.19 11.5 0.0 3.4 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system T2SSE PF00437.20 KXH25985.1 - 1.3e-06 27.7 0.3 0.007 15.5 0.1 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein SMC_N PF02463.19 KXH25985.1 - 3e-06 26.8 0.2 0.65 9.4 0.0 3.2 2 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KXH25985.1 - 3.3e-06 27.4 0.6 0.014 15.7 0.0 2.9 2 1 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KXH25985.1 - 1.6e-05 24.9 0.0 0.072 13.0 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 KXH25985.1 - 0.0001 22.8 1.2 0.027 14.8 0.0 3.0 3 0 0 3 3 2 1 AAA ATPase domain AAA_33 PF13671.6 KXH25985.1 - 0.00032 20.9 0.0 0.094 12.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KXH25985.1 - 0.00037 20.1 0.4 1.3 8.6 0.0 3.3 3 0 0 3 3 3 1 AAA domain FtsK_SpoIIIE PF01580.18 KXH25985.1 - 0.00046 19.6 0.1 0.82 9.0 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family TsaE PF02367.17 KXH25985.1 - 0.00096 19.2 0.3 0.34 10.9 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE MMR_HSR1 PF01926.23 KXH25985.1 - 0.0015 18.6 0.9 1.3 9.1 0.1 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.6 KXH25985.1 - 0.0023 18.5 5.7 0.39 11.2 0.3 2.6 3 0 0 3 3 2 2 AAA domain AAA_18 PF13238.6 KXH25985.1 - 0.0062 17.1 1.0 0.77 10.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KXH25985.1 - 0.011 16.2 0.0 3.3 8.1 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_30 PF13604.6 KXH25985.1 - 0.011 15.4 0.8 0.11 12.2 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KXH25985.1 - 0.015 14.8 0.2 3.7 7.0 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_15 PF13175.6 KXH25985.1 - 0.038 13.7 1.3 7.5 6.2 0.1 2.6 3 0 0 3 3 2 0 AAA ATPase domain DUF87 PF01935.17 KXH25985.1 - 0.049 13.7 3.8 0.056 13.5 0.2 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain NACHT PF05729.12 KXH25985.1 - 0.061 13.2 4.5 0.68 9.8 0.2 2.9 3 0 0 3 3 2 0 NACHT domain Pox_A32 PF04665.12 KXH25985.1 - 0.098 12.1 0.8 6.8 6.1 0.1 2.5 2 0 0 2 2 2 0 Poxvirus A32 protein ATPase_2 PF01637.18 KXH25985.1 - 0.12 12.3 0.1 3.7 7.4 0.0 2.3 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea NB-ARC PF00931.22 KXH25985.1 - 0.16 11.2 2.9 3.3 6.8 0.1 2.8 2 1 0 2 2 2 0 NB-ARC domain PduV-EutP PF10662.9 KXH25985.1 - 0.27 11.0 3.9 2 8.1 0.4 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.19 KXH25985.1 - 0.83 9.2 6.6 0.45 10.1 1.5 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.14 KXH25985.1 - 1.5 8.7 3.3 3.9 7.4 0.5 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.6 KXH25985.1 - 1.9 8.8 5.9 3.5 7.9 2.1 2.9 2 1 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 KXH25985.1 - 2.2 8.1 6.9 7.8 6.4 0.1 3.0 3 0 0 3 3 3 0 NTPase FAD_binding_4 PF01565.23 KXH25987.1 - 1.2e-22 80.1 1.7 1.9e-22 79.5 1.7 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KXH25987.1 - 0.0058 16.7 0.0 0.012 15.7 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like RRM_1 PF00076.22 KXH25990.1 - 3.9e-46 154.8 0.0 1.5e-16 59.9 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KXH25990.1 - 4e-05 23.5 0.1 0.0025 17.8 0.1 3.0 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 KXH25990.1 - 7.5e-05 22.5 0.0 0.057 13.3 0.0 3.1 3 0 0 3 3 3 1 Occluded RNA-recognition motif RRM_7 PF16367.5 KXH25990.1 - 0.0001 22.3 0.1 0.059 13.5 0.0 3.0 3 0 0 3 3 3 2 RNA recognition motif RRM_3 PF08777.11 KXH25990.1 - 0.00021 21.3 0.0 0.0019 18.2 0.0 2.3 3 0 0 3 3 3 1 RNA binding motif RRM_5 PF13893.6 KXH25990.1 - 0.035 13.7 0.0 0.12 11.9 0.0 1.8 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ecm29 PF13001.7 KXH25992.1 - 6.3e-128 427.6 0.0 1e-126 423.6 0.0 2.8 3 0 0 3 3 3 1 Proteasome stabiliser HEAT PF02985.22 KXH25992.1 - 0.00012 22.0 5.2 2.6 8.5 0.0 7.1 7 0 0 7 7 7 2 HEAT repeat IFRD PF05004.13 KXH25992.1 - 0.085 12.0 0.5 3.3 6.7 0.0 3.7 5 0 0 5 5 5 0 Interferon-related developmental regulator (IFRD) Rpp20 PF12328.8 KXH25992.1 - 0.1 12.6 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 Rpp20 subunit of nuclear RNase MRP and P Gemin6 PF06372.12 KXH25992.1 - 0.14 11.7 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 Gemin6 protein Thioredoxin_7 PF13899.6 KXH25993.1 - 3.6e-17 62.3 0.0 7.1e-17 61.4 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like UBA_4 PF14555.6 KXH25993.1 - 6.1e-16 58.0 0.6 1.3e-15 56.9 0.6 1.6 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.20 KXH25993.1 - 1.8e-06 28.0 0.0 3.3e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 UBX domain Thioredox_DsbH PF03190.15 KXH25993.1 - 0.01 15.8 0.0 0.018 15.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF255 Pkinase PF00069.25 KXH25995.1 - 7.4e-69 232.0 0.0 1.3e-68 231.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXH25995.1 - 9.1e-51 172.6 0.0 1.5e-50 171.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXH25995.1 - 0.00051 18.9 0.0 0.00092 18.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KXH25995.1 - 0.031 13.6 0.0 0.073 12.4 0.0 1.5 1 0 0 1 1 1 0 Kinase-like DUF347 PF03988.12 KXH25996.1 - 0.047 13.9 0.0 0.12 12.6 0.0 1.7 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) EthD PF07110.11 KXH26028.1 - 0.0082 17.3 0.0 0.016 16.4 0.0 1.5 1 0 0 1 1 1 1 EthD domain 5_nucleotid_C PF02872.18 KXH26031.1 - 2.9e-34 118.6 0.2 7e-34 117.3 0.2 1.6 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 KXH26031.1 - 6.2e-10 39.9 1.0 3.7e-09 37.4 0.5 2.1 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase F-box-like PF12937.7 KXH26032.1 - 0.034 14.0 0.0 0.08 12.8 0.0 1.6 1 0 0 1 1 1 0 F-box-like Sugar_tr PF00083.24 KXH26033.1 - 3.4e-75 253.6 26.8 3.9e-75 253.4 26.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH26033.1 - 1.2e-14 54.0 44.8 2.2e-10 40.0 20.0 2.4 1 1 2 3 3 3 2 Major Facilitator Superfamily DUF3792 PF12670.7 KXH26033.1 - 8 6.7 21.6 6.2 7.0 2.1 4.0 3 1 1 4 4 4 0 Protein of unknown function (DUF3792) Pkinase PF00069.25 KXH26034.1 - 4.4e-11 42.6 0.0 7e-11 42.0 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.23 KXH26034.1 - 0.00011 22.3 0.0 0.00013 22.0 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KXH26034.1 - 0.0021 17.4 0.0 0.0027 17.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KXH26034.1 - 0.0034 17.0 0.2 0.0045 16.6 0.0 1.4 2 0 0 2 2 2 1 Choline/ethanolamine kinase RIO1 PF01163.22 KXH26034.1 - 0.0081 15.8 0.0 0.017 14.7 0.0 1.4 1 1 0 1 1 1 1 RIO1 family Pkinase_Tyr PF07714.17 KXH26034.1 - 0.027 13.8 0.0 0.027 13.7 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase Kinase-like PF14531.6 KXH26034.1 - 0.041 13.2 0.0 0.051 12.9 0.0 1.1 1 0 0 1 1 1 0 Kinase-like PTPA PF03095.15 KXH26039.1 - 2.6e-112 375.2 0.0 3.1e-112 374.9 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Cutinase PF01083.22 KXH26040.1 - 7.7e-46 156.3 1.5 9.2e-46 156.0 1.5 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 KXH26040.1 - 1.3e-05 24.9 0.1 1.8e-05 24.4 0.1 1.2 1 0 0 1 1 1 1 PE-PPE domain VirJ PF06057.11 KXH26040.1 - 0.042 13.7 0.0 0.061 13.2 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Abhydrolase_2 PF02230.16 KXH26040.1 - 0.047 13.5 0.0 0.18 11.6 0.0 1.8 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.20 KXH26040.1 - 0.054 13.1 0.0 0.078 12.6 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold AT_hook PF02178.19 KXH26041.1 - 5.2 7.3 10.0 0.19 11.7 2.3 2.7 2 0 0 2 2 2 0 AT hook motif p450 PF00067.22 KXH26042.1 - 2.2e-60 204.7 0.0 2.8e-60 204.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_4 PF01565.23 KXH26043.1 - 2.4e-21 75.9 4.0 1.2e-20 73.7 4.0 2.0 1 1 0 1 1 1 1 FAD binding domain BBE PF08031.12 KXH26043.1 - 0.17 12.0 0.1 0.38 10.9 0.1 1.5 1 0 0 1 1 1 0 Berberine and berberine like Sec2p PF06428.11 KXH26044.1 - 0.00037 20.4 4.9 0.00037 20.4 4.9 15.2 2 1 9 14 14 14 3 GDP/GTP exchange factor Sec2p Filament PF00038.21 KXH26044.1 - 0.003 17.2 172.1 0.053 13.1 37.6 7.0 1 1 6 7 7 7 5 Intermediate filament protein TPR_MLP1_2 PF07926.12 KXH26044.1 - 0.0094 16.0 27.9 0.0094 16.0 27.9 11.5 1 1 12 13 13 13 4 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 KXH26044.1 - 0.027 13.4 204.0 0.023 13.6 30.5 8.5 1 1 7 8 8 8 0 Spc7 kinetochore protein TetR_C_17 PF17922.1 KXH26044.1 - 3.4 7.8 8.5 3.1 7.9 1.1 3.6 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain NPC1_N PF16414.5 KXH26045.1 - 6.3e-84 281.4 9.3 8.8e-84 280.9 9.3 1.2 1 0 0 1 1 1 1 Niemann-Pick C1 N terminus Patched PF02460.18 KXH26045.1 - 1.9e-75 254.6 15.1 5.8e-48 163.6 0.6 2.6 3 0 0 3 3 3 2 Patched family Sterol-sensing PF12349.8 KXH26045.1 - 1.9e-51 174.0 6.5 1.9e-51 174.0 6.5 2.9 2 1 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation Folate_rec PF03024.14 KXH26045.1 - 3.4e-05 23.8 1.9 7.1e-05 22.7 1.9 1.4 1 0 0 1 1 1 1 Folate receptor family MMPL PF03176.15 KXH26045.1 - 3.9e-05 22.7 33.6 0.00068 18.7 9.9 3.0 3 0 0 3 3 3 2 MMPL family UvrD_C PF13361.6 KXH26046.1 - 5.2e-65 220.1 0.0 4.9e-64 216.9 0.0 2.0 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.21 KXH26046.1 - 8.8e-63 212.7 0.0 1.1e-60 205.8 0.0 2.6 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_19 PF13245.6 KXH26046.1 - 1.9e-30 106.1 0.0 4.5e-30 104.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 KXH26046.1 - 1.8e-14 53.3 0.0 3.5e-14 52.4 0.0 1.5 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 KXH26046.1 - 6.7e-07 29.2 0.3 0.014 15.1 0.1 2.4 2 0 0 2 2 2 2 AAA domain AAA_12 PF13087.6 KXH26046.1 - 2.1e-05 24.3 0.0 0.00029 20.5 0.0 2.4 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 KXH26046.1 - 5.1e-05 23.1 0.1 1.2 8.8 0.0 3.3 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DUF3517 PF12030.8 KXH26046.1 - 0.019 13.9 0.0 0.18 10.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3517) DUF1631 PF07793.11 KXH26046.1 - 0.33 9.3 5.4 0.57 8.5 5.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) CcmD PF04995.14 KXH26048.1 - 0.0045 17.0 0.5 0.0088 16.1 0.5 1.4 1 0 0 1 1 1 1 Heme exporter protein D (CcmD) DUF2014 PF09427.10 KXH26049.1 - 6.1e-113 376.5 7.8 9.1e-113 376.0 7.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2014) HLH PF00010.26 KXH26049.1 - 6.1e-17 61.3 0.9 1.8e-16 59.8 0.9 1.9 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain SUIM_assoc PF16619.5 KXH26049.1 - 0.12 12.4 4.1 0.51 10.4 4.1 2.0 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Spt5_N PF11942.8 KXH26049.1 - 1.8 9.6 8.2 0.26 12.3 2.9 2.3 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Ceramidase_alk PF04734.13 KXH26050.1 - 2.7e-222 738.9 0.0 3.2e-222 738.6 0.0 1.1 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 KXH26050.1 - 9.7e-58 194.7 0.1 1.7e-57 193.9 0.1 1.4 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal HET PF06985.11 KXH26051.1 - 6e-27 94.8 2.4 2.2e-26 93.0 0.1 2.3 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) DUF4448 PF14610.6 KXH26052.1 - 0.011 15.5 0.0 0.017 14.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Amnionless PF14828.6 KXH26052.1 - 0.026 13.4 0.0 0.031 13.1 0.0 1.1 1 0 0 1 1 1 0 Amnionless MHYT PF03707.16 KXH26052.1 - 0.054 13.7 0.2 0.12 12.6 0.2 1.6 1 0 0 1 1 1 0 Bacterial signalling protein N terminal repeat DUF3617 PF12276.8 KXH26052.1 - 0.078 13.3 2.5 0.11 12.8 2.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3617) SKG6 PF08693.10 KXH26052.1 - 4.4 6.8 5.5 16 5.0 5.5 2.0 1 1 0 1 1 1 0 Transmembrane alpha-helix domain G_glu_transpept PF01019.21 KXH26053.1 - 1.8e-168 561.5 0.1 2.2e-168 561.2 0.1 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase RrnaAD PF00398.20 KXH26054.1 - 0.0008 18.6 0.0 0.0012 18.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase PRMT5 PF05185.16 KXH26054.1 - 0.057 13.3 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Methyltransf_32 PF13679.6 KXH26054.1 - 0.062 13.3 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain adh_short_C2 PF13561.6 KXH26055.1 - 4.4e-56 190.1 1.1 5e-56 189.9 1.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXH26055.1 - 3.5e-47 160.4 0.0 4.3e-47 160.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXH26055.1 - 1.5e-11 44.6 0.1 2.2e-11 44.0 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXH26055.1 - 0.022 14.2 0.0 0.03 13.8 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Pyr_redox PF00070.27 KXH26055.1 - 0.055 14.0 0.0 0.1 13.2 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase THF_DHG_CYH_C PF02882.19 KXH26055.1 - 0.061 12.7 0.0 0.34 10.2 0.0 2.0 1 1 1 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain MBOAT_2 PF13813.6 KXH26056.1 - 2.3e-10 40.6 1.2 2.3e-10 40.6 1.2 2.6 4 0 0 4 4 4 1 Membrane bound O-acyl transferase family DUF1176 PF06674.11 KXH26056.1 - 0.15 11.5 0.4 0.22 11.0 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1176) FAD_binding_4 PF01565.23 KXH26057.1 - 1.8e-20 73.1 1.8 3.6e-20 72.1 1.8 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KXH26057.1 - 1.7e-08 34.4 0.1 3.8e-08 33.3 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like Tyrosinase PF00264.20 KXH26060.1 - 2.5e-37 129.3 0.0 3.3e-37 128.9 0.0 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase DUF2206 PF09971.9 KXH26061.1 - 2.9 6.6 7.2 0.41 9.4 0.3 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2206) DAO PF01266.24 KXH26062.1 - 1.6e-07 31.3 1.2 0.0033 17.1 0.2 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KXH26062.1 - 2.2e-07 30.3 0.6 6.4e-06 25.5 0.9 2.1 2 0 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.19 KXH26062.1 - 8.3e-07 28.6 5.9 0.0035 16.7 0.5 2.8 2 1 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 KXH26062.1 - 1.4e-06 27.8 0.1 0.00044 19.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXH26062.1 - 4.4e-06 25.7 0.2 0.0019 17.0 0.4 2.1 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_8 PF13450.6 KXH26062.1 - 2e-05 24.7 0.0 6e-05 23.2 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KXH26062.1 - 0.00024 20.4 0.0 0.00042 19.7 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KXH26062.1 - 0.00058 19.3 0.4 0.0011 18.4 0.4 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 KXH26062.1 - 0.006 15.7 0.3 0.0099 15.0 0.3 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 KXH26062.1 - 0.008 15.3 0.4 1.1 8.2 0.2 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 KXH26062.1 - 0.012 14.9 0.0 0.019 14.2 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 KXH26062.1 - 0.037 14.6 0.3 0.17 12.4 0.8 1.8 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KXH26062.1 - 0.081 11.8 0.6 3.7 6.3 0.0 2.2 2 0 0 2 2 2 0 Tryptophan halogenase Thi4 PF01946.17 KXH26062.1 - 0.14 11.4 0.1 0.24 10.6 0.1 1.3 1 0 0 1 1 1 0 Thi4 family 3HCDH_N PF02737.18 KXH26062.1 - 0.17 11.7 0.0 0.28 11.0 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Fungal_trans_2 PF11951.8 KXH26064.1 - 5.8e-12 45.1 0.3 1.6e-11 43.7 0.1 1.7 1 1 1 2 2 2 1 Fungal specific transcription factor domain Abhydrolase_6 PF12697.7 KXH26065.1 - 3.7e-09 37.5 1.0 4.9e-09 37.1 1.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 KXH26065.1 - 4.1e-09 36.3 0.1 2.2e-08 33.9 0.1 2.1 2 1 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 KXH26065.1 - 1.9e-08 34.2 0.3 1.4e-07 31.4 0.1 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXH26065.1 - 6.4e-07 28.9 0.2 1.2e-06 28.0 0.2 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 AXE1 PF05448.12 KXH26065.1 - 6.5e-06 25.0 0.2 1.1e-05 24.3 0.2 1.3 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Peptidase_S15 PF02129.18 KXH26065.1 - 2.2e-05 24.2 0.9 4.4e-05 23.2 0.9 1.7 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) BAAT_C PF08840.11 KXH26065.1 - 0.00014 21.9 0.0 0.00029 20.8 0.0 1.6 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.21 KXH26065.1 - 0.00051 19.6 0.5 0.0014 18.1 0.2 1.9 2 0 0 2 2 2 1 Prolyl oligopeptidase family adh_short PF00106.25 KXH26066.1 - 7e-40 136.6 0.0 9.2e-40 136.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXH26066.1 - 2.3e-26 92.8 0.0 3.2e-26 92.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH26066.1 - 3.1e-10 40.2 0.0 5.2e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXH26066.1 - 7.2e-06 25.6 0.0 1e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 KXH26066.1 - 1.1e-05 25.0 0.0 1.4e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.6 KXH26066.1 - 0.00063 19.7 0.0 0.00076 19.4 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KXH26066.1 - 0.0053 16.3 0.0 0.01 15.4 0.0 1.6 2 0 0 2 2 2 1 NmrA-like family ADH_zinc_N PF00107.26 KXH26066.1 - 0.11 12.5 1.2 0.48 10.4 1.2 2.0 1 1 0 1 1 1 0 Zinc-binding dehydrogenase CDH-cyt PF16010.5 KXH26067.1 - 1.2e-49 168.5 0.0 1.4e-49 168.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase Flavoprotein PF02441.19 KXH26069.1 - 2.4e-18 66.4 0.0 3.9e-18 65.7 0.0 1.3 1 0 0 1 1 1 1 Flavoprotein Ank_4 PF13637.6 KXH26069.1 - 0.017 15.7 0.0 0.16 12.6 0.0 2.7 3 1 0 3 3 3 0 Ankyrin repeats (many copies) Flavodoxin_2 PF02525.17 KXH26069.1 - 0.13 11.9 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Flavodoxin-like fold Ank_2 PF12796.7 KXH26072.1 - 2.1e-19 69.9 0.0 3.6e-07 30.7 0.0 4.3 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.30 KXH26072.1 - 9.6e-19 66.9 0.5 0.0063 16.9 0.0 5.7 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 KXH26072.1 - 1.1e-17 63.9 0.2 1.4e-06 28.5 0.1 3.7 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXH26072.1 - 2.3e-16 58.2 0.2 0.0016 18.7 0.0 6.9 7 1 0 7 7 7 4 Ankyrin repeat Ank_4 PF13637.6 KXH26072.1 - 4.2e-16 59.1 0.0 0.016 15.8 0.0 6.4 4 2 4 8 8 8 5 Ankyrin repeats (many copies) TsaE PF02367.17 KXH26073.1 - 0.067 13.2 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MFS_1 PF07690.16 KXH26074.1 - 2.2e-30 105.8 35.3 2.2e-30 105.8 35.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH26074.1 - 0.0007 18.6 18.4 0.0007 18.6 18.4 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter Fungal_trans PF04082.18 KXH26075.1 - 9.3e-25 87.2 0.0 2e-24 86.1 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Aldo_ket_red PF00248.21 KXH26077.1 - 9.5e-49 166.2 0.0 1.1e-48 166.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family OPT PF03169.15 KXH26079.1 - 8.3e-164 546.6 56.6 9.4e-164 546.4 56.6 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein ADH_zinc_N PF00107.26 KXH26080.1 - 2.1e-15 56.8 0.0 3.3e-15 56.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXH26080.1 - 3.3e-09 37.9 0.0 5.2e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXH26080.1 - 6.6e-06 26.0 0.4 1.9e-05 24.5 0.3 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Pox_A12 PF04651.13 KXH26080.1 - 0.049 13.7 0.1 0.089 12.9 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A12 protein GxGYxYP_C PF14323.6 KXH26081.1 - 3.2e-58 197.4 0.0 6.3e-58 196.5 0.0 1.5 1 0 0 1 1 1 1 GxGYxYP putative glycoside hydrolase C-terminal domain GxGYxYP_N PF16216.5 KXH26081.1 - 1.3e-40 139.8 0.0 3.1e-24 86.4 0.0 2.2 2 0 0 2 2 2 2 GxGYxY sequence motif in domain of unknown function N-terminal Invasin_D3 PF09134.10 KXH26081.1 - 0.032 14.6 0.2 0.11 12.8 0.2 1.9 1 0 0 1 1 1 0 Invasin, domain 3 PHO4 PF01384.20 KXH26082.1 - 3.1e-114 381.5 17.7 3.5e-114 381.3 17.7 1.0 1 0 0 1 1 1 1 Phosphate transporter family NAD_binding_10 PF13460.6 KXH26083.1 - 2.9e-16 59.9 0.0 3.9e-16 59.5 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KXH26083.1 - 2.1e-15 56.9 0.0 3.1e-15 56.4 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family GFO_IDH_MocA PF01408.22 KXH26083.1 - 9e-06 26.5 0.1 1.9e-05 25.5 0.1 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.24 KXH26083.1 - 0.00011 22.6 0.1 0.00032 21.1 0.0 1.8 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.21 KXH26083.1 - 0.00048 19.7 0.3 0.0011 18.5 0.1 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.20 KXH26083.1 - 0.0011 19.1 0.0 0.0019 18.3 0.0 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus NAD_binding_4 PF07993.12 KXH26083.1 - 0.002 17.4 0.0 0.003 16.8 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein F420_oxidored PF03807.17 KXH26083.1 - 0.18 12.4 0.2 0.41 11.3 0.1 1.7 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent MFS_1 PF07690.16 KXH26084.1 - 2.1e-18 66.4 32.3 1.1e-17 64.1 6.2 2.7 2 1 1 3 3 3 3 Major Facilitator Superfamily p450 PF00067.22 KXH26085.1 - 1e-49 169.5 0.0 2.5e-29 102.4 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 DUF2235 PF09994.9 KXH26086.1 - 1.1e-78 264.6 1.1 7e-78 261.9 1.1 2.1 1 1 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Ribonuclease PF00545.20 KXH26087.1 - 3.2e-09 37.4 0.0 4.5e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 ribonuclease NmrA PF05368.13 KXH26088.1 - 4.7e-32 111.4 0.0 2.8e-31 108.9 0.0 1.8 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXH26088.1 - 5.4e-09 36.2 0.0 8.1e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Hira PF07569.11 KXH26089.1 - 5.2e-85 284.7 0.0 1.4e-84 283.3 0.0 1.8 2 0 0 2 2 2 1 TUP1-like enhancer of split WD40 PF00400.32 KXH26089.1 - 2.1e-29 101.1 22.2 4.9e-05 24.0 0.0 8.2 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXH26089.1 - 6.5e-13 48.8 0.0 0.16 12.3 0.0 6.0 5 1 1 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain HIRA_B PF09453.10 KXH26089.1 - 7.4e-10 38.4 0.4 2e-09 37.0 0.4 1.8 1 0 0 1 1 1 1 HIRA B motif PD40 PF07676.12 KXH26089.1 - 2e-05 24.4 0.6 5.5 7.0 0.3 4.6 4 0 0 4 4 4 3 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KXH26089.1 - 6e-05 22.2 3.0 0.76 8.7 0.2 4.7 2 2 3 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein IKI3 PF04762.12 KXH26089.1 - 0.011 13.8 0.0 0.067 11.2 0.0 2.1 3 0 0 3 3 3 0 IKI3 family Lebercilin PF15619.6 KXH26093.1 - 0.0019 17.9 13.8 0.0019 17.9 13.8 5.4 1 1 3 5 5 5 1 Ciliary protein causing Leber congenital amaurosis disease Spc7 PF08317.11 KXH26093.1 - 0.0054 15.7 12.5 0.0054 15.7 12.5 4.6 2 1 2 4 4 4 2 Spc7 kinetochore protein SHE3 PF17078.5 KXH26093.1 - 0.008 15.9 8.5 0.008 15.9 8.5 4.8 1 1 2 4 4 4 1 SWI5-dependent HO expression protein 3 DUF1664 PF07889.12 KXH26093.1 - 0.4 10.7 40.5 0.12 12.4 1.5 6.4 3 1 4 7 7 7 0 Protein of unknown function (DUF1664) ArAE_2_N PF10337.9 KXH26094.1 - 2.7e-36 125.6 3.1 2.7e-36 125.6 3.1 3.8 2 2 1 3 3 3 1 Putative ER transporter, 6TM, N-terminal FUSC_2 PF13515.6 KXH26094.1 - 5e-18 65.5 19.1 5e-18 65.5 19.1 3.0 2 1 0 2 2 2 1 Fusaric acid resistance protein-like ArAE_2 PF10334.9 KXH26094.1 - 2.6e-06 27.4 1.1 1.2e-05 25.3 0.3 2.3 2 1 0 2 2 2 1 Aromatic acid exporter family member 2 Velvet PF11754.8 KXH26095.1 - 4.9e-38 131.5 10.3 1.8e-28 100.2 0.1 3.2 2 1 1 3 3 3 2 Velvet factor 2-Hacid_dh_C PF02826.19 KXH26111.1 - 4.8e-57 192.2 0.0 7.5e-57 191.6 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KXH26111.1 - 3.2e-20 72.2 0.0 3.6e-20 72.0 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KXH26111.1 - 0.0048 17.1 0.1 0.0084 16.3 0.1 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase FYVE PF01363.21 KXH26120.1 - 0.00049 20.2 1.7 0.00096 19.2 1.7 1.5 1 0 0 1 1 1 1 FYVE zinc finger UPF0167 PF03691.14 KXH26120.1 - 0.073 12.9 4.5 0.16 11.7 4.5 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0167) FYVE_2 PF02318.16 KXH26120.1 - 0.17 12.1 5.0 0.37 11.0 5.0 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger zf-B_box PF00643.24 KXH26120.1 - 2 8.6 6.9 3.9 7.7 6.9 1.4 1 0 0 1 1 1 0 B-box zinc finger C1_2 PF03107.16 KXH26120.1 - 8.8 6.7 8.2 18 5.7 8.2 1.5 1 0 0 1 1 1 0 C1 domain Apt1 PF10351.9 KXH26120.1 - 9.8 4.9 24.3 1.8 7.4 7.6 2.2 2 0 0 2 2 2 0 Golgi-body localisation protein domain MBOAT_2 PF13813.6 KXH26122.1 - 7.3e-16 58.2 8.1 2.7e-15 56.4 6.4 2.4 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family CorA PF01544.18 KXH26123.1 - 0.13 11.6 4.6 0.38 10.0 4.6 1.8 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein Telomerase_RBD PF12009.8 KXH26124.1 - 6e-50 168.8 0.0 2.2e-49 167.0 0.0 2.0 2 0 0 2 2 2 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.27 KXH26124.1 - 1.4e-11 44.3 0.0 7e-08 32.2 0.0 2.6 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) F-box_5 PF18511.1 KXH26124.1 - 0.016 14.7 0.2 0.039 13.5 0.2 1.7 1 0 0 1 1 1 0 F-box IreB PF06135.12 KXH26124.1 - 0.096 12.9 0.0 0.29 11.3 0.0 1.8 1 0 0 1 1 1 0 IreB regulatory phosphoprotein RhoGEF PF00621.20 KXH26125.1 - 8.1e-32 110.9 0.0 1.8e-31 109.8 0.0 1.6 1 0 0 1 1 1 1 RhoGEF domain BAR PF03114.18 KXH26125.1 - 1.2e-10 41.4 0.0 3.5e-10 39.9 0.0 1.8 1 0 0 1 1 1 1 BAR domain LPD13 PF18825.1 KXH26125.1 - 0.06 13.1 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Large polyvalent protein-associated domain 13 Seryl_tRNA_N PF02403.22 KXH26125.1 - 0.2 11.9 4.7 6.7 7.0 0.2 2.6 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Velvet PF11754.8 KXH26126.1 - 9.9e-91 304.1 4.6 2.4e-90 302.9 4.6 1.6 1 1 0 1 1 1 1 Velvet factor HLH PF00010.26 KXH26127.1 - 4.8e-15 55.3 1.4 1.3e-14 53.9 1.4 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Pcc1 PF09341.10 KXH26128.1 - 2.6e-31 107.6 0.6 4e-31 107.0 0.6 1.3 1 0 0 1 1 1 1 Transcription factor Pcc1 DSPn PF14671.6 KXH26129.1 - 1.3e-41 142.4 0.0 2.8e-39 134.8 0.0 2.7 2 1 0 2 2 2 2 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 KXH26129.1 - 4.8e-16 58.8 0.0 1e-15 57.7 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KXH26129.1 - 4e-06 26.6 0.0 9.3e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase SH3BGR PF04908.15 KXH26132.1 - 0.00035 20.7 0.0 0.003 17.7 0.0 2.7 1 1 1 2 2 2 1 SH3-binding, glutamic acid-rich protein Abhydro_lipase PF04083.16 KXH26133.1 - 6.8e-19 67.2 0.0 1.4e-18 66.2 0.0 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 KXH26133.1 - 3.7e-06 26.8 0.0 1.1e-05 25.2 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXH26133.1 - 0.0071 15.6 0.0 0.028 13.7 0.0 1.9 2 0 0 2 2 2 1 Serine aminopeptidase, S33 AAA PF00004.29 KXH26134.1 - 1e-48 165.1 0.0 7.1e-43 146.2 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KXH26134.1 - 0.0001 22.7 0.1 0.022 15.2 0.0 3.1 1 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 KXH26134.1 - 0.00019 21.2 0.0 0.0006 19.6 0.0 1.8 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KXH26134.1 - 0.00074 19.8 0.1 0.038 14.3 0.0 2.8 2 1 1 3 3 3 1 AAA domain Parvo_NS1 PF01057.17 KXH26134.1 - 0.0008 18.6 0.0 0.0014 17.8 0.0 1.2 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_25 PF13481.6 KXH26134.1 - 0.0025 17.4 0.1 0.02 14.4 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_lid_3 PF17862.1 KXH26134.1 - 0.0031 17.3 5.1 0.25 11.2 0.4 2.9 3 0 0 3 3 3 2 AAA+ lid domain AAA_2 PF07724.14 KXH26134.1 - 0.0039 17.3 0.0 0.0093 16.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 KXH26134.1 - 0.0071 16.1 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.13 KXH26134.1 - 0.013 14.8 0.0 0.021 14.0 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain RNA_helicase PF00910.22 KXH26134.1 - 0.014 15.8 0.0 0.039 14.3 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.21 KXH26134.1 - 0.021 14.2 0.1 0.057 12.8 0.1 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ATPase PF06745.13 KXH26134.1 - 0.041 13.2 0.0 0.085 12.2 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_5 PF07728.14 KXH26134.1 - 0.045 13.8 0.0 0.14 12.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 KXH26134.1 - 0.051 13.1 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_18 PF13238.6 KXH26134.1 - 0.069 13.7 0.0 0.17 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 KXH26134.1 - 0.09 12.2 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_28 PF13521.6 KXH26134.1 - 0.097 12.9 0.0 0.25 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain Vps4_C PF09336.10 KXH26134.1 - 0.11 12.5 0.0 7.7 6.6 0.0 3.1 3 0 0 3 3 3 0 Vps4 C terminal oligomerisation domain Sigma54_activat PF00158.26 KXH26134.1 - 0.11 12.2 0.0 1.6 8.4 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_33 PF13671.6 KXH26134.1 - 0.12 12.5 0.0 0.4 10.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KXH26134.1 - 0.12 12.4 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATP11 PF06644.11 KXH26135.1 - 3.1e-105 351.9 0.2 3.7e-105 351.6 0.2 1.1 1 0 0 1 1 1 1 ATP11 protein CdiI_2 PF18593.1 KXH26135.1 - 0.12 13.0 0.9 0.25 12.0 0.2 1.9 2 0 0 2 2 2 0 CdiI immunity protein peroxidase PF00141.23 KXH26136.1 - 1.5e-47 162.2 0.0 2.5e-47 161.5 0.0 1.4 1 0 0 1 1 1 1 Peroxidase Suf PF05843.14 KXH26137.1 - 0.00013 22.1 13.3 0.011 15.7 0.0 3.9 2 2 1 3 3 3 3 Suppressor of forked protein (Suf) TPR_14 PF13428.6 KXH26137.1 - 0.0012 19.5 10.2 0.25 12.3 0.0 7.4 8 2 3 11 11 11 1 Tetratricopeptide repeat CBF PF03914.17 KXH26138.1 - 0.079 13.0 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 CBF/Mak21 family Syja_N PF02383.18 KXH26139.1 - 1.8e-73 247.7 0.0 3.9e-73 246.6 0.0 1.6 2 0 0 2 2 2 1 SacI homology domain Exo_endo_phos PF03372.23 KXH26139.1 - 3.8e-10 39.7 0.1 7.4e-10 38.7 0.1 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family 14-3-3 PF00244.20 KXH26141.1 - 1.2e-106 355.3 0.2 1.4e-106 355.0 0.2 1.1 1 0 0 1 1 1 1 14-3-3 protein Ribosomal_60s PF00428.19 KXH26141.1 - 0.019 15.5 7.7 0.064 13.8 4.3 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein TPR_19 PF14559.6 KXH26141.1 - 0.21 12.1 1.2 3.3 8.3 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat HTH_24 PF13412.6 KXH26195.1 - 0.014 15.0 0.0 0.019 14.5 0.0 1.2 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HERV-K_REC PF15695.5 KXH26195.1 - 0.12 12.4 0.0 0.16 12.1 0.0 1.1 1 0 0 1 1 1 0 Rec (regulator of expression encoded by corf) of HERV-K-113 Fungal_trans PF04082.18 KXH26196.1 - 6.7e-21 74.5 0.0 9.9e-21 73.9 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DAO PF01266.24 KXH26197.1 - 5.5e-27 95.3 0.1 1.3e-16 61.2 0.0 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXH26197.1 - 6.8e-05 23.0 0.0 0.00016 21.9 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KXH26197.1 - 0.00038 20.5 0.1 0.00091 19.2 0.1 1.6 1 0 0 1 1 1 1 FAD-NAD(P)-binding Thi4 PF01946.17 KXH26197.1 - 0.00065 19.0 0.0 0.0011 18.3 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 KXH26197.1 - 0.0066 15.7 0.1 0.0096 15.2 0.1 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase MCRA PF06100.11 KXH26197.1 - 0.011 14.6 0.0 0.016 14.0 0.0 1.1 1 0 0 1 1 1 0 MCRA family FAD_binding_2 PF00890.24 KXH26197.1 - 0.18 10.9 0.1 0.32 10.0 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 KXH26197.1 - 0.2 10.7 0.0 0.3 10.1 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein zf-trcl PF13451.6 KXH26197.1 - 2 8.4 5.1 0.92 9.5 1.7 2.1 2 0 0 2 2 2 0 Probable zinc-ribbon domain Hydrolase PF00702.26 KXH26198.1 - 0.00012 22.5 0.0 0.0002 21.7 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KXH26198.1 - 0.075 13.1 0.0 0.084 13.0 0.0 1.2 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase DUF730 PF05325.11 KXH26198.1 - 0.14 12.2 0.1 0.25 11.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF730) Aminotran_3 PF00202.21 KXH26199.1 - 2e-116 389.0 0.0 2.2e-116 388.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aldedh PF00171.22 KXH26200.1 - 6.2e-164 545.9 0.2 7e-164 545.7 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KXH26200.1 - 0.023 14.2 0.0 0.15 11.5 0.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1487) AstB PF04996.12 KXH26348.1 - 0.11 11.1 0.0 0.15 10.7 0.0 1.1 1 0 0 1 1 1 0 Succinylarginine dihydrolase Peptidase_S10 PF00450.22 KXH26349.1 - 3.8e-89 300.0 0.0 4.8e-89 299.6 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.7 KXH26349.1 - 0.00031 21.4 0.2 0.061 13.9 0.1 2.6 3 0 0 3 3 3 2 Alpha/beta hydrolase family CorA PF01544.18 KXH26350.1 - 2e-08 33.9 0.9 4.2e-08 32.9 0.1 2.0 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein AAA_13 PF13166.6 KXH26350.1 - 0.0056 15.4 3.1 1.1 7.8 0.0 2.1 2 0 0 2 2 2 2 AAA domain DUF2408 PF10303.9 KXH26350.1 - 0.89 10.1 3.6 8.2 7.0 3.6 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) SKG6 PF08693.10 KXH26351.1 - 2.9e-08 33.0 6.5 5e-08 32.2 6.5 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4448 PF14610.6 KXH26351.1 - 0.082 12.7 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) WD40 PF00400.32 KXH26352.1 - 5.3e-19 68.2 9.9 0.00083 20.1 0.0 8.1 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXH26352.1 - 1.1e-05 25.7 0.1 0.53 10.6 0.1 4.5 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Peroxidase_2 PF01328.17 KXH26354.1 - 4.6e-49 167.5 0.0 5.5e-49 167.2 0.0 1.0 1 0 0 1 1 1 1 Peroxidase, family 2 GRDP-like PF07173.12 KXH26355.1 - 1.5e-20 74.3 0.4 4.2e-17 63.1 0.1 2.7 2 1 1 3 3 3 2 Glycine-rich domain-containing protein-like Lep_receptor_Ig PF06328.11 KXH26355.1 - 0.16 11.9 0.5 1 9.4 0.3 2.1 2 0 0 2 2 2 0 Ig-like C2-type domain p450 PF00067.22 KXH26364.1 - 5.5e-36 124.3 0.0 6.1e-36 124.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans_2 PF11951.8 KXH26365.1 - 0.00043 19.2 0.4 0.0006 18.7 0.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH26365.1 - 0.11 12.6 4.0 0.29 11.3 4.0 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Thi4 PF01946.17 KXH26366.1 - 1e-116 388.2 0.4 1.2e-116 387.9 0.4 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 KXH26366.1 - 8.5e-08 32.2 4.5 7.9e-07 29.0 2.7 2.1 1 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXH26366.1 - 3.4e-05 24.0 0.5 8.3e-05 22.8 0.5 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KXH26366.1 - 6.5e-05 22.1 1.4 0.00025 20.2 0.9 1.9 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KXH26366.1 - 0.00024 20.4 0.3 0.00041 19.7 0.3 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXH26366.1 - 0.00071 18.8 4.3 0.0076 15.4 1.8 2.3 2 1 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.6 KXH26366.1 - 0.0024 17.9 1.7 0.0037 17.3 0.1 2.1 3 0 0 3 3 3 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 KXH26366.1 - 0.0063 15.8 0.1 0.011 15.1 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KXH26366.1 - 0.016 14.6 0.3 0.024 14.0 0.3 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KXH26366.1 - 0.032 13.5 0.0 0.051 12.8 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Mqo PF06039.15 KXH26366.1 - 0.25 9.9 0.8 0.47 9.0 0.0 1.8 3 0 0 3 3 3 0 Malate:quinone oxidoreductase (Mqo) Imm74 PF15603.6 KXH26367.1 - 0.0097 16.1 0.1 0.023 14.9 0.1 1.6 1 0 0 1 1 1 1 Immunity protein 74 PRKCSH PF07915.13 KXH26368.1 - 9.1e-20 71.5 0.2 9.1e-20 71.5 0.2 2.1 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.6 KXH26368.1 - 0.018 14.7 0.0 1.5 8.5 0.0 2.3 2 0 0 2 2 2 0 Glucosidase II beta subunit-like protein Fungal_trans PF04082.18 KXH26369.1 - 3.3e-08 32.9 0.7 6e-08 32.0 0.7 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH26369.1 - 6.1e-08 32.7 11.5 9.6e-08 32.0 11.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SUIM_assoc PF16619.5 KXH26369.1 - 4.3 7.5 28.8 0.052 13.6 1.5 4.7 5 0 0 5 5 5 0 Unstructured region C-term to UIM in Ataxin3 DEAD PF00270.29 KXH26370.1 - 1.6e-46 158.3 0.0 4.3e-44 150.4 0.0 2.2 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 KXH26370.1 - 3.3e-21 75.7 0.0 4.8e-19 68.7 0.0 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXH26370.1 - 2.7e-08 34.0 0.0 4.1e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.14 KXH26370.1 - 0.0042 17.0 0.0 0.0075 16.1 0.0 1.4 1 0 0 1 1 1 1 Helicase AAA_22 PF13401.6 KXH26370.1 - 0.058 13.7 0.8 0.87 9.9 1.3 2.6 2 2 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KXH26370.1 - 0.087 12.5 0.1 0.27 10.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 KXH26370.1 - 0.12 11.6 0.1 0.29 10.3 0.1 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Pkinase PF00069.25 KXH26371.1 - 8.1e-08 31.9 0.0 2.4e-07 30.4 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain VWA PF00092.28 KXH26371.1 - 0.0079 16.5 0.0 0.018 15.3 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain CorA PF01544.18 KXH26373.1 - 1.1 8.6 7.1 3.4 6.9 7.1 1.9 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein Abhydrolase_6 PF12697.7 KXH26376.1 - 7.4e-11 43.1 0.0 1.2e-10 42.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXH26376.1 - 9.4e-11 41.8 2.1 7.9e-09 35.5 1.3 2.5 2 1 0 3 3 3 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXH26376.1 - 2.1e-08 33.7 0.1 3.2e-08 33.1 0.1 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 KXH26376.1 - 0.044 13.9 0.0 0.072 13.2 0.0 1.5 1 1 0 1 1 1 0 Thioesterase domain ABC_tran PF00005.27 KXH26377.1 - 1.7e-43 148.4 0.0 2.2e-25 89.7 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KXH26377.1 - 4e-38 131.6 31.0 8.2e-21 74.9 8.7 3.6 4 0 0 4 4 3 3 ABC transporter transmembrane region SMC_N PF02463.19 KXH26377.1 - 6.3e-14 51.9 0.8 1.3e-05 24.7 0.0 4.2 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KXH26377.1 - 7.5e-08 33.1 0.1 2.9e-05 24.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 KXH26377.1 - 1.6e-07 31.5 0.3 0.013 15.3 0.0 4.3 3 1 1 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KXH26377.1 - 1.3e-06 28.0 0.2 0.041 13.6 0.2 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 KXH26377.1 - 3.9e-06 27.2 0.1 0.043 14.1 0.0 3.1 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KXH26377.1 - 4.6e-06 27.1 0.2 0.099 13.0 0.0 2.9 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KXH26377.1 - 0.00043 20.2 0.0 0.53 10.2 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase T2SSE PF00437.20 KXH26377.1 - 0.00074 18.7 0.1 1.4 7.9 0.3 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein NACHT PF05729.12 KXH26377.1 - 0.001 19.0 1.7 0.76 9.7 0.2 2.9 2 0 0 2 2 2 2 NACHT domain DUF87 PF01935.17 KXH26377.1 - 0.0015 18.6 2.7 0.015 15.4 0.4 2.4 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_25 PF13481.6 KXH26377.1 - 0.0017 18.0 0.5 0.051 13.1 0.1 2.5 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 KXH26377.1 - 0.0019 17.8 0.2 0.16 11.6 0.1 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 KXH26377.1 - 0.002 18.2 0.0 1.2 9.3 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA PF00004.29 KXH26377.1 - 0.0044 17.4 0.1 10 6.5 0.0 3.7 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.6 KXH26377.1 - 0.0076 16.5 0.0 1.3 9.3 0.0 3.0 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 KXH26377.1 - 0.01 15.5 0.2 4.4 7.0 0.0 2.9 2 1 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KXH26377.1 - 0.015 14.6 0.2 3.8 6.7 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin ATPase_2 PF01637.18 KXH26377.1 - 0.03 14.2 0.0 0.23 11.4 0.0 2.2 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea TrwB_AAD_bind PF10412.9 KXH26377.1 - 0.059 12.3 0.1 3.7 6.3 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain FtsK_SpoIIIE PF01580.18 KXH26377.1 - 0.065 12.6 0.5 2.5 7.4 0.2 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family TsaE PF02367.17 KXH26377.1 - 0.073 13.1 0.1 1.2 9.1 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF2075 PF09848.9 KXH26377.1 - 0.095 11.9 1.1 4.3 6.5 0.1 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Dynamin_N PF00350.23 KXH26377.1 - 0.11 12.5 0.2 7.5 6.6 0.0 2.4 2 0 0 2 2 2 0 Dynamin family IstB_IS21 PF01695.17 KXH26377.1 - 0.11 12.2 0.2 3.7 7.2 0.0 3.0 3 0 0 3 3 3 0 IstB-like ATP binding protein Pox_A32 PF04665.12 KXH26377.1 - 0.17 11.3 0.0 23 4.3 0.0 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_18 PF13238.6 KXH26377.1 - 0.2 12.2 0.0 40 4.8 0.0 2.8 2 0 0 2 2 2 0 AAA domain p450 PF00067.22 KXH26378.1 - 1.6e-52 178.8 0.0 2.1e-52 178.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans_2 PF11951.8 KXH26379.1 - 7e-05 21.8 0.2 9.6e-05 21.4 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pyr_redox_2 PF07992.14 KXH26380.1 - 8.4e-45 153.2 0.3 1.6e-44 152.3 0.3 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NIR_SIR PF01077.22 KXH26380.1 - 1.1e-17 64.0 0.0 2.1e-17 63.1 0.0 1.4 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Pyr_redox PF00070.27 KXH26380.1 - 6.7e-17 61.8 4.2 3e-16 59.8 0.3 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Fer2_BFD PF04324.15 KXH26380.1 - 1.5e-15 57.3 6.2 3.6e-11 43.2 6.1 2.8 2 0 0 2 2 2 2 BFD-like [2Fe-2S] binding domain Rieske_2 PF13806.6 KXH26380.1 - 9.9e-14 51.1 0.0 2.4e-06 27.4 0.0 2.8 2 0 0 2 2 2 2 Rieske-like [2Fe-2S] domain Rieske PF00355.26 KXH26380.1 - 2.3e-11 43.4 0.5 8.2e-06 25.7 0.0 3.0 3 0 0 3 3 3 2 Rieske [2Fe-2S] domain NIR_SIR_ferr PF03460.17 KXH26380.1 - 4.6e-08 32.8 0.0 9.9e-08 31.7 0.0 1.6 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain Rubredoxin_C PF18267.1 KXH26380.1 - 6.1e-06 26.1 0.1 0.096 12.6 0.0 3.7 4 0 0 4 4 4 2 Rubredoxin NAD+ reductase C-terminal domain Amino_oxidase PF01593.24 KXH26380.1 - 0.0018 17.6 0.7 1.2 8.3 0.0 2.3 1 1 1 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 KXH26380.1 - 0.0025 17.2 0.0 0.0053 16.1 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXH26380.1 - 0.0059 16.6 0.5 4.3 7.3 0.0 3.4 3 1 1 4 4 4 1 FAD-NAD(P)-binding GIDA PF01134.22 KXH26380.1 - 0.16 11.0 1.2 33 3.4 0.1 3.0 2 1 0 3 3 3 0 Glucose inhibited division protein A Methyltransf_11 PF08241.12 KXH26381.1 - 2e-17 63.6 0.0 3.3e-17 62.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXH26381.1 - 3.6e-17 62.7 0.0 5.5e-17 62.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH26381.1 - 5.2e-14 52.7 0.0 8.6e-14 52.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH26381.1 - 7.6e-11 42.6 0.0 1.2e-10 42.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH26381.1 - 9.1e-10 38.5 0.0 1.3e-09 38.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KXH26381.1 - 0.00024 20.6 0.0 0.00032 20.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KXH26381.1 - 0.016 14.7 0.0 0.026 14.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain CMAS PF02353.20 KXH26381.1 - 0.041 13.2 0.0 0.14 11.4 0.0 1.7 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_2 PF00891.18 KXH26381.1 - 0.12 11.7 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain SR-25 PF10500.9 KXH26381.1 - 2.4 7.7 7.4 3.4 7.2 7.4 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Herpes_pp85 PF04637.12 KXH26381.1 - 7.6 4.8 5.3 10 4.4 5.3 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) DHBP_synthase PF00926.19 KXH26382.1 - 1.7e-81 272.3 0.0 2e-81 272.1 0.0 1.0 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase DAO PF01266.24 KXH26383.1 - 2.4e-34 119.5 0.0 2.4e-34 119.5 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXH26383.1 - 0.0064 15.8 0.0 2.5 7.2 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXH26383.1 - 0.023 14.9 0.0 0.082 13.2 0.0 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain IFT57 PF10498.9 KXH26383.1 - 0.054 12.5 2.5 0.077 12.0 2.5 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 DNA_pol_phi PF04931.13 KXH26383.1 - 0.095 10.8 28.7 0.13 10.4 28.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF2457 PF10446.9 KXH26383.1 - 1.1 8.3 37.1 1.9 7.6 37.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) TFB6 PF17110.5 KXH26383.1 - 2.8 7.7 9.5 5.3 6.7 9.5 1.4 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH CDC45 PF02724.14 KXH26383.1 - 4.5 5.4 19.2 6.8 4.8 19.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 KXH26383.1 - 4.6 5.3 19.8 6.5 4.8 19.8 1.1 1 0 0 1 1 1 0 Nop14-like family Tom22 PF04281.13 KXH26383.1 - 7.6 6.3 11.0 15 5.4 11.0 1.4 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 Scaffolding_pro PF11418.8 KXH26385.1 - 0.041 14.4 0.0 0.099 13.2 0.0 1.6 1 0 0 1 1 1 0 Phi29 scaffolding protein DUF3682 PF12446.8 KXH26385.1 - 0.059 13.9 4.0 0.085 13.3 4.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) GRAS PF03514.14 KXH26385.1 - 0.074 12.0 0.4 0.13 11.2 0.4 1.4 1 1 0 1 1 1 0 GRAS domain family Nucleo_P87 PF07267.11 KXH26385.1 - 0.11 11.4 1.6 0.12 11.2 1.6 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Auts2 PF15336.6 KXH26385.1 - 0.13 12.4 4.5 0.1 12.7 3.5 1.4 1 1 0 1 1 1 0 Autism susceptibility gene 2 protein DUF1722 PF08349.11 KXH26385.1 - 0.14 12.5 0.1 0.25 11.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1722) Fungal_trans_2 PF11951.8 KXH26387.1 - 1.9e-26 92.8 0.5 2.9e-26 92.2 0.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain TFIIB PF00382.19 KXH26387.1 - 0.086 12.9 0.0 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 Transcription factor TFIIB repeat Methyltransf_33 PF10017.9 KXH26388.1 - 8.1e-78 261.7 0.0 1.1e-77 261.3 0.0 1.1 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent zf-C2H2 PF00096.26 KXH26390.1 - 4.4e-22 77.2 25.6 2e-05 24.7 0.2 4.7 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KXH26390.1 - 3.1e-17 62.1 27.9 2e-06 28.0 1.2 5.6 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 KXH26390.1 - 1.1e-11 44.5 22.9 0.0048 17.6 1.3 4.6 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KXH26390.1 - 5.5e-06 26.5 0.1 5.4 7.4 0.0 4.3 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 KXH26390.1 - 0.0015 18.2 8.1 0.023 14.5 0.8 3.3 3 0 0 3 3 3 2 zinc-finger C2H2-type zf-met PF12874.7 KXH26390.1 - 0.0018 18.6 7.9 3.2 8.3 0.0 4.0 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf_UBZ PF18439.1 KXH26390.1 - 0.0042 16.6 2.0 1.3 8.7 0.2 3.1 3 0 0 3 3 3 2 Ubiquitin-Binding Zinc Finger zf-C2HC_2 PF13913.6 KXH26390.1 - 0.16 11.9 6.6 5.1 7.1 0.2 3.6 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-MYST PF17772.1 KXH26390.1 - 0.26 10.9 2.0 4.8 6.9 0.0 3.0 3 0 0 3 3 3 0 MYST family zinc finger domain zf-ribbon_3 PF13248.6 KXH26390.1 - 0.27 10.7 1.8 23 4.6 0.1 3.3 3 0 0 3 3 3 0 zinc-ribbon domain FOXP-CC PF16159.5 KXH26390.1 - 0.33 11.6 2.7 23 5.7 0.4 2.9 2 1 1 3 3 3 0 FOXP coiled-coil domain Zn-ribbon_8 PF09723.10 KXH26390.1 - 0.59 10.3 8.7 2.8 8.2 0.8 3.2 1 1 3 4 4 4 0 Zinc ribbon domain zf-C2H2_aberr PF17017.5 KXH26390.1 - 0.66 10.1 1.5 3.9 7.6 0.1 2.1 2 0 0 2 2 2 0 Aberrant zinc-finger zf-TRAF PF02176.18 KXH26390.1 - 2.9 8.7 8.9 8.4 7.2 0.8 2.4 1 1 1 2 2 2 0 TRAF-type zinc finger XPA_N PF01286.18 KXH26390.1 - 3.7 7.7 7.3 0.97 9.5 0.5 3.0 4 0 0 4 4 4 0 XPA protein N-terminal DZR PF12773.7 KXH26390.1 - 4.3 7.4 8.4 1.7e+02 2.3 8.4 2.4 1 1 0 1 1 1 0 Double zinc ribbon DUF2256 PF10013.9 KXH26390.1 - 5.9 7.1 9.0 26 5.1 0.0 3.6 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2256) Ogr_Delta PF04606.12 KXH26390.1 - 7.1 6.7 8.5 16 5.6 0.3 2.4 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger DSBA PF01323.20 KXH26391.1 - 1.8e-34 119.2 0.0 2e-34 119.1 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 KXH26391.1 - 2.8e-06 27.6 0.0 4.3e-05 23.7 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_5 PF13743.6 KXH26391.1 - 0.02 14.5 0.0 0.044 13.5 0.0 1.5 2 0 0 2 2 2 0 Thioredoxin TFA2_Winged_2 PF18121.1 KXH26392.1 - 2.1e-19 69.0 0.5 4.6e-19 67.9 0.5 1.6 1 0 0 1 1 1 1 TFA2 Winged helix domain 2 TFIIE_beta PF02186.15 KXH26392.1 - 3.5e-12 46.4 0.0 8.4e-12 45.2 0.0 1.7 1 0 0 1 1 1 1 TFIIE beta subunit core domain DUF3123 PF11321.8 KXH26392.1 - 0.89 10.2 5.9 2.5 8.8 2.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3123) Cyt-b5 PF00173.28 KXH26393.1 - 2.1e-23 82.3 0.3 2.8e-23 81.9 0.3 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF2201 PF09967.9 KXH26393.1 - 0.036 14.2 0.0 0.047 13.8 0.0 1.1 1 0 0 1 1 1 0 VWA-like domain (DUF2201) F-actin_cap_A PF01267.17 KXH26394.1 - 4.5e-99 331.2 0.0 5.9e-99 330.8 0.0 1.1 1 0 0 1 1 1 1 F-actin capping protein alpha subunit Transket_pyr PF02779.24 KXH26394.1 - 1.3e-42 145.5 0.0 2.2e-42 144.7 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KXH26394.1 - 8e-33 113.0 0.0 1.8e-32 111.8 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain PFOR_II PF17147.4 KXH26394.1 - 0.0025 18.1 0.0 0.0064 16.8 0.0 1.7 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II ACAS_N PF16177.5 KXH26394.1 - 0.04 13.8 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 Acetyl-coenzyme A synthetase N-terminus CSTF2_hinge PF14327.6 KXH26394.1 - 0.07 13.6 0.0 0.23 11.9 0.0 1.9 1 0 0 1 1 1 0 Hinge domain of cleavage stimulation factor subunit 2 Cellulase PF00150.18 KXH26395.1 - 2.6e-09 36.9 1.7 2.6e-09 36.9 1.7 1.6 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Radical_SAM PF04055.21 KXH26395.1 - 0.011 16.1 0.7 0.046 14.1 0.0 2.2 2 1 1 3 3 3 0 Radical SAM superfamily Adipogenin PF15202.6 KXH26395.1 - 0.019 14.9 0.1 0.04 13.9 0.1 1.5 1 0 0 1 1 1 0 Adipogenin EphA2_TM PF14575.6 KXH26395.1 - 0.033 15.1 4.1 0.046 14.6 0.0 2.6 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF4064 PF13273.6 KXH26395.1 - 0.13 12.6 0.0 0.28 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) LAP1C PF05609.12 KXH26395.1 - 0.44 9.6 4.3 0.78 8.8 4.3 1.3 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) SNARE PF05739.19 KXH26395.1 - 7.3 6.7 6.1 18 5.4 6.1 1.6 1 0 0 1 1 1 0 SNARE domain PsaX PF08078.12 KXH26395.1 - 8.5 6.4 6.6 8.2 6.5 0.0 2.3 2 0 0 2 2 2 0 PsaX family MFS_1 PF07690.16 KXH26396.1 - 1e-37 129.9 39.2 1e-37 129.9 39.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH26396.1 - 8.2e-14 51.3 7.9 8.2e-14 51.3 7.9 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KXH26396.1 - 4.2e-08 32.1 3.5 4.2e-08 32.1 3.5 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) PAS PF00989.25 KXH26397.1 - 5.5e-05 23.1 0.0 0.00013 22.0 0.0 1.6 1 0 0 1 1 1 1 PAS fold Zn_clus PF00172.18 KXH26397.1 - 0.0034 17.5 8.8 0.0078 16.3 8.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Flavokinase PF01687.17 KXH26398.1 - 3.1e-37 127.3 0.0 4.4e-37 126.8 0.0 1.2 1 0 0 1 1 1 1 Riboflavin kinase Epimerase PF01370.21 KXH26399.1 - 4.7e-08 32.8 0.0 6.2e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KXH26399.1 - 6.9e-08 32.6 0.3 8.7e-08 32.3 0.3 1.3 1 0 0 1 1 1 1 NAD(P)H-binding HIM1 PF08732.10 KXH26399.1 - 2.3e-07 30.5 0.0 3.3e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 HIM1 NmrA PF05368.13 KXH26399.1 - 0.00045 19.8 0.7 0.0018 17.9 0.7 1.8 1 1 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.24 KXH26399.1 - 0.051 14.0 0.1 0.12 12.8 0.0 1.6 1 1 1 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Myb_DNA-binding PF00249.31 KXH26422.1 - 2.2e-23 82.2 1.0 2.7e-13 49.9 0.0 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KXH26422.1 - 3.8e-16 59.1 1.5 4.1e-13 49.4 0.0 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain DUF2774 PF11242.8 KXH26422.1 - 0.017 15.3 0.0 0.14 12.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2774) HTH_23 PF13384.6 KXH26422.1 - 0.14 12.0 0.4 0.58 10.0 0.2 2.0 2 0 0 2 2 2 0 Homeodomain-like domain zf-C2H2 PF00096.26 KXH26426.1 - 1.4e-10 41.0 20.5 3.2e-06 27.3 2.3 3.3 3 0 0 3 3 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KXH26426.1 - 1.9e-08 34.4 14.3 1.4e-07 31.6 6.1 3.4 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KXH26426.1 - 3.2e-07 30.6 15.5 0.00098 19.8 1.3 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KXH26426.1 - 2.9e-06 27.4 5.1 0.0014 18.8 0.7 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KXH26426.1 - 3.2e-06 27.3 6.0 0.00011 22.5 0.3 2.8 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KXH26426.1 - 0.0025 17.8 11.3 0.025 14.6 2.9 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 KXH26426.1 - 0.0032 17.1 4.7 0.13 11.9 0.2 2.5 1 1 1 2 2 2 2 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_3rep PF18868.1 KXH26426.1 - 0.11 13.1 3.3 1.2 9.8 0.3 2.6 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats Raftlin PF15250.6 KXH26426.1 - 0.19 10.4 1.6 0.26 10.0 1.6 1.1 1 0 0 1 1 1 0 Raftlin zf_UBZ PF18439.1 KXH26426.1 - 0.22 11.2 3.4 5.7 6.6 0.4 2.9 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-C2H2_2 PF12756.7 KXH26426.1 - 1 9.8 5.0 16 5.9 0.4 2.4 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-BED PF02892.15 KXH26426.1 - 1.1 9.3 7.7 0.67 10.0 3.4 2.4 1 1 1 2 2 2 0 BED zinc finger Zn-ribbon_8 PF09723.10 KXH26426.1 - 1.5 9.0 5.9 7.5 6.8 0.9 2.9 1 1 1 2 2 2 0 Zinc ribbon domain zf-C2H2_11 PF16622.5 KXH26426.1 - 5.6 6.8 13.1 1.5 8.6 0.2 3.1 3 0 0 3 3 3 0 zinc-finger C2H2-type DUF629 PF04780.12 KXH26426.1 - 8.9 4.7 6.3 15 4.0 0.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF629) RAP1 PF07218.11 KXH26426.1 - 9.1 4.4 8.6 2.8 6.1 4.2 2.0 2 0 0 2 2 2 0 Rhoptry-associated protein 1 (RAP-1) zf-C2HE PF16278.5 KXH26426.1 - 9.4 6.8 7.7 1.7e+02 2.8 7.7 2.5 1 1 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger DUF2220 PF09983.9 KXH26428.1 - 0.028 13.8 0.1 0.029 13.7 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria C-term(DUF2220) AMP-binding PF00501.28 KXH26464.1 - 3.5e-72 243.3 0.1 7.1e-36 123.7 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 KXH26464.1 - 2.5e-11 44.4 0.2 5.4e-11 43.3 0.2 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Collagen PF01391.18 KXH26464.1 - 0.077 12.8 0.6 0.16 11.7 0.6 1.4 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) DUF3082 PF11282.8 KXH26464.1 - 0.33 11.2 2.7 0.76 10.1 2.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3082) IF4E PF01652.18 KXH26465.1 - 4.1e-54 182.7 0.1 5.3e-54 182.3 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E XRN1_DBM PF18245.1 KXH26466.1 - 0.81 9.7 3.0 7.5 6.7 0.1 2.8 2 0 0 2 2 2 0 5-3 exonuclease XRN1 DCP1-binding motif HSP70 PF00012.20 KXH26467.1 - 2.3e-219 729.6 7.5 2.6e-219 729.4 7.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KXH26467.1 - 4.8e-16 58.5 0.2 4.3e-15 55.3 0.1 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 KXH26467.1 - 0.0038 17.0 0.0 0.0078 16.0 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.10 KXH26467.1 - 0.017 14.1 0.9 0.054 12.5 0.3 2.1 2 1 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain Tyr-DNA_phospho PF06087.12 KXH26497.1 - 6.2e-84 282.3 0.0 8.2e-84 282.0 0.0 1.1 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase UIM PF02809.20 KXH26497.1 - 0.00085 19.1 0.6 0.0025 17.6 0.6 1.8 1 0 0 1 1 1 1 Ubiquitin interaction motif PLDc_2 PF13091.6 KXH26497.1 - 0.001 19.0 0.0 0.011 15.6 0.0 2.3 2 0 0 2 2 2 1 PLD-like domain FAM110_C PF14160.6 KXH26497.1 - 0.21 12.7 0.0 0.21 12.7 0.0 2.7 3 0 0 3 3 3 0 Centrosome-associated C terminus PNRC PF15365.6 KXH26498.1 - 3e-08 33.2 8.4 3e-08 33.2 8.4 3.8 4 0 0 4 4 4 1 Proline-rich nuclear receptor coactivator motif zf-rbx1 PF12678.7 KXH26499.1 - 6.9e-25 87.1 12.9 9.7e-25 86.6 12.9 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KXH26499.1 - 4.6e-17 61.8 9.8 6.1e-17 61.5 9.8 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 KXH26499.1 - 3.8e-06 27.1 14.1 0.00014 22.1 14.1 2.2 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KXH26499.1 - 5.2e-05 23.0 3.1 5.2e-05 23.0 3.1 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXH26499.1 - 0.0016 18.3 11.5 0.028 14.3 11.5 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KXH26499.1 - 0.19 11.6 10.7 0.6 10.0 4.5 2.6 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KXH26499.1 - 0.34 10.7 15.9 29 4.5 15.9 2.4 1 1 0 1 1 1 0 RING-like zinc finger zf-RING_UBOX PF13445.6 KXH26499.1 - 0.4 10.7 6.8 1.5 9.0 6.8 2.0 1 1 0 1 1 1 0 RING-type zinc-finger FANCL_C PF11793.8 KXH26499.1 - 1 9.6 9.4 5.9 7.2 9.6 2.0 1 1 1 2 2 2 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 KXH26499.1 - 1.3 8.7 15.0 0.32 10.6 4.9 2.3 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 KXH26499.1 - 6.3 6.9 12.2 55 3.8 12.2 2.5 1 1 0 1 1 1 0 zinc-RING finger domain SPC12 PF06645.13 KXH26500.1 - 3.7e-31 107.0 0.2 4.4e-31 106.8 0.2 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) DUF3040 PF11239.8 KXH26500.1 - 0.081 13.2 0.6 0.11 12.8 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) CorA PF01544.18 KXH26501.1 - 6e-42 143.9 0.0 8.3e-42 143.5 0.0 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein zf-Tim10_DDP PF02953.15 KXH26502.1 - 4.5e-23 80.7 0.8 5.6e-23 80.4 0.8 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Ribosomal_L23eN PF03939.13 KXH26503.1 - 1.2e-24 86.2 6.0 1.2e-24 86.2 6.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 KXH26503.1 - 1.4e-15 57.4 0.6 2.5e-15 56.6 0.6 1.5 1 0 0 1 1 1 1 Ribosomal protein L23 Bmt2 PF11968.8 KXH26504.1 - 7.1e-84 281.1 0.0 9.2e-84 280.7 0.0 1.1 1 0 0 1 1 1 1 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 Methyltransf_23 PF13489.6 KXH26504.1 - 0.011 15.6 0.0 0.015 15.1 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain HAD_2 PF13419.6 KXH26505.1 - 0.00075 19.6 0.0 0.0011 19.1 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KXH26505.1 - 0.0062 16.8 0.0 0.0079 16.5 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Pkinase PF00069.25 KXH26506.1 - 9e-57 192.4 0.0 2.4e-56 191.0 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXH26506.1 - 2.2e-34 118.9 0.0 3.5e-34 118.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXH26506.1 - 6.9e-13 48.6 0.0 1.6e-10 40.8 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 KXH26506.1 - 0.025 14.0 0.0 0.045 13.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KXH26506.1 - 0.042 12.6 0.1 0.32 9.7 0.0 2.0 2 0 0 2 2 2 0 Fungal protein kinase APH PF01636.23 KXH26506.1 - 0.071 13.0 0.1 0.33 10.8 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family Aa_trans PF01490.18 KXH26507.1 - 1e-58 199.0 32.6 1.3e-58 198.7 32.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein NICE-1 PF15845.5 KXH26508.1 - 0.19 12.5 0.2 0.19 12.5 0.2 2.3 2 0 0 2 2 2 0 Cysteine-rich C-terminal 1 family DUF2448 PF10476.9 KXH26508.1 - 2.5 7.9 6.5 0.44 10.4 0.1 2.7 3 1 0 3 3 3 0 Protein of unknown function C-terminus (DUF2448) DUF3138 PF11336.8 KXH26508.1 - 5.9 5.4 8.0 0.21 10.2 0.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3138) WD40 PF00400.32 KXH26509.1 - 1.4e-59 196.6 14.5 7.2e-09 36.1 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXH26509.1 - 1.5e-15 57.3 0.0 0.0027 18.0 0.0 5.3 2 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KXH26509.1 - 6.3e-08 31.9 0.2 0.13 11.2 0.0 5.2 2 2 3 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KXH26509.1 - 1.2e-05 24.8 0.0 0.26 10.6 0.0 4.5 4 1 1 5 5 5 2 WD40-like domain Nup160 PF11715.8 KXH26509.1 - 0.0063 15.2 0.2 1.2 7.6 0.0 3.5 1 1 3 4 4 4 1 Nucleoporin Nup120/160 PD40 PF07676.12 KXH26509.1 - 0.0088 16.0 0.0 7.3 6.7 0.0 4.3 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 KXH26509.1 - 0.016 13.7 0.4 0.23 9.9 0.2 2.5 1 1 1 2 2 2 0 Cytochrome D1 heme domain Nbas_N PF15492.6 KXH26509.1 - 0.019 14.3 0.1 13 5.0 0.0 3.1 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Nucleoporin_N PF08801.11 KXH26509.1 - 0.031 13.0 0.1 3.4 6.3 0.1 3.3 2 1 1 3 3 3 0 Nup133 N terminal like Mcl1_mid PF12341.8 KXH26509.1 - 0.17 11.2 0.1 0.5 9.7 0.0 1.7 2 0 0 2 2 2 0 Minichromosome loss protein, Mcl1, middle region MoeA_C PF03454.15 KXH26520.1 - 0.14 12.4 0.4 0.16 12.2 0.4 1.1 1 0 0 1 1 1 0 MoeA C-terminal region (domain IV) Ank_2 PF12796.7 KXH26522.1 - 4.4e-29 100.9 1.4 1.1e-08 35.5 0.0 4.8 2 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXH26522.1 - 5.6e-28 96.9 2.9 4.3e-07 30.4 0.1 6.8 4 2 4 8 8 8 5 Ankyrin repeats (many copies) SPX PF03105.19 KXH26522.1 - 1.9e-19 70.9 18.2 1.7e-09 38.1 1.4 3.2 1 1 2 3 3 3 3 SPX domain Ank_3 PF13606.6 KXH26522.1 - 2.6e-17 61.1 6.9 0.006 17.0 0.0 7.8 9 0 0 9 9 9 4 Ankyrin repeat Ank_5 PF13857.6 KXH26522.1 - 3.7e-17 62.2 6.9 0.00065 19.9 0.0 6.5 2 2 5 7 7 7 7 Ankyrin repeats (many copies) Ank PF00023.30 KXH26522.1 - 1.5e-11 44.2 8.9 0.016 15.6 0.0 7.6 8 0 0 8 8 8 3 Ankyrin repeat GDPD PF03009.17 KXH26522.1 - 5.8e-08 32.8 0.0 2.9e-07 30.5 0.0 2.1 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family RVP PF00077.20 KXH26522.1 - 0.023 15.0 0.0 0.1 12.9 0.0 2.0 2 0 0 2 2 2 0 Retroviral aspartyl protease CUE PF02845.16 KXH26523.1 - 7.5e-12 44.7 0.0 1.3e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 CUE domain HA2 PF04408.23 KXH26524.1 - 5.1e-17 62.1 1.7 8.7e-17 61.4 0.1 2.2 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KXH26524.1 - 3.3e-14 53.0 0.0 7.9e-14 51.8 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KXH26524.1 - 3.1e-13 50.0 0.0 7.9e-13 48.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 KXH26524.1 - 2.3e-05 24.7 0.1 8.6e-05 22.8 0.1 2.0 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 KXH26524.1 - 8.7e-05 23.1 0.9 0.0094 16.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KXH26524.1 - 0.00016 21.5 0.1 0.00016 21.5 0.1 2.0 2 0 0 2 2 2 1 AAA domain DEAD PF00270.29 KXH26524.1 - 0.001 18.9 1.2 0.0032 17.3 1.2 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 KXH26524.1 - 0.0012 19.2 0.2 0.0029 18.0 0.2 1.6 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 KXH26524.1 - 0.018 14.1 0.0 0.04 13.0 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_14 PF13173.6 KXH26524.1 - 0.042 13.9 0.5 3.2 7.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KXH26524.1 - 0.054 13.0 0.3 0.25 10.8 0.0 2.2 3 0 0 3 3 3 0 P-loop containing dynein motor region Zeta_toxin PF06414.12 KXH26524.1 - 0.071 12.4 0.2 0.23 10.7 0.1 1.8 1 1 0 1 1 1 0 Zeta toxin PhoH PF02562.16 KXH26524.1 - 0.085 12.3 0.2 0.65 9.4 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein cobW PF02492.19 KXH26524.1 - 0.12 12.0 0.2 1.7 8.2 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.6 KXH26524.1 - 0.15 11.8 0.0 0.42 10.4 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain SKG6 PF08693.10 KXH26527.1 - 5e-13 48.2 1.8 1.1e-12 47.2 1.8 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain CD34_antigen PF06365.12 KXH26527.1 - 0.022 14.3 0.1 0.063 12.9 0.0 1.7 2 0 0 2 2 2 0 CD34/Podocalyxin family TFIIA PF03153.13 KXH26527.1 - 0.023 14.7 11.2 0.037 14.0 11.2 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CcmD PF04995.14 KXH26527.1 - 0.038 14.1 0.3 0.065 13.3 0.3 1.3 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) DUF4131 PF13567.6 KXH26527.1 - 0.17 11.6 1.3 8.6 6.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Endomucin PF07010.12 KXH26527.1 - 0.4 10.6 28.5 0.75 9.7 28.5 1.5 1 0 0 1 1 1 0 Endomucin Suf PF05843.14 KXH26527.1 - 1.7 8.5 8.3 2.7 7.9 8.3 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Ndc1_Nup PF09531.10 KXH26527.1 - 3.2 6.3 9.0 4.1 6.0 9.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup COesterase PF00135.28 KXH26528.1 - 1.6e-59 202.1 0.0 4.1e-54 184.3 0.0 2.1 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 KXH26528.1 - 0.00011 22.1 0.3 0.00054 19.9 0.3 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Prok_Ub PF14454.6 KXH26528.1 - 0.19 11.4 0.0 0.44 10.2 0.0 1.5 1 0 0 1 1 1 0 Prokaryotic Ubiquitin MSP1a PF11670.8 KXH26529.1 - 5.2 6.3 10.1 1.2 8.3 1.2 2.6 2 0 0 2 2 2 0 Major surface protein 1a (MSP1a) DASH_Dad2 PF08654.10 KXH26530.1 - 3.7e-32 110.7 0.8 3.7e-32 110.7 0.8 1.4 2 0 0 2 2 2 1 DASH complex subunit Dad2 Rogdi_lz PF10259.9 KXH26530.1 - 0.005 16.3 0.5 0.0054 16.2 0.5 1.1 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein Seryl_tRNA_N PF02403.22 KXH26530.1 - 0.019 15.2 0.2 0.039 14.2 0.2 1.5 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DASH_Duo1 PF08651.10 KXH26530.1 - 0.085 12.6 0.2 0.15 11.9 0.2 1.3 1 0 0 1 1 1 0 DASH complex subunit Duo1 Shugoshin_C PF07557.11 KXH26531.1 - 2.6e-12 46.3 7.3 2e-11 43.5 7.3 2.7 1 0 0 1 1 1 1 Shugoshin C terminus Shugoshin_N PF07558.11 KXH26531.1 - 0.00014 21.7 2.7 0.00034 20.4 2.7 1.7 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region Mod_r PF07200.13 KXH26531.1 - 0.49 10.5 3.9 0.18 11.9 0.6 1.9 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Metallophos_2 PF12850.7 KXH26532.1 - 6e-12 46.1 0.0 7.8e-12 45.7 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Aminotran_5 PF00266.19 KXH26533.1 - 1.3e-26 93.4 0.0 1.8e-26 93.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V B12-binding PF02310.19 KXH26533.1 - 0.0016 18.5 0.1 0.055 13.5 0.0 2.6 2 1 1 3 3 3 1 B12 binding domain RusA PF05866.11 KXH26533.1 - 0.12 12.9 0.0 0.3 11.7 0.0 1.6 1 0 0 1 1 1 0 Endodeoxyribonuclease RusA CRM1_C PF08767.11 KXH26534.1 - 4.7e-135 449.9 4.2 4.7e-135 449.9 4.2 2.9 2 1 0 2 2 2 1 CRM1 C terminal Xpo1 PF08389.12 KXH26534.1 - 5.4e-41 140.1 13.9 8.1e-41 139.5 6.3 4.2 3 1 1 4 4 4 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 KXH26534.1 - 1.1e-33 114.7 4.0 3.4e-33 113.1 4.0 2.0 1 0 0 1 1 1 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 KXH26534.1 - 9.9e-28 96.0 1.2 9.9e-28 96.0 1.2 3.3 4 0 0 4 4 4 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 KXH26534.1 - 5.7e-18 64.1 1.1 1.6e-17 62.7 1.1 1.8 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 KXH26534.1 - 7.7e-13 48.2 0.1 2.6e-12 46.5 0.1 2.0 1 0 0 1 1 1 1 Importin-beta N-terminal domain MMS19_C PF12460.8 KXH26534.1 - 0.0068 15.6 1.6 0.0068 15.6 1.6 3.9 3 2 1 4 4 4 1 RNAPII transcription regulator C-terminal Vac14_Fab1_bd PF12755.7 KXH26534.1 - 0.069 13.8 5.2 3.6 8.3 0.0 5.3 6 0 0 6 6 5 0 Vacuolar 14 Fab1-binding region HD_assoc PF13286.6 KXH26534.1 - 0.076 13.6 0.7 31 5.2 0.2 3.9 4 0 0 4 4 3 0 Phosphohydrolase-associated domain DUF3385 PF11865.8 KXH26534.1 - 0.24 11.3 9.7 0.33 10.9 0.0 4.4 5 1 0 5 5 5 0 Domain of unknown function (DUF3385) FliH PF02108.16 KXH26534.1 - 0.89 9.6 3.7 1.9 8.5 0.0 3.0 3 0 0 3 3 3 0 Flagellar assembly protein FliH AAA PF00004.29 KXH26535.1 - 1.3e-64 216.6 0.0 2.7e-45 154.0 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KXH26535.1 - 4.7e-12 45.5 1.2 5.9e-05 22.8 0.1 2.7 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 KXH26535.1 - 7e-10 39.6 1.6 0.00047 20.6 0.0 4.7 3 2 0 3 3 3 2 AAA ATPase domain AAA_5 PF07728.14 KXH26535.1 - 5e-08 33.0 0.0 0.0034 17.4 0.0 3.0 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KXH26535.1 - 2.3e-07 31.1 0.1 0.018 15.3 0.0 5.1 3 2 2 5 5 4 1 AAA domain AAA_18 PF13238.6 KXH26535.1 - 4.5e-07 30.5 0.0 0.014 15.9 0.0 3.0 2 1 0 2 2 2 2 AAA domain RuvB_N PF05496.12 KXH26535.1 - 2.3e-06 27.5 0.0 0.00037 20.3 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 KXH26535.1 - 1.7e-05 25.0 0.0 0.0046 17.1 0.0 2.8 2 1 0 2 2 2 1 AAA domain Rad17 PF03215.15 KXH26535.1 - 5.4e-05 23.2 0.0 0.085 12.8 0.0 2.6 2 1 0 2 2 2 2 Rad17 P-loop domain Zeta_toxin PF06414.12 KXH26535.1 - 7.6e-05 22.1 0.0 0.038 13.3 0.0 3.1 3 0 0 3 3 3 1 Zeta toxin AAA_28 PF13521.6 KXH26535.1 - 8e-05 22.9 0.6 0.73 10.1 0.0 3.2 3 1 0 3 3 2 2 AAA domain IstB_IS21 PF01695.17 KXH26535.1 - 0.00016 21.5 0.0 0.031 14.0 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_17 PF13207.6 KXH26535.1 - 0.00017 22.0 0.0 0.91 9.9 0.0 3.1 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.14 KXH26535.1 - 0.00018 21.7 0.0 0.0017 18.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.22 KXH26535.1 - 0.00042 20.7 0.0 0.054 13.9 0.0 2.6 2 0 0 2 2 2 1 RNA helicase Mg_chelatase PF01078.21 KXH26535.1 - 0.00059 19.3 0.1 0.11 11.9 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 KXH26535.1 - 0.00088 18.8 0.0 0.76 9.3 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region Sigma54_activ_2 PF14532.6 KXH26535.1 - 0.00089 19.4 0.0 0.13 12.3 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain Sigma54_activat PF00158.26 KXH26535.1 - 0.001 18.8 0.0 0.71 9.6 0.0 2.7 2 0 0 2 2 2 1 Sigma-54 interaction domain DUF815 PF05673.13 KXH26535.1 - 0.0012 18.0 0.0 0.68 9.0 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_11 PF13086.6 KXH26535.1 - 0.0031 17.3 3.5 1.5 8.6 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_14 PF13173.6 KXH26535.1 - 0.0037 17.3 0.0 0.06 13.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 KXH26535.1 - 0.006 15.8 0.0 0.28 10.3 0.0 2.3 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_25 PF13481.6 KXH26535.1 - 0.0091 15.6 0.2 5.5 6.5 0.0 3.9 3 1 1 4 4 4 0 AAA domain AAA_24 PF13479.6 KXH26535.1 - 0.024 14.4 0.0 3.5 7.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KXH26535.1 - 0.027 15.0 0.0 2.7 8.5 0.0 2.9 2 0 0 2 2 2 0 ABC transporter TniB PF05621.11 KXH26535.1 - 0.034 13.5 0.0 0.78 9.1 0.0 2.9 4 0 0 4 4 3 0 Bacterial TniB protein NACHT PF05729.12 KXH26535.1 - 0.043 13.7 0.1 5.3 6.9 0.0 3.0 4 0 0 4 4 3 0 NACHT domain TsaE PF02367.17 KXH26535.1 - 0.059 13.4 0.0 1.8 8.6 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_3 PF07726.11 KXH26535.1 - 0.065 13.1 0.0 2.5 8.0 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 KXH26535.1 - 0.07 13.5 1.9 9.3 6.6 0.0 3.2 3 0 0 3 3 3 0 AAA domain Viral_helicase1 PF01443.18 KXH26535.1 - 0.084 12.6 0.0 1.4 8.6 0.0 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.22 KXH26535.1 - 0.14 11.3 0.0 1.1 8.4 0.0 2.4 3 0 0 3 3 3 0 NB-ARC domain IPT PF01745.16 KXH26535.1 - 0.48 9.8 1.3 16 4.8 0.0 2.8 3 0 0 3 3 3 0 Isopentenyl transferase Cytochrom_C PF00034.21 KXH26536.1 - 2.7e-12 47.7 0.1 3.7e-12 47.2 0.1 1.2 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 KXH26536.1 - 3.9e-09 36.7 2.3 1.5e-08 34.9 2.3 1.7 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 KXH26536.1 - 0.013 15.2 1.8 0.067 12.9 1.8 2.1 1 1 0 1 1 1 0 Cytochrome c-550 domain RNase_PH PF01138.21 KXH26538.1 - 3.4e-13 50.2 0.0 6.3e-13 49.4 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KXH26538.1 - 0.018 15.0 0.0 0.044 13.8 0.0 1.6 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 EST1_DNA_bind PF10373.9 KXH26702.1 - 5.8e-10 39.1 0.4 1.3e-09 37.9 0.4 1.6 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain HCO3_cotransp PF00955.21 KXH26705.1 - 1.4e-86 291.3 9.4 5.4e-46 157.5 4.6 2.0 1 1 1 2 2 2 2 HCO3- transporter family TNFR_16_TM PF18422.1 KXH26705.1 - 8.3 6.5 13.6 0.9 9.6 4.8 2.9 2 0 0 2 2 2 0 Tumor necrosis factor receptor member 16 trans-membrane domain Homeodomain PF00046.29 KXH26706.1 - 8.3e-18 64.0 3.0 1.5e-17 63.1 3.0 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KXH26706.1 - 0.005 16.7 0.1 0.011 15.6 0.1 1.6 1 0 0 1 1 1 1 Homeobox KN domain Cwf_Cwc_15 PF04889.12 KXH26706.1 - 0.7 9.6 12.2 1.2 8.8 12.2 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RR_TM4-6 PF06459.12 KXH26706.1 - 4.3 7.1 6.9 77 3.0 7.6 2.3 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 NUP50 PF08911.11 KXH26706.1 - 5.3 7.8 8.4 0.42 11.3 0.5 3.0 2 0 0 2 2 2 0 NUP50 (Nucleoporin 50 kDa) Aminotran_1_2 PF00155.21 KXH26744.1 - 3.9e-81 273.0 0.0 4.7e-81 272.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Sugar_tr PF00083.24 KXH26745.1 - 7.9e-82 275.5 20.6 9.1e-82 275.3 20.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH26745.1 - 3.5e-24 85.4 21.6 3.5e-24 85.4 21.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KXH26745.1 - 0.0017 16.9 1.0 0.0027 16.2 1.0 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Gate PF07670.14 KXH26745.1 - 0.74 10.1 9.7 43 4.4 0.1 3.6 1 1 1 2 2 2 0 Nucleoside recognition Ank_2 PF12796.7 KXH26746.1 - 1.2e-81 269.3 22.9 2.2e-12 47.4 0.0 11.7 3 2 13 16 16 16 14 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXH26746.1 - 2e-50 168.2 23.2 2.6e-07 30.8 0.1 14.2 8 4 7 15 15 14 8 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXH26746.1 - 1.6e-48 162.4 21.8 6.1e-06 26.7 0.0 14.8 8 4 6 14 14 14 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXH26746.1 - 1.7e-41 135.4 14.3 0.0013 19.0 0.0 18.5 18 0 0 18 18 17 8 Ankyrin repeat Ank PF00023.30 KXH26746.1 - 5.1e-33 112.1 31.3 0.00012 22.4 0.0 17.4 19 0 0 19 19 19 9 Ankyrin repeat NACHT PF05729.12 KXH26746.1 - 9.9e-09 35.3 0.4 4.8e-08 33.1 0.0 2.4 3 0 0 3 3 3 1 NACHT domain AAA_22 PF13401.6 KXH26746.1 - 5.4e-08 33.2 0.0 4.5e-07 30.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KXH26746.1 - 8.5e-05 23.0 0.0 0.00031 21.1 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 KXH26746.1 - 0.0072 16.3 0.1 0.015 15.2 0.1 1.5 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 KXH26746.1 - 0.043 14.2 0.0 0.15 12.4 0.0 2.0 1 0 0 1 1 1 0 RNA helicase Goodbye PF17109.5 KXH26746.1 - 0.098 13.1 1.1 0.29 11.6 0.0 2.5 2 0 0 2 2 1 0 fungal STAND N-terminal Goodbye domain p450 PF00067.22 KXH26747.1 - 1.5e-44 152.5 0.0 7e-33 114.1 0.0 2.5 2 1 0 2 2 2 2 Cytochrome P450 Lactonase PF10282.9 KXH26748.1 - 9.8e-22 77.7 5.8 5.9e-20 71.8 4.3 2.1 1 1 1 2 2 2 2 Lactonase, 7-bladed beta-propeller SGL PF08450.12 KXH26748.1 - 0.0023 17.6 0.5 0.0091 15.6 0.6 1.9 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region CorA PF01544.18 KXH26749.1 - 0.00026 20.4 0.4 0.00091 18.6 0.0 1.9 2 1 0 2 2 2 1 CorA-like Mg2+ transporter protein ADH_N PF08240.12 KXH26750.1 - 7.5e-14 51.5 0.2 2e-13 50.2 0.2 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXH26750.1 - 1.5e-05 24.9 0.2 7.7e-05 22.7 0.2 2.0 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KXH26750.1 - 0.0035 16.9 0.0 0.0055 16.2 0.0 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 KXH26750.1 - 0.0079 15.5 0.8 0.012 14.9 0.8 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 KXH26750.1 - 0.018 13.8 0.0 0.025 13.3 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein AA_permease_2 PF13520.6 KXH26751.1 - 1.1e-60 205.7 55.6 1.3e-60 205.4 55.6 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXH26751.1 - 3e-26 92.1 47.4 4e-26 91.6 47.4 1.1 1 0 0 1 1 1 1 Amino acid permease MatE PF01554.18 KXH26753.1 - 7.4e-54 181.8 32.1 4.1e-34 117.6 11.1 2.1 2 0 0 2 2 2 2 MatE Como_SCP PF02248.16 KXH26753.1 - 0.043 13.4 0.1 0.078 12.5 0.1 1.3 1 0 0 1 1 1 0 Small coat protein DUF5389 PF17364.2 KXH26753.1 - 0.098 12.7 0.1 0.098 12.7 0.1 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5389) Polysacc_synt_C PF14667.6 KXH26753.1 - 2.1 8.4 38.1 0.066 13.3 13.6 4.7 3 2 1 4 4 4 0 Polysaccharide biosynthesis C-terminal domain HET PF06985.11 KXH26754.1 - 3.3e-07 30.8 0.2 6.7e-07 29.8 0.2 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Dicty_REP PF05086.12 KXH26813.1 - 0.18 9.8 3.1 0.2 9.6 3.1 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Ion_trans_2 PF07885.16 KXH26817.1 - 2.7e-32 110.6 24.8 3.1e-19 68.7 2.1 3.2 3 1 0 3 3 3 2 Ion channel Ion_trans PF00520.31 KXH26817.1 - 5.9e-05 22.4 12.6 0.00098 18.4 0.7 2.7 3 0 0 3 3 3 2 Ion transport protein SieB PF14163.6 KXH26817.1 - 0.28 10.6 1.2 1.2 8.6 0.0 2.7 3 0 0 3 3 3 0 Super-infection exclusion protein B zf-RING_4 PF14570.6 KXH26818.1 - 8.4e-20 70.3 12.2 1.5e-19 69.5 12.2 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RRM_1 PF00076.22 KXH26818.1 - 2e-10 40.3 0.0 8e-10 38.4 0.0 2.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.6 KXH26818.1 - 1.1e-07 31.6 7.3 2.1e-07 30.7 7.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.12 KXH26818.1 - 0.00024 20.5 3.9 0.00024 20.5 3.9 2.7 3 0 0 3 3 3 1 Rtf2 RING-finger zf-RING_2 PF13639.6 KXH26818.1 - 0.0006 20.1 10.0 0.0006 20.1 10.0 1.7 2 0 0 2 2 1 1 Ring finger domain SET_assoc PF11767.8 KXH26818.1 - 0.0012 18.4 0.0 0.0025 17.4 0.0 1.4 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated Prok-RING_4 PF14447.6 KXH26818.1 - 0.003 17.4 9.1 0.17 11.8 9.8 2.4 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 FYVE PF01363.21 KXH26818.1 - 0.041 14.0 4.0 0.088 13.0 4.0 1.5 1 0 0 1 1 1 0 FYVE zinc finger Nup35_RRM_2 PF14605.6 KXH26818.1 - 0.054 13.5 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Baculo_IE-1 PF05290.11 KXH26818.1 - 0.084 12.8 5.2 0.15 12.1 5.2 1.3 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-C3HC4 PF00097.25 KXH26818.1 - 0.14 12.1 10.3 0.28 11.1 10.3 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXH26818.1 - 0.3 11.1 10.3 0.59 10.1 10.3 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-UDP PF14569.6 KXH26818.1 - 0.35 11.0 4.5 0.85 9.8 4.5 1.6 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-C3HC4_2 PF13923.6 KXH26818.1 - 1.8 8.4 9.9 3.6 7.5 9.9 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Complex1_30kDa PF00329.19 KXH26819.1 - 3.2e-45 153.7 0.0 4.2e-45 153.3 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit DUF2087 PF09860.9 KXH26819.1 - 0.095 12.9 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2087) ASCH PF04266.14 KXH26821.1 - 0.028 15.0 0.0 0.14 12.7 0.0 2.1 2 0 0 2 2 2 0 ASCH domain Mei5 PF10376.9 KXH26822.1 - 0.1 12.4 0.0 0.33 10.8 0.0 1.9 2 1 0 2 2 2 0 Double-strand recombination repair protein DUF4680 PF15730.5 KXH26822.1 - 2.4 8.5 5.3 5.6 7.3 5.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4680) SRF-TF PF00319.18 KXH26823.1 - 1.5e-22 78.8 0.3 2.2e-22 78.3 0.3 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Peptidase_S66 PF02016.15 KXH26865.1 - 3.7e-27 94.8 0.0 5.2e-27 94.3 0.0 1.2 1 0 0 1 1 1 1 LD-carboxypeptidase N-terminal domain SUFU_C PF12470.8 KXH26865.1 - 0.16 12.0 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 Suppressor of Fused Gli/Ci N terminal binding domain Glycos_transf_2 PF00535.26 KXH26867.1 - 1.8e-27 96.2 0.2 7.1e-27 94.3 0.1 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KXH26867.1 - 4.3e-25 88.9 0.0 9.1e-25 87.9 0.0 1.5 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 KXH26867.1 - 2.4e-11 43.9 1.5 4.6e-11 43.0 1.5 1.4 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 KXH26867.1 - 6.8e-10 38.7 0.0 1.5e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 21 Chitin_synth_2 PF03142.15 KXH26867.1 - 5e-07 28.7 0.0 0.0048 15.6 0.0 3.0 2 1 0 2 2 2 2 Chitin synthase Polysacc_deac_1 PF01522.21 KXH26867.1 - 1.1e-06 28.5 0.0 7.6e-06 25.8 0.0 2.3 2 0 0 2 2 2 1 Polysaccharide deacetylase Glyco_tranf_2_2 PF10111.9 KXH26867.1 - 0.0049 16.4 0.1 0.0083 15.6 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Cellulose_synt PF03552.14 KXH26867.1 - 0.052 12.0 0.1 0.11 11.0 0.0 1.4 2 0 0 2 2 2 0 Cellulose synthase Glyco_tranf_2_4 PF13704.6 KXH26867.1 - 0.06 13.9 0.1 0.13 12.8 0.1 1.6 1 0 0 1 1 1 0 Glycosyl transferase family 2 COesterase PF00135.28 KXH26869.1 - 4.9e-76 256.6 0.0 9e-76 255.8 0.0 1.3 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXH26869.1 - 0.00013 21.9 0.6 0.0013 18.7 0.6 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Homeodomain PF00046.29 KXH26870.1 - 1.2e-12 47.4 3.5 2.4e-12 46.5 3.5 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KXH26870.1 - 0.0012 18.7 0.1 0.003 17.4 0.1 1.8 1 0 0 1 1 1 1 Homeobox KN domain NARP1 PF12569.8 KXH26870.1 - 0.32 9.9 8.9 0.45 9.4 8.9 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 V_ATPase_I PF01496.19 KXH26870.1 - 0.34 8.8 3.8 0.47 8.3 3.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SPARC_Ca_bdg PF10591.9 KXH26870.1 - 0.38 11.1 2.1 0.84 10.0 2.1 1.5 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region Remorin_C PF03763.13 KXH26870.1 - 1 9.3 12.5 1.9 8.4 12.5 1.4 1 0 0 1 1 1 0 Remorin, C-terminal region HAD_2 PF13419.6 KXH26872.1 - 7.9e-20 71.7 0.0 1e-19 71.3 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KXH26872.1 - 3.1e-09 37.4 0.1 0.00017 21.9 0.0 2.2 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 KXH26872.1 - 2.1e-06 28.3 0.0 2.7e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KXH26872.1 - 0.00014 21.9 0.0 0.00024 21.1 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like GHL6 PF14871.6 KXH26872.1 - 0.037 14.2 0.0 0.09 12.9 0.0 1.6 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase 6 Hydrolase_6 PF13344.6 KXH26872.1 - 0.04 14.0 0.0 13 6.0 0.0 2.5 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase GN3L_Grn1 PF08701.11 KXH26873.1 - 5e-25 87.4 20.4 9.3e-25 86.5 20.4 1.5 1 0 0 1 1 1 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.23 KXH26873.1 - 2.8e-17 62.8 0.2 7.6e-13 48.5 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KXH26873.1 - 4e-08 33.3 0.1 3.2e-07 30.4 0.1 2.2 1 1 0 1 1 1 1 RsgA GTPase Dynamin_N PF00350.23 KXH26873.1 - 8e-06 26.0 7.5 0.036 14.1 0.5 3.9 4 0 0 4 4 4 2 Dynamin family GTP_EFTU PF00009.27 KXH26873.1 - 1.1e-05 25.0 0.0 0.031 13.8 0.0 2.5 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 KXH26873.1 - 0.00085 18.9 0.3 0.016 14.8 0.1 2.5 2 1 0 2 2 2 1 Ferrous iron transport protein B Nuc_deoxyri_tr2 PF15891.5 KXH26873.1 - 0.0081 16.5 0.8 0.58 10.5 0.0 2.6 2 0 0 2 2 2 1 Nucleoside 2-deoxyribosyltransferase like MeaB PF03308.16 KXH26873.1 - 0.032 13.2 4.5 0.081 11.9 0.0 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AIG1 PF04548.16 KXH26873.1 - 0.036 13.4 0.1 0.11 11.8 0.0 1.8 2 0 0 2 2 2 0 AIG1 family Latrophilin PF02354.16 KXH26873.1 - 0.04 13.0 1.1 0.059 12.4 1.1 1.3 1 0 0 1 1 1 0 Latrophilin Cytoplasmic C-terminal region Roc PF08477.13 KXH26873.1 - 0.084 13.1 0.1 8.3 6.7 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 KXH26873.1 - 0.59 10.5 0.0 0.59 10.5 0.0 3.4 2 1 0 2 2 2 0 AAA ATPase domain BUD22 PF09073.10 KXH26873.1 - 1.7 7.9 21.6 2.9 7.1 21.6 1.3 1 0 0 1 1 1 0 BUD22 RRN3 PF05327.11 KXH26873.1 - 4.2 5.8 9.2 7 5.1 9.2 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 SinI PF08671.10 KXH26875.1 - 0.013 15.3 0.2 0.027 14.3 0.2 1.6 1 0 0 1 1 1 0 Anti-repressor SinI PI31_Prot_C PF08577.11 KXH26875.1 - 4.5 8.5 9.6 3.5 8.9 0.7 3.3 1 1 2 3 3 3 0 PI31 proteasome regulator RNB PF00773.19 KXH26876.1 - 1.9e-98 329.8 0.1 2.9e-98 329.2 0.1 1.3 1 0 0 1 1 1 1 RNB domain Rrp44_S1 PF17215.3 KXH26876.1 - 2.9e-32 110.5 0.2 9.4e-32 108.8 0.2 1.9 1 0 0 1 1 1 1 S1 domain Rrp44_CSD1 PF17216.3 KXH26876.1 - 1e-26 93.4 0.0 3.6e-26 91.6 0.0 1.9 1 1 0 1 1 1 1 Rrp44-like cold shock domain OB_Dis3 PF17849.1 KXH26876.1 - 6e-20 71.0 0.0 1.6e-19 69.7 0.0 1.8 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) PIN_4 PF13638.6 KXH26876.1 - 3.6e-12 46.7 0.2 9.5e-12 45.3 0.2 1.8 1 0 0 1 1 1 1 PIN domain CSD2 PF17876.1 KXH26876.1 - 1.3e-07 31.7 1.5 0.0028 17.8 0.0 3.4 4 0 0 4 4 4 2 Cold shock domain Dis3l2_C_term PF17877.1 KXH26876.1 - 0.0082 16.5 0.0 0.032 14.6 0.0 2.0 1 0 0 1 1 1 1 DIS3-like exonuclease 2 C terminal FGAR-AT_N PF18076.1 KXH26877.1 - 0.13 12.2 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Formylglycinamide ribonucleotide amidotransferase N-terminal CRC_subunit PF08624.10 KXH26878.1 - 1.1e-51 174.8 0.0 1.6e-51 174.3 0.0 1.2 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit CBFD_NFYB_HMF PF00808.23 KXH26879.1 - 5e-11 42.7 0.0 9.9e-11 41.8 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KXH26879.1 - 8.2e-07 29.5 0.1 8.2e-07 29.5 0.1 2.2 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 KXH26879.1 - 0.0035 17.4 0.0 0.0073 16.4 0.0 1.5 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Paf1 PF03985.13 KXH26879.1 - 0.041 12.9 13.9 0.068 12.2 13.9 1.4 1 0 0 1 1 1 0 Paf1 TAFII28 PF04719.14 KXH26879.1 - 0.087 12.9 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 hTAFII28-like protein conserved region CDC27 PF09507.10 KXH26879.1 - 0.46 9.8 34.3 0.12 11.8 12.9 2.1 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 Cwf_Cwc_15 PF04889.12 KXH26879.1 - 2.1 8.0 24.0 0.25 11.1 18.5 2.0 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 KXH26879.1 - 3.9 6.7 17.8 7 5.9 17.8 1.5 1 0 0 1 1 1 0 NOA36 protein Cortexin PF11057.8 KXH26880.1 - 0.03 14.2 0.1 0.13 12.1 0.1 2.0 2 0 0 2 2 2 0 Cortexin of kidney CD34_antigen PF06365.12 KXH26880.1 - 0.22 11.1 0.0 0.32 10.6 0.0 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family Pkinase PF00069.25 KXH26963.1 - 3.4e-20 72.5 0.0 1.2e-19 70.7 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXH26963.1 - 5.9e-14 52.0 0.0 2.9e-08 33.3 0.0 2.4 1 1 1 2 2 2 2 Protein tyrosine kinase Sec34 PF04136.15 KXH26964.1 - 3.1e-50 169.9 3.5 3.6e-50 169.7 1.2 2.3 2 0 0 2 2 2 1 Sec34-like family RCC1 PF00415.18 KXH26965.1 - 5.6e-32 110.1 7.2 2.5e-10 40.8 0.0 8.1 7 2 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KXH26965.1 - 7.1e-20 70.3 16.6 2.3e-10 40.0 0.0 7.1 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat Y_phosphatase PF00102.27 KXH26966.1 - 2.9e-47 161.2 0.0 4.9e-47 160.5 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 KXH26966.1 - 0.0057 16.8 0.0 0.013 15.6 0.0 1.6 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 KXH26966.1 - 0.0087 16.0 0.0 0.013 15.5 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 KXH26966.1 - 0.018 14.9 0.0 0.031 14.1 0.0 1.4 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Folliculin PF11704.8 KXH26967.1 - 4.4e-61 206.0 0.2 3.4e-60 203.1 0.0 2.3 2 1 0 2 2 2 1 Vesicle coat protein involved in Golgi to plasma membrane transport AAA PF00004.29 KXH26968.1 - 2.4e-45 154.2 0.6 7.7e-45 152.6 0.0 2.1 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KXH26968.1 - 1.2e-10 41.2 0.1 7.6e-10 38.6 0.0 2.3 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 KXH26968.1 - 2.3e-08 34.1 0.8 6.6e-08 32.6 0.1 2.2 2 2 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KXH26968.1 - 5.3e-08 33.2 0.0 1.1e-07 32.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KXH26968.1 - 2.8e-07 31.1 0.6 3.7e-05 24.2 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain DUF815 PF05673.13 KXH26968.1 - 3.2e-06 26.5 0.0 6.9e-06 25.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 KXH26968.1 - 3.4e-05 24.1 0.9 0.0088 16.3 0.1 2.7 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 KXH26968.1 - 0.00024 20.9 0.0 0.00073 19.3 0.0 1.8 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 KXH26968.1 - 0.00047 20.7 0.0 0.0013 19.3 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_28 PF13521.6 KXH26968.1 - 0.00067 19.9 0.0 0.0014 18.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KXH26968.1 - 0.00086 18.9 0.1 0.0032 17.0 0.1 1.8 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_lid_3 PF17862.1 KXH26968.1 - 0.00089 19.0 0.0 0.002 17.9 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain TIP49 PF06068.13 KXH26968.1 - 0.0011 18.3 0.0 0.002 17.4 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain TsaE PF02367.17 KXH26968.1 - 0.0014 18.7 0.0 0.019 15.0 0.0 2.2 1 1 1 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 KXH26968.1 - 0.002 18.2 0.1 0.0078 16.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KXH26968.1 - 0.0021 18.4 0.0 0.0046 17.3 0.0 1.6 1 0 0 1 1 1 1 RNA helicase NTPase_1 PF03266.15 KXH26968.1 - 0.0032 17.4 0.0 0.015 15.2 0.0 2.0 2 0 0 2 2 2 1 NTPase NACHT PF05729.12 KXH26968.1 - 0.004 17.1 0.5 0.12 12.3 0.0 3.0 3 1 0 4 4 3 1 NACHT domain AAA_30 PF13604.6 KXH26968.1 - 0.0051 16.6 1.3 0.013 15.2 0.1 2.3 2 1 0 2 2 2 1 AAA domain AAA_3 PF07726.11 KXH26968.1 - 0.0056 16.5 0.0 0.018 14.9 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 KXH26968.1 - 0.0071 15.7 0.2 0.016 14.6 0.1 1.7 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 KXH26968.1 - 0.0081 16.3 0.0 0.019 15.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KXH26968.1 - 0.0091 15.7 0.1 0.03 14.0 0.0 1.9 2 0 0 2 2 2 1 IstB-like ATP binding protein Viral_Hsp90 PF03225.14 KXH26968.1 - 0.013 14.1 0.0 0.019 13.5 0.0 1.2 1 0 0 1 1 1 0 Viral heat shock protein Hsp90 homologue TniB PF05621.11 KXH26968.1 - 0.013 14.9 0.0 0.5 9.7 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein AAA_24 PF13479.6 KXH26968.1 - 0.022 14.5 0.2 0.055 13.2 0.2 1.8 1 1 0 1 1 1 0 AAA domain AAA_11 PF13086.6 KXH26968.1 - 0.036 13.8 0.1 0.14 12.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain Bac_DnaA PF00308.18 KXH26968.1 - 0.039 13.8 0.0 0.077 12.8 0.0 1.5 1 0 0 1 1 1 0 Bacterial dnaA protein AFG1_ATPase PF03969.16 KXH26968.1 - 0.04 12.8 0.1 0.13 11.1 0.0 1.8 2 0 0 2 2 2 0 AFG1-like ATPase ATPase PF06745.13 KXH26968.1 - 0.041 13.2 1.3 0.56 9.5 0.0 2.5 3 0 0 3 3 3 0 KaiC ATPase_2 PF01637.18 KXH26968.1 - 0.042 13.8 1.0 0.34 10.8 0.0 2.6 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea AAA_25 PF13481.6 KXH26968.1 - 0.061 12.9 1.0 0.19 11.2 0.3 2.1 2 1 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 KXH26968.1 - 0.068 12.9 0.2 1.3 8.7 0.0 2.5 2 1 0 2 2 2 0 Sigma-54 interaction domain Zeta_toxin PF06414.12 KXH26968.1 - 0.088 12.1 0.1 0.22 10.8 0.0 1.7 2 0 0 2 2 1 0 Zeta toxin AAA_19 PF13245.6 KXH26968.1 - 0.13 12.6 0.1 0.37 11.1 0.1 1.7 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 KXH26968.1 - 0.14 11.7 0.0 0.34 10.5 0.0 1.6 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain SPACA9 PF15120.6 KXH26968.1 - 0.15 11.8 1.0 14 5.4 0.0 2.2 2 0 0 2 2 2 0 Sperm acrosome-associated protein 9 AAA_29 PF13555.6 KXH26968.1 - 0.16 11.7 0.0 0.33 10.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Parvo_NS1 PF01057.17 KXH26968.1 - 0.2 10.7 0.0 0.37 9.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF3530 PF12048.8 KXH26969.1 - 0.012 15.0 0.1 0.012 15.0 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) SSFA2_C PF14723.6 KXH26969.1 - 0.087 12.7 2.3 0.1 12.5 2.3 1.2 1 0 0 1 1 1 0 Sperm-specific antigen 2 C-terminus Mis14 PF08641.12 KXH26970.1 - 9.9e-16 58.3 0.2 2.4e-15 57.0 0.0 1.7 2 0 0 2 2 2 1 Kinetochore protein Mis14 like bZIP_1 PF00170.21 KXH26970.1 - 0.022 14.8 0.5 0.44 10.7 0.2 2.1 2 0 0 2 2 2 0 bZIP transcription factor Jnk-SapK_ap_N PF09744.9 KXH26970.1 - 0.039 14.2 0.3 0.18 12.0 0.3 1.9 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 DNTTIP1_dimer PF18192.1 KXH26970.1 - 0.072 13.5 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 DNTTIP1 dimerisation domain Nnf1 PF03980.14 KXH26970.1 - 1.1 9.6 4.8 15 6.1 0.4 2.1 2 0 0 2 2 2 0 Nnf1 SnoaL PF07366.12 KXH26978.1 - 6.8e-19 67.9 0.0 1.5e-08 34.5 0.0 2.4 2 1 0 2 2 2 2 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 KXH26978.1 - 0.0011 19.6 0.0 0.15 12.7 0.0 2.5 2 1 0 2 2 2 1 SnoaL-like domain DUF148 PF02520.17 KXH26978.1 - 0.15 12.2 0.1 0.24 11.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF148 TRAPP PF04051.16 KXH26979.1 - 1.4e-38 131.9 0.0 1.6e-38 131.7 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component DUF4094 PF13334.6 KXH26987.1 - 0.23 11.9 1.2 0.4 11.1 1.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4094) Zn_clus PF00172.18 KXH26991.1 - 1.2e-05 25.4 11.5 1.9e-05 24.6 11.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Spt20 PF12090.8 KXH26991.1 - 1.9 8.0 11.0 3.6 7.1 11.0 1.4 1 0 0 1 1 1 0 Spt20 family NAD_binding_1 PF00175.21 KXH26992.1 - 2.2e-10 41.2 0.0 3.9e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Globin PF00042.22 KXH26992.1 - 4.1e-10 40.2 0.0 6.4e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Globin NAD_binding_6 PF08030.12 KXH26992.1 - 6.9e-06 26.3 0.0 2.2e-05 24.6 0.0 1.7 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_6 PF00970.24 KXH26992.1 - 3.8e-05 23.9 0.0 7.5e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Protoglobin PF11563.8 KXH26992.1 - 0.00028 20.8 0.1 0.00048 20.1 0.1 1.4 1 0 0 1 1 1 1 Protoglobin Glycos_transf_1 PF00534.20 KXH26994.1 - 4.5e-20 71.9 0.0 1.1e-19 70.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KXH26994.1 - 1.6e-13 51.2 0.0 2.7e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 KXH26994.1 - 0.043 14.2 0.0 0.15 12.5 0.0 1.9 1 0 0 1 1 1 0 Glycosyl transferases group 1 Methyltransf_23 PF13489.6 KXH26996.1 - 1.1e-17 64.3 0.0 2.9e-17 63.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH26996.1 - 1.9e-12 47.6 0.0 3.6e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH26996.1 - 6.6e-12 46.0 0.0 1.6e-11 44.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH26996.1 - 1.2e-05 25.2 0.0 0.00014 21.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH26996.1 - 0.00022 21.9 0.0 0.0017 19.1 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXH26996.1 - 0.0041 16.5 0.0 0.027 13.8 0.0 1.9 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 KXH26996.1 - 0.014 14.9 0.0 0.028 13.9 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_2 PF00891.18 KXH26996.1 - 0.015 14.6 0.0 0.025 13.9 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain CMAS PF02353.20 KXH26996.1 - 0.024 13.9 0.0 0.043 13.1 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase FtsJ PF01728.19 KXH26996.1 - 0.048 13.8 0.0 0.4 10.8 0.0 2.0 2 0 0 2 2 2 0 FtsJ-like methyltransferase MTS PF05175.14 KXH26996.1 - 0.09 12.3 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain SET PF00856.28 KXH26997.1 - 5.3e-06 26.9 0.0 9e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 SET domain Beta-lactamase PF00144.24 KXH26998.1 - 5.7e-54 183.6 0.4 7.4e-54 183.2 0.4 1.1 1 0 0 1 1 1 1 Beta-lactamase Beta-lactamase2 PF13354.6 KXH26998.1 - 0.00045 19.9 0.0 0.42 10.2 0.0 2.2 2 0 0 2 2 2 2 Beta-lactamase enzyme family Peptidase_S11 PF00768.20 KXH26998.1 - 0.15 11.4 0.1 0.29 10.5 0.1 1.3 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase MFS_1 PF07690.16 KXH26999.1 - 6.4e-35 120.7 29.7 1.3e-34 119.7 29.1 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH26999.1 - 8.6e-12 44.6 21.7 1.3e-11 44.1 21.7 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.20 KXH26999.1 - 0.44 8.8 9.2 0.027 12.8 2.9 2.1 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Fungal_trans_2 PF11951.8 KXH27001.1 - 4.5e-52 177.2 2.4 5.5e-52 176.9 2.4 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH27001.1 - 1.9e-07 31.1 9.1 4.3e-07 30.0 9.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Proton_antipo_M PF00361.20 KXH27001.1 - 0.1 11.8 0.3 0.18 11.0 0.3 1.3 1 0 0 1 1 1 0 Proton-conducting membrane transporter DUF2284 PF10050.9 KXH27001.1 - 1.1 9.0 5.6 0.7 9.6 2.6 2.0 2 0 0 2 2 2 0 Predicted metal-binding protein (DUF2284) Aldolase_II PF00596.21 KXH27002.1 - 1.7e-47 161.8 0.2 2.2e-47 161.4 0.2 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain CDCA PF18484.1 KXH27002.1 - 0.12 12.2 0.2 0.2 11.5 0.2 1.3 1 0 0 1 1 1 0 Cadmium carbonic anhydrase repeat IRF-3 PF10401.9 KXH27003.1 - 0.18 11.6 0.0 0.28 11.0 0.0 1.2 1 0 0 1 1 1 0 Interferon-regulatory factor 3 AA_permease PF00324.21 KXH27004.1 - 3.9e-117 391.8 37.1 4.8e-117 391.5 37.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KXH27004.1 - 2.1e-31 109.2 41.9 2.5e-31 109.0 41.9 1.0 1 0 0 1 1 1 1 Amino acid permease PEP_hydrolase PF09370.10 KXH27004.1 - 0.14 11.3 0.0 7.7 5.6 0.0 2.2 2 0 0 2 2 2 0 Phosphoenolpyruvate hydrolase-like Arginase PF00491.21 KXH27005.1 - 3.2e-74 249.9 0.1 2.5e-50 171.5 0.0 2.0 1 1 1 2 2 2 2 Arginase family COesterase PF00135.28 KXH27006.1 - 7.3e-65 219.8 0.1 9.2e-65 219.5 0.1 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXH27006.1 - 0.00078 19.4 0.4 0.002 18.0 0.1 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold EthD PF07110.11 KXH27007.1 - 3.1e-22 79.5 0.1 5.3e-22 78.8 0.1 1.4 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 KXH27007.1 - 5e-07 30.2 0.2 2.6e-06 27.9 0.2 1.9 1 1 0 1 1 1 1 Methylmuconolactone methyl-isomerase TA0956 PF11513.8 KXH27009.1 - 0.026 14.8 0.0 0.065 13.5 0.0 1.6 1 0 0 1 1 1 0 Thermoplasma acidophilum protein TA0956 HeLo PF14479.6 KXH27009.1 - 0.054 13.3 1.1 0.11 12.3 1.1 1.6 1 0 0 1 1 1 0 Prion-inhibition and propagation CLASP_N PF12348.8 KXH27011.1 - 3.7e-06 26.7 0.0 0.00057 19.5 0.0 2.4 2 0 0 2 2 2 1 CLASP N terminal HEAT PF02985.22 KXH27011.1 - 1.6e-05 24.7 0.7 1.7 9.1 0.1 4.6 4 0 0 4 4 4 1 HEAT repeat Cnd1 PF12717.7 KXH27011.1 - 5.1e-05 23.4 0.1 0.015 15.3 0.0 2.3 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KXH27011.1 - 0.00044 20.6 2.4 0.11 12.9 0.1 3.6 3 2 0 3 3 3 1 HEAT repeats Adaptin_N PF01602.20 KXH27011.1 - 0.037 12.6 0.6 1.9 7.0 0.2 2.6 2 2 0 2 2 2 0 Adaptin N terminal region TAN PF11640.8 KXH27011.1 - 0.1 12.7 1.4 0.15 12.2 0.0 2.0 2 0 0 2 2 2 0 Telomere-length maintenance and DNA damage repair DUF4763 PF15960.5 KXH27011.1 - 0.18 11.1 3.3 0.12 11.7 1.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4763) Jnk-SapK_ap_N PF09744.9 KXH27011.1 - 0.52 10.5 12.2 1.4 9.1 12.2 1.7 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 HEAT_EZ PF13513.6 KXH27011.1 - 0.66 10.5 4.1 1.5 9.4 0.6 3.3 4 0 0 4 4 2 0 HEAT-like repeat HALZ PF02183.18 KXH27011.1 - 0.69 10.2 8.7 1.6 9.0 1.2 3.0 3 0 0 3 3 2 0 Homeobox associated leucine zipper Fez1 PF06818.15 KXH27011.1 - 0.98 9.8 7.7 2.6 8.4 7.7 1.7 1 0 0 1 1 1 0 Fez1 APG6_N PF17675.1 KXH27011.1 - 1.2 9.7 11.8 7.1 7.2 11.8 2.3 1 1 0 1 1 1 0 Apg6 coiled-coil region HAUS-augmin3 PF14932.6 KXH27011.1 - 1.3 8.5 7.9 7.1 6.1 7.9 2.0 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 Spc7 PF08317.11 KXH27011.1 - 1.5 7.6 8.9 0.92 8.3 5.3 1.9 1 1 0 1 1 1 0 Spc7 kinetochore protein ADIP PF11559.8 KXH27011.1 - 1.6 8.8 11.8 4.7 7.3 11.8 1.8 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding KLRAQ PF10205.9 KXH27011.1 - 1.9 8.7 7.5 19 5.6 2.1 2.7 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein DUF4407 PF14362.6 KXH27011.1 - 2 7.7 6.7 1.1 8.6 3.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Mod_r PF07200.13 KXH27011.1 - 2.1 8.4 8.3 5.6 7.1 8.3 1.7 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein CorA PF01544.18 KXH27011.1 - 2.8 7.2 8.9 5.2 6.3 8.9 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein SHE3 PF17078.5 KXH27011.1 - 4.5 6.9 10.5 8.9 6.0 10.5 1.4 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 YabA PF06156.13 KXH27011.1 - 5.8 7.6 7.0 60 4.3 7.0 2.5 1 1 0 1 1 1 0 Initiation control protein YabA DUF1640 PF07798.11 KXH27011.1 - 6.2 6.8 16.8 2.3 8.2 1.2 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1640) MRP-L46 PF11788.8 KXH27011.1 - 6.5 7.5 7.2 1.6 9.4 3.0 2.1 2 0 0 2 2 1 0 39S mitochondrial ribosomal protein L46 DUF3584 PF12128.8 KXH27011.1 - 6.9 4.0 9.8 11 3.4 9.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) MFS_1 PF07690.16 KXH27050.1 - 3.1e-34 118.5 28.7 4e-34 118.1 28.7 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH27050.1 - 1.2e-14 54.1 6.9 1.3e-14 53.9 6.9 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter PTR2 PF00854.21 KXH27050.1 - 0.015 14.2 0.4 0.015 14.2 0.4 2.3 3 0 0 3 3 3 0 POT family UPF0093 PF03653.13 KXH27050.1 - 0.11 12.8 0.0 0.11 12.8 0.0 2.3 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0093) Prefoldin_2 PF01920.20 KXH27051.1 - 1.6e-26 92.3 10.2 1.6e-26 92.3 10.2 1.4 2 0 0 2 2 2 1 Prefoldin subunit MMTV_SAg PF01054.17 KXH27051.1 - 0.0057 16.2 1.2 1.6 8.2 0.1 2.1 1 1 1 2 2 2 2 Mouse mammary tumour virus superantigen UPF0242 PF06785.11 KXH27051.1 - 0.011 15.9 8.0 0.013 15.6 8.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus PI3K_P85_iSH2 PF16454.5 KXH27051.1 - 0.035 13.7 9.5 0.11 12.1 9.5 1.7 1 1 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Syntaxin-6_N PF09177.11 KXH27051.1 - 0.044 14.3 5.5 1.4 9.5 1.8 2.2 2 0 0 2 2 2 0 Syntaxin 6, N-terminal bZIP_1 PF00170.21 KXH27051.1 - 0.075 13.1 1.2 0.075 13.1 1.2 2.2 2 0 0 2 2 2 0 bZIP transcription factor DUF1664 PF07889.12 KXH27051.1 - 0.14 12.2 0.2 0.14 12.2 0.2 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) XhlA PF10779.9 KXH27051.1 - 0.25 11.5 0.3 0.25 11.5 0.3 2.3 2 0 0 2 2 2 0 Haemolysin XhlA V_ATPase_I PF01496.19 KXH27051.1 - 0.37 8.7 3.9 0.46 8.3 3.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family MIT_C PF16565.5 KXH27051.1 - 0.96 9.4 4.6 1.8 8.6 0.2 2.1 1 1 1 2 2 2 0 Phospholipase D-like domain at C-terminus of MIT MtrG PF04210.13 KXH27051.1 - 1.4 8.9 3.4 0.48 10.3 0.2 1.9 2 1 1 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, subunit G Spc24 PF08286.11 KXH27051.1 - 8.8 6.6 13.4 0.69 10.2 1.0 2.2 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 CENP-W PF15510.6 KXH27052.1 - 0.0076 16.4 0.0 0.0089 16.2 0.0 1.2 1 0 0 1 1 1 1 CENP-W protein PRTP PF01366.18 KXH27053.1 - 0.36 8.8 8.0 0.52 8.3 8.0 1.3 1 0 0 1 1 1 0 Herpesvirus processing and transport protein ARGLU PF15346.6 KXH27053.1 - 1.9 8.4 15.7 0.18 11.6 10.8 1.9 2 0 0 2 2 2 0 Arginine and glutamate-rich 1 FAD_binding_4 PF01565.23 KXH27054.1 - 1e-19 70.7 3.3 1e-19 70.7 3.3 2.0 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 KXH27054.1 - 8e-14 51.5 1.0 2.1e-13 50.2 1.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like Abhydrolase_3 PF07859.13 KXH27060.1 - 4.5e-20 72.4 0.1 6.2e-20 72.0 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KXH27060.1 - 2.5e-07 30.0 0.0 3.6e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Glyco_hydro_88 PF07470.13 KXH27061.1 - 1.5e-63 214.9 4.3 1.9e-63 214.6 4.3 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Glyco_hydro_127 PF07944.12 KXH27061.1 - 0.002 16.7 0.0 0.0029 16.2 0.0 1.2 1 0 0 1 1 1 1 Beta-L-arabinofuranosidase, GH127 C5-epim_C PF06662.13 KXH27061.1 - 0.0024 17.4 1.4 0.065 12.7 0.1 3.0 2 1 1 3 3 3 1 D-glucuronyl C5-epimerase C-terminus ThiF PF00899.21 KXH27075.1 - 1.5e-41 142.4 0.0 2.4e-41 141.7 0.0 1.2 1 0 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 KXH27075.1 - 1.1e-06 29.0 0.1 2.5e-06 27.8 0.1 1.6 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 KXH27075.1 - 0.008 16.4 0.2 0.033 14.4 0.1 2.1 2 0 0 2 2 2 1 TrkA-N domain NAD_binding_7 PF13241.6 KXH27075.1 - 0.01 16.3 0.0 0.029 14.8 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding MAF_flag10 PF01973.18 KXH27075.1 - 0.021 14.5 0.0 0.088 12.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function DUF115 UDPG_MGDP_dh_N PF03721.14 KXH27075.1 - 0.027 14.1 0.2 0.049 13.2 0.2 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TPR_14 PF13428.6 KXH27076.1 - 0.11 13.4 0.4 0.11 13.4 0.4 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat BAR PF03114.18 KXH27077.1 - 2.2e-13 50.4 0.1 3.1e-13 49.9 0.1 1.2 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 KXH27077.1 - 6.9e-11 41.6 0.2 1.7e-10 40.3 0.2 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KXH27077.1 - 7.7e-10 38.5 0.0 1.8e-09 37.3 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KXH27077.1 - 8e-09 35.1 0.0 1.9e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain DUF3104 PF11302.8 KXH27077.1 - 0.083 12.6 0.1 0.18 11.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3104) DUF2439 PF10382.9 KXH27078.1 - 1.2e-26 92.8 0.1 2.7e-26 91.7 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) DUF2304 PF10066.9 KXH27079.1 - 0.027 14.7 0.2 0.046 13.9 0.2 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2304) SPAN-X PF07458.12 KXH27079.1 - 0.22 12.0 2.8 0.77 10.3 2.8 1.8 1 0 0 1 1 1 0 Sperm protein associated with nucleus, mapped to X chromosome Zn_clus PF00172.18 KXH27079.1 - 0.3 11.2 9.6 0.64 10.2 9.6 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain dCMP_cyt_deam_1 PF00383.23 KXH27080.1 - 6.7e-22 77.3 0.0 1.7e-21 76.0 0.0 1.6 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KXH27080.1 - 1.3e-18 67.1 0.1 3.1e-08 33.5 0.0 2.2 2 0 0 2 2 2 2 MafB19-like deaminase Bd3614-deam PF14439.6 KXH27080.1 - 0.00042 20.4 1.7 0.012 15.7 0.0 2.7 3 0 0 3 3 3 1 Bd3614-like deaminase Xan_ur_permease PF00860.20 KXH27081.1 - 1e-26 93.6 34.2 1.5e-26 93.0 29.9 2.5 2 1 0 2 2 2 1 Permease family MFS_MOT1 PF16983.5 KXH27081.1 - 3.9 7.9 23.0 0.069 13.5 4.8 3.4 2 1 0 3 3 3 0 Molybdate transporter of MFS superfamily Na_H_Exchanger PF00999.21 KXH27084.1 - 2.5e-59 201.0 48.0 3.6e-59 200.5 48.0 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family MOSC PF03473.17 KXH27091.1 - 9.1e-23 80.7 0.0 1.6e-22 79.9 0.0 1.4 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 KXH27091.1 - 7.2e-12 45.2 0.0 1.5e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain SMC_N PF02463.19 KXH27092.1 - 1.7e-69 233.7 7.6 5.3e-68 228.8 7.6 2.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KXH27092.1 - 3.8e-21 75.6 1.1 8.2e-20 71.3 0.2 3.1 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 KXH27092.1 - 6.6e-09 36.0 10.4 0.00016 21.6 0.2 3.7 4 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KXH27092.1 - 0.00013 21.7 0.1 0.0003 20.5 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain GAS PF13851.6 KXH27092.1 - 0.0028 17.0 7.5 0.0028 17.0 7.5 7.3 3 2 4 7 7 7 2 Growth-arrest specific micro-tubule binding HIP1_clath_bdg PF16515.5 KXH27092.1 - 0.017 15.8 8.2 0.017 15.8 8.2 9.2 3 2 6 9 9 9 0 Clathrin-binding domain of Huntingtin-interacting protein 1 HSBP1 PF06825.12 KXH27092.1 - 0.032 14.1 0.5 0.032 14.1 0.5 4.0 4 0 0 4 4 4 0 Heat shock factor binding protein 1 FDX-ACB PF03147.14 KXH27092.1 - 1.9 8.9 11.9 0.62 10.5 2.3 4.2 4 0 0 4 4 4 0 Ferredoxin-fold anticodon binding domain INCENP_ARK-bind PF03941.15 KXH27093.1 - 1.2e-18 66.8 0.9 1.2e-18 66.8 0.9 3.8 5 0 0 5 5 5 1 Inner centromere protein, ARK binding region ORC4_C PF14629.6 KXH27094.1 - 1e-65 221.2 0.0 1.8e-65 220.4 0.0 1.4 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.6 KXH27094.1 - 9.7e-14 52.1 1.1 3.9e-13 50.1 0.2 2.3 2 0 0 2 2 2 1 AAA ATPase domain PHD PF00628.29 KXH27094.1 - 4.4e-12 45.7 6.4 8e-12 44.9 6.4 1.4 1 0 0 1 1 1 1 PHD-finger AAA_22 PF13401.6 KXH27094.1 - 1.3e-09 38.4 0.0 4.7e-09 36.6 0.0 1.9 2 0 0 2 2 1 1 AAA domain PHD_2 PF13831.6 KXH27094.1 - 6.5e-09 35.2 1.9 1.4e-08 34.1 1.9 1.6 1 0 0 1 1 1 1 PHD-finger AAA PF00004.29 KXH27094.1 - 9.7e-09 35.8 0.0 3.2e-08 34.1 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 KXH27094.1 - 6.8e-08 32.6 0.0 2.2e-07 30.9 0.0 1.9 1 1 0 1 1 1 1 NACHT domain KAP_NTPase PF07693.14 KXH27094.1 - 9.4e-06 25.1 0.1 4e-05 23.0 0.0 1.8 1 1 1 2 2 2 1 KAP family P-loop domain AAA_19 PF13245.6 KXH27094.1 - 1.3e-05 25.6 0.3 5.9e-05 23.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 KXH27094.1 - 4.1e-05 23.6 0.0 8.7e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_14 PF13173.6 KXH27094.1 - 5.5e-05 23.2 0.0 0.00055 20.0 0.0 2.7 3 1 0 3 3 2 1 AAA domain NB-ARC PF00931.22 KXH27094.1 - 0.00022 20.5 0.1 0.00048 19.4 0.1 1.5 1 0 0 1 1 1 1 NB-ARC domain AAA_30 PF13604.6 KXH27094.1 - 0.00036 20.3 0.0 0.001 18.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain TniB PF05621.11 KXH27094.1 - 0.00094 18.6 0.1 0.016 14.7 0.1 2.2 1 1 0 1 1 1 1 Bacterial TniB protein SMC_N PF02463.19 KXH27094.1 - 0.0018 17.8 0.0 0.0044 16.5 0.0 1.6 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain C1_1 PF00130.22 KXH27094.1 - 0.0019 18.0 0.7 0.0049 16.7 0.7 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-HC5HC2H PF13771.6 KXH27094.1 - 0.0087 16.3 1.0 0.021 15.1 1.0 1.6 1 0 0 1 1 1 1 PHD-like zinc-binding domain ORC2 PF04084.14 KXH27094.1 - 0.016 14.1 0.2 0.17 10.8 0.0 2.1 2 0 0 2 2 2 0 Origin recognition complex subunit 2 zf-PHD-like PF15446.6 KXH27094.1 - 0.02 14.5 2.3 0.059 13.0 2.3 1.9 1 1 0 1 1 1 0 PHD/FYVE-zinc-finger like domain ABC_tran PF00005.27 KXH27094.1 - 0.02 15.4 0.2 0.082 13.4 0.0 2.1 2 0 0 2 2 1 0 ABC transporter ATP-synt_ab PF00006.25 KXH27094.1 - 0.021 14.5 0.0 0.048 13.3 0.0 1.5 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF815 PF05673.13 KXH27094.1 - 0.023 13.9 0.0 0.042 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) zf-HC5HC2H_2 PF13832.6 KXH27094.1 - 0.024 14.8 0.7 0.05 13.8 0.7 1.5 1 0 0 1 1 1 0 PHD-zinc-finger like domain PduV-EutP PF10662.9 KXH27094.1 - 0.026 14.3 0.0 0.062 13.0 0.0 1.7 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Viral_helicase1 PF01443.18 KXH27094.1 - 0.038 13.7 0.0 0.18 11.5 0.0 2.2 2 0 0 2 2 1 0 Viral (Superfamily 1) RNA helicase FYVE_2 PF02318.16 KXH27094.1 - 0.042 14.1 5.0 0.033 14.4 3.2 1.7 2 0 0 2 2 1 0 FYVE-type zinc finger Prok-RING_1 PF14446.6 KXH27094.1 - 0.052 13.5 4.2 0.14 12.2 4.2 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 AAA_29 PF13555.6 KXH27094.1 - 0.062 13.1 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.6 KXH27094.1 - 0.063 13.8 0.0 0.15 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain Bac_DnaA PF00308.18 KXH27094.1 - 0.07 12.9 0.0 2.3 8.0 0.0 2.2 2 0 0 2 2 2 0 Bacterial dnaA protein AAA_28 PF13521.6 KXH27094.1 - 0.082 13.1 0.3 0.24 11.6 0.0 2.0 2 0 0 2 2 1 0 AAA domain RNA_helicase PF00910.22 KXH27094.1 - 0.097 13.1 0.0 0.49 10.8 0.0 2.2 2 0 0 2 2 1 0 RNA helicase AAA_23 PF13476.6 KXH27094.1 - 0.1 13.1 3.3 1.9 8.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KXH27094.1 - 0.16 11.5 0.0 0.4 10.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region Zf_RING PF16744.5 KXH27094.1 - 0.29 11.3 3.7 0.75 10.0 3.7 1.7 1 0 0 1 1 1 0 KIAA1045 RING finger C1_2 PF03107.16 KXH27094.1 - 0.51 10.7 6.9 0.06 13.7 2.6 1.7 2 0 0 2 2 1 0 C1 domain zf-RING_2 PF13639.6 KXH27094.1 - 0.53 10.7 5.8 1.8 9.0 5.8 1.9 1 1 0 1 1 1 0 Ring finger domain zf-RING_9 PF13901.6 KXH27094.1 - 2.9 7.8 6.1 11 5.9 5.0 2.1 1 1 1 2 2 2 0 Putative zinc-RING and/or ribbon Terpene_synth_C PF03936.16 KXH27096.1 - 0.00024 20.5 0.0 0.00062 19.2 0.0 1.6 2 0 0 2 2 2 1 Terpene synthase family, metal binding domain TRI5 PF06330.11 KXH27096.1 - 0.0021 17.0 0.0 0.003 16.5 0.0 1.2 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) SET PF00856.28 KXH27101.1 - 2e-09 38.1 0.1 2.4e-08 34.6 0.0 2.4 2 1 0 2 2 2 1 SET domain F-box-like PF12937.7 KXH27102.1 - 0.004 17.0 0.2 0.014 15.3 0.2 2.0 1 0 0 1 1 1 1 F-box-like Kinetochor_Ybp2 PF08568.10 KXH27103.1 - 8.7e-93 311.9 0.0 1.1e-92 311.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin Glyco_transf_28 PF03033.20 KXH27104.1 - 2.7e-16 59.9 0.1 2.8e-15 56.6 0.1 2.4 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 KXH27104.1 - 7.7e-07 28.3 0.0 1.4e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase ATG_C PF09333.11 KXH27104.1 - 0.00019 21.7 0.0 0.001 19.4 0.0 2.3 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain Glyco_tran_28_C PF04101.16 KXH27104.1 - 0.0071 16.3 0.0 0.024 14.6 0.0 1.9 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain TyrRSs_C PF16714.5 KXH27105.1 - 0.16 11.8 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 Tyrosyl-tRNA synthetase C-terminal domain Zap1_zf2 PF18217.1 KXH27111.1 - 0.011 15.7 0.4 0.022 14.7 0.4 1.6 1 0 0 1 1 1 0 Zap1 zinc finger 2 Tctex-1 PF03645.13 KXH27112.1 - 0.16 12.2 2.2 0.19 12.0 0.6 1.9 1 1 1 2 2 2 0 Tctex-1 family PKD PF00801.20 KXH27114.1 - 0.0021 17.9 6.5 0.0052 16.6 1.4 3.4 3 0 0 3 3 3 1 PKD domain Lsr2 PF11774.8 KXH27114.1 - 0.93 9.7 4.7 2.1 8.5 0.0 3.3 3 0 0 3 3 3 0 Lsr2 DUF5401 PF17380.2 KXH27114.1 - 1.1 7.3 17.3 1.5 6.8 17.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) DUF2190 PF09956.9 KXH27114.1 - 3.4 8.2 6.1 2 8.9 3.3 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2190) DUF4407 PF14362.6 KXH27114.1 - 8.1 5.7 9.8 13 5.1 9.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) LamB_YcsF PF03746.16 KXH27115.1 - 5.6e-82 275.0 0.0 6.4e-82 274.8 0.0 1.0 1 0 0 1 1 1 1 LamB/YcsF family CT_A_B PF02626.15 KXH27116.1 - 5.3e-77 259.0 0.0 8.1e-77 258.4 0.0 1.3 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain A and B CPSase_L_D2 PF02786.17 KXH27116.1 - 3.4e-53 180.3 0.0 8e-53 179.1 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 KXH27116.1 - 9.4e-38 129.2 0.1 1.9e-37 128.2 0.1 1.5 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain CT_C_D PF02682.16 KXH27116.1 - 6.6e-32 110.9 0.0 1.8e-31 109.4 0.0 1.7 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain C and D Biotin_carb_C PF02785.19 KXH27116.1 - 2.7e-30 104.7 0.0 5.5e-30 103.6 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 KXH27116.1 - 8.2e-09 35.2 4.5 5.2e-08 32.6 4.0 2.7 3 0 0 3 3 3 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 KXH27116.1 - 1.3e-06 28.2 0.0 3.1e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_5 PF13549.6 KXH27116.1 - 0.0034 16.9 0.0 0.0072 15.8 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.22 KXH27116.1 - 0.0055 16.3 0.0 0.011 15.3 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 KXH27116.1 - 0.057 13.0 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 RimK-like ATP-grasp domain Fungal_trans PF04082.18 KXH27117.1 - 2.1e-08 33.5 0.0 1e-07 31.2 0.0 2.1 2 1 0 2 2 2 1 Fungal specific transcription factor domain ABC2_membrane PF01061.24 KXH27118.1 - 4.8e-27 94.7 25.8 6.6e-27 94.3 25.8 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 KXH27118.1 - 1.5e-26 93.5 0.0 2.8e-26 92.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 KXH27118.1 - 4.2e-06 26.8 0.1 7.7e-05 22.7 0.1 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 KXH27118.1 - 7.5e-05 22.4 0.3 0.00016 21.3 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KXH27118.1 - 0.0009 19.7 0.3 0.0017 18.7 0.0 1.7 2 0 0 2 2 1 1 AAA ATPase domain SMC_N PF02463.19 KXH27118.1 - 0.0025 17.3 0.0 0.0073 15.8 0.0 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KXH27118.1 - 0.004 17.0 0.0 2.6 7.7 0.0 2.3 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 KXH27118.1 - 0.008 16.6 0.0 0.044 14.2 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_13 PF13166.6 KXH27118.1 - 0.01 14.5 0.3 0.041 12.5 0.1 1.9 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KXH27118.1 - 0.012 15.9 0.0 0.025 14.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 KXH27118.1 - 0.013 15.5 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_28 PF13521.6 KXH27118.1 - 0.045 14.0 0.1 0.099 12.9 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KXH27118.1 - 0.059 13.1 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KXH27118.1 - 0.093 12.8 0.2 0.21 11.7 0.2 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase cobW PF02492.19 KXH27118.1 - 0.15 11.6 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Peptidase_S77 PF03420.13 KXH27118.1 - 0.17 11.6 0.0 0.32 10.6 0.0 1.4 1 0 0 1 1 1 0 Prohead core protein serine protease PDR_CDR PF06422.12 KXH27118.1 - 0.17 11.8 0.1 0.17 11.8 0.1 2.3 2 1 1 3 3 1 0 CDR ABC transporter NCA2 PF08637.10 KXH27118.1 - 0.42 9.7 1.1 0.83 8.8 1.1 1.4 1 0 0 1 1 1 0 ATP synthase regulation protein NCA2 ABC2_membrane_3 PF12698.7 KXH27118.1 - 0.45 9.6 28.1 0.19 10.8 24.3 2.0 1 1 1 2 2 2 0 ABC-2 family transporter protein DUF2070 PF09843.9 KXH27118.1 - 5.3 5.2 11.8 8.4 4.5 11.8 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DNApol_Exo PF18136.1 KXH27119.1 - 4.7e-105 350.8 0.0 8.7e-105 349.9 0.0 1.4 1 0 0 1 1 1 1 DNA mitochondrial polymerase exonuclease domain DNA_pol_A PF00476.20 KXH27119.1 - 1.7e-55 188.6 0.0 2.7e-55 187.9 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family A zf-C3HC4_3 PF13920.6 KXH27120.1 - 2.9e-11 43.0 7.8 4.4e-11 42.5 7.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXH27120.1 - 1.9e-08 34.0 10.3 3.3e-08 33.2 10.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KXH27120.1 - 2.8e-08 33.5 8.3 5.2e-08 32.6 8.3 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KXH27120.1 - 1.3e-07 31.8 9.0 2.2e-07 31.1 9.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KXH27120.1 - 3.1e-07 30.2 9.4 5.7e-07 29.4 9.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KXH27120.1 - 4.3e-07 29.7 9.8 7.2e-07 29.0 9.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXH27120.1 - 8.2e-07 28.9 6.3 8.4e-07 28.9 3.4 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 KXH27120.1 - 1.7e-05 24.8 3.4 2.8e-05 24.1 3.4 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 KXH27120.1 - 0.0005 19.8 5.4 0.00095 18.9 5.4 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 KXH27120.1 - 0.0021 18.3 5.2 0.0046 17.2 5.2 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 KXH27120.1 - 0.011 15.9 7.9 0.021 15.0 7.9 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.5 KXH27120.1 - 0.058 13.2 9.8 0.17 11.6 7.0 2.4 2 0 0 2 2 2 0 RING-like zinc finger TerY_C PF15616.6 KXH27120.1 - 0.063 13.4 1.8 0.12 12.5 1.8 1.3 1 0 0 1 1 1 0 TerY-C metal binding domain zf-RING_6 PF14835.6 KXH27120.1 - 0.25 11.2 2.7 0.44 10.5 2.7 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-P11 PF03854.14 KXH27120.1 - 0.8 9.4 4.8 1.5 8.6 4.8 1.4 1 0 0 1 1 1 0 P-11 zinc finger DZR PF12773.7 KXH27120.1 - 1.1 9.3 5.7 3.2 7.8 5.7 1.8 1 1 0 1 1 1 0 Double zinc ribbon RNHCP PF12647.7 KXH27120.1 - 2.7 8.0 8.2 11 6.0 8.2 2.0 1 1 0 1 1 1 0 RNHCP domain IBR PF01485.21 KXH27120.1 - 8.9 6.6 8.0 2.2 8.6 2.5 2.2 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain FYVE PF01363.21 KXH27120.1 - 9.1 6.5 8.5 43 4.3 8.4 2.0 1 1 1 2 2 2 0 FYVE zinc finger Nup192 PF11894.8 KXH27121.1 - 0 1542.9 0.0 0 1542.6 0.0 1.0 1 0 0 1 1 1 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 PI3_PI4_kinase PF00454.27 KXH27122.1 - 2.1e-49 168.6 0.0 1.2e-48 166.2 0.0 2.1 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.8 KXH27122.1 - 4.4e-36 124.3 0.0 3.1e-35 121.5 0.0 2.7 1 0 0 1 1 1 1 Telomere-length maintenance and DNA damage repair FATC PF02260.20 KXH27122.1 - 2.4e-11 43.2 0.1 1.1e-10 41.1 0.1 2.3 1 0 0 1 1 1 1 FATC domain Cullin PF00888.22 KXH27123.1 - 3.6e-178 594.0 2.3 4.7e-178 593.7 2.3 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KXH27123.1 - 1.3e-24 86.0 1.4 5.2e-24 84.1 0.3 2.5 2 0 0 2 2 2 1 Cullin protein neddylation domain HbrB PF08539.11 KXH27123.1 - 0.049 13.6 0.1 0.19 11.7 0.1 2.0 1 0 0 1 1 1 0 HbrB-like RL10P_insert PF17777.1 KXH27124.1 - 4.4e-23 81.1 0.0 7.5e-23 80.3 0.0 1.4 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 KXH27124.1 - 1.8e-21 76.1 0.0 2.6e-21 75.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L10 DUF4710 PF15828.5 KXH27124.1 - 0.14 12.3 0.5 0.23 11.6 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4710) U1snRNP70_N PF12220.8 KXH27125.1 - 2.2e-25 89.1 5.2 4.1e-25 88.2 5.2 1.5 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.22 KXH27125.1 - 2.9e-17 62.2 0.1 1.4e-16 60.0 0.1 2.0 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KXH27125.1 - 2.6e-05 24.3 0.0 4.4e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif L51_S25_CI-B8 PF05047.16 KXH27126.1 - 3.5e-17 62.1 0.1 6.5e-17 61.2 0.1 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain TIM PF00121.18 KXH27127.1 - 3.8e-87 291.7 0.6 4.3e-87 291.5 0.6 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase zf-C2H2_4 PF13894.6 KXH27129.1 - 0.0063 17.3 3.1 2.1 9.4 0.9 3.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KXH27129.1 - 0.0065 16.9 3.4 0.2 12.2 0.1 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type Zn_clus PF00172.18 KXH27130.1 - 1.5e-09 37.8 8.0 2.8e-09 36.9 8.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KXH27130.1 - 0.00085 18.2 3.6 0.0018 17.1 1.4 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain FeoB_associated PF12669.7 KXH27130.1 - 5.5 7.5 6.0 17 5.9 6.0 1.9 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein Zn_clus PF00172.18 KXH27132.1 - 0.00046 20.3 12.2 0.0008 19.5 12.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain IMUP PF15761.5 KXH27132.1 - 0.011 16.4 4.5 0.03 15.0 4.5 1.7 1 0 0 1 1 1 0 Immortalisation up-regulated protein MT PF12777.7 KXH27132.1 - 0.043 12.8 0.1 7.3 5.5 0.0 2.3 1 1 1 2 2 2 0 Microtubule-binding stalk of dynein motor MctB PF11382.8 KXH27132.1 - 0.12 12.1 0.1 0.52 10.0 0.0 1.8 2 0 0 2 2 2 0 Copper transport outer membrane protein, MctB SET PF00856.28 KXH27134.1 - 1.6e-11 44.9 0.0 1.9e-10 41.4 0.0 2.7 2 1 0 2 2 2 1 SET domain TPR_2 PF07719.17 KXH27134.1 - 0.0012 18.7 11.1 0.068 13.3 0.1 4.4 5 0 0 5 5 5 2 Tetratricopeptide repeat GLEYA PF10528.9 KXH27134.1 - 0.0046 17.4 0.0 0.011 16.2 0.0 1.6 1 0 0 1 1 1 1 GLEYA domain TPR_16 PF13432.6 KXH27134.1 - 0.008 16.8 1.3 0.008 16.8 1.3 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 KXH27134.1 - 0.05 13.9 7.1 0.15 12.3 0.5 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 KXH27134.1 - 0.25 11.8 1.4 2.2 8.7 0.1 2.6 2 1 0 2 2 2 0 Alkyl sulfatase dimerisation KTI12 PF08433.10 KXH27136.1 - 1.9e-68 230.8 0.0 3.8e-68 229.9 0.0 1.5 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_18 PF13238.6 KXH27136.1 - 0.00074 20.1 0.0 0.0068 16.9 0.0 2.5 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.6 KXH27136.1 - 0.00079 19.6 0.2 0.0023 18.1 0.2 1.8 1 0 0 1 1 1 1 AAA domain CPT PF07931.12 KXH27136.1 - 0.0013 18.6 0.0 0.0026 17.6 0.0 1.4 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_22 PF13401.6 KXH27136.1 - 0.0065 16.7 0.0 0.013 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KXH27136.1 - 0.02 15.3 0.1 0.043 14.2 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain RPOL_N PF14700.6 KXH27136.1 - 0.027 13.9 0.1 0.068 12.6 0.1 1.6 2 0 0 2 2 2 0 DNA-directed RNA polymerase N-terminal AAA_14 PF13173.6 KXH27136.1 - 0.055 13.5 0.0 0.43 10.6 0.0 2.2 1 1 0 1 1 1 0 AAA domain Orthopox_A36R PF05950.11 KXH27136.1 - 0.067 13.4 0.7 0.11 12.7 0.7 1.3 1 0 0 1 1 1 0 Orthopoxvirus A36R protein Oxidored_molyb PF00174.19 KXH27137.1 - 9e-50 168.6 0.0 1.3e-49 168.1 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain SLBB PF10531.9 KXH27137.1 - 0.13 12.1 0.0 1.5 8.7 0.0 2.3 2 0 0 2 2 2 0 SLBB domain Na_Ca_ex PF01699.24 KXH27138.1 - 1.7e-21 76.7 30.2 7e-14 52.0 13.7 3.5 5 0 0 5 5 5 2 Sodium/calcium exchanger protein YccF PF03733.13 KXH27138.1 - 1.1e-16 61.3 11.4 1.1e-16 61.3 11.4 4.2 3 0 0 3 3 3 2 Inner membrane component domain SRR1 PF07985.12 KXH27139.1 - 6.7e-06 26.1 0.2 1.4e-05 25.1 0.2 1.6 1 0 0 1 1 1 1 SRR1 ABC_membrane_2 PF06472.15 KXH27140.1 - 7e-94 314.2 1.8 5.8e-93 311.2 0.1 2.5 3 0 0 3 3 3 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 KXH27140.1 - 1.5e-16 61.1 0.0 4e-16 59.8 0.0 1.7 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 KXH27140.1 - 0.0045 16.8 0.0 0.0096 15.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KXH27140.1 - 0.0052 17.2 0.2 0.016 15.6 0.0 1.9 2 0 0 2 2 1 1 AAA ATPase domain AAA PF00004.29 KXH27140.1 - 0.014 15.8 0.0 0.038 14.4 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) THOC7 PF05615.13 KXH27140.1 - 0.015 15.6 1.1 0.035 14.4 1.1 1.5 1 0 0 1 1 1 0 Tho complex subunit 7 RuvB_N PF05496.12 KXH27140.1 - 0.019 14.7 0.0 0.045 13.5 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain End3 PF12761.7 KXH27140.1 - 0.021 15.0 0.7 0.062 13.5 0.6 1.7 2 0 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 ALIX_LYPXL_bnd PF13949.6 KXH27140.1 - 0.049 12.9 0.1 0.097 11.9 0.1 1.4 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV Mg_chelatase PF01078.21 KXH27140.1 - 0.066 12.6 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 KXH27140.1 - 0.09 12.5 0.0 1.7 8.3 0.0 2.6 2 0 0 2 2 2 0 IstB-like ATP binding protein Sigma54_activat PF00158.26 KXH27140.1 - 0.15 11.7 0.0 0.32 10.7 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_7 PF12775.7 KXH27140.1 - 0.21 11.1 0.0 0.43 10.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_23 PF13476.6 KXH27140.1 - 0.22 12.0 9.5 5.2 7.5 9.5 2.5 1 1 0 1 1 1 0 AAA domain bZIP_2 PF07716.15 KXH27140.1 - 3.7 7.7 12.4 1.3 9.2 2.3 3.1 3 0 0 3 3 3 0 Basic region leucine zipper G6B PF15096.6 KXH27141.1 - 0.0051 16.6 0.0 0.0093 15.8 0.0 1.4 1 0 0 1 1 1 1 G6B family MacB_PCD PF12704.7 KXH27141.1 - 0.12 12.7 0.2 0.21 12.0 0.2 1.4 1 1 0 1 1 1 0 MacB-like periplasmic core domain Pkinase PF00069.25 KXH27142.1 - 1.3e-12 47.7 0.0 6.2e-06 25.8 0.0 3.1 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 KXH27142.1 - 5.4e-11 42.3 0.0 8.7e-08 31.7 0.0 3.0 2 1 0 2 2 2 2 Protein tyrosine kinase Aldo_ket_red PF00248.21 KXH27143.1 - 8.9e-41 140.0 0.0 1.1e-40 139.7 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family LRR_4 PF12799.7 KXH27144.1 - 5.6e-43 144.2 48.8 6.1e-07 29.7 0.2 6.9 1 1 10 11 11 11 11 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXH27144.1 - 2.7e-23 81.5 22.1 1.9e-07 30.7 1.6 5.3 2 2 2 5 5 5 5 Leucine rich repeat LRR_9 PF14580.6 KXH27144.1 - 3.7e-15 55.8 8.0 4.5e-10 39.3 1.8 3.5 1 1 3 4 4 4 4 Leucine-rich repeat LRR_6 PF13516.6 KXH27144.1 - 7.6e-06 25.6 14.9 0.37 11.0 0.3 8.4 10 0 0 10 10 10 2 Leucine Rich repeat LRR_1 PF00560.33 KXH27144.1 - 6.4e-05 23.0 14.0 18 6.4 0.3 8.6 9 2 0 9 9 9 2 Leucine Rich Repeat Abhydrolase_6 PF12697.7 KXH27145.1 - 1.2e-05 26.0 0.5 1.2e-05 26.0 0.5 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXH27145.1 - 0.00056 19.2 0.0 0.022 14.0 0.0 2.2 1 1 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 KXH27145.1 - 0.00057 19.8 0.0 0.0012 18.7 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 KXH27145.1 - 0.004 16.8 0.0 0.037 13.7 0.0 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold BTB PF00651.31 KXH27146.1 - 1.7e-06 28.2 0.0 6.4e-06 26.4 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain PCI PF01399.27 KXH27147.1 - 8.5e-11 42.3 0.0 2.7e-10 40.7 0.0 1.9 2 0 0 2 2 2 1 PCI domain DUF3387 PF11867.8 KXH27147.1 - 0.13 11.6 0.2 5.4 6.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3387) Ribosomal_L18A PF01775.17 KXH27148.1 - 3.3e-54 182.1 0.3 4.1e-54 181.8 0.3 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A DUF4988 PF16378.5 KXH27148.1 - 0.15 11.7 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function Fungal_trans PF04082.18 KXH27149.1 - 3.2e-20 72.3 0.0 5.2e-20 71.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH27149.1 - 4.4e-08 33.1 15.2 6.6e-08 32.6 15.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RNA_pol_3_Rpc31 PF11705.8 KXH27149.1 - 0.01 16.1 4.1 0.045 14.0 4.3 1.9 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Cytomega_UL84 PF06284.11 KXH27149.1 - 0.74 8.2 3.1 1.1 7.6 3.1 1.2 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein GP67 PF17634.2 KXH27149.1 - 1.2 9.6 12.2 3.9 8.0 12.2 1.8 1 0 0 1 1 1 0 Gene product 67 Clusterin PF01093.17 KXH27149.1 - 3.5 6.6 5.8 5.8 5.8 5.8 1.2 1 0 0 1 1 1 0 Clusterin CENP-B_dimeris PF09026.10 KXH27149.1 - 6.5 7.2 19.9 0.75 10.2 13.0 2.7 3 0 0 3 3 3 0 Centromere protein B dimerisation domain SDA1 PF05285.12 KXH27149.1 - 9.8 5.5 8.2 1.1 8.6 2.4 1.9 2 0 0 2 2 2 0 SDA1 Acetyltransf_3 PF13302.7 KXH27150.1 - 1.3e-32 113.4 0.0 1.8e-32 112.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXH27150.1 - 0.055 13.4 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein DUF1772 PF08592.11 KXH27151.1 - 6.2e-30 104.3 7.8 8.2e-30 103.9 7.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) Phage_holin_3_1 PF05106.12 KXH27151.1 - 0.36 11.3 4.5 0.26 11.7 1.1 2.4 1 1 1 2 2 2 0 Phage holin family (Lysis protein S) MFS_1 PF07690.16 KXH27154.1 - 8.9e-37 126.8 71.0 2.6e-35 122.0 71.0 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KXH27154.1 - 3.5e-12 45.6 33.8 6.8e-12 44.6 33.8 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KXH27154.1 - 5e-10 38.8 16.6 5e-10 38.8 16.6 2.9 2 1 1 3 3 3 2 Sugar (and other) transporter Fungal_trans_2 PF11951.8 KXH27155.1 - 6.3e-07 28.5 0.0 1e-05 24.6 0.0 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH27155.1 - 1.3e-06 28.4 10.2 2.8e-06 27.4 10.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_25 PF13649.6 KXH27156.1 - 2.9e-14 53.5 0.0 5.2e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH27156.1 - 4.4e-12 46.5 0.0 7e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXH27156.1 - 5.5e-12 45.8 0.0 7.6e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH27156.1 - 2.5e-07 31.3 0.0 4.8e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH27156.1 - 2.1e-06 27.6 0.0 6e-06 26.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.16 KXH27156.1 - 0.0015 17.2 0.0 0.0019 16.8 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Ubie_methyltran PF01209.18 KXH27156.1 - 0.0026 17.1 0.0 0.0052 16.1 0.0 1.3 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 KXH27156.1 - 0.01 15.3 0.0 0.026 14.0 0.0 1.6 2 0 0 2 2 2 0 Putative methyltransferase UPF0146 PF03686.13 KXH27156.1 - 0.16 11.8 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) Methyltransf_8 PF05148.15 KXH27156.1 - 0.19 11.6 0.0 0.32 10.8 0.0 1.3 1 0 0 1 1 1 0 Hypothetical methyltransferase AglB_L1 PF18079.1 KXH27191.1 - 0.15 12.4 0.0 0.2 12.0 0.0 1.2 1 0 0 1 1 1 0 Archaeal glycosylation protein B long peripheral domain PAS_3 PF08447.12 KXH27193.1 - 1.9e-16 60.1 0.0 2.1e-12 47.1 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 KXH27193.1 - 3.8e-10 39.9 0.0 5.7e-07 29.7 0.0 2.8 3 0 0 3 3 3 2 PAS domain PAS PF00989.25 KXH27193.1 - 5.6e-07 29.5 0.0 0.0006 19.8 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS_11 PF14598.6 KXH27193.1 - 2e-05 24.7 0.0 6.3e-05 23.1 0.0 1.8 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.10 KXH27193.1 - 0.00052 20.2 0.0 0.074 13.3 0.0 2.7 2 0 0 2 2 2 1 PAS fold YL1 PF05764.13 KXH27193.1 - 0.13 12.3 1.8 0.25 11.4 1.8 1.4 1 0 0 1 1 1 0 YL1 nuclear protein Med13_C PF06333.12 KXH27193.1 - 0.38 10.0 0.0 0.38 10.0 0.0 2.7 3 0 0 3 3 3 0 Mediator complex subunit 13 C-terminal domain SDA1 PF05285.12 KXH27193.1 - 4.3 6.7 5.9 6.6 6.0 5.9 1.2 1 0 0 1 1 1 0 SDA1 WD40 PF00400.32 KXH27194.1 - 7.5e-13 48.8 17.9 1.2e-05 25.9 0.6 6.2 7 0 0 7 7 7 4 WD domain, G-beta repeat RNA_pol_I_TF PF04090.12 KXH27195.1 - 0.00014 21.5 0.0 0.05 13.1 0.0 2.2 2 0 0 2 2 2 2 RNA polymerase I specific initiation factor ETC_C1_NDUFA5 PF04716.14 KXH27196.1 - 1.2e-25 89.1 1.8 4.5e-24 84.0 0.2 2.5 2 0 0 2 2 2 2 ETC complex I subunit conserved region Phage_TAC_11 PF11836.8 KXH27196.1 - 0.11 12.6 0.0 0.3 11.2 0.0 1.7 1 0 0 1 1 1 0 Phage tail tube protein, GTA-gp10 BAR_2 PF10455.9 KXH27197.1 - 8.1e-59 199.1 0.0 1.1e-58 198.6 0.0 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 KXH27197.1 - 4e-23 82.3 1.4 1e-21 77.7 1.4 2.0 1 1 0 1 1 1 1 BAR domain BAR_3 PF16746.5 KXH27197.1 - 0.00074 19.3 0.2 0.0067 16.2 0.0 2.4 2 1 0 2 2 2 1 BAR domain of APPL family YdjC PF04794.12 KXH27197.1 - 0.065 13.2 0.4 0.12 12.4 0.4 1.6 1 1 0 1 1 1 0 YdjC-like protein ATP-synt_C PF00137.21 KXH27255.1 - 2e-10 40.8 12.5 2e-10 40.8 12.5 1.7 2 0 0 2 2 2 1 ATP synthase subunit C HET PF06985.11 KXH27257.1 - 5.2e-29 101.5 0.0 1.2e-28 100.4 0.0 1.6 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.7 KXH27258.1 - 1.2e-19 70.6 0.1 5.8e-09 36.4 0.0 4.1 2 2 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXH27258.1 - 1.2e-16 60.9 2.4 2.2e-06 28.1 0.1 5.2 2 2 4 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.30 KXH27258.1 - 2.5e-13 49.8 4.6 0.00057 20.2 0.0 5.5 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 KXH27258.1 - 5.1e-12 45.8 1.1 0.0022 18.3 0.1 4.7 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXH27258.1 - 6e-10 38.5 0.1 0.00026 21.2 0.0 5.7 5 0 0 5 5 5 1 Ankyrin repeat TPR_8 PF13181.6 KXH27258.1 - 7e-05 22.7 0.0 0.00026 21.0 0.0 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.6 KXH27258.1 - 0.00059 20.1 0.5 0.002 18.4 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 KXH27258.1 - 0.0026 18.2 2.6 0.0073 16.8 0.3 3.0 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KXH27258.1 - 0.0027 18.4 1.5 0.12 13.3 0.0 3.7 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 KXH27258.1 - 0.0038 17.2 0.3 0.013 15.5 0.1 2.1 2 0 0 2 2 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 KXH27258.1 - 0.0079 16.0 0.3 0.061 13.2 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat DUF2656 PF10847.8 KXH27258.1 - 0.016 15.3 0.1 0.057 13.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2656) TPR_7 PF13176.6 KXH27258.1 - 0.018 15.1 0.0 0.079 13.0 0.0 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat SesA PF17107.5 KXH27258.1 - 0.021 15.0 0.2 0.074 13.2 0.0 2.0 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases RPN7 PF10602.9 KXH27258.1 - 0.051 13.3 0.1 0.34 10.6 0.1 2.3 2 0 0 2 2 2 0 26S proteasome subunit RPN7 Helo_like_N PF17111.5 KXH27258.1 - 0.068 12.5 0.0 0.18 11.1 0.0 1.8 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins Sugar_tr PF00083.24 KXH27259.1 - 5.1e-79 266.2 7.6 7.1e-79 265.8 7.6 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH27259.1 - 4.9e-13 48.7 36.0 5.7e-07 28.8 14.9 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily PMT_4TMC PF16192.5 KXH27259.1 - 0.27 10.8 2.9 0.21 11.2 0.3 2.1 2 0 0 2 2 2 0 C-terminal four TMM region of protein-O-mannosyltransferase Glyco_hydro_5_C PF18564.1 KXH27260.1 - 1e-22 80.5 0.0 2.5e-22 79.2 0.0 1.7 2 0 0 2 2 2 1 Glycoside hydrolase family 5 C-terminal domain Cellulase PF00150.18 KXH27260.1 - 1.2e-11 44.6 2.9 4e-09 36.3 1.2 2.5 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_35 PF01301.19 KXH27260.1 - 0.029 14.0 0.2 0.053 13.1 0.2 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.15 KXH27260.1 - 0.036 13.4 0.2 0.32 10.3 0.0 2.2 2 0 0 2 2 2 0 Beta-galactosidase Pkinase PF00069.25 KXH27261.1 - 1.5e-63 214.6 0.0 2.2e-63 214.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXH27261.1 - 2.3e-47 161.5 0.0 3.6e-47 160.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXH27261.1 - 4.2e-08 32.9 0.0 2e-06 27.4 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KXH27261.1 - 0.0042 16.5 0.0 0.0091 15.4 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KXH27261.1 - 0.0075 15.1 0.0 0.02 13.7 0.0 1.7 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KXH27261.1 - 0.045 13.7 0.0 0.089 12.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 KXH27261.1 - 0.083 12.5 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 TPR_2 PF07719.17 KXH27262.1 - 1.7e-28 96.4 31.8 0.00022 21.1 0.0 15.6 17 0 0 17 17 16 7 Tetratricopeptide repeat TPR_16 PF13432.6 KXH27262.1 - 9.4e-28 96.6 30.1 4.7e-05 24.0 0.2 12.3 10 3 3 13 13 12 8 Tetratricopeptide repeat TPR_19 PF14559.6 KXH27262.1 - 1.3e-26 92.9 17.7 0.00012 22.5 0.0 11.2 8 4 3 11 11 11 5 Tetratricopeptide repeat TPR_14 PF13428.6 KXH27262.1 - 1.6e-26 90.7 23.3 0.0017 19.0 0.0 15.9 10 6 6 16 16 15 4 Tetratricopeptide repeat TPR_1 PF00515.28 KXH27262.1 - 3.2e-26 90.0 28.3 5.1e-06 26.1 0.0 13.8 14 0 0 14 14 12 6 Tetratricopeptide repeat TPR_17 PF13431.6 KXH27262.1 - 6.9e-22 76.2 10.0 0.62 10.6 0.0 13.8 15 0 0 15 15 12 4 Tetratricopeptide repeat TPR_12 PF13424.6 KXH27262.1 - 1e-15 57.7 33.9 0.02 15.1 0.0 13.3 10 4 3 13 13 13 4 Tetratricopeptide repeat TPR_8 PF13181.6 KXH27262.1 - 3e-15 55.1 26.8 0.0075 16.4 0.0 13.7 14 0 0 14 14 14 2 Tetratricopeptide repeat TPR_11 PF13414.6 KXH27262.1 - 5.1e-15 54.9 19.7 0.016 14.9 0.0 11.3 12 1 1 13 13 12 3 TPR repeat TPR_6 PF13174.6 KXH27262.1 - 3.2e-11 43.1 16.1 0.5 11.1 0.0 13.8 17 0 0 17 17 14 2 Tetratricopeptide repeat TPR_7 PF13176.6 KXH27262.1 - 2.7e-09 36.4 20.5 0.0032 17.4 0.0 10.7 12 1 0 12 12 11 2 Tetratricopeptide repeat TPR_9 PF13371.6 KXH27262.1 - 1e-07 32.0 6.1 0.25 11.5 0.1 6.6 6 1 0 6 6 5 2 Tetratricopeptide repeat TPR_22 PF18833.1 KXH27262.1 - 1e-07 31.9 0.0 3.8e-07 30.2 0.0 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KXH27262.1 - 1.4e-07 31.6 16.8 1.7 8.9 0.0 9.2 9 1 0 10 10 9 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.6 KXH27262.1 - 0.00093 19.5 10.2 4.6 7.6 0.1 6.2 5 0 0 5 5 5 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KXH27262.1 - 0.0033 17.5 0.1 2.2 8.4 0.0 4.8 6 0 0 6 6 5 1 Fis1 C-terminal tetratricopeptide repeat DUF5588 PF17826.1 KXH27262.1 - 0.015 14.3 0.8 0.2 10.5 0.0 3.0 3 0 0 3 3 3 0 Family of unknown function (DUF5588) Coatomer_WDAD PF04053.14 KXH27262.1 - 0.018 14.1 0.0 0.04 13.0 0.0 1.5 1 0 0 1 1 1 0 Coatomer WD associated region RPN6_N PF18055.1 KXH27262.1 - 0.018 15.4 0.1 0.29 11.5 0.1 3.2 2 0 0 2 2 1 0 26S proteasome regulatory subunit RPN6 N-terminal domain NRBF2_MIT PF17169.4 KXH27262.1 - 0.055 13.7 1.8 0.43 10.8 0.4 3.3 2 0 0 2 2 2 0 MIT domain of nuclear receptor-binding factor 2 ChAPs PF09295.10 KXH27262.1 - 0.059 12.4 1.4 12 4.8 0.1 3.8 5 0 0 5 5 5 0 ChAPs (Chs5p-Arf1p-binding proteins) PPTA PF01239.22 KXH27262.1 - 0.061 13.1 0.1 15 5.5 0.0 3.3 3 0 0 3 3 3 0 Protein prenyltransferase alpha subunit repeat DUF4919 PF16266.5 KXH27262.1 - 0.095 12.6 0.4 3.9 7.4 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4919) HemY_N PF07219.13 KXH27262.1 - 0.18 12.0 10.4 20 5.4 0.0 5.6 5 1 1 6 6 5 0 HemY protein N-terminus TPR_10 PF13374.6 KXH27262.1 - 3.1 7.8 16.9 6.5 6.8 0.0 7.3 8 0 0 8 8 7 0 Tetratricopeptide repeat RMI1_N PF08585.12 KXH27263.1 - 7e-54 182.9 0.0 8e-54 182.7 0.0 1.0 1 0 0 1 1 1 1 RecQ mediated genome instability protein Vps51 PF08700.11 KXH27264.1 - 1.5e-27 95.5 0.1 5e-26 90.6 0.1 2.4 1 1 0 1 1 1 1 Vps51/Vps67 COG5 PF10392.9 KXH27264.1 - 5.4e-06 26.6 0.0 8.3e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Golgi transport complex subunit 5 Dor1 PF04124.12 KXH27264.1 - 3.2e-05 22.8 0.0 4.4e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 Dor1-like family FlgN PF05130.12 KXH27264.1 - 0.19 12.3 0.2 0.94 10.0 0.1 2.0 1 1 1 2 2 2 0 FlgN protein NIF3 PF01784.18 KXH27265.1 - 2e-59 201.2 0.0 2.4e-59 200.9 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) AdoMet_dc PF02675.15 KXH27265.1 - 0.046 14.0 0.1 0.1 12.8 0.1 1.6 1 0 0 1 1 1 0 S-adenosylmethionine decarboxylase Peripla_BP_6 PF13458.6 KXH27265.1 - 0.061 13.0 0.7 0.11 12.1 0.3 1.7 2 0 0 2 2 2 0 Periplasmic binding protein Glyco_hydro_43 PF04616.14 KXH27432.1 - 4.6e-38 131.2 8.2 5.2e-38 131.0 8.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Cu-oxidase_3 PF07732.15 KXH27434.1 - 1.1e-36 125.4 0.4 6.3e-36 123.0 0.5 2.1 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KXH27434.1 - 2.5e-22 79.1 7.8 4.8e-18 65.2 0.5 3.5 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 KXH27434.1 - 9.4e-07 29.1 0.1 3e-06 27.5 0.0 1.9 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 KXH27435.1 - 6.7e-22 77.7 0.5 9.6e-21 74.0 0.2 2.4 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.22 KXH27435.1 - 1e-17 64.7 0.0 1.7e-17 64.0 0.0 1.3 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KXH27435.1 - 4.3e-09 36.2 0.0 5e-06 26.3 0.0 2.5 2 0 0 2 2 2 2 Multicopper oxidase Sensor_TM1 PF13755.6 KXH27438.1 - 0.2 11.4 2.0 0.3 10.9 0.3 2.0 2 0 0 2 2 2 0 Sensor N-terminal transmembrane domain Glyco_hydro_76 PF03663.14 KXH27439.1 - 2.5e-143 478.0 12.7 2.9e-143 477.8 12.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 FAD_binding_3 PF01494.19 KXH27441.1 - 3.7e-19 69.2 1.2 3.5e-11 43.0 0.4 2.8 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KXH27441.1 - 5.7e-07 29.7 0.0 1.4e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXH27441.1 - 5e-06 26.0 0.1 0.0028 16.9 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXH27441.1 - 0.00023 20.8 0.0 0.00044 20.0 0.0 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KXH27441.1 - 0.001 18.3 0.5 0.0018 17.4 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KXH27441.1 - 0.0011 17.8 0.0 0.0015 17.3 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein Amino_oxidase PF01593.24 KXH27441.1 - 0.0014 18.0 0.1 0.13 11.5 0.0 2.4 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase IlvN PF07991.12 KXH27441.1 - 0.0022 17.6 0.0 0.0044 16.6 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain Pyr_redox PF00070.27 KXH27441.1 - 0.004 17.7 0.0 0.0099 16.4 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 KXH27441.1 - 0.007 16.3 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.17 KXH27441.1 - 0.012 14.9 0.0 0.022 14.0 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.12 KXH27441.1 - 0.022 13.8 0.4 0.11 11.5 0.1 2.2 3 0 0 3 3 3 0 Lycopene cyclase protein TrkA_N PF02254.18 KXH27441.1 - 0.022 15.0 0.0 0.048 13.9 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain AlaDh_PNT_C PF01262.21 KXH27441.1 - 0.027 13.8 0.0 0.051 12.9 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 KXH27441.1 - 0.031 13.3 0.0 0.046 12.8 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 KXH27441.1 - 0.035 13.3 0.0 0.065 12.5 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 KXH27441.1 - 0.098 12.2 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FMO-like PF00743.19 KXH27441.1 - 0.15 10.4 0.0 0.22 9.9 0.0 1.1 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like Shikimate_DH PF01488.20 KXH27441.1 - 0.17 12.0 0.0 0.31 11.1 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Zn_clus PF00172.18 KXH27443.1 - 9.6e-06 25.6 8.9 1.8e-05 24.8 8.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4449 PF14613.6 KXH27443.1 - 0.089 12.9 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4449) SMBP PF16785.5 KXH27443.1 - 0.14 12.4 0.2 0.6 10.4 0.2 2.0 1 1 0 1 1 1 0 Small metal-binding protein Mito_carr PF00153.27 KXH27444.1 - 1.1e-46 156.6 4.7 3.3e-15 55.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein MFS_1 PF07690.16 KXH27446.1 - 2.3e-35 122.2 27.7 2.3e-35 122.2 27.7 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 KXH27446.1 - 0.0036 17.0 1.6 0.011 15.5 1.6 1.8 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 CoA_trans PF01144.23 KXH27447.1 - 1.7e-100 334.9 4.0 7.3e-59 198.8 0.3 2.0 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.6 KXH27447.1 - 0.00013 22.0 0.2 0.00031 20.7 0.2 1.6 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain Mal_decarbox_Al PF16957.5 KXH27447.1 - 0.035 12.4 1.0 0.042 12.2 0.2 1.4 2 0 0 2 2 2 0 Malonate decarboxylase, alpha subunit, transporter Catalase PF00199.19 KXH27449.1 - 3.6e-08 32.9 0.0 6.6e-07 28.8 0.0 2.1 1 1 0 1 1 1 1 Catalase NUDIX PF00293.28 KXH27450.1 - 0.0001 22.4 0.0 0.0002 21.4 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain Thiolase_N PF00108.23 KXH27451.1 - 9.7e-70 234.9 1.3 1.3e-69 234.5 1.3 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KXH27451.1 - 1.3e-39 134.6 1.6 2.4e-39 133.8 0.5 1.9 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KXH27451.1 - 0.0087 15.7 0.4 0.035 13.7 0.1 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ank_2 PF12796.7 KXH27452.1 - 9.5e-30 103.0 0.0 1.5e-10 41.5 0.0 3.8 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXH27452.1 - 5e-21 72.5 3.3 0.00077 19.7 0.1 7.9 8 0 0 8 8 8 5 Ankyrin repeat Ank_4 PF13637.6 KXH27452.1 - 2.4e-20 72.6 3.9 8e-06 26.3 0.1 6.9 2 2 6 8 8 8 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXH27452.1 - 1.2e-19 70.1 7.0 1.6e-07 31.5 0.3 6.9 5 2 2 7 7 7 4 Ankyrin repeats (many copies) Ank PF00023.30 KXH27452.1 - 2.2e-18 65.8 8.1 5.9e-06 26.5 0.5 7.3 7 0 0 7 7 7 3 Ankyrin repeat MFS_1 PF07690.16 KXH27453.1 - 7.8e-38 130.3 17.6 7.8e-38 130.3 17.6 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily ABC2_membrane PF01061.24 KXH27454.1 - 6.3e-94 313.3 55.2 1.6e-49 168.2 20.0 3.4 4 0 0 4 4 3 2 ABC-2 type transporter ABC_tran PF00005.27 KXH27454.1 - 2.3e-35 122.1 0.0 2.9e-16 60.2 0.0 3.3 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.12 KXH27454.1 - 2.6e-34 117.0 12.3 7.2e-32 109.2 0.0 3.6 4 0 0 4 4 3 2 CDR ABC transporter ABC_trans_N PF14510.6 KXH27454.1 - 1.5e-18 67.2 0.1 6.9e-18 65.0 0.1 2.2 2 0 0 2 2 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 KXH27454.1 - 1.8e-06 28.5 0.5 0.00095 19.6 0.1 2.8 3 0 0 3 3 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 KXH27454.1 - 2.8e-06 27.3 0.1 0.00035 20.5 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 KXH27454.1 - 9.9e-06 25.3 0.1 0.00081 19.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 KXH27454.1 - 4.1e-05 23.6 0.0 1.2 8.9 0.0 3.5 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KXH27454.1 - 0.00029 20.5 0.9 0.035 13.8 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.6 KXH27454.1 - 0.0004 20.9 0.0 0.075 13.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KXH27454.1 - 0.0006 20.0 0.1 0.19 11.9 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KXH27454.1 - 0.0032 17.7 0.3 0.82 9.9 0.1 2.8 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 KXH27454.1 - 0.0051 16.4 0.6 0.11 12.1 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain SMC_N PF02463.19 KXH27454.1 - 0.0051 16.3 0.0 2.1 7.7 0.0 3.5 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain NACHT PF05729.12 KXH27454.1 - 0.0093 15.9 0.0 1.7 8.5 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_17 PF13207.6 KXH27454.1 - 0.032 14.7 0.5 5.6 7.4 0.0 3.0 2 1 0 2 2 2 0 AAA domain AAA_23 PF13476.6 KXH27454.1 - 0.051 14.1 0.2 0.23 11.9 0.1 2.0 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KXH27454.1 - 0.062 13.0 0.1 6.2 6.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KXH27454.1 - 0.11 12.8 0.1 1.1 9.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KXH27454.1 - 0.12 12.8 0.1 16 5.9 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KXH27454.1 - 0.16 11.7 1.0 12 5.6 0.1 2.3 2 0 0 2 2 2 0 AAA domain ECF-ribofla_trS PF07155.12 KXH27454.1 - 0.82 9.7 11.2 0.13 12.3 0.2 3.3 3 0 0 3 3 3 0 ECF-type riboflavin transporter, S component VEK-30 PF12107.8 KXH27454.1 - 1 9.3 3.1 0.35 10.8 0.1 1.8 2 0 0 2 2 1 0 Plasminogen (Pg) ligand in fibrinolytic pathway Voltage_CLC PF00654.20 KXH27454.1 - 2.6 7.2 16.5 0.23 10.7 2.7 3.1 3 0 0 3 3 3 0 Voltage gated chloride channel ABC2_membrane_3 PF12698.7 KXH27454.1 - 4.7 6.2 50.7 11 5.0 0.1 4.0 3 2 0 3 3 3 0 ABC-2 family transporter protein NmrA PF05368.13 KXH27456.1 - 2.1e-27 96.2 0.3 2.7e-27 95.9 0.3 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXH27456.1 - 2.8e-20 73.0 1.7 3e-19 69.6 0.2 2.2 1 1 1 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 KXH27456.1 - 1.3e-05 24.8 0.3 8.2e-05 22.2 0.1 2.4 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 KXH27456.1 - 5.3e-05 23.3 0.3 0.00012 22.2 0.3 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 3Beta_HSD PF01073.19 KXH27456.1 - 0.00071 18.7 0.1 0.0016 17.5 0.1 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 KXH27456.1 - 0.0087 15.5 0.5 0.017 14.6 0.5 1.4 1 0 0 1 1 1 1 short chain dehydrogenase 2-oxoacid_dh PF00198.23 KXH27456.1 - 0.01 15.3 1.1 0.019 14.4 0.3 1.8 2 0 0 2 2 2 0 2-oxoacid dehydrogenases acyltransferase (catalytic domain) NAD_binding_2 PF03446.15 KXH27456.1 - 0.021 15.0 0.4 0.07 13.3 0.2 1.9 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Adeno_PV PF03910.13 KXH27456.1 - 0.031 13.0 1.4 0.048 12.4 1.0 1.4 2 0 0 2 2 2 0 Adenovirus minor core protein PV Fungal_trans_2 PF11951.8 KXH27457.1 - 2.3e-31 109.0 1.4 3.4e-31 108.4 1.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH27457.1 - 3.2e-06 27.2 10.8 5.3e-06 26.5 10.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NmrA PF05368.13 KXH27458.1 - 1.7e-29 103.1 0.0 2.4e-29 102.6 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXH27458.1 - 1.2e-21 77.5 0.0 1.8e-21 76.9 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KXH27458.1 - 0.097 12.9 0.0 0.26 11.5 0.0 1.7 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Glyco_hydro_92 PF07971.12 KXH27459.1 - 1.9e-143 478.7 0.1 2.4e-143 478.4 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 KXH27459.1 - 1.2e-52 179.2 1.5 2.1e-52 178.4 1.5 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain p450 PF00067.22 KXH27460.1 - 2.5e-76 257.3 0.0 3.2e-76 256.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_3 PF01494.19 KXH27461.1 - 1.9e-19 70.2 0.0 3.6e-19 69.2 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KXH27461.1 - 1.3e-10 41.0 0.6 5e-07 29.2 0.3 2.2 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXH27461.1 - 1.6e-09 37.9 0.4 8.1e-07 28.9 0.4 2.5 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXH27461.1 - 3.3e-08 33.6 0.3 8e-08 32.4 0.3 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KXH27461.1 - 3.6e-07 29.6 1.5 6.2e-07 28.8 1.5 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KXH27461.1 - 7.5e-06 24.9 0.2 1.6e-05 23.8 0.2 1.6 1 1 0 1 1 1 1 HI0933-like protein Amino_oxidase PF01593.24 KXH27461.1 - 1.5e-05 24.5 0.2 0.008 15.5 0.1 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 KXH27461.1 - 5e-05 22.8 0.8 7.7e-05 22.2 0.8 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KXH27461.1 - 0.0001 21.3 0.1 0.0022 16.9 0.3 2.1 2 0 0 2 2 2 1 Tryptophan halogenase GIDA PF01134.22 KXH27461.1 - 0.00012 21.3 2.1 0.00018 20.7 2.1 1.4 1 1 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.27 KXH27461.1 - 0.00074 20.0 0.5 0.0023 18.4 0.5 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KXH27461.1 - 0.0011 18.0 0.0 0.4 9.7 0.1 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein SE PF08491.10 KXH27461.1 - 0.0017 17.4 0.0 0.0064 15.6 0.0 1.8 2 0 0 2 2 2 1 Squalene epoxidase Pyr_redox_3 PF13738.6 KXH27461.1 - 0.002 17.5 0.9 0.002 17.5 0.9 1.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KXH27461.1 - 0.0041 16.4 1.8 0.0061 15.9 0.5 1.8 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.6 KXH27461.1 - 0.0084 16.1 0.4 1.9 8.5 0.2 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding ApbA PF02558.16 KXH27461.1 - 0.042 13.5 0.7 0.18 11.4 0.7 1.9 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Thi4 PF01946.17 KXH27461.1 - 0.064 12.5 0.3 0.11 11.7 0.3 1.4 1 0 0 1 1 1 0 Thi4 family NAD_binding_2 PF03446.15 KXH27461.1 - 0.15 12.3 0.3 0.6 10.3 0.0 1.9 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 KXH27461.1 - 0.16 11.9 0.7 0.25 11.2 0.2 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 KXH27461.1 - 0.18 11.8 0.2 0.35 10.8 0.2 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Sec8_exocyst PF04048.14 KXH27462.1 - 0.067 13.1 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain SF3b1 PF08920.10 KXH27480.1 - 4.4e-28 98.2 7.5 4.4e-28 98.2 7.5 2.4 1 1 1 2 2 2 1 Splicing factor 3B subunit 1 HEAT_EZ PF13513.6 KXH27480.1 - 4.6e-12 46.2 2.0 0.015 15.8 0.0 7.6 7 1 1 8 8 8 2 HEAT-like repeat HEAT_2 PF13646.6 KXH27480.1 - 3.2e-10 40.2 8.5 0.1 13.0 0.1 7.8 5 3 3 9 9 9 3 HEAT repeats HEAT PF02985.22 KXH27480.1 - 3.3e-09 36.2 8.1 0.74 10.2 0.0 9.0 9 0 0 9 9 9 2 HEAT repeat Cnd1 PF12717.7 KXH27480.1 - 5e-06 26.6 0.6 2.3 8.3 0.0 6.1 5 2 2 7 7 7 1 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 KXH27480.1 - 8.7e-05 23.0 0.2 1.2 9.8 0.0 5.2 6 0 0 6 6 6 1 Vacuolar 14 Fab1-binding region DUF3385 PF11865.8 KXH27480.1 - 0.00015 21.7 0.5 0.016 15.1 0.0 4.2 5 1 0 5 5 5 1 Domain of unknown function (DUF3385) NUC173 PF08161.12 KXH27480.1 - 0.0002 21.1 0.9 0.95 9.1 0.0 4.2 5 1 0 5 5 5 2 NUC173 domain Adaptin_N PF01602.20 KXH27480.1 - 0.00052 18.7 0.2 0.21 10.1 0.0 3.2 2 2 0 3 3 3 2 Adaptin N terminal region UME PF08064.13 KXH27480.1 - 0.00082 19.2 0.0 2.4 8.1 0.0 4.5 4 0 0 4 4 4 1 UME (NUC010) domain UNC45-central PF11701.8 KXH27480.1 - 0.0025 17.8 0.0 0.0075 16.2 0.0 1.8 2 0 0 2 2 1 1 Myosin-binding striated muscle assembly central CLASP_N PF12348.8 KXH27480.1 - 0.016 14.8 0.0 1.8 8.0 0.0 3.6 4 0 0 4 4 4 0 CLASP N terminal DRIM PF07539.12 KXH27480.1 - 0.04 12.2 0.2 7 4.8 0.0 3.7 2 1 2 4 4 4 0 Down-regulated in metastasis OGG_N PF07934.12 KXH27481.1 - 7.1e-23 81.0 0.0 1.4e-22 80.1 0.0 1.5 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 KXH27481.1 - 2.3e-17 63.4 0.0 3.8e-17 62.7 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 KXH27481.1 - 0.00018 21.2 0.0 0.00053 19.7 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif LSM PF01423.22 KXH27482.1 - 2e-17 62.6 0.5 2.5e-17 62.3 0.5 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KXH27482.1 - 0.0027 17.8 0.0 0.0033 17.5 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain Hfq PF17209.3 KXH27482.1 - 0.01 15.5 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 0 Hfq protein DUF150_C PF17384.2 KXH27482.1 - 0.074 13.2 0.1 0.11 12.7 0.1 1.3 1 0 0 1 1 1 0 RimP C-terminal SH3 domain DRMBL PF07522.14 KXH27483.1 - 9.9e-35 119.1 0.0 2e-34 118.1 0.0 1.5 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 KXH27483.1 - 2.1e-06 27.4 0.0 4.6e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_6 PF16661.5 KXH27483.1 - 0.21 11.0 0.0 0.36 10.2 0.0 1.3 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily domain HOASN PF14515.6 KXH27484.1 - 0.063 13.7 0.0 0.17 12.3 0.0 1.7 2 0 0 2 2 2 0 Haem-oxygenase-associated N-terminal helices Ank_2 PF12796.7 KXH27485.1 - 1.9e-61 204.6 0.1 1e-13 51.7 0.0 6.3 2 2 4 7 7 7 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXH27485.1 - 5.7e-50 167.1 4.7 9.9e-08 32.4 0.1 10.0 4 2 6 10 10 10 9 Ankyrin repeats (many copies) Ank PF00023.30 KXH27485.1 - 7.9e-45 149.4 12.0 0.00011 22.5 0.0 13.1 12 1 1 13 13 13 9 Ankyrin repeat Ank_5 PF13857.6 KXH27485.1 - 3.2e-42 142.0 9.3 2.2e-07 31.0 0.0 8.9 4 1 6 10 10 10 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXH27485.1 - 4.3e-39 128.1 7.5 0.00017 21.8 0.0 12.1 12 1 0 12 12 11 6 Ankyrin repeat DUF4164 PF13747.6 KXH27485.1 - 0.032 14.5 0.4 0.065 13.5 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) DUF4635 PF15466.6 KXH27485.1 - 0.039 13.5 0.5 0.1 12.1 0.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4635) Aldedh PF00171.22 KXH27485.1 - 0.06 11.8 0.1 0.14 10.6 0.1 1.5 2 0 0 2 2 2 0 Aldehyde dehydrogenase family Syntaxin-6_N PF09177.11 KXH27485.1 - 0.075 13.6 2.2 0.12 13.0 0.5 2.1 2 0 0 2 2 2 0 Syntaxin 6, N-terminal End3 PF12761.7 KXH27485.1 - 0.58 10.3 4.5 1.5 9.0 4.5 1.7 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 DUF948 PF06103.11 KXH27485.1 - 2.4 8.5 5.1 24 5.3 0.1 3.0 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF3602 PF12223.8 KXH27486.1 - 8.6e-24 83.9 17.7 9.1e-23 80.7 4.4 2.8 2 1 1 3 3 3 2 Protein of unknown function (DUF3602) ATG22 PF11700.8 KXH27487.1 - 9e-84 281.8 1.4 1.1e-76 258.4 0.0 2.0 1 1 1 2 2 2 2 Vacuole effluxer Atg22 like LDB19 PF13002.7 KXH27497.1 - 2.7e-34 118.6 0.4 4.5e-34 117.9 0.4 1.2 1 0 0 1 1 1 1 Arrestin_N terminal like Arrestin_N PF00339.29 KXH27497.1 - 3.2e-05 24.0 0.0 8.8e-05 22.6 0.0 1.8 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain TPR_12 PF13424.6 KXH27519.1 - 0.0013 18.9 2.8 0.91 9.9 0.1 3.7 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KXH27519.1 - 0.079 13.1 1.8 73 3.8 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Cwf_Cwc_15 PF04889.12 KXH27519.1 - 0.23 11.2 2.7 0.37 10.5 2.7 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein TPR_1 PF00515.28 KXH27519.1 - 0.93 9.4 2.3 29 4.7 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KXH27519.1 - 3.2 8.0 4.7 5.1 7.4 2.8 2.3 1 1 2 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 IBR PF01485.21 KXH27534.1 - 8.2e-20 70.8 37.9 1.9e-15 56.8 3.9 4.5 4 1 1 5 5 5 3 IBR domain, a half RING-finger domain RWD PF05773.22 KXH27534.1 - 1.3e-15 57.7 0.0 2.6e-15 56.7 0.0 1.5 1 0 0 1 1 1 1 RWD domain zf-RING_2 PF13639.6 KXH27534.1 - 0.0004 20.6 7.6 0.0004 20.6 7.6 4.1 3 1 1 4 4 4 2 Ring finger domain zf-RING_UBOX PF13445.6 KXH27534.1 - 0.00053 19.9 5.9 0.00053 19.9 5.9 3.7 3 0 0 3 3 3 2 RING-type zinc-finger zf-C3HC4 PF00097.25 KXH27534.1 - 0.0093 15.8 8.4 0.0093 15.8 8.4 4.2 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KXH27534.1 - 0.012 15.3 7.4 0.044 13.5 7.4 2.0 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_5 PF14634.6 KXH27534.1 - 0.014 15.4 8.0 0.014 15.4 8.0 4.1 3 1 0 3 3 3 0 zinc-RING finger domain PAP2 PF01569.21 KXH27535.1 - 1.9e-13 50.3 5.2 1.9e-13 50.3 5.2 2.5 1 1 1 2 2 2 1 PAP2 superfamily UbiA PF01040.18 KXH27535.1 - 0.00012 21.5 1.9 0.00012 21.5 1.9 2.0 2 0 0 2 2 2 1 UbiA prenyltransferase family DUF212 PF02681.14 KXH27535.1 - 0.0069 16.5 0.1 0.27 11.4 0.0 2.3 1 1 1 2 2 2 1 Divergent PAP2 family DUF1345 PF07077.11 KXH27535.1 - 0.11 12.2 5.1 0.13 12.0 2.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1345) Fungal_trans PF04082.18 KXH27565.1 - 1.3e-22 80.1 0.0 2.1e-22 79.4 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH27565.1 - 6.9e-08 32.5 13.7 1.5e-07 31.5 13.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tmemb_cc2 PF10267.9 KXH27565.1 - 0.0089 15.2 0.0 0.013 14.7 0.0 1.1 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein Methyltransf_23 PF13489.6 KXH27624.1 - 1.4e-18 67.3 0.0 2.1e-18 66.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH27624.1 - 6.6e-10 39.6 0.0 2.1e-09 37.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH27624.1 - 9.9e-09 35.2 0.0 3.7e-07 30.1 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH27624.1 - 3.4e-08 34.0 0.0 9.7e-08 32.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH27624.1 - 2.4e-06 28.2 0.0 2.1e-05 25.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain CheR PF01739.18 KXH27624.1 - 0.00012 21.7 0.0 0.0024 17.4 0.0 2.1 2 0 0 2 2 2 1 CheR methyltransferase, SAM binding domain MTS PF05175.14 KXH27624.1 - 0.0067 16.0 0.0 0.17 11.4 0.1 2.2 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_4 PF02390.17 KXH27624.1 - 0.014 14.9 0.0 0.092 12.2 0.0 2.1 2 0 0 2 2 2 0 Putative methyltransferase Ubie_methyltran PF01209.18 KXH27624.1 - 0.017 14.5 0.1 11 5.2 0.0 3.0 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family PrmA PF06325.13 KXH27624.1 - 0.026 13.9 0.0 0.05 13.0 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.19 KXH27624.1 - 0.14 12.3 0.0 0.24 11.5 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_23 PF13489.6 KXH27625.1 - 1.5e-10 41.1 0.0 2.3e-05 24.3 0.0 2.2 1 1 1 2 2 2 2 Methyltransferase domain Ubie_methyltran PF01209.18 KXH27625.1 - 0.002 17.5 0.0 0.84 8.9 0.0 2.3 1 1 1 2 2 2 2 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 KXH27625.1 - 0.013 16.1 0.0 0.029 15.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 KXH27625.1 - 0.047 13.5 0.0 0.14 11.9 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain PrmA PF06325.13 KXH27625.1 - 0.072 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 KXH27625.1 - 0.093 13.4 0.0 0.25 12.0 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 KXH27626.1 - 6.6e-23 81.4 0.0 8.3e-23 81.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH27626.1 - 3.4e-09 36.7 0.0 0.0017 18.2 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 KXH27626.1 - 5.3e-09 36.7 0.0 1.6e-08 35.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH27626.1 - 6.2e-08 33.2 0.0 1.8e-07 31.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH27626.1 - 3.1e-05 24.6 0.0 0.00031 21.4 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 KXH27626.1 - 0.0021 18.2 0.0 0.0041 17.3 0.0 1.4 1 1 0 1 1 1 1 FtsJ-like methyltransferase CheR PF01739.18 KXH27626.1 - 0.0051 16.3 0.0 0.012 15.1 0.0 1.6 2 0 0 2 2 2 1 CheR methyltransferase, SAM binding domain Methyltransf_4 PF02390.17 KXH27626.1 - 0.0066 15.9 0.0 0.016 14.7 0.0 1.6 2 0 0 2 2 2 1 Putative methyltransferase Ubie_methyltran PF01209.18 KXH27626.1 - 0.0081 15.5 0.0 2.2 7.5 0.0 2.7 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family PrmA PF06325.13 KXH27626.1 - 0.0089 15.5 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KXH27626.1 - 0.01 15.4 0.0 0.065 12.8 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase small domain Met_10 PF02475.16 KXH27626.1 - 0.15 11.8 0.0 0.23 11.2 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein HET PF06985.11 KXH27627.1 - 9.2e-34 116.9 0.5 1.6e-33 116.1 0.5 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HSF_DNA-bind PF00447.17 KXH27629.1 - 1.2e-29 102.7 0.6 2.1e-29 102.0 0.6 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding PGI PF00342.19 KXH27630.1 - 1.2e-225 749.7 0.7 1.4e-225 749.5 0.7 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase Pkinase PF00069.25 KXH27656.1 - 3.6e-42 144.6 0.0 9.8e-41 139.9 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXH27656.1 - 1.3e-27 96.8 0.0 2e-27 96.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXH27656.1 - 0.0041 16.0 0.0 0.0063 15.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KXH27656.1 - 0.049 13.5 0.1 0.093 12.6 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 KXH27656.1 - 0.091 12.1 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Clr5 PF14420.6 KXH27657.1 - 6.9e-18 64.6 3.3 1.5e-17 63.5 3.3 1.6 1 0 0 1 1 1 1 Clr5 domain TPR_12 PF13424.6 KXH27657.1 - 2.3e-05 24.6 7.2 3e-05 24.2 0.9 3.1 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 KXH27657.1 - 0.028 14.2 0.0 12 5.9 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 KXH27657.1 - 0.034 14.6 1.4 0.37 11.3 0.8 2.9 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 KXH27657.1 - 0.039 14.1 0.1 14 6.1 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat FAD_binding_6 PF00970.24 KXH27657.1 - 0.083 13.2 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain SAP PF02037.27 KXH27659.1 - 1.6e-11 43.6 0.3 2.8e-11 42.9 0.3 1.4 1 0 0 1 1 1 1 SAP domain Tho1_MOS11_C PF18592.1 KXH27659.1 - 3.4e-07 30.0 1.8 3.4e-07 30.0 1.8 2.4 2 0 0 2 2 2 1 Tho1/MOS11 C-terminal domain Mitofilin PF09731.9 KXH27659.1 - 0.031 13.1 22.0 0.039 12.8 22.0 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein HeH PF12949.7 KXH27659.1 - 0.097 12.4 0.3 0.23 11.2 0.3 1.7 1 0 0 1 1 1 0 HeH/LEM domain Metallophos PF00149.28 KXH27660.1 - 1.3e-16 61.7 0.4 2.4e-16 60.8 0.1 1.6 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase GST_N PF02798.20 KXH27662.1 - 1.5e-15 57.3 0.0 2.8e-15 56.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KXH27662.1 - 3e-13 50.0 0.0 5.5e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KXH27662.1 - 4.1e-12 46.2 0.0 9.3e-12 45.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KXH27662.1 - 1.8e-08 34.5 0.0 7.4e-08 32.5 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KXH27662.1 - 2.7e-08 33.9 0.0 5.2e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KXH27662.1 - 3.7e-07 30.1 0.4 2.2e-06 27.6 0.2 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain SF1-HH PF16275.5 KXH27663.1 - 3.3e-41 140.2 5.1 2.3e-40 137.4 0.2 2.4 1 1 1 2 2 2 2 Splicing factor 1 helix-hairpin domain KH_1 PF00013.29 KXH27663.1 - 8.5e-09 35.1 0.3 1.6e-08 34.2 0.3 1.5 1 0 0 1 1 1 1 KH domain PQ-loop PF04193.14 KXH27664.1 - 6.7e-25 86.6 2.2 3.2e-17 62.0 0.2 2.9 2 1 0 2 2 2 2 PQ loop repeat DUF5353 PF17304.2 KXH27664.1 - 0.36 10.6 2.5 1.4 8.7 0.1 2.7 3 0 0 3 3 3 0 Family of unknown function (DUF5353) Peptidase_U4 PF03419.13 KXH27664.1 - 1.1 8.5 10.2 0.78 9.0 7.8 1.8 1 1 1 2 2 2 0 Sporulation factor SpoIIGA AA_permease PF00324.21 KXH27665.1 - 1.7e-118 396.3 44.6 2.1e-118 396.0 44.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KXH27665.1 - 2.3e-31 109.1 47.7 3.1e-31 108.7 47.7 1.1 1 0 0 1 1 1 1 Amino acid permease Fungal_trans PF04082.18 KXH27667.1 - 4.8e-07 29.1 0.1 4.8e-07 29.1 0.1 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Aldo_ket_red PF00248.21 KXH27668.1 - 3.2e-44 151.3 0.0 4e-44 151.0 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Glyco_hydro_3 PF00933.21 KXH27669.1 - 6.1e-47 160.5 0.0 1.1e-46 159.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 KXH27669.1 - 3.7e-42 144.6 0.0 5.5e-42 144.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 KXH27669.1 - 6.6e-20 71.0 0.4 1.4e-19 70.0 0.4 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 KXH27669.1 - 2.5e-06 27.3 0.1 5.4e-06 26.3 0.1 1.5 1 0 0 1 1 1 1 PA14 domain HsbA PF12296.8 KXH27670.1 - 9.5e-26 90.6 3.4 9.5e-26 90.6 3.4 1.6 1 1 0 1 1 1 1 Hydrophobic surface binding protein A HWE_HK PF07536.14 KXH27670.1 - 0.014 16.1 0.1 0.048 14.4 0.0 2.0 2 1 1 3 3 3 0 HWE histidine kinase Carbpep_Y_N PF05388.11 KXH27670.1 - 0.027 15.0 0.1 0.063 13.8 0.1 1.6 1 0 0 1 1 1 0 Carboxypeptidase Y pro-peptide Dynein_C PF18199.1 KXH27670.1 - 0.067 12.4 0.0 0.19 11.0 0.0 1.6 1 1 0 1 1 1 0 Dynein heavy chain C-terminal domain Corona_S2 PF01601.16 KXH27670.1 - 0.21 10.1 4.6 0.47 8.9 4.6 1.6 1 1 0 1 1 1 0 Coronavirus S2 glycoprotein Pheromone PF08015.11 KXH27671.1 - 0.76 10.9 0.1 0.76 10.9 0.1 2.6 4 0 0 4 4 4 0 Fungal mating-type pheromone GTP_cyclohydroI PF01227.22 KXH27672.1 - 7.3e-75 250.3 0.6 9.7e-75 249.9 0.6 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 KXH27672.1 - 0.0022 18.1 0.0 0.0041 17.2 0.0 1.4 1 0 0 1 1 1 1 QueF-like protein Apt1 PF10351.9 KXH27672.1 - 0.56 9.0 7.5 0.66 8.8 7.5 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain TAFII28 PF04719.14 KXH27673.1 - 3.3e-32 110.4 0.0 5.5e-32 109.7 0.0 1.4 1 0 0 1 1 1 1 hTAFII28-like protein conserved region Aa_trans PF01490.18 KXH27674.1 - 1e-31 110.1 26.3 2.5e-31 108.8 26.3 1.4 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein UvdE PF03851.14 KXH27675.1 - 1.4e-113 378.7 0.0 1.9e-113 378.3 0.0 1.2 1 0 0 1 1 1 1 UV-endonuclease UvdE DUF5323 PF17257.2 KXH27675.1 - 1.3 9.0 17.3 1.3 9.0 3.6 3.7 3 0 0 3 3 3 0 Family of unknown function (DUF5323) E1-E2_ATPase PF00122.20 KXH27676.1 - 7e-37 126.7 14.5 9.3e-31 106.7 0.1 3.1 3 0 0 3 3 3 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 KXH27676.1 - 8.5e-24 84.3 12.2 8.5e-24 84.3 12.2 2.4 2 1 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KXH27676.1 - 4.7e-20 72.8 0.0 2.1e-18 67.4 0.0 2.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KXH27676.1 - 7e-16 58.1 0.0 1.6e-15 57.0 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KXH27676.1 - 5.9e-14 51.5 0.0 1.5e-13 50.2 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KXH27676.1 - 0.00041 20.2 0.3 0.0009 19.0 0.2 1.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase ZnuA PF01297.17 KXH27677.1 - 0.038 13.4 0.9 0.073 12.5 0.4 1.6 2 0 0 2 2 2 0 Zinc-uptake complex component A periplasmic DUF572 PF04502.13 KXH27677.1 - 0.31 10.6 6.7 0.5 9.9 6.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) RIFIN PF02009.16 KXH27677.1 - 1.8 8.4 7.3 0.33 10.8 3.9 1.5 2 0 0 2 2 2 0 Rifin Arylesterase PF01731.20 KXH27678.1 - 0.0014 18.7 0.1 0.011 16.0 0.1 2.5 1 1 0 1 1 1 1 Arylesterase Sugar_tr PF00083.24 KXH27679.1 - 1.7e-96 323.9 23.7 2.3e-96 323.4 23.7 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH27679.1 - 8e-31 107.2 23.0 1.3e-30 106.5 21.7 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily Fungal_trans PF04082.18 KXH27679.1 - 2.1e-05 23.7 0.6 0.00012 21.2 0.6 2.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_2_C PF02836.17 KXH27680.1 - 6.1e-105 350.6 0.0 8.2e-105 350.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.17 KXH27680.1 - 3.2e-68 230.0 0.0 5.8e-68 229.1 0.0 1.5 1 0 0 1 1 1 1 Beta galactosidase small chain Glyco_hydro_2_N PF02837.18 KXH27680.1 - 1.1e-47 162.1 0.2 2.7e-47 160.8 0.2 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain DUF4981 PF16353.5 KXH27680.1 - 1.5e-20 73.4 0.3 1.8e-19 70.0 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function(DUF4981) Glyco_hydro_2 PF00703.21 KXH27680.1 - 8.3e-16 58.6 0.5 2.3e-15 57.2 0.3 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.6 KXH27680.1 - 0.00013 22.5 0.1 0.00063 20.3 0.1 2.2 2 0 0 2 2 2 1 Beta-galactosidase jelly roll domain GMC_oxred_N PF00732.19 KXH27681.1 - 1.9e-58 198.2 0.0 2.5e-58 197.8 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXH27681.1 - 6.7e-28 98.0 0.0 1.1e-27 97.4 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KXH27681.1 - 0.0001 21.5 0.0 0.00015 21.0 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 KXH27681.1 - 0.00027 20.2 0.4 0.43 9.6 0.2 2.1 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.17 KXH27681.1 - 0.0016 17.7 0.1 0.0016 17.7 0.1 1.6 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 KXH27681.1 - 0.0019 17.9 2.7 0.0032 17.1 2.7 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KXH27681.1 - 0.0061 15.4 0.1 0.01 14.7 0.1 1.3 1 0 0 1 1 1 1 Tryptophan halogenase NAD_binding_8 PF13450.6 KXH27681.1 - 0.033 14.4 0.4 0.23 11.7 0.1 2.4 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXH27681.1 - 0.039 13.2 0.0 0.12 11.6 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Glyco_hydro_71 PF03659.14 KXH27683.1 - 3.6e-127 424.3 1.4 4.2e-127 424.0 1.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 DUF4434 PF14488.6 KXH27683.1 - 0.035 14.1 0.0 0.063 13.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4434) Glyco_hydro_71 PF03659.14 KXH27684.1 - 8e-114 380.3 1.8 1e-113 380.0 1.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Opi1 PF08618.10 KXH27685.1 - 1.6e-37 129.8 32.0 2.8e-30 105.9 1.1 5.1 4 1 1 5 5 5 3 Transcription factor Opi1 AA_permease_N PF08403.10 KXH27685.1 - 0.014 14.9 0.3 0.036 13.6 0.3 1.6 1 0 0 1 1 1 0 Amino acid permease N-terminal bZIP_1 PF00170.21 KXH27707.1 - 4.9e-07 29.8 3.1 7.5e-07 29.2 3.1 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KXH27707.1 - 0.0025 17.9 8.0 0.0053 16.8 7.6 1.7 1 1 0 1 1 1 1 Basic region leucine zipper SNAPc19 PF15497.6 KXH27707.1 - 0.25 11.8 0.2 0.25 11.8 0.2 1.8 2 0 0 2 2 2 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 Abhydrolase_6 PF12697.7 KXH27708.1 - 0.00033 21.3 1.2 0.00048 20.8 0.4 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_8 PF06259.12 KXH27708.1 - 0.013 15.2 0.0 0.021 14.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase Ser_hydrolase PF06821.13 KXH27708.1 - 0.049 13.5 0.0 0.12 12.2 0.0 1.6 2 0 0 2 2 2 0 Serine hydrolase Abhydrolase_1 PF00561.20 KXH27708.1 - 0.07 12.8 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Exo_endo_phos PF03372.23 KXH27709.1 - 4.7e-17 62.3 0.2 1.4e-15 57.5 0.0 2.6 2 1 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.7 KXH27709.1 - 1.1e-07 32.1 4.9 0.00018 21.8 0.2 2.6 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXH27709.1 - 7.8e-07 28.8 5.8 1.4e-05 24.7 0.4 2.4 1 1 0 2 2 2 2 Leucine rich repeat TFIIA PF03153.13 KXH27709.1 - 0.76 9.7 8.3 1.1 9.1 8.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit p450 PF00067.22 KXH27757.1 - 2e-42 145.5 0.1 2.3e-42 145.3 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 HEAT_2 PF13646.6 KXH27757.1 - 0.084 13.3 0.3 0.27 11.7 0.3 1.9 1 0 0 1 1 1 0 HEAT repeats AMP-binding_C PF13193.6 KXH27759.1 - 1.7e-19 70.6 0.1 2.2e-19 70.2 0.1 1.2 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 KXH27759.1 - 4.9e-14 51.7 2.3 6.3e-14 51.4 2.3 1.1 1 0 0 1 1 1 1 AMP-binding enzyme QRPTase_C PF01729.19 KXH27760.1 - 6.3e-56 188.8 0.3 7.8e-56 188.5 0.3 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 KXH27760.1 - 2.7e-16 59.4 0.4 5.9e-15 55.1 0.1 2.8 2 1 0 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain IGPS PF00218.21 KXH27760.1 - 0.066 12.4 0.2 0.097 11.8 0.2 1.3 1 0 0 1 1 1 0 Indole-3-glycerol phosphate synthase PLDc_2 PF13091.6 KXH27763.1 - 1.9e-07 31.1 0.1 0.0038 17.1 0.0 2.8 3 0 0 3 3 3 2 PLD-like domain PLDc PF00614.22 KXH27763.1 - 0.11 12.7 1.0 5.2 7.4 0.0 3.2 3 0 0 3 3 3 0 Phospholipase D Active site motif Regulator_TrmB PF11495.8 KXH27763.1 - 0.22 10.7 0.1 0.34 10.1 0.1 1.3 1 0 0 1 1 1 0 Archaeal transcriptional regulator TrmB Fungal_trans PF04082.18 KXH27764.1 - 1.4e-05 24.3 0.0 2.2e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain ABC2_membrane PF01061.24 KXH27765.1 - 6.2e-75 251.2 48.1 1.7e-42 145.3 21.6 2.5 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 KXH27765.1 - 5e-44 150.1 0.2 1.4e-22 80.6 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KXH27765.1 - 1.5e-24 85.7 7.9 5.2e-23 80.7 0.1 3.2 3 0 0 3 3 2 2 CDR ABC transporter ABC2_membrane_3 PF12698.7 KXH27765.1 - 6.7e-10 38.6 8.7 6.7e-10 38.6 8.7 3.0 2 2 0 3 3 3 2 ABC-2 family transporter protein AAA_16 PF13191.6 KXH27765.1 - 2.7e-06 27.9 0.1 0.0031 17.9 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.19 KXH27765.1 - 2.8e-05 23.7 1.4 0.4 10.1 0.0 3.6 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KXH27765.1 - 3.1e-05 23.9 0.3 0.0019 18.1 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_21 PF13304.6 KXH27765.1 - 5.8e-05 23.1 0.0 0.047 13.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KXH27765.1 - 0.00051 19.7 0.3 0.051 13.3 0.1 2.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.6 KXH27765.1 - 0.0015 18.8 0.0 0.34 11.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KXH27765.1 - 0.0066 17.0 0.0 0.76 10.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KXH27765.1 - 0.019 14.9 0.6 0.65 9.9 0.1 2.7 3 0 0 3 3 2 0 NACHT domain AAA_33 PF13671.6 KXH27765.1 - 0.032 14.4 0.0 0.4 10.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 KXH27765.1 - 0.033 13.9 0.1 1.9 8.3 0.1 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Rad17 PF03215.15 KXH27765.1 - 0.034 14.1 0.0 0.52 10.2 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_30 PF13604.6 KXH27765.1 - 0.04 13.6 0.2 0.81 9.4 0.2 2.3 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KXH27765.1 - 0.044 14.2 0.0 13 6.2 0.0 3.1 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 KXH27765.1 - 0.061 12.9 0.1 0.34 10.4 0.1 2.1 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 KXH27765.1 - 0.064 13.5 0.1 3 8.1 0.0 3.1 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase AAA_19 PF13245.6 KXH27765.1 - 0.07 13.5 0.2 7.3 6.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 KXH27765.1 - 0.073 13.0 0.0 6.9 6.5 0.0 2.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea MMR_HSR1 PF01926.23 KXH27765.1 - 0.073 13.2 0.1 4.4 7.4 0.1 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_28 PF13521.6 KXH27765.1 - 0.082 13.2 0.1 0.35 11.1 0.1 2.1 2 0 0 2 2 1 0 AAA domain cobW PF02492.19 KXH27765.1 - 0.085 12.4 0.3 1.6 8.3 0.1 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DnaB_C PF03796.15 KXH27765.1 - 0.092 12.1 0.0 1.9 7.8 0.0 2.2 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain RuvB_N PF05496.12 KXH27765.1 - 0.15 11.8 0.1 18 5.1 0.0 2.4 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 KXH27765.1 - 0.17 11.9 0.1 0.59 10.2 0.1 1.8 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NB-ARC PF00931.22 KXH27765.1 - 0.19 10.9 0.8 6.2 5.9 0.2 2.7 3 0 0 3 3 3 0 NB-ARC domain Peptidase_M99 PF17033.5 KXH27770.1 - 0.2 11.0 0.0 0.31 10.4 0.0 1.2 1 0 0 1 1 1 0 Carboxypeptidase controlling helical cell shape catalytic Cu-oxidase_3 PF07732.15 KXH27771.1 - 3.8e-47 159.2 8.8 2.2e-42 143.8 0.5 3.7 3 2 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 KXH27771.1 - 9.2e-37 125.8 11.2 1e-31 109.5 3.1 3.8 3 1 0 3 3 3 3 Multicopper oxidase Cu-oxidase PF00394.22 KXH27771.1 - 1.9e-34 119.1 0.2 6e-33 114.2 0.1 2.5 2 0 0 2 2 2 1 Multicopper oxidase Zn_clus PF00172.18 KXH27772.1 - 0.0002 21.4 3.3 0.0002 21.4 3.3 2.4 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Shikimate_dh_N PF08501.11 KXH27773.1 - 4.7e-18 65.2 0.0 8.7e-18 64.4 0.0 1.5 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.20 KXH27773.1 - 0.023 14.7 0.0 0.045 13.8 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase AP_endonuc_2 PF01261.24 KXH27774.1 - 1.9e-29 102.7 0.0 3.1e-29 101.9 0.0 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel IucA_IucC PF04183.12 KXH27774.1 - 0.034 13.7 0.1 0.052 13.1 0.1 1.2 1 0 0 1 1 1 0 IucA / IucC family Cu-oxidase_2 PF07731.14 KXH27774.1 - 0.11 12.3 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Multicopper oxidase Zn_clus PF00172.18 KXH27775.1 - 1.8e-06 28.0 11.7 3.2e-06 27.1 11.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXH27775.1 - 3.2e-05 23.1 0.5 0.00038 19.6 0.5 2.2 1 1 0 1 1 1 1 Fungal specific transcription factor domain AAA PF00004.29 KXH27776.1 - 1.2e-17 64.6 0.0 2.6e-17 63.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 KXH27776.1 - 0.0003 21.0 0.1 0.00087 19.5 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KXH27776.1 - 0.00048 20.4 0.2 0.025 14.9 0.0 2.9 2 1 1 3 3 3 1 AAA domain AAA_16 PF13191.6 KXH27776.1 - 0.0016 18.9 0.0 0.0037 17.6 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.6 KXH27776.1 - 0.0071 16.4 0.0 0.018 15.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain Zot PF05707.12 KXH27776.1 - 0.017 14.8 0.1 0.1 12.2 0.0 2.1 1 1 1 2 2 2 0 Zonular occludens toxin (Zot) RsgA_GTPase PF03193.16 KXH27776.1 - 0.032 14.1 0.0 0.089 12.7 0.0 1.7 2 0 0 2 2 2 0 RsgA GTPase Viral_helicase1 PF01443.18 KXH27776.1 - 0.051 13.3 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.22 KXH27776.1 - 0.051 14.0 0.1 1.2 9.6 0.0 2.7 2 0 0 2 2 2 0 RNA helicase IstB_IS21 PF01695.17 KXH27776.1 - 0.057 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_5 PF07728.14 KXH27776.1 - 0.073 13.1 0.0 0.21 11.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 KXH27776.1 - 0.077 12.6 0.0 0.17 11.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KXH27776.1 - 0.091 12.5 0.0 0.21 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 KXH27776.1 - 0.33 10.7 2.4 0.38 10.5 0.0 2.2 3 0 0 3 3 3 0 AAA domain DHquinase_II PF01220.19 KXH27778.1 - 8.9e-62 206.8 0.4 1e-61 206.6 0.4 1.0 1 0 0 1 1 1 1 Dehydroquinase class II SnoaL_4 PF13577.6 KXH27779.1 - 1.7e-08 34.7 0.1 2.4e-08 34.2 0.1 1.1 1 0 0 1 1 1 1 SnoaL-like domain Shikimate_dh_N PF08501.11 KXH27780.1 - 7.3e-22 77.4 0.1 1.3e-21 76.6 0.1 1.4 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 KXH27780.1 - 1.4e-11 43.9 2.3 2.8e-11 43.0 2.3 1.5 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 KXH27780.1 - 4.9e-08 33.1 0.0 7.7e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DHquinase_I PF01487.15 KXH27781.1 - 2.3e-22 80.4 0.0 3.5e-22 79.8 0.0 1.2 1 0 0 1 1 1 1 Type I 3-dehydroquinase Shikimate_dh_N PF08501.11 KXH27781.1 - 2.6e-20 72.4 0.0 7.1e-20 71.1 0.0 1.8 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SKI PF01202.22 KXH27781.1 - 4.5e-16 59.4 0.0 7.9e-16 58.6 0.0 1.4 1 0 0 1 1 1 1 Shikimate kinase SDH_C PF18317.1 KXH27781.1 - 1.5e-07 31.1 0.0 3.2e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 KXH27781.1 - 8.6e-07 29.1 0.0 1.7e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase AAA_33 PF13671.6 KXH27781.1 - 0.036 14.2 0.0 0.089 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain F420_oxidored PF03807.17 KXH27781.1 - 0.076 13.6 0.0 0.7 10.5 0.0 2.3 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_7 PF13241.6 KXH27781.1 - 0.094 13.2 0.0 0.22 12.0 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding ABC2_membrane PF01061.24 KXH27782.1 - 6.6e-79 264.2 49.0 3.7e-43 147.4 18.1 2.6 2 0 0 2 2 2 2 ABC-2 type transporter PDR_CDR PF06422.12 KXH27782.1 - 9.7e-37 124.8 9.8 1.8e-31 107.9 0.0 3.7 4 0 0 4 4 2 2 CDR ABC transporter ABC_tran PF00005.27 KXH27782.1 - 2.8e-32 112.1 0.0 4.9e-16 59.5 0.0 3.2 3 0 0 3 3 3 2 ABC transporter ABC_trans_N PF14510.6 KXH27782.1 - 2.1e-16 60.3 0.2 5.5e-16 59.0 0.2 1.7 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 KXH27782.1 - 1.1e-08 35.6 0.4 0.00014 22.3 0.1 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.6 KXH27782.1 - 2.7e-07 30.3 0.0 1.9e-05 24.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KXH27782.1 - 2.8e-07 30.8 0.3 0.0081 16.3 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.6 KXH27782.1 - 3.6e-07 29.8 1.1 0.0003 20.4 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_18 PF13238.6 KXH27782.1 - 8.6e-06 26.3 0.0 0.0067 17.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KXH27782.1 - 1.5e-05 25.0 0.0 0.003 17.5 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_28 PF13521.6 KXH27782.1 - 4.7e-05 23.7 0.1 0.018 15.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 KXH27782.1 - 6e-05 23.0 0.1 0.034 13.9 0.1 3.0 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KXH27782.1 - 0.00021 20.8 0.0 0.11 11.9 0.0 2.8 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KXH27782.1 - 0.0003 21.1 0.0 0.64 10.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KXH27782.1 - 0.00034 20.4 0.3 0.022 14.5 0.1 2.3 2 0 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.7 KXH27782.1 - 0.0015 17.7 7.8 0.0015 17.7 7.8 2.9 3 0 0 3 3 3 2 ABC-2 family transporter protein AAA_23 PF13476.6 KXH27782.1 - 0.0024 18.4 0.0 0.0062 17.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 KXH27782.1 - 0.0027 18.1 0.3 0.26 11.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 KXH27782.1 - 0.0037 16.9 2.0 0.5 9.9 0.2 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.14 KXH27782.1 - 0.0043 17.1 0.2 0.37 10.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA PF00004.29 KXH27782.1 - 0.0059 17.0 0.0 5.1 7.5 0.0 2.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 KXH27782.1 - 0.0071 16.3 0.5 1.1 9.2 0.0 2.8 3 0 0 3 3 2 1 NACHT domain AAA_14 PF13173.6 KXH27782.1 - 0.013 15.5 0.0 1 9.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KXH27782.1 - 0.015 15.7 0.0 0.89 10.0 0.0 2.6 2 0 0 2 2 2 0 RNA helicase Rad17 PF03215.15 KXH27782.1 - 0.016 15.1 0.0 1.1 9.2 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain IstB_IS21 PF01695.17 KXH27782.1 - 0.03 14.1 0.0 3.8 7.2 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein MMR_HSR1 PF01926.23 KXH27782.1 - 0.033 14.3 0.0 3.1 7.9 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase T2SSE PF00437.20 KXH27782.1 - 0.05 12.7 0.0 2.3 7.2 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein PDR_assoc PF08370.11 KXH27782.1 - 0.12 12.1 0.1 0.12 12.1 0.1 3.8 4 0 0 4 4 3 0 Plant PDR ABC transporter associated Zeta_toxin PF06414.12 KXH27782.1 - 0.14 11.4 0.0 0.99 8.6 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin FHA PF00498.26 KXH27784.1 - 3.2e-18 65.9 0.1 1.1e-17 64.1 0.1 2.0 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KXH27784.1 - 0.00025 21.3 0.0 0.00069 19.9 0.0 1.7 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain GAS PF13851.6 KXH27784.1 - 0.17 11.2 12.2 0.054 12.8 2.8 2.4 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Macoilin PF09726.9 KXH27784.1 - 0.23 10.0 16.0 0.14 10.7 3.0 3.1 3 0 0 3 3 3 0 Macoilin family DUF4047 PF13256.6 KXH27784.1 - 1.7 8.9 5.3 0.3 11.3 1.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4047) Csm1_N PF18504.1 KXH27784.1 - 2.8 8.3 8.2 0.7 10.3 0.5 2.8 2 1 0 2 2 2 0 Csm1 N-terminal domain Romo1 PF10247.9 KXH27785.1 - 4.7e-25 87.7 17.1 4.7e-25 87.7 17.1 1.4 2 0 0 2 2 2 1 Reactive mitochondrial oxygen species modulator 1 Tim17 PF02466.19 KXH27785.1 - 0.01 16.2 4.8 0.012 16.0 4.8 1.2 1 0 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family Transgly_assoc PF04226.13 KXH27785.1 - 0.14 12.5 6.7 0.54 10.5 0.5 2.3 2 0 0 2 2 2 0 Transglycosylase associated protein GMC_oxred_N PF00732.19 KXH27786.1 - 1.1e-64 218.7 0.0 1.5e-64 218.2 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXH27786.1 - 1.1e-35 123.2 0.0 2.1e-35 122.3 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 KXH27786.1 - 8.5e-05 22.3 0.1 0.0059 16.2 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXH27786.1 - 0.00026 20.3 0.3 0.041 13.1 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXH27786.1 - 0.00029 20.1 0.1 0.0021 17.2 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 KXH27786.1 - 0.00034 20.8 0.2 0.00078 19.6 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KXH27786.1 - 0.00044 19.6 0.4 0.0016 17.7 0.1 1.9 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.12 KXH27786.1 - 0.0017 17.5 0.1 0.0025 16.9 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KXH27786.1 - 0.0042 16.4 0.1 0.058 12.6 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXH27786.1 - 0.22 10.2 0.2 0.38 9.4 0.1 1.4 2 0 0 2 2 2 0 HI0933-like protein Asp PF00026.23 KXH27787.1 - 3.4e-48 164.7 0.5 4.8e-48 164.2 0.5 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KXH27787.1 - 1.9e-07 31.5 1.7 3.8e-06 27.2 1.7 2.6 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Sugar_tr PF00083.24 KXH27788.1 - 2.3e-73 247.6 19.4 2.6e-73 247.4 19.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH27788.1 - 3.2e-19 69.1 37.2 1e-11 44.4 14.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KXH27788.1 - 0.00087 17.7 4.2 0.0035 15.7 4.2 1.9 2 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.7 KXH27788.1 - 0.0065 15.4 5.6 0.0065 15.4 5.6 2.2 3 0 0 3 3 3 1 MFS_1 like family MFS_1 PF07690.16 KXH27789.1 - 5e-35 121.1 12.5 6.3e-27 94.4 5.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily 7TM-7TMR_HD PF07698.11 KXH27789.1 - 0.22 11.3 6.5 1.5 8.5 0.3 2.6 2 0 0 2 2 2 0 7TM receptor with intracellular HD hydrolase MFS_1_like PF12832.7 KXH27789.1 - 0.35 9.7 8.4 0.0088 14.9 1.9 1.7 2 0 0 2 2 2 0 MFS_1 like family Fungal_trans_2 PF11951.8 KXH27790.1 - 1.8e-31 109.3 0.0 2.5e-31 108.9 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH27790.1 - 1.1e-06 28.6 12.2 2e-06 27.8 12.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_1 PF00561.20 KXH27791.1 - 2.6e-11 43.7 0.0 9.2e-11 41.9 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXH27791.1 - 1.4e-08 34.3 0.0 2.1e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KXH27791.1 - 2.6e-06 28.2 2.0 1e-05 26.3 2.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.14 KXH27791.1 - 0.002 16.9 0.0 0.0031 16.3 0.0 1.3 1 0 0 1 1 1 1 Ndr family Sugarporin_N PF11471.8 KXH27791.1 - 0.02 14.8 0.4 0.047 13.7 0.4 1.6 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension Peptidase_S15 PF02129.18 KXH27791.1 - 0.036 13.7 1.2 0.26 10.8 0.0 2.5 2 1 1 3 3 3 0 X-Pro dipeptidyl-peptidase (S15 family) Polysacc_deac_1 PF01522.21 KXH27886.1 - 4.8e-33 113.7 0.0 8.8e-33 112.9 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.19 KXH27886.1 - 5.5e-18 65.1 45.7 1.5e-09 38.1 18.3 2.5 2 0 0 2 2 2 2 Chitin recognition protein Glyco_hydro_57 PF03065.15 KXH27886.1 - 5.5e-07 29.1 0.0 2.6e-06 26.9 0.0 1.8 2 1 0 2 2 2 1 Glycosyl hydrolase family 57 DUF2334 PF10096.9 KXH27886.1 - 0.18 11.4 0.2 0.71 9.5 0.2 1.9 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) Glyco_hydro_28 PF00295.17 KXH27887.1 - 1.5e-37 129.4 6.8 2.4e-37 128.8 6.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.6 KXH27887.1 - 0.00012 22.0 7.8 0.00012 22.0 7.8 3.2 2 1 1 3 3 3 2 Right handed beta helix region PTCRA PF15028.6 KXH27887.1 - 0.11 12.2 0.4 0.19 11.4 0.4 1.3 1 0 0 1 1 1 0 Pre-T-cell antigen receptor Bac_rhamnosid6H PF17389.2 KXH27888.1 - 1.8e-118 395.7 1.8 2.6e-118 395.2 1.8 1.2 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_N PF08531.10 KXH27888.1 - 6.7e-54 182.3 0.7 1.5e-53 181.1 0.1 1.9 2 0 0 2 2 2 1 Alpha-L-rhamnosidase N-terminal domain Bac_rhamnosid PF05592.11 KXH27888.1 - 2.3e-32 111.0 0.0 4.2e-32 110.2 0.0 1.5 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase concanavalin-like domain Bac_rhamnosid_C PF17390.2 KXH27888.1 - 1.5e-05 24.6 0.0 0.0016 18.2 0.0 2.8 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase C-terminal domain Fungal_trans PF04082.18 KXH27892.1 - 8.1e-26 90.6 0.0 3.4e-25 88.6 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH27892.1 - 1.2e-10 41.3 12.0 2.2e-10 40.5 12.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain efThoc1 PF11957.8 KXH27892.1 - 0.038 12.7 0.1 0.086 11.5 0.1 1.5 1 0 0 1 1 1 0 THO complex subunit 1 transcription elongation factor Peptidase_M41 PF01434.18 KXH27893.1 - 3.5e-69 232.5 0.0 5.9e-69 231.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 KXH27893.1 - 9.3e-43 145.8 0.0 3.1e-42 144.1 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KXH27893.1 - 1.2e-12 47.4 0.1 3.3e-12 46.0 0.1 1.8 1 0 0 1 1 1 1 AAA+ lid domain FtsH_ext PF06480.15 KXH27893.1 - 4.2e-11 43.2 0.0 9.6e-11 42.0 0.0 1.6 1 0 0 1 1 1 1 FtsH Extracellular AAA_5 PF07728.14 KXH27893.1 - 0.00085 19.3 0.0 0.0032 17.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 KXH27893.1 - 0.0045 16.3 0.0 0.0084 15.4 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_16 PF13191.6 KXH27893.1 - 0.0051 17.2 0.2 0.32 11.4 0.1 2.8 1 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 KXH27893.1 - 0.0063 16.3 0.0 0.028 14.2 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KXH27893.1 - 0.0065 16.7 0.4 1.5 9.1 0.1 3.0 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.6 KXH27893.1 - 0.02 15.3 0.0 0.67 10.4 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_2 PF07724.14 KXH27893.1 - 0.024 14.8 0.0 0.12 12.4 0.0 2.2 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 KXH27893.1 - 0.062 13.0 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 KXH27893.1 - 0.095 12.3 0.5 0.65 9.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain MFS_1 PF07690.16 KXH27894.1 - 6.1e-25 87.9 30.2 6.1e-25 87.9 30.2 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH27894.1 - 3.4e-05 22.9 23.2 0.00053 19.0 23.2 2.6 1 1 0 1 1 1 1 Sugar (and other) transporter IBR PF01485.21 KXH27895.1 - 5.5e-14 52.1 20.6 2.3e-07 30.9 8.0 2.6 2 0 0 2 2 2 2 IBR domain, a half RING-finger domain Pyr_excise PF03013.14 KXH27895.1 - 0.72 9.8 10.1 0.28 11.2 0.6 3.0 3 1 0 3 3 3 0 Pyrimidine dimer DNA glycosylase Glycohydro_20b2 PF14845.6 KXH27895.1 - 9.2 6.9 10.1 5.8 7.6 6.1 2.6 2 1 0 2 2 2 0 beta-acetyl hexosaminidase like CorA PF01544.18 KXH27896.1 - 1.4e-13 50.8 0.1 2.3e-13 50.1 0.1 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DDE_Tnp_ISL3 PF01610.17 KXH27896.1 - 0.04 13.6 0.1 0.084 12.6 0.1 1.5 1 0 0 1 1 1 0 Transposase IMUP PF15761.5 KXH27896.1 - 3.1 8.5 6.9 0.81 10.4 3.5 1.8 2 0 0 2 2 2 0 Immortalisation up-regulated protein DEAD_2 PF06733.15 KXH27898.1 - 3.1e-58 196.3 0.4 7.2e-58 195.1 0.4 1.6 1 0 0 1 1 1 1 DEAD_2 HBB PF06777.11 KXH27898.1 - 9.5e-49 165.7 1.1 1.4e-43 148.8 0.3 2.5 2 0 0 2 2 2 2 Helical and beta-bridge domain Helicase_C_2 PF13307.6 KXH27898.1 - 1.3e-43 149.1 0.0 4.9e-43 147.3 0.0 2.0 2 0 0 2 2 2 1 Helicase C-terminal domain ResIII PF04851.15 KXH27898.1 - 7.4e-05 22.8 0.1 0.0018 18.3 0.1 2.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KXH27898.1 - 0.00022 21.1 0.0 0.042 13.6 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase SNF2_N PF00176.23 KXH27898.1 - 0.0032 16.2 0.0 0.048 12.4 0.0 2.2 1 1 0 1 1 1 1 SNF2 family N-terminal domain AAA_22 PF13401.6 KXH27898.1 - 0.018 15.3 0.2 1.7 8.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 KXH27898.1 - 0.03 13.6 0.5 1.1 8.4 0.0 2.5 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) Stomoxyn PF11585.8 KXH27898.1 - 0.067 13.2 0.2 0.16 12.0 0.2 1.6 1 0 0 1 1 1 0 Insect antimicrobial peptide, stomoxyn PhoH PF02562.16 KXH27898.1 - 0.076 12.5 0.0 4.6 6.6 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein AAA_11 PF13086.6 KXH27898.1 - 0.4 10.4 1.5 1.6 8.5 1.5 1.9 1 1 0 1 1 1 0 AAA domain DDHD PF02862.17 KXH27899.1 - 1.4e-24 87.5 0.0 2.8e-12 47.3 0.0 3.3 2 1 0 3 3 3 2 DDHD domain CENP-U PF13097.6 KXH27899.1 - 0.22 11.5 0.0 0.22 11.5 0.0 1.9 2 0 0 2 2 2 0 CENP-A nucleosome associated complex (NAC) subunit Amidoligase_2 PF12224.8 KXH27912.1 - 2.1e-12 47.3 0.5 2.7e-09 37.1 0.1 2.6 2 1 0 2 2 2 2 Putative amidoligase enzyme HTH_32 PF13565.6 KXH27914.1 - 3.6e-06 27.5 7.8 6.5e-05 23.5 1.1 2.8 2 1 1 3 3 3 2 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KXH27914.1 - 2.6e-05 24.4 0.0 9.6e-05 22.6 0.0 1.9 1 1 1 2 2 2 1 Transposase HTH_7 PF02796.15 KXH27914.1 - 0.0021 18.1 0.6 10 6.3 0.1 3.5 3 0 0 3 3 3 1 Helix-turn-helix domain of resolvase HTH_23 PF13384.6 KXH27914.1 - 0.01 15.6 0.4 0.026 14.3 0.0 1.9 2 0 0 2 2 2 0 Homeodomain-like domain HTH_38 PF13936.6 KXH27914.1 - 0.043 13.6 0.1 0.23 11.3 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_39 PF14090.6 KXH27914.1 - 0.072 12.9 0.1 0.29 10.9 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain Cupin_2 PF07883.11 KXH27915.1 - 4.1e-07 29.6 0.0 7.3e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 KXH27915.1 - 0.053 13.2 0.0 0.096 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF861) GFO_IDH_MocA PF01408.22 KXH27916.1 - 6.8e-11 43.0 0.0 1.9e-10 41.6 0.0 1.7 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KXH27916.1 - 0.00018 21.5 0.0 0.00038 20.5 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain ImpA_N PF06812.12 KXH27916.1 - 0.053 13.6 0.3 0.17 12.0 0.0 2.0 2 0 0 2 2 2 0 ImpA, N-terminal, type VI secretion system RNase_T PF00929.24 KXH27917.1 - 5e-14 53.2 0.0 5.8e-14 53.0 0.0 1.1 1 0 0 1 1 1 1 Exonuclease PGM_PMM_I PF02878.16 KXH27918.1 - 8.5e-33 113.0 0.0 1.3e-32 112.4 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 KXH27918.1 - 6.3e-26 90.8 0.0 1.4e-25 89.7 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 KXH27918.1 - 5.9e-16 59.0 0.0 1.4e-15 57.8 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 KXH27918.1 - 1.2e-06 28.5 0.0 2.6e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain DUF4844 PF16133.5 KXH27918.1 - 0.13 12.8 0.2 0.64 10.6 0.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4844) HMG_box PF00505.19 KXH27920.1 - 9.3e-25 86.8 0.8 1.7e-24 86.0 0.8 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KXH27920.1 - 1.6e-17 63.9 1.2 1.6e-17 63.9 1.2 1.5 2 0 0 2 2 2 1 HMG-box domain Ccdc124 PF06244.12 KXH27920.1 - 0.0016 19.0 0.0 0.0016 19.0 0.0 2.1 1 1 1 2 2 2 1 Coiled-coil domain-containing protein 124 /Oxs1 CHDNT PF08073.12 KXH27920.1 - 0.059 13.3 0.0 0.095 12.7 0.0 1.3 1 0 0 1 1 1 0 CHDNT (NUC034) domain CENP-H PF05837.12 KXH27921.1 - 3.6e-36 124.0 7.2 5.9e-36 123.3 2.7 2.1 2 0 0 2 2 2 1 Centromere protein H (CENP-H) CCDC85 PF10226.9 KXH27921.1 - 0.084 12.5 2.0 0.067 12.9 0.5 1.5 2 0 0 2 2 2 0 CCDC85 family TMF_TATA_bd PF12325.8 KXH27921.1 - 0.11 12.8 7.4 0.04 14.1 2.7 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF1192 PF06698.11 KXH27921.1 - 0.14 12.2 1.6 14 5.8 0.1 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) FAM76 PF16046.5 KXH27921.1 - 0.16 11.3 2.3 0.21 10.9 2.3 1.1 1 0 0 1 1 1 0 FAM76 protein TMCO5 PF14992.6 KXH27921.1 - 0.29 10.7 2.7 0.25 10.9 0.7 1.7 2 0 0 2 2 2 0 TMCO5 family YabA PF06156.13 KXH27921.1 - 0.48 11.1 2.6 1.1 9.9 0.7 2.2 2 1 0 2 2 2 0 Initiation control protein YabA DHR10 PF18595.1 KXH27921.1 - 4.8 7.3 10.7 9.7 6.3 5.3 2.6 2 1 0 2 2 2 0 Designed helical repeat protein 10 domain ATG11 PF10377.9 KXH27922.1 - 5.9e-46 155.7 0.2 5.9e-46 155.7 0.2 5.5 7 1 0 7 7 7 1 Autophagy-related protein 11 Tropomyosin PF00261.20 KXH27922.1 - 0.002 17.5 13.0 0.002 17.5 13.0 6.9 4 1 2 6 6 6 1 Tropomyosin ERM PF00769.19 KXH27922.1 - 0.0036 17.1 24.4 0.0036 17.1 24.4 6.9 2 1 3 7 7 7 1 Ezrin/radixin/moesin family FERM_f0 PF16511.5 KXH27922.1 - 0.0059 16.9 0.5 3.1 8.2 0.0 3.4 3 0 0 3 3 3 1 N-terminal or F0 domain of Talin-head FERM CENP-F_leu_zip PF10473.9 KXH27922.1 - 0.0086 16.1 9.0 0.0086 16.1 9.0 8.4 5 2 4 9 9 9 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 UCH PF00443.29 KXH27922.1 - 0.065 12.7 2.6 0.91 9.0 2.6 3.0 1 1 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase DUF5045 PF16464.5 KXH27922.1 - 1.8 8.9 5.1 2.2 8.7 0.6 3.7 4 1 0 4 4 4 0 Domain of unknown function (DUF5045) Inhibitor_I67 PF11405.8 KXH27922.1 - 6.7 7.1 5.5 15 5.9 5.5 1.5 1 0 0 1 1 1 0 Bromelain inhibitor VI Nop14 PF04147.12 KXH27923.1 - 1.3e-08 33.6 6.5 1.8e-08 33.1 6.5 1.1 1 0 0 1 1 1 1 Nop14-like family Menin PF05053.13 KXH27923.1 - 3 6.1 4.7 4.1 5.6 4.7 1.1 1 0 0 1 1 1 0 Menin Pox_Ag35 PF03286.14 KXH27923.1 - 5.6 6.7 11.7 11 5.8 11.7 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein SDF PF00375.18 KXH27924.1 - 1.5e-89 300.8 33.3 1.8e-89 300.5 33.3 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family Dynamin_N PF00350.23 KXH27925.1 - 2.8e-32 112.1 0.0 5.1e-32 111.2 0.0 1.5 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 KXH27925.1 - 8.6e-25 87.5 0.2 4.5e-24 85.2 0.2 2.0 1 1 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.23 KXH27925.1 - 0.00019 21.5 0.0 0.00084 19.4 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase NA37 PF04245.13 KXH27925.1 - 0.061 12.8 0.1 0.14 11.6 0.1 1.6 1 0 0 1 1 1 0 37-kD nucleoid-associated bacterial protein PAP1 PF08601.10 KXH27927.1 - 0.53 10.0 6.2 0.83 9.3 6.2 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 ABC2_membrane PF01061.24 KXH27928.1 - 1.5e-70 236.9 62.9 1.2e-38 132.7 26.0 3.0 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 KXH27928.1 - 1.5e-35 122.7 0.0 5.3e-17 62.6 0.0 2.6 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.12 KXH27928.1 - 5.5e-33 112.7 4.1 2.7e-28 97.7 0.0 3.8 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.6 KXH27928.1 - 3.5e-15 56.4 0.0 1.2e-14 54.7 0.0 2.0 1 0 0 1 1 1 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 KXH27928.1 - 4.7e-10 39.1 43.2 8.9e-07 28.3 18.9 2.6 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_16 PF13191.6 KXH27928.1 - 7.7e-07 29.7 0.3 0.011 16.1 0.2 2.7 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KXH27928.1 - 1.2e-05 25.3 0.1 0.002 18.0 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_18 PF13238.6 KXH27928.1 - 3.4e-05 24.4 0.1 0.0072 16.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KXH27928.1 - 0.00012 21.7 0.4 0.0036 16.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 KXH27928.1 - 0.00055 19.8 0.7 0.96 9.2 0.0 3.2 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_33 PF13671.6 KXH27928.1 - 0.00071 19.8 0.2 0.089 12.9 0.1 2.5 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 KXH27928.1 - 0.0014 18.1 0.0 0.35 10.3 0.0 3.3 3 1 0 4 4 4 1 RecF/RecN/SMC N terminal domain AAA PF00004.29 KXH27928.1 - 0.0017 18.8 0.4 0.25 11.8 0.1 2.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 KXH27928.1 - 0.0087 15.8 1.1 0.37 10.6 0.2 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain cobW PF02492.19 KXH27928.1 - 0.012 15.2 0.7 4.3 6.9 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 KXH27928.1 - 0.016 14.9 0.3 5.6 6.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KXH27928.1 - 0.019 15.2 0.9 8.8 6.6 0.1 2.8 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KXH27928.1 - 0.022 14.7 0.4 7.9 6.4 0.1 2.6 2 0 0 2 2 2 0 NACHT domain AAA_17 PF13207.6 KXH27928.1 - 0.025 15.0 0.4 10 6.6 0.0 2.9 3 0 0 3 3 2 0 AAA domain AAA_28 PF13521.6 KXH27928.1 - 0.16 12.2 0.6 15 5.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 KXH27928.1 - 0.16 11.8 0.0 5.4 6.9 0.0 2.7 3 0 0 3 3 3 0 Rad17 P-loop domain zf-ribbon_3 PF13248.6 KXH27928.1 - 0.24 10.9 0.2 0.49 9.9 0.2 1.6 1 0 0 1 1 1 0 zinc-ribbon domain GYF_2 PF14237.6 KXH27929.1 - 0.32 10.9 1.8 0.52 10.2 0.0 2.2 2 0 0 2 2 2 0 GYF domain 2 Amidohydro_2 PF04909.14 KXH27930.1 - 9e-17 61.8 0.0 6.5e-16 59.0 0.0 1.9 1 1 0 1 1 1 1 Amidohydrolase Aldo_ket_red PF00248.21 KXH27931.1 - 4e-75 252.7 0.1 4.6e-75 252.5 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Trypsin PF00089.26 KXH27934.1 - 3.6e-07 30.2 0.0 5.7e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 KXH27934.1 - 0.12 13.3 0.0 0.35 11.7 0.0 1.8 1 1 0 1 1 1 0 Trypsin-like peptidase domain Polysacc_deac_1 PF01522.21 KXH27935.1 - 1.9e-25 89.2 0.0 3.3e-25 88.4 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase OTT_1508_deam PF14441.6 KXH27936.1 - 7.7e-13 48.3 0.1 7.7e-13 48.3 0.1 1.8 2 0 0 2 2 2 1 OTT_1508-like deaminase DUF2857 PF11198.8 KXH27936.1 - 0.062 13.1 0.1 0.11 12.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2857) Cas_Cas7 PF05107.12 KXH27936.1 - 0.14 11.7 0.1 0.22 11.1 0.1 1.2 1 0 0 1 1 1 0 CRISPR-associated protein Cas7 Git3 PF11710.8 KXH27937.1 - 9e-22 77.8 6.0 1.7e-21 76.9 6.0 1.4 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.21 KXH27937.1 - 1.3e-10 41.1 0.4 1.4e-10 40.9 0.4 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) GPR_Gpa2_C PF11970.8 KXH27937.1 - 0.0026 17.8 0.3 0.0075 16.3 0.3 1.7 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term Dicty_CAR PF05462.11 KXH27937.1 - 0.046 12.8 7.9 0.094 11.8 7.9 1.4 1 0 0 1 1 1 0 Slime mold cyclic AMP receptor ECH_1 PF00378.20 KXH27940.1 - 3.8e-15 55.9 0.0 5.3e-11 42.3 0.0 2.1 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXH27940.1 - 1.9e-06 27.6 0.2 1.8e-05 24.4 0.0 2.1 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase Acetyltransf_7 PF13508.7 KXH27941.1 - 1.2e-07 32.1 0.0 2.2e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KXH27941.1 - 3.1e-07 30.4 0.0 5.2e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KXH27941.1 - 0.00033 20.7 0.0 0.001 19.1 0.0 1.9 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXH27941.1 - 0.00056 20.1 0.0 0.00074 19.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Lipase_GDSL PF00657.22 KXH27942.1 - 1.6e-06 28.2 0.0 2.1e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase AAA PF00004.29 KXH27943.1 - 1.2e-14 54.8 0.0 4.4e-14 53.0 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KXH27943.1 - 0.0041 17.1 0.0 0.025 14.6 0.0 2.3 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KXH27943.1 - 0.023 15.1 0.0 0.062 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain LPD28 PF18843.1 KXH27943.1 - 0.047 13.3 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Large polyvalent protein associated domain 28 AAA_22 PF13401.6 KXH27943.1 - 0.063 13.5 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KXH27943.1 - 0.11 13.0 0.0 0.35 11.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain Sugar_tr PF00083.24 KXH27944.1 - 5e-112 375.0 21.9 1.4e-111 373.6 21.9 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH27944.1 - 1.1e-25 90.4 41.9 7.1e-20 71.2 14.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Lipase_GDSL_2 PF13472.6 KXH27945.1 - 2.4e-18 67.2 0.2 3.3e-18 66.7 0.2 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KXH27945.1 - 8.7e-09 35.6 0.0 1.9e-08 34.6 0.0 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase PSDC PF12588.8 KXH27945.1 - 0.11 12.4 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Phophatidylserine decarboxylase RTA1 PF04479.13 KXH27946.1 - 8.9e-51 172.4 6.8 1.1e-50 172.1 6.8 1.1 1 0 0 1 1 1 1 RTA1 like protein GST_N_2 PF13409.6 KXH27947.1 - 0.0004 20.6 0.0 0.00059 20.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KXH27947.1 - 0.002 18.5 0.0 0.0031 17.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KXH27947.1 - 0.007 16.4 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Epimerase PF01370.21 KXH27948.1 - 9.2e-08 31.8 0.0 0.00025 20.6 0.0 2.4 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KXH27948.1 - 0.00062 19.4 0.1 0.029 13.9 0.0 2.3 2 0 0 2 2 2 2 NmrA-like family NAD_binding_4 PF07993.12 KXH27948.1 - 0.018 14.2 0.0 0.029 13.5 0.0 1.4 1 0 0 1 1 1 0 Male sterility protein Peptidase_M35 PF02102.15 KXH27949.1 - 9.4e-81 271.5 20.7 1.1e-80 271.2 20.7 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.6 KXH27949.1 - 1.3e-37 129.5 9.2 1.3e-37 129.5 9.2 1.5 2 0 0 2 2 2 1 Lysine-specific metallo-endopeptidase Zn_clus PF00172.18 KXH27950.1 - 5.3e-08 32.9 9.6 1e-07 32.0 9.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KXH27950.1 - 2.2e-07 30.1 0.1 4.5e-07 29.0 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain RPT PF13446.6 KXH27950.1 - 0.19 11.7 0.1 0.46 10.5 0.1 1.6 1 0 0 1 1 1 0 A repeated domain in UCH-protein Peptidase_M28 PF04389.17 KXH27951.1 - 4.7e-33 114.6 0.0 6.7e-33 114.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KXH27951.1 - 9.5e-12 44.8 0.9 1.9e-11 43.8 0.9 1.5 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 KXH27951.1 - 0.0014 18.4 0.0 0.0038 17.0 0.0 1.8 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 HET PF06985.11 KXH27952.1 - 9e-26 91.0 1.1 4.7e-25 88.6 1.1 2.0 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Beta-lactamase PF00144.24 KXH27953.1 - 1.7e-46 159.0 0.1 2.1e-46 158.7 0.1 1.1 1 0 0 1 1 1 1 Beta-lactamase Methyltransf_23 PF13489.6 KXH27954.1 - 1.1e-18 67.6 0.0 1.7e-18 67.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH27954.1 - 5.4e-12 45.7 0.0 4.6e-11 42.7 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH27954.1 - 7e-10 39.5 0.0 1.6e-09 38.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH27954.1 - 1.9e-07 31.7 0.0 9.4e-07 29.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH27954.1 - 5.8e-06 27.0 0.0 0.00011 22.9 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXH27954.1 - 0.001 18.7 0.0 0.0017 17.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.19 KXH27954.1 - 0.0032 17.6 0.0 0.0049 17.0 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_4 PF02390.17 KXH27954.1 - 0.005 16.3 0.0 0.01 15.3 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.13 KXH27954.1 - 0.0096 15.3 0.0 0.017 14.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.9 KXH27954.1 - 0.033 13.9 0.0 0.058 13.1 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase MFS_1_like PF12832.7 KXH27955.1 - 2.4e-05 23.4 2.7 4.6e-05 22.5 2.7 1.6 1 1 0 1 1 1 1 MFS_1 like family OSTbeta PF15048.6 KXH27955.1 - 0.012 15.7 0.6 2.4 8.3 0.0 2.3 2 0 0 2 2 2 0 Organic solute transporter subunit beta protein Ac76 PF05814.11 KXH27955.1 - 0.068 13.2 0.5 0.2 11.7 0.4 1.8 2 0 0 2 2 2 0 Orf76 (Ac76) MRP-L20 PF12824.7 KXH27956.1 - 2.3e-12 47.4 0.4 2.5e-12 47.3 0.4 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 zf-piccolo PF05715.13 KXH27957.1 - 7.1 6.9 13.5 0.87 9.8 6.7 2.5 2 0 0 2 2 2 0 Piccolo Zn-finger Fcf2 PF08698.11 KXH27959.1 - 1.7e-32 111.7 0.7 5.9e-31 106.7 0.0 2.7 1 1 1 2 2 2 1 Fcf2 pre-rRNA processing Ribosomal_S10 PF00338.22 KXH27959.1 - 2.4e-24 85.4 0.0 5e-24 84.4 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e tRNA-synt_1b PF00579.25 KXH27960.1 - 3.6e-60 203.8 0.0 1.1e-37 129.9 0.0 2.0 1 1 1 2 2 2 2 tRNA synthetases class I (W and Y) tRNA-synt_1f PF01921.18 KXH27960.1 - 0.051 12.5 0.0 0.087 11.7 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (K) Importin_rep_3 PF18806.1 KXH27961.1 - 0.00014 21.8 0.0 0.0017 18.3 0.0 2.8 3 0 0 3 3 3 1 Importin 13 repeat Xpo1 PF08389.12 KXH27961.1 - 0.0035 17.4 0.5 0.038 14.1 0.3 2.7 2 0 0 2 2 2 1 Exportin 1-like protein T4SS_TraI PF16932.5 KXH27961.1 - 0.08 12.1 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Type IV secretory system, conjugal DNA-protein transfer Creatinase_N_2 PF16189.5 KXH27962.1 - 5.1e-54 182.7 0.4 3.3e-52 176.8 0.0 2.7 3 0 0 3 3 3 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 KXH27962.1 - 1.4e-43 149.0 0.1 2e-43 148.5 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Peptidase_M24_C PF16188.5 KXH27962.1 - 5.9e-22 77.5 0.3 1.8e-21 76.0 0.3 1.9 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 KXH27962.1 - 7e-22 78.5 0.0 2e-17 64.1 0.0 2.4 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain DUF1576 PF07613.11 KXH27963.1 - 0.022 14.3 0.1 0.038 13.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1576) FUN14 PF04930.15 KXH27963.1 - 5.7 7.4 7.1 27 5.3 5.7 2.5 2 1 0 2 2 2 0 FUN14 family Histone PF00125.24 KXH27964.1 - 2.5e-42 144.4 0.8 2.7e-42 144.2 0.8 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 KXH27964.1 - 2.7e-06 27.5 0.0 3.9e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KXH27964.1 - 0.00011 22.6 0.1 0.00016 22.0 0.1 1.2 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 KXH27964.1 - 0.0063 16.8 0.1 0.0095 16.2 0.1 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KXH27964.1 - 0.081 13.0 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit DER1 PF04511.15 KXH27965.1 - 3e-51 174.1 5.1 3.8e-51 173.8 5.1 1.1 1 0 0 1 1 1 1 Der1-like family ARD PF03079.14 KXH27965.1 - 1.3e-43 148.9 0.4 1.8e-43 148.4 0.4 1.2 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 KXH27965.1 - 5.3e-08 32.5 0.1 1e-07 31.6 0.1 1.4 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 KXH27965.1 - 5.6e-05 23.1 0.3 0.00015 21.7 0.0 1.7 2 0 0 2 2 2 1 AraC-like ligand binding domain adh_short PF00106.25 KXH27966.1 - 3.5e-29 101.7 0.0 4.7e-29 101.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXH27966.1 - 9.3e-20 71.2 0.0 1.3e-19 70.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH27966.1 - 2.5e-09 37.3 0.0 3.8e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXH27966.1 - 1.8e-07 30.9 0.0 3.4e-07 30.0 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXH27966.1 - 0.00018 20.6 0.0 0.00026 20.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KXH27966.1 - 0.00058 19.1 0.0 0.00083 18.6 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KXH27966.1 - 0.00087 18.5 0.0 0.002 17.3 0.0 1.6 2 0 0 2 2 2 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 KXH27966.1 - 0.0078 15.6 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KXH27966.1 - 0.019 14.9 0.0 0.032 14.1 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding DapB_N PF01113.20 KXH27966.1 - 0.12 12.6 0.1 0.18 11.9 0.1 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus EamA PF00892.20 KXH27967.1 - 0.00014 22.1 6.6 0.00014 22.1 6.6 2.2 2 0 0 2 2 2 2 EamA-like transporter family UPF0370 PF13980.6 KXH27967.1 - 0.11 12.6 0.0 0.39 10.8 0.0 2.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0370) PHO4 PF01384.20 KXH27967.1 - 2.4 7.1 17.3 0.084 11.9 6.8 2.5 1 1 1 2 2 2 0 Phosphate transporter family MBOAT PF03062.19 KXH27968.1 - 3.2e-57 194.5 5.0 6.6e-57 193.4 5.0 1.5 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family DUF4604 PF15377.6 KXH27970.1 - 8.5 6.8 14.7 2.6 8.5 3.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) Atx10homo_assoc PF09759.9 KXH27976.1 - 4.9e-13 48.9 0.0 6.4e-13 48.6 0.0 1.2 1 0 0 1 1 1 1 Spinocerebellar ataxia type 10 protein domain Clr5 PF14420.6 KXH27977.1 - 1.1e-19 70.3 3.3 2.6e-19 69.2 3.3 1.6 1 0 0 1 1 1 1 Clr5 domain PH PF00169.29 KXH27978.1 - 6e-05 23.5 0.0 0.00011 22.6 0.0 1.5 1 0 0 1 1 1 1 PH domain Apolipoprotein PF01442.18 KXH27978.1 - 0.011 15.6 1.2 0.014 15.2 0.3 1.6 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain SapC PF07277.11 KXH27978.1 - 0.064 12.8 0.1 0.12 11.9 0.1 1.4 1 0 0 1 1 1 0 SapC Golgin_A5 PF09787.9 KXH27978.1 - 0.11 12.0 2.7 0.18 11.2 0.1 2.1 2 0 0 2 2 2 0 Golgin subfamily A member 5 DUF3106 PF11304.8 KXH27978.1 - 0.13 12.7 0.1 0.63 10.5 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3106) Chorion_2 PF03964.15 KXH27978.1 - 0.39 11.6 5.1 23 5.9 2.5 2.7 1 1 0 2 2 2 0 Chorion family 2 Gln_amidase PF15644.6 KXH27978.1 - 5.4 8.1 6.0 1.3 10.1 0.4 2.8 3 1 0 3 3 3 0 Papain fold toxin 1, glutamine deamidase Arrestin_C PF02752.22 KXH27979.1 - 1.1e-16 61.6 0.0 2.9e-16 60.1 0.0 1.7 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 KXH27979.1 - 7.8e-16 58.4 0.0 1.2e-15 57.8 0.0 1.3 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 KXH27979.1 - 0.0031 17.2 0.0 0.006 16.3 0.0 1.5 1 0 0 1 1 1 1 Arrestin_N terminal like Sarcoglycan_2 PF05510.13 KXH27979.1 - 0.017 13.9 0.0 0.069 11.9 0.0 1.8 2 0 0 2 2 2 0 Sarcoglycan alpha/epsilon WD40 PF00400.32 KXH27980.1 - 2.5e-13 50.2 9.6 0.0012 19.7 0.3 5.8 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXH27980.1 - 7.9e-09 35.7 0.0 0.00021 21.5 0.0 3.9 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KXH27980.1 - 0.00011 22.0 0.1 0.4 10.7 0.0 3.2 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat eIF2A PF08662.11 KXH27980.1 - 0.00028 20.8 0.1 0.00071 19.5 0.1 1.6 1 1 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 KXH27980.1 - 0.0099 14.4 0.0 0.017 13.6 0.0 1.3 1 0 0 1 1 1 1 Cytochrome D1 heme domain EF_assoc_2 PF08356.12 KXH27981.1 - 8.9e-35 118.6 0.0 1.8e-34 117.6 0.0 1.5 1 0 0 1 1 1 1 EF hand associated EF_assoc_1 PF08355.12 KXH27981.1 - 4e-31 106.4 1.1 8.1e-31 105.5 1.1 1.5 1 0 0 1 1 1 1 EF hand associated Ras PF00071.22 KXH27981.1 - 3.5e-21 75.5 0.0 1.5e-13 50.6 0.0 2.2 2 0 0 2 2 2 2 Ras family Roc PF08477.13 KXH27981.1 - 9.2e-14 51.7 0.0 1.1e-08 35.3 0.0 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KXH27981.1 - 1.8e-09 37.7 0.0 0.0002 21.4 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase EF-hand_7 PF13499.6 KXH27981.1 - 9.6e-07 29.2 0.2 0.0018 18.7 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain pair AAA_29 PF13555.6 KXH27981.1 - 6.1e-06 25.9 0.1 0.0059 16.3 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.6 KXH27981.1 - 7.6e-06 26.4 0.1 0.013 15.9 0.1 2.4 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KXH27981.1 - 1.2e-05 25.3 0.0 0.35 10.8 0.0 3.3 2 1 1 3 3 3 2 RsgA GTPase EF-hand_6 PF13405.6 KXH27981.1 - 2.4e-05 23.9 3.7 0.021 14.7 0.3 2.7 2 0 0 2 2 2 2 EF-hand domain AAA_22 PF13401.6 KXH27981.1 - 2.8e-05 24.4 0.0 0.35 11.1 0.0 2.6 2 1 0 2 2 2 2 AAA domain Dynamin_N PF00350.23 KXH27981.1 - 3.4e-05 24.0 0.6 0.61 10.1 0.2 3.3 3 1 1 4 4 3 2 Dynamin family EF-hand_1 PF00036.32 KXH27981.1 - 6.5e-05 22.2 3.6 0.013 15.0 0.8 2.8 2 0 0 2 2 2 1 EF hand ABC_tran PF00005.27 KXH27981.1 - 9.1e-05 23.0 0.0 0.29 11.7 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_24 PF13479.6 KXH27981.1 - 0.0005 19.8 0.0 0.13 12.0 0.0 2.9 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 KXH27981.1 - 0.0012 19.2 0.0 0.43 11.0 0.0 2.6 2 0 0 2 2 2 1 RNA helicase DUF815 PF05673.13 KXH27981.1 - 0.0041 16.3 0.1 1.6 7.8 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) GTP_EFTU PF00009.27 KXH27981.1 - 0.0043 16.6 0.0 5.8 6.4 0.0 3.1 2 1 0 3 3 3 0 Elongation factor Tu GTP binding domain AAA_28 PF13521.6 KXH27981.1 - 0.0047 17.2 0.0 5.2 7.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KXH27981.1 - 0.0077 16.4 0.0 2.2 8.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain IIGP PF05049.13 KXH27981.1 - 0.0086 15.2 0.0 1.7 7.6 0.0 2.3 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) Ploopntkinase3 PF18751.1 KXH27981.1 - 0.012 15.5 0.0 1.6 8.6 0.0 2.4 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 NACHT PF05729.12 KXH27981.1 - 0.015 15.2 0.1 3.3 7.6 0.0 2.9 3 0 0 3 3 2 0 NACHT domain Septin PF00735.18 KXH27981.1 - 0.016 14.5 0.0 0.42 9.8 0.0 2.2 2 0 0 2 2 2 0 Septin EF-hand_10 PF14788.6 KXH27981.1 - 0.019 14.8 1.2 0.35 10.8 0.1 2.4 2 0 0 2 2 2 0 EF hand AAA_18 PF13238.6 KXH27981.1 - 0.022 15.3 0.0 1.8 9.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 KXH27981.1 - 0.041 14.4 0.2 3.5 8.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain Arf PF00025.21 KXH27981.1 - 0.071 12.6 0.0 10 5.5 0.0 2.7 2 1 0 2 2 2 0 ADP-ribosylation factor family AAA_7 PF12775.7 KXH27981.1 - 0.076 12.5 0.0 1.4 8.4 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region Viral_helicase1 PF01443.18 KXH27981.1 - 0.078 12.7 0.0 3.1 7.5 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase EF-hand_5 PF13202.6 KXH27981.1 - 0.11 12.1 6.1 0.29 10.7 2.7 2.7 2 0 0 2 2 2 0 EF hand SMC_N PF02463.19 KXH27981.1 - 0.12 11.8 0.1 4.4 6.7 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 KXH27981.1 - 0.15 11.7 0.1 15 5.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain AIG1 PF04548.16 KXH27981.1 - 0.24 10.7 0.2 1.2 8.4 0.2 2.0 2 0 0 2 2 2 0 AIG1 family EF-hand_8 PF13833.6 KXH27981.1 - 1.6 8.6 4.0 9.9 6.1 0.8 2.5 2 0 0 2 2 2 0 EF-hand domain pair ECH_1 PF00378.20 KXH27983.1 - 2e-40 138.7 0.0 4.8e-40 137.5 0.0 1.5 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXH27983.1 - 6.6e-34 117.9 0.0 2e-31 109.7 0.0 2.1 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase SMC_N PF02463.19 KXH28003.1 - 1.3e-24 86.9 0.3 2.8e-24 85.8 0.3 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KXH28003.1 - 8.4e-17 62.3 1.7 8.4e-17 62.3 1.7 5.5 2 2 2 4 4 4 1 AAA domain AAA_15 PF13175.6 KXH28003.1 - 6.3e-15 55.8 1.3 9.5e-08 32.1 0.0 2.8 2 1 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 KXH28003.1 - 1.2e-05 25.4 6.4 0.017 15.0 0.0 3.6 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KXH28003.1 - 0.024 14.4 0.0 0.049 13.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.29 KXH28003.1 - 0.085 13.3 0.0 0.54 10.7 0.0 2.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NPV_P10 PF05531.12 KXH28003.1 - 0.27 11.7 17.3 0.21 12.1 0.1 6.3 4 2 0 4 4 4 0 Nucleopolyhedrovirus P10 protein CENP-F_leu_zip PF10473.9 KXH28003.1 - 1.7 8.7 76.7 0.014 15.4 17.2 6.0 3 2 2 6 6 6 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Pkinase PF00069.25 KXH28004.1 - 3.6e-67 226.5 0.0 5.1e-66 222.7 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Fungal_KA1 PF16797.5 KXH28004.1 - 1.1e-39 134.7 0.0 2.3e-39 133.7 0.0 1.6 1 0 0 1 1 1 1 Fungal kinase associated-1 domain Pkinase_Tyr PF07714.17 KXH28004.1 - 3.1e-33 115.1 0.0 9.6e-33 113.6 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KXH28004.1 - 0.00011 21.6 0.0 0.00017 21.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KXH28004.1 - 0.0012 18.8 0.0 0.015 15.2 0.0 2.2 1 1 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 KXH28004.1 - 0.004 16.8 0.1 0.055 13.1 0.1 2.4 2 0 0 2 2 2 1 RIO1 family Choline_kinase PF01633.20 KXH28004.1 - 0.016 14.8 0.1 0.036 13.7 0.1 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 KXH28004.1 - 0.016 14.5 0.0 0.037 13.4 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KXH28004.1 - 0.032 13.2 0.0 0.066 12.1 0.0 1.5 1 0 0 1 1 1 0 Haspin like kinase domain Malate_synthase PF01274.22 KXH28005.1 - 2e-228 758.9 0.0 2.3e-228 758.7 0.0 1.0 1 0 0 1 1 1 1 Malate synthase MFS_1 PF07690.16 KXH28031.1 - 1e-26 93.8 25.7 1.4e-26 93.2 25.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 KXH28031.1 - 8.6e-09 35.1 4.0 1.8e-08 34.1 4.0 1.4 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB DUF2575 PF10837.8 KXH28031.1 - 0.11 12.9 0.2 1.4 9.2 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2575) DUF1453 PF07301.11 KXH28031.1 - 1.8 8.6 6.9 1 9.3 0.9 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1453) Sugar_tr PF00083.24 KXH28032.1 - 8.3e-83 278.7 22.1 1.1e-82 278.3 22.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH28032.1 - 5.7e-29 101.1 22.7 5.7e-29 101.1 22.7 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KXH28032.1 - 8.1e-06 24.5 1.9 1.4e-05 23.7 1.9 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF1761 PF08570.10 KXH28032.1 - 0.37 11.0 12.8 0.82 9.9 6.8 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1761) adh_short PF00106.25 KXH28033.1 - 7.8e-19 67.9 0.0 7.6e-17 61.4 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXH28033.1 - 2.5e-11 43.6 0.0 7.1e-10 38.8 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH28033.1 - 2.9e-06 27.3 0.0 4.2e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 KR domain AAA_16 PF13191.6 KXH28034.1 - 5.4e-07 30.1 0.4 5.8e-06 26.8 0.0 3.0 5 0 0 5 5 5 1 AAA ATPase domain NACHT PF05729.12 KXH28034.1 - 7.3e-06 26.0 0.1 0.00015 21.8 0.1 2.5 1 1 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 KXH28034.1 - 0.02 15.1 0.0 0.15 12.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KXH28034.1 - 0.045 14.1 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.6 KXH28034.1 - 0.048 14.2 0.0 0.56 10.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KXH28034.1 - 0.068 12.9 0.2 0.13 12.0 0.2 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Aminotran_1_2 PF00155.21 KXH28036.1 - 2.1e-64 218.0 0.0 3.1e-64 217.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aa_trans PF01490.18 KXH28037.1 - 5.2e-29 101.2 29.5 6.6e-29 100.8 29.5 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF2208 PF09973.9 KXH28037.1 - 0.13 11.8 2.6 0.25 10.9 0.3 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2208) DUF2236 PF09995.9 KXH28038.1 - 1.8e-07 31.6 0.0 2.8e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) Sugar_tr PF00083.24 KXH28039.1 - 7.9e-76 255.7 21.1 9.7e-76 255.4 21.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH28039.1 - 1.1e-18 67.3 34.8 2.5e-15 56.3 24.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Anoctamin PF04547.12 KXH28039.1 - 2.5 6.9 6.7 1.1 8.1 1.2 2.6 2 1 0 2 2 2 0 Calcium-activated chloride channel Ank_4 PF13637.6 KXH28040.1 - 7.2e-29 99.8 3.0 0.022 15.3 0.0 11.3 7 3 4 11 11 11 9 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXH28040.1 - 6.8e-20 71.4 1.9 0.0004 20.9 0.0 7.1 4 2 3 7 7 7 6 Ankyrin repeats (3 copies) Ank PF00023.30 KXH28040.1 - 1.4e-19 69.6 11.5 0.0023 18.3 0.1 9.7 9 3 0 9 9 9 6 Ankyrin repeat Ank_5 PF13857.6 KXH28040.1 - 2.2e-14 53.3 10.5 0.36 11.2 0.0 9.2 9 1 1 10 10 10 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXH28040.1 - 3.9e-14 51.4 2.2 2.8 8.8 0.0 10.3 11 2 0 11 11 11 4 Ankyrin repeat DUF4449 PF14613.6 KXH28041.1 - 4.5e-05 23.6 0.1 0.00052 20.2 0.0 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF4449) ECH_1 PF00378.20 KXH28042.1 - 1.3e-68 231.0 0.1 1.5e-68 230.9 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXH28042.1 - 2.3e-31 109.5 0.4 3e-28 99.3 0.3 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase SDH_sah PF01972.16 KXH28042.1 - 0.046 12.7 0.1 0.12 11.4 0.1 1.4 1 1 0 1 1 1 0 Serine dehydrogenase proteinase AMP-binding PF00501.28 KXH28044.1 - 4.4e-86 289.1 0.0 3.1e-85 286.3 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme FtsX PF02687.21 KXH28044.1 - 1.9 9.0 8.8 0.25 11.8 3.8 2.1 2 0 0 2 2 2 0 FtsX-like permease family DUF647 PF04884.14 KXH28045.1 - 1e-90 303.6 0.1 1.4e-90 303.1 0.1 1.2 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis TauE PF01925.19 KXH28045.1 - 0.094 12.3 5.1 0.031 13.9 1.1 1.9 1 1 1 2 2 2 0 Sulfite exporter TauE/SafE Alpha-amylase PF00128.24 KXH28046.1 - 1.6e-23 83.9 1.8 3e-23 82.9 1.8 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1939 PF09154.10 KXH28046.1 - 0.00045 20.3 0.0 0.0012 19.0 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1939) Glyco_hydro_70 PF02324.16 KXH28046.1 - 0.0015 16.8 0.3 0.54 8.4 0.0 3.0 2 1 0 3 3 3 3 Glycosyl hydrolase family 70 ABC_tran PF00005.27 KXH28050.1 - 5.4e-36 124.1 0.0 1.8e-35 122.4 0.0 2.0 2 0 0 2 2 2 1 ABC transporter ABC_membrane PF00664.23 KXH28050.1 - 9.8e-32 110.7 9.8 9.8e-32 110.7 9.8 2.1 3 0 0 3 3 3 1 ABC transporter transmembrane region SMC_N PF02463.19 KXH28050.1 - 1.8e-06 27.6 0.5 0.00053 19.5 0.0 2.4 1 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KXH28050.1 - 0.00038 20.7 0.2 0.0019 18.5 0.2 2.1 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KXH28050.1 - 0.0023 17.7 0.0 0.0042 16.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KXH28050.1 - 0.0032 17.2 0.3 0.0084 15.8 0.3 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 KXH28050.1 - 0.017 15.5 0.9 0.16 12.4 0.9 2.3 1 1 0 1 1 1 0 AAA ATPase domain AAA_15 PF13175.6 KXH28050.1 - 0.019 14.7 0.0 0.032 14.0 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain SbcCD_C PF13558.6 KXH28050.1 - 0.032 14.5 0.4 0.45 10.8 0.4 2.6 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_10 PF12846.7 KXH28050.1 - 0.046 12.6 0.1 0.086 11.8 0.1 1.5 1 1 0 1 1 1 0 AAA-like domain AAA_21 PF13304.6 KXH28050.1 - 0.055 13.3 0.1 0.44 10.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KXH28050.1 - 0.11 12.4 0.0 0.31 10.9 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase ATP-synt_ab PF00006.25 KXH28050.1 - 0.16 11.6 0.0 5.5 6.6 0.0 2.4 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF87 PF01935.17 KXH28050.1 - 0.17 12.0 0.5 0.35 10.9 0.1 1.6 2 0 0 2 2 2 0 Helicase HerA, central domain UbiA PF01040.18 KXH28051.1 - 3.2e-34 118.4 14.8 5.1e-34 117.7 14.8 1.3 1 0 0 1 1 1 1 UbiA prenyltransferase family LCM PF04072.14 KXH28052.1 - 4.2e-18 66.0 0.0 5.7e-18 65.5 0.0 1.1 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase DUF2678 PF10856.8 KXH28053.1 - 0.009 15.9 8.8 0.69 9.9 0.3 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF2678) DUF5367 PF17329.2 KXH28053.1 - 0.038 14.1 0.9 0.038 14.1 0.9 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5367) DUF202 PF02656.15 KXH28053.1 - 0.21 12.1 1.0 1.3 9.5 0.5 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF202) SelK_SelG PF10961.8 KXH28053.1 - 0.67 10.6 4.7 2.1 9.0 3.5 2.3 1 1 1 2 2 2 0 Selenoprotein SelK_SelG adh_short PF00106.25 KXH28054.1 - 1.4e-26 93.1 0.4 2.2e-22 79.5 0.2 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXH28054.1 - 3.9e-16 59.3 1.9 6.1e-15 55.4 1.9 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH28054.1 - 1.1e-05 25.5 0.2 1.8e-05 24.8 0.2 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXH28054.1 - 0.0027 17.2 0.2 0.0067 15.9 0.2 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXH28054.1 - 0.0048 16.3 1.1 0.067 12.6 1.1 2.0 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 KXH28055.1 - 2.1e-37 128.5 0.5 3.4e-37 127.8 0.5 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXH28055.1 - 1.6e-29 103.1 0.3 2.4e-28 99.3 0.3 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH28055.1 - 1.1e-07 31.9 0.1 1.5e-07 31.5 0.1 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KXH28055.1 - 0.00051 19.3 0.0 0.00074 18.7 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KXH28055.1 - 0.006 16.1 0.8 0.028 13.9 0.8 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 KXH28055.1 - 0.017 15.2 0.9 0.039 14.0 0.9 1.7 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 KXH28055.1 - 0.032 14.5 0.3 0.074 13.3 0.3 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain PA PF02225.22 KXH28055.1 - 0.064 13.3 0.5 0.12 12.4 0.5 1.5 1 0 0 1 1 1 0 PA domain p450 PF00067.22 KXH28056.1 - 1.8e-69 234.7 0.0 2.2e-69 234.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 NAD_binding_1 PF00175.21 KXH28057.1 - 5.1e-32 110.8 0.0 8.1e-32 110.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KXH28057.1 - 2.7e-27 95.0 0.0 4.3e-27 94.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.28 KXH28057.1 - 1.3e-22 79.7 0.6 2.9e-22 78.6 0.3 1.8 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 KXH28057.1 - 2.8e-05 24.3 0.0 0.002 18.3 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 KXH28057.1 - 0.0065 16.7 0.0 0.024 14.9 0.0 2.0 1 1 1 2 2 2 1 Siderophore-interacting FAD-binding domain GHMP_kinases_N PF00288.26 KXH28057.1 - 0.2 11.9 2.9 0.64 10.3 2.9 1.9 1 0 0 1 1 1 0 GHMP kinases N terminal domain DUF1768 PF08719.11 KXH28058.1 - 6.8e-50 169.4 0.1 8e-50 169.2 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) ADH_N PF08240.12 KXH28060.1 - 8.5e-21 73.9 4.1 1.4e-20 73.2 4.1 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXH28060.1 - 3.8e-15 56.0 0.0 9.4e-15 54.7 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXH28060.1 - 0.0019 19.2 0.0 0.0039 18.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ATPgrasp_N PF18130.1 KXH28060.1 - 0.0027 18.2 0.0 0.0049 17.4 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp N-terminal domain XdhC_C PF13478.6 KXH28060.1 - 0.0063 17.0 0.0 0.014 15.9 0.0 1.6 1 0 0 1 1 1 1 XdhC Rossmann domain 2-Hacid_dh_C PF02826.19 KXH28060.1 - 0.0097 15.3 0.1 0.017 14.5 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KXH28060.1 - 0.019 14.3 0.1 0.057 12.7 0.1 1.8 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain LysM PF01476.20 KXH28061.1 - 2e-11 43.7 0.0 7.1e-07 29.2 0.0 2.4 2 0 0 2 2 2 2 LysM domain Glyco_hydro_71 PF03659.14 KXH28062.1 - 8.5e-141 469.1 1.4 1.2e-140 468.6 1.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 DUF1653 PF07866.11 KXH28063.1 - 0.045 14.1 0.1 0.045 14.1 0.1 2.6 4 0 0 4 4 4 0 Protein of unknown function (DUF1653) RecO_N_2 PF13114.6 KXH28063.1 - 0.071 12.8 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 RecO N terminal Glyco_hydro_43 PF04616.14 KXH28064.1 - 4.5e-107 357.7 0.3 7.6e-107 356.9 0.3 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 KXH28064.1 - 1.4e-46 158.8 0.0 2.2e-46 158.2 0.0 1.2 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain FAD_binding_4 PF01565.23 KXH28065.1 - 3e-17 62.6 0.0 2.1e-16 59.9 0.1 2.3 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 KXH28065.1 - 3.6e-13 49.4 0.0 7e-13 48.5 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.10 KXH28065.1 - 0.17 11.2 0.0 0.3 10.5 0.0 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding Lactonase PF10282.9 KXH28066.1 - 1.4e-67 228.4 0.0 1.9e-67 228.0 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller HET PF06985.11 KXH28067.1 - 1.2e-37 129.5 0.0 1.4e-31 109.9 0.0 2.4 2 0 0 2 2 2 2 Heterokaryon incompatibility protein (HET) PS_Dcarbxylase PF02666.15 KXH28068.1 - 1.7e-37 128.9 0.0 6.5e-37 127.0 0.0 1.8 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase PSDC PF12588.8 KXH28068.1 - 5.5e-34 117.1 0.0 8.4e-34 116.6 0.0 1.3 1 0 0 1 1 1 1 Phophatidylserine decarboxylase RnfC_N PF13375.6 KXH28068.1 - 0.0065 16.4 0.0 2.7 8.0 0.0 3.0 3 0 0 3 3 3 2 RnfC Barrel sandwich hybrid domain DUF2706 PF10913.8 KXH28068.1 - 0.16 11.8 0.9 0.37 10.7 0.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2706) DUF4246 PF14033.6 KXH28069.1 - 2e-171 571.1 0.0 2.4e-171 570.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) HTH_33 PF13592.6 KXH28069.1 - 0.18 11.5 1.8 1.5 8.5 0.0 2.7 3 0 0 3 3 3 0 Winged helix-turn helix Hemerythrin PF01814.23 KXH28070.1 - 1.6e-11 44.9 4.7 2.2e-11 44.5 4.7 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain DUF5484 PF17583.2 KXH28071.1 - 0.15 11.8 0.3 7.1 6.4 0.0 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5484) eIF-3c_N PF05470.12 KXH28073.1 - 9.7e-178 592.2 24.4 9.7e-178 592.2 24.4 3.1 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 KXH28073.1 - 2.7e-14 53.5 0.2 1.4e-13 51.3 0.2 2.4 1 0 0 1 1 1 1 PCI domain DUF2779 PF11074.8 KXH28073.1 - 0.083 13.4 2.8 1.3 9.5 0.1 3.6 3 1 0 3 3 3 0 Domain of unknown function(DUF2779) DASH_Ask1 PF08655.10 KXH28073.1 - 0.18 11.7 0.5 0.59 10.1 0.1 2.1 2 0 0 2 2 2 0 DASH complex subunit Ask1 PSII_Pbs27 PF13326.6 KXH28073.1 - 0.54 10.6 5.3 0.72 10.2 2.9 2.4 1 1 1 2 2 2 0 Photosystem II Pbs27 PROCN PF08083.11 KXH28074.1 - 1.4e-233 774.9 9.4 1.4e-233 774.9 9.4 1.9 2 0 0 2 2 2 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 KXH28074.1 - 6e-128 425.2 1.1 1.3e-127 424.1 1.1 1.6 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 KXH28074.1 - 5.7e-89 296.1 1.8 1.8e-88 294.5 1.8 2.0 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.11 KXH28074.1 - 9.3e-78 259.4 3.3 9.3e-78 259.4 3.3 2.0 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.9 KXH28074.1 - 3.8e-71 237.4 0.1 7.7e-71 236.4 0.1 1.6 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.9 KXH28074.1 - 1.4e-46 156.7 0.1 4.2e-46 155.2 0.1 1.9 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.11 KXH28074.1 - 1.5e-44 150.9 0.4 4.1e-44 149.4 0.0 2.0 2 0 0 2 2 2 1 PROCT (NUC072) domain Myb_DNA-bind_6 PF13921.6 KXH28075.1 - 2.2e-14 53.4 0.2 1e-07 32.0 0.0 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KXH28075.1 - 9.1e-13 48.2 0.1 2.1e-05 24.6 0.1 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain AtuA PF07287.11 KXH28075.1 - 0.16 10.6 0.0 0.24 10.1 0.0 1.1 1 0 0 1 1 1 0 Acyclic terpene utilisation family protein AtuA HTH_AsnC-type PF13404.6 KXH28075.1 - 0.17 11.8 0.0 1.2 9.0 0.0 2.2 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain DUF4085 PF13315.6 KXH28075.1 - 0.17 11.5 0.1 0.25 10.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4085) RPN6_N PF18055.1 KXH28097.1 - 1.9e-46 157.2 2.2 1.9e-46 157.2 2.2 2.7 3 1 0 3 3 3 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 KXH28097.1 - 3.3e-22 79.0 2.1 4.2e-22 78.6 0.4 2.1 3 0 0 3 3 2 1 PCI domain RPN6_C_helix PF18503.1 KXH28097.1 - 1.2e-07 31.3 0.9 2.9e-07 30.1 0.9 1.8 1 0 0 1 1 1 1 26S proteasome subunit RPN6 C-terminal helix domain DDRGK PF09756.9 KXH28097.1 - 6.6e-05 22.6 0.8 6.6e-05 22.6 0.8 2.0 2 0 0 2 2 2 1 DDRGK domain TPR_7 PF13176.6 KXH28097.1 - 0.0002 21.1 3.2 0.45 10.6 0.5 4.4 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KXH28097.1 - 0.00033 20.1 2.2 0.00033 20.1 2.2 2.9 2 2 0 2 2 2 1 MalT-like TPR region TPR_12 PF13424.6 KXH28097.1 - 0.00089 19.5 20.0 0.022 15.1 1.7 5.7 4 1 2 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.28 KXH28097.1 - 0.0029 17.4 1.4 2.1 8.3 0.1 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat INT_SG_DDX_CT_C PF15300.6 KXH28097.1 - 0.023 14.5 0.0 0.053 13.3 0.0 1.6 1 0 0 1 1 1 0 INTS6/SAGE1/DDX26B/CT45 C-terminus TPR_8 PF13181.6 KXH28097.1 - 0.025 14.8 5.2 11 6.5 0.1 5.3 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_10 PF13374.6 KXH28097.1 - 0.032 14.1 0.7 13 5.8 0.0 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 KXH28097.1 - 0.034 14.8 4.1 86 4.1 0.1 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat HTH_Crp_2 PF13545.6 KXH28097.1 - 0.058 13.4 0.1 0.42 10.6 0.0 2.4 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain DUF4456 PF14644.6 KXH28097.1 - 0.097 12.3 5.4 7.6 6.2 3.4 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4456) TPR_4 PF07721.14 KXH28097.1 - 0.13 12.9 0.2 1.1 10.1 0.0 2.8 2 0 0 2 2 1 0 Tetratricopeptide repeat TPR_2 PF07719.17 KXH28097.1 - 0.44 10.8 8.5 30 5.0 0.0 5.1 5 1 1 6 6 6 0 Tetratricopeptide repeat DUF2564 PF10819.8 KXH28097.1 - 1.9 8.9 5.5 4.2 7.8 1.7 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2564) TPR_14 PF13428.6 KXH28097.1 - 2.2 9.3 10.7 43 5.3 0.1 5.2 5 1 1 6 6 5 0 Tetratricopeptide repeat TPR_11 PF13414.6 KXH28097.1 - 2.3 8.0 6.6 9.7 6.0 0.2 3.8 4 0 0 4 4 4 0 TPR repeat WD40 PF00400.32 KXH28098.1 - 2.9e-33 113.3 9.3 4.6e-08 33.6 0.0 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat Sof1 PF04158.14 KXH28098.1 - 1.2e-30 105.6 14.6 2.3e-30 104.7 14.6 1.5 1 0 0 1 1 1 1 Sof1-like domain ANAPC4_WD40 PF12894.7 KXH28098.1 - 4.4e-11 42.9 0.1 0.00024 21.3 0.0 5.0 2 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 KXH28098.1 - 0.0014 17.0 0.0 0.034 12.5 0.0 2.4 1 1 0 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz Ge1_WD40 PF16529.5 KXH28098.1 - 0.0056 15.7 0.1 5.3 5.9 0.0 3.2 2 2 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 KXH28098.1 - 0.019 13.5 0.2 6.6 5.1 0.0 3.0 1 1 1 3 3 3 0 Cytochrome D1 heme domain adh_short PF00106.25 KXH28099.1 - 7.6e-40 136.4 0.3 1.1e-39 135.9 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXH28099.1 - 2e-32 112.6 0.1 3.8e-32 111.7 0.1 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH28099.1 - 1.2e-10 41.6 3.5 1.1e-09 38.5 3.5 2.0 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KXH28099.1 - 0.0026 17.3 0.2 0.0046 16.4 0.1 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family CRAL_TRIO PF00650.20 KXH28187.1 - 6.9e-41 139.6 0.0 9.7e-41 139.1 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KXH28187.1 - 5e-14 52.2 0.6 5e-14 52.2 0.6 1.6 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KXH28187.1 - 0.011 15.8 0.0 0.016 15.3 0.0 1.2 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain O-FucT PF10250.9 KXH28215.1 - 1.3e-10 41.6 0.0 9.6e-10 38.7 0.0 2.1 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Phage-tail_3 PF13550.6 KXH28215.1 - 0.017 15.0 0.1 0.032 14.1 0.1 1.4 1 0 0 1 1 1 0 Putative phage tail protein Ribosomal_L23 PF00276.20 KXH28286.1 - 7.5e-12 45.5 0.2 1.4e-11 44.6 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L23 DJ-1_PfpI PF01965.24 KXH28287.1 - 1.1e-11 44.8 0.0 2.3e-11 43.8 0.0 1.5 2 0 0 2 2 2 1 DJ-1/PfpI family ThiJ_like PF17124.5 KXH28287.1 - 0.012 15.3 0.0 0.016 14.9 0.0 1.1 1 0 0 1 1 1 0 ThiJ/PfpI family-like Hamartin PF04388.12 KXH28288.1 - 2.1e-26 92.9 1.5 2.1e-26 92.9 1.5 3.5 2 1 1 3 3 3 2 Hamartin protein Tuberin PF03542.16 KXH28288.1 - 0.064 12.4 0.1 0.064 12.4 0.1 1.9 2 0 0 2 2 2 0 Tuberin Macoilin PF09726.9 KXH28288.1 - 0.27 9.7 45.3 0.8 8.2 45.3 1.7 1 1 0 1 1 1 0 Macoilin family ABC_membrane PF00664.23 KXH28289.1 - 1.1e-82 277.8 32.8 3.2e-46 158.2 7.9 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KXH28289.1 - 1e-60 204.2 0.0 2.9e-29 102.3 0.0 3.1 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KXH28289.1 - 4.1e-15 55.8 0.0 2.2e-07 30.5 0.0 3.9 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KXH28289.1 - 8.1e-09 35.9 0.2 0.0028 18.0 0.0 3.9 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KXH28289.1 - 1.5e-08 35.2 1.4 0.0014 19.1 0.2 3.9 2 2 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 KXH28289.1 - 1.3e-07 31.3 0.5 0.0018 17.9 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KXH28289.1 - 7.3e-07 29.2 0.0 0.042 13.7 0.0 2.7 3 0 0 3 3 2 2 RsgA GTPase AAA_21 PF13304.6 KXH28289.1 - 1e-05 25.5 0.1 0.28 10.9 0.0 3.3 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC_ATPase PF09818.9 KXH28289.1 - 1.7e-05 23.9 0.2 0.022 13.5 0.0 2.4 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_7 PF12775.7 KXH28289.1 - 4.2e-05 23.1 0.0 0.14 11.7 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_5 PF07728.14 KXH28289.1 - 4.9e-05 23.4 0.0 0.71 9.9 0.0 3.5 4 0 0 4 4 4 2 AAA domain (dynein-related subfamily) AAA PF00004.29 KXH28289.1 - 5.4e-05 23.6 2.1 0.79 10.1 0.4 4.2 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 KXH28289.1 - 0.0001 22.1 0.3 0.032 14.0 0.0 3.3 4 0 0 4 4 3 1 IstB-like ATP binding protein SbcCD_C PF13558.6 KXH28289.1 - 0.00018 21.7 3.6 0.74 10.1 0.2 4.1 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.6 KXH28289.1 - 0.00018 22.1 0.0 0.68 10.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 KXH28289.1 - 0.00021 21.2 0.0 0.026 14.2 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.6 KXH28289.1 - 0.00022 21.0 2.6 1.5 8.5 0.0 4.2 5 0 0 5 5 4 2 AAA domain Rad17 PF03215.15 KXH28289.1 - 0.00034 20.6 0.0 0.4 10.6 0.0 2.4 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_23 PF13476.6 KXH28289.1 - 0.00046 20.8 0.3 0.99 9.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 KXH28289.1 - 0.001 19.3 0.0 1.9 8.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 KXH28289.1 - 0.0011 19.1 0.0 1.6 8.9 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_24 PF13479.6 KXH28289.1 - 0.0015 18.3 0.0 1.1 8.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.22 KXH28289.1 - 0.0036 17.0 0.0 3.3 7.3 0.0 2.6 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain ATP_bind_1 PF03029.17 KXH28289.1 - 0.0054 16.6 0.0 1.4 8.7 0.0 2.4 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_25 PF13481.6 KXH28289.1 - 0.0069 16.0 2.5 4.5 6.8 0.0 4.2 5 0 0 5 5 5 1 AAA domain NB-ARC PF00931.22 KXH28289.1 - 0.02 14.1 0.1 9.2 5.4 0.0 2.9 4 0 0 4 4 3 0 NB-ARC domain ATP-synt_ab PF00006.25 KXH28289.1 - 0.021 14.5 0.0 4.3 6.9 0.0 2.6 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain TniB PF05621.11 KXH28289.1 - 0.028 13.8 0.1 16 4.8 0.0 3.5 4 0 0 4 4 4 0 Bacterial TniB protein RNA_helicase PF00910.22 KXH28289.1 - 0.034 14.5 0.0 9.4 6.7 0.0 2.6 2 0 0 2 2 2 0 RNA helicase Roc PF08477.13 KXH28289.1 - 0.056 13.7 0.0 14 5.9 0.0 3.1 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase AAA_17 PF13207.6 KXH28289.1 - 0.069 13.6 0.0 17 5.8 0.0 3.3 3 0 0 3 3 3 0 AAA domain APS_kinase PF01583.20 KXH28289.1 - 0.069 13.0 0.0 13 5.6 0.0 3.6 4 0 0 4 4 3 0 Adenylylsulphate kinase NTPase_1 PF03266.15 KXH28289.1 - 0.08 12.8 0.3 54 3.6 0.0 3.6 4 0 0 4 4 4 0 NTPase DEAD PF00270.29 KXH28289.1 - 0.081 12.7 0.0 88 2.8 0.0 3.7 3 1 0 3 3 3 0 DEAD/DEAH box helicase G-alpha PF00503.20 KXH28289.1 - 0.18 10.9 0.0 6.7 5.8 0.0 2.1 2 0 0 2 2 2 0 G-protein alpha subunit MMR_HSR1 PF01926.23 KXH28289.1 - 0.18 11.9 0.0 17 5.5 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF2057 PF09829.9 KXH28289.1 - 1.2 9.2 4.5 14 5.7 0.0 2.6 3 0 0 3 3 2 0 Uncharacterized protein conserved in bacteria (DUF2057) Zn_clus PF00172.18 KXH28290.1 - 5.9e-08 32.7 9.6 5.9e-08 32.7 9.6 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_17 PF00332.18 KXH28291.1 - 1e-06 28.6 0.7 2.2e-06 27.5 0.7 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 GTP1_OBG PF01018.22 KXH28292.1 - 2.1e-39 134.6 0.9 5.6e-30 104.0 1.8 2.8 3 0 0 3 3 3 2 GTP1/OBG MMR_HSR1 PF01926.23 KXH28292.1 - 6.1e-24 84.3 0.1 2e-23 82.6 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KXH28292.1 - 3e-08 33.3 0.0 1.2e-07 31.4 0.1 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B MeaB PF03308.16 KXH28292.1 - 0.0082 15.2 4.7 0.55 9.2 0.0 2.9 3 0 0 3 3 3 2 Methylmalonyl Co-A mutase-associated GTPase MeaB GTP_EFTU PF00009.27 KXH28292.1 - 0.014 15.0 0.0 1 8.8 0.0 2.6 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 KXH28292.1 - 0.018 15.6 0.6 0.046 14.2 0.0 1.9 2 0 0 2 2 2 0 ABC transporter Arf PF00025.21 KXH28292.1 - 0.13 11.7 0.0 0.8 9.1 0.0 2.0 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_23 PF13476.6 KXH28292.1 - 0.37 11.3 2.1 24 5.4 0.7 2.3 2 0 0 2 2 2 0 AAA domain Pes-10 PF07149.11 KXH28292.1 - 7.1 5.6 9.1 11 5.0 9.1 1.1 1 0 0 1 1 1 0 Pes-10 Atg14 PF10186.9 KXH28292.1 - 8.3 5.4 5.7 14 4.7 5.7 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 BCS1_N PF08740.11 KXH28298.1 - 4.7e-31 108.2 0.0 6.9e-31 107.7 0.0 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 KXH28298.1 - 1.4e-16 61.1 0.0 7.6e-16 58.7 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 KXH28298.1 - 0.016 14.6 0.0 0.046 13.1 0.0 1.7 1 1 1 2 2 2 0 KaiC DUF815 PF05673.13 KXH28298.1 - 0.02 14.1 0.0 0.042 13.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_25 PF13481.6 KXH28298.1 - 0.061 12.9 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KXH28298.1 - 0.11 12.9 0.1 0.29 11.5 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain RuvB_N PF05496.12 KXH28298.1 - 0.14 11.9 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KXH28298.1 - 0.15 12.1 0.0 0.33 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) PPV_E1_C PF00519.17 KXH28298.1 - 0.16 10.8 0.0 0.26 10.1 0.0 1.3 1 0 0 1 1 1 0 Papillomavirus helicase APH PF01636.23 KXH28300.1 - 2.3e-15 57.2 0.0 3.7e-15 56.5 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KXH28300.1 - 3.4e-05 23.5 0.0 4.9e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Zeta_toxin PF06414.12 KXH28301.1 - 2.9e-39 134.4 0.0 4e-39 134.0 0.0 1.1 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.6 KXH28301.1 - 0.0011 19.2 0.0 0.0022 18.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KXH28301.1 - 0.0023 18.4 0.1 0.0048 17.3 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain TniB PF05621.11 KXH28301.1 - 0.0098 15.3 0.0 0.056 12.8 0.0 2.0 2 0 0 2 2 2 1 Bacterial TniB protein AAA_22 PF13401.6 KXH28301.1 - 0.053 13.8 0.0 0.14 12.4 0.0 1.9 1 1 0 1 1 1 0 AAA domain DUF356 PF04009.12 KXH28301.1 - 0.056 13.7 0.1 0.12 12.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF356) TsaE PF02367.17 KXH28301.1 - 0.076 13.0 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activat PF00158.26 KXH28301.1 - 0.083 12.6 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_29 PF13555.6 KXH28301.1 - 0.094 12.5 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain TrwB_AAD_bind PF10412.9 KXH28301.1 - 0.11 11.4 0.0 0.19 10.6 0.0 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Flavodoxin_1 PF00258.25 KXH28348.1 - 9.5e-30 103.7 0.0 1.8e-29 102.7 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin FAD_binding_1 PF00667.20 KXH28348.1 - 8.7e-24 84.3 0.1 2.2e-22 79.7 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain NAD_binding_1 PF00175.21 KXH28348.1 - 2.6e-08 34.5 0.0 1.7e-05 25.4 0.0 2.8 2 1 1 3 3 3 2 Oxidoreductase NAD-binding domain Flavodoxin_3 PF12641.7 KXH28348.1 - 0.014 15.1 0.0 0.027 14.2 0.0 1.5 1 0 0 1 1 1 0 Flavodoxin domain Asp PF00026.23 KXH28349.1 - 7.8e-06 25.5 1.4 3.2e-05 23.5 1.4 1.9 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KXH28349.1 - 0.32 11.2 2.4 29 4.8 0.5 3.1 2 1 1 3 3 3 0 Xylanase inhibitor N-terminal F-box PF00646.33 KXH28352.1 - 2.1e-07 30.7 0.0 4.6e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KXH28352.1 - 2.5e-07 30.5 0.1 4.4e-07 29.7 0.1 1.4 1 0 0 1 1 1 1 F-box-like UIM PF02809.20 KXH28352.1 - 0.015 15.2 1.2 0.015 15.2 1.2 4.8 5 0 0 5 5 5 0 Ubiquitin interaction motif Fungal_trans_2 PF11951.8 KXH28353.1 - 2.1e-10 40.0 1.5 1.2e-09 37.4 1.5 2.2 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH28353.1 - 7.9e-07 29.1 10.2 1.4e-06 28.3 10.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PhoD_N PF16655.5 KXH28353.1 - 0.088 13.4 0.1 0.21 12.1 0.1 1.6 1 0 0 1 1 1 0 PhoD-like phosphatase, N-terminal domain Mob1_phocein PF03637.17 KXH28354.1 - 4.6e-22 78.8 0.2 7.6e-22 78.1 0.2 1.3 1 0 0 1 1 1 1 Mob1/phocein family CxC6 PF18721.1 KXH28354.1 - 0.16 12.3 3.6 0.35 11.2 3.6 1.6 1 0 0 1 1 1 0 CxC6 like cysteine cluster associated with KDZ transposases cobW PF02492.19 KXH28355.1 - 2e-47 161.1 0.3 2.7e-47 160.6 0.3 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 KXH28355.1 - 9.3e-06 25.6 0.2 0.16 11.9 0.0 2.6 2 1 0 2 2 2 2 RsgA GTPase CobW_C PF07683.14 KXH28355.1 - 0.00021 21.2 0.0 0.0004 20.3 0.0 1.5 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain AAA_16 PF13191.6 KXH28355.1 - 0.0061 17.0 0.0 0.039 14.3 0.0 2.2 2 1 1 3 3 3 1 AAA ATPase domain MMR_HSR1 PF01926.23 KXH28355.1 - 0.0083 16.2 0.0 0.018 15.1 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 KXH28355.1 - 0.0086 15.9 0.5 0.49 10.1 0.1 2.5 2 1 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_23 PF13476.6 KXH28355.1 - 0.01 16.4 0.1 0.023 15.2 0.1 1.6 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 KXH28355.1 - 0.017 14.1 0.7 2.9 6.8 0.1 2.9 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB GTP_EFTU PF00009.27 KXH28355.1 - 0.019 14.5 0.1 4.9 6.6 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Septin PF00735.18 KXH28355.1 - 0.027 13.7 0.7 5.7 6.1 0.0 2.5 2 1 0 2 2 2 0 Septin AAA_22 PF13401.6 KXH28355.1 - 0.029 14.6 0.5 0.35 11.1 0.0 2.4 3 0 0 3 3 3 0 AAA domain AAA_29 PF13555.6 KXH28355.1 - 0.047 13.4 0.2 0.13 12.0 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain TsaE PF02367.17 KXH28355.1 - 0.098 12.7 0.0 0.23 11.5 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 KXH28355.1 - 0.13 12.0 0.7 0.47 10.1 0.1 2.0 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KXH28355.1 - 0.14 12.7 0.8 0.66 10.5 0.1 2.3 3 0 0 3 3 2 0 ABC transporter NOT2_3_5 PF04153.18 KXH28356.1 - 8.5e-28 97.1 0.5 1.3e-27 96.5 0.5 1.3 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family GHMP_kinases_N PF00288.26 KXH28364.1 - 1.6e-15 57.0 3.2 4e-15 55.8 3.2 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KXH28364.1 - 0.0032 17.8 0.2 0.0089 16.4 0.1 1.9 2 0 0 2 2 2 1 GHMP kinases C terminal BST2 PF16716.5 KXH28364.1 - 0.08 13.5 0.1 0.16 12.6 0.1 1.4 1 0 0 1 1 1 0 Bone marrow stromal antigen 2 PPR_2 PF13041.6 KXH28365.1 - 1.9e-42 143.2 15.2 1.6e-08 34.6 0.0 14.7 11 3 5 16 16 16 7 PPR repeat family PPR_3 PF13812.6 KXH28365.1 - 1.9e-30 104.7 0.8 0.0025 17.9 0.0 10.4 7 2 3 11 11 11 7 Pentatricopeptide repeat domain PPR PF01535.20 KXH28365.1 - 6.1e-23 79.4 34.5 0.0012 19.0 0.1 14.5 18 0 0 18 18 18 7 PPR repeat PPR_1 PF12854.7 KXH28365.1 - 1.3e-19 69.6 0.3 1.4e-07 31.1 0.0 9.8 12 0 0 12 12 12 3 PPR repeat PPR_long PF17177.4 KXH28365.1 - 2.6e-16 59.6 16.0 6.2e-07 29.0 0.4 6.3 4 2 2 7 7 7 5 Pentacotripeptide-repeat region of PRORP RPM2 PF08579.11 KXH28365.1 - 3.2e-05 24.3 0.0 0.0016 18.8 0.0 3.4 4 0 0 4 4 4 1 Mitochondrial ribonuclease P subunit (RPM2) ATP13 PF12921.7 KXH28365.1 - 0.002 17.9 0.2 0.19 11.6 0.1 3.7 4 1 0 4 4 4 1 Mitochondrial ATPase expression TPR_7 PF13176.6 KXH28365.1 - 0.31 11.1 1.4 32 4.9 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat Aldedh PF00171.22 KXH28367.1 - 1.1e-131 439.5 0.0 1.4e-131 439.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KXH28367.1 - 0.0002 20.5 0.1 0.00061 18.9 0.1 1.7 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.11 KXH28367.1 - 0.055 12.9 0.0 6.2 6.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) RRM_1 PF00076.22 KXH28368.1 - 5.8e-08 32.4 0.0 7.1e-06 25.8 0.0 2.4 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nop14 PF04147.12 KXH28368.1 - 3.5 5.7 22.8 0.041 12.1 13.8 1.8 2 0 0 2 2 2 0 Nop14-like family AAR2 PF05282.11 KXH28368.1 - 8.6 5.6 6.7 0.65 9.3 0.8 1.7 1 1 0 2 2 2 0 AAR2 protein NMD3 PF04981.13 KXH28370.1 - 5.2e-78 261.9 4.1 7.1e-78 261.4 4.1 1.2 1 0 0 1 1 1 1 NMD3 family DUF35_N PF12172.8 KXH28370.1 - 0.084 12.8 5.7 0.96 9.4 0.0 2.8 3 0 0 3 3 3 0 Rubredoxin-like zinc ribbon domain (DUF35_N) HpcH_HpaI PF03328.14 KXH28371.1 - 4.9e-22 78.2 0.0 7.9e-22 77.5 0.0 1.3 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PK PF00224.21 KXH28371.1 - 0.15 10.9 0.0 0.24 10.2 0.0 1.2 1 0 0 1 1 1 0 Pyruvate kinase, barrel domain WD40 PF00400.32 KXH28372.1 - 3e-12 46.9 4.4 0.01 16.7 0.0 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXH28372.1 - 0.0005 20.3 0.8 1 9.7 0.0 4.5 5 0 0 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Kinase-like PF14531.6 KXH28372.1 - 0.1 11.9 0.0 1.4 8.1 0.0 2.3 3 0 0 3 3 3 0 Kinase-like MFS_1 PF07690.16 KXH28373.1 - 1.3e-37 129.6 47.9 1.3e-37 129.6 47.9 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KXH28373.1 - 7.8e-15 54.3 26.0 1.6e-14 53.3 26.0 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) ATP-synt_J PF04911.12 KXH28374.1 - 0.052 13.1 1.5 1.4 8.5 0.0 3.0 3 0 0 3 3 3 0 ATP synthase j chain FAD_binding_4 PF01565.23 KXH28375.1 - 1.3e-18 67.0 3.7 2.5e-18 66.2 2.3 2.0 2 0 0 2 2 2 1 FAD binding domain Rib_5-P_isom_A PF06026.14 KXH28376.1 - 1.8e-09 37.4 0.0 2.9e-09 36.8 0.0 1.4 1 1 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) Proteasome PF00227.26 KXH28377.1 - 1.4e-45 155.1 0.0 5.3e-30 104.3 0.0 2.2 1 1 1 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.9 KXH28377.1 - 4.7e-12 45.3 1.0 5.6e-12 45.1 0.0 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature CPSase_L_D2 PF02786.17 KXH28378.1 - 2.9e-81 272.0 0.4 4.5e-81 271.4 0.4 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 KXH28378.1 - 8e-69 231.4 0.0 1.4e-68 230.6 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain Biotin_carb_N PF00289.22 KXH28378.1 - 1e-38 132.3 0.1 2.1e-38 131.3 0.1 1.5 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KXH28378.1 - 2.5e-32 111.2 0.0 1e-31 109.2 0.0 2.1 2 0 0 2 2 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.19 KXH28378.1 - 1.2e-25 90.6 0.0 2.8e-25 89.4 0.0 1.6 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.22 KXH28378.1 - 4.4e-19 68.1 3.5 8.6e-19 67.2 1.8 2.4 2 0 0 2 2 2 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 KXH28378.1 - 1.3e-10 40.9 1.9 2.2e-06 27.4 0.1 3.3 2 1 1 3 3 3 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.13 KXH28378.1 - 7e-10 38.8 0.0 1.4e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KXH28378.1 - 7.9e-08 32.1 0.1 1.5e-07 31.1 0.1 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 KXH28378.1 - 7e-05 22.9 0.0 0.00018 21.6 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 KXH28378.1 - 0.00027 20.6 0.0 0.0013 18.4 0.0 1.9 1 1 0 1 1 1 1 RimK-like ATP-grasp domain HlyD_D23 PF16576.5 KXH28378.1 - 0.0009 18.5 0.1 0.17 11.1 0.0 2.4 1 1 1 2 2 2 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 KXH28378.1 - 0.0015 19.2 0.3 4 8.2 0.0 3.4 3 0 0 3 3 3 1 HlyD family secretion protein ATPgrasp_ST PF14397.6 KXH28378.1 - 0.0035 16.6 0.0 0.01 15.1 0.0 1.7 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp DUF2118 PF09891.9 KXH28378.1 - 0.0078 16.2 0.0 0.077 12.9 0.1 2.4 2 0 0 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2118) ATP-grasp_4 PF13535.6 KXH28378.1 - 0.0095 15.5 0.0 0.024 14.3 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 KXH28378.1 - 0.037 13.8 0.0 0.1 12.4 0.0 1.7 2 0 0 2 2 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATPgrasp_YheCD PF14398.6 KXH28378.1 - 0.064 12.5 0.0 2.7 7.2 0.0 2.2 2 0 0 2 2 2 0 YheC/D like ATP-grasp NQRA PF05896.11 KXH28378.1 - 0.074 12.5 0.2 0.13 11.7 0.2 1.3 1 0 0 1 1 1 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) GCV_H PF01597.19 KXH28378.1 - 0.17 11.8 1.0 0.59 10.0 0.2 2.3 2 0 0 2 2 2 0 Glycine cleavage H-protein RnfC_N PF13375.6 KXH28378.1 - 0.22 11.5 2.0 0.29 11.1 0.4 2.0 2 0 0 2 2 2 0 RnfC Barrel sandwich hybrid domain MPC PF03650.13 KXH28379.1 - 1.1e-35 122.1 0.0 1.3e-35 121.8 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers MtrG PF04210.13 KXH28379.1 - 0.12 12.3 0.2 0.18 11.6 0.2 1.3 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit G Sad1_UNC PF07738.13 KXH28418.1 - 5.8e-33 113.7 0.0 1.1e-32 112.8 0.0 1.5 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Dala_Dala_lig_C PF07478.13 KXH28418.1 - 0.12 11.9 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus DUF5344 PF17279.2 KXH28418.1 - 0.13 12.9 0.3 0.5 11.0 0.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5344) RRM_2 PF04059.12 KXH28419.1 - 2e-38 130.5 0.4 3.3e-38 129.8 0.4 1.3 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_1 PF00076.22 KXH28419.1 - 0.0014 18.4 0.0 0.26 11.1 0.0 2.7 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KXH28419.1 - 0.066 13.1 0.0 5 7.1 0.0 2.4 2 0 0 2 2 2 0 Occluded RNA-recognition motif Sec15 PF04091.12 KXH28420.1 - 1.4e-106 356.5 3.9 1.4e-106 356.5 3.9 2.1 2 0 0 2 2 2 1 Exocyst complex subunit Sec15-like DUF4201 PF13870.6 KXH28420.1 - 0.00057 19.7 4.5 0.00057 19.7 4.5 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4201) DUF3510 PF12022.8 KXH28420.1 - 0.037 14.4 1.6 2.3 8.6 0.1 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF3510) COG5 PF10392.9 KXH28420.1 - 0.092 12.9 5.3 0.62 10.2 3.7 2.8 2 0 0 2 2 2 0 Golgi transport complex subunit 5 BORCS8 PF10167.9 KXH28420.1 - 0.099 12.6 3.4 0.5 10.3 0.9 2.8 2 0 0 2 2 2 0 BLOC-1-related complex sub-unit 8 CBFD_NFYB_HMF PF00808.23 KXH28421.1 - 2.4e-19 69.4 0.5 3.7e-19 68.8 0.5 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KXH28421.1 - 3.5e-15 56.5 0.1 7.2e-15 55.5 0.1 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Pol_alpha_B_N PF08418.10 KXH28421.1 - 0.017 15.1 0.1 0.02 14.9 0.1 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal CENP-X PF09415.10 KXH28421.1 - 0.045 14.1 0.0 0.072 13.4 0.0 1.3 1 0 0 1 1 1 0 CENP-S associating Centromere protein X Asp-Al_Ex PF06826.12 KXH28438.1 - 0.064 13.1 0.1 0.099 12.5 0.1 1.2 1 0 0 1 1 1 0 Predicted Permease Membrane Region NAD_binding_10 PF13460.6 KXH28440.1 - 2.3e-21 76.5 0.1 3.1e-21 76.1 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KXH28440.1 - 8.3e-07 28.7 0.0 1.5e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXH28440.1 - 0.00057 19.4 0.0 0.00096 18.6 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KXH28440.1 - 0.036 13.2 0.0 0.1 11.7 0.0 1.6 1 1 0 1 1 1 0 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KXH28440.1 - 0.14 11.3 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DIOX_N PF14226.6 KXH28441.1 - 7.1e-05 23.5 0.2 0.00026 21.7 0.0 2.1 2 1 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KXH28441.1 - 0.00011 22.7 0.0 0.0002 21.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PIGA PF08288.12 KXH28442.1 - 2.7e-44 149.7 3.1 5e-44 148.8 1.0 2.2 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.20 KXH28442.1 - 1.1e-27 96.7 0.0 1.5e-27 96.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KXH28442.1 - 1.3e-23 83.9 1.8 2.3e-23 83.1 1.3 1.7 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 KXH28442.1 - 4.1e-23 82.3 0.1 8.9e-23 81.2 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KXH28442.1 - 1.8e-10 41.5 0.0 3.7e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.6 KXH28442.1 - 5.6e-07 29.7 0.1 1.1e-06 28.7 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.6 KXH28442.1 - 4.1e-06 27.1 0.0 2.5e-05 24.6 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferases group 1 DEAD PF00270.29 KXH28443.1 - 1.5e-32 112.7 0.0 1.2e-16 61.0 0.1 2.4 1 1 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 KXH28443.1 - 1.2e-19 70.7 0.0 3.8e-19 69.1 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXH28443.1 - 5.4e-08 33.0 0.9 1.9e-07 31.2 0.0 2.3 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DDHD PF02862.17 KXH28443.1 - 0.014 15.6 4.4 0.9 9.6 0.9 2.5 2 0 0 2 2 2 0 DDHD domain UvrD-helicase PF00580.21 KXH28443.1 - 0.023 14.2 0.0 0.023 14.2 0.0 2.3 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain BUD22 PF09073.10 KXH28443.1 - 0.43 9.9 45.8 0.065 12.6 9.2 2.5 2 0 0 2 2 2 0 BUD22 PAC4 PF16093.5 KXH28443.1 - 1.2 9.4 4.7 5.6 7.2 4.7 2.1 2 0 0 2 2 2 0 Proteasome assembly chaperone 4 FSA_C PF10479.9 KXH28443.1 - 3.8 5.5 8.5 5.9 4.9 8.5 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus RR_TM4-6 PF06459.12 KXH28443.1 - 5.9 6.6 29.1 0.22 11.3 18.3 2.6 3 0 0 3 3 3 0 Ryanodine Receptor TM 4-6 Toxin_18 PF08087.11 KXH28444.1 - 0.93 9.5 6.7 0.75 9.8 0.3 2.5 2 0 0 2 2 2 0 Conotoxin O-superfamily Acetyltransf_1 PF00583.25 KXH28445.1 - 3.4e-08 33.7 0.1 6.9e-08 32.7 0.1 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXH28445.1 - 1.6e-07 31.3 0.0 3.5e-07 30.2 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXH28445.1 - 3.9e-07 30.4 0.0 1e-06 29.0 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXH28445.1 - 7.3e-05 22.7 0.0 0.00014 21.8 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 KXH28445.1 - 0.00025 21.1 0.0 0.00046 20.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KXH28445.1 - 0.0079 16.3 0.0 0.019 15.1 0.0 1.6 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Thiolase_N PF00108.23 KXH28446.1 - 2.9e-16 59.6 0.3 2.3e-14 53.4 0.2 2.8 2 1 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KXH28446.1 - 7.6e-13 48.2 3.4 1.1e-12 47.7 0.6 2.7 2 1 1 3 3 3 1 Thiolase, C-terminal domain ACP_syn_III PF08545.10 KXH28446.1 - 5.4e-07 29.4 0.4 1.7e-05 24.6 0.1 2.5 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.26 KXH28446.1 - 2.3e-05 24.1 0.1 5.6e-05 22.9 0.0 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KXH28446.1 - 0.0018 18.3 0.1 0.13 12.3 0.0 3.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain SpoVAD PF07451.11 KXH28446.1 - 0.022 13.5 2.5 0.13 10.9 0.2 2.7 3 0 0 3 3 3 0 Stage V sporulation protein AD (SpoVAD) FAD_binding_3 PF01494.19 KXH28447.1 - 3e-23 82.6 0.1 1.3e-22 80.6 0.1 1.8 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KXH28447.1 - 2.7e-09 37.1 5.0 0.00019 21.1 1.2 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXH28447.1 - 2.8e-08 33.3 0.1 0.00041 19.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KXH28447.1 - 2.1e-07 30.3 0.0 6.6e-05 22.1 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox PF00070.27 KXH28447.1 - 4.4e-05 23.9 0.1 0.1 13.2 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXH28447.1 - 0.00091 19.4 0.1 0.0025 18.0 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KXH28447.1 - 0.0011 18.2 0.9 0.0018 17.4 0.2 1.7 2 0 0 2 2 2 1 FAD binding domain SE PF08491.10 KXH28447.1 - 0.0014 17.7 0.0 0.12 11.4 0.0 2.3 2 0 0 2 2 2 1 Squalene epoxidase HI0933_like PF03486.14 KXH28447.1 - 0.0022 16.8 0.3 0.59 8.8 0.4 2.1 2 0 0 2 2 2 2 HI0933-like protein Trp_halogenase PF04820.14 KXH28447.1 - 0.13 11.1 2.1 3.4 6.4 0.0 2.4 3 0 0 3 3 3 0 Tryptophan halogenase Complex1_LYR_2 PF13233.6 KXH28450.1 - 3.1e-18 66.3 0.0 4.3e-18 65.8 0.0 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 KXH28450.1 - 2.9e-10 40.0 0.0 6.8e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.6 KXH28450.1 - 0.1 13.2 0.0 0.17 12.5 0.0 1.4 1 0 0 1 1 1 0 Complex1_LYR-like HA2 PF04408.23 KXH28451.1 - 3.2e-17 62.8 1.5 9.5e-17 61.3 0.0 2.5 3 0 0 3 3 3 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KXH28451.1 - 5.6e-12 46.0 0.0 2e-11 44.2 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 KXH28451.1 - 1.2e-10 41.6 0.0 3.1e-10 40.3 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 KXH28451.1 - 5.8e-07 29.4 0.0 1.5e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KXH28451.1 - 0.003 17.8 0.2 0.0081 16.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KXH28451.1 - 0.016 14.9 0.0 0.039 13.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain T2SSE PF00437.20 KXH28451.1 - 0.025 13.7 0.0 0.048 12.7 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_7 PF12775.7 KXH28451.1 - 0.056 13.0 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_23 PF13476.6 KXH28451.1 - 0.076 13.5 0.9 4.1 7.9 0.0 2.8 3 0 0 3 3 3 0 AAA domain ABC_tran PF00005.27 KXH28451.1 - 0.077 13.5 0.0 0.3 11.6 0.0 2.0 1 0 0 1 1 1 0 ABC transporter FtsK_SpoIIIE PF01580.18 KXH28451.1 - 0.092 12.1 0.0 1.3 8.3 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family Clostridium_P47 PF06597.11 KXH28451.1 - 0.094 11.4 0.0 0.15 10.7 0.0 1.2 1 0 0 1 1 1 0 Clostridium P-47 protein DUF5089 PF17002.5 KXH28453.1 - 0.18 11.6 14.3 0.041 13.8 9.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF5089) GTP_EFTU PF00009.27 KXH28454.1 - 1.3e-09 37.9 0.0 4.6e-09 36.1 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 KXH28454.1 - 0.0071 16.8 0.1 0.019 15.4 0.1 1.7 1 0 0 1 1 1 1 AAA ATPase domain DUF5546 PF17700.1 KXH28454.1 - 0.052 13.9 0.1 0.19 12.1 0.1 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF5546) SRPRB PF09439.10 KXH28454.1 - 0.077 12.4 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit T2SSE PF00437.20 KXH28454.1 - 0.09 11.8 0.5 0.18 10.8 0.5 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.6 KXH28454.1 - 0.1 12.4 0.9 0.26 11.1 0.9 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Rab5ip PF07019.12 KXH28455.1 - 5e-29 100.7 9.7 6e-29 100.5 9.7 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) Vezatin PF12632.7 KXH28456.1 - 3.6e-78 262.8 0.1 8.2e-78 261.6 0.0 1.6 2 0 0 2 2 2 1 Mysoin-binding motif of peroxisomes MASE1 PF05231.14 KXH28456.1 - 0.081 12.1 2.8 0.12 11.5 2.8 1.2 1 0 0 1 1 1 0 MASE1 DUF4231 PF14015.6 KXH28456.1 - 0.096 13.2 3.1 0.22 12.0 1.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) PCNA_N PF00705.18 KXH28457.1 - 1.2e-53 180.1 3.3 1.2e-53 180.1 3.3 1.9 2 1 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 KXH28457.1 - 5.4e-50 168.8 0.0 1e-49 168.0 0.0 1.4 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.13 KXH28457.1 - 2.4e-09 37.0 0.0 2.9e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 Rad9 Rad1 PF02144.16 KXH28457.1 - 4.5e-06 25.9 0.4 0.0001 21.5 0.4 2.0 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Hus1 PF04005.12 KXH28457.1 - 0.00084 18.5 0.2 0.0063 15.7 0.0 2.1 2 1 0 2 2 2 1 Hus1-like protein AMA-1 PF02430.15 KXH28457.1 - 0.054 12.4 0.0 0.09 11.7 0.0 1.3 1 0 0 1 1 1 0 Apical membrane antigen 1 DNA_pol3_beta_3 PF02768.15 KXH28457.1 - 0.064 13.1 0.1 0.21 11.4 0.0 2.0 2 1 0 2 2 2 0 DNA polymerase III beta subunit, C-terminal domain Phos_pyr_kin PF08543.12 KXH28458.1 - 4e-11 42.8 0.0 8.4e-11 41.7 0.0 1.5 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 KXH28458.1 - 1.9e-07 30.7 0.6 1.3e-06 28.0 0.0 2.4 3 0 0 3 3 3 1 pfkB family carbohydrate kinase zf-AD PF07776.15 KXH28460.1 - 1.9 8.8 6.7 2.5 8.4 0.0 3.6 4 0 0 4 4 4 0 Zinc-finger associated domain (zf-AD) PALP PF00291.25 KXH28461.1 - 1.3e-38 133.1 0.1 1.7e-38 132.8 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme HDPD PF02924.14 KXH28461.1 - 0.037 14.1 0.6 0.068 13.3 0.0 1.7 2 0 0 2 2 2 0 Bacteriophage lambda head decoration protein D Peptidase_M13_N PF05649.13 KXH28463.1 - 0.049 13.3 0.0 0.056 13.1 0.0 1.1 1 0 0 1 1 1 0 Peptidase family M13 CD99L2 PF12301.8 KXH28463.1 - 0.24 11.7 2.0 0.36 11.1 2.0 1.4 1 1 0 1 1 1 0 CD99 antigen like protein 2 ADH_zinc_N PF00107.26 KXH28464.1 - 2.7e-16 59.7 1.1 4e-16 59.2 0.2 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXH28464.1 - 3.6e-13 49.3 1.1 3.6e-13 49.3 1.1 2.0 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 KXH28464.1 - 0.018 14.4 1.4 0.029 13.7 1.4 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.6 KXH28464.1 - 0.02 15.9 0.3 0.064 14.3 0.3 1.9 1 1 0 1 1 1 0 Zinc-binding dehydrogenase TrkA_N PF02254.18 KXH28464.1 - 0.036 14.3 0.3 0.071 13.4 0.3 1.5 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox_3 PF13738.6 KXH28464.1 - 0.15 11.3 0.3 0.24 10.6 0.3 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Fungal_trans PF04082.18 KXH28465.1 - 1.5e-34 119.3 0.1 2.7e-34 118.4 0.1 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Aminotran_5 PF00266.19 KXH28466.1 - 1.6e-31 109.6 0.0 6.6e-31 107.6 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 KXH28466.1 - 0.00037 19.8 0.0 0.0014 17.9 0.0 1.9 2 0 0 2 2 2 1 Aminotransferase class I and II AA_permease PF00324.21 KXH28467.1 - 2e-115 386.1 41.9 2.3e-115 385.9 41.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KXH28467.1 - 1.9e-30 106.1 45.3 2.3e-30 105.8 45.3 1.1 1 0 0 1 1 1 1 Amino acid permease Sugar_tr PF00083.24 KXH28468.1 - 3.2e-32 112.0 32.9 9e-17 61.1 12.0 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KXH28468.1 - 6.3e-14 51.7 54.0 7.2e-12 44.9 25.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily CVNH PF08881.10 KXH28469.1 - 7.4e-12 45.8 0.5 4.1e-11 43.5 0.4 1.9 1 1 0 1 1 1 1 CVNH domain 2OG-FeII_Oxy_3 PF13640.6 KXH28470.1 - 1.7e-08 35.2 0.0 3.7e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily p450 PF00067.22 KXH28471.1 - 5e-79 266.2 0.0 6.3e-79 265.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Phytase PF02333.15 KXH28473.1 - 1.1e-66 225.3 0.9 1.1e-66 225.3 0.9 1.7 2 0 0 2 2 2 1 Phytase EGF_2 PF07974.13 KXH28473.1 - 4.9e-06 26.8 33.7 0.0037 17.6 11.0 2.5 2 0 0 2 2 2 2 EGF-like domain RVT_1 PF00078.27 KXH28474.1 - 1.7e-05 24.5 0.0 4e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SYF2 PF08231.12 KXH28474.1 - 3.4 8.1 5.5 3.5e+02 1.5 5.5 2.6 1 1 0 1 1 1 0 SYF2 splicing factor MFS_1 PF07690.16 KXH28475.1 - 1.6e-22 79.9 56.4 4.4e-22 78.5 41.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PNTB_4TM PF12769.7 KXH28475.1 - 0.16 12.4 5.8 1 9.9 5.8 2.4 1 0 0 1 1 1 0 4TM region of pyridine nucleotide transhydrogenase, mitoch NmrA PF05368.13 KXH28476.1 - 2.1e-25 89.7 0.6 2.6e-25 89.4 0.6 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXH28476.1 - 5.2e-23 81.9 0.0 7.7e-23 81.3 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KXH28476.1 - 1.6e-09 37.6 0.0 6.2e-07 29.1 0.0 2.3 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 KXH28476.1 - 0.00014 22.1 1.0 0.0012 19.1 0.1 2.2 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 KXH28476.1 - 0.00094 19.6 0.4 0.0024 18.3 0.4 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KXH28476.1 - 0.0019 18.3 0.0 0.005 16.9 0.1 1.6 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase RmlD_sub_bind PF04321.17 KXH28476.1 - 0.0019 17.3 0.2 0.0044 16.2 0.1 1.6 2 0 0 2 2 2 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 KXH28476.1 - 0.0023 17.0 0.0 0.0039 16.2 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 KXH28476.1 - 0.0027 17.2 0.4 0.0052 16.3 0.4 1.5 1 0 0 1 1 1 1 short chain dehydrogenase GDP_Man_Dehyd PF16363.5 KXH28476.1 - 0.0039 16.7 0.0 0.088 12.2 0.0 2.0 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_7 PF13241.6 KXH28476.1 - 0.0044 17.4 0.3 0.0098 16.3 0.3 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding DapB_N PF01113.20 KXH28476.1 - 0.0059 16.7 0.2 0.012 15.7 0.2 1.6 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus CoA_binding_2 PF13380.6 KXH28476.1 - 0.034 14.6 0.2 0.078 13.5 0.2 1.6 1 1 0 1 1 1 0 CoA binding domain 3HCDH_N PF02737.18 KXH28476.1 - 0.046 13.6 0.5 0.093 12.6 0.5 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 KXH28476.1 - 0.082 12.2 0.5 0.23 10.8 0.2 2.0 2 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DFP PF04127.15 KXH28476.1 - 0.36 10.6 4.5 0.1 12.4 1.2 1.7 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein TFIIA PF03153.13 KXH28481.1 - 6.6 6.6 10.2 8.3 6.3 10.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FKBP_C PF00254.28 KXH28484.1 - 6.2e-22 77.7 0.0 9.3e-22 77.2 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase ThiF PF00899.21 KXH28485.1 - 1.5e-112 374.9 0.0 8.2e-76 254.6 0.0 2.5 2 1 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 KXH28485.1 - 7.1e-93 311.1 0.6 1.3e-92 310.2 0.6 1.5 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_FCCH PF16190.5 KXH28485.1 - 2.2e-31 107.9 0.1 7.1e-31 106.2 0.1 2.0 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_UFD PF09358.10 KXH28485.1 - 6.6e-29 100.5 0.1 1.7e-28 99.2 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin fold domain E1_4HB PF16191.5 KXH28485.1 - 2.5e-24 85.2 0.7 2.5e-24 85.2 0.7 1.9 2 0 0 2 2 2 1 Ubiquitin-activating enzyme E1 four-helix bundle GST_N_2 PF13409.6 KXH28485.1 - 4.6e-18 65.3 0.0 1.4e-17 63.8 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KXH28485.1 - 1.7e-13 50.4 0.0 5.5e-13 48.7 0.0 2.0 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KXH28485.1 - 7.1e-05 23.2 0.2 0.0023 18.3 0.2 2.5 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KXH28485.1 - 0.13 12.5 0.0 0.38 11.0 0.0 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 KXH28485.1 - 0.17 12.5 0.0 0.36 11.4 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Chitin_synth_2 PF03142.15 KXH28486.1 - 1e-247 822.9 2.2 1.5e-247 822.4 2.2 1.2 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 KXH28486.1 - 3.3e-75 253.7 0.0 9.9e-74 248.8 0.0 2.1 1 1 0 1 1 1 1 Myosin head (motor domain) DEK_C PF08766.11 KXH28486.1 - 5e-17 61.6 0.0 2.4e-16 59.4 0.1 2.2 2 0 0 2 2 2 1 DEK C terminal domain Cyt-b5 PF00173.28 KXH28486.1 - 1.7e-14 53.7 0.4 2.2e-11 43.7 0.1 3.4 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain Glyco_trans_2_3 PF13632.6 KXH28486.1 - 4.6e-11 43.0 4.6 4.6e-11 43.0 4.6 2.0 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KXH28486.1 - 1.7e-09 38.0 0.1 2.9e-08 33.9 0.1 2.4 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KXH28486.1 - 1.2e-05 25.1 0.0 0.017 15.0 0.0 2.6 2 0 0 2 2 2 2 Glycosyl transferase family 2 AAA_16 PF13191.6 KXH28486.1 - 0.037 14.4 0.6 0.18 12.2 0.1 2.4 2 0 0 2 2 2 0 AAA ATPase domain RsgA_GTPase PF03193.16 KXH28486.1 - 0.057 13.3 0.0 0.16 11.9 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 KXH28486.1 - 0.062 13.0 0.1 0.17 11.6 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KXH28486.1 - 0.078 13.1 0.1 3.6 7.7 0.1 3.0 2 1 0 2 2 2 0 50S ribosome-binding GTPase ABC_tran PF00005.27 KXH28486.1 - 0.11 13.0 2.3 0.19 12.2 0.1 2.3 2 0 0 2 2 2 0 ABC transporter RNA_helicase PF00910.22 KXH28486.1 - 0.18 12.2 0.2 1 9.8 0.0 2.4 2 0 0 2 2 2 0 RNA helicase Chitin_synth_2 PF03142.15 KXH28487.1 - 2.6e-228 758.9 0.1 3.6e-228 758.5 0.1 1.2 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.6 KXH28487.1 - 5e-16 59.2 2.1 1.1e-15 58.0 2.1 1.6 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Cyt-b5 PF00173.28 KXH28487.1 - 1.5e-14 53.9 0.6 3.7e-09 36.6 0.0 3.0 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain DEK_C PF08766.11 KXH28487.1 - 2e-14 53.3 0.2 1.1e-13 50.8 0.3 2.1 2 0 0 2 2 2 1 DEK C terminal domain Glyco_tranf_2_3 PF13641.6 KXH28487.1 - 8.2e-11 42.2 0.0 3.6e-10 40.1 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Myosin_head PF00063.21 KXH28487.1 - 3e-07 29.1 0.0 1.4e-06 26.8 0.0 1.8 1 1 0 1 1 1 1 Myosin head (motor domain) Glyco_transf_21 PF13506.6 KXH28487.1 - 0.00021 20.8 0.0 0.0019 17.7 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 KXH28487.1 - 0.0012 18.6 0.0 0.23 11.2 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 BCDHK_Adom3 PF10436.9 KXH28488.1 - 2.1e-48 164.2 0.0 2.9e-48 163.8 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KXH28488.1 - 1.7e-11 44.6 0.0 7.4e-11 42.5 0.0 2.0 2 1 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 KXH28488.1 - 0.18 11.8 0.0 0.37 10.8 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Inhibitor_I9 PF05922.16 KXH28489.1 - 7.6e-14 52.1 0.6 1.3e-13 51.4 0.6 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 Gp_dh_C PF02800.20 KXH28489.1 - 0.038 13.6 0.2 0.047 13.3 0.2 1.1 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain RIBIOP_C PF04950.12 KXH28490.1 - 4.6e-94 315.1 0.1 4.6e-94 315.1 0.1 2.0 2 0 0 2 2 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 KXH28490.1 - 4.3e-27 94.0 0.0 1.7e-26 92.1 0.0 2.1 1 0 0 1 1 1 1 AARP2CN (NUC121) domain AAA_22 PF13401.6 KXH28490.1 - 4.3e-05 23.8 0.1 0.00013 22.2 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.6 KXH28490.1 - 0.0001 22.7 0.0 0.00041 20.8 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 KXH28490.1 - 0.00031 21.2 0.4 0.0032 18.0 0.0 2.6 2 0 0 2 2 2 1 ABC transporter AAA_33 PF13671.6 KXH28490.1 - 0.00046 20.4 3.7 0.0015 18.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 KXH28490.1 - 0.00052 20.1 0.0 0.0019 18.3 0.0 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA PF00004.29 KXH28490.1 - 0.00055 20.4 0.0 0.0015 19.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 KXH28490.1 - 0.00078 19.4 0.0 0.0019 18.2 0.0 1.7 1 1 0 1 1 1 1 NACHT domain AAA_19 PF13245.6 KXH28490.1 - 0.0023 18.3 0.2 0.01 16.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain GTP_EFTU PF00009.27 KXH28490.1 - 0.0023 17.5 1.5 0.3 10.6 0.0 2.9 2 1 1 3 3 2 1 Elongation factor Tu GTP binding domain RNA_helicase PF00910.22 KXH28490.1 - 0.0074 16.7 0.0 0.022 15.1 0.0 1.9 1 0 0 1 1 1 1 RNA helicase PduV-EutP PF10662.9 KXH28490.1 - 0.011 15.4 0.0 0.054 13.3 0.0 2.0 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_30 PF13604.6 KXH28490.1 - 0.012 15.3 0.7 0.032 13.9 0.0 2.0 2 0 0 2 2 1 0 AAA domain NB-ARC PF00931.22 KXH28490.1 - 0.013 14.7 0.0 0.032 13.4 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_14 PF13173.6 KXH28490.1 - 0.013 15.5 0.0 0.054 13.5 0.0 2.0 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KXH28490.1 - 0.015 15.2 0.0 0.14 12.1 0.0 2.6 3 0 0 3 3 2 0 RsgA GTPase cobW PF02492.19 KXH28490.1 - 0.015 14.9 0.1 0.034 13.7 0.1 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.14 KXH28490.1 - 0.019 14.9 1.6 0.2 11.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Ploopntkinase3 PF18751.1 KXH28490.1 - 0.019 14.8 0.0 0.044 13.7 0.0 1.5 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 AAA_28 PF13521.6 KXH28490.1 - 0.02 15.1 1.2 0.047 13.9 0.0 2.3 2 0 0 2 2 1 0 AAA domain NTPase_1 PF03266.15 KXH28490.1 - 0.029 14.3 0.2 0.063 13.2 0.2 1.6 1 0 0 1 1 1 0 NTPase Roc PF08477.13 KXH28490.1 - 0.037 14.2 0.0 0.11 12.7 0.0 1.8 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase MobB PF03205.14 KXH28490.1 - 0.038 13.9 0.9 0.54 10.2 0.1 2.7 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.6 KXH28490.1 - 0.042 14.4 0.0 0.042 14.4 0.0 3.8 4 1 0 4 4 2 0 AAA domain AAA_7 PF12775.7 KXH28490.1 - 0.066 12.7 0.1 0.22 11.0 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_25 PF13481.6 KXH28490.1 - 0.1 12.2 0.0 0.24 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain WD40 PF00400.32 KXH28491.1 - 3.3e-11 43.6 4.6 0.00068 20.4 0.0 4.3 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXH28491.1 - 4.5e-05 23.7 0.2 0.44 10.9 0.0 3.5 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KXH28491.1 - 6.7e-05 22.0 0.1 0.28 10.1 0.0 3.0 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Mo-co_dimer PF03404.16 KXH28491.1 - 0.011 15.7 0.1 0.019 15.0 0.1 1.3 1 0 0 1 1 1 0 Mo-co oxidoreductase dimerisation domain TFIIIC_delta PF12657.7 KXH28491.1 - 0.034 14.1 0.0 0.16 11.9 0.0 2.0 2 0 0 2 2 2 0 Transcription factor IIIC subunit delta N-term HemX PF04375.14 KXH28491.1 - 0.052 12.8 1.1 0.078 12.3 1.1 1.1 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase MFS_1 PF07690.16 KXH28492.1 - 1.2e-40 139.6 62.7 2.5e-40 138.5 58.3 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily Zn_clus PF00172.18 KXH28492.1 - 4.6e-05 23.4 1.3 8.7e-05 22.6 1.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KXH28492.1 - 6.1e-05 22.0 0.6 9.7e-05 21.3 0.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.18 KXH28493.1 - 9.7e-16 57.6 0.0 1.4e-15 57.0 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH28493.1 - 1e-08 35.1 11.5 1.6e-08 34.5 11.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_15 PF00723.21 KXH28494.1 - 4.2e-83 279.6 0.1 5.1e-83 279.3 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.19 KXH28494.1 - 2.6e-21 75.3 0.2 7.3e-21 73.9 0.0 1.9 2 0 0 2 2 2 1 Starch binding domain p450 PF00067.22 KXH28495.1 - 1.3e-47 162.7 0.0 1.6e-47 162.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_23 PF13489.6 KXH28496.1 - 1.5e-12 47.7 0.1 2.8e-12 46.8 0.1 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH28496.1 - 0.00017 22.2 0.0 0.0013 19.4 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH28496.1 - 0.00028 21.6 0.0 0.0029 18.3 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH28496.1 - 0.00081 19.2 0.0 0.0084 15.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH28496.1 - 0.019 15.6 0.0 0.062 13.9 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.6 KXH28497.1 - 2.5e-15 56.7 0.0 3.9e-15 56.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH28497.1 - 5.5e-10 39.8 0.0 1.3e-09 38.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH28497.1 - 2.3e-09 37.9 0.0 1.4e-08 35.4 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH28497.1 - 1.6e-08 35.0 0.0 3e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH28497.1 - 3.2e-08 33.5 0.0 7.9e-08 32.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KXH28497.1 - 0.00032 20.2 0.1 0.00089 18.8 0.0 1.7 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_2 PF00891.18 KXH28497.1 - 0.0058 15.9 0.0 0.0085 15.4 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain PrmA PF06325.13 KXH28497.1 - 0.0076 15.7 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KXH28497.1 - 0.0098 15.5 0.0 0.02 14.5 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase small domain Ubie_methyltran PF01209.18 KXH28497.1 - 0.011 15.1 0.0 0.2 11.0 0.0 2.4 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family Met_10 PF02475.16 KXH28497.1 - 0.12 12.2 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein CMAS PF02353.20 KXH28497.1 - 0.2 10.9 0.0 0.33 10.2 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Calpain_inhib PF00748.19 KXH28497.1 - 0.2 12.1 0.0 0.38 11.3 0.0 1.4 1 0 0 1 1 1 0 Calpain inhibitor CDC45 PF02724.14 KXH28498.1 - 1.2e-254 846.5 0.0 2.2e-254 845.6 0.0 1.8 1 1 0 1 1 1 1 CDC45-like protein BUD22 PF09073.10 KXH28498.1 - 3.1 7.1 33.5 2.9 7.2 14.5 2.1 2 0 0 2 2 2 0 BUD22 Hemerythrin PF01814.23 KXH28499.1 - 9.7e-10 39.2 0.5 1.3e-09 38.7 0.5 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain EF-hand_7 PF13499.6 KXH28500.1 - 1.7e-25 89.3 8.9 1.4e-16 60.7 1.2 3.0 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 KXH28500.1 - 6.8e-25 84.8 4.9 3.8e-06 26.4 0.1 5.2 5 0 0 5 5 5 4 EF-hand domain EF-hand_1 PF00036.32 KXH28500.1 - 2.8e-24 82.8 13.8 3.2e-08 32.5 0.2 4.8 5 0 0 5 5 5 3 EF hand EF-hand_5 PF13202.6 KXH28500.1 - 2.5e-17 61.5 13.8 3.8e-05 23.0 0.1 4.6 5 0 0 5 5 5 4 EF hand EF-hand_8 PF13833.6 KXH28500.1 - 6.8e-15 54.7 12.2 3e-05 23.8 1.0 3.9 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.7 KXH28500.1 - 4.1e-09 36.3 8.1 0.0046 16.9 0.2 4.0 1 1 2 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 KXH28500.1 - 8.3e-05 22.8 0.6 0.0086 16.4 0.1 2.9 2 1 1 3 3 3 2 EF-hand domain SPARC_Ca_bdg PF10591.9 KXH28500.1 - 0.00097 19.4 3.4 0.96 9.8 0.4 3.1 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region DUF1679 PF07914.11 KXH28500.1 - 0.027 13.4 0.4 2.1 7.1 0.1 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF1679) EF-hand_10 PF14788.6 KXH28500.1 - 0.08 12.8 5.1 0.27 11.1 0.0 3.6 5 0 0 5 5 5 0 EF hand Staphylokinase PF02821.16 KXH28500.1 - 0.085 13.3 0.0 5.4 7.5 0.0 2.5 1 1 0 1 1 1 0 Staphylokinase/Streptokinase family EF-hand_14 PF17959.1 KXH28500.1 - 0.12 12.7 2.9 6.8 7.1 0.0 3.6 3 1 0 3 3 3 0 EF-hand domain AMP-binding PF00501.28 KXH28501.1 - 1e-87 294.5 0.1 1.5e-87 293.9 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme CdhD PF03599.16 KXH28501.1 - 0.043 12.5 0.0 0.072 11.8 0.0 1.2 1 0 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase delta subunit 5-FTHF_cyc-lig PF01812.20 KXH28502.1 - 1.8e-28 99.7 0.0 2.4e-28 99.3 0.0 1.2 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family LSM PF01423.22 KXH28503.1 - 7.5e-16 57.6 0.1 8.9e-16 57.3 0.1 1.1 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 KXH28503.1 - 0.002 17.7 0.2 0.003 17.2 0.2 1.3 1 0 0 1 1 1 1 Hfq protein PhnA PF03831.14 KXH28503.1 - 0.085 12.7 0.1 2.3 8.2 0.0 2.2 2 0 0 2 2 2 0 PhnA domain Xpo1 PF08389.12 KXH28504.1 - 2.5e-29 102.3 1.0 1.4e-27 96.6 0.1 3.9 2 1 1 3 3 3 1 Exportin 1-like protein IBN_N PF03810.19 KXH28504.1 - 3.9e-07 29.9 0.0 3.2e-06 26.9 0.1 2.6 2 0 0 2 2 2 1 Importin-beta N-terminal domain Importin_rep_3 PF18806.1 KXH28504.1 - 0.0011 19.0 0.0 0.17 12.0 0.0 3.9 3 1 0 3 3 3 1 Importin 13 repeat Adaptin_N PF01602.20 KXH28504.1 - 0.027 13.0 1.4 1.7 7.1 0.2 2.4 2 0 0 2 2 2 0 Adaptin N terminal region HEAT_EZ PF13513.6 KXH28504.1 - 0.034 14.7 1.5 3.1 8.4 0.0 4.7 4 0 0 4 4 4 0 HEAT-like repeat Pox_F16 PF04708.12 KXH28504.1 - 0.049 13.1 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Poxvirus F16 protein UME PF08064.13 KXH28504.1 - 0.45 10.4 6.4 2.9 7.8 0.0 4.9 6 0 0 6 6 6 0 UME (NUC010) domain ECM11 PF15463.6 KXH28505.1 - 9.8e-45 152.4 5.2 2.3e-44 151.2 5.2 1.7 1 0 0 1 1 1 1 Extracellular mutant protein 11 NACHT PF05729.12 KXH28506.1 - 0.0002 21.3 0.0 0.0004 20.4 0.0 1.4 1 0 0 1 1 1 1 NACHT domain SRP54 PF00448.22 KXH28506.1 - 0.00022 20.9 0.0 0.00032 20.4 0.0 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_18 PF13238.6 KXH28506.1 - 0.00032 21.2 0.0 0.00071 20.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain MeaB PF03308.16 KXH28506.1 - 0.00049 19.2 0.0 0.00078 18.5 0.0 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 KXH28506.1 - 0.0013 19.2 0.1 0.0025 18.2 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain ArsA_ATPase PF02374.15 KXH28506.1 - 0.0059 15.8 0.0 0.0098 15.1 0.0 1.2 1 0 0 1 1 1 1 Anion-transporting ATPase KAP_NTPase PF07693.14 KXH28506.1 - 0.0075 15.5 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 KAP family P-loop domain AAA_14 PF13173.6 KXH28506.1 - 0.008 16.2 0.0 0.016 15.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KXH28506.1 - 0.0085 16.5 0.0 0.022 15.2 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 KXH28506.1 - 0.013 15.5 0.2 0.039 14.0 0.1 1.7 1 1 1 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE CBP_BcsQ PF06564.12 KXH28506.1 - 0.014 14.8 0.2 0.053 13.0 0.0 2.0 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsQ PRK PF00485.18 KXH28506.1 - 0.025 14.3 0.0 0.14 11.9 0.0 1.9 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Zeta_toxin PF06414.12 KXH28506.1 - 0.026 13.8 0.0 0.043 13.1 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin NB-ARC PF00931.22 KXH28506.1 - 0.031 13.5 0.0 0.087 12.0 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain APS_kinase PF01583.20 KXH28506.1 - 0.034 14.0 0.0 0.12 12.3 0.0 1.8 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_33 PF13671.6 KXH28506.1 - 0.034 14.3 0.0 0.063 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KXH28506.1 - 0.049 13.5 0.1 0.08 12.8 0.1 1.3 1 0 0 1 1 1 0 NTPase AAA_31 PF13614.6 KXH28506.1 - 0.049 13.5 0.0 0.079 12.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.17 KXH28506.1 - 0.056 13.1 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Thymidylate kinase CbiA PF01656.23 KXH28506.1 - 0.065 13.3 0.0 0.071 13.2 0.0 1.3 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_28 PF13521.6 KXH28506.1 - 0.075 13.3 0.0 0.17 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain CPT PF07931.12 KXH28506.1 - 0.084 12.7 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_30 PF13604.6 KXH28506.1 - 0.084 12.6 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KXH28506.1 - 0.099 12.9 0.0 0.17 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KXH28506.1 - 0.1 12.3 0.0 0.24 11.1 0.0 1.5 1 1 0 1 1 1 0 IstB-like ATP binding protein ATP_bind_1 PF03029.17 KXH28506.1 - 0.14 12.0 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein adh_short PF00106.25 KXH28507.1 - 3.7e-85 284.3 10.9 2.9e-44 150.9 0.7 2.7 3 0 0 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXH28507.1 - 4.2e-66 222.9 5.4 1.7e-34 119.4 0.4 2.4 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase MaoC_dehydratas PF01575.19 KXH28507.1 - 4.6e-33 113.4 0.0 9.7e-33 112.3 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain KR PF08659.10 KXH28507.1 - 1.6e-30 106.3 2.6 3e-14 53.4 0.1 2.3 2 0 0 2 2 2 2 KR domain THF_DHG_CYH_C PF02882.19 KXH28507.1 - 4.2e-05 22.9 1.1 0.005 16.2 0.4 2.5 2 0 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.21 KXH28507.1 - 0.0074 15.8 4.4 0.038 13.4 0.1 2.9 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family SoxE PF06525.11 KXH28507.1 - 0.035 13.6 0.1 4.7 6.7 0.0 2.8 2 0 0 2 2 2 0 Sulfocyanin (SoxE) domain MaoC_dehydrat_N PF13452.6 KXH28507.1 - 0.06 13.5 0.0 5.8 7.0 0.0 3.0 3 0 0 3 3 3 0 N-terminal half of MaoC dehydratase FAM25 PF15825.5 KXH28507.1 - 2.6 8.5 11.6 3.4 8.1 0.7 3.4 3 0 0 3 3 3 0 FAM25 family IBR PF01485.21 KXH28508.1 - 1.4e-05 25.2 5.4 1.4e-05 25.2 5.4 4.6 4 1 0 4 4 4 2 IBR domain, a half RING-finger domain adh_short PF00106.25 KXH28509.1 - 4.6e-50 169.8 0.1 6.1e-50 169.4 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXH28509.1 - 1.1e-32 113.5 0.0 1.3e-32 113.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH28509.1 - 5.6e-14 52.5 0.0 1.1e-13 51.5 0.0 1.5 1 1 1 2 2 2 1 KR domain Sacchrp_dh_NADP PF03435.18 KXH28509.1 - 0.0017 18.6 0.0 0.0035 17.6 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Polysacc_synt_2 PF02719.15 KXH28509.1 - 0.0033 16.6 0.3 0.008 15.3 0.2 1.6 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein RsgA_GTPase PF03193.16 KXH28509.1 - 0.064 13.2 1.0 2.7 7.9 0.3 2.3 1 1 1 2 2 2 0 RsgA GTPase MFS_1 PF07690.16 KXH28510.1 - 1.6e-41 142.4 44.7 2.4e-40 138.6 44.1 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH28510.1 - 6e-15 55.1 7.5 6e-15 55.1 7.5 2.4 3 0 0 3 3 3 1 Sugar (and other) transporter OATP PF03137.20 KXH28510.1 - 0.082 11.2 14.1 0.0047 15.3 6.0 2.3 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family ThiF PF00899.21 KXH28511.1 - 7.4e-19 68.1 0.0 1.8e-18 66.8 0.0 1.6 1 1 0 1 1 1 1 ThiF family E1_4HB PF16191.5 KXH28511.1 - 0.12 12.6 0.0 6.1 7.1 0.0 2.6 2 0 0 2 2 2 0 Ubiquitin-activating enzyme E1 four-helix bundle Fungal_trans PF04082.18 KXH28512.1 - 1.3e-23 83.4 0.0 2.3e-23 82.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH28512.1 - 3.5e-07 30.2 12.6 6.2e-07 29.4 12.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Haem_oxygenas_2 PF14518.6 KXH28512.1 - 0.056 13.2 0.2 0.11 12.3 0.2 1.4 1 0 0 1 1 1 0 Iron-containing redox enzyme zf-RING_5 PF14634.6 KXH28513.1 - 3.1e-06 27.0 11.6 3.1e-06 27.0 11.6 1.7 2 0 0 2 2 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KXH28513.1 - 0.00058 19.7 7.4 0.0012 18.7 7.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXH28513.1 - 0.0016 18.7 7.3 0.0036 17.6 7.3 1.6 1 0 0 1 1 1 1 Ring finger domain ApoLp-III PF07464.11 KXH28513.1 - 0.0058 16.7 1.0 0.0093 16.1 1.0 1.3 1 0 0 1 1 1 1 Apolipophorin-III precursor (apoLp-III) DUF4201 PF13870.6 KXH28513.1 - 0.0094 15.7 1.7 0.02 14.6 1.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) zf-RING_UBOX PF13445.6 KXH28513.1 - 0.01 15.8 1.4 0.01 15.8 1.4 2.2 1 1 1 2 2 2 0 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KXH28513.1 - 0.014 15.2 8.7 0.04 13.8 8.7 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF948 PF06103.11 KXH28513.1 - 0.018 15.3 0.3 0.032 14.5 0.3 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF4665 PF15679.5 KXH28513.1 - 0.027 15.1 0.4 0.062 13.9 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4665) zf-C3HC4_3 PF13920.6 KXH28513.1 - 0.05 13.5 10.2 0.11 12.4 10.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KXH28513.1 - 0.051 13.5 8.8 0.091 12.6 8.8 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Mito_carr PF00153.27 KXH28513.1 - 0.061 13.2 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial carrier protein Syntaxin_2 PF14523.6 KXH28513.1 - 0.076 13.4 4.3 0.15 12.4 4.3 1.5 1 0 0 1 1 1 0 Syntaxin-like protein YscO PF07321.12 KXH28513.1 - 0.17 11.8 4.5 0.43 10.5 4.5 1.6 1 0 0 1 1 1 0 Type III secretion protein YscO NYD-SP28 PF14772.6 KXH28513.1 - 0.63 10.1 5.1 0.6 10.2 1.6 2.3 2 0 0 2 2 2 0 Sperm tail Bap31_Bap29_C PF18035.1 KXH28513.1 - 0.66 10.0 3.8 1.4 9.0 3.8 1.6 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain Mod_r PF07200.13 KXH28513.1 - 1.7 8.7 8.0 14 5.8 8.2 2.1 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein OmpH PF03938.14 KXH28513.1 - 9.7 6.5 11.2 1.2 9.5 6.8 1.7 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) GDA1_CD39 PF01150.17 KXH28514.1 - 2.2e-108 362.6 0.0 3.2e-108 362.1 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family DUF775 PF05603.12 KXH28515.1 - 2.2e-60 203.6 0.1 2.5e-60 203.4 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF775) NUDIX PF00293.28 KXH28516.1 - 6.5e-11 42.4 0.1 1.2e-10 41.6 0.1 1.4 1 0 0 1 1 1 1 NUDIX domain DUF4743 PF15916.5 KXH28516.1 - 1.1e-10 41.6 0.0 1.8e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4743) RNA_pol_Rpb8 PF03870.15 KXH28517.1 - 2.9e-47 160.3 0.2 3.3e-47 160.2 0.2 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 RNA_pol_RpbG PF16992.5 KXH28517.1 - 7.6e-05 22.8 0.3 0.021 14.9 0.1 2.1 1 1 1 2 2 2 2 DNA-directed RNA polymerase, subunit G NB-ARC PF00931.22 KXH28517.1 - 0.088 12.0 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain tRNA_int_endo PF01974.17 KXH28518.1 - 2.5e-14 53.1 0.0 4.6e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain zf-C3HC4_3 PF13920.6 KXH28519.1 - 4.8e-09 35.9 12.5 7.9e-09 35.2 12.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KXH28519.1 - 0.04 13.8 13.0 0.067 13.1 13.0 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 RNase_PH PF01138.21 KXH28520.1 - 1e-27 97.2 0.1 1.9e-27 96.3 0.0 1.5 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 Anp1 PF03452.14 KXH28521.1 - 2.7e-113 377.8 0.6 8.7e-113 376.1 0.0 1.9 2 0 0 2 2 2 1 Anp1 Smg8_Smg9 PF10220.9 KXH28521.1 - 0.71 8.1 10.6 0.97 7.7 10.6 1.1 1 0 0 1 1 1 0 Smg8_Smg9 Sec7 PF01369.20 KXH28522.1 - 2e-65 219.9 0.0 4.1e-65 218.9 0.0 1.5 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 KXH28522.1 - 6.1e-16 58.7 0.1 8.6e-15 55.0 0.0 2.9 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DCB PF16213.5 KXH28522.1 - 0.017 14.8 0.1 0.13 12.0 0.0 2.4 2 0 0 2 2 2 0 Dimerisation and cyclophilin-binding domain of Mon2 RRM_1 PF00076.22 KXH28523.1 - 3.1e-25 87.8 1.1 4.2e-12 45.7 0.5 2.5 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KXH28523.1 - 1.2e-06 28.1 0.0 3.9e-05 23.2 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1866 PF08952.11 KXH28523.1 - 0.0012 18.7 0.0 0.041 13.7 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1866) RRM_occluded PF16842.5 KXH28523.1 - 0.013 15.3 0.0 4.6 7.2 0.0 2.3 2 0 0 2 2 2 0 Occluded RNA-recognition motif DUF4523 PF15023.6 KXH28523.1 - 0.11 12.4 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4523) ATP-synt_D PF01813.17 KXH28524.1 - 7.8e-71 238.0 0.9 9.5e-71 237.7 0.9 1.1 1 0 0 1 1 1 1 ATP synthase subunit D CobA_CobO_BtuR PF02572.15 KXH28524.1 - 0.31 11.3 2.7 1 9.6 0.1 2.3 2 1 1 3 3 3 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP DUF5446 PF17522.2 KXH28524.1 - 0.68 10.1 2.4 0.8 9.9 0.7 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5446) TPR_14 PF13428.6 KXH28525.1 - 8.7e-13 47.9 21.8 3.2 8.8 0.0 11.8 10 2 2 12 12 12 3 Tetratricopeptide repeat Suf PF05843.14 KXH28525.1 - 4.7e-11 43.2 9.7 0.031 14.3 0.0 6.1 4 1 1 6 6 6 3 Suppressor of forked protein (Suf) TPR_15 PF13429.6 KXH28525.1 - 1.2e-07 31.3 2.8 9.7e-05 21.7 0.5 4.1 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 KXH28525.1 - 1.4e-06 28.1 2.9 0.14 12.4 0.0 6.1 6 0 0 6 6 5 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 KXH28525.1 - 6.5e-06 26.1 10.0 0.23 11.4 0.1 6.5 7 0 0 7 7 7 3 Mad3/BUB1 homology region 1 TPR_12 PF13424.6 KXH28525.1 - 2.8e-05 24.3 3.7 3.8 7.9 0.0 6.7 7 0 0 7 7 7 1 Tetratricopeptide repeat RPN7 PF10602.9 KXH28525.1 - 0.00043 20.0 0.9 0.01 15.6 0.4 3.4 2 2 0 2 2 2 1 26S proteasome subunit RPN7 TPR_2 PF07719.17 KXH28525.1 - 0.0032 17.5 15.1 1.9 8.8 0.0 7.3 9 0 0 9 9 9 1 Tetratricopeptide repeat NRDE-2 PF08424.10 KXH28525.1 - 0.013 14.6 15.1 0.048 12.8 0.1 6.4 4 2 5 9 9 9 0 NRDE-2, necessary for RNA interference TPR_4 PF07721.14 KXH28525.1 - 0.074 13.7 0.4 3.1 8.7 0.1 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat MIT PF04212.18 KXH28525.1 - 0.18 11.9 0.8 1.2 9.2 0.1 2.8 3 0 0 3 3 2 0 MIT (microtubule interacting and transport) domain TPR_10 PF13374.6 KXH28525.1 - 0.25 11.3 11.6 23 5.0 0.0 6.4 6 0 0 6 6 6 0 Tetratricopeptide repeat LEM PF03020.15 KXH28525.1 - 1.1 8.9 2.5 27 4.4 0.0 3.1 3 0 0 3 3 3 0 LEM domain Egh16-like PF11327.8 KXH28527.1 - 1.7e-52 178.5 9.5 2.1e-52 178.2 9.5 1.1 1 0 0 1 1 1 1 Egh16-like virulence factor PolyA_pol PF01743.20 KXH28529.1 - 8e-27 94.2 0.1 1.6e-26 93.2 0.1 1.5 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 KXH28529.1 - 5.5e-06 26.1 0.0 1.2e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A tRNA_NucTran2_2 PF13735.6 KXH28529.1 - 0.018 15.0 0.0 0.032 14.2 0.0 1.4 1 0 0 1 1 1 0 tRNA nucleotidyltransferase domain 2 putative CLZ PF16526.5 KXH28535.1 - 0.034 14.5 0.1 0.051 13.9 0.1 1.3 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels HMG_box PF00505.19 KXH28537.1 - 9.2e-17 61.2 0.8 1.4e-16 60.7 0.1 1.7 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KXH28537.1 - 3.3e-11 43.6 1.5 3.3e-11 43.6 0.1 1.8 2 0 0 2 2 2 1 HMG-box domain SAM_1 PF00536.30 KXH28537.1 - 3.8e-11 43.3 0.0 6.4e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KXH28537.1 - 1.4e-08 34.7 0.0 2.8e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) WYL_3 PF18488.1 KXH28537.1 - 0.32 11.4 2.6 0.81 10.1 2.6 1.7 1 0 0 1 1 1 0 WYL domain Fungal_trans PF04082.18 KXH28549.1 - 6.7e-23 81.1 0.0 1.2e-22 80.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH28549.1 - 3.8e-08 33.3 13.0 3.8e-08 33.3 13.0 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_assoc PF16606.5 KXH28549.1 - 0.066 13.4 0.9 0.18 12.1 0.9 1.7 1 0 0 1 1 1 0 Unstructured conserved, between two C2H2-type zinc-fingers Beta_helix PF13229.6 KXH28550.1 - 2.5e-12 46.9 13.2 1.5e-10 41.2 13.2 2.2 1 1 0 1 1 1 1 Right handed beta helix region NosD PF05048.13 KXH28550.1 - 1.6e-05 24.3 8.6 0.0074 15.6 1.7 2.5 1 1 0 2 2 2 2 Periplasmic copper-binding protein (NosD) Chondroitinas_B PF14592.6 KXH28550.1 - 1.7e-05 23.9 0.1 4e-05 22.7 0.0 1.5 2 0 0 2 2 2 1 Chondroitinase B DUF3395 PF11875.8 KXH28552.1 - 3.1e-27 95.4 0.0 5.3e-27 94.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3395) DnaJ PF00226.31 KXH28552.1 - 4.2e-08 33.2 0.1 8.1e-08 32.3 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain Fungal_trans PF04082.18 KXH28553.1 - 1.1e-07 31.1 0.0 1.6e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH28553.1 - 2.1e-06 27.8 10.3 3.9e-06 26.9 10.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_M16_M PF16187.5 KXH28554.1 - 4.2e-96 321.5 1.5 7.8e-96 320.6 1.5 1.5 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16_C PF05193.21 KXH28554.1 - 4.2e-35 121.4 0.1 8.7e-19 68.2 0.0 3.0 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KXH28554.1 - 8e-32 110.3 0.7 1.8e-31 109.1 0.2 2.0 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) CheR_N PF03705.15 KXH28554.1 - 0.048 13.4 0.1 0.31 10.8 0.1 2.4 2 1 1 3 3 3 0 CheR methyltransferase, all-alpha domain MPP6 PF10175.9 KXH28555.1 - 6.4e-09 36.4 13.6 0.0002 21.9 3.9 3.1 2 1 1 3 3 3 2 M-phase phosphoprotein 6 zf-CCHC PF00098.23 KXH28555.1 - 2.4e-06 27.3 4.6 3.8e-06 26.7 4.6 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 KXH28555.1 - 0.00028 20.6 1.8 0.00047 19.9 1.8 1.4 1 0 0 1 1 1 1 Zinc knuckle CDC45 PF02724.14 KXH28555.1 - 0.25 9.6 9.1 0.38 9.0 9.1 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF4746 PF15928.5 KXH28555.1 - 0.76 9.1 6.3 1.1 8.6 6.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Menin PF05053.13 KXH28555.1 - 1.5 7.1 9.6 1.8 6.8 9.6 1.2 1 0 0 1 1 1 0 Menin TFIIA PF03153.13 KXH28555.1 - 1.8 8.5 17.1 0.64 9.9 14.4 1.5 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit NPR3 PF03666.13 KXH28555.1 - 3.4 6.3 8.6 4.8 5.9 8.6 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF2151 PF10221.9 KXH28555.1 - 3.9 6.0 7.6 5.3 5.5 7.6 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator SpoIIIAH PF12685.7 KXH28555.1 - 4.6 7.0 16.5 0.57 10.0 12.5 1.5 2 0 0 2 2 2 0 SpoIIIAH-like protein FAM176 PF14851.6 KXH28555.1 - 6.4 6.4 8.2 0.65 9.6 3.5 1.9 2 0 0 2 2 2 0 FAM176 family TLP-20 PF06088.11 KXH28555.1 - 7.4 6.4 8.2 5.1 7.0 5.6 2.0 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) DAO PF01266.24 KXH28556.1 - 5.2e-41 141.4 0.2 6.5e-41 141.1 0.2 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXH28556.1 - 3.8e-06 27.0 0.8 1.2e-05 25.4 0.7 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain MCRA PF06100.11 KXH28556.1 - 0.0077 15.1 0.2 0.011 14.5 0.2 1.2 1 0 0 1 1 1 1 MCRA family MFS_1 PF07690.16 KXH28557.1 - 6.5e-30 104.2 29.0 2.9e-25 89.0 7.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PDEase_I PF00233.19 KXH28559.1 - 3.8e-65 220.0 0.0 5.4e-65 219.4 0.0 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Peptidase_S10 PF00450.22 KXH28560.1 - 4.2e-104 349.3 2.3 6.1e-104 348.7 2.3 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase SBDS_C PF09377.10 KXH28560.1 - 8.5e-44 148.3 0.0 1.5e-43 147.5 0.0 1.4 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.18 KXH28560.1 - 1.2e-34 118.2 0.1 2.3e-34 117.3 0.1 1.5 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein Carbpep_Y_N PF05388.11 KXH28560.1 - 9.3e-17 61.7 4.7 7.2e-16 58.9 4.7 2.4 1 1 0 1 1 1 1 Carboxypeptidase Y pro-peptide Ribosomal_S13 PF00416.22 KXH28561.1 - 1.5e-49 167.6 3.4 1.3e-48 164.6 3.4 1.9 1 1 0 1 1 1 1 Ribosomal protein S13/S18 Syntaxin-6_N PF09177.11 KXH28561.1 - 0.004 17.7 0.0 0.0074 16.8 0.0 1.4 1 0 0 1 1 1 1 Syntaxin 6, N-terminal PP28 PF10252.9 KXH28561.1 - 0.16 12.5 1.3 0.2 12.1 0.3 1.7 2 0 0 2 2 2 0 Casein kinase substrate phosphoprotein PP28 PA26 PF04636.13 KXH28562.1 - 0.37 9.7 3.3 0.47 9.3 3.3 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DUF4834 PF16118.5 KXH28562.1 - 1.5 9.8 6.6 4.3 8.4 6.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) FAM76 PF16046.5 KXH28562.1 - 1.9 7.8 8.0 2.6 7.3 8.0 1.2 1 0 0 1 1 1 0 FAM76 protein Presenilin PF01080.17 KXH28562.1 - 2.3 6.9 4.7 2.9 6.6 4.7 1.2 1 0 0 1 1 1 0 Presenilin Cas1_AcylT PF07779.12 KXH28563.1 - 2.1e-115 386.4 12.9 3e-115 385.9 12.9 1.2 1 0 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p Sigma_reg_N PF13800.6 KXH28563.1 - 0.74 10.1 4.9 7.7 6.9 0.7 3.1 3 0 0 3 3 3 0 Sigma factor regulator N-terminal Stn1_C PF12659.7 KXH28564.1 - 0.0022 17.9 1.0 2.1 8.3 0.2 2.5 2 0 0 2 2 2 2 Telomere capping C-terminal wHTH Mad3_BUB1_I PF08311.12 KXH28564.1 - 0.049 13.6 0.7 14 5.7 0.0 3.1 3 0 0 3 3 3 0 Mad3/BUB1 homology region 1 TilS PF09179.11 KXH28564.1 - 0.29 11.7 1.3 0.63 10.6 0.0 2.2 3 0 0 3 3 3 0 TilS substrate binding domain Tis11B_N PF04553.12 KXH28565.1 - 0.024 15.2 1.4 0.065 13.8 0.3 1.9 2 0 0 2 2 2 0 Tis11B like protein, N terminus Mucin PF01456.17 KXH28566.1 - 0.77 9.7 5.2 7.7 6.5 1.3 2.5 2 0 0 2 2 2 0 Mucin-like glycoprotein DUF2834 PF11196.8 KXH28566.1 - 0.99 9.8 9.5 0.16 12.4 0.3 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF2834) MARVEL PF01284.23 KXH28567.1 - 7.3e-18 65.0 1.8 9.8e-18 64.6 1.8 1.1 1 0 0 1 1 1 1 Membrane-associating domain Tim17 PF02466.19 KXH28568.1 - 6.7e-25 87.6 5.4 9.9e-25 87.1 5.4 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Endonuclease_5 PF04493.14 KXH28568.1 - 0.0091 15.7 0.0 0.012 15.3 0.0 1.1 1 0 0 1 1 1 1 Endonuclease V eIF-5_eIF-2B PF01873.17 KXH28571.1 - 3.4e-39 133.3 0.0 8.1e-39 132.1 0.0 1.6 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.18 KXH28571.1 - 3.5e-23 81.6 1.6 3.5e-23 81.6 1.6 2.2 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon p450 PF00067.22 KXH28572.1 - 1e-46 159.6 0.0 2.7e-46 158.3 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 DUF1749 PF08538.10 KXH28573.1 - 1.8e-86 289.9 0.0 2.1e-86 289.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.7 KXH28573.1 - 2e-07 31.9 0.0 2.6e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXH28573.1 - 3e-07 30.0 0.0 0.00011 21.5 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KXH28573.1 - 1.4e-06 28.2 0.0 0.00013 21.7 0.0 2.3 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KXH28573.1 - 0.00013 21.5 0.0 0.027 13.9 0.0 2.5 3 0 0 3 3 3 2 Prolyl oligopeptidase family DLH PF01738.18 KXH28573.1 - 0.017 14.7 0.0 2.2 7.8 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family Ser_hydrolase PF06821.13 KXH28573.1 - 0.022 14.6 0.0 0.071 13.0 0.0 1.9 2 1 0 2 2 2 0 Serine hydrolase LIP PF03583.14 KXH28573.1 - 0.08 12.3 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 Secretory lipase Rtt106_N PF18215.1 KXH28574.1 - 0.045 13.5 0.2 0.13 12.1 0.2 1.7 1 0 0 1 1 1 0 Histone chaperone Rtt106 N-terminal domain AA_permease PF00324.21 KXH28575.1 - 8.3e-140 466.5 37.3 1e-139 466.3 37.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KXH28575.1 - 5e-41 140.9 41.9 6.6e-41 140.5 41.9 1.0 1 0 0 1 1 1 1 Amino acid permease Pkinase PF00069.25 KXH28576.1 - 2.3e-39 135.4 0.0 3.4e-39 134.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXH28576.1 - 3.3e-26 92.1 0.0 5.4e-26 91.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXH28576.1 - 0.081 12.2 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 KXH28576.1 - 0.11 12.3 0.3 16 5.4 0.0 2.8 2 1 1 3 3 3 0 Phosphotransferase enzyme family WD40 PF00400.32 KXH28577.1 - 1.3e-12 48.0 0.8 0.65 11.0 0.0 7.0 7 0 0 7 7 7 4 WD domain, G-beta repeat Nucleoporin_N PF08801.11 KXH28577.1 - 0.00054 18.8 0.0 0.49 9.1 0.1 3.0 1 1 2 3 3 3 3 Nup133 N terminal like INSIG PF07281.12 KXH28578.1 - 1.7e-88 295.8 0.2 2.2e-88 295.4 0.2 1.1 1 0 0 1 1 1 1 Insulin-induced protein (INSIG) LON_substr_bdg PF02190.16 KXH28581.1 - 2.3e-28 99.5 0.0 3.7e-28 98.8 0.0 1.3 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain zf-C3HC4_4 PF15227.6 KXH28581.1 - 0.00063 19.8 6.9 0.0013 18.8 6.9 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 KXH28581.1 - 0.094 12.7 6.1 0.17 11.8 6.1 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.25 KXH28581.1 - 0.14 12.0 3.4 0.31 11.0 3.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXH28581.1 - 0.21 11.5 3.0 0.49 10.3 3.0 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXH28581.1 - 0.47 10.5 6.9 1 9.5 6.9 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KXH28581.1 - 0.49 10.3 4.7 0.93 9.4 4.7 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.22 KXH28583.1 - 2.2e-60 200.4 0.0 2.4e-21 75.3 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KXH28583.1 - 6.7e-10 38.6 0.0 4.2e-06 26.4 0.0 3.2 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KXH28583.1 - 7.2e-10 38.6 0.0 0.0093 15.8 0.0 3.4 3 1 0 3 3 3 2 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 KXH28583.1 - 1e-06 28.6 0.1 0.12 12.4 0.0 3.5 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif Cas_Cas2CT1978 PF09707.10 KXH28583.1 - 0.00026 21.0 0.0 0.43 10.7 0.0 2.3 2 0 0 2 2 2 2 CRISPR-associated protein (Cas_Cas2CT1978) RRM_8 PF11835.8 KXH28583.1 - 0.00039 20.6 0.0 0.15 12.3 0.0 2.4 2 0 0 2 2 2 2 RRM-like domain RRM_7 PF16367.5 KXH28583.1 - 0.00073 19.6 0.1 0.45 10.7 0.0 3.1 3 1 0 3 3 3 1 RNA recognition motif RRM_3 PF08777.11 KXH28583.1 - 0.052 13.6 0.0 0.91 9.6 0.0 2.2 2 0 0 2 2 2 0 RNA binding motif SET_assoc PF11767.8 KXH28583.1 - 0.2 11.3 0.0 22 4.8 0.0 2.3 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated CoaE PF01121.20 KXH28584.1 - 2.1e-42 144.8 0.0 7.8e-42 143.0 0.0 1.8 1 1 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.6 KXH28584.1 - 0.0098 16.4 0.1 0.31 11.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KXH28584.1 - 0.081 13.1 0.0 0.66 10.1 0.0 2.3 1 1 0 1 1 1 0 AAA domain adh_short PF00106.25 KXH28587.1 - 6.7e-43 146.4 0.1 8.6e-43 146.1 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXH28587.1 - 1.8e-38 132.4 0.4 3.3e-38 131.6 0.4 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH28587.1 - 8.6e-07 29.0 0.3 6.2e-06 26.2 0.2 2.0 1 1 1 2 2 2 1 KR domain Epimerase PF01370.21 KXH28587.1 - 0.00011 21.7 0.0 0.00023 20.7 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KXH28587.1 - 0.00098 19.1 0.8 0.011 15.6 0.8 2.1 1 1 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KXH28587.1 - 0.0052 16.2 0.0 0.0075 15.7 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KXH28587.1 - 0.006 15.7 0.0 0.0084 15.3 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Ldh_1_N PF00056.23 KXH28587.1 - 0.011 15.9 0.1 0.091 12.9 0.1 2.3 2 1 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 KXH28587.1 - 0.024 14.5 0.0 0.27 11.1 0.0 2.1 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.17 KXH28587.1 - 0.044 12.9 0.1 0.079 12.0 0.1 1.4 1 1 0 1 1 1 0 RmlD substrate binding domain NmrA PF05368.13 KXH28587.1 - 0.08 12.5 0.1 0.21 11.1 0.1 1.8 2 0 0 2 2 2 0 NmrA-like family ApbA PF02558.16 KXH28587.1 - 0.1 12.3 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Sugar_tr PF00083.24 KXH28589.1 - 1.4e-86 291.1 17.3 1.6e-86 291.0 17.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH28589.1 - 6.8e-17 61.4 22.0 5.7e-15 55.1 3.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily YbhQ PF11076.8 KXH28589.1 - 0.015 15.3 0.2 0.031 14.3 0.2 1.5 1 0 0 1 1 1 0 Putative inner membrane protein YbhQ DUF4234 PF14018.6 KXH28589.1 - 0.19 11.9 3.1 0.64 10.2 0.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4234) SGL PF08450.12 KXH28590.1 - 5.5e-27 94.9 0.1 1.2e-26 93.8 0.1 1.5 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 KXH28590.1 - 0.00015 21.9 0.0 0.00036 20.7 0.0 1.6 1 0 0 1 1 1 1 Arylesterase NHL PF01436.21 KXH28590.1 - 0.00066 19.6 0.6 0.079 13.0 0.0 3.4 3 0 0 3 3 3 1 NHL repeat Str_synth PF03088.16 KXH28590.1 - 0.016 15.3 0.0 0.062 13.4 0.0 1.9 1 1 0 1 1 1 0 Strictosidine synthase Abhydrolase_3 PF07859.13 KXH28591.1 - 1.4e-46 159.0 0.0 3.1e-46 157.9 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold COesterase PF00135.28 KXH28591.1 - 4e-07 29.3 0.1 8.3e-07 28.2 0.1 1.4 1 1 0 1 1 1 1 Carboxylesterase family Esterase_phd PF10503.9 KXH28591.1 - 0.022 14.2 0.2 6.5 6.2 0.0 2.5 3 0 0 3 3 3 0 Esterase PHB depolymerase PHD20L1_u1 PF16660.5 KXH28592.1 - 0.019 15.7 7.9 0.019 15.7 7.9 1.6 1 1 0 1 1 1 0 PHD finger protein 20-like protein 1 DUF390 PF04094.14 KXH28592.1 - 0.03 12.6 3.4 0.03 12.6 3.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF390) DUF4614 PF15391.6 KXH28592.1 - 0.11 12.5 4.9 0.13 12.3 4.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) DUF3292 PF11696.8 KXH28592.1 - 0.22 9.8 3.0 0.26 9.6 3.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) Presenilin PF01080.17 KXH28592.1 - 5 5.8 4.8 5.2 5.7 4.8 1.0 1 0 0 1 1 1 0 Presenilin HAD_2 PF13419.6 KXH28593.1 - 3.5e-24 85.9 0.0 5.1e-24 85.3 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KXH28593.1 - 1.4e-12 48.4 0.0 5.7e-12 46.4 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KXH28593.1 - 4.5e-06 26.6 0.0 7.8e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like NIF PF03031.18 KXH28593.1 - 0.0013 18.6 0.0 0.079 12.7 0.0 2.4 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase HAD PF12710.7 KXH28593.1 - 0.0021 18.5 0.0 0.0036 17.7 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Prefoldin PF02996.17 KXH28593.1 - 0.066 13.1 0.1 0.11 12.4 0.1 1.3 1 0 0 1 1 1 0 Prefoldin subunit Hypoth_Ymh PF09509.10 KXH28593.1 - 0.079 12.9 0.1 0.2 11.5 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (Hypoth_ymh) DLH PF01738.18 KXH28595.1 - 6.1e-12 45.6 0.0 7.5e-12 45.3 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S8 PF00082.22 KXH28596.1 - 2.4e-28 99.3 5.0 3.5e-28 98.7 5.0 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 KXH28596.1 - 1.4e-11 44.9 0.0 2.6e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 putAbiC PF16872.5 KXH28597.1 - 0.15 12.8 0.1 0.35 11.6 0.1 1.6 1 0 0 1 1 1 0 Putative phage abortive infection protein DUF5354 PF17305.2 KXH28598.1 - 0.16 12.2 0.3 1.3 9.2 0.0 2.3 1 1 0 2 2 2 0 Family of unknown function (DUF5354) Glyco_hydro_28 PF00295.17 KXH28599.1 - 5.8e-27 94.6 0.2 8.2e-27 94.1 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Pectate_lyase_3 PF12708.7 KXH28599.1 - 1.4e-07 31.6 7.7 7.2e-07 29.3 3.1 3.0 2 1 1 3 3 3 1 Pectate lyase superfamily protein Sulfatase PF00884.23 KXH28600.1 - 1e-44 153.2 0.6 1.3e-42 146.3 0.0 2.8 2 2 0 2 2 2 1 Sulfatase DUF4976 PF16347.5 KXH28600.1 - 2.4e-08 34.2 3.9 1.6e-07 31.6 0.8 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4976) Phosphodiest PF01663.22 KXH28600.1 - 1.9e-07 31.0 0.1 1.2e-05 25.1 0.0 2.6 2 1 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.6 KXH28600.1 - 0.0024 18.6 0.0 0.006 17.3 0.0 1.7 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase DUF1501 PF07394.12 KXH28600.1 - 0.0045 16.1 0.0 0.0089 15.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1501) DUF229 PF02995.17 KXH28600.1 - 0.02 13.5 0.0 0.026 13.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) DUF4994 PF16385.5 KXH28600.1 - 0.078 12.9 0.1 0.15 12.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function STI1 PF17830.1 KXH28600.1 - 0.097 12.6 0.3 0.22 11.5 0.0 1.8 2 0 0 2 2 2 0 STI1 domain Metalloenzyme PF01676.18 KXH28600.1 - 0.11 11.8 0.0 3 7.1 0.0 2.1 2 0 0 2 2 2 0 Metalloenzyme superfamily Spectrin_like PF18373.1 KXH28600.1 - 0.17 12.0 0.0 0.34 11.0 0.0 1.4 1 0 0 1 1 1 0 Spectrin like domain MFS_1 PF07690.16 KXH28601.1 - 2.1e-17 63.1 17.7 3e-17 62.6 17.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1289 PF06945.13 KXH28601.1 - 0.24 11.3 0.2 0.5 10.2 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1289) p450 PF00067.22 KXH28602.1 - 3.8e-62 210.6 0.0 5.2e-62 210.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.20 KXH28603.1 - 3.1e-44 151.2 0.0 5.5e-44 150.4 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KXH28603.1 - 8.8e-33 113.5 0.5 6.4e-31 107.5 0.0 2.6 3 0 0 3 3 3 1 Flavodoxin NAD_binding_1 PF00175.21 KXH28603.1 - 7.8e-21 74.8 0.0 1.8e-20 73.6 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 KXH28603.1 - 0.18 11.9 0.0 2.2 8.4 0.0 2.3 1 1 1 2 2 2 0 Ferric reductase NAD binding domain PGF-CTERM PF18204.1 KXH28603.1 - 4.4 7.4 6.3 9.3 6.4 6.3 1.6 1 0 0 1 1 1 0 PGF-CTERM motif Sugar_tr PF00083.24 KXH28604.1 - 8.6e-107 357.8 27.0 9.9e-107 357.6 27.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH28604.1 - 8.4e-32 110.4 26.1 8.4e-32 110.4 26.1 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Glyco_hydro_115 PF15979.5 KXH28605.1 - 3.6e-133 444.2 0.3 4.8e-133 443.8 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 115 GH115_C PF17829.1 KXH28605.1 - 4e-38 130.9 0.0 8.7e-38 129.8 0.0 1.6 1 0 0 1 1 1 1 Gylcosyl hydrolase family 115 C-terminal domain MFS_1 PF07690.16 KXH28606.1 - 6.9e-28 97.6 28.3 6.9e-28 97.6 28.3 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily MWFE PF15879.5 KXH28606.1 - 0.091 12.9 4.1 3.5 7.9 0.1 3.9 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase MWFE subunit Glyco_hydro_38N PF01074.22 KXH28607.1 - 1.8e-85 286.8 0.3 2.7e-85 286.2 0.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Alpha-mann_mid PF09261.11 KXH28607.1 - 1e-07 32.0 0.0 3.5e-07 30.3 0.0 1.9 2 0 0 2 2 2 1 Alpha mannosidase middle domain FHA PF00498.26 KXH28609.1 - 1.5e-05 25.2 0.0 4.7e-05 23.7 0.0 1.9 1 0 0 1 1 1 1 FHA domain Pkinase PF00069.25 KXH28609.1 - 0.0013 18.1 0.2 0.0025 17.2 0.2 1.4 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KXH28609.1 - 0.024 14.0 0.2 0.06 12.7 0.1 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF5505 PF17610.2 KXH28609.1 - 0.15 12.1 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5505) WXG100 PF06013.12 KXH28610.1 - 0.00027 21.1 5.2 0.00045 20.4 5.2 1.4 1 0 0 1 1 1 1 Proteins of 100 residues with WXG Baculo_PEP_C PF04513.12 KXH28610.1 - 0.0029 17.7 1.6 0.004 17.2 1.6 1.2 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus TolA_bind_tri PF16331.5 KXH28610.1 - 0.0044 17.1 9.3 0.0044 17.1 9.3 2.1 1 1 1 2 2 2 1 TolA binding protein trimerisation Filament PF00038.21 KXH28610.1 - 0.007 16.0 6.6 0.0081 15.8 6.6 1.1 1 0 0 1 1 1 1 Intermediate filament protein Gp-FAR-1 PF05823.12 KXH28610.1 - 0.023 15.1 0.8 0.029 14.7 0.8 1.2 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) LPP PF04728.13 KXH28610.1 - 0.028 14.8 7.7 0.45 10.9 7.7 2.4 1 1 0 1 1 1 0 Lipoprotein leucine-zipper DUF4618 PF15397.6 KXH28610.1 - 0.031 13.7 5.9 0.018 14.5 3.7 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) GrpE PF01025.19 KXH28610.1 - 0.034 13.8 4.2 0.044 13.4 4.2 1.2 1 0 0 1 1 1 0 GrpE NPV_P10 PF05531.12 KXH28610.1 - 0.035 14.6 5.1 0.14 12.7 5.1 1.9 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Tropomyosin_1 PF12718.7 KXH28610.1 - 0.053 13.7 6.2 0.12 12.6 5.9 1.6 1 1 0 1 1 1 0 Tropomyosin like DUF3573 PF12097.8 KXH28610.1 - 0.058 12.2 4.1 0.076 11.8 3.8 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3573) DUF1515 PF07439.11 KXH28610.1 - 0.073 13.1 0.8 0.12 12.5 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) Allexi_40kDa PF05549.11 KXH28610.1 - 0.081 12.4 1.8 0.093 12.2 1.8 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein DUF5344 PF17279.2 KXH28610.1 - 0.082 13.5 3.6 0.93 10.1 3.6 2.1 1 1 0 1 1 1 0 Family of unknown function (DUF5344) NINJA_B PF16136.5 KXH28610.1 - 0.091 13.1 3.2 0.15 12.4 3.2 1.4 1 0 0 1 1 1 0 Putative nuclear localisation signal V-ATPase_G_2 PF16999.5 KXH28610.1 - 0.15 12.5 9.2 0.26 11.7 9.2 1.5 1 1 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit Lant_dehydr_C PF14028.6 KXH28610.1 - 0.22 11.0 5.0 0.19 11.2 3.8 1.5 1 1 1 2 2 2 0 Lantibiotic biosynthesis dehydratase C-term DUF4407 PF14362.6 KXH28610.1 - 0.23 10.8 9.7 0.43 9.9 9.7 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Sec2p PF06428.11 KXH28610.1 - 0.33 10.9 5.7 0.23 11.4 3.3 1.8 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p Spc24 PF08286.11 KXH28610.1 - 0.43 10.8 6.9 25 5.2 6.4 2.3 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 TetR_C_24 PF17932.1 KXH28610.1 - 0.66 10.3 3.7 5.1 7.4 1.0 2.1 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain TMPIT PF07851.13 KXH28610.1 - 0.68 9.1 3.7 0.8 8.9 3.7 1.2 1 0 0 1 1 1 0 TMPIT-like protein GIT_CC PF16559.5 KXH28610.1 - 0.89 9.5 8.5 0.1 12.5 3.7 1.8 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor Uso1_p115_C PF04871.13 KXH28610.1 - 1.7 9.0 8.8 0.79 10.1 5.8 1.8 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region LCIB_C_CA PF18599.1 KXH28610.1 - 6.3 6.0 5.5 9.9 5.4 2.8 1.9 1 1 1 2 2 2 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases SseC PF04888.12 KXH28610.1 - 6.5 6.3 8.5 8.4 5.9 8.5 1.1 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family DUF3914 PF13053.6 KXH28611.1 - 0.074 13.4 0.0 0.12 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3914) Sugarporin_N PF11471.8 KXH28613.1 - 0.75 9.8 4.7 0.17 11.9 1.3 1.6 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension F-box-like PF12937.7 KXH28614.1 - 0.028 14.3 0.0 0.067 13.1 0.0 1.7 1 0 0 1 1 1 0 F-box-like SRF-TF PF00319.18 KXH28615.1 - 0.059 12.9 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 SRF-type transcription factor (DNA-binding and dimerisation domain) Pkinase PF00069.25 KXH28617.1 - 4.9e-13 49.1 0.0 8.7e-13 48.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KXH28617.1 - 6.7e-06 26.2 0.0 1.3e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 KXH28617.1 - 1.7e-05 24.3 0.0 2.7e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase NAD_binding_6 PF08030.12 KXH28617.1 - 0.00079 19.6 0.0 0.0038 17.4 0.0 1.9 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Kdo PF06293.14 KXH28617.1 - 0.00087 18.7 0.0 0.0017 17.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KXH28617.1 - 0.0048 16.5 0.0 0.0084 15.7 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 KXH28617.1 - 0.047 12.5 0.2 0.086 11.6 0.2 1.3 1 0 0 1 1 1 0 Fungal protein kinase DUF3723 PF12520.8 KXH28620.1 - 1.4e-69 235.1 0.0 1.5e-65 221.9 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3723) NTNH_C PF08470.10 KXH28621.1 - 0.19 11.6 0.0 0.29 11.0 0.0 1.2 1 0 0 1 1 1 0 Nontoxic nonhaemagglutinin C-terminal GyrI-like PF06445.15 KXH28622.1 - 0.034 14.4 0.0 0.062 13.6 0.0 1.4 1 0 0 1 1 1 0 GyrI-like small molecule binding domain XFP_N PF09364.10 KXH28623.1 - 0.052 12.4 0.0 0.079 11.8 0.0 1.2 1 0 0 1 1 1 0 XFP N-terminal domain zf-C2H2 PF00096.26 KXH28736.1 - 0.0061 17.0 6.6 0.22 12.0 1.1 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXH28736.1 - 0.015 16.1 21.5 0.031 15.1 1.8 3.9 4 0 0 4 4 4 0 C2H2-type zinc finger zf-met PF12874.7 KXH28736.1 - 0.015 15.6 6.0 0.61 10.5 0.6 3.2 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Aldo_ket_red PF00248.21 KXH28738.1 - 1.6e-61 208.1 0.0 1.8e-61 207.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family HHH_7 PF14635.6 KXH28738.1 - 0.029 14.7 0.1 0.13 12.7 0.0 1.9 1 1 1 2 2 2 0 Helix-hairpin-helix motif Sugar_tr PF00083.24 KXH28739.1 - 1.2e-83 281.4 19.0 1.4e-83 281.3 19.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH28739.1 - 1.4e-12 47.2 35.1 1.4e-12 47.2 35.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Romo1 PF10247.9 KXH28739.1 - 8 6.9 7.6 3.9 7.9 0.3 3.7 3 0 0 3 3 3 0 Reactive mitochondrial oxygen species modulator 1 WD40 PF00400.32 KXH28740.1 - 8.7e-11 42.2 4.0 0.26 12.2 0.0 6.5 5 1 1 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXH28740.1 - 0.2 12.0 0.0 21 5.5 0.0 3.5 3 1 2 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain AAA_12 PF13087.6 KXH28741.1 - 1.2e-34 119.7 0.0 2e-34 119.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KXH28741.1 - 1.8e-22 80.4 0.1 3.2e-13 50.1 0.1 2.2 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KXH28741.1 - 3.9e-09 36.5 0.4 1.3e-06 28.3 0.1 2.3 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 KXH28741.1 - 1.2e-07 32.2 0.0 1.5e-06 28.7 0.0 2.6 2 1 0 2 2 1 1 AAA domain AAA_16 PF13191.6 KXH28741.1 - 6.4e-07 29.9 0.2 0.24 11.8 0.1 3.5 3 0 0 3 3 3 2 AAA ATPase domain PhoH PF02562.16 KXH28741.1 - 0.0016 17.9 0.1 0.0035 16.8 0.1 1.5 1 0 0 1 1 1 1 PhoH-like protein AAA_22 PF13401.6 KXH28741.1 - 0.014 15.7 0.1 2.1 8.6 0.0 3.4 4 0 0 4 4 4 0 AAA domain ATPase PF06745.13 KXH28741.1 - 0.022 14.1 0.2 0.055 12.8 0.0 1.6 2 0 0 2 2 2 0 KaiC Helicase_RecD PF05127.14 KXH28741.1 - 0.025 14.4 0.2 0.37 10.6 0.0 2.3 2 0 0 2 2 2 0 Helicase T2SSE PF00437.20 KXH28741.1 - 0.034 13.2 0.2 0.076 12.1 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_5 PF07728.14 KXH28741.1 - 0.039 14.0 0.0 0.35 10.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KXH28741.1 - 0.041 14.0 0.9 0.095 12.9 0.2 2.0 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 KXH28741.1 - 0.042 13.6 0.1 0.12 12.1 0.0 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein ResIII PF04851.15 KXH28741.1 - 0.064 13.3 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA PF00004.29 KXH28741.1 - 0.44 11.0 1.8 7.7 6.9 1.3 2.9 2 1 1 3 3 3 0 ATPase family associated with various cellular activities (AAA) SWIRM PF04433.17 KXH28742.1 - 1.2e-13 51.2 0.0 2.7e-13 50.0 0.0 1.6 1 0 0 1 1 1 1 SWIRM domain UPF0220 PF05255.11 KXH28750.1 - 2.1e-67 225.8 4.8 2.4e-67 225.6 4.8 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) DUF3169 PF11368.8 KXH28750.1 - 0.58 9.6 3.7 0.2 11.1 1.2 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) SMI1_KNR4 PF09346.10 KXH28751.1 - 1.6e-31 109.4 0.0 3.7e-31 108.3 0.0 1.6 1 1 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) DNA_pol_A_exo1 PF01612.20 KXH28752.1 - 1.3e-15 57.5 0.0 2e-15 57.0 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease LSM PF01423.22 KXH28753.1 - 3.2e-22 78.0 0.1 3.5e-22 77.9 0.1 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KXH28753.1 - 0.025 14.7 0.0 0.029 14.5 0.0 1.1 1 0 0 1 1 1 0 Ataxin 2 SM domain Aa_trans PF01490.18 KXH28754.1 - 3.8e-83 279.5 30.7 4.7e-83 279.2 30.7 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein RNA_pol_L_2 PF13656.6 KXH28754.1 - 8.6e-23 79.9 0.3 1.5e-22 79.1 0.3 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 KXH28754.1 - 5e-05 22.7 0.1 0.00021 20.6 0.1 2.1 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain AA_permease PF00324.21 KXH28755.1 - 1.1e-63 215.5 31.4 1.4e-63 215.2 31.4 1.1 1 0 0 1 1 1 1 Amino acid permease SLC12 PF03522.15 KXH28755.1 - 5.9e-24 84.9 2.3 4.4e-09 35.9 0.0 3.3 3 0 0 3 3 3 3 Solute carrier family 12 AA_permease_2 PF13520.6 KXH28755.1 - 2.4e-17 62.9 37.0 5.1e-17 61.8 37.0 1.5 1 1 0 1 1 1 1 Amino acid permease FXR_C1 PF16096.5 KXH28755.1 - 0.13 12.5 0.4 0.34 11.1 0.4 1.6 1 0 0 1 1 1 0 Fragile X-related 1 protein C-terminal region 2 Blt1_C PF17183.4 KXH28755.1 - 0.2 11.3 0.3 0.48 10.0 0.3 1.6 1 0 0 1 1 1 0 Get5 carboxyl domain MTS PF05175.14 KXH28758.1 - 9.5e-11 41.5 0.0 9.4e-10 38.3 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_31 PF13847.6 KXH28758.1 - 6.8e-08 32.4 0.0 2.1e-07 30.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KXH28758.1 - 3.1e-06 26.8 0.0 4.5e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 KXH28758.1 - 1.1e-05 25.3 0.0 4.6e-05 23.3 0.0 1.9 1 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH28758.1 - 1.4e-05 25.7 0.0 4e-05 24.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain N6_Mtase PF02384.16 KXH28758.1 - 0.00012 21.5 0.0 0.00016 21.1 0.0 1.1 1 0 0 1 1 1 1 N-6 DNA Methylase PrmC_N PF17827.1 KXH28758.1 - 0.00016 22.2 0.1 0.00043 20.8 0.1 1.7 1 0 0 1 1 1 1 PrmC N-terminal domain Methyltransf_10 PF05971.12 KXH28758.1 - 0.0022 17.4 0.0 0.0031 16.9 0.0 1.1 1 0 0 1 1 1 1 RNA methyltransferase FtsJ PF01728.19 KXH28758.1 - 0.0099 16.0 0.0 0.014 15.5 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Met_10 PF02475.16 KXH28758.1 - 0.012 15.4 0.0 0.019 14.7 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_32 PF13679.6 KXH28758.1 - 0.013 15.5 0.0 0.021 14.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain AviRa PF11599.8 KXH28758.1 - 0.082 12.4 0.1 2.5 7.5 0.0 2.1 1 1 1 2 2 2 0 RRNA methyltransferase AviRa Methyltransf_11 PF08241.12 KXH28758.1 - 0.082 13.6 0.0 0.2 12.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.15 KXH28758.1 - 0.13 11.9 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 UPF0020 PF01170.18 KXH28758.1 - 0.13 12.0 0.0 0.51 10.0 0.0 1.8 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 Ubie_methyltran PF01209.18 KXH28758.1 - 0.18 11.1 0.0 0.44 9.9 0.0 1.5 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Aminotran_1_2 PF00155.21 KXH28759.1 - 4.5e-45 154.4 0.0 5.6e-45 154.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II WD40 PF00400.32 KXH28760.1 - 6.9e-19 67.8 6.6 5.5e-06 27.0 0.7 6.2 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXH28760.1 - 1.4e-09 38.1 0.2 0.00085 19.6 0.0 4.9 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 KXH28760.1 - 0.00093 18.8 3.7 0.25 10.9 0.0 2.3 1 1 1 2 2 2 2 PQQ-like domain PQQ_3 PF13570.6 KXH28760.1 - 0.011 16.2 4.2 15 6.3 0.2 4.5 5 0 0 5 5 5 0 PQQ-like domain DUF5046 PF16465.5 KXH28760.1 - 0.04 13.4 0.1 0.081 12.4 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5046) PQQ PF01011.21 KXH28760.1 - 0.056 13.4 0.3 60 3.8 0.1 3.9 3 0 0 3 3 3 0 PQQ enzyme repeat Glyco_transf_15 PF01793.16 KXH28761.1 - 6.9e-116 387.0 8.6 8.4e-116 386.7 8.6 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase GCP_N_terminal PF17681.1 KXH28762.1 - 6.2e-34 118.0 0.0 8.9e-34 117.5 0.0 1.2 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 KXH28762.1 - 9e-27 94.3 0.0 2.3e-26 93.0 0.0 1.7 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP5-Mod21 PF14609.6 KXH28762.1 - 6.1e-11 41.4 0.1 8.8e-11 40.9 0.1 1.2 1 0 0 1 1 1 1 gamma-Tubulin ring complex non-core subunit mod21 Atypical_Card PF18461.1 KXH28762.1 - 0.027 14.7 0.0 0.07 13.4 0.0 1.6 1 0 0 1 1 1 0 Atypical caspase recruitment domain DUF572 PF04502.13 KXH28763.1 - 9.4e-68 229.3 5.9 1.1e-67 229.0 5.9 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) DUF951 PF06107.11 KXH28763.1 - 0.16 11.9 0.5 13 5.7 0.0 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF951) zf-ACC PF17848.1 KXH28763.1 - 1.8 8.7 4.0 9.9 6.3 1.0 2.3 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain CDC45 PF02724.14 KXH28763.1 - 3.5 5.8 7.7 4.5 5.5 7.7 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4407 PF14362.6 KXH28763.1 - 5.9 6.2 8.2 8.1 5.7 8.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PBP PF01161.20 KXH28764.1 - 6.6e-17 62.1 0.1 1.1e-16 61.3 0.1 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Pyr_redox_2 PF07992.14 KXH28765.1 - 5.8e-31 107.8 0.2 6.9e-31 107.6 0.2 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXH28765.1 - 6.3e-11 42.7 0.1 2.5e-09 37.6 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXH28765.1 - 3.5e-06 27.1 1.3 0.073 13.1 0.0 3.5 4 0 0 4 4 4 3 FAD-NAD(P)-binding K_oxygenase PF13434.6 KXH28765.1 - 0.00045 19.5 0.2 0.11 11.6 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.22 KXH28765.1 - 0.0066 15.6 3.0 0.24 10.4 0.4 2.7 2 1 1 3 3 3 2 Glucose inhibited division protein A Lycopene_cycl PF05834.12 KXH28765.1 - 0.021 13.9 1.5 0.15 11.0 0.0 2.5 3 0 0 3 3 3 0 Lycopene cyclase protein Catalase_C PF18011.1 KXH28765.1 - 0.042 13.5 0.1 0.077 12.6 0.1 1.4 1 0 0 1 1 1 0 C-terminal domain found in long catalases HI0933_like PF03486.14 KXH28765.1 - 0.046 12.4 2.1 3.3 6.3 0.1 3.2 3 1 1 4 4 4 0 HI0933-like protein DAO PF01266.24 KXH28765.1 - 0.082 12.5 7.7 4.4 6.8 0.0 3.7 3 1 0 4 4 4 0 FAD dependent oxidoreductase Big_1 PF02369.16 KXH28765.1 - 0.19 11.8 5.7 1.9 8.6 1.0 2.5 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 1) cobW PF02492.19 KXH28768.1 - 5.7e-41 140.0 0.0 9.2e-41 139.4 0.0 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.14 KXH28768.1 - 0.00071 19.5 1.0 0.0011 18.9 0.0 1.8 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B RsgA_GTPase PF03193.16 KXH28768.1 - 0.0071 16.3 0.0 4.7 7.1 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase Viral_helicase1 PF01443.18 KXH28768.1 - 0.0087 15.8 0.0 0.02 14.6 0.0 1.7 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_29 PF13555.6 KXH28768.1 - 0.012 15.3 0.5 0.34 10.7 0.1 2.9 3 0 0 3 3 3 0 P-loop containing region of AAA domain AAA_22 PF13401.6 KXH28768.1 - 0.015 15.6 0.0 0.035 14.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 KXH28768.1 - 0.068 13.1 0.1 0.15 12.0 0.1 1.5 1 0 0 1 1 1 0 NTPase DUF2075 PF09848.9 KXH28768.1 - 0.07 12.4 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.6 KXH28768.1 - 0.13 12.6 0.1 0.43 10.9 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain DUF463 PF04317.12 KXH28768.1 - 0.16 10.8 0.1 0.26 10.2 0.1 1.3 1 0 0 1 1 1 0 YcjX-like family, DUF463 tRNA-synt_1 PF00133.22 KXH28769.1 - 3.6e-51 174.1 0.0 3e-18 65.4 0.2 6.0 2 1 3 5 5 5 5 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.6 KXH28769.1 - 9.5e-41 139.3 0.0 1.8e-40 138.4 0.0 1.5 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.11 KXH28769.1 - 6.8e-29 100.8 0.7 1.3e-19 70.2 0.0 4.5 4 1 1 5 5 5 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 KXH28769.1 - 2.3e-12 47.1 0.0 4.5e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 KXH28769.1 - 0.014 14.8 0.0 4.7 6.5 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain tRNA-synt_1c PF00749.21 KXH28769.1 - 0.077 11.9 0.3 6.3 5.6 0.1 2.3 2 0 0 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain MTHFR PF02219.17 KXH28770.1 - 6.6e-101 337.4 0.0 9.4e-101 336.9 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase BTRD1 PF17660.1 KXH28771.1 - 0.023 14.5 0.0 0.048 13.5 0.0 1.5 1 0 0 1 1 1 0 Bacterial tandem repeat domain 1 HTH_WhiA PF02650.14 KXH28771.1 - 0.094 13.1 0.0 0.2 12.0 0.0 1.6 1 0 0 1 1 1 0 WhiA C-terminal HTH domain PQ-loop PF04193.14 KXH28772.1 - 1.2e-17 63.4 4.5 2.7e-12 46.3 1.3 2.7 2 0 0 2 2 2 2 PQ loop repeat GATase_5 PF13507.6 KXH28773.1 - 5.5e-96 320.7 0.0 8.1e-96 320.1 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 KXH28773.1 - 9.1e-37 126.6 0.3 4.2e-24 85.5 0.1 2.5 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain FGAR-AT_N PF18076.1 KXH28773.1 - 4.5e-24 84.6 0.0 8.5e-24 83.8 0.0 1.5 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase N-terminal FGAR-AT_linker PF18072.1 KXH28773.1 - 5.4e-23 81.3 0.0 1.3e-22 80.0 0.0 1.7 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain Zn_clus PF00172.18 KXH28775.1 - 4.8e-07 29.8 8.6 7.9e-07 29.1 8.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cpn60_TCP1 PF00118.24 KXH28776.1 - 0.00051 18.8 0.0 0.00059 18.6 0.0 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family ProRS-C_1 PF09180.11 KXH28777.1 - 6.1e-22 77.6 0.2 1.3e-21 76.6 0.2 1.6 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.25 KXH28777.1 - 1.3e-20 74.2 0.0 2.6e-20 73.2 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KXH28777.1 - 1.2e-17 63.8 0.0 3.3e-17 62.4 0.0 1.8 1 0 0 1 1 1 1 Anticodon binding domain MT0933_antitox PF14013.6 KXH28777.1 - 3.6 8.0 10.7 1.4 9.2 7.2 2.1 2 0 0 2 2 2 0 MT0933-like antitoxin protein zf-C2H2_2 PF12756.7 KXH28778.1 - 3.4e-26 91.5 8.0 3.7e-25 88.2 3.8 2.3 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 KXH28778.1 - 0.21 11.9 6.5 1.5 9.2 0.2 2.9 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding HNF-1_N PF04814.13 KXH28778.1 - 0.95 10.0 7.4 0.27 11.8 2.7 2.2 2 0 0 2 2 2 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus FPN1 PF06963.12 KXH28780.1 - 0.21 10.1 0.0 0.27 9.8 0.0 1.1 1 0 0 1 1 1 0 Ferroportin1 (FPN1) Lipase_GDSL_2 PF13472.6 KXH28781.1 - 1.4e-13 51.6 0.1 3.1e-12 47.3 0.1 2.3 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KXH28781.1 - 3.7e-07 30.3 0.0 1.1e-06 28.7 0.0 1.9 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase LRR_4 PF12799.7 KXH28782.1 - 0.012 16.0 0.3 0.99 9.9 0.0 3.8 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) Glyco_transf_28 PF03033.20 KXH28783.1 - 3.4e-22 79.0 0.0 7.5e-22 77.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain Glyco_tran_28_C PF04101.16 KXH28783.1 - 0.0046 17.0 0.0 0.008 16.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain UDPGT PF00201.18 KXH28783.1 - 0.0063 15.3 0.0 0.0092 14.8 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase ATG_C PF09333.11 KXH28783.1 - 0.039 14.3 0.1 0.32 11.4 0.0 2.5 3 0 0 3 3 3 0 Autophagy-related protein C terminal domain HRXXH PF13933.6 KXH28784.1 - 4.4e-108 360.5 0.0 6e-108 360.0 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family Aspzincin_M35 PF14521.6 KXH28784.1 - 6.7e-06 26.7 0.2 1.8e-05 25.3 0.2 1.7 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase Sporozoite_P67 PF05642.11 KXH28784.1 - 0.16 10.0 0.0 0.2 9.7 0.0 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen BIR PF00653.21 KXH28785.1 - 5.4e-44 148.7 8.6 1.3e-21 77.0 0.8 3.3 3 0 0 3 3 3 2 Inhibitor of Apoptosis domain AT_hook PF02178.19 KXH28785.1 - 0.54 10.3 12.8 0.19 11.7 1.5 3.9 2 1 0 2 2 2 0 AT hook motif VitD-bind_III PF09164.10 KXH28786.1 - 0.15 12.1 2.9 0.38 10.8 2.9 1.7 1 0 0 1 1 1 0 Vitamin D binding protein, domain III Cutinase PF01083.22 KXH28787.1 - 1.9e-33 115.9 0.2 2.3e-33 115.6 0.2 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 KXH28787.1 - 0.05 13.1 0.0 0.083 12.4 0.0 1.4 1 0 0 1 1 1 0 PE-PPE domain Abhydrolase_1 PF00561.20 KXH28787.1 - 0.074 12.7 0.0 0.63 9.6 0.0 2.0 2 0 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 KXH28787.1 - 0.091 12.6 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase VirJ PF06057.11 KXH28787.1 - 0.15 11.9 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) BTB PF00651.31 KXH28788.1 - 0.00021 21.5 0.0 0.0049 17.1 0.0 2.2 2 0 0 2 2 2 1 BTB/POZ domain Gpr1_Fun34_YaaH PF01184.19 KXH28789.1 - 2e-28 99.4 23.6 2.6e-28 99.1 23.6 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family CoA_binding_2 PF13380.6 KXH28790.1 - 1.4e-27 96.5 0.0 1.6e-27 96.3 0.0 1.1 1 0 0 1 1 1 1 CoA binding domain Methyltransf_11 PF08241.12 KXH28791.1 - 7.8e-20 71.3 0.0 1.3e-19 70.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH28791.1 - 7.4e-18 65.1 0.1 1.6e-17 64.0 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH28791.1 - 1.3e-09 38.7 0.0 2.1e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH28791.1 - 1.3e-09 38.0 0.0 2.1e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXH28791.1 - 5.5e-07 29.6 0.0 9.4e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXH28791.1 - 1.1e-05 24.9 0.0 1.6e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KXH28791.1 - 3.7e-05 23.3 0.1 9.7e-05 22.0 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain DREV PF05219.12 KXH28791.1 - 0.0036 16.5 0.0 0.0048 16.0 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_18 PF12847.7 KXH28791.1 - 0.02 14.8 0.0 0.06 13.3 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain PrmA PF06325.13 KXH28791.1 - 0.037 13.4 0.0 0.066 12.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) NodS PF05401.11 KXH28791.1 - 0.048 13.3 0.0 0.069 12.8 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) tRNA_U5-meth_tr PF05958.11 KXH28791.1 - 0.075 12.0 0.0 0.11 11.5 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Methyltransf_32 PF13679.6 KXH28791.1 - 0.2 11.6 0.0 0.34 10.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_8 PF05148.15 KXH28791.1 - 0.23 11.3 0.0 1.1 9.1 0.0 1.8 1 1 0 1 1 1 0 Hypothetical methyltransferase EF-hand_7 PF13499.6 KXH28792.1 - 2.7e-13 50.1 0.3 2.8e-08 34.1 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 KXH28792.1 - 5.7e-12 45.8 0.0 1.5e-05 25.2 0.0 2.5 2 1 0 2 2 2 2 EF-hand domain EF-hand_6 PF13405.6 KXH28792.1 - 2.7e-10 39.3 0.5 0.0034 17.2 0.0 3.7 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 KXH28792.1 - 6.6e-10 37.8 0.2 0.019 14.5 0.0 3.9 4 1 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 KXH28792.1 - 8.9e-09 35.1 0.1 2.2e-05 24.2 0.1 3.2 3 0 0 3 3 3 2 EF-hand domain pair FGAR-AT_linker PF18072.1 KXH28792.1 - 0.1 13.2 0.1 5.2 7.7 0.1 2.3 2 0 0 2 2 2 0 Formylglycinamide ribonucleotide amidotransferase linker domain Peptidase_M3 PF01432.20 KXH28793.1 - 1.3e-157 525.8 0.0 1.7e-157 525.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M2 PF01401.18 KXH28793.1 - 0.1 11.2 0.0 0.99 7.9 0.0 2.0 2 0 0 2 2 2 0 Angiotensin-converting enzyme BTB PF00651.31 KXH28794.1 - 5.3e-08 33.1 0.0 1.6e-06 28.3 0.0 2.6 3 1 0 3 3 3 1 BTB/POZ domain THAP PF05485.12 KXH28794.1 - 0.075 14.0 0.0 0.16 12.9 0.0 1.5 1 0 0 1 1 1 0 THAP domain Mso1_Sec1_bdg PF14475.6 KXH28794.1 - 1.2 8.8 4.8 2.6 7.7 0.0 2.4 2 0 0 2 2 2 0 Sec1-binding region of Mso1 BTB PF00651.31 KXH28795.1 - 0.15 12.3 0.0 1.9 8.8 0.0 2.2 2 0 0 2 2 2 0 BTB/POZ domain dCMP_cyt_deam_1 PF00383.23 KXH28796.1 - 5.5e-07 29.4 0.5 5.5e-07 29.4 0.5 1.6 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KXH28796.1 - 0.013 15.2 0.5 0.047 13.4 0.5 1.8 1 1 0 1 1 1 0 MafB19-like deaminase BTB PF00651.31 KXH28797.1 - 0.0012 19.1 0.0 0.002 18.4 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Abhydrolase_3 PF07859.13 KXH28798.1 - 1.6e-29 103.3 0.0 3.3e-29 102.3 0.0 1.4 2 0 0 2 2 2 1 alpha/beta hydrolase fold COesterase PF00135.28 KXH28798.1 - 6.2e-06 25.3 0.0 4e-05 22.7 0.0 1.8 2 0 0 2 2 2 1 Carboxylesterase family AXE1 PF05448.12 KXH28798.1 - 9.7e-05 21.2 0.0 0.00023 20.0 0.0 1.5 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) Abhydrolase_6 PF12697.7 KXH28798.1 - 0.0022 18.6 0.4 0.0033 18.1 0.4 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KXH28798.1 - 0.0077 15.7 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family SMK-1 PF04802.15 KXH28934.1 - 3.6e-84 281.4 0.1 6.8e-84 280.5 0.1 1.5 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 DUF5630 PF18632.1 KXH28934.1 - 0.16 11.3 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5630) Mg_trans_NIPA PF05653.14 KXH28957.1 - 5.8e-17 61.7 11.9 1e-16 60.9 11.9 1.3 1 1 0 1 1 1 1 Magnesium transporter NIPA PUNUT PF16913.5 KXH28957.1 - 0.00061 19.1 2.0 0.00061 19.1 2.0 2.2 1 1 1 2 2 2 1 Purine nucleobase transmembrane transport EamA PF00892.20 KXH28957.1 - 0.006 16.8 3.4 0.006 16.8 3.4 2.7 2 1 1 3 3 3 2 EamA-like transporter family Neurensin PF14927.6 KXH28957.1 - 0.013 15.2 0.4 1.1 9.0 0.1 2.6 2 0 0 2 2 2 0 Neurensin COX4_pro_2 PF07835.12 KXH28957.1 - 0.23 11.6 0.2 0.23 11.6 0.2 2.5 3 0 0 3 3 3 0 Bacterial aa3 type cytochrome c oxidase subunit IV DUF3094 PF11293.8 KXH28957.1 - 7.5 6.4 6.9 1.4 8.7 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3094) vATP-synt_E PF01991.18 KXH28958.1 - 1.5e-69 233.4 11.6 1.8e-69 233.2 11.6 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit Methyltransf_7 PF03492.15 KXH28958.1 - 1.9 7.6 5.5 0.62 9.2 3.1 1.4 2 0 0 2 2 2 0 SAM dependent carboxyl methyltransferase NfrA_C PF13283.6 KXH28959.1 - 0.15 11.5 0.1 0.27 10.7 0.1 1.3 1 0 0 1 1 1 0 Bacteriophage N adsorption protein A C-term MFS_1 PF07690.16 KXH28966.1 - 2.2e-15 56.5 32.4 2.6e-15 56.2 32.4 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans_2 PF11951.8 KXH28969.1 - 9.2e-06 24.7 0.2 2.1e-05 23.5 0.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KXH29386.1 - 0.0046 17.3 3.7 0.4 11.2 0.4 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXH29386.1 - 0.027 15.3 2.0 10 7.2 0.2 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KXH29386.1 - 0.13 12.8 1.9 0.13 12.7 0.0 2.1 2 0 0 2 2 2 0 Zinc-finger double domain Lectin_leg-like PF03388.13 KXH29465.1 - 3.6e-65 219.5 0.0 4.7e-65 219.1 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family Lectin_legB PF00139.19 KXH29465.1 - 2.6e-05 23.9 0.0 0.0013 18.3 0.0 2.1 1 1 0 1 1 1 1 Legume lectin domain zf-Tim10_DDP PF02953.15 KXH29466.1 - 5e-23 80.5 1.6 6.4e-23 80.2 1.6 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF2040 PF09745.9 KXH29467.1 - 5.7e-39 132.9 24.2 5.7e-39 132.9 24.2 3.5 3 1 0 3 3 3 1 Coiled-coil domain-containing protein 55 (DUF2040) DUF2315 PF10231.9 KXH29467.1 - 5.2 7.2 11.7 0.12 12.5 4.0 2.2 2 0 0 2 2 2 0 Apoptogenic protein 1 LMBR1 PF04791.16 KXH29468.1 - 8.7e-108 361.4 6.8 9.9e-108 361.2 6.8 1.0 1 0 0 1 1 1 1 LMBR1-like membrane protein CAF1 PF04857.20 KXH29469.1 - 1.7e-22 80.0 0.1 1.7e-10 40.6 0.0 2.2 2 0 0 2 2 2 2 CAF1 family ribonuclease RFX_DNA_binding PF02257.15 KXH29469.1 - 0.18 12.5 0.0 0.56 10.9 0.0 1.8 2 0 0 2 2 2 0 RFX DNA-binding domain NDUF_B12 PF08122.12 KXH29470.1 - 1.3e-24 86.0 0.7 1.8e-24 85.5 0.7 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family DUF812 PF05667.11 KXH29471.1 - 0.0034 16.4 5.2 0.005 15.8 5.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Spc7 PF08317.11 KXH29471.1 - 0.0045 15.9 11.2 0.0045 15.9 11.2 1.5 2 0 0 2 2 2 1 Spc7 kinetochore protein Golgin_A5 PF09787.9 KXH29471.1 - 0.023 14.2 13.3 0.036 13.5 13.3 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 Cwf_Cwc_15 PF04889.12 KXH29471.1 - 0.029 14.1 9.0 0.045 13.5 9.0 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein MAD PF05557.13 KXH29471.1 - 0.054 11.9 12.8 0.49 8.7 11.6 2.0 2 0 0 2 2 2 0 Mitotic checkpoint protein UPF0565 PF10561.9 KXH29471.1 - 0.079 12.1 0.9 0.12 11.6 0.9 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 Atg14 PF10186.9 KXH29471.1 - 0.08 12.0 6.1 0.07 12.2 5.0 1.5 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 CLZ PF16526.5 KXH29471.1 - 0.25 11.7 7.6 5.4 7.5 6.6 2.6 2 1 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Fib_alpha PF08702.10 KXH29471.1 - 0.28 11.3 6.0 0.4 10.9 4.4 2.0 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Phage_GPO PF05929.11 KXH29471.1 - 0.44 10.1 8.7 0.76 9.4 8.7 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase FlaC_arch PF05377.11 KXH29471.1 - 1.1 9.7 4.1 31 5.1 0.0 2.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Cnn_1N PF07989.11 KXH29471.1 - 1.3 9.3 10.5 15 5.8 6.1 3.2 3 1 0 3 3 3 0 Centrosomin N-terminal motif 1 ZapB PF06005.12 KXH29471.1 - 1.4 9.4 0.0 1.4 9.4 0.0 2.9 2 1 1 3 3 3 0 Cell division protein ZapB Peptidase_S64 PF08192.11 KXH29471.1 - 2.8 6.3 6.3 3.4 6.0 6.3 1.2 1 0 0 1 1 1 0 Peptidase family S64 DUF4407 PF14362.6 KXH29471.1 - 3.5 6.9 10.4 2.5 7.4 8.9 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) eIF-6 PF01912.18 KXH29472.1 - 1.8e-81 272.3 0.3 2.4e-81 271.8 0.3 1.2 1 0 0 1 1 1 1 eIF-6 family NRDE-2 PF08424.10 KXH29473.1 - 2.5e-99 332.5 0.3 1.7e-98 329.7 0.2 2.4 3 0 0 3 3 3 1 NRDE-2, necessary for RNA interference TPR_17 PF13431.6 KXH29473.1 - 0.063 13.7 0.2 1.4 9.5 0.2 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 KXH29473.1 - 1.2 10.2 11.3 13 7.0 0.0 6.7 8 1 0 8 8 8 0 Tetratricopeptide repeat Voltage_CLC PF00654.20 KXH29474.1 - 1e-90 304.5 28.2 1.7e-90 303.8 25.1 2.1 2 0 0 2 2 2 2 Voltage gated chloride channel Aminotran_3 PF00202.21 KXH29475.1 - 8.3e-122 406.7 0.0 9.5e-122 406.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 KXH29475.1 - 0.14 11.3 0.0 0.22 10.7 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II SRI PF08236.11 KXH29477.1 - 2.5e-22 78.8 5.9 8.1e-22 77.2 5.9 2.0 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain SET PF00856.28 KXH29477.1 - 1.5e-17 64.5 0.3 1.5e-17 64.5 0.3 3.2 2 2 0 2 2 2 1 SET domain AWS PF17907.1 KXH29477.1 - 3.3e-11 43.0 6.8 3.3e-11 43.0 6.8 2.4 2 0 0 2 2 2 1 AWS domain Med26 PF08711.11 KXH29477.1 - 2.3e-05 24.3 2.2 2.8e-05 24.0 0.4 2.1 2 0 0 2 2 2 1 TFIIS helical bundle-like domain WW PF00397.26 KXH29477.1 - 0.026 14.6 0.3 0.066 13.3 0.3 1.8 1 0 0 1 1 1 0 WW domain DUF445 PF04286.12 KXH29477.1 - 7.1 6.3 8.8 2.1 8.1 0.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF445) DUF2431 PF10354.9 KXH29478.1 - 1.2e-60 204.6 0.1 4.2e-60 202.8 0.1 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF2431) NapB PF03892.14 KXH29478.1 - 2.3 8.2 6.4 0.51 10.4 0.5 2.5 2 0 0 2 2 2 0 Nitrate reductase cytochrome c-type subunit (NapB) ThiF PF00899.21 KXH29480.1 - 4e-29 101.7 0.0 5.5e-29 101.2 0.0 1.1 1 0 0 1 1 1 1 ThiF family Rrn6 PF10214.9 KXH29480.1 - 2.3 6.6 0.0 2.3 6.6 0.0 1.9 1 1 0 2 2 2 0 RNA polymerase I-specific transcription-initiation factor DHFR_1 PF00186.19 KXH29482.1 - 1.6e-28 99.4 0.0 8.8e-28 97.0 0.0 2.3 1 1 0 1 1 1 1 Dihydrofolate reductase Ubiq_cyt_C_chap PF03981.12 KXH29483.1 - 3.2e-32 111.6 0.9 3.2e-32 111.6 0.9 1.8 2 1 1 3 3 3 1 Ubiquinol-cytochrome C chaperone ketoacyl-synt PF00109.26 KXH29484.1 - 3.6e-62 210.2 0.3 3.6e-62 210.2 0.3 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KXH29484.1 - 2.1e-35 121.3 2.6 2.3e-35 121.1 1.5 1.6 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 KXH29484.1 - 5.6e-06 25.9 0.5 1.6e-05 24.4 0.1 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain KAsynt_C_assoc PF16197.5 KXH29484.1 - 0.045 14.2 0.2 0.089 13.2 0.2 1.5 1 0 0 1 1 1 0 Ketoacyl-synthetase C-terminal extension OPT PF03169.15 KXH29485.1 - 4.9e-180 600.2 51.6 5.6e-180 600.0 51.6 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF4191 PF13829.6 KXH29485.1 - 0.79 9.0 3.6 0.27 10.6 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) Fungal_trans PF04082.18 KXH29486.1 - 2.4e-17 62.9 0.0 3.9e-17 62.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain HTH_AsnC-type PF13404.6 KXH29487.1 - 0.046 13.6 1.5 5.9 6.8 0.0 3.0 3 0 0 3 3 3 0 AsnC-type helix-turn-helix domain Annexin PF00191.20 KXH29491.1 - 1.4e-70 233.3 4.1 9.1e-19 67.3 0.2 4.3 4 0 0 4 4 4 4 Annexin Acetyltransf_11 PF13720.6 KXH29491.1 - 0.0031 17.9 1.8 18 5.9 0.0 4.0 4 0 0 4 4 4 1 Udp N-acetylglucosamine O-acyltransferase; Domain 2 DUF3574 PF12098.8 KXH29491.1 - 0.0042 16.9 1.0 4 7.3 0.1 3.7 4 0 0 4 4 4 1 Protein of unknown function (DUF3574) Minor_tail_Z PF06763.11 KXH29491.1 - 0.01 15.6 0.4 0.99 9.2 0.2 2.4 2 0 0 2 2 2 0 Prophage minor tail protein Z (GPZ) YqbF PF14553.6 KXH29491.1 - 0.04 13.8 0.8 8 6.4 0.0 3.0 3 0 0 3 3 3 0 YqbF, hypothetical protein domain DUF2255 PF10012.9 KXH29491.1 - 0.052 13.7 0.8 11 6.3 0.0 3.4 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2255) Myb_DNA-bind_7 PF15963.5 KXH29491.1 - 0.053 13.4 1.3 1.7 8.6 0.1 2.8 3 0 0 3 3 3 0 Myb DNA-binding like Spore_GerAC PF05504.11 KXH29491.1 - 0.22 11.7 0.5 3 8.1 0.2 2.3 2 1 0 2 2 2 0 Spore germination B3/ GerAC like, C-terminal YlbE PF14003.6 KXH29491.1 - 0.82 10.2 2.9 9.2 6.8 0.0 2.8 3 0 0 3 3 3 0 YlbE-like protein zf-C2H2_4 PF13894.6 KXH29492.1 - 0.066 14.1 0.1 0.17 12.8 0.1 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger FPP PF05911.11 KXH29503.1 - 0.00021 19.7 1.2 0.00028 19.3 1.2 1.1 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil Apolipoprotein PF01442.18 KXH29503.1 - 0.019 14.8 11.0 0.032 14.1 11.0 1.3 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Stathmin PF00836.19 KXH29503.1 - 0.027 14.4 1.7 0.051 13.5 1.7 1.3 1 0 0 1 1 1 0 Stathmin family IFT57 PF10498.9 KXH29503.1 - 0.038 13.0 3.7 0.058 12.4 3.7 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Exonuc_VII_L PF02601.15 KXH29503.1 - 0.039 13.5 4.1 0.057 13.0 4.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit NleF_casp_inhib PF16809.5 KXH29503.1 - 0.042 13.8 0.8 0.27 11.2 0.1 2.0 1 1 1 2 2 2 0 NleF caspase inhibitor DUF16 PF01519.16 KXH29503.1 - 0.06 13.8 8.8 0.66 10.5 8.8 2.2 1 1 0 1 1 1 0 Protein of unknown function DUF16 DUF773 PF05600.12 KXH29503.1 - 0.074 11.8 4.1 0.1 11.3 4.1 1.1 1 0 0 1 1 1 0 CDK5 regulatory subunit-associated protein 3 DUF5320 PF17253.2 KXH29503.1 - 0.077 14.1 0.1 0.47 11.5 0.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5320) HemX PF04375.14 KXH29503.1 - 0.086 12.1 3.1 0.14 11.4 3.1 1.2 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase MCPsignal PF00015.21 KXH29503.1 - 0.094 12.5 0.5 0.17 11.7 0.5 1.3 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF3584 PF12128.8 KXH29503.1 - 0.098 10.2 6.4 0.14 9.6 6.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA_13 PF13166.6 KXH29503.1 - 0.11 11.1 1.0 0.15 10.7 1.0 1.1 1 0 0 1 1 1 0 AAA domain Gp58 PF07902.11 KXH29503.1 - 0.11 10.7 4.6 0.16 10.3 4.6 1.1 1 0 0 1 1 1 0 gp58-like protein kleA_kleC PF17383.2 KXH29503.1 - 0.12 12.8 0.0 7.4 7.0 0.1 2.7 2 0 0 2 2 2 0 Uncharacterized KorC regulated protein A Nup54 PF13874.6 KXH29503.1 - 0.12 12.5 5.9 0.18 11.9 0.4 2.3 1 1 0 2 2 2 0 Nucleoporin complex subunit 54 Sec34 PF04136.15 KXH29503.1 - 0.12 12.2 1.8 0.27 11.1 1.8 1.6 1 0 0 1 1 1 0 Sec34-like family YkyA PF10368.9 KXH29503.1 - 0.12 12.0 3.3 0.27 10.9 3.3 1.5 1 1 0 1 1 1 0 Putative cell-wall binding lipoprotein APC_N_CC PF16689.5 KXH29503.1 - 0.16 12.0 2.2 0.43 10.7 2.2 1.7 1 0 0 1 1 1 0 Coiled-coil N-terminus of APC, dimerisation domain SKA1 PF07160.12 KXH29503.1 - 0.22 11.3 6.7 0.068 13.0 2.1 2.0 1 1 0 2 2 2 0 Spindle and kinetochore-associated protein 1 Spectrin PF00435.21 KXH29503.1 - 0.23 11.9 10.0 0.61 10.6 2.8 2.3 1 1 1 2 2 2 0 Spectrin repeat SlyX PF04102.12 KXH29503.1 - 0.3 11.7 7.1 3.7 8.2 0.6 3.2 3 0 0 3 3 3 0 SlyX ERM PF00769.19 KXH29503.1 - 0.33 10.7 8.6 0.5 10.1 8.6 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family TSC22 PF01166.18 KXH29503.1 - 0.46 10.8 6.8 0.67 10.3 0.6 2.9 2 1 0 2 2 2 0 TSC-22/dip/bun family Occludin_ELL PF07303.13 KXH29503.1 - 0.75 10.5 4.6 6.3 7.6 0.9 3.0 1 1 1 3 3 3 0 Occludin homology domain V-SNARE_C PF12352.8 KXH29503.1 - 0.8 10.0 5.0 4 7.8 1.7 2.6 1 1 1 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus Seryl_tRNA_N PF02403.22 KXH29503.1 - 0.8 10.0 5.8 6.3 7.1 0.3 2.6 1 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Fez1 PF06818.15 KXH29503.1 - 1 9.8 11.2 0.33 11.4 6.3 2.0 1 1 1 2 2 2 0 Fez1 PV-1 PF06637.11 KXH29503.1 - 1.1 8.0 5.9 0.4 9.5 2.8 1.7 2 0 0 2 2 2 0 PV-1 protein (PLVAP) Nup88 PF10168.9 KXH29503.1 - 1.2 6.9 5.2 1.6 6.5 5.2 1.1 1 0 0 1 1 1 0 Nuclear pore component Noelin-1 PF12308.8 KXH29503.1 - 1.4 8.9 3.6 1.3 9.0 1.0 2.3 1 1 1 2 2 1 0 Neurogenesis glycoprotein BLOC1_2 PF10046.9 KXH29503.1 - 1.4 9.2 5.1 2.3 8.6 0.1 2.8 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4763 PF15960.5 KXH29503.1 - 1.5 8.1 8.1 4.7 6.4 8.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4763) DUF1664 PF07889.12 KXH29503.1 - 1.9 8.5 5.1 17 5.4 5.1 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Laminin_II PF06009.12 KXH29503.1 - 1.9 8.5 5.9 7.5 6.6 1.5 2.3 1 1 1 2 2 2 0 Laminin Domain II CLZ PF16526.5 KXH29503.1 - 2 8.8 8.2 10 6.6 0.4 3.3 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Tropomyosin PF00261.20 KXH29503.1 - 2.3 7.5 13.2 1.9 7.8 2.5 2.2 1 1 1 2 2 2 0 Tropomyosin Tropomyosin_1 PF12718.7 KXH29503.1 - 2.6 8.2 16.9 1.5 9.0 1.6 2.2 1 1 0 2 2 2 0 Tropomyosin like Fib_alpha PF08702.10 KXH29503.1 - 3.8 7.7 5.1 13 6.0 5.1 1.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family MscS_porin PF12795.7 KXH29503.1 - 4.9 6.6 13.7 2.4 7.7 2.3 2.3 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain HrpB7 PF09486.10 KXH29503.1 - 5 7.5 10.8 2.6 8.4 2.1 2.3 1 1 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) Spc7 PF08317.11 KXH29503.1 - 5.6 5.8 10.7 9 5.1 2.6 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein CENP-F_leu_zip PF10473.9 KXH29503.1 - 5.6 7.0 14.8 0.76 9.8 7.5 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 KASH_CCD PF14662.6 KXH29503.1 - 6.2 6.6 12.5 25 4.6 12.5 1.8 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH 3-PAP PF12578.8 KXH29503.1 - 6.6 6.5 7.7 10 5.9 1.3 3.0 1 1 2 3 3 3 0 Myotubularin-associated protein Fmp27_WPPW PF10359.9 KXH29503.1 - 6.9 5.4 8.3 24 3.6 8.3 1.8 1 1 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Jnk-SapK_ap_N PF09744.9 KXH29503.1 - 7.8 6.7 12.9 4.3 7.6 10.4 1.7 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 GAS PF13851.6 KXH29503.1 - 8.2 5.7 11.4 4.7 6.5 4.5 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding OEP PF02321.18 KXH29503.1 - 9.3 6.0 9.5 1 9.2 1.4 2.2 2 0 0 2 2 2 0 Outer membrane efflux protein Csm1_N PF18504.1 KXH29503.1 - 9.8 6.6 8.2 4 7.8 0.3 3.0 2 1 1 3 3 3 0 Csm1 N-terminal domain NCBP3 PF10309.9 KXH29504.1 - 6.6e-23 80.3 0.0 1.1e-22 79.7 0.0 1.3 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 MFS_1 PF07690.16 KXH29613.1 - 1.2e-39 136.2 39.1 1.2e-39 136.2 39.1 2.0 1 1 2 3 3 3 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH29613.1 - 1.3e-12 47.3 11.8 1.3e-12 47.3 11.8 2.5 2 2 0 2 2 2 1 Sugar (and other) transporter Sugar_tr PF00083.24 KXH29614.1 - 2.7e-107 359.4 23.3 3.3e-107 359.2 23.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH29614.1 - 1.1e-19 70.6 29.9 1.1e-19 70.6 29.9 2.3 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF1324 PF07038.11 KXH29614.1 - 0.027 14.7 0.1 0.19 12.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1324) DUF4410 PF14366.6 KXH29614.1 - 0.11 12.4 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4410) Pkinase PF00069.25 KXH29615.1 - 6.3e-11 42.1 0.0 9.1e-07 28.5 0.0 2.5 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXH29615.1 - 8.1e-07 28.6 0.0 2.5e-06 27.0 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KXH29615.1 - 0.0045 16.3 0.0 0.0085 15.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Queuosine_synth PF02547.15 KXH29615.1 - 0.17 10.9 0.0 0.36 9.9 0.0 1.5 2 0 0 2 2 2 0 Queuosine biosynthesis protein Glyco_hydro_72 PF03198.14 KXH29617.1 - 3.3e-95 319.0 0.1 4.4e-95 318.5 0.1 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 KXH29617.1 - 0.0009 18.8 0.5 0.0043 16.5 0.5 2.0 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.17 KXH29617.1 - 0.0029 16.8 0.8 0.005 16.0 0.1 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain NAD_binding_2 PF03446.15 KXH29618.1 - 8.9e-20 71.5 0.0 1.4e-19 70.8 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 KXH29618.1 - 0.063 13.3 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase RGS PF00615.19 KXH29619.1 - 0.0046 17.2 0.0 0.0086 16.3 0.0 1.6 1 1 0 1 1 1 1 Regulator of G protein signaling domain TMEM43 PF07787.12 KXH29619.1 - 0.094 12.1 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 43 DUF2065 PF09838.9 KXH29619.1 - 0.15 12.1 0.1 0.15 12.1 0.1 2.5 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2065) Chorismate_bind PF00425.18 KXH29620.1 - 3.7e-90 302.0 0.0 1.5e-89 300.0 0.0 1.8 2 0 0 2 2 2 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 KXH29620.1 - 5.4e-26 91.5 0.0 2.7e-21 76.3 0.0 3.8 3 1 0 3 3 3 2 Anthranilate synthase component I, N terminal region Mycoplasma_p37 PF06646.11 KXH29620.1 - 0.15 11.2 0.1 0.33 10.1 0.0 1.6 2 0 0 2 2 2 0 High affinity transport system protein p37 Ribosomal_L3 PF00297.22 KXH29622.1 - 7.1e-180 597.8 9.8 8e-180 597.6 9.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 DUF1639 PF07797.14 KXH29622.1 - 0.23 11.4 1.0 0.79 9.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1639) TPR_1 PF00515.28 KXH29623.1 - 6.2e-54 177.7 31.6 6.4e-08 32.1 0.0 10.4 11 1 0 11 11 10 8 Tetratricopeptide repeat TPR_2 PF07719.17 KXH29623.1 - 9.7e-48 156.5 26.3 1.7e-06 27.7 0.0 10.3 11 0 0 11 11 10 9 Tetratricopeptide repeat TPR_8 PF13181.6 KXH29623.1 - 1.9e-39 130.5 24.6 3.2e-07 30.0 0.0 10.6 10 1 0 10 10 10 9 Tetratricopeptide repeat TPR_16 PF13432.6 KXH29623.1 - 2.2e-29 101.8 14.5 1.2e-07 32.2 0.0 6.5 3 2 2 6 6 6 6 Tetratricopeptide repeat TPR_14 PF13428.6 KXH29623.1 - 4.2e-28 95.6 16.9 4.9e-05 23.8 0.1 8.9 3 2 7 10 10 10 7 Tetratricopeptide repeat TPR_17 PF13431.6 KXH29623.1 - 1e-26 91.3 15.8 0.0024 18.1 0.0 10.1 11 0 0 11 11 10 6 Tetratricopeptide repeat TPR_11 PF13414.6 KXH29623.1 - 4.2e-25 87.1 28.7 3.7e-06 26.5 0.2 9.3 4 2 5 9 9 9 5 TPR repeat TPR_19 PF14559.6 KXH29623.1 - 7.4e-23 80.8 20.3 0.00017 22.0 0.1 6.9 4 2 3 7 7 7 6 Tetratricopeptide repeat TPR_12 PF13424.6 KXH29623.1 - 4.9e-22 78.0 24.5 4.6e-05 23.6 0.9 7.5 4 2 2 6 6 6 5 Tetratricopeptide repeat TPR_6 PF13174.6 KXH29623.1 - 1.4e-21 75.6 18.2 0.0014 19.1 0.0 9.5 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_7 PF13176.6 KXH29623.1 - 2.2e-17 61.7 16.9 0.01 15.8 0.1 9.5 8 1 1 9 9 9 3 Tetratricopeptide repeat TPR_9 PF13371.6 KXH29623.1 - 1.1e-15 57.5 16.9 0.0011 19.1 0.1 6.0 2 2 4 7 7 7 6 Tetratricopeptide repeat ANAPC3 PF12895.7 KXH29623.1 - 1.1e-14 54.4 12.2 1.5e-08 34.7 1.1 3.6 3 1 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 KXH29623.1 - 2.2e-11 43.5 12.0 0.0016 17.7 1.1 5.3 1 1 3 5 5 5 4 Tetratricopeptide repeat TPR_21 PF09976.9 KXH29623.1 - 3e-07 30.3 9.6 0.019 14.6 0.0 5.0 4 2 1 5 5 5 2 Tetratricopeptide repeat-like domain Fis1_TPR_C PF14853.6 KXH29623.1 - 0.00028 20.9 0.6 32 4.7 0.0 5.2 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat TPR_20 PF14561.6 KXH29623.1 - 0.0012 19.1 6.9 0.54 10.6 0.4 3.9 3 1 1 4 4 3 2 Tetratricopeptide repeat BTAD PF03704.17 KXH29623.1 - 0.011 16.1 0.4 0.011 16.1 0.4 3.9 3 1 0 4 4 3 0 Bacterial transcriptional activator domain TPR_10 PF13374.6 KXH29623.1 - 0.013 15.4 21.3 4 7.4 0.0 7.7 8 0 0 8 8 8 0 Tetratricopeptide repeat DUF2225 PF09986.9 KXH29623.1 - 0.016 14.9 1.9 1.5 8.5 0.1 3.3 1 1 2 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) RPN7 PF10602.9 KXH29623.1 - 0.41 10.3 6.1 1.4 8.6 0.2 4.1 5 1 1 6 6 6 0 26S proteasome subunit RPN7 Cohesin_load PF10345.9 KXH29623.1 - 0.52 8.7 2.4 18 3.6 0.2 2.8 2 1 1 3 3 3 0 Cohesin loading factor SNAP PF14938.6 KXH29623.1 - 0.86 9.0 17.4 9.1 5.6 1.7 4.8 1 1 3 4 4 4 0 Soluble NSF attachment protein, SNAP DUF1751 PF08551.10 KXH29625.1 - 9.3e-27 93.5 4.2 2.2e-26 92.3 4.2 1.6 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.22 KXH29625.1 - 0.33 10.9 9.0 0.71 9.9 9.0 1.5 1 0 0 1 1 1 0 Rhomboid family DIM1 PF02966.16 KXH29628.1 - 2.3e-27 95.4 0.1 2.5e-27 95.3 0.1 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 MOR2-PAG1_N PF14222.6 KXH29629.1 - 4.9e-222 738.8 0.0 7.3e-222 738.2 0.0 1.3 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.6 KXH29629.1 - 1.2e-92 310.4 1.2 1.7e-92 309.8 0.1 1.9 2 0 0 2 2 2 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.6 KXH29629.1 - 5.4e-39 133.6 7.2 3.3e-18 64.8 0.1 3.4 2 1 1 3 3 3 3 Cell morphogenesis central region HEAT_2 PF13646.6 KXH29629.1 - 0.14 12.6 0.3 37 4.8 0.0 4.8 5 1 0 5 5 5 0 HEAT repeats FAD_binding_1 PF00667.20 KXH29631.1 - 6.8e-61 205.7 0.0 1e-60 205.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KXH29631.1 - 2.9e-32 111.8 0.6 6.5e-32 110.7 0.6 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 KXH29631.1 - 4.1e-19 69.2 0.0 1.5e-18 67.4 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 KXH29631.1 - 0.089 13.0 0.1 0.32 11.2 0.0 2.0 2 0 0 2 2 2 0 Flavodoxin domain MRFAP1 PF15155.6 KXH29638.1 - 0.043 14.3 0.4 0.043 14.3 0.4 1.0 1 0 0 1 1 1 0 MORF4 family-associated protein1 Mg_trans_NIPA PF05653.14 KXH29640.1 - 3e-62 210.4 8.0 1.8e-59 201.3 5.3 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 KXH29640.1 - 0.002 18.3 1.9 0.002 18.3 1.9 4.1 3 1 1 4 4 4 2 EamA-like transporter family SLC35F PF06027.12 KXH29640.1 - 0.021 14.4 2.8 1 8.8 0.0 2.3 2 0 0 2 2 2 0 Solute carrier family 35 DUF1461 PF07314.11 KXH29640.1 - 0.83 9.5 6.0 1.1 9.2 2.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1461) TssN PF17555.2 KXH29640.1 - 2.6 7.3 6.9 6.2 6.1 7.1 1.5 1 1 0 1 1 1 0 Type VI secretion system, TssN RRM_1 PF00076.22 KXH29641.1 - 9.5e-57 188.7 0.0 9.7e-17 60.6 0.0 5.6 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 KXH29641.1 - 1.1e-05 25.3 0.6 0.3 10.9 0.2 3.5 2 1 1 3 3 3 2 Rrp7 RRM-like N-terminal domain RRM_7 PF16367.5 KXH29641.1 - 0.0092 16.1 0.0 1.8 8.7 0.0 3.5 3 0 0 3 3 3 1 RNA recognition motif Cnd3 PF12719.7 KXH29642.1 - 6.8e-91 304.5 2.4 6.8e-91 304.5 2.4 2.1 3 1 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.6 KXH29642.1 - 3.9e-09 36.8 8.8 4e-05 23.9 1.0 4.6 4 0 0 4 4 4 2 HEAT repeats HEAT PF02985.22 KXH29642.1 - 3e-07 30.1 11.3 0.089 13.1 0.0 8.3 9 0 0 9 9 9 1 HEAT repeat Cnd1 PF12717.7 KXH29642.1 - 0.00074 19.6 5.7 0.4 10.7 0.1 4.5 4 1 1 5 5 5 3 non-SMC mitotic condensation complex subunit 1 DUF3069 PF11269.8 KXH29642.1 - 0.13 12.5 0.4 1.7 8.9 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3069) HEAT_EZ PF13513.6 KXH29642.1 - 9.9 6.8 15.4 0.81 10.3 0.7 5.3 6 1 1 7 7 7 0 HEAT-like repeat Phosphodiest PF01663.22 KXH29643.1 - 6.6e-10 39.1 3.0 2e-07 30.9 3.0 2.2 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KXH29643.1 - 0.00016 21.2 0.0 0.00094 18.7 0.0 1.9 2 0 0 2 2 2 1 Sulfatase DUF2423 PF10338.9 KXH29644.1 - 3e-20 72.2 3.7 3e-20 72.2 3.7 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2423) DUF3982 PF13138.6 KXH29644.1 - 0.065 13.0 0.1 0.11 12.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3982) PINIT PF14324.6 KXH29645.1 - 1.7e-43 148.5 0.1 3.2e-43 147.6 0.1 1.5 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.20 KXH29645.1 - 7e-23 80.1 5.9 1.7e-22 78.9 5.9 1.7 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 KXH29645.1 - 3e-06 26.9 1.6 6.5e-06 25.9 1.6 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit SAP PF02037.27 KXH29645.1 - 0.00032 20.4 0.0 0.0007 19.3 0.0 1.5 1 0 0 1 1 1 1 SAP domain zf-Sec23_Sec24 PF04810.15 KXH29645.1 - 0.048 13.7 1.7 0.14 12.2 0.8 2.3 2 1 0 2 2 2 0 Sec23/Sec24 zinc finger zf-C3HC4_4 PF15227.6 KXH29645.1 - 0.049 13.8 5.7 0.096 12.9 5.7 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Abhydrolase_9_N PF15420.6 KXH29645.1 - 0.11 12.4 0.2 0.19 11.7 0.2 1.2 1 0 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus zf-RING_5 PF14634.6 KXH29645.1 - 0.68 9.9 3.2 1.2 9.1 3.2 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.6 KXH29645.1 - 0.97 9.8 4.7 1.9 8.9 4.7 1.5 1 0 0 1 1 1 0 Ring finger domain TRAPP PF04051.16 KXH29646.1 - 2.3e-35 121.4 0.0 8e-25 87.3 0.0 2.1 1 1 1 2 2 2 2 Transport protein particle (TRAPP) component PorB PF11565.8 KXH29646.1 - 0.012 16.0 0.0 0.023 15.1 0.0 1.4 1 0 0 1 1 1 0 Alpha helical Porin B Rod_cone_degen PF15201.6 KXH29646.1 - 0.29 11.3 1.2 1.1 9.4 0.4 2.2 2 0 0 2 2 2 0 Progressive rod-cone degeneration Ldh_1_C PF02866.18 KXH29647.1 - 5.5e-50 169.6 0.0 7.7e-50 169.1 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 KXH29647.1 - 4.2e-44 150.1 0.2 6.1e-44 149.5 0.2 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KXH29647.1 - 0.0012 17.9 0.0 0.0018 17.4 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Ribosomal_L28e PF01778.17 KXH29648.1 - 1e-33 116.5 0.1 1.3e-33 116.2 0.1 1.1 1 0 0 1 1 1 1 Ribosomal L28e protein family DUF2015 PF09435.10 KXH29649.1 - 1.1e-47 160.5 0.0 1.2e-47 160.3 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) FA_hydroxylase PF04116.13 KXH29650.1 - 1.3e-24 87.1 15.5 1.3e-24 87.1 15.5 2.4 2 1 0 2 2 2 2 Fatty acid hydroxylase superfamily DUF5543 PF17697.1 KXH29650.1 - 0.19 12.0 0.0 0.34 11.2 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5543) MMtag PF10159.9 KXH29650.1 - 0.19 12.0 0.9 0.36 11.2 0.9 1.3 1 0 0 1 1 1 0 Multiple myeloma tumor-associated Tup_N PF08581.10 KXH29651.1 - 6.4e-18 64.8 12.8 1.3e-17 63.8 12.8 1.5 1 1 0 1 1 1 1 Tup N-terminal Golgin_A5 PF09787.9 KXH29651.1 - 0.00085 18.9 3.1 0.001 18.6 3.1 1.0 1 0 0 1 1 1 1 Golgin subfamily A member 5 Filament PF00038.21 KXH29651.1 - 0.0017 18.0 2.3 0.0022 17.6 2.3 1.1 1 0 0 1 1 1 1 Intermediate filament protein BBP1_C PF15272.6 KXH29651.1 - 0.0039 17.0 0.0 0.0044 16.9 0.0 1.0 1 0 0 1 1 1 1 Spindle pole body component BBP1, C-terminal LXG PF04740.12 KXH29651.1 - 0.0064 16.2 1.9 0.0083 15.9 1.9 1.1 1 0 0 1 1 1 1 LXG domain of WXG superfamily SHE3 PF17078.5 KXH29651.1 - 0.008 15.9 3.8 0.01 15.6 3.8 1.1 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 Tektin PF03148.14 KXH29651.1 - 0.01 14.6 3.0 0.012 14.3 3.0 1.0 1 0 0 1 1 1 0 Tektin family TSNAXIP1_N PF15739.5 KXH29651.1 - 0.035 14.5 4.8 0.047 14.1 4.8 1.1 1 0 0 1 1 1 0 Translin-associated factor X-interacting N-terminus TPX2 PF06886.11 KXH29651.1 - 0.065 13.5 10.7 5.1 7.4 10.7 2.1 1 1 0 1 1 1 0 Targeting protein for Xklp2 (TPX2) Fib_alpha PF08702.10 KXH29651.1 - 0.15 12.3 2.4 0.19 11.9 2.4 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family USP8_interact PF08941.10 KXH29651.1 - 0.27 11.0 4.0 0.33 10.7 4.0 1.1 1 0 0 1 1 1 0 USP8 interacting Zn_clus PF00172.18 KXH29678.1 - 1.1e-05 25.5 10.4 2.3e-05 24.4 10.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldedh PF00171.22 KXH29680.1 - 3.1e-137 457.8 1.7 3.8e-137 457.6 1.7 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family tRNA-synt_2b PF00587.25 KXH29681.1 - 5.7e-36 124.2 0.0 3e-32 112.0 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KXH29681.1 - 1.3e-08 34.9 0.0 2.5e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain HLH PF00010.26 KXH29682.1 - 6.4e-09 35.6 0.0 1.1e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Umbravirus_LDM PF04817.12 KXH29682.1 - 0.0071 15.7 0.1 0.0083 15.5 0.1 1.1 1 0 0 1 1 1 1 Umbravirus long distance movement (LDM) family DUF3006 PF11213.8 KXH29682.1 - 0.92 9.8 4.3 15 5.9 0.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3006) Maf PF02545.14 KXH29683.1 - 6.7e-51 172.4 0.0 7.9e-51 172.2 0.0 1.1 1 0 0 1 1 1 1 Maf-like protein Glyco_hydro_47 PF01532.20 KXH29684.1 - 9.4e-174 578.6 0.2 1.1e-173 578.4 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_127 PF07944.12 KXH29684.1 - 0.028 12.9 0.2 0.81 8.1 0.1 2.4 2 1 0 2 2 2 0 Beta-L-arabinofuranosidase, GH127 Utp11 PF03998.13 KXH29685.1 - 2.5e-65 220.9 16.2 2.8e-65 220.7 16.2 1.0 1 0 0 1 1 1 1 Utp11 protein SLATT_5 PF18160.1 KXH29685.1 - 0.96 8.7 3.1 0.3 10.4 0.2 1.6 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 UPF0242 PF06785.11 KXH29685.1 - 1 9.4 6.9 0.29 11.2 2.0 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF3246 PF11596.8 KXH29685.1 - 1.5 8.2 5.9 0.51 9.7 3.1 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3246) DUF4407 PF14362.6 KXH29685.1 - 1.6 8.0 11.3 0.21 10.9 6.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DAO PF01266.24 KXH29687.1 - 7.2e-28 98.2 0.0 1.3e-27 97.4 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_N PF05222.15 KXH29687.1 - 6.2e-27 94.6 0.0 1.6e-26 93.2 0.0 1.7 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.21 KXH29687.1 - 1.1e-08 34.7 0.1 0.0017 17.7 0.0 3.1 2 1 1 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 KXH29687.1 - 9.4e-06 24.9 0.1 1.5e-05 24.3 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KXH29687.1 - 0.00039 20.6 0.6 0.0017 18.5 0.4 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXH29687.1 - 0.0013 18.1 1.1 0.0013 18.0 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 KXH29687.1 - 0.0014 18.3 0.0 0.012 15.3 0.0 2.2 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.27 KXH29687.1 - 0.0033 18.0 0.0 0.0087 16.6 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.17 KXH29687.1 - 0.0058 17.2 0.3 0.48 11.0 0.0 3.1 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent UDPG_MGDP_dh_N PF03721.14 KXH29687.1 - 0.0084 15.7 0.5 0.018 14.7 0.5 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_7 PF13241.6 KXH29687.1 - 0.014 15.8 0.0 0.032 14.7 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding 3HCDH_N PF02737.18 KXH29687.1 - 0.016 15.1 0.1 0.085 12.7 0.0 2.0 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 KXH29687.1 - 0.02 14.2 0.0 0.033 13.4 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Sacchrp_dh_NADP PF03435.18 KXH29687.1 - 0.022 15.0 0.5 5.8 7.2 0.1 2.6 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain GIDA PF01134.22 KXH29687.1 - 0.05 12.7 0.0 0.05 12.7 0.0 1.5 2 0 0 2 2 2 0 Glucose inhibited division protein A HI0933_like PF03486.14 KXH29687.1 - 0.076 11.7 0.4 0.11 11.1 0.4 1.2 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.17 KXH29687.1 - 0.078 12.2 0.2 0.17 11.1 0.2 1.5 1 0 0 1 1 1 0 Thi4 family 2-Hacid_dh_C PF02826.19 KXH29687.1 - 0.097 12.0 0.0 1.3 8.3 0.0 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Epimerase PF01370.21 KXH29687.1 - 0.099 12.1 0.0 5.7 6.3 0.0 2.2 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Pyr_redox_3 PF13738.6 KXH29687.1 - 0.13 11.5 0.1 0.13 11.5 0.1 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 KXH29687.1 - 0.14 12.5 0.4 0.42 10.9 0.0 2.0 2 0 0 2 2 2 0 TrkA-N domain DapB_N PF01113.20 KXH29687.1 - 0.17 12.0 0.2 2.4 8.3 0.0 2.3 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Cmc1 PF08583.10 KXH29688.1 - 3.7e-11 42.9 0.3 3.7e-11 42.9 0.3 2.6 3 0 0 3 3 3 1 Cytochrome c oxidase biogenesis protein Cmc1 like fn3 PF00041.21 KXH29689.1 - 4.6e-08 33.3 0.0 1.3e-07 31.8 0.0 1.8 1 0 0 1 1 1 1 Fibronectin type III domain UDPGP PF01704.18 KXH29690.1 - 7.2e-56 189.6 0.0 9e-56 189.3 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.7 KXH29690.1 - 0.016 15.6 0.0 0.056 13.8 0.0 1.9 2 0 0 2 2 2 0 MobA-like NTP transferase domain LNS2 PF08235.13 KXH29691.1 - 1.8e-92 308.9 0.0 2.4e-92 308.5 0.0 1.1 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 KXH29691.1 - 1.8e-42 143.4 0.0 1e-41 141.0 0.0 2.1 2 0 0 2 2 2 1 lipin, N-terminal conserved region Acid_phosphat_B PF03767.14 KXH29691.1 - 0.0041 16.7 0.3 0.18 11.3 0.0 2.7 3 0 0 3 3 3 1 HAD superfamily, subfamily IIIB (Acid phosphatase) TFIID-31kDa PF02291.15 KXH29692.1 - 3.5e-42 143.3 0.0 5e-42 142.8 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit FDF PF09532.10 KXH29692.1 - 0.027 15.3 0.9 0.053 14.4 0.1 1.9 2 0 0 2 2 2 0 FDF domain Spt20 PF12090.8 KXH29692.1 - 0.063 12.9 14.7 0.087 12.4 14.7 1.3 1 0 0 1 1 1 0 Spt20 family Presenilin PF01080.17 KXH29692.1 - 0.32 9.7 6.0 0.42 9.3 6.0 1.3 1 0 0 1 1 1 0 Presenilin Ndc1_Nup PF09531.10 KXH29692.1 - 1.7 7.2 8.1 1.7 7.3 8.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Macoilin PF09726.9 KXH29692.1 - 1.9 7.0 6.7 2.3 6.7 6.7 1.1 1 0 0 1 1 1 0 Macoilin family Pex14_N PF04695.13 KXH29692.1 - 2.6 8.7 23.7 4.2 8.0 23.7 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PAT1 PF09770.9 KXH29692.1 - 4.1 5.6 11.2 4.6 5.4 11.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 ORC6 PF05460.13 KXH29692.1 - 5.7 6.1 13.9 8.3 5.6 13.9 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Histidinol_dh PF00815.20 KXH29693.1 - 3.8e-158 526.8 4.4 5e-158 526.4 4.4 1.2 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.18 KXH29693.1 - 1.2e-24 85.9 0.1 2.5e-24 84.9 0.1 1.5 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.17 KXH29693.1 - 3.5e-13 49.8 0.9 6.4e-13 49.0 0.2 1.9 2 0 0 2 2 2 1 Phosphoribosyl-ATP pyrophosphohydrolase Phasin_2 PF09361.10 KXH29693.1 - 0.074 13.3 3.1 0.44 10.8 0.3 3.1 3 0 0 3 3 3 0 Phasin protein Peptidase_M16 PF00675.20 KXH29694.1 - 1.1e-56 190.9 0.5 2.9e-56 189.6 0.5 1.7 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KXH29694.1 - 1.3e-37 129.5 0.0 9.1e-37 126.8 0.0 2.0 2 0 0 2 2 2 1 Peptidase M16 inactive domain Esterase PF00756.20 KXH29694.1 - 0.0041 16.8 0.0 0.0083 15.8 0.0 1.5 1 0 0 1 1 1 1 Putative esterase Raffinose_syn PF05691.12 KXH29695.1 - 1.6e-56 191.6 5.7 7e-50 169.6 4.6 3.1 2 1 0 2 2 2 2 Raffinose synthase or seed imbibition protein Sip1 Glyco_hydro_31 PF01055.26 KXH29695.1 - 1.6e-07 30.9 1.0 2.4e-07 30.3 1.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Epimerase PF01370.21 KXH29696.1 - 5.3e-09 35.9 0.0 0.0012 18.4 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KXH29696.1 - 7.2e-08 32.5 0.0 1.6e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 KXH29696.1 - 0.00066 20.1 0.0 0.0014 19.0 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.13 KXH29696.1 - 0.0099 15.5 0.0 0.024 14.2 0.0 1.6 2 0 0 2 2 2 1 NmrA-like family Pribosyltran PF00156.27 KXH29697.1 - 9.7e-15 54.4 0.0 1.6e-14 53.8 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KXH29697.1 - 0.0016 17.9 0.0 0.0022 17.4 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Nop PF01798.18 KXH29699.1 - 5.8e-72 241.9 0.0 8.5e-72 241.3 0.0 1.2 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 KXH29699.1 - 1.5e-46 158.2 3.2 2.9e-46 157.3 2.4 1.9 2 0 0 2 2 2 1 Prp31 C terminal domain HAT PF02184.16 KXH29700.1 - 1.7e-23 82.3 71.5 3.6e-12 46.0 2.9 12.9 15 0 0 15 15 14 4 HAT (Half-A-TPR) repeat TPR_14 PF13428.6 KXH29700.1 - 1e-20 72.6 24.8 0.0003 21.4 0.1 10.3 9 2 3 12 12 10 6 Tetratricopeptide repeat TPR_19 PF14559.6 KXH29700.1 - 1.9e-17 63.5 2.6 4.1e-05 24.0 0.0 6.3 6 1 2 8 8 7 2 Tetratricopeptide repeat Suf PF05843.14 KXH29700.1 - 6.3e-17 62.5 22.3 3.2e-06 27.3 0.1 6.4 3 1 3 6 6 6 4 Suppressor of forked protein (Suf) TPR_8 PF13181.6 KXH29700.1 - 1.4e-06 28.0 3.1 0.33 11.3 0.0 6.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_15 PF13429.6 KXH29700.1 - 5.4e-06 25.8 12.2 0.86 8.8 0.1 5.9 2 1 4 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 KXH29700.1 - 5.6e-06 26.1 13.5 0.25 11.6 0.1 7.4 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_16 PF13432.6 KXH29700.1 - 4e-05 24.2 11.8 0.66 10.7 0.0 7.1 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_17 PF13431.6 KXH29700.1 - 0.0017 18.6 11.7 3.1 8.4 0.0 7.3 8 0 0 8 8 7 1 Tetratricopeptide repeat U3_assoc_6 PF08640.11 KXH29700.1 - 0.0031 17.5 29.9 0.052 13.6 0.6 7.8 6 2 2 8 8 8 2 U3 small nucleolar RNA-associated protein 6 Tnp_22_trimer PF17489.2 KXH29700.1 - 0.0058 16.6 0.2 0.016 15.1 0.2 1.8 1 0 0 1 1 1 1 L1 transposable element trimerization domain BSD PF03909.17 KXH29700.1 - 0.0074 16.3 0.7 0.047 13.7 0.2 2.7 2 1 0 2 2 2 1 BSD domain TPR_9 PF13371.6 KXH29700.1 - 0.02 15.1 9.0 0.85 9.8 0.0 4.9 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 KXH29700.1 - 0.048 13.5 2.8 26 4.8 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat NRDE-2 PF08424.10 KXH29700.1 - 0.05 12.7 25.7 0.64 9.1 2.6 5.6 4 3 2 6 6 6 0 NRDE-2, necessary for RNA interference TPR_6 PF13174.6 KXH29700.1 - 0.089 13.5 26.7 1.6 9.6 0.0 8.3 10 0 0 10 10 7 0 Tetratricopeptide repeat TPR_12 PF13424.6 KXH29700.1 - 0.11 12.9 16.5 3.1 8.1 0.0 7.2 9 0 0 9 9 7 0 Tetratricopeptide repeat c-SKI_SMAD_bind PF08782.10 KXH29700.1 - 0.13 12.5 3.3 2.2 8.5 0.1 3.7 3 0 0 3 3 3 0 c-SKI Smad4 binding domain Fis1_TPR_C PF14853.6 KXH29700.1 - 0.25 11.5 8.3 12 6.0 0.3 5.4 6 0 0 6 6 5 0 Fis1 C-terminal tetratricopeptide repeat ER PF01133.17 KXH29700.1 - 0.54 10.3 4.2 37 4.4 0.0 3.9 3 1 1 4 4 4 0 Enhancer of rudimentary Pam16 PF03656.13 KXH29702.1 - 2.4 8.2 4.0 5.8 6.9 4.0 1.6 1 0 0 1 1 1 0 Pam16 CRAL_TRIO PF00650.20 KXH29705.1 - 1.9e-35 121.9 0.0 3e-35 121.3 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KXH29705.1 - 6.6e-08 32.6 0.4 1.7e-07 31.3 0.0 2.0 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KXH29705.1 - 0.0057 16.8 0.0 0.015 15.5 0.0 1.6 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain DUF1769 PF08588.10 KXH29705.1 - 0.12 12.6 0.0 0.24 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1769) Prefoldin PF02996.17 KXH29706.1 - 6.2e-35 119.7 0.1 1e-34 119.0 0.1 1.4 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.20 KXH29706.1 - 0.00057 19.8 5.0 0.002 18.0 0.0 2.9 3 1 1 4 4 4 1 Prefoldin subunit FlaC_arch PF05377.11 KXH29706.1 - 0.006 16.9 0.9 0.14 12.6 0.1 2.5 2 1 0 2 2 2 1 Flagella accessory protein C (FlaC) End3 PF12761.7 KXH29706.1 - 0.048 13.8 1.5 0.14 12.3 0.6 2.2 1 1 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 Lebercilin PF15619.6 KXH29706.1 - 0.57 9.8 6.3 0.79 9.3 2.5 2.0 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Mito_carr PF00153.27 KXH29707.1 - 2.5e-58 194.0 2.0 1.3e-20 73.1 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein RINT1_TIP1 PF04437.13 KXH29708.1 - 3.4e-182 606.8 0.1 9.6e-182 605.3 0.0 1.7 2 0 0 2 2 2 1 RINT-1 / TIP-1 family Zwint PF15556.6 KXH29708.1 - 0.025 14.1 7.4 0.055 13.0 7.4 1.6 1 0 0 1 1 1 0 ZW10 interactor CRISPR_Cse2 PF09485.10 KXH29708.1 - 0.031 14.8 3.5 0.073 13.6 2.3 2.3 2 0 0 2 2 2 0 CRISPR-associated protein Cse2 (CRISPR_cse2) DUF4164 PF13747.6 KXH29708.1 - 0.23 11.8 9.5 0.23 11.8 4.9 3.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) DUF883 PF05957.13 KXH29708.1 - 0.26 11.9 7.2 13 6.4 0.3 3.9 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF883) Atg14 PF10186.9 KXH29708.1 - 0.85 8.6 8.4 1.7 7.7 8.4 1.4 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF1664 PF07889.12 KXH29708.1 - 1.7 8.7 4.7 6.6 6.8 2.7 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) COG2 PF06148.11 KXH29708.1 - 9.1 6.4 7.1 28 4.8 0.4 3.5 3 1 1 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 Fig1 PF12351.8 KXH29709.1 - 2.5e-57 193.9 2.6 2.5e-57 193.9 2.6 2.0 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.12 KXH29709.1 - 1.2e-05 25.1 12.3 1.5e-05 24.8 11.8 1.4 1 1 0 1 1 1 1 SUR7/PalI family DUF898 PF05987.13 KXH29709.1 - 0.0017 17.5 10.3 0.0031 16.6 9.9 1.6 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF898) Glyco_hydro_47 PF01532.20 KXH29710.1 - 6e-185 615.5 0.0 7.9e-185 615.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 SARAF PF06682.12 KXH29710.1 - 2.5 7.7 8.6 0.055 13.1 0.9 2.0 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis NAD_binding_10 PF13460.6 KXH29711.1 - 1.1e-07 32.0 0.0 0.00035 20.5 0.0 2.2 2 0 0 2 2 2 2 NAD(P)H-binding Epimerase PF01370.21 KXH29711.1 - 0.00074 19.1 0.0 0.0011 18.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KXH29711.1 - 0.028 14.0 0.0 0.057 13.0 0.0 1.5 2 0 0 2 2 2 0 NmrA-like family NTPase_1 PF03266.15 KXH29711.1 - 0.11 12.3 0.0 0.25 11.2 0.0 1.5 2 0 0 2 2 2 0 NTPase GDP_Man_Dehyd PF16363.5 KXH29711.1 - 0.13 11.6 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase SOR_SNZ PF01680.17 KXH29713.1 - 4.7e-103 343.4 6.9 6.2e-103 343.0 6.9 1.1 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.14 KXH29713.1 - 2.7e-10 40.0 3.7 3e-07 30.0 0.1 2.4 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 KXH29713.1 - 0.0011 18.5 0.4 0.17 11.3 0.1 3.1 2 1 0 2 2 2 1 Histidine biosynthesis protein Dus PF01207.17 KXH29713.1 - 0.0036 16.5 2.7 0.48 9.5 0.1 2.6 3 1 0 3 3 3 2 Dihydrouridine synthase (Dus) TetR_C_27 PF17935.1 KXH29713.1 - 0.0057 16.7 0.0 0.015 15.3 0.0 1.7 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain IGPS PF00218.21 KXH29713.1 - 0.0078 15.4 0.3 0.1 11.8 0.0 2.5 2 1 0 2 2 2 1 Indole-3-glycerol phosphate synthase NanE PF04131.14 KXH29713.1 - 0.015 14.5 0.7 0.25 10.5 0.0 2.5 2 1 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase NMO PF03060.15 KXH29713.1 - 0.24 10.8 9.0 0.14 11.5 1.5 2.2 2 0 0 2 2 2 0 Nitronate monooxygenase WD40 PF00400.32 KXH29715.1 - 1.6e-11 44.5 2.4 0.0098 16.7 0.1 4.6 4 0 0 4 4 4 4 WD domain, G-beta repeat WD40_like PF17005.5 KXH29715.1 - 0.0018 17.7 0.0 0.004 16.5 0.0 1.5 2 0 0 2 2 2 1 WD40-like domain PQQ_3 PF13570.6 KXH29715.1 - 0.067 13.7 0.3 12 6.5 0.0 3.7 4 0 0 4 4 4 0 PQQ-like domain Nup160 PF11715.8 KXH29715.1 - 0.14 10.8 0.0 8.3 4.9 0.0 2.1 2 0 0 2 2 2 0 Nucleoporin Nup120/160 DUF3237 PF11578.8 KXH29716.1 - 3.8e-37 127.4 0.1 5.1e-37 127.0 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) GRAM PF02893.20 KXH29717.1 - 1e-31 109.1 1.4 9.9e-20 70.5 0.0 3.4 3 0 0 3 3 3 3 GRAM domain Glyco_transf_28 PF03033.20 KXH29717.1 - 3e-30 105.1 0.0 1e-29 103.3 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase family 28 N-terminal domain PH PF00169.29 KXH29717.1 - 6.1e-15 55.6 0.0 2.3e-14 53.8 0.0 2.1 2 0 0 2 2 2 1 PH domain PH_11 PF15413.6 KXH29717.1 - 3.2e-06 27.5 1.3 4.4e-05 23.9 1.3 2.6 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 KXH29717.1 - 6.1e-05 23.2 0.2 0.00022 21.4 0.0 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain UDPGT PF00201.18 KXH29717.1 - 0.00033 19.6 0.0 0.00058 18.8 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase NIF PF03031.18 KXH29718.1 - 9.3e-28 97.0 0.1 5.3e-27 94.5 0.0 2.0 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase BRCT PF00533.26 KXH29718.1 - 1.7e-07 31.5 0.1 8.5e-07 29.3 0.0 2.1 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 KXH29718.1 - 1.6e-05 24.8 0.0 5.5e-05 23.0 0.0 1.9 1 0 0 1 1 1 1 twin BRCT domain RTT107_BRCT_5 PF16770.5 KXH29718.1 - 0.0024 17.7 0.1 0.0072 16.2 0.0 1.8 2 0 0 2 2 2 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT_2 PF16589.5 KXH29718.1 - 0.0055 17.1 0.0 0.013 15.9 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT_3 PF18428.1 KXH29718.1 - 0.039 14.0 0.9 0.11 12.6 0.9 1.7 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 KXH29718.1 - 0.12 12.7 0.1 0.31 11.4 0.1 1.7 1 0 0 1 1 1 0 DNA ligase 3 BRCT domain GRIM-19 PF06212.12 KXH29719.1 - 2.2e-24 85.9 0.3 6.9e-24 84.3 0.3 1.6 1 1 0 1 1 1 1 GRIM-19 protein FAD_binding_3 PF01494.19 KXH29720.1 - 7.6e-25 87.9 0.3 2.9e-15 56.4 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 KXH29720.1 - 2e-08 33.9 0.8 0.00071 18.9 0.1 2.2 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXH29720.1 - 9e-08 32.1 1.0 0.0019 17.9 0.4 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXH29720.1 - 2.6e-07 30.8 0.4 1e-06 28.8 0.3 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 KXH29720.1 - 9.5e-06 24.7 0.8 0.0017 17.3 0.1 2.3 3 0 0 3 3 3 2 Tryptophan halogenase HI0933_like PF03486.14 KXH29720.1 - 1.1e-05 24.4 0.2 0.00045 19.0 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.6 KXH29720.1 - 1.4e-05 24.6 0.2 0.0054 16.0 0.1 2.5 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KXH29720.1 - 3.8e-05 23.2 0.2 5.7e-05 22.6 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KXH29720.1 - 0.0001 22.8 0.2 0.0011 19.5 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KXH29720.1 - 0.00049 19.5 0.2 0.33 10.2 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 KXH29720.1 - 0.00072 18.7 0.6 0.00072 18.7 0.6 2.2 3 0 0 3 3 3 1 FAD binding domain Lycopene_cycl PF05834.12 KXH29720.1 - 0.0009 18.4 0.1 0.002 17.2 0.1 1.5 1 1 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 KXH29720.1 - 0.0015 17.8 0.1 0.0026 17.0 0.1 1.3 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.22 KXH29720.1 - 0.0031 16.7 0.8 0.0058 15.8 0.8 1.5 1 1 0 1 1 1 1 Glucose inhibited division protein A ApbA PF02558.16 KXH29720.1 - 0.0072 16.0 0.1 0.013 15.1 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_9 PF13454.6 KXH29720.1 - 0.011 15.7 0.4 2.4 8.1 0.1 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding 3HCDH_N PF02737.18 KXH29720.1 - 0.071 13.0 0.1 0.13 12.1 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KXH29720.1 - 0.16 12.0 0.0 0.28 11.2 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 KXH29720.1 - 0.17 12.4 0.0 0.33 11.4 0.0 1.5 1 1 0 1 1 1 0 Putative NAD(P)-binding Bac_rhamnosid_C PF17390.2 KXH29721.1 - 8.5e-16 57.5 0.1 2.5e-15 56.0 0.1 1.8 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain Bac_rhamnosid6H PF17389.2 KXH29721.1 - 3e-06 26.7 0.0 6e-05 22.5 0.0 2.1 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain DUF1080 PF06439.11 KXH29721.1 - 0.085 12.9 0.0 0.41 10.7 0.0 2.0 2 1 0 2 2 2 0 Domain of Unknown Function (DUF1080) Pab87_oct PF13969.6 KXH29721.1 - 0.19 11.8 0.0 0.44 10.7 0.0 1.5 1 0 0 1 1 1 0 Pab87 octamerisation domain Cnd1_N PF12922.7 KXH29722.1 - 4.3e-63 212.1 0.1 4.9e-62 208.7 0.0 2.5 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1, N-term Cnd1 PF12717.7 KXH29722.1 - 2.2e-48 164.3 7.1 7.5e-45 152.9 0.2 3.2 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KXH29722.1 - 6.2e-10 38.5 3.0 0.017 15.3 0.0 6.2 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.6 KXH29722.1 - 3.4e-09 37.0 1.5 0.0007 19.9 0.2 4.1 3 1 1 4 4 4 2 HEAT repeats RTP1_C1 PF10363.9 KXH29722.1 - 8.3e-05 22.7 0.1 0.044 14.0 0.0 3.6 2 1 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 KXH29722.1 - 9.2e-05 22.9 5.9 0.13 12.8 0.3 4.9 4 0 0 4 4 4 1 HEAT-like repeat Adaptin_N PF01602.20 KXH29722.1 - 0.00046 18.9 5.8 0.014 14.0 0.2 3.3 3 1 0 3 3 3 2 Adaptin N terminal region Cnd3 PF12719.7 KXH29722.1 - 0.0026 17.0 0.8 0.0026 17.0 0.8 3.2 3 1 1 4 4 4 1 Nuclear condensing complex subunits, C-term domain DUF5445 PF17520.2 KXH29722.1 - 0.063 13.1 0.3 1.9 8.4 0.0 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF5445) Cullin_binding PF03556.15 KXH29829.1 - 9.3e-35 119.7 6.9 1.8e-34 118.8 6.9 1.4 1 0 0 1 1 1 1 Cullin binding UBA_4 PF14555.6 KXH29829.1 - 6.6e-10 38.7 0.0 1.5e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain Ribosomal_S6 PF01250.17 KXH29830.1 - 1.7e-23 82.7 0.0 2e-23 82.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S6 SQS_PSY PF00494.19 KXH29831.1 - 4e-59 200.3 0.5 4.7e-59 200.0 0.5 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase SNF2_N PF00176.23 KXH29832.1 - 2.8e-68 230.2 0.2 3.9e-68 229.7 0.2 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.11 KXH29832.1 - 2.9e-25 88.0 0.0 5.6e-25 87.1 0.0 1.5 1 0 0 1 1 1 1 HIRAN domain ResIII PF04851.15 KXH29832.1 - 1.2e-06 28.6 0.0 2.6e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UBA_4 PF14555.6 KXH29832.1 - 0.0016 18.2 0.1 0.0033 17.2 0.1 1.5 1 0 0 1 1 1 1 UBA-like domain Zip PF02535.22 KXH29834.1 - 0.0036 16.6 0.7 0.0046 16.2 0.7 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter NicO PF03824.16 KXH29834.1 - 6 6.1 8.8 7.6 5.8 8.8 1.2 1 0 0 1 1 1 0 High-affinity nickel-transport protein SKG6 PF08693.10 KXH29835.1 - 0.0021 17.4 0.8 0.0044 16.4 0.8 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Amnionless PF14828.6 KXH29835.1 - 0.0092 14.8 0.0 0.011 14.6 0.0 1.0 1 0 0 1 1 1 1 Amnionless SARAF PF06682.12 KXH29835.1 - 0.07 12.8 0.0 0.081 12.6 0.0 1.0 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis HemY_N PF07219.13 KXH29835.1 - 0.07 13.3 0.2 0.096 12.9 0.2 1.2 1 0 0 1 1 1 0 HemY protein N-terminus DUF4703 PF15775.5 KXH29835.1 - 0.1 12.4 0.9 0.14 11.9 0.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4703) Shisa PF13908.6 KXH29835.1 - 0.11 12.8 0.0 0.13 12.5 0.0 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF5305 PF17231.2 KXH29835.1 - 0.12 11.7 0.0 0.15 11.4 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Ctr PF04145.15 KXH29835.1 - 0.13 12.9 0.0 0.15 12.7 0.0 1.1 1 0 0 1 1 1 0 Ctr copper transporter family Cucumo_2B PF03263.13 KXH29835.1 - 0.84 10.1 4.3 1.3 9.5 4.3 1.2 1 0 0 1 1 1 0 Cucumovirus protein 2B zf-RING_2 PF13639.6 KXH29836.1 - 0.0022 18.3 4.2 0.0022 18.3 4.2 2.0 2 0 0 2 2 2 1 Ring finger domain TnpV PF14198.6 KXH29836.1 - 0.16 11.9 0.0 0.32 11.0 0.0 1.5 1 0 0 1 1 1 0 Transposon-encoded protein TnpV SnoaL_4 PF13577.6 KXH29837.1 - 3.6e-08 33.6 0.2 3.4e-07 30.4 0.2 2.1 1 1 0 1 1 1 1 SnoaL-like domain CMD PF02627.20 KXH29837.1 - 0.06 13.4 0.0 0.099 12.7 0.0 1.4 1 0 0 1 1 1 0 Carboxymuconolactone decarboxylase family Glyco_hydro_17 PF00332.18 KXH29838.1 - 1.9e-11 44.1 0.8 2.5e-11 43.7 0.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 Sugar_tr PF00083.24 KXH29839.1 - 1.2e-54 185.9 8.3 1.3e-54 185.8 8.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH29839.1 - 1.5e-05 24.1 23.5 1.6e-05 24.0 22.8 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily SH PF01445.17 KXH29839.1 - 0.18 11.8 0.1 0.18 11.8 0.1 2.4 2 0 0 2 2 2 0 Viral small hydrophobic protein Ferlin_C PF16165.5 KXH29839.1 - 0.31 11.0 1.4 0.67 9.9 1.4 1.5 1 0 0 1 1 1 0 Ferlin C-terminus Herpes_LMP1 PF05297.11 KXH29839.1 - 0.59 9.3 4.4 0.51 9.5 3.1 1.5 1 1 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Glyco_hydro_3_C PF01915.22 KXH29840.1 - 2.7e-59 200.5 0.0 5.6e-59 199.5 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KXH29840.1 - 9.7e-48 163.2 0.0 6.9e-47 160.4 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KXH29840.1 - 5.4e-16 58.5 0.5 1.6e-15 56.9 0.5 1.9 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 KXH29840.1 - 2.3e-10 40.4 0.0 4.2e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 PA14 domain Fungal_trans PF04082.18 KXH29841.1 - 2e-08 33.6 1.3 3.7e-08 32.7 1.3 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_28 PF00295.17 KXH29842.1 - 3.2e-102 341.9 24.3 4.1e-102 341.6 24.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 ADH_zinc_N PF00107.26 KXH29843.1 - 1.2e-31 109.3 0.1 2e-31 108.7 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXH29843.1 - 1.5e-19 71.4 0.0 2.8e-19 70.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXH29843.1 - 1.2e-10 41.3 0.0 2.9e-10 40.0 0.0 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.18 KXH29843.1 - 0.00036 20.8 0.0 0.00065 19.9 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain p450 PF00067.22 KXH29845.1 - 5.3e-31 107.9 0.0 2.7e-17 62.7 0.0 2.1 1 1 1 2 2 2 2 Cytochrome P450 GGACT PF06094.12 KXH29845.1 - 2.6e-14 53.9 0.0 5.2e-14 52.9 0.0 1.5 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like Asp PF00026.23 KXH29846.1 - 3.6e-57 194.2 0.0 4.5e-57 193.9 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KXH29846.1 - 7.6e-15 55.6 1.2 9.1e-14 52.1 1.2 2.2 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KXH29846.1 - 0.024 15.3 0.1 5.4 7.7 0.0 3.3 2 1 0 2 2 2 0 Aspartyl protease gag-asp_proteas PF13975.6 KXH29846.1 - 0.052 14.1 0.0 1.8 9.2 0.0 2.9 2 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease Serglycin PF04360.12 KXH29846.1 - 0.084 12.8 2.7 0.19 11.7 2.7 1.5 1 0 0 1 1 1 0 Serglycin HET PF06985.11 KXH29847.1 - 2.6e-23 83.0 0.0 6.8e-23 81.6 0.0 1.8 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) zf-H2C2_2 PF13465.6 KXH29847.1 - 2.6e-07 30.7 0.3 2.6e-07 30.7 0.3 5.3 5 0 0 5 5 4 2 Zinc-finger double domain zf-C2H2 PF00096.26 KXH29847.1 - 2.5e-05 24.5 26.1 5.3e-05 23.5 3.2 5.3 5 0 0 5 5 5 2 Zinc finger, C2H2 type NACHT PF05729.12 KXH29847.1 - 9.3e-05 22.4 0.0 0.00027 20.9 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KXH29847.1 - 0.01 16.2 0.1 0.041 14.3 0.0 2.0 2 0 0 2 2 1 0 AAA ATPase domain AAA_22 PF13401.6 KXH29847.1 - 0.036 14.3 0.1 0.34 11.2 0.0 2.7 3 0 0 3 3 3 0 AAA domain zf-C2H2_4 PF13894.6 KXH29847.1 - 0.041 14.7 21.9 0.031 15.1 2.5 5.4 4 0 0 4 4 3 0 C2H2-type zinc finger RNA_helicase PF00910.22 KXH29847.1 - 0.042 14.2 0.0 0.13 12.6 0.0 1.9 1 0 0 1 1 1 0 RNA helicase zf-C2H2_6 PF13912.6 KXH29847.1 - 0.073 13.1 10.0 0.3 11.1 1.8 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger zf-met PF12874.7 KXH29847.1 - 0.16 12.4 1.1 0.8 10.2 1.1 2.3 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 KXH29847.1 - 0.45 10.3 4.1 0.17 11.7 0.8 2.0 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 KXH29847.1 - 0.99 9.8 4.5 7 7.1 1.0 3.8 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding SNF2_N PF00176.23 KXH29848.1 - 7.1e-58 196.0 0.8 2.5e-57 194.2 0.8 1.8 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KXH29848.1 - 5e-15 55.8 0.0 1.2e-14 54.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXH29848.1 - 7.6e-07 29.3 0.1 1.5e-05 25.1 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-RING_5 PF14634.6 KXH29848.1 - 0.00018 21.4 6.0 0.00035 20.5 6.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain DEAD PF00270.29 KXH29848.1 - 0.00023 21.0 0.0 0.0027 17.5 0.0 2.6 3 0 0 3 3 3 1 DEAD/DEAH box helicase Prok-RING_4 PF14447.6 KXH29848.1 - 0.003 17.4 2.8 0.012 15.5 2.8 2.0 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KXH29848.1 - 0.032 14.6 6.1 0.1 13.0 6.1 2.0 1 0 0 1 1 1 0 Ring finger domain ERCC3_RAD25_C PF16203.5 KXH29848.1 - 0.11 11.7 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase zf-C3HC4 PF00097.25 KXH29848.1 - 0.15 11.9 6.4 0.41 10.6 6.4 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXH29848.1 - 0.18 11.7 10.8 0.22 11.4 5.6 3.6 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXH29848.1 - 0.27 11.3 5.7 0.71 9.9 5.7 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KXH29848.1 - 0.27 11.1 4.5 0.69 9.8 4.5 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.21 KXH29848.1 - 0.87 9.8 3.6 2.2 8.5 3.6 1.6 1 0 0 1 1 1 0 FYVE zinc finger Fungal_trans PF04082.18 KXH29850.1 - 1.6e-19 70.0 0.2 2.3e-19 69.5 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KXH29850.1 - 1.3e-08 34.8 13.4 0.00019 21.7 2.0 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KXH29850.1 - 1.3e-06 28.6 12.9 2.3e-06 27.8 7.1 2.7 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KXH29850.1 - 0.00049 20.7 13.0 0.037 14.9 2.1 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger C1_4 PF07975.12 KXH29850.1 - 0.38 11.0 2.1 0.91 9.8 2.1 1.6 1 0 0 1 1 1 0 TFIIH C1-like domain zf-C2H2_jaz PF12171.8 KXH29850.1 - 0.9 9.9 3.7 0.44 10.9 0.4 2.2 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KXH29850.1 - 2.7 8.5 5.2 0.64 10.5 1.1 2.1 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Zn_clus PF00172.18 KXH29852.1 - 1.2e-06 28.6 9.5 1.9e-06 27.9 9.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KXH29852.1 - 0.038 12.8 0.4 0.078 11.8 0.4 1.5 1 0 0 1 1 1 0 Fungal specific transcription factor domain Glyco_hydro_3_C PF01915.22 KXH29853.1 - 1.4e-46 159.0 0.0 2.2e-46 158.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KXH29853.1 - 8.1e-31 107.6 0.0 1.4e-30 106.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KXH29853.1 - 8.9e-24 83.4 0.1 1.8e-23 82.4 0.1 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain RTA1 PF04479.13 KXH29854.1 - 4.9e-71 238.6 10.2 7.9e-71 237.9 10.2 1.3 1 0 0 1 1 1 1 RTA1 like protein MTABC_N PF16185.5 KXH29854.1 - 0.064 12.8 3.4 0.12 11.8 3.4 1.4 1 0 0 1 1 1 0 Mitochondrial ABC-transporter N-terminal five TM region DUF373 PF04123.13 KXH29854.1 - 3.1 7.2 12.7 0.88 8.9 5.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF373) FAD_binding_4 PF01565.23 KXH29855.1 - 1.6e-23 83.0 2.3 3.9e-23 81.7 1.7 1.9 1 1 1 2 2 2 1 FAD binding domain BBE PF08031.12 KXH29855.1 - 5.1e-10 39.3 0.8 1.3e-09 38.0 0.8 1.7 1 0 0 1 1 1 1 Berberine and berberine like DUF1772 PF08592.11 KXH29856.1 - 1.8e-33 115.8 0.3 2.2e-33 115.5 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) DUF5366 PF17328.2 KXH29856.1 - 0.024 14.8 0.1 0.039 14.1 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5366) AA_permease PF00324.21 KXH29857.1 - 1.1e-130 436.4 51.9 1.4e-130 436.1 51.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KXH29857.1 - 1.6e-32 112.9 57.5 1.9e-32 112.7 57.5 1.1 1 0 0 1 1 1 1 Amino acid permease NCE101 PF11654.8 KXH29857.1 - 0.26 11.0 0.9 0.72 9.6 0.1 2.1 2 0 0 2 2 2 0 Non-classical export protein 1 Amidohydro_2 PF04909.14 KXH29858.1 - 4.8e-43 148.0 0.7 6.1e-43 147.7 0.7 1.1 1 0 0 1 1 1 1 Amidohydrolase DUF1932 PF09130.11 KXH29859.1 - 4.5e-23 81.0 0.2 1.1e-22 79.8 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1932) NAD_binding_2 PF03446.15 KXH29859.1 - 1.3e-05 25.5 0.0 2.1e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KXH29859.1 - 0.00016 22.2 0.1 0.00031 21.2 0.1 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent PDH PF02153.17 KXH29859.1 - 0.014 14.4 0.0 0.029 13.4 0.0 1.5 2 0 0 2 2 2 0 Prephenate dehydrogenase 3HCDH_N PF02737.18 KXH29859.1 - 0.022 14.6 0.0 0.043 13.7 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HET PF06985.11 KXH29860.1 - 4.1e-24 85.6 0.0 7e-24 84.8 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) FixH PF05751.11 KXH29861.1 - 0.71 9.9 0.0 0.71 9.9 0.0 3.3 3 0 0 3 3 3 0 FixH Methyltransf_23 PF13489.6 KXH29862.1 - 4.5e-20 72.1 0.0 7.6e-20 71.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH29862.1 - 1.1e-11 45.2 0.0 2.7e-11 44.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH29862.1 - 5.1e-10 40.0 0.0 5.4e-09 36.7 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH29862.1 - 2.4e-09 37.2 0.0 8.4e-09 35.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH29862.1 - 3.4e-08 34.0 0.0 7.8e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXH29862.1 - 0.00075 19.1 0.0 0.0023 17.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_4 PF02390.17 KXH29862.1 - 0.001 18.6 0.0 0.0028 17.2 0.0 1.7 1 0 0 1 1 1 1 Putative methyltransferase FtsJ PF01728.19 KXH29862.1 - 0.0061 16.7 0.0 0.0096 16.0 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase CMAS PF02353.20 KXH29862.1 - 0.0083 15.5 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_2 PF00891.18 KXH29862.1 - 0.019 14.3 0.1 1.3 8.3 0.0 2.2 2 0 0 2 2 2 0 O-methyltransferase domain PrmA PF06325.13 KXH29862.1 - 0.036 13.5 0.0 0.062 12.7 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.9 KXH29862.1 - 0.048 13.4 0.0 0.08 12.7 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase PCMT PF01135.19 KXH29862.1 - 0.25 11.1 0.0 1.1 9.0 0.0 1.8 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) p450 PF00067.22 KXH29863.1 - 5.1e-36 124.4 0.0 8e-36 123.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 HU-CCDC81_euk_2 PF18289.1 KXH29863.1 - 0.13 12.5 0.0 0.33 11.1 0.0 1.6 1 0 0 1 1 1 0 CCDC81 eukaryotic HU domain 2 Abhydrolase_1 PF00561.20 KXH29864.1 - 1e-22 81.0 0.0 8.7e-22 78.0 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXH29864.1 - 1.1e-14 54.3 0.0 1.3e-14 54.0 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KXH29864.1 - 4.4e-12 47.1 0.0 5.6e-12 46.7 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 KXH29864.1 - 0.00013 22.0 0.0 0.00036 20.6 0.0 1.6 2 0 0 2 2 2 1 TAP-like protein Esterase PF00756.20 KXH29864.1 - 0.0067 16.1 0.0 0.0084 15.8 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Peptidase_S28 PF05577.12 KXH29864.1 - 0.011 14.5 0.0 0.016 14.0 0.0 1.2 1 0 0 1 1 1 0 Serine carboxypeptidase S28 Ndr PF03096.14 KXH29864.1 - 0.022 13.5 0.0 0.038 12.7 0.0 1.4 1 0 0 1 1 1 0 Ndr family Acyl_transf_2 PF02273.15 KXH29864.1 - 0.03 13.5 0.0 0.057 12.6 0.0 1.4 1 0 0 1 1 1 0 Acyl transferase PGAP1 PF07819.13 KXH29864.1 - 0.063 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Esterase_phd PF10503.9 KXH29864.1 - 0.1 12.0 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Esterase PHB depolymerase NAD_binding_2 PF03446.15 KXH29865.1 - 6.1e-33 114.2 0.1 8.8e-33 113.7 0.1 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KXH29865.1 - 4.5e-20 72.1 0.0 6.4e-20 71.6 0.0 1.2 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase OCD_Mu_crystall PF02423.15 KXH29865.1 - 1.2e-05 24.4 0.1 2.6e-05 23.3 0.0 1.5 2 0 0 2 2 2 1 Ornithine cyclodeaminase/mu-crystallin family GFO_IDH_MocA PF01408.22 KXH29865.1 - 4.2e-05 24.3 0.1 8.1e-05 23.4 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Sacchrp_dh_NADP PF03435.18 KXH29865.1 - 0.0018 18.6 0.1 0.0041 17.4 0.0 1.6 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain F420_oxidored PF03807.17 KXH29865.1 - 0.0046 17.5 0.2 0.017 15.7 0.1 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent CoA_binding PF02629.19 KXH29865.1 - 0.0072 17.0 0.2 0.017 15.8 0.2 1.6 1 0 0 1 1 1 1 CoA binding domain NAD_binding_10 PF13460.6 KXH29866.1 - 2.1e-14 53.8 0.0 1.8e-10 41.0 0.0 2.1 2 0 0 2 2 2 2 NAD(P)H-binding Epimerase PF01370.21 KXH29866.1 - 0.00014 21.4 0.0 0.0003 20.3 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXH29866.1 - 0.0067 15.9 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 KXH29866.1 - 0.045 13.3 0.0 0.066 12.8 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family Hpr_kinase_C PF07475.12 KXH29866.1 - 0.17 11.4 0.3 0.34 10.4 0.3 1.4 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain adh_short PF00106.25 KXH29867.1 - 6.5e-30 104.1 0.5 3.9e-19 68.9 0.0 2.1 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXH29867.1 - 3.7e-22 79.0 0.1 2.8e-19 69.6 0.1 2.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH29867.1 - 6.3e-05 23.0 0.6 0.0093 15.9 0.0 2.3 1 1 1 2 2 2 2 KR domain Epimerase PF01370.21 KXH29867.1 - 0.00037 20.0 0.1 0.0016 18.0 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family AlaDh_PNT_C PF01262.21 KXH29867.1 - 0.0046 16.3 0.0 0.0069 15.7 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 KXH29867.1 - 0.09 12.1 0.1 0.14 11.5 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N PF00107.26 KXH29867.1 - 0.1 12.5 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Polysacc_synt_2 PF02719.15 KXH29867.1 - 0.18 10.9 0.0 0.27 10.3 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein CMD PF02627.20 KXH29868.1 - 2.1e-20 72.5 0.2 3.5e-20 71.8 0.2 1.4 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family DUF2827 PF10933.8 KXH29868.1 - 0.06 12.0 0.0 0.075 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2827) NAD_binding_2 PF03446.15 KXH29869.1 - 2.9e-36 125.0 0.0 6.9e-36 123.8 0.0 1.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KXH29869.1 - 3.4e-22 79.0 0.0 6.8e-22 78.0 0.0 1.6 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Fungal_trans PF04082.18 KXH29869.1 - 2.3e-10 40.0 0.2 4.1e-10 39.1 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KXH29869.1 - 1.5e-05 25.2 19.1 0.0026 18.1 3.3 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type Lactamase_B PF00753.27 KXH29869.1 - 0.00026 21.1 1.5 0.00065 19.8 1.5 1.7 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily OCD_Mu_crystall PF02423.15 KXH29869.1 - 0.0014 17.7 0.0 0.0023 16.9 0.0 1.2 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family F420_oxidored PF03807.17 KXH29869.1 - 0.0018 18.8 0.0 0.0048 17.4 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent zf-H2C2_2 PF13465.6 KXH29869.1 - 0.0024 18.2 18.0 0.045 14.2 10.5 2.9 2 0 0 2 2 2 2 Zinc-finger double domain Lactamase_B_2 PF12706.7 KXH29869.1 - 0.0052 16.3 0.1 0.015 14.8 0.1 1.7 1 0 0 1 1 1 1 Beta-lactamase superfamily domain zf-C2H2_4 PF13894.6 KXH29869.1 - 0.0094 16.7 17.0 0.3 12.0 2.5 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger DUF575 PF04746.12 KXH29869.1 - 0.17 12.2 0.0 1.2 9.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF575) zf-BED PF02892.15 KXH29869.1 - 2.1 8.4 10.4 2.6 8.2 3.6 2.7 1 1 1 2 2 2 0 BED zinc finger FAD_binding_4 PF01565.23 KXH29871.1 - 2e-19 69.7 0.1 3.1e-19 69.1 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain DLH PF01738.18 KXH29872.1 - 8.3e-24 84.3 0.0 1.1e-23 84.0 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 KXH29872.1 - 0.037 13.7 0.0 0.053 13.1 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold adh_short_C2 PF13561.6 KXH29873.1 - 6.8e-47 160.0 0.3 8e-47 159.8 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXH29873.1 - 6.9e-39 133.3 0.1 8.6e-39 133.0 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXH29873.1 - 9.8e-07 28.8 0.4 1.3e-06 28.4 0.4 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXH29873.1 - 0.015 14.8 0.1 0.061 12.8 0.1 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXH29873.1 - 0.04 13.3 0.0 0.051 13.0 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase 3HCDH_N PF02737.18 KXH29873.1 - 0.05 13.5 0.1 0.069 13.0 0.1 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MTS PF05175.14 KXH29873.1 - 0.13 11.8 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain EthD PF07110.11 KXH29874.1 - 3e-05 25.1 0.1 7e-05 23.9 0.1 1.6 1 1 0 1 1 1 1 EthD domain Glyco_hydro_43 PF04616.14 KXH29875.1 - 6.6e-58 196.3 8.4 8.9e-58 195.9 8.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 DUF1080 PF06439.11 KXH29875.1 - 3e-06 27.5 0.1 5.8e-06 26.5 0.1 1.4 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1080) Glyco_hydro_32N PF00251.20 KXH29875.1 - 5.5e-05 22.9 2.8 0.00011 21.9 2.8 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain AzlC PF03591.14 KXH29876.1 - 0.023 15.2 3.2 0.023 15.2 3.2 3.0 3 0 0 3 3 3 0 AzlC protein MmgE_PrpD PF03972.14 KXH29877.1 - 2.1e-110 369.3 0.3 2.4e-110 369.1 0.3 1.0 1 0 0 1 1 1 1 MmgE/PrpD family DUF2650 PF10853.8 KXH29878.1 - 7.5 6.4 9.5 0.48 10.2 3.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2650) F-box PF00646.33 KXH29879.1 - 0.027 14.4 5.6 0.36 10.8 0.0 3.2 4 0 0 4 4 4 0 F-box domain Glyco_hydro_10 PF00331.20 KXH29880.1 - 1.7e-101 339.5 0.1 2e-101 339.3 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_1 PF00734.18 KXH29880.1 - 1.5e-12 47.3 9.7 1.5e-12 47.3 9.7 2.1 2 0 0 2 2 2 1 Fungal cellulose binding domain YqjK PF13997.6 KXH29881.1 - 0.25 11.6 0.2 0.25 11.6 0.2 2.5 3 0 0 3 3 3 0 YqjK-like protein TFIIA PF03153.13 KXH29881.1 - 0.66 9.9 5.9 0.94 9.4 5.9 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SBP_bac_8 PF13416.6 KXH29882.1 - 3.5e-11 43.4 3.9 1.7e-10 41.2 3.9 1.8 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_6 PF13343.6 KXH29882.1 - 1.3e-10 41.1 1.2 2.2e-10 40.3 1.2 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.6 KXH29882.1 - 6e-05 22.9 0.0 0.0001 22.1 0.0 1.4 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 KXH29882.1 - 0.0006 19.9 7.0 0.0016 18.5 7.0 1.6 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein Aminotran_1_2 PF00155.21 KXH29883.1 - 3.4e-47 161.4 0.0 4.1e-47 161.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Arrestin_C PF02752.22 KXH29884.1 - 1.4e-14 54.6 0.0 1.1e-13 51.7 0.0 2.3 1 1 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 KXH29884.1 - 3.5e-07 30.4 0.0 0.0078 16.3 0.0 2.4 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Nha1_C PF08619.10 KXH29885.1 - 1.5e-130 436.5 30.9 1.9e-130 436.2 30.9 1.0 1 0 0 1 1 1 1 Alkali metal cation/H+ antiporter Nha1 C terminus Na_H_Exchanger PF00999.21 KXH29885.1 - 1.2e-75 254.7 23.7 1.5e-75 254.4 23.7 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.6 KXH29885.1 - 7.1 6.8 8.9 0.45 10.6 0.2 3.0 3 0 0 3 3 3 0 YrhC-like protein DUF3433 PF11915.8 KXH29888.1 - 9.3e-26 90.1 12.1 6.2e-17 61.8 0.2 2.9 2 0 0 2 2 2 2 Protein of unknown function (DUF3433) DUF4064 PF13273.6 KXH29888.1 - 1.3 9.3 5.0 2 8.7 1.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF4064) COX2_TM PF02790.15 KXH29888.1 - 4 7.6 6.8 1.9 8.7 0.6 3.1 3 0 0 3 3 3 0 Cytochrome C oxidase subunit II, transmembrane domain DUF3433 PF11915.8 KXH29890.1 - 4.3e-33 113.6 20.3 2.7e-20 72.6 0.7 3.4 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) Zn_clus PF00172.18 KXH29891.1 - 6.9e-08 32.5 7.6 1.3e-07 31.6 7.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NOZZLE PF08744.10 KXH29891.1 - 0.17 11.4 0.0 0.28 10.6 0.0 1.2 1 0 0 1 1 1 0 Plant transcription factor NOZZLE GTP_EFTU PF00009.27 KXH29892.1 - 4.7e-19 68.7 0.0 8.3e-19 67.9 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 KXH29892.1 - 6.9e-09 36.0 0.4 4.6e-08 33.3 0.3 2.4 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.17 KXH29892.1 - 0.00011 22.5 0.0 0.00031 21.0 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 KXH29892.1 - 0.00021 21.4 0.3 0.00076 19.5 0.2 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KXH29892.1 - 0.0005 20.0 0.7 0.64 9.9 0.2 2.5 2 0 0 2 2 2 2 RsgA GTPase PduV-EutP PF10662.9 KXH29892.1 - 0.0056 16.4 0.4 0.71 9.6 0.1 3.2 2 1 1 3 3 3 1 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.23 KXH29892.1 - 0.046 13.8 0.1 0.16 12.0 0.1 1.9 1 0 0 1 1 1 0 Dynamin family Roc PF08477.13 KXH29892.1 - 0.14 12.4 0.1 1.1 9.5 0.0 2.3 1 1 1 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase LSM PF01423.22 KXH29893.1 - 2.9e-14 52.5 1.1 9.5e-14 50.9 0.7 2.0 2 1 0 2 2 2 1 LSM domain ATP13 PF12921.7 KXH29894.1 - 7.5e-17 61.2 0.0 1.7e-16 60.1 0.0 1.6 1 0 0 1 1 1 1 Mitochondrial ATPase expression PIG-L PF02585.17 KXH29895.1 - 5.9e-26 91.6 0.0 9e-26 91.1 0.0 1.3 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase Cwf_Cwc_15 PF04889.12 KXH29896.1 - 0.14 11.8 2.4 0.18 11.5 2.4 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein ATP-synt_8 PF00895.20 KXH29896.1 - 1.1 9.8 3.6 2.5 8.6 1.0 2.3 1 1 1 2 2 2 0 ATP synthase protein 8 Flu_M2 PF00599.17 KXH29897.1 - 0.027 14.6 0.0 0.05 13.7 0.0 1.4 1 0 0 1 1 1 0 Influenza Matrix protein (M2) Ssu72 PF04722.13 KXH29898.1 - 0.056 13.0 0.1 0.1 12.1 0.1 1.4 1 0 0 1 1 1 0 Ssu72-like protein GAS PF13851.6 KXH29898.1 - 0.058 12.8 9.5 0.27 10.6 9.6 1.7 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding PRKG1_interact PF15898.5 KXH29898.1 - 0.19 12.7 5.2 3.7 8.5 0.0 2.4 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain CASP_C PF08172.12 KXH29898.1 - 0.2 11.0 9.2 1.7 8.0 0.6 2.2 2 0 0 2 2 2 0 CASP C terminal FUSC PF04632.12 KXH29898.1 - 0.41 9.1 5.8 0.16 10.5 2.5 1.7 1 1 1 2 2 2 0 Fusaric acid resistance protein family TolA_bind_tri PF16331.5 KXH29898.1 - 0.47 10.6 12.9 0.74 9.9 1.3 2.4 2 0 0 2 2 2 0 TolA binding protein trimerisation YabA PF06156.13 KXH29898.1 - 0.86 10.3 12.1 8.3 7.1 2.4 2.5 1 1 1 2 2 2 0 Initiation control protein YabA DivIC PF04977.15 KXH29898.1 - 1.1 9.1 10.2 0.37 10.6 0.3 2.9 2 1 1 3 3 3 0 Septum formation initiator NUDIX PF00293.28 KXH29900.1 - 9.5e-16 58.0 0.6 1.3e-15 57.6 0.6 1.2 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 KXH29900.1 - 0.11 12.6 0.0 0.23 11.5 0.0 1.6 1 1 0 1 1 1 0 NUDIX domain PRIMA1 PF16101.5 KXH29900.1 - 2.4 8.2 6.1 3.3 7.7 6.1 1.3 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Linker_histone PF00538.19 KXH29903.1 - 7.9e-28 96.6 0.1 7.9e-28 96.6 0.1 2.1 2 1 0 2 2 2 1 linker histone H1 and H5 family Asp-B-Hydro_N PF05279.11 KXH29903.1 - 3.9 7.5 31.1 5 7.1 31.1 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region 4HBT_2 PF13279.6 KXH29904.1 - 1e-22 80.9 0.1 1.5e-22 80.4 0.1 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 KXH29904.1 - 0.0032 17.8 0.1 0.0071 16.7 0.0 1.6 2 0 0 2 2 2 1 Thioesterase superfamily HRI1 PF16815.5 KXH29905.1 - 4.9e-80 268.5 6.8 5.5e-80 268.4 6.8 1.0 1 0 0 1 1 1 1 Protein HRI1 FA_hydroxylase PF04116.13 KXH29908.1 - 7.6e-10 39.3 10.2 3.4e-09 37.1 10.2 2.0 1 1 0 1 1 1 1 Fatty acid hydroxylase superfamily Glyco_transf_90 PF05686.12 KXH29909.1 - 4.7e-12 45.5 2.4 4.2e-10 39.1 2.1 2.9 2 1 0 2 2 2 2 Glycosyl transferase family 90 Abhydrolase_3 PF07859.13 KXH29936.1 - 8.5e-15 55.2 0.0 1e-14 54.9 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold HATPase_c PF02518.26 KXH29937.1 - 1.9e-21 76.7 0.0 4.5e-21 75.4 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KXH29937.1 - 3.9e-18 65.7 0.0 8e-18 64.6 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 KXH29937.1 - 1.1e-12 47.8 0.0 3.3e-12 46.2 0.0 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF PF01590.26 KXH29937.1 - 4.4e-08 33.8 0.0 3.6e-07 30.9 0.0 2.7 4 0 0 4 4 4 1 GAF domain Trp_oprn_chp PF09534.10 KXH29943.1 - 4.7 7.0 15.0 6.7 6.5 0.2 4.1 4 0 0 4 4 4 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) MMR_HSR1_C PF08438.10 KXH29944.1 - 1.7e-37 128.4 0.0 3e-37 127.6 0.0 1.4 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.23 KXH29944.1 - 4e-21 75.2 0.0 1.2e-20 73.7 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KXH29944.1 - 3.7e-09 36.3 0.2 1.8e-07 30.8 0.0 2.6 3 0 0 3 3 3 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KXH29944.1 - 0.00098 19.1 0.3 0.13 12.1 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 KXH29944.1 - 0.0019 17.8 0.1 0.92 9.0 0.0 3.0 3 0 0 3 3 3 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 KXH29944.1 - 0.0089 16.1 0.6 0.16 12.0 0.2 2.7 3 0 0 3 3 3 1 Dynamin family ABC_tran PF00005.27 KXH29944.1 - 0.093 13.3 0.0 0.49 10.9 0.0 2.1 2 0 0 2 2 2 0 ABC transporter Ploopntkinase3 PF18751.1 KXH29944.1 - 0.099 12.5 0.0 0.27 11.1 0.0 1.7 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 MMR_HSR1_Xtn PF16897.5 KXH29944.1 - 0.17 11.9 0.2 0.34 10.9 0.2 1.4 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain AIG1 PF04548.16 KXH29944.1 - 0.19 11.0 0.1 0.93 8.8 0.0 2.0 2 0 0 2 2 2 0 AIG1 family Pmp3 PF01679.17 KXH29945.1 - 1.3e-24 86.2 7.5 1.4e-24 86.0 7.5 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator PIG-F PF06699.11 KXH29946.1 - 4.4e-64 216.0 4.1 5.3e-64 215.7 4.1 1.1 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F PsbI PF02532.14 KXH29946.1 - 0.043 13.8 0.1 0.043 13.8 0.1 2.6 3 1 1 4 4 4 0 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) Actin PF00022.19 KXH29947.1 - 1.6e-127 425.5 0.0 5.8e-127 423.7 0.0 1.7 1 1 0 1 1 1 1 Actin DUF3602 PF12223.8 KXH29948.1 - 0.00044 20.8 0.2 0.0015 19.1 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3602) HET PF06985.11 KXH29949.1 - 2.3e-26 92.9 0.0 4.3e-26 92.0 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Aconitase PF00330.20 KXH29950.1 - 7e-148 493.4 0.0 9.3e-148 493.0 0.0 1.2 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KXH29950.1 - 5.7e-38 130.2 0.0 9.5e-38 129.5 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF521 PF04412.13 KXH29950.1 - 0.014 14.1 0.0 0.022 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF521) COPIIcoated_ERV PF07970.12 KXH29951.1 - 7.3e-37 127.4 0.1 1.4e-36 126.5 0.1 1.4 1 1 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 KXH29951.1 - 2.3e-25 88.8 0.0 4.1e-25 87.9 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) N_BRCA1_IG PF16158.5 KXH29952.1 - 6e-35 120.0 0.0 2.5e-34 118.1 0.0 2.1 2 0 0 2 2 2 1 Ig-like domain from next to BRCA1 gene ZZ PF00569.17 KXH29952.1 - 9.1e-18 63.8 62.7 4.2e-06 26.5 8.4 4.4 4 0 0 4 4 4 4 Zinc finger, ZZ type C1_2 PF03107.16 KXH29952.1 - 0.0041 17.4 51.8 0.11 12.8 10.6 4.5 4 0 0 4 4 4 3 C1 domain Exo_endo_phos PF03372.23 KXH29955.1 - 2.2e-07 30.6 0.0 3.5e-07 30.0 0.0 1.3 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 KXH29955.1 - 0.078 12.8 0.0 0.3 11.0 0.0 2.0 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase PLRV_ORF5 PF01690.17 KXH29958.1 - 0.036 12.8 9.9 0.082 11.6 0.6 2.8 1 1 1 3 3 3 0 Potato leaf roll virus readthrough protein N2227 PF07942.12 KXH29959.1 - 8.6e-96 320.3 0.0 2.2e-95 319.0 0.0 1.6 1 1 0 1 1 1 1 N2227-like protein Methyltransf_12 PF08242.12 KXH29959.1 - 0.0062 17.3 0.9 0.094 13.5 0.0 2.8 2 1 1 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXH29959.1 - 0.0066 16.3 0.0 0.015 15.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH29959.1 - 0.021 15.5 0.1 0.12 13.0 0.0 2.3 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.6 KXH29959.1 - 0.14 11.9 0.0 0.53 10.1 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain adh_short_C2 PF13561.6 KXH29960.1 - 9.1e-47 159.6 0.4 1.2e-46 159.1 0.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXH29960.1 - 8e-42 142.9 0.2 8e-42 142.9 0.2 1.3 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KXH29960.1 - 5.6e-12 45.9 0.1 1e-11 45.1 0.1 1.5 1 1 0 1 1 1 1 KR domain PemK_toxin PF02452.17 KXH29961.1 - 0.0067 16.8 0.0 0.016 15.6 0.0 1.5 1 1 0 1 1 1 1 PemK-like, MazF-like toxin of type II toxin-antitoxin system DUF5082 PF16888.5 KXH29962.1 - 0.065 13.5 2.1 0.67 10.2 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF5082) Atg14 PF10186.9 KXH29962.1 - 0.42 9.7 1.7 0.87 8.6 1.7 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 CAP_N PF01213.19 KXH29962.1 - 6.1 6.2 6.1 18 4.7 5.8 1.9 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Pap_E4 PF02711.14 KXH29962.1 - 7.4 7.6 7.4 26 5.9 1.3 3.5 2 1 1 3 3 3 0 E4 protein Cyclin_N PF00134.23 KXH29964.1 - 1.7e-13 50.5 0.0 3e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 KXH29964.1 - 1.7e-07 31.8 0.1 5.4e-07 30.1 0.1 1.9 1 1 0 1 1 1 1 Cyclin MAP65_ASE1 PF03999.12 KXH29964.1 - 2.4 6.8 8.7 0.13 11.0 3.5 1.4 2 0 0 2 2 2 0 Microtubule associated protein (MAP65/ASE1 family) CAF-1_p60_C PF15512.6 KXH29965.1 - 2.2 8.8 8.8 0.089 13.3 1.7 2.0 2 0 0 2 2 2 0 Chromatin assembly factor complex 1 subunit p60, C-terminal SET PF00856.28 KXH29966.1 - 2.2e-11 44.4 0.1 1.5e-10 41.7 0.0 2.3 2 1 0 2 2 2 1 SET domain HET PF06985.11 KXH29967.1 - 8.8e-29 100.7 0.1 2.9e-28 99.1 0.1 2.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Sugar_tr PF00083.24 KXH29968.1 - 1.1e-98 331.1 30.5 1.4e-98 330.7 30.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH29968.1 - 5.7e-22 78.1 32.9 5.7e-22 78.1 32.9 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily AA_permease PF00324.21 KXH29969.1 - 3.8e-102 342.4 43.5 4.6e-102 342.1 43.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KXH29969.1 - 1.6e-27 96.4 44.7 1.9e-27 96.2 44.7 1.1 1 0 0 1 1 1 1 Amino acid permease PNP_UDP_1 PF01048.20 KXH29970.1 - 6.1e-11 42.0 0.5 2e-10 40.3 0.5 1.7 1 1 0 1 1 1 1 Phosphorylase superfamily zf-H2C2_2 PF13465.6 KXH30179.1 - 0.042 14.3 0.2 0.042 14.3 0.2 4.2 5 0 0 5 5 5 0 Zinc-finger double domain zf-C2H2 PF00096.26 KXH30179.1 - 0.095 13.2 0.7 0.095 13.2 0.7 4.7 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXH30179.1 - 0.15 13.0 0.5 0.15 13.0 0.5 5.3 4 0 0 4 4 4 0 C2H2-type zinc finger Zn_clus PF00172.18 KXH30182.1 - 3.6e-09 36.6 7.7 5.6e-09 36.0 7.7 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CCAP PF11105.8 KXH30182.1 - 0.026 14.5 1.8 0.14 12.1 1.8 2.1 1 1 0 1 1 1 0 Arthropod cardioacceleratory peptide 2a DUF4778 PF16008.5 KXH30182.1 - 0.061 13.4 0.0 0.081 13.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) Clusterin PF01093.17 KXH30182.1 - 0.16 11.0 0.4 0.22 10.5 0.4 1.2 1 0 0 1 1 1 0 Clusterin bZIP_2 PF07716.15 KXH30183.1 - 4.6e-08 33.0 5.1 6.3e-08 32.6 5.1 1.2 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 KXH30183.1 - 0.00048 20.2 4.8 0.00071 19.6 4.8 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 KXH30183.1 - 0.00084 19.8 3.9 0.0013 19.2 3.9 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor Wbp11 PF09429.10 KXH30184.1 - 5.7e-17 61.9 12.8 5.7e-17 61.9 12.8 3.3 2 2 0 2 2 2 1 WW domain binding protein 11 Pkinase PF00069.25 KXH30185.1 - 2.7e-60 204.0 0.0 3.5e-59 200.3 0.0 2.3 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXH30185.1 - 1.2e-28 100.2 0.6 1.2e-19 70.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.24 KXH30185.1 - 0.0011 19.6 1.5 0.0011 19.6 1.5 2.3 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.6 KXH30185.1 - 0.0065 15.8 0.1 0.025 13.9 0.0 1.9 3 0 0 3 3 3 1 Kinase-like APH PF01636.23 KXH30185.1 - 0.0068 16.4 0.1 0.12 12.3 0.1 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KXH30185.1 - 0.035 13.1 0.0 0.069 12.1 0.0 1.4 1 1 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 KXH30185.1 - 0.036 13.4 0.0 0.068 12.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Trypan_PARP PF05887.11 KXH30186.1 - 5.9 6.9 7.7 9.4 6.2 7.7 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) WW PF00397.26 KXH30187.1 - 2.5e-10 40.2 0.1 6.5e-10 38.9 0.1 1.8 1 0 0 1 1 1 1 WW domain PhoD PF09423.10 KXH30187.1 - 0.00073 18.7 0.6 0.0079 15.3 0.6 2.1 1 1 0 1 1 1 1 PhoD-like phosphatase PMM PF03332.13 KXH30188.1 - 4.7e-103 343.7 0.2 5.4e-103 343.5 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 KXH30188.1 - 0.00048 20.0 0.0 0.002 17.9 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase MmgE_PrpD PF03972.14 KXH30189.1 - 0.24 9.9 4.3 0.32 9.5 4.3 1.1 1 0 0 1 1 1 0 MmgE/PrpD family Na_Ca_ex PF01699.24 KXH30190.1 - 3.9e-52 176.2 41.4 1.2e-27 96.7 18.6 2.7 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF5592 PF17332.2 KXH30190.1 - 0.017 15.7 0.2 0.017 15.7 0.2 3.0 3 0 0 3 3 3 0 Family of unknown function (DUF5592) Cnd2 PF05786.14 KXH30191.1 - 0 1048.2 7.8 0 1048.0 7.8 1.0 1 0 0 1 1 1 1 Condensin complex subunit 2 CNDH2_N PF06278.11 KXH30191.1 - 0.031 14.5 0.0 0.031 14.5 0.0 2.5 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal TraH_2 PF06871.11 KXH30191.1 - 0.25 10.9 4.2 0.58 9.8 4.2 1.6 1 0 0 1 1 1 0 TraH_2 BSP_II PF05432.11 KXH30191.1 - 0.49 10.0 13.9 3.1 7.4 5.0 2.4 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) His_Phos_1 PF00300.22 KXH30215.1 - 1e-19 71.0 0.0 3.8e-09 36.5 0.0 2.1 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) RabGAP-TBC PF00566.18 KXH30217.1 - 2.3e-26 92.8 0.2 5.7e-26 91.5 0.2 1.7 1 1 0 1 1 1 1 Rab-GTPase-TBC domain MFS_1 PF07690.16 KXH30219.1 - 7.5e-31 107.3 72.1 1.5e-22 80.0 40.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH30219.1 - 9.3e-13 47.8 23.8 9.9e-08 31.3 11.1 2.8 2 1 1 3 3 3 2 Sugar (and other) transporter MFS_2 PF13347.6 KXH30219.1 - 0.004 15.8 16.1 0.0081 14.8 15.7 1.8 1 1 0 1 1 1 1 MFS/sugar transport protein DUF1996 PF09362.10 KXH30220.1 - 6.2e-34 118.0 0.4 2.5e-32 112.8 0.4 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF1996) Lipase_GDSL_2 PF13472.6 KXH30221.1 - 4.5e-11 43.5 0.5 6e-11 43.1 0.5 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KXH30221.1 - 0.0048 16.9 0.3 0.0098 15.9 0.3 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase PSII_BNR PF14870.6 KXH30222.1 - 1.1e-11 44.6 7.4 4.8e-05 22.8 0.1 3.4 1 1 1 3 3 3 3 Photosynthesis system II assembly factor YCF48 Sortilin-Vps10 PF15902.5 KXH30222.1 - 5.8e-07 28.7 0.2 1.8e-05 23.7 0.0 2.4 2 1 0 2 2 2 1 Sortilin, neurotensin receptor 3, BNR PF02012.20 KXH30222.1 - 2.5e-06 26.7 22.1 0.46 10.7 0.5 6.3 5 1 0 5 5 5 4 BNR/Asp-box repeat BNR_2 PF13088.6 KXH30222.1 - 0.044 13.1 1.4 3.9 6.7 0.1 3.0 2 1 0 2 2 2 0 BNR repeat-like domain Mo-co_dimer PF03404.16 KXH30222.1 - 1.1 9.3 5.3 84 3.2 0.0 4.5 5 0 0 5 5 5 0 Mo-co oxidoreductase dimerisation domain p450 PF00067.22 KXH30223.1 - 5.5e-25 88.0 0.0 7.1e-25 87.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Arrestin_N PF00339.29 KXH30224.1 - 1.8e-06 28.1 0.3 5.6e-06 26.5 0.3 1.9 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 KXH30224.1 - 0.0011 19.5 0.6 2.7 8.4 0.0 2.8 2 1 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Bul1_C PF04426.12 KXH30224.1 - 0.0088 15.5 0.1 0.021 14.3 0.1 1.6 1 0 0 1 1 1 1 Bul1 C terminus ECH_1 PF00378.20 KXH30225.1 - 3.5e-40 137.9 0.2 1.4e-39 136.0 0.2 1.7 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXH30225.1 - 1.7e-18 67.2 0.1 3.1e-18 66.4 0.1 1.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 KXH30225.1 - 0.14 12.1 0.1 2.7 7.9 0.0 2.1 2 0 0 2 2 2 0 Peptidase family S49 NAD_binding_2 PF03446.15 KXH30226.1 - 5.2e-22 78.7 0.1 1.2e-21 77.5 0.0 1.6 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KXH30226.1 - 2e-15 57.1 0.4 3.3e-15 56.4 0.4 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Retinin_C PF04527.12 KXH30226.1 - 0.014 15.7 1.8 0.077 13.3 0.1 2.6 3 0 0 3 3 3 0 Drosophila Retinin like protein Homeobox_KN PF05920.11 KXH30227.1 - 1.1e-14 54.1 2.5 2.5e-14 52.9 2.5 1.7 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 KXH30227.1 - 7.7e-06 25.7 0.6 2.3e-05 24.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain zf-C2H2_4 PF13894.6 KXH30227.1 - 0.0025 18.5 4.1 0.0025 18.5 4.1 4.8 4 0 0 4 4 4 1 C2H2-type zinc finger zf-C2H2 PF00096.26 KXH30227.1 - 0.0038 17.6 23.9 0.0063 16.9 4.3 4.6 4 0 0 4 4 4 2 Zinc finger, C2H2 type Homez PF11569.8 KXH30227.1 - 0.14 11.6 0.0 0.33 10.4 0.0 1.6 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez zf-C2H2_2 PF12756.7 KXH30227.1 - 1.3 9.4 10.2 14 6.1 0.2 3.6 2 1 0 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 KXH30227.1 - 6.5 7.2 9.3 0.97 9.8 3.3 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding MFS_1 PF07690.16 KXH30228.1 - 1.3e-38 132.9 38.5 1.3e-38 132.9 38.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 KXH30230.1 - 9.8e-36 123.4 30.0 1.4e-35 122.9 30.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily GFA PF04828.14 KXH30231.1 - 3.5e-12 46.5 3.0 9.8e-07 29.0 0.6 3.3 2 1 0 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme NOB1_Zn_bind PF08772.11 KXH30231.1 - 0.7 10.1 7.6 0.82 9.9 0.1 2.9 3 0 0 3 3 3 0 Nin one binding (NOB1) Zn-ribbon like peroxidase PF00141.23 KXH30232.1 - 4.2e-82 275.3 0.2 9.3e-45 153.1 0.0 2.2 2 0 0 2 2 2 2 Peroxidase MFS_1 PF07690.16 KXH30233.1 - 1.2e-46 159.2 54.3 1.2e-46 159.2 54.3 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KXH30233.1 - 2.1e-15 56.2 24.5 1.4e-14 53.5 24.5 2.1 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KXH30233.1 - 1.2e-11 44.2 8.5 1.2e-11 44.2 8.5 3.2 2 1 1 3 3 3 1 Sugar (and other) transporter adh_short PF00106.25 KXH30234.1 - 4.2e-25 88.4 0.2 2.2e-21 76.2 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXH30234.1 - 7.8e-15 55.1 0.0 2.5e-13 50.1 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH30234.1 - 1.3e-11 44.7 0.0 1.9e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXH30234.1 - 2.4e-07 30.5 0.0 3.2e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 KXH30234.1 - 0.00062 20.0 0.0 0.0011 19.3 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 KXH30234.1 - 0.0042 17.1 0.0 0.0079 16.3 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.15 KXH30234.1 - 0.0057 15.8 0.0 0.0076 15.4 0.0 1.3 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein SPO22 PF08631.10 KXH30234.1 - 0.016 14.7 0.0 0.022 14.3 0.0 1.2 1 0 0 1 1 1 0 Meiosis protein SPO22/ZIP4 like Semialdhyde_dh PF01118.24 KXH30234.1 - 0.029 14.8 0.0 0.072 13.5 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DUF3425 PF11905.8 KXH30235.1 - 2.4e-24 85.7 0.0 4e-24 84.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) Acetyltransf_1 PF00583.25 KXH30236.1 - 1e-16 61.2 0.1 1.3e-16 60.9 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXH30236.1 - 5.8e-11 42.7 0.0 8.8e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KXH30236.1 - 1.7e-09 37.7 0.0 2.3e-09 37.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KXH30236.1 - 4.5e-07 30.6 0.0 6.1e-07 30.2 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KXH30236.1 - 2.7e-05 24.3 0.0 3e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXH30236.1 - 0.017 15.0 0.1 0.052 13.5 0.1 1.9 1 1 1 2 2 2 0 FR47-like protein Acetyltransf_CG PF14542.6 KXH30236.1 - 0.04 14.0 0.0 0.074 13.2 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_8 PF13523.6 KXH30236.1 - 0.14 11.8 0.0 0.61 9.8 0.0 1.8 1 1 0 2 2 2 0 Acetyltransferase (GNAT) domain DUF4231 PF14015.6 KXH30237.1 - 0.23 11.9 2.6 0.2 12.2 0.9 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) Ank_4 PF13637.6 KXH30239.1 - 5.1e-06 26.9 0.1 0.00048 20.7 0.0 2.7 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXH30239.1 - 0.00022 21.7 0.0 0.0047 17.5 0.0 2.2 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) F-box PF00646.33 KXH30239.1 - 0.00054 19.8 0.3 0.0012 18.7 0.3 1.5 1 0 0 1 1 1 1 F-box domain Ank_5 PF13857.6 KXH30239.1 - 0.0017 18.6 0.1 0.0041 17.4 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXH30239.1 - 0.028 14.9 0.7 1.6 9.6 0.1 3.5 3 1 1 4 4 4 0 Ankyrin repeat Glyco_transf_15 PF01793.16 KXH30240.1 - 9.9e-59 199.2 1.2 9.5e-39 133.5 0.4 3.0 2 1 0 2 2 2 2 Glycolipid 2-alpha-mannosyltransferase SnoaL_2 PF12680.7 KXH30241.1 - 0.024 15.3 0.1 0.085 13.5 0.0 1.9 2 0 0 2 2 2 0 SnoaL-like domain Peptidase_M76 PF09768.9 KXH30241.1 - 0.068 12.9 0.1 0.14 11.9 0.1 1.4 1 0 0 1 1 1 0 Peptidase M76 family DUF1348 PF07080.11 KXH30241.1 - 0.12 12.3 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1348) SnoaL_2 PF12680.7 KXH30242.1 - 0.0012 19.4 0.0 0.002 18.8 0.0 1.5 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 KXH30242.1 - 0.004 17.5 0.0 0.0058 17.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) Acetyltransf_1 PF00583.25 KXH30243.1 - 3.8e-10 40.0 0.0 4.7e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXH30243.1 - 2.3e-07 30.8 0.0 3.3e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXH30243.1 - 3.4e-06 27.4 0.0 4.9e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXH30243.1 - 0.0063 16.5 0.0 0.0099 15.8 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein FtsJ PF01728.19 KXH30244.1 - 2.4e-62 210.2 0.0 3.3e-62 209.7 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase DEAD PF00270.29 KXH30245.1 - 1.4e-45 155.2 0.0 3.8e-44 150.6 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXH30245.1 - 4.6e-26 91.3 0.1 1.3e-25 89.9 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CCDC117 PF15810.5 KXH30245.1 - 5.7 7.2 13.1 0.55 10.5 0.3 3.2 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 117 CRCB PF02537.15 KXH30247.1 - 2.1 8.7 8.1 0.33 11.3 4.2 1.8 2 0 0 2 2 2 0 CrcB-like protein, Camphor Resistance (CrcB) COesterase PF00135.28 KXH30248.1 - 1.1e-86 291.8 0.0 1.6e-86 291.2 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXH30248.1 - 0.0075 16.1 0.3 0.24 11.2 0.0 2.4 3 0 0 3 3 3 1 alpha/beta hydrolase fold Syndecan PF01034.20 KXH30250.1 - 9.7e-07 28.6 0.0 2.1e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Syndecan domain Glycophorin_A PF01102.18 KXH30250.1 - 0.041 14.1 0.0 0.13 12.5 0.0 1.8 1 0 0 1 1 1 0 Glycophorin A DUF4342 PF14242.6 KXH30250.1 - 0.2 11.7 0.9 0.37 10.8 0.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4342) Phage_holin_2_4 PF16082.5 KXH30250.1 - 0.47 10.2 3.3 1.2 9.0 3.3 1.7 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like TPR_MLP1_2 PF07926.12 KXH30251.1 - 4.7e-40 136.6 50.1 1.6e-39 134.9 31.1 19.7 7 5 11 21 21 21 7 TPR/MLP1/MLP2-like protein ZapB PF06005.12 KXH30251.1 - 0.0035 17.7 6.3 0.0035 17.7 6.3 25.9 13 8 1 16 16 16 1 Cell division protein ZapB Syntaxin_2 PF14523.6 KXH30251.1 - 0.0055 17.1 1.8 0.0055 17.1 1.8 15.7 9 5 4 14 14 14 1 Syntaxin-like protein IFT20 PF14931.6 KXH30251.1 - 0.0079 16.4 13.9 0.0079 16.4 13.9 17.1 9 5 7 18 18 18 2 Intraflagellar transport complex B, subunit 20 FlaC_arch PF05377.11 KXH30251.1 - 0.017 15.5 0.9 0.017 15.5 0.9 21.9 19 4 3 23 23 23 0 Flagella accessory protein C (FlaC) DUF3693 PF12472.8 KXH30251.1 - 0.073 12.7 0.5 0.37 10.5 0.5 2.2 1 0 0 1 1 1 0 Phage related protein HTH_Tnp_ISL3 PF13542.6 KXH30251.1 - 0.23 10.9 0.8 7.8 6.0 0.2 2.8 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 Surfac_D-trimer PF09006.11 KXH30251.1 - 6.4 6.8 15.4 63 3.6 0.0 6.4 5 0 0 5 5 5 0 Lung surfactant protein D coiled-coil trimerisation p450 PF00067.22 KXH30252.1 - 2.9e-43 148.3 0.0 4e-43 147.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.25 KXH30253.1 - 1.5e-30 106.1 0.0 2.3e-30 105.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXH30253.1 - 1.9e-22 80.0 0.0 5.3e-22 78.5 0.0 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH30253.1 - 0.021 14.7 0.0 0.038 13.9 0.0 1.3 1 0 0 1 1 1 0 KR domain FAD_binding_4 PF01565.23 KXH30255.1 - 9e-23 80.6 2.3 1.7e-22 79.7 1.8 1.7 2 0 0 2 2 2 1 FAD binding domain MFS_1 PF07690.16 KXH30256.1 - 2.4e-36 125.4 16.2 2.4e-36 125.4 16.2 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KXH30256.1 - 1.1e-05 24.9 4.5 1.1e-05 24.9 4.5 2.2 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB Cu-oxidase_2 PF07731.14 KXH30257.1 - 1.8e-38 131.3 5.5 1.8e-38 131.3 5.5 2.5 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 KXH30257.1 - 1.5e-37 128.3 2.3 1.5e-37 128.3 2.3 3.0 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase PF00394.22 KXH30257.1 - 2.3e-35 122.1 0.3 3.7e-34 118.1 0.1 2.4 2 0 0 2 2 2 1 Multicopper oxidase Cation_ATPase_C PF00689.21 KXH30259.1 - 1.1e-45 155.6 5.9 1.1e-45 155.6 5.9 2.0 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 KXH30259.1 - 7.8e-22 77.2 0.0 1.4e-21 76.4 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KXH30259.1 - 1.7e-21 77.5 0.3 4.7e-21 76.1 0.3 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KXH30259.1 - 2.7e-20 72.6 0.2 2.7e-20 72.6 0.2 2.5 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_N PF00690.26 KXH30259.1 - 9.3e-11 41.3 0.0 2.4e-09 36.8 0.0 2.7 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KXH30259.1 - 0.0003 20.6 0.6 0.00081 19.2 0.2 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Pox_T4_N PF04491.12 KXH30259.1 - 0.093 12.6 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Poxvirus T4 protein, N terminus HET PF06985.11 KXH30260.1 - 1.3e-25 90.5 0.0 2.4e-25 89.6 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Tim29 PF10171.9 KXH30260.1 - 0.059 12.9 0.0 0.53 9.8 0.0 2.2 2 0 0 2 2 2 0 Translocase of the Inner Mitochondrial membrane 29 Zn_clus PF00172.18 KXH30261.1 - 8.5e-06 25.8 10.7 1.8e-05 24.8 10.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXH30261.1 - 0.092 11.8 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain DUF1479 PF07350.12 KXH30262.1 - 3.6e-148 493.8 0.0 4.5e-148 493.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) SOG2 PF10428.9 KXH30262.1 - 0.35 10.0 5.7 0.56 9.4 5.7 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein MFS_1 PF07690.16 KXH30263.1 - 9.1e-16 57.7 41.4 9.1e-16 57.7 41.4 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Lactamase_B_2 PF12706.7 KXH30264.1 - 2.4e-08 33.8 0.0 5.2e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DRMBL PF07522.14 KXH30264.1 - 1.8e-06 28.1 0.1 1.4e-05 25.2 0.0 2.4 3 0 0 3 3 3 1 DNA repair metallo-beta-lactamase Lactamase_B PF00753.27 KXH30264.1 - 0.0007 19.7 0.0 0.0047 17.0 0.0 2.1 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily RMMBL PF07521.12 KXH30264.1 - 0.0058 16.5 0.0 0.014 15.3 0.0 1.6 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain MFS_1 PF07690.16 KXH30265.1 - 6.2e-43 147.1 29.1 6.2e-43 147.1 29.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily GCN5L1 PF06320.13 KXH30266.1 - 0.037 14.2 0.2 0.037 14.2 0.2 2.3 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) Seryl_tRNA_N PF02403.22 KXH30266.1 - 0.1 12.9 5.4 1.5 9.1 0.6 2.6 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain XhlA PF10779.9 KXH30266.1 - 0.54 10.5 3.2 0.51 10.6 1.5 1.9 2 0 0 2 2 2 0 Haemolysin XhlA bZIP_1 PF00170.21 KXH30266.1 - 1.4 9.1 10.7 1.5 8.9 4.7 2.6 2 0 0 2 2 2 0 bZIP transcription factor Nup54 PF13874.6 KXH30266.1 - 1.7 8.7 11.4 25 5.0 11.1 2.5 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 Ish1 PF10281.9 KXH30302.1 - 0.069 13.5 0.2 0.18 12.2 0.0 1.7 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein PhoLip_ATPase_N PF16209.5 KXH30302.1 - 0.16 11.7 0.1 0.27 11.0 0.1 1.3 1 0 0 1 1 1 0 Phospholipid-translocating ATPase N-terminal EPSP_synthase PF00275.20 KXH30343.1 - 5e-131 437.2 0.0 9.5e-131 436.3 0.0 1.4 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.20 KXH30343.1 - 1.2e-100 336.1 0.0 1.9e-100 335.4 0.0 1.3 1 0 0 1 1 1 1 3-dehydroquinate synthase DHquinase_I PF01487.15 KXH30343.1 - 2.9e-58 197.8 0.0 5.9e-58 196.8 0.0 1.6 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.22 KXH30343.1 - 9.3e-36 123.3 0.0 2.4e-34 118.8 0.0 2.3 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.11 KXH30343.1 - 4.1e-22 78.2 0.0 8.8e-22 77.2 0.0 1.6 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Fe-ADH_2 PF13685.6 KXH30343.1 - 8.4e-10 38.8 0.0 1.7e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase SDH_C PF18317.1 KXH30343.1 - 0.00021 21.0 0.1 0.00063 19.5 0.1 1.9 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain AAA_22 PF13401.6 KXH30343.1 - 0.053 13.8 0.0 0.16 12.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KXH30343.1 - 0.069 13.3 0.0 0.28 11.3 0.0 2.1 1 0 0 1 1 1 0 AAA domain zf-C2H2 PF00096.26 KXH30344.1 - 5.5e-07 29.7 24.2 0.0061 17.0 1.6 4.3 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXH30344.1 - 1.4 10.0 21.5 1.9 9.5 1.3 4.2 4 0 0 4 4 4 0 C2H2-type zinc finger CKS PF01111.19 KXH30350.1 - 1.8e-34 117.8 1.5 2.4e-34 117.4 1.5 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit Bromodomain PF00439.25 KXH30351.1 - 1e-29 102.4 1.2 8.8e-15 54.6 0.1 2.5 2 0 0 2 2 2 2 Bromodomain Nop14 PF04147.12 KXH30351.1 - 0.012 13.8 11.8 0.021 13.1 11.8 1.3 1 0 0 1 1 1 0 Nop14-like family Astro_capsid_p PF12226.8 KXH30351.1 - 4.9 6.2 10.6 67 2.5 12.3 2.0 2 0 0 2 2 2 0 Turkey astrovirus capsid protein PPP4R2 PF09184.11 KXH30351.1 - 5.4 6.5 14.7 0.5 9.9 8.5 2.2 2 0 0 2 2 2 0 PPP4R2 HMGL-like PF00682.19 KXH30352.1 - 1.4e-79 267.4 0.3 2e-79 266.8 0.3 1.3 1 0 0 1 1 1 1 HMGL-like Nop53 PF07767.11 KXH30353.1 - 0.19 11.1 22.4 0.24 10.7 22.4 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Asp-B-Hydro_N PF05279.11 KXH30353.1 - 1.2 9.2 12.7 1.6 8.7 12.7 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region SRP-alpha_N PF04086.13 KXH30353.1 - 8.4 6.2 17.4 15 5.4 17.4 1.4 1 1 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Thg1 PF04446.12 KXH30354.1 - 4.7e-53 178.5 0.0 7.1e-53 177.9 0.0 1.3 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Thg1C PF14413.6 KXH30354.1 - 2.2e-49 166.7 0.4 3.4e-49 166.1 0.4 1.3 1 0 0 1 1 1 1 Thg1 C terminal domain WD40 PF00400.32 KXH30355.1 - 1.8e-15 57.0 9.6 1e-05 26.1 0.3 5.1 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXH30355.1 - 2.9e-10 40.3 0.7 0.069 13.5 0.0 5.3 2 2 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KXH30355.1 - 2.5e-05 24.2 0.3 0.039 13.8 0.0 3.0 3 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A RNA_pol_Rpb1_1 PF04997.12 KXH30356.1 - 2.2e-106 355.7 0.1 3.6e-106 355.0 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 KXH30356.1 - 9.1e-101 336.8 0.0 1.4e-100 336.2 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 KXH30356.1 - 4.6e-76 254.7 0.0 8.5e-76 253.8 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 KXH30356.1 - 3.6e-62 209.6 5.9 6.5e-62 208.8 5.9 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_7 PF04990.12 KXH30356.1 - 1e-47 161.5 5.5 3.1e-47 160.0 5.3 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_3 PF04983.18 KXH30356.1 - 9.3e-44 149.1 0.0 2.1e-43 147.9 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 KXH30356.1 - 5e-37 126.1 0.1 1.1e-36 125.0 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.13 KXH30356.1 - 0.026 14.9 187.6 0.24 11.8 11.6 12.6 7 2 3 11 11 11 0 RNA polymerase Rpb1 C-terminal repeat CBP_BcsO PF17037.5 KXH30357.1 - 0.043 14.0 0.6 0.043 14.0 0.6 1.0 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsO DUF4682 PF15733.5 KXH30357.1 - 0.14 12.8 1.1 0.24 12.0 1.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4682) DUF676 PF05057.14 KXH30359.1 - 1.3e-42 145.8 0.2 2.8e-27 95.7 0.0 3.2 2 1 1 3 3 3 3 Putative serine esterase (DUF676) PGAP1 PF07819.13 KXH30359.1 - 0.11 12.1 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein DAO PF01266.24 KXH30360.1 - 6.7e-60 203.5 3.8 7.7e-60 203.3 3.8 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXH30360.1 - 4.4e-05 23.6 0.1 9.8e-05 22.5 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KXH30360.1 - 0.0013 18.0 0.0 0.0027 17.0 0.0 1.4 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 KXH30360.1 - 0.026 13.9 0.9 0.11 11.9 0.9 1.8 1 1 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KXH30360.1 - 0.11 11.8 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Mqo PF06039.15 KXH30360.1 - 0.14 10.6 0.0 1.9 7.0 0.0 2.1 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) DUF2415 PF10313.9 KXH30361.1 - 5.3e-13 48.7 0.0 1.3e-12 47.4 0.0 1.7 1 0 0 1 1 1 1 Uncharacterised protein domain (DUF2415) ANAPC4_WD40 PF12894.7 KXH30361.1 - 0.0006 20.1 0.0 0.81 10.0 0.0 3.7 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain HSP70 PF00012.20 KXH30362.1 - 8.6e-267 886.2 15.6 9.9e-267 886.0 15.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KXH30362.1 - 1e-15 57.4 4.1 9.4e-14 51.0 0.8 2.4 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 KXH30362.1 - 0.00044 20.0 0.0 0.0013 18.5 0.0 1.9 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Ploopntkinase3 PF18751.1 KXH30362.1 - 0.029 14.3 0.2 2.3 8.1 0.0 2.4 1 1 1 2 2 2 0 P-loop Nucleotide Kinase3 ApoLp-III PF07464.11 KXH30362.1 - 7.3 6.7 9.4 1.1 9.4 3.2 2.6 2 1 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) SRP68 PF16969.5 KXH30363.1 - 2.1e-203 677.4 16.1 2.4e-203 677.2 16.1 1.0 1 0 0 1 1 1 1 RNA-binding signal recognition particle 68 P4Ha_N PF08336.11 KXH30363.1 - 0.034 14.2 0.2 0.15 12.1 0.0 2.2 2 1 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region CENP-O PF09496.10 KXH30363.1 - 0.052 13.5 5.4 0.13 12.2 0.6 3.0 3 0 0 3 3 3 0 Cenp-O kinetochore centromere component DUF755 PF05501.11 KXH30363.1 - 0.21 11.9 0.0 0.21 11.9 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF755) Rab_bind PF16704.5 KXH30363.1 - 0.26 11.3 2.4 4 7.5 0.0 3.2 3 0 0 3 3 3 0 Rab binding domain Mis14 PF08641.12 KXH30363.1 - 0.34 11.2 3.7 0.58 10.5 0.1 3.0 2 1 0 3 3 3 0 Kinetochore protein Mis14 like PPR_2 PF13041.6 KXH30364.1 - 4.5e-17 62.0 0.0 1.3e-06 28.5 0.0 6.6 4 1 2 6 6 6 3 PPR repeat family PPR PF01535.20 KXH30364.1 - 7.6e-13 47.8 0.9 0.0016 18.5 0.0 7.4 8 0 0 8 8 7 1 PPR repeat PPR_3 PF13812.6 KXH30364.1 - 6.1e-08 32.6 0.0 0.0052 16.8 0.0 4.5 2 1 3 5 5 5 1 Pentatricopeptide repeat domain PPR_1 PF12854.7 KXH30364.1 - 4.4e-06 26.3 0.0 1.7 8.4 0.0 5.4 6 0 0 6 6 6 2 PPR repeat TPR_14 PF13428.6 KXH30364.1 - 0.0004 21.0 11.2 12 7.0 0.0 7.7 6 1 1 7 7 6 1 Tetratricopeptide repeat ELYS PF13934.6 KXH30364.1 - 0.006 16.6 0.7 0.35 10.8 0.0 2.7 2 0 0 2 2 2 1 Nuclear pore complex assembly TPR_2 PF07719.17 KXH30364.1 - 0.0096 16.0 6.6 3.3 8.0 0.2 4.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KXH30364.1 - 0.021 14.6 1.2 13 5.8 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 KXH30364.1 - 0.051 13.9 1.2 3.4 8.0 0.0 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat AEP1 PF17049.5 KXH30364.1 - 0.19 10.7 0.0 0.39 9.8 0.0 1.4 1 0 0 1 1 1 0 ATPase expression protein 1 TPR_16 PF13432.6 KXH30364.1 - 6.4 7.5 8.4 9 7.0 0.1 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 KXH30364.1 - 6.6 6.7 12.4 6.4 6.8 0.1 4.6 5 0 0 5 5 4 0 Tetratricopeptide repeat BTAD PF03704.17 KXH30364.1 - 6.6 7.2 13.5 7.2 7.0 0.0 4.3 4 0 0 4 4 4 0 Bacterial transcriptional activator domain Cutinase PF01083.22 KXH30365.1 - 2.7e-40 138.2 0.0 3.5e-40 137.8 0.0 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 KXH30365.1 - 0.016 14.8 0.0 0.027 14.0 0.0 1.3 1 0 0 1 1 1 0 PE-PPE domain Abhydrolase_8 PF06259.12 KXH30365.1 - 0.018 14.7 0.2 0.033 13.8 0.2 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase Lipase_3 PF01764.25 KXH30365.1 - 0.035 14.0 0.0 0.059 13.2 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF2974 PF11187.8 KXH30365.1 - 0.039 13.5 0.0 0.06 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DUF4210 PF13915.6 KXH30366.1 - 6.9e-33 113.1 0.0 1.7e-32 111.8 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.6 KXH30366.1 - 1.6e-22 79.4 0.4 3.1e-22 78.5 0.4 1.5 1 0 0 1 1 1 1 Chromosome segregation during meiosis Nup35_RRM_2 PF14605.6 KXH30367.1 - 3.4e-09 36.5 0.0 0.0039 17.1 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_1 PF00076.22 KXH30367.1 - 1.2e-08 34.7 0.2 2.7e-07 30.3 0.1 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PWI PF01480.17 KXH30367.1 - 1.4e-07 31.7 0.0 4.4e-07 30.1 0.0 1.8 2 0 0 2 2 1 1 PWI domain zf-CCCH PF00642.24 KXH30367.1 - 6.7e-06 25.9 2.9 1.2e-05 25.0 2.9 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KXH30367.1 - 0.00017 21.5 4.6 0.00031 20.7 4.6 1.4 1 0 0 1 1 1 1 Zinc finger domain PHM7_cyt PF14703.6 KXH30367.1 - 0.0055 17.0 6.3 0.0072 16.6 0.0 3.0 3 0 0 3 3 3 1 Cytosolic domain of 10TM putative phosphate transporter Torus PF16131.5 KXH30367.1 - 0.15 12.8 0.1 0.15 12.8 0.1 2.2 2 0 0 2 2 2 0 Torus domain Atg14 PF10186.9 KXH30367.1 - 0.2 10.7 4.7 0.4 9.7 4.7 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 zf-CCCH_4 PF18044.1 KXH30367.1 - 0.4 10.5 4.6 0.68 9.8 4.6 1.4 1 0 0 1 1 1 0 CCCH-type zinc finger Borrelia_P83 PF05262.11 KXH30367.1 - 0.87 8.0 16.2 0.92 7.9 15.7 1.3 1 1 0 1 1 1 0 Borrelia P83/100 protein RRM_3 PF08777.11 KXH30367.1 - 1.2 9.2 9.3 4.6 7.4 3.8 3.2 2 1 1 3 3 3 0 RNA binding motif RNA_polI_A14 PF08203.11 KXH30367.1 - 1.7 9.4 5.5 29 5.5 0.0 3.0 2 0 0 2 2 2 0 Yeast RNA polymerase I subunit RPA14 Seryl_tRNA_N PF02403.22 KXH30367.1 - 5.5 7.3 12.8 14 5.9 12.8 1.6 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain LegC3_N PF18654.1 KXH30367.1 - 5.7 6.1 16.0 9.4 5.4 0.9 2.2 2 0 0 2 2 2 0 LegC3 N-terminal coiled-coil domain DUF4407 PF14362.6 KXH30367.1 - 6.6 6.0 13.6 10 5.4 11.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) GTP_EFTU PF00009.27 KXH30368.1 - 1.9e-66 223.3 0.4 2.8e-66 222.8 0.4 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 KXH30368.1 - 2.3e-32 111.3 0.0 6.3e-32 109.9 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 KXH30368.1 - 8.5e-23 80.2 0.0 2.8e-22 78.6 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KXH30368.1 - 7.2e-13 48.7 1.6 1.4e-12 47.8 0.1 2.4 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_II PF14492.6 KXH30368.1 - 5.1e-12 45.7 0.0 1.7e-11 44.0 0.0 1.9 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 KXH30368.1 - 0.00026 21.0 0.4 0.00075 19.6 0.4 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 KXH30368.1 - 0.05 13.4 0.2 0.18 11.5 0.1 1.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Solute_trans_a PF03619.16 KXH30370.1 - 4.3e-99 331.3 9.5 5.2e-99 331.1 9.5 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DUF4293 PF14126.6 KXH30370.1 - 0.066 13.5 0.9 0.15 12.3 0.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4293) Glyco_hydro_92 PF07971.12 KXH30371.1 - 3.4e-135 451.6 0.1 4.1e-135 451.3 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 KXH30371.1 - 3.6e-49 167.8 2.5 6.2e-49 167.0 2.5 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain Acetyltransf_1 PF00583.25 KXH30371.1 - 0.031 14.5 0.0 0.079 13.2 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Zn_clus PF00172.18 KXH30372.1 - 0.12 12.5 7.7 0.32 11.2 7.7 1.7 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Sec5 PF15469.6 KXH30373.1 - 6.6e-40 136.9 0.0 2.2e-39 135.2 0.0 2.0 2 0 0 2 2 2 1 Exocyst complex component Sec5 Vps51 PF08700.11 KXH30373.1 - 0.00025 21.0 2.3 0.00046 20.2 0.1 2.6 2 0 0 2 2 2 1 Vps51/Vps67 Sec15 PF04091.12 KXH30373.1 - 0.0054 16.2 0.1 0.01 15.3 0.1 1.3 1 0 0 1 1 1 1 Exocyst complex subunit Sec15-like Iso_dh PF00180.20 KXH30374.1 - 4.4e-99 331.9 0.0 5.2e-99 331.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Phage_30_3 PF08010.11 KXH30374.1 - 0.0067 16.2 0.0 0.014 15.2 0.0 1.4 1 0 0 1 1 1 1 Bacteriophage protein GP30.3 GFO_IDH_MocA PF01408.22 KXH30375.1 - 4.8e-24 85.5 0.0 7.8e-24 84.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 KXH30375.1 - 7.4e-06 26.6 0.1 2.8e-05 24.7 0.0 1.9 2 0 0 2 2 2 1 Homoserine dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 KXH30376.1 - 2.4e-63 214.5 0.0 6.6e-63 213.1 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KXH30376.1 - 1.9e-07 31.0 0.1 0.0043 16.7 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 KXH30376.1 - 0.01 16.4 0.0 0.59 10.7 0.0 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXH30376.1 - 0.025 14.8 0.0 0.068 13.4 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXH30376.1 - 0.1 11.8 0.0 2.3 7.4 0.0 2.5 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXH30377.1 - 1.5e-50 172.1 3.2 2e-50 171.7 3.2 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.26 KXH30377.1 - 1.9e-14 53.4 0.0 4.5e-14 52.1 0.0 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox PF00070.27 KXH30377.1 - 1.7e-13 50.9 1.2 1.7e-13 50.9 1.2 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Reductase_C PF14759.6 KXH30377.1 - 4.8e-06 27.0 0.0 1.3e-05 25.7 0.0 1.8 1 0 0 1 1 1 1 Reductase C-terminal Rieske_2 PF13806.6 KXH30377.1 - 0.00019 21.3 0.0 0.00066 19.6 0.0 1.9 2 0 0 2 2 2 1 Rieske-like [2Fe-2S] domain K_oxygenase PF13434.6 KXH30377.1 - 0.00083 18.6 0.0 0.7 9.0 0.0 2.5 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KXH30377.1 - 0.0072 16.3 2.9 1.2 9.1 0.0 3.0 3 0 0 3 3 3 2 FAD-NAD(P)-binding DUF1188 PF06690.11 KXH30377.1 - 0.023 14.3 0.1 0.034 13.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1188) FIST PF08495.10 KXH30377.1 - 0.074 13.1 0.3 0.33 10.9 0.0 2.1 2 0 0 2 2 2 0 FIST N domain Fungal_trans PF04082.18 KXH30378.1 - 5.6e-21 74.8 0.0 9e-21 74.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH30378.1 - 5.5e-08 32.8 7.3 5.5e-08 32.8 7.3 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MSG PF02349.15 KXH30378.1 - 0.067 13.4 4.1 1 9.6 0.0 2.3 2 0 0 2 2 2 0 Major surface glycoprotein Oxidored_FMN PF00724.20 KXH30379.1 - 2.9e-28 99.1 0.1 1.7e-27 96.6 0.0 1.9 1 1 0 2 2 2 1 NADH:flavin oxidoreductase / NADH oxidase family ADH_N PF08240.12 KXH30381.1 - 1.5e-24 85.9 1.9 2.8e-24 85.1 1.9 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_assoc PF13823.6 KXH30381.1 - 9.3e-11 41.5 0.8 9.3e-11 41.5 0.8 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-associated ADH_zinc_N PF00107.26 KXH30381.1 - 6.5e-08 32.6 0.0 8.1e-06 25.8 0.0 2.6 2 0 0 2 2 2 2 Zinc-binding dehydrogenase Sugar_tr PF00083.24 KXH30382.1 - 6.7e-121 404.3 22.0 7.7e-121 404.1 22.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH30382.1 - 3.6e-18 65.6 31.0 3.6e-18 65.6 31.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TPR_19 PF14559.6 KXH30382.1 - 0.14 12.7 0.0 0.27 11.8 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat Baculo_VP91_N PF08475.10 KXH30383.1 - 0.2 11.3 0.0 0.29 10.8 0.0 1.1 1 0 0 1 1 1 0 Viral capsid protein 91 N-terminal Glyco_hydro_61 PF03443.14 KXH30384.1 - 1.1e-42 146.3 0.1 4.6e-42 144.3 0.1 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 Peptidase_C53 PF05550.11 KXH30384.1 - 0.14 11.8 0.0 0.33 10.6 0.0 1.6 2 0 0 2 2 2 0 Pestivirus Npro endopeptidase C53 Glyco_hydro_61 PF03443.14 KXH30385.1 - 7e-09 35.9 0.0 8.4e-09 35.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Ilm1 PF10311.9 KXH30385.1 - 0.18 11.4 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 Increased loss of mitochondrial DNA protein 1 bZIP_1 PF00170.21 KXH30386.1 - 7.6e-06 25.9 11.1 1.2e-05 25.3 11.1 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KXH30386.1 - 0.053 13.6 9.1 0.089 12.9 9.1 1.4 1 0 0 1 1 1 0 Basic region leucine zipper Macoilin PF09726.9 KXH30386.1 - 0.091 11.3 4.5 0.11 11.0 4.5 1.0 1 0 0 1 1 1 0 Macoilin family CDC45 PF02724.14 KXH30386.1 - 0.54 8.5 5.1 0.62 8.3 5.1 1.1 1 0 0 1 1 1 0 CDC45-like protein NRBF2 PF08961.10 KXH30386.1 - 0.79 9.3 5.7 0.13 11.9 1.7 1.6 2 0 0 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator SRAP PF02586.14 KXH30387.1 - 4.4e-81 271.6 0.0 6.2e-81 271.1 0.0 1.2 1 0 0 1 1 1 1 SOS response associated peptidase (SRAP) Tannase PF07519.11 KXH30388.1 - 6.5e-106 355.0 1.3 8.2e-106 354.7 1.3 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase RNA_pol_Rpb1_1 PF04997.12 KXH30389.1 - 3e-84 283.0 0.1 5.2e-84 282.2 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 KXH30389.1 - 2.5e-78 263.2 0.2 4.2e-78 262.5 0.2 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 KXH30389.1 - 3.4e-73 245.3 0.0 6.8e-73 244.3 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 KXH30389.1 - 5.1e-40 137.0 0.0 1.4e-39 135.6 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 KXH30389.1 - 2.1e-29 101.6 0.1 6.6e-29 100.0 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 DDHD PF02862.17 KXH30390.1 - 1.2e-63 215.3 0.0 1.2e-63 215.3 0.0 2.7 3 1 0 3 3 3 1 DDHD domain Abhydrolase_6 PF12697.7 KXH30390.1 - 0.058 14.0 0.0 0.11 13.1 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family LIDHydrolase PF10230.9 KXH30390.1 - 0.062 12.9 0.0 0.16 11.5 0.0 1.6 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Lipase_3 PF01764.25 KXH30390.1 - 0.12 12.2 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) Ank_2 PF12796.7 KXH30391.1 - 0.0015 19.0 0.0 0.006 17.2 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) zf-RING_2 PF13639.6 KXH30391.1 - 0.0044 17.3 2.6 0.0044 17.3 2.6 1.5 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.6 KXH30391.1 - 0.051 13.7 3.4 0.11 12.7 3.4 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 KXH30391.1 - 1.1 9.4 6.0 1.8 8.6 5.8 1.6 1 1 0 1 1 1 0 RING-type zinc-finger CH PF00307.31 KXH30392.1 - 1.2e-64 215.2 0.0 5.6e-17 61.9 0.0 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.6 KXH30392.1 - 3e-06 27.6 0.2 4.5e-05 23.8 0.0 2.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 KXH30392.1 - 1.5e-05 24.2 0.5 1.6 8.4 0.1 3.6 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 KXH30392.1 - 0.057 13.4 0.2 6 7.1 0.0 3.3 3 0 0 3 3 3 0 EF-hand domain MBOAT PF03062.19 KXH30393.1 - 1.9e-42 145.9 22.1 1.9e-42 145.9 22.1 2.4 2 1 0 2 2 2 2 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 KXH30393.1 - 6.1e-06 26.4 5.5 1.5e-05 25.2 5.5 1.6 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family RRM_1 PF00076.22 KXH30394.1 - 1.2e-11 44.3 0.0 2.2e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KXH30394.1 - 0.00026 20.9 0.0 0.00041 20.3 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Ribosomal_L18 PF17135.4 KXH30395.1 - 1.8e-91 304.7 2.9 2.3e-91 304.3 2.9 1.1 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Mito_carr PF00153.27 KXH30395.1 - 6.3e-71 234.4 3.4 1.4e-23 82.6 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KXH30395.1 - 0.00047 19.4 0.4 0.008 15.4 0.0 2.8 3 1 1 4 4 4 1 Gammaproteobacterial serine protease Ribosomal_L27A PF00828.19 KXH30395.1 - 0.003 18.2 0.1 0.0099 16.6 0.1 1.9 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A zinc_ribbon_15 PF17032.5 KXH30397.1 - 8.5 7.2 11.2 10 7.0 5.5 2.9 3 1 0 3 3 3 0 zinc-ribbon family DivIVA PF05103.13 KXH30399.1 - 0.12 12.4 25.8 0.49 10.5 4.4 3.5 2 1 1 3 3 3 0 DivIVA protein DUF2046 PF09755.9 KXH30399.1 - 0.96 8.6 26.1 0.6 9.3 24.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) CHD5 PF04420.14 KXH30399.1 - 2.8 7.8 6.0 2.5 7.9 4.4 1.7 1 1 0 1 1 1 0 CHD5-like protein Tropomyosin_1 PF12718.7 KXH30399.1 - 7.1 6.8 29.8 4.6 7.4 13.2 2.6 1 1 1 2 2 2 0 Tropomyosin like Rft-1 PF04506.13 KXH30400.1 - 1.9e-149 498.7 11.7 2.1e-149 498.6 11.7 1.0 1 0 0 1 1 1 1 Rft protein Polysacc_synt_3 PF13440.6 KXH30400.1 - 0.018 14.3 0.8 0.018 14.3 0.8 3.2 2 1 1 3 3 3 0 Polysaccharide biosynthesis protein Urb2 PF10441.9 KXH30400.1 - 0.018 15.0 0.4 0.036 14.0 0.4 1.5 1 0 0 1 1 1 0 Urb2/Npa2 family DEAD PF00270.29 KXH30401.1 - 1.9e-50 171.1 0.0 7.6e-50 169.1 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXH30401.1 - 1.7e-34 118.5 0.0 1.3e-30 106.0 0.0 2.9 3 0 0 3 3 3 2 Helicase conserved C-terminal domain UTP25 PF06862.12 KXH30401.1 - 0.011 14.5 0.0 0.042 12.6 0.0 1.9 2 0 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Presenilin PF01080.17 KXH30401.1 - 0.25 10.1 12.2 0.36 9.5 12.2 1.2 1 0 0 1 1 1 0 Presenilin Zip PF02535.22 KXH30401.1 - 0.46 9.7 6.0 0.66 9.1 6.0 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Gti1_Pac2 PF09729.9 KXH30401.1 - 0.8 9.8 8.0 1.6 8.8 8.0 1.7 1 0 0 1 1 1 0 Gti1/Pac2 family DUF966 PF06136.13 KXH30401.1 - 3 7.5 19.0 5.3 6.7 19.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF966) TAF4 PF05236.14 KXH30401.1 - 3 7.5 25.4 5.1 6.7 25.4 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family DUF4778 PF16008.5 KXH30401.1 - 4.1 7.4 9.3 6.9 6.6 9.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) SOBP PF15279.6 KXH30401.1 - 4.2 7.9 5.8 6.7 7.2 5.8 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein LYRIC PF15686.5 KXH30401.1 - 4.9 6.6 32.7 8.6 5.8 32.7 1.3 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family DUF4551 PF15087.6 KXH30401.1 - 8.6 5.1 11.3 13 4.5 11.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) SUR7 PF06687.12 KXH30402.1 - 2.8 7.5 13.5 16 5.1 10.1 3.1 2 1 1 3 3 3 0 SUR7/PalI family adh_short PF00106.25 KXH30403.1 - 1.2e-20 73.8 0.0 1.3e-16 60.6 0.1 2.3 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXH30403.1 - 3.8e-12 46.3 0.1 2.4e-09 37.1 0.0 2.4 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH30403.1 - 9.5e-08 32.2 0.2 2e-07 31.1 0.2 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXH30403.1 - 0.0043 16.5 0.2 0.0082 15.6 0.2 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KXH30403.1 - 0.04 13.1 0.0 0.056 12.6 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NifU_N PF01592.16 KXH30404.1 - 3.3e-52 176.0 0.0 4.4e-52 175.6 0.0 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain UCH PF00443.29 KXH30405.1 - 2.6e-35 122.2 0.0 4.5e-35 121.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP_var PF17807.1 KXH30405.1 - 2.3e-23 81.7 1.3 5.9e-22 77.2 0.1 2.5 2 0 0 2 2 2 1 Variant UBP zinc finger UBA PF00627.31 KXH30405.1 - 7.3e-23 80.1 0.3 1.3e-11 44.2 0.3 2.6 2 0 0 2 2 2 2 UBA/TS-N domain zf-UBP PF02148.19 KXH30405.1 - 5.9e-22 77.8 13.9 1.8e-19 69.8 2.2 3.3 3 0 0 3 3 3 2 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 KXH30405.1 - 6.5e-17 62.1 1.1 1.1e-14 54.8 0.0 3.5 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase UBA_3 PF09288.10 KXH30405.1 - 0.058 13.2 0.0 1.2 9.0 0.0 3.0 3 0 0 3 3 3 0 Fungal ubiquitin-associated domain UBA_4 PF14555.6 KXH30405.1 - 0.091 12.6 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 UBA-like domain HORMA PF02301.18 KXH30406.1 - 4.2e-34 118.0 0.0 5.6e-34 117.6 0.0 1.2 1 0 0 1 1 1 1 HORMA domain BUD22 PF09073.10 KXH30406.1 - 0.00031 20.2 2.5 0.00043 19.7 2.5 1.1 1 0 0 1 1 1 1 BUD22 ATG101 PF07855.12 KXH30406.1 - 0.0005 20.1 0.4 0.0025 17.8 0.4 2.1 1 1 0 1 1 1 1 Autophagy-related protein 101 DUF3530 PF12048.8 KXH30406.1 - 0.026 14.0 2.6 0.18 11.2 1.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3530) MID_MedPIWI PF18296.1 KXH30406.1 - 0.041 13.7 0.2 0.07 12.9 0.2 1.4 1 0 0 1 1 1 0 MID domain of medPIWI DUF2660 PF10859.8 KXH30406.1 - 0.042 14.3 0.1 0.089 13.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2660) Stirrup PF09061.6 KXH30406.1 - 0.11 12.7 0.0 0.91 9.8 0.0 2.1 2 0 0 2 2 2 0 Stirrup Med21 PF11221.8 KXH30406.1 - 0.42 10.9 4.3 0.11 12.7 0.9 1.7 2 0 0 2 2 2 0 Subunit 21 of Mediator complex FlaG PF03646.15 KXH30406.1 - 4.3 7.6 9.5 28 5.0 1.4 3.2 3 0 0 3 3 3 0 FlaG protein Fungal_trans PF04082.18 KXH30407.1 - 5.4e-33 114.2 0.0 9.7e-33 113.3 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH30407.1 - 1.2e-09 38.1 9.5 2.5e-09 37.1 9.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CCDC53 PF10152.9 KXH30407.1 - 0.69 10.3 3.9 7.5 7.0 0.1 2.2 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex DUF1525 PF07511.11 KXH30407.1 - 1.6 8.9 8.7 0.41 10.8 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1525) Metallophos PF00149.28 KXH30408.1 - 4.8e-10 40.3 0.0 7.2e-10 39.7 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KXH30408.1 - 7.5e-05 23.0 0.0 0.0014 18.8 0.0 2.1 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain EstA_Ig_like PF18435.1 KXH30408.1 - 0.15 12.2 0.0 0.24 11.6 0.0 1.3 1 0 0 1 1 1 0 Esterase Ig-like N-terminal domain Tyrosinase PF00264.20 KXH30409.1 - 8.7e-51 173.3 1.6 1.3e-50 172.8 1.6 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase DiS_P_DiS PF06750.13 KXH30409.1 - 0.05 13.7 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Bacterial Peptidase A24 N-terminal domain RPE65 PF03055.15 KXH30410.1 - 9.9e-114 381.1 0.0 1.1e-113 380.9 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Glyco_hydro_31 PF01055.26 KXH30411.1 - 1.1e-107 361.0 5.4 3.4e-107 359.4 5.4 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 KXH30411.1 - 2.6e-08 34.0 0.8 1e-07 32.2 0.8 2.1 1 0 0 1 1 1 1 Galactose mutarotase-like DUF5110 PF17137.4 KXH30411.1 - 0.00011 22.4 0.0 0.0057 16.9 0.0 2.8 2 0 0 2 2 2 1 Domain of unknown function (DUF5110) AUDH_Cupin PF18637.1 KXH30412.1 - 1.4e-61 207.1 4.8 2.1e-61 206.5 4.8 1.3 1 0 0 1 1 1 1 Aldos-2-ulose dehydratase/isomerase (AUDH) Cupin domain PBP3 PF18056.1 KXH30412.1 - 5.4e-29 100.5 0.0 8.4e-29 99.9 0.0 1.3 1 0 0 1 1 1 1 Penicillin Binding Protein 3 Domain VCBS PF13517.6 KXH30412.1 - 1.1e-05 25.9 2.3 0.6 10.7 0.0 4.4 5 0 0 5 5 5 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 KXH30412.1 - 0.012 15.7 6.3 1.3 9.2 0.0 2.6 2 0 0 2 2 2 0 FG-GAP repeat Fungal_trans PF04082.18 KXH30413.1 - 1.2e-14 54.1 0.0 2e-14 53.3 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain PT PF04886.12 KXH30414.1 - 0.00019 20.9 4.9 0.00019 20.9 4.9 2.7 3 0 0 3 3 3 1 PT repeat Aa_trans PF01490.18 KXH30416.1 - 2.5e-54 184.6 41.1 2.8e-54 184.4 41.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Fungal_trans_2 PF11951.8 KXH30418.1 - 1.8e-13 50.1 0.1 9.3e-09 34.6 0.0 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH30419.1 - 0.0028 17.7 2.1 0.0028 17.7 2.1 2.9 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXH30419.1 - 0.0042 16.2 0.1 0.0085 15.2 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain NAD_binding_10 PF13460.6 KXH30421.1 - 1.2e-07 31.8 0.1 2.3e-07 30.9 0.1 1.5 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KXH30421.1 - 4.8e-07 29.6 0.0 7.5e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 KXH30421.1 - 0.062 12.8 0.0 0.35 10.3 0.0 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family FAD_binding_3 PF01494.19 KXH30422.1 - 3.3e-08 33.2 0.1 1e-07 31.6 0.1 1.8 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KXH30422.1 - 0.0012 18.5 0.3 0.0042 16.7 0.1 1.8 1 1 1 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXH30422.1 - 0.0028 17.8 0.1 0.0092 16.2 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KXH30422.1 - 0.15 11.1 0.9 12 4.8 0.0 2.3 3 0 0 3 3 3 0 Lycopene cyclase protein NmrA PF05368.13 KXH30423.1 - 1.6e-35 122.7 0.0 2.9e-35 121.9 0.0 1.3 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXH30423.1 - 1.6e-11 44.5 0.0 2.2e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KXH30423.1 - 0.0002 20.9 0.0 0.00037 20.0 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 KXH30423.1 - 0.0004 20.6 0.1 0.00071 19.8 0.1 1.4 1 0 0 1 1 1 1 TrkA-N domain 3Beta_HSD PF01073.19 KXH30423.1 - 0.033 13.2 0.0 0.043 12.8 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 KXH30424.1 - 1.6e-17 63.9 0.1 2e-17 63.5 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXH30424.1 - 2.4e-13 50.4 0.0 4.7e-13 49.4 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KXH30424.1 - 0.001 19.4 0.1 0.0041 17.4 0.0 1.9 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain ADH_zinc_N PF00107.26 KXH30425.1 - 4e-13 49.5 0.0 7.3e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXH30425.1 - 2.9e-06 27.1 0.9 8.2e-06 25.7 0.9 1.7 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KXH30425.1 - 0.0002 22.4 0.0 0.00036 21.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Bap31_Bap29_C PF18035.1 KXH30426.1 - 0.0004 20.3 2.8 0.00091 19.2 2.8 1.5 1 0 0 1 1 1 1 Bap31/Bap29 cytoplasmic coiled-coil domain DUF3552 PF12072.8 KXH30426.1 - 0.069 12.6 1.6 0.11 11.8 1.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) HSP70 PF00012.20 KXH30427.1 - 0.00029 19.2 0.1 0.0015 16.8 0.1 1.9 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KXH30427.1 - 0.0039 16.1 0.8 0.042 12.7 0.2 2.1 2 0 0 2 2 2 1 MreB/Mbl protein GCV_T PF01571.21 KXH30428.1 - 7.6e-66 222.1 0.0 1.5e-65 221.1 0.0 1.5 2 0 0 2 2 2 1 Aminomethyltransferase folate-binding domain DAO PF01266.24 KXH30428.1 - 1e-47 163.5 1.5 1.5e-47 162.9 1.5 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAO_M PF16350.5 KXH30428.1 - 3.5e-19 68.9 0.0 7.1e-19 67.9 0.0 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase central domain GCV_T_C PF08669.11 KXH30428.1 - 1.6e-18 66.4 0.0 4.6e-18 64.9 0.0 1.9 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain Pyr_redox_2 PF07992.14 KXH30428.1 - 8.6e-06 25.2 0.2 0.08 12.2 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXH30428.1 - 4.4e-05 22.8 0.3 0.0001 21.5 0.3 1.6 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 KXH30428.1 - 0.00013 22.4 0.6 0.083 13.5 0.2 2.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KXH30428.1 - 0.0012 17.7 0.9 0.017 14.0 0.0 2.1 2 0 0 2 2 2 1 Tryptophan halogenase TrkA_N PF02254.18 KXH30428.1 - 0.0024 18.1 0.1 0.016 15.5 0.1 2.3 3 0 0 3 3 2 1 TrkA-N domain Shikimate_DH PF01488.20 KXH30428.1 - 0.0067 16.5 0.1 0.015 15.4 0.1 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.6 KXH30428.1 - 0.012 15.6 0.9 0.66 10.0 0.1 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding ThiF PF00899.21 KXH30428.1 - 0.014 14.7 0.0 0.028 13.8 0.0 1.4 1 0 0 1 1 1 0 ThiF family HI0933_like PF03486.14 KXH30428.1 - 0.034 12.8 0.1 0.13 10.9 0.0 1.8 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_3 PF13738.6 KXH30428.1 - 0.088 12.1 0.3 3.5 6.8 0.2 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXH30428.1 - 0.14 12.4 0.0 0.43 10.9 0.0 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Adeno_100 PF02438.16 KXH30429.1 - 0.14 10.3 0.1 0.15 10.2 0.1 1.0 1 0 0 1 1 1 0 Late 100kD protein DAO PF01266.24 KXH30430.1 - 6.1e-29 101.7 0.0 8.8e-29 101.2 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Fungal_trans PF04082.18 KXH30430.1 - 3.9e-07 29.4 0.9 7.1e-07 28.5 0.9 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain NAD_binding_8 PF13450.6 KXH30430.1 - 0.0015 18.7 0.0 0.0043 17.3 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KXH30430.1 - 0.0021 18.0 0.0 0.045 13.7 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KXH30430.1 - 0.018 14.3 0.0 0.22 10.7 0.0 2.1 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GP3_package PF16677.5 KXH30430.1 - 0.083 13.0 0.0 0.93 9.7 0.0 2.4 2 0 0 2 2 2 0 DNA-packaging protein gp3 Ring_hydroxyl_A PF00848.19 KXH30431.1 - 6.5e-23 81.8 6.7 1.3e-19 71.0 6.7 2.3 1 1 0 1 1 1 1 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.26 KXH30431.1 - 1.2e-16 60.4 0.1 3.4e-16 58.9 0.0 1.8 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain CorC_HlyC PF03471.17 KXH30431.1 - 0.14 12.2 0.0 0.41 10.7 0.0 1.8 2 0 0 2 2 2 0 Transporter associated domain UNC-93 PF05978.16 KXH30432.1 - 1e-14 54.5 2.0 1e-14 54.5 2.0 2.6 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 KXH30432.1 - 3.6e-14 52.5 19.4 3.6e-14 52.5 19.4 2.1 1 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH30432.1 - 0.035 13.0 19.2 0.015 14.2 6.0 2.7 2 1 1 3 3 3 0 Sugar (and other) transporter OATP PF03137.20 KXH30432.1 - 0.04 12.2 7.1 0.68 8.2 0.7 2.3 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DAO PF01266.24 KXH30438.1 - 8.2e-31 107.9 0.0 9.7e-31 107.6 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KXH30438.1 - 3.7e-08 32.7 0.3 0.00085 18.3 0.0 2.6 2 1 1 3 3 3 2 Tryptophan halogenase NAD_binding_9 PF13454.6 KXH30438.1 - 3e-05 24.1 0.1 0.092 12.7 0.0 2.6 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KXH30438.1 - 6.6e-05 22.3 0.1 0.15 11.2 0.0 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.19 KXH30438.1 - 0.00042 19.8 0.1 0.11 11.9 0.0 2.3 2 0 0 2 2 2 2 GMC oxidoreductase Pyr_redox PF00070.27 KXH30438.1 - 0.0021 18.6 0.0 0.84 10.2 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KXH30438.1 - 0.005 16.0 0.0 0.078 12.0 0.0 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 KXH30438.1 - 0.0055 16.9 0.0 0.013 15.7 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Sacchrp_dh_NADP PF03435.18 KXH30438.1 - 0.031 14.5 0.0 0.097 12.9 0.0 1.9 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 KXH30438.1 - 0.085 13.1 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_7 PF13241.6 KXH30438.1 - 0.11 13.0 0.0 0.2 12.1 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding p450 PF00067.22 KXH30439.1 - 7.5e-64 216.2 0.0 9.4e-64 215.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 AMP-binding PF00501.28 KXH30440.1 - 4.4e-50 170.5 0.0 5.6e-50 170.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Thioesterase PF00975.20 KXH30440.1 - 1.8e-27 96.9 0.1 7.3e-27 95.0 0.1 2.1 1 1 0 1 1 1 1 Thioesterase domain PP-binding PF00550.25 KXH30440.1 - 5.1e-11 42.8 0.1 1.1e-10 41.7 0.1 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site PV_NSP1 PF12433.8 KXH30440.1 - 0.039 14.3 0.0 0.081 13.3 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein 1 Aldedh PF00171.22 KXH30441.1 - 1.5e-182 607.3 0.0 1.7e-182 607.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family AA_permease_2 PF13520.6 KXH30442.1 - 3.3e-53 181.0 50.7 4.3e-53 180.7 50.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXH30442.1 - 1.7e-18 66.5 41.2 2.2e-18 66.1 41.2 1.1 1 0 0 1 1 1 1 Amino acid permease DUF1294 PF06961.13 KXH30442.1 - 0.085 13.1 0.1 0.39 11.0 0.1 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1294) DUF3493 PF11998.8 KXH30442.1 - 0.28 11.4 0.0 0.28 11.4 0.0 3.2 3 0 0 3 3 3 0 Low psii accumulation1 / Rep27 Cu_amine_oxid PF01179.20 KXH30443.1 - 3.4e-151 503.8 0.0 4.2e-151 503.5 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 KXH30443.1 - 2.4e-19 69.6 0.0 7.7e-19 68.0 0.0 1.9 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 KXH30443.1 - 2.3e-12 46.9 0.1 4.4e-12 46.1 0.1 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain DUF4105 PF13387.6 KXH30443.1 - 0.027 14.1 0.1 0.064 12.9 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4105) Fungal_trans_2 PF11951.8 KXH30444.1 - 3.2e-25 88.8 0.0 4.4e-25 88.3 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH30444.1 - 2.6e-08 33.9 11.1 6.9e-08 32.5 11.1 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SnoaL_2 PF12680.7 KXH30445.1 - 8.1e-06 26.4 0.1 8.6e-05 23.1 0.0 2.3 2 0 0 2 2 2 1 SnoaL-like domain SnoaL PF07366.12 KXH30445.1 - 1.1e-05 25.2 0.0 2.2e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase Chromate_transp PF02417.15 KXH30446.1 - 1.9e-58 197.1 29.9 3.5e-33 115.0 11.0 2.7 3 0 0 3 3 3 2 Chromate transporter KTI12 PF08433.10 KXH30451.1 - 0.026 14.0 0.0 0.044 13.2 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 GATase PF00117.28 KXH30452.1 - 1.5e-47 161.9 0.0 1.9e-47 161.5 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.22 KXH30452.1 - 2.5e-46 156.7 0.0 3.7e-46 156.1 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain Peptidase_C26 PF07722.13 KXH30452.1 - 5.2e-05 23.1 0.3 0.0046 16.7 0.3 2.7 1 1 0 1 1 1 1 Peptidase C26 MFS_1 PF07690.16 KXH30453.1 - 2.3e-25 89.3 21.4 4.4e-25 88.4 21.4 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Rad51 PF08423.11 KXH30453.1 - 0.056 12.7 0.0 0.1 11.8 0.0 1.4 1 0 0 1 1 1 0 Rad51 PEP_mutase PF13714.6 KXH30454.1 - 1.4e-49 168.7 1.4 1.7e-49 168.5 1.4 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 KXH30454.1 - 5.6e-20 71.3 0.7 7.1e-20 71.0 0.7 1.1 1 0 0 1 1 1 1 Isocitrate lyase family MR_MLE_C PF13378.6 KXH30454.1 - 0.0069 16.0 0.5 0.02 14.5 0.4 1.8 1 1 1 2 2 2 1 Enolase C-terminal domain-like ILVD_EDD PF00920.21 KXH30454.1 - 0.024 13.3 0.1 0.43 9.1 0.0 2.2 2 1 0 2 2 2 0 Dehydratase family S-methyl_trans PF02574.16 KXH30454.1 - 0.1 12.4 0.1 0.16 11.7 0.1 1.4 1 0 0 1 1 1 0 Homocysteine S-methyltransferase 6PGD PF00393.19 KXH30454.1 - 0.16 11.3 0.4 1.2 8.4 0.1 1.9 1 1 0 2 2 2 0 6-phosphogluconate dehydrogenase, C-terminal domain ABATE PF07336.11 KXH30454.1 - 0.7 10.6 5.4 1.1 10.0 3.6 2.0 2 0 0 2 2 2 0 Putative stress-induced transcription regulator ETF PF01012.21 KXH30455.1 - 1.2e-45 155.6 0.8 1.4e-45 155.4 0.8 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ArfGap PF01412.18 KXH30456.1 - 4.6e-32 110.5 0.2 8.1e-32 109.8 0.2 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf RRM_1 PF00076.22 KXH30457.1 - 8.1e-32 108.9 0.0 2.7e-15 56.0 0.0 3.3 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KXH30457.1 - 0.00015 21.8 0.0 0.16 12.1 0.0 2.8 2 1 1 3 3 3 2 RNA recognition motif RRM_5 PF13893.6 KXH30457.1 - 0.00019 21.0 0.0 0.3 10.7 0.0 3.1 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Tristanin_u2 PF16638.5 KXH30457.1 - 0.0048 17.7 5.0 0.0048 17.7 5.0 2.9 2 0 0 2 2 2 1 Unstructured region on methyltransferase between zinc-fingers PHM7_cyt PF14703.6 KXH30457.1 - 0.031 14.5 0.1 12 6.1 0.0 3.2 3 0 0 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter DUF4783 PF16022.5 KXH30457.1 - 0.035 14.3 0.0 0.93 9.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4783) DbpA PF03880.15 KXH30457.1 - 0.051 13.6 0.3 10 6.2 0.0 2.9 3 0 0 3 3 3 0 DbpA RNA binding domain Limkain-b1 PF11608.8 KXH30457.1 - 0.11 12.6 0.2 20 5.3 0.0 2.8 3 0 0 3 3 3 0 Limkain b1 DUF4944 PF16302.5 KXH30457.1 - 0.17 11.9 0.0 19 5.3 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4944) S-methyl_trans PF02574.16 KXH30507.1 - 1.1e-58 199.2 0.0 1.2e-58 199.0 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Hexapep PF00132.24 KXH30509.1 - 2.2e-05 24.0 3.2 0.0058 16.3 0.4 3.4 1 1 3 4 4 4 4 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 KXH30509.1 - 3.8e-05 24.1 0.0 8.4e-05 23.0 0.0 1.6 1 1 0 1 1 1 1 MobA-like NTP transferase domain DUF4954 PF16314.5 KXH30509.1 - 0.00015 20.1 0.2 0.00022 19.6 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) Fucokinase PF07959.12 KXH30509.1 - 0.00095 18.2 0.2 0.0015 17.6 0.2 1.2 1 0 0 1 1 1 1 L-fucokinase NTP_transferase PF00483.23 KXH30509.1 - 0.0046 16.6 0.0 0.0081 15.8 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep_2 PF14602.6 KXH30509.1 - 0.28 11.0 5.3 0.26 11.1 0.2 3.1 3 1 0 3 3 3 0 Hexapeptide repeat of succinyl-transferase MFS_1 PF07690.16 KXH30525.1 - 1.4e-16 60.4 12.3 1.7e-16 60.1 12.3 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Helo_like_N PF17111.5 KXH30526.1 - 0.00038 19.9 0.0 0.00048 19.6 0.0 1.1 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins SesA PF17107.5 KXH30526.1 - 0.065 13.4 0.1 0.11 12.7 0.1 1.4 1 1 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases adh_short PF00106.25 KXH30527.1 - 4.6e-24 85.0 0.0 1.8e-21 76.5 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXH30527.1 - 1.7e-13 50.7 0.0 7.4e-13 48.6 0.0 1.7 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH30527.1 - 8.6e-10 38.8 0.0 1.3e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 KXH30527.1 - 8.4e-05 22.1 0.0 0.00045 19.7 0.1 1.8 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KXH30527.1 - 0.0019 17.7 0.0 0.0047 16.4 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF3425 PF11905.8 KXH30528.1 - 8.3e-18 64.6 0.0 2.2e-17 63.2 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3425) CorA PF01544.18 KXH30529.1 - 1.1e-06 28.2 0.1 6.5e-06 25.7 0.0 2.1 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein DUF755 PF05501.11 KXH30529.1 - 1.8 8.9 12.6 6.1 7.1 12.6 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Tyrosinase PF00264.20 KXH30530.1 - 3e-38 132.4 0.9 4.1e-38 131.9 0.9 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase Tyrosinase PF00264.20 KXH30532.1 - 7.8e-35 121.2 0.0 1.1e-34 120.7 0.0 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase Pyr_redox_3 PF13738.6 KXH30533.1 - 1.2e-17 64.1 0.0 1e-16 61.1 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KXH30533.1 - 2e-16 59.5 0.0 6.9e-16 57.7 0.0 1.7 1 1 1 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KXH30533.1 - 1.2e-12 47.7 0.0 1.9e-10 40.4 0.0 2.4 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KXH30533.1 - 6.1e-12 45.4 0.0 7e-09 35.3 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXH30533.1 - 1.3e-08 35.0 0.1 5.1e-07 29.8 0.1 3.2 2 1 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KXH30533.1 - 2.1e-06 27.9 0.0 4.9e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KXH30533.1 - 9.4e-06 24.6 0.2 0.023 13.4 0.1 2.3 2 0 0 2 2 2 2 HI0933-like protein Thi4 PF01946.17 KXH30533.1 - 1.3e-05 24.5 0.1 3e-05 23.4 0.1 1.6 1 1 0 1 1 1 1 Thi4 family DAO PF01266.24 KXH30533.1 - 2.5e-05 24.0 0.3 0.022 14.3 0.1 2.5 3 0 0 3 3 3 2 FAD dependent oxidoreductase Amino_oxidase PF01593.24 KXH30533.1 - 0.00028 20.3 0.1 0.49 9.6 0.0 3.3 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.19 KXH30533.1 - 0.00094 18.5 0.1 0.056 12.7 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 KXH30533.1 - 0.018 14.1 0.4 0.11 11.5 0.5 2.2 2 1 0 2 2 2 0 Lycopene cyclase protein FAD_oxidored PF12831.7 KXH30533.1 - 0.14 11.5 0.1 0.32 10.3 0.1 1.6 1 1 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KXH30533.1 - 0.3 10.1 0.7 0.9 8.5 0.2 2.0 3 0 0 3 3 3 0 FAD binding domain OTT_1508_deam PF14441.6 KXH30535.1 - 2.3e-18 65.9 0.7 4.7e-18 65.0 0.7 1.5 1 0 0 1 1 1 1 OTT_1508-like deaminase Fez1 PF06818.15 KXH30536.1 - 0.0018 18.8 24.3 0.72 10.3 4.7 4.4 3 1 0 4 4 4 3 Fez1 HMMR_N PF15905.5 KXH30536.1 - 0.0018 17.8 15.5 0.47 9.9 4.5 3.6 3 1 0 3 3 3 3 Hyaluronan mediated motility receptor N-terminal UPF0242 PF06785.11 KXH30536.1 - 0.0026 17.9 17.6 0.59 10.2 1.0 4.8 3 1 2 5 5 5 2 Uncharacterised protein family (UPF0242) N-terminus Spc7 PF08317.11 KXH30536.1 - 0.01 14.7 28.2 0.18 10.6 3.8 4.3 3 1 0 4 4 4 0 Spc7 kinetochore protein FAM76 PF16046.5 KXH30536.1 - 0.012 15.0 11.0 0.32 10.3 0.1 3.6 3 1 1 4 4 4 0 FAM76 protein DUF4407 PF14362.6 KXH30536.1 - 0.031 13.6 23.7 0.35 10.2 3.4 3.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) BLOC1_2 PF10046.9 KXH30536.1 - 0.032 14.5 9.8 0.64 10.3 0.8 4.1 3 2 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 AAA_13 PF13166.6 KXH30536.1 - 0.047 12.3 15.3 1.1 7.8 3.6 3.5 3 1 0 3 3 3 0 AAA domain Fib_alpha PF08702.10 KXH30536.1 - 0.066 13.4 8.3 20 5.3 2.2 4.4 3 1 1 5 5 5 0 Fibrinogen alpha/beta chain family HIP1_clath_bdg PF16515.5 KXH30536.1 - 0.099 13.3 29.7 0.62 10.7 5.2 5.7 3 2 2 5 5 5 0 Clathrin-binding domain of Huntingtin-interacting protein 1 MPS2 PF17060.5 KXH30536.1 - 0.13 11.5 10.1 0.044 13.1 1.0 2.9 3 0 0 3 3 3 0 Monopolar spindle protein 2 XLF PF09302.11 KXH30536.1 - 0.25 11.5 7.3 7.8 6.6 0.4 3.9 3 1 0 3 3 3 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component GAS PF13851.6 KXH30536.1 - 0.3 10.4 24.7 0.62 9.4 5.6 3.9 3 1 2 5 5 5 0 Growth-arrest specific micro-tubule binding ATG16 PF08614.11 KXH30536.1 - 0.54 10.5 0.0 0.54 10.5 0.0 5.5 4 2 1 5 5 5 0 Autophagy protein 16 (ATG16) PKcGMP_CC PF16808.5 KXH30536.1 - 1.4 8.9 25.0 1.1 9.2 0.9 6.4 6 0 0 6 6 6 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF1664 PF07889.12 KXH30536.1 - 1.5 8.9 10.9 9.8 6.2 0.1 4.4 4 1 0 4 4 4 0 Protein of unknown function (DUF1664) TMF_DNA_bd PF12329.8 KXH30536.1 - 1.6 8.8 32.8 0.39 10.7 0.2 6.8 5 2 3 8 8 8 0 TATA element modulatory factor 1 DNA binding CR6_interact PF10147.9 KXH30536.1 - 2.8 7.6 13.8 0.063 13.0 4.6 2.4 2 0 0 2 2 2 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 TACC_C PF05010.14 KXH30536.1 - 3.5 7.4 18.3 0.45 10.3 2.6 3.9 3 1 1 4 4 4 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF2203 PF09969.9 KXH30536.1 - 3.8 8.3 20.7 4.3 8.1 1.5 4.8 4 2 0 4 4 4 0 Uncharacterized conserved protein (DUF2203) GCN5L1 PF06320.13 KXH30536.1 - 7.7 6.7 11.9 21 5.3 1.0 4.1 3 1 2 5 5 5 0 GCN5-like protein 1 (GCN5L1) Sigma_reg_N PF13800.6 KXH30537.1 - 3.3 8.1 4.3 1.5 9.2 1.0 1.9 2 0 0 2 2 2 0 Sigma factor regulator N-terminal ACT_3 PF10000.9 KXH30538.1 - 8.7e-24 83.2 0.2 1.3e-23 82.7 0.2 1.3 1 0 0 1 1 1 1 ACT domain ACT_7 PF13840.6 KXH30538.1 - 2.2e-08 33.7 0.0 3.6e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 ACT domain HET PF06985.11 KXH30539.1 - 6.5e-24 84.9 0.1 1.2e-23 84.1 0.1 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) zf-C2H2_4 PF13894.6 KXH30540.1 - 0.078 13.9 2.4 0.16 12.9 0.3 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger SpoIIM PF01944.17 KXH30541.1 - 0.011 15.7 1.6 0.018 15.1 0.1 1.9 2 0 0 2 2 2 0 Stage II sporulation protein M COPI_assoc PF08507.10 KXH30541.1 - 0.03 14.4 1.0 0.047 13.8 0.0 1.8 2 0 0 2 2 2 0 COPI associated protein Myco_arth_vir_N PF09610.10 KXH30542.1 - 0.39 10.9 1.5 0.95 9.6 1.5 1.7 1 0 0 1 1 1 0 Mycoplasma virulence signal region (Myco_arth_vir_N) FAD_binding_4 PF01565.23 KXH30544.1 - 3.1e-19 69.1 2.5 1.2e-18 67.2 2.5 1.9 1 1 0 1 1 1 1 FAD binding domain BBE PF08031.12 KXH30544.1 - 2.4e-12 46.7 0.1 4.9e-12 45.8 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like Cellulase PF00150.18 KXH30545.1 - 1e-32 113.7 3.3 1.6e-32 113.1 3.3 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_X2 PF03442.14 KXH30545.1 - 1.2e-22 79.8 2.5 1.1e-21 76.7 0.9 2.8 3 0 0 3 3 3 1 Carbohydrate binding domain X2 CBM_1 PF00734.18 KXH30545.1 - 5.1e-12 45.5 14.4 1.3e-11 44.2 14.4 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain SOG2 PF10428.9 KXH30545.1 - 1.3 8.2 8.8 0.054 12.7 1.6 1.9 2 0 0 2 2 2 0 RAM signalling pathway protein Mrx7 PF10906.8 KXH30546.1 - 1.6e-05 25.0 0.0 1.9e-05 24.8 0.0 1.1 1 0 0 1 1 1 1 MIOREX complex component 7 Fungal_trans PF04082.18 KXH30547.1 - 0.024 13.7 0.0 0.043 12.9 0.0 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain ELYS PF13934.6 KXH30548.1 - 6.6e-70 235.5 1.9 7.9e-70 235.3 1.9 1.1 1 0 0 1 1 1 1 Nuclear pore complex assembly SMC_N PF02463.19 KXH30549.1 - 7.6e-73 244.6 21.3 4.5e-72 242.0 21.3 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KXH30549.1 - 1.7e-24 86.4 0.0 7.8e-24 84.2 0.0 2.3 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 KXH30549.1 - 9.7e-13 48.6 1.1 4.5e-05 23.4 0.4 3.6 2 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KXH30549.1 - 0.00054 19.6 0.0 0.0011 18.7 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain Spc7 PF08317.11 KXH30549.1 - 0.0032 16.4 26.3 0.0032 16.4 26.3 7.3 3 2 4 7 7 7 2 Spc7 kinetochore protein CLZ PF16526.5 KXH30549.1 - 0.008 16.5 6.6 0.008 16.5 6.6 7.8 7 2 2 9 9 9 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels AT_hook PF02178.19 KXH30549.1 - 0.24 11.4 4.3 0.95 9.5 4.3 2.2 1 0 0 1 1 1 0 AT hook motif ABC_tran PF00005.27 KXH30549.1 - 1.1 9.8 0.0 1.1 9.8 0.0 6.9 4 2 1 6 6 6 0 ABC transporter NmrA PF05368.13 KXH30551.1 - 3.5e-37 128.2 0.2 4.5e-37 127.8 0.2 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXH30551.1 - 5.5e-15 55.7 0.6 7.2e-15 55.4 0.6 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KXH30551.1 - 0.00013 21.6 0.3 0.00042 19.9 0.3 1.9 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXH30551.1 - 0.0012 17.9 0.0 0.0017 17.4 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 KXH30551.1 - 0.021 14.7 0.4 0.034 14.1 0.4 1.3 1 0 0 1 1 1 0 KR domain NAD_binding_4 PF07993.12 KXH30551.1 - 0.026 13.7 0.2 0.94 8.6 0.1 2.1 2 0 0 2 2 2 0 Male sterility protein DapB_N PF01113.20 KXH30551.1 - 0.09 12.9 0.5 0.37 10.9 0.3 2.0 1 1 1 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Sacchrp_dh_NADP PF03435.18 KXH30551.1 - 0.16 12.2 0.2 0.4 10.9 0.2 1.7 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain DUF3638 PF12340.8 KXH30552.1 - 3.9e-98 327.3 0.1 7.3e-98 326.4 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.8 KXH30552.1 - 4.8e-19 67.4 0.6 9.2e-19 66.5 0.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) adh_short PF00106.25 KXH30554.1 - 6.9e-23 81.1 0.0 2.1e-20 73.0 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXH30554.1 - 6.7e-13 48.7 0.0 1.6e-10 40.9 0.0 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH30554.1 - 3.4e-07 30.4 0.0 1e-06 28.8 0.0 1.6 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KXH30554.1 - 0.022 14.2 0.0 0.029 13.8 0.0 1.1 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KXH30554.1 - 0.085 12.0 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Polysacc_deac_1 PF01522.21 KXH30556.1 - 6.9e-26 90.6 0.0 1e-25 90.1 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 KXH30556.1 - 0.006 15.8 0.0 0.0079 15.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 Corona_NS8 PF12093.8 KXH30556.1 - 0.053 14.1 0.0 0.92 10.1 0.0 2.3 2 0 0 2 2 2 0 Coronavirus NS8 protein DUF1451 PF07295.11 KXH30556.1 - 0.1 12.7 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Zinc-ribbon containing domain GFA PF04828.14 KXH30557.1 - 4.4e-15 55.8 0.7 7.6e-15 55.0 0.7 1.4 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme GLEYA PF10528.9 KXH30558.1 - 3e-09 37.2 0.0 9.9e-09 35.5 0.0 1.8 1 0 0 1 1 1 1 GLEYA domain Collagen_mid PF15984.5 KXH30560.1 - 0.0013 18.6 3.6 0.0013 18.6 3.6 2.1 2 0 0 2 2 2 1 Bacterial collagen, middle region DUF1996 PF09362.10 KXH30561.1 - 1.2e-45 156.4 0.9 1.4e-45 156.1 0.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) zf-C2H2_2 PF12756.7 KXH30562.1 - 2.8e-25 88.6 5.1 5.7e-25 87.6 5.1 1.5 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf_C2H2_ZHX PF18387.1 KXH30562.1 - 2 8.1 0.0 2 8.1 0.0 2.8 3 0 0 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain Cellulase PF00150.18 KXH30563.1 - 4.2e-29 101.8 2.2 4.2e-29 101.8 2.2 1.7 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Sugar_tr PF00083.24 KXH30564.1 - 5.3e-87 292.6 25.4 6.2e-87 292.3 25.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH30564.1 - 6.4e-25 87.8 53.0 2.6e-23 82.5 25.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KXH30564.1 - 1.8e-07 30.0 1.8 1.8e-07 30.0 1.8 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) p450 PF00067.22 KXH30565.1 - 5.8e-66 223.1 0.0 7.4e-66 222.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pectate_lyase PF03211.13 KXH30566.1 - 4.2e-74 248.5 3.4 4.7e-74 248.3 3.4 1.0 1 0 0 1 1 1 1 Pectate lyase Fungal_trans PF04082.18 KXH30567.1 - 1.4e-11 44.0 3.4 4.8e-11 42.2 3.4 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH30567.1 - 1.9e-09 37.5 8.3 3.8e-09 36.5 8.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_3 PF01494.19 KXH30568.1 - 3.3e-69 233.8 0.0 1.5e-38 132.9 0.0 2.1 1 1 1 2 2 2 2 FAD binding domain DAO PF01266.24 KXH30568.1 - 5.7e-05 22.8 0.0 0.00082 19.0 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXH30568.1 - 0.00019 21.6 0.0 0.00045 20.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXH30568.1 - 0.0013 18.1 0.0 0.085 12.1 0.0 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KXH30568.1 - 0.0013 18.2 0.0 0.014 14.7 0.0 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KXH30568.1 - 0.002 18.6 0.0 1.3 9.7 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXH30568.1 - 0.0053 16.0 0.0 0.0095 15.2 0.0 1.3 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 KXH30568.1 - 0.0091 14.7 0.0 0.014 14.1 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 KXH30568.1 - 0.066 12.3 0.0 0.14 11.2 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 KXH30568.1 - 0.099 11.9 0.0 0.22 10.8 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase V_ATPase_I_N PF18670.1 KXH30568.1 - 0.18 12.2 0.0 0.49 10.8 0.0 1.7 2 0 0 2 2 1 0 V-type ATPase subunit I, N-terminal domain GIDA PF01134.22 KXH30568.1 - 0.23 10.5 0.0 3.3 6.7 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A MFS_1 PF07690.16 KXH30570.1 - 3.1e-35 121.7 25.6 3.1e-35 121.7 25.6 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MWFE PF15879.5 KXH30570.1 - 0.095 12.9 0.4 0.095 12.9 0.4 3.2 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase MWFE subunit MFS_1 PF07690.16 KXH30572.1 - 5.1e-20 71.7 25.6 5.1e-20 71.7 25.6 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH30572.1 - 6e-15 55.1 25.3 1.9e-14 53.4 25.3 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter DUF2583 PF10762.9 KXH30572.1 - 0.085 13.3 0.7 0.3 11.5 0.7 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2583) FAD_binding_3 PF01494.19 KXH30574.1 - 3.6e-59 200.8 0.0 3.2e-30 105.6 0.0 2.0 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 KXH30574.1 - 3.5e-05 23.6 0.0 0.00015 21.5 0.0 2.0 2 1 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXH30574.1 - 8.2e-05 22.8 0.0 0.00019 21.6 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KXH30574.1 - 0.00025 20.4 0.0 0.00041 19.7 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 KXH30574.1 - 0.013 14.7 0.0 0.088 12.0 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXH30574.1 - 0.021 14.1 0.2 0.049 12.9 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXH30574.1 - 0.058 12.1 0.0 0.11 11.2 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_2 PF00890.24 KXH30574.1 - 0.11 11.6 0.0 1.1 8.2 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain Glu_dehyd_C PF16912.5 KXH30574.1 - 0.14 11.6 0.0 0.29 10.6 0.0 1.5 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus ABC2_membrane PF01061.24 KXH30575.1 - 5.8e-70 235.0 45.7 1.3e-37 129.3 17.4 2.7 3 0 0 3 3 3 2 ABC-2 type transporter PDR_CDR PF06422.12 KXH30575.1 - 1.5e-31 108.2 0.1 4.4e-27 93.8 0.0 3.1 2 0 0 2 2 2 2 CDR ABC transporter ABC_tran PF00005.27 KXH30575.1 - 2e-31 109.4 0.0 1.1e-15 58.4 0.0 3.1 3 0 0 3 3 3 2 ABC transporter ABC_trans_N PF14510.6 KXH30575.1 - 5.4e-15 55.8 0.1 1.8e-14 54.1 0.1 2.0 1 0 0 1 1 1 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 KXH30575.1 - 1.9e-09 37.1 28.3 2.6e-05 23.5 11.8 2.8 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_33 PF13671.6 KXH30575.1 - 9.6e-08 32.3 0.0 0.0031 17.7 0.0 3.7 3 0 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 KXH30575.1 - 3.3e-07 30.4 0.0 0.00016 21.6 0.0 2.6 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 KXH30575.1 - 3.8e-07 30.6 0.2 0.0015 19.0 0.1 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_18 PF13238.6 KXH30575.1 - 4.7e-06 27.2 0.0 0.00018 22.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KXH30575.1 - 2.4e-05 24.0 0.4 0.0023 17.6 0.3 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_25 PF13481.6 KXH30575.1 - 0.00029 20.5 0.1 0.0041 16.7 0.1 2.3 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 KXH30575.1 - 0.00034 20.1 0.0 0.14 11.6 0.0 2.9 3 1 1 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KXH30575.1 - 0.00066 20.0 0.2 0.11 12.7 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_21 PF13304.6 KXH30575.1 - 0.00096 19.0 0.0 0.33 10.7 0.0 2.7 3 0 0 3 3 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_28 PF13521.6 KXH30575.1 - 0.0013 19.0 0.0 0.44 10.8 0.0 3.0 3 0 0 3 3 3 1 AAA domain cobW PF02492.19 KXH30575.1 - 0.003 17.2 0.2 0.13 11.9 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.6 KXH30575.1 - 0.0037 17.7 0.2 0.12 12.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KXH30575.1 - 0.0046 16.9 1.7 0.36 10.7 0.1 3.1 3 0 0 3 3 2 1 NACHT domain AAA_23 PF13476.6 KXH30575.1 - 0.043 14.3 0.0 0.15 12.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KXH30575.1 - 0.053 14.0 0.0 3.4 8.1 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 KXH30575.1 - 0.055 13.2 0.4 2.2 8.0 0.3 2.4 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KXH30575.1 - 0.12 12.8 0.0 20 5.7 0.0 2.8 2 0 0 2 2 2 0 RNA helicase Viral_helicase1 PF01443.18 KXH30575.1 - 0.15 11.7 0.1 1.5 8.5 0.0 2.5 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase AAA_24 PF13479.6 KXH30575.1 - 0.15 11.7 0.0 12 5.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KXH30575.1 - 0.18 11.9 0.1 8.6 6.5 0.1 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase dNK PF01712.19 KXH30575.1 - 0.19 11.6 0.0 11 5.8 0.0 2.4 2 0 0 2 2 2 0 Deoxynucleoside kinase Methyltransf_2 PF00891.18 KXH30576.1 - 1.7e-14 53.6 0.0 5.4e-14 52.0 0.0 1.8 1 1 0 1 1 1 1 O-methyltransferase domain Methyltransf_23 PF13489.6 KXH30576.1 - 0.0064 16.3 0.0 0.013 15.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH30576.1 - 0.024 15.3 0.0 0.11 13.2 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Trp_DMAT PF11991.8 KXH30577.1 - 5e-73 246.6 0.0 6.2e-73 246.3 0.0 1.0 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase p450 PF00067.22 KXH30578.1 - 5.9e-64 216.5 0.0 8.5e-64 216.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Cyt-b5 PF00173.28 KXH30579.1 - 1.2e-14 54.2 0.0 2.8e-14 53.0 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain IDO PF01231.18 KXH30579.1 - 1.2e-14 54.0 0.0 2.7e-10 39.6 0.0 3.1 2 1 0 2 2 2 2 Indoleamine 2,3-dioxygenase NAD_binding_1 PF00175.21 KXH30579.1 - 0.0016 19.1 0.0 0.0055 17.3 0.0 2.0 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain EspF PF04806.12 KXH30579.1 - 0.54 10.7 2.7 24 5.4 0.1 2.7 2 0 0 2 2 2 0 EspF protein repeat SDH_alpha PF03313.15 KXH30581.1 - 1.4e-99 333.0 0.1 1.8e-99 332.7 0.1 1.2 1 0 0 1 1 1 1 Serine dehydratase alpha chain SDH_beta PF03315.15 KXH30581.1 - 2.6e-54 183.8 0.0 6.5e-54 182.5 0.0 1.7 1 0 0 1 1 1 1 Serine dehydratase beta chain SGL PF08450.12 KXH30582.1 - 2.7e-24 86.1 0.5 5.1e-24 85.2 0.5 1.5 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Str_synth PF03088.16 KXH30582.1 - 9.8e-06 25.6 0.0 6.4e-05 23.0 0.0 2.2 1 1 0 1 1 1 1 Strictosidine synthase Arylesterase PF01731.20 KXH30582.1 - 0.0028 17.8 0.1 0.015 15.5 0.0 2.2 2 0 0 2 2 2 1 Arylesterase LTV PF04180.14 KXH30582.1 - 0.16 11.7 0.0 0.23 11.2 0.0 1.1 1 0 0 1 1 1 0 Low temperature viability protein NHL PF01436.21 KXH30582.1 - 2.1 8.6 4.3 27 5.1 0.0 3.0 3 0 0 3 3 3 0 NHL repeat HSP70 PF00012.20 KXH30591.1 - 4.4e-264 877.2 16.2 5e-264 877.0 16.2 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KXH30591.1 - 8.9e-18 64.2 2.6 2.5e-16 59.4 0.7 2.2 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 KXH30591.1 - 0.00021 21.7 4.0 0.37 11.2 0.1 3.7 3 1 0 3 3 3 2 Cell division protein FtsA DDR PF08841.10 KXH30591.1 - 0.0065 15.5 0.4 0.14 11.1 0.2 2.2 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.18 KXH30591.1 - 0.0069 15.7 2.5 0.15 11.3 0.1 2.9 3 0 0 3 3 3 1 Hydantoinase/oxoprolinase SLC35F PF06027.12 KXH30599.1 - 4.4e-97 325.2 23.2 5.9e-97 324.8 23.2 1.1 1 0 0 1 1 1 1 Solute carrier family 35 CRT-like PF08627.10 KXH30599.1 - 6.3e-10 38.5 6.1 9.7e-10 37.9 6.1 1.3 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 KXH30599.1 - 1.1e-07 32.1 36.9 0.00045 20.4 11.2 2.2 2 0 0 2 2 2 2 EamA-like transporter family FUSC-like PF12805.7 KXH30599.1 - 0.59 9.2 7.5 0.081 12.0 1.9 2.2 2 1 0 2 2 2 0 FUSC-like inner membrane protein yccS DUF3035 PF11233.8 KXH30600.1 - 0.65 10.3 2.2 0.98 9.7 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3035) CFEM PF05730.11 KXH30601.1 - 6.5e-10 39.0 13.8 1.6e-09 37.7 13.8 1.7 1 0 0 1 1 1 1 CFEM domain Macoilin PF09726.9 KXH30601.1 - 7.1 5.1 5.9 8.4 4.8 5.9 1.1 1 0 0 1 1 1 0 Macoilin family DUF3883 PF13020.6 KXH30602.1 - 0.0015 18.5 0.1 0.0038 17.2 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3883) PI3Ka PF00613.20 KXH30604.1 - 1.4e-59 200.6 1.4 2.2e-59 200.0 1.4 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 KXH30604.1 - 4.6e-46 157.7 0.0 1.6e-30 106.8 0.0 2.7 2 1 1 3 3 3 2 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.24 KXH30604.1 - 1.1e-22 80.5 0.2 2.6e-22 79.3 0.0 1.7 2 0 0 2 2 2 1 Phosphoinositide 3-kinase C2 Nse4_C PF08743.10 KXH30605.1 - 1.8e-34 117.8 0.1 3.8e-34 116.8 0.1 1.6 1 0 0 1 1 1 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.6 KXH30605.1 - 4.5e-17 61.9 0.0 4.5e-17 61.9 0.0 2.3 2 0 0 2 2 2 1 Binding domain of Nse4/EID3 to Nse3-MAGE PBP1_TM PF14812.6 KXH30605.1 - 0.11 12.8 8.3 3.7 8.0 4.9 2.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4336 PF14234.6 KXH30606.1 - 4.8e-13 49.0 0.1 3.3e-08 33.1 0.0 2.5 2 1 0 2 2 2 2 Domain of unknown function (DUF4336) BTB PF00651.31 KXH30607.1 - 1.3e-17 64.0 0.1 1.9e-17 63.5 0.1 1.2 1 0 0 1 1 1 1 BTB/POZ domain CNH PF00780.22 KXH30608.1 - 1.1e-79 268.0 0.0 4e-79 266.1 0.0 1.8 2 0 0 2 2 2 1 CNH domain PH_5 PF15405.6 KXH30608.1 - 7e-45 152.5 0.0 1.5e-44 151.4 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.20 KXH30608.1 - 1.2e-35 123.4 0.0 2.4e-35 122.4 0.0 1.5 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.21 KXH30608.1 - 5.5e-15 55.2 0.0 1.2e-14 54.1 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) ATP-synt_C PF00137.21 KXH30609.1 - 1.8e-20 73.0 38.4 3.4e-18 65.7 9.5 3.1 2 1 0 2 2 2 2 ATP synthase subunit C Herpes_UL32 PF06070.11 KXH30610.1 - 1 7.0 5.9 0.12 10.2 1.7 1.5 2 0 0 2 2 2 0 Herpesvirus large structural phosphoprotein UL32 MFS_1 PF07690.16 KXH30611.1 - 7.3e-38 130.4 64.7 9.5e-35 120.1 49.6 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KXH30611.1 - 0.00079 18.4 14.4 0.00079 18.4 14.4 2.5 2 1 1 3 3 3 2 MFS_1 like family DUF3272 PF11676.8 KXH30611.1 - 0.078 13.2 1.7 0.39 11.0 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3272) CD225 PF04505.12 KXH30611.1 - 0.57 10.4 9.9 0.2 11.8 2.0 3.5 2 0 0 2 2 2 0 Interferon-induced transmembrane protein UPF0715 PF17094.5 KXH30611.1 - 10 6.8 12.6 0.48 11.0 4.8 2.8 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0715) PI3_PI4_kinase PF00454.27 KXH30612.1 - 3.4e-52 177.8 0.0 8.5e-52 176.4 0.0 1.8 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase UME PF08064.13 KXH30612.1 - 9.5e-33 112.2 0.7 3.5e-32 110.4 0.0 2.5 2 0 0 2 2 2 1 UME (NUC010) domain FAT PF02259.23 KXH30612.1 - 2.2e-30 106.1 2.0 3.6e-30 105.4 2.0 1.3 1 0 0 1 1 1 1 FAT domain zf-PARP PF00645.18 KXH30612.1 - 4.5e-17 62.7 0.8 1.2e-16 61.4 0.8 1.8 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region FATC PF02260.20 KXH30612.1 - 5.7e-17 61.2 0.5 2.3e-15 56.1 0.0 2.5 2 0 0 2 2 2 1 FATC domain TPR_19 PF14559.6 KXH30612.1 - 0.00036 21.0 1.9 0.041 14.4 0.0 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF4734 PF15881.5 KXH30613.1 - 0.28 11.4 2.3 0.62 10.3 2.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4734) SKG6 PF08693.10 KXH30614.1 - 0.25 10.8 4.5 0.82 9.1 4.5 1.9 1 0 0 1 1 1 0 Transmembrane alpha-helix domain PFK PF00365.20 KXH30615.1 - 1.7e-188 624.8 0.3 1.3e-105 352.8 1.0 2.1 2 0 0 2 2 2 2 Phosphofructokinase UVR PF02151.19 KXH30615.1 - 0.072 12.9 0.2 0.17 11.7 0.2 1.6 1 0 0 1 1 1 0 UvrB/uvrC motif TgMIC1 PF11476.8 KXH30615.1 - 0.085 12.6 0.8 5.4 6.8 0.0 2.4 2 0 0 2 2 2 0 Toxoplasma gondii micronemal protein 1 TgMIC1 DUF211 PF02680.14 KXH30615.1 - 0.11 12.7 0.0 0.26 11.5 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized ArCR, COG1888 Med17 PF10156.9 KXH30616.1 - 3.8e-71 240.2 0.6 2.3e-34 118.9 3.4 2.1 1 1 1 2 2 2 2 Subunit 17 of Mediator complex SLX9 PF15341.6 KXH30616.1 - 0.53 10.7 3.9 1.2 9.6 3.9 1.6 1 1 0 1 1 1 0 Ribosome biogenesis protein SLX9 SNF2_N PF00176.23 KXH30617.1 - 2.5e-61 207.3 0.7 6.6e-61 206.0 0.7 1.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KXH30617.1 - 7.3e-15 55.3 0.0 1.9e-14 53.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.25 KXH30617.1 - 9.6e-08 31.8 5.1 1.9e-07 30.8 5.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.15 KXH30617.1 - 1e-07 32.1 0.1 3.5e-07 30.4 0.0 2.0 2 0 0 2 2 1 1 Type III restriction enzyme, res subunit zf-RING_UBOX PF13445.6 KXH30617.1 - 2.5e-07 30.6 4.2 5.8e-07 29.4 4.2 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KXH30617.1 - 8.1e-07 28.8 2.3 8.1e-07 28.8 2.3 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXH30617.1 - 1.1e-05 25.7 5.2 2.7e-05 24.4 5.2 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KXH30617.1 - 8.2e-05 22.4 4.5 0.00018 21.3 4.5 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.29 KXH30617.1 - 9.9e-05 22.2 3.4 0.00014 21.6 0.7 2.5 2 1 0 2 2 2 1 DEAD/DEAH box helicase zf-C3HC4_4 PF15227.6 KXH30617.1 - 0.00021 21.4 5.0 0.00046 20.3 5.0 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 KXH30617.1 - 0.00045 20.1 4.1 0.00087 19.2 4.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain ERCC3_RAD25_C PF16203.5 KXH30617.1 - 0.037 13.2 0.7 0.074 12.2 0.0 1.9 2 0 0 2 2 2 0 ERCC3/RAD25/XPB C-terminal helicase U-box PF04564.15 KXH30617.1 - 0.14 12.4 0.0 1.9 8.7 0.0 2.7 2 0 0 2 2 2 0 U-box domain zf-WRNIP1_ubi PF18279.1 KXH30617.1 - 0.16 12.6 2.5 2.3 9.0 0.5 2.8 2 0 0 2 2 2 0 Werner helicase-interacting protein 1 ubiquitin-binding domain Hid1 PF12722.7 KXH30617.1 - 0.37 8.9 4.5 0.8 7.8 4.5 1.4 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein zf-RING_10 PF16685.5 KXH30617.1 - 0.43 10.7 2.3 1.2 9.4 2.3 1.7 1 0 0 1 1 1 0 zinc RING finger of MSL2 Prok-RING_4 PF14447.6 KXH30617.1 - 4.3 7.3 6.5 32 4.5 6.9 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 G-gamma PF00631.22 KXH30636.1 - 4.8e-25 87.3 0.0 8.7e-25 86.5 0.0 1.4 1 0 0 1 1 1 1 GGL domain Hamartin PF04388.12 KXH30636.1 - 0.26 9.9 14.5 0.28 9.8 14.5 1.0 1 0 0 1 1 1 0 Hamartin protein Dicty_REP PF05086.12 KXH30636.1 - 0.38 8.7 7.1 0.46 8.4 7.1 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Peptidase_S64 PF08192.11 KXH30636.1 - 8.1 4.8 8.6 9.8 4.5 8.6 1.1 1 0 0 1 1 1 0 Peptidase family S64 PCI PF01399.27 KXH30637.1 - 2.7e-08 34.2 0.5 1.6e-07 31.8 0.0 2.5 2 0 0 2 2 2 1 PCI domain STAS PF01740.21 KXH30637.1 - 0.095 12.3 0.0 0.24 11.0 0.0 1.6 1 0 0 1 1 1 0 STAS domain WSC PF01822.19 KXH30639.1 - 3e-33 113.9 35.0 2.7e-18 65.9 13.1 5.4 5 1 1 6 6 6 2 WSC domain Stm1_N PF09598.10 KXH30640.1 - 7e-14 52.4 2.9 7e-14 52.4 2.9 4.0 4 1 0 4 4 4 1 Stm1 MFS_1 PF07690.16 KXH30642.1 - 3.6e-21 75.5 31.5 7.4e-11 41.6 9.0 3.1 3 0 0 3 3 3 3 Major Facilitator Superfamily ATG22 PF11700.8 KXH30642.1 - 2.4e-08 33.0 1.6 3.7e-07 29.2 0.0 3.0 3 1 1 4 4 4 2 Vacuole effluxer Atg22 like DUF4022 PF13214.6 KXH30642.1 - 0.014 15.6 2.4 0.073 13.3 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4022) LacY_symp PF01306.19 KXH30642.1 - 2.2 7.0 11.5 0.1 11.4 5.1 1.9 2 0 0 2 2 2 0 LacY proton/sugar symporter Sugar_tr PF00083.24 KXH30642.1 - 9.9 4.9 15.6 0.029 13.2 1.5 3.1 4 0 0 4 4 4 0 Sugar (and other) transporter Actin PF00022.19 KXH30643.1 - 5.3e-28 97.8 0.0 1.4e-18 66.7 0.0 2.6 2 1 0 2 2 2 2 Actin Actin_micro PF17003.5 KXH30643.1 - 0.00042 19.6 0.7 0.22 10.6 0.3 2.2 2 0 0 2 2 2 2 Putative actin-like family FtsA PF14450.6 KXH30643.1 - 0.026 14.9 0.0 0.072 13.5 0.0 1.9 1 1 0 1 1 1 0 Cell division protein FtsA MreB_Mbl PF06723.13 KXH30643.1 - 0.072 11.9 0.0 0.2 10.4 0.0 1.6 2 0 0 2 2 2 0 MreB/Mbl protein Forkhead PF00250.18 KXH30649.1 - 1.6e-17 63.5 0.0 2.8e-17 62.8 0.0 1.4 1 0 0 1 1 1 1 Forkhead domain Cu-oxidase_3 PF07732.15 KXH30662.1 - 3.4e-39 133.5 3.9 3.4e-39 133.5 3.9 2.7 3 1 1 4 4 4 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KXH30662.1 - 1.3e-36 125.3 1.3 1.3e-36 125.3 1.3 3.0 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.22 KXH30662.1 - 1.5e-34 119.4 0.6 3.6e-34 118.2 0.1 2.0 2 0 0 2 2 2 1 Multicopper oxidase MFS_1 PF07690.16 KXH30663.1 - 6.9e-37 127.2 22.9 6.9e-37 127.2 22.9 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH30663.1 - 8.9e-15 54.5 13.2 1.2e-14 54.1 13.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter ALMT PF11744.8 KXH30663.1 - 0.23 10.3 2.1 0.33 9.7 2.1 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF3938 PF13074.6 KXH30663.1 - 0.97 9.7 0.0 0.97 9.7 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3938) Trp_oprn_chp PF09534.10 KXH30663.1 - 1.2 8.9 11.3 0.1 12.4 1.7 2.9 3 0 0 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) G_glu_transpept PF01019.21 KXH30664.1 - 7.3e-145 483.6 0.0 8.6e-145 483.4 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Glutaredoxin PF00462.24 KXH30665.1 - 1.3e-15 57.4 0.0 2.3e-15 56.5 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin Flavoprotein PF02441.19 KXH30666.1 - 5.2e-48 162.8 0.1 6.1e-48 162.6 0.1 1.0 1 0 0 1 1 1 1 Flavoprotein Mpp10 PF04006.12 KXH30667.1 - 8.3e-111 371.3 72.8 2e-109 366.8 72.8 2.2 1 1 0 1 1 1 1 Mpp10 protein CIAPIN1 PF05093.13 KXH30668.1 - 1.9e-41 140.6 2.2 2.9e-41 140.0 2.2 1.3 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DRE2_N PF16803.5 KXH30668.1 - 3.9e-34 117.7 0.0 5.7e-34 117.2 0.0 1.2 1 0 0 1 1 1 1 Fe-S cluster assembly protein DRE2 N-terminus Peptidase_S10 PF00450.22 KXH30669.1 - 2.3e-113 379.8 0.1 2.7e-113 379.5 0.1 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase RNA_Me_trans PF04252.13 KXH30670.1 - 2e-82 275.7 0.0 2.2e-82 275.5 0.0 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase Glyco_hydro_127 PF07944.12 KXH30671.1 - 1.6e-100 337.1 0.0 2.1e-100 336.7 0.0 1.1 1 0 0 1 1 1 1 Beta-L-arabinofuranosidase, GH127 zf-CCCH_4 PF18044.1 KXH30672.1 - 9e-07 28.6 2.1 1.4e-06 27.9 2.1 1.3 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KXH30672.1 - 6.2e-06 26.1 5.5 1.2e-05 25.2 5.5 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 KXH30672.1 - 8.5e-05 22.4 2.8 0.00016 21.5 2.8 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 KXH30672.1 - 0.0063 16.7 0.2 0.016 15.4 0.2 1.7 1 0 0 1 1 1 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 KXH30672.1 - 0.034 14.6 1.8 0.054 14.0 1.8 1.3 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger Torus PF16131.5 KXH30672.1 - 0.16 12.7 0.1 0.16 12.7 0.1 3.0 3 0 0 3 3 3 0 Torus domain Sec1 PF00995.23 KXH30673.1 - 1.4e-126 424.0 0.0 1.6e-126 423.8 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Chitin_synth_1 PF01644.17 KXH30674.1 - 2e-74 249.0 0.2 3.2e-74 248.3 0.2 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 KXH30674.1 - 3.3e-28 97.4 0.0 6.5e-28 96.5 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 KXH30674.1 - 1.3e-22 80.1 3.5 2.1e-17 62.9 0.0 2.5 3 0 0 3 3 3 2 Chitin synthase Glyco_trans_2_3 PF13632.6 KXH30674.1 - 7.3e-06 26.0 7.1 7.3e-06 26.0 7.1 2.6 2 1 0 2 2 2 1 Glycosyl transferase family group 2 PC4 PF02229.16 KXH30675.1 - 9.2e-24 82.8 0.5 1.4e-23 82.2 0.1 1.5 2 0 0 2 2 2 1 Transcriptional Coactivator p15 (PC4) YqfQ PF14181.6 KXH30675.1 - 0.076 13.2 0.4 0.076 13.2 0.4 2.0 2 0 0 2 2 2 0 YqfQ-like protein PXA PF02194.15 KXH30676.1 - 5.2e-34 117.8 0.6 1.2e-33 116.6 0.1 1.9 2 0 0 2 2 2 1 PXA domain Nexin_C PF08628.12 KXH30676.1 - 4.4e-24 85.2 0.1 1.5e-23 83.5 0.1 2.0 1 0 0 1 1 1 1 Sorting nexin C terminal PX PF00787.24 KXH30676.1 - 7e-07 29.2 0.1 4.7e-06 26.6 0.0 2.3 2 0 0 2 2 2 1 PX domain FliJ PF02050.16 KXH30676.1 - 0.018 15.2 1.4 0.044 14.0 1.4 1.6 1 0 0 1 1 1 0 Flagellar FliJ protein Macoilin PF09726.9 KXH30676.1 - 0.29 9.6 9.8 0.46 9.0 9.8 1.2 1 0 0 1 1 1 0 Macoilin family Hydantoinase_B PF02538.14 KXH30677.1 - 1.4e-220 733.1 0.1 2e-220 732.6 0.1 1.2 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 KXH30677.1 - 6.9e-104 347.2 1.0 1.4e-103 346.2 1.0 1.6 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 KXH30677.1 - 2.6e-61 206.4 1.9 1e-59 201.2 0.1 2.6 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region Ran_BP1 PF00638.18 KXH30680.1 - 4.2e-12 46.4 0.0 2.3e-11 44.0 0.0 2.1 1 1 0 1 1 1 1 RanBP1 domain Nucleoporin_FG PF13634.6 KXH30680.1 - 1.3e-05 25.9 37.6 6.9e-05 23.6 16.4 10.1 2 1 8 10 10 10 7 Nucleoporin FG repeat region SCP2 PF02036.17 KXH30681.1 - 1.5e-25 89.6 0.3 1.7e-25 89.4 0.3 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 KXH30681.1 - 3.3e-06 27.4 0.1 3.8e-06 27.2 0.1 1.1 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal SCP2_2 PF13530.6 KXH30681.1 - 0.024 15.0 0.0 0.029 14.8 0.0 1.2 1 0 0 1 1 1 0 Sterol carrier protein domain Pectate_lyase_3 PF12708.7 KXH30682.1 - 3e-47 161.2 17.4 6.2e-45 153.7 3.4 3.3 3 1 1 4 4 4 2 Pectate lyase superfamily protein Toxin_18 PF08087.11 KXH30682.1 - 0.26 11.3 2.7 2.6 8.1 0.3 2.8 2 0 0 2 2 2 0 Conotoxin O-superfamily Adeno_E1B_55K PF01696.17 KXH30682.1 - 5.6 5.5 6.4 2.3 6.8 3.5 1.7 2 0 0 2 2 2 0 Adenovirus EB1 55K protein / large t-antigen Pentapeptide PF00805.22 KXH30682.1 - 6.1 6.6 6.0 28 4.5 0.0 4.3 6 0 0 6 6 6 0 Pentapeptide repeats (8 copies) LETM1 PF07766.13 KXH30683.1 - 4.9e-08 32.7 0.2 1.2e-07 31.3 0.1 1.6 2 0 0 2 2 2 1 LETM1-like protein DLH PF01738.18 KXH30684.1 - 2.4e-16 59.9 0.0 3.3e-13 49.7 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family BAAT_C PF08840.11 KXH30684.1 - 0.013 15.4 0.0 1.5 8.7 0.0 2.2 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_3 PF07859.13 KXH30684.1 - 0.063 13.1 0.2 0.43 10.4 0.0 2.3 2 1 0 2 2 2 0 alpha/beta hydrolase fold GAF_2 PF13185.6 KXH30685.1 - 1.1e-09 38.7 0.0 1.6e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 KXH30685.1 - 6.9e-05 23.5 0.0 8.7e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 GAF domain Spermine_synth PF01564.17 KXH30686.1 - 6.8e-74 247.4 0.0 1.9e-73 245.9 0.0 1.7 1 1 1 2 2 2 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 KXH30686.1 - 2e-20 72.4 0.1 3.3e-20 71.7 0.1 1.4 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 KXH30686.1 - 0.00028 21.5 0.0 0.0006 20.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH30686.1 - 0.0039 17.9 0.3 0.032 15.0 0.0 2.4 3 0 0 3 3 3 1 Methyltransferase domain DUF43 PF01861.16 KXH30686.1 - 0.012 14.8 0.0 0.019 14.2 0.0 1.2 1 0 0 1 1 1 0 Branched-chain polyamine synthase A C-terminal domain Methyltransf_18 PF12847.7 KXH30686.1 - 0.045 13.7 0.0 0.086 12.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain G-alpha PF00503.20 KXH30687.1 - 9.5e-25 87.5 0.1 1.1e-24 87.3 0.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KXH30687.1 - 0.0014 18.1 0.0 0.0016 17.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_29 PF13555.6 KXH30687.1 - 0.023 14.4 0.0 0.037 13.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.6 KXH30687.1 - 0.026 14.1 0.0 0.026 14.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 KXH30687.1 - 0.036 13.4 0.0 0.048 13.0 0.0 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family DAP3 PF10236.9 KXH30687.1 - 0.058 12.6 0.1 0.068 12.3 0.1 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 DUF2999 PF11212.8 KXH30687.1 - 0.12 12.7 0.0 0.17 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2999) G-alpha PF00503.20 KXH30688.1 - 9.6e-83 278.3 0.1 1.1e-82 278.0 0.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KXH30688.1 - 6.1e-09 35.6 0.1 1.3e-08 34.5 0.1 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family CN_hydrolase PF00795.22 KXH30689.1 - 1.2e-54 185.4 0.0 1.4e-54 185.2 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase FAD_binding_4 PF01565.23 KXH30690.1 - 1.1e-22 80.2 0.6 1.1e-22 80.2 0.6 1.8 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 KXH30690.1 - 3.4e-09 36.7 0.0 7.3e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like BTB PF00651.31 KXH30690.1 - 0.00023 21.3 0.0 0.00046 20.4 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Pup_ligase PF03136.15 KXH30690.1 - 0.14 11.2 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 Pup-ligase protein p450 PF00067.22 KXH30691.1 - 1.2e-40 139.6 0.0 2.2e-40 138.8 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 DUF2417 PF10329.9 KXH30691.1 - 0.22 10.9 0.7 0.59 9.5 0.1 2.0 2 0 0 2 2 2 0 Region of unknown function (DUF2417) Thioesterase PF00975.20 KXH30692.1 - 9.4e-24 84.8 0.0 2.2e-23 83.6 0.0 1.6 2 0 0 2 2 2 1 Thioesterase domain Abhydrolase_6 PF12697.7 KXH30692.1 - 8.4e-07 29.8 0.0 1.2e-06 29.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXH30692.1 - 1.3e-05 25.0 0.0 5.5e-05 22.9 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXH30692.1 - 8.7e-05 21.9 0.0 0.00015 21.2 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF2974 PF11187.8 KXH30692.1 - 0.00022 20.9 0.0 0.00034 20.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_3 PF07859.13 KXH30692.1 - 0.0058 16.5 0.0 0.0092 15.9 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 KXH30692.1 - 0.026 14.3 0.0 0.044 13.5 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.13 KXH30692.1 - 0.14 11.8 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_2 PF02230.16 KXH30692.1 - 0.16 11.7 0.0 0.42 10.4 0.0 1.6 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Cwf_Cwc_15 PF04889.12 KXH30692.1 - 0.85 9.3 5.4 1.3 8.7 5.4 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Asp PF00026.23 KXH30693.1 - 3.6e-09 36.5 0.0 2e-08 34.0 0.0 2.1 1 1 0 1 1 1 1 Eukaryotic aspartyl protease DUF4384 PF14326.6 KXH30693.1 - 0.12 12.5 0.0 0.29 11.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4384) FAD_binding_3 PF01494.19 KXH30694.1 - 2.7e-31 109.1 0.0 2.8e-17 63.0 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KXH30694.1 - 1.9e-05 24.8 0.5 5.4e-05 23.3 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 KXH30694.1 - 4.1e-05 22.6 2.3 0.12 11.2 0.0 2.3 1 1 0 2 2 2 2 Tryptophan halogenase Lycopene_cycl PF05834.12 KXH30694.1 - 7.1e-05 22.0 0.7 0.00024 20.3 0.7 1.7 1 1 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KXH30694.1 - 0.00042 19.6 1.0 0.17 11.1 0.0 2.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXH30694.1 - 0.0008 19.9 0.4 0.0067 17.0 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXH30694.1 - 0.0021 17.4 0.1 0.033 13.4 0.2 2.3 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 KXH30694.1 - 0.077 12.1 0.1 0.13 11.4 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain SE PF08491.10 KXH30694.1 - 0.2 10.7 0.0 0.75 8.8 0.0 1.7 2 0 0 2 2 2 0 Squalene epoxidase DAO PF01266.24 KXH30694.1 - 0.38 10.3 2.3 0.52 9.8 1.2 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase Zn_clus PF00172.18 KXH30695.1 - 1.3e-05 25.2 11.7 2.1e-05 24.5 11.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tmemb_cc2 PF10267.9 KXH30695.1 - 0.073 12.2 2.6 0.12 11.5 2.6 1.3 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein ketoacyl-synt PF00109.26 KXH30697.1 - 4.6e-74 249.2 0.0 1.1e-73 248.0 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain AMP-binding PF00501.28 KXH30697.1 - 1.2e-73 248.2 0.0 2e-73 247.4 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 KXH30697.1 - 1e-66 225.5 0.0 1.5e-66 225.0 0.0 1.2 1 0 0 1 1 1 1 Condensation domain KR PF08659.10 KXH30697.1 - 1.4e-58 197.7 8.6 1.6e-57 194.3 0.4 4.1 4 0 0 4 4 4 1 KR domain PS-DH PF14765.6 KXH30697.1 - 3.3e-58 197.3 0.0 6.3e-58 196.4 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 KXH30697.1 - 5.8e-57 193.6 0.0 1e-56 192.8 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KXH30697.1 - 1e-39 135.2 0.0 9.1e-39 132.1 0.0 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.12 KXH30697.1 - 6.5e-38 130.4 0.0 1.5e-37 129.2 0.0 1.6 1 0 0 1 1 1 1 Male sterility protein KAsynt_C_assoc PF16197.5 KXH30697.1 - 7.5e-21 74.7 0.0 1.7e-20 73.6 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension PP-binding PF00550.25 KXH30697.1 - 1.9e-15 56.9 0.0 3.4e-06 27.3 0.0 3.0 2 0 0 2 2 2 2 Phosphopantetheine attachment site ADH_zinc_N PF00107.26 KXH30697.1 - 1.2e-14 54.4 1.3 3.5e-14 52.9 0.2 2.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXH30697.1 - 2.5e-13 51.2 0.0 1.1e-12 49.1 0.0 2.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 KXH30697.1 - 3.1e-10 39.8 4.1 1.7e-09 37.4 0.4 2.8 2 0 0 2 2 2 1 short chain dehydrogenase ADH_N PF08240.12 KXH30697.1 - 1.1e-05 25.2 0.1 3.1e-05 23.8 0.0 1.7 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain adh_short_C2 PF13561.6 KXH30697.1 - 0.0017 18.0 3.3 0.0017 17.9 0.4 2.3 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase AMP-binding_C PF13193.6 KXH30697.1 - 0.0018 19.2 0.0 0.0055 17.6 0.0 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain 3Beta_HSD PF01073.19 KXH30697.1 - 0.0035 16.4 0.0 0.13 11.2 0.0 2.5 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Thiolase_N PF00108.23 KXH30697.1 - 0.026 13.9 0.0 0.097 12.0 0.0 1.9 1 0 0 1 1 1 0 Thiolase, N-terminal domain SAT PF16073.5 KXH30697.1 - 0.029 14.1 0.3 0.69 9.6 0.3 2.6 1 1 0 1 1 1 0 Starter unit:ACP transacylase in aflatoxin biosynthesis Alpha_GJ PF03229.13 KXH30697.1 - 5.1 7.7 7.6 6.6 7.3 4.2 2.7 2 0 0 2 2 2 0 Alphavirus glycoprotein J DUF2462 PF09495.10 KXH30698.1 - 3e-16 59.9 11.5 3e-16 59.9 11.5 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF2462) A_deaminase PF00962.22 KXH30699.1 - 2.5e-23 82.9 0.0 4.2e-23 82.2 0.0 1.4 1 0 0 1 1 1 1 Adenosine/AMP deaminase NmrA PF05368.13 KXH30700.1 - 4.1e-08 33.1 0.0 1.3e-06 28.2 0.0 2.1 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.6 KXH30700.1 - 8.4e-07 29.1 0.1 5.9e-06 26.3 0.1 2.2 1 1 0 1 1 1 1 NAD(P)H-binding NAD_binding_7 PF13241.6 KXH30700.1 - 0.00034 21.0 0.0 0.00061 20.2 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding Sacchrp_dh_NADP PF03435.18 KXH30700.1 - 0.00037 20.7 0.0 0.00061 20.1 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 KXH30700.1 - 0.0082 16.4 0.1 0.013 15.7 0.1 1.3 1 0 0 1 1 1 1 TrkA-N domain Shikimate_DH PF01488.20 KXH30700.1 - 0.012 15.7 0.1 0.02 15.0 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 KXH30700.1 - 0.099 13.2 0.1 0.23 12.1 0.1 1.7 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 KXH30700.1 - 0.18 11.4 0.1 0.54 9.9 0.1 1.9 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Ribosomal_L22e PF01776.17 KXH30701.1 - 5.3e-46 155.5 1.7 6.8e-46 155.1 1.7 1.1 1 0 0 1 1 1 1 Ribosomal L22e protein family DUF3568 PF12092.8 KXH30701.1 - 0.086 12.9 1.1 0.11 12.5 0.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3568) Mito_carr PF00153.27 KXH30702.1 - 2.8e-53 177.8 0.4 2.1e-17 62.8 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF92 PF01940.16 KXH30703.1 - 6.9e-90 300.6 2.3 9.5e-90 300.1 2.3 1.2 1 0 0 1 1 1 1 Integral membrane protein DUF92 Pyridoxal_deC PF00282.19 KXH30704.1 - 1.4e-26 93.1 0.0 1.8e-26 92.8 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain ArfGap PF01412.18 KXH30705.1 - 3.9e-38 130.1 0.2 3.9e-38 130.1 0.2 1.9 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf UBA PF00627.31 KXH30705.1 - 0.16 12.0 0.0 0.39 10.7 0.0 1.7 1 0 0 1 1 1 0 UBA/TS-N domain Oxysterol_BP PF01237.18 KXH30706.1 - 1e-109 366.9 0.0 2.2e-109 365.7 0.0 1.6 1 1 0 1 1 1 1 Oxysterol-binding protein PH_8 PF15409.6 KXH30706.1 - 8.1e-39 131.8 1.1 4.5e-38 129.4 0.2 2.4 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 KXH30706.1 - 8.5e-08 32.7 0.0 2.3e-07 31.2 0.0 1.8 1 0 0 1 1 1 1 PH domain PH_17 PF18012.1 KXH30706.1 - 0.17 11.6 0.3 0.75 9.6 0.3 2.1 2 0 0 2 2 2 0 PH domain Ribosomal_L27e PF01777.18 KXH30706.1 - 0.24 11.8 0.8 16 6.0 0.0 2.6 2 0 0 2 2 2 0 Ribosomal L27e protein family HEPN_SAV_6107 PF18726.1 KXH30706.1 - 0.54 10.8 5.1 0.26 11.8 0.6 2.7 2 0 0 2 2 2 0 SAV_6107-like HEPN Cu-oxidase_3 PF07732.15 KXH30707.1 - 1e-44 151.3 8.5 1.4e-39 134.8 1.9 4.2 4 0 0 4 4 4 3 Multicopper oxidase Cu-oxidase_2 PF07731.14 KXH30707.1 - 1.6e-40 138.0 13.3 2.9e-37 127.5 2.4 3.8 3 1 0 3 3 3 3 Multicopper oxidase Cu-oxidase PF00394.22 KXH30707.1 - 2.7e-25 89.3 2.6 4.3e-23 82.2 0.0 3.0 3 1 0 3 3 3 2 Multicopper oxidase bZIP_2 PF07716.15 KXH30716.1 - 0.00085 19.4 14.2 0.0014 18.6 14.2 1.4 1 0 0 1 1 1 1 Basic region leucine zipper DivIC PF04977.15 KXH30716.1 - 1.2 9.0 7.2 0.31 10.8 4.0 1.6 1 1 1 2 2 2 0 Septum formation initiator bZIP_1 PF00170.21 KXH30716.1 - 3.4 7.9 12.7 7.7 6.7 12.7 1.6 1 1 0 1 1 1 0 bZIP transcription factor TctB PF07331.11 KXH30717.1 - 0.011 16.0 4.5 0.18 12.1 0.1 2.3 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family DUF3176 PF11374.8 KXH30717.1 - 0.036 14.3 2.7 0.046 13.9 1.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3176) Trp_oprn_chp PF09534.10 KXH30717.1 - 0.66 9.7 3.8 0.82 9.4 2.3 1.8 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Metallophos PF00149.28 KXH30718.1 - 3.3e-10 40.8 0.1 5e-10 40.2 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KXH30718.1 - 6.4e-08 33.0 0.0 8.6e-06 26.0 0.0 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain W2 PF02020.18 KXH30719.1 - 2.9e-22 78.6 2.4 5.9e-22 77.6 2.4 1.6 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.24 KXH30719.1 - 6.1e-08 32.1 7.9 4.4e-05 23.0 3.2 3.6 1 1 1 2 2 2 2 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.23 KXH30719.1 - 0.00055 19.6 0.0 0.00097 18.8 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase DUF4954 PF16314.5 KXH30719.1 - 0.00098 17.4 0.3 0.0017 16.6 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) Fucokinase PF07959.12 KXH30719.1 - 0.0044 16.0 1.1 0.33 9.8 0.2 2.1 1 1 1 2 2 2 2 L-fucokinase NTP_transf_3 PF12804.7 KXH30719.1 - 0.0075 16.6 0.0 0.024 15.0 0.0 1.8 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 KXH30719.1 - 0.045 13.5 7.6 0.31 10.8 1.6 3.5 1 1 2 3 3 3 0 Hexapeptide repeat of succinyl-transferase HAD_SAK_1 PF10307.9 KXH30720.1 - 7.9e-80 267.4 0.0 1.1e-79 267.0 0.0 1.2 1 0 0 1 1 1 1 HAD domain family 1 in Swiss Army Knife RNA repair proteins Abhydrolase_3 PF07859.13 KXH30723.1 - 2.4e-45 155.0 0.0 3.1e-45 154.6 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KXH30723.1 - 0.00053 19.0 0.4 0.0011 17.9 0.4 1.4 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 KXH30723.1 - 0.023 14.1 0.2 0.17 11.4 0.4 2.1 3 0 0 3 3 3 0 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KXH30723.1 - 0.03 13.6 0.2 0.12 11.7 0.2 1.8 1 1 0 1 1 1 0 Serine aminopeptidase, S33 Say1_Mug180 PF10340.9 KXH30723.1 - 0.25 10.2 0.9 0.64 8.8 0.9 1.7 1 1 0 1 1 1 0 Steryl acetyl hydrolase AXE1 PF05448.12 KXH30723.1 - 0.25 10.0 0.0 0.37 9.4 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Lipase_GDSL_2 PF13472.6 KXH30724.1 - 1.4e-12 48.4 0.2 1.9e-12 48.0 0.2 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KXH30724.1 - 2.6e-06 27.5 0.0 3.7e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase ALGX PF16822.5 KXH30724.1 - 0.022 14.4 1.0 0.084 12.5 0.6 1.9 2 0 0 2 2 2 0 SGNH hydrolase-like domain, acetyltransferase AlgX PaRep2a PF07903.11 KXH30724.1 - 0.15 11.9 0.1 0.39 10.6 0.0 1.7 2 0 0 2 2 2 0 PaRep2a protein Virul_fac_BrkB PF03631.15 KXH30725.1 - 0.0027 17.4 2.9 0.0035 17.0 2.9 1.1 1 0 0 1 1 1 1 Virulence factor BrkB PHO4 PF01384.20 KXH30725.1 - 0.061 12.4 0.5 0.068 12.2 0.5 1.1 1 0 0 1 1 1 0 Phosphate transporter family OAD_gamma PF04277.13 KXH30725.1 - 0.14 12.8 2.3 0.76 10.4 1.0 2.0 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain DUF1129 PF06570.11 KXH30725.1 - 6.8 6.1 6.8 41 3.6 6.8 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1129) MFS_1 PF07690.16 KXH30726.1 - 5.6e-29 101.2 64.2 1.3e-26 93.3 36.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2781 PF10914.8 KXH30726.1 - 0.15 12.5 5.9 0.12 12.8 2.4 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2781) UPF0220 PF05255.11 KXH30726.1 - 2.8 7.5 7.6 0.34 10.5 2.2 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0220) NmrA PF05368.13 KXH30728.1 - 1.3e-36 126.3 0.0 1.8e-36 125.8 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXH30728.1 - 6.6e-15 55.5 0.0 8.3e-15 55.1 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KXH30728.1 - 0.00013 21.6 0.0 0.00017 21.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KXH30728.1 - 0.0065 15.7 0.0 0.13 11.4 0.0 2.1 1 1 1 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.19 KXH30728.1 - 0.013 14.5 0.0 0.019 13.9 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 KXH30728.1 - 0.015 15.2 0.2 0.025 14.5 0.2 1.3 1 0 0 1 1 1 0 KR domain Polysacc_synt_2 PF02719.15 KXH30728.1 - 0.019 14.1 0.0 0.037 13.2 0.0 1.4 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein DapB_N PF01113.20 KXH30728.1 - 0.15 12.2 0.0 0.32 11.1 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Epimerase PF01370.21 KXH30730.1 - 6.3e-15 55.3 0.0 2.8e-14 53.2 0.0 1.9 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXH30730.1 - 1.1e-12 47.6 0.0 2.4e-12 46.4 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KXH30730.1 - 3.2e-11 43.5 0.0 5.1e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KXH30730.1 - 5.9e-10 39.1 0.0 2.7e-09 36.9 0.0 1.9 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KXH30730.1 - 1.5e-08 34.2 0.0 4.3e-05 22.8 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein NmrA PF05368.13 KXH30730.1 - 5.3e-08 32.7 0.0 8e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.15 KXH30730.1 - 1.8e-05 24.0 0.0 2.9e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.25 KXH30730.1 - 0.00017 21.1 0.0 0.00061 19.3 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase RmlD_sub_bind PF04321.17 KXH30730.1 - 0.099 11.7 0.0 0.64 9.1 0.0 2.0 2 0 0 2 2 2 0 RmlD substrate binding domain Fungal_trans PF04082.18 KXH30731.1 - 3.2e-13 49.3 0.1 7.4e-13 48.1 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH30731.1 - 2.4e-09 37.2 11.8 3.8e-09 36.5 11.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_ribbon_SprT PF17283.2 KXH30731.1 - 1.4 8.9 11.2 3 7.9 11.2 1.5 1 0 0 1 1 1 0 SprT-like zinc ribbon domain Chitin_bind_1 PF00187.19 KXH30733.1 - 0.0023 18.4 17.5 0.0023 18.4 17.5 5.9 6 1 1 7 7 7 3 Chitin recognition protein Rpn3_C PF08375.11 KXH30735.1 - 5.1e-26 90.9 1.7 1.8e-25 89.1 1.7 2.0 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI PF01399.27 KXH30735.1 - 1.3e-20 73.9 0.1 4.5e-20 72.1 0.0 2.0 2 0 0 2 2 2 1 PCI domain TPR_2 PF07719.17 KXH30735.1 - 0.025 14.7 0.1 0.025 14.7 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TFIID_20kDa PF03847.13 KXH30736.1 - 5.5e-18 65.2 0.1 1.2e-17 64.2 0.1 1.6 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.23 KXH30736.1 - 0.018 15.3 1.0 0.12 12.7 0.0 2.6 3 0 0 3 3 3 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone AAA_11 PF13086.6 KXH30737.1 - 0.017 14.9 0.4 0.038 13.8 0.4 1.5 1 0 0 1 1 1 0 AAA domain UPF0242 PF06785.11 KXH30906.1 - 0.0089 16.2 2.1 0.0089 16.2 2.1 2.4 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0242) N-terminus zf-Di19 PF05605.12 KXH30906.1 - 0.017 15.4 0.0 0.042 14.1 0.0 1.7 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 KXH30906.1 - 0.039 14.8 0.1 0.099 13.5 0.1 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2HC_2 PF13913.6 KXH30906.1 - 0.057 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 zinc-finger of a C2HC-type zf-C2H2 PF00096.26 KXH30906.1 - 0.1 13.1 0.1 0.22 12.0 0.1 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-ribbon_3 PF13248.6 KXH30906.1 - 0.18 11.3 0.5 0.4 10.2 0.5 1.5 1 0 0 1 1 1 0 zinc-ribbon domain HALZ PF02183.18 KXH30906.1 - 0.22 11.8 6.1 0.97 9.7 3.1 2.7 2 0 0 2 2 2 0 Homeobox associated leucine zipper Chromo_shadow PF01393.19 KXH30907.1 - 1e-17 64.0 0.3 2.2e-17 62.9 0.3 1.6 1 0 0 1 1 1 1 Chromo shadow domain Chromo PF00385.24 KXH30907.1 - 0.00033 20.5 2.1 0.00063 19.6 0.1 2.5 2 1 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain AIG1 PF04548.16 KXH30907.1 - 0.22 10.8 0.0 0.38 10.0 0.0 1.4 1 0 0 1 1 1 0 AIG1 family HET PF06985.11 KXH30908.1 - 4.3e-11 43.4 10.1 5.1e-10 39.9 1.6 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Sec3_C PF09763.9 KXH30910.1 - 1.4e-242 807.1 2.5 1.7e-242 806.8 2.5 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.6 KXH30910.1 - 8.2e-29 99.6 0.0 1.7e-28 98.6 0.0 1.6 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Sec3_C_2 PF15278.6 KXH30910.1 - 0.01 16.1 0.0 0.031 14.6 0.0 1.8 1 0 0 1 1 1 0 Sec3 exocyst complex subunit Vps52 PF04129.12 KXH30910.1 - 2 7.0 8.1 0.054 12.2 0.3 2.1 3 0 0 3 3 3 0 Vps52 / Sac2 family HECT PF00632.25 KXH30911.1 - 9.6e-77 258.5 0.0 1.4e-76 257.9 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF1833 PF08875.11 KXH30911.1 - 0.03 13.9 0.1 0.07 12.7 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1833) HEAT PF02985.22 KXH30911.1 - 0.031 14.5 0.3 7.7 7.1 0.0 4.2 4 0 0 4 4 4 0 HEAT repeat Arm PF00514.23 KXH30911.1 - 0.041 13.9 11.5 58 3.9 0.0 7.4 7 2 2 9 9 9 0 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KXH30911.1 - 0.045 14.3 0.0 0.75 10.4 0.0 3.2 3 0 0 3 3 3 0 HEAT-like repeat CLASP_N PF12348.8 KXH30911.1 - 0.12 11.9 0.1 0.35 10.4 0.0 1.7 2 0 0 2 2 2 0 CLASP N terminal Telomere_reg-2 PF10193.9 KXH30911.1 - 0.56 10.7 2.3 6.7 7.2 0.1 3.3 3 0 0 3 3 3 0 Telomere length regulation protein TFIIA PF03153.13 KXH30911.1 - 0.75 9.7 36.4 0.035 14.1 18.5 2.9 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit E1_dh PF00676.20 KXH30913.1 - 1.5e-88 296.7 0.0 1.8e-88 296.4 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 KXH30913.1 - 0.00011 22.0 0.1 0.0063 16.3 0.0 2.9 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.6 KXH30913.1 - 0.11 11.7 0.0 0.27 10.4 0.0 1.6 2 0 0 2 2 2 0 1-deoxy-D-xylulose-5-phosphate synthase MFS_1 PF07690.16 KXH30914.1 - 3.7e-35 121.5 24.4 3.7e-35 121.5 24.4 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KXH30914.1 - 1.3e-06 28.0 3.3 1.3e-06 28.0 3.3 3.1 2 1 1 3 3 3 1 Uncharacterised MFS-type transporter YbfB DSRB PF10781.9 KXH30914.1 - 0.016 14.8 0.0 0.046 13.4 0.0 1.7 1 0 0 1 1 1 0 Dextransucrase DSRB Aminotran_4 PF01063.19 KXH30915.1 - 1.4e-30 106.8 0.0 2.6e-30 106.0 0.0 1.5 1 0 0 1 1 1 1 Amino-transferase class IV Fungal_trans PF04082.18 KXH30915.1 - 5.8e-22 78.0 0.4 8.7e-22 77.4 0.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH30915.1 - 2.9e-07 30.5 12.5 5.7e-07 29.5 12.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4094 PF13334.6 KXH30915.1 - 0.033 14.6 0.1 0.12 12.8 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) HalX PF08663.10 KXH30915.1 - 0.1 12.9 0.6 16 5.9 0.0 2.9 2 0 0 2 2 2 0 HalX domain DUF4328 PF14219.6 KXH30916.1 - 0.024 14.2 0.3 0.027 14.0 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) Ubie_methyltran PF01209.18 KXH30917.1 - 1e-76 257.4 0.0 1.3e-76 257.1 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 KXH30917.1 - 2.2e-15 57.1 0.0 3.8e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH30917.1 - 7.5e-14 52.2 0.0 1.7e-13 51.1 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH30917.1 - 2e-11 43.9 0.0 2.6e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH30917.1 - 2.9e-11 44.0 0.0 4.5e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXH30917.1 - 2.6e-08 33.9 0.0 4.4e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 KXH30917.1 - 0.015 15.2 0.0 0.056 13.3 0.0 1.9 3 0 0 3 3 3 0 Hypothetical methyltransferase ADH_zinc_N PF00107.26 KXH30917.1 - 0.15 12.0 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase DUF2433 PF10360.9 KXH30918.1 - 2e-49 166.8 0.0 3.1e-49 166.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) Metallophos PF00149.28 KXH30918.1 - 0.00051 20.6 0.0 0.0015 19.1 0.0 1.9 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KXH30918.1 - 0.013 15.7 0.0 0.039 14.1 0.0 1.8 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Zds_C PF08632.10 KXH30919.1 - 1.1e-27 95.5 1.4 2.1e-27 94.6 1.4 1.5 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term DUF2076 PF09849.9 KXH30919.1 - 0.12 12.4 0.1 0.12 12.4 0.1 5.3 4 2 1 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2076) adh_short_C2 PF13561.6 KXH30920.1 - 7.1e-57 192.7 7.2 9.2e-57 192.3 7.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXH30920.1 - 2e-48 164.5 5.0 2.7e-48 164.0 5.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXH30920.1 - 1.2e-13 51.3 3.9 2.4e-13 50.4 3.9 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXH30920.1 - 0.0061 16.0 2.3 0.015 14.8 2.3 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PNGaseA PF12222.8 KXH30920.1 - 0.02 13.8 1.2 0.029 13.3 0.0 1.7 2 0 0 2 2 2 0 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A Ketoacyl-synt_C PF02801.22 KXH30920.1 - 0.022 14.8 0.2 0.058 13.4 0.2 1.7 1 0 0 1 1 1 0 Beta-ketoacyl synthase, C-terminal domain THF_DHG_CYH_C PF02882.19 KXH30920.1 - 0.029 13.7 1.4 0.041 13.2 0.5 1.7 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.18 KXH30920.1 - 0.089 12.7 2.0 0.19 11.6 2.0 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain CDC14 PF08045.11 KXH30945.1 - 1.3e-131 437.9 0.0 1.5e-131 437.7 0.0 1.0 1 0 0 1 1 1 1 Cell division control protein 14, SIN component polyprenyl_synt PF00348.17 KXH30946.1 - 3.7e-66 222.8 0.0 4.6e-66 222.5 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Pex24p PF06398.11 KXH30947.1 - 4.4e-88 295.7 0.0 5.4e-88 295.4 0.0 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF3292 PF11696.8 KXH30947.1 - 0.033 12.6 1.4 0.038 12.4 0.6 1.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3292) Reticulon PF02453.17 KXH30947.1 - 0.18 11.8 3.7 0.79 9.7 3.7 1.9 1 1 0 1 1 1 0 Reticulon DUF4395 PF14340.6 KXH30947.1 - 0.97 9.8 7.2 5.4 7.4 0.1 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4395) CP2 PF04516.15 KXH30974.1 - 6.2e-86 287.4 0.0 8.7e-86 286.9 0.0 1.2 1 0 0 1 1 1 1 CP2 transcription factor Tektin PF03148.14 KXH30974.1 - 0.096 11.4 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 Tektin family AKNA PF12443.8 KXH30974.1 - 0.12 13.1 0.4 0.32 11.7 0.4 1.7 1 0 0 1 1 1 0 AT-hook-containing transcription factor TMF_DNA_bd PF12329.8 KXH30974.1 - 0.17 11.9 0.5 0.39 10.7 0.5 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Pyridox_oxase_2 PF12766.7 KXH30988.1 - 1.8e-18 67.0 0.0 3.1e-18 66.2 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase L27_N PF09060.10 KXH30989.1 - 0.024 14.7 0.2 0.059 13.4 0.2 1.7 1 0 0 1 1 1 0 L27_N P16-Arc PF04699.14 KXH30989.1 - 0.038 14.5 0.1 4 7.9 0.0 2.0 1 1 1 2 2 2 0 ARP2/3 complex 16 kDa subunit (p16-Arc) V_ATPase_I PF01496.19 KXH30991.1 - 5 4.9 6.8 9.7 4.0 6.8 1.7 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Fungal_trans PF04082.18 KXH30993.1 - 9.3e-42 142.9 0.0 1.5e-41 142.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH30993.1 - 3.8e-08 33.3 6.8 8.1e-08 32.3 6.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ank_2 PF12796.7 KXH30994.1 - 3.3e-10 40.4 0.0 0.00038 21.0 0.0 3.2 3 1 2 5 5 5 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXH30994.1 - 2.6e-07 31.1 0.1 0.00095 19.7 0.0 3.5 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 KXH30994.1 - 0.004 17.5 0.7 12 6.5 0.0 4.3 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 KXH30994.1 - 0.0046 17.3 0.0 3.3 8.1 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXH30994.1 - 0.13 12.9 0.1 2.9 8.7 0.0 3.2 3 0 0 3 3 3 0 Ankyrin repeat zf-RING_2 PF13639.6 KXH30995.1 - 8.2e-14 51.7 17.6 9.8e-14 51.4 7.7 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 KXH30995.1 - 1.8e-12 46.9 8.9 9.4e-09 35.0 3.0 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXH30995.1 - 1e-10 41.3 17.9 8.9e-10 38.3 7.4 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KXH30995.1 - 1.4e-10 40.7 2.7 1.4e-10 40.7 2.7 2.8 3 0 0 3 3 3 1 RING-like zinc finger zf-C3HC4 PF00097.25 KXH30995.1 - 4.4e-09 36.1 14.6 5e-07 29.5 6.0 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXH30995.1 - 1.2e-06 28.3 4.3 1.2e-06 28.3 4.3 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.7 KXH30995.1 - 1.5e-06 28.4 7.8 1.5e-06 28.4 7.8 2.4 2 0 0 2 2 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 KXH30995.1 - 1.3e-05 24.9 13.1 8.8e-05 22.3 5.3 2.3 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KXH30995.1 - 1.4e-05 25.0 1.2 1.4e-05 25.0 1.2 2.9 2 1 1 3 3 3 1 RING-type zinc-finger HypA PF01155.19 KXH30995.1 - 0.0026 17.7 0.4 0.0026 17.7 0.4 2.1 2 0 0 2 2 2 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-ANAPC11 PF12861.7 KXH30995.1 - 0.003 17.6 3.3 0.003 17.6 3.3 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_1 PF14446.6 KXH30995.1 - 0.08 12.9 13.1 0.3 11.0 2.8 3.4 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 zf-C3HC4_4 PF15227.6 KXH30995.1 - 0.085 13.0 14.1 0.53 10.5 2.3 2.8 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING Rad50_zn_hook PF04423.14 KXH30995.1 - 0.55 10.1 1.8 7.5 6.5 0.1 2.3 2 0 0 2 2 2 0 Rad50 zinc hook motif DZR PF12773.7 KXH30995.1 - 0.57 10.2 6.6 1.9 8.6 0.4 2.5 2 1 1 3 3 3 0 Double zinc ribbon zinc-ribbons_6 PF07191.12 KXH30995.1 - 1 9.4 9.9 0.79 9.8 1.3 2.6 2 1 0 2 2 2 0 zinc-ribbons PHD PF00628.29 KXH30995.1 - 1.2 9.0 15.3 3.8 7.5 1.7 2.5 2 0 0 2 2 2 0 PHD-finger zf-RING_4 PF14570.6 KXH30995.1 - 1.5 8.7 15.6 0.36 10.7 5.5 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-FPG_IleRS PF06827.14 KXH30995.1 - 4.3 7.3 6.7 14 5.7 0.3 2.9 3 0 0 3 3 3 0 Zinc finger found in FPG and IleRS Zn_ribbon_17 PF17120.5 KXH30995.1 - 9.2 6.0 17.3 5.5 6.7 6.1 2.4 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type Fis1_TPR_C PF14853.6 KXH30996.1 - 1.4e-25 89.1 1.0 2.6e-25 88.2 1.0 1.5 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.6 KXH30996.1 - 8.8e-18 63.7 0.1 1.4e-17 63.0 0.1 1.4 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.17 KXH30996.1 - 0.0051 16.8 1.4 0.0095 16.0 1.4 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat Spc24 PF08286.11 KXH30997.1 - 1.5e-37 128.0 3.7 1.2e-35 121.9 0.0 2.2 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 Miff PF05644.11 KXH30997.1 - 0.0061 16.2 3.6 0.0084 15.8 3.6 1.2 1 0 0 1 1 1 1 Mitochondrial and peroxisomal fission factor Mff V_ATPase_I PF01496.19 KXH30997.1 - 0.0091 14.0 1.5 0.0092 14.0 1.5 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family GTA_holin_3TM PF11351.8 KXH30997.1 - 0.051 14.1 0.7 0.051 14.1 0.7 2.1 1 1 1 2 2 2 0 Holin of 3TMs, for gene-transfer release Abi_C PF14355.6 KXH30997.1 - 0.094 12.8 4.6 0.3 11.2 1.6 2.8 2 2 2 4 4 3 0 Abortive infection C-terminus FUSC PF04632.12 KXH30997.1 - 0.11 11.1 2.5 0.1 11.1 2.5 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Retrotrans_gag PF03732.17 KXH30997.1 - 0.15 12.3 2.0 0.32 11.3 2.0 1.7 1 1 0 1 1 1 0 Retrotransposon gag protein Nsp1_C PF05064.13 KXH30997.1 - 0.19 11.5 5.3 0.62 9.9 0.5 2.3 1 1 1 2 2 2 0 Nsp1-like C-terminal region DUF4164 PF13747.6 KXH30997.1 - 0.33 11.2 14.6 17 5.8 14.6 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) XhlA PF10779.9 KXH30997.1 - 0.36 11.1 8.3 0.83 9.9 2.2 2.3 2 0 0 2 2 2 0 Haemolysin XhlA Laminin_II PF06009.12 KXH30997.1 - 0.52 10.3 8.5 0.61 10.1 5.5 2.0 1 1 1 2 2 2 0 Laminin Domain II CLZ PF16526.5 KXH30997.1 - 0.55 10.6 8.2 4.4 7.7 2.0 2.8 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF1690 PF07956.11 KXH30997.1 - 0.89 10.0 10.3 3.9 7.9 10.3 1.9 1 1 0 1 1 1 0 Protein of Unknown function (DUF1690) DUF2203 PF09969.9 KXH30997.1 - 1.6 9.5 6.0 2.6 8.8 5.6 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) OmpH PF03938.14 KXH30997.1 - 2.4 8.5 7.9 4.2 7.7 7.9 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) FlxA PF14282.6 KXH30997.1 - 2.5 8.1 12.1 2.9 7.9 0.9 2.6 1 1 1 2 2 2 0 FlxA-like protein SlyX PF04102.12 KXH30997.1 - 4.2 8.0 9.7 16 6.2 1.9 2.7 1 1 1 2 2 2 0 SlyX TatD_DNase PF01026.21 KXH30999.1 - 4.3e-32 111.5 0.0 6.1e-32 111.0 0.0 1.2 1 0 0 1 1 1 1 TatD related DNase Med3 PF11593.8 KXH31000.1 - 0.0026 17.0 3.9 0.0028 16.9 3.9 1.2 1 0 0 1 1 1 1 Mediator complex subunit 3 fungal Androgen_recep PF02166.16 KXH31000.1 - 0.017 14.0 6.0 0.021 13.7 6.0 1.2 1 0 0 1 1 1 0 Androgen receptor Spt20 PF12090.8 KXH31000.1 - 0.091 12.4 6.0 0.12 11.9 6.0 1.2 1 0 0 1 1 1 0 Spt20 family SUIM_assoc PF16619.5 KXH31000.1 - 0.28 11.3 10.1 0.75 9.9 10.1 1.8 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 V_ATPase_I PF01496.19 KXH31000.1 - 0.65 7.8 7.0 0.72 7.7 7.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4407 PF14362.6 KXH31000.1 - 1.1 8.5 9.5 1.4 8.2 9.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Pal1 PF08316.11 KXH31001.1 - 1.4e-09 38.8 0.2 5e-09 37.0 0.0 2.0 2 0 0 2 2 2 1 Pal1 cell morphology protein HVSL PF09749.9 KXH31002.1 - 1.3e-77 260.5 0.0 1.5e-77 260.3 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein ERO1 PF04137.15 KXH31003.1 - 1.5e-134 448.7 0.0 2.2e-134 448.1 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) PhyH PF05721.13 KXH31082.1 - 2.3e-21 77.1 0.1 3.1e-21 76.6 0.1 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) ABC_tran PF00005.27 KXH31086.1 - 2.8e-32 112.1 0.1 7e-32 110.8 0.0 1.7 2 0 0 2 2 2 1 ABC transporter ABC_membrane PF00664.23 KXH31086.1 - 1.1e-19 71.1 5.9 1.5e-19 70.8 5.9 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 KXH31086.1 - 1.6e-05 24.4 0.7 0.00051 19.5 0.1 2.2 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KXH31086.1 - 0.00018 21.9 0.1 0.0006 20.2 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KXH31086.1 - 0.0043 17.5 0.1 0.89 10.0 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KXH31086.1 - 0.012 15.9 0.1 0.059 13.7 0.1 2.1 1 1 0 1 1 1 0 AAA domain AAA_21 PF13304.6 KXH31086.1 - 0.015 15.2 0.1 0.25 11.1 0.0 2.2 1 1 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system ABC_ATPase PF09818.9 KXH31086.1 - 0.019 13.8 0.1 0.035 12.9 0.1 1.4 1 0 0 1 1 1 0 Predicted ATPase of the ABC class AAA_30 PF13604.6 KXH31086.1 - 0.028 14.1 0.0 0.74 9.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 KXH31086.1 - 0.03 14.2 0.0 0.096 12.6 0.0 1.8 1 1 0 1 1 1 0 RsgA GTPase AAA_28 PF13521.6 KXH31086.1 - 0.05 13.9 0.0 0.14 12.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KXH31086.1 - 0.05 13.6 0.0 0.33 11.0 0.0 2.1 1 1 1 2 2 2 0 AAA domain AAA_15 PF13175.6 KXH31086.1 - 0.07 12.8 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Zeta_toxin PF06414.12 KXH31086.1 - 0.074 12.3 0.0 0.32 10.3 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin SbcCD_C PF13558.6 KXH31086.1 - 0.097 12.9 0.3 0.93 9.8 0.3 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Rad17 PF03215.15 KXH31086.1 - 0.098 12.6 0.0 0.26 11.2 0.0 1.6 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_25 PF13481.6 KXH31086.1 - 0.11 12.1 0.0 0.34 10.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KXH31086.1 - 0.12 12.1 0.0 0.3 10.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_membrane PF00664.23 KXH31087.1 - 1.7e-68 231.3 33.2 2.1e-46 158.8 19.9 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KXH31087.1 - 6.6e-32 110.9 0.0 1.6e-31 109.6 0.0 1.7 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KXH31087.1 - 2.4e-06 27.1 2.5 0.00069 19.1 0.1 3.0 2 1 1 3 3 3 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KXH31087.1 - 0.00014 21.8 0.0 0.024 14.5 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 KXH31087.1 - 0.00049 19.8 0.7 0.0033 17.1 0.3 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.6 KXH31087.1 - 0.003 18.0 0.7 0.0081 16.6 0.1 1.9 1 1 1 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 KXH31087.1 - 0.018 14.6 0.2 0.084 12.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 KXH31087.1 - 0.091 12.4 0.2 0.33 10.6 0.3 1.9 1 1 0 1 1 1 0 AAA ATPase domain BCHF PF07284.11 KXH31087.1 - 0.76 9.8 0.0 0.76 9.8 0.0 3.2 3 0 0 3 3 3 0 2-vinyl bacteriochlorophyllide hydratase (BCHF) Fic PF02661.18 KXH31088.1 - 2.6e-11 44.3 0.0 6.1e-11 43.1 0.0 1.6 1 0 0 1 1 1 1 Fic/DOC family SARAF PF06682.12 KXH31089.1 - 1.6e-103 346.8 5.0 1.8e-103 346.7 5.0 1.0 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis BRE1 PF08647.11 KXH31090.1 - 1.4e-22 79.6 8.8 1.4e-22 79.6 8.8 6.8 4 2 2 6 6 5 2 BRE1 E3 ubiquitin ligase zf-C3HC4_3 PF13920.6 KXH31090.1 - 1.4e-08 34.5 7.5 2.4e-08 33.7 7.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KXH31090.1 - 7.6e-08 32.1 7.3 1.3e-07 31.3 7.3 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KXH31090.1 - 1.4e-07 31.3 10.7 2.5e-07 30.4 10.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXH31090.1 - 1.1e-06 28.6 6.4 2.1e-06 27.6 6.4 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KXH31090.1 - 1.7e-06 27.7 10.0 3.2e-06 26.9 10.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXH31090.1 - 6.8e-06 26.3 9.2 1.3e-05 25.4 9.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KXH31090.1 - 1.1e-05 25.3 10.4 2e-05 24.5 10.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain JIP_LZII PF16471.5 KXH31090.1 - 0.00053 20.1 2.0 0.00053 20.1 2.0 7.1 7 1 0 7 7 7 1 JNK-interacting protein leucine zipper II DivIC PF04977.15 KXH31090.1 - 0.001 18.8 2.1 0.001 18.8 2.1 10.0 7 3 3 10 10 10 2 Septum formation initiator DUF1664 PF07889.12 KXH31090.1 - 0.0033 17.4 2.0 0.0033 17.4 2.0 6.0 6 2 1 7 7 7 1 Protein of unknown function (DUF1664) TPR_MLP1_2 PF07926.12 KXH31090.1 - 0.0073 16.4 10.2 0.0073 16.4 10.2 7.3 3 2 2 6 6 6 2 TPR/MLP1/MLP2-like protein ATG16 PF08614.11 KXH31090.1 - 0.0087 16.3 16.9 0.0087 16.3 16.9 5.8 2 2 2 5 5 5 2 Autophagy protein 16 (ATG16) zf-C3HC4_4 PF15227.6 KXH31090.1 - 0.01 15.9 6.6 0.021 15.0 6.6 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING bZIP_1 PF00170.21 KXH31090.1 - 0.014 15.4 1.3 0.014 15.4 1.3 8.7 9 1 1 10 10 9 0 bZIP transcription factor zf-RING_4 PF14570.6 KXH31090.1 - 0.031 14.0 7.5 0.12 12.2 7.6 2.0 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain TerY_C PF15616.6 KXH31090.1 - 0.04 14.0 6.5 0.057 13.5 0.7 2.9 3 0 0 3 3 2 0 TerY-C metal binding domain zf-UDP PF14569.6 KXH31090.1 - 0.18 12.0 3.2 0.48 10.6 3.2 1.7 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-RING_6 PF14835.6 KXH31090.1 - 0.52 10.2 2.6 1 9.3 2.6 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 KXH31090.1 - 0.55 10.6 8.4 2.7 8.4 8.4 2.1 1 1 0 1 1 1 0 RING-H2 zinc finger domain DUF1272 PF06906.11 KXH31090.1 - 0.91 9.7 5.5 2.1 8.5 5.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-RING_10 PF16685.5 KXH31090.1 - 1 9.6 6.4 2.9 8.1 6.4 1.8 1 0 0 1 1 1 0 zinc RING finger of MSL2 DUF2935 PF11155.8 KXH31090.1 - 5.7 7.3 11.3 52 4.2 0.6 5.0 2 2 1 3 3 3 0 Domain of unknown function (DUF2935) MRP-S23 PF10484.9 KXH31090.1 - 6.8 7.0 9.7 42 4.4 0.1 4.2 3 1 1 4 4 4 0 Mitochondrial ribosomal protein S23 Myb_DNA-bind_7 PF15963.5 KXH31091.1 - 2.7e-24 84.9 0.2 2.7e-24 84.9 0.2 1.9 2 0 0 2 2 2 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 KXH31091.1 - 6e-05 23.1 0.0 0.00011 22.3 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KXH31091.1 - 0.08 13.2 0.0 0.2 11.9 0.0 1.8 1 1 0 1 1 1 0 Myb-like DNA-binding domain XPC-binding PF09280.11 KXH31092.1 - 1.9e-24 85.1 16.1 3.2e-24 84.4 16.1 1.4 1 0 0 1 1 1 1 XPC-binding domain UBA PF00627.31 KXH31092.1 - 1.8e-23 82.1 9.2 2.7e-13 49.5 0.5 2.9 2 0 0 2 2 2 2 UBA/TS-N domain ubiquitin PF00240.23 KXH31092.1 - 3.6e-14 52.3 0.0 6.2e-14 51.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KXH31092.1 - 0.0013 18.5 0.0 0.0022 17.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA_3 PF09288.10 KXH31092.1 - 0.0023 17.7 0.0 1.2 9.0 0.0 2.4 2 0 0 2 2 2 2 Fungal ubiquitin-associated domain MCM_N PF14551.6 KXH31092.1 - 0.015 15.9 0.1 0.032 14.8 0.1 1.5 1 0 0 1 1 1 0 MCM N-terminal domain Clathrin_H_link PF13838.6 KXH31092.1 - 0.018 14.9 3.1 0.018 14.9 3.1 2.4 2 0 0 2 2 2 0 Clathrin-H-link Rad60-SLD_2 PF13881.6 KXH31092.1 - 0.023 14.8 0.0 0.05 13.7 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Rib_recp_KP_reg PF05104.12 KXH31092.1 - 0.32 12.0 17.8 0.082 14.0 13.2 2.1 2 0 0 2 2 2 0 Ribosome receptor lysine/proline rich region Bac_rhodopsin PF01036.18 KXH31093.1 - 5.1e-32 111.2 23.4 6.7e-32 110.9 23.4 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein MCLC PF05934.11 KXH31093.1 - 2.4 6.8 4.3 3.4 6.3 4.3 1.2 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) Arm PF00514.23 KXH31094.1 - 2.7e-12 46.3 3.1 0.048 13.7 0.0 7.0 6 0 0 6 6 6 3 Armadillo/beta-catenin-like repeat HEAT PF02985.22 KXH31094.1 - 7.9e-05 22.6 10.9 26 5.4 0.0 7.7 7 0 0 7 7 7 0 HEAT repeat HEAT_EZ PF13513.6 KXH31094.1 - 0.00056 20.4 13.5 0.049 14.1 0.0 6.5 7 0 0 7 7 7 2 HEAT-like repeat TIMELESS PF04821.14 KXH31094.1 - 0.0013 18.1 2.1 0.97 8.7 0.0 3.8 4 0 0 4 4 4 1 Timeless protein DUF3361 PF11841.8 KXH31094.1 - 0.0083 16.1 1.7 5.6 6.9 0.0 3.4 3 0 0 3 3 3 2 Domain of unknown function (DUF3361) HEAT_2 PF13646.6 KXH31094.1 - 0.35 11.3 12.0 1.1 9.7 0.3 5.5 5 1 0 5 5 5 0 HEAT repeats DUF3636 PF12331.8 KXH31094.1 - 3.9 7.3 5.8 21 4.9 0.3 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF3636) Cyclin PF08613.11 KXH31095.1 - 1e-30 107.2 0.0 2.8e-30 105.8 0.0 1.8 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 KXH31095.1 - 0.0011 18.7 0.1 0.0021 17.8 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain CHZ PF09649.10 KXH31097.1 - 1.7e-18 65.8 2.1 1.7e-18 65.8 2.1 2.5 2 1 0 2 2 2 1 Histone chaperone domain CHZ GP24_25 PF17388.2 KXH31097.1 - 0.029 14.3 1.0 0.029 14.3 1.0 2.1 1 1 1 2 2 2 0 Tail assembly gene products 24 & 25 DUF4763 PF15960.5 KXH31097.1 - 1.2 8.4 3.4 1.3 8.3 3.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) Use1 PF09753.9 KXH31098.1 - 0.19 11.4 0.0 0.21 11.3 0.0 1.1 1 0 0 1 1 1 0 Membrane fusion protein Use1 Apc15p PF05841.11 KXH31099.1 - 2.4e-26 92.9 9.1 4.6e-26 92.0 9.1 1.5 1 0 0 1 1 1 1 Apc15p protein Spt20 PF12090.8 KXH31099.1 - 0.17 11.5 5.5 0.28 10.8 5.5 1.4 1 0 0 1 1 1 0 Spt20 family Inhibitor_I71 PF12628.7 KXH31099.1 - 1.2 8.9 3.0 17 5.2 0.1 2.2 2 0 0 2 2 2 0 Falstatin, cysteine peptidase inhibitor RNA_pol_Rpc4 PF05132.14 KXH31099.1 - 2.8 8.4 6.9 0.77 10.2 0.2 2.6 3 0 0 3 3 3 0 RNA polymerase III RPC4 GATase_2 PF00310.21 KXH31102.1 - 1.4e-182 607.1 0.0 1.9e-182 606.7 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 KXH31102.1 - 3.6e-155 516.6 0.0 5.6e-155 516.0 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 KXH31102.1 - 4.9e-111 370.7 0.0 3.1e-109 364.8 0.0 2.3 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.19 KXH31102.1 - 9.9e-88 292.7 2.7 1.7e-87 291.9 2.7 1.4 1 0 0 1 1 1 1 GXGXG motif Pyr_redox_2 PF07992.14 KXH31102.1 - 9e-23 80.9 0.1 5.1e-22 78.5 0.1 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 KXH31102.1 - 3.2e-21 75.2 0.1 7.1e-21 74.1 0.1 1.6 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster NAD_binding_8 PF13450.6 KXH31102.1 - 1.3e-08 34.9 0.0 4.5e-08 33.2 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXH31102.1 - 1.3e-07 31.6 0.5 0.00062 19.4 0.2 2.6 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 KXH31102.1 - 1.2e-06 29.0 0.1 0.00058 20.4 0.0 3.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KXH31102.1 - 1.8e-06 27.5 0.1 3.5e-06 26.6 0.1 1.5 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 KXH31102.1 - 4.5e-06 26.1 1.2 0.08 12.2 0.1 3.8 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXH31102.1 - 7.5e-05 22.0 0.0 0.00088 18.5 0.0 2.4 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 KXH31102.1 - 8.4e-05 21.4 0.1 8.4e-05 21.4 0.1 1.7 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 KXH31102.1 - 0.00017 21.1 0.1 0.00017 21.1 0.1 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KXH31102.1 - 0.00043 19.7 0.0 0.00095 18.5 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 KXH31102.1 - 0.0011 18.3 0.3 0.087 12.1 0.0 2.4 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 KXH31102.1 - 0.0022 18.4 0.5 1.1 9.8 0.1 3.0 3 0 0 3 3 2 1 Putative NAD(P)-binding Thi4 PF01946.17 KXH31102.1 - 0.0086 15.3 1.0 0.023 13.9 0.0 2.1 2 0 0 2 2 2 1 Thi4 family NAD_Gly3P_dh_N PF01210.23 KXH31102.1 - 0.01 15.8 0.0 0.024 14.6 0.0 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Lycopene_cycl PF05834.12 KXH31102.1 - 0.014 14.5 0.3 0.52 9.3 0.1 2.8 4 0 0 4 4 4 0 Lycopene cyclase protein GIDA PF01134.22 KXH31102.1 - 0.019 14.1 0.5 0.14 11.3 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A 2-Hacid_dh_C PF02826.19 KXH31102.1 - 0.033 13.5 0.0 0.36 10.2 0.0 2.5 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FMO-like PF00743.19 KXH31102.1 - 0.041 12.3 0.0 3.7 5.9 0.0 2.8 2 1 1 3 3 3 0 Flavin-binding monooxygenase-like FMN_dh PF01070.18 KXH31102.1 - 0.041 12.9 0.8 0.13 11.2 0.8 1.8 2 0 0 2 2 2 0 FMN-dependent dehydrogenase AdoHcyase_NAD PF00670.21 KXH31102.1 - 0.071 13.2 0.3 5.1 7.1 0.1 2.8 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain DUF1048 PF06304.11 KXH31102.1 - 0.082 13.4 0.8 0.26 11.8 0.3 2.1 2 0 0 2 2 1 0 Protein of unknown function (DUF1048) F420_oxidored PF03807.17 KXH31102.1 - 0.15 12.7 0.0 2.8 8.6 0.0 2.8 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Rossmann-like PF10727.9 KXH31102.1 - 0.52 10.2 1.7 3 7.7 0.0 2.6 2 0 0 2 2 2 0 Rossmann-like domain 6PF2K PF01591.18 KXH31103.1 - 2.8e-64 216.5 0.0 4.9e-46 156.8 0.0 2.2 2 0 0 2 2 2 2 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 KXH31103.1 - 1.8e-31 109.4 0.2 2.9e-25 89.1 0.0 2.5 3 0 0 3 3 3 2 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 KXH31103.1 - 0.0041 17.3 0.0 0.023 14.8 0.0 2.1 1 1 0 1 1 1 1 AAA domain Sigma70_r4_2 PF08281.12 KXH31103.1 - 0.015 15.0 0.1 2.1 8.1 0.0 2.6 2 0 0 2 2 2 0 Sigma-70, region 4 CARD PF00619.21 KXH31103.1 - 0.029 14.4 0.4 0.12 12.5 0.4 1.9 1 1 0 1 1 1 0 Caspase recruitment domain KTI12 PF08433.10 KXH31103.1 - 0.031 13.7 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 dCMP_cyt_deam_1 PF00383.23 KXH31104.1 - 3.2e-09 36.6 0.0 6.2e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KXH31104.1 - 0.0014 18.4 0.1 0.0029 17.4 0.1 1.4 1 0 0 1 1 1 1 MafB19-like deaminase Cauli_VI PF01693.16 KXH31105.1 - 1.9e-31 108.1 5.6 1.3e-17 63.8 1.5 2.4 2 0 0 2 2 2 2 Caulimovirus viroplasmin RNase_H PF00075.24 KXH31105.1 - 1.3e-30 106.5 0.0 2.5e-30 105.5 0.0 1.4 1 0 0 1 1 1 1 RNase H Na_H_Exchanger PF00999.21 KXH31106.1 - 3e-47 161.2 17.6 4e-47 160.8 17.6 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family TIG PF01833.24 KXH31107.1 - 1.9e-09 37.5 0.4 1.9e-09 37.5 0.4 2.6 3 0 0 3 3 3 1 IPT/TIG domain Ank PF00023.30 KXH31107.1 - 6.2e-08 32.8 0.1 6.1e-05 23.3 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 KXH31107.1 - 3.4e-07 30.8 0.0 7.2e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXH31107.1 - 1.1e-06 28.7 0.1 3.1e-06 27.4 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXH31107.1 - 2.5e-06 27.9 0.1 1e-05 25.9 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXH31107.1 - 4.4e-05 23.5 0.1 0.0077 16.7 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeat FAM60A PF15396.6 KXH31107.1 - 1.7 8.6 4.1 5.7 6.9 0.9 2.5 2 0 0 2 2 2 0 Protein Family FAM60A adh_short_C2 PF13561.6 KXH31109.1 - 1.6e-21 76.9 3.9 2e-14 53.7 0.5 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXH31109.1 - 7.1e-16 58.2 4.5 6e-10 38.9 0.4 2.5 3 0 0 3 3 3 2 short chain dehydrogenase KR PF08659.10 KXH31109.1 - 6.2e-07 29.5 1.3 1.4e-06 28.4 1.3 1.6 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 KXH31109.1 - 2.2e-05 24.7 1.1 3.6e-05 24.0 0.3 1.8 2 1 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain DAO PF01266.24 KXH31109.1 - 0.00068 19.3 6.4 0.062 12.9 2.6 2.3 1 1 1 2 2 2 2 FAD dependent oxidoreductase ApbA PF02558.16 KXH31109.1 - 0.0063 16.2 0.3 0.012 15.2 0.3 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3Beta_HSD PF01073.19 KXH31109.1 - 0.008 15.2 0.1 0.018 14.1 0.0 1.6 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family DUF1786 PF08735.10 KXH31109.1 - 0.12 11.7 0.3 0.3 10.3 0.2 1.7 1 1 1 2 2 2 0 Putative pyruvate format-lyase activating enzyme (DUF1786) Methyltransf_25 PF13649.6 KXH31109.1 - 0.12 13.0 0.1 1.6 9.5 0.0 2.4 2 1 1 3 3 3 0 Methyltransferase domain NAD_binding_2 PF03446.15 KXH31110.1 - 1.3e-21 77.4 1.2 1.7e-21 77.1 0.1 1.7 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 KXH31110.1 - 0.0012 18.9 0.0 0.0022 18.1 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 KXH31110.1 - 0.0069 15.8 0.0 0.015 14.7 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_11 PF14833.6 KXH31110.1 - 0.019 15.2 1.9 0.1 12.9 1.9 2.0 1 1 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 KXH31110.1 - 0.057 14.0 0.0 0.15 12.7 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Nic96 PF04097.14 KXH31111.1 - 1.1e-229 764.0 0.0 1.5e-229 763.6 0.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 Nucleoporin_FG PF13634.6 KXH31111.1 - 0.00018 22.3 85.4 0.26 12.1 50.2 4.3 2 1 1 3 3 3 2 Nucleoporin FG repeat region JmjC PF02373.22 KXH31112.1 - 3.2e-10 40.4 0.1 1e-09 38.8 0.1 1.8 1 1 0 1 1 1 1 JmjC domain, hydroxylase zf-4CXXC_R1 PF10497.9 KXH31112.1 - 1e-09 38.5 13.1 1e-09 38.5 13.1 2.5 2 0 0 2 2 2 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Cupin_2 PF07883.11 KXH31112.1 - 0.0035 17.0 0.0 0.0076 15.9 0.0 1.5 1 0 0 1 1 1 1 Cupin domain UbiA PF01040.18 KXH31113.1 - 2.5e-40 138.4 20.1 3.3e-40 138.0 20.1 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Ribosom_S12_S23 PF00164.25 KXH31114.1 - 3.5e-51 171.6 0.6 4.3e-51 171.3 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 DUF5315 PF17242.2 KXH31115.1 - 3.2e-29 100.6 2.1 5.8e-29 99.7 2.1 1.4 1 0 0 1 1 1 1 Disordered region of unknown function (DUF5315) Inhibitor_I9 PF05922.16 KXH31116.1 - 0.0025 18.4 0.0 0.0031 18.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase inhibitor I9 HOOK PF05622.12 KXH31117.1 - 1.8e-06 26.5 83.6 0.00028 19.2 52.3 4.1 2 1 2 4 4 4 3 HOOK protein Fez1 PF06818.15 KXH31117.1 - 0.39 11.2 66.4 0.31 11.5 24.9 4.1 1 1 2 3 3 3 0 Fez1 ADK PF00406.22 KXH31118.1 - 1.1e-49 168.5 0.2 4.8e-49 166.3 0.1 2.0 2 1 0 2 2 2 1 Adenylate kinase ADK_lid PF05191.14 KXH31118.1 - 7.3e-17 61.1 0.0 2.3e-16 59.4 0.0 1.9 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_17 PF13207.6 KXH31118.1 - 2.5e-14 53.9 0.5 1.1e-13 51.7 0.0 2.3 3 1 0 3 3 3 1 AAA domain Thymidylate_kin PF02223.17 KXH31118.1 - 0.0032 17.2 0.0 0.008 15.9 0.0 1.6 1 0 0 1 1 1 1 Thymidylate kinase Laminin_II PF06009.12 KXH31118.1 - 0.1 12.6 0.1 0.2 11.7 0.1 1.4 1 0 0 1 1 1 0 Laminin Domain II Trimer_CC PF08954.11 KXH31118.1 - 0.13 11.8 0.0 0.29 10.7 0.0 1.6 1 0 0 1 1 1 0 Trimerisation motif AAA_18 PF13238.6 KXH31118.1 - 0.16 12.5 0.5 0.35 11.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain BLOC1_2 PF10046.9 KXH31118.1 - 0.17 12.2 0.3 0.35 11.2 0.3 1.6 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Coleoptericin PF06286.11 KXH31119.1 - 0.043 13.9 0.0 0.057 13.5 0.0 1.3 1 0 0 1 1 1 0 Coleoptericin MitMem_reg PF13012.6 KXH31120.1 - 1.7e-37 128.3 0.1 5.8e-37 126.5 0.1 1.8 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function JAB PF01398.21 KXH31120.1 - 1.4e-30 105.7 0.0 3.2e-30 104.5 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease tRNA_bind_2 PF13725.6 KXH31120.1 - 0.017 14.9 6.1 0.025 14.3 6.1 1.2 1 0 0 1 1 1 0 Possible tRNA binding domain Connexin PF00029.19 KXH31120.1 - 0.6 9.8 2.9 0.87 9.3 2.9 1.2 1 0 0 1 1 1 0 Connexin SWIM PF04434.17 KXH31121.1 - 0.00034 20.2 0.7 0.31 10.8 0.1 2.5 2 0 0 2 2 2 2 SWIM zinc finger Nab1 PF04902.12 KXH31121.1 - 0.21 12.0 0.1 0.4 11.1 0.1 1.4 1 0 0 1 1 1 0 Conserved region in Nab1 Coprogen_oxidas PF01218.18 KXH31122.1 - 4.5e-145 481.9 0.1 5.4e-145 481.7 0.1 1.1 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase DUF1651 PF07864.11 KXH31122.1 - 0.0089 16.3 0.0 0.15 12.4 0.0 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1651) Atg8 PF02991.16 KXH31123.1 - 6.1e-51 171.0 0.3 1.3e-50 169.9 0.2 1.6 2 0 0 2 2 2 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 KXH31123.1 - 7e-06 26.4 0.0 1.4e-05 25.4 0.0 1.5 2 0 0 2 2 2 1 Ubiquitin-like autophagy protein Apg12 ABC_membrane PF00664.23 KXH31124.1 - 1.5e-88 297.0 26.2 3.8e-48 164.5 3.5 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KXH31124.1 - 1.1e-64 217.1 0.0 1.4e-32 113.1 0.0 2.8 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KXH31124.1 - 2.5e-16 59.8 0.7 5.3e-05 22.8 0.0 4.3 2 2 2 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 KXH31124.1 - 3.4e-07 30.2 3.8 0.012 15.3 0.0 4.5 5 0 0 5 5 4 2 AAA domain AAA_16 PF13191.6 KXH31124.1 - 5.8e-07 30.1 2.6 0.0035 17.7 0.3 3.3 2 2 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 KXH31124.1 - 2.2e-06 27.3 1.9 0.024 14.4 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_ATPase PF09818.9 KXH31124.1 - 3.8e-06 26.0 0.6 0.0043 15.9 0.0 2.6 2 0 0 2 2 2 2 Predicted ATPase of the ABC class RsgA_GTPase PF03193.16 KXH31124.1 - 6.2e-05 23.0 0.0 0.19 11.6 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase Zeta_toxin PF06414.12 KXH31124.1 - 8.8e-05 21.9 0.1 0.062 12.6 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_22 PF13401.6 KXH31124.1 - 9.8e-05 22.6 5.7 0.46 10.8 0.1 4.7 3 2 1 4 4 4 2 AAA domain APS_kinase PF01583.20 KXH31124.1 - 0.00017 21.5 0.2 0.054 13.4 0.1 2.4 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA PF00004.29 KXH31124.1 - 0.00041 20.8 0.4 1.5 9.2 0.0 4.3 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.6 KXH31124.1 - 0.0028 17.8 0.5 4.9 7.5 0.2 3.4 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.6 KXH31124.1 - 0.0032 17.6 0.2 1.7 8.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KXH31124.1 - 0.0054 16.3 0.4 11 5.6 0.0 3.8 4 0 0 4 4 4 0 AAA domain AAA_18 PF13238.6 KXH31124.1 - 0.011 16.2 0.8 5.8 7.5 0.0 2.8 2 1 0 2 2 2 0 AAA domain AAA_21 PF13304.6 KXH31124.1 - 0.013 15.3 4.2 0.33 10.7 0.0 3.6 3 1 1 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF3987 PF13148.6 KXH31124.1 - 0.025 13.6 8.2 0.49 9.3 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3987) AAA_23 PF13476.6 KXH31124.1 - 0.039 14.4 7.1 4.5 7.7 0.4 3.3 3 0 0 3 3 3 0 AAA domain PRK PF00485.18 KXH31124.1 - 0.042 13.6 0.2 1.7 8.4 0.0 2.6 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family SRP54 PF00448.22 KXH31124.1 - 0.055 13.1 0.4 9.2 5.8 0.1 2.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_15 PF13175.6 KXH31124.1 - 0.06 13.1 0.3 5.2 6.7 0.0 2.8 3 0 0 3 3 3 0 AAA ATPase domain AAA_5 PF07728.14 KXH31124.1 - 0.061 13.3 0.0 11 6.0 0.0 3.4 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 KXH31124.1 - 0.063 13.0 1.3 13 5.4 0.0 3.0 3 1 0 3 3 2 0 AAA domain DUF87 PF01935.17 KXH31124.1 - 0.08 13.0 4.0 1.1 9.3 0.2 3.0 3 0 0 3 3 3 0 Helicase HerA, central domain NB-ARC PF00931.22 KXH31124.1 - 0.12 11.5 0.6 12 5.0 0.0 2.6 2 0 0 2 2 2 0 NB-ARC domain Rad17 PF03215.15 KXH31124.1 - 0.13 12.2 0.0 0.34 10.8 0.0 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_17 PF13207.6 KXH31124.1 - 0.46 10.9 3.6 12 6.3 0.1 3.3 4 0 0 4 4 2 0 AAA domain MMR_HSR1 PF01926.23 KXH31124.1 - 0.6 10.2 2.3 29 4.8 0.0 3.2 3 0 0 3 3 2 0 50S ribosome-binding GTPase CAP59_mtransfer PF11735.8 KXH31138.1 - 7.8e-63 212.4 0.0 9.8e-63 212.1 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 DUF3090 PF11290.8 KXH31140.1 - 0.026 14.3 1.5 0.042 13.7 0.9 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3090) CorA PF01544.18 KXH31140.1 - 0.049 12.9 5.2 0.12 11.6 5.2 1.8 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein LUC7 PF03194.15 KXH31140.1 - 0.058 13.1 3.2 0.089 12.4 3.2 1.2 1 0 0 1 1 1 0 LUC7 N_terminus Pkinase PF00069.25 KXH31141.1 - 4.6e-16 59.0 0.0 1.9e-15 56.9 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXH31141.1 - 3.1e-06 26.7 0.0 3.8e-05 23.1 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXH31141.1 - 0.026 14.4 0.4 0.24 11.3 0.1 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family F-box-like PF12937.7 KXH31142.1 - 5.8e-09 35.7 1.1 1.2e-08 34.7 1.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXH31142.1 - 7.6e-07 28.9 2.1 1.4e-06 28.0 2.1 1.5 1 0 0 1 1 1 1 F-box domain Fungal_trans PF04082.18 KXH31143.1 - 4.1e-14 52.3 0.2 1.1e-13 50.9 0.2 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain RGP PF03214.13 KXH31143.1 - 0.15 11.2 0.0 0.23 10.6 0.0 1.2 1 0 0 1 1 1 0 Reversibly glycosylated polypeptide zf-C2H2_jaz PF12171.8 KXH31144.1 - 6.1e-07 29.6 3.2 1e-06 28.8 3.2 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KXH31144.1 - 0.00052 20.3 1.0 0.0009 19.6 1.0 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KXH31144.1 - 0.041 14.2 0.4 0.066 13.6 0.4 1.3 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 KXH31144.1 - 0.049 14.5 0.4 0.095 13.6 0.4 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KXH31144.1 - 0.053 14.0 0.9 0.09 13.3 0.9 1.4 1 0 0 1 1 1 0 Zinc finger, C2H2 type DUF1691 PF07950.11 KXH31145.1 - 3.2e-39 134.0 7.4 5.6e-33 113.9 5.7 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1691) DUF2955 PF11168.8 KXH31145.1 - 0.038 13.9 0.8 0.93 9.3 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2955) CFEM PF05730.11 KXH31146.1 - 7.6e-10 38.7 15.6 9.4e-10 38.5 15.6 1.1 1 0 0 1 1 1 1 CFEM domain Gamma-thionin PF00304.20 KXH31146.1 - 0.024 14.9 1.5 0.024 14.9 1.5 1.9 2 0 0 2 2 2 0 Gamma-thionin family PAN_4 PF14295.6 KXH31147.1 - 0.0071 16.2 1.1 0.015 15.2 1.1 1.5 1 0 0 1 1 1 1 PAN domain RAC_head PF16717.5 KXH31148.1 - 1.1e-31 109.6 1.3 1.1e-31 109.6 1.3 3.8 3 1 0 3 3 3 1 Ribosome-associated complex head domain DnaJ PF00226.31 KXH31148.1 - 7.4e-19 67.6 1.3 7.4e-19 67.6 1.3 2.6 2 0 0 2 2 2 1 DnaJ domain Complex1_LYR PF05347.15 KXH31149.1 - 0.032 14.3 0.1 0.058 13.5 0.1 1.5 1 0 0 1 1 1 0 Complex 1 protein (LYR family) DUF1681 PF07933.14 KXH31149.1 - 0.077 12.7 0.1 0.099 12.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1681) RRM_1 PF00076.22 KXH31150.1 - 4.9e-09 35.9 0.0 8.3e-09 35.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KXH31150.1 - 0.00046 20.0 0.0 0.00072 19.4 0.0 1.3 1 0 0 1 1 1 1 Occluded RNA-recognition motif RRM_3 PF08777.11 KXH31150.1 - 0.0079 16.2 0.0 0.016 15.3 0.0 1.4 1 0 0 1 1 1 1 RNA binding motif Nup35_RRM_2 PF14605.6 KXH31150.1 - 0.039 14.0 0.0 0.071 13.1 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Sterol_MT_C PF08498.10 KXH31151.1 - 3.1e-28 97.9 0.4 5.4e-28 97.1 0.4 1.4 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 KXH31151.1 - 1.4e-21 76.9 0.0 2.5e-21 76.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH31151.1 - 6.5e-20 71.7 0.0 1.3e-19 70.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH31151.1 - 2.5e-17 63.1 0.0 3.7e-17 62.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXH31151.1 - 4.7e-12 46.0 0.0 7.7e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXH31151.1 - 7.7e-11 41.8 0.0 1.5e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KXH31151.1 - 1.7e-10 41.5 0.0 3.3e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KXH31151.1 - 2.2e-10 40.3 0.0 3.5e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_29 PF03141.16 KXH31151.1 - 0.00073 18.2 0.0 0.001 17.7 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_15 PF09445.10 KXH31151.1 - 0.0009 18.9 0.0 0.0014 18.2 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PCMT PF01135.19 KXH31151.1 - 0.0011 18.7 0.0 0.0018 18.1 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.12 KXH31151.1 - 0.002 17.8 0.0 0.0034 17.0 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW PrmA PF06325.13 KXH31151.1 - 0.005 16.3 0.0 0.0081 15.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KXH31151.1 - 0.0051 16.4 0.0 0.0091 15.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.18 KXH31151.1 - 0.0084 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain RrnaAD PF00398.20 KXH31151.1 - 0.011 14.9 0.0 0.016 14.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_32 PF13679.6 KXH31151.1 - 0.024 14.6 0.0 0.044 13.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.14 KXH31151.1 - 0.04 13.3 0.0 0.067 12.6 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB CAP_N PF01213.19 KXH31151.1 - 0.22 11.0 1.3 0.33 10.4 1.3 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Transket_pyr PF02779.24 KXH31152.1 - 7.7e-46 156.0 0.0 1e-45 155.6 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KXH31152.1 - 1.2e-37 128.5 0.1 3.6e-37 127.0 0.1 1.9 2 0 0 2 2 2 1 Transketolase, C-terminal domain Aminotran_5 PF00266.19 KXH31152.1 - 0.13 11.1 0.0 0.26 10.2 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class-V FtsA PF14450.6 KXH31152.1 - 0.16 12.4 0.0 0.55 10.7 0.0 1.9 2 0 0 2 2 2 0 Cell division protein FtsA DSHCT PF08148.12 KXH31153.1 - 3.6e-52 176.3 0.2 9e-52 175.0 0.2 1.7 1 0 0 1 1 1 1 DSHCT (NUC185) domain Ski2_N PF17911.1 KXH31153.1 - 9.6e-38 129.1 0.0 6.2e-37 126.4 0.0 2.2 2 0 0 2 2 2 1 Ski2 N-terminal region rRNA_proc-arch PF13234.6 KXH31153.1 - 3.4e-30 105.9 0.0 5.6e-30 105.2 0.0 1.4 1 0 0 1 1 1 1 rRNA-processing arch domain DEAD PF00270.29 KXH31153.1 - 6.4e-19 68.4 0.0 1.6e-18 67.1 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXH31153.1 - 3.4e-06 27.4 0.0 1.6e-05 25.2 0.0 2.2 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXH31153.1 - 8.9e-06 25.8 0.1 6.7e-05 23.0 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF3516 PF12029.8 KXH31153.1 - 0.21 10.7 1.6 0.23 10.5 0.3 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3516) Snf7 PF03357.21 KXH31154.1 - 1.9e-06 27.6 24.5 1.9e-06 27.6 24.5 1.5 1 1 0 1 1 1 1 Snf7 Ist1 PF03398.14 KXH31154.1 - 0.00061 19.8 7.3 0.0014 18.5 7.3 1.6 1 1 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway CEL_III_C PF18054.1 KXH31154.1 - 2.4 8.2 6.0 3.6 7.7 6.0 1.3 1 0 0 1 1 1 0 CEL-III C-terminal Com_YlbF PF06133.11 KXH31154.1 - 7.3 7.3 23.4 0.17 12.5 13.6 2.6 2 1 0 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA NTP_transf_9 PF04248.12 KXH31155.1 - 8.5e-11 41.6 0.0 1.1e-10 41.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF427) bZIP_2 PF07716.15 KXH31156.1 - 7.4e-07 29.2 14.2 2.2e-06 27.7 14.2 1.9 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 KXH31156.1 - 2.1e-05 24.5 16.1 4.3e-05 23.5 16.1 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 KXH31156.1 - 0.0067 16.9 10.6 0.016 15.7 10.6 1.6 1 0 0 1 1 1 1 bZIP Maf transcription factor Swi3 PF07962.12 KXH31157.1 - 4.4e-31 106.7 0.3 6.7e-31 106.1 0.3 1.3 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 NADH-u_ox-rdase PF10785.9 KXH31158.1 - 1.3e-28 99.5 0.0 2.3e-28 98.7 0.0 1.4 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH_u_ox_C PF12853.7 KXH31158.1 - 4e-26 90.8 0.0 5.9e-26 90.3 0.0 1.2 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit Glyco_hydro_12 PF01670.16 KXH31159.1 - 5.5e-13 49.4 2.5 5.5e-13 49.4 2.5 1.9 2 1 0 2 2 2 1 Glycosyl hydrolase family 12 Mucin PF01456.17 KXH31159.1 - 0.0015 18.6 14.8 0.0023 17.9 14.8 1.3 1 0 0 1 1 1 1 Mucin-like glycoprotein SbcCD_C PF13558.6 KXH31159.1 - 0.1 12.8 0.5 0.19 12.0 0.5 1.4 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit DUF4512 PF14975.6 KXH31159.1 - 0.28 12.0 1.9 0.94 10.3 1.6 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4512) Fungal_trans PF04082.18 KXH31181.1 - 2.4e-09 36.6 0.0 4.2e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH31181.1 - 5.3e-07 29.7 7.5 8.8e-07 28.9 7.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain K-box PF01486.17 KXH31181.1 - 0.14 12.4 0.0 0.29 11.3 0.0 1.4 1 0 0 1 1 1 0 K-box region Med30 PF11315.8 KXH31181.1 - 0.14 12.4 0.2 0.35 11.1 0.2 1.7 1 0 0 1 1 1 0 Mediator complex subunit 30 AA_permease_2 PF13520.6 KXH31182.1 - 2.3e-64 217.8 45.8 2.6e-64 217.6 45.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXH31182.1 - 3.8e-22 78.5 39.4 5.2e-22 78.1 39.4 1.0 1 0 0 1 1 1 1 Amino acid permease Nucleos_tra2_N PF01773.20 KXH31182.1 - 0.28 11.8 0.2 0.28 11.8 0.2 3.3 4 0 0 4 4 4 0 Na+ dependent nucleoside transporter N-terminus Cu_amine_oxid PF01179.20 KXH31183.1 - 8.7e-166 551.9 0.0 1.2e-165 551.4 0.0 1.2 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.16 KXH31183.1 - 1.2e-06 28.6 0.0 3.1e-06 27.3 0.0 1.8 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.16 KXH31183.1 - 1.7e-06 28.3 0.0 3.6e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Glyco_hydro_11 PF00457.17 KXH31184.1 - 1.1e-74 249.9 16.8 1.3e-74 249.7 16.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 DUF924 PF06041.11 KXH31185.1 - 1.4e-51 175.2 0.0 2.6e-51 174.3 0.0 1.4 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF924) CrgA PF06781.12 KXH31186.1 - 1.4 9.0 3.6 2 8.5 0.1 2.3 2 0 0 2 2 2 0 Cell division protein CrgA DUF5071 PF16804.5 KXH31187.1 - 7.6e-34 116.5 0.3 3.6e-33 114.3 0.2 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF5071) RE_LlaMI PF09562.10 KXH31188.1 - 0.1 12.2 0.3 0.18 11.3 0.3 1.3 1 0 0 1 1 1 0 LlaMI restriction endonuclease NAD_binding_10 PF13460.6 KXH31189.1 - 2.8e-14 53.5 0.0 4.2e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KXH31189.1 - 1.2e-13 51.1 0.1 2.5e-13 50.1 0.1 1.5 1 1 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 KXH31189.1 - 0.0024 17.4 0.0 0.0051 16.3 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.20 KXH31189.1 - 0.036 14.2 0.2 0.096 12.8 0.1 1.8 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.24 KXH31189.1 - 0.17 12.3 0.9 0.7 10.3 0.1 2.4 3 0 0 3 3 3 0 Semialdehyde dehydrogenase, NAD binding domain DUF4937 PF16291.5 KXH31190.1 - 0.0035 17.5 0.5 0.1 12.8 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4937 ABM PF03992.16 KXH31190.1 - 0.09 12.9 0.1 0.84 9.8 0.0 2.1 2 0 0 2 2 2 0 Antibiotic biosynthesis monooxygenase Trp_DMAT PF11991.8 KXH31191.1 - 3.3e-102 342.6 0.0 3.9e-102 342.4 0.0 1.0 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase FAD_binding_4 PF01565.23 KXH31192.1 - 2.1e-24 85.8 0.0 4.5e-24 84.8 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.19 KXH31192.1 - 1.3e-11 44.7 0.0 1.9e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain adh_short PF00106.25 KXH31193.1 - 1.6e-39 135.4 0.0 2.7e-39 134.6 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXH31193.1 - 2.3e-25 89.5 0.0 4e-25 88.7 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH31193.1 - 2.4e-13 50.4 0.0 3.3e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXH31193.1 - 3e-07 30.2 0.0 3.7e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KXH31193.1 - 0.00034 20.6 0.0 0.00047 20.1 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KXH31193.1 - 0.0013 17.9 0.0 0.0018 17.5 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DUF1194 PF06707.11 KXH31193.1 - 0.0051 16.0 0.0 0.0072 15.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1194) TerD PF02342.18 KXH31193.1 - 0.069 12.6 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 TerD domain Methyltransf_25 PF13649.6 KXH31193.1 - 0.11 13.3 0.0 0.21 12.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Glyco_tran_WecB PF03808.13 KXH31193.1 - 0.19 11.6 0.0 0.91 9.5 0.0 2.2 2 1 0 3 3 3 0 Glycosyl transferase WecB/TagA/CpsF family CN_hydrolase PF00795.22 KXH31194.1 - 8.6e-45 153.1 0.0 1.5e-44 152.3 0.0 1.4 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Fungal_trans PF04082.18 KXH31195.1 - 1.6e-15 56.9 0.7 1.6e-15 56.9 0.7 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF1264 PF06884.11 KXH31197.1 - 5.7e-77 257.1 0.4 6.7e-77 256.9 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1264) RyR PF02026.16 KXH31198.1 - 0.21 11.8 0.0 0.39 10.9 0.0 1.4 1 0 0 1 1 1 0 RyR domain Egh16-like PF11327.8 KXH31200.1 - 1.7e-53 181.8 14.0 1.7e-53 181.8 14.0 1.6 2 0 0 2 2 2 1 Egh16-like virulence factor Glyco_hydro_7 PF00840.20 KXH31201.1 - 6.5e-198 657.8 22.2 7.4e-198 657.6 22.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 HAD_2 PF13419.6 KXH31202.1 - 6.5e-13 49.2 0.0 8.5e-13 48.8 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KXH31202.1 - 5.7e-10 39.8 0.0 2.5e-09 37.7 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KXH31202.1 - 2.2e-05 24.4 0.0 3.9e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Acid_PPase PF12689.7 KXH31202.1 - 0.11 12.4 0.0 0.53 10.1 0.0 1.9 2 0 0 2 2 2 0 Acid Phosphatase Glyco_hydro_61 PF03443.14 KXH31203.1 - 0.0016 18.4 0.0 0.0052 16.8 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 MaoC_dehydratas PF01575.19 KXH31203.1 - 0.095 12.3 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 MaoC like domain PAS_9 PF13426.7 KXH31204.1 - 5.2e-15 55.6 0.0 8.4e-15 54.9 0.0 1.4 1 0 0 1 1 1 1 PAS domain PAS_3 PF08447.12 KXH31204.1 - 0.0072 16.6 0.0 0.016 15.5 0.0 1.6 1 0 0 1 1 1 1 PAS fold Hydrolase_4 PF12146.8 KXH31206.1 - 7.4e-12 45.1 0.1 4.9e-08 32.5 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KXH31206.1 - 3e-10 41.1 2.4 4.6e-10 40.5 2.4 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXH31206.1 - 6.6e-07 29.2 0.1 0.00054 19.7 0.1 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KXH31206.1 - 3e-05 23.6 1.1 0.16 11.4 0.2 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family LIP PF03583.14 KXH31206.1 - 0.00031 20.2 1.0 0.012 14.9 0.3 2.1 2 0 0 2 2 2 1 Secretory lipase DLH PF01738.18 KXH31206.1 - 0.00062 19.4 0.1 0.038 13.6 0.0 2.1 2 0 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S8 PF00082.22 KXH31209.1 - 3.7e-32 111.8 10.6 5.5e-32 111.2 10.7 1.3 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 KXH31209.1 - 5.1e-16 59.1 0.2 5.1e-16 59.1 0.2 1.7 2 0 0 2 2 2 1 Peptidase inhibitor I9 Flavin_Reduct PF01613.18 KXH31210.1 - 1.3e-17 64.2 0.0 1.9e-17 63.8 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain Sugar_tr PF00083.24 KXH31211.1 - 6.6e-72 242.8 20.7 7.9e-72 242.5 20.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH31211.1 - 2.5e-26 92.5 27.1 3.4e-26 92.0 27.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 KXH31211.1 - 9.1e-07 27.8 0.9 9.1e-07 27.8 0.9 3.4 2 1 0 3 3 3 2 MFS/sugar transport protein TRI12 PF06609.13 KXH31211.1 - 0.0017 16.8 4.5 0.0022 16.5 0.4 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) 7tm_1 PF00001.21 KXH31211.1 - 0.024 14.0 1.0 0.043 13.2 1.0 1.4 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) LCCL PF03815.19 KXH31213.1 - 4.7e-19 68.3 0.0 8e-19 67.5 0.0 1.3 1 0 0 1 1 1 1 LCCL domain Acetyltransf_1 PF00583.25 KXH31214.1 - 2.3e-06 27.8 0.0 4.5e-06 26.9 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXH31214.1 - 0.065 13.7 0.0 0.12 12.8 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXH31215.1 - 2.4e-09 37.5 0.0 3.2e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXH31215.1 - 1.7e-06 28.3 0.0 2.6e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KXH31215.1 - 2.8e-05 24.1 0.0 4.1e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Glyco_hydro2_C5 PF18565.1 KXH31216.1 - 3.8e-33 113.4 0.4 7.2e-33 112.5 0.4 1.5 1 0 0 1 1 1 1 Glycoside hydrolase family 2 C-terminal domain 5 Glyco_hydro_2_C PF02836.17 KXH31216.1 - 1.3e-24 86.9 0.1 3.3e-24 85.5 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain DUF4982 PF16355.5 KXH31216.1 - 4e-23 81.1 0.1 8.8e-23 80.0 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4982) Glyco_hydro_2 PF00703.21 KXH31216.1 - 1e-15 58.4 0.5 2.2e-15 57.3 0.5 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.18 KXH31216.1 - 2.3e-13 50.4 0.0 6.6e-13 48.9 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain BetaGal_dom4_5 PF13364.6 KXH31216.1 - 1.7e-06 28.6 0.1 3.2e-05 24.5 0.0 3.0 3 0 0 3 3 3 1 Beta-galactosidase jelly roll domain Invasin_D3 PF09134.10 KXH31216.1 - 9e-06 25.9 6.4 6.9e-05 23.1 0.4 3.2 2 0 0 2 2 2 1 Invasin, domain 3 Big_1 PF02369.16 KXH31216.1 - 0.003 17.5 0.9 0.003 17.5 0.9 3.5 4 0 0 4 4 4 1 Bacterial Ig-like domain (group 1) Asp PF00026.23 KXH31217.1 - 3.5e-38 131.8 0.7 4.5e-38 131.4 0.7 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KXH31217.1 - 3.3e-06 27.5 0.5 0.00015 22.0 0.3 2.9 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KXH31217.1 - 0.0053 17.4 0.8 3.9 8.2 0.1 3.4 2 1 1 3 3 3 2 Aspartyl protease PGAP1 PF07819.13 KXH31218.1 - 0.0031 17.2 0.0 0.0083 15.9 0.0 1.6 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 KXH31218.1 - 0.0099 16.5 0.1 0.021 15.4 0.1 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXH31218.1 - 0.087 12.1 0.0 0.77 9.0 0.0 2.3 2 0 0 2 2 2 0 Serine aminopeptidase, S33 zf-RING_2 PF13639.6 KXH31220.1 - 1.2e-13 51.2 6.2 1.8e-13 50.6 6.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KXH31220.1 - 8.8e-11 41.5 7.0 1.4e-10 40.8 7.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXH31220.1 - 4.6e-10 39.2 3.9 7.5e-10 38.5 3.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXH31220.1 - 3.3e-09 36.6 5.4 6.4e-09 35.7 5.4 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KXH31220.1 - 9.5e-09 35.0 3.3 1.5e-08 34.3 3.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXH31220.1 - 3.7e-07 30.0 5.2 8.8e-07 28.8 5.3 1.6 1 1 1 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KXH31220.1 - 4.7e-07 29.6 8.9 7.3e-07 29.0 3.4 2.2 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KXH31220.1 - 5.8e-06 26.4 7.3 1.5e-05 25.1 7.3 1.7 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.5 KXH31220.1 - 1.8e-05 24.4 2.7 3.3e-05 23.5 2.7 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 KXH31220.1 - 7.2e-05 23.0 9.9 0.00038 20.7 9.9 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KXH31220.1 - 0.00057 19.9 0.9 0.00091 19.2 0.9 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Rad50_zn_hook PF04423.14 KXH31220.1 - 0.003 17.4 0.2 0.28 11.0 0.0 2.3 2 0 0 2 2 2 1 Rad50 zinc hook motif Phage_holin_3_6 PF07332.11 KXH31220.1 - 0.013 15.5 0.1 0.021 14.8 0.1 1.3 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Vps39_2 PF10367.9 KXH31220.1 - 0.022 15.2 0.9 0.04 14.4 0.2 1.7 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 Zn_ribbon_17 PF17120.5 KXH31220.1 - 0.078 12.6 4.4 0.13 11.9 4.4 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 KXH31220.1 - 0.13 12.1 7.0 1.2 9.0 7.1 2.1 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain FdhE PF04216.12 KXH31220.1 - 0.14 12.0 2.4 0.22 11.3 2.4 1.3 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation C1_2 PF03107.16 KXH31220.1 - 0.16 12.3 4.9 0.69 10.3 4.9 2.0 1 1 0 1 1 1 0 C1 domain FYVE PF01363.21 KXH31220.1 - 0.32 11.2 5.0 1.6 8.9 5.0 2.1 1 1 0 1 1 1 0 FYVE zinc finger zf-P11 PF03854.14 KXH31220.1 - 0.35 10.6 5.9 0.23 11.2 3.1 1.9 2 0 0 2 2 2 0 P-11 zinc finger zf-RING_6 PF14835.6 KXH31220.1 - 0.95 9.4 5.8 2.2 8.2 5.8 1.6 1 1 0 1 1 1 0 zf-RING of BARD1-type protein zf-H2C2_2 PF13465.6 KXH31220.1 - 4.8 7.8 7.4 16 6.1 0.6 2.9 3 0 0 3 3 2 0 Zinc-finger double domain GGACT PF06094.12 KXH31221.1 - 1.1e-10 42.2 0.2 2.1e-10 41.2 0.2 1.5 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like BTB PF00651.31 KXH31222.1 - 0.0013 19.0 0.0 0.0029 17.8 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Aa_trans PF01490.18 KXH31223.1 - 5e-34 117.7 31.0 5.8e-34 117.5 31.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Herpes_UL79 PF03049.14 KXH31223.1 - 0.044 13.4 0.2 0.072 12.8 0.2 1.3 1 0 0 1 1 1 0 UL79 family Peroxidase_2 PF01328.17 KXH31224.1 - 8e-44 150.4 0.1 1e-43 150.0 0.1 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 Fungal_trans PF04082.18 KXH31225.1 - 3e-12 46.1 0.0 5e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH31225.1 - 1.3e-08 34.8 10.2 2.4e-08 33.9 10.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 KXH31226.1 - 2.3e-19 69.6 20.6 2.3e-19 69.6 20.6 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH31226.1 - 8.7e-09 34.7 2.7 8.7e-09 34.7 2.7 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter PhyH PF05721.13 KXH31227.1 - 5.2e-07 30.1 0.0 9.5e-07 29.3 0.0 1.4 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 KXH31227.1 - 5.7e-06 25.3 0.0 0.026 13.3 0.0 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF1479) 2OG-FeII_Oxy_5 PF13759.6 KXH31227.1 - 0.0079 16.6 0.0 0.015 15.7 0.0 1.4 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase 2OG-FeII_Oxy_3 PF13640.6 KXH31227.1 - 0.15 12.9 0.0 0.41 11.6 0.0 1.7 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily PepX_C PF08530.10 KXH31228.1 - 6.5e-39 134.2 0.0 1e-38 133.6 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Peptidase_S15 PF02129.18 KXH31228.1 - 1.4e-35 123.2 4.0 1.8e-29 103.2 0.0 2.1 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) CN_hydrolase PF00795.22 KXH31230.1 - 2.4e-43 148.4 0.2 1.4e-42 145.8 0.2 2.0 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase Amdase PF17645.1 KXH31236.1 - 6.7e-16 58.6 0.0 8.2e-16 58.3 0.0 1.1 1 0 0 1 1 1 1 Arylmalonate decarboxylase B12-binding PF02310.19 KXH31236.1 - 0.024 14.7 0.2 2.5 8.2 0.0 3.0 1 1 1 3 3 3 0 B12 binding domain ABC_tran PF00005.27 KXH31237.1 - 5.8e-43 146.7 0.0 8.7e-26 91.1 0.1 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KXH31237.1 - 4.8e-33 115.0 31.5 1.8e-32 113.1 10.0 2.6 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 KXH31237.1 - 6e-14 52.0 1.9 0.0043 16.5 0.0 4.2 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KXH31237.1 - 3.1e-07 30.5 1.6 0.05 13.4 0.0 4.2 3 1 1 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KXH31237.1 - 6.6e-07 29.7 0.3 0.032 14.5 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA PF00004.29 KXH31237.1 - 2.4e-06 28.0 0.1 0.27 11.6 0.1 3.6 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 KXH31237.1 - 2.4e-06 27.6 0.5 0.03 14.3 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_7 PF12775.7 KXH31237.1 - 4e-05 23.2 0.4 0.28 10.7 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region IstB_IS21 PF01695.17 KXH31237.1 - 9.2e-05 22.2 0.8 1 9.0 0.0 3.6 3 0 0 3 3 3 1 IstB-like ATP binding protein T2SSE PF00437.20 KXH31237.1 - 0.00025 20.2 0.1 0.012 14.7 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_16 PF13191.6 KXH31237.1 - 0.0004 20.8 1.0 0.78 10.1 0.0 3.3 3 1 0 3 3 2 2 AAA ATPase domain AAA_29 PF13555.6 KXH31237.1 - 0.00076 19.2 1.1 1.2 8.9 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain SbcCD_C PF13558.6 KXH31237.1 - 0.0014 18.8 0.1 3.8 7.8 0.1 3.1 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit DEAD PF00270.29 KXH31237.1 - 0.0021 17.9 0.5 2.5 7.9 0.0 2.7 2 0 0 2 2 2 2 DEAD/DEAH box helicase AAA_33 PF13671.6 KXH31237.1 - 0.0022 18.2 0.6 0.86 9.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KXH31237.1 - 0.003 17.9 0.2 8 6.9 0.0 3.3 3 0 0 3 3 3 0 RNA helicase Roc PF08477.13 KXH31237.1 - 0.006 16.8 0.1 3.5 7.9 0.0 2.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_11 PF13086.6 KXH31237.1 - 0.011 15.6 0.2 2.2 8.0 0.0 2.8 3 0 0 3 3 3 0 AAA domain Dynamin_N PF00350.23 KXH31237.1 - 0.011 15.8 1.2 1.5 8.8 0.0 3.0 3 0 0 3 3 3 0 Dynamin family Septin PF00735.18 KXH31237.1 - 0.011 15.0 0.1 4.6 6.4 0.0 2.5 2 0 0 2 2 2 0 Septin AAA_15 PF13175.6 KXH31237.1 - 0.012 15.4 0.2 4.4 6.9 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain cobW PF02492.19 KXH31237.1 - 0.013 15.1 0.4 3.1 7.4 0.1 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.6 KXH31237.1 - 0.018 14.8 0.6 0.064 13.0 0.1 2.2 2 1 0 2 2 2 0 AAA domain AAA_5 PF07728.14 KXH31237.1 - 0.025 14.6 1.0 21 5.1 0.0 3.6 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) ATPase_2 PF01637.18 KXH31237.1 - 0.026 14.4 0.1 6.1 6.7 0.0 2.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Pox_A32 PF04665.12 KXH31237.1 - 0.035 13.6 0.1 0.12 11.9 0.1 1.9 1 0 0 1 1 1 0 Poxvirus A32 protein NACHT PF05729.12 KXH31237.1 - 0.037 14.0 0.3 9.8 6.1 0.1 2.7 2 0 0 2 2 2 0 NACHT domain AAA_23 PF13476.6 KXH31237.1 - 0.037 14.5 0.4 6.6 7.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 KXH31237.1 - 0.05 13.6 0.1 3.4 7.7 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PRK PF00485.18 KXH31237.1 - 0.066 12.9 0.4 0.18 11.5 0.1 1.8 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family NB-ARC PF00931.22 KXH31237.1 - 0.074 12.2 2.8 0.42 9.8 0.1 3.0 3 1 0 3 3 3 0 NB-ARC domain AAA_25 PF13481.6 KXH31237.1 - 0.086 12.4 0.7 4.2 6.9 0.1 3.2 3 0 0 3 3 3 0 AAA domain MMR_HSR1 PF01926.23 KXH31237.1 - 0.11 12.6 0.0 5.9 7.0 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_PrkA PF08298.11 KXH31237.1 - 0.15 10.9 0.3 1.1 8.0 0.0 2.1 2 0 0 2 2 2 0 PrkA AAA domain NTPase_1 PF03266.15 KXH31237.1 - 0.16 11.9 3.6 0.46 10.4 0.0 3.0 3 0 0 3 3 3 0 NTPase ATP_bind_1 PF03029.17 KXH31237.1 - 0.28 10.9 3.6 0.73 9.6 0.1 2.7 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein Rad17 PF03215.15 KXH31237.1 - 0.41 10.5 3.7 11 5.9 0.1 3.0 3 0 0 3 3 3 0 Rad17 P-loop domain DUF3824 PF12868.7 KXH31238.1 - 0.077 13.7 0.4 0.28 11.9 0.1 2.0 2 0 0 2 2 2 0 Domain of unknwon function (DUF3824) Sugar_tr PF00083.24 KXH31239.1 - 2.7e-116 389.1 26.0 3.1e-116 388.9 26.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH31239.1 - 6.9e-21 74.5 54.3 1.2e-17 63.9 27.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily CDP-OH_P_transf PF01066.21 KXH31282.1 - 9.1e-17 61.6 0.1 9.1e-17 61.6 0.1 3.4 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Adaptin_N PF01602.20 KXH31283.1 - 4.9e-115 385.1 0.8 6.3e-115 384.7 0.8 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 KXH31283.1 - 8.3e-55 185.1 5.1 2e-54 183.8 5.1 1.7 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 KXH31283.1 - 2.9e-37 127.3 0.3 8.3e-37 125.8 0.3 1.9 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 KXH31283.1 - 8.1e-18 64.6 1.1 3.4e-12 46.6 0.0 5.2 2 1 4 6 6 6 1 HEAT repeats Cnd1 PF12717.7 KXH31283.1 - 2.1e-07 31.1 9.4 0.026 14.6 0.1 4.9 4 1 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 KXH31283.1 - 0.0017 17.9 6.0 0.0038 16.8 0.2 3.2 4 0 0 4 4 4 1 CLASP N terminal HEAT_PBS PF03130.16 KXH31283.1 - 0.0022 18.5 0.1 1.5 9.7 0.0 4.0 3 0 0 3 3 3 1 PBS lyase HEAT-like repeat HEAT PF02985.22 KXH31283.1 - 0.024 14.9 6.6 2.2 8.8 0.2 5.4 5 0 0 5 5 5 0 HEAT repeat Coatomer_b_Cpla PF14806.6 KXH31283.1 - 0.045 13.7 0.0 0.26 11.3 0.0 2.2 2 0 0 2 2 2 0 Coatomer beta subunit appendage platform RTP1_C1 PF10363.9 KXH31283.1 - 0.053 13.7 0.6 3.2 8.0 0.0 3.5 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 DUF5010 PF16402.5 KXH31283.1 - 0.071 11.9 0.0 0.15 10.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5010) HEAT_EZ PF13513.6 KXH31283.1 - 1.6 9.3 4.5 1.5 9.5 0.6 2.9 3 0 0 3 3 3 0 HEAT-like repeat Svs_4_5_6 PF17381.2 KXH31284.1 - 3.3 8.7 6.3 1.6 9.7 1.7 2.5 2 0 0 2 2 2 0 Seminal vesicle secretory proteins 4/5/6 Zn_clus PF00172.18 KXH31288.1 - 3.4e-07 30.3 4.9 7.8e-07 29.1 4.9 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 KXH31289.1 - 7.2e-15 54.8 33.0 2.1e-10 40.1 24.0 2.9 1 1 2 3 3 3 3 Major Facilitator Superfamily PAN_1 PF00024.26 KXH31290.1 - 0.0024 17.8 0.2 0.0024 17.8 0.2 2.0 1 1 1 2 2 2 1 PAN domain PAN_4 PF14295.6 KXH31290.1 - 0.023 14.6 0.9 0.023 14.6 0.9 2.0 2 1 0 2 2 2 0 PAN domain Sugar_tr PF00083.24 KXH31337.1 - 2.8e-85 286.9 32.1 2.1e-48 165.3 11.4 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KXH31337.1 - 2e-19 69.8 45.9 1.7e-18 66.7 12.1 2.8 2 1 1 3 3 3 3 Major Facilitator Superfamily DUF3007 PF11460.8 KXH31337.1 - 0.14 12.4 0.6 0.49 10.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3007) Fungal_trans_2 PF11951.8 KXH31338.1 - 1.9e-08 33.5 0.2 3.4e-08 32.7 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain p450 PF00067.22 KXH31339.1 - 6.5e-68 229.5 0.0 9.4e-68 229.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 CFEM PF05730.11 KXH31340.1 - 0.00026 21.0 2.2 0.00058 19.9 2.2 1.6 1 0 0 1 1 1 1 CFEM domain ET PF01684.16 KXH31340.1 - 0.088 13.2 3.4 1.2 9.5 1.3 2.9 3 0 0 3 3 3 0 ET module Hydrophobin_2 PF06766.11 KXH31341.1 - 2.4e-19 69.0 8.5 3.2e-19 68.6 8.5 1.1 1 0 0 1 1 1 1 Fungal hydrophobin DUF3703 PF12487.8 KXH31341.1 - 0.2 11.5 0.1 0.39 10.5 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3703) MFS_1 PF07690.16 KXH31342.1 - 9.6e-14 51.1 26.6 9.6e-14 51.1 26.6 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 KXH31342.1 - 4.4e-11 42.7 4.7 4.4e-11 42.7 4.7 1.9 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 Sugar_tr PF00083.24 KXH31342.1 - 1.3e-05 24.3 3.6 1.3e-05 24.3 3.6 1.6 2 0 0 2 2 2 1 Sugar (and other) transporter TauD PF02668.16 KXH31343.1 - 1.2e-38 133.4 0.1 1.6e-38 133.1 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family WSC PF01822.19 KXH31344.1 - 1.9e-12 47.2 4.3 1.9e-12 47.2 4.3 3.2 2 1 0 2 2 2 1 WSC domain Macoilin PF09726.9 KXH31345.1 - 4.4 5.7 6.3 6.1 5.3 6.3 1.1 1 0 0 1 1 1 0 Macoilin family Peptidase_M22 PF00814.25 KXH31346.1 - 0.047 13.4 1.6 0.06 13.0 0.3 1.8 2 0 0 2 2 2 0 Glycoprotease family TMEM100 PF16311.5 KXH31346.1 - 1.9 8.1 7.5 0.21 11.1 2.4 1.9 2 0 0 2 2 2 0 Transmembrane protein 100 DUF2427 PF10348.9 KXH31346.1 - 2.3 8.1 10.5 5.6 6.8 1.7 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF2427) Ribonucleas_3_3 PF14622.6 KXH31348.1 - 4.5e-27 94.7 0.0 9.7e-27 93.7 0.0 1.6 1 1 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 KXH31348.1 - 0.064 13.9 0.0 0.18 12.4 0.0 1.8 1 0 0 1 1 1 0 Ribonuclease III domain HAT_KAT11 PF08214.11 KXH31349.1 - 8.1e-98 327.9 0.0 1.5e-97 327.1 0.0 1.4 1 1 0 1 1 1 1 Histone acetylation protein CoA_transf_3 PF02515.17 KXH31350.1 - 7.7e-51 173.3 0.0 5.9e-49 167.1 0.0 2.2 2 0 0 2 2 2 2 CoA-transferase family III DUF4387 PF14330.6 KXH31350.1 - 1.1e-39 135.0 0.0 2.5e-39 133.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4387) AtuA PF07287.11 KXH31350.1 - 1.3e-20 73.4 0.0 6.8e-20 71.1 0.0 1.9 1 1 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA MFS_1 PF07690.16 KXH31351.1 - 1.2e-28 100.1 38.0 1.2e-28 100.1 38.0 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily TMEM51 PF15345.6 KXH31351.1 - 0.33 10.8 3.7 0.49 10.2 0.0 2.1 2 0 0 2 2 2 0 Transmembrane protein 51 DUF2207 PF09972.9 KXH31351.1 - 0.56 8.9 0.0 0.56 8.9 0.0 3.0 3 1 0 3 3 3 0 Predicted membrane protein (DUF2207) Fungal_trans PF04082.18 KXH31352.1 - 4.2e-21 75.2 0.0 6.3e-21 74.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH31352.1 - 1e-07 31.9 9.1 2.3e-07 30.8 9.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cyclase PF04199.13 KXH31353.1 - 2e-17 63.7 0.0 2.5e-17 63.4 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase Sugar_tr PF00083.24 KXH31354.1 - 1.3e-102 344.0 22.7 1.6e-102 343.7 22.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH31354.1 - 3.4e-25 88.7 40.9 1.7e-21 76.6 27.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2207 PF09972.9 KXH31355.1 - 0.3 9.8 0.0 0.3 9.8 0.0 3.2 1 1 0 2 2 2 0 Predicted membrane protein (DUF2207) HET PF06985.11 KXH31356.1 - 1.6e-31 109.6 0.3 2.6e-31 108.9 0.3 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) 2-Hacid_dh_C PF02826.19 KXH31357.1 - 8.2e-37 126.3 0.0 1.2e-36 125.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KXH31357.1 - 2.6e-08 33.6 0.0 3.7e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KXH31357.1 - 3.9e-06 27.1 0.0 6.2e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase tRNA-synt_1c PF00749.21 KXH31358.1 - 5.9e-104 347.3 0.1 9.8e-104 346.6 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 KXH31358.1 - 3.9e-40 137.5 0.0 7.9e-40 136.6 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA-synt_1e PF01406.19 KXH31358.1 - 0.011 15.1 0.2 0.026 13.9 0.2 1.5 1 1 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain Glyco_hydro_4C PF11975.8 KXH31358.1 - 0.11 12.5 0.1 0.21 11.7 0.1 1.4 1 0 0 1 1 1 0 Family 4 glycosyl hydrolase C-terminal domain Ribosomal_L1 PF00687.21 KXH31359.1 - 1.5e-21 77.0 0.1 2.2e-21 76.6 0.1 1.3 1 1 0 1 1 1 1 Ribosomal protein L1p/L10e family Salt_tol_Pase PF09506.10 KXH31359.1 - 0.036 12.8 0.0 0.056 12.2 0.0 1.2 1 0 0 1 1 1 0 Glucosylglycerol-phosphate phosphatase (Salt_tol_Pase) COG2 PF06148.11 KXH31360.1 - 2.5e-24 85.8 0.0 3.8e-24 85.3 0.0 1.2 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps51 PF08700.11 KXH31360.1 - 0.0079 16.2 0.0 0.023 14.8 0.0 1.8 2 0 0 2 2 2 1 Vps51/Vps67 Spc7 PF08317.11 KXH31360.1 - 0.18 10.7 0.0 0.26 10.1 0.0 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein CENP-B_dimeris PF09026.10 KXH31360.1 - 0.36 11.2 7.2 0.79 10.1 7.2 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Ribosomal_60s PF00428.19 KXH31360.1 - 0.4 11.3 5.4 1 10.0 5.4 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein RNA_pol_3_Rpc31 PF11705.8 KXH31360.1 - 0.43 10.8 8.2 0.59 10.4 8.2 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 NOA36 PF06524.12 KXH31360.1 - 0.65 9.3 5.0 0.93 8.8 5.0 1.2 1 0 0 1 1 1 0 NOA36 protein ANAPC15 PF15243.6 KXH31360.1 - 2.1 8.8 9.2 3.5 8.1 9.2 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 Hap4_Hap_bind PF10297.9 KXH31361.1 - 2.2e-07 30.7 6.7 9.3e-07 28.8 6.7 2.2 1 0 0 1 1 1 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 bZIP_1 PF00170.21 KXH31361.1 - 6.4e-06 26.2 6.9 1.5e-05 25.0 6.8 1.7 1 1 0 1 1 1 1 bZIP transcription factor ISG65-75 PF11727.8 KXH31361.1 - 0.042 13.1 0.5 0.065 12.5 0.5 1.2 1 0 0 1 1 1 0 Invariant surface glycoprotein dsrm PF00035.26 KXH31361.1 - 0.1 13.3 0.0 0.37 11.5 0.0 1.9 1 0 0 1 1 1 0 Double-stranded RNA binding motif RBM39linker PF15519.6 KXH31361.1 - 0.36 11.9 0.0 0.36 11.9 0.0 4.1 3 2 1 4 4 4 0 linker between RRM2 and RRM3 domains in RBM39 protein TPR_MLP1_2 PF07926.12 KXH31361.1 - 2.1 8.4 10.9 22 5.1 10.9 2.1 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein TFIIA PF03153.13 KXH31361.1 - 5.7 6.8 22.7 2.1 8.2 15.1 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Herpes_US12 PF05363.12 KXH31363.1 - 0.39 11.5 3.8 10 6.9 0.4 2.4 2 0 0 2 2 2 0 Herpesvirus US12 family RseA_C PF03873.13 KXH31363.1 - 0.54 10.5 7.6 0.17 12.2 3.9 2.1 2 0 0 2 2 2 0 Anti sigma-E protein RseA, C-terminal domain Aminotran_1_2 PF00155.21 KXH31364.1 - 1.2e-40 139.8 0.0 1.5e-40 139.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 KXH31364.1 - 0.11 11.8 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase Glyco_trans_4_4 PF13579.6 KXH31364.1 - 0.25 11.8 7.5 4.4 7.7 1.2 2.6 2 1 0 2 2 2 0 Glycosyl transferase 4-like domain Glyco_hydro_88 PF07470.13 KXH31365.1 - 2.4e-67 227.4 6.1 3e-67 227.2 6.1 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Bcl-2 PF00452.19 KXH31365.1 - 0.05 14.3 0.1 0.13 13.0 0.1 1.7 1 0 0 1 1 1 0 Apoptosis regulator proteins, Bcl-2 family F-box PF00646.33 KXH31366.1 - 0.00047 20.0 0.2 0.001 18.9 0.2 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KXH31366.1 - 0.0051 16.7 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KXH31366.1 - 0.029 14.8 0.3 11 6.7 0.0 3.9 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) PARP PF00644.20 KXH31367.1 - 4.4e-57 192.8 0.6 1.3e-56 191.3 0.0 2.1 2 1 1 3 3 3 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 KXH31367.1 - 7.7e-45 152.3 0.3 1.7e-44 151.2 0.1 1.7 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.15 KXH31367.1 - 3.5e-22 78.2 0.6 1.2e-21 76.5 0.6 2.0 1 0 0 1 1 1 1 WGR domain PTCB-BRCT PF12738.7 KXH31367.1 - 4e-08 33.1 0.4 9.1e-08 31.9 0.4 1.7 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 KXH31367.1 - 7e-08 32.7 0.1 1.6e-07 31.6 0.1 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Ndc1_Nup PF09531.10 KXH31367.1 - 2.7 6.5 4.9 3.2 6.3 4.9 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup 7tm_3 PF00003.22 KXH31368.1 - 7.1 6.3 15.8 0.18 11.5 1.8 2.5 1 1 0 2 2 2 0 7 transmembrane sweet-taste receptor of 3 GCPR DUF3425 PF11905.8 KXH31369.1 - 2.6e-19 69.4 0.0 4.7e-19 68.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) HSD3 PF15244.6 KXH31369.1 - 0.033 13.7 0.4 0.041 13.4 0.4 1.1 1 0 0 1 1 1 0 Spermatogenesis-associated protein 7, or HSD3 Zn_clus PF00172.18 KXH31370.1 - 4.7e-05 23.4 10.0 8.2e-05 22.6 10.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.25 KXH31371.1 - 2.9e-17 62.8 0.0 2.8e-13 49.8 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXH31371.1 - 1.6e-11 44.3 0.0 4.8e-11 42.7 0.0 1.7 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH31371.1 - 0.051 13.5 0.1 0.24 11.3 0.1 2.0 1 1 0 1 1 1 0 KR domain GDP_Man_Dehyd PF16363.5 KXH31371.1 - 0.064 12.6 0.0 0.12 11.7 0.0 1.6 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase DUF4884 PF16225.5 KXH31371.1 - 0.067 13.3 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4884) NO_synthase PF02898.15 KXH31371.1 - 0.21 10.6 0.1 0.97 8.4 0.0 1.8 2 0 0 2 2 2 0 Nitric oxide synthase, oxygenase domain ADH_zinc_N PF00107.26 KXH31372.1 - 2.4e-10 40.5 0.0 3.9e-09 36.6 0.0 2.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXH31372.1 - 0.00062 19.6 0.0 0.0012 18.7 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain bPH_2 PF03703.14 KXH31372.1 - 0.15 12.3 0.0 0.52 10.5 0.0 1.9 2 0 0 2 2 2 0 Bacterial PH domain Stig1 PF04885.13 KXH31373.1 - 1.7e-10 41.5 79.4 9.3e-07 29.4 36.3 3.5 1 1 2 3 3 3 2 Stigma-specific protein, Stig1 E1-E2_ATPase PF00122.20 KXH31375.1 - 4.4e-34 117.6 22.2 7.9e-30 103.7 0.5 4.0 5 0 0 5 5 5 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 KXH31375.1 - 9.5e-30 103.6 5.5 9.5e-30 103.6 5.5 2.3 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KXH31375.1 - 1.9e-21 77.3 0.7 4.8e-17 63.0 0.6 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KXH31375.1 - 2.3e-20 72.5 0.0 5e-20 71.4 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KXH31375.1 - 1.7e-14 53.2 0.0 4e-14 52.0 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KXH31375.1 - 1.7e-06 28.0 0.6 0.00021 21.1 0.6 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Lactamase_B PF00753.27 KXH31376.1 - 2.6e-06 27.6 0.1 4.9e-06 26.7 0.1 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KXH31376.1 - 0.00014 21.5 0.0 0.00028 20.5 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain MFS_1 PF07690.16 KXH31377.1 - 5.6e-43 147.2 40.6 3.1e-36 125.1 26.0 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3035 PF11233.8 KXH31377.1 - 0.029 14.7 0.0 0.055 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3035) PAP2 PF01569.21 KXH31378.1 - 9.8e-26 90.1 4.2 9.8e-26 90.1 4.2 1.6 2 0 0 2 2 2 1 PAP2 superfamily DUF983 PF06170.12 KXH31378.1 - 5.1 7.6 6.5 39 4.8 3.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF983) SRP54 PF00448.22 KXH31379.1 - 2e-75 252.7 3.0 2.9e-75 252.2 1.6 1.9 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 KXH31379.1 - 2.2e-30 105.2 6.2 2.2e-30 105.2 6.2 4.0 3 2 2 5 5 4 1 Signal peptide binding domain SRP54_N PF02881.19 KXH31379.1 - 8.6e-16 57.9 0.2 2.7e-14 53.1 0.2 2.7 1 1 0 1 1 1 1 SRP54-type protein, helical bundle domain AAA_33 PF13671.6 KXH31379.1 - 4.1e-06 27.0 0.0 9.6e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain cobW PF02492.19 KXH31379.1 - 7.1e-06 25.7 0.9 4.7e-05 23.0 1.0 2.2 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.6 KXH31379.1 - 4.3e-05 24.0 0.1 4.3e-05 24.0 0.1 2.3 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.6 KXH31379.1 - 0.00015 22.2 0.0 0.00038 20.9 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.23 KXH31379.1 - 0.0017 18.4 0.4 0.07 13.2 0.1 3.3 3 1 0 3 3 3 1 50S ribosome-binding GTPase AAA_30 PF13604.6 KXH31379.1 - 0.0018 18.0 0.0 0.0054 16.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KXH31379.1 - 0.0023 17.3 0.0 0.0055 16.0 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin APS_kinase PF01583.20 KXH31379.1 - 0.0029 17.5 0.0 0.0056 16.6 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase Thymidylate_kin PF02223.17 KXH31379.1 - 0.006 16.3 0.4 0.018 14.7 0.0 2.0 2 0 0 2 2 2 1 Thymidylate kinase AAA_22 PF13401.6 KXH31379.1 - 0.0068 16.7 0.0 0.018 15.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 KXH31379.1 - 0.0073 16.3 0.3 0.017 15.1 0.3 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit CbiA PF01656.23 KXH31379.1 - 0.0077 16.3 0.0 0.019 15.0 0.0 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_18 PF13238.6 KXH31379.1 - 0.008 16.7 0.0 0.019 15.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain SRPRB PF09439.10 KXH31379.1 - 0.0094 15.4 0.6 2.8 7.3 0.8 3.2 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.17 KXH31379.1 - 0.012 15.4 0.3 0.041 13.6 0.1 2.0 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein MobB PF03205.14 KXH31379.1 - 0.023 14.6 0.4 0.057 13.3 0.0 1.9 2 0 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.6 KXH31379.1 - 0.025 14.8 0.0 0.046 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KXH31379.1 - 0.045 14.1 0.1 0.1 12.9 0.1 1.6 1 0 0 1 1 1 0 AAA domain 6PF2K PF01591.18 KXH31379.1 - 0.085 12.1 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase Arf PF00025.21 KXH31379.1 - 0.11 12.0 0.2 0.4 10.1 0.0 2.0 3 0 0 3 3 3 0 ADP-ribosylation factor family AAA PF00004.29 KXH31379.1 - 0.12 12.8 0.2 0.36 11.3 0.2 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SKA2 PF16740.5 KXH31379.1 - 0.66 9.8 4.2 9.7 6.0 1.6 2.6 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 Peptidase_M14 PF00246.24 KXH31380.1 - 6.4e-27 95.1 0.6 9e-27 94.6 0.6 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase p450 PF00067.22 KXH31381.1 - 6.4e-51 173.5 0.0 1.6e-50 172.2 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 7tm_2 PF00002.24 KXH31489.1 - 1.3e-12 47.5 5.4 1.3e-12 47.5 5.4 1.7 2 0 0 2 2 2 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.11 KXH31489.1 - 2.4e-11 43.3 5.0 2.4e-11 43.3 5.0 1.9 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor 7tm_1 PF00001.21 KXH31489.1 - 2.1e-07 30.6 3.7 2.9e-07 30.1 3.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Git3 PF11710.8 KXH31489.1 - 2.4e-06 27.5 7.8 5.2e-06 26.4 7.8 1.6 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Frizzled PF01534.17 KXH31489.1 - 0.029 13.4 13.0 0.29 10.1 9.8 2.4 2 1 0 2 2 2 0 Frizzled/Smoothened family membrane region TMEMspv1-c74-12 PF11044.8 KXH31489.1 - 0.12 12.4 0.2 0.28 11.2 0.2 1.5 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein STE3 PF02076.15 KXH31489.1 - 0.15 11.3 13.3 0.0064 15.8 4.8 2.7 2 2 1 3 3 3 0 Pheromone A receptor 7TM_GPCR_Srsx PF10320.9 KXH31489.1 - 0.57 9.5 12.0 0.0067 15.8 3.7 1.9 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srsx Ribonuclease_T2 PF00445.18 KXH31491.1 - 5.5e-17 62.6 0.0 7.9e-17 62.1 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease T2 family Zn_clus PF00172.18 KXH31492.1 - 1.5e-10 41.1 10.4 2.3e-10 40.4 10.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXH31492.1 - 1.4e-07 30.8 3.1 4.4e-07 29.2 2.7 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain TFIIA PF03153.13 KXH31492.1 - 2.7 7.9 17.5 5.9 6.8 17.5 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Clr5 PF14420.6 KXH31493.1 - 8.8e-16 57.9 0.7 2e-15 56.7 0.7 1.7 1 0 0 1 1 1 1 Clr5 domain AAA_8 PF12780.7 KXH31493.1 - 0.11 11.8 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region D4 TPR_4 PF07721.14 KXH31493.1 - 1.2 10.0 5.3 0.73 10.6 0.5 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Amidase PF01425.21 KXH31495.1 - 1.5e-36 126.3 2.8 3.6e-26 92.2 2.9 3.4 2 1 1 3 3 3 3 Amidase Paramyxo_ncap PF00973.19 KXH31495.1 - 0.026 13.4 0.1 0.034 13.1 0.1 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein DivIC PF04977.15 KXH31495.1 - 0.054 13.3 1.8 0.86 9.4 0.0 2.5 2 1 0 2 2 2 0 Septum formation initiator DUF2235 PF09994.9 KXH31496.1 - 4.2e-85 285.6 5.8 1.1e-83 281.0 5.8 2.7 1 1 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) DUF3328 PF11807.8 KXH31497.1 - 7e-54 182.9 0.9 8.5e-54 182.6 0.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) fn3 PF00041.21 KXH31498.1 - 1.2e-15 57.6 5.5 4.2e-05 23.8 0.0 3.3 3 0 0 3 3 3 3 Fibronectin type III domain Lipase_GDSL_2 PF13472.6 KXH31498.1 - 1.6e-13 51.5 0.0 2.6e-11 44.2 0.0 2.5 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KXH31498.1 - 4.6e-05 23.5 0.0 0.00011 22.3 0.0 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DUF4992 PF16383.5 KXH31498.1 - 0.007 15.9 0.7 0.93 9.0 0.1 2.5 2 0 0 2 2 2 2 Domain of unknown function ChitinaseA_N PF08329.10 KXH31498.1 - 0.011 15.4 0.9 0.19 11.4 0.1 2.6 2 1 0 3 3 3 0 Chitinase A, N-terminal domain Lipase_GDSL_3 PF14606.6 KXH31498.1 - 0.19 11.8 0.0 0.37 10.9 0.0 1.5 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family HET PF06985.11 KXH31499.1 - 2.2e-24 86.5 0.0 3.4e-24 85.8 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Fungal_trans PF04082.18 KXH31500.1 - 2.2e-09 36.8 0.1 6.4e-09 35.2 0.1 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH31500.1 - 4.3e-07 29.9 14.0 9e-07 28.9 14.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ATP-synt_D PF01813.17 KXH31500.1 - 0.055 13.3 0.1 0.18 11.6 0.1 1.8 1 1 0 1 1 1 0 ATP synthase subunit D ANAPC5 PF12862.7 KXH31500.1 - 0.14 12.2 1.1 5.6 7.1 0.3 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 5 FAD_binding_3 PF01494.19 KXH31501.1 - 7.3e-19 68.2 0.1 1.4e-18 67.3 0.1 1.3 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KXH31501.1 - 0.0089 15.3 0.3 0.27 10.5 0.0 2.8 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase ADH_zinc_N PF00107.26 KXH31502.1 - 2.4e-26 92.2 0.2 4.5e-26 91.4 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXH31502.1 - 2.4e-16 61.0 0.0 7.1e-16 59.5 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXH31502.1 - 5.6e-06 26.2 0.0 2e-05 24.4 0.0 2.0 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 KXH31502.1 - 0.00036 20.4 0.0 0.00094 19.1 0.0 1.7 1 1 0 1 1 1 1 N-terminal domain of oxidoreductase AlaDh_PNT_C PF01262.21 KXH31502.1 - 0.00081 18.7 0.1 0.0012 18.1 0.1 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain DuoxA PF10204.9 KXH31502.1 - 0.084 11.9 0.1 0.15 11.0 0.1 1.3 1 0 0 1 1 1 0 Dual oxidase maturation factor ELFV_dehydrog PF00208.21 KXH31502.1 - 0.094 12.4 0.1 0.16 11.7 0.1 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 2-Hacid_dh_C PF02826.19 KXH31502.1 - 0.11 11.9 0.1 0.2 11.0 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Propeptide_C1 PF08127.13 KXH31502.1 - 0.17 11.8 0.3 1.7 8.6 0.2 2.4 2 0 0 2 2 2 0 Peptidase family C1 propeptide NACHT PF05729.12 KXH31503.1 - 0.00013 21.9 0.7 0.0041 17.1 0.7 2.6 1 1 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 KXH31503.1 - 0.00049 20.4 0.0 0.0031 17.8 0.0 2.4 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 KXH31503.1 - 0.0019 18.7 0.8 0.0097 16.4 0.0 2.4 2 0 0 2 2 2 1 ABC transporter AAA_18 PF13238.6 KXH31503.1 - 0.0038 17.8 0.0 0.014 16.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 KXH31503.1 - 0.011 15.6 0.0 0.033 14.1 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 KXH31503.1 - 0.021 14.5 0.0 0.049 13.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Helo_like_N PF17111.5 KXH31503.1 - 0.025 13.9 1.5 0.061 12.7 1.5 1.7 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins PIF1 PF05970.14 KXH31503.1 - 0.045 12.9 0.0 0.086 12.0 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase AAA_30 PF13604.6 KXH31503.1 - 0.048 13.4 0.0 0.13 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KXH31503.1 - 0.055 12.6 0.1 0.2 10.8 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain AAA_33 PF13671.6 KXH31503.1 - 0.074 13.2 0.0 0.21 11.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KXH31503.1 - 0.1 13.0 3.3 0.47 10.8 0.0 3.3 3 1 0 3 3 3 0 AAA ATPase domain AAA_23 PF13476.6 KXH31503.1 - 0.2 12.1 0.1 0.2 12.1 0.1 3.0 2 1 0 2 2 1 0 AAA domain APG6_N PF17675.1 KXH31503.1 - 8.8 6.9 7.4 3.1 8.3 3.5 2.3 2 0 0 2 2 2 0 Apg6 coiled-coil region CorA PF01544.18 KXH31504.1 - 6e-11 42.2 1.4 6e-10 38.9 0.0 2.9 3 0 0 3 3 3 1 CorA-like Mg2+ transporter protein Vac_Fusion PF02346.16 KXH31504.1 - 0.14 11.8 1.4 0.49 10.1 0.0 2.6 3 0 0 3 3 3 0 Chordopoxvirus multifunctional envelope protein A27 MFS_1 PF07690.16 KXH31505.1 - 5.3e-17 61.8 48.3 1.1e-09 37.7 27.0 2.5 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.13 KXH31505.1 - 2.4e-10 39.5 15.1 4.9e-10 38.5 15.0 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Thioesterase PF00975.20 KXH31507.1 - 9.4e-11 42.3 0.0 0.00095 19.3 0.0 3.0 2 1 0 2 2 2 2 Thioesterase domain Abhydrolase_6 PF12697.7 KXH31507.1 - 0.0019 18.9 0.3 0.0022 18.6 0.3 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 KXH31507.1 - 0.05 13.4 0.0 0.087 12.6 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 KXH31507.1 - 0.08 12.8 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold p450 PF00067.22 KXH31508.1 - 1.9e-30 106.1 0.0 2.5e-30 105.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Kinesin PF00225.23 KXH31510.1 - 5e-105 351.1 3.2 5e-105 351.1 3.2 2.0 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KXH31510.1 - 3.4e-56 189.3 0.3 9.4e-56 187.9 0.3 1.8 1 0 0 1 1 1 1 Microtubule binding AAA_24 PF13479.6 KXH31510.1 - 0.032 13.9 0.0 0.093 12.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KXH31510.1 - 0.037 14.4 0.0 0.037 14.4 0.0 2.5 2 1 0 2 2 1 0 AAA ATPase domain Filament PF00038.21 KXH31510.1 - 0.073 12.7 43.0 6.7 6.2 43.0 3.4 1 1 0 1 1 1 0 Intermediate filament protein AAA_22 PF13401.6 KXH31510.1 - 0.12 12.6 0.9 0.59 10.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain SHE3 PF17078.5 KXH31510.1 - 0.13 12.0 35.0 0.023 14.4 10.5 2.6 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 WEMBL PF05701.11 KXH31510.1 - 0.32 9.6 40.5 0.012 14.3 33.3 2.0 2 0 0 2 2 2 0 Weak chloroplast movement under blue light Phage_tail_T PF06223.12 KXH31510.1 - 1.1 9.8 4.4 5.9 7.5 0.3 3.0 3 0 0 3 3 2 0 Minor tail protein T DUF148 PF02520.17 KXH31510.1 - 1.4 9.0 11.4 0.16 12.1 1.3 3.4 1 1 2 3 3 3 0 Domain of unknown function DUF148 Uso1_p115_C PF04871.13 KXH31510.1 - 1.8 8.9 43.4 3.3 8.1 19.9 4.8 2 1 3 5 5 5 0 Uso1 / p115 like vesicle tethering protein, C terminal region Spc42p PF11544.8 KXH31510.1 - 2.2 8.3 12.7 0.025 14.6 1.2 3.3 3 0 0 3 3 3 0 Spindle pole body component Spc42p DUF4407 PF14362.6 KXH31510.1 - 4.3 6.6 26.8 7.2 5.9 17.7 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF3584 PF12128.8 KXH31510.1 - 8 3.8 40.4 1.8 6.0 34.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) DUF1664 PF07889.12 KXH31510.1 - 9.8 6.2 18.9 1.2 9.2 3.1 3.8 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) Acyltransferase PF01553.21 KXH31511.1 - 1.3e-05 24.9 0.0 2.3e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase ILVD_EDD PF00920.21 KXH31512.1 - 1.2e-213 710.4 0.1 1.4e-213 710.2 0.1 1.0 1 0 0 1 1 1 1 Dehydratase family CLP_protease PF00574.23 KXH31513.1 - 5.9e-40 137.1 0.1 7.6e-40 136.7 0.1 1.1 1 0 0 1 1 1 1 Clp protease FMO-like PF00743.19 KXH31513.1 - 0.042 12.3 0.2 0.049 12.1 0.2 1.1 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like Tho2 PF11262.8 KXH31513.1 - 0.89 8.7 4.4 1 8.5 4.4 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Dynamin_N PF00350.23 KXH31514.1 - 8.8e-11 42.1 1.1 4.9e-10 39.7 0.0 2.8 2 0 0 2 2 2 1 Dynamin family AAA_16 PF13191.6 KXH31514.1 - 0.00023 21.6 0.0 0.0014 19.1 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain MMR_HSR1 PF01926.23 KXH31514.1 - 0.001 19.1 0.0 0.012 15.7 0.0 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Bombinin PF05298.11 KXH31514.1 - 0.023 14.4 0.0 0.095 12.4 0.0 2.1 1 0 0 1 1 1 0 Bombinin RsgA_GTPase PF03193.16 KXH31514.1 - 0.024 14.5 0.0 0.069 13.0 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase Roc PF08477.13 KXH31514.1 - 0.082 13.1 0.0 0.28 11.4 0.0 1.9 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 KXH31514.1 - 0.24 11.7 0.7 4.7 7.5 0.0 2.9 3 0 0 3 3 3 0 AAA domain Clr5 PF14420.6 KXH31515.1 - 1.1e-22 80.0 0.3 2.7e-22 78.8 0.3 1.7 1 0 0 1 1 1 1 Clr5 domain MFS_1 PF07690.16 KXH31516.1 - 4.1e-29 101.6 20.2 4.1e-29 101.6 20.2 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily TMEM234 PF10639.9 KXH31516.1 - 0.19 11.8 2.2 3.8 7.6 0.6 2.6 2 0 0 2 2 2 0 Putative transmembrane family 234 Gly-zipper_Omp PF13488.6 KXH31516.1 - 0.36 10.9 5.5 12 6.0 0.1 2.9 2 0 0 2 2 2 0 Glycine zipper MBOAT PF03062.19 KXH31517.1 - 8.8e-35 120.7 19.5 9.1e-34 117.3 19.5 2.1 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Pex14_N PF04695.13 KXH31517.1 - 0.03 15.0 0.1 2.9 8.5 0.0 2.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region GH131_N PF18271.1 KXH31520.1 - 1.4e-81 274.0 0.7 1.7e-81 273.7 0.7 1.1 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain MFS_1 PF07690.16 KXH31521.1 - 4.4e-32 111.4 54.9 3.4e-31 108.4 53.0 2.9 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF2208 PF09973.9 KXH31521.1 - 1.9 8.1 5.5 3.8 7.0 5.5 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2208) GWT1 PF06423.12 KXH31521.1 - 2.6 8.2 5.7 56 3.8 0.0 3.1 3 0 0 3 3 3 0 GWT1 ADH_zinc_N PF00107.26 KXH31522.1 - 4.5e-05 23.4 0.0 9.8e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXH31522.1 - 0.013 16.6 0.0 0.045 14.8 0.0 1.9 1 1 1 2 2 2 0 Zinc-binding dehydrogenase CMD PF02627.20 KXH31523.1 - 2.8e-05 24.1 0.0 0.007 16.4 0.0 2.5 1 1 1 3 3 3 2 Carboxymuconolactone decarboxylase family Glyco_hydro_28 PF00295.17 KXH31524.1 - 1.4e-46 159.1 0.9 1.8e-46 158.7 0.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 adh_short PF00106.25 KXH31526.1 - 1.3e-30 106.3 0.0 1.7e-30 106.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXH31526.1 - 6e-20 71.8 0.0 1.1e-19 70.9 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH31526.1 - 2.7e-12 47.0 0.0 3.6e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KXH31526.1 - 0.00048 19.4 0.0 0.00058 19.1 0.0 1.3 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Glyco_tran_WecB PF03808.13 KXH31526.1 - 0.0044 17.0 0.0 0.0082 16.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase WecB/TagA/CpsF family Eno-Rase_NADH_b PF12242.8 KXH31526.1 - 0.15 11.8 0.0 0.32 10.8 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Zn_clus PF00172.18 KXH31527.1 - 1.7e-07 31.3 12.5 3.9e-07 30.1 12.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Coatomer_WDAD PF04053.14 KXH31528.1 - 2.9e-174 580.3 0.0 1e-173 578.5 0.0 1.8 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.32 KXH31528.1 - 7e-40 134.3 5.8 4.4e-06 27.3 0.0 8.7 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXH31528.1 - 5.1e-08 33.1 0.1 2.8 8.3 0.0 6.1 4 2 1 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KXH31528.1 - 3.4e-05 22.7 2.0 0.032 12.9 0.0 3.9 2 2 2 4 4 4 3 Nucleoporin Nup120/160 BBS2_Mid PF14783.6 KXH31528.1 - 0.0032 17.5 0.1 1.1 9.4 0.0 3.5 2 2 1 3 3 3 1 Ciliary BBSome complex subunit 2, middle region Mannitol_dh_C PF08125.13 KXH31529.1 - 2.3e-39 135.3 0.0 3.6e-39 134.7 0.0 1.3 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.23 KXH31529.1 - 2e-18 67.0 0.0 5.6e-18 65.5 0.0 1.8 1 0 0 1 1 1 1 Mannitol dehydrogenase Rossmann domain UDPG_MGDP_dh_N PF03721.14 KXH31529.1 - 0.0049 16.5 0.4 0.015 14.9 0.1 1.9 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.16 KXH31529.1 - 0.005 16.5 0.2 0.64 9.6 0.0 3.2 3 1 0 3 3 3 1 Ketopantoate reductase PanE/ApbA Sacchrp_dh_NADP PF03435.18 KXH31529.1 - 0.016 15.4 0.4 1.1 9.5 0.1 2.7 3 0 0 3 3 3 0 Saccharopine dehydrogenase NADP binding domain RuBisCO_small PF00101.20 KXH31529.1 - 0.17 11.9 0.0 0.34 10.9 0.0 1.5 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase, small chain RRM_1 PF00076.22 KXH31531.1 - 3.7e-17 61.9 0.0 6.1e-17 61.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.11 KXH31531.1 - 0.15 11.8 0.2 0.29 10.8 0.2 1.4 1 0 0 1 1 1 0 Ribonuclease B OB domain Glyco_hydro_15 PF00723.21 KXH31532.1 - 6.2e-48 163.7 0.0 1.1e-45 156.2 0.0 2.2 1 1 0 1 1 1 1 Glycosyl hydrolases family 15 TPT PF03151.16 KXH31533.1 - 6.2e-20 71.7 13.8 8.2e-20 71.3 13.8 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KXH31533.1 - 2.7e-05 24.4 34.8 0.0065 16.6 8.3 2.5 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 KXH31533.1 - 0.0044 16.3 15.1 0.0044 16.3 15.1 1.8 2 0 0 2 2 2 1 UAA transporter family PUNUT PF16913.5 KXH31533.1 - 0.0094 15.2 15.3 0.023 13.9 15.3 1.7 1 1 0 1 1 1 1 Purine nucleobase transmembrane transport Dehydrin PF00257.19 KXH31533.1 - 0.13 12.8 0.0 0.13 12.8 0.0 3.2 2 1 0 3 3 3 0 Dehydrin SHOCT PF09851.9 KXH31533.1 - 0.15 11.8 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 Short C-terminal domain SLATT_1 PF18181.1 KXH31533.1 - 3.3 7.7 4.2 4.7 7.2 0.4 2.5 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 DUF5549 PF17703.1 KXH31534.1 - 0.5 10.0 8.8 0.59 9.8 8.8 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5549) Zfx_Zfy_act PF04704.13 KXH31534.1 - 2.3 7.3 6.5 3.1 6.8 6.5 1.1 1 0 0 1 1 1 0 Zfx / Zfy transcription activation region Dsh_C PF12316.8 KXH31534.1 - 4.2 7.7 14.1 5.2 7.4 14.1 1.1 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Presenilin PF01080.17 KXH31534.1 - 7.7 5.2 6.4 8.2 5.1 6.4 1.0 1 0 0 1 1 1 0 Presenilin FXMRP1_C_core PF12235.8 KXH31534.1 - 9.4 6.9 18.0 18 6.0 18.0 1.5 1 1 0 1 1 1 0 Fragile X-related 1 protein core C terminal Peptidase_S9 PF00326.21 KXH31535.1 - 1.6e-53 181.3 0.0 2.8e-53 180.5 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family PD40 PF07676.12 KXH31535.1 - 0.00025 20.9 0.0 0.034 14.1 0.0 2.7 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat NuA4 PF09340.10 KXH31536.1 - 3.5e-24 84.5 1.3 5.8e-24 83.8 0.0 1.8 2 0 0 2 2 2 1 Histone acetyltransferase subunit NuA4 NUDE_C PF04880.13 KXH31536.1 - 2 8.8 9.0 4.5 7.7 8.8 1.7 1 1 0 1 1 1 0 NUDE protein, C-terminal conserved region Alpha-amylase PF00128.24 KXH31538.1 - 7.4e-55 186.8 0.0 1e-54 186.4 0.0 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.11 KXH31538.1 - 2.1e-19 69.6 0.0 3.5e-19 68.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) Glyco_hydro_70 PF02324.16 KXH31538.1 - 0.19 9.9 0.1 0.25 9.5 0.1 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 70 Fungal_trans PF04082.18 KXH31539.1 - 1.1e-15 57.3 0.1 2.6e-15 56.2 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_18 PF00704.28 KXH31541.1 - 1e-86 291.5 5.9 1.2e-86 291.2 5.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Ilm1 PF10311.9 KXH31542.1 - 0.022 14.4 0.7 0.031 13.9 0.7 1.3 1 0 0 1 1 1 0 Increased loss of mitochondrial DNA protein 1 DUF3087 PF11286.8 KXH31542.1 - 0.09 12.2 0.5 0.19 11.2 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3087) DHHC PF01529.20 KXH31542.1 - 10 6.3 6.6 4.2 7.5 4.3 1.6 2 0 0 2 2 2 0 DHHC palmitoyltransferase LRR_6 PF13516.6 KXH31543.1 - 2.4e-08 33.4 5.3 0.28 11.4 0.0 6.3 7 0 0 7 7 7 2 Leucine Rich repeat LRR_4 PF12799.7 KXH31543.1 - 5e-08 33.1 17.9 0.039 14.4 0.2 5.5 6 1 0 6 6 6 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KXH31543.1 - 0.0011 19.2 0.4 14 6.7 0.1 5.3 5 0 0 5 5 5 1 Leucine Rich Repeat LRR_8 PF13855.6 KXH31543.1 - 0.0013 18.4 9.7 1.7 8.5 0.2 5.0 4 1 0 4 4 4 2 Leucine rich repeat Radial_spoke PF04712.12 KXH31543.1 - 3.6 6.4 13.3 39 3.0 12.6 2.1 2 0 0 2 2 2 0 Radial spokehead-like protein zf-H2C2_2 PF13465.6 KXH31544.1 - 5.2e-06 26.6 1.3 5.2e-06 26.6 1.3 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.6 KXH31544.1 - 5.3e-06 26.3 0.7 0.011 15.7 0.0 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger FOXP-CC PF16159.5 KXH31544.1 - 8.8e-06 26.3 6.7 0.25 12.0 0.0 3.6 2 1 1 3 3 3 2 FOXP coiled-coil domain zf-C2H2 PF00096.26 KXH31544.1 - 9.7e-06 25.8 0.5 9.7e-06 25.8 0.5 3.8 3 1 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXH31544.1 - 0.00092 19.9 8.2 0.0039 17.9 0.4 3.3 3 0 0 3 3 3 1 C2H2-type zinc finger DUF5595 PF18077.1 KXH31544.1 - 0.0088 16.1 0.4 0.025 14.7 0.4 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF5595) zf-H2C2_5 PF13909.6 KXH31544.1 - 0.27 11.1 2.8 0.62 9.9 0.1 2.4 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 KXH31544.1 - 0.6 10.5 4.0 2.6 8.5 0.3 3.1 3 1 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Sina PF03145.16 KXH31544.1 - 8.5 6.3 11.4 3.7 7.4 1.0 3.0 2 1 2 4 4 4 0 Seven in absentia protein family Fe_hyd_lg_C PF02906.14 KXH31546.1 - 2.3e-48 165.0 0.0 6.2e-48 163.6 0.0 1.7 1 1 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain SUZ PF12752.7 KXH31547.1 - 2.9e-05 24.7 5.0 2.9e-05 24.7 5.0 3.0 2 1 0 2 2 2 1 SUZ domain DUF1754 PF08555.10 KXH31547.1 - 0.042 14.6 1.8 4.1 8.3 0.6 2.4 2 0 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) U1snRNP70_N PF12220.8 KXH31547.1 - 0.47 11.1 5.9 0.11 13.2 1.2 2.0 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal API5 PF05918.11 KXH31547.1 - 0.75 8.5 4.5 1.1 8.0 4.5 1.3 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Glyco_hydro_3_C PF01915.22 KXH31588.1 - 1.7e-64 217.6 0.0 2.8e-64 216.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KXH31588.1 - 9.1e-38 130.4 0.0 1.4e-37 129.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KXH31588.1 - 2.9e-25 88.2 0.7 8.3e-25 86.7 0.3 2.0 2 0 0 2 2 2 1 Fibronectin type III-like domain PA14 PF07691.12 KXH31588.1 - 6.7e-19 68.1 0.0 1.6e-18 67.0 0.0 1.7 1 0 0 1 1 1 1 PA14 domain Lipase_GDSL_2 PF13472.6 KXH31588.1 - 0.055 13.9 0.0 0.13 12.6 0.0 1.6 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family CARDB PF07705.11 KXH31588.1 - 0.063 13.5 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 CARDB DUF2306 PF10067.9 KXH31589.1 - 5.3e-14 52.6 15.1 5.9e-14 52.5 10.1 2.2 2 0 0 2 2 2 1 Predicted membrane protein (DUF2306) DUF420 PF04238.12 KXH31589.1 - 0.028 14.7 2.6 0.028 14.7 2.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF420) S1FA PF04689.13 KXH31589.1 - 7.8 6.7 7.0 47 4.2 3.0 3.4 2 1 1 3 3 3 0 DNA binding protein S1FA FTA4 PF13093.6 KXH31590.1 - 5.6e-63 212.5 0.6 6.6e-63 212.2 0.6 1.1 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Peptidase_C2 PF00648.21 KXH31591.1 - 6.1e-63 212.6 1.1 1.1e-61 208.5 1.1 2.2 1 1 0 1 1 1 1 Calpain family cysteine protease DUF724 PF05266.14 KXH31591.1 - 0.88 9.4 11.3 2.5 7.9 11.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF724) tRNA-synt_1c PF00749.21 KXH31591.1 - 3 6.7 9.1 5.3 5.8 9.1 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), catalytic domain zf-CCHC PF00098.23 KXH31592.1 - 5.2e-23 80.0 24.3 3.2e-08 33.3 2.5 3.5 4 0 0 4 4 4 3 Zinc knuckle zf-CCHC_5 PF14787.6 KXH31592.1 - 2.5e-06 27.1 13.7 0.0036 17.0 1.0 3.3 1 1 2 3 3 3 3 GAG-polyprotein viral zinc-finger zf-CCHC_3 PF13917.6 KXH31592.1 - 0.00071 19.5 14.0 0.088 12.8 0.8 3.2 2 1 1 3 3 3 3 Zinc knuckle zf-CCHC_4 PF14392.6 KXH31592.1 - 0.00087 19.0 11.4 0.24 11.1 0.7 3.2 3 0 0 3 3 3 3 Zinc knuckle zf-CCHC_6 PF15288.6 KXH31592.1 - 0.042 13.7 0.3 0.042 13.7 0.3 3.5 4 0 0 4 4 4 0 Zinc knuckle C1_1 PF00130.22 KXH31592.1 - 1.6 8.6 11.2 6.5 6.7 5.9 2.2 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_4 PF16866.5 KXH31592.1 - 2.6 8.2 8.7 19 5.4 0.3 2.2 1 1 1 2 2 2 0 PHD-finger WD40 PF00400.32 KXH31594.1 - 1e-36 124.3 5.3 2.6e-07 31.2 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXH31594.1 - 4.5e-13 49.3 0.1 0.00017 21.8 0.0 4.4 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KXH31594.1 - 0.0033 16.8 0.0 5.6 6.2 0.0 3.0 2 1 0 3 3 3 2 WD40-like domain Nucleoporin_N PF08801.11 KXH31594.1 - 0.0086 14.9 0.6 2.6 6.7 0.1 3.1 1 1 1 2 2 2 2 Nup133 N terminal like Nup160 PF11715.8 KXH31594.1 - 0.086 11.5 0.3 15 4.1 0.0 3.0 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KXH31594.1 - 0.12 11.3 0.0 4.5 6.1 0.0 2.8 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein TRAPP PF04051.16 KXH31595.1 - 1.1e-35 122.4 0.1 1.4e-35 122.2 0.1 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component PNGaseA PF12222.8 KXH31595.1 - 0.043 12.7 0.0 0.047 12.5 0.0 1.1 1 0 0 1 1 1 0 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A DUF4250 PF14056.6 KXH31595.1 - 0.083 12.9 0.1 0.17 11.9 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4250) adh_short PF00106.25 KXH31621.1 - 9e-46 155.8 0.2 1.2e-45 155.4 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXH31621.1 - 8.5e-40 136.8 0.3 1e-39 136.5 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH31621.1 - 1.5e-06 28.3 1.5 5.5e-06 26.4 0.4 2.2 2 1 0 2 2 2 1 KR domain HHH_5 PF14520.6 KXH31621.1 - 0.079 13.6 0.1 0.27 11.9 0.0 1.9 2 0 0 2 2 2 0 Helix-hairpin-helix domain Lactamase_B PF00753.27 KXH31622.1 - 2.8e-07 30.7 0.2 1.3e-06 28.6 0.1 2.2 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily FAD_oxidored PF12831.7 KXH31623.1 - 1.1e-66 226.0 0.0 1.1e-65 222.7 0.0 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KXH31623.1 - 1e-06 28.2 1.7 2.1e-06 27.1 1.7 1.5 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 KXH31623.1 - 2.7e-06 26.7 0.3 3.9e-06 26.2 0.3 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A DAO PF01266.24 KXH31623.1 - 2.7e-06 27.2 0.2 5.1e-06 26.3 0.2 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXH31623.1 - 2.7e-05 24.3 0.3 0.0001 22.4 0.3 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXH31623.1 - 6.2e-05 22.4 0.1 9e-05 21.8 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXH31623.1 - 0.00013 22.5 0.3 0.00029 21.3 0.3 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KXH31623.1 - 0.0092 15.3 0.4 0.016 14.5 0.4 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Trp_halogenase PF04820.14 KXH31623.1 - 0.033 13.1 0.2 0.96 8.2 0.1 2.1 2 0 0 2 2 2 0 Tryptophan halogenase HI0933_like PF03486.14 KXH31623.1 - 0.034 12.9 0.5 0.05 12.3 0.5 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.6 KXH31623.1 - 0.11 11.7 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Fungal_trans PF04082.18 KXH31624.1 - 6.2e-09 35.3 0.4 6.2e-09 35.3 0.4 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH31624.1 - 5.2e-05 23.3 5.5 9e-05 22.5 5.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ceramidase PF05875.12 KXH31624.1 - 0.26 10.7 4.1 3.6 6.9 0.3 2.2 2 0 0 2 2 2 0 Ceramidase NmrA PF05368.13 KXH31625.1 - 1.5e-33 116.3 0.0 2e-33 115.9 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXH31625.1 - 2e-09 37.6 0.1 3.1e-09 37.0 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KXH31625.1 - 0.00013 21.6 0.2 0.00025 20.6 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXH31625.1 - 0.038 13.0 0.0 0.051 12.6 0.0 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 KXH31625.1 - 0.061 12.8 0.1 0.12 11.8 0.1 1.5 1 0 0 1 1 1 0 short chain dehydrogenase TrkA_N PF02254.18 KXH31625.1 - 0.2 11.9 0.0 0.36 11.1 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain GalKase_gal_bdg PF10509.9 KXH31626.1 - 1.4e-19 69.4 0.1 2.6e-19 68.5 0.1 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.26 KXH31626.1 - 4.3e-15 55.7 2.0 1.1e-14 54.3 2.0 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KXH31626.1 - 4.6e-13 49.4 0.0 1.6e-12 47.6 0.0 2.0 1 0 0 1 1 1 1 GHMP kinases C terminal HTH_23 PF13384.6 KXH31626.1 - 0.039 13.7 0.1 0.23 11.3 0.0 2.2 2 0 0 2 2 2 0 Homeodomain-like domain Sigma70_r4_2 PF08281.12 KXH31626.1 - 0.11 12.1 0.0 0.32 10.7 0.0 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_3 PF01381.22 KXH31626.1 - 0.12 12.4 0.0 0.37 10.9 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix Asp PF00026.23 KXH31627.1 - 9.9e-33 113.9 0.2 1.6e-32 113.2 0.2 1.3 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 KXH31627.1 - 0.0033 17.2 0.0 0.0096 15.7 0.0 1.8 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal TAXi_N PF14543.6 KXH31627.1 - 0.0073 16.6 0.1 0.014 15.6 0.1 1.5 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Metallothio PF00131.20 KXH31632.1 - 0.0071 16.5 16.1 0.0071 16.5 16.1 1.0 1 0 0 1 1 1 1 Metallothionein NAD_binding_8 PF13450.6 KXH31634.1 - 2.3e-10 40.5 1.3 3.5e-10 39.9 0.2 1.9 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KXH31634.1 - 6.7e-09 35.3 2.5 1.3e-08 34.4 2.5 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KXH31634.1 - 9e-08 31.9 1.5 1.4e-07 31.2 1.5 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 KXH31634.1 - 9.3e-07 28.7 0.9 2.1e-06 27.6 0.9 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 KXH31634.1 - 5.9e-06 25.8 0.1 0.00033 20.1 0.1 2.1 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase HI0933_like PF03486.14 KXH31634.1 - 9.5e-06 24.6 0.6 1.5e-05 23.9 0.6 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.14 KXH31634.1 - 3.9e-05 23.0 0.0 0.00015 21.1 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KXH31634.1 - 8.3e-05 22.0 0.4 0.00014 21.2 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 KXH31634.1 - 0.00063 20.2 0.6 0.0013 19.2 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXH31634.1 - 0.0016 17.7 0.1 0.0038 16.5 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KXH31634.1 - 0.0022 17.1 0.8 0.0036 16.4 0.8 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.17 KXH31634.1 - 0.007 15.6 0.3 0.013 14.7 0.3 1.4 1 0 0 1 1 1 1 Thi4 family AlaDh_PNT_C PF01262.21 KXH31634.1 - 0.053 12.8 0.3 0.1 11.9 0.3 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Trp_halogenase PF04820.14 KXH31634.1 - 0.058 12.2 1.1 0.11 11.3 1.1 1.4 1 0 0 1 1 1 0 Tryptophan halogenase Lycopene_cycl PF05834.12 KXH31634.1 - 0.058 12.4 0.0 0.084 11.9 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein IlvN PF07991.12 KXH31634.1 - 0.11 12.1 0.3 0.23 11.0 0.3 1.5 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Glyco_hydro_39 PF01229.17 KXH31635.1 - 0.031 12.9 0.2 0.044 12.4 0.2 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 39 DUF3112 PF11309.8 KXH31636.1 - 1.2e-09 37.9 16.0 5.3e-09 35.8 0.8 2.6 2 1 0 3 3 3 2 Protein of unknown function (DUF3112) Glyco_hydro_16 PF00722.21 KXH31638.1 - 3.1e-41 140.8 4.1 5.3e-41 140.0 4.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 STOP PF05217.12 KXH31638.1 - 0.2 12.0 1.7 0.3 11.4 0.3 1.9 2 0 0 2 2 2 0 STOP protein EF-hand_7 PF13499.6 KXH31645.1 - 2.1e-10 40.9 0.0 8e-08 32.6 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KXH31645.1 - 6.2e-09 34.8 0.0 0.036 13.6 0.0 3.3 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 KXH31645.1 - 8.5e-07 28.4 0.0 0.14 12.2 0.0 3.4 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 KXH31645.1 - 7.3e-05 22.5 0.0 0.00016 21.4 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_4 PF12763.7 KXH31645.1 - 0.00051 20.0 0.0 0.029 14.3 0.0 2.1 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand Phage_ABA_S PF18066.1 KXH31645.1 - 0.061 14.0 0.0 1.1 9.9 0.0 2.2 2 0 0 2 2 2 0 Phage ABA sandwich domain ParA PF10609.9 KXH31646.1 - 8.7e-96 320.1 0.1 1e-95 319.9 0.1 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 KXH31646.1 - 9.3e-11 41.9 0.0 2.6e-10 40.5 0.0 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 KXH31646.1 - 1.6e-09 37.9 0.7 3.4e-07 30.4 0.1 2.1 1 1 0 2 2 2 2 AAA domain ArsA_ATPase PF02374.15 KXH31646.1 - 7.2e-05 22.1 0.1 0.0024 17.1 0.0 2.6 2 1 1 3 3 3 1 Anion-transporting ATPase MipZ PF09140.11 KXH31646.1 - 0.00015 21.1 0.0 0.00019 20.8 0.0 1.2 1 0 0 1 1 1 1 ATPase MipZ Fer4_NifH PF00142.18 KXH31646.1 - 0.0011 18.4 0.0 0.09 12.2 0.0 2.3 2 1 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family CBP_BcsQ PF06564.12 KXH31646.1 - 0.0025 17.3 0.2 0.024 14.1 0.1 2.0 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsQ AAA_26 PF13500.6 KXH31646.1 - 0.0051 16.7 0.5 0.24 11.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KXH31646.1 - 0.037 13.6 0.7 0.072 12.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 KXH31646.1 - 0.16 10.9 0.1 0.31 10.0 0.1 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB CLP1_P PF16575.5 KXH31646.1 - 0.18 11.6 0.0 0.33 10.7 0.0 1.4 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Tudor_3 PF18115.1 KXH31647.1 - 6.8e-07 29.0 0.0 1.2e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain FlxA PF14282.6 KXH31647.1 - 0.0014 18.5 1.2 0.005 16.8 1.2 1.9 1 0 0 1 1 1 1 FlxA-like protein DUF4537 PF15057.6 KXH31647.1 - 0.0085 16.1 0.0 0.017 15.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) IL11 PF07400.11 KXH31647.1 - 0.012 15.3 0.5 0.018 14.7 0.5 1.3 1 0 0 1 1 1 0 Interleukin 11 LBR_tudor PF09465.10 KXH31647.1 - 0.034 14.0 0.0 0.065 13.1 0.0 1.5 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain Alpha-E PF04168.12 KXH31647.1 - 0.075 12.8 0.3 0.1 12.3 0.3 1.1 1 0 0 1 1 1 0 A predicted alpha-helical domain with a conserved ER motif. DUF2894 PF11445.8 KXH31647.1 - 0.089 13.3 7.7 0.79 10.2 1.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2894) TCO89 PF10452.9 KXH31648.1 - 5.5e-06 25.7 0.7 0.00021 20.4 0.1 3.2 3 0 0 3 3 3 2 TORC1 subunit TCO89 HET PF06985.11 KXH31651.1 - 1.9e-13 51.0 0.5 1.5e-09 38.4 0.1 2.4 2 0 0 2 2 2 2 Heterokaryon incompatibility protein (HET) ERp29_N PF07912.13 KXH31651.1 - 0.064 13.4 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 ERp29, N-terminal domain DUF4470 PF14737.6 KXH31652.1 - 1.1e-19 70.5 0.1 2.6e-19 69.2 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) zf-MYND PF01753.18 KXH31652.1 - 1.7e-11 44.0 12.4 3.2e-11 43.1 12.4 1.5 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KXH31652.1 - 1.1 9.6 9.4 2.7 8.4 9.4 1.6 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Apolipoprotein PF01442.18 KXH31654.1 - 0.00075 19.4 2.0 0.001 19.0 2.0 1.3 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain LEA_4 PF02987.16 KXH31654.1 - 0.011 15.8 6.5 0.011 15.8 6.5 2.3 2 1 1 3 3 3 0 Late embryogenesis abundant protein Borrelia_P83 PF05262.11 KXH31654.1 - 0.036 12.6 4.1 0.035 12.6 4.1 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein CsbD PF05532.12 KXH31654.1 - 0.22 11.4 22.4 1.2 9.1 5.9 3.6 2 1 1 3 3 3 0 CsbD-like YtxH PF12732.7 KXH31654.1 - 0.26 11.9 9.7 9.3 6.9 9.7 2.2 1 1 0 1 1 1 0 YtxH-like protein DUF883 PF05957.13 KXH31654.1 - 0.26 11.9 4.1 0.29 11.8 2.0 1.9 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF809 PF05663.11 KXH31654.1 - 1.3 9.1 3.8 1.5 8.9 3.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF809) ECH_1 PF00378.20 KXH31655.1 - 2.4e-39 135.1 0.0 1.6e-34 119.3 0.0 3.1 2 1 0 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXH31655.1 - 8.1e-27 94.6 0.0 4.2e-22 79.1 0.0 2.2 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase Glyco_trans_4_4 PF13579.6 KXH31655.1 - 0.0047 17.4 0.2 0.069 13.6 0.1 2.2 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain MIT PF04212.18 KXH31724.1 - 2.3e-14 53.2 2.7 4.6e-14 52.2 2.7 1.5 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain UCR_14kD PF02271.16 KXH31724.1 - 1.1 9.2 4.5 2.2 8.3 0.0 3.0 3 0 0 3 3 3 0 Ubiquinol-cytochrome C reductase complex 14kD subunit GTP_EFTU PF00009.27 KXH31725.1 - 1.4e-49 168.3 0.1 2.2e-49 167.6 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 KXH31725.1 - 8.4e-43 144.9 3.3 1.5e-42 144.1 3.3 1.4 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 KXH31725.1 - 6.3e-19 67.8 0.0 1.3e-18 66.8 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus MMR_HSR1 PF01926.23 KXH31725.1 - 2.2e-05 24.5 0.1 5.7e-05 23.2 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase EFG_II PF14492.6 KXH31725.1 - 8e-05 22.7 0.0 0.00022 21.2 0.0 1.8 1 1 0 1 1 1 1 Elongation Factor G, domain II Ras PF00071.22 KXH31725.1 - 8.4e-05 22.2 0.0 0.00025 20.7 0.0 1.7 2 0 0 2 2 2 1 Ras family GTP_EFTU_D2 PF03144.25 KXH31725.1 - 0.0003 21.1 0.0 0.0007 19.9 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 KXH31725.1 - 0.0046 16.8 0.0 0.015 15.2 0.0 1.8 2 0 0 2 2 2 1 Class II release factor RF3, C-terminal domain SRPRB PF09439.10 KXH31725.1 - 0.027 13.9 0.0 0.082 12.3 0.0 1.8 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Roc PF08477.13 KXH31725.1 - 0.052 13.8 0.0 0.45 10.8 0.0 2.4 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase His_Phos_1 PF00300.22 KXH31726.1 - 2.1e-12 47.2 0.0 2.8e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) CTNNBL PF08216.11 KXH31727.1 - 6.3e-40 135.5 0.0 4.3e-39 132.9 0.0 2.4 2 0 0 2 2 2 1 Catenin-beta-like, Arm-motif containing nuclear Arm PF00514.23 KXH31727.1 - 0.033 14.2 0.0 2.4 8.3 0.0 3.1 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat TH1 PF04858.13 KXH31727.1 - 0.038 12.6 0.0 0.057 12.0 0.0 1.2 1 0 0 1 1 1 0 TH1 protein V-ATPase_G PF03179.15 KXH31728.1 - 2e-32 111.9 15.9 2.2e-32 111.7 15.9 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit DUF3552 PF12072.8 KXH31728.1 - 0.0058 16.1 11.2 0.0058 16.1 11.2 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF3552) YusW PF14039.6 KXH31728.1 - 0.022 15.3 5.6 0.033 14.7 5.3 1.4 1 1 0 1 1 1 0 YusW-like protein ATP-synt_B PF00430.18 KXH31728.1 - 0.029 14.5 8.3 0.029 14.5 8.3 2.0 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) RRF PF01765.19 KXH31728.1 - 0.055 13.4 11.1 0.067 13.1 11.1 1.2 1 0 0 1 1 1 0 Ribosome recycling factor V-ATPase_G_2 PF16999.5 KXH31728.1 - 0.075 13.5 14.0 0.11 12.9 14.0 1.3 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit SAPS PF04499.15 KXH31728.1 - 0.12 11.1 5.5 0.13 11.0 5.5 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF2203 PF09969.9 KXH31728.1 - 0.17 12.6 5.3 0.22 12.2 5.3 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) ATP11 PF06644.11 KXH31728.1 - 0.36 10.6 8.6 0.43 10.3 8.6 1.0 1 0 0 1 1 1 0 ATP11 protein RNA_pol_Rpb2_6 PF00562.28 KXH31729.1 - 5.4e-125 417.5 0.1 8.5e-125 416.8 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 KXH31729.1 - 4.5e-56 189.6 0.0 1.4e-55 187.9 0.0 1.8 1 1 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 KXH31729.1 - 2.1e-47 161.2 0.0 4.3e-47 160.2 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 KXH31729.1 - 1.2e-33 115.4 0.1 2.7e-33 114.2 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 KXH31729.1 - 2e-25 88.7 0.1 4.9e-25 87.5 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 KXH31729.1 - 4.6e-24 84.8 1.1 1.4e-23 83.2 1.1 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 RNA_pol_Rpb2_4 PF04566.13 KXH31729.1 - 2.7e-20 72.4 3.1 3.1e-20 72.2 1.4 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_45 PF10385.9 KXH31729.1 - 0.2 12.0 0.3 8.3 6.8 0.1 3.0 2 0 0 2 2 2 0 RNA polymerase beta subunit external 1 domain IDO PF01231.18 KXH31730.1 - 3.8e-167 556.5 0.0 4.4e-167 556.3 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase UEV PF05743.13 KXH31731.1 - 3.6e-37 126.9 0.0 7.4e-37 125.9 0.0 1.5 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.10 KXH31731.1 - 6.6e-22 77.2 0.0 1.1e-21 76.5 0.0 1.4 1 0 0 1 1 1 1 Vps23 core domain DUF4653 PF15546.6 KXH31731.1 - 0.008 15.8 2.0 0.015 14.9 2.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4653) UQ_con PF00179.26 KXH31731.1 - 0.016 14.9 0.1 0.028 14.1 0.1 1.4 1 0 0 1 1 1 0 Ubiquitin-conjugating enzyme HCR PF07111.12 KXH31731.1 - 0.018 13.1 1.5 0.029 12.4 1.5 1.2 1 0 0 1 1 1 0 Alpha helical coiled-coil rod protein (HCR) CCDC24 PF15669.5 KXH31731.1 - 0.44 10.4 3.2 0.44 10.4 0.6 2.3 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 24 family IBR PF01485.21 KXH31735.1 - 2.7e-10 40.3 44.4 1.1e-06 28.8 13.1 3.3 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 KXH31735.1 - 0.0088 16.4 7.0 0.0088 16.4 7.0 3.6 3 0 0 3 3 3 1 Ring finger domain zf-RING_11 PF17123.5 KXH31735.1 - 0.024 14.4 0.4 0.024 14.4 0.4 2.8 3 0 0 3 3 3 0 RING-like zinc finger eIF3_subunit PF08597.10 KXH31735.1 - 2.1 8.2 18.9 3.8 7.3 18.9 1.4 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Bul1_N PF04425.12 KXH31735.1 - 3 6.5 10.7 5.4 5.7 10.7 1.4 1 0 0 1 1 1 0 Bul1 N terminus GREB1 PF15782.5 KXH31735.1 - 5.9 3.9 18.9 8.1 3.4 18.9 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Zn_clus PF00172.18 KXH31736.1 - 2e-09 37.4 7.9 2e-09 37.4 7.9 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Lactonase PF10282.9 KXH31737.1 - 4e-85 286.1 0.0 4.8e-85 285.8 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller PEMT PF04191.13 KXH31738.1 - 2.6e-56 188.5 10.3 1.4e-34 118.7 1.7 2.7 2 0 0 2 2 2 2 Phospholipid methyltransferase HECW_N PF16562.5 KXH31738.1 - 0.0047 16.7 0.1 0.016 15.0 0.0 1.8 2 0 0 2 2 2 1 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 SKICH PF17751.1 KXH31738.1 - 0.12 12.9 0.1 1.7 9.2 0.1 2.2 1 1 0 1 1 1 0 SKICH domain DUF863 PF05904.11 KXH31739.1 - 0.0071 14.9 0.0 0.0078 14.7 0.0 1.0 1 0 0 1 1 1 1 Plant protein of unknown function (DUF863) Med30 PF11315.8 KXH31739.1 - 0.14 12.4 2.5 0.18 12.0 2.5 1.1 1 0 0 1 1 1 0 Mediator complex subunit 30 HA2 PF04408.23 KXH31739.1 - 0.7 10.2 5.3 2.3 8.6 0.6 2.1 2 0 0 2 2 2 0 Helicase associated domain (HA2) eIF3g PF12353.8 KXH31740.1 - 2.8e-44 150.5 1.6 5.2e-44 149.6 1.6 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.22 KXH31740.1 - 5.9e-16 58.1 0.1 9.9e-16 57.3 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH_7 PF18586.1 KXH31740.1 - 0.021 15.2 0.2 0.04 14.2 0.2 1.4 1 0 0 1 1 1 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 1 RRM_occluded PF16842.5 KXH31740.1 - 0.033 14.1 0.0 0.078 12.8 0.0 1.6 1 0 0 1 1 1 0 Occluded RNA-recognition motif PH PF00169.29 KXH31741.1 - 0.19 12.3 0.0 0.46 11.0 0.0 1.7 1 1 0 1 1 1 0 PH domain Pox_A_type_inc PF04508.12 KXH31742.1 - 0.0024 17.6 1.1 0.0058 16.4 1.1 1.7 1 0 0 1 1 1 1 Viral A-type inclusion protein repeat JAKMIP_CC3 PF16034.5 KXH31742.1 - 0.011 15.6 0.3 2.4 8.1 0.0 2.2 2 0 0 2 2 2 0 JAKMIP CC3 domain Shugoshin_N PF07558.11 KXH31742.1 - 0.021 14.7 0.1 0.051 13.5 0.1 1.6 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region SlyX PF04102.12 KXH31742.1 - 0.081 13.6 10.1 2.3 8.9 4.9 2.5 2 0 0 2 2 2 0 SlyX PriC PF07445.12 KXH31742.1 - 0.4 10.6 7.6 0.061 13.3 3.8 1.7 2 1 0 2 2 2 0 Primosomal replication protein priC DivIC PF04977.15 KXH31742.1 - 7.2 6.5 7.7 2.8 7.8 0.1 2.3 2 0 0 2 2 2 0 Septum formation initiator DUF3290 PF11694.8 KXH31749.1 - 0.16 12.0 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3290) DUF5373 PF17343.2 KXH31749.1 - 0.18 11.6 0.1 1.9 8.3 0.0 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5373) DUF3176 PF11374.8 KXH31750.1 - 2.4e-26 92.0 4.2 2.4e-26 92.0 4.2 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) SOTI PF17079.5 KXH31750.1 - 0.013 15.9 0.3 0.013 15.9 0.3 1.8 2 0 0 2 2 2 0 Male-specific protein scotti dbPDZ_assoc PF16610.5 KXH31818.1 - 0.0017 18.6 1.6 0.0022 18.2 0.3 1.9 1 1 1 2 2 2 1 Unstructured region between two PDZ domains on Dlg5 PGP_phosphatase PF09419.10 KXH31819.1 - 1.9e-65 219.6 0.0 2.2e-65 219.4 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.6 KXH31819.1 - 6e-05 23.0 0.0 9.8e-05 22.3 0.0 1.5 1 1 0 1 1 1 1 HAD-hyrolase-like MTHFR PF02219.17 KXH31819.1 - 0.001 18.4 0.0 0.0014 18.0 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Hydrolase PF00702.26 KXH31819.1 - 0.018 15.4 0.0 0.022 15.0 0.0 1.1 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Alk_phosphatase PF00245.20 KXH31822.1 - 1.5e-63 215.2 0.1 4.7e-63 213.6 0.1 1.7 1 1 0 1 1 1 1 Alkaline phosphatase Phosphodiest PF01663.22 KXH31822.1 - 1.8e-07 31.1 0.0 3.1e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KXH31822.1 - 3.3e-07 30.0 0.0 5.1e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Sulfatase DUF229 PF02995.17 KXH31822.1 - 0.0001 21.1 0.4 0.00018 20.3 0.2 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF229) DUF1501 PF07394.12 KXH31822.1 - 0.017 14.2 0.1 0.025 13.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) ABC_membrane PF00664.23 KXH31823.1 - 8.1e-88 294.6 37.1 2.5e-44 152.0 15.8 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KXH31823.1 - 1.1e-69 233.2 0.0 2.2e-34 118.9 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KXH31823.1 - 3.6e-15 56.0 0.1 6.7e-05 22.4 0.0 4.2 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KXH31823.1 - 1.4e-08 34.3 0.1 0.0033 17.1 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 KXH31823.1 - 1.6e-07 31.7 0.1 0.0077 16.5 0.0 3.8 3 1 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 KXH31823.1 - 1.6e-07 31.4 0.0 0.015 15.2 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase ABC_ATPase PF09818.9 KXH31823.1 - 2.9e-07 29.6 0.6 0.064 12.0 0.0 3.9 4 0 0 4 4 4 2 Predicted ATPase of the ABC class Zeta_toxin PF06414.12 KXH31823.1 - 3.8e-07 29.6 0.0 0.019 14.3 0.0 3.3 3 0 0 3 3 3 2 Zeta toxin AAA_16 PF13191.6 KXH31823.1 - 1.1e-06 29.2 4.7 0.0005 20.5 0.2 3.6 4 1 0 4 4 2 2 AAA ATPase domain AAA_15 PF13175.6 KXH31823.1 - 1.7e-06 28.0 0.0 0.05 13.3 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.6 KXH31823.1 - 1.2e-05 25.0 0.1 0.24 11.0 0.1 3.0 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KXH31823.1 - 1.5e-05 24.8 3.4 0.033 13.9 0.0 3.8 4 1 0 4 4 3 2 AAA domain AAA_21 PF13304.6 KXH31823.1 - 0.00044 20.2 2.9 1.5 8.6 0.3 4.4 3 1 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system G-alpha PF00503.20 KXH31823.1 - 0.00046 19.5 0.0 0.55 9.3 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit APS_kinase PF01583.20 KXH31823.1 - 0.00054 19.9 0.1 1.3 8.9 0.0 2.9 3 0 0 3 3 2 2 Adenylylsulphate kinase AAA_7 PF12775.7 KXH31823.1 - 0.00062 19.3 0.4 1 8.9 0.0 3.3 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_33 PF13671.6 KXH31823.1 - 0.0022 18.2 0.0 1.3 9.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 KXH31823.1 - 0.0025 18.4 0.0 1.1 9.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KXH31823.1 - 0.0027 17.7 0.3 4.8 7.2 0.0 3.6 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) DUF87 PF01935.17 KXH31823.1 - 0.0028 17.8 1.5 2.8 8.0 0.0 2.8 2 1 0 2 2 2 2 Helicase HerA, central domain Rad17 PF03215.15 KXH31823.1 - 0.0045 16.9 0.0 0.061 13.2 0.0 2.2 2 0 0 2 2 2 1 Rad17 P-loop domain RrnaAD PF00398.20 KXH31823.1 - 0.0057 15.8 0.0 0.022 13.9 0.0 1.8 2 0 0 2 2 2 1 Ribosomal RNA adenine dimethylase AAA PF00004.29 KXH31823.1 - 0.0075 16.7 0.4 15 6.0 0.0 4.0 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) PRK PF00485.18 KXH31823.1 - 0.0084 15.9 0.2 2.9 7.6 0.0 2.8 3 0 0 3 3 2 1 Phosphoribulokinase / Uridine kinase family SbcCD_C PF13558.6 KXH31823.1 - 0.0087 16.3 1.5 5.3 7.4 0.1 3.7 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_24 PF13479.6 KXH31823.1 - 0.011 15.5 0.2 0.87 9.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 KXH31823.1 - 0.031 14.3 0.0 18 5.4 0.0 3.6 4 0 0 4 4 4 0 AAA domain MMR_HSR1 PF01926.23 KXH31823.1 - 0.031 14.4 0.2 5.4 7.1 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase Ploopntkinase3 PF18751.1 KXH31823.1 - 0.048 13.6 0.2 1.8 8.4 0.0 2.4 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 NB-ARC PF00931.22 KXH31823.1 - 0.049 12.8 0.2 2.9 7.0 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain SRP54 PF00448.22 KXH31823.1 - 0.052 13.2 0.5 8.9 5.9 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain ATP-synt_ab PF00006.25 KXH31823.1 - 0.059 13.0 0.0 3.6 7.2 0.0 2.6 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF815 PF05673.13 KXH31823.1 - 0.1 11.7 0.0 6.8 5.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) RNA_helicase PF00910.22 KXH31823.1 - 0.15 12.5 0.2 6.6 7.2 0.0 2.5 2 0 0 2 2 2 0 RNA helicase ATPase PF06745.13 KXH31823.1 - 0.16 11.3 0.9 6.9 5.9 0.1 2.4 2 0 0 2 2 2 0 KaiC AAA_18 PF13238.6 KXH31823.1 - 0.17 12.4 0.0 20 5.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KXH31823.1 - 0.47 10.7 5.1 0.73 10.1 0.0 2.8 3 0 0 3 3 2 0 AAA domain Fungal_trans PF04082.18 KXH31824.1 - 1.1e-08 34.5 0.0 2e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH31824.1 - 2.9e-08 33.7 11.5 2.9e-08 33.7 11.5 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AlaDh_PNT_C PF01262.21 KXH31825.1 - 6.4e-74 247.9 0.1 1e-73 247.2 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 KXH31825.1 - 3.4e-49 166.6 0.1 8.8e-49 165.3 0.0 1.7 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain 2-Hacid_dh_C PF02826.19 KXH31825.1 - 0.00014 21.3 0.0 0.2 11.0 0.0 2.4 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N PF00107.26 KXH31825.1 - 0.0034 17.4 0.2 0.023 14.7 0.1 2.5 3 1 0 3 3 3 1 Zinc-binding dehydrogenase Pyr_redox_2 PF07992.14 KXH31825.1 - 0.0062 15.8 0.1 0.011 15.0 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXH31825.1 - 0.013 15.7 2.8 0.12 12.6 1.0 3.2 3 1 1 4 4 4 0 NAD(P)-binding Rossmann-like domain Fumerase PF05681.14 KXH31825.1 - 0.043 13.3 0.1 0.065 12.7 0.1 1.2 1 0 0 1 1 1 0 Fumarate hydratase (Fumerase) GIDA PF01134.22 KXH31825.1 - 0.11 11.6 0.8 0.16 11.0 0.8 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_binding_2 PF00890.24 KXH31825.1 - 0.17 10.9 2.4 0.25 10.4 1.7 1.6 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.14 KXH31825.1 - 0.19 10.4 0.4 0.73 8.5 0.4 1.8 2 0 0 2 2 2 0 HI0933-like protein PI3_PI4_kinase PF00454.27 KXH31826.1 - 4.2e-44 151.2 0.0 7.9e-44 150.3 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase SNF2_N PF00176.23 KXH31828.1 - 2e-72 243.9 0.1 5.3e-72 242.4 0.0 1.6 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KXH31828.1 - 3.8e-13 49.7 0.0 9.8e-13 48.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.6 KXH31828.1 - 4.3e-08 33.0 2.3 7.4e-08 32.2 2.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KXH31828.1 - 0.0012 18.6 3.1 0.0058 16.5 3.2 2.0 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KXH31828.1 - 0.0095 15.8 1.3 0.032 14.1 1.4 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXH31828.1 - 0.037 14.4 2.3 0.078 13.3 2.3 1.6 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_3 PF13920.6 KXH31828.1 - 0.037 13.9 3.4 0.047 13.6 1.1 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXH31828.1 - 0.35 10.7 2.7 1.5 8.8 0.2 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXH31828.1 - 0.43 10.7 2.4 0.49 10.5 0.0 2.1 2 0 0 2 2 2 0 RING-type zinc-finger PUF PF00806.19 KXH31838.1 - 6.2e-59 192.5 10.8 1.5e-07 30.7 0.0 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat DUF2054 PF10218.9 KXH31838.1 - 0.11 12.6 1.6 1 9.5 0.8 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2054) 4F5 PF04419.14 KXH31839.1 - 9.8e-11 42.4 15.8 9.8e-11 42.4 15.8 2.4 2 1 0 2 2 2 1 4F5 protein family DFRP_C PF16543.5 KXH31839.1 - 1 9.9 8.6 1.7 9.2 8.6 1.4 1 1 0 1 1 1 0 DRG Family Regulatory Proteins, Tma46 Dabb PF07876.12 KXH31843.1 - 2.4e-20 73.0 0.0 2.7e-20 72.8 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain DUF1871 PF08958.10 KXH31843.1 - 0.13 12.6 0.1 1.2 9.5 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1871) DUF3176 PF11374.8 KXH32000.1 - 1.2e-28 99.5 1.9 5.5e-28 97.3 1.9 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF3176) DUF3676 PF12429.8 KXH32001.1 - 0.0013 18.6 2.2 0.0023 17.8 2.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3676) HET PF06985.11 KXH32002.1 - 0.02 15.2 2.4 1.2 9.5 0.2 3.1 1 1 2 3 3 3 0 Heterokaryon incompatibility protein (HET) UFC1 PF08694.11 KXH32002.1 - 0.063 12.9 0.0 0.23 11.1 0.0 1.8 2 0 0 2 2 2 0 Ubiquitin-fold modifier-conjugating enzyme 1 RPEL PF02755.15 KXH32003.1 - 1.9e-22 78.2 1.8 4.6e-11 42.0 0.2 2.4 2 0 0 2 2 2 2 RPEL repeat KAR9 PF08580.10 KXH32004.1 - 1.8 7.0 13.8 2 6.9 13.8 1.0 1 0 0 1 1 1 0 Yeast cortical protein KAR9 PAP1 PF08601.10 KXH32004.1 - 9.8 5.8 12.8 14 5.2 12.8 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 FKBP_C PF00254.28 KXH32005.1 - 9.6e-34 115.6 0.0 1.4e-33 115.1 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Ferritin_2 PF13668.6 KXH32006.1 - 7.4e-17 61.8 0.1 1.3e-16 61.1 0.1 1.4 1 0 0 1 1 1 1 Ferritin-like domain FAD_binding_4 PF01565.23 KXH32007.1 - 9.5e-25 87.0 0.2 1.5e-24 86.3 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.19 KXH32007.1 - 4.6e-08 33.0 0.0 6.6e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain ABM PF03992.16 KXH32008.1 - 2e-05 24.6 0.0 0.00031 20.8 0.0 2.2 2 0 0 2 2 2 1 Antibiotic biosynthesis monooxygenase Melibiase_2 PF16499.5 KXH32010.1 - 3.1e-48 164.4 0.2 6.2e-48 163.4 0.2 1.5 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 KXH32010.1 - 9.4e-12 44.8 1.3 1.9e-11 43.8 1.3 1.6 1 0 0 1 1 1 1 Alpha galactosidase C-terminal beta sandwich domain DUF905 PF06006.12 KXH32010.1 - 0.087 12.8 0.0 0.26 11.3 0.0 1.9 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF905) Aminotran_4 PF01063.19 KXH32011.1 - 3.5e-19 69.5 0.0 5.3e-19 69.0 0.0 1.4 1 1 0 1 1 1 1 Amino-transferase class IV adh_short PF00106.25 KXH32012.1 - 1.5e-41 142.0 0.0 2e-41 141.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXH32012.1 - 2.2e-21 76.5 0.0 3.1e-21 76.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH32012.1 - 3.1e-08 33.7 0.0 4.5e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.20 KXH32012.1 - 1.5e-05 25.0 0.0 3e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 KXH32012.1 - 5e-05 23.8 0.2 9.5e-05 22.9 0.2 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Polysacc_synt_2 PF02719.15 KXH32012.1 - 0.001 18.3 0.1 0.0015 17.7 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KXH32012.1 - 0.0037 16.8 0.0 0.0053 16.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_2 PF03446.15 KXH32012.1 - 0.014 15.6 0.0 0.042 14.0 0.0 1.8 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Sacchrp_dh_NADP PF03435.18 KXH32012.1 - 0.015 15.5 0.1 0.025 14.8 0.1 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain 3HCDH_N PF02737.18 KXH32012.1 - 0.044 13.7 0.3 0.084 12.8 0.1 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 KXH32012.1 - 0.09 12.2 0.1 0.14 11.5 0.1 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase p450 PF00067.22 KXH32013.1 - 3.4e-60 204.1 0.0 4.7e-60 203.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HAD PF12710.7 KXH32014.1 - 0.00042 20.8 0.0 0.00099 19.6 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Glyco_hydro_88 PF07470.13 KXH32015.1 - 8.6e-08 31.6 1.2 1.9e-07 30.5 1.2 1.5 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Fungal_trans PF04082.18 KXH32016.1 - 1.2e-13 50.7 0.0 2.6e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF2264 PF10022.9 KXH32017.1 - 2.6e-135 451.1 0.0 3.1e-135 450.8 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) Redoxin PF08534.10 KXH32018.1 - 5.7e-17 61.8 0.0 9.6e-17 61.1 0.0 1.3 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 KXH32018.1 - 8.2e-11 41.9 0.0 5.7e-08 32.7 0.0 2.7 2 0 0 2 2 2 2 AhpC/TSA family p450 PF00067.22 KXH32019.1 - 8e-58 196.3 0.0 9.9e-58 196.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Goodbye PF17109.5 KXH32020.1 - 1.4e-13 51.3 0.1 1.4e-13 51.3 0.1 2.8 2 0 0 2 2 2 1 fungal STAND N-terminal Goodbye domain AAA_16 PF13191.6 KXH32020.1 - 6.7e-05 23.3 0.1 0.00024 21.5 0.1 2.0 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 KXH32020.1 - 0.00035 20.5 0.0 0.0011 18.9 0.0 1.9 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 KXH32020.1 - 0.00048 20.4 0.1 0.0058 16.9 0.0 2.9 1 1 1 2 2 2 1 AAA domain FYVE PF01363.21 KXH32020.1 - 0.026 14.7 2.3 0.062 13.4 2.3 1.6 1 0 0 1 1 1 0 FYVE zinc finger Acetyltransf_7 PF13508.7 KXH32021.1 - 1.2e-10 41.6 0.0 3.3e-10 40.2 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KXH32021.1 - 1.6e-10 41.0 0.0 4.8e-10 39.5 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXH32021.1 - 8.6e-10 38.9 0.0 2.4e-09 37.5 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 KXH32021.1 - 3.5e-07 30.1 0.0 7e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 KXH32021.1 - 6.1e-06 26.3 0.0 1.4e-05 25.2 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KXH32021.1 - 0.00013 22.0 0.1 0.00032 20.8 0.0 1.7 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase Acetyltransf_13 PF13880.6 KXH32021.1 - 0.067 13.2 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase MFS_1 PF07690.16 KXH32022.1 - 1.2e-26 93.5 31.5 1.2e-26 93.5 31.5 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF1772 PF08592.11 KXH32022.1 - 0.0022 18.3 9.3 0.18 12.2 0.0 3.3 3 1 1 4 4 4 2 Domain of unknown function (DUF1772) Pam17 PF08566.10 KXH32022.1 - 1.5 8.6 7.4 1.5 8.6 0.2 2.9 3 0 0 3 3 3 0 Mitochondrial import protein Pam17 adh_short PF00106.25 KXH32023.1 - 2.4e-42 144.6 6.9 2.9e-42 144.3 6.9 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXH32023.1 - 3.4e-39 134.8 6.7 4.4e-39 134.4 6.7 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH32023.1 - 2.1e-13 50.6 2.8 2.7e-13 50.3 2.8 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXH32023.1 - 0.0039 16.7 2.2 0.019 14.4 2.2 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family YAcAr PF10686.9 KXH32023.1 - 0.026 14.5 0.8 0.18 11.7 0.6 2.5 2 1 1 3 3 3 0 YspA, cpYpsA-related SLOG family F420_oxidored PF03807.17 KXH32023.1 - 0.067 13.8 0.8 0.067 13.8 0.8 1.9 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Sugar_tr PF00083.24 KXH32024.1 - 1.9e-82 277.5 18.2 2.4e-82 277.2 18.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH32024.1 - 1.4e-19 70.3 45.3 1.7e-13 50.3 18.3 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KXH32024.1 - 0.00011 20.8 2.7 0.0002 20.0 2.7 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Gly-zipper_YMGG PF13441.6 KXH32024.1 - 0.18 11.6 5.1 0.056 13.2 1.0 2.4 2 0 0 2 2 2 0 YMGG-like Gly-zipper adh_short_C2 PF13561.6 KXH32025.1 - 2.5e-48 164.7 0.0 4.7e-48 163.8 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXH32025.1 - 4.4e-42 143.8 0.6 1e-41 142.6 0.6 1.6 1 1 0 1 1 1 1 short chain dehydrogenase Fungal_trans_2 PF11951.8 KXH32025.1 - 2.9e-16 59.3 0.8 5.5e-11 41.9 0.4 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain KR PF08659.10 KXH32025.1 - 5.1e-07 29.8 0.1 9.8e-07 28.9 0.1 1.4 1 0 0 1 1 1 1 KR domain F_bP_aldolase PF01116.20 KXH32026.1 - 4.6e-76 256.0 0.0 5.2e-76 255.8 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II CobS PF02654.15 KXH32026.1 - 0.059 13.6 0.0 0.15 12.2 0.0 1.6 2 0 0 2 2 2 0 Cobalamin-5-phosphate synthase SGL PF08450.12 KXH32027.1 - 1.2e-29 103.7 0.0 2.2e-29 102.8 0.0 1.4 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 KXH32027.1 - 0.00021 21.5 0.0 0.00066 19.8 0.0 1.8 2 0 0 2 2 2 1 Arylesterase NHL PF01436.21 KXH32027.1 - 0.00075 19.4 2.0 0.08 13.0 0.0 3.1 3 0 0 3 3 3 1 NHL repeat Str_synth PF03088.16 KXH32027.1 - 0.0022 18.1 0.0 0.0079 16.3 0.0 2.0 1 1 0 1 1 1 1 Strictosidine synthase DUF5074 PF16819.5 KXH32027.1 - 0.034 14.2 0.0 0.44 10.6 0.0 2.6 2 2 1 3 3 3 0 Domain of unknown function (DUF5074) Reg_prop PF07494.11 KXH32027.1 - 0.12 12.6 0.6 4.5 7.8 0.1 3.0 2 0 0 2 2 2 0 Two component regulator propeller OPT PF03169.15 KXH32028.1 - 1.1e-142 476.8 51.5 1.3e-142 476.6 51.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein FMN_dh PF01070.18 KXH32029.1 - 1.7e-84 283.9 0.1 1.4e-48 165.7 0.0 2.0 1 1 1 2 2 2 2 FMN-dependent dehydrogenase IMPDH PF00478.25 KXH32029.1 - 3.2e-05 23.1 0.4 0.00018 20.6 0.4 1.9 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 KXH32029.1 - 0.00017 21.1 0.0 0.00026 20.5 0.0 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase ThiG PF05690.14 KXH32029.1 - 0.013 14.9 0.0 1.9 7.7 0.0 2.2 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG Glu_synthase PF01645.17 KXH32029.1 - 0.013 14.7 0.1 0.033 13.3 0.0 1.5 1 1 0 1 1 1 0 Conserved region in glutamate synthase DHO_dh PF01180.21 KXH32029.1 - 0.027 13.7 0.5 4.5 6.4 0.0 2.4 3 0 0 3 3 3 0 Dihydroorotate dehydrogenase IGPS PF00218.21 KXH32029.1 - 0.066 12.4 0.0 0.19 10.9 0.0 1.7 1 1 0 1 1 1 0 Indole-3-glycerol phosphate synthase SLAM PF06214.11 KXH32029.1 - 0.12 12.4 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Signaling lymphocytic activation molecule (SLAM) protein adh_short_C2 PF13561.6 KXH32030.1 - 1.8e-50 171.7 0.2 2.3e-50 171.3 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXH32030.1 - 3.4e-43 147.4 0.4 4.7e-43 146.9 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXH32030.1 - 8e-06 25.9 0.1 1.3e-05 25.2 0.1 1.4 1 0 0 1 1 1 1 KR domain Aldo_ket_red PF00248.21 KXH32031.1 - 1.1e-43 149.5 0.0 1.5e-43 149.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family FAD_binding_3 PF01494.19 KXH32032.1 - 8.3e-22 77.9 0.0 1.6e-21 77.0 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KXH32032.1 - 2.1e-05 23.9 0.0 3.9e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXH32032.1 - 6e-05 23.2 0.1 0.00018 21.7 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 KXH32032.1 - 0.00031 20.0 0.0 0.0014 17.8 0.0 1.8 2 0 0 2 2 2 1 Glucose inhibited division protein A DAO PF01266.24 KXH32032.1 - 0.00048 19.8 0.0 0.0021 17.7 0.1 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KXH32032.1 - 0.0014 17.4 0.0 0.0021 16.8 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein AlaDh_PNT_C PF01262.21 KXH32032.1 - 0.0032 16.8 0.0 0.005 16.2 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 KXH32032.1 - 0.0059 17.1 0.0 0.03 14.9 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 KXH32032.1 - 0.0074 16.2 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SE PF08491.10 KXH32032.1 - 0.0091 15.1 0.0 0.018 14.1 0.0 1.4 1 0 0 1 1 1 1 Squalene epoxidase FAD_oxidored PF12831.7 KXH32032.1 - 0.032 13.6 0.3 0.032 13.6 0.3 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KXH32032.1 - 0.078 12.0 0.1 0.27 10.3 0.0 1.9 2 0 0 2 2 2 0 FAD binding domain Peptidase_M24 PF00557.24 KXH32033.1 - 2.7e-48 164.5 0.0 3.2e-48 164.2 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 KXH32033.1 - 7.3e-21 74.2 5.9 7.3e-21 74.2 5.9 1.8 2 0 0 2 2 2 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 KXH32033.1 - 0.00018 21.5 1.3 0.00018 21.5 1.3 1.9 2 0 0 2 2 2 1 MYND finger Cornichon PF03311.14 KXH32034.1 - 3.2e-50 169.5 12.5 3.7e-50 169.3 12.5 1.0 1 0 0 1 1 1 1 Cornichon protein WD40 PF00400.32 KXH32035.1 - 5.4e-32 109.3 9.1 3.5e-06 27.6 0.0 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXH32035.1 - 1.6e-14 53.9 0.1 1.1e-05 25.6 0.0 4.1 2 2 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KXH32035.1 - 0.00078 18.5 0.5 2 7.3 0.0 3.3 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KXH32035.1 - 0.0065 16.4 0.3 1 9.2 0.0 2.9 2 1 2 4 4 4 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KXH32035.1 - 0.067 11.8 0.7 1.7 7.2 0.0 2.6 1 1 2 3 3 3 0 Nucleoporin Nup120/160 DUF1664 PF07889.12 KXH32036.1 - 0.053 13.6 2.9 0.12 12.4 2.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Arginase PF00491.21 KXH32037.1 - 1.7e-80 270.5 0.0 2.2e-80 270.2 0.0 1.1 1 0 0 1 1 1 1 Arginase family DUF3176 PF11374.8 KXH32038.1 - 1.5e-16 60.6 0.1 3.2e-16 59.4 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) Fungal_trans PF04082.18 KXH32039.1 - 3.7e-14 52.4 0.3 5.2e-14 51.9 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH32039.1 - 2.7e-05 24.2 8.3 5.1e-05 23.3 8.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ELYS PF13934.6 KXH32039.1 - 0.12 12.3 0.1 0.26 11.2 0.1 1.5 1 0 0 1 1 1 0 Nuclear pore complex assembly GTP_EFTU PF00009.27 KXH32040.1 - 3.9e-59 199.5 0.4 6.7e-59 198.7 0.4 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 KXH32040.1 - 8e-33 112.4 0.0 1.7e-32 111.4 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.18 KXH32040.1 - 1.8e-31 108.5 0.0 3.6e-31 107.5 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 KXH32040.1 - 1.2e-22 79.7 0.0 2.6e-22 78.7 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KXH32040.1 - 6.1e-14 52.2 0.0 1.4e-13 51.0 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 KXH32040.1 - 1.3e-07 31.5 0.0 3.1e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain DUF442 PF04273.13 KXH32040.1 - 0.035 14.2 0.1 1.5 8.9 0.0 3.2 3 0 0 3 3 3 0 Putative phosphatase (DUF442) MMR_HSR1 PF01926.23 KXH32040.1 - 0.089 12.9 0.1 0.21 11.7 0.1 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF3328 PF11807.8 KXH32041.1 - 6.8e-21 75.0 0.0 9.7e-21 74.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) MFS_1 PF07690.16 KXH32042.1 - 6.7e-26 91.0 59.1 4e-21 75.3 35.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily FMN_red PF03358.15 KXH32044.1 - 1.6e-07 31.2 0.0 2.1e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_1 PF00258.25 KXH32044.1 - 4e-05 23.9 0.1 0.011 15.9 0.1 2.2 1 1 1 2 2 2 2 Flavodoxin Flavodoxin_2 PF02525.17 KXH32044.1 - 4.2e-05 23.3 0.0 5.2e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_5 PF12724.7 KXH32044.1 - 0.0013 18.9 0.0 0.029 14.6 0.0 2.1 1 1 1 2 2 2 1 Flavodoxin domain Methyltransf_22 PF13383.6 KXH32045.1 - 1.8e-18 67.0 0.0 2.4e-18 66.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.12 KXH32045.1 - 7.8e-08 32.5 0.0 1e-07 32.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase FkbM domain BTRD1 PF17660.1 KXH32045.1 - 0.037 13.9 0.0 0.11 12.3 0.0 1.8 2 0 0 2 2 2 0 Bacterial tandem repeat domain 1 DUF4282 PF14110.6 KXH32047.1 - 0.09 13.5 0.2 0.09 13.5 0.2 3.1 1 1 3 4 4 4 0 Domain of unknown function (DUF4282) MFS_1 PF07690.16 KXH32048.1 - 4.8e-21 75.1 33.8 4.8e-21 75.1 33.8 2.6 1 1 2 3 3 3 2 Major Facilitator Superfamily OATP PF03137.20 KXH32048.1 - 0.19 9.9 5.2 2.1 6.6 4.5 2.7 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Tir_receptor_C PF07489.11 KXH32048.1 - 1.4 8.8 5.5 9.1 6.2 0.0 2.9 3 0 0 3 3 3 0 Translocated intimin receptor (Tir) C-terminus SET PF00856.28 KXH32051.1 - 2.7e-07 31.1 0.0 1.4e-06 28.8 0.0 2.0 1 1 0 1 1 1 1 SET domain LAT PF15234.6 KXH32051.1 - 0.29 10.8 1.3 0.47 10.1 1.3 1.2 1 0 0 1 1 1 0 Linker for activation of T-cells Iso_dh PF00180.20 KXH32052.1 - 4.1e-98 328.7 0.0 7.2e-98 327.9 0.0 1.3 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase CHASE3 PF05227.13 KXH32052.1 - 0.021 14.7 0.3 0.051 13.5 0.4 1.5 1 1 0 1 1 1 0 CHASE3 domain Ribosomal_S8 PF00410.19 KXH32054.1 - 1.7e-12 47.3 0.0 1.8e-11 44.1 0.0 2.0 1 1 0 1 1 1 1 Ribosomal protein S8 CR6_interact PF10147.9 KXH32056.1 - 0.0032 17.2 2.1 0.0069 16.1 2.1 1.6 1 0 0 1 1 1 1 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 RCR PF12273.8 KXH32056.1 - 0.015 15.9 0.2 0.015 15.9 0.2 2.8 2 2 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red SARAF PF06682.12 KXH32056.1 - 0.041 13.5 1.2 0.32 10.6 0.0 2.4 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis EphA2_TM PF14575.6 KXH32056.1 - 0.15 13.0 0.0 0.42 11.5 0.0 1.9 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4834 PF16118.5 KXH32056.1 - 0.51 11.3 0.1 0.51 11.3 0.1 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) DUF4519 PF15012.6 KXH32056.1 - 1.5 9.0 6.1 0.43 10.8 0.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) Aminotran_1_2 PF00155.21 KXH32057.1 - 7.4e-37 127.4 0.0 1.5e-36 126.3 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 KXH32057.1 - 4.9e-08 32.2 0.0 6.4e-08 31.8 0.0 1.1 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase Beta_elim_lyase PF01212.21 KXH32057.1 - 8.4e-05 22.0 0.0 0.00015 21.1 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 KXH32057.1 - 0.0001 21.0 0.0 0.00016 20.4 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 KXH32057.1 - 0.00026 20.1 0.0 0.00048 19.2 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KXH32057.1 - 0.2 10.9 0.0 0.27 10.5 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family ABC2_membrane PF01061.24 KXH32058.1 - 5.7e-39 133.7 19.7 1.2e-38 132.6 19.7 1.6 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 KXH32058.1 - 9e-25 87.8 0.0 2e-24 86.6 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 KXH32058.1 - 1.8e-07 30.6 24.4 1.8e-07 30.6 24.4 2.3 2 1 1 3 3 3 1 ABC-2 family transporter protein AAA_21 PF13304.6 KXH32058.1 - 4.5e-05 23.4 0.0 0.25 11.1 0.1 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KXH32058.1 - 0.0045 16.7 0.0 0.01 15.5 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.6 KXH32058.1 - 0.0091 15.6 0.0 0.022 14.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 KXH32058.1 - 0.012 15.5 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_18 PF13238.6 KXH32058.1 - 0.014 15.9 0.0 0.029 14.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 KXH32058.1 - 0.033 13.6 0.0 0.29 10.5 0.0 2.2 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain NACHT PF05729.12 KXH32058.1 - 0.055 13.4 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_22 PF13401.6 KXH32058.1 - 0.077 13.3 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KXH32058.1 - 0.084 13.2 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 KXH32058.1 - 0.093 13.2 0.0 0.21 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain NGP1NT PF08153.12 KXH32060.1 - 2.2e-50 170.2 0.1 3.7e-50 169.4 0.1 1.4 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 KXH32060.1 - 6.2e-18 64.9 0.0 6.9e-14 51.9 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 KXH32060.1 - 5e-06 26.1 0.1 2.5e-05 23.9 0.1 1.9 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KXH32060.1 - 2.9e-05 24.0 0.0 8.4e-05 22.5 0.0 1.8 2 1 0 2 2 2 1 RsgA GTPase Arf PF00025.21 KXH32060.1 - 0.001 18.5 0.0 0.17 11.3 0.0 2.2 2 0 0 2 2 2 2 ADP-ribosylation factor family GTP_EFTU PF00009.27 KXH32060.1 - 0.0027 17.3 0.0 0.25 10.9 0.0 2.8 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 KXH32060.1 - 0.056 13.8 0.0 0.15 12.4 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain Roc PF08477.13 KXH32060.1 - 0.065 13.4 0.0 2.7 8.2 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 KXH32060.1 - 0.067 13.2 0.1 3.5 7.7 0.1 3.0 2 1 1 3 3 3 0 Dynamin family CAP_N PF01213.19 KXH32066.1 - 1.2e-104 350.3 16.1 1.2e-104 350.3 16.1 1.9 1 1 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 KXH32066.1 - 5.5e-56 188.5 5.5 7.5e-56 188.1 5.5 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal Carn_acyltransf PF00755.20 KXH32067.1 - 1.9e-198 660.9 0.0 2.1e-198 660.7 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase SWIRM PF04433.17 KXH32068.1 - 3.6e-31 107.3 0.1 7.5e-31 106.3 0.1 1.6 1 0 0 1 1 1 1 SWIRM domain SWIRM-assoc_1 PF16495.5 KXH32068.1 - 9.7e-30 102.4 4.7 2.1e-29 101.3 4.7 1.6 1 0 0 1 1 1 1 SWIRM-associated region 1 Myb_DNA-binding PF00249.31 KXH32068.1 - 2.6e-10 40.3 0.0 5.8e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KXH32068.1 - 8.4e-06 25.9 0.0 1.8e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.17 KXH32068.1 - 0.0063 16.3 3.4 0.013 15.3 3.4 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type DUF3439 PF11921.8 KXH32068.1 - 0.098 12.6 0.9 0.2 11.6 0.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SANT_DAMP1_like PF16282.5 KXH32068.1 - 0.11 12.7 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 ETF PF01012.21 KXH32069.1 - 5.3e-44 150.3 1.2 9e-44 149.5 1.2 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 KXH32069.1 - 5e-34 116.2 0.5 1.6e-33 114.6 0.5 1.9 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain Pyr_redox_2 PF07992.14 KXH32070.1 - 1.6e-08 34.1 0.1 1.2e-06 28.0 0.0 2.8 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Asp_Glu_race PF01177.22 KXH32070.1 - 0.15 11.9 0.0 0.24 11.2 0.0 1.2 1 0 0 1 1 1 0 Asp/Glu/Hydantoin racemase MutL_C PF08676.11 KXH32072.1 - 6.8e-21 74.6 0.0 1.5e-20 73.5 0.0 1.6 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 KXH32072.1 - 7.6e-20 70.8 0.0 2e-19 69.4 0.0 1.7 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 KXH32072.1 - 1.1e-11 44.6 0.1 3.1e-11 43.3 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KXH32072.1 - 2.6e-06 27.9 0.1 9.6e-06 26.1 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CDC45 PF02724.14 KXH32072.1 - 0.0021 16.4 1.9 0.0021 16.4 1.9 2.2 2 0 0 2 2 2 1 CDC45-like protein PGAP1 PF07819.13 KXH32073.1 - 2.2e-93 312.3 0.0 3.2e-93 311.7 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_1 PF00561.20 KXH32073.1 - 0.0072 16.0 0.0 0.018 14.7 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXH32073.1 - 0.0083 16.8 1.5 0.017 15.8 0.1 2.3 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXH32073.1 - 0.017 14.4 0.0 0.036 13.3 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Palm_thioest PF02089.15 KXH32073.1 - 0.041 13.7 0.0 0.065 13.1 0.0 1.3 1 0 0 1 1 1 0 Palmitoyl protein thioesterase DUF676 PF05057.14 KXH32073.1 - 0.08 12.4 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) UPF0060 PF02694.15 KXH32073.1 - 0.38 11.0 0.0 0.38 11.0 0.0 3.0 3 0 0 3 3 3 0 Uncharacterised BCR, YnfA/UPF0060 family MFS_1 PF07690.16 KXH32074.1 - 2.6e-18 66.1 34.5 4.9e-16 58.6 10.8 3.0 2 1 0 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.13 KXH32074.1 - 7.4e-15 55.1 4.2 7.4e-15 55.1 4.2 1.9 2 0 0 2 2 2 1 Nodulin-like Serinc PF03348.15 KXH32075.1 - 6e-163 542.7 6.9 6.8e-163 542.6 6.9 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) Cys_Met_Meta_PP PF01053.20 KXH32076.1 - 8.1e-139 462.4 0.0 9.4e-139 462.2 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KXH32076.1 - 4e-07 29.6 0.0 9.3e-07 28.3 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KXH32076.1 - 5.5e-06 25.6 0.1 1.6e-05 24.0 0.0 1.7 2 0 0 2 2 2 1 Aminotransferase class-V Met_gamma_lyase PF06838.11 KXH32076.1 - 8.2e-05 21.3 0.3 0.00028 19.6 0.3 1.7 1 1 0 1 1 1 1 Methionine gamma-lyase DegT_DnrJ_EryC1 PF01041.17 KXH32076.1 - 0.00026 20.4 0.1 0.00098 18.5 0.0 1.8 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family PELOTA_1 PF15608.6 KXH32076.1 - 0.022 14.6 0.8 0.12 12.2 1.0 2.0 1 1 1 2 2 2 0 PELOTA RNA binding domain AAA PF00004.29 KXH32077.1 - 4.1e-38 130.8 0.0 7.7e-38 129.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KXH32077.1 - 1.7e-07 30.9 0.0 3.5e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 KXH32077.1 - 4.7e-06 26.4 0.0 1.6e-05 24.7 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KXH32077.1 - 6.7e-06 26.6 0.1 0.00038 20.9 0.0 2.6 1 1 1 2 2 2 1 AAA ATPase domain AAA_14 PF13173.6 KXH32077.1 - 1.5e-05 25.1 0.0 2.8e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KXH32077.1 - 3.4e-05 23.9 0.1 0.00028 20.9 0.1 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KXH32077.1 - 3.8e-05 24.0 0.1 0.0049 17.1 0.0 3.0 1 1 2 3 3 3 1 AAA domain AAA_2 PF07724.14 KXH32077.1 - 7.5e-05 22.9 0.0 0.00013 22.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) TniB PF05621.11 KXH32077.1 - 0.00042 19.8 0.0 0.77 9.1 0.0 2.7 2 1 0 3 3 2 2 Bacterial TniB protein Mg_chelatase PF01078.21 KXH32077.1 - 0.0018 17.7 0.1 0.0038 16.6 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 KXH32077.1 - 0.0037 17.4 0.0 0.0067 16.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 KXH32077.1 - 0.0043 17.4 0.0 0.013 15.9 0.0 1.9 2 0 0 2 2 1 1 RNA helicase AAA_25 PF13481.6 KXH32077.1 - 0.0047 16.5 0.1 0.07 12.7 0.1 2.4 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 KXH32077.1 - 0.0056 16.4 0.0 0.0097 15.7 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein DUF815 PF05673.13 KXH32077.1 - 0.0072 15.5 0.0 0.013 14.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) NACHT PF05729.12 KXH32077.1 - 0.01 15.8 0.0 0.021 14.7 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_18 PF13238.6 KXH32077.1 - 0.011 16.2 0.0 0.039 14.5 0.0 2.0 2 0 0 2 2 1 0 AAA domain Sigma54_activat PF00158.26 KXH32077.1 - 0.015 15.0 0.0 0.035 13.8 0.0 1.6 2 0 0 2 2 1 0 Sigma-54 interaction domain AAA_24 PF13479.6 KXH32077.1 - 0.023 14.4 0.0 0.037 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KXH32077.1 - 0.023 13.9 0.0 0.16 11.1 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain ATPase_2 PF01637.18 KXH32077.1 - 0.024 14.6 0.0 0.15 12.0 0.0 2.1 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea Sigma54_activ_2 PF14532.6 KXH32077.1 - 0.026 14.6 0.0 0.067 13.3 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain TOM6p PF15184.6 KXH32077.1 - 0.027 14.2 0.2 0.057 13.2 0.2 1.5 1 0 0 1 1 1 0 Mitochondrial import receptor subunit TOM6 homolog Rad17 PF03215.15 KXH32077.1 - 0.035 14.0 0.0 0.11 12.4 0.0 1.6 1 1 1 2 2 2 0 Rad17 P-loop domain AAA_28 PF13521.6 KXH32077.1 - 0.035 14.3 0.2 0.11 12.7 0.0 1.9 3 0 0 3 3 1 0 AAA domain TIP49 PF06068.13 KXH32077.1 - 0.057 12.6 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain Zeta_toxin PF06414.12 KXH32077.1 - 0.065 12.5 0.2 0.14 11.4 0.0 1.6 2 0 0 2 2 1 0 Zeta toxin Guanylate_kin PF00625.21 KXH32077.1 - 0.065 12.9 0.1 0.48 10.1 0.0 2.4 2 1 0 2 2 2 0 Guanylate kinase AAA_7 PF12775.7 KXH32077.1 - 0.068 12.7 0.0 0.13 11.8 0.0 1.4 1 1 0 1 1 1 0 P-loop containing dynein motor region TsaE PF02367.17 KXH32077.1 - 0.1 12.6 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 KXH32077.1 - 0.11 13.0 0.0 0.22 12.0 0.0 1.7 1 1 0 1 1 1 0 ABC transporter AAA_17 PF13207.6 KXH32077.1 - 0.11 12.9 0.1 0.33 11.4 0.1 1.8 1 0 0 1 1 1 0 AAA domain Bac_DnaA PF00308.18 KXH32077.1 - 0.12 12.2 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein Parvo_NS1 PF01057.17 KXH32077.1 - 0.12 11.4 0.0 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Csm1 PF12539.8 KXH32078.1 - 8.9e-33 112.8 0.0 1.6e-32 111.9 0.0 1.5 1 0 0 1 1 1 1 Chromosome segregation protein Csm1/Pcs1 Macoilin PF09726.9 KXH32078.1 - 0.00014 20.6 19.4 0.00018 20.2 19.4 1.1 1 0 0 1 1 1 1 Macoilin family UPF0242 PF06785.11 KXH32078.1 - 0.0003 20.9 2.4 0.0003 20.9 2.4 1.8 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0242) N-terminus V_ATPase_I PF01496.19 KXH32078.1 - 0.0054 14.7 0.7 0.0054 14.7 0.7 1.8 2 0 0 2 2 2 1 V-type ATPase 116kDa subunit family Sulfatase_C PF14707.6 KXH32078.1 - 0.0065 17.2 0.3 0.017 15.9 0.3 1.6 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase TACC_C PF05010.14 KXH32078.1 - 0.03 14.1 8.3 0.077 12.8 8.3 1.6 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal GAS PF13851.6 KXH32078.1 - 0.14 11.5 10.0 0.87 8.9 9.6 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Atg14 PF10186.9 KXH32078.1 - 0.18 10.9 6.7 0.35 9.9 6.7 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 PilO PF04350.13 KXH32078.1 - 0.39 10.8 4.3 0.59 10.3 3.4 1.7 1 1 0 1 1 1 0 Pilus assembly protein, PilO BST2 PF16716.5 KXH32078.1 - 0.61 10.7 10.6 0.29 11.7 7.5 2.1 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 FTA4 PF13093.6 KXH32078.1 - 0.93 9.3 8.0 4.5 7.1 7.7 2.1 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 PigN PF04987.14 KXH32079.1 - 2.4e-162 540.9 35.1 2.4e-162 540.9 35.1 1.7 2 0 0 2 2 2 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.22 KXH32079.1 - 4.2e-08 33.2 4.6 1.7e-06 27.9 4.6 2.1 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KXH32079.1 - 2.2e-07 30.6 0.1 3.5e-07 29.9 0.1 1.3 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.18 KXH32079.1 - 7.5e-05 22.2 0.0 0.00012 21.6 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Fungal_trans_2 PF11951.8 KXH32082.1 - 1.2e-08 34.2 0.0 2.2e-07 30.0 0.0 2.0 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH32083.1 - 1.6e-08 34.5 7.0 2.7e-08 33.8 7.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_3_C PF01915.22 KXH32084.1 - 2.8e-53 180.9 0.0 4.8e-53 180.2 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KXH32084.1 - 7e-46 157.1 0.0 1.1e-45 156.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KXH32084.1 - 5e-10 39.3 0.0 1.1e-09 38.2 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 KXH32084.1 - 1.6e-07 31.2 0.0 2.8e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 PA14 domain Fungal_trans PF04082.18 KXH32085.1 - 0.00048 19.3 0.0 0.0011 18.1 0.0 1.6 1 1 1 2 2 2 1 Fungal specific transcription factor domain Methyltransf_23 PF13489.6 KXH32123.1 - 7.7e-20 71.4 0.0 1.2e-19 70.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH32123.1 - 1.8e-10 40.8 0.0 1e-09 38.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH32123.1 - 7.7e-10 39.4 0.0 2.2e-09 37.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH32123.1 - 3.6e-07 30.8 0.0 1.5e-06 28.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH32123.1 - 7.8e-07 29.7 0.0 1.7e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 KXH32123.1 - 0.00098 18.5 0.0 0.0016 17.8 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain FtsJ PF01728.19 KXH32123.1 - 0.004 17.3 0.0 0.0065 16.6 0.0 1.6 1 1 0 1 1 1 1 FtsJ-like methyltransferase Ubie_methyltran PF01209.18 KXH32123.1 - 0.0055 16.1 0.0 0.022 14.1 0.0 2.0 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 KXH32123.1 - 0.0064 16.0 0.0 0.015 14.8 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase PCMT PF01135.19 KXH32123.1 - 0.008 15.9 0.0 0.036 13.8 0.0 2.0 2 1 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 KXH32123.1 - 0.018 14.6 0.0 0.049 13.2 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase small domain Cupin_5 PF06172.11 KXH32124.1 - 6.4e-43 146.3 0.0 7.7e-43 146.0 0.0 1.1 1 0 0 1 1 1 1 Cupin superfamily (DUF985) Peptidase_M48 PF01435.18 KXH32125.1 - 5.9e-37 127.3 0.0 9e-37 126.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 Cyt-b5 PF00173.28 KXH32126.1 - 6.5e-18 64.7 0.1 2e-09 37.5 0.0 2.2 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Kinesin PF00225.23 KXH32127.1 - 1.3e-106 356.4 0.8 3.2e-106 355.0 0.0 1.9 2 0 0 2 2 2 1 Kinesin motor domain DUF3694 PF12473.8 KXH32127.1 - 1.3e-51 175.3 0.0 4.4e-51 173.6 0.0 2.0 1 0 0 1 1 1 1 Kinesin protein Kinesin_assoc PF16183.5 KXH32127.1 - 5.9e-37 127.5 12.2 3.2e-31 108.9 0.2 3.6 2 1 1 3 3 3 2 Kinesin-associated Microtub_bd PF16796.5 KXH32127.1 - 2.1e-21 76.4 0.0 5.4e-21 75.1 0.0 1.7 1 0 0 1 1 1 1 Microtubule binding KIF1B PF12423.8 KXH32127.1 - 1.3e-06 28.8 0.2 1.3e-06 28.8 0.2 2.8 2 0 0 2 2 2 1 Kinesin protein 1B PH PF00169.29 KXH32127.1 - 0.017 15.6 0.0 0.19 12.3 0.0 2.4 1 1 0 1 1 1 0 PH domain Succ_DH_flav_C PF02910.20 KXH32127.1 - 0.045 13.7 1.2 0.19 11.7 1.2 2.1 1 0 0 1 1 1 0 Fumarate reductase flavoprotein C-term Yop-YscD_cpl PF16697.5 KXH32127.1 - 0.082 13.2 0.0 0.43 10.9 0.0 2.3 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain Exonuc_VII_L PF02601.15 KXH32127.1 - 1.7 8.1 12.8 2.9 7.4 10.4 2.2 2 0 0 2 2 2 0 Exonuclease VII, large subunit UPF0242 PF06785.11 KXH32127.1 - 2.1 8.4 19.1 5.2 7.1 0.2 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Uds1 PF15456.6 KXH32128.1 - 6.4e-33 113.7 6.7 2e-32 112.1 6.7 1.9 1 0 0 1 1 1 1 Up-regulated During Septation Stathmin PF00836.19 KXH32128.1 - 0.0057 16.6 0.3 0.03 14.3 0.3 2.3 1 0 0 1 1 1 1 Stathmin family Spc7 PF08317.11 KXH32128.1 - 5 5.9 7.7 0.49 9.2 3.1 1.6 2 0 0 2 2 2 0 Spc7 kinetochore protein TMF_TATA_bd PF12325.8 KXH32128.1 - 5.6 7.2 9.0 1 9.6 2.2 2.8 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding Peptidase_M1 PF01433.20 KXH32129.1 - 2.2e-44 151.7 0.4 3e-44 151.2 0.4 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 KXH32129.1 - 6.4e-38 129.3 0.0 1.7e-37 128.0 0.0 1.8 2 0 0 2 2 2 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 KXH32129.1 - 1.9e-29 103.1 0.0 3.1e-29 102.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain TbpB_B_D PF01298.18 KXH32129.1 - 0.019 15.4 0.1 0.037 14.4 0.1 1.5 1 0 0 1 1 1 0 C-lobe and N-lobe beta barrels of Tf-binding protein B Svf1 PF08622.10 KXH32129.1 - 0.069 13.2 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Svf1-like N-terminal lipocalin domain Peptidase_M61 PF05299.12 KXH32129.1 - 0.51 10.7 2.7 13 6.2 2.7 2.7 1 1 0 1 1 1 0 M61 glycyl aminopeptidase MLVIN_C PF18697.1 KXH32130.1 - 0.13 12.3 0.0 0.38 10.9 0.0 1.8 1 0 0 1 1 1 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain Ank_2 PF12796.7 KXH32131.1 - 9.4e-64 212.0 14.3 5.3e-15 55.8 0.0 6.3 1 1 6 8 8 8 8 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXH32131.1 - 1.8e-31 107.8 9.2 3e-07 30.6 0.1 7.6 3 2 3 7 7 7 7 Ankyrin repeats (many copies) Ank PF00023.30 KXH32131.1 - 1.1e-28 98.4 15.7 0.00017 21.8 0.1 10.1 10 0 0 10 10 10 8 Ankyrin repeat Ank_3 PF13606.6 KXH32131.1 - 6.3e-28 93.7 11.3 0.028 15.0 0.0 12.4 12 1 1 13 13 13 7 Ankyrin repeat Ank_4 PF13637.6 KXH32131.1 - 2.4e-27 94.9 5.5 1.9e-05 25.1 0.0 8.0 3 2 5 8 8 8 7 Ankyrin repeats (many copies) AAA_16 PF13191.6 KXH32131.1 - 1.8e-08 35.0 0.4 7.3e-08 33.0 0.4 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KXH32131.1 - 3.8e-07 30.5 0.5 1.2e-05 25.6 0.1 3.2 3 0 0 3 3 3 1 AAA domain NACHT PF05729.12 KXH32131.1 - 1.2e-06 28.6 0.2 4.4e-06 26.7 0.1 2.1 2 0 0 2 2 2 1 NACHT domain AAA_25 PF13481.6 KXH32131.1 - 2.1e-05 24.2 0.0 6e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KXH32131.1 - 0.0088 16.5 0.0 0.032 14.7 0.0 2.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 KXH32131.1 - 0.011 15.0 0.0 0.02 14.1 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain DUF2075 PF09848.9 KXH32131.1 - 0.041 13.1 0.0 0.075 12.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RuvB_N PF05496.12 KXH32131.1 - 0.05 13.4 0.0 0.18 11.5 0.0 1.9 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain DnaB_C PF03796.15 KXH32131.1 - 0.074 12.4 0.2 0.22 10.8 0.0 1.9 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain ATPase PF06745.13 KXH32131.1 - 0.12 11.7 0.2 0.79 9.0 0.2 2.1 1 1 0 1 1 1 0 KaiC zf-Di19 PF05605.12 KXH32131.1 - 7.1 7.0 7.2 15 6.0 0.1 3.1 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 KXH32131.1 - 9.2 7.4 13.5 39 5.5 0.3 4.1 3 0 0 3 3 3 0 C2H2-type zinc finger DAO PF01266.24 KXH32132.1 - 1.7e-40 139.7 0.5 2e-40 139.4 0.5 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXH32132.1 - 6.9e-09 35.3 0.0 0.00015 21.1 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXH32132.1 - 5.7e-06 26.4 0.1 0.015 15.3 0.1 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KXH32132.1 - 3.5e-05 23.9 0.1 8.9e-05 22.6 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 KXH32132.1 - 0.00083 18.5 0.3 0.0019 17.4 0.1 1.6 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.14 KXH32132.1 - 0.0038 16.0 0.0 0.027 13.2 0.0 1.9 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 KXH32132.1 - 0.0095 16.5 0.0 0.06 13.9 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXH32132.1 - 0.015 14.4 0.0 1.4 7.9 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_3 PF13738.6 KXH32132.1 - 0.025 13.9 0.0 2.7 7.2 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Glu_dehyd_C PF16912.5 KXH32132.1 - 0.028 13.9 0.0 0.37 10.2 0.0 2.2 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus Lycopene_cycl PF05834.12 KXH32132.1 - 0.049 12.7 0.0 0.52 9.3 0.0 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein Thi4 PF01946.17 KXH32132.1 - 0.096 11.9 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 Thi4 family K_oxygenase PF13434.6 KXH32132.1 - 0.24 10.5 0.0 3 6.9 0.0 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) ICL PF00463.21 KXH32133.1 - 2.1e-300 996.7 1.6 2.4e-300 996.5 1.6 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 KXH32133.1 - 8.4e-12 45.0 0.2 2.8e-11 43.3 0.0 1.8 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase Trehalase PF01204.18 KXH32134.1 - 2.4e-196 653.5 0.0 2.9e-196 653.2 0.0 1.1 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.11 KXH32134.1 - 1.1e-16 60.3 0.1 1.9e-16 59.5 0.1 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain GH-E PF14410.6 KXH32134.1 - 0.11 12.9 0.6 0.47 10.9 0.1 2.3 2 0 0 2 2 2 0 HNH/ENDO VII superfamily nuclease with conserved GHE residues NCA2 PF08637.10 KXH32134.1 - 0.2 10.8 0.0 0.51 9.5 0.0 1.6 1 0 0 1 1 1 0 ATP synthase regulation protein NCA2 Hist_deacetyl PF00850.19 KXH32135.1 - 2.1e-51 175.2 0.0 3.3e-51 174.6 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain RTP801_C PF07809.11 KXH32135.1 - 0.00033 20.5 0.0 0.0007 19.5 0.0 1.5 1 0 0 1 1 1 1 RTP801 C-terminal region Adaptin_binding PF10199.9 KXH32135.1 - 0.015 15.9 1.9 0.034 14.8 1.9 1.6 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 Haspin_kinase PF12330.8 KXH32135.1 - 0.4 9.6 1.9 0.68 8.8 1.9 1.3 1 0 0 1 1 1 0 Haspin like kinase domain PHP PF02811.19 KXH32136.1 - 8.3e-11 42.5 0.0 4.6e-10 40.0 0.0 1.9 1 1 0 1 1 1 1 PHP domain Steroid_dh PF02544.16 KXH32137.1 - 4.7e-32 111.0 0.6 6.7e-32 110.5 0.6 1.2 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 KXH32137.1 - 0.00024 20.7 1.1 0.00045 19.8 0.7 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF1295) PEMT PF04191.13 KXH32137.1 - 0.092 13.1 0.2 0.49 10.8 0.1 2.1 2 0 0 2 2 2 0 Phospholipid methyltransferase LSM14 PF12701.7 KXH32139.1 - 4.5e-32 110.0 0.1 6.7e-32 109.4 0.1 1.3 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.10 KXH32139.1 - 1.1e-22 80.8 0.4 2.4e-22 79.8 0.4 1.5 1 0 0 1 1 1 1 FDF domain SM-ATX PF14438.6 KXH32139.1 - 1.5e-07 31.5 0.0 2.6e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Ataxin 2 SM domain Tcf25 PF04910.14 KXH32140.1 - 9.4e-61 205.8 0.2 2.2e-60 204.6 0.0 1.7 2 0 0 2 2 2 1 Transcriptional repressor TCF25 DUF1604 PF07713.13 KXH32141.1 - 1.1e-40 137.3 0.5 5.2e-40 135.1 0.7 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1604) G-patch PF01585.23 KXH32141.1 - 2.8e-06 27.1 2.3 1.2e-05 25.1 1.4 2.4 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 KXH32141.1 - 0.00014 21.9 2.1 0.00018 21.6 0.2 2.2 2 0 0 2 2 2 1 G-patch domain Pkinase PF00069.25 KXH32142.1 - 1.1e-70 238.0 0.0 2.4e-70 236.9 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXH32142.1 - 8.5e-40 136.7 0.1 2.8e-39 135.0 0.1 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 KXH32142.1 - 4.2e-20 71.3 0.3 7.5e-20 70.5 0.3 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 Haspin_kinase PF12330.8 KXH32142.1 - 3.8e-07 29.4 0.0 6.1e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KXH32142.1 - 1.8e-05 24.2 0.2 3.4e-05 23.3 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KXH32142.1 - 5.7e-05 22.6 0.0 0.00013 21.4 0.0 1.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KXH32142.1 - 0.0024 17.8 0.0 0.011 15.6 0.0 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KXH32142.1 - 0.013 15.1 0.0 0.039 13.6 0.0 1.8 1 0 0 1 1 1 0 RIO1 family SDP_N PF12278.8 KXH32142.1 - 0.02 15.0 0.4 0.02 15.0 0.4 5.0 4 1 1 5 5 5 0 Sex determination protein N terminal YrbL-PhoP_reg PF10707.9 KXH32142.1 - 0.08 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL RPAP1_N PF08621.10 KXH32143.1 - 7.4e-20 70.5 6.8 1.1e-19 69.9 6.8 1.3 1 0 0 1 1 1 1 RPAP1-like, N-terminal HUN PF08729.10 KXH32144.1 - 2.3e-07 30.7 0.7 5.6e-07 29.5 0.7 1.6 1 0 0 1 1 1 1 HPC2 and ubinuclein domain FoP_duplication PF13865.6 KXH32144.1 - 5 7.7 18.7 31 5.2 18.7 2.5 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 FYVE_2 PF02318.16 KXH32241.1 - 0.0044 17.2 21.8 0.74 10.0 3.0 3.5 3 0 0 3 3 3 3 FYVE-type zinc finger IBR PF01485.21 KXH32241.1 - 7.1 6.9 37.9 0.69 10.2 5.6 3.7 3 1 0 3 3 3 0 IBR domain, a half RING-finger domain Clr2 PF10383.9 KXH32242.1 - 7.8e-13 49.4 0.2 4.5e-10 40.5 0.0 2.9 2 0 0 2 2 2 1 Transcription-silencing protein Clr2 Clr2_transil PF16761.5 KXH32242.1 - 5.9e-08 33.4 1.2 1.5e-07 32.1 1.2 1.7 1 1 0 1 1 1 1 Transcription-silencing protein, cryptic loci regulator Clr2 Ndc1_Nup PF09531.10 KXH32242.1 - 9.3 4.8 10.9 14 4.2 10.9 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SMC_Nse1 PF07574.13 KXH32247.1 - 1.7e-73 246.7 0.1 2.3e-73 246.2 0.1 1.2 1 0 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.11 KXH32247.1 - 4.2e-15 55.8 12.5 6.8e-15 55.1 12.5 1.3 1 0 0 1 1 1 1 RING-like domain zf-HC5HC2H PF13771.6 KXH32247.1 - 0.07 13.4 4.6 0.17 12.1 4.6 1.7 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-RING_2 PF13639.6 KXH32247.1 - 0.15 12.4 8.8 0.26 11.6 8.8 1.4 1 0 0 1 1 1 0 Ring finger domain Rpr2 PF04032.16 KXH32247.1 - 0.62 10.4 4.3 1.5 9.2 4.3 1.6 1 0 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain C1_2 PF03107.16 KXH32247.1 - 0.85 10.0 6.0 0.42 11.0 1.7 2.2 2 0 0 2 2 2 0 C1 domain zinc-ribbons_6 PF07191.12 KXH32247.1 - 2.3 8.2 8.3 5.8 7.0 1.4 2.3 1 1 0 2 2 2 0 zinc-ribbons PHINT_rpt PF14882.6 KXH32248.1 - 0.14 12.4 1.9 0.39 11.0 1.9 1.8 1 0 0 1 1 1 0 Phage-integrase repeat unit SPRY PF00622.28 KXH32249.1 - 0.02 15.0 0.1 0.22 11.6 0.0 2.6 3 0 0 3 3 3 0 SPRY domain Mito_carr PF00153.27 KXH32250.1 - 4.8e-59 196.3 0.2 4.7e-21 74.5 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein Peptidase_S24 PF00717.23 KXH32250.1 - 0.0012 18.7 0.0 0.0052 16.7 0.0 2.0 1 1 0 1 1 1 1 Peptidase S24-like EIF_2_alpha PF07541.12 KXH32251.1 - 2.6e-37 127.5 0.0 5.3e-37 126.5 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 KXH32251.1 - 4.1e-14 52.7 0.9 8.9e-14 51.6 0.9 1.6 1 0 0 1 1 1 1 S1 RNA binding domain WD40 PF00400.32 KXH32252.1 - 7.1e-11 42.5 0.0 0.058 14.3 0.0 4.5 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXH32252.1 - 0.00028 21.1 0.0 3.1 8.2 0.0 4.1 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Aldo_ket_red PF00248.21 KXH32254.1 - 9.4e-66 222.0 0.0 1.2e-65 221.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family TPR_7 PF13176.6 KXH32255.1 - 0.2 11.8 0.6 7.5 6.8 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat SH3_9 PF14604.6 KXH32256.1 - 0.00013 21.7 0.1 0.00026 20.8 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KXH32256.1 - 0.00014 21.4 0.1 0.00031 20.3 0.1 1.5 1 0 0 1 1 1 1 SH3 domain Gly-zipper_Omp PF13488.6 KXH32256.1 - 0.023 14.7 11.5 0.087 12.8 0.1 2.4 2 0 0 2 2 2 0 Glycine zipper DAP10 PF07213.11 KXH32256.1 - 0.037 14.0 0.3 0.13 12.2 0.3 1.9 1 0 0 1 1 1 0 DAP10 membrane protein Insulin_TMD PF17870.1 KXH32256.1 - 0.23 11.6 0.1 0.46 10.6 0.1 1.5 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment CYYR1 PF10873.8 KXH32256.1 - 4.3 7.8 11.5 0.056 13.9 1.3 2.6 1 1 0 2 2 2 0 Cysteine and tyrosine-rich protein 1 Gly-zipper_YMGG PF13441.6 KXH32256.1 - 9.5 6.1 16.2 0.97 9.2 0.7 2.3 2 0 0 2 2 2 0 YMGG-like Gly-zipper Pkinase PF00069.25 KXH32257.1 - 8.6e-20 71.2 0.0 1.5e-19 70.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain HEAT PF02985.22 KXH32257.1 - 6.3e-11 41.6 7.7 0.062 13.6 0.1 6.7 6 0 0 6 6 6 3 HEAT repeat WD40 PF00400.32 KXH32257.1 - 1.5e-09 38.3 12.8 1.8e-06 28.5 0.2 5.4 5 0 0 5 5 5 2 WD domain, G-beta repeat HEAT_2 PF13646.6 KXH32257.1 - 5.5e-06 26.7 1.1 1.3 9.5 0.1 4.7 2 2 2 4 4 4 3 HEAT repeats LRR_9 PF14580.6 KXH32257.1 - 5.2e-05 22.8 1.9 0.0019 17.8 0.0 3.1 3 0 0 3 3 3 1 Leucine-rich repeat Pkinase_Tyr PF07714.17 KXH32257.1 - 0.00012 21.4 0.0 0.00021 20.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_EZ PF13513.6 KXH32257.1 - 0.0052 17.3 0.5 0.25 11.9 0.2 3.4 2 0 0 2 2 2 1 HEAT-like repeat Kinase-like PF14531.6 KXH32257.1 - 0.032 13.5 0.0 0.059 12.7 0.0 1.4 1 0 0 1 1 1 0 Kinase-like ANAPC4_WD40 PF12894.7 KXH32257.1 - 0.043 14.1 0.0 4.3 7.7 0.0 2.6 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain DUF4349 PF14257.6 KXH32257.1 - 0.055 12.9 1.6 0.094 12.2 1.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) CBFD_NFYB_HMF PF00808.23 KXH32258.1 - 7.2e-12 45.4 0.1 2.1e-11 43.9 0.0 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Pol_alpha_B_N PF08418.10 KXH32258.1 - 0.018 15.0 1.1 0.022 14.7 1.1 1.1 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Voltage_CLC PF00654.20 KXH32259.1 - 4.4e-88 295.9 26.9 4.4e-88 295.9 26.9 1.8 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 KXH32259.1 - 7e-11 42.4 0.1 3.8e-05 24.1 0.0 2.7 2 0 0 2 2 2 2 CBS domain EamA PF00892.20 KXH32260.1 - 0.00011 22.4 13.8 0.00088 19.4 13.8 1.9 1 1 0 1 1 1 1 EamA-like transporter family Trp_oprn_chp PF09534.10 KXH32260.1 - 0.0015 18.3 0.2 0.17 11.6 0.0 2.2 2 0 0 2 2 2 2 Tryptophan-associated transmembrane protein (Trp_oprn_chp) TMEM234 PF10639.9 KXH32260.1 - 0.07 13.2 3.5 0.11 12.5 3.4 1.4 1 1 0 1 1 1 0 Putative transmembrane family 234 TFIIA_gamma_C PF02751.14 KXH32261.1 - 4.4e-24 84.3 0.9 7.2e-24 83.7 0.9 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.16 KXH32261.1 - 2.5e-23 81.8 0.3 3.4e-23 81.4 0.3 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain NOA36 PF06524.12 KXH32261.1 - 0.16 11.3 0.0 0.18 11.1 0.0 1.1 1 0 0 1 1 1 0 NOA36 protein ATP-synt_C PF00137.21 KXH32262.1 - 1.1e-24 86.5 33.8 6.9e-15 55.1 10.7 2.9 3 0 0 3 3 3 2 ATP synthase subunit C MoCF_biosynth PF00994.24 KXH32263.1 - 6.7e-53 178.2 0.8 1.2e-28 99.5 0.0 2.5 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.17 KXH32263.1 - 1.3e-40 138.8 1.9 2.1e-40 138.0 1.9 1.4 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.15 KXH32263.1 - 5.6e-17 61.7 0.0 1.9e-16 60.0 0.0 2.0 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) SelP_N PF04592.14 KXH32263.1 - 0.14 11.6 11.9 0.22 10.9 11.9 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region RNase_P_Rpp14 PF01900.19 KXH32264.1 - 8.5e-39 131.9 0.0 1.1e-38 131.6 0.0 1.1 1 0 0 1 1 1 1 Rpp14/Pop5 family ATP_bind_1 PF03029.17 KXH32265.1 - 3.5e-79 266.0 0.0 5.1e-79 265.5 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein MeaB PF03308.16 KXH32265.1 - 0.0084 15.1 0.0 0.017 14.1 0.0 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_31 PF13614.6 KXH32265.1 - 0.012 15.5 0.0 0.89 9.4 0.0 2.4 1 1 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KXH32265.1 - 0.014 15.1 0.0 0.028 14.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KXH32265.1 - 0.062 13.4 0.0 0.61 10.2 0.0 2.4 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_17 PF13207.6 KXH32265.1 - 0.082 13.3 0.1 0.21 12.0 0.1 1.7 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KXH32265.1 - 0.094 12.0 0.0 0.26 10.6 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin KTI12 PF08433.10 KXH32265.1 - 0.096 12.1 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 GTP_EFTU PF00009.27 KXH32265.1 - 0.12 11.9 0.0 1.2 8.7 0.0 2.3 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_33 PF13671.6 KXH32265.1 - 0.19 11.9 0.6 0.52 10.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KXH32265.1 - 0.26 11.8 1.5 0.38 11.3 0.1 2.1 2 1 0 2 2 2 0 AAA domain cNMP_binding PF00027.29 KXH32266.1 - 2.7e-28 97.9 0.8 1.4e-15 57.1 0.1 5.6 6 0 0 6 6 6 4 Cyclic nucleotide-binding domain Patatin PF01734.22 KXH32266.1 - 8.5e-15 55.5 4.6 2.3e-13 50.8 4.6 2.7 1 1 0 1 1 1 1 Patatin-like phospholipase DUF4834 PF16118.5 KXH32267.1 - 0.16 13.0 0.3 0.16 13.0 0.3 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) Pyridoxal_deC PF00282.19 KXH32269.1 - 3e-109 365.2 0.0 3.5e-109 364.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Glyco_hydro_76 PF03663.14 KXH32271.1 - 7.4e-43 147.5 18.9 8.2e-42 144.0 18.8 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 KXH32271.1 - 4e-07 29.4 1.1 0.02 14.0 0.0 3.2 2 2 1 3 3 3 2 Glycosyl Hydrolase Family 88 C5-epim_C PF06662.13 KXH32271.1 - 0.012 15.1 0.1 0.041 13.4 0.0 1.9 1 1 0 1 1 1 0 D-glucuronyl C5-epimerase C-terminus fn3_3 PF14686.6 KXH32273.1 - 2.6e-27 94.4 1.2 6.8e-27 93.1 1.2 1.8 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II CBM-like PF14683.6 KXH32273.1 - 3.6e-22 79.0 0.0 6.4e-22 78.2 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain III Nudix_N PF12535.8 KXH32273.1 - 0.082 12.5 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Hydrolase of X-linked nucleoside diphosphate N terminal DUF2220 PF09983.9 KXH32273.1 - 0.14 11.5 0.0 0.38 10.1 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria C-term(DUF2220) Utp21 PF04192.12 KXH32274.1 - 2.1e-82 276.1 0.0 3.2e-82 275.5 0.0 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.32 KXH32274.1 - 2.8e-16 59.6 21.4 3.4e-06 27.7 0.6 9.1 9 0 0 9 9 9 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXH32274.1 - 2.1e-13 50.4 0.0 0.0011 19.2 0.0 6.3 2 2 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KXH32274.1 - 2.4e-05 23.2 1.0 0.85 8.2 0.0 3.7 2 1 0 3 3 3 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 KXH32274.1 - 0.00022 19.9 0.0 0.00038 19.1 0.0 1.3 1 0 0 1 1 1 1 Cytochrome D1 heme domain PALB2_WD40 PF16756.5 KXH32274.1 - 0.008 15.1 0.0 0.6 9.0 0.0 2.8 3 0 0 3 3 3 1 Partner and localizer of BRCA2 WD40 domain Nucleoporin_N PF08801.11 KXH32274.1 - 0.058 12.1 0.0 3 6.5 0.0 2.3 1 1 1 2 2 2 0 Nup133 N terminal like His_Phos_2 PF00328.22 KXH32275.1 - 2.2e-112 376.2 0.2 9e-111 370.9 0.2 2.2 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 KXH32275.1 - 2.6e-36 123.6 0.1 5e-36 122.7 0.1 1.4 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 KXH32275.1 - 9e-06 25.4 0.0 1.6e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 RimK-like ATP-grasp domain MOSC PF03473.17 KXH32276.1 - 7.2e-24 84.3 0.0 1e-23 83.8 0.0 1.2 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 KXH32276.1 - 6.5e-10 38.9 0.0 1.4e-09 37.9 0.0 1.7 1 1 0 1 1 1 1 MOSC N-terminal beta barrel domain NAD_binding_10 PF13460.6 KXH32277.1 - 4.1e-16 59.4 0.0 8.7e-16 58.3 0.0 1.6 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KXH32277.1 - 2.2e-12 47.1 0.1 3.4e-12 46.4 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family Shikimate_DH PF01488.20 KXH32277.1 - 0.00023 21.2 0.0 0.00039 20.5 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_2 PF03446.15 KXH32277.1 - 0.00032 20.9 0.0 0.00059 20.0 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 KXH32277.1 - 0.001 19.0 0.1 0.0017 18.3 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 KXH32277.1 - 0.035 14.3 0.0 0.071 13.4 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 KXH32277.1 - 0.061 12.8 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family LytR_C PF13399.6 KXH32277.1 - 0.065 14.2 0.5 0.36 11.8 0.0 2.2 2 0 0 2 2 2 0 LytR cell envelope-related transcriptional attenuator NAD_Gly3P_dh_N PF01210.23 KXH32277.1 - 0.12 12.3 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Zn_clus PF00172.18 KXH32278.1 - 1.1e-09 38.3 9.9 1.1e-09 38.3 9.9 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXH32278.1 - 3.1e-08 33.0 0.1 4.6e-08 32.4 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain HrpB1_HrpK PF09613.10 KXH32278.1 - 0.13 11.9 0.5 1.4 8.6 0.1 2.6 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) PLA2_B PF01735.18 KXH32279.1 - 7.5e-84 281.9 5.3 2.4e-83 280.2 5.3 1.7 1 1 0 1 1 1 1 Lysophospholipase catalytic domain Pkinase PF00069.25 KXH32392.1 - 2.2e-59 201.0 0.0 2.7e-59 200.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXH32392.1 - 4.8e-32 111.2 0.0 6.3e-32 110.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXH32392.1 - 0.0011 18.4 0.0 0.0019 17.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KXH32392.1 - 0.0031 16.9 0.0 0.0054 16.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KXH32392.1 - 0.019 13.8 0.0 0.028 13.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 KXH32392.1 - 0.048 13.6 0.2 0.048 13.6 0.2 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family zf-RING_2 PF13639.6 KXH32394.1 - 1.2e-10 41.5 4.9 1.9e-10 40.9 4.9 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KXH32394.1 - 3.6e-07 30.4 5.5 2.2e-06 27.9 5.5 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KXH32394.1 - 9e-07 28.9 0.9 1.5e-06 28.2 0.9 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 KXH32394.1 - 4.5e-05 23.4 2.6 4.8e-05 23.3 1.3 1.7 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KXH32394.1 - 4.6e-05 23.2 6.0 0.00017 21.4 6.1 1.9 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KXH32394.1 - 0.00014 21.6 2.8 0.0003 20.6 2.7 1.6 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXH32394.1 - 0.0011 18.7 3.2 0.0018 18.1 3.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KXH32394.1 - 0.0017 18.1 4.7 0.2 11.5 1.5 2.3 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 FANCL_C PF11793.8 KXH32394.1 - 0.006 16.7 2.6 0.26 11.5 2.8 2.5 2 1 0 2 2 1 1 FANCL C-terminal domain zf-RING_4 PF14570.6 KXH32394.1 - 0.0081 15.9 3.6 0.02 14.6 3.6 1.7 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.5 KXH32394.1 - 0.0083 15.8 1.4 0.018 14.7 1.4 1.6 1 0 0 1 1 1 1 RING-like zinc finger Rad50_zn_hook PF04423.14 KXH32394.1 - 0.011 15.5 3.6 0.82 9.6 0.3 2.5 2 0 0 2 2 2 0 Rad50 zinc hook motif UBZ_FAAP20 PF15750.5 KXH32394.1 - 0.026 14.5 4.8 1.7 8.6 0.2 3.2 3 0 0 3 3 3 0 Ubiquitin-binding zinc-finger Prok-RING_1 PF14446.6 KXH32394.1 - 0.063 13.2 4.9 3.4 7.7 0.6 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-Di19 PF05605.12 KXH32394.1 - 0.065 13.5 2.3 6.3 7.2 0.3 2.5 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-RING_5 PF14634.6 KXH32394.1 - 0.065 13.2 1.5 0.14 12.2 1.6 1.5 1 1 0 1 1 1 0 zinc-RING finger domain DUF1796 PF08795.10 KXH32394.1 - 0.078 12.9 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Putative papain-like cysteine peptidase (DUF1796) Zn-C2H2_12 PF18112.1 KXH32394.1 - 0.3 11.6 3.4 5.3 7.6 0.1 2.5 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain Tmpp129 PF10272.9 KXH32394.1 - 0.32 10.3 1.8 0.41 9.9 0.4 1.7 2 0 0 2 2 2 0 Putative transmembrane protein precursor zf-UDP PF14569.6 KXH32394.1 - 0.55 10.4 4.8 2.8 8.1 4.8 2.0 1 1 0 1 1 1 0 Zinc-binding RING-finger Pheromone PF08015.11 KXH32394.1 - 1.9 9.6 11.9 2.6 9.2 3.8 2.4 2 0 0 2 2 2 0 Fungal mating-type pheromone zf-C3HC4_5 PF17121.5 KXH32394.1 - 2.7 8.0 5.3 16 5.5 5.4 2.2 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Cation_efflux PF01545.21 KXH32407.1 - 4.2e-48 163.7 0.1 6.4e-48 163.1 0.1 1.3 1 0 0 1 1 1 1 Cation efflux family Transport_MerF PF11431.8 KXH32407.1 - 0.31 11.0 2.9 12 5.8 0.4 3.0 2 0 0 2 2 2 0 Membrane transport protein MerF CrgA PF06781.12 KXH32407.1 - 0.48 10.5 1.6 5.2 7.2 0.0 2.7 2 1 1 3 3 3 0 Cell division protein CrgA IML1 PF12257.8 KXH32408.1 - 2.1e-120 401.2 0.0 2.9e-120 400.7 0.0 1.2 1 0 0 1 1 1 1 Vacuolar membrane-associated protein Iml1 DEP PF00610.21 KXH32408.1 - 6.3e-26 90.2 0.2 1.3e-25 89.2 0.2 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Na_Ca_ex PF01699.24 KXH32409.1 - 9.3e-44 149.0 35.0 1.2e-23 83.7 13.9 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Glyco_hyd_65N_2 PF14498.6 KXH32410.1 - 8.3e-48 163.3 0.1 1.2e-47 162.7 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain FAD_binding_4 PF01565.23 KXH32411.1 - 5.8e-33 113.6 5.9 1.4e-32 112.3 5.9 1.6 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 KXH32411.1 - 1.7e-07 31.2 0.1 3.4e-07 30.3 0.1 1.4 1 0 0 1 1 1 1 Berberine and berberine like CVNH PF08881.10 KXH32412.1 - 1.4e-05 25.7 0.1 1.9e-05 25.3 0.1 1.3 1 0 0 1 1 1 1 CVNH domain Acyltransferase PF01553.21 KXH32417.1 - 9.9e-22 77.0 0.0 1.5e-21 76.4 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 KXH32417.1 - 1.1e-12 47.9 0.1 2e-12 47.0 0.1 1.4 1 0 0 1 1 1 1 Acyltransferase C-terminus ADH_zinc_N PF00107.26 KXH32418.1 - 1.1e-08 35.1 0.2 2.2e-08 34.1 0.2 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXH32418.1 - 4.1e-08 33.1 0.1 9.7e-08 31.9 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXH32419.1 - 9.7e-13 48.2 0.0 2.1e-12 47.2 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXH32419.1 - 1.3e-08 34.7 0.0 2.9e-08 33.6 0.0 1.6 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KXH32419.1 - 9.7e-08 33.1 0.0 1.8e-07 32.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase p450 PF00067.22 KXH32420.1 - 1.6e-56 192.0 0.0 2.1e-56 191.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 EphA2_TM PF14575.6 KXH32421.1 - 0.13 13.1 0.1 0.19 12.6 0.1 1.4 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 KXH32421.1 - 0.18 11.7 0.0 0.47 10.3 0.0 1.7 2 0 0 2 2 2 0 TMEM154 protein family BNR_4 PF15892.5 KXH32422.1 - 8.2e-67 225.4 0.6 1.1e-66 225.0 0.6 1.1 1 0 0 1 1 1 1 BNR repeat-containing family member DUF5124 PF17160.4 KXH32422.1 - 0.011 16.4 0.1 0.022 15.5 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5124) Sugar_tr PF00083.24 KXH32423.1 - 8.1e-77 259.0 21.3 9.3e-77 258.8 21.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH32423.1 - 1.2e-25 90.2 28.1 1.2e-25 90.2 28.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Git3 PF11710.8 KXH32424.1 - 9e-10 38.7 1.4 2.1e-09 37.5 1.4 1.6 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 GPR_Gpa2_C PF11970.8 KXH32424.1 - 0.00031 20.7 0.1 0.00078 19.5 0.1 1.6 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term 7tm_1 PF00001.21 KXH32424.1 - 0.0063 15.9 0.3 0.012 15.0 0.3 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Abhydrolase_4 PF08386.10 KXH32425.1 - 1.9e-17 63.3 0.0 3.9e-17 62.3 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.20 KXH32425.1 - 9.1e-16 58.3 0.1 3.4e-06 26.9 0.0 3.1 3 0 0 3 3 3 3 alpha/beta hydrolase fold HET PF06985.11 KXH32427.1 - 4.3e-34 118.0 0.2 7.7e-34 117.1 0.2 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF815 PF05673.13 KXH32427.1 - 0.18 10.9 0.0 0.33 10.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) TPR_12 PF13424.6 KXH32429.1 - 1.2e-29 102.4 14.9 2.5e-10 40.5 0.8 5.6 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_10 PF13374.6 KXH32429.1 - 4.4e-28 96.3 13.8 2.1e-06 27.4 0.3 6.8 6 0 0 6 6 6 6 Tetratricopeptide repeat SesA PF17107.5 KXH32429.1 - 1.7e-14 54.1 0.0 6.8e-14 52.1 0.0 2.1 2 0 0 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases NB-ARC PF00931.22 KXH32429.1 - 1.6e-10 40.7 0.0 4.8e-06 25.9 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain TPR_MalT PF17874.1 KXH32429.1 - 4.3e-08 32.9 6.8 1.5e-05 24.6 1.2 2.5 1 1 1 2 2 2 2 MalT-like TPR region TPR_2 PF07719.17 KXH32429.1 - 0.00029 20.7 10.3 2.2 8.6 0.2 6.5 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_4 PF07721.14 KXH32429.1 - 0.0021 18.5 21.6 4 8.3 4.0 6.8 7 0 0 7 7 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 KXH32429.1 - 0.0049 16.5 2.0 0.18 11.5 0.1 3.6 4 0 0 4 4 4 1 TPR repeat TPR_8 PF13181.6 KXH32429.1 - 0.0074 16.4 0.5 65 4.1 0.1 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 KXH32429.1 - 0.0085 15.9 2.6 4.4 7.3 0.1 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 KXH32429.1 - 0.029 14.9 18.6 0.05 14.1 0.3 4.5 5 1 1 6 6 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 KXH32429.1 - 0.11 12.6 11.9 2.8 8.2 0.1 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 KXH32429.1 - 0.18 12.5 9.9 6.3 7.7 0.0 5.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 KXH32429.1 - 0.32 11.9 22.5 0.65 11.0 1.7 7.1 6 1 1 7 7 6 0 Tetratricopeptide repeat TPR_16 PF13432.6 KXH32429.1 - 0.89 10.3 21.5 1.7 9.3 1.9 6.4 5 2 1 6 6 5 0 Tetratricopeptide repeat Amino_oxidase PF01593.24 KXH32430.1 - 1.2e-45 156.6 0.3 6.1e-45 154.3 0.3 2.1 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KXH32430.1 - 2.5e-14 53.2 0.1 5.4e-14 52.2 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXH32430.1 - 2.2e-07 30.4 0.2 4.7e-05 22.8 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXH32430.1 - 5.6e-05 22.4 0.1 8.1e-05 21.9 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 KXH32430.1 - 7.8e-05 23.2 1.5 0.00042 20.8 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXH32430.1 - 0.00016 20.5 1.0 0.0015 17.3 0.4 2.0 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.24 KXH32430.1 - 0.00027 20.7 1.4 0.00073 19.2 1.4 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 KXH32430.1 - 0.0036 16.6 0.0 0.0066 15.8 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 KXH32430.1 - 0.0044 16.3 0.7 0.0072 15.6 0.7 1.3 1 0 0 1 1 1 1 FAD binding domain 3HCDH_N PF02737.18 KXH32430.1 - 0.017 15.0 0.2 0.055 13.3 0.2 1.9 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.17 KXH32430.1 - 0.038 13.2 1.6 0.078 12.2 0.1 2.0 2 0 0 2 2 2 0 Thi4 family NAD_binding_7 PF13241.6 KXH32430.1 - 0.046 14.2 0.0 0.13 12.8 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding NAD_binding_9 PF13454.6 KXH32430.1 - 0.054 13.5 4.2 2.1 8.3 0.4 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_oxidored PF12831.7 KXH32430.1 - 0.12 11.7 1.0 0.2 11.0 0.5 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KXH32430.1 - 0.46 9.5 1.3 1.7 7.6 0.8 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein GIDA PF01134.22 KXH32430.1 - 1.1 8.3 3.8 0.48 9.5 0.7 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 KXH32430.1 - 1.3 8.2 3.4 2 7.6 0.3 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KXH32431.1 - 7.9e-54 183.0 0.0 1.1e-52 179.2 0.0 2.3 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KXH32431.1 - 4.9e-18 65.4 0.0 6.8e-12 45.3 0.0 3.1 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXH32431.1 - 2.2e-14 53.4 0.0 2.5e-09 36.8 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXH32431.1 - 3.2e-06 26.5 0.0 4.9e-05 22.6 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KXH32431.1 - 4.2e-06 26.8 0.1 2.1 8.3 0.0 3.5 3 0 0 3 3 3 3 FAD-NAD(P)-binding NAD_binding_2 PF03446.15 KXH32431.1 - 0.0016 18.7 0.1 0.06 13.5 0.0 2.6 3 0 0 3 3 3 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_8 PF13450.6 KXH32431.1 - 0.0022 18.2 0.0 0.0089 16.2 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KXH32431.1 - 0.0026 18.3 0.8 1.8 9.2 0.0 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase IlvN PF07991.12 KXH32431.1 - 0.0026 17.3 0.0 0.35 10.4 0.0 2.3 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain 2-Hacid_dh_C PF02826.19 KXH32431.1 - 0.0053 16.1 0.0 0.6 9.4 0.0 2.4 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KXH32431.1 - 0.013 15.6 0.0 1 9.4 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DAO PF01266.24 KXH32431.1 - 0.018 14.7 0.3 4.5 6.8 0.0 3.3 3 1 0 4 4 4 0 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.14 KXH32431.1 - 0.037 13.6 0.2 0.22 11.1 0.0 2.0 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ThiF PF00899.21 KXH32431.1 - 0.078 12.3 0.1 2.5 7.4 0.0 2.4 2 0 0 2 2 2 0 ThiF family NAD_binding_7 PF13241.6 KXH32431.1 - 0.099 13.1 0.1 3.7 8.0 0.0 2.4 2 1 0 2 2 2 0 Putative NAD(P)-binding TrkA_N PF02254.18 KXH32431.1 - 0.16 12.3 0.2 4 7.7 0.0 2.8 4 0 0 4 4 3 0 TrkA-N domain Tannase PF07519.11 KXH32432.1 - 2.4e-88 297.1 0.1 3e-88 296.8 0.1 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_S9 PF00326.21 KXH32432.1 - 0.024 14.1 0.1 1 8.8 0.1 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family GFO_IDH_MocA PF01408.22 KXH32435.1 - 1.7e-24 87.0 0.0 2.5e-24 86.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KXH32435.1 - 5.8e-15 55.3 0.0 9.7e-15 54.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain DUF4734 PF15881.5 KXH32435.1 - 0.015 15.4 0.0 0.041 14.1 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4734) NAD_binding_3 PF03447.16 KXH32435.1 - 0.042 14.5 0.0 0.074 13.7 0.0 1.3 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain 7tm_7 PF08395.12 KXH32437.1 - 0.66 9.1 2.9 1.4 8.0 0.4 2.0 1 1 0 2 2 2 0 7tm Chemosensory receptor MARVEL PF01284.23 KXH32438.1 - 0.023 14.7 1.9 7 6.7 1.3 2.2 2 0 0 2 2 2 0 Membrane-associating domain ABC_tran PF00005.27 KXH32439.1 - 6.2e-48 162.8 0.0 2.8e-23 82.9 0.0 2.9 3 0 0 3 3 2 2 ABC transporter ABC_tran_Xtn PF12848.7 KXH32439.1 - 1.2e-19 70.1 0.8 1.2e-19 70.1 0.8 2.6 3 0 0 3 3 1 1 ABC transporter AAA_21 PF13304.6 KXH32439.1 - 4.3e-19 69.5 0.9 0.00011 22.1 0.0 4.2 3 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KXH32439.1 - 2.7e-12 46.6 0.6 0.00013 21.4 0.1 4.9 4 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KXH32439.1 - 3.9e-09 36.1 0.0 0.003 17.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 KXH32439.1 - 6.1e-08 33.4 6.1 0.0095 16.5 0.0 3.7 4 0 0 4 4 3 2 AAA domain RsgA_GTPase PF03193.16 KXH32439.1 - 1.6e-06 28.1 0.0 0.0049 16.8 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KXH32439.1 - 3.1e-06 27.2 0.0 0.016 15.3 0.0 3.2 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_16 PF13191.6 KXH32439.1 - 4.2e-06 27.2 0.0 0.018 15.4 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_15 PF13175.6 KXH32439.1 - 8.6e-06 25.7 3.1 0.045 13.5 0.0 3.2 4 1 0 4 4 3 2 AAA ATPase domain AAA_22 PF13401.6 KXH32439.1 - 9.1e-06 26.0 0.1 0.054 13.8 0.1 2.6 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 KXH32439.1 - 2.3e-05 24.7 0.0 0.014 15.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KXH32439.1 - 4.2e-05 24.0 0.0 0.4 11.1 0.0 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KXH32439.1 - 5.1e-05 23.8 0.0 0.27 11.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 KXH32439.1 - 9.8e-05 22.4 0.2 0.47 10.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) NACHT PF05729.12 KXH32439.1 - 0.0001 22.3 0.1 0.2 11.6 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_27 PF13514.6 KXH32439.1 - 0.00028 20.5 0.0 0.066 12.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KXH32439.1 - 0.00035 20.8 0.0 0.49 10.6 0.1 2.8 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KXH32439.1 - 0.00039 20.8 0.0 1.6 9.2 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA_14 PF13173.6 KXH32439.1 - 0.0011 19.0 0.0 1.9 8.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain Roc PF08477.13 KXH32439.1 - 0.0012 19.0 0.0 2.1 8.6 0.1 3.0 2 1 1 3 3 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 KXH32439.1 - 0.0024 17.6 1.7 1.9 8.2 0.0 3.6 4 0 0 4 4 4 1 AAA domain AAA_25 PF13481.6 KXH32439.1 - 0.0039 16.8 0.0 0.68 9.5 0.0 2.9 3 0 0 3 3 3 1 AAA domain NB-ARC PF00931.22 KXH32439.1 - 0.0042 16.3 0.0 6.5 5.8 0.0 3.1 3 0 0 3 3 3 0 NB-ARC domain AAA_17 PF13207.6 KXH32439.1 - 0.0085 16.5 0.2 4.2 7.8 0.0 3.2 3 0 0 3 3 3 1 AAA domain Dynamin_N PF00350.23 KXH32439.1 - 0.0087 16.1 1.2 8.2 6.5 0.0 3.5 4 1 0 5 5 4 0 Dynamin family DUF2813 PF11398.8 KXH32439.1 - 0.011 15.0 0.0 2.6 7.2 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2813) AAA_7 PF12775.7 KXH32439.1 - 0.02 14.4 0.0 1.9 8.0 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_30 PF13604.6 KXH32439.1 - 0.022 14.5 0.2 2.8 7.6 0.1 2.9 2 1 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 KXH32439.1 - 0.04 13.8 0.0 4.9 7.0 0.0 2.6 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea MCM PF00493.23 KXH32439.1 - 0.048 12.8 0.0 7 5.7 0.0 2.4 2 0 0 2 2 2 0 MCM P-loop domain NTPase_1 PF03266.15 KXH32439.1 - 0.059 13.3 0.3 4.4 7.2 0.2 2.6 2 0 0 2 2 2 0 NTPase DAP3 PF10236.9 KXH32439.1 - 0.072 12.3 0.1 5.9 6.0 0.0 2.6 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 DUF815 PF05673.13 KXH32439.1 - 0.076 12.2 0.1 3.6 6.7 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Ras PF00071.22 KXH32439.1 - 0.11 12.1 0.0 12 5.5 0.0 2.6 2 0 0 2 2 2 0 Ras family TsaE PF02367.17 KXH32439.1 - 0.11 12.5 0.3 25 4.9 0.0 3.1 2 1 1 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE FeoB_N PF02421.18 KXH32439.1 - 0.12 11.9 0.0 12 5.4 0.0 2.8 2 0 0 2 2 2 0 Ferrous iron transport protein B Rad17 PF03215.15 KXH32439.1 - 0.13 12.1 0.0 23 4.8 0.0 2.5 2 0 0 2 2 2 0 Rad17 P-loop domain DUF3584 PF12128.8 KXH32439.1 - 0.14 9.6 0.6 0.42 8.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) DUF87 PF01935.17 KXH32439.1 - 0.15 12.2 0.6 29 4.7 0.0 2.9 3 0 0 3 3 2 0 Helicase HerA, central domain Adeno_IVa2 PF02456.15 KXH32439.1 - 0.19 10.5 0.1 8.4 5.1 0.0 2.3 2 0 0 2 2 2 0 Adenovirus IVa2 protein SNF2_N PF00176.23 KXH32440.1 - 1.2e-65 221.5 0.8 1.2e-65 221.5 0.8 1.9 2 0 0 2 2 2 1 SNF2 family N-terminal domain DBINO PF13892.6 KXH32440.1 - 4.5e-48 163.0 19.7 4.5e-48 163.0 19.7 7.0 8 0 0 8 8 8 1 DNA-binding domain Helicase_C PF00271.31 KXH32440.1 - 8.3e-20 71.2 0.0 1.8e-19 70.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXH32440.1 - 5.6e-08 33.0 0.0 5.6e-08 33.0 0.0 2.7 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 KXH32440.1 - 0.024 13.8 0.0 0.024 13.8 0.0 4.1 4 0 0 4 4 4 0 Class II histone deacetylase complex subunits 2 and 3 Fe_hyd_lg_C PF02906.14 KXH32440.1 - 0.59 9.7 5.8 0.45 10.1 2.1 2.3 2 0 0 2 2 2 0 Iron only hydrogenase large subunit, C-terminal domain EAV_GS PF01309.18 KXH32441.1 - 1.3 8.6 9.0 0.15 11.7 3.4 2.0 1 1 1 2 2 2 0 Equine arteritis virus small envelope glycoprotein DUF716 PF04819.12 KXH32441.1 - 2.7 7.6 9.5 1.7 8.2 0.7 3.0 2 1 1 3 3 3 0 Family of unknown function (DUF716) Glyco_hydro_28 PF00295.17 KXH32442.1 - 2e-111 372.2 22.9 2.3e-111 372.0 22.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 DUF4957 PF16318.5 KXH32442.1 - 0.053 13.5 5.7 1.7 8.5 5.7 2.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4957) adh_short PF00106.25 KXH32443.1 - 9.4e-25 87.2 0.0 5.8e-20 71.6 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXH32443.1 - 1.2e-11 44.6 0.0 1.3e-09 38.0 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH32443.1 - 1.2e-10 41.6 0.0 1.8e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXH32443.1 - 0.00023 20.7 0.0 0.00037 20.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KXH32443.1 - 0.0092 15.1 0.0 0.014 14.6 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Amidohydro_2 PF04909.14 KXH32443.1 - 0.021 14.6 0.0 0.59 9.9 0.0 2.5 3 0 0 3 3 3 0 Amidohydrolase Glyco_tran_WecB PF03808.13 KXH32443.1 - 0.037 14.0 0.0 6.7 6.6 0.0 2.4 2 1 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family Sacchrp_dh_NADP PF03435.18 KXH32443.1 - 0.039 14.2 0.0 0.13 12.6 0.0 1.8 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 KXH32443.1 - 0.069 13.2 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NUMOD1 PF07453.13 KXH32443.1 - 0.22 11.8 0.5 0.51 10.7 0.1 1.8 2 0 0 2 2 2 0 NUMOD1 domain Glyco_hydro_43 PF04616.14 KXH32444.1 - 7.9e-67 225.6 0.1 9.2e-67 225.4 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Acetyltransf_3 PF13302.7 KXH32445.1 - 4.5e-12 46.8 0.0 6.7e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KXH32445.1 - 0.091 12.9 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain B3 PF02362.21 KXH32448.1 - 0.089 12.7 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 B3 DNA binding domain Glyco_hydro_20 PF00728.22 KXH32449.1 - 2e-28 99.8 0.0 6.6e-28 98.1 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glyco_hydro_20b PF02838.15 KXH32449.1 - 1.9e-07 31.9 0.0 6.7e-07 30.1 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 20, domain 2 DUF3841 PF12952.7 KXH32449.1 - 0.21 11.4 0.1 0.34 10.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3841) HATPase_c PF02518.26 KXH32451.1 - 4.9e-22 78.5 0.2 9.7e-22 77.6 0.2 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KXH32451.1 - 2.6e-18 66.2 0.0 5.6e-18 65.1 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 KXH32451.1 - 4.8e-10 39.3 0.2 3.1e-09 36.8 0.2 2.3 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain AA_permease_2 PF13520.6 KXH32452.1 - 3.1e-62 210.8 55.4 4e-62 210.4 55.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXH32452.1 - 2.1e-26 92.6 51.3 2.8e-26 92.1 51.3 1.0 1 0 0 1 1 1 1 Amino acid permease NUDIX PF00293.28 KXH32453.1 - 5.5e-15 55.6 0.0 7.6e-15 55.1 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain F-box-like PF12937.7 KXH32454.1 - 9.6e-06 25.4 0.7 0.027 14.3 0.4 2.9 2 0 0 2 2 2 2 F-box-like F-box PF00646.33 KXH32454.1 - 0.0012 18.6 4.2 0.35 10.8 0.2 3.3 3 0 0 3 3 3 2 F-box domain F-box-like_2 PF13013.6 KXH32454.1 - 0.0043 17.0 0.2 0.43 10.6 0.0 2.7 2 0 0 2 2 2 1 F-box-like domain SAB PF04382.13 KXH32454.1 - 0.065 13.3 0.0 0.53 10.4 0.0 2.4 2 0 0 2 2 2 0 SAB domain LRR_4 PF12799.7 KXH32454.1 - 0.23 11.9 4.2 13 6.3 0.1 3.9 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) BUD22 PF09073.10 KXH32454.1 - 3.6 6.8 8.1 6.7 5.9 8.1 1.4 1 0 0 1 1 1 0 BUD22 ECSIT_C PF14784.6 KXH32455.1 - 0.0066 16.8 0.0 0.014 15.7 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of the ECSIT protein Glyco_hydro_26 PF02156.15 KXH32456.1 - 7.1e-89 298.3 7.7 9e-89 298.0 7.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 26 CBM_35 PF16990.5 KXH32456.1 - 2.8e-29 101.8 2.4 5.4e-29 100.9 2.4 1.5 1 0 0 1 1 1 1 Carbohydrate binding module (family 35) p450 PF00067.22 KXH32457.1 - 1e-11 44.2 0.1 1.5e-05 24.0 0.2 2.3 2 0 0 2 2 2 2 Cytochrome P450 Glyco_hydro_6 PF01341.17 KXH32458.1 - 4.5e-87 292.6 0.1 6.4e-87 292.1 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 Fimbrial_K88 PF02432.15 KXH32458.1 - 0.06 13.3 0.2 0.11 12.4 0.2 1.4 1 0 0 1 1 1 0 Fimbrial, major and minor subunit p450 PF00067.22 KXH32459.1 - 1.4e-26 93.3 0.2 1.7e-26 93.0 0.2 1.2 1 0 0 1 1 1 1 Cytochrome P450 DUF3025 PF11227.8 KXH32460.1 - 0.17 11.7 0.0 0.22 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3025) MF_alpha_N PF05436.11 KXH32462.1 - 0.099 12.6 0.1 0.13 12.2 0.1 1.2 1 0 0 1 1 1 0 Mating factor alpha precursor N-terminus Fer4_6 PF12837.7 KXH32462.1 - 9.8 6.4 12.7 3.3 8.0 6.2 2.6 2 1 0 2 2 2 0 4Fe-4S binding domain FAD_binding_3 PF01494.19 KXH32467.1 - 9.3e-88 294.8 0.0 1.3e-87 294.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 KXH32467.1 - 3.5e-57 193.1 0.0 5.9e-57 192.3 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain FAD_binding_2 PF00890.24 KXH32467.1 - 3.4e-05 23.1 0.3 6.1e-05 22.3 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KXH32467.1 - 5.7e-05 22.0 0.2 8.7e-05 21.4 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.14 KXH32467.1 - 0.0012 18.2 0.3 0.0025 17.1 0.3 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXH32467.1 - 0.004 16.4 0.1 0.0062 15.8 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXH32467.1 - 0.0058 15.9 0.0 0.031 13.5 0.0 2.0 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 KXH32467.1 - 0.011 16.0 0.1 0.046 14.0 0.1 2.1 2 0 0 2 2 1 0 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 KXH32467.1 - 0.017 14.2 0.4 0.027 13.6 0.4 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 KXH32467.1 - 0.018 14.4 0.0 0.029 13.7 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 KXH32467.1 - 0.024 14.0 0.2 0.039 13.3 0.2 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KXH32467.1 - 0.037 13.1 0.1 0.073 12.1 0.1 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein Trp_halogenase PF04820.14 KXH32467.1 - 0.11 11.3 0.0 0.22 10.3 0.0 1.5 1 0 0 1 1 1 0 Tryptophan halogenase OTT_1508_deam PF14441.6 KXH32469.1 - 8.8e-21 73.7 0.5 1.6e-20 72.9 0.5 1.4 1 0 0 1 1 1 1 OTT_1508-like deaminase Cupin_2 PF07883.11 KXH32471.1 - 9.4e-13 47.7 0.2 1.9e-09 37.1 0.1 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 KXH32471.1 - 0.00029 20.4 0.1 0.055 13.2 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF861) Ppnp PF06865.11 KXH32471.1 - 0.0069 16.8 0.0 0.041 14.3 0.0 2.2 2 0 0 2 2 2 1 Pyrimidine/purine nucleoside phosphorylase AraC_binding PF02311.19 KXH32471.1 - 0.0072 16.2 0.0 0.073 13.0 0.0 2.2 2 0 0 2 2 2 1 AraC-like ligand binding domain Cupin_4 PF08007.12 KXH32471.1 - 0.087 12.3 0.3 0.26 10.7 0.0 1.8 2 0 0 2 2 2 0 Cupin superfamily protein Abhydrolase_3 PF07859.13 KXH32472.1 - 7.1e-15 55.4 0.0 4.9e-09 36.3 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KXH32472.1 - 9.5e-12 44.8 0.1 5.2e-08 32.6 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family COesterase PF00135.28 KXH32472.1 - 3.3e-07 29.6 0.0 5.4e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Peptidase_S15 PF02129.18 KXH32472.1 - 4e-05 23.4 0.0 0.00022 20.9 0.0 2.1 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_2 PF02230.16 KXH32472.1 - 8.4e-05 22.5 0.0 0.055 13.3 0.0 2.3 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase DLH PF01738.18 KXH32472.1 - 0.00019 21.0 0.0 0.00089 18.9 0.0 2.0 3 0 0 3 3 3 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 KXH32472.1 - 0.0016 18.1 0.4 0.76 9.4 0.0 2.8 1 1 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXH32472.1 - 0.005 16.1 0.0 0.16 11.2 0.0 2.6 3 0 0 3 3 3 1 Serine aminopeptidase, S33 LIP PF03583.14 KXH32472.1 - 0.081 12.2 0.3 0.57 9.4 0.0 2.2 3 0 0 3 3 3 0 Secretory lipase FSH1 PF03959.13 KXH32472.1 - 0.091 12.4 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase (FSH1) AXE1 PF05448.12 KXH32472.1 - 0.098 11.3 0.0 0.64 8.6 0.0 1.9 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Sugar_tr PF00083.24 KXH32473.1 - 2.3e-64 217.9 27.8 2.6e-64 217.7 27.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH32473.1 - 1.3e-19 70.4 33.3 1.3e-19 70.4 33.3 2.6 1 1 2 3 3 3 2 Major Facilitator Superfamily MFS_2 PF13347.6 KXH32473.1 - 0.0089 14.6 33.3 0.0062 15.1 10.6 3.1 2 2 1 3 3 3 2 MFS/sugar transport protein DUF2678 PF10856.8 KXH32473.1 - 1.1 9.2 5.3 2.4 8.1 0.3 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF2678) Glyco_hydro_3_C PF01915.22 KXH32474.1 - 7e-56 189.4 0.0 1.5e-55 188.4 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 KXH32474.1 - 7.3e-22 77.3 0.9 1.8e-21 76.0 0.9 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain Glyco_hydro_3 PF00933.21 KXH32474.1 - 8e-15 55.0 0.0 2.1e-14 53.6 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain PA14 PF07691.12 KXH32474.1 - 2e-06 27.7 0.0 3.9e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 PA14 domain GLEYA PF10528.9 KXH32474.1 - 0.0093 16.4 0.0 0.026 14.9 0.0 1.7 1 0 0 1 1 1 1 GLEYA domain WYL_2 PF10902.8 KXH32474.1 - 0.046 14.1 0.3 16 6.0 0.0 2.7 3 0 0 3 3 3 0 WYL_2, Sm-like SH3 beta-barrel fold DIX PF00778.17 KXH32474.1 - 0.13 12.2 0.1 1.5 8.7 0.0 2.7 3 0 0 3 3 3 0 DIX domain hnRNP_Q_AcD PF18360.1 KXH32474.1 - 0.13 12.2 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 Heterogeneous nuclear ribonucleoprotein Q acidic domain Peptidase_S8 PF00082.22 KXH32476.1 - 5.1e-44 150.7 4.6 2e-42 145.5 5.8 2.2 2 0 0 2 2 2 1 Subtilase family fn3_5 PF06280.12 KXH32476.1 - 8.1e-11 42.6 0.1 1.9e-10 41.4 0.1 1.7 1 0 0 1 1 1 1 Fn3-like domain DUF916 PF06030.12 KXH32476.1 - 0.057 13.5 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF916) WHH PF14414.6 KXH32477.1 - 0.031 14.2 0.0 0.056 13.3 0.0 1.4 1 0 0 1 1 1 0 A nuclease of the HNH/ENDO VII superfamily with conserved WHH Lactamase_B PF00753.27 KXH32478.1 - 1.2e-16 61.3 0.3 2.2e-16 60.4 0.3 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KXH32478.1 - 1.7e-05 24.4 0.8 5.8e-05 22.7 0.1 2.1 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KXH32478.1 - 0.0015 18.5 0.0 0.0045 16.9 0.0 1.8 2 1 0 2 2 2 1 Beta-lactamase superfamily domain FAD_binding_4 PF01565.23 KXH32479.1 - 1.7e-18 66.7 0.6 2.8e-18 66.0 0.6 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KXH32481.1 - 6.9e-05 23.0 0.0 0.0019 18.4 0.1 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXH32481.1 - 0.0064 15.8 0.0 1 8.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 KXH32481.1 - 0.017 15.2 0.0 2 8.5 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.6 KXH32481.1 - 0.023 14.7 0.0 0.48 10.4 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 KXH32481.1 - 0.21 10.8 0.0 9.1 5.4 0.0 2.3 2 0 0 2 2 2 0 FAD binding domain Fungal_trans PF04082.18 KXH32482.1 - 1.4e-10 40.7 0.0 2.3e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.6 KXH32482.1 - 5.4e-05 23.4 3.3 0.0017 18.7 0.1 2.5 2 0 0 2 2 2 1 Zinc-finger double domain zf-met PF12874.7 KXH32482.1 - 0.0004 20.7 0.9 0.0004 20.7 0.9 2.4 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 KXH32482.1 - 0.00048 20.4 2.9 0.00048 20.4 2.9 2.8 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXH32482.1 - 0.0028 18.3 1.3 0.0028 18.3 1.3 3.0 3 0 0 3 3 2 1 C2H2-type zinc finger FYVE PF01363.21 KXH32482.1 - 0.27 11.4 2.6 0.61 10.3 2.6 1.5 1 0 0 1 1 1 0 FYVE zinc finger HypA PF01155.19 KXH32482.1 - 0.32 11.0 1.7 0.74 9.9 1.7 1.5 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-Sec23_Sec24 PF04810.15 KXH32482.1 - 0.32 11.1 0.1 0.32 11.1 0.1 1.8 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger zf-C2H2_jaz PF12171.8 KXH32482.1 - 0.44 10.9 2.5 0.32 11.4 0.4 1.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KXH32482.1 - 0.81 10.1 3.9 0.54 10.6 0.5 2.1 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Prok-RING_1 PF14446.6 KXH32482.1 - 1.8 8.5 4.0 19 5.3 4.0 2.2 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 zf-C2H2_6 PF13912.6 KXH32482.1 - 7.2 6.7 8.4 0.23 11.5 1.8 2.0 2 0 0 2 2 1 0 C2H2-type zinc finger Questin_oxidase PF14027.6 KXH32483.1 - 8.4e-81 272.2 2.0 1e-80 271.8 2.0 1.1 1 0 0 1 1 1 1 Questin oxidase-like GP68 PF17469.2 KXH32483.1 - 0.16 12.4 0.0 0.42 11.1 0.0 1.7 1 0 0 1 1 1 0 Phage protein Gp68 FAD_binding_4 PF01565.23 KXH32484.1 - 8.3e-21 74.2 0.2 1.9e-20 73.0 0.2 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KXH32484.1 - 0.011 15.8 0.6 0.031 14.4 0.0 2.0 2 0 0 2 2 2 0 Berberine and berberine like Pyr_redox_3 PF13738.6 KXH32485.1 - 6.3e-15 55.2 1.5 1.8e-12 47.1 0.3 2.7 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXH32485.1 - 2.8e-12 46.5 0.1 1.7e-08 34.1 0.0 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXH32485.1 - 2.8e-09 36.6 0.3 1.8e-07 30.6 0.1 2.7 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.19 KXH32485.1 - 6.6e-05 21.5 0.1 0.0027 16.2 0.0 2.7 2 1 2 4 4 4 1 Flavin-binding monooxygenase-like Pyr_redox PF00070.27 KXH32485.1 - 0.00014 22.3 0.1 0.013 16.1 0.0 3.4 4 0 0 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXH32485.1 - 0.0078 16.4 0.0 0.022 15.0 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KXH32485.1 - 0.0084 15.4 0.0 0.02 14.1 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.6 KXH32485.1 - 0.046 13.7 0.0 9.8 6.2 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_oxidored PF12831.7 KXH32485.1 - 0.052 12.9 0.0 0.098 12.0 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.19 KXH32485.1 - 0.095 12.1 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 KXH32485.1 - 0.11 11.6 1.9 0.3 10.1 0.2 2.6 3 1 0 3 3 3 0 Lycopene cyclase protein rve_2 PF13333.6 KXH32485.1 - 0.16 12.2 0.1 0.41 10.9 0.1 1.6 1 0 0 1 1 1 0 Integrase core domain Ank_2 PF12796.7 KXH32486.1 - 4.7e-30 104.0 1.2 8.9e-11 42.2 0.0 4.8 1 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXH32486.1 - 6e-23 80.6 5.7 4.6e-07 30.0 0.1 6.4 3 1 2 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXH32486.1 - 4.4e-19 66.6 7.3 0.00026 21.2 0.0 6.8 6 0 0 6 6 6 5 Ankyrin repeat Ank PF00023.30 KXH32486.1 - 3.2e-15 55.8 12.7 0.0019 18.6 0.4 6.9 7 0 0 7 7 7 4 Ankyrin repeat Ank_4 PF13637.6 KXH32486.1 - 3.7e-15 56.1 3.0 3.3e-05 24.3 0.0 5.4 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Phage_tail_2 PF06199.11 KXH32486.1 - 0.03 14.4 0.1 0.14 12.2 0.0 2.2 2 0 0 2 2 2 0 Phage tail tube protein GRP PF07172.11 KXH32488.1 - 0.00077 20.1 1.0 0.0011 19.7 1.0 1.3 1 0 0 1 1 1 1 Glycine rich protein family DAG1 PF05454.11 KXH32488.1 - 0.002 17.5 0.0 0.0028 17.1 0.0 1.3 1 0 0 1 1 1 1 Dystroglycan (Dystrophin-associated glycoprotein 1) DUF2207 PF09972.9 KXH32488.1 - 0.016 14.0 0.0 0.019 13.8 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Herpes_gE PF02480.16 KXH32488.1 - 0.02 13.6 0.1 0.024 13.4 0.1 1.0 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Shisa PF13908.6 KXH32488.1 - 0.025 14.8 0.0 0.032 14.5 0.0 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator RCR PF12273.8 KXH32488.1 - 0.036 14.7 0.1 0.068 13.8 0.1 1.4 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red PsaL PF02605.15 KXH32488.1 - 0.042 13.5 0.0 0.057 13.1 0.0 1.2 1 0 0 1 1 1 0 Photosystem I reaction centre subunit XI Insulin_TMD PF17870.1 KXH32488.1 - 0.053 13.6 0.2 0.094 12.8 0.2 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment SARAF PF06682.12 KXH32488.1 - 0.081 12.6 0.1 0.11 12.1 0.1 1.3 1 1 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis EphA2_TM PF14575.6 KXH32488.1 - 0.11 13.4 0.0 0.13 13.1 0.0 1.2 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain MGC-24 PF05283.11 KXH32488.1 - 0.12 12.8 0.0 0.23 11.9 0.0 1.5 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin FeoB_associated PF12669.7 KXH32488.1 - 1.7 9.1 4.8 2.8 8.4 4.8 1.3 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein FAD_binding_4 PF01565.23 KXH32489.1 - 2.3e-20 72.7 0.5 3.4e-20 72.2 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KXH32489.1 - 0.043 13.9 0.0 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 Berberine and berberine like Sugar_tr PF00083.24 KXH32490.1 - 5.2e-87 292.6 29.7 6.5e-87 292.3 29.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MR_MLE_C PF13378.6 KXH32490.1 - 5.1e-48 163.5 0.1 7.9e-48 162.9 0.1 1.2 1 0 0 1 1 1 1 Enolase C-terminal domain-like MFS_1 PF07690.16 KXH32490.1 - 1.8e-28 99.5 62.3 5e-27 94.7 31.9 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MR_MLE_N PF02746.16 KXH32490.1 - 0.081 13.1 0.0 0.26 11.5 0.0 1.9 2 0 0 2 2 2 0 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain DUF1980 PF09323.10 KXH32490.1 - 0.18 11.7 1.4 0.49 10.3 1.4 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF1980) SepZ PF06066.11 KXH32490.1 - 0.38 11.0 3.2 0.45 10.8 0.4 2.6 2 1 1 3 3 3 0 SepZ DUF1129 PF06570.11 KXH32490.1 - 0.7 9.4 4.8 0.69 9.4 3.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) Sugar_tr PF00083.24 KXH32492.1 - 2.2e-98 330.0 18.1 2.6e-98 329.9 18.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH32492.1 - 2e-39 135.5 38.3 8.1e-33 113.8 19.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KXH32492.1 - 1.3e-07 30.4 9.7 2e-05 23.2 1.7 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Transgly_assoc PF04226.13 KXH32492.1 - 4.2 7.7 12.0 3.4 8.0 0.2 3.4 3 0 0 3 3 3 0 Transglycosylase associated protein 2-Hacid_dh_C PF02826.19 KXH32493.1 - 2.6e-48 163.7 0.1 3.7e-48 163.2 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KXH32493.1 - 1.6e-07 31.0 0.0 2.2e-07 30.6 0.0 1.3 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KXH32493.1 - 0.00015 21.9 0.1 0.00022 21.4 0.1 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase HTH_1 PF00126.27 KXH32493.1 - 0.1 12.5 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family MFS_1 PF07690.16 KXH32494.1 - 5.2e-30 104.6 21.3 2.5e-29 102.3 22.7 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF2776 PF10951.8 KXH32494.1 - 0.0047 16.2 4.1 0.075 12.3 0.0 2.9 3 1 1 4 4 4 2 Protein of unknown function (DUF2776) Trp_oprn_chp PF09534.10 KXH32494.1 - 0.049 13.4 0.1 2.8 7.7 0.0 2.3 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF2304 PF10066.9 KXH32494.1 - 0.17 12.1 1.9 1.8 8.8 0.2 3.0 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2304) M20_dimer PF07687.14 KXH32495.1 - 7.5e-07 29.0 0.4 2.3e-06 27.5 0.1 1.9 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 KXH32495.1 - 1.4e-06 28.2 0.1 2.1e-06 27.6 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 LEA_6 PF10714.9 KXH32495.1 - 0.14 12.2 0.4 0.47 10.6 0.0 2.0 2 0 0 2 2 2 0 Late embryogenesis abundant protein 18 GMC_oxred_N PF00732.19 KXH32497.1 - 4.6e-57 193.7 0.0 6.1e-57 193.2 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXH32497.1 - 8e-31 107.5 0.1 1.2e-30 107.0 0.1 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KXH32497.1 - 0.00077 18.6 0.0 0.0049 16.0 0.0 2.1 3 0 0 3 3 3 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KXH32497.1 - 0.0072 15.6 0.0 0.65 9.2 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXH32497.1 - 0.02 15.1 0.2 0.089 13.0 0.0 2.2 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KXH32497.1 - 0.11 11.5 0.0 2.5 7.1 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain DAO PF01266.24 KXH32497.1 - 0.22 11.1 1.5 1.3 8.6 1.6 2.0 1 1 0 1 1 1 0 FAD dependent oxidoreductase HET PF06985.11 KXH32564.1 - 9.9e-26 90.8 0.0 1.9e-25 89.9 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SdiA-regulated PF06977.11 KXH32564.1 - 0.097 11.9 0.2 0.37 10.0 0.1 1.9 2 0 0 2 2 2 0 SdiA-regulated HATPase_c_3 PF13589.6 KXH32565.1 - 0.00069 19.5 0.0 0.0016 18.3 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Glyco_hydro_61 PF03443.14 KXH32566.1 - 2.8e-44 151.5 0.7 3.8e-44 151.1 0.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Tannase PF07519.11 KXH32567.1 - 8.9e-93 311.7 0.0 1e-92 311.5 0.0 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_1 PF00561.20 KXH32567.1 - 0.0047 16.6 0.0 0.0086 15.7 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KXH32567.1 - 0.024 14.1 0.0 0.92 8.9 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family MFS_1 PF07690.16 KXH32568.1 - 1.2e-22 80.3 24.3 3.2e-22 78.9 22.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DAO PF01266.24 KXH32569.1 - 1.7e-29 103.5 0.0 2.4e-29 103.0 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXH32569.1 - 0.00052 19.3 0.0 0.085 12.1 0.0 2.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXH32569.1 - 0.00056 20.1 0.1 0.0019 18.4 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KXH32569.1 - 0.018 14.3 0.3 0.036 13.3 0.3 1.4 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 KXH32569.1 - 0.031 14.8 0.0 0.079 13.5 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXH32569.1 - 0.056 13.4 0.0 2.1 8.3 0.0 2.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding GIDA PF01134.22 KXH32569.1 - 0.076 12.1 0.0 8.2 5.4 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_Gly3P_dh_N PF01210.23 KXH32569.1 - 0.18 11.8 0.0 0.34 10.9 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus adh_short_C2 PF13561.6 KXH32570.1 - 2.6e-46 158.1 0.0 7.8e-45 153.3 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXH32570.1 - 6.2e-39 133.5 0.0 1.2e-38 132.6 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXH32570.1 - 2.8e-08 33.9 0.1 1.1e-05 25.5 0.1 2.2 1 1 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 KXH32570.1 - 0.024 14.0 0.1 1 8.7 0.0 2.5 3 0 0 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Cys_Met_Meta_PP PF01053.20 KXH32571.1 - 4.6e-122 407.3 0.0 5.2e-122 407.1 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 KXH32571.1 - 5.9e-11 42.3 0.6 1.2e-10 41.2 0.3 1.6 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 KXH32571.1 - 9.2e-07 28.1 0.4 1.4e-06 27.5 0.4 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KXH32571.1 - 1.3e-06 28.0 0.0 1.8e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 KXH32571.1 - 0.00036 19.8 0.0 0.00052 19.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II SepSecS PF05889.13 KXH32571.1 - 0.088 11.5 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Hydrolase_4 PF12146.8 KXH32572.1 - 0.045 13.0 0.0 0.065 12.5 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Fungal_trans PF04082.18 KXH32573.1 - 6.3e-11 41.8 0.0 1.1e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF5470 PF17564.2 KXH32573.1 - 0.016 15.4 0.0 0.049 13.8 0.0 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5470) FAD_binding_4 PF01565.23 KXH32574.1 - 3.4e-23 81.9 0.3 5.8e-23 81.2 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KXH32574.1 - 1 9.5 5.5 1.1 9.4 0.0 3.1 4 0 0 4 4 4 0 Berberine and berberine like GST_N PF02798.20 KXH32576.1 - 8.6e-17 61.2 0.0 1.4e-16 60.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KXH32576.1 - 5.9e-14 52.2 0.0 9.7e-14 51.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KXH32576.1 - 3.6e-11 43.2 0.0 6.1e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KXH32576.1 - 4.8e-07 29.9 0.1 6.6e-07 29.5 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KXH32576.1 - 0.0001 22.4 0.0 0.00016 21.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KXH32576.1 - 0.0028 17.6 0.0 0.0049 16.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_5 PF18485.1 KXH32576.1 - 0.08 13.3 0.0 0.15 12.5 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 KXH32576.1 - 0.12 12.2 0.1 0.24 11.2 0.1 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF1593 PF07632.11 KXH32577.1 - 1.2e-95 319.8 0.0 1.5e-95 319.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1593) Mpv17_PMP22 PF04117.12 KXH32578.1 - 4.3e-12 46.1 7.8 4.4e-12 46.1 5.2 2.1 1 1 1 2 2 2 1 Mpv17 / PMP22 family Sugar_tr PF00083.24 KXH32587.1 - 9.3e-49 166.5 12.0 1.2e-48 166.1 12.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH32587.1 - 2.3e-23 82.7 21.8 4.6e-23 81.7 21.8 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Dak1 PF02733.17 KXH32590.1 - 4.9e-102 341.0 0.0 1.4e-101 339.5 0.0 1.7 2 0 0 2 2 2 1 Dak1 domain Dak2 PF02734.17 KXH32590.1 - 1.7e-36 125.8 1.0 2.9e-36 125.0 1.0 1.4 1 0 0 1 1 1 1 DAK2 domain Fungal_trans_2 PF11951.8 KXH32591.1 - 2e-13 50.0 0.1 1.3e-10 40.7 0.0 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH32591.1 - 3.3e-07 30.3 7.2 7.4e-07 29.2 7.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain F_bP_aldolase PF01116.20 KXH32592.1 - 1.7e-82 277.1 0.4 1.9e-82 276.9 0.4 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II CobS PF02654.15 KXH32592.1 - 0.049 13.8 0.8 0.26 11.4 0.0 2.0 2 0 0 2 2 2 0 Cobalamin-5-phosphate synthase LacAB_rpiB PF02502.18 KXH32593.1 - 2.2e-45 154.1 0.0 2.5e-45 153.9 0.0 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase p450 PF00067.22 KXH32594.1 - 7.7e-37 127.1 0.0 1.2e-36 126.5 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 adh_short_C2 PF13561.6 KXH32595.1 - 5.9e-53 179.8 0.0 7.4e-53 179.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXH32595.1 - 1e-45 155.6 0.1 1.3e-45 155.2 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXH32595.1 - 4.7e-09 36.4 0.1 6.7e-09 35.9 0.1 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KXH32595.1 - 0.012 14.8 0.0 0.015 14.4 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Epimerase PF01370.21 KXH32595.1 - 0.021 14.3 0.0 0.034 13.6 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family MFS_1 PF07690.16 KXH32596.1 - 1.6e-35 122.7 32.4 1.6e-35 122.7 32.4 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH32596.1 - 1.1e-13 50.8 20.3 1.6e-13 50.4 20.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter Dynamin_N PF00350.23 KXH32597.1 - 8.3e-33 113.8 0.0 1.8e-32 112.7 0.0 1.6 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 KXH32597.1 - 1.4e-19 70.4 0.0 3.3e-17 62.6 0.0 2.4 2 0 0 2 2 2 2 Dynamin central region GED PF02212.18 KXH32597.1 - 6.4e-05 23.0 0.3 6.4e-05 23.0 0.3 2.1 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KXH32597.1 - 0.0003 20.9 0.5 0.012 15.7 0.5 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KXH32597.1 - 0.0016 18.0 0.1 2.1 7.9 0.1 2.5 2 0 0 2 2 2 2 Ferrous iron transport protein B AAA_16 PF13191.6 KXH32597.1 - 0.065 13.6 0.1 0.44 10.9 0.0 2.3 2 1 0 2 2 2 0 AAA ATPase domain DUF3987 PF13148.6 KXH32597.1 - 0.092 11.7 0.0 0.26 10.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) VASt PF16016.5 KXH32598.1 - 1.6e-37 129.2 0.0 2.8e-37 128.5 0.0 1.4 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 KXH32598.1 - 4.3e-24 84.6 0.0 6.8e-24 83.9 0.0 1.3 1 0 0 1 1 1 1 GRAM domain bZIP_1 PF00170.21 KXH32599.1 - 0.0079 16.3 13.5 0.34 11.0 6.8 2.8 2 1 0 2 2 2 2 bZIP transcription factor Clr5 PF14420.6 KXH32599.1 - 0.025 14.8 0.6 0.053 13.7 0.0 1.8 2 0 0 2 2 1 0 Clr5 domain DUF2046 PF09755.9 KXH32599.1 - 0.037 13.3 4.9 0.11 11.7 0.6 2.5 3 0 0 3 3 3 0 Uncharacterized conserved protein H4 (DUF2046) BLOC1_2 PF10046.9 KXH32599.1 - 0.079 13.3 4.8 0.43 10.9 1.0 2.6 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Herpes_UL6 PF01763.16 KXH32599.1 - 0.46 8.9 2.1 0.51 8.8 0.9 1.6 1 1 1 2 2 2 0 Herpesvirus UL6 like KASH_CCD PF14662.6 KXH32599.1 - 0.5 10.2 10.0 1.1 9.0 2.8 2.5 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH CENP-Q PF13094.6 KXH32599.1 - 0.61 10.3 19.9 0.037 14.2 6.0 3.8 4 0 0 4 4 3 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF4446 PF14584.6 KXH32599.1 - 0.83 9.6 3.3 8.2 6.4 1.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) KxDL PF10241.9 KXH32599.1 - 1.1 9.6 7.7 0.73 10.2 1.6 2.7 2 0 0 2 2 2 0 Uncharacterized conserved protein Cep57_CLD_2 PF14197.6 KXH32599.1 - 1.3 9.1 9.1 0.18 11.9 3.1 2.4 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 GAS PF13851.6 KXH32599.1 - 1.5 8.2 15.0 0.73 9.2 7.4 2.4 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Ax_dynein_light PF10211.9 KXH32599.1 - 1.8 8.5 10.3 2 8.3 4.1 2.5 2 0 0 2 2 2 0 Axonemal dynein light chain Prefoldin_2 PF01920.20 KXH32599.1 - 2.2 8.3 10.9 10 6.1 4.2 2.6 2 0 0 2 2 2 0 Prefoldin subunit Rootletin PF15035.6 KXH32599.1 - 7.3 6.6 15.8 0.61 10.1 2.7 3.2 3 0 0 3 3 3 0 Ciliary rootlet component, centrosome cohesion DUF373 PF04123.13 KXH32684.1 - 0.003 17.1 5.8 0.003 17.1 5.8 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF373) Oxidored_q3 PF00499.20 KXH32684.1 - 5.8 6.6 13.6 1e+03 -0.6 13.6 3.3 1 1 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 4HBT PF03061.22 KXH32685.1 - 2.5e-13 50.2 0.0 3.6e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.6 KXH32685.1 - 0.0058 16.8 0.0 0.0078 16.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4442) 4HBT_3 PF13622.6 KXH32685.1 - 0.16 12.2 0.0 0.17 12.1 0.0 1.1 1 0 0 1 1 1 0 Thioesterase-like superfamily Tfb2 PF03849.14 KXH32686.1 - 2.3e-134 447.9 0.0 2.7e-134 447.6 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 KXH32686.1 - 2.2e-21 76.0 0.1 4.2e-21 75.1 0.1 1.5 1 0 0 1 1 1 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 KXH32686.1 - 7.3e-05 22.9 0.0 0.00017 21.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain TANGO2 PF05742.12 KXH32688.1 - 2.2e-69 234.3 0.0 2.6e-69 234.1 0.0 1.0 1 0 0 1 1 1 1 Transport and Golgi organisation 2 ABC_tran PF00005.27 KXH32689.1 - 9.2e-40 136.3 0.0 2.2e-18 67.1 0.0 2.8 3 0 0 3 3 2 2 ABC transporter ABC_membrane PF00664.23 KXH32689.1 - 2.2e-23 83.3 39.5 8.7e-23 81.3 14.6 3.2 3 1 0 3 3 3 2 ABC transporter transmembrane region AAA_21 PF13304.6 KXH32689.1 - 1.4e-10 41.5 3.4 0.00013 21.9 0.1 4.2 2 2 2 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KXH32689.1 - 7e-08 32.2 0.0 0.0058 16.1 0.0 3.9 3 1 0 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KXH32689.1 - 6.3e-06 25.8 0.1 0.13 12.0 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KXH32689.1 - 5.3e-05 23.2 0.1 0.41 10.5 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 KXH32689.1 - 8e-05 22.9 0.0 0.29 11.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KXH32689.1 - 0.00076 19.9 0.1 1.1 9.6 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 KXH32689.1 - 0.0018 18.3 0.1 1.2 9.2 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_7 PF12775.7 KXH32689.1 - 0.0036 16.8 0.0 0.52 9.8 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA PF00004.29 KXH32689.1 - 0.0064 16.9 0.0 2.7 8.4 0.0 3.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 KXH32689.1 - 0.0072 15.4 0.0 0.21 10.6 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_18 PF13238.6 KXH32689.1 - 0.018 15.6 0.0 4.6 7.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KXH32689.1 - 0.018 15.2 0.0 1.1 9.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 KXH32689.1 - 0.029 14.4 0.4 5.4 7.0 0.1 2.4 2 0 0 2 2 2 0 Dynamin family AAA_15 PF13175.6 KXH32689.1 - 0.033 13.9 0.0 4.2 7.0 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.6 KXH32689.1 - 0.048 14.2 0.0 6.6 7.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 KXH32689.1 - 0.051 13.1 0.2 8.1 6.0 0.1 2.6 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 KXH32689.1 - 0.21 11.6 0.1 1 9.4 0.0 1.9 2 0 0 2 2 2 0 Helicase HerA, central domain PfkB PF00294.24 KXH32690.1 - 1.2e-13 51.0 0.0 1.7e-13 50.6 0.0 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 KXH32690.1 - 0.098 12.0 0.0 0.23 10.8 0.0 1.6 2 0 0 2 2 2 0 Phosphomethylpyrimidine kinase PfkB PF00294.24 KXH32691.1 - 8.7e-40 136.9 0.1 1e-39 136.7 0.1 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 KXH32691.1 - 0.013 14.9 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase Peptidase_S8 PF00082.22 KXH32692.1 - 1e-45 156.3 4.4 1.7e-45 155.6 4.4 1.3 1 0 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 KXH32692.1 - 1.5e-06 28.8 0.9 1.1e-05 26.1 0.0 2.4 2 0 0 2 2 2 1 Fn3-like domain PA PF02225.22 KXH32692.1 - 5.8e-05 23.0 0.0 0.0002 21.3 0.0 1.9 1 0 0 1 1 1 1 PA domain DUF4232 PF14016.6 KXH32692.1 - 0.029 14.5 1.8 0.093 12.9 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4232) Fungal_trans_2 PF11951.8 KXH32694.1 - 2e-08 33.5 0.1 2.8e-08 33.0 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain CVNH PF08881.10 KXH32695.1 - 5.2e-09 36.7 0.3 7.8e-09 36.1 0.3 1.3 1 1 0 1 1 1 1 CVNH domain CFEM PF05730.11 KXH32696.1 - 7.2e-13 48.4 13.0 1.2e-12 47.8 13.0 1.3 1 0 0 1 1 1 1 CFEM domain Gamma-thionin PF00304.20 KXH32696.1 - 0.54 10.6 5.3 0.15 12.4 1.9 1.8 2 0 0 2 2 2 0 Gamma-thionin family FAD_binding_3 PF01494.19 KXH32697.1 - 8.2e-21 74.6 0.0 1.6e-20 73.6 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KXH32697.1 - 4.1e-10 39.8 1.1 1e-08 35.2 1.0 2.0 1 1 1 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXH32697.1 - 8.8e-09 35.0 0.0 2.2e-05 23.8 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXH32697.1 - 7.7e-06 26.1 0.2 1.7e-05 25.0 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KXH32697.1 - 0.00018 20.9 0.0 0.05 12.9 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.12 KXH32697.1 - 0.00067 18.8 0.2 0.59 9.1 0.0 2.6 3 0 0 3 3 3 2 Lycopene cyclase protein GIDA PF01134.22 KXH32697.1 - 0.0034 16.5 0.0 0.0049 16.0 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 KXH32697.1 - 0.004 16.3 1.1 0.0055 15.8 1.1 1.2 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.14 KXH32697.1 - 0.0067 15.3 0.4 0.1 11.4 0.2 2.1 2 0 0 2 2 2 1 Tryptophan halogenase AlaDh_PNT_C PF01262.21 KXH32697.1 - 0.01 15.2 0.4 0.018 14.3 0.4 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 KXH32697.1 - 0.014 15.9 0.0 0.11 13.1 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXH32697.1 - 0.032 14.2 0.7 1.1 9.2 0.2 2.9 2 1 1 3 3 3 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 KXH32697.1 - 0.034 13.4 0.0 0.96 8.6 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXH32697.1 - 0.036 12.8 0.6 0.058 12.1 0.6 1.3 1 0 0 1 1 1 0 HI0933-like protein SE PF08491.10 KXH32697.1 - 0.11 11.5 0.0 4.7 6.2 0.0 2.2 2 0 0 2 2 2 0 Squalene epoxidase Thi4 PF01946.17 KXH32697.1 - 0.12 11.6 0.2 0.2 10.9 0.2 1.4 1 0 0 1 1 1 0 Thi4 family Fungal_trans PF04082.18 KXH32698.1 - 9.5e-06 24.8 0.2 1.6e-05 24.1 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short_C2 PF13561.6 KXH32699.1 - 2.1e-51 174.7 0.0 2.7e-51 174.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXH32699.1 - 2.2e-46 157.8 0.0 2.6e-46 157.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXH32699.1 - 8e-07 29.1 0.0 1.1e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXH32699.1 - 0.00014 21.5 0.0 0.00035 20.1 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 KXH32699.1 - 0.052 12.9 0.0 0.072 12.5 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Beta-lactamase PF00144.24 KXH32700.1 - 3.6e-41 141.5 0.0 5.4e-41 140.9 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Clr5 PF14420.6 KXH32701.1 - 0.095 12.9 0.4 0.38 11.0 0.4 2.0 1 1 0 1 1 1 0 Clr5 domain Lipase_GDSL_2 PF13472.6 KXH32703.1 - 7.8e-09 36.2 0.0 9.6e-09 35.9 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KXH32703.1 - 0.0056 16.7 0.0 0.16 11.9 0.0 2.2 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 KXH32703.1 - 0.033 14.3 0.0 0.056 13.6 0.0 1.4 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family RRM_1 PF00076.22 KXH32704.1 - 1.8e-16 59.7 0.0 1.7e-09 37.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SPOR PF05036.13 KXH32704.1 - 0.052 13.9 0.1 2.9 8.3 0.0 2.5 2 0 0 2 2 2 0 Sporulation related domain Cytochrom_B561 PF03188.16 KXH32706.1 - 0.062 13.4 1.7 0.24 11.6 0.2 2.3 2 0 0 2 2 2 0 Eukaryotic cytochrome b561 Serpentine_r_xa PF03383.15 KXH32706.1 - 1.2 9.1 10.6 0.16 12.0 5.4 2.1 1 1 1 2 2 2 0 Caenorhabditis serpentine receptor-like protein, class xa Abhydrolase_6 PF12697.7 KXH32707.1 - 6.9e-12 46.4 0.1 6.5e-11 43.3 0.1 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXH32707.1 - 3e-05 23.4 0.0 0.016 14.5 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KXH32707.1 - 8.4e-05 22.3 0.0 0.00023 20.9 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KXH32707.1 - 0.00063 19.3 0.1 5.2 6.5 0.0 3.7 3 1 1 4 4 4 2 Prolyl oligopeptidase family Peptidase_M1_N PF17900.1 KXH32707.1 - 0.0028 17.8 0.0 0.0045 17.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain FSH1 PF03959.13 KXH32707.1 - 0.032 13.9 0.0 0.085 12.5 0.0 1.6 1 1 0 1 1 1 0 Serine hydrolase (FSH1) TPP_enzyme_N PF02776.18 KXH32707.1 - 0.1 12.2 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain AATase PF07247.12 KXH32708.1 - 5.2e-12 45.1 0.0 2.6e-11 42.8 0.0 2.0 3 0 0 3 3 3 1 Alcohol acetyltransferase WW_like PF17890.1 KXH32708.1 - 0.074 13.1 0.0 0.23 11.5 0.0 1.8 1 0 0 1 1 1 0 Peptidoglycan hydrolase LytB WW-like domain Prok-RING_2 PF14445.6 KXH32712.1 - 0.086 13.0 0.1 9.9 6.4 0.1 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 2 Peptidase_M16_M PF16187.5 KXH32713.1 - 2.8e-55 187.6 2.2 7.6e-55 186.2 2.2 1.7 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16_C PF05193.21 KXH32713.1 - 1.1e-21 77.7 0.2 1.1e-10 41.9 0.1 3.4 2 1 1 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KXH32713.1 - 1.5e-19 70.4 0.2 4.4e-17 62.4 0.2 3.0 1 1 0 1 1 1 1 Insulinase (Peptidase family M16) Herpes_UL74 PF07982.12 KXH32713.1 - 0.073 12.0 0.0 0.15 11.0 0.0 1.4 1 0 0 1 1 1 0 Herpes UL74 glycoproteins HCMVantigenic_N PF12154.8 KXH32717.1 - 2.5 8.3 6.8 34 4.6 0.2 3.3 2 0 0 2 2 2 0 Glycoprotein B N-terminal antigenic domain of HCMV Pkinase PF00069.25 KXH32719.1 - 7.6e-10 38.6 0.0 9.7e-10 38.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXH32719.1 - 5.3e-09 35.7 0.0 2e-08 33.8 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KXH32719.1 - 0.00023 20.6 0.0 0.00032 20.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXH32719.1 - 0.0016 18.5 0.0 0.0024 17.8 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KXH32719.1 - 0.0069 15.7 0.0 0.0097 15.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KXH32719.1 - 0.031 13.9 0.0 0.073 12.7 0.0 1.5 1 1 0 1 1 1 0 RIO1 family DENN PF02141.21 KXH32720.1 - 7.8e-40 136.8 0.1 1.3e-39 136.0 0.1 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 KXH32720.1 - 4.4e-07 30.6 0.3 2.8e-06 28.0 0.0 2.4 2 0 0 2 2 2 1 uDENN domain Elongin_A PF06881.11 KXH32720.1 - 0.0054 17.2 6.7 0.025 15.1 6.7 2.1 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A IFT57 PF10498.9 KXH32720.1 - 0.0063 15.5 5.6 0.0063 15.5 5.6 2.3 2 1 1 3 3 3 1 Intra-flagellar transport protein 57 DUF5345 PF17280.2 KXH32720.1 - 0.26 11.3 0.8 0.82 9.7 0.8 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5345) TMF_TATA_bd PF12325.8 KXH32720.1 - 4.1 7.7 15.6 5.3 7.3 3.8 2.7 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding zf-HIT PF04438.16 KXH32721.1 - 4.9e-09 35.9 9.1 7e-09 35.4 9.1 1.2 1 0 0 1 1 1 1 HIT zinc finger MPP6 PF10175.9 KXH32721.1 - 0.12 12.9 4.1 0.28 11.7 4.1 1.6 1 0 0 1 1 1 0 M-phase phosphoprotein 6 DUF3435 PF11917.8 KXH32724.1 - 1.1e-66 225.5 2.6 4e-66 223.7 0.4 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3435) LRR_8 PF13855.6 KXH32859.1 - 8.3e-13 47.9 5.5 6.2e-08 32.3 2.9 3.3 1 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 KXH32859.1 - 1.1e-12 47.9 2.6 0.00046 20.5 0.8 3.6 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KXH32859.1 - 6e-05 23.1 6.1 22 6.1 0.2 5.7 4 2 0 4 4 4 2 Leucine Rich Repeat LRR_9 PF14580.6 KXH32859.1 - 0.002 17.6 0.5 0.0065 16.0 0.3 1.8 1 1 1 2 2 2 1 Leucine-rich repeat LRR_6 PF13516.6 KXH32859.1 - 0.025 14.6 11.1 14 6.1 0.0 5.2 5 0 0 5 5 5 0 Leucine Rich repeat NAD_binding_5 PF07994.12 KXH32960.1 - 5.1e-144 479.6 0.0 6e-144 479.3 0.0 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 KXH32960.1 - 1.7e-45 153.7 0.6 3.7e-45 152.6 0.6 1.6 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase CDH-cyt PF16010.5 KXH32961.1 - 2.3e-21 76.3 0.2 4.3e-21 75.4 0.2 1.4 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase Cytochrom_B561 PF03188.16 KXH32961.1 - 5.4e-09 36.3 10.0 1.2e-08 35.2 10.0 1.6 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF2427 PF10348.9 KXH32961.1 - 0.00015 21.5 1.1 0.00015 21.5 1.1 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) DOMON PF03351.17 KXH32961.1 - 0.0016 18.7 0.6 0.019 15.2 0.2 2.5 1 1 1 2 2 2 1 DOMON domain Pox_P21 PF05313.12 KXH32961.1 - 0.067 12.8 0.3 0.44 10.1 0.0 2.0 2 0 0 2 2 2 0 Poxvirus P21 membrane protein DUF2207 PF09972.9 KXH32961.1 - 0.073 11.8 6.5 11 4.7 6.5 2.1 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4079 PF13301.6 KXH32961.1 - 0.078 13.1 10.0 0.71 10.0 7.3 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF4079) DUF2157 PF09925.9 KXH32961.1 - 0.31 10.8 10.9 1.5 8.6 11.0 2.0 1 1 0 1 1 1 0 Predicted membrane protein (DUF2157) DUF3309 PF11752.8 KXH32961.1 - 0.55 10.3 5.3 0.94 9.6 3.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3309) DUF4231 PF14015.6 KXH32961.1 - 0.69 10.4 7.0 0.34 11.4 0.8 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF4231) DUF2306 PF10067.9 KXH32961.1 - 1.2 9.4 8.3 0.67 10.2 1.7 2.5 1 1 1 2 2 2 0 Predicted membrane protein (DUF2306) RseC_MucC PF04246.12 KXH32961.1 - 6 6.8 8.9 0.29 11.1 2.1 2.3 2 1 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC MFS_1 PF07690.16 KXH32962.1 - 2.8e-28 98.9 24.1 2.8e-28 98.9 24.1 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH32962.1 - 0.0018 17.2 7.5 0.0072 15.2 7.3 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter Ctr PF04145.15 KXH32962.1 - 0.16 12.6 0.6 12 6.5 0.1 2.8 2 1 0 2 2 2 0 Ctr copper transporter family MFS_1_like PF12832.7 KXH32962.1 - 0.18 10.6 8.6 0.2 10.5 2.4 2.8 2 1 1 3 3 3 0 MFS_1 like family MFS_3 PF05977.13 KXH32962.1 - 5.3 5.3 9.1 0.18 10.1 1.7 2.0 2 1 0 2 2 2 0 Transmembrane secretion effector Peptidase_S8 PF00082.22 KXH32964.1 - 1.2e-50 172.5 0.2 2.9e-50 171.2 0.2 1.6 2 0 0 2 2 2 1 Subtilase family fn3_5 PF06280.12 KXH32964.1 - 2.9e-10 40.9 0.1 6.5e-10 39.7 0.1 1.6 1 0 0 1 1 1 1 Fn3-like domain FlgD_ig PF13860.6 KXH32964.1 - 0.0065 16.3 0.0 0.19 11.6 0.0 3.2 3 1 0 3 3 3 1 FlgD Ig-like domain Inhibitor_I9 PF05922.16 KXH32964.1 - 0.09 13.5 0.0 0.23 12.2 0.0 1.7 1 0 0 1 1 1 0 Peptidase inhibitor I9 tRNA-synt_2b PF00587.25 KXH32965.1 - 1.1e-37 129.7 0.0 1.7e-37 129.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 KXH32965.1 - 2.3e-18 66.4 7.4 4.4e-18 65.5 7.4 1.5 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Vfa1 PF08432.10 KXH32965.1 - 0.69 10.2 8.6 1.2 9.4 8.6 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 SHNi-TPR PF10516.9 KXH32966.1 - 7.2e-15 54.2 0.3 7.2e-15 54.2 0.3 2.5 3 0 0 3 3 3 1 SHNi-TPR TPR_12 PF13424.6 KXH32966.1 - 1.6e-09 37.9 0.4 0.00034 20.9 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 KXH32966.1 - 9.8e-05 22.0 2.3 0.00068 19.4 0.4 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 KXH32966.1 - 0.00048 20.0 9.8 0.00081 19.3 0.2 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat UPF0227 PF05728.12 KXH32966.1 - 0.062 13.2 0.1 0.79 9.6 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) TPR_10 PF13374.6 KXH32966.1 - 0.33 10.9 2.2 21 5.1 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF2508 PF10704.9 KXH32966.1 - 0.43 10.8 8.6 4.7 7.5 0.2 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF2508) TPR_8 PF13181.6 KXH32966.1 - 3.7 8.0 10.6 0.27 11.6 0.4 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat RabGAP-TBC PF00566.18 KXH32967.1 - 1.9e-38 132.3 0.0 7.4e-38 130.4 0.0 2.0 1 1 0 1 1 1 1 Rab-GTPase-TBC domain RRM_1 PF00076.22 KXH32969.1 - 7.2e-35 118.6 0.2 1.2e-16 60.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KXH32969.1 - 1.3e-11 44.5 0.1 6.9e-05 22.9 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 KXH32969.1 - 0.00016 21.6 0.0 0.48 10.5 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 KXH32969.1 - 0.2 11.7 1.5 13 5.9 0.0 2.7 3 0 0 3 3 3 0 RNA binding motif DUF4175 PF13779.6 KXH32969.1 - 0.82 7.5 34.5 1.2 7.0 34.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) TFIIA PF03153.13 KXH32969.1 - 1.3 8.9 21.6 1.8 8.5 21.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF1631 PF07793.11 KXH32969.1 - 2.4 6.5 14.5 3.9 5.8 14.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) GCS PF03074.16 KXH32970.1 - 2.1e-172 573.5 0.0 2.6e-172 573.3 0.0 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase GATA PF00320.27 KXH32972.1 - 4.5e-16 58.2 3.5 7.3e-16 57.5 3.5 1.3 1 0 0 1 1 1 1 GATA zinc finger Perilipin PF03036.16 KXH32972.1 - 0.12 11.4 0.0 0.16 10.9 0.0 1.1 1 0 0 1 1 1 0 Perilipin family Ribosomal_S5_C PF03719.15 KXH32972.1 - 0.14 11.6 0.0 0.43 10.1 0.0 1.7 1 0 0 1 1 1 0 Ribosomal protein S5, C-terminal domain ORMDL PF04061.14 KXH32974.1 - 3.9e-58 195.1 2.6 5.2e-58 194.7 2.6 1.2 1 0 0 1 1 1 1 ORMDL family FAM76 PF16046.5 KXH32978.1 - 0.18 11.2 4.1 0.28 10.5 4.1 1.2 1 0 0 1 1 1 0 FAM76 protein baeRF_family5 PF18846.1 KXH33132.1 - 0.15 12.3 0.0 0.27 11.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 5 DUF3435 PF11917.8 KXH33133.1 - 1.3e-19 70.4 0.0 2.2e-19 69.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) Chromo PF00385.24 KXH33133.1 - 0.0034 17.3 0.0 1.5 8.8 0.0 2.9 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain zf-Di19 PF05605.12 KXH33133.1 - 0.73 10.2 5.7 0.89 9.9 0.9 2.9 1 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 KXH33133.1 - 3.8 8.0 6.6 1 9.9 0.5 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KXH33133.1 - 9.7 6.6 7.9 39 4.7 0.3 2.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding DUF2961 PF11175.8 KXH33134.1 - 6e-76 255.2 2.5 5.5e-68 229.1 2.1 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2961) F-box-like PF12937.7 KXH33136.1 - 4.7e-06 26.4 0.1 6.5e-05 22.7 0.1 2.6 1 1 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KXH33136.1 - 0.095 13.2 0.0 30 5.2 0.0 3.5 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) Steroid_dh PF02544.16 KXH33137.1 - 1.5e-16 60.7 2.3 2.5e-14 53.5 2.3 2.3 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 KXH33137.1 - 0.00045 19.8 0.2 0.00085 18.9 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) MINDY_DUB PF04424.13 KXH33138.1 - 7.2e-24 84.1 0.0 1.2e-23 83.4 0.0 1.3 1 0 0 1 1 1 1 MINDY deubiquitinase PhoLip_ATPase_C PF16212.5 KXH33140.1 - 1.6e-76 257.4 27.5 1.6e-76 257.4 27.5 2.4 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KXH33140.1 - 5e-20 70.9 0.7 1.5e-19 69.4 0.7 1.8 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 KXH33140.1 - 1.6e-12 47.3 0.2 7.9e-12 45.1 0.0 2.2 3 0 0 3 3 3 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KXH33140.1 - 2.8e-12 47.4 2.0 1.8e-07 31.7 0.2 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KXH33140.1 - 0.0015 18.1 0.2 0.0072 15.9 0.0 2.3 3 1 0 3 3 3 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KXH33140.1 - 0.0033 17.2 0.9 0.0086 15.8 0.9 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Aldedh PF00171.22 KXH33141.1 - 2.4e-116 389.0 0.0 3e-116 388.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DEAD PF00270.29 KXH33142.1 - 6.1e-35 120.6 0.0 9.1e-35 120.0 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXH33142.1 - 3.8e-27 94.8 0.0 1.3e-26 93.2 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 KXH33142.1 - 0.15 10.8 0.0 0.18 10.5 0.0 1.1 1 0 0 1 1 1 0 SNF2 family N-terminal domain Ipi1_N PF12333.8 KXH33143.1 - 1.3e-29 102.8 2.4 1.8e-29 102.3 0.1 2.2 2 0 0 2 2 2 1 Rix1 complex component involved in 60S ribosome maturation TPR_20 PF14561.6 KXH33143.1 - 0.014 15.7 0.1 0.032 14.5 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF5542 PF17696.1 KXH33144.1 - 0.024 14.8 0.1 0.036 14.2 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5542) Robl_LC7 PF03259.17 KXH33144.1 - 0.13 12.0 0.0 0.36 10.6 0.0 1.7 2 0 0 2 2 2 0 Roadblock/LC7 domain LAMTOR5 PF16672.5 KXH33144.1 - 0.14 12.1 0.0 0.33 10.9 0.0 1.5 2 0 0 2 2 2 0 Ragulator complex protein LAMTOR5 Pyrid_oxidase_2 PF13883.6 KXH33147.1 - 2e-40 138.6 0.0 2.7e-40 138.1 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase F-box-like PF12937.7 KXH33148.1 - 0.081 12.8 0.0 0.27 11.2 0.0 2.0 1 0 0 1 1 1 0 F-box-like Ribosomal_S30 PF04758.14 KXH33149.1 - 1.2e-29 102.3 8.0 1.3e-29 102.1 8.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 Fungal_trans PF04082.18 KXH33150.1 - 2.8e-11 42.9 1.4 4.7e-11 42.2 1.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH33150.1 - 0.045 13.9 2.0 0.08 13.1 2.0 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Cytochrome_C7 PF14522.6 KXH33151.1 - 0.0068 16.4 3.0 0.0083 16.1 3.0 1.1 1 0 0 1 1 1 1 Cytochrome c7 and related cytochrome c Gmx_para_CXXCG PF09535.10 KXH33151.1 - 0.014 14.6 3.4 0.39 9.9 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (Gmx_para_CXXCG) DUF2256 PF10013.9 KXH33151.1 - 1.6 8.9 7.1 9.3 6.5 0.3 3.1 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) Spb1_C PF07780.12 KXH33383.1 - 5.6e-86 287.5 21.1 5.6e-86 287.5 21.1 4.2 4 1 0 4 4 4 1 Spb1 C-terminal domain FtsJ PF01728.19 KXH33383.1 - 5.2e-57 192.8 0.0 8.7e-57 192.1 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.8 KXH33383.1 - 1.1e-51 174.9 15.1 1.1e-51 174.9 15.1 5.1 3 1 0 3 3 3 1 Domain of unknown function (DUF3381) Methyltransf_23 PF13489.6 KXH33383.1 - 0.0028 17.5 0.1 0.013 15.4 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain WD40 PF00400.32 KXH33384.1 - 1.3e-13 51.2 1.2 0.033 15.0 0.0 6.5 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXH33384.1 - 4.2e-05 23.8 0.0 0.65 10.3 0.0 4.3 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KXH33384.1 - 0.19 10.7 0.0 1.5 7.7 0.0 2.5 4 0 0 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Heme_oxygenase PF01126.20 KXH33385.1 - 3.6e-06 26.9 0.0 2.4e-05 24.2 0.0 2.0 2 0 0 2 2 2 1 Heme oxygenase EamA PF00892.20 KXH33386.1 - 2.7e-11 43.8 35.9 3.1e-05 24.2 4.4 3.1 3 0 0 3 3 3 3 EamA-like transporter family DUF3955 PF13127.6 KXH33386.1 - 4.5e-09 36.0 1.6 4.5e-09 36.0 1.6 3.1 3 0 0 3 3 3 1 Protein of unknown function (DUF3955) PUNUT PF16913.5 KXH33386.1 - 2e-07 30.5 3.9 2e-07 30.5 3.9 2.4 2 1 1 3 3 3 1 Purine nucleobase transmembrane transport SLC35F PF06027.12 KXH33386.1 - 7.5e-05 22.4 13.8 7.5e-05 22.4 13.8 1.9 2 0 0 2 2 2 1 Solute carrier family 35 UAA PF08449.11 KXH33386.1 - 0.00077 18.8 12.5 0.00077 18.8 12.5 1.5 2 0 0 2 2 2 1 UAA transporter family Brr6_like_C_C PF10104.9 KXH33386.1 - 0.56 10.0 0.0 0.56 10.0 0.0 3.0 3 0 0 3 3 3 0 Di-sulfide bridge nucleocytoplasmic transport domain Ras PF00071.22 KXH33387.1 - 6.8e-57 191.6 0.0 8e-57 191.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXH33387.1 - 4.6e-32 110.7 0.0 6.6e-32 110.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXH33387.1 - 5.7e-13 48.7 0.0 6.8e-13 48.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KXH33387.1 - 5e-08 33.0 0.0 8.2e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KXH33387.1 - 4.6e-06 26.2 0.0 5.6e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KXH33387.1 - 5e-05 22.9 0.0 0.0017 18.0 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KXH33387.1 - 0.00016 21.7 0.1 0.0038 17.2 0.1 2.4 1 1 2 3 3 3 1 RsgA GTPase SRPRB PF09439.10 KXH33387.1 - 0.002 17.6 0.0 0.0027 17.2 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_5 PF07728.14 KXH33387.1 - 0.0044 17.0 0.0 0.0067 16.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KXH33387.1 - 0.0086 16.5 0.0 0.014 15.8 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain PduV-EutP PF10662.9 KXH33387.1 - 0.0095 15.7 0.1 0.13 12.0 0.0 2.1 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 KXH33387.1 - 0.0098 16.2 0.0 0.016 15.5 0.0 1.4 1 1 0 1 1 1 1 AAA domain ATP_bind_1 PF03029.17 KXH33387.1 - 0.013 15.3 0.2 0.36 10.6 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_24 PF13479.6 KXH33387.1 - 0.02 14.6 0.0 0.042 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Septin PF00735.18 KXH33387.1 - 0.021 14.1 0.1 0.048 12.9 0.0 1.6 2 0 0 2 2 2 0 Septin AAA_7 PF12775.7 KXH33387.1 - 0.024 14.1 0.1 0.041 13.4 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region NB-ARC PF00931.22 KXH33387.1 - 0.026 13.7 0.1 0.29 10.3 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain cobW PF02492.19 KXH33387.1 - 0.044 13.4 0.0 0.096 12.3 0.0 1.6 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ATPase_2 PF01637.18 KXH33387.1 - 0.07 13.0 0.2 0.13 12.1 0.0 1.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea NTPase_1 PF03266.15 KXH33387.1 - 0.097 12.6 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 NTPase TniB PF05621.11 KXH33387.1 - 0.12 11.8 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein NACHT PF05729.12 KXH33387.1 - 0.12 12.2 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_lid_2 PF17863.1 KXH33388.1 - 1.8e-05 24.5 0.2 4.2e-05 23.3 0.2 1.7 1 0 0 1 1 1 1 AAA lid domain AAA_3 PF07726.11 KXH33388.1 - 0.07 13.0 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) GDA1_CD39 PF01150.17 KXH33389.1 - 1.3e-104 350.3 0.0 1.6e-104 349.9 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.16 KXH33389.1 - 0.018 14.5 0.0 0.031 13.7 0.0 1.3 1 0 0 1 1 1 0 Ppx/GppA phosphatase family Kinesin PF00225.23 KXH33390.1 - 2.2e-113 378.6 0.0 3.3e-113 378.0 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain PUL PF08324.11 KXH33390.1 - 2.4e-63 214.0 0.2 4.1e-63 213.2 0.2 1.3 1 0 0 1 1 1 1 PUL domain Peptidase_C97 PF05903.14 KXH33390.1 - 5.8e-34 117.1 0.0 1.1e-33 116.1 0.0 1.5 1 0 0 1 1 1 1 PPPDE putative peptidase domain Microtub_bd PF16796.5 KXH33390.1 - 9.5e-26 90.5 0.0 2.2e-25 89.3 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding Thioredoxin PF00085.20 KXH33390.1 - 9e-11 41.7 0.0 2e-10 40.5 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin TraF PF13728.6 KXH33390.1 - 7.5e-05 22.7 0.0 0.00028 20.8 0.0 1.9 1 0 0 1 1 1 1 F plasmid transfer operon protein DUF1087 PF06465.13 KXH33390.1 - 0.0087 16.1 0.1 0.024 14.7 0.1 1.8 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1087) PriC PF07445.12 KXH33390.1 - 0.029 14.3 5.6 0.07 13.1 5.6 1.6 1 0 0 1 1 1 0 Primosomal replication protein priC Thioredoxin_9 PF14595.6 KXH33390.1 - 0.03 14.1 0.5 0.099 12.4 0.0 2.0 2 0 0 2 2 2 0 Thioredoxin Redoxin PF08534.10 KXH33390.1 - 0.057 13.1 0.0 0.24 11.1 0.0 2.0 2 0 0 2 2 2 0 Redoxin Glutaredoxin PF00462.24 KXH33390.1 - 0.058 13.6 0.0 0.2 11.9 0.0 2.0 1 0 0 1 1 1 0 Glutaredoxin YabA PF06156.13 KXH33390.1 - 0.32 11.7 5.6 19 5.9 0.0 3.0 2 1 0 2 2 2 0 Initiation control protein YabA Spc7 PF08317.11 KXH33390.1 - 0.32 9.8 7.1 0.54 9.1 7.1 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein IF4E PF01652.18 KXH33391.1 - 4.3e-38 130.6 0.4 5.5e-38 130.3 0.4 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E EF-hand_9 PF14658.6 KXH33392.1 - 0.035 14.4 0.0 0.44 10.9 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain E3_binding PF02817.17 KXH33392.1 - 0.18 12.2 2.3 0.56 10.6 0.1 2.7 3 0 0 3 3 3 0 e3 binding domain HAGH_C PF16123.5 KXH33394.1 - 1.2e-23 83.4 1.8 1.9e-23 82.7 1.8 1.4 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 KXH33394.1 - 1.2e-17 64.6 0.4 1e-10 42.0 0.1 2.2 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KXH33394.1 - 0.00021 20.9 0.4 0.0024 17.4 0.4 2.2 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Peripla_BP_4 PF13407.6 KXH33394.1 - 0.027 14.0 0.2 0.17 11.4 0.0 2.0 2 0 0 2 2 2 0 Periplasmic binding protein domain LVIVD PF08309.11 KXH33394.1 - 0.12 11.8 0.3 0.21 10.9 0.3 1.4 1 0 0 1 1 1 0 LVIVD repeat Las1 PF04031.13 KXH33395.1 - 9.7e-64 214.1 1.3 1.4e-63 213.6 1.3 1.3 1 0 0 1 1 1 1 Las1-like Sacchrp_dh_C PF16653.5 KXH33396.1 - 5.2e-95 318.5 0.0 9.6e-95 317.7 0.0 1.4 2 0 0 2 2 2 1 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 KXH33396.1 - 2.8e-25 89.0 0.2 4.7e-25 88.3 0.2 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 KXH33396.1 - 6.7e-05 22.9 0.1 0.00022 21.2 0.0 1.9 2 0 0 2 2 2 1 NAD(P)H-binding Shikimate_DH PF01488.20 KXH33396.1 - 0.00012 22.2 0.0 0.00023 21.2 0.0 1.6 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase IlvN PF07991.12 KXH33396.1 - 0.012 15.2 0.2 0.087 12.4 0.0 2.4 2 1 1 3 3 3 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain GFO_IDH_MocA PF01408.22 KXH33396.1 - 0.12 13.2 0.2 0.49 11.2 0.1 2.0 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold SieB PF14163.6 KXH33396.1 - 0.18 11.3 0.0 3.2 7.2 0.0 2.2 2 0 0 2 2 2 0 Super-infection exclusion protein B Mid1 PF12929.7 KXH33397.1 - 0.3 10.2 1.3 0.43 9.7 1.3 1.2 1 0 0 1 1 1 0 Stretch-activated Ca2+-permeable channel component PfkB PF00294.24 KXH33400.1 - 0.0022 17.4 0.0 0.0028 17.0 0.0 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Sushi_2 PF09014.10 KXH33400.1 - 0.085 12.8 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Beta-2-glycoprotein-1 fifth domain WSC PF01822.19 KXH33401.1 - 1.7e-69 230.0 80.4 3.9e-18 65.4 12.0 5.2 5 0 0 5 5 5 4 WSC domain peroxidase PF00141.23 KXH33401.1 - 3.2e-22 79.4 0.1 6.6e-22 78.3 0.1 1.5 1 0 0 1 1 1 1 Peroxidase SPX PF03105.19 KXH33401.1 - 10 6.0 20.3 16 5.3 20.3 1.2 1 0 0 1 1 1 0 SPX domain MARVEL PF01284.23 KXH33403.1 - 0.001 19.1 17.6 0.029 14.4 18.0 2.1 1 1 0 1 1 1 1 Membrane-associating domain Creatininase PF02633.14 KXH33403.1 - 0.004 16.6 0.2 0.0056 16.2 0.2 1.2 1 0 0 1 1 1 1 Creatinine amidohydrolase DUF3422 PF11902.8 KXH33403.1 - 0.043 12.9 0.9 5.3 6.1 1.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3422) DUF3402 PF11882.8 KXH33404.1 - 1.3e-213 710.2 0.0 1.7e-213 709.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3402) N1221 PF07923.13 KXH33404.1 - 2e-89 299.6 0.2 3.3e-89 298.9 0.2 1.4 1 0 0 1 1 1 1 N1221-like protein NAD_kinase PF01513.21 KXH33405.1 - 1.1e-72 244.8 0.0 1.7e-72 244.1 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase BBP1_N PF15271.6 KXH33405.1 - 0.13 13.1 1.3 0.46 11.3 1.3 1.9 1 0 0 1 1 1 0 Spindle pole body component BBP1, Mps2-binding protein SpoOE-like PF09388.10 KXH33407.1 - 0.13 12.1 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 Spo0E like sporulation regulatory protein Abhydrolase_1 PF00561.20 KXH33408.1 - 1.8e-15 57.3 0.0 3.1e-12 46.7 0.0 3.1 2 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 KXH33408.1 - 1.8e-15 56.9 0.0 5.3e-15 55.4 0.0 1.8 2 0 0 2 2 2 1 TAP-like protein Hydrolase_4 PF12146.8 KXH33408.1 - 0.049 12.9 0.0 0.14 11.4 0.0 1.7 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Grg1 PF11034.8 KXH33410.1 - 7.8e-32 109.3 10.1 8.9e-32 109.1 10.1 1.0 1 0 0 1 1 1 1 Glucose-repressible protein Grg1 DUF3756 PF12581.8 KXH33410.1 - 0.077 12.9 0.2 0.13 12.2 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3756) EBP PF05241.12 KXH33411.1 - 2.4e-73 245.4 8.7 2.8e-73 245.2 8.7 1.0 1 0 0 1 1 1 1 Emopamil binding protein TMEM208_SND2 PF05620.11 KXH33411.1 - 0.48 10.2 10.8 0.28 11.0 2.4 2.3 2 0 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 Aldo_ket_red PF00248.21 KXH33412.1 - 1.3e-06 27.8 0.0 1.4e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Oxidored_molyb PF00174.19 KXH33414.1 - 1e-45 155.5 0.0 2.4e-45 154.2 0.0 1.6 2 0 0 2 2 2 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 KXH33414.1 - 7.5e-10 39.0 0.0 1.4e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain FAD_binding_4 PF01565.23 KXH33415.1 - 2.9e-16 59.5 0.1 4.6e-16 58.8 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KXH33415.1 - 0.0002 21.4 0.1 0.0004 20.4 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like Methyltransf_23 PF13489.6 KXH33417.1 - 2.3e-19 69.9 0.0 3.3e-19 69.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH33417.1 - 3e-09 37.5 0.0 8.3e-09 36.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH33417.1 - 5.1e-07 30.4 0.0 4.2e-06 27.4 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH33417.1 - 8.9e-07 28.8 0.0 7.5e-06 25.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH33417.1 - 3.2e-06 27.7 0.0 6.7e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXH33417.1 - 0.02 14.5 0.0 0.055 13.0 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase small domain Ubie_methyltran PF01209.18 KXH33417.1 - 0.039 13.3 0.0 6.2 6.1 0.0 2.7 2 1 1 3 3 3 0 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 KXH33417.1 - 0.098 12.1 0.3 2.2 7.7 0.0 2.3 2 0 0 2 2 2 0 Putative methyltransferase PrmA PF06325.13 KXH33417.1 - 0.14 11.5 0.2 0.32 10.3 0.0 1.6 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 KXH33418.1 - 2.3e-17 63.3 0.0 3.3e-17 62.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH33418.1 - 3.3e-08 34.1 0.0 7.3e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH33418.1 - 2.5e-07 30.6 0.0 2.1e-06 27.6 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH33418.1 - 3.8e-05 24.3 0.0 0.00031 21.4 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH33418.1 - 0.0019 18.8 0.0 0.0038 17.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KXH33418.1 - 0.01 15.3 0.0 0.023 14.2 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase MTS PF05175.14 KXH33418.1 - 0.063 12.8 0.0 0.097 12.2 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain FtsJ PF01728.19 KXH33418.1 - 0.2 11.8 0.0 0.29 11.2 0.0 1.4 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_16 PF10294.9 KXH33418.1 - 0.22 11.2 0.0 0.5 10.1 0.0 1.6 1 0 0 1 1 1 0 Lysine methyltransferase Aldedh PF00171.22 KXH33419.1 - 4.3e-163 543.1 0.6 4.8e-163 542.9 0.6 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KXH33419.1 - 0.0028 17.1 0.1 0.076 12.5 0.0 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF1487) BTB PF00651.31 KXH33420.1 - 0.019 15.2 0.0 0.041 14.1 0.0 1.5 1 0 0 1 1 1 0 BTB/POZ domain AAA PF00004.29 KXH33421.1 - 8.3e-19 68.3 0.0 1.4e-18 67.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KXH33421.1 - 9.3e-05 22.5 0.0 0.00023 21.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KXH33421.1 - 0.00015 22.0 0.1 0.0014 18.9 0.1 2.3 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 KXH33421.1 - 0.00052 20.4 0.1 0.0016 18.8 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain Zot PF05707.12 KXH33421.1 - 0.0015 18.2 0.1 0.021 14.5 0.0 2.4 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_18 PF13238.6 KXH33421.1 - 0.003 18.1 0.0 0.069 13.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.14 KXH33421.1 - 0.015 15.4 0.0 0.03 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 KXH33421.1 - 0.039 13.7 0.0 0.089 12.5 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_28 PF13521.6 KXH33421.1 - 0.08 13.2 0.0 0.18 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 KXH33421.1 - 0.082 12.0 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_11 PF13086.6 KXH33421.1 - 0.084 12.6 0.5 0.14 11.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 KXH33421.1 - 0.1 12.0 0.1 0.18 11.2 0.1 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 KXH33421.1 - 0.11 12.5 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 KXH33421.1 - 0.12 11.8 0.4 1.8 8.0 0.3 2.7 2 1 0 2 2 2 0 PhoH-like protein ATPase PF06745.13 KXH33421.1 - 0.18 11.1 0.1 0.43 9.9 0.1 1.5 1 0 0 1 1 1 0 KaiC MFS_1 PF07690.16 KXH33422.1 - 3.5e-33 115.0 34.4 4.5e-33 114.6 34.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily PTPLA PF04387.14 KXH33423.1 - 1e-49 168.5 9.0 1.5e-49 167.9 9.0 1.3 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA 2-oxoacid_dh PF00198.23 KXH33424.1 - 1.7e-72 243.7 0.0 2.5e-72 243.1 0.0 1.3 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KXH33424.1 - 5e-18 64.7 4.4 8.9e-18 63.9 4.4 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 KXH33424.1 - 9.8e-06 25.3 0.5 0.0002 21.1 0.1 2.5 1 1 1 2 2 2 1 Biotin-lipoyl like HlyD_3 PF13437.6 KXH33424.1 - 0.00087 20.0 0.9 0.33 11.7 0.1 2.6 1 1 1 2 2 2 1 HlyD family secretion protein GCV_H PF01597.19 KXH33424.1 - 0.0033 17.3 2.3 0.01 15.7 2.0 2.0 1 1 1 2 2 2 1 Glycine cleavage H-protein HlyD_D23 PF16576.5 KXH33424.1 - 0.0047 16.2 0.3 0.039 13.2 0.1 2.2 1 1 1 2 2 2 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion RnfC_N PF13375.6 KXH33424.1 - 0.0047 16.9 1.5 1.7 8.6 0.3 2.7 1 1 1 2 2 2 2 RnfC Barrel sandwich hybrid domain DUF2118 PF09891.9 KXH33424.1 - 0.041 13.8 0.8 0.26 11.2 0.2 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2118) TFIIA PF03153.13 KXH33424.1 - 0.13 12.2 11.3 0.17 11.8 11.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Peptidase_M23 PF01551.22 KXH33424.1 - 0.28 11.4 1.0 8.1 6.7 0.1 2.9 1 1 1 2 2 2 0 Peptidase family M23 Presenilin PF01080.17 KXH33424.1 - 0.39 9.4 3.7 0.6 8.8 3.7 1.2 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.12 KXH33424.1 - 0.8 9.5 8.9 1.4 8.7 8.9 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CCDC53 PF10152.9 KXH33424.1 - 0.97 9.8 11.6 0.12 12.8 7.0 1.9 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Trypan_PARP PF05887.11 KXH33424.1 - 2.2 8.2 20.8 4.2 7.3 20.8 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Transket_pyr PF02779.24 KXH33425.1 - 5e-59 199.0 0.0 7.4e-59 198.4 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 KXH33425.1 - 2.2e-54 184.4 0.0 4.1e-54 183.6 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 KXH33425.1 - 4.8e-52 175.7 0.0 7.9e-52 175.0 0.0 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal Amino_oxidase PF01593.24 KXH33426.1 - 6.2e-23 81.8 0.0 2.5e-15 56.7 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KXH33426.1 - 0.00027 21.1 0.0 0.00059 20.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain PG_isomerase_N PF18353.1 KXH33426.1 - 0.093 13.1 0.0 0.44 11.0 0.0 2.0 2 0 0 2 2 2 0 Phosphoglucose isomerase N-terminal domain DUF3328 PF11807.8 KXH33427.1 - 1.3e-29 103.5 6.3 2.7e-28 99.3 6.3 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) AA_permease_2 PF13520.6 KXH33429.1 - 1.9e-37 129.1 35.2 4.9e-31 108.0 20.6 2.0 1 1 1 2 2 2 2 Amino acid permease AA_permease PF00324.21 KXH33429.1 - 4.7e-13 48.5 32.3 2.9e-10 39.4 20.2 2.1 1 1 1 2 2 2 2 Amino acid permease DNA_pol_A_exo1 PF01612.20 KXH33430.1 - 0.0022 17.7 0.0 0.0034 17.1 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease Oxysterol_BP PF01237.18 KXH33431.1 - 2.1e-55 188.1 0.6 3.8e-48 164.2 0.0 2.0 1 1 1 2 2 2 2 Oxysterol-binding protein Peptidase_S10 PF00450.22 KXH33432.1 - 1.4e-81 275.1 0.9 2e-81 274.5 0.9 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase Lipase_GDSL PF00657.22 KXH33433.1 - 0.00015 21.8 0.1 0.0002 21.4 0.1 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase CFEM PF05730.11 KXH33434.1 - 0.0004 20.4 11.4 0.00068 19.7 11.4 1.4 1 1 0 1 1 1 1 CFEM domain VSG_B PF13206.6 KXH33434.1 - 0.68 9.1 6.8 0.8 8.9 6.8 1.1 1 0 0 1 1 1 0 Trypanosomal VSG domain MFS_1 PF07690.16 KXH33435.1 - 2.4e-22 79.4 28.5 2.4e-22 79.4 28.5 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KXH33435.1 - 1.8e-06 26.7 5.7 1.8e-06 26.7 5.7 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KXH33435.1 - 9.3e-06 24.8 23.9 0.00015 20.8 23.9 2.3 1 1 0 1 1 1 1 Sugar (and other) transporter Zn_clus PF00172.18 KXH33436.1 - 6.1e-06 26.3 12.8 1.1e-05 25.4 12.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KXH33436.1 - 2.4e-05 23.4 0.1 5.1e-05 22.2 0.1 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain SQS_PSY PF00494.19 KXH33436.1 - 0.029 13.9 0.1 0.066 12.7 0.1 1.5 1 0 0 1 1 1 0 Squalene/phytoene synthase RTA1 PF04479.13 KXH33437.1 - 8.7e-72 241.1 9.4 9.9e-72 240.9 9.4 1.0 1 0 0 1 1 1 1 RTA1 like protein Syndecan PF01034.20 KXH33437.1 - 0.019 14.9 0.2 0.019 14.9 0.2 2.1 2 0 0 2 2 2 0 Syndecan domain DUF485 PF04341.12 KXH33437.1 - 0.045 13.7 0.5 0.045 13.7 0.5 2.6 3 0 0 3 3 3 0 Protein of unknown function, DUF485 Serglycin PF04360.12 KXH33439.1 - 0.52 10.3 7.0 0.9 9.5 7.0 1.4 1 1 0 1 1 1 0 Serglycin SKG6 PF08693.10 KXH33440.1 - 0.00011 21.6 0.3 0.0002 20.7 0.3 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Mid2 PF04478.12 KXH33440.1 - 0.028 14.3 0.1 0.064 13.1 0.1 1.6 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Cyt-b5 PF00173.28 KXH33441.1 - 1.3e-12 47.7 0.0 1.6e-12 47.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Gram_pos_anchor PF00746.21 KXH33441.1 - 0.076 13.0 0.0 0.22 11.5 0.0 1.8 1 0 0 1 1 1 0 LPXTG cell wall anchor motif Scytalone_dh PF02982.14 KXH33442.1 - 1.3e-97 324.1 1.3 1.5e-97 323.9 1.3 1.0 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.6 KXH33442.1 - 9e-08 32.3 0.2 1.2e-07 31.9 0.2 1.2 1 0 0 1 1 1 1 SnoaL-like domain HET PF06985.11 KXH33443.1 - 1.1e-12 48.5 2.1 3.2e-09 37.3 0.1 2.7 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Glyco_hydro_62 PF03664.13 KXH33444.1 - 3e-158 525.3 17.1 3.5e-158 525.1 17.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 MIP PF00230.20 KXH33445.1 - 4.4e-46 157.4 7.8 5.3e-46 157.2 7.8 1.1 1 0 0 1 1 1 1 Major intrinsic protein Asp PF00026.23 KXH33446.1 - 1.7e-54 185.3 0.1 2.3e-54 184.9 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KXH33446.1 - 5.8e-10 39.7 2.7 1.3e-09 38.5 2.7 1.6 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KXH33446.1 - 0.0069 17.0 0.9 10 6.8 0.5 3.6 2 1 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 KXH33446.1 - 0.018 15.6 0.3 29 5.3 0.2 3.4 2 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease Kelch_5 PF13854.6 KXH33447.1 - 3.5e-14 52.4 1.3 1.9e-11 43.7 0.3 3.6 3 0 0 3 3 3 1 Kelch motif Kelch_4 PF13418.6 KXH33447.1 - 9.8e-06 25.5 15.4 0.00033 20.6 0.2 5.5 5 0 0 5 5 5 1 Galactose oxidase, central domain Gly-zipper_YMGG PF13441.6 KXH33447.1 - 0.0011 18.6 3.3 0.004 16.9 3.3 1.9 1 0 0 1 1 1 1 YMGG-like Gly-zipper Gly-zipper_Omp PF13488.6 KXH33447.1 - 0.0042 17.1 5.0 0.018 15.0 5.0 2.1 1 0 0 1 1 1 1 Glycine zipper CD99L2 PF12301.8 KXH33447.1 - 0.016 15.5 0.0 0.035 14.4 0.0 1.5 1 0 0 1 1 1 0 CD99 antigen like protein 2 DUF456 PF04306.13 KXH33447.1 - 0.045 14.1 0.3 0.087 13.1 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF456) Kelch_2 PF07646.15 KXH33447.1 - 0.07 13.1 3.4 1.4 9.1 0.1 3.8 3 0 0 3 3 3 0 Kelch motif Kelch_1 PF01344.25 KXH33447.1 - 0.35 10.5 10.1 4.7 6.9 0.1 4.6 4 0 0 4 4 4 0 Kelch motif Romo1 PF10247.9 KXH33447.1 - 0.41 11.0 2.5 0.47 10.9 0.1 2.2 2 0 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 Gly-zipper_OmpA PF13436.6 KXH33447.1 - 5 7.0 9.5 5.6 6.8 7.7 2.1 2 0 0 2 2 2 0 Glycine-zipper domain UDPGT PF00201.18 KXH33448.1 - 0.00018 20.4 0.0 0.00026 19.9 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 KXH33448.1 - 0.04 13.9 0.0 0.16 12.0 0.0 1.9 1 1 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_4 PF13692.6 KXH33448.1 - 0.076 13.4 0.0 1.4 9.3 0.0 2.7 3 0 0 3 3 3 0 Glycosyl transferases group 1 Ank_2 PF12796.7 KXH33449.1 - 1.1e-74 247.0 22.7 1.4e-11 44.8 0.1 8.1 1 1 9 10 10 10 10 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXH33449.1 - 1.7e-53 177.9 13.0 2.3e-09 37.3 0.0 8.7 5 2 3 9 9 9 9 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXH33449.1 - 9.6e-52 172.7 15.6 2.3e-09 37.6 0.4 10.2 4 4 5 10 10 10 9 Ankyrin repeats (many copies) Ank PF00023.30 KXH33449.1 - 8.9e-50 165.1 12.3 6e-05 23.3 0.0 12.1 12 0 0 12 12 12 10 Ankyrin repeat Ank_3 PF13606.6 KXH33449.1 - 1.6e-32 107.9 5.4 0.011 16.2 0.0 12.5 12 0 0 12 12 12 7 Ankyrin repeat SesA PF17107.5 KXH33449.1 - 1.6e-32 112.2 0.5 6.8e-32 110.2 0.5 2.2 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases NACHT PF05729.12 KXH33449.1 - 3.1e-09 37.0 0.0 5.9e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KXH33449.1 - 8.5e-05 23.0 0.0 0.00062 20.2 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KXH33449.1 - 0.00037 20.8 0.0 0.025 14.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KXH33449.1 - 0.028 14.8 0.0 0.091 13.2 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Glyco_hydro_61 PF03443.14 KXH33451.1 - 8.1e-61 205.5 0.1 1.1e-60 205.1 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.18 KXH33451.1 - 1.2e-05 25.1 6.1 1.2e-05 25.1 6.1 3.2 3 1 0 3 3 3 1 Fungal cellulose binding domain Cellulase PF00150.18 KXH33452.1 - 7.3e-22 78.1 4.7 1e-21 77.6 4.7 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.17 KXH33452.1 - 4.5e-08 32.6 0.0 9.4e-08 31.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_42 PF02449.15 KXH33452.1 - 0.00041 19.8 0.8 0.0013 18.2 0.0 2.0 3 0 0 3 3 3 1 Beta-galactosidase Hfq PF17209.3 KXH33452.1 - 0.16 11.7 0.1 0.45 10.2 0.0 1.7 2 0 0 2 2 2 0 Hfq protein Solute_trans_a PF03619.16 KXH33453.1 - 2.7e-63 214.0 18.4 3.2e-63 213.7 18.4 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DUF2628 PF10947.8 KXH33453.1 - 4.3 7.8 8.2 2.4 8.6 0.9 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2628) FA_hydroxylase PF04116.13 KXH33455.1 - 1.5e-23 83.6 21.0 1.5e-23 83.6 21.0 2.0 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily Fungal_trans_2 PF11951.8 KXH33456.1 - 1.5e-18 66.8 3.7 1e-17 64.1 3.7 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Acetyltransf_1 PF00583.25 KXH33456.1 - 1.8e-07 31.4 0.0 4.4e-07 30.1 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXH33456.1 - 1.4e-06 28.3 0.0 3e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXH33456.1 - 1.6e-06 28.4 0.0 3.9e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Zn_clus PF00172.18 KXH33456.1 - 0.00011 22.3 1.6 0.00021 21.4 1.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acetyltransf_CG PF14542.6 KXH33456.1 - 0.00056 20.0 0.0 0.0011 19.1 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 KXH33456.1 - 0.085 12.9 0.1 1.7 8.8 0.0 2.8 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXH33456.1 - 0.16 11.9 0.0 0.42 10.6 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein DAO PF01266.24 KXH33457.1 - 3.1e-32 112.5 0.8 4.1e-32 112.1 0.8 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXH33457.1 - 0.00043 20.5 0.7 0.00086 19.5 0.7 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KXH33457.1 - 0.0077 16.2 0.1 0.024 14.7 0.2 1.7 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KXH33457.1 - 0.0079 15.5 0.1 0.018 14.3 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXH33457.1 - 0.041 14.4 0.4 0.32 11.6 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AA_permease_2 PF13520.6 KXH33458.1 - 1e-41 143.2 45.8 1.3e-41 142.9 45.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXH33458.1 - 3e-12 45.9 38.5 4e-12 45.5 38.5 1.0 1 0 0 1 1 1 1 Amino acid permease ATP_synth_reg PF14960.6 KXH33458.1 - 3.4 7.2 4.9 0.43 10.1 0.3 1.9 2 0 0 2 2 2 0 ATP synthase regulation Cupin_1 PF00190.22 KXH33459.1 - 1.1e-36 125.8 0.0 9.9e-18 64.2 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 KXH33459.1 - 2.8e-20 71.8 0.1 9e-12 44.5 0.2 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 KXH33459.1 - 1.4e-07 31.1 0.2 0.00086 19.0 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) MannoseP_isomer PF01050.18 KXH33459.1 - 1.6e-05 24.9 0.0 0.0022 17.9 0.0 2.2 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase AraC_binding PF02311.19 KXH33459.1 - 0.00021 21.2 0.0 0.09 12.7 0.0 2.6 3 0 0 3 3 3 2 AraC-like ligand binding domain 3-HAO PF06052.12 KXH33459.1 - 0.0089 15.7 0.0 0.038 13.6 0.0 1.9 2 0 0 2 2 2 1 3-hydroxyanthranilic acid dioxygenase Cupin_6 PF12852.7 KXH33459.1 - 0.035 13.8 0.2 0.63 9.7 0.0 2.4 3 0 0 3 3 3 0 Cupin OATP PF03137.20 KXH33460.1 - 0.23 9.7 3.0 0.23 9.7 3.0 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family RRM_1 PF00076.22 KXH33461.1 - 3.6e-37 126.0 0.0 1.1e-17 63.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KXH33461.1 - 1.2e-05 25.4 0.0 0.15 12.2 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif DUF4140 PF13600.6 KXH33461.1 - 0.029 14.8 0.0 0.029 14.8 0.0 3.9 3 1 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) NDUFB10 PF10249.9 KXH33462.1 - 0.0014 19.2 0.0 0.0015 19.0 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 HWE_HK PF07536.14 KXH33462.1 - 0.11 13.2 0.0 0.17 12.6 0.0 1.2 1 0 0 1 1 1 0 HWE histidine kinase Ribosomal_L37 PF08561.10 KXH33463.1 - 1.4e-42 145.0 2.6 1.4e-42 145.0 2.6 1.6 2 0 0 2 2 2 1 Mitochondrial ribosomal protein L37 TAFII55_N PF04658.13 KXH33464.1 - 1.8e-47 161.1 0.0 4.6e-47 159.7 0.0 1.7 1 0 0 1 1 1 1 TAFII55 protein conserved region DUF4602 PF15375.6 KXH33464.1 - 1.2 9.4 10.9 0.06 13.7 2.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4602) DUF883 PF05957.13 KXH33464.1 - 5.9 7.6 10.2 0.4 11.3 4.2 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF3074 PF11274.8 KXH33465.1 - 8.8e-47 159.5 0.1 1.2e-46 159.0 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) DUF1840 PF08895.11 KXH33465.1 - 0.08 13.3 0.0 0.35 11.2 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) p450 PF00067.22 KXH33466.1 - 4.2e-74 250.0 0.0 5.4e-74 249.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Kinesin PF00225.23 KXH33470.1 - 4.4e-94 315.1 0.0 7.7e-94 314.3 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KXH33470.1 - 4e-21 75.5 0.0 1.4e-20 73.8 0.0 1.9 2 0 0 2 2 2 1 Microtubule binding PKcGMP_CC PF16808.5 KXH33470.1 - 0.01 15.7 1.0 0.01 15.7 1.0 4.0 4 0 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase ALC PF17527.2 KXH33470.1 - 0.016 14.9 0.3 0.037 13.7 0.3 1.6 1 0 0 1 1 1 0 Phage ALC protein LMP PF04778.12 KXH33470.1 - 0.2 11.6 5.3 0.51 10.2 0.7 3.3 3 2 0 3 3 3 0 LMP repeated region Tho2 PF11262.8 KXH33470.1 - 0.39 9.9 2.4 0.68 9.1 2.4 1.3 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 OmpH PF03938.14 KXH33470.1 - 0.78 10.1 7.9 11 6.3 4.9 2.5 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) CHD5 PF04420.14 KXH33470.1 - 7.7 6.4 5.1 17 5.2 5.1 1.5 1 0 0 1 1 1 0 CHD5-like protein GTP_EFTU PF00009.27 KXH33472.1 - 8.8e-59 198.3 0.0 1.3e-58 197.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 KXH33472.1 - 6.7e-16 58.1 0.0 1.7e-15 56.8 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 KXH33472.1 - 2.6e-07 30.6 0.0 5.5e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 KXH33472.1 - 6.8e-07 29.6 0.0 1.7e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_IV PF03764.18 KXH33472.1 - 5.4e-05 23.0 0.0 0.0014 18.4 0.0 3.0 3 0 0 3 3 3 1 Elongation factor G, domain IV MMR_HSR1 PF01926.23 KXH33472.1 - 0.036 14.2 0.0 0.1 12.7 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase Paf67 PF10255.9 KXH33473.1 - 6e-156 519.5 0.3 7.2e-156 519.2 0.3 1.1 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.17 KXH33473.1 - 0.02 15.0 0.0 0.11 12.7 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 KXH33473.1 - 0.068 13.0 0.0 0.35 10.8 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Usp PF00582.26 KXH33476.1 - 5.6e-16 59.3 0.4 1.6e-15 57.9 0.0 1.9 2 0 0 2 2 2 1 Universal stress protein family WRNPLPNID PF15017.6 KXH33476.1 - 0.33 11.9 0.2 0.33 11.9 0.2 3.3 3 1 0 3 3 3 0 Putative WW-binding domain and destruction box M20_dimer PF07687.14 KXH33478.1 - 4.2e-06 26.6 0.0 8.1e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 KXH33478.1 - 0.00043 20.1 0.0 0.0013 18.5 0.0 1.8 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 MFS_1 PF07690.16 KXH33480.1 - 1.7e-31 109.5 35.1 2.2e-31 109.1 35.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 KXH33480.1 - 5.9e-05 22.5 19.4 0.00038 19.9 9.0 2.2 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB DUF1270 PF06900.11 KXH33480.1 - 0.42 11.0 4.9 8.4 6.9 0.3 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1270) DUF4131 PF13567.6 KXH33480.1 - 2.4 7.8 8.2 0.073 12.7 0.8 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) Lipase_GDSL_2 PF13472.6 KXH33481.1 - 2.2e-19 70.6 0.0 3.1e-19 70.1 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KXH33481.1 - 2.2e-09 37.6 0.0 3e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase F-box-like PF12937.7 KXH33483.1 - 7.1e-06 25.8 0.0 1.9e-05 24.4 0.0 1.8 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 KXH33483.1 - 0.0096 15.8 1.3 0.18 11.7 0.3 2.4 2 0 0 2 2 2 1 F-box domain Sas10_Utp3 PF04000.15 KXH33546.1 - 5.7e-11 42.9 0.4 2e-10 41.1 0.0 2.1 2 0 0 2 2 2 1 Sas10/Utp3/C1D family Syntaxin_2 PF14523.6 KXH33546.1 - 0.17 12.3 1.1 0.5 10.8 0.1 2.0 2 0 0 2 2 2 0 Syntaxin-like protein adh_short PF00106.25 KXH33547.1 - 8e-33 113.5 0.0 1e-32 113.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXH33547.1 - 2.5e-24 86.1 0.0 3.3e-24 85.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH33547.1 - 4.5e-09 36.5 0.0 7.5e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.20 KXH33547.1 - 0.0011 19.1 0.0 0.0019 18.3 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase THF_DHG_CYH_C PF02882.19 KXH33547.1 - 0.0079 15.5 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_10 PF13460.6 KXH33547.1 - 0.011 15.6 0.1 0.035 14.0 0.1 1.9 1 1 0 1 1 1 0 NAD(P)H-binding ApbA PF02558.16 KXH33547.1 - 0.016 14.8 0.0 0.033 13.8 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA GDP_Man_Dehyd PF16363.5 KXH33547.1 - 0.054 12.9 0.0 0.076 12.4 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase F420_oxidored PF03807.17 KXH33547.1 - 0.069 13.7 0.0 0.62 10.7 0.1 2.1 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Glyoxalase PF00903.25 KXH33548.1 - 7.2e-09 35.9 5.8 8.4e-07 29.2 3.6 2.7 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily vATP-synt_AC39 PF01992.16 KXH33548.1 - 0.17 11.4 0.1 0.26 10.7 0.1 1.2 1 0 0 1 1 1 0 ATP synthase (C/AC39) subunit FAD_binding_3 PF01494.19 KXH33549.1 - 3.1e-81 273.3 0.0 4e-81 273.0 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KXH33549.1 - 0.0034 16.6 0.0 0.0094 15.2 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KXH33549.1 - 0.014 14.5 0.1 0.031 13.3 0.1 1.6 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_8 PF13450.6 KXH33549.1 - 0.028 14.7 0.4 0.098 12.9 0.4 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KXH33549.1 - 0.065 13.8 0.0 0.56 10.8 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KXH33549.1 - 0.1 11.6 0.3 0.18 10.9 0.3 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A p450 PF00067.22 KXH33550.1 - 2.8e-69 234.0 0.0 3.6e-69 233.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.18 KXH33551.1 - 3e-21 75.7 0.3 1e-20 73.9 0.1 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain FAA_hydrolase PF01557.18 KXH33552.1 - 2.6e-61 207.1 0.0 3.4e-61 206.7 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family adh_short_C2 PF13561.6 KXH33553.1 - 2.1e-56 191.1 0.1 3.2e-56 190.5 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXH33553.1 - 9.2e-49 165.6 0.1 1.4e-48 164.9 0.1 1.3 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXH33553.1 - 5.9e-11 42.6 0.1 1.1e-10 41.7 0.1 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KXH33553.1 - 2.3e-05 24.0 0.0 5.1e-05 22.8 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KXH33553.1 - 0.0048 16.0 0.0 0.0085 15.2 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 KXH33553.1 - 0.048 13.1 0.1 0.15 11.4 0.1 1.8 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase adh_short_C2 PF13561.6 KXH33554.1 - 1.6e-58 198.0 0.1 1.8e-58 197.9 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXH33554.1 - 5.9e-43 146.6 0.0 7.5e-43 146.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXH33554.1 - 2e-10 40.9 0.1 3e-10 40.3 0.1 1.1 1 0 0 1 1 1 1 KR domain Peripla_BP_4 PF13407.6 KXH33554.1 - 0.025 14.1 0.2 0.036 13.6 0.2 1.3 1 0 0 1 1 1 0 Periplasmic binding protein domain Tubulin PF00091.25 KXH33554.1 - 0.044 14.0 0.0 0.062 13.5 0.0 1.2 1 0 0 1 1 1 0 Tubulin/FtsZ family, GTPase domain Cupin_2 PF07883.11 KXH33555.1 - 4.3e-08 32.8 0.2 9.1e-08 31.7 0.2 1.5 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 KXH33555.1 - 1.2e-05 24.9 1.4 8.4e-05 22.2 0.1 2.4 2 1 1 3 3 3 1 Protein of unknown function (DUF861) Ectoine_synth PF06339.12 KXH33555.1 - 0.037 14.2 0.0 0.059 13.6 0.0 1.4 1 0 0 1 1 1 0 Ectoine synthase Mem_trans PF03547.18 KXH33558.1 - 0.64 8.3 1.3 0.95 7.8 1.3 1.2 1 0 0 1 1 1 0 Membrane transport protein PBP1_TM PF14812.6 KXH33558.1 - 6.2 7.3 10.3 12 6.3 10.3 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal SAPS PF04499.15 KXH33558.1 - 6.7 5.4 5.6 9.1 4.9 5.6 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF5423 PF17461.2 KXH33558.1 - 9 5.0 12.5 13 4.5 12.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5423) HIP1_clath_bdg PF16515.5 KXH33559.1 - 0.003 18.1 8.0 0.003 18.1 8.0 2.2 2 1 0 2 2 2 1 Clathrin-binding domain of Huntingtin-interacting protein 1 MscS_porin PF12795.7 KXH33559.1 - 0.7 9.4 17.5 0.021 14.4 6.9 2.6 3 0 0 3 3 3 0 Mechanosensitive ion channel porin domain DUF2205 PF10224.9 KXH33559.1 - 3.3 7.8 7.3 1.7 8.7 0.0 3.1 3 0 0 3 3 3 0 Short coiled-coil protein GAS PF13851.6 KXH33559.1 - 5.1 6.4 13.4 14 4.9 13.6 1.7 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 KXH33559.1 - 7.9 5.3 14.6 6.2 5.6 1.9 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein RRM_1 PF00076.22 KXH33560.1 - 1.8e-16 59.7 0.6 2.4e-16 59.3 0.0 1.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) L31 PF09784.9 KXH33561.1 - 1.2e-45 154.0 0.7 1.4e-45 153.9 0.7 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 MPTase-PolyVal PF18818.1 KXH33561.1 - 0.14 12.2 0.3 3.6 7.6 0.0 2.0 1 1 0 2 2 2 0 Metallopeptidase superfamily domain Sedlin_N PF04628.13 KXH33562.1 - 2.3e-46 157.1 0.0 2.7e-46 156.9 0.0 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 KXH33562.1 - 0.00036 20.5 0.1 0.022 14.7 0.0 2.2 1 1 1 2 2 2 2 Sybindin-like family CENP-T_C PF15511.6 KXH33563.1 - 8e-09 35.6 0.1 9.7e-09 35.3 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 KXH33563.1 - 3.5e-05 24.2 0.1 4.1e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 KXH33563.1 - 8.6e-05 22.6 0.1 0.00013 22.1 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 KXH33563.1 - 0.00036 20.7 0.1 0.00065 19.9 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 KXH33563.1 - 0.00042 20.7 0.1 0.00056 20.2 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 KXH33563.1 - 0.0087 16.1 0.0 0.01 15.9 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KXH33563.1 - 0.023 14.7 0.0 0.027 14.5 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 KXH33563.1 - 0.095 12.5 0.1 0.12 12.2 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) HIGH_NTase1_ass PF16581.5 KXH33563.1 - 0.11 12.5 0.0 0.12 12.4 0.0 1.1 1 0 0 1 1 1 0 Cytidyltransferase-related C-terminal region TPR_1 PF00515.28 KXH33564.1 - 8.9e-45 148.7 14.2 3.9e-07 29.6 0.1 10.5 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_2 PF07719.17 KXH33564.1 - 9.4e-37 122.2 23.3 4.5e-05 23.2 0.0 11.1 11 0 0 11 11 11 7 Tetratricopeptide repeat ANAPC3 PF12895.7 KXH33564.1 - 1.4e-30 105.3 18.4 1.1e-22 80.0 0.2 6.3 4 1 3 7 7 7 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 KXH33564.1 - 4.6e-30 101.3 17.4 0.006 16.7 0.0 10.9 11 1 0 11 11 10 7 Tetratricopeptide repeat TPR_17 PF13431.6 KXH33564.1 - 2.2e-21 74.6 9.3 0.0087 16.4 0.0 9.7 10 0 0 10 10 9 6 Tetratricopeptide repeat TPR_19 PF14559.6 KXH33564.1 - 3.5e-21 75.5 10.8 5.9e-05 23.5 0.5 8.0 7 1 0 8 8 8 4 Tetratricopeptide repeat TPR_7 PF13176.6 KXH33564.1 - 7.6e-21 72.6 6.9 0.041 13.9 0.0 8.8 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_11 PF13414.6 KXH33564.1 - 3.8e-20 71.3 6.3 7.4e-05 22.4 0.3 9.6 9 1 1 10 10 10 5 TPR repeat TPR_14 PF13428.6 KXH33564.1 - 3.9e-20 70.8 19.8 0.098 13.5 0.2 11.0 4 3 6 11 11 11 6 Tetratricopeptide repeat TPR_12 PF13424.6 KXH33564.1 - 9.7e-20 70.7 21.5 0.00039 20.6 0.1 8.7 4 2 4 8 8 8 7 Tetratricopeptide repeat TPR_16 PF13432.6 KXH33564.1 - 5.8e-18 65.3 18.3 7.8e-07 29.6 0.3 8.0 7 1 0 8 8 8 3 Tetratricopeptide repeat TPR_6 PF13174.6 KXH33564.1 - 6.5e-12 45.3 10.0 1.7 9.5 0.0 9.3 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_15 PF13429.6 KXH33564.1 - 2.3e-08 33.6 13.7 0.027 13.7 0.1 4.8 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_9 PF13371.6 KXH33564.1 - 1.1e-06 28.6 9.6 1.7 8.9 0.0 6.6 5 2 2 7 7 7 3 Tetratricopeptide repeat DUF2225 PF09986.9 KXH33564.1 - 3.1e-05 23.8 3.7 0.015 15.1 2.0 3.3 2 1 1 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2225) Fis1_TPR_C PF14853.6 KXH33564.1 - 0.031 14.3 3.9 22 5.2 0.0 6.0 6 0 0 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat TPR_4 PF07721.14 KXH33564.1 - 0.2 12.4 7.4 8.6 7.3 0.0 4.4 5 0 0 5 5 4 0 Tetratricopeptide repeat DUF5113 PF17140.4 KXH33564.1 - 0.65 9.8 3.1 0.46 10.3 0.6 2.2 2 0 0 2 2 1 0 Domain of unknown function (DUF5113) TMEM208_SND2 PF05620.11 KXH33565.1 - 7.2e-53 178.8 0.2 7.9e-53 178.7 0.2 1.0 1 0 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 DUF3605 PF12239.8 KXH33566.1 - 1.5e-58 197.5 0.0 1.8e-58 197.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) EBP PF05241.12 KXH33567.1 - 5e-58 195.5 9.4 6.3e-58 195.2 9.4 1.1 1 0 0 1 1 1 1 Emopamil binding protein BacA PF02673.18 KXH33567.1 - 0.038 13.7 0.8 0.5 10.0 0.1 2.1 2 0 0 2 2 2 0 Bacitracin resistance protein BacA Fungal_trans_2 PF11951.8 KXH33569.1 - 8.8e-15 54.4 0.9 1.3e-14 53.8 0.9 1.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain Stealth_CR3 PF17102.5 KXH33569.1 - 0.047 13.6 0.2 6.8 6.7 0.0 2.6 2 0 0 2 2 2 0 Stealth protein CR3, conserved region 3 p450 PF00067.22 KXH33570.1 - 1.6e-62 211.7 0.0 2.4e-62 211.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.18 KXH33570.1 - 1e-13 50.9 0.3 2e-13 50.0 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH33570.1 - 9.1e-06 25.7 10.4 2e-05 24.6 10.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_4 PF01565.23 KXH33571.1 - 2.4e-23 82.4 0.0 4.3e-23 81.6 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.19 KXH33571.1 - 3.9e-15 56.2 0.0 5.6e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain SKICH PF17751.1 KXH33571.1 - 0.06 13.9 0.0 0.1 13.1 0.0 1.4 1 0 0 1 1 1 0 SKICH domain PrpF PF04303.13 KXH33572.1 - 1.8e-88 297.1 0.0 2.3e-88 296.7 0.0 1.1 1 0 0 1 1 1 1 PrpF protein PBP PF01161.20 KXH33573.1 - 5.6e-18 65.5 0.0 8.1e-18 65.0 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein AAA_18 PF13238.6 KXH33574.1 - 9.4e-09 35.9 0.0 1.8e-08 35.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KXH33574.1 - 5e-05 23.5 0.0 0.0001 22.5 0.0 1.5 2 0 0 2 2 2 1 AAA domain APS_kinase PF01583.20 KXH33574.1 - 0.0049 16.8 0.0 0.0082 16.0 0.0 1.4 1 1 0 1 1 1 1 Adenylylsulphate kinase AAA_5 PF07728.14 KXH33574.1 - 0.014 15.4 0.0 0.93 9.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Ploopntkinase3 PF18751.1 KXH33574.1 - 0.054 13.4 0.0 0.1 12.5 0.0 1.5 1 1 0 1 1 1 0 P-loop Nucleotide Kinase3 AAA_16 PF13191.6 KXH33574.1 - 0.098 13.0 0.0 0.21 11.9 0.0 1.5 1 1 1 2 2 2 0 AAA ATPase domain Fungal_trans PF04082.18 KXH33575.1 - 0.015 14.3 0.3 0.028 13.4 0.3 1.4 1 0 0 1 1 1 0 Fungal specific transcription factor domain T2SSF PF00482.23 KXH33575.1 - 0.041 13.8 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F 2OG-FeII_Oxy_3 PF13640.6 KXH33576.1 - 3.1e-07 31.2 0.1 2.6e-06 28.2 0.3 2.3 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily PIG-X PF08320.12 KXH33577.1 - 5e-71 239.0 0.0 7.3e-71 238.4 0.0 1.3 1 0 0 1 1 1 1 PIG-X / PBN1 Rhodanese PF00581.20 KXH33578.1 - 1.2e-07 32.3 0.0 2.9e-07 31.0 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain Homeodomain PF00046.29 KXH33578.1 - 0.00016 21.4 0.9 0.00038 20.3 0.3 1.9 2 0 0 2 2 2 1 Homeodomain Mre11_DNA_bind PF04152.14 KXH33579.1 - 0.18 12.1 0.0 0.27 11.5 0.0 1.2 1 0 0 1 1 1 0 Mre11 DNA-binding presumed domain DNA_primase_S PF01896.19 KXH33620.1 - 4.5e-65 219.0 0.1 6.1e-65 218.6 0.1 1.2 1 0 0 1 1 1 1 DNA primase small subunit tRNA_m1G_MT PF01746.21 KXH33621.1 - 1.7e-29 102.9 0.0 4.2e-21 75.5 0.0 2.2 2 0 0 2 2 2 2 tRNA (Guanine-1)-methyltransferase ANAPC16 PF17256.2 KXH33621.1 - 0.036 14.4 0.4 0.079 13.3 0.4 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex, subunit 16 MutS_V PF00488.21 KXH33622.1 - 1.4e-83 279.6 0.1 2.2e-83 278.9 0.1 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KXH33622.1 - 3e-38 132.0 2.3 4.4e-38 131.4 0.6 2.2 3 0 0 3 3 3 1 MutS domain III MutS_II PF05188.17 KXH33622.1 - 1.8e-23 83.3 0.5 5.9e-22 78.4 0.1 2.9 2 0 0 2 2 2 1 MutS domain II MutS_I PF01624.20 KXH33622.1 - 6.3e-21 74.7 0.0 3.8e-20 72.2 0.0 2.2 2 0 0 2 2 2 1 MutS domain I MutS_IV PF05190.18 KXH33622.1 - 2.2e-18 66.4 2.6 6.6e-18 64.9 1.3 2.5 2 0 0 2 2 2 1 MutS family domain IV Tim17 PF02466.19 KXH33623.1 - 5.8e-07 29.9 9.8 1.3e-06 28.8 8.8 1.9 1 1 1 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family Cytochrom_B558a PF05038.13 KXH33623.1 - 0.17 11.4 0.9 0.4 10.2 0.2 2.0 1 1 1 2 2 2 0 Cytochrome Cytochrome b558 alpha-subunit ABA_WDS PF02496.16 KXH33623.1 - 1.1 9.8 4.2 4.7 7.7 0.6 2.8 3 0 0 3 3 3 0 ABA/WDS induced protein DUF543 PF04418.12 KXH33623.1 - 6.1 6.9 6.2 1.3 9.1 1.7 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF543) UCH PF00443.29 KXH33625.1 - 7.4e-40 137.1 0.0 1.3e-39 136.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.6 KXH33625.1 - 6.9e-26 90.0 3.5 8.1e-12 44.9 0.1 3.4 3 0 0 3 3 3 2 A repeated domain in UCH-protein UCH_1 PF13423.6 KXH33625.1 - 2.3e-06 27.4 1.1 0.019 14.5 0.2 2.4 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUF3572 PF12096.8 KXH33625.1 - 0.18 12.0 0.4 7.6 6.8 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3572) XFP_N PF09364.10 KXH33627.1 - 9.3e-164 544.5 0.0 1.2e-163 544.1 0.0 1.1 1 0 0 1 1 1 1 XFP N-terminal domain XFP PF03894.15 KXH33627.1 - 2.8e-82 274.7 0.0 4.5e-82 274.0 0.0 1.3 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase XFP_C PF09363.10 KXH33627.1 - 1.2e-80 269.7 0.0 1.8e-80 269.2 0.0 1.2 1 0 0 1 1 1 1 XFP C-terminal domain Ras PF00071.22 KXH33628.1 - 4e-39 133.8 0.0 2.2e-25 89.1 0.0 2.1 2 0 0 2 2 2 2 Ras family Roc PF08477.13 KXH33628.1 - 3e-12 46.8 0.2 1.1e-11 45.0 0.0 2.0 3 0 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXH33628.1 - 0.00029 20.4 0.0 0.001 18.5 0.0 1.8 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KXH33628.1 - 0.0013 18.8 0.0 0.0023 18.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KXH33628.1 - 0.05 13.1 0.1 0.58 9.7 0.0 2.5 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain PRK PF00485.18 KXH33628.1 - 0.1 12.3 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Peptidase_C58 PF03543.14 KXH33629.1 - 0.0001 22.1 0.8 0.038 13.7 0.1 2.4 1 1 0 2 2 2 2 Yersinia/Haemophilus virulence surface antigen ADP_ribosyl_GH PF03747.14 KXH33629.1 - 0.14 11.9 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 ADP-ribosylglycohydrolase ApoLp-III PF07464.11 KXH33630.1 - 0.0023 18.0 0.1 0.0028 17.8 0.1 1.2 1 0 0 1 1 1 1 Apolipophorin-III precursor (apoLp-III) MCPsignal PF00015.21 KXH33630.1 - 0.039 13.8 0.8 0.064 13.1 0.8 1.5 1 1 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain ABC_tran_CTD PF16326.5 KXH33630.1 - 0.092 13.0 0.3 0.14 12.4 0.3 1.3 1 0 0 1 1 1 0 ABC transporter C-terminal domain Cytochrom_B562 PF07361.11 KXH33630.1 - 0.11 13.2 0.1 0.15 12.7 0.1 1.2 1 0 0 1 1 1 0 Cytochrome b562 DUF4795 PF16043.5 KXH33630.1 - 0.11 12.1 0.1 0.15 11.7 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) Pyridoxal_deC PF00282.19 KXH33631.1 - 2.7e-76 256.7 0.0 3.2e-76 256.5 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 KXH33631.1 - 1.5e-06 27.7 0.0 2e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 KXH33631.1 - 5.4e-05 22.3 0.0 9.1e-05 21.6 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Neuralized PF07177.12 KXH33631.1 - 0.14 12.2 0.0 1 9.4 0.0 2.3 3 0 0 3 3 3 0 Neuralized PUF PF00806.19 KXH33632.1 - 2.6e-12 45.7 0.0 0.08 12.7 0.0 6.2 6 0 0 6 6 6 4 Pumilio-family RNA binding repeat Glyco_hydro_28 PF00295.17 KXH33633.1 - 1e-45 156.2 10.7 2e-44 152.0 6.7 2.1 2 0 0 2 2 2 2 Glycosyl hydrolases family 28 p450 PF00067.22 KXH33634.1 - 3.6e-60 204.0 0.0 5.2e-60 203.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 DUF167 PF02594.16 KXH33635.1 - 2.1e-21 75.8 0.3 4.2e-21 74.8 0.3 1.5 1 0 0 1 1 1 1 Uncharacterised ACR, YggU family COG1872 2OG-FeII_Oxy PF03171.20 KXH33635.1 - 2.4e-19 69.7 0.0 6.1e-19 68.4 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 KXH33635.1 - 7.2e-16 59.0 0.0 1.5e-15 58.0 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Glyco_hydro_18 PF00704.28 KXH33636.1 - 3.9e-73 246.9 0.2 4.7e-73 246.6 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 KXH33636.1 - 1.7e-08 34.8 21.1 1.7e-08 34.8 21.1 2.5 3 0 0 3 3 3 1 Chitin recognition protein DUF4015 PF13200.6 KXH33636.1 - 0.0023 17.1 0.0 0.0032 16.6 0.0 1.1 1 0 0 1 1 1 1 Putative glycosyl hydrolase domain RST PF12174.8 KXH33636.1 - 0.11 12.5 0.2 0.25 11.3 0.1 1.6 2 0 0 2 2 2 0 RCD1-SRO-TAF4 (RST) plant domain Ank_3 PF13606.6 KXH33637.1 - 9.6e-08 31.7 0.0 0.0028 18.0 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 KXH33637.1 - 4.4e-06 26.9 0.0 0.038 14.4 0.0 3.7 3 1 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 KXH33637.1 - 1.7e-05 25.3 0.0 0.032 14.8 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXH33637.1 - 0.0007 20.1 0.0 1.3 9.7 0.0 4.0 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXH33637.1 - 0.0028 18.0 0.0 0.039 14.3 0.0 2.5 3 0 0 3 3 3 1 Ankyrin repeats (many copies) EB PF01683.18 KXH33638.1 - 0.0041 17.4 3.2 0.011 16.0 3.2 1.7 1 0 0 1 1 1 1 EB module MFS_1 PF07690.16 KXH33639.1 - 3.9e-36 124.7 35.4 2.5e-35 122.0 34.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH33639.1 - 3.3e-11 42.7 7.5 3.3e-11 42.7 7.5 2.1 2 1 0 2 2 2 1 Sugar (and other) transporter Sm_multidrug_ex PF06695.11 KXH33639.1 - 0.0011 19.6 3.4 1.4 9.6 3.1 2.9 2 0 0 2 2 2 2 Putative small multi-drug export protein HET PF06985.11 KXH33640.1 - 0.022 15.1 0.2 0.051 13.9 0.2 1.5 1 0 0 1 1 1 0 Heterokaryon incompatibility protein (HET) DUF4870 PF09685.10 KXH33640.1 - 0.51 10.5 0.0 0.51 10.5 0.0 4.0 4 1 0 4 4 4 0 Domain of unknown function (DUF4870) FAD_binding_4 PF01565.23 KXH33641.1 - 8.2e-09 35.3 0.0 9e-08 31.9 0.0 2.2 1 1 0 1 1 1 1 FAD binding domain ALO PF04030.14 KXH33641.1 - 1.5e-06 28.2 1.1 0.007 16.2 0.1 2.2 2 0 0 2 2 2 2 D-arabinono-1,4-lactone oxidase Chol_subst-bind PF09129.11 KXH33641.1 - 2 7.3 6.8 18 4.2 6.7 2.5 1 1 0 1 1 1 0 Cholesterol oxidase, substrate-binding Mur_ligase PF01225.25 KXH33645.1 - 0.17 12.3 0.0 0.29 11.5 0.0 1.3 1 0 0 1 1 1 0 Mur ligase family, catalytic domain F-box-like PF12937.7 KXH33646.1 - 0.0033 17.3 0.0 0.025 14.5 0.0 2.3 1 1 0 1 1 1 1 F-box-like FUSC-like PF12805.7 KXH33646.1 - 0.034 13.2 0.0 0.047 12.8 0.0 1.1 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS Polysacc_deac_1 PF01522.21 KXH33662.1 - 1.1e-14 54.4 0.0 2.1e-14 53.5 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase 2_5_RNA_ligase2 PF13563.6 KXH33665.1 - 4.4e-30 104.6 0.1 8.1e-30 103.7 0.1 1.5 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily PAP_central PF04928.17 KXH33665.1 - 3.3e-21 75.4 0.0 6.3e-21 74.5 0.0 1.4 1 0 0 1 1 1 1 Poly(A) polymerase central domain MJ1316 PF04457.12 KXH33665.1 - 1.5e-18 67.3 0.4 3.5e-18 66.1 0.4 1.7 1 0 0 1 1 1 1 MJ1316 RNA cyclic group end recognition domain Exo_endo_phos PF03372.23 KXH33665.1 - 9e-07 28.6 0.0 1.8e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family NTP_transf_2 PF01909.23 KXH33665.1 - 0.00019 21.6 0.0 0.00046 20.4 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain YL1 PF05764.13 KXH33665.1 - 0.0019 18.4 3.1 0.003 17.7 3.1 1.2 1 0 0 1 1 1 1 YL1 nuclear protein Cwf_Cwc_15 PF04889.12 KXH33665.1 - 0.62 9.7 7.1 1.2 8.8 7.1 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Exo70 PF03081.15 KXH33666.1 - 3e-89 299.7 0.0 7e-89 298.5 0.0 1.6 1 0 0 1 1 1 1 Exo70 exocyst complex subunit RHD3 PF05879.12 KXH33666.1 - 0.045 11.9 0.3 0.088 10.9 0.3 1.4 1 0 0 1 1 1 0 Root hair defective 3 GTP-binding protein (RHD3) Baculo_PEP_C PF04513.12 KXH33666.1 - 0.16 12.0 6.2 22 5.1 1.0 4.0 4 1 1 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2203 PF09969.9 KXH33666.1 - 0.95 10.2 5.4 0.39 11.4 0.2 2.9 4 0 0 4 4 4 0 Uncharacterized conserved protein (DUF2203) GAS PF13851.6 KXH33666.1 - 1.4 8.2 11.1 2.9 7.2 0.2 3.6 4 0 0 4 4 4 0 Growth-arrest specific micro-tubule binding Aminotran_3 PF00202.21 KXH33667.1 - 5.3e-83 278.9 0.0 6.4e-83 278.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III MCM PF00493.23 KXH33668.1 - 3.8e-97 323.8 0.3 6.7e-97 323.0 0.3 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KXH33668.1 - 2.1e-31 108.4 0.0 3.8e-31 107.5 0.0 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KXH33668.1 - 1.7e-23 82.9 0.7 3.6e-23 81.8 0.7 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KXH33668.1 - 3.6e-11 43.6 0.0 1.3e-10 41.8 0.0 1.9 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KXH33668.1 - 3.5e-07 29.8 0.0 4.1e-06 26.3 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KXH33668.1 - 0.0032 17.3 0.0 0.0088 15.9 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KXH33668.1 - 0.019 14.7 0.0 0.046 13.4 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF4919 PF16266.5 KXH33668.1 - 0.081 12.9 0.0 0.42 10.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4919) PfkB PF00294.24 KXH33669.1 - 4.1e-16 59.2 0.1 7.3e-09 35.3 0.8 2.1 2 0 0 2 2 2 2 pfkB family carbohydrate kinase FA_desaturase PF00487.24 KXH33670.1 - 5.1e-25 88.8 18.3 1e-24 87.8 18.3 1.4 1 1 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 KXH33670.1 - 7.3e-08 32.7 0.0 1.3e-06 28.6 0.0 2.3 2 1 0 2 2 2 1 Domain of unknown function (DUF3474) BES1_N PF05687.13 KXH33670.1 - 2 8.8 3.6 3.9 7.9 3.6 1.4 1 0 0 1 1 1 0 BES1/BZR1 plant transcription factor, N-terminal Peptidase_M35 PF02102.15 KXH33672.1 - 1.3e-70 238.1 13.4 1.5e-70 237.9 13.4 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.6 KXH33672.1 - 1e-38 133.2 3.2 1e-38 133.2 3.2 1.5 1 1 0 1 1 1 1 Lysine-specific metallo-endopeptidase Calycin_like PF13944.6 KXH33672.1 - 0.01 16.1 3.5 0.052 13.8 1.6 2.6 1 1 1 2 2 2 0 Calycin-like beta-barrel domain Chitin_bind_1 PF00187.19 KXH33677.1 - 0.054 14.0 23.2 1.6 9.2 17.2 3.1 3 0 0 3 3 3 0 Chitin recognition protein LysM PF01476.20 KXH33678.1 - 1.1e-11 44.6 0.0 1.8e-05 24.7 0.0 5.8 7 0 0 7 7 7 2 LysM domain CxC6 PF18721.1 KXH33678.1 - 0.73 10.2 3.9 0.74 10.1 0.1 3.0 3 0 0 3 3 3 0 CxC6 like cysteine cluster associated with KDZ transposases Peptidase_M20 PF01546.28 KXH33680.1 - 3.3e-29 102.1 0.0 4.4e-29 101.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KXH33680.1 - 0.06 13.3 0.0 0.14 12.1 0.0 1.6 1 1 0 1 1 1 0 Peptidase dimerisation domain MFS_1 PF07690.16 KXH33681.1 - 3.8e-38 131.3 27.9 3.8e-38 131.3 27.9 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans PF04082.18 KXH33682.1 - 1.5e-15 56.9 0.2 2.6e-15 56.2 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain bZIP_1 PF00170.21 KXH33684.1 - 1.4e-05 25.1 6.8 2.4e-05 24.3 6.8 1.4 1 0 0 1 1 1 1 bZIP transcription factor Tox-GHH2 PF15635.6 KXH33684.1 - 0.0083 16.6 0.1 0.016 15.7 0.1 1.4 1 0 0 1 1 1 1 GHH signature containing HNH/Endo VII superfamily nuclease toxin 2 PH_2 PF08458.10 KXH33684.1 - 0.04 14.3 0.2 0.28 11.5 0.0 2.2 2 1 0 2 2 2 0 Plant pleckstrin homology-like region REC114-like PF15165.6 KXH33684.1 - 0.06 13.1 0.0 0.092 12.5 0.0 1.3 1 0 0 1 1 1 0 Meiotic recombination protein REC114-like DUF4570 PF15134.6 KXH33684.1 - 0.32 11.0 5.9 3.3 7.8 2.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4570) Lactonase PF10282.9 KXH33685.1 - 0.00011 21.7 0.0 0.00045 19.6 0.0 2.0 2 1 0 2 2 2 1 Lactonase, 7-bladed beta-propeller DUF1815 PF08844.10 KXH33685.1 - 0.026 14.5 0.1 0.071 13.1 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1815) Aa_trans PF01490.18 KXH33686.1 - 9e-29 100.4 35.0 1e-28 100.2 35.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein SLATT_1 PF18181.1 KXH33686.1 - 1.1 9.2 9.8 7.1 6.6 2.8 3.1 3 0 0 3 3 3 0 SMODS and SLOG-associating 2TM effector domain 1 Polysacc_deac_1 PF01522.21 KXH33687.1 - 1.1e-18 67.3 0.0 2.3e-18 66.3 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 KXH33687.1 - 1.5e-05 24.8 0.0 2.6e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) DUF2194 PF09960.9 KXH33687.1 - 0.14 10.5 0.0 0.17 10.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2194) ADH_N PF08240.12 KXH33688.1 - 1.1e-21 76.8 0.4 3.2e-21 75.3 0.4 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXH33688.1 - 4.9e-17 62.1 0.1 1.2e-16 60.8 0.1 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KXH33688.1 - 0.0026 17.2 0.0 0.0042 16.5 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain XdhC_C PF13478.6 KXH33688.1 - 0.066 13.7 0.3 0.21 12.1 0.0 2.0 3 0 0 3 3 3 0 XdhC Rossmann domain ThiF PF00899.21 KXH33688.1 - 0.098 12.0 0.7 0.59 9.4 0.6 2.0 2 0 0 2 2 2 0 ThiF family Amidase PF01425.21 KXH33689.1 - 3e-87 293.5 0.1 3.8e-87 293.1 0.1 1.1 1 0 0 1 1 1 1 Amidase MSP1b PF03429.13 KXH33689.1 - 0.017 13.3 0.0 0.026 12.7 0.0 1.2 1 0 0 1 1 1 0 Major surface protein 1B Zn_clus PF00172.18 KXH33690.1 - 7.1e-07 29.3 10.0 1.2e-06 28.5 10.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KXH33690.1 - 0.0003 19.7 0.2 0.00047 19.1 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short_C2 PF13561.6 KXH33691.1 - 1.6e-57 194.8 0.4 2e-57 194.5 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXH33691.1 - 8.9e-42 142.8 0.2 1.2e-41 142.4 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXH33691.1 - 3.6e-07 30.3 0.1 7.1e-07 29.3 0.1 1.5 1 1 0 1 1 1 1 KR domain ThiF PF00899.21 KXH33691.1 - 0.00084 18.8 1.4 0.022 14.1 0.7 2.7 2 1 1 3 3 3 1 ThiF family DUF5448 PF17526.2 KXH33691.1 - 0.016 15.4 0.0 0.21 11.8 0.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5448) Polysacc_synt_2 PF02719.15 KXH33691.1 - 0.16 11.1 0.0 0.24 10.5 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Fungal_trans PF04082.18 KXH33692.1 - 9e-15 54.4 0.0 2.4e-14 53.0 0.1 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KXH33692.1 - 3.5e-08 33.5 11.0 2.8e-05 24.3 5.1 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXH33692.1 - 3.5e-05 24.3 7.3 0.00079 20.1 3.7 3.0 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2HC_2 PF13913.6 KXH33692.1 - 0.0055 16.6 2.4 0.013 15.3 2.4 1.6 1 0 0 1 1 1 1 zinc-finger of a C2HC-type zf-H2C2_2 PF13465.6 KXH33692.1 - 0.0076 16.6 9.7 0.013 15.9 1.0 2.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KXH33692.1 - 0.058 13.7 0.3 0.15 12.4 0.3 1.7 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-UBR PF02207.20 KXH33692.1 - 0.072 13.3 0.9 0.18 12.0 0.9 1.6 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) zf-Di19 PF05605.12 KXH33692.1 - 0.21 11.9 1.2 0.4 11.0 1.2 1.4 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.6 KXH33692.1 - 2.2 8.1 4.0 5.5 6.8 4.0 1.7 1 0 0 1 1 1 0 C2H2-type zinc-finger domain Sulfotransfer_4 PF17784.1 KXH33693.1 - 2.8e-61 207.1 0.0 3.3e-61 206.8 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KXH33693.1 - 3.5e-05 24.3 0.2 0.051 13.9 0.0 2.5 2 1 1 3 3 3 2 Sulfotransferase family Cofilin_ADF PF00241.20 KXH33694.1 - 9.8e-39 131.9 0.0 6.8e-23 80.8 0.0 2.1 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein Mito_carr PF00153.27 KXH33695.1 - 1.4e-67 223.6 2.6 2e-21 75.7 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein WD40 PF00400.32 KXH33696.1 - 2.9e-45 151.3 14.6 1e-06 29.3 0.4 8.8 8 0 0 8 8 8 7 WD domain, G-beta repeat Nup160 PF11715.8 KXH33696.1 - 3e-13 49.3 0.1 0.02 13.6 0.0 4.2 3 1 1 4 4 4 4 Nucleoporin Nup120/160 F-box-like PF12937.7 KXH33696.1 - 5.5e-13 48.6 0.1 1e-12 47.7 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXH33696.1 - 1.3e-09 37.7 0.0 3e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 F-box domain ANAPC4_WD40 PF12894.7 KXH33696.1 - 5e-09 36.3 0.2 0.086 13.2 0.0 6.0 2 2 5 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain F-box_4 PF15966.5 KXH33696.1 - 6.7e-05 22.7 0.0 0.0002 21.2 0.0 1.8 1 0 0 1 1 1 1 F-box WD40_like PF17005.5 KXH33696.1 - 0.00073 18.9 0.1 0.54 9.5 0.0 2.6 2 1 0 3 3 3 2 WD40-like domain BBS2_Mid PF14783.6 KXH33696.1 - 0.0028 17.7 0.0 1.1 9.3 0.0 3.9 3 1 1 4 4 4 1 Ciliary BBSome complex subunit 2, middle region BRK PF07533.16 KXH33696.1 - 0.046 13.3 0.1 30 4.3 0.0 3.8 4 0 0 4 4 4 0 BRK domain PALB2_WD40 PF16756.5 KXH33696.1 - 1 8.2 3.0 20 4.0 0.1 3.3 2 2 1 3 3 3 0 Partner and localizer of BRCA2 WD40 domain BUD22 PF09073.10 KXH33697.1 - 6.5 6.0 8.5 0.69 9.2 3.0 1.9 2 0 0 2 2 2 0 BUD22 SRR1 PF07985.12 KXH33703.1 - 7.3e-12 45.1 0.0 1.2e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 SRR1 Med13_N PF11597.8 KXH33703.1 - 0.047 13.1 0.0 0.066 12.6 0.0 1.2 1 0 0 1 1 1 0 Mediator complex subunit 13 N-terminal Ribosomal_L32p PF01783.23 KXH33703.1 - 0.1 12.9 1.3 4.8 7.5 0.1 2.7 2 0 0 2 2 2 0 Ribosomal L32p protein family PUL PF08324.11 KXH33705.1 - 2.3e-66 223.9 0.7 3.4e-66 223.3 0.7 1.3 1 0 0 1 1 1 1 PUL domain PFU PF09070.11 KXH33705.1 - 7.7e-45 151.8 0.2 1.3e-44 151.0 0.2 1.4 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.32 KXH33705.1 - 4.5e-34 115.9 3.5 2.9e-06 27.9 0.0 7.7 7 0 0 7 7 7 6 WD domain, G-beta repeat WD40_like PF17005.5 KXH33705.1 - 0.0035 16.7 0.0 0.015 14.6 0.0 2.0 2 0 0 2 2 2 1 WD40-like domain WD40 PF00400.32 KXH33706.1 - 8.5e-23 80.2 3.7 8.4e-08 32.8 0.0 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXH33706.1 - 0.00058 20.1 0.1 2.7 8.4 0.0 3.6 2 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KXH33706.1 - 0.0045 16.0 0.0 0.65 8.9 0.0 2.2 2 0 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Abhydrolase_3 PF07859.13 KXH33707.1 - 3.2e-19 69.6 0.1 4.6e-19 69.1 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KXH33707.1 - 9e-05 22.0 0.0 0.00043 19.8 0.0 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family Chlorophyllase2 PF12740.7 KXH33707.1 - 0.00015 20.8 0.0 0.00022 20.2 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme COesterase PF00135.28 KXH33707.1 - 0.0028 16.6 0.0 0.0041 16.1 0.0 1.3 1 1 0 1 1 1 1 Carboxylesterase family Esterase PF00756.20 KXH33707.1 - 0.0038 16.9 0.0 0.0059 16.3 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Chlorophyllase PF07224.11 KXH33707.1 - 0.0042 16.1 0.0 0.0057 15.7 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase AXE1 PF05448.12 KXH33707.1 - 0.0052 15.5 0.1 0.023 13.4 0.0 1.8 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) Peptidase_S15 PF02129.18 KXH33707.1 - 0.038 13.6 0.0 0.07 12.7 0.0 1.5 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) VSP PF03302.13 KXH33708.1 - 0.00061 18.7 2.1 0.00081 18.3 2.1 1.1 1 0 0 1 1 1 1 Giardia variant-specific surface protein Rax2 PF12768.7 KXH33708.1 - 0.0022 17.5 0.2 0.0032 16.9 0.2 1.2 1 0 0 1 1 1 1 Cortical protein marker for cell polarity Syndecan PF01034.20 KXH33708.1 - 0.013 15.4 0.1 0.024 14.5 0.1 1.4 1 0 0 1 1 1 0 Syndecan domain Podoplanin PF05808.11 KXH33708.1 - 0.015 15.4 2.9 0.027 14.6 2.9 1.3 1 0 0 1 1 1 0 Podoplanin FeoB_associated PF12669.7 KXH33708.1 - 0.019 15.3 0.2 0.035 14.5 0.2 1.4 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein Glycophorin_A PF01102.18 KXH33708.1 - 0.055 13.7 0.1 0.092 13.0 0.1 1.3 1 0 0 1 1 1 0 Glycophorin A NRIP1_repr_1 PF15687.5 KXH33708.1 - 0.1 12.3 1.8 0.16 11.7 1.8 1.2 1 0 0 1 1 1 0 Nuclear receptor-interacting protein 1 repression 1 TraL PF07178.11 KXH33708.1 - 0.12 12.8 0.5 0.25 11.8 0.5 1.4 1 0 0 1 1 1 0 TraL protein PTP_tm PF18861.1 KXH33708.1 - 0.13 12.2 4.1 0.26 11.3 3.9 1.6 1 1 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J DUF3318 PF11780.8 KXH33708.1 - 0.22 11.4 0.9 0.34 10.9 0.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3318) zf-HIT PF04438.16 KXH33709.1 - 7.2e-09 35.4 10.2 9.9e-09 34.9 10.2 1.2 1 0 0 1 1 1 1 HIT zinc finger zf-MYND PF01753.18 KXH33709.1 - 0.0083 16.2 7.7 0.013 15.6 7.7 1.3 1 0 0 1 1 1 1 MYND finger zf-B_box PF00643.24 KXH33709.1 - 0.12 12.5 8.1 0.17 12.1 8.1 1.2 1 0 0 1 1 1 0 B-box zinc finger PAXIP1_C PF15364.6 KXH33711.1 - 0.0003 21.1 3.7 0.0003 21.1 3.7 1.9 2 0 0 2 2 2 1 PAXIP1-associated-protein-1 C term PTIP binding protein ATHILA PF03078.15 KXH33711.1 - 0.36 9.6 6.7 0.48 9.2 6.7 1.1 1 0 0 1 1 1 0 ATHILA ORF-1 family NOA36 PF06524.12 KXH33711.1 - 1.7 7.9 11.7 2.5 7.4 11.7 1.2 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.12 KXH33711.1 - 1.7 6.7 9.1 2 6.5 9.1 1.1 1 0 0 1 1 1 0 Nop14-like family INO80_Ies4 PF08193.11 KXH33711.1 - 6.6 6.7 11.6 5.9 6.8 1.5 2.1 2 0 0 2 2 2 0 INO80 complex subunit Ies4 Glyco_hydro_63 PF03200.16 KXH33712.1 - 4.1e-07 29.1 9.6 6.7e-06 25.1 0.1 4.3 5 1 0 5 5 5 2 Glycosyl hydrolase family 63 C-terminal domain TTSSLRR PF12468.8 KXH33712.1 - 0.11 12.8 0.1 0.34 11.2 0.1 1.8 1 0 0 1 1 1 0 Type III secretion system leucine rich repeat protein OSCP PF00213.18 KXH33713.1 - 4.8e-49 166.8 0.6 6.6e-49 166.3 0.6 1.2 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit Acyl-CoA_dh_1 PF00441.24 KXH33713.1 - 0.2 11.9 1.8 3.1 8.0 0.1 2.1 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain Mob1_phocein PF03637.17 KXH33714.1 - 1.8e-70 236.4 0.0 2.1e-70 236.1 0.0 1.1 1 0 0 1 1 1 1 Mob1/phocein family Mrx7 PF10906.8 KXH33714.1 - 0.17 12.2 0.3 0.48 10.7 0.2 1.8 2 0 0 2 2 2 0 MIOREX complex component 7 BRK PF07533.16 KXH33715.1 - 0.18 11.5 2.5 4 7.2 0.1 3.1 3 0 0 3 3 3 0 BRK domain LSM PF01423.22 KXH33716.1 - 4.1e-15 55.2 0.0 6.4e-15 54.6 0.0 1.3 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 KXH33716.1 - 0.19 11.4 0.0 0.34 10.6 0.0 1.4 1 0 0 1 1 1 0 Hfq protein NUDIX PF00293.28 KXH33717.1 - 4.4e-18 65.6 1.5 5.4e-18 65.3 1.5 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_2 PF13869.6 KXH33717.1 - 0.032 13.8 0.0 0.041 13.5 0.0 1.2 1 0 0 1 1 1 0 Nucleotide hydrolase Methyltransf_23 PF13489.6 KXH33770.1 - 1.3e-10 41.3 0.0 1.8e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH33770.1 - 0.0001 22.9 0.0 0.00033 21.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH33770.1 - 0.0032 17.3 0.1 0.038 13.8 0.1 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH33770.1 - 0.049 14.4 0.0 0.38 11.5 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 KXH33770.1 - 0.082 12.5 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain DUF4357 PF14267.6 KXH33770.1 - 0.16 12.0 0.1 0.32 11.0 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4357) DUF1708 PF08101.11 KXH33772.1 - 2.1e-180 600.5 0.0 3.9e-180 599.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) Asn_synthase PF00733.21 KXH33773.1 - 9.2e-64 216.3 0.0 1.3e-63 215.8 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.6 KXH33773.1 - 2.7e-35 120.9 0.0 5.1e-35 120.1 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 KXH33773.1 - 3.7e-33 114.6 0.0 9.1e-33 113.3 0.0 1.7 2 0 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.8 KXH33773.1 - 1.7e-06 27.7 0.0 3.7e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.17 KXH33773.1 - 0.055 12.6 0.0 0.089 11.9 0.0 1.3 1 0 0 1 1 1 0 NAD synthase tRNA_Me_trans PF03054.16 KXH33773.1 - 0.15 10.8 0.0 0.23 10.2 0.0 1.2 1 0 0 1 1 1 0 tRNA methyl transferase MBOAT PF03062.19 KXH33774.1 - 1.8e-49 168.9 14.7 1.8e-49 168.9 14.7 1.9 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family XPA_N PF01286.18 KXH33775.1 - 0.23 11.5 0.0 0.44 10.6 0.0 1.4 1 0 0 1 1 1 0 XPA protein N-terminal EzrA PF06160.12 KXH33777.1 - 0.036 12.2 3.3 0.059 11.5 3.3 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA DivIVA PF05103.13 KXH33777.1 - 0.17 12.0 1.9 0.59 10.2 1.1 2.2 1 1 0 1 1 1 0 DivIVA protein Zip PF02535.22 KXH33777.1 - 3.1 6.9 5.9 5.4 6.1 5.9 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter adh_short PF00106.25 KXH33778.1 - 1.1e-13 51.1 0.3 1.2e-13 50.9 0.3 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXH33778.1 - 3.1e-08 33.4 0.7 3.5e-08 33.3 0.7 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH33778.1 - 1e-05 25.5 0.2 1.1e-05 25.4 0.2 1.0 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXH33778.1 - 0.0016 18.0 0.1 0.0017 17.9 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXH33778.1 - 0.074 12.4 0.0 0.09 12.2 0.0 1.1 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase DPBB_1 PF03330.18 KXH33789.1 - 0.026 14.8 0.2 0.051 13.8 0.2 1.6 1 1 0 1 1 1 0 Lytic transglycolase Totivirus_coat PF05518.11 KXH33789.1 - 9.4 4.1 15.6 13 3.7 15.6 1.1 1 0 0 1 1 1 0 Totivirus coat protein DAO PF01266.24 KXH33790.1 - 1.2e-39 137.0 3.9 1.8e-39 136.4 3.9 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXH33790.1 - 0.00037 20.6 0.3 0.0011 19.1 0.3 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain eIF-5_eIF-2B PF01873.17 KXH33791.1 - 1.7e-41 140.8 0.7 2.9e-41 140.0 0.7 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 DUF3621 PF12285.8 KXH33791.1 - 0.033 14.5 0.9 4.5 7.7 0.1 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3621) MYT1 PF08474.11 KXH33791.1 - 0.06 13.3 1.7 0.86 9.5 0.1 2.5 1 1 1 2 2 2 0 Myelin transcription factor 1 Arc_trans_TRASH PF08394.10 KXH33791.1 - 0.9 9.9 7.0 1.9 8.9 0.2 2.5 1 1 1 2 2 2 0 Archaeal TRASH domain MARVEL PF01284.23 KXH33793.1 - 4.5e-22 78.6 15.7 5.4e-22 78.4 15.7 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF1712 PF08217.11 KXH33794.1 - 1.2e-15 57.1 0.0 5.7e-13 48.2 0.0 2.4 2 0 0 2 2 2 2 Fungal domain of unknown function (DUF1712) DNA_pol_E_B PF04042.16 KXH33795.1 - 1.2e-63 214.3 0.0 1.6e-63 213.9 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Pkinase PF00069.25 KXH33797.1 - 5.1e-74 249.0 0.0 6.9e-74 248.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXH33797.1 - 5e-37 127.6 0.0 7.7e-37 127.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase AdenylateSensor PF16579.5 KXH33797.1 - 1.8e-18 67.1 0.5 4.8e-10 39.9 0.1 3.1 2 1 0 2 2 2 2 Adenylate sensor of SNF1-like protein kinase UBA_2 PF08587.11 KXH33797.1 - 1.6e-15 56.9 0.2 3.4e-15 55.9 0.2 1.6 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.6 KXH33797.1 - 6.4e-05 22.4 0.0 0.00011 21.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KXH33797.1 - 0.0013 18.4 0.0 0.0023 17.5 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 KXH33797.1 - 0.0027 16.7 0.1 0.0058 15.6 0.1 1.6 2 0 0 2 2 2 1 Haspin like kinase domain YukC PF10140.9 KXH33797.1 - 0.0093 14.8 0.1 0.015 14.2 0.1 1.2 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC APH PF01636.23 KXH33797.1 - 0.089 12.7 0.7 0.32 10.9 0.4 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family PrsW-protease PF13367.6 KXH33798.1 - 0.089 12.2 0.1 0.11 11.9 0.1 1.2 1 0 0 1 1 1 0 PrsW family intramembrane metalloprotease PNGaseA PF12222.8 KXH33800.1 - 4.5e-153 510.2 0.2 2e-101 340.0 0.1 2.1 2 0 0 2 2 2 2 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A DUF1279 PF06916.13 KXH33802.1 - 2.6e-25 88.8 0.3 8.7e-25 87.1 0.3 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1279) EOS1 PF12326.8 KXH33802.1 - 0.084 12.8 2.7 0.51 10.3 0.1 2.2 1 1 1 2 2 2 0 N-glycosylation protein His_Phos_2 PF00328.22 KXH33803.1 - 6.7e-51 173.8 0.0 8e-51 173.6 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) TauD PF02668.16 KXH33804.1 - 1.1e-27 97.5 0.3 1.8e-27 96.8 0.3 1.3 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 KXH33804.1 - 0.022 13.9 0.1 0.035 13.2 0.1 1.2 1 0 0 1 1 1 0 CsiD zf-C2H2 PF00096.26 KXH33847.1 - 0.00027 21.2 12.8 0.007 16.8 2.1 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type Integrin_B_tail PF07965.12 KXH33847.1 - 0.031 14.8 0.9 0.054 14.0 0.2 1.7 1 1 1 2 2 2 0 Integrin beta tail domain zf-H2C2_2 PF13465.6 KXH33847.1 - 0.035 14.6 2.3 0.035 14.6 2.3 2.8 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 KXH33847.1 - 0.036 14.9 10.4 0.23 12.4 1.5 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-met PF12874.7 KXH33847.1 - 0.21 12.0 7.7 0.46 10.9 0.4 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Acetate_kinase PF00871.17 KXH33848.1 - 1.1e-91 307.4 0.0 1.4e-91 307.1 0.0 1.0 1 0 0 1 1 1 1 Acetokinase family Sugar_tr PF00083.24 KXH33850.1 - 1.5e-32 113.1 22.1 8.7e-19 67.7 9.4 2.5 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KXH33850.1 - 1.7e-22 79.8 25.1 1.9e-16 60.0 14.1 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily GST_N_3 PF13417.6 KXH33851.1 - 1.2e-16 60.9 0.0 2.5e-16 59.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KXH33851.1 - 6.3e-11 42.4 0.0 1.3e-10 41.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KXH33851.1 - 9.7e-09 35.5 0.0 2.1e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_5 PF16865.5 KXH33851.1 - 1.7e-05 25.4 0.0 3.7e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KXH33851.1 - 3.5e-05 23.7 0.2 7.6e-05 22.7 0.2 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KXH33851.1 - 0.032 14.4 0.0 0.15 12.2 0.0 2.1 3 0 0 3 3 3 0 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 KXH33851.1 - 0.079 13.2 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin GST_C PF00043.25 KXH33851.1 - 0.16 12.2 0.0 0.43 10.8 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Fungal_trans PF04082.18 KXH33852.1 - 2.3e-20 72.7 0.0 4.7e-20 71.7 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH33852.1 - 4.8e-09 36.2 8.4 1e-08 35.1 8.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.32 KXH33853.1 - 4.7e-20 71.5 7.0 1.4e-05 25.7 0.4 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXH33853.1 - 1.3e-14 54.3 0.0 0.017 15.4 0.0 5.4 1 1 5 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KXH33853.1 - 0.0044 15.7 0.4 0.14 10.8 0.0 2.3 1 1 0 2 2 2 1 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KXH33853.1 - 0.024 13.6 0.1 4.5 6.1 0.0 2.7 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KXH33853.1 - 0.029 14.3 0.1 1.6 8.6 0.0 3.1 2 1 1 4 4 4 0 Eukaryotic translation initiation factor eIF2A DUF1513 PF07433.11 KXH33853.1 - 0.11 11.5 0.0 1.4 7.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1513) Coatomer_WDAD PF04053.14 KXH33853.1 - 0.23 10.5 0.0 0.32 10.0 0.0 1.3 1 0 0 1 1 1 0 Coatomer WD associated region RIC1 PF07064.13 KXH33854.1 - 2.1e-96 322.2 0.0 3e-96 321.7 0.0 1.2 1 0 0 1 1 1 1 RIC1 ANAPC4_WD40 PF12894.7 KXH33854.1 - 0.07 13.4 0.0 4.2 7.8 0.0 3.6 3 2 2 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KXH33854.1 - 0.11 13.4 0.3 66 4.6 0.0 4.3 4 0 0 4 4 4 0 WD domain, G-beta repeat CK_II_beta PF01214.18 KXH33855.1 - 1.2e-76 256.7 0.1 1.4e-76 256.3 0.1 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit PAP2 PF01569.21 KXH33856.1 - 1.3e-22 80.0 0.5 1.3e-22 80.0 0.5 2.4 2 1 0 2 2 2 1 PAP2 superfamily DUF4386 PF14329.6 KXH33856.1 - 0.033 14.1 2.3 0.073 12.9 0.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4386) Polysacc_deac_1 PF01522.21 KXH33857.1 - 9.5e-25 86.9 0.0 2.6e-24 85.5 0.0 1.7 2 0 0 2 2 2 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.19 KXH33857.1 - 1.5e-22 79.8 66.6 5.3e-09 36.4 14.3 3.6 3 0 0 3 3 3 3 Chitin recognition protein Cyclin_N PF00134.23 KXH33858.1 - 5.1e-44 149.1 0.0 2e-43 147.1 0.0 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KXH33858.1 - 3.1e-34 117.6 0.0 5.2e-34 116.9 0.0 1.4 1 0 0 1 1 1 1 Cyclin, C-terminal domain Ribosomal_L2_C PF03947.18 KXH33859.1 - 1.6e-51 173.8 2.6 3.6e-51 172.6 1.9 2.1 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 KXH33859.1 - 1.4e-25 89.0 1.2 2.1e-25 88.5 0.4 1.7 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain OHCU_decarbox PF09349.10 KXH33860.1 - 0.0099 16.4 0.6 0.012 16.1 0.6 1.1 1 0 0 1 1 1 1 OHCU decarboxylase PEP-utilisers_N PF05524.13 KXH33860.1 - 0.015 15.4 0.1 0.021 15.0 0.1 1.3 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal GrpE PF01025.19 KXH33860.1 - 0.021 14.5 0.4 0.025 14.3 0.4 1.1 1 0 0 1 1 1 0 GrpE RNase_H2_suC PF08615.11 KXH33860.1 - 0.049 13.8 0.2 0.069 13.3 0.2 1.2 1 0 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Peptidase_S49_N PF08496.10 KXH33860.1 - 0.22 11.6 2.4 0.26 11.3 2.4 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Borealin PF10512.9 KXH33861.1 - 0.042 13.8 0.4 0.045 13.7 0.4 1.1 1 0 0 1 1 1 0 Cell division cycle-associated protein 8 Ion_trans PF00520.31 KXH33862.1 - 1.3e-121 404.5 78.9 1.4e-42 145.6 11.0 4.7 4 1 0 4 4 4 4 Ion transport protein JSRP PF15312.6 KXH33862.1 - 0.043 13.7 0.1 0.16 11.9 0.1 2.0 1 0 0 1 1 1 0 Junctional sarcoplasmic reticulum protein GPHH PF16905.5 KXH33862.1 - 0.097 12.5 0.0 0.22 11.3 0.0 1.7 1 0 0 1 1 1 0 Voltage-dependent L-type calcium channel, IQ-associated PHD PF00628.29 KXH33863.1 - 1.2e-09 37.9 9.1 2.5e-09 36.9 9.1 1.6 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 KXH33863.1 - 0.0086 15.6 6.0 0.016 14.7 6.0 1.5 1 0 0 1 1 1 1 PHD-finger Tti2 PF10521.9 KXH33863.1 - 0.17 11.4 7.2 0.14 11.6 5.5 1.6 2 0 0 2 2 2 0 Tti2 family HMG_box PF00505.19 KXH33864.1 - 1.2e-13 51.3 0.3 2.6e-12 47.0 0.1 2.4 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KXH33864.1 - 0.00038 21.0 0.0 0.00099 19.7 0.0 1.7 1 0 0 1 1 1 1 HMG-box domain MATalpha_HMGbox PF04769.12 KXH33864.1 - 0.0015 17.9 0.1 0.0021 17.4 0.1 1.3 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 HMG-box ARHGEF5_35 PF15441.6 KXH33864.1 - 1.7 7.5 6.6 0.11 11.5 0.6 1.8 2 0 0 2 2 2 0 Rho guanine nucleotide exchange factor 5/35 MMgT PF10270.9 KXH33865.1 - 1.4e-34 118.4 0.0 1.6e-34 118.2 0.0 1.0 1 0 0 1 1 1 1 Membrane magnesium transporter MutS_V PF00488.21 KXH33866.1 - 6e-47 160.1 0.1 1.2e-46 159.1 0.1 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KXH33866.1 - 1.3e-19 71.1 0.1 2.4e-19 70.3 0.1 1.5 1 0 0 1 1 1 1 MutS domain III Med28 PF11594.8 KXH33866.1 - 0.007 16.4 0.8 0.023 14.8 0.7 1.8 2 0 0 2 2 2 1 Mediator complex subunit 28 CorA PF01544.18 KXH33867.1 - 8.2e-14 51.6 0.2 3e-13 49.7 0.2 1.9 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein WD40 PF00400.32 KXH33870.1 - 4.5e-12 46.3 4.3 0.21 12.5 0.1 6.5 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXH33870.1 - 0.02 15.2 0.1 3 8.2 0.0 3.3 3 2 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain DUF2020 PF09449.10 KXH33870.1 - 0.07 13.0 0.1 1.4 8.7 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF2020) A_deaminase PF00962.22 KXH33871.1 - 1.3e-122 409.3 0.1 1.8e-122 408.7 0.1 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase UAA PF08449.11 KXH33871.1 - 2.1e-90 303.0 3.6 3.1e-90 302.4 3.6 1.2 1 0 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.15 KXH33871.1 - 9.8e-07 28.2 0.1 1.9e-06 27.3 0.1 1.4 1 0 0 1 1 1 1 Nucleotide-sugar transporter DUF4199 PF13858.6 KXH33871.1 - 0.044 14.2 0.2 1.1 9.6 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) SHD1 PF03983.12 KXH33872.1 - 4.8e-35 119.2 0.0 8.2e-35 118.5 0.0 1.4 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_9 PF14604.6 KXH33872.1 - 1.8e-32 110.9 10.9 3e-11 43.0 0.3 3.7 4 0 0 4 4 4 3 Variant SH3 domain SH3_1 PF00018.28 KXH33872.1 - 4.2e-32 109.5 9.2 9.9e-13 47.5 0.2 4.2 4 0 0 4 4 4 3 SH3 domain SH3_2 PF07653.17 KXH33872.1 - 3.3e-22 77.9 0.4 6.8e-07 28.9 0.0 4.4 4 0 0 4 4 4 3 Variant SH3 domain DUF1720 PF08226.11 KXH33872.1 - 1.5e-06 28.5 51.3 3.6e-06 27.3 27.9 6.3 3 2 3 6 6 6 2 Domain of unknown function (DUF1720) SH3_3 PF08239.11 KXH33872.1 - 4.2e-05 23.8 6.4 0.015 15.6 1.2 3.4 3 0 0 3 3 3 2 Bacterial SH3 domain SAM_4 PF18017.1 KXH33872.1 - 0.0011 18.9 0.0 0.0024 17.8 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_10 PF17902.1 KXH33872.1 - 0.064 13.3 0.3 0.27 11.3 0.1 2.2 2 0 0 2 2 2 0 SH3 domain TRAM_LAG1_CLN8 PF03798.16 KXH33873.1 - 1.4e-48 165.3 15.5 1.4e-48 165.3 15.5 1.6 2 0 0 2 2 2 1 TLC domain Dor1 PF04124.12 KXH33874.1 - 9.8e-56 188.9 2.1 5.5e-45 153.5 2.9 2.1 2 0 0 2 2 2 2 Dor1-like family AAA_21 PF13304.6 KXH33875.1 - 8.4 6.1 7.9 15 5.3 7.9 1.5 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Prefoldin_2 PF01920.20 KXH33876.1 - 1.4e-11 44.3 5.4 1.7e-05 24.7 0.1 2.3 2 1 0 2 2 2 2 Prefoldin subunit TMF_TATA_bd PF12325.8 KXH33876.1 - 0.00089 19.5 4.0 0.0066 16.6 0.2 2.1 2 0 0 2 2 2 1 TATA element modulatory factor 1 TATA binding DUF641 PF04859.12 KXH33876.1 - 0.0065 16.8 1.3 0.43 10.9 0.0 2.1 2 0 0 2 2 2 1 Plant protein of unknown function (DUF641) PKcGMP_CC PF16808.5 KXH33876.1 - 0.37 10.7 3.0 0.47 10.3 0.5 2.1 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase CENP-H PF05837.12 KXH33876.1 - 0.4 11.1 6.7 2.9 8.3 0.3 2.1 2 0 0 2 2 2 0 Centromere protein H (CENP-H) FliJ PF02050.16 KXH33876.1 - 0.56 10.4 9.6 1.8 8.8 4.1 2.1 2 0 0 2 2 2 0 Flagellar FliJ protein DUF16 PF01519.16 KXH33876.1 - 0.83 10.2 4.8 2.6 8.6 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function DUF16 THOC7 PF05615.13 KXH33876.1 - 1.6 9.0 8.0 7.7 6.8 2.6 2.2 2 0 0 2 2 2 0 Tho complex subunit 7 ABC_tran_CTD PF16326.5 KXH33876.1 - 9.4 6.6 8.6 21 5.4 0.5 2.2 2 0 0 2 2 2 0 ABC transporter C-terminal domain Ceramidase PF05875.12 KXH33877.1 - 1.2e-90 303.6 7.2 1.4e-90 303.3 7.2 1.0 1 0 0 1 1 1 1 Ceramidase ATP-synt_I PF03899.15 KXH33877.1 - 5.4 7.4 13.1 2.6 8.5 3.6 3.0 2 1 0 3 3 3 0 ATP synthase I chain TMF_TATA_bd PF12325.8 KXH33878.1 - 3.5e-41 140.0 7.0 3.5e-41 140.0 7.0 6.5 3 1 1 5 5 5 2 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.8 KXH33878.1 - 3.5e-12 46.2 4.3 3.5e-12 46.2 4.3 8.1 5 2 3 8 8 8 1 TATA element modulatory factor 1 DNA binding ATG16 PF08614.11 KXH33878.1 - 8.6e-05 22.9 3.5 8.6e-05 22.9 3.5 6.3 3 1 4 7 7 7 2 Autophagy protein 16 (ATG16) DUF948 PF06103.11 KXH33878.1 - 0.14 12.5 16.1 0.7 10.2 0.9 5.0 5 0 0 5 5 5 0 Bacterial protein of unknown function (DUF948) Cytochrom_NNT PF03264.14 KXH33878.1 - 0.2 11.4 1.2 0.62 9.7 1.2 1.8 1 0 0 1 1 1 0 NapC/NirT cytochrome c family, N-terminal region Holin_BhlA PF10960.8 KXH33878.1 - 0.2 11.6 0.1 0.2 11.6 0.1 2.8 3 0 0 3 3 3 0 BhlA holin family CENP-F_leu_zip PF10473.9 KXH33878.1 - 0.79 9.7 63.9 0.37 10.8 7.4 5.5 4 1 0 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 COG5 PF10392.9 KXH33878.1 - 1.1 9.5 17.0 0.069 13.3 0.6 4.0 3 1 1 4 4 4 0 Golgi transport complex subunit 5 Ank_5 PF13857.6 KXH33879.1 - 2.3e-39 132.9 3.7 1.3e-08 34.9 0.1 5.4 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXH33879.1 - 1.9e-37 127.7 4.2 1.7e-12 47.8 0.7 3.5 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXH33879.1 - 7.9e-31 106.0 3.3 9.9e-10 38.8 0.2 5.1 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXH33879.1 - 3e-28 94.7 0.2 0.0018 18.6 0.0 6.4 6 0 0 6 6 6 6 Ankyrin repeat Ank PF00023.30 KXH33879.1 - 3.9e-22 77.6 6.5 6.4e-05 23.2 0.1 6.3 6 0 0 6 6 6 6 Ankyrin repeat WD40 PF00400.32 KXH33880.1 - 5.9e-45 150.4 17.6 6.7e-09 36.2 0.3 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXH33880.1 - 3.6e-05 24.0 0.2 9.7 6.6 0.0 5.0 1 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KXH33880.1 - 0.025 13.2 2.9 12 4.4 0.0 4.2 1 1 4 5 5 5 0 Nucleoporin Nup120/160 AAA PF00004.29 KXH33881.1 - 1.7e-17 64.1 0.0 2.2e-16 60.5 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_10 PF17872.1 KXH33881.1 - 3e-11 43.3 0.1 8.9e-11 41.8 0.1 1.7 1 0 0 1 1 1 1 AAA lid domain AAA_16 PF13191.6 KXH33881.1 - 2.3e-10 41.1 0.0 2.5e-09 37.7 0.0 2.6 2 1 0 2 2 1 1 AAA ATPase domain AAA_22 PF13401.6 KXH33881.1 - 1.5e-09 38.2 0.0 5e-08 33.3 0.0 2.7 3 0 0 3 3 3 1 AAA domain BAH PF01426.18 KXH33881.1 - 4.2e-09 36.3 0.0 1.2e-08 34.9 0.0 1.8 2 0 0 2 2 2 1 BAH domain AAA_19 PF13245.6 KXH33881.1 - 0.0014 18.9 0.0 0.0047 17.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 KXH33881.1 - 0.0015 18.5 0.0 0.036 14.0 0.0 2.3 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea DUF2075 PF09848.9 KXH33881.1 - 0.009 15.3 0.0 0.015 14.5 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.6 KXH33881.1 - 0.013 15.3 0.0 0.031 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KXH33881.1 - 0.014 15.3 0.0 0.028 14.3 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_18 PF13238.6 KXH33881.1 - 0.026 15.1 0.0 0.062 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KXH33881.1 - 0.053 13.9 0.0 0.24 11.8 0.0 2.1 2 0 0 2 2 2 0 RNA helicase AAA_32 PF13654.6 KXH33881.1 - 0.064 12.0 0.0 0.097 11.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KXH33881.1 - 0.069 13.3 0.1 6.5 6.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF1515 PF07439.11 KXH33883.1 - 0.063 13.3 0.3 0.095 12.7 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) Mod_r PF07200.13 KXH33883.1 - 0.083 13.0 5.5 0.042 14.0 3.1 1.6 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Utp8 PF10395.9 KXH33884.1 - 4.4e-08 32.1 0.6 0.00034 19.3 0.0 3.3 4 0 0 4 4 4 3 Utp8 family AAA PF00004.29 KXH33885.1 - 6.7e-08 33.0 0.9 7.7e-07 29.6 0.9 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KXH33885.1 - 0.00084 19.6 0.7 0.0058 16.9 0.1 2.5 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KXH33885.1 - 0.00085 19.7 0.0 0.0028 18.0 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain Rad17 PF03215.15 KXH33885.1 - 0.0025 17.7 0.0 0.074 13.0 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_18 PF13238.6 KXH33885.1 - 0.0038 17.8 0.0 0.012 16.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.13 KXH33885.1 - 0.016 14.4 0.0 0.026 13.7 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain TsaE PF02367.17 KXH33885.1 - 0.037 14.0 0.0 0.11 12.5 0.0 1.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE T2SSE PF00437.20 KXH33885.1 - 0.054 12.5 0.0 0.13 11.2 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_14 PF13173.6 KXH33885.1 - 0.16 12.0 0.0 0.47 10.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.12 KXH33885.1 - 0.2 11.4 0.0 0.39 10.4 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AT_hook PF02178.19 KXH33885.1 - 0.39 10.7 6.5 2 8.6 6.5 2.4 1 0 0 1 1 1 0 AT hook motif Pkinase PF00069.25 KXH33887.1 - 1.3e-11 44.4 0.0 1.9e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXH33887.1 - 9e-06 25.2 0.0 1.4e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase B2 PF11473.8 KXH33887.1 - 0.018 14.8 0.0 0.039 13.7 0.0 1.5 1 0 0 1 1 1 0 RNA binding protein B2 Kinase-like PF14531.6 KXH33887.1 - 0.04 13.2 0.0 0.056 12.7 0.0 1.4 1 0 0 1 1 1 0 Kinase-like EF-hand_6 PF13405.6 KXH34062.1 - 4.7e-12 44.8 0.3 1.3e-05 24.7 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 KXH34062.1 - 3.1e-10 38.8 1.4 0.00043 19.6 0.1 2.4 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 KXH34062.1 - 9e-08 32.5 0.0 0.011 16.2 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 KXH34062.1 - 4e-06 26.1 3.9 0.0067 15.9 0.4 2.4 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 KXH34062.1 - 4e-06 26.6 0.4 0.0071 16.2 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 KXH34062.1 - 0.00049 20.4 0.0 0.63 10.4 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain ORC6 PF05460.13 KXH34062.1 - 0.79 8.9 5.1 1.4 8.1 5.1 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Afi1 PF07792.12 KXH34063.1 - 4.1e-47 160.0 0.2 6.8e-47 159.3 0.2 1.4 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking SPA PF08616.10 KXH34063.1 - 6.6e-36 122.7 0.0 1.2e-35 121.9 0.0 1.4 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.9 KXH34063.1 - 8.7e-08 31.2 0.1 0.014 14.1 0.0 3.9 3 1 1 4 4 4 2 Transport protein Avl9 Cwf_Cwc_15 PF04889.12 KXH34063.1 - 0.0024 17.7 3.5 0.0045 16.8 3.5 1.3 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein DUF2347 PF09804.9 KXH34063.1 - 0.036 13.7 0.0 0.12 11.9 0.0 1.9 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) Anillin_N PF16018.5 KXH34063.1 - 0.066 13.8 0.4 0.25 12.0 0.4 2.0 1 0 0 1 1 1 0 Anillin N-terminus Astro_capsid_p PF12226.8 KXH34063.1 - 1.5 7.9 3.6 2.3 7.3 3.6 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein QWRF PF04484.12 KXH34063.1 - 2.7 7.6 5.0 4.2 7.0 5.0 1.2 1 0 0 1 1 1 0 QWRF family SOG2 PF10428.9 KXH34063.1 - 6.3 5.9 9.3 8.9 5.4 9.3 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Esterase PF00756.20 KXH34064.1 - 1.7e-51 175.3 0.0 2e-51 175.1 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Esterase_phd PF10503.9 KXH34064.1 - 1.8e-05 24.4 0.1 0.00013 21.5 0.1 2.0 1 1 0 1 1 1 1 Esterase PHB depolymerase Chlorophyllase2 PF12740.7 KXH34064.1 - 0.0015 17.5 0.0 0.0029 16.6 0.0 1.5 1 1 0 1 1 1 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 KXH34064.1 - 0.0042 16.4 0.0 0.0066 15.7 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KXH34064.1 - 0.0044 16.5 0.0 0.0083 15.6 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 KXH34064.1 - 0.011 15.5 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 KXH34064.1 - 0.033 14.8 0.0 0.042 14.4 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Lipase_3 PF01764.25 KXH34064.1 - 0.061 13.2 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) PAF-AH_p_II PF03403.13 KXH34064.1 - 0.065 11.7 0.0 0.12 10.9 0.0 1.4 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase PF07224.11 KXH34064.1 - 0.092 11.7 0.0 0.23 10.4 0.0 1.6 2 0 0 2 2 2 0 Chlorophyllase Zip PF02535.22 KXH34066.1 - 1e-25 90.7 12.6 5.8e-23 81.6 8.4 2.1 2 0 0 2 2 2 2 ZIP Zinc transporter SelP_N PF04592.14 KXH34066.1 - 0.16 11.4 22.7 0.061 12.7 16.1 2.4 2 0 0 2 2 2 0 Selenoprotein P, N terminal region DUF2090 PF09863.9 KXH34066.1 - 0.17 10.8 0.0 0.28 10.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2090) Endonuclease_NS PF01223.23 KXH34067.1 - 1.4e-67 227.9 0.0 1.8e-67 227.5 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease WD40 PF00400.32 KXH34068.1 - 4.9e-32 109.5 26.6 4e-05 24.3 0.0 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXH34068.1 - 2.8e-14 53.2 0.1 0.018 15.3 0.0 6.1 2 1 5 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KXH34068.1 - 0.081 12.8 0.0 3.9 7.3 0.0 2.8 1 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Frtz PF11768.8 KXH34068.1 - 0.17 10.1 0.0 0.29 9.4 0.0 1.3 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz Ge1_WD40 PF16529.5 KXH34068.1 - 0.19 10.6 0.3 17 4.3 0.0 3.1 1 1 2 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein MBOAT PF03062.19 KXH34069.1 - 1.2e-17 64.3 17.7 1.9e-17 63.7 17.7 1.3 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 KXH34069.1 - 0.007 16.6 1.7 0.018 15.3 1.7 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family ICMT PF04140.14 KXH34070.1 - 1e-27 96.4 0.9 2.2e-27 95.3 0.9 1.5 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KXH34070.1 - 3.1e-13 50.0 3.7 3.1e-13 50.0 3.7 2.0 2 0 0 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.12 KXH34070.1 - 0.00026 20.6 0.6 0.00042 19.9 0.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) NnrU PF07298.11 KXH34070.1 - 0.00031 20.3 0.9 0.00031 20.3 0.9 1.8 1 1 0 2 2 2 1 NnrU protein Steroid_dh PF02544.16 KXH34070.1 - 0.0021 18.1 3.1 0.0025 17.8 2.2 1.6 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase CCB1 PF12046.8 KXH34070.1 - 0.34 10.3 6.5 2.3 7.5 0.1 2.4 2 1 0 2 2 2 0 Cofactor assembly of complex C subunit B Hexapep_2 PF14602.6 KXH34071.1 - 1.7e-13 50.0 10.1 4.6e-10 39.1 3.6 3.2 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Hexapep PF00132.24 KXH34071.1 - 1.1e-12 47.1 10.1 2.8e-09 36.3 3.8 3.3 3 0 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Mac PF12464.8 KXH34071.1 - 4.4e-09 36.4 0.1 7.1e-09 35.8 0.1 1.3 1 0 0 1 1 1 1 Maltose acetyltransferase Tmemb_170 PF10190.9 KXH34072.1 - 5e-25 87.9 15.0 5.8e-25 87.7 15.0 1.1 1 0 0 1 1 1 1 Putative transmembrane protein 170 DUF4383 PF14325.6 KXH34072.1 - 0.26 11.6 11.0 0.86 9.9 10.9 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4383) bZIP_1 PF00170.21 KXH34076.1 - 7e-06 26.1 6.6 7e-06 26.1 6.6 1.7 2 0 0 2 2 2 1 bZIP transcription factor ComFB PF10719.9 KXH34076.1 - 0.23 11.6 1.5 0.44 10.7 1.5 1.3 1 0 0 1 1 1 0 Late competence development protein ComFB DUF5595 PF18077.1 KXH34076.1 - 0.25 11.4 1.0 0.34 11.0 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5595) bZIP_2 PF07716.15 KXH34076.1 - 2.3 8.4 10.1 0.65 10.1 6.4 2.0 2 0 0 2 2 2 0 Basic region leucine zipper CMS1 PF14617.6 KXH34179.1 - 3.6e-12 46.2 0.0 3.7e-12 46.1 0.0 1.0 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit RhoGAP PF00620.27 KXH34180.1 - 9.1e-48 161.9 0.0 2e-47 160.8 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.23 KXH34180.1 - 2.5e-11 43.7 0.8 6.8e-11 42.3 0.8 1.8 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain DUF4407 PF14362.6 KXH34180.1 - 0.034 13.5 5.2 0.058 12.7 5.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) OmpH PF03938.14 KXH34180.1 - 0.22 11.8 11.4 0.053 13.9 7.1 2.1 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) p450 PF00067.22 KXH34181.1 - 2.3e-77 260.7 0.0 2.7e-77 260.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ISN1 PF06437.11 KXH34182.1 - 8.7e-80 268.6 0.0 9.6e-80 268.5 0.0 1.0 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase DUF3175 PF11373.8 KXH34182.1 - 0.0019 18.3 0.0 0.0039 17.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3175) PUL PF08324.11 KXH34182.1 - 0.083 12.1 0.1 0.099 11.9 0.1 1.1 1 0 0 1 1 1 0 PUL domain PAP_assoc PF03828.19 KXH34189.1 - 1.4e-12 47.7 0.0 2.5e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 KXH34189.1 - 2.4e-05 24.5 0.0 5.3e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain DAD PF02109.16 KXH34189.1 - 0.069 13.5 0.0 0.19 12.0 0.0 1.7 2 0 0 2 2 2 0 DAD family Sugar_tr PF00083.24 KXH34190.1 - 4.8e-110 368.5 19.6 6.3e-110 368.1 19.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH34190.1 - 8.4e-22 77.6 23.5 8.4e-22 77.6 23.5 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_3 PF05977.13 KXH34190.1 - 0.27 9.6 10.1 0.036 12.5 5.8 1.6 2 0 0 2 2 2 0 Transmembrane secretion effector DUF554 PF04474.12 KXH34190.1 - 1.1 8.7 9.1 0.042 13.3 1.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF554) PAP2 PF01569.21 KXH34190.1 - 2.8 7.7 10.1 1.6 8.5 3.8 2.7 2 0 0 2 2 2 0 PAP2 superfamily SMI1_KNR4 PF09346.10 KXH34191.1 - 0.0023 18.3 0.0 0.029 14.7 0.0 2.4 2 1 0 2 2 2 1 SMI1 / KNR4 family (SUKH-1) WSC PF01822.19 KXH34192.1 - 4.6e-15 55.6 9.8 8.9e-15 54.7 9.8 1.5 1 0 0 1 1 1 1 WSC domain Glyco_hydro_43 PF04616.14 KXH34194.1 - 8.2e-36 123.8 2.2 1.4e-35 123.0 2.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 KXH34194.1 - 7.9e-11 42.1 0.0 1.1e-10 41.6 0.0 1.2 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain Glyco_hydro_43 PF04616.14 KXH34195.1 - 2.4e-35 122.3 4.2 2.4e-35 122.3 4.2 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 KXH34195.1 - 1e-23 84.1 0.0 1.5e-23 83.6 0.0 1.2 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain DIM PF08194.12 KXH34196.1 - 0.33 11.2 1.9 0.6 10.4 1.9 1.4 1 0 0 1 1 1 0 DIM protein NAD_binding_10 PF13460.6 KXH34197.1 - 1.9e-14 54.0 0.0 3.3e-14 53.2 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KXH34197.1 - 2.1e-06 27.5 0.0 2.9e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.24 KXH34197.1 - 5.3e-05 23.6 0.0 8.5e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KXH34197.1 - 0.031 13.3 0.0 0.039 12.9 0.0 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KXH34197.1 - 0.16 11.4 0.0 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family MFS_1 PF07690.16 KXH34198.1 - 2.5e-22 79.3 66.7 2.6e-13 49.6 34.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KXH34198.1 - 5e-05 22.0 13.1 5e-05 22.0 13.1 2.5 3 0 0 3 3 3 2 MFS/sugar transport protein MFS_1 PF07690.16 KXH34199.1 - 2.9e-32 112.0 25.1 5.3e-32 111.1 25.1 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily Phage_holin_2_4 PF16082.5 KXH34199.1 - 0.0057 16.4 0.9 0.43 10.3 0.0 2.8 2 0 0 2 2 2 1 Bacteriophage holin family, superfamily II-like SpoVAB PF13782.6 KXH34199.1 - 0.15 12.4 6.9 0.034 14.4 2.2 2.3 3 0 0 3 3 3 0 Stage V sporulation protein AB CBM_4_9 PF02018.17 KXH34200.1 - 5e-05 23.6 0.0 9.4e-05 22.7 0.0 1.4 1 1 0 1 1 1 1 Carbohydrate binding domain Peptidase_M43 PF05572.13 KXH34201.1 - 1.9e-09 37.6 0.0 4.7e-09 36.3 0.0 1.6 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 KXH34201.1 - 4.5e-05 23.7 0.2 0.00014 22.0 0.2 1.8 1 1 0 1 1 1 1 Metallo-peptidase family M12 Astacin PF01400.24 KXH34201.1 - 0.01 15.5 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 0 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.24 KXH34201.1 - 0.016 15.0 0.0 0.024 14.5 0.0 1.2 1 0 0 1 1 1 0 Matrixin Reprolysin_3 PF13582.6 KXH34201.1 - 0.017 15.6 0.1 0.026 15.0 0.1 1.5 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KXH34201.1 - 0.021 14.5 0.0 0.037 13.7 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like RGS PF00615.19 KXH34202.1 - 4.1e-05 23.8 0.0 0.00043 20.5 0.0 2.1 2 0 0 2 2 2 1 Regulator of G protein signaling domain Abhydrolase_6 PF12697.7 KXH34203.1 - 1.6e-07 32.1 0.7 5.1e-06 27.2 0.7 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family gpW PF02831.15 KXH34203.1 - 0.35 10.8 2.0 4.3 7.3 0.2 2.4 2 0 0 2 2 2 0 gpW Herpes_UL3 PF03369.13 KXH34204.1 - 0.12 13.0 2.3 0.27 11.8 1.2 1.9 2 0 0 2 2 2 0 Herpesvirus UL3 protein Rotamase_2 PF13145.6 KXH34204.1 - 0.18 12.6 6.3 0.27 12.1 5.5 1.7 1 1 0 1 1 1 0 PPIC-type PPIASE domain ZapB PF06005.12 KXH34204.1 - 0.38 11.2 4.7 0.46 11.0 2.6 2.2 1 1 1 2 2 2 0 Cell division protein ZapB GAT PF03127.14 KXH34204.1 - 0.4 11.0 2.4 1.4 9.3 1.8 2.2 1 1 1 2 2 2 0 GAT domain CP12 PF02672.15 KXH34204.1 - 9.3 7.1 8.1 8.8 7.2 2.9 2.6 2 0 0 2 2 2 0 CP12 domain MFS_1 PF07690.16 KXH34205.1 - 5.2e-35 121.0 55.6 1e-28 100.3 32.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3450 PF11932.8 KXH34206.1 - 0.23 10.7 14.2 0.31 10.3 14.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF3316 PF11777.8 KXH34206.1 - 0.28 11.2 1.1 0.48 10.5 1.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3316) Macoilin PF09726.9 KXH34206.1 - 0.64 8.5 10.1 0.72 8.3 10.1 1.2 1 0 0 1 1 1 0 Macoilin family DUF853 PF05872.12 KXH34206.1 - 0.66 8.5 6.9 0.78 8.3 6.9 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) V_ATPase_I PF01496.19 KXH34206.1 - 0.68 7.8 4.7 0.78 7.6 4.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4407 PF14362.6 KXH34206.1 - 0.92 8.8 16.0 1.1 8.5 16.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF930 PF06059.12 KXH34206.1 - 1.3 9.6 5.2 0.99 10.0 3.2 1.7 1 1 0 1 1 1 0 Domain of Unknown Function (DUF930) RR_TM4-6 PF06459.12 KXH34206.1 - 2.1 8.1 8.9 2.4 7.9 8.9 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Ribosomal_L37 PF08561.10 KXH34206.1 - 3.4 8.2 20.8 0.28 11.7 0.7 2.1 1 1 1 2 2 2 0 Mitochondrial ribosomal protein L37 THOC7 PF05615.13 KXH34206.1 - 6.5 7.0 21.4 91 3.3 21.4 2.0 1 1 0 1 1 1 0 Tho complex subunit 7 FUSC PF04632.12 KXH34206.1 - 7.2 5.0 11.8 8.7 4.7 11.8 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family SHR3_chaperone PF08229.11 KXH34206.1 - 7.3 5.5 5.6 12 4.8 5.6 1.5 1 0 0 1 1 1 0 ER membrane protein SH3 DUF2834 PF11196.8 KXH34208.1 - 2.7 8.4 7.2 0.27 11.6 0.9 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2834) DivIC PF04977.15 KXH34210.1 - 0.0032 17.2 2.8 0.0032 17.2 2.8 1.8 2 0 0 2 2 2 1 Septum formation initiator DUF3450 PF11932.8 KXH34210.1 - 0.38 10.0 8.7 0.029 13.7 2.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) SlyX PF04102.12 KXH34210.1 - 0.72 10.5 3.9 0.4 11.3 0.7 2.1 2 0 0 2 2 2 0 SlyX DUF1840 PF08895.11 KXH34210.1 - 2.7 8.4 8.4 0.86 10.0 3.3 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF1840) Med9 PF07544.13 KXH34210.1 - 4.2 7.5 5.0 6 7.0 0.9 2.8 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 ABC_tran_CTD PF16326.5 KXH34210.1 - 4.5 7.6 6.5 1.8 8.9 1.1 2.4 2 0 0 2 2 2 0 ABC transporter C-terminal domain Fez1 PF06818.15 KXH34212.1 - 0.007 16.8 7.3 0.01 16.3 7.3 1.2 1 0 0 1 1 1 1 Fez1 Spc7 PF08317.11 KXH34212.1 - 0.0093 14.9 6.7 0.012 14.5 6.7 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein Uso1_p115_C PF04871.13 KXH34212.1 - 0.0094 16.3 11.8 0.01 16.2 10.7 1.7 1 1 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, C terminal region BLOC1_2 PF10046.9 KXH34212.1 - 0.013 15.8 5.0 0.023 15.0 3.7 2.0 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TMF_TATA_bd PF12325.8 KXH34212.1 - 0.034 14.4 8.3 0.063 13.5 8.3 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding MetOD2 PF18548.1 KXH34212.1 - 0.052 13.7 0.8 0.052 13.7 0.8 2.3 1 1 1 2 2 2 0 Metanogen output domain 2 GLE1 PF07817.13 KXH34212.1 - 0.061 12.5 0.6 0.082 12.1 0.6 1.3 1 0 0 1 1 1 0 GLE1-like protein NYD-SP28_assoc PF14775.6 KXH34212.1 - 0.079 13.1 1.7 0.15 12.2 1.7 1.5 1 0 0 1 1 1 0 Sperm tail C-terminal domain FliD_N PF02465.18 KXH34212.1 - 0.53 11.0 7.0 0.094 13.4 2.3 2.1 2 1 1 3 3 3 0 Flagellar hook-associated protein 2 N-terminus Prominin PF05478.11 KXH34212.1 - 0.58 8.0 3.1 0.71 7.8 3.1 1.1 1 0 0 1 1 1 0 Prominin V_ATPase_I PF01496.19 KXH34212.1 - 0.68 7.8 4.0 0.78 7.6 4.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Phlebovirus_NSM PF07246.11 KXH34212.1 - 0.78 9.1 9.6 1 8.7 9.4 1.3 1 1 0 1 1 1 0 Phlebovirus nonstructural protein NS-M Ntox15 PF15604.6 KXH34212.1 - 1.1 9.3 11.6 0.078 13.1 1.2 2.2 1 1 1 2 2 2 0 Novel toxin 15 Fzo_mitofusin PF04799.13 KXH34212.1 - 2.2 7.8 5.8 11 5.6 4.5 2.0 1 1 1 2 2 2 0 fzo-like conserved region DUF4407 PF14362.6 KXH34212.1 - 2.3 7.5 12.1 5.4 6.3 12.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) YabA PF06156.13 KXH34212.1 - 7.3 7.3 8.4 31 5.3 8.2 2.2 1 1 0 1 1 1 0 Initiation control protein YabA MIP PF00230.20 KXH34213.1 - 5.7e-48 163.6 15.0 7e-48 163.3 15.0 1.0 1 0 0 1 1 1 1 Major intrinsic protein Sec61_beta PF03911.16 KXH34213.1 - 0.06 13.4 1.0 14 5.8 0.0 2.9 2 0 0 2 2 2 0 Sec61beta family PI3K_P85_iSH2 PF16454.5 KXH34214.1 - 0.0049 16.5 3.8 0.0049 16.5 3.8 1.9 1 1 1 2 2 2 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain FlxA PF14282.6 KXH34214.1 - 0.0076 16.2 2.5 0.0076 16.2 2.5 1.9 1 1 1 2 2 2 1 FlxA-like protein DUF3450 PF11932.8 KXH34214.1 - 0.0081 15.5 0.3 0.015 14.6 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) FTA4 PF13093.6 KXH34214.1 - 0.026 14.4 4.8 0.026 14.4 1.2 2.0 1 1 1 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 ABC_tran_CTD PF16326.5 KXH34214.1 - 0.082 13.2 6.6 1.2 9.4 0.5 3.2 2 1 1 3 3 3 0 ABC transporter C-terminal domain Syntaxin-6_N PF09177.11 KXH34214.1 - 0.11 13.1 6.5 0.18 12.4 5.2 2.1 2 1 0 2 2 2 0 Syntaxin 6, N-terminal HSP70 PF00012.20 KXH34214.1 - 0.13 10.4 4.7 0.16 10.2 4.7 1.2 1 0 0 1 1 1 0 Hsp70 protein Fmp27_WPPW PF10359.9 KXH34214.1 - 0.17 10.7 11.1 0.15 10.9 10.1 1.4 1 1 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF4200 PF13863.6 KXH34214.1 - 0.51 10.7 15.9 0.55 10.6 5.8 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) CCDC-167 PF15188.6 KXH34214.1 - 0.63 10.4 11.2 0.1 13.0 2.2 2.6 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 Prominin PF05478.11 KXH34214.1 - 0.69 7.8 6.3 0.96 7.3 6.3 1.2 1 0 0 1 1 1 0 Prominin ADIP PF11559.8 KXH34214.1 - 0.76 9.9 13.4 0.087 12.9 4.7 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding RPW8 PF05659.11 KXH34214.1 - 0.77 9.4 9.1 0.17 11.5 4.4 2.1 1 1 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Spectrin PF00435.21 KXH34214.1 - 0.84 10.1 8.6 7.6 7.1 0.9 2.7 1 1 0 2 2 2 0 Spectrin repeat TMPIT PF07851.13 KXH34214.1 - 1.8 7.7 7.8 2.5 7.3 7.8 1.2 1 0 0 1 1 1 0 TMPIT-like protein LMBR1 PF04791.16 KXH34214.1 - 3.5 6.4 4.6 3.7 6.3 4.6 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein XhlA PF10779.9 KXH34214.1 - 5.1 7.4 15.4 1.2 9.4 4.0 3.1 2 1 2 4 4 4 0 Haemolysin XhlA APG6_N PF17675.1 KXH34214.1 - 5.3 7.6 13.8 19 5.8 13.8 1.8 1 1 0 1 1 1 0 Apg6 coiled-coil region Prefoldin PF02996.17 KXH34214.1 - 6 6.8 8.7 13 5.7 0.5 3.0 2 1 1 3 3 3 0 Prefoldin subunit SlyX PF04102.12 KXH34214.1 - 6.1 7.6 8.3 1.9 9.2 0.2 3.2 3 1 1 4 4 3 0 SlyX MTTB PF06253.11 KXH34215.1 - 0.063 11.2 5.5 0.099 10.6 5.5 1.3 1 1 0 1 1 1 0 Trimethylamine methyltransferase (MTTB) Ank_2 PF12796.7 KXH34217.1 - 8e-10 39.2 1.0 0.001 19.6 0.1 4.4 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXH34217.1 - 1.3e-07 32.0 0.2 0.28 11.8 0.0 4.4 4 1 0 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXH34217.1 - 2.2e-05 24.5 5.1 1.7 9.5 0.0 6.8 6 1 0 6 6 6 1 Ankyrin repeat Ank_5 PF13857.6 KXH34217.1 - 0.0012 19.1 2.9 1.2 9.5 0.0 4.6 5 0 0 5 5 5 1 Ankyrin repeats (many copies) F-box-like PF12937.7 KXH34217.1 - 1 9.3 3.2 3.6 7.6 0.1 2.9 3 0 0 3 3 3 0 F-box-like Zn_clus PF00172.18 KXH34218.1 - 8e-05 22.7 4.7 0.00016 21.7 4.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ank_5 PF13857.6 KXH34218.1 - 0.0022 18.3 0.2 0.72 10.3 0.0 3.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 KXH34218.1 - 0.0056 17.1 0.0 12 6.5 0.0 3.8 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.7 KXH34218.1 - 0.027 15.0 0.0 1.1 9.9 0.0 2.7 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXH34218.1 - 0.15 12.7 0.0 39 5.3 0.0 3.8 2 0 0 2 2 2 0 Ankyrin repeat MFS_1 PF07690.16 KXH34219.1 - 4.9e-23 81.6 24.5 1.8e-20 73.2 21.8 2.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Fib_alpha PF08702.10 KXH34220.1 - 0.074 13.2 3.6 0.16 12.2 3.6 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family FUSC PF04632.12 KXH34220.1 - 0.8 8.2 3.8 1.1 7.7 3.8 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Herpes_UL6 PF01763.16 KXH34220.1 - 3.4 6.1 5.5 4.9 5.5 5.5 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like HIP1_clath_bdg PF16515.5 KXH34220.1 - 5.2 7.7 13.2 18 6.0 13.2 1.8 1 1 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 p450 PF00067.22 KXH34242.1 - 3.7e-39 134.7 0.0 5.2e-39 134.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF998 PF06197.13 KXH34242.1 - 0.012 15.2 0.0 0.02 14.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF998) Solute_trans_a PF03619.16 KXH34243.1 - 1.6e-73 247.5 13.1 2.1e-73 247.1 13.1 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha ERGIC_N PF13850.6 KXH34243.1 - 0.017 15.4 1.0 0.056 13.8 0.2 2.2 2 0 0 2 2 2 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) PsbX PF06596.11 KXH34243.1 - 0.067 13.2 1.1 0.15 12.1 1.1 1.6 1 0 0 1 1 1 0 Photosystem II reaction centre X protein (PsbX) GWT1 PF06423.12 KXH34243.1 - 0.21 11.7 4.7 0.57 10.3 0.2 2.5 2 1 0 2 2 2 0 GWT1 L_HMGIC_fpl PF10242.9 KXH34243.1 - 3.7 7.7 9.1 3 8.0 2.2 2.3 2 0 0 2 2 2 0 Lipoma HMGIC fusion partner-like protein Pam16 PF03656.13 KXH34244.1 - 3.7e-33 114.2 0.2 4.5e-33 114.0 0.2 1.0 1 0 0 1 1 1 1 Pam16 cwf21 PF08312.12 KXH34244.1 - 0.33 11.2 2.6 0.57 10.4 2.6 1.3 1 0 0 1 1 1 0 cwf21 domain Beta_helix PF13229.6 KXH34245.1 - 7.5e-11 42.1 18.6 9.6e-10 38.5 16.8 2.5 2 1 1 3 3 3 2 Right handed beta helix region Chondroitinas_B PF14592.6 KXH34245.1 - 3.8e-07 29.3 0.3 1e-06 27.9 0.0 1.7 2 0 0 2 2 2 1 Chondroitinase B DUF1565 PF07602.11 KXH34245.1 - 0.0014 18.0 0.2 0.0014 18.0 0.2 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF1565) Yip1 PF04893.17 KXH34246.1 - 0.00054 19.7 16.9 0.0058 16.4 7.1 2.8 3 1 1 4 4 4 2 Yip1 domain RCC1 PF00415.18 KXH34247.1 - 6.5e-61 202.8 0.3 4.6e-10 40.0 0.0 7.6 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KXH34247.1 - 2e-35 119.8 26.9 1.6e-07 31.0 1.0 6.6 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat DUF966 PF06136.13 KXH34247.1 - 2.1 8.0 19.7 3.2 7.4 19.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF966) APH PF01636.23 KXH34250.1 - 0.00034 20.6 0.0 0.0007 19.6 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KXH34250.1 - 0.065 12.8 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase GMC_oxred_N PF00732.19 KXH34251.1 - 1.1e-59 202.2 0.0 1.5e-59 201.9 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXH34251.1 - 4.6e-28 98.6 0.0 7.7e-28 97.8 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KXH34251.1 - 1.3e-05 24.5 0.0 0.025 13.7 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 KXH34251.1 - 0.0012 18.5 1.2 0.01 15.4 1.2 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXH34251.1 - 0.0014 18.8 0.0 0.0045 17.2 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KXH34251.1 - 0.0027 17.0 0.0 0.29 10.3 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXH34251.1 - 0.0053 16.0 0.0 0.0098 15.2 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 KXH34251.1 - 0.015 14.6 0.1 0.4 9.9 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXH34251.1 - 0.065 11.9 0.0 0.2 10.3 0.0 1.7 2 0 0 2 2 2 0 HI0933-like protein Lycopene_cycl PF05834.12 KXH34251.1 - 0.069 12.2 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein AA_permease_2 PF13520.6 KXH34252.1 - 2.7e-59 201.1 50.0 3.3e-59 200.8 50.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXH34252.1 - 2.8e-27 95.5 37.4 3.9e-27 95.0 37.4 1.1 1 0 0 1 1 1 1 Amino acid permease TB2_DP1_HVA22 PF03134.19 KXH34253.1 - 5.4e-27 93.5 8.7 8.4e-27 92.9 8.7 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Mgm101p PF06420.12 KXH34254.1 - 5.8e-85 283.0 0.0 7.7e-85 282.6 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 Ndc1_Nup PF09531.10 KXH34254.1 - 0.00063 18.6 3.2 0.00063 18.6 3.2 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Suf PF05843.14 KXH34254.1 - 0.014 15.4 8.9 0.019 14.9 8.9 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) TFIIA PF03153.13 KXH34254.1 - 1.9 8.4 17.1 2.6 7.9 17.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CHCH PF06747.13 KXH34255.1 - 0.0055 16.8 8.6 0.01 15.9 8.6 1.5 1 0 0 1 1 1 1 CHCH domain Cmc1 PF08583.10 KXH34255.1 - 0.04 13.9 3.9 0.13 12.3 3.9 1.8 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like COX17 PF05051.13 KXH34255.1 - 0.043 14.2 2.3 0.066 13.6 2.3 1.3 1 0 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) GT-D PF08759.11 KXH34255.1 - 0.08 12.6 0.2 0.085 12.5 0.2 1.0 1 0 0 1 1 1 0 Glycosyltransferase GT-D fold CX9C PF16860.5 KXH34255.1 - 0.5 10.4 5.2 1.6 8.8 1.3 2.3 1 1 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, BPL_N PF09825.9 KXH34256.1 - 3e-142 474.2 0.0 3.7e-142 473.9 0.0 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.19 KXH34256.1 - 5.5e-20 71.6 0.0 9.2e-20 70.9 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.17 KXH34256.1 - 0.034 14.0 0.0 0.069 13.1 0.0 1.6 1 0 0 1 1 1 0 Biotin protein ligase C terminal domain GST_N PF02798.20 KXH34257.1 - 8.2e-08 32.5 0.0 2.2e-07 31.1 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KXH34257.1 - 2.3e-06 27.9 0.0 5e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KXH34257.1 - 3.3e-05 24.1 0.1 7.6e-05 22.9 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KXH34257.1 - 3.7e-05 23.7 0.0 9.2e-05 22.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KXH34257.1 - 0.002 18.3 0.0 0.0058 16.8 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KXH34257.1 - 0.023 14.9 0.0 0.068 13.4 0.0 1.8 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Polyketide_cyc2 PF10604.9 KXH34259.1 - 0.00083 19.6 0.0 0.002 18.4 0.0 1.7 2 0 0 2 2 2 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 KXH34259.1 - 0.053 13.7 0.0 0.097 12.9 0.0 1.5 1 0 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport RAP80_UIM PF18282.1 KXH34260.1 - 0.071 12.9 0.0 0.24 11.2 0.0 1.8 1 0 0 1 1 1 0 RAP80 N-terminal ubiquitin interaction motif WSC PF01822.19 KXH34261.1 - 9.4e-70 230.8 60.1 7.5e-19 67.7 8.4 4.9 4 0 0 4 4 4 4 WSC domain Pec_lyase_C PF00544.19 KXH34262.1 - 4.8e-19 68.8 14.3 9.1e-18 64.6 14.3 2.4 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 KXH34262.1 - 2e-05 24.5 18.5 0.0006 19.7 18.5 2.3 1 1 0 1 1 1 1 Right handed beta helix region FAD_binding_3 PF01494.19 KXH34262.1 - 0.093 12.0 2.2 1.6 7.9 0.5 2.1 1 1 0 2 2 2 0 FAD binding domain CBM-like PF14683.6 KXH34263.1 - 9.7e-40 136.1 1.2 1.3e-38 132.5 0.4 2.5 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.6 KXH34263.1 - 4.1e-11 42.5 1.4 1.8e-10 40.5 1.4 2.2 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.6 KXH34263.1 - 1e-08 35.3 2.3 1e-08 35.3 2.3 3.1 4 0 0 4 4 4 1 Carboxypeptidase regulatory-like domain SdrD_B PF17210.3 KXH34263.1 - 0.014 15.6 2.9 0.032 14.5 1.3 2.3 2 0 0 2 2 2 0 SdrD B-like domain CarbopepD_reg_2 PF13715.6 KXH34263.1 - 0.029 14.4 3.2 0.3 11.1 2.3 2.9 2 1 0 2 2 2 0 CarboxypepD_reg-like domain AAA PF00004.29 KXH34264.1 - 1e-12 48.7 0.3 5.8e-12 46.2 0.3 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KXH34264.1 - 0.0054 17.1 1.2 0.02 15.3 1.2 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KXH34264.1 - 0.045 14.0 1.9 1.2 9.4 0.6 2.6 2 0 0 2 2 2 0 AAA domain MRP-S26 PF14943.6 KXH34264.1 - 0.061 13.2 4.6 0.028 14.3 1.7 1.9 2 0 0 2 2 2 0 Mitochondrial ribosome subunit S26 Tau95 PF09734.9 KXH34264.1 - 0.12 13.1 0.7 0.33 11.7 0.3 1.9 2 0 0 2 2 2 0 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain CDRN PF05174.12 KXH34265.1 - 0.01 15.5 1.0 3.6 7.3 0.0 3.0 2 0 0 2 2 2 0 Cysteine-rich D. radiodurans N terminus MFS_1 PF07690.16 KXH34266.1 - 3.1e-35 121.7 24.3 4.3e-35 121.3 24.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans PF04082.18 KXH34267.1 - 2.5e-19 69.4 0.0 9.8e-19 67.4 0.0 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH34267.1 - 3.7e-08 33.3 10.4 6.2e-08 32.6 10.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Hydantoinase_B PF02538.14 KXH34268.1 - 2.8e-210 699.1 0.7 3.7e-210 698.7 0.7 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 KXH34268.1 - 4.2e-103 344.6 0.5 1e-102 343.3 0.1 1.8 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 KXH34268.1 - 2.4e-59 200.0 2.7 1.7e-58 197.3 0.1 2.4 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region DHDPS PF00701.22 KXH34269.1 - 1.9e-44 151.5 0.0 2.2e-44 151.3 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family LrgB PF04172.16 KXH34270.1 - 0.098 12.2 0.3 0.13 11.8 0.3 1.3 1 0 0 1 1 1 0 LrgB-like family DUF4646 PF15496.6 KXH34271.1 - 0.00056 20.5 1.2 0.59 10.8 0.1 2.3 1 1 1 2 2 2 2 Domain of unknown function (DUF4646) CorA PF01544.18 KXH34272.1 - 2.1e-06 27.3 0.0 3.2e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF2207 PF09972.9 KXH34272.1 - 0.02 13.7 0.2 0.032 13.0 0.2 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) GMC_oxred_N PF00732.19 KXH34273.1 - 5.7e-30 104.7 0.2 4.5e-29 101.7 0.3 2.2 2 1 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXH34273.1 - 1.2e-29 103.6 0.0 2.4e-29 102.7 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KXH34273.1 - 0.00098 18.3 0.3 0.016 14.3 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 KXH34273.1 - 0.0036 16.6 0.0 0.021 14.0 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXH34273.1 - 0.0049 16.2 0.0 0.66 9.2 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXH34273.1 - 0.13 12.5 0.1 0.32 11.3 0.1 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain RRM_1 PF00076.22 KXH34274.1 - 2.4e-08 33.7 0.1 4.3e-08 32.9 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KXH34274.1 - 9.6e-05 22.3 0.0 0.00017 21.5 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 KXH34274.1 - 0.005 16.7 0.1 0.0088 15.9 0.1 1.3 1 0 0 1 1 1 1 Occluded RNA-recognition motif RRM_3 PF08777.11 KXH34274.1 - 0.082 13.0 0.1 0.16 12.0 0.1 1.4 1 0 0 1 1 1 0 RNA binding motif DUF3659 PF12396.8 KXH34276.1 - 1.7e-165 537.1 99.7 1.6e-21 76.0 2.3 10.3 10 0 0 10 10 10 9 Protein of unknown function (DUF3659) GCV_T_C PF08669.11 KXH34276.1 - 0.00023 21.0 10.1 5.6 7.0 0.0 7.2 5 1 3 8 8 8 2 Glycine cleavage T-protein C-terminal barrel domain DUF1917 PF08939.10 KXH34276.1 - 0.0052 16.7 1.5 0.015 15.2 1.5 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1917) DUF3659 PF12396.8 KXH34277.1 - 9.1e-18 63.9 4.9 5.5e-13 48.6 0.9 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3659) DUF719 PF05334.13 KXH34278.1 - 0.0043 17.3 0.7 0.0051 17.0 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF719) LPD3 PF18798.1 KXH34279.1 - 0.14 12.4 0.0 0.21 11.9 0.0 1.2 1 0 0 1 1 1 0 Large polyvalent protein-associated domain 3 DUF2046 PF09755.9 KXH34281.1 - 0.0029 16.9 1.7 0.041 13.1 0.1 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein H4 (DUF2046) CASP_C PF08172.12 KXH34281.1 - 0.01 15.2 6.4 0.7 9.2 0.1 2.3 2 0 0 2 2 2 2 CASP C terminal DivIC PF04977.15 KXH34281.1 - 0.02 14.6 0.7 0.02 14.6 0.7 1.7 2 0 0 2 2 2 0 Septum formation initiator NUDE_C PF04880.13 KXH34281.1 - 0.028 14.9 0.5 0.028 14.9 0.5 3.7 3 1 0 3 3 3 0 NUDE protein, C-terminal conserved region DUF3138 PF11336.8 KXH34281.1 - 6.5 5.2 11.1 0.38 9.3 1.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) Phage_TAC_6 PF09550.10 KXH34282.1 - 0.029 14.8 3.4 0.063 13.7 3.4 1.5 1 0 0 1 1 1 0 Phage tail assembly chaperone protein, TAC FMO-like PF00743.19 KXH34283.1 - 1.3e-16 60.1 1.7 7.7e-15 54.3 0.1 2.3 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KXH34283.1 - 2e-12 47.0 0.0 1.1e-06 28.1 0.0 2.6 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXH34283.1 - 4.6e-09 35.9 0.1 2.1e-08 33.7 0.0 1.9 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KXH34283.1 - 9.9e-08 31.6 0.0 1.4e-06 27.8 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXH34283.1 - 0.063 13.5 3.0 0.21 11.8 0.0 3.1 3 1 0 3 3 3 0 NAD(P)-binding Rossmann-like domain CCP_MauG PF03150.14 KXH34283.1 - 0.16 12.6 0.0 0.31 11.7 0.0 1.4 1 0 0 1 1 1 0 Di-haem cytochrome c peroxidase Beta-lactamase PF00144.24 KXH34284.1 - 5.4e-42 144.2 0.0 1.4e-41 142.8 0.0 1.6 1 1 0 1 1 1 1 Beta-lactamase Zn_clus PF00172.18 KXH34285.1 - 5.6e-05 23.2 16.4 0.00064 19.8 16.4 2.4 1 1 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FmdA_AmdA PF03069.15 KXH34286.1 - 1.3e-53 182.3 0.0 3.9e-35 121.4 0.0 2.1 1 1 1 2 2 2 2 Acetamidase/Formamidase family DUF3433 PF11915.8 KXH34287.1 - 3.2e-24 85.2 22.5 4.4e-19 68.7 4.7 3.8 4 0 0 4 4 4 2 Protein of unknown function (DUF3433) SnoaL_2 PF12680.7 KXH34288.1 - 2.1e-10 41.1 0.3 3.7e-10 40.3 0.3 1.3 1 1 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 KXH34288.1 - 8.9e-05 22.3 0.2 0.00036 20.3 0.2 1.8 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase DUF4440 PF14534.6 KXH34288.1 - 0.001 19.5 0.1 0.0015 18.9 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_3 PF13474.6 KXH34288.1 - 0.0028 17.9 0.2 0.0096 16.2 0.1 1.9 1 1 1 2 2 2 1 SnoaL-like domain GMC_oxred_N PF00732.19 KXH34290.1 - 8.8e-29 100.8 0.0 1.6e-28 100.0 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXH34290.1 - 3.7e-21 76.1 0.7 8.4e-21 75.0 0.7 1.6 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 KXH34290.1 - 2.2e-06 27.1 0.7 8.8e-05 21.9 0.1 3.3 3 1 1 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KXH34290.1 - 1.1e-05 25.0 0.0 9e-05 22.0 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KXH34290.1 - 3.9e-05 22.5 1.4 0.00019 20.3 0.1 2.5 3 0 0 3 3 3 1 HI0933-like protein NAD_binding_8 PF13450.6 KXH34290.1 - 0.00016 21.9 0.1 0.00063 19.9 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KXH34290.1 - 0.00064 18.9 0.5 0.00064 18.9 0.5 2.1 3 0 0 3 3 3 1 FAD binding domain GIDA PF01134.22 KXH34290.1 - 0.0028 16.8 0.1 0.0048 16.0 0.1 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A DAO PF01266.24 KXH34290.1 - 0.012 15.3 3.7 0.12 11.9 3.7 2.2 1 1 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KXH34290.1 - 0.023 13.9 0.0 0.04 13.1 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 KXH34290.1 - 0.033 13.3 0.0 0.049 12.7 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox PF00070.27 KXH34290.1 - 0.039 14.5 0.3 0.15 12.7 0.2 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXH34290.1 - 0.052 12.8 0.1 0.14 11.4 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KXH34290.1 - 0.097 11.5 0.1 0.15 10.9 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Ank_2 PF12796.7 KXH34291.1 - 1.1e-25 90.0 1.4 3.5e-08 33.9 0.1 5.2 3 1 3 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXH34291.1 - 5.2e-22 77.9 7.4 8.8e-07 29.4 0.4 6.2 3 1 4 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXH34291.1 - 1.1e-17 62.3 7.2 0.18 12.5 0.0 8.6 9 0 0 9 9 9 6 Ankyrin repeat Ank_5 PF13857.6 KXH34291.1 - 2.7e-17 62.6 6.2 0.0001 22.5 0.0 6.4 2 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 KXH34291.1 - 9.2e-15 54.3 9.2 0.045 14.2 0.1 8.1 8 0 0 8 8 8 4 Ankyrin repeat HET PF06985.11 KXH34291.1 - 2.2e-14 54.0 1.5 4.6e-11 43.3 0.0 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) DUF892 PF05974.12 KXH34292.1 - 0.012 15.6 0.1 0.017 15.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF892) HpcH_HpaI PF03328.14 KXH34293.1 - 5.5e-21 74.7 0.0 1e-20 73.8 0.0 1.4 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family bZIP_2 PF07716.15 KXH34294.1 - 0.00026 21.0 2.2 0.00026 21.0 2.2 2.3 3 0 0 3 3 3 1 Basic region leucine zipper bZIP_1 PF00170.21 KXH34294.1 - 0.00028 20.9 5.1 0.00028 20.9 5.1 2.2 1 1 0 1 1 1 1 bZIP transcription factor YscO PF07321.12 KXH34294.1 - 0.003 17.5 8.6 0.005 16.8 8.6 1.3 1 0 0 1 1 1 1 Type III secretion protein YscO DUF1484 PF07363.11 KXH34294.1 - 0.96 10.5 6.3 0.51 11.4 1.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1484) SARA PF11409.8 KXH34295.1 - 0.024 14.8 1.2 0.082 13.1 1.2 2.0 1 0 0 1 1 1 0 Smad anchor for receptor activation (SARA) FUSC PF04632.12 KXH34295.1 - 0.21 10.1 2.8 0.29 9.6 2.8 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family CENP-O PF09496.10 KXH34296.1 - 0.086 12.8 4.2 0.12 12.4 4.2 1.2 1 0 0 1 1 1 0 Cenp-O kinetochore centromere component NinG PF05766.12 KXH34296.1 - 0.18 11.7 5.1 0.26 11.2 5.1 1.3 1 0 0 1 1 1 0 Bacteriophage Lambda NinG protein zf-C2H2_4 PF13894.6 KXH34297.1 - 1 10.4 2.3 2 9.5 2.3 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_4 PF13894.6 KXH34299.1 - 0.1 13.5 0.1 0.17 12.8 0.1 1.4 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KXH34300.1 - 0.015 15.7 1.4 0.026 15.0 1.4 1.4 1 0 0 1 1 1 0 Zinc finger, C2H2 type Glyco_hydr_30_2 PF14587.6 KXH34302.1 - 7.5e-17 62.0 11.7 3.2e-16 59.9 8.7 2.7 2 1 1 3 3 3 1 O-Glycosyl hydrolase family 30 Glyco_hydro_59 PF02057.15 KXH34302.1 - 1.1e-09 37.9 5.3 2.4e-09 36.9 4.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 59 Rtt106 PF08512.12 KXH34304.1 - 0.073 13.5 0.2 0.28 11.6 0.1 2.0 2 1 0 2 2 2 0 Histone chaperone Rttp106-like Inhibitor_I36 PF03995.13 KXH34305.1 - 0.033 14.1 0.3 0.076 12.9 0.3 1.6 1 0 0 1 1 1 0 Peptidase inhibitor family I36 COesterase PF00135.28 KXH34307.1 - 2.9e-89 300.3 0.1 3.8e-89 299.9 0.1 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXH34307.1 - 3.1e-05 23.9 0.1 0.0001 22.2 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KXH34307.1 - 0.002 17.6 0.0 0.0037 16.8 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF5050 PF16472.5 KXH34309.1 - 0.04 13.2 0.2 3.9 6.6 0.0 2.3 1 1 2 3 3 3 0 Domain of unknown function (DUF5050) PNTB_4TM PF12769.7 KXH34310.1 - 0.11 13.0 0.1 0.17 12.4 0.1 1.3 1 0 0 1 1 1 0 4TM region of pyridine nucleotide transhydrogenase, mitoch Neur_chan_memb PF02932.16 KXH34311.1 - 0.31 11.1 13.0 1.2 9.1 6.5 2.5 1 1 1 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Ank_2 PF12796.7 KXH34312.1 - 2.8e-32 111.1 0.5 4.7e-07 30.3 0.1 6.7 2 2 6 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXH34312.1 - 1.6e-27 95.5 6.0 0.00039 20.9 0.1 8.3 4 2 4 8 8 8 6 Ankyrin repeats (many copies) NACHT_N PF17100.5 KXH34312.1 - 1.2e-23 84.1 0.0 2.8e-23 82.9 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of NWD NACHT-NTPase Ank_5 PF13857.6 KXH34312.1 - 4.8e-22 77.7 12.3 1.2e-08 35.1 0.2 7.2 4 3 3 7 7 7 5 Ankyrin repeats (many copies) Ank PF00023.30 KXH34312.1 - 8.3e-13 48.2 10.4 0.074 13.5 0.0 9.0 10 0 0 10 10 9 4 Ankyrin repeat Ank_3 PF13606.6 KXH34312.1 - 1.8e-11 43.2 4.6 0.017 15.6 0.0 8.5 10 0 0 10 10 8 2 Ankyrin repeat NACHT PF05729.12 KXH34312.1 - 2.1e-07 31.0 0.1 5e-07 29.8 0.1 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KXH34312.1 - 0.0029 18.0 0.0 0.018 15.4 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain Cas_Csy2 PF09614.10 KXH34312.1 - 0.09 12.1 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy2) GSG-1 PF07803.11 KXH34312.1 - 0.14 12.0 0.0 0.34 10.8 0.0 1.6 1 0 0 1 1 1 0 GSG1-like protein AAA_18 PF13238.6 KXH34312.1 - 0.36 11.4 1.9 4.8 7.7 0.1 3.2 3 1 0 3 3 2 0 AAA domain Vps62 PF06101.11 KXH34313.1 - 3.3e-05 22.4 3.2 0.00017 20.1 0.1 2.5 3 0 0 3 3 3 2 Vacuolar protein sorting-associated protein 62 Sugar_tr PF00083.24 KXH34314.1 - 5.6e-92 308.9 22.6 7e-92 308.6 22.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH34314.1 - 1.9e-12 46.8 42.7 2.2e-09 36.7 16.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 KXH34315.1 - 2.4e-30 105.7 25.4 3.7e-30 105.1 25.4 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily PEMT PF04191.13 KXH34315.1 - 0.26 11.7 4.1 3 8.3 0.3 3.4 1 1 2 3 3 3 0 Phospholipid methyltransferase Saf_2TM PF18303.1 KXH34315.1 - 4.1 7.0 12.1 0.12 12.0 1.3 3.1 4 0 0 4 4 4 0 SAVED-fused 2TM effector domain MAPEG PF01124.18 KXH34315.1 - 5 7.0 8.8 0.14 12.0 0.6 2.7 4 0 0 4 4 4 0 MAPEG family DbpA PF03880.15 KXH34317.1 - 0.0086 16.0 0.0 0.017 15.1 0.0 1.5 1 0 0 1 1 1 1 DbpA RNA binding domain RRM_1 PF00076.22 KXH34317.1 - 0.11 12.3 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HsbA PF12296.8 KXH34319.1 - 3.4e-23 82.3 10.5 3.4e-23 82.3 10.5 1.7 2 0 0 2 2 2 1 Hydrophobic surface binding protein A adh_short PF00106.25 KXH34593.1 - 1e-10 41.4 0.0 0.004 16.6 0.0 3.1 2 1 1 3 3 3 3 short chain dehydrogenase adh_short_C2 PF13561.6 KXH34593.1 - 1.2e-09 38.0 0.0 2.3e-05 24.1 0.0 2.4 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH34593.1 - 0.00072 19.5 0.0 0.0015 18.4 0.0 1.5 1 0 0 1 1 1 1 KR domain mono-CXXC PF15626.6 KXH34593.1 - 0.15 12.4 0.5 0.15 12.4 0.5 2.0 2 0 0 2 2 2 0 single CXXC unit NAD_binding_10 PF13460.6 KXH34593.1 - 0.16 11.8 0.8 14 5.5 0.0 2.2 1 1 1 2 2 2 0 NAD(P)H-binding fn3_2 PF16893.5 KXH34594.1 - 2.2e-38 130.3 0.1 3.5e-38 129.6 0.1 1.3 1 0 0 1 1 1 1 Fibronectin type III domain CHS5_N PF16892.5 KXH34594.1 - 1.9e-23 82.1 0.8 3.3e-23 81.4 0.8 1.4 1 0 0 1 1 1 1 Chitin biosynthesis protein CHS5 N-terminus PTCB-BRCT PF12738.7 KXH34594.1 - 3.7e-12 46.0 0.0 6.9e-12 45.1 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 KXH34594.1 - 1.2e-10 41.6 0.0 2.3e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KXH34594.1 - 6e-06 26.6 0.0 2e-05 24.9 0.0 1.9 1 1 1 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain fn3 PF00041.21 KXH34594.1 - 0.00063 20.0 0.0 0.0018 18.6 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III domain DUF3006 PF11213.8 KXH34594.1 - 0.0075 16.5 0.5 0.024 14.8 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3006) eIF-1a PF01176.19 KXH34596.1 - 1.1e-21 76.3 0.1 1.6e-21 75.9 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 WH1 PF00568.23 KXH34597.1 - 1.8e-25 89.0 0.1 2.4e-25 88.6 0.1 1.2 1 0 0 1 1 1 1 WH1 domain WH2 PF02205.20 KXH34597.1 - 0.00048 19.9 0.5 0.0014 18.4 0.5 1.8 1 0 0 1 1 1 1 WH2 motif ERCC4 PF02732.15 KXH34599.1 - 2e-18 67.1 0.0 6.9e-18 65.3 0.0 1.9 2 0 0 2 2 2 1 ERCC4 domain Kelch_5 PF13854.6 KXH34601.1 - 1.7e-12 47.0 7.0 6.2e-05 22.9 0.0 5.7 7 0 0 7 7 7 3 Kelch motif Kelch_2 PF07646.15 KXH34601.1 - 6.2e-05 22.8 0.9 2.2 8.4 0.0 4.8 4 1 0 4 4 4 2 Kelch motif SKG6 PF08693.10 KXH34601.1 - 0.0038 16.6 0.5 0.0081 15.5 0.5 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Alpha_GJ PF03229.13 KXH34601.1 - 0.0041 17.7 0.6 0.0041 17.7 0.6 2.0 2 0 0 2 2 2 1 Alphavirus glycoprotein J Herpes_gE PF02480.16 KXH34601.1 - 0.0066 15.3 0.0 0.01 14.6 0.0 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E Kelch_4 PF13418.6 KXH34601.1 - 0.0069 16.4 8.0 0.025 14.6 0.5 4.5 4 2 0 4 4 4 1 Galactose oxidase, central domain Kelch_6 PF13964.6 KXH34601.1 - 0.029 14.7 0.4 6.5 7.2 0.0 4.1 3 0 0 3 3 3 0 Kelch motif Kelch_1 PF01344.25 KXH34601.1 - 0.1 12.2 1.2 17 5.1 0.2 4.0 4 0 0 4 4 4 0 Kelch motif Gram_pos_anchor PF00746.21 KXH34601.1 - 0.21 11.5 1.6 0.48 10.4 1.6 1.6 1 0 0 1 1 1 0 LPXTG cell wall anchor motif ZapB PF06005.12 KXH34602.1 - 0.0011 19.3 0.8 0.0011 19.3 0.8 1.8 1 1 1 2 2 2 1 Cell division protein ZapB DUF4407 PF14362.6 KXH34602.1 - 0.0013 18.1 0.6 0.0015 18.0 0.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) DUF2205 PF10224.9 KXH34602.1 - 0.0057 16.6 1.4 0.0092 16.0 1.4 1.4 1 0 0 1 1 1 1 Short coiled-coil protein bZIP_1 PF00170.21 KXH34602.1 - 0.015 15.4 0.1 0.033 14.3 0.1 1.6 1 0 0 1 1 1 0 bZIP transcription factor KASH_CCD PF14662.6 KXH34602.1 - 0.021 14.7 3.3 0.029 14.2 3.3 1.2 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH NRBF2 PF08961.10 KXH34602.1 - 0.033 13.8 0.6 0.05 13.2 0.6 1.4 1 0 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator Spc7 PF08317.11 KXH34602.1 - 0.035 13.0 3.4 0.053 12.4 3.4 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein TSC22 PF01166.18 KXH34602.1 - 0.035 14.4 0.1 0.069 13.5 0.1 1.5 1 0 0 1 1 1 0 TSC-22/dip/bun family Prominin PF05478.11 KXH34602.1 - 0.045 11.7 0.4 0.052 11.5 0.4 1.1 1 0 0 1 1 1 0 Prominin DUF3972 PF13118.6 KXH34602.1 - 0.047 14.1 0.4 0.12 12.9 0.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3972) UPF0242 PF06785.11 KXH34602.1 - 0.058 13.5 1.5 0.077 13.1 1.5 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus THOC7 PF05615.13 KXH34602.1 - 0.069 13.4 2.8 0.15 12.4 2.8 1.5 1 1 0 1 1 1 0 Tho complex subunit 7 Troponin PF00992.20 KXH34602.1 - 0.08 13.2 3.1 0.11 12.8 3.1 1.2 1 0 0 1 1 1 0 Troponin DUF3251 PF11622.8 KXH34602.1 - 0.089 12.4 0.7 5 6.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3251) DUF16 PF01519.16 KXH34602.1 - 0.17 12.4 1.0 0.25 11.8 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF16 DUF5082 PF16888.5 KXH34602.1 - 0.34 11.2 3.9 0.59 10.4 1.8 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) DUF5595 PF18077.1 KXH34602.1 - 0.35 11.0 2.2 0.4 10.8 1.2 1.8 2 0 0 2 2 1 0 Domain of unknown function (DUF5595) Ifi-6-16 PF06140.13 KXH34603.1 - 2.1e-08 33.9 26.6 4.7e-08 32.8 26.6 1.6 1 1 0 1 1 1 1 Interferon-induced 6-16 family PLN_propep PF16485.5 KXH34604.1 - 6.4e-06 25.8 0.0 9.6e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 Protealysin propeptide Acyl_transf_3 PF01757.22 KXH34605.1 - 1.1e-34 120.0 26.2 4.1e-34 118.2 26.2 1.7 1 1 0 1 1 1 1 Acyltransferase family DUF418 PF04235.12 KXH34605.1 - 8.8e-05 22.5 5.2 8.8e-05 22.5 5.2 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF418) Peptidase_C69 PF03577.15 KXH34606.1 - 2.5e-22 79.4 0.1 3.8e-22 78.8 0.1 1.2 1 0 0 1 1 1 1 Peptidase family C69 Rpp20 PF12328.8 KXH34607.1 - 1.3e-26 93.2 0.0 1.9e-26 92.6 0.0 1.2 1 0 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.21 KXH34607.1 - 6.3e-11 41.9 0.0 9.2e-11 41.4 0.0 1.3 1 0 0 1 1 1 1 Alba Rogdi_lz PF10259.9 KXH34608.1 - 1e-92 310.4 0.1 1.1e-92 310.3 0.1 1.0 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein NIPSNAP PF07978.13 KXH34609.1 - 2.8e-41 139.9 0.6 8.3e-30 103.0 0.1 2.5 2 0 0 2 2 2 2 NIPSNAP Uds1 PF15456.6 KXH34609.1 - 0.029 14.5 1.2 0.057 13.6 1.2 1.5 1 0 0 1 1 1 0 Up-regulated During Septation SR-25 PF10500.9 KXH34609.1 - 9.9 5.7 14.2 16 5.0 14.2 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein ATP-synt_J PF04911.12 KXH34610.1 - 1e-27 95.4 0.7 1.2e-27 95.3 0.7 1.0 1 0 0 1 1 1 1 ATP synthase j chain FSH1 PF03959.13 KXH34611.1 - 5.1e-60 202.8 0.0 6.6e-60 202.4 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 KXH34611.1 - 0.01 16.4 3.9 0.042 14.4 3.9 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase family Esterase_phd PF10503.9 KXH34611.1 - 0.013 15.0 0.3 0.93 8.9 0.6 2.5 2 1 0 2 2 2 0 Esterase PHB depolymerase Abhydrolase_1 PF00561.20 KXH34611.1 - 0.02 14.6 0.1 0.31 10.6 0.1 2.3 2 1 1 3 3 3 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXH34611.1 - 0.028 13.7 0.1 0.26 10.5 0.0 2.4 3 1 0 3 3 3 0 Serine aminopeptidase, S33 DLH PF01738.18 KXH34611.1 - 0.036 13.6 0.0 5 6.6 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family Palm_thioest PF02089.15 KXH34611.1 - 0.11 12.3 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Abhydrolase_2 PF02230.16 KXH34611.1 - 0.13 12.0 0.0 31 4.3 0.1 2.9 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase PCI PF01399.27 KXH34612.1 - 3.1e-21 75.8 0.1 1e-20 74.2 0.1 1.9 1 0 0 1 1 1 1 PCI domain RPN5_C PF18098.1 KXH34612.1 - 2.1e-15 56.5 4.2 5.5e-15 55.2 4.2 1.8 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN5 C-terminal domain AltA1 PF16541.5 KXH34613.1 - 4.9e-14 53.1 0.0 6.9e-14 52.6 0.0 1.1 1 0 0 1 1 1 1 Alternaria alternata allergen 1 Glyco_hydr_30_2 PF14587.6 KXH34614.1 - 3.9e-14 53.0 2.2 8.8e-14 51.9 0.3 2.2 1 1 0 2 2 2 1 O-Glycosyl hydrolase family 30 Glyco_hydro_30C PF17189.4 KXH34614.1 - 1e-10 41.7 4.3 2.6e-10 40.3 4.3 1.8 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain Glyco_hydro_59 PF02057.15 KXH34614.1 - 8.5e-09 35.0 0.1 1.2e-08 34.6 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 Glyco_hydro_30 PF02055.16 KXH34614.1 - 2.3e-07 30.1 0.3 3.7e-07 29.4 0.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_61 PF03443.14 KXH34615.1 - 3.6e-41 141.4 0.0 5.6e-41 140.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 MFS_1 PF07690.16 KXH34616.1 - 1e-31 110.1 25.8 1e-31 110.1 25.8 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF3390 PF11870.8 KXH34616.1 - 0.055 13.8 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3390) DUF3784 PF12650.7 KXH34616.1 - 0.11 12.7 5.3 27 5.0 0.1 4.3 4 0 0 4 4 4 0 Domain of unknown function (DUF3784) DUF4519 PF15012.6 KXH34616.1 - 0.24 11.6 0.8 0.93 9.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) FMN_dh PF01070.18 KXH34617.1 - 1.1e-112 376.5 0.0 1.4e-112 376.2 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 KXH34617.1 - 2.3e-18 66.1 0.0 4.2e-18 65.2 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 KXH34617.1 - 4.7e-08 32.6 0.0 7e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 KXH34617.1 - 4.4e-05 23.1 0.0 6.2e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Glutamate synthase central domain IMPDH PF00478.25 KXH34617.1 - 4.8e-05 22.5 0.6 0.0002 20.5 0.3 1.8 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.14 KXH34617.1 - 0.0002 20.8 0.1 0.12 11.7 0.0 2.2 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG NMO PF03060.15 KXH34617.1 - 0.00079 18.9 0.3 0.0013 18.2 0.3 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase DHO_dh PF01180.21 KXH34617.1 - 0.014 14.7 0.1 0.043 13.0 0.0 1.7 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase His_biosynth PF00977.21 KXH34617.1 - 0.032 13.7 0.2 0.66 9.4 0.0 2.5 3 0 0 3 3 3 0 Histidine biosynthesis protein PIF1 PF05970.14 KXH34618.1 - 1.1e-29 103.7 2.1 4.3e-20 72.2 0.1 3.1 2 2 1 3 3 3 2 PIF1-like helicase AAA_30 PF13604.6 KXH34618.1 - 2e-14 53.8 0.0 2.4e-09 37.2 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_19 PF13245.6 KXH34618.1 - 9.7e-08 32.5 0.0 1.6e-06 28.5 0.0 2.7 2 1 0 2 2 2 1 AAA domain Herpes_Helicase PF02689.14 KXH34618.1 - 9.2e-07 27.2 0.0 2.4e-06 25.8 0.0 1.5 2 0 0 2 2 2 1 Helicase AAA PF00004.29 KXH34618.1 - 2.5e-05 24.7 0.0 6.4e-05 23.4 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) UvrD_C_2 PF13538.6 KXH34618.1 - 0.00056 19.7 0.0 0.0016 18.2 0.0 1.9 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 KXH34618.1 - 0.0035 17.1 0.3 5.3 6.7 0.4 3.3 3 1 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_5 PF07728.14 KXH34618.1 - 0.0092 16.0 0.1 0.03 14.3 0.1 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KXH34618.1 - 0.0093 16.4 0.0 0.021 15.2 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 KXH34618.1 - 0.012 15.4 0.2 0.99 9.1 0.0 2.6 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system Helicase_RecD PF05127.14 KXH34618.1 - 0.047 13.5 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Helicase ABC_tran PF00005.27 KXH34618.1 - 0.061 13.8 0.1 0.17 12.4 0.1 1.8 1 1 0 1 1 1 0 ABC transporter RsgA_GTPase PF03193.16 KXH34618.1 - 0.061 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_22 PF13401.6 KXH34618.1 - 0.091 13.0 0.2 0.6 10.4 0.2 2.1 1 1 0 1 1 1 0 AAA domain DUF815 PF05673.13 KXH34618.1 - 0.15 11.2 0.0 0.27 10.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) adh_short PF00106.25 KXH34619.1 - 1.8e-32 112.4 0.0 2.5e-32 111.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXH34619.1 - 1.9e-18 66.9 0.0 3.9e-18 65.9 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KXH34619.1 - 0.0073 15.8 0.0 0.018 14.5 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KXH34620.1 - 1.2e-09 38.3 0.0 3.2e-09 36.9 0.0 1.6 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 KXH34620.1 - 2.7e-06 27.1 0.0 3.5e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 KXH34620.1 - 0.0051 16.3 0.0 0.0073 15.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 KXH34620.1 - 0.015 15.4 0.0 0.026 14.6 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Semialdhyde_dh PF01118.24 KXH34620.1 - 0.037 14.5 0.0 0.058 13.8 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Ldh_1_N PF00056.23 KXH34620.1 - 0.04 14.0 0.0 0.096 12.8 0.1 1.7 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain NAD_binding_4 PF07993.12 KXH34620.1 - 0.07 12.3 0.0 0.14 11.3 0.0 1.5 1 0 0 1 1 1 0 Male sterility protein Zn_clus PF00172.18 KXH34621.1 - 2.1e-07 30.9 9.8 3.2e-07 30.3 9.8 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain F-box-like PF12937.7 KXH34623.1 - 0.037 13.9 0.3 0.089 12.7 0.3 1.6 1 0 0 1 1 1 0 F-box-like LIAS_N PF16881.5 KXH34625.1 - 9.3e-18 64.6 0.0 1.9e-17 63.6 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of lipoyl synthase of Radical_SAM family Radical_SAM PF04055.21 KXH34625.1 - 4.5e-12 46.7 0.0 8.6e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Spore_GerAC PF05504.11 KXH34625.1 - 0.035 14.3 0.0 0.055 13.7 0.0 1.3 1 0 0 1 1 1 0 Spore germination B3/ GerAC like, C-terminal Type2_restr_D3 PF16902.5 KXH34625.1 - 0.085 12.8 0.0 0.61 10.0 0.0 2.1 2 0 0 2 2 2 0 Type-2 restriction enzyme D3 domain Pectate_lyase_3 PF12708.7 KXH34626.1 - 6.1e-90 300.8 11.1 3.5e-80 268.9 0.7 3.4 3 0 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 KXH34626.1 - 8.1e-07 28.6 0.8 0.024 14.3 0.1 2.6 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Methyltrn_RNA_3 PF02598.17 KXH34627.1 - 5.2e-101 337.9 0.0 6e-101 337.7 0.0 1.0 1 0 0 1 1 1 1 Putative RNA methyltransferase Thioredoxin PF00085.20 KXH34628.1 - 5.3e-26 90.6 0.0 7.7e-26 90.1 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KXH34628.1 - 5.1e-07 30.1 0.0 1.2e-06 28.9 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KXH34628.1 - 7e-06 26.3 0.0 2.7e-05 24.4 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin-like OST3_OST6 PF04756.13 KXH34628.1 - 1.1e-05 24.9 0.0 1.5e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_9 PF14595.6 KXH34628.1 - 0.00057 19.7 0.0 0.00079 19.2 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 KXH34628.1 - 0.0013 18.7 0.0 0.0022 17.9 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KXH34628.1 - 0.0064 16.2 0.0 0.0098 15.6 0.0 1.4 1 0 0 1 1 1 1 Redoxin Thioredoxin_7 PF13899.6 KXH34628.1 - 0.025 14.8 0.0 0.039 14.1 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like HyaE PF07449.11 KXH34628.1 - 0.072 13.1 0.0 0.42 10.6 0.0 1.9 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE SelK_SelG PF10961.8 KXH34628.1 - 0.15 12.7 0.1 0.38 11.4 0.0 1.7 1 1 1 2 2 2 0 Selenoprotein SelK_SelG Thioredoxin_4 PF13462.6 KXH34628.1 - 0.15 12.2 0.7 2.6 8.2 0.0 2.1 1 1 1 2 2 2 0 Thioredoxin Ank_2 PF12796.7 KXH34629.1 - 2.4e-76 252.4 18.4 4.8e-15 55.9 0.3 7.2 3 1 5 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXH34629.1 - 1.9e-53 178.2 5.3 1.7e-09 38.0 0.0 8.4 4 2 4 9 9 8 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXH34629.1 - 4.7e-53 176.6 7.1 7.7e-10 38.8 0.1 9.6 3 3 7 10 10 10 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXH34629.1 - 5.2e-48 155.4 4.2 0.00011 22.3 0.0 12.8 12 0 0 12 12 12 9 Ankyrin repeat Ank PF00023.30 KXH34629.1 - 1.8e-43 145.2 5.3 0.00017 21.9 0.0 13.2 12 1 0 12 12 12 9 Ankyrin repeat HET PF06985.11 KXH34629.1 - 6.3e-11 42.8 14.7 5.6e-10 39.7 0.0 3.6 2 2 1 3 3 3 2 Heterokaryon incompatibility protein (HET) DHR10 PF18595.1 KXH34629.1 - 0.00028 20.9 7.5 0.0034 17.4 9.2 2.0 2 0 0 2 2 2 1 Designed helical repeat protein 10 domain ERM PF00769.19 KXH34629.1 - 0.033 14.0 12.2 0.057 13.2 12.2 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family FAM180 PF15173.6 KXH34629.1 - 0.038 14.0 0.4 0.097 12.7 0.4 1.7 1 0 0 1 1 1 0 FAM180 family DUF4140 PF13600.6 KXH34629.1 - 0.15 12.5 2.3 0.54 10.7 2.3 2.0 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DivIVA PF05103.13 KXH34629.1 - 0.31 11.1 9.3 1 9.4 9.3 1.9 1 1 0 1 1 1 0 DivIVA protein Rsm22 PF09243.10 KXH34630.1 - 6.9e-29 101.0 0.0 2.2e-28 99.3 0.0 1.8 1 1 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_23 PF13489.6 KXH34630.1 - 0.00017 21.4 0.0 0.00056 19.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH34630.1 - 0.0028 18.3 0.3 0.094 13.4 0.0 3.0 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH34630.1 - 0.0062 16.3 0.1 0.32 10.8 0.0 3.0 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH34630.1 - 0.018 15.8 0.6 0.068 13.9 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.12 KXH34630.1 - 0.045 14.4 0.0 0.51 11.0 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase domain TP_methylase PF00590.20 KXH34631.1 - 1.2e-45 156.1 0.2 2.1e-45 155.3 0.2 1.4 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.6 KXH34631.1 - 5.1e-14 52.6 0.0 1.1e-13 51.6 0.0 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 KXH34631.1 - 4.8e-11 42.1 1.0 6.5e-10 38.5 1.0 2.2 1 1 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.6 KXH34631.1 - 7.7e-11 41.3 0.0 1.7e-10 40.1 0.0 1.7 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central AAA_16 PF13191.6 KXH34632.1 - 0.032 14.6 0.1 0.34 11.3 0.0 2.6 3 0 0 3 3 3 0 AAA ATPase domain AnmK PF03702.14 KXH34632.1 - 0.078 12.1 0.1 0.17 11.0 0.1 1.4 1 0 0 1 1 1 0 Anhydro-N-acetylmuramic acid kinase TsaE PF02367.17 KXH34632.1 - 0.11 12.5 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 KXH34632.1 - 0.16 12.2 0.0 2.7 8.3 0.0 2.7 2 1 0 2 2 2 0 AAA domain Zn_clus PF00172.18 KXH34633.1 - 6e-05 23.1 10.9 9.8e-05 22.4 10.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Med3 PF11593.8 KXH34633.1 - 0.13 11.4 4.4 0.24 10.5 4.4 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Beta-lactamase PF00144.24 KXH34634.1 - 5.8e-18 65.2 0.0 1e-17 64.4 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.8 KXH34634.1 - 0.013 15.9 0.0 0.099 13.1 0.0 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF3471) GST_N_4 PF17172.4 KXH34635.1 - 3.9e-22 78.9 0.0 7.2e-22 78.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 KXH34635.1 - 5.6e-07 29.2 0.0 1.2e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 KXH34635.1 - 6.3e-05 23.3 0.0 0.00014 22.1 0.0 1.6 1 1 1 2 2 2 1 Outer mitochondrial membrane transport complex protein GST_C_2 PF13410.6 KXH34635.1 - 0.00075 19.5 0.2 0.0014 18.6 0.1 1.7 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KXH34635.1 - 0.018 15.5 0.1 0.053 13.9 0.1 1.8 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain FAD_binding_3 PF01494.19 KXH34636.1 - 3.4e-51 174.6 0.0 4.4e-51 174.2 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 KXH34636.1 - 1.3e-08 34.3 0.0 6.9e-06 25.4 0.2 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 KXH34636.1 - 6.1e-08 32.6 2.6 9.9e-07 28.7 0.3 2.5 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KXH34636.1 - 2.2e-06 27.3 0.9 1.9e-05 24.2 0.9 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXH34636.1 - 2.3e-06 27.7 0.3 5.5e-06 26.5 0.3 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KXH34636.1 - 5.9e-06 26.7 0.3 0.0096 16.5 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXH34636.1 - 5.9e-06 25.2 0.1 1.1e-05 24.3 0.1 1.4 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.14 KXH34636.1 - 1.4e-05 24.5 0.1 0.00044 19.6 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXH34636.1 - 0.00019 20.8 0.0 0.00034 20.0 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXH34636.1 - 0.00022 20.6 0.1 0.00038 19.8 0.1 1.3 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.22 KXH34636.1 - 0.0024 17.1 0.1 0.0035 16.5 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 KXH34636.1 - 0.004 16.2 0.3 0.0059 15.7 0.3 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein ApbA PF02558.16 KXH34636.1 - 0.0065 16.1 0.1 0.012 15.2 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.6 KXH34636.1 - 0.013 16.0 0.0 0.03 14.8 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.14 KXH34636.1 - 0.12 12.0 0.1 0.22 11.0 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AlaDh_PNT_C PF01262.21 KXH34636.1 - 0.13 11.5 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Trp_halogenase PF04820.14 KXH34636.1 - 0.17 10.7 0.4 0.28 10.0 0.1 1.5 2 0 0 2 2 2 0 Tryptophan halogenase ThiF PF00899.21 KXH34636.1 - 0.17 11.2 0.2 0.32 10.3 0.2 1.3 1 0 0 1 1 1 0 ThiF family Aldedh PF00171.22 KXH34637.1 - 4.3e-75 253.0 0.0 4.9e-75 252.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family MFS_1 PF07690.16 KXH34638.1 - 2.1e-17 63.1 15.7 2.1e-17 63.1 15.7 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF2157 PF09925.9 KXH34638.1 - 0.16 11.7 0.1 0.16 11.7 0.1 3.2 3 1 0 3 3 3 0 Predicted membrane protein (DUF2157) COX14 PF14880.6 KXH34638.1 - 0.24 11.3 0.0 0.24 11.3 0.0 2.9 3 0 0 3 3 3 0 Cytochrome oxidase c assembly Epimerase PF01370.21 KXH34639.1 - 1.1e-12 47.9 0.0 1.5e-12 47.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KXH34639.1 - 5.8e-07 29.6 0.0 8.9e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KXH34639.1 - 0.012 15.0 0.0 0.017 14.5 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase NmrA PF05368.13 KXH34639.1 - 0.041 13.4 0.0 0.63 9.6 0.1 2.3 2 1 0 2 2 2 0 NmrA-like family UBA_2 PF08587.11 KXH34639.1 - 0.16 12.1 0.0 0.35 11.0 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin associated domain (UBA) Glyco_hydro_11 PF00457.17 KXH34640.1 - 2.8e-60 203.0 12.3 3.3e-60 202.8 12.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 NmrA PF05368.13 KXH34641.1 - 1.3e-21 77.2 0.0 1.4e-21 77.1 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXH34641.1 - 1.2e-07 31.9 0.0 2.8e-07 30.6 0.0 1.7 1 1 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KXH34641.1 - 3.9e-05 23.9 0.1 0.0063 16.8 0.0 2.2 2 0 0 2 2 2 2 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 KXH34641.1 - 0.0001 22.7 0.0 0.00019 21.8 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 KXH34641.1 - 0.00018 21.6 0.0 0.00037 20.6 0.0 1.6 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus DXP_reductoisom PF02670.16 KXH34641.1 - 0.021 15.5 0.1 0.22 12.3 0.0 2.1 2 0 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase MFS_1 PF07690.16 KXH34642.1 - 1.6e-41 142.4 34.2 1.6e-41 142.4 34.2 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH34642.1 - 1.6e-10 40.4 9.8 1.6e-10 40.4 9.8 2.4 3 0 0 3 3 3 1 Sugar (and other) transporter OATP PF03137.20 KXH34642.1 - 0.025 12.9 3.1 0.02 13.2 1.0 1.9 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family SH3_9 PF14604.6 KXH34643.1 - 1e-05 25.3 3.4 0.00094 19.0 0.2 2.8 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.17 KXH34643.1 - 0.0024 17.5 0.2 0.0024 17.5 0.2 2.2 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 KXH34643.1 - 0.65 9.7 5.3 0.11 12.2 0.8 2.0 2 0 0 2 2 2 0 SH3 domain GPI-anchored PF10342.9 KXH34644.1 - 1.6e-14 54.4 0.4 1.6e-14 54.4 0.4 2.6 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family SOG2 PF10428.9 KXH34644.1 - 2.5 7.2 17.0 2.6 7.1 17.0 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein DUF3275 PF11679.8 KXH34644.1 - 4.3 7.3 8.0 0.29 11.1 0.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3275) Methyltransf_23 PF13489.6 KXH34645.1 - 2.6e-25 89.2 0.0 4.2e-25 88.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH34645.1 - 1.2e-10 41.4 0.0 1.3e-09 38.1 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH34645.1 - 3.9e-10 40.3 0.0 1.3e-09 38.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH34645.1 - 7.9e-08 32.8 0.0 2.7e-07 31.2 0.0 1.9 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH34645.1 - 2.1e-07 31.6 0.0 1.9e-06 28.5 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain CheR PF01739.18 KXH34645.1 - 0.001 18.6 0.0 0.0019 17.7 0.0 1.4 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain FtsJ PF01728.19 KXH34645.1 - 0.0017 18.5 0.0 0.0034 17.5 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase PrmA PF06325.13 KXH34645.1 - 0.004 16.6 0.0 0.0062 16.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KXH34645.1 - 0.01 15.4 0.0 0.037 13.6 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_16 PF10294.9 KXH34645.1 - 0.032 14.0 0.0 0.058 13.1 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase Ubie_methyltran PF01209.18 KXH34645.1 - 0.054 12.8 0.0 18 4.6 0.0 2.9 2 1 1 3 3 3 0 ubiE/COQ5 methyltransferase family Ribosomal_S16 PF00886.19 KXH34646.1 - 1e-24 86.3 0.1 1.8e-24 85.5 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S16 Aa_trans PF01490.18 KXH34647.1 - 3.1e-82 276.5 15.6 3.1e-82 276.5 15.6 1.3 2 0 0 2 2 2 1 Transmembrane amino acid transporter protein Dynactin_p22 PF07426.11 KXH34648.1 - 5.6e-08 32.8 0.0 2.2e-07 30.9 0.0 1.9 1 1 1 2 2 2 1 Dynactin subunit p22 SH3_1 PF00018.28 KXH34649.1 - 1.3e-09 37.5 0.2 5.3e-09 35.5 0.1 2.0 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 KXH34649.1 - 6.1e-07 29.2 0.0 1.2e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KXH34649.1 - 1.1e-05 25.0 0.0 2.2e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain MARVEL PF01284.23 KXH34649.1 - 0.19 11.7 13.7 0.29 11.1 13.7 1.2 1 0 0 1 1 1 0 Membrane-associating domain DUF2417 PF10329.9 KXH34649.1 - 0.69 9.3 10.4 1.1 8.6 10.4 1.3 1 0 0 1 1 1 0 Region of unknown function (DUF2417) MpPF26 PF07666.11 KXH34649.1 - 7.6 6.7 7.8 2.1 8.5 1.3 2.1 1 1 1 2 2 2 0 M penetrans paralogue family 26 DASH_Spc19 PF08287.11 KXH34650.1 - 7e-49 165.7 0.0 9e-49 165.4 0.0 1.1 1 0 0 1 1 1 1 Spc19 SlyX PF04102.12 KXH34650.1 - 0.0059 17.2 0.7 0.069 13.8 0.1 2.6 3 0 0 3 3 3 1 SlyX DJ-1_PfpI PF01965.24 KXH34651.1 - 2e-09 37.4 0.0 2.5e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family DUF1651 PF07864.11 KXH34651.1 - 0.27 11.6 3.2 7.2 7.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1651) YjeF_N PF03853.15 KXH34652.1 - 6.6e-32 110.7 0.0 8.1e-32 110.5 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus LRR_4 PF12799.7 KXH34653.1 - 0.13 12.8 0.0 0.34 11.4 0.0 1.7 1 0 0 1 1 1 0 Leucine Rich repeats (2 copies) Methyltransf_9 PF08003.11 KXH34655.1 - 0.037 13.0 0.0 0.052 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) DAO_C PF16901.5 KXH34677.1 - 0.0039 17.1 0.0 0.045 13.6 0.0 2.2 2 0 0 2 2 2 1 C-terminal domain of alpha-glycerophosphate oxidase Ribosomal_60s PF00428.19 KXH34677.1 - 0.056 14.0 0.2 0.14 12.8 0.2 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF3383 PF11863.8 KXH34677.1 - 0.074 12.1 5.3 0.11 11.5 5.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3383) zf-C2H2 PF00096.26 KXH34677.1 - 4.8 7.8 11.9 0.59 10.7 1.6 3.3 3 0 0 3 3 3 0 Zinc finger, C2H2 type DUF3632 PF12311.8 KXH34678.1 - 4e-31 108.8 1.6 9.6e-31 107.6 1.6 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Dehydrin PF00257.19 KXH34678.1 - 0.45 11.1 7.2 0.2 12.2 3.0 2.3 2 0 0 2 2 2 0 Dehydrin MRP-L28 PF09812.9 KXH34680.1 - 0.0065 16.6 0.6 0.0073 16.4 0.6 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 DUF3439 PF11921.8 KXH34680.1 - 0.089 12.8 3.7 0.13 12.2 3.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Ras PF00071.22 KXH34681.1 - 1.4e-51 174.3 0.0 1.6e-51 174.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXH34681.1 - 1.5e-22 80.0 0.0 2.1e-22 79.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXH34681.1 - 2.9e-06 26.8 0.0 4.4e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KXH34681.1 - 0.011 15.1 0.0 0.014 14.7 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KXH34681.1 - 0.012 15.2 0.0 0.046 13.3 0.0 1.7 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain SRPRB PF09439.10 KXH34681.1 - 0.047 13.1 0.0 0.062 12.7 0.0 1.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KXH34681.1 - 0.077 13.1 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase PduV-EutP PF10662.9 KXH34681.1 - 0.18 11.5 0.0 4.7 6.9 0.0 2.4 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NST1 PF13945.6 KXH34682.1 - 1e-52 179.0 16.9 1e-52 179.0 16.9 5.3 4 2 1 5 5 5 1 Salt tolerance down-regulator TFIIA PF03153.13 KXH34682.1 - 1.3e-05 25.5 18.7 1.3e-05 25.5 18.7 4.0 2 1 2 4 4 4 1 Transcription factor IIA, alpha/beta subunit PS_Dcarbxylase PF02666.15 KXH34683.1 - 4.8e-45 153.6 0.0 6.2e-45 153.2 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase p450 PF00067.22 KXH34684.1 - 1.9e-67 228.0 0.0 2.3e-67 227.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KXH34685.1 - 5.6e-64 216.6 0.0 6.9e-64 216.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 WD40 PF00400.32 KXH34688.1 - 4.1e-30 103.4 9.1 6.8e-07 29.9 0.5 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXH34688.1 - 1.5e-08 34.8 0.1 0.12 12.7 0.0 4.8 3 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KXH34688.1 - 1.1e-05 24.3 6.0 0.024 13.3 0.3 4.7 3 2 2 5 5 5 3 Nucleoporin Nup120/160 DUF5082 PF16888.5 KXH34688.1 - 0.028 14.7 0.2 0.067 13.5 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) APG6_N PF17675.1 KXH34688.1 - 0.11 13.0 3.0 0.27 11.8 3.0 1.7 1 0 0 1 1 1 0 Apg6 coiled-coil region Glyco_hydro_18 PF00704.28 KXH34696.1 - 3.2e-67 227.5 0.0 3.7e-67 227.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Methyltransf_23 PF13489.6 KXH34697.1 - 2.1e-18 66.7 0.0 3.1e-18 66.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH34697.1 - 1e-09 39.0 0.0 3.1e-09 37.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH34697.1 - 2.6e-09 37.7 0.0 1.5e-08 35.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH34697.1 - 6.4e-09 35.8 0.0 0.0002 21.2 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 KXH34697.1 - 5.1e-07 30.2 0.0 9.4e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KXH34697.1 - 0.0047 16.4 0.0 0.0086 15.6 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.13 KXH34697.1 - 0.007 15.8 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 KXH34697.1 - 0.018 14.4 0.0 0.12 11.7 0.0 2.0 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 KXH34697.1 - 0.047 13.0 0.0 0.085 12.1 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase domain MTS PF05175.14 KXH34697.1 - 0.054 13.0 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain GidB PF02527.15 KXH34697.1 - 0.079 12.3 0.0 0.52 9.6 0.0 2.0 1 1 0 1 1 1 0 rRNA small subunit methyltransferase G CMAS PF02353.20 KXH34697.1 - 0.13 11.5 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase zf-CCCH PF00642.24 KXH34698.1 - 1.7e-21 75.6 32.4 6.4e-08 32.3 0.7 5.4 4 1 1 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KXH34698.1 - 4.9e-20 70.9 30.9 1.1e-06 28.4 1.9 5.4 5 0 0 5 5 5 5 Zinc finger domain Torus PF16131.5 KXH34698.1 - 5.6e-12 46.3 23.7 0.00051 20.7 0.5 5.3 1 1 4 5 5 5 5 Torus domain zf-CCCH_4 PF18044.1 KXH34698.1 - 3.6e-08 33.0 36.7 9.6e-06 25.3 0.4 5.6 5 0 0 5 5 5 4 CCCH-type zinc finger zf-CCCH_3 PF15663.5 KXH34698.1 - 0.0039 17.4 1.4 0.0039 17.4 1.4 2.8 1 1 2 3 3 3 2 Zinc-finger containing family zf-C3H1 PF10650.9 KXH34698.1 - 0.57 10.0 4.0 2.4 8.0 0.4 3.5 3 0 0 3 3 3 0 Putative zinc-finger domain Glyco_hydro_31 PF01055.26 KXH34699.1 - 6.7e-144 480.3 4.7 8.5e-144 480.0 4.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 KXH34699.1 - 3.6e-33 114.2 0.0 6.3e-33 113.4 0.0 1.4 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Sulf_coat_C PF12193.8 KXH34700.1 - 0.015 15.3 0.1 0.03 14.4 0.1 1.4 1 0 0 1 1 1 0 Sulfolobus virus coat protein C terminal Glyco_transf_28 PF03033.20 KXH34701.1 - 0.06 13.4 0.0 0.074 13.1 0.0 1.1 1 0 0 1 1 1 0 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 KXH34702.1 - 2.1e-12 46.6 0.0 3.6e-12 45.8 0.0 1.3 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 KXH34702.1 - 0.13 12.3 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain p450 PF00067.22 KXH34703.1 - 5e-70 236.5 0.0 1.8e-69 234.7 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 FANC_SAP PF18081.1 KXH34703.1 - 0.12 12.5 0.3 0.32 11.2 0.1 1.8 2 0 0 2 2 2 0 Fanconi anemia-associated nuclease SAP domain Prefoldin_3 PF13758.6 KXH34704.1 - 4.6e-33 113.2 2.0 4.6e-33 113.2 2.0 2.0 2 0 0 2 2 2 1 Prefoldin subunit DUF3835 PF12927.7 KXH34704.1 - 2.4e-19 69.9 0.4 2.4e-19 69.9 0.4 4.3 5 0 0 5 5 5 1 Domain of unknown function (DUF3835) Prefoldin_2 PF01920.20 KXH34704.1 - 0.092 12.7 11.4 0.92 9.5 0.1 3.8 4 0 0 4 4 4 0 Prefoldin subunit Prefoldin PF02996.17 KXH34704.1 - 0.14 12.0 1.9 13 5.7 0.1 2.8 2 0 0 2 2 2 0 Prefoldin subunit FAA_hydro_N_2 PF18288.1 KXH34704.1 - 0.34 11.4 2.2 0.45 11.0 0.6 2.0 2 0 0 2 2 2 0 Fumarylacetoacetase N-terminal domain 2 Lzipper-MIP1 PF14389.6 KXH34704.1 - 0.82 10.0 5.2 1.1 9.5 0.8 3.1 2 1 1 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 Laminin_II PF06009.12 KXH34704.1 - 2.5 8.1 6.3 18 5.3 1.0 2.8 2 1 0 2 2 2 0 Laminin Domain II TMF_DNA_bd PF12329.8 KXH34704.1 - 2.7 8.1 9.4 35 4.5 0.3 3.9 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF4337 PF14235.6 KXH34704.1 - 5.5 7.1 6.9 12 6.0 0.9 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) Uds1 PF15456.6 KXH34704.1 - 7.5 6.7 8.9 15 5.7 2.4 2.9 2 1 0 2 2 2 0 Up-regulated During Septation CS PF04969.16 KXH34705.1 - 2.1e-18 67.1 0.1 4e-18 66.2 0.1 1.5 1 0 0 1 1 1 1 CS domain MAT1 PF06391.13 KXH34706.1 - 3.4e-36 125.0 5.1 4.2e-36 124.7 5.1 1.2 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_5 PF17121.5 KXH34706.1 - 6.2e-30 102.9 10.1 9.7e-30 102.2 10.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXH34706.1 - 0.0011 18.7 3.6 0.0028 17.5 3.7 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KXH34706.1 - 0.004 17.0 6.0 0.0066 16.3 6.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXH34706.1 - 0.0097 15.7 5.6 0.028 14.3 5.7 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Plug PF07715.15 KXH34706.1 - 0.087 13.4 0.0 0.15 12.6 0.0 1.4 1 0 0 1 1 1 0 TonB-dependent Receptor Plug Domain zf-RING_2 PF13639.6 KXH34706.1 - 0.088 13.2 6.3 0.16 12.4 6.3 1.4 1 0 0 1 1 1 0 Ring finger domain MRP-S26 PF14943.6 KXH34706.1 - 0.091 12.7 10.9 0.15 11.9 10.9 1.3 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 Zn_ribbon_17 PF17120.5 KXH34706.1 - 0.15 11.7 2.1 0.28 10.8 2.1 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 KXH34706.1 - 0.87 9.7 5.7 1.6 8.9 5.7 1.4 1 0 0 1 1 1 0 RING-type zinc-finger zf-UDP PF14569.6 KXH34706.1 - 1 9.6 5.3 3 8.0 5.2 1.7 1 1 0 1 1 1 0 Zinc-binding RING-finger zf-RING_5 PF14634.6 KXH34706.1 - 1.6 8.8 9.5 13 5.8 9.8 2.1 1 1 1 2 2 2 0 zinc-RING finger domain zf-RING_4 PF14570.6 KXH34706.1 - 1.8 8.4 10.7 35 4.3 11.7 2.2 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain ANTH PF07651.16 KXH34707.1 - 5.6e-67 225.6 0.1 7.2e-67 225.3 0.1 1.1 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.20 KXH34707.1 - 1.3e-06 28.4 0.0 2.2e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 ENTH domain tRNA-synt_2 PF00152.20 KXH34708.1 - 7.7e-87 291.3 0.0 1.5e-86 290.3 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.25 KXH34708.1 - 0.11 12.5 0.0 0.15 12.0 0.0 1.5 1 1 0 1 1 1 0 tRNA synthetase class II core domain (G, H, P, S and T) VPS13_C PF16909.5 KXH34709.1 - 0.51 10.1 2.8 0.63 9.8 2.2 1.5 1 1 0 1 1 1 0 Vacuolar-sorting-associated 13 protein C-terminal ELO PF01151.18 KXH34710.1 - 7e-61 205.9 16.2 9e-61 205.6 16.2 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family PsbX PF06596.11 KXH34710.1 - 0.073 13.1 0.5 0.073 13.1 0.5 2.3 2 0 0 2 2 2 0 Photosystem II reaction centre X protein (PsbX) MFS_1 PF07690.16 KXH34711.1 - 1.7e-38 132.5 50.3 3.1e-38 131.6 50.3 1.5 1 0 0 1 1 1 1 Major Facilitator Superfamily T4SS_CagC PF16943.5 KXH34711.1 - 0.005 17.0 0.3 3.4 7.9 0.1 3.1 2 0 0 2 2 2 2 Cag pathogenicity island, type IV secretory system SMN PF06003.12 KXH34711.1 - 5.7 6.1 5.6 32 3.7 2.9 2.5 2 1 0 2 2 2 0 Survival motor neuron protein (SMN) Pilin_N PF07790.11 KXH34712.1 - 0.016 16.1 1.3 0.033 15.1 1.3 1.6 1 0 0 1 1 1 0 Archaeal Type IV pilin, N-terminal DUF3357 PF11837.8 KXH34712.1 - 0.048 14.1 1.3 0.087 13.3 1.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) PAN_1 PF00024.26 KXH34712.1 - 0.066 13.2 0.0 0.17 11.9 0.0 1.7 1 0 0 1 1 1 0 PAN domain Pyr_redox_2 PF07992.14 KXH34713.1 - 2.9e-51 174.4 1.4 4.2e-51 173.9 1.4 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXH34713.1 - 2.9e-19 69.5 0.1 1.8e-17 63.6 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXH34713.1 - 1.4e-18 67.2 1.6 1.4e-16 60.8 0.6 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 KXH34713.1 - 1.7e-06 28.4 0.1 0.00045 20.6 0.0 2.5 2 1 0 2 2 2 1 Putative NAD(P)-binding Thi4 PF01946.17 KXH34713.1 - 3.5e-05 23.2 0.2 0.00033 20.0 0.0 2.2 2 0 0 2 2 2 1 Thi4 family K_oxygenase PF13434.6 KXH34713.1 - 5.9e-05 22.4 0.3 0.046 12.9 0.1 3.5 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Shikimate_DH PF01488.20 KXH34713.1 - 0.00012 22.1 0.5 0.19 11.8 0.1 3.0 2 1 1 3 3 3 2 Shikimate / quinate 5-dehydrogenase DAO PF01266.24 KXH34713.1 - 0.00016 21.4 2.3 2.6 7.6 0.0 3.3 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXH34713.1 - 0.00069 19.8 3.2 0.049 13.9 0.0 2.8 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 KXH34713.1 - 0.00078 18.6 5.2 0.69 8.9 0.4 4.1 3 1 1 4 4 4 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 KXH34713.1 - 0.0044 16.1 6.9 0.3 10.1 0.6 3.3 3 1 0 4 4 4 2 FAD binding domain FAD_oxidored PF12831.7 KXH34713.1 - 0.022 14.1 0.1 0.041 13.2 0.1 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KXH34713.1 - 0.029 13.6 1.3 3.1 6.9 0.0 2.9 2 1 1 3 3 3 0 FAD binding domain Trp_halogenase PF04820.14 KXH34713.1 - 0.029 13.2 0.2 0.53 9.1 0.0 2.3 3 0 0 3 3 3 0 Tryptophan halogenase NAD_binding_9 PF13454.6 KXH34713.1 - 0.063 13.3 0.0 3 7.8 0.0 2.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding AIRC PF00731.20 KXH34713.1 - 0.07 12.7 0.2 0.14 11.7 0.2 1.5 1 0 0 1 1 1 0 AIR carboxylase HI0933_like PF03486.14 KXH34713.1 - 0.12 11.1 0.5 3.4 6.2 0.1 2.9 2 1 0 3 3 3 0 HI0933-like protein DUF4448 PF14610.6 KXH34715.1 - 2.2e-42 145.0 0.0 2.9e-42 144.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) GNAT_acetyltr_2 PF13718.6 KXH34717.1 - 2e-95 318.5 0.0 3.9e-95 317.6 0.0 1.5 1 0 0 1 1 1 1 GNAT acetyltransferase 2 tRNA_bind_2 PF13725.6 KXH34717.1 - 4.2e-92 308.1 0.0 7.7e-92 307.2 0.0 1.4 1 0 0 1 1 1 1 Possible tRNA binding domain Helicase_RecD PF05127.14 KXH34717.1 - 6e-66 221.6 0.0 2.9e-65 219.4 0.0 2.2 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.11 KXH34717.1 - 7.7e-34 115.5 0.0 2.1e-33 114.1 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) AAA_30 PF13604.6 KXH34717.1 - 9.7e-05 22.2 0.2 0.0064 16.2 0.1 2.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KXH34717.1 - 0.0014 18.9 0.0 0.072 13.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain GHMP_kinases_N PF00288.26 KXH34717.1 - 0.073 13.3 0.1 0.18 12.0 0.1 1.7 1 0 0 1 1 1 0 GHMP kinases N terminal domain DUF1713 PF08213.11 KXH34718.1 - 6.6e-10 38.7 22.2 6.6e-10 38.7 22.2 1.9 2 0 0 2 2 2 1 Mitochondrial domain of unknown function (DUF1713) Pet20 PF08692.10 KXH34718.1 - 0.0049 17.6 0.4 0.014 16.1 0.0 2.0 2 0 0 2 2 2 1 Mitochondrial protein Pet20 PhyH PF05721.13 KXH34719.1 - 1.4e-08 35.3 0.0 5.7e-07 30.0 0.0 2.4 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) NLPC_P60 PF00877.19 KXH34719.1 - 0.019 15.0 0.0 0.03 14.4 0.0 1.3 1 0 0 1 1 1 0 NlpC/P60 family 2OG-FeII_Oxy_3 PF13640.6 KXH34719.1 - 0.036 15.0 0.0 0.07 14.0 0.0 1.4 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Mpv17_PMP22 PF04117.12 KXH34720.1 - 2.8e-24 85.1 0.3 5e-24 84.3 0.3 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family DUF1664 PF07889.12 KXH34721.1 - 0.021 14.8 1.1 0.06 13.4 0.4 1.9 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) GAS PF13851.6 KXH34721.1 - 0.039 13.3 0.2 0.063 12.6 0.2 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF2312 PF10073.9 KXH34721.1 - 0.042 13.5 0.6 0.084 12.5 0.6 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2312) SesA PF17107.5 KXH34721.1 - 0.042 14.0 0.2 0.069 13.3 0.2 1.3 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Swi5 PF07061.11 KXH34721.1 - 0.1 12.7 0.1 11 6.2 0.0 2.4 2 0 0 2 2 2 0 Swi5 Fmp27_WPPW PF10359.9 KXH34721.1 - 0.11 11.4 0.3 0.14 11.0 0.3 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain PKcGMP_CC PF16808.5 KXH34721.1 - 0.14 12.0 0.2 0.14 12.0 0.2 2.6 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Rx_N PF18052.1 KXH34721.1 - 0.19 12.1 3.7 0.44 10.9 3.8 1.6 1 1 0 1 1 1 0 Rx N-terminal domain Latarcin PF10279.9 KXH34721.1 - 0.27 11.7 2.6 4.7 7.7 0.2 2.4 1 1 1 2 2 2 0 Latarcin precursor NPV_P10 PF05531.12 KXH34721.1 - 0.46 11.0 2.7 2.7 8.5 1.3 2.3 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein SesA PF17107.5 KXH34722.1 - 0.0096 16.1 1.6 0.037 14.2 1.2 2.0 2 0 0 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases Rx_N PF18052.1 KXH34722.1 - 0.017 15.3 0.5 0.041 14.2 0.5 1.6 1 0 0 1 1 1 0 Rx N-terminal domain zf-RanBP PF00641.18 KXH34723.1 - 0.051 12.9 1.5 0.051 12.9 1.5 2.4 3 0 0 3 3 3 0 Zn-finger in Ran binding protein and others DNA_pol_phi PF04931.13 KXH34724.1 - 0.83 7.7 3.8 1 7.4 3.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi CENP-B_dimeris PF09026.10 KXH34724.1 - 5 7.6 7.9 9.5 6.7 6.3 2.1 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Spt5_N PF11942.8 KXH34724.1 - 5.5 8.0 13.3 17 6.4 13.3 1.8 1 1 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal Methyltransf_23 PF13489.6 KXH34725.1 - 1.2e-22 80.5 0.0 1.7e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH34725.1 - 7.3e-12 45.8 0.0 2.4e-11 44.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH34725.1 - 5.2e-11 42.6 0.0 6.4e-10 39.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH34725.1 - 2.9e-09 37.5 0.0 8e-09 36.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH34725.1 - 6.4e-07 30.1 0.0 7.4e-06 26.6 0.0 2.5 2 1 0 2 2 1 1 Methyltransferase domain PrmA PF06325.13 KXH34725.1 - 1.5e-05 24.5 0.0 2.5e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KXH34725.1 - 0.00045 19.8 0.0 0.00084 18.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.18 KXH34725.1 - 0.005 16.1 0.0 0.21 10.8 0.0 2.4 3 0 0 3 3 3 1 O-methyltransferase domain CheR PF01739.18 KXH34725.1 - 0.017 14.6 0.0 0.034 13.6 0.0 1.4 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Methyltransf_4 PF02390.17 KXH34725.1 - 0.023 14.2 0.0 1.1 8.8 0.0 2.3 2 0 0 2 2 2 0 Putative methyltransferase Ubie_methyltran PF01209.18 KXH34725.1 - 0.073 12.4 0.0 0.54 9.6 0.0 2.1 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family DUF938 PF06080.12 KXH34725.1 - 0.096 12.4 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Abhydrolase_6 PF12697.7 KXH34726.1 - 1.5e-11 45.3 2.5 1.8e-11 45.1 2.5 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXH34726.1 - 1.3e-07 31.5 0.3 1.3e-05 25.0 0.3 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXH34726.1 - 0.0043 16.4 0.0 0.0059 15.9 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF1057 PF06342.12 KXH34726.1 - 0.066 12.2 0.0 0.094 11.7 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) Ndr PF03096.14 KXH34726.1 - 0.12 11.1 0.0 0.16 10.6 0.0 1.1 1 0 0 1 1 1 0 Ndr family Glyco_hydro_18 PF00704.28 KXH34727.1 - 1.5e-21 77.5 0.1 2.2e-21 76.9 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 KXH34727.1 - 7.6e-07 29.5 21.4 3e-06 27.6 21.4 2.0 1 0 0 1 1 1 1 Chitin recognition protein MSA-2c PF12238.8 KXH34727.1 - 3.4 7.6 4.3 6.3 6.7 4.3 1.4 1 0 0 1 1 1 0 Merozoite surface antigen 2c AF-4 PF05110.13 KXH34729.1 - 0.88 7.6 7.2 1.1 7.3 7.2 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein FAM199X PF15814.5 KXH34729.1 - 3.4 6.6 13.1 0.028 13.5 4.4 1.8 2 0 0 2 2 2 0 Protein family FAM199X COesterase PF00135.28 KXH34730.1 - 1.8e-74 251.5 0.0 4e-74 250.3 0.0 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXH34730.1 - 8.3e-07 29.1 0.1 2e-06 27.8 0.1 1.8 1 0 0 1 1 1 1 alpha/beta hydrolase fold WSC PF01822.19 KXH34731.1 - 2.2e-18 66.2 5.7 6.7e-18 64.7 5.7 1.9 1 0 0 1 1 1 1 WSC domain RhoGAP PF00620.27 KXH34775.1 - 5.1e-36 123.8 0.0 1.1e-35 122.7 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.22 KXH34775.1 - 1.6e-30 105.1 39.2 6.1e-11 42.4 4.6 4.9 5 0 0 5 5 5 4 LIM domain Desulfoferrod_N PF06397.12 KXH34775.1 - 0.85 9.3 2.8 0.59 9.8 0.1 2.2 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain dCMP_cyt_deam_1 PF00383.23 KXH34776.1 - 2.7e-18 65.7 0.0 3.8e-18 65.2 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KXH34776.1 - 1.2e-14 54.3 0.0 1.4e-14 54.0 0.0 1.1 1 0 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 KXH34776.1 - 0.012 15.7 0.9 0.08 13.0 0.9 2.0 1 1 0 1 1 1 0 Bd3614-like deaminase APOBEC2 PF18772.1 KXH34776.1 - 0.039 14.0 0.7 2.2 8.3 0.7 2.1 1 1 0 1 1 1 0 APOBEC2 NAD1 PF18778.1 KXH34776.1 - 0.095 12.8 0.8 2.9 8.0 0.3 2.1 1 1 1 2 2 2 0 Novel AID APOBEC clade 1 zf-HC5HC2H_2 PF13832.6 KXH34777.1 - 4.2e-20 71.9 0.5 4.2e-20 71.9 0.5 4.7 5 0 0 5 5 5 2 PHD-zinc-finger like domain BAH PF01426.18 KXH34777.1 - 2.3e-18 66.2 0.0 6.6e-18 64.7 0.0 1.8 1 0 0 1 1 1 1 BAH domain zf-HC5HC2H PF13771.6 KXH34777.1 - 5.4e-16 58.6 0.9 5.4e-16 58.6 0.9 5.2 4 1 0 4 4 4 1 PHD-like zinc-binding domain PHD PF00628.29 KXH34777.1 - 8.9e-11 41.5 56.7 1e-06 28.5 9.0 6.3 6 0 0 6 6 6 2 PHD-finger PHD_2 PF13831.6 KXH34777.1 - 2e-08 33.7 5.8 2e-08 33.7 5.8 5.1 7 0 0 7 7 7 2 PHD-finger C1_1 PF00130.22 KXH34777.1 - 0.0017 18.2 2.4 0.0017 18.2 2.4 6.2 6 1 1 7 7 7 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Myb_DNA-binding PF00249.31 KXH34777.1 - 0.0024 18.0 1.7 0.0031 17.7 0.1 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain C1_2 PF03107.16 KXH34777.1 - 0.025 14.9 0.5 0.025 14.9 0.5 6.7 8 0 0 8 8 8 0 C1 domain GATA PF00320.27 KXH34777.1 - 1.8 8.2 9.0 0.34 10.6 1.1 3.6 3 0 0 3 3 3 0 GATA zinc finger Bac_rhamnosid6H PF17389.2 KXH35025.1 - 1.2e-117 392.9 0.0 1.6e-117 392.6 0.0 1.1 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_N PF08531.10 KXH35025.1 - 1.6e-48 164.7 0.0 2.6e-48 164.1 0.0 1.3 1 0 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain Bac_rhamnosid PF05592.11 KXH35025.1 - 1.7e-25 89.0 0.0 3.4e-25 88.0 0.0 1.6 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase concanavalin-like domain Bac_rhamnosid_C PF17390.2 KXH35025.1 - 4.5e-17 61.6 0.0 1e-16 60.4 0.0 1.6 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain Sugar_tr PF00083.24 KXH35026.1 - 2.6e-89 300.2 28.8 3e-89 300.0 28.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH35026.1 - 1.5e-28 99.8 40.0 2.6e-27 95.7 30.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KXH35026.1 - 1.3e-05 23.9 4.3 1.3e-05 23.9 4.3 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF4231 PF14015.6 KXH35026.1 - 1.2 9.6 0.0 1.2 9.6 0.0 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF4231) Epimerase PF01370.21 KXH35027.1 - 1.6e-17 63.8 0.0 2e-17 63.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXH35027.1 - 7.2e-11 42.1 0.0 1e-10 41.6 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KXH35027.1 - 4.1e-09 35.8 0.0 5.4e-09 35.4 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KXH35027.1 - 1.3e-06 27.7 0.0 1.9e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 KXH35027.1 - 3.4e-05 23.2 0.2 0.11 11.7 0.3 2.4 2 1 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 KXH35027.1 - 0.015 15.2 0.0 0.025 14.4 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H-binding adh_short PF00106.25 KXH35027.1 - 0.072 12.5 0.0 0.16 11.4 0.0 1.6 1 1 0 1 1 1 0 short chain dehydrogenase Ldh_1_N PF00056.23 KXH35027.1 - 0.083 13.0 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain NmrA PF05368.13 KXH35029.1 - 1.6e-34 119.5 0.0 1.9e-34 119.3 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXH35029.1 - 1.2e-10 41.5 0.0 2.1e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KXH35029.1 - 0.00018 21.1 0.1 0.00028 20.4 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 KXH35029.1 - 0.02 15.2 0.0 0.031 14.5 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain 3Beta_HSD PF01073.19 KXH35029.1 - 0.021 13.8 0.0 0.029 13.4 0.0 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 KXH35029.1 - 0.18 11.7 0.1 0.29 11.0 0.1 1.3 1 0 0 1 1 1 0 KR domain PAP2_3 PF14378.6 KXH35030.1 - 3.5e-23 82.3 17.8 1.9e-18 66.8 3.2 2.7 3 0 0 3 3 3 2 PAP2 superfamily RtcB PF01139.17 KXH35030.1 - 0.012 14.9 0.0 0.017 14.3 0.0 1.2 1 0 0 1 1 1 0 tRNA-splicing ligase RtcB Fungal_trans PF04082.18 KXH35031.1 - 9e-10 38.0 0.1 2.2e-09 36.8 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain SKA2 PF16740.5 KXH35031.1 - 0.086 12.6 0.1 0.89 9.4 0.0 2.3 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 Zn_clus PF00172.18 KXH35032.1 - 2.2e-08 34.1 12.8 3.2e-08 33.6 12.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Vps39_2 PF10367.9 KXH35032.1 - 0.17 12.3 2.4 0.32 11.5 2.4 1.5 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 MGC-24 PF05283.11 KXH35032.1 - 0.33 11.4 5.1 0.66 10.4 5.1 1.5 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Glyco_hydro_3_C PF01915.22 KXH35033.1 - 1.3e-49 168.9 0.2 5.4e-49 166.9 0.2 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KXH35033.1 - 4.8e-38 131.3 0.0 8.4e-38 130.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KXH35033.1 - 2e-18 66.2 0.0 4.2e-18 65.2 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain ERG4_ERG24 PF01222.17 KXH35034.1 - 1.6e-165 551.1 0.4 1.8e-165 550.9 0.4 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 KXH35034.1 - 0.00022 20.9 1.0 0.00044 19.9 0.2 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) Man-6-P_recep PF02157.15 KXH35035.1 - 8.5e-17 61.1 0.0 4e-16 58.9 0.0 1.8 2 0 0 2 2 2 1 Mannose-6-phosphate receptor ATG27 PF09451.10 KXH35035.1 - 3.8e-14 53.2 0.0 5.8e-14 52.6 0.0 1.4 1 1 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.18 KXH35035.1 - 3.1e-09 37.0 0.2 3.5e-05 23.9 0.0 2.3 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat Aldo_ket_red PF00248.21 KXH35036.1 - 1.4e-43 149.2 0.0 6.7e-32 110.9 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family HET PF06985.11 KXH35037.1 - 2e-14 54.2 6.0 3.9e-13 50.0 6.0 2.2 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Amino_oxidase PF01593.24 KXH35038.1 - 1.6e-38 133.1 0.0 2.4e-38 132.6 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KXH35038.1 - 6.7e-09 35.9 0.0 2.1e-08 34.2 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain bZIP_1 PF00170.21 KXH35038.1 - 0.00016 21.7 8.4 0.00033 20.7 8.4 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KXH35038.1 - 0.00027 20.9 11.2 0.00052 20.0 11.2 1.5 1 0 0 1 1 1 1 Basic region leucine zipper Pyr_redox_3 PF13738.6 KXH35038.1 - 0.0015 17.8 0.1 0.0049 16.2 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DUF641 PF04859.12 KXH35038.1 - 0.0055 17.0 3.2 0.068 13.5 2.4 2.2 2 0 0 2 2 2 1 Plant protein of unknown function (DUF641) FAD_binding_3 PF01494.19 KXH35038.1 - 0.018 14.3 0.3 0.032 13.5 0.3 1.4 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 KXH35038.1 - 0.034 12.9 0.3 0.063 12.0 0.3 1.4 1 0 0 1 1 1 0 HI0933-like protein MCPVI PF02993.14 KXH35038.1 - 0.037 13.8 1.0 0.068 13.0 1.0 1.3 1 0 0 1 1 1 0 Minor capsid protein VI Mcm10 PF09332.11 KXH35038.1 - 0.048 13.1 1.4 0.066 12.6 1.4 1.1 1 0 0 1 1 1 0 Mcm10 replication factor bZIP_Maf PF03131.17 KXH35038.1 - 0.13 12.8 5.8 0.26 11.8 5.8 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor ATG16 PF08614.11 KXH35038.1 - 0.21 11.8 5.9 0.34 11.1 5.9 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) SlyX PF04102.12 KXH35038.1 - 0.41 11.3 2.7 1 10.1 2.7 1.7 1 0 0 1 1 1 0 SlyX NmrA PF05368.13 KXH35039.1 - 8.3e-21 74.6 0.3 1.4e-20 73.8 0.3 1.3 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXH35039.1 - 5.5e-19 68.8 0.0 9.8e-19 68.0 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KXH35039.1 - 7.9e-07 29.4 2.4 0.0038 17.5 0.2 2.2 2 0 0 2 2 2 2 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 KXH35039.1 - 2.9e-06 27.0 0.2 4.5e-06 26.3 0.2 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.17 KXH35039.1 - 0.00018 22.0 1.0 0.00035 21.1 0.2 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent adh_short PF00106.25 KXH35039.1 - 0.00069 19.1 1.5 0.00074 19.0 0.3 1.6 2 0 0 2 2 2 1 short chain dehydrogenase CoA_binding_2 PF13380.6 KXH35039.1 - 0.0066 16.9 0.7 0.54 10.8 0.2 2.3 2 0 0 2 2 2 1 CoA binding domain RmlD_sub_bind PF04321.17 KXH35039.1 - 0.0088 15.2 0.1 0.013 14.6 0.1 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain LpxI_N PF17930.1 KXH35039.1 - 0.0089 15.9 0.3 0.031 14.2 0.1 1.9 2 0 0 2 2 2 1 LpxI N-terminal domain NAD_binding_2 PF03446.15 KXH35039.1 - 0.0094 16.1 0.7 0.017 15.3 0.2 1.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Semialdhyde_dh PF01118.24 KXH35039.1 - 0.014 15.8 2.1 0.021 15.3 0.8 1.9 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 KXH35039.1 - 0.032 14.7 0.8 0.076 13.5 0.8 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding 3Beta_HSD PF01073.19 KXH35039.1 - 0.035 13.1 0.2 0.056 12.5 0.2 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family 3HCDH_N PF02737.18 KXH35039.1 - 0.091 12.6 2.5 0.076 12.9 0.6 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DapB_N PF01113.20 KXH35039.1 - 0.12 12.6 2.5 0.14 12.3 0.6 2.2 2 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus THF_DHG_CYH_C PF02882.19 KXH35039.1 - 4.8 6.5 5.7 2.5 7.4 1.0 2.7 3 2 0 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Dioxygenase_C PF00775.21 KXH35040.1 - 0.00018 21.0 0.0 0.00055 19.4 0.0 1.9 1 1 0 1 1 1 1 Dioxygenase MAPEG PF01124.18 KXH35042.1 - 9.7e-21 74.0 0.1 1.1e-20 73.8 0.1 1.0 1 0 0 1 1 1 1 MAPEG family Serglycin PF04360.12 KXH35044.1 - 0.018 15.0 1.0 0.021 14.8 1.0 1.2 1 0 0 1 1 1 0 Serglycin MFS_1 PF07690.16 KXH35046.1 - 3.6e-38 131.4 36.5 3.6e-38 131.4 36.5 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 KXH35046.1 - 0.0005 18.6 0.6 0.0005 18.6 0.6 1.7 1 1 1 2 2 2 2 Transmembrane secretion effector TRI12 PF06609.13 KXH35046.1 - 0.0006 18.4 6.9 0.0006 18.4 6.9 1.9 2 1 1 3 3 3 1 Fungal trichothecene efflux pump (TRI12) AA_permease_2 PF13520.6 KXH35047.1 - 6.5e-90 302.0 31.4 8.1e-90 301.7 31.4 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXH35047.1 - 1.6e-20 73.2 28.1 2.4e-20 72.6 28.1 1.2 1 0 0 1 1 1 1 Amino acid permease SirB PF04247.12 KXH35047.1 - 0.068 13.3 2.0 0.16 12.1 0.1 2.6 2 0 0 2 2 2 0 Invasion gene expression up-regulator, SirB CorA PF01544.18 KXH35048.1 - 0.023 14.0 0.6 0.023 14.0 0.6 1.9 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein MFS_1 PF07690.16 KXH35049.1 - 1e-14 54.2 50.5 1e-14 54.2 50.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Asparaginase_II PF06089.12 KXH35050.1 - 2.2e-118 395.0 0.5 2.5e-118 394.8 0.5 1.0 1 0 0 1 1 1 1 L-asparaginase II GFA PF04828.14 KXH35051.1 - 6.2e-22 77.8 0.6 9.7e-22 77.1 0.6 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Rpr2 PF04032.16 KXH35051.1 - 0.043 14.1 2.7 0.54 10.6 0.0 2.3 2 0 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Peptidase_C32 PF05411.12 KXH35051.1 - 0.15 12.0 0.0 6.4 6.7 0.0 2.2 1 1 1 2 2 2 0 Equine arteritis virus putative proteinase NOB1_Zn_bind PF08772.11 KXH35051.1 - 0.39 10.9 4.3 3.7 7.8 0.0 2.5 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like Zn_clus PF00172.18 KXH35052.1 - 1e-07 31.9 7.8 2e-07 31.0 7.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KXH35052.1 - 0.005 15.7 0.9 0.0062 15.4 0.2 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Roughex PF06020.11 KXH35052.1 - 0.12 11.5 0.3 0.19 10.8 0.3 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Zn_clus PF00172.18 KXH35053.1 - 1.7e-07 31.3 10.6 2.5e-07 30.7 10.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MgtE_N PF03448.17 KXH35053.1 - 0.0034 18.0 0.2 0.037 14.6 0.0 2.2 2 0 0 2 2 2 1 MgtE intracellular N domain BCA_ABC_TP_C PF12399.8 KXH35053.1 - 0.15 12.0 0.2 0.46 10.5 0.0 2.0 2 0 0 2 2 2 0 Branched-chain amino acid ATP-binding cassette transporter Rep_fac-A_C PF08646.10 KXH35053.1 - 9 6.0 7.1 3.1 7.5 3.8 1.9 2 0 0 2 2 2 0 Replication factor-A C terminal domain 2OG-FeII_Oxy_3 PF13640.6 KXH35055.1 - 2.2e-10 41.3 0.2 3.8e-10 40.5 0.2 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily HSP70 PF00012.20 KXH35060.1 - 0.62 8.2 2.8 0.95 7.6 2.8 1.2 1 0 0 1 1 1 0 Hsp70 protein NADH_dehy_S2_C PF06444.11 KXH35061.1 - 0.13 12.8 1.3 0.47 11.0 1.3 1.9 1 0 0 1 1 1 0 NADH dehydrogenase subunit 2 C-terminus Pkinase PF00069.25 KXH35062.1 - 5.3e-51 173.5 0.0 7.3e-51 173.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXH35062.1 - 9.9e-27 93.8 0.3 1.3e-25 90.2 0.2 2.3 2 1 0 2 2 2 1 Protein tyrosine kinase FTA2 PF13095.6 KXH35062.1 - 0.032 13.9 0.4 7.5 6.1 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 KXH35062.1 - 0.041 12.7 1.7 0.043 12.6 0.0 1.8 2 0 0 2 2 2 0 Fungal protein kinase Kinase-like PF14531.6 KXH35062.1 - 0.14 11.4 0.0 0.28 10.4 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Autophagy_N PF03986.13 KXH35063.1 - 6.3e-47 159.0 0.6 1.2e-46 158.1 0.0 1.7 2 0 0 2 2 2 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.15 KXH35063.1 - 2.6e-16 59.9 0.1 5.2e-16 59.0 0.1 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_C PF10381.9 KXH35063.1 - 5.4e-16 57.8 0.6 9.8e-16 57.0 0.6 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal zf-CCCH PF00642.24 KXH35064.1 - 6.9e-08 32.2 2.4 1.3e-07 31.3 2.4 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.6 KXH35064.1 - 2e-07 30.8 5.2 3.5e-07 30.0 5.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXH35064.1 - 6.5e-07 29.3 6.7 1.3e-06 28.3 6.7 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KXH35064.1 - 6.8e-07 29.2 7.5 1.1e-06 28.4 7.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KXH35064.1 - 7.3e-07 29.0 9.1 1.3e-06 28.2 9.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXH35064.1 - 4.4e-06 26.4 8.0 8.3e-06 25.5 8.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf_CCCH_4 PF18345.1 KXH35064.1 - 2.8e-05 24.0 6.4 5.4e-05 23.1 6.4 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-RING_2 PF13639.6 KXH35064.1 - 4.7e-05 23.6 6.9 8.7e-05 22.8 6.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_10 PF16685.5 KXH35064.1 - 0.00016 21.8 2.4 0.00016 21.8 2.4 1.6 2 0 0 2 2 1 1 zinc RING finger of MSL2 zf-CCCH_4 PF18044.1 KXH35064.1 - 0.00018 21.2 2.6 0.00037 20.2 2.6 1.6 1 0 0 1 1 1 1 CCCH-type zinc finger Prok-RING_4 PF14447.6 KXH35064.1 - 0.0042 16.9 5.3 0.0079 16.0 5.3 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KXH35064.1 - 0.04 14.1 8.1 0.1 12.8 8.1 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-CCCH_2 PF14608.6 KXH35064.1 - 0.19 12.2 2.9 0.37 11.3 2.9 1.5 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger Harakiri PF15196.6 KXH35064.1 - 0.25 11.8 3.2 0.22 12.0 1.3 1.9 2 0 0 2 2 2 0 Activator of apoptosis harakiri Mcp5_PH PF12814.7 KXH35065.1 - 5e-45 152.6 0.0 9.3e-45 151.7 0.0 1.5 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology PH PF00169.29 KXH35065.1 - 8.2e-06 26.3 0.0 3.8e-05 24.1 0.0 2.1 2 0 0 2 2 2 1 PH domain Dynein_IC2 PF11540.8 KXH35065.1 - 0.43 10.6 6.8 95 3.1 0.0 6.3 7 0 0 7 7 7 0 Cytoplasmic dynein 1 intermediate chain 2 MMM1 PF10296.9 KXH35066.1 - 3.6e-06 26.3 0.0 3.6e-06 26.3 0.0 2.0 3 0 0 3 3 3 1 Maintenance of mitochondrial morphology protein 1 Edc3_linker PF16598.5 KXH35066.1 - 8.9 7.0 10.4 5 7.8 5.5 3.0 2 1 0 2 2 2 0 Linker region of enhancer of mRNA-decapping protein 3 DNA_pol_B PF00136.21 KXH35067.1 - 7.5e-104 348.0 0.0 1.2e-103 347.3 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 KXH35067.1 - 7.1e-22 78.0 0.1 3.9e-11 42.7 0.0 2.5 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 KXH35067.1 - 1.4e-16 60.7 5.7 1.4e-16 60.7 5.7 2.2 2 0 0 2 2 2 1 C4-type zinc-finger of DNA polymerase delta XkdW PF09636.10 KXH35067.1 - 0.076 13.1 0.2 0.21 11.7 0.2 1.8 1 0 0 1 1 1 0 XkdW protein Slu7 PF11708.8 KXH35068.1 - 6.1e-75 252.4 21.7 6.1e-75 252.4 21.7 2.8 3 1 0 3 3 3 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.6 KXH35068.1 - 0.028 14.1 0.5 0.052 13.3 0.5 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 KXH35068.1 - 0.11 12.7 2.7 0.21 11.7 2.7 1.4 1 0 0 1 1 1 0 Zinc knuckle S4 PF01479.25 KXH35069.1 - 2.4e-12 46.4 0.9 2.4e-12 46.4 0.9 2.5 3 0 0 3 3 3 1 S4 domain Ribosomal_S4 PF00163.19 KXH35069.1 - 1e-05 26.4 0.1 1.8e-05 25.6 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain Ribosomal_L21e PF01157.18 KXH35070.1 - 2e-47 159.2 4.6 3.2e-47 158.5 4.6 1.3 1 0 0 1 1 1 1 Ribosomal protein L21e DUF5486 PF17588.2 KXH35070.1 - 0.011 15.6 1.8 0.15 12.0 0.1 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5486) ANTH PF07651.16 KXH35071.1 - 5.8e-82 274.8 0.0 5.8e-82 274.8 0.0 2.5 3 0 0 3 3 3 1 ANTH domain I_LWEQ PF01608.17 KXH35071.1 - 4.7e-55 186.0 9.7 4.7e-55 186.0 9.7 5.9 4 1 1 5 5 5 2 I/LWEQ domain TcdB_N PF12918.7 KXH35071.1 - 3.4 8.0 7.1 0.23 11.8 0.4 2.8 3 0 0 3 3 3 0 TcdB toxin N-terminal helical domain HMG_box PF00505.19 KXH35073.1 - 5.3e-22 78.0 1.3 8.6e-22 77.3 1.3 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KXH35073.1 - 4.2e-08 33.7 0.5 6.9e-08 33.0 0.5 1.3 1 0 0 1 1 1 1 HMG-box domain MATalpha_HMGbox PF04769.12 KXH35073.1 - 4.8e-05 22.8 0.0 6.7e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 HMG-box NAAA-beta PF15508.6 KXH35073.1 - 0.11 12.8 0.7 2.2 8.6 0.1 2.8 3 0 0 3 3 3 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase TMEM171 PF15471.6 KXH35073.1 - 0.18 10.8 0.1 0.23 10.4 0.1 1.1 1 0 0 1 1 1 0 Transmembrane protein family 171 GOLGA2L5 PF15070.6 KXH35179.1 - 0.13 10.9 0.0 0.21 10.2 0.0 1.2 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 NmrA PF05368.13 KXH35180.1 - 3.2e-15 56.3 0.3 4.6e-15 55.8 0.3 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXH35180.1 - 7.7e-12 45.5 0.2 5.5e-11 42.7 0.2 2.0 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KXH35180.1 - 8.8e-10 38.4 1.2 4.6e-08 32.8 1.2 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KXH35180.1 - 0.00068 19.6 0.1 0.0011 18.9 0.1 1.4 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.20 KXH35180.1 - 0.0011 19.1 0.2 0.0045 17.1 0.1 1.8 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 KXH35180.1 - 0.005 17.1 0.4 0.0091 16.3 0.4 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain GDP_Man_Dehyd PF16363.5 KXH35180.1 - 0.0068 15.8 1.1 0.26 10.7 0.8 2.4 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase F420_oxidored PF03807.17 KXH35180.1 - 0.038 14.6 1.4 0.89 10.2 0.4 2.8 2 1 1 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent Polysacc_synt_2 PF02719.15 KXH35180.1 - 0.16 11.1 1.0 0.43 9.7 1.0 1.7 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein SAPS PF04499.15 KXH35181.1 - 0.023 13.5 0.1 0.028 13.2 0.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein ProQ PF04352.13 KXH35181.1 - 0.034 14.0 0.5 0.065 13.1 0.0 1.7 2 0 0 2 2 2 0 ProQ/FINO family FAD_binding_4 PF01565.23 KXH35183.1 - 2.3e-18 66.3 1.6 4.1e-18 65.5 1.6 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KXH35183.1 - 0.0058 16.7 1.1 0.018 15.1 0.7 1.9 2 0 0 2 2 2 1 Berberine and berberine like LysM PF01476.20 KXH35185.1 - 1e-07 31.9 0.1 1.3e-07 31.5 0.1 1.1 1 0 0 1 1 1 1 LysM domain Podoplanin PF05808.11 KXH35186.1 - 0.0033 17.6 0.4 0.0059 16.7 0.4 1.4 1 0 0 1 1 1 1 Podoplanin DUF4901 PF16244.5 KXH35187.1 - 0.0072 15.7 0.0 0.058 12.7 0.0 2.2 3 0 0 3 3 3 1 Domain of unknown function (DUF4901) Fijivirus_P9-2 PF06837.11 KXH35187.1 - 0.16 11.4 2.1 0.23 10.9 1.2 1.8 2 1 0 2 2 2 0 Fijivirus P9-2 protein DUF1180 PF06679.12 KXH35188.1 - 0.015 15.7 2.8 0.015 15.7 2.8 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1180) DUF1547 PF07577.11 KXH35188.1 - 1.8 9.0 6.4 27 5.2 0.3 3.8 3 1 0 3 3 3 0 Domain of Unknown Function (DUF1547) Catalase PF00199.19 KXH35189.1 - 3.7e-172 572.7 0.5 5.9e-172 572.1 0.5 1.3 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 KXH35189.1 - 8.8e-21 73.9 0.1 1.8e-20 72.9 0.1 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive Catalase_C PF18011.1 KXH35189.1 - 4.6e-08 32.9 1.1 1.6e-07 31.1 0.6 2.2 2 1 0 2 2 2 1 C-terminal domain found in long catalases DJ-1_PfpI PF01965.24 KXH35189.1 - 1.3e-05 25.1 0.0 2.2e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family NFACT-R_1 PF05670.13 KXH35190.1 - 4.5e-27 94.8 0.0 5.3e-25 88.2 0.0 2.3 1 1 0 1 1 1 1 NFACT protein RNA binding domain HeLo PF14479.6 KXH35191.1 - 1.5e-05 24.9 7.5 0.016 15.0 0.1 3.0 2 1 1 3 3 3 2 Prion-inhibition and propagation DUF842 PF05811.13 KXH35192.1 - 0.0013 18.4 2.6 0.042 13.5 0.2 4.1 3 1 0 3 3 3 1 Eukaryotic protein of unknown function (DUF842) DUF4085 PF13315.6 KXH35192.1 - 0.046 13.3 2.4 0.095 12.3 1.8 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF4085) Tup_N PF08581.10 KXH35192.1 - 0.13 12.5 1.3 1.5 9.2 0.1 3.0 2 1 1 3 3 3 0 Tup N-terminal RINGv PF12906.7 KXH35193.1 - 5.8e-17 61.5 9.0 9.5e-17 60.9 9.0 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 KXH35193.1 - 0.0053 17.1 8.6 0.0096 16.2 8.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-ANAPC11 PF12861.7 KXH35193.1 - 0.39 10.8 2.0 0.95 9.6 2.0 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zf_RING PF16744.5 KXH35193.1 - 1.4 9.1 3.1 2.8 8.1 3.1 1.4 1 0 0 1 1 1 0 KIAA1045 RING finger zf-C3HC4_3 PF13920.6 KXH35193.1 - 3.3 7.7 5.5 6.2 6.8 5.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 KXH35193.1 - 4.1 7.7 5.3 7.7 6.8 5.3 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.6 KXH35193.1 - 4.2 7.2 7.3 7.5 6.4 7.3 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Alpha_GJ PF03229.13 KXH35194.1 - 3.4 8.2 20.3 7.2 7.2 14.4 2.3 2 0 0 2 2 2 0 Alphavirus glycoprotein J DUF4360 PF14273.6 KXH35243.1 - 5.3e-30 104.6 0.3 6.4e-30 104.3 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DUF3405 PF11885.8 KXH35244.1 - 1.1e-189 631.4 0.2 1.1e-189 631.4 0.2 2.3 2 0 0 2 2 1 1 Protein of unknown function (DUF3405) UPF0242 PF06785.11 KXH35244.1 - 0.012 15.7 14.0 0.02 15.0 14.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DDHD PF02862.17 KXH35244.1 - 0.055 13.6 3.5 0.091 12.9 3.5 1.3 1 0 0 1 1 1 0 DDHD domain V_ATPase_I PF01496.19 KXH35244.1 - 0.085 10.8 12.8 0.12 10.3 12.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RR_TM4-6 PF06459.12 KXH35244.1 - 0.28 11.0 18.2 0.46 10.3 18.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 APG6_N PF17675.1 KXH35244.1 - 0.31 11.5 39.3 0.54 10.8 39.3 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region PA26 PF04636.13 KXH35244.1 - 0.42 9.5 6.8 0.65 8.9 6.8 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Asp-B-Hydro_N PF05279.11 KXH35244.1 - 0.44 10.6 19.3 0.69 9.9 19.3 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Fmp27_WPPW PF10359.9 KXH35244.1 - 0.57 9.0 17.2 1.2 7.9 13.0 2.2 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain DUF3450 PF11932.8 KXH35244.1 - 0.83 8.9 16.2 1.8 7.8 16.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) YabA PF06156.13 KXH35244.1 - 1.5 9.5 16.2 3.1 8.5 16.2 1.5 1 0 0 1 1 1 0 Initiation control protein YabA HAUS-augmin3 PF14932.6 KXH35244.1 - 1.9 8.0 26.1 3.4 7.2 26.1 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF966 PF06136.13 KXH35244.1 - 3.1 7.4 13.5 4.7 6.8 13.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Neur_chan_memb PF02932.16 KXH35244.1 - 4.9 7.1 4.6 7.6 6.5 4.6 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Vfa1 PF08432.10 KXH35244.1 - 5 7.4 21.9 8.3 6.7 21.9 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Borrelia_P83 PF05262.11 KXH35244.1 - 5.1 5.5 23.0 7.4 4.9 23.0 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Rgp1 PF08737.10 KXH35244.1 - 5.3 6.1 8.3 7.8 5.5 8.3 1.2 1 0 0 1 1 1 0 Rgp1 Exonuc_VII_L PF02601.15 KXH35244.1 - 7.1 6.1 13.8 8.7 5.8 11.8 1.9 2 0 0 2 2 2 0 Exonuclease VII, large subunit YdfA_immunity PF12127.8 KXH35244.1 - 7.5 5.5 7.0 11 4.9 7.0 1.1 1 0 0 1 1 1 0 SigmaW regulon antibacterial PXA PF02194.15 KXH35245.1 - 1.2e-53 181.7 0.8 5.8e-53 179.6 0.8 2.3 1 0 0 1 1 1 1 PXA domain Nexin_C PF08628.12 KXH35245.1 - 3e-30 105.1 0.1 1e-29 103.3 0.1 2.0 1 0 0 1 1 1 1 Sorting nexin C terminal PX PF00787.24 KXH35245.1 - 4.2e-21 75.0 0.5 1.3e-20 73.5 0.5 1.9 1 0 0 1 1 1 1 PX domain RGS PF00615.19 KXH35245.1 - 1.6e-11 44.5 0.0 5.3e-11 42.8 0.0 2.0 1 0 0 1 1 1 1 Regulator of G protein signaling domain Methyltransf_4 PF02390.17 KXH35246.1 - 5.1e-55 185.6 0.0 6.7e-55 185.2 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_32 PF13679.6 KXH35246.1 - 0.00022 21.2 0.0 0.00041 20.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH35246.1 - 0.00023 21.8 0.0 0.00039 21.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXH35246.1 - 0.0015 18.1 0.0 0.0039 16.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 KXH35246.1 - 0.0053 17.5 0.0 0.015 16.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH35246.1 - 0.0055 16.5 0.0 0.0067 16.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KXH35246.1 - 0.0083 15.9 0.0 0.012 15.4 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.20 KXH35246.1 - 0.027 13.6 0.0 0.034 13.2 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_11 PF08241.12 KXH35246.1 - 0.047 14.3 0.1 0.14 12.8 0.0 2.0 2 1 0 2 2 1 0 Methyltransferase domain DUF4191 PF13829.6 KXH35246.1 - 0.058 12.7 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) Ubie_methyltran PF01209.18 KXH35246.1 - 0.1 11.9 0.0 0.18 11.1 0.0 1.4 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family TMEM171 PF15471.6 KXH35247.1 - 3.2 6.7 6.5 1.1 8.2 0.4 2.0 1 1 1 2 2 2 0 Transmembrane protein family 171 DUF4078 PF13300.6 KXH35248.1 - 1.6e-28 98.8 20.0 1.6e-28 98.8 20.0 2.6 4 0 0 4 4 4 1 Domain of unknown function (DUF4078) MRP-63 PF14978.6 KXH35248.1 - 0.39 11.4 0.0 0.39 11.4 0.0 2.8 2 1 0 2 2 2 0 Mitochondrial ribosome protein 63 Cwf_Cwc_15 PF04889.12 KXH35248.1 - 1.4 8.6 34.8 0.13 12.0 12.0 2.1 1 1 1 2 2 2 0 Cwf15/Cwc15 cell cycle control protein VIR_N PF15912.5 KXH35248.1 - 9.7 5.7 16.8 9 5.8 1.1 2.2 2 0 0 2 2 2 0 Virilizer, N-terminal DUF2207 PF09972.9 KXH35249.1 - 0.14 10.9 0.0 0.2 10.4 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Spt20 PF12090.8 KXH35249.1 - 2.3 7.8 7.9 4.6 6.8 7.9 1.4 1 0 0 1 1 1 0 Spt20 family AF-4 PF05110.13 KXH35250.1 - 2.2 6.2 11.3 2.9 5.8 11.3 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Apt1 PF10351.9 KXH35250.1 - 4 6.2 6.0 5 5.9 6.0 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain BCS1_N PF08740.11 KXH35251.1 - 1.2e-57 194.9 3.8 1.2e-57 194.9 3.8 2.7 2 1 0 2 2 1 1 BCS1 N terminal AAA PF00004.29 KXH35251.1 - 7.5e-17 62.0 0.0 9.6e-08 32.5 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KXH35251.1 - 0.0028 17.7 0.0 0.017 15.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KXH35251.1 - 0.0033 17.2 0.0 0.0069 16.1 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_11 PF13086.6 KXH35251.1 - 0.0048 16.7 15.9 4.2 7.1 16.2 2.4 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 KXH35251.1 - 0.03 13.9 0.4 0.067 12.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KXH35251.1 - 0.045 14.1 0.1 0.045 14.1 0.1 2.6 1 1 1 2 2 2 0 AAA ATPase domain MCM_bind PF09739.9 KXH35251.1 - 0.045 12.2 17.5 0.07 11.6 17.5 1.3 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor AAA_29 PF13555.6 KXH35251.1 - 0.086 12.6 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.6 KXH35251.1 - 0.12 12.9 0.1 0.12 12.9 0.1 3.7 2 2 1 3 3 2 0 AAA domain DUF2178 PF09946.9 KXH35251.1 - 0.16 12.1 0.1 0.33 11.2 0.1 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) PCM1_C PF15717.5 KXH35251.1 - 0.59 8.8 24.8 0.97 8.1 24.8 1.3 1 0 0 1 1 1 0 Pericentriolar material 1 C terminus PAP1 PF08601.10 KXH35251.1 - 0.76 9.4 17.4 1.2 8.8 17.4 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 AAA_23 PF13476.6 KXH35251.1 - 0.99 9.9 18.8 1.7 9.1 14.4 2.6 2 0 0 2 2 2 0 AAA domain LRIF1 PF15741.5 KXH35251.1 - 2.2 6.7 22.7 3.2 6.2 22.7 1.2 1 0 0 1 1 1 0 Ligand-dependent nuclear receptor-interacting factor 1 DUF572 PF04502.13 KXH35251.1 - 2.4 7.7 28.4 4.8 6.7 28.4 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF572) Rrn6 PF10214.9 KXH35251.1 - 4.8 5.5 14.4 8.9 4.7 14.4 1.4 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DUF4569 PF15133.6 KXH35251.1 - 5.8 6.5 13.8 32 4.1 14.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4569) SAPS PF04499.15 KXH35251.1 - 6.1 5.5 19.2 9.5 4.9 19.2 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein GAGA_bind PF06217.12 KXH35251.1 - 7.1 6.8 19.6 16 5.7 19.6 1.6 1 0 0 1 1 1 0 GAGA binding protein-like family HMG_CoA_synt_C PF08540.10 KXH35252.1 - 1.1e-98 330.4 0.8 1.9e-98 329.6 0.8 1.4 1 1 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 KXH35252.1 - 4.1e-94 313.3 0.5 6e-94 312.8 0.5 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal FAD_binding_4 PF01565.23 KXH35253.1 - 3e-14 52.9 0.0 5.2e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Abhydrolase_3 PF07859.13 KXH35254.1 - 1.2e-48 165.8 0.0 3.5e-48 164.3 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KXH35254.1 - 3e-05 23.1 0.1 0.00012 21.1 0.1 1.9 1 1 0 1 1 1 1 Steryl acetyl hydrolase Phage_base_V PF04717.12 KXH35254.1 - 0.19 11.6 0.0 0.35 10.8 0.0 1.3 1 0 0 1 1 1 0 Type VI secretion system, phage-baseplate injector Baculo_LEF5_C PF11792.8 KXH35257.1 - 0.18 11.5 0.2 0.46 10.2 0.2 1.6 1 0 0 1 1 1 0 Baculoviridae late expression factor 5 C-terminal domain PIG-H PF10181.9 KXH35258.1 - 1.1e-26 92.5 0.2 1.7e-26 91.9 0.2 1.3 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component PseudoU_synth_1 PF01416.20 KXH35259.1 - 1.1e-31 109.4 0.0 7.8e-31 106.7 0.0 2.2 2 0 0 2 2 2 1 tRNA pseudouridine synthase Osteoregulin PF07175.11 KXH35259.1 - 0.14 12.3 1.3 0.2 11.8 0.1 1.8 2 0 0 2 2 2 0 Osteoregulin DUF2201_N PF13203.6 KXH35259.1 - 1.8 8.1 11.0 0.42 10.2 0.6 2.6 3 0 0 3 3 3 0 Putative metallopeptidase domain Ras PF00071.22 KXH35260.1 - 7.9e-20 71.1 0.0 1.2e-19 70.5 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXH35260.1 - 2.7e-05 24.4 0.0 0.00012 22.3 0.0 2.0 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXH35260.1 - 0.0032 16.9 0.0 0.6 9.6 0.0 2.1 2 0 0 2 2 2 2 ADP-ribosylation factor family AAA_24 PF13479.6 KXH35260.1 - 0.072 12.8 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.20 KXH35260.1 - 0.076 12.2 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit SRPRB PF09439.10 KXH35260.1 - 0.086 12.3 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_25 PF13481.6 KXH35260.1 - 0.18 11.3 0.1 0.56 9.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain RNA_pol_Rpb4 PF03874.16 KXH35261.1 - 1.7e-23 83.3 0.0 2e-23 83.1 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 Polysacc_deac_2 PF04748.13 KXH35261.1 - 0.02 14.1 0.0 0.036 13.3 0.0 1.4 1 1 0 1 1 1 0 Divergent polysaccharide deacetylase DUF3926 PF13080.6 KXH35261.1 - 0.074 13.0 0.2 0.18 11.8 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3926) Pribosyl_synth PF14572.6 KXH35262.1 - 9.2e-43 146.4 2.0 6.3e-37 127.4 0.5 2.4 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 KXH35262.1 - 3.4e-32 110.8 0.0 7.6e-32 109.7 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 KXH35262.1 - 1e-17 64.1 0.6 1.9e-17 63.2 0.1 1.6 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KXH35262.1 - 0.0013 18.2 0.1 0.0021 17.6 0.1 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase DUF5572 PF17733.1 KXH35263.1 - 1.4e-18 66.4 0.4 3.6e-18 65.1 0.4 1.8 1 0 0 1 1 1 1 Family of unknown function (DUF5572) GET2 PF08690.10 KXH35263.1 - 0.04 13.6 0.9 0.054 13.2 0.9 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 Med3 PF11593.8 KXH35263.1 - 8.5 5.4 11.1 11 5.1 11.1 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal PUF PF00806.19 KXH35264.1 - 5.4e-39 129.7 0.8 3.3e-06 26.5 0.0 8.7 9 0 0 9 9 9 7 Pumilio-family RNA binding repeat RasGEF PF00617.19 KXH35264.1 - 0.11 12.7 0.3 0.37 11.0 0.0 2.1 2 0 0 2 2 2 0 RasGEF domain MRP-S33 PF08293.11 KXH35265.1 - 6.6e-32 109.6 0.0 8.6e-32 109.2 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 Cupin_4 PF08007.12 KXH35265.1 - 0.094 12.2 0.0 0.59 9.6 0.0 1.8 2 0 0 2 2 2 0 Cupin superfamily protein Ribonuclease_3 PF00636.26 KXH35266.1 - 5.3e-13 49.5 0.0 1.4e-12 48.2 0.0 1.8 1 0 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KXH35266.1 - 1.3e-08 35.1 0.0 4.8e-08 33.2 0.0 2.0 2 0 0 2 2 2 1 Ribonuclease-III-like dsrm PF00035.26 KXH35266.1 - 0.00033 21.3 0.1 0.00086 20.0 0.1 1.7 1 0 0 1 1 1 1 Double-stranded RNA binding motif BCL9 PF11502.8 KXH35266.1 - 0.058 13.2 0.1 0.12 12.1 0.1 1.6 1 0 0 1 1 1 0 B-cell lymphoma 9 protein Molybdopterin PF00384.22 KXH35268.1 - 9.3e-74 248.9 0.0 7.3e-72 242.7 0.0 2.1 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Fer2_4 PF13510.6 KXH35268.1 - 3.7e-21 75.0 0.3 8.7e-21 73.8 0.3 1.7 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH_dhqG_C PF09326.11 KXH35268.1 - 2.3e-19 69.8 0.0 8.3e-19 68.0 0.0 2.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit G, C-terminal NADH-G_4Fe-4S_3 PF10588.9 KXH35268.1 - 7.9e-17 60.5 0.2 7.9e-17 60.5 0.2 2.2 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2 PF00111.27 KXH35268.1 - 1e-08 35.0 0.8 1e-08 35.0 0.8 2.2 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Lyx_isomer PF07385.12 KXH35268.1 - 0.014 14.7 0.0 0.034 13.4 0.0 1.6 2 0 0 2 2 2 0 D-lyxose isomerase TPP_enzyme_M PF00205.22 KXH35268.1 - 0.021 14.6 0.0 0.21 11.3 0.0 2.2 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Fer4 PF00037.27 KXH35268.1 - 0.12 12.2 1.1 3.5 7.6 0.3 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain UPF0061 PF02696.14 KXH35269.1 - 8e-125 417.2 0.0 1e-124 416.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family Aldo_ket_red PF00248.21 KXH35270.1 - 2.5e-39 135.2 0.0 5.2e-33 114.5 0.0 2.0 2 0 0 2 2 2 2 Aldo/keto reductase family Toprim_Crpt PF13342.6 KXH35270.1 - 0.033 14.2 0.0 0.087 12.8 0.0 1.7 2 0 0 2 2 2 0 C-terminal repeat of topoisomerase XRCC4 PF06632.12 KXH35271.1 - 1.1e-11 44.2 17.0 2.3e-11 43.2 17.0 1.4 1 1 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 SWIRM-assoc_2 PF16496.5 KXH35271.1 - 1.9 7.3 11.7 2.8 6.7 11.7 1.3 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal NOA36 PF06524.12 KXH35271.1 - 3 7.1 5.9 4.7 6.5 5.9 1.3 1 0 0 1 1 1 0 NOA36 protein Methyltr_RsmB-F PF01189.17 KXH35273.1 - 4.2e-76 255.1 0.0 6.9e-76 254.3 0.0 1.4 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 KXH35273.1 - 6.4e-08 33.0 0.0 1.9e-07 31.5 0.0 1.8 1 0 0 1 1 1 1 N-terminal domain of 16S rRNA methyltransferase RsmF Methyltransf_25 PF13649.6 KXH35273.1 - 0.0039 17.9 0.0 0.011 16.4 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain DUF2431 PF10354.9 KXH35273.1 - 0.0049 17.1 0.0 0.0087 16.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) PCMT PF01135.19 KXH35273.1 - 0.018 14.8 0.0 0.032 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 KXH35273.1 - 0.026 14.3 0.0 0.052 13.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.19 KXH35273.1 - 0.031 14.4 0.0 0.069 13.3 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase Mitofilin PF09731.9 KXH35273.1 - 8.7 5.1 32.7 6.6 5.5 6.9 2.2 2 0 0 2 2 2 0 Mitochondrial inner membrane protein Blt1 PF12754.7 KXH35274.1 - 9.2e-40 136.4 0.5 1.3e-39 136.0 0.5 1.2 1 0 0 1 1 1 1 Blt1 N-terminal domain Blt1_C PF17183.4 KXH35274.1 - 6.2e-14 51.3 0.9 1.1e-13 50.6 0.9 1.4 1 0 0 1 1 1 1 Get5 carboxyl domain ubiquitin PF00240.23 KXH35274.1 - 0.00018 21.2 0.0 0.00028 20.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Nse4-Nse3_bdg PF15412.6 KXH35274.1 - 0.14 12.3 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 Binding domain of Nse4/EID3 to Nse3-MAGE Cpn60_TCP1 PF00118.24 KXH35276.1 - 2.5e-87 293.6 12.0 4.7e-87 292.7 12.0 1.4 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF3810 PF12725.7 KXH35277.1 - 0.045 13.1 0.0 0.098 12.0 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3810) DUF5082 PF16888.5 KXH35279.1 - 0.0013 19.0 0.2 0.031 14.6 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF5082) Prominin PF05478.11 KXH35279.1 - 0.0061 14.6 5.8 0.026 12.5 6.1 1.6 1 1 1 2 2 2 2 Prominin Tweety PF04906.13 KXH35279.1 - 0.028 13.1 2.6 0.029 13.0 1.5 1.5 2 0 0 2 2 2 0 Tweety DUF1664 PF07889.12 KXH35279.1 - 0.032 14.3 1.1 0.32 11.0 0.1 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 KXH35279.1 - 0.28 11.2 16.9 0.78 9.8 13.7 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Lectin_N PF03954.14 KXH35279.1 - 0.55 10.0 3.8 3 7.6 3.2 2.3 1 1 0 1 1 1 0 Hepatic lectin, N-terminal domain Pox_Ag35 PF03286.14 KXH35280.1 - 0.28 11.0 4.8 0.42 10.4 4.8 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein PBP1_TM PF14812.6 KXH35281.1 - 2.6 8.5 10.3 10 6.6 3.0 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Transferase PF02458.15 KXH35282.1 - 2.6e-13 49.4 0.0 6.1e-07 28.5 0.0 2.1 2 0 0 2 2 2 2 Transferase family Isochorismatase PF00857.20 KXH35283.1 - 3.9e-15 56.5 0.0 5.9e-15 55.9 0.0 1.2 1 0 0 1 1 1 1 Isochorismatase family RRM_1 PF00076.22 KXH35306.1 - 4.1e-46 154.7 0.0 8.7e-16 57.5 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ATP-grasp_2 PF08442.10 KXH35306.1 - 0.00063 19.4 0.0 0.017 14.7 0.0 2.4 2 0 0 2 2 2 1 ATP-grasp domain Limkain-b1 PF11608.8 KXH35306.1 - 0.00065 19.7 0.2 6.9 6.8 0.0 3.7 4 1 0 4 4 4 1 Limkain b1 RRM_3 PF08777.11 KXH35306.1 - 0.0012 18.9 0.0 2.5 8.2 0.0 3.4 3 1 0 3 3 3 1 RNA binding motif GRP PF07172.11 KXH35306.1 - 0.011 16.4 12.5 0.011 16.4 12.5 4.1 3 1 1 4 4 4 0 Glycine rich protein family PknH_C PF14032.6 KXH35306.1 - 0.026 14.4 0.3 33 4.2 0.0 3.2 3 0 0 3 3 3 0 PknH-like extracellular domain RRM_occluded PF16842.5 KXH35306.1 - 0.045 13.6 0.0 1.8 8.5 0.0 2.6 3 0 0 3 3 3 0 Occluded RNA-recognition motif RRM_5 PF13893.6 KXH35306.1 - 0.084 12.5 0.0 14 5.3 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SRP14 PF02290.15 KXH35307.1 - 1.8e-15 57.0 0.0 3.1e-15 56.3 0.0 1.4 2 0 0 2 2 2 1 Signal recognition particle 14kD protein MIF4G PF02854.19 KXH35308.1 - 2.7e-20 72.9 0.0 1.2e-19 70.8 0.0 2.0 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.17 KXH35308.1 - 4.5e-12 46.0 0.0 1.3e-11 44.5 0.0 1.8 1 0 0 1 1 1 1 MA3 domain Pyr_redox_2 PF07992.14 KXH35309.1 - 9.4e-68 228.6 5.7 1.2e-67 228.3 5.7 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KXH35309.1 - 2.1e-40 137.4 0.0 4.7e-40 136.3 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KXH35309.1 - 6.7e-24 84.3 10.2 6.3e-22 77.9 0.6 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXH35309.1 - 5.5e-11 42.5 3.3 6.7e-06 26.2 0.5 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KXH35309.1 - 2.3e-10 40.4 7.6 3.1e-09 36.7 0.2 2.5 2 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KXH35309.1 - 4.5e-09 35.9 9.6 4.1e-07 29.4 3.6 3.1 3 0 0 3 3 3 2 FAD binding domain GIDA PF01134.22 KXH35309.1 - 6.9e-09 35.3 13.5 8e-08 31.8 4.4 2.9 2 2 1 3 3 3 2 Glucose inhibited division protein A HI0933_like PF03486.14 KXH35309.1 - 6.4e-07 28.4 12.6 0.00013 20.8 1.9 4.1 4 0 0 4 4 4 2 HI0933-like protein AlaDh_PNT_C PF01262.21 KXH35309.1 - 1.3e-06 27.9 3.7 0.017 14.5 0.2 2.6 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 KXH35309.1 - 1.5e-06 27.6 2.7 0.00015 21.0 0.1 2.4 2 0 0 2 2 2 2 Thi4 family Pyr_redox_3 PF13738.6 KXH35309.1 - 6.6e-06 25.6 3.5 0.0023 17.2 0.0 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXH35309.1 - 1.8e-05 24.5 15.1 0.015 14.9 1.6 4.0 4 0 0 4 4 4 2 FAD dependent oxidoreductase K_oxygenase PF13434.6 KXH35309.1 - 2.7e-05 23.5 0.1 0.23 10.5 0.0 2.8 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.12 KXH35309.1 - 5.7e-05 22.3 1.0 0.015 14.3 0.0 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein FAD_binding_3 PF01494.19 KXH35309.1 - 0.022 14.0 9.8 0.94 8.7 1.4 3.0 2 1 0 2 2 2 0 FAD binding domain 3HCDH_N PF02737.18 KXH35309.1 - 0.041 13.8 3.2 0.29 11.0 0.4 2.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RuBisCO_large PF00016.20 KXH35309.1 - 0.17 11.0 3.4 11 5.1 0.1 3.1 3 0 0 3 3 3 0 Ribulose bisphosphate carboxylase large chain, catalytic domain NAD_binding_7 PF13241.6 KXH35309.1 - 1.7 9.1 5.0 3.8 8.0 0.1 3.0 3 1 0 3 3 2 0 Putative NAD(P)-binding Trp_halogenase PF04820.14 KXH35309.1 - 2.2 7.0 7.3 0.73 8.6 1.1 2.1 2 0 0 2 2 2 0 Tryptophan halogenase CorA PF01544.18 KXH35392.1 - 0.00062 19.2 1.6 0.001 18.5 0.9 1.7 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein EMP70 PF02990.16 KXH35392.1 - 0.0087 14.8 0.0 0.013 14.2 0.0 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 PAP_PilO PF06864.12 KXH35392.1 - 0.059 12.2 0.1 0.11 11.3 0.1 1.4 1 0 0 1 1 1 0 Pilin accessory protein (PilO) COX16 PF14138.6 KXH35392.1 - 0.1 13.1 0.1 2.5 8.7 0.0 2.9 2 1 0 2 2 2 0 Cytochrome c oxidase assembly protein COX16 PI-PLC-X PF00388.19 KXH35393.1 - 4e-63 211.3 0.0 5.8e-63 210.8 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 KXH35393.1 - 2e-42 144.2 0.0 3.9e-42 143.2 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain FAM181 PF15238.6 KXH35393.1 - 0.0018 18.2 1.7 0.0036 17.2 1.7 1.5 1 0 0 1 1 1 1 FAM181 His_Phos_2 PF00328.22 KXH35395.1 - 2.7e-15 56.6 0.0 4.8e-11 42.6 0.0 2.8 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) Ferric_reduct PF01794.19 KXH35396.1 - 2e-16 60.2 15.1 2e-16 60.2 15.1 1.9 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KXH35396.1 - 5.2e-13 49.0 0.0 1.1e-12 48.0 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 KXH35396.1 - 6.4e-13 49.1 0.0 9.9e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain DUF373 PF04123.13 KXH35396.1 - 0.33 10.4 2.1 0.35 10.3 1.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF373) tRNA-synt_1d PF00750.19 KXH35397.1 - 9.7e-101 337.2 3.7 1.3e-100 336.8 3.7 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 KXH35397.1 - 1.5e-29 102.6 0.3 3.3e-29 101.5 0.3 1.6 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 KXH35397.1 - 0.0053 17.3 0.0 0.016 15.8 0.0 1.9 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain p450 PF00067.22 KXH35398.1 - 9.7e-54 182.8 0.0 1.9e-53 181.9 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 zf-C2H2 PF00096.26 KXH35586.1 - 0.002 18.5 1.3 0.002 18.5 1.3 2.9 4 1 0 4 4 4 1 Zinc finger, C2H2 type Clusterin PF01093.17 KXH35586.1 - 0.18 10.8 5.4 0.21 10.6 5.4 1.1 1 0 0 1 1 1 0 Clusterin DUF1640 PF07798.11 KXH35587.1 - 5.1e-47 160.2 3.5 5.1e-47 160.2 3.5 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1640) LEA_3 PF03242.13 KXH35587.1 - 0.28 11.9 0.2 0.28 11.9 0.2 3.5 3 0 0 3 3 3 0 Late embryogenesis abundant protein Pex14_N PF04695.13 KXH35587.1 - 1.3 9.7 14.9 0.052 14.2 7.3 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Roughex PF06020.11 KXH35587.1 - 5.2 6.1 9.1 8.2 5.4 9.1 1.3 1 0 0 1 1 1 0 Drosophila roughex protein PUF PF00806.19 KXH35588.1 - 4.4e-63 205.6 14.7 3.1e-08 32.9 0.1 8.3 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat SapB_2 PF03489.17 KXH35588.1 - 0.092 12.9 1.1 7.5 6.8 0.1 3.0 2 0 0 2 2 2 0 Saposin-like type B, region 2 TFIID_30kDa PF03540.13 KXH35588.1 - 0.13 12.2 0.0 0.37 10.8 0.0 1.7 1 0 0 1 1 1 0 Transcription initiation factor TFIID 23-30kDa subunit MFS_1 PF07690.16 KXH35595.1 - 3.6e-12 45.9 19.0 5.9e-12 45.2 19.0 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 KXH35595.1 - 0.00038 20.2 1.7 0.00038 20.2 1.7 1.8 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 Sugar_tr PF00083.24 KXH35595.1 - 0.00041 19.3 5.2 0.00078 18.4 5.2 1.4 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.6 KXH35595.1 - 0.0081 14.8 7.1 0.5 8.9 2.3 2.8 2 1 1 3 3 3 2 MFS/sugar transport protein FMO-like PF00743.19 KXH35596.1 - 2.2e-25 89.1 0.0 1.1e-10 40.6 0.1 3.1 2 1 1 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KXH35596.1 - 3.6e-14 52.7 0.5 2.4e-10 40.2 0.3 3.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXH35596.1 - 4e-12 46.0 0.0 1.4e-11 44.2 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXH35596.1 - 4.5e-09 35.9 0.1 1e-06 28.1 0.1 2.3 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KXH35596.1 - 3.8e-07 30.2 0.0 0.00015 21.7 0.0 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KXH35596.1 - 3.9e-06 27.0 0.0 1e-05 25.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXH35596.1 - 0.00021 21.0 0.3 0.65 9.5 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.17 KXH35596.1 - 0.011 14.9 0.3 0.024 13.9 0.0 1.6 2 0 0 2 2 2 0 Thi4 family Pyr_redox PF00070.27 KXH35596.1 - 0.057 14.0 1.0 2.1 8.9 0.0 3.1 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Glu_dehyd_C PF16912.5 KXH35596.1 - 0.15 11.6 0.0 0.32 10.4 0.0 1.5 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus TssN PF17555.2 KXH35598.1 - 0.16 11.4 6.7 0.21 10.9 6.7 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssN Sugar_tr PF00083.24 KXH35599.1 - 7.1e-88 295.4 23.8 8.4e-88 295.2 23.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH35599.1 - 1.8e-17 63.3 28.5 2.4e-14 53.1 22.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KXH35599.1 - 0.01 14.4 22.3 0.018 13.6 9.2 2.7 2 1 1 3 3 3 0 MFS/sugar transport protein Sterol_MT_C PF08498.10 KXH35600.1 - 9.3e-28 96.3 0.8 1.6e-27 95.6 0.8 1.4 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal DUF202 PF02656.15 KXH35630.1 - 0.00012 22.5 2.9 0.00012 22.5 2.9 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF202) zf-C2H2 PF00096.26 KXH35631.1 - 0.0026 18.1 21.1 0.0033 17.8 0.5 4.2 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXH35631.1 - 0.0059 17.4 0.7 0.0059 17.4 0.7 4.2 4 0 0 4 4 4 1 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KXH35631.1 - 0.0067 16.7 2.4 0.02 15.2 2.4 1.7 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) FOXP-CC PF16159.5 KXH35631.1 - 1.9 9.2 8.0 3.9 8.2 0.9 3.1 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-C2H2_6 PF13912.6 KXH35631.1 - 3.9 7.6 6.6 0.23 11.5 0.8 2.0 2 0 0 2 2 2 0 C2H2-type zinc finger MFS_5 PF05631.14 KXH35742.1 - 2.5e-70 237.2 9.7 3.7e-70 236.6 9.7 1.2 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 KXH35742.1 - 2.9e-17 62.6 27.5 2.9e-17 62.6 27.5 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH35742.1 - 0.00024 20.1 23.1 0.0087 15.0 9.7 2.6 2 1 1 3 3 3 2 Sugar (and other) transporter Colicin_V PF02674.16 KXH35742.1 - 0.17 11.9 11.2 5.3 7.0 6.0 2.8 2 0 0 2 2 2 0 Colicin V production protein Vpu PF00558.19 KXH35742.1 - 0.3 10.9 1.0 0.7 9.7 0.1 2.0 2 0 0 2 2 2 0 Vpu protein Hexokinase_1 PF00349.21 KXH35743.1 - 4.8e-76 255.1 0.0 7.8e-76 254.4 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.16 KXH35743.1 - 1.8e-74 250.2 0.0 2.5e-74 249.7 0.0 1.2 1 0 0 1 1 1 1 Hexokinase DUF4574 PF15141.6 KXH35743.1 - 0.018 15.0 0.1 0.036 14.0 0.1 1.4 1 0 0 1 1 1 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 Acetyltransf_1 PF00583.25 KXH35744.1 - 7.7e-06 26.1 0.0 1e-05 25.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXH35744.1 - 0.0075 16.7 0.0 0.011 16.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Sgf11 PF08209.11 KXH35745.1 - 0.12 12.0 3.1 0.25 11.0 3.1 1.5 1 0 0 1 1 1 0 Sgf11 (transcriptional regulation protein) zf_UBZ PF18439.1 KXH35745.1 - 0.3 10.7 1.9 2.9 7.6 0.3 2.3 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Pro_isomerase PF00160.21 KXH35746.1 - 1.4e-51 174.9 0.0 1.6e-51 174.7 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Peptidase_A22B PF04258.13 KXH35747.1 - 4.6e-59 200.3 9.5 2.9e-38 132.0 3.4 2.3 2 1 0 2 2 2 2 Signal peptide peptidase Methyltransf_2 PF00891.18 KXH35748.1 - 4.6e-21 75.1 0.0 1.5e-20 73.4 0.0 1.7 1 1 0 1 1 1 1 O-methyltransferase domain DUF3662 PF12401.8 KXH35748.1 - 0.085 13.2 0.0 0.18 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2662) AA_permease PF00324.21 KXH35749.1 - 1.1e-136 456.3 34.3 1.2e-136 456.1 34.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KXH35749.1 - 7.1e-37 127.2 37.8 9.3e-37 126.9 37.8 1.1 1 0 0 1 1 1 1 Amino acid permease RbsD_FucU PF05025.13 KXH35751.1 - 1.5e-35 122.5 0.0 1.7e-35 122.4 0.0 1.0 1 0 0 1 1 1 1 RbsD / FucU transport protein family ABC2_membrane PF01061.24 KXH35752.1 - 5.6e-85 284.0 53.2 6.2e-47 159.7 24.5 2.4 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 KXH35752.1 - 9.7e-40 136.3 0.0 9e-19 68.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KXH35752.1 - 3.9e-28 97.2 9.3 3.7e-26 90.9 0.0 3.7 3 0 0 3 3 3 2 CDR ABC transporter ABC2_membrane_3 PF12698.7 KXH35752.1 - 3.3e-10 39.6 42.4 1.1e-07 31.4 15.6 2.4 3 0 0 3 3 2 2 ABC-2 family transporter protein ABC_trans_N PF14510.6 KXH35752.1 - 6.2e-08 33.1 0.0 6.2e-08 33.1 0.0 2.2 3 0 0 3 3 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 KXH35752.1 - 1.5e-06 28.7 0.1 0.0072 16.7 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KXH35752.1 - 4e-05 23.6 0.1 0.0059 16.5 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 KXH35752.1 - 0.00011 21.8 0.1 0.0071 15.9 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KXH35752.1 - 0.00024 21.3 0.1 1.2 9.3 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.6 KXH35752.1 - 0.00035 20.8 0.1 0.71 10.1 0.1 3.0 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KXH35752.1 - 0.00041 20.0 0.3 0.087 12.6 0.1 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_28 PF13521.6 KXH35752.1 - 0.00063 20.0 0.4 0.81 9.9 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KXH35752.1 - 0.0025 18.3 0.0 3.2 8.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain cobW PF02492.19 KXH35752.1 - 0.0032 17.1 1.1 1.4 8.5 0.2 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 KXH35752.1 - 0.044 13.7 0.4 4.2 7.3 0.2 2.4 2 0 0 2 2 2 0 NACHT domain Zeta_toxin PF06414.12 KXH35752.1 - 0.063 12.5 0.1 2.4 7.4 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin MMR_HSR1 PF01926.23 KXH35752.1 - 0.065 13.3 0.1 15 5.7 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_30 PF13604.6 KXH35752.1 - 0.074 12.8 0.7 6.3 6.5 0.3 2.5 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 KXH35752.1 - 0.094 11.8 0.0 2.9 6.9 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein DnaB_C PF03796.15 KXH35752.1 - 0.14 11.5 0.0 0.96 8.7 0.0 2.0 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain PduV-EutP PF10662.9 KXH35752.1 - 0.22 11.3 0.4 8.1 6.2 0.1 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Fungal_trans PF04082.18 KXH35753.1 - 2.6e-11 43.1 0.0 4.6e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain tRNA-synt_2_TM PF16995.5 KXH35753.1 - 0.04 13.6 0.2 2.3 7.9 0.0 2.2 2 0 0 2 2 2 0 Transmembrane region of lysyl-tRNA synthetase PhoU PF01895.19 KXH35753.1 - 0.12 12.8 0.1 0.33 11.5 0.1 1.7 1 0 0 1 1 1 0 PhoU domain Nnf1 PF03980.14 KXH35753.1 - 0.13 12.6 0.1 0.51 10.7 0.0 2.0 2 0 0 2 2 2 0 Nnf1 Solute_trans_a PF03619.16 KXH35973.1 - 4.2e-86 288.8 24.6 5.1e-86 288.5 24.6 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Mid2 PF04478.12 KXH35974.1 - 0.15 11.9 0.0 0.34 10.8 0.0 1.5 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor RSN1_7TM PF02714.15 KXH35976.1 - 5.8e-85 284.9 28.3 5.8e-85 284.9 28.3 1.7 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KXH35976.1 - 1.8e-44 151.3 1.0 1.8e-44 151.3 1.0 3.0 5 0 0 5 5 5 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KXH35976.1 - 1.7e-37 129.4 0.2 2.4e-37 128.9 0.2 1.2 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 KXH35976.1 - 6.7e-31 106.3 0.1 2.1e-30 104.7 0.1 1.8 2 0 0 2 2 2 1 Extracellular tail, of 10TM putative phosphate transporter kleA_kleC PF17383.2 KXH35976.1 - 0.13 12.6 2.3 0.36 11.2 0.6 2.3 2 0 0 2 2 2 0 Uncharacterized KorC regulated protein A Zn_clus PF00172.18 KXH35977.1 - 4.4e-08 33.1 7.6 9.7e-08 32.0 7.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3379 PF11859.8 KXH35978.1 - 0.22 10.8 0.5 0.5 9.7 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3379) Glyco_transf_34 PF05637.12 KXH35979.1 - 6.2e-19 68.7 0.0 1e-18 67.9 0.0 1.3 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family THOC2_N PF16134.5 KXH35981.1 - 3.7e-246 818.7 0.0 3.7e-246 818.7 0.0 1.9 2 0 0 2 2 2 1 THO complex subunit 2 N-terminus Tho2 PF11262.8 KXH35981.1 - 7.2e-96 320.9 0.0 1.7e-95 319.7 0.0 1.7 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.8 KXH35981.1 - 4.3e-27 94.0 0.1 8.7e-27 93.0 0.1 1.6 1 0 0 1 1 1 1 Transcription- and export-related complex subunit Abhydrolase_1 PF00561.20 KXH35982.1 - 3.9e-47 161.0 0.0 8e-47 160.0 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXH35982.1 - 0.015 15.9 4.4 0.031 14.9 4.4 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family ARPC4 PF05856.12 KXH36004.1 - 3.6e-79 264.2 4.1 4e-79 264.1 4.1 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) UCH PF00443.29 KXH36005.1 - 1.3e-49 169.1 0.0 1.8e-49 168.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KXH36005.1 - 1.3e-12 48.0 6.8 7.1e-11 42.3 6.8 2.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 KXH36005.1 - 3.8e-12 45.8 0.2 8.5e-11 41.5 0.0 2.4 2 0 0 2 2 2 1 Ubiquitin family EPO_TPO PF00758.18 KXH36005.1 - 0.013 15.5 0.1 4.2 7.4 0.0 2.3 2 0 0 2 2 2 0 Erythropoietin/thrombopoietin Ubiquitin_2 PF14560.6 KXH36005.1 - 0.017 15.6 0.1 0.19 12.2 0.0 2.4 2 0 0 2 2 2 0 Ubiquitin-like domain TBK1_ULD PF18396.1 KXH36005.1 - 0.18 11.8 0.0 0.38 10.7 0.0 1.5 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain SR-25 PF10500.9 KXH36007.1 - 0.26 10.9 7.1 0.35 10.4 7.1 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein His_Phos_1 PF00300.22 KXH36008.1 - 7.6e-37 126.9 1.1 1e-34 120.0 1.1 2.4 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Zip PF02535.22 KXH36010.1 - 9.7e-53 179.5 1.4 3.4e-52 177.7 1.4 1.7 1 1 0 1 1 1 1 ZIP Zinc transporter Cation_efflux PF01545.21 KXH36011.1 - 1.7e-25 89.9 14.6 2.1e-25 89.6 14.6 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KXH36011.1 - 3.2e-09 36.8 0.2 6.9e-09 35.7 0.2 1.5 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter HTH_31 PF13560.6 KXH36012.1 - 0.15 12.5 0.0 0.72 10.3 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain Hexapep PF00132.24 KXH36013.1 - 4.3e-07 29.4 11.7 0.00011 21.8 2.5 3.8 4 0 0 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KXH36013.1 - 1.3e-05 24.8 12.5 0.011 15.5 1.7 3.1 2 1 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Complex1_51K PF01512.17 KXH36014.1 - 2.3e-47 160.7 0.0 3.6e-47 160.1 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 KXH36014.1 - 4.6e-29 100.3 0.9 8.4e-29 99.5 0.1 1.8 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 KXH36014.1 - 8.4e-09 35.2 0.0 2.2e-08 33.9 0.0 1.8 1 0 0 1 1 1 1 SLBB domain PEX11 PF05648.14 KXH36015.1 - 7.4e-15 55.0 0.0 4.1e-13 49.3 0.0 3.0 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) CUE PF02845.16 KXH36017.1 - 3.2e-06 26.7 0.6 0.002 17.8 0.1 3.2 3 0 0 3 3 3 2 CUE domain Smr PF01713.21 KXH36017.1 - 0.0011 19.3 0.1 0.003 17.9 0.1 1.8 2 0 0 2 2 2 1 Smr domain DUF1771 PF08590.10 KXH36017.1 - 0.36 11.3 6.8 0.77 10.2 6.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1771) Amidase PF01425.21 KXH36018.1 - 6.8e-74 249.5 0.0 1.7e-72 244.8 0.0 2.0 1 1 0 1 1 1 1 Amidase RRM_1 PF00076.22 KXH36076.1 - 2.6e-29 100.8 0.0 2.5e-13 49.7 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HLH PF00010.26 KXH36076.1 - 3.6e-12 46.0 1.2 1.2e-11 44.3 1.2 2.0 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain NRBF2 PF08961.10 KXH36076.1 - 0.0017 18.0 4.9 0.0037 16.9 4.9 1.5 1 0 0 1 1 1 1 Nuclear receptor-binding factor 2, autophagy regulator Rootletin PF15035.6 KXH36076.1 - 0.0026 17.8 4.9 0.0026 17.8 4.9 1.8 2 0 0 2 2 2 1 Ciliary rootlet component, centrosome cohesion KLRAQ PF10205.9 KXH36076.1 - 0.0065 16.7 0.3 0.019 15.2 0.3 1.7 1 0 0 1 1 1 1 Predicted coiled-coil domain-containing protein RRM_3 PF08777.11 KXH36076.1 - 0.039 14.0 0.1 0.6 10.2 0.0 2.5 2 0 0 2 2 2 0 RNA binding motif RRM_5 PF13893.6 KXH36076.1 - 0.11 12.1 0.0 0.47 10.0 0.0 2.0 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Phage_GPO PF05929.11 KXH36076.1 - 0.15 11.7 2.7 0.36 10.4 2.7 1.6 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DivIC PF04977.15 KXH36076.1 - 0.19 11.5 0.9 0.85 9.4 0.9 2.1 1 0 0 1 1 1 0 Septum formation initiator GIT_CC PF16559.5 KXH36076.1 - 3.1 7.7 8.3 1.3 8.9 1.2 2.4 1 1 1 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor zf-H2C2_2 PF13465.6 KXH36079.1 - 1.6e-09 37.7 18.6 2e-05 24.8 3.5 4.1 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.26 KXH36079.1 - 2.9e-06 27.4 20.8 0.00045 20.5 4.5 2.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXH36079.1 - 0.0014 19.3 16.1 0.051 14.4 3.1 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KXH36079.1 - 0.053 13.8 0.4 0.053 13.8 0.4 2.6 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 KXH36079.1 - 0.12 13.1 0.1 0.12 13.1 0.1 2.8 3 1 1 4 4 4 0 FOXP coiled-coil domain zf-C2H2_6 PF13912.6 KXH36079.1 - 0.26 11.3 5.8 2.3 8.3 0.3 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger DUF2225 PF09986.9 KXH36079.1 - 0.3 10.8 0.8 0.61 9.8 0.8 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-H2C2_5 PF13909.6 KXH36079.1 - 3 7.7 12.9 3.1 7.6 0.1 3.6 3 0 0 3 3 3 0 C2H2-type zinc-finger domain Rad51 PF08423.11 KXH36080.1 - 2.1e-07 30.5 0.0 0.0015 17.9 0.0 2.1 1 1 1 2 2 2 2 Rad51 ATPase PF06745.13 KXH36080.1 - 2.1e-05 24.0 0.1 6.2e-05 22.5 0.0 1.7 1 1 1 2 2 2 1 KaiC RecA PF00154.21 KXH36080.1 - 2.1e-05 24.1 0.5 0.00072 19.1 0.1 2.1 1 1 1 2 2 2 1 recA bacterial DNA recombination protein AAA_24 PF13479.6 KXH36080.1 - 0.0075 16.0 0.0 0.91 9.2 0.0 2.3 1 1 1 2 2 2 2 AAA domain DnaB_C PF03796.15 KXH36080.1 - 0.019 14.3 0.1 0.89 8.8 0.0 2.1 1 1 1 2 2 2 0 DnaB-like helicase C terminal domain AAA_25 PF13481.6 KXH36080.1 - 0.028 14.0 1.6 0.26 10.8 0.5 2.5 1 1 1 2 2 2 0 AAA domain AAA_11 PF13086.6 KXH36080.1 - 0.056 13.2 0.0 0.079 12.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain SLATT_fungal PF18142.1 KXH36082.1 - 6.2e-28 97.2 0.0 1.3e-27 96.2 0.0 1.6 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain SLATT_1 PF18181.1 KXH36082.1 - 0.087 12.8 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 1 TIM21 PF08294.11 KXH36083.1 - 1e-42 145.5 0.1 1.3e-42 145.2 0.1 1.1 1 0 0 1 1 1 1 TIM21 Coa1 PF08695.10 KXH36083.1 - 7.2e-06 25.7 0.0 1.3e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 Carla_C4 PF01623.17 KXH36083.1 - 0.12 12.3 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Carlavirus putative nucleic acid binding protein ArfGap PF01412.18 KXH36084.1 - 6.9e-35 119.6 0.1 1.3e-34 118.7 0.1 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf NMO PF03060.15 KXH36085.1 - 7.9e-56 189.8 1.3 1e-55 189.5 1.3 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KXH36085.1 - 8.4e-12 44.7 1.1 1.4e-11 44.1 1.1 1.3 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KXH36085.1 - 3.7e-06 26.2 2.8 5.8e-06 25.6 2.8 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 KXH36085.1 - 0.0014 17.8 0.8 0.0037 16.5 0.8 1.6 1 0 0 1 1 1 1 Conserved region in glutamate synthase DHO_dh PF01180.21 KXH36085.1 - 0.015 14.5 0.1 0.023 13.9 0.1 1.2 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase NanE PF04131.14 KXH36085.1 - 0.068 12.4 0.1 0.16 11.1 0.1 1.6 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase Pterin_bind PF00809.22 KXH36086.1 - 1.3e-74 251.0 0.0 1.7e-74 250.6 0.0 1.2 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.20 KXH36086.1 - 2.7e-36 124.5 0.0 7.1e-36 123.1 0.0 1.7 2 0 0 2 2 2 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) GFO_IDH_MocA PF01408.22 KXH36087.1 - 8.3e-16 58.9 0.0 1.5e-15 58.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 KXH36087.1 - 0.091 13.4 0.9 0.18 12.5 0.9 1.5 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain SET PF00856.28 KXH36089.1 - 8.5e-12 45.8 0.0 4.2e-11 43.5 0.0 2.1 1 1 0 1 1 1 1 SET domain CAP59_mtransfer PF11735.8 KXH36090.1 - 7e-64 215.8 0.0 8.9e-64 215.5 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 SOG2 PF10428.9 KXH36091.1 - 1.7 7.7 21.4 2.1 7.5 21.4 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein MFS_1 PF07690.16 KXH36153.1 - 3.3e-44 151.3 52.4 5.8e-44 150.4 52.4 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH36153.1 - 2.5e-14 53.0 36.9 1.4e-11 44.0 15.0 3.0 3 0 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.13 KXH36153.1 - 4.9e-12 45.1 29.1 1.3e-11 43.7 29.1 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) LtrA PF06772.11 KXH36154.1 - 3.3e-23 82.5 13.9 3.3e-23 82.5 13.9 2.1 2 0 0 2 2 2 2 Bacterial low temperature requirement A protein (LtrA) Fructosamin_kin PF03881.14 KXH36155.1 - 2.7e-21 76.0 0.1 2.4e-13 50.0 0.1 2.1 1 1 0 2 2 2 2 Fructosamine kinase Fungal_trans PF04082.18 KXH36156.1 - 2.4e-10 39.9 0.0 4.4e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DAO PF01266.24 KXH36157.1 - 6.6e-38 131.2 0.0 8.4e-38 130.8 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXH36157.1 - 3.6e-07 30.3 0.0 1.9e-06 28.0 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXH36157.1 - 5.3e-05 22.6 0.0 0.0029 16.9 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 KXH36157.1 - 0.00032 20.8 0.0 0.023 14.8 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.24 KXH36157.1 - 0.0025 17.0 0.2 0.055 12.5 0.2 2.2 1 1 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 KXH36157.1 - 0.0046 16.2 0.0 0.0066 15.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 KXH36157.1 - 0.0063 17.1 0.1 0.023 15.2 0.0 2.0 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KXH36157.1 - 0.017 14.2 0.1 3.5 6.6 0.1 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A TrkA_N PF02254.18 KXH36157.1 - 0.021 15.0 0.0 0.066 13.5 0.0 1.8 2 0 0 2 2 2 0 TrkA-N domain NAD_binding_9 PF13454.6 KXH36157.1 - 0.028 14.4 0.0 0.95 9.4 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding GMC_oxred_N PF00732.19 KXH36157.1 - 0.044 13.1 0.1 0.35 10.2 0.0 2.0 2 0 0 2 2 2 0 GMC oxidoreductase ApbA PF02558.16 KXH36157.1 - 0.068 12.8 0.1 0.16 11.6 0.0 1.6 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Glu_dehyd_C PF16912.5 KXH36157.1 - 0.1 12.1 0.2 0.2 11.1 0.0 1.6 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus Sacchrp_dh_NADP PF03435.18 KXH36157.1 - 0.12 12.7 0.0 0.31 11.3 0.0 1.7 2 0 0 2 2 1 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_7 PF13241.6 KXH36157.1 - 0.15 12.5 0.0 0.32 11.5 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox_3 PF13738.6 KXH36157.1 - 0.21 10.8 0.0 0.47 9.7 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.16 KXH36158.1 - 1.4e-25 89.9 27.6 8.6e-25 87.4 25.6 2.2 1 1 2 3 3 3 2 Major Facilitator Superfamily GMC_oxred_N PF00732.19 KXH36159.1 - 8.4e-54 182.9 0.0 1.1e-53 182.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXH36159.1 - 1.6e-26 93.6 0.0 5.7e-26 91.8 0.0 1.9 2 0 0 2 2 2 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KXH36159.1 - 2.3e-07 30.2 0.0 7.2e-06 25.3 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.24 KXH36159.1 - 3.2e-05 23.7 2.8 0.00052 19.7 2.8 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KXH36159.1 - 0.00014 21.1 0.3 0.13 11.3 0.2 2.2 2 0 0 2 2 2 2 FAD binding domain GIDA PF01134.22 KXH36159.1 - 0.00076 18.7 0.1 0.56 9.2 0.0 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 KXH36159.1 - 0.0016 17.7 0.1 0.2 10.8 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXH36159.1 - 0.0079 16.4 0.1 0.022 15.0 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KXH36159.1 - 0.041 12.6 0.3 0.58 8.8 0.1 2.0 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_9 PF13454.6 KXH36159.1 - 0.076 13.0 0.3 4.6 7.2 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox PF00070.27 KXH36159.1 - 0.1 13.2 0.2 0.7 10.5 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Cupin_1 PF00190.22 KXH36160.1 - 8.2e-16 58.0 0.9 8.2e-16 58.0 0.9 1.5 2 0 0 2 2 2 1 Cupin Cupin_2 PF07883.11 KXH36160.1 - 0.033 13.9 0.0 0.068 12.9 0.0 1.5 1 0 0 1 1 1 0 Cupin domain DUF685 PF05085.12 KXH36161.1 - 0.0043 16.4 0.5 0.0071 15.7 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF685) DAO PF01266.24 KXH36162.1 - 1e-36 127.2 0.1 1.2e-36 127.0 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXH36162.1 - 3.3e-07 29.9 0.0 0.012 14.8 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXH36162.1 - 2.4e-06 27.7 0.0 7.1e-06 26.2 0.0 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KXH36162.1 - 4.4e-06 26.0 0.1 0.0064 15.6 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.6 KXH36162.1 - 7.8e-06 25.4 0.0 0.00011 21.5 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KXH36162.1 - 1.3e-05 24.8 0.0 0.0024 17.2 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 KXH36162.1 - 2.4e-05 24.8 0.0 0.083 13.5 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXH36162.1 - 2.5e-05 23.2 0.1 0.024 13.4 0.0 2.3 2 0 0 2 2 2 2 HI0933-like protein GIDA PF01134.22 KXH36162.1 - 0.00033 19.9 0.3 0.41 9.7 0.0 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.17 KXH36162.1 - 0.0011 18.2 0.0 0.002 17.4 0.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 KXH36162.1 - 0.043 13.1 0.0 0.067 12.4 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Shikimate_DH PF01488.20 KXH36162.1 - 0.085 12.9 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ThiF PF00899.21 KXH36162.1 - 0.1 12.0 0.0 0.21 10.9 0.0 1.5 1 0 0 1 1 1 0 ThiF family NAD_binding_9 PF13454.6 KXH36162.1 - 0.1 12.6 0.1 13 5.8 0.1 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding MFS_1 PF07690.16 KXH36163.1 - 4.1e-22 78.6 28.9 4.1e-22 78.6 28.9 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 KXH36163.1 - 0.0018 17.7 0.3 0.0018 17.7 0.3 2.2 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB Hydantoinase_B PF02538.14 KXH36164.1 - 4.7e-201 668.7 0.0 6.5e-201 668.2 0.0 1.2 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 KXH36164.1 - 2.5e-97 325.6 0.2 7.6e-97 324.1 0.1 1.8 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 KXH36164.1 - 5.8e-59 198.8 0.0 2.4e-57 193.5 0.0 2.5 3 0 0 3 3 3 1 Hydantoinase/oxoprolinase N-terminal region HET PF06985.11 KXH36165.1 - 1.1e-24 87.4 0.7 2.4e-24 86.3 0.7 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) RTA1 PF04479.13 KXH36166.1 - 1.5e-66 224.0 13.2 1.6e-66 223.8 10.5 1.9 2 0 0 2 2 2 1 RTA1 like protein YchF-GTPase_C PF06071.13 KXH36168.1 - 2e-36 124.0 0.0 4.6e-36 122.9 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 KXH36168.1 - 4.9e-21 74.9 0.0 1.2e-20 73.7 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KXH36168.1 - 9.9e-08 31.7 0.0 1.9e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Arginosuc_synth PF00764.19 KXH36169.1 - 1e-150 502.4 0.0 1.1e-150 502.2 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 KXH36169.1 - 0.006 16.1 0.0 0.0094 15.5 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 KXH36169.1 - 0.067 12.0 0.0 0.099 11.4 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase Copper-fist PF00649.18 KXH36183.1 - 2.4e-22 78.1 2.9 2.4e-22 78.1 2.9 3.1 1 1 2 3 3 3 1 Copper fist DNA binding domain Leu_leader PF08054.11 KXH36183.1 - 0.18 11.5 0.2 6.8 6.4 0.1 2.3 2 0 0 2 2 2 0 Leucine operon leader peptide LEA_6 PF10714.9 KXH36183.1 - 0.28 11.2 1.0 16 5.6 0.1 2.6 2 0 0 2 2 2 0 Late embryogenesis abundant protein 18 GPR15L PF15854.5 KXH36183.1 - 5.8 7.2 7.8 2.4 8.4 5.0 1.8 2 0 0 2 2 2 0 G-protein coupled receptor ligand 15 zinc-ribbons_6 PF07191.12 KXH36183.1 - 8.8 6.4 12.1 4.2 7.4 9.3 1.9 2 0 0 2 2 2 0 zinc-ribbons ApbA PF02558.16 KXH36184.1 - 8.3e-35 119.7 0.0 1.1e-34 119.3 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 KXH36184.1 - 3.7e-27 95.0 0.0 5.6e-27 94.4 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal GFO_IDH_MocA PF01408.22 KXH36184.1 - 0.028 15.2 0.0 0.06 14.2 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold PHY PF00360.20 KXH36185.1 - 1.4e-27 96.2 0.0 3.1e-27 95.1 0.0 1.5 1 0 0 1 1 1 1 Phytochrome region HATPase_c PF02518.26 KXH36185.1 - 3.7e-20 72.5 1.4 3.9e-20 72.4 0.1 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KXH36185.1 - 6.2e-18 65.0 0.0 3.3e-17 62.7 0.0 2.1 1 1 0 1 1 1 1 Response regulator receiver domain GAF PF01590.26 KXH36185.1 - 7.6e-13 49.2 0.0 2.2e-12 47.8 0.0 1.8 1 0 0 1 1 1 1 GAF domain HisKA PF00512.25 KXH36185.1 - 1.4e-12 47.4 0.7 6e-12 45.4 0.7 2.1 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_2 PF08446.11 KXH36185.1 - 9.6e-08 32.7 0.0 3.8e-07 30.7 0.0 2.1 2 0 0 2 2 2 1 PAS fold HATPase_c_3 PF13589.6 KXH36185.1 - 0.025 14.4 0.0 0.056 13.3 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 KXH36185.1 - 0.091 12.7 0.0 0.29 11.1 0.0 1.9 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain SLATT_5 PF18160.1 KXH36186.1 - 3.4 6.9 6.6 6.5 6.0 0.1 2.8 2 1 1 3 3 3 0 SMODS and SLOG-associating 2TM effector domain family 5 ABC_tran PF00005.27 KXH36187.1 - 2.9e-47 160.6 0.5 2.3e-25 89.7 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 KXH36187.1 - 5.4e-26 91.5 36.9 8.1e-15 54.8 18.6 2.6 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.6 KXH36187.1 - 7.3e-18 65.4 6.3 2.9e-05 24.1 0.0 4.6 4 1 1 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KXH36187.1 - 1.2e-08 34.5 1.8 0.001 18.8 0.2 3.6 4 0 0 4 4 3 2 P-loop containing region of AAA domain SMC_N PF02463.19 KXH36187.1 - 2.7e-07 30.3 1.8 0.16 11.4 0.0 3.6 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KXH36187.1 - 6.6e-07 30.0 0.7 0.043 14.3 0.3 2.3 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KXH36187.1 - 2.1e-05 24.5 0.3 0.12 12.3 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_15 PF13175.6 KXH36187.1 - 0.00064 19.5 0.0 1.5 8.5 0.1 3.2 3 0 0 3 3 3 1 AAA ATPase domain ABC2_membrane PF01061.24 KXH36187.1 - 0.00076 19.0 15.9 0.00076 19.0 15.9 3.9 3 1 0 3 3 3 1 ABC-2 type transporter DUF4162 PF13732.6 KXH36187.1 - 0.0034 18.1 0.0 3.9 8.3 0.0 2.8 3 0 0 3 3 2 1 Domain of unknown function (DUF4162) AAA_16 PF13191.6 KXH36187.1 - 0.0043 17.4 0.2 2.2 8.6 0.1 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_27 PF13514.6 KXH36187.1 - 0.0051 16.4 0.1 0.78 9.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KXH36187.1 - 0.0094 16.2 0.0 3.5 7.9 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KXH36187.1 - 0.014 15.1 0.4 4.4 7.0 0.0 2.8 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KXH36187.1 - 0.02 14.2 0.3 5.5 6.2 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin Rad17 PF03215.15 KXH36187.1 - 0.025 14.5 0.1 10 6.0 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain SRP54 PF00448.22 KXH36187.1 - 0.039 13.6 0.6 10 5.7 0.3 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain RNA_helicase PF00910.22 KXH36187.1 - 0.054 13.9 0.0 3 8.3 0.0 2.5 2 0 0 2 2 2 0 RNA helicase DUF87 PF01935.17 KXH36187.1 - 0.062 13.4 1.6 2.5 8.1 0.0 2.8 3 0 0 3 3 3 0 Helicase HerA, central domain AAA_24 PF13479.6 KXH36187.1 - 0.075 12.7 0.1 12 5.5 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_PrkA PF08298.11 KXH36187.1 - 0.099 11.5 0.0 4.8 6.0 0.0 2.3 2 0 0 2 2 2 0 PrkA AAA domain MukB PF04310.12 KXH36187.1 - 0.15 11.8 0.3 9.6 5.9 0.0 2.5 2 0 0 2 2 2 0 MukB N-terminal AAA PF00004.29 KXH36187.1 - 0.17 12.3 0.2 25 5.3 0.0 3.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 KXH36187.1 - 0.78 10.0 3.7 60 3.8 2.5 3.0 3 0 0 3 3 3 0 AAA domain AIG1 PF04548.16 KXH36187.1 - 0.94 8.8 2.3 2.5 7.4 0.7 2.2 2 0 0 2 2 2 0 AIG1 family SET PF00856.28 KXH36188.1 - 0.069 13.5 0.0 3.2 8.1 0.0 2.5 2 1 0 3 3 3 0 SET domain Nup96 PF12110.8 KXH36189.1 - 5.2e-97 324.5 2.7 7.2e-97 324.0 2.7 1.2 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.14 KXH36189.1 - 6.7e-52 175.6 0.0 1.1e-51 174.8 0.0 1.4 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.6 KXH36189.1 - 3.3e-12 47.1 345.5 0.0002 22.1 31.3 11.9 3 2 6 9 9 9 6 Nucleoporin FG repeat region ENTH PF01417.20 KXH36190.1 - 1.4e-50 170.5 0.1 2.4e-50 169.8 0.1 1.4 1 0 0 1 1 1 1 ENTH domain DUF1720 PF08226.11 KXH36190.1 - 5.9e-05 23.4 18.5 5.9e-05 23.4 18.5 6.2 2 1 3 5 5 5 1 Domain of unknown function (DUF1720) UIM PF02809.20 KXH36190.1 - 0.0012 18.6 4.1 0.0023 17.7 0.2 2.7 2 1 0 2 2 2 1 Ubiquitin interaction motif ANTH PF07651.16 KXH36190.1 - 0.0041 16.1 0.0 0.0062 15.6 0.0 1.2 1 0 0 1 1 1 1 ANTH domain VHS PF00790.19 KXH36190.1 - 0.031 14.1 0.0 0.057 13.3 0.0 1.4 1 0 0 1 1 1 0 VHS domain DUF4264 PF14084.6 KXH36190.1 - 0.1 12.2 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4264) DEC-1_C PF04626.13 KXH36190.1 - 0.15 12.4 8.1 0.07 13.5 3.7 2.3 2 0 0 2 2 2 0 Dec-1 protein, C terminal region MOZ_SAS PF01853.18 KXH36191.1 - 1.1e-74 250.0 0.0 1.7e-74 249.4 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 KXH36191.1 - 7.3e-21 73.5 3.1 1.5e-20 72.6 3.1 1.5 1 0 0 1 1 1 1 MYST family zinc finger domain PHD_4 PF16866.5 KXH36191.1 - 5.3e-08 32.8 8.6 5.3e-08 32.8 8.6 1.9 2 0 0 2 2 2 1 PHD-finger PHD PF00628.29 KXH36191.1 - 0.0034 17.2 9.0 0.0034 17.2 9.0 2.2 2 0 0 2 2 2 1 PHD-finger Acetyltransf_7 PF13508.7 KXH36191.1 - 0.18 12.3 0.0 0.37 11.3 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PHD_2 PF13831.6 KXH36191.1 - 0.53 9.9 1.9 1.4 8.6 1.9 1.8 1 0 0 1 1 1 0 PHD-finger zf-RING_9 PF13901.6 KXH36191.1 - 2.3 8.2 6.0 4.3 7.3 6.0 1.4 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon MWFE PF15879.5 KXH36192.1 - 3.3e-31 107.2 1.0 4.1e-31 106.9 1.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase MWFE subunit ATP_bind_3 PF01171.20 KXH36193.1 - 3.2e-17 62.9 0.0 5.2e-17 62.2 0.0 1.3 1 0 0 1 1 1 1 PP-loop family zn-ribbon_14 PF16503.5 KXH36193.1 - 1.2e-16 59.9 17.7 2.4e-16 58.9 4.2 4.0 4 0 0 4 4 4 2 Zinc-ribbon RecR PF02132.15 KXH36193.1 - 0.022 14.3 0.4 0.022 14.3 0.4 3.0 4 0 0 4 4 4 0 RecR protein GATA PF00320.27 KXH36193.1 - 0.06 13.0 0.6 0.06 13.0 0.6 3.2 3 1 0 3 3 3 0 GATA zinc finger zf-UBR PF02207.20 KXH36193.1 - 0.22 11.7 6.3 2.7 8.2 0.5 2.8 2 0 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) Ribosomal_L7Ae PF01248.26 KXH36194.1 - 1.2e-20 73.1 0.2 2e-20 72.3 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family HLH PF00010.26 KXH36255.1 - 4.1e-12 45.9 1.3 7.7e-12 45.0 1.3 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain ERM PF00769.19 KXH36255.1 - 0.0079 16.0 7.0 0.0079 16.0 7.0 1.6 2 0 0 2 2 2 1 Ezrin/radixin/moesin family GIT1_C PF12205.8 KXH36255.1 - 0.075 13.2 3.3 0.88 9.7 3.1 2.3 1 1 0 1 1 1 0 G protein-coupled receptor kinase-interacting protein 1 C term AAA_28 PF13521.6 KXH36255.1 - 0.12 12.6 0.5 0.46 10.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF5559 PF17714.1 KXH36255.1 - 0.12 12.3 3.4 0.25 11.2 3.4 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5559) SPATA1_C PF15743.5 KXH36255.1 - 6.7 6.8 12.9 13 5.8 12.9 1.5 1 1 0 1 1 1 0 Spermatogenesis-associated C-terminus CLTH PF10607.9 KXH36256.1 - 2.2e-37 128.2 0.0 3.6e-37 127.5 0.0 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 KXH36256.1 - 0.00075 19.4 0.2 0.0026 17.6 0.0 2.0 2 0 0 2 2 2 1 LisH DUF2795 PF11387.8 KXH36256.1 - 0.021 15.0 0.0 1.7 8.9 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2795) AA_kinase PF00696.28 KXH36257.1 - 2.4e-39 135.4 1.3 3.5e-39 134.8 1.3 1.2 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.20 KXH36257.1 - 1.1e-14 54.1 0.4 7.1e-14 51.5 0.0 2.4 2 0 0 2 2 2 1 PUA domain Peptidase_M76 PF09768.9 KXH36258.1 - 6e-68 227.9 1.7 7.4e-68 227.7 1.7 1.1 1 0 0 1 1 1 1 Peptidase M76 family SprT-like PF10263.9 KXH36258.1 - 0.02 14.7 0.5 0.073 12.9 0.1 1.9 2 0 0 2 2 2 0 SprT-like family Peptidase_M91 PF14891.6 KXH36258.1 - 0.067 13.5 0.1 0.12 12.7 0.1 1.4 1 0 0 1 1 1 0 Effector protein Pkinase PF00069.25 KXH36259.1 - 3e-71 239.9 0.0 3.8e-71 239.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXH36259.1 - 1.1e-43 149.5 0.0 1.5e-43 149.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXH36259.1 - 9.9e-07 28.3 0.0 4e-06 26.4 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KXH36259.1 - 0.00064 19.1 0.1 0.001 18.4 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KXH36259.1 - 0.016 14.8 0.0 0.084 12.5 0.0 1.9 1 1 1 2 2 2 0 RIO1 family Haspin_kinase PF12330.8 KXH36259.1 - 0.025 13.5 6.3 0.054 12.4 0.0 2.1 2 0 0 2 2 2 0 Haspin like kinase domain FTA2 PF13095.6 KXH36259.1 - 0.061 13.0 0.0 0.19 11.3 0.0 1.7 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 YrbL-PhoP_reg PF10707.9 KXH36259.1 - 0.085 12.4 0.1 0.24 10.9 0.1 1.8 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL Pkinase_fungal PF17667.1 KXH36259.1 - 0.57 8.9 2.9 0.96 8.1 3.0 1.4 1 1 0 1 1 1 0 Fungal protein kinase TIP41 PF04176.13 KXH36261.1 - 5.3e-69 231.1 0.7 6.6e-69 230.8 0.7 1.1 1 0 0 1 1 1 1 TIP41-like family DEAD PF00270.29 KXH36263.1 - 4.8e-31 107.9 0.1 6.9e-31 107.4 0.1 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXH36263.1 - 1e-18 67.7 0.0 5.2e-18 65.4 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXH36263.1 - 3.9e-06 27.0 0.1 4.3e-05 23.6 0.1 2.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit KH_1 PF00013.29 KXH36265.1 - 4.4e-39 132.1 12.0 5e-16 58.3 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 KXH36265.1 - 1.1e-08 34.8 9.9 0.034 14.0 0.4 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 KXH36265.1 - 1.8e-08 34.1 3.3 0.016 15.1 0.2 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 KXH36265.1 - 0.0001 22.3 5.6 0.25 11.4 0.1 3.3 3 0 0 3 3 3 2 NusA-like KH domain MOEP19 PF16005.5 KXH36265.1 - 0.078 13.0 0.0 19 5.4 0.0 2.3 2 0 0 2 2 2 0 KH-like RNA-binding domain UAA PF08449.11 KXH36266.1 - 1.1e-44 152.9 11.9 1.4e-44 152.5 11.9 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 KXH36266.1 - 0.00021 21.5 33.7 0.038 14.2 13.8 3.6 3 1 0 3 3 3 3 EamA-like transporter family Chromosome_seg PF13889.6 KXH36270.1 - 0.069 13.3 0.9 0.17 12.1 0.9 1.9 1 1 0 1 1 1 0 Chromosome segregation during meiosis Ctr PF04145.15 KXH36271.1 - 1.3e-27 97.3 0.5 1.6e-27 96.9 0.5 1.1 1 0 0 1 1 1 1 Ctr copper transporter family PX PF00787.24 KXH36272.1 - 2.4e-18 66.2 0.1 4.6e-18 65.2 0.1 1.4 1 0 0 1 1 1 1 PX domain Ribosomal_L27A PF00828.19 KXH36273.1 - 3.8e-31 108.4 1.1 5.9e-31 107.8 1.1 1.3 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A adh_short PF00106.25 KXH36274.1 - 1.5e-22 80.0 0.0 2.1e-22 79.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXH36274.1 - 1.3e-11 44.5 0.0 1.7e-11 44.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 3HCDH_N PF02737.18 KXH36274.1 - 0.049 13.5 0.1 0.61 9.9 0.0 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain KR PF08659.10 KXH36274.1 - 0.052 13.5 0.1 0.12 12.3 0.1 1.6 2 0 0 2 2 2 0 KR domain NAD_binding_10 PF13460.6 KXH36274.1 - 0.069 13.0 0.1 0.11 12.4 0.1 1.3 1 0 0 1 1 1 0 NAD(P)H-binding SPDY PF03771.16 KXH36277.1 - 0.039 13.9 0.1 0.082 12.9 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF317) Glyco_transf_90 PF05686.12 KXH36278.1 - 1.5e-17 63.6 0.8 5.7e-13 48.5 0.6 3.0 2 1 0 2 2 2 2 Glycosyl transferase family 90 NACHT PF05729.12 KXH36278.1 - 2.4e-06 27.6 0.0 4.4e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 NACHT domain DUF676 PF05057.14 KXH36278.1 - 0.00022 20.8 0.0 0.00046 19.8 0.0 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 KXH36278.1 - 0.00051 19.8 0.0 0.0011 18.8 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein AAA_16 PF13191.6 KXH36278.1 - 0.0015 18.9 0.0 0.0039 17.6 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KXH36278.1 - 0.0035 17.6 0.0 0.0081 16.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF829 PF05705.14 KXH36278.1 - 0.011 15.7 0.0 0.032 14.1 0.0 1.8 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF829) KAP_NTPase PF07693.14 KXH36278.1 - 0.011 15.0 0.0 0.023 14.0 0.0 1.5 1 0 0 1 1 1 0 KAP family P-loop domain Abhydrolase_6 PF12697.7 KXH36278.1 - 0.013 16.2 3.2 0.041 14.5 0.0 3.2 3 1 0 4 4 3 0 Alpha/beta hydrolase family RNA_helicase PF00910.22 KXH36278.1 - 0.03 14.7 0.1 3.4 8.1 0.0 3.0 3 0 0 3 3 3 0 RNA helicase Hydrolase_4 PF12146.8 KXH36278.1 - 0.071 12.4 0.0 0.2 10.9 0.0 1.7 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Palm_thioest PF02089.15 KXH36278.1 - 0.17 11.7 0.0 0.31 10.8 0.0 1.4 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Cutinase PF01083.22 KXH36278.1 - 0.17 11.8 0.0 0.36 10.8 0.0 1.4 1 0 0 1 1 1 0 Cutinase TctB PF07331.11 KXH36278.1 - 0.29 11.4 12.4 0.59 10.4 2.8 2.9 2 1 1 3 3 2 0 Tripartite tricarboxylate transporter TctB family Cpn60_TCP1 PF00118.24 KXH36279.1 - 3.5e-145 484.4 11.2 4.1e-145 484.2 11.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family CRM1_repeat PF18777.1 KXH36279.1 - 0.098 12.2 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Chromosome region maintenance or exportin repeat DUF5442 PF17514.2 KXH36279.1 - 0.14 12.4 0.2 0.32 11.2 0.2 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5442) eIF2A PF08662.11 KXH36280.1 - 2.6e-38 131.9 2.2 9.3e-35 120.3 0.2 3.6 2 2 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.22 KXH36280.1 - 0.00032 20.5 0.0 0.00072 19.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.32 KXH36280.1 - 0.0076 17.1 1.4 7 7.7 0.0 4.2 4 0 0 4 4 4 1 WD domain, G-beta repeat BofC_C PF08955.10 KXH36280.1 - 0.14 12.2 0.1 31 4.7 0.0 3.4 3 0 0 3 3 3 0 BofC C-terminal domain NIPSNAP PF07978.13 KXH36280.1 - 0.28 11.4 3.1 12 6.2 0.0 3.4 3 0 0 3 3 3 0 NIPSNAP RabGAP-TBC PF00566.18 KXH36281.1 - 3.7e-30 105.2 0.0 6.5e-30 104.4 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SBE2 PF17076.5 KXH36281.1 - 2.6e-08 32.6 0.7 4e-08 32.0 0.7 1.2 1 0 0 1 1 1 1 SBE2, cell-wall formation OPT PF03169.15 KXH36282.1 - 6.5e-168 560.2 49.1 7.5e-168 559.9 49.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein TruB_C_2 PF16198.5 KXH36282.1 - 0.2 11.8 0.6 0.39 10.9 0.2 1.7 2 0 0 2 2 2 0 tRNA pseudouridylate synthase B C-terminal domain zf-LITAF-like PF10601.9 KXH36284.1 - 3.1e-17 62.6 0.2 4.8e-17 62.0 0.2 1.3 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain Sgf11 PF08209.11 KXH36284.1 - 0.013 15.0 3.2 0.043 13.4 0.5 2.4 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) Zn_Tnp_IS1595 PF12760.7 KXH36284.1 - 0.044 13.8 1.4 0.38 10.8 0.1 2.3 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Fungal_trans PF04082.18 KXH36286.1 - 1.5e-12 47.2 0.0 2.6e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH36286.1 - 1.9e-07 31.1 13.1 3.8e-07 30.1 13.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NmrA PF05368.13 KXH36287.1 - 1.8e-15 57.1 0.1 2.5e-15 56.7 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXH36287.1 - 2.4e-13 50.4 0.1 5.8e-13 49.1 0.1 1.7 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KXH36287.1 - 1.7e-06 27.7 0.0 1.5e-05 24.6 0.0 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXH36287.1 - 0.00085 18.4 0.0 0.0013 17.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 KXH36287.1 - 0.0014 18.5 0.1 0.0021 18.0 0.1 1.3 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 KXH36287.1 - 0.0016 17.9 0.0 0.29 10.5 0.1 2.1 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase F420_oxidored PF03807.17 KXH36287.1 - 0.0017 18.9 0.4 0.0037 17.8 0.4 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Glyoxalase_3 PF13468.6 KXH36287.1 - 0.021 14.9 0.0 0.033 14.3 0.0 1.3 1 0 0 1 1 1 0 Glyoxalase-like domain Phage_SSB PF16773.5 KXH36287.1 - 0.028 14.5 0.4 0.091 12.8 0.0 1.9 2 0 0 2 2 2 0 Lactococcus phage single-stranded DNA binding protein Sacchrp_dh_NADP PF03435.18 KXH36287.1 - 0.032 14.5 0.1 0.056 13.7 0.1 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain LpxI_N PF17930.1 KXH36287.1 - 0.041 13.8 0.4 0.091 12.7 0.4 1.5 1 0 0 1 1 1 0 LpxI N-terminal domain Polysacc_synt_2 PF02719.15 KXH36287.1 - 0.054 12.6 0.0 0.092 11.9 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DapB_N PF01113.20 KXH36287.1 - 0.079 13.1 1.4 0.24 11.5 1.4 1.8 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus 4HBT PF03061.22 KXH36288.1 - 1.1e-09 38.5 0.0 1.7e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily Sugar_tr PF00083.24 KXH36290.1 - 6.3e-98 328.6 24.2 7.4e-98 328.3 24.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH36290.1 - 4.9e-18 65.2 53.1 7.5e-16 58.0 28.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Trp_oprn_chp PF09534.10 KXH36290.1 - 0.068 13.0 0.3 1.3 8.8 0.1 2.4 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) LapA_dom PF06305.11 KXH36290.1 - 1.1 9.2 3.8 6.8 6.6 0.1 3.5 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain TadE PF07811.12 KXH36292.1 - 0.029 14.7 0.4 0.029 14.7 0.4 2.0 2 0 0 2 2 2 0 TadE-like protein E1-E2_ATPase PF00122.20 KXH36293.1 - 8e-16 58.1 0.3 1.4e-12 47.5 0.0 2.1 2 0 0 2 2 2 2 E1-E2 ATPase Cation_ATPase_N PF00690.26 KXH36293.1 - 6.9e-12 44.9 0.0 1.1e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus DUF2157 PF09925.9 KXH36293.1 - 6.5e-06 26.0 0.0 7.5e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2157) Fungal_trans PF04082.18 KXH36319.1 - 1.1e-07 31.2 0.6 3e-07 29.7 0.6 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH36319.1 - 1.3e-06 28.4 9.1 1.3e-06 28.4 9.1 2.0 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain EI24 PF07264.11 KXH36320.1 - 2e-09 37.9 21.1 4e-09 37.0 21.1 1.4 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) PalH PF08733.10 KXH36320.1 - 1.8 7.5 4.6 0.78 8.7 2.2 1.5 2 0 0 2 2 2 0 PalH/RIM21 Lip_A_acyltrans PF03279.13 KXH36320.1 - 2.6 7.1 5.2 3.4 6.8 1.5 2.2 2 0 0 2 2 2 0 Bacterial lipid A biosynthesis acyltransferase Ank_2 PF12796.7 KXH36322.1 - 1.5e-34 118.4 1.6 8.5e-12 45.5 0.1 4.7 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXH36322.1 - 2.4e-29 101.0 5.8 1.4e-07 31.7 0.2 6.8 3 2 3 6 6 6 6 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXH36322.1 - 5.8e-28 96.9 0.3 4.2e-09 36.8 0.0 5.3 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 KXH36322.1 - 2e-23 81.7 3.3 0.00023 21.4 0.0 7.1 7 0 0 7 7 7 4 Ankyrin repeat Ank_3 PF13606.6 KXH36322.1 - 2.3e-17 61.3 3.3 0.00014 22.0 0.0 7.0 7 0 0 7 7 7 4 Ankyrin repeat Pkinase PF00069.25 KXH36322.1 - 2.8e-05 23.6 0.0 0.0022 17.4 0.0 3.1 2 1 0 2 2 2 1 Protein kinase domain GIT1_C PF12205.8 KXH36322.1 - 0.091 12.9 0.9 0.29 11.2 0.9 1.9 1 0 0 1 1 1 0 G protein-coupled receptor kinase-interacting protein 1 C term Vps5 PF09325.10 KXH36322.1 - 0.97 8.9 6.4 0.067 12.7 0.5 2.1 2 0 0 2 2 2 0 Vps5 C terminal like Pkinase_Tyr PF07714.17 KXH36323.1 - 1.1e-08 34.7 0.0 2.6e-08 33.5 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXH36323.1 - 3.3e-08 33.2 0.3 5.8e-08 32.4 0.1 1.6 2 0 0 2 2 2 1 Protein kinase domain FANCI_S3 PF14677.6 KXH36323.1 - 0.029 14.1 4.9 0.28 10.9 1.2 3.0 2 1 0 2 2 2 0 FANCI solenoid 3 DUF1840 PF08895.11 KXH36323.1 - 0.045 14.1 0.6 0.81 10.0 0.4 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) UBN_AB PF14075.6 KXH36323.1 - 0.075 12.7 6.4 0.03 14.0 2.3 2.2 2 0 0 2 2 2 0 Ubinuclein conserved middle domain NTNH_C PF08470.10 KXH36323.1 - 0.089 12.7 0.2 0.64 9.9 0.1 2.2 2 0 0 2 2 2 0 Nontoxic nonhaemagglutinin C-terminal FHA PF00498.26 KXH36326.1 - 1.1e-09 38.5 0.2 2.4e-09 37.4 0.1 1.8 1 1 1 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 KXH36326.1 - 1.2e-05 25.5 0.0 2.1e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Helo_like_N PF17111.5 KXH36328.1 - 1.5e-73 246.7 1.8 4.9e-70 235.1 0.1 2.2 2 0 0 2 2 2 2 Fungal N-terminal domain of STAND proteins DASH_Dad2 PF08654.10 KXH36328.1 - 0.022 15.1 2.9 0.2 12.1 0.3 2.7 2 0 0 2 2 2 0 DASH complex subunit Dad2 SCO1-SenC PF02630.14 KXH36328.1 - 0.086 12.8 0.2 0.23 11.4 0.0 1.8 2 0 0 2 2 2 0 SCO1/SenC DUF2937 PF11157.8 KXH36328.1 - 0.1 12.3 4.8 0.15 11.7 0.3 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2937) DUF148 PF02520.17 KXH36328.1 - 0.21 11.7 2.0 1 9.5 0.0 2.9 1 1 1 3 3 3 0 Domain of unknown function DUF148 IFT57 PF10498.9 KXH36328.1 - 0.3 10.0 3.6 0.65 8.9 0.5 2.2 1 1 0 2 2 2 0 Intra-flagellar transport protein 57 COG2 PF06148.11 KXH36328.1 - 0.42 10.7 7.7 7.5 6.6 0.3 4.0 2 1 2 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 SKA1 PF07160.12 KXH36328.1 - 3.5 7.4 5.3 1.3 8.8 0.7 2.3 2 1 1 3 3 3 0 Spindle and kinetochore-associated protein 1 Seryl_tRNA_N PF02403.22 KXH36328.1 - 5.6 7.2 6.3 39 4.5 0.0 3.6 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain APH PF01636.23 KXH36329.1 - 2.4e-08 34.2 0.4 2.9e-05 24.1 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 KXH36329.1 - 0.00011 21.6 0.2 0.0012 18.3 0.0 2.1 1 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KXH36329.1 - 0.014 15.0 0.0 0.019 14.5 0.0 1.3 1 0 0 1 1 1 0 RIO1 family WaaY PF06176.11 KXH36329.1 - 0.041 13.5 0.0 0.06 13.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Pkinase PF00069.25 KXH36329.1 - 0.17 11.2 0.0 0.25 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain CoatB PF10389.9 KXH36332.1 - 1.3 8.9 6.5 0.83 9.5 3.9 1.9 2 0 0 2 2 2 0 Bacteriophage coat protein B tRNA-synt_1c PF00749.21 KXH36337.1 - 3.9e-102 341.4 0.0 5.6e-102 340.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 KXH36337.1 - 3.1e-32 111.9 0.1 3.9e-31 108.3 0.0 2.6 3 0 0 3 3 3 1 tRNA synthetases class I (E and Q), anti-codon binding domain Hc1 PF07432.13 KXH36337.1 - 0.12 12.7 12.1 0.37 11.2 12.1 1.8 1 0 0 1 1 1 0 Histone H1-like protein Hc1 Macro PF01661.21 KXH36338.1 - 4.4e-24 84.8 0.0 9.8e-24 83.7 0.0 1.6 2 0 0 2 2 2 1 Macro domain Peptidase_S41 PF03572.18 KXH36339.1 - 6.1e-05 22.6 0.0 0.00011 21.8 0.0 1.6 1 0 0 1 1 1 1 Peptidase family S41 NACHT PF05729.12 KXH36340.1 - 1.6e-07 31.4 0.0 9.6e-07 28.9 0.0 2.4 2 1 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 KXH36340.1 - 2.4e-05 24.8 0.1 0.00023 21.6 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KXH36340.1 - 4.1e-05 23.9 0.0 0.00012 22.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KXH36340.1 - 0.004 16.9 0.1 0.009 15.7 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 KXH36340.1 - 0.0044 17.5 0.4 0.0044 17.5 0.4 2.2 1 1 1 2 2 2 1 AAA domain ABC_tran PF00005.27 KXH36340.1 - 0.019 15.5 0.0 0.073 13.6 0.0 1.9 1 0 0 1 1 1 0 ABC transporter AAA PF00004.29 KXH36340.1 - 0.022 15.2 0.0 0.22 11.9 0.0 2.6 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF5644 PF18712.1 KXH36340.1 - 0.051 13.6 0.0 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5644) NTPase_1 PF03266.15 KXH36340.1 - 0.058 13.3 0.2 0.17 11.8 0.1 1.8 2 0 0 2 2 2 0 NTPase AAA_30 PF13604.6 KXH36340.1 - 0.07 12.8 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KXH36340.1 - 0.098 13.2 0.2 0.33 11.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 KXH36340.1 - 0.13 11.5 0.1 0.34 10.1 0.1 1.7 1 0 0 1 1 1 0 NB-ARC domain ATPase_2 PF01637.18 KXH36340.1 - 0.14 12.0 0.9 1.5 8.7 0.0 3.1 3 1 0 3 3 3 0 ATPase domain predominantly from Archaea DUF4404 PF14357.6 KXH36340.1 - 0.94 10.2 2.9 2.4 8.9 0.6 2.9 2 2 0 2 2 2 0 Domain of unknown function (DUF4404) Lipocalin_5 PF13924.6 KXH36341.1 - 9.8e-28 96.7 0.0 1.1e-27 96.6 0.0 1.0 1 0 0 1 1 1 1 Lipocalin-like domain AA_permease PF00324.21 KXH36342.1 - 5.4e-25 87.9 8.1 1.2e-16 60.4 0.0 2.5 2 1 0 2 2 2 2 Amino acid permease AA_permease_2 PF13520.6 KXH36342.1 - 3.5e-13 49.2 15.1 3.7e-12 45.8 15.1 2.1 1 1 0 1 1 1 1 Amino acid permease CBM_25 PF03423.13 KXH36342.1 - 0.051 13.8 0.1 0.1 12.9 0.1 1.4 1 0 0 1 1 1 0 Carbohydrate binding domain (family 25) DUF1218 PF06749.12 KXH36342.1 - 1.6 9.3 7.0 1.6 9.3 0.6 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1218) Pkinase PF00069.25 KXH36345.1 - 6e-23 81.5 0.0 2.7e-22 79.4 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXH36345.1 - 1.1e-14 54.3 0.0 2.6e-09 36.8 0.0 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 KXH36345.1 - 0.019 14.0 0.1 0.034 13.1 0.1 1.4 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Peptidase_M14 PF00246.24 KXH36346.1 - 8.1e-15 55.4 0.0 1.3e-14 54.7 0.0 1.3 1 0 0 1 1 1 1 Zinc carboxypeptidase AstE_AspA PF04952.14 KXH36346.1 - 0.018 14.1 0.2 0.04 13.0 0.0 1.6 2 0 0 2 2 2 0 Succinylglutamate desuccinylase / Aspartoacylase family Glyco_hydro_43 PF04616.14 KXH36347.1 - 2.5e-74 250.2 0.1 3.4e-74 249.8 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 KXH36347.1 - 1.1e-11 44.8 0.0 1.8e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain Adenylsucc_synt PF00709.21 KXH36348.1 - 8.5e-165 548.7 0.0 1.2e-164 548.3 0.0 1.2 1 0 0 1 1 1 1 Adenylosuccinate synthetase CFEM PF05730.11 KXH36349.1 - 1.1e-08 35.1 6.2 1.5e-08 34.6 6.2 1.2 1 0 0 1 1 1 1 CFEM domain Sugar_tr PF00083.24 KXH36351.1 - 8.3e-102 341.4 17.5 9.4e-102 341.2 17.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH36351.1 - 6.8e-16 58.1 26.2 6.8e-16 58.1 26.2 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_holin_3_2 PF04550.12 KXH36351.1 - 0.012 16.1 0.6 0.045 14.3 0.6 2.0 1 0 0 1 1 1 0 Phage holin family 2 Exo_endo_phos PF03372.23 KXH36351.1 - 0.23 10.9 0.0 4.8 6.6 0.0 2.2 2 0 0 2 2 2 0 Endonuclease/Exonuclease/phosphatase family adh_short_C2 PF13561.6 KXH36352.1 - 3e-57 193.9 3.6 3.6e-57 193.6 3.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXH36352.1 - 8.3e-44 149.4 3.5 1e-43 149.1 3.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXH36352.1 - 8.7e-12 45.3 3.1 1.2e-11 44.8 3.1 1.1 1 0 0 1 1 1 1 KR domain DUF2188 PF09954.9 KXH36352.1 - 0.1 12.7 2.6 0.16 12.2 0.3 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2188) Epimerase PF01370.21 KXH36352.1 - 0.13 11.7 1.3 0.28 10.6 1.3 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Melibiase_2 PF16499.5 KXH36353.1 - 5.6e-39 134.0 1.1 1.1e-38 133.0 1.1 1.5 1 1 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 KXH36353.1 - 1.8e-15 56.8 3.0 2.2e-15 56.5 1.4 2.1 2 0 0 2 2 2 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 KXH36353.1 - 0.0017 17.4 0.0 0.0031 16.5 0.0 1.3 1 0 0 1 1 1 1 Melibiase F-box-like PF12937.7 KXH36354.1 - 0.00044 20.1 0.4 0.0043 16.9 0.1 2.5 2 0 0 2 2 2 1 F-box-like UBM PF14377.6 KXH36354.1 - 0.13 11.8 0.2 0.33 10.5 0.2 1.8 1 0 0 1 1 1 0 Ubiquitin binding region LRR_4 PF12799.7 KXH36354.1 - 0.36 11.3 8.2 4 8.0 0.3 4.5 5 1 1 6 6 6 0 Leucine Rich repeats (2 copies) LEA_4 PF02987.16 KXH36355.1 - 0.12 12.5 0.6 0.21 11.7 0.6 1.3 1 0 0 1 1 1 0 Late embryogenesis abundant protein FAD_binding_3 PF01494.19 KXH36356.1 - 9.1e-76 255.4 0.0 1.4e-75 254.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 KXH36356.1 - 2.2e-41 141.7 0.1 3.9e-41 140.9 0.1 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox_2 PF07992.14 KXH36356.1 - 0.00044 19.6 0.0 0.016 14.5 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXH36356.1 - 0.001 19.6 0.0 0.0052 17.3 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXH36356.1 - 0.027 14.7 0.0 0.07 13.4 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXH36356.1 - 0.038 13.6 0.9 2.9 7.4 0.2 2.3 1 1 0 2 2 2 0 FAD dependent oxidoreductase XdhC_C PF13478.6 KXH36356.1 - 0.038 14.5 0.0 0.078 13.5 0.0 1.5 1 0 0 1 1 1 0 XdhC Rossmann domain HI0933_like PF03486.14 KXH36356.1 - 0.053 12.2 0.0 0.09 11.5 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein UDPG_MGDP_dh_N PF03721.14 KXH36356.1 - 0.1 12.2 0.0 0.32 10.5 0.0 1.8 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Thi4 PF01946.17 KXH36356.1 - 0.13 11.4 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.12 KXH36356.1 - 0.16 11.0 0.0 1 8.3 0.0 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein MTCP1 PF08991.10 KXH36357.1 - 0.11 12.7 0.0 0.2 11.9 0.0 1.3 1 0 0 1 1 1 0 Mature-T-Cell Proliferation I type Rick_17kDa_Anti PF05433.15 KXH36358.1 - 9.6e-05 22.2 6.2 0.02 14.7 0.7 2.4 2 0 0 2 2 2 2 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.6 KXH36358.1 - 0.0055 16.7 2.5 0.46 10.5 0.0 2.3 2 0 0 2 2 2 2 Glycine zipper DUF2530 PF10745.9 KXH36358.1 - 0.028 14.6 1.3 1.8 8.9 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) MFS_1 PF07690.16 KXH36359.1 - 3.9e-33 114.8 60.7 8.8e-24 84.1 29.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3681 PF12442.8 KXH36359.1 - 6.3 7.3 16.0 0.12 12.9 2.1 4.1 2 2 1 3 3 3 0 Protein of unknown function (DUF3681) LCM PF04072.14 KXH36360.1 - 2e-20 73.5 0.0 3e-20 73.0 0.0 1.2 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Kelch_4 PF13418.6 KXH36360.1 - 3.8e-09 36.4 1.2 3.3e-08 33.4 0.0 3.0 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_3 PF13415.6 KXH36360.1 - 5e-05 23.5 0.1 0.082 13.2 0.0 3.8 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_6 PF13964.6 KXH36360.1 - 0.0099 16.1 0.1 25 5.4 0.0 3.6 3 0 0 3 3 3 1 Kelch motif XdhC_CoxI PF02625.16 KXH36360.1 - 0.07 13.3 0.0 20 5.5 0.0 2.5 2 0 0 2 2 2 0 XdhC and CoxI family WD40 PF00400.32 KXH36361.1 - 0.0017 19.1 1.9 0.54 11.2 0.0 4.2 5 1 0 5 5 5 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXH36361.1 - 0.0025 18.1 0.0 0.63 10.4 0.0 3.8 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Hira PF07569.11 KXH36361.1 - 0.069 12.9 0.0 0.8 9.4 0.0 2.3 2 0 0 2 2 2 0 TUP1-like enhancer of split LCAT PF02450.15 KXH36362.1 - 4.6e-109 365.2 0.1 6.6e-109 364.6 0.1 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.7 KXH36362.1 - 0.0033 18.1 0.4 0.016 15.8 0.1 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family DUF1778 PF08681.11 KXH36362.1 - 0.1 12.5 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1778) Chs7 PF12271.8 KXH36364.1 - 2.9e-111 371.4 9.1 3.3e-111 371.3 9.1 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone Herpes_UL20 PF04544.12 KXH36364.1 - 0.016 15.6 0.4 0.016 15.6 0.4 2.4 1 1 2 3 3 3 0 Herpesvirus egress protein UL20 DUF347 PF03988.12 KXH36364.1 - 0.34 11.1 0.0 0.34 11.1 0.0 5.1 5 2 0 5 5 5 0 Repeat of Unknown Function (DUF347) Cytochrom_B561 PF03188.16 KXH36365.1 - 1.4e-17 64.1 2.3 1.4e-17 64.1 2.3 1.6 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 DUF4006 PF13179.6 KXH36365.1 - 0.0023 17.8 0.1 0.32 10.9 0.1 2.7 2 0 0 2 2 2 1 Family of unknown function (DUF4006) DUF4079 PF13301.6 KXH36365.1 - 0.0077 16.4 14.0 1.4 9.1 0.8 3.2 1 1 2 3 3 3 3 Protein of unknown function (DUF4079) Ni_hydr_CYTB PF01292.20 KXH36365.1 - 0.046 13.3 11.7 0.3 10.7 6.8 2.5 1 1 1 2 2 2 0 Prokaryotic cytochrome b561 DUF4271 PF14093.6 KXH36365.1 - 0.078 12.9 5.0 0.047 13.6 3.5 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4271) DUF2347 PF09804.9 KXH36365.1 - 0.13 11.8 0.1 0.18 11.4 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) LrgA PF03788.14 KXH36365.1 - 1.2 9.1 9.0 0.084 12.8 0.6 2.8 2 2 1 3 3 3 0 LrgA family PepSY_TM PF03929.16 KXH36365.1 - 6.5 6.3 11.2 0.94 9.1 5.8 2.2 1 1 0 2 2 2 0 PepSY-associated TM region Allantoicase PF03561.15 KXH36366.1 - 1.3e-96 320.3 0.1 4e-47 159.8 0.0 2.1 2 0 0 2 2 2 2 Allantoicase repeat DIL PF01843.19 KXH36367.1 - 1.7e-32 111.7 0.3 3.4e-32 110.8 0.3 1.5 1 0 0 1 1 1 1 DIL domain Ank_2 PF12796.7 KXH36367.1 - 1.3e-18 67.3 0.0 2.3e-11 44.1 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXH36367.1 - 6.2e-11 42.6 0.0 5.1e-06 26.9 0.0 3.8 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 KXH36367.1 - 5.5e-09 36.1 0.1 0.0052 17.2 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 KXH36367.1 - 1.5e-08 34.7 0.0 5.6e-06 26.5 0.0 2.7 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXH36367.1 - 2.3e-06 27.5 0.0 0.16 12.6 0.0 3.9 3 0 0 3 3 3 2 Ankyrin repeat RabGAP-TBC PF00566.18 KXH36369.1 - 3.3e-33 115.2 0.0 4.7e-33 114.6 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Ribosomal_S13 PF00416.22 KXH36369.1 - 0.16 12.3 0.2 0.34 11.3 0.2 1.5 1 0 0 1 1 1 0 Ribosomal protein S13/S18 FSA_C PF10479.9 KXH36369.1 - 3.2 5.8 8.7 5.4 5.0 8.7 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Ppx-GppA PF02541.16 KXH36375.1 - 1.4e-26 93.6 0.0 4.3e-25 88.7 0.0 2.1 1 1 0 1 1 1 1 Ppx/GppA phosphatase family HET PF06985.11 KXH36376.1 - 4.2e-30 105.0 0.4 7.5e-30 104.2 0.4 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.16 KXH36377.1 - 2.1e-30 105.9 36.5 2.1e-30 105.9 36.5 1.8 1 1 0 2 2 2 1 Major Facilitator Superfamily Peptidase_M19 PF01244.21 KXH36378.1 - 1.6e-101 339.7 0.0 1.8e-101 339.5 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) IL34 PF15036.6 KXH36379.1 - 0.019 15.0 0.0 0.73 9.9 0.0 2.2 2 0 0 2 2 2 0 Interleukin 34 CYTL1 PF15153.6 KXH36379.1 - 0.042 13.8 0.2 0.18 11.8 0.1 2.0 3 0 0 3 3 3 0 Cytokine-like protein 1 Methyltransf_23 PF13489.6 KXH36516.1 - 0.029 14.2 0.0 0.031 14.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 KXH36517.1 - 1.4e-21 77.0 0.0 2.1e-21 76.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH36517.1 - 6.4e-11 42.8 0.0 1.3e-10 41.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH36517.1 - 2.2e-09 37.3 0.0 1.7e-08 34.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH36517.1 - 1.5e-08 35.2 0.0 1e-07 32.6 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH36517.1 - 7e-07 29.8 0.0 1.5e-06 28.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KXH36517.1 - 0.0026 17.2 0.0 0.0038 16.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.19 KXH36517.1 - 0.021 14.9 0.0 0.057 13.5 0.0 1.4 1 1 0 1 1 1 0 FtsJ-like methyltransferase MTS PF05175.14 KXH36517.1 - 0.031 13.8 0.0 0.08 12.5 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase small domain Ubie_methyltran PF01209.18 KXH36517.1 - 0.07 12.5 0.0 0.84 8.9 0.0 2.2 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family R3H PF01424.22 KXH36518.1 - 6.6e-16 58.0 0.2 1.2e-15 57.2 0.2 1.5 1 0 0 1 1 1 1 R3H domain zf-NF-X1 PF01422.17 KXH36518.1 - 6.1e-06 26.2 50.2 5.2e-05 23.2 12.4 13.6 14 1 0 14 14 14 7 NF-X1 type zinc finger Bac_surface_Ag PF01103.23 KXH36520.1 - 7.1e-39 134.2 0.5 1e-38 133.7 0.5 1.2 1 0 0 1 1 1 1 Surface antigen FAD_binding_4 PF01565.23 KXH36521.1 - 3.4e-21 75.4 6.9 5.4e-21 74.8 6.9 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KXH36521.1 - 3.9e-07 30.1 0.0 7.5e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Berberine and berberine like TMEM135_C_rich PF15982.5 KXH36523.1 - 0.0045 17.6 0.2 0.0094 16.6 0.2 1.5 1 0 0 1 1 1 1 N-terminal cysteine-rich region of Transmembrane protein 135 Sugar_tr PF00083.24 KXH36524.1 - 3.4e-102 342.6 19.4 3.9e-102 342.4 19.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH36524.1 - 1.1e-29 103.5 41.3 8.1e-27 94.1 20.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_5 PF05631.14 KXH36524.1 - 0.00012 21.1 1.3 0.00012 21.1 1.3 1.6 2 0 0 2 2 2 1 Sugar-tranasporters, 12 TM Glyco_transf_15 PF01793.16 KXH36525.1 - 4.9e-95 318.5 7.2 5.5e-94 315.0 7.2 1.9 1 1 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Pex26 PF07163.12 KXH36525.1 - 0.2 10.9 0.1 0.29 10.4 0.1 1.1 1 0 0 1 1 1 0 Pex26 protein ILVD_EDD PF00920.21 KXH36526.1 - 3.1e-206 686.0 0.5 3.6e-206 685.8 0.5 1.0 1 0 0 1 1 1 1 Dehydratase family Myb_DNA-binding PF00249.31 KXH36527.1 - 0.0002 21.5 0.1 0.017 15.3 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain R3H PF01424.22 KXH36533.1 - 8.9e-10 38.4 0.3 1.7e-09 37.5 0.3 1.4 1 0 0 1 1 1 1 R3H domain RRM_1 PF00076.22 KXH36533.1 - 1.4e-05 24.8 0.0 4.2e-05 23.3 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_2 PF04059.12 KXH36533.1 - 0.061 13.5 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif 2 Mre11_DNA_bind PF04152.14 KXH36535.1 - 1.2e-53 181.9 0.4 1.2e-53 181.9 0.4 2.0 2 0 0 2 2 2 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 KXH36535.1 - 1.1e-15 58.7 2.3 2.3e-15 57.7 2.3 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KXH36535.1 - 0.00029 21.0 0.0 0.0022 18.2 0.0 2.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain eIF3_subunit PF08597.10 KXH36535.1 - 3.7 7.4 23.5 1.9 8.3 6.4 2.5 1 1 1 2 2 2 0 Translation initiation factor eIF3 subunit Peptidase_M43 PF05572.13 KXH36536.1 - 5e-17 62.2 1.9 3.1e-16 59.6 0.2 2.1 2 0 0 2 2 2 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.6 KXH36536.1 - 1.1e-05 26.0 0.0 2.1e-05 25.0 0.0 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 KXH36536.1 - 3.4e-05 24.1 2.9 9.6e-05 22.6 3.0 1.7 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 KXH36536.1 - 8.5e-05 22.3 0.1 0.00013 21.7 0.1 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 KXH36536.1 - 0.00019 21.4 1.6 0.0011 18.9 0.2 2.1 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 KXH36536.1 - 0.0055 16.6 0.0 0.0083 16.0 0.0 1.4 1 1 0 1 1 1 1 Matrixin Peptidase_M54 PF07998.11 KXH36536.1 - 0.015 15.3 0.0 0.025 14.5 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M54 DUF4953 PF16313.5 KXH36536.1 - 0.015 14.5 0.0 0.026 13.7 0.0 1.3 1 0 0 1 1 1 0 Met-zincin Peptidase_M66 PF10462.9 KXH36536.1 - 0.024 13.6 2.3 0.033 13.1 2.0 1.5 1 1 0 1 1 1 0 Peptidase M66 Metallopep PF12044.8 KXH36536.1 - 0.27 9.8 1.5 0.36 9.4 0.6 1.6 2 0 0 2 2 2 0 Putative peptidase family Beta-lactamase PF00144.24 KXH36537.1 - 6.9e-26 91.3 0.2 1.2e-25 90.4 0.2 1.3 1 0 0 1 1 1 1 Beta-lactamase Peptidase_M28 PF04389.17 KXH36538.1 - 3.6e-38 131.3 0.0 4.9e-38 130.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KXH36538.1 - 6.3e-09 35.8 0.2 1.2e-08 34.9 0.2 1.6 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Nicastrin PF05450.15 KXH36538.1 - 0.017 14.6 0.1 0.32 10.4 0.0 2.2 2 0 0 2 2 2 0 Nicastrin Colipase PF01114.18 KXH36539.1 - 0.12 12.0 3.9 0.21 11.3 3.9 1.3 1 0 0 1 1 1 0 Colipase, N-terminal domain Fungal_trans PF04082.18 KXH36541.1 - 5.5e-11 42.0 0.0 9.2e-11 41.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 KXH36543.1 - 8.3e-16 57.8 31.5 3.8e-12 45.8 12.4 2.3 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH36543.1 - 2.1e-06 26.9 3.7 2.1e-06 26.9 3.7 2.6 2 1 1 3 3 3 1 Sugar (and other) transporter SH3_6 PF12913.7 KXH36543.1 - 0.03 13.9 0.1 0.068 12.7 0.1 1.6 1 0 0 1 1 1 0 SH3 domain (SH3b1 type) ADH_N PF08240.12 KXH36544.1 - 2e-05 24.4 0.0 3.7e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 KXH36544.1 - 0.079 12.9 0.0 0.28 11.1 0.0 1.9 2 0 0 2 2 2 0 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 KXH36544.1 - 0.23 11.5 1.0 5.6 7.0 0.0 2.2 2 0 0 2 2 2 0 Zinc-binding dehydrogenase FMO-like PF00743.19 KXH36545.1 - 3.5e-10 38.9 0.0 1.7e-09 36.7 0.0 1.8 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KXH36545.1 - 7.9e-10 38.4 0.0 2.1e-07 30.4 0.0 2.1 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KXH36545.1 - 7.9e-10 38.5 0.0 4.4e-09 36.0 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXH36545.1 - 7.3e-06 26.1 0.0 3.5e-05 23.9 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXH36545.1 - 1.1e-05 24.8 0.0 7.5e-05 22.1 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase hSac2 PF12456.8 KXH36545.1 - 0.023 14.4 0.0 0.91 9.3 0.0 2.3 2 0 0 2 2 2 0 Inositol phosphatase Thi4 PF01946.17 KXH36545.1 - 0.028 13.7 0.0 0.074 12.3 0.0 1.7 2 0 0 2 2 2 0 Thi4 family NAD_binding_9 PF13454.6 KXH36545.1 - 0.037 14.0 0.0 0.46 10.4 0.0 2.7 2 1 0 2 2 2 0 FAD-NAD(P)-binding Kinesin PF00225.23 KXH36547.1 - 5.6e-54 183.3 0.0 8e-54 182.8 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KXH36547.1 - 2.6e-07 30.7 0.0 4.5e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Microtubule binding AAA_16 PF13191.6 KXH36547.1 - 0.024 15.0 0.1 0.066 13.6 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain COesterase PF00135.28 KXH36548.1 - 4.5e-92 309.5 0.0 5.6e-92 309.2 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXH36548.1 - 5.8e-08 32.8 0.0 1.4e-06 28.4 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KXH36548.1 - 0.0054 16.2 0.0 0.0095 15.4 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family PAPS_reduct PF01507.19 KXH36549.1 - 1.1e-29 103.7 0.0 6.9e-21 75.0 0.0 2.2 1 1 1 2 2 2 2 Phosphoadenosine phosphosulfate reductase family DegS PF05384.11 KXH36549.1 - 0.17 11.4 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 Sensor protein DegS YqfD PF06898.11 KXH36550.1 - 0.22 10.3 0.2 0.39 9.5 0.2 1.3 1 0 0 1 1 1 0 Putative stage IV sporulation protein YqfD adh_short PF00106.25 KXH36552.1 - 7.7e-39 133.2 0.1 9.6e-39 132.9 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXH36552.1 - 2.2e-26 92.8 0.1 3e-26 92.4 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH36552.1 - 8.8e-07 29.0 0.1 1.4e-06 28.4 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXH36552.1 - 0.00014 21.4 0.1 0.00032 20.2 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 KXH36552.1 - 0.00032 20.1 0.0 0.00039 19.9 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Polysacc_synt_2 PF02719.15 KXH36552.1 - 0.00052 19.3 0.0 0.00086 18.5 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 KXH36552.1 - 0.00077 19.4 0.1 0.00094 19.1 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 KXH36552.1 - 0.03 13.4 0.0 0.042 13.0 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain NmrA PF05368.13 KXH36552.1 - 0.094 12.3 0.3 0.17 11.4 0.3 1.4 2 0 0 2 2 2 0 NmrA-like family RHS_repeat PF05593.14 KXH36553.1 - 0.21 12.2 0.6 0.45 11.1 0.6 1.5 1 0 0 1 1 1 0 RHS Repeat DUF4863 PF16155.5 KXH36555.1 - 3e-70 235.0 0.0 3.5e-70 234.8 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4863) DUF1737 PF08410.10 KXH36555.1 - 0.34 10.8 1.5 0.6 10.0 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1737) Hydrolase_4 PF12146.8 KXH36556.1 - 5.4e-11 42.2 0.1 1.6e-06 27.6 0.1 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KXH36556.1 - 2.6e-08 33.8 0.1 0.00081 19.1 0.1 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXH36556.1 - 5.7e-08 33.6 3.1 1.1e-07 32.8 3.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family LIP PF03583.14 KXH36556.1 - 0.0014 18.0 0.3 0.088 12.1 0.2 2.1 2 0 0 2 2 2 1 Secretory lipase Peptidase_S9 PF00326.21 KXH36556.1 - 0.01 15.3 0.1 3.5 7.1 0.3 2.7 3 0 0 3 3 3 0 Prolyl oligopeptidase family DLH PF01738.18 KXH36556.1 - 0.061 12.9 0.0 9.5 5.7 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family DUF3425 PF11905.8 KXH36557.1 - 1.2e-18 67.2 0.2 4.4e-18 65.4 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3425) Aldo_ket_red PF00248.21 KXH36558.1 - 1.5e-42 145.9 0.0 1.1e-41 143.0 0.0 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family UTP15_C PF09384.10 KXH36559.1 - 0.081 12.6 0.6 0.16 11.6 0.2 1.7 2 0 0 2 2 2 0 UTP15 C terminal FliJ PF02050.16 KXH36559.1 - 0.21 11.8 2.4 2.5 8.3 0.2 2.4 2 0 0 2 2 2 0 Flagellar FliJ protein MFS_1 PF07690.16 KXH36560.1 - 4e-35 121.4 47.6 1.3e-34 119.7 46.6 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH36560.1 - 3.5e-11 42.6 18.1 4.1e-11 42.4 5.4 2.5 2 0 0 2 2 2 2 Sugar (and other) transporter ORC6 PF05460.13 KXH36560.1 - 0.059 12.6 0.2 0.076 12.3 0.2 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) RdRP PF05183.12 KXH36561.1 - 2.6e-166 554.7 0.0 3.6e-166 554.3 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase Abhydrolase_1 PF00561.20 KXH36562.1 - 2.4e-13 50.3 0.0 6.3e-13 49.0 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXH36562.1 - 1.9e-11 45.0 0.2 3.5e-11 44.1 0.2 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.14 KXH36562.1 - 1.4e-10 40.3 0.0 2e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 Ndr family Hydrolase_4 PF12146.8 KXH36562.1 - 2.8e-06 26.8 0.0 1.1e-05 24.8 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 EthD PF07110.11 KXH36562.1 - 4.8e-05 24.4 0.2 0.29 12.3 0.0 2.9 2 1 0 2 2 2 2 EthD domain DUF4286 PF14114.6 KXH36562.1 - 0.00011 22.6 0.0 0.38 11.3 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4286) Esterase PF00756.20 KXH36562.1 - 0.13 11.9 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Como_LCP PF02247.16 KXH36562.1 - 0.13 10.8 0.0 0.21 10.2 0.0 1.2 1 0 0 1 1 1 0 Large coat protein Glyco_hydro_61 PF03443.14 KXH36563.1 - 9.8e-63 211.8 0.8 1.3e-62 211.4 0.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Serglycin PF04360.12 KXH36563.1 - 0.0016 18.4 4.0 0.0031 17.5 4.0 1.4 1 0 0 1 1 1 1 Serglycin Zn_clus PF00172.18 KXH36564.1 - 3.9e-06 26.9 11.5 6.3e-06 26.2 11.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HypA PF01155.19 KXH36564.1 - 1.3 9.1 4.7 15 5.6 5.1 2.2 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Sugar_tr PF00083.24 KXH36568.1 - 1.5e-70 238.4 18.9 1.7e-70 238.2 18.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH36568.1 - 9.4e-11 41.2 18.7 9.4e-11 41.2 18.7 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Cas6b_C PF17262.2 KXH36568.1 - 0.049 13.7 0.1 0.29 11.2 0.0 2.1 2 0 0 2 2 2 0 Cas6b C-terminal domain Sulfatase PF00884.23 KXH36569.1 - 3.5e-71 240.1 0.0 4.6e-71 239.7 0.0 1.1 1 0 0 1 1 1 1 Sulfatase DUF4976 PF16347.5 KXH36569.1 - 0.00011 22.4 0.1 0.00031 21.0 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4976) DUF229 PF02995.17 KXH36569.1 - 0.0025 16.5 0.0 0.0051 15.5 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF229) Phosphodiest PF01663.22 KXH36569.1 - 0.0037 16.9 0.1 1.2 8.6 0.0 2.3 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.6 KXH36569.1 - 0.015 16.1 0.9 0.37 11.5 0.5 2.6 2 1 0 2 2 2 0 C-terminal region of aryl-sulfatase TILa PF12714.7 KXH36571.1 - 0.16 12.0 0.6 0.22 11.5 0.6 1.2 1 0 0 1 1 1 0 TILa domain NKAP PF15692.5 KXH36572.1 - 0.15 12.8 0.4 0.37 11.5 0.4 1.6 1 0 0 1 1 1 0 NF-kappa-B-activating protein DUF2235 PF09994.9 KXH36573.1 - 8.6e-38 130.3 0.0 1.4e-37 129.6 0.0 1.3 1 1 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_6 PF12697.7 KXH36573.1 - 0.1 13.2 0.1 0.12 12.9 0.1 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXH36573.1 - 0.14 11.8 0.1 0.19 11.3 0.1 1.3 1 1 0 1 1 1 0 alpha/beta hydrolase fold FSH1 PF03959.13 KXH36573.1 - 0.21 11.2 0.1 0.48 10.0 0.0 1.5 2 0 0 2 2 2 0 Serine hydrolase (FSH1) RTA1 PF04479.13 KXH36574.1 - 2e-46 158.2 4.7 2e-46 158.2 4.7 1.6 2 0 0 2 2 2 1 RTA1 like protein p450 PF00067.22 KXH36574.1 - 1.3e-35 123.1 0.0 2.9e-35 121.9 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 DUF2062 PF09835.9 KXH36574.1 - 0.11 12.4 6.0 0.16 11.8 4.2 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2062) NARP1 PF12569.8 KXH36574.1 - 0.58 9.0 9.3 0.58 9.0 7.2 1.8 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 Iso_dh PF00180.20 KXH36575.1 - 6.9e-107 357.6 0.0 7.9e-107 357.4 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Aminotran_4 PF01063.19 KXH36576.1 - 2.7e-21 76.5 0.0 3.5e-21 76.1 0.0 1.2 1 0 0 1 1 1 1 Amino-transferase class IV DUF2937 PF11157.8 KXH36576.1 - 0.0026 17.5 0.1 0.01 15.6 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2937) Aconitase PF00330.20 KXH36577.1 - 1.9e-76 257.9 0.2 1.3e-74 251.9 0.2 2.2 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KXH36577.1 - 3.6e-11 43.5 0.0 7e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Aconitase_2_N PF06434.13 KXH36577.1 - 0.00027 20.7 0.0 0.00044 19.9 0.0 1.3 1 0 0 1 1 1 1 Aconitate hydratase 2 N-terminus Ank_2 PF12796.7 KXH36578.1 - 1.9e-19 70.0 1.1 6.6e-15 55.5 0.2 2.5 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXH36578.1 - 7.2e-16 56.7 0.1 0.00029 21.0 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 KXH36578.1 - 1.5e-15 57.3 0.1 2.2e-09 37.7 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KXH36578.1 - 6.3e-15 54.9 3.2 5.5e-06 26.6 0.9 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 KXH36578.1 - 3.6e-12 46.3 0.4 7.1e-07 29.4 0.1 2.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Rrn6 PF10214.9 KXH36578.1 - 0.076 11.5 2.3 0.1 11.1 2.3 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Pap_E4 PF02711.14 KXH36578.1 - 0.091 13.7 2.2 6.5 7.8 1.8 2.6 2 1 0 2 2 2 0 E4 protein DUF4674 PF15719.5 KXH36578.1 - 2.2 8.3 4.7 3 7.9 4.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4674) p450 PF00067.22 KXH36579.1 - 2.9e-52 178.0 0.0 3.8e-52 177.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Polysacc_deac_1 PF01522.21 KXH36580.1 - 3.3e-12 46.4 0.0 4.8e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 KXH36580.1 - 3.6e-06 26.8 0.0 7.1e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) HMGL-like PF00682.19 KXH36581.1 - 7.2e-65 219.2 0.0 1.4e-64 218.2 0.0 1.4 1 0 0 1 1 1 1 HMGL-like Aminotran_5 PF00266.19 KXH36581.1 - 4.6e-52 177.2 0.0 7.7e-52 176.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 KXH36581.1 - 8.5e-06 24.5 0.0 1.8e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KXH36581.1 - 0.00019 20.7 0.1 0.00035 19.8 0.1 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II EutN_CcmL PF03319.13 KXH36581.1 - 0.018 15.6 0.2 0.038 14.6 0.2 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutN/carboxysome DegT_DnrJ_EryC1 PF01041.17 KXH36581.1 - 0.033 13.5 0.4 0.059 12.7 0.4 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family MFS_1 PF07690.16 KXH36582.1 - 7.9e-05 21.7 23.1 0.00011 21.2 21.0 2.1 2 0 0 2 2 2 1 Major Facilitator Superfamily QueT PF06177.11 KXH36582.1 - 0.0045 17.4 9.9 0.0045 17.4 9.9 2.3 2 1 1 3 3 3 1 QueT transporter AMP-binding PF00501.28 KXH36583.1 - 1.1e-292 969.7 0.0 3.6e-79 266.3 0.0 4.2 4 0 0 4 4 4 4 AMP-binding enzyme Condensation PF00668.20 KXH36583.1 - 2.2e-159 531.0 0.0 1.3e-46 159.3 0.0 4.4 4 0 0 4 4 4 4 Condensation domain PP-binding PF00550.25 KXH36583.1 - 7.7e-51 170.3 0.0 1.2e-12 48.0 0.0 5.2 4 0 0 4 4 4 4 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KXH36583.1 - 6.2e-13 49.5 2.2 0.051 14.6 0.1 5.4 5 0 0 5 5 5 4 AMP-binding enzyme C-terminal domain Fungal_trans_2 PF11951.8 KXH36584.1 - 2.8e-13 49.5 1.3 9.7e-13 47.7 1.3 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain PEP_mutase PF13714.6 KXH36585.1 - 4.9e-46 157.1 0.8 7.1e-46 156.6 0.8 1.3 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 KXH36585.1 - 1.9e-13 49.8 0.1 2.6e-13 49.3 0.1 1.1 1 0 0 1 1 1 1 Isocitrate lyase family Pantoate_transf PF02548.15 KXH36585.1 - 0.009 15.4 0.0 0.038 13.4 0.0 1.9 2 0 0 2 2 2 1 Ketopantoate hydroxymethyltransferase DAHP_synth_1 PF00793.20 KXH36585.1 - 0.055 12.3 0.0 2.1 7.2 0.0 2.5 3 0 0 3 3 3 0 DAHP synthetase I family Zn_clus PF00172.18 KXH36586.1 - 1.3e-06 28.4 11.7 2.6e-06 27.4 11.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 KXH36587.1 - 1.3e-22 80.2 19.1 1.3e-22 80.2 19.1 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily TFIID_30kDa PF03540.13 KXH36588.1 - 1.4e-25 89.0 0.3 2.2e-25 88.3 0.3 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit Mucin PF01456.17 KXH36588.1 - 0.55 10.2 8.1 0.85 9.6 8.1 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Ribosomal_S19 PF00203.21 KXH36589.1 - 5.5e-27 93.5 0.0 8.9e-27 92.8 0.0 1.4 2 0 0 2 2 2 1 Ribosomal protein S19 Cellulase PF00150.18 KXH36590.1 - 1.5e-48 165.6 1.9 2e-48 165.3 1.9 1.0 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF4038 PF13204.6 KXH36590.1 - 0.00058 19.6 0.1 0.00086 19.0 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4038) Pho88 PF10032.9 KXH36591.1 - 5.8e-81 270.1 0.1 6.7e-81 269.9 0.1 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) AnkUBD PF18418.1 KXH36591.1 - 0.08 13.1 0.0 0.17 12.1 0.0 1.6 1 1 0 1 1 1 0 Ankyrin ubiquitin-binding domain XPA_C PF05181.12 KXH36592.1 - 7.4e-26 89.9 2.3 2e-25 88.5 2.3 1.8 1 0 0 1 1 1 1 XPA protein C-terminus XPA_N PF01286.18 KXH36592.1 - 0.00084 19.3 2.8 0.00084 19.3 2.8 1.9 2 0 0 2 2 2 1 XPA protein N-terminal MAS20 PF02064.15 KXH36592.1 - 0.093 12.8 2.0 0.19 11.8 2.0 1.5 1 0 0 1 1 1 0 MAS20 protein import receptor Endonuc_Holl PF10107.9 KXH36592.1 - 0.1 12.5 1.7 0.17 11.7 1.7 1.3 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase ArfGap PF01412.18 KXH36592.1 - 0.92 9.6 3.4 0.45 10.6 0.4 1.9 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf Striatin PF08232.12 KXH36593.1 - 1.6e-42 145.7 2.6 1.6e-42 145.7 2.6 2.5 2 0 0 2 2 2 1 Striatin family WD40 PF00400.32 KXH36593.1 - 1.8e-27 95.0 19.7 2.9e-05 24.7 0.0 8.0 7 1 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXH36593.1 - 3e-06 27.4 0.0 5.1 7.5 0.0 5.0 3 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain TFIIA PF03153.13 KXH36593.1 - 0.0016 18.5 11.7 0.0016 18.5 11.7 2.1 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit ADH_N_2 PF16884.5 KXH36593.1 - 0.071 13.0 0.3 0.19 11.7 0.0 1.8 2 0 0 2 2 2 0 N-terminal domain of oxidoreductase MNSV_P7B PF06692.11 KXH36593.1 - 0.088 12.8 0.0 0.45 10.5 0.0 2.2 1 0 0 1 1 1 0 Melon necrotic spot virus P7B protein Cytochrom_D1 PF02239.16 KXH36593.1 - 0.13 10.8 0.0 0.3 9.6 0.0 1.5 2 0 0 2 2 2 0 Cytochrome D1 heme domain Ge1_WD40 PF16529.5 KXH36593.1 - 0.15 11.0 0.0 0.84 8.5 0.0 2.2 2 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Spt20 PF12090.8 KXH36593.1 - 1.2 8.7 13.7 2 7.9 13.7 1.3 1 0 0 1 1 1 0 Spt20 family Phostensin PF13914.6 KXH36593.1 - 7.3 7.2 8.3 21 5.7 8.3 1.7 1 0 0 1 1 1 0 Phostensin PP1-binding and SH3-binding region BC10 PF06726.12 KXH36595.1 - 8.4e-18 64.4 11.4 1.5e-17 63.6 11.4 1.4 1 0 0 1 1 1 1 Bladder cancer-related protein BC10 LicD PF04991.13 KXH36596.1 - 5.3e-24 85.6 7.6 1.2e-16 61.6 3.5 2.1 1 1 1 2 2 2 2 LicD family WLM PF08325.10 KXH36597.1 - 2e-50 171.5 0.0 2e-50 171.5 0.0 1.4 2 0 0 2 2 2 1 WLM domain DUF45 PF01863.17 KXH36597.1 - 0.00013 22.1 0.8 0.00027 21.1 0.8 1.4 1 0 0 1 1 1 1 Protein of unknown function DUF45 Reprolysin_5 PF13688.6 KXH36597.1 - 0.034 14.3 0.4 0.066 13.4 0.3 1.5 1 1 0 1 1 1 0 Metallo-peptidase family M12 SprT-like PF10263.9 KXH36597.1 - 0.04 13.8 0.1 0.084 12.7 0.1 1.7 1 0 0 1 1 1 0 SprT-like family ER_lumen_recept PF00810.18 KXH36598.1 - 4.6e-54 183.3 9.2 4.6e-54 183.3 9.2 1.4 2 0 0 2 2 2 1 ER lumen protein retaining receptor PQ-loop PF04193.14 KXH36598.1 - 1.3 8.9 14.1 0.38 10.6 1.0 3.2 4 0 0 4 4 4 0 PQ loop repeat DUF2207 PF09972.9 KXH36599.1 - 0.033 13.0 0.0 0.057 12.2 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) ISG65-75 PF11727.8 KXH36599.1 - 0.11 11.8 22.0 0.029 13.6 4.3 2.3 1 1 1 2 2 2 0 Invariant surface glycoprotein Macoilin PF09726.9 KXH36599.1 - 0.28 9.7 10.1 0.37 9.3 10.1 1.1 1 0 0 1 1 1 0 Macoilin family RNase_H2_suC PF08615.11 KXH36599.1 - 0.33 11.1 4.0 0.5 10.5 2.9 2.0 2 1 0 2 2 2 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) FAM196 PF15265.6 KXH36599.1 - 1.3 8.4 16.7 2.1 7.8 16.7 1.3 1 0 0 1 1 1 0 FAM196 family DUF3584 PF12128.8 KXH36599.1 - 1.5 6.3 27.3 2.2 5.7 27.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) RIFIN PF02009.16 KXH36599.1 - 2.2 8.1 20.6 5.2 6.9 20.6 1.5 1 1 0 1 1 1 0 Rifin LapA_dom PF06305.11 KXH36599.1 - 2.4 8.0 4.8 0.94 9.3 0.1 2.7 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain DUF966 PF06136.13 KXH36599.1 - 3.6 7.2 10.7 5.2 6.7 10.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF966) DUF2232 PF09991.9 KXH36599.1 - 5.5 6.1 6.4 8.9 5.4 0.1 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2232) MSC PF09402.10 KXH36599.1 - 6.9 6.0 6.9 10 5.4 6.9 1.2 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain Ank_4 PF13637.6 KXH36601.1 - 1.8e-12 47.5 1.4 7.9e-07 29.5 0.0 4.4 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXH36601.1 - 1.3e-11 44.9 3.1 2.9e-06 27.8 0.5 3.6 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXH36601.1 - 1.2e-10 41.5 1.9 1.2e-06 28.7 0.2 4.0 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 KXH36601.1 - 1.9e-10 40.7 1.6 0.0042 17.5 0.0 4.5 5 0 0 5 5 5 2 Ankyrin repeat Ank_3 PF13606.6 KXH36601.1 - 8.8e-07 28.8 1.6 0.082 13.5 0.0 5.1 4 1 0 4 4 4 2 Ankyrin repeat Pec_lyase_C PF00544.19 KXH36602.1 - 1.5e-15 57.4 9.5 1.2e-13 51.2 9.5 2.3 1 1 0 1 1 1 1 Pectate lyase MFS_1 PF07690.16 KXH36603.1 - 5.4e-19 68.3 2.7 5.4e-19 68.3 2.7 2.1 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF2070 PF09843.9 KXH36603.1 - 0.00035 19.0 2.2 0.00055 18.4 2.2 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2070) Sensor PF13796.6 KXH36603.1 - 0.00044 20.3 6.2 0.025 14.6 6.2 2.7 1 1 0 1 1 1 1 Putative sensor Lyase_1 PF00206.20 KXH36604.1 - 4.5e-46 157.7 0.0 8.3e-46 156.8 0.0 1.4 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 KXH36604.1 - 7.4e-20 71.3 0.1 2.3e-19 69.7 0.1 1.9 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus Fungal_trans_2 PF11951.8 KXH36605.1 - 1.6e-07 30.5 0.0 3.7e-06 26.0 0.0 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Fungal_trans PF04082.18 KXH36606.1 - 5e-24 84.8 0.0 7e-24 84.3 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Aldo_ket_red PF00248.21 KXH36607.1 - 3e-49 167.8 0.0 6e-47 160.2 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Death PF00531.22 KXH36607.1 - 0.0069 16.5 0.0 1.2 9.4 0.0 3.1 2 1 1 3 3 3 1 Death domain APH PF01636.23 KXH36748.1 - 7.4e-10 39.2 3.1 2.3e-08 34.2 3.1 2.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KXH36748.1 - 2.2e-09 37.0 0.0 3.6e-07 29.8 0.0 2.1 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KXH36748.1 - 4.2e-07 29.6 0.0 8.1e-07 28.7 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_fungal PF17667.1 KXH36748.1 - 0.0076 15.1 0.0 0.011 14.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_Tyr PF07714.17 KXH36748.1 - 0.015 14.6 0.0 0.018 14.3 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase RIO1 PF01163.22 KXH36748.1 - 0.075 12.6 0.0 1.6 8.3 0.0 2.4 2 0 0 2 2 2 0 RIO1 family Choline_kinase PF01633.20 KXH36748.1 - 0.2 11.2 0.0 0.27 10.8 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Acyl_transf_3 PF01757.22 KXH36749.1 - 6.2e-45 153.7 34.4 7.8e-45 153.4 34.4 1.1 1 0 0 1 1 1 1 Acyltransferase family ALAD PF00490.21 KXH36750.1 - 3.5e-120 400.9 0.0 4.2e-120 400.7 0.0 1.1 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase DNA_pol_viral_N PF00242.17 KXH36752.1 - 0.38 10.2 7.5 0.1 12.1 3.0 1.8 1 1 1 2 2 2 0 DNA polymerase (viral) N-terminal domain Mucin PF01456.17 KXH36752.1 - 0.99 9.4 6.4 1.6 8.7 6.4 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Y_phosphatase3 PF13350.6 KXH36753.1 - 6.6e-47 160.4 0.0 7.8e-47 160.2 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 KXH36753.1 - 0.031 14.4 0.0 0.36 10.9 0.0 2.1 2 0 0 2 2 2 0 Inositol hexakisphosphate Y_phosphatase PF00102.27 KXH36753.1 - 0.16 11.6 0.0 0.2 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.13 KXH36753.1 - 0.23 11.0 0.0 0.36 10.4 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family Amidohydro_3 PF07969.11 KXH36754.1 - 8.1e-67 226.7 0.0 1e-66 226.3 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 KXH36754.1 - 8.6e-06 25.3 0.0 0.00046 19.6 0.0 2.3 2 1 0 2 2 2 2 Amidohydrolase family MFS_1 PF07690.16 KXH36755.1 - 3.1e-11 42.8 24.9 3.1e-11 42.8 24.9 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily PUCC PF03209.15 KXH36755.1 - 0.00078 18.6 0.3 0.00078 18.6 0.3 3.1 3 1 1 4 4 4 1 PUCC protein Methyltransf_23 PF13489.6 KXH36756.1 - 3.7e-21 75.7 0.0 5.4e-21 75.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH36756.1 - 4.5e-11 43.3 0.0 1.9e-10 41.3 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH36756.1 - 4.3e-09 36.9 0.0 8.1e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH36756.1 - 3.1e-07 31.1 0.0 3.3e-06 27.7 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH36756.1 - 9.1e-07 28.8 0.0 1.8e-05 24.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXH36756.1 - 0.023 14.2 0.0 0.047 13.2 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase small domain Ubie_methyltran PF01209.18 KXH36756.1 - 0.029 13.7 0.0 0.27 10.6 0.0 2.2 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family PrmA PF06325.13 KXH36756.1 - 0.091 12.1 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Opy2 PF09463.10 KXH36757.1 - 2.1e-08 34.3 18.1 3.3e-08 33.7 18.1 1.3 1 0 0 1 1 1 1 Opy2 protein PTP_tm PF18861.1 KXH36757.1 - 0.02 14.9 0.1 0.22 11.5 0.2 2.2 2 0 0 2 2 2 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J Mid2 PF04478.12 KXH36757.1 - 0.061 13.2 0.1 0.11 12.3 0.1 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Chitin_synth_1 PF01644.17 KXH36759.1 - 4e-68 228.5 0.0 5.6e-68 228.0 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 KXH36759.1 - 1e-27 95.8 0.0 2.3e-27 94.7 0.0 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 KXH36759.1 - 1.4e-26 93.2 0.1 1.4e-21 76.7 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 KXH36759.1 - 4.9e-08 33.1 2.3 4.9e-08 33.1 2.3 2.3 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KXH36759.1 - 0.017 15.1 0.0 0.042 13.7 0.0 1.7 2 0 0 2 2 2 0 Glycosyltransferase like family 2 UQ_con PF00179.26 KXH36760.1 - 1.2e-36 125.5 0.0 1.8e-36 124.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme IlvN PF07991.12 KXH36761.1 - 4.5e-46 156.4 0.0 8.5e-46 155.5 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 KXH36761.1 - 2.4e-41 141.4 0.0 3.6e-41 140.8 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.17 KXH36761.1 - 0.015 15.9 0.1 0.061 13.9 0.0 2.1 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Fungal_TACC PF12709.7 KXH36762.1 - 1.5e-10 41.3 2.4 1.5e-10 41.3 2.4 3.9 3 1 1 4 4 4 2 Fungal Transforming acidic coiled-coil (TACC) proteins LPP PF04728.13 KXH36762.1 - 0.31 11.5 5.1 1.6 9.1 0.3 3.6 3 0 0 3 3 3 0 Lipoprotein leucine-zipper DUF1848 PF08902.11 KXH36762.1 - 0.68 9.6 5.2 0.081 12.6 0.7 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1848) FliE PF02049.18 KXH36762.1 - 0.69 10.1 7.7 3.6 7.8 2.1 3.0 2 0 0 2 2 2 0 Flagellar hook-basal body complex protein FliE GIT_CC PF16559.5 KXH36762.1 - 0.84 9.6 5.3 3.9 7.4 0.0 3.3 4 0 0 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF4482 PF14818.6 KXH36762.1 - 7.9 7.3 24.6 0.23 12.3 2.5 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4482) NmrA PF05368.13 KXH36801.1 - 1.1e-79 267.3 0.0 1.4e-79 266.9 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXH36801.1 - 2.5e-07 30.8 0.6 8.9e-06 25.7 0.2 2.5 2 1 0 2 2 2 1 NAD(P)H-binding DUF755 PF05501.11 KXH36801.1 - 0.32 11.3 5.7 0.51 10.6 5.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Methyltransf_23 PF13489.6 KXH36841.1 - 1.3e-20 73.9 0.0 1.9e-20 73.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH36841.1 - 7.6e-12 45.8 0.0 1.8e-11 44.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH36841.1 - 5.4e-11 43.1 0.0 2.4e-10 41.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH36841.1 - 2e-10 40.7 0.0 1.3e-09 38.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH36841.1 - 3.1e-09 37.4 0.0 6.3e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 KXH36841.1 - 0.00091 19.4 0.0 0.0013 18.9 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.14 KXH36841.1 - 0.0026 17.3 0.0 0.03 13.9 0.0 2.5 3 0 0 3 3 3 1 Methyltransferase small domain CheR PF01739.18 KXH36841.1 - 0.018 14.5 0.0 0.058 12.9 0.0 1.8 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain Ubie_methyltran PF01209.18 KXH36841.1 - 0.068 12.5 0.0 0.49 9.7 0.0 2.1 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_17 PF12692.7 KXH36841.1 - 0.084 12.9 0.0 2.1 8.3 0.0 2.7 3 0 0 3 3 3 0 S-adenosyl-L-methionine methyltransferase Methyltransf_2 PF00891.18 KXH36841.1 - 0.11 11.8 0.0 0.26 10.6 0.0 1.7 1 1 0 1 1 1 0 O-methyltransferase domain RTA1 PF04479.13 KXH36842.1 - 4.4e-34 117.9 3.8 6e-29 101.1 0.4 2.7 3 0 0 3 3 3 2 RTA1 like protein DUF983 PF06170.12 KXH36842.1 - 5 7.6 6.0 5.8 7.4 0.4 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF983) Abhydrolase_6 PF12697.7 KXH36843.1 - 2.1e-16 61.2 0.2 2.8e-16 60.8 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXH36843.1 - 0.0023 17.3 0.1 0.0038 16.5 0.1 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KXH36843.1 - 0.0066 16.1 0.1 3.2 7.3 0.0 2.5 3 0 0 3 3 3 2 alpha/beta hydrolase fold Ser_hydrolase PF06821.13 KXH36843.1 - 0.028 14.3 0.0 0.45 10.3 0.0 2.1 2 0 0 2 2 2 0 Serine hydrolase Thioesterase PF00975.20 KXH36843.1 - 0.043 13.9 0.0 0.088 12.9 0.0 1.5 1 0 0 1 1 1 0 Thioesterase domain DUF900 PF05990.12 KXH36843.1 - 0.18 11.3 0.0 0.27 10.7 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) TBCA PF02970.16 KXH36844.1 - 2.8e-21 75.6 4.1 2.8e-21 75.6 4.1 1.4 1 1 0 1 1 1 1 Tubulin binding cofactor A Cytochrom_C552 PF02335.15 KXH36844.1 - 0.054 12.4 0.2 0.07 12.0 0.2 1.1 1 0 0 1 1 1 0 Cytochrome c552 Spc7 PF08317.11 KXH36844.1 - 0.22 10.3 5.2 0.14 11.0 2.7 1.7 1 1 0 1 1 1 0 Spc7 kinetochore protein Csm1_N PF18504.1 KXH36844.1 - 1.4 9.3 6.5 1.1 9.6 1.1 2.7 1 1 2 3 3 3 0 Csm1 N-terminal domain THOC7 PF05615.13 KXH36845.1 - 1.3e-42 145.2 6.5 1.3e-42 145.2 6.5 2.1 1 1 1 2 2 2 1 Tho complex subunit 7 FUSC PF04632.12 KXH36845.1 - 0.23 10.0 5.3 0.31 9.5 5.3 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Herpes_UL17 PF04559.12 KXH36845.1 - 0.37 9.5 7.5 0.19 10.5 4.4 1.8 1 1 1 2 2 2 0 Herpesvirus UL17 protein YabA PF06156.13 KXH36845.1 - 1.7 9.3 11.2 3.1 8.5 0.7 2.8 2 1 1 3 3 3 0 Initiation control protein YabA EzrA PF06160.12 KXH36845.1 - 2.2 6.3 14.3 2 6.5 4.6 2.2 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA APG6_N PF17675.1 KXH36845.1 - 2.8 8.5 22.1 16 6.0 7.0 2.8 1 1 1 2 2 2 0 Apg6 coiled-coil region Golgin_A5 PF09787.9 KXH36845.1 - 5.6 6.3 19.5 1.1 8.6 8.4 2.2 1 1 1 2 2 2 0 Golgin subfamily A member 5 Sec66 PF09802.9 KXH36845.1 - 8.1 6.0 9.9 1.1 8.8 1.8 2.1 2 0 0 2 2 2 0 Preprotein translocase subunit Sec66 zf-CCCH_4 PF18044.1 KXH36846.1 - 0.00088 19.0 1.4 0.026 14.3 0.1 4.7 6 0 0 6 6 6 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KXH36846.1 - 0.0018 18.2 28.1 0.69 10.1 0.5 6.0 5 1 0 5 5 5 4 Zinc finger domain zf-CCCH PF00642.24 KXH36846.1 - 0.0029 17.5 22.3 2.2 8.3 3.6 5.4 4 1 1 5 5 5 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 KXH36846.1 - 0.007 16.6 13.2 0.044 14.0 0.9 3.3 1 1 2 3 3 3 2 Zinc-finger containing family Torus PF16131.5 KXH36846.1 - 3.7 8.3 22.5 1.9 9.2 0.4 4.5 2 1 2 4 4 4 0 Torus domain Sel1 PF08238.12 KXH36847.1 - 0.00082 20.0 1.0 0.096 13.4 0.0 3.1 3 1 0 3 3 3 1 Sel1 repeat TraC PF07820.12 KXH36847.1 - 0.6 10.5 3.9 1.1 9.7 0.1 2.9 2 0 0 2 2 2 0 TraC-like protein bZIP_1 PF00170.21 KXH36848.1 - 1.4e-09 37.9 15.8 1.4e-09 37.9 15.8 2.4 2 0 0 2 2 2 1 bZIP transcription factor bZIP_Maf PF03131.17 KXH36848.1 - 4.3e-08 33.6 13.4 1.2e-07 32.1 13.4 1.7 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_2 PF07716.15 KXH36848.1 - 0.00053 20.0 14.9 0.00053 20.0 14.9 2.6 2 1 1 3 3 3 1 Basic region leucine zipper UPF0242 PF06785.11 KXH36848.1 - 0.041 14.0 20.2 0.076 13.1 20.2 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Sec5 PF15469.6 KXH36848.1 - 0.046 13.5 6.0 0.091 12.6 6.0 1.4 1 0 0 1 1 1 0 Exocyst complex component Sec5 DUF2205 PF10224.9 KXH36848.1 - 0.095 12.7 10.0 0.1 12.6 8.4 1.9 1 1 0 1 1 1 0 Short coiled-coil protein CENP-F_leu_zip PF10473.9 KXH36848.1 - 0.37 10.8 20.9 5.8 6.9 21.3 2.4 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fmp27_WPPW PF10359.9 KXH36848.1 - 0.77 8.5 12.3 1.2 7.9 12.3 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF4441 PF14536.6 KXH36848.1 - 0.84 9.8 4.0 2.2 8.5 3.9 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4441) DUF874 PF05917.11 KXH36848.1 - 2.4 7.1 10.5 3.6 6.5 10.5 1.1 1 0 0 1 1 1 0 Helicobacter pylori protein of unknown function (DUF874) FapA PF03961.13 KXH36848.1 - 2.7 6.5 10.2 4 5.9 10.2 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF5320 PF17253.2 KXH36848.1 - 3.3 8.8 6.4 5.3 8.2 0.2 2.9 1 1 1 2 2 2 0 Family of unknown function (DUF5320) 5_nucleotid PF05761.14 KXH36848.1 - 4.3 6.1 9.0 6.7 5.5 9.0 1.2 1 0 0 1 1 1 0 5' nucleotidase family GBP_C PF02841.14 KXH36848.1 - 4.5 6.6 17.6 9.3 5.6 17.6 1.4 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Transp_cyt_pur PF02133.15 KXH36905.1 - 1.4e-18 66.9 34.3 2.2e-18 66.3 34.3 1.2 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin TrbC PF04956.13 KXH36905.1 - 7.6 6.8 16.0 9.7 6.5 0.1 3.8 3 0 0 3 3 3 0 TrbC/VIRB2 family Oxysterol_BP PF01237.18 KXH36916.1 - 7.8e-135 449.5 0.0 7.8e-135 449.5 0.0 2.7 3 0 0 3 3 3 1 Oxysterol-binding protein Ank PF00023.30 KXH36916.1 - 1.2e-14 54.0 0.4 6.3e-05 23.2 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 KXH36916.1 - 5e-14 52.2 0.1 8.1e-07 29.2 0.0 3.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXH36916.1 - 5.4e-14 52.5 0.1 1.4e-09 38.4 0.0 2.7 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXH36916.1 - 8.7e-12 45.3 0.0 8.7e-07 29.4 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXH36916.1 - 2.6e-11 42.7 0.0 0.0015 18.9 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat PH PF00169.29 KXH36916.1 - 2.6e-11 44.0 0.8 5.8e-11 42.8 0.8 1.7 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 KXH36916.1 - 1.4e-07 31.7 1.0 3.9e-07 30.3 1.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 KXH36916.1 - 2.5e-05 24.6 2.3 7e-05 23.2 2.3 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain Hypoth_Ymh PF09509.10 KXH36916.1 - 0.19 11.6 2.2 2.3 8.2 0.5 3.0 4 0 0 4 4 4 0 Protein of unknown function (Hypoth_ymh) 4HBT_3 PF13622.6 KXH36917.1 - 5.2e-81 272.5 0.4 6.2e-81 272.3 0.4 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 KXH36917.1 - 3.3e-25 88.5 0.0 2.4e-10 40.4 0.0 4.1 3 1 0 3 3 3 3 Acyl-CoA thioesterase Ge1_WD40 PF16529.5 KXH36917.1 - 0.15 10.9 0.0 0.2 10.6 0.0 1.1 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein ABM PF03992.16 KXH36918.1 - 0.013 15.5 0.3 1.2 9.3 0.4 2.3 2 0 0 2 2 2 0 Antibiotic biosynthesis monooxygenase FAD_binding_4 PF01565.23 KXH36919.1 - 3.2e-21 75.5 0.0 7.6e-21 74.3 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.19 KXH36919.1 - 4.5e-08 33.0 0.0 6.6e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain ketoacyl-synt PF00109.26 KXH36922.1 - 1.9e-75 253.7 0.0 5e-74 249.1 0.0 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KXH36922.1 - 7.5e-35 119.5 0.1 1.9e-34 118.2 0.0 1.8 2 0 0 2 2 1 1 Beta-ketoacyl synthase, C-terminal domain HTH_51 PF18558.1 KXH36922.1 - 1.2e-25 89.2 0.0 7.8e-25 86.6 0.0 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain PP-binding PF00550.25 KXH36922.1 - 3.4e-22 78.6 5.9 1.3e-14 54.3 1.0 2.6 2 0 0 2 2 2 2 Phosphopantetheine attachment site PS-DH PF14765.6 KXH36922.1 - 3.2e-21 75.9 0.4 8e-21 74.5 0.1 1.8 2 0 0 2 2 2 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 KXH36922.1 - 9.1e-19 68.1 0.1 2.8e-18 66.5 0.0 1.8 2 0 0 2 2 2 1 Acyl transferase domain Methyltransf_12 PF08242.12 KXH36922.1 - 2.6e-14 53.8 0.0 6.4e-14 52.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Abhydrolase_3 PF07859.13 KXH36922.1 - 1.7e-12 47.6 0.0 1e-10 41.9 0.0 2.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Methyltransf_23 PF13489.6 KXH36922.1 - 2.9e-10 40.2 0.0 8.6e-10 38.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH36922.1 - 2.3e-09 37.8 0.0 7.4e-09 36.2 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH36922.1 - 3.3e-07 30.8 0.0 9.5e-07 29.4 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH36922.1 - 3.4e-07 30.2 0.0 7.6e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 KXH36922.1 - 1.9e-05 25.1 0.0 5e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Peptidase_S9 PF00326.21 KXH36922.1 - 2.9e-05 23.6 0.0 0.096 12.1 0.0 2.9 3 0 0 3 3 3 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 KXH36922.1 - 4.2e-05 24.3 4.2 4.2e-05 24.3 4.2 3.6 3 1 0 3 3 3 1 Alpha/beta hydrolase family PP-binding_2 PF14573.6 KXH36922.1 - 0.00018 21.7 1.1 0.89 9.8 0.1 2.8 3 0 0 3 3 2 2 Acyl-carrier Thiolase_N PF00108.23 KXH36922.1 - 0.00027 20.4 0.1 0.0043 16.5 0.1 2.3 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thioesterase PF00975.20 KXH36922.1 - 0.016 15.3 0.0 0.69 10.0 0.0 2.5 2 0 0 2 2 2 0 Thioesterase domain Methyltransf_33 PF10017.9 KXH36922.1 - 0.056 12.6 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent DLH PF01738.18 KXH36922.1 - 0.057 13.0 0.0 3.1 7.3 0.0 2.4 2 0 0 2 2 2 0 Dienelactone hydrolase family Methyltransf_16 PF10294.9 KXH36922.1 - 0.097 12.4 0.0 0.5 10.1 0.0 2.1 2 1 0 2 2 2 0 Lysine methyltransferase p450 PF00067.22 KXH36923.1 - 1.8e-50 172.1 0.0 2.3e-50 171.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Trp_DMAT PF11991.8 KXH36924.1 - 2.6e-93 313.3 0.0 1.8e-92 310.6 0.0 1.8 2 0 0 2 2 2 1 Tryptophan dimethylallyltransferase Fungal_trans_2 PF11951.8 KXH36925.1 - 1.2e-05 24.3 0.7 2.5e-05 23.3 0.2 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain FAD_binding_4 PF01565.23 KXH36926.1 - 4.4e-20 71.8 0.3 7.6e-20 71.1 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KXH36926.1 - 0.00044 20.3 0.3 0.0011 19.1 0.3 1.7 1 0 0 1 1 1 1 Berberine and berberine like adh_short PF00106.25 KXH36927.1 - 7e-17 61.5 0.0 9.9e-17 61.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXH36927.1 - 2.3e-13 50.2 0.0 3.5e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH36927.1 - 9.3e-06 25.7 0.1 1.5e-05 25.0 0.1 1.3 1 0 0 1 1 1 1 KR domain ThiF PF00899.21 KXH36927.1 - 0.013 14.9 0.1 0.018 14.4 0.1 1.2 1 0 0 1 1 1 0 ThiF family Ldh_1_N PF00056.23 KXH36927.1 - 0.017 15.3 0.3 0.03 14.4 0.3 1.5 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Epimerase PF01370.21 KXH36927.1 - 0.039 13.4 0.0 0.085 12.3 0.1 1.5 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KXH36927.1 - 0.099 11.7 0.1 0.4 9.7 0.1 1.8 2 0 0 2 2 2 0 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KXH36927.1 - 0.23 10.6 0.0 0.32 10.1 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein adh_short PF00106.25 KXH36928.1 - 1.6e-19 70.2 1.8 4e-17 62.3 0.7 2.2 1 1 1 2 2 2 2 short chain dehydrogenase KR PF08659.10 KXH36928.1 - 1.4e-15 57.6 0.1 2.1e-15 57.1 0.1 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 KXH36928.1 - 4.5e-12 46.0 1.9 8.6e-10 38.6 0.2 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase NAD_binding_4 PF07993.12 KXH36928.1 - 0.009 15.2 0.1 0.13 11.4 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein ATP-grasp_5 PF13549.6 KXH36928.1 - 0.015 14.8 0.0 0.03 13.8 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain Epimerase PF01370.21 KXH36928.1 - 0.077 12.4 0.3 0.61 9.5 0.3 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family AMP-binding PF00501.28 KXH36930.1 - 2.3e-31 108.8 0.0 4.3e-31 107.9 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 KXH36930.1 - 5.2e-28 97.9 0.0 8.3e-28 97.2 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 KXH36930.1 - 6e-11 42.3 0.0 1.3e-10 41.1 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KXH36930.1 - 0.00032 21.0 0.1 0.0012 19.1 0.1 2.1 1 1 0 1 1 1 1 Phosphopantetheine attachment site KR PF08659.10 KXH36930.1 - 0.0041 17.1 0.1 0.014 15.3 0.0 2.0 2 0 0 2 2 2 1 KR domain GDP_Man_Dehyd PF16363.5 KXH36930.1 - 0.012 15.0 0.0 0.022 14.1 0.0 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KXH36930.1 - 0.015 14.4 0.0 0.13 11.4 0.0 2.0 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KXH36930.1 - 0.017 14.2 0.0 0.13 11.4 0.0 2.0 2 0 0 2 2 2 0 RmlD substrate binding domain FB_lectin PF07367.11 KXH36930.1 - 0.19 11.7 0.0 28 4.6 0.0 2.3 2 0 0 2 2 2 0 Fungal fruit body lectin ApbA PF02558.16 KXH36933.1 - 6.1e-24 84.4 0.0 9.9e-24 83.7 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 KXH36933.1 - 2.2e-21 76.4 0.0 3.3e-21 75.8 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal DASH_Hsk3 PF08227.11 KXH36934.1 - 1.8e-20 73.0 2.4 2.8e-20 72.4 2.4 1.3 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like SMYLE_N PF18615.1 KXH36934.1 - 0.029 13.9 0.2 0.035 13.7 0.2 1.1 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain Amino_oxidase PF01593.24 KXH36935.1 - 3.4e-25 89.2 0.6 7.5e-24 84.8 0.6 2.4 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KXH36935.1 - 1.3e-14 54.1 0.1 3.7e-14 52.7 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXH36935.1 - 8.3e-13 48.6 1.2 1.8e-11 44.2 1.2 2.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXH36935.1 - 4.4e-09 36.0 0.1 1.6e-05 24.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXH36935.1 - 7.7e-08 31.8 3.2 9.5e-05 21.6 2.8 2.2 2 0 0 2 2 2 2 FAD binding domain HI0933_like PF03486.14 KXH36935.1 - 1.1e-07 30.9 0.2 0.0015 17.3 0.9 2.1 2 0 0 2 2 2 2 HI0933-like protein FAD_oxidored PF12831.7 KXH36935.1 - 4e-05 23.1 0.0 0.0015 17.9 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KXH36935.1 - 0.00021 20.6 0.7 0.00043 19.6 0.7 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KXH36935.1 - 0.0015 17.8 0.4 0.0026 17.1 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 KXH36935.1 - 0.0017 18.9 2.7 0.36 11.4 1.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXH36935.1 - 0.0094 15.2 0.1 0.016 14.4 0.1 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 KXH36935.1 - 0.014 15.3 3.5 0.052 13.5 0.2 2.5 3 0 0 3 3 2 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KXH36935.1 - 0.018 14.1 0.4 0.018 14.1 0.4 2.0 3 0 0 3 3 3 0 Lycopene cyclase protein GMC_oxred_N PF00732.19 KXH36935.1 - 0.02 14.3 0.1 1.9 7.8 0.0 2.2 2 0 0 2 2 2 0 GMC oxidoreductase Trp_halogenase PF04820.14 KXH36935.1 - 0.048 12.5 0.4 7.9 5.2 0.0 2.5 2 0 0 2 2 2 0 Tryptophan halogenase ApbA PF02558.16 KXH36935.1 - 0.048 13.3 1.0 0.099 12.3 1.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA XdhC_C PF13478.6 KXH36935.1 - 0.079 13.5 0.0 0.69 10.4 0.0 2.3 2 0 0 2 2 2 0 XdhC Rossmann domain GIDA PF01134.22 KXH36935.1 - 0.092 11.8 2.5 0.23 10.5 1.4 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A GDI PF00996.18 KXH36935.1 - 0.13 10.8 0.0 1.3 7.4 0.0 2.3 3 0 0 3 3 3 0 GDP dissociation inhibitor adh_short PF00106.25 KXH36935.1 - 0.27 10.7 0.6 0.45 9.9 0.6 1.3 1 0 0 1 1 1 0 short chain dehydrogenase SQS_PSY PF00494.19 KXH36936.1 - 2.9e-64 217.1 0.2 3.8e-64 216.7 0.2 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase p450 PF00067.22 KXH37192.1 - 2.6e-74 250.6 0.0 3.7e-74 250.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Phe_tRNA-synt_N PF02912.18 KXH37192.1 - 0.063 13.2 0.3 0.11 12.4 0.3 1.4 1 0 0 1 1 1 0 Aminoacyl tRNA synthetase class II, N-terminal domain Abhydrolase_6 PF12697.7 KXH37193.1 - 6.6e-22 79.2 1.1 6.6e-22 79.2 1.1 1.4 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXH37193.1 - 7.2e-07 28.7 0.0 1.2e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KXH37193.1 - 4.6e-06 26.5 0.9 0.067 12.8 0.5 3.2 2 1 0 2 2 2 2 alpha/beta hydrolase fold Thioesterase PF00975.20 KXH37193.1 - 0.011 15.9 0.0 0.033 14.3 0.0 1.8 1 1 0 1 1 1 0 Thioesterase domain PGAP1 PF07819.13 KXH37193.1 - 0.11 12.2 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein TRP PF06011.12 KXH37194.1 - 4.6e-145 483.6 13.2 5.7e-145 483.3 13.2 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 KXH37194.1 - 2.6e-40 138.0 4.8 4.7e-40 137.2 4.8 1.4 1 0 0 1 1 1 1 ML-like domain Shisa PF13908.6 KXH37194.1 - 0.94 9.7 3.2 23 5.2 1.0 2.5 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator Pex16 PF08610.10 KXH37195.1 - 4.6e-137 456.5 2.2 5.5e-125 416.8 0.3 2.0 1 1 1 2 2 2 2 Peroxisomal membrane protein (Pex16) Fungal_trans PF04082.18 KXH37196.1 - 7.6e-23 80.9 0.2 1.3e-22 80.1 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH37196.1 - 6.3e-08 32.6 10.6 1.2e-07 31.7 10.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Brr6_like_C_C PF10104.9 KXH37197.1 - 5e-36 123.4 5.1 6.4e-36 123.1 5.1 1.1 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain PBP1_TM PF14812.6 KXH37197.1 - 0.0086 16.4 5.1 0.047 14.1 2.5 2.9 3 0 0 3 3 3 1 Transmembrane domain of transglycosylase PBP1 at N-terminal Med26 PF08711.11 KXH37198.1 - 1.4e-11 44.2 0.0 3.2e-11 43.1 0.0 1.7 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Pkinase PF00069.25 KXH37199.1 - 1e-37 129.9 0.3 7.2e-23 81.3 0.2 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXH37199.1 - 4.3e-12 45.9 0.4 6.7e-10 38.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXH37199.1 - 0.088 11.6 0.0 0.14 10.9 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase T2SSM PF04612.12 KXH37200.1 - 0.058 13.5 5.4 0.22 11.6 5.6 1.7 1 1 0 1 1 1 0 Type II secretion system (T2SS), protein M Ndc1_Nup PF09531.10 KXH37200.1 - 4.8 5.7 6.7 5.1 5.7 6.7 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Fungal_trans PF04082.18 KXH37201.1 - 1.4e-25 89.9 0.0 2.8e-25 88.8 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH37201.1 - 2.1e-09 37.3 10.9 3.3e-09 36.7 10.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Kri1_C PF12936.7 KXH37202.1 - 1.3e-28 99.0 0.1 1.3e-28 99.0 0.1 4.2 5 0 0 5 5 5 1 KRI1-like family C-terminal Kri1 PF05178.12 KXH37202.1 - 6.9e-28 97.2 22.6 6.9e-28 97.2 22.6 5.6 6 1 0 6 6 6 1 KRI1-like family Ras PF00071.22 KXH37203.1 - 1.9e-56 190.1 0.0 2.8e-56 189.6 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXH37203.1 - 4.5e-33 114.0 0.0 7.6e-33 113.3 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXH37203.1 - 7.7e-13 48.3 0.0 1.2e-12 47.6 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KXH37203.1 - 4.3e-05 23.1 0.0 9.7e-05 22.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KXH37203.1 - 0.00077 18.9 0.0 0.0012 18.2 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KXH37203.1 - 0.0013 18.8 0.0 0.0024 17.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KXH37203.1 - 0.007 16.8 0.0 0.02 15.3 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain zf-C3HC4_3 PF13920.6 KXH37203.1 - 0.012 15.5 11.7 0.019 14.8 11.7 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 KXH37203.1 - 3.2 7.7 7.9 6 6.8 7.9 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein RecO_N_2 PF13114.6 KXH37204.1 - 0.14 11.9 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 RecO N terminal adh_short PF00106.25 KXH37205.1 - 1.3e-37 129.2 1.6 3.1e-37 128.0 1.6 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXH37205.1 - 7.3e-28 97.7 3.6 1.2e-27 97.0 3.6 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH37205.1 - 7.9e-14 52.0 1.7 1.1e-13 51.5 1.7 1.2 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 KXH37205.1 - 1.6e-08 34.8 0.2 9.7e-08 32.3 0.1 1.9 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 KXH37205.1 - 2.5e-07 30.4 0.1 3.5e-07 29.9 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KXH37205.1 - 2.9e-06 27.3 2.0 3.9e-06 26.9 1.2 1.6 2 0 0 2 2 2 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KXH37205.1 - 0.0093 15.1 0.1 0.014 14.6 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KXH37205.1 - 0.01 15.2 0.4 0.032 13.6 0.4 1.7 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase Cwf_Cwc_15 PF04889.12 KXH37206.1 - 7.4e-88 294.4 22.8 8.3e-88 294.3 22.8 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein CDC27 PF09507.10 KXH37206.1 - 0.0077 15.7 14.8 0.0095 15.4 14.8 1.1 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 YL1 PF05764.13 KXH37206.1 - 0.012 15.8 23.5 0.015 15.4 23.5 1.3 1 0 0 1 1 1 0 YL1 nuclear protein BUD22 PF09073.10 KXH37206.1 - 0.5 9.6 22.1 0.62 9.3 22.1 1.2 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 KXH37206.1 - 0.51 8.6 21.5 0.61 8.3 21.5 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 KXH37206.1 - 0.74 9.2 25.9 0.89 8.9 25.9 1.2 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 KXH37206.1 - 1 7.5 28.3 1.1 7.3 28.3 1.1 1 0 0 1 1 1 0 Nop14-like family Hid1 PF12722.7 KXH37206.1 - 1.2 7.2 4.4 1.3 7.1 4.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Nop53 PF07767.11 KXH37206.1 - 1.7 7.9 23.4 2.6 7.3 23.4 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) AAA_11 PF13086.6 KXH37206.1 - 1.9 8.2 5.3 2.2 8.0 5.3 1.2 1 0 0 1 1 1 0 AAA domain DUF3381 PF11861.8 KXH37206.1 - 3.6 7.4 20.1 6.7 6.5 20.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) SAPS PF04499.15 KXH37206.1 - 5 5.8 10.8 6.1 5.5 10.8 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RR_TM4-6 PF06459.12 KXH37206.1 - 6.3 6.5 11.4 8.7 6.1 11.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RNase_PH PF01138.21 KXH37207.1 - 1e-23 84.3 0.0 1.7e-23 83.6 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KXH37207.1 - 4.4e-08 33.0 0.0 7.2e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Arf PF00025.21 KXH37208.1 - 1.6e-40 138.4 0.0 2.5e-40 137.8 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 KXH37208.1 - 1.9e-15 56.9 0.0 2e-10 40.4 0.0 2.0 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 KXH37208.1 - 1.5e-10 40.9 0.0 6.5e-10 38.8 0.0 1.8 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KXH37208.1 - 6e-10 39.4 0.0 1.3e-09 38.3 0.0 1.6 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 KXH37208.1 - 8.4e-08 31.8 0.0 1e-07 31.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KXH37208.1 - 2.7e-07 30.2 0.0 1e-06 28.3 0.0 1.7 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 KXH37208.1 - 0.00014 21.5 0.3 0.00043 19.9 0.3 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KXH37208.1 - 0.00053 20.1 0.0 0.00081 19.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase NACHT PF05729.12 KXH37208.1 - 0.052 13.5 0.0 0.097 12.6 0.0 1.5 1 1 0 1 1 1 0 NACHT domain NUDIX PF00293.28 KXH37209.1 - 2.6e-16 59.8 0.0 5.6e-16 58.8 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.11 KXH37209.1 - 2.8e-14 53.6 0.0 1e-13 51.8 0.0 1.9 2 1 0 2 2 2 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.11 KXH37209.1 - 0.00038 20.1 0.4 0.00078 19.0 0.4 1.4 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain MFS_1 PF07690.16 KXH37210.1 - 4.5e-23 81.7 43.3 1.1e-22 80.5 43.0 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF3464 PF11947.8 KXH37210.1 - 1.5 8.5 3.6 50 3.6 0.3 3.1 3 0 0 3 3 3 0 Photosynthesis affected mutant 68 DUF812 PF05667.11 KXH37211.1 - 0.00063 18.8 3.1 0.0008 18.4 3.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) PHD PF00628.29 KXH37211.1 - 0.028 14.3 11.6 0.047 13.6 11.6 1.4 1 0 0 1 1 1 0 PHD-finger CENP-F_leu_zip PF10473.9 KXH37211.1 - 0.091 12.8 8.3 0.29 11.1 8.3 1.8 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Cnn_1N PF07989.11 KXH37211.1 - 0.14 12.3 2.9 5 7.3 0.6 2.4 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 Nucleo_P87 PF07267.11 KXH37211.1 - 1.5 7.6 8.0 2.1 7.1 8.0 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 TMF_DNA_bd PF12329.8 KXH37211.1 - 2.9 8.0 6.9 28 4.8 0.1 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Zf_RING PF16744.5 KXH37211.1 - 9.1 6.5 13.1 1.4 9.1 5.3 2.4 1 1 1 2 2 2 0 KIAA1045 RING finger Isochorismatase PF00857.20 KXH37212.1 - 9.5e-10 38.9 0.0 2.1e-09 37.8 0.0 1.5 1 1 1 2 2 2 1 Isochorismatase family PQ-loop PF04193.14 KXH37213.1 - 7.5e-41 137.7 8.3 5.1e-20 71.0 1.6 2.6 2 0 0 2 2 2 2 PQ loop repeat 7tm_1 PF00001.21 KXH37213.1 - 0.1 11.9 0.0 0.32 10.3 0.0 1.8 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) MtN3_slv PF03083.16 KXH37213.1 - 0.18 11.9 0.2 0.18 11.9 0.2 2.3 2 1 0 2 2 2 0 Sugar efflux transporter for intercellular exchange MFS_1 PF07690.16 KXH37214.1 - 1.3e-18 67.1 33.4 1.3e-18 67.1 33.4 3.1 1 1 2 3 3 3 2 Major Facilitator Superfamily OATP PF03137.20 KXH37214.1 - 0.68 8.1 7.9 0.033 12.5 1.3 2.1 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Catalase PF00199.19 KXH37215.1 - 1.9e-192 639.5 0.8 2.6e-192 639.1 0.8 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 KXH37215.1 - 1.5e-09 37.9 0.0 3.3e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 Catalase-related immune-responsive Ribosomal_60s PF00428.19 KXH37217.1 - 0.0028 18.2 9.8 0.0055 17.3 9.8 1.4 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF2457 PF10446.9 KXH37217.1 - 0.02 14.0 3.6 0.027 13.6 3.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Radial_spoke PF04712.12 KXH37217.1 - 0.022 13.7 1.6 0.025 13.5 1.6 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein FAM176 PF14851.6 KXH37217.1 - 0.023 14.4 0.0 0.03 14.0 0.0 1.2 1 0 0 1 1 1 0 FAM176 family DUF5566 PF17721.1 KXH37217.1 - 0.091 13.0 0.0 0.14 12.4 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5566) DUF4530 PF15039.6 KXH37217.1 - 9.9 6.3 13.6 0.77 9.9 7.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4530) Arf PF00025.21 KXH37218.1 - 1e-73 246.5 0.0 1.2e-73 246.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KXH37218.1 - 1.2e-14 54.6 0.0 1.6e-14 54.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KXH37218.1 - 1.5e-13 50.6 0.0 1.9e-13 50.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 KXH37218.1 - 4.4e-12 45.8 0.3 5.7e-08 32.3 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 KXH37218.1 - 5.5e-11 42.3 0.0 6.5e-11 42.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KXH37218.1 - 2e-08 33.9 0.0 2.4e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KXH37218.1 - 7.1e-07 29.3 0.0 1.2e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KXH37218.1 - 0.00018 21.1 0.0 0.015 14.8 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 KXH37218.1 - 0.01 15.4 0.8 0.045 13.3 0.8 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B Toprim_4 PF13662.6 KXH37218.1 - 0.074 13.5 0.0 1.5 9.4 0.0 2.3 2 0 0 2 2 2 0 Toprim domain AAA_18 PF13238.6 KXH37218.1 - 0.14 12.7 0.1 0.22 12.1 0.1 1.5 1 1 0 1 1 1 0 AAA domain HNH_repeat PF18780.1 KXH37218.1 - 0.2 11.5 0.5 0.33 10.8 0.5 1.4 1 0 0 1 1 1 0 Homing endonuclease repeat Ribosomal_L39 PF00832.20 KXH37219.1 - 9e-22 76.4 9.4 1.1e-21 76.1 9.4 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein Skp1 PF01466.19 KXH37220.1 - 1.2e-29 102.2 0.4 3.4e-29 100.7 0.4 1.8 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 KXH37220.1 - 6.9e-21 74.2 0.3 1.7e-20 72.9 0.2 1.8 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain LUD_dom PF02589.15 KXH37220.1 - 0.091 12.5 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 LUD domain Glyco_transf_22 PF03901.17 KXH37221.1 - 7.2e-60 203.4 22.4 8.9e-60 203.1 22.4 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family PMT_2 PF13231.6 KXH37221.1 - 0.015 15.5 8.3 0.015 15.5 8.3 2.3 2 0 0 2 2 2 0 Dolichyl-phosphate-mannose-protein mannosyltransferase PAN_4 PF14295.6 KXH37222.1 - 0.092 12.7 0.8 0.2 11.6 0.8 1.6 1 0 0 1 1 1 0 PAN domain Tic110 PF16940.5 KXH37222.1 - 0.18 10.3 2.7 0.23 9.9 2.7 1.1 1 0 0 1 1 1 0 Chloroplast envelope transporter Sh_2 PF17512.2 KXH37222.1 - 0.41 10.4 5.6 0.89 9.3 5.6 1.6 1 1 0 1 1 1 0 Metapneumovirus Small hydrophobic protein RXLR PF16810.5 KXH37225.1 - 0.28 11.6 3.3 0.34 11.3 3.3 1.2 1 0 0 1 1 1 0 RXLR phytopathogen effector protein, Avirulence activity Sporozoite_P67 PF05642.11 KXH37225.1 - 0.95 7.5 6.9 1.1 7.3 6.9 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Nnf1 PF03980.14 KXH37226.1 - 1.6e-34 118.6 1.1 1.6e-34 118.6 1.1 2.0 2 0 0 2 2 2 1 Nnf1 TPR_MLP1_2 PF07926.12 KXH37226.1 - 0.0044 17.1 0.3 0.0044 17.1 0.3 2.7 4 0 0 4 4 4 1 TPR/MLP1/MLP2-like protein MAP65_ASE1 PF03999.12 KXH37226.1 - 0.024 13.4 0.1 0.024 13.4 0.1 2.0 2 0 0 2 2 2 0 Microtubule associated protein (MAP65/ASE1 family) Snapin_Pallidin PF14712.6 KXH37226.1 - 0.07 13.5 0.9 0.07 13.5 0.9 2.9 3 1 0 3 3 3 0 Snapin/Pallidin FliT PF05400.13 KXH37226.1 - 3.2 8.6 7.3 3 8.7 1.6 3.1 3 0 0 3 3 3 0 Flagellar protein FliT 40S_SA_C PF16122.5 KXH37228.1 - 1.7 10.1 7.8 1.8 10.0 1.7 2.5 1 1 0 2 2 2 0 40S ribosomal protein SA C-terminus WLM PF08325.10 KXH37254.1 - 5.9e-57 192.8 0.0 1.5e-56 191.5 0.0 1.7 1 0 0 1 1 1 1 WLM domain zf-RanBP PF00641.18 KXH37254.1 - 0.00045 19.5 2.8 0.00045 19.5 2.8 2.1 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others DUF728 PF05304.12 KXH37254.1 - 0.15 11.9 0.1 0.33 10.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF728) Peptidase_M54 PF07998.11 KXH37254.1 - 0.22 11.5 0.0 0.31 11.0 0.0 1.1 1 0 0 1 1 1 0 Peptidase family M54 Asp PF00026.23 KXH37255.1 - 3.2e-69 233.8 7.5 3.7e-69 233.6 7.5 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KXH37255.1 - 7.3e-11 42.6 4.4 1.2e-08 35.4 4.4 2.4 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Glyco_hydro_61 PF03443.14 KXH37260.1 - 1e-58 198.7 0.1 1.2e-58 198.5 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Myb_DNA-binding PF00249.31 KXH37263.1 - 5.5e-07 29.7 0.0 8.6e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KXH37263.1 - 0.00017 21.7 0.0 0.00028 21.1 0.0 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain ADH_N PF08240.12 KXH37266.1 - 2.8e-27 94.8 0.4 4.5e-27 94.1 0.4 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXH37266.1 - 1.6e-23 83.1 0.1 2.5e-23 82.5 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KXH37266.1 - 8.1e-08 32.0 1.6 1.5e-07 31.1 1.6 1.5 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KXH37266.1 - 8.4e-07 30.1 0.0 1.9e-06 29.0 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FAD_binding_3 PF01494.19 KXH37266.1 - 4.4e-05 22.9 0.2 6.2e-05 22.4 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 KXH37266.1 - 0.0072 15.6 0.1 0.01 15.1 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AIRS PF00586.24 KXH37266.1 - 0.023 15.3 0.2 0.063 13.9 0.2 1.7 1 0 0 1 1 1 0 AIR synthase related protein, N-terminal domain Shikimate_DH PF01488.20 KXH37266.1 - 0.025 14.6 0.2 0.043 13.9 0.2 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase AlaDh_PNT_C PF01262.21 KXH37266.1 - 0.025 13.9 3.7 0.039 13.2 3.7 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ADH_N_assoc PF13823.6 KXH37266.1 - 0.031 14.2 0.0 0.074 13.0 0.0 1.7 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-associated tRNA_int_endo PF01974.17 KXH37267.1 - 0.3 11.2 1.3 3.2 7.9 0.1 2.6 3 0 0 3 3 3 0 tRNA intron endonuclease, catalytic C-terminal domain PrpF PF04303.13 KXH37269.1 - 3.1e-82 276.5 0.0 3.7e-82 276.2 0.0 1.0 1 0 0 1 1 1 1 PrpF protein DAPG_hydrolase PF18089.1 KXH37270.1 - 2e-79 266.3 0.9 2.5e-79 266.0 0.9 1.1 1 0 0 1 1 1 1 DAPG hydrolase PhiG domain Lactonase PF10282.9 KXH37271.1 - 1.3e-19 70.6 0.6 2.8e-19 69.6 0.6 1.6 1 1 0 1 1 1 1 Lactonase, 7-bladed beta-propeller PheRS_DBD1 PF18552.1 KXH37271.1 - 0.0036 17.0 0.0 2.8 7.8 0.0 2.4 2 0 0 2 2 2 2 PheRS DNA binding domain 1 adh_short PF00106.25 KXH37272.1 - 1.8e-23 83.0 0.0 2.8e-23 82.4 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXH37272.1 - 8e-14 51.7 0.0 1.2e-13 51.2 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KXH37272.1 - 7.6e-06 25.6 0.0 1.3e-05 24.8 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KXH37272.1 - 3.9e-05 23.7 0.2 5.8e-05 23.1 0.0 1.4 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.6 KXH37272.1 - 0.02 14.8 0.1 0.027 14.4 0.1 1.3 1 1 0 1 1 1 0 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KXH37272.1 - 0.077 12.4 0.0 0.19 11.1 0.0 1.7 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase Cupin_2 PF07883.11 KXH37273.1 - 5.8e-15 54.8 0.1 9.5e-15 54.1 0.1 1.4 1 0 0 1 1 1 1 Cupin domain ARD PF03079.14 KXH37273.1 - 8e-05 22.9 0.2 0.00016 21.9 0.0 1.5 2 0 0 2 2 2 1 ARD/ARD' family AraC_binding PF02311.19 KXH37273.1 - 0.00011 22.1 0.0 0.00016 21.6 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.22 KXH37273.1 - 0.00019 21.1 0.0 0.00025 20.7 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.12 KXH37273.1 - 0.0015 18.1 0.1 0.0029 17.3 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_6 PF12852.7 KXH37273.1 - 0.0029 17.3 0.0 0.0036 17.1 0.0 1.2 1 0 0 1 1 1 1 Cupin JmjC PF02373.22 KXH37273.1 - 0.0076 16.7 0.0 0.013 15.9 0.0 1.4 1 0 0 1 1 1 1 JmjC domain, hydroxylase GFA PF04828.14 KXH37274.1 - 0.00035 20.9 8.0 0.0036 17.6 0.6 3.0 2 1 0 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme OPT PF03169.15 KXH37275.1 - 3e-81 273.9 50.4 3.5e-81 273.7 50.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein HET PF06985.11 KXH37276.1 - 1.3e-24 87.2 0.5 2.5e-24 86.3 0.5 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Glyco_hydro_76 PF03663.14 KXH37277.1 - 1.8e-141 471.9 7.0 2.2e-141 471.6 7.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 EphA2_TM PF14575.6 KXH37278.1 - 9.6e-06 26.4 0.0 1.3e-05 26.0 0.0 1.3 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain SARAF PF06682.12 KXH37278.1 - 4.7e-05 23.2 0.7 5.1e-05 23.1 0.7 1.1 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis Adeno_E3_CR2 PF02439.15 KXH37278.1 - 0.00021 21.0 4.7 0.00033 20.4 4.7 1.2 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 RIFIN PF02009.16 KXH37278.1 - 0.0021 18.0 0.3 0.0029 17.5 0.3 1.1 1 0 0 1 1 1 1 Rifin DAG1 PF05454.11 KXH37278.1 - 0.016 14.6 0.4 0.025 14.0 0.4 1.3 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) Amnionless PF14828.6 KXH37278.1 - 0.026 13.4 0.0 0.026 13.3 0.0 1.0 1 0 0 1 1 1 0 Amnionless Herpes_gE PF02480.16 KXH37278.1 - 0.055 12.2 0.0 0.059 12.1 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Shisa PF13908.6 KXH37278.1 - 0.058 13.6 0.0 0.074 13.3 0.0 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF4690 PF15756.5 KXH37278.1 - 0.072 13.7 0.8 0.11 13.1 0.8 1.4 1 0 0 1 1 1 0 Small Novel Rich in Cartilage Syndecan PF01034.20 KXH37278.1 - 0.63 10.0 3.6 1.2 9.1 3.6 1.4 1 0 0 1 1 1 0 Syndecan domain Fungal_trans_2 PF11951.8 KXH37279.1 - 2.8e-25 88.9 0.1 4.5e-25 88.3 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH37279.1 - 7.7e-08 32.3 8.3 1.3e-07 31.6 8.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Transp_cyt_pur PF02133.15 KXH37280.1 - 6.8e-78 262.4 37.9 7.7e-78 262.2 37.9 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Aminotran_1_2 PF00155.21 KXH37281.1 - 2.8e-13 49.8 0.0 5.4e-13 48.8 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II COesterase PF00135.28 KXH37282.1 - 3.1e-79 267.2 0.0 5e-79 266.5 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family DUF3176 PF11374.8 KXH37282.1 - 1.1e-33 115.6 0.8 3.2e-33 114.1 0.8 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) Abhydrolase_3 PF07859.13 KXH37282.1 - 8.4e-06 25.8 0.0 0.038 13.8 0.0 2.5 2 0 0 2 2 2 2 alpha/beta hydrolase fold Lactate_perm PF02652.14 KXH37282.1 - 0.12 11.0 0.2 0.19 10.4 0.2 1.1 1 0 0 1 1 1 0 L-lactate permease MFS_1 PF07690.16 KXH37283.1 - 6.5e-30 104.2 24.1 7.9e-30 104.0 24.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily HpcH_HpaI PF03328.14 KXH37284.1 - 4e-22 78.5 0.5 1.1e-21 77.0 0.2 1.7 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family CODH_A_N PF18537.1 KXH37284.1 - 0.037 14.0 0.1 0.29 11.2 0.0 2.4 2 1 0 2 2 2 0 Carbon monoxide dehydrogenase subunit alpha N-terminal domain Abhydrolase_6 PF12697.7 KXH37285.1 - 4.2e-15 56.9 0.0 6.1e-15 56.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXH37285.1 - 2.3e-11 43.8 0.0 3.6e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXH37285.1 - 2.5e-06 27.0 0.0 3.4e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 KXH37285.1 - 0.0041 16.9 0.0 0.0094 15.7 0.0 1.6 2 0 0 2 2 2 1 PGAP1-like protein Ser_hydrolase PF06821.13 KXH37285.1 - 0.038 13.8 0.0 0.078 12.8 0.0 1.5 1 0 0 1 1 1 0 Serine hydrolase DUF1057 PF06342.12 KXH37285.1 - 0.046 12.8 0.1 0.21 10.6 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1057) Ndr PF03096.14 KXH37285.1 - 0.057 12.1 0.0 0.16 10.6 0.0 1.6 2 0 0 2 2 2 0 Ndr family Fungal_trans PF04082.18 KXH37286.1 - 0.035 13.2 0.1 0.58 9.1 0.2 2.2 1 1 1 2 2 2 0 Fungal specific transcription factor domain Pkinase PF00069.25 KXH37287.1 - 1.9e-21 76.6 0.0 1.2e-13 51.0 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXH37287.1 - 4.7e-14 52.3 0.0 9.5e-14 51.3 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXH37288.1 - 4.4e-23 82.0 0.0 8.3e-23 81.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain HET PF06985.11 KXH37288.1 - 1.8e-19 70.5 0.0 4e-19 69.4 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) tRNA-synt_1b PF00579.25 KXH37288.1 - 1.2e-17 64.2 0.0 2.1e-17 63.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Pkinase_Tyr PF07714.17 KXH37288.1 - 3.3e-17 62.6 0.0 5.7e-17 61.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase adh_short_C2 PF13561.6 KXH37289.1 - 6.3e-53 179.7 0.0 7.2e-53 179.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXH37289.1 - 4.8e-46 156.7 0.0 5.7e-46 156.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXH37289.1 - 1.8e-12 47.5 0.0 2.6e-12 47.0 0.0 1.2 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 KXH37289.1 - 0.024 14.0 0.0 0.047 13.0 0.0 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF1776 PF08643.10 KXH37289.1 - 0.027 13.8 0.0 0.27 10.6 0.0 2.2 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) CdiI_2 PF18593.1 KXH37289.1 - 0.099 13.3 0.0 1.3 9.7 0.0 2.2 2 0 0 2 2 2 0 CdiI immunity protein DUF3830 PF12903.7 KXH37289.1 - 0.3 10.8 1.4 1.8 8.2 0.5 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF3830) UPF0086 PF01868.16 KXH37291.1 - 9.4e-28 96.0 0.0 1.4e-27 95.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function UPF0086 Acyltransferase PF01553.21 KXH37292.1 - 5.5e-17 61.7 0.0 1.1e-16 60.7 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase RAP PF08373.10 KXH37292.1 - 0.13 12.4 0.0 0.33 11.1 0.0 1.6 1 0 0 1 1 1 0 RAP domain Pantoate_ligase PF02569.15 KXH37293.1 - 9.1e-93 310.3 0.0 1.1e-92 310.0 0.0 1.1 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase TFIIA PF03153.13 KXH37294.1 - 0.66 9.9 12.5 1.2 9.1 12.5 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Macoilin PF09726.9 KXH37294.1 - 0.99 7.9 6.2 1.5 7.3 6.2 1.1 1 0 0 1 1 1 0 Macoilin family MAP65_ASE1 PF03999.12 KXH37294.1 - 1 8.0 6.4 1.5 7.4 6.4 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Spt20 PF12090.8 KXH37294.1 - 1 8.9 11.7 1.9 8.0 11.7 1.4 1 0 0 1 1 1 0 Spt20 family Zip PF02535.22 KXH37294.1 - 9.1 5.4 6.2 14 4.7 6.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter HAD_2 PF13419.6 KXH37295.1 - 6.3e-17 62.2 0.0 2.5e-08 34.2 0.0 2.2 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KXH37295.1 - 1.2e-06 29.0 0.0 7.2e-05 23.2 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KXH37295.1 - 0.0011 19.0 0.0 0.002 18.1 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like NT5C PF06941.12 KXH37295.1 - 0.041 13.8 0.0 0.21 11.5 0.0 2.0 1 1 0 1 1 1 0 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) TPR_2 PF07719.17 KXH37296.1 - 6.6e-05 22.7 2.6 0.022 14.8 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 KXH37296.1 - 0.00024 20.7 1.1 0.0004 20.0 0.2 1.9 2 0 0 2 2 2 1 TPR repeat TPR_12 PF13424.6 KXH37296.1 - 0.00094 19.4 0.3 0.0025 18.0 0.3 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 KXH37296.1 - 0.002 17.9 3.2 0.069 13.0 0.0 3.4 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 KXH37296.1 - 0.05 14.1 0.5 0.05 14.1 0.5 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat SLATT_5 PF18160.1 KXH37296.1 - 0.14 11.5 0.1 0.24 10.7 0.1 1.3 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 ANAPC3 PF12895.7 KXH37296.1 - 0.15 12.3 1.5 0.63 10.3 1.5 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 KXH37296.1 - 1.1 10.3 6.5 2 9.4 0.0 3.5 3 1 0 3 3 3 0 Tetratricopeptide repeat PLDc PF00614.22 KXH37297.1 - 4.1e-15 55.2 2.3 5.9e-07 29.4 0.1 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 KXH37297.1 - 7.7e-15 55.0 0.0 3.8e-05 23.6 0.0 3.6 3 0 0 3 3 3 3 PLD-like domain GLTP PF08718.11 KXH37299.1 - 1.3e-47 161.8 0.0 1.7e-47 161.5 0.0 1.1 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) Dapper PF15268.6 KXH37302.1 - 0.76 8.6 7.4 0.99 8.2 7.4 1.1 1 0 0 1 1 1 0 Dapper PMI_typeI PF01238.21 KXH37303.1 - 1.9e-72 244.5 0.0 7.1e-71 239.4 0.0 2.0 1 1 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.11 KXH37303.1 - 9.5e-06 25.2 0.2 0.0033 17.1 0.1 2.5 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.19 KXH37303.1 - 0.0003 20.7 0.0 0.0033 17.3 0.0 2.2 2 0 0 2 2 2 1 AraC-like ligand binding domain Cupin_3 PF05899.12 KXH37303.1 - 0.0074 16.0 0.5 0.11 12.2 0.2 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF861) Sulfate_transp PF00916.20 KXH37304.1 - 2.7e-105 352.2 14.3 3.4e-105 351.9 14.3 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KXH37304.1 - 1.1e-08 34.7 0.0 2e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 KXH37304.1 - 3.6e-07 30.5 14.6 2.8e-05 24.5 6.1 2.7 2 1 0 2 2 2 2 Molybdate transporter of MFS superfamily Cu-oxidase_2 PF07731.14 KXH37305.1 - 1.6e-26 92.6 0.7 3.7e-24 85.0 0.7 2.7 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 KXH37305.1 - 1.5e-17 63.7 0.1 4.2e-17 62.3 0.0 1.9 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.22 KXH37305.1 - 0.00037 20.7 0.0 0.00098 19.3 0.0 1.8 1 1 0 1 1 1 1 Multicopper oxidase DUF3176 PF11374.8 KXH37307.1 - 3.8e-28 97.8 3.7 4.5e-28 97.6 0.2 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF3176) Methyltransf_23 PF13489.6 KXH37308.1 - 2.9e-16 59.7 0.0 5.7e-16 58.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH37308.1 - 1.5e-10 41.6 0.0 3.3e-10 40.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH37308.1 - 5.6e-10 39.2 0.0 2.2e-09 37.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH37308.1 - 6.5e-07 30.0 0.0 5.1e-06 27.1 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH37308.1 - 1.2e-06 29.1 0.0 2.5e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXH37308.1 - 0.0017 18.0 0.0 0.01 15.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.18 KXH37308.1 - 0.013 14.8 0.0 0.025 13.9 0.0 1.5 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_16 PF10294.9 KXH37308.1 - 0.013 15.2 0.0 0.021 14.6 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase PrmA PF06325.13 KXH37308.1 - 0.071 12.5 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.17 KXH37308.1 - 0.079 12.4 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Ubie_methyltran PF01209.18 KXH37308.1 - 0.16 11.3 0.0 0.36 10.1 0.0 1.5 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family FtsJ PF01728.19 KXH37308.1 - 0.21 11.7 0.0 0.36 10.9 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Metallophos PF00149.28 KXH37309.1 - 4.4e-14 53.5 0.2 6.3e-14 53.0 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KXH37309.1 - 0.061 13.5 0.0 0.19 11.9 0.0 2.0 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain NmrA PF05368.13 KXH37310.1 - 8.9e-16 58.2 0.0 1.1e-15 57.9 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXH37310.1 - 5.6e-10 39.4 0.0 1e-09 38.5 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KXH37310.1 - 0.00041 19.9 0.0 0.0016 17.9 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Pyr_redox_3 PF13738.6 KXH37311.1 - 3e-18 66.1 0.0 1.3e-17 64.0 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KXH37311.1 - 6.7e-15 54.5 0.0 1.8e-13 49.8 0.0 2.2 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KXH37311.1 - 2.9e-13 49.7 0.0 7.6e-12 45.0 0.0 2.5 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KXH37311.1 - 1.1e-11 44.6 0.0 4.5e-10 39.3 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXH37311.1 - 3.8e-07 30.2 0.2 7.7e-06 26.0 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXH37311.1 - 1.3e-05 25.0 0.0 0.04 13.5 0.0 2.6 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 KXH37311.1 - 0.0016 19.0 0.7 1.2 9.8 0.1 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXH37311.1 - 0.0021 17.3 0.4 0.007 15.6 0.0 1.8 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.6 KXH37311.1 - 0.0056 16.7 0.0 0.23 11.5 0.0 2.9 2 1 0 2 2 2 1 FAD-NAD(P)-binding HI0933_like PF03486.14 KXH37311.1 - 0.024 13.4 0.1 1.2 7.8 0.0 2.4 2 0 0 2 2 2 0 HI0933-like protein GIDA PF01134.22 KXH37311.1 - 0.26 10.3 1.0 16 4.5 0.6 3.1 3 0 0 3 3 3 0 Glucose inhibited division protein A SnoaL PF07366.12 KXH37312.1 - 0.021 14.6 0.0 0.039 13.7 0.0 1.5 1 1 0 1 1 1 0 SnoaL-like polyketide cyclase Zn_clus PF00172.18 KXH37313.1 - 3.4e-06 27.1 12.0 5.9e-06 26.3 12.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain YlbD_coat PF14071.6 KXH37313.1 - 0.0087 16.3 0.1 0.092 13.0 0.0 2.2 2 0 0 2 2 2 1 Putative coat protein Fungal_trans PF04082.18 KXH37313.1 - 0.41 9.6 4.8 0.17 10.9 0.1 2.6 2 1 1 3 3 3 0 Fungal specific transcription factor domain DLH PF01738.18 KXH37315.1 - 2e-26 92.9 0.0 2.3e-26 92.7 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family adh_short_C2 PF13561.6 KXH37316.1 - 8.4e-60 202.2 0.3 9.8e-60 202.0 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXH37316.1 - 1.2e-46 158.7 0.5 1.4e-46 158.4 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXH37316.1 - 7.3e-16 58.6 0.1 1.2e-15 57.9 0.1 1.2 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 KXH37316.1 - 0.00074 18.6 0.2 0.0023 17.0 0.2 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family HATPase_c PF02518.26 KXH37316.1 - 0.063 13.8 0.0 0.15 12.6 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase EHN PF06441.12 KXH37317.1 - 6.1e-28 97.4 0.2 1.3e-27 96.3 0.2 1.6 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 KXH37317.1 - 1.5e-06 28.1 0.0 2.4e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Flavi_M PF01004.19 KXH37317.1 - 0.019 14.7 0.0 0.038 13.8 0.0 1.4 1 0 0 1 1 1 0 Flavivirus envelope glycoprotein M Abhydrolase_6 PF12697.7 KXH37317.1 - 0.04 14.5 0.4 0.54 10.8 0.2 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase family MFS_1 PF07690.16 KXH37318.1 - 1.4e-20 73.6 31.8 6.4e-19 68.1 23.3 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KXH37318.1 - 3.6e-08 32.7 5.1 6.6e-05 21.9 0.0 2.7 1 1 1 2 2 2 2 MFS_1 like family Cu_amine_oxid PF01179.20 KXH37319.1 - 9e-122 406.9 3.1 1.1e-121 406.6 3.1 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain DUF1965 PF09248.10 KXH37319.1 - 1e-09 38.0 1.9 1.9e-09 37.1 0.1 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF1965) Cu_amine_oxidN2 PF02727.16 KXH37319.1 - 0.056 13.7 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 Copper amine oxidase, N2 domain Git3 PF11710.8 KXH37320.1 - 4.6e-22 78.8 7.1 7.1e-22 78.2 7.1 1.2 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.21 KXH37320.1 - 5.2e-13 48.9 0.0 7.2e-13 48.5 0.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Dicty_CAR PF05462.11 KXH37320.1 - 2.6e-09 36.6 8.7 6.8e-08 32.0 6.2 2.1 2 0 0 2 2 2 2 Slime mold cyclic AMP receptor GPR_Gpa2_C PF11970.8 KXH37320.1 - 0.00043 20.3 0.4 0.0036 17.3 0.0 2.4 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term ADH_zinc_N PF00107.26 KXH37321.1 - 2.1e-23 82.7 0.3 3.5e-23 82.0 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXH37321.1 - 3.4e-20 72.0 0.1 8.1e-20 70.7 0.1 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KXH37321.1 - 0.00012 23.1 0.1 0.0029 18.7 0.0 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase SKG6 PF08693.10 KXH37322.1 - 0.0077 15.6 0.0 0.016 14.6 0.0 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain CFEM PF05730.11 KXH37322.1 - 0.0093 16.0 2.2 0.017 15.2 2.2 1.5 1 0 0 1 1 1 1 CFEM domain PGF-CTERM PF18204.1 KXH37322.1 - 0.17 11.9 1.5 0.44 10.6 1.5 1.7 1 0 0 1 1 1 0 PGF-CTERM motif Shisa PF13908.6 KXH37323.1 - 0.0047 17.2 0.5 0.0047 17.2 0.5 1.8 2 0 0 2 2 2 1 Wnt and FGF inhibitory regulator TMEM52 PF14979.6 KXH37323.1 - 0.019 14.9 1.2 0.046 13.7 1.2 1.6 1 0 0 1 1 1 0 Transmembrane 52 Rhabdo_glycop PF00974.18 KXH37323.1 - 0.098 11.1 5.2 0.97 7.8 1.2 2.2 2 0 0 2 2 2 0 Rhabdovirus spike glycoprotein TMEM154 PF15102.6 KXH37323.1 - 0.12 12.2 0.0 0.29 11.0 0.0 1.6 1 1 0 1 1 1 0 TMEM154 protein family L_HMGIC_fpl PF10242.9 KXH37323.1 - 0.37 11.0 5.0 6 7.0 0.3 2.3 2 0 0 2 2 2 0 Lipoma HMGIC fusion partner-like protein UPF0560 PF10577.9 KXH37323.1 - 0.38 9.2 1.4 0.56 8.6 1.4 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Glyco_hydro_71 PF03659.14 KXH37324.1 - 4.5e-138 460.2 2.7 4.5e-138 460.2 2.7 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 71 Aa_trans PF01490.18 KXH37325.1 - 1.3e-10 40.6 9.1 2.1e-10 39.9 9.1 1.3 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein HRI1 PF16815.5 KXH37326.1 - 2.4e-29 102.7 0.2 2.8e-29 102.5 0.2 1.0 1 0 0 1 1 1 1 Protein HRI1 Fungal_trans PF04082.18 KXH37327.1 - 1.6e-31 109.3 6.2 2.3e-21 76.0 0.4 2.4 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH37327.1 - 6.4e-06 26.2 8.7 1.6e-05 25.0 8.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain IL15 PF02372.15 KXH37327.1 - 0.076 13.0 0.3 0.21 11.6 0.3 1.7 1 0 0 1 1 1 0 Interleukin 15 Nop53 PF07767.11 KXH37328.1 - 5.1e-107 358.7 26.2 6e-107 358.5 26.2 1.0 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) Ras PF00071.22 KXH37329.1 - 9.4e-52 174.9 1.0 1.3e-51 174.4 1.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXH37329.1 - 3e-31 108.1 0.3 5.2e-31 107.4 0.3 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXH37329.1 - 2e-17 63.2 0.6 2.5e-17 62.9 0.6 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KXH37329.1 - 4.6e-08 33.1 0.2 9.1e-08 32.2 0.2 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KXH37329.1 - 3.6e-07 29.9 0.3 3.7e-06 26.6 0.3 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 KXH37329.1 - 2e-06 27.4 0.3 3.7e-06 26.5 0.3 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KXH37329.1 - 4.6e-05 22.9 0.7 6.2e-05 22.5 0.7 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KXH37329.1 - 0.00013 21.9 1.9 0.11 12.5 0.2 2.2 1 1 1 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 KXH37329.1 - 0.0037 17.4 1.1 0.033 14.3 1.1 2.3 1 1 0 1 1 1 1 Dynamin family Septin PF00735.18 KXH37329.1 - 0.022 14.0 0.1 0.046 13.0 0.1 1.4 1 0 0 1 1 1 0 Septin AAA_28 PF13521.6 KXH37329.1 - 0.026 14.8 0.0 1.1 9.4 0.0 2.2 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 KXH37329.1 - 0.033 13.9 0.1 0.049 13.4 0.1 1.6 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation FlgH PF02107.16 KXH37329.1 - 0.048 13.3 0.4 0.048 13.3 0.4 1.7 2 0 0 2 2 2 0 Flagellar L-ring protein TIR_2 PF13676.6 KXH37329.1 - 0.069 13.8 0.1 0.13 12.9 0.1 1.4 1 0 0 1 1 1 0 TIR domain TniB PF05621.11 KXH37329.1 - 0.069 12.5 0.0 0.31 10.4 0.0 2.0 2 0 0 2 2 2 0 Bacterial TniB protein AAA_16 PF13191.6 KXH37329.1 - 0.072 13.5 0.0 0.11 12.9 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain Kei1 PF08552.11 KXH37330.1 - 2.9e-61 206.7 2.5 3.6e-61 206.4 2.5 1.1 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 SPC12 PF06645.13 KXH37330.1 - 2.7 8.1 8.6 0.12 12.5 2.4 2.0 2 1 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) NIR_SIR PF01077.22 KXH37331.1 - 2.9e-55 186.1 0.1 1.8e-49 167.3 0.1 2.6 3 0 0 3 3 3 2 Nitrite and sulphite reductase 4Fe-4S domain Flavodoxin_1 PF00258.25 KXH37331.1 - 2.1e-31 109.1 0.0 5.1e-31 107.8 0.0 1.7 1 0 0 1 1 1 1 Flavodoxin NIR_SIR_ferr PF03460.17 KXH37331.1 - 7.5e-31 105.8 0.0 1.2e-15 57.0 0.0 2.5 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain POR_N PF01855.19 KXH37331.1 - 9.2e-09 35.4 0.1 2e-08 34.3 0.1 1.5 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg PFOR_II PF17147.4 KXH37331.1 - 4.5e-06 26.9 0.0 1.2e-05 25.6 0.0 1.8 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II RHH_7 PF16777.5 KXH37331.1 - 0.09 13.2 0.0 0.34 11.3 0.0 2.0 1 0 0 1 1 1 0 Transcriptional regulator, RHH-like, CopG Pyr_redox_2 PF07992.14 KXH37332.1 - 3.9e-42 144.5 0.0 5.6e-42 144.0 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXH37332.1 - 2.5e-15 56.8 0.0 2e-10 41.1 0.0 3.9 4 0 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.32 KXH37332.1 - 6.6e-06 25.3 0.2 1.4e-05 24.3 0.2 1.6 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KXH37332.1 - 8.2e-05 22.2 0.4 0.00025 20.7 0.4 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 KXH37332.1 - 0.00064 20.1 0.1 0.0015 19.0 0.1 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 KXH37332.1 - 0.00088 18.7 0.8 0.002 17.5 0.8 1.6 1 0 0 1 1 1 1 EF hand Flavin_Reduct PF01613.18 KXH37332.1 - 0.027 14.5 0.0 0.047 13.7 0.0 1.3 1 0 0 1 1 1 0 Flavin reductase like domain MGC-24 PF05283.11 KXH37332.1 - 0.076 13.5 0.0 0.15 12.5 0.0 1.4 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Pyr_redox_3 PF13738.6 KXH37332.1 - 0.17 11.1 0.0 1.4 8.1 0.0 2.2 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase PRK PF00485.18 KXH37333.1 - 3.1e-58 196.8 0.0 4.6e-58 196.2 0.0 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.6 KXH37333.1 - 5.4e-42 143.6 0.0 8.2e-42 143.0 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase AAA_18 PF13238.6 KXH37333.1 - 9.9e-06 26.1 0.0 2.5e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 KXH37333.1 - 2.9e-05 24.5 0.1 0.5 10.8 0.0 3.1 3 0 0 3 3 3 2 AAA domain CPT PF07931.12 KXH37333.1 - 5.2e-05 23.2 0.0 0.0001 22.2 0.0 1.5 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.6 KXH37333.1 - 6.7e-05 23.1 0.0 0.00062 19.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 KXH37333.1 - 0.0019 18.7 0.2 0.0094 16.5 0.1 2.0 2 0 0 2 2 2 1 ABC transporter Zeta_toxin PF06414.12 KXH37333.1 - 0.0058 15.9 0.0 0.014 14.7 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_29 PF13555.6 KXH37333.1 - 0.02 14.6 0.0 0.053 13.3 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain NB-ARC PF00931.22 KXH37333.1 - 0.029 13.6 0.0 0.055 12.6 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain DUF87 PF01935.17 KXH37333.1 - 0.07 13.2 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 Helicase HerA, central domain Cytidylate_kin PF02224.18 KXH37333.1 - 0.12 12.1 0.1 0.33 10.7 0.0 1.7 2 0 0 2 2 2 0 Cytidylate kinase dNK PF01712.19 KXH37333.1 - 0.15 11.9 0.0 8 6.3 0.0 2.4 2 1 0 2 2 2 0 Deoxynucleoside kinase NTPase_1 PF03266.15 KXH37333.1 - 0.16 11.9 0.0 1 9.3 0.0 2.1 2 0 0 2 2 2 0 NTPase CLTH PF10607.9 KXH37334.1 - 1.6e-31 109.2 0.0 2.7e-31 108.5 0.0 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 KXH37334.1 - 4.6e-09 35.9 0.0 1.1e-08 34.8 0.0 1.7 1 0 0 1 1 1 1 LisH Ribosomal_S8 PF00410.19 KXH37334.1 - 0.12 12.3 0.2 0.24 11.4 0.1 1.5 2 0 0 2 2 2 0 Ribosomal protein S8 ETC_C1_NDUFA4 PF04800.12 KXH37335.1 - 3.3e-37 126.6 2.3 5.3e-37 126.0 2.3 1.3 1 0 0 1 1 1 1 ETC complex I subunit conserved region Copper-bind PF00127.20 KXH37335.1 - 0.035 14.5 0.0 0.076 13.5 0.0 1.5 1 1 0 1 1 1 0 Copper binding proteins, plastocyanin/azurin family F1F0-ATPsyn_F PF10791.9 KXH37336.1 - 4.4e-41 139.3 0.1 5e-41 139.1 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi WRW PF10206.9 KXH37336.1 - 0.036 14.4 0.0 0.041 14.3 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial F1F0-ATP synthase, subunit f DUF3340 PF11818.8 KXH37337.1 - 0.059 13.5 2.5 0.11 12.6 2.5 1.4 1 0 0 1 1 1 0 C-terminal domain of tail specific protease (DUF3340) SMG1_N PF17229.2 KXH37339.1 - 0.48 11.2 3.7 0.47 11.2 2.3 1.6 2 0 0 2 2 2 0 Serine/threonine-protein kinase SMG1 N-terminal Sugar_tr PF00083.24 KXH37340.1 - 2.2e-77 260.9 27.5 2.5e-77 260.7 27.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH37340.1 - 2.2e-17 63.0 39.0 2.7e-15 56.2 36.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KXH37340.1 - 0.0021 17.0 3.7 0.0021 17.0 3.7 2.2 2 1 0 2 2 2 1 MFS_1 like family YtpI PF14007.6 KXH37340.1 - 1.5 9.1 12.4 2.7 8.2 4.3 3.0 3 0 0 3 3 3 0 YtpI-like protein Fungal_trans_2 PF11951.8 KXH37341.1 - 5.7e-30 104.4 3.9 8.3e-30 103.8 3.9 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain DIOX_N PF14226.6 KXH37342.1 - 2.7e-21 76.5 0.0 4.7e-21 75.7 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KXH37342.1 - 1.8e-13 50.8 0.0 3.1e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CvfB_WH PF17783.1 KXH37342.1 - 0.09 12.6 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 CvfB-like winged helix domain AltA1 PF16541.5 KXH37343.1 - 5.7e-07 30.4 0.0 8.1e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 Alternaria alternata allergen 1 Glyco_hydro_43 PF04616.14 KXH37344.1 - 7.2e-22 78.0 11.8 1.7e-10 40.7 0.2 3.3 3 1 0 3 3 3 3 Glycosyl hydrolases family 43 GFO_IDH_MocA PF01408.22 KXH37345.1 - 1.7e-24 86.9 0.2 2.5e-24 86.4 0.2 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KXH37345.1 - 2e-15 56.8 0.0 3.5e-15 56.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Semialdhyde_dh PF01118.24 KXH37345.1 - 0.0023 18.3 0.1 0.0046 17.4 0.1 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Gp_dh_N PF00044.24 KXH37345.1 - 0.073 13.4 0.0 0.37 11.2 0.0 2.0 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain HD_3 PF13023.6 KXH37346.1 - 3.8e-50 170.0 0.0 4.8e-50 169.7 0.0 1.1 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 KXH37346.1 - 3.4e-09 36.7 0.0 5e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 KXH37346.1 - 0.1 12.8 0.1 0.28 11.4 0.0 1.8 1 1 1 2 2 2 0 HD domain MFS_1 PF07690.16 KXH37349.1 - 3.1e-42 144.8 42.0 3.1e-42 144.8 42.0 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH37349.1 - 1.3e-10 40.7 36.1 2.7e-07 29.8 11.1 3.7 3 1 0 3 3 3 2 Sugar (and other) transporter Nuc_sug_transp PF04142.15 KXH37352.1 - 2.6e-48 164.8 1.3 3.4e-48 164.4 1.3 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.11 KXH37352.1 - 3.8e-06 26.3 1.0 3.8e-06 26.3 1.0 1.7 2 0 0 2 2 2 1 UAA transporter family PUNUT PF16913.5 KXH37352.1 - 0.00046 19.5 1.8 0.0007 18.9 1.8 1.4 1 1 0 1 1 1 1 Purine nucleobase transmembrane transport CRT-like PF08627.10 KXH37352.1 - 0.0011 18.0 0.4 0.0017 17.3 0.4 1.2 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 KXH37352.1 - 0.0084 16.3 1.5 0.0084 16.3 1.5 2.8 2 1 0 2 2 2 1 EamA-like transporter family Phage_holin_5_1 PF06946.11 KXH37352.1 - 0.083 13.3 0.1 0.21 12.0 0.1 1.8 1 0 0 1 1 1 0 Bacteriophage A118-like holin, Hol118 MerC PF03203.14 KXH37352.1 - 1.4 9.4 10.4 12 6.4 9.5 2.6 1 1 0 1 1 1 0 MerC mercury resistance protein PWI PF01480.17 KXH37353.1 - 3.2e-15 56.2 0.5 7.7e-15 55.0 0.5 1.7 1 0 0 1 1 1 1 PWI domain Ribosomal_S21 PF01165.20 KXH37354.1 - 4.8e-14 51.8 4.4 7.2e-14 51.2 4.4 1.3 1 0 0 1 1 1 1 Ribosomal protein S21 HAUS6_N PF14661.6 KXH37355.1 - 1.5e-57 194.8 3.7 3e-57 193.8 3.7 1.5 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 6 N-terminus TTL PF03133.15 KXH37357.1 - 1.8e-33 116.0 0.0 6.7e-33 114.1 0.0 1.8 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 KXH37357.1 - 0.00046 19.5 0.0 0.001 18.4 0.0 1.5 1 0 0 1 1 1 1 YheC/D like ATP-grasp Dala_Dala_lig_C PF07478.13 KXH37357.1 - 0.0095 15.5 0.0 0.023 14.3 0.0 1.6 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Glycos_transf_2 PF00535.26 KXH37357.1 - 0.14 12.0 0.0 1.3 8.8 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferase family 2 Glyco_hydro_76 PF03663.14 KXH37486.1 - 6.9e-157 522.7 15.4 8e-157 522.4 15.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 KXH37486.1 - 0.00014 21.1 6.4 0.099 11.7 0.1 3.0 3 0 0 3 3 3 2 Glycosyl Hydrolase Family 88 Dak1 PF02733.17 KXH37487.1 - 3.3e-104 348.1 6.4 4.4e-104 347.7 6.4 1.2 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 KXH37487.1 - 1.7e-47 161.5 0.8 1.7e-47 161.5 0.8 1.9 2 0 0 2 2 2 1 DAK2 domain LSM PF01423.22 KXH37488.1 - 6.5e-18 64.2 0.1 9.1e-18 63.7 0.1 1.2 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 KXH37488.1 - 0.12 12.0 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Hfq protein Syndecan PF01034.20 KXH37492.1 - 0.0036 17.2 0.0 0.0074 16.2 0.0 1.4 1 0 0 1 1 1 1 Syndecan domain Podoplanin PF05808.11 KXH37492.1 - 0.042 14.0 2.4 0.082 13.0 2.4 1.4 1 0 0 1 1 1 0 Podoplanin SKG6 PF08693.10 KXH37492.1 - 0.16 11.4 4.2 0.33 10.4 4.2 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Na_Ca_ex PF01699.24 KXH37492.1 - 1.8 8.5 5.8 0.56 10.2 0.7 2.1 2 0 0 2 2 2 0 Sodium/calcium exchanger protein FMN_dh PF01070.18 KXH37493.1 - 3.5e-114 381.5 0.0 4.2e-114 381.2 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 KXH37493.1 - 3e-18 65.7 0.0 5.7e-18 64.8 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain IMPDH PF00478.25 KXH37493.1 - 8e-05 21.8 0.8 0.00061 18.9 0.4 2.4 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 KXH37493.1 - 0.00011 21.5 0.0 0.00018 20.8 0.0 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.15 KXH37493.1 - 0.00083 18.8 0.3 0.0015 18.0 0.1 1.4 1 1 0 1 1 1 1 Nitronate monooxygenase DUF4202 PF13875.6 KXH37494.1 - 4.2e-76 255.0 0.4 4.7e-76 254.8 0.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4202) Myb_DNA-bind_6 PF13921.6 KXH37495.1 - 6.1e-05 23.2 0.0 0.00018 21.7 0.0 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KXH37495.1 - 0.00071 19.7 0.3 0.0015 18.7 0.3 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain 14-3-3 PF00244.20 KXH37496.1 - 1.4e-08 34.6 0.0 7.1e-08 32.2 0.0 1.8 2 0 0 2 2 2 1 14-3-3 protein Sterol-sensing PF12349.8 KXH37497.1 - 5e-37 127.1 9.9 8.8e-37 126.3 9.9 1.4 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 KXH37497.1 - 3.1e-11 42.2 5.1 4.5e-11 41.6 5.1 1.1 1 0 0 1 1 1 1 Patched family WD40 PF00400.32 KXH37497.1 - 0.0031 18.3 0.2 2.1 9.4 0.0 3.3 2 0 0 2 2 2 2 WD domain, G-beta repeat MMPL PF03176.15 KXH37497.1 - 0.021 13.7 0.1 0.021 13.7 0.1 1.7 2 0 0 2 2 2 0 MMPL family Cupin_8 PF13621.6 KXH37498.1 - 6.1e-70 235.8 0.1 7.1e-70 235.6 0.1 1.0 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 KXH37498.1 - 7.9e-07 28.8 0.0 0.00031 20.3 0.0 2.3 2 0 0 2 2 2 2 Cupin superfamily protein JmjC PF02373.22 KXH37498.1 - 0.11 12.9 0.1 1.2 9.6 0.0 2.5 3 0 0 3 3 3 0 JmjC domain, hydroxylase N-SET PF11764.8 KXH37499.1 - 1.5e-45 155.4 0.6 1.5e-45 155.4 0.6 2.7 2 0 0 2 2 2 1 COMPASS (Complex proteins associated with Set1p) component N SET_assoc PF11767.8 KXH37499.1 - 6.4e-26 89.8 2.6 7.5e-26 89.6 0.3 2.4 3 0 0 3 3 3 1 Histone lysine methyltransferase SET associated SET PF00856.28 KXH37499.1 - 2.8e-13 50.6 7.5 6.8e-13 49.3 0.1 4.1 3 2 0 3 3 3 1 SET domain RRM_1 PF00076.22 KXH37499.1 - 0.014 15.2 0.2 2.4 8.1 0.0 2.8 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 KXH37499.1 - 0.08 13.0 0.1 20 5.4 0.1 2.7 2 0 0 2 2 2 0 Limkain b1 Tropomyosin_1 PF12718.7 KXH37501.1 - 3.4e-53 179.6 29.7 4e-53 179.4 29.7 1.0 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.20 KXH37501.1 - 3.9e-08 33.0 30.1 0.00013 21.4 11.9 3.0 1 1 2 3 3 3 3 Tropomyosin CENP-F_leu_zip PF10473.9 KXH37501.1 - 0.00017 21.7 3.9 0.00017 21.7 3.9 2.9 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF724 PF05266.14 KXH37501.1 - 0.00046 20.1 22.5 0.018 14.9 8.2 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF724) Spc7 PF08317.11 KXH37501.1 - 0.00046 19.2 30.6 0.0085 15.0 12.3 2.0 1 1 1 2 2 2 2 Spc7 kinetochore protein Lebercilin PF15619.6 KXH37501.1 - 0.00063 19.5 28.5 0.1 12.3 14.6 2.1 1 1 1 2 2 2 2 Ciliary protein causing Leber congenital amaurosis disease DUF4200 PF13863.6 KXH37501.1 - 0.00078 19.8 31.4 0.092 13.2 9.2 2.4 2 1 0 2 2 2 2 Domain of unknown function (DUF4200) ATG16 PF08614.11 KXH37501.1 - 0.0012 19.1 29.3 0.14 12.4 12.8 2.2 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) ADIP PF11559.8 KXH37501.1 - 0.0013 18.8 27.5 0.0034 17.5 6.8 3.1 1 1 2 3 3 3 1 Afadin- and alpha -actinin-Binding Taxilin PF09728.9 KXH37501.1 - 0.0014 17.8 26.5 0.21 10.7 13.3 2.1 1 1 1 2 2 2 2 Myosin-like coiled-coil protein Uso1_p115_C PF04871.13 KXH37501.1 - 0.0015 18.9 32.1 0.053 13.9 13.1 2.0 1 1 1 2 2 2 2 Uso1 / p115 like vesicle tethering protein, C terminal region TACC_C PF05010.14 KXH37501.1 - 0.002 18.0 21.3 0.0098 15.7 11.3 2.3 1 1 1 2 2 2 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal HOOK PF05622.12 KXH37501.1 - 0.0041 15.4 23.5 0.0054 14.9 23.5 1.2 1 0 0 1 1 1 1 HOOK protein TMF_TATA_bd PF12325.8 KXH37501.1 - 0.0044 17.2 21.9 0.051 13.8 13.5 2.4 1 1 1 2 2 2 1 TATA element modulatory factor 1 TATA binding GAS PF13851.6 KXH37501.1 - 0.0071 15.7 28.7 0.56 9.5 5.5 2.1 1 1 0 1 1 1 1 Growth-arrest specific micro-tubule binding Surfac_D-trimer PF09006.11 KXH37501.1 - 0.0088 15.9 0.9 0.044 13.7 0.0 2.5 3 0 0 3 3 1 1 Lung surfactant protein D coiled-coil trimerisation FlaC_arch PF05377.11 KXH37501.1 - 0.012 15.9 18.0 0.24 11.8 4.2 4.4 3 2 1 4 4 4 0 Flagella accessory protein C (FlaC) KLRAQ PF10205.9 KXH37501.1 - 0.014 15.6 20.5 0.036 14.3 6.5 3.0 1 1 2 3 3 3 0 Predicted coiled-coil domain-containing protein Fez1 PF06818.15 KXH37501.1 - 0.017 15.6 24.0 0.031 14.7 23.9 1.4 1 1 0 1 1 1 0 Fez1 ERM PF00769.19 KXH37501.1 - 0.019 14.8 33.3 0.038 13.8 15.6 2.0 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Cast PF10174.9 KXH37501.1 - 0.019 13.2 20.9 0.024 12.9 20.9 1.1 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone HMMR_C PF15908.5 KXH37501.1 - 0.02 15.1 4.1 0.02 15.1 4.1 2.5 1 1 0 2 2 2 0 Hyaluronan mediated motility receptor C-terminal Syntaxin_2 PF14523.6 KXH37501.1 - 0.021 15.2 3.8 0.021 15.2 3.8 2.2 2 0 0 2 2 2 0 Syntaxin-like protein T3SSipB PF16535.5 KXH37501.1 - 0.037 14.5 18.6 1 9.8 9.1 2.5 1 1 1 2 2 2 0 Type III cell invasion protein SipB DUF3450 PF11932.8 KXH37501.1 - 0.038 13.3 24.9 0.44 9.8 11.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF1664 PF07889.12 KXH37501.1 - 0.052 13.6 13.6 0.28 11.2 3.2 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) TPR_MLP1_2 PF07926.12 KXH37501.1 - 0.053 13.6 32.6 0.17 12.0 9.1 2.5 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein bZIP_1 PF00170.21 KXH37501.1 - 0.055 13.6 30.0 0.23 11.6 3.7 4.8 3 2 2 5 5 4 0 bZIP transcription factor DUF4763 PF15960.5 KXH37501.1 - 0.061 12.6 15.7 0.17 11.2 3.5 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4763) CENP-K PF11802.8 KXH37501.1 - 0.062 12.9 16.6 0.53 9.8 4.7 2.0 1 1 1 2 2 2 0 Centromere-associated protein K APG6_N PF17675.1 KXH37501.1 - 0.062 13.8 36.0 1.3 9.5 11.2 2.3 1 1 1 2 2 2 0 Apg6 coiled-coil region EzrA PF06160.12 KXH37501.1 - 0.063 11.4 21.2 0.066 11.4 6.1 2.0 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA Syntaxin-6_N PF09177.11 KXH37501.1 - 0.064 13.8 15.8 1.3 9.6 6.1 2.7 1 1 1 2 2 2 0 Syntaxin 6, N-terminal KASH_CCD PF14662.6 KXH37501.1 - 0.076 12.8 28.4 0.063 13.1 25.6 2.5 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Fmp27_WPPW PF10359.9 KXH37501.1 - 0.081 11.8 22.2 0.031 13.1 8.3 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain Cortex-I_coil PF09304.10 KXH37501.1 - 0.082 13.1 21.6 5 7.4 5.9 3.3 1 1 2 3 3 3 0 Cortexillin I, coiled coil DUF3287 PF11690.8 KXH37501.1 - 0.086 12.6 4.2 0.66 9.7 0.3 2.8 1 1 1 3 3 3 0 Protein of unknown function (DUF3287) CASP_C PF08172.12 KXH37501.1 - 0.091 12.1 19.7 0.12 11.7 2.7 2.1 1 1 1 2 2 2 0 CASP C terminal UPF0242 PF06785.11 KXH37501.1 - 0.093 12.8 29.4 0.14 12.2 9.3 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Laminin_II PF06009.12 KXH37501.1 - 0.095 12.7 16.5 0.02 14.9 4.5 2.5 1 1 1 2 2 2 0 Laminin Domain II Jnk-SapK_ap_N PF09744.9 KXH37501.1 - 0.098 12.9 29.5 0.073 13.3 16.5 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 DUF5082 PF16888.5 KXH37501.1 - 0.11 12.8 19.6 1.7 8.9 6.2 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF5082) NPV_P10 PF05531.12 KXH37501.1 - 0.12 12.9 8.0 1.6 9.3 2.2 3.2 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein Filament PF00038.21 KXH37501.1 - 0.13 11.8 23.8 0.47 10.0 23.8 1.8 1 1 0 1 1 1 0 Intermediate filament protein DUF2203 PF09969.9 KXH37501.1 - 0.13 12.9 16.3 0.98 10.2 4.4 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) MAD PF05557.13 KXH37501.1 - 0.14 10.5 23.5 0.13 10.6 11.3 2.0 1 1 1 2 2 2 0 Mitotic checkpoint protein CLZ PF16526.5 KXH37501.1 - 0.14 12.5 23.7 0.75 10.2 1.7 3.7 1 1 2 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels SOGA PF11365.8 KXH37501.1 - 0.16 13.1 22.4 1.9 9.7 9.7 3.4 1 1 2 3 3 3 0 Protein SOGA Rab5-bind PF09311.11 KXH37501.1 - 0.19 11.1 22.7 0.79 9.1 8.5 2.0 2 0 0 2 2 2 0 Rabaptin-like protein Cep57_CLD_2 PF14197.6 KXH37501.1 - 0.2 11.7 24.7 1.7 8.8 3.7 4.2 2 2 0 2 2 2 0 Centrosome localisation domain of PPC89 KELK PF15796.5 KXH37501.1 - 0.26 11.8 30.1 0.3 11.6 3.3 3.7 1 1 3 4 4 4 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase HAP1_N PF04849.13 KXH37501.1 - 0.29 10.3 26.3 0.61 9.2 26.3 1.9 1 1 0 1 1 1 0 HAP1 N-terminal conserved region CALCOCO1 PF07888.11 KXH37501.1 - 0.31 9.9 27.6 1.8 7.3 9.6 2.0 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like LPP PF04728.13 KXH37501.1 - 0.36 11.2 10.9 15 6.1 0.1 4.2 3 1 0 3 3 3 0 Lipoprotein leucine-zipper Seryl_tRNA_N PF02403.22 KXH37501.1 - 0.51 10.6 24.1 0.72 10.1 0.3 3.1 1 1 1 2 2 1 0 Seryl-tRNA synthetase N-terminal domain VGPC1_C PF16799.5 KXH37501.1 - 0.51 10.3 8.8 0.46 10.5 3.8 2.9 2 1 0 2 2 2 0 C-terminal membrane-localisation domain of ion-channel, VCN1 Sec34 PF04136.15 KXH37501.1 - 0.65 9.9 14.0 0.23 11.3 2.9 2.3 2 0 0 2 2 2 0 Sec34-like family Alanine_zipper PF11839.8 KXH37501.1 - 0.75 10.2 11.3 1.5 9.3 2.1 3.8 1 1 2 3 3 3 0 Alanine-zipper, major outer membrane lipoprotein TANGO2 PF05742.12 KXH37501.1 - 0.81 9.7 6.6 1.4 8.9 6.6 1.5 1 1 0 1 1 1 0 Transport and Golgi organisation 2 PI3K_P85_iSH2 PF16454.5 KXH37501.1 - 0.98 9.0 21.1 3.7 7.1 21.2 1.9 1 1 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain TMF_DNA_bd PF12329.8 KXH37501.1 - 1.3 9.1 32.2 0.75 9.8 12.7 3.0 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding Lectin_N PF03954.14 KXH37501.1 - 1.5 8.6 14.4 0.84 9.4 3.6 2.6 1 1 2 3 3 3 0 Hepatic lectin, N-terminal domain DUF3584 PF12128.8 KXH37501.1 - 1.5 6.2 23.6 2.2 5.7 23.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) BRE1 PF08647.11 KXH37501.1 - 1.6 8.8 28.7 21 5.3 4.3 3.0 1 1 2 3 3 3 0 BRE1 E3 ubiquitin ligase DUF4407 PF14362.6 KXH37501.1 - 1.6 8.0 20.9 3.8 6.8 20.9 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2730 PF10805.8 KXH37501.1 - 1.8 8.7 12.7 0.55 10.3 2.9 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) AAA_13 PF13166.6 KXH37501.1 - 1.9 7.0 22.2 0.27 9.8 7.0 2.0 1 1 0 2 2 2 0 AAA domain FUSC PF04632.12 KXH37501.1 - 2.1 6.7 5.8 2.3 6.6 5.8 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family XhlA PF10779.9 KXH37501.1 - 2.2 8.6 21.7 3.5 7.9 1.9 4.1 2 1 3 5 5 5 0 Haemolysin XhlA DUF4686 PF15742.5 KXH37501.1 - 2.2 7.3 28.6 1.3 8.1 9.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4686) CHDCT2 PF08074.11 KXH37501.1 - 2.3 8.4 9.1 0.26 11.4 3.0 2.0 1 1 1 2 2 2 0 CHDCT2 (NUC038) domain WXG100 PF06013.12 KXH37501.1 - 2.4 8.4 15.3 7.5 6.9 0.2 4.1 3 1 1 4 4 4 0 Proteins of 100 residues with WXG Atg14 PF10186.9 KXH37501.1 - 2.6 7.0 19.6 2 7.4 10.1 2.0 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF2937 PF11157.8 KXH37501.1 - 2.9 7.6 9.0 2.3 7.9 5.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2937) Methyltransf_9 PF08003.11 KXH37501.1 - 3 6.7 6.8 4.5 6.1 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) Fib_alpha PF08702.10 KXH37501.1 - 3.5 7.8 15.5 5.3 7.2 3.4 2.4 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Rootletin PF15035.6 KXH37501.1 - 3.5 7.6 26.7 72 3.3 26.8 2.1 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DHR10 PF18595.1 KXH37501.1 - 3.6 7.7 32.3 25 5.0 23.2 3.0 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain DUF4482 PF14818.6 KXH37501.1 - 4 8.3 20.8 0.25 12.2 2.0 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4482) DUF745 PF05335.13 KXH37501.1 - 4 7.1 18.9 0.19 11.4 5.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF745) TRAF_BIRC3_bd PF16673.5 KXH37501.1 - 4.4 7.2 16.3 5.2 6.9 1.4 4.1 2 2 3 5 5 5 0 TNF receptor-associated factor BIRC3 binding domain CENP-H PF05837.12 KXH37501.1 - 4.6 7.7 23.7 12 6.3 0.2 3.0 1 1 2 3 3 3 0 Centromere protein H (CENP-H) CENP-Q PF13094.6 KXH37501.1 - 4.9 7.3 30.0 24 5.1 16.5 3.4 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit FAM76 PF16046.5 KXH37501.1 - 5.2 6.3 20.6 3.6 6.9 10.6 2.0 1 1 1 2 2 2 0 FAM76 protein ZapB PF06005.12 KXH37501.1 - 5.5 7.5 36.2 12 6.4 0.6 4.1 1 1 2 3 3 3 0 Cell division protein ZapB HAUS-augmin3 PF14932.6 KXH37501.1 - 5.6 6.5 26.6 2.7 7.5 11.5 2.5 1 1 2 3 3 3 0 HAUS augmin-like complex subunit 3 CorA PF01544.18 KXH37501.1 - 6.2 6.0 8.3 6.8 5.9 7.4 1.5 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein Cep57_MT_bd PF06657.13 KXH37501.1 - 6.4 7.3 18.7 1.2 9.7 2.5 3.4 1 1 1 3 3 3 0 Centrosome microtubule-binding domain of Cep57 YabA PF06156.13 KXH37501.1 - 6.5 7.4 21.6 62 4.3 0.4 3.1 1 1 1 2 2 1 0 Initiation control protein YabA BST2 PF16716.5 KXH37501.1 - 7.8 7.2 25.3 7.3 7.3 8.8 3.5 1 1 2 3 3 3 0 Bone marrow stromal antigen 2 OmpH PF03938.14 KXH37501.1 - 8.4 6.7 32.1 7.5 6.9 17.4 2.6 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) SlyX PF04102.12 KXH37501.1 - 8.5 7.1 21.1 0.79 10.4 1.8 3.8 1 1 4 5 5 5 0 SlyX DUF812 PF05667.11 KXH37501.1 - 8.7 5.1 26.0 17 4.1 26.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF812) KxDL PF10241.9 KXH37501.1 - 9 6.6 15.0 2.1 8.7 2.2 3.5 1 1 3 4 4 4 0 Uncharacterized conserved protein Nop25 PF09805.9 KXH37502.1 - 1.7e-39 135.4 14.1 1.7e-39 135.4 14.1 2.6 2 1 0 2 2 2 1 Nucleolar protein 12 (25kDa) EIIBC-GUT_N PF03612.14 KXH37502.1 - 1.7 8.4 13.3 0.16 11.7 3.9 2.2 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus ATP-synt_S1 PF05827.12 KXH37503.1 - 0.0038 17.0 0.0 0.0073 16.1 0.0 1.4 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) Trm112p PF03966.16 KXH37504.1 - 1.5e-18 67.1 0.1 1.9e-18 66.8 0.1 1.1 1 0 0 1 1 1 1 Trm112p-like protein Zn_ribbon_recom PF13408.6 KXH37504.1 - 0.07 13.7 0.3 0.11 13.0 0.3 1.3 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain Pro_isomerase PF00160.21 KXH37505.1 - 9e-50 169.0 0.4 1.2e-49 168.6 0.4 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ribosomal_S13 PF00416.22 KXH37506.1 - 8.7e-15 55.2 0.1 2e-12 47.6 0.1 2.0 1 1 0 1 1 1 1 Ribosomal protein S13/S18 Peptidase_M19 PF01244.21 KXH37507.1 - 2.1e-102 342.5 0.0 2.5e-102 342.3 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Amidohydro_2 PF04909.14 KXH37507.1 - 0.06 13.1 0.0 0.11 12.2 0.0 1.4 1 1 0 1 1 1 0 Amidohydrolase RhoGAP PF00620.27 KXH37508.1 - 2.4e-16 59.9 0.0 5.3e-16 58.8 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain DEP PF00610.21 KXH37508.1 - 2.7e-13 49.8 0.0 5.8e-13 48.7 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) FCH PF00611.23 KXH37508.1 - 1.3e-11 44.6 0.0 4.3e-11 42.9 0.0 2.0 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain BAR PF03114.18 KXH37508.1 - 0.029 14.0 0.8 0.083 12.5 0.8 1.7 1 0 0 1 1 1 0 BAR domain DUF2951 PF11166.8 KXH37508.1 - 0.038 14.2 0.6 0.32 11.2 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) DUF5476 PF17570.2 KXH37508.1 - 1.3 9.5 3.5 7.5 7.0 1.6 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5476) Adaptin_N PF01602.20 KXH37509.1 - 2.7e-73 247.3 0.0 4.3e-73 246.7 0.0 1.3 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KXH37509.1 - 0.00017 21.7 0.0 0.0095 16.0 0.0 2.4 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KXH37509.1 - 0.054 13.9 0.0 0.38 11.2 0.0 2.5 1 1 0 1 1 1 0 HEAT repeats RNA_polI_A34 PF08208.11 KXH37509.1 - 3.8 7.6 13.8 6.3 6.8 11.3 2.2 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 NDT80_PhoG PF05224.12 KXH37573.1 - 9.6e-42 143.3 0.0 1.5e-41 142.7 0.0 1.3 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family AMP-binding PF00501.28 KXH37582.1 - 8.2e-38 130.1 0.0 9.9e-38 129.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Gly_transf_sug PF04488.15 KXH37583.1 - 2.7e-14 53.6 0.0 5.8e-14 52.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Cu_amine_oxid PF01179.20 KXH37584.1 - 7.4e-153 509.3 0.0 9.1e-153 509.0 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.16 KXH37584.1 - 2.2e-05 24.6 0.1 6.4e-05 23.1 0.0 1.8 2 0 0 2 2 2 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.16 KXH37584.1 - 0.00017 21.9 0.0 0.00036 20.9 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain DLIC PF05783.11 KXH37586.1 - 4.9e-26 91.6 0.2 2.9e-25 89.1 0.0 2.3 2 2 0 2 2 2 1 Dynein light intermediate chain (DLIC) RRM_1 PF00076.22 KXH37587.1 - 4.8e-15 55.1 0.0 5.6e-14 51.7 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KXH37587.1 - 0.0027 17.8 0.0 0.0063 16.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif WD40 PF00400.32 KXH37588.1 - 0.00028 21.6 0.2 1.9 9.5 0.0 3.5 3 0 0 3 3 3 2 WD domain, G-beta repeat Nbas_N PF15492.6 KXH37588.1 - 0.037 13.3 0.0 0.076 12.3 0.0 1.5 1 0 0 1 1 1 0 Neuroblastoma-amplified sequence, N terminal Septin PF00735.18 KXH37589.1 - 4.9e-107 357.4 0.0 1.1e-106 356.3 0.0 1.5 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 KXH37589.1 - 0.00013 22.0 0.0 0.00032 20.8 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 KXH37589.1 - 0.008 16.3 4.9 1.4 8.9 0.0 3.1 2 1 1 3 3 3 2 Dynamin family AAA_23 PF13476.6 KXH37589.1 - 0.017 15.6 3.7 4.6 7.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain IIGP PF05049.13 KXH37589.1 - 0.027 13.6 0.0 0.052 12.6 0.0 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) EB1 PF03271.17 KXH37589.1 - 0.037 14.3 1.2 1.8 8.9 1.3 2.6 2 0 0 2 2 2 0 EB1-like C-terminal motif GTP_EFTU PF00009.27 KXH37589.1 - 0.26 10.8 0.8 1.1 8.8 0.0 2.2 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KXH37589.1 - 0.32 10.9 5.4 0.13 12.1 1.1 2.5 2 1 0 2 2 2 0 RsgA GTPase AAA_22 PF13401.6 KXH37589.1 - 0.4 10.9 1.7 0.53 10.6 0.2 2.0 2 1 0 2 2 2 0 AAA domain Bax1-I PF01027.20 KXH37590.1 - 5e-52 176.7 28.5 5.8e-52 176.5 28.5 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Spore_YhaL PF14147.6 KXH37590.1 - 0.12 12.1 0.6 0.7 9.6 0.1 2.6 2 0 0 2 2 2 0 Sporulation protein YhaL TRAM_LAG1_CLN8 PF03798.16 KXH37591.1 - 4.1e-46 157.2 17.4 4.1e-46 157.2 17.4 1.6 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 KXH37591.1 - 1.6e-22 78.9 0.3 9.7e-22 76.4 0.0 2.5 2 0 0 2 2 2 1 TRAM1-like protein TMEM154 PF15102.6 KXH37591.1 - 0.075 12.9 0.3 0.2 11.6 0.0 1.7 2 0 0 2 2 2 0 TMEM154 protein family Thioredox_DsbH PF03190.15 KXH37592.1 - 2e-57 193.7 0.0 3.1e-57 193.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.6 KXH37592.1 - 0.0019 18.3 0.0 0.0042 17.2 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like GlcNAc_2-epim PF07221.11 KXH37592.1 - 0.0049 16.2 0.1 0.0092 15.3 0.1 1.3 1 0 0 1 1 1 1 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) Glyco_hydro_76 PF03663.14 KXH37592.1 - 0.0094 15.5 0.5 0.032 13.7 0.1 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 76 Histone_HNS PF00816.21 KXH37592.1 - 0.098 13.5 0.2 8.7 7.2 0.1 2.7 2 0 0 2 2 2 0 H-NS histone family SSF PF00474.17 KXH37593.1 - 1.5e-24 86.6 29.9 2.2e-24 86.1 29.9 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family DUF3087 PF11286.8 KXH37593.1 - 4.9 6.6 6.5 0.47 9.9 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3087) CAP PF00188.26 KXH37594.1 - 6.2e-21 75.5 2.7 8.6e-21 75.1 2.7 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Med13_C PF06333.12 KXH37594.1 - 0.059 12.6 9.3 0.079 12.2 9.3 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain CHCH PF06747.13 KXH37595.1 - 4.2e-07 29.9 13.2 1.8e-05 24.7 3.3 2.6 3 0 0 3 3 3 2 CHCH domain CX9C PF16860.5 KXH37595.1 - 5.6e-05 23.1 6.1 0.0032 17.4 3.3 2.2 2 0 0 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Cmc1 PF08583.10 KXH37595.1 - 0.0083 16.1 10.4 0.11 12.6 0.7 2.2 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.9 KXH37595.1 - 0.17 12.2 9.5 0.98 9.8 1.1 2.8 1 1 2 3 3 3 0 Cytochrome c oxidase assembly protein PET191 Nup54 PF13874.6 KXH37596.1 - 6.1e-39 133.3 1.7 1.1e-38 132.5 0.2 1.9 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 Nup54_57_C PF18570.1 KXH37596.1 - 5.1e-16 57.9 10.8 1.1e-15 56.9 7.5 2.3 2 0 0 2 2 2 1 NUP57/Nup54 C-terminal domain DivIVA PF05103.13 KXH37596.1 - 0.0016 18.6 1.3 0.0016 18.6 1.3 1.7 2 0 0 2 2 2 1 DivIVA protein Adhesin_P1_N PF18652.1 KXH37596.1 - 0.0027 17.7 0.8 0.0069 16.4 0.8 1.6 1 0 0 1 1 1 1 Adhesin P1 N-terminal domain DUF948 PF06103.11 KXH37596.1 - 0.038 14.2 0.7 2 8.7 0.1 2.7 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) YliH PF10799.8 KXH37596.1 - 0.041 13.8 0.3 0.1 12.5 0.1 1.7 1 1 0 1 1 1 0 Biofilm formation protein (YliH/bssR) Cnn_1N PF07989.11 KXH37596.1 - 0.059 13.5 5.1 6.1 7.1 1.3 2.8 3 0 0 3 3 3 0 Centrosomin N-terminal motif 1 ABC_tran_CTD PF16326.5 KXH37596.1 - 0.066 13.5 6.1 2 8.7 1.1 3.3 3 0 0 3 3 3 0 ABC transporter C-terminal domain V-SNARE_C PF12352.8 KXH37596.1 - 0.069 13.5 0.4 1.4 9.2 0.1 2.3 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus DUF4337 PF14235.6 KXH37596.1 - 0.096 12.8 1.6 0.15 12.1 1.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) HTH_39 PF14090.6 KXH37596.1 - 0.1 12.4 0.1 0.18 11.6 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain FlaC_arch PF05377.11 KXH37596.1 - 0.31 11.5 1.8 4.6 7.7 0.3 2.8 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Prefoldin_2 PF01920.20 KXH37596.1 - 4.7 7.2 8.7 2 8.4 4.6 2.4 2 1 0 2 2 2 0 Prefoldin subunit Tom5 PF10642.9 KXH37597.1 - 2.4e-23 81.9 0.6 2.6e-23 81.8 0.6 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit or translocase GDC-P PF02347.16 KXH37598.1 - 7.9e-171 568.6 0.0 3.1e-161 537.0 0.0 2.9 2 1 0 2 2 2 2 Glycine cleavage system P-protein Aminotran_5 PF00266.19 KXH37598.1 - 4.9e-10 38.9 0.0 0.00079 18.5 0.0 2.2 2 0 0 2 2 2 2 Aminotransferase class-V Beta_elim_lyase PF01212.21 KXH37598.1 - 5.9e-05 22.5 0.0 0.00011 21.7 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 KXH37598.1 - 0.003 16.2 0.0 0.0066 15.0 0.0 1.5 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme B12-binding PF02310.19 KXH37598.1 - 0.028 14.4 0.5 0.15 12.1 0.1 2.4 3 0 0 3 3 3 0 B12 binding domain Ras PF00071.22 KXH37617.1 - 1.3e-54 184.2 0.0 1.5e-54 183.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXH37617.1 - 1.7e-21 76.6 0.0 3.3e-21 75.7 0.0 1.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXH37617.1 - 1.2e-09 37.8 0.0 1.9e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KXH37617.1 - 0.00039 19.8 0.0 0.00051 19.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 KXH37617.1 - 0.0018 17.5 0.0 0.002 17.3 0.0 1.2 1 0 0 1 1 1 1 G-protein alpha subunit MMR_HSR1 PF01926.23 KXH37617.1 - 0.0051 16.9 0.0 0.011 15.8 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 KXH37617.1 - 0.0086 15.5 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit ABC_tran PF00005.27 KXH37617.1 - 0.097 13.2 0.0 0.13 12.8 0.0 1.5 1 1 0 1 1 1 0 ABC transporter EBP50_C PF09007.11 KXH37618.1 - 0.45 11.5 4.8 0.15 13.1 0.9 2.0 1 1 1 2 2 2 0 EBP50, C-terminal DUF1275 PF06912.11 KXH37619.1 - 1.2e-49 168.9 5.1 1.6e-49 168.4 5.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) MFS_1 PF07690.16 KXH37619.1 - 0.00087 18.3 8.0 0.014 14.4 2.3 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF4131 PF13567.6 KXH37619.1 - 0.0095 15.6 3.3 1 9.0 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4131) Glyco_hydro_16 PF00722.21 KXH37620.1 - 2.9e-38 131.1 1.8 5.6e-38 130.2 1.8 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Fungal_trans_2 PF11951.8 KXH37622.1 - 2.9e-38 131.7 0.0 1.1e-24 87.0 0.1 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH37622.1 - 1.2e-07 31.8 5.2 2.2e-07 30.9 5.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HisKA_3 PF07730.13 KXH37622.1 - 1.5 9.4 4.6 79 3.9 0.0 3.6 4 0 0 4 4 4 0 Histidine kinase ADH_N PF08240.12 KXH37623.1 - 1.5e-25 89.2 3.5 3.1e-25 88.2 3.5 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXH37623.1 - 6.9e-16 58.4 0.1 1.2e-15 57.7 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KXH37623.1 - 0.00011 21.7 0.4 0.0016 18.0 0.3 2.1 2 0 0 2 2 2 1 Glucose dehydrogenase C-terminus TrkA_N PF02254.18 KXH37623.1 - 0.099 12.9 0.2 0.27 11.5 0.1 1.8 2 0 0 2 2 2 0 TrkA-N domain adh_short_C2 PF13561.6 KXH37624.1 - 7.7e-47 159.8 0.1 8.7e-47 159.6 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXH37624.1 - 2.6e-37 128.2 0.1 3.5e-37 127.8 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXH37624.1 - 9.4e-07 28.9 0.0 1.3e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXH37624.1 - 0.019 14.5 0.1 0.055 12.9 0.1 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF4246 PF14033.6 KXH37625.1 - 2.5e-160 534.5 0.0 3.9e-160 533.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_5 PF13759.6 KXH37625.1 - 0.022 15.1 0.0 0.058 13.8 0.0 1.6 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase Sugar_tr PF00083.24 KXH37626.1 - 7e-76 255.9 14.7 1.2e-75 255.1 14.7 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH37626.1 - 7.8e-17 61.2 29.8 8.2e-09 34.8 14.1 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Aminotran_1_2 PF00155.21 KXH37627.1 - 9e-37 127.1 0.0 1.1e-36 126.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KXH37627.1 - 1.8e-07 30.5 0.0 4.3e-07 29.2 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 KXH37627.1 - 0.00013 20.7 0.0 0.00019 20.1 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 KXH37627.1 - 0.0018 17.6 0.0 0.0025 17.2 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Alliinase_C PF04864.13 KXH37627.1 - 0.049 12.5 0.1 0.087 11.7 0.1 1.5 1 1 0 1 1 1 0 Allinase RNase_Zc3h12a PF11977.8 KXH37627.1 - 0.1 12.4 0.0 3.6 7.3 0.0 2.2 2 0 0 2 2 2 0 Zc3h12a-like Ribonuclease NYN domain CPSase_L_D2 PF02786.17 KXH37628.1 - 7.7e-71 237.9 0.0 1.2e-70 237.3 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.19 KXH37628.1 - 5.4e-38 129.4 0.0 2.7e-37 127.2 0.0 2.1 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_carb_N PF00289.22 KXH37628.1 - 3.1e-37 127.5 0.0 7.5e-37 126.2 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_lipoyl PF00364.22 KXH37628.1 - 1.3e-10 41.0 1.5 3.6e-08 33.1 0.1 3.5 3 0 0 3 3 3 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 KXH37628.1 - 5.6e-07 29.3 0.0 1.7e-06 27.7 0.0 1.8 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.6 KXH37628.1 - 2.6e-06 27.2 0.4 0.0005 19.8 0.0 3.0 3 0 0 3 3 3 1 Biotin-lipoyl like HlyD_3 PF13437.6 KXH37628.1 - 2.8e-05 24.8 0.6 0.51 11.1 0.0 3.2 3 0 0 3 3 3 2 HlyD family secretion protein ATP-grasp_3 PF02655.14 KXH37628.1 - 0.0043 17.1 0.0 0.0093 16.0 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 KXH37628.1 - 0.0094 15.6 0.0 0.056 13.0 0.0 2.0 1 1 0 1 1 1 1 RimK-like ATP-grasp domain CoA_binding_2 PF13380.6 KXH37628.1 - 0.01 16.3 0.0 0.42 11.1 0.0 3.0 2 1 0 2 2 2 0 CoA binding domain HlyD_D23 PF16576.5 KXH37628.1 - 0.024 13.9 0.2 0.88 8.7 0.0 3.0 3 0 0 3 3 3 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion DUF3182 PF11379.8 KXH37628.1 - 0.053 12.5 0.0 0.086 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3182) ATPgrasp_ST PF14397.6 KXH37628.1 - 0.075 12.3 0.0 0.39 9.9 0.0 2.0 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp Putative_PNPOx PF01243.20 KXH37629.1 - 8.9e-15 54.7 0.0 1.3e-13 51.0 0.0 2.1 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.7 KXH37629.1 - 0.00051 20.1 0.0 0.053 13.5 0.0 2.2 2 0 0 2 2 2 2 Pyridoxamine 5'-phosphate oxidase Methyltransf_23 PF13489.6 KXH37630.1 - 4.6e-16 59.1 0.0 7.6e-16 58.4 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH37630.1 - 5.2e-13 49.5 0.0 1.4e-12 48.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH37630.1 - 1.7e-09 38.3 0.1 7.5e-09 36.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH37630.1 - 4.1e-09 37.0 0.0 9.2e-09 35.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH37630.1 - 8.8e-09 35.3 0.0 6.2e-08 32.6 0.0 2.2 1 1 1 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXH37630.1 - 7.4e-05 22.2 0.0 0.00019 20.9 0.0 1.6 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 KXH37630.1 - 0.00014 21.3 0.0 0.00073 19.0 0.0 1.9 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.14 KXH37630.1 - 0.00016 21.3 0.0 0.00052 19.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.18 KXH37630.1 - 0.00086 18.7 0.0 0.0089 15.3 0.0 2.3 2 1 0 2 2 2 1 O-methyltransferase domain CMAS PF02353.20 KXH37630.1 - 0.059 12.7 0.0 0.14 11.4 0.0 1.5 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Gln-synt_C PF00120.24 KXH37631.1 - 2.8e-86 289.6 0.0 3.8e-86 289.2 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain adh_short_C2 PF13561.6 KXH37632.1 - 4.7e-58 196.5 0.3 5.4e-58 196.3 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXH37632.1 - 4.2e-41 140.6 0.2 5.2e-41 140.3 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXH37632.1 - 1.4e-07 31.6 1.3 2.1e-07 31.1 1.3 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KXH37632.1 - 0.00017 21.5 0.1 0.00031 20.7 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_25 PF13649.6 KXH37632.1 - 0.0019 18.9 0.0 0.0036 18.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain ChuX_HutX PF06228.13 KXH37632.1 - 0.002 17.9 0.0 1.2 8.9 0.0 2.3 1 1 1 2 2 2 2 Haem utilisation ChuX/HutX THF_DHG_CYH_C PF02882.19 KXH37632.1 - 0.04 13.2 0.1 0.14 11.4 0.0 1.9 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Polysacc_synt_2 PF02719.15 KXH37632.1 - 0.064 12.4 0.0 0.093 11.8 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein UDPG_MGDP_dh_N PF03721.14 KXH37632.1 - 0.088 12.4 0.1 0.13 11.8 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ICL PF00463.21 KXH37633.1 - 3.4e-201 669.3 0.2 3.9e-201 669.1 0.2 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 KXH37633.1 - 2.3e-12 46.9 0.1 1.5e-10 41.0 0.0 2.3 2 0 0 2 2 2 2 Phosphoenolpyruvate phosphomutase Citrate_synt PF00285.21 KXH37634.1 - 1.2e-101 340.4 0.0 1.5e-101 340.1 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain DUF4360 PF14273.6 KXH37635.1 - 5e-65 218.7 2.2 5.7e-65 218.5 2.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Sulfate_transp PF00916.20 KXH37636.1 - 5.5e-88 295.3 22.8 7.4e-88 294.8 22.8 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KXH37636.1 - 2.5e-12 46.4 0.0 4.4e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 KXH37636.1 - 0.012 16.0 0.0 0.026 14.9 0.0 1.6 1 0 0 1 1 1 0 STAS domain DUF2070 PF09843.9 KXH37637.1 - 9.4 4.4 9.2 14 3.8 9.2 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Lactamase_B PF00753.27 KXH37638.1 - 6.1e-18 65.5 4.3 1.3e-17 64.5 4.3 1.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KXH37638.1 - 0.00069 19.2 0.3 0.0012 18.4 0.3 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Scytalone_dh PF02982.14 KXH37638.1 - 0.028 14.2 0.0 0.068 13.0 0.0 1.6 1 0 0 1 1 1 0 Scytalone dehydratase Pyr_redox_2 PF07992.14 KXH37639.1 - 1.1e-11 44.6 0.0 7.1e-08 32.0 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXH37639.1 - 0.003 17.2 0.0 0.0058 16.3 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KXH37639.1 - 0.026 14.5 0.0 0.12 12.4 0.0 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 KXH37639.1 - 0.17 11.1 0.0 0.81 8.9 0.0 1.9 2 0 0 2 2 2 0 FAD binding domain Methyltransf_23 PF13489.6 KXH37640.1 - 9.7e-22 77.6 0.0 1.3e-21 77.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH37640.1 - 5.9e-09 36.5 0.0 1.1e-08 35.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH37640.1 - 1.2e-05 26.0 0.0 4.2e-05 24.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH37640.1 - 2.6e-05 24.8 0.0 4.2e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH37640.1 - 3.1e-05 23.8 0.0 0.00017 21.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXH37640.1 - 0.017 14.7 0.0 0.028 13.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_4 PF02390.17 KXH37640.1 - 0.065 12.7 0.0 0.065 12.7 0.0 1.9 3 0 0 3 3 3 0 Putative methyltransferase CMAS PF02353.20 KXH37640.1 - 0.19 11.0 0.0 0.51 9.6 0.0 1.7 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase His_Phos_1 PF00300.22 KXH37641.1 - 5.3e-13 49.1 0.0 1.7e-08 34.4 0.0 2.3 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) Fungal_trans_2 PF11951.8 KXH37642.1 - 1.7e-12 46.9 5.8 4e-12 45.7 5.8 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH37642.1 - 2.2e-06 27.7 7.3 4e-06 26.8 7.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain stn_TNFRSF12A PF12191.8 KXH37644.1 - 0.045 14.0 0.1 0.11 12.7 0.1 1.6 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain WH2 PF02205.20 KXH37645.1 - 8.6e-12 44.5 2.0 1.2e-10 40.9 0.4 2.9 3 0 0 3 3 3 1 WH2 motif Phage_holin_3_6 PF07332.11 KXH37647.1 - 0.00012 22.1 0.1 0.00012 22.1 0.1 2.5 1 1 2 3 3 3 1 Putative Actinobacterial Holin-X, holin superfamily III 7tm_7 PF08395.12 KXH37647.1 - 0.0057 15.9 5.7 0.0085 15.3 5.7 1.1 1 0 0 1 1 1 1 7tm Chemosensory receptor DUF2207 PF09972.9 KXH37647.1 - 2.1 7.0 3.6 4.3 6.0 3.6 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Cyt_bd_oxida_II PF02322.15 KXH37647.1 - 2.7 7.3 10.4 6.1 6.1 10.4 1.4 1 1 0 1 1 1 0 Cytochrome bd terminal oxidase subunit II CHORD PF04968.12 KXH37648.1 - 2.4e-49 165.9 19.2 1.3e-25 89.9 6.3 2.2 2 0 0 2 2 2 2 CHORD CS PF04969.16 KXH37648.1 - 2.2e-12 47.8 0.1 3.2e-12 47.3 0.1 1.3 1 0 0 1 1 1 1 CS domain DUF836 PF05768.14 KXH37649.1 - 2.5e-12 47.0 0.0 3e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.24 KXH37649.1 - 0.00089 19.4 0.0 0.0017 18.5 0.0 1.6 1 0 0 1 1 1 1 Glutaredoxin HpcH_HpaI PF03328.14 KXH37650.1 - 1.7e-31 109.1 0.0 2.2e-31 108.7 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family SHS2_Rpb7-N PF03876.17 KXH37651.1 - 1.6e-15 57.2 0.0 2.5e-15 56.6 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 KXH37651.1 - 9.7e-12 45.1 0.0 1.6e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 S1 RNA binding domain DUF962 PF06127.11 KXH37652.1 - 1.6e-26 92.2 0.0 3e-26 91.3 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF962) MIG-14_Wnt-bd PF06664.12 KXH37652.1 - 0.1 11.8 0.1 0.23 10.7 0.0 1.5 2 0 0 2 2 2 0 Wnt-binding factor required for Wnt secretion Promethin PF16015.5 KXH37652.1 - 3.3 7.7 8.1 0.16 11.9 2.6 1.7 2 0 0 2 2 2 0 Promethin Zip PF02535.22 KXH37653.1 - 2 7.6 3.6 3.3 6.9 3.6 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter PPP4R2 PF09184.11 KXH37654.1 - 0.21 11.2 1.4 0.33 10.5 1.4 1.3 1 0 0 1 1 1 0 PPP4R2 MOSC PF03473.17 KXH37658.1 - 1.6e-35 121.9 0.0 3.4e-35 120.9 0.0 1.6 1 0 0 1 1 1 1 MOSC domain Aminotran_5 PF00266.19 KXH37658.1 - 5.9e-23 81.4 0.0 1.1e-22 80.5 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class-V MOSC_N PF03476.16 KXH37658.1 - 2.8e-21 75.6 0.0 5.2e-21 74.8 0.0 1.5 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain AAA_22 PF13401.6 KXH37659.1 - 2.1e-15 57.2 0.0 8e-15 55.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KXH37659.1 - 1.8e-14 54.5 1.8 2.6e-13 50.7 0.1 3.1 2 2 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 KXH37659.1 - 3.5e-11 43.7 0.0 1e-10 42.2 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Cdc6_C PF09079.11 KXH37659.1 - 1.9e-07 30.9 0.2 1.8e-06 27.8 0.2 2.4 1 1 0 1 1 1 1 CDC6, C terminal winged helix domain TniB PF05621.11 KXH37659.1 - 7.3e-07 28.8 0.0 1.4e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Bacterial TniB protein AAA_lid_10 PF17872.1 KXH37659.1 - 6.1e-06 26.3 0.1 2.3e-05 24.4 0.0 2.0 2 0 0 2 2 1 1 AAA lid domain AAA_19 PF13245.6 KXH37659.1 - 5.7e-05 23.5 0.0 0.00019 21.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 KXH37659.1 - 0.0012 18.8 0.0 0.0039 17.1 0.0 1.8 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_7 PF12775.7 KXH37659.1 - 0.0016 18.0 0.2 0.0056 16.2 0.1 1.9 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_30 PF13604.6 KXH37659.1 - 0.0017 18.1 0.0 0.0071 16.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KXH37659.1 - 0.0017 18.3 0.0 0.0034 17.3 0.0 1.5 1 0 0 1 1 1 1 NACHT domain Rad17 PF03215.15 KXH37659.1 - 0.0023 17.9 0.4 0.035 14.0 0.1 2.2 2 0 0 2 2 2 1 Rad17 P-loop domain DUF815 PF05673.13 KXH37659.1 - 0.0042 16.3 0.0 0.0099 15.1 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) NB-ARC PF00931.22 KXH37659.1 - 0.0053 16.0 0.0 0.011 14.9 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain Sigma54_activat PF00158.26 KXH37659.1 - 0.0097 15.6 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_14 PF13173.6 KXH37659.1 - 0.013 15.5 0.0 0.029 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KXH37659.1 - 0.017 14.8 0.0 0.033 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KXH37659.1 - 0.025 15.0 0.0 0.073 13.5 0.0 1.8 1 0 0 1 1 1 0 RNA helicase SRPRB PF09439.10 KXH37659.1 - 0.027 13.9 0.0 0.067 12.6 0.0 1.6 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit KAP_NTPase PF07693.14 KXH37659.1 - 0.034 13.4 0.0 0.046 12.9 0.0 1.4 1 1 0 1 1 1 0 KAP family P-loop domain AAA_5 PF07728.14 KXH37659.1 - 0.068 13.2 0.0 0.29 11.2 0.0 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 KXH37659.1 - 0.079 13.5 0.0 0.19 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 KXH37659.1 - 0.14 11.9 0.2 1 9.1 0.0 2.3 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain Rrf2 PF02082.20 KXH37659.1 - 0.16 12.4 0.0 0.49 10.8 0.0 1.8 1 0 0 1 1 1 0 Transcriptional regulator Arrestin_N PF00339.29 KXH37660.1 - 5e-19 68.8 0.0 3.3e-18 66.1 0.0 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 KXH37660.1 - 7.9e-06 26.4 0.1 0.00015 22.2 0.0 2.5 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain UQ_con PF00179.26 KXH37663.1 - 1.6e-52 176.8 0.0 1.8e-52 176.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KXH37663.1 - 0.0048 16.6 0.0 0.0059 16.3 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KXH37663.1 - 0.037 14.3 0.0 0.045 14.0 0.0 1.2 1 0 0 1 1 1 0 RWD domain UEV PF05743.13 KXH37663.1 - 0.046 13.6 0.0 0.072 13.0 0.0 1.3 1 0 0 1 1 1 0 UEV domain Acyl-CoA_dh_N PF02771.16 KXH37664.1 - 1.6e-26 93.2 0.7 3.6e-26 92.0 0.7 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 KXH37664.1 - 3.5e-22 79.2 0.1 6.2e-22 78.4 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KXH37664.1 - 1e-17 64.1 0.0 2.5e-17 62.9 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KXH37664.1 - 1.3e-05 25.5 0.1 2.6e-05 24.5 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain ADK PF00406.22 KXH37666.1 - 1.6e-09 38.1 0.0 2.3e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KXH37666.1 - 0.00019 21.9 0.0 0.00029 21.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain Radical_SAM PF04055.21 KXH37667.1 - 7.1e-15 55.8 0.3 1.5e-14 54.7 0.3 1.6 1 1 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 KXH37667.1 - 9.5e-07 29.2 0.1 3.4e-06 27.4 0.0 1.8 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 KXH37667.1 - 0.00057 20.0 0.1 0.0019 18.3 0.0 1.8 2 0 0 2 2 2 1 4Fe-4S single cluster domain SYS1 PF09801.9 KXH37670.1 - 2.5e-45 154.2 0.1 2.8e-45 154.0 0.1 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network TPPK_C PF12555.8 KXH37670.1 - 0.0079 16.2 0.6 0.0079 16.2 0.6 2.8 3 0 0 3 3 3 1 Thiamine pyrophosphokinase C terminal COX6B PF02297.17 KXH37671.1 - 1.4e-23 82.9 3.7 1.9e-23 82.5 3.7 1.2 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb IL28A PF15177.6 KXH37671.1 - 0.003 17.4 0.1 0.005 16.7 0.1 1.4 1 1 0 1 1 1 1 Interleukin-28A PIP5K PF01504.18 KXH37672.1 - 7.3e-102 340.3 0.2 1.5e-101 339.3 0.2 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Yae1_N PF09811.9 KXH37674.1 - 3.8e-13 48.9 1.9 6.6e-13 48.1 1.9 1.4 1 0 0 1 1 1 1 Essential protein Yae1, N terminal Pirin PF02678.16 KXH37675.1 - 1.4e-24 86.1 0.9 4e-24 84.7 0.9 1.7 1 1 0 1 1 1 1 Pirin Cupin_2 PF07883.11 KXH37675.1 - 9.2e-05 22.1 3.3 0.033 13.9 1.1 3.0 2 1 0 2 2 2 2 Cupin domain AlgF PF11182.8 KXH37675.1 - 0.058 13.2 0.2 7.8 6.2 0.0 2.7 2 1 1 3 3 3 0 Alginate O-acetyl transferase AlgF MelC1 PF06236.11 KXH37675.1 - 0.067 13.3 0.2 0.16 12.1 0.0 1.9 2 1 0 2 2 2 0 Tyrosinase co-factor MelC1 HET PF06985.11 KXH37677.1 - 5.4e-11 43.0 0.0 9.9e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) UIM PF02809.20 KXH37677.1 - 0.019 14.9 0.2 0.64 10.1 0.0 2.9 2 0 0 2 2 2 0 Ubiquitin interaction motif Polyoma_agno PF01736.16 KXH37677.1 - 0.81 9.5 3.0 14 5.5 0.2 2.7 1 1 1 2 2 2 0 Polyomavirus agnoprotein GAT PF03127.14 KXH37678.1 - 1e-19 70.6 1.0 2.4e-18 66.2 0.5 2.5 2 0 0 2 2 2 1 GAT domain VHS PF00790.19 KXH37678.1 - 0.0018 18.2 0.0 0.0047 16.8 0.0 1.7 1 0 0 1 1 1 1 VHS domain DUF3110 PF11360.8 KXH37678.1 - 0.044 14.0 0.2 6.5 7.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3110) UBA_4 PF14555.6 KXH37679.1 - 1.5e-10 40.7 0.0 2.9e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.20 KXH37679.1 - 2.8e-06 27.4 0.0 1.1e-05 25.5 0.0 2.1 1 1 0 1 1 1 1 UBX domain SUB1_ProdP9 PF18213.1 KXH37679.1 - 0.0024 17.7 0.0 0.0068 16.2 0.0 1.7 1 0 0 1 1 1 1 SUB1 protease Prodomain ProdP9 DUF612 PF04747.12 KXH37679.1 - 0.21 10.7 11.5 0.32 10.0 11.5 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF612 Pan3_PK PF18101.1 KXH37680.1 - 4.4e-63 211.4 0.1 6.8e-63 210.8 0.1 1.3 1 0 0 1 1 1 1 Pan3 Pseudokinase domain Pkinase PF00069.25 KXH37680.1 - 3.5e-05 23.3 0.0 6.2e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXH37680.1 - 0.081 12.2 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase DUF2205 PF10224.9 KXH37682.1 - 3.9e-35 119.7 0.3 6.9e-35 118.9 0.3 1.4 1 0 0 1 1 1 1 Short coiled-coil protein AAA_32 PF13654.6 KXH37682.1 - 0.032 13.0 0.0 0.039 12.8 0.0 1.1 1 0 0 1 1 1 0 AAA domain Nramp PF01566.18 KXH37683.1 - 5.7e-92 308.4 13.7 1.5e-91 307.0 13.7 1.7 1 1 0 1 1 1 1 Natural resistance-associated macrophage protein Ribonuc_L-PSP PF01042.21 KXH37684.1 - 7.5e-22 77.6 0.0 9.1e-22 77.3 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Fungal_trans PF04082.18 KXH37686.1 - 2.3e-21 76.0 0.1 3.4e-21 75.5 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH37686.1 - 5.7e-07 29.6 11.3 1.3e-06 28.4 11.3 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KXH37686.1 - 0.0047 15.8 0.1 0.023 13.5 0.0 2.1 3 0 0 3 3 3 1 Fungal specific transcription factor domain Bac_rhodopsin PF01036.18 KXH37687.1 - 2.2e-60 204.0 11.9 2.9e-60 203.6 11.9 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein FtsX PF02687.21 KXH37687.1 - 0.13 12.8 0.1 0.13 12.8 0.1 2.6 2 2 1 3 3 3 0 FtsX-like permease family RPE65 PF03055.15 KXH37688.1 - 1.2e-123 413.7 0.0 1.4e-123 413.6 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein E1-E2_ATPase PF00122.20 KXH37689.1 - 1.3e-38 132.3 19.0 2.9e-32 111.6 0.0 3.8 3 1 1 4 4 4 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 KXH37689.1 - 2.5e-27 95.8 5.2 2.5e-27 95.8 5.2 2.3 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KXH37689.1 - 1.7e-17 64.4 1.4 1.1e-15 58.6 1.4 3.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KXH37689.1 - 5.6e-14 51.6 0.0 1.2e-13 50.5 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 KXH37689.1 - 4e-13 49.3 0.0 8e-13 48.3 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KXH37689.1 - 4.7e-06 26.5 1.5 6.2e-05 22.9 0.5 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase IncE PF17627.2 KXH37689.1 - 0.052 13.6 3.2 0.067 13.2 0.9 2.4 2 0 0 2 2 2 0 Inclusion membrane protein E Sulfotransfer_4 PF17784.1 KXH37690.1 - 3.4e-52 177.4 0.0 4e-52 177.2 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain DUF866 PF05907.13 KXH37690.1 - 0.0022 17.9 0.2 0.003 17.5 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) Sulfotransfer_3 PF13469.6 KXH37690.1 - 0.0035 17.7 0.1 2.4 8.5 0.0 2.3 1 1 1 2 2 2 2 Sulfotransferase family HsbA PF12296.8 KXH37691.1 - 1.3e-27 96.6 17.5 1.3e-27 96.6 17.5 1.8 2 0 0 2 2 2 1 Hydrophobic surface binding protein A Podoplanin PF05808.11 KXH37691.1 - 0.0046 17.1 1.3 0.0065 16.6 1.3 1.2 1 0 0 1 1 1 1 Podoplanin Laminin_II PF06009.12 KXH37691.1 - 0.01 15.8 4.7 0.077 13.0 0.6 2.3 1 1 1 2 2 2 0 Laminin Domain II NPV_P10 PF05531.12 KXH37691.1 - 0.031 14.7 11.7 0.33 11.4 2.1 2.9 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Sec8_exocyst PF04048.14 KXH37691.1 - 0.058 13.3 2.2 0.074 12.9 1.5 1.5 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain TrbC PF04956.13 KXH37691.1 - 0.069 13.4 1.0 0.069 13.4 1.0 2.9 2 1 1 3 3 3 0 TrbC/VIRB2 family ApoLp-III PF07464.11 KXH37691.1 - 0.54 10.3 7.7 0.41 10.7 1.4 2.6 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) SNF2_N PF00176.23 KXH37695.1 - 3.9e-66 223.1 0.3 6.6e-66 222.4 0.3 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KXH37695.1 - 7.1e-19 68.2 0.0 4.2e-18 65.7 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXH37695.1 - 2.9e-09 37.2 0.0 7.3e-09 35.9 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HSA PF07529.13 KXH37695.1 - 0.00092 19.5 7.1 0.00092 19.5 7.1 2.5 2 0 0 2 2 2 1 HSA HDA2-3 PF11496.8 KXH37695.1 - 0.0061 15.8 0.2 0.99 8.5 0.0 2.6 2 1 0 2 2 2 2 Class II histone deacetylase complex subunits 2 and 3 NDUF_B8 PF05821.11 KXH37696.1 - 4.6e-07 29.9 2.2 7.2e-07 29.2 2.1 1.3 1 1 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) Glyco_hydro_1 PF00232.18 KXH37698.1 - 6.9e-73 245.6 0.0 3.1e-72 243.5 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 1 Cellulase PF00150.18 KXH37698.1 - 0.012 15.0 0.0 0.037 13.4 0.0 1.7 2 0 0 2 2 2 0 Cellulase (glycosyl hydrolase family 5) AMP-binding PF00501.28 KXH37699.1 - 5.5e-19 68.1 0.0 1.4e-18 66.7 0.0 1.7 1 1 0 1 1 1 1 AMP-binding enzyme ADH_N PF08240.12 KXH37700.1 - 0.00032 20.5 0.0 0.0012 18.7 0.0 1.9 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain MFS_1 PF07690.16 KXH37701.1 - 2.1e-27 96.0 63.0 8.1e-27 94.1 60.5 3.0 2 1 0 2 2 2 1 Major Facilitator Superfamily F-box-like PF12937.7 KXH37702.1 - 0.0015 18.4 0.4 0.0035 17.2 0.4 1.7 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KXH37702.1 - 0.04 14.3 6.1 0.36 11.3 0.2 3.6 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) MAPEG PF01124.18 KXH37703.1 - 0.0012 18.8 1.7 0.0037 17.2 1.6 1.8 1 1 0 1 1 1 1 MAPEG family p450 PF00067.22 KXH37704.1 - 4.1e-48 164.3 0.0 5.9e-48 163.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Acyl_transf_1 PF00698.21 KXH37704.1 - 0.086 12.3 0.0 0.19 11.2 0.1 1.5 2 0 0 2 2 2 0 Acyl transferase domain Trehalase_Ca-bi PF07492.11 KXH37704.1 - 0.53 10.1 1.8 0.91 9.3 1.8 1.3 1 0 0 1 1 1 0 Neutral trehalase Ca2+ binding domain Amino_oxidase PF01593.24 KXH37705.1 - 3.3e-15 56.3 0.1 1.3e-14 54.3 0.1 2.1 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KXH37705.1 - 2.5e-14 53.2 0.1 6.5e-14 51.9 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KXH37705.1 - 6.6e-09 35.6 0.0 8.8e-07 28.6 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KXH37705.1 - 1.5e-06 27.6 0.4 2.5e-06 26.8 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KXH37705.1 - 1.8e-05 24.5 0.5 0.00011 21.9 0.5 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KXH37705.1 - 1.9e-05 23.6 0.3 3.6e-05 22.7 0.1 1.5 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 KXH37705.1 - 4.7e-05 23.9 0.8 0.0015 19.0 0.2 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXH37705.1 - 0.00018 20.9 0.0 0.00047 19.5 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXH37705.1 - 0.014 14.7 0.0 0.024 13.9 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXH37705.1 - 0.014 14.7 0.0 0.033 13.4 0.0 1.6 1 0 0 1 1 1 0 Thi4 family FAD_binding_3 PF01494.19 KXH37705.1 - 0.023 14.0 0.2 0.037 13.3 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain DUF4945 PF16303.5 KXH37705.1 - 0.026 14.5 0.0 0.12 12.4 0.0 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4945) ApbA PF02558.16 KXH37705.1 - 0.036 13.7 0.0 0.056 13.1 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA GIDA PF01134.22 KXH37705.1 - 0.12 11.4 0.1 0.18 10.9 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A NPP1 PF05630.11 KXH37706.1 - 7.9e-64 215.4 0.0 9.1e-64 215.2 0.0 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) Na_Ca_ex PF01699.24 KXH37707.1 - 5.3e-26 91.4 38.3 1.3e-11 44.7 17.4 3.0 3 0 0 3 3 3 3 Sodium/calcium exchanger protein DUF2721 PF11026.8 KXH37707.1 - 1 9.3 0.0 1 9.3 0.0 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF2721) C2 PF00168.30 KXH37709.1 - 1.5e-10 41.3 0.0 2.9e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 C2 domain zf-C2H2 PF00096.26 KXH37710.1 - 0.0074 16.7 0.5 0.031 14.7 0.5 2.2 1 0 0 1 1 1 1 Zinc finger, C2H2 type DUF1387 PF07139.11 KXH37710.1 - 0.38 10.4 4.7 0.57 9.9 4.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) NTPase_I-T PF01931.18 KXH37711.1 - 3e-60 202.7 0.0 3.4e-60 202.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF84 Evr1_Alr PF04777.13 KXH37712.1 - 3.8e-26 91.5 0.0 5.5e-26 91.0 0.0 1.2 1 0 0 1 1 1 1 Erv1 / Alr family Proteasome PF00227.26 KXH37713.1 - 1.7e-47 161.4 0.3 1.9e-47 161.2 0.3 1.0 1 0 0 1 1 1 1 Proteasome subunit PX PF00787.24 KXH37714.1 - 5.5e-25 87.6 0.0 6.3e-25 87.4 0.0 1.0 1 0 0 1 1 1 1 PX domain PRP21_like_P PF12230.8 KXH37715.1 - 2.6e-55 187.7 21.2 1.4e-53 182.0 21.2 2.2 1 1 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.20 KXH37715.1 - 3.7e-40 135.7 4.7 1.2e-20 73.2 0.2 2.5 2 0 0 2 2 2 2 Surp module NinF PF05810.12 KXH37715.1 - 0.0052 16.6 0.1 0.015 15.1 0.1 1.8 1 0 0 1 1 1 1 NinF protein zf_UBZ PF18439.1 KXH37715.1 - 0.011 15.4 0.4 0.019 14.6 0.4 1.4 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger PMT PF02366.18 KXH37716.1 - 1.4e-81 273.7 14.7 1.4e-81 273.7 14.7 1.9 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 KXH37716.1 - 1.2e-68 230.6 12.4 1.2e-68 230.6 12.4 2.5 3 0 0 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 KXH37716.1 - 1.9e-45 155.0 0.0 4.4e-45 153.8 0.0 1.6 1 1 0 1 1 1 1 MIR domain Sec2p PF06428.11 KXH37717.1 - 2.3e-25 88.3 17.6 2.3e-25 88.3 17.6 2.9 3 0 0 3 3 3 1 GDP/GTP exchange factor Sec2p DUF3348 PF11828.8 KXH37717.1 - 0.76 9.4 16.9 5.2 6.7 13.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3348) DUF5339 PF17274.2 KXH37717.1 - 2.6 8.9 10.7 4.6 8.2 0.5 2.9 2 0 0 2 2 2 0 Family of unknown function (DUF5339) Gln_amidase PF15644.6 KXH37720.1 - 0.048 14.7 0.0 0.18 12.9 0.0 1.9 2 1 0 2 2 2 0 Papain fold toxin 1, glutamine deamidase DUF1218 PF06749.12 KXH37721.1 - 0.056 14.0 3.3 0.48 11.0 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1218) Semialdhyde_dhC PF02774.18 KXH37722.1 - 2.2e-38 132.2 0.0 2.9e-38 131.8 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 KXH37722.1 - 1.2e-29 103.2 0.0 3.7e-29 101.6 0.0 1.8 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 KXH37722.1 - 0.0049 17.7 0.0 0.01 16.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DapB_N PF01113.20 KXH37722.1 - 0.021 15.0 0.0 0.055 13.6 0.0 1.7 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Sacchrp_dh_NADP PF03435.18 KXH37722.1 - 0.1 12.9 0.0 0.58 10.4 0.0 2.1 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain TRI12 PF06609.13 KXH37723.1 - 1.4e-37 129.4 14.4 1.9e-37 129.0 14.4 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 KXH37723.1 - 1.2e-23 83.6 38.2 1.1e-22 80.4 37.5 2.1 2 0 0 2 2 2 1 Major Facilitator Superfamily RRM_1 PF00076.22 KXH37724.1 - 1.7e-11 43.7 0.0 5.3e-09 35.8 0.0 2.8 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CIA30 PF08547.12 KXH37725.1 - 2.1e-46 157.9 0.0 2.9e-46 157.4 0.0 1.2 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) ANAPC5 PF12862.7 KXH37726.1 - 1.5e-31 108.3 4.4 2.2e-31 107.8 2.1 2.5 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 5 TPR_10 PF13374.6 KXH37726.1 - 0.03 14.2 5.8 2.3 8.2 0.3 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 KXH37726.1 - 0.092 12.9 2.7 20 5.6 0.1 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 KXH37726.1 - 0.094 12.8 6.5 1.2 9.4 0.0 4.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_21 PF09976.9 KXH37726.1 - 0.18 11.5 5.2 0.98 9.1 0.5 3.8 3 1 1 4 4 4 0 Tetratricopeptide repeat-like domain TPR_14 PF13428.6 KXH37726.1 - 0.53 11.2 18.9 0.92 10.5 0.3 6.4 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_19 PF14559.6 KXH37726.1 - 2.6 8.6 20.1 12 6.5 3.5 5.9 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.14 KXH37726.1 - 3.7 8.4 8.6 9.5 7.2 0.1 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat COX6A PF02046.15 KXH37727.1 - 3.4e-50 169.2 3.4 3.8e-50 169.1 3.4 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa DUF2933 PF11666.8 KXH37727.1 - 0.075 13.1 0.1 0.13 12.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2933) Exo_endo_phos PF03372.23 KXH37728.1 - 5.4e-10 39.2 0.0 1.4e-09 37.8 0.0 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 KXH37728.1 - 0.016 15.0 0.0 1 9.3 0.0 2.4 1 1 1 2 2 2 0 Endonuclease-reverse transcriptase MFS_1 PF07690.16 KXH37729.1 - 7.2e-11 41.6 42.7 7.2e-11 41.6 42.7 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 KXH37729.1 - 5e-06 26.3 4.2 5e-06 26.3 4.2 2.7 2 1 1 3 3 3 1 Ion channel regulatory protein UNC-93 GARS_A PF01071.19 KXH37730.1 - 6.5e-83 277.3 0.0 1e-82 276.6 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain AIRS_C PF02769.22 KXH37730.1 - 1.2e-33 116.4 0.4 2.4e-32 112.3 0.2 2.5 2 0 0 2 2 2 1 AIR synthase related protein, C-terminal domain GARS_N PF02844.15 KXH37730.1 - 2e-33 115.0 0.0 5.7e-33 113.6 0.0 1.8 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.16 KXH37730.1 - 8.1e-26 90.1 0.6 2.7e-25 88.4 0.2 2.2 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.24 KXH37730.1 - 2.1e-14 53.9 2.1 1.5e-13 51.2 1.9 2.5 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain CPSase_L_D2 PF02786.17 KXH37730.1 - 8.4e-06 25.4 0.1 2e-05 24.2 0.1 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp PF02222.22 KXH37730.1 - 0.00022 20.9 0.0 0.00057 19.5 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 KXH37730.1 - 0.00035 20.6 0.0 0.00097 19.2 0.0 1.8 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.6 KXH37730.1 - 0.0017 18.0 0.0 0.0037 16.9 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 KXH37730.1 - 0.091 12.3 0.3 0.27 10.8 0.0 1.9 2 0 0 2 2 2 0 RimK-like ATP-grasp domain ATP-grasp_5 PF13549.6 KXH37730.1 - 0.094 12.2 0.0 0.24 10.8 0.0 1.7 1 0 0 1 1 1 0 ATP-grasp domain TPR_16 PF13432.6 KXH37731.1 - 1e-07 32.5 11.5 1.6 9.5 0.6 7.5 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_11 PF13414.6 KXH37731.1 - 1.1e-06 28.2 3.5 0.047 13.4 0.0 5.3 6 0 0 6 6 6 2 TPR repeat TPR_20 PF14561.6 KXH37731.1 - 4.5e-06 26.9 4.8 2 8.8 0.0 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 KXH37731.1 - 7e-06 26.5 19.1 0.074 13.6 0.0 6.6 5 2 2 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.6 KXH37731.1 - 2.3e-05 24.5 1.2 0.12 12.8 0.0 5.6 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 KXH37731.1 - 0.00051 19.9 25.0 2.2 8.6 0.0 8.3 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_1 PF00515.28 KXH37731.1 - 0.0014 18.4 15.0 28 4.8 0.0 8.0 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_14 PF13428.6 KXH37731.1 - 0.0039 17.9 23.7 3.7 8.6 0.1 8.7 7 1 3 10 10 10 2 Tetratricopeptide repeat DUF3655 PF12379.8 KXH37731.1 - 0.011 16.0 0.0 0.038 14.3 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3655) TPR_9 PF13371.6 KXH37731.1 - 0.012 15.7 11.8 0.023 14.8 0.1 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.6 KXH37731.1 - 0.093 13.0 18.5 0.3 11.4 2.0 6.1 8 0 0 8 8 7 0 Tetratricopeptide repeat DUF2989 PF11207.8 KXH37731.1 - 0.15 11.8 0.7 0.32 10.7 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2989) ANAPC3 PF12895.7 KXH37731.1 - 0.22 11.8 14.2 3.9 7.8 5.2 4.7 6 0 0 6 6 6 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 KXH37731.1 - 0.5 10.7 14.3 27 5.3 0.0 7.1 10 0 0 10 10 9 0 Tetratricopeptide repeat SAM_2 PF07647.17 KXH37732.1 - 1.7e-09 37.6 0.1 2.8e-09 37.0 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KXH37732.1 - 3.4e-05 24.2 0.3 5.6e-05 23.5 0.3 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) IGR PF09597.10 KXH37732.1 - 0.021 14.9 0.3 0.057 13.5 0.2 1.7 2 0 0 2 2 2 0 IGR protein motif DUF4508 PF14969.6 KXH37733.1 - 0.026 14.7 0.1 0.048 13.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4508) Ribosomal_L29e PF01779.17 KXH37734.1 - 8e-23 80.5 8.9 1.2e-22 79.9 8.9 1.3 1 0 0 1 1 1 1 Ribosomal L29e protein family Mito_carr PF00153.27 KXH37735.1 - 8.6e-57 189.1 0.3 7e-20 70.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Peptidase_C2 PF00648.21 KXH37736.1 - 9.8e-29 100.3 0.0 1.5e-28 99.7 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 KXH37736.1 - 2.8e-09 37.4 0.0 4.8e-06 26.9 0.0 3.7 2 1 0 2 2 2 1 Calpain large subunit, domain III Pkinase_Tyr PF07714.17 KXH37739.1 - 0.00093 18.6 0.1 0.032 13.5 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 KXH37739.1 - 0.015 14.6 0.0 0.033 13.6 0.0 1.5 1 0 0 1 1 1 0 Protein kinase domain zf-RING_UBOX PF13445.6 KXH37739.1 - 0.11 12.5 0.0 0.28 11.3 0.0 1.6 1 0 0 1 1 1 0 RING-type zinc-finger SWIM PF04434.17 KXH37740.1 - 0.0006 19.4 0.1 0.0006 19.4 0.1 1.7 2 0 0 2 2 2 1 SWIM zinc finger CbtA PF09490.10 KXH37741.1 - 8.6 6.0 12.6 1.6 8.5 2.2 2.5 2 1 0 2 2 2 0 Probable cobalt transporter subunit (CbtA) adh_short_C2 PF13561.6 KXH37743.1 - 2.2e-56 191.0 0.0 3e-56 190.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXH37743.1 - 8.6e-45 152.6 0.0 1.2e-44 152.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXH37743.1 - 9.5e-12 45.2 0.0 1.3e-11 44.8 0.0 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KXH37743.1 - 0.051 12.9 0.0 0.064 12.6 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) SnoaL_2 PF12680.7 KXH37744.1 - 0.011 16.4 0.0 0.026 15.2 0.0 1.6 1 0 0 1 1 1 0 SnoaL-like domain AA_permease PF00324.21 KXH37745.1 - 2.1e-141 471.8 35.8 2.6e-141 471.5 35.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KXH37745.1 - 1.1e-40 139.8 32.0 1.4e-40 139.5 32.0 1.1 1 0 0 1 1 1 1 Amino acid permease DUF4781 PF16013.5 KXH37745.1 - 0.086 11.6 2.5 0.13 11.0 0.9 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4781) PknG_TPR PF16918.5 KXH37745.1 - 0.15 10.7 0.2 0.23 10.2 0.2 1.2 1 0 0 1 1 1 0 Protein kinase G tetratricopeptide repeat Glyco_hydro_47 PF01532.20 KXH37746.1 - 1.2e-170 568.4 0.0 1.5e-170 568.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 2-oxoacid_dh PF00198.23 KXH37747.1 - 7.9e-77 257.8 0.1 1.1e-76 257.3 0.1 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KXH37747.1 - 9.2e-18 63.9 3.7 1.7e-17 63.0 3.7 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme HlyD_3 PF13437.6 KXH37747.1 - 0.0014 19.3 0.5 0.081 13.6 0.2 2.3 1 1 1 2 2 2 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 KXH37747.1 - 0.0014 18.4 0.4 0.37 10.7 0.0 2.4 1 1 1 2 2 2 2 Biotin-lipoyl like RnfC_N PF13375.6 KXH37747.1 - 0.066 13.2 1.2 3.3 7.7 0.0 3.1 1 1 2 3 3 3 0 RnfC Barrel sandwich hybrid domain FAM76 PF16046.5 KXH37747.1 - 0.65 9.3 8.5 12 5.1 5.6 2.1 2 0 0 2 2 2 0 FAM76 protein Trypan_PARP PF05887.11 KXH37747.1 - 0.73 9.8 17.8 1.3 9.0 17.8 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Presenilin PF01080.17 KXH37747.1 - 0.76 8.5 5.8 1.1 8.0 5.8 1.1 1 0 0 1 1 1 0 Presenilin Raftlin PF15250.6 KXH37747.1 - 1.7 7.3 5.7 2.4 6.8 5.7 1.1 1 0 0 1 1 1 0 Raftlin Ndc1_Nup PF09531.10 KXH37747.1 - 1.7 7.2 7.6 2.5 6.7 7.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF2052 PF09747.9 KXH37747.1 - 6.4 6.8 8.3 10 6.2 8.3 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DUF4551 PF15087.6 KXH37747.1 - 6.9 5.4 6.8 8.1 5.1 6.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Autophagy_act_C PF03987.15 KXH37748.1 - 3.4e-13 50.0 0.1 7.7e-13 48.8 0.0 1.6 1 1 1 2 2 2 1 Autophagocytosis associated protein, active-site domain RRM_1 PF00076.22 KXH37749.1 - 2.1e-09 37.1 0.0 6e-09 35.6 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KXH37749.1 - 1.2e-06 28.1 0.1 2.2e-06 27.2 0.0 1.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Calcipressin PF04847.12 KXH37749.1 - 0.016 15.0 0.3 0.027 14.2 0.0 1.5 2 0 0 2 2 2 0 Calcipressin Limkain-b1 PF11608.8 KXH37749.1 - 0.019 15.0 0.3 0.046 13.8 0.0 1.7 2 0 0 2 2 2 0 Limkain b1 WD40 PF00400.32 KXH37750.1 - 8e-18 64.5 9.4 0.00023 21.9 0.0 7.0 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXH37750.1 - 3.1e-07 30.6 0.0 0.02 15.2 0.0 4.1 4 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KXH37750.1 - 0.0017 18.3 0.1 3.9 7.5 0.0 3.1 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat zf-UBR PF02207.20 KXH37751.1 - 5.5e-19 68.1 12.1 1.5e-18 66.7 12.1 1.8 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 KXH37751.1 - 1.5e-08 34.3 0.0 3.9e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS WD40 PF00400.32 KXH37752.1 - 2e-50 167.7 16.1 2.3e-10 40.9 0.5 7.8 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXH37752.1 - 1.5e-21 76.5 0.0 0.00017 21.8 0.0 6.1 4 2 2 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KXH37752.1 - 4.5e-07 29.2 0.3 0.097 11.6 0.0 5.0 3 3 2 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein VID27 PF08553.10 KXH37752.1 - 0.00014 21.0 0.0 0.85 8.6 0.0 4.2 4 1 0 4 4 4 1 VID27 C-terminal WD40-like domain Nup160 PF11715.8 KXH37752.1 - 0.013 14.2 1.5 4.2 5.9 0.0 3.9 2 2 1 4 4 4 0 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 KXH37752.1 - 0.094 11.2 0.0 0.44 9.0 0.0 1.9 2 0 0 2 2 2 0 Cytochrome D1 heme domain Thiolase_N PF00108.23 KXH37755.1 - 2.4e-76 256.5 4.0 3.4e-76 256.0 4.0 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KXH37755.1 - 9.4e-41 138.3 0.2 2e-40 137.3 0.2 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KXH37755.1 - 0.0084 15.7 0.8 0.021 14.4 0.7 1.8 1 1 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III_C PF08541.10 KXH37755.1 - 0.012 15.8 0.0 0.056 13.6 0.0 2.2 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal NMO PF03060.15 KXH37756.1 - 3.4e-49 168.0 1.7 5.9e-48 163.9 1.7 1.9 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KXH37756.1 - 2.7e-14 52.9 0.0 2.7e-07 29.9 0.0 2.1 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KXH37756.1 - 0.00023 20.3 0.2 0.0004 19.5 0.2 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase His_biosynth PF00977.21 KXH37756.1 - 0.086 12.3 0.3 0.22 10.9 0.1 1.8 2 0 0 2 2 2 0 Histidine biosynthesis protein NanE PF04131.14 KXH37756.1 - 0.17 11.0 0.9 0.22 10.7 0.0 1.6 2 0 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase VASP_tetra PF08776.11 KXH37756.1 - 1.9 8.1 5.6 7.5 6.2 0.7 2.5 2 0 0 2 2 2 0 VASP tetramerisation domain dsrm PF00035.26 KXH37757.1 - 0.0032 18.2 0.0 0.0053 17.5 0.0 1.4 1 0 0 1 1 1 1 Double-stranded RNA binding motif DND1_DSRM PF14709.7 KXH37757.1 - 0.02 15.2 0.0 0.087 13.1 0.0 2.0 1 1 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 Ribosomal_S7 PF00177.21 KXH37758.1 - 6e-25 87.6 0.0 1.1e-24 86.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Usp PF00582.26 KXH37759.1 - 2.4e-24 86.4 0.5 4.6e-15 56.4 0.3 2.7 2 0 0 2 2 2 2 Universal stress protein family CAP_N PF01213.19 KXH37760.1 - 0.5 9.8 1.6 1.1 8.7 1.6 1.5 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal OCD_Mu_crystall PF02423.15 KXH37761.1 - 1.3e-10 40.8 0.1 8e-06 25.0 0.1 2.8 3 0 0 3 3 3 2 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.20 KXH37761.1 - 0.11 12.6 0.0 5.6 7.0 0.0 2.7 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Cg6151-P PF10233.9 KXH37763.1 - 5.1e-41 139.5 16.1 6.1e-41 139.3 16.1 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P Aim21 PF11489.8 KXH37764.1 - 1.2e-182 609.6 83.5 1.2e-182 609.6 83.5 2.3 3 0 0 3 3 3 1 Altered inheritance of mitochondria protein 21 ApbA_C PF08546.11 KXH37839.1 - 3.1e-29 101.7 0.1 5.4e-29 100.9 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 KXH37839.1 - 2.6e-22 79.1 0.0 6.8e-22 77.7 0.0 1.7 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA DUF5345 PF17280.2 KXH37839.1 - 0.21 11.6 0.6 0.53 10.3 0.1 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5345) SNF2_N PF00176.23 KXH37840.1 - 4.1e-65 219.8 0.0 7.4e-65 218.9 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KXH37840.1 - 3.4e-18 66.0 0.0 1.1e-17 64.3 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXH37840.1 - 5.2e-10 39.6 0.0 3.4e-09 36.9 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UPF0242 PF06785.11 KXH37840.1 - 1.9 8.5 9.0 6.3 6.8 9.0 1.8 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Herpes_DNAp_acc PF04929.12 KXH37840.1 - 3.4 6.5 5.7 7.7 5.4 5.7 1.6 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Ribosomal_S11 PF00411.19 KXH37841.1 - 1.7e-46 157.2 1.1 2.1e-46 156.9 1.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 CBM_25 PF03423.13 KXH37841.1 - 0.089 13.1 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 Carbohydrate binding domain (family 25) Ribosomal_L30_N PF08079.12 KXH37842.1 - 1e-25 89.7 16.7 1.7e-25 89.1 16.7 1.3 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 KXH37842.1 - 2.7e-16 59.2 2.3 2.7e-16 59.2 2.3 2.0 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e DUF1943 PF09172.11 KXH37842.1 - 0.14 11.4 0.9 0.19 10.9 0.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) Fe-S_biosyn PF01521.20 KXH37843.1 - 2.7e-13 50.1 0.0 9.5e-12 45.1 0.0 2.2 1 1 0 1 1 1 1 Iron-sulphur cluster biosynthesis KH_7 PF17214.3 KXH37843.1 - 0.00074 19.4 0.0 0.0014 18.5 0.0 1.4 1 0 0 1 1 1 1 KH domain DUF3439 PF11921.8 KXH37843.1 - 0.81 9.7 6.3 1.4 8.9 6.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) RSN1_TM PF13967.6 KXH37844.1 - 0.091 12.5 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Late exocytosis, associated with Golgi transport TMEM132D_C PF15706.5 KXH37844.1 - 0.16 11.8 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term DUF4006 PF13179.6 KXH37844.1 - 0.2 11.6 0.0 0.36 10.8 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF4006) DUF543 PF04418.12 KXH37845.1 - 3.7e-30 103.7 0.0 4.3e-30 103.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) Urb2 PF10441.9 KXH37846.1 - 6.9e-67 225.3 1.8 3.2e-66 223.2 1.8 2.3 1 0 0 1 1 1 1 Urb2/Npa2 family partial_CstF PF15861.5 KXH37846.1 - 0.0086 15.8 0.3 0.28 11.0 0.0 3.1 2 0 0 2 2 2 1 Partial cleavage stimulation factor domain Fanconi_A_N PF15865.5 KXH37846.1 - 2.9 7.2 8.0 1.6 8.0 0.0 3.9 4 1 0 4 4 4 0 Fanconi anaemia group A protein N terminus PI3_PI4_kinase PF00454.27 KXH37847.1 - 8.5e-33 114.2 0.0 5.2e-32 111.6 0.0 2.0 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Pik1 PF11522.8 KXH37847.1 - 4.5e-19 68.2 0.0 8.7e-19 67.2 0.0 1.5 1 0 0 1 1 1 1 Yeast phosphatidylinositol-4-OH kinase Pik1 DUF4135 PF13575.6 KXH37847.1 - 0.034 13.5 0.0 0.067 12.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) CXCR4_N PF12109.8 KXH37847.1 - 0.093 13.0 0.1 0.24 11.7 0.1 1.6 1 0 0 1 1 1 0 CXCR4 Chemokine receptor N terminal PI3Ka PF00613.20 KXH37847.1 - 0.21 10.9 0.4 0.4 10.0 0.4 1.4 1 0 0 1 1 1 0 Phosphoinositide 3-kinase family, accessory domain (PIK domain) CBFD_NFYB_HMF PF00808.23 KXH37848.1 - 2e-12 47.2 3.1 3.1e-12 46.6 3.1 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIIA PF03153.13 KXH37848.1 - 0.00029 21.0 29.2 0.00037 20.6 29.2 1.0 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Histone PF00125.24 KXH37848.1 - 0.081 13.3 0.0 0.081 13.3 0.0 2.3 3 0 0 3 3 3 0 Core histone H2A/H2B/H3/H4 Say1_Mug180 PF10340.9 KXH37849.1 - 1.2e-19 70.5 0.0 2.2e-13 49.8 0.0 2.3 2 1 0 2 2 2 2 Steryl acetyl hydrolase Abhydrolase_3 PF07859.13 KXH37849.1 - 7.2e-18 65.2 0.0 1.2e-17 64.5 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KXH37849.1 - 0.0049 15.8 0.0 0.24 10.2 0.0 2.0 2 0 0 2 2 2 2 Carboxylesterase family mRNA_cap_enzyme PF01331.19 KXH37850.1 - 2.8e-58 197.0 0.7 4.9e-58 196.2 0.7 1.4 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 KXH37850.1 - 2.1e-31 108.8 0.0 3.8e-31 107.9 0.0 1.4 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.21 KXH37850.1 - 1.1e-11 44.8 0.1 3.9e-07 29.9 0.0 2.2 1 1 1 2 2 2 2 ATP dependent DNA ligase domain RNA_ligase PF09414.10 KXH37850.1 - 0.00012 22.4 0.0 0.00018 21.9 0.0 1.3 1 0 0 1 1 1 1 RNA ligase PX PF00787.24 KXH37851.1 - 1.7e-19 69.9 0.0 7.2e-19 67.8 0.0 2.1 2 0 0 2 2 2 1 PX domain Vps5 PF09325.10 KXH37851.1 - 3e-13 49.9 10.7 2.4e-08 33.8 0.3 2.1 2 0 0 2 2 2 2 Vps5 C terminal like TPR_1 PF00515.28 KXH37853.1 - 1.2e-30 104.0 18.1 0.00059 19.5 0.2 11.3 11 0 0 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.17 KXH37853.1 - 1.4e-26 90.4 32.0 0.002 18.1 0.3 12.3 13 0 0 13 13 12 8 Tetratricopeptide repeat TPR_8 PF13181.6 KXH37853.1 - 1e-22 78.4 23.8 0.0012 18.9 0.2 11.9 12 0 0 12 12 12 5 Tetratricopeptide repeat TPR_7 PF13176.6 KXH37853.1 - 1.2e-16 59.5 16.6 0.0011 18.8 0.1 9.9 10 0 0 10 10 9 4 Tetratricopeptide repeat TPR_12 PF13424.6 KXH37853.1 - 2e-13 50.4 31.2 0.0027 18.0 2.7 10.2 9 2 0 10 10 10 3 Tetratricopeptide repeat TPR_17 PF13431.6 KXH37853.1 - 1.1e-11 44.2 7.1 0.036 14.5 0.1 10.1 11 0 0 11 11 10 2 Tetratricopeptide repeat TPR_19 PF14559.6 KXH37853.1 - 4e-11 43.3 28.8 0.018 15.5 0.1 11.3 8 4 1 9 9 9 3 Tetratricopeptide repeat TPR_14 PF13428.6 KXH37853.1 - 9.6e-10 38.5 26.9 7 7.8 0.1 13.1 12 2 2 14 14 13 3 Tetratricopeptide repeat TPR_11 PF13414.6 KXH37853.1 - 3.7e-09 36.1 13.2 0.0069 16.0 0.0 6.9 7 0 0 7 7 7 3 TPR repeat TPR_16 PF13432.6 KXH37853.1 - 5.9e-07 30.0 21.9 0.17 12.6 0.0 8.8 8 2 2 10 10 10 3 Tetratricopeptide repeat TPR_10 PF13374.6 KXH37853.1 - 1e-06 28.4 13.5 0.017 15.0 0.0 8.2 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_6 PF13174.6 KXH37853.1 - 2.4e-06 27.8 19.2 1.7 9.5 0.0 11.3 13 1 0 13 13 13 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KXH37853.1 - 0.83 9.9 19.6 0.27 11.5 0.7 6.6 8 0 0 8 8 7 0 Anaphase-promoting complex, cyclosome, subunit 3 Alpha-amylase PF00128.24 KXH37854.1 - 4.6e-117 391.3 2.7 4.6e-117 391.3 2.7 1.5 2 0 0 2 2 2 1 Alpha amylase, catalytic domain DUF3459 PF11941.8 KXH37854.1 - 8e-05 22.9 0.0 0.00022 21.5 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3459) hDGE_amylase PF14701.6 KXH37854.1 - 0.013 14.6 0.1 0.023 13.8 0.1 1.3 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain Malt_amylase_C PF16657.5 KXH37854.1 - 0.021 15.0 0.0 0.055 13.6 0.0 1.7 1 0 0 1 1 1 0 Maltogenic Amylase, C-terminal domain Glyco_hydro_114 PF03537.13 KXH37854.1 - 0.087 12.1 0.1 0.22 10.8 0.1 1.6 1 0 0 1 1 1 0 Glycoside-hydrolase family GH114 CMAS PF02353.20 KXH37855.1 - 5.2e-24 85.0 0.0 3.1e-16 59.5 0.0 2.1 2 0 0 2 2 2 2 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 KXH37855.1 - 1.7e-05 24.7 0.1 7e-05 22.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Herpes_gE PF02480.16 KXH37856.1 - 0.098 11.4 0.0 0.13 11.0 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF4328 PF14219.6 KXH37856.1 - 0.12 12.0 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) Use1 PF09753.9 KXH37858.1 - 2e-11 44.1 2.0 1.3e-10 41.4 0.0 2.2 2 0 0 2 2 2 1 Membrane fusion protein Use1 DUF737 PF05300.11 KXH37858.1 - 0.057 13.8 4.8 0.13 12.6 4.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF737) GldM_N PF12081.8 KXH37858.1 - 0.099 12.7 0.5 0.21 11.7 0.5 1.5 1 0 0 1 1 1 0 GldM N-terminal domain Phage_Gp23 PF10669.9 KXH37858.1 - 0.93 9.8 6.5 4.3 7.7 0.1 3.1 2 2 1 3 3 3 0 Protein gp23 (Bacteriophage A118) RhoGAP PF00620.27 KXH37861.1 - 2.8e-39 134.4 0.0 4.8e-39 133.6 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain Mif2_N PF15624.6 KXH37862.1 - 1.3 9.7 7.0 0.4 11.4 0.4 2.7 3 1 0 3 3 3 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Chorion_2 PF03964.15 KXH37862.1 - 6.5 7.7 9.2 1.5 9.7 1.4 2.2 2 0 0 2 2 2 0 Chorion family 2 DUF4698 PF15769.5 KXH37930.1 - 1.1 8.2 6.8 1.2 8.1 6.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4698) Rad1 PF02144.16 KXH37931.1 - 1.6e-57 194.7 0.0 2e-57 194.4 0.0 1.0 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Bromodomain PF00439.25 KXH37932.1 - 1.8e-24 85.6 0.6 4e-24 84.5 0.6 1.6 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 KXH37932.1 - 6.3e-08 32.9 0.0 1.1e-07 32.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXH37932.1 - 5.5e-07 29.6 0.3 1.7e-06 28.0 0.1 1.8 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXH37932.1 - 0.00032 21.1 0.4 0.00061 20.2 0.1 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXH37932.1 - 0.097 12.7 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_3 PF13302.7 KXH37932.1 - 0.11 13.2 0.0 5.3 7.7 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain DUF1656 PF07869.12 KXH37933.1 - 0.11 12.6 2.8 0.18 11.8 2.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1656) DUF726 PF05277.12 KXH37934.1 - 3.4e-121 404.3 0.2 4.6e-121 403.9 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Thioesterase PF00975.20 KXH37934.1 - 0.00086 19.5 0.0 0.0017 18.5 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.7 KXH37934.1 - 0.043 14.4 0.1 0.13 12.8 0.1 1.8 1 0 0 1 1 1 0 Alpha/beta hydrolase family PE-PPE PF08237.11 KXH37934.1 - 0.064 12.8 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 PE-PPE domain Noc2 PF03715.13 KXH37935.1 - 6.4e-128 426.2 0.3 6.4e-128 426.2 0.3 2.0 2 0 0 2 2 2 1 Noc2p family Nop14 PF04147.12 KXH37935.1 - 0.00017 20.0 0.8 0.00017 20.0 0.8 4.1 2 2 1 3 3 3 1 Nop14-like family VPS28 PF03997.12 KXH37936.1 - 1.6e-68 230.1 0.2 1.9e-68 229.9 0.2 1.0 1 0 0 1 1 1 1 VPS28 protein MMM1 PF10296.9 KXH37937.1 - 6e-06 25.5 0.0 1.5e-05 24.3 0.0 1.6 2 0 0 2 2 2 1 Maintenance of mitochondrial morphology protein 1 PIP5K PF01504.18 KXH37938.1 - 7.7e-31 107.3 0.0 3.1e-22 79.1 0.0 2.6 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.24 KXH37938.1 - 1.2e-25 90.1 0.0 1.9e-25 89.5 0.0 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.21 KXH37938.1 - 1.4e-13 50.8 10.9 3.7e-13 49.4 10.9 1.8 1 0 0 1 1 1 1 FYVE zinc finger GPAT_N PF14829.6 KXH37938.1 - 0.17 11.9 0.1 0.51 10.4 0.1 1.8 1 0 0 1 1 1 0 Glycerol-3-phosphate acyltransferase N-terminal FYVE_2 PF02318.16 KXH37938.1 - 0.57 10.4 5.4 1.7 8.9 5.4 1.8 1 0 0 1 1 1 0 FYVE-type zinc finger Fmp27 PF10344.9 KXH37939.1 - 0.34 9.0 0.5 0.49 8.4 0.5 1.1 1 0 0 1 1 1 0 Mitochondrial protein from FMP27 BolA PF01722.18 KXH37940.1 - 3e-29 101.1 1.9 4.2e-29 100.6 1.9 1.2 1 0 0 1 1 1 1 BolA-like protein FANCI_HD1 PF14679.6 KXH37946.1 - 0.019 14.9 0.1 0.031 14.2 0.1 1.4 1 0 0 1 1 1 0 FANCI helical domain 1 Sec7 PF01369.20 KXH37947.1 - 8.7e-74 247.2 5.5 4.4e-73 244.9 0.8 3.1 3 0 0 3 3 3 1 Sec7 domain Sec7_N PF12783.7 KXH37947.1 - 1.9e-39 135.1 3.1 1.9e-39 135.1 3.1 3.1 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 KXH37947.1 - 5.4e-34 115.9 10.2 3e-32 110.3 0.1 5.4 5 0 0 5 5 5 2 Domain of unknown function (DUF1981) DCB PF16213.5 KXH37947.1 - 2.4e-23 82.7 3.1 1.9e-22 79.8 0.2 3.2 3 0 0 3 3 3 1 Dimerisation and cyclophilin-binding domain of Mon2 DREPP PF05558.12 KXH37947.1 - 1.1 9.1 5.3 3.3 7.6 5.3 1.8 1 0 0 1 1 1 0 DREPP plasma membrane polypeptide 2-oxoacid_dh PF00198.23 KXH37948.1 - 2.3e-73 246.5 0.0 3e-73 246.1 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KXH37948.1 - 1.2e-18 66.7 0.5 3.3e-18 65.3 0.5 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 KXH37948.1 - 2.8e-10 40.4 1.7 8.9e-10 38.7 1.7 1.9 1 0 0 1 1 1 1 e3 binding domain Fungal_trans PF04082.18 KXH37950.1 - 9e-14 51.1 0.1 1.4e-13 50.5 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH37950.1 - 2.9e-08 33.7 12.3 2.9e-08 33.7 12.3 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DASH_Hsk3 PF08227.11 KXH37950.1 - 0.032 14.6 1.2 1.1 9.7 0.3 2.6 2 0 0 2 2 2 0 DASH complex subunit Hsk3 like NAD_binding_10 PF13460.6 KXH37951.1 - 2.2e-05 24.4 0.0 2.9e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KXH37951.1 - 0.017 14.3 0.0 0.042 13.0 0.0 1.6 2 0 0 2 2 2 0 Male sterility protein Epimerase PF01370.21 KXH37951.1 - 0.14 11.6 0.0 0.2 11.1 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Methyltransf_23 PF13489.6 KXH37953.1 - 7.2e-29 100.7 0.0 3.6e-19 69.2 0.0 3.8 3 1 1 4 4 4 2 Methyltransferase domain Methyltransf_25 PF13649.6 KXH37953.1 - 5.2e-17 62.3 0.0 2.3e-09 37.8 0.0 2.8 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 KXH37953.1 - 7.7e-13 48.5 0.0 6e-07 29.4 0.0 3.0 2 2 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 KXH37953.1 - 7.1e-12 45.9 0.0 8.3e-06 26.5 0.0 2.7 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 KXH37953.1 - 1.2e-09 38.6 0.0 2.3e-05 25.0 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_4 PF02390.17 KXH37953.1 - 1.2e-05 24.8 0.0 0.043 13.3 0.0 2.5 2 0 0 2 2 2 2 Putative methyltransferase MTS PF05175.14 KXH37953.1 - 2e-05 24.2 0.0 0.16 11.5 0.0 2.8 3 0 0 3 3 3 2 Methyltransferase small domain PrmA PF06325.13 KXH37953.1 - 7e-05 22.4 0.0 0.31 10.4 0.0 2.9 3 0 0 3 3 3 2 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.19 KXH37953.1 - 0.00025 20.9 0.0 0.29 10.9 0.0 2.8 2 1 0 2 2 2 2 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.9 KXH37953.1 - 0.0005 19.9 0.0 0.79 9.4 0.0 2.3 2 0 0 2 2 2 2 Lysine methyltransferase FtsJ PF01728.19 KXH37953.1 - 0.00057 20.0 0.0 0.3 11.2 0.0 2.3 2 0 0 2 2 2 2 FtsJ-like methyltransferase Ubie_methyltran PF01209.18 KXH37953.1 - 0.00059 19.3 0.0 2.4 7.4 0.0 3.1 3 0 0 3 3 3 2 ubiE/COQ5 methyltransferase family Met_10 PF02475.16 KXH37953.1 - 0.0022 17.8 0.0 1.9 8.2 0.0 2.7 3 0 0 3 3 3 2 Met-10+ like-protein CopK PF11525.8 KXH37953.1 - 0.012 15.3 0.1 1.1 9.0 0.0 2.4 2 0 0 2 2 2 0 Copper resistance protein K Methyltransf_17 PF12692.7 KXH37953.1 - 0.016 15.2 0.0 4.7 7.2 0.0 3.0 2 1 0 2 2 2 0 S-adenosyl-L-methionine methyltransferase DUF4357 PF14267.6 KXH37953.1 - 0.042 13.8 0.0 7.5 6.6 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4357) Methyltransf_2 PF00891.18 KXH37953.1 - 0.088 12.1 0.3 2.3 7.5 0.0 3.0 4 0 0 4 4 4 0 O-methyltransferase domain DUF938 PF06080.12 KXH37953.1 - 0.13 12.0 0.0 16 5.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF938) GidB PF02527.15 KXH37953.1 - 0.14 11.4 0.1 19 4.5 0.0 2.6 3 0 0 3 3 3 0 rRNA small subunit methyltransferase G HI0933_like PF03486.14 KXH37954.1 - 1.2e-06 27.5 0.0 1.6e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.19 KXH37954.1 - 1.3e-06 27.9 0.1 1.8e-06 27.4 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 KXH37954.1 - 1.6e-06 27.5 0.0 1.6e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KXH37954.1 - 1e-05 25.7 0.0 2.7e-05 24.3 0.0 1.8 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KXH37954.1 - 6.2e-05 22.4 0.0 6.8e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXH37954.1 - 8.8e-05 22.2 0.0 9.4e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXH37954.1 - 0.0001 21.7 0.0 0.0001 21.7 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KXH37954.1 - 0.0012 17.8 0.0 0.0014 17.6 0.0 1.1 1 0 0 1 1 1 1 Tryptophan halogenase FAD_oxidored PF12831.7 KXH37954.1 - 0.0016 17.9 0.0 0.0022 17.4 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 KXH37954.1 - 0.0051 17.2 0.0 0.0053 17.2 0.0 1.2 1 0 0 1 1 1 1 Putative NAD(P)-binding GIDA PF01134.22 KXH37954.1 - 0.018 14.2 0.1 0.022 13.9 0.1 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox PF00070.27 KXH37954.1 - 0.026 15.1 0.0 0.039 14.5 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KXH37954.1 - 0.03 13.4 0.0 0.03 13.4 0.0 1.1 1 0 0 1 1 1 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 KXH37954.1 - 0.11 11.8 0.0 0.12 11.6 0.0 1.1 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Glu_dehyd_C PF16912.5 KXH37954.1 - 0.21 11.0 0.0 0.27 10.7 0.0 1.1 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus FAD_binding_3 PF01494.19 KXH37955.1 - 0.00026 20.4 0.1 0.018 14.3 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 KXH37955.1 - 0.033 13.8 0.0 0.042 13.4 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXH37955.1 - 0.048 12.9 0.1 0.077 12.2 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase adh_short PF00106.25 KXH37956.1 - 4.1e-35 121.0 1.2 1.2e-21 77.1 0.1 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXH37956.1 - 2.9e-33 115.4 0.1 5.3e-19 68.7 0.0 2.3 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH37956.1 - 1e-10 41.8 0.1 2.6e-10 40.5 0.1 1.7 1 0 0 1 1 1 1 KR domain Imm74 PF15603.6 KXH37956.1 - 0.0029 17.8 0.0 0.025 14.8 0.0 2.3 2 0 0 2 2 2 1 Immunity protein 74 Epimerase PF01370.21 KXH37956.1 - 0.0085 15.6 0.1 0.1 12.0 0.1 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXH37956.1 - 0.056 12.4 0.0 0.092 11.7 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KXH37956.1 - 0.069 12.3 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Shikimate_DH PF01488.20 KXH37956.1 - 0.15 12.1 0.1 0.28 11.2 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Metallophos PF00149.28 KXH37957.1 - 5.2e-08 33.6 0.9 7.8e-08 33.1 0.9 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Endopep_inhib PF16800.5 KXH37957.1 - 0.038 13.9 0.0 0.066 13.2 0.0 1.3 1 0 0 1 1 1 0 IseA DL-endopeptidase inhibitor Sugar_tr PF00083.24 KXH37958.1 - 4.6e-120 401.5 23.2 5.5e-120 401.3 23.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH37958.1 - 2.2e-18 66.3 46.7 3.7e-12 45.8 16.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2530 PF10745.9 KXH37958.1 - 0.06 13.6 0.7 0.06 13.6 0.7 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2530) Acetyltransf_10 PF13673.7 KXH37959.1 - 4.9e-10 39.4 0.0 9.2e-10 38.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXH37959.1 - 7.8e-09 35.8 0.0 1.3e-08 35.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXH37959.1 - 2.2e-07 31.2 0.0 3.8e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KXH37959.1 - 4.7e-05 23.4 0.0 0.00012 22.1 0.0 1.6 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 KXH37959.1 - 0.00084 19.4 0.0 0.028 14.5 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXH37959.1 - 0.009 16.0 0.0 0.019 14.9 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_15 PF17013.5 KXH37959.1 - 0.12 11.8 0.0 0.29 10.6 0.0 1.6 1 1 0 1 1 1 0 Putative acetyl-transferase DUF2551 PF10826.8 KXH37960.1 - 0.068 13.4 0.0 0.18 12.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2551) CBM_1 PF00734.18 KXH37961.1 - 5.5e-11 42.2 9.6 5.5e-11 42.2 9.6 2.3 2 0 0 2 2 2 1 Fungal cellulose binding domain Pec_lyase_C PF00544.19 KXH37961.1 - 1.2e-10 41.3 6.0 4e-09 36.4 6.0 2.2 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 KXH37961.1 - 0.00023 21.1 6.3 0.00076 19.4 6.4 1.8 1 1 0 1 1 1 1 Right handed beta helix region Hamartin PF04388.12 KXH37961.1 - 0.46 9.1 1.6 0.6 8.7 1.6 1.1 1 0 0 1 1 1 0 Hamartin protein MFS_1 PF07690.16 KXH37962.1 - 5.6e-22 78.1 37.1 2.3e-21 76.1 30.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily 2-Hacid_dh_C PF02826.19 KXH37963.1 - 5.4e-42 143.2 0.0 1.8e-27 95.9 0.0 2.2 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 KXH37963.1 - 0.095 12.6 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Acetyltransf_1 PF00583.25 KXH37964.1 - 6.6e-14 52.2 0.1 1.2e-13 51.3 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 KXH37964.1 - 5.2e-07 29.6 0.0 8.6e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 KXH37964.1 - 4.7e-06 26.9 0.1 6.8e-06 26.4 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KXH37964.1 - 4.6e-05 23.3 0.0 6.3e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KXH37964.1 - 0.063 14.0 0.0 0.083 13.6 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KXH37964.1 - 0.083 13.0 0.0 0.34 11.0 0.0 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Smg4_UPF3 PF03467.15 KXH37964.1 - 0.16 12.0 0.0 0.22 11.5 0.0 1.1 1 0 0 1 1 1 0 Smg-4/UPF3 family PanZ PF12568.8 KXH37964.1 - 0.16 11.7 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ Ank_4 PF13637.6 KXH37966.1 - 3.1e-13 49.9 0.1 4.2e-07 30.4 0.1 3.8 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXH37966.1 - 5.5e-09 36.5 0.0 0.006 17.2 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXH37966.1 - 8e-08 32.0 1.5 0.021 15.3 0.0 4.6 4 1 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 KXH37966.1 - 3.7e-07 30.3 0.7 0.25 11.8 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 KXH37966.1 - 7.5e-06 26.1 0.2 0.013 15.8 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeats (many copies) KilA-N PF04383.13 KXH37966.1 - 5e-05 23.1 0.2 0.0004 20.2 0.2 2.3 1 1 0 1 1 1 1 KilA-N domain OmpH PF03938.14 KXH37966.1 - 0.073 13.4 2.9 1.1 9.6 2.9 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) USP8_interact PF08941.10 KXH37966.1 - 0.15 11.9 3.0 0.26 11.1 3.0 1.4 1 0 0 1 1 1 0 USP8 interacting FYVE PF01363.21 KXH37967.1 - 5.8e-25 87.2 20.3 1.1e-17 64.0 3.5 3.0 3 0 0 3 3 3 2 FYVE zinc finger Rbsn PF11464.8 KXH37967.1 - 4.3e-18 64.7 3.6 9.9e-18 63.6 3.6 1.7 1 0 0 1 1 1 1 Rabenosyn Rab binding domain zf-Di19 PF05605.12 KXH37967.1 - 0.00017 21.8 6.0 0.016 15.4 0.1 2.9 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-AN1 PF01428.16 KXH37967.1 - 0.00038 20.5 1.6 0.00038 20.5 1.6 4.0 3 1 1 4 4 4 1 AN1-like Zinc finger zf-C2H2_2 PF12756.7 KXH37967.1 - 0.014 15.8 1.6 1.2 9.5 0.0 2.9 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Siva PF05458.12 KXH37967.1 - 0.21 11.2 7.6 1.2 8.8 0.3 2.9 2 1 0 2 2 2 0 Cd27 binding protein (Siva) Tropomyosin PF00261.20 KXH37967.1 - 0.3 10.4 19.0 0.42 9.9 0.2 2.9 3 0 0 3 3 3 0 Tropomyosin zf-C2H2_9 PF16293.5 KXH37967.1 - 0.3 10.9 2.2 9.5 6.2 0.0 2.8 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) HypA PF01155.19 KXH37967.1 - 1.2 9.2 12.7 0.6 10.1 0.7 3.8 3 1 1 4 4 4 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-ribbon_3 PF13248.6 KXH37967.1 - 5.1 6.7 15.8 6.9 6.2 2.3 4.8 5 0 0 5 5 5 0 zinc-ribbon domain NAD_binding_7 PF13241.6 KXH37968.1 - 1.6e-30 105.6 0.0 2.6e-30 104.9 0.0 1.3 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 KXH37968.1 - 1.4e-26 91.9 0.1 2.2e-26 91.3 0.1 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.6 KXH37968.1 - 2.5e-16 58.8 0.2 4.1e-16 58.1 0.2 1.4 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Pyr_redox_3 PF13738.6 KXH37968.1 - 0.0007 18.9 0.0 0.00099 18.4 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Dynamin_M PF01031.20 KXH37968.1 - 0.068 12.4 0.0 0.093 11.9 0.0 1.1 1 0 0 1 1 1 0 Dynamin central region TrkA_N PF02254.18 KXH37968.1 - 0.17 12.1 0.1 0.34 11.2 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain CENP-L PF13092.6 KXH37969.1 - 1.5e-55 187.9 0.0 2.8e-55 187.0 0.0 1.4 2 0 0 2 2 2 1 Kinetochore complex Sim4 subunit Fta1 Glyco_hydro_10 PF00331.20 KXH37970.1 - 1.3e-106 356.3 0.8 1.5e-106 356.1 0.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Beta-prism_lec PF16458.5 KXH37970.1 - 0.02 14.9 0.4 0.094 12.7 0.3 2.0 2 0 0 2 2 2 0 Beta-prism lectin Thioesterase PF00975.20 KXH37971.1 - 2.5e-21 76.9 0.0 4.7e-21 76.0 0.0 1.6 1 0 0 1 1 1 1 Thioesterase domain AMP-binding PF00501.28 KXH37971.1 - 3.3e-21 75.4 0.0 5e-21 74.8 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Abhydrolase_6 PF12697.7 KXH37971.1 - 4.7e-05 24.1 0.4 8.5e-05 23.2 0.4 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Tcp11 PF05794.13 KXH37971.1 - 0.012 14.8 0.1 0.018 14.2 0.1 1.2 1 0 0 1 1 1 0 T-complex protein 11 Hydrolase_4 PF12146.8 KXH37971.1 - 0.11 11.8 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Esterase_phd PF10503.9 KXH37972.1 - 7.4e-22 77.9 0.2 1e-21 77.5 0.2 1.1 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 KXH37972.1 - 2e-08 33.9 1.2 2.8e-08 33.5 1.2 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S10 PF00450.22 KXH37972.1 - 0.0011 18.5 0.1 0.0019 17.7 0.1 1.3 1 0 0 1 1 1 1 Serine carboxypeptidase COesterase PF00135.28 KXH37972.1 - 0.0065 15.4 1.3 0.028 13.3 1.3 1.8 1 1 0 1 1 1 1 Carboxylesterase family Esterase PF00756.20 KXH37972.1 - 0.0095 15.6 0.5 0.014 15.1 0.5 1.3 1 0 0 1 1 1 1 Putative esterase BAAT_C PF08840.11 KXH37972.1 - 0.041 13.8 0.2 0.067 13.1 0.2 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_3 PF07859.13 KXH37972.1 - 0.1 12.5 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Fungal_trans PF04082.18 KXH37973.1 - 1.9e-27 96.0 0.1 2.7e-27 95.4 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH37973.1 - 1.6e-06 28.2 8.8 3.5e-06 27.0 8.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Vps53_N PF04100.12 KXH37980.1 - 4.2e-105 351.8 0.3 7.4e-105 351.0 0.3 1.3 1 0 0 1 1 1 1 Vps53-like, N-terminal Vps54_N PF10475.9 KXH37980.1 - 1.2e-06 28.1 3.0 2.2e-06 27.2 3.0 1.3 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex DUF2451 PF10474.9 KXH37980.1 - 0.00045 20.1 0.0 0.00098 19.0 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) RINT1_TIP1 PF04437.13 KXH37980.1 - 0.003 16.5 0.9 0.16 10.8 0.0 3.0 3 0 0 3 3 3 1 RINT-1 / TIP-1 family Zw10 PF06248.13 KXH37980.1 - 0.0071 15.0 3.2 0.015 13.9 3.2 1.5 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 VPS53_C PF16854.5 KXH37980.1 - 0.012 15.4 0.0 0.051 13.5 0.0 1.9 1 1 1 2 2 2 0 Vacuolar protein sorting-associated protein 53 C-terminus DUF5082 PF16888.5 KXH37980.1 - 0.026 14.8 2.1 0.36 11.1 0.7 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) Spc7 PF08317.11 KXH37980.1 - 0.053 12.4 2.2 0.1 11.5 2.2 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein UPF0175 PF03683.13 KXH37980.1 - 0.085 12.6 0.0 0.43 10.3 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0175) DUF1664 PF07889.12 KXH37980.1 - 0.13 12.3 0.5 0.42 10.7 0.5 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF3037 PF11236.8 KXH37980.1 - 0.15 12.5 0.1 1.2 9.6 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3037) Trp_repressor PF01371.19 KXH37980.1 - 0.31 11.2 2.9 13 6.0 1.3 2.8 2 0 0 2 2 2 0 Trp repressor protein DUF1776 PF08643.10 KXH37981.1 - 6.8e-106 354.0 0.0 8.6e-106 353.6 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) adh_short PF00106.25 KXH37981.1 - 0.037 13.5 0.0 0.13 11.7 0.0 1.8 2 0 0 2 2 2 0 short chain dehydrogenase MFS_1 PF07690.16 KXH37982.1 - 6.5e-19 68.1 55.9 1.1e-11 44.3 27.0 3.3 2 1 2 4 4 4 2 Major Facilitator Superfamily TRI12 PF06609.13 KXH37982.1 - 2.6e-08 32.8 19.7 3.9e-08 32.2 19.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Pox_A14 PF05767.12 KXH37982.1 - 0.093 12.9 0.9 0.48 10.6 0.9 2.2 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 DUF1689 PF07954.11 KXH37982.1 - 0.15 12.4 0.3 0.48 10.8 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1689) Helo_like_N PF17111.5 KXH38111.1 - 2.2e-74 249.4 7.6 1.9e-71 239.8 0.7 2.3 2 0 0 2 2 2 2 Fungal N-terminal domain of STAND proteins Suppressor_APC PF11414.8 KXH38111.1 - 0.043 13.9 0.3 0.47 10.5 0.0 2.6 2 0 0 2 2 2 0 Adenomatous polyposis coli tumour suppressor protein DUF4455 PF14643.6 KXH38111.1 - 0.089 11.4 2.9 0.18 10.4 2.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4455) CorA PF01544.18 KXH38111.1 - 1.3 8.3 8.0 0.23 10.7 0.7 2.6 2 1 1 3 3 3 0 CorA-like Mg2+ transporter protein CLZ PF16526.5 KXH38111.1 - 3.2 8.2 5.8 8.6 6.8 0.4 3.3 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels TBCA PF02970.16 KXH38111.1 - 3.8 7.9 6.9 4.3 7.7 0.0 3.4 3 1 1 4 4 4 0 Tubulin binding cofactor A FAD_binding_1 PF00667.20 KXH38112.1 - 1e-44 152.8 0.0 1.4e-44 152.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 KXH38112.1 - 3.4e-09 37.3 0.0 1e-08 35.8 0.0 1.9 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain zf-RING_2 PF13639.6 KXH38113.1 - 2.3e-11 43.8 3.9 4.5e-11 42.9 3.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KXH38113.1 - 6e-10 39.3 2.8 1.4e-09 38.1 2.8 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KXH38113.1 - 4.3e-07 29.9 0.4 8.9e-07 28.9 0.4 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 KXH38113.1 - 4.6e-06 26.4 5.7 1.5e-05 24.7 5.7 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXH38113.1 - 1.6e-05 24.7 2.8 2.7e-05 24.0 2.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KXH38113.1 - 6.6e-05 22.7 3.2 0.00011 22.0 3.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KXH38113.1 - 6.7e-05 22.7 2.3 0.00015 21.6 2.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KXH38113.1 - 0.00029 20.6 3.2 0.00056 19.7 3.2 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KXH38113.1 - 0.0012 18.9 4.6 0.0025 17.8 4.6 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_11 PF17123.5 KXH38113.1 - 0.0022 17.7 0.7 0.0058 16.3 0.7 1.7 1 1 0 1 1 1 1 RING-like zinc finger FANCL_C PF11793.8 KXH38113.1 - 0.0091 16.2 4.1 0.15 12.2 4.1 2.3 1 1 0 1 1 1 1 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 KXH38113.1 - 0.072 12.7 5.6 0.16 11.6 5.6 1.6 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-Nse PF11789.8 KXH38113.1 - 0.37 10.6 2.1 0.87 9.5 2.1 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.6 KXH38113.1 - 2.9 8.1 4.7 0.52 10.5 1.1 1.6 2 0 0 2 2 1 0 zinc finger of C3HC4-type, RING Cullin PF00888.22 KXH38115.1 - 2.3e-23 82.7 0.0 5.1e-23 81.6 0.0 1.4 1 0 0 1 1 1 1 Cullin family ANAPC2 PF08672.11 KXH38115.1 - 3.6e-20 72.2 0.8 1.5e-19 70.2 0.3 2.5 2 0 0 2 2 2 1 Anaphase promoting complex (APC) subunit 2 Malate_DH PF12434.8 KXH38116.1 - 0.32 11.1 1.4 1.2 9.3 0.5 2.2 2 0 0 2 2 2 0 Malate dehydrogenase enzyme FAD_binding_3 PF01494.19 KXH38117.1 - 5.4e-75 252.8 0.0 2.1e-55 188.4 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Phe_hydrox_dim PF07976.12 KXH38117.1 - 4.8e-48 163.3 0.0 8.5e-48 162.5 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain DAO PF01266.24 KXH38117.1 - 3.9e-05 23.4 0.2 0.00097 18.8 0.3 2.8 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXH38117.1 - 0.00012 21.4 0.1 0.0002 20.7 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXH38117.1 - 0.00027 19.7 0.0 0.00042 19.1 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 KXH38117.1 - 0.0003 20.0 0.1 0.00046 19.4 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KXH38117.1 - 0.0018 18.4 0.1 0.005 17.0 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KXH38117.1 - 0.0042 16.4 0.0 0.0085 15.4 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KXH38117.1 - 0.0042 16.2 0.0 0.0061 15.7 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 KXH38117.1 - 0.0045 16.3 0.0 0.013 14.8 0.0 1.7 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.22 KXH38117.1 - 0.0074 15.4 0.2 0.021 13.9 0.0 1.7 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox PF00070.27 KXH38117.1 - 0.0097 16.4 0.0 0.022 15.3 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KXH38117.1 - 0.016 14.5 0.0 0.029 13.7 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 KXH38117.1 - 0.028 13.8 0.1 0.05 13.0 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase FixH PF05751.11 KXH38117.1 - 0.12 12.3 0.0 0.45 10.5 0.0 1.9 2 0 0 2 2 2 0 FixH CLP1_P PF16575.5 KXH38118.1 - 4.5e-29 101.6 0.0 6.7e-29 101.0 0.0 1.3 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop RNA_polI_A34 PF08208.11 KXH38119.1 - 2.5e-45 155.1 7.5 2.5e-45 155.1 7.5 6.5 3 2 0 3 3 3 1 DNA-directed RNA polymerase I subunit RPA34.5 DUF629 PF04780.12 KXH38120.1 - 0.041 12.4 0.1 0.057 11.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF629) SDA1 PF05285.12 KXH38122.1 - 3.2 7.1 8.2 4.8 6.5 8.2 1.2 1 0 0 1 1 1 0 SDA1 FUSC-like PF12805.7 KXH38122.1 - 4.2 6.4 5.2 12 4.9 2.7 2.1 1 1 0 2 2 2 0 FUSC-like inner membrane protein yccS PAP2_3 PF14378.6 KXH38123.1 - 4.9e-25 88.3 11.1 4.9e-25 88.3 11.1 1.7 2 0 0 2 2 2 1 PAP2 superfamily PAP2 PF01569.21 KXH38123.1 - 8.5e-10 38.5 5.6 8.5e-10 38.5 5.6 2.2 2 1 0 2 2 2 1 PAP2 superfamily Peptidase_M3 PF01432.20 KXH38125.1 - 5e-105 352.4 0.0 5.2e-93 312.8 0.0 2.1 2 0 0 2 2 2 2 Peptidase family M3 MFS_1 PF07690.16 KXH38191.1 - 3.6e-24 85.4 18.8 3.6e-24 85.4 18.8 1.4 1 1 1 2 2 2 2 Major Facilitator Superfamily DEAD PF00270.29 KXH38192.1 - 3e-22 79.2 0.1 1.8e-21 76.7 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXH38192.1 - 7.1e-21 74.6 0.0 2e-16 60.3 0.0 3.2 2 0 0 2 2 2 2 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 KXH38192.1 - 5.2e-18 65.5 7.5 2e-17 63.6 7.5 2.2 1 0 0 1 1 1 1 RecQ zinc-binding RQC PF09382.10 KXH38192.1 - 6.1e-14 51.8 0.0 1.5e-13 50.5 0.0 1.7 1 0 0 1 1 1 1 RQC domain ResIII PF04851.15 KXH38192.1 - 4.8e-08 33.2 0.1 1.8e-07 31.3 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HRDC PF00570.23 KXH38192.1 - 0.0014 18.6 0.0 0.0039 17.1 0.0 1.8 1 0 0 1 1 1 1 HRDC domain HSBP1 PF06825.12 KXH38192.1 - 0.042 13.7 0.8 1.6 8.7 0.2 2.6 2 0 0 2 2 2 0 Heat shock factor binding protein 1 SecA_DEAD PF07517.14 KXH38192.1 - 0.13 11.5 1.4 0.54 9.5 0.0 2.3 2 0 0 2 2 2 0 SecA DEAD-like domain KAR9 PF08580.10 KXH38193.1 - 3.9e-182 607.4 3.0 3.9e-182 607.4 3.0 2.7 2 1 0 2 2 2 1 Yeast cortical protein KAR9 Syntaxin-6_N PF09177.11 KXH38193.1 - 0.025 15.1 3.8 2 9.0 0.0 4.2 3 1 0 4 4 4 0 Syntaxin 6, N-terminal UvrA_inter PF17760.1 KXH38193.1 - 0.14 12.3 1.5 0.41 10.8 0.7 2.0 2 0 0 2 2 2 0 UvrA interaction domain HetR_C PF18460.1 KXH38193.1 - 0.21 11.5 2.5 0.88 9.5 0.1 2.7 2 0 0 2 2 2 0 Heterocyst differentiation regulator C-terminal Hood domain DUF4795 PF16043.5 KXH38193.1 - 6.8 6.2 7.5 31 4.1 1.3 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4795) AAA PF00004.29 KXH38195.1 - 2.6e-42 144.4 0.0 4.3e-42 143.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KXH38195.1 - 1.2e-11 44.4 0.1 1.2e-10 41.2 0.1 2.2 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 KXH38195.1 - 5.7e-10 38.9 0.1 1e-09 38.0 0.1 1.4 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KXH38195.1 - 1.7e-07 31.7 0.1 8.5e-05 23.0 0.1 2.9 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 KXH38195.1 - 3.3e-06 27.1 0.1 5.3e-05 23.2 0.1 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KXH38195.1 - 4.1e-06 27.0 0.0 1.3e-05 25.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 KXH38195.1 - 9.5e-06 25.4 0.0 2e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KXH38195.1 - 0.00034 20.9 0.1 0.0047 17.2 0.1 2.4 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 KXH38195.1 - 0.00049 19.3 0.0 0.001 18.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 KXH38195.1 - 0.00065 20.3 0.1 0.0031 18.1 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KXH38195.1 - 0.0015 18.0 0.0 0.0031 17.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region TIP49 PF06068.13 KXH38195.1 - 0.003 16.8 0.0 0.0055 16.0 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain Mg_chelatase PF01078.21 KXH38195.1 - 0.0048 16.3 0.0 0.0097 15.3 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TsaE PF02367.17 KXH38195.1 - 0.005 16.8 0.0 0.012 15.6 0.0 1.6 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 KXH38195.1 - 0.0056 16.9 0.0 0.012 15.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KXH38195.1 - 0.007 16.1 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.22 KXH38195.1 - 0.0072 16.7 0.0 0.015 15.7 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_14 PF13173.6 KXH38195.1 - 0.0087 16.1 0.0 0.022 14.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KXH38195.1 - 0.0099 15.7 0.1 0.33 10.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 KXH38195.1 - 0.012 15.3 0.0 0.036 13.8 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_3 PF07726.11 KXH38195.1 - 0.017 15.0 0.0 0.038 13.8 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KXH38195.1 - 0.026 14.2 0.0 0.076 12.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain eIF-1a PF01176.19 KXH38195.1 - 0.032 14.0 0.1 0.062 13.1 0.1 1.4 1 0 0 1 1 1 0 Translation initiation factor 1A / IF-1 DUF4200 PF13863.6 KXH38195.1 - 0.034 14.5 0.8 0.034 14.5 0.8 1.8 2 0 0 2 2 1 0 Domain of unknown function (DUF4200) Prot_ATP_OB_N PF17758.1 KXH38195.1 - 0.037 13.7 0.0 0.098 12.3 0.0 1.6 1 0 0 1 1 1 0 Proteasomal ATPase OB N-terminal domain ATPase PF06745.13 KXH38195.1 - 0.048 13.0 0.2 0.17 11.2 0.0 2.0 3 0 0 3 3 3 0 KaiC AAA_30 PF13604.6 KXH38195.1 - 0.051 13.3 0.0 0.14 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KXH38195.1 - 0.056 13.4 0.1 0.18 11.7 0.0 1.9 2 0 0 2 2 1 0 NACHT domain AAA_28 PF13521.6 KXH38195.1 - 0.064 13.5 0.0 0.22 11.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 KXH38195.1 - 0.082 12.4 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 KXH38195.1 - 0.12 11.9 0.0 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 KXH38195.1 - 0.16 11.1 0.0 0.27 10.3 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_23 PF13476.6 KXH38195.1 - 1.2 9.6 4.5 17 5.9 0.9 2.6 2 1 0 2 2 2 0 AAA domain SIS PF01380.22 KXH38196.1 - 1.9e-58 196.0 0.2 9.8e-32 109.6 0.1 2.3 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 KXH38196.1 - 1.5e-17 64.0 0.0 3.2e-17 63.0 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 KXH38196.1 - 1.2e-10 41.4 0.0 2.9e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 KXH38196.1 - 0.00099 18.1 0.0 0.0016 17.4 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II CAP18_C PF12153.8 KXH38196.1 - 0.078 12.9 0.3 0.18 11.7 0.3 1.5 1 0 0 1 1 1 0 LPS binding domain of CAP18 (C terminal) PTSIIB_sorb PF03830.15 KXH38196.1 - 0.13 12.4 0.0 0.48 10.6 0.0 1.9 1 0 0 1 1 1 0 PTS system sorbose subfamily IIB component Endosulfine PF04667.17 KXH38196.1 - 0.17 12.1 0.1 0.44 10.7 0.1 1.7 1 0 0 1 1 1 0 cAMP-regulated phosphoprotein/endosulfine conserved region Proteasome PF00227.26 KXH38197.1 - 1.1e-28 100.0 0.0 1.3e-28 99.8 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit HMG_box_2 PF09011.10 KXH38198.1 - 2.3e-09 37.7 0.3 2.3e-09 37.7 0.3 3.2 4 0 0 4 4 4 2 HMG-box domain HMG_box PF00505.19 KXH38198.1 - 8e-08 32.6 0.6 8e-08 32.6 0.6 3.1 3 0 0 3 3 3 2 HMG (high mobility group) box Dicty_REP PF05086.12 KXH38198.1 - 5.6 4.8 5.3 6 4.7 5.3 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Med3 PF11593.8 KXH38198.1 - 7.3 5.7 13.4 8.6 5.4 13.4 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal 3Beta_HSD PF01073.19 KXH38200.1 - 1.8e-66 224.1 0.0 2.2e-66 223.7 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KXH38200.1 - 4.4e-32 111.4 0.4 7.4e-32 110.7 0.2 1.4 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXH38200.1 - 3.9e-18 66.0 0.0 1.7e-15 57.3 0.0 2.3 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KXH38200.1 - 3e-15 56.1 0.2 4.2e-15 55.6 0.2 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 KXH38200.1 - 1.9e-12 46.9 0.2 2.1e-09 36.9 0.0 2.1 1 1 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 KXH38200.1 - 5e-12 46.1 0.1 7.1e-12 45.6 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KXH38200.1 - 2.1e-07 30.4 0.1 8.3e-07 28.4 0.2 1.9 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_3 PF03447.16 KXH38200.1 - 0.0014 19.3 0.0 0.0026 18.4 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain KR PF08659.10 KXH38200.1 - 0.0015 18.5 1.7 0.01 15.7 1.7 2.2 1 1 0 1 1 1 1 KR domain adh_short PF00106.25 KXH38200.1 - 0.12 11.8 0.2 0.23 10.9 0.2 1.5 1 1 0 1 1 1 0 short chain dehydrogenase GCP_N_terminal PF17681.1 KXH38202.1 - 1.2e-28 100.6 0.0 1.8e-28 100.1 0.0 1.2 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 KXH38202.1 - 1.9e-24 86.7 0.0 3.5e-24 85.8 0.0 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal Senescence PF06911.12 KXH38203.1 - 3.3e-55 187.2 4.5 5.1e-55 186.6 4.5 1.3 1 0 0 1 1 1 1 Senescence-associated protein Zip PF02535.22 KXH38206.1 - 1.5e-56 192.1 6.6 8e-56 189.7 6.6 1.8 1 1 0 1 1 1 1 ZIP Zinc transporter Bul1_C PF04426.12 KXH38207.1 - 4.4e-05 23.0 0.0 8.1e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Bul1 C terminus Arrestin_N PF00339.29 KXH38207.1 - 0.00021 21.3 0.0 0.0015 18.6 0.0 2.3 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Bul1_N PF04425.12 KXH38207.1 - 0.0013 17.6 0.9 0.034 12.9 0.1 2.9 1 1 2 3 3 3 1 Bul1 N terminus EMP70 PF02990.16 KXH38208.1 - 3.5e-207 689.2 0.0 4.4e-207 688.9 0.0 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 adh_short_C2 PF13561.6 KXH38222.1 - 1.3e-52 178.7 0.4 2.4e-52 177.8 0.4 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXH38222.1 - 6.9e-48 162.7 0.4 8.7e-48 162.4 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXH38222.1 - 6.4e-10 39.2 0.3 9.3e-10 38.7 0.3 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXH38222.1 - 0.13 11.7 0.2 0.92 8.9 0.2 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family zf-C2H2 PF00096.26 KXH38223.1 - 1.8e-07 31.2 13.4 0.00012 22.3 1.5 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type Zn_clus PF00172.18 KXH38223.1 - 6.1e-05 23.0 11.3 6.1e-05 23.0 11.3 2.4 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-H2C2_2 PF13465.6 KXH38223.1 - 0.0017 18.7 1.7 0.0017 18.7 1.7 3.5 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KXH38223.1 - 0.039 14.8 1.2 0.039 14.8 1.2 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KXH38223.1 - 0.097 13.0 3.0 0.74 10.2 0.7 2.6 1 1 1 2 2 2 0 Zinc-finger double-stranded RNA-binding NTS_2 PF15448.6 KXH38223.1 - 0.12 12.8 0.0 0.36 11.2 0.0 1.7 1 0 0 1 1 1 0 N-terminal segments of P. falciparum erythrocyte membrane protein zf-met PF12874.7 KXH38223.1 - 0.59 10.6 3.0 28 5.3 0.2 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.6 KXH38223.1 - 1.9 8.5 5.7 0.45 10.5 0.3 2.8 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-C2H2_11 PF16622.5 KXH38223.1 - 6 6.7 7.0 31 4.4 0.1 3.1 2 0 0 2 2 2 0 zinc-finger C2H2-type ADH_zinc_N PF00107.26 KXH38224.1 - 2.1e-07 31.0 0.1 3e-06 27.3 0.0 2.4 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXH38224.1 - 0.002 18.0 0.0 0.0043 16.9 0.0 1.5 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PPR_2 PF13041.6 KXH38225.1 - 2.3e-05 24.5 0.0 4.4 7.6 0.0 4.6 4 0 0 4 4 4 2 PPR repeat family PPR PF01535.20 KXH38225.1 - 0.00042 20.4 0.0 1.3 9.4 0.0 3.9 3 0 0 3 3 3 2 PPR repeat DUF3850 PF12961.7 KXH38225.1 - 0.064 13.3 0.0 0.17 11.9 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3850) Ribosomal_S18 PF01084.20 KXH38226.1 - 1.1e-11 44.8 0.1 2e-11 43.9 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S18 S4 PF01479.25 KXH38227.1 - 3e-11 42.8 0.0 7.8e-11 41.5 0.0 1.7 2 0 0 2 2 2 1 S4 domain Ribosomal_S4 PF00163.19 KXH38227.1 - 1.2e-09 38.9 0.5 1.9e-09 38.3 0.5 1.4 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain THDPS_N_2 PF14805.6 KXH38227.1 - 0.046 14.0 0.0 0.089 13.0 0.0 1.6 1 0 0 1 1 1 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal Glyco_hydro_61 PF03443.14 KXH38228.1 - 4.5e-66 222.7 0.1 5.4e-66 222.4 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 RCR PF12273.8 KXH38229.1 - 0.012 16.3 8.5 0.14 12.8 8.5 2.2 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red CopD PF05425.13 KXH38229.1 - 0.11 12.9 0.1 0.17 12.3 0.1 1.3 1 0 0 1 1 1 0 Copper resistance protein D UPF0254 PF06787.11 KXH38229.1 - 0.26 11.1 0.0 0.34 10.7 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0254) CPSF_A PF03178.15 KXH38231.1 - 3.6e-81 273.0 0.0 9.1e-81 271.7 0.0 1.7 2 0 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.9 KXH38231.1 - 4.2e-16 58.6 0.0 1.5e-15 56.8 0.0 2.0 2 1 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term LMBR1 PF04791.16 KXH38232.1 - 2.5e-16 59.7 20.1 1.6e-13 50.4 20.1 2.3 1 1 0 1 1 1 1 LMBR1-like membrane protein TMEM208_SND2 PF05620.11 KXH38232.1 - 0.71 9.6 0.0 0.71 9.6 0.0 4.1 6 0 0 6 6 6 0 SRP-independent targeting protein 2/TMEM208 DUF5134 PF17197.4 KXH38232.1 - 3 7.7 5.9 13 5.7 2.9 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF5134) CEBP_ZZ PF16366.5 KXH38233.1 - 0.1 12.8 3.6 0.19 12.0 3.6 1.4 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain zf-B_box PF00643.24 KXH38233.1 - 0.45 10.7 3.4 0.79 9.9 3.4 1.4 1 0 0 1 1 1 0 B-box zinc finger UDG PF03167.19 KXH38235.1 - 2.2e-18 66.7 0.0 5.7e-18 65.4 0.0 1.7 1 1 0 1 1 1 1 Uracil DNA glycosylase superfamily Glyco_hydro_47 PF01532.20 KXH38236.1 - 4.3e-116 388.5 0.0 5.8e-116 388.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_transf_22 PF03901.17 KXH38244.1 - 6.3e-75 253.0 14.0 7.4e-75 252.7 14.0 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family CFEM PF05730.11 KXH38302.1 - 2.7e-14 53.0 13.4 2.7e-14 53.0 13.4 1.7 2 0 0 2 2 2 1 CFEM domain Adeno_PV PF03910.13 KXH38302.1 - 1.1 7.9 5.7 1.4 7.5 5.7 1.1 1 0 0 1 1 1 0 Adenovirus minor core protein PV Sporozoite_P67 PF05642.11 KXH38302.1 - 1.2 7.2 6.7 1.2 7.1 6.7 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Zn_clus PF00172.18 KXH38304.1 - 4e-09 36.4 8.4 8.7e-09 35.4 8.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DIOX_N PF14226.6 KXH38305.1 - 1.7e-26 93.3 0.1 2.8e-26 92.6 0.1 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KXH38305.1 - 2.1e-22 79.5 0.2 8.3e-22 77.6 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.16 KXH38307.1 - 2e-30 105.9 33.0 2e-30 105.9 33.0 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH38307.1 - 5.9e-07 28.7 14.7 5.9e-07 28.7 14.7 3.8 2 2 1 4 4 4 1 Sugar (and other) transporter Gly-zipper_YMGG PF13441.6 KXH38307.1 - 1.3 8.8 7.3 3 7.6 3.9 2.9 2 0 0 2 2 2 0 YMGG-like Gly-zipper Gly-zipper_Omp PF13488.6 KXH38307.1 - 5.8 7.0 9.9 2.6 8.1 4.8 3.0 2 1 0 2 2 2 0 Glycine zipper zf-MYND PF01753.18 KXH38310.1 - 9.9e-09 35.1 17.4 2.2e-08 34.0 17.4 1.6 1 0 0 1 1 1 1 MYND finger PolC_DP2 PF03833.13 KXH38310.1 - 0.065 11.1 4.4 0.081 10.8 4.4 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-Mss51 PF13824.6 KXH38310.1 - 4.3 7.5 8.5 10 6.3 8.6 1.5 1 1 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 ADH_zinc_N PF00107.26 KXH38312.1 - 2.6e-11 43.6 0.0 4.8e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXH38312.1 - 1.8e-06 27.8 1.0 1e-05 25.3 0.7 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KXH38312.1 - 0.017 16.2 0.0 0.034 15.2 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase zf-C2H2 PF00096.26 KXH38313.1 - 4.1e-13 49.0 11.4 3.4e-06 27.2 2.4 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KXH38313.1 - 2e-10 40.6 16.5 1.8e-07 31.3 0.2 4.0 4 0 0 4 4 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KXH38313.1 - 6.6e-09 35.9 10.4 0.00039 21.0 1.5 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KXH38313.1 - 1.8e-08 34.2 5.4 0.00031 20.7 0.3 3.9 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KXH38313.1 - 2.4e-06 27.7 0.4 0.084 13.2 0.1 3.6 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KXH38313.1 - 2.3e-05 24.6 0.8 0.013 15.9 0.2 3.4 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 KXH38313.1 - 0.0044 16.8 7.7 0.39 10.5 0.7 4.2 4 0 0 4 4 4 1 zinc-finger C2H2-type PG_binding_2 PF08823.11 KXH38313.1 - 0.08 13.3 0.2 0.22 11.9 0.2 1.6 1 0 0 1 1 1 0 Putative peptidoglycan binding domain zf-Di19 PF05605.12 KXH38313.1 - 0.091 13.1 1.4 0.17 12.2 1.4 1.4 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Zn_ribbon_recom PF13408.6 KXH38313.1 - 0.096 13.2 0.8 0.23 12.0 0.8 1.6 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain zf-C2HE PF16278.5 KXH38313.1 - 0.28 11.7 2.6 6.4 7.3 0.4 2.5 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger LIM PF00412.22 KXH38313.1 - 0.29 11.4 3.1 17 5.8 0.1 2.4 1 1 0 2 2 2 0 LIM domain C5HCH PF17982.1 KXH38313.1 - 4.2 7.6 6.2 29 4.9 1.3 2.5 1 1 1 2 2 2 0 NSD Cys-His rich domain zf-C2H2 PF00096.26 KXH38318.1 - 5.9e-06 26.4 11.6 0.0026 18.1 1.6 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KXH38318.1 - 0.00027 21.2 3.8 0.00027 21.2 3.8 2.6 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KXH38318.1 - 0.00029 21.4 11.0 0.072 14.0 2.9 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger PBP1_TM PF14812.6 KXH38318.1 - 6 7.3 6.9 14 6.1 6.9 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Tannase PF07519.11 KXH38319.1 - 2.3e-83 280.7 0.0 2.9e-83 280.4 0.0 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Hydrolase_4 PF12146.8 KXH38319.1 - 0.0036 16.6 0.0 0.022 14.0 0.0 2.1 3 0 0 3 3 3 1 Serine aminopeptidase, S33 Glyco_hydro_47 PF01532.20 KXH38320.1 - 5e-174 579.5 0.0 5.8e-174 579.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 SKG6 PF08693.10 KXH38321.1 - 0.013 14.9 0.5 0.013 14.9 0.5 2.1 3 0 0 3 3 3 0 Transmembrane alpha-helix domain EphA2_TM PF14575.6 KXH38321.1 - 0.017 16.0 0.0 0.039 14.8 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain LapA_dom PF06305.11 KXH38321.1 - 0.19 11.6 3.4 0.42 10.5 3.4 1.6 1 1 0 1 1 1 0 Lipopolysaccharide assembly protein A domain COesterase PF00135.28 KXH38322.1 - 3.3e-56 191.2 6.2 1.9e-55 188.7 6.2 2.0 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXH38322.1 - 0.0035 17.2 1.2 0.025 14.4 0.3 2.6 2 1 0 2 2 2 1 alpha/beta hydrolase fold Ank_2 PF12796.7 KXH38323.1 - 2.5e-05 24.7 0.0 4.8e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXH38323.1 - 0.00015 22.0 0.0 0.22 12.2 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 KXH38323.1 - 0.00019 21.6 0.1 0.00042 20.5 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 KXH38323.1 - 0.00089 19.6 0.0 0.61 10.6 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 KXH38323.1 - 0.016 15.8 0.0 0.037 14.6 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Glyco_hydro_75 PF07335.11 KXH38327.1 - 6.7e-68 228.1 0.3 8.8e-68 227.7 0.3 1.2 1 0 0 1 1 1 1 Fungal chitosanase of glycosyl hydrolase group 75 Sugar_tr PF00083.24 KXH38329.1 - 2.3e-100 336.6 29.6 2.9e-100 336.3 29.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH38329.1 - 1.9e-23 83.0 38.4 4e-23 81.9 30.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Trp_oprn_chp PF09534.10 KXH38329.1 - 0.011 15.6 1.8 2.8 7.7 0.1 2.6 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF2530 PF10745.9 KXH38329.1 - 4.4 7.6 14.1 1.1 9.6 2.4 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2530) Aspzincin_M35 PF14521.6 KXH38330.1 - 4.3e-36 124.6 3.8 1.3e-35 123.0 3.8 1.9 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase Peptidase_M35 PF02102.15 KXH38330.1 - 1.9e-28 99.4 16.1 2.8e-28 98.8 16.1 1.2 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family HRXXH PF13933.6 KXH38330.1 - 3.9e-05 23.3 2.2 3.9e-05 23.3 2.2 1.9 2 0 0 2 2 2 1 Putative peptidase family CARDB PF07705.11 KXH38330.1 - 0.0076 16.5 0.2 0.0076 16.5 0.2 2.6 2 1 0 2 2 2 1 CARDB Inhibitor_I67 PF11405.8 KXH38330.1 - 7.7 6.9 7.0 0.78 10.1 2.0 1.9 2 0 0 2 2 2 0 Bromelain inhibitor VI Glyco_hydro_18 PF00704.28 KXH38331.1 - 1.3e-61 209.0 3.9 1.6e-61 208.7 3.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 CCSAP PF15748.5 KXH38332.1 - 0.01 16.0 8.6 0.012 15.8 8.6 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated PPP4R2 PF09184.11 KXH38332.1 - 0.94 9.0 7.7 0.95 9.0 7.7 1.1 1 0 0 1 1 1 0 PPP4R2 DUF773 PF05600.12 KXH38333.1 - 0.39 9.4 2.4 0.62 8.7 2.4 1.2 1 0 0 1 1 1 0 CDK5 regulatory subunit-associated protein 3 M20_dimer PF07687.14 KXH38335.1 - 3.2e-25 88.2 0.0 9.1e-25 86.7 0.0 1.7 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 KXH38335.1 - 9.1e-18 64.7 0.8 2.5e-16 60.0 0.8 2.1 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.17 KXH38335.1 - 0.0017 18.1 0.0 0.0037 17.0 0.0 1.5 2 0 0 2 2 2 1 Peptidase family M28 ADH_zinc_N PF00107.26 KXH38336.1 - 6.2e-16 58.6 0.5 1.6e-15 57.2 0.3 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXH38336.1 - 2.1e-08 35.3 0.0 6.2e-08 33.8 0.0 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXH38336.1 - 0.009 15.9 0.0 0.028 14.3 0.0 1.8 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain zf-HIT PF04438.16 KXH38337.1 - 0.034 14.0 9.6 0.061 13.2 9.6 1.4 1 0 0 1 1 1 0 HIT zinc finger zf-MYND PF01753.18 KXH38337.1 - 0.17 12.0 14.3 0.35 11.0 14.3 1.6 1 1 0 1 1 1 0 MYND finger D123 PF07065.14 KXH38339.1 - 2.3e-05 23.7 0.0 2.6e-05 23.5 0.0 1.0 1 0 0 1 1 1 1 D123 DUF4413 PF14372.6 KXH38339.1 - 0.22 11.9 0.0 2 8.8 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4413) D123 PF07065.14 KXH38340.1 - 7.5e-05 22.0 0.0 8.4e-05 21.9 0.0 1.1 1 0 0 1 1 1 1 D123 R2K_3 PF14243.6 KXH38340.1 - 0.034 14.2 0.0 0.075 13.0 0.0 1.6 1 1 1 2 2 2 0 ATP-grasp domain, R2K clade family 3 WD40 PF00400.32 KXH38341.1 - 1.5e-20 73.2 31.1 0.0018 19.0 0.5 10.3 11 0 0 11 11 11 5 WD domain, G-beta repeat NACHT PF05729.12 KXH38341.1 - 6.1e-17 62.0 0.0 1.2e-16 61.0 0.0 1.5 1 0 0 1 1 1 1 NACHT domain ANAPC4_WD40 PF12894.7 KXH38341.1 - 1.7e-11 44.2 1.2 0.011 16.0 0.0 6.8 5 2 2 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KXH38341.1 - 9.7e-05 22.3 0.5 0.48 10.3 0.0 4.5 3 2 2 5 5 5 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KXH38341.1 - 0.00026 19.8 0.6 0.054 12.1 0.0 3.0 2 1 1 3 3 3 1 Nucleoporin Nup120/160 PD40 PF07676.12 KXH38341.1 - 0.0023 17.8 1.5 57 3.8 0.0 6.1 7 0 0 7 7 7 0 WD40-like Beta Propeller Repeat AAA_16 PF13191.6 KXH38341.1 - 0.0055 17.1 0.1 0.015 15.7 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain CDtoxinA PF03498.14 KXH38341.1 - 0.024 14.2 0.0 0.07 12.7 0.0 1.7 1 0 0 1 1 1 0 Cytolethal distending toxin A/C domain AAA_19 PF13245.6 KXH38341.1 - 0.15 12.4 0.0 0.34 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Ge1_WD40 PF16529.5 KXH38341.1 - 0.2 10.5 4.5 2.9 6.7 0.1 4.0 3 2 1 5 5 5 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PNP_UDP_1 PF01048.20 KXH38342.1 - 6.3e-14 51.8 0.1 1.4e-13 50.7 0.1 1.6 1 1 0 1 1 1 1 Phosphorylase superfamily Sugar_tr PF00083.24 KXH38346.1 - 1.1e-72 245.3 22.8 1.1e-72 245.3 22.8 1.7 2 0 0 2 2 2 1 Sugar (and other) transporter Peptidase_S8 PF00082.22 KXH38346.1 - 2.7e-47 161.5 0.7 4.1e-47 160.9 0.7 1.2 1 0 0 1 1 1 1 Subtilase family MFS_1 PF07690.16 KXH38346.1 - 9.1e-29 100.5 46.5 2e-17 63.2 14.7 2.3 1 1 0 2 2 2 2 Major Facilitator Superfamily fn3_5 PF06280.12 KXH38346.1 - 3.6e-05 24.4 0.0 7e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Fn3-like domain OATP PF03137.20 KXH38346.1 - 0.0043 15.4 2.5 0.0064 14.8 1.3 1.8 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family Inhibitor_I9 PF05922.16 KXH38346.1 - 0.014 16.0 0.0 0.03 15.0 0.0 1.5 1 0 0 1 1 1 0 Peptidase inhibitor I9 PA PF02225.22 KXH38346.1 - 0.086 12.9 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 PA domain Trep_Strep PF09605.10 KXH38346.1 - 0.61 10.0 12.2 1.3 8.9 1.3 2.9 1 1 1 2 2 2 0 Hypothetical bacterial integral membrane protein (Trep_Strep) PSII PF00421.19 KXH38348.1 - 0.012 14.3 0.0 0.012 14.3 0.0 1.0 1 0 0 1 1 1 0 Photosystem II protein ATG2_CAD PF13329.6 KXH38360.1 - 1.8e-55 187.0 1.8 3.6e-55 185.9 1.5 1.8 2 0 0 2 2 2 1 Autophagy-related protein 2 CAD motif ATG_C PF09333.11 KXH38360.1 - 2.1e-33 114.5 0.7 1.6e-32 111.7 0.1 2.9 4 0 0 4 4 4 1 Autophagy-related protein C terminal domain Chorein_N PF12624.7 KXH38360.1 - 1.6e-06 28.2 0.1 6.4e-06 26.3 0.1 2.0 2 0 0 2 2 2 1 N-terminal region of Chorein or VPS13 VPS13_C PF16909.5 KXH38360.1 - 0.1 12.4 0.1 0.27 11.0 0.1 1.7 1 0 0 1 1 1 0 Vacuolar-sorting-associated 13 protein C-terminal Amino_oxidase PF01593.24 KXH38361.1 - 1.1e-43 150.1 0.0 2.5e-43 149.0 0.0 1.6 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KXH38361.1 - 1.2e-14 54.3 0.1 3.3e-14 52.9 0.0 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXH38361.1 - 2.3e-06 27.1 0.0 3.7e-05 23.1 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXH38361.1 - 4.4e-05 24.0 0.1 0.00011 22.7 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXH38361.1 - 0.00013 21.2 0.3 0.00029 20.1 0.3 1.6 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 KXH38361.1 - 0.0002 21.4 0.1 0.16 11.9 0.1 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding DAO PF01266.24 KXH38361.1 - 0.00074 19.2 1.4 0.0011 18.6 0.1 2.0 3 0 0 3 3 3 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KXH38361.1 - 0.0011 17.8 0.2 0.0049 15.6 0.1 1.9 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.19 KXH38361.1 - 0.012 14.9 1.0 0.019 14.2 1.0 1.2 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 KXH38361.1 - 0.016 14.5 0.0 0.027 13.7 0.0 1.3 1 0 0 1 1 1 0 Thi4 family FAD_oxidored PF12831.7 KXH38361.1 - 0.022 14.1 0.0 0.032 13.6 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase 3HCDH_N PF02737.18 KXH38361.1 - 0.033 14.1 0.6 0.07 13.0 0.2 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 KXH38361.1 - 0.078 12.0 0.4 0.12 11.4 0.4 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.22 KXH38361.1 - 0.19 10.8 0.1 0.39 9.8 0.1 1.5 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 KXH38361.1 - 0.99 8.6 2.3 0.92 8.7 0.7 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Acyl-CoA_dh_1 PF00441.24 KXH38363.1 - 1.8e-33 115.9 0.8 2.5e-33 115.4 0.8 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.28 KXH38363.1 - 1e-18 67.2 0.0 2.4e-18 66.0 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.19 KXH38363.1 - 4.7e-18 65.2 0.1 7.9e-18 64.5 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KXH38363.1 - 2.4e-12 47.5 0.0 1.5e-11 44.9 0.0 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KXH38363.1 - 4.5e-05 23.7 0.0 8.3e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DUF3963 PF13124.6 KXH38363.1 - 4.5 7.3 4.5 1.4 9.0 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3963) zf-CCHC PF00098.23 KXH38364.1 - 9.1e-25 85.6 28.3 3.6e-09 36.3 4.0 3.8 4 0 0 4 4 4 3 Zinc knuckle zf-CCHC_4 PF14392.6 KXH38364.1 - 4.4e-07 29.5 12.3 0.0067 16.1 0.6 3.2 3 0 0 3 3 3 3 Zinc knuckle zf-CCHC_3 PF13917.6 KXH38364.1 - 1.1e-05 25.2 15.3 0.054 13.5 0.5 3.3 1 1 2 3 3 3 3 Zinc knuckle zf-CCHC_2 PF13696.6 KXH38364.1 - 1.9e-05 24.3 15.8 0.1 12.5 2.1 3.4 3 0 0 3 3 3 3 Zinc knuckle zf-CCHC_6 PF15288.6 KXH38364.1 - 0.00013 21.7 19.9 0.044 13.6 1.2 3.3 2 1 1 3 3 3 3 Zinc knuckle zf-CCHC_5 PF14787.6 KXH38364.1 - 0.0042 16.7 13.8 0.16 11.7 0.8 3.3 2 1 1 3 3 3 3 GAG-polyprotein viral zinc-finger TRAF6_Z2 PF18048.1 KXH38364.1 - 0.14 12.3 3.5 14 5.9 0.1 3.4 3 0 0 3 3 3 0 TNF receptor-associated factor 6 zinc finger 2 zinc-ribbons_6 PF07191.12 KXH38364.1 - 2.4 8.2 12.0 9.1 6.3 12.0 1.9 1 1 1 2 2 2 0 zinc-ribbons NinD PF17466.2 KXH38364.1 - 3.3 7.8 11.6 3.9 7.6 5.9 2.6 2 1 0 2 2 2 0 Family of unknown function PolC_DP2 PF03833.13 KXH38364.1 - 3.7 5.3 4.9 4.2 5.1 4.9 1.2 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Ntox16 PF15523.6 KXH38364.1 - 6.4 7.1 12.8 16 5.8 0.6 3.3 2 1 1 3 3 3 0 Novel toxin 16 IBR PF01485.21 KXH38364.1 - 6.4 7.1 14.8 1.3e+03 -0.3 14.8 2.9 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain DUF1815 PF08844.10 KXH38364.1 - 9.6 6.3 8.4 34 4.5 0.6 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF1815) SAE2 PF08573.10 KXH38365.1 - 9.3e-35 120.1 0.0 9.3e-35 120.1 0.0 3.7 3 1 0 4 4 4 1 DNA repair protein endonuclease SAE2/CtIP C-terminus KIAA1430 PF13879.6 KXH38365.1 - 0.0098 16.6 3.2 0.031 15.0 2.7 2.2 1 1 1 2 2 2 1 KIAA1430 homologue UPF0242 PF06785.11 KXH38365.1 - 0.024 14.8 8.7 0.42 10.7 3.2 2.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Trimer_CC PF08954.11 KXH38365.1 - 0.07 12.7 4.2 0.045 13.3 0.9 2.5 2 0 0 2 2 2 0 Trimerisation motif TPR_MLP1_2 PF07926.12 KXH38365.1 - 5.6 7.0 20.1 0.16 12.0 4.7 2.8 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein UCH PF00443.29 KXH38366.1 - 5.3e-47 160.5 0.0 8.8e-47 159.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KXH38366.1 - 3.6e-09 36.7 0.0 0.002 17.8 0.0 2.6 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Pkinase PF00069.25 KXH38367.1 - 3.4e-71 239.7 0.0 6.3e-71 238.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXH38367.1 - 4.8e-49 167.0 0.0 8e-49 166.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXH38367.1 - 5.7e-05 22.1 0.0 0.0001 21.3 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KXH38367.1 - 0.0038 16.6 0.0 0.027 13.8 0.1 2.0 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KXH38367.1 - 0.15 11.4 0.0 0.29 10.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Mito_fiss_reg PF05308.11 KXH38368.1 - 1.5 8.9 8.1 2.1 8.3 2.6 2.4 2 0 0 2 2 2 0 Mitochondrial fission regulator Mur_ligase_M PF08245.12 KXH38369.1 - 2.8e-05 24.2 0.8 6.1e-05 23.1 0.1 1.9 2 1 0 2 2 2 1 Mur ligase middle domain Peptidase_S9 PF00326.21 KXH38371.1 - 0.063 12.7 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family ICE2 PF08426.10 KXH38372.1 - 9.3e-159 528.9 9.9 1.1e-158 528.7 9.9 1.0 1 0 0 1 1 1 1 ICE2 FA_desaturase PF00487.24 KXH38374.1 - 4.2e-25 89.0 18.2 4.2e-25 89.0 18.2 1.7 1 1 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.10 KXH38374.1 - 1.3e-18 66.2 0.2 2.4e-18 65.3 0.2 1.5 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) Motile_Sperm PF00635.26 KXH38375.1 - 8e-25 86.8 0.5 3.4e-24 84.8 0.7 2.0 1 1 1 2 2 2 1 MSP (Major sperm protein) domain ASH PF15780.5 KXH38375.1 - 0.0025 18.0 1.0 0.0051 17.0 0.1 2.0 2 0 0 2 2 2 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin UBA PF00627.31 KXH38376.1 - 7.8e-07 28.9 0.2 2.2e-06 27.4 0.0 1.9 2 0 0 2 2 2 1 UBA/TS-N domain UBX PF00789.20 KXH38376.1 - 4.9e-06 26.7 0.0 1.4e-05 25.2 0.0 1.8 1 0 0 1 1 1 1 UBX domain THRAP3_BCLAF1 PF15440.6 KXH38376.1 - 0.01 14.9 18.7 0.012 14.7 18.7 1.1 1 0 0 1 1 1 0 THRAP3/BCLAF1 family DUF1258 PF06869.12 KXH38376.1 - 0.019 14.5 0.1 0.029 13.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1258) zf-C2H2_6 PF13912.6 KXH38376.1 - 0.03 14.3 0.3 0.058 13.4 0.3 1.4 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KXH38376.1 - 0.053 13.9 0.7 0.12 12.7 0.2 1.7 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 KXH38376.1 - 0.069 13.6 0.4 0.14 12.7 0.4 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type SOBP PF15279.6 KXH38376.1 - 2.7 8.5 4.9 3.8 8.0 4.9 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein CpXC PF14353.6 KXH38376.1 - 6.7 6.8 11.5 75 3.4 11.4 2.6 1 1 0 1 1 1 0 CpXC protein RskA PF10099.9 KXH38376.1 - 7.2 6.9 14.9 0.044 14.1 5.6 2.0 3 0 0 3 3 3 0 Anti-sigma-K factor rskA Ribosomal_60s PF00428.19 KXH38377.1 - 7.9e-27 93.7 10.5 9.5e-27 93.4 10.5 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF2408 PF10303.9 KXH38378.1 - 7.8e-39 133.3 7.2 2.1e-24 86.6 0.1 5.0 2 2 2 4 4 4 3 Protein of unknown function (DUF2408) Laminin_II PF06009.12 KXH38378.1 - 0.12 12.4 1.7 0.4 10.7 0.5 2.3 2 0 0 2 2 2 0 Laminin Domain II Csm1_N PF18504.1 KXH38378.1 - 0.44 10.9 6.3 4.2 7.8 0.3 3.7 4 0 0 4 4 4 0 Csm1 N-terminal domain MFS_1 PF07690.16 KXH38379.1 - 1.1e-30 106.8 47.8 1.3e-30 106.5 47.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH38379.1 - 1.5e-05 24.1 34.3 0.00071 18.6 18.9 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter Peptidase_M28 PF04389.17 KXH38380.1 - 6e-40 137.0 0.0 9.9e-40 136.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KXH38380.1 - 2.5e-11 43.7 0.6 2.6e-10 40.4 0.4 2.5 2 1 0 2 2 2 1 Peptidase family M20/M25/M40 Nicastrin PF05450.15 KXH38380.1 - 0.0003 20.3 0.2 0.011 15.2 0.0 2.2 2 0 0 2 2 2 1 Nicastrin Peptidase_M42 PF05343.14 KXH38380.1 - 0.056 12.5 0.0 0.2 10.6 0.0 1.9 1 1 1 2 2 2 0 M42 glutamyl aminopeptidase AAA PF00004.29 KXH38381.1 - 1.7e-06 28.5 0.0 2.5e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RTA1 PF04479.13 KXH38394.1 - 4e-61 206.2 8.4 4.5e-61 206.1 8.4 1.0 1 0 0 1 1 1 1 RTA1 like protein DUF1772 PF08592.11 KXH38394.1 - 0.0035 17.6 3.8 0.011 16.1 3.8 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF1772) DUF5592 PF17332.2 KXH38394.1 - 7 7.3 10.0 41 4.8 0.8 3.7 2 1 1 3 3 3 0 Family of unknown function (DUF5592) Fungal_trans_2 PF11951.8 KXH38395.1 - 0.00028 19.8 0.2 0.00037 19.4 0.2 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain RPN7 PF10602.9 KXH38396.1 - 7e-43 146.3 0.0 1.3e-42 145.5 0.0 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 KXH38396.1 - 1.2e-13 51.5 0.0 2.6e-13 50.4 0.0 1.6 1 0 0 1 1 1 1 PCI domain TPR_2 PF07719.17 KXH38396.1 - 0.13 12.5 0.0 4 7.8 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat PRP4 PF08799.11 KXH38397.1 - 1.8e-12 46.6 3.5 1.8e-12 46.6 3.5 3.0 3 0 0 3 3 3 1 pre-mRNA processing factor 4 (PRP4) like Prp18 PF02840.15 KXH38397.1 - 1.8e-07 31.3 0.0 1.8e-07 31.3 0.0 2.0 2 1 0 2 2 2 1 Prp18 domain CDC27 PF09507.10 KXH38397.1 - 0.33 10.3 17.9 0.65 9.3 17.9 1.4 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 V_ATPase_I PF01496.19 KXH38397.1 - 0.97 7.3 2.0 1.3 6.8 2.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CDC45 PF02724.14 KXH38397.1 - 1.2 7.4 10.0 1.2 7.4 10.0 1.2 1 0 0 1 1 1 0 CDC45-like protein MAJIN PF15077.6 KXH38397.1 - 6.7 6.4 10.0 8.8 6.0 9.4 1.6 1 1 0 1 1 1 0 Membrane-anchored junction protein SAP18 PF06487.12 KXH38398.1 - 6.9e-45 152.7 0.0 9.1e-45 152.3 0.0 1.1 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) NDUF_B4 PF07225.12 KXH38399.1 - 0.0034 17.3 0.0 0.0036 17.2 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) Tom7 PF08038.12 KXH38399.1 - 0.094 12.4 0.5 0.76 9.5 0.7 2.0 2 0 0 2 2 2 0 TOM7 family PPR_2 PF13041.6 KXH38400.1 - 3.8e-24 84.6 0.1 2.7e-10 40.3 0.0 5.9 5 1 1 6 6 6 5 PPR repeat family PPR_3 PF13812.6 KXH38400.1 - 7.7e-20 70.7 0.0 1.2e-09 38.1 0.0 4.4 4 0 0 4 4 4 3 Pentatricopeptide repeat domain PPR_long PF17177.4 KXH38400.1 - 2.2e-08 33.8 0.0 0.00086 18.7 0.0 3.5 2 1 0 3 3 3 2 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 KXH38400.1 - 2.9e-08 33.4 2.3 0.068 13.5 0.1 6.2 8 0 0 8 8 8 2 PPR repeat GST_N PF02798.20 KXH38400.1 - 2.8e-07 30.8 0.1 6e-07 29.7 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KXH38400.1 - 5.4e-07 29.9 0.0 1.3e-06 28.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain PPR_1 PF12854.7 KXH38400.1 - 9.9e-07 28.4 0.0 0.19 11.4 0.0 4.3 5 0 0 5 5 5 2 PPR repeat GST_C_2 PF13410.6 KXH38400.1 - 2.3e-05 24.3 0.0 8.7e-05 22.5 0.0 2.1 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KXH38400.1 - 3.8e-05 23.9 0.0 0.00013 22.1 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KXH38400.1 - 0.00013 22.1 0.0 0.00092 19.4 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KXH38400.1 - 0.016 15.4 0.0 0.15 12.3 0.0 2.7 3 0 0 3 3 3 0 Glutathione S-transferase, C-terminal domain Exog_C PF18026.1 KXH38400.1 - 0.029 14.4 0.0 16 5.6 0.0 3.6 3 0 0 3 3 3 0 Endo/exonuclease (EXOG) C-terminal domain MRP-S27 PF10037.9 KXH38400.1 - 0.045 12.6 0.0 2.8 6.7 0.0 2.5 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S27 Peptidase_M14 PF00246.24 KXH38401.1 - 2.7e-63 214.5 0.0 3.3e-63 214.2 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase F-box-like PF12937.7 KXH38402.1 - 1e-08 34.9 0.3 2.3e-08 33.8 0.3 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXH38402.1 - 0.0087 15.9 0.0 0.046 13.6 0.0 2.2 1 0 0 1 1 1 1 F-box domain Mis12 PF05859.12 KXH38403.1 - 3.5e-44 150.1 0.3 6.1e-44 149.4 0.3 1.4 1 0 0 1 1 1 1 Mis12 protein TCTP PF00838.17 KXH38405.1 - 3.4e-70 235.7 1.6 3.9e-70 235.5 1.6 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein TMEM52 PF14979.6 KXH38406.1 - 0.084 12.8 0.7 0.15 12.0 0.7 1.4 1 0 0 1 1 1 0 Transmembrane 52 FA_hydroxylase PF04116.13 KXH38407.1 - 1.3e-22 80.5 10.5 1.3e-22 80.5 10.5 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily YL1 PF05764.13 KXH38409.1 - 1.5e-71 241.4 29.5 1.5e-71 241.4 29.5 3.0 3 0 0 3 3 3 1 YL1 nuclear protein YL1_C PF08265.11 KXH38409.1 - 1.7e-13 50.0 0.5 3e-13 49.3 0.5 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Lipase_3 PF01764.25 KXH38410.1 - 6.5e-06 26.1 0.1 1.8e-05 24.6 0.0 1.7 2 0 0 2 2 2 1 Lipase (class 3) UPF0227 PF05728.12 KXH38410.1 - 0.0031 17.5 0.0 0.0051 16.8 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) Abhydrolase_1 PF00561.20 KXH38410.1 - 0.023 14.4 0.0 0.041 13.5 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXH38410.1 - 0.049 12.9 0.0 0.086 12.1 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 VPS9 PF02204.18 KXH38411.1 - 2.1e-25 89.0 0.0 4.3e-25 87.9 0.0 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 KXH38411.1 - 0.03 14.6 1.0 0.062 13.6 0.0 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF5601) Sigma70_ner PF04546.13 KXH38411.1 - 0.21 11.4 3.2 0.24 11.3 1.7 1.8 1 1 1 2 2 2 0 Sigma-70, non-essential region CH PF00307.31 KXH38412.1 - 1.5e-46 157.0 0.1 4.2e-22 78.4 0.0 2.8 3 0 0 3 3 3 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.10 KXH38412.1 - 2.4e-23 82.0 0.3 1e-22 80.0 0.0 2.3 2 0 0 2 2 2 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.8 KXH38412.1 - 3.8e-11 42.7 0.1 7.5e-06 25.7 0.0 2.7 2 0 0 2 2 2 2 CAMSAP CH domain EF-hand_6 PF13405.6 KXH38412.1 - 0.00051 19.8 0.9 0.0029 17.4 0.1 2.7 3 0 0 3 3 3 1 EF-hand domain EF-hand_7 PF13499.6 KXH38412.1 - 0.0055 17.1 5.1 0.02 15.3 3.0 2.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 KXH38412.1 - 0.029 14.2 0.9 0.36 10.7 0.1 2.8 1 1 2 3 3 3 0 EF-hand domain pair EF-hand_1 PF00036.32 KXH38412.1 - 0.067 12.8 0.2 0.72 9.5 0.0 2.5 2 0 0 2 2 2 0 EF hand PSII_Pbs27 PF13326.6 KXH38412.1 - 0.12 12.7 1.4 0.3 11.4 1.4 1.6 1 0 0 1 1 1 0 Photosystem II Pbs27 Spectrin PF00435.21 KXH38412.1 - 0.35 11.4 4.4 5.3 7.6 2.1 2.7 2 0 0 2 2 2 0 Spectrin repeat Cytochrom_B562 PF07361.11 KXH38412.1 - 0.71 10.6 3.8 1.3 9.7 0.3 2.7 2 1 0 2 2 2 0 Cytochrome b562 TFIIF_alpha PF05793.12 KXH38412.1 - 4.1 5.9 12.2 6.9 5.1 12.2 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) FAD-oxidase_C PF02913.19 KXH38413.1 - 2.5e-59 200.9 0.0 3.7e-59 200.4 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KXH38413.1 - 3.7e-40 136.9 0.6 7.3e-40 135.9 0.6 1.5 1 0 0 1 1 1 1 FAD binding domain Zn_clus PF00172.18 KXH38414.1 - 1e-07 31.9 11.4 2.3e-07 30.8 11.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KXH38414.1 - 0.013 14.3 0.0 0.017 13.9 0.0 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain PSI_integrin PF17205.3 KXH38414.1 - 0.027 14.2 1.6 0.027 14.2 1.6 2.2 2 0 0 2 2 2 0 Integrin plexin domain Proteasome PF00227.26 KXH38415.1 - 3.6e-55 186.4 0.1 5.4e-55 185.8 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KXH38415.1 - 1.2e-11 44.0 0.4 3.7e-11 42.5 0.1 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature zf-CHY PF05495.12 KXH38416.1 - 8.1e-13 48.7 17.7 1.6e-12 47.7 17.7 1.5 1 1 0 1 1 1 1 CHY zinc finger Zn-ribbon_8 PF09723.10 KXH38416.1 - 0.032 14.4 11.5 0.49 10.6 7.2 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zinc_ribbon_9 PF14369.6 KXH38416.1 - 0.91 9.8 9.9 0.41 10.9 6.2 2.4 1 1 1 2 2 2 0 zinc-ribbon RNA_POL_M_15KD PF02150.16 KXH38416.1 - 2.1 8.3 13.0 9.3 6.2 0.0 3.3 3 0 0 3 3 3 0 RNA polymerases M/15 Kd subunit HypA PF01155.19 KXH38416.1 - 3.9 7.5 13.2 4.5 7.3 10.1 2.1 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA ERCC3_RAD25_C PF16203.5 KXH38417.1 - 1.7e-122 407.4 0.2 3e-122 406.6 0.2 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 KXH38417.1 - 1.3e-33 115.8 0.0 1e-32 112.9 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXH38417.1 - 6.9e-16 58.7 0.0 1.5e-15 57.6 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KXH38417.1 - 4.5e-11 43.1 0.1 1.2e-10 41.7 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 KXH38417.1 - 4.1e-07 29.0 0.0 5.3e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain SBP_bac_6 PF13343.6 KXH38417.1 - 0.15 11.5 0.0 0.37 10.2 0.0 1.6 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein TrkH PF02386.16 KXH38418.1 - 5.7e-143 477.0 7.0 1.1e-142 476.1 2.8 2.0 2 0 0 2 2 2 2 Cation transport protein Ribosomal_L19 PF01245.20 KXH38419.1 - 4e-11 42.8 0.0 6e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L19 SM-ATX PF14438.6 KXH38419.1 - 0.23 11.6 0.0 0.41 10.8 0.0 1.4 1 0 0 1 1 1 0 Ataxin 2 SM domain FANCF PF11107.8 KXH38420.1 - 0.015 14.5 0.2 0.028 13.7 0.2 1.4 1 0 0 1 1 1 0 Fanconi anemia group F protein (FANCF) PALP PF00291.25 KXH38421.1 - 7.7e-67 225.8 0.4 9e-67 225.5 0.4 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme zf-C3HC4 PF00097.25 KXH38422.1 - 5e-07 29.5 4.9 5e-07 29.5 4.9 5.1 5 2 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) SH3_9 PF14604.6 KXH38422.1 - 8.4e-07 28.8 0.1 1.6e-06 27.8 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain zf-RING_UBOX PF13445.6 KXH38422.1 - 3.9e-06 26.8 4.5 3.9e-06 26.8 4.5 4.0 5 0 0 5 5 5 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KXH38422.1 - 1e-05 25.3 3.2 1e-05 25.3 3.2 5.6 6 1 1 7 7 7 1 Zinc finger, C3HC4 type (RING finger) SH3_1 PF00018.28 KXH38422.1 - 1.6e-05 24.4 0.1 3.6e-05 23.3 0.1 1.6 1 0 0 1 1 1 1 SH3 domain zf-RING_6 PF14835.6 KXH38422.1 - 2.6e-05 24.0 0.6 2.6e-05 24.0 0.6 3.6 3 0 0 3 3 3 1 zf-RING of BARD1-type protein zf-RING_2 PF13639.6 KXH38422.1 - 5.1e-05 23.5 4.9 5.1e-05 23.5 4.9 5.1 4 2 1 5 5 5 1 Ring finger domain zf-RING_5 PF14634.6 KXH38422.1 - 0.00027 20.8 3.8 0.00027 20.8 3.8 5.4 6 1 1 7 7 7 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KXH38422.1 - 0.013 15.7 7.3 0.013 15.7 7.3 4.4 5 0 0 5 5 5 0 zinc finger of C3HC4-type, RING SH3_2 PF07653.17 KXH38422.1 - 0.031 13.9 0.1 0.11 12.2 0.0 1.9 2 0 0 2 2 2 0 Variant SH3 domain ECH_1 PF00378.20 KXH38423.1 - 9.5e-77 257.7 0.0 1.1e-76 257.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXH38423.1 - 1.3e-37 130.0 0.1 1.3e-34 120.2 0.1 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Thg1 PF04446.12 KXH38423.1 - 0.037 14.1 0.0 0.075 13.1 0.0 1.5 1 0 0 1 1 1 0 tRNAHis guanylyltransferase Rer1 PF03248.13 KXH38424.1 - 4.3e-76 254.4 9.3 5e-76 254.2 9.3 1.0 1 0 0 1 1 1 1 Rer1 family Paf1 PF03985.13 KXH38425.1 - 5.3e-85 286.0 0.0 5.9e-85 285.8 0.0 1.0 1 0 0 1 1 1 1 Paf1 Glyco_transf_90 PF05686.12 KXH38426.1 - 5.7e-17 61.7 7.4 9.8e-15 54.3 5.4 2.5 2 1 0 2 2 2 2 Glycosyl transferase family 90 IspD PF01128.19 KXH38426.1 - 0.11 12.3 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Nucleoside_tran PF01733.18 KXH38428.1 - 1.7e-37 129.5 4.9 1.7e-37 129.5 4.9 1.9 2 0 0 2 2 2 1 Nucleoside transporter MFS_1 PF07690.16 KXH38428.1 - 0.002 17.1 8.1 0.002 17.1 8.1 2.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Ins_P5_2-kin PF06090.12 KXH38429.1 - 3e-48 165.0 0.1 4e-48 164.6 0.1 1.2 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase YEATS PF03366.16 KXH38432.1 - 1.3e-29 101.9 0.2 2.1e-29 101.3 0.2 1.3 1 0 0 1 1 1 1 YEATS family DarA_C PF18789.1 KXH38432.1 - 0.014 15.6 0.1 0.047 14.0 0.0 1.9 2 0 0 2 2 2 0 Defence against restriction A C-terminal SYF2 PF08231.12 KXH38434.1 - 1.3e-55 188.2 15.3 1.3e-55 188.2 15.3 1.7 2 0 0 2 2 2 1 SYF2 splicing factor Adenylsucc_synt PF00709.21 KXH38434.1 - 0.18 10.7 1.8 0.37 9.7 0.2 2.0 1 1 1 2 2 2 0 Adenylosuccinate synthetase Kelch_5 PF13854.6 KXH38436.1 - 7.7e-13 48.1 13.2 7.7e-09 35.4 0.5 5.5 5 0 0 5 5 5 3 Kelch motif Kelch_4 PF13418.6 KXH38436.1 - 2.8e-10 40.0 12.7 0.00021 21.2 0.3 5.5 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_6 PF13964.6 KXH38436.1 - 3.5e-06 27.1 18.1 0.62 10.4 0.1 5.3 4 1 1 5 5 5 4 Kelch motif Kelch_1 PF01344.25 KXH38436.1 - 2e-05 24.1 0.5 0.72 9.5 0.0 4.0 3 1 0 3 3 3 2 Kelch motif Podoplanin PF05808.11 KXH38436.1 - 0.12 12.5 0.1 0.22 11.6 0.1 1.4 1 0 0 1 1 1 0 Podoplanin VSP PF03302.13 KXH38436.1 - 0.16 10.8 0.7 0.24 10.2 0.7 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein SKG6 PF08693.10 KXH38436.1 - 0.17 11.3 1.0 0.31 10.5 1.0 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Kelch_2 PF07646.15 KXH38436.1 - 0.46 10.6 13.4 1 9.5 0.0 5.7 7 0 0 7 7 7 0 Kelch motif Glyco_hydro_16 PF00722.21 KXH38437.1 - 1.5e-11 44.1 1.2 2.2e-11 43.6 1.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Ecl1 PF12855.7 KXH38438.1 - 7.6e-40 137.9 20.5 7.6e-40 137.9 20.5 1.8 2 0 0 2 2 2 1 ECL1/2/3 zinc binding proteins zf-FLZ PF04570.14 KXH38438.1 - 0.0015 18.0 3.0 0.0031 16.9 3.0 1.5 1 0 0 1 1 1 1 zinc-finger of the FCS-type, C2-C2 PLATZ PF04640.14 KXH38438.1 - 0.024 15.3 1.9 0.042 14.5 1.9 1.4 1 0 0 1 1 1 0 PLATZ transcription factor zf-MYND PF01753.18 KXH38438.1 - 0.15 12.2 2.4 0.27 11.4 2.4 1.4 1 0 0 1 1 1 0 MYND finger DUF2256 PF10013.9 KXH38438.1 - 2.7 8.2 7.2 35 4.6 7.2 2.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2256) DUF3176 PF11374.8 KXH38439.1 - 2.1e-30 105.1 1.3 2.1e-30 105.1 1.3 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) MgtE PF01769.16 KXH38439.1 - 0.86 10.0 8.5 0.4 11.1 0.7 2.8 3 0 0 3 3 3 0 Divalent cation transporter Haspin_kinase PF12330.8 KXH38440.1 - 1.7e-35 122.6 0.0 2.5e-35 122.1 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain DUF4863 PF16155.5 KXH38440.1 - 0.085 12.7 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4863) DUF1682 PF07946.14 KXH38441.1 - 5.7e-115 383.9 1.8 6.6e-115 383.7 1.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) Big_3 PF07523.12 KXH38441.1 - 0.15 12.4 0.1 9.7 6.6 0.1 2.4 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 3) DUF2140 PF09911.9 KXH38441.1 - 0.31 10.6 0.0 0.31 10.6 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2140) DUF4407 PF14362.6 KXH38441.1 - 1.8 7.9 8.1 2.7 7.3 8.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Transp_cyt_pur PF02133.15 KXH38442.1 - 2.2e-25 89.3 33.4 5e-25 88.2 33.4 1.6 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin MFS_1 PF07690.16 KXH38444.1 - 1.8e-36 125.8 24.6 1.8e-36 125.8 24.6 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 KXH38444.1 - 4.6e-06 26.2 2.3 4.6e-06 26.2 2.3 2.1 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB DUF2206 PF09971.9 KXH38444.1 - 0.00069 18.5 0.1 0.00069 18.5 0.1 1.8 2 0 0 2 2 2 1 Predicted membrane protein (DUF2206) HET PF06985.11 KXH38445.1 - 1.6e-26 93.4 0.1 2.9e-26 92.6 0.1 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Helo_like_N PF17111.5 KXH38446.1 - 0.0013 18.1 7.3 0.0029 17.0 5.2 2.5 1 1 1 2 2 2 1 Fungal N-terminal domain of STAND proteins LRR_6 PF13516.6 KXH38446.1 - 0.05 13.7 1.8 0.059 13.5 0.3 2.0 2 0 0 2 2 2 0 Leucine Rich repeat LMBR1 PF04791.16 KXH38446.1 - 0.094 11.6 2.5 0.13 11.1 2.5 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DASH_Dad2 PF08654.10 KXH38446.1 - 4 7.9 6.6 2.2 8.8 0.2 2.8 2 1 0 2 2 2 0 DASH complex subunit Dad2 Kelch_5 PF13854.6 KXH38449.1 - 1.2e-11 44.3 4.8 9.4e-11 41.5 0.4 3.9 4 0 0 4 4 4 1 Kelch motif stn_TNFRSF12A PF12191.8 KXH38449.1 - 0.0089 16.2 0.4 0.021 15.0 0.4 1.6 1 0 0 1 1 1 1 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Kelch_1 PF01344.25 KXH38449.1 - 0.25 10.9 4.5 2.7 7.6 0.3 3.6 3 1 0 3 3 3 0 Kelch motif PTP_tm PF18861.1 KXH38449.1 - 0.56 10.2 1.9 1.8 8.5 1.7 1.9 2 0 0 2 2 2 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J DUF2603 PF10788.9 KXH38451.1 - 0.085 12.9 0.3 0.38 10.8 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2603) Nbl1_Borealin_N PF10444.9 KXH38451.1 - 0.17 11.5 3.0 0.54 9.9 0.7 2.8 2 0 0 2 2 2 0 Nbl1 / Borealin N terminal Virul_fac_BrkB PF03631.15 KXH38451.1 - 0.24 11.0 0.0 0.44 10.1 0.0 1.3 1 0 0 1 1 1 0 Virulence factor BrkB Helo_like_N PF17111.5 KXH38451.1 - 0.43 9.9 7.3 0.27 10.6 4.2 2.3 2 1 0 2 2 2 0 Fungal N-terminal domain of STAND proteins HrpB7 PF09486.10 KXH38451.1 - 0.89 9.9 7.2 0.5 10.8 1.8 2.5 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) Ras PF00071.22 KXH38453.1 - 1.9e-59 199.9 0.2 2.3e-59 199.6 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXH38453.1 - 2.3e-20 73.0 0.0 3.4e-20 72.5 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXH38453.1 - 2.2e-08 33.8 0.0 2.5e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KXH38453.1 - 9.3e-06 25.3 0.1 5.2e-05 22.9 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KXH38453.1 - 0.00018 21.5 0.3 0.77 9.6 0.0 2.4 1 1 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KXH38453.1 - 0.0021 18.1 0.0 0.0034 17.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 KXH38453.1 - 0.006 16.6 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain FeoB_N PF02421.18 KXH38453.1 - 0.0066 16.0 0.0 0.012 15.1 0.0 1.5 1 1 0 1 1 1 1 Ferrous iron transport protein B ATP_bind_1 PF03029.17 KXH38453.1 - 0.22 11.3 1.5 2.7 7.7 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein MoCF_biosynth PF00994.24 KXH38454.1 - 3.6e-35 120.7 0.0 5.5e-35 120.1 0.0 1.3 1 0 0 1 1 1 1 Probable molybdopterin binding domain Cofilin_ADF PF00241.20 KXH38455.1 - 2.5e-19 69.3 0.1 3e-19 69.0 0.1 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein ParA PF10609.9 KXH38456.1 - 1.6e-92 309.4 0.0 1.9e-92 309.2 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 KXH38456.1 - 1e-08 35.3 0.0 2e-08 34.4 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 KXH38456.1 - 0.00032 20.7 0.1 0.0037 17.2 0.1 2.1 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.15 KXH38456.1 - 0.00045 19.5 0.1 0.0033 16.6 0.1 2.1 2 0 0 2 2 2 1 Anion-transporting ATPase Fer4_NifH PF00142.18 KXH38456.1 - 0.002 17.6 0.0 1.1 8.6 0.0 2.2 2 0 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_25 PF13481.6 KXH38456.1 - 0.0038 16.8 0.1 0.0064 16.1 0.1 1.3 1 0 0 1 1 1 1 AAA domain MipZ PF09140.11 KXH38456.1 - 0.0097 15.2 0.0 0.021 14.1 0.0 1.5 1 1 0 1 1 1 1 ATPase MipZ AAA_26 PF13500.6 KXH38456.1 - 0.014 15.2 0.0 2.4 8.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KXH38456.1 - 0.021 14.5 0.0 0.033 13.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KXH38456.1 - 0.023 14.6 0.0 0.046 13.6 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 KXH38456.1 - 0.057 13.8 0.0 0.11 12.9 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain CLP1_P PF16575.5 KXH38456.1 - 0.076 12.8 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop RNA_helicase PF00910.22 KXH38456.1 - 0.098 13.1 0.0 0.19 12.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase TsaE PF02367.17 KXH38456.1 - 0.1 12.6 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zn_Tnp_IS1595 PF12760.7 KXH38456.1 - 0.11 12.5 0.0 0.32 11.0 0.0 1.7 1 0 0 1 1 1 0 Transposase zinc-ribbon domain VirE PF05272.11 KXH38456.1 - 0.14 11.9 0.0 0.47 10.2 0.0 1.8 2 0 0 2 2 2 0 Virulence-associated protein E HEAT_2 PF13646.6 KXH38457.1 - 2.8e-26 91.7 9.2 1e-12 48.3 0.2 4.1 2 2 2 4 4 4 2 HEAT repeats HEAT_PBS PF03130.16 KXH38457.1 - 3.2e-19 67.6 4.7 0.0034 17.9 0.0 6.8 6 0 0 6 6 6 5 PBS lyase HEAT-like repeat HEAT PF02985.22 KXH38457.1 - 2.4e-08 33.5 3.5 0.77 10.2 0.0 5.9 6 1 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.6 KXH38457.1 - 9.3e-07 29.2 7.9 0.62 10.6 0.0 6.0 3 2 2 5 5 5 4 HEAT-like repeat TFIIS_C PF01096.18 KXH38458.1 - 1.8e-15 56.5 1.6 1.8e-15 56.5 1.6 3.3 3 1 1 4 4 4 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 KXH38458.1 - 0.00032 20.5 3.9 0.00032 20.5 3.9 2.6 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit zf-ribbon_3 PF13248.6 KXH38458.1 - 0.013 14.9 7.0 0.89 9.1 0.1 3.5 3 0 0 3 3 3 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 KXH38458.1 - 0.014 15.5 6.5 0.52 10.5 0.1 2.7 2 0 0 2 2 2 0 Zinc ribbon domain UCH_1 PF13423.6 KXH38458.1 - 0.035 13.7 2.4 0.04 13.5 2.4 1.1 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Lar_restr_allev PF14354.6 KXH38458.1 - 0.072 13.5 11.3 0.44 11.0 0.6 3.1 2 1 0 2 2 2 0 Restriction alleviation protein Lar zinc_ribbon_2 PF13240.6 KXH38458.1 - 0.085 12.6 15.7 0.8 9.5 0.3 3.8 4 0 0 4 4 4 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.7 KXH38458.1 - 0.41 10.6 6.0 0.78 9.8 0.3 2.5 2 1 0 2 2 2 0 Transposase zinc-ribbon domain zf-ISL3 PF14690.6 KXH38458.1 - 0.73 10.6 5.1 8.9 7.1 0.1 3.0 3 0 0 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Nudix_N_2 PF14803.6 KXH38458.1 - 0.84 9.6 9.3 4.4 7.3 0.1 2.8 2 1 0 2 2 2 0 Nudix N-terminal zf-IS66 PF13005.7 KXH38458.1 - 1 9.9 15.0 3.3 8.2 0.1 3.5 3 1 1 4 4 3 0 zinc-finger binding domain of transposase IS66 OrfB_Zn_ribbon PF07282.11 KXH38458.1 - 1 9.3 11.4 0.85 9.6 1.3 2.8 2 2 1 3 3 3 0 Putative transposase DNA-binding domain DUF1922 PF09082.10 KXH38458.1 - 1.8 8.9 5.3 0.91 9.9 0.2 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF1922) NOB1_Zn_bind PF08772.11 KXH38458.1 - 1.9 8.7 11.2 17 5.7 5.0 3.0 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like zf_UBZ PF18439.1 KXH38458.1 - 3.4 7.4 8.9 13 5.5 0.0 3.4 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf-trcl PF13451.6 KXH38458.1 - 4.4 7.3 9.8 5.1 7.1 0.1 3.3 3 0 0 3 3 3 0 Probable zinc-ribbon domain Nipped-B_C PF12830.7 KXH38459.1 - 3.3e-51 174.0 1.6 3.3e-51 174.0 1.6 2.6 3 0 0 3 3 3 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.7 KXH38459.1 - 1.9e-07 31.3 1.1 9e-07 29.1 0.3 2.5 2 0 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion Adaptin_N PF01602.20 KXH38459.1 - 5.3e-07 28.6 0.1 9e-06 24.5 0.0 2.7 3 0 0 3 3 3 1 Adaptin N terminal region HEAT PF02985.22 KXH38459.1 - 8.3e-05 22.5 0.8 0.55 10.6 0.0 4.3 4 0 0 4 4 4 2 HEAT repeat Cnd1 PF12717.7 KXH38459.1 - 0.0018 18.3 0.1 0.042 13.9 0.0 2.5 1 1 1 2 2 2 1 non-SMC mitotic condensation complex subunit 1 NT5C PF06941.12 KXH38459.1 - 0.08 12.8 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) FNIP_N PF14636.6 KXH38460.1 - 3.9e-40 138.3 0.3 3.9e-40 138.3 0.3 4.3 4 2 0 4 4 4 1 Folliculin-interacting protein N-terminus FNIP_M PF14637.6 KXH38460.1 - 0.047 13.7 0.1 0.27 11.2 0.0 2.0 1 1 1 2 2 2 0 Folliculin-interacting protein middle domain PH_6 PF15406.6 KXH38578.1 - 0.026 14.8 0.3 0.04 14.2 0.2 1.4 1 1 0 1 1 1 0 Pleckstrin homology domain RRM_1 PF00076.22 KXH38578.1 - 0.17 11.7 0.0 0.29 11.0 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) adh_short PF00106.25 KXH38579.1 - 2.7e-18 66.1 0.0 1.8e-12 47.1 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXH38579.1 - 2.6e-08 33.7 0.0 0.00049 19.7 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH38579.1 - 0.0012 18.8 0.0 0.0018 18.2 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF4813 PF16072.5 KXH38579.1 - 2.9 7.5 8.1 0.26 10.9 1.6 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4813) Tannase PF07519.11 KXH38581.1 - 1.5e-79 268.1 0.2 1.7e-79 267.9 0.2 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_S9 PF00326.21 KXH38581.1 - 9.9e-08 31.7 0.0 0.0011 18.5 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KXH38581.1 - 0.0063 16.2 2.3 0.007 16.0 0.1 2.1 2 1 1 3 3 3 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXH38581.1 - 0.0072 15.6 0.0 0.023 13.9 0.0 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 PHO4 PF01384.20 KXH38582.1 - 8.7e-102 340.6 17.0 1e-101 340.4 17.0 1.0 1 0 0 1 1 1 1 Phosphate transporter family UPF0444 PF15475.6 KXH38582.1 - 4 7.8 10.0 1.2 9.4 0.7 2.8 2 0 0 2 2 2 0 Transmembrane protein C12orf23, UPF0444 Tmemb_40 PF10160.9 KXH38582.1 - 5.6 6.3 7.7 2.3 7.6 3.9 2.0 1 1 0 2 2 2 0 Predicted membrane protein MFS_1 PF07690.16 KXH38583.1 - 1.3e-18 67.1 26.4 1.3e-18 67.1 26.4 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH38583.1 - 5.5e-06 25.5 8.1 5.5e-06 25.5 8.1 2.7 1 1 2 3 3 3 1 Sugar (and other) transporter S_4TM PF18159.1 KXH38583.1 - 1 8.6 3.9 0.27 10.5 0.3 1.9 2 0 0 2 2 2 0 SMODS-associating 4TM effector domain DUF4149 PF13664.6 KXH38583.1 - 7.2 7.0 8.9 0.35 11.2 0.3 3.2 2 1 0 3 3 3 0 Domain of unknown function (DUF4149) DUF3723 PF12520.8 KXH38585.1 - 3e-75 253.9 3.2 5.9e-73 246.3 3.2 2.8 1 1 0 1 1 1 1 Protein of unknown function (DUF3723) Herpes_UL73 PF03554.13 KXH38585.1 - 0.09 12.8 0.4 0.24 11.4 0.4 1.7 1 0 0 1 1 1 0 UL73 viral envelope glycoprotein Zn_clus PF00172.18 KXH38587.1 - 1.9e-08 34.3 8.2 4e-08 33.3 8.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain F-box-like PF12937.7 KXH38588.1 - 0.002 17.9 0.1 0.0057 16.5 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXH38588.1 - 0.039 13.8 0.2 0.13 12.2 0.0 1.9 2 0 0 2 2 2 0 F-box domain TES PF08034.11 KXH38589.1 - 0.09 13.1 1.0 0.16 12.3 1.0 1.3 1 0 0 1 1 1 0 Trematode eggshell synthesis protein IgaA PF07095.11 KXH38589.1 - 0.24 9.4 0.0 0.28 9.1 0.0 1.0 1 0 0 1 1 1 0 Intracellular growth attenuator protein IgaA PALP PF00291.25 KXH38591.1 - 1.1e-42 146.5 0.3 1.3e-42 146.2 0.3 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme LYTB PF02401.18 KXH38591.1 - 0.1 11.9 0.0 0.19 10.9 0.0 1.4 1 0 0 1 1 1 0 LytB protein TauD PF02668.16 KXH38592.1 - 1e-32 114.0 0.1 1.5e-32 113.5 0.1 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 KXH38592.1 - 0.065 12.3 0.0 0.1 11.7 0.0 1.4 1 1 0 1 1 1 0 CsiD DUF917 PF06032.12 KXH38593.1 - 1.7e-120 402.1 1.4 2.9e-120 401.3 1.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF917) Hydant_A_N PF05378.13 KXH38593.1 - 8e-33 113.6 0.1 4e-30 104.8 0.0 2.8 3 0 0 3 3 3 2 Hydantoinase/oxoprolinase N-terminal region Hydantoinase_A PF01968.18 KXH38593.1 - 3.4e-28 98.7 10.4 2e-27 96.2 0.6 3.3 2 1 1 3 3 3 2 Hydantoinase/oxoprolinase MutL PF13941.6 KXH38593.1 - 0.0023 16.6 3.8 0.0037 15.9 0.0 2.5 3 0 0 3 3 3 1 MutL protein BcrAD_BadFG PF01869.20 KXH38593.1 - 0.0028 17.2 1.5 0.097 12.1 0.0 3.1 3 1 0 3 3 3 1 BadF/BadG/BcrA/BcrD ATPase family StbA PF06406.11 KXH38593.1 - 0.016 14.5 0.0 4.4 6.4 0.0 2.5 2 0 0 2 2 2 0 StbA protein FtsA PF14450.6 KXH38593.1 - 0.019 15.4 1.7 4 7.9 0.1 2.8 2 0 0 2 2 2 0 Cell division protein FtsA Transp_cyt_pur PF02133.15 KXH38594.1 - 6.6e-91 305.3 37.4 7.9e-91 305.0 37.4 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Prenyltrans PF00432.21 KXH38594.1 - 0.082 12.7 0.1 1.6 8.5 0.0 3.0 2 0 0 2 2 2 0 Prenyltransferase and squalene oxidase repeat HNH_2 PF13391.6 KXH38595.1 - 3.7e-09 36.6 0.0 9.7e-09 35.2 0.0 1.7 1 0 0 1 1 1 1 HNH endonuclease p25-alpha PF05517.12 KXH38595.1 - 0.068 13.3 0.6 0.12 12.5 0.6 1.3 1 0 0 1 1 1 0 p25-alpha TFIIF_alpha PF05793.12 KXH38595.1 - 1 7.9 7.7 1.7 7.1 7.7 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Fungal_trans PF04082.18 KXH38596.1 - 7.8e-10 38.2 0.0 9.4e-07 28.1 0.0 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain Amidohydro_2 PF04909.14 KXH38597.1 - 2.2e-28 99.9 0.5 3.8e-28 99.1 0.5 1.4 1 1 0 1 1 1 1 Amidohydrolase FAD_binding_4 PF01565.23 KXH38600.1 - 6.5e-23 81.0 2.5 6.7e-23 81.0 1.2 1.7 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 KXH38600.1 - 0.0018 18.3 0.1 0.0036 17.4 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like Peptidase_M43 PF05572.13 KXH38601.1 - 5e-14 52.5 0.6 1.3e-13 51.2 0.2 2.0 1 1 1 2 2 2 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 KXH38601.1 - 6.4e-05 23.2 0.9 0.0001 22.5 0.9 1.4 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 KXH38601.1 - 0.00094 18.9 0.0 0.0017 18.0 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 KXH38601.1 - 0.0061 16.5 0.2 0.011 15.7 0.1 1.7 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 KXH38601.1 - 0.0072 16.2 0.0 0.0086 15.9 0.0 1.3 1 0 0 1 1 1 1 Matrixin Reprolysin_3 PF13582.6 KXH38601.1 - 0.047 14.2 1.8 0.12 12.9 1.8 2.0 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M7 PF02031.16 KXH38601.1 - 0.09 12.9 0.4 0.45 10.6 0.0 2.2 2 0 0 2 2 2 0 Streptomyces extracellular neutral proteinase (M7) family Peptidase_M66 PF10462.9 KXH38601.1 - 0.13 11.2 3.4 0.14 11.1 2.1 1.5 1 1 0 1 1 1 0 Peptidase M66 DUF4953 PF16313.5 KXH38601.1 - 0.26 10.4 0.7 0.47 9.6 0.7 1.3 1 0 0 1 1 1 0 Met-zincin FAD_binding_3 PF01494.19 KXH38602.1 - 1.2e-22 80.7 0.0 8.2e-22 77.9 0.0 2.1 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 KXH38602.1 - 0.0052 15.9 0.7 1.9 7.4 0.1 2.7 3 0 0 3 3 3 2 Lycopene cyclase protein Amino_oxidase PF01593.24 KXH38602.1 - 0.0084 15.4 0.5 0.13 11.5 0.1 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Trp_halogenase PF04820.14 KXH38602.1 - 0.036 12.9 1.1 0.71 8.6 0.3 2.6 2 1 0 3 3 3 0 Tryptophan halogenase NAD_binding_8 PF13450.6 KXH38602.1 - 0.085 13.1 0.3 0.085 13.1 0.3 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXH38602.1 - 0.12 11.6 1.0 2.6 7.2 1.0 2.2 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXH38602.1 - 0.18 11.1 4.4 0.45 9.7 0.6 2.6 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Glyco_hydro_43 PF04616.14 KXH38603.1 - 5.6e-32 111.2 0.4 7.4e-32 110.8 0.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GspH PF12019.8 KXH38603.1 - 1.7 9.1 4.9 1.5 9.3 0.1 3.0 3 1 1 4 4 4 0 Type II transport protein GspH AbrB_C PF18277.1 KXH38604.1 - 0.053 13.2 0.1 0.099 12.3 0.1 1.4 1 0 0 1 1 1 0 AbrB C-terminal domain Arf PF00025.21 KXH38616.1 - 1.5e-65 219.9 0.0 1.7e-65 219.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 KXH38616.1 - 2.3e-10 40.2 0.0 4.8e-07 29.3 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 KXH38616.1 - 2.3e-07 30.4 0.0 3.2e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 KXH38616.1 - 3.9e-07 29.8 0.0 5.3e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXH38616.1 - 4.7e-07 30.0 0.0 1.3e-06 28.6 0.0 1.7 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KXH38616.1 - 9.5e-07 28.9 0.0 1.3e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KXH38616.1 - 4e-05 23.1 0.0 4.9e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KXH38616.1 - 0.008 15.7 0.0 0.19 11.2 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain DUF2457 PF10446.9 KXH38617.1 - 3.1e-125 419.0 23.6 3.4e-125 418.8 17.7 3.9 2 2 2 4 4 4 2 Protein of unknown function (DUF2457) ATP-synt_DE_N PF02823.16 KXH38618.1 - 7.3e-18 64.2 0.0 1.2e-17 63.6 0.0 1.3 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain FYVE PF01363.21 KXH38619.1 - 0.0027 17.8 3.7 0.0061 16.7 3.7 1.6 1 0 0 1 1 1 1 FYVE zinc finger Siva PF05458.12 KXH38619.1 - 0.003 17.3 2.3 0.0071 16.1 2.3 1.6 1 0 0 1 1 1 1 Cd27 binding protein (Siva) NOB1_Zn_bind PF08772.11 KXH38619.1 - 0.0033 17.5 1.4 0.0075 16.4 1.4 1.6 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like Zn_Tnp_IS91 PF14319.6 KXH38619.1 - 0.0056 16.7 1.2 0.015 15.3 1.2 1.7 1 0 0 1 1 1 1 Transposase zinc-binding domain zinc_ribbon_2 PF13240.6 KXH38619.1 - 0.016 14.9 7.3 0.17 11.7 2.8 2.8 1 1 1 2 2 2 0 zinc-ribbon domain zf-C3HC4_3 PF13920.6 KXH38619.1 - 0.032 14.1 4.6 0.058 13.3 4.6 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXH38619.1 - 0.048 13.5 4.6 0.097 12.6 4.6 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DZR PF12773.7 KXH38619.1 - 0.12 12.5 8.0 0.88 9.7 8.1 2.2 1 1 0 1 1 1 0 Double zinc ribbon TerY_C PF15616.6 KXH38619.1 - 1.2 9.2 4.6 7.3 6.7 0.2 2.4 2 0 0 2 2 2 0 TerY-C metal binding domain zf-ribbon_3 PF13248.6 KXH38619.1 - 3.8 7.0 10.8 11 5.6 0.6 2.8 1 1 1 2 2 2 0 zinc-ribbon domain zf-B_box PF00643.24 KXH38619.1 - 6.4 7.0 13.9 0.043 14.0 4.3 2.2 2 0 0 2 2 2 0 B-box zinc finger UPF0547 PF10571.9 KXH38619.1 - 6.4 7.0 12.7 1.5 9.0 1.2 2.6 2 1 0 2 2 2 0 Uncharacterised protein family UPF0547 Peptidase_M2 PF01401.18 KXH38620.1 - 0.23 10.0 5.2 0.1 11.2 2.6 1.6 2 0 0 2 2 2 0 Angiotensin-converting enzyme Cylicin_N PF15241.6 KXH38620.1 - 3 8.0 9.5 0.76 9.9 1.2 2.4 2 0 0 2 2 2 0 Cylicin N-terminus DnaJ PF00226.31 KXH38621.1 - 6.4e-16 58.2 1.2 2.3e-15 56.5 1.2 2.0 1 0 0 1 1 1 1 DnaJ domain Sec63 PF02889.16 KXH38621.1 - 2.6e-11 43.2 0.0 6.1e-10 38.7 0.0 2.5 2 1 0 2 2 2 1 Sec63 Brl domain MCR_D PF02505.14 KXH38621.1 - 0.057 13.3 0.3 0.16 11.8 0.1 1.8 2 0 0 2 2 2 0 Methyl-coenzyme M reductase operon protein D DUF4045 PF13254.6 KXH38622.1 - 5.5e-93 312.9 49.8 4.4e-58 197.9 36.5 8.2 4 3 4 8 8 8 2 Domain of unknown function (DUF4045) Gelsolin PF00626.22 KXH38622.1 - 2.5e-07 30.5 0.0 0.021 14.7 0.0 3.3 3 0 0 3 3 3 2 Gelsolin repeat Arf PF00025.21 KXH38623.1 - 1.8e-67 226.1 0.7 2.1e-67 226.0 0.7 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 KXH38623.1 - 1.3e-12 47.5 0.8 3.4e-07 29.8 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 KXH38623.1 - 2.1e-12 47.3 0.1 2.9e-12 46.9 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KXH38623.1 - 2.7e-12 46.6 0.0 3.1e-12 46.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KXH38623.1 - 2.8e-10 39.9 0.0 3.4e-10 39.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KXH38623.1 - 2.6e-08 34.0 0.0 4.1e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 KXH38623.1 - 3.3e-08 33.2 0.0 3.9e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 KXH38623.1 - 0.00011 21.8 0.0 0.0021 17.7 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain NACHT PF05729.12 KXH38623.1 - 0.023 14.6 0.3 0.25 11.3 0.0 2.0 2 0 0 2 2 2 0 NACHT domain FeoB_N PF02421.18 KXH38623.1 - 0.028 14.0 0.2 0.078 12.5 0.2 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B Dynamin_N PF00350.23 KXH38623.1 - 0.064 13.3 0.0 0.75 9.8 0.0 2.0 2 0 0 2 2 2 0 Dynamin family 6PF2K PF01591.18 KXH38623.1 - 0.13 11.5 0.0 0.31 10.3 0.0 1.6 2 0 0 2 2 2 0 6-phosphofructo-2-kinase Acetyltransf_7 PF13508.7 KXH38624.1 - 0.00035 20.9 0.0 0.001 19.4 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXH38624.1 - 0.016 15.5 0.0 0.042 14.1 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_13 PF13880.6 KXH38624.1 - 0.1 12.6 0.0 0.3 11.1 0.0 1.7 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase DUF2791 PF10923.8 KXH38625.1 - 0.069 12.0 0.0 0.096 11.5 0.0 1.1 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) GST_C PF00043.25 KXH38630.1 - 1.6e-08 34.6 0.0 2.7e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KXH38630.1 - 2.6e-06 27.3 0.0 1.5e-05 24.9 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KXH38630.1 - 3.2e-06 27.3 0.0 5.3e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KXH38630.1 - 0.00028 21.2 0.0 0.00055 20.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KXH38630.1 - 0.0039 17.5 0.0 0.0085 16.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KXH38630.1 - 0.008 16.5 0.0 0.021 15.1 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 KXH38630.1 - 0.044 13.6 0.0 0.096 12.5 0.0 1.6 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain MFS_1 PF07690.16 KXH38631.1 - 1.2e-33 116.6 21.8 1.2e-33 116.6 21.8 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily DHDPS PF00701.22 KXH38632.1 - 2.6e-38 131.4 0.0 3e-38 131.2 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family p450 PF00067.22 KXH38633.1 - 3e-61 207.6 0.0 7.2e-61 206.3 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Pyr_redox_2 PF07992.14 KXH38634.1 - 2.5e-34 118.9 0.0 3.1e-34 118.5 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXH38634.1 - 2.3e-16 60.1 1.0 3.3e-12 46.8 0.1 3.4 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXH38634.1 - 1.2e-07 31.3 0.1 5.6e-06 25.8 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXH38634.1 - 0.00037 20.5 0.2 0.3 11.0 0.0 3.6 3 1 1 4 4 4 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KXH38634.1 - 0.0028 16.8 0.7 0.004 16.3 0.0 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.17 KXH38634.1 - 0.026 13.8 0.4 1.1 8.4 0.0 2.4 2 0 0 2 2 2 0 Thi4 family TrkA_N PF02254.18 KXH38634.1 - 0.026 14.8 1.3 12 6.2 0.0 3.5 3 1 0 3 3 3 0 TrkA-N domain DAO PF01266.24 KXH38634.1 - 0.043 13.4 5.2 0.22 11.1 0.0 3.5 4 0 0 4 4 4 0 FAD dependent oxidoreductase Malic_M PF03949.15 KXH38634.1 - 0.059 12.6 1.4 0.35 10.1 0.0 2.5 2 1 1 3 3 3 0 Malic enzyme, NAD binding domain Trp_halogenase PF04820.14 KXH38634.1 - 0.097 11.5 2.2 12 4.6 0.7 2.9 2 1 0 3 3 3 0 Tryptophan halogenase ThiF PF00899.21 KXH38634.1 - 7.9 5.8 6.5 7.6 5.8 0.1 2.8 3 0 0 3 3 3 0 ThiF family MFS_1 PF07690.16 KXH38636.1 - 6.8e-41 140.4 15.8 6.8e-41 140.4 15.8 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH38636.1 - 8.3e-13 48.0 0.9 8.3e-13 48.0 0.9 2.0 2 0 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 KXH38636.1 - 0.045 12.1 3.8 0.018 13.4 0.8 1.8 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF4969 PF16339.5 KXH38636.1 - 0.16 12.3 0.2 0.35 11.2 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4969) Gly_kinase PF02595.15 KXH38637.1 - 3.6e-120 401.3 3.4 4.1e-120 401.1 3.4 1.0 1 0 0 1 1 1 1 Glycerate kinase family 5_nucleotid_C PF02872.18 KXH38638.1 - 5.7e-44 150.1 0.0 1e-43 149.3 0.0 1.4 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 KXH38638.1 - 8e-07 29.8 0.2 1.2e-06 29.2 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase YmdB PF13277.6 KXH38638.1 - 0.14 11.4 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 YmdB-like protein Methyltransf_23 PF13489.6 KXH38640.1 - 1.9e-23 83.1 0.0 2.9e-23 82.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH38640.1 - 1.2e-10 41.9 0.0 3e-10 40.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH38640.1 - 2.2e-09 37.9 0.0 1.3e-08 35.5 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH38640.1 - 6.6e-09 35.7 0.0 3e-08 33.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH38640.1 - 1.8e-06 28.5 0.0 3.8e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KXH38640.1 - 0.023 14.1 0.0 0.023 14.1 0.0 2.4 2 0 0 2 2 2 0 Putative methyltransferase MTS PF05175.14 KXH38640.1 - 0.024 14.2 0.0 0.041 13.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain FtsJ PF01728.19 KXH38640.1 - 0.035 14.2 0.0 0.063 13.4 0.0 1.5 2 0 0 2 2 2 0 FtsJ-like methyltransferase Methyltransf_2 PF00891.18 KXH38640.1 - 0.14 11.5 0.0 0.51 9.6 0.0 1.9 2 0 0 2 2 2 0 O-methyltransferase domain Methyltransf_23 PF13489.6 KXH38641.1 - 4.9e-24 85.0 0.0 1.1e-23 83.9 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH38641.1 - 4.2e-11 42.9 0.0 8.1e-10 38.7 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH38641.1 - 1.3e-09 38.6 0.0 3.5e-09 37.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH38641.1 - 1.6e-08 35.2 0.0 2.3e-07 31.5 0.0 2.6 3 1 0 3 3 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH38641.1 - 2.2e-06 28.2 0.0 4.6e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KXH38641.1 - 0.00052 19.5 0.2 0.0018 17.8 0.0 1.9 3 0 0 3 3 3 1 Putative methyltransferase Ubie_methyltran PF01209.18 KXH38641.1 - 0.01 15.2 0.0 0.74 9.1 0.0 2.5 3 0 0 3 3 3 0 ubiE/COQ5 methyltransferase family FtsJ PF01728.19 KXH38641.1 - 0.015 15.4 0.0 0.027 14.6 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase MTS PF05175.14 KXH38641.1 - 0.017 14.7 0.0 0.032 13.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.13 KXH38641.1 - 0.018 14.5 0.0 0.029 13.8 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.20 KXH38641.1 - 0.045 13.1 0.0 0.097 12.0 0.0 1.4 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_16 PF10294.9 KXH38641.1 - 0.15 11.7 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_23 PF13489.6 KXH38642.1 - 2.9e-25 89.0 0.0 5e-25 88.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH38642.1 - 4.8e-12 46.4 0.0 8.8e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH38642.1 - 8.7e-10 38.6 0.0 2.4e-09 37.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH38642.1 - 4.6e-09 36.9 0.0 9.7e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH38642.1 - 2.3e-08 34.5 0.0 4.4e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KXH38642.1 - 0.002 17.5 0.0 0.0033 16.8 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 KXH38642.1 - 0.02 14.5 0.0 0.056 13.0 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_4 PF02390.17 KXH38642.1 - 0.028 13.9 0.0 0.093 12.2 0.0 1.7 2 0 0 2 2 2 0 Putative methyltransferase PCMT PF01135.19 KXH38642.1 - 0.072 12.8 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.18 KXH38642.1 - 0.073 12.4 0.0 1.8 7.8 0.0 2.2 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family NAD_binding_10 PF13460.6 KXH38643.1 - 7.8e-35 120.4 1.3 9.7e-35 120.1 1.3 1.1 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KXH38643.1 - 5.6e-05 22.7 0.0 0.00013 21.6 0.0 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KXH38643.1 - 0.1 11.7 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain NmrA PF05368.13 KXH38643.1 - 0.1 12.1 0.1 1.4 8.4 0.0 2.2 2 0 0 2 2 2 0 NmrA-like family peroxidase PF00141.23 KXH38644.1 - 6.7e-21 75.0 0.4 1.1e-20 74.3 0.4 1.3 1 0 0 1 1 1 1 Peroxidase PSI_PSAK PF01241.18 KXH38644.1 - 0.0053 16.7 0.1 0.012 15.6 0.1 1.6 1 0 0 1 1 1 1 Photosystem I psaG / psaK FMO-like PF00743.19 KXH38645.1 - 5.6e-19 67.9 0.2 1.2e-17 63.6 0.0 2.3 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KXH38645.1 - 1.7e-14 53.8 0.4 1.2e-13 51.0 0.4 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXH38645.1 - 8.6e-11 41.6 0.0 2.3e-10 40.2 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXH38645.1 - 1.1e-09 38.4 0.0 8.6e-09 35.5 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KXH38645.1 - 6.2e-09 35.4 0.1 1.3e-07 31.1 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KXH38645.1 - 8.9e-07 28.8 1.9 0.029 13.9 0.1 3.4 1 1 1 3 3 3 2 FAD dependent oxidoreductase Thi4 PF01946.17 KXH38645.1 - 1.9e-06 27.3 0.4 2.9e-05 23.4 0.0 2.6 3 0 0 3 3 3 1 Thi4 family NAD_binding_9 PF13454.6 KXH38645.1 - 1.6e-05 24.9 3.1 0.0016 18.4 0.2 4.1 4 1 0 4 4 4 1 FAD-NAD(P)-binding HI0933_like PF03486.14 KXH38645.1 - 0.022 13.5 0.2 2.5 6.7 0.2 2.9 3 0 0 3 3 3 0 HI0933-like protein Pyr_redox PF00070.27 KXH38645.1 - 0.031 14.8 0.1 4.6 7.9 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Mqo PF06039.15 KXH38645.1 - 0.17 10.4 0.2 0.35 9.4 0.0 1.5 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) Bac_luciferase PF00296.20 KXH38646.1 - 2.3e-51 175.1 1.5 3.5e-51 174.5 1.5 1.2 1 0 0 1 1 1 1 Luciferase-like monooxygenase MFS_1 PF07690.16 KXH38647.1 - 6.3e-37 127.3 23.5 9.7e-37 126.7 23.5 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Glyoxalase PF00903.25 KXH38648.1 - 5.1e-09 36.4 0.0 8.4e-09 35.7 0.0 1.4 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KXH38648.1 - 0.0048 17.1 0.0 0.0061 16.8 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily MAGUK_N_PEST PF10608.9 KXH38649.1 - 0.0049 17.3 0.0 0.006 17.0 0.0 1.4 1 1 0 1 1 1 1 Polyubiquitination (PEST) N-terminal domain of MAGUK TraK PF06586.11 KXH38649.1 - 0.041 13.6 2.6 0.056 13.1 2.6 1.2 1 0 0 1 1 1 0 TraK protein AA_permease PF00324.21 KXH38650.1 - 1.9e-126 422.5 44.4 2.2e-126 422.3 44.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KXH38650.1 - 9.4e-28 97.2 49.3 1.3e-27 96.7 49.3 1.1 1 0 0 1 1 1 1 Amino acid permease SAD_SRA PF02182.17 KXH38652.1 - 2e-35 121.8 0.0 2.6e-35 121.4 0.0 1.2 1 0 0 1 1 1 1 SAD/SRA domain Zn_clus PF00172.18 KXH38653.1 - 3.2e-07 30.4 10.2 3.2e-07 30.4 10.2 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NmrA PF05368.13 KXH38654.1 - 6.9e-37 127.2 0.0 8.8e-37 126.9 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXH38654.1 - 2.2e-24 86.4 0.0 3.2e-24 85.8 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KXH38654.1 - 6.4e-06 25.8 0.1 2.9e-05 23.7 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.25 KXH38654.1 - 0.0058 16.1 0.2 0.0095 15.4 0.2 1.4 1 0 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.17 KXH38654.1 - 0.0064 15.6 0.1 0.57 9.2 0.0 2.1 2 0 0 2 2 2 2 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 KXH38654.1 - 0.046 13.1 0.0 0.066 12.6 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KXH38654.1 - 0.053 12.5 0.0 0.11 11.5 0.0 1.5 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family GFA PF04828.14 KXH38655.1 - 6.4e-12 45.6 15.1 1.4e-06 28.6 0.9 2.9 3 0 0 3 3 3 2 Glutathione-dependent formaldehyde-activating enzyme MFS_1 PF07690.16 KXH38656.1 - 8.1e-54 182.9 22.0 8.1e-54 182.9 22.0 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH38656.1 - 3.2e-11 42.8 5.3 3.2e-11 42.8 5.3 2.8 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 KXH38656.1 - 1.2e-07 30.5 5.3 2.6e-07 29.4 5.3 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_5 PF05631.14 KXH38656.1 - 0.0005 19.1 5.1 0.0016 17.4 2.3 2.1 2 0 0 2 2 2 1 Sugar-tranasporters, 12 TM MFS_3 PF05977.13 KXH38656.1 - 0.00092 17.7 3.9 0.00092 17.7 3.9 1.9 2 0 0 2 2 2 1 Transmembrane secretion effector Phage_holin_2_4 PF16082.5 KXH38656.1 - 0.0064 16.2 0.8 0.4 10.4 0.0 2.8 2 0 0 2 2 2 1 Bacteriophage holin family, superfamily II-like OATP PF03137.20 KXH38656.1 - 3.6 5.8 9.2 2.9 6.1 3.6 2.7 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family V-SNARE_C PF12352.8 KXH38657.1 - 2.9e-14 53.1 0.3 2.9e-14 53.1 0.3 2.6 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 KXH38657.1 - 9.5e-05 22.2 0.1 0.0015 18.4 0.0 2.6 2 1 1 3 3 3 1 Sec20 KxDL PF10241.9 KXH38657.1 - 0.0051 17.1 1.2 3.7 7.9 0.2 3.1 3 0 0 3 3 3 1 Uncharacterized conserved protein RmuC PF02646.16 KXH38657.1 - 0.0085 15.3 0.9 0.013 14.7 0.2 1.7 2 1 0 2 2 2 1 RmuC family Sigma70_r4 PF04545.16 KXH38657.1 - 0.014 14.9 0.1 0.037 13.5 0.1 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 Cytochrom_C PF00034.21 KXH38657.1 - 0.021 16.0 0.0 0.07 14.3 0.0 1.9 1 0 0 1 1 1 0 Cytochrome c Spc7 PF08317.11 KXH38657.1 - 0.077 11.9 5.2 0.11 11.4 4.6 1.4 2 0 0 2 2 2 0 Spc7 kinetochore protein BLOC1_2 PF10046.9 KXH38657.1 - 0.091 13.1 1.5 4.3 7.7 0.2 2.6 2 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CK2S PF15011.6 KXH38657.1 - 0.11 12.4 1.6 0.33 10.8 1.6 1.8 1 1 0 1 1 1 0 Casein Kinase 2 substrate F_actin_bind PF08919.10 KXH38657.1 - 0.3 11.2 2.2 0.88 9.7 2.2 1.8 1 1 0 1 1 1 0 F-actin binding RTX_C PF08339.10 KXH38657.1 - 0.31 11.1 2.2 0.58 10.2 0.9 2.0 1 1 1 2 2 2 0 RTX C-terminal domain DUF4337 PF14235.6 KXH38657.1 - 1.6 8.8 3.7 31 4.6 3.7 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4337) DUF745 PF05335.13 KXH38657.1 - 2.1 8.0 7.2 8.3 6.1 4.4 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF745) TPR_MLP1_2 PF07926.12 KXH38657.1 - 2.7 8.1 10.2 2.2 8.4 3.4 2.9 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein TPK_catalytic PF04263.16 KXH38658.1 - 1.1e-26 93.2 0.0 1.6e-26 92.7 0.0 1.1 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 KXH38658.1 - 1.2e-23 82.6 0.7 1.9e-23 81.9 0.7 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain CHCH PF06747.13 KXH38659.1 - 6.9e-06 26.1 5.0 1.1e-05 25.4 5.0 1.4 1 0 0 1 1 1 1 CHCH domain GCK PF07802.11 KXH38659.1 - 3 8.3 7.6 0.31 11.5 2.6 1.9 2 0 0 2 2 2 0 GCK domain DUF5353 PF17304.2 KXH38660.1 - 5.8e-15 54.8 4.1 9.4e-15 54.1 4.1 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5353) Transport_MerF PF11431.8 KXH38660.1 - 0.1 12.5 0.9 0.1 12.5 0.9 2.1 2 0 0 2 2 2 0 Membrane transport protein MerF Myb_DNA-bind_3 PF12776.7 KXH38661.1 - 5.6e-26 91.4 0.3 9.7e-26 90.6 0.3 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain UPF0029 PF01205.19 KXH38663.1 - 1.4e-25 89.6 0.0 3.1e-25 88.5 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 Methyltransf_23 PF13489.6 KXH38663.1 - 3.6e-18 66.0 0.0 6.7e-18 65.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH38663.1 - 0.00031 21.4 0.0 0.0011 19.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH38663.1 - 0.00048 19.9 0.0 0.066 13.0 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH38663.1 - 0.0034 18.1 0.0 2.3 9.0 0.0 3.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH38663.1 - 0.0038 17.8 0.0 0.066 13.9 0.0 2.7 1 1 0 1 1 1 1 Methyltransferase domain Exo_endo_phos PF03372.23 KXH38666.1 - 2.9e-10 40.1 0.0 5.1e-10 39.3 0.0 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Pkinase PF00069.25 KXH38667.1 - 1.2e-29 103.4 0.1 6.8e-24 84.6 0.0 2.8 2 1 1 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXH38667.1 - 8.1e-12 45.0 0.0 5.5e-11 42.2 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase DUF3905 PF13045.6 KXH38667.1 - 0.012 15.6 0.8 0.064 13.3 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3905) APH PF01636.23 KXH38667.1 - 0.04 13.8 0.2 0.074 13.0 0.2 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family NPL PF17800.1 KXH38669.1 - 9e-36 122.6 0.2 9e-36 122.6 0.2 2.1 2 2 0 2 2 2 1 Nucleoplasmin-like domain FKBP_C PF00254.28 KXH38669.1 - 7.8e-31 106.3 0.1 6.2e-30 103.4 0.0 2.3 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase DMAP1 PF05499.12 KXH38669.1 - 5.4 6.9 21.0 1.5 8.7 9.1 2.2 2 0 0 2 2 2 0 DNA methyltransferase 1-associated protein 1 (DMAP1) Glyco_trans_2_3 PF13632.6 KXH38671.1 - 5.1e-19 69.0 0.5 1.1e-18 67.9 0.5 1.5 1 0 0 1 1 1 1 Glycosyl transferase family group 2 FmiP_Thoc5 PF09766.9 KXH38672.1 - 9e-32 110.8 7.5 1.2e-31 110.3 7.5 1.1 1 0 0 1 1 1 1 Fms-interacting protein/Thoc5 DUF1640 PF07798.11 KXH38672.1 - 0.013 15.5 1.8 0.013 15.5 1.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) SPATA1_C PF15743.5 KXH38672.1 - 0.021 14.9 3.7 0.36 10.9 1.0 2.3 2 0 0 2 2 2 0 Spermatogenesis-associated C-terminus DUF3958 PF13125.6 KXH38672.1 - 0.18 12.0 6.1 4.2 7.6 2.9 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3958) Cnn_1N PF07989.11 KXH38672.1 - 0.19 11.9 5.1 0.52 10.5 0.4 2.6 2 1 0 2 2 2 0 Centrosomin N-terminal motif 1 DUF1664 PF07889.12 KXH38672.1 - 0.22 11.6 1.4 8.7 6.4 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF4200 PF13863.6 KXH38672.1 - 0.87 10.0 12.5 0.71 10.3 0.8 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) HlyIII PF03006.20 KXH38673.1 - 6.1e-59 199.5 17.5 7.4e-59 199.2 17.5 1.1 1 0 0 1 1 1 1 Haemolysin-III related Ycf66_N PF07444.11 KXH38673.1 - 0.39 10.9 3.4 0.4 10.9 0.9 2.3 2 0 0 2 2 2 0 Ycf66 protein N-terminus GP67 PF17634.2 KXH38674.1 - 0.052 14.0 8.8 0.091 13.2 8.8 1.4 1 0 0 1 1 1 0 Gene product 67 Astro_capsid_p PF12226.8 KXH38674.1 - 0.12 11.5 5.9 0.14 11.2 5.9 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein DUF4746 PF15928.5 KXH38674.1 - 0.16 11.3 4.9 0.18 11.2 4.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) CDC45 PF02724.14 KXH38674.1 - 0.6 8.3 10.9 0.63 8.3 10.9 1.1 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 KXH38674.1 - 0.63 9.3 10.1 0.81 8.9 10.1 1.2 1 0 0 1 1 1 0 NOA36 protein PBP1_TM PF14812.6 KXH38674.1 - 0.79 10.1 7.1 1.9 8.9 7.1 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nop14 PF04147.12 KXH38674.1 - 1.5 6.9 13.7 1.8 6.7 13.7 1.0 1 0 0 1 1 1 0 Nop14-like family Pes-10 PF07149.11 KXH38674.1 - 5.6 5.9 6.6 7.4 5.5 6.6 1.2 1 0 0 1 1 1 0 Pes-10 FAM176 PF14851.6 KXH38674.1 - 6.9 6.3 10.8 13 5.5 10.0 1.9 2 1 0 2 2 2 0 FAM176 family 7tm_2 PF00002.24 KXH38677.1 - 1.6e-06 27.6 12.8 1.6e-06 27.6 12.8 1.9 1 1 1 2 2 2 1 7 transmembrane receptor (Secretin family) Vma12 PF11712.8 KXH38677.1 - 1.2 9.2 3.9 6.1 6.9 0.4 3.1 3 0 0 3 3 3 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Saf_2TM PF18303.1 KXH38677.1 - 1.7 8.3 4.8 4.6 6.8 0.1 3.2 3 0 0 3 3 3 0 SAVED-fused 2TM effector domain Cellulase PF00150.18 KXH38678.1 - 2.8e-36 125.4 0.2 3.3e-36 125.2 0.2 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CRT10 PF08728.10 KXH38679.1 - 8.4e-16 57.3 0.0 8.2e-13 47.4 0.0 2.2 2 0 0 2 2 2 2 CRT10 VIR_N PF15912.5 KXH38679.1 - 4.7 6.7 7.5 8.6 5.9 7.5 1.4 1 0 0 1 1 1 0 Virilizer, N-terminal Ammonium_transp PF00909.21 KXH38680.1 - 2.9e-117 391.8 30.9 3.3e-117 391.6 30.9 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family DUF3185 PF11381.8 KXH38680.1 - 6.5 6.8 9.8 8.8 6.4 0.1 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3185) Abhydrolase_3 PF07859.13 KXH38681.1 - 8.5e-21 74.8 2.6 8.5e-21 74.8 1.2 1.8 2 1 0 2 2 2 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KXH38681.1 - 7.4e-15 54.7 0.0 9.2e-15 54.4 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase adh_short PF00106.25 KXH38682.1 - 3.9e-34 117.8 0.0 6.6e-34 117.1 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXH38682.1 - 2.3e-19 69.9 0.0 3.6e-19 69.3 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH38682.1 - 3.5e-07 30.3 0.0 8.3e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KXH38682.1 - 3.9e-06 26.5 0.1 7.7e-06 25.5 0.1 1.4 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) FMO-like PF00743.19 KXH38682.1 - 7e-06 24.7 0.0 1.1e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KXH38682.1 - 0.0019 18.4 0.0 0.0087 16.3 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KXH38682.1 - 0.0041 16.3 0.0 0.15 11.2 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) 3Beta_HSD PF01073.19 KXH38682.1 - 0.0054 15.8 0.0 0.013 14.6 0.0 1.6 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Pyr_redox_3 PF13738.6 KXH38682.1 - 0.0084 15.4 0.0 0.31 10.2 0.0 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Epimerase PF01370.21 KXH38682.1 - 0.022 14.2 0.0 0.038 13.4 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Fungal_trans PF04082.18 KXH38683.1 - 8.8e-18 64.3 0.0 2.2e-17 63.0 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain P5-ATPase PF12409.8 KXH38683.1 - 0.11 12.6 0.2 0.21 11.7 0.2 1.4 1 0 0 1 1 1 0 P5-type ATPase cation transporter p450 PF00067.22 KXH38684.1 - 1.3e-49 169.2 0.0 1.8e-49 168.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.18 KXH38686.1 - 5.4e-09 35.5 0.0 1e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH38686.1 - 2.9e-08 33.7 9.1 4.8e-08 33.0 9.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SelP_N PF04592.14 KXH38686.1 - 4.3 6.7 7.1 7.4 5.9 7.1 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Prenyltrans PF00432.21 KXH38689.1 - 2.5e-32 110.3 20.4 1.5e-07 31.0 0.2 6.2 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 KXH38689.1 - 0.06 12.4 0.0 0.22 10.6 0.0 1.9 2 0 0 2 2 2 0 Squalene-hopene cyclase C-terminal domain Zn_clus PF00172.18 KXH38690.1 - 0.0038 17.3 7.7 0.0081 16.3 7.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BRAP2 PF07576.12 KXH38691.1 - 2.4e-29 101.5 0.0 4.1e-29 100.7 0.0 1.4 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.19 KXH38691.1 - 2.1e-18 66.4 6.0 5e-18 65.2 5.3 2.0 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.6 KXH38691.1 - 6.2e-09 36.0 9.7 6.2e-09 36.0 9.7 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 KXH38691.1 - 5.5e-07 29.3 10.4 1.3e-06 28.1 10.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KXH38691.1 - 1.3e-06 28.0 4.8 5.1e-06 26.1 4.8 2.1 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 KXH38691.1 - 8.8e-06 25.5 8.6 2.5e-05 24.0 8.6 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXH38691.1 - 2.2e-05 24.4 3.9 2.2e-05 24.4 3.9 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 KXH38691.1 - 9.4e-05 22.3 8.8 9.4e-05 22.3 8.8 1.9 2 0 0 2 2 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KXH38691.1 - 0.00014 21.6 7.1 0.00014 21.6 7.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KXH38691.1 - 0.00032 20.9 7.2 0.001 19.3 7.2 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 KXH38691.1 - 0.002 17.9 11.4 0.002 17.9 11.4 2.9 2 1 1 3 3 2 1 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 KXH38691.1 - 0.0041 16.9 3.0 0.011 15.6 3.0 1.7 1 0 0 1 1 1 1 zf-RING of BARD1-type protein NBD94 PF16830.5 KXH38691.1 - 0.023 15.0 1.2 1.1 9.7 0.4 2.5 2 0 0 2 2 2 0 Nucleotide-Binding Domain 94 of RH SHE3 PF17078.5 KXH38691.1 - 0.04 13.6 11.9 0.062 13.0 11.9 1.2 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 zf-ANAPC11 PF12861.7 KXH38691.1 - 0.06 13.4 7.4 0.16 12.1 7.4 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 KXH38691.1 - 0.21 11.4 7.0 0.48 10.3 7.0 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FAM76 PF16046.5 KXH38691.1 - 0.36 10.1 7.3 0.61 9.4 7.3 1.3 1 0 0 1 1 1 0 FAM76 protein GIT_CC PF16559.5 KXH38691.1 - 0.41 10.5 4.4 4.6 7.2 0.1 2.4 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor YabA PF06156.13 KXH38691.1 - 5.4 7.7 13.0 1.7 9.3 2.1 2.4 1 1 1 2 2 2 0 Initiation control protein YabA ESCRT-II PF05871.12 KXH38692.1 - 6.3e-59 198.2 0.0 9.4e-59 197.7 0.0 1.3 1 0 0 1 1 1 1 ESCRT-II complex subunit RTT107_BRCT_5 PF16770.5 KXH38693.1 - 5.1e-34 116.1 0.0 5.1e-31 106.5 0.0 3.8 5 0 0 5 5 5 1 Regulator of Ty1 transposition protein 107 BRCT domain PTCB-BRCT PF12738.7 KXH38693.1 - 6.5e-33 112.5 0.4 1.2e-21 76.4 0.3 4.5 4 0 0 4 4 4 3 twin BRCT domain BRCT PF00533.26 KXH38693.1 - 1.1e-29 102.6 0.0 3.8e-11 43.2 0.0 5.2 6 0 0 6 6 6 4 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KXH38693.1 - 4e-27 94.4 0.0 1.5e-05 25.3 0.0 5.9 6 0 0 6 6 6 5 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 KXH38693.1 - 2.1e-08 34.3 0.0 0.054 13.8 0.0 3.6 3 0 0 3 3 3 3 DNA ligase 3 BRCT domain GMC_oxred_N PF00732.19 KXH38694.1 - 4.8e-56 190.3 0.0 6e-56 190.0 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXH38694.1 - 1.5e-32 113.1 0.0 4.1e-32 111.7 0.0 1.7 2 0 0 2 2 2 1 GMC oxidoreductase Thi4 PF01946.17 KXH38694.1 - 7.8e-05 22.0 1.0 0.0016 17.8 0.3 2.2 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 KXH38694.1 - 0.0001 21.6 0.7 0.007 15.5 0.3 2.2 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 KXH38694.1 - 0.00013 22.1 0.2 0.0004 20.6 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXH38694.1 - 0.0003 20.5 2.1 0.004 16.8 0.4 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXH38694.1 - 0.00042 19.7 0.6 0.033 13.4 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KXH38694.1 - 0.00059 19.0 0.2 0.0009 18.4 0.2 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.14 KXH38694.1 - 0.0076 15.0 0.5 0.47 9.1 0.1 2.1 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_3 PF13738.6 KXH38694.1 - 0.022 14.0 1.4 0.18 11.1 0.6 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXH38694.1 - 0.12 11.5 0.1 0.64 9.1 0.0 1.9 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) p450 PF00067.22 KXH38695.1 - 2.4e-42 145.3 0.0 9.2e-42 143.3 0.0 1.9 2 1 0 2 2 2 1 Cytochrome P450 adh_short PF00106.25 KXH38696.1 - 2.4e-26 92.4 1.4 2.9e-26 92.1 1.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXH38696.1 - 1e-22 80.9 1.5 2.4e-22 79.7 1.5 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH38696.1 - 3.6e-07 30.3 0.2 4.8e-07 29.9 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXH38696.1 - 0.00029 20.4 0.2 0.0014 18.1 0.2 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KXH38696.1 - 0.0011 18.2 0.1 0.0013 17.9 0.1 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.20 KXH38696.1 - 0.03 14.4 0.0 0.052 13.6 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase UbiA PF01040.18 KXH38698.1 - 1e-18 67.6 12.7 1.8e-18 66.8 12.4 1.5 1 1 0 1 1 1 1 UbiA prenyltransferase family FAD_binding_4 PF01565.23 KXH38699.1 - 1e-24 86.9 3.8 2e-24 85.9 3.8 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KXH38699.1 - 1.6e-07 31.3 0.1 3.2e-07 30.3 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like adh_short PF00106.25 KXH38700.1 - 0.0032 17.0 0.0 0.54 9.7 0.0 2.6 3 0 0 3 3 3 2 short chain dehydrogenase MFS_1 PF07690.16 KXH38701.1 - 2.4e-21 76.1 37.2 2.7e-21 75.9 36.8 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF3487 PF11990.8 KXH38701.1 - 2.6 7.9 5.2 14 5.6 0.7 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3487) UCR_hinge PF02320.16 KXH38702.1 - 1.2e-26 92.6 11.4 1.2e-26 92.6 11.4 2.0 2 1 0 2 2 1 1 Ubiquinol-cytochrome C reductase hinge protein Mpp10 PF04006.12 KXH38702.1 - 0.015 13.8 21.1 0.017 13.6 21.1 1.0 1 0 0 1 1 1 0 Mpp10 protein DUF4471 PF14740.6 KXH38702.1 - 0.026 13.8 3.5 0.033 13.4 3.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4471) RR_TM4-6 PF06459.12 KXH38702.1 - 0.065 13.1 15.8 0.072 12.9 15.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.14 KXH38702.1 - 0.16 10.2 14.9 0.16 10.2 14.9 1.0 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 KXH38702.1 - 0.2 9.8 22.6 0.21 9.7 22.6 1.0 1 0 0 1 1 1 0 Nop14-like family DUF2457 PF10446.9 KXH38702.1 - 0.27 10.3 23.1 0.29 10.3 23.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DDHD PF02862.17 KXH38702.1 - 0.28 11.3 2.1 0.27 11.4 2.1 1.1 1 0 0 1 1 1 0 DDHD domain SpoIIP PF07454.11 KXH38702.1 - 0.56 9.6 11.1 0.62 9.5 11.1 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF2052 PF09747.9 KXH38702.1 - 0.72 10.0 24.2 1.1 9.4 24.2 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) SDA1 PF05285.12 KXH38702.1 - 0.91 8.9 24.5 1.1 8.7 24.5 1.1 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 KXH38702.1 - 0.93 8.8 21.9 1.1 8.6 21.9 1.0 1 0 0 1 1 1 0 BUD22 NPR3 PF03666.13 KXH38702.1 - 1 8.1 7.0 1.2 7.8 7.0 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CPSF100_C PF13299.6 KXH38702.1 - 1.2 9.4 10.2 1.6 8.9 10.2 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal RXT2_N PF08595.11 KXH38702.1 - 1.2 9.2 10.2 1.5 8.8 10.2 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal Neur_chan_memb PF02932.16 KXH38702.1 - 1.4 8.9 6.0 1.6 8.7 6.0 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Tim54 PF11711.8 KXH38702.1 - 1.5 7.5 14.2 1.7 7.3 14.2 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF4820 PF16091.5 KXH38702.1 - 1.6 8.0 13.2 2.4 7.5 13.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) DUF4045 PF13254.6 KXH38702.1 - 1.7 8.2 11.4 1.8 8.1 11.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) DUF5523 PF17661.1 KXH38702.1 - 2.1 8.0 21.4 2.4 7.8 21.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5523) DNA_pol_phi PF04931.13 KXH38702.1 - 2.1 6.4 28.2 2.3 6.2 28.2 1.0 1 0 0 1 1 1 0 DNA polymerase phi DUF913 PF06025.12 KXH38702.1 - 2.2 7.1 9.4 2.4 7.1 9.4 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Presenilin PF01080.17 KXH38702.1 - 2.4 6.8 11.7 2.8 6.6 11.7 1.0 1 0 0 1 1 1 0 Presenilin LAP1C PF05609.12 KXH38702.1 - 2.5 7.1 13.3 2.7 7.0 13.3 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) SAPS PF04499.15 KXH38702.1 - 2.6 6.7 9.3 2.8 6.6 9.3 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Paf1 PF03985.13 KXH38702.1 - 2.9 6.8 23.3 3.3 6.6 23.3 1.2 1 0 0 1 1 1 0 Paf1 RRN3 PF05327.11 KXH38702.1 - 3.3 6.1 12.8 3.9 5.9 12.8 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF2722 PF10846.8 KXH38702.1 - 4 6.3 10.8 4.4 6.1 10.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) CobT PF06213.12 KXH38702.1 - 4.2 6.7 23.4 5 6.4 23.4 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Hid1 PF12722.7 KXH38702.1 - 5 5.1 7.1 5 5.1 7.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SLC12 PF03522.15 KXH38702.1 - 5.1 6.0 6.5 5.4 5.9 6.5 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Sec62 PF03839.16 KXH38702.1 - 6.1 6.3 8.2 7.2 6.1 8.2 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 Sporozoite_P67 PF05642.11 KXH38702.1 - 8.1 4.4 11.3 8.3 4.4 11.3 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen IFT57 PF10498.9 KXH38702.1 - 8.2 5.3 18.0 9.4 5.1 18.0 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 PI3K_1B_p101 PF10486.9 KXH38702.1 - 8.3 4.0 10.7 9.4 3.9 10.7 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit HSP70 PF00012.20 KXH38702.1 - 9.8 4.2 13.7 11 4.1 13.7 1.0 1 0 0 1 1 1 0 Hsp70 protein ALMT PF11744.8 KXH38702.1 - 9.9 4.9 6.1 12 4.6 6.1 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Vps36_ESCRT-II PF11605.8 KXH38703.1 - 0.029 14.6 0.0 0.081 13.1 0.0 1.7 1 1 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 RraA-like PF03737.15 KXH38704.1 - 8.7e-26 90.9 0.2 1.1e-25 90.6 0.2 1.1 1 0 0 1 1 1 1 Aldolase/RraA Drf_GBD PF06371.13 KXH38705.1 - 1.6e-15 57.2 1.3 3.8e-14 52.7 1.3 2.3 1 1 0 1 1 1 1 Diaphanous GTPase-binding Domain Suc_Fer-like PF06999.12 KXH38706.1 - 4e-72 242.2 0.0 4.6e-72 242.0 0.0 1.0 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Acyltransferase PF01553.21 KXH38707.1 - 1e-10 41.4 0.0 1.3e-05 24.9 0.0 2.3 2 0 0 2 2 2 2 Acyltransferase ABC2_membrane_4 PF12730.7 KXH38707.1 - 0.57 10.1 4.1 3 7.8 0.6 2.4 2 0 0 2 2 2 0 ABC-2 family transporter protein NTP_transf_6 PF06042.11 KXH38708.1 - 3e-51 173.4 0.0 3.6e-51 173.2 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyltransferase AP_endonuc_2 PF01261.24 KXH38709.1 - 7.1e-39 133.4 0.0 8.8e-39 133.1 0.0 1.1 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Anoctamin PF04547.12 KXH38710.1 - 2.2e-105 353.1 2.3 2.7e-105 352.8 2.3 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel DUF4395 PF14340.6 KXH38710.1 - 0.13 12.6 2.3 0.31 11.4 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4395) adh_short PF00106.25 KXH38711.1 - 5.9e-07 29.1 0.0 3.2e-06 26.8 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXH38711.1 - 0.00012 21.7 0.0 0.00021 21.0 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH38711.1 - 0.0047 16.9 0.1 0.011 15.6 0.1 1.7 1 1 0 1 1 1 1 KR domain ApbA PF02558.16 KXH38711.1 - 0.029 14.0 0.0 0.096 12.3 0.0 1.9 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA UPF0731 PF14982.6 KXH38711.1 - 0.11 12.7 0.0 0.29 11.3 0.0 1.7 1 0 0 1 1 1 0 UPF0731 family Ldh_1_N PF00056.23 KXH38711.1 - 0.12 12.5 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Fungal_trans PF04082.18 KXH38712.1 - 8.4e-15 54.5 3.1 1.4e-14 53.8 3.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain FAD_binding_3 PF01494.19 KXH38713.1 - 6.6e-16 58.5 6.4 1.2e-13 51.0 6.4 3.0 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KXH38713.1 - 0.00029 20.5 1.3 0.0021 17.7 0.3 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXH38713.1 - 0.041 14.1 0.0 0.12 12.7 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 KXH38713.1 - 0.11 11.4 0.0 3.2 6.5 0.0 2.3 2 0 0 2 2 2 0 Tryptophan halogenase GF_recep_IV PF14843.6 KXH38713.1 - 0.15 11.8 0.2 0.54 10.1 0.1 1.8 2 0 0 2 2 2 0 Growth factor receptor domain IV MFS_1 PF07690.16 KXH38714.1 - 4.8e-26 91.5 40.7 4.8e-26 91.5 40.7 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Pox_G9-A16 PF03003.16 KXH38715.1 - 0.018 14.8 0.3 1.8 8.3 0.0 2.1 2 0 0 2 2 2 0 Pox virus entry-fusion-complex G9/A16 Flavokinase PF01687.17 KXH38716.1 - 1.3e-11 44.8 0.0 2.5e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 Riboflavin kinase p450 PF00067.22 KXH38717.1 - 2.6e-77 260.5 0.0 3.1e-77 260.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 KXH38718.1 - 2.6e-37 128.6 37.0 2.6e-37 128.6 37.0 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily FMO-like PF00743.19 KXH38718.1 - 3e-31 108.5 0.0 5.3e-15 54.8 0.0 3.1 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KXH38718.1 - 5.9e-12 45.5 0.1 4.5e-07 29.4 0.0 3.1 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Sugar_tr PF00083.24 KXH38718.1 - 1.2e-08 34.3 26.9 3.4e-08 32.8 26.9 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter Pyr_redox_2 PF07992.14 KXH38718.1 - 1.8e-07 30.7 0.0 6.8e-07 28.8 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase MFS_4 PF06779.14 KXH38718.1 - 0.00057 19.3 12.8 0.0027 17.1 5.1 2.2 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB K_oxygenase PF13434.6 KXH38718.1 - 0.00071 18.8 0.0 0.73 8.9 0.0 3.2 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KXH38718.1 - 0.0012 18.8 0.0 0.053 13.5 0.0 3.1 3 0 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KXH38718.1 - 0.003 17.7 0.0 0.0078 16.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXH38718.1 - 0.035 13.7 0.0 1.7 8.2 0.0 3.1 4 0 0 4 4 4 0 FAD dependent oxidoreductase 2OG-FeII_Oxy PF03171.20 KXH38719.1 - 2.8e-14 53.4 0.0 5e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 KXH38719.1 - 4.1e-14 53.4 0.3 9.8e-14 52.1 0.0 1.7 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal AAA_5 PF07728.14 KXH38719.1 - 0.14 12.1 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF1213 PF06740.12 KXH38720.1 - 0.16 12.5 0.9 0.16 12.5 0.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1213) DUF834 PF05754.14 KXH38749.1 - 0.086 12.9 0.1 0.15 12.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF834) Zn_clus PF00172.18 KXH38750.1 - 6.7e-08 32.5 11.1 1.1e-07 31.9 11.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KXH38750.1 - 2.6e-07 29.8 0.3 4.4e-07 29.1 0.3 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain adh_short_C2 PF13561.6 KXH38751.1 - 9.2e-22 77.7 0.0 1.3e-21 77.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXH38751.1 - 1e-12 48.0 0.0 3.3e-12 46.3 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXH38751.1 - 0.0047 16.9 0.0 0.0064 16.4 0.0 1.2 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.8 KXH38751.1 - 0.0073 16.0 0.1 0.012 15.3 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase EF-hand_1 PF00036.32 KXH38752.1 - 3.3e-12 45.0 5.7 3.7e-05 23.0 0.5 4.3 4 0 0 4 4 4 2 EF hand ZZ PF00569.17 KXH38752.1 - 4.1e-10 39.3 7.3 6.9e-10 38.6 7.3 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type EF-hand_6 PF13405.6 KXH38752.1 - 3.6e-08 32.7 5.3 0.00069 19.4 0.4 4.4 4 0 0 4 4 4 2 EF-hand domain EF-hand_7 PF13499.6 KXH38752.1 - 7.5e-07 29.5 10.5 0.003 18.0 0.4 4.1 3 1 0 4 4 4 3 EF-hand domain pair EF-hand_8 PF13833.6 KXH38752.1 - 0.0036 17.1 5.6 0.84 9.5 0.1 3.4 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_4 PF12763.7 KXH38752.1 - 0.019 14.9 0.1 0.16 11.9 0.0 2.5 2 1 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand C1_2 PF03107.16 KXH38752.1 - 0.09 13.1 9.4 0.16 12.3 9.4 1.4 1 0 0 1 1 1 0 C1 domain Dockerin_1 PF00404.18 KXH38752.1 - 0.091 13.0 0.2 0.33 11.2 0.0 2.0 2 0 0 2 2 2 0 Dockerin type I domain EF-hand_5 PF13202.6 KXH38752.1 - 1.4 8.6 10.0 1.3 8.6 0.7 3.5 3 0 0 3 3 3 0 EF hand Abhydrolase_1 PF00561.20 KXH38753.1 - 1.5e-11 44.5 0.1 1.2e-10 41.4 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXH38753.1 - 4.7e-11 42.4 0.1 3e-10 39.8 0.1 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KXH38753.1 - 6.9e-11 43.2 0.2 1.2e-10 42.4 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 KXH38753.1 - 0.0022 17.7 0.0 0.0049 16.5 0.0 1.6 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 KXH38753.1 - 0.057 12.9 0.0 0.2 11.1 0.0 1.9 2 0 0 2 2 2 0 Prolyl oligopeptidase family Esterase_phd PF10503.9 KXH38753.1 - 0.086 12.3 0.1 0.4 10.1 0.0 1.9 2 0 0 2 2 2 0 Esterase PHB depolymerase NMT_C PF02799.15 KXH38754.1 - 7.9e-84 280.4 0.0 1.2e-83 279.8 0.0 1.2 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.19 KXH38754.1 - 1.2e-72 243.0 0.5 8.9e-72 240.1 0.0 2.0 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_9 PF13527.7 KXH38754.1 - 0.00011 22.3 0.2 0.007 16.4 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXH38754.1 - 0.011 15.9 0.0 0.027 14.7 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family DUF1576 PF07613.11 KXH38754.1 - 0.029 13.9 0.0 3.9 7.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1576) DUF3024 PF11225.8 KXH38754.1 - 0.11 12.8 0.0 0.24 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3024) DUF4598 PF15370.6 KXH38754.1 - 0.45 11.0 5.2 2 8.9 5.2 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4598) Abhydrolase_6 PF12697.7 KXH38755.1 - 2.8e-11 44.4 0.5 2.8e-11 44.4 0.5 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXH38755.1 - 3.7e-08 32.9 0.0 5.5e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KXH38755.1 - 4.2e-08 33.2 0.1 6.1e-08 32.6 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 KXH38755.1 - 0.0073 15.9 0.2 0.016 14.8 0.2 1.5 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Tfb2_C PF18307.1 KXH38755.1 - 0.054 13.9 0.1 28 5.2 0.0 3.2 3 0 0 3 3 3 0 Transcription factor Tfb2 (p52) C-terminal domain Abhydrolase_3 PF07859.13 KXH38755.1 - 0.062 13.1 0.1 0.097 12.5 0.1 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold AXE1 PF05448.12 KXH38755.1 - 0.24 10.0 0.3 0.53 8.9 0.2 1.5 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) TMEM171 PF15471.6 KXH38757.1 - 0.78 8.7 3.2 10 5.0 0.3 2.1 2 0 0 2 2 2 0 Transmembrane protein family 171 Mito_fiss_reg PF05308.11 KXH38757.1 - 1.2 9.1 6.9 4.3 7.3 0.3 2.2 2 0 0 2 2 2 0 Mitochondrial fission regulator TLD PF07534.16 KXH38758.1 - 4.9e-30 104.6 0.0 1.5e-29 103.0 0.0 1.8 2 1 0 2 2 2 1 TLD DUF1773 PF08593.10 KXH38758.1 - 1.3e-17 64.5 0.2 4.5e-17 62.8 0.2 2.0 1 0 0 1 1 1 1 Domain of unknown function HIG_1_N PF04588.13 KXH38759.1 - 6e-21 74.4 0.7 6e-21 74.4 0.7 1.7 2 0 0 2 2 2 1 Hypoxia induced protein conserved region PALP PF00291.25 KXH38760.1 - 1.7e-77 260.7 0.8 2.1e-77 260.4 0.8 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 KXH38760.1 - 2.8e-41 139.2 0.0 1.8e-20 72.5 0.0 2.3 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase Complex1_LYR PF05347.15 KXH38761.1 - 1.1e-20 73.5 0.2 1.6e-20 72.9 0.2 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KXH38761.1 - 9.6e-08 32.7 0.0 1.3e-07 32.3 0.0 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Acetyltransf_1 PF00583.25 KXH38762.1 - 9.8e-14 51.6 0.0 1.5e-13 51.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXH38762.1 - 1.2e-08 35.2 0.0 1.9e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KXH38762.1 - 1.2e-06 28.5 0.0 1.9e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KXH38762.1 - 0.00029 21.5 0.0 0.00037 21.2 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXH38762.1 - 0.00034 20.5 0.0 0.00068 19.5 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 KXH38762.1 - 0.0022 18.2 0.0 0.0034 17.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KXH38762.1 - 0.059 13.5 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase PLAC8 PF04749.17 KXH38763.1 - 4e-24 85.5 11.8 5.4e-24 85.1 11.8 1.2 1 0 0 1 1 1 1 PLAC8 family TFIIA PF03153.13 KXH38763.1 - 0.3 11.0 19.3 0.38 10.7 19.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF456 PF04306.13 KXH38764.1 - 0.0042 17.4 1.7 0.0076 16.5 1.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF456) MscS_TM PF12794.7 KXH38764.1 - 0.24 10.2 0.0 0.29 9.9 0.0 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 LapA_dom PF06305.11 KXH38764.1 - 0.25 11.2 0.6 0.49 10.2 0.6 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain DUF3632 PF12311.8 KXH38767.1 - 6.4e-11 43.0 4.1 1.3e-10 41.9 4.1 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3632) p450 PF00067.22 KXH38769.1 - 4.3e-64 217.0 0.0 5.3e-64 216.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ferric_reduct PF01794.19 KXH38770.1 - 3.4e-23 82.1 15.7 3.4e-23 82.1 15.7 2.0 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KXH38771.1 - 1.2e-16 61.2 0.0 2e-15 57.3 0.0 2.1 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KXH38771.1 - 1.1e-10 41.6 0.0 5.9e-07 29.5 0.1 2.3 2 0 0 2 2 2 2 FAD-binding domain NAD_binding_1 PF00175.21 KXH38771.1 - 0.054 14.1 0.0 0.45 11.2 0.0 2.2 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain GFA PF04828.14 KXH38772.1 - 9e-11 42.0 1.0 1.1e-10 41.8 0.2 1.6 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme D_CNTX PF17492.2 KXH38772.1 - 0.11 12.7 0.1 0.11 12.7 0.1 2.4 2 1 0 2 2 2 0 Delta Ctenitoxins Glyco_trans_2_3 PF13632.6 KXH38774.1 - 7.3e-19 68.5 0.1 7.3e-19 68.5 0.1 2.4 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KXH38774.1 - 8.8e-18 65.0 0.0 1.4e-17 64.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KXH38774.1 - 1.2e-12 47.9 0.0 2.3e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 KXH38774.1 - 2.9e-12 46.4 0.0 4.6e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Cellulose_synt PF03552.14 KXH38774.1 - 1.5e-11 43.6 6.1 8e-09 34.6 0.1 3.6 3 1 2 5 5 5 2 Cellulose synthase PEX11 PF05648.14 KXH38774.1 - 0.16 11.5 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) Glyco_hydro_12 PF01670.16 KXH38775.1 - 3.7e-21 76.1 8.3 5.9e-16 59.1 2.8 2.1 1 1 1 2 2 2 2 Glycosyl hydrolase family 12 Macoilin PF09726.9 KXH38776.1 - 2.4 6.6 9.5 2.6 6.5 9.5 1.1 1 0 0 1 1 1 0 Macoilin family TrkH PF02386.16 KXH38777.1 - 1.9e-98 330.1 7.3 1e-96 324.4 0.7 2.0 2 0 0 2 2 2 2 Cation transport protein DUF5345 PF17280.2 KXH38777.1 - 0.07 13.1 0.1 0.07 13.1 0.1 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5345) OTT_1508_deam PF14441.6 KXH38778.1 - 1.8e-19 69.5 0.3 2.4e-18 65.9 0.2 2.6 2 0 0 2 2 2 1 OTT_1508-like deaminase RecO_C PF02565.15 KXH38778.1 - 0.064 13.1 0.0 0.21 11.3 0.0 1.9 2 0 0 2 2 2 0 Recombination protein O C terminal Polysacc_deac_1 PF01522.21 KXH38779.1 - 5e-15 55.5 0.0 9.7e-15 54.6 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase CIA30 PF08547.12 KXH38779.1 - 8.7e-05 22.6 0.0 0.29 11.2 0.0 2.5 2 0 0 2 2 2 2 Complex I intermediate-associated protein 30 (CIA30) Endotoxin_C PF03944.14 KXH38779.1 - 0.0044 17.4 0.9 0.71 10.2 0.2 3.0 3 0 0 3 3 3 1 delta endotoxin Exop_C PF18559.1 KXH38779.1 - 0.0062 16.4 0.0 0.027 14.3 0.0 2.0 2 0 0 2 2 2 1 Galactose-binding domain-like SGBP_B_XBD PF18329.1 KXH38779.1 - 0.0066 16.4 0.4 0.023 14.7 0.4 2.0 1 0 0 1 1 1 1 Surface glycan-binding protein B xyloglucan binding domain DUF2334 PF10096.9 KXH38779.1 - 0.15 11.7 0.0 0.32 10.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) DLH PF01738.18 KXH38780.1 - 0.0011 18.6 0.0 0.0063 16.1 0.0 2.1 2 1 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S15 PF02129.18 KXH38780.1 - 0.0026 17.4 0.1 0.0038 16.9 0.1 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) DUF1100 PF06500.11 KXH38780.1 - 0.0034 16.2 0.0 0.0052 15.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) AXE1 PF05448.12 KXH38780.1 - 0.0042 15.8 0.0 0.022 13.5 0.0 1.8 1 1 1 2 2 2 1 Acetyl xylan esterase (AXE1) BAAT_C PF08840.11 KXH38780.1 - 0.076 12.9 0.0 0.26 11.2 0.0 1.9 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Chlorophyllase2 PF12740.7 KXH38780.1 - 0.12 11.3 0.0 3.5 6.5 0.0 2.2 2 0 0 2 2 2 0 Chlorophyllase enzyme Apolipoprotein PF01442.18 KXH38781.1 - 0.00014 21.8 13.0 0.019 14.9 8.8 3.4 2 1 0 2 2 2 1 Apolipoprotein A1/A4/E domain Plasmodium_Vir PF05795.11 KXH38781.1 - 0.01 15.3 0.0 0.01 15.3 0.0 2.8 3 1 0 3 3 3 0 Plasmodium vivax Vir protein DUF2935 PF11155.8 KXH38781.1 - 0.24 11.8 1.5 33 4.8 0.0 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF2935) DUF883 PF05957.13 KXH38781.1 - 0.26 11.9 18.2 19 6.0 0.0 5.8 3 1 3 6 6 6 0 Bacterial protein of unknown function (DUF883) Phasin PF05597.11 KXH38781.1 - 0.4 10.7 23.4 1.4 8.9 2.1 4.9 2 1 2 5 5 5 0 Poly(hydroxyalcanoate) granule associated protein (phasin) CotJB PF12652.7 KXH38781.1 - 0.48 10.7 3.0 39 4.6 0.0 3.5 3 0 0 3 3 3 0 CotJB protein Senescence PF06911.12 KXH38781.1 - 0.67 10.2 7.2 5 7.4 0.0 3.3 3 2 0 3 3 3 0 Senescence-associated protein YtxH PF12732.7 KXH38781.1 - 0.81 10.3 0.1 0.81 10.3 0.1 6.7 3 2 2 5 5 5 0 YtxH-like protein Peptidase_C65 PF10275.9 KXH38781.1 - 2.9 7.3 5.8 5.5 6.4 0.1 3.2 3 1 0 3 3 3 0 Peptidase C65 Otubain CarD_CdnL_TRCF PF02559.16 KXH38781.1 - 4.9 7.9 17.8 3.4 8.4 1.8 5.0 4 1 1 5 5 5 0 CarD-like/TRCF domain Lactamase_B PF00753.27 KXH38782.1 - 2.2e-22 80.1 1.4 3.5e-22 79.4 1.4 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KXH38782.1 - 1.1e-06 28.3 0.0 1.6e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain CMD PF02627.20 KXH38783.1 - 3.1e-18 65.6 0.2 4.9e-18 65.0 0.2 1.3 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family Fungal_trans PF04082.18 KXH38784.1 - 5.9e-11 41.9 0.1 8e-11 41.5 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain NICE-3 PF07406.11 KXH38784.1 - 0.077 13.0 0.1 0.13 12.3 0.1 1.3 1 0 0 1 1 1 0 NICE-3 protein DUF3070 PF11270.8 KXH38784.1 - 0.15 12.3 0.2 0.39 11.0 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3070) HsbA PF12296.8 KXH38786.1 - 1.8e-14 54.2 3.0 3e-14 53.5 3.0 1.4 1 0 0 1 1 1 1 Hydrophobic surface binding protein A OTT_1508_deam PF14441.6 KXH38787.1 - 1.6e-05 24.8 0.1 0.056 13.5 0.0 2.5 1 1 1 2 2 2 2 OTT_1508-like deaminase Tannase PF07519.11 KXH38789.1 - 7.5e-96 321.9 2.2 9e-96 321.6 2.2 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase IMS PF00817.20 KXH38790.1 - 5.1e-43 146.6 0.2 1e-42 145.7 0.2 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 KXH38790.1 - 3.3e-14 53.6 0.6 9.6e-14 52.1 0.0 2.0 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 KXH38790.1 - 0.0022 18.2 0.1 0.0051 17.1 0.1 1.7 1 0 0 1 1 1 1 IMS family HHH motif Arg_repressor PF01316.21 KXH38790.1 - 0.16 11.7 2.6 0.43 10.4 2.6 1.6 1 0 0 1 1 1 0 Arginine repressor, DNA binding domain RGS PF00615.19 KXH38791.1 - 5.2e-06 26.7 0.0 1.5e-05 25.3 0.0 1.7 1 1 0 1 1 1 1 Regulator of G protein signaling domain Oxidored_q3 PF00499.20 KXH38791.1 - 0.0093 15.7 1.9 0.0093 15.7 1.9 1.7 1 1 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 p450 PF00067.22 KXH38792.1 - 1.4e-37 129.5 0.0 1.2e-23 83.6 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 PDGLE PF13190.6 KXH38794.1 - 0.069 13.0 0.1 0.38 10.7 0.0 2.0 2 0 0 2 2 2 0 PDGLE domain DUF2480 PF10652.9 KXH38794.1 - 0.091 12.7 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2480) Peptidase_M61 PF05299.12 KXH38795.1 - 0.019 15.4 0.5 0.19 12.1 0.5 2.2 1 1 0 1 1 1 0 M61 glycyl aminopeptidase PDZ_6 PF17820.1 KXH38795.1 - 0.034 14.0 0.1 0.081 12.8 0.1 1.6 1 0 0 1 1 1 0 PDZ domain DUF3433 PF11915.8 KXH38796.1 - 1.1e-05 25.8 1.8 1.1e-05 25.8 1.8 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3433) DUF3500 PF12006.8 KXH38797.1 - 5.4e-111 370.8 0.0 6.4e-111 370.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3500) FAA_hydrolase PF01557.18 KXH38798.1 - 6.4e-53 179.6 0.0 8.4e-53 179.3 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family RE_HaeIII PF09556.10 KXH38799.1 - 0.021 13.9 0.0 0.023 13.8 0.0 1.0 1 0 0 1 1 1 0 HaeIII restriction endonuclease Lys-AminoMut_A PF09043.11 KXH38799.1 - 0.025 13.0 0.0 0.029 12.9 0.0 1.0 1 0 0 1 1 1 0 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit B12-binding PF02310.19 KXH38799.1 - 0.069 13.2 0.1 0.11 12.6 0.1 1.3 1 0 0 1 1 1 0 B12 binding domain Lant_dehydr_N PF04738.13 KXH38799.1 - 0.08 11.0 0.0 0.083 11.0 0.0 1.0 1 0 0 1 1 1 0 Lantibiotic dehydratase, N terminus FAD_binding_3 PF01494.19 KXH38800.1 - 3.2e-22 79.3 0.0 4.9e-22 78.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KXH38800.1 - 3.9e-12 46.4 1.1 5e-05 23.1 0.0 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXH38800.1 - 7.2e-07 28.7 0.9 0.0013 18.0 0.4 2.3 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXH38800.1 - 4.7e-06 27.1 0.6 0.00066 20.2 0.1 2.8 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXH38800.1 - 6.4e-06 26.3 1.5 1.2e-05 25.5 0.8 1.8 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KXH38800.1 - 5.4e-05 22.5 1.5 9.9e-05 21.6 1.5 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KXH38800.1 - 6.6e-05 21.8 0.7 0.00048 18.9 0.7 2.0 2 0 0 2 2 2 1 HI0933-like protein SE PF08491.10 KXH38800.1 - 0.001 18.2 0.0 0.0024 17.0 0.0 1.6 1 1 0 1 1 1 1 Squalene epoxidase GIDA PF01134.22 KXH38800.1 - 0.001 18.2 0.6 0.0029 16.7 0.8 1.7 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 KXH38800.1 - 0.0014 18.1 1.3 0.002 17.6 1.3 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KXH38800.1 - 0.0085 15.0 0.4 0.075 11.9 0.2 2.3 2 1 1 3 3 3 1 Tryptophan halogenase AlaDh_PNT_C PF01262.21 KXH38800.1 - 0.01 15.1 0.5 0.019 14.3 0.5 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DUF3603 PF12227.8 KXH38800.1 - 0.015 14.6 0.0 0.025 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3603) 3HCDH_N PF02737.18 KXH38800.1 - 0.023 14.6 0.2 0.038 13.9 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.17 KXH38800.1 - 0.032 13.5 0.4 0.051 12.8 0.4 1.2 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.12 KXH38800.1 - 0.033 13.3 0.0 0.054 12.5 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Amino_oxidase PF01593.24 KXH38800.1 - 0.076 12.3 0.4 7.5 5.7 0.0 2.9 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase DUF3533 PF12051.8 KXH38801.1 - 1.7e-119 399.1 12.2 2e-119 398.9 12.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) GWT1 PF06423.12 KXH38801.1 - 0.063 13.4 0.8 2.7 8.1 0.0 3.0 3 0 0 3 3 3 0 GWT1 Phage_holin_1 PF04531.13 KXH38801.1 - 0.068 13.7 0.3 0.24 11.9 0.3 1.9 1 0 0 1 1 1 0 Bacteriophage holin PDR_CDR PF06422.12 KXH38801.1 - 0.64 10.0 0.0 0.64 10.0 0.0 3.0 4 0 0 4 4 4 0 CDR ABC transporter MFS_1 PF07690.16 KXH38802.1 - 7e-34 117.3 33.4 7e-34 117.3 33.4 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily HET PF06985.11 KXH38802.1 - 2.1e-12 47.6 6.8 4.1e-10 40.2 1.4 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) MFS_2 PF13347.6 KXH38802.1 - 5.7e-06 25.2 4.5 9.6e-06 24.4 4.5 1.3 1 0 0 1 1 1 1 MFS/sugar transport protein Adeno_E3_15_3 PF03307.14 KXH38802.1 - 0.089 12.7 0.1 1.9 8.5 0.0 2.3 2 0 0 2 2 2 0 Adenovirus 15.3kD protein in E3 region DUF3292 PF11696.8 KXH38803.1 - 0.14 10.5 5.3 0.14 10.5 5.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) Presenilin PF01080.17 KXH38803.1 - 0.18 10.5 5.4 0.18 10.6 5.4 1.0 1 0 0 1 1 1 0 Presenilin TP53IP5 PF15331.6 KXH38803.1 - 0.19 11.9 7.2 0.22 11.6 7.2 1.0 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 DUF5427 PF10310.9 KXH38803.1 - 0.46 9.4 10.9 0.52 9.2 10.9 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5427) DUF2656 PF10847.8 KXH38803.1 - 0.5 10.5 4.4 0.39 10.8 2.2 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2656) FUSC PF04632.12 KXH38803.1 - 0.95 7.9 5.6 1 7.8 5.6 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family CbtA PF09490.10 KXH38803.1 - 1.7 8.4 5.0 2.2 8.0 5.0 1.4 1 1 0 1 1 1 0 Probable cobalt transporter subunit (CbtA) CENP-U PF13097.6 KXH38803.1 - 1.8 8.5 14.5 2.2 8.2 14.5 1.0 1 0 0 1 1 1 0 CENP-A nucleosome associated complex (NAC) subunit DUF2992 PF11208.8 KXH38803.1 - 2.9 8.1 16.0 3.9 7.7 16.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) Hid1 PF12722.7 KXH38803.1 - 6.5 4.7 7.0 8.6 4.3 7.0 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein BORG_CEP PF14957.6 KXH38803.1 - 7.3 7.8 7.7 9.7 7.4 7.7 1.2 1 0 0 1 1 1 0 Cdc42 effector DUF4337 PF14235.6 KXH38803.1 - 9.1 6.4 14.2 12 6.0 14.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) RTA1 PF04479.13 KXH38804.1 - 2.4e-65 220.0 11.0 2.4e-65 220.0 11.0 1.6 1 1 1 2 2 2 1 RTA1 like protein DUF1600 PF07667.11 KXH38804.1 - 4.8 7.4 9.3 0.3 11.3 0.8 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF1600) Zn_clus PF00172.18 KXH38805.1 - 2.2e-08 34.1 9.3 4.2e-08 33.2 9.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KXH38805.1 - 0.00067 18.6 0.1 0.0011 17.9 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain AJAP1_PANP_C PF15298.6 KXH38806.1 - 0.053 13.7 0.0 0.081 13.1 0.0 1.3 1 0 0 1 1 1 0 AJAP1/PANP C-terminus DUF4448 PF14610.6 KXH38806.1 - 0.072 12.9 0.0 0.13 12.0 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) DUF4381 PF14316.6 KXH38806.1 - 0.091 13.0 0.0 0.12 12.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) CcmD PF04995.14 KXH38806.1 - 0.11 12.6 0.5 0.18 11.9 0.5 1.2 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) gpW PF02831.15 KXH38806.1 - 0.17 11.8 0.2 0.31 11.0 0.2 1.4 1 0 0 1 1 1 0 gpW MDMPI_C PF07398.11 KXH38806.1 - 2.2 9.2 7.9 9.7 7.1 3.8 2.7 1 1 1 2 2 2 0 MDMPI C-terminal domain Frataxin_Cyay PF01491.16 KXH38807.1 - 1.7e-37 127.8 0.0 2.3e-37 127.4 0.0 1.1 1 0 0 1 1 1 1 Frataxin-like domain Clat_adaptor_s PF01217.20 KXH38808.1 - 1.1e-42 145.4 0.0 2.1e-42 144.4 0.0 1.4 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Tenui_NS4 PF03300.13 KXH38809.1 - 0.17 11.3 0.0 0.21 10.9 0.0 1.1 1 0 0 1 1 1 0 Tenuivirus non-structural, movement protein NS4 tRNA-synt_1 PF00133.22 KXH38810.1 - 3.8e-36 124.5 0.0 1.9e-26 92.5 0.0 2.8 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 KXH38810.1 - 3e-15 55.9 0.1 1.7e-08 33.7 0.0 2.8 3 0 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 KXH38810.1 - 6.6e-11 42.4 3.0 8.2e-11 42.1 1.9 1.8 1 1 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 KXH38810.1 - 7.9e-08 32.0 0.0 1.8e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain FAD_binding_3 PF01494.19 KXH38812.1 - 1.5e-16 60.6 0.1 2.1e-15 56.8 0.1 2.3 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KXH38812.1 - 1.2e-05 24.8 0.0 2.3e-05 23.8 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXH38812.1 - 1.9e-05 24.8 0.0 4.4e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 KXH38812.1 - 0.00015 20.8 1.1 0.45 9.3 0.2 3.1 2 1 0 3 3 3 2 Tryptophan halogenase FAD_binding_2 PF00890.24 KXH38812.1 - 0.001 18.3 0.5 0.0021 17.2 0.5 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KXH38812.1 - 0.0011 17.8 0.4 0.0026 16.5 0.2 1.6 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.24 KXH38812.1 - 0.0022 17.6 0.3 0.042 13.4 0.1 2.6 3 0 0 3 3 3 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 KXH38812.1 - 0.0063 15.8 0.1 0.052 12.8 0.0 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase ApbA PF02558.16 KXH38812.1 - 0.022 14.4 0.0 0.039 13.6 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Rossmann-like PF10727.9 KXH38812.1 - 0.044 13.7 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Rossmann-like domain NAD_binding_2 PF03446.15 KXH38812.1 - 0.051 13.7 0.1 0.13 12.4 0.0 1.7 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Pyr_redox PF00070.27 KXH38812.1 - 0.056 14.0 0.3 0.13 12.9 0.3 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 KXH38812.1 - 0.056 12.5 0.0 0.21 10.6 0.0 1.8 2 0 0 2 2 2 0 Squalene epoxidase GIDA PF01134.22 KXH38812.1 - 0.066 12.3 0.1 0.14 11.2 0.1 1.5 1 0 0 1 1 1 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 KXH38812.1 - 0.069 12.4 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 KXH38812.1 - 0.11 12.3 0.1 0.24 11.3 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.6 KXH38812.1 - 0.15 12.0 0.0 0.37 10.8 0.0 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding FAD_oxidored PF12831.7 KXH38812.1 - 0.17 11.2 0.0 0.25 10.7 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KXH38812.1 - 0.17 11.1 0.0 1.3 8.2 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Fungal_trans PF04082.18 KXH38813.1 - 2.4e-07 30.0 0.0 6.3e-07 28.7 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain HET PF06985.11 KXH38815.1 - 1.9e-33 115.9 0.2 2.9e-33 115.3 0.2 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MBD PF01429.19 KXH38815.1 - 0.17 11.6 0.4 2.1 8.1 0.0 2.7 3 0 0 3 3 3 0 Methyl-CpG binding domain ToxB_N PF18224.1 KXH38816.1 - 4.7e-29 100.1 1.5 6e-29 99.8 1.5 1.1 1 0 0 1 1 1 1 ToxB N-terminal domain zf-C2H2 PF00096.26 KXH38817.1 - 0.0064 16.9 9.5 6.7 7.4 0.2 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type MutS_I PF01624.20 KXH38817.1 - 0.013 15.7 0.0 0.023 15.0 0.0 1.4 1 0 0 1 1 1 0 MutS domain I zf-H2C2_2 PF13465.6 KXH38817.1 - 0.11 12.9 8.3 0.39 11.2 0.5 2.7 2 0 0 2 2 2 0 Zinc-finger double domain IBR PF01485.21 KXH38817.1 - 0.22 11.8 6.8 1.4 9.2 0.1 3.1 2 2 0 2 2 2 0 IBR domain, a half RING-finger domain zf-C2H2_4 PF13894.6 KXH38817.1 - 0.35 11.8 10.1 8.4 7.5 0.2 3.8 3 0 0 3 3 3 0 C2H2-type zinc finger FAD_binding_3 PF01494.19 KXH38818.1 - 8.7e-15 54.8 0.1 1.6e-07 30.9 0.1 2.9 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KXH38818.1 - 2.8e-06 27.4 0.0 6.3e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KXH38818.1 - 0.0013 19.3 0.0 0.018 15.6 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXH38818.1 - 0.0051 16.1 0.0 0.4 9.9 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NUC PF18510.1 KXH38818.1 - 0.0055 17.2 0.0 0.0096 16.4 0.0 1.3 1 0 0 1 1 1 1 Nuclease domain DAO PF01266.24 KXH38818.1 - 0.0086 15.7 0.1 0.035 13.7 0.0 1.9 1 1 1 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KXH38818.1 - 0.0089 15.1 0.1 0.017 14.2 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.24 KXH38818.1 - 0.0094 15.3 0.3 1 8.5 0.0 2.5 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase Thi4 PF01946.17 KXH38818.1 - 0.022 14.0 0.0 0.038 13.2 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.14 KXH38818.1 - 0.039 13.2 0.0 0.16 11.1 0.0 1.9 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXH38818.1 - 0.11 12.5 0.1 3.6 7.6 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding TrkA_N PF02254.18 KXH38818.1 - 0.19 12.0 0.0 0.43 10.8 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain Nodulin_late PF07127.11 KXH38819.1 - 0.055 13.8 0.3 0.091 13.1 0.0 1.5 2 0 0 2 2 2 0 Late nodulin protein Peptidase_M43 PF05572.13 KXH38821.1 - 2.5e-13 50.2 0.0 3.5e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 KXH38821.1 - 0.0013 18.9 1.4 0.0023 18.1 1.4 1.7 1 1 0 1 1 1 1 Metallo-peptidase family M12 Metallopep PF12044.8 KXH38821.1 - 0.0016 17.1 0.1 0.0023 16.6 0.1 1.1 1 0 0 1 1 1 1 Putative peptidase family Reprolysin_3 PF13582.6 KXH38821.1 - 0.0033 17.9 0.1 0.015 15.9 0.0 1.9 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KXH38821.1 - 0.0059 16.3 0.1 0.012 15.2 0.1 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 KXH38821.1 - 0.016 15.1 0.0 0.021 14.7 0.0 1.3 1 0 0 1 1 1 0 Matrixin DUF4953 PF16313.5 KXH38821.1 - 0.03 13.5 0.0 0.052 12.8 0.0 1.3 1 0 0 1 1 1 0 Met-zincin Peptidase_M66 PF10462.9 KXH38821.1 - 0.052 12.5 0.1 0.074 12.0 0.1 1.2 1 0 0 1 1 1 0 Peptidase M66 Reprolysin_2 PF13574.6 KXH38821.1 - 0.079 12.8 0.1 0.12 12.2 0.1 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like DUF3455 PF11937.8 KXH38823.1 - 4.1e-31 108.5 0.1 5.2e-31 108.2 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) Pkinase PF00069.25 KXH38824.1 - 4.6e-69 232.7 0.0 5.4e-69 232.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXH38824.1 - 1.1e-31 110.1 0.0 1.5e-31 109.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KXH38824.1 - 0.0088 15.0 0.0 0.016 14.2 0.0 1.4 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KXH38824.1 - 0.042 13.2 0.1 0.085 12.2 0.1 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXH38824.1 - 0.059 13.3 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ion_trans_2 PF07885.16 KXH38825.1 - 0.081 12.9 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Ion channel LMWPc PF01451.21 KXH38826.1 - 1.2e-36 126.2 0.0 1e-22 81.0 0.0 2.0 2 0 0 2 2 2 2 Low molecular weight phosphotyrosine protein phosphatase CFEM PF05730.11 KXH38827.1 - 4.2e-11 42.8 12.0 6.8e-11 42.1 12.0 1.3 1 0 0 1 1 1 1 CFEM domain Herpes_capsid PF06112.11 KXH38827.1 - 4.8 7.2 20.1 6.7 6.7 20.1 1.2 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Sporozoite_P67 PF05642.11 KXH38827.1 - 8 4.4 10.3 8.4 4.3 10.3 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen 4HBT_2 PF13279.6 KXH38828.1 - 8.6e-06 26.2 0.0 1.4e-05 25.6 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily ArabFuran-catal PF09206.11 KXH38829.1 - 6.1e-150 498.9 12.1 1.1e-149 498.1 12.1 1.4 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B, catalytic AbfB PF05270.13 KXH38829.1 - 1.1e-55 187.5 5.5 1.6e-55 186.9 5.5 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B (ABFB) domain MBOAT_2 PF13813.6 KXH38830.1 - 1.2e-07 31.8 5.6 3.1e-07 30.5 5.6 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family DUF3084 PF11283.8 KXH38830.1 - 0.67 10.0 3.2 2.1 8.4 0.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3084) Acetyltransf_7 PF13508.7 KXH38831.1 - 6.3e-09 36.1 0.0 1.2e-08 35.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KXH38831.1 - 9e-09 35.3 0.0 1.7e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXH38831.1 - 1.2e-08 35.2 0.0 2.7e-08 34.1 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 KXH38831.1 - 2.6e-07 30.5 0.0 4.6e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 KXH38831.1 - 6.6e-07 29.5 0.0 1.1e-05 25.6 0.1 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KXH38831.1 - 0.0014 18.7 0.0 0.0058 16.7 0.0 1.9 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase SnoaL_2 PF12680.7 KXH38834.1 - 3.3e-06 27.7 0.0 4.5e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 KXH38834.1 - 0.0022 17.8 0.0 0.26 11.1 0.0 2.2 2 0 0 2 2 2 2 SnoaL-like polyketide cyclase O-FucT PF10250.9 KXH38835.1 - 1.3e-14 54.6 0.0 3.5e-14 53.3 0.0 1.7 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Glyco_hydro_18 PF00704.28 KXH38836.1 - 4.5e-69 233.6 2.9 6.7e-69 233.0 2.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 KXH38836.1 - 1.6e-09 38.1 20.4 1.6e-09 38.1 20.4 4.4 4 0 0 4 4 4 2 Chitin recognition protein LysM PF01476.20 KXH38837.1 - 2.2e-05 24.4 5.1 12 6.1 0.1 6.9 7 0 0 7 7 7 3 LysM domain HTH_Tnp_1 PF01527.20 KXH38837.1 - 0.011 16.1 0.0 1.5e+02 2.8 0.0 4.3 4 0 0 4 4 4 0 Transposase YlqD PF11068.8 KXH38838.1 - 0.0057 17.0 2.3 0.011 16.1 2.3 1.5 1 0 0 1 1 1 1 YlqD protein MFS_1 PF07690.16 KXH38839.1 - 3.2e-38 131.6 30.0 3.2e-38 131.6 30.0 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH38839.1 - 4.4e-14 52.2 7.9 4.4e-14 52.2 7.9 2.7 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KXH38839.1 - 1.3e-09 37.0 2.2 1.3e-09 37.0 2.2 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) FAD_binding_3 PF01494.19 KXH38840.1 - 6.5e-20 71.7 0.0 8.2e-20 71.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KXH38840.1 - 6.2e-08 32.8 2.0 1e-07 32.1 0.7 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KXH38840.1 - 2.6e-07 30.1 1.0 4.5e-07 29.3 0.5 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 KXH38840.1 - 9.6e-07 28.3 0.1 0.00015 21.1 0.2 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXH38840.1 - 1.1e-05 25.3 2.4 0.0039 16.8 2.3 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.14 KXH38840.1 - 4e-05 22.5 0.1 0.0005 18.9 0.2 2.0 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 KXH38840.1 - 0.00011 21.7 0.0 0.00014 21.3 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KXH38840.1 - 0.00015 21.1 0.6 0.00024 20.5 0.6 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KXH38840.1 - 0.00023 20.4 0.2 0.16 11.0 0.0 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox PF00070.27 KXH38840.1 - 0.0017 18.9 0.3 0.011 16.3 0.6 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KXH38840.1 - 0.01 15.0 0.3 0.015 14.4 0.3 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Thi4 PF01946.17 KXH38840.1 - 0.039 13.2 0.2 0.063 12.5 0.2 1.3 1 0 0 1 1 1 0 Thi4 family FMO-like PF00743.19 KXH38840.1 - 0.097 11.1 0.2 0.13 10.6 0.2 1.1 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like FAA_hydrolase PF01557.18 KXH38841.1 - 3e-60 203.6 0.0 3.6e-60 203.3 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Homeobox_KN PF05920.11 KXH38842.1 - 9.6e-16 57.4 3.5 3.6e-15 55.6 3.5 2.1 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 KXH38842.1 - 4.2e-09 36.1 1.0 4.2e-09 36.1 1.0 1.9 2 0 0 2 2 2 1 Homeodomain zf-C2H2_4 PF13894.6 KXH38842.1 - 4e-05 24.1 19.6 0.00089 19.9 1.6 5.5 5 0 0 5 5 5 1 C2H2-type zinc finger zf-C2H2 PF00096.26 KXH38842.1 - 0.0026 18.1 21.6 0.013 15.9 1.6 5.2 5 0 0 5 5 5 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 KXH38842.1 - 0.013 15.7 1.8 0.013 15.7 1.8 2.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding HTH_Tnp_Tc5 PF03221.16 KXH38842.1 - 0.018 15.0 0.0 0.98 9.5 0.0 3.1 2 0 0 2 2 2 0 Tc5 transposase DNA-binding domain zf-C2H2_2 PF12756.7 KXH38842.1 - 0.024 15.0 7.5 10 6.5 2.7 3.4 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) Homez PF11569.8 KXH38842.1 - 0.06 12.8 0.0 0.23 11.0 0.0 2.0 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez zf-C2H2_3rep PF18868.1 KXH38842.1 - 0.21 12.3 5.7 6.9 7.4 0.1 2.7 2 1 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-C2HC_2 PF13913.6 KXH38842.1 - 0.97 9.4 3.1 14 5.8 0.1 3.1 2 0 0 2 2 2 0 zinc-finger of a C2HC-type FAM199X PF15814.5 KXH38842.1 - 2.4 7.1 7.3 6 5.8 7.3 1.6 1 0 0 1 1 1 0 Protein family FAM199X adh_short_C2 PF13561.6 KXH38843.1 - 1.7e-58 197.9 2.5 2e-58 197.7 2.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXH38843.1 - 5.4e-44 150.0 1.6 6.9e-44 149.6 1.6 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXH38843.1 - 2.6e-07 30.8 0.9 3.9e-07 30.1 0.9 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KXH38843.1 - 0.069 12.5 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Acetyltransf_10 PF13673.7 KXH38844.1 - 2.2e-07 30.9 0.0 5.9e-07 29.5 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXH38844.1 - 3.5e-07 30.5 0.0 5.8e-07 29.7 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXH38844.1 - 1.4e-05 25.5 0.0 3.6e-05 24.1 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KXH38844.1 - 0.037 14.7 0.0 0.52 11.0 0.0 2.2 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KXH38844.1 - 0.042 13.9 0.0 0.43 10.7 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain DUF2207 PF09972.9 KXH38845.1 - 0.13 11.0 0.3 0.19 10.4 0.1 1.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF543 PF04418.12 KXH38845.1 - 0.17 11.9 1.0 0.31 11.0 1.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF543) JAB PF01398.21 KXH38847.1 - 4e-14 52.6 0.0 7.8e-14 51.7 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease USP8_dimer PF08969.11 KXH38847.1 - 2.2e-05 24.6 0.0 4.5e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 USP8 dimerisation domain Prok-JAB PF14464.6 KXH38847.1 - 2.3e-05 24.1 0.0 6e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Prefoldin_2 PF01920.20 KXH38849.1 - 2.4e-19 69.2 12.3 3.2e-19 68.8 12.3 1.2 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_3 PF13758.6 KXH38849.1 - 0.0083 16.2 4.2 0.012 15.7 4.2 1.3 1 0 0 1 1 1 1 Prefoldin subunit Terminase_4 PF05119.12 KXH38849.1 - 0.019 15.4 5.7 0.9 10.0 0.7 2.2 2 0 0 2 2 2 0 Phage terminase, small subunit MREG PF15812.5 KXH38849.1 - 0.05 13.9 0.6 0.085 13.2 0.5 1.4 1 1 0 1 1 1 0 Melanoregulin Herpes_BLRF2 PF05812.12 KXH38849.1 - 0.055 13.6 5.1 0.09 12.9 4.7 1.6 1 1 0 1 1 1 0 Herpesvirus BLRF2 protein JIP_LZII PF16471.5 KXH38849.1 - 0.061 13.5 3.0 0.061 13.5 3.0 2.0 2 1 0 2 2 2 0 JNK-interacting protein leucine zipper II Rx_N PF18052.1 KXH38849.1 - 0.073 13.4 8.4 1.5 9.1 3.5 2.2 2 0 0 2 2 2 0 Rx N-terminal domain Spc7 PF08317.11 KXH38849.1 - 0.15 11.0 15.2 0.59 9.0 15.2 1.8 1 1 0 1 1 1 0 Spc7 kinetochore protein PHM7_cyt PF14703.6 KXH38849.1 - 0.23 11.7 7.7 0.52 10.5 7.7 1.6 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter ERp29 PF07749.12 KXH38849.1 - 0.24 12.3 5.2 1.8 9.5 5.2 2.2 1 1 0 1 1 1 0 Endoplasmic reticulum protein ERp29, C-terminal domain DUF4201 PF13870.6 KXH38849.1 - 0.41 10.4 11.0 2.8 7.7 0.3 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4201) Prefoldin PF02996.17 KXH38849.1 - 0.64 9.9 11.2 6.9e+02 0.2 10.9 2.8 1 1 0 1 1 1 0 Prefoldin subunit FlaC_arch PF05377.11 KXH38849.1 - 1.3 9.5 5.5 13 6.2 2.6 3.0 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) TMPIT PF07851.13 KXH38849.1 - 1.3 8.2 6.6 1.6 7.9 6.6 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF4407 PF14362.6 KXH38849.1 - 4.7 6.5 10.9 5.9 6.2 10.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Spc24 PF08286.11 KXH38849.1 - 8 6.8 11.2 5.4 7.3 5.9 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 ABC_tran_CTD PF16326.5 KXH38849.1 - 8.9 6.6 12.8 0.9 9.8 3.4 2.7 2 1 0 2 2 2 0 ABC transporter C-terminal domain AAA PF00004.29 KXH38850.1 - 6.1e-42 143.2 0.0 1.2e-41 142.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 KXH38850.1 - 5.7e-26 90.3 0.2 1.9e-25 88.6 0.1 2.0 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 KXH38850.1 - 6.1e-23 80.7 1.7 1.4e-22 79.5 1.7 1.7 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain AAA_lid_3 PF17862.1 KXH38850.1 - 9.9e-07 28.5 0.0 2.8e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 KXH38850.1 - 1.5e-06 28.0 0.0 2.7e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 KXH38850.1 - 2e-05 24.0 0.0 4.2e-05 22.9 0.0 1.5 1 1 0 1 1 1 1 TIP49 P-loop domain AAA_16 PF13191.6 KXH38850.1 - 2.6e-05 24.7 0.0 0.003 18.0 0.0 2.7 1 1 0 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.17 KXH38850.1 - 3.6e-05 23.6 0.0 6.8e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.22 KXH38850.1 - 0.00011 22.5 0.0 0.016 15.6 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_5 PF07728.14 KXH38850.1 - 0.00012 22.1 0.0 0.00046 20.2 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KXH38850.1 - 0.00019 21.7 0.1 0.025 14.9 0.0 2.7 1 1 1 2 2 2 1 AAA domain AAA_14 PF13173.6 KXH38850.1 - 0.00025 21.1 0.0 0.00059 19.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 KXH38850.1 - 0.00072 18.8 0.0 0.0051 16.0 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 KXH38850.1 - 0.0011 19.5 0.0 0.0034 17.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KXH38850.1 - 0.0034 17.1 0.0 0.009 15.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KXH38850.1 - 0.0039 17.4 0.0 0.009 16.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 KXH38850.1 - 0.0079 16.6 0.0 0.063 13.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.14 KXH38850.1 - 0.014 15.5 0.0 0.051 13.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) NACHT PF05729.12 KXH38850.1 - 0.032 14.1 0.0 0.96 9.3 0.0 2.3 1 1 1 2 2 2 0 NACHT domain Mg_chelatase PF01078.21 KXH38850.1 - 0.038 13.4 0.0 0.1 12.0 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 KXH38850.1 - 0.042 13.4 0.1 0.16 11.5 0.0 2.0 2 1 0 2 2 2 0 P-loop containing dynein motor region AAA_25 PF13481.6 KXH38850.1 - 0.043 13.4 0.1 0.45 10.1 0.1 2.3 1 1 0 2 2 2 0 AAA domain PhoH PF02562.16 KXH38850.1 - 0.076 12.5 0.1 0.19 11.1 0.1 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_21 PF13304.6 KXH38850.1 - 0.1 12.4 0.1 10 5.8 0.0 2.4 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Torsin PF06309.11 KXH38850.1 - 0.12 12.5 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 Torsin Parvo_NS1 PF01057.17 KXH38850.1 - 0.14 11.3 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Cytidylate_kin PF02224.18 KXH38850.1 - 0.17 11.6 0.2 0.67 9.7 0.1 2.1 2 0 0 2 2 2 0 Cytidylate kinase Bac_DnaA PF00308.18 KXH38850.1 - 0.19 11.6 0.0 0.56 10.0 0.0 1.7 1 1 0 1 1 1 0 Bacterial dnaA protein Nop PF01798.18 KXH38851.1 - 2.4e-81 272.6 0.1 2.4e-81 272.6 0.1 1.7 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 KXH38851.1 - 2.4e-17 63.1 0.0 2.4e-17 63.1 0.0 2.5 3 0 0 3 3 3 1 NOP5NT (NUC127) domain RNA_polI_A34 PF08208.11 KXH38851.1 - 0.21 11.6 26.4 0.36 10.9 26.4 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 TRAM_LAG1_CLN8 PF03798.16 KXH38852.1 - 4.1e-35 121.3 19.6 4.1e-35 121.3 19.6 1.6 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 KXH38852.1 - 2.8e-25 87.7 0.0 6.6e-25 86.5 0.0 1.7 1 0 0 1 1 1 1 TRAM1-like protein Glyco_hydro_18 PF00704.28 KXH38853.1 - 7.5e-85 285.4 0.3 9.1e-85 285.1 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF4766 PF15973.5 KXH38853.1 - 0.074 13.6 0.5 0.13 12.8 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4766) ubiquitin PF00240.23 KXH38854.1 - 3.9e-34 116.2 0.6 8e-34 115.2 0.6 1.5 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.19 KXH38854.1 - 2.2e-26 91.7 1.8 2.2e-26 91.7 1.8 2.0 2 0 0 2 2 2 1 Ribosomal protein S27a Rad60-SLD PF11976.8 KXH38854.1 - 2.4e-16 59.3 0.7 5e-16 58.3 0.7 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KXH38854.1 - 2.5e-05 24.6 0.6 0.00013 22.4 0.1 2.2 2 1 0 2 2 2 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 KXH38854.1 - 0.0015 18.6 0.6 0.0034 17.5 0.6 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 KXH38854.1 - 0.0048 17.2 0.9 0.0083 16.5 0.0 1.7 1 1 1 2 2 2 1 Ubiquitin-like domain TBK1_ULD PF18396.1 KXH38854.1 - 0.0055 16.6 0.0 0.0083 16.0 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain DUF2407 PF10302.9 KXH38854.1 - 0.011 16.2 0.8 0.016 15.7 0.8 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 KXH38854.1 - 0.02 14.9 1.0 5.9 7.0 0.2 2.4 2 0 0 2 2 2 0 Ubiquitin-like domain Ribosomal_S26e PF01283.19 KXH38855.1 - 2.6e-52 175.8 9.1 3e-52 175.6 9.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e zf_CopZ PF18423.1 KXH38855.1 - 0.012 15.5 0.4 0.052 13.5 0.0 2.0 2 0 0 2 2 2 0 Zinc binding domain DUF4668 PF15701.5 KXH38855.1 - 0.24 11.2 2.5 0.23 11.3 1.5 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4668) Methyltransf_25 PF13649.6 KXH38856.1 - 1.6e-08 35.1 0.1 3.1e-08 34.2 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH38856.1 - 1.5e-05 25.6 0.1 2.6e-05 24.8 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXH38856.1 - 0.018 14.4 0.0 0.028 13.8 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family p450 PF00067.22 KXH38857.1 - 1.5e-27 96.4 0.0 2.3e-20 72.8 0.0 3.0 1 1 1 2 2 2 2 Cytochrome P450 FluMu_N PF17891.1 KXH38857.1 - 0.13 12.0 0.1 0.33 10.8 0.1 1.6 1 0 0 1 1 1 0 Mu-like prophage FluMu N-terminal domain WH2 PF02205.20 KXH38859.1 - 0.17 11.7 0.2 19 5.3 0.0 2.3 2 0 0 2 2 2 0 WH2 motif Aim21 PF11489.8 KXH38861.1 - 0.018 14.0 0.3 0.021 13.8 0.3 1.0 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 21 Fe-ADH_2 PF13685.6 KXH38861.1 - 0.077 12.7 0.0 0.095 12.4 0.0 1.1 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase Bep_C_terminal PF17841.1 KXH38861.1 - 0.083 13.1 1.5 6.8 7.0 0.2 2.2 2 0 0 2 2 2 0 BID domain of Bartonella effector protein (Bep) RVT_1 PF00078.27 KXH38862.1 - 2.1e-16 60.1 0.0 3.2e-16 59.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SCP_3 PF17844.1 KXH38863.1 - 0.0059 16.4 0.0 0.0093 15.7 0.0 1.3 1 0 0 1 1 1 1 Bacterial SCP ortholog CBM_1 PF00734.18 KXH38864.1 - 9.9e-13 47.8 15.3 3.3e-12 46.1 11.3 2.8 2 0 0 2 2 2 1 Fungal cellulose binding domain Toxin_7 PF05980.12 KXH38864.1 - 0.046 14.0 2.8 0.093 13.0 2.8 1.5 1 0 0 1 1 1 0 Toxin 7 Zincin_1 PF06262.11 KXH38864.1 - 0.12 12.4 0.1 0.34 11.0 0.1 1.7 1 0 0 1 1 1 0 Zincin-like metallopeptidase Peptidase_M66 PF10462.9 KXH38864.1 - 0.66 8.9 5.0 0.16 10.9 0.6 2.0 2 0 0 2 2 2 0 Peptidase M66 Peptidase_M57 PF12388.8 KXH38864.1 - 0.91 9.1 3.0 1.2 8.7 0.1 2.5 2 0 0 2 2 2 0 Dual-action HEIGH metallo-peptidase Mito_fiss_reg PF05308.11 KXH38864.1 - 6.2 6.8 6.3 11 6.1 6.3 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator DUF3824 PF12868.7 KXH38865.1 - 0.77 10.4 18.4 1.2 9.8 18.4 1.4 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) Ank_2 PF12796.7 KXH38867.1 - 5.3e-19 68.6 1.9 1.2e-09 38.6 0.5 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Oxidored_FMN PF00724.20 KXH38867.1 - 3.8e-16 59.3 0.0 7.7e-16 58.3 0.0 1.5 2 0 0 2 2 2 1 NADH:flavin oxidoreductase / NADH oxidase family Ank_5 PF13857.6 KXH38867.1 - 4.8e-15 55.4 7.1 1.1e-06 28.8 0.2 4.5 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXH38867.1 - 1.2e-13 49.9 3.0 0.0025 18.2 0.0 4.8 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.6 KXH38867.1 - 1.1e-12 48.1 3.2 9.6e-06 26.0 0.7 3.3 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KXH38867.1 - 7e-11 42.1 9.5 8.7e-05 22.8 0.1 4.2 4 0 0 4 4 4 3 Ankyrin repeat Methyltranf_PUA PF13636.6 KXH38868.1 - 0.15 12.1 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 RNA-binding PUA-like domain of methyltransferase RsmF HTH_Tnp_Tc5 PF03221.16 KXH38870.1 - 4.9e-11 42.5 0.1 1.6e-10 40.9 0.0 1.9 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 KXH38870.1 - 6.9e-06 25.6 0.0 1.2e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain MarR PF01047.22 KXH38870.1 - 0.00077 19.3 0.1 0.03 14.3 0.0 2.6 2 0 0 2 2 2 1 MarR family HTH_Crp_2 PF13545.6 KXH38870.1 - 0.01 15.8 0.0 0.035 14.1 0.0 1.9 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain HTH_Tnp_4 PF13613.6 KXH38870.1 - 0.012 15.4 0.0 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease HTH_23 PF13384.6 KXH38870.1 - 0.18 11.7 0.0 0.78 9.6 0.0 2.0 2 0 0 2 2 2 0 Homeodomain-like domain PXA PF02194.15 KXH38871.1 - 1e-46 159.2 2.1 3.3e-46 157.6 0.9 2.2 3 0 0 3 3 3 1 PXA domain Nexin_C PF08628.12 KXH38871.1 - 0.001 19.6 0.0 0.0063 17.1 0.0 2.3 2 0 0 2 2 2 1 Sorting nexin C terminal zf-Mss51 PF13824.6 KXH38872.1 - 5.5e-28 96.8 6.5 1.1e-27 95.9 6.5 1.5 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 MMS1_N PF10433.9 KXH38873.1 - 1.4e-159 531.9 0.0 2.8e-159 530.9 0.0 1.5 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 KXH38873.1 - 3.5e-100 335.4 0.0 1.5e-99 333.4 0.0 2.0 2 0 0 2 2 2 1 CPSF A subunit region ANAPC4_WD40 PF12894.7 KXH38873.1 - 0.21 11.9 0.0 4.5 7.6 0.0 3.1 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain UBA_4 PF14555.6 KXH38874.1 - 0.0063 16.3 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 UBA-like domain LysM PF01476.20 KXH38874.1 - 0.012 15.6 0.0 0.02 14.9 0.0 1.3 1 0 0 1 1 1 0 LysM domain zf-RING_6 PF14835.6 KXH38874.1 - 0.026 14.4 1.0 0.052 13.4 1.0 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Prok-RING_4 PF14447.6 KXH38874.1 - 0.081 12.8 8.0 0.18 11.7 8.1 1.6 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 KXH38874.1 - 1.7 8.5 10.2 0.21 11.5 4.3 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXH38874.1 - 9.5 6.6 11.5 23 5.4 11.5 1.7 1 1 0 1 1 1 0 Ring finger domain CBS PF00571.28 KXH38875.1 - 2.8e-07 30.9 0.0 0.17 12.4 0.0 3.1 1 1 1 2 2 2 2 CBS domain Epimerase PF01370.21 KXH38877.1 - 2.9e-20 72.8 0.0 3.9e-20 72.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KXH38877.1 - 1.1e-08 34.5 0.0 1.8e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 KXH38877.1 - 4.5e-07 29.6 0.0 6e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KXH38877.1 - 0.00034 19.7 0.0 0.00093 18.3 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Sacchrp_dh_NADP PF03435.18 KXH38877.1 - 0.0011 19.2 0.0 0.0022 18.3 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain KR PF08659.10 KXH38877.1 - 0.013 15.4 0.0 0.023 14.6 0.0 1.4 1 0 0 1 1 1 0 KR domain TrkA_N PF02254.18 KXH38877.1 - 0.024 14.9 0.0 0.065 13.5 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain F_actin_cap_B PF01115.17 KXH38878.1 - 3.6e-105 350.9 0.0 4.1e-105 350.7 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit BAH PF01426.18 KXH38879.1 - 0.0007 19.5 0.2 0.0023 17.8 0.1 1.9 1 1 1 2 2 2 1 BAH domain PHD PF00628.29 KXH38879.1 - 0.0036 17.2 2.9 0.0097 15.8 2.9 1.7 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 KXH38879.1 - 0.011 15.9 1.9 0.027 14.7 1.9 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain VEGF_C PF14554.6 KXH38879.1 - 0.012 15.7 1.4 0.03 14.4 1.4 1.7 1 0 0 1 1 1 0 VEGF heparin-binding domain FANCL_C PF11793.8 KXH38879.1 - 0.035 14.3 1.7 0.035 14.3 1.7 1.8 2 0 0 2 2 2 0 FANCL C-terminal domain Lipoprotein_20 PF13942.6 KXH38879.1 - 0.072 13.0 0.5 0.65 9.9 0.1 2.1 2 0 0 2 2 2 0 YfhG lipoprotein ATG22 PF11700.8 KXH38880.1 - 6.4e-102 341.6 2.7 7.3e-102 341.4 2.7 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 KXH38880.1 - 6.1e-08 32.0 17.9 0.00013 21.1 3.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily BT1 PF03092.16 KXH38880.1 - 0.008 14.5 0.6 0.015 13.6 0.5 1.4 1 1 0 1 1 1 1 BT1 family CLN3 PF02487.17 KXH38880.1 - 0.042 12.9 0.2 0.068 12.2 0.2 1.3 1 0 0 1 1 1 0 CLN3 protein Cyclin_N PF00134.23 KXH38881.1 - 5.7e-39 132.8 1.1 7.7e-39 132.3 0.2 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KXH38881.1 - 2.9e-12 46.7 0.3 1.5e-11 44.4 0.3 2.2 1 1 0 1 1 1 1 Cyclin, C-terminal domain EFF-AFF PF14884.6 KXH38882.1 - 0.088 10.9 0.1 0.12 10.4 0.0 1.3 1 1 0 1 1 1 0 Type I membrane glycoproteins cell-cell fusogen Amastin PF07344.11 KXH38882.1 - 1.1 9.0 9.1 0.47 10.3 5.8 2.3 2 1 0 2 2 2 0 Amastin surface glycoprotein B-block_TFIIIC PF04182.12 KXH38885.1 - 1.6e-12 47.4 0.0 3.2e-12 46.4 0.0 1.6 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC zf-TFIIB PF13453.6 KXH38885.1 - 0.042 13.2 0.1 0.096 12.0 0.1 1.5 1 0 0 1 1 1 0 Transcription factor zinc-finger UQ_con PF00179.26 KXH38886.1 - 2.5e-18 66.1 0.0 4e-18 65.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KXH38886.1 - 0.089 13.1 0.0 0.2 12.0 0.0 1.6 1 0 0 1 1 1 0 RWD domain CMAS PF02353.20 KXH38888.1 - 4.5e-39 134.4 0.5 6.9e-39 133.8 0.5 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.12 KXH38888.1 - 2.2e-16 60.3 0.0 5.7e-16 58.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH38888.1 - 3.5e-16 59.7 0.0 7.2e-16 58.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH38888.1 - 1e-13 51.3 0.0 1.6e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXH38888.1 - 4.6e-12 46.1 0.0 7e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH38888.1 - 2.1e-10 41.2 0.0 4.2e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXH38888.1 - 4.5e-08 32.7 0.0 7.6e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KXH38888.1 - 2.5e-07 30.4 0.0 4.8e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain DUF938 PF06080.12 KXH38888.1 - 2.5e-05 24.1 0.0 4.4e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF938) TehB PF03848.14 KXH38888.1 - 0.00042 19.8 0.0 0.00069 19.1 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_4 PF02390.17 KXH38888.1 - 0.0016 17.9 0.0 0.0043 16.5 0.0 1.7 2 0 0 2 2 2 1 Putative methyltransferase PCMT PF01135.19 KXH38888.1 - 0.0016 18.2 0.1 0.0037 17.1 0.0 1.7 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltr_RsmB-F PF01189.17 KXH38888.1 - 0.011 15.4 0.0 0.022 14.4 0.0 1.4 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F GidB PF02527.15 KXH38888.1 - 0.017 14.5 0.0 0.031 13.6 0.0 1.4 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G RrnaAD PF00398.20 KXH38888.1 - 0.087 11.9 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase P5-ATPase PF12409.8 KXH38889.1 - 4.4e-39 133.4 1.0 7e-39 132.8 0.0 1.9 2 0 0 2 2 2 1 P5-type ATPase cation transporter E1-E2_ATPase PF00122.20 KXH38889.1 - 5.5e-29 101.0 0.0 1.8e-28 99.3 0.0 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 KXH38889.1 - 6.6e-14 52.7 0.1 2.8e-05 24.5 0.0 3.2 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.21 KXH38889.1 - 3.5e-05 23.6 4.5 3.5e-05 23.6 4.5 1.8 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 KXH38889.1 - 0.012 15.7 0.0 0.026 14.6 0.0 1.5 1 0 0 1 1 1 0 Cation transport ATPase (P-type) Abhydrolase_9_N PF15420.6 KXH38889.1 - 0.077 13.0 1.4 0.13 12.2 0.1 2.1 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus Cation_ATPase_N PF00690.26 KXH38889.1 - 0.11 12.2 0.1 2.3 8.0 0.0 2.5 2 0 0 2 2 2 0 Cation transporter/ATPase, N-terminus SUN PF03856.13 KXH38890.1 - 2e-86 289.4 11.8 2.7e-86 289.0 11.8 1.1 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) TALPID3 PF15324.6 KXH38890.1 - 0.37 8.4 13.3 0.51 7.9 13.3 1.2 1 0 0 1 1 1 0 Hedgehog signalling target DUF908 PF06012.12 KXH38890.1 - 2.9 7.2 3.9 4 6.8 3.9 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) MFS_1 PF07690.16 KXH38891.1 - 3.5e-14 52.5 11.1 3.5e-14 52.5 11.1 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily TMEM208_SND2 PF05620.11 KXH38891.1 - 0.43 10.3 2.4 0.96 9.2 0.2 2.6 3 0 0 3 3 3 0 SRP-independent targeting protein 2/TMEM208 Hist_deacetyl PF00850.19 KXH38892.1 - 9.1e-78 261.8 0.0 1.2e-77 261.4 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain DUF4648 PF15505.6 KXH38892.1 - 0.07 14.0 0.0 0.29 12.0 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4648) UPF0147 PF03685.13 KXH38892.1 - 0.16 12.0 0.0 0.39 10.8 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0147) ING PF12998.7 KXH38893.1 - 5.9e-23 81.4 1.9 8.7e-23 80.8 1.9 1.3 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 KXH38893.1 - 0.00017 21.4 9.1 0.00017 21.4 9.1 1.6 2 0 0 2 2 2 1 PHD-finger zf-RING_2 PF13639.6 KXH38893.1 - 0.48 10.8 6.5 0.95 9.8 6.5 1.5 1 0 0 1 1 1 0 Ring finger domain UDPGP PF01704.18 KXH38894.1 - 4.4e-16 58.6 0.1 7.3e-15 54.5 0.0 2.0 1 1 1 2 2 2 2 UTP--glucose-1-phosphate uridylyltransferase RRM_1 PF00076.22 KXH38990.1 - 2.8e-16 59.1 0.0 6.2e-13 48.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KXH38990.1 - 0.048 13.5 0.0 0.086 12.7 0.0 1.4 1 0 0 1 1 1 0 Occluded RNA-recognition motif RRM_Rrp7 PF17799.1 KXH38990.1 - 0.055 13.3 0.0 0.37 10.6 0.0 2.0 2 0 0 2 2 2 0 Rrp7 RRM-like N-terminal domain LysM PF01476.20 KXH38991.1 - 0.16 12.1 0.0 0.33 11.0 0.0 1.5 1 0 0 1 1 1 0 LysM domain Con-6 PF10346.9 KXH39018.1 - 4.1e-31 106.7 8.1 3.1e-17 62.3 0.2 2.1 2 0 0 2 2 2 2 Conidiation protein 6 DUF1542 PF07564.11 KXH39018.1 - 0.019 15.1 1.6 3.8 7.7 0.3 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1542) Glyco_transf_8C PF08437.10 KXH39018.1 - 0.26 11.4 0.5 23 5.2 0.1 2.1 2 0 0 2 2 2 0 Glycosyl transferase family 8 C-terminal ABC1 PF03109.16 KXH39019.1 - 7.3e-32 110.0 0.0 1.3e-31 109.2 0.0 1.5 1 0 0 1 1 1 1 ABC1 family Pex19 PF04614.12 KXH39021.1 - 2.4e-75 253.5 16.8 2.4e-75 253.5 16.8 2.0 1 1 1 2 2 2 1 Pex19 protein family Cas_Csn2 PF09711.10 KXH39021.1 - 0.13 11.9 0.7 0.96 9.1 0.3 2.1 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Csn2) KIX_2 PF16987.5 KXH39021.1 - 0.37 10.8 5.6 0.15 12.1 0.9 2.5 2 0 0 2 2 2 0 KIX domain ABC_tran_Xtn PF12848.7 KXH39021.1 - 0.52 10.4 7.5 0.33 11.0 1.2 2.8 3 0 0 3 3 3 0 ABC transporter GET2 PF08690.10 KXH39021.1 - 0.54 9.9 21.0 0.033 13.9 8.3 2.5 1 1 1 2 2 2 0 GET complex subunit GET2 CRR7 PF12095.8 KXH39021.1 - 0.71 10.4 4.4 0.84 10.1 0.5 2.5 2 0 0 2 2 2 0 Protein CHLORORESPIRATORY REDUCTION 7 ARL2_Bind_BART PF11527.8 KXH39021.1 - 0.81 9.8 3.9 1.2 9.2 0.1 2.6 2 1 0 2 2 2 0 The ARF-like 2 binding protein BART UQ_con PF00179.26 KXH39022.1 - 2.6e-46 156.7 0.1 3.1e-46 156.5 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KXH39022.1 - 0.029 14.1 0.0 0.034 13.8 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B Asn_synthase PF00733.21 KXH39023.1 - 7.4e-94 315.3 0.0 6e-55 187.3 0.0 2.1 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 KXH39023.1 - 1.2e-40 138.3 0.0 1.9e-40 137.6 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 KXH39023.1 - 1e-30 106.7 0.0 1.9e-30 105.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 KXH39023.1 - 1e-08 34.9 0.0 1.9e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.17 KXH39023.1 - 0.001 18.2 0.0 0.0033 16.6 0.0 1.8 1 1 0 1 1 1 1 NAD synthase Porin_3 PF01459.22 KXH39024.1 - 5.5e-64 216.2 12.5 4e-53 180.6 6.0 2.0 2 0 0 2 2 2 2 Eukaryotic porin OMP_b-brl PF13505.6 KXH39024.1 - 1.5 8.9 16.3 0.73 9.9 8.6 2.5 1 1 0 2 2 2 0 Outer membrane protein beta-barrel domain DnaJ PF00226.31 KXH39025.1 - 1.1e-20 73.5 1.6 1.6e-20 72.9 1.6 1.3 1 0 0 1 1 1 1 DnaJ domain AJAP1_PANP_C PF15298.6 KXH39026.1 - 0.11 12.7 0.5 0.26 11.5 0.5 1.5 1 0 0 1 1 1 0 AJAP1/PANP C-terminus p450 PF00067.22 KXH39027.1 - 2.5e-70 237.5 0.0 3.7e-70 237.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 DUF3989 PF13150.6 KXH39027.1 - 0.056 13.2 0.2 0.27 11.0 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3989) Abhydrolase_6 PF12697.7 KXH39028.1 - 3.9e-18 66.9 0.7 4.7e-18 66.6 0.7 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXH39028.1 - 1.3e-14 54.5 0.2 8.6e-14 51.8 0.2 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXH39028.1 - 6.9e-05 22.2 0.1 0.00012 21.4 0.1 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 KXH39028.1 - 0.0001 21.3 0.0 0.0023 16.9 0.0 2.1 2 0 0 2 2 2 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 KXH39028.1 - 0.00021 20.4 0.0 0.00035 19.7 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase AXE1 PF05448.12 KXH39028.1 - 0.015 14.0 0.0 0.026 13.2 0.0 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Ndr PF03096.14 KXH39028.1 - 0.049 12.3 0.0 0.072 11.8 0.0 1.2 1 0 0 1 1 1 0 Ndr family HTH_23 PF13384.6 KXH39029.1 - 6.4e-05 22.6 0.0 9.2e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Homeodomain-like domain Sigma70_r4 PF04545.16 KXH39029.1 - 0.0017 17.9 0.0 0.0023 17.4 0.0 1.2 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_29 PF13551.6 KXH39029.1 - 0.003 17.6 0.2 0.0052 16.8 0.2 1.5 1 1 0 1 1 1 1 Winged helix-turn helix Sigma70_r4_2 PF08281.12 KXH39029.1 - 0.0066 16.1 0.0 0.0083 15.8 0.0 1.2 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_17 PF12728.7 KXH39029.1 - 0.11 12.7 0.0 0.15 12.3 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_psq PF05225.16 KXH39029.1 - 0.2 11.5 0.0 0.31 10.8 0.0 1.3 1 0 0 1 1 1 0 helix-turn-helix, Psq domain HTH_24 PF13412.6 KXH39029.1 - 0.23 11.1 0.0 0.31 10.6 0.0 1.2 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding AA_permease PF00324.21 KXH39030.1 - 9.3e-106 354.3 42.0 1.1e-105 354.1 42.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KXH39030.1 - 1.1e-26 93.7 46.7 1.3e-26 93.4 46.7 1.1 1 0 0 1 1 1 1 Amino acid permease Aldedh PF00171.22 KXH39031.1 - 4.8e-135 450.6 0.2 5.7e-135 450.4 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KXH39031.1 - 0.1 11.6 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) FMN_dh PF01070.18 KXH39032.1 - 8.3e-120 400.0 0.0 9.6e-120 399.7 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 KXH39032.1 - 2.7e-06 26.6 0.8 8.9e-06 24.9 0.2 1.9 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 KXH39032.1 - 0.00093 18.4 0.0 0.0015 17.8 0.0 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.21 KXH39032.1 - 0.0032 17.0 0.0 0.015 14.7 0.0 2.0 1 1 0 2 2 2 1 Histidine biosynthesis protein ThiG PF05690.14 KXH39032.1 - 0.03 13.6 0.1 0.44 9.8 0.0 2.4 1 1 1 2 2 2 0 Thiazole biosynthesis protein ThiG DHO_dh PF01180.21 KXH39032.1 - 0.082 12.1 0.1 0.12 11.5 0.1 1.3 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase DHDPS PF00701.22 KXH39033.1 - 2.5e-57 193.8 0.0 2.8e-57 193.6 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Fungal_trans_2 PF11951.8 KXH39034.1 - 1.6e-40 139.1 9.3 2.3e-40 138.6 9.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH39034.1 - 2.1e-09 37.3 4.5 3.6e-09 36.6 4.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aminotran_3 PF00202.21 KXH39035.1 - 8.4e-114 380.4 0.0 9.7e-114 380.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aldedh PF00171.22 KXH39036.1 - 4.1e-180 599.2 0.7 4.6e-180 599.1 0.7 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Cyclophil_like PF04126.13 KXH39036.1 - 0.12 12.2 0.2 10 6.0 0.0 2.9 3 0 0 3 3 3 0 Cyclophilin-like DJ-1_PfpI PF01965.24 KXH39037.1 - 1e-16 61.2 0.0 1.4e-16 60.8 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family Amidohydro_3 PF07969.11 KXH39038.1 - 6.3e-69 233.7 0.0 7.1e-69 233.5 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 KXH39038.1 - 2e-15 56.9 0.0 1.7e-11 44.0 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family Anillin PF08174.11 KXH39038.1 - 0.081 13.3 0.0 0.15 12.5 0.0 1.4 1 0 0 1 1 1 0 Cell division protein anillin DSBA PF01323.20 KXH39039.1 - 3.2e-13 49.9 0.2 3.6e-13 49.7 0.2 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Prion PF00377.18 KXH39039.1 - 0.074 12.9 0.2 0.11 12.4 0.2 1.2 1 0 0 1 1 1 0 Prion/Doppel alpha-helical domain Spt5_N PF11942.8 KXH39039.1 - 0.79 10.7 5.1 0.86 10.6 0.5 2.1 1 1 1 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Gln-synt_C PF00120.24 KXH39040.1 - 1.5e-75 254.3 0.0 2.2e-75 253.8 0.0 1.2 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Amidohydro_2 PF04909.14 KXH39040.1 - 2.4e-15 57.1 0.0 5e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 Amidohydrolase HET PF06985.11 KXH39041.1 - 2.9e-25 89.3 0.0 7.7e-25 88.0 0.0 1.8 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Pkinase PF00069.25 KXH39041.1 - 1e-10 41.4 0.0 4.4e-09 36.1 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXH39041.1 - 1.2e-06 28.0 0.0 0.00036 19.9 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXH39042.1 - 4e-14 52.6 0.0 2.9e-11 43.2 0.0 2.5 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXH39042.1 - 4.8e-05 22.8 0.0 0.0002 20.7 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Sep15_SelM PF08806.11 KXH39042.1 - 6.4e-05 23.0 0.2 0.00017 21.7 0.2 1.6 1 0 0 1 1 1 1 Sep15/SelM redox domain Fungal_trans PF04082.18 KXH39043.1 - 8.5e-23 80.7 0.1 1.3e-22 80.1 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH39043.1 - 7.7e-06 25.9 11.7 1.3e-05 25.2 11.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CoA_binding PF02629.19 KXH39044.1 - 7.8e-21 74.6 0.5 7.8e-21 74.6 0.5 2.2 3 0 0 3 3 3 1 CoA binding domain Ligase_CoA PF00549.19 KXH39044.1 - 5.2e-17 62.1 0.2 8.9e-17 61.3 0.2 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 KXH39044.1 - 6e-10 39.1 0.0 9.7e-10 38.4 0.0 1.3 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain GFO_IDH_MocA PF01408.22 KXH39044.1 - 0.0027 18.5 0.0 0.21 12.4 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold Glyco_hydro_43 PF04616.14 KXH39049.1 - 0.00068 19.0 0.4 0.0011 18.4 0.4 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.20 KXH39049.1 - 0.0056 16.3 0.1 0.012 15.2 0.1 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain CDH-cyt PF16010.5 KXH39050.1 - 8.9e-69 230.8 5.9 2e-68 229.7 5.9 1.6 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase GMC_oxred_N PF00732.19 KXH39050.1 - 2.6e-24 86.1 0.0 5.8e-24 85.0 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXH39050.1 - 5.1e-23 82.2 0.2 9.3e-23 81.3 0.2 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KXH39050.1 - 8.1e-10 38.3 0.1 0.00016 20.9 0.1 2.3 2 0 0 2 2 2 2 FAD binding domain CBM_1 PF00734.18 KXH39050.1 - 1.7e-09 37.4 7.3 1.7e-09 37.4 7.3 2.3 2 0 0 2 2 1 1 Fungal cellulose binding domain NAD_binding_8 PF13450.6 KXH39050.1 - 0.00011 22.3 0.1 0.00042 20.5 0.0 2.1 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KXH39050.1 - 0.0011 17.7 0.0 0.0021 16.8 0.0 1.4 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.14 KXH39050.1 - 0.0018 17.6 0.0 0.0041 16.4 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KXH39050.1 - 0.0058 15.7 0.5 0.011 14.8 0.1 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KXH39050.1 - 0.014 14.7 0.2 0.048 12.9 0.5 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KXH39050.1 - 0.021 14.1 0.0 0.034 13.4 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 KXH39050.1 - 0.021 15.4 0.0 0.65 10.6 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KXH39050.1 - 0.023 14.0 0.0 0.3 10.4 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pheromone PF08015.11 KXH39051.1 - 0.11 13.5 1.7 0.24 12.5 1.7 1.6 1 0 0 1 1 1 0 Fungal mating-type pheromone Cu_amine_oxid PF01179.20 KXH39052.1 - 8.4e-130 433.4 9.2 1e-129 433.1 9.2 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain DUF1965 PF09248.10 KXH39052.1 - 1.8e-29 101.3 1.5 5.3e-29 99.8 1.5 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1965) Cu_amine_oxidN2 PF02727.16 KXH39052.1 - 7.3e-06 26.1 0.0 1.9e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Fungal_trans PF04082.18 KXH39053.1 - 2.4e-11 43.2 1.2 4.8e-11 42.2 1.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sugar_tr PF00083.24 KXH39054.1 - 4.3e-88 296.1 9.9 5e-88 295.9 9.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH39054.1 - 3.9e-21 75.4 11.2 3.9e-21 75.4 11.2 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KXH39054.1 - 0.17 10.3 5.8 0.066 11.6 2.5 1.8 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) DUF4149 PF13664.6 KXH39054.1 - 3.5 8.0 8.1 0.54 10.6 0.6 3.3 3 2 0 3 3 3 0 Domain of unknown function (DUF4149) Fungal_trans PF04082.18 KXH39055.1 - 7.5e-12 44.8 0.8 1.6e-11 43.7 0.8 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH39055.1 - 0.0012 18.9 7.2 0.0026 17.9 7.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 KXH39057.1 - 1.7e-33 116.0 45.8 2.8e-32 112.0 31.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily PUCC PF03209.15 KXH39057.1 - 0.00028 20.0 11.1 0.032 13.2 0.8 3.2 2 1 1 3 3 3 3 PUCC protein Aldolase_II PF00596.21 KXH39057.1 - 0.17 11.8 0.0 0.34 10.8 0.0 1.5 1 0 0 1 1 1 0 Class II Aldolase and Adducin N-terminal domain fn3_5 PF06280.12 KXH39058.1 - 6.3e-10 39.7 0.0 1.6e-09 38.5 0.0 1.6 1 0 0 1 1 1 1 Fn3-like domain FlgD_ig PF13860.6 KXH39058.1 - 8.8e-05 22.3 0.0 0.00017 21.4 0.0 1.5 1 0 0 1 1 1 1 FlgD Ig-like domain DUF1735 PF08522.10 KXH39058.1 - 0.14 12.7 0.1 1.3 9.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1735) DUF1593 PF07632.11 KXH39059.1 - 3.1e-78 262.8 0.0 4.2e-78 262.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1593) MFS_1 PF07690.16 KXH39059.1 - 4.7e-27 94.8 61.9 1.5e-26 93.2 45.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_1 PF00232.18 KXH39060.1 - 1.6e-138 461.9 1.8 2e-138 461.6 1.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 NPP1 PF05630.11 KXH39061.1 - 1.3e-41 142.9 0.0 1.7e-41 142.5 0.0 1.2 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) Zn_clus PF00172.18 KXH39063.1 - 2.2e-05 24.5 9.6 6.2e-05 23.0 9.6 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXH39063.1 - 5.1e-05 22.4 0.1 0.00015 20.9 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Peptidase_M24 PF00557.24 KXH39064.1 - 2e-51 174.7 0.0 2.5e-51 174.3 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 KXH39064.1 - 1.2e-22 79.9 0.0 7.1e-22 77.4 0.0 2.0 2 0 0 2 2 2 1 Aminopeptidase P, N-terminal domain MARVEL PF01284.23 KXH39065.1 - 0.0059 16.6 6.0 0.0059 16.6 6.0 2.1 1 1 1 2 2 2 1 Membrane-associating domain DUF2070 PF09843.9 KXH39065.1 - 0.014 13.8 12.3 0.016 13.5 12.3 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF1180 PF06679.12 KXH39065.1 - 0.03 14.7 0.3 0.064 13.7 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) DUF5090 PF17009.5 KXH39065.1 - 0.031 14.2 13.6 0.042 13.8 13.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5090) Polysacc_synt PF01943.17 KXH39065.1 - 0.035 13.5 13.6 0.39 10.1 8.2 2.1 1 1 1 2 2 2 0 Polysaccharide biosynthesis protein DUF485 PF04341.12 KXH39065.1 - 0.046 13.7 1.1 0.046 13.7 1.1 3.0 2 1 0 2 2 2 0 Protein of unknown function, DUF485 Bac_rhodopsin PF01036.18 KXH39065.1 - 0.11 12.1 10.8 0.24 10.9 10.8 1.6 1 1 0 1 1 1 0 Bacteriorhodopsin-like protein COX1 PF00115.20 KXH39065.1 - 0.12 11.1 10.3 0.21 10.4 10.3 1.4 1 1 0 1 1 1 0 Cytochrome C and Quinol oxidase polypeptide I OAD_gamma PF04277.13 KXH39065.1 - 0.51 11.0 6.8 5.6 7.6 0.3 2.5 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain DUF4234 PF14018.6 KXH39065.1 - 0.91 9.7 0.1 0.91 9.7 0.1 3.2 3 1 0 3 3 3 0 Domain of unknown function (DUF4234) MTABC_N PF16185.5 KXH39065.1 - 1.2 8.6 7.4 0.49 9.9 4.6 1.6 1 1 0 1 1 1 0 Mitochondrial ABC-transporter N-terminal five TM region Virul_fac_BrkB PF03631.15 KXH39065.1 - 1.4 8.4 14.8 2 8.0 14.8 1.2 1 0 0 1 1 1 0 Virulence factor BrkB DUF805 PF05656.14 KXH39065.1 - 2.9 8.4 13.2 13 6.3 13.2 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF805) Caps_synth PF05704.12 KXH39066.1 - 1.5e-14 54.0 0.0 2.7e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein Gly_transf_sug PF04488.15 KXH39066.1 - 0.0001 22.8 0.0 0.00027 21.5 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Fungal_trans PF04082.18 KXH39067.1 - 5.8e-12 45.2 0.0 9.6e-12 44.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain FAD_binding_3 PF01494.19 KXH39068.1 - 3.4e-17 62.7 0.0 8e-16 58.2 0.0 2.6 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KXH39068.1 - 1.4e-05 25.2 0.0 4.2e-05 23.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SE PF08491.10 KXH39068.1 - 4.3e-05 22.7 0.0 6.4e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase Pyr_redox_3 PF13738.6 KXH39068.1 - 5.7e-05 22.5 0.0 0.00013 21.4 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXH39068.1 - 0.00015 21.1 0.0 0.00025 20.4 0.0 1.2 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 KXH39068.1 - 0.0033 16.7 0.0 0.006 15.9 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 KXH39068.1 - 0.0069 16.6 0.0 0.018 15.3 0.0 1.7 2 0 0 2 2 2 1 TrkA-N domain DAO PF01266.24 KXH39068.1 - 0.0096 15.5 0.1 0.35 10.4 0.0 2.7 2 1 1 3 3 3 1 FAD dependent oxidoreductase NmrA PF05368.13 KXH39069.1 - 7.3e-13 48.6 0.1 9.7e-13 48.2 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXH39069.1 - 2.3e-12 47.2 0.0 6.2e-12 45.8 0.0 1.7 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KXH39069.1 - 4.9e-09 36.0 0.1 1.7e-06 27.7 0.1 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family KR PF08659.10 KXH39069.1 - 0.00013 21.9 0.1 0.00022 21.2 0.1 1.3 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 KXH39069.1 - 0.00018 21.0 0.1 0.00027 20.4 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXH39069.1 - 0.016 14.7 0.0 0.025 14.1 0.0 1.3 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase TrkA_N PF02254.18 KXH39069.1 - 0.083 13.1 0.4 0.17 12.1 0.1 1.7 2 0 0 2 2 2 0 TrkA-N domain Sugar_tr PF00083.24 KXH39070.1 - 4e-72 243.5 16.4 4.7e-72 243.3 16.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH39070.1 - 5.2e-26 91.4 23.2 1e-25 90.5 15.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KXH39070.1 - 1.4 7.1 14.0 0.044 12.1 0.3 3.0 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Bac_rhamnosid6H PF17389.2 KXH39071.1 - 1.7e-16 60.4 0.1 3e-16 59.6 0.1 1.3 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Glyco_hydro_2_N PF02837.18 KXH39071.1 - 2.2e-05 24.5 0.1 0.0002 21.3 0.0 2.4 3 0 0 3 3 3 1 Glycosyl hydrolases family 2, sugar binding domain Bac_rhamnosid_C PF17390.2 KXH39071.1 - 0.027 14.3 0.0 0.082 12.7 0.0 1.8 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase C-terminal domain Glyco_hydro_36 PF17167.4 KXH39071.1 - 0.14 10.8 0.0 0.22 10.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase 36 superfamily, catalytic domain Glyco_hydro_3_C PF01915.22 KXH39072.1 - 6.9e-66 222.1 0.0 1.3e-65 221.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KXH39072.1 - 2e-47 162.1 0.0 3.4e-47 161.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KXH39072.1 - 4.5e-26 90.8 1.2 1.5e-25 89.0 1.2 2.0 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 KXH39072.1 - 3.8e-12 46.2 0.2 7.7e-12 45.3 0.2 1.4 1 0 0 1 1 1 1 PA14 domain Phage_tail_X PF05489.12 KXH39072.1 - 0.027 14.1 0.1 0.074 12.7 0.1 1.7 1 0 0 1 1 1 0 Phage Tail Protein X Zn_clus PF00172.18 KXH39073.1 - 2e-10 40.6 10.1 2e-10 40.6 10.1 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXH39073.1 - 0.055 12.5 0.1 0.086 11.8 0.1 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain HCO3_cotransp PF00955.21 KXH39074.1 - 3e-70 237.5 17.4 2e-37 129.2 9.4 2.1 1 1 1 2 2 2 2 HCO3- transporter family ABC_tran PF00005.27 KXH39075.1 - 2e-26 93.1 0.0 3.3e-26 92.4 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 KXH39075.1 - 5.9e-14 52.0 7.0 1e-13 51.2 7.0 1.4 1 0 0 1 1 1 1 ABC-2 type transporter RsgA_GTPase PF03193.16 KXH39075.1 - 0.00022 21.2 0.4 0.00047 20.1 0.4 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_21 PF13304.6 KXH39075.1 - 0.0016 18.3 0.2 0.0058 16.5 0.0 1.8 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system MeaB PF03308.16 KXH39075.1 - 0.022 13.7 0.1 0.037 13.0 0.1 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_29 PF13555.6 KXH39075.1 - 0.067 12.9 3.2 0.052 13.3 1.2 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain Dynamin_N PF00350.23 KXH39075.1 - 0.073 13.1 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Dynamin family AAA_25 PF13481.6 KXH39075.1 - 0.11 12.1 0.2 0.44 10.1 0.1 1.9 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KXH39075.1 - 0.11 12.6 0.6 0.22 11.6 0.6 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase Zeta_toxin PF06414.12 KXH39075.1 - 0.11 11.7 0.1 0.25 10.6 0.1 1.5 1 0 0 1 1 1 0 Zeta toxin IIGP PF05049.13 KXH39075.1 - 0.12 11.3 0.2 0.19 10.7 0.2 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) ATPase PF06745.13 KXH39075.1 - 0.16 11.3 0.0 0.37 10.1 0.0 1.5 1 0 0 1 1 1 0 KaiC ABC2_membrane_3 PF12698.7 KXH39075.1 - 0.32 10.0 18.0 0.0082 15.3 11.7 1.5 2 0 0 2 2 2 0 ABC-2 family transporter protein DUF87 PF01935.17 KXH39075.1 - 1.6 8.8 3.2 2.9 7.9 3.2 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain GMC_oxred_N PF00732.19 KXH39076.1 - 2e-51 175.1 0.0 2.9e-51 174.6 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXH39076.1 - 4.9e-29 101.7 0.0 9.7e-29 100.7 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 KXH39076.1 - 1.2e-06 28.3 0.0 2e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KXH39076.1 - 2.1e-05 23.8 0.0 0.027 13.5 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.17 KXH39076.1 - 0.00015 21.1 0.0 0.00026 20.3 0.0 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 KXH39076.1 - 0.001 19.2 0.0 0.0027 17.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KXH39076.1 - 0.0012 18.0 0.0 0.0019 17.3 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KXH39076.1 - 0.0047 16.2 0.0 0.024 13.9 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXH39076.1 - 0.0049 16.9 0.2 0.36 10.8 0.0 2.6 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 KXH39076.1 - 0.0066 15.7 0.0 0.024 13.9 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXH39076.1 - 0.0068 15.2 0.1 0.13 11.0 0.0 2.6 3 0 0 3 3 3 1 HI0933-like protein HHH PF00633.23 KXH39076.1 - 0.36 10.8 1.0 6.5 6.8 0.1 2.6 2 0 0 2 2 2 0 Helix-hairpin-helix motif Amidase PF01425.21 KXH39077.1 - 7.9e-66 222.9 0.2 2.3e-64 218.0 0.0 2.0 2 0 0 2 2 2 2 Amidase P33MONOX PF15302.6 KXH39078.1 - 0.065 12.9 4.6 0.097 12.4 4.6 1.2 1 0 0 1 1 1 0 P33 mono-oxygenase adh_short PF00106.25 KXH39079.1 - 5.6e-24 84.7 1.6 1.1e-13 51.1 0.2 3.3 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXH39079.1 - 4.6e-19 68.9 1.7 3.7e-09 36.5 0.0 3.8 3 1 0 3 3 3 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH39079.1 - 4.5e-05 23.4 0.1 0.00012 22.0 0.0 1.7 2 0 0 2 2 2 1 KR domain AA_permease PF00324.21 KXH39080.1 - 2.5e-119 399.0 33.0 2.8e-119 398.8 33.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KXH39080.1 - 3.4e-25 88.8 35.5 4.5e-25 88.4 35.5 1.0 1 0 0 1 1 1 1 Amino acid permease HMG_box PF00505.19 KXH39081.1 - 0.00087 19.7 4.3 0.5 10.8 0.8 2.5 2 0 0 2 2 2 2 HMG (high mobility group) box DUF3106 PF11304.8 KXH39081.1 - 0.0056 17.1 2.6 2.4 8.6 0.2 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF3106) HMG_box_2 PF09011.10 KXH39081.1 - 0.013 16.1 4.5 0.98 10.1 0.6 2.5 2 0 0 2 2 2 0 HMG-box domain LPD39 PF18858.1 KXH39081.1 - 0.093 12.8 1.2 6.1 6.9 0.4 2.4 2 0 0 2 2 2 0 Large polyvalent protein associated domain 39 adh_short PF00106.25 KXH39082.1 - 3.8e-36 124.4 0.0 8.7e-36 123.2 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXH39082.1 - 5.3e-29 101.4 0.0 1.7e-28 99.7 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH39082.1 - 4.3e-11 43.0 0.8 1.3e-08 35.0 0.1 2.2 2 0 0 2 2 2 2 KR domain Epimerase PF01370.21 KXH39082.1 - 0.0051 16.3 0.0 2.4 7.5 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Fungal_trans PF04082.18 KXH39083.1 - 9e-27 93.8 0.1 1.4e-26 93.1 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain p450 PF00067.22 KXH39084.1 - 2.2e-54 184.9 0.0 2.6e-54 184.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 RolB_RolC PF02027.17 KXH39088.1 - 0.17 11.6 0.0 0.18 11.4 0.0 1.1 1 0 0 1 1 1 0 RolB/RolC glucosidase family Amidohydro_1 PF01979.20 KXH39093.1 - 1.7e-40 139.4 0.0 2e-40 139.2 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KXH39093.1 - 3.6e-16 59.7 1.0 9.9e-10 38.5 0.1 2.5 2 1 0 2 2 2 2 Amidohydrolase family Thioredoxin_2 PF13098.6 KXH39093.1 - 0.017 15.6 0.0 0.034 14.6 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like domain Adeno_E3_14_5 PF04834.12 KXH39094.1 - 0.43 11.2 3.5 9.8 6.8 0.4 2.8 2 1 0 2 2 2 0 Early E3 14.5 kDa protein ATP-grasp_2 PF08442.10 KXH39095.1 - 1.3e-46 158.7 0.0 1.9e-46 158.2 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain SIR2 PF02146.17 KXH39095.1 - 7.7e-35 120.4 0.0 1.3e-33 116.4 0.0 2.2 1 1 0 1 1 1 1 Sir2 family Ligase_CoA PF00549.19 KXH39095.1 - 1.1e-15 57.8 0.5 2.5e-15 56.6 0.5 1.6 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 KXH39095.1 - 1.3e-08 34.6 0.0 2.1e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain HET PF06985.11 KXH39096.1 - 1.6e-19 70.7 0.1 3.6e-19 69.6 0.1 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) adh_short_C2 PF13561.6 KXH39097.1 - 6.2e-64 215.7 0.0 7.6e-64 215.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXH39097.1 - 4.4e-52 176.4 0.0 5.5e-52 176.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXH39097.1 - 1.4e-10 41.3 0.0 2.1e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXH39097.1 - 0.0036 16.8 0.1 0.015 14.7 0.1 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 KXH39097.1 - 0.014 15.3 0.0 0.024 14.5 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 KXH39097.1 - 0.018 15.1 0.1 0.035 14.2 0.1 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain UPF0146 PF03686.13 KXH39097.1 - 0.028 14.3 0.0 0.056 13.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) Polysacc_synt_2 PF02719.15 KXH39097.1 - 0.056 12.6 0.0 0.07 12.2 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 KXH39097.1 - 0.084 11.9 0.0 0.15 11.0 0.0 1.3 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family ADH_N PF08240.12 KXH39098.1 - 1.2e-21 76.6 1.3 1.7e-21 76.1 0.5 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXH39098.1 - 2.5e-21 76.0 0.1 7.5e-21 74.5 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KXH39098.1 - 7.9e-09 35.3 0.0 1.3e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KXH39098.1 - 0.0043 18.1 0.0 0.0096 17.0 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KXH39098.1 - 0.012 14.9 0.2 0.028 13.7 0.2 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain PI-PLC-X PF00388.19 KXH39099.1 - 2.8e-07 30.2 0.0 9.6e-07 28.5 0.0 1.9 1 1 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain DUF166 PF02593.14 KXH39100.1 - 0.052 13.1 0.1 0.073 12.6 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function MACPF PF01823.19 KXH39101.1 - 1.6e-05 25.1 0.1 4.1e-05 23.8 0.0 1.6 1 1 0 1 1 1 1 MAC/Perforin domain But2 PF09792.9 KXH39103.1 - 0.0031 17.9 0.2 0.012 16.0 0.2 1.9 1 1 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain zf-MYND PF01753.18 KXH39104.1 - 2.6e-10 40.2 11.6 3.7e-10 39.7 11.6 1.2 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KXH39104.1 - 0.025 14.9 5.9 0.043 14.1 5.9 1.3 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Glyco_hydro_76 PF03663.14 KXH39105.1 - 1.9e-160 534.4 12.4 2.2e-160 534.2 12.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 KXH39105.1 - 0.015 14.4 9.8 0.11 11.6 0.5 3.2 2 1 1 3 3 3 0 Glycosyl Hydrolase Family 88 2OG-FeII_Oxy_3 PF13640.6 KXH39106.1 - 3.4e-06 27.8 0.0 6.4e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.16 KXH39107.1 - 1e-46 159.5 60.2 1.2e-40 139.6 30.2 2.4 3 0 0 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.13 KXH39107.1 - 4.1e-29 101.5 15.7 2.7e-27 95.5 15.6 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KXH39107.1 - 2e-12 46.8 12.4 2e-12 46.8 12.4 3.0 2 1 1 3 3 3 1 Sugar (and other) transporter MFS_4 PF06779.14 KXH39107.1 - 6.5e-06 25.7 10.9 6.5e-06 25.7 10.9 3.2 2 1 1 3 3 3 1 Uncharacterised MFS-type transporter YbfB MFS_1 PF07690.16 KXH39108.1 - 2.2e-33 115.6 60.1 3.3e-29 101.9 38.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily zf-C2H2 PF00096.26 KXH39109.1 - 0.00011 22.5 13.6 0.069 13.6 2.3 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXH39109.1 - 0.015 16.1 10.7 3.8 8.6 1.3 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger Herpes_BLRF2 PF05812.12 KXH39109.1 - 0.017 15.3 0.2 0.034 14.3 0.2 1.5 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein HIP1_clath_bdg PF16515.5 KXH39109.1 - 0.034 14.8 0.4 0.072 13.7 0.4 1.4 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 zf-C2H2_aberr PF17017.5 KXH39109.1 - 0.045 13.9 0.2 0.64 10.1 0.0 2.2 2 0 0 2 2 2 0 Aberrant zinc-finger FOXP-CC PF16159.5 KXH39109.1 - 0.32 11.7 0.2 0.32 11.7 0.2 3.2 3 1 0 3 3 3 0 FOXP coiled-coil domain Filament PF00038.21 KXH39110.1 - 6.2e-06 26.0 14.7 6.2e-06 26.0 14.7 5.3 3 1 2 5 5 5 1 Intermediate filament protein DUF4407 PF14362.6 KXH39110.1 - 0.0015 18.0 18.3 0.0015 18.0 18.3 4.9 1 1 3 4 4 3 2 Domain of unknown function (DUF4407) Jnk-SapK_ap_N PF09744.9 KXH39110.1 - 0.0035 17.6 7.0 0.0035 17.6 7.0 5.4 4 1 2 6 6 6 1 JNK_SAPK-associated protein-1 BRE1 PF08647.11 KXH39110.1 - 0.0038 17.3 6.0 0.0038 17.3 6.0 6.7 4 2 3 7 7 7 3 BRE1 E3 ubiquitin ligase ADIP PF11559.8 KXH39110.1 - 0.016 15.3 13.3 0.016 15.3 13.3 6.1 5 2 2 7 7 7 0 Afadin- and alpha -actinin-Binding Lzipper-MIP1 PF14389.6 KXH39110.1 - 0.017 15.4 1.4 0.017 15.4 1.4 4.7 2 1 2 4 4 4 0 Leucine-zipper of ternary complex factor MIP1 ZapB PF06005.12 KXH39110.1 - 0.034 14.6 0.4 0.034 14.6 0.4 7.1 6 2 0 6 6 5 0 Cell division protein ZapB TSC22 PF01166.18 KXH39110.1 - 0.076 13.3 0.4 0.076 13.3 0.4 6.1 7 0 0 7 7 6 0 TSC-22/dip/bun family CCDC92 PF14916.6 KXH39110.1 - 0.27 11.0 0.0 0.27 11.0 0.0 4.3 5 0 0 5 5 5 0 Coiled-coil domain of unknown function LPP PF04728.13 KXH39110.1 - 0.39 11.1 19.5 0.65 10.4 1.0 5.7 5 2 0 5 5 5 0 Lipoprotein leucine-zipper DivIC PF04977.15 KXH39110.1 - 1.8 8.4 59.0 0.068 12.9 2.0 7.7 7 1 1 8 8 8 0 Septum formation initiator Shugoshin_N PF07558.11 KXH39110.1 - 2.3 8.2 18.2 0.72 9.8 1.3 5.5 5 0 0 5 5 5 0 Shugoshin N-terminal coiled-coil region MCC-bdg_PDZ PF10506.9 KXH39110.1 - 2.8 8.0 14.2 25 5.0 0.1 4.9 4 0 0 4 4 4 0 PDZ domain of MCC-2 bdg protein for Usher syndrome TolA_bind_tri PF16331.5 KXH39110.1 - 4.3 7.5 36.7 5.2 7.2 2.8 6.4 5 1 1 6 6 6 0 TolA binding protein trimerisation Ank_3 PF13606.6 KXH39113.1 - 3.5e-24 82.2 7.3 0.049 14.2 0.0 10.3 11 0 0 11 11 11 7 Ankyrin repeat Ank_2 PF12796.7 KXH39113.1 - 1.8e-22 79.7 0.3 0.00032 21.2 0.0 6.4 4 3 2 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXH39113.1 - 3.9e-13 49.6 8.8 0.73 10.5 0.0 8.4 8 1 1 9 9 9 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXH39113.1 - 7.2e-12 45.3 6.3 0.062 13.6 0.0 7.5 7 0 0 7 7 7 3 Ankyrin repeats (many copies) Ank PF00023.30 KXH39113.1 - 4e-08 33.3 2.0 17 6.0 0.0 7.8 7 1 0 7 7 7 2 Ankyrin repeat MIT PF04212.18 KXH39113.1 - 0.14 12.2 0.0 11 6.1 0.0 2.8 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain MAJIN PF15077.6 KXH39114.1 - 0.59 9.9 4.6 0.45 10.3 3.2 1.5 1 1 0 1 1 1 0 Membrane-anchored junction protein bZIP_1 PF00170.21 KXH39115.1 - 0.061 13.4 4.7 0.15 12.2 4.7 1.6 1 0 0 1 1 1 0 bZIP transcription factor DUF4250 PF14056.6 KXH39115.1 - 0.12 12.4 0.3 0.29 11.1 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4250) p450 PF00067.22 KXH39116.1 - 4.9e-37 127.8 0.0 5.9e-37 127.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ApbA_C PF08546.11 KXH39116.1 - 0.027 14.7 0.0 0.055 13.7 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA C terminal Aminotran_1_2 PF00155.21 KXH39117.1 - 9.1e-50 169.8 0.0 1.1e-49 169.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_3 PF00202.21 KXH39117.1 - 0.1 11.2 0.0 0.16 10.6 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-III Arrestin_C PF02752.22 KXH39148.1 - 2.4e-15 57.2 0.7 2e-14 54.2 0.1 2.2 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain adh_short PF00106.25 KXH39149.1 - 2.5e-21 76.0 0.0 9.9e-17 61.0 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXH39149.1 - 8.1e-15 55.0 0.0 7.1e-14 51.9 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KXH39149.1 - 0.003 17.0 0.0 0.0042 16.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KXH39149.1 - 0.0033 17.4 0.0 0.0048 16.8 0.0 1.2 1 0 0 1 1 1 1 KR domain ORC6 PF05460.13 KXH39150.1 - 2.9e-34 118.9 0.0 4.8e-34 118.2 0.0 1.4 1 1 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) EF-hand_6 PF13405.6 KXH39151.1 - 5.2e-06 26.0 0.5 0.055 13.4 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 KXH39151.1 - 0.00056 19.3 0.1 0.0039 16.6 0.0 2.2 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.6 KXH39151.1 - 0.00083 18.7 0.1 0.0034 16.8 0.0 2.0 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 KXH39151.1 - 0.0011 19.4 1.0 0.0027 18.1 1.0 1.6 1 0 0 1 1 1 1 EF-hand domain pair Met_10 PF02475.16 KXH39152.1 - 6.7e-06 26.0 0.0 9.2e-05 22.3 0.0 2.1 2 0 0 2 2 2 1 Met-10+ like-protein Methyltransf_25 PF13649.6 KXH39152.1 - 0.082 13.6 0.0 0.2 12.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain AMH_N PF04709.12 KXH39152.1 - 0.11 11.4 0.0 0.21 10.5 0.0 1.3 1 0 0 1 1 1 0 Anti-Mullerian hormone, N terminal region Rpr2 PF04032.16 KXH39153.1 - 1e-14 54.6 0.9 1e-14 54.6 0.9 1.9 2 0 0 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain Nudix_N_2 PF14803.6 KXH39153.1 - 0.12 12.3 1.7 0.42 10.6 0.3 2.2 2 0 0 2 2 2 0 Nudix N-terminal zinc_ribbon_12 PF11331.8 KXH39153.1 - 0.36 10.7 6.1 1 9.2 0.2 2.8 3 0 0 3 3 3 0 Probable zinc-ribbon domain RNA_pol_Rpc4 PF05132.14 KXH39153.1 - 2.4 8.6 6.5 0.66 10.4 0.9 2.5 2 1 1 3 3 3 0 RNA polymerase III RPC4 zf-ZPR1 PF03367.13 KXH39154.1 - 1.4e-111 369.5 0.0 6.1e-56 188.7 0.0 2.3 2 0 0 2 2 2 2 ZPR1 zinc-finger domain NDT80_PhoG PF05224.12 KXH39157.1 - 2.8e-34 119.0 0.0 1.7e-33 116.4 0.0 2.0 2 0 0 2 2 2 1 NDT80 / PhoG like DNA-binding family Fungal_trans_2 PF11951.8 KXH39161.1 - 3.6e-47 161.0 0.6 4.9e-47 160.6 0.6 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF2786 PF10979.8 KXH39161.1 - 0.48 10.4 2.2 1.5 8.8 2.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2786) RPN5_C PF18098.1 KXH39161.1 - 0.66 10.1 2.4 0.95 9.6 0.2 2.4 3 0 0 3 3 3 0 26S proteasome regulatory subunit RPN5 C-terminal domain Pectate_lyase PF03211.13 KXH39163.1 - 1.3e-86 289.3 12.1 2e-86 288.7 12.1 1.2 1 0 0 1 1 1 1 Pectate lyase Fungal_trans PF04082.18 KXH39164.1 - 4.8e-14 52.0 0.0 7.2e-14 51.4 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH39164.1 - 4.4e-06 26.7 8.4 8.1e-06 25.9 8.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aminotran_3 PF00202.21 KXH39165.1 - 7.6e-98 327.8 0.0 9.1e-98 327.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 KXH39165.1 - 0.012 14.8 0.1 0.026 13.7 0.0 1.5 2 0 0 2 2 2 0 Aminotransferase class I and II MFS_1 PF07690.16 KXH39166.1 - 1.1e-24 87.1 58.6 2.1e-17 63.1 32.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Pec_lyase_C PF00544.19 KXH39167.1 - 6.9e-23 81.3 10.2 5.8e-22 78.3 10.2 2.0 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 KXH39167.1 - 4.8e-08 33.0 19.9 1.7e-05 24.7 9.9 2.2 1 1 1 2 2 2 2 Right handed beta helix region Acetyltransf_3 PF13302.7 KXH39168.1 - 3.7e-16 60.0 0.1 5.9e-16 59.4 0.0 1.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXH39168.1 - 1.1e-08 35.3 0.0 2.1e-08 34.4 0.0 1.5 1 1 1 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 KXH39168.1 - 0.00099 19.3 0.0 0.02 15.1 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain GRAS PF03514.14 KXH39168.1 - 0.13 11.2 0.3 0.2 10.6 0.3 1.2 1 0 0 1 1 1 0 GRAS domain family DUF3328 PF11807.8 KXH39169.1 - 4.1e-26 92.1 0.4 5.4e-26 91.7 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.8 KXH39170.1 - 2.5e-23 83.0 0.0 3.2e-23 82.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3105 PF11303.8 KXH39171.1 - 0.00062 19.9 0.1 15 5.7 0.0 3.0 1 1 2 3 3 3 3 Protein of unknown function (DUF3105) DUF3328 PF11807.8 KXH39172.1 - 5.1e-31 108.2 0.7 7.9e-31 107.5 0.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.8 KXH39173.1 - 4.9e-48 163.8 1.4 6.2e-48 163.5 1.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.8 KXH39174.1 - 5.8e-06 26.2 0.1 0.0031 17.3 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF3328) Pectinesterase PF01095.19 KXH39175.1 - 6.2e-49 166.3 9.8 8.3e-49 165.9 9.8 1.1 1 0 0 1 1 1 1 Pectinesterase Trypsin_2 PF13365.6 KXH39176.1 - 4.8e-09 37.3 1.3 7e-09 36.7 0.0 2.0 2 0 0 2 2 2 1 Trypsin-like peptidase domain Trypsin PF00089.26 KXH39176.1 - 1.1e-08 35.2 0.0 2.3e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 Trypsin Peptidase_C3 PF00548.20 KXH39176.1 - 0.0059 16.5 0.1 0.011 15.7 0.1 1.4 1 0 0 1 1 1 1 3C cysteine protease (picornain 3C) Ribosomal_S8e PF01201.22 KXH39176.1 - 0.068 13.4 0.4 0.12 12.5 0.4 1.4 1 0 0 1 1 1 0 Ribosomal protein S8e Metallophos PF00149.28 KXH39177.1 - 1.5e-14 55.0 0.0 3.5e-14 53.8 0.0 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KXH39177.1 - 6.2e-06 26.5 0.0 9.1e-05 22.7 0.0 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Ank_2 PF12796.7 KXH39178.1 - 9.4e-29 99.8 1.5 2.6e-10 40.8 0.0 4.6 3 1 0 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXH39178.1 - 7.4e-20 71.1 8.3 4e-07 30.4 0.1 6.5 3 1 5 8 8 8 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXH39178.1 - 2.6e-19 69.0 6.0 2.1e-06 27.9 0.0 6.2 5 1 1 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXH39178.1 - 2.8e-19 67.1 3.7 0.046 14.3 0.1 8.3 8 0 0 8 8 8 4 Ankyrin repeat Ank PF00023.30 KXH39178.1 - 3.8e-15 55.6 5.7 0.00033 21.0 0.1 7.2 8 0 0 8 8 8 3 Ankyrin repeat Helo_like_N PF17111.5 KXH39178.1 - 0.039 13.3 0.0 0.062 12.7 0.0 1.3 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins CFEM PF05730.11 KXH39179.1 - 5.2e-12 45.7 11.7 5.2e-12 45.7 11.7 1.7 2 0 0 2 2 2 1 CFEM domain Defensin_2 PF01097.18 KXH39179.1 - 0.00091 19.1 3.4 0.0029 17.5 3.4 1.9 1 0 0 1 1 1 1 Arthropod defensin Gamma-thionin PF00304.20 KXH39179.1 - 0.0023 18.1 2.3 0.0023 18.1 2.3 1.8 2 0 0 2 2 2 1 Gamma-thionin family FAD_binding_4 PF01565.23 KXH39180.1 - 1.7e-18 66.7 3.4 1.7e-18 66.7 3.4 2.2 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 KXH39180.1 - 1.1e-11 44.6 2.0 1.3e-11 44.3 0.4 1.9 2 0 0 2 2 2 1 Berberine and berberine like Cytokin-bind PF09265.10 KXH39180.1 - 0.11 11.8 0.5 0.25 10.7 0.4 1.5 1 1 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding HET PF06985.11 KXH39181.1 - 4.4e-33 114.7 2.3 5.2e-32 111.2 2.3 2.1 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MRP_L53 PF10780.9 KXH39181.1 - 0.0065 16.6 0.0 0.015 15.5 0.0 1.7 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 AA_permease PF00324.21 KXH39182.1 - 4.2e-125 418.1 36.9 5.1e-125 417.8 36.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KXH39182.1 - 6.3e-28 97.8 38.4 7.6e-28 97.5 38.4 1.0 1 0 0 1 1 1 1 Amino acid permease Cutinase PF01083.22 KXH39183.1 - 1e-45 155.9 0.7 1.3e-45 155.6 0.7 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 KXH39183.1 - 3.3e-06 26.8 0.4 8.4e-06 25.5 0.1 1.7 2 0 0 2 2 2 1 PE-PPE domain VirJ PF06057.11 KXH39183.1 - 0.0033 17.3 0.0 0.0053 16.7 0.0 1.3 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) DUF676 PF05057.14 KXH39183.1 - 0.0058 16.2 0.0 0.065 12.7 0.0 2.2 2 0 0 2 2 2 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 KXH39183.1 - 0.012 15.5 0.0 0.018 14.9 0.0 1.3 1 0 0 1 1 1 0 Palmitoyl protein thioesterase DUF2974 PF11187.8 KXH39183.1 - 0.017 14.7 0.0 0.025 14.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_2 PF02230.16 KXH39183.1 - 0.097 12.5 0.0 0.24 11.2 0.0 1.6 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Lipase_3 PF01764.25 KXH39183.1 - 0.15 11.9 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) FAD_binding_3 PF01494.19 KXH39184.1 - 2.6e-33 115.8 0.0 1.1e-32 113.6 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KXH39184.1 - 3.4e-09 36.8 0.1 0.00039 20.1 0.1 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KXH39184.1 - 5.6e-07 28.9 0.1 0.0019 17.3 0.0 2.5 3 0 0 3 3 3 2 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KXH39184.1 - 5.5e-06 25.8 0.4 0.0051 16.1 0.0 2.2 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXH39184.1 - 9.9e-06 25.7 0.1 2.3e-05 24.6 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KXH39184.1 - 0.00016 22.2 0.1 0.081 13.5 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KXH39184.1 - 0.00018 21.0 0.0 0.13 11.5 0.0 2.4 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase HI0933_like PF03486.14 KXH39184.1 - 0.00066 18.5 0.1 0.6 8.8 0.1 2.2 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.24 KXH39184.1 - 0.00093 18.4 0.1 0.0019 17.3 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 KXH39184.1 - 0.029 13.6 0.0 4.3 6.5 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Myosin_N PF02736.19 KXH39184.1 - 0.033 14.0 1.1 0.073 12.9 1.1 1.5 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain Trp_halogenase PF04820.14 KXH39184.1 - 0.08 11.8 0.1 10 4.8 0.0 2.5 3 0 0 3 3 3 0 Tryptophan halogenase Thi4 PF01946.17 KXH39184.1 - 0.18 11.0 0.1 0.29 10.3 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Aldedh PF00171.22 KXH39185.1 - 3e-150 500.8 0.0 3.7e-150 500.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family ADH_N PF08240.12 KXH39186.1 - 6.2e-24 84.0 1.1 1.1e-23 83.2 1.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXH39186.1 - 1.2e-20 73.8 0.0 1.9e-20 73.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KXH39186.1 - 9e-05 22.3 0.0 0.00031 20.6 0.0 1.8 2 0 0 2 2 2 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 KXH39186.1 - 0.001 20.1 0.0 0.0017 19.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase p450 PF00067.22 KXH39187.1 - 2.4e-46 158.4 0.0 4.8e-46 157.5 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 DUF3425 PF11905.8 KXH39188.1 - 9.5e-11 41.7 1.3 2.2e-10 40.6 1.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) Fer4_18 PF13746.6 KXH39188.1 - 0.1 12.8 1.5 0.14 12.4 0.3 1.7 2 0 0 2 2 2 0 4Fe-4S dicluster domain AAA_11 PF13086.6 KXH39188.1 - 0.39 10.4 8.1 2.4 7.9 1.8 2.2 2 0 0 2 2 2 0 AAA domain SUIM_assoc PF16619.5 KXH39188.1 - 3.8 7.7 16.3 0.075 13.1 8.4 2.3 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Baculo_PP31 PF05311.11 KXH39188.1 - 4.1 6.8 6.5 1.1 8.7 1.6 2.1 2 0 0 2 2 2 0 Baculovirus 33KDa late protein (PP31) ORC5_C PF14630.6 KXH39188.1 - 9.6 5.6 9.1 0.42 10.1 3.4 1.5 2 0 0 2 2 2 0 Origin recognition complex (ORC) subunit 5 C-terminus Atg14 PF10186.9 KXH39188.1 - 9.8 5.2 14.9 0.46 9.5 0.8 2.1 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 NTP_transf_9 PF04248.12 KXH39189.1 - 8.2e-39 131.4 0.6 5.3e-30 103.2 0.1 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF427) FAD_binding_4 PF01565.23 KXH39190.1 - 2.1e-22 79.3 3.3 4e-22 78.4 3.3 1.5 1 0 0 1 1 1 1 FAD binding domain MFS_1 PF07690.16 KXH39191.1 - 3.6e-11 42.6 27.1 2.3e-10 40.0 20.2 3.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Carn_acyltransf PF00755.20 KXH39192.1 - 6.5e-96 322.2 0.1 1.1e-95 321.5 0.1 1.3 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase ketoacyl-synt PF00109.26 KXH39192.1 - 8.7e-59 199.1 0.1 1e-57 195.6 0.0 2.6 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KXH39192.1 - 8.7e-54 182.1 0.0 1.9e-53 181.1 0.0 1.6 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.21 KXH39192.1 - 1.2e-52 179.4 0.0 2.8e-52 178.2 0.0 1.6 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 KXH39192.1 - 3.1e-51 174.4 0.0 5.6e-51 173.5 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 KXH39192.1 - 2.1e-31 108.4 0.3 1.2e-16 60.8 0.0 3.0 2 0 0 2 2 2 2 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KXH39192.1 - 7.9e-20 71.4 1.1 2.5e-11 44.0 0.0 3.0 2 0 0 2 2 2 2 Ketoacyl-synthetase C-terminal extension ADH_zinc_N_2 PF13602.6 KXH39192.1 - 6.2e-19 69.4 0.0 4.3e-17 63.4 0.0 2.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KXH39192.1 - 5.8e-14 52.2 0.0 6.2e-13 48.9 0.0 2.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase adh_short PF00106.25 KXH39192.1 - 3.8e-09 36.3 0.8 2.1e-08 33.9 0.0 2.5 3 0 0 3 3 3 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXH39192.1 - 1.3e-07 31.4 0.0 3.3e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase PP-binding PF00550.25 KXH39192.1 - 3.1e-07 30.6 0.2 8e-07 29.3 0.2 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_12 PF08242.12 KXH39192.1 - 6.1e-05 23.7 0.0 0.00025 21.7 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH39192.1 - 0.00052 20.7 0.0 0.0076 16.9 0.0 3.1 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH39192.1 - 0.002 17.9 0.0 0.029 14.2 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH39192.1 - 0.0042 17.7 0.0 0.018 15.7 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain NAD_binding_10 PF13460.6 KXH39192.1 - 0.0045 16.9 0.1 0.014 15.3 0.1 1.9 1 0 0 1 1 1 1 NAD(P)H-binding Collagen PF01391.18 KXH39192.1 - 0.082 12.7 2.8 0.17 11.6 2.8 1.4 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) RTA1 PF04479.13 KXH39193.1 - 4.8e-45 153.7 1.0 7.2e-45 153.1 1.0 1.2 1 0 0 1 1 1 1 RTA1 like protein DUF4131 PF13567.6 KXH39193.1 - 1.4 8.5 8.4 27 4.4 6.6 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) GFO_IDH_MocA PF01408.22 KXH39194.1 - 8.8e-17 62.0 0.0 1.8e-16 61.0 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA PF01408.22 KXH39195.1 - 3.3e-17 63.4 0.1 6.1e-17 62.5 0.1 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 KXH39195.1 - 0.089 13.4 0.1 0.15 12.7 0.1 1.3 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Fungal_trans PF04082.18 KXH39196.1 - 5.7e-06 25.6 0.1 8.9e-06 24.9 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH39196.1 - 0.022 14.9 4.2 0.049 13.8 4.2 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.25 KXH39198.1 - 1.4e-26 93.1 0.0 3.8e-25 88.5 0.0 2.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXH39198.1 - 6e-18 65.3 0.0 2.5e-16 60.0 0.0 2.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH39198.1 - 0.00045 20.2 0.5 0.071 13.0 0.6 2.7 2 1 0 2 2 2 2 KR domain Epimerase PF01370.21 KXH39198.1 - 0.043 13.3 0.1 0.41 10.1 0.0 2.3 3 0 0 3 3 3 0 NAD dependent epimerase/dehydratase family Zn_clus PF00172.18 KXH39199.1 - 0.47 10.6 3.9 0.79 9.9 3.9 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C6H2 PF15801.5 KXH39200.1 - 0.00021 21.5 8.6 0.017 15.4 0.6 2.8 3 0 0 3 3 3 2 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 KXH39200.1 - 0.003 17.6 2.2 0.003 17.6 2.2 3.3 3 0 0 3 3 3 1 MYND finger Spore_III_AF PF09581.10 KXH39200.1 - 0.51 10.3 0.0 0.51 10.3 0.0 2.2 3 0 0 3 3 3 0 Stage III sporulation protein AF (Spore_III_AF) SF3b10 PF07189.11 KXH39201.1 - 7.7e-37 125.3 0.0 8.6e-37 125.1 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) MAGE PF01454.19 KXH39202.1 - 6.1e-64 215.6 0.1 8.6e-64 215.1 0.1 1.2 1 0 0 1 1 1 1 MAGE family Replic_Relax PF13814.6 KXH39202.1 - 0.01 15.9 0.0 0.02 15.0 0.0 1.5 1 0 0 1 1 1 0 Replication-relaxation SLS PF14611.6 KXH39203.1 - 6.4e-30 104.6 6.4 1.1e-29 103.9 6.4 1.4 1 0 0 1 1 1 1 Mitochondrial inner-membrane-bound regulator GTP_EFTU PF00009.27 KXH39204.1 - 1.4e-52 178.1 0.1 2e-52 177.5 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KXH39204.1 - 2.6e-41 140.4 0.0 5.1e-41 139.5 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KXH39204.1 - 4.3e-15 55.9 2.2 6e-15 55.4 0.8 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KXH39204.1 - 0.0027 17.8 0.0 0.0071 16.4 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 KXH39204.1 - 0.065 13.2 0.3 0.23 11.4 0.3 1.9 1 0 0 1 1 1 0 Elongation factor Tu domain 4 ATE_C PF04377.15 KXH39220.1 - 1.4e-47 161.7 0.3 2.6e-47 160.8 0.3 1.5 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 KXH39220.1 - 1.7e-18 66.8 0.1 3.6e-18 65.7 0.1 1.5 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus Acetyltransf_6 PF13480.7 KXH39220.1 - 0.085 13.0 2.0 0.28 11.4 0.1 2.6 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain Snf7 PF03357.21 KXH39221.1 - 2.9e-37 127.9 9.0 3.4e-37 127.7 9.0 1.1 1 0 0 1 1 1 1 Snf7 DUF2293 PF10056.9 KXH39222.1 - 3.1e-33 113.9 0.3 3.1e-33 113.9 0.3 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2293) Mito_carr PF00153.27 KXH39223.1 - 1.2e-41 140.5 7.1 2.4e-15 56.2 0.1 4.1 3 1 0 3 3 3 3 Mitochondrial carrier protein Cation_efflux PF01545.21 KXH39223.1 - 0.015 15.0 0.0 2.6 7.7 0.0 2.5 3 0 0 3 3 3 0 Cation efflux family Complex1_LYR PF05347.15 KXH39224.1 - 0.00033 20.6 0.9 0.00061 19.8 0.4 1.7 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KXH39224.1 - 0.006 17.3 0.9 0.0085 16.8 0.9 1.5 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.6 KXH39224.1 - 0.055 14.1 0.6 0.11 13.2 0.6 1.7 1 1 0 1 1 1 0 Complex1_LYR-like Ribosomal_L3 PF00297.22 KXH39225.1 - 8e-17 61.3 3.1 3.3e-12 46.1 0.9 2.1 1 1 1 2 2 2 2 Ribosomal protein L3 Coa1 PF08695.10 KXH39226.1 - 1.4e-41 140.9 0.0 1.7e-41 140.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 Complex1_LYR PF05347.15 KXH39227.1 - 7.8e-10 38.7 1.8 1.2e-09 38.0 1.8 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Histone_H2A_C PF16211.5 KXH39228.1 - 2.2e-21 75.3 3.1 3.8e-21 74.5 3.1 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 KXH39228.1 - 6.8e-17 62.1 0.0 9.3e-17 61.6 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KXH39228.1 - 1e-05 25.7 0.0 1.4e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KXH39229.1 - 9.1e-22 77.8 2.0 1.1e-21 77.5 2.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KXH39229.1 - 2e-05 24.8 0.0 4.7e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 KXH39229.1 - 0.00033 21.1 0.0 0.00056 20.4 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A RP-C PF03428.13 KXH39229.1 - 0.045 13.4 0.1 0.11 12.1 0.1 1.6 1 1 0 1 1 1 0 Replication protein C N-terminal domain R3H PF01424.22 KXH39230.1 - 1.3e-15 57.1 0.0 2.9e-15 56.0 0.0 1.6 1 0 0 1 1 1 1 R3H domain G-patch PF01585.23 KXH39230.1 - 1e-10 41.3 1.0 3.6e-10 39.6 1.0 2.1 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KXH39230.1 - 0.0037 17.3 1.8 0.0063 16.6 0.3 2.3 2 0 0 2 2 2 1 G-patch domain Peptidase_C54 PF03416.19 KXH39231.1 - 5e-93 311.5 0.0 7.8e-93 310.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family C54 zf-C2H2 PF00096.26 KXH39232.1 - 0.00025 21.3 0.3 0.00042 20.6 0.3 1.3 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 KXH39232.1 - 0.00025 21.3 0.1 0.00036 20.8 0.1 1.2 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 KXH39232.1 - 0.00046 20.5 0.2 0.00074 19.8 0.2 1.3 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KXH39232.1 - 0.0088 16.8 0.1 0.015 16.1 0.1 1.4 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KXH39232.1 - 0.2 12.0 0.2 0.37 11.1 0.2 1.4 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding DUF678 PF05077.12 KXH39232.1 - 0.26 11.4 5.1 0.064 13.4 1.6 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF678) SPX PF03105.19 KXH39233.1 - 5.2e-65 220.8 0.3 6.8e-65 220.5 0.3 1.1 1 0 0 1 1 1 1 SPX domain zf-C3HC4 PF00097.25 KXH39233.1 - 8e-08 32.0 11.3 1.5e-07 31.2 11.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KXH39233.1 - 2.2e-07 30.9 9.4 4.1e-07 30.1 9.4 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 KXH39233.1 - 2.9e-07 30.2 9.9 5.6e-07 29.3 9.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KXH39233.1 - 4.1e-07 29.8 9.2 7.4e-07 28.9 9.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXH39233.1 - 6.9e-06 26.3 11.8 1.5e-05 25.2 11.8 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KXH39233.1 - 6.4e-05 22.8 10.2 0.00015 21.6 10.2 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KXH39233.1 - 7.9e-05 22.6 8.0 0.00019 21.4 8.0 1.7 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KXH39233.1 - 0.018 14.9 10.9 0.083 12.8 11.2 1.9 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 KXH39233.1 - 0.046 13.9 4.3 0.099 12.8 4.3 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_6 PF14835.6 KXH39233.1 - 0.046 13.6 2.9 0.11 12.3 2.9 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 KXH39233.1 - 0.087 13.1 10.0 0.24 11.7 10.0 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KXH39233.1 - 0.093 12.8 2.8 0.2 11.8 2.8 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger TerY_C PF15616.6 KXH39233.1 - 0.19 11.9 1.6 0.34 11.0 1.6 1.5 1 0 0 1 1 1 0 TerY-C metal binding domain zf-RING_4 PF14570.6 KXH39233.1 - 0.23 11.3 9.8 0.029 14.2 5.2 1.8 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Cys_Met_Meta_PP PF01053.20 KXH39234.1 - 7.7e-33 113.6 0.0 1e-32 113.1 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KXH39234.1 - 0.097 11.8 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II PT PF04886.12 KXH39235.1 - 1.8e-06 27.4 27.1 0.026 14.1 4.6 4.4 1 1 1 2 2 2 2 PT repeat Gly-zipper_Omp PF13488.6 KXH39235.1 - 0.00077 19.4 6.0 0.0015 18.5 6.0 1.4 1 0 0 1 1 1 1 Glycine zipper DUF1269 PF06897.12 KXH39235.1 - 0.31 11.3 0.8 0.58 10.5 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) EMG1 PF03587.14 KXH39236.1 - 8.5e-79 263.7 0.0 1e-78 263.5 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase Ribosomal_S17 PF00366.20 KXH39237.1 - 1.4e-21 76.3 2.6 1.4e-21 76.3 2.6 1.8 2 0 0 2 2 2 1 Ribosomal protein S17 AAA PF00004.29 KXH39238.1 - 1.9e-38 131.8 0.0 3.5e-38 131.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 KXH39238.1 - 1.3e-08 34.7 0.0 1.3e-07 31.5 0.0 2.5 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_lid_3 PF17862.1 KXH39238.1 - 4.9e-08 32.7 0.5 1.1e-07 31.5 0.1 1.9 2 0 0 2 2 1 1 AAA+ lid domain AAA_22 PF13401.6 KXH39238.1 - 1.7e-05 25.1 0.9 0.00044 20.5 0.2 3.0 3 1 0 3 3 2 1 AAA domain RuvB_N PF05496.12 KXH39238.1 - 5.4e-05 23.0 0.0 0.0001 22.1 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KXH39238.1 - 0.0003 21.2 0.5 0.0017 18.8 0.5 2.4 1 1 0 1 1 1 1 AAA ATPase domain TIP49 PF06068.13 KXH39238.1 - 0.00094 18.5 0.0 0.0017 17.6 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain DUF815 PF05673.13 KXH39238.1 - 0.0013 17.9 0.0 0.0023 17.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 KXH39238.1 - 0.003 17.5 0.0 0.0098 15.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 KXH39238.1 - 0.0033 17.5 0.0 0.038 14.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 KXH39238.1 - 0.0033 16.8 0.1 0.01 15.2 0.1 1.8 2 0 0 2 2 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 KXH39238.1 - 0.0043 16.8 0.0 0.0078 16.0 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_2 PF07724.14 KXH39238.1 - 0.0067 16.6 0.0 0.013 15.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 KXH39238.1 - 0.026 14.7 0.0 0.06 13.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KXH39238.1 - 0.041 14.4 0.0 0.12 12.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KXH39238.1 - 0.046 14.0 0.0 0.097 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KXH39238.1 - 0.053 13.2 0.2 0.15 11.8 0.0 1.9 3 0 0 3 3 1 0 AAA domain AAA_25 PF13481.6 KXH39238.1 - 0.064 12.8 0.0 0.18 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KXH39238.1 - 0.077 13.2 0.2 0.77 10.0 0.1 2.4 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KXH39238.1 - 0.11 12.5 0.0 0.33 10.9 0.0 1.9 2 0 0 2 2 1 0 NACHT domain AAA_7 PF12775.7 KXH39238.1 - 0.16 11.4 0.0 0.36 10.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region PhoH PF02562.16 KXH39238.1 - 0.19 11.1 0.0 0.52 9.7 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_11 PF13086.6 KXH39238.1 - 1.1 9.0 0.0 1.1 9.0 0.0 2.7 2 2 0 2 2 1 0 AAA domain COG6 PF06419.11 KXH39239.1 - 7.2e-216 718.2 5.2 8.2e-216 718.0 5.2 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 COG2 PF06148.11 KXH39239.1 - 0.026 14.6 0.3 0.026 14.6 0.3 2.6 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF948 PF06103.11 KXH39239.1 - 0.075 13.3 0.4 1.7 8.9 0.1 3.0 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) RmuC PF02646.16 KXH39239.1 - 0.24 10.5 3.3 0.2 10.8 0.1 2.3 2 0 0 2 2 2 0 RmuC family Muted PF14942.6 KXH39239.1 - 1.6 9.0 5.1 6.2 7.1 0.5 3.0 2 1 0 2 2 2 0 Organelle biogenesis, Muted-like protein DASH_Dad3 PF08656.10 KXH39239.1 - 3 8.0 5.4 1.4 9.0 0.0 3.1 4 0 0 4 4 4 0 DASH complex subunit Dad3 APG9 PF04109.16 KXH39240.1 - 2.9e-194 646.6 17.2 3.3e-194 646.4 17.2 1.0 1 0 0 1 1 1 1 Autophagy protein Apg9 Mito_carr PF00153.27 KXH39241.1 - 2.1e-68 226.3 4.1 1e-22 79.9 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KXH39241.1 - 0.011 15.0 5.7 0.71 9.0 0.4 3.2 1 1 2 3 3 3 0 Gammaproteobacterial serine protease Bac_export_2 PF01312.19 KXH39241.1 - 0.037 13.2 0.0 0.056 12.7 0.0 1.2 1 0 0 1 1 1 0 FlhB HrpN YscU SpaS Family DnaJ PF00226.31 KXH39242.1 - 5.1e-21 74.6 1.9 5.1e-21 74.6 1.9 2.5 3 0 0 3 3 3 1 DnaJ domain TPR_2 PF07719.17 KXH39242.1 - 1.7e-17 62.0 2.7 0.0086 16.1 0.0 8.1 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_1 PF00515.28 KXH39242.1 - 1.9e-15 55.9 0.4 0.0002 21.0 0.0 6.3 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 KXH39242.1 - 2.5e-13 49.6 5.4 0.026 15.3 0.1 6.9 4 2 4 8 8 7 3 Tetratricopeptide repeat TPR_8 PF13181.6 KXH39242.1 - 1.2e-12 47.0 0.8 0.0018 18.3 0.0 6.8 8 0 0 8 8 6 3 Tetratricopeptide repeat TPR_9 PF13371.6 KXH39242.1 - 4e-12 46.1 0.2 0.00061 19.9 0.0 4.5 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 KXH39242.1 - 1.5e-09 37.4 0.6 0.027 14.2 0.1 4.8 4 1 1 5 5 4 3 TPR repeat TPR_19 PF14559.6 KXH39242.1 - 4.5e-09 36.7 4.9 0.021 15.3 0.0 4.8 3 1 2 5 5 4 3 Tetratricopeptide repeat TPR_6 PF13174.6 KXH39242.1 - 2e-07 31.2 7.3 3.3 8.5 0.0 7.3 8 0 0 8 8 7 3 Tetratricopeptide repeat PknG_TPR PF16918.5 KXH39242.1 - 5.6e-07 28.6 0.5 0.0002 20.2 0.2 2.9 2 1 0 3 3 3 1 Protein kinase G tetratricopeptide repeat TPR_17 PF13431.6 KXH39242.1 - 1.1e-06 28.6 0.3 0.0008 19.6 0.1 4.9 6 0 0 6 6 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 KXH39242.1 - 4.3e-05 23.2 4.5 1 9.6 0.0 6.0 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_15 PF13429.6 KXH39242.1 - 6.3e-05 22.3 3.7 3.9 6.6 0.0 5.2 2 2 3 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 KXH39242.1 - 0.0007 20.2 6.7 0.17 12.6 0.1 4.8 3 1 2 5 5 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KXH39242.1 - 0.0016 18.6 10.7 0.014 15.6 0.1 4.9 4 1 1 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 KXH39242.1 - 0.0091 16.3 11.8 1.1 9.6 0.0 5.7 2 2 3 6 6 5 1 Tetratricopeptide repeat TPR_20 PF14561.6 KXH39242.1 - 0.31 11.4 4.9 2.2 8.7 0.0 4.1 2 2 3 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 KXH39242.1 - 4.8 7.2 7.6 1.3e+02 2.6 0.0 5.3 6 0 0 6 6 5 0 Tetratricopeptide repeat KCNQ_channel PF03520.14 KXH39243.1 - 0.011 15.6 0.2 5.2 6.9 0.0 2.2 1 1 1 2 2 2 0 KCNQ voltage-gated potassium channel DUF4051 PF13260.6 KXH39243.1 - 0.079 12.7 0.2 0.18 11.6 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4051) FUSC PF04632.12 KXH39243.1 - 3.4 6.1 17.8 1.5 7.3 9.3 2.8 1 1 1 2 2 2 0 Fusaric acid resistance protein family PspB PF06667.12 KXH39243.1 - 4.1 7.5 5.4 2.3 8.3 0.2 3.0 2 1 1 3 3 3 0 Phage shock protein B DivIVA PF05103.13 KXH39243.1 - 6.8 6.8 7.3 0.66 10.1 0.2 2.7 2 1 0 3 3 3 0 DivIVA protein Vac14_Fig4_bd PF11916.8 KXH39244.1 - 4e-62 209.1 10.9 1.2e-48 165.1 7.2 2.6 1 1 1 2 2 2 2 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 KXH39244.1 - 6.6e-45 151.7 0.0 3.3e-42 143.0 0.0 3.7 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 KXH39244.1 - 2.6e-08 34.2 7.4 0.00012 22.5 0.1 5.4 6 0 0 6 6 6 2 HEAT-like repeat Cnd1 PF12717.7 KXH39244.1 - 2.9e-08 33.9 0.1 0.0072 16.4 0.1 3.5 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KXH39244.1 - 2.9e-07 30.2 1.6 0.00062 19.8 0.0 5.4 4 0 0 4 4 4 1 HEAT repeat HEAT_2 PF13646.6 KXH39244.1 - 0.00095 19.5 1.7 0.27 11.6 0.0 4.5 4 1 0 4 4 4 1 HEAT repeats Arm PF00514.23 KXH39244.1 - 0.0037 17.2 0.0 0.71 10.0 0.0 3.9 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat SUZ PF12752.7 KXH39245.1 - 1.8 9.4 6.8 0.93 10.3 1.0 2.3 2 0 0 2 2 2 0 SUZ domain FA_desaturase PF00487.24 KXH39246.1 - 8.5e-25 88.0 27.4 1.4e-24 87.3 27.4 1.4 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 KXH39246.1 - 9.2e-10 38.5 0.1 3.9e-09 36.5 0.0 2.0 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glyco_hydro_17 PF00332.18 KXH39247.1 - 4.4e-06 26.5 2.2 6.4e-06 26.0 0.2 2.1 2 1 1 3 3 3 1 Glycosyl hydrolases family 17 Aminotran_1_2 PF00155.21 KXH39248.1 - 1.3e-36 126.6 0.0 1.5e-36 126.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KXH39248.1 - 4.6e-05 22.1 0.0 8.1e-05 21.3 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme OKR_DC_1 PF01276.20 KXH39248.1 - 0.069 11.9 0.0 0.49 9.1 0.0 2.3 2 1 0 2 2 2 0 Orn/Lys/Arg decarboxylase, major domain SnAPC_2_like PF11035.8 KXH39248.1 - 0.079 13.1 0.1 0.12 12.5 0.1 1.2 1 0 0 1 1 1 0 Small nuclear RNA activating complex subunit 2, SNAP190 Myb Glucan_synthase PF02364.15 KXH39249.1 - 0 1373.2 0.0 0 1372.2 0.0 1.5 2 0 0 2 2 2 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 KXH39249.1 - 1.1e-43 148.7 0.8 3.6e-43 147.0 0.8 2.0 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 SprT-like PF10263.9 KXH39250.1 - 1.2e-37 128.2 1.6 1.2e-37 128.2 1.6 1.8 2 0 0 2 2 2 1 SprT-like family Zn_ribbon_SprT PF17283.2 KXH39250.1 - 2.4e-09 37.0 3.4 4.2e-09 36.2 3.4 1.4 1 0 0 1 1 1 1 SprT-like zinc ribbon domain HMG_box PF00505.19 KXH39250.1 - 5.8e-05 23.4 2.0 9.6e-05 22.7 0.1 2.3 2 0 0 2 2 2 1 HMG (high mobility group) box YABBY PF04690.13 KXH39250.1 - 0.009 16.6 0.6 0.009 16.6 0.6 2.6 3 0 0 3 3 3 1 YABBY protein CPL PF08144.11 KXH39250.1 - 0.029 14.7 0.6 0.078 13.3 0.6 1.7 1 0 0 1 1 1 0 CPL (NUC119) domain STOP PF05217.12 KXH39250.1 - 0.065 13.6 0.1 0.21 11.9 0.1 1.9 1 0 0 1 1 1 0 STOP protein Zn-ribbon_8 PF09723.10 KXH39250.1 - 0.087 13.0 1.8 0.21 11.7 1.8 1.6 1 0 0 1 1 1 0 Zinc ribbon domain DUF4379 PF14311.6 KXH39250.1 - 1.2 9.5 7.0 0.9 10.0 3.9 2.5 2 0 0 2 2 2 0 Probable Zinc-ribbon domain Mog1 PF04603.12 KXH39252.1 - 2.6e-38 131.5 0.0 3.1e-38 131.2 0.0 1.1 1 0 0 1 1 1 1 Ran-interacting Mog1 protein HIT PF01230.23 KXH39253.1 - 2.2e-23 82.8 0.1 3.1e-23 82.4 0.1 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 KXH39253.1 - 1.5e-13 51.3 0.0 2.2e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 KXH39253.1 - 3.8e-05 23.5 0.3 6.1e-05 22.9 0.3 1.4 1 1 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 LppA PF16708.5 KXH39253.1 - 0.13 12.2 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 Lipoprotein confined to pathogenic Mycobacterium CRAL_TRIO PF00650.20 KXH39254.1 - 1.8e-41 141.5 0.0 3e-41 140.8 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KXH39254.1 - 8e-15 54.8 1.6 1.4e-14 54.0 0.2 2.1 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KXH39254.1 - 1.4e-07 31.8 0.0 2.3e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DNA_pol_A_exoN PF18305.1 KXH39254.1 - 0.1 12.9 0.1 0.28 11.5 0.1 1.8 1 0 0 1 1 1 0 3' to 5' exonuclease C-terminal domain DASH_Dam1 PF08653.10 KXH39255.1 - 2.5e-26 91.2 2.7 3.7e-26 90.7 2.7 1.3 1 0 0 1 1 1 1 DASH complex subunit Dam1 zf-C2H2_jaz PF12171.8 KXH39256.1 - 1.3e-10 41.2 0.3 2.1e-10 40.6 0.3 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KXH39256.1 - 0.031 14.3 0.3 0.053 13.5 0.3 1.4 1 0 0 1 1 1 0 C2H2-type zinc finger GH-E PF14410.6 KXH39256.1 - 0.069 13.6 0.1 0.15 12.5 0.1 1.6 1 0 0 1 1 1 0 HNH/ENDO VII superfamily nuclease with conserved GHE residues zf-C2H2_2 PF12756.7 KXH39256.1 - 0.094 13.1 0.3 0.2 12.0 0.2 1.5 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 KXH39256.1 - 0.11 13.4 0.1 0.26 12.2 0.1 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger Gaa1 PF04114.14 KXH39257.1 - 3.8e-172 573.8 1.5 4.4e-172 573.6 1.5 1.0 1 0 0 1 1 1 1 Gaa1-like, GPI transamidase component PCI PF01399.27 KXH39258.1 - 1.2e-10 41.9 0.0 2.1e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 PCI domain Rpn9_C PF18261.1 KXH39258.1 - 1.6e-08 33.9 1.8 3.6e-08 32.9 1.8 1.6 1 0 0 1 1 1 1 Rpn9 C-terminal helix Dam PF05869.11 KXH39258.1 - 0.052 13.1 0.0 0.13 11.9 0.0 1.7 2 0 0 2 2 2 0 DNA N-6-adenine-methyltransferase (Dam) N6-adenineMlase PF10237.9 KXH39259.1 - 1.8e-51 174.1 0.1 5.3e-51 172.6 0.0 1.8 2 0 0 2 2 2 1 Probable N6-adenine methyltransferase NmrA PF05368.13 KXH39259.1 - 1.1e-16 61.1 0.0 1.8e-16 60.4 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXH39259.1 - 4.6e-14 52.7 0.0 1.1e-13 51.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KXH39259.1 - 1.1e-13 51.2 0.1 2.3e-13 50.2 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXH39259.1 - 4e-10 39.2 0.1 1.4e-09 37.4 0.1 1.8 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KXH39259.1 - 2.5e-08 33.3 0.7 8.5e-07 28.4 0.0 2.8 2 1 0 2 2 2 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 KXH39259.1 - 2.1e-07 30.7 0.1 3.8e-07 29.8 0.1 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 KXH39259.1 - 0.0012 18.4 0.0 0.0019 17.7 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.12 KXH39259.1 - 0.0073 15.5 0.4 1.7 7.8 0.3 2.8 1 1 1 2 2 2 1 Male sterility protein 2-Hacid_dh_C PF02826.19 KXH39259.1 - 0.019 14.4 0.1 4.4 6.6 0.2 3.0 2 1 1 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain KR PF08659.10 KXH39259.1 - 0.057 13.3 0.0 12 5.8 0.0 2.3 2 0 0 2 2 2 0 KR domain Polysacc_synt_2 PF02719.15 KXH39259.1 - 0.088 11.9 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein PCIF1_WW PF12237.8 KXH39259.1 - 0.11 12.1 0.2 1.1 8.9 0.1 2.5 3 0 0 3 3 3 0 Phosphorylated CTD interacting factor 1 WW domain adh_short_C2 PF13561.6 KXH39259.1 - 0.15 11.6 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase UCH PF00443.29 KXH39260.1 - 9.1e-49 166.3 1.2 9.1e-49 166.3 1.2 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KXH39260.1 - 2.2e-29 103.1 4.1 4.7e-29 102.0 4.1 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KXH39260.1 - 2.8e-05 24.4 0.3 2.8e-05 24.4 0.3 2.4 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein zf-CCHC PF00098.23 KXH39260.1 - 5.2 7.3 10.6 31 4.9 0.0 4.5 4 0 0 4 4 4 0 Zinc knuckle DZR PF12773.7 KXH39260.1 - 6.3 6.9 12.0 19 5.4 4.4 3.8 4 1 0 4 4 4 0 Double zinc ribbon BLACT_WH PF17778.1 KXH39261.1 - 1.6e-18 66.4 0.1 2.9e-18 65.6 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase associated winged helix domain Lactamase_B PF00753.27 KXH39261.1 - 9.6e-17 61.6 1.0 1.3e-11 44.9 0.2 2.2 1 1 1 2 2 2 2 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KXH39261.1 - 1.4e-06 28.0 0.1 2.8e-06 27.0 0.1 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KXH39261.1 - 0.00029 20.8 0.1 0.00044 20.2 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Ytp1 PF10355.9 KXH39262.1 - 7.9e-121 402.5 6.9 1.2e-120 401.9 6.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 KXH39262.1 - 4.7e-32 109.9 5.6 4.7e-32 109.9 5.6 3.4 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) ZYG-11_interact PF05884.12 KXH39262.1 - 0.091 12.2 1.6 0.2 11.1 1.6 1.5 1 0 0 1 1 1 0 Interactor of ZYG-11 DUF5504 PF17608.2 KXH39262.1 - 0.34 11.0 7.4 0.19 11.8 2.5 2.7 3 0 0 3 3 3 0 Family of unknown function (DUF5504) TadE PF07811.12 KXH39262.1 - 7.1 7.0 13.4 1.3 9.4 0.5 4.6 4 0 0 4 4 4 0 TadE-like protein Rsa3 PF14615.6 KXH39263.1 - 3.4e-21 74.6 0.2 4.5e-21 74.2 0.2 1.2 1 0 0 1 1 1 1 Ribosome-assembly protein 3 CFEM PF05730.11 KXH39264.1 - 2.3e-15 56.4 10.6 2.7e-15 56.2 10.6 1.1 1 0 0 1 1 1 1 CFEM domain CBS PF00571.28 KXH39265.1 - 2.4e-08 34.3 0.5 0.02 15.3 0.1 3.2 3 0 0 3 3 3 3 CBS domain Sec23_trunk PF04811.15 KXH39267.1 - 2.1e-50 171.6 0.0 5.5e-50 170.2 0.0 1.7 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 KXH39267.1 - 1.4e-24 85.9 0.1 2.4e-24 85.1 0.1 1.4 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 KXH39267.1 - 2.4e-17 63.5 0.0 4.4e-17 62.6 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 KXH39267.1 - 1.4e-14 53.9 4.9 2.9e-14 52.8 4.9 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 KXH39267.1 - 1.6e-05 24.7 0.0 4.3e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat DEK_C PF08766.11 KXH39267.1 - 0.054 13.4 0.1 0.098 12.6 0.1 1.4 1 0 0 1 1 1 0 DEK C terminal domain Lactamase_B_6 PF16661.5 KXH39268.1 - 8.9e-66 221.0 0.0 1.3e-65 220.4 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain CPSF100_C PF13299.6 KXH39268.1 - 3.4e-54 183.6 2.2 3.4e-54 183.6 2.2 2.3 3 0 0 3 3 3 1 Cleavage and polyadenylation factor 2 C-terminal RMMBL PF07521.12 KXH39268.1 - 1.4e-16 60.1 0.0 4.1e-16 58.7 0.0 1.9 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Beta-Casp PF10996.8 KXH39268.1 - 2.9e-16 59.7 0.1 3.3e-15 56.3 0.0 2.7 2 1 0 3 3 3 1 Beta-Casp domain Lactamase_B_2 PF12706.7 KXH39268.1 - 0.025 14.1 0.0 0.086 12.3 0.0 1.8 1 1 0 2 2 2 0 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KXH39268.1 - 0.13 12.2 0.0 0.37 10.8 0.0 1.7 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily Zn_clus PF00172.18 KXH39269.1 - 3.7e-05 23.7 9.1 3.7e-05 23.7 9.1 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acetyltransf_2 PF00797.17 KXH39270.1 - 3e-41 141.8 0.0 3.8e-41 141.5 0.0 1.1 1 0 0 1 1 1 1 N-acetyltransferase DUF3830 PF12903.7 KXH39270.1 - 0.13 11.9 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3830) DUF5505 PF17610.2 KXH39270.1 - 0.13 12.2 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5505) Inhibitor_I9 PF05922.16 KXH39271.1 - 0.0072 17.0 0.0 0.012 16.2 0.0 1.3 1 1 0 1 1 1 1 Peptidase inhibitor I9 OSCP PF00213.18 KXH39271.1 - 0.062 13.4 0.0 0.079 13.1 0.0 1.1 1 0 0 1 1 1 0 ATP synthase delta (OSCP) subunit TIM PF00121.18 KXH39272.1 - 6.1e-54 183.0 0.0 6.9e-54 182.8 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase LacAB_rpiB PF02502.18 KXH39273.1 - 5.1e-43 146.4 0.3 5.8e-43 146.2 0.3 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase Dak1 PF02733.17 KXH39274.1 - 4.6e-97 324.6 0.0 6.2e-97 324.2 0.0 1.1 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 KXH39274.1 - 2.6e-42 144.7 0.3 4.2e-42 144.0 0.3 1.3 1 0 0 1 1 1 1 DAK2 domain Ank_2 PF12796.7 KXH39277.1 - 2e-77 255.9 10.2 3e-15 56.6 0.0 7.0 2 2 5 7 7 7 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXH39277.1 - 1.9e-58 194.1 8.1 3.2e-10 40.3 0.0 8.6 4 2 5 9 9 9 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXH39277.1 - 4e-52 168.1 1.5 0.0012 19.2 0.0 12.9 12 0 0 12 12 12 11 Ankyrin repeat Ank PF00023.30 KXH39277.1 - 2.5e-51 170.0 12.2 0.00013 22.2 0.0 12.7 12 0 0 12 12 12 10 Ankyrin repeat Ank_5 PF13857.6 KXH39277.1 - 6.8e-46 153.7 11.3 4.8e-08 33.1 0.2 10.3 2 2 9 11 11 11 10 Ankyrin repeats (many copies) HeLo PF14479.6 KXH39277.1 - 3.7e-13 49.8 0.1 2.3e-12 47.2 0.1 2.1 1 1 0 1 1 1 1 Prion-inhibition and propagation NACHT PF05729.12 KXH39277.1 - 5.1e-10 39.5 0.0 1.3e-09 38.1 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KXH39277.1 - 0.00036 20.9 0.0 0.0013 19.1 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KXH39277.1 - 0.01 16.1 0.0 0.026 14.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain C1_2 PF03107.16 KXH39277.1 - 0.021 15.1 4.5 0.046 14.1 4.5 1.5 1 0 0 1 1 1 0 C1 domain NB-ARC PF00931.22 KXH39277.1 - 0.14 11.3 0.0 0.26 10.5 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Abhydrolase_6 PF12697.7 KXH39278.1 - 6.1e-17 63.0 0.0 9.4e-17 62.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXH39278.1 - 1.4e-16 60.9 0.0 3.3e-16 59.7 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXH39278.1 - 9.4e-10 38.2 0.0 1.6e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF915 PF06028.11 KXH39278.1 - 1.7e-05 24.3 0.0 0.029 13.7 0.0 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase of unknown function (DUF915) Esterase PF00756.20 KXH39278.1 - 0.0086 15.7 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Palm_thioest PF02089.15 KXH39278.1 - 0.0098 15.8 0.0 0.012 15.4 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Chlorophyllase PF07224.11 KXH39278.1 - 0.032 13.3 0.1 0.074 12.0 0.1 1.5 1 1 0 1 1 1 0 Chlorophyllase Thioesterase PF00975.20 KXH39278.1 - 0.046 13.8 0.0 0.081 13.0 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain Lipase_3 PF01764.25 KXH39278.1 - 0.098 12.5 0.1 0.16 11.8 0.1 1.3 1 0 0 1 1 1 0 Lipase (class 3) CFEM PF05730.11 KXH39279.1 - 2.5e-11 43.5 12.1 4.9e-11 42.6 12.1 1.5 1 0 0 1 1 1 1 CFEM domain NAD_binding_4 PF07993.12 KXH39280.1 - 1.7e-37 129.0 0.0 3.3e-37 128.0 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 KXH39280.1 - 7.6e-31 107.1 0.0 1.2e-30 106.5 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 KXH39280.1 - 1.1e-10 41.4 0.0 2.1e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KXH39280.1 - 9.5e-05 22.7 0.0 0.0003 21.1 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site GDP_Man_Dehyd PF16363.5 KXH39280.1 - 0.0054 16.2 0.0 0.024 14.0 0.0 1.9 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase KR PF08659.10 KXH39280.1 - 0.024 14.6 0.0 0.1 12.5 0.0 2.1 2 0 0 2 2 2 0 KR domain MFS_1 PF07690.16 KXH39282.1 - 3.2e-35 121.7 20.6 3.2e-35 121.7 20.6 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily SfLAP PF11139.8 KXH39282.1 - 0.029 13.8 14.5 0.074 12.5 1.8 3.3 3 0 0 3 3 3 0 Sap, sulfolipid-1-addressing protein DUF1772 PF08592.11 KXH39282.1 - 3.2 8.1 15.7 0.16 12.3 0.6 3.4 2 2 1 3 3 3 0 Domain of unknown function (DUF1772) Cu-oxidase_2 PF07731.14 KXH39283.1 - 5e-26 91.1 3.5 3.5e-24 85.1 1.7 2.5 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 KXH39283.1 - 1.5e-18 66.9 0.0 4.1e-18 65.5 0.0 1.8 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase PF00394.22 KXH39283.1 - 1.7e-05 25.0 0.0 0.0013 18.9 0.0 2.7 3 0 0 3 3 3 1 Multicopper oxidase DUF2555 PF10742.9 KXH39283.1 - 0.07 12.9 0.1 0.16 11.8 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2555) Glyco_hydro_11 PF00457.17 KXH39285.1 - 2.2e-82 275.0 23.9 2.6e-82 274.8 23.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 MMU163 PF17119.5 KXH39286.1 - 3 6.9 4.4 4.4 6.4 4.4 1.3 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis NPR3 PF03666.13 KXH39286.1 - 4 6.1 6.6 5.1 5.8 6.6 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Presenilin PF01080.17 KXH39286.1 - 7.4 5.2 8.1 8.7 5.0 8.1 1.1 1 0 0 1 1 1 0 Presenilin Macoilin PF09726.9 KXH39286.1 - 7.4 5.0 10.1 7.9 4.9 10.1 1.1 1 0 0 1 1 1 0 Macoilin family Pol_alpha_B_N PF08418.10 KXH39286.1 - 8.6 6.2 10.9 10 6.0 10.9 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Aminotran_1_2 PF00155.21 KXH39288.1 - 1.3e-15 57.5 0.0 1.6e-15 57.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 KXH39288.1 - 0.0001 21.2 0.0 0.0003 19.7 0.0 1.6 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase DegT_DnrJ_EryC1 PF01041.17 KXH39288.1 - 0.017 14.4 0.1 0.044 13.1 0.0 1.6 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Fungal_trans PF04082.18 KXH39289.1 - 4.8e-05 22.5 0.1 7.7e-05 21.8 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain NAD_binding_10 PF13460.6 KXH39290.1 - 2.6e-10 40.5 0.1 4.5e-10 39.7 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KXH39290.1 - 9e-09 35.7 0.1 1.9e-08 34.7 0.1 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NmrA PF05368.13 KXH39290.1 - 1.7e-06 27.8 0.2 3.3e-06 26.8 0.2 1.5 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.12 KXH39290.1 - 1e-05 24.9 0.2 0.0013 17.9 0.1 2.4 3 0 0 3 3 3 1 Male sterility protein TrkA_N PF02254.18 KXH39290.1 - 4e-05 23.8 0.1 7.7e-05 22.9 0.1 1.4 1 0 0 1 1 1 1 TrkA-N domain 3Beta_HSD PF01073.19 KXH39290.1 - 5.1e-05 22.4 0.0 0.0038 16.3 0.1 2.2 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KXH39290.1 - 0.00012 21.7 0.2 0.037 13.5 0.1 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.17 KXH39290.1 - 0.0024 18.4 0.0 0.0052 17.3 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 KXH39290.1 - 0.0089 16.1 0.0 0.016 15.3 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase GDP_Man_Dehyd PF16363.5 KXH39290.1 - 0.012 15.0 0.0 1 8.7 0.0 2.2 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Semialdhyde_dh PF01118.24 KXH39290.1 - 0.022 15.2 0.0 0.044 14.2 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_3 PF03447.16 KXH39290.1 - 0.15 12.7 0.1 0.31 11.7 0.1 1.6 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 KXH39290.1 - 0.19 10.8 0.0 0.3 10.2 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein MFS_1 PF07690.16 KXH39291.1 - 2.3e-23 82.7 26.0 2.9e-23 82.4 26.0 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Trp_oprn_chp PF09534.10 KXH39291.1 - 0.14 11.9 0.4 1.2 8.9 0.0 2.2 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) CoA_transf_3 PF02515.17 KXH39292.1 - 4.1e-109 365.1 0.0 4.6e-109 364.9 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III 2-Hacid_dh_C PF02826.19 KXH39292.1 - 0.13 11.6 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain RisS_PPD PF16524.5 KXH39292.1 - 0.17 12.1 0.1 0.36 11.1 0.1 1.4 1 0 0 1 1 1 0 Periplasmic domain of Sensor histidine kinase RisS Acyl-CoA_dh_1 PF00441.24 KXH39293.1 - 2.9e-31 108.7 2.4 5e-31 107.9 2.4 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KXH39293.1 - 2.3e-20 73.3 0.1 5.2e-20 72.2 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KXH39293.1 - 5.6e-20 71.4 0.0 1.1e-19 70.4 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KXH39293.1 - 6.5e-16 58.8 5.2 1.4e-15 57.8 3.3 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Fungal_trans PF04082.18 KXH39294.1 - 2.2e-30 105.6 0.0 3.2e-30 105.1 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH39294.1 - 2.7e-07 30.6 10.0 6.3e-07 29.4 10.0 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MaoC_dehydrat_N PF13452.6 KXH39295.1 - 0.0038 17.4 0.0 0.017 15.2 0.0 2.0 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase DUF1929 PF09118.11 KXH39295.1 - 0.14 12.5 0.0 0.34 11.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1929) FAD_binding_3 PF01494.19 KXH39296.1 - 6.4e-11 42.1 0.2 3.5e-10 39.6 0.2 1.8 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KXH39296.1 - 0.0038 17.4 0.2 0.0088 16.3 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXH39296.1 - 0.019 14.2 1.1 0.06 12.6 1.1 1.8 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXH39296.1 - 0.045 13.3 0.3 0.24 10.9 0.3 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase 3HCDH_N PF02737.18 KXH39296.1 - 0.057 13.3 0.1 0.082 12.8 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.18 KXH39296.1 - 0.068 13.4 0.1 0.14 12.5 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain Shikimate_DH PF01488.20 KXH39296.1 - 0.08 13.0 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.24 KXH39296.1 - 0.16 11.0 0.6 0.28 10.2 0.6 1.3 1 0 0 1 1 1 0 FAD binding domain ApbA PF02558.16 KXH39296.1 - 0.17 11.5 0.1 0.34 10.5 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Lactamase_B PF00753.27 KXH39297.1 - 4.5e-07 30.1 3.2 7.5e-07 29.3 3.2 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KXH39297.1 - 2.1e-06 27.4 0.1 4.8e-06 26.2 0.1 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KXH39297.1 - 7.1e-06 26.0 0.0 0.00064 19.6 0.0 2.2 2 0 0 2 2 2 2 Beta-lactamase superfamily domain DUF1658 PF07871.11 KXH39297.1 - 0.54 10.3 2.4 1.3 9.1 2.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1658) PHA_synth_III_E PF09712.10 KXH39299.1 - 2.6 7.0 5.5 10 5.1 0.7 2.6 2 1 0 2 2 2 0 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) Pectinesterase PF01095.19 KXH39301.1 - 6.9e-48 162.9 4.6 8.8e-48 162.5 4.6 1.1 1 0 0 1 1 1 1 Pectinesterase MFS_1 PF07690.16 KXH39302.1 - 3.7e-35 121.5 24.2 5.5e-35 120.9 24.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Trp_oprn_chp PF09534.10 KXH39302.1 - 0.015 15.1 4.0 0.64 9.8 0.1 2.8 2 1 1 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Amidase PF01425.21 KXH39303.1 - 8.1e-49 166.8 0.0 3e-45 155.0 0.0 2.1 2 0 0 2 2 2 2 Amidase Pkinase PF00069.25 KXH39305.1 - 1.2e-23 83.8 0.0 2.8e-13 49.8 0.0 2.5 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXH39305.1 - 4.3e-10 39.3 0.9 0.024 14.0 0.0 3.6 4 0 0 4 4 4 3 Protein tyrosine kinase Kinase-like PF14531.6 KXH39305.1 - 0.0081 15.5 0.0 3.6 6.8 0.0 2.7 3 0 0 3 3 3 2 Kinase-like APH PF01636.23 KXH39305.1 - 0.085 12.8 0.0 0.28 11.1 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family TrkA_TMD PF18613.1 KXH39305.1 - 2.4 7.6 4.1 4.8 6.7 4.1 1.4 1 0 0 1 1 1 0 Tyrosine kinase receptor A trans-membrane domain MFS_1 PF07690.16 KXH39306.1 - 3.2e-34 118.4 29.9 3.2e-34 118.4 29.9 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily TMEM100 PF16311.5 KXH39306.1 - 0.15 11.6 0.6 14 5.3 0.0 2.4 2 0 0 2 2 2 0 Transmembrane protein 100 DUF4231 PF14015.6 KXH39306.1 - 3.6 8.1 5.9 10 6.7 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) Laminin_B PF00052.18 KXH39307.1 - 0.091 12.7 0.1 21 5.0 0.0 3.0 3 0 0 3 3 3 0 Laminin B (Domain IV) dCMP_cyt_deam_1 PF00383.23 KXH39308.1 - 5.9e-08 32.5 0.0 7.3e-08 32.2 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KXH39308.1 - 7.1e-07 29.1 0.0 7.9e-07 28.9 0.0 1.1 1 0 0 1 1 1 1 MafB19-like deaminase Terpene_synth_C PF03936.16 KXH39309.1 - 2e-08 33.9 0.1 2.7e-08 33.5 0.1 1.1 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain p450 PF00067.22 KXH39310.1 - 6e-65 219.8 0.0 7.7e-65 219.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Tannase PF07519.11 KXH39311.1 - 7.2e-114 381.3 0.2 8.6e-114 381.0 0.2 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Hydrolase_4 PF12146.8 KXH39311.1 - 0.0075 15.6 0.0 0.53 9.5 0.0 2.4 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KXH39311.1 - 0.025 14.2 0.3 0.13 11.9 0.1 1.9 2 0 0 2 2 2 0 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KXH39311.1 - 0.084 12.3 0.8 1.6 8.1 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family Ank_2 PF12796.7 KXH39312.1 - 7.9e-64 212.2 0.0 9.4e-18 64.6 0.0 9.9 4 3 7 11 11 11 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXH39312.1 - 1.5e-45 153.0 9.6 4.4e-07 30.3 0.1 12.6 8 3 3 12 12 12 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXH39312.1 - 7.4e-43 144.1 6.0 4.7e-06 26.8 0.0 14.0 11 2 4 15 15 15 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXH39312.1 - 9.3e-41 133.2 12.0 3.5e-05 23.9 0.0 15.6 18 0 0 18 18 17 8 Ankyrin repeat Ank PF00023.30 KXH39312.1 - 6.6e-38 127.5 13.6 1.1e-05 25.6 0.0 15.2 16 0 0 16 16 16 7 Ankyrin repeat NACHT PF05729.12 KXH39312.1 - 8e-07 29.1 0.0 2.5e-06 27.5 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA PF00004.29 KXH39312.1 - 0.0033 17.9 0.0 0.25 11.8 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KXH39312.1 - 0.0055 17.1 0.0 0.018 15.5 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain Bac_DnaA PF00308.18 KXH39312.1 - 0.099 12.5 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Bacterial dnaA protein IstB_IS21 PF01695.17 KXH39312.1 - 0.14 11.9 0.1 0.32 10.7 0.1 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein TsaE PF02367.17 KXH39312.1 - 0.16 12.0 0.0 0.49 10.4 0.0 1.8 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ResIII PF04851.15 KXH39312.1 - 0.19 11.7 0.0 1.1 9.2 0.0 2.0 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit XPG_I PF00867.18 KXH39313.1 - 1.3e-30 105.5 1.2 2.2e-30 104.9 0.0 1.9 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.17 KXH39313.1 - 2.2e-29 101.9 0.0 5.6e-29 100.6 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain 5_3_exonuc PF01367.20 KXH39313.1 - 6.2e-06 26.7 0.3 0.00012 22.6 0.0 2.8 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold HHH_2 PF12826.7 KXH39313.1 - 0.065 13.3 0.0 0.19 11.8 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix motif Acyl-CoA_dh_1 PF00441.24 KXH39314.1 - 3.7e-41 140.8 0.3 5.4e-41 140.3 0.3 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KXH39314.1 - 2.5e-20 72.5 0.1 4.2e-20 71.8 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.28 KXH39314.1 - 4.6e-20 71.5 0.4 8.2e-20 70.7 0.4 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.16 KXH39314.1 - 1.2e-17 64.5 0.0 2.6e-17 63.5 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KXH39314.1 - 9.2e-08 32.4 0.0 1.5e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain SUIM_assoc PF16619.5 KXH39338.1 - 0.0088 16.1 1.3 0.028 14.5 0.3 2.4 1 1 1 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 DUF2012 PF09430.10 KXH39339.1 - 2.6e-21 76.0 0.0 3.9e-21 75.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) FAP PF07174.11 KXH39339.1 - 0.79 9.1 3.3 1.1 8.7 3.3 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Cys_Met_Meta_PP PF01053.20 KXH39340.1 - 1.6e-150 500.9 0.0 1.8e-150 500.7 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 KXH39340.1 - 1e-12 48.1 0.3 1.8e-12 47.3 0.3 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 KXH39340.1 - 1.5e-10 40.8 0.0 2.4e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KXH39340.1 - 2.3e-08 33.4 0.3 4.2e-08 32.5 0.3 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KXH39340.1 - 4e-07 29.6 0.0 8e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.11 KXH39340.1 - 0.00015 20.4 0.1 0.00022 19.9 0.1 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase SepSecS PF05889.13 KXH39340.1 - 0.015 14.0 0.0 0.022 13.5 0.0 1.1 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS CPSase_L_D2 PF02786.17 KXH39340.1 - 0.14 11.7 0.1 0.25 10.8 0.1 1.4 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain Asparaginase_C PF17763.1 KXH39340.1 - 0.16 12.2 0.0 0.39 11.0 0.0 1.6 1 0 0 1 1 1 0 Glutaminase/Asparaginase C-terminal domain GDC-P PF02347.16 KXH39340.1 - 0.18 10.6 0.0 0.25 10.1 0.0 1.1 1 0 0 1 1 1 0 Glycine cleavage system P-protein MARVEL PF01284.23 KXH39341.1 - 1.3e-16 60.9 14.6 1.7e-16 60.6 14.6 1.1 1 0 0 1 1 1 1 Membrane-associating domain AMP-binding PF00501.28 KXH39342.1 - 2.2e-86 290.1 0.0 2.7e-86 289.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme WD40 PF00400.32 KXH39343.1 - 0.00036 21.3 8.5 5.1 8.1 0.0 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat Lipase_C PF18067.1 KXH39343.1 - 0.093 13.3 0.1 0.32 11.6 0.1 1.9 1 0 0 1 1 1 0 Lipase C-terminal domain RRM_1 PF00076.22 KXH39344.1 - 1.2e-07 31.5 0.1 3.9e-07 29.8 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CTD_bind PF04818.13 KXH39344.1 - 0.00034 21.4 0.0 0.00094 20.0 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase II-binding domain. Citrate_synt PF00285.21 KXH39345.1 - 1.1e-101 340.5 0.0 1.5e-101 340.1 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Eclosion PF04736.12 KXH39345.1 - 0.032 13.9 0.0 0.07 12.8 0.0 1.5 1 0 0 1 1 1 0 Eclosion hormone Mito_carr PF00153.27 KXH39346.1 - 6.9e-28 96.4 4.0 7e-13 48.3 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein E1-E2_ATPase PF00122.20 KXH39348.1 - 4.1e-49 166.6 4.6 4.1e-49 166.6 4.6 2.7 4 0 0 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 KXH39348.1 - 3e-17 63.6 0.1 9.6e-17 62.0 0.1 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KXH39348.1 - 9.3e-09 34.9 0.1 1.9e-08 33.9 0.1 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KXH39348.1 - 0.0022 17.8 0.1 0.0046 16.7 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KXH39348.1 - 0.034 14.2 0.0 0.066 13.3 0.0 1.4 1 0 0 1 1 1 0 Cation transport ATPase (P-type) O-antigen_lig PF13425.6 KXH39348.1 - 0.1 11.4 4.9 0.26 10.1 4.9 1.6 1 0 0 1 1 1 0 O-antigen ligase like membrane protein DUF2613 PF11021.8 KXH39348.1 - 9.4 6.4 7.7 17 5.6 0.4 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) ABM PF03992.16 KXH39349.1 - 0.00011 22.2 0.2 0.00015 21.8 0.2 1.3 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Arrestin_C PF02752.22 KXH39349.1 - 0.044 14.2 0.0 0.048 14.1 0.0 1.1 1 0 0 1 1 1 0 Arrestin (or S-antigen), C-terminal domain DUF3425 PF11905.8 KXH39352.1 - 6.3e-21 74.6 2.8 9.6e-21 74.0 2.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 KXH39352.1 - 0.011 15.8 11.0 0.021 14.9 7.8 2.3 1 1 1 2 2 2 0 bZIP transcription factor TPR_21 PF09976.9 KXH39352.1 - 0.22 11.2 2.3 0.4 10.3 2.3 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat-like domain GIT_CC PF16559.5 KXH39352.1 - 0.26 11.2 2.7 0.47 10.4 2.7 1.4 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor Spindle_Spc25 PF08234.12 KXH39353.1 - 1.3e-25 89.4 0.1 3.4e-25 88.0 0.1 1.8 1 0 0 1 1 1 1 Chromosome segregation protein Spc25 DUF4407 PF14362.6 KXH39353.1 - 0.067 12.5 11.3 0.092 12.1 11.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Atg14 PF10186.9 KXH39353.1 - 0.15 11.1 12.2 0.25 10.4 12.2 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 FapA PF03961.13 KXH39353.1 - 0.47 9.0 7.8 0.65 8.5 7.8 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A UPF0242 PF06785.11 KXH39353.1 - 0.79 9.8 12.1 1.3 9.1 12.1 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Lebercilin PF15619.6 KXH39353.1 - 3.8 7.1 28.1 1.3 8.6 4.7 2.6 2 1 1 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease Tho2 PF11262.8 KXH39353.1 - 7.4 5.7 12.4 11 5.1 12.0 1.5 1 1 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 MFS_1 PF07690.16 KXH39354.1 - 1.3e-24 86.8 23.4 1.5e-24 86.6 20.4 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH39354.1 - 3.9e-07 29.3 19.9 0.00035 19.6 0.5 3.3 2 1 1 3 3 3 2 Sugar (and other) transporter DUF5389 PF17364.2 KXH39354.1 - 0.0029 17.6 0.5 0.0029 17.6 0.5 2.3 2 1 0 2 2 2 1 Family of unknown function (DUF5389) TssN PF17555.2 KXH39354.1 - 0.24 10.7 2.7 0.57 9.5 2.7 1.7 1 0 0 1 1 1 0 Type VI secretion system, TssN Neurensin PF14927.6 KXH39354.1 - 2.1 8.1 5.1 0.63 9.7 1.3 2.2 2 0 0 2 2 2 0 Neurensin SPX PF03105.19 KXH39355.1 - 7.4e-41 141.3 0.0 5.1e-28 99.1 0.0 2.3 1 1 1 2 2 2 2 SPX domain Na_sulph_symp PF00939.19 KXH39355.1 - 4.6e-36 124.9 40.0 1e-35 123.7 40.0 1.5 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region MFS_1 PF07690.16 KXH39355.1 - 2.5e-35 122.1 17.9 2.5e-35 122.1 17.9 3.7 2 1 0 3 3 3 1 Major Facilitator Superfamily CitMHS PF03600.16 KXH39355.1 - 2e-27 96.2 37.6 2e-27 96.2 37.6 3.0 3 1 0 3 3 3 1 Citrate transporter Sugar_tr PF00083.24 KXH39355.1 - 1.2e-06 27.7 5.8 1.2e-06 27.7 5.8 3.1 1 1 1 2 2 2 1 Sugar (and other) transporter Sporozoite_P67 PF05642.11 KXH39355.1 - 0.62 8.1 5.9 1.4 7.0 5.8 1.4 1 1 0 1 1 1 0 Sporozoite P67 surface antigen Vps39_1 PF10366.9 KXH39356.1 - 4.2e-33 113.9 0.2 7.3e-32 109.9 0.0 3.2 5 0 0 5 5 5 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.9 KXH39356.1 - 1e-29 103.1 0.0 3e-29 101.6 0.0 1.9 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.22 KXH39356.1 - 1.4e-18 67.5 0.0 3.2e-18 66.3 0.0 1.5 1 1 0 1 1 1 1 CNH domain Clathrin PF00637.20 KXH39356.1 - 1.7e-07 31.2 0.5 0.00016 21.6 0.7 3.0 3 0 0 3 3 3 2 Region in Clathrin and VPS Clathrin_H_link PF13838.6 KXH39356.1 - 0.09 12.7 0.0 1.2 9.1 0.0 2.5 2 0 0 2 2 2 0 Clathrin-H-link TPR_1 PF00515.28 KXH39356.1 - 2 8.4 7.0 5 7.1 0.2 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat Gon7 PF08738.10 KXH39357.1 - 1.4e-10 41.2 4.0 4.6e-10 39.5 0.7 2.1 1 1 1 2 2 2 1 Gon7 family Spc7 PF08317.11 KXH39357.1 - 0.057 12.3 0.9 0.069 12.0 0.9 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Dot_icm_IcmQ PF09475.10 KXH39357.1 - 0.1 12.1 0.1 0.13 11.8 0.1 1.2 1 0 0 1 1 1 0 Dot/Icm secretion system protein (dot_icm_IcmQ) HbrB PF08539.11 KXH39358.1 - 8.2e-56 188.6 0.8 1.7e-55 187.6 0.0 2.0 2 0 0 2 2 2 1 HbrB-like Dus PF01207.17 KXH39360.1 - 2.9e-55 187.5 0.0 1.1e-54 185.6 0.0 1.9 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) Peptidase_U4 PF03419.13 KXH39361.1 - 2.7 7.2 5.3 3.6 6.8 5.3 1.2 1 0 0 1 1 1 0 Sporulation factor SpoIIGA DUF3176 PF11374.8 KXH39362.1 - 2.1e-32 111.5 0.9 6.8e-32 109.9 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) His_biosynth PF00977.21 KXH39363.1 - 2.7e-35 121.9 0.0 3.2e-35 121.7 0.0 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein Ribul_P_3_epim PF00834.19 KXH39363.1 - 0.057 12.8 0.0 0.093 12.1 0.0 1.3 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family Anillin PF08174.11 KXH39364.1 - 3.4e-15 56.7 0.0 1e-14 55.2 0.0 1.8 1 0 0 1 1 1 1 Cell division protein anillin PH PF00169.29 KXH39364.1 - 5.2e-08 33.4 0.0 1.8e-07 31.6 0.0 2.0 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KXH39364.1 - 0.16 12.4 0.7 2.3 8.7 0.0 2.7 2 0 0 2 2 2 0 Pleckstrin homology domain DUF1899 PF08953.11 KXH39365.1 - 1.7e-33 114.3 0.0 4.1e-33 113.1 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 KXH39365.1 - 1.6e-18 66.3 0.1 3.2e-18 65.4 0.1 1.5 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 KXH39365.1 - 3.4e-17 62.5 5.8 4.8e-06 27.2 0.5 4.4 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXH39365.1 - 1.5e-08 34.8 0.0 0.0017 18.6 0.0 4.0 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KXH39365.1 - 0.00053 18.8 0.2 0.57 8.8 0.2 2.2 1 1 1 2 2 2 2 Nucleoporin Nup120/160 eIF2A PF08662.11 KXH39365.1 - 0.033 14.1 0.0 0.13 12.1 0.0 1.8 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A DUF16 PF01519.16 KXH39365.1 - 0.091 13.3 1.2 0.2 12.2 1.2 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF16 SlyX PF04102.12 KXH39365.1 - 0.39 11.4 7.4 0.62 10.7 2.2 2.5 2 0 0 2 2 2 0 SlyX ATG16 PF08614.11 KXH39365.1 - 3.5 7.8 10.0 0.56 10.4 6.2 1.6 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF4602 PF15375.6 KXH39366.1 - 0.028 14.8 2.7 0.028 14.8 2.7 4.5 3 1 2 5 5 5 0 Domain of unknown function (DUF4602) CNDH2_C PF16858.5 KXH39366.1 - 1.8 8.3 18.1 0.17 11.7 13.1 1.7 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term STE PF02200.16 KXH39367.1 - 2.1e-56 189.1 0.1 3.4e-56 188.4 0.1 1.4 1 0 0 1 1 1 1 STE like transcription factor zf-C2H2 PF00096.26 KXH39367.1 - 0.00091 19.6 4.2 0.0025 18.2 4.2 1.8 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXH39367.1 - 0.031 15.1 2.4 0.099 13.5 2.4 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger E1-E2_ATPase PF00122.20 KXH39369.1 - 5.3e-37 127.1 1.7 8.6e-36 123.1 0.1 3.3 3 1 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 KXH39369.1 - 1.5e-16 61.4 0.1 2.9e-16 60.4 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KXH39369.1 - 3.1e-10 39.6 0.0 8.5e-10 38.2 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KXH39369.1 - 0.0038 17.0 0.0 0.0069 16.1 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase FOXO_KIX_bdg PF16675.5 KXH39370.1 - 0.1 12.9 0.0 0.13 12.5 0.0 1.4 1 1 0 1 1 1 0 KIX-binding domain of forkhead box O, CR2 SMC_N PF02463.19 KXH39371.1 - 5.8e-64 215.5 5.2 1.1e-63 214.7 5.2 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KXH39371.1 - 1.5e-27 96.2 0.0 5e-27 94.5 0.0 2.0 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 KXH39371.1 - 8.8e-14 52.0 16.4 3.8e-09 36.8 1.1 4.2 3 2 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KXH39371.1 - 6.5e-07 29.4 23.3 6.5e-07 29.4 23.3 4.7 2 2 0 2 2 2 1 AAA ATPase domain SbcCD_C PF13558.6 KXH39371.1 - 0.00024 21.2 0.6 0.0013 19.0 0.0 2.6 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 KXH39371.1 - 0.00085 19.9 57.0 0.00085 19.9 57.0 7.9 2 2 2 4 4 2 1 AAA domain AAA_29 PF13555.6 KXH39371.1 - 0.0034 17.1 0.0 0.0091 15.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Laminin_II PF06009.12 KXH39371.1 - 0.007 16.4 1.4 0.007 16.4 1.4 8.4 4 2 4 9 9 9 1 Laminin Domain II BRE1 PF08647.11 KXH39371.1 - 0.0074 16.3 4.6 0.0074 16.3 4.6 9.5 5 2 4 9 9 9 3 BRE1 E3 ubiquitin ligase BLOC1_2 PF10046.9 KXH39371.1 - 0.017 15.4 2.3 0.017 15.4 2.3 8.3 6 3 3 10 10 10 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DEAD PF00270.29 KXH39371.1 - 0.15 11.8 3.5 2.1 8.1 0.0 3.8 3 1 0 3 3 3 0 DEAD/DEAH box helicase ApoC-I PF04691.12 KXH39371.1 - 0.36 10.8 4.4 6.1 6.9 0.6 3.4 2 0 0 2 2 2 0 Apolipoprotein C-I (ApoC-1) ABC_tran PF00005.27 KXH39371.1 - 0.55 10.8 0.0 0.55 10.8 0.0 6.6 3 2 0 4 4 3 0 ABC transporter Hydantoinase_B PF02538.14 KXH39371.1 - 0.76 8.1 2.6 1.5 7.1 2.6 1.4 1 0 0 1 1 1 0 Hydantoinase B/oxoprolinase FtsK_SpoIIIE PF01580.18 KXH39371.1 - 1.8 7.8 0.0 1.8 7.8 0.0 4.2 4 0 0 4 4 4 0 FtsK/SpoIIIE family DUF3535 PF12054.8 KXH39372.1 - 5.9e-123 411.3 0.0 5.4e-122 408.2 0.0 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF3535) SNF2_N PF00176.23 KXH39372.1 - 2.5e-64 217.2 0.0 5.1e-64 216.2 0.0 1.5 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KXH39372.1 - 9.9e-19 67.7 0.0 2.5e-18 66.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT PF02985.22 KXH39372.1 - 3.5e-16 57.9 2.8 0.0066 16.6 0.0 8.4 8 0 0 8 8 8 4 HEAT repeat HEAT_2 PF13646.6 KXH39372.1 - 8.9e-08 32.4 8.4 0.0001 22.6 0.0 6.3 7 0 0 7 7 7 1 HEAT repeats Vac14_Fab1_bd PF12755.7 KXH39372.1 - 8.2e-07 29.5 0.3 0.24 12.0 0.0 4.1 2 1 1 3 3 3 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 KXH39372.1 - 0.017 15.6 8.7 8.2 7.1 0.0 6.3 7 0 0 7 7 7 0 HEAT-like repeat ERCC3_RAD25_C PF16203.5 KXH39372.1 - 0.15 11.2 0.0 0.31 10.2 0.0 1.4 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase RE_AccI PF09545.10 KXH39372.1 - 0.19 10.6 0.0 0.31 10.0 0.0 1.2 1 0 0 1 1 1 0 AccI restriction endonuclease Adaptin_N PF01602.20 KXH39372.1 - 0.35 9.4 2.0 9 4.7 0.1 3.2 3 0 0 3 3 3 0 Adaptin N terminal region CDC37_N PF03234.14 KXH39373.1 - 2e-49 167.8 1.1 2e-49 167.8 1.1 3.7 3 2 1 4 4 4 1 Cdc37 N terminal kinase binding CDC37_M PF08565.11 KXH39373.1 - 3.8e-40 136.5 0.2 1e-39 135.1 0.2 1.8 1 0 0 1 1 1 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.10 KXH39373.1 - 1.5e-32 111.7 0.7 1.5e-32 111.7 0.7 2.4 2 1 0 2 2 2 1 Cdc37 C terminal domain DUF2859 PF11072.8 KXH39373.1 - 0.058 13.1 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2859) MecA_N PF05223.11 KXH39373.1 - 4 7.7 8.1 0.43 10.9 0.2 3.2 3 1 2 5 5 5 0 NTF2-like N-terminal transpeptidase domain Peptidase_C48 PF02902.19 KXH39374.1 - 6e-15 55.7 0.0 1.5e-14 54.4 0.0 1.6 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Arm-DNA-bind_4 PF14657.6 KXH39375.1 - 0.15 11.9 0.4 0.47 10.2 0.4 1.8 1 0 0 1 1 1 0 Arm DNA-binding domain Spc7 PF08317.11 KXH39375.1 - 0.31 9.9 10.8 0.66 8.8 10.8 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4407 PF14362.6 KXH39375.1 - 0.34 10.2 7.6 0.91 8.8 7.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) E2R135 PF11570.8 KXH39375.1 - 0.84 9.9 9.7 0.22 11.8 2.8 2.6 2 0 0 2 2 2 0 Coiled-coil receptor-binding R-domain of colicin E2 ADIP PF11559.8 KXH39375.1 - 0.9 9.6 15.0 1.3 9.1 4.8 2.5 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding ERM PF00769.19 KXH39375.1 - 1.1 9.0 18.0 0.026 14.3 7.8 2.2 2 0 0 2 2 2 0 Ezrin/radixin/moesin family YabA PF06156.13 KXH39375.1 - 3.3 8.4 7.6 30 5.3 2.2 2.5 1 1 1 2 2 2 0 Initiation control protein YabA Atg14 PF10186.9 KXH39375.1 - 9.5 5.2 12.7 25 3.8 12.3 1.6 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 PIP5K PF01504.18 KXH39376.1 - 8e-46 156.5 0.0 2.2e-44 151.8 0.0 2.0 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase HET PF06985.11 KXH39377.1 - 2.4e-17 63.7 0.0 4.1e-17 62.9 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ACOX PF01756.19 KXH39378.1 - 2.7e-47 160.7 0.6 4.8e-47 159.8 0.6 1.4 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 KXH39378.1 - 4.1e-29 101.7 0.6 8.6e-29 100.6 0.2 1.8 2 0 0 2 2 2 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 KXH39378.1 - 4.4e-13 49.2 0.0 1.9e-12 47.2 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 KXH39378.1 - 2e-05 24.9 0.6 0.0041 17.3 0.0 3.0 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, C-terminal domain AAA_18 PF13238.6 KXH39379.1 - 0.11 13.0 0.1 0.22 12.1 0.1 1.6 1 1 0 1 1 1 0 AAA domain Pec_lyase_C PF00544.19 KXH39380.1 - 2.2e-41 141.7 9.5 3.5e-41 141.1 9.5 1.3 1 0 0 1 1 1 1 Pectate lyase Gly_transf_sug PF04488.15 KXH39381.1 - 6.6e-12 45.9 1.4 9.1e-12 45.5 0.2 1.9 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif DUF5527 PF17665.1 KXH39381.1 - 0.037 13.5 0.1 0.078 12.5 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5527) Caps_synth PF05704.12 KXH39381.1 - 0.99 8.7 3.9 0.31 10.4 0.0 2.0 2 0 0 2 2 2 0 Capsular polysaccharide synthesis protein Acyl_transf_3 PF01757.22 KXH39382.1 - 4e-37 128.0 30.4 4.6e-37 127.9 30.4 1.1 1 0 0 1 1 1 1 Acyltransferase family p450 PF00067.22 KXH39385.1 - 4.1e-31 108.2 0.0 5e-31 108.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PLCC PF14466.6 KXH39387.1 - 0.011 15.9 0.1 0.016 15.4 0.1 1.2 1 0 0 1 1 1 0 PLAT/LH2 and C2-like Ca2+-binding lipoprotein Cation_ATPase_C PF00689.21 KXH39388.1 - 2.8e-45 154.3 6.5 2.8e-45 154.3 6.5 2.6 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KXH39388.1 - 1e-34 119.7 1.3 1e-34 119.7 1.3 2.9 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 KXH39388.1 - 9.9e-22 78.3 4.6 3e-21 76.7 4.6 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KXH39388.1 - 1.6e-21 76.2 0.0 3.1e-21 75.2 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KXH39388.1 - 3.8e-12 45.7 0.0 3.2e-10 39.6 0.0 2.9 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KXH39388.1 - 0.00033 20.5 0.3 0.00097 18.9 0.1 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Sugar_tr PF00083.24 KXH39389.1 - 7.4e-115 384.4 21.9 9.5e-115 384.0 21.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH39389.1 - 1.7e-26 93.0 51.8 1.3e-24 86.8 22.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2070 PF09843.9 KXH39389.1 - 2.2 6.4 4.2 4.2 5.5 4.2 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) GATA PF00320.27 KXH39391.1 - 2.4e-13 49.5 1.5 4.3e-13 48.6 1.5 1.4 1 0 0 1 1 1 1 GATA zinc finger Zn-ribbon_8 PF09723.10 KXH39391.1 - 0.048 13.8 0.3 0.091 12.9 0.3 1.5 1 0 0 1 1 1 0 Zinc ribbon domain CHZ PF09649.10 KXH39391.1 - 0.085 12.3 0.2 0.18 11.3 0.2 1.5 1 0 0 1 1 1 0 Histone chaperone domain CHZ zf-C2H2_3 PF13878.6 KXH39391.1 - 0.22 11.4 2.4 0.66 9.9 0.0 2.7 3 0 0 3 3 3 0 zinc-finger of acetyl-transferase ESCO DUF3425 PF11905.8 KXH39444.1 - 4.3e-17 62.2 0.4 7.8e-17 61.4 0.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) Tma16 PF11176.8 KXH39444.1 - 0.089 12.7 3.3 0.17 11.8 3.3 1.3 1 0 0 1 1 1 0 Translation machinery-associated protein 16 bZIP_1 PF00170.21 KXH39444.1 - 0.27 11.4 17.4 6.4 7.0 17.4 2.2 1 1 0 1 1 1 0 bZIP transcription factor FapA PF03961.13 KXH39444.1 - 0.38 9.3 0.6 0.63 8.6 0.4 1.3 2 0 0 2 2 2 0 Flagellar Assembly Protein A TFIIA PF03153.13 KXH39445.1 - 0.18 11.7 2.9 0.23 11.4 2.9 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Tannase PF07519.11 KXH39476.1 - 2.8e-93 313.4 0.4 3.3e-93 313.1 0.4 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Hydrolase_4 PF12146.8 KXH39476.1 - 0.03 13.6 0.0 0.38 10.0 0.0 2.1 2 0 0 2 2 2 0 Serine aminopeptidase, S33 V-set_CD47 PF08204.11 KXH39477.1 - 0.043 13.8 0.0 0.076 13.0 0.0 1.4 1 0 0 1 1 1 0 CD47 immunoglobulin-like domain Fungal_trans_2 PF11951.8 KXH39478.1 - 2.9e-10 39.5 0.2 9.3e-10 37.9 0.3 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH39478.1 - 2.9e-06 27.3 9.2 7e-06 26.1 9.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tyr_Deacylase PF02580.16 KXH39478.1 - 0.063 13.8 0.0 0.13 12.8 0.0 1.5 1 0 0 1 1 1 0 D-Tyr-tRNA(Tyr) deacylase Glyco_hydro_61 PF03443.14 KXH39479.1 - 1.5e-65 221.0 0.0 2.4e-65 220.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.18 KXH39479.1 - 2.2e-12 46.7 14.0 6.9e-12 45.1 14.0 1.9 1 0 0 1 1 1 1 Fungal cellulose binding domain MFS_1 PF07690.16 KXH39481.1 - 6.4e-26 91.1 45.5 3.7e-23 82.0 34.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2678 PF10856.8 KXH39481.1 - 0.07 13.1 0.1 0.23 11.4 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2678) SIR2 PF02146.17 KXH39482.1 - 7.2e-20 71.6 0.0 1.8e-09 37.8 0.2 3.2 2 1 0 2 2 2 2 Sir2 family MRP-L20 PF12824.7 KXH39492.1 - 6.1e-12 46.0 1.4 7.3e-12 45.7 1.4 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 DUF3484 PF11983.8 KXH39493.1 - 0.47 11.6 2.3 0.79 10.9 0.0 2.6 3 1 0 3 3 3 0 Membrane-attachment and polymerisation-promoting switch OB_NTP_bind PF07717.16 KXH39494.1 - 7.3e-21 74.3 0.0 1.8e-20 73.1 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 KXH39494.1 - 4.6e-19 68.7 0.1 4.6e-19 68.7 0.1 3.7 3 1 0 3 3 3 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KXH39494.1 - 9.6e-15 54.9 0.2 5.1e-14 52.6 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 KXH39494.1 - 2.8e-05 24.4 1.0 9.6e-05 22.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain DEAD PF00270.29 KXH39494.1 - 3.2e-05 23.8 0.0 8.2e-05 22.4 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SSE PF00437.20 KXH39494.1 - 0.0019 17.3 0.0 0.0047 16.0 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_30 PF13604.6 KXH39494.1 - 0.0054 16.5 0.0 0.0054 16.5 0.0 1.8 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.22 KXH39494.1 - 0.012 15.3 0.2 0.031 13.9 0.2 1.7 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_14 PF13173.6 KXH39494.1 - 0.28 11.2 2.5 2.9 7.9 0.1 3.2 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KXH39494.1 - 0.41 11.2 0.0 0.41 11.2 0.0 2.4 3 1 0 3 3 3 0 ABC transporter DnaJ PF00226.31 KXH39495.1 - 5.8e-26 90.4 3.1 9.3e-26 89.7 3.1 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_C PF01556.18 KXH39495.1 - 2.4e-24 86.1 0.0 3.5e-24 85.6 0.0 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 KXH39495.1 - 6.8e-13 48.8 18.0 1.2e-12 48.0 18.0 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.19 KXH39495.1 - 0.0013 18.7 7.1 0.22 11.6 1.2 2.3 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Anti-TRAP PF15777.5 KXH39495.1 - 0.21 11.6 8.6 2.8 8.0 0.6 2.4 2 0 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein TackOD1 PF18551.1 KXH39495.1 - 2.1 8.0 5.3 2.6 7.7 0.5 2.2 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 DZR PF12773.7 KXH39495.1 - 8.1 6.6 8.2 22 5.2 8.2 1.7 1 1 0 1 1 1 0 Double zinc ribbon DUF3824 PF12868.7 KXH39496.1 - 5.7e-06 27.1 35.2 1e-05 26.3 11.9 11.5 6 4 5 11 11 11 5 Domain of unknwon function (DUF3824) Phage_holin_3_3 PF16083.5 KXH39496.1 - 0.62 10.2 2.6 7.8 6.7 0.7 3.3 2 1 1 3 3 3 0 LydA holin phage, holin superfamily III MFS_1 PF07690.16 KXH39497.1 - 1.1e-43 149.6 40.1 1.1e-43 149.6 40.1 1.8 2 1 0 2 2 2 1 Major Facilitator Superfamily GPI-anchored PF10342.9 KXH39498.1 - 3.4e-05 24.5 1.0 3.4e-05 24.5 1.0 2.0 1 1 1 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4690 PF15756.5 KXH39498.1 - 0.00069 20.2 1.3 0.0016 19.0 1.3 1.6 1 0 0 1 1 1 1 Small Novel Rich in Cartilage DUF4644 PF15486.6 KXH39498.1 - 0.0092 15.7 0.8 0.015 15.1 0.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4644) Mucin15 PF15672.5 KXH39498.1 - 0.015 14.8 2.7 0.022 14.3 2.7 1.2 1 0 0 1 1 1 0 Cell-membrane associated Mucin15 Podoplanin PF05808.11 KXH39498.1 - 0.028 14.5 1.3 0.048 13.8 1.3 1.4 1 0 0 1 1 1 0 Podoplanin Sacchrp_dh_C PF16653.5 KXH39499.1 - 3.3e-82 276.6 0.0 5.5e-82 275.8 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 KXH39499.1 - 1.8e-22 80.0 0.0 2.5e-22 79.5 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 KXH39499.1 - 6.3e-08 32.8 0.0 9.6e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 KXH39499.1 - 0.0053 17.3 0.0 0.0097 16.5 0.0 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_10 PF13460.6 KXH39499.1 - 0.043 13.7 0.0 0.063 13.2 0.0 1.2 1 0 0 1 1 1 0 NAD(P)H-binding TatD_DNase PF01026.21 KXH39500.1 - 1e-41 143.0 0.0 1.2e-41 142.8 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase DUF865 PF05906.11 KXH39500.1 - 0.19 11.6 0.7 0.47 10.3 0.7 1.6 1 0 0 1 1 1 0 Herpesvirus-7 repeat of unknown function (DUF865) HAD_2 PF13419.6 KXH39501.1 - 2.1e-09 37.7 0.0 1.7e-08 34.8 0.0 2.0 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KXH39501.1 - 0.0002 21.7 0.0 0.00079 19.8 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Ten1 PF12658.7 KXH39502.1 - 1.9e-30 105.3 0.0 2.2e-30 105.1 0.0 1.1 1 0 0 1 1 1 1 Telomere capping, CST complex subunit Ten1_2 PF15490.6 KXH39502.1 - 0.00056 19.6 0.0 0.00061 19.5 0.0 1.1 1 0 0 1 1 1 1 Telomere-capping, CST complex subunit Snf7 PF03357.21 KXH39503.1 - 1e-29 103.3 18.6 1e-29 103.3 18.6 2.0 1 1 1 2 2 2 2 Snf7 Allexi_40kDa PF05549.11 KXH39503.1 - 0.96 8.9 6.6 1.4 8.4 6.5 1.4 1 1 0 1 1 1 0 Allexivirus 40kDa protein DUF3138 PF11336.8 KXH39503.1 - 3.3 6.2 10.7 0.19 10.3 3.5 2.2 1 1 2 3 3 3 0 Protein of unknown function (DUF3138) 3Beta_HSD PF01073.19 KXH39507.1 - 2.5e-54 184.2 0.0 3.2e-54 183.8 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KXH39507.1 - 2.2e-30 105.9 0.0 2.9e-30 105.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXH39507.1 - 3.6e-22 79.2 0.1 2.6e-21 76.4 0.1 2.1 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KXH39507.1 - 7.5e-17 61.3 0.1 4e-10 39.3 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 KXH39507.1 - 5.7e-13 48.6 0.0 7.7e-13 48.2 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 KXH39507.1 - 5.6e-12 45.9 0.1 9.1e-12 45.2 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KXH39507.1 - 2.7e-09 36.6 0.3 1.1e-07 31.4 0.9 2.7 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.10 KXH39507.1 - 6.1e-08 32.8 0.7 4.1e-07 30.1 0.7 2.1 1 1 0 1 1 1 1 KR domain NmrA PF05368.13 KXH39507.1 - 0.12 12.0 0.3 0.19 11.2 0.3 1.3 1 0 0 1 1 1 0 NmrA-like family TPR_12 PF13424.6 KXH39508.1 - 2.4e-24 85.4 14.2 0.00046 20.4 0.6 7.6 6 1 1 7 7 7 5 Tetratricopeptide repeat TPR_10 PF13374.6 KXH39508.1 - 2.6e-12 46.2 17.1 0.016 15.1 0.1 9.5 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_14 PF13428.6 KXH39508.1 - 9.8e-09 35.3 1.6 2.3 9.3 0.1 7.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 KXH39508.1 - 2.9e-07 30.0 2.5 0.73 10.0 0.0 6.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 KXH39508.1 - 1.9e-05 25.2 5.1 1.3 9.7 0.1 6.1 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.17 KXH39508.1 - 5.7e-05 22.9 2.5 44 4.5 0.0 6.8 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_1 PF00515.28 KXH39508.1 - 0.00046 19.9 0.1 7.2 6.6 0.0 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_4 PF07721.14 KXH39508.1 - 0.00057 20.3 1.3 53 4.9 0.1 6.2 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 KXH39508.1 - 0.0012 18.9 0.6 4.2 7.8 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat NB-ARC PF00931.22 KXH39508.1 - 0.0019 17.4 0.0 0.0071 15.6 0.0 1.9 1 1 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 KXH39508.1 - 0.015 15.7 1.9 0.44 10.9 0.1 3.8 3 1 0 3 3 3 0 AAA ATPase domain ATPase_2 PF01637.18 KXH39508.1 - 0.11 12.4 0.0 0.36 10.7 0.0 1.8 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Abhydrolase_3 PF07859.13 KXH39509.1 - 4.2e-05 23.5 0.1 0.00029 20.8 0.1 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF915 PF06028.11 KXH39509.1 - 8e-05 22.1 0.0 0.00013 21.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Lipase_3 PF01764.25 KXH39509.1 - 0.00045 20.1 0.0 0.002 18.0 0.0 2.0 1 1 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 KXH39509.1 - 0.012 14.9 0.0 0.025 13.8 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KXH39509.1 - 0.016 14.8 0.1 1 9.0 0.0 2.3 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF2974 PF11187.8 KXH39509.1 - 0.033 13.7 0.0 0.054 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Thioesterase PF00975.20 KXH39509.1 - 0.045 13.9 0.0 0.086 12.9 0.0 1.5 1 0 0 1 1 1 0 Thioesterase domain bPH_6 PF10756.9 KXH39509.1 - 0.045 13.8 0.1 35 4.6 0.0 3.3 3 1 1 4 4 4 0 Bacterial PH domain Abhydrolase_6 PF12697.7 KXH39509.1 - 0.089 13.4 0.2 0.12 13.0 0.2 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Sortase PF04203.13 KXH39509.1 - 0.13 12.0 0.0 1 9.2 0.0 2.1 2 0 0 2 2 2 0 Sortase domain Lyase_1 PF00206.20 KXH39510.1 - 4.9e-24 85.3 0.2 9.2e-24 84.4 0.2 1.4 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.6 KXH39510.1 - 2e-11 44.4 0.0 5.5e-11 43.1 0.0 1.8 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal SNCAIP_SNCA_bd PF16700.5 KXH39510.1 - 0.085 12.6 0.1 15 5.4 0.1 2.7 2 0 0 2 2 2 0 Synphilin-1 alpha-Synuclein-binding domain Pup_ligase PF03136.15 KXH39510.1 - 0.11 11.5 0.0 0.22 10.5 0.0 1.4 1 0 0 1 1 1 0 Pup-ligase protein FumaraseC_C PF10415.9 KXH39510.1 - 0.35 11.3 1.8 0.85 10.1 0.0 2.7 3 0 0 3 3 3 0 Fumarase C C-terminus MFS_1 PF07690.16 KXH39511.1 - 5.1e-22 78.3 21.2 5.1e-22 78.3 21.2 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH39511.1 - 9.6e-07 28.0 33.1 0.00026 20.0 33.1 3.2 1 1 0 1 1 1 1 Sugar (and other) transporter Phage_holin_7_1 PF16081.5 KXH39511.1 - 1.5 9.0 7.2 1.1 9.4 0.2 2.4 2 0 0 2 2 2 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family DUF2721 PF11026.8 KXH39511.1 - 2.3 8.1 10.3 5.4 6.9 0.0 4.5 2 1 3 6 6 6 0 Protein of unknown function (DUF2721) TfuA PF07812.12 KXH39513.1 - 0.085 12.6 3.1 0.091 12.5 1.5 1.8 2 0 0 2 2 2 0 TfuA-like protein RasGAP PF00616.19 KXH39516.1 - 3.3e-60 203.4 0.1 1.9e-59 200.9 0.0 2.2 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 KXH39516.1 - 2e-29 102.5 6.1 2e-29 102.5 6.1 2.4 2 0 0 2 2 2 1 RasGAP C-terminus Terpene_synth_C PF03936.16 KXH39517.1 - 0.027 13.8 0.0 0.03 13.6 0.0 1.1 1 0 0 1 1 1 0 Terpene synthase family, metal binding domain Redoxin PF08534.10 KXH39518.1 - 1.2e-24 86.7 0.0 2.4e-24 85.7 0.0 1.5 1 0 0 1 1 1 1 Redoxin IBR PF01485.21 KXH39518.1 - 3.2e-21 75.3 45.3 2.3e-10 40.5 4.7 4.5 3 1 1 4 4 4 3 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 KXH39518.1 - 6.5e-06 25.9 40.2 0.00023 21.0 5.6 4.4 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXH39518.1 - 0.00037 20.8 43.5 0.00071 19.9 7.0 4.0 2 1 1 3 3 3 2 Ring finger domain zf-C3HC4_2 PF13923.6 KXH39518.1 - 0.0043 16.9 42.7 0.0045 16.8 5.4 4.8 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXH39518.1 - 0.022 14.8 34.8 0.058 13.4 5.1 3.8 3 1 0 3 3 3 0 RING-type zinc-finger UN_NPL4 PF11543.8 KXH39518.1 - 0.038 14.5 0.0 0.085 13.4 0.0 1.6 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 HbrB PF08539.11 KXH39518.1 - 0.08 12.9 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 HbrB-like zf-C3HC4_4 PF15227.6 KXH39518.1 - 0.33 11.2 30.5 0.18 12.0 1.4 4.4 3 1 0 3 3 3 0 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 KXH39518.1 - 8.5 6.8 34.1 10 6.5 4.1 3.7 3 0 0 3 3 3 0 RING-H2 zinc finger domain XPG_I PF00867.18 KXH39519.1 - 3.8e-24 84.9 0.0 1.1e-23 83.4 0.0 1.8 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 KXH39519.1 - 1.7e-22 79.8 0.0 4e-22 78.6 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain 5_3_exonuc PF01367.20 KXH39519.1 - 0.00014 22.4 0.1 0.0043 17.6 0.0 2.3 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold XPG_I_2 PF12813.7 KXH39519.1 - 0.00066 19.2 0.0 0.0013 18.3 0.0 1.4 1 0 0 1 1 1 1 XPG domain containing HHH_5 PF14520.6 KXH39519.1 - 0.13 12.9 0.0 16 6.2 0.0 2.9 2 0 0 2 2 2 0 Helix-hairpin-helix domain Tma16 PF11176.8 KXH39520.1 - 2.4e-46 157.2 1.2 2.9e-46 157.0 1.2 1.1 1 0 0 1 1 1 1 Translation machinery-associated protein 16 CHASE7 PF17151.4 KXH39520.1 - 0.017 14.7 0.2 0.024 14.3 0.2 1.2 1 0 0 1 1 1 0 Periplasmic sensor domain baeRF_family6 PF18848.1 KXH39520.1 - 0.084 13.3 0.4 0.11 12.9 0.4 1.3 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 6 MAM33 PF02330.16 KXH39521.1 - 4.3e-77 258.8 1.2 6.4e-77 258.3 1.2 1.3 1 0 0 1 1 1 1 Mitochondrial glycoprotein Lyase_aromatic PF00221.19 KXH39522.1 - 2.5e-153 511.1 9.3 3.3e-153 510.7 9.3 1.1 1 0 0 1 1 1 1 Aromatic amino acid lyase Methyltransf_31 PF13847.6 KXH39523.1 - 4.4e-15 55.8 0.0 9.3e-15 54.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXH39523.1 - 4.1e-14 52.7 0.0 6.5e-14 52.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH39523.1 - 8.8e-14 52.0 0.0 1.9e-13 50.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH39523.1 - 4.1e-12 46.6 0.0 7.3e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH39523.1 - 4.8e-11 43.3 0.0 8.1e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KXH39523.1 - 2e-05 24.1 0.0 5.8e-05 22.6 0.0 1.7 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_2 PF00891.18 KXH39523.1 - 2.6e-05 23.6 0.0 0.00016 21.0 0.0 2.1 2 0 0 2 2 2 1 O-methyltransferase domain MetW PF07021.12 KXH39523.1 - 6.8e-05 22.5 0.0 0.00013 21.7 0.0 1.4 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.14 KXH39523.1 - 0.00011 21.9 0.0 0.00018 21.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.19 KXH39523.1 - 0.00066 19.8 0.0 0.00088 19.4 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase RrnaAD PF00398.20 KXH39523.1 - 0.013 14.5 0.0 0.021 13.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase CMAS PF02353.20 KXH39523.1 - 0.015 14.6 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 KXH39523.1 - 0.02 14.2 0.0 0.032 13.6 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family PCMT PF01135.19 KXH39523.1 - 0.057 13.2 0.0 0.088 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 KXH39523.1 - 0.18 11.2 0.0 0.26 10.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Scytalone_dh PF02982.14 KXH39524.1 - 1.3e-83 278.6 0.3 1.5e-83 278.4 0.3 1.0 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.6 KXH39524.1 - 3.4e-08 33.7 0.1 4.5e-08 33.3 0.1 1.2 1 0 0 1 1 1 1 SnoaL-like domain CAP PF00188.26 KXH39525.1 - 3.8e-21 76.2 2.2 3.8e-21 76.2 2.2 1.6 2 0 0 2 2 2 1 Cysteine-rich secretory protein family MGC-24 PF05283.11 KXH39525.1 - 3.6 8.0 6.6 8.9 6.8 6.6 1.6 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Oxysterol_BP PF01237.18 KXH39527.1 - 1.7e-49 168.6 0.0 3.2e-47 161.2 0.0 2.1 1 1 0 1 1 1 1 Oxysterol-binding protein Tti2 PF10521.9 KXH39528.1 - 2e-21 76.8 0.2 3e-21 76.2 0.2 1.2 1 0 0 1 1 1 1 Tti2 family DUF1844 PF08899.11 KXH39528.1 - 0.028 14.7 0.0 0.058 13.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1844) Syja_N PF02383.18 KXH39529.1 - 8.2e-75 252.1 0.0 1.7e-74 251.0 0.0 1.6 1 0 0 1 1 1 1 SacI homology domain HD_6 PF18019.1 KXH39529.1 - 0.14 12.2 0.6 0.46 10.6 0.1 1.9 2 0 0 2 2 2 0 HD domain zf-C2H2 PF00096.26 KXH39539.1 - 3.8 8.2 25.2 1.2 9.7 0.5 6.1 6 0 0 6 6 6 0 Zinc finger, C2H2 type Methyltransf_11 PF08241.12 KXH39540.1 - 2.5e-13 50.5 0.0 6.8e-13 49.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH39540.1 - 9.4e-06 26.3 0.0 2.7e-05 24.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXH39540.1 - 0.0077 16.1 0.0 0.021 14.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH39540.1 - 0.025 15.3 0.0 0.064 14.0 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 KXH39540.1 - 0.056 12.8 0.0 0.098 12.0 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 KXH39540.1 - 0.076 12.8 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_8 PF05148.15 KXH39540.1 - 0.089 12.6 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Hypothetical methyltransferase SUI1 PF01253.22 KXH39541.1 - 8.2e-26 90.4 0.3 8.2e-26 90.4 0.3 1.9 2 0 0 2 2 2 1 Translation initiation factor SUI1 Img2 PF05046.14 KXH39541.1 - 0.1 12.9 0.6 0.19 12.0 0.1 1.8 2 1 0 2 2 2 0 Mitochondrial large subunit ribosomal protein (Img2) FKBP_N PF01346.18 KXH39541.1 - 1.4 9.9 9.6 4.3 8.4 9.6 1.8 1 1 0 1 1 1 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase Nbl1_Borealin_N PF10444.9 KXH39542.1 - 1.5e-19 69.3 6.3 2.6e-19 68.6 6.3 1.4 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal VWA_2 PF13519.6 KXH39543.1 - 7.8e-27 94.0 0.0 1.7e-26 93.0 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 KXH39543.1 - 5.4e-11 43.0 0.5 7.2e-11 42.6 0.5 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.14 KXH39543.1 - 3.9e-07 30.1 0.0 5.4e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like UIM PF02809.20 KXH39543.1 - 0.019 14.8 0.8 0.057 13.3 0.8 1.9 1 0 0 1 1 1 0 Ubiquitin interaction motif Sybindin PF04099.12 KXH39544.1 - 8.7e-53 178.1 0.0 1e-52 177.8 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 KXH39544.1 - 9.4e-08 32.3 0.1 1.5e-07 31.6 0.1 1.3 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region RNA_pol_Rpb4 PF03874.16 KXH39545.1 - 4.9e-25 88.2 5.2 7.5e-25 87.6 5.2 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb4 EphA2_TM PF14575.6 KXH39546.1 - 0.028 15.3 0.0 0.47 11.4 0.0 2.3 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain CPL PF08144.11 KXH39547.1 - 2e-43 148.1 0.2 5.1e-41 140.4 0.0 4.0 4 1 0 4 4 4 1 CPL (NUC119) domain PUF PF00806.19 KXH39547.1 - 0.089 12.5 0.0 3.9 7.4 0.0 3.6 4 0 0 4 4 4 0 Pumilio-family RNA binding repeat CRR7 PF12095.8 KXH39547.1 - 0.16 12.5 2.2 0.47 10.9 0.5 2.7 3 0 0 3 3 3 0 Protein CHLORORESPIRATORY REDUCTION 7 RRN3 PF05327.11 KXH39547.1 - 2.5 6.6 10.7 0.055 12.0 1.6 2.2 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 RWD PF05773.22 KXH39548.1 - 3.2e-24 85.4 0.6 6.2e-24 84.5 0.6 1.5 1 0 0 1 1 1 1 RWD domain DFRP_C PF16543.5 KXH39548.1 - 3.2e-06 27.5 7.3 3.2e-06 27.5 7.3 2.4 1 1 1 2 2 2 1 DRG Family Regulatory Proteins, Tma46 MRI PF15325.6 KXH39548.1 - 0.076 14.1 2.3 0.17 13.0 2.3 1.6 1 1 0 1 1 1 0 Modulator of retrovirus infection Folliculin PF11704.8 KXH39548.1 - 0.19 11.6 1.0 0.25 11.2 1.0 1.2 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport UNC-79 PF14776.6 KXH39548.1 - 0.24 10.1 1.6 0.3 9.8 1.6 1.2 1 0 0 1 1 1 0 Cation-channel complex subunit UNC-79 TPR_19 PF14559.6 KXH39549.1 - 1.7e-11 44.5 3.5 0.0026 18.2 0.2 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 KXH39549.1 - 2.1e-10 40.0 0.8 9.6e-06 25.4 0.0 5.0 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 KXH39549.1 - 7.8e-10 38.9 5.5 9.4e-05 22.6 0.5 3.9 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KXH39549.1 - 2.7e-09 36.4 9.9 3.7e-06 26.6 0.0 5.3 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_1 PF00515.28 KXH39549.1 - 2.1e-08 33.6 0.1 9.6e-05 22.0 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KXH39549.1 - 2.7e-08 34.3 8.1 0.028 15.1 0.0 5.0 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 KXH39549.1 - 9.2e-07 29.2 9.6 0.1 13.5 0.2 5.3 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 KXH39549.1 - 5.1e-06 26.1 0.1 0.014 15.4 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 KXH39549.1 - 4.3e-05 23.2 6.9 0.027 14.4 0.3 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 KXH39549.1 - 0.00017 21.2 0.0 0.18 11.5 0.0 3.7 3 0 0 3 3 3 1 TPR repeat ANAPC3 PF12895.7 KXH39549.1 - 0.00052 20.2 0.0 9.8 6.5 0.0 3.5 3 1 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_MalT PF17874.1 KXH39549.1 - 0.00059 19.3 1.7 0.13 11.6 0.0 2.5 2 1 0 2 2 2 2 MalT-like TPR region TPR_9 PF13371.6 KXH39549.1 - 0.0084 16.2 4.4 0.72 10.0 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 KXH39549.1 - 0.029 14.7 0.0 1.5e+02 3.1 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 KXH39549.1 - 0.15 12.8 3.6 9.5 7.1 0.0 4.4 5 0 0 5 5 4 0 Tetratricopeptide repeat BTAD PF03704.17 KXH39549.1 - 0.27 11.7 0.2 0.27 11.7 0.2 3.5 3 1 0 3 3 3 0 Bacterial transcriptional activator domain TRP PF06011.12 KXH39550.1 - 5e-37 127.7 25.4 1.2e-35 123.0 25.4 2.2 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 KXH39550.1 - 8.9e-25 87.7 0.0 1.5e-24 87.0 0.0 1.4 1 0 0 1 1 1 1 ML-like domain RFamide_26RFa PF11109.8 KXH39550.1 - 0.028 14.9 1.0 0.12 12.9 0.2 2.3 2 0 0 2 2 2 0 Orexigenic neuropeptide Qrfp/P518 HATPase_c_3 PF13589.6 KXH39551.1 - 5.4e-13 48.9 0.1 1.1e-12 47.9 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KXH39551.1 - 1e-08 35.7 0.1 2.4e-08 34.5 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_mis_repair PF01119.19 KXH39551.1 - 0.00083 19.0 0.0 0.0022 17.7 0.0 1.7 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain Cas_Csy4 PF09618.10 KXH39551.1 - 0.061 13.5 0.6 0.15 12.2 0.6 1.6 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy4) Pox_RNA_Pol_19 PF05320.12 KXH39551.1 - 0.11 12.5 0.6 0.35 10.8 0.0 2.1 2 0 0 2 2 2 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit DMRL_synthase PF00885.19 KXH39552.1 - 2.8e-57 192.5 0.1 3.4e-57 192.2 0.1 1.1 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase RXT2_N PF08595.11 KXH39553.1 - 0.21 11.6 6.8 1.6 8.7 4.6 2.5 2 0 0 2 2 2 0 RXT2-like, N-terminal Cwf_Cwc_15 PF04889.12 KXH39553.1 - 0.46 10.2 20.4 0.44 10.3 15.0 2.4 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein DNA_pol_phi PF04931.13 KXH39553.1 - 2 6.4 8.4 3.5 5.6 8.4 1.3 1 0 0 1 1 1 0 DNA polymerase phi Formyl_trans_N PF00551.19 KXH39555.1 - 5.8e-40 137.0 0.0 6.9e-40 136.7 0.0 1.1 1 0 0 1 1 1 1 Formyl transferase Glyco_trans_4_4 PF13579.6 KXH39555.1 - 0.022 15.2 0.0 0.029 14.8 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain Cation_efflux PF01545.21 KXH39556.1 - 3.5e-23 82.4 11.5 4.9e-23 81.9 11.5 1.2 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KXH39556.1 - 4e-08 33.3 0.0 7.9e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter PI3_PI4_kinase PF00454.27 KXH39557.1 - 6.7e-40 137.5 0.1 1e-37 130.3 0.1 2.4 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 KXH39557.1 - 8.9e-22 77.4 0.0 2.3e-21 76.0 0.0 1.7 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Proteasome PF00227.26 KXH39558.1 - 2.8e-28 98.7 0.4 9.7e-28 96.9 0.2 1.9 2 1 0 2 2 2 1 Proteasome subunit YTH PF04146.15 KXH39559.1 - 1e-62 211.0 0.0 1.8e-62 210.2 0.0 1.4 1 0 0 1 1 1 1 YT521-B-like domain RRM_1 PF00076.22 KXH39559.1 - 0.0033 17.2 0.0 0.01 15.7 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KXH39559.1 - 0.12 12.3 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Occluded RNA-recognition motif HSP20 PF00011.21 KXH39560.1 - 2.2e-15 56.6 0.0 1.7e-10 41.0 0.0 2.3 2 0 0 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KXH39560.1 - 6.4e-06 25.6 0.0 0.0086 15.6 0.0 2.3 2 0 0 2 2 2 2 HSP20-like domain found in ArsA SecG PF03840.14 KXH39560.1 - 0.21 11.7 0.7 0.35 11.0 0.7 1.3 1 0 0 1 1 1 0 Preprotein translocase SecG subunit Pneumo_att_G PF05539.11 KXH39560.1 - 0.49 9.9 7.8 0.64 9.6 7.8 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Rad51 PF08423.11 KXH39561.1 - 1.3e-127 424.4 0.0 1.6e-127 424.1 0.0 1.1 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 KXH39561.1 - 5.5e-09 35.9 0.0 7.6e-09 35.4 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.6 KXH39561.1 - 1.7e-08 34.3 0.0 2.6e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.6 KXH39561.1 - 4e-07 30.6 0.3 4.8e-06 27.1 0.1 2.4 2 0 0 2 2 2 1 Helix-hairpin-helix domain ATPase PF06745.13 KXH39561.1 - 1.1e-05 24.9 0.0 2.4e-05 23.8 0.0 1.6 1 1 0 1 1 1 1 KaiC DnaB_C PF03796.15 KXH39561.1 - 0.033 13.5 0.1 0.16 11.3 0.0 1.9 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain ssDNA_TraI_N PF18272.1 KXH39561.1 - 0.11 12.5 0.1 0.59 10.2 0.1 2.1 2 0 0 2 2 2 0 single-stranded DNA binding TraI N-terminal subdomain AAA_24 PF13479.6 KXH39561.1 - 0.13 11.9 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain PAXNEB PF05625.11 KXH39561.1 - 0.19 10.8 0.2 0.84 8.7 0.1 1.8 2 0 0 2 2 2 0 PAXNEB protein Nup160 PF11715.8 KXH39562.1 - 1.1e-146 489.6 0.8 1.4e-146 489.3 0.8 1.1 1 0 0 1 1 1 1 Nucleoporin Nup120/160 TPR_2 PF07719.17 KXH39562.1 - 0.33 11.2 1.5 0.69 10.2 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Peptidase_C65 PF10275.9 KXH39565.1 - 8.4e-66 221.9 0.0 1.3e-65 221.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase C65 Otubain DUF3439 PF11921.8 KXH39565.1 - 0.0081 16.1 2.5 0.024 14.6 2.5 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) PCI PF01399.27 KXH39567.1 - 1.6e-19 70.4 0.4 4.5e-19 68.9 0.0 2.0 2 0 0 2 2 2 1 PCI domain TPR_12 PF13424.6 KXH39567.1 - 0.065 13.5 0.3 6.6 7.1 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 KXH39567.1 - 0.072 13.2 4.2 0.42 10.9 0.2 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 KXH39567.1 - 0.14 12.0 1.8 1.3 9.0 0.2 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat CWC25 PF12542.8 KXH39568.1 - 1.2e-23 83.9 0.3 1.2e-23 83.9 0.3 4.2 2 2 1 3 3 3 1 Pre-mRNA splicing factor Cir_N PF10197.9 KXH39568.1 - 1.5e-13 50.6 7.3 1.5e-13 50.6 7.3 4.1 4 1 1 5 5 5 1 N-terminal domain of CBF1 interacting co-repressor CIR Whi5 PF08528.11 KXH39656.1 - 9.2e-09 34.7 0.1 1.5e-08 34.1 0.1 1.4 1 0 0 1 1 1 1 Whi5 like KIX_2 PF16987.5 KXH39657.1 - 2.1e-05 24.4 0.2 0.00016 21.6 0.2 2.7 1 0 0 1 1 1 1 KIX domain GLEYA PF10528.9 KXH39657.1 - 1.3 9.5 3.4 2.3 8.7 0.1 2.6 2 0 0 2 2 2 0 GLEYA domain FAR1 PF03101.15 KXH39659.1 - 1.9e-08 34.9 0.9 2.8e-08 34.3 0.3 1.5 2 0 0 2 2 2 1 FAR1 DNA-binding domain DnaJ PF00226.31 KXH39660.1 - 1.3e-21 76.4 1.0 5.1e-21 74.6 1.0 2.1 1 0 0 1 1 1 1 DnaJ domain DUF4552 PF15089.6 KXH39662.1 - 1.2 8.1 5.8 1.4 7.9 5.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4552) Metallophos PF00149.28 KXH39663.1 - 1.4e-09 38.8 0.0 2.7e-09 37.8 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KXH39663.1 - 0.0071 16.5 0.0 1.9 8.7 0.0 2.4 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.6 KXH39663.1 - 0.22 10.8 0.0 0.5 9.7 0.0 1.5 2 0 0 2 2 2 0 Metallophosphoesterase, calcineurin superfamily PAS_9 PF13426.7 KXH39693.1 - 2e-24 85.8 0.0 2.4e-16 59.9 0.0 3.6 3 0 0 3 3 3 3 PAS domain PAS_3 PF08447.12 KXH39693.1 - 4.6e-20 71.7 0.0 8.8e-12 45.2 0.0 3.7 3 0 0 3 3 3 3 PAS fold PAS PF00989.25 KXH39693.1 - 6.9e-16 58.3 0.0 9.2e-07 28.9 0.0 4.0 3 1 0 3 3 3 3 PAS fold GATA PF00320.27 KXH39693.1 - 2.5e-15 55.8 7.4 5.8e-15 54.6 7.4 1.6 1 0 0 1 1 1 1 GATA zinc finger PAS_4 PF08448.10 KXH39693.1 - 3.7e-09 36.8 0.0 0.0081 16.4 0.0 3.5 3 0 0 3 3 3 2 PAS fold PAS_11 PF14598.6 KXH39693.1 - 6.5e-07 29.5 0.0 0.0055 16.8 0.0 2.8 2 0 0 2 2 2 2 PAS domain PAS_2 PF08446.11 KXH39693.1 - 3.6e-05 24.4 0.0 0.12 13.0 0.0 3.5 3 0 0 3 3 3 1 PAS fold RTA1 PF04479.13 KXH39694.1 - 3e-42 144.6 5.3 3.8e-42 144.2 5.3 1.1 1 0 0 1 1 1 1 RTA1 like protein DUF4501 PF14946.6 KXH39694.1 - 0.31 11.1 3.4 1.1 9.3 0.1 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4501) Inp1 PF12634.7 KXH39695.1 - 1.9e-35 121.9 0.0 5.8e-35 120.3 0.0 1.9 1 0 0 1 1 1 1 Inheritance of peroxisomes protein 1 EI24 PF07264.11 KXH39696.1 - 6.4e-17 62.4 5.3 2.7e-08 34.2 0.3 2.2 1 1 1 2 2 2 2 Etoposide-induced protein 2.4 (EI24) Lumazine_bd_2 PF12893.7 KXH39696.1 - 0.078 13.7 0.1 0.2 12.3 0.1 1.7 1 0 0 1 1 1 0 Putative lumazine-binding FmdA_AmdA PF03069.15 KXH39697.1 - 7.5e-179 594.4 0.0 8.7e-179 594.1 0.0 1.0 1 0 0 1 1 1 1 Acetamidase/Formamidase family OTU PF02338.19 KXH39698.1 - 5.8e-10 39.8 0.0 9.3e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease Bromodomain PF00439.25 KXH39699.1 - 8.3e-39 131.5 1.9 7.8e-19 67.5 0.1 2.6 2 0 0 2 2 2 2 Bromodomain BAH PF01426.18 KXH39699.1 - 5e-17 61.9 0.5 1.8e-16 60.1 0.5 2.0 1 0 0 1 1 1 1 BAH domain CDC45 PF02724.14 KXH39699.1 - 0.0016 16.8 9.9 0.0016 16.8 9.9 3.1 3 0 0 3 3 3 1 CDC45-like protein Ribosomal_60s PF00428.19 KXH39699.1 - 0.008 16.7 8.6 0.008 16.7 8.6 5.2 3 1 0 3 3 3 1 60s Acidic ribosomal protein DUF913 PF06025.12 KXH39699.1 - 0.017 14.1 0.4 0.017 14.1 0.4 3.0 3 0 0 3 3 3 0 Domain of Unknown Function (DUF913) Zip PF02535.22 KXH39699.1 - 6.5 5.9 4.7 1.3 8.1 0.3 2.1 2 0 0 2 2 2 0 ZIP Zinc transporter Gly-rich_Ago1 PF12764.7 KXH39700.1 - 0.073 13.9 0.1 0.073 13.9 0.1 3.4 3 0 0 3 3 3 0 Glycine-rich region of argonaut adh_short PF00106.25 KXH39701.1 - 7.6e-40 136.5 1.4 9.5e-40 136.1 1.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXH39701.1 - 1e-38 133.2 1.4 1.2e-38 133.1 1.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH39701.1 - 2.9e-07 30.6 0.4 3.9e-07 30.2 0.4 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXH39701.1 - 0.0021 17.6 0.8 0.034 13.6 0.8 2.5 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family Thymidylate_kin PF02223.17 KXH39706.1 - 2e-45 154.7 0.0 2.1e-44 151.4 0.0 1.9 2 0 0 2 2 2 1 Thymidylate kinase AAA_28 PF13521.6 KXH39706.1 - 0.00036 20.8 0.0 0.00076 19.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.10 KXH39706.1 - 0.064 12.7 0.0 0.1 12.0 0.0 1.4 1 1 0 1 1 1 0 Chromatin associated protein KTI12 Peptidase_M1_N PF17900.1 KXH39707.1 - 0.078 13.2 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 Peptidase M1 N-terminal domain MF_alpha_N PF05436.11 KXH39709.1 - 0.16 11.9 0.1 0.2 11.6 0.1 1.1 1 0 0 1 1 1 0 Mating factor alpha precursor N-terminus DUF3328 PF11807.8 KXH39710.1 - 2.2e-50 171.5 0.4 2.7e-50 171.2 0.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) adh_short PF00106.25 KXH39711.1 - 5.6e-22 78.2 0.0 5.6e-18 65.1 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXH39711.1 - 5.8e-15 55.5 0.0 3.3e-14 53.0 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH39711.1 - 0.00019 21.4 0.0 0.00027 20.9 0.0 1.2 1 0 0 1 1 1 1 KR domain Acyl_transf_3 PF01757.22 KXH39712.1 - 3.6e-30 105.2 38.7 3.8e-30 105.1 35.1 2.3 2 1 0 2 2 2 1 Acyltransferase family OpgC_C PF10129.9 KXH39712.1 - 0.001 18.0 6.2 0.025 13.5 0.1 2.5 1 1 1 2 2 2 2 OpgC protein CReP_N PF10472.9 KXH39712.1 - 0.025 13.5 0.1 0.046 12.6 0.1 1.3 1 0 0 1 1 1 0 eIF2-alpha phosphatase phosphorylation constitutive repressor An_peroxidase PF03098.15 KXH39714.1 - 6.9e-36 123.9 0.0 1.3e-24 86.7 0.0 4.0 1 1 1 2 2 2 2 Animal haem peroxidase p450 PF00067.22 KXH39714.1 - 3.4e-08 32.7 0.0 2.7e-06 26.4 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 PMI_typeI PF01238.21 KXH39715.1 - 5.3e-138 460.3 0.0 6.1e-138 460.1 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I DUF1325 PF07039.11 KXH39716.1 - 2.6e-34 118.2 0.0 3.9e-34 117.6 0.0 1.3 1 0 0 1 1 1 1 SGF29 tudor-like domain Tudor_3 PF18115.1 KXH39716.1 - 0.036 13.9 0.0 0.11 12.4 0.0 1.8 2 0 0 2 2 2 0 DNA repair protein Crb2 Tudor domain Arf PF00025.21 KXH39717.1 - 6e-75 250.5 0.1 6.9e-75 250.3 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KXH39717.1 - 4.1e-14 52.8 0.0 5.7e-14 52.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KXH39717.1 - 2e-12 47.0 0.0 2.2e-12 46.9 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 KXH39717.1 - 6.5e-12 45.3 2.1 4.6e-08 32.6 0.3 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 KXH39717.1 - 1.1e-11 44.4 0.0 1.4e-11 44.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KXH39717.1 - 1e-10 41.3 0.0 1.3e-10 41.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KXH39717.1 - 0.00051 20.1 0.0 0.00067 19.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 KXH39717.1 - 0.057 12.7 0.1 0.094 12.0 0.1 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase CRISPR_Cas2 PF09827.9 KXH39717.1 - 0.08 13.1 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 CRISPR associated protein Cas2 SPX PF03105.19 KXH39718.1 - 6.9 6.5 7.8 8.5 6.2 7.8 1.1 1 0 0 1 1 1 0 SPX domain ABC_tran PF00005.27 KXH39719.1 - 1.2e-42 145.6 0.1 7.3e-20 71.9 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KXH39719.1 - 1.4e-31 110.1 28.2 6.6e-26 91.6 12.0 2.5 3 0 0 3 3 2 2 ABC transporter transmembrane region SMC_N PF02463.19 KXH39719.1 - 1.2e-10 41.3 0.0 0.15 11.5 0.0 4.2 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KXH39719.1 - 3.2e-09 37.0 1.8 0.24 11.2 0.0 4.2 3 1 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KXH39719.1 - 3.3e-07 30.4 1.0 0.0014 18.6 0.3 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 KXH39719.1 - 1.3e-05 25.4 0.7 0.12 12.6 0.0 3.1 2 1 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 KXH39719.1 - 1.4e-05 25.2 0.1 0.07 13.2 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 KXH39719.1 - 0.00011 21.9 1.1 0.45 10.3 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain SbcCD_C PF13558.6 KXH39719.1 - 0.00012 22.2 0.5 0.4 10.9 0.0 3.2 3 0 0 3 3 2 2 Putative exonuclease SbcCD, C subunit Dynamin_N PF00350.23 KXH39719.1 - 0.00085 19.4 0.8 0.039 14.0 0.0 2.3 2 0 0 2 2 2 1 Dynamin family DUF815 PF05673.13 KXH39719.1 - 0.0029 16.8 0.1 0.1 11.7 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) NB-ARC PF00931.22 KXH39719.1 - 0.0034 16.6 0.4 0.062 12.5 0.0 2.4 2 1 0 2 2 2 1 NB-ARC domain AAA_16 PF13191.6 KXH39719.1 - 0.0041 17.5 0.5 2.8 8.3 0.1 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_15 PF13175.6 KXH39719.1 - 0.0082 15.9 0.5 0.42 10.3 0.1 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_7 PF12775.7 KXH39719.1 - 0.034 13.7 0.3 2.3 7.7 0.1 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_23 PF13476.6 KXH39719.1 - 0.039 14.5 0.3 9.2 6.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KXH39719.1 - 0.041 13.8 0.2 5.4 6.9 0.0 2.5 2 0 0 2 2 2 0 NACHT domain AAA PF00004.29 KXH39719.1 - 0.051 14.0 0.0 0.47 10.9 0.0 2.7 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) Roc PF08477.13 KXH39719.1 - 0.089 13.0 0.5 18 5.6 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Viral_helicase1 PF01443.18 KXH39719.1 - 0.23 11.2 0.2 9.5 5.9 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Rad17 PF03215.15 KXH39719.1 - 0.35 10.8 1.9 0.81 9.6 0.3 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain cobW PF02492.19 KXH39719.1 - 0.78 9.3 2.9 21 4.6 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.14 KXH39719.1 - 0.83 9.6 3.3 19 5.3 0.1 3.2 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) TsaE PF02367.17 KXH39719.1 - 1.9 8.5 3.2 2.5 8.1 0.2 2.7 4 0 0 4 4 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Not3 PF04065.15 KXH39720.1 - 0.018 14.5 0.1 0.025 14.0 0.1 1.2 1 0 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component ZapA PF05164.13 KXH39720.1 - 0.053 14.0 1.1 0.12 12.8 1.0 1.7 1 1 0 1 1 1 0 Cell division protein ZapA Lipase_GDSL_2 PF13472.6 KXH39721.1 - 1.1e-10 42.3 1.0 2.3e-10 41.2 1.0 1.6 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KXH39721.1 - 3.5e-10 40.2 1.6 7.3e-10 39.2 1.6 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase CE2_N PF17996.1 KXH39721.1 - 0.09 12.8 0.1 0.21 11.6 0.1 1.6 1 0 0 1 1 1 0 Carbohydrate esterase 2 N-terminal Glyco_transf_90 PF05686.12 KXH39794.1 - 6.2e-22 78.0 0.0 2.9e-17 62.7 0.0 2.1 2 0 0 2 2 2 2 Glycosyl transferase family 90 Glyco_hydro_72 PF03198.14 KXH39795.1 - 3.6e-126 420.7 5.1 4.6e-126 420.3 5.1 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 KXH39795.1 - 1.5e-05 24.6 1.1 0.00019 21.0 1.1 2.2 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) FCH PF00611.23 KXH39796.1 - 7.6e-26 90.2 1.9 1.1e-25 89.7 0.1 2.3 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.6 KXH39796.1 - 6.7e-19 67.5 0.6 2.1e-12 46.7 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain C1_1 PF00130.22 KXH39796.1 - 2e-15 56.4 5.3 3.2e-15 55.8 5.3 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_1 PF00018.28 KXH39796.1 - 4e-12 45.6 0.1 3.2e-05 23.4 0.0 2.4 2 0 0 2 2 2 2 SH3 domain SH3_10 PF17902.1 KXH39796.1 - 0.001 19.1 0.0 0.14 12.3 0.0 3.2 3 0 0 3 3 3 1 SH3 domain SH3_3 PF08239.11 KXH39796.1 - 0.0028 17.9 0.6 0.3 11.4 0.2 2.5 2 0 0 2 2 2 1 Bacterial SH3 domain Allexi_40kDa PF05549.11 KXH39796.1 - 0.047 13.2 3.2 0.1 12.1 0.1 2.5 2 1 0 2 2 2 0 Allexivirus 40kDa protein C1_2 PF03107.16 KXH39796.1 - 0.053 13.9 5.5 0.092 13.1 5.5 1.4 1 0 0 1 1 1 0 C1 domain SH3_16 PF18348.1 KXH39796.1 - 0.16 11.8 0.1 3.5 7.5 0.0 2.4 2 0 0 2 2 2 0 Bacterial dipeptidyl-peptidase Sh3 domain FYVE PF01363.21 KXH39796.1 - 0.23 11.6 3.0 0.49 10.6 3.0 1.4 1 0 0 1 1 1 0 FYVE zinc finger Dor1 PF04124.12 KXH39796.1 - 0.56 8.8 5.7 0.13 11.0 2.0 1.7 2 0 0 2 2 2 0 Dor1-like family DEAD PF00270.29 KXH39797.1 - 7e-34 117.1 0.0 1.5e-33 116.0 0.0 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXH39797.1 - 2.6e-24 85.7 0.0 5.7e-24 84.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 KXH39797.1 - 0.00018 21.3 0.0 0.00033 20.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 KXH39797.1 - 0.00021 21.4 0.0 0.00041 20.4 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KXH39797.1 - 0.049 14.0 0.0 0.79 10.0 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KXH39797.1 - 0.092 13.0 1.1 0.48 10.7 0.7 2.3 2 1 0 2 2 2 0 AAA domain CFEM PF05730.11 KXH39798.1 - 0.021 14.9 3.6 0.04 14.0 3.6 1.4 1 0 0 1 1 1 0 CFEM domain KGG PF10685.9 KXH39799.1 - 6.7e-43 143.8 26.6 2.8e-10 40.1 1.2 5.2 5 0 0 5 5 5 5 Stress-induced bacterial acidophilic repeat motif SLX9 PF15341.6 KXH39800.1 - 3.8e-39 134.1 4.1 6.1e-39 133.4 4.1 1.3 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 DTW PF03942.15 KXH39800.1 - 0.037 13.7 0.0 0.06 13.1 0.0 1.3 1 0 0 1 1 1 0 DTW domain ThiF PF00899.21 KXH39801.1 - 4.2e-56 190.0 0.0 4.4e-55 186.7 0.0 2.0 1 1 1 2 2 2 1 ThiF family Rhodanese PF00581.20 KXH39801.1 - 8.8e-12 45.5 0.0 6.4e-11 42.7 0.0 2.1 2 0 0 2 2 2 1 Rhodanese-like domain NAD_binding_7 PF13241.6 KXH39801.1 - 0.011 16.2 0.0 0.022 15.2 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Shikimate_DH PF01488.20 KXH39801.1 - 0.015 15.3 0.9 0.055 13.5 0.1 2.3 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_N PF03721.14 KXH39801.1 - 0.1 12.1 1.2 0.22 11.1 1.2 1.7 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AlaDh_PNT_C PF01262.21 KXH39801.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Bap31_Bap29_C PF18035.1 KXH39801.1 - 2 8.5 5.8 1.5 8.9 3.4 1.9 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain Pam17 PF08566.10 KXH39802.1 - 2e-66 222.9 0.0 2.9e-66 222.4 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 Med3 PF11593.8 KXH39802.1 - 0.042 13.1 3.6 0.046 12.9 3.6 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Chromo PF00385.24 KXH39803.1 - 2.3e-07 30.6 0.0 1.4e-05 24.9 0.0 2.6 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Ribosomal_60s PF00428.19 KXH39803.1 - 0.0015 19.1 14.6 0.0015 19.1 14.6 4.2 4 0 0 4 4 4 1 60s Acidic ribosomal protein Pox_Ag35 PF03286.14 KXH39803.1 - 1.3 8.8 19.3 0.22 11.3 8.0 3.3 3 0 0 3 3 3 0 Pox virus Ag35 surface protein DUF2052 PF09747.9 KXH39803.1 - 5.8 7.0 19.3 0.037 14.2 4.4 2.6 2 1 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) AIG2_2 PF13772.6 KXH39804.1 - 5.8e-05 23.4 0.0 0.00023 21.5 0.0 2.0 2 0 0 2 2 2 1 AIG2-like family NAD_Gly3P_dh_N PF01210.23 KXH39805.1 - 1.1e-45 155.4 0.0 7.7e-45 152.7 0.0 2.0 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 KXH39805.1 - 6.4e-42 143.2 0.1 1.1e-41 142.4 0.1 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus HABP4_PAI-RBP1 PF04774.15 KXH39805.1 - 0.11 13.3 0.0 0.22 12.4 0.0 1.5 1 0 0 1 1 1 0 Hyaluronan / mRNA binding family DUF3605 PF12239.8 KXH39811.1 - 5.7e-57 192.3 0.2 6.8e-57 192.1 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) FolB PF02152.18 KXH39812.1 - 1.7e-21 76.8 0.0 1.8e-14 54.2 0.0 2.2 2 0 0 2 2 2 2 Dihydroneopterin aldolase ERAP1_C PF11838.8 KXH39813.1 - 4.6e-87 292.5 1.1 1.2e-86 291.1 0.8 1.8 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 KXH39813.1 - 3.5e-83 278.5 0.1 5.5e-83 277.8 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 KXH39813.1 - 5.5e-57 193.0 0.1 5.5e-56 189.7 0.0 2.2 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain Enolase_C PF00113.22 KXH39814.1 - 3.3e-152 505.9 0.2 4.3e-152 505.5 0.2 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 KXH39814.1 - 1.5e-58 196.6 0.2 2.9e-58 195.7 0.2 1.5 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 KXH39814.1 - 9.8e-06 25.3 0.1 1.9e-05 24.3 0.1 1.4 1 1 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 KXH39814.1 - 0.048 12.8 0.3 0.67 9.1 0.1 2.4 3 0 0 3 3 3 0 Methylaspartate ammonia-lyase C-terminus PKD_channel PF08016.12 KXH39815.1 - 0.00015 20.6 3.5 0.056 12.1 0.3 2.2 2 0 0 2 2 2 2 Polycystin cation channel Sm_multidrug_ex PF06695.11 KXH39815.1 - 1.8 9.2 6.2 0.42 11.2 2.0 2.1 2 0 0 2 2 2 0 Putative small multi-drug export protein Glyco_hydro_67M PF07488.12 KXH39816.1 - 5.1e-140 466.1 0.0 7.9e-140 465.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 middle domain Glyco_hydro_67C PF07477.12 KXH39816.1 - 1.9e-89 299.1 1.5 2.7e-89 298.5 1.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 C-terminus Glyco_hydro_67N PF03648.14 KXH39816.1 - 7e-26 90.9 0.0 1.5e-25 89.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 N-terminus Glyco_hydro_20b PF02838.15 KXH39816.1 - 0.0046 17.7 0.1 0.015 16.1 0.1 1.8 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Ribul_P_3_epim PF00834.19 KXH39816.1 - 0.15 11.5 0.0 0.34 10.3 0.0 1.5 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family FliD_N PF02465.18 KXH39816.1 - 0.22 12.2 0.7 0.42 11.3 0.7 1.4 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus MTS PF05175.14 KXH39817.1 - 0.014 15.0 0.0 0.036 13.6 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase small domain LSM PF01423.22 KXH39818.1 - 8.4e-18 63.8 0.1 1.1e-17 63.5 0.1 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KXH39818.1 - 0.0067 16.5 0.0 0.01 15.9 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain Tyrosinase PF00264.20 KXH39819.1 - 4.1e-48 164.6 3.9 7.2e-48 163.8 3.9 1.4 1 0 0 1 1 1 1 Common central domain of tyrosinase Tyosinase_C PF18132.1 KXH39819.1 - 2.7e-33 115.2 0.0 4.4e-33 114.5 0.0 1.4 1 0 0 1 1 1 1 Tyosinase C-terminal domain RNA_pol_Rpb2_6 PF00562.28 KXH39820.1 - 1.1e-111 373.7 0.0 1.5e-111 373.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 KXH39820.1 - 2e-32 112.4 0.0 3e-32 111.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 KXH39820.1 - 8.1e-29 99.6 0.2 2.4e-28 98.1 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_2 PF04561.14 KXH39820.1 - 2e-26 92.8 0.0 3.1e-26 92.2 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpa2_4 PF06883.12 KXH39820.1 - 1.1e-23 83.0 0.0 2.3e-23 82.0 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_7 PF04560.20 KXH39820.1 - 5.4e-16 58.8 0.0 1.8e-14 53.9 0.0 2.5 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 7 zinc_ribbon_15 PF17032.5 KXH39820.1 - 0.14 12.9 0.1 0.32 11.8 0.1 1.5 1 0 0 1 1 1 0 zinc-ribbon family Glyco_hydro_16 PF00722.21 KXH39908.1 - 1e-16 60.9 0.0 1.7e-16 60.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Glyco_hydro_64 PF16483.5 KXH39909.1 - 3.4e-140 467.5 0.3 4.2e-140 467.2 0.3 1.1 1 0 0 1 1 1 1 Beta-1,3-glucanase Fungal_trans_2 PF11951.8 KXH39910.1 - 1.6e-12 47.0 0.2 1.7e-09 37.0 0.0 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Pro_isomerase PF00160.21 KXH39911.1 - 2.5e-49 167.6 0.0 4.7e-49 166.7 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD U-box PF04564.15 KXH39911.1 - 0.00017 21.7 0.0 0.0006 19.9 0.0 1.9 1 0 0 1 1 1 1 U-box domain zf-NOSIP PF15906.5 KXH39911.1 - 0.00077 19.6 0.0 0.002 18.2 0.0 1.7 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein Lung_7-TM_R PF06814.13 KXH39912.1 - 8.1e-71 238.7 16.3 1e-70 238.3 16.3 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor SurA_N_3 PF13624.6 KXH39912.1 - 0.61 9.8 2.0 9.4 6.0 0.3 2.6 2 0 0 2 2 2 0 SurA N-terminal domain DUF1980 PF09323.10 KXH39912.1 - 0.89 9.4 4.4 0.39 10.6 0.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF1980) DUF4492 PF14899.6 KXH39912.1 - 1.4 8.9 5.6 0.65 9.9 1.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4492) Methyltransf_28 PF02636.17 KXH39913.1 - 1.1e-81 274.4 0.0 1.3e-81 274.1 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Pkinase PF00069.25 KXH39914.1 - 1.4e-59 201.6 0.0 2.3e-59 200.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXH39914.1 - 1.8e-25 89.7 0.0 1.5e-23 83.5 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXH39914.1 - 0.0013 18.1 0.0 0.0023 17.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KXH39914.1 - 0.03 14.2 0.0 0.03 14.2 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family LpxI_C PF06230.11 KXH39914.1 - 0.14 12.0 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 LpxI C-terminal domain Haspin_kinase PF12330.8 KXH39914.1 - 0.21 10.5 0.0 0.28 10.1 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 KXH39914.1 - 0.86 8.3 3.1 2.2 7.0 3.1 1.6 1 1 0 1 1 1 0 Fungal protein kinase SOG2 PF10428.9 KXH39915.1 - 0.029 13.6 1.8 0.037 13.3 1.8 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DUF3617 PF12276.8 KXH39915.1 - 0.081 13.2 0.0 0.081 13.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3617) DmpG_comm PF07836.11 KXH39915.1 - 0.12 12.0 0.1 0.23 11.0 0.1 1.4 1 0 0 1 1 1 0 DmpG-like communication domain BolA PF01722.18 KXH39916.1 - 1.8e-18 66.6 0.0 2.1e-18 66.4 0.0 1.1 1 0 0 1 1 1 1 BolA-like protein zf-C2H2_11 PF16622.5 KXH39916.1 - 0.059 13.1 0.2 5.5 6.9 0.0 2.3 2 0 0 2 2 2 0 zinc-finger C2H2-type Adaptin_N PF01602.20 KXH39917.1 - 2.1e-138 462.2 1.6 3e-138 461.7 1.6 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KXH39917.1 - 6.7e-63 211.6 1.2 8.9e-61 204.7 0.1 2.7 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KXH39917.1 - 5.7e-17 61.9 0.1 2.3e-07 31.1 0.0 5.2 2 2 5 7 7 7 4 HEAT repeats HEAT PF02985.22 KXH39917.1 - 5.2e-11 41.8 4.4 0.023 14.9 0.0 6.4 8 0 0 8 8 8 2 HEAT repeat HEAT_EZ PF13513.6 KXH39917.1 - 0.00014 22.3 0.1 0.64 10.6 0.0 4.7 3 1 1 4 4 4 1 HEAT-like repeat UNC45-central PF11701.8 KXH39917.1 - 0.0043 17.0 0.1 0.25 11.3 0.0 2.7 2 0 0 2 2 2 1 Myosin-binding striated muscle assembly central RIX1 PF08167.12 KXH39917.1 - 0.0098 15.7 0.1 3.5 7.3 0.0 2.9 3 0 0 3 3 3 1 rRNA processing/ribosome biogenesis Atx10homo_assoc PF09759.9 KXH39917.1 - 0.011 15.8 0.0 1.8 8.7 0.0 3.5 2 1 1 3 3 3 0 Spinocerebellar ataxia type 10 protein domain Arm PF00514.23 KXH39917.1 - 0.015 15.3 1.4 7.6 6.7 0.0 4.9 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat CLASP_N PF12348.8 KXH39917.1 - 0.05 13.2 0.0 1.7 8.2 0.0 2.9 2 1 1 3 3 3 0 CLASP N terminal RTP1_C1 PF10363.9 KXH39917.1 - 0.22 11.7 0.8 6.9 6.9 0.0 3.6 2 2 2 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 Cupin_1 PF00190.22 KXH39918.1 - 4.8e-05 23.0 0.2 0.00082 19.0 0.5 2.1 2 0 0 2 2 2 1 Cupin Cupin_2 PF07883.11 KXH39918.1 - 0.00017 21.3 1.6 0.00051 19.7 1.2 2.0 2 1 0 2 2 2 1 Cupin domain ARD PF03079.14 KXH39918.1 - 0.081 13.1 0.1 0.14 12.3 0.1 1.3 1 0 0 1 1 1 0 ARD/ARD' family DNA_ligase_A_M PF01068.21 KXH39919.1 - 4.1e-49 167.0 0.2 1.9e-46 158.3 0.0 2.2 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KXH39919.1 - 8.2e-35 120.7 0.0 1.7e-34 119.7 0.0 1.6 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 KXH39919.1 - 7e-20 71.5 0.1 3e-19 69.4 0.0 2.2 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region NuDC PF16273.5 KXH39919.1 - 0.012 16.1 2.9 0.012 16.1 2.9 2.1 2 0 0 2 2 2 0 Nuclear distribution C domain mRNA_cap_enzyme PF01331.19 KXH39919.1 - 0.097 12.5 0.0 1.7 8.4 0.0 2.1 2 0 0 2 2 2 0 mRNA capping enzyme, catalytic domain CSN8_PSD8_EIF3K PF10075.9 KXH39920.1 - 1.3e-39 135.4 0.0 1.8e-39 135.0 0.0 1.2 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family PDCD2_C PF04194.13 KXH39921.1 - 3.1e-42 144.6 0.0 3.1e-42 144.6 0.0 3.2 3 1 1 4 4 4 1 Programmed cell death protein 2, C-terminal putative domain Ribosomal_60s PF00428.19 KXH39921.1 - 0.014 16.0 2.4 0.014 16.0 2.4 2.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein Zn_ribbon_recom PF13408.6 KXH39921.1 - 0.79 10.3 3.1 3.5 8.2 0.2 2.3 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain Cpn60_TCP1 PF00118.24 KXH39922.1 - 3e-163 544.0 1.3 3.4e-163 543.8 1.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Herpes_UL6 PF01763.16 KXH39922.1 - 0.12 10.9 0.0 0.17 10.4 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like Prenylcys_lyase PF07156.14 KXH39923.1 - 8.1e-112 373.9 0.0 1.1e-111 373.5 0.0 1.1 1 0 0 1 1 1 1 Prenylcysteine lyase Amino_oxidase PF01593.24 KXH39923.1 - 2.9e-13 49.9 0.0 4.1e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KXH39923.1 - 4.5e-12 46.0 0.1 1.3e-11 44.5 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXH39923.1 - 3.2e-06 27.0 0.1 0.00015 21.5 0.2 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXH39923.1 - 8e-05 22.0 0.1 0.008 15.4 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXH39923.1 - 0.0068 16.4 0.1 0.044 13.8 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.17 KXH39923.1 - 0.032 13.5 0.1 0.072 12.3 0.1 1.5 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.27 KXH39923.1 - 0.039 14.5 0.1 1.2 9.7 0.1 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase MCRA PF06100.11 KXH39923.1 - 0.042 12.6 0.4 0.12 11.1 0.0 1.9 3 0 0 3 3 3 0 MCRA family VID27 PF08553.10 KXH39924.1 - 1.7e-193 642.5 0.1 2.2e-193 642.1 0.1 1.1 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain VID27_N PF17748.1 KXH39924.1 - 1.7e-77 259.1 0.3 1.7e-77 259.1 0.3 2.8 2 1 0 2 2 2 1 VID27 N-terminal region VID27_PH PF17747.1 KXH39924.1 - 8e-44 148.4 1.1 1.7e-43 147.4 0.6 1.8 2 0 0 2 2 2 1 VID27 PH-like domain DNA_pol_phi PF04931.13 KXH39924.1 - 0.15 10.2 13.8 0.23 9.5 13.8 1.2 1 0 0 1 1 1 0 DNA polymerase phi Herpes_gE PF02480.16 KXH39924.1 - 0.51 9.0 4.7 0.84 8.3 4.7 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E CDC45 PF02724.14 KXH39924.1 - 1.5 7.0 7.8 2.1 6.5 7.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Astro_capsid_p PF12226.8 KXH39924.1 - 2 7.5 19.1 3.6 6.7 19.1 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Nop14 PF04147.12 KXH39924.1 - 3 5.9 14.3 4.8 5.3 14.3 1.2 1 0 0 1 1 1 0 Nop14-like family Pox_Ag35 PF03286.14 KXH39924.1 - 4.6 7.0 18.2 0.53 10.1 0.6 2.3 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Glyco_transf_20 PF00982.21 KXH39925.1 - 8.7e-199 661.1 0.0 1e-198 660.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glyco_transf_5 PF08323.11 KXH39925.1 - 0.03 14.0 0.1 0.1 12.3 0.0 1.9 2 0 0 2 2 2 0 Starch synthase catalytic domain Med28 PF11594.8 KXH39925.1 - 0.12 12.4 0.1 0.79 9.8 0.1 2.1 2 0 0 2 2 2 0 Mediator complex subunit 28 Aldose_epim PF01263.20 KXH39927.1 - 1.9e-54 185.1 0.0 2.3e-54 184.7 0.0 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase zf-met2 PF12907.7 KXH39927.1 - 0.017 15.2 0.4 0.039 14.1 0.4 1.6 1 0 0 1 1 1 0 Zinc-binding DUF3767 PF12597.8 KXH39929.1 - 1.8e-37 127.2 0.0 1.8e-37 127.2 0.0 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF3767) 5TM-5TMR_LYT PF07694.12 KXH39929.1 - 0.0011 18.5 0.2 0.0014 18.2 0.2 1.1 1 0 0 1 1 1 1 5TMR of 5TMR-LYT LapA_dom PF06305.11 KXH39929.1 - 2.1 8.2 5.3 26 4.7 5.3 2.1 1 1 0 1 1 1 0 Lipopolysaccharide assembly protein A domain DUF1744 PF08490.12 KXH39930.1 - 4.4e-156 519.5 0.0 6.7e-156 518.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.19 KXH39930.1 - 2e-79 267.2 0.5 4.4e-79 266.1 0.2 1.7 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 KXH39930.1 - 2.2e-14 53.0 1.8 8.9e-13 47.7 1.3 3.1 2 1 0 2 2 2 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 KXH39930.1 - 1.2e-08 34.9 0.2 3.4e-08 33.4 0.2 1.7 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 KXH39930.1 - 1.3e-05 25.3 0.1 8.2e-05 22.7 0.0 2.4 2 0 0 2 2 2 1 RNase_H superfamily Peptidase_S8 PF00082.22 KXH39932.1 - 5.4e-09 35.7 0.0 1.2e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Subtilase family NPP1 PF05630.11 KXH39934.1 - 6.1e-49 166.8 0.0 7.2e-49 166.6 0.0 1.1 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) MFS_1 PF07690.16 KXH39935.1 - 1.5e-50 172.1 26.9 1.5e-50 172.1 26.9 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH39935.1 - 1.2e-16 60.7 5.5 1.2e-16 60.7 5.5 2.0 1 1 1 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KXH39935.1 - 0.00027 19.5 2.2 0.00052 18.6 2.2 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 KXH39935.1 - 0.0015 16.9 1.2 0.0015 16.9 1.2 2.5 2 1 1 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family MFS_3 PF05977.13 KXH39935.1 - 0.0023 16.4 1.6 0.003 16.0 1.6 1.2 1 0 0 1 1 1 1 Transmembrane secretion effector DUF2897 PF11446.8 KXH39935.1 - 0.57 10.1 1.7 1.1 9.2 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2897) Fungal_trans_2 PF11951.8 KXH39936.1 - 8.8e-06 24.8 0.0 1.5e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH39936.1 - 0.0077 16.3 1.9 0.015 15.4 1.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain YebG PF07130.12 KXH39936.1 - 0.017 14.9 0.2 0.044 13.6 0.2 1.6 1 0 0 1 1 1 0 YebG protein RTA1 PF04479.13 KXH39937.1 - 6.7e-70 234.9 10.6 6.7e-70 234.9 10.6 1.4 2 0 0 2 2 2 1 RTA1 like protein TRAP_alpha PF03896.16 KXH39937.1 - 0.00065 19.0 0.0 0.0012 18.2 0.0 1.3 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit Tetraspanin PF00335.20 KXH39937.1 - 3.3 7.3 10.8 0.25 11.0 1.5 2.4 2 1 0 2 2 2 0 Tetraspanin family FAD_binding_4 PF01565.23 KXH39938.1 - 3.4e-21 75.4 0.1 5.7e-21 74.7 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KXH39938.1 - 0.049 13.7 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Berberine and berberine like Glyco_hydro_3_C PF01915.22 KXH39939.1 - 1.4e-49 168.9 0.0 2.9e-49 167.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KXH39939.1 - 3.6e-41 141.6 0.0 6.7e-41 140.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KXH39939.1 - 2.3e-25 88.5 0.3 5.4e-25 87.3 0.1 1.8 2 0 0 2 2 2 1 Fibronectin type III-like domain p450 PF00067.22 KXH39939.1 - 2.1e-14 53.1 0.0 2.8e-14 52.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 TipAS PF07739.13 KXH39940.1 - 0.04 14.5 0.6 0.04 14.5 0.6 1.9 1 1 1 2 2 2 0 TipAS antibiotic-recognition domain Phasin PF05597.11 KXH39940.1 - 0.051 13.6 15.4 0.25 11.4 4.9 2.1 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) C1_2 PF03107.16 KXH39999.1 - 0.04 14.2 8.6 0.068 13.5 8.6 1.3 1 0 0 1 1 1 0 C1 domain zf-HIT PF04438.16 KXH39999.1 - 0.65 9.9 8.7 1.1 9.2 8.7 1.3 1 0 0 1 1 1 0 HIT zinc finger Alpha_GJ PF03229.13 KXH40001.1 - 0.06 13.9 2.2 0.081 13.5 2.2 1.2 1 0 0 1 1 1 0 Alphavirus glycoprotein J Glucosamine_iso PF01182.20 KXH40003.1 - 1.2e-67 228.1 0.0 1.3e-67 228.0 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase SET PF00856.28 KXH40004.1 - 9.5e-08 32.6 0.0 3e-07 31.0 0.0 1.9 1 1 0 1 1 1 1 SET domain preATP-grasp_3 PF18301.1 KXH40004.1 - 0.038 14.3 0.0 0.15 12.3 0.0 2.0 1 0 0 1 1 1 0 pre ATP-grasp 3 domain zf-MYND PF01753.18 KXH40004.1 - 0.88 9.7 12.8 0.098 12.8 6.9 2.5 2 0 0 2 2 2 0 MYND finger DUF4620 PF15399.6 KXH40005.1 - 0.085 13.2 2.7 0.09 13.1 2.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4620) Thioredoxin_6 PF13848.6 KXH40006.1 - 5.2e-11 42.8 0.0 0.00035 20.5 0.0 3.2 1 1 2 3 3 3 3 Thioredoxin-like domain Thioredoxin PF00085.20 KXH40006.1 - 6.1e-08 32.6 0.0 3.2e-06 27.1 0.0 2.5 2 0 0 2 2 2 1 Thioredoxin DUF787 PF05619.11 KXH40006.1 - 0.17 11.0 0.0 0.3 10.2 0.0 1.3 1 0 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF787) Fungal_trans PF04082.18 KXH40007.1 - 9.6e-11 41.2 2.4 1.6e-10 40.5 2.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KXH40007.1 - 1.7e-05 25.0 11.9 3.2e-05 24.1 2.5 2.7 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KXH40007.1 - 0.00019 21.7 6.7 0.0088 16.4 1.4 2.5 2 0 0 2 2 2 2 Zinc-finger double domain ERAP1_C PF11838.8 KXH40007.1 - 0.0095 15.5 1.1 0.021 14.4 0.2 1.8 2 0 0 2 2 2 1 ERAP1-like C-terminal domain zf-C2H2_4 PF13894.6 KXH40007.1 - 0.014 16.2 1.5 0.014 16.2 1.5 3.1 3 0 0 3 3 2 0 C2H2-type zinc finger PGM_PMM_IV PF00408.20 KXH40007.1 - 0.017 15.3 0.9 0.36 11.0 0.1 2.5 2 0 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, C-terminal domain SLH PF00395.20 KXH40007.1 - 0.15 12.1 0.1 0.4 10.7 0.1 1.8 1 0 0 1 1 1 0 S-layer homology domain zf-C2H2_8 PF15909.5 KXH40007.1 - 0.2 12.0 3.8 0.53 10.6 3.8 1.6 1 0 0 1 1 1 0 C2H2-type zinc ribbon zf-C2H2_11 PF16622.5 KXH40007.1 - 0.35 10.7 2.5 19 5.2 0.2 2.5 2 0 0 2 2 2 0 zinc-finger C2H2-type zinc-ribbons_6 PF07191.12 KXH40007.1 - 0.92 9.5 4.5 1.7 8.7 4.5 1.4 1 0 0 1 1 1 0 zinc-ribbons zf-LYAR PF08790.11 KXH40007.1 - 0.94 9.4 5.4 0.58 10.1 0.4 2.4 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-C2H2_6 PF13912.6 KXH40007.1 - 1.1 9.4 7.0 0.54 10.3 1.1 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger LIM PF00412.22 KXH40007.1 - 3.2 8.1 5.8 39 4.6 1.2 2.8 3 0 0 3 3 3 0 LIM domain zf-met PF12874.7 KXH40007.1 - 3.6 8.1 5.9 6.2 7.4 0.5 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type NAD_binding_2 PF03446.15 KXH40008.1 - 1.6e-12 47.9 0.1 3e-12 47.0 0.1 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KXH40008.1 - 8.3e-10 39.0 0.0 1.5e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase MFS_1 PF07690.16 KXH40009.1 - 2.5e-31 108.9 26.1 2.7e-31 108.8 25.5 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily FMO-like PF00743.19 KXH40010.1 - 1.3e-15 56.9 0.9 1.7e-13 49.8 0.6 2.7 2 2 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KXH40010.1 - 3.7e-07 30.3 0.0 8.9e-07 29.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KXH40010.1 - 4.9e-07 29.2 0.0 0.0002 20.6 0.0 3.2 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KXH40010.1 - 1.3e-05 24.6 0.0 5.3e-05 22.6 0.0 2.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXH40010.1 - 0.00036 19.9 0.0 0.17 11.1 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXH40010.1 - 0.07 13.1 0.0 2.1 8.3 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding zf-C2H2 PF00096.26 KXH40012.1 - 3.4e-07 30.3 17.9 1.8e-05 25.0 3.7 3.8 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXH40012.1 - 2.8e-05 24.6 11.8 4.4e-05 24.0 2.5 3.8 3 0 0 3 3 3 1 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KXH40012.1 - 3.4e-05 24.1 7.4 6.8e-05 23.1 4.2 2.8 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_8 PF15909.5 KXH40012.1 - 0.00019 21.7 3.9 0.00058 20.1 3.9 1.8 1 0 0 1 1 1 1 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 KXH40012.1 - 0.00065 19.9 1.1 0.00065 19.9 1.1 2.5 3 0 0 3 3 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KXH40012.1 - 0.0097 15.9 2.3 0.03 14.3 2.3 1.8 1 0 0 1 1 1 1 C2H2-type zinc finger zf-met PF12874.7 KXH40012.1 - 0.013 15.9 1.9 0.14 12.6 0.8 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.6 KXH40012.1 - 0.25 11.3 1.8 0.57 10.1 1.8 1.6 1 0 0 1 1 1 0 zinc-finger of a C2HC-type zf-C2H2_aberr PF17017.5 KXH40012.1 - 0.32 11.1 4.4 0.97 9.6 4.4 1.8 1 1 0 1 1 1 0 Aberrant zinc-finger zf-TRAF PF02176.18 KXH40012.1 - 0.4 11.4 7.7 0.094 13.4 3.3 2.0 2 0 0 2 2 2 0 TRAF-type zinc finger FOXP-CC PF16159.5 KXH40012.1 - 0.41 11.3 7.0 2.6 8.7 0.3 3.4 1 1 2 3 3 3 0 FOXP coiled-coil domain ARS2 PF04959.13 KXH40012.1 - 0.73 10.2 4.0 1.1 9.5 2.0 2.3 2 0 0 2 2 2 0 Arsenite-resistance protein 2 zf-C2HE PF16278.5 KXH40012.1 - 2.6 8.5 5.3 7.9 7.0 5.3 1.9 1 1 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_2 PF12756.7 KXH40012.1 - 7.8 6.9 8.1 3.7 7.9 3.8 2.6 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) ADH_N PF08240.12 KXH40015.1 - 6.9e-26 90.3 5.0 1.1e-25 89.6 5.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXH40015.1 - 3.7e-16 59.3 0.2 5.9e-16 58.6 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.6 KXH40015.1 - 0.052 13.4 0.2 0.08 12.8 0.2 1.3 1 0 0 1 1 1 0 NAD(P)H-binding ELFV_dehydrog PF00208.21 KXH40015.1 - 0.086 12.6 0.3 0.13 11.9 0.3 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase adh_short PF00106.25 KXH40016.1 - 2.9e-35 121.5 0.8 3.7e-35 121.2 0.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXH40016.1 - 3.4e-24 85.7 0.2 4.2e-24 85.4 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 KXH40016.1 - 0.026 13.9 0.0 0.044 13.1 0.0 1.4 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) 2-Hacid_dh_C PF02826.19 KXH40016.1 - 0.04 13.3 0.1 0.55 9.6 0.0 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NmrA PF05368.13 KXH40016.1 - 0.051 13.1 0.2 0.078 12.5 0.2 1.3 1 0 0 1 1 1 0 NmrA-like family ADH_zinc_N PF00107.26 KXH40017.1 - 1.8e-14 53.8 0.8 3.4e-14 52.9 0.1 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXH40017.1 - 2.9e-05 23.9 0.3 0.00032 20.5 0.1 2.3 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KXH40017.1 - 0.00027 22.0 0.0 0.00057 21.0 0.0 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase PD40 PF07676.12 KXH40018.1 - 6.7e-51 169.3 21.4 5.4e-07 29.4 0.0 10.4 9 1 0 9 9 9 9 WD40-like Beta Propeller Repeat DPPIV_N PF00930.21 KXH40018.1 - 3.9e-12 45.6 5.3 0.18 10.5 0.0 7.2 5 2 1 7 7 7 5 Dipeptidyl peptidase IV (DPP IV) N-terminal region WD40 PF00400.32 KXH40018.1 - 0.0015 19.3 5.0 39 5.3 0.0 7.1 6 1 0 6 6 6 0 WD domain, G-beta repeat DUF3748 PF12566.8 KXH40018.1 - 0.0042 17.0 0.7 37 4.3 0.0 4.6 4 0 0 4 4 4 0 Protein of unknown function (DUF3748) DUF5050 PF16472.5 KXH40018.1 - 0.0057 15.9 0.0 12 5.0 0.0 4.2 3 1 0 4 4 4 1 Domain of unknown function (DUF5050) TruB_C PF09142.11 KXH40018.1 - 0.016 15.0 0.0 40 4.1 0.0 4.5 6 0 0 6 6 6 0 tRNA Pseudouridine synthase II, C terminal Proteasome_A_N PF10584.9 KXH40018.1 - 0.56 9.9 14.0 1e+02 2.7 0.0 7.1 7 0 0 7 7 7 0 Proteasome subunit A N-terminal signature Stb3 PF10330.9 KXH40019.1 - 1.6e-37 127.4 0.0 2.6e-37 126.7 0.0 1.3 1 0 0 1 1 1 1 Putative Sin3 binding protein SF1-HH PF16275.5 KXH40019.1 - 0.0003 21.1 0.1 0.0008 19.7 0.1 1.6 1 0 0 1 1 1 1 Splicing factor 1 helix-hairpin domain Topoisom_bac PF01131.20 KXH40020.1 - 5.8e-109 364.8 0.0 2.5e-102 343.0 0.0 2.1 2 0 0 2 2 2 2 DNA topoisomerase Toprim PF01751.22 KXH40020.1 - 1.4e-19 70.2 0.0 3.1e-19 69.1 0.0 1.6 1 0 0 1 1 1 1 Toprim domain DUF1295 PF06966.12 KXH40021.1 - 3.8e-32 111.7 9.6 4.6e-32 111.4 9.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.14 KXH40021.1 - 0.061 13.7 3.0 0.15 12.5 0.6 2.5 2 1 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Hydrolase_6 PF13344.6 KXH40022.1 - 9.6e-27 93.1 0.0 1.6e-26 92.4 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KXH40022.1 - 2.3e-17 62.8 0.1 2.5e-16 59.5 0.0 2.4 3 0 0 3 3 3 1 HAD-hyrolase-like Hydrolase PF00702.26 KXH40022.1 - 2.4e-11 44.3 0.0 3.7e-05 24.1 0.0 2.4 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KXH40022.1 - 3.9e-05 23.8 0.0 0.076 13.1 0.0 2.2 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Malt_amylase_C PF16657.5 KXH40022.1 - 0.15 12.2 0.0 0.35 11.0 0.0 1.6 1 0 0 1 1 1 0 Maltogenic Amylase, C-terminal domain DUF4149 PF13664.6 KXH40024.1 - 1.5e-18 67.0 6.8 1.6e-18 66.9 4.2 2.3 2 1 0 2 2 2 1 Domain of unknown function (DUF4149) DUF1772 PF08592.11 KXH40024.1 - 0.0007 19.9 0.5 0.0013 19.0 0.5 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF1772) Ku_PK_bind PF08785.11 KXH40025.1 - 5.5e-34 116.9 0.0 1.2e-33 115.8 0.0 1.6 1 0 0 1 1 1 1 Ku C terminal domain like Ku PF02735.16 KXH40025.1 - 4e-30 105.1 0.0 7.2e-30 104.2 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 KXH40025.1 - 4.2e-12 46.3 0.0 7.8e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain VWA PF00092.28 KXH40025.1 - 2.1e-05 24.9 0.1 4.4e-05 23.8 0.1 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF2121 PF09894.9 KXH40025.1 - 0.033 13.7 0.0 0.068 12.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2121) Ku_C PF03730.14 KXH40025.1 - 0.064 14.0 0.0 0.23 12.2 0.0 2.0 1 0 0 1 1 1 0 Ku70/Ku80 C-terminal arm Pam16 PF03656.13 KXH40027.1 - 9.2e-07 28.9 0.0 1.1e-06 28.7 0.0 1.2 1 0 0 1 1 1 1 Pam16 DnaJ PF00226.31 KXH40027.1 - 5.5e-05 23.2 0.0 8.6e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain DUF3918 PF13056.6 KXH40027.1 - 0.04 13.5 1.1 0.096 12.3 1.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3918) Ribosomal_L24e PF01246.20 KXH40028.1 - 1.7e-31 108.2 6.2 3.7e-31 107.1 6.2 1.6 1 0 0 1 1 1 1 Ribosomal protein L24e DUF3602 PF12223.8 KXH40029.1 - 2e-10 41.1 12.6 0.0005 20.6 3.9 3.1 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) zf-C2H2 PF00096.26 KXH40032.1 - 0.013 15.9 3.2 0.041 14.4 3.2 1.9 1 0 0 1 1 1 0 Zinc finger, C2H2 type DUF1604 PF07713.13 KXH40032.1 - 0.037 13.8 2.9 0.1 12.4 2.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1604) Pkinase PF00069.25 KXH40035.1 - 2.9e-43 148.1 0.0 2.8e-40 138.3 0.0 2.7 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXH40035.1 - 1.3e-14 54.1 0.0 1.8e-08 34.0 0.0 3.7 4 0 0 4 4 4 2 Protein tyrosine kinase APH PF01636.23 KXH40035.1 - 1.7e-05 24.9 0.1 0.095 12.6 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXH40035.1 - 0.00045 19.1 0.1 0.0013 17.6 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 KXH40035.1 - 0.012 15.0 0.0 0.64 9.3 0.0 2.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KXH40035.1 - 0.038 13.3 0.0 4.4 6.5 0.0 2.3 2 0 0 2 2 2 0 Kinase-like Pyr_redox_3 PF13738.6 KXH40035.1 - 0.17 11.1 0.2 0.26 10.5 0.2 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Ribosomal_L27A PF00828.19 KXH40036.1 - 1.7e-21 77.2 0.0 2.3e-21 76.8 0.0 1.2 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Helicase_C_2 PF13307.6 KXH40037.1 - 6e-59 199.0 0.0 2.4e-58 197.1 0.0 2.1 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.15 KXH40037.1 - 5.4e-47 159.7 0.0 9.1e-47 158.9 0.0 1.4 1 0 0 1 1 1 1 DEAD_2 ResIII PF04851.15 KXH40037.1 - 0.024 14.6 0.0 8.1 6.4 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KXH40037.1 - 0.084 13.1 0.0 17 5.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain Goodbye PF17109.5 KXH40038.1 - 8.4e-25 87.6 0.4 3.8e-24 85.5 0.0 2.3 2 0 0 2 2 2 1 fungal STAND N-terminal Goodbye domain TPR_12 PF13424.6 KXH40038.1 - 1.9e-12 47.3 1.0 1.4e-05 25.3 0.1 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KXH40038.1 - 7.3e-10 38.3 6.8 0.009 15.8 0.2 4.4 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 KXH40038.1 - 5.1e-09 35.5 7.1 0.27 11.4 0.0 5.4 5 0 0 5 5 4 4 Tetratricopeptide repeat TPR_8 PF13181.6 KXH40038.1 - 7.7e-07 28.8 3.2 0.012 15.8 0.2 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat AAA_16 PF13191.6 KXH40038.1 - 1.1e-05 25.9 0.1 7.6e-05 23.2 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain TPR_2 PF07719.17 KXH40038.1 - 1.8e-05 24.5 4.8 1.3 9.3 0.0 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 KXH40038.1 - 2.7e-05 24.6 0.6 1.5 9.4 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat NACHT PF05729.12 KXH40038.1 - 7.9e-05 22.6 0.0 0.0002 21.4 0.0 1.7 1 0 0 1 1 1 1 NACHT domain TPR_10 PF13374.6 KXH40038.1 - 0.0031 17.3 0.8 13 5.8 0.2 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat AAA_22 PF13401.6 KXH40038.1 - 0.0032 17.8 0.1 0.042 14.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain TPR_6 PF13174.6 KXH40038.1 - 0.0054 17.3 0.9 17 6.3 0.1 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat RNA_helicase PF00910.22 KXH40038.1 - 0.015 15.7 0.1 0.68 10.4 0.0 2.9 2 0 0 2 2 2 0 RNA helicase TPR_14 PF13428.6 KXH40038.1 - 0.018 15.9 5.8 20 6.4 0.0 5.6 5 1 1 6 6 4 0 Tetratricopeptide repeat DUF2075 PF09848.9 KXH40038.1 - 0.026 13.8 0.0 0.058 12.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) FlgN PF05130.12 KXH40038.1 - 0.1 13.1 3.1 0.56 10.7 0.2 3.4 3 0 0 3 3 3 0 FlgN protein SnoaL_2 PF12680.7 KXH40040.1 - 3e-06 27.8 0.0 3.8e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 KXH40040.1 - 0.0048 16.7 0.0 0.039 13.8 0.0 2.0 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase Glyco_hydro_43 PF04616.14 KXH40041.1 - 4.4e-63 213.3 11.0 3.5e-55 187.4 3.5 2.3 2 0 0 2 2 2 2 Glycosyl hydrolases family 43 Laminin_G_3 PF13385.6 KXH40041.1 - 8.9e-20 71.4 2.4 3.4e-19 69.5 1.4 2.6 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily Glyco_hydro_32N PF00251.20 KXH40041.1 - 3.3e-08 33.5 6.4 0.00048 19.8 0.3 3.2 3 0 0 3 3 3 2 Glycosyl hydrolases family 32 N-terminal domain Sialidase PF02973.16 KXH40041.1 - 0.0013 18.3 0.1 0.0026 17.3 0.1 1.4 1 0 0 1 1 1 1 Sialidase, N-terminal domain DUF1080 PF06439.11 KXH40041.1 - 0.11 12.6 0.4 0.43 10.7 0.4 2.0 1 1 0 1 1 1 0 Domain of Unknown Function (DUF1080) Pectate_lyase PF03211.13 KXH40042.1 - 2.6e-84 281.8 10.9 2.9e-84 281.7 10.9 1.0 1 0 0 1 1 1 1 Pectate lyase HAD_2 PF13419.6 KXH40044.1 - 8.4e-10 39.0 0.0 1.8e-09 38.0 0.0 1.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KXH40044.1 - 8.8e-10 39.2 0.0 5.3e-08 33.4 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KXH40044.1 - 3.9e-06 26.8 0.0 6.7e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like DUF3226 PF11536.8 KXH40044.1 - 0.012 15.3 0.0 0.026 14.2 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3226) HTH_1 PF00126.27 KXH40044.1 - 0.12 12.4 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family NmrA PF05368.13 KXH40045.1 - 9.2e-18 64.7 0.2 1.1e-17 64.4 0.2 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXH40045.1 - 4e-14 52.9 0.6 6.4e-14 52.3 0.1 1.6 2 0 0 2 2 2 1 NAD(P)H-binding DapB_N PF01113.20 KXH40045.1 - 0.0078 16.3 0.1 0.015 15.4 0.1 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus adh_short PF00106.25 KXH40046.1 - 1.1e-30 106.5 0.0 4e-23 81.9 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXH40046.1 - 1.4e-19 70.5 0.0 2.6e-14 53.4 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH40046.1 - 5.5e-10 39.4 0.0 8.3e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 KXH40046.1 - 0.00066 19.9 0.1 0.0013 19.0 0.1 1.5 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain GDP_Man_Dehyd PF16363.5 KXH40046.1 - 0.0024 17.3 0.1 0.026 13.9 0.1 2.0 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KXH40046.1 - 0.0034 16.9 0.2 0.016 14.7 0.2 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KXH40046.1 - 0.02 14.1 0.0 0.026 13.7 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 KXH40046.1 - 0.049 13.5 0.0 0.14 12.0 0.0 1.8 2 0 0 2 2 2 0 NAD(P)H-binding T6SS_VasJ PF16989.5 KXH40047.1 - 0.21 11.1 0.0 0.4 10.1 0.0 1.4 1 0 0 1 1 1 0 Type VI secretion, EvfE, EvfF, ImpA, BimE, VC_A0119, VasJ Abhydrolase_2 PF02230.16 KXH40048.1 - 4.5e-14 52.8 0.0 5.8e-07 29.5 0.0 2.0 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 KXH40048.1 - 1.3e-05 24.8 0.0 0.00019 21.0 0.0 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family BAAT_C PF08840.11 KXH40048.1 - 0.00067 19.6 0.0 0.0026 17.7 0.0 1.8 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal LIP PF03583.14 KXH40048.1 - 0.0093 15.3 0.1 0.033 13.5 0.0 1.7 2 0 0 2 2 2 1 Secretory lipase Hydrolase_4 PF12146.8 KXH40048.1 - 0.0094 15.2 0.0 0.16 11.2 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 KXH40048.1 - 0.032 14.3 0.0 0.91 9.7 0.0 2.2 2 0 0 2 2 2 0 TAP-like protein NAD_binding_10 PF13460.6 KXH40049.1 - 4.2e-19 69.2 0.0 5.4e-19 68.8 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KXH40049.1 - 0.014 14.9 0.0 0.02 14.4 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family Abhydrolase_6 PF12697.7 KXH40050.1 - 0.0011 19.6 2.0 0.0026 18.4 0.8 2.2 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXH40050.1 - 0.044 13.4 0.0 0.1 12.2 0.0 1.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold DUF3810 PF12725.7 KXH40050.1 - 0.092 12.1 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) HET PF06985.11 KXH40051.1 - 7.4e-13 49.1 8.2 2e-11 44.4 1.4 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) DUF2370 PF10176.9 KXH40052.1 - 6.3e-90 300.8 0.9 1.5e-89 299.6 0.0 1.9 2 1 1 3 3 3 1 Protein of unknown function (DUF2370) CD99L2 PF12301.8 KXH40052.1 - 0.28 11.5 4.4 0.62 10.3 4.4 1.5 1 0 0 1 1 1 0 CD99 antigen like protein 2 Mito_carr PF00153.27 KXH40054.1 - 3.9e-51 171.0 5.6 1.1e-21 76.5 0.3 4.0 4 0 0 4 4 4 4 Mitochondrial carrier protein Fer4 PF00037.27 KXH40058.1 - 9.7e-14 50.5 16.5 4.7e-08 32.5 3.6 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 KXH40058.1 - 5.5e-13 49.3 10.3 8.9e-13 48.6 10.3 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.6 KXH40058.1 - 3.7e-10 39.8 31.2 3.6e-06 27.0 12.1 2.1 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_16 PF13484.6 KXH40058.1 - 2.2e-09 38.1 11.9 8.1e-05 23.5 0.7 2.5 2 1 1 3 3 2 2 4Fe-4S double cluster binding domain Fer4_10 PF13237.6 KXH40058.1 - 4.2e-09 36.4 21.2 1.5e-06 28.2 12.2 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 KXH40058.1 - 2.6e-08 33.9 10.2 5.4e-08 32.9 10.2 1.5 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 KXH40058.1 - 2.8e-07 30.9 19.4 0.00011 22.6 11.1 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 KXH40058.1 - 8.9e-07 28.7 17.1 0.00031 20.7 5.4 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 KXH40058.1 - 2.3e-06 27.4 11.4 0.0065 16.5 1.5 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 KXH40058.1 - 4.5e-06 26.8 11.1 0.00023 21.4 1.8 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 KXH40058.1 - 0.00024 21.6 11.9 0.035 14.6 13.0 2.3 1 1 2 3 3 3 3 4Fe-4S dicluster domain c-SKI_SMAD_bind PF08782.10 KXH40058.1 - 0.0069 16.6 5.9 0.38 11.0 0.3 2.4 1 1 1 2 2 2 2 c-SKI Smad4 binding domain ETF_QO PF05187.13 KXH40058.1 - 0.036 14.2 5.7 0.15 12.2 0.4 2.2 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_13 PF13370.6 KXH40058.1 - 0.042 14.4 15.1 0.59 10.7 4.3 2.7 2 1 1 3 3 3 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_18 PF13746.6 KXH40058.1 - 0.051 13.8 9.0 0.84 9.9 1.4 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 KXH40058.1 - 0.16 13.0 15.5 0.33 12.0 3.3 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_22 PF17179.4 KXH40058.1 - 0.45 11.4 12.0 1.7 9.5 1.7 2.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain Ank_2 PF12796.7 KXH40113.1 - 1.4e-30 105.7 0.2 1.1e-11 45.1 0.7 5.9 2 2 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXH40113.1 - 1.4e-26 92.5 3.2 2.5e-08 34.3 0.0 7.0 4 1 4 8 8 8 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXH40113.1 - 7.6e-22 75.1 4.8 0.008 16.6 0.2 10.1 10 0 0 10 10 10 5 Ankyrin repeat Ank PF00023.30 KXH40113.1 - 1.2e-14 54.0 8.3 0.0026 18.2 0.4 6.7 6 1 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 KXH40113.1 - 1.4e-14 53.9 10.2 0.055 13.8 0.1 7.3 3 3 5 8 8 8 7 Ankyrin repeats (many copies) Helo_like_N PF17111.5 KXH40113.1 - 4.9e-07 29.3 0.0 1.1e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins NACHT PF05729.12 KXH40113.1 - 2.6e-05 24.2 0.1 7.6e-05 22.7 0.1 1.8 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 KXH40113.1 - 0.00023 21.5 0.0 0.00056 20.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KXH40113.1 - 0.0019 18.6 0.2 0.0079 16.6 0.1 2.2 2 0 0 2 2 2 1 AAA ATPase domain KAP_NTPase PF07693.14 KXH40113.1 - 0.019 14.2 0.4 0.058 12.6 0.4 1.7 1 1 0 1 1 1 0 KAP family P-loop domain DDE_Tnp_IS66 PF03050.14 KXH40113.1 - 0.023 14.2 0.0 0.052 13.0 0.0 1.5 1 0 0 1 1 1 0 Transposase IS66 family ATPase PF06745.13 KXH40113.1 - 0.14 11.5 0.0 0.29 10.5 0.0 1.4 1 0 0 1 1 1 0 KaiC Chromo PF00385.24 KXH40114.1 - 8.2e-05 22.4 6.4 0.019 14.9 0.3 2.5 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Citrate_bind PF16114.5 KXH40134.1 - 7.1e-88 292.7 0.0 9.9e-88 292.3 0.0 1.2 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding ATP-grasp_2 PF08442.10 KXH40134.1 - 2.8e-08 33.6 0.0 4.3e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain Reovirus_M2 PF05993.12 KXH40134.1 - 0.0015 16.8 0.0 0.0022 16.2 0.0 1.2 1 0 0 1 1 1 1 Reovirus major virion structural protein Mu-1/Mu-1C (M2) Citrate_synt PF00285.21 KXH40135.1 - 3.1e-21 75.9 0.0 3.6e-18 65.8 0.0 2.8 1 1 1 2 2 2 2 Citrate synthase, C-terminal domain CoA_binding PF02629.19 KXH40135.1 - 3.9e-19 69.1 0.1 2.5e-18 66.5 0.0 2.2 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 KXH40135.1 - 3.8e-14 52.8 0.1 6.4e-14 52.0 0.1 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 KXH40135.1 - 5.5e-06 26.2 0.0 9.7e-05 22.2 0.0 2.3 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain Ribosomal_L30 PF00327.20 KXH40136.1 - 5.4e-16 58.2 0.1 6.8e-16 57.9 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e IL11 PF07400.11 KXH40136.1 - 0.14 11.7 0.0 0.19 11.4 0.0 1.1 1 0 0 1 1 1 0 Interleukin 11 MRG PF05712.13 KXH40137.1 - 1.8e-63 213.4 0.1 2.5e-63 213.0 0.1 1.1 1 0 0 1 1 1 1 MRG MRI PF15325.6 KXH40137.1 - 0.02 16.0 1.3 0.04 15.0 1.3 1.5 1 0 0 1 1 1 0 Modulator of retrovirus infection Tudor-knot PF11717.8 KXH40138.1 - 6.6e-09 35.5 0.2 1.9e-08 34.1 0.2 1.9 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo PF00385.24 KXH40138.1 - 0.049 13.5 0.5 0.16 11.9 0.5 1.9 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Cnl2_NKP2 PF09447.10 KXH40139.1 - 6.8e-27 93.4 0.9 7.3e-26 90.1 0.6 2.2 2 0 0 2 2 2 1 Cnl2/NKP2 family protein Malate_synthase PF01274.22 KXH40139.1 - 0.007 14.7 0.6 0.0081 14.5 0.6 1.1 1 0 0 1 1 1 1 Malate synthase Prefoldin_2 PF01920.20 KXH40139.1 - 0.0099 15.8 0.3 0.0099 15.8 0.3 2.2 2 1 0 2 2 2 1 Prefoldin subunit DASH_Spc19 PF08287.11 KXH40139.1 - 0.02 14.8 5.2 0.034 14.0 0.1 2.1 2 0 0 2 2 2 0 Spc19 DUF4407 PF14362.6 KXH40139.1 - 0.027 13.8 1.9 0.034 13.5 1.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) BORCS6 PF10157.9 KXH40139.1 - 0.042 14.1 0.2 0.06 13.6 0.2 1.3 1 1 0 1 1 1 0 BLOC-1-related complex sub-unit 6 DUF5082 PF16888.5 KXH40139.1 - 0.052 13.8 5.9 0.57 10.5 6.1 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) ACCA PF03255.14 KXH40139.1 - 0.061 13.2 2.0 1.9 8.4 0.0 2.1 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit YabA PF06156.13 KXH40139.1 - 0.061 14.0 2.4 6.1 7.5 0.6 2.1 2 0 0 2 2 2 0 Initiation control protein YabA V_ATPase_I PF01496.19 KXH40139.1 - 0.12 10.3 2.2 0.15 10.0 2.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FlaC_arch PF05377.11 KXH40139.1 - 0.17 12.3 2.6 0.17 12.3 0.9 1.8 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Qua1 PF16274.5 KXH40139.1 - 0.18 11.7 6.0 1.4 8.8 0.4 2.6 2 1 0 2 2 2 0 Qua1 domain Nnf1 PF03980.14 KXH40139.1 - 0.21 12.0 6.1 0.27 11.6 3.2 2.1 1 1 0 2 2 2 0 Nnf1 TMCO5 PF14992.6 KXH40139.1 - 0.25 10.9 4.7 0.56 9.7 4.5 1.7 1 1 0 1 1 1 0 TMCO5 family DivIC PF04977.15 KXH40139.1 - 0.35 10.7 0.1 0.35 10.7 0.1 2.3 2 1 0 2 2 2 0 Septum formation initiator Mis12 PF05859.12 KXH40139.1 - 0.36 10.9 3.4 7.5 6.6 3.0 2.5 1 1 1 2 2 2 0 Mis12 protein PspA_IM30 PF04012.12 KXH40139.1 - 0.84 9.2 11.4 0.27 10.8 1.3 2.2 1 1 0 2 2 2 0 PspA/IM30 family NRBF2 PF08961.10 KXH40139.1 - 0.91 9.1 7.1 0.58 9.7 0.4 2.1 1 1 1 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator DUF1192 PF06698.11 KXH40139.1 - 2.6 8.2 12.0 0.14 12.3 1.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1192) CENP-Q PF13094.6 KXH40141.1 - 1.7e-52 178.0 0.8 1.7e-52 178.0 0.8 4.0 2 1 0 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit SAP130_C PF16014.5 KXH40142.1 - 0.012 14.8 4.1 0.014 14.5 4.1 1.1 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus DUF202 PF02656.15 KXH40146.1 - 4.7e-22 78.2 1.0 4.7e-22 78.2 1.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) AAA_11 PF13086.6 KXH40147.1 - 2e-59 201.5 0.8 4e-59 200.5 0.2 1.9 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.6 KXH40147.1 - 5.6e-55 186.0 0.0 3.1e-54 183.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KXH40147.1 - 4.6e-11 42.8 0.0 1e-09 38.4 0.0 2.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KXH40147.1 - 1.5e-08 35.1 0.0 6.5e-08 33.0 0.0 2.2 3 0 0 3 3 1 1 AAA domain Viral_helicase1 PF01443.18 KXH40147.1 - 9.3e-07 28.8 0.0 0.16 11.7 0.0 3.3 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 KXH40147.1 - 2.6e-06 27.5 0.0 2.7e-05 24.2 0.0 2.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.9 KXH40147.1 - 2.7e-06 26.9 0.7 1.2e-05 24.8 0.7 2.0 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) UvrD-helicase PF00580.21 KXH40147.1 - 6.6e-05 22.6 0.1 0.002 17.7 0.0 2.2 1 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_22 PF13401.6 KXH40147.1 - 0.00019 21.7 0.5 0.011 16.0 0.5 2.7 1 1 0 1 1 1 1 AAA domain Helicase_RecD PF05127.14 KXH40147.1 - 0.0011 18.9 0.0 0.2 11.5 0.0 2.4 2 0 0 2 2 2 1 Helicase AAA_25 PF13481.6 KXH40147.1 - 0.0032 17.1 0.6 0.35 10.4 0.0 3.6 3 1 1 4 4 4 1 AAA domain AAA_16 PF13191.6 KXH40147.1 - 0.0035 17.7 0.1 0.011 16.2 0.1 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KXH40147.1 - 0.0078 16.6 0.2 0.11 12.9 0.0 2.8 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 KXH40147.1 - 0.0082 15.2 0.0 0.017 14.2 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein Flavi_DEAD PF07652.14 KXH40147.1 - 0.028 14.4 0.0 0.11 12.5 0.0 1.9 2 0 0 2 2 2 0 Flavivirus DEAD domain PhoH PF02562.16 KXH40147.1 - 0.031 13.7 0.0 0.68 9.3 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein IstB_IS21 PF01695.17 KXH40147.1 - 0.035 13.8 0.0 0.1 12.3 0.0 1.8 1 0 0 1 1 1 0 IstB-like ATP binding protein UvrD_C_2 PF13538.6 KXH40147.1 - 0.071 12.9 0.0 0.69 9.8 0.0 2.4 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain AAA_24 PF13479.6 KXH40147.1 - 0.089 12.5 0.1 0.44 10.2 0.1 2.1 1 1 0 1 1 1 0 AAA domain UvrD_C PF13361.6 KXH40147.1 - 0.12 11.8 0.5 2.2 7.6 0.0 2.7 2 1 1 3 3 3 0 UvrD-like helicase C-terminal domain SHR3_chaperone PF08229.11 KXH40149.1 - 2.3e-67 225.7 0.0 2.6e-67 225.5 0.0 1.0 1 0 0 1 1 1 1 ER membrane protein SH3 DUF5453 PF17534.2 KXH40149.1 - 0.093 12.7 1.3 0.21 11.5 0.6 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5453) tRNA-synt_1 PF00133.22 KXH40150.1 - 9.2e-217 721.0 0.0 1.2e-215 717.4 0.0 2.2 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KXH40150.1 - 2.7e-31 108.6 0.1 1.3e-30 106.4 0.1 2.2 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1_2 PF13603.6 KXH40150.1 - 7.5e-12 45.1 0.1 1.7e-08 34.2 0.0 2.9 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.11 KXH40150.1 - 1.4e-11 43.8 0.0 0.00019 20.3 0.0 4.2 4 1 0 4 4 4 3 tRNA synthetases class I (M) Val_tRNA-synt_C PF10458.9 KXH40150.1 - 0.0071 16.6 7.8 0.0071 16.6 7.8 3.7 3 0 0 3 3 3 1 Valyl tRNA synthetase tRNA binding arm DUF1932 PF09130.11 KXH40152.1 - 1.4e-26 92.2 0.2 3.3e-26 91.0 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1932) NAD_binding_2 PF03446.15 KXH40152.1 - 1.6e-08 34.9 0.0 2.8e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KXH40152.1 - 9.7e-08 32.5 0.2 3e-07 30.9 0.2 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 KXH40152.1 - 0.0019 18.1 0.1 0.0034 17.3 0.1 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 KXH40152.1 - 0.019 14.3 0.0 0.03 13.7 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain YjeF_N PF03853.15 KXH40152.1 - 0.029 14.3 0.0 0.052 13.4 0.0 1.4 1 0 0 1 1 1 0 YjeF-related protein N-terminus RRM_1 PF00076.22 KXH40154.1 - 8.9e-12 44.7 0.2 3.3e-10 39.6 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 KXH40154.1 - 0.0063 17.0 25.3 0.0063 17.0 25.3 5.0 4 2 2 6 6 6 1 C-terminal duplication domain of Friend of PRMT1 Anp1 PF03452.14 KXH40155.1 - 2e-109 365.1 0.0 2.4e-109 364.8 0.0 1.0 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.26 KXH40155.1 - 0.024 14.4 0.0 0.041 13.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 2 UQ_con PF00179.26 KXH40156.1 - 8.7e-29 100.0 0.0 1.1e-28 99.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme SR-25 PF10500.9 KXH40157.1 - 1 8.9 30.9 0.011 15.4 9.8 2.8 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein WD40 PF00400.32 KXH40279.1 - 1.4e-11 44.7 8.6 1.7 9.7 0.0 8.9 10 0 0 10 10 10 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXH40279.1 - 7.5e-06 26.2 0.2 3.3 8.1 0.1 5.8 5 2 0 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 KXH40279.1 - 0.023 14.3 7.8 0.089 12.4 0.1 3.5 2 1 2 4 4 4 0 PQQ-like domain PQQ PF01011.21 KXH40279.1 - 0.083 12.9 0.3 0.68 10.0 0.1 2.7 2 0 0 2 2 2 0 PQQ enzyme repeat RAB3GAP2_N PF14655.6 KXH40279.1 - 0.13 11.5 0.1 19 4.4 0.0 3.1 2 1 1 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Tub_N PF16322.5 KXH40279.1 - 0.21 12.0 5.9 4.1 7.8 0.2 2.3 2 0 0 2 2 2 0 Tubby N-terminal SDA1 PF05285.12 KXH40279.1 - 2.7 7.3 9.2 6.6 6.0 1.9 2.1 2 0 0 2 2 2 0 SDA1 NAPRTase PF04095.16 KXH40280.1 - 1.5e-59 201.5 0.3 6.6e-31 107.8 0.3 2.1 2 0 0 2 2 2 2 Nicotinate phosphoribosyltransferase (NAPRTase) family NAPRTase_N PF17767.1 KXH40280.1 - 2.7e-36 124.7 0.1 5e-36 123.9 0.1 1.5 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain ECH_2 PF16113.5 KXH40285.1 - 1.1e-126 422.9 0.0 1.8e-126 422.2 0.0 1.4 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 KXH40285.1 - 2.8e-31 108.7 0.0 2.4e-26 92.6 0.0 2.3 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase WHEP-TRS PF00458.20 KXH40285.1 - 0.49 10.6 3.3 8.5 6.6 0.1 2.4 2 0 0 2 2 2 0 WHEP-TRS domain GATA PF00320.27 KXH40286.1 - 0.054 13.1 9.1 0.11 12.1 1.8 2.5 2 0 0 2 2 2 0 GATA zinc finger PBP PF01161.20 KXH40287.1 - 4.3e-09 36.8 0.0 8.6e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Ribosomal_L4 PF00573.22 KXH40288.1 - 6e-47 159.8 0.0 7.9e-47 159.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family DUF3604 PF12228.8 KXH40288.1 - 0.11 10.9 0.0 0.16 10.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3604) bZIP_1 PF00170.21 KXH40289.1 - 1.1e-11 44.6 2.4 1.8e-11 44.0 2.4 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KXH40289.1 - 1.9e-06 27.8 2.4 3.6e-06 27.0 2.4 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KXH40289.1 - 0.0011 19.4 2.6 0.0022 18.5 2.6 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor Phlebovirus_NSM PF07246.11 KXH40289.1 - 0.11 11.9 1.1 0.16 11.3 1.1 1.2 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M DUF4407 PF14362.6 KXH40289.1 - 0.18 11.1 0.3 0.25 10.6 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Rep_fac-A_3 PF08661.11 KXH40292.1 - 4.7e-15 55.8 0.0 8.9e-15 54.9 0.0 1.4 1 0 0 1 1 1 1 Replication factor A protein 3 HAP1_N PF04849.13 KXH40293.1 - 0.0078 15.5 0.6 0.014 14.6 0.6 1.3 1 0 0 1 1 1 1 HAP1 N-terminal conserved region PKcGMP_CC PF16808.5 KXH40293.1 - 0.057 13.3 1.0 0.13 12.1 1.0 1.5 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase ADIP PF11559.8 KXH40293.1 - 0.11 12.5 3.8 0.27 11.3 3.8 1.6 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding GIT_CC PF16559.5 KXH40293.1 - 0.16 11.9 1.7 0.37 10.7 1.7 1.6 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor RhoGAP PF00620.27 KXH40294.1 - 1.2e-07 31.7 0.0 2e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain CBS PF00571.28 KXH40295.1 - 3e-26 91.6 7.7 4.5e-11 43.0 0.3 4.4 4 0 0 4 4 4 4 CBS domain Arm PF00514.23 KXH40296.1 - 8.1e-68 222.6 32.1 4.1e-12 45.7 0.2 11.3 10 2 1 11 11 11 9 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KXH40296.1 - 1.3e-17 63.9 10.5 0.00013 22.3 0.2 7.3 6 1 1 7 7 7 5 HEAT-like repeat HEAT PF02985.22 KXH40296.1 - 3.7e-15 54.7 13.5 0.1 12.9 0.2 8.0 9 0 0 9 9 8 5 HEAT repeat HEAT_2 PF13646.6 KXH40296.1 - 1.4e-14 54.2 10.2 0.0016 18.8 0.1 7.1 2 2 2 6 6 6 4 HEAT repeats Arm_2 PF04826.13 KXH40296.1 - 2.7e-09 36.9 9.5 0.00085 18.9 0.1 3.5 3 1 1 4 4 4 3 Armadillo-like V-ATPase_H_N PF03224.14 KXH40296.1 - 7.7e-08 32.0 2.1 0.00082 18.7 1.0 3.1 2 1 1 3 3 3 2 V-ATPase subunit H Adaptin_N PF01602.20 KXH40296.1 - 2.6e-07 29.6 10.7 0.00028 19.6 3.1 3.4 2 1 2 4 4 4 3 Adaptin N terminal region KAP PF05804.12 KXH40296.1 - 3.1e-06 25.6 0.2 8.7e-05 20.9 0.1 2.2 1 1 1 2 2 2 1 Kinesin-associated protein (KAP) V-ATPase_H_C PF11698.8 KXH40296.1 - 0.00034 20.7 1.2 6.1 7.0 0.2 4.8 3 1 4 7 7 7 1 V-ATPase subunit H DUF5578 PF17741.1 KXH40296.1 - 0.00046 19.7 7.1 1.7 8.0 0.2 5.2 3 2 3 6 6 6 2 Family of unknown function (DUF5578) IFRD PF05004.13 KXH40296.1 - 0.0013 17.9 4.0 1.6 7.8 0.1 4.0 3 1 1 4 4 4 2 Interferon-related developmental regulator (IFRD) DUF3361 PF11841.8 KXH40296.1 - 0.0045 16.9 8.7 1 9.3 0.1 3.7 2 1 0 4 4 4 2 Domain of unknown function (DUF3361) Atx10homo_assoc PF09759.9 KXH40296.1 - 0.021 14.8 7.1 5.3 7.1 0.3 4.6 4 1 1 5 5 5 0 Spinocerebellar ataxia type 10 protein domain Vac14_Fab1_bd PF12755.7 KXH40296.1 - 0.034 14.7 0.0 1.3 9.7 0.0 3.0 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region HEAT_PBS PF03130.16 KXH40296.1 - 0.074 13.8 7.3 42 5.2 0.1 6.6 6 0 0 6 6 6 0 PBS lyase HEAT-like repeat UNC45-central PF11701.8 KXH40296.1 - 0.4 10.6 3.6 5.3 7.0 0.4 3.6 3 1 1 4 4 4 0 Myosin-binding striated muscle assembly central Peptidase_S24 PF00717.23 KXH40297.1 - 1.2e-06 28.3 0.1 1.9e-06 27.7 0.1 1.3 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 KXH40297.1 - 1e-05 25.3 0.0 0.00029 20.6 0.0 2.4 1 1 1 2 2 2 1 Signal peptidase, peptidase S26 IF3_C PF00707.22 KXH40298.1 - 1.5e-08 34.5 0.6 3e-08 33.5 0.6 1.5 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain mIF3 PF14877.6 KXH40298.1 - 1.2e-06 28.4 0.9 4.2e-05 23.3 0.9 2.1 1 1 0 1 1 1 1 Mitochondrial translation initiation factor IF3_N PF05198.16 KXH40298.1 - 0.0005 20.3 0.8 0.0019 18.4 0.3 2.1 1 1 1 2 2 2 1 Translation initiation factor IF-3, N-terminal domain Ribosomal_L36e PF01158.18 KXH40298.1 - 0.0096 16.1 0.5 0.0096 16.1 0.5 1.7 2 0 0 2 2 2 1 Ribosomal protein L36e IF-2B PF01008.17 KXH40299.1 - 8.8e-47 159.6 0.0 2.2e-46 158.3 0.0 1.6 1 1 0 1 1 1 1 Initiation factor 2 subunit family CNTF PF01110.17 KXH40299.1 - 0.047 13.1 0.2 0.17 11.2 0.0 1.9 2 0 0 2 2 2 0 Ciliary neurotrophic factor PLDc_2 PF13091.6 KXH40301.1 - 3e-16 59.5 0.0 1.3e-07 31.6 0.0 2.5 2 1 0 2 2 2 2 PLD-like domain PLDc PF00614.22 KXH40301.1 - 4.5e-08 33.0 2.4 0.0065 16.6 0.4 3.2 2 1 0 2 2 2 2 Phospholipase D Active site motif DnaG_DnaB_bind PF08278.11 KXH40301.1 - 0.055 14.1 0.0 0.16 12.6 0.0 1.7 1 0 0 1 1 1 0 DNA primase DnaG DnaB-binding PhzC-PhzF PF02567.16 KXH40301.1 - 0.18 11.2 0.0 0.31 10.5 0.0 1.3 1 0 0 1 1 1 0 Phenazine biosynthesis-like protein NDUFA12 PF05071.16 KXH40302.1 - 1.9e-31 108.7 1.2 2.3e-31 108.5 1.2 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 TGT PF01702.18 KXH40303.1 - 1.1e-59 202.4 0.0 1.3e-59 202.2 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase PE_PPE_C PF12484.8 KXH40303.1 - 0.15 13.0 2.5 1.9 9.5 0.0 2.6 2 0 0 2 2 2 0 Polymorphic PE/PPE proteins C terminal AMP-binding PF00501.28 KXH40304.1 - 3.2e-71 240.1 0.0 5.1e-71 239.5 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 KXH40304.1 - 6.7e-59 199.1 0.0 1.3e-58 198.2 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein adh_short PF00106.25 KXH40304.1 - 9.9e-53 178.5 3.9 1.2e-52 178.2 2.2 1.9 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXH40304.1 - 1.2e-39 136.3 1.6 2.2e-39 135.4 1.6 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH40304.1 - 3.8e-20 72.5 2.7 2.7e-15 56.7 1.2 2.4 2 0 0 2 2 2 2 KR domain Epimerase PF01370.21 KXH40304.1 - 5.4e-15 55.5 1.4 1.1e-08 34.8 0.0 3.7 3 2 0 3 3 3 2 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KXH40304.1 - 2.2e-11 43.9 0.0 5.9e-11 42.6 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site NAD_binding_10 PF13460.6 KXH40304.1 - 3.8e-06 26.9 1.0 0.00028 20.8 0.6 2.8 3 0 0 3 3 3 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KXH40304.1 - 8.1e-06 25.0 0.3 0.00074 18.6 0.0 3.0 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KXH40304.1 - 1.5e-05 24.3 3.0 0.011 14.9 0.1 4.0 3 1 0 3 3 3 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KXH40304.1 - 8.5e-05 21.8 1.1 0.46 9.6 0.0 3.2 3 1 0 3 3 3 2 Polysaccharide biosynthesis protein AMP-binding_C PF13193.6 KXH40304.1 - 0.0025 18.7 0.1 0.02 15.9 0.0 2.7 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain GDP_Man_Dehyd PF16363.5 KXH40304.1 - 0.0051 16.3 0.1 1.8 7.9 0.0 2.5 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase DFP PF04127.15 KXH40304.1 - 0.007 16.2 1.1 0.017 15.0 1.1 1.5 1 0 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein NmrA PF05368.13 KXH40304.1 - 0.01 15.4 2.9 2.7 7.5 0.0 2.7 3 0 0 3 3 3 0 NmrA-like family THF_DHG_CYH_C PF02882.19 KXH40304.1 - 0.011 15.1 0.2 0.029 13.7 0.2 1.7 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DXP_reductoisom PF02670.16 KXH40304.1 - 0.16 12.7 1.7 0.26 12.0 0.0 2.2 2 0 0 2 2 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase LCCL PF03815.19 KXH40305.1 - 5.7e-21 74.4 0.2 9.4e-21 73.7 0.2 1.3 1 0 0 1 1 1 1 LCCL domain HAUS-augmin3 PF14932.6 KXH40307.1 - 0.08 12.5 3.2 0.11 12.0 3.2 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 CtnDOT_TraJ PF07863.11 KXH40307.1 - 1.5 9.5 4.6 5.7 7.7 0.0 2.9 2 0 0 2 2 2 0 Homologues of TraJ from Bacteroides conjugative transposon NPV_P10 PF05531.12 KXH40307.1 - 1.7 9.2 4.4 5 7.7 2.1 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Abhydrolase_2 PF02230.16 KXH40308.1 - 3.5e-11 43.3 0.0 1.2e-10 41.5 0.0 1.9 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase PLAC8 PF04749.17 KXH40309.1 - 7.7e-07 30.0 0.2 1.4e-06 29.2 0.2 1.4 1 0 0 1 1 1 1 PLAC8 family WD40 PF00400.32 KXH40310.1 - 1.5e-21 76.3 14.4 4.8e-05 24.0 0.2 7.4 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXH40310.1 - 4.4e-11 42.9 1.3 0.11 12.8 0.0 5.5 2 2 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_3 PF15911.5 KXH40310.1 - 0.004 17.1 0.0 0.074 13.1 0.0 2.6 2 0 0 2 2 2 1 WD domain, G-beta repeat Dynamin_M PF01031.20 KXH40311.1 - 2.6e-101 338.6 0.0 4.8e-101 337.7 0.0 1.5 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 KXH40311.1 - 7.4e-57 192.1 0.0 1.3e-56 191.2 0.0 1.4 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 KXH40311.1 - 6.3e-30 103.2 4.4 6.3e-30 103.2 4.4 2.2 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KXH40311.1 - 2.2e-05 24.5 0.2 0.00023 21.2 0.2 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF2226 PF09987.9 KXH40311.1 - 0.043 13.2 0.1 11 5.3 0.2 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2226) AAA_15 PF13175.6 KXH40311.1 - 0.049 13.3 0.6 2.4 7.8 0.1 2.4 2 0 0 2 2 2 0 AAA ATPase domain adh_short PF00106.25 KXH40312.1 - 3.4e-20 72.3 0.3 4.8e-17 62.0 0.1 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXH40312.1 - 2.7e-10 40.2 0.4 2.8e-09 36.9 0.4 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH40312.1 - 2.2e-05 24.4 0.1 4.2e-05 23.5 0.1 1.4 1 1 0 1 1 1 1 KR domain DUF1849 PF08904.11 KXH40312.1 - 0.073 12.6 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1849) CoA_transf_3 PF02515.17 KXH40313.1 - 7.2e-69 232.7 0.0 9.1e-69 232.3 0.0 1.1 1 0 0 1 1 1 1 CoA-transferase family III Nudix_N PF12535.8 KXH40313.1 - 0.0092 15.6 0.0 0.024 14.2 0.0 1.7 1 0 0 1 1 1 1 Hydrolase of X-linked nucleoside diphosphate N terminal PAC3 PF10178.9 KXH40314.1 - 7.9e-05 22.7 0.0 0.00011 22.3 0.0 1.2 1 0 0 1 1 1 1 Proteasome assembly chaperone 3 HA2 PF04408.23 KXH40315.1 - 3.9e-26 91.4 0.0 3.9e-26 91.4 0.0 2.6 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KXH40315.1 - 4.7e-12 46.2 0.0 6.5e-11 42.6 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 KXH40315.1 - 1.4e-10 41.4 0.0 3e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 KXH40315.1 - 9.8e-10 38.5 0.0 2.9e-09 36.9 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KXH40315.1 - 4e-05 23.9 0.1 0.00017 21.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KXH40315.1 - 0.00028 20.7 0.0 0.00065 19.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KXH40315.1 - 0.00036 20.9 0.0 0.00079 19.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 KXH40315.1 - 0.011 15.2 0.1 0.025 14.0 0.0 1.6 2 0 0 2 2 2 0 PhoH-like protein T2SSE PF00437.20 KXH40315.1 - 0.02 13.9 0.0 0.052 12.6 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein ATPase PF06745.13 KXH40315.1 - 0.033 13.6 0.7 0.066 12.5 0.1 1.8 2 0 0 2 2 2 0 KaiC ResIII PF04851.15 KXH40315.1 - 0.047 13.7 1.0 0.65 10.0 0.0 2.7 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit DUF2075 PF09848.9 KXH40315.1 - 0.092 12.0 0.6 0.16 11.2 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_33 PF13671.6 KXH40315.1 - 0.25 11.5 1.6 0.77 9.9 0.1 2.3 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KXH40315.1 - 0.4 11.2 3.2 14 6.2 0.0 2.6 2 0 0 2 2 2 0 ABC transporter adh_short_C2 PF13561.6 KXH40316.1 - 8.9e-47 159.6 0.0 1.5e-46 158.9 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXH40316.1 - 1.3e-31 109.6 0.1 5.4e-31 107.6 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KXH40316.1 - 3.6e-05 23.8 0.0 8.6e-05 22.5 0.0 1.7 1 1 0 1 1 1 1 KR domain NmrA PF05368.13 KXH40317.1 - 9.3e-16 58.1 0.0 1.4e-15 57.5 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXH40317.1 - 1.1e-10 41.7 0.0 3e-09 37.0 0.0 2.0 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KXH40317.1 - 0.0056 16.2 0.0 0.015 14.8 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 KXH40317.1 - 0.011 16.1 0.0 0.021 15.3 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain UPF0227 PF05728.12 KXH40317.1 - 0.26 11.2 0.1 19 5.1 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) ABC_tran PF00005.27 KXH40319.1 - 3.7e-46 157.1 0.0 1.5e-22 80.6 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KXH40319.1 - 5.8e-28 98.3 22.9 1.3e-24 87.3 7.7 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.6 KXH40319.1 - 6.3e-13 49.2 4.0 0.1 12.4 0.5 4.3 2 2 2 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KXH40319.1 - 8.2e-10 38.5 0.2 0.0081 15.6 0.0 3.8 3 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KXH40319.1 - 4.7e-06 26.2 1.5 0.072 12.8 0.3 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_33 PF13671.6 KXH40319.1 - 2.4e-05 24.5 0.0 0.00063 19.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 KXH40319.1 - 2.8e-05 24.2 0.9 0.13 12.3 0.5 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 KXH40319.1 - 0.00019 21.8 0.4 1.3 9.4 0.2 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 KXH40319.1 - 0.00038 20.7 0.5 3.1 8.1 0.0 3.3 2 1 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KXH40319.1 - 0.00065 19.6 0.7 0.27 11.1 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_7 PF12775.7 KXH40319.1 - 0.0027 17.2 0.1 0.48 9.9 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_23 PF13476.6 KXH40319.1 - 0.003 18.1 0.1 1.7 9.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 KXH40319.1 - 0.0067 15.5 1.1 1.6 7.7 0.1 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein Dynamin_N PF00350.23 KXH40319.1 - 0.0091 16.1 3.7 1 9.4 0.2 2.4 2 0 0 2 2 2 2 Dynamin family AAA_25 PF13481.6 KXH40319.1 - 0.012 15.2 0.2 5.4 6.5 0.1 3.0 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KXH40319.1 - 0.043 13.1 0.0 1.5 8.1 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_PrkA PF08298.11 KXH40319.1 - 0.055 12.4 0.0 1.1 8.1 0.0 2.2 2 0 0 2 2 2 0 PrkA AAA domain AAA_18 PF13238.6 KXH40319.1 - 0.078 13.5 0.0 7 7.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 KXH40319.1 - 0.083 12.2 0.3 3.2 7.0 0.1 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_15 PF13175.6 KXH40319.1 - 0.083 12.6 0.1 8.6 6.0 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain NB-ARC PF00931.22 KXH40319.1 - 0.085 12.0 0.1 2.9 7.0 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain SbcCD_C PF13558.6 KXH40319.1 - 0.12 12.6 4.3 8.5 6.7 0.1 3.7 3 1 0 3 3 3 0 Putative exonuclease SbcCD, C subunit Mg_chelatase PF01078.21 KXH40319.1 - 0.19 11.1 0.3 5.5 6.3 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DUF87 PF01935.17 KXH40319.1 - 0.32 11.1 0.7 0.7 10.0 0.7 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain Roc PF08477.13 KXH40319.1 - 0.56 10.4 1.9 27 5.0 0.3 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 KXH40319.1 - 4.4 6.9 5.2 20 4.7 0.4 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SUR7 PF06687.12 KXH40320.1 - 9.3e-28 97.3 1.0 1.1e-27 97.1 1.0 1.0 1 0 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.8 KXH40320.1 - 3.9e-09 36.7 2.9 3.9e-09 36.7 2.9 1.7 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 PMP22_Claudin PF00822.20 KXH40320.1 - 1.6 8.6 7.7 0.85 9.5 3.4 2.1 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin family DUF2569 PF10754.9 KXH40320.1 - 1.6 9.2 12.8 1.6 9.2 0.6 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2569) DUF92 PF01940.16 KXH40320.1 - 2.2 7.6 7.2 5.8 6.3 7.2 1.7 1 1 0 1 1 1 0 Integral membrane protein DUF92 MscL PF01741.18 KXH40321.1 - 4.9e-21 75.3 0.2 6.1e-21 74.9 0.2 1.1 1 0 0 1 1 1 1 Large-conductance mechanosensitive channel, MscL zf-BED PF02892.15 KXH40321.1 - 0.0054 16.7 2.8 0.0086 16.1 2.8 1.3 1 0 0 1 1 1 1 BED zinc finger DZR PF12773.7 KXH40321.1 - 0.046 13.7 0.9 0.074 13.1 0.9 1.2 1 0 0 1 1 1 0 Double zinc ribbon C1_1 PF00130.22 KXH40321.1 - 0.06 13.2 2.5 0.093 12.6 2.5 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C3HC4_3 PF13920.6 KXH40321.1 - 0.063 13.1 2.7 0.1 12.5 2.7 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF3043 PF11241.8 KXH40321.1 - 0.14 12.2 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) zinc_ribbon_2 PF13240.6 KXH40321.1 - 1.5 8.6 4.0 2.6 7.9 4.0 1.3 1 0 0 1 1 1 0 zinc-ribbon domain PMT PF02366.18 KXH40322.1 - 0.14 11.7 0.1 0.24 10.9 0.1 1.4 1 0 0 1 1 1 0 Dolichyl-phosphate-mannose-protein mannosyltransferase Sporozoite_P67 PF05642.11 KXH40322.1 - 0.24 9.4 7.6 0.24 9.4 7.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen MSP1_C PF07462.11 KXH40322.1 - 7.8 5.1 9.0 13 4.4 9.0 1.3 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Glyco_hydro_76 PF03663.14 KXH40324.1 - 3.6e-125 418.3 10.3 4.1e-125 418.1 10.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 KXH40324.1 - 1.4 8.0 7.2 1.8 7.6 0.2 2.9 2 1 1 3 3 3 0 Glycosyl Hydrolase Family 88 Aminotran_1_2 PF00155.21 KXH40325.1 - 7.3e-65 219.5 0.0 8.7e-65 219.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Alliinase_C PF04864.13 KXH40325.1 - 0.27 10.1 0.0 0.38 9.6 0.0 1.1 1 0 0 1 1 1 0 Allinase Lipase_GDSL PF00657.22 KXH40326.1 - 1.6e-09 38.0 0.0 2.4e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 KXH40326.1 - 2.3e-06 28.1 1.0 1.1e-05 25.9 0.4 2.1 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Spt20 PF12090.8 KXH40327.1 - 0.0039 16.9 26.0 0.0039 16.9 26.0 2.5 3 0 0 3 3 3 1 Spt20 family SURF6 PF04935.12 KXH40327.1 - 0.013 15.4 16.2 0.021 14.6 16.2 1.2 1 0 0 1 1 1 0 Surfeit locus protein 6 eIF-3_zeta PF05091.12 KXH40327.1 - 0.25 10.3 14.1 0.4 9.6 14.1 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) TERB2 PF15101.6 KXH40327.1 - 1.2 9.2 12.2 2.1 8.4 12.2 1.5 1 0 0 1 1 1 0 Telomere-associated protein TERB2 NARP1 PF12569.8 KXH40327.1 - 1.6 7.5 8.1 2.7 6.8 8.1 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Peptidase_S49_N PF08496.10 KXH40327.1 - 3.1 7.8 6.8 5.6 7.0 6.8 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Presenilin PF01080.17 KXH40327.1 - 5.6 5.6 13.7 9 4.9 13.7 1.3 1 0 0 1 1 1 0 Presenilin DNApol_Exo PF18136.1 KXH40327.1 - 9.3 5.3 11.3 16 4.5 11.3 1.3 1 0 0 1 1 1 0 DNA mitochondrial polymerase exonuclease domain RabGAP-TBC PF00566.18 KXH40328.1 - 1.7e-48 165.2 0.2 9.2e-48 162.7 0.0 2.1 2 0 0 2 2 2 1 Rab-GTPase-TBC domain zf-C4H2 PF10146.9 KXH40328.1 - 0.00071 19.9 4.7 0.00071 19.9 4.7 3.4 3 1 0 3 3 3 1 Zinc finger-containing protein APG6_N PF17675.1 KXH40328.1 - 0.00078 20.0 24.8 0.015 15.8 2.6 4.6 4 0 0 4 4 4 2 Apg6 coiled-coil region Fez1 PF06818.15 KXH40328.1 - 0.0015 19.0 30.4 0.24 11.8 0.2 4.1 3 1 0 3 3 3 3 Fez1 BicD PF09730.9 KXH40328.1 - 0.019 13.4 15.9 0.011 14.2 6.1 2.7 2 0 0 2 2 2 0 Microtubule-associated protein Bicaudal-D RNase_E_G PF10150.9 KXH40328.1 - 0.089 12.2 2.2 0.098 12.1 0.2 2.1 2 0 0 2 2 2 0 Ribonuclease E/G family CENP-K PF11802.8 KXH40328.1 - 0.21 11.2 11.5 1.1 8.8 0.1 2.5 2 0 0 2 2 2 0 Centromere-associated protein K FapA PF03961.13 KXH40328.1 - 0.96 8.0 5.3 0.91 8.1 0.9 2.3 2 0 0 2 2 2 0 Flagellar Assembly Protein A Cnn_1N PF07989.11 KXH40328.1 - 1.4 9.1 22.3 3.3 7.9 0.0 4.7 4 1 1 5 5 5 0 Centrosomin N-terminal motif 1 DUF1465 PF07323.12 KXH40328.1 - 1.5 8.7 8.8 12 5.8 2.9 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1465) SKA2 PF16740.5 KXH40328.1 - 2 8.2 16.5 7.9 6.3 1.3 2.8 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 Tup_N PF08581.10 KXH40328.1 - 2.3 8.6 14.7 2.7 8.3 9.1 3.1 2 0 0 2 2 2 0 Tup N-terminal Macoilin PF09726.9 KXH40328.1 - 2.4 6.6 20.6 0.32 9.5 3.2 2.5 2 0 0 2 2 2 0 Macoilin family Vac_Fusion PF02346.16 KXH40328.1 - 6.4 6.5 6.7 4 7.1 3.6 2.4 2 0 0 2 2 2 0 Chordopoxvirus multifunctional envelope protein A27 Reticulon PF02453.17 KXH40329.1 - 5.3e-34 117.4 2.5 7.4e-34 117.0 2.5 1.2 1 0 0 1 1 1 1 Reticulon DNA_topoisoIV PF00521.20 KXH40330.1 - 2.2e-124 415.7 1.0 5.2e-124 414.4 0.1 2.0 2 0 0 2 2 2 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 KXH40330.1 - 1.2e-48 164.6 3.2 6.9e-48 162.2 3.2 2.5 1 0 0 1 1 1 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 KXH40330.1 - 2.2e-25 89.1 2.5 5.8e-25 87.8 2.5 1.7 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 KXH40330.1 - 1.1e-13 51.7 0.1 3e-13 50.3 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 KXH40330.1 - 1.1e-06 28.7 0.0 5.5e-06 26.5 0.0 2.3 1 0 0 1 1 1 1 Toprim domain Pro_CA PF00484.19 KXH40331.1 - 5.8e-14 52.7 0.1 1.9e-13 51.0 0.1 1.8 1 1 0 1 1 1 1 Carbonic anhydrase Acetyltransf_1 PF00583.25 KXH40332.1 - 6e-10 39.4 0.0 7.6e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXH40332.1 - 6.3e-06 26.1 0.0 8.5e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXH40332.1 - 6.9e-05 22.7 0.0 0.00012 22.0 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 KXH40332.1 - 0.00018 21.9 0.0 0.00026 21.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PLDc_2 PF13091.6 KXH40333.1 - 3.4e-20 72.3 0.0 2.7e-06 27.3 0.0 3.8 3 1 0 3 3 3 3 PLD-like domain PLDc PF00614.22 KXH40333.1 - 1.1e-11 44.4 0.8 1.4e-05 25.0 0.0 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif GAGBD PF16828.5 KXH40333.1 - 0.069 13.3 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 GAG-binding domain on surface antigen Alg14 PF08660.11 KXH40333.1 - 0.22 11.5 0.0 2.2 8.2 0.0 2.2 2 0 0 2 2 2 0 Oligosaccharide biosynthesis protein Alg14 like Thioredoxin PF00085.20 KXH40334.1 - 4.8e-41 138.9 0.0 1.6e-23 82.6 0.0 3.5 3 1 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 KXH40334.1 - 3.2e-08 33.7 0.0 0.00066 19.6 0.0 3.7 1 1 2 3 3 3 2 Thioredoxin-like domain Thioredoxin_2 PF13098.6 KXH40334.1 - 0.00046 20.6 0.4 0.14 12.7 0.1 3.4 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KXH40334.1 - 0.00083 19.6 0.1 0.033 14.5 0.0 3.2 3 0 0 3 3 3 1 Thioredoxin-like Thioredoxin_7 PF13899.6 KXH40334.1 - 0.0067 16.6 0.7 0.11 12.7 0.1 3.1 4 0 0 4 4 3 1 Thioredoxin-like HyaE PF07449.11 KXH40334.1 - 0.01 15.8 0.0 20 5.2 0.0 3.8 4 0 0 4 4 4 0 Hydrogenase-1 expression protein HyaE AhpC-TSA PF00578.21 KXH40334.1 - 0.015 15.2 0.6 0.12 12.3 0.0 2.7 3 0 0 3 3 3 0 AhpC/TSA family OST3_OST6 PF04756.13 KXH40334.1 - 0.065 12.6 0.0 3.1 7.1 0.0 2.8 3 0 0 3 3 3 0 OST3 / OST6 family, transporter family Presenilin PF01080.17 KXH40334.1 - 0.1 11.3 0.2 0.17 10.7 0.2 1.2 1 0 0 1 1 1 0 Presenilin Thioredoxin_3 PF13192.6 KXH40334.1 - 0.22 11.6 1.6 2.8 8.1 0.1 3.4 5 0 0 5 5 5 0 Thioredoxin domain TraF PF13728.6 KXH40334.1 - 0.28 11.0 0.0 0.28 11.0 0.0 4.0 2 1 1 3 3 2 0 F plasmid transfer operon protein Ndc1_Nup PF09531.10 KXH40334.1 - 6 5.4 5.9 8.9 4.9 5.9 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Ank_2 PF12796.7 KXH40335.1 - 2.6e-22 79.2 0.0 4.8e-08 33.5 0.0 4.8 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.30 KXH40335.1 - 2.5e-17 62.5 0.2 1.4e-06 28.5 0.0 6.1 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.6 KXH40335.1 - 3.2e-16 59.5 1.7 5.6e-06 26.8 0.0 6.1 4 2 4 8 8 8 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXH40335.1 - 3.5e-13 49.5 0.7 0.0041 17.4 0.0 5.5 4 1 2 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXH40335.1 - 1.3e-12 46.7 1.0 0.0008 19.7 0.0 7.2 7 0 0 7 7 7 2 Ankyrin repeat Helo_like_N PF17111.5 KXH40335.1 - 5.4e-05 22.7 3.4 0.00017 21.0 3.4 2.0 1 1 0 1 1 1 1 Fungal N-terminal domain of STAND proteins Tyr-DNA_phospho PF06087.12 KXH40336.1 - 1.5e-161 538.1 0.0 1.7e-161 537.9 0.0 1.0 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.6 KXH40336.1 - 0.0085 16.0 0.1 0.84 9.5 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain ACBP PF00887.19 KXH40337.1 - 5.7e-23 80.9 0.5 6.8e-23 80.7 0.5 1.1 1 0 0 1 1 1 1 Acyl CoA binding protein Imm71 PF15602.6 KXH40337.1 - 0.028 14.5 0.0 0.033 14.3 0.0 1.1 1 0 0 1 1 1 0 Immunity protein 71 ChaB PF06150.12 KXH40337.1 - 0.61 10.7 4.5 1.2 9.8 0.2 2.5 2 1 1 3 3 3 0 ChaB HNH_2 PF13391.6 KXH40363.1 - 0.00033 20.7 0.0 0.00085 19.4 0.0 1.7 2 0 0 2 2 2 1 HNH endonuclease TRF PF08558.10 KXH40364.1 - 1.8e-26 93.2 0.6 1.8e-26 93.2 0.6 1.8 2 0 0 2 2 2 1 Telomere repeat binding factor (TRF) Myb_DNA-binding PF00249.31 KXH40364.1 - 2.1e-05 24.6 0.0 4.2e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KXH40364.1 - 0.06 13.6 0.0 0.14 12.5 0.0 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain PSK_trans_fac PF07704.11 KXH40364.1 - 0.19 12.5 6.5 4.9 8.0 0.2 3.3 2 0 0 2 2 2 0 Rv0623-like transcription factor Hydantoinase_B PF02538.14 KXH40365.1 - 1.5e-214 713.3 1.0 2.1e-214 712.7 1.0 1.2 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 KXH40365.1 - 2.3e-104 348.8 0.1 5.1e-104 347.6 0.1 1.6 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 KXH40365.1 - 4.6e-54 182.8 0.3 1.5e-50 171.4 0.0 3.3 2 1 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region Proteasome_A_N PF10584.9 KXH40365.1 - 0.044 13.5 0.1 0.084 12.6 0.1 1.5 1 0 0 1 1 1 0 Proteasome subunit A N-terminal signature Aminotran_1_2 PF00155.21 KXH40366.1 - 5.1e-70 236.4 0.0 5.8e-70 236.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 KXH40366.1 - 0.077 11.8 0.0 0.12 11.1 0.0 1.3 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase DHDPS PF00701.22 KXH40367.1 - 7.7e-48 162.7 0.0 9.3e-48 162.4 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family PEP_mutase PF13714.6 KXH40367.1 - 0.00031 20.3 0.0 0.0005 19.6 0.0 1.3 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Peripla_BP_1 PF00532.21 KXH40367.1 - 0.061 12.7 0.0 0.088 12.2 0.0 1.3 1 0 0 1 1 1 0 Periplasmic binding proteins and sugar binding domain of LacI family PucR PF07905.11 KXH40367.1 - 0.15 12.4 0.0 0.5 10.7 0.0 1.9 1 1 0 1 1 1 0 Purine catabolism regulatory protein-like family His_Phos_2 PF00328.22 KXH40368.1 - 1.1e-05 25.0 0.0 3.2e-05 23.5 0.0 1.7 1 1 1 2 2 2 1 Histidine phosphatase superfamily (branch 2) Clostridium_P47 PF06597.11 KXH40368.1 - 0.029 13.1 0.3 0.044 12.5 0.3 1.2 1 0 0 1 1 1 0 Clostridium P-47 protein DUF4342 PF14242.6 KXH40368.1 - 1.7 8.7 3.7 4 7.5 3.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4342) DASH_Dad1 PF08649.10 KXH40369.1 - 5.1e-27 93.8 3.8 6.4e-27 93.5 3.8 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad1 DASH_Dad4 PF08650.10 KXH40369.1 - 0.0033 17.4 0.8 0.0048 16.8 0.8 1.2 1 0 0 1 1 1 1 DASH complex subunit Dad4 V_ATPase_I PF01496.19 KXH40369.1 - 0.39 8.6 3.4 0.38 8.6 3.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ras PF00071.22 KXH40371.1 - 7.2e-48 162.3 0.0 9.6e-48 161.8 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXH40371.1 - 5.3e-20 71.8 0.0 1e-19 70.9 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXH40371.1 - 5.8e-05 22.6 0.0 0.00011 21.7 0.0 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family AAA_7 PF12775.7 KXH40371.1 - 0.08 12.4 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Skp1_POZ PF03931.15 KXH40372.1 - 7.7e-09 35.6 0.0 1e-08 35.2 0.0 1.2 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain DBR1 PF05011.13 KXH40373.1 - 7.4e-46 156.0 0.2 7.4e-46 156.0 0.2 2.2 1 1 1 2 2 2 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.28 KXH40373.1 - 9.8e-06 26.2 0.1 1.9e-05 25.3 0.1 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF2486 PF10667.9 KXH40373.1 - 0.09 13.0 17.6 0.17 12.1 17.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2486) LSM PF01423.22 KXH40374.1 - 5e-19 67.8 0.1 6.4e-19 67.4 0.1 1.1 1 0 0 1 1 1 1 LSM domain PRMT5_TIM PF17285.2 KXH40375.1 - 6.4e-72 241.8 0.0 8.9e-72 241.4 0.0 1.2 1 0 0 1 1 1 1 PRMT5 TIM barrel domain PRMT5 PF05185.16 KXH40375.1 - 2e-66 223.1 0.0 3.4e-66 222.4 0.0 1.4 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_C PF17286.2 KXH40375.1 - 1.2e-56 191.4 0.0 1.8e-56 190.8 0.0 1.3 1 0 0 1 1 1 1 PRMT5 oligomerisation domain Met_10 PF02475.16 KXH40375.1 - 0.068 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein OB_NTP_bind PF07717.16 KXH40376.1 - 1.8e-23 82.7 0.1 1.4e-22 79.8 0.0 2.5 3 0 0 3 3 3 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 KXH40376.1 - 5.7e-18 65.2 0.0 1.7e-17 63.7 0.0 1.9 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KXH40376.1 - 4.5e-11 43.1 0.0 2e-10 41.0 0.0 2.1 3 0 0 3 3 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KXH40376.1 - 1.4e-08 34.7 0.1 2.6e-08 33.9 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KXH40376.1 - 4.1e-06 27.1 0.0 1.2e-05 25.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 KXH40376.1 - 7.5e-05 22.4 0.1 0.00028 20.6 0.1 1.8 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain T2SSE PF00437.20 KXH40376.1 - 0.00024 20.3 0.0 0.00045 19.4 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_30 PF13604.6 KXH40376.1 - 0.003 17.3 0.0 0.0052 16.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.14 KXH40376.1 - 0.011 15.6 0.2 0.026 14.5 0.2 1.6 1 0 0 1 1 1 0 Flavivirus DEAD domain ResIII PF04851.15 KXH40376.1 - 0.019 15.0 0.0 3.3 7.7 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit DUF2075 PF09848.9 KXH40376.1 - 0.064 12.5 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RsgA_GTPase PF03193.16 KXH40376.1 - 0.15 11.9 0.0 0.76 9.7 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase CBP_BcsO PF17037.5 KXH40424.1 - 0.22 11.7 0.0 0.26 11.4 0.0 1.1 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsO PAS_4 PF08448.10 KXH40425.1 - 0.0029 17.8 0.0 0.0099 16.1 0.0 1.9 2 0 0 2 2 2 1 PAS fold PAS_11 PF14598.6 KXH40425.1 - 0.085 13.0 0.0 0.25 11.5 0.0 1.7 2 0 0 2 2 2 0 PAS domain PAS PF00989.25 KXH40425.1 - 0.14 12.2 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 PAS fold NuDC PF16273.5 KXH40426.1 - 0.84 10.2 6.3 0.35 11.4 2.9 2.0 1 1 1 2 2 2 0 Nuclear distribution C domain Mlh1_C PF16413.5 KXH40427.1 - 3.3e-99 331.6 0.0 5e-99 331.0 0.0 1.3 1 0 0 1 1 1 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 KXH40427.1 - 2e-33 114.6 0.0 3.7e-33 113.7 0.0 1.5 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 KXH40427.1 - 2.3e-11 43.7 0.0 4.6e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KXH40427.1 - 7.6e-05 23.2 0.0 0.00017 22.1 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF202 PF02656.15 KXH40430.1 - 4.4e-17 62.3 6.7 2.2e-16 60.0 0.0 2.9 3 1 0 3 3 3 1 Domain of unknown function (DUF202) T4SS_CagC PF16943.5 KXH40430.1 - 0.025 14.8 1.5 0.042 14.0 0.4 1.9 2 1 0 2 2 2 0 Cag pathogenicity island, type IV secretory system DUF1345 PF07077.11 KXH40430.1 - 0.051 13.3 3.4 1.2 8.8 1.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1345) Oxidored_q3 PF00499.20 KXH40430.1 - 0.064 13.0 3.7 0.14 11.9 2.7 1.8 1 1 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 DUF1772 PF08592.11 KXH40430.1 - 0.096 13.0 4.2 4.1 7.7 4.2 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF1772) COX4_pro_2 PF07835.12 KXH40430.1 - 0.11 12.6 0.0 0.11 12.6 0.0 2.4 3 0 0 3 3 3 0 Bacterial aa3 type cytochrome c oxidase subunit IV DUF5305 PF17231.2 KXH40430.1 - 0.15 11.5 1.0 2.6 7.4 0.0 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF5305) DUF1461 PF07314.11 KXH40430.1 - 0.2 11.5 0.5 2 8.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1461) Lig_chan PF00060.26 KXH40430.1 - 0.47 10.3 1.7 3.6 7.4 0.0 2.4 2 1 0 2 2 2 0 Ligand-gated ion channel DUF2207 PF09972.9 KXH40430.1 - 0.78 8.4 1.9 1.2 7.8 1.9 1.5 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Arm PF00514.23 KXH40432.1 - 8.5e-06 25.6 3.5 0.0073 16.3 0.3 4.2 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat CNDH2_C PF16858.5 KXH40432.1 - 0.013 15.4 3.8 0.23 11.3 3.4 2.2 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term HEAT PF02985.22 KXH40432.1 - 0.03 14.6 0.4 0.52 10.7 0.0 3.5 3 0 0 3 3 3 0 HEAT repeat DNA_pol_phi PF04931.13 KXH40432.1 - 0.034 12.3 13.3 0.072 11.2 13.3 1.6 1 0 0 1 1 1 0 DNA polymerase phi Med25_SD1 PF11235.8 KXH40432.1 - 0.063 13.6 0.0 0.21 11.9 0.0 1.8 1 0 0 1 1 1 0 Mediator complex subunit 25 synapsin 1 RTP1_C1 PF10363.9 KXH40432.1 - 0.081 13.1 1.6 8.9 6.5 0.2 4.3 5 1 1 6 6 5 0 Required for nuclear transport of RNA pol II C-terminus 1 Oxidored_nitro PF00148.19 KXH40432.1 - 0.16 10.7 0.0 0.28 9.9 0.0 1.3 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase BUD22 PF09073.10 KXH40432.1 - 0.17 11.2 9.9 0.034 13.5 6.6 1.6 2 0 0 2 2 2 0 BUD22 BLOC1S3 PF15753.5 KXH40432.1 - 0.53 10.4 7.4 0.68 10.0 4.8 2.3 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 Cwf_Cwc_15 PF04889.12 KXH40432.1 - 0.84 9.3 11.3 1.6 8.4 11.3 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein HEAT_EZ PF13513.6 KXH40432.1 - 1.2 9.7 4.6 5.6 7.6 0.7 3.7 3 1 0 3 3 2 0 HEAT-like repeat Nop14 PF04147.12 KXH40432.1 - 3.7 5.6 14.3 6.3 4.9 14.3 1.3 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 KXH40432.1 - 3.9 6.8 13.2 6.4 6.1 13.2 1.2 1 0 0 1 1 1 0 SDA1 DnaJ PF00226.31 KXH40433.1 - 2.2e-13 50.1 3.9 7.6e-13 48.4 0.3 2.9 3 0 0 3 3 3 1 DnaJ domain VIR_N PF15912.5 KXH40433.1 - 2.9 7.4 6.2 3.7 7.1 6.2 1.3 1 0 0 1 1 1 0 Virilizer, N-terminal ALMT PF11744.8 KXH40433.1 - 7.6 5.2 7.0 10 4.8 7.0 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DEAD PF00270.29 KXH40434.1 - 1.8e-50 171.2 0.0 9.9e-50 168.7 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXH40434.1 - 2.9e-26 92.0 0.0 2.2e-23 82.7 0.0 2.4 2 0 0 2 2 2 2 Helicase conserved C-terminal domain DBP10CT PF08147.12 KXH40434.1 - 4.1e-22 78.2 1.7 4.1e-22 78.2 1.7 2.2 2 0 0 2 2 2 1 DBP10CT (NUC160) domain Glyco_hydro_cc PF11790.8 KXH40435.1 - 9.6e-28 97.3 0.0 1.2e-27 97.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core E1-E2_ATPase PF00122.20 KXH40436.1 - 4e-38 130.8 8.2 7.9e-29 100.4 0.0 3.7 2 1 0 3 3 3 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 KXH40436.1 - 4.9e-21 75.3 7.5 4.9e-21 75.3 7.5 2.7 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KXH40436.1 - 8.3e-19 68.7 0.0 1.7e-14 54.6 0.0 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KXH40436.1 - 1.1e-16 60.7 0.0 2.1e-16 59.7 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KXH40436.1 - 8.4e-15 54.2 2.1 1.1e-14 53.8 0.1 2.4 3 0 0 3 3 3 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KXH40436.1 - 6.4e-06 26.1 0.2 1.3e-05 25.0 0.2 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF2463 PF09591.10 KXH40436.1 - 0.14 12.0 5.7 0.039 13.8 0.6 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2463) CoA_binding_3 PF13727.6 KXH40436.1 - 0.74 9.8 3.7 0.81 9.7 1.3 2.3 2 0 0 2 2 2 0 CoA-binding domain DUF1768 PF08719.11 KXH40437.1 - 8.8e-51 172.3 0.2 1.1e-50 172.0 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Toxin_2 PF00451.19 KXH40438.1 - 0.76 10.1 3.8 1.6 9.1 3.8 1.5 1 0 0 1 1 1 0 Scorpion short toxin, BmKK2 Fst_toxin PF13955.6 KXH40480.1 - 0.84 9.6 0.1 0.84 9.6 0.1 2.0 2 0 0 2 2 2 0 Toxin Fst, type I toxin-antitoxin system p450 PF00067.22 KXH40481.1 - 6.4e-54 183.4 0.0 7.8e-54 183.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3632 PF12311.8 KXH40484.1 - 5.4e-36 124.6 1.2 7e-36 124.3 1.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Peptidase_S8 PF00082.22 KXH40485.1 - 2.9e-32 112.1 0.0 5.1e-32 111.3 0.0 1.4 1 0 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 KXH40485.1 - 2e-09 38.1 0.0 4.5e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 Fn3-like domain DUF4232 PF14016.6 KXH40485.1 - 0.0078 16.4 0.1 0.046 13.9 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF4232) MFS_1 PF07690.16 KXH40486.1 - 2.6e-14 52.9 48.8 5e-08 32.2 16.8 3.1 1 1 1 2 2 2 2 Major Facilitator Superfamily AMP-binding PF00501.28 KXH40487.1 - 3.4e-74 250.0 0.0 4.7e-74 249.5 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 KXH40487.1 - 1.3e-66 224.4 0.0 1.9e-66 223.8 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.25 KXH40487.1 - 2.1e-10 40.8 0.0 6.6e-10 39.2 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.21 KXH40487.1 - 1.3e-09 37.9 0.0 2.6e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXH40487.1 - 4.9e-08 32.3 0.0 1.1e-07 31.1 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family AMP-binding_C PF13193.6 KXH40487.1 - 0.00019 22.3 0.0 0.00064 20.7 0.0 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Polysacc_synt_2 PF02719.15 KXH40487.1 - 0.0023 17.1 0.0 0.011 14.8 0.0 1.9 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KXH40487.1 - 0.094 11.8 0.3 0.52 9.4 0.3 2.2 1 1 0 1 1 1 0 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 KXH40487.1 - 0.15 11.4 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Git3 PF11710.8 KXH40488.1 - 6.5e-17 62.0 8.4 6.5e-17 62.0 8.4 1.6 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.21 KXH40488.1 - 5.9e-05 22.5 9.3 5.9e-05 22.5 9.3 1.4 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) LptF_LptG PF03739.14 KXH40488.1 - 0.031 13.1 0.1 0.031 13.1 0.1 2.6 3 0 0 3 3 3 0 Lipopolysaccharide export system permease LptF/LptG GPR_Gpa2_C PF11970.8 KXH40488.1 - 0.048 13.7 0.0 0.17 12.0 0.0 2.0 1 0 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 C-term Dicty_CAR PF05462.11 KXH40488.1 - 0.61 9.2 15.5 0.024 13.8 7.4 2.3 3 0 0 3 3 3 0 Slime mold cyclic AMP receptor DUF4291 PF14124.6 KXH40489.1 - 1.1e-64 217.6 0.0 1.6e-64 217.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4291) ABC2_membrane PF01061.24 KXH40490.1 - 2.1e-78 262.5 57.3 1.6e-41 142.0 19.9 3.3 4 0 0 4 4 3 2 ABC-2 type transporter PDR_CDR PF06422.12 KXH40490.1 - 7.4e-30 102.7 5.9 1.9e-25 88.6 0.0 3.9 3 0 0 3 3 3 2 CDR ABC transporter ABC_tran PF00005.27 KXH40490.1 - 1.3e-27 97.0 0.1 1.7e-14 54.5 0.0 3.6 2 1 1 3 3 3 3 ABC transporter ABC_trans_N PF14510.6 KXH40490.1 - 2.8e-11 43.9 0.0 7.4e-11 42.5 0.0 1.8 1 0 0 1 1 1 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 KXH40490.1 - 2e-09 37.0 40.3 8.7e-07 28.4 13.0 2.5 3 0 0 3 3 2 2 ABC-2 family transporter protein AAA_16 PF13191.6 KXH40490.1 - 2e-06 28.3 0.4 0.0087 16.4 0.1 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 KXH40490.1 - 2.2e-06 28.0 0.0 0.06 13.6 0.1 2.8 2 1 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KXH40490.1 - 1e-05 25.5 0.1 0.00039 20.4 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 KXH40490.1 - 5.4e-05 22.9 0.5 0.34 10.7 0.2 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain cobW PF02492.19 KXH40490.1 - 0.00018 21.2 0.3 0.0026 17.4 0.4 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 KXH40490.1 - 0.00035 20.6 0.1 0.21 11.7 0.2 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_18 PF13238.6 KXH40490.1 - 0.00056 20.5 0.0 0.058 13.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KXH40490.1 - 0.0016 18.3 0.2 0.28 11.1 0.4 2.5 2 0 0 2 2 2 1 NACHT domain AAA_21 PF13304.6 KXH40490.1 - 0.0019 18.1 0.0 0.39 10.5 0.0 2.7 3 0 0 3 3 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_28 PF13521.6 KXH40490.1 - 0.002 18.4 0.0 0.047 13.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain Ploopntkinase3 PF18751.1 KXH40490.1 - 0.0029 17.5 0.1 0.73 9.7 0.0 2.3 2 0 0 2 2 2 1 P-loop Nucleotide Kinase3 AAA_33 PF13671.6 KXH40490.1 - 0.0032 17.6 0.0 0.057 13.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KXH40490.1 - 0.0038 17.6 0.8 4.4 7.6 0.3 2.5 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.19 KXH40490.1 - 0.0041 16.6 0.1 0.3 10.5 0.0 3.2 3 1 0 4 4 4 1 RecF/RecN/SMC N terminal domain NB-ARC PF00931.22 KXH40490.1 - 0.011 14.9 1.0 1.4 8.0 0.3 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA PF00004.29 KXH40490.1 - 0.013 16.0 0.0 3.4 8.1 0.1 2.8 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 KXH40490.1 - 0.013 15.9 0.1 0.27 11.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KXH40490.1 - 0.017 14.8 1.8 3.5 7.3 0.7 2.3 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 KXH40490.1 - 0.017 15.1 0.4 0.15 12.0 0.3 2.2 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 KXH40490.1 - 0.037 13.7 0.1 0.23 11.2 0.1 2.2 3 0 0 3 3 2 0 AAA domain DnaB_C PF03796.15 KXH40490.1 - 0.038 13.3 0.1 2.9 7.1 0.0 2.2 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain Zeta_toxin PF06414.12 KXH40490.1 - 0.062 12.6 0.4 0.63 9.3 0.4 2.1 2 0 0 2 2 2 0 Zeta toxin PduV-EutP PF10662.9 KXH40490.1 - 0.081 12.7 0.2 1.1 9.0 0.4 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation RecA PF00154.21 KXH40490.1 - 0.084 12.3 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 recA bacterial DNA recombination protein NTPase_1 PF03266.15 KXH40490.1 - 0.13 12.1 0.1 9.9 6.0 0.2 2.9 3 0 0 3 3 3 0 NTPase ATPase_2 PF01637.18 KXH40490.1 - 0.14 12.1 0.1 18 5.1 0.1 2.3 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea T2SSE PF00437.20 KXH40490.1 - 0.15 11.1 0.0 4.5 6.3 0.1 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_25 PF13481.6 KXH40490.1 - 0.21 11.1 0.1 2.9 7.4 0.1 2.4 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 KXH40490.1 - 0.22 10.8 1.0 8.6 5.6 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family Antimicrobial22 PF16047.5 KXH40490.1 - 0.99 9.3 3.8 3.3 7.6 0.2 2.7 2 0 0 2 2 2 0 Frog antimicrobial peptide Sugar_tr PF00083.24 KXH40491.1 - 7.4e-116 387.7 22.8 4.8e-115 385.0 22.8 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH40491.1 - 2.7e-28 98.9 37.2 4.6e-18 65.3 13.8 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily BT1 PF03092.16 KXH40491.1 - 0.00082 17.7 2.2 0.0013 17.0 0.7 2.0 1 1 1 2 2 2 1 BT1 family ACCA PF03255.14 KXH40491.1 - 0.12 12.2 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit PAN_4 PF14295.6 KXH40492.1 - 0.024 14.5 3.3 0.14 12.1 0.5 2.6 2 0 0 2 2 2 0 PAN domain Fungal_trans PF04082.18 KXH40493.1 - 1.1e-22 80.3 0.0 2.1e-22 79.4 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH40493.1 - 1.1e-05 25.5 11.4 2.3e-05 24.4 11.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LPMO_10 PF03067.15 KXH40494.1 - 1.4e-09 38.9 0.6 3e-09 37.8 0.6 1.5 1 1 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Spore_III_AF PF09581.10 KXH40495.1 - 0.12 12.4 3.8 0.21 11.6 3.8 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) Menin PF05053.13 KXH40495.1 - 8.6 4.6 12.9 11 4.2 12.9 1.2 1 0 0 1 1 1 0 Menin AAA PF00004.29 KXH40497.1 - 2.2e-16 60.5 0.0 3.8e-16 59.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KXH40497.1 - 3.4e-05 24.3 0.1 8.9e-05 22.9 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KXH40497.1 - 0.00043 20.6 0.2 0.0021 18.3 0.2 2.1 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KXH40497.1 - 0.003 17.6 0.0 0.0067 16.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KXH40497.1 - 0.014 15.1 0.0 0.026 14.3 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 KXH40497.1 - 0.14 12.3 0.0 0.28 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain RhoGAP PF00620.27 KXH40500.1 - 1.1e-44 151.9 0.3 4.1e-44 150.1 0.2 2.0 2 0 0 2 2 2 1 RhoGAP domain PH PF00169.29 KXH40500.1 - 1.4e-11 44.8 0.0 3.2e-11 43.6 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 KXH40500.1 - 0.013 15.8 0.1 0.23 11.8 0.0 2.4 2 0 0 2 2 2 0 Pleckstrin homology domain PX PF00787.24 KXH40500.1 - 0.037 14.0 0.0 0.11 12.5 0.0 1.8 1 0 0 1 1 1 0 PX domain Pyr_redox_2 PF07992.14 KXH40507.1 - 3.5e-36 124.9 0.0 1.5e-35 122.9 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXH40507.1 - 3.8e-12 46.6 0.0 1e-09 38.8 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXH40507.1 - 7.7e-05 22.7 0.0 3.2 7.7 0.0 3.6 3 1 1 4 4 4 2 FAD-NAD(P)-binding K_oxygenase PF13434.6 KXH40507.1 - 0.0032 16.7 0.0 0.0098 15.1 0.0 1.7 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.12 KXH40507.1 - 0.0082 15.2 0.0 1.9 7.4 0.0 2.4 2 1 0 2 2 2 2 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KXH40507.1 - 0.017 14.4 0.0 0.025 13.9 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase End3 PF12761.7 KXH40508.1 - 1.9e-75 253.4 0.3 2.5e-75 253.1 0.3 1.1 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_4 PF12763.7 KXH40508.1 - 5.3e-48 161.3 0.0 4.5e-47 158.3 0.0 2.1 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 KXH40508.1 - 3e-07 29.5 0.2 8.5e-07 28.1 0.2 1.8 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 KXH40508.1 - 2.9e-05 24.4 0.0 0.0001 22.6 0.0 2.0 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 KXH40508.1 - 0.00064 19.4 0.8 0.0028 17.5 0.2 2.4 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.6 KXH40508.1 - 0.00083 19.2 0.1 0.0016 18.2 0.1 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 KXH40508.1 - 0.03 13.8 2.1 0.062 12.8 0.1 2.5 2 0 0 2 2 2 0 EF hand CENP-F_leu_zip PF10473.9 KXH40508.1 - 0.072 13.1 3.6 7.6 6.6 0.0 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Bacillus_HBL PF05791.11 KXH40508.1 - 0.14 12.0 0.5 0.3 10.9 0.1 1.7 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) EthD PF07110.11 KXH40509.1 - 0.054 14.6 3.1 0.1 13.7 0.1 3.1 3 0 0 3 3 3 0 EthD domain DSPc PF00782.20 KXH40510.1 - 2.1e-09 37.3 0.0 4.7e-07 29.7 0.0 2.2 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 KXH40510.1 - 0.071 13.4 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 Rit1 DUSP-like domain Peptidase_M28 PF04389.17 KXH40511.1 - 1.5e-29 103.1 0.0 2.4e-29 102.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KXH40511.1 - 4.9e-08 32.9 0.1 5.3e-07 29.5 0.1 2.3 2 1 0 2 2 2 1 Peptidase family M20/M25/M40 DUF1295 PF06966.12 KXH40512.1 - 4.7e-16 59.0 0.1 6e-16 58.7 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ERG4_ERG24 PF01222.17 KXH40512.1 - 6.7e-07 28.4 0.2 1e-06 27.8 0.2 1.3 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Steroid_dh PF02544.16 KXH40512.1 - 0.011 15.8 0.0 0.016 15.1 0.0 1.3 1 0 0 1 1 1 0 3-oxo-5-alpha-steroid 4-dehydrogenase MlaE PF02405.16 KXH40512.1 - 0.012 15.3 0.2 0.038 13.7 0.1 1.9 1 1 0 1 1 1 0 Permease MlaE AFG1_ATPase PF03969.16 KXH40513.1 - 5e-96 321.7 0.0 6.1e-92 308.3 0.0 2.1 2 0 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.6 KXH40513.1 - 7.4e-05 23.2 0.5 0.13 12.7 0.0 3.0 2 1 1 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 KXH40513.1 - 0.00021 21.6 0.1 0.018 15.3 0.0 2.8 2 1 0 2 2 2 1 AAA domain Bac_DnaA PF00308.18 KXH40513.1 - 0.00022 21.1 0.2 0.42 10.4 0.1 2.6 2 1 0 2 2 2 2 Bacterial dnaA protein AAA_14 PF13173.6 KXH40513.1 - 0.002 18.1 0.0 0.0045 17.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KXH40513.1 - 0.012 15.6 0.0 0.024 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA PF00004.29 KXH40513.1 - 0.054 13.9 0.0 0.15 12.5 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 KXH40513.1 - 0.13 12.2 0.0 0.37 10.7 0.0 1.9 1 1 0 1 1 1 0 NACHT domain RNA_helicase PF00910.22 KXH40513.1 - 0.13 12.6 0.1 0.45 10.9 0.1 2.0 1 1 0 1 1 1 0 RNA helicase XRN_M PF17846.1 KXH40514.1 - 0.11 11.5 0.0 0.12 11.3 0.0 1.0 1 0 0 1 1 1 0 Xrn1 helical domain Metallophos PF00149.28 KXH40516.1 - 7.2e-33 114.8 0.1 7.6e-23 82.1 0.0 2.1 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KXH40516.1 - 0.034 14.6 0.1 0.087 13.3 0.1 1.7 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain COA2 PF17051.5 KXH40517.1 - 0.00019 21.4 0.0 0.00028 20.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome C oxidase assembly factor 2 Secretin_N_2 PF07655.13 KXH40518.1 - 0.037 14.6 5.8 0.062 13.8 5.8 1.5 1 0 0 1 1 1 0 Secretin N-terminal domain LAP1C PF05609.12 KXH40518.1 - 0.11 11.6 14.1 0.13 11.3 14.1 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) FAM76 PF16046.5 KXH40518.1 - 0.68 9.2 15.2 1.1 8.6 15.2 1.3 1 0 0 1 1 1 0 FAM76 protein Raftlin PF15250.6 KXH40518.1 - 1.2 7.8 11.7 1.6 7.4 11.7 1.3 1 0 0 1 1 1 0 Raftlin DUF966 PF06136.13 KXH40518.1 - 1.7 8.3 11.7 2.2 7.9 11.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Apis_Csd PF11671.8 KXH40518.1 - 2.2 8.3 9.2 4 7.4 9.2 1.4 1 0 0 1 1 1 0 Complementary sex determiner protein Utp14 PF04615.13 KXH40518.1 - 3.6 6.1 30.2 4.4 5.7 30.2 1.0 1 0 0 1 1 1 0 Utp14 protein Cyclin_N PF00134.23 KXH40521.1 - 1.7e-05 24.6 0.0 0.00019 21.2 0.0 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain Putative_PNPOx PF01243.20 KXH40522.1 - 1.4e-21 76.5 0.0 2.2e-21 75.8 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase PNP_phzG_C PF10590.9 KXH40522.1 - 5.5e-20 71.2 1.6 5.5e-20 71.2 1.6 2.3 3 0 0 3 3 3 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxase_2 PF12766.7 KXH40522.1 - 0.00041 20.9 0.1 0.0011 19.5 0.1 1.8 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase CPSase_L_D2 PF02786.17 KXH40523.1 - 1.5e-112 374.3 0.2 6.1e-84 280.7 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.22 KXH40523.1 - 2.1e-46 156.9 0.0 5.4e-46 155.6 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 KXH40523.1 - 8.5e-46 156.1 0.0 2e-45 154.9 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase class-I OTCace_N PF02729.21 KXH40523.1 - 1.2e-44 151.9 0.0 2.7e-44 150.8 0.0 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_D3 PF02787.19 KXH40523.1 - 8.2e-41 139.2 0.1 2e-40 138.0 0.1 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace PF00185.24 KXH40523.1 - 6.7e-29 101.0 0.0 1.7e-28 99.7 0.0 1.7 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain MGS PF02142.22 KXH40523.1 - 2.1e-21 75.9 0.0 9.1e-21 73.9 0.0 2.2 2 0 0 2 2 2 1 MGS-like domain Dala_Dala_lig_C PF07478.13 KXH40523.1 - 8.3e-18 64.7 0.4 2.5e-08 33.7 0.1 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KXH40523.1 - 3e-16 59.4 0.1 5.8e-08 32.5 0.1 2.4 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 KXH40523.1 - 1.4e-09 37.8 0.0 0.00011 22.0 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Peptidase_C26 PF07722.13 KXH40523.1 - 1.2e-05 25.2 0.8 0.001 18.9 0.1 3.0 2 1 0 2 2 2 1 Peptidase C26 ATP-grasp_3 PF02655.14 KXH40523.1 - 1.7e-05 24.9 0.4 0.054 13.5 0.1 2.8 2 0 0 2 2 2 2 ATP-grasp domain DJ-1_PfpI PF01965.24 KXH40523.1 - 6.1e-05 22.9 0.1 0.068 13.0 0.0 3.7 3 0 0 3 3 3 1 DJ-1/PfpI family GARS_A PF01071.19 KXH40523.1 - 0.0028 17.5 0.4 2.2 8.0 0.0 3.0 3 0 0 3 3 3 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain CENP-B_dimeris PF09026.10 KXH40524.1 - 7 7.1 17.4 1 9.8 6.6 2.6 2 0 0 2 2 2 0 Centromere protein B dimerisation domain NB PF04159.13 KXH40525.1 - 0.04 14.0 0.0 0.043 13.8 0.0 1.0 1 0 0 1 1 1 0 NB glycoprotein DUF1899 PF08953.11 KXH40525.1 - 0.1 12.5 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1899) HicA_toxin PF07927.12 KXH40526.1 - 5.4e-07 29.5 0.0 1.5e-06 28.1 0.0 1.8 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, Ribonucleas_3_2 PF11469.8 KXH40526.1 - 0.04 14.3 0.0 0.086 13.3 0.0 1.5 1 0 0 1 1 1 0 Ribonuclease III Myb_DNA-bind_2 PF08914.11 KXH40526.1 - 0.066 13.4 0.1 0.21 11.8 0.1 1.8 1 0 0 1 1 1 0 Rap1 Myb domain Alliinase_C PF04864.13 KXH40527.1 - 0.083 11.8 0.2 0.14 11.0 0.2 1.2 1 0 0 1 1 1 0 Allinase TAP42 PF04177.12 KXH40528.1 - 2.5e-105 352.1 0.1 2.8e-105 352.0 0.1 1.0 1 0 0 1 1 1 1 TAP42-like family ELM2 PF01448.24 KXH40528.1 - 0.013 16.2 0.6 0.047 14.5 0.0 2.1 2 0 0 2 2 2 0 ELM2 domain Ribonuclease_3 PF00636.26 KXH40529.1 - 1.9e-44 150.6 0.1 1.7e-22 80.0 0.0 3.1 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KXH40529.1 - 1.7e-22 80.0 0.1 2.4e-08 34.2 0.0 3.7 3 0 0 3 3 3 3 Ribonuclease-III-like Dicer_dimer PF03368.14 KXH40529.1 - 3.6e-22 78.3 0.2 8.8e-20 70.7 0.1 3.4 3 0 0 3 3 3 1 Dicer dimerisation domain Helicase_C PF00271.31 KXH40529.1 - 8.6e-18 64.7 0.0 2.4e-17 63.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXH40529.1 - 8.7e-18 64.9 0.3 1e-16 61.4 0.2 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KXH40529.1 - 3.1e-11 43.4 0.0 1.2e-10 41.4 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Flavi_DEAD PF07652.14 KXH40529.1 - 0.0039 17.2 0.6 0.031 14.3 0.1 2.5 2 0 0 2 2 2 1 Flavivirus DEAD domain ERCC3_RAD25_C PF16203.5 KXH40529.1 - 0.029 13.6 0.0 0.059 12.6 0.0 1.4 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase AAA_22 PF13401.6 KXH40529.1 - 0.11 12.7 0.0 0.44 10.8 0.0 2.0 1 1 0 1 1 1 0 AAA domain MTHFR PF02219.17 KXH40530.1 - 2.7e-111 371.5 0.0 4.2e-111 370.9 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase DUF3425 PF11905.8 KXH40531.1 - 6.5e-13 48.8 1.1 2.2e-12 47.1 1.1 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_2 PF07716.15 KXH40531.1 - 0.19 11.9 6.4 0.34 11.0 6.4 1.3 1 0 0 1 1 1 0 Basic region leucine zipper Homeobox_KN PF05920.11 KXH40532.1 - 4.1e-16 58.6 1.4 4.1e-16 58.6 1.4 3.2 4 0 0 4 4 4 1 Homeobox KN domain HTH_Tnp_Tc5 PF03221.16 KXH40532.1 - 3.3e-15 55.8 0.2 8e-05 22.6 0.1 5.2 5 0 0 5 5 5 3 Tc5 transposase DNA-binding domain Homeodomain PF00046.29 KXH40532.1 - 7e-06 25.8 0.6 2.1e-05 24.3 0.6 1.8 1 0 0 1 1 1 1 Homeodomain zf-C2H2 PF00096.26 KXH40532.1 - 0.00017 21.9 15.9 0.026 14.9 3.8 4.2 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXH40532.1 - 0.004 17.9 3.9 0.004 17.9 3.9 4.8 5 0 0 5 5 5 1 C2H2-type zinc finger Elf1 PF05129.13 KXH40532.1 - 3.4 7.8 5.9 5.4 7.1 4.2 2.2 2 1 1 3 3 3 0 Transcription elongation factor Elf1 like Patatin PF01734.22 KXH40533.1 - 3e-24 86.3 0.0 4.5e-24 85.8 0.0 1.3 1 0 0 1 1 1 1 Patatin-like phospholipase Tetraspanin PF00335.20 KXH40534.1 - 0.02 14.6 0.0 0.039 13.7 0.0 1.5 1 1 0 1 1 1 0 Tetraspanin family RskA PF10099.9 KXH40534.1 - 0.021 15.2 1.3 0.029 14.7 1.3 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Tic110 PF16940.5 KXH40534.1 - 0.28 9.6 1.9 0.34 9.4 1.9 1.0 1 0 0 1 1 1 0 Chloroplast envelope transporter Gly-zipper_OmpA PF13436.6 KXH40535.1 - 0.11 12.3 29.9 0.49 10.2 29.7 2.2 1 1 1 2 2 2 0 Glycine-zipper domain Gly-zipper_YMGG PF13441.6 KXH40535.1 - 0.75 9.6 25.5 1.6 8.5 25.5 1.6 1 0 0 1 1 1 0 YMGG-like Gly-zipper MFS_1 PF07690.16 KXH40537.1 - 7.7e-23 81.0 24.2 7.7e-23 81.0 24.2 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily 4HBT PF03061.22 KXH40538.1 - 3e-07 30.7 0.1 4.7e-07 30.1 0.1 1.3 1 0 0 1 1 1 1 Thioesterase superfamily PS-DH PF14765.6 KXH40538.1 - 0.099 11.9 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Polyketide synthase dehydratase rRNA_processing PF08524.11 KXH40539.1 - 0.0013 18.8 12.3 0.27 11.2 8.5 2.4 2 0 0 2 2 2 2 rRNA processing Hamartin PF04388.12 KXH40539.1 - 0.16 10.6 13.2 0.2 10.3 13.2 1.1 1 0 0 1 1 1 0 Hamartin protein RhoGAP PF00620.27 KXH40540.1 - 5.3e-45 153.0 0.0 5.3e-45 153.0 0.0 2.7 3 2 1 4 4 4 1 RhoGAP domain LIM PF00412.22 KXH40540.1 - 6.1e-13 48.8 16.2 6.2e-07 29.5 0.1 3.3 3 0 0 3 3 3 2 LIM domain DUF4407 PF14362.6 KXH40540.1 - 0.3 10.4 4.8 0.59 9.4 4.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TMF_TATA_bd PF12325.8 KXH40540.1 - 0.76 10.0 9.2 0.082 13.1 1.2 3.1 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding Fez1 PF06818.15 KXH40540.1 - 0.76 10.2 12.5 2.2 8.7 12.5 1.7 1 0 0 1 1 1 0 Fez1 SlyX PF04102.12 KXH40540.1 - 2.2 9.0 11.0 0.11 13.2 0.8 3.5 3 1 0 3 3 3 0 SlyX Desulfoferrod_N PF06397.12 KXH40540.1 - 2.9 7.6 6.5 12 5.6 0.8 3.0 2 1 1 3 3 3 0 Desulfoferrodoxin, N-terminal domain Zn-ribbon_8 PF09723.10 KXH40540.1 - 4.9 7.3 17.4 1.1 9.4 1.2 4.4 4 0 0 4 4 4 0 Zinc ribbon domain PRKG1_interact PF15898.5 KXH40540.1 - 5.1 8.1 10.3 49 4.9 0.2 3.3 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain IFT20 PF14931.6 KXH40540.1 - 7.4 6.8 11.8 0.3 11.3 3.2 2.4 2 0 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 CLASP_N PF12348.8 KXH40541.1 - 9.7e-136 450.6 0.0 5.7e-88 294.3 0.0 2.7 3 0 0 3 3 3 2 CLASP N terminal HEAT PF02985.22 KXH40541.1 - 3.3e-05 23.8 0.0 11 6.6 0.0 5.2 5 0 0 5 5 5 2 HEAT repeat Cnd1 PF12717.7 KXH40541.1 - 0.016 15.3 0.1 2.5 8.1 0.0 3.3 3 1 1 4 4 4 0 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 KXH40541.1 - 0.23 10.0 0.0 1.1 7.7 0.0 2.3 3 0 0 3 3 3 0 Adaptin N terminal region BSP PF04450.12 KXH40542.1 - 1.3e-77 260.3 0.0 1.5e-77 260.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase of plants and bacteria FtsJ PF01728.19 KXH40545.1 - 1.3e-32 113.3 3.8 3.7e-32 111.8 3.8 1.7 1 1 0 1 1 1 1 FtsJ-like methyltransferase DUF4638 PF15472.6 KXH40545.1 - 0.097 12.4 1.3 8.1 6.1 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4638) CCDC144C PF14915.6 KXH40546.1 - 0.0022 17.2 23.2 0.0022 17.2 23.2 3.3 1 1 2 3 3 3 3 CCDC144C protein coiled-coil region AT_hook PF02178.19 KXH40546.1 - 5.8 7.1 11.3 0.43 10.6 3.4 3.0 2 0 0 2 2 2 0 AT hook motif OST3_OST6 PF04756.13 KXH40547.1 - 3.6e-111 371.2 0.0 4.1e-111 371.0 0.0 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family HXXEE PF13787.6 KXH40547.1 - 0.11 13.4 0.3 0.11 13.4 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function with HXXEE motif Pex14_N PF04695.13 KXH40547.1 - 0.22 12.2 0.2 0.43 11.2 0.2 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region MerC PF03203.14 KXH40547.1 - 0.23 11.9 5.9 1.7 9.1 0.1 2.6 2 0 0 2 2 2 0 MerC mercury resistance protein DUF3169 PF11368.8 KXH40547.1 - 0.95 8.9 3.4 4.2 6.8 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) Glyco_hydro_6 PF01341.17 KXH40548.1 - 5.3e-98 328.5 0.1 7e-98 328.1 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 WD40 PF00400.32 KXH40549.1 - 3.6e-40 135.2 18.3 1.2e-08 35.5 0.2 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXH40549.1 - 6.1e-09 36.1 0.4 0.09 13.1 0.0 4.2 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KXH40549.1 - 6.2e-05 21.8 4.4 0.088 11.4 0.1 4.0 2 1 1 4 4 4 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KXH40549.1 - 0.0029 16.6 0.1 8.9 5.2 0.0 3.8 2 2 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KXH40549.1 - 0.009 15.4 0.0 0.51 9.6 0.0 2.2 2 0 0 2 2 2 1 WD40-like domain PD40 PF07676.12 KXH40549.1 - 0.018 14.9 0.4 23 5.1 0.0 4.4 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat TAF8_C PF10406.9 KXH40550.1 - 6.2e-17 61.9 0.2 6.2e-17 61.9 0.2 2.2 2 0 0 2 2 2 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP PF07524.13 KXH40550.1 - 9.2e-05 22.4 0.0 0.00018 21.5 0.0 1.5 1 1 0 1 1 1 1 Bromodomain associated Pkinase_Tyr PF07714.17 KXH40551.1 - 6.6e-15 55.1 0.0 5.4e-13 48.8 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase LRR_8 PF13855.6 KXH40551.1 - 6.4e-14 51.5 1.7 2.3e-06 27.3 0.2 4.6 3 1 1 4 4 4 3 Leucine rich repeat Pkinase PF00069.25 KXH40551.1 - 3e-13 49.7 0.0 1.4e-12 47.6 0.0 1.8 1 1 1 2 2 2 1 Protein kinase domain LRR_4 PF12799.7 KXH40551.1 - 3.9e-07 30.3 2.2 0.83 10.2 0.3 5.2 3 1 3 6 6 6 2 Leucine Rich repeats (2 copies) Kdo PF06293.14 KXH40551.1 - 1.7e-05 24.3 0.0 2.9e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family LRR_9 PF14580.6 KXH40551.1 - 0.005 16.3 0.0 4.2 6.8 0.1 3.0 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 KXH40551.1 - 0.029 14.9 5.4 67 4.6 0.0 5.8 3 2 0 3 3 3 0 Leucine Rich Repeat APH PF01636.23 KXH40551.1 - 0.13 12.2 0.3 0.24 11.3 0.3 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family DUF2415 PF10313.9 KXH40552.1 - 0.00071 19.4 0.0 0.0019 18.1 0.0 1.7 1 0 0 1 1 1 1 Uncharacterised protein domain (DUF2415) WD40 PF00400.32 KXH40552.1 - 0.027 15.3 1.6 0.33 11.9 0.4 3.3 3 0 0 3 3 3 0 WD domain, G-beta repeat RXT2_N PF08595.11 KXH40552.1 - 2.1 8.3 5.5 4.8 7.2 5.2 1.7 1 1 0 1 1 1 0 RXT2-like, N-terminal Amidase PF01425.21 KXH40553.1 - 8.5e-89 298.6 0.0 1.5e-88 297.7 0.0 1.4 1 0 0 1 1 1 1 Amidase CT_A_B PF02626.15 KXH40553.1 - 1.8e-86 290.1 0.0 3.1e-86 289.3 0.0 1.4 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain A and B CPSase_L_D2 PF02786.17 KXH40553.1 - 2.4e-66 223.2 0.2 4e-66 222.5 0.2 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 KXH40553.1 - 1.2e-39 135.2 0.4 3e-39 134.0 0.1 1.9 2 0 0 2 2 1 1 Biotin carboxylase, N-terminal domain CT_C_D PF02682.16 KXH40553.1 - 8.4e-38 130.1 0.0 1.8e-37 129.1 0.0 1.5 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain C and D Biotin_carb_C PF02785.19 KXH40553.1 - 1.1e-32 112.3 0.0 2.6e-32 111.1 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Dala_Dala_lig_C PF07478.13 KXH40553.1 - 2.9e-12 46.5 0.0 5.3e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl PF00364.22 KXH40553.1 - 7.4e-11 41.7 1.4 1.8e-10 40.5 1.4 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp PF02222.22 KXH40553.1 - 1.5e-05 24.7 0.0 6.7e-05 22.5 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 KXH40553.1 - 8e-05 22.4 0.0 0.63 9.9 0.2 2.9 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp_3 PF02655.14 KXH40553.1 - 0.0016 18.5 0.0 0.0031 17.6 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.6 KXH40553.1 - 0.059 13.1 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_5 PF13549.6 KXH40553.1 - 0.062 12.7 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain GCV_H PF01597.19 KXH40553.1 - 0.08 12.8 0.1 0.18 11.7 0.1 1.5 1 0 0 1 1 1 0 Glycine cleavage H-protein C2 PF00168.30 KXH40555.1 - 1.1e-27 96.3 0.0 4.4e-15 55.8 0.0 2.5 2 0 0 2 2 2 2 C2 domain Sporozoite_P67 PF05642.11 KXH40555.1 - 6.5 4.7 13.6 0.018 13.2 3.1 1.8 2 0 0 2 2 2 0 Sporozoite P67 surface antigen Oxidored_FMN PF00724.20 KXH40556.1 - 3.2e-55 187.8 0.0 3.6e-55 187.6 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.17 KXH40556.1 - 0.0063 15.6 0.0 0.11 11.6 0.0 2.1 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) DUF1611_N PF17396.2 KXH40556.1 - 0.17 12.1 0.0 17 5.7 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1611_N) Rossmann-like domain Glyco_hydro_76 PF03663.14 KXH40557.1 - 3.2e-121 405.3 11.5 3.7e-121 405.1 11.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 DEAD PF00270.29 KXH40558.1 - 3.7e-32 111.5 0.1 5.6e-32 110.9 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXH40558.1 - 1.7e-24 86.3 0.0 6e-23 81.3 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 KXH40558.1 - 0.035 14.4 0.0 0.08 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain CMS1 PF14617.6 KXH40558.1 - 0.053 12.8 0.0 0.091 12.1 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Fungal_trans_2 PF11951.8 KXH40560.1 - 1e-19 70.6 0.2 1.5e-10 40.5 0.0 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH40560.1 - 0.0023 18.0 16.8 0.0023 18.0 16.8 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Amino_oxidase PF01593.24 KXH40561.1 - 6.3e-25 88.4 0.0 8.9e-25 87.9 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.24 KXH40561.1 - 0.01 15.4 0.0 0.014 15.0 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.17 KXH40561.1 - 0.013 14.7 0.1 0.023 14.0 0.1 1.3 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.24 KXH40561.1 - 0.16 11.0 2.4 0.3 10.1 2.4 1.4 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.7 KXH40561.1 - 1.1 8.5 3.5 6.2 6.1 2.8 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase AA_permease_2 PF13520.6 KXH40562.1 - 1.8e-39 135.8 43.5 1.3e-38 133.0 43.5 1.9 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXH40562.1 - 1.9e-19 69.6 33.4 2e-16 59.7 14.3 2.0 2 0 0 2 2 2 2 Amino acid permease Sugar_tr PF00083.24 KXH40563.1 - 1.4e-85 287.9 20.1 1.7e-85 287.6 20.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH40563.1 - 3.9e-19 68.8 45.2 1.5e-17 63.5 26.1 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4880 PF16220.5 KXH40563.1 - 0.096 12.6 0.4 0.28 11.1 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4880) Sulfotransfer_4 PF17784.1 KXH40564.1 - 2.1e-55 187.9 0.0 2.4e-55 187.7 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KXH40564.1 - 0.00041 20.8 0.2 0.006 17.0 0.2 2.3 1 1 0 1 1 1 1 Sulfotransferase family Aspzincin_M35 PF14521.6 KXH40565.1 - 5.7e-05 23.7 0.4 2.4 8.7 0.0 3.9 2 1 1 3 3 3 3 Lysine-specific metallo-endopeptidase TMEM51 PF15345.6 KXH40565.1 - 0.0052 16.7 0.1 0.0052 16.7 0.1 1.7 2 0 0 2 2 2 1 Transmembrane protein 51 HRXXH PF13933.6 KXH40565.1 - 0.016 14.8 0.0 0.062 12.9 0.1 1.9 2 0 0 2 2 2 0 Putative peptidase family Alpha-L-AF_C PF06964.12 KXH40566.1 - 3.5e-20 72.8 0.0 7.5e-20 71.7 0.0 1.5 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain Peptidase_S8 PF00082.22 KXH40567.1 - 5.1e-55 186.8 3.3 7.4e-55 186.3 3.3 1.2 1 0 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 KXH40567.1 - 3.7e-10 40.5 0.0 1.7e-09 38.4 0.0 2.2 2 0 0 2 2 2 1 Fn3-like domain Fungal_trans PF04082.18 KXH40568.1 - 2.5e-18 66.1 0.0 3.8e-18 65.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH40568.1 - 4.3e-08 33.2 11.6 6.6e-08 32.6 11.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pox_A_type_inc PF04508.12 KXH40568.1 - 0.067 13.1 5.0 0.13 12.2 5.0 1.5 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat DJ-1_PfpI PF01965.24 KXH40569.1 - 2.9e-06 27.2 0.0 0.0002 21.2 0.0 2.6 1 1 0 1 1 1 1 DJ-1/PfpI family Oxidored_FMN PF00724.20 KXH40570.1 - 1.1e-87 294.5 0.0 1.3e-87 294.3 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family ABC2_membrane PF01061.24 KXH40571.1 - 1.8e-77 259.5 63.4 3e-43 147.7 20.4 2.7 3 0 0 3 3 3 2 ABC-2 type transporter PDR_CDR PF06422.12 KXH40571.1 - 3.2e-35 119.9 2.5 1.5e-28 98.5 0.0 3.2 2 0 0 2 2 2 2 CDR ABC transporter ABC_tran PF00005.27 KXH40571.1 - 3.8e-34 118.1 2.8 3e-16 60.2 0.0 3.4 4 0 0 4 4 3 2 ABC transporter ABC_trans_N PF14510.6 KXH40571.1 - 6.3e-14 52.4 0.6 3.9e-13 49.8 0.6 2.5 1 0 0 1 1 1 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 KXH40571.1 - 1.5e-13 50.6 36.5 4.1e-10 39.3 10.5 2.5 2 0 0 2 2 2 2 ABC-2 family transporter protein RsgA_GTPase PF03193.16 KXH40571.1 - 7.9e-06 25.9 0.0 2.8e-05 24.1 0.0 1.8 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 KXH40571.1 - 9.1e-06 25.4 0.1 0.0021 17.7 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KXH40571.1 - 1.8e-05 24.4 0.0 0.011 15.5 0.1 2.9 3 0 0 3 3 2 1 P-loop containing region of AAA domain AAA_21 PF13304.6 KXH40571.1 - 9e-05 22.4 1.4 0.22 11.3 0.1 3.1 2 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KXH40571.1 - 0.00014 22.3 2.9 0.006 17.0 0.1 2.8 3 0 0 3 3 2 1 AAA ATPase domain AAA_33 PF13671.6 KXH40571.1 - 0.00017 21.8 1.3 0.13 12.4 0.0 3.3 3 0 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.23 KXH40571.1 - 0.00033 20.7 0.0 0.15 12.2 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.6 KXH40571.1 - 0.00056 20.2 0.3 0.069 13.4 0.1 2.8 2 1 0 2 2 2 1 AAA domain NACHT PF05729.12 KXH40571.1 - 0.0012 18.8 0.0 0.065 13.2 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_30 PF13604.6 KXH40571.1 - 0.0049 16.6 0.0 0.4 10.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KXH40571.1 - 0.0073 16.9 0.0 0.062 13.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 KXH40571.1 - 0.0082 16.7 0.4 0.0082 16.7 0.4 3.3 4 1 0 4 4 3 1 AAA domain AAA_28 PF13521.6 KXH40571.1 - 0.011 16.0 0.1 0.011 16.0 0.1 2.4 3 0 0 3 3 1 0 AAA domain AAA_17 PF13207.6 KXH40571.1 - 0.021 15.3 1.4 1.2 9.6 0.0 3.0 3 0 0 3 3 2 0 AAA domain cobW PF02492.19 KXH40571.1 - 0.024 14.2 0.5 0.57 9.8 0.2 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain T2SSE PF00437.20 KXH40571.1 - 0.028 13.5 0.0 4.3 6.3 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein dNK PF01712.19 KXH40571.1 - 0.032 14.1 0.0 0.094 12.6 0.0 1.7 2 0 0 2 2 1 0 Deoxynucleoside kinase FtsK_SpoIIIE PF01580.18 KXH40571.1 - 0.033 13.5 0.1 8 5.7 0.1 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA PF00004.29 KXH40571.1 - 0.046 14.1 0.1 2.6 8.5 0.0 3.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KXH40571.1 - 0.053 13.9 0.0 3.8 7.9 0.0 2.6 2 0 0 2 2 2 0 RNA helicase TsaE PF02367.17 KXH40571.1 - 0.069 13.1 0.3 0.28 11.2 0.2 1.9 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Aldolase_II PF00596.21 KXH40572.1 - 3.5e-49 167.3 0.2 4.9e-49 166.8 0.2 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain CTP_transf_1 PF01148.20 KXH40573.1 - 1.1e-78 264.7 23.9 1.4e-78 264.3 23.9 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family DUF3636 PF12331.8 KXH40574.1 - 2.6e-40 137.6 0.3 5.5e-40 136.6 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3636) TMF_TATA_bd PF12325.8 KXH40574.1 - 0.39 11.0 5.6 0.75 10.0 5.6 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding ECH_1 PF00378.20 KXH40575.1 - 1.9e-15 56.9 0.0 3.1e-15 56.2 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Formyl_trans_C PF02911.18 KXH40575.1 - 1.5e-08 34.8 0.0 3.4e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain Glyco_hydro_28 PF00295.17 KXH40576.1 - 3.2e-47 161.2 1.7 1.8e-46 158.7 1.7 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 NPP1 PF05630.11 KXH40577.1 - 8.4e-60 202.2 1.1 9.6e-60 202.1 1.1 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) MCU PF04678.13 KXH40577.1 - 0.071 13.2 0.1 0.11 12.6 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial calcium uniporter BTB PF00651.31 KXH40578.1 - 0.0049 17.1 0.0 0.011 16.0 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Hce2 PF14856.6 KXH40579.1 - 1.1e-18 67.3 0.2 1.6e-18 66.9 0.2 1.2 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor DUF3012 PF11216.8 KXH40579.1 - 0.014 15.4 0.1 0.033 14.2 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3012) Abhydrolase_3 PF07859.13 KXH40580.1 - 1.2e-10 41.6 0.0 1.9e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Sulfate_transp PF00916.20 KXH40581.1 - 3.4e-79 266.3 10.0 5.3e-79 265.7 10.0 1.3 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KXH40581.1 - 3.3e-16 59.0 0.0 9.1e-16 57.6 0.0 1.7 2 0 0 2 2 2 1 STAS domain STAS_2 PF13466.6 KXH40581.1 - 0.00016 22.0 0.0 0.00052 20.3 0.0 2.0 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 KXH40581.1 - 0.00069 20.0 1.7 0.00069 20.0 1.7 2.5 2 0 0 2 2 2 1 Molybdate transporter of MFS superfamily Thiolase_N PF00108.23 KXH40582.1 - 1.4e-65 221.2 0.2 1.8e-65 220.9 0.2 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KXH40582.1 - 6.9e-40 135.5 0.2 1.5e-39 134.5 0.2 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain Glyco_hydro_cc PF11790.8 KXH40583.1 - 1.8e-71 240.5 0.5 2.1e-71 240.3 0.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Melibiase_2 PF16499.5 KXH40589.1 - 4.3e-61 206.6 4.8 1e-59 202.0 4.8 2.2 1 1 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 KXH40589.1 - 3.6e-12 46.2 0.6 6.3e-10 39.0 0.1 3.3 3 0 0 3 3 3 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 KXH40589.1 - 7.6e-08 31.7 0.0 1.4e-07 30.8 0.0 1.4 1 1 0 1 1 1 1 Melibiase Fungal_trans PF04082.18 KXH40590.1 - 4.9e-10 38.9 0.0 8.3e-10 38.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sugar_tr PF00083.24 KXH40591.1 - 4.6e-84 282.9 23.6 5.3e-84 282.7 23.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH40591.1 - 4.7e-18 65.2 35.7 8e-18 64.5 30.2 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_holin_2_4 PF16082.5 KXH40591.1 - 0.31 10.8 1.2 1.2 8.9 0.1 2.3 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like GH131_N PF18271.1 KXH40592.1 - 1.2e-79 267.6 0.5 1.4e-79 267.4 0.5 1.0 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain SIR2 PF02146.17 KXH40593.1 - 1.7e-31 109.5 0.0 1e-10 41.9 0.0 3.3 3 0 0 3 3 3 3 Sir2 family E1-E2_ATPase PF00122.20 KXH40595.1 - 3.2e-17 62.6 0.0 7.5e-17 61.4 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 KXH40595.1 - 2.6e-13 50.8 2.9 8.7e-08 32.7 2.3 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KXH40595.1 - 0.00053 20.0 1.9 0.00081 19.4 0.0 2.3 3 0 0 3 3 3 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KXH40595.1 - 0.026 14.3 0.1 0.29 10.8 0.1 2.4 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase DUF4059 PF13268.6 KXH40595.1 - 0.054 13.9 1.5 13 6.2 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4059) Uds1 PF15456.6 KXH40595.1 - 0.46 10.7 5.2 0.92 9.7 5.2 1.5 1 0 0 1 1 1 0 Up-regulated During Septation Ldh_1_C PF02866.18 KXH40596.1 - 1.4e-45 155.2 0.0 3.1e-45 154.1 0.0 1.6 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 KXH40596.1 - 1.6e-44 151.4 0.1 5.1e-44 149.8 0.0 1.8 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KXH40596.1 - 2.6e-05 23.4 0.0 3.9e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_hydro_4 PF02056.16 KXH40596.1 - 0.089 12.3 0.1 0.48 10.0 0.1 2.0 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase zf-C2HC5 PF06221.13 KXH40597.1 - 7.1e-22 77.1 5.9 1.1e-21 76.5 5.9 1.3 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type MIP-T3_C PF17749.1 KXH40597.1 - 0.038 13.9 1.0 0.093 12.7 1.0 1.6 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 C-terminal region Tropomodulin PF03250.14 KXH40597.1 - 0.061 13.4 0.9 0.13 12.3 0.9 1.5 1 0 0 1 1 1 0 Tropomodulin zf-ribbon_3 PF13248.6 KXH40597.1 - 0.11 12.0 1.8 2.8 7.5 0.2 2.5 2 0 0 2 2 2 0 zinc-ribbon domain FAM176 PF14851.6 KXH40597.1 - 0.69 9.6 4.1 1.5 8.5 4.1 1.6 1 0 0 1 1 1 0 FAM176 family Whi5 PF08528.11 KXH40598.1 - 2e-11 43.2 0.0 3.5e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 Whi5 like Rick_17kDa_Anti PF05433.15 KXH40599.1 - 3.8e-05 23.4 24.3 4.4e-05 23.3 16.1 2.5 2 0 0 2 2 2 2 Glycine zipper 2TM domain DUF2076 PF09849.9 KXH40599.1 - 0.00023 21.3 7.7 0.00023 21.3 7.7 2.1 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2076) Mito_fiss_reg PF05308.11 KXH40599.1 - 1.8 8.6 2.9 2.9 7.9 2.9 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator Glyco_hydro_3_C PF01915.22 KXH40600.1 - 5.6e-53 179.9 0.2 1.2e-51 175.6 0.1 2.3 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KXH40600.1 - 5.1e-44 150.9 0.0 8.9e-44 150.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KXH40600.1 - 1.3e-24 86.1 0.0 3.5e-24 84.7 0.0 1.8 1 0 0 1 1 1 1 Fibronectin type III-like domain Aminotran_5 PF00266.19 KXH40601.1 - 2e-17 63.2 0.0 3.1e-16 59.3 0.0 2.2 1 1 0 1 1 1 1 Aminotransferase class-V Asp PF00026.23 KXH40602.1 - 5.8e-63 213.2 8.3 7e-63 212.9 8.3 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KXH40602.1 - 2.4e-08 34.4 2.4 0.0023 18.2 0.3 3.2 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KXH40602.1 - 1.2e-05 25.9 2.3 0.014 16.0 0.8 2.9 2 1 0 2 2 2 2 Aspartyl protease SUKH-4 PF14435.6 KXH40602.1 - 0.051 13.6 0.0 0.085 12.9 0.0 1.3 1 0 0 1 1 1 0 SUKH-4 immunity protein gag-asp_proteas PF13975.6 KXH40602.1 - 0.23 12.1 3.0 1.2 9.7 0.7 2.8 2 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease ABC_tran PF00005.27 KXH40605.1 - 6.1e-36 123.9 0.0 6.8e-18 65.5 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KXH40605.1 - 5.9e-34 118.0 15.6 2.5e-23 83.1 3.1 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 KXH40605.1 - 5e-09 35.9 0.2 0.0016 17.9 0.0 3.3 3 0 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KXH40605.1 - 0.00015 21.7 3.3 0.14 11.9 0.1 4.0 3 1 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KXH40605.1 - 0.00097 19.6 0.1 0.087 13.2 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.22 KXH40605.1 - 0.0041 16.3 0.1 0.043 13.0 0.0 2.6 3 1 0 3 3 3 1 NB-ARC domain AAA_29 PF13555.6 KXH40605.1 - 0.0043 16.8 0.1 0.029 14.1 0.0 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA PF00004.29 KXH40605.1 - 0.015 15.8 0.6 0.2 12.1 0.1 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KXH40605.1 - 0.032 14.5 2.1 0.13 12.6 0.1 2.7 3 0 0 3 3 3 0 AAA domain RsgA_GTPase PF03193.16 KXH40605.1 - 0.042 13.8 0.0 0.18 11.7 0.0 1.9 2 0 0 2 2 2 0 RsgA GTPase AAA_23 PF13476.6 KXH40605.1 - 0.044 14.3 0.2 0.13 12.7 0.1 1.7 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 KXH40605.1 - 0.059 13.3 0.0 0.2 11.5 0.0 1.8 2 0 0 2 2 2 0 Rad17 P-loop domain MMR_HSR1 PF01926.23 KXH40605.1 - 0.11 12.6 0.0 1.1 9.4 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase ATPase_2 PF01637.18 KXH40605.1 - 0.11 12.4 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea T2SSE PF00437.20 KXH40605.1 - 0.12 11.4 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Piezo_RRas_bdg PF12166.8 KXH40605.1 - 0.12 11.6 0.4 0.21 10.8 0.4 1.3 1 0 0 1 1 1 0 Piezo non-specific cation channel, R-Ras-binding domain AAA_19 PF13245.6 KXH40605.1 - 0.15 12.4 0.0 1.1 9.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 KXH40605.1 - 0.19 11.4 0.1 1.8 8.2 0.1 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Ank_2 PF12796.7 KXH40606.1 - 2.8e-18 66.3 0.1 1e-05 26.0 0.0 4.1 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) AAA_16 PF13191.6 KXH40606.1 - 1.4e-12 48.3 0.9 5.1e-12 46.5 0.2 2.3 2 0 0 2 2 2 1 AAA ATPase domain Ank PF00023.30 KXH40606.1 - 3.2e-12 46.3 0.7 0.0011 19.4 0.0 4.8 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 KXH40606.1 - 4.9e-12 44.9 2.7 0.0017 18.7 0.0 5.8 5 1 0 5 5 4 2 Ankyrin repeat Ank_4 PF13637.6 KXH40606.1 - 2.1e-09 37.7 0.4 1.6e-05 25.3 0.1 4.1 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXH40606.1 - 1.1e-07 31.9 0.7 0.00053 20.2 0.0 3.4 2 2 1 3 3 3 3 Ankyrin repeats (many copies) AAA_22 PF13401.6 KXH40606.1 - 1.4e-07 31.9 0.1 4.9e-07 30.1 0.1 1.9 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 KXH40606.1 - 5e-06 26.5 0.8 2.2e-05 24.4 0.1 2.2 2 0 0 2 2 2 1 NACHT domain AAA_5 PF07728.14 KXH40606.1 - 1.9e-05 24.6 0.0 0.00023 21.2 0.0 2.5 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KXH40606.1 - 0.0015 18.7 0.0 0.017 15.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KXH40606.1 - 0.0016 18.9 0.0 0.0052 17.2 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 KXH40606.1 - 0.0042 16.8 0.0 0.15 11.8 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain NB-ARC PF00931.22 KXH40606.1 - 0.021 14.0 0.1 0.12 11.5 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_18 PF13238.6 KXH40606.1 - 0.027 15.0 0.0 0.93 10.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KXH40606.1 - 0.031 13.8 0.0 0.063 12.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 KXH40606.1 - 0.075 12.8 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein ABC_tran PF00005.27 KXH40606.1 - 0.19 12.3 0.0 1.2 9.7 0.0 2.2 2 1 0 2 2 2 0 ABC transporter Lactonase PF10282.9 KXH40607.1 - 1.4e-17 64.0 0.0 1.8e-17 63.6 0.0 1.2 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller DUF21 PF01595.20 KXH40608.1 - 1.1e-33 116.4 0.0 2e-33 115.5 0.0 1.4 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 KXH40608.1 - 0.0005 20.4 0.2 0.036 14.5 0.0 3.2 2 1 0 2 2 2 1 CBS domain 2-Hacid_dh_C PF02826.19 KXH40609.1 - 2.4e-52 176.9 0.1 4e-52 176.2 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KXH40609.1 - 2.3e-36 124.4 1.1 3.7e-36 123.7 0.5 1.6 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ACT PF01842.25 KXH40609.1 - 5.6e-05 22.8 0.3 0.00031 20.4 0.0 2.4 2 0 0 2 2 2 1 ACT domain XdhC_C PF13478.6 KXH40609.1 - 0.011 16.3 0.0 0.026 15.0 0.0 1.7 1 0 0 1 1 1 0 XdhC Rossmann domain ArfGap PF01412.18 KXH40610.1 - 5.2e-39 132.9 1.3 7.7e-39 132.4 1.3 1.2 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf partial_CstF PF15861.5 KXH40610.1 - 0.088 12.6 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Partial cleavage stimulation factor domain Synaptobrevin PF00957.21 KXH40611.1 - 0.0019 17.9 0.9 0.016 15.0 0.4 2.0 1 1 1 2 2 2 2 Synaptobrevin Peptidase_C27 PF05407.12 KXH40612.1 - 0.051 13.7 0.0 0.068 13.3 0.0 1.2 1 0 0 1 1 1 0 Rubella virus endopeptidase Ysc84 PF04366.12 KXH40613.1 - 3.6e-42 143.1 0.5 7.5e-42 142.1 0.5 1.5 1 0 0 1 1 1 1 Las17-binding protein actin regulator SH3_1 PF00018.28 KXH40613.1 - 1.5e-13 50.1 0.2 4.1e-13 48.7 0.0 1.8 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 KXH40613.1 - 3.8e-12 45.7 0.0 9.1e-12 44.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KXH40613.1 - 5.8e-11 42.1 0.0 1.2e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain DUF3104 PF11302.8 KXH40613.1 - 0.02 14.6 0.1 0.045 13.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3104) JmjC PF02373.22 KXH40699.1 - 4.4e-20 72.2 0.0 1.1e-19 71.0 0.0 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 KXH40699.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Cupin domain Sod_Cu PF00080.20 KXH40700.1 - 8.4e-09 35.7 0.1 1.2e-08 35.2 0.1 1.3 1 1 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Helo_like_N PF17111.5 KXH40701.1 - 9.7e-11 41.4 0.3 1.2e-10 41.1 0.3 1.3 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins SesA PF17107.5 KXH40701.1 - 4.1e-05 23.8 0.9 5.9e-05 23.2 0.8 1.4 1 1 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases Sec2p PF06428.11 KXH40701.1 - 0.014 15.4 3.0 1.4 8.9 0.6 2.3 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p SpmSyn_N PF17950.1 KXH40701.1 - 0.059 13.6 0.1 0.18 12.0 0.0 1.8 1 1 0 1 1 1 0 S-adenosylmethionine decarboxylase N -terminal P4Ha_N PF08336.11 KXH40701.1 - 0.13 12.3 0.4 0.93 9.5 0.1 2.0 1 1 1 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Peptidase_M43 PF05572.13 KXH40702.1 - 1.7e-12 47.5 0.1 3.4e-12 46.5 0.1 1.5 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 KXH40702.1 - 1.9e-05 24.9 0.4 3e-05 24.3 0.4 1.4 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 KXH40702.1 - 0.00019 21.4 0.4 0.00032 20.7 0.4 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 KXH40702.1 - 0.0002 21.9 0.1 0.00031 21.2 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KXH40702.1 - 0.00024 20.8 0.1 0.00097 18.8 0.1 1.9 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 KXH40702.1 - 0.0044 16.9 0.5 0.022 14.6 0.1 2.1 2 0 0 2 2 2 1 Matrixin DUF4953 PF16313.5 KXH40702.1 - 0.4 9.8 1.5 0.63 9.2 1.5 1.2 1 0 0 1 1 1 0 Met-zincin Peptidase_M57 PF12388.8 KXH40702.1 - 5.4 6.6 5.6 31 4.1 5.4 2.0 1 1 0 1 1 1 0 Dual-action HEIGH metallo-peptidase FAD_binding_4 PF01565.23 KXH40703.1 - 2.4e-23 82.4 1.0 5e-23 81.4 1.0 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KXH40703.1 - 3.1e-09 36.8 0.0 7.3e-09 35.6 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like PAG PF15347.6 KXH40706.1 - 0.18 10.8 0.1 0.26 10.3 0.1 1.1 1 0 0 1 1 1 0 Phosphoprotein associated with glycosphingolipid-enriched ADH_N PF08240.12 KXH40707.1 - 2.8e-29 101.2 3.0 4.7e-29 100.4 3.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXH40707.1 - 1.3e-12 47.8 0.0 2.2e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KXH40707.1 - 0.0018 17.8 1.2 0.044 13.3 1.2 2.7 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KXH40707.1 - 0.11 13.5 0.0 0.22 12.6 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase DUF4106 PF13388.6 KXH40707.1 - 0.78 8.9 2.8 1 8.5 2.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Phosphatase PF15698.5 KXH40707.1 - 1.2 8.2 4.5 0.18 10.9 0.6 1.5 2 0 0 2 2 2 0 Phosphatase Aldo_ket_red PF00248.21 KXH40708.1 - 3.6e-46 157.7 0.0 4.7e-46 157.3 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Zn_clus PF00172.18 KXH40709.1 - 0.052 13.7 0.4 0.1 12.7 0.4 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KXH40709.1 - 0.072 11.9 0.0 0.13 11.1 0.0 1.4 1 0 0 1 1 1 0 Fungal specific transcription factor domain Fungal_trans_2 PF11951.8 KXH40710.1 - 2.2e-16 59.6 0.9 2.2e-16 59.6 0.9 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain MIT PF04212.18 KXH40710.1 - 0.14 12.2 0.1 0.45 10.6 0.0 1.9 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain ETX_MTX2 PF03318.13 KXH40710.1 - 0.17 11.7 1.7 2.3 7.9 4.0 1.6 2 0 0 2 2 2 0 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 SelP_N PF04592.14 KXH40710.1 - 0.9 8.9 8.3 1.5 8.2 8.3 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region SOG2 PF10428.9 KXH40710.1 - 2.2 7.4 10.4 3 6.9 10.4 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Ndc1_Nup PF09531.10 KXH40710.1 - 5.7 5.5 8.8 3.1 6.4 6.0 1.7 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup Bac_rhamnosid6H PF17389.2 KXH40711.1 - 3.5e-126 421.1 0.0 4.4e-126 420.7 0.0 1.1 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_N PF08531.10 KXH40711.1 - 1.6e-51 174.6 0.0 3.1e-51 173.6 0.0 1.5 1 0 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain Bac_rhamnosid PF05592.11 KXH40711.1 - 1e-25 89.6 0.0 6e-25 87.2 0.0 2.1 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase concanavalin-like domain Bac_rhamnosid_C PF17390.2 KXH40711.1 - 1.9e-20 72.4 0.0 4.2e-20 71.3 0.0 1.6 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain Peptidase_M28 PF04389.17 KXH40712.1 - 5.1e-24 85.1 0.0 1.1e-23 84.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KXH40712.1 - 7.3e-09 35.6 0.3 4.9e-08 32.9 0.3 2.1 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Cnl2_NKP2 PF09447.10 KXH40712.1 - 0.03 14.4 0.7 0.32 11.2 0.2 2.2 2 0 0 2 2 2 0 Cnl2/NKP2 family protein Isochorismatase PF00857.20 KXH40713.1 - 4.5e-38 131.2 0.0 5e-38 131.0 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family Lipocalin_2 PF08212.12 KXH40714.1 - 4.5e-19 68.8 0.0 5.5e-19 68.5 0.0 1.1 1 0 0 1 1 1 1 Lipocalin-like domain Lipocalin PF00061.23 KXH40714.1 - 0.0021 18.3 0.0 0.0068 16.6 0.0 1.7 1 1 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family DUF5546 PF17700.1 KXH40714.1 - 0.034 14.5 0.4 0.1 13.0 0.1 1.9 1 1 1 2 2 2 0 Family of unknown function (DUF5546) DUF3140 PF11338.8 KXH40715.1 - 7.5e-35 119.2 2.1 7.5e-35 119.2 2.1 3.4 2 1 1 3 3 3 1 Protein of unknown function (DUF3140) Hva1_TUDOR PF11160.8 KXH40715.1 - 9.7e-15 54.5 2.2 9.7e-15 54.5 2.2 3.1 2 0 0 2 2 2 1 Hypervirulence associated proteins TUDOR domain KIND PF16474.5 KXH40715.1 - 0.086 12.7 0.2 0.086 12.7 0.2 3.6 2 1 0 2 2 2 0 Kinase non-catalytic C-lobe domain CDC27 PF09507.10 KXH40715.1 - 0.32 10.4 42.2 0.44 9.9 42.2 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 CCDC71L PF15374.6 KXH40715.1 - 3.3 6.9 19.8 4.8 6.3 19.8 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 71L Cupin_1 PF00190.22 KXH40716.1 - 6.1e-38 129.8 0.0 1.1e-19 70.5 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 KXH40716.1 - 3e-26 90.9 0.6 6.4e-13 48.2 0.1 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 KXH40716.1 - 1e-08 34.7 0.0 0.00034 20.3 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.19 KXH40716.1 - 3.1e-07 30.4 0.1 0.00067 19.6 0.0 2.4 2 0 0 2 2 2 2 AraC-like ligand binding domain MannoseP_isomer PF01050.18 KXH40716.1 - 0.00048 20.0 0.0 0.024 14.5 0.0 2.2 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase ARD PF03079.14 KXH40716.1 - 0.0082 16.3 0.3 2.8 8.1 0.0 2.3 2 0 0 2 2 2 2 ARD/ARD' family 3-HAO PF06052.12 KXH40716.1 - 0.016 14.8 0.0 0.18 11.4 0.0 2.2 2 0 0 2 2 2 0 3-hydroxyanthranilic acid dioxygenase Cupin_7 PF12973.7 KXH40716.1 - 0.14 12.1 0.4 1.3 8.9 0.1 2.6 2 1 0 2 2 2 0 ChrR Cupin-like domain DUF1275 PF06912.11 KXH40717.1 - 3.4e-48 164.1 15.4 4e-48 163.9 15.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) TOM20_plant PF06552.12 KXH40717.1 - 0.19 11.5 0.0 0.32 10.7 0.0 1.3 1 0 0 1 1 1 0 Plant specific mitochondrial import receptor subunit TOM20 Patatin PF01734.22 KXH40718.1 - 2.7e-22 79.9 0.0 4.6e-22 79.2 0.0 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase zf-RING_UBOX PF13445.6 KXH40718.1 - 0.0031 17.5 7.2 0.012 15.7 7.2 2.1 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KXH40718.1 - 0.0061 16.4 6.2 0.029 14.2 5.6 2.2 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KXH40718.1 - 0.021 15.0 5.3 0.044 14.0 0.7 2.5 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KXH40718.1 - 0.027 14.3 5.3 0.076 12.9 5.3 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KXH40718.1 - 0.057 13.8 6.1 0.17 12.2 6.1 1.9 1 0 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.6 KXH40718.1 - 0.078 13.0 6.5 0.22 11.5 6.5 1.8 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KXH40718.1 - 0.27 11.1 5.8 0.6 10.0 5.8 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXH40718.1 - 2.8 7.8 7.6 14 5.6 6.8 2.5 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) adh_short PF00106.25 KXH40719.1 - 6.5e-27 94.3 0.0 1.1e-26 93.5 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXH40719.1 - 2.9e-20 72.8 0.0 1e-19 71.0 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KXH40719.1 - 0.00072 19.1 0.0 0.0012 18.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KXH40719.1 - 0.077 12.9 1.5 0.33 10.9 0.3 2.4 2 1 0 2 2 2 0 KR domain Eno-Rase_NADH_b PF12242.8 KXH40719.1 - 0.081 12.7 0.2 0.19 11.5 0.0 1.7 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase EHN PF06441.12 KXH40721.1 - 9.8e-31 106.3 0.3 1.8e-30 105.5 0.3 1.4 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 KXH40721.1 - 3.3e-08 33.5 0.1 1.1e-07 31.8 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXH40721.1 - 0.0082 16.8 1.3 0.037 14.6 1.3 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family HTH_Tnp_Tc5 PF03221.16 KXH40723.1 - 2.6e-11 43.4 0.0 4.7e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.16 KXH40723.1 - 1.8e-05 24.4 0.0 3.5e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_23 PF13384.6 KXH40723.1 - 0.048 13.5 0.0 0.13 12.1 0.0 1.8 1 0 0 1 1 1 0 Homeodomain-like domain FAD-oxidase_C PF02913.19 KXH40724.1 - 1e-59 202.2 0.1 1.2e-59 202.0 0.1 1.1 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KXH40724.1 - 2.7e-18 66.0 0.0 5.7e-18 65.0 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain FAD_binding_4 PF01565.23 KXH40725.1 - 2.8e-13 49.8 0.0 1.4e-12 47.5 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain SepSecS PF05889.13 KXH40725.1 - 0.0081 14.9 0.0 0.014 14.1 0.0 1.3 1 0 0 1 1 1 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS ANF_receptor PF01094.28 KXH40725.1 - 0.02 14.0 0.1 0.04 13.0 0.1 1.4 1 1 1 2 2 2 0 Receptor family ligand binding region Acetyltransf_1 PF00583.25 KXH40726.1 - 2.3e-08 34.3 0.0 5.1e-07 29.9 0.0 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXH40726.1 - 8e-08 32.6 0.0 1.3e-07 32.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KXH40726.1 - 1.3e-05 25.1 0.0 0.00034 20.6 0.0 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXH40726.1 - 0.0098 15.8 0.1 0.037 14.0 0.1 1.8 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_13 PF13880.6 KXH40726.1 - 0.023 14.7 0.0 0.053 13.5 0.0 1.6 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase SAWADEE PF16719.5 KXH40726.1 - 0.056 13.4 0.0 0.074 13.1 0.0 1.1 1 0 0 1 1 1 0 SAWADEE domain VIT PF08487.10 KXH40727.1 - 8.1e-36 122.6 0.2 1.7e-35 121.5 0.2 1.6 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_3 PF13768.6 KXH40727.1 - 6.4e-26 91.1 0.0 1.2e-25 90.3 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT_2 PF13757.6 KXH40727.1 - 2.4e-13 49.7 0.2 5e-13 48.8 0.2 1.5 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain Nucleoporin_FG PF13634.6 KXH40727.1 - 1.5e-09 38.6 69.5 1e-06 29.5 22.5 5.3 2 1 2 4 4 4 1 Nucleoporin FG repeat region VWA PF00092.28 KXH40727.1 - 1.9e-09 38.0 0.0 5.6e-09 36.5 0.0 1.7 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_2 PF13519.6 KXH40727.1 - 8.1e-09 36.1 0.0 6.9e-08 33.1 0.0 2.4 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 KXH40727.1 - 0.043 13.2 0.0 0.098 12.0 0.0 1.5 1 1 0 1 1 1 0 VWA domain containing CoxE-like protein DUF1655 PF07868.11 KXH40727.1 - 0.22 11.6 0.0 0.45 10.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1655) Fungal_trans PF04082.18 KXH40728.1 - 1e-09 37.9 0.0 5.7e-09 35.4 0.0 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain AflR PF08493.10 KXH40728.1 - 7.5 5.9 8.3 15 4.9 8.3 1.4 1 0 0 1 1 1 0 Aflatoxin regulatory protein COesterase PF00135.28 KXH40729.1 - 7.5e-79 265.9 0.0 9.6e-79 265.6 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXH40729.1 - 7.9e-12 45.5 0.5 1.9e-10 41.0 0.5 2.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 KXH40729.1 - 0.0018 17.9 1.0 0.0058 16.3 1.0 1.7 1 1 0 1 1 1 1 Putative esterase Abhydrolase_6 PF12697.7 KXH40729.1 - 0.01 16.4 3.2 0.01 16.4 3.2 2.6 3 1 0 3 3 3 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KXH40729.1 - 0.026 14.0 0.2 0.067 12.7 0.1 1.7 2 0 0 2 2 2 0 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KXH40729.1 - 0.045 13.0 0.0 0.12 11.6 0.1 1.6 1 1 0 1 1 1 0 Serine aminopeptidase, S33 MFS_1 PF07690.16 KXH40730.1 - 6.7e-49 166.7 50.4 6.7e-49 166.7 50.4 1.8 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KXH40730.1 - 2.4e-19 69.2 22.5 5e-18 64.8 18.6 2.3 1 1 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KXH40730.1 - 2.2e-16 59.8 7.1 2.2e-16 59.8 7.1 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter Kinocilin PF15033.6 KXH40730.1 - 0.32 10.6 11.6 0.46 10.1 0.6 3.5 4 0 0 4 4 4 0 Kinocilin protein OATP PF03137.20 KXH40730.1 - 8.7 4.5 36.3 0.054 11.8 5.5 4.2 2 2 2 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.24 KXH40731.1 - 2.1e-57 195.0 16.5 2.5e-57 194.7 16.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH40731.1 - 1.5e-18 66.9 34.1 5.1e-17 61.8 16.4 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KXH40731.1 - 0.0076 14.8 24.8 0.058 11.9 11.3 3.1 2 2 1 3 3 3 3 MFS/sugar transport protein HhH-GPD PF00730.25 KXH40732.1 - 2.5e-08 34.3 0.0 1.2e-07 32.1 0.0 2.4 1 1 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 KXH40732.1 - 0.028 14.3 0.0 0.085 12.8 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix motif zf-PHD-like PF15446.6 KXH40732.1 - 1.5 8.4 6.1 8.6 5.9 1.5 2.3 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain Ndc1_Nup PF09531.10 KXH40732.1 - 1.6 7.3 5.8 1.7 7.2 5.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Epimerase PF01370.21 KXH40734.1 - 1.7e-08 34.2 0.1 3.2e-05 23.5 0.1 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXH40734.1 - 4.1e-08 32.6 0.0 4.4e-06 25.9 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KXH40734.1 - 1.1e-06 28.7 0.0 1.8e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KXH40734.1 - 3e-05 23.7 0.1 0.00017 21.3 0.1 1.9 2 0 0 2 2 2 1 NmrA-like family Semialdhyde_dh PF01118.24 KXH40734.1 - 0.00028 21.3 0.0 0.00061 20.2 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.12 KXH40734.1 - 0.0016 17.6 0.1 0.0088 15.2 0.1 2.1 2 1 0 2 2 2 1 Male sterility protein GDP_Man_Dehyd PF16363.5 KXH40734.1 - 0.0033 16.9 0.2 0.0099 15.3 0.1 1.8 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 KXH40735.1 - 1.3e-59 201.6 0.0 1.5e-59 201.4 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXH40735.1 - 2.5e-14 53.6 0.1 3.5e-14 53.1 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KXH40735.1 - 0.00034 19.7 0.0 0.00049 19.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KXH40735.1 - 0.0075 15.8 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KXH40736.1 - 2.2e-12 47.0 0.0 3.1e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXH40736.1 - 3.1e-11 43.5 0.0 6.7e-11 42.4 0.0 1.5 2 0 0 2 2 2 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KXH40736.1 - 1.5e-06 28.5 0.0 3.7e-05 24.0 0.0 2.3 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 KXH40736.1 - 0.0012 18.4 0.0 0.002 17.7 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.20 KXH40736.1 - 0.018 15.2 0.1 0.041 14.0 0.1 1.7 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NAD_binding_4 PF07993.12 KXH40736.1 - 0.033 13.3 0.1 0.085 12.0 0.0 1.6 2 0 0 2 2 2 0 Male sterility protein DUF1828 PF08861.10 KXH40736.1 - 0.035 14.4 0.0 0.24 11.7 0.0 2.3 3 0 0 3 3 3 0 Domain of unknown function DUF1828 Semialdhyde_dh PF01118.24 KXH40736.1 - 0.041 14.3 0.1 0.23 11.9 0.0 2.0 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 KXH40736.1 - 0.061 12.4 0.0 0.093 11.9 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Shikimate_DH PF01488.20 KXH40736.1 - 0.089 12.9 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 3Beta_HSD PF01073.19 KXH40736.1 - 0.15 11.1 0.0 0.31 10.0 0.0 1.5 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family KAP_NTPase PF07693.14 KXH40738.1 - 0.00012 21.4 0.1 0.00012 21.4 0.1 1.1 1 0 0 1 1 1 1 KAP family P-loop domain NmrA PF05368.13 KXH40742.1 - 3.8e-20 72.5 0.0 6.2e-20 71.8 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXH40742.1 - 8e-16 58.5 0.0 1.4e-15 57.6 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KXH40742.1 - 6.6e-08 32.3 1.0 2.8e-05 23.7 0.5 2.8 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXH40742.1 - 0.00098 18.6 0.1 0.015 14.7 0.0 2.1 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase TrkA_N PF02254.18 KXH40742.1 - 0.0018 18.5 0.0 0.0034 17.6 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain RmlD_sub_bind PF04321.17 KXH40742.1 - 0.011 14.8 0.2 0.021 14.0 0.1 1.5 2 0 0 2 2 2 0 RmlD substrate binding domain F420_oxidored PF03807.17 KXH40742.1 - 0.014 16.0 0.0 0.032 14.8 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent adh_short PF00106.25 KXH40742.1 - 0.15 11.5 0.1 0.21 11.0 0.1 1.2 1 0 0 1 1 1 0 short chain dehydrogenase DapB_N PF01113.20 KXH40742.1 - 0.17 12.0 0.1 0.28 11.3 0.1 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NAD_binding_2 PF03446.15 KXH40742.1 - 0.22 11.7 0.0 0.38 10.9 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase ADH_N PF08240.12 KXH40743.1 - 6.7e-08 32.4 0.0 1.2e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXH40743.1 - 2.5e-07 30.7 0.2 5.1e-07 29.7 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXH40743.1 - 0.00018 22.5 0.0 0.00035 21.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Epimerase PF01370.21 KXH40743.1 - 0.045 13.2 0.0 0.065 12.7 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Cu_bind_like PF02298.17 KXH40744.1 - 0.021 14.8 0.0 0.041 13.9 0.0 1.4 1 0 0 1 1 1 0 Plastocyanin-like domain Epimerase PF01370.21 KXH40745.1 - 4.2e-11 42.8 0.0 8.5e-11 41.8 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KXH40745.1 - 3.5e-06 26.8 0.3 6.9e-05 22.5 0.1 2.1 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.6 KXH40745.1 - 0.00071 19.5 0.0 0.0012 18.8 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 KXH40745.1 - 0.0019 17.7 0.3 0.0058 16.1 0.1 1.9 2 0 0 2 2 2 1 short chain dehydrogenase GDP_Man_Dehyd PF16363.5 KXH40745.1 - 0.0031 17.0 0.0 0.03 13.7 0.0 2.1 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Gti1_Pac2 PF09729.9 KXH40820.1 - 1e-42 146.3 6.2 1.6e-36 126.1 0.3 2.7 2 1 1 3 3 3 2 Gti1/Pac2 family SLD3 PF08639.10 KXH40824.1 - 0.055 12.2 0.1 0.066 12.0 0.1 1.1 1 0 0 1 1 1 0 DNA replication regulator SLD3 Bac_DNA_binding PF00216.21 KXH40825.1 - 0.08 13.2 0.1 11 6.2 0.1 2.6 3 0 0 3 3 3 0 Bacterial DNA-binding protein TMEM154 PF15102.6 KXH40838.1 - 0.029 14.3 0.0 0.044 13.7 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family EphA2_TM PF14575.6 KXH40838.1 - 0.049 14.5 0.0 0.066 14.1 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain CD34_antigen PF06365.12 KXH40838.1 - 0.15 11.6 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family Sulfatase PF00884.23 KXH40839.1 - 2.5e-47 161.8 0.0 3.7e-47 161.2 0.0 1.2 1 0 0 1 1 1 1 Sulfatase DUF4976 PF16347.5 KXH40839.1 - 0.0006 20.0 0.0 0.0013 19.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4976) DUF229 PF02995.17 KXH40839.1 - 0.042 12.5 0.0 0.054 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Phosphodiest PF01663.22 KXH40839.1 - 0.044 13.4 0.0 0.33 10.5 0.0 2.1 2 0 0 2 2 2 0 Type I phosphodiesterase / nucleotide pyrophosphatase Ank_2 PF12796.7 KXH40861.1 - 6.4e-57 190.1 0.0 2.9e-10 40.6 0.0 6.5 6 0 0 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXH40861.1 - 6.7e-46 154.1 0.2 8.4e-07 29.4 0.0 11.9 6 4 7 13 13 13 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXH40861.1 - 2.1e-41 135.2 5.2 0.00031 20.9 0.0 15.4 17 0 0 17 17 17 9 Ankyrin repeat Ank_5 PF13857.6 KXH40861.1 - 3.6e-40 135.5 3.0 1e-06 28.9 0.0 9.9 6 2 2 9 9 9 8 Ankyrin repeats (many copies) Ank PF00023.30 KXH40861.1 - 3.4e-37 125.3 9.4 0.00095 19.5 0.0 13.9 14 1 0 14 14 14 9 Ankyrin repeat GST_N_3 PF13417.6 KXH40862.1 - 1.5e-13 51.0 0.0 1.9e-13 50.6 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KXH40862.1 - 5.1e-10 39.5 0.0 7.6e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KXH40862.1 - 1.5e-09 38.0 0.0 1.8e-09 37.7 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 KXH40862.1 - 0.086 13.6 0.0 0.11 13.3 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain Fungal_trans PF04082.18 KXH40863.1 - 9.1e-25 87.2 1.9 2.7e-24 85.7 0.1 2.4 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH40863.1 - 4.2e-05 23.6 11.0 7.3e-05 22.8 11.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Med7 PF05983.11 KXH40863.1 - 0.01 15.9 0.3 0.02 15.0 0.3 1.4 1 0 0 1 1 1 0 MED7 protein Amidohydro_3 PF07969.11 KXH40865.1 - 1.3e-55 189.8 0.7 1.9e-55 189.2 0.7 1.3 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 KXH40865.1 - 1.3e-13 51.1 0.0 2.4e-10 40.3 0.0 3.2 3 0 0 3 3 3 2 Amidohydrolase family KNTase_C PF07827.11 KXH40866.1 - 0.13 12.1 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 KNTase C-terminal domain FAD_binding_3 PF01494.19 KXH40867.1 - 2.9e-20 72.8 0.0 4.9e-19 68.8 0.0 2.2 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KXH40867.1 - 0.0014 18.8 0.1 0.0031 17.7 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXH40867.1 - 0.0015 17.8 0.2 0.017 14.4 0.0 2.1 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXH40867.1 - 0.0029 17.2 1.3 0.046 13.3 0.8 2.3 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KXH40867.1 - 0.039 14.5 0.1 12 6.5 0.1 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 KXH40867.1 - 0.046 12.8 0.0 6.1 5.8 0.0 2.2 2 0 0 2 2 2 0 Squalene epoxidase NAD_Gly3P_dh_N PF01210.23 KXH40867.1 - 0.051 13.5 0.0 0.088 12.8 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GIDA PF01134.22 KXH40867.1 - 0.079 12.0 0.1 0.11 11.5 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Thi4 PF01946.17 KXH40867.1 - 0.12 11.6 0.1 0.2 10.9 0.1 1.4 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.12 KXH40867.1 - 0.59 9.1 2.7 5.3 6.0 1.0 2.7 2 1 0 2 2 2 0 Lycopene cyclase protein MFS_1 PF07690.16 KXH40941.1 - 3e-28 98.8 69.2 3.5e-19 69.0 34.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyoxalase_6 PF18029.1 KXH40942.1 - 0.0039 18.0 0.0 0.0048 17.7 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.25 KXH40942.1 - 0.041 14.1 0.1 0.27 11.4 0.1 2.0 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Efg1 PF10153.9 KXH40950.1 - 3.7e-32 111.1 13.4 3.7e-32 111.1 13.4 2.8 4 0 0 4 4 4 1 rRNA-processing protein Efg1 FliG_N PF14842.6 KXH40950.1 - 0.017 15.6 0.9 0.033 14.7 0.9 1.4 1 0 0 1 1 1 0 FliG N-terminal domain DUF2813 PF11398.8 KXH40950.1 - 0.96 8.6 13.4 0.31 10.3 8.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2813) zinc_ribbon_16 PF17034.5 KXH40951.1 - 1.2e-16 61.1 8.1 3.4e-16 59.6 8.1 1.8 1 0 0 1 1 1 1 Zinc-ribbon like family Zn_ribbon_17 PF17120.5 KXH40951.1 - 2.7e-06 26.9 5.0 2.7e-06 26.9 5.0 2.4 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type Fungal_trans_2 PF11951.8 KXH40969.1 - 2.6e-06 26.5 0.1 4.1e-06 25.9 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH40969.1 - 5.3e-05 23.3 11.7 0.00011 22.2 11.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TonB_N PF16031.5 KXH40969.1 - 3.6 8.1 8.2 6.7 7.2 8.2 1.4 1 0 0 1 1 1 0 TonB polyproline region Endomucin PF07010.12 KXH40970.1 - 5.2 7.0 16.9 6.2 6.7 16.9 1.1 1 0 0 1 1 1 0 Endomucin Alg6_Alg8 PF03155.15 KXH40971.1 - 2.1e-175 584.4 26.7 2.9e-175 583.9 26.7 1.1 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family WAC_Acf1_DNA_bd PF10537.9 KXH40971.1 - 2e-38 131.0 6.2 2.2e-38 130.9 0.0 3.4 3 0 0 3 3 3 1 ATP-utilising chromatin assembly and remodelling N-terminal WSD PF15613.6 KXH40971.1 - 1.3e-18 67.3 0.1 1.3e-18 67.3 0.1 3.8 4 0 0 4 4 4 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DDT PF02791.17 KXH40971.1 - 8.4e-17 61.2 0.3 2.4e-16 59.8 0.3 1.9 1 0 0 1 1 1 1 DDT domain WHIM1 PF15612.6 KXH40971.1 - 7.7e-07 28.5 0.1 1.2e-05 24.7 0.0 2.5 2 0 0 2 2 2 1 WSTF, HB1, Itc1p, MBD9 motif 1 MerC PF03203.14 KXH40971.1 - 0.0048 17.3 4.1 0.0048 17.3 4.1 2.3 2 0 0 2 2 2 1 MerC mercury resistance protein Lectin_leg-like PF03388.13 KXH40972.1 - 5e-25 88.2 0.0 8.3e-25 87.5 0.0 1.3 1 0 0 1 1 1 1 Legume-like lectin family DUF5523 PF17661.1 KXH40972.1 - 0.0048 16.6 1.0 0.0072 16.1 1.0 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5523) TFIIA PF03153.13 KXH40972.1 - 0.0061 16.6 7.1 0.0078 16.3 7.1 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 KXH40972.1 - 0.012 15.2 11.3 0.019 14.6 11.3 1.2 1 0 0 1 1 1 0 Spt20 family Baculo_PEP_C PF04513.12 KXH40972.1 - 0.014 15.4 2.3 0.039 14.0 2.2 1.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Tmemb_cc2 PF10267.9 KXH40972.1 - 0.018 14.2 8.0 0.026 13.7 8.0 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein PDGLE PF13190.6 KXH40972.1 - 0.02 14.7 0.9 0.22 11.4 0.0 2.6 2 0 0 2 2 2 0 PDGLE domain SesA PF17107.5 KXH40972.1 - 0.049 13.8 0.3 0.099 12.8 0.3 1.4 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases MCU PF04678.13 KXH40972.1 - 0.076 13.1 1.8 1 9.4 0.1 2.2 2 0 0 2 2 2 0 Mitochondrial calcium uniporter CCDC53 PF10152.9 KXH40972.1 - 0.15 12.5 6.7 5 7.5 0.1 2.2 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex DUF4175 PF13779.6 KXH40972.1 - 0.64 7.9 13.3 0.82 7.5 13.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) FAM76 PF16046.5 KXH40972.1 - 1.8 7.8 9.7 3.4 6.9 9.7 1.3 1 0 0 1 1 1 0 FAM76 protein Med3 PF11593.8 KXH40972.1 - 2.6 7.2 17.7 3.9 6.6 13.6 2.2 1 1 1 2 2 2 0 Mediator complex subunit 3 fungal Presenilin PF01080.17 KXH40972.1 - 4.7 5.9 4.5 6.8 5.3 4.5 1.2 1 0 0 1 1 1 0 Presenilin DUF4834 PF16118.5 KXH40972.1 - 5.8 7.9 7.8 4.1 8.4 5.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Peptidase_M24 PF00557.24 KXH40973.1 - 2.6e-58 197.1 0.1 5.9e-58 196.0 0.1 1.6 1 1 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 KXH40973.1 - 1.3e-19 70.1 0.0 2.8e-19 69.0 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Fungal_trans PF04082.18 KXH40974.1 - 3.1e-31 108.4 0.0 1.1e-30 106.6 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH40974.1 - 1e-10 41.6 13.6 1.9e-10 40.7 13.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fer2 PF00111.27 KXH40974.1 - 0.092 12.7 2.9 1.4 8.9 0.0 2.4 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain Gal4_dimer PF03902.13 KXH40974.1 - 0.16 12.1 0.1 0.45 10.7 0.1 1.7 1 0 0 1 1 1 0 Gal4-like dimerisation domain Sugarporin_N PF11471.8 KXH40974.1 - 5.2 7.1 5.1 11 6.1 0.8 2.7 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension PAD PF03068.15 KXH40975.1 - 2.3e-35 122.4 0.0 2.7e-35 122.1 0.0 1.1 1 0 0 1 1 1 1 Protein-arginine deiminase (PAD) Omega-toxin PF06357.11 KXH40976.1 - 0.039 13.7 4.0 0.093 12.5 4.0 1.7 1 0 0 1 1 1 0 Omega-atracotoxin Thioredoxin PF00085.20 KXH40977.1 - 2.3e-28 98.2 0.1 1.8e-12 47.2 0.0 3.4 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 KXH40977.1 - 4.9e-22 78.7 1.3 1.2e-15 57.9 0.2 3.3 2 1 1 3 3 3 3 Thioredoxin-like domain Thioredoxin_2 PF13098.6 KXH40977.1 - 6.3e-06 26.6 0.6 0.3 11.5 0.0 3.4 4 1 0 4 4 4 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 KXH40977.1 - 0.00057 20.0 0.0 1.8 8.8 0.0 2.7 2 0 0 2 2 2 2 Thioredoxin-like Glutaredoxin PF00462.24 KXH40977.1 - 0.00096 19.3 0.6 0.45 10.8 0.0 2.7 2 1 0 2 2 2 2 Glutaredoxin Thioredoxin_8 PF13905.6 KXH40977.1 - 0.0054 17.0 0.4 15 6.0 0.0 3.8 4 0 0 4 4 4 1 Thioredoxin-like DUF836 PF05768.14 KXH40977.1 - 0.11 12.9 0.1 3.3 8.2 0.1 2.6 2 0 0 2 2 2 0 Glutaredoxin-like domain (DUF836) Flavoprotein PF02441.19 KXH40978.1 - 1.4e-26 93.2 0.0 1.6e-26 93.0 0.0 1.1 1 0 0 1 1 1 1 Flavoprotein Lin0512_fam PF09585.10 KXH40978.1 - 0.12 12.4 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical protein (Lin0512_fam) UbiD PF01977.16 KXH40979.1 - 1.7e-111 373.0 0.0 2e-111 372.7 0.0 1.0 1 0 0 1 1 1 1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase FAD_binding_3 PF01494.19 KXH40980.1 - 4.1e-23 82.2 0.0 1.3e-22 80.6 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.24 KXH40980.1 - 0.00091 18.6 0.1 0.12 11.6 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.12 KXH40980.1 - 0.0031 16.6 0.4 0.73 8.8 0.0 2.4 3 0 0 3 3 3 2 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KXH40980.1 - 0.0047 16.2 0.6 0.039 13.2 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXH40980.1 - 0.0048 17.4 5.0 0.018 15.6 0.1 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KXH40980.1 - 0.0058 15.5 0.0 0.46 9.3 0.0 2.7 2 1 1 3 3 3 1 Tryptophan halogenase DAO PF01266.24 KXH40980.1 - 0.01 15.4 0.2 0.05 13.2 0.1 2.0 1 1 1 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KXH40980.1 - 0.12 11.6 2.9 1.4 8.1 0.1 2.5 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXH40980.1 - 0.16 12.2 0.0 0.42 10.9 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KXH40981.1 - 2.1e-44 152.2 0.0 2.5e-44 152.0 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KXH40981.1 - 1.9e-05 24.4 0.1 0.0005 19.8 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KXH40981.1 - 3e-05 23.3 0.0 5.6e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KXH40981.1 - 0.00011 21.1 0.0 0.00017 20.4 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.14 KXH40981.1 - 0.00018 20.9 0.0 0.00046 19.5 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXH40981.1 - 0.00032 20.9 0.0 0.00074 19.7 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KXH40981.1 - 0.0025 18.3 0.2 0.01 16.4 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KXH40981.1 - 0.0031 16.6 0.1 0.0052 15.9 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KXH40981.1 - 0.0032 16.8 0.0 0.0057 15.9 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXH40981.1 - 0.0036 16.6 0.0 0.0094 15.2 0.1 1.6 2 0 0 2 2 2 1 Thi4 family UDPG_MGDP_dh_N PF03721.14 KXH40981.1 - 0.035 13.7 0.1 0.071 12.7 0.1 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.16 KXH40981.1 - 0.062 12.9 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_oxidored PF12831.7 KXH40981.1 - 0.063 12.6 0.2 0.25 10.6 0.2 1.9 1 1 0 1 1 1 0 FAD dependent oxidoreductase 3HCDH_N PF02737.18 KXH40981.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain adh_short PF00106.25 KXH40982.1 - 1.5e-35 122.5 0.0 1.9e-35 122.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXH40982.1 - 2.7e-32 112.2 0.0 3.4e-32 111.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH40982.1 - 7e-09 35.8 0.0 1.1e-08 35.2 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXH40982.1 - 0.00034 20.1 0.0 0.00048 19.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KXH40982.1 - 0.015 14.5 0.0 0.021 14.0 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 2-Hacid_dh_C PF02826.19 KXH40982.1 - 0.051 12.9 0.0 0.083 12.3 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ACT_7 PF13840.6 KXH40982.1 - 0.07 12.9 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 ACT domain p450 PF00067.22 KXH40983.1 - 1.2e-53 182.5 0.0 1.7e-38 132.6 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 p450 PF00067.22 KXH40984.1 - 2.1e-65 221.3 0.0 2.4e-65 221.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_32N PF00251.20 KXH40985.1 - 4.8e-76 256.2 3.3 5.9e-76 255.9 3.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 KXH40985.1 - 7.7e-05 22.7 0.1 0.00014 21.9 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal p450 PF00067.22 KXH40986.1 - 1.7e-35 122.7 0.0 2e-35 122.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF4501 PF14946.6 KXH40986.1 - 0.24 11.5 0.6 0.37 10.8 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4501) Acetyltransf_10 PF13673.7 KXH40987.1 - 7.3e-12 45.3 0.0 9.2e-12 45.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXH40987.1 - 1.9e-11 44.2 0.0 2.2e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXH40987.1 - 3.7e-08 33.7 0.0 5.4e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KXH40987.1 - 0.00078 19.5 0.5 0.066 13.3 0.5 2.3 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXH40987.1 - 0.0037 17.2 0.0 0.0077 16.2 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein DUF5446 PF17522.2 KXH40989.1 - 0.019 15.1 0.8 0.019 15.1 0.8 4.1 4 0 0 4 4 4 0 Family of unknown function (DUF5446) DUF1664 PF07889.12 KXH40989.1 - 1.9 8.6 12.4 0.76 9.8 1.0 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) HMMR_N PF15905.5 KXH40989.1 - 2.2 7.6 29.1 0.037 13.5 6.6 2.7 1 1 2 3 3 3 0 Hyaluronan mediated motility receptor N-terminal MCPsignal PF00015.21 KXH40989.1 - 4.4 7.1 11.1 0.68 9.7 1.9 2.5 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF4363 PF14276.6 KXH40989.1 - 8.2 6.6 8.3 0.6 10.2 0.2 3.2 4 0 0 4 4 4 0 Domain of unknown function (DUF4363) PIN_8 PF18476.1 KXH40989.1 - 9.4 6.0 11.4 5.3 6.8 0.7 2.9 2 1 0 2 2 2 0 PIN like domain adh_short_C2 PF13561.6 KXH40990.1 - 5.4e-61 206.1 0.3 6.5e-61 205.9 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXH40990.1 - 6.1e-46 156.3 0.2 7.3e-46 156.1 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXH40990.1 - 6.8e-11 42.4 0.4 1.7e-10 41.1 0.4 1.6 1 1 1 2 2 2 1 KR domain Epimerase PF01370.21 KXH40990.1 - 3.4e-05 23.4 0.1 6.1e-05 22.6 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 KXH40990.1 - 3.8e-05 23.2 0.0 5.4e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Polysacc_synt_2 PF02719.15 KXH40990.1 - 0.0032 16.6 0.1 0.0043 16.2 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein ADH_zinc_N PF00107.26 KXH40990.1 - 0.089 12.8 1.4 0.45 10.5 1.4 2.1 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Vta1 PF04652.16 KXH40991.1 - 2.8e-55 186.3 2.9 2.8e-55 186.3 2.9 1.7 2 0 0 2 2 2 1 Vta1 like Vta1_C PF18097.1 KXH40991.1 - 1.6e-16 59.7 1.5 1.9e-16 59.5 0.1 1.9 2 0 0 2 2 2 1 Vta1 C-terminal domain RBM39linker PF15519.6 KXH40991.1 - 0.048 14.8 0.2 0.048 14.8 0.2 2.7 2 1 0 2 2 2 0 linker between RRM2 and RRM3 domains in RBM39 protein DUF3731 PF12531.8 KXH40991.1 - 0.053 13.3 0.2 0.085 12.7 0.2 1.3 1 0 0 1 1 1 0 DNA-K related protein HEAT_EZ PF13513.6 KXH40991.1 - 0.094 13.2 0.4 9 6.9 0.0 2.8 2 1 0 2 2 2 0 HEAT-like repeat Thioredoxin PF00085.20 KXH40992.1 - 5.7e-34 116.2 0.0 9.5e-27 93.0 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_6 PF13848.6 KXH40992.1 - 2.7e-12 47.0 0.0 0.00019 21.4 0.0 3.2 2 1 1 3 3 3 3 Thioredoxin-like domain OST3_OST6 PF04756.13 KXH40992.1 - 3e-07 30.1 0.0 4e-06 26.4 0.0 2.2 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 KXH40992.1 - 1.1e-06 29.0 0.3 0.025 15.0 0.1 2.7 1 1 1 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KXH40992.1 - 0.0015 18.8 0.0 1.9 8.9 0.0 4.1 3 2 1 4 4 4 1 Thioredoxin-like ERp29_N PF07912.13 KXH40992.1 - 0.015 15.5 0.0 1.3 9.2 0.0 2.4 2 0 0 2 2 2 0 ERp29, N-terminal domain TraF PF13728.6 KXH40992.1 - 0.016 15.0 0.0 0.016 15.0 0.0 4.0 4 0 0 4 4 2 0 F plasmid transfer operon protein Thioredoxin_3 PF13192.6 KXH40992.1 - 0.017 15.2 0.1 1.3 9.1 0.1 2.6 2 0 0 2 2 2 0 Thioredoxin domain Thioredoxin_7 PF13899.6 KXH40992.1 - 0.023 14.9 0.0 0.047 13.9 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like QSOX_Trx1 PF18108.1 KXH40992.1 - 0.038 14.2 0.0 0.097 12.9 0.0 1.6 1 0 0 1 1 1 0 QSOX Trx-like domain AhpC-TSA PF00578.21 KXH40992.1 - 0.043 13.7 0.1 0.69 9.8 0.0 2.4 2 0 0 2 2 2 0 AhpC/TSA family Calsequestrin PF01216.17 KXH40992.1 - 0.058 12.4 0.1 0.61 9.1 0.0 2.4 2 1 1 3 3 3 0 Calsequestrin CCDC53 PF10152.9 KXH40992.1 - 0.074 13.5 6.8 0.36 11.2 1.2 2.4 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex HyaE PF07449.11 KXH40992.1 - 0.091 12.7 0.0 5.5 7.0 0.0 3.1 2 1 0 2 2 2 0 Hydrogenase-1 expression protein HyaE CPSF100_C PF13299.6 KXH40992.1 - 0.28 11.3 3.3 0.16 12.1 0.5 2.0 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal NARP1 PF12569.8 KXH40992.1 - 0.29 10.0 2.1 0.43 9.4 2.1 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 SWIRM-assoc_2 PF16496.5 KXH40992.1 - 0.61 8.9 5.3 1.2 7.9 5.3 1.4 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal RNase_PH PF01138.21 KXH40993.1 - 8.3e-36 123.4 0.2 1.2e-35 122.9 0.2 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 NIF PF03031.18 KXH40995.1 - 5.5e-38 130.2 0.0 7.9e-38 129.7 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase TMEM208_SND2 PF05620.11 KXH40996.1 - 0.0031 17.3 0.2 0.0061 16.4 0.2 1.4 1 0 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 Tim17 PF02466.19 KXH40998.1 - 0.00013 22.4 4.4 0.00021 21.7 3.0 1.9 1 1 1 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family Pro_dh PF01619.18 KXH40999.1 - 1e-54 186.1 0.0 1.2e-54 185.9 0.0 1.0 1 0 0 1 1 1 1 Proline dehydrogenase CGI-121 PF08617.10 KXH41000.1 - 1.9e-54 184.2 0.0 2.2e-54 184.0 0.0 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 Fungal_trans PF04082.18 KXH41001.1 - 3.9e-12 45.8 0.0 7e-12 44.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH41001.1 - 4.7e-08 33.0 6.7 8.2e-08 32.2 6.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.24 KXH41002.1 - 3.3e-120 402.0 21.3 3.8e-120 401.8 21.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH41002.1 - 8.7e-24 84.1 57.6 1.2e-21 77.1 27.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily BNR_4 PF15892.5 KXH41003.1 - 4.1e-69 233.0 4.1 6e-69 232.4 4.1 1.2 1 0 0 1 1 1 1 BNR repeat-containing family member BNR PF02012.20 KXH41003.1 - 0.086 12.9 0.6 0.086 12.9 0.6 2.7 2 0 0 2 2 2 0 BNR/Asp-box repeat BNR_2 PF13088.6 KXH41003.1 - 0.087 12.1 0.0 0.37 10.1 0.0 2.0 2 1 0 2 2 2 0 BNR repeat-like domain Asp PF00026.23 KXH41004.1 - 2.9e-76 256.9 13.7 3.5e-76 256.7 13.7 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KXH41004.1 - 3.4e-14 53.5 7.2 1.1e-07 32.3 0.1 2.8 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KXH41004.1 - 0.00028 21.5 3.2 0.044 14.4 1.0 3.0 2 1 0 2 2 2 2 Aspartyl protease Kinesin PF00225.23 KXH41006.1 - 4.5e-117 390.7 0.0 6e-117 390.3 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KXH41006.1 - 9.6e-29 100.2 0.0 2e-28 99.2 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding Herpes_UL14 PF03580.14 KXH41006.1 - 0.0089 16.3 2.6 0.027 14.7 2.6 1.8 1 0 0 1 1 1 1 Herpesvirus UL14-like protein Peptidase_M42 PF05343.14 KXH41006.1 - 0.062 12.3 0.1 0.1 11.6 0.1 1.3 1 0 0 1 1 1 0 M42 glutamyl aminopeptidase Glyco_hydro_115 PF15979.5 KXH41007.1 - 1.6e-134 448.7 0.9 2.7e-134 447.9 0.9 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 115 GH115_C PF17829.1 KXH41007.1 - 2.5e-50 170.6 0.0 5.4e-50 169.6 0.0 1.6 1 0 0 1 1 1 1 Gylcosyl hydrolase family 115 C-terminal domain Glyco_hydro_67N PF03648.14 KXH41007.1 - 0.089 13.1 0.0 0.38 11.0 0.0 2.1 2 0 0 2 2 2 0 Glycosyl hydrolase family 67 N-terminus HET PF06985.11 KXH41008.1 - 8.3e-12 45.7 7.7 9.9e-10 38.9 2.8 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) zf-C2H2_4 PF13894.6 KXH41009.1 - 2.3e-07 31.1 2.0 0.013 16.3 0.1 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KXH41009.1 - 6.9e-06 26.2 2.8 0.036 14.5 0.1 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type Axin_b-cat_bind PF08833.10 KXH41009.1 - 0.02 15.0 0.1 0.055 13.6 0.1 1.7 1 0 0 1 1 1 0 Axin beta-catenin binding domain zf-Di19 PF05605.12 KXH41009.1 - 0.21 11.9 1.2 6.1 7.2 0.8 2.2 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding TSKS PF15358.6 KXH41009.1 - 0.58 8.5 3.2 0.19 10.0 0.5 1.5 2 0 0 2 2 2 0 Testis-specific serine kinase substrate F-box-like PF12937.7 KXH41010.1 - 0.00041 20.2 1.1 0.0013 18.6 1.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXH41010.1 - 0.013 15.3 0.5 0.039 13.8 0.5 1.8 1 0 0 1 1 1 0 F-box domain UQ_con PF00179.26 KXH41012.1 - 2.5e-09 36.9 0.0 5.9e-09 35.7 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme F-box PF00646.33 KXH41012.1 - 0.017 15.0 0.3 0.04 13.8 0.3 1.6 1 0 0 1 1 1 0 F-box domain TRCF PF03461.15 KXH41012.1 - 0.022 15.2 0.0 0.046 14.1 0.0 1.5 1 0 0 1 1 1 0 TRCF domain F-box-like PF12937.7 KXH41012.1 - 0.06 13.3 0.3 0.14 12.1 0.3 1.6 1 0 0 1 1 1 0 F-box-like DUF3844 PF12955.7 KXH41014.1 - 1.6e-35 121.4 4.3 1.9e-35 121.2 3.4 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3844) YabA PF06156.13 KXH41015.1 - 0.056 14.1 3.3 0.14 12.8 0.2 2.7 2 1 1 3 3 3 0 Initiation control protein YabA LSM PF01423.22 KXH41016.1 - 5.4e-21 74.0 0.6 6.1e-21 73.9 0.6 1.0 1 0 0 1 1 1 1 LSM domain Rhodanese PF00581.20 KXH41017.1 - 3.9e-09 37.0 0.0 5e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain Amino_oxidase PF01593.24 KXH41018.1 - 1.3e-61 209.2 0.0 1.7e-61 208.9 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KXH41018.1 - 3.6e-08 33.5 0.3 1.2e-07 31.8 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXH41018.1 - 8.1e-05 22.3 0.0 0.00041 20.0 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KXH41018.1 - 0.00033 19.9 0.0 0.00051 19.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 KXH41018.1 - 0.0055 16.0 0.4 0.0095 15.2 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KXH41018.1 - 0.0098 15.2 0.0 0.038 13.2 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXH41018.1 - 0.013 14.2 0.0 0.024 13.4 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.6 KXH41018.1 - 0.068 12.4 0.3 0.14 11.4 0.3 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXH41018.1 - 0.09 12.0 0.1 0.16 11.2 0.1 1.3 1 0 0 1 1 1 0 Thi4 family DAO PF01266.24 KXH41020.1 - 2.8e-28 99.5 0.0 3.4e-28 99.3 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KXH41020.1 - 0.05 12.9 0.0 0.077 12.2 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase COesterase PF00135.28 KXH41022.1 - 1e-58 199.5 0.0 2.3e-58 198.3 0.0 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXH41022.1 - 8.6e-07 29.0 0.1 1.5e-06 28.2 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold PgdA_N PF18627.1 KXH41022.1 - 0.27 10.9 0.0 0.4 10.3 0.0 1.2 1 0 0 1 1 1 0 Peptidoglycan GlcNAc deacetylase N-terminal domain TYA PF01021.19 KXH41023.1 - 0.012 16.0 0.1 0.023 15.0 0.1 1.4 1 0 0 1 1 1 0 TYA transposon protein SAM_decarbox PF01536.16 KXH41024.1 - 1.5e-132 442.0 0.0 1.8e-132 441.6 0.0 1.1 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase ParA PF10609.9 KXH41025.1 - 1.7e-91 306.1 0.1 2.1e-91 305.7 0.1 1.2 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 KXH41025.1 - 5.4e-11 42.6 0.0 5.7e-10 39.3 0.0 2.2 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.11 KXH41025.1 - 4.2e-07 29.5 0.0 7e-06 25.5 0.0 2.1 2 0 0 2 2 2 1 ATPase MipZ AAA_31 PF13614.6 KXH41025.1 - 4e-06 26.9 0.1 0.00032 20.7 0.1 2.2 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.15 KXH41025.1 - 7.9e-05 22.0 0.4 0.00018 20.8 0.4 1.5 1 0 0 1 1 1 1 Anion-transporting ATPase MeaB PF03308.16 KXH41025.1 - 0.00049 19.2 0.1 0.00075 18.6 0.1 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_25 PF13481.6 KXH41025.1 - 0.00098 18.8 0.1 0.0018 17.9 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_26 PF13500.6 KXH41025.1 - 0.0079 16.0 0.6 0.42 10.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain CBP_BcsQ PF06564.12 KXH41025.1 - 0.029 13.9 0.7 0.078 12.4 0.7 1.7 1 1 0 1 1 1 0 Cellulose biosynthesis protein BcsQ RsgA_GTPase PF03193.16 KXH41025.1 - 0.033 14.1 1.0 0.06 13.3 0.3 1.7 2 0 0 2 2 2 0 RsgA GTPase Zeta_toxin PF06414.12 KXH41025.1 - 0.035 13.4 0.0 0.059 12.6 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin APS_kinase PF01583.20 KXH41025.1 - 0.071 13.0 0.1 0.11 12.3 0.1 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_16 PF13191.6 KXH41025.1 - 0.19 12.1 0.4 0.51 10.7 0.3 1.7 2 0 0 2 2 2 0 AAA ATPase domain p450 PF00067.22 KXH41027.1 - 1.4e-94 317.5 0.0 1.6e-94 317.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Zn_clus PF00172.18 KXH41028.1 - 1e-18 67.1 27.7 3.5e-10 39.8 7.1 2.5 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXH41028.1 - 1.1e-09 37.8 0.0 2.1e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain NOB1_Zn_bind PF08772.11 KXH41029.1 - 2e-32 111.1 3.1 3.4e-32 110.4 3.1 1.4 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like PIN_6 PF17146.4 KXH41029.1 - 1.1e-29 102.8 0.9 2.5e-29 101.6 0.0 2.0 2 0 0 2 2 2 1 PIN domain of ribonuclease PIN_5 PF08745.11 KXH41029.1 - 0.02 14.3 0.2 10 5.5 0.0 3.2 2 1 1 3 3 3 0 PINc domain ribonuclease zf-NADH-PPase PF09297.11 KXH41029.1 - 0.099 12.3 3.0 0.17 11.6 0.3 2.3 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Nop10p PF04135.12 KXH41030.1 - 5.3e-22 77.6 0.1 6e-22 77.4 0.1 1.0 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family DUF3328 PF11807.8 KXH41031.1 - 2e-19 70.3 0.4 2.1e-18 66.9 0.1 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF3328) NETI PF14044.6 KXH41032.1 - 0.00064 19.4 0.3 41 4.0 0.0 5.1 6 0 0 6 6 6 1 NETI protein DUF4794 PF16042.5 KXH41032.1 - 1.5 9.8 6.2 3.9 8.5 1.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4794) Bac_rhamnosid6H PF17389.2 KXH41033.1 - 5.7e-116 387.5 4.0 7.6e-116 387.1 4.0 1.2 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_N PF08531.10 KXH41033.1 - 5.7e-58 195.5 0.0 1.2e-57 194.5 0.0 1.5 1 0 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain Bac_rhamnosid PF05592.11 KXH41033.1 - 9.8e-33 112.2 0.0 2.4e-32 110.9 0.0 1.6 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase concanavalin-like domain Bac_rhamnosid_C PF17390.2 KXH41033.1 - 1.1e-19 69.9 0.6 2.1e-17 62.7 0.5 2.8 2 1 0 2 2 2 1 Bacterial alpha-L-rhamnosidase C-terminal domain MBD PF01429.19 KXH41033.1 - 0.079 12.7 0.0 2.1 8.1 0.0 2.9 3 0 0 3 3 3 0 Methyl-CpG binding domain SFTA2 PF15210.6 KXH41033.1 - 0.093 12.7 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 Surfactant-associated protein 2 adh_short PF00106.25 KXH41034.1 - 1.3e-34 119.3 0.0 2.6e-34 118.4 0.0 1.4 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXH41034.1 - 3.9e-25 88.8 0.0 5.1e-25 88.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH41034.1 - 2.9e-06 27.3 0.0 4.5e-05 23.4 0.0 2.0 1 1 1 2 2 2 1 KR domain DUF1776 PF08643.10 KXH41034.1 - 8.2e-06 25.4 0.1 1.1e-05 25.0 0.1 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) FA_desaturase PF00487.24 KXH41034.1 - 0.039 13.8 0.4 0.058 13.2 0.4 1.3 1 0 0 1 1 1 0 Fatty acid desaturase ADH_zinc_N PF00107.26 KXH41034.1 - 0.12 12.3 0.0 0.89 9.5 0.0 2.0 2 0 0 2 2 2 0 Zinc-binding dehydrogenase MFS_1 PF07690.16 KXH41035.1 - 1.3e-29 103.3 14.2 1e-16 60.8 0.6 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH41035.1 - 0.00025 20.0 4.4 0.00033 19.6 4.4 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.7 KXH41035.1 - 0.00028 19.9 10.2 0.00076 18.4 1.0 2.7 2 1 1 3 3 3 3 MFS_1 like family OATP PF03137.20 KXH41035.1 - 0.14 10.5 1.2 5.4 5.2 0.0 2.8 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family FA_hydroxylase PF04116.13 KXH41037.1 - 4e-22 79.0 9.9 4e-22 79.0 9.9 2.2 2 0 0 2 2 2 2 Fatty acid hydroxylase superfamily Peroxidase_2 PF01328.17 KXH41038.1 - 2.1e-50 171.9 0.1 2.5e-50 171.6 0.1 1.0 1 0 0 1 1 1 1 Peroxidase, family 2 PALP PF00291.25 KXH41040.1 - 3.3e-22 79.2 0.0 1.4e-16 60.8 0.0 2.0 1 1 1 2 2 2 2 Pyridoxal-phosphate dependent enzyme CoA_transf_3 PF02515.17 KXH41040.1 - 0.084 12.0 0.1 0.11 11.6 0.1 1.1 1 0 0 1 1 1 0 CoA-transferase family III PQQ_2 PF13360.6 KXH41040.1 - 0.12 11.9 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 PQQ-like domain bZIP_1 PF00170.21 KXH41041.1 - 0.0043 17.1 6.7 0.0089 16.1 6.7 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KXH41041.1 - 0.01 15.9 4.8 0.02 15.0 4.8 1.4 1 0 0 1 1 1 0 Basic region leucine zipper IFP_35_N PF07334.13 KXH41041.1 - 0.063 13.3 1.1 0.13 12.4 1.1 1.4 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus DUF3328 PF11807.8 KXH41042.1 - 1.8e-47 162.0 1.4 2.3e-47 161.6 1.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Seadorna_Vp10 PF07322.11 KXH41043.1 - 1.6 8.1 3.7 16 4.8 0.1 3.2 1 1 2 3 3 3 0 Seadornavirus Vp10 DUF4554 PF15091.6 KXH41043.1 - 9.3 5.0 6.6 12 4.7 6.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) DHDPS PF00701.22 KXH41044.1 - 4.2e-41 140.5 0.0 5.3e-41 140.2 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Fungal_trans_2 PF11951.8 KXH41045.1 - 5.7e-21 74.8 0.0 7.3e-21 74.4 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sugar_tr PF00083.24 KXH41046.1 - 1.6e-108 363.5 22.5 1.8e-108 363.3 22.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH41046.1 - 1.1e-24 87.1 46.4 1.5e-18 66.8 12.3 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily DUF3980 PF13140.6 KXH41046.1 - 1 9.8 5.8 36 4.9 0.3 3.9 2 1 1 3 3 3 0 Domain of unknown function (DUF3980) FA_desaturase PF00487.24 KXH41047.1 - 1.3e-13 51.4 27.0 2.1e-13 50.7 27.0 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Hydrolase_4 PF12146.8 KXH41050.1 - 1.8e-05 24.1 0.1 2.4e-05 23.7 0.1 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DLH PF01738.18 KXH41050.1 - 9.5e-05 22.0 0.1 0.00028 20.5 0.1 1.7 1 1 0 1 1 1 1 Dienelactone hydrolase family BAAT_C PF08840.11 KXH41050.1 - 0.00056 19.9 0.0 0.00086 19.3 0.0 1.3 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_6 PF12697.7 KXH41050.1 - 0.0042 17.7 0.5 0.0055 17.3 0.5 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KXH41050.1 - 0.0072 15.8 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.28 KXH41051.1 - 9.7e-78 262.3 0.0 1.4e-77 261.8 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXH41051.1 - 0.0042 17.0 0.4 0.018 14.9 0.4 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Endopep_inhib PF16800.5 KXH41051.1 - 0.017 15.1 0.1 0.07 13.1 0.1 1.9 2 0 0 2 2 2 0 IseA DL-endopeptidase inhibitor GFO_IDH_MocA PF01408.22 KXH41052.1 - 2.8e-13 50.7 0.1 5e-13 49.9 0.1 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NmrA PF05368.13 KXH41053.1 - 2.3e-18 66.6 1.6 1.8e-17 63.7 1.6 2.0 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXH41053.1 - 5e-13 49.3 0.4 4e-12 46.4 0.4 2.4 1 1 0 1 1 1 1 NAD(P)H-binding DapB_N PF01113.20 KXH41053.1 - 0.0076 16.4 0.2 0.023 14.8 0.2 1.9 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus KR PF08659.10 KXH41053.1 - 0.098 12.6 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 KR domain adh_short_C2 PF13561.6 KXH41054.1 - 6.3e-57 192.8 0.1 8.8e-57 192.3 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXH41054.1 - 1.7e-47 161.4 0.1 2.3e-47 161.0 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXH41054.1 - 1.7e-05 24.8 0.1 0.00021 21.2 0.1 2.0 1 1 0 1 1 1 1 KR domain FMO-like PF00743.19 KXH41055.1 - 8.2e-09 34.4 0.1 1.8e-08 33.3 0.1 1.5 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KXH41055.1 - 1.5e-08 34.3 0.0 2.1e-06 27.2 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXH41055.1 - 0.0091 15.3 0.0 1.1 8.4 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.19 KXH41056.1 - 3.4e-57 194.1 0.0 4.4e-57 193.7 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXH41056.1 - 1.2e-32 113.4 0.0 2.1e-32 112.6 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KXH41056.1 - 3.4e-07 29.7 0.1 0.019 14.1 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 KXH41056.1 - 0.00018 21.2 0.0 0.0053 16.4 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXH41056.1 - 0.00035 20.8 0.1 0.0012 19.0 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KXH41056.1 - 0.0051 16.1 0.0 0.011 14.9 0.0 1.5 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 KXH41056.1 - 0.015 14.4 0.0 0.025 13.6 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KXH41056.1 - 0.016 14.4 0.2 0.19 10.9 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXH41056.1 - 0.098 12.6 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding MFS_1 PF07690.16 KXH41057.1 - 2.6e-27 95.7 47.3 1.3e-26 93.4 26.4 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3302 PF11742.8 KXH41057.1 - 5.1 7.3 6.3 26 5.0 0.2 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF3302) DIOX_N PF14226.6 KXH41058.1 - 3.8e-20 72.8 0.0 8.2e-20 71.7 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KXH41058.1 - 1.8e-14 54.0 0.0 3.3e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TGS PF02824.21 KXH41058.1 - 0.05 13.7 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 TGS domain DIOX_N PF14226.6 KXH41059.1 - 7.9e-34 116.9 0.0 1.4e-33 116.2 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KXH41059.1 - 1.6e-13 51.0 0.0 3e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Peptidase_M6 PF05547.11 KXH41060.1 - 3.2e-07 29.1 0.2 0.0015 17.0 0.9 2.1 2 0 0 2 2 2 2 Immune inhibitor A peptidase M6 7TMR-DISMED2 PF07696.11 KXH41060.1 - 0.11 12.6 0.1 0.6 10.2 0.0 2.3 3 0 0 3 3 3 0 7TMR-DISM extracellular 2 Cellulase PF00150.18 KXH41061.1 - 7.4e-47 160.1 0.6 1.1e-46 159.5 0.6 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.18 KXH41061.1 - 1.4e-10 40.9 8.4 1.4e-10 40.9 8.4 2.5 2 0 0 2 2 2 1 Fungal cellulose binding domain DUF1699 PF08004.11 KXH41062.1 - 0.047 13.4 0.1 2 8.1 0.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1699) Peptidase_S41 PF03572.18 KXH41063.1 - 1.7e-07 30.9 0.0 3.5e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase family S41 GATase PF00117.28 KXH41064.1 - 7.6e-10 38.9 0.0 1.4e-09 38.1 0.0 1.4 2 0 0 2 2 2 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KXH41064.1 - 0.016 15.0 0.0 0.43 10.3 0.0 2.3 1 1 0 1 1 1 0 Peptidase C26 Zn_clus PF00172.18 KXH41065.1 - 2.1e-07 30.9 5.2 3.5e-07 30.2 5.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KXH41065.1 - 0.0058 15.5 1.5 0.0058 15.5 1.5 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain TetR_C_37 PF18665.1 KXH41065.1 - 0.19 12.3 0.0 0.43 11.2 0.0 1.5 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain MDM10 PF12519.8 KXH41066.1 - 9.1e-173 575.4 0.0 1e-172 575.2 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial distribution and morphology protein 10 Porin_3 PF01459.22 KXH41066.1 - 0.0053 16.3 0.0 2 7.8 0.0 2.5 2 0 0 2 2 2 2 Eukaryotic porin Zip PF02535.22 KXH41067.1 - 8.6e-58 196.1 9.6 9.9e-58 195.9 9.6 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter Ribosomal_S19e PF01090.19 KXH41068.1 - 1e-59 200.1 0.1 1.2e-59 200.0 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e HTH_8 PF02954.19 KXH41069.1 - 0.13 12.1 0.1 0.29 11.0 0.1 1.6 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family MFS_1 PF07690.16 KXH41070.1 - 3.1e-50 171.1 42.1 6.5e-49 166.7 27.8 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH41070.1 - 6.6e-13 48.3 7.0 6.6e-13 48.3 7.0 2.4 1 1 1 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KXH41070.1 - 3e-07 29.3 0.5 5.7e-07 28.3 0.5 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) 4HBT PF03061.22 KXH41071.1 - 1.4e-14 54.2 0.0 2.1e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily Zn_clus PF00172.18 KXH41072.1 - 1.8e-07 31.1 7.9 1.8e-07 31.1 7.9 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KXH41072.1 - 3.9e-06 25.9 0.6 3.8e-05 22.7 0.1 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Polysacc_deac_1 PF01522.21 KXH41075.1 - 1.4e-29 102.5 0.0 2.1e-29 101.9 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 KXH41075.1 - 0.0013 18.0 0.0 0.0077 15.5 0.0 1.8 1 1 0 2 2 2 1 Glycosyl hydrolase family 57 Glyco_hydro_114 PF03537.13 KXH41075.1 - 0.016 14.5 0.0 0.065 12.5 0.0 1.8 2 0 0 2 2 2 0 Glycoside-hydrolase family GH114 Glyco_hydro_18 PF00704.28 KXH41076.1 - 2.9e-67 227.6 0.1 3.3e-67 227.4 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF3142 PF11340.8 KXH41076.1 - 0.022 14.6 0.0 0.035 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3142) ZapC PF07126.12 KXH41076.1 - 0.16 11.6 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Cell-division protein ZapC Ricin_B_lectin PF00652.22 KXH41077.1 - 8.5e-15 55.1 0.1 1.6e-05 25.1 0.0 4.3 2 2 2 4 4 4 4 Ricin-type beta-trefoil lectin domain PUA_3 PF17785.1 KXH41077.1 - 0.1 12.4 0.1 2 8.3 0.0 2.6 2 0 0 2 2 2 0 PUA-like domain CDtoxinA PF03498.14 KXH41077.1 - 0.15 11.7 5.4 2.4 7.7 0.2 3.7 2 2 1 4 4 4 0 Cytolethal distending toxin A/C domain CorA PF01544.18 KXH41078.1 - 2.6e-28 99.2 10.8 3.5e-24 85.6 8.1 2.9 2 1 0 2 2 2 2 CorA-like Mg2+ transporter protein LapA_dom PF06305.11 KXH41078.1 - 0.0036 17.1 0.4 0.0078 16.0 0.4 1.6 1 0 0 1 1 1 1 Lipopolysaccharide assembly protein A domain DUF4282 PF14110.6 KXH41078.1 - 0.16 12.8 1.6 0.34 11.7 1.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4282) DUF4635 PF15466.6 KXH41081.1 - 0.072 12.6 0.2 0.12 11.9 0.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4635) CFEM PF05730.11 KXH41082.1 - 7e-07 29.2 1.7 1.4e-06 28.3 1.7 1.5 1 0 0 1 1 1 1 CFEM domain Ribosomal_S9 PF00380.19 KXH41083.1 - 9.6e-33 113.3 0.3 1.1e-32 113.1 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 EAP30 PF04157.16 KXH41084.1 - 5.7e-76 254.9 0.2 6.5e-76 254.7 0.2 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family Mpv17_PMP22 PF04117.12 KXH41085.1 - 2.1e-10 40.6 2.5 2.1e-10 40.6 2.5 2.2 3 0 0 3 3 3 1 Mpv17 / PMP22 family C1_2 PF03107.16 KXH41086.1 - 1.4 9.3 5.2 1 9.7 1.6 2.2 2 0 0 2 2 2 0 C1 domain PDH PF02153.17 KXH41087.1 - 1.4e-13 50.5 0.0 2.1e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase F420_oxidored PF03807.17 KXH41087.1 - 0.00074 20.1 0.6 0.013 16.1 0.6 2.4 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 KXH41087.1 - 0.035 14.3 2.0 0.38 10.9 2.0 2.4 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase RCC1 PF00415.18 KXH41088.1 - 2.6e-33 114.4 7.6 7.5e-11 42.5 0.0 7.3 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KXH41088.1 - 4.6e-19 67.7 20.8 2.4e-05 24.0 0.7 6.2 7 1 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat Rad9 PF04139.13 KXH41089.1 - 8.1e-47 159.8 0.0 1.1e-46 159.3 0.0 1.2 1 0 0 1 1 1 1 Rad9 LRR_4 PF12799.7 KXH41089.1 - 1.3 9.5 5.9 67 4.1 1.2 5.1 4 2 1 5 5 5 0 Leucine Rich repeats (2 copies) UCH PF00443.29 KXH41246.1 - 3.4e-67 226.6 0.0 1.2e-66 224.9 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KXH41246.1 - 6.2e-10 39.2 0.0 0.00012 21.8 0.0 3.2 3 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 KXH41246.1 - 2.4e-08 34.5 0.0 5.8e-08 33.3 0.0 1.7 1 0 0 1 1 1 1 DUSP domain zf-CHCC PF10276.9 KXH41247.1 - 2.3e-15 56.3 0.4 3.5e-15 55.8 0.4 1.3 1 0 0 1 1 1 1 Zinc-finger domain UPF0047 PF01894.17 KXH41248.1 - 1.8e-30 105.4 0.0 2.2e-30 105.1 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 NUDIX_2 PF13869.6 KXH41249.1 - 1.5e-80 269.2 0.0 1.8e-80 269.0 0.0 1.1 1 0 0 1 1 1 1 Nucleotide hydrolase Dynamin_N PF00350.23 KXH41250.1 - 5.7e-13 49.3 3.8 6.7e-13 49.0 0.0 2.8 3 0 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.23 KXH41250.1 - 3.6e-05 23.8 1.1 0.001 19.1 0.0 3.6 3 1 0 3 3 3 1 50S ribosome-binding GTPase ABC_tran PF00005.27 KXH41250.1 - 0.0004 20.9 0.1 0.0023 18.5 0.0 2.3 2 0 0 2 2 2 1 ABC transporter RsgA_GTPase PF03193.16 KXH41250.1 - 0.0055 16.6 0.0 0.02 14.8 0.0 2.0 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 KXH41250.1 - 0.015 15.7 0.9 0.48 10.8 0.0 3.6 3 1 1 4 4 4 0 AAA ATPase domain IIGP PF05049.13 KXH41250.1 - 0.027 13.5 0.1 0.079 12.0 0.0 1.8 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) T2SSE PF00437.20 KXH41250.1 - 0.04 13.0 0.0 0.085 11.9 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein KAP_NTPase PF07693.14 KXH41250.1 - 0.047 12.9 0.0 0.047 12.9 0.0 2.8 4 0 0 4 4 4 0 KAP family P-loop domain DUF1664 PF07889.12 KXH41250.1 - 0.057 13.5 1.2 10 6.2 1.2 3.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) AAA_29 PF13555.6 KXH41250.1 - 0.071 12.9 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain GTP-bdg_M PF16360.5 KXH41250.1 - 0.21 12.2 3.4 1.4 9.6 3.4 2.5 1 0 0 1 1 1 0 GTP-binding GTPase Middle Region Imm7 PF15585.6 KXH41250.1 - 0.29 11.4 2.3 11 6.3 0.2 3.5 3 1 0 3 3 3 0 Immunity protein 7 DUF87 PF01935.17 KXH41250.1 - 1.3 9.1 0.0 1.3 9.1 0.0 3.0 2 1 0 2 2 1 0 Helicase HerA, central domain DUF4140 PF13600.6 KXH41250.1 - 2.5 8.6 8.6 51 4.4 0.1 3.5 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF2968 PF11180.8 KXH41250.1 - 2.7 7.6 10.9 0.18 11.4 0.9 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2968) KxDL PF10241.9 KXH41250.1 - 8.3 6.8 8.3 38 4.6 0.1 3.2 2 0 0 2 2 2 0 Uncharacterized conserved protein DNA_pol_phi PF04931.13 KXH41251.1 - 4.8 5.2 4.6 8.1 4.4 4.6 1.3 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 KXH41251.1 - 6 6.1 5.3 14 4.9 5.3 1.6 1 0 0 1 1 1 0 NOA36 protein Pet100 PF09803.9 KXH41252.1 - 5.2e-12 46.1 5.9 5.5e-10 39.6 1.8 2.5 2 1 0 2 2 2 2 Pet100 Rbsn PF11464.8 KXH41252.1 - 0.086 12.6 0.2 0.16 11.7 0.2 1.4 1 0 0 1 1 1 0 Rabenosyn Rab binding domain Transcrip_reg PF01709.20 KXH41253.1 - 1.2e-59 201.6 3.0 5.4e-45 153.7 0.0 2.0 2 0 0 2 2 2 2 Transcriptional regulator HEAT_2 PF13646.6 KXH41254.1 - 2.9e-12 46.8 5.2 0.026 14.9 0.0 7.7 7 1 1 8 8 8 3 HEAT repeats Vac14_Fab1_bd PF12755.7 KXH41254.1 - 1.5e-06 28.7 0.0 0.077 13.6 0.0 4.8 4 0 0 4 4 4 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 KXH41254.1 - 0.00019 21.5 0.1 0.96 9.5 0.0 4.5 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 KXH41254.1 - 0.00023 21.6 12.2 3.9 8.1 0.1 7.7 7 1 1 8 8 8 2 HEAT-like repeat HEAT PF02985.22 KXH41254.1 - 0.00038 20.5 17.0 1 9.8 0.0 8.5 9 0 0 9 9 9 2 HEAT repeat CLASP_N PF12348.8 KXH41254.1 - 0.003 17.2 4.8 5.8 6.4 0.0 4.4 5 0 0 5 5 5 2 CLASP N terminal UNC45-central PF11701.8 KXH41254.1 - 0.011 15.7 0.6 1.4 8.9 0.0 4.4 3 1 1 4 4 4 0 Myosin-binding striated muscle assembly central V-ATPase_H_C PF11698.8 KXH41254.1 - 0.02 15.0 0.1 1.5 9.0 0.0 3.9 3 0 0 3 3 3 0 V-ATPase subunit H IFRD PF05004.13 KXH41254.1 - 0.54 9.3 10.1 2.5 7.1 0.3 5.3 4 1 1 5 5 5 0 Interferon-related developmental regulator (IFRD) PD40 PF07676.12 KXH41256.1 - 0.04 13.9 0.4 6.4 6.8 0.0 4.0 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Gmad1 PF10647.9 KXH41256.1 - 0.077 12.7 5.1 0.42 10.3 0.6 3.7 3 1 0 3 3 3 0 Lipoprotein LpqB beta-propeller domain WD40 PF00400.32 KXH41256.1 - 0.31 12.0 11.8 68 4.6 0.0 6.0 4 2 2 6 6 6 0 WD domain, G-beta repeat MoaC PF01967.21 KXH41257.1 - 5.5e-51 172.2 2.3 1.1e-50 171.2 2.3 1.6 1 0 0 1 1 1 1 MoaC family Mob_synth_C PF06463.13 KXH41257.1 - 9.4e-38 129.0 0.0 1e-36 125.7 0.0 2.2 1 1 1 2 2 2 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 KXH41257.1 - 8.3e-26 91.3 0.0 1.6e-25 90.4 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 KXH41257.1 - 0.00054 20.2 0.0 0.0013 19.0 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain GMC_oxred_N PF00732.19 KXH41258.1 - 2.9e-43 148.3 1.0 4e-43 147.9 1.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXH41258.1 - 3.1e-27 95.9 0.7 2.7e-26 92.8 0.0 2.6 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_3 PF01494.19 KXH41258.1 - 4.6e-06 26.1 0.1 7.3e-06 25.5 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KXH41258.1 - 1.1e-05 24.9 0.2 3.1e-05 23.4 0.2 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXH41258.1 - 1.8e-05 24.0 5.0 4.7e-05 22.7 5.0 1.7 1 1 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KXH41258.1 - 2.4e-05 23.7 0.6 0.0013 18.0 0.6 2.2 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 KXH41258.1 - 0.00032 20.8 3.5 0.00036 20.7 1.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KXH41258.1 - 0.0041 16.5 1.8 0.0068 15.8 1.8 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KXH41258.1 - 0.0062 15.3 0.7 0.009 14.8 0.2 1.5 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.24 KXH41258.1 - 0.012 15.2 5.2 0.21 11.1 5.2 2.2 1 1 0 1 1 1 0 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.14 KXH41258.1 - 0.025 14.2 1.4 0.041 13.4 1.4 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain GIDA PF01134.22 KXH41258.1 - 0.04 13.0 0.2 0.1 11.7 0.2 1.6 1 0 0 1 1 1 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 KXH41258.1 - 0.043 13.1 0.0 0.076 12.3 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GDI PF00996.18 KXH41258.1 - 0.049 12.1 0.0 0.075 11.5 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor Pyr_redox PF00070.27 KXH41258.1 - 0.062 13.9 0.2 0.14 12.8 0.2 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 KXH41258.1 - 0.067 13.1 0.1 0.14 12.0 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ThiF PF00899.21 KXH41258.1 - 0.14 11.4 0.1 0.28 10.5 0.1 1.4 1 0 0 1 1 1 0 ThiF family ELO PF01151.18 KXH41260.1 - 8.6e-83 277.7 10.6 1.1e-82 277.4 10.6 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family FYVE PF01363.21 KXH41261.1 - 1.7e-14 53.7 8.2 3e-14 52.9 8.2 1.4 1 0 0 1 1 1 1 FYVE zinc finger zf-AN1 PF01428.16 KXH41261.1 - 0.0035 17.5 5.2 0.0035 17.5 5.2 1.6 1 1 0 1 1 1 1 AN1-like Zinc finger ABC_tran PF00005.27 KXH41262.1 - 2.3e-40 138.3 0.0 6.8e-19 68.7 0.0 3.2 3 0 0 3 3 3 2 ABC transporter ABC_membrane PF00664.23 KXH41262.1 - 4.2e-27 95.5 27.2 1.1e-23 84.2 17.2 2.8 2 1 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.6 KXH41262.1 - 7.9e-11 42.3 5.0 0.0016 18.3 0.0 4.2 2 2 2 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KXH41262.1 - 2.1e-07 30.6 0.1 0.04 13.3 0.0 4.2 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KXH41262.1 - 6.5e-06 25.8 0.0 0.18 11.6 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.6 KXH41262.1 - 5.8e-05 22.8 0.0 0.31 10.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 KXH41262.1 - 0.00029 21.4 0.0 0.51 10.8 0.0 2.3 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 KXH41262.1 - 0.0003 20.9 0.1 0.64 10.1 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 KXH41262.1 - 0.00066 20.1 0.2 1.4 9.3 0.1 3.0 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 KXH41262.1 - 0.00092 19.5 0.0 1.6 9.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KXH41262.1 - 0.0026 17.7 0.0 2 8.3 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase T2SSE PF00437.20 KXH41262.1 - 0.0039 16.3 0.0 0.41 9.7 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein Dynamin_N PF00350.23 KXH41262.1 - 0.006 16.6 0.2 1.5 8.9 0.0 2.4 2 0 0 2 2 2 1 Dynamin family AAA_33 PF13671.6 KXH41262.1 - 0.0068 16.6 0.0 0.32 11.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 KXH41262.1 - 0.0076 16.0 0.0 2.5 7.7 0.1 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 KXH41262.1 - 0.0094 16.5 0.0 6.3 7.4 0.0 3.0 2 1 0 2 2 2 1 AAA domain DUF87 PF01935.17 KXH41262.1 - 0.016 15.3 0.1 0.035 14.2 0.1 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain cobW PF02492.19 KXH41262.1 - 0.018 14.6 0.3 2.2 7.8 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ATPase_2 PF01637.18 KXH41262.1 - 0.034 14.0 0.0 0.94 9.3 0.0 2.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea FtsK_SpoIIIE PF01580.18 KXH41262.1 - 0.036 13.4 0.0 4.1 6.7 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_7 PF12775.7 KXH41262.1 - 0.051 13.1 0.0 13 5.3 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region ABC_ATPase PF09818.9 KXH41262.1 - 0.11 11.2 0.1 0.99 8.1 0.0 2.1 2 0 0 2 2 2 0 Predicted ATPase of the ABC class Methyltransf_23 PF13489.6 KXH41264.1 - 2.7e-27 95.6 0.0 4e-17 62.5 0.0 3.3 2 1 1 3 3 3 2 Methyltransferase domain Methyltransf_25 PF13649.6 KXH41264.1 - 2.4e-15 57.0 0.0 9.4e-09 35.9 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 KXH41264.1 - 5e-13 49.1 0.0 8.6e-08 32.1 0.0 3.3 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 KXH41264.1 - 2.1e-11 44.4 0.0 4.3e-06 27.4 0.0 3.3 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 KXH41264.1 - 7.4e-10 39.4 0.0 2e-06 28.4 0.0 2.8 2 0 0 2 2 2 2 Methyltransferase domain MTS PF05175.14 KXH41264.1 - 1e-07 31.7 0.0 0.0085 15.7 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase small domain Methyltransf_2 PF00891.18 KXH41264.1 - 3e-06 26.7 0.0 0.061 12.6 0.0 2.7 2 0 0 2 2 2 2 O-methyltransferase domain FtsJ PF01728.19 KXH41264.1 - 3.2e-05 24.1 0.0 0.027 14.6 0.0 2.3 2 0 0 2 2 2 2 FtsJ-like methyltransferase Methyltransf_16 PF10294.9 KXH41264.1 - 7.2e-05 22.6 0.0 0.41 10.3 0.0 2.2 2 0 0 2 2 2 2 Lysine methyltransferase CMAS PF02353.20 KXH41264.1 - 0.00031 20.1 0.0 0.39 10.0 0.0 2.2 2 0 0 2 2 2 2 Mycolic acid cyclopropane synthetase DUF938 PF06080.12 KXH41264.1 - 0.00034 20.4 0.0 0.48 10.2 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF938) Methyltransf_4 PF02390.17 KXH41264.1 - 0.00059 19.3 0.1 0.57 9.6 0.0 2.4 2 0 0 2 2 2 2 Putative methyltransferase PrmA PF06325.13 KXH41264.1 - 0.0012 18.3 0.0 0.5 9.7 0.0 2.2 2 0 0 2 2 2 2 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.19 KXH41264.1 - 0.0013 18.6 0.0 2 8.1 0.0 2.3 2 0 0 2 2 2 2 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) GidB PF02527.15 KXH41264.1 - 0.12 11.7 0.0 32 3.8 0.0 2.9 3 0 0 3 3 3 0 rRNA small subunit methyltransferase G SnoaL PF07366.12 KXH41266.1 - 9.7e-07 28.6 0.1 0.013 15.3 0.1 2.8 2 1 0 2 2 2 2 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 KXH41266.1 - 9.9e-05 22.9 0.0 0.029 15.0 0.0 2.2 2 0 0 2 2 2 2 SnoaL-like domain Hemocyanin_N PF03722.14 KXH41266.1 - 0.12 12.9 0.1 0.19 12.2 0.1 1.3 1 0 0 1 1 1 0 Hemocyanin, all-alpha domain NERD PF08378.11 KXH41268.1 - 0.17 12.3 0.2 0.9 10.0 0.1 1.9 2 0 0 2 2 2 0 Nuclease-related domain VASt PF16016.5 KXH41270.1 - 1e-38 133.1 2.0 2.9e-38 131.7 2.0 1.8 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain BAR_3 PF16746.5 KXH41270.1 - 7.4e-17 61.8 0.0 1.3e-16 61.0 0.0 1.4 1 0 0 1 1 1 1 BAR domain of APPL family PH PF00169.29 KXH41270.1 - 2.5e-05 24.7 0.1 5.6e-05 23.6 0.1 1.6 1 0 0 1 1 1 1 PH domain DUF639 PF04842.12 KXH41270.1 - 0.01 15.3 1.0 0.021 14.3 1.0 1.4 1 0 0 1 1 1 0 Plant protein of unknown function (DUF639) GRAM PF02893.20 KXH41270.1 - 0.043 13.7 0.0 0.098 12.5 0.0 1.5 1 0 0 1 1 1 0 GRAM domain DUF3074 PF11274.8 KXH41271.1 - 1.2e-59 201.4 1.5 5.1e-58 196.1 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3074) Caldesmon PF02029.15 KXH41271.1 - 0.00015 20.7 26.1 0.00028 19.8 26.1 1.4 1 0 0 1 1 1 1 Caldesmon Spc7 PF08317.11 KXH41271.1 - 0.037 12.9 23.9 0.086 11.7 23.9 1.6 1 0 0 1 1 1 0 Spc7 kinetochore protein 17kDa_Anti_2 PF16998.5 KXH41271.1 - 0.75 9.7 3.3 0.62 10.0 0.6 2.3 2 1 0 2 2 2 0 17 kDa outer membrane surface antigen DUF2428 PF10350.9 KXH41272.1 - 5.9e-59 199.6 0.0 1.6e-58 198.2 0.0 1.8 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.22 KXH41272.1 - 6.8e-05 22.8 11.4 0.089 13.1 0.0 6.8 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.6 KXH41272.1 - 0.084 13.4 4.0 0.82 10.3 0.3 4.2 3 0 0 3 3 3 0 HEAT-like repeat Ribosomal_L1 PF00687.21 KXH41273.1 - 4.8e-45 153.8 0.1 5.6e-45 153.6 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family SNF PF00209.18 KXH41273.1 - 0.11 11.2 0.1 0.15 10.8 0.1 1.1 1 0 0 1 1 1 0 Sodium:neurotransmitter symporter family RNase_H PF00075.24 KXH41274.1 - 3e-21 76.1 0.0 5e-21 75.4 0.0 1.4 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.6 KXH41274.1 - 1.1e-05 25.2 0.2 0.00091 19.0 0.2 2.2 1 1 0 1 1 1 1 Reverse transcriptase-like YL1 PF05764.13 KXH41274.1 - 0.15 12.2 0.1 0.17 12.0 0.1 1.2 1 0 0 1 1 1 0 YL1 nuclear protein HEAT PF02985.22 KXH41275.1 - 0.0036 17.4 4.5 7 7.2 0.0 5.3 6 0 0 6 6 6 2 HEAT repeat Nitr_red_assoc PF09655.10 KXH41275.1 - 0.0045 17.6 1.6 1.4 9.5 0.1 3.1 3 0 0 3 3 3 2 Conserved nitrate reductase-associated protein (Nitr_red_assoc) HEAT_2 PF13646.6 KXH41275.1 - 0.0058 17.0 1.8 0.61 10.5 0.1 4.3 4 0 0 4 4 4 1 HEAT repeats HEAT_EZ PF13513.6 KXH41275.1 - 0.008 16.7 2.0 0.29 11.7 0.0 4.5 5 0 0 5 5 5 1 HEAT-like repeat F_actin_bind PF08919.10 KXH41275.1 - 0.042 14.0 2.7 1.2 9.2 0.0 3.9 5 0 0 5 5 5 0 F-actin binding Cnd1 PF12717.7 KXH41275.1 - 0.094 12.8 3.6 0.74 9.8 0.1 4.2 5 2 0 5 5 5 0 non-SMC mitotic condensation complex subunit 1 DUF4854 PF16146.5 KXH41276.1 - 9.8 6.6 8.8 0.87 9.9 1.3 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4854) FGGY_C PF02782.16 KXH41277.1 - 1.2e-27 97.0 0.0 1.5e-27 96.6 0.0 1.1 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 KXH41277.1 - 2.3e-05 24.1 0.0 3.1e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain ANAPC_CDC26 PF10471.9 KXH41293.1 - 0.0023 18.7 0.1 0.0023 18.7 0.1 3.0 3 0 0 3 3 3 1 Anaphase-promoting complex APC subunit CDC26 TT1725 PF18324.1 KXH41295.1 - 0.053 13.6 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Hypothetical protein TT1725 GEN1_C PF18380.1 KXH41296.1 - 1.9e-27 96.2 0.1 1.1e-26 93.7 0.0 2.4 2 0 0 2 2 2 1 Holliday junction resolvase Gen1 C-terminal domain XPG_I PF00867.18 KXH41296.1 - 6.1e-26 90.6 0.0 1.2e-25 89.7 0.0 1.5 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.7 KXH41296.1 - 0.076 12.5 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 XPG domain containing Actin PF00022.19 KXH41297.1 - 3.7e-19 68.6 0.0 9.8e-18 63.9 0.0 2.5 1 1 0 1 1 1 1 Actin VP_N-CPKC PF11475.8 KXH41297.1 - 0.22 11.5 0.3 0.49 10.4 0.3 1.5 1 0 0 1 1 1 0 Virion protein N terminal domain tRNA-synt_2b PF00587.25 KXH41298.1 - 8.2e-19 68.3 0.0 1.5e-18 67.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 KXH41298.1 - 2.4e-11 43.8 5.0 5.3e-11 42.7 5.0 1.6 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain SOGA PF11365.8 KXH41298.1 - 0.13 13.4 1.2 7.4 7.8 0.4 2.8 2 1 1 3 3 3 0 Protein SOGA DUF2730 PF10805.8 KXH41299.1 - 0.012 15.7 0.9 0.012 15.7 0.9 7.8 5 3 2 7 7 7 0 Protein of unknown function (DUF2730) E2R135 PF11570.8 KXH41299.1 - 0.021 15.1 4.6 0.11 12.7 0.1 3.6 2 1 0 2 2 2 0 Coiled-coil receptor-binding R-domain of colicin E2 DUF5511 PF17630.2 KXH41299.1 - 0.24 11.6 9.7 24 5.2 0.2 5.4 1 1 5 6 6 6 0 Family of unknown function (DUF5511) Iron_permease PF04120.12 KXH41299.1 - 0.69 9.7 10.2 0.14 11.9 0.5 5.1 3 2 2 5 5 5 0 Low affinity iron permease Vps4_C PF09336.10 KXH41299.1 - 6.8 6.8 10.7 21 5.2 0.1 5.6 5 2 0 6 6 6 0 Vps4 C terminal oligomerisation domain TruB_C PF09142.11 KXH41300.1 - 0.03 14.1 1.7 0.072 12.9 1.7 1.7 1 0 0 1 1 1 0 tRNA Pseudouridine synthase II, C terminal ATG27 PF09451.10 KXH41301.1 - 1.1e-100 336.9 1.2 2.7e-100 335.6 0.0 2.0 2 0 0 2 2 2 1 Autophagy-related protein 27 Spt20 PF12090.8 KXH41301.1 - 3.1e-57 193.9 0.0 3.1e-57 193.9 0.0 4.7 2 1 2 4 4 4 1 Spt20 family Cutinase PF01083.22 KXH41303.1 - 4.3e-46 157.1 2.8 5.1e-46 156.9 2.8 1.1 1 0 0 1 1 1 1 Cutinase DUF2974 PF11187.8 KXH41303.1 - 0.02 14.4 0.1 0.033 13.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) TPIP1 PF15338.6 KXH41303.1 - 0.08 13.0 1.0 0.14 12.2 0.2 1.8 1 1 1 2 2 2 0 p53-regulated apoptosis-inducing protein 1 Palm_thioest PF02089.15 KXH41303.1 - 0.091 12.6 0.2 0.099 12.5 0.2 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase SnoaL_2 PF12680.7 KXH41305.1 - 0.00015 22.3 0.0 0.00023 21.8 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_3 PF13474.6 KXH41305.1 - 0.0009 19.5 0.0 0.0012 19.0 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 KXH41305.1 - 0.009 16.4 0.0 0.017 15.5 0.0 1.6 1 1 1 2 2 2 1 Domain of unknown function (DUF4440) Ribosomal_S7 PF00177.21 KXH41305.1 - 0.035 13.7 0.0 0.056 13.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein S7p/S5e CaMKII_AD PF08332.10 KXH41305.1 - 0.051 13.7 0.0 0.074 13.2 0.0 1.3 1 0 0 1 1 1 0 Calcium/calmodulin dependent protein kinase II association domain Aminotran_3 PF00202.21 KXH41306.1 - 2.3e-114 382.2 0.0 3.1e-114 381.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 KXH41306.1 - 2.9e-05 23.4 0.1 0.00011 21.6 0.0 2.0 2 1 0 2 2 2 1 Aminotransferase class I and II HET PF06985.11 KXH41307.1 - 1.9e-35 122.4 2.9 1.9e-35 122.4 2.9 1.9 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) HET PF06985.11 KXH41308.1 - 5e-36 124.2 0.8 1e-35 123.2 0.8 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Abhydrolase_3 PF07859.13 KXH41309.1 - 1.9e-33 116.1 0.0 8.9e-24 84.5 0.0 2.5 2 0 0 2 2 2 2 alpha/beta hydrolase fold Lipase_3 PF01764.25 KXH41309.1 - 0.076 12.9 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) A_deaminase PF00962.22 KXH41310.1 - 6.2e-74 249.2 0.0 7.1e-74 249.1 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase TRM PF02005.16 KXH41310.1 - 0.05 12.8 0.0 0.068 12.3 0.0 1.1 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase MIF4G PF02854.19 KXH41344.1 - 1.7e-51 174.9 0.0 2.7e-51 174.2 0.0 1.4 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.8 KXH41344.1 - 4.8e-23 81.1 1.2 1.1e-22 79.9 1.2 1.7 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 DUF4148 PF13663.6 KXH41344.1 - 0.0044 17.2 0.6 1.5 9.1 0.0 3.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4148) DNA_pol_B PF00136.21 KXH41345.1 - 2.5e-118 395.7 0.2 3.6e-118 395.2 0.2 1.2 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.10 KXH41345.1 - 1.4e-69 233.6 0.8 2.6e-69 232.7 0.8 1.5 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.19 KXH41345.1 - 3.7e-42 144.7 0.0 8.2e-42 143.5 0.0 1.6 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.8 KXH41345.1 - 2.5e-23 81.9 10.1 2.5e-23 81.9 10.1 2.4 3 0 0 3 3 3 1 DNA polymerase alpha subunit p180 N terminal DNA_pol_B_2 PF03175.13 KXH41345.1 - 0.006 15.5 0.1 0.022 13.6 0.0 1.9 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral PPR_2 PF13041.6 KXH41346.1 - 1.9e-21 76.0 1.1 1.2e-13 51.0 0.0 5.3 5 1 1 6 6 6 2 PPR repeat family PPR PF01535.20 KXH41346.1 - 1e-07 31.7 6.0 1.7 9.0 0.0 7.2 8 1 0 8 8 8 3 PPR repeat PPR_3 PF13812.6 KXH41346.1 - 1.3e-06 28.4 0.8 0.008 16.2 0.0 4.1 3 1 1 4 4 4 3 Pentatricopeptide repeat domain PPR_long PF17177.4 KXH41346.1 - 1.7e-06 27.6 1.3 9.3e-06 25.1 0.3 2.4 2 0 0 2 2 2 1 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 KXH41346.1 - 0.00026 20.6 1.4 1.4 8.7 0.0 5.7 6 0 0 6 6 6 1 PPR repeat TPR_14 PF13428.6 KXH41346.1 - 0.0076 17.0 3.7 1.2 10.1 0.1 4.2 4 0 0 4 4 3 1 Tetratricopeptide repeat Zw10 PF06248.13 KXH41346.1 - 0.027 13.1 0.5 0.059 11.9 0.5 1.5 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 CCAP PF11105.8 KXH41346.1 - 0.064 13.2 1.1 1.8 8.5 0.0 3.0 3 0 0 3 3 3 0 Arthropod cardioacceleratory peptide 2a aGPT-Pplase3 PF18746.1 KXH41346.1 - 0.088 12.1 1.1 6.1 6.1 0.1 3.1 3 0 0 3 3 3 0 Alpha-glutamyl/putrescinyl thymine pyrophosphorylase clade 3 ATP13 PF12921.7 KXH41346.1 - 0.096 12.5 0.6 2.5 8.0 0.0 2.9 3 0 0 3 3 3 0 Mitochondrial ATPase expression Plk4_PB2 PF18409.1 KXH41346.1 - 7.6 7.3 6.4 1.6e+02 3.0 0.0 4.1 3 1 1 4 4 4 0 Polo-like Kinase 4 Polo Box 2 RRM_1 PF00076.22 KXH41347.1 - 0.079 12.8 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_pol_I_A49 PF06870.12 KXH41348.1 - 0.0039 16.1 2.8 0.015 14.2 2.8 1.8 1 1 0 1 1 1 1 A49-like RNA polymerase I associated factor Pkinase PF00069.25 KXH41349.1 - 1.1e-50 172.5 0.1 3.8e-50 170.7 0.1 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXH41349.1 - 2.5e-23 82.7 0.0 5e-23 81.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXH41349.1 - 0.00032 20.7 2.4 0.00034 20.6 0.1 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 KXH41349.1 - 0.0027 17.3 0.2 0.0073 15.9 0.2 1.6 1 1 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 KXH41349.1 - 0.58 9.7 2.3 0.39 10.3 0.2 1.8 2 0 0 2 2 2 0 Choline/ethanolamine kinase Epimerase PF01370.21 KXH41352.1 - 3.7e-17 62.6 0.1 5.7e-17 62.0 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KXH41352.1 - 1.2e-10 41.6 6.3 1.7e-08 34.6 2.7 2.9 1 1 1 2 2 2 2 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KXH41352.1 - 3.6e-10 39.8 0.0 5.4e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KXH41352.1 - 8.6e-09 34.8 0.0 1.2e-08 34.3 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KXH41352.1 - 3.5e-06 26.4 0.7 2.3e-05 23.7 0.7 2.0 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.13 KXH41352.1 - 1.2e-05 25.0 0.2 2.9e-05 23.7 0.2 1.7 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.15 KXH41352.1 - 0.00059 19.1 0.0 0.00086 18.5 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein MoCF_biosynth PF00994.24 KXH41352.1 - 0.044 13.5 0.0 0.17 11.6 0.0 1.9 2 0 0 2 2 2 0 Probable molybdopterin binding domain Glyco_trans_4_4 PF13579.6 KXH41352.1 - 0.13 12.6 4.4 1.4 9.4 0.3 2.5 1 1 0 2 2 2 0 Glycosyl transferase 4-like domain adh_short PF00106.25 KXH41352.1 - 0.15 11.5 1.3 4.3 6.7 0.0 2.4 2 1 0 2 2 2 0 short chain dehydrogenase DUF1206 PF06724.11 KXH41353.1 - 3.3 7.9 7.6 26 5.0 0.6 3.4 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1206) Cupin_2 PF07883.11 KXH41355.1 - 2.6e-22 78.3 0.6 1.3e-18 66.5 0.2 2.4 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.19 KXH41355.1 - 0.00044 20.2 0.2 0.001 19.0 0.2 1.6 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_3 PF05899.12 KXH41355.1 - 0.007 16.0 0.0 0.085 12.6 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF861) Cupin_1 PF00190.22 KXH41355.1 - 0.0083 15.7 0.0 0.094 12.3 0.0 2.1 2 0 0 2 2 2 1 Cupin FAA_hydrolase PF01557.18 KXH41356.1 - 3.4e-63 213.2 0.0 4.1e-63 213.0 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Fungal_trans PF04082.18 KXH41357.1 - 8.3e-24 84.0 0.6 1.2e-23 83.6 0.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH41357.1 - 5e-08 32.9 10.0 7.9e-08 32.3 10.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.24 KXH41358.1 - 7.9e-89 298.6 20.1 9.2e-89 298.4 20.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH41358.1 - 1.2e-34 119.8 35.2 3.4e-31 108.4 24.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Zn_clus PF00172.18 KXH41359.1 - 4e-10 39.7 7.4 8e-10 38.7 7.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain COesterase PF00135.28 KXH41360.1 - 5.1e-81 273.1 0.0 1.2e-70 238.9 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 KXH41360.1 - 9.4e-08 32.2 0.3 4.9e-07 29.8 0.3 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold NACHT PF05729.12 KXH41362.1 - 6.7e-08 32.6 0.0 1.7e-07 31.3 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KXH41362.1 - 4.3e-05 24.0 1.4 0.00076 19.9 0.0 3.2 4 0 0 4 4 4 1 AAA ATPase domain AAA_22 PF13401.6 KXH41362.1 - 0.0037 17.6 0.0 0.025 14.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 KXH41362.1 - 0.015 15.2 0.3 0.25 11.2 0.0 2.4 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea AAA PF00004.29 KXH41362.1 - 0.029 14.8 0.0 0.21 12.0 0.0 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 KXH41362.1 - 0.038 13.7 0.0 0.088 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain SesA PF17107.5 KXH41362.1 - 0.038 14.2 0.8 0.55 10.4 0.1 2.9 2 1 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases AAA_18 PF13238.6 KXH41362.1 - 0.047 14.2 0.0 0.14 12.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KXH41362.1 - 0.068 13.6 0.1 0.16 12.4 0.1 1.6 1 0 0 1 1 1 0 RNA helicase AAA_29 PF13555.6 KXH41362.1 - 0.089 12.6 0.0 0.28 11.0 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 KXH41362.1 - 0.12 12.9 0.0 0.5 10.9 0.0 2.0 1 0 0 1 1 1 0 ABC transporter HicA_toxin PF07927.12 KXH41363.1 - 0.08 13.0 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 HicA toxin of bacterial toxin-antitoxin, DAAD PF18752.1 KXH41365.1 - 0.043 13.7 2.1 0.079 12.8 2.1 1.5 1 0 0 1 1 1 0 Dictyosteliid AID/APOBEC-like Deaminase Glycos_transf_2 PF00535.26 KXH41366.1 - 4.5e-26 91.7 0.0 7.4e-26 91.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KXH41366.1 - 5.7e-08 32.9 0.1 1.7e-06 28.1 0.0 2.5 2 1 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 KXH41366.1 - 0.00016 21.3 0.0 0.00024 20.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 KXH41366.1 - 0.017 15.6 0.0 0.034 14.6 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 SE PF08491.10 KXH41367.1 - 5.5e-86 288.0 0.0 7.1e-86 287.7 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase DAO PF01266.24 KXH41367.1 - 4.1e-10 39.8 0.3 6.6e-07 29.2 0.4 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KXH41367.1 - 6.9e-09 35.4 1.0 2.7e-06 26.9 0.1 2.3 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KXH41367.1 - 2.6e-05 24.4 0.5 5.9e-05 23.2 0.5 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 KXH41367.1 - 0.00011 21.4 1.2 0.00027 20.1 1.2 1.6 1 1 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.17 KXH41367.1 - 0.00012 21.4 0.0 0.00021 20.6 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 KXH41367.1 - 0.0023 18.4 1.8 0.12 12.9 0.2 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXH41367.1 - 0.0028 16.9 0.2 0.013 14.8 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXH41367.1 - 0.0034 16.5 0.3 0.005 16.0 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KXH41367.1 - 0.0035 16.7 1.3 0.005 16.2 0.2 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase ApbA PF02558.16 KXH41367.1 - 0.0076 15.9 0.1 0.013 15.2 0.1 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.23 KXH41367.1 - 0.0097 15.9 0.0 0.016 15.2 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.18 KXH41367.1 - 0.053 13.4 0.1 0.093 12.6 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 KXH41367.1 - 0.06 12.4 0.1 0.11 11.5 0.1 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein HI0933_like PF03486.14 KXH41367.1 - 0.061 12.0 0.1 0.093 11.4 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Shikimate_DH PF01488.20 KXH41367.1 - 0.14 12.3 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase AAA PF00004.29 KXH41368.1 - 2.9e-53 179.8 0.0 3.8e-39 134.1 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KXH41368.1 - 1.2e-09 37.8 0.3 1.3e-06 28.1 0.0 2.9 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 KXH41368.1 - 3.7e-06 27.4 2.4 0.022 15.2 0.6 3.9 1 1 2 3 3 3 2 AAA ATPase domain AAA_5 PF07728.14 KXH41368.1 - 1.1e-05 25.5 0.0 0.11 12.5 0.0 3.6 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) Vps4_C PF09336.10 KXH41368.1 - 2.4e-05 24.3 0.0 0.13 12.3 0.0 3.0 3 0 0 3 3 3 2 Vps4 C terminal oligomerisation domain AAA_14 PF13173.6 KXH41368.1 - 0.00011 22.2 0.0 0.08 13.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain CDC48_N PF02359.18 KXH41368.1 - 0.00034 20.7 0.0 0.022 14.9 0.0 2.6 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), N-terminal domain AAA_22 PF13401.6 KXH41368.1 - 0.00037 20.8 1.2 0.58 10.4 0.4 3.8 2 2 1 3 3 3 1 AAA domain AAA_25 PF13481.6 KXH41368.1 - 0.00066 19.3 0.9 0.14 11.8 0.0 3.1 2 2 1 3 3 3 1 AAA domain AAA_33 PF13671.6 KXH41368.1 - 0.0013 18.9 0.0 0.15 12.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KXH41368.1 - 0.0016 18.7 0.0 0.075 13.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KXH41368.1 - 0.0059 17.0 0.0 5.1 7.5 0.0 2.8 2 0 0 2 2 2 1 RNA helicase RuvB_N PF05496.12 KXH41368.1 - 0.018 14.8 0.0 0.1 12.4 0.0 2.3 2 1 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain Torsin PF06309.11 KXH41368.1 - 0.07 13.2 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 Torsin Rad17 PF03215.15 KXH41368.1 - 0.07 13.0 0.0 0.21 11.5 0.0 1.8 2 0 0 2 2 2 0 Rad17 P-loop domain DUF815 PF05673.13 KXH41368.1 - 0.1 11.8 0.0 0.38 9.9 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 KXH41368.1 - 0.17 11.4 0.3 7.7 6.0 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region Nop10p PF04135.12 KXH41369.1 - 0.084 12.9 0.2 0.2 11.7 0.2 1.6 1 0 0 1 1 1 0 Nucleolar RNA-binding protein, Nop10p family Ras PF00071.22 KXH41370.1 - 2.6e-64 215.7 0.0 3e-64 215.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXH41370.1 - 7.5e-34 116.5 0.0 1.3e-33 115.8 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXH41370.1 - 4.2e-13 49.1 0.0 4.7e-13 49.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KXH41370.1 - 1e-05 25.2 0.0 2.2e-05 24.1 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KXH41370.1 - 0.00028 20.3 0.0 0.0003 20.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KXH41370.1 - 0.0022 18.1 0.0 0.0066 16.5 0.0 1.7 1 1 1 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KXH41370.1 - 0.005 16.8 0.2 2.6 7.9 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 KXH41370.1 - 0.027 13.9 0.0 0.033 13.6 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 KXH41370.1 - 0.05 13.1 0.0 0.25 10.9 0.0 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_22 PF13401.6 KXH41370.1 - 0.13 12.6 0.1 0.47 10.7 0.1 2.0 1 1 0 1 1 1 0 AAA domain NCA2 PF08637.10 KXH41371.1 - 1.3e-111 372.4 0.1 2e-111 371.8 0.1 1.3 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 TMEM171 PF15471.6 KXH41371.1 - 0.22 10.5 0.1 0.36 9.8 0.1 1.2 1 0 0 1 1 1 0 Transmembrane protein family 171 FCD PF07729.12 KXH41371.1 - 0.34 11.4 2.3 0.64 10.5 0.7 2.3 2 0 0 2 2 2 0 FCD domain FA_hydroxylase PF04116.13 KXH41372.1 - 9e-26 90.8 15.8 9e-26 90.8 15.8 2.1 2 1 1 3 3 3 1 Fatty acid hydroxylase superfamily Pterin_4a PF01329.19 KXH41373.1 - 3.1e-09 36.9 0.1 0.00014 22.0 0.1 2.3 1 1 1 2 2 2 2 Pterin 4 alpha carbinolamine dehydratase KAR PF15222.6 KXH41373.1 - 0.056 13.7 0.5 0.4 11.0 0.3 2.0 2 0 0 2 2 2 0 Kidney androgen-regulated Amidohydro_1 PF01979.20 KXH41374.1 - 4.9e-36 124.7 0.0 6.2e-36 124.4 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KXH41374.1 - 2.4e-09 37.2 3.7 6.3e-08 32.5 0.3 2.3 2 0 0 2 2 2 2 Amidohydrolase family DUF3606 PF12244.8 KXH41374.1 - 0.018 14.9 0.4 0.044 13.7 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3606) bZIP_1 PF00170.21 KXH41375.1 - 3.3e-09 36.7 6.9 8e-09 35.5 6.9 1.6 1 0 0 1 1 1 1 bZIP transcription factor Fib_alpha PF08702.10 KXH41375.1 - 0.16 12.1 1.1 0.29 11.3 1.1 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family bZIP_2 PF07716.15 KXH41375.1 - 0.59 10.3 9.0 18 5.5 9.0 2.6 1 1 0 1 1 1 0 Basic region leucine zipper Actin PF00022.19 KXH41376.1 - 1.8e-57 194.8 0.0 1.3e-33 116.2 0.0 2.3 2 0 0 2 2 2 2 Actin DASH_Dad4 PF08650.10 KXH41377.1 - 3.7e-33 113.3 8.2 4e-33 113.2 8.2 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad4 Biotin_carb_C PF02785.19 KXH41377.1 - 0.028 14.5 0.1 0.031 14.4 0.1 1.1 1 0 0 1 1 1 0 Biotin carboxylase C-terminal domain CD34_antigen PF06365.12 KXH41377.1 - 0.04 13.5 0.4 0.042 13.4 0.4 1.1 1 0 0 1 1 1 0 CD34/Podocalyxin family GM_CSF PF01109.17 KXH41377.1 - 0.055 13.6 0.5 0.062 13.5 0.5 1.1 1 0 0 1 1 1 0 Granulocyte-macrophage colony-stimulating factor DASH_Dad1 PF08649.10 KXH41377.1 - 0.45 10.7 5.2 0.73 10.1 5.2 1.4 1 1 0 1 1 1 0 DASH complex subunit Dad1 YL1_C PF08265.11 KXH41378.1 - 1.4e-15 56.8 0.2 2.2e-15 56.1 0.2 1.3 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Got1 PF04178.12 KXH41379.1 - 3.6e-15 56.4 11.6 4.5e-15 56.0 11.6 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family DUF373 PF04123.13 KXH41379.1 - 1.1 8.7 3.1 0.71 9.3 2.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF373) Profilin PF00235.19 KXH41380.1 - 9.9e-44 148.7 1.0 1.1e-43 148.5 1.0 1.0 1 0 0 1 1 1 1 Profilin Synaptobrevin PF00957.21 KXH41382.1 - 2.7e-14 52.7 0.5 4e-14 52.2 0.5 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 KXH41382.1 - 1.1e-12 47.8 0.0 2.3e-12 46.8 0.0 1.6 1 1 0 1 1 1 1 Regulated-SNARE-like domain Sec63 PF02889.16 KXH41383.1 - 4.4e-139 461.9 0.0 7e-82 274.4 0.0 2.2 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 KXH41383.1 - 1.1e-49 168.6 0.2 9.2e-26 90.7 0.4 3.4 4 0 0 4 4 4 2 DEAD/DEAH box helicase ResIII PF04851.15 KXH41383.1 - 1.6e-21 77.1 0.0 7.9e-11 42.2 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KXH41383.1 - 6.6e-15 55.4 0.1 2.5e-06 27.8 0.0 4.6 3 2 0 3 3 3 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 KXH41383.1 - 4.3e-07 30.3 0.1 0.039 14.2 0.0 3.7 2 2 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KXH41383.1 - 6.5e-06 26.0 0.1 0.033 13.9 0.2 2.4 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 KXH41383.1 - 3.2e-05 24.3 0.6 0.008 16.5 0.5 2.6 2 0 0 2 2 2 1 AAA domain Helicase_PWI PF18149.1 KXH41383.1 - 5.4e-05 23.3 0.0 0.00013 22.1 0.0 1.6 1 0 0 1 1 1 1 N-terminal helicase PWI domain AAA PF00004.29 KXH41383.1 - 0.013 15.9 0.2 4.3 7.8 0.0 3.5 2 2 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 KXH41383.1 - 0.022 13.8 0.0 1.2 8.1 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein TniB PF05621.11 KXH41383.1 - 0.19 11.1 1.0 21 4.5 0.1 3.6 4 0 0 4 4 4 0 Bacterial TniB protein Ras PF00071.22 KXH41384.1 - 8.2e-40 136.1 0.0 1.6e-37 128.6 0.0 2.1 2 0 0 2 2 2 2 Ras family Roc PF08477.13 KXH41384.1 - 2.4e-31 108.5 0.0 3.5e-31 107.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXH41384.1 - 5.2e-11 42.3 0.0 8.2e-11 41.7 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KXH41384.1 - 2e-05 24.7 0.0 3.6e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 KXH41384.1 - 0.0047 16.4 0.0 0.0069 15.8 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Herpes_TAF50 PF03326.13 KXH41384.1 - 0.017 13.8 0.4 0.022 13.4 0.4 1.1 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) RTP1_C2 PF10304.9 KXH41384.1 - 0.15 11.8 0.3 0.27 10.9 0.3 1.4 1 0 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 2 Gtr1_RagA PF04670.12 KXH41384.1 - 0.21 10.9 0.0 0.33 10.3 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region DUF1929 PF09118.11 KXH41385.1 - 2.3e-22 79.1 0.0 5.2e-22 78.0 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) PAN_1 PF00024.26 KXH41385.1 - 4.4e-15 55.4 8.2 5.5e-08 32.7 1.5 2.3 2 0 0 2 2 2 2 PAN domain Kelch_6 PF13964.6 KXH41385.1 - 1.7e-14 53.5 0.0 0.00093 19.4 0.0 3.9 3 0 0 3 3 3 3 Kelch motif Kelch_1 PF01344.25 KXH41385.1 - 1.1e-11 44.0 0.3 0.0005 19.6 0.1 4.3 3 1 0 3 3 3 2 Kelch motif Kelch_2 PF07646.15 KXH41385.1 - 8.1e-10 38.3 0.0 0.0085 16.0 0.0 4.8 4 1 0 4 4 4 3 Kelch motif Kelch_4 PF13418.6 KXH41385.1 - 3.3e-08 33.4 8.2 0.024 14.6 0.1 6.2 5 2 0 5 5 5 2 Galactose oxidase, central domain Glyoxal_oxid_N PF07250.11 KXH41385.1 - 8.2e-07 28.5 0.0 0.019 14.2 0.0 2.9 2 1 1 3 3 3 2 Glyoxal oxidase N-terminus PAN_4 PF14295.6 KXH41385.1 - 8.1e-05 22.4 8.7 0.036 14.0 0.9 2.7 2 0 0 2 2 2 2 PAN domain MANEC PF07502.14 KXH41385.1 - 0.0058 16.9 7.1 0.56 10.5 0.5 2.4 2 0 0 2 2 2 2 MANEC domain Kelch_3 PF13415.6 KXH41385.1 - 0.051 13.9 0.0 3.8 7.9 0.0 3.4 3 0 0 3 3 3 0 Galactose oxidase, central domain PAN_3 PF08277.12 KXH41385.1 - 0.48 10.3 9.9 4.3 7.2 2.1 2.4 2 0 0 2 2 2 0 PAN-like domain PSDC PF12588.8 KXH41386.1 - 1.9e-37 128.3 0.0 3.2e-37 127.6 0.0 1.3 1 0 0 1 1 1 1 Phophatidylserine decarboxylase PS_Dcarbxylase PF02666.15 KXH41386.1 - 1e-28 100.2 0.0 1.4e-28 99.8 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase FMN_dh PF01070.18 KXH41387.1 - 6.5e-120 400.3 0.1 8e-120 400.0 0.1 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 KXH41387.1 - 3.3e-22 78.4 0.1 6.7e-22 77.4 0.1 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 KXH41387.1 - 3.3e-07 29.8 0.1 6.4e-07 28.8 0.1 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 KXH41387.1 - 0.00027 20.0 2.5 0.00088 18.4 0.2 2.3 3 0 0 3 3 3 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 KXH41387.1 - 0.0022 17.4 0.5 0.0038 16.6 0.5 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase His_biosynth PF00977.21 KXH41387.1 - 0.014 14.9 1.4 0.53 9.7 0.1 2.3 1 1 0 2 2 2 0 Histidine biosynthesis protein G3P_antiterm PF04309.12 KXH41387.1 - 0.029 13.8 0.1 0.27 10.6 0.0 2.1 2 0 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator ThiG PF05690.14 KXH41387.1 - 0.061 12.6 0.1 7.7 5.7 0.1 2.2 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG DUF561 PF04481.12 KXH41387.1 - 0.077 12.2 0.1 0.62 9.2 0.0 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF561) UPF0257 PF06788.13 KXH41387.1 - 0.16 11.8 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0257) DUF2116 PF09889.9 KXH41388.1 - 0.17 11.9 1.4 0.31 11.0 1.4 1.3 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Ank_2 PF12796.7 KXH41389.1 - 5.3e-25 87.8 0.3 5.5e-11 42.9 0.0 3.8 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXH41389.1 - 4.8e-21 74.9 0.4 0.00012 22.5 0.0 6.5 4 2 2 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXH41389.1 - 1.7e-13 49.4 2.2 0.0072 16.7 0.0 6.5 6 0 0 6 6 6 3 Ankyrin repeat Ank PF00023.30 KXH41389.1 - 7.7e-12 45.1 0.6 0.71 10.4 0.0 5.8 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 KXH41389.1 - 1.3e-10 41.3 1.9 0.011 16.1 0.0 5.1 4 1 2 6 6 6 3 Ankyrin repeats (many copies) NACHT PF05729.12 KXH41389.1 - 4.1e-09 36.6 0.0 9.2e-09 35.4 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KXH41389.1 - 2.4e-05 24.8 0.2 0.0002 21.8 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain DUF1843 PF08898.10 KXH41389.1 - 0.0083 16.6 0.0 0.27 11.8 0.0 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF1843) KAP_NTPase PF07693.14 KXH41389.1 - 0.023 14.0 1.8 0.12 11.6 0.7 2.1 1 1 1 2 2 2 0 KAP family P-loop domain Adeno_E3_15_3 PF03307.14 KXH41389.1 - 0.14 12.1 0.0 0.32 11.0 0.0 1.5 1 0 0 1 1 1 0 Adenovirus 15.3kD protein in E3 region BRO1 PF03097.18 KXH41391.1 - 4.1e-129 430.8 0.9 4.1e-129 430.8 0.9 2.2 3 0 0 3 3 3 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 KXH41391.1 - 5.3e-80 268.9 18.9 9.8e-80 268.0 18.9 1.5 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV DUF416 PF04222.12 KXH41391.1 - 4.7 6.6 10.7 1.8 7.9 0.4 3.7 3 2 1 4 4 4 0 Protein of unknown function (DUF416) COG2 PF06148.11 KXH41391.1 - 8.5 6.5 12.3 0.31 11.1 1.5 3.4 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DnaJ_C PF01556.18 KXH41392.1 - 1.6e-38 132.1 0.0 2.4e-38 131.6 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KXH41392.1 - 1.5e-23 82.7 0.7 2.7e-23 81.9 0.7 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KXH41392.1 - 1.2e-09 38.3 21.5 2.5e-09 37.4 21.5 1.6 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.19 KXH41392.1 - 5.1 7.2 7.3 35 4.5 7.5 2.2 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Anti-TRAP PF15777.5 KXH41392.1 - 6.2 6.9 17.6 1.1 9.3 2.7 3.1 2 1 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein SAP30_Sin3_bdg PF13867.6 KXH41393.1 - 1.7e-09 37.8 2.2 3.5e-08 33.7 0.3 2.4 2 0 0 2 2 2 2 Sin3 binding region of histone deacetylase complex subunit SAP30 Fungal_trans PF04082.18 KXH41394.1 - 3e-68 229.8 0.0 4.1e-68 229.3 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KXH41394.1 - 9.8e-05 22.6 13.3 0.00031 21.0 0.7 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KXH41394.1 - 0.015 15.7 1.1 0.015 15.7 1.1 3.2 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 KXH41394.1 - 0.057 14.3 0.7 0.057 14.3 0.7 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger F-box-like PF12937.7 KXH41395.1 - 2.2e-07 30.7 0.1 9.9e-07 28.6 0.0 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KXH41395.1 - 5.3e-07 29.4 0.0 1.2e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 F-box domain 4HBT PF03061.22 KXH41396.1 - 3e-12 46.7 0.0 4.2e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 KXH41396.1 - 3.6e-06 27.4 0.0 5.4e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily Pex2_Pex12 PF04757.14 KXH41397.1 - 1.4e-50 171.9 3.3 1.8e-50 171.6 3.3 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.6 KXH41397.1 - 0.0025 17.9 3.9 0.0042 17.2 3.9 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 KXH41397.1 - 0.027 14.8 3.3 0.045 14.1 3.3 1.3 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_3 PF13920.6 KXH41397.1 - 0.036 13.9 1.7 0.054 13.4 1.7 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXH41397.1 - 0.067 13.0 3.0 0.11 12.3 3.0 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXH41397.1 - 0.2 11.6 2.5 0.34 10.8 2.5 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXH41397.1 - 0.31 11.1 2.7 0.54 10.3 2.7 1.5 1 0 0 1 1 1 0 RING-type zinc-finger Glyco_hydro_16 PF00722.21 KXH41398.1 - 1.9e-06 27.4 0.0 7.6e-06 25.5 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 WSC PF01822.19 KXH41398.1 - 0.012 15.8 0.8 0.026 14.7 0.0 2.0 2 0 0 2 2 2 0 WSC domain DUF4971 PF16341.5 KXH41398.1 - 0.062 13.1 1.7 0.15 11.9 1.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4971) Metallophos PF00149.28 KXH41399.1 - 7e-12 46.3 0.8 1e-11 45.7 0.8 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KXH41399.1 - 2.1e-05 24.8 0.5 0.00022 21.5 0.5 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Anoctamin PF04547.12 KXH41400.1 - 7.7e-117 390.9 10.6 9.4e-117 390.6 10.6 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel SH3_9 PF14604.6 KXH41401.1 - 6.4e-09 35.5 0.1 1.5e-08 34.3 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain Avl9 PF09794.9 KXH41402.1 - 1.1e-125 419.3 0.3 3e-124 414.6 0.3 2.6 1 1 0 1 1 1 1 Transport protein Avl9 SPA PF08616.10 KXH41402.1 - 0.00017 21.5 0.0 0.00035 20.5 0.0 1.5 1 0 0 1 1 1 1 Stabilization of polarity axis Pkinase PF00069.25 KXH41403.1 - 1.9e-68 230.7 0.0 2.5e-68 230.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXH41403.1 - 3.5e-32 111.7 0.0 4.7e-32 111.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KXH41403.1 - 9.2e-06 24.8 0.1 1.3e-05 24.4 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KXH41403.1 - 3.3e-05 23.4 0.1 0.0001 21.7 0.1 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXH41403.1 - 0.00043 20.3 0.1 0.0018 18.3 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KXH41403.1 - 0.00083 18.7 0.0 0.05 12.9 0.0 2.2 1 1 1 2 2 2 1 Kinase-like RIO1 PF01163.22 KXH41403.1 - 0.021 14.4 0.0 0.037 13.6 0.0 1.4 1 0 0 1 1 1 0 RIO1 family FTA2 PF13095.6 KXH41403.1 - 0.024 14.3 0.0 0.046 13.3 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 VP_N-CPKC PF11475.8 KXH41404.1 - 0.083 12.8 0.3 0.15 12.0 0.3 1.4 1 0 0 1 1 1 0 Virion protein N terminal domain Glyco_hydro_43 PF04616.14 KXH41407.1 - 2.9e-48 164.7 0.7 4.4e-48 164.1 0.7 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 CBM_6 PF03422.15 KXH41407.1 - 2.6e-38 131.1 1.8 2.6e-38 131.1 1.8 1.9 2 0 0 2 2 2 1 Carbohydrate binding module (family 6) DUF5010_C PF18099.1 KXH41407.1 - 2.8e-07 30.7 0.3 5e-07 29.8 0.3 1.4 1 0 0 1 1 1 1 DUF5010 C-terminal domain Glyco_hydro_32N PF00251.20 KXH41407.1 - 0.0013 18.3 1.5 0.0028 17.3 1.5 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain VirJ PF06057.11 KXH41408.1 - 0.2 11.5 0.0 0.32 10.8 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Fungal_trans_2 PF11951.8 KXH41409.1 - 3.5e-41 141.3 0.0 4.4e-41 141.0 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH41409.1 - 5e-05 23.3 15.7 0.0001 22.3 15.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Thioredoxin PF00085.20 KXH41410.1 - 1.2e-23 83.0 0.2 2.4e-23 82.0 0.2 1.5 1 0 0 1 1 1 1 Thioredoxin Ank_2 PF12796.7 KXH41410.1 - 2.9e-10 40.6 2.5 0.028 15.0 0.0 5.6 3 1 2 5 5 5 3 Ankyrin repeats (3 copies) Patatin PF01734.22 KXH41410.1 - 1.4e-06 28.7 0.0 3.1e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase NACHT PF05729.12 KXH41410.1 - 6e-06 26.3 0.1 5.4e-05 23.2 0.0 2.4 1 1 1 2 2 2 1 NACHT domain OST3_OST6 PF04756.13 KXH41410.1 - 0.00018 21.0 0.0 0.0003 20.2 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Ank_4 PF13637.6 KXH41410.1 - 0.00022 21.7 0.1 2.6 8.7 0.0 4.6 4 0 0 4 4 4 1 Ankyrin repeats (many copies) AAA_16 PF13191.6 KXH41410.1 - 0.00026 21.4 0.6 0.001 19.5 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain Thioredoxin_8 PF13905.6 KXH41410.1 - 0.00033 20.9 0.0 0.0011 19.3 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_7 PF13899.6 KXH41410.1 - 0.0064 16.7 0.0 0.019 15.1 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin-like Ank_3 PF13606.6 KXH41410.1 - 0.011 16.2 0.2 0.29 11.8 0.0 3.5 3 0 0 3 3 3 0 Ankyrin repeat Thioredoxin_2 PF13098.6 KXH41410.1 - 0.014 15.9 0.0 0.035 14.6 0.0 1.7 1 0 0 1 1 1 0 Thioredoxin-like domain KAP_NTPase PF07693.14 KXH41410.1 - 0.017 14.4 0.6 2.4 7.3 0.4 2.4 1 1 1 2 2 2 0 KAP family P-loop domain AAA_22 PF13401.6 KXH41410.1 - 0.027 14.7 0.2 0.68 10.2 0.0 3.0 2 1 0 3 3 3 0 AAA domain Redoxin PF08534.10 KXH41410.1 - 0.03 14.1 0.1 0.084 12.6 0.1 1.7 1 0 0 1 1 1 0 Redoxin AhpC-TSA PF00578.21 KXH41410.1 - 0.03 14.2 0.1 0.1 12.5 0.0 1.9 2 0 0 2 2 2 0 AhpC/TSA family Ank PF00023.30 KXH41410.1 - 0.05 14.1 1.4 0.74 10.4 0.0 3.4 3 0 0 3 3 3 0 Ankyrin repeat Ank_5 PF13857.6 KXH41410.1 - 0.053 13.9 1.1 13 6.3 0.0 3.3 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Glutaredoxin PF00462.24 KXH41410.1 - 0.061 13.6 0.0 0.24 11.6 0.0 2.1 1 0 0 1 1 1 0 Glutaredoxin DAO PF01266.24 KXH41411.1 - 2.4e-34 119.5 0.7 2.7e-34 119.3 0.7 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXH41411.1 - 0.00032 20.9 0.1 0.00067 19.8 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KXH41411.1 - 0.0035 16.6 0.1 0.0035 16.6 0.1 1.6 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 KXH41411.1 - 0.0042 16.2 0.0 0.0066 15.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KXH41411.1 - 0.022 14.0 0.0 0.034 13.4 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXH41411.1 - 0.041 14.5 0.1 0.1 13.2 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KXH41411.1 - 0.19 10.5 0.1 0.36 9.6 0.1 1.4 2 0 0 2 2 2 0 Tryptophan halogenase HI0933_like PF03486.14 KXH41411.1 - 0.22 10.2 0.1 0.34 9.5 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein ALG3 PF05208.13 KXH41412.1 - 1.5e-148 495.1 14.7 1.7e-148 494.8 14.7 1.0 1 0 0 1 1 1 1 ALG3 protein eIF-1a PF01176.19 KXH41413.1 - 1.5e-20 72.7 0.2 2.1e-20 72.3 0.2 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Terminase_6 PF03237.15 KXH41413.1 - 0.054 13.1 0.0 0.062 13.0 0.0 1.1 1 0 0 1 1 1 0 Terminase-like family MFS_1 PF07690.16 KXH41414.1 - 2e-24 86.2 74.7 9.7e-20 70.8 45.1 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily LapA_dom PF06305.11 KXH41414.1 - 0.97 9.3 4.9 5.6 6.9 1.1 3.2 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain MFS_3 PF05977.13 KXH41414.1 - 2.1 6.6 18.1 0.64 8.3 1.9 2.6 1 1 2 3 3 3 0 Transmembrane secretion effector HAD PF12710.7 KXH41415.1 - 5.6e-23 82.3 0.0 7.4e-23 81.9 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.12 KXH41415.1 - 0.0064 16.0 0.0 0.014 14.9 0.0 1.5 1 1 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) Hydrolase PF00702.26 KXH41415.1 - 0.0069 16.7 0.2 0.21 11.8 0.2 2.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Ins_allergen_rp PF06757.13 KXH41415.1 - 0.14 12.2 0.0 0.43 10.5 0.0 1.8 2 0 0 2 2 2 0 Insect allergen related repeat, nitrile-specifier detoxification She9_MDM33 PF05546.11 KXH41416.1 - 2.1e-81 272.5 6.8 3.1e-81 271.9 6.8 1.3 1 0 0 1 1 1 1 She9 / Mdm33 family SOG2 PF10428.9 KXH41416.1 - 0.0099 15.1 23.2 0.016 14.4 23.2 1.3 1 0 0 1 1 1 1 RAM signalling pathway protein Citrate_synt PF00285.21 KXH41416.1 - 0.048 12.7 5.1 0.11 11.5 4.7 2.0 1 1 0 1 1 1 0 Citrate synthase, C-terminal domain Macoilin PF09726.9 KXH41416.1 - 0.058 12.0 9.1 0.12 10.9 9.1 1.5 1 0 0 1 1 1 0 Macoilin family PsbH PF00737.20 KXH41416.1 - 0.072 12.8 0.3 0.14 11.9 0.3 1.4 1 0 0 1 1 1 0 Photosystem II 10 kDa phosphoprotein NAM-associated PF14303.6 KXH41416.1 - 0.21 12.3 9.9 0.08 13.7 5.3 2.7 2 1 0 2 2 2 0 No apical meristem-associated C-terminal domain BST2 PF16716.5 KXH41416.1 - 0.54 10.9 10.6 0.22 12.1 6.2 2.5 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 Peptidase_S64 PF08192.11 KXH41416.1 - 7.4 4.9 7.7 10 4.5 7.7 1.2 1 0 0 1 1 1 0 Peptidase family S64 Pkinase PF00069.25 KXH41417.1 - 7.4e-60 202.5 0.0 1.3e-59 201.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXH41417.1 - 4e-35 121.3 0.0 7.3e-35 120.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.16 KXH41417.1 - 1e-21 76.8 19.9 5.6e-12 45.6 4.5 2.9 2 0 0 2 2 2 2 Hr1 repeat C1_1 PF00130.22 KXH41417.1 - 9.7e-20 70.2 31.5 4.7e-12 45.6 11.4 2.4 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.24 KXH41417.1 - 3e-14 53.4 1.0 1.2e-13 51.6 1.0 2.1 1 0 0 1 1 1 1 Protein kinase C terminal domain C2 PF00168.30 KXH41417.1 - 0.00019 21.7 0.0 0.00036 20.8 0.0 1.4 1 0 0 1 1 1 1 C2 domain DUF3895 PF13034.6 KXH41417.1 - 0.12 12.4 0.0 2.9 8.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3895) PAT1 PF09770.9 KXH41417.1 - 0.14 10.4 13.5 0.29 9.3 13.5 1.5 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Kinase-like PF14531.6 KXH41417.1 - 0.14 11.4 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 Kinase-like zf-RING_9 PF13901.6 KXH41417.1 - 2.4 8.1 22.6 2.3 8.1 7.5 2.5 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon Acyl-CoA_dh_1 PF00441.24 KXH41418.1 - 4.3e-40 137.4 4.0 8.1e-40 136.5 4.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KXH41418.1 - 2.4e-29 102.3 0.3 5.4e-29 101.1 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KXH41418.1 - 3.5e-23 81.6 0.0 6.9e-23 80.7 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KXH41418.1 - 5.4e-18 65.6 0.5 1e-17 64.6 0.5 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 KXH41418.1 - 0.00051 19.8 0.0 0.0013 18.4 0.0 1.6 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal AgrD PF05931.11 KXH41418.1 - 0.025 14.6 0.2 0.07 13.2 0.0 1.8 2 0 0 2 2 2 0 Staphylococcal AgrD protein Ribosom_S12_S23 PF00164.25 KXH41419.1 - 3.2e-29 100.9 0.6 4.2e-29 100.5 0.6 1.2 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Glyco_transf_15 PF01793.16 KXH41420.1 - 3e-140 467.1 5.6 3.7e-140 466.8 5.6 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Ribosomal_L32e PF01655.18 KXH41420.1 - 0.061 13.7 0.2 0.38 11.2 0.1 2.1 2 0 0 2 2 2 0 Ribosomal protein L32 PAT1 PF09770.9 KXH41421.1 - 0 1360.4 1.7 0 1360.2 1.7 1.0 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 T3SS_needle_F PF09392.10 KXH41421.1 - 2.6 8.3 4.9 0.31 11.3 0.2 1.9 2 0 0 2 2 2 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF Sin_N PF04801.13 KXH41422.1 - 6.7e-24 84.9 0.0 1.7e-23 83.6 0.0 1.6 1 1 0 1 1 1 1 Sin-like protein conserved region GIY-YIG PF01541.24 KXH41424.1 - 0.0043 17.3 0.0 0.01 16.1 0.0 1.7 1 0 0 1 1 1 1 GIY-YIG catalytic domain MFS_1 PF07690.16 KXH41425.1 - 5.7e-33 114.3 26.1 5.1e-31 107.9 25.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_holin_5_1 PF06946.11 KXH41425.1 - 0.21 12.0 2.7 7 7.1 0.1 2.8 2 0 0 2 2 2 0 Bacteriophage A118-like holin, Hol118 DUF4231 PF14015.6 KXH41425.1 - 4.1 7.9 6.2 1 9.9 0.4 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) HORMA PF02301.18 KXH41426.1 - 7.6e-12 45.3 0.0 9.9e-12 44.9 0.0 1.1 1 0 0 1 1 1 1 HORMA domain DUF3455 PF11937.8 KXH41426.1 - 0.12 12.8 0.0 0.16 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3455) PI31_Prot_N PF11566.8 KXH41427.1 - 1.6e-53 180.9 0.0 5e-53 179.2 0.0 1.7 1 1 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.11 KXH41427.1 - 1.9e-18 67.4 19.7 1.9e-18 67.4 19.7 2.8 3 1 0 3 3 3 1 PI31 proteasome regulator Mannosidase_ig PF17786.1 KXH41428.1 - 2.5e-12 47.2 0.1 8.5e-12 45.5 0.1 1.9 1 0 0 1 1 1 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 KXH41428.1 - 1.9e-09 38.1 0.1 5.5e-09 36.7 0.1 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_C PF02836.17 KXH41428.1 - 0.0085 15.2 0.0 0.015 14.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Peptidase_S9 PF00326.21 KXH41429.1 - 3.8e-44 150.7 0.0 5.9e-44 150.1 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family PD40 PF07676.12 KXH41429.1 - 0.00027 20.8 0.7 0.16 12.0 0.0 3.0 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat AXE1 PF05448.12 KXH41429.1 - 0.00084 18.1 0.2 0.079 11.6 0.2 2.6 2 1 0 2 2 2 1 Acetyl xylan esterase (AXE1) Abhydrolase_1 PF00561.20 KXH41429.1 - 0.0017 18.0 0.6 0.21 11.2 0.8 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 KXH41429.1 - 0.0047 16.8 0.0 0.78 9.6 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold EAP30 PF04157.16 KXH41431.1 - 3.4e-42 144.4 0.1 4.5e-42 144.0 0.1 1.2 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36-NZF-N PF16988.5 KXH41431.1 - 1.3e-22 78.9 10.9 2.7e-22 77.9 2.5 2.9 2 1 0 2 2 2 2 Vacuolar protein sorting 36 NZF-N zinc-finger domain Vps36_ESCRT-II PF11605.8 KXH41431.1 - 6.7e-14 51.8 0.0 1.2e-13 51.0 0.0 1.3 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 zf-Sec23_Sec24 PF04810.15 KXH41431.1 - 0.0002 21.4 2.6 0.024 14.7 0.2 2.5 2 0 0 2 2 2 2 Sec23/Sec24 zinc finger zf-RanBP PF00641.18 KXH41431.1 - 0.00079 18.7 1.9 0.00079 18.7 1.9 2.6 3 0 0 3 3 3 2 Zn-finger in Ran binding protein and others GRAM PF02893.20 KXH41431.1 - 0.0056 16.6 0.0 0.0099 15.8 0.0 1.3 1 0 0 1 1 1 1 GRAM domain DUF35_N PF12172.8 KXH41431.1 - 0.28 11.1 1.5 0.83 9.6 1.5 1.8 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) DZR PF12773.7 KXH41431.1 - 1 9.5 7.2 0.077 13.0 0.9 2.2 2 1 0 2 2 2 0 Double zinc ribbon SAC3_GANP PF03399.16 KXH41432.1 - 7e-24 84.7 1.6 7.7e-22 78.0 1.6 2.1 1 1 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 KXH41432.1 - 0.038 14.0 0.0 0.082 12.9 0.0 1.5 1 0 0 1 1 1 0 CSN8/PSMD8/EIF3K family HV_small_capsid PF17086.5 KXH41433.1 - 0.27 11.5 0.7 0.42 10.9 0.1 1.6 1 1 1 2 2 2 0 Small capsid protein of Herpesviridae MCPVI PF02993.14 KXH41433.1 - 0.29 10.9 3.1 0.33 10.7 3.1 1.1 1 0 0 1 1 1 0 Minor capsid protein VI SH3_1 PF00018.28 KXH41435.1 - 6.6e-27 92.9 0.0 3e-13 49.1 0.0 2.6 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 KXH41435.1 - 1.7e-18 66.2 0.1 3.4e-09 36.4 0.1 2.9 2 0 0 2 2 2 2 Variant SH3 domain PX PF00787.24 KXH41435.1 - 4.3e-13 49.2 0.0 8.1e-13 48.4 0.0 1.4 1 0 0 1 1 1 1 PX domain SH3_2 PF07653.17 KXH41435.1 - 1.9e-12 46.7 0.0 1.5e-07 31.0 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain PB1 PF00564.24 KXH41435.1 - 2.9e-08 33.5 0.1 5.3e-08 32.7 0.1 1.4 1 0 0 1 1 1 1 PB1 domain Rad60-SLD PF11976.8 KXH41435.1 - 0.096 12.5 0.2 0.72 9.7 0.2 2.3 1 1 1 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like Pex14_N PF04695.13 KXH41435.1 - 1.1 9.9 18.1 6.5 7.4 1.0 3.3 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region HTH_ABP1_N PF18107.1 KXH41436.1 - 1.5e-24 85.4 1.7 4.6e-24 83.9 1.7 1.8 1 0 0 1 1 1 1 Fission yeast centromere protein N-terminal domain HTH_Tnp_Tc5 PF03221.16 KXH41436.1 - 4.5e-18 65.0 1.2 3.7e-17 62.1 0.1 2.6 2 1 1 3 3 3 1 Tc5 transposase DNA-binding domain DUF4604 PF15377.6 KXH41436.1 - 0.031 14.7 0.1 0.053 13.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) DUF2868 PF11067.8 KXH41436.1 - 6.2 6.2 8.2 36 3.7 8.2 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2868) Thymidylat_synt PF00303.19 KXH41437.1 - 1.1e-109 365.8 0.0 1.2e-109 365.6 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase SGL PF08450.12 KXH41439.1 - 1.7e-10 40.9 0.0 3.7e-10 39.8 0.0 1.5 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 KXH41439.1 - 0.0034 17.5 0.0 0.0083 16.3 0.0 1.6 1 0 0 1 1 1 1 Arylesterase NHL PF01436.21 KXH41439.1 - 0.015 15.3 0.6 4.5 7.5 0.0 3.3 3 0 0 3 3 3 0 NHL repeat adh_short PF00106.25 KXH41440.1 - 3.6e-25 88.6 0.2 6.5e-25 87.7 0.2 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXH41440.1 - 2.2e-15 56.8 0.1 2.8e-15 56.5 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH41440.1 - 7.7e-07 29.2 0.1 9.5e-07 28.9 0.1 1.2 1 0 0 1 1 1 1 KR domain ATP19 PF11022.8 KXH41441.1 - 1.7e-28 98.8 0.0 1.9e-28 98.6 0.0 1.0 1 0 0 1 1 1 1 ATP synthase subunit K MTP18 PF10558.9 KXH41442.1 - 4.6e-82 274.1 0.1 5.8e-82 273.7 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) zf-AN1 PF01428.16 KXH41443.1 - 3.4e-24 84.7 25.4 2.5e-12 46.7 6.3 2.2 2 0 0 2 2 2 2 AN1-like Zinc finger IBR PF01485.21 KXH41443.1 - 0.0074 16.5 3.5 0.0074 16.5 3.5 2.8 2 1 0 2 2 2 1 IBR domain, a half RING-finger domain DpnI PF06044.12 KXH41443.1 - 1.4 8.5 3.3 2.5 7.7 0.5 2.2 2 0 0 2 2 2 0 Dam-replacing family Remorin_C PF03763.13 KXH41443.1 - 1.4 8.8 5.9 0.16 11.9 1.5 1.7 2 0 0 2 2 2 0 Remorin, C-terminal region Transp_Tc5_C PF04236.15 KXH41443.1 - 1.6 9.1 16.2 1.8 9.0 7.0 2.3 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain zf-C3HC4_2 PF13923.6 KXH41443.1 - 3.9 7.4 16.3 0.24 11.3 1.2 3.2 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Rad4 PF03835.15 KXH41444.1 - 2.1e-34 118.3 0.0 8e-34 116.4 0.0 2.1 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.9 KXH41444.1 - 3e-26 91.6 0.4 6.1e-26 90.6 0.4 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 KXH41444.1 - 7.7e-18 64.1 0.1 1.8e-17 62.9 0.1 1.7 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 KXH41444.1 - 4.8e-17 62.7 0.7 4.8e-17 62.7 0.7 6.8 6 1 0 6 6 6 2 Rad4 beta-hairpin domain 2 Transglut_core PF01841.19 KXH41444.1 - 0.0022 18.4 0.1 0.013 15.9 0.1 2.6 1 1 0 1 1 1 1 Transglutaminase-like superfamily DNA_pol_B_N PF18094.1 KXH41444.1 - 0.27 11.8 1.4 27 5.4 0.3 2.9 2 0 0 2 2 2 0 DNA polymerase beta N-terminal domain IBR PF01485.21 KXH41445.1 - 0.087 13.1 29.3 0.035 14.3 9.7 3.2 3 0 0 3 3 3 0 IBR domain, a half RING-finger domain Dcc1 PF09724.9 KXH41446.1 - 2.3e-11 43.6 0.1 2.6e-11 43.4 0.1 1.0 1 0 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 RhoGEF PF00621.20 KXH41447.1 - 1.2e-27 97.3 1.6 4e-27 95.6 0.1 2.2 2 0 0 2 2 2 1 RhoGEF domain DUF3507 PF12015.8 KXH41447.1 - 0.039 13.7 0.0 0.079 12.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3507) MRP-S31 PF15433.6 KXH41447.1 - 0.26 10.9 6.4 0.6 9.7 6.4 1.6 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 CdvA PF18822.1 KXH41447.1 - 0.55 10.1 14.6 2.5 8.0 1.8 3.5 1 1 2 3 3 3 0 CdvA-like coiled-coil domain T4SS PF07996.11 KXH41447.1 - 1.2 9.5 4.2 13 6.2 0.1 3.0 3 0 0 3 3 3 0 Type IV secretion system proteins Rab5-bind PF09311.11 KXH41447.1 - 2.6 7.3 13.1 0.36 10.2 6.6 2.3 1 1 1 2 2 2 0 Rabaptin-like protein ECH_2 PF16113.5 KXH41447.1 - 3.5 7.0 9.1 0.98 8.8 1.2 2.8 3 0 0 3 3 3 0 Enoyl-CoA hydratase/isomerase IBN_N PF03810.19 KXH41448.1 - 3.2e-10 39.8 0.2 5.4e-09 35.9 0.1 2.8 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.12 KXH41448.1 - 0.003 17.6 0.0 8.4 6.4 0.0 3.9 4 0 0 4 4 4 2 Exportin 1-like protein CAS_CSE1 PF03378.15 KXH41448.1 - 0.016 13.8 0.0 0.027 13.0 0.0 1.4 1 0 0 1 1 1 0 CAS/CSE protein, C-terminus HEAT PF02985.22 KXH41448.1 - 0.024 14.9 0.1 9.9 6.7 0.0 4.1 3 0 0 3 3 3 0 HEAT repeat Ribosomal_60s PF00428.19 KXH41448.1 - 0.075 13.6 3.3 0.23 12.1 3.3 1.8 1 0 0 1 1 1 0 60s Acidic ribosomal protein Ion_trans PF00520.31 KXH41449.1 - 4.3e-10 39.2 26.7 9.5e-10 38.1 26.7 1.5 1 0 0 1 1 1 1 Ion transport protein RTA1 PF04479.13 KXH41450.1 - 5.5e-50 169.8 9.2 7.2e-50 169.5 9.2 1.1 1 0 0 1 1 1 1 RTA1 like protein Renin_r PF07850.14 KXH41450.1 - 0.1 13.2 2.9 0.12 13.0 0.2 2.3 2 0 0 2 2 2 0 Renin receptor-like protein MIG-14_Wnt-bd PF06664.12 KXH41450.1 - 1.9 7.6 8.5 5.6 6.1 8.5 1.8 1 1 0 1 1 1 0 Wnt-binding factor required for Wnt secretion Apt1 PF10351.9 KXH41451.1 - 0.0007 18.6 5.8 0.00089 18.2 5.8 1.1 1 0 0 1 1 1 1 Golgi-body localisation protein domain EphA2_TM PF14575.6 KXH41451.1 - 0.2 12.6 0.0 7.6 7.5 0.0 2.4 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Presenilin PF01080.17 KXH41451.1 - 0.97 8.1 4.8 1.4 7.6 4.8 1.1 1 0 0 1 1 1 0 Presenilin CPSF100_C PF13299.6 KXH41451.1 - 0.98 9.6 4.0 1.6 8.9 4.0 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Pex14_N PF04695.13 KXH41451.1 - 1.5 9.4 9.4 4 8.1 9.4 1.7 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PH_12 PF16457.5 KXH41451.1 - 2.7 8.5 9.5 5 7.7 9.5 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain DUF572 PF04502.13 KXH41451.1 - 3.4 7.2 6.9 4.8 6.7 6.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF4614 PF15391.6 KXH41451.1 - 4 7.4 22.5 7.2 6.6 22.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Macoilin PF09726.9 KXH41451.1 - 10 4.6 19.4 14 4.1 19.4 1.1 1 0 0 1 1 1 0 Macoilin family PALP PF00291.25 KXH41452.1 - 3.3e-74 249.9 8.6 3.8e-74 249.7 8.6 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CMAS PF02353.20 KXH41453.1 - 5.1e-61 206.4 0.2 6.3e-61 206.1 0.2 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.12 KXH41453.1 - 1.9e-07 31.6 0.0 3.5e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXH41453.1 - 2.8e-07 30.5 0.0 4.4e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH41453.1 - 1.3e-06 29.1 0.0 2.6e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 KXH41453.1 - 0.018 14.6 0.0 0.032 13.7 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 PCMT PF01135.19 KXH41453.1 - 0.025 14.3 0.0 0.042 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 KXH41453.1 - 0.027 14.0 0.0 0.055 13.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain HET PF06985.11 KXH41454.1 - 5.6e-39 133.8 0.0 9.9e-39 133.0 0.0 1.4 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Glft2_N PF17994.1 KXH41454.1 - 0.13 12.2 1.1 0.41 10.6 0.2 2.0 2 0 0 2 2 2 0 Galactofuranosyltransferase 2 N-terminal Dabb PF07876.12 KXH41456.1 - 4.4e-14 52.9 0.0 5.3e-14 52.6 0.0 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain DUF4123 PF13503.6 KXH41456.1 - 0.062 13.7 0.0 0.07 13.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4123) FAA_hydrolase PF01557.18 KXH41457.1 - 3.4e-57 193.6 0.0 4.6e-57 193.2 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 KXH41457.1 - 4.6e-33 113.6 0.0 9.4e-33 112.6 0.0 1.5 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal HgmA PF04209.13 KXH41458.1 - 5.6e-199 661.2 0.0 6.4e-199 661.0 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase AA_permease_2 PF13520.6 KXH41459.1 - 9.2e-58 196.1 43.8 1.4e-57 195.5 43.6 1.3 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXH41459.1 - 1.1e-21 77.0 37.6 1.5e-21 76.5 37.6 1.1 1 0 0 1 1 1 1 Amino acid permease p450 PF00067.22 KXH41460.1 - 5.3e-66 223.3 0.0 6e-66 223.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.18 KXH41461.1 - 1.7e-15 56.8 0.1 3.1e-15 55.9 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH41461.1 - 2.4e-07 30.7 5.8 4.7e-07 29.8 5.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Syntaxin-6_N PF09177.11 KXH41461.1 - 0.1 13.1 0.1 0.27 11.8 0.1 1.6 1 0 0 1 1 1 0 Syntaxin 6, N-terminal SET PF00856.28 KXH41464.1 - 1.4e-13 51.5 0.3 6.6e-13 49.4 0.0 2.2 2 1 0 2 2 2 1 SET domain Polyketide_cyc2 PF10604.9 KXH41465.1 - 0.00031 21.0 0.0 0.00032 21.0 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport p450 PF00067.22 KXH41466.1 - 8.1e-53 179.8 0.0 1.2e-52 179.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 ADK PF00406.22 KXH41467.1 - 2e-24 86.4 0.0 2.5e-24 86.1 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KXH41467.1 - 7.9e-16 58.7 0.0 1.4e-15 57.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KXH41467.1 - 0.001 19.6 0.0 0.002 18.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 KXH41467.1 - 0.024 14.3 0.0 0.19 11.4 0.0 1.9 2 0 0 2 2 2 0 Thymidylate kinase Pkinase PF00069.25 KXH41470.1 - 2.2e-55 187.9 0.0 3.3e-55 187.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXH41470.1 - 1.7e-32 112.7 0.0 5.3e-31 107.9 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KXH41470.1 - 0.0041 16.1 0.0 0.006 15.6 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pox_ser-thr_kin PF05445.11 KXH41470.1 - 0.028 13.4 0.0 0.04 12.9 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.14 KXH41470.1 - 0.14 11.5 0.9 0.3 10.4 0.9 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HSP70 PF00012.20 KXH41472.1 - 5.2e-11 41.5 0.1 3.2e-10 38.9 0.0 1.8 2 0 0 2 2 2 1 Hsp70 protein FtsA PF14450.6 KXH41472.1 - 0.001 19.4 0.1 0.011 16.2 0.0 2.4 2 0 0 2 2 2 1 Cell division protein FtsA 3Beta_HSD PF01073.19 KXH41473.1 - 0.26 10.3 0.0 0.4 9.7 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family End3 PF12761.7 KXH41474.1 - 0.0027 17.9 5.5 0.0054 16.9 5.5 1.4 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 SPX PF03105.19 KXH41474.1 - 0.0042 17.1 14.2 0.0069 16.3 14.2 1.3 1 0 0 1 1 1 1 SPX domain Exo70 PF03081.15 KXH41474.1 - 0.023 13.8 0.0 0.047 12.7 0.0 1.5 1 0 0 1 1 1 0 Exo70 exocyst complex subunit TMF_DNA_bd PF12329.8 KXH41474.1 - 0.088 12.8 3.7 12 5.9 2.1 2.9 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF4201 PF13870.6 KXH41474.1 - 0.12 12.1 3.3 0.28 10.9 3.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) DUF2968 PF11180.8 KXH41474.1 - 0.19 11.4 4.7 0.51 9.9 4.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) Lebercilin PF15619.6 KXH41474.1 - 0.33 10.6 7.9 0.1 12.3 2.6 2.4 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Raftlin PF15250.6 KXH41474.1 - 5.6 5.6 7.6 1.9 7.1 5.0 1.4 1 1 0 1 1 1 0 Raftlin AKAP7_NLS PF10469.9 KXH41475.1 - 2.4e-33 115.8 0.0 2.9e-33 115.5 0.0 1.1 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain Hpt PF01627.23 KXH41476.1 - 2.5e-13 50.1 0.4 4e-13 49.4 0.4 1.4 1 1 0 1 1 1 1 Hpt domain NusB PF01029.18 KXH41476.1 - 0.033 14.4 0.3 0.14 12.4 0.0 1.8 2 0 0 2 2 2 0 NusB family Spore_III_AB PF09548.10 KXH41476.1 - 2.4 8.2 5.5 4.6 7.3 0.4 2.1 1 1 1 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) DUF3984 PF13136.6 KXH41477.1 - 7.4e-64 216.2 26.8 6.8e-63 213.1 26.8 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF3984) IKI3 PF04762.12 KXH41478.1 - 0 1018.9 0.0 0 1018.5 0.0 1.2 1 0 0 1 1 1 1 IKI3 family ANAPC4_WD40 PF12894.7 KXH41478.1 - 0.024 14.9 2.4 12 6.3 0.0 4.8 4 1 2 6 6 6 0 Anaphase-promoting complex subunit 4 WD40 domain Ras PF00071.22 KXH41480.1 - 1.1e-54 184.4 0.0 1.6e-54 183.9 0.0 1.2 1 0 0 1 1 1 1 Ras family IMS PF00817.20 KXH41480.1 - 4.5e-37 127.3 0.0 8.1e-37 126.5 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family Roc PF08477.13 KXH41480.1 - 1e-20 74.1 0.0 1.9e-20 73.3 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase IMS_C PF11799.8 KXH41480.1 - 7.1e-10 39.6 0.0 1.6e-09 38.5 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain Arf PF00025.21 KXH41480.1 - 9.3e-06 25.2 0.0 1.9e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KXH41480.1 - 0.015 14.8 0.0 0.028 13.9 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit SDA1 PF05285.12 KXH41481.1 - 1.1 8.6 6.6 1.2 8.4 6.6 1.1 1 0 0 1 1 1 0 SDA1 dsDNA_bind PF01984.20 KXH41482.1 - 0.17 12.1 4.3 0.34 11.2 4.3 1.4 1 0 0 1 1 1 0 Double-stranded DNA-binding domain Pyridoxal_deC PF00282.19 KXH41483.1 - 7.1e-14 51.3 0.0 1.1e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 KXH41483.1 - 7.3e-05 21.9 0.0 0.00024 20.2 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KXH41483.1 - 0.2 11.0 0.0 0.39 10.0 0.0 1.4 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Glyco_transf_34 PF05637.12 KXH41484.1 - 2.5e-73 246.7 0.0 3.1e-73 246.5 0.0 1.0 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family RINGv PF12906.7 KXH41485.1 - 1.5e-10 41.0 2.0 1.6e-09 37.7 0.4 2.2 2 0 0 2 2 2 1 RING-variant domain PHD_4 PF16866.5 KXH41485.1 - 0.0048 17.0 1.6 0.21 11.7 0.0 2.3 1 1 0 2 2 2 1 PHD-finger DUF5516 PF17637.2 KXH41485.1 - 0.044 13.5 0.7 0.11 12.3 0.2 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5516) zf-RING_2 PF13639.6 KXH41485.1 - 0.076 13.4 4.0 0.28 11.6 1.1 2.2 2 0 0 2 2 2 0 Ring finger domain PsbI PF02532.14 KXH41485.1 - 0.36 10.8 1.7 1 9.4 1.7 1.7 1 0 0 1 1 1 0 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) Proteasome PF00227.26 KXH41486.1 - 1.9e-51 174.3 0.0 3.4e-27 95.2 0.0 2.2 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.9 KXH41486.1 - 1.3e-10 40.8 0.3 3.2e-10 39.5 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Peptidase_S13 PF02113.15 KXH41486.1 - 0.22 10.2 0.4 1.1 7.9 0.1 1.9 2 0 0 2 2 2 0 D-Ala-D-Ala carboxypeptidase 3 (S13) family Ribonuclease_3 PF00636.26 KXH41487.1 - 7.2e-40 135.9 0.0 2.4e-20 73.1 0.0 2.6 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KXH41487.1 - 4.5e-22 78.6 0.0 5.4e-10 39.5 0.0 3.6 3 0 0 3 3 3 3 Ribonuclease-III-like Dicer_dimer PF03368.14 KXH41487.1 - 1.2e-21 76.7 0.0 4.7e-21 74.7 0.0 2.1 3 0 0 3 3 3 1 Dicer dimerisation domain DEAD PF00270.29 KXH41487.1 - 6.6e-19 68.3 0.0 1.4e-18 67.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXH41487.1 - 9.3e-18 64.6 0.1 3e-17 62.9 0.1 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXH41487.1 - 5.3e-15 55.8 0.0 1.1e-14 54.8 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD_2 PF06733.15 KXH41487.1 - 0.0089 15.7 0.0 0.021 14.5 0.0 1.5 1 0 0 1 1 1 1 DEAD_2 PRY PF13765.6 KXH41487.1 - 0.089 12.4 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 SPRY-associated domain SQHop_cyclase_C PF13243.6 KXH41491.1 - 0.015 14.4 0.0 0.022 13.8 0.0 1.2 1 0 0 1 1 1 0 Squalene-hopene cyclase C-terminal domain Rgp1 PF08737.10 KXH41492.1 - 7.7e-160 532.6 0.0 1.4e-159 531.8 0.0 1.4 1 0 0 1 1 1 1 Rgp1 Arrestin_C PF02752.22 KXH41492.1 - 0.00035 21.0 0.1 0.065 13.7 0.0 2.8 3 0 0 3 3 3 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 KXH41492.1 - 0.00052 20.1 0.0 0.0012 19.0 0.0 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain WD40 PF00400.32 KXH41493.1 - 8.4e-08 32.8 16.4 0.0018 19.1 0.2 7.1 8 0 0 8 8 8 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXH41493.1 - 0.00011 22.4 0.1 17 5.8 0.0 5.8 3 2 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain p450 PF00067.22 KXH41494.1 - 1e-65 222.3 0.0 1.4e-65 221.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ADH_N PF08240.12 KXH41495.1 - 4.8e-28 97.2 0.3 9.2e-28 96.3 0.3 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXH41495.1 - 1.1e-24 86.9 0.1 1.8e-24 86.2 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXH41495.1 - 0.00019 22.5 0.0 0.00029 21.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 KXH41495.1 - 0.043 13.3 0.3 0.092 12.2 0.3 1.6 1 0 0 1 1 1 0 short chain dehydrogenase 2-Hacid_dh_C PF02826.19 KXH41495.1 - 0.05 13.0 0.2 0.12 11.7 0.2 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Actin PF00022.19 KXH41496.1 - 1.3e-88 297.4 0.0 1.3e-52 178.8 0.0 2.0 1 1 1 2 2 2 2 Actin Asparaginase_2 PF01112.18 KXH41497.1 - 3.8e-46 157.5 2.8 5.3e-30 104.5 0.0 2.2 2 0 0 2 2 2 2 Asparaginase Tfb4 PF03850.14 KXH41498.1 - 2.2e-96 322.6 0.5 2.6e-96 322.4 0.5 1.0 1 0 0 1 1 1 1 Transcription factor Tfb4 UNC45-central PF11701.8 KXH41499.1 - 2.6e-56 189.9 0.1 1.8e-55 187.1 0.1 2.4 2 0 0 2 2 2 1 Myosin-binding striated muscle assembly central HEAT PF02985.22 KXH41499.1 - 0.0099 16.1 5.1 9.5 6.8 0.1 5.6 4 0 0 4 4 4 1 HEAT repeat DUF5631 PF18645.1 KXH41499.1 - 0.085 13.2 0.3 0.44 11.0 0.1 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5631) HEAT_2 PF13646.6 KXH41499.1 - 8.6 6.8 24.7 0.96 9.9 3.6 6.0 4 1 1 6 6 6 0 HEAT repeats tRNA_U5-meth_tr PF05958.11 KXH41500.1 - 1.7e-14 53.6 0.0 4.5e-13 48.9 0.0 2.4 2 1 0 2 2 2 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_15 PF09445.10 KXH41500.1 - 4.8e-07 29.5 0.0 8.9e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_25 PF13649.6 KXH41500.1 - 0.00016 22.3 0.0 0.0004 21.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH41500.1 - 0.00023 21.0 0.0 0.00052 19.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH41500.1 - 0.0065 17.1 0.0 0.019 15.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KXH41500.1 - 0.0089 15.4 0.0 0.017 14.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltrans_SAM PF10672.9 KXH41500.1 - 0.033 13.3 0.0 0.053 12.7 0.0 1.2 1 0 0 1 1 1 0 S-adenosylmethionine-dependent methyltransferase TRM PF02005.16 KXH41500.1 - 0.037 13.2 0.1 0.12 11.5 0.0 1.8 2 0 0 2 2 2 0 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_12 PF08242.12 KXH41500.1 - 0.056 14.2 0.0 0.18 12.6 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.15 KXH41500.1 - 0.08 12.6 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 MTS PF05175.14 KXH41500.1 - 0.1 12.1 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain G_glu_transpept PF01019.21 KXH41501.1 - 5.4e-165 550.0 0.0 6.2e-165 549.8 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase DUF2520 PF10728.9 KXH41501.1 - 0.13 12.0 0.0 4.7 7.0 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF2520) ALG11_N PF15924.5 KXH41502.1 - 1.4e-85 286.6 0.1 7.6e-85 284.2 0.0 2.0 2 0 0 2 2 2 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 KXH41502.1 - 3.4e-22 78.8 0.0 6.1e-22 78.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KXH41502.1 - 1.1e-11 45.3 0.0 2.4e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KXH41502.1 - 0.0029 17.6 0.0 0.0049 16.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 DAHP_synth_1 PF00793.20 KXH41502.1 - 0.063 12.1 0.0 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 DAHP synthetase I family 60KD_IMP PF02096.20 KXH41503.1 - 8.7e-05 22.5 0.1 0.00012 22.0 0.1 1.2 1 0 0 1 1 1 1 60Kd inner membrane protein Syntaxin_2 PF14523.6 KXH41504.1 - 3e-25 88.5 5.4 3e-25 88.5 5.4 2.5 2 1 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.19 KXH41504.1 - 2e-13 50.1 1.3 2e-13 50.1 1.3 2.2 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.25 KXH41504.1 - 0.00077 19.2 13.9 0.0033 17.1 13.9 2.0 1 1 0 1 1 1 1 Syntaxin Synaptobrevin PF00957.21 KXH41504.1 - 0.023 14.5 0.6 0.023 14.5 0.6 2.1 2 0 0 2 2 2 0 Synaptobrevin DUF883 PF05957.13 KXH41504.1 - 0.067 13.8 13.7 0.4 11.3 0.1 3.4 2 1 0 3 3 3 0 Bacterial protein of unknown function (DUF883) DUF1664 PF07889.12 KXH41504.1 - 0.088 12.9 11.7 3.9 7.5 0.6 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) MCPsignal PF00015.21 KXH41504.1 - 0.24 11.2 13.2 23 4.8 0.4 3.2 1 1 2 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Spectrin PF00435.21 KXH41504.1 - 0.31 11.5 12.3 1.7 9.1 2.2 3.2 2 1 1 3 3 3 0 Spectrin repeat Occludin_ELL PF07303.13 KXH41504.1 - 0.71 10.6 4.6 1.2 9.9 0.7 2.8 2 1 1 3 3 3 0 Occludin homology domain T2SSF PF00482.23 KXH41504.1 - 1.7 8.6 5.2 0.47 10.4 1.0 2.3 2 1 0 2 2 2 0 Type II secretion system (T2SS), protein F LPP PF04728.13 KXH41504.1 - 2.3 8.6 8.8 8.7 6.8 0.0 3.9 3 1 0 3 3 3 0 Lipoprotein leucine-zipper T3SSipB PF16535.5 KXH41504.1 - 6.2 7.3 13.1 1.4 9.4 5.5 2.6 3 0 0 3 3 3 0 Type III cell invasion protein SipB DUF16 PF01519.16 KXH41504.1 - 7.2 7.2 16.0 3 8.4 3.2 3.2 1 1 2 3 3 3 0 Protein of unknown function DUF16 Ndc1_Nup PF09531.10 KXH41505.1 - 2.1e-188 627.8 1.1 2.7e-188 627.5 1.1 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup NICE-3 PF07406.11 KXH41506.1 - 0.00038 20.5 2.7 0.016 15.2 0.0 2.5 3 0 0 3 3 3 2 NICE-3 protein DUF4129 PF13559.6 KXH41506.1 - 0.00099 19.3 1.1 0.0016 18.6 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4129) MASE3 PF17159.4 KXH41506.1 - 0.086 12.5 2.6 0.13 11.8 2.6 1.2 1 0 0 1 1 1 0 Membrane-associated sensor domain Na_Ca_ex PF01699.24 KXH41506.1 - 0.17 11.8 3.4 0.28 11.1 3.4 1.2 1 0 0 1 1 1 0 Sodium/calcium exchanger protein DUF3537 PF12056.8 KXH41506.1 - 1.4 7.7 3.5 2.1 7.1 3.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3537) Melibiase_2 PF16499.5 KXH41525.1 - 1.1e-25 90.4 2.8 2.1e-25 89.5 2.8 1.4 1 1 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 KXH41525.1 - 3.7e-09 36.5 0.0 6.1e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Alpha galactosidase C-terminal beta sandwich domain Glyco_hydro_88 PF07470.13 KXH41526.1 - 3.5e-13 49.3 0.2 4.9e-13 48.9 0.2 1.3 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Fungal_trans PF04082.18 KXH41527.1 - 2.1e-21 76.1 0.6 3.4e-21 75.5 0.1 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain MFS_1 PF07690.16 KXH41528.1 - 1.3e-21 77.0 30.0 1.9e-12 46.8 5.5 2.3 2 1 1 3 3 3 2 Major Facilitator Superfamily 2TM PF13239.6 KXH41528.1 - 0.038 14.3 0.1 0.038 14.3 0.1 4.4 4 1 1 5 5 5 0 2TM domain Tetraspanin PF00335.20 KXH41529.1 - 2.6e-05 24.1 5.9 3.7e-05 23.6 5.9 1.2 1 0 0 1 1 1 1 Tetraspanin family GerA PF03323.13 KXH41529.1 - 0.11 11.0 2.0 1.8 6.9 0.6 2.2 2 0 0 2 2 2 0 Bacillus/Clostridium GerA spore germination protein gag-asp_proteas PF13975.6 KXH41545.1 - 0.021 15.4 0.0 0.045 14.3 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease CDC45 PF02724.14 KXH41546.1 - 4.5 5.5 10.5 7.7 4.7 10.5 1.2 1 0 0 1 1 1 0 CDC45-like protein Ribosomal_S5 PF00333.20 KXH41547.1 - 9e-27 92.9 0.8 2.1e-26 91.7 0.8 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 KXH41547.1 - 9.4e-24 82.7 0.0 1.6e-23 81.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain FoP_duplication PF13865.6 KXH41547.1 - 2.6 8.6 14.3 6.8 7.3 14.3 1.6 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Rhodanese PF00581.20 KXH41548.1 - 4.6e-18 65.7 0.0 5.7e-10 39.7 0.0 2.3 2 0 0 2 2 2 2 Rhodanese-like domain zf-ANAPC11 PF12861.7 KXH41549.1 - 1e-45 153.7 10.8 1.2e-45 153.5 10.8 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 KXH41549.1 - 6e-22 77.7 12.4 8.2e-22 77.3 12.4 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KXH41549.1 - 6.3e-08 32.8 15.9 1.5e-06 28.4 15.9 2.4 1 1 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KXH41549.1 - 2.7e-05 24.1 11.0 0.0002 21.3 5.2 2.6 2 1 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KXH41549.1 - 8.9e-05 22.3 14.2 0.00038 20.3 14.2 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KXH41549.1 - 0.0008 19.2 12.7 0.017 15.0 12.7 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KXH41549.1 - 0.0019 17.8 11.4 0.016 14.8 11.4 2.1 1 1 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 KXH41549.1 - 0.0022 17.8 3.1 0.0022 17.8 3.1 2.4 1 1 1 2 2 2 1 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 KXH41549.1 - 0.0065 16.6 17.4 0.15 12.2 17.4 3.0 1 1 0 1 1 1 1 FANCL C-terminal domain zf-Nse PF11789.8 KXH41549.1 - 0.0069 16.2 4.5 0.013 15.3 4.5 1.5 1 1 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_2 PF13923.6 KXH41549.1 - 0.0069 16.2 13.7 0.0069 16.2 13.7 2.5 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KXH41549.1 - 0.0083 16.3 9.0 0.0083 16.3 9.0 2.3 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING Rad50_zn_hook PF04423.14 KXH41549.1 - 0.13 12.2 0.1 0.13 12.2 0.1 2.5 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-RING_11 PF17123.5 KXH41549.1 - 0.19 11.5 13.0 0.67 9.8 10.3 2.8 2 1 0 2 2 2 0 RING-like zinc finger zf-RING_5 PF14634.6 KXH41549.1 - 0.21 11.6 17.4 7.3 6.6 17.9 2.8 1 1 1 2 2 2 0 zinc-RING finger domain Prok-RING_4 PF14447.6 KXH41549.1 - 0.38 10.6 13.5 2.4 8.1 10.0 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-HIT PF04438.16 KXH41549.1 - 0.55 10.1 9.3 1.6 8.7 4.0 2.5 2 1 0 2 2 2 0 HIT zinc finger TerY_C PF15616.6 KXH41549.1 - 0.59 10.2 7.6 0.45 10.6 6.4 1.3 1 1 0 1 1 1 0 TerY-C metal binding domain zf-RING-like PF08746.11 KXH41549.1 - 2.1 8.7 13.2 16 5.9 13.2 2.2 1 1 0 1 1 1 0 RING-like domain UBZ_FAAP20 PF15750.5 KXH41549.1 - 2.2 8.3 8.5 2.7 8.0 0.8 2.8 2 1 1 3 3 3 0 Ubiquitin-binding zinc-finger RINGv PF12906.7 KXH41549.1 - 2.4 8.4 13.6 3.2 8.0 12.0 2.1 1 1 1 2 2 2 0 RING-variant domain DZR PF12773.7 KXH41549.1 - 3.9 7.6 12.9 4.5 7.4 5.9 2.2 1 1 1 2 2 2 0 Double zinc ribbon Opy2 PF09463.10 KXH41549.1 - 5.9 7.3 11.3 13 6.2 6.5 2.5 2 1 0 2 2 2 0 Opy2 protein ACTH_assoc PF16102.5 KXH41550.1 - 0.77 10.7 0.1 0.77 10.7 0.1 4.5 4 1 1 5 5 5 0 ACTH-associated domain FAD_binding_4 PF01565.23 KXH41551.1 - 9.2e-24 83.8 4.4 2.6e-23 82.3 3.3 2.1 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 KXH41551.1 - 0.007 16.4 0.2 0.019 15.1 0.1 1.8 2 0 0 2 2 2 1 Berberine and berberine like SnoaL_2 PF12680.7 KXH41552.1 - 0.097 13.3 0.1 0.13 12.9 0.1 1.2 1 0 0 1 1 1 0 SnoaL-like domain Syntaxin PF00804.25 KXH41553.1 - 3.8e-17 62.6 11.0 3.8e-17 62.6 11.0 2.1 1 1 0 2 2 2 1 Syntaxin SNARE PF05739.19 KXH41553.1 - 1.2e-08 34.8 2.9 1.7e-08 34.3 0.3 2.5 2 0 0 2 2 2 1 SNARE domain Chordopox_A33R PF05966.12 KXH41553.1 - 0.043 13.1 0.2 0.33 10.2 0.0 2.1 2 0 0 2 2 2 0 Chordopoxvirus A33R protein DUF2207 PF09972.9 KXH41553.1 - 0.13 11.0 0.0 0.18 10.6 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) V-SNARE PF05008.15 KXH41553.1 - 0.15 12.5 13.1 0.1 13.0 2.3 3.6 3 1 1 4 4 4 0 Vesicle transport v-SNARE protein N-terminus DUF515 PF04415.12 KXH41553.1 - 0.22 9.9 2.9 0.27 9.6 2.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF515) BLOC1_2 PF10046.9 KXH41553.1 - 0.28 11.5 7.8 3.9 7.8 2.2 3.4 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Allexi_40kDa PF05549.11 KXH41553.1 - 0.89 9.0 7.0 1.2 8.6 0.4 2.2 2 0 0 2 2 2 0 Allexivirus 40kDa protein TMCO5 PF14992.6 KXH41553.1 - 0.98 8.9 7.8 58 3.1 7.8 2.1 1 1 0 1 1 1 0 TMCO5 family ISG65-75 PF11727.8 KXH41553.1 - 1.2 8.3 7.2 0.78 8.9 0.0 2.3 2 0 0 2 2 2 0 Invariant surface glycoprotein DUF2229 PF09989.9 KXH41553.1 - 2 8.0 5.1 14 5.3 5.1 2.1 1 1 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) Gp-FAR-1 PF05823.12 KXH41553.1 - 2.2 8.6 5.3 37 4.6 2.2 2.6 1 1 2 3 3 3 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Laminin_II PF06009.12 KXH41553.1 - 5.5 7.0 10.6 6.4 6.8 3.3 2.4 2 1 0 2 2 2 0 Laminin Domain II Memo PF01875.17 KXH41554.1 - 9.3e-77 257.8 0.0 1.1e-76 257.6 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein PH_9 PF15410.6 KXH41592.1 - 4.7e-07 30.2 0.0 7.3e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 KXH41592.1 - 0.0048 17.4 0.1 0.0097 16.4 0.1 1.6 1 0 0 1 1 1 1 PH domain Imm53 PF15580.6 KXH41592.1 - 0.14 11.9 0.5 0.59 9.9 0.2 2.0 1 1 1 2 2 2 0 Immunity protein 53 Peptidase_C50 PF03568.17 KXH41594.1 - 3e-161 537.0 0.0 7.5e-161 535.7 0.0 1.7 1 0 0 1 1 1 1 Peptidase family C50 TPR_12 PF13424.6 KXH41594.1 - 7.5e-06 26.1 30.7 0.011 16.0 3.6 6.8 7 0 0 7 7 7 3 Tetratricopeptide repeat CHAT PF12770.7 KXH41594.1 - 2.3e-05 24.0 0.0 0.01 15.3 0.0 3.7 3 0 0 3 3 3 1 CHAT domain TPR_19 PF14559.6 KXH41594.1 - 0.02 15.4 14.5 3.9 8.1 0.0 5.9 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 KXH41594.1 - 0.025 15.2 7.0 0.088 13.5 4.7 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 KXH41594.1 - 0.032 14.3 1.5 2.1 8.6 0.1 3.6 2 0 0 2 2 2 0 Tetratricopeptide repeat ROS_MUCR PF05443.11 KXH41594.1 - 0.056 13.5 0.1 6.5 6.8 0.0 4.1 4 0 0 4 4 4 0 ROS/MUCR transcriptional regulator protein ANAPC3 PF12895.7 KXH41594.1 - 1.2 9.5 12.8 0.22 11.8 0.1 4.5 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 KXH41594.1 - 2.2 8.6 22.4 3.3 8.0 0.2 6.9 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_4 PF07721.14 KXH41594.1 - 4.2 8.3 8.2 25 5.9 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF5321 PF17254.2 KXH41595.1 - 1.1e-61 206.9 2.1 1.4e-61 206.6 2.1 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5321) SIR2 PF02146.17 KXH41596.1 - 1.6e-31 109.6 0.0 2.3e-31 109.1 0.0 1.2 1 0 0 1 1 1 1 Sir2 family Cation_efflux PF01545.21 KXH41597.1 - 1.7e-48 165.0 7.0 2.3e-48 164.6 7.0 1.2 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KXH41597.1 - 2.9e-05 24.1 0.6 7.3e-05 22.8 0.1 1.9 2 0 0 2 2 2 1 Dimerisation domain of Zinc Transporter FGGY_N PF00370.21 KXH41598.1 - 1.2e-08 34.9 0.0 4.5e-07 29.7 0.0 2.2 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain SRP-alpha_N PF04086.13 KXH41598.1 - 0.036 14.0 0.0 0.06 13.3 0.0 1.4 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal ComK PF06338.11 KXH41598.1 - 0.072 12.7 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 ComK protein Mito_fiss_reg PF05308.11 KXH41613.1 - 0.42 10.6 4.8 0.46 10.5 4.8 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator PRIMA1 PF16101.5 KXH41613.1 - 4.7 7.3 9.8 5.6 7.0 9.8 1.3 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 CAP_N PF01213.19 KXH41613.1 - 6 6.2 10.1 6.9 6.1 10.1 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF3915 PF13054.6 KXH41614.1 - 0.93 9.5 6.2 1 9.3 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3915) zf-C3HC4_3 PF13920.6 KXH41614.1 - 3.9 7.4 8.8 4.4 7.2 4.0 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Aldo_ket_red PF00248.21 KXH41615.1 - 6.5e-55 186.4 0.0 8.2e-55 186.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family CDH-cyt PF16010.5 KXH41616.1 - 1.9e-22 79.8 1.0 4.3e-22 78.7 0.1 2.1 2 1 0 2 2 2 1 Cytochrome domain of cellobiose dehydrogenase SGL PF08450.12 KXH41616.1 - 0.00063 19.4 0.1 0.0097 15.5 0.1 2.6 2 1 1 3 3 3 1 SMP-30/Gluconolactonase/LRE-like region PD40 PF07676.12 KXH41616.1 - 0.0011 18.8 0.1 0.0044 16.9 0.1 2.1 1 0 0 1 1 1 1 WD40-like Beta Propeller Repeat Arylesterase PF01731.20 KXH41616.1 - 0.0045 17.2 0.0 0.083 13.1 0.0 2.9 4 0 0 4 4 4 1 Arylesterase Sugar_tr PF00083.24 KXH41617.1 - 2.7e-70 237.5 13.3 6.8e-61 206.5 7.4 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KXH41617.1 - 4.7e-22 78.4 34.6 9.8e-21 74.1 21.9 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily zf-C2H2_4 PF13894.6 KXH41618.1 - 0.0043 17.8 3.6 0.013 16.3 0.2 2.9 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2 PF00096.26 KXH41618.1 - 0.0063 16.9 3.4 0.013 15.9 0.7 2.8 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-met PF12874.7 KXH41618.1 - 0.094 13.1 0.0 0.23 11.9 0.0 1.7 1 0 0 1 1 1 0 Zinc-finger of C2H2 type RhgB_N PF09284.10 KXH41619.1 - 5e-108 360.4 5.1 7.4e-108 359.8 5.1 1.3 1 0 0 1 1 1 1 Rhamnogalacturonan lyase B, N-terminal CBM-like PF14683.6 KXH41619.1 - 4.3e-44 150.3 0.0 1.3e-43 148.7 0.0 1.9 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.6 KXH41619.1 - 3e-24 84.6 6.5 1.1e-23 82.8 6.5 2.1 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.6 KXH41619.1 - 0.00054 20.2 6.1 0.00054 20.2 6.1 3.9 4 1 0 4 4 4 1 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 KXH41619.1 - 0.014 15.4 2.5 0.037 14.0 1.0 2.5 3 1 0 3 3 3 0 CarboxypepD_reg-like domain DUF1735 PF08522.10 KXH41619.1 - 1.3 9.6 8.4 12 6.5 0.1 3.7 5 2 0 5 5 5 0 Domain of unknown function (DUF1735) FAD_binding_3 PF01494.19 KXH41622.1 - 4.9e-18 65.5 0.0 6.5e-18 65.1 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KXH41622.1 - 7.6e-08 32.3 0.2 0.0061 16.2 0.0 2.5 2 1 1 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXH41622.1 - 1.2e-06 28.0 0.2 0.024 13.9 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXH41622.1 - 3.4e-06 27.5 0.1 0.0019 18.7 0.0 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXH41622.1 - 0.00061 20.0 0.1 0.0016 18.6 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain ApbA PF02558.16 KXH41622.1 - 0.12 12.0 0.2 0.22 11.2 0.2 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA GrpB PF04229.14 KXH41623.1 - 2.5e-48 164.3 0.0 3e-48 164.0 0.0 1.1 1 0 0 1 1 1 1 GrpB protein GCIP PF13324.6 KXH41624.1 - 1.1e-23 84.1 0.0 4e-23 82.3 0.0 1.8 2 1 0 2 2 2 1 Grap2 and cyclin-D-interacting Nop14 PF04147.12 KXH41624.1 - 0.033 12.4 1.8 0.045 12.0 1.8 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 KXH41624.1 - 0.069 11.4 3.2 0.097 11.0 3.2 1.2 1 0 0 1 1 1 0 CDC45-like protein CNDH2_C PF16858.5 KXH41624.1 - 0.07 13.0 1.5 0.11 12.3 1.5 1.2 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term DUF4611 PF15387.6 KXH41624.1 - 0.35 11.1 8.0 0.79 10.0 8.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Pox_Ag35 PF03286.14 KXH41624.1 - 0.53 10.0 5.8 5.9 6.6 5.8 2.4 2 0 0 2 2 2 0 Pox virus Ag35 surface protein RRN3 PF05327.11 KXH41624.1 - 0.57 8.6 5.4 0.94 7.9 5.4 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 TisB_toxin PF13939.6 KXH41624.1 - 0.76 9.6 2.1 1.6 8.6 2.1 1.5 1 0 0 1 1 1 0 Toxin TisB, type I toxin-antitoxin system TFB6 PF17110.5 KXH41624.1 - 0.86 9.3 7.7 1.9 8.2 4.7 2.6 3 0 0 3 3 3 0 Subunit 11 of the general transcription factor TFIIH DUF2457 PF10446.9 KXH41624.1 - 1.1 8.3 15.9 1.7 7.7 15.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CENP-B_dimeris PF09026.10 KXH41624.1 - 2 8.8 17.1 6.8 7.2 16.6 2.0 2 0 0 2 2 2 0 Centromere protein B dimerisation domain FAM176 PF14851.6 KXH41624.1 - 2.2 7.9 4.3 5.2 6.7 4.3 1.6 1 0 0 1 1 1 0 FAM176 family DNA_pol_phi PF04931.13 KXH41624.1 - 2.5 6.1 14.0 0.38 8.8 10.4 1.4 2 0 0 2 2 2 0 DNA polymerase phi Dicty_REP PF05086.12 KXH41624.1 - 5.9 4.7 4.8 9.4 4.1 4.8 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Nro1 PF12753.7 KXH41624.1 - 7.8 5.3 7.7 13 4.6 7.7 1.2 1 0 0 1 1 1 0 Nuclear pore complex subunit Nro1 PRKCSH-like PF12999.7 KXH41625.1 - 6.8e-43 146.5 4.6 2.4e-23 82.8 0.5 2.7 3 0 0 3 3 2 2 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 KXH41625.1 - 8.4e-31 106.7 4.9 5e-30 104.2 0.7 2.6 3 0 0 3 3 3 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 KXH41625.1 - 5.5e-11 43.3 2.3 8.4e-11 42.7 0.8 2.2 2 0 0 2 2 1 1 Glucosidase II beta subunit-like protein ATG27 PF09451.10 KXH41625.1 - 0.0011 18.9 0.3 0.002 18.1 0.3 1.4 1 0 0 1 1 1 1 Autophagy-related protein 27 NPV_P10 PF05531.12 KXH41625.1 - 0.0036 17.7 2.4 1.3 9.5 0.1 2.6 3 0 0 3 3 2 1 Nucleopolyhedrovirus P10 protein Snapin_Pallidin PF14712.6 KXH41625.1 - 0.0045 17.4 1.6 0.095 13.1 0.1 2.5 2 0 0 2 2 2 1 Snapin/Pallidin Mod_r PF07200.13 KXH41625.1 - 0.072 13.2 7.8 0.12 12.4 0.3 2.9 2 1 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein HIP1_clath_bdg PF16515.5 KXH41625.1 - 0.18 12.4 10.9 0.037 14.6 3.6 2.7 2 1 1 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 UPF0242 PF06785.11 KXH41625.1 - 0.18 11.9 8.7 0.14 12.2 5.2 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus SKA2 PF16740.5 KXH41625.1 - 0.39 10.5 7.6 13 5.7 0.1 3.7 3 1 1 4 4 4 0 Spindle and kinetochore-associated protein 2 DUF1664 PF07889.12 KXH41625.1 - 0.4 10.7 7.6 1.9 8.5 1.4 2.5 3 0 0 3 3 2 0 Protein of unknown function (DUF1664) Spc7 PF08317.11 KXH41625.1 - 0.49 9.2 14.9 2.9 6.7 9.0 2.6 2 1 0 2 2 2 0 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 KXH41625.1 - 0.56 10.3 19.0 4.7 7.3 7.0 3.2 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein DUF4200 PF13863.6 KXH41625.1 - 0.73 10.3 20.4 3.2 8.2 9.7 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4200) APG6_N PF17675.1 KXH41625.1 - 0.88 10.1 14.3 6.7 7.3 4.6 3.3 3 0 0 3 3 3 0 Apg6 coiled-coil region Sec34 PF04136.15 KXH41625.1 - 0.93 9.4 4.7 31 4.4 0.0 3.0 3 0 0 3 3 3 0 Sec34-like family IATP PF04568.12 KXH41625.1 - 1.2 9.6 10.2 5.7 7.4 5.2 2.6 2 0 0 2 2 2 0 Mitochondrial ATPase inhibitor, IATP AAA_lid_9 PF17871.1 KXH41625.1 - 1.3 9.0 6.3 30 4.6 0.0 3.1 3 0 0 3 3 3 0 AAA lid domain DUF3086 PF11285.8 KXH41625.1 - 2.1 7.4 5.7 1.8 7.6 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3086) Jnk-SapK_ap_N PF09744.9 KXH41625.1 - 2.4 8.4 19.2 19 5.5 8.0 3.2 2 1 0 3 3 3 0 JNK_SAPK-associated protein-1 Phage_GP20 PF06810.11 KXH41625.1 - 2.8 7.7 15.1 0.66 9.8 0.2 3.3 2 1 1 3 3 3 0 Phage minor structural protein GP20 Ax_dynein_light PF10211.9 KXH41625.1 - 2.9 7.8 14.7 0.25 11.3 4.4 2.9 3 0 0 3 3 3 0 Axonemal dynein light chain DUF4407 PF14362.6 KXH41625.1 - 3 7.1 8.8 0.7 9.2 4.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) OmpH PF03938.14 KXH41625.1 - 3.1 8.1 12.8 11 6.4 5.3 2.9 2 1 0 3 3 3 0 Outer membrane protein (OmpH-like) ZapB PF06005.12 KXH41625.1 - 3.8 8.0 15.7 6 7.4 0.6 3.5 3 1 0 3 3 3 0 Cell division protein ZapB ABC_tran_CTD PF16326.5 KXH41625.1 - 3.9 7.8 10.2 0.53 10.6 1.7 3.3 4 0 0 4 4 3 0 ABC transporter C-terminal domain BLOC1_2 PF10046.9 KXH41625.1 - 4 7.8 7.9 3.9 7.8 0.8 2.8 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1465 PF07323.12 KXH41625.1 - 5.1 6.9 7.0 3.6 7.4 0.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1465) Prefoldin_2 PF01920.20 KXH41625.1 - 5.2 7.1 16.2 6.1 6.9 3.7 3.6 3 1 0 3 3 3 0 Prefoldin subunit Spc29 PF17082.5 KXH41625.1 - 5.8 6.7 7.5 25 4.6 7.5 1.9 1 1 0 1 1 1 0 Spindle Pole Component 29 FAM184 PF15665.5 KXH41625.1 - 6.1 6.6 15.4 4.5 7.0 10.2 2.4 2 1 0 2 2 2 0 Family with sequence similarity 184, A and B GTP-bdg_M PF16360.5 KXH41625.1 - 6.4 7.5 11.3 0.27 11.8 3.4 2.8 3 1 1 4 4 3 0 GTP-binding GTPase Middle Region Fib_alpha PF08702.10 KXH41625.1 - 7.3 6.8 7.0 4.4 7.5 2.6 2.5 2 1 2 4 4 3 0 Fibrinogen alpha/beta chain family Filament PF00038.21 KXH41625.1 - 7.6 6.0 18.1 11 5.5 0.5 3.0 2 1 0 3 3 3 0 Intermediate filament protein Rtf2 PF04641.12 KXH41626.1 - 7.4e-52 176.3 0.6 9.2e-52 176.0 0.6 1.1 1 0 0 1 1 1 1 Rtf2 RING-finger Prok-RING_4 PF14447.6 KXH41626.1 - 9.6e-05 22.2 0.5 0.00024 20.9 0.5 1.6 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KXH41626.1 - 0.00042 20.3 0.2 0.0027 17.7 0.0 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 KXH41626.1 - 0.0025 18.1 0.1 0.0058 16.9 0.1 1.6 1 1 1 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 KXH41626.1 - 0.0088 16.0 0.1 0.015 15.3 0.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-Nse PF11789.8 KXH41626.1 - 0.011 15.6 0.1 0.043 13.6 0.3 1.9 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_2 PF13923.6 KXH41626.1 - 0.011 15.5 0.3 0.02 14.7 0.3 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KXH41626.1 - 0.028 14.2 0.8 0.23 11.3 0.0 2.3 2 0 0 2 2 2 0 RING-like zinc finger Zn-ribbon_8 PF09723.10 KXH41626.1 - 0.066 13.3 1.2 0.16 12.2 1.2 1.5 1 0 0 1 1 1 0 Zinc ribbon domain zf-C3HC4_3 PF13920.6 KXH41626.1 - 0.15 11.9 0.1 0.29 11.0 0.1 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXH41626.1 - 0.17 11.8 0.3 0.31 11.0 0.3 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FAT PF02259.23 KXH41627.1 - 5e-132 440.3 8.2 1.2e-131 439.0 8.2 1.7 1 0 0 1 1 1 1 FAT domain DUF3385 PF11865.8 KXH41627.1 - 1.4e-77 259.1 1.2 2e-71 239.1 0.2 5.2 4 1 0 4 4 4 2 Domain of unknown function (DUF3385) PI3_PI4_kinase PF00454.27 KXH41627.1 - 9.4e-74 248.4 0.1 1.9e-73 247.4 0.1 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FRB_dom PF08771.11 KXH41627.1 - 1.8e-45 153.4 0.3 1.8e-45 153.4 0.3 3.6 4 0 0 4 4 3 1 FKBP12-rapamycin binding domain HEAT PF02985.22 KXH41627.1 - 3.8e-15 54.7 23.2 0.00042 20.3 0.0 12.0 12 0 0 12 12 12 3 HEAT repeat HEAT_2 PF13646.6 KXH41627.1 - 4.7e-15 55.8 14.5 0.00019 21.8 0.0 8.8 7 1 1 9 9 9 2 HEAT repeats FATC PF02260.20 KXH41627.1 - 2.1e-13 49.8 0.1 6.6e-13 48.2 0.1 1.9 1 0 0 1 1 1 1 FATC domain HEAT_EZ PF13513.6 KXH41627.1 - 7.6e-11 42.3 18.4 0.0047 17.4 0.2 11.4 9 3 3 12 12 11 2 HEAT-like repeat IFRD PF05004.13 KXH41627.1 - 1.3e-07 31.0 4.5 0.0019 17.4 0.9 4.5 3 1 0 4 4 4 2 Interferon-related developmental regulator (IFRD) Vac14_Fab1_bd PF12755.7 KXH41627.1 - 8.1e-06 26.4 0.6 1.3e+02 3.2 0.0 7.7 7 3 1 8 8 7 0 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 KXH41627.1 - 0.00017 21.2 3.4 13 5.3 0.0 5.9 5 1 1 6 6 6 0 CLASP N terminal Baculo_PEP_C PF04513.12 KXH41627.1 - 0.00025 21.1 0.9 0.0028 17.7 0.1 3.2 2 0 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus Adaptin_N PF01602.20 KXH41627.1 - 0.00068 18.3 11.3 0.015 13.9 0.1 4.2 4 0 0 4 4 4 2 Adaptin N terminal region Cnd1 PF12717.7 KXH41627.1 - 0.00076 19.6 6.8 0.014 15.4 0.0 5.7 4 2 2 7 7 7 2 non-SMC mitotic condensation complex subunit 1 Sec7_N PF12783.7 KXH41627.1 - 0.036 14.0 5.8 6.2 6.7 0.0 4.9 4 1 0 4 4 4 0 Guanine nucleotide exchange factor in Golgi transport N-terminal V-ATPase_H_N PF03224.14 KXH41627.1 - 0.047 13.0 1.2 27 3.9 0.0 3.8 3 1 0 4 4 4 0 V-ATPase subunit H VirDNA-topo-I_N PF09266.10 KXH41627.1 - 0.09 12.9 0.1 0.26 11.5 0.1 1.8 1 0 0 1 1 1 0 Viral DNA topoisomerase I, N-terminal Beta-lactamase PF00144.24 KXH41628.1 - 9.7e-38 130.2 0.2 1.4e-37 129.6 0.2 1.1 1 0 0 1 1 1 1 Beta-lactamase Fungal_trans_2 PF11951.8 KXH41629.1 - 1.2e-08 34.2 0.1 3.1e-08 32.8 0.1 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Chlam_OMP3 PF03503.13 KXH41629.1 - 0.016 15.5 0.8 0.032 14.5 0.8 1.5 1 0 0 1 1 1 0 Chlamydia cysteine-rich outer membrane protein 3 CVNH PF08881.10 KXH41630.1 - 6.9e-11 42.7 0.0 1e-10 42.2 0.0 1.3 1 0 0 1 1 1 1 CVNH domain C1_1 PF00130.22 KXH41630.1 - 0.015 15.1 0.4 0.044 13.7 0.4 1.8 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DAO PF01266.24 KXH41631.1 - 5.2e-19 69.0 1.7 1e-14 54.9 0.2 2.4 2 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KXH41631.1 - 4.8e-05 23.4 0.0 8.3e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KXH41631.1 - 0.00017 21.7 0.1 0.00066 19.9 0.1 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KXH41631.1 - 0.0014 17.9 0.0 0.0024 17.2 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 KXH41631.1 - 0.013 14.7 0.0 0.018 14.3 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXH41631.1 - 0.047 12.8 0.0 0.065 12.4 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.12 KXH41631.1 - 0.084 11.9 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Sugar_tr PF00083.24 KXH41633.1 - 2.6e-73 247.4 22.2 3.1e-73 247.2 22.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH41633.1 - 4.2e-16 58.8 24.8 1.9e-15 56.7 23.4 2.3 2 1 1 3 3 3 1 Major Facilitator Superfamily MFS_2 PF13347.6 KXH41633.1 - 1e-08 34.2 14.7 0.00015 20.5 4.1 2.5 2 1 0 2 2 2 2 MFS/sugar transport protein DUF3176 PF11374.8 KXH41635.1 - 5.2e-36 123.1 2.0 1.4e-35 121.7 2.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) Neurensin PF14927.6 KXH41635.1 - 0.057 13.1 0.6 0.14 11.9 0.6 1.8 1 1 0 1 1 1 0 Neurensin Tyrosinase PF00264.20 KXH41636.1 - 1.4e-34 120.4 3.5 5.1e-34 118.5 3.5 1.8 1 1 0 1 1 1 1 Common central domain of tyrosinase Dehydratase_hem PF13816.6 KXH41637.1 - 1.2e-103 346.8 0.1 1.4e-103 346.6 0.1 1.0 1 0 0 1 1 1 1 Haem-containing dehydratase DUF4188 PF13826.6 KXH41637.1 - 5.9e-07 29.8 0.0 0.046 14.1 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4188) PI-PLC-C1 PF16670.5 KXH41637.1 - 0.094 11.8 0.0 0.22 10.6 0.0 1.5 2 0 0 2 2 2 0 Phosphoinositide phospholipase C, Ca2+-dependent DUF2524 PF10732.9 KXH41638.1 - 0.32 11.3 5.3 0.84 10.0 0.3 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF2524) Lactamase_B PF00753.27 KXH41639.1 - 9.3e-11 42.1 1.6 1.5e-10 41.4 1.6 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KXH41639.1 - 4.7e-07 29.5 0.6 8e-07 28.8 0.5 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Methyltransf_23 PF13489.6 KXH41640.1 - 2.5e-14 53.5 0.0 3.7e-14 52.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KXH41640.1 - 8.2e-14 51.5 0.0 1.1e-13 51.1 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 KXH41640.1 - 1.6e-13 51.1 0.0 6.7e-13 49.2 0.0 2.0 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH41640.1 - 1.2e-10 41.4 0.0 1.9e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH41640.1 - 1.5e-10 41.6 0.0 5.1e-10 39.9 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH41640.1 - 2.3e-08 34.7 0.1 1.4e-07 32.1 0.0 2.2 3 0 0 3 3 3 1 Methyltransferase domain PCMT PF01135.19 KXH41640.1 - 0.00013 21.7 0.0 0.00024 21.0 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) zf-C2H2 PF00096.26 KXH41654.1 - 0.0017 18.7 0.5 0.0017 18.7 0.5 3.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type DUF3664 PF12406.8 KXH41654.1 - 0.27 11.9 2.7 0.49 11.0 1.6 2.0 2 0 0 2 2 2 0 Surface protein IBR PF01485.21 KXH41654.1 - 5.5 7.3 11.0 7.8 6.8 0.1 2.8 3 0 0 3 3 3 0 IBR domain, a half RING-finger domain Ank PF00023.30 KXH41656.1 - 2.9e-26 90.7 0.8 9.7e-05 22.6 0.1 8.0 8 0 0 8 8 7 4 Ankyrin repeat Ank_2 PF12796.7 KXH41656.1 - 5.6e-26 91.0 0.1 4.4e-08 33.6 0.0 5.8 5 1 1 6 6 6 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXH41656.1 - 3.3e-20 70.0 1.4 0.00041 20.6 0.0 8.4 8 0 0 8 8 8 4 Ankyrin repeat Ank_4 PF13637.6 KXH41656.1 - 4e-20 71.9 0.1 0.0046 17.5 0.0 6.5 5 1 2 7 7 6 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXH41656.1 - 2.5e-14 53.1 1.4 5.9e-06 26.4 0.0 5.1 6 0 0 6 6 6 2 Ankyrin repeats (many copies) Torus PF16131.5 KXH41656.1 - 1.7e-12 48.0 3.7 1e-05 26.2 0.4 2.8 1 1 1 2 2 2 2 Torus domain zf_CCCH_4 PF18345.1 KXH41656.1 - 1.9e-08 34.1 18.7 0.00025 21.0 5.7 2.7 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 KXH41656.1 - 3.2e-08 33.2 13.3 0.0004 20.1 2.2 2.6 2 0 0 2 2 2 2 CCCH-type zinc finger zf-CCCH PF00642.24 KXH41656.1 - 1.9e-06 27.6 13.7 0.0059 16.5 3.9 2.6 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 KXH41656.1 - 0.021 15.3 17.2 0.13 12.8 5.6 2.9 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 KXH41656.1 - 0.32 11.2 7.0 7.5 6.8 0.5 3.3 4 0 0 4 4 3 0 Zinc-finger containing family LysM PF01476.20 KXH41657.1 - 9.3e-21 73.6 0.9 6.5e-10 38.9 0.3 2.1 2 0 0 2 2 2 2 LysM domain F-box_4 PF15966.5 KXH41658.1 - 0.0071 16.2 0.0 0.021 14.7 0.0 1.8 1 0 0 1 1 1 1 F-box F-box-like PF12937.7 KXH41658.1 - 0.21 11.5 0.1 0.21 11.5 0.1 2.9 3 0 0 3 3 3 0 F-box-like Inhibitor_I9 PF05922.16 KXH41659.1 - 1.4e-17 64.1 0.1 2.6e-17 63.3 0.1 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 Peptidase_S8 PF00082.22 KXH41659.1 - 2.2e-09 37.0 12.7 1.4e-05 24.6 2.2 2.3 1 1 1 2 2 2 2 Subtilase family Pyr_redox_2 PF07992.14 KXH41661.1 - 1.4e-37 129.5 0.0 1.7e-37 129.3 0.0 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXH41661.1 - 8.3e-08 32.7 0.1 2.5e-07 31.1 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXH41661.1 - 0.12 11.6 1.3 3.9 6.6 1.0 2.2 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXH41661.1 - 0.16 12.2 0.0 47 4.3 0.0 3.3 4 0 0 4 4 4 0 NAD(P)-binding Rossmann-like domain Fungal_trans_2 PF11951.8 KXH41662.1 - 5.2e-28 97.9 6.2 9.7e-28 97.0 6.2 1.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.25 KXH41663.1 - 1.1e-26 93.6 0.0 1.4e-26 93.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXH41663.1 - 6.5e-17 61.9 0.0 7.6e-17 61.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KXH41663.1 - 0.00027 20.5 0.0 0.0027 17.2 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KXH41663.1 - 0.041 13.8 0.0 0.065 13.1 0.0 1.3 1 0 0 1 1 1 0 KR domain Lactococcin PF04369.13 KXH41663.1 - 0.068 13.3 0.1 0.88 9.7 0.0 2.2 2 0 0 2 2 2 0 Lactococcin-like family Aa_trans PF01490.18 KXH41664.1 - 2e-39 135.4 32.6 2.3e-39 135.3 32.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Herpes_teg_N PF04843.12 KXH41664.1 - 0.019 14.6 0.1 0.076 12.7 0.0 1.8 2 0 0 2 2 2 0 Herpesvirus tegument protein, N-terminal conserved region HsbA PF12296.8 KXH41665.1 - 7.8e-16 58.6 1.6 7.8e-16 58.6 1.6 2.2 2 0 0 2 2 2 1 Hydrophobic surface binding protein A MFMR_assoc PF16596.5 KXH41665.1 - 0.67 10.4 11.2 1.5 9.3 11.2 1.5 1 0 0 1 1 1 0 Disordered region downstream of MFMR Med3 PF11593.8 KXH41665.1 - 5.2 6.2 12.5 8.4 5.5 12.5 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal peroxidase PF00141.23 KXH41667.1 - 4.2e-30 105.1 0.2 5.7e-30 104.7 0.2 1.2 1 0 0 1 1 1 1 Peroxidase Peroxidase_ext PF11895.8 KXH41667.1 - 1.1e-05 25.3 0.0 2.5e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Fungal peroxidase extension region Aldo_ket_red PF00248.21 KXH41668.1 - 0.021 14.0 0.0 0.031 13.5 0.0 1.4 1 1 0 1 1 1 0 Aldo/keto reductase family HeLo PF14479.6 KXH41669.1 - 7e-06 26.0 0.5 2.5e-05 24.2 0.1 2.0 2 0 0 2 2 2 1 Prion-inhibition and propagation Ank_5 PF13857.6 KXH41670.1 - 6.4e-31 106.0 1.9 9.6e-07 29.0 0.2 6.9 6 0 0 6 6 6 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXH41670.1 - 6.1e-29 100.4 0.1 1.8e-09 38.1 0.0 6.1 2 2 3 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXH41670.1 - 1.4e-24 86.1 4.4 3.8e-06 27.3 0.1 7.3 5 2 2 7 7 7 4 Ankyrin repeats (many copies) Pkinase PF00069.25 KXH41670.1 - 2.4e-23 82.9 0.0 6.3e-23 81.5 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Ank_3 PF13606.6 KXH41670.1 - 1.8e-22 76.9 4.6 0.028 15.0 0.0 9.3 8 0 0 8 8 8 5 Ankyrin repeat Pkinase_Tyr PF07714.17 KXH41670.1 - 1.3e-20 73.8 0.0 2.4e-20 72.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Ank PF00023.30 KXH41670.1 - 6e-16 58.1 14.5 0.081 13.4 0.2 8.7 9 0 0 9 9 9 5 Ankyrin repeat APH PF01636.23 KXH41670.1 - 0.022 14.7 0.1 3.8 7.4 0.0 2.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXH41670.1 - 0.049 12.4 0.0 0.089 11.5 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 KXH41670.1 - 0.12 11.7 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Fungal_trans_2 PF11951.8 KXH41671.1 - 0.00015 20.7 0.0 0.00027 19.9 0.0 1.4 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH41671.1 - 0.0098 16.0 1.9 0.015 15.4 1.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Oxidored_FMN PF00724.20 KXH41682.1 - 6e-14 52.1 0.0 7.1e-14 51.8 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF1100 PF06500.11 KXH41683.1 - 1.6e-07 30.5 0.0 2.2e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Abhydrolase_6 PF12697.7 KXH41683.1 - 1.9e-05 25.4 3.5 3.1e-05 24.7 3.5 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 KXH41683.1 - 2.8e-05 23.9 0.3 8e-05 22.4 0.1 1.7 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 KXH41683.1 - 6.5e-05 22.5 0.0 0.00014 21.4 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family AXE1 PF05448.12 KXH41683.1 - 0.006 15.3 0.0 0.79 8.3 0.0 2.2 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) BAAT_C PF08840.11 KXH41683.1 - 0.011 15.6 0.0 0.022 14.7 0.0 1.4 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_1 PF00561.20 KXH41683.1 - 0.012 15.3 0.1 0.028 14.1 0.1 1.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold DLH PF01738.18 KXH41683.1 - 0.023 14.2 0.0 0.31 10.5 0.0 2.5 2 1 0 2 2 2 0 Dienelactone hydrolase family SPC25 PF06703.11 KXH41684.1 - 0.05 13.4 3.5 0.65 9.8 0.1 2.3 1 1 1 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Zn_clus PF00172.18 KXH41685.1 - 1.5e-06 28.2 9.8 2.9e-06 27.3 9.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KXH41685.1 - 0.0057 15.5 0.0 0.0093 14.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DNA_pol_A_exo1 PF01612.20 KXH41686.1 - 9.5e-13 48.2 0.0 5.9e-12 45.6 0.0 2.0 1 1 0 1 1 1 1 3'-5' exonuclease MFS_1 PF07690.16 KXH41687.1 - 1.7e-20 73.3 27.5 4.1e-19 68.7 14.3 3.0 1 1 2 3 3 3 2 Major Facilitator Superfamily FPN1 PF06963.12 KXH41687.1 - 0.0053 15.4 0.8 0.0053 15.4 0.8 1.8 2 0 0 2 2 2 1 Ferroportin1 (FPN1) Adeno_PIX PF03955.14 KXH41687.1 - 0.63 10.2 4.7 1.9 8.7 0.1 2.5 3 0 0 3 3 3 0 Adenovirus hexon-associated protein (IX) Mntp PF02659.15 KXH41687.1 - 1.2 8.8 6.2 4 7.2 0.5 3.0 3 1 0 3 3 3 0 Putative manganese efflux pump LapA_dom PF06305.11 KXH41687.1 - 2.3 8.1 5.1 1.3 8.9 0.0 3.0 2 1 1 3 3 3 0 Lipopolysaccharide assembly protein A domain Glyco_hydro_61 PF03443.14 KXH41688.1 - 6.7e-57 192.7 0.2 8.4e-57 192.4 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Peptidase_M20 PF01546.28 KXH41689.1 - 1.2e-35 123.1 0.0 1.5e-35 122.8 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KXH41689.1 - 8.9e-05 22.4 0.0 0.00027 20.8 0.0 1.8 2 1 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KXH41689.1 - 0.00095 18.9 0.0 0.0021 17.8 0.0 1.5 2 0 0 2 2 2 1 Peptidase family M28 EHN PF06441.12 KXH41690.1 - 1.4e-37 128.3 2.1 3.3e-36 123.9 0.1 2.3 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 KXH41690.1 - 3.2e-13 49.9 0.0 4.9e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXH41690.1 - 0.00012 22.7 0.7 0.00025 21.7 0.7 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family MIP PF00230.20 KXH41691.1 - 7.6e-45 153.4 15.6 9.4e-45 153.1 15.6 1.0 1 0 0 1 1 1 1 Major intrinsic protein Fungal_trans PF04082.18 KXH41692.1 - 9.2e-11 41.3 9.0 2.1e-07 30.3 2.2 2.3 1 1 1 2 2 2 2 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KXH41692.1 - 0.00011 22.4 1.5 0.00011 22.4 1.5 2.6 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXH41692.1 - 0.0011 19.6 1.1 0.0011 19.6 1.1 3.0 2 0 0 2 2 2 1 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KXH41692.1 - 0.1 13.1 9.7 1.7 9.3 6.6 2.5 2 0 0 2 2 2 0 Zinc-finger double domain SUIM_assoc PF16619.5 KXH41700.1 - 3.9 7.6 6.2 6.5 6.9 1.1 2.6 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Not1 PF04054.15 KXH41701.1 - 3.3e-125 417.8 0.0 6.9e-125 416.8 0.0 1.6 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 KXH41701.1 - 1.5e-92 309.1 2.4 1.5e-92 309.1 2.4 1.8 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain DUF3819 PF12842.7 KXH41701.1 - 2.6e-49 166.9 1.8 2.6e-49 166.9 1.8 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3819) CNOT1_TTP_bind PF16417.5 KXH41701.1 - 2.8e-42 144.0 0.0 8.4e-42 142.5 0.0 1.7 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 TTP binding domain CNOT1_HEAT PF16418.5 KXH41701.1 - 9.5e-39 132.9 5.9 1.3e-38 132.4 1.5 2.7 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 HEAT repeat DOPA_dioxygen PF08883.11 KXH41702.1 - 1.4e-42 144.2 0.2 2.4e-42 143.5 0.2 1.4 1 1 0 1 1 1 1 Dopa 4,5-dioxygenase family Rad4 PF03835.15 KXH41703.1 - 1.2e-31 109.4 0.3 2.9e-31 108.2 0.3 1.6 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.9 KXH41703.1 - 4.9e-27 94.1 0.1 1.5e-26 92.6 0.2 1.8 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 KXH41703.1 - 6.6e-22 77.1 0.0 1.6e-21 75.9 0.0 1.7 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 KXH41703.1 - 8.1e-16 58.7 4.9 3.9e-15 56.5 0.1 3.4 2 1 0 2 2 2 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.19 KXH41703.1 - 0.0014 19.0 0.1 0.019 15.4 0.1 2.8 1 1 0 1 1 1 1 Transglutaminase-like superfamily Zn_clus PF00172.18 KXH41704.1 - 2.6e-10 40.2 12.0 4e-10 39.7 12.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXH41704.1 - 0.0093 15.0 0.0 0.018 14.1 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain MARVEL PF01284.23 KXH41776.1 - 0.00012 22.2 16.9 0.00019 21.4 16.9 1.3 1 0 0 1 1 1 1 Membrane-associating domain FAS_I_H PF18314.1 KXH41777.1 - 1.6e-78 263.0 0.6 3.3e-78 262.0 0.1 1.9 2 0 0 2 2 2 1 Fatty acid synthase type I helical domain Fas_alpha_ACP PF18325.1 KXH41777.1 - 3.5e-75 251.8 0.0 7.2e-75 250.8 0.0 1.6 1 0 0 1 1 1 1 Fatty acid synthase subunit alpha Acyl carrier domain ketoacyl-synt PF00109.26 KXH41777.1 - 2.3e-20 73.3 0.1 4.8e-20 72.2 0.1 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACPS PF01648.20 KXH41777.1 - 3.2e-19 69.1 0.0 7.5e-19 68.0 0.0 1.7 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.22 KXH41777.1 - 9.1e-12 45.0 0.1 3e-11 43.3 0.0 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.25 KXH41777.1 - 6.8e-05 22.4 0.0 0.00018 21.1 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXH41777.1 - 0.011 15.6 0.0 0.036 14.0 0.0 1.8 1 0 0 1 1 1 0 KR domain Ribosomal_S4 PF00163.19 KXH41777.1 - 0.1 13.5 0.3 0.38 11.7 0.3 2.0 1 0 0 1 1 1 0 Ribosomal protein S4/S9 N-terminal domain DUF1729 PF08354.10 KXH41778.1 - 6e-153 508.9 0.0 8.9e-153 508.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) Acyl_transf_1 PF00698.21 KXH41778.1 - 3.7e-89 299.4 0.0 6.3e-88 295.3 0.0 2.7 3 0 0 3 3 3 1 Acyl transferase domain FAS_meander PF17951.1 KXH41778.1 - 1.3e-55 187.2 0.0 4.5e-55 185.5 0.0 2.0 2 0 0 2 2 2 1 Fatty acid synthase meander beta sheet domain FAS_N PF17828.1 KXH41778.1 - 3.2e-40 137.1 0.0 6.7e-40 136.1 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta MaoC_dehydratas PF01575.19 KXH41778.1 - 5.1e-38 129.4 0.0 1.1e-37 128.3 0.0 1.6 1 0 0 1 1 1 1 MaoC like domain SAT PF16073.5 KXH41778.1 - 5.5e-36 124.5 0.0 1.6e-35 122.9 0.0 1.8 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis MaoC_dehydrat_N PF13452.6 KXH41778.1 - 4e-24 85.2 0.0 1.4e-23 83.5 0.0 2.0 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase NMO PF03060.15 KXH41778.1 - 0.00076 19.0 0.1 0.0051 16.2 0.1 2.2 1 1 0 1 1 1 1 Nitronate monooxygenase Amidohydro_1 PF01979.20 KXH41779.1 - 2.5e-76 257.3 0.0 2.9e-76 257.0 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KXH41779.1 - 1.2e-08 34.9 0.3 6.5e-06 25.9 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family DUF2802 PF10975.8 KXH41779.1 - 0.083 13.0 0.3 0.55 10.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2802) Lipoxygenase PF00305.19 KXH41780.1 - 4.9e-28 98.0 0.0 8.6e-28 97.2 0.0 1.4 1 0 0 1 1 1 1 Lipoxygenase Dioxygenase_C PF00775.21 KXH41781.1 - 1.6e-06 27.7 0.0 6.7e-05 22.4 0.0 2.4 2 0 0 2 2 2 2 Dioxygenase MFS_1 PF07690.16 KXH41782.1 - 1.3e-21 76.9 20.8 3.2e-21 75.6 20.6 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH41782.1 - 9.3e-09 34.7 2.4 9.3e-09 34.7 2.4 2.2 3 0 0 3 3 3 1 Sugar (and other) transporter DUF1523 PF07509.11 KXH41782.1 - 0.066 12.6 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1523) TPPK_C PF12555.8 KXH41782.1 - 0.88 9.7 4.2 0.38 10.8 0.2 2.5 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal MFS_1 PF07690.16 KXH41783.1 - 1.5e-42 145.8 51.1 1e-41 143.1 51.1 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 KXH41783.1 - 0.041 12.2 0.2 0.041 12.2 0.2 2.7 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family TspO_MBR PF03073.15 KXH41783.1 - 8.2 6.5 15.4 0.1 12.7 4.7 3.1 2 1 1 3 3 3 0 TspO/MBR family Fungal_trans PF04082.18 KXH41785.1 - 2e-28 99.2 0.0 3e-28 98.6 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain p450 PF00067.22 KXH41786.1 - 2.3e-43 148.6 0.0 6.4e-42 143.9 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 ANP PF00212.18 KXH41786.1 - 0.17 12.1 0.6 0.37 11.0 0.1 1.9 2 0 0 2 2 2 0 Atrial natriuretic peptide AMP-binding PF00501.28 KXH41787.1 - 3.1e-87 292.9 0.0 4.7e-87 292.3 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXH41787.1 - 4.2e-19 69.3 0.0 7.8e-19 68.4 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ketoacyl-synt PF00109.26 KXH41788.1 - 2.2e-66 224.0 0.1 5.8e-66 222.7 0.0 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 KXH41788.1 - 1.2e-64 218.8 0.0 1.9e-64 218.2 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 KXH41788.1 - 2.2e-57 194.6 0.0 3.8e-57 193.8 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 KXH41788.1 - 1.1e-55 188.3 0.1 2.4e-55 187.2 0.1 1.6 1 0 0 1 1 1 1 KR domain Ketoacyl-synt_C PF02801.22 KXH41788.1 - 7.1e-31 106.7 0.0 1.6e-30 105.6 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KXH41788.1 - 1.5e-23 83.4 0.0 3.4e-23 82.2 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N PF00107.26 KXH41788.1 - 4.5e-10 39.6 0.0 3.1e-09 36.9 0.0 2.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase adh_short PF00106.25 KXH41788.1 - 2.6e-08 33.6 0.0 6.6e-08 32.2 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase ADH_zinc_N_2 PF13602.6 KXH41788.1 - 8.8e-06 26.8 0.0 4.8e-05 24.4 0.0 2.4 2 0 0 2 2 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXH41788.1 - 0.003 17.4 0.0 0.0084 16.0 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Thiolase_N PF00108.23 KXH41788.1 - 0.0032 16.9 0.1 0.0078 15.6 0.1 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_31 PF13847.6 KXH41788.1 - 0.0091 15.8 0.0 0.031 14.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain adh_short_C2 PF13561.6 KXH41788.1 - 0.018 14.6 0.0 0.038 13.5 0.0 1.5 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase TgMIC1 PF11476.8 KXH41789.1 - 0.11 12.2 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Toxoplasma gondii micronemal protein 1 TgMIC1 Peptidase_M20 PF01546.28 KXH41789.1 - 0.18 11.5 0.0 0.18 11.5 0.0 1.3 1 1 0 1 1 1 0 Peptidase family M20/M25/M40 adh_short PF00106.25 KXH41790.1 - 7.4e-40 136.5 0.0 1e-39 136.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXH41790.1 - 7.5e-22 78.0 0.0 1e-21 77.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH41790.1 - 7.8e-10 38.9 0.0 1.1e-09 38.4 0.0 1.2 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 KXH41790.1 - 0.0016 18.7 0.1 0.0039 17.5 0.1 1.7 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 KXH41790.1 - 0.0027 17.2 0.3 0.0076 15.7 0.3 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KXH41790.1 - 0.0055 16.6 0.0 0.0087 16.0 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding DUF1776 PF08643.10 KXH41790.1 - 0.017 14.5 0.0 0.025 13.9 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) ADH_zinc_N PF00107.26 KXH41790.1 - 0.1 12.5 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase MOZ_SAS PF01853.18 KXH41792.1 - 2.9e-51 173.7 0.0 7.8e-51 172.3 0.0 1.7 1 1 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 KXH41792.1 - 7.2e-09 35.1 0.6 0.0017 18.0 0.5 2.4 2 0 0 2 2 2 2 MYST family zinc finger domain PBCV_basic_adap PF08789.10 KXH41792.1 - 0.3 11.2 3.4 0.24 11.6 1.5 1.8 2 0 0 2 2 2 0 PBCV-specific basic adaptor domain Pox_Ag35 PF03286.14 KXH41792.1 - 1.8 8.3 6.7 0.24 11.2 0.4 2.3 2 0 0 2 2 2 0 Pox virus Ag35 surface protein LRR_6 PF13516.6 KXH41793.1 - 3.6e-14 51.5 3.6 0.043 13.9 0.0 7.0 7 0 0 7 7 7 5 Leucine Rich repeat LRR_1 PF00560.33 KXH41793.1 - 0.00086 19.5 0.2 6.2 7.8 0.0 4.9 5 0 0 5 5 5 1 Leucine Rich Repeat LRR_4 PF12799.7 KXH41793.1 - 0.11 12.9 2.3 59 4.3 0.0 4.6 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) K_channel_TID PF07941.11 KXH41794.1 - 0.033 14.7 2.4 0.033 14.7 2.4 3.2 4 0 0 4 4 4 0 Potassium channel Kv1.4 tandem inactivation domain PAXX PF15384.6 KXH41796.1 - 0.66 9.6 3.6 0.16 11.6 0.2 1.7 2 0 0 2 2 2 0 PAXX, PAralog of XRCC4 and XLF, also called C9orf142 Oxysterol_BP PF01237.18 KXH41796.1 - 1.8 7.3 13.7 0.078 11.8 6.3 2.3 2 1 0 2 2 2 0 Oxysterol-binding protein TBCC PF07986.12 KXH41797.1 - 2.9e-29 101.2 0.1 4.3e-29 100.7 0.1 1.3 1 0 0 1 1 1 1 Tubulin binding cofactor C TBCC_N PF16752.5 KXH41797.1 - 3.6e-11 43.5 0.1 7e-11 42.6 0.1 1.4 1 0 0 1 1 1 1 Tubulin-specific chaperone C N-terminal domain RTX PF02382.15 KXH41797.1 - 0.011 15.4 0.3 0.016 14.9 0.3 1.2 1 0 0 1 1 1 0 N-terminal domain in RTX protein F_actin_bind PF08919.10 KXH41797.1 - 0.17 12.0 0.1 2.4 8.3 0.0 2.3 1 1 1 2 2 2 0 F-actin binding NPV_P10 PF05531.12 KXH41797.1 - 0.49 10.9 1.9 6.3 7.3 0.3 2.3 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Med9 PF07544.13 KXH41798.1 - 7e-21 74.1 0.6 1.1e-20 73.4 0.6 1.3 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 Spc29 PF17082.5 KXH41798.1 - 4.2e-05 23.5 0.1 5.6e-05 23.1 0.1 1.1 1 0 0 1 1 1 1 Spindle Pole Component 29 Phage_GP20 PF06810.11 KXH41798.1 - 0.0015 18.4 0.5 0.0021 17.8 0.5 1.2 1 0 0 1 1 1 1 Phage minor structural protein GP20 Fib_alpha PF08702.10 KXH41798.1 - 0.0022 18.2 1.2 0.003 17.7 0.8 1.4 2 0 0 2 2 2 1 Fibrinogen alpha/beta chain family DUF16 PF01519.16 KXH41798.1 - 0.0084 16.6 0.4 0.012 16.0 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function DUF16 NPV_P10 PF05531.12 KXH41798.1 - 0.013 15.9 0.4 0.059 13.8 0.2 1.9 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein UPF0242 PF06785.11 KXH41798.1 - 0.022 14.9 2.0 0.029 14.5 2.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Med21 PF11221.8 KXH41798.1 - 0.034 14.4 3.6 0.043 14.1 3.6 1.3 1 1 0 1 1 1 0 Subunit 21 of Mediator complex FlxA PF14282.6 KXH41798.1 - 0.062 13.3 1.1 0.1 12.6 1.1 1.3 1 0 0 1 1 1 0 FlxA-like protein XhlA PF10779.9 KXH41798.1 - 0.11 12.7 1.3 0.22 11.8 1.3 1.6 1 0 0 1 1 1 0 Haemolysin XhlA SlyX PF04102.12 KXH41798.1 - 0.27 11.9 7.2 0.78 10.4 4.8 2.6 2 1 1 3 3 3 0 SlyX iPGM_N PF06415.13 KXH41799.1 - 3.1e-78 262.2 0.0 4.4e-78 261.6 0.0 1.2 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Metalloenzyme PF01676.18 KXH41799.1 - 2.2e-65 220.5 0.1 2.6e-65 220.3 0.1 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 KXH41799.1 - 8.3e-07 28.7 0.0 9.8e-06 25.2 0.0 2.2 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KXH41799.1 - 0.00012 21.8 0.0 0.00019 21.1 0.0 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase AP_endonuc_2 PF01261.24 KXH41799.1 - 0.0076 15.7 0.0 0.015 14.8 0.0 1.4 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel p450 PF00067.22 KXH41800.1 - 6.3e-28 97.7 0.0 3.6e-24 85.3 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 adh_short_C2 PF13561.6 KXH41801.1 - 1.3e-56 191.8 2.0 1.4e-56 191.6 2.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXH41801.1 - 1.5e-41 142.0 2.0 2.1e-41 141.5 2.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXH41801.1 - 0.00021 21.3 3.0 0.00057 19.8 3.0 1.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KXH41801.1 - 0.00076 19.0 0.7 0.16 11.4 0.2 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 KXH41801.1 - 0.029 14.2 1.4 0.044 13.7 1.4 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 KXH41801.1 - 0.047 13.1 0.2 5.9 6.2 0.0 2.1 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase THF_DHG_CYH_C PF02882.19 KXH41801.1 - 0.08 12.3 0.2 0.13 11.5 0.2 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain HEM4 PF02602.15 KXH41801.1 - 0.15 11.4 1.2 12 5.1 0.0 2.1 2 0 0 2 2 2 0 Uroporphyrinogen-III synthase HemD HET PF06985.11 KXH41802.1 - 5.9e-32 111.0 0.3 1.2e-31 110.1 0.3 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Cpn60_TCP1 PF00118.24 KXH41803.1 - 5.3e-153 510.2 6.0 6e-153 510.0 6.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family GNAT_acetyltran PF12746.7 KXH41803.1 - 0.036 13.6 0.1 0.092 12.3 0.1 1.6 1 0 0 1 1 1 0 GNAT acetyltransferase PNTB_4TM PF12769.7 KXH41803.1 - 0.059 13.8 0.0 0.23 12.0 0.0 2.0 2 0 0 2 2 2 0 4TM region of pyridine nucleotide transhydrogenase, mitoch zf-C2H2 PF00096.26 KXH41804.1 - 7.3e-08 32.4 26.0 0.00059 20.2 5.3 4.2 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KXH41804.1 - 1.5e-06 28.3 18.2 0.0014 18.9 1.9 4.4 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KXH41804.1 - 0.00045 20.8 22.6 0.036 14.9 4.6 4.2 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KXH41804.1 - 0.0026 17.5 7.3 0.033 13.9 1.7 2.7 2 0 0 2 2 2 2 zinc-finger C2H2-type AT_hook PF02178.19 KXH41804.1 - 1.4 9.0 4.0 4.1 7.6 4.0 1.8 1 0 0 1 1 1 0 AT hook motif C1_4 PF07975.12 KXH41804.1 - 6.8 7.0 7.9 16 5.8 7.9 1.7 1 0 0 1 1 1 0 TFIIH C1-like domain Ribosomal_S2 PF00318.20 KXH41805.1 - 1.4e-63 214.0 0.1 8e-63 211.5 0.1 2.3 1 1 0 1 1 1 1 Ribosomal protein S2 CBS PF00571.28 KXH41805.1 - 2e-33 114.6 3.2 8.4e-09 35.7 0.0 5.1 4 0 0 4 4 4 4 CBS domain PB1 PF00564.24 KXH41805.1 - 1.5e-08 34.4 0.3 3.9e-08 33.1 0.0 1.9 2 0 0 2 2 2 1 PB1 domain PBP1_TM PF14812.6 KXH41805.1 - 0.094 13.1 0.1 0.094 13.1 0.1 1.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Conotoxin PF02950.17 KXH41806.1 - 0.068 14.2 1.5 0.099 13.7 1.5 1.4 1 0 0 1 1 1 0 Conotoxin zf-H2C2 PF09337.10 KXH41807.1 - 2.1e-16 59.8 1.0 4.2e-16 58.9 1.0 1.5 1 0 0 1 1 1 1 H2C2 zinc finger Integrase_H2C2 PF17921.1 KXH41807.1 - 2.2e-12 46.9 0.1 5.5e-12 45.6 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain Acetyltransf_4 PF13420.7 KXH41807.1 - 0.00039 20.6 0.0 0.00061 20.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXH41807.1 - 0.00074 19.7 0.0 0.0014 18.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 KXH41807.1 - 0.044 14.5 0.0 0.097 13.3 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF2647 PF10839.8 KXH41807.1 - 0.14 12.2 0.0 0.33 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2647) SNARE PF05739.19 KXH41809.1 - 0.032 14.2 0.1 0.057 13.4 0.1 1.4 1 0 0 1 1 1 0 SNARE domain ABC2_membrane_2 PF12679.7 KXH41809.1 - 0.14 11.4 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein WSC PF01822.19 KXH41810.1 - 5.1e-11 42.6 9.1 1.4e-10 41.3 9.1 1.8 1 0 0 1 1 1 1 WSC domain SKG6 PF08693.10 KXH41810.1 - 3.9e-10 38.9 4.8 3.9e-10 38.9 4.8 2.2 2 0 0 2 2 2 1 Transmembrane alpha-helix domain DUF4366 PF14283.6 KXH41810.1 - 0.00093 19.3 1.2 0.00093 19.3 1.2 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4366) Alpha_GJ PF03229.13 KXH41810.1 - 0.0049 17.4 6.6 0.0049 17.4 6.6 2.1 2 0 0 2 2 2 1 Alphavirus glycoprotein J MGC-24 PF05283.11 KXH41810.1 - 0.0058 17.1 3.3 0.0058 17.1 3.3 2.3 2 1 0 2 2 2 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin FTCD PF02971.14 KXH41810.1 - 0.018 15.1 0.1 0.028 14.5 0.1 1.2 1 0 0 1 1 1 0 Formiminotransferase domain Insulin_TMD PF17870.1 KXH41810.1 - 0.018 15.1 0.0 0.033 14.3 0.0 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment DUF5305 PF17231.2 KXH41810.1 - 0.019 14.4 0.8 0.032 13.6 0.8 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5305) PTP_tm PF18861.1 KXH41810.1 - 0.041 13.9 0.2 0.081 12.9 0.2 1.5 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J Peptidase_M56 PF05569.11 KXH41810.1 - 0.058 12.6 0.1 0.085 12.0 0.1 1.2 1 0 0 1 1 1 0 BlaR1 peptidase M56 Nitrate_red_gam PF02665.14 KXH41810.1 - 0.12 11.9 0.2 0.24 10.9 0.2 1.5 1 0 0 1 1 1 0 Nitrate reductase gamma subunit DUF1230 PF06799.11 KXH41810.1 - 0.14 12.2 0.1 0.26 11.4 0.1 1.3 1 0 0 1 1 1 0 Conserved in the green lineage and diatoms 27 MFS_MOT1 PF16983.5 KXH41810.1 - 1.2 9.6 8.2 0.41 11.1 4.7 1.9 2 0 0 2 2 2 0 Molybdate transporter of MFS superfamily Podoplanin PF05808.11 KXH41810.1 - 1.2 9.2 12.4 0.13 12.3 7.2 1.9 2 0 0 2 2 2 0 Podoplanin CwsA PF10814.8 KXH41810.1 - 1.6 8.9 8.1 0.3 11.3 4.4 1.7 2 0 0 2 2 2 0 Cell wall synthesis protein CwsA Gram_pos_anchor PF00746.21 KXH41810.1 - 4.4 7.3 9.2 0.16 12.0 2.4 2.3 2 1 0 2 2 1 0 LPXTG cell wall anchor motif UQ_con PF00179.26 KXH41812.1 - 4.1e-51 172.3 0.0 4.6e-51 172.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KXH41812.1 - 0.079 12.7 0.0 0.15 11.7 0.0 1.7 1 1 0 1 1 1 0 Prokaryotic E2 family B TPR_2 PF07719.17 KXH41813.1 - 0.00015 21.6 0.0 3.6 7.9 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 KXH41813.1 - 0.0031 17.3 0.0 0.82 9.6 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat UBA PF00627.31 KXH41813.1 - 0.0084 16.0 0.1 0.018 14.9 0.1 1.6 1 0 0 1 1 1 1 UBA/TS-N domain TPR_12 PF13424.6 KXH41813.1 - 0.03 14.6 0.0 0.76 10.1 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat DnaJ PF00226.31 KXH41813.1 - 0.031 14.4 0.0 0.082 13.0 0.0 1.7 1 0 0 1 1 1 0 DnaJ domain KAsynt_C_assoc PF16197.5 KXH41813.1 - 0.11 13.0 0.2 0.3 11.6 0.2 1.7 1 0 0 1 1 1 0 Ketoacyl-synthetase C-terminal extension DUF1996 PF09362.10 KXH41815.1 - 2.9e-81 272.9 0.1 4e-81 272.4 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) FAD_binding_4 PF01565.23 KXH41816.1 - 7.7e-20 71.1 1.9 1.2e-19 70.4 1.9 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KXH41816.1 - 0.0068 16.5 0.0 0.014 15.5 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like Melibiase_2 PF16499.5 KXH41817.1 - 9.8e-51 172.6 6.4 7.1e-38 130.4 1.5 2.3 2 0 0 2 2 2 2 Alpha galactosidase A Melibiase_C PF17801.1 KXH41817.1 - 2.2e-14 53.2 0.7 2.2e-12 46.9 0.1 2.6 2 0 0 2 2 2 2 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 KXH41817.1 - 6.8e-07 28.5 0.4 1.1e-06 27.9 0.0 1.4 2 0 0 2 2 2 1 Melibiase Voldacs PF03517.13 KXH41819.1 - 3.1e-17 63.0 2.0 3.3e-17 62.9 0.1 2.0 2 1 0 2 2 2 1 Regulator of volume decrease after cellular swelling FAD_binding_3 PF01494.19 KXH41821.1 - 9.5e-19 67.8 0.0 2.6e-18 66.4 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KXH41821.1 - 1.1e-05 24.9 0.2 0.06 12.6 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXH41821.1 - 0.0021 18.6 1.1 0.0095 16.5 0.0 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KXH41821.1 - 0.02 14.2 0.1 0.18 11.1 0.1 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.12 KXH41821.1 - 0.029 13.4 0.1 1.6 7.7 0.0 2.8 3 0 0 3 3 3 0 Lycopene cyclase protein SE PF08491.10 KXH41821.1 - 0.047 12.7 0.0 0.15 11.1 0.0 1.7 2 0 0 2 2 2 0 Squalene epoxidase DAO PF01266.24 KXH41821.1 - 0.049 13.2 0.0 0.4 10.2 0.0 2.0 1 1 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXH41821.1 - 0.054 13.7 0.4 0.19 11.9 0.0 2.2 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 KXH41821.1 - 0.087 11.7 0.0 3.4 6.4 0.0 2.7 3 0 0 3 3 3 0 Tryptophan halogenase Fungal_trans PF04082.18 KXH41822.1 - 9e-26 90.5 0.1 1.3e-25 90.0 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 KXH41823.1 - 1.4e-39 136.1 35.4 7.1e-33 114.0 17.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH41823.1 - 1.4e-15 57.2 12.2 7.2e-15 54.8 3.4 2.2 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_4 PF06779.14 KXH41823.1 - 7.8e-06 25.4 7.9 0.014 14.7 0.5 2.3 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB TRI12 PF06609.13 KXH41823.1 - 0.0002 19.9 0.3 0.0002 19.9 0.3 1.4 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) LacY_symp PF01306.19 KXH41823.1 - 0.0046 15.8 0.4 0.0046 15.8 0.4 2.4 3 0 0 3 3 3 1 LacY proton/sugar symporter RTA1 PF04479.13 KXH41824.1 - 7.2e-55 185.8 9.2 7.2e-55 185.8 9.2 1.4 2 0 0 2 2 2 1 RTA1 like protein DUF2721 PF11026.8 KXH41824.1 - 0.22 11.4 0.3 0.22 11.4 0.3 4.3 4 0 0 4 4 4 0 Protein of unknown function (DUF2721) Pyrophosphatase PF00719.19 KXH41826.1 - 1.3e-43 148.6 0.0 2e-43 147.9 0.0 1.3 1 0 0 1 1 1 1 Inorganic pyrophosphatase Abhydrolase_3 PF07859.13 KXH41827.1 - 6.2e-27 94.8 0.0 3.4e-25 89.2 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KXH41827.1 - 4.7e-07 29.0 0.0 6.1e-07 28.6 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase DUF3089 PF11288.8 KXH41827.1 - 0.0034 16.9 0.0 0.0052 16.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3089) PGAP1 PF07819.13 KXH41827.1 - 0.15 11.7 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Sugar_tr PF00083.24 KXH41828.1 - 2.6e-83 280.4 17.9 3e-83 280.2 17.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH41828.1 - 4.2e-24 85.1 42.9 3e-22 79.0 27.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_17 PF00332.18 KXH41829.1 - 3.1e-07 30.3 1.2 4.1e-07 29.9 1.2 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 DUF992 PF06186.11 KXH41829.1 - 0.024 14.5 0.1 0.062 13.1 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF992) FLILHELTA PF10306.9 KXH41831.1 - 2e-29 101.8 0.1 3.4e-29 101.1 0.1 1.4 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA DUF1279 PF06916.13 KXH41831.1 - 0.017 15.7 0.3 0.022 15.3 0.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1279) NDK PF00334.19 KXH41832.1 - 9.3e-53 177.9 0.0 1.3e-52 177.4 0.0 1.2 1 0 0 1 1 1 1 Nucleoside diphosphate kinase COesterase PF00135.28 KXH41833.1 - 1.1e-74 252.2 0.0 2.7e-46 158.5 0.0 2.0 2 0 0 2 2 2 2 Carboxylesterase family ILEI PF15711.5 KXH41833.1 - 0.035 14.6 0.0 0.083 13.4 0.0 1.5 1 0 0 1 1 1 0 Interleukin-like EMT inducer Glyco_hydro_31 PF01055.26 KXH41834.1 - 3.3e-137 458.3 3.7 4.7e-137 457.8 3.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 KXH41834.1 - 3.3e-23 81.8 0.4 9.7e-23 80.3 0.1 2.0 2 0 0 2 2 2 1 Galactose mutarotase-like DUF5110 PF17137.4 KXH41834.1 - 2.5e-07 30.9 0.7 1.6e-06 28.3 0.5 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF5110) ADH_zinc_N PF00107.26 KXH41835.1 - 1.3e-09 38.1 0.1 2.3e-09 37.3 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXH41835.1 - 0.00013 23.0 0.0 0.00025 22.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXH41835.1 - 0.00028 20.8 0.0 0.0006 19.7 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Glyco_hydro_106 PF17132.4 KXH41836.1 - 1.5e-28 99.6 0.3 1e-25 90.2 0.6 3.0 2 1 0 2 2 2 2 alpha-L-rhamnosidase Glyco_hydro_2_N PF02837.18 KXH41836.1 - 1.1e-06 28.7 0.0 3e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Malt_amylase_C PF16657.5 KXH41836.1 - 0.053 13.6 0.0 0.26 11.4 0.0 2.2 1 1 0 1 1 1 0 Maltogenic Amylase, C-terminal domain MS_channel PF00924.18 KXH41837.1 - 3.2e-21 75.8 0.4 5.2e-21 75.2 0.4 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_7 PF13499.6 KXH41837.1 - 0.0036 17.7 1.0 0.016 15.7 0.6 2.3 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 KXH41837.1 - 0.021 14.7 0.2 0.37 10.9 0.1 2.6 2 0 0 2 2 2 0 EF-hand domain EF-hand_1 PF00036.32 KXH41837.1 - 0.031 13.8 0.3 0.094 12.3 0.3 1.9 1 0 0 1 1 1 0 EF hand Cecropin PF00272.19 KXH41837.1 - 0.15 11.8 3.7 0.43 10.3 2.6 2.2 2 0 0 2 2 2 0 Cecropin family EF-hand_5 PF13202.6 KXH41837.1 - 0.15 11.6 0.2 0.46 10.1 0.2 1.7 1 0 0 1 1 1 0 EF hand Tyrosinase PF00264.20 KXH41838.1 - 8.5e-35 121.0 0.8 1.2e-34 120.5 0.8 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase zf-C2H2_4 PF13894.6 KXH41841.1 - 0.012 16.3 1.0 0.023 15.5 1.0 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KXH41841.1 - 0.06 13.8 1.6 0.12 12.9 1.6 1.4 1 0 0 1 1 1 0 Zinc finger, C2H2 type Glyco_hydro_61 PF03443.14 KXH41842.1 - 7.2e-46 156.7 0.0 1.2e-45 156.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 AT_hook PF02178.19 KXH41844.1 - 0.02 14.7 10.3 1.6 8.8 0.2 4.8 3 0 0 3 3 3 0 AT hook motif PBP1_TM PF14812.6 KXH41844.1 - 4 7.9 7.9 4.3 7.8 3.9 2.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PLA2_B PF01735.18 KXH41845.1 - 4.5e-193 642.1 0.3 5.2e-193 641.9 0.3 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain DUF4658 PF15555.6 KXH41847.1 - 0.024 14.8 0.0 0.04 14.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4658) DUF1180 PF06679.12 KXH41847.1 - 0.1 13.0 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) CMD PF02627.20 KXH41850.1 - 0.0003 20.8 0.0 0.0012 18.8 0.0 2.0 3 0 0 3 3 3 1 Carboxymuconolactone decarboxylase family zf-rbx1 PF12678.7 KXH41851.1 - 1.1e-09 38.4 3.9 2e-09 37.6 3.9 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KXH41851.1 - 1.6e-09 37.9 4.9 3.1e-09 37.0 4.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KXH41851.1 - 4e-06 26.6 2.7 6.9e-06 25.8 2.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXH41851.1 - 9.6e-06 25.5 2.2 1.8e-05 24.6 2.2 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KXH41851.1 - 5.8e-05 23.0 1.9 0.00014 21.8 2.0 1.6 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KXH41851.1 - 0.00028 20.7 6.8 0.0041 17.0 7.1 2.1 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KXH41851.1 - 0.00029 20.4 0.4 0.00062 19.3 0.4 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_2 PF13923.6 KXH41851.1 - 0.0004 20.2 2.3 0.0004 20.2 2.3 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KXH41851.1 - 0.007 16.4 2.6 0.017 15.1 2.6 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 KXH41851.1 - 0.014 15.2 4.0 0.036 13.9 4.1 1.6 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 KXH41851.1 - 0.051 13.3 1.5 0.2 11.4 1.5 2.0 1 1 0 1 1 1 0 RING-like zinc finger zf-C3HC4_4 PF15227.6 KXH41851.1 - 0.13 12.5 1.1 0.25 11.5 1.1 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 KXH41851.1 - 0.28 11.4 1.9 0.75 10.0 1.9 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.6 KXH41851.1 - 1.4 8.8 3.3 3.3 7.6 3.3 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Glyco_transf_8 PF01501.20 KXH41852.1 - 2.9e-23 82.7 0.5 6.9e-22 78.2 0.5 2.1 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 KXH41852.1 - 0.035 13.5 0.0 0.057 12.8 0.0 1.3 1 0 0 1 1 1 0 Mannosyltransferase putative Cation_efflux PF01545.21 KXH41854.1 - 4.5e-15 55.9 7.0 6e-15 55.5 7.0 1.2 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KXH41854.1 - 3.1e-10 40.0 0.2 8.1e-10 38.7 0.2 1.6 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter Hydrolase_4 PF12146.8 KXH41855.1 - 2e-49 168.0 0.0 2.5e-49 167.7 0.0 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KXH41855.1 - 4.7e-12 47.0 0.1 5.8e-12 46.7 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXH41855.1 - 8.8e-11 41.9 0.4 3.2e-10 40.1 0.1 1.8 2 1 0 2 2 2 1 alpha/beta hydrolase fold Esterase PF00756.20 KXH41855.1 - 0.055 13.1 0.0 0.087 12.5 0.0 1.4 1 1 0 1 1 1 0 Putative esterase ABC_membrane PF00664.23 KXH41856.1 - 4.7e-49 167.5 5.6 6.2e-49 167.1 5.6 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KXH41856.1 - 5.1e-33 114.5 0.0 1.1e-32 113.5 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KXH41856.1 - 0.0003 20.3 0.1 0.0068 15.9 0.0 2.2 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KXH41856.1 - 0.004 17.4 0.1 0.029 14.7 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 KXH41856.1 - 0.015 15.7 0.3 0.21 12.0 0.3 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KXH41856.1 - 0.017 15.5 0.1 0.053 13.9 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain ABC_ATPase PF09818.9 KXH41856.1 - 0.025 13.4 0.1 0.042 12.6 0.1 1.3 1 0 0 1 1 1 0 Predicted ATPase of the ABC class AAA_5 PF07728.14 KXH41856.1 - 0.07 13.1 0.1 0.27 11.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.6 KXH41856.1 - 0.079 12.7 0.1 0.2 11.4 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sigma54_activ_2 PF14532.6 KXH41856.1 - 0.12 12.4 0.0 0.76 9.9 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF4131 PF13567.6 KXH41856.1 - 0.18 11.5 0.6 0.92 9.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) IstB_IS21 PF01695.17 KXH41856.1 - 0.22 11.2 0.5 1.7 8.4 0.0 2.4 2 1 1 3 3 3 0 IstB-like ATP binding protein SbcCD_C PF13558.6 KXH41856.1 - 0.26 11.6 1.5 3.1 8.1 1.5 2.5 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit CTD_bind PF04818.13 KXH41857.1 - 2.8e-17 63.3 0.2 7.4e-17 61.9 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase II-binding domain. CREPT PF16566.5 KXH41857.1 - 0.0097 16.1 0.1 0.024 14.8 0.1 1.6 1 0 0 1 1 1 1 Cell-cycle alteration and expression-elevated protein in tumour Clathrin_lg_ch PF01086.17 KXH41858.1 - 8.6e-74 248.5 4.3 9.6e-74 248.3 4.3 1.0 1 0 0 1 1 1 1 Clathrin light chain DUF4051 PF13260.6 KXH41858.1 - 0.49 10.2 2.1 0.86 9.4 2.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4051) CR6_interact PF10147.9 KXH41858.1 - 1 9.0 10.8 0.19 11.4 6.4 1.8 2 0 0 2 2 2 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 COX7a PF02238.15 KXH41859.1 - 6e-19 68.2 1.1 3.1e-16 59.5 0.1 2.1 2 0 0 2 2 2 2 Cytochrome c oxidase subunit VII PDH PF02153.17 KXH41859.1 - 0.23 10.4 0.0 0.29 10.1 0.0 1.1 1 0 0 1 1 1 0 Prephenate dehydrogenase PPR_2 PF13041.6 KXH41860.1 - 0.015 15.5 0.0 0.3 11.3 0.0 2.5 2 0 0 2 2 2 0 PPR repeat family HRDC PF00570.23 KXH41860.1 - 0.028 14.4 0.0 0.69 9.9 0.0 2.6 2 0 0 2 2 2 0 HRDC domain PPR PF01535.20 KXH41860.1 - 0.068 13.4 0.0 0.83 10.0 0.0 2.5 2 0 0 2 2 2 0 PPR repeat ANAPC3 PF12895.7 KXH41860.1 - 0.096 12.9 0.0 2.5 8.4 0.0 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 SNARE PF05739.19 KXH41861.1 - 6.1e-16 58.2 0.8 1.2e-15 57.2 0.8 1.6 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 KXH41861.1 - 3.7e-05 23.5 10.6 0.00036 20.2 10.6 2.0 1 1 0 1 1 1 1 Syntaxin MCPsignal PF00015.21 KXH41861.1 - 0.0074 16.1 7.9 0.27 11.0 1.4 2.6 3 0 0 3 3 3 2 Methyl-accepting chemotaxis protein (MCP) signalling domain Sporozoite_P67 PF05642.11 KXH41861.1 - 0.016 13.3 0.1 0.021 13.0 0.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DASH_Dad1 PF08649.10 KXH41861.1 - 1.5 9.0 3.0 8.4 6.7 0.0 2.9 3 0 0 3 3 3 0 DASH complex subunit Dad1 EF-hand_1 PF00036.32 KXH41862.1 - 2.4e-41 136.2 12.9 9.5e-10 37.3 0.9 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KXH41862.1 - 9.2e-36 122.1 7.0 5.2e-19 68.5 2.2 2.4 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.6 KXH41862.1 - 1.6e-34 117.5 11.9 3.1e-15 55.8 0.6 4.1 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 KXH41862.1 - 1.6e-30 102.4 8.1 2.3e-09 36.4 0.2 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KXH41862.1 - 1.3e-25 87.7 10.6 3.2e-06 26.4 0.3 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 KXH41862.1 - 2.3e-16 59.9 0.4 3.1e-09 37.0 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 KXH41862.1 - 3e-09 37.2 0.3 0.0022 18.3 0.1 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KXH41862.1 - 5.9e-09 35.8 1.9 0.001 19.0 0.2 2.4 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand UPF0154 PF03672.13 KXH41862.1 - 1.7e-06 27.9 0.1 0.0099 15.9 0.0 3.0 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.10 KXH41862.1 - 9.5e-06 25.6 1.6 3.1e-05 24.0 0.2 2.2 2 1 0 2 2 2 1 Ca2+ insensitive EF hand EF-hand_11 PF08976.11 KXH41862.1 - 0.00013 22.8 0.2 0.003 18.4 0.1 2.2 1 1 1 2 2 2 1 EF-hand domain TerB PF05099.13 KXH41862.1 - 0.00021 21.3 0.7 0.47 10.4 0.0 2.4 1 1 1 2 2 2 2 Tellurite resistance protein TerB Caleosin PF05042.13 KXH41862.1 - 0.00084 19.3 1.8 0.55 10.1 0.0 3.5 1 1 3 4 4 4 1 Caleosin related protein RNA_pol_Rpb4 PF03874.16 KXH41862.1 - 0.0023 18.3 2.3 0.69 10.3 0.2 2.8 3 1 0 3 3 2 2 RNA polymerase Rpb4 Dockerin_1 PF00404.18 KXH41862.1 - 0.0071 16.5 6.6 0.47 10.7 0.7 2.9 1 1 2 3 3 3 2 Dockerin type I domain DUF5580 PF17743.1 KXH41862.1 - 0.0073 14.9 0.0 0.0073 14.9 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5580) SurA_N_2 PF13623.6 KXH41862.1 - 0.015 15.1 1.1 0.43 10.4 0.2 2.2 1 1 1 2 2 2 0 SurA N-terminal domain EF-hand_14 PF17959.1 KXH41862.1 - 0.019 15.3 0.5 8.1 6.9 0.1 2.4 1 1 1 2 2 2 0 EF-hand domain Syntaxin PF00804.25 KXH41862.1 - 0.024 14.3 1.0 5.3 6.7 0.1 2.2 2 1 0 2 2 2 0 Syntaxin DUF4497 PF14924.6 KXH41862.1 - 0.025 15.0 0.0 9.9 6.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4497) Toprim_4 PF13662.6 KXH41862.1 - 0.028 14.9 0.1 1.4 9.5 0.0 2.4 2 1 0 2 2 2 0 Toprim domain Poly_export PF02563.16 KXH41862.1 - 0.033 14.4 0.0 0.23 11.7 0.0 2.4 2 1 0 2 2 2 0 Polysaccharide biosynthesis/export protein RuvA_C PF07499.13 KXH41862.1 - 0.089 13.3 0.1 10 6.6 0.0 3.0 3 0 0 3 3 3 0 RuvA, C-terminal domain MotA_activ PF09114.10 KXH41862.1 - 0.089 12.9 0.3 1.2 9.3 0.0 2.3 1 1 0 2 2 2 0 Transcription factor MotA, activation domain dCache_2 PF08269.11 KXH41862.1 - 0.09 11.9 0.1 1.4 8.1 0.1 2.2 1 1 1 2 2 2 0 Cache domain RloB PF13707.6 KXH41862.1 - 0.14 12.3 1.2 0.87 9.8 0.2 2.0 1 1 1 2 2 2 0 RloB-like protein DUF5132 PF17195.4 KXH41862.1 - 0.18 11.9 0.5 24 5.1 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF5132) bZIP_2 PF07716.15 KXH42005.1 - 2.1e-12 46.9 12.2 3.3e-12 46.3 12.2 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 KXH42005.1 - 0.023 14.8 11.6 0.023 14.8 11.6 1.8 1 1 1 2 2 2 0 bZIP transcription factor TSC22 PF01166.18 KXH42005.1 - 0.058 13.7 1.2 0.14 12.5 0.7 1.9 1 1 1 2 2 2 0 TSC-22/dip/bun family TssO PF17561.2 KXH42005.1 - 0.087 12.9 3.5 0.12 12.5 3.5 1.2 1 0 0 1 1 1 0 Type VI secretion system, TssO bZIP_Maf PF03131.17 KXH42005.1 - 0.18 12.4 8.5 0.19 12.3 7.3 1.6 1 1 0 1 1 1 0 bZIP Maf transcription factor XhlA PF10779.9 KXH42005.1 - 0.24 11.6 2.9 0.57 10.4 2.9 1.6 1 0 0 1 1 1 0 Haemolysin XhlA FapA PF03961.13 KXH42005.1 - 0.33 9.5 5.2 0.39 9.3 5.2 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A YcbB PF08664.10 KXH42005.1 - 0.77 9.8 5.9 1.8 8.6 0.1 2.2 2 0 0 2 2 2 0 YcbB domain U1snRNP70_N PF12220.8 KXH42005.1 - 6.4 7.5 15.1 5.2 7.8 11.0 2.5 2 1 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal VWA PF00092.28 KXH42007.1 - 6.6e-05 23.2 0.0 0.00029 21.2 0.0 1.8 1 1 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.9 KXH42007.1 - 0.0034 17.5 0.0 0.0078 16.3 0.0 1.6 1 1 0 1 1 1 1 vWA found in TerF C terminus ORC6 PF05460.13 KXH42007.1 - 3.3 6.9 5.8 4.5 6.5 5.8 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Aminotran_1_2 PF00155.21 KXH42008.1 - 2.9e-34 118.8 0.0 3.5e-34 118.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II EST1_DNA_bind PF10373.9 KXH42018.1 - 1.5e-13 50.9 0.0 2.8e-13 50.0 0.0 1.5 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain zf-C2H2_4 PF13894.6 KXH42020.1 - 0.051 14.4 0.7 0.19 12.6 0.7 2.0 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KXH42020.1 - 0.053 14.0 0.4 0.21 12.1 0.4 2.1 1 0 0 1 1 1 0 Zinc finger, C2H2 type Fungal_trans PF04082.18 KXH42021.1 - 1.8e-17 63.3 0.0 2.8e-17 62.6 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH42021.1 - 9.6e-07 28.8 6.7 1.9e-06 27.9 6.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.26 KXH42022.1 - 3e-14 52.6 17.8 0.00021 21.5 0.4 4.3 4 1 1 5 5 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXH42022.1 - 1.3e-08 34.9 17.9 0.0013 19.4 0.3 4.5 5 0 0 5 5 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KXH42022.1 - 9.2e-05 22.7 6.6 0.00073 19.9 0.8 4.1 5 0 0 5 5 4 2 Zinc-finger double domain zf-C2H2_6 PF13912.6 KXH42022.1 - 0.0053 16.7 9.8 0.067 13.2 0.1 4.0 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KXH42022.1 - 0.0067 16.7 7.6 9.5 6.6 0.1 4.4 2 1 1 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 KXH42022.1 - 0.041 13.8 0.3 0.19 11.7 0.3 2.2 1 0 0 1 1 1 0 zinc-finger of a C2HC-type zf-C2H2_11 PF16622.5 KXH42022.1 - 0.047 13.5 0.1 0.047 13.5 0.1 2.8 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-C2H2_aberr PF17017.5 KXH42022.1 - 0.1 12.7 4.4 0.37 10.9 4.4 1.9 1 1 1 2 2 2 0 Aberrant zinc-finger zf-CHCC PF10276.9 KXH42022.1 - 0.11 12.6 0.9 0.23 11.5 0.1 2.0 2 0 0 2 2 2 0 Zinc-finger domain zf-BED PF02892.15 KXH42022.1 - 0.15 12.1 7.7 0.097 12.7 4.4 2.3 2 0 0 2 2 2 0 BED zinc finger zf-met PF12874.7 KXH42022.1 - 0.2 12.1 6.3 4.9 7.7 0.1 3.9 4 0 0 4 4 3 0 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 KXH42022.1 - 0.48 10.8 5.8 0.22 11.8 2.3 2.2 2 0 0 2 2 2 0 C2H2-type zinc ribbon zf-LYAR PF08790.11 KXH42022.1 - 0.98 9.4 5.9 5.8 6.9 0.1 3.5 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger zf-C2H2_2 PF12756.7 KXH42022.1 - 1.3 9.4 5.9 3.7 7.9 4.7 2.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) RNA_pol_Rpb1_5 PF04998.17 KXH42023.1 - 9.8e-87 290.8 0.0 1.8e-86 289.9 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 KXH42023.1 - 1.1e-68 230.7 0.1 3.8e-68 228.9 0.1 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_1 PF04997.12 KXH42023.1 - 1.7e-35 122.9 2.1 6.7e-34 117.6 1.8 3.0 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_3 PF04983.18 KXH42023.1 - 3e-33 115.0 0.0 8.8e-33 113.5 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 KXH42023.1 - 1.5e-16 60.3 0.2 1.1e-15 57.5 0.1 2.6 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 Cutinase PF01083.22 KXH42041.1 - 3.4e-30 105.3 0.0 3.6e-28 98.7 0.0 2.3 1 1 1 2 2 2 1 Cutinase Jacalin PF01419.17 KXH42041.1 - 4.9e-06 26.5 0.6 0.00017 21.5 0.2 2.1 1 1 1 2 2 2 1 Jacalin-like lectin domain DUF3089 PF11288.8 KXH42041.1 - 0.00041 19.9 0.0 0.00072 19.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3089) PE-PPE PF08237.11 KXH42041.1 - 0.0075 15.8 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 PE-PPE domain VirJ PF06057.11 KXH42041.1 - 0.048 13.5 0.0 0.17 11.8 0.0 1.8 2 0 0 2 2 2 0 Bacterial virulence protein (VirJ) Lipase_3 PF01764.25 KXH42041.1 - 0.18 11.7 0.0 0.31 10.9 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) ABC_tran PF00005.27 KXH42042.1 - 2.2e-36 125.4 0.1 7.7e-17 62.1 0.0 3.1 3 0 0 3 3 2 2 ABC transporter ABC_membrane PF00664.23 KXH42042.1 - 6.9e-35 121.0 19.8 2.5e-24 86.4 4.7 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_16 PF13191.6 KXH42042.1 - 1e-09 39.0 0.4 0.00071 20.0 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.19 KXH42042.1 - 2.2e-09 37.1 0.0 0.00083 18.9 0.0 3.2 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KXH42042.1 - 3.6e-09 37.0 0.3 0.0061 16.8 0.0 3.7 4 0 0 4 4 3 2 AAA domain AAA_25 PF13481.6 KXH42042.1 - 1e-08 35.0 0.4 0.0091 15.6 0.0 3.7 3 0 0 3 3 3 2 AAA domain T2SSE PF00437.20 KXH42042.1 - 1.3e-07 31.0 0.2 0.0078 15.3 0.0 2.5 2 0 0 2 2 2 2 Type II/IV secretion system protein RsgA_GTPase PF03193.16 KXH42042.1 - 9.4e-06 25.6 0.4 0.2 11.5 0.0 2.9 3 0 0 3 3 2 2 RsgA GTPase AAA_21 PF13304.6 KXH42042.1 - 1.7e-05 24.8 5.9 0.11 12.3 0.1 3.7 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 KXH42042.1 - 6.2e-05 23.4 0.2 0.014 15.8 0.1 3.8 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 KXH42042.1 - 6.4e-05 22.5 0.1 0.16 11.5 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_29 PF13555.6 KXH42042.1 - 9.3e-05 22.1 1.0 0.0093 15.7 0.2 2.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain Zeta_toxin PF06414.12 KXH42042.1 - 0.00011 21.5 2.6 0.16 11.2 0.0 4.0 4 0 0 4 4 4 1 Zeta toxin SbcCD_C PF13558.6 KXH42042.1 - 0.00015 21.9 0.3 0.23 11.7 0.0 3.3 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.6 KXH42042.1 - 0.0002 21.5 0.0 0.6 10.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 KXH42042.1 - 0.001 19.4 0.3 1.5 9.2 0.0 3.5 4 0 0 4 4 2 1 RNA helicase Rad17 PF03215.15 KXH42042.1 - 0.0021 18.0 1.4 1.4 8.8 0.3 2.9 3 0 0 3 3 3 1 Rad17 P-loop domain FtsK_SpoIIIE PF01580.18 KXH42042.1 - 0.0022 17.4 0.0 0.007 15.7 0.0 1.8 1 0 0 1 1 1 1 FtsK/SpoIIIE family TsaE PF02367.17 KXH42042.1 - 0.0039 17.2 0.2 0.25 11.3 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 KXH42042.1 - 0.0044 16.8 0.1 0.03 14.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 KXH42042.1 - 0.0052 16.9 0.1 2.3 8.3 0.0 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase ATPase_2 PF01637.18 KXH42042.1 - 0.0059 16.6 0.0 2.6 7.9 0.0 2.5 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_23 PF13476.6 KXH42042.1 - 0.0062 17.1 0.2 0.36 11.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 KXH42042.1 - 0.0079 15.8 4.5 1.2 8.7 0.2 2.9 3 0 0 3 3 3 2 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 KXH42042.1 - 0.017 15.1 3.4 1.6 8.6 0.1 3.2 3 1 0 3 3 2 0 NACHT domain Septin PF00735.18 KXH42042.1 - 0.021 14.1 0.3 2.4 7.4 0.0 2.3 2 0 0 2 2 2 0 Septin AAA_5 PF07728.14 KXH42042.1 - 0.027 14.5 0.4 7.1 6.6 0.1 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.15 KXH42042.1 - 0.03 14.2 0.8 0.99 9.3 0.0 2.4 2 0 0 2 2 2 0 NTPase DUF815 PF05673.13 KXH42042.1 - 0.033 13.4 0.0 5.2 6.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Adeno_IVa2 PF02456.15 KXH42042.1 - 0.036 12.9 0.6 1.3 7.7 0.1 2.3 2 0 0 2 2 2 0 Adenovirus IVa2 protein Viral_helicase1 PF01443.18 KXH42042.1 - 0.036 13.8 0.3 4.9 6.8 0.0 2.6 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase IstB_IS21 PF01695.17 KXH42042.1 - 0.043 13.6 0.2 7.2 6.3 0.0 2.9 3 0 0 3 3 2 0 IstB-like ATP binding protein DUF2474 PF10617.9 KXH42042.1 - 0.065 13.1 1.0 0.34 10.8 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2474) DEAD PF00270.29 KXH42042.1 - 0.066 13.0 0.1 4 7.2 0.0 2.9 3 0 0 3 3 2 0 DEAD/DEAH box helicase TrwB_AAD_bind PF10412.9 KXH42042.1 - 0.073 12.0 1.5 3.3 6.5 0.1 3.2 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain AAA_30 PF13604.6 KXH42042.1 - 0.074 12.8 0.2 7.6 6.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain MobB PF03205.14 KXH42042.1 - 0.095 12.6 1.1 8.3 6.3 0.1 2.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Mg_chelatase PF01078.21 KXH42042.1 - 0.096 12.1 0.1 12 5.2 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DUF3464 PF11947.8 KXH42042.1 - 0.096 12.4 0.1 0.27 11.0 0.1 1.7 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 PduV-EutP PF10662.9 KXH42042.1 - 0.12 12.2 2.2 1.3 8.8 0.1 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_18 PF13238.6 KXH42042.1 - 0.19 12.3 1.1 18 5.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 KXH42042.1 - 0.2 11.7 0.6 1.1 9.3 0.0 2.2 2 0 0 2 2 2 0 Helicase HerA, central domain DUF2929 PF11151.8 KXH42042.1 - 0.51 10.7 5.6 13 6.2 0.4 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2929) Cyclin_N PF00134.23 KXH42043.1 - 1.6e-11 44.0 0.1 4.3e-11 42.7 0.1 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C_2 PF16899.5 KXH42043.1 - 0.0032 17.8 0.6 0.012 16.0 0.3 2.1 2 1 0 2 2 2 1 Cyclin C-terminal domain Las1 PF04031.13 KXH42043.1 - 0.025 14.7 0.9 2 8.5 0.9 2.8 1 1 0 1 1 1 0 Las1-like Turandot PF07240.11 KXH42043.1 - 0.12 12.3 0.1 0.25 11.3 0.1 1.5 1 0 0 1 1 1 0 Stress-inducible humoral factor Turandot TFIIB PF00382.19 KXH42043.1 - 0.14 12.3 0.1 0.14 12.3 0.1 1.8 2 0 0 2 2 2 0 Transcription factor TFIIB repeat Mito_carr PF00153.27 KXH42044.1 - 8.5e-67 221.2 6.5 5.1e-24 84.0 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 KXH42044.1 - 1.7e-22 79.7 6.2 7.2e-12 45.6 1.0 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KXH42044.1 - 2.8e-19 67.1 6.7 8.3e-05 21.9 0.8 4.4 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 KXH42044.1 - 3.1e-16 57.9 7.7 0.00011 21.8 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KXH42044.1 - 3.2e-16 58.0 5.3 1.7e-05 24.1 0.7 3.5 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 KXH42044.1 - 2.3e-08 33.8 6.1 0.0013 18.5 0.5 3.2 2 1 1 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KXH42044.1 - 5.6e-08 33.1 0.2 0.00018 21.8 0.0 2.4 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Serine_protease PF18405.1 KXH42044.1 - 0.028 13.6 2.4 1.1 8.4 0.0 3.0 3 0 0 3 3 3 0 Gammaproteobacterial serine protease EspB_PE PF18625.1 KXH42044.1 - 0.031 14.7 6.0 2.5 8.6 1.7 2.6 2 0 0 2 2 2 0 ESX-1 secreted protein B PE domain EF-hand_4 PF12763.7 KXH42044.1 - 0.36 10.8 5.0 6.3 6.8 0.1 3.6 1 1 2 3 3 3 0 Cytoskeletal-regulatory complex EF hand DUF4097 PF13349.6 KXH42045.1 - 8.4e-06 25.3 0.0 0.00084 18.8 0.0 3.4 2 1 0 2 2 2 2 Putative adhesin ATP_bind_3 PF01171.20 KXH42046.1 - 5.6e-40 137.0 0.0 6.1e-27 94.5 0.0 2.3 2 0 0 2 2 2 2 PP-loop family Mito_carr PF00153.27 KXH42047.1 - 1.8e-45 152.8 7.6 1.3e-19 69.8 0.2 4.2 3 1 0 3 3 3 3 Mitochondrial carrier protein K-cyclin_vir_C PF09080.10 KXH42047.1 - 0.0051 17.2 0.2 0.014 15.8 0.2 1.7 1 0 0 1 1 1 1 K cyclin, C terminal Serine_protease PF18405.1 KXH42047.1 - 0.007 15.6 1.1 0.11 11.6 0.2 2.2 2 0 0 2 2 2 1 Gammaproteobacterial serine protease DUF3337 PF11816.8 KXH42048.1 - 3.1e-55 186.7 0.0 6.4e-55 185.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3337) WD40 PF00400.32 KXH42048.1 - 1.5e-16 60.4 12.7 0.0011 19.7 0.3 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.8 KXH42048.1 - 0.012 14.3 2.1 0.021 13.5 0.0 2.0 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Ribosomal_60s PF00428.19 KXH42048.1 - 4.5 7.9 30.3 6.9 7.3 1.5 4.4 4 0 0 4 4 4 0 60s Acidic ribosomal protein DEAD PF00270.29 KXH42049.1 - 9.3e-46 155.8 0.0 1.6e-45 155.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXH42049.1 - 2.6e-19 69.6 0.0 2.1e-18 66.6 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KXH42049.1 - 6.3e-19 68.0 0.2 1.4e-18 66.8 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KXH42049.1 - 0.00032 20.7 0.0 0.001 19.1 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SWIRM-assoc_2 PF16496.5 KXH42049.1 - 0.28 10.0 13.9 0.49 9.2 13.9 1.3 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal Pox_Ag35 PF03286.14 KXH42049.1 - 3 7.6 18.6 5.1 6.8 18.6 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CMS1 PF14617.6 KXH42049.1 - 4.1 6.7 8.8 1.6 8.0 0.0 2.6 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit FYDLN_acid PF09538.10 KXH42049.1 - 9.5 7.0 15.5 21 5.9 15.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) 6PF2K PF01591.18 KXH42050.1 - 1.8e-79 266.2 0.2 2.3e-79 265.8 0.2 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 KXH42050.1 - 1e-35 123.2 0.0 1.6e-35 122.5 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 KXH42050.1 - 2e-06 28.1 0.0 3.6e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 KXH42050.1 - 0.00016 21.2 0.1 0.00025 20.6 0.1 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 Glyco_hydro_26 PF02156.15 KXH42050.1 - 0.034 13.6 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 26 Adeno_E3_CR1 PF02440.15 KXH42050.1 - 0.14 12.0 0.1 0.33 10.8 0.0 1.6 1 1 0 1 1 1 0 Adenovirus E3 region protein CR1 Asp PF00026.23 KXH42051.1 - 6.8e-38 130.8 0.6 1.1e-37 130.2 0.6 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.6 KXH42051.1 - 8.3e-06 26.4 0.4 0.041 14.5 0.1 3.0 3 0 0 3 3 3 2 Aspartyl protease gag-asp_proteas PF13975.6 KXH42051.1 - 0.032 14.8 0.1 4.3 8.0 0.0 2.9 3 0 0 3 3 3 0 gag-polyprotein putative aspartyl protease TAXi_N PF14543.6 KXH42051.1 - 0.099 12.9 0.8 6.8 6.9 0.1 3.1 3 1 0 3 3 3 0 Xylanase inhibitor N-terminal DUF829 PF05705.14 KXH42052.1 - 1.3e-39 136.5 0.0 1.9e-39 136.0 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Helo_like_N PF17111.5 KXH42053.1 - 0.002 17.5 1.8 0.0032 16.9 1.8 1.3 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins Ank_2 PF12796.7 KXH42053.1 - 0.0078 16.8 0.0 0.033 14.8 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXH42053.1 - 0.021 15.2 0.0 0.049 14.0 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXH42053.1 - 0.022 15.3 0.4 0.37 11.5 0.1 3.0 3 0 0 3 3 3 0 Ankyrin repeat Ank_4 PF13637.6 KXH42053.1 - 0.089 13.4 0.0 0.46 11.1 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeats (many copies) La_HTH_kDCL PF18177.1 KXH42054.1 - 0.11 12.8 0.0 0.22 11.9 0.0 1.4 1 0 0 1 1 1 0 La HTH in kinetoplastid DICER domain zf-C2H2 PF00096.26 KXH42054.1 - 0.11 13.0 0.1 0.11 13.0 0.1 2.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXH42054.1 - 0.38 11.7 2.5 0.86 10.6 0.1 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger DUF2039 PF10217.9 KXH42055.1 - 0.024 15.0 3.9 0.026 14.8 0.5 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) DUF5332 PF17266.2 KXH42055.1 - 0.57 9.9 5.3 0.18 11.5 1.1 1.8 1 1 1 2 2 2 0 Family of unknown function (DUF5332) KH_1 PF00013.29 KXH42056.1 - 9.4e-48 159.9 15.7 7.8e-17 60.9 0.8 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 KXH42056.1 - 6.5e-12 45.1 4.3 0.0034 17.2 0.0 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 KXH42056.1 - 7.4e-08 32.2 7.8 0.16 11.9 0.2 3.4 3 0 0 3 3 3 3 KH domain MOEP19 PF16005.5 KXH42056.1 - 0.0014 18.6 0.0 0.14 12.2 0.0 2.9 3 0 0 3 3 3 1 KH-like RNA-binding domain KH_5 PF13184.6 KXH42056.1 - 0.0082 16.2 5.7 10 6.3 0.1 3.7 3 1 0 3 3 3 3 NusA-like KH domain Baculo_PEP_C PF04513.12 KXH42057.1 - 0.012 15.7 13.9 0.05 13.6 1.2 3.9 3 2 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus ETRAMP PF09716.10 KXH42057.1 - 0.013 15.6 0.2 9.7 6.3 0.0 3.5 4 1 0 4 4 4 0 Malarial early transcribed membrane protein (ETRAMP) TMEM251 PF15190.6 KXH42057.1 - 0.079 12.9 0.9 0.32 11.0 0.9 2.0 1 1 0 1 1 1 0 Transmembrane protein 251 Trp_syntA PF00290.20 KXH42058.1 - 3.6e-96 321.0 0.4 5.6e-96 320.4 0.0 1.5 2 0 0 2 2 2 1 Tryptophan synthase alpha chain PALP PF00291.25 KXH42058.1 - 5.1e-49 167.3 2.5 1.3e-48 166.0 2.6 1.6 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme Ribosomal_L28 PF00830.19 KXH42059.1 - 2.4e-19 69.3 2.2 3.4e-19 68.8 2.2 1.2 1 0 0 1 1 1 1 Ribosomal L28 family TPR_1 PF00515.28 KXH42062.1 - 4.6e-37 124.3 17.2 1.1e-06 28.2 0.2 8.3 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_2 PF07719.17 KXH42062.1 - 4.3e-35 117.0 15.7 3.6e-06 26.7 0.0 8.2 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_11 PF13414.6 KXH42062.1 - 5.2e-29 99.7 16.1 6.8e-09 35.3 0.3 7.2 6 1 1 7 7 7 6 TPR repeat DnaJ PF00226.31 KXH42062.1 - 1.6e-27 95.4 6.3 5.3e-27 93.7 4.0 2.5 2 0 0 2 2 2 1 DnaJ domain TPR_16 PF13432.6 KXH42062.1 - 7e-21 74.6 2.3 0.00019 22.0 0.1 6.1 5 1 0 5 5 5 5 Tetratricopeptide repeat TPR_19 PF14559.6 KXH42062.1 - 1.1e-20 73.8 10.9 1.3e-05 25.6 0.0 6.0 3 2 2 5 5 5 4 Tetratricopeptide repeat ANAPC3 PF12895.7 KXH42062.1 - 9.8e-15 54.6 5.6 1.7e-06 28.1 0.2 3.6 3 0 0 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 KXH42062.1 - 1.5e-14 52.9 15.9 0.00091 19.3 0.5 7.8 9 0 0 9 9 7 4 Tetratricopeptide repeat TPR_14 PF13428.6 KXH42062.1 - 2.5e-14 52.7 9.2 0.00019 22.0 0.0 7.4 5 1 2 7 7 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 KXH42062.1 - 2.9e-14 52.3 11.4 0.0037 17.5 0.0 7.2 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_12 PF13424.6 KXH42062.1 - 6.9e-13 48.7 12.4 0.045 14.0 0.2 6.5 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_9 PF13371.6 KXH42062.1 - 7.3e-12 45.3 6.1 0.02 15.0 0.1 5.1 4 1 1 5 5 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 KXH42062.1 - 8.2e-11 41.1 6.0 0.37 10.9 0.0 7.5 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_6 PF13174.6 KXH42062.1 - 1.3e-06 28.6 16.9 0.087 13.5 0.0 8.3 8 2 1 9 9 7 1 Tetratricopeptide repeat TPR_10 PF13374.6 KXH42062.1 - 3.8e-05 23.4 9.0 0.28 11.1 0.0 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_15 PF13429.6 KXH42062.1 - 0.00017 20.9 9.1 0.24 10.6 0.0 4.4 2 2 2 4 4 4 2 Tetratricopeptide repeat NARP1 PF12569.8 KXH42062.1 - 0.00048 19.2 4.6 0.0017 17.4 0.7 2.9 2 1 1 3 3 3 1 NMDA receptor-regulated protein 1 TPR_4 PF07721.14 KXH42062.1 - 0.0011 19.4 1.4 0.13 13.0 0.0 4.2 4 0 0 4 4 3 1 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 KXH42062.1 - 0.0071 16.8 6.1 7.9 6.9 1.0 4.3 3 1 1 4 4 3 0 Alkyl sulfatase dimerisation ChAPs PF09295.10 KXH42062.1 - 0.015 14.3 0.0 0.028 13.4 0.0 1.4 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_20 PF14561.6 KXH42062.1 - 0.027 14.8 8.8 5.2 7.5 0.0 5.1 3 3 2 5 5 5 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KXH42062.1 - 0.037 14.1 3.7 4.6 7.4 0.0 4.2 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat PPR PF01535.20 KXH42062.1 - 0.05 13.9 0.2 20 5.7 0.0 3.6 4 0 0 4 4 2 0 PPR repeat DUF928 PF06051.12 KXH42062.1 - 0.051 13.4 0.4 0.12 12.2 0.4 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF928) Coatomer_E PF04733.14 KXH42062.1 - 0.055 12.9 0.6 7 6.0 0.0 2.5 2 0 0 2 2 2 0 Coatomer epsilon subunit BTAD PF03704.17 KXH42062.1 - 0.075 13.5 8.0 17 5.8 0.1 4.9 3 2 2 5 5 4 0 Bacterial transcriptional activator domain RPT PF13446.6 KXH42062.1 - 0.12 12.3 0.1 0.77 9.7 0.0 2.4 2 0 0 2 2 1 0 A repeated domain in UCH-protein DUF357 PF04010.13 KXH42062.1 - 2.6 8.2 4.8 2.9 8.0 0.2 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF357) Med10 PF09748.9 KXH42063.1 - 4.5e-47 159.0 0.0 5.2e-47 158.8 0.0 1.0 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex DUF3877 PF12993.7 KXH42063.1 - 0.023 14.6 0.0 0.063 13.1 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function, E. rectale Gene description (DUF3877) Tyrosinase PF00264.20 KXH42065.1 - 2e-31 110.0 0.0 1.1e-30 107.6 0.0 2.0 1 1 1 2 2 2 1 Common central domain of tyrosinase RNA_pol_Rpb6 PF01192.22 KXH42066.1 - 2e-14 53.2 0.9 6.1e-14 51.7 0.9 1.8 1 1 0 1 1 1 1 RNA polymerase Rpb6 zf-C2H2 PF00096.26 KXH42067.1 - 1.6e-30 103.8 48.2 0.00011 22.5 1.0 10.4 10 0 0 10 10 10 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXH42067.1 - 4.7e-21 73.6 50.3 0.046 14.6 0.5 10.9 10 1 0 10 10 10 8 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KXH42067.1 - 2.1e-13 50.0 44.5 0.0025 18.1 1.3 11.0 11 0 0 11 11 11 4 Zinc-finger double domain FOXP-CC PF16159.5 KXH42067.1 - 2.1e-12 47.5 25.1 0.076 13.6 0.3 7.6 4 1 4 8 8 8 5 FOXP coiled-coil domain zf-C2H2_jaz PF12171.8 KXH42067.1 - 7.3e-07 29.3 29.7 0.43 10.9 0.0 9.8 11 0 0 11 11 11 3 Zinc-finger double-stranded RNA-binding zf-C2H2_aberr PF17017.5 KXH42067.1 - 4.7e-06 26.9 14.5 2.9 8.0 0.6 5.6 3 1 3 6 6 6 3 Aberrant zinc-finger zf-C2H2_8 PF15909.5 KXH42067.1 - 6.4e-05 23.2 15.9 0.2 12.0 5.3 4.9 3 1 2 5 5 5 3 C2H2-type zinc ribbon Ogr_Delta PF04606.12 KXH42067.1 - 0.00057 19.8 2.6 0.51 10.4 0.2 4.1 3 1 1 4 4 4 1 Ogr/Delta-like zinc finger DUF4187 PF13821.6 KXH42067.1 - 0.0037 17.0 1.6 0.029 14.1 0.3 2.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4187) zf-met PF12874.7 KXH42067.1 - 0.0098 16.3 21.3 0.072 13.5 0.0 8.2 9 0 0 9 9 9 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KXH42067.1 - 1.2 9.2 11.8 1.3 9.1 0.0 5.0 5 0 0 5 5 5 0 C2H2-type zinc finger RRM_1 PF00076.22 KXH42068.1 - 3e-36 123.1 0.1 4.6e-11 42.4 0.2 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KXH42068.1 - 2.8e-14 52.7 0.0 0.0092 15.8 0.0 4.3 4 0 0 4 4 4 4 Occluded RNA-recognition motif RRM PF10378.9 KXH42068.1 - 6.4e-08 32.2 8.2 6.4e-08 32.2 8.2 3.7 4 1 0 4 4 4 1 Putative RRM domain DUF4523 PF15023.6 KXH42068.1 - 1.7e-06 28.0 0.0 0.0086 15.9 0.0 3.3 3 0 0 3 3 3 2 Protein of unknown function (DUF4523) RRM_7 PF16367.5 KXH42068.1 - 2.7e-06 27.4 0.0 0.027 14.6 0.0 3.9 4 0 0 4 4 4 2 RNA recognition motif RRM_3 PF08777.11 KXH42068.1 - 0.015 15.3 0.2 0.28 11.2 0.1 2.7 3 0 0 3 3 3 0 RNA binding motif RNA_bind PF08675.11 KXH42068.1 - 0.053 13.5 0.8 0.2 11.7 0.0 2.3 3 0 0 3 3 3 0 RNA binding domain Nup35_RRM_2 PF14605.6 KXH42068.1 - 0.06 13.3 0.0 25 5.0 0.0 3.3 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif tRNA-synt_2 PF00152.20 KXH42069.1 - 2.2e-84 283.2 0.0 3.5e-84 282.6 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KXH42069.1 - 1.4e-10 41.0 0.0 2.5e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA_anti_2 PF13742.6 KXH42069.1 - 0.021 15.0 0.0 0.053 13.7 0.0 1.6 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain SPOUT_MTase PF02590.17 KXH42069.1 - 0.029 14.3 0.8 0.062 13.3 0.8 1.5 1 0 0 1 1 1 0 Predicted SPOUT methyltransferase ABC2_membrane PF01061.24 KXH42081.1 - 8.4e-72 241.0 62.1 2e-37 128.6 21.5 2.9 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 KXH42081.1 - 9.2e-36 123.4 0.0 7.1e-17 62.2 0.0 2.7 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KXH42081.1 - 9e-27 92.8 0.3 8.6e-23 80.1 0.0 3.1 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.6 KXH42081.1 - 2.9e-17 63.0 0.8 3.1e-16 59.7 0.3 2.8 2 0 0 2 2 2 1 ABC-transporter N-terminal AAA_33 PF13671.6 KXH42081.1 - 4.9e-07 30.0 0.0 0.0085 16.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KXH42081.1 - 8.7e-07 29.5 0.3 0.021 15.2 0.0 2.9 3 0 0 3 3 3 2 AAA ATPase domain AAA_21 PF13304.6 KXH42081.1 - 9.5e-06 25.6 0.0 0.2 11.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 KXH42081.1 - 1.5e-05 25.6 0.0 0.011 16.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 KXH42081.1 - 1.5e-05 25.4 0.0 0.038 14.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KXH42081.1 - 9.1e-05 22.4 0.1 0.0011 18.9 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 KXH42081.1 - 0.00015 21.4 0.3 0.012 15.3 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_25 PF13481.6 KXH42081.1 - 0.0002 21.0 0.4 0.015 14.8 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KXH42081.1 - 0.00081 19.7 0.1 0.31 11.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 KXH42081.1 - 0.0018 17.8 0.0 0.72 9.2 0.0 3.4 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain NACHT PF05729.12 KXH42081.1 - 0.0033 17.4 0.8 2.1 8.2 0.0 2.4 2 0 0 2 2 2 2 NACHT domain AAA_28 PF13521.6 KXH42081.1 - 0.011 16.0 1.3 0.11 12.7 0.0 2.7 3 0 0 3 3 2 0 AAA domain cobW PF02492.19 KXH42081.1 - 0.018 14.7 2.0 0.38 10.3 0.3 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 KXH42081.1 - 0.032 13.9 1.1 2.2 7.9 0.2 2.4 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 KXH42081.1 - 0.11 12.9 0.8 3.3 8.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KXH42081.1 - 0.33 10.6 1.0 16 5.1 0.1 2.5 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 KXH42081.1 - 0.42 10.6 1.5 5.8 6.9 0.2 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_23 PF13476.6 KXH42081.1 - 0.62 10.5 2.6 0.5 10.8 0.1 2.2 2 0 0 2 2 1 0 AAA domain Wzz PF02706.15 KXH42081.1 - 1.9 8.8 3.6 1.9 8.8 0.0 2.8 3 0 0 3 3 2 0 Chain length determinant protein EBP50_C PF09007.11 KXH42083.1 - 0.22 12.5 7.5 0.14 13.1 2.4 2.6 2 0 0 2 2 2 0 EBP50, C-terminal MFS_1 PF07690.16 KXH42084.1 - 2e-35 122.3 30.9 3e-35 121.8 30.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Cu_amine_oxid PF01179.20 KXH42085.1 - 8.3e-163 542.1 0.0 1e-162 541.8 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 KXH42085.1 - 4.5e-23 81.6 0.2 9.7e-23 80.5 0.2 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 KXH42085.1 - 4.5e-15 55.7 0.0 7.5e-15 54.9 0.0 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain ACTH_domain PF00976.18 KXH42086.1 - 0.2 11.6 1.4 0.47 10.5 1.4 1.7 1 0 0 1 1 1 0 Corticotropin ACTH domain Lactamase_B PF00753.27 KXH42087.1 - 2.1e-07 31.1 0.0 4.6e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KXH42087.1 - 1.4e-05 24.7 1.1 0.00049 19.7 1.1 2.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Pyr_redox_3 PF13738.6 KXH42088.1 - 6.3e-12 45.4 0.1 2.6e-08 33.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXH42088.1 - 6.3e-10 38.7 0.0 2.2e-08 33.7 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KXH42088.1 - 9.4e-10 37.5 0.0 3.5e-09 35.6 0.0 1.8 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KXH42088.1 - 2.8e-08 33.9 0.0 9.4e-07 29.0 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXH42088.1 - 6.2e-08 32.6 0.1 7e-05 22.6 0.0 3.8 4 0 0 4 4 4 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 KXH42088.1 - 2.8e-06 26.7 0.0 0.00053 19.2 0.0 2.3 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 KXH42088.1 - 7.5e-05 22.1 0.0 0.017 14.4 0.0 2.3 2 0 0 2 2 2 2 Thi4 family Pyr_redox PF00070.27 KXH42088.1 - 0.00025 21.5 0.0 1.9 9.1 0.0 3.3 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXH42088.1 - 0.0019 17.3 0.0 1.7 7.7 0.0 2.9 4 0 0 4 4 4 2 FAD binding domain Amino_oxidase PF01593.24 KXH42088.1 - 0.0033 16.8 0.0 0.0046 16.3 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 KXH42088.1 - 0.018 15.0 2.3 4.5 7.2 0.0 3.7 4 0 0 4 4 4 0 FAD-NAD(P)-binding Shikimate_DH PF01488.20 KXH42088.1 - 0.069 13.2 0.0 1.2 9.2 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase GIDA PF01134.22 KXH42088.1 - 0.19 10.8 0.1 14 4.6 0.0 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A CFEM PF05730.11 KXH42089.1 - 9.8e-14 51.2 8.8 1.7e-13 50.4 8.8 1.4 1 0 0 1 1 1 1 CFEM domain M_domain PF12938.7 KXH42089.1 - 0.91 9.3 6.2 1.3 8.8 6.2 1.1 1 0 0 1 1 1 0 M domain of GW182 Acyl-CoA_dh_M PF02770.19 KXH42090.1 - 9.8e-25 86.6 0.0 1.7e-24 85.9 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 KXH42090.1 - 7e-19 68.5 0.5 1.6e-15 57.6 0.5 2.3 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KXH42090.1 - 3.4e-11 43.8 0.2 1.8e-09 38.3 0.1 2.9 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain LPMO_10 PF03067.15 KXH42091.1 - 7.2e-09 36.6 0.2 1.3e-08 35.8 0.2 1.4 1 1 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading LANC_like PF05147.13 KXH42092.1 - 2.1e-21 75.9 0.0 6.3e-21 74.3 0.0 1.7 1 1 0 1 1 1 1 Lanthionine synthetase C-like protein RepA1_leader PF08048.12 KXH42093.1 - 0.59 10.4 2.7 1.5 9.1 2.7 1.7 1 0 0 1 1 1 0 Tap RepA1 leader peptide Glyco_hydro_61 PF03443.14 KXH42094.1 - 2.7e-59 200.6 0.4 3.4e-59 200.2 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.18 KXH42094.1 - 0.012 15.6 9.3 0.04 13.9 9.3 2.0 1 0 0 1 1 1 0 Fungal cellulose binding domain ADH_zinc_N PF00107.26 KXH42095.1 - 5.2e-10 39.4 0.0 8.6e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXH42095.1 - 7.3e-05 23.8 0.0 0.00011 23.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXH42095.1 - 0.00013 21.8 0.0 0.00023 21.0 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Fungal_trans PF04082.18 KXH42096.1 - 1.1e-11 44.3 0.2 3.6e-11 42.6 0.2 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_31 PF01055.26 KXH42097.1 - 2.3e-110 369.8 1.6 3.1e-110 369.4 1.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 DUF4968 PF16338.5 KXH42097.1 - 0.00018 21.7 0.0 0.00031 21.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4968) Gal_mutarotas_2 PF13802.6 KXH42097.1 - 0.00033 20.9 0.1 0.0018 18.6 0.1 2.3 1 1 0 1 1 1 1 Galactose mutarotase-like DUF2850 PF11012.8 KXH42097.1 - 0.11 12.8 0.6 0.49 10.7 0.1 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2850) zf-C2H2 PF00096.26 KXH42098.1 - 3.2e-09 36.7 9.5 0.00034 20.9 3.9 3.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 KXH42098.1 - 3.8e-09 36.3 7.5 0.00055 19.9 2.7 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KXH42098.1 - 2.7e-08 33.9 11.3 4.7e-07 29.9 3.8 3.2 3 0 0 3 3 3 2 Zinc-finger double domain Zn_clus PF00172.18 KXH42098.1 - 0.00012 22.1 11.8 0.00012 22.1 11.8 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_4 PF13894.6 KXH42098.1 - 0.00034 21.2 16.4 0.011 16.4 2.6 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger Fungal_trans PF04082.18 KXH42098.1 - 0.0041 16.2 0.1 0.0072 15.4 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2HE PF16278.5 KXH42098.1 - 0.78 10.2 4.2 18 5.9 4.2 2.4 1 1 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_jaz PF12171.8 KXH42098.1 - 1.6 9.1 13.4 0.75 10.2 0.6 3.6 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding Sugar_tr PF00083.24 KXH42099.1 - 2.1e-89 300.5 19.6 2.5e-89 300.2 19.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH42099.1 - 1.3e-20 73.7 30.1 1.3e-20 73.7 30.1 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KXH42099.1 - 5.2e-05 22.3 3.4 5.2e-05 22.3 3.4 1.6 2 0 0 2 2 2 1 MFS_1 like family Glyco_hydro_39 PF01229.17 KXH42100.1 - 3.6e-05 22.5 0.1 5.1e-05 22.1 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 39 FAD_binding_4 PF01565.23 KXH42101.1 - 4.7e-22 78.2 4.0 9e-22 77.3 4.0 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KXH42101.1 - 1.4e-11 44.3 0.4 3.5e-11 43.0 0.4 1.7 1 0 0 1 1 1 1 Berberine and berberine like RhodobacterPufX PF11511.8 KXH42102.1 - 0.23 11.1 3.9 0.69 9.6 3.9 1.8 1 0 0 1 1 1 0 Intrinsic membrane protein PufX HEPPP_synt_1 PF07307.11 KXH42103.1 - 0.064 12.8 0.1 0.14 11.7 0.1 1.5 1 0 0 1 1 1 0 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 tRNA-synt_1d PF00750.19 KXH42104.1 - 7.7e-63 212.5 0.0 1.1e-62 212.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 KXH42104.1 - 1.7e-13 50.8 0.1 3.4e-13 49.8 0.1 1.6 1 0 0 1 1 1 1 DALR anticodon binding domain Occludin_ELL PF07303.13 KXH42106.1 - 0.098 13.4 0.3 2.8 8.7 0.0 2.3 2 0 0 2 2 2 0 Occludin homology domain RPW8 PF05659.11 KXH42106.1 - 0.1 12.3 0.3 0.31 10.7 0.1 1.7 2 0 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 WXG100 PF06013.12 KXH42106.1 - 0.18 12.1 0.5 1 9.6 0.0 2.4 2 1 1 3 3 3 0 Proteins of 100 residues with WXG Spectrin PF00435.21 KXH42107.1 - 0.015 15.8 0.3 1.6 9.3 0.2 2.7 1 1 1 2 2 2 0 Spectrin repeat Laminin_II PF06009.12 KXH42107.1 - 0.049 13.6 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Laminin Domain II HeLo PF14479.6 KXH42107.1 - 0.065 13.1 1.6 0.65 9.8 0.0 2.4 2 1 0 3 3 3 0 Prion-inhibition and propagation Baculo_PEP_C PF04513.12 KXH42107.1 - 0.1 12.6 0.0 0.32 11.1 0.0 1.7 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Sipho_Gp157 PF05565.11 KXH42107.1 - 0.24 11.4 1.0 7.4 6.6 0.1 2.1 2 0 0 2 2 2 0 Siphovirus Gp157 CorA PF01544.18 KXH42107.1 - 2.2 7.5 6.9 0.77 9.0 0.4 2.3 3 0 0 3 3 3 0 CorA-like Mg2+ transporter protein Ribosomal_L37e PF01907.19 KXH42109.1 - 0.56 10.4 10.7 1.2 9.3 9.3 2.0 1 1 1 2 2 2 0 Ribosomal protein L37e RSN1_7TM PF02714.15 KXH42110.1 - 2e-84 283.2 12.6 2e-84 283.2 12.6 2.5 3 0 0 3 3 3 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KXH42110.1 - 3.7e-40 137.2 6.8 1.2e-39 135.5 6.8 2.0 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport PHM7_ext PF12621.8 KXH42110.1 - 2.2e-30 104.7 0.2 1.5e-28 98.8 0.1 2.4 2 0 0 2 2 2 1 Extracellular tail, of 10TM putative phosphate transporter PHM7_cyt PF14703.6 KXH42110.1 - 2.3e-27 96.3 0.0 3.5e-27 95.8 0.0 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RRM_1 PF00076.22 KXH42110.1 - 0.0085 15.9 0.0 0.02 14.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Transferase PF02458.15 KXH42111.1 - 1.6e-09 37.0 0.0 0.0012 17.6 0.0 2.9 3 0 0 3 3 3 3 Transferase family TauD PF02668.16 KXH42112.1 - 3.2e-55 187.8 0.5 3.7e-55 187.6 0.5 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family 2OG-FeII_Oxy_3 PF13640.6 KXH42112.1 - 0.0078 17.1 0.2 0.35 11.8 0.2 2.4 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily F-box-like PF12937.7 KXH42113.1 - 0.00078 19.3 0.5 0.016 15.1 0.0 3.1 4 0 0 4 4 4 1 F-box-like Fungal_trans PF04082.18 KXH42114.1 - 3.2e-38 131.3 0.0 6.7e-38 130.2 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Aminotran_5 PF00266.19 KXH42114.1 - 1.1e-30 106.9 0.0 3.6e-29 101.9 0.0 2.1 1 1 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 KXH42114.1 - 0.019 14.2 0.0 0.031 13.5 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II CorA PF01544.18 KXH42117.1 - 8e-11 41.8 0.1 2.3e-10 40.3 0.0 1.7 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein DUF5315 PF17242.2 KXH42117.1 - 0.12 12.2 0.1 0.24 11.2 0.1 1.5 1 0 0 1 1 1 0 Disordered region of unknown function (DUF5315) Cep57_CLD_2 PF14197.6 KXH42117.1 - 2.6 8.2 5.9 2.1 8.5 1.1 2.4 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 ASF1_hist_chap PF04729.13 KXH42118.1 - 8.2e-73 243.4 0.0 1.1e-72 243.0 0.0 1.2 1 0 0 1 1 1 1 ASF1 like histone chaperone DMSP_lyase PF16867.5 KXH42118.1 - 0.18 11.5 0.0 0.3 10.7 0.0 1.3 1 0 0 1 1 1 0 Dimethlysulfonioproprionate lyase Suf PF05843.14 KXH42119.1 - 6e-77 259.5 0.0 6e-77 259.5 0.0 4.4 4 2 1 5 5 5 1 Suppressor of forked protein (Suf) TPR_14 PF13428.6 KXH42119.1 - 1.1e-06 28.9 4.0 0.0073 17.0 5.8 4.5 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 KXH42119.1 - 0.00024 21.7 0.3 0.014 16.0 1.3 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 KXH42119.1 - 0.0011 19.5 0.0 0.017 15.7 0.2 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 KXH42119.1 - 0.011 15.9 1.2 0.027 14.6 1.2 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat Peptidase_S80 PF07230.11 KXH42119.1 - 0.037 12.3 0.0 0.058 11.7 0.0 1.1 1 0 0 1 1 1 0 Bacteriophage T4-like capsid assembly protein (Gp20) TPR_17 PF13431.6 KXH42119.1 - 0.056 13.8 0.0 7.8 7.1 0.1 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat HrpJ PF07201.11 KXH42119.1 - 2.6 8.3 9.9 2.7 8.3 0.6 3.8 4 0 0 4 4 4 0 HrpJ-like domain Piwi PF02171.17 KXH42120.1 - 1.2e-77 261.1 0.0 1.9e-77 260.5 0.0 1.3 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 KXH42120.1 - 1.8e-20 74.0 0.0 4.1e-20 72.8 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 KXH42120.1 - 1.4e-15 56.6 1.2 6.7e-15 54.5 0.1 2.6 3 0 0 3 3 3 1 Argonaute linker 1 domain PAZ PF02170.22 KXH42120.1 - 1.7e-11 44.1 0.1 3.3e-11 43.2 0.1 1.4 1 0 0 1 1 1 1 PAZ domain ArgoL2 PF16488.5 KXH42120.1 - 1.8e-09 37.8 0.0 6.1e-09 36.1 0.0 2.0 1 0 0 1 1 1 1 Argonaute linker 2 domain ArgoMid PF16487.5 KXH42120.1 - 3.6e-08 33.5 0.0 1.3e-07 31.8 0.0 2.0 1 0 0 1 1 1 1 Mid domain of argonaute NTP_transferase PF00483.23 KXH42121.1 - 3.5e-05 23.5 0.0 5.4e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 KXH42121.1 - 0.007 16.7 0.0 0.013 15.8 0.0 1.5 1 0 0 1 1 1 1 MobA-like NTP transferase domain APH PF01636.23 KXH42121.1 - 0.0086 16.0 0.0 0.019 14.9 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Nuc_sug_transp PF04142.15 KXH42122.1 - 1.4e-28 100.0 18.8 1.3e-24 87.0 17.9 2.3 2 0 0 2 2 2 2 Nucleotide-sugar transporter PsbH PF00737.20 KXH42122.1 - 0.0096 15.6 0.1 0.031 14.0 0.1 1.9 1 0 0 1 1 1 1 Photosystem II 10 kDa phosphoprotein Glyco_hydro_32N PF00251.20 KXH42123.1 - 1.8e-60 205.1 4.6 2.7e-60 204.5 4.6 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 KXH42123.1 - 1.2e-09 38.3 0.1 2.1e-09 37.6 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal BNR PF02012.20 KXH42123.1 - 0.22 11.7 2.1 11 6.6 0.2 3.4 2 0 0 2 2 2 0 BNR/Asp-box repeat zf-C2H2 PF00096.26 KXH42124.1 - 2.6e-12 46.5 17.9 6.9e-06 26.2 0.8 3.6 3 1 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXH42124.1 - 2.9e-06 27.6 14.6 0.011 16.5 0.3 3.7 3 1 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KXH42124.1 - 7.8e-06 26.1 9.1 0.016 15.6 0.3 4.4 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KXH42124.1 - 4.1e-05 23.8 2.4 0.054 13.8 1.1 3.3 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KXH42124.1 - 8.5e-05 22.4 2.7 0.011 15.7 0.3 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger FOXP-CC PF16159.5 KXH42124.1 - 0.00057 20.5 6.4 0.25 12.0 0.2 3.1 1 1 2 3 3 3 2 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 KXH42124.1 - 0.012 15.9 0.5 0.16 12.3 0.2 2.3 1 1 1 2 2 2 0 C2H2-type zinc ribbon COE1_DBD PF16422.5 KXH42124.1 - 0.028 13.9 0.3 0.045 13.2 0.3 1.3 1 0 0 1 1 1 0 Transcription factor COE1 DNA-binding domain zf_ZIC PF18366.1 KXH42124.1 - 0.21 11.7 4.3 3.7 7.7 0.2 3.1 3 0 0 3 3 3 0 Zic proteins zinc finger domain OrsD PF12013.8 KXH42124.1 - 0.48 10.9 4.8 23 5.5 0.0 3.0 2 1 1 3 3 3 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf-H2C2_5 PF13909.6 KXH42124.1 - 0.61 9.9 8.5 2.1 8.2 0.4 3.4 3 0 0 3 3 3 0 C2H2-type zinc-finger domain Sugar_tr PF00083.24 KXH42125.1 - 2.2e-44 152.1 19.6 5.9e-44 150.7 19.6 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH42125.1 - 6.4e-15 54.9 29.0 1.1e-14 54.1 28.3 1.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Lgl_C PF08596.10 KXH42126.1 - 2.4e-111 372.2 0.0 5.3e-111 371.1 0.0 1.6 2 0 0 2 2 2 1 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.32 KXH42126.1 - 1.9e-05 25.3 1.0 0.017 16.0 0.0 4.4 4 0 0 4 4 4 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXH42126.1 - 6.1e-05 23.2 0.0 0.23 11.8 0.0 4.3 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain DUF1338 PF07063.13 KXH42128.1 - 5.2e-109 364.4 0.2 6.4e-109 364.1 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1338) PALP PF00291.25 KXH42129.1 - 1.7e-57 195.1 0.0 2.2e-57 194.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Fungal_trans PF04082.18 KXH42130.1 - 3.2e-22 78.8 0.0 6.6e-22 77.8 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Lipase_GDSL_2 PF13472.6 KXH42130.1 - 3.5e-15 56.8 0.0 7.2e-15 55.8 0.0 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KXH42130.1 - 2.8e-07 30.7 0.0 3.8e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 KXH42130.1 - 0.00013 22.2 0.0 0.00031 20.9 0.0 1.6 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Aminotran_4 PF01063.19 KXH42131.1 - 9.3e-25 87.8 0.0 1.1e-24 87.5 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV Abhydrolase_1 PF00561.20 KXH42133.1 - 9.7e-15 54.9 0.4 6e-14 52.3 0.4 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXH42133.1 - 5.4e-07 30.4 0.5 7.4e-07 30.0 0.5 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXH42133.1 - 1.7e-05 24.2 0.0 0.014 14.6 0.1 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Choline_kinase PF01633.20 KXH42173.1 - 2e-52 177.9 0.0 1.5e-51 175.0 0.0 2.0 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.23 KXH42173.1 - 7e-12 45.8 0.0 1.9e-11 44.3 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.20 KXH42173.1 - 0.0011 18.4 0.0 0.0018 17.7 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase DUF2451 PF10474.9 KXH42173.1 - 0.09 12.6 0.1 3 7.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function C-terminus (DUF2451) NPR3 PF03666.13 KXH42174.1 - 1.1e-144 482.8 0.3 1.5e-144 482.3 0.3 1.2 1 0 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 DUF913 PF06025.12 KXH42174.1 - 0.12 11.3 0.8 0.25 10.3 0.8 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) ATHILA PF03078.15 KXH42174.1 - 1.4 7.7 7.4 2.6 6.8 7.4 1.3 1 0 0 1 1 1 0 ATHILA ORF-1 family ERp29 PF07749.12 KXH42174.1 - 1.7 9.6 6.3 1.3 10.0 0.3 2.7 2 0 0 2 2 2 0 Endoplasmic reticulum protein ERp29, C-terminal domain HLH PF00010.26 KXH42175.1 - 2e-12 46.8 0.0 8.4e-12 44.9 0.0 2.0 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF1722 PF08349.11 KXH42175.1 - 0.15 12.3 0.0 0.38 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1722) FYVE_2 PF02318.16 KXH42176.1 - 0.099 12.9 0.1 0.19 11.9 0.1 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger Got1 PF04178.12 KXH42177.1 - 7.7e-35 119.7 15.7 1.1e-34 119.2 15.7 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family La PF05383.17 KXH42178.1 - 1e-16 60.7 0.0 2e-16 59.8 0.0 1.5 1 0 0 1 1 1 1 La domain COesterase PF00135.28 KXH42185.1 - 2.9e-67 227.7 0.0 3.8e-67 227.3 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXH42185.1 - 6e-07 29.5 0.8 5.8e-06 26.3 0.8 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 KXH42185.1 - 0.00066 19.4 0.3 0.016 14.9 0.0 2.6 2 1 0 2 2 2 1 Putative esterase Peptidase_S9 PF00326.21 KXH42185.1 - 0.0022 17.5 0.4 0.0044 16.5 0.4 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Say1_Mug180 PF10340.9 KXH42185.1 - 0.022 13.7 0.0 0.76 8.6 0.0 2.0 2 0 0 2 2 2 0 Steryl acetyl hydrolase AXE1 PF05448.12 KXH42185.1 - 0.12 11.0 0.0 0.23 10.1 0.0 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Chlorophyllase2 PF12740.7 KXH42185.1 - 0.18 10.7 0.0 0.38 9.6 0.0 1.5 1 0 0 1 1 1 0 Chlorophyllase enzyme DegT_DnrJ_EryC1 PF01041.17 KXH42186.1 - 5.7e-88 295.6 0.0 6.8e-88 295.4 0.0 1.0 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 KXH42186.1 - 3.4e-08 33.0 0.0 4.6e-07 29.3 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KXH42186.1 - 4.6e-07 29.1 0.0 5.5e-07 28.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V OKR_DC_1 PF01276.20 KXH42186.1 - 7.3e-07 28.3 0.0 1.1e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain Cys_Met_Meta_PP PF01053.20 KXH42186.1 - 1.9e-06 26.7 0.2 2.9e-06 26.1 0.2 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 KXH42186.1 - 0.0024 17.2 0.1 0.0056 16.0 0.1 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase His_Phos_2 PF00328.22 KXH42187.1 - 1.4e-11 44.3 0.0 2.2e-06 27.3 0.0 2.2 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) Hexapep PF00132.24 KXH42188.1 - 1.2e-14 53.4 8.3 2.2e-10 39.8 3.8 3.3 3 0 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KXH42188.1 - 6.7e-14 51.3 8.6 6.6e-11 41.8 2.9 3.1 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Mac PF12464.8 KXH42188.1 - 4.4e-10 39.6 0.1 7.1e-10 39.0 0.1 1.3 1 0 0 1 1 1 1 Maltose acetyltransferase MFS_1 PF07690.16 KXH42189.1 - 2.2e-16 59.7 51.8 1.5e-09 37.2 20.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily GDP_Man_Dehyd PF16363.5 KXH42190.1 - 1.4e-47 162.8 0.0 1.7e-47 162.4 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KXH42190.1 - 9e-40 136.6 0.0 1.2e-39 136.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXH42190.1 - 2.4e-10 39.9 0.0 3.2e-10 39.5 0.0 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KXH42190.1 - 1.2e-06 27.9 0.0 0.0081 15.4 0.0 2.4 2 1 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 KXH42190.1 - 0.0035 17.3 0.0 0.0062 16.4 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 KXH42190.1 - 0.0078 15.7 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase UPF0146 PF03686.13 KXH42190.1 - 0.019 14.8 0.0 0.18 11.7 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0146) RmlD_sub_bind PF04321.17 KXH42190.1 - 0.021 14.0 0.0 0.041 13.0 0.0 1.5 1 1 0 1 1 1 0 RmlD substrate binding domain KR PF08659.10 KXH42190.1 - 0.057 13.3 0.1 0.11 12.4 0.1 1.4 1 0 0 1 1 1 0 KR domain NmrA PF05368.13 KXH42190.1 - 0.062 12.8 0.0 0.09 12.3 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family UDPG_MGDP_dh_N PF03721.14 KXH42191.1 - 5.7e-46 156.4 0.0 8.4e-46 155.9 0.0 1.2 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.19 KXH42191.1 - 2.2e-27 95.1 0.0 4.5e-27 94.1 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.15 KXH42191.1 - 3.5e-21 75.6 0.0 4.9e-20 71.9 0.0 2.7 2 1 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain ApbA PF02558.16 KXH42191.1 - 0.028 14.1 0.0 0.081 12.6 0.0 1.8 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 KXH42191.1 - 0.13 12.1 0.0 0.36 10.7 0.0 1.8 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 4HB_MCP_1 PF12729.7 KXH42193.1 - 0.0048 16.5 0.8 0.0082 15.7 0.2 1.8 2 0 0 2 2 2 1 Four helix bundle sensory module for signal transduction SesA PF17107.5 KXH42193.1 - 0.019 15.1 0.1 0.039 14.2 0.1 1.4 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases PTCB-BRCT PF12738.7 KXH42194.1 - 1.6e-45 152.9 0.1 1.8e-20 72.7 0.0 4.4 4 0 0 4 4 4 3 twin BRCT domain BRCT PF00533.26 KXH42194.1 - 1.6e-37 127.7 0.1 1.4e-11 44.6 0.0 4.7 4 1 0 4 4 4 4 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KXH42194.1 - 1.1e-18 67.4 0.1 0.00022 21.5 0.0 4.7 4 0 0 4 4 4 4 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 KXH42194.1 - 3.4e-07 30.4 0.2 0.27 11.5 0.0 3.7 3 0 0 3 3 3 2 DNA ligase 3 BRCT domain BRCT_3 PF18428.1 KXH42194.1 - 8.9e-05 22.5 0.2 0.11 12.6 0.0 3.6 4 0 0 4 4 4 1 BRCA1 C Terminus (BRCT) domain GAS PF13851.6 KXH42198.1 - 0.003 17.0 0.9 0.0043 16.4 0.9 1.1 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding TMCO5 PF14992.6 KXH42198.1 - 0.087 12.4 3.5 0.13 11.8 3.5 1.2 1 0 0 1 1 1 0 TMCO5 family RNA_pol_Rpb2_6 PF00562.28 KXH42199.1 - 4e-121 404.7 0.0 6.3e-121 404.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 KXH42199.1 - 2.4e-54 184.0 0.2 4.1e-54 183.2 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 KXH42199.1 - 1.1e-33 115.4 0.5 2.8e-33 114.2 0.5 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 KXH42199.1 - 1.9e-30 105.9 0.1 4.1e-30 104.8 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.13 KXH42199.1 - 3.1e-22 78.6 0.2 7.7e-22 77.3 0.2 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 KXH42199.1 - 2.4e-19 69.3 0.0 4.8e-19 68.3 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 KXH42199.1 - 3.2e-10 40.4 2.4 1.1e-09 38.6 2.4 2.0 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 5 MMU163 PF17119.5 KXH42200.1 - 7.8e-71 238.1 4.7 3.2e-52 177.1 0.7 2.2 1 1 1 2 2 2 2 Mitochondrial protein up-regulated during meiosis Tom5 PF10642.9 KXH42200.1 - 0.44 10.6 0.1 0.44 10.6 0.1 2.0 2 0 0 2 2 2 0 Mitochondrial import receptor subunit or translocase MFS_1 PF07690.16 KXH42202.1 - 5.5e-35 120.9 50.9 7.5e-29 100.8 15.2 2.7 2 1 0 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.13 KXH42202.1 - 1.5e-08 33.6 11.7 2.9e-08 32.6 11.7 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.6 KXH42202.1 - 0.00034 19.3 2.7 0.00034 19.3 2.7 2.9 3 1 0 3 3 3 2 MFS/sugar transport protein DUF4552 PF15089.6 KXH42203.1 - 0.19 10.7 0.0 0.25 10.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4552) Carn_acyltransf PF00755.20 KXH42205.1 - 5.3e-209 695.7 0.0 4e-208 692.8 0.0 1.9 1 1 0 1 1 1 1 Choline/Carnitine o-acyltransferase AnfO_nitrog PF09582.10 KXH42205.1 - 0.042 13.2 0.0 0.079 12.3 0.0 1.3 1 0 0 1 1 1 0 Iron only nitrogenase protein AnfO (AnfO_nitrog) TrbC PF04956.13 KXH42206.1 - 0.058 13.6 0.1 0.12 12.6 0.1 1.5 1 0 0 1 1 1 0 TrbC/VIRB2 family Podoplanin PF05808.11 KXH42206.1 - 0.088 12.9 1.2 0.11 12.6 0.1 1.7 2 0 0 2 2 2 0 Podoplanin Rad51 PF08423.11 KXH42208.1 - 2.1e-40 138.6 0.0 1.6e-39 135.8 0.0 1.9 1 1 0 1 1 1 1 Rad51 AAA_25 PF13481.6 KXH42208.1 - 4.2e-07 29.7 0.0 1e-06 28.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain ATPase PF06745.13 KXH42208.1 - 4.9e-06 26.1 0.0 1e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 KaiC RecA PF00154.21 KXH42208.1 - 5.3e-06 26.1 0.0 0.00027 20.5 0.0 2.1 2 0 0 2 2 2 1 recA bacterial DNA recombination protein AAA_22 PF13401.6 KXH42208.1 - 0.091 13.0 0.0 0.36 11.1 0.0 2.1 2 1 0 2 2 2 0 AAA domain Pox_A32 PF04665.12 KXH42208.1 - 0.099 12.1 0.1 0.17 11.3 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_24 PF13479.6 KXH42208.1 - 0.12 12.1 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KXH42208.1 - 0.19 12.2 0.1 0.35 11.4 0.1 1.4 1 0 0 1 1 1 0 ABC transporter Ras PF00071.22 KXH42209.1 - 4.3e-18 65.4 0.5 5.7e-17 61.8 0.5 2.0 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KXH42209.1 - 0.0044 17.2 0.1 0.0084 16.3 0.1 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SAS4 PF15460.6 KXH42210.1 - 0.027 14.5 1.2 0.99 9.5 0.3 2.4 2 0 0 2 2 2 0 Something about silencing, SAS, complex subunit 4 DUF883 PF05957.13 KXH42210.1 - 0.36 11.5 1.2 4.2 8.0 0.0 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) WD40 PF00400.32 KXH42212.1 - 2.6e-12 47.0 12.3 0.016 16.1 0.1 6.4 6 1 0 6 6 6 3 WD domain, G-beta repeat PQQ_3 PF13570.6 KXH42212.1 - 0.023 15.2 1.1 1.2 9.7 0.1 3.8 5 0 0 5 5 5 0 PQQ-like domain Sigma70_r1_2 PF00140.20 KXH42212.1 - 0.057 13.4 0.7 0.057 13.4 0.7 2.3 3 0 0 3 3 3 0 Sigma-70 factor, region 1.2 Mcl1_mid PF12341.8 KXH42213.1 - 2.8e-100 335.5 0.0 1.5e-98 329.9 0.0 2.5 3 0 0 3 3 3 1 Minichromosome loss protein, Mcl1, middle region WD40 PF00400.32 KXH42213.1 - 1.4e-21 76.4 0.6 4.2e-08 33.7 0.0 7.1 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXH42213.1 - 3.7e-19 68.8 0.0 9.6e-05 22.6 0.1 7.5 2 1 6 8 8 8 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KXH42213.1 - 3.7e-05 23.7 0.1 0.00033 20.6 0.2 2.2 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.14 KXH42213.1 - 5.6e-05 22.4 0.0 0.00042 19.5 0.0 1.9 1 1 1 2 2 2 1 Coatomer WD associated region Ge1_WD40 PF16529.5 KXH42213.1 - 0.0034 16.4 0.1 3 6.7 0.0 2.9 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein MMS1_N PF10433.9 KXH42213.1 - 0.049 12.3 0.0 2.4 6.7 0.0 2.4 1 1 0 2 2 2 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term SH3_15 PF18346.1 KXH42213.1 - 0.078 13.3 0.1 0.81 10.0 0.0 2.4 2 0 0 2 2 2 0 Mind bomb SH3 repeat domain KTSC PF13619.6 KXH42213.1 - 0.09 12.6 0.0 4.4 7.2 0.0 2.6 2 0 0 2 2 2 0 KTSC domain WD40_3 PF15911.5 KXH42213.1 - 0.095 12.7 0.0 2 8.5 0.0 2.9 3 0 0 3 3 3 0 WD domain, G-beta repeat PQQ_3 PF13570.6 KXH42213.1 - 0.56 10.8 4.9 19 5.9 0.0 4.9 5 1 0 5 5 5 0 PQQ-like domain Ras PF00071.22 KXH42319.1 - 5.1e-38 130.2 0.1 6.3e-38 129.9 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXH42319.1 - 1.2e-17 64.3 0.0 1.8e-17 63.6 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXH42319.1 - 4e-09 36.1 0.1 5.1e-09 35.8 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KXH42319.1 - 3.3e-05 23.5 0.0 4.1e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KXH42319.1 - 0.00068 19.1 0.0 0.00082 18.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PMT PF02366.18 KXH42320.1 - 4.6e-84 281.8 12.0 4.6e-84 281.8 12.0 2.2 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 KXH42320.1 - 1.9e-66 223.5 14.4 1.9e-66 223.5 14.4 2.0 2 1 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 KXH42320.1 - 6.7e-37 127.1 0.3 1.1e-36 126.5 0.3 1.2 1 0 0 1 1 1 1 MIR domain zinc_ribbon_6 PF14599.6 KXH42321.1 - 1.5e-24 85.8 0.0 1.5e-24 85.8 0.0 4.1 3 1 1 4 4 4 1 Zinc-ribbon zf-CHY PF05495.12 KXH42321.1 - 5.9e-21 74.7 20.7 5.9e-21 74.7 20.7 3.6 3 1 0 3 3 3 1 CHY zinc finger zf-RING_2 PF13639.6 KXH42321.1 - 4.6e-08 33.3 6.8 4.6e-08 33.3 6.8 5.3 2 2 4 6 6 6 1 Ring finger domain zf-RING_UBOX PF13445.6 KXH42321.1 - 2.9e-06 27.2 2.8 2.9e-06 27.2 2.8 3.9 5 1 0 5 5 5 1 RING-type zinc-finger zf-RING_5 PF14634.6 KXH42321.1 - 5.1e-06 26.3 6.5 5.1e-06 26.3 6.5 6.7 3 2 1 4 4 4 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KXH42321.1 - 6.6e-05 22.7 7.4 6.6e-05 22.7 7.4 4.9 3 2 3 6 6 6 1 Zinc finger, C3HC4 type (RING finger) RNA_pol_3_Rpc31 PF11705.8 KXH42321.1 - 0.0013 19.0 0.1 0.0021 18.3 0.1 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 Cwf_Cwc_15 PF04889.12 KXH42321.1 - 1.6 8.4 6.3 3.2 7.4 6.3 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein MOZART1 PF12554.8 KXH42322.1 - 3.6e-26 90.7 0.7 4.4e-26 90.4 0.7 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated Rrn6 PF10214.9 KXH42323.1 - 1.1e-198 662.7 0.8 2e-198 661.9 0.8 1.4 1 1 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor DUF4081 PF13312.6 KXH42323.1 - 0.13 12.5 0.3 0.76 10.0 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4081) PITH PF06201.13 KXH42324.1 - 2.4e-45 154.5 0.0 2.9e-45 154.2 0.0 1.1 1 0 0 1 1 1 1 PITH domain Acetyltransf_1 PF00583.25 KXH42325.1 - 8.8e-09 35.6 0.0 1.3e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXH42325.1 - 2.4e-08 34.0 0.0 3.5e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXH42325.1 - 2.5e-08 34.2 0.0 3.8e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KXH42325.1 - 0.0023 18.0 0.1 0.039 14.0 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXH42325.1 - 0.084 12.9 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Sugar_tr PF00083.24 KXH42327.1 - 6.9e-103 344.9 17.9 8.4e-103 344.6 17.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH42327.1 - 8.4e-26 90.7 52.2 1.2e-24 87.0 26.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KXH42327.1 - 1.1e-07 30.7 21.6 2.9e-05 22.8 6.2 2.8 3 0 0 3 3 3 2 MFS/sugar transport protein MFS_1_like PF12832.7 KXH42327.1 - 0.008 15.1 7.6 0.062 12.1 0.1 2.5 2 1 0 2 2 2 2 MFS_1 like family DUF2530 PF10745.9 KXH42327.1 - 0.4 10.9 3.7 1.9 8.8 0.4 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) MFS_3 PF05977.13 KXH42327.1 - 0.92 7.8 5.4 1.4 7.2 0.5 2.1 2 0 0 2 2 2 0 Transmembrane secretion effector Fungal_trans_2 PF11951.8 KXH42328.1 - 1.2e-26 93.5 0.0 1.4e-26 93.3 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Amino_oxidase PF01593.24 KXH42329.1 - 8.3e-43 147.3 2.6 1.5e-41 143.2 2.6 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KXH42329.1 - 1.5e-09 37.9 1.0 4.3e-09 36.5 0.4 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXH42329.1 - 1.2e-07 31.6 0.5 1.9e-05 24.5 0.6 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXH42329.1 - 4.5e-07 29.4 0.1 2.1e-05 23.9 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXH42329.1 - 2.7e-06 26.8 0.0 4.9e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 KXH42329.1 - 5.4e-06 26.0 0.8 5.6e-05 22.7 0.2 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KXH42329.1 - 2.8e-05 23.4 0.5 6.3e-05 22.2 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 KXH42329.1 - 0.00021 20.5 0.3 0.0024 17.0 0.1 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein HI0933_like PF03486.14 KXH42329.1 - 0.00033 19.5 0.0 0.00061 18.6 0.0 1.4 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 KXH42329.1 - 0.0034 17.9 0.4 0.064 13.8 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXH42329.1 - 0.0084 16.1 0.9 0.19 11.7 0.1 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 KXH42329.1 - 0.0086 15.4 0.5 0.042 13.1 0.2 2.0 1 1 1 2 2 2 1 FAD binding domain GIDA PF01134.22 KXH42329.1 - 0.016 14.4 0.2 0.07 12.2 0.0 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A Mito_carr PF00153.27 KXH42330.1 - 7e-31 106.0 0.7 1.3e-15 57.0 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein RNA_pol_Rpc82 PF05645.13 KXH42331.1 - 1.9e-47 162.2 0.0 7e-46 157.1 0.0 2.7 2 1 0 3 3 3 1 RNA polymerase III subunit RPC82 HTH_9 PF08221.11 KXH42331.1 - 3.2e-14 52.7 0.5 1.8e-12 47.2 0.2 2.8 2 0 0 2 2 2 1 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.17 KXH42331.1 - 3.2e-06 27.0 0.0 0.0079 16.0 0.0 3.4 3 1 1 4 4 4 2 TFIIE alpha subunit Peptidase_M16 PF00675.20 KXH42332.1 - 5.9e-16 58.8 0.1 1.2e-15 57.8 0.1 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KXH42332.1 - 2.2e-10 40.8 0.0 3.9e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase M16 inactive domain LsmAD PF06741.13 KXH42333.1 - 2.5e-28 98.4 1.5 2.5e-28 98.4 1.5 2.3 2 0 0 2 2 2 1 LsmAD domain Tantalus PF15386.6 KXH42333.1 - 0.059 13.5 0.0 0.17 12.0 0.0 1.8 1 0 0 1 1 1 0 Drosophila Tantalus-like Glyco_hydro_61 PF03443.14 KXH42334.1 - 0.071 13.0 0.8 0.18 11.7 0.1 2.2 2 1 0 2 2 2 0 Glycosyl hydrolase family 61 BSD PF03909.17 KXH42335.1 - 7.1e-30 102.8 0.8 1.3e-13 50.7 0.1 2.9 2 0 0 2 2 2 2 BSD domain PH_TFIIH PF08567.11 KXH42335.1 - 3.5e-26 91.3 0.2 1.1e-25 89.8 0.0 1.9 2 0 0 2 2 2 1 TFIIH p62 subunit, N-terminal domain AAA PF00004.29 KXH42336.1 - 2e-38 131.8 0.2 3.1e-37 128.0 0.0 2.8 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KXH42336.1 - 4.1e-08 32.9 0.3 1.1e-07 31.5 0.3 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KXH42336.1 - 2.6e-06 27.9 0.3 0.0018 18.7 0.0 3.2 2 1 0 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 KXH42336.1 - 1.3e-05 25.0 0.0 2.9e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KXH42336.1 - 0.00023 21.5 0.5 0.094 13.0 0.1 3.1 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.17 KXH42336.1 - 0.00064 19.5 0.0 0.0017 18.1 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.6 KXH42336.1 - 0.0018 18.3 0.0 0.0095 16.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KXH42336.1 - 0.002 18.3 0.2 0.016 15.4 0.2 2.5 1 1 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 KXH42336.1 - 0.01 15.8 0.1 5 7.0 0.0 2.7 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea AAA_7 PF12775.7 KXH42336.1 - 0.011 15.2 0.0 1.4 8.4 0.0 2.6 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_5 PF07728.14 KXH42336.1 - 0.015 15.3 0.1 0.039 14.0 0.1 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) TniB PF05621.11 KXH42336.1 - 0.016 14.7 0.0 0.83 9.0 0.0 2.4 1 1 1 2 2 2 0 Bacterial TniB protein AAA_18 PF13238.6 KXH42336.1 - 0.021 15.4 0.0 0.064 13.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KXH42336.1 - 0.022 15.0 0.2 0.7 10.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KXH42336.1 - 0.025 14.9 0.0 0.087 13.2 0.0 1.9 1 0 0 1 1 1 0 RNA helicase Hydin_ADK PF17213.3 KXH42336.1 - 0.035 14.4 0.4 5.5 7.2 0.0 3.2 3 0 0 3 3 3 0 Hydin Adenylate kinase-like domain Mg_chelatase PF01078.21 KXH42336.1 - 0.041 13.3 0.0 0.093 12.1 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 KXH42336.1 - 0.046 13.4 0.0 0.097 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 KXH42336.1 - 0.06 12.5 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain NACHT PF05729.12 KXH42336.1 - 0.13 12.2 0.3 3.1 7.7 0.1 2.7 2 0 0 2 2 2 0 NACHT domain ABC_tran PF00005.27 KXH42336.1 - 0.14 12.7 0.0 1 9.9 0.0 2.4 3 0 0 3 3 2 0 ABC transporter AAA_25 PF13481.6 KXH42336.1 - 0.14 11.7 0.3 2.2 7.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain Mus7 PF09462.10 KXH42337.1 - 8e-131 437.9 1.9 1.1e-130 437.5 1.9 1.2 1 0 0 1 1 1 1 Mus7/MMS22 family Activator-TraM PF11657.8 KXH42337.1 - 0.15 11.9 2.3 0.27 11.1 0.3 2.3 2 0 0 2 2 2 0 Transcriptional activator TraM COX4 PF02936.14 KXH42338.1 - 2e-48 163.9 0.1 2.3e-48 163.7 0.1 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV Alpha-amylase_C PF02806.18 KXH42339.1 - 2.2e-26 92.2 0.1 7.8e-26 90.4 0.1 2.0 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain CBM_48 PF02922.18 KXH42339.1 - 2e-18 66.5 0.0 6.6e-18 64.9 0.0 2.0 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 KXH42339.1 - 3.2e-15 56.5 0.1 1.8e-11 44.2 0.1 2.4 1 1 1 2 2 2 2 Alpha amylase, catalytic domain AMPK1_CBM PF16561.5 KXH42339.1 - 0.018 15.2 0.0 0.05 13.8 0.0 1.7 1 0 0 1 1 1 0 Glycogen recognition site of AMP-activated protein kinase AAA_2 PF07724.14 KXH42340.1 - 1.7e-31 109.6 0.0 3.9e-31 108.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 KXH42340.1 - 2.8e-12 47.2 0.0 5.3e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 KXH42340.1 - 5.5e-09 36.0 0.0 1.2e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 KXH42340.1 - 4e-08 33.3 0.0 8.8e-08 32.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KXH42340.1 - 5.2e-05 23.5 0.3 0.0016 18.7 0.3 2.6 1 1 0 1 1 1 1 AAA domain MCM PF00493.23 KXH42340.1 - 0.00017 20.8 0.0 0.00035 19.7 0.0 1.4 1 0 0 1 1 1 1 MCM P-loop domain AAA_14 PF13173.6 KXH42340.1 - 0.0048 16.9 0.0 0.009 16.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KXH42340.1 - 0.0054 17.1 0.1 0.029 14.8 0.0 2.0 1 1 1 2 2 2 1 AAA ATPase domain AAA_7 PF12775.7 KXH42340.1 - 0.0065 16.0 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region IstB_IS21 PF01695.17 KXH42340.1 - 0.019 14.7 0.0 0.036 13.8 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.6 KXH42340.1 - 0.026 15.1 0.0 0.026 15.1 0.0 1.9 2 0 0 2 2 1 0 AAA domain TniB PF05621.11 KXH42340.1 - 0.065 12.6 0.0 0.46 9.9 0.0 2.1 2 0 0 2 2 2 0 Bacterial TniB protein ABC_tran PF00005.27 KXH42340.1 - 0.11 13.1 0.1 0.22 12.0 0.1 1.5 1 0 0 1 1 1 0 ABC transporter Rad17 PF03215.15 KXH42340.1 - 0.12 12.3 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_24 PF13479.6 KXH42340.1 - 0.13 12.0 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 KXH42340.1 - 0.2 10.7 0.1 0.33 10.0 0.1 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_19 PF13245.6 KXH42340.1 - 0.68 10.3 1.9 0.81 10.0 0.1 2.0 2 1 1 3 3 3 0 AAA domain ATP-synt_ab PF00006.25 KXH42341.1 - 7.2e-62 208.8 0.0 1.1e-61 208.2 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 KXH42341.1 - 8.7e-24 83.8 0.2 2.4e-23 82.4 0.2 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain AAA PF00004.29 KXH42341.1 - 0.0087 16.5 0.1 0.52 10.7 0.0 2.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 KXH42341.1 - 0.01 15.7 0.5 0.027 14.4 0.1 1.9 2 0 0 2 2 2 0 RsgA GTPase NB-ARC PF00931.22 KXH42341.1 - 0.015 14.5 0.4 0.082 12.1 0.1 2.0 2 0 0 2 2 2 0 NB-ARC domain ATPase_2 PF01637.18 KXH42341.1 - 0.031 14.2 0.0 0.079 12.9 0.0 1.6 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea ATPase PF06745.13 KXH42341.1 - 0.037 13.4 0.2 0.065 12.6 0.2 1.4 1 0 0 1 1 1 0 KaiC NACHT PF05729.12 KXH42341.1 - 0.053 13.5 0.1 0.13 12.2 0.0 1.6 2 0 0 2 2 2 0 NACHT domain T3SS_ATPase_C PF18269.1 KXH42341.1 - 0.06 13.2 0.7 0.32 10.9 0.7 2.1 1 1 0 1 1 1 0 T3SS EscN ATPase C-terminal domain AAA_19 PF13245.6 KXH42341.1 - 0.065 13.6 2.0 0.48 10.8 0.2 2.4 3 0 0 3 3 2 0 AAA domain RNA_helicase PF00910.22 KXH42341.1 - 0.078 13.4 0.0 0.17 12.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_16 PF13191.6 KXH42341.1 - 0.12 12.7 0.3 0.4 11.0 0.1 2.0 2 1 0 2 2 2 0 AAA ATPase domain DUF4050 PF13259.6 KXH42342.1 - 3.3e-62 210.1 0.1 3.3e-62 210.1 0.1 2.7 2 1 0 2 2 2 1 Protein of unknown function (DUF4050) PAPA-1 PF04795.12 KXH42343.1 - 3.6e-25 88.6 0.7 3.6e-25 88.6 0.7 4.2 4 1 1 5 5 5 1 PAPA-1-like conserved region NOA36 PF06524.12 KXH42343.1 - 1.1 8.5 40.9 1.3 8.2 21.4 2.4 2 0 0 2 2 2 0 NOA36 protein Pex14_N PF04695.13 KXH42344.1 - 5.6e-41 140.8 6.1 5.6e-41 140.8 6.1 2.4 2 0 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Ribosomal_60s PF00428.19 KXH42344.1 - 0.091 13.4 5.6 0.46 11.1 2.8 2.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein Chromo PF00385.24 KXH42345.1 - 2.3e-08 33.8 0.4 8e-08 32.1 0.4 2.0 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Ras PF00071.22 KXH42346.1 - 2.7e-63 212.4 0.2 3.2e-63 212.2 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXH42346.1 - 2.8e-35 121.1 0.2 3.9e-35 120.7 0.2 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXH42346.1 - 4.7e-13 49.0 0.1 6e-13 48.6 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KXH42346.1 - 8.1e-08 32.3 0.1 1.2e-07 31.8 0.1 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KXH42346.1 - 0.00035 20.2 0.1 0.0018 17.9 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KXH42346.1 - 0.00043 19.7 0.1 0.00065 19.1 0.1 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KXH42346.1 - 0.00054 19.9 0.8 0.018 15.0 0.1 2.1 1 1 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 KXH42346.1 - 0.0031 17.8 0.0 0.019 15.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain SRPRB PF09439.10 KXH42346.1 - 0.015 14.7 0.0 0.026 13.9 0.0 1.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_14 PF13173.6 KXH42346.1 - 0.018 15.1 0.1 0.047 13.7 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KXH42346.1 - 0.02 15.3 0.1 0.032 14.6 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 KXH42346.1 - 0.022 15.2 0.1 0.032 14.7 0.1 1.4 1 1 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 KXH42346.1 - 0.03 14.1 0.1 0.064 13.0 0.1 1.7 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 KXH42346.1 - 0.033 13.6 0.0 0.17 11.3 0.0 1.9 2 0 0 2 2 2 0 Bacterial TniB protein AAA_21 PF13304.6 KXH42346.1 - 0.095 12.5 0.5 0.14 11.9 0.5 1.4 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system SpoIIID PF12116.8 KXH42346.1 - 0.1 12.7 0.1 1.9 8.6 0.0 2.2 2 0 0 2 2 2 0 Stage III sporulation protein D FeoB_N PF02421.18 KXH42346.1 - 0.1 12.1 0.0 0.24 10.9 0.0 1.6 2 0 0 2 2 2 0 Ferrous iron transport protein B MCM PF00493.23 KXH42346.1 - 0.11 11.5 0.0 0.22 10.6 0.0 1.5 1 1 0 1 1 1 0 MCM P-loop domain AAA_7 PF12775.7 KXH42346.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Brix PF04427.18 KXH42347.1 - 3.7e-33 115.3 0.0 5.5e-33 114.7 0.0 1.2 1 0 0 1 1 1 1 Brix domain F-box-like PF12937.7 KXH42348.1 - 0.0013 18.6 1.2 0.047 13.6 0.0 2.7 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 KXH42348.1 - 0.0018 18.1 0.0 0.004 17.0 0.0 1.5 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 KXH42348.1 - 0.02 14.8 0.0 0.036 13.9 0.0 1.4 1 0 0 1 1 1 0 F-box Arb2 PF09757.9 KXH42349.1 - 2.1e-95 318.7 0.0 3.9e-95 317.9 0.0 1.4 1 0 0 1 1 1 1 Arb2 domain Hist_deacetyl PF00850.19 KXH42349.1 - 8.3e-82 275.1 0.0 1.9e-81 273.9 0.0 1.6 2 0 0 2 2 2 1 Histone deacetylase domain Fzo_mitofusin PF04799.13 KXH42350.1 - 0.18 11.3 0.3 0.24 10.9 0.3 1.1 1 0 0 1 1 1 0 fzo-like conserved region VEFS-Box PF09733.9 KXH42352.1 - 5.1e-06 26.3 0.0 1e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 VEFS-Box of polycomb protein PHD PF00628.29 KXH42352.1 - 0.0012 18.7 3.7 0.0012 18.7 3.7 2.1 3 0 0 3 3 3 1 PHD-finger MTHFR_C PF12225.8 KXH42352.1 - 0.31 10.7 2.5 0.77 9.5 2.5 1.6 1 0 0 1 1 1 0 Methylene-tetrahydrofolate reductase C terminal zf-C2H2 PF00096.26 KXH42352.1 - 2.1 9.0 5.8 2.3 8.8 0.4 3.4 3 0 0 3 3 3 0 Zinc finger, C2H2 type DUF382 PF04037.13 KXH42353.1 - 1.4e-58 196.6 0.8 1.4e-58 196.6 0.8 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF382) PSP PF04046.16 KXH42353.1 - 5.7e-18 64.5 3.5 1.1e-17 63.6 3.5 1.5 1 0 0 1 1 1 1 PSP COX4 PF02936.14 KXH42353.1 - 0.21 11.6 3.1 0.22 11.5 0.1 2.5 3 0 0 3 3 3 0 Cytochrome c oxidase subunit IV TPT PF03151.16 KXH42354.1 - 1.1e-56 192.4 10.5 1.3e-56 192.1 10.5 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KXH42354.1 - 4.2e-11 43.2 30.8 1e-05 25.7 11.0 3.3 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 KXH42354.1 - 4.6e-06 26.0 16.1 9.3e-05 21.8 16.1 2.1 1 1 0 1 1 1 1 UAA transporter family PUNUT PF16913.5 KXH42354.1 - 0.0054 16.0 11.1 0.0073 15.6 10.6 1.4 1 1 0 1 1 1 1 Purine nucleobase transmembrane transport Multi_Drug_Res PF00893.19 KXH42354.1 - 6.7 7.4 9.7 4.9 7.9 0.7 3.6 2 1 1 4 4 4 0 Small Multidrug Resistance protein ORC5_C PF14630.6 KXH42355.1 - 1.8e-85 286.9 0.0 5.2e-85 285.4 0.0 1.7 2 0 0 2 2 2 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.6 KXH42355.1 - 2.6e-18 67.0 0.0 4.7e-18 66.1 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain TniB PF05621.11 KXH42355.1 - 0.01 15.2 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein FtsK_SpoIIIE PF01580.18 KXH42355.1 - 0.088 12.1 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF815 PF05673.13 KXH42355.1 - 0.16 11.1 0.0 0.39 9.8 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_22 PF13401.6 KXH42355.1 - 0.17 12.1 0.0 0.4 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KXH42355.1 - 0.21 11.1 0.0 0.37 10.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Zn_clus PF00172.18 KXH42356.1 - 1.7e-07 31.2 12.4 2.7e-07 30.6 12.4 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KXH42356.1 - 0.0094 14.8 0.0 0.014 14.3 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KXH42357.1 - 4.8e-05 23.6 58.2 0.061 13.8 0.2 9.0 10 0 0 10 10 10 5 Zinc finger, C2H2 type zf-C2H2_11 PF16622.5 KXH42357.1 - 0.00074 19.2 2.3 0.63 9.9 0.1 3.8 3 0 0 3 3 3 2 zinc-finger C2H2-type Actin_micro PF17003.5 KXH42357.1 - 0.0061 15.8 0.6 0.04 13.1 0.0 2.1 1 1 1 2 2 2 1 Putative actin-like family zf-C2H2_4 PF13894.6 KXH42357.1 - 0.0085 16.8 48.4 1.1 10.3 0.1 9.4 9 2 0 9 9 9 4 C2H2-type zinc finger zf-C2HC_2 PF13913.6 KXH42357.1 - 0.0097 15.8 3.4 0.0097 15.8 3.4 4.5 5 0 0 5 5 5 1 zinc-finger of a C2HC-type zf-C2H2_8 PF15909.5 KXH42357.1 - 0.023 15.0 0.5 0.023 15.0 0.5 2.8 3 1 0 3 3 3 0 C2H2-type zinc ribbon zf-DBF PF07535.12 KXH42357.1 - 0.031 14.4 1.8 0.031 14.4 1.8 3.4 4 0 0 4 4 4 0 DBF zinc finger zf-C2H2_2 PF12756.7 KXH42357.1 - 0.048 14.0 23.1 0.51 10.7 2.3 5.0 1 1 1 5 5 5 0 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.6 KXH42357.1 - 0.2 12.2 0.4 0.2 12.2 0.4 7.1 8 2 0 8 8 8 0 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KXH42357.1 - 1.9 8.9 30.7 0.32 11.4 1.8 6.3 7 0 0 7 7 7 0 Zinc-finger double-stranded RNA-binding AMP-binding PF00501.28 KXH42358.1 - 4.2e-79 266.1 0.0 7.4e-76 255.4 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.20 KXH42358.1 - 1.1e-59 202.4 0.0 1.9e-32 112.6 0.0 3.2 3 0 0 3 3 3 2 Condensation domain PP-binding PF00550.25 KXH42358.1 - 1.7e-26 92.4 0.5 5.7e-12 45.8 0.0 3.3 3 0 0 3 3 3 2 Phosphopantetheine attachment site JmjN PF02375.17 KXH42358.1 - 0.1 12.6 0.6 0.71 9.9 0.1 2.3 2 0 0 2 2 2 0 jmjN domain Acetyltransf_1 PF00583.25 KXH42359.1 - 7.1e-07 29.5 0.0 9.6e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXH42359.1 - 4.8e-05 23.7 0.0 0.0001 22.7 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KXH42359.1 - 6.1e-05 23.0 0.0 0.00015 21.7 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXH42359.1 - 0.12 12.4 0.1 1 9.3 0.1 2.1 1 1 0 1 1 1 0 FR47-like protein AMP-binding PF00501.28 KXH42361.1 - 7.5e-99 331.2 0.0 9.6e-99 330.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXH42361.1 - 2.9e-13 50.6 0.0 6.5e-13 49.5 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Methyltransf_25 PF13649.6 KXH42362.1 - 3.1e-05 24.6 0.0 0.00017 22.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXH42362.1 - 0.003 17.4 0.0 0.0046 16.8 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 KXH42362.1 - 0.0036 16.9 0.0 0.095 12.3 0.0 2.2 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW PCMT PF01135.19 KXH42362.1 - 0.0087 15.8 0.0 0.014 15.2 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_11 PF08241.12 KXH42362.1 - 0.012 16.3 0.0 0.18 12.5 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_24 PF13578.6 KXH42362.1 - 0.022 15.8 0.0 0.049 14.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 KXH42362.1 - 0.047 13.5 0.0 0.33 10.8 0.1 2.0 2 0 0 2 2 2 0 Methyltransferase domain CMAS PF02353.20 KXH42362.1 - 0.21 10.9 0.0 0.28 10.4 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Acetyltransf_8 PF13523.6 KXH42363.1 - 4.1e-46 156.3 2.9 6.2e-46 155.7 2.9 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KXH42363.1 - 0.029 15.0 0.4 0.062 14.0 0.4 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Glyco_transf_41 PF13844.6 KXH42380.1 - 9.3e-102 340.9 0.0 2e-52 178.2 0.0 3.3 1 1 1 2 2 2 2 Glycosyl transferase family 41 TPR_1 PF00515.28 KXH42380.1 - 3.1e-21 74.2 1.4 0.0014 18.4 0.0 6.5 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 KXH42380.1 - 3.4e-19 67.3 1.3 0.021 14.9 0.1 6.8 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.6 KXH42380.1 - 1.1e-12 47.0 0.4 0.0062 16.7 0.0 6.2 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 KXH42380.1 - 1.4e-11 43.8 6.2 0.0049 16.5 0.0 6.1 3 2 3 6 6 6 4 TPR repeat TPR_17 PF13431.6 KXH42380.1 - 1.3e-09 37.8 1.8 0.0081 16.5 0.1 5.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 KXH42380.1 - 3e-09 37.0 3.1 0.0061 16.8 0.2 4.9 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 KXH42380.1 - 4.8e-09 36.3 0.6 1.5 9.8 0.0 6.1 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_10 PF13374.6 KXH42380.1 - 1.4e-08 34.3 4.9 0.095 12.6 0.0 5.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 KXH42380.1 - 1.7e-08 34.9 1.7 0.54 11.0 0.0 5.2 6 0 0 6 6 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 KXH42380.1 - 1.3e-07 31.1 0.1 0.011 15.7 0.0 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KXH42380.1 - 1.9e-05 25.1 4.8 0.029 14.9 0.1 4.3 4 1 2 6 6 6 3 Tetratricopeptide repeat TPR_9 PF13371.6 KXH42380.1 - 0.001 19.2 0.7 0.45 10.7 0.1 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat BTAD PF03704.17 KXH42380.1 - 0.41 11.1 3.7 1.5 9.3 0.0 3.3 4 0 0 4 4 4 0 Bacterial transcriptional activator domain Ribosomal_L11_N PF03946.14 KXH42381.1 - 1.1e-24 86.0 0.1 1.9e-24 85.3 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 KXH42381.1 - 3.2e-16 59.6 0.2 5.1e-16 58.9 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Sec23_trunk PF04811.15 KXH42382.1 - 2.9e-78 262.8 0.0 4e-78 262.3 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 KXH42382.1 - 4.5e-31 107.5 0.3 9.3e-31 106.4 0.3 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 KXH42382.1 - 1.1e-25 89.4 0.1 4.5e-25 87.5 0.1 2.1 2 0 0 2 2 2 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 KXH42382.1 - 1.3e-15 57.1 5.7 2.5e-15 56.2 5.7 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 KXH42382.1 - 3.1e-12 46.2 0.0 9.3e-12 44.7 0.0 1.9 2 0 0 2 2 2 1 Gelsolin repeat Vps36-NZF-N PF16988.5 KXH42382.1 - 0.038 13.4 0.7 0.099 12.1 0.1 1.9 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Suc_Fer-like PF06999.12 KXH42404.1 - 3e-58 196.9 0.0 5.1e-58 196.2 0.0 1.4 2 0 0 2 2 2 1 Sucrase/ferredoxin-like FAD_binding_6 PF00970.24 KXH42406.1 - 7.8e-05 23.0 0.0 0.00057 20.2 0.0 2.5 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 KXH42406.1 - 0.0058 17.3 0.0 0.02 15.5 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain PhoLip_ATPase_C PF16212.5 KXH42407.1 - 8.7e-51 173.1 5.8 8.7e-51 173.1 5.8 2.0 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KXH42407.1 - 2.3e-16 59.2 0.5 6.2e-16 57.9 0.5 1.7 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KXH42407.1 - 6.6e-14 52.7 0.0 1.7e-07 31.8 0.0 3.4 3 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KXH42407.1 - 5.9e-08 32.5 1.3 0.00069 19.2 0.1 2.8 2 0 0 2 2 2 2 E1-E2 ATPase Cation_ATPase PF13246.6 KXH42407.1 - 0.00011 22.2 0.0 0.0023 18.0 0.0 2.4 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KXH42407.1 - 0.0019 18.0 0.0 0.0038 17.0 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase TerB_C PF15615.6 KXH42407.1 - 2.3 8.5 5.4 12 6.2 0.2 2.9 3 0 0 3 3 3 0 TerB-C domain Sec16_C PF12931.7 KXH42408.1 - 2.1e-114 382.3 0.0 2.9e-114 381.8 0.0 1.2 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.7 KXH42408.1 - 5.6e-35 120.5 0.0 1.9e-34 118.8 0.0 2.0 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region Nup96 PF12110.8 KXH42408.1 - 0.009 15.2 0.0 0.02 14.0 0.0 1.6 1 0 0 1 1 1 1 Nuclear protein 96 DUF1604 PF07713.13 KXH42408.1 - 2.7 7.9 5.5 1.7 8.5 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1604) DUF3684 PF12449.8 KXH42409.1 - 0 1524.9 0.1 0 1524.5 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) HATPase_c_3 PF13589.6 KXH42409.1 - 0.00012 21.9 0.0 0.00041 20.2 0.0 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase WLM PF08325.10 KXH42409.1 - 0.15 12.1 0.1 1 9.4 0.1 2.2 2 0 0 2 2 2 0 WLM domain Myosin_tail_1 PF01576.19 KXH42409.1 - 0.17 9.7 6.1 0.26 9.1 6.1 1.1 1 0 0 1 1 1 0 Myosin tail Reprolysin_5 PF13688.6 KXH42409.1 - 0.5 10.5 2.2 1.2 9.2 2.2 1.7 1 1 0 1 1 1 0 Metallo-peptidase family M12 HET PF06985.11 KXH42410.1 - 1.9e-13 51.0 3.8 1.6e-10 41.5 0.4 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) NmrA PF05368.13 KXH42411.1 - 3.8e-20 72.5 0.1 4.9e-20 72.1 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXH42411.1 - 9.3e-14 51.7 0.0 1.5e-13 51.1 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding Shikimate_DH PF01488.20 KXH42411.1 - 6.2e-05 23.1 0.0 0.00012 22.1 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DapB_N PF01113.20 KXH42411.1 - 0.00016 21.7 0.2 0.00046 20.3 0.0 1.7 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus Epimerase PF01370.21 KXH42411.1 - 0.0005 19.6 0.0 0.059 12.8 0.0 2.6 2 1 1 3 3 3 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 KXH42411.1 - 0.049 14.1 0.0 0.097 13.1 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Porin_3 PF01459.22 KXH42412.1 - 1.1e-87 294.0 1.0 1.2e-87 293.8 1.0 1.0 1 0 0 1 1 1 1 Eukaryotic porin 6PF2K PF01591.18 KXH42413.1 - 7.6e-61 205.2 0.0 1.2e-60 204.6 0.0 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 KXH42413.1 - 1.8e-21 76.7 0.2 7.9e-21 74.6 0.2 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 KXH42413.1 - 0.0061 16.7 0.0 0.05 13.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain ZnuA PF01297.17 KXH42413.1 - 0.077 12.4 0.1 0.26 10.7 0.0 1.9 1 1 1 2 2 2 0 Zinc-uptake complex component A periplasmic UCH_1 PF13423.6 KXH42414.1 - 6e-39 134.5 0.0 2e-38 132.8 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH PF00443.29 KXH42414.1 - 8.5e-17 61.5 0.0 2.3e-16 60.1 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Ribosomal_L5_C PF00673.21 KXH42415.1 - 1e-24 86.5 0.0 1.5e-24 85.9 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 KXH42415.1 - 2.2e-07 31.1 0.2 3.6e-07 30.4 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L5 Fes1 PF08609.10 KXH42416.1 - 3.2e-30 104.9 2.2 3.7e-30 104.6 0.7 1.8 2 0 0 2 2 2 1 Nucleotide exchange factor Fes1 Arm PF00514.23 KXH42416.1 - 7.7e-07 28.9 0.3 0.033 14.2 0.0 2.7 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KXH42416.1 - 2.3e-06 28.0 0.8 1.6e-05 25.3 0.3 2.3 2 0 0 2 2 2 1 HEAT-like repeat HEAT_2 PF13646.6 KXH42416.1 - 3e-05 24.3 0.8 0.00011 22.6 0.1 2.1 2 1 0 2 2 2 1 HEAT repeats HEAT PF02985.22 KXH42416.1 - 5.8e-05 23.0 0.2 0.2 12.0 0.1 2.9 2 0 0 2 2 2 2 HEAT repeat AAA_13 PF13166.6 KXH42416.1 - 0.074 11.7 0.1 0.093 11.4 0.1 1.3 1 1 0 1 1 1 0 AAA domain Actin PF00022.19 KXH42418.1 - 5.7e-150 499.4 0.0 2.1e-149 497.6 0.0 1.7 1 1 0 1 1 1 1 Actin RF-1 PF00472.20 KXH42419.1 - 4.8e-23 81.3 5.9 4.8e-23 81.3 5.9 1.4 1 1 0 1 1 1 1 RF-1 domain S-antigen PF05756.11 KXH42419.1 - 0.18 12.2 2.6 0.3 11.5 2.6 1.3 1 0 0 1 1 1 0 S-antigen protein SPT_ssu-like PF11779.8 KXH42420.1 - 5.5e-21 73.9 5.6 7.3e-21 73.5 5.6 1.2 1 0 0 1 1 1 1 Small subunit of serine palmitoyltransferase-like WD40 PF00400.32 KXH42421.1 - 8.5e-30 102.4 19.5 0.00093 20.0 0.2 11.6 12 0 0 12 12 12 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXH42421.1 - 8.8e-07 29.1 0.5 1 9.7 0.1 6.4 5 3 1 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KXH42421.1 - 0.00096 18.2 0.4 1.6 7.6 0.3 3.9 3 1 2 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Urm1 PF09138.11 KXH42422.1 - 2.2e-33 114.5 0.0 2.5e-33 114.3 0.0 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.20 KXH42422.1 - 0.0015 19.1 0.1 0.004 17.8 0.0 1.7 2 0 0 2 2 2 1 ThiS family DJ-1_PfpI PF01965.24 KXH42423.1 - 1.1e-15 57.9 0.0 1.5e-15 57.4 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family Cupin_5 PF06172.11 KXH42423.1 - 0.16 12.2 0.1 0.58 10.3 0.1 1.9 2 1 1 3 3 3 0 Cupin superfamily (DUF985) DIT1_PvcA PF05141.12 KXH42424.1 - 2.4e-105 351.9 0.0 3.1e-105 351.6 0.0 1.1 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein YopE_N PF09020.10 KXH42424.1 - 0.21 11.8 0.8 0.82 9.9 0.2 2.2 2 0 0 2 2 2 0 YopE, N terminal p450 PF00067.22 KXH42425.1 - 2.7e-54 184.7 0.0 3.4e-54 184.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 BatA PF07584.11 KXH42425.1 - 0.22 11.9 3.6 15 6.1 1.9 2.5 2 0 0 2 2 2 0 Aerotolerance regulator N-terminal MFS_1 PF07690.16 KXH42426.1 - 3.4e-44 151.2 54.8 8.4e-42 143.3 30.0 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH42426.1 - 1.4e-13 50.6 6.4 1.4e-13 50.6 6.4 2.7 3 0 0 3 3 3 1 Sugar (and other) transporter OATP PF03137.20 KXH42426.1 - 4 5.6 14.7 0.096 11.0 2.7 3.3 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family SPC25 PF06703.11 KXH42426.1 - 5.8 6.7 7.0 0.3 10.9 0.5 2.1 2 0 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Hydrolase PF00702.26 KXH42427.1 - 2.6e-08 34.4 0.0 6.9e-08 33.0 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KXH42427.1 - 0.0081 16.3 0.0 0.011 15.8 0.0 1.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 KXH42427.1 - 0.04 14.0 0.0 11 6.2 0.0 2.3 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase DAO PF01266.24 KXH42428.1 - 1.4e-45 156.5 0.5 1.6e-45 156.3 0.5 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KXH42428.1 - 0.00017 21.6 0.7 0.11 12.5 0.0 2.7 3 0 0 3 3 3 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KXH42428.1 - 0.01 15.1 0.9 5.3 6.2 1.5 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXH42428.1 - 0.013 14.7 0.2 0.083 12.1 0.1 2.2 2 1 1 3 3 3 0 Thi4 family HI0933_like PF03486.14 KXH42428.1 - 0.02 13.6 0.1 0.19 10.4 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_8 PF13450.6 KXH42428.1 - 0.023 14.9 0.1 0.053 13.8 0.1 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain MFS_1 PF07690.16 KXH42429.1 - 6.4e-09 35.2 20.8 6.4e-09 35.2 20.8 3.0 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH42429.1 - 2.2e-06 26.8 6.5 2.2e-06 26.8 6.5 1.7 2 0 0 2 2 2 1 Sugar (and other) transporter UNC-93 PF05978.16 KXH42429.1 - 0.00013 21.7 6.8 0.00025 20.8 6.8 1.5 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 GATA PF00320.27 KXH42429.1 - 0.013 15.1 1.0 0.027 14.1 1.0 1.5 1 0 0 1 1 1 0 GATA zinc finger PUCC PF03209.15 KXH42429.1 - 0.04 12.9 3.9 0.072 12.1 3.9 1.4 1 0 0 1 1 1 0 PUCC protein zf-C2H2 PF00096.26 KXH42430.1 - 1.8e-22 78.5 23.2 5.2e-06 26.6 0.9 4.8 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KXH42430.1 - 2e-18 65.9 27.8 4.2e-09 36.4 1.0 5.0 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KXH42430.1 - 7.4e-14 51.3 20.2 0.00023 21.7 0.5 4.7 4 0 0 4 4 4 4 C2H2-type zinc finger zf-met PF12874.7 KXH42430.1 - 0.00021 21.5 12.2 2.2 8.8 0.5 4.7 4 0 0 4 4 4 3 Zinc-finger of C2H2 type FOXP-CC PF16159.5 KXH42430.1 - 0.0005 20.7 11.0 0.016 15.8 1.1 4.0 1 1 3 4 4 4 2 FOXP coiled-coil domain zf-H2C2_5 PF13909.6 KXH42430.1 - 0.00064 19.4 14.6 0.0026 17.5 0.2 4.0 3 1 0 3 3 3 2 C2H2-type zinc-finger domain zf-C2H2_aberr PF17017.5 KXH42430.1 - 0.00074 19.7 4.5 3.1 7.9 0.0 3.5 2 1 1 3 3 3 2 Aberrant zinc-finger zf-C2H2_jaz PF12171.8 KXH42430.1 - 0.0059 16.9 8.7 0.5 10.7 0.1 4.2 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 KXH42430.1 - 0.012 15.9 7.6 0.051 13.9 3.5 3.2 1 1 2 3 3 3 0 C2H2-type zinc ribbon zf-C2H2_6 PF13912.6 KXH42430.1 - 0.022 14.7 0.7 0.022 14.7 0.7 4.2 4 0 0 4 4 4 0 C2H2-type zinc finger zf-LYAR PF08790.11 KXH42430.1 - 0.44 10.5 7.8 20 5.2 0.1 4.2 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger zf-DNA_Pol PF08996.10 KXH42430.1 - 2.4 7.9 8.3 2.4 7.9 3.1 2.3 1 1 1 2 2 2 0 DNA Polymerase alpha zinc finger Mito_carr PF00153.27 KXH42431.1 - 2.7e-47 158.7 2.7 1.6e-19 69.6 0.4 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Tom7 PF08038.12 KXH42432.1 - 1.5e-20 72.6 0.2 1.7e-20 72.4 0.2 1.0 1 0 0 1 1 1 1 TOM7 family DUF5049 PF16468.5 KXH42432.1 - 0.11 12.4 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5049) RRM_1 PF00076.22 KXH42433.1 - 1e-32 111.7 0.0 1.9e-15 56.4 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KXH42433.1 - 0.0015 18.6 0.0 0.0039 17.3 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif OB_RNB PF08206.11 KXH42433.1 - 0.0021 17.7 0.7 0.29 10.9 0.1 2.4 2 0 0 2 2 2 2 Ribonuclease B OB domain Nup35_RRM_2 PF14605.6 KXH42433.1 - 0.008 16.2 0.0 0.06 13.4 0.0 2.1 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 KXH42433.1 - 0.048 13.3 0.0 0.17 11.5 0.0 1.8 1 1 1 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pet127 PF08634.10 KXH42434.1 - 1e-118 395.8 2.5 1.6e-118 395.1 2.5 1.3 1 0 0 1 1 1 1 Mitochondrial protein Pet127 Cohesin_load PF10345.9 KXH42435.1 - 1.7e-135 452.8 0.0 2.2e-135 452.4 0.0 1.0 1 0 0 1 1 1 1 Cohesin loading factor Abhydrolase_1 PF00561.20 KXH42436.1 - 1.5e-11 44.4 0.1 2.1e-10 40.7 0.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXH42436.1 - 1.2e-08 34.5 0.0 4.2e-08 32.8 0.0 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DUF5301 PF17225.3 KXH42437.1 - 0.15 12.5 6.8 0.11 13.0 2.8 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF5300) DUF4554 PF15091.6 KXH42437.1 - 1.1 8.0 7.7 1.5 7.6 7.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) CDC45 PF02724.14 KXH42437.1 - 1.4 7.1 9.5 1.5 7.0 9.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Asp-B-Hydro_N PF05279.11 KXH42437.1 - 1.6 8.7 13.9 2.1 8.4 13.9 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DDHD PF02862.17 KXH42437.1 - 4.4 7.4 6.9 6 6.9 6.9 1.3 1 0 0 1 1 1 0 DDHD domain tRNA_bind_2 PF13725.6 KXH42437.1 - 4.8 6.8 10.7 7.8 6.1 10.7 1.3 1 0 0 1 1 1 0 Possible tRNA binding domain ArgJ PF01960.18 KXH42438.1 - 9.2e-149 495.3 0.1 1e-148 495.1 0.1 1.0 1 0 0 1 1 1 1 ArgJ family Acyl-CoA_dh_1 PF00441.24 KXH42439.1 - 8.6e-27 94.2 0.1 1.7e-26 93.2 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KXH42439.1 - 2.2e-20 72.7 0.0 3.6e-20 72.0 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KXH42439.1 - 4.1e-14 53.2 0.0 7.5e-14 52.4 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KXH42439.1 - 7.8e-13 48.9 1.1 1.1e-12 48.4 0.2 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Spo12 PF05032.12 KXH42440.1 - 1.9e-15 56.4 0.7 5.1e-15 55.1 0.7 1.8 1 0 0 1 1 1 1 Spo12 family MRP-L51 PF10244.9 KXH42440.1 - 0.034 14.4 0.0 0.065 13.5 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal subunit MMR_HSR1_Xtn PF16897.5 KXH42441.1 - 2.9e-35 120.5 2.1 6.8e-35 119.3 0.7 2.1 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 KXH42441.1 - 8.2e-21 74.2 0.0 2.2e-20 72.8 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.21 KXH42441.1 - 1.9e-19 69.4 0.1 3.4e-19 68.7 0.1 1.4 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 KXH42441.1 - 1.9e-12 47.0 0.0 3.1e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KXH42441.1 - 5.2e-05 23.4 0.2 0.036 14.1 0.0 2.6 1 1 1 2 2 2 2 Dynamin family MeaB PF03308.16 KXH42441.1 - 0.072 12.1 0.2 0.2 10.6 0.1 1.8 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ADH_N_2 PF16884.5 KXH42441.1 - 0.16 11.9 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase Torus PF16131.5 KXH42442.1 - 5.8e-46 155.7 1.3 7.2e-46 155.4 0.1 1.8 2 0 0 2 2 2 1 Torus domain RRM_1 PF00076.22 KXH42442.1 - 7.2e-08 32.1 0.0 1.2e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 KXH42442.1 - 0.00014 21.8 0.6 0.00014 21.8 0.6 1.9 2 0 0 2 2 2 1 Zinc finger domain zf-CCCH PF00642.24 KXH42442.1 - 0.011 15.7 0.7 0.021 14.7 0.7 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Nup35_RRM_2 PF14605.6 KXH42442.1 - 0.031 14.3 0.0 0.062 13.3 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif NBD_C PF17042.5 KXH42442.1 - 0.28 11.7 3.4 0.97 9.9 0.1 2.4 3 0 0 3 3 3 0 Nucleotide-binding C-terminal domain UreF PF01730.16 KXH42443.1 - 3.7e-22 79.3 0.9 6.7e-22 78.5 0.9 1.4 1 0 0 1 1 1 1 UreF Rep_fac_C PF08542.11 KXH42445.1 - 8.3e-23 80.6 0.0 2.5e-22 79.1 0.0 1.9 2 0 0 2 2 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 KXH42445.1 - 4.4e-12 46.1 0.0 1.1e-08 35.1 0.0 2.3 1 1 1 2 2 2 2 DNA polymerase III, delta subunit AAA PF00004.29 KXH42445.1 - 1.7e-11 44.7 0.0 3.5e-11 43.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 KXH42445.1 - 3.2e-07 30.4 0.0 7.4e-07 29.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KXH42445.1 - 2.2e-06 28.1 0.0 0.00018 21.9 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KXH42445.1 - 8.6e-05 22.8 0.1 0.22 11.8 0.0 2.6 1 1 1 2 2 2 2 AAA domain RuvB_N PF05496.12 KXH42445.1 - 9.3e-05 22.2 0.0 0.00021 21.1 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Viral_helicase1 PF01443.18 KXH42445.1 - 0.00014 21.6 0.0 0.00024 20.9 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_3 PF07726.11 KXH42445.1 - 0.00029 20.7 0.0 0.00055 19.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta PF06144.13 KXH42445.1 - 0.0017 18.2 0.0 0.0028 17.5 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Mg_chelatase PF01078.21 KXH42445.1 - 0.0035 16.7 0.0 0.032 13.6 0.0 2.1 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI Rad17 PF03215.15 KXH42445.1 - 0.0044 17.0 0.0 0.0088 16.0 0.0 1.5 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_assoc_2 PF16193.5 KXH42445.1 - 0.0053 17.1 0.0 0.019 15.3 0.0 2.0 2 0 0 2 2 1 1 AAA C-terminal domain MeaB PF03308.16 KXH42445.1 - 0.0055 15.7 0.0 0.0098 14.9 0.0 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_24 PF13479.6 KXH42445.1 - 0.0061 16.3 0.0 0.029 14.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 KXH42445.1 - 0.0097 15.7 0.0 0.014 15.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain TniB PF05621.11 KXH42445.1 - 0.011 15.1 0.0 3.8 6.9 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein DEAD PF00270.29 KXH42445.1 - 0.014 15.2 0.2 0.58 9.9 0.0 2.4 1 1 1 2 2 2 0 DEAD/DEAH box helicase AAA_19 PF13245.6 KXH42445.1 - 0.015 15.6 0.1 0.046 14.0 0.2 1.9 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KXH42445.1 - 0.018 15.0 0.3 0.071 13.0 0.1 2.0 1 1 1 2 2 2 0 NTPase KTI12 PF08433.10 KXH42445.1 - 0.023 14.2 0.0 0.04 13.4 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 DNA_pol3_gamma3 PF12169.8 KXH42445.1 - 0.026 14.5 0.2 0.57 10.1 0.0 2.8 3 0 0 3 3 3 0 DNA polymerase III subunits gamma and tau domain III AAA_5 PF07728.14 KXH42445.1 - 0.06 13.3 0.1 0.51 10.3 0.1 2.4 3 1 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 KXH42445.1 - 0.09 12.3 0.1 0.68 9.5 0.1 2.2 2 1 1 3 3 3 0 AAA domain AAA_30 PF13604.6 KXH42445.1 - 0.091 12.5 0.1 0.26 11.0 0.1 1.7 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 KXH42446.1 - 4.3e-16 59.0 0.0 6.9e-16 58.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KXH42446.1 - 1.3e-06 28.1 0.1 1.8e-06 27.6 0.1 1.2 1 0 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KXH42446.1 - 0.00037 20.5 0.0 0.00054 19.9 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AIG1 PF04548.16 KXH42446.1 - 0.0021 17.4 0.1 0.003 16.9 0.1 1.2 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.23 KXH42446.1 - 0.0051 16.9 1.1 0.053 13.6 0.5 2.5 3 1 1 4 4 4 1 Dynamin family Ribosomal_S9 PF00380.19 KXH42453.1 - 7.1e-41 139.5 0.3 1.1e-40 138.9 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein S9/S16 EF-hand_9 PF14658.6 KXH42453.1 - 0.17 12.2 0.0 0.4 11.0 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain EF1G PF00647.19 KXH42454.1 - 1.5e-44 150.4 0.7 2.7e-44 149.6 0.7 1.4 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.25 KXH42454.1 - 7.6e-14 51.7 0.0 1.8e-13 50.5 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KXH42454.1 - 3.7e-11 43.2 0.0 9.1e-11 42.0 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KXH42454.1 - 1.3e-08 34.7 0.3 4.4e-08 33.0 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KXH42454.1 - 0.00045 20.4 0.0 0.0012 18.9 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KXH42454.1 - 0.00054 20.3 0.0 0.0011 19.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DEC-1_N PF04625.13 KXH42454.1 - 0.019 14.0 2.3 0.028 13.5 2.3 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region NIF PF03031.18 KXH42455.1 - 1.1e-19 70.8 0.0 2e-19 69.9 0.0 1.5 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase RRP36 PF06102.12 KXH42456.1 - 8.2e-57 191.8 32.5 8.2e-57 191.8 32.5 1.6 2 0 0 2 2 2 1 rRNA biogenesis protein RRP36 Sec16 PF12932.7 KXH42456.1 - 0.16 12.6 2.0 0.2 12.3 0.7 1.8 1 1 0 1 1 1 0 Vesicle coat trafficking protein Sec16 mid-region Filaggrin PF03516.13 KXH42456.1 - 7.7 7.3 11.0 0.61 10.8 4.1 2.6 1 1 1 2 2 2 0 Filaggrin ABC1 PF03109.16 KXH42457.1 - 5.1e-32 110.5 0.0 8.9e-32 109.8 0.0 1.4 1 0 0 1 1 1 1 ABC1 family Es2 PF09751.9 KXH42458.1 - 1.1e-122 410.9 5.7 1.3e-122 410.6 5.7 1.1 1 0 0 1 1 1 1 Nuclear protein Es2 PPP5 PF08321.12 KXH42459.1 - 1.3e-33 115.2 0.3 9.8e-33 112.3 0.0 2.2 2 0 0 2 2 2 1 PPP5 TPR repeat region Metallophos PF00149.28 KXH42459.1 - 4.1e-31 109.1 0.0 5.8e-31 108.6 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TPR_1 PF00515.28 KXH42459.1 - 2.9e-17 61.7 0.8 0.00025 20.7 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KXH42459.1 - 3.9e-12 45.3 0.3 0.0065 16.5 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 KXH42459.1 - 2.1e-11 43.3 1.0 0.00086 18.9 0.0 3.3 3 0 0 3 3 3 2 TPR repeat TPR_17 PF13431.6 KXH42459.1 - 1.1e-07 31.7 1.1 0.068 13.6 0.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_9 PF13371.6 KXH42459.1 - 0.00014 21.9 0.0 0.091 12.9 0.0 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 KXH42459.1 - 0.00076 19.5 1.0 20 5.7 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 KXH42459.1 - 0.0046 17.4 0.0 7.1 7.2 0.0 3.1 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 KXH42459.1 - 0.022 15.5 0.0 43 5.3 0.0 3.6 2 1 1 3 3 3 0 Tetratricopeptide repeat Spt4 PF06093.13 KXH42461.1 - 7.7e-33 112.4 0.3 9.5e-33 112.2 0.3 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger Coronavirus_5 PF05528.11 KXH42461.1 - 0.032 14.2 0.3 0.12 12.3 0.1 1.9 1 1 1 2 2 2 0 Coronavirus gene 5 protein Kin17_mid PF10357.9 KXH42462.1 - 1.3e-50 170.6 2.0 1.3e-50 170.6 2.0 1.9 3 0 0 3 3 3 1 Domain of Kin17 curved DNA-binding protein zf-met PF12874.7 KXH42462.1 - 2.4e-05 24.5 3.4 4.9e-05 23.6 3.4 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KXH42462.1 - 2.5e-05 24.4 2.2 5.9e-05 23.2 2.2 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KXH42462.1 - 0.0093 16.3 0.8 0.0093 16.3 0.8 2.2 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) NOD PF06816.13 KXH42462.1 - 0.015 14.9 0.0 0.031 13.9 0.0 1.5 1 0 0 1 1 1 0 NOTCH protein RPE65 PF03055.15 KXH42463.1 - 2.6e-92 310.4 0.0 3.2e-92 310.2 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Glyco_hydro_7 PF00840.20 KXH42464.1 - 2.4e-152 507.7 8.3 2.7e-152 507.5 8.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 DUF3081 PF11280.8 KXH42464.1 - 0.046 13.5 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3081) GFO_IDH_MocA PF01408.22 KXH42465.1 - 6e-24 85.2 0.1 4.8e-23 82.3 0.1 2.1 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KXH42465.1 - 0.0051 16.8 0.0 0.0095 15.9 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Gp_dh_N PF00044.24 KXH42465.1 - 0.0069 16.7 0.0 0.02 15.3 0.0 1.9 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 KXH42465.1 - 0.14 12.3 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Sugar_tr PF00083.24 KXH42466.1 - 1.4e-106 357.1 18.4 2e-106 356.6 18.4 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH42466.1 - 3.2e-24 85.5 49.4 1.5e-18 66.9 23.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KXH42466.1 - 4.4e-06 25.4 10.0 0.0022 16.5 3.3 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) UNC-93 PF05978.16 KXH42466.1 - 0.28 10.9 11.7 0.24 11.1 1.7 2.7 3 0 0 3 3 3 0 Ion channel regulatory protein UNC-93 GFO_IDH_MocA PF01408.22 KXH42467.1 - 1.9e-21 77.1 0.1 3.9e-21 76.1 0.1 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KXH42467.1 - 3.4e-07 30.3 0.0 6.2e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Mt_ATP_synt PF15704.5 KXH42467.1 - 0.0034 17.3 0.0 0.0055 16.6 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase subunit HTH_3 PF01381.22 KXH42467.1 - 0.065 13.3 0.0 0.18 11.9 0.0 1.7 1 1 0 1 1 1 0 Helix-turn-helix BNR PF02012.20 KXH42469.1 - 5.6e-06 25.6 1.3 0.12 12.5 0.2 3.2 2 0 0 2 2 2 2 BNR/Asp-box repeat Sortilin-Vps10 PF15902.5 KXH42469.1 - 0.0013 17.7 0.5 0.28 9.9 0.0 2.5 3 0 0 3 3 3 2 Sortilin, neurotensin receptor 3, BNR_2 PF13088.6 KXH42469.1 - 0.0016 17.8 0.0 0.014 14.7 0.0 2.2 1 1 0 1 1 1 1 BNR repeat-like domain Cas_TM1802 PF09484.10 KXH42470.1 - 0.014 14.2 0.0 0.027 13.2 0.0 1.4 1 1 0 1 1 1 0 CRISPR-associated protein TM1802 (cas_TM1802) DASH_Spc34 PF08657.10 KXH42470.1 - 0.026 14.3 3.3 0.049 13.4 3.3 1.5 1 0 0 1 1 1 0 DASH complex subunit Spc34 FYVE_2 PF02318.16 KXH42470.1 - 0.084 13.1 1.5 15 5.8 0.1 3.3 3 1 0 3 3 3 0 FYVE-type zinc finger DUF2757 PF10955.8 KXH42470.1 - 0.093 13.0 0.3 0.48 10.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2757) Serine_rich PF08824.10 KXH42470.1 - 0.41 10.6 4.2 1.1 9.3 2.5 2.2 2 0 0 2 2 2 0 Serine rich protein interaction domain Beta-lactamase PF00144.24 KXH42471.1 - 2e-46 158.8 0.0 2.8e-46 158.3 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.8 KXH42471.1 - 3.1e-06 27.6 0.0 5.9e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) 3HCDH_N PF02737.18 KXH42472.1 - 1.7e-30 106.3 0.0 2.5e-30 105.7 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 KXH42472.1 - 1.7e-14 54.2 0.0 3.2e-14 53.3 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain DUF5050 PF16472.5 KXH42472.1 - 9.9e-05 21.7 0.0 0.039 13.2 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF5050) NAD_Gly3P_dh_N PF01210.23 KXH42472.1 - 0.0006 19.8 0.0 0.00094 19.2 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Ldl_recept_b PF00058.17 KXH42472.1 - 0.00095 19.6 0.0 20 5.8 0.0 4.4 4 0 0 4 4 4 2 Low-density lipoprotein receptor repeat class B NAD_binding_2 PF03446.15 KXH42472.1 - 0.0051 17.0 0.0 0.0096 16.1 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Str_synth PF03088.16 KXH42472.1 - 0.015 15.4 0.0 6.6 6.9 0.0 3.2 2 1 0 2 2 2 0 Strictosidine synthase MFS_1 PF07690.16 KXH42473.1 - 5.7e-33 114.3 23.1 5.7e-33 114.3 23.1 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 KXH42473.1 - 1.1e-05 25.0 1.0 1.1e-05 25.0 1.0 2.6 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Amidase PF01425.21 KXH42474.1 - 9.5e-105 351.1 0.0 2.7e-104 349.7 0.0 1.6 1 1 0 1 1 1 1 Amidase tRNA-synt_2c PF01411.19 KXH42475.1 - 4.5e-08 32.1 0.1 5.7e-08 31.7 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 KXH42475.1 - 7.8e-06 25.9 0.5 1.3e-05 25.1 0.5 1.4 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain Glyco_transf_8 PF01501.20 KXH42477.1 - 3.7e-12 46.4 0.0 1.2e-11 44.7 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferase family 8 Tyrosinase PF00264.20 KXH42478.1 - 9.4e-38 130.7 0.4 2.1e-37 129.6 0.4 1.5 1 1 0 1 1 1 1 Common central domain of tyrosinase ADH_zinc_N_2 PF13602.6 KXH42479.1 - 2.5e-25 90.0 0.0 4.1e-25 89.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KXH42479.1 - 1.7e-17 63.6 0.2 3.3e-17 62.7 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PALP PF00291.25 KXH42479.1 - 0.049 13.0 0.0 0.071 12.5 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme ELFV_dehydrog PF00208.21 KXH42479.1 - 0.13 12.0 0.1 0.18 11.5 0.1 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Kelch_1 PF01344.25 KXH42480.1 - 1.7e-47 158.7 7.2 3.8e-09 36.0 0.0 7.0 7 0 0 7 7 7 6 Kelch motif Kelch_6 PF13964.6 KXH42480.1 - 1e-43 146.2 0.3 7.3e-09 35.6 0.0 6.4 5 1 1 6 6 6 6 Kelch motif Kelch_4 PF13418.6 KXH42480.1 - 2.1e-35 120.5 0.9 1.9e-05 24.6 0.0 6.1 5 1 1 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.6 KXH42480.1 - 4.3e-28 97.0 2.6 1.4e-05 25.2 0.0 5.9 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_2 PF07646.15 KXH42480.1 - 9.6e-26 88.7 2.3 6.9e-05 22.7 0.0 7.0 6 2 0 6 6 6 5 Kelch motif Kelch_5 PF13854.6 KXH42480.1 - 1.4e-19 69.6 1.2 0.0032 17.4 0.0 6.1 6 0 0 6 6 6 5 Kelch motif DUF1668 PF07893.13 KXH42480.1 - 0.037 13.4 0.0 3.4 6.9 0.0 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF1668) PQQ_3 PF13570.6 KXH42480.1 - 0.054 14.0 11.6 36 5.0 0.1 5.5 5 1 1 6 6 6 0 PQQ-like domain Fungal_trans_2 PF11951.8 KXH42481.1 - 1.2e-06 27.6 0.8 1.9e-06 26.9 0.8 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain RTA1 PF04479.13 KXH42482.1 - 4.4e-69 232.2 6.4 4.4e-69 232.2 6.4 1.2 1 1 0 1 1 1 1 RTA1 like protein DUF2975 PF11188.8 KXH42482.1 - 2.5 8.0 13.6 1.8 8.5 7.8 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2975) ABC_tran PF00005.27 KXH42483.1 - 5.9e-52 175.8 0.0 5.3e-29 101.5 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KXH42483.1 - 3.9e-23 82.5 31.2 7e-17 62.0 15.1 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 KXH42483.1 - 4e-10 39.5 1.0 0.00044 19.8 0.0 4.2 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KXH42483.1 - 2.4e-09 37.4 1.0 0.029 14.2 0.1 3.6 2 1 1 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KXH42483.1 - 1.3e-08 34.4 2.3 0.0041 16.8 0.0 2.8 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 KXH42483.1 - 7.1e-07 29.6 4.5 0.031 14.5 0.5 3.7 3 1 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 KXH42483.1 - 2.1e-06 27.8 0.3 0.023 14.6 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 KXH42483.1 - 4.3e-06 27.2 0.4 0.19 12.1 0.1 3.1 2 1 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 KXH42483.1 - 8.4e-06 26.4 0.4 0.22 12.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 KXH42483.1 - 1e-05 25.6 0.1 0.24 11.5 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase cobW PF02492.19 KXH42483.1 - 1.9e-05 24.4 0.2 0.023 14.3 0.0 2.5 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 KXH42483.1 - 2.6e-05 24.4 0.0 0.088 13.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain Dynamin_N PF00350.23 KXH42483.1 - 0.00012 22.2 1.0 0.047 13.8 0.0 2.7 3 0 0 3 3 2 1 Dynamin family AAA_30 PF13604.6 KXH42483.1 - 0.00021 21.1 0.0 0.25 11.0 0.0 2.6 3 0 0 3 3 2 1 AAA domain T2SSE PF00437.20 KXH42483.1 - 0.00025 20.2 0.1 0.6 9.1 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_18 PF13238.6 KXH42483.1 - 0.00036 21.1 0.1 1.6 9.3 0.0 3.0 3 0 0 3 3 2 2 AAA domain DUF87 PF01935.17 KXH42483.1 - 0.00046 20.4 2.7 0.0083 16.2 0.1 2.5 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_25 PF13481.6 KXH42483.1 - 0.00066 19.3 0.9 0.22 11.1 0.1 2.7 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 KXH42483.1 - 0.00069 18.9 0.1 0.1 11.9 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_15 PF13175.6 KXH42483.1 - 0.00085 19.1 0.0 0.52 10.0 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 KXH42483.1 - 0.0013 18.7 1.4 0.88 9.5 0.1 3.0 3 0 0 3 3 2 1 NACHT domain FtsK_SpoIIIE PF01580.18 KXH42483.1 - 0.0026 17.2 1.4 0.22 10.9 0.1 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family Adeno_IVa2 PF02456.15 KXH42483.1 - 0.0037 16.1 0.3 1.1 8.0 0.1 2.9 3 0 0 3 3 3 1 Adenovirus IVa2 protein NB-ARC PF00931.22 KXH42483.1 - 0.0056 15.9 0.1 1.7 7.8 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain IstB_IS21 PF01695.17 KXH42483.1 - 0.0079 15.9 0.7 7.2 6.3 0.0 3.9 4 0 0 4 4 4 0 IstB-like ATP binding protein AAA_7 PF12775.7 KXH42483.1 - 0.008 15.7 0.1 5.1 6.6 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA PF00004.29 KXH42483.1 - 0.011 16.2 0.0 2.1 8.8 0.0 3.1 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) Roc PF08477.13 KXH42483.1 - 0.011 15.9 0.1 3.6 7.8 0.0 3.0 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase DUF815 PF05673.13 KXH42483.1 - 0.012 14.8 0.1 1.6 7.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) GTP_EFTU PF00009.27 KXH42483.1 - 0.012 15.1 0.0 1.8 8.1 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_24 PF13479.6 KXH42483.1 - 0.02 14.7 0.0 2.3 7.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 KXH42483.1 - 0.02 15.1 0.2 5.5 7.3 0.0 2.8 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_14 PF13173.6 KXH42483.1 - 0.022 14.8 0.0 1.9 8.5 0.0 2.8 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KXH42483.1 - 0.05 14.0 0.1 17 5.9 0.0 2.8 3 0 0 3 3 2 0 RNA helicase Rad17 PF03215.15 KXH42483.1 - 0.057 13.3 0.1 3.1 7.7 0.1 2.5 2 0 0 2 2 2 0 Rad17 P-loop domain G-alpha PF00503.20 KXH42483.1 - 0.059 12.5 0.0 5.3 6.1 0.0 2.7 3 0 0 3 3 3 0 G-protein alpha subunit AAA_5 PF07728.14 KXH42483.1 - 0.077 13.0 1.1 3.5 7.6 0.0 2.8 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.15 KXH42483.1 - 0.08 12.9 0.7 7.2 6.5 0.0 2.5 2 0 0 2 2 2 0 NTPase PduV-EutP PF10662.9 KXH42483.1 - 0.081 12.7 0.1 2.6 7.8 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ATPase_2 PF01637.18 KXH42483.1 - 0.11 12.4 0.0 4.5 7.1 0.0 2.6 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea TsaE PF02367.17 KXH42483.1 - 0.11 12.5 0.1 2.2 8.3 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATP_bind_1 PF03029.17 KXH42483.1 - 0.16 11.8 0.3 6.1 6.5 0.1 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DEAD PF00270.29 KXH42483.1 - 0.17 11.6 0.3 4.8 6.9 0.0 2.8 3 0 0 3 3 3 0 DEAD/DEAH box helicase AAA_28 PF13521.6 KXH42483.1 - 0.97 9.7 3.2 18 5.5 0.4 2.4 2 0 0 2 2 2 0 AAA domain DUF3632 PF12311.8 KXH42484.1 - 1.8e-36 126.2 3.1 2.7e-36 125.6 3.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) DUF4455 PF14643.6 KXH42484.1 - 0.057 12.1 0.0 0.081 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4455) Ribonuclease PF00545.20 KXH42485.1 - 5.8e-09 36.6 0.1 8.9e-09 36.0 0.1 1.3 1 0 0 1 1 1 1 ribonuclease HET PF06985.11 KXH42486.1 - 5.7e-25 88.4 0.3 1e-24 87.5 0.3 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Glyco_hydro_43 PF04616.14 KXH42488.1 - 4.4e-14 52.5 0.8 7.8e-14 51.7 0.8 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 CBM_35 PF16990.5 KXH42488.1 - 4.1e-06 27.1 0.4 9.6e-06 25.9 0.4 1.6 1 0 0 1 1 1 1 Carbohydrate binding module (family 35) Trypan_PARP PF05887.11 KXH42489.1 - 0.00025 21.1 18.6 0.00025 21.1 18.6 2.1 2 1 0 2 2 2 1 Procyclic acidic repetitive protein (PARP) BTB PF00651.31 KXH42489.1 - 0.0033 17.6 0.0 0.0066 16.7 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain FAD_binding_3 PF01494.19 KXH42490.1 - 5.3e-72 243.0 0.0 6.9e-72 242.6 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KXH42490.1 - 3.9e-06 26.3 0.1 2e-05 24.0 0.1 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXH42490.1 - 1.3e-05 24.9 0.1 0.0011 18.7 0.2 2.2 1 1 1 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KXH42490.1 - 0.0002 20.5 0.4 0.042 12.9 0.0 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KXH42490.1 - 0.00074 18.9 0.1 0.0047 16.2 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXH42490.1 - 0.0014 18.8 0.0 0.0038 17.4 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KXH42490.1 - 0.0014 18.6 0.0 0.0028 17.7 0.0 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding Thi4 PF01946.17 KXH42490.1 - 0.0015 17.8 0.1 0.0027 17.0 0.1 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 KXH42490.1 - 0.0041 16.3 0.0 0.0061 15.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 KXH42490.1 - 0.0065 17.0 0.3 0.057 14.0 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXH42490.1 - 0.0075 15.0 0.4 0.044 12.5 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein TrkA_N PF02254.18 KXH42490.1 - 0.045 14.0 0.1 0.1 12.9 0.0 1.6 2 0 0 2 2 2 0 TrkA-N domain Aminotran_3 PF00202.21 KXH42491.1 - 1.2e-90 304.1 0.0 1.4e-90 303.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 KXH42491.1 - 0.041 13.1 0.0 0.078 12.1 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II NAD_binding_6 PF08030.12 KXH42494.1 - 3.3e-31 108.5 0.0 6.6e-31 107.5 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KXH42494.1 - 1.6e-19 70.0 1.2 3.6e-19 68.9 0.0 2.2 2 0 0 2 2 2 1 FAD-binding domain Ferric_reduct PF01794.19 KXH42494.1 - 3.9e-17 62.5 12.3 3.9e-17 62.5 12.3 2.4 1 1 1 2 2 2 1 Ferric reductase like transmembrane component Metallophos_2 PF12850.7 KXH42495.1 - 7.4e-11 42.5 0.0 1e-08 35.5 0.0 2.6 1 1 1 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 KXH42495.1 - 8.4e-10 39.5 0.0 1.8e-09 38.4 0.0 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase LRR_4 PF12799.7 KXH42497.1 - 0.24 11.9 8.8 6.6 7.3 0.1 4.5 5 1 1 6 6 6 0 Leucine Rich repeats (2 copies) SKG6 PF08693.10 KXH42498.1 - 0.00036 19.9 0.4 0.0012 18.2 0.4 1.9 1 0 0 1 1 1 1 Transmembrane alpha-helix domain VSP PF03302.13 KXH42498.1 - 0.0055 15.6 6.6 0.0055 15.6 6.6 1.9 2 0 0 2 2 2 1 Giardia variant-specific surface protein MLANA PF14991.6 KXH42498.1 - 0.0074 16.6 0.0 0.016 15.4 0.0 1.5 1 0 0 1 1 1 1 Protein melan-A Gram_pos_anchor PF00746.21 KXH42498.1 - 0.027 14.4 0.3 0.027 14.4 0.3 4.1 3 1 1 4 4 4 0 LPXTG cell wall anchor motif MFS_1 PF07690.16 KXH42499.1 - 2.3e-30 105.7 30.0 2.3e-30 105.7 30.0 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF2649 PF10854.8 KXH42499.1 - 0.069 13.5 1.2 0.38 11.1 1.2 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2649) AAA PF00004.29 KXH42504.1 - 2.2e-17 63.7 0.0 4.5e-17 62.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Fungal_trans PF04082.18 KXH42505.1 - 2.4e-21 76.0 0.9 3.9e-21 75.3 0.9 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH42505.1 - 0.0028 17.7 8.8 0.0052 16.9 8.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Transp_cyt_pur PF02133.15 KXH42506.1 - 2.6e-77 260.5 26.6 4.6e-73 246.5 21.5 2.0 1 1 1 2 2 2 2 Permease for cytosine/purines, uracil, thiamine, allantoin DUF917 PF06032.12 KXH42507.1 - 1.3e-114 382.7 0.0 2.3e-114 381.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF917) Hydant_A_N PF05378.13 KXH42507.1 - 1e-29 103.5 2.7 4.7e-26 91.6 0.2 3.5 3 1 0 3 3 3 2 Hydantoinase/oxoprolinase N-terminal region Hydantoinase_A PF01968.18 KXH42507.1 - 6.1e-21 74.9 13.5 1.7e-18 66.9 2.2 4.2 2 1 1 3 3 3 2 Hydantoinase/oxoprolinase MutL PF13941.6 KXH42507.1 - 5e-06 25.4 2.4 0.024 13.2 0.0 2.5 2 0 0 2 2 2 2 MutL protein StbA PF06406.11 KXH42507.1 - 0.00028 20.2 0.1 0.19 10.9 0.0 2.4 2 0 0 2 2 2 2 StbA protein ROK PF00480.20 KXH42507.1 - 0.0087 15.6 0.4 0.028 13.9 0.4 1.9 1 0 0 1 1 1 1 ROK family CM_1 PF07736.11 KXH42507.1 - 0.038 14.4 0.0 3.8 7.9 0.1 2.7 2 0 0 2 2 2 0 Chorismate mutase type I DUF3663 PF12404.8 KXH42507.1 - 0.076 13.1 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 Peptidase FtsA PF14450.6 KXH42507.1 - 0.28 11.6 4.5 9.6 6.7 0.1 3.7 2 1 0 2 2 2 0 Cell division protein FtsA BcrAD_BadFG PF01869.20 KXH42507.1 - 0.45 9.9 7.7 0.4 10.1 0.9 2.5 2 1 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family CNDH2_M PF16869.5 KXH42509.1 - 0.0086 16.8 3.5 0.017 15.8 3.5 1.4 1 0 0 1 1 1 1 PF16858 F-box PF00646.33 KXH42509.1 - 0.033 14.1 0.1 0.088 12.7 0.1 1.7 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.7 KXH42509.1 - 0.08 12.8 0.2 0.24 11.3 0.2 1.8 1 0 0 1 1 1 0 F-box-like adh_short PF00106.25 KXH42511.1 - 6.8e-22 77.9 0.0 7e-18 64.8 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXH42511.1 - 5.5e-11 42.5 0.0 2.6e-10 40.2 0.0 1.8 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH42511.1 - 1.4e-05 25.1 0.1 2.1e-05 24.5 0.1 1.2 1 0 0 1 1 1 1 KR domain Cofilin_ADF PF00241.20 KXH42512.1 - 6.5e-24 84.0 0.1 7.3e-24 83.9 0.1 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein DUF3656 PF12392.8 KXH42512.1 - 0.12 13.0 0.0 0.17 12.5 0.0 1.3 1 0 0 1 1 1 0 Collagenase DUF4523 PF15023.6 KXH42516.1 - 0.077 12.8 1.1 0.17 11.7 1.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4523) Cep57_MT_bd PF06657.13 KXH42516.1 - 0.2 12.1 1.6 4.9 7.7 0.3 2.3 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Nore1-SARAH PF16517.5 KXH42516.1 - 4 7.4 7.6 2.7 8.0 2.3 2.4 1 1 1 2 2 2 0 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain HSP70 PF00012.20 KXH42517.1 - 0.0069 14.6 0.0 0.012 13.8 0.0 1.3 1 0 0 1 1 1 1 Hsp70 protein MFS_1 PF07690.16 KXH42518.1 - 1.8e-43 148.9 26.7 1.8e-43 148.9 26.7 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH42518.1 - 1.1e-13 50.9 8.0 1.1e-13 50.9 8.0 2.6 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 KXH42518.1 - 6.7e-10 38.0 2.2 1.1e-09 37.3 2.2 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 KXH42521.1 - 4.6e-29 101.5 28.2 6.8e-29 100.9 28.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Trp_oprn_chp PF09534.10 KXH42521.1 - 0.36 10.6 0.0 0.36 10.6 0.0 2.8 4 0 0 4 4 4 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) p450 PF00067.22 KXH42522.1 - 1.5e-63 215.2 0.0 1.9e-63 214.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Band_7 PF01145.25 KXH42523.1 - 2.9e-14 53.5 0.4 2.9e-14 53.5 0.4 3.5 3 2 0 3 3 3 1 SPFH domain / Band 7 family DUF3093 PF11292.8 KXH42523.1 - 0.27 11.5 1.1 0.78 10.0 1.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3093) CFEM PF05730.11 KXH42524.1 - 2.4e-14 53.1 9.6 3.4e-14 52.7 9.6 1.2 1 0 0 1 1 1 1 CFEM domain DAO PF01266.24 KXH42525.1 - 4.6e-34 118.6 0.1 6.2e-34 118.1 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXH42525.1 - 8.1e-07 29.2 0.0 2.1e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXH42525.1 - 2.8e-05 23.5 0.1 0.017 14.4 0.0 2.9 3 1 1 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXH42525.1 - 9.7e-05 21.6 0.1 0.015 14.4 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.6 KXH42525.1 - 0.00016 21.0 0.0 0.0015 17.9 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KXH42525.1 - 0.0022 17.1 0.0 1.8 7.6 0.0 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Shikimate_DH PF01488.20 KXH42525.1 - 0.0024 17.9 0.0 0.0052 16.8 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 KXH42525.1 - 0.0033 18.0 0.0 0.26 11.9 0.0 2.8 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXH42525.1 - 0.0038 16.0 0.0 2.2 6.9 0.0 2.4 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_3 PF01494.19 KXH42525.1 - 0.0039 16.5 0.0 0.0069 15.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Glu_dehyd_C PF16912.5 KXH42525.1 - 0.046 13.2 0.0 0.14 11.6 0.0 1.7 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus NAD_binding_9 PF13454.6 KXH42525.1 - 0.099 12.6 0.0 0.47 10.4 0.0 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding GMC_oxred_N PF00732.19 KXH42525.1 - 0.11 11.9 0.0 13 5.0 0.0 2.6 2 1 0 2 2 2 0 GMC oxidoreductase ApbA PF02558.16 KXH42525.1 - 0.15 11.7 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.18 KXH42525.1 - 0.16 12.3 0.0 0.4 11.0 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain Sugar_tr PF00083.24 KXH42526.1 - 1.6e-66 225.1 23.7 2e-66 224.7 23.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH42526.1 - 1.7e-20 73.2 40.1 9.2e-16 57.7 22.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily YMF19 PF02326.15 KXH42526.1 - 1.1 10.1 4.7 2.2 9.1 0.0 2.7 2 0 0 2 2 2 0 Plant ATP synthase F0 DUF3267 PF11667.8 KXH42526.1 - 2 8.7 10.6 1.1 9.6 4.9 3.1 2 0 0 2 2 2 0 Putative zincin peptidase Comm PF15957.5 KXH42526.1 - 6.4 7.1 5.6 7.6 6.9 3.3 2.2 2 0 0 2 2 2 0 Commissureless 2-Hacid_dh_C PF02826.19 KXH42527.1 - 1.1e-53 181.2 0.0 1.5e-53 180.8 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KXH42527.1 - 1.8e-18 66.5 0.0 2.3e-18 66.1 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KXH42527.1 - 0.00032 20.9 0.0 0.00065 19.9 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase HypF_C PF17788.1 KXH42527.1 - 0.015 16.0 0.0 0.031 15.0 0.0 1.5 1 0 0 1 1 1 0 HypF Kae1-like domain EHD_N PF16880.5 KXH42527.1 - 0.16 11.9 0.1 0.32 10.9 0.1 1.5 1 0 0 1 1 1 0 N-terminal EH-domain containing protein Amidohydro_2 PF04909.14 KXH42528.1 - 0.035 13.9 0.0 0.18 11.5 0.0 1.9 1 1 0 1 1 1 0 Amidohydrolase Aldolase_II PF00596.21 KXH42529.1 - 2.7e-48 164.4 0.0 3.3e-48 164.1 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain DUF1338 PF07063.13 KXH42530.1 - 5.5e-109 364.3 0.0 6.7e-109 364.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1338) ApbA_C PF08546.11 KXH42530.1 - 0.1 12.8 0.0 0.45 10.7 0.0 2.0 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA C terminal Fungal_trans PF04082.18 KXH42531.1 - 9.5e-30 103.5 0.0 1.8e-29 102.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH42531.1 - 1.1e-07 31.9 6.5 2.3e-07 30.8 6.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_71 PF03659.14 KXH42532.1 - 7.6e-132 439.7 0.2 1.2e-131 439.0 0.0 1.4 2 0 0 2 2 2 1 Glycosyl hydrolase family 71 DOCK_N PF16172.5 KXH42533.1 - 9.3e-125 416.5 0.0 1.5e-124 415.8 0.0 1.3 1 0 0 1 1 1 1 DOCK N-terminus DOCK-C2 PF14429.6 KXH42533.1 - 1.7e-37 129.1 0.0 3.6e-37 128.1 0.0 1.6 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins DHR-2 PF06920.13 KXH42533.1 - 3.8e-32 111.6 4.2 6.3e-31 107.6 4.2 2.5 1 1 0 1 1 1 1 Dock homology region 2 SH3_1 PF00018.28 KXH42533.1 - 0.00011 21.7 0.0 0.00026 20.5 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KXH42533.1 - 0.0045 16.8 0.0 0.024 14.5 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 KXH42533.1 - 0.041 13.6 0.0 0.26 11.0 0.0 2.3 2 0 0 2 2 2 0 Variant SH3 domain PAP2_3 PF14378.6 KXH42534.1 - 4.6e-36 124.3 10.5 1.1e-27 97.0 3.2 2.4 2 0 0 2 2 2 2 PAP2 superfamily PAP2 PF01569.21 KXH42534.1 - 0.0062 16.3 2.8 0.0062 16.3 2.8 2.6 2 1 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.6 KXH42534.1 - 0.38 11.3 3.7 0.91 10.1 0.1 2.6 2 0 0 2 2 2 0 PAP2 superfamily C-terminal Glyco_hydro_88 PF07470.13 KXH42535.1 - 7.5e-64 216.0 2.5 9.8e-64 215.6 2.5 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 MFS_1 PF07690.16 KXH42536.1 - 4.3e-46 157.5 31.9 4.3e-46 157.5 31.9 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH42536.1 - 6.3e-15 55.0 2.5 1.2e-14 54.1 2.5 1.4 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 KXH42536.1 - 5.4e-07 28.4 2.8 7.3e-07 28.0 2.8 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Fungal_trans PF04082.18 KXH42537.1 - 1.2e-10 40.9 0.0 1.9e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Aminotran_5 PF00266.19 KXH42538.1 - 2.9e-30 105.5 0.0 5.1e-21 75.1 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-V Lactamase_B PF00753.27 KXH42539.1 - 1e-23 84.4 4.1 1.3e-23 84.1 4.1 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KXH42539.1 - 7.4e-05 22.4 0.1 0.00011 21.8 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain AMP-binding PF00501.28 KXH42540.1 - 5.8e-78 262.4 0.0 8.4e-78 261.8 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 KXH42540.1 - 1.5e-47 162.3 0.0 2e-47 161.9 0.0 1.1 1 0 0 1 1 1 1 Condensation domain NAD_binding_4 PF07993.12 KXH42540.1 - 5.9e-20 71.5 0.0 7.1e-19 68.0 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein PP-binding PF00550.25 KXH42540.1 - 1.4e-06 28.5 0.3 3.3e-06 27.3 0.3 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KXH42540.1 - 1.9e-05 25.6 0.5 0.00023 22.1 0.1 2.7 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain Epimerase PF01370.21 KXH42540.1 - 0.00022 20.8 0.0 0.00042 19.8 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXH42540.1 - 0.066 12.2 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family p450 PF00067.22 KXH42541.1 - 1e-67 228.9 0.0 1.3e-67 228.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Epimerase PF01370.21 KXH42542.1 - 9.2e-23 80.9 0.0 2.3e-22 79.7 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXH42542.1 - 8.6e-19 68.1 0.3 3.1e-13 49.8 0.0 3.0 2 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KXH42542.1 - 7.3e-09 35.2 0.6 3.3e-06 26.5 0.1 3.0 2 1 1 3 3 3 2 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 KXH42542.1 - 9.8e-09 34.7 0.0 6e-08 32.2 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein RmlD_sub_bind PF04321.17 KXH42542.1 - 6.7e-08 32.0 0.0 1.3e-07 31.0 0.0 1.6 1 1 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 KXH42542.1 - 0.0038 16.3 0.0 0.0096 14.9 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 KXH42542.1 - 0.2 11.5 0.8 12 5.8 0.1 2.5 2 0 0 2 2 2 0 KR domain FSH1 PF03959.13 KXH42543.1 - 2.4e-29 102.5 0.0 3.1e-29 102.2 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.13 KXH42543.1 - 0.0046 16.8 0.1 0.0075 16.1 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 KXH42543.1 - 0.028 14.2 0.2 0.1 12.4 0.0 1.9 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Ysc84 PF04366.12 KXH42544.1 - 6e-51 171.5 0.0 9.4e-51 170.9 0.0 1.3 1 0 0 1 1 1 1 Las17-binding protein actin regulator DUF604 PF04646.12 KXH42546.1 - 1.9e-09 37.3 0.0 5.4e-07 29.3 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function, DUF604 Fringe PF02434.16 KXH42546.1 - 3.7e-06 26.6 0.0 7.3e-06 25.6 0.0 1.5 1 1 0 1 1 1 1 Fringe-like BRO1 PF03097.18 KXH42547.1 - 2e-121 405.5 0.0 2.9e-121 404.9 0.0 1.2 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 KXH42547.1 - 1.1e-84 284.3 3.8 1.1e-84 284.3 3.8 1.8 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV UPF0242 PF06785.11 KXH42547.1 - 0.64 10.1 6.6 7.9 6.5 4.4 2.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus FAA_hydrolase PF01557.18 KXH42548.1 - 1.2e-64 218.0 0.0 1.7e-64 217.5 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Hydrolase_4 PF12146.8 KXH42548.1 - 3.5e-19 69.0 0.0 1e-18 67.5 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KXH42548.1 - 6.5e-19 68.6 0.2 1.7e-11 44.3 0.1 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXH42548.1 - 3.5e-18 67.0 0.5 6.2e-18 66.2 0.5 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.13 KXH42548.1 - 6.5e-09 35.9 2.2 0.00049 20.0 0.1 2.9 2 1 1 3 3 3 2 Serine hydrolase Abhydrolase_4 PF08386.10 KXH42548.1 - 0.072 13.2 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 TAP-like protein p450 PF00067.22 KXH42549.1 - 1.5e-57 195.3 0.0 1.9e-57 195.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_3 PF01494.19 KXH42550.1 - 1.5e-26 93.5 0.0 4.8e-26 91.8 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KXH42550.1 - 1.4e-06 27.8 0.5 0.00038 19.8 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KXH42550.1 - 2.5e-05 23.5 0.5 0.0004 19.5 0.5 2.1 1 1 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KXH42550.1 - 0.00014 21.2 0.6 0.003 16.9 0.2 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXH42550.1 - 0.00033 20.4 0.0 0.00055 19.6 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXH42550.1 - 0.0018 18.5 0.4 0.0048 17.1 0.4 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KXH42550.1 - 0.007 16.9 1.6 0.012 16.1 0.5 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KXH42550.1 - 0.011 15.1 0.3 1.1 8.5 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 KXH42550.1 - 0.028 13.5 1.1 0.091 11.8 0.5 2.0 2 0 0 2 2 2 0 FAD binding domain GIDA PF01134.22 KXH42550.1 - 0.035 13.2 0.1 0.075 12.1 0.1 1.6 1 1 0 1 1 1 0 Glucose inhibited division protein A Trp_halogenase PF04820.14 KXH42550.1 - 0.047 12.5 0.6 0.23 10.2 0.2 2.0 2 0 0 2 2 2 0 Tryptophan halogenase SIR2 PF02146.17 KXH42552.1 - 2.8e-57 193.5 0.0 4.1e-57 192.9 0.0 1.3 1 0 0 1 1 1 1 Sir2 family MFS_1 PF07690.16 KXH42552.1 - 1.6e-14 53.7 25.9 1.6e-14 53.7 25.9 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily FapA PF03961.13 KXH42552.1 - 0.025 13.2 0.5 0.045 12.4 0.5 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF3464 PF11947.8 KXH42552.1 - 2 8.2 4.5 3.8 7.2 0.1 2.8 3 0 0 3 3 3 0 Photosynthesis affected mutant 68 NUDIX PF00293.28 KXH42553.1 - 1.1e-15 57.8 0.1 1.8e-15 57.1 0.1 1.3 1 0 0 1 1 1 1 NUDIX domain NUDIX PF00293.28 KXH42554.1 - 1.4e-07 31.6 0.0 2.4e-07 30.9 0.0 1.4 1 1 0 1 1 1 1 NUDIX domain Abhydrolase_1 PF00561.20 KXH42555.1 - 9.7e-46 156.5 0.0 3.9e-45 154.5 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 KXH42555.1 - 0.0017 18.0 0.0 0.0029 17.3 0.0 1.3 1 0 0 1 1 1 1 Putative esterase zf-RING_6 PF14835.6 KXH42555.1 - 0.091 12.6 0.1 0.23 11.4 0.1 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Cupin_2 PF07883.11 KXH42557.1 - 4.9e-11 42.2 0.8 6.8e-11 41.7 0.8 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 KXH42557.1 - 9.8e-05 22.0 0.7 0.00014 21.5 0.7 1.3 1 1 0 1 1 1 1 Cupin Cupin_7 PF12973.7 KXH42557.1 - 0.051 13.5 0.1 0.072 13.0 0.1 1.4 1 1 0 1 1 1 0 ChrR Cupin-like domain ADH_zinc_N_2 PF13602.6 KXH42558.1 - 3e-16 60.7 0.0 4.7e-16 60.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KXH42558.1 - 3.5e-09 36.7 0.1 8.6e-09 35.5 0.1 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXH42558.1 - 8.9e-07 28.8 0.0 1.8e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Semialdhyde_dh PF01118.24 KXH42558.1 - 0.0047 17.3 0.3 0.011 16.2 0.3 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 KXH42558.1 - 0.02 15.0 0.6 0.036 14.2 0.6 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Fungal_trans PF04082.18 KXH42559.1 - 3.1e-10 39.6 0.1 5.3e-10 38.8 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH42559.1 - 2e-09 37.4 8.8 3.7e-09 36.6 8.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldedh PF00171.22 KXH42559.1 - 0.021 13.3 0.0 0.031 12.8 0.0 1.1 1 0 0 1 1 1 0 Aldehyde dehydrogenase family Pyr_redox_2 PF07992.14 KXH42560.1 - 2e-29 102.8 0.0 2.1e-27 96.1 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXH42560.1 - 6.1e-05 23.1 0.1 0.44 10.5 0.0 3.5 2 2 1 3 3 3 2 FAD-NAD(P)-binding Pyr_redox PF00070.27 KXH42560.1 - 0.00094 19.7 0.0 1.1 9.9 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXH42560.1 - 0.0013 18.4 0.7 0.1 12.2 0.2 2.6 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KXH42560.1 - 0.18 11.0 0.1 20 4.3 0.1 3.0 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Abhydrolase_6 PF12697.7 KXH42561.1 - 2.4e-11 44.7 0.0 2.9e-11 44.4 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXH42561.1 - 0.0062 16.2 0.0 0.45 10.1 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Ank_4 PF13637.6 KXH42563.1 - 2.7e-64 212.7 16.9 9.5e-08 32.4 0.0 9.9 1 1 11 12 12 12 12 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXH42563.1 - 9.9e-62 205.5 11.2 8.2e-14 52.0 0.2 5.9 4 3 1 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXH42563.1 - 9e-42 140.6 16.1 3.9e-07 30.2 0.1 11.2 3 2 9 12 12 12 11 Ankyrin repeats (many copies) Ank PF00023.30 KXH42563.1 - 3e-41 138.1 16.6 0.0014 18.9 0.1 12.4 12 0 0 12 12 12 11 Ankyrin repeat Ank_3 PF13606.6 KXH42563.1 - 1.3e-38 126.6 12.0 0.058 14.0 0.0 12.8 13 0 0 13 13 13 11 Ankyrin repeat adh_short_C2 PF13561.6 KXH42563.1 - 3.7e-09 36.5 0.0 1.2e-08 34.8 0.0 1.9 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF3447 PF11929.8 KXH42563.1 - 0.00045 20.1 0.0 22 5.1 0.0 5.5 5 2 1 6 6 6 1 Domain of unknown function (DUF3447) NPP1 PF05630.11 KXH42564.1 - 2.9e-39 135.2 0.0 3.8e-39 134.8 0.0 1.1 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) ArfGap PF01412.18 KXH42567.1 - 1.9e-32 111.7 0.2 9.4e-32 109.5 0.0 2.3 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf BAR_3 PF16746.5 KXH42567.1 - 3.8e-24 85.7 14.9 6e-24 85.1 14.9 1.2 1 0 0 1 1 1 1 BAR domain of APPL family PH PF00169.29 KXH42567.1 - 9.3e-13 48.6 0.4 2.7e-12 47.1 0.4 1.9 1 0 0 1 1 1 1 PH domain EMP24_GP25L PF01105.24 KXH42567.1 - 0.093 12.7 4.0 0.68 9.9 1.8 2.5 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD tRNA-synt_2 PF00152.20 KXH42567.1 - 0.22 10.5 8.1 0.36 9.8 8.1 1.2 1 0 0 1 1 1 0 tRNA synthetases class II (D, K and N) ANAPC9 PF12856.7 KXH42567.1 - 0.4 10.9 4.3 0.95 9.7 4.3 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 9 PH_9 PF15410.6 KXH42567.1 - 0.7 10.3 4.5 1.5 9.2 1.1 3.0 2 1 0 2 2 2 0 Pleckstrin homology domain FTO_CTD PF12934.7 KXH42567.1 - 0.96 9.2 3.8 0.81 9.4 0.2 2.3 2 0 0 2 2 2 0 FTO C-terminal domain BAR PF03114.18 KXH42567.1 - 2 8.0 16.3 0.41 10.3 12.6 1.7 1 1 0 1 1 1 0 BAR domain ATP-synt_E PF05680.12 KXH42567.1 - 5.7 7.4 12.4 0.21 12.0 0.3 2.8 3 0 0 3 3 3 0 ATP synthase E chain FHA PF00498.26 KXH42569.1 - 2.5e-08 34.1 0.0 6.3e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KXH42569.1 - 1.8e-05 25.0 0.0 3.4e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Pkinase PF00069.25 KXH42569.1 - 0.00045 19.7 0.0 0.00065 19.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain PCI PF01399.27 KXH42570.1 - 3.1e-14 53.4 0.4 1.4e-13 51.2 0.1 2.3 3 0 0 3 3 3 1 PCI domain eIF3m_C_helix PF18005.1 KXH42570.1 - 2.1e-12 46.5 0.5 4e-12 45.6 0.5 1.5 1 0 0 1 1 1 1 eIF3 subunit M, C-terminal helix ADK PF00406.22 KXH42571.1 - 1.2e-45 155.3 0.0 1.5e-45 155.0 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KXH42571.1 - 2.2e-35 122.0 0.0 3e-35 121.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KXH42571.1 - 0.00011 22.8 0.0 0.00019 22.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KXH42571.1 - 0.00013 22.1 0.0 0.00026 21.1 0.0 1.5 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 KXH42571.1 - 0.0079 15.9 0.0 2.9 7.5 0.0 2.2 2 0 0 2 2 2 2 Thymidylate kinase Cys_Met_Meta_PP PF01053.20 KXH42572.1 - 4.8e-26 91.2 0.0 7.7e-26 90.5 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KXH42572.1 - 0.00075 18.8 0.0 0.0013 18.0 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Methyltransf_23 PF13489.6 KXH42573.1 - 9.4e-19 67.8 0.0 1.3e-18 67.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH42573.1 - 2.1e-08 34.7 0.0 4.2e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH42573.1 - 3.3e-08 33.5 0.0 2.3e-07 30.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH42573.1 - 1.1e-05 26.0 0.0 6.4e-05 23.6 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH42573.1 - 2e-05 25.2 0.0 3.3e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 KXH42573.1 - 0.0042 16.4 0.0 0.17 11.1 0.0 2.7 2 1 0 2 2 2 1 O-methyltransferase domain MTS PF05175.14 KXH42573.1 - 0.011 15.3 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Ubie_methyltran PF01209.18 KXH42573.1 - 0.026 13.8 0.0 6.2 6.1 0.0 2.6 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 KXH42573.1 - 0.046 13.2 0.0 0.084 12.3 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase CMAS PF02353.20 KXH42573.1 - 0.14 11.4 0.0 0.36 10.1 0.0 1.6 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase MCM PF00493.23 KXH42574.1 - 1.4e-100 335.0 0.0 2.1e-100 334.5 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KXH42574.1 - 4.1e-39 133.3 0.6 7.6e-39 132.4 0.6 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KXH42574.1 - 1.1e-27 96.3 4.9 2.9e-27 94.9 4.9 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KXH42574.1 - 9.4e-16 58.3 0.1 3.6e-15 56.4 0.0 2.0 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 KXH42574.1 - 2.3e-05 23.9 0.0 0.00043 19.7 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KXH42574.1 - 5.7e-05 23.1 0.1 0.0003 20.8 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KXH42574.1 - 0.0012 18.7 0.0 0.0046 16.8 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KXH42574.1 - 0.13 12.0 0.2 2.6 7.7 0.0 2.7 3 0 0 3 3 3 0 Sigma-54 interaction domain Clat_adaptor_s PF01217.20 KXH42575.1 - 3.9e-17 62.5 1.3 1.8e-16 60.4 1.3 1.8 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Sua5_yciO_yrdC PF01300.18 KXH42576.1 - 2.1e-53 180.5 0.0 3.3e-53 179.8 0.0 1.3 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.13 KXH42576.1 - 1.3e-29 103.4 0.0 2.2e-29 102.7 0.0 1.4 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding SLD5_C PF16922.5 KXH42577.1 - 6.2e-14 51.9 0.0 1e-13 51.2 0.0 1.4 1 0 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus Sld5 PF05916.11 KXH42577.1 - 2.4e-06 27.9 0.1 7.9e-06 26.3 0.0 1.8 2 0 0 2 2 2 1 GINS complex protein FMN_dh PF01070.18 KXH42578.1 - 3.5e-118 394.6 0.0 4e-118 394.4 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 KXH42578.1 - 1.6e-05 24.2 0.3 2.5e-05 23.6 0.3 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 KXH42578.1 - 0.00015 20.9 1.0 0.00052 19.1 0.6 1.8 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 KXH42578.1 - 0.00062 19.2 1.4 0.00097 18.6 1.4 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase ThiG PF05690.14 KXH42578.1 - 0.002 17.5 0.6 0.13 11.5 0.7 2.6 3 0 0 3 3 3 1 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 KXH42578.1 - 0.012 15.1 0.5 0.043 13.3 0.4 1.8 1 1 1 2 2 2 0 Histidine biosynthesis protein Ferritin_2 PF13668.6 KXH42579.1 - 2.9e-44 150.6 0.2 4.7e-44 149.9 0.2 1.3 1 0 0 1 1 1 1 Ferritin-like domain YoaP PF14268.6 KXH42579.1 - 0.12 11.8 0.1 0.29 10.7 0.1 1.6 1 0 0 1 1 1 0 YoaP-like Lipase_GDSL_2 PF13472.6 KXH42580.1 - 4.6e-24 85.8 3.0 8.4e-24 84.9 3.0 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KXH42580.1 - 8.3e-11 42.2 0.0 1.4e-10 41.5 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase VWA_3 PF13768.6 KXH42580.1 - 0.022 14.7 0.0 0.066 13.1 0.0 1.8 2 0 0 2 2 2 0 von Willebrand factor type A domain DUF3336 PF11815.8 KXH42582.1 - 8.4e-36 122.7 0.0 2.3e-34 118.1 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3336) Patatin PF01734.22 KXH42582.1 - 7.7e-13 49.1 1.1 1.5e-12 48.2 0.1 2.0 2 0 0 2 2 2 1 Patatin-like phospholipase Leo1 PF04004.13 KXH42583.1 - 1.8e-34 119.0 0.0 3.1e-34 118.2 0.0 1.4 1 0 0 1 1 1 1 Leo1-like protein Mob1_phocein PF03637.17 KXH42584.1 - 5.6e-43 146.9 0.0 1.2e-42 145.8 0.0 1.5 1 1 0 1 1 1 1 Mob1/phocein family TauD PF02668.16 KXH42661.1 - 1.7e-43 149.4 0.0 2.3e-43 148.9 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Ax_dynein_light PF10211.9 KXH42661.1 - 0.01 15.8 0.0 0.11 12.4 0.0 2.0 2 0 0 2 2 2 1 Axonemal dynein light chain UL16 PF17622.2 KXH42661.1 - 0.04 13.6 0.0 0.065 12.9 0.0 1.3 1 0 0 1 1 1 0 Viral unique long protein 16 MFS_1 PF07690.16 KXH42662.1 - 3.6e-18 65.6 15.5 5e-18 65.2 15.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Abhydrolase_1 PF00561.20 KXH42663.1 - 4.5e-18 65.8 0.0 6.3e-18 65.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXH42663.1 - 1.3e-15 58.7 3.4 1.7e-15 58.3 3.4 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXH42663.1 - 1.8e-07 30.7 0.0 2.9e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 KXH42663.1 - 0.0079 15.9 0.2 0.018 14.8 0.1 1.6 2 0 0 2 2 2 1 PGAP1-like protein Ser_hydrolase PF06821.13 KXH42663.1 - 0.075 12.9 0.1 0.18 11.7 0.1 1.6 1 0 0 1 1 1 0 Serine hydrolase Methyltransf_23 PF13489.6 KXH42664.1 - 2.9e-16 59.8 0.0 4.6e-16 59.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH42664.1 - 7.9e-07 29.7 0.0 3e-06 27.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH42664.1 - 6.7e-06 26.0 0.0 0.11 12.2 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 KXH42664.1 - 1.2e-05 25.9 0.0 2.2e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH42664.1 - 0.00012 22.7 0.0 0.0014 19.3 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain ketoacyl-synt PF00109.26 KXH42665.1 - 4.3e-65 219.8 0.0 1e-64 218.6 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.6 KXH42665.1 - 1e-59 202.2 0.0 1.4e-59 201.7 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 KXH42665.1 - 3.8e-59 199.6 0.5 1.4e-58 197.8 0.3 2.1 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.21 KXH42665.1 - 8.8e-51 173.3 0.2 1.4e-50 172.6 0.2 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KXH42665.1 - 9.1e-35 119.2 1.6 9.8e-35 119.1 0.1 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KXH42665.1 - 9.6e-24 84.0 0.0 2e-23 83.0 0.0 1.6 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_12 PF08242.12 KXH42665.1 - 1.8e-19 70.3 0.0 5e-19 68.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.26 KXH42665.1 - 9.7e-17 61.2 0.0 3.8e-16 59.2 0.0 2.1 2 0 0 2 2 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXH42665.1 - 1.9e-16 61.3 0.0 1.2e-15 58.7 0.0 2.4 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_31 PF13847.6 KXH42665.1 - 2.5e-12 46.8 0.0 6.7e-12 45.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH42665.1 - 3.2e-11 43.8 0.0 1.7e-10 41.5 0.0 2.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXH42665.1 - 1.4e-08 34.7 0.0 3e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH42665.1 - 1.4e-08 35.2 0.0 5.4e-08 33.4 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain adh_short PF00106.25 KXH42665.1 - 1.2e-06 28.1 1.3 2.1e-06 27.4 0.1 2.0 2 0 0 2 2 2 1 short chain dehydrogenase ADH_N PF08240.12 KXH42665.1 - 5.5e-05 23.0 0.3 0.00013 21.8 0.3 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain adh_short_C2 PF13561.6 KXH42665.1 - 0.00065 19.3 0.0 0.0014 18.2 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Ubie_methyltran PF01209.18 KXH42665.1 - 0.005 16.2 0.0 0.0095 15.3 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Thiolase_N PF00108.23 KXH42665.1 - 0.0062 15.9 0.1 0.04 13.3 0.1 2.1 2 0 0 2 2 2 1 Thiolase, N-terminal domain Methyltransf_28 PF02636.17 KXH42665.1 - 0.054 13.1 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_16 PF10294.9 KXH42665.1 - 0.084 12.6 0.0 0.29 10.8 0.0 1.9 1 1 0 1 1 1 0 Lysine methyltransferase SAT PF16073.5 KXH42665.1 - 0.12 12.1 0.4 1.7 8.3 0.1 2.4 2 0 0 2 2 2 0 Starter unit:ACP transacylase in aflatoxin biosynthesis Thioesterase PF00975.20 KXH42665.1 - 0.2 11.8 0.1 0.45 10.6 0.1 1.5 1 0 0 1 1 1 0 Thioesterase domain Oxidored_FMN PF00724.20 KXH42666.1 - 1.5e-63 215.1 0.0 2e-63 214.8 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.17 KXH42666.1 - 2.9e-05 23.3 0.0 7.2e-05 22.0 0.0 1.7 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 KXH42666.1 - 0.028 13.9 0.0 0.048 13.1 0.0 1.3 1 0 0 1 1 1 0 Histidine biosynthesis protein FMN_dh PF01070.18 KXH42666.1 - 0.053 12.5 4.3 0.028 13.5 2.1 1.5 2 0 0 2 2 2 0 FMN-dependent dehydrogenase DHO_dh PF01180.21 KXH42666.1 - 0.1 11.8 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase Zn_clus PF00172.18 KXH42667.1 - 2.8e-09 37.0 11.6 4.6e-09 36.3 11.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXH42667.1 - 0.0021 17.1 0.0 0.0035 16.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Spc29 PF17082.5 KXH42667.1 - 0.032 14.1 0.4 0.07 13.0 0.0 1.7 2 0 0 2 2 2 0 Spindle Pole Component 29 Trimer_CC PF08954.11 KXH42667.1 - 0.57 9.8 3.0 1.5 8.5 3.0 1.7 1 0 0 1 1 1 0 Trimerisation motif Sld5 PF05916.11 KXH42668.1 - 2e-31 108.7 0.0 4.3e-31 107.6 0.0 1.5 2 0 0 2 2 2 1 GINS complex protein DUF1445 PF07286.12 KXH42669.1 - 3.2e-62 208.7 0.1 4.4e-62 208.2 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1445) Imm72 PF15584.6 KXH42669.1 - 0.015 15.4 0.0 0.031 14.4 0.0 1.5 1 0 0 1 1 1 0 Immunity protein 72 Aldo_ket_red PF00248.21 KXH42670.1 - 1.2e-67 228.2 0.0 1.3e-67 228.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Rhomboid PF01694.22 KXH42671.1 - 0.012 15.7 7.4 0.049 13.6 5.2 2.7 1 1 0 1 1 1 0 Rhomboid family SNF2_N PF00176.23 KXH42672.1 - 4.7e-64 216.3 0.2 2.4e-63 214.0 0.1 2.0 1 1 1 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KXH42672.1 - 6.5e-23 81.2 0.0 2.8e-22 79.1 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXH42672.1 - 3.2e-08 33.7 0.5 1.9e-07 31.2 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KXH42672.1 - 0.00022 21.1 0.0 0.0008 19.2 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 KXH42672.1 - 0.00052 19.3 0.0 0.00052 19.3 0.0 2.0 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase SWI2_SNF2 PF18766.1 KXH42672.1 - 0.0066 16.1 0.8 0.012 15.3 0.0 1.9 2 0 0 2 2 2 1 SWI2/SNF2 ATPase tRNA_bind PF01588.20 KXH42673.1 - 2.8e-23 81.8 0.2 6.6e-23 80.7 0.2 1.7 1 0 0 1 1 1 1 Putative tRNA binding domain GST_C_2 PF13410.6 KXH42673.1 - 1.9e-05 24.6 0.0 4e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KXH42673.1 - 0.00013 22.1 1.3 0.0088 16.2 0.0 2.7 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KXH42673.1 - 0.023 14.9 0.0 0.053 13.7 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain HSP9_HSP12 PF04119.12 KXH42673.1 - 0.037 14.4 3.1 0.1 13.0 3.1 1.8 1 0 0 1 1 1 0 Heat shock protein 9/12 GST_C_6 PF17171.4 KXH42673.1 - 0.1 12.4 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain NUC153 PF08159.12 KXH42675.1 - 1.4e-13 50.4 1.5 1.4e-13 50.4 1.5 3.2 3 0 0 3 3 3 1 NUC153 domain Formyl_trans_N PF00551.19 KXH42675.1 - 0.023 14.5 0.1 6.6 6.4 0.0 3.0 2 1 1 3 3 3 0 Formyl transferase SNF2_N PF00176.23 KXH42676.1 - 9e-38 129.9 0.0 1.3e-36 126.1 0.0 2.1 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KXH42676.1 - 8.3e-16 58.3 0.0 1.7e-15 57.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 KXH42676.1 - 6.3e-09 35.4 0.0 1.3e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 KXH42676.1 - 6.8e-08 32.7 0.0 2.1e-07 31.1 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-RING_5 PF14634.6 KXH42676.1 - 3.8e-06 26.8 7.1 7.8e-06 25.8 7.1 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 KXH42676.1 - 6.5e-06 26.4 7.2 1.4e-05 25.3 7.2 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KXH42676.1 - 7.9e-06 25.6 8.7 1.6e-05 24.6 8.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KXH42676.1 - 8e-06 25.6 6.7 1.8e-05 24.5 6.7 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 KXH42676.1 - 1.7e-05 24.6 2.2 3.7e-05 23.5 2.2 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_3 PF13920.6 KXH42676.1 - 0.00013 21.8 8.7 0.00026 20.8 8.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXH42676.1 - 0.001 18.9 8.9 0.0021 17.9 8.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KXH42676.1 - 0.026 14.8 4.5 0.087 13.1 4.5 1.9 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KXH42676.1 - 0.05 13.6 7.2 0.12 12.4 7.2 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-Nse PF11789.8 KXH42676.1 - 0.3 10.9 4.6 0.68 9.8 4.6 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-ANAPC11 PF12861.7 KXH42676.1 - 0.41 10.7 4.8 1.8 8.7 4.8 2.1 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 KXH42676.1 - 0.72 10.1 8.4 1.7 8.9 8.4 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_10 PF16685.5 KXH42676.1 - 0.75 10.0 4.5 2.3 8.4 4.5 1.8 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_4 PF14570.6 KXH42676.1 - 1 9.2 6.2 2.1 8.2 6.2 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Git3 PF11710.8 KXH42678.1 - 5.4e-65 219.0 10.8 9.9e-65 218.1 10.8 1.4 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 GPR_Gpa2_C PF11970.8 KXH42678.1 - 1.7e-13 50.4 0.1 4.6e-13 49.0 0.1 1.7 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term 7tm_1 PF00001.21 KXH42678.1 - 1.1e-08 34.8 0.0 1.5e-08 34.3 0.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF4381 PF14316.6 KXH42678.1 - 1.4 9.2 7.7 5.6 7.2 2.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4381) SNF2_N PF00176.23 KXH42679.1 - 1.6e-33 115.9 1.3 2.3e-32 112.1 0.2 2.7 1 1 1 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KXH42679.1 - 3.3e-14 53.2 0.0 2.1e-12 47.4 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 KXH42679.1 - 2.2e-07 30.3 0.1 7.7e-07 28.6 0.0 1.8 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase zf-RING_UBOX PF13445.6 KXH42679.1 - 1.4e-05 25.0 2.9 3.7e-05 23.7 2.9 1.7 1 0 0 1 1 1 1 RING-type zinc-finger ResIII PF04851.15 KXH42679.1 - 7e-05 22.9 0.0 0.00021 21.3 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.25 KXH42679.1 - 0.00011 22.0 3.0 0.00023 20.9 3.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KXH42679.1 - 0.0024 18.0 3.3 0.0069 16.5 3.3 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 KXH42679.1 - 0.0052 16.6 3.4 0.0052 16.6 3.4 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KXH42679.1 - 0.0074 16.1 3.1 0.015 15.1 3.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXH42679.1 - 0.0088 16.0 2.3 0.025 14.5 2.3 1.8 1 0 0 1 1 1 1 zinc-RING finger domain Zn_Tnp_IS91 PF14319.6 KXH42679.1 - 0.012 15.6 0.7 0.53 10.4 0.6 2.8 2 0 0 2 2 2 0 Transposase zinc-binding domain zf-RING_2 PF13639.6 KXH42679.1 - 0.017 15.4 3.1 0.049 14.0 3.1 1.8 1 0 0 1 1 1 0 Ring finger domain Prok-RING_4 PF14447.6 KXH42679.1 - 0.32 10.9 4.7 0.71 9.8 4.7 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 KXH42679.1 - 1 9.5 3.7 4 7.6 3.7 2.0 1 0 0 1 1 1 0 zinc RING finger of MSL2 GATase PF00117.28 KXH42680.1 - 5.9e-12 45.8 0.0 8.3e-12 45.3 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.14 KXH42680.1 - 0.19 11.3 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain DHHA2 PF02833.14 KXH42681.1 - 3e-37 128.0 0.2 4.7e-37 127.3 0.2 1.3 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.20 KXH42681.1 - 8.9e-11 41.9 0.0 1.7e-10 41.0 0.0 1.5 1 1 0 1 1 1 1 DHH family S1-P1_nuclease PF02265.16 KXH42682.1 - 4.4e-67 226.5 0.0 5e-67 226.4 0.0 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease YjeF_N PF03853.15 KXH42682.1 - 0.049 13.5 0.0 0.085 12.7 0.0 1.4 1 0 0 1 1 1 0 YjeF-related protein N-terminus RsfS PF02410.15 KXH42683.1 - 9.9e-12 45.2 0.0 2.9e-11 43.7 0.0 1.9 2 0 0 2 2 2 1 Ribosomal silencing factor during starvation HTH_31 PF13560.6 KXH42683.1 - 0.067 13.6 0.4 16 6.0 0.0 2.8 3 0 0 3 3 3 0 Helix-turn-helix domain RNA_pol PF00940.19 KXH42684.1 - 1.7e-185 616.7 0.0 2.4e-185 616.3 0.0 1.2 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 KXH42684.1 - 2.7e-106 355.8 1.3 2.7e-106 355.8 1.3 1.8 2 0 0 2 2 2 1 DNA-directed RNA polymerase N-terminal Methyltransf_23 PF13489.6 KXH42686.1 - 1.8e-22 79.9 0.0 2.5e-22 79.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH42686.1 - 2.2e-10 41.1 0.0 1e-09 39.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH42686.1 - 3.9e-10 39.7 0.0 2.9e-05 23.9 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 KXH42686.1 - 2.9e-08 34.3 0.0 4.3e-07 30.6 0.0 2.4 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH42686.1 - 1.4e-07 32.0 0.0 2.8e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 KXH42686.1 - 0.0036 16.6 0.0 0.0093 15.3 0.0 1.9 2 1 0 2 2 2 1 O-methyltransferase domain MTS PF05175.14 KXH42686.1 - 0.008 15.7 0.0 0.014 14.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain DREV PF05219.12 KXH42686.1 - 0.039 13.0 0.0 0.057 12.5 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase Ubie_methyltran PF01209.18 KXH42686.1 - 0.061 12.6 0.0 0.77 9.0 0.0 2.1 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family PrmA PF06325.13 KXH42686.1 - 0.069 12.5 0.0 0.14 11.6 0.0 1.5 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.9 KXH42686.1 - 0.17 11.6 0.0 0.26 11.0 0.0 1.4 1 1 0 1 1 1 0 Lysine methyltransferase Ank_5 PF13857.6 KXH42687.1 - 8.5e-17 61.0 0.6 3.1e-08 33.7 0.0 4.6 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXH42687.1 - 1.3e-16 60.7 5.1 3.1e-06 27.6 0.0 5.1 5 0 0 5 5 5 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXH42687.1 - 6.8e-15 55.4 2.1 2e-06 28.3 0.1 5.0 4 2 1 5 5 5 2 Ankyrin repeats (3 copies) Ank PF00023.30 KXH42687.1 - 1.3e-12 47.5 10.4 0.00038 20.8 0.1 6.1 6 1 0 6 6 6 3 Ankyrin repeat Ank_3 PF13606.6 KXH42687.1 - 5.8e-11 41.6 6.4 0.018 15.5 0.1 6.5 7 1 0 7 7 7 3 Ankyrin repeat p450 PF00067.22 KXH42688.1 - 4.8e-51 174.0 0.0 6e-51 173.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_23 PF13489.6 KXH42689.1 - 3.1e-21 75.9 0.0 4e-21 75.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH42689.1 - 2.6e-07 31.2 0.0 9e-07 29.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH42689.1 - 7.6e-05 22.6 0.0 0.23 11.2 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 KXH42689.1 - 7.8e-05 23.4 0.0 0.00088 20.0 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH42689.1 - 8.2e-05 23.2 0.0 0.00016 22.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 KXH42689.1 - 0.0055 16.8 0.0 0.009 16.1 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase GMC_oxred_N PF00732.19 KXH42690.1 - 4.5e-64 216.6 0.0 5.8e-64 216.3 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXH42690.1 - 4e-29 102.0 0.2 7.7e-29 101.1 0.2 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Thi4 PF01946.17 KXH42690.1 - 0.00038 19.8 0.2 0.00085 18.6 0.2 1.5 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 KXH42690.1 - 0.017 15.3 0.0 0.054 13.7 0.0 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KXH42690.1 - 0.017 14.2 0.1 0.031 13.3 0.1 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein DAO PF01266.24 KXH42690.1 - 0.021 14.4 0.0 0.049 13.2 0.0 1.6 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXH42690.1 - 0.031 13.5 0.0 5.3 6.2 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXH42690.1 - 0.093 11.8 0.0 3.1 6.8 0.0 2.3 2 0 0 2 2 2 0 FAD binding domain MFS_1 PF07690.16 KXH42691.1 - 1.1e-11 44.3 52.0 7e-10 38.3 49.7 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KXH42691.1 - 1.6e-07 30.2 26.4 3.4e-07 29.1 26.3 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) AA_permease PF00324.21 KXH42692.1 - 1.3e-120 403.3 33.1 1.5e-120 403.1 33.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KXH42692.1 - 4.5e-32 111.4 36.2 5.5e-32 111.1 36.2 1.0 1 0 0 1 1 1 1 Amino acid permease GMC_oxred_N PF00732.19 KXH42694.1 - 9.4e-51 172.9 0.0 1.7e-50 172.1 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXH42694.1 - 3e-37 128.3 0.0 5.8e-37 127.4 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KXH42694.1 - 1.4e-07 31.0 1.3 0.012 14.7 0.0 2.4 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 KXH42694.1 - 0.00025 20.7 0.7 0.029 14.0 0.8 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXH42694.1 - 0.0012 18.1 0.1 0.0059 15.9 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXH42694.1 - 0.0026 17.1 1.0 1.7 7.8 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KXH42694.1 - 0.0061 15.6 0.2 0.0061 15.6 0.2 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 KXH42694.1 - 0.018 15.2 2.2 0.057 13.7 2.2 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KXH42694.1 - 0.044 12.5 1.7 0.095 11.4 0.7 1.8 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox PF00070.27 KXH42694.1 - 0.62 10.7 2.6 5.2 7.7 0.9 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KXH42694.1 - 0.84 8.7 2.9 8.5 5.3 0.6 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A ADH_zinc_N PF00107.26 KXH42696.1 - 2.1e-21 76.3 0.0 3e-21 75.8 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KXH42696.1 - 8.9e-18 64.2 0.0 1.7e-17 63.3 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 KXH42696.1 - 6.6e-07 30.4 0.0 1.4e-06 29.4 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF2855 PF11017.8 KXH42696.1 - 0.22 11.2 0.0 0.71 9.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2855) Sugar_tr PF00083.24 KXH42697.1 - 6.6e-107 358.2 16.3 7.7e-107 357.9 16.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH42697.1 - 2.8e-21 75.8 34.1 3.3e-16 59.2 12.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_tranf_2_3 PF13641.6 KXH42698.1 - 1.2e-18 67.9 0.0 1.6e-18 67.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 KXH42698.1 - 1.8e-05 24.3 0.1 0.017 14.6 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 KXH42698.1 - 7.2e-05 22.7 0.0 0.00012 21.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 TRAM1 PF08390.11 KXH42698.1 - 0.22 11.2 1.6 0.53 10.0 1.6 1.6 1 0 0 1 1 1 0 TRAM1-like protein p450 PF00067.22 KXH42700.1 - 5.8e-72 242.9 0.0 6.9e-72 242.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 AA_permease PF00324.21 KXH42701.1 - 1.3e-118 396.7 41.9 1.4e-118 396.5 41.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KXH42701.1 - 3.8e-36 124.9 48.9 6.1e-36 124.2 48.9 1.3 1 0 0 1 1 1 1 Amino acid permease Fungal_trans_2 PF11951.8 KXH42702.1 - 4e-07 29.2 1.3 0.0013 17.6 0.1 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain p450 PF00067.22 KXH42703.1 - 2.2e-78 264.1 0.0 3e-78 263.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Flavodoxin_1 PF00258.25 KXH42703.1 - 2.8e-25 89.2 0.0 6.4e-25 88.0 0.0 1.7 1 0 0 1 1 1 1 Flavodoxin FAD_binding_1 PF00667.20 KXH42703.1 - 4.8e-17 62.3 0.0 9.1e-17 61.4 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 KXH42703.1 - 4.5e-10 40.1 0.0 1.1e-09 38.9 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 KXH42703.1 - 0.00011 22.5 0.0 0.00031 21.0 0.0 1.7 2 0 0 2 2 2 1 Flavodoxin domain DnaG_DnaB_bind PF08278.11 KXH42703.1 - 0.035 14.7 0.1 0.17 12.5 0.1 2.2 1 0 0 1 1 1 0 DNA primase DnaG DnaB-binding CusF_Ec PF11604.8 KXH42703.1 - 0.082 12.9 0.0 30 4.7 0.0 3.1 3 0 0 3 3 3 0 Copper binding periplasmic protein CusF DcpS PF05652.12 KXH42704.1 - 7e-38 129.7 0.0 1.1e-37 129.0 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal DcpS_C PF11969.8 KXH42704.1 - 6e-32 110.5 0.1 9.5e-32 109.9 0.1 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding GILT PF03227.16 KXH42705.1 - 1.9e-18 66.6 0.0 3.2e-18 65.9 0.0 1.4 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) PSI_8 PF00796.18 KXH42705.1 - 0.64 9.9 3.1 1.3 8.9 3.1 1.5 1 0 0 1 1 1 0 Photosystem I reaction centre subunit VIII Hexokinase_2 PF03727.16 KXH42706.1 - 2.5e-41 141.7 0.0 3.5e-41 141.2 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 KXH42706.1 - 4.4e-39 134.4 0.0 6.2e-39 134.0 0.0 1.2 1 0 0 1 1 1 1 Hexokinase ArgJ PF01960.18 KXH42707.1 - 0.16 10.7 0.0 0.2 10.3 0.0 1.2 1 0 0 1 1 1 0 ArgJ family SLD3 PF08639.10 KXH42711.1 - 2.8e-175 584.1 1.0 2.8e-175 584.1 1.0 1.9 2 0 0 2 2 2 1 DNA replication regulator SLD3 GH131_N PF18271.1 KXH42711.1 - 0.19 11.3 0.0 0.34 10.5 0.0 1.3 1 0 0 1 1 1 0 Glycoside hydrolase 131 catalytic N-terminal domain Trs65 PF12735.7 KXH42712.1 - 1.8e-125 418.6 0.0 2.4e-125 418.1 0.0 1.2 1 0 0 1 1 1 1 TRAPP trafficking subunit Trs65 FF PF01846.19 KXH42713.1 - 1.4e-43 146.9 24.7 4.2e-14 52.5 0.3 7.0 7 1 0 7 7 7 5 FF domain WW PF00397.26 KXH42713.1 - 1.9e-18 66.2 18.0 5.4e-11 42.4 4.1 2.7 2 0 0 2 2 2 2 WW domain Lipin_mid PF16876.5 KXH42713.1 - 0.069 13.3 1.2 5.7 7.1 0.8 3.1 1 1 1 2 2 2 0 Lipin/Ned1/Smp2 multi-domain protein middle domain HycH PF07450.11 KXH42713.1 - 0.11 12.8 0.0 0.28 11.6 0.0 1.7 1 0 0 1 1 1 0 Formate hydrogenlyase maturation protein HycH Glyco_hyd_101C PF17451.2 KXH42713.1 - 0.58 10.5 7.9 14 6.0 0.2 3.0 1 1 1 2 2 2 0 Glycosyl hydrolase 101 beta sandwich domain RhoGAP-FF1 PF16512.5 KXH42713.1 - 0.6 10.8 11.9 0.87 10.3 0.2 4.4 3 1 1 4 4 4 0 p190-A and -B Rho GAPs FF domain ABC_tran PF00005.27 KXH42714.1 - 2.8e-33 115.4 0.0 8.4e-16 58.7 0.0 2.5 2 0 0 2 2 2 2 ABC transporter RLI PF04068.15 KXH42714.1 - 5.6e-13 48.5 5.9 5.6e-13 48.5 5.9 1.9 2 0 0 2 2 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI SMC_N PF02463.19 KXH42714.1 - 2.6e-11 43.4 0.6 0.00047 19.6 0.0 3.5 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KXH42714.1 - 2e-10 41.0 5.7 0.26 11.1 1.8 4.6 3 2 2 5 5 4 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KXH42714.1 - 3.7e-06 27.4 0.0 0.032 14.6 0.0 2.5 2 1 0 2 2 2 2 AAA ATPase domain AAA PF00004.29 KXH42714.1 - 1.4e-05 25.5 0.0 0.016 15.7 0.1 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KXH42714.1 - 1.6e-05 25.2 0.0 0.0035 17.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 KXH42714.1 - 2.6e-05 24.1 0.1 0.18 11.5 0.0 3.0 2 1 0 3 3 3 2 AAA ATPase domain AAA_23 PF13476.6 KXH42714.1 - 7e-05 23.4 0.0 0.018 15.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain Fer4 PF00037.27 KXH42714.1 - 0.00011 21.8 1.3 0.00011 21.8 1.3 2.9 3 0 0 3 3 3 1 4Fe-4S binding domain RsgA_GTPase PF03193.16 KXH42714.1 - 0.00013 21.9 0.0 0.31 10.9 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase Fer4_10 PF13237.6 KXH42714.1 - 0.00013 22.0 8.3 0.01 15.9 0.1 2.4 2 0 0 2 2 2 2 4Fe-4S dicluster domain AAA_29 PF13555.6 KXH42714.1 - 0.00028 20.6 0.3 0.49 10.2 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_18 PF13238.6 KXH42714.1 - 0.0003 21.3 0.1 1.4 9.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain Rad17 PF03215.15 KXH42714.1 - 0.00037 20.5 0.1 0.057 13.3 0.0 2.5 2 1 0 2 2 2 1 Rad17 P-loop domain RNA_helicase PF00910.22 KXH42714.1 - 0.00067 20.0 0.1 0.36 11.2 0.0 2.8 2 0 0 2 2 2 1 RNA helicase Fer4_6 PF12837.7 KXH42714.1 - 0.0016 18.4 11.7 0.019 15.0 1.1 2.5 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_21 PF14697.6 KXH42714.1 - 0.0018 18.3 10.8 0.0037 17.4 10.8 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain NACHT PF05729.12 KXH42714.1 - 0.0022 17.9 1.0 0.26 11.2 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_24 PF13479.6 KXH42714.1 - 0.0025 17.6 1.8 0.22 11.2 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KXH42714.1 - 0.0028 17.8 0.0 0.49 10.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain Thymidylate_kin PF02223.17 KXH42714.1 - 0.0033 17.1 0.1 2.3 7.9 0.0 3.1 3 0 0 3 3 3 1 Thymidylate kinase SRP54 PF00448.22 KXH42714.1 - 0.0034 17.0 3.0 0.097 12.3 0.1 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_13 PF13166.6 KXH42714.1 - 0.0039 15.9 0.0 0.0039 15.9 0.0 1.9 3 0 0 3 3 2 1 AAA domain TsaE PF02367.17 KXH42714.1 - 0.0053 16.8 0.1 0.056 13.5 0.0 2.2 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Fer4_7 PF12838.7 KXH42714.1 - 0.0058 17.2 7.4 0.015 15.8 0.3 2.5 2 0 0 2 2 2 1 4Fe-4S dicluster domain AAA_5 PF07728.14 KXH42714.1 - 0.0062 16.5 0.2 0.3 11.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 KXH42714.1 - 0.0084 16.4 0.2 1.5 9.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KXH42714.1 - 0.012 15.1 0.2 0.22 11.0 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region NB-ARC PF00931.22 KXH42714.1 - 0.019 14.1 0.0 1.5 8.0 0.0 2.4 3 0 0 3 3 2 0 NB-ARC domain Fer4_9 PF13187.6 KXH42714.1 - 0.024 14.8 9.9 0.058 13.6 10.0 1.7 1 1 0 1 1 1 0 4Fe-4S dicluster domain AAA_30 PF13604.6 KXH42714.1 - 0.061 13.0 0.2 3.8 7.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain Fer4_16 PF13484.6 KXH42714.1 - 0.075 14.0 0.3 0.075 14.0 0.3 2.7 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain VirE PF05272.11 KXH42714.1 - 0.14 11.9 0.0 8.2 6.1 0.0 2.4 2 0 0 2 2 2 0 Virulence-associated protein E ATPase PF06745.13 KXH42714.1 - 0.14 11.5 0.1 0.44 9.9 0.0 1.8 2 0 0 2 2 2 0 KaiC MMR_HSR1 PF01926.23 KXH42714.1 - 0.14 12.2 1.1 18 5.5 0.0 2.7 2 1 0 2 2 2 0 50S ribosome-binding GTPase NTPase_1 PF03266.15 KXH42714.1 - 0.25 11.2 1.6 6.6 6.6 0.1 2.6 2 0 0 2 2 2 0 NTPase PduV-EutP PF10662.9 KXH42714.1 - 0.26 11.0 2.5 0.62 9.8 0.0 2.6 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_14 PF13173.6 KXH42714.1 - 0.29 11.2 0.9 24 5.0 0.0 3.2 3 1 0 3 3 2 0 AAA domain Fer4_2 PF12797.7 KXH42714.1 - 1.4 9.2 10.5 0.48 10.6 1.1 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_8 PF13183.6 KXH42714.1 - 3.6 8.1 10.8 0.62 10.6 1.6 2.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain SNF2_N PF00176.23 KXH42715.1 - 1.3e-54 185.3 0.1 2e-54 184.6 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.24 KXH42715.1 - 8.3e-25 86.5 5.8 1.2e-15 57.1 0.8 3.0 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.31 KXH42715.1 - 6.8e-20 71.5 0.0 1.8e-19 70.1 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4208 PF13907.6 KXH42715.1 - 2.9e-17 62.9 0.0 9e-17 61.3 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4208) HDA2-3 PF11496.8 KXH42715.1 - 4.6e-08 32.6 0.0 1.3e-07 31.1 0.0 1.7 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.15 KXH42715.1 - 2.8e-07 30.7 0.0 1.9e-06 28.0 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Cdh1_DBD_1 PF18196.1 KXH42715.1 - 4.3e-05 23.8 0.3 4.3e-05 23.8 0.3 4.9 3 1 1 4 4 4 2 Chromodomain helicase DNA-binding domain 1 CDH1_2_SANT_HL1 PF18375.1 KXH42715.1 - 0.0012 19.5 1.1 0.0012 19.5 1.1 2.7 3 0 0 3 3 1 1 CDH1/2 SANT-Helical linker 1 AAA_22 PF13401.6 KXH42715.1 - 0.0017 18.6 0.0 0.0061 16.8 0.0 2.0 1 0 0 1 1 1 1 AAA domain SLIDE PF09111.10 KXH42715.1 - 0.0025 17.8 1.1 0.028 14.4 0.0 3.0 2 1 0 2 2 2 1 SLIDE SWI2_SNF2 PF18766.1 KXH42715.1 - 0.054 13.2 0.4 0.21 11.2 0.0 2.2 2 0 0 2 2 2 0 SWI2/SNF2 ATPase CHDCT2 PF08074.11 KXH42715.1 - 0.51 10.5 0.0 0.51 10.5 0.0 3.2 4 0 0 4 4 4 0 CHDCT2 (NUC038) domain SIR2 PF02146.17 KXH42716.1 - 1e-24 87.5 0.0 2.4e-24 86.2 0.0 1.6 1 1 0 1 1 1 1 Sir2 family Med16 PF11635.8 KXH42717.1 - 3.9e-80 269.8 0.0 5.7e-80 269.3 0.0 1.1 1 0 0 1 1 1 1 Mediator complex subunit 16 Ammonium_transp PF00909.21 KXH42719.1 - 3e-117 391.7 26.8 3.4e-117 391.5 26.8 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Phage_holin_2_1 PF04971.12 KXH42719.1 - 4.5 7.3 7.8 1 9.4 0.9 3.2 3 0 0 3 3 3 0 Bacteriophage P21 holin S DNA_pol_B_palm PF14792.6 KXH42720.1 - 9.4e-34 116.0 0.0 2.2e-33 114.9 0.0 1.7 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.6 KXH42720.1 - 8.5e-25 86.7 0.1 6.3e-24 83.9 0.1 2.3 2 0 0 2 2 2 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.9 KXH42720.1 - 2.4e-20 72.1 0.2 8.5e-20 70.3 0.2 2.0 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.6 KXH42720.1 - 6.8e-18 64.8 0.2 6.2e-17 61.7 0.1 2.6 3 0 0 3 3 3 1 Helix-hairpin-helix domain HHH_5 PF14520.6 KXH42720.1 - 0.011 16.3 0.6 2.7 8.7 0.0 2.9 3 0 0 3 3 3 0 Helix-hairpin-helix domain BRCT_2 PF16589.5 KXH42720.1 - 0.011 16.1 0.0 0.027 14.9 0.0 1.7 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain NTP_transf_2 PF01909.23 KXH42720.1 - 0.012 15.9 0.0 0.032 14.5 0.0 1.7 1 0 0 1 1 1 0 Nucleotidyltransferase domain Cdd1 PF11731.8 KXH42720.1 - 0.033 14.4 0.0 2.1 8.7 0.0 2.9 1 1 2 3 3 3 0 Pathogenicity locus HTH_3 PF01381.22 KXH42720.1 - 0.075 13.1 0.0 0.2 11.7 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix BRCT PF00533.26 KXH42720.1 - 0.084 13.3 0.0 0.3 11.5 0.0 2.0 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain Methyltransf_25 PF13649.6 KXH42721.1 - 2.5e-11 44.1 0.0 8e-11 42.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 KXH42721.1 - 5.6e-10 39.1 0.0 8.8e-10 38.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 KXH42721.1 - 9.2e-10 38.5 0.0 2.3e-09 37.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH42721.1 - 2.8e-08 34.3 0.0 1.2e-07 32.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXH42721.1 - 1.5e-05 24.9 0.0 4.6e-05 23.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_9 PF08003.11 KXH42721.1 - 2.5e-05 23.3 0.1 3.7e-05 22.8 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_12 PF08242.12 KXH42721.1 - 0.00031 21.4 0.0 0.00074 20.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 KXH42721.1 - 0.00032 20.7 0.1 0.00055 19.9 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXH42721.1 - 0.0046 16.5 0.0 0.007 15.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 KXH42721.1 - 0.0047 16.3 0.0 0.0067 15.7 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PRMT5 PF05185.16 KXH42721.1 - 0.0091 15.9 0.1 0.019 14.8 0.1 1.6 1 1 0 1 1 1 1 PRMT5 arginine-N-methyltransferase IPI_T4 PF11634.8 KXH42721.1 - 0.019 14.9 0.1 10 6.2 0.0 2.6 2 0 0 2 2 2 0 Nuclease inhibitor from bacteriophage T4 Methyltransf_32 PF13679.6 KXH42721.1 - 0.033 14.2 0.0 0.058 13.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Zn_clus PF00172.18 KXH42722.1 - 4.9e-07 29.8 9.8 8.1e-07 29.1 9.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Arc PF03869.14 KXH42723.1 - 0.51 10.2 6.5 2.3 8.1 0.2 2.9 2 0 0 2 2 2 0 Arc-like DNA binding domain TetR_C_11 PF16859.5 KXH42723.1 - 0.7 10.2 11.3 0.08 13.3 4.7 2.8 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain Filament PF00038.21 KXH42723.1 - 0.75 9.3 78.8 0.02 14.5 10.2 5.8 4 2 1 6 6 6 0 Intermediate filament protein Lip_prot_lig_C PF10437.9 KXH42723.1 - 8.5 6.5 6.2 2.6 8.1 0.2 3.3 4 1 0 4 4 4 0 Bacterial lipoate protein ligase C-terminus PGM_PMM_I PF02878.16 KXH42724.1 - 4e-18 65.5 0.1 8e-08 32.1 0.0 2.8 1 1 1 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 KXH42724.1 - 8e-11 42.0 0.7 3.8e-10 39.8 0.3 2.3 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.16 KXH42724.1 - 0.00072 19.7 0.0 0.0019 18.3 0.0 1.8 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 KXH42724.1 - 0.0027 18.3 0.7 0.062 13.9 0.7 2.9 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II ERCC4 PF02732.15 KXH42725.1 - 2.3e-23 83.1 0.0 3.8e-23 82.4 0.0 1.4 1 0 0 1 1 1 1 ERCC4 domain HHH_8 PF14716.6 KXH42725.1 - 0.0039 17.5 0.0 0.01 16.2 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain HTH_27 PF13463.6 KXH42725.1 - 0.016 15.7 0.0 0.085 13.4 0.0 2.3 2 0 0 2 2 2 0 Winged helix DNA-binding domain HTH_45 PF14947.6 KXH42725.1 - 0.081 12.9 0.1 0.35 10.9 0.0 2.1 2 0 0 2 2 2 0 Winged helix-turn-helix Lum_binding PF00677.17 KXH42726.1 - 6e-40 135.1 0.2 3.4e-21 75.0 0.0 2.3 2 1 0 2 2 2 2 Lumazine binding domain Peptidase_S10 PF00450.22 KXH42727.1 - 3.7e-75 253.9 0.7 4.9e-75 253.5 0.7 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Sugar_tr PF00083.24 KXH42728.1 - 4.3e-24 85.2 28.0 1.5e-15 57.0 10.3 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter Pkinase PF00069.25 KXH42729.1 - 1.4e-60 204.9 0.0 5.2e-38 130.9 0.1 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXH42729.1 - 6.5e-28 97.7 0.0 2.9e-20 72.7 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.24 KXH42729.1 - 1e-15 57.8 0.0 2.1e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.6 KXH42729.1 - 6.5e-06 25.7 0.1 0.0029 17.0 0.0 2.9 3 0 0 3 3 3 2 Kinase-like APH PF01636.23 KXH42729.1 - 7.6e-05 22.8 0.0 0.0029 17.6 0.1 3.0 2 1 1 3 3 3 1 Phosphotransferase enzyme family PAS_9 PF13426.7 KXH42729.1 - 0.011 16.0 0.0 0.035 14.4 0.0 1.9 1 0 0 1 1 1 0 PAS domain Haspin_kinase PF12330.8 KXH42729.1 - 0.011 14.7 0.1 0.019 13.9 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 KXH42729.1 - 0.072 12.4 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 KXH42729.1 - 0.074 12.1 0.1 0.13 11.3 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 PAS PF00989.25 KXH42729.1 - 0.085 12.9 0.0 0.34 10.9 0.0 2.0 1 1 1 2 2 2 0 PAS fold Acyltransferase PF01553.21 KXH42731.1 - 4.5e-15 55.5 0.0 6.3e-15 55.0 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 KXH42731.1 - 1.2e-10 41.3 0.1 3.7e-10 39.8 0.1 1.7 1 0 0 1 1 1 1 Acyltransferase C-terminus LAL_C2 PF18603.1 KXH42731.1 - 0.0036 17.4 0.0 0.0056 16.8 0.0 1.3 1 0 0 1 1 1 1 L-amino acid ligase C-terminal domain 2 zf-CHY PF05495.12 KXH42746.1 - 2.3e-10 40.8 10.3 2.3e-10 40.8 10.3 3.4 2 1 0 2 2 2 1 CHY zinc finger RWD PF05773.22 KXH42746.1 - 9.6e-05 22.6 0.3 0.0056 16.9 0.0 2.4 2 0 0 2 2 2 1 RWD domain zinc_ribbon_15 PF17032.5 KXH42746.1 - 0.2 12.4 0.3 0.2 12.4 0.3 3.2 3 1 0 3 3 3 0 zinc-ribbon family DUF3243 PF11588.8 KXH42747.1 - 0.15 12.4 0.0 0.35 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3243) Fungal_trans PF04082.18 KXH42748.1 - 1.4e-21 76.7 0.0 2.1e-21 76.2 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH42748.1 - 0.0037 17.3 8.5 0.0071 16.5 8.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.13 KXH42748.1 - 0.11 12.7 0.5 0.24 11.6 0.5 1.5 1 0 0 1 1 1 0 Gal4-like dimerisation domain Sugar_tr PF00083.24 KXH42749.1 - 3.7e-87 293.1 23.5 4.3e-87 292.8 23.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH42749.1 - 1.8e-28 99.5 32.1 1.7e-26 93.0 21.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PRK PF00485.18 KXH42750.1 - 8e-08 32.2 0.0 1.2e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 KXH42750.1 - 0.00012 22.6 0.0 0.00039 21.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KXH42750.1 - 0.00039 20.9 0.0 0.00081 19.8 0.0 1.6 2 0 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.22 KXH42750.1 - 0.00043 19.6 0.0 0.00095 18.4 0.0 1.5 2 0 0 2 2 2 1 NB-ARC domain NACHT PF05729.12 KXH42750.1 - 0.00051 20.0 0.0 0.0036 17.3 0.0 2.3 3 0 0 3 3 3 1 NACHT domain Zeta_toxin PF06414.12 KXH42750.1 - 0.0007 18.9 0.1 0.0027 17.0 0.0 2.0 2 0 0 2 2 2 1 Zeta toxin NTPase_1 PF03266.15 KXH42750.1 - 0.00084 19.3 0.0 0.0029 17.5 0.0 1.8 2 0 0 2 2 2 1 NTPase AAA PF00004.29 KXH42750.1 - 0.001 19.5 0.0 0.0018 18.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KXH42750.1 - 0.0012 19.1 0.0 0.0022 18.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KXH42750.1 - 0.0012 19.1 0.1 0.0021 18.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KXH42750.1 - 0.0022 18.2 0.1 0.0099 16.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KXH42750.1 - 0.0026 17.8 0.0 0.0067 16.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 KXH42750.1 - 0.0038 17.0 0.0 0.0067 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 KXH42750.1 - 0.004 16.3 0.0 0.0053 15.8 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_17 PF13207.6 KXH42750.1 - 0.0078 16.6 0.3 0.026 14.9 0.1 2.0 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 KXH42750.1 - 0.0091 16.0 0.0 0.032 14.2 0.0 1.8 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 KXH42750.1 - 0.022 14.5 0.0 0.073 12.8 0.0 1.8 1 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 KXH42750.1 - 0.023 14.3 0.1 0.059 12.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KXH42750.1 - 0.026 15.1 0.0 0.12 12.8 0.0 2.0 1 1 0 1 1 1 0 ABC transporter SRP54 PF00448.22 KXH42750.1 - 0.029 14.0 0.0 0.044 13.4 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Mg_chelatase PF01078.21 KXH42750.1 - 0.031 13.7 0.0 0.047 13.1 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 KXH42750.1 - 0.032 14.6 0.0 0.057 13.8 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_11 PF13086.6 KXH42750.1 - 0.071 12.9 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KXH42750.1 - 0.075 12.5 0.0 0.16 11.5 0.0 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region RuvB_N PF05496.12 KXH42750.1 - 0.075 12.8 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_29 PF13555.6 KXH42750.1 - 0.12 12.2 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain cobW PF02492.19 KXH42750.1 - 0.12 11.9 0.0 0.25 10.9 0.0 1.5 2 0 0 2 2 1 0 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.17 KXH42750.1 - 0.15 11.8 0.0 0.34 10.7 0.0 1.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein KAP_NTPase PF07693.14 KXH42750.1 - 0.16 11.2 0.0 0.18 11.0 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain KTI12 PF08433.10 KXH42750.1 - 0.17 11.3 0.0 0.26 10.7 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 CPT PF07931.12 KXH42750.1 - 0.34 10.8 2.6 5.2 6.9 0.0 2.4 1 1 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein ADH_N PF08240.12 KXH42751.1 - 1.8e-31 108.3 0.2 1.8e-31 108.3 0.2 2.2 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXH42751.1 - 8.7e-25 87.2 0.5 1.9e-24 86.1 0.5 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KXH42751.1 - 7.8e-09 35.3 0.7 5.8e-08 32.5 0.7 2.1 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KXH42751.1 - 1.4e-05 26.2 0.0 4.1e-05 24.6 0.0 1.9 1 1 0 1 1 1 1 Zinc-binding dehydrogenase CMAS PF02353.20 KXH42751.1 - 0.00018 20.9 0.0 0.00029 20.2 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 KXH42751.1 - 0.0002 22.0 0.0 0.00046 20.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain 2-Hacid_dh_C PF02826.19 KXH42751.1 - 0.013 14.8 0.0 0.023 14.1 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_11 PF08241.12 KXH42751.1 - 0.015 16.0 0.0 0.031 14.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 KXH42751.1 - 0.016 15.0 0.1 0.037 13.8 0.1 1.6 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 KXH42751.1 - 0.036 13.5 0.2 0.058 12.8 0.2 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Hexapep PF00132.24 KXH42751.1 - 0.092 12.5 0.7 0.24 11.2 0.7 1.7 1 0 0 1 1 1 0 Bacterial transferase hexapeptide (six repeats) DUF1731 PF08338.11 KXH42751.1 - 0.15 11.9 0.0 7.8 6.4 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) adh_short_C2 PF13561.6 KXH42752.1 - 6.9e-58 196.0 1.8 8.2e-58 195.7 1.8 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXH42752.1 - 3.2e-44 150.7 1.8 4e-44 150.4 1.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXH42752.1 - 3.1e-14 53.3 1.5 5.3e-14 52.5 1.5 1.3 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KXH42752.1 - 0.0076 15.4 0.2 0.017 14.2 0.1 1.5 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KXH42752.1 - 0.013 15.0 1.0 0.033 13.6 1.0 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Dehydratase_MU PF02288.15 KXH42752.1 - 0.074 12.9 0.3 0.14 12.0 0.3 1.4 1 0 0 1 1 1 0 Dehydratase medium subunit NAD_binding_2 PF03446.15 KXH42752.1 - 0.078 13.1 1.4 0.12 12.6 0.4 1.8 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase RmlD_sub_bind PF04321.17 KXH42752.1 - 0.099 11.7 4.1 3.3 6.7 1.1 2.2 1 1 0 2 2 2 0 RmlD substrate binding domain SET PF00856.28 KXH42753.1 - 4.3e-11 43.5 0.0 3.6e-10 40.5 0.0 2.1 1 1 0 1 1 1 1 SET domain Sugar_tr PF00083.24 KXH42755.1 - 3.3e-82 276.7 20.9 4.1e-82 276.4 20.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH42755.1 - 2.5e-17 62.8 42.2 7.4e-17 61.3 20.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily YebO PF13974.6 KXH42755.1 - 0.16 12.0 0.0 0.36 11.0 0.0 1.6 1 0 0 1 1 1 0 YebO-like protein DUF2456 PF10445.9 KXH42755.1 - 1.5 8.9 7.0 14 5.9 0.7 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2456) SNF2_N PF00176.23 KXH42757.1 - 3.7e-24 85.1 0.0 6.6e-24 84.3 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KXH42757.1 - 4e-11 43.2 0.0 9e-11 42.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXH42757.1 - 9.6e-06 25.7 0.0 2.9e-05 24.1 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit BTV_NS2 PF04514.12 KXH42759.1 - 0.021 13.7 3.1 0.036 12.9 3.1 1.4 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Efg1 PF10153.9 KXH42759.1 - 1.5 9.2 6.5 7 7.1 0.4 2.5 2 0 0 2 2 2 0 rRNA-processing protein Efg1 PBP PF01161.20 KXH42762.1 - 1.9e-14 54.1 0.0 2.6e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein FANCI_S2 PF14676.6 KXH42762.1 - 0.09 13.1 0.0 0.13 12.6 0.0 1.2 1 0 0 1 1 1 0 FANCI solenoid 2 NUDIX_4 PF14815.6 KXH42763.1 - 1.3e-20 73.5 0.0 3.9e-20 71.9 0.0 1.9 1 0 0 1 1 1 1 NUDIX domain HhH-GPD PF00730.25 KXH42763.1 - 1.2e-19 70.7 0.0 3.1e-19 69.4 0.0 1.7 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 KXH42763.1 - 5.9e-06 25.9 0.1 2e-05 24.2 0.1 2.0 1 0 0 1 1 1 1 Helix-hairpin-helix motif FeS PF04060.13 KXH42763.1 - 0.051 13.2 1.1 0.13 11.9 1.1 1.7 1 0 0 1 1 1 0 Putative Fe-S cluster EndIII_4Fe-2S PF10576.9 KXH42763.1 - 0.1 13.0 0.8 0.43 11.0 0.8 2.1 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III Whib PF02467.16 KXH42763.1 - 3.2 8.4 6.0 1.2 9.8 0.7 2.7 2 0 0 2 2 2 0 Transcription factor WhiB Pyr_redox_2 PF07992.14 KXH42764.1 - 1.3e-11 44.3 0.0 6.6e-09 35.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KXH42764.1 - 1.6e-10 40.0 0.1 4.1e-09 35.4 0.0 2.1 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KXH42764.1 - 1.9e-09 37.2 0.0 1.3e-08 34.5 0.0 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXH42764.1 - 7.8e-09 35.1 0.1 1.6e-06 27.5 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KXH42764.1 - 1.5e-07 31.6 0.0 5.2e-07 29.8 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KXH42764.1 - 0.00018 20.9 0.1 0.00089 18.6 0.0 2.0 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.12 KXH42764.1 - 0.00035 19.8 0.0 0.00091 18.4 0.0 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 KXH42764.1 - 0.00062 19.8 1.9 0.032 14.2 0.0 3.3 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 KXH42764.1 - 0.0019 18.7 0.1 1 10.0 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 KXH42764.1 - 0.034 13.5 0.1 0.082 12.3 0.1 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 KXH42764.1 - 0.042 12.9 0.0 0.068 12.2 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.24 KXH42764.1 - 0.074 12.6 3.4 0.1 12.1 0.0 2.8 2 2 0 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.22 KXH42764.1 - 0.13 11.4 0.1 2.7 7.0 0.1 2.4 2 0 0 2 2 2 0 Glucose inhibited division protein A Pectate_lyase PF03211.13 KXH42765.1 - 4.9e-85 284.2 9.5 5.8e-85 283.9 9.5 1.0 1 0 0 1 1 1 1 Pectate lyase Hydantoinase_B PF02538.14 KXH42766.1 - 1.3e-212 706.8 0.1 2.5e-212 705.9 0.1 1.4 2 0 0 2 2 2 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 KXH42766.1 - 1.1e-101 340.0 0.0 3.9e-100 334.9 0.0 2.3 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 KXH42766.1 - 1.7e-59 200.5 0.7 8.3e-57 191.7 0.0 3.3 3 0 0 3 3 3 2 Hydantoinase/oxoprolinase N-terminal region MFS_1 PF07690.16 KXH42767.1 - 1.2e-36 126.4 19.0 1.2e-36 126.4 19.0 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily PNK3P PF08645.11 KXH42768.1 - 1.5e-58 197.1 0.0 2.2e-58 196.5 0.0 1.3 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.6 KXH42768.1 - 1.3e-27 96.7 0.0 6.2e-25 88.0 0.0 2.4 1 1 0 1 1 1 1 AAA domain Rad17 PF03215.15 KXH42768.1 - 0.01 15.8 0.0 0.02 14.8 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain Zeta_toxin PF06414.12 KXH42768.1 - 0.15 11.3 0.0 3.7 6.8 0.0 2.8 2 1 1 3 3 3 0 Zeta toxin Med18 PF09637.10 KXH42769.1 - 3.2e-24 86.1 0.0 8.4e-12 45.4 0.0 2.0 2 0 0 2 2 2 2 Med18 protein FRP PF18032.1 KXH42769.1 - 0.46 11.1 3.0 5 7.8 0.1 2.6 3 0 0 3 3 3 0 Photoprotection regulator fluorescence recovery protein Glyco_hydro_61 PF03443.14 KXH42770.1 - 9e-65 218.4 0.6 1.4e-64 217.8 0.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Glyco_hydro_16 PF00722.21 KXH42771.1 - 2e-07 30.6 0.3 2.9e-05 23.6 0.1 2.1 2 0 0 2 2 2 2 Glycosyl hydrolases family 16 SKN1 PF03935.15 KXH42771.1 - 1.7e-05 23.5 0.1 0.0096 14.4 0.1 2.2 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) DUF3433 PF11915.8 KXH42772.1 - 0.00032 21.1 1.9 0.00098 19.5 1.9 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3433) Hum_adeno_E3A PF05393.11 KXH42772.1 - 0.0068 16.4 0.8 0.14 12.1 0.3 2.4 2 0 0 2 2 2 1 Human adenovirus early E3A glycoprotein NACHT PF05729.12 KXH42773.1 - 2.5e-10 40.5 0.1 7.6e-05 22.7 0.0 3.0 2 0 0 2 2 2 2 NACHT domain AAA_16 PF13191.6 KXH42773.1 - 1.7e-05 25.3 0.1 0.0018 18.6 0.0 3.7 3 1 0 3 3 3 1 AAA ATPase domain ABC_tran PF00005.27 KXH42773.1 - 4.5e-05 24.0 0.1 0.012 16.1 0.0 2.7 2 0 0 2 2 2 1 ABC transporter Ank_4 PF13637.6 KXH42773.1 - 0.00019 21.9 0.0 0.41 11.3 0.0 4.3 5 0 0 5 5 5 1 Ankyrin repeats (many copies) AAA_22 PF13401.6 KXH42773.1 - 0.00036 20.8 0.0 0.0022 18.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KXH42773.1 - 0.004 16.9 0.1 0.022 14.5 0.1 2.2 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_23 PF13476.6 KXH42773.1 - 0.0046 17.5 0.0 0.025 15.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KXH42773.1 - 0.0075 16.0 0.0 0.02 14.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF87 PF01935.17 KXH42773.1 - 0.042 13.9 1.1 0.93 9.5 0.1 2.7 2 0 0 2 2 2 0 Helicase HerA, central domain RsgA_GTPase PF03193.16 KXH42773.1 - 0.047 13.6 0.0 0.17 11.7 0.0 1.8 2 0 0 2 2 2 0 RsgA GTPase AAA_18 PF13238.6 KXH42773.1 - 0.074 13.6 0.0 0.72 10.4 0.0 2.7 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 KXH42773.1 - 0.085 13.3 0.0 0.21 12.0 0.0 1.7 1 0 0 1 1 1 0 RNA helicase NUDIX PF00293.28 KXH42778.1 - 5.9e-13 49.0 0.0 1.3e-12 47.9 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain AAA_16 PF13191.6 KXH42778.1 - 6.9e-08 33.0 0.3 3.5e-07 30.8 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 KXH42778.1 - 5e-07 29.8 0.0 1.2e-06 28.5 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 KXH42778.1 - 0.0017 18.6 0.1 0.016 15.5 0.0 2.7 3 1 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 KXH42778.1 - 0.0034 17.7 0.0 0.0092 16.4 0.0 1.7 1 0 0 1 1 1 1 RNA helicase MMR_HSR1 PF01926.23 KXH42778.1 - 0.02 15.0 0.0 0.069 13.2 0.0 1.9 1 0 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.27 KXH42778.1 - 0.02 15.4 1.5 0.042 14.4 0.0 2.3 3 0 0 3 3 2 0 ABC transporter AAA_25 PF13481.6 KXH42778.1 - 0.023 14.3 0.0 0.11 12.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KXH42778.1 - 0.029 14.1 0.0 0.061 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF4916 PF16262.5 KXH42778.1 - 0.033 13.7 0.0 0.065 12.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4916) DUF87 PF01935.17 KXH42778.1 - 0.036 14.2 0.8 0.81 9.7 0.0 2.9 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_18 PF13238.6 KXH42778.1 - 0.042 14.4 0.1 0.24 12.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain Ploopntkinase3 PF18751.1 KXH42778.1 - 0.11 12.4 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 DUF4615 PF15393.6 KXH42778.1 - 0.13 12.8 0.9 0.35 11.4 0.9 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4615) AAA PF00004.29 KXH42778.1 - 0.14 12.6 0.0 0.56 10.6 0.0 2.1 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 KXH42778.1 - 0.15 11.8 0.2 0.41 10.4 0.2 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain FliX PF10768.9 KXH42778.1 - 0.94 10.0 4.4 16 6.0 0.7 2.8 3 0 0 3 3 2 0 Class II flagellar assembly regulator Zn_clus PF00172.18 KXH42779.1 - 1.5e-05 25.0 7.7 4.7e-05 23.4 7.7 1.9 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KXH42779.1 - 1.5e-05 24.0 1.0 0.0024 16.7 0.2 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Chloroa_b-bind PF00504.21 KXH42779.1 - 0.035 14.6 0.0 0.062 13.8 0.0 1.4 1 0 0 1 1 1 0 Chlorophyll A-B binding protein Acetyltransf_1 PF00583.25 KXH42780.1 - 1.1e-05 25.6 0.0 1.6e-05 25.1 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXH42780.1 - 0.00035 20.9 0.0 0.00063 20.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KXH42780.1 - 0.0011 18.9 0.0 0.0018 18.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KXH42780.1 - 0.05 13.7 0.0 0.87 9.7 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KXH42780.1 - 0.18 11.9 0.0 0.35 11.0 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase PhyH PF05721.13 KXH42781.1 - 2.4e-26 93.3 0.0 3.2e-26 92.9 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) AAL_decarboxy PF03306.13 KXH42781.1 - 0.028 13.8 0.0 0.038 13.3 0.0 1.1 1 0 0 1 1 1 0 Alpha-acetolactate decarboxylase ADH_N PF08240.12 KXH42783.1 - 7.5e-25 86.9 8.1 1.4e-24 86.0 8.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXH42783.1 - 1.1e-22 80.4 0.0 7.4e-22 77.7 0.0 2.2 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXH42783.1 - 4.2e-05 24.6 0.0 7.3e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KXH42783.1 - 0.00036 19.9 0.0 0.00072 18.9 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 KXH42783.1 - 0.0018 17.7 0.1 0.0031 16.9 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 KXH42783.1 - 0.036 13.7 0.0 0.061 13.0 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DUF2855 PF11017.8 KXH42784.1 - 5.6e-99 332.1 0.1 6.5e-99 331.9 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2855) RMMBL PF07521.12 KXH42784.1 - 0.026 14.4 0.0 0.047 13.6 0.0 1.4 1 0 0 1 1 1 0 Zn-dependent metallo-hydrolase RNA specificity domain PA_decarbox PF05870.11 KXH42785.1 - 1.5e-08 34.4 0.2 2.5e-08 33.7 0.2 1.3 1 0 0 1 1 1 1 Phenolic acid decarboxylase (PAD) HET PF06985.11 KXH42786.1 - 1e-30 107.0 0.2 2e-30 106.1 0.2 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.7 KXH42787.1 - 4.9e-34 116.8 0.0 1.5e-14 54.3 0.0 2.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 KXH42787.1 - 2.3e-15 56.3 0.1 2.1e-05 24.7 0.0 4.5 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.6 KXH42787.1 - 6e-14 52.2 0.0 3.3e-07 30.7 0.0 3.2 2 2 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXH42787.1 - 6.9e-13 47.5 0.0 0.00019 21.6 0.0 4.6 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 KXH42787.1 - 8.4e-12 45.1 0.0 1.7e-08 34.6 0.0 3.3 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Glyco_hydro_17 PF00332.18 KXH42788.1 - 7.9e-09 35.5 2.0 0.0022 17.7 0.1 2.2 1 1 1 2 2 2 2 Glycosyl hydrolases family 17 Gly-zipper_YMGG PF13441.6 KXH42788.1 - 0.0011 18.6 5.6 0.0011 18.6 5.6 3.4 3 1 0 3 3 3 2 YMGG-like Gly-zipper SNARE PF05739.19 KXH42788.1 - 0.055 13.5 1.5 0.095 12.7 1.5 1.4 1 0 0 1 1 1 0 SNARE domain Cupin_7 PF12973.7 KXH42789.1 - 0.029 14.3 0.4 0.3 11.0 0.1 2.3 2 0 0 2 2 2 0 ChrR Cupin-like domain Peroxidase_2 PF01328.17 KXH42790.1 - 3.8e-45 154.7 0.0 5.2e-45 154.3 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 bZIP_1 PF00170.21 KXH42791.1 - 5.6e-07 29.6 8.0 9.4e-07 28.8 8.0 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KXH42791.1 - 5.5e-06 26.4 8.4 1.1e-05 25.4 8.4 1.5 1 0 0 1 1 1 1 Basic region leucine zipper Takusan PF04822.13 KXH42791.1 - 0.0049 16.7 2.8 0.015 15.1 2.8 1.9 1 0 0 1 1 1 1 Takusan bZIP_Maf PF03131.17 KXH42791.1 - 0.27 11.8 10.7 0.052 14.1 6.1 1.9 2 0 0 2 2 2 0 bZIP Maf transcription factor Zn_clus PF00172.18 KXH42792.1 - 3.3e-05 23.9 4.9 6.9e-05 22.9 4.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Baculo_8kDa PF06096.11 KXH42792.1 - 0.038 14.1 0.0 0.11 12.7 0.0 1.7 1 0 0 1 1 1 0 Baculoviridae 8.2 KDa protein FAD_binding_3 PF01494.19 KXH42793.1 - 1.2e-24 87.3 0.0 2e-24 86.5 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KXH42793.1 - 1.6e-05 24.3 0.1 0.0074 15.6 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXH42793.1 - 0.0011 19.5 0.1 0.021 15.4 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXH42793.1 - 0.0045 17.2 0.1 0.0099 16.1 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KXH42793.1 - 0.0082 15.4 0.1 0.52 9.5 0.2 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KXH42793.1 - 0.018 14.3 0.1 0.38 10.0 0.0 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.12 KXH42793.1 - 0.033 13.2 0.1 0.14 11.2 0.0 2.0 2 1 0 2 2 2 0 Lycopene cyclase protein DAO PF01266.24 KXH42793.1 - 0.091 12.3 0.2 0.35 10.4 0.2 1.8 1 1 1 2 2 2 0 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KXH42793.1 - 0.13 11.5 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 KXH42793.1 - 0.15 10.8 0.0 13 4.3 0.0 2.3 2 0 0 2 2 2 0 HI0933-like protein Methyltransf_2 PF00891.18 KXH42797.1 - 2.9e-23 82.3 0.0 4.8e-23 81.6 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain MarR_2 PF12802.7 KXH42797.1 - 0.0039 17.1 0.0 0.0095 15.8 0.0 1.6 1 0 0 1 1 1 1 MarR family mTERF PF02536.14 KXH42797.1 - 0.061 12.2 0.0 0.25 10.2 0.0 1.9 2 0 0 2 2 2 0 mTERF Cyclin PF08613.11 KXH42800.1 - 1.2e-09 38.7 0.0 2e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 KXH42800.1 - 0.03 14.1 0.0 0.054 13.2 0.0 1.4 1 0 0 1 1 1 0 Cyclin, N-terminal domain MethyTransf_Reg PF10119.9 KXH42932.1 - 0.12 13.1 0.0 0.17 12.6 0.0 1.2 1 0 0 1 1 1 0 Predicted methyltransferase regulatory domain Abhydrolase_1 PF00561.20 KXH42934.1 - 4.3e-18 65.9 0.0 3e-12 46.7 0.1 2.8 2 1 1 3 3 3 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXH42934.1 - 1.9e-16 61.3 1.9 2.6e-16 60.9 1.9 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXH42934.1 - 5e-14 52.1 0.1 2.2e-13 50.1 0.1 1.8 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydro_lipase PF04083.16 KXH42934.1 - 0.16 11.5 0.0 0.32 10.6 0.0 1.5 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region Dioxygenase_C PF00775.21 KXH42935.1 - 0.00018 21.0 0.1 0.00029 20.3 0.1 1.3 1 0 0 1 1 1 1 Dioxygenase adh_short_C2 PF13561.6 KXH42936.1 - 3.1e-55 187.3 2.9 3.8e-55 187.0 2.9 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXH42936.1 - 1.6e-45 155.0 1.3 2e-45 154.7 1.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXH42936.1 - 3e-10 40.3 0.6 8.5e-10 38.8 0.6 1.6 1 1 0 1 1 1 1 KR domain Peptidase_M41 PF01434.18 KXH42937.1 - 8.4e-58 195.4 0.8 1.5e-57 194.6 0.8 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 KXH42937.1 - 6.7e-43 146.3 0.0 1.6e-42 145.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KXH42937.1 - 9.6e-09 34.9 0.1 2.1e-08 33.8 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain TIP49 PF06068.13 KXH42937.1 - 5.7e-05 22.5 0.0 0.00011 21.6 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_5 PF07728.14 KXH42937.1 - 5.8e-05 23.1 0.0 0.00019 21.4 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KXH42937.1 - 0.00061 20.2 1.7 0.0063 16.9 0.2 3.2 2 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 KXH42937.1 - 0.0011 18.7 0.0 0.0023 17.7 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KXH42937.1 - 0.0012 19.1 0.0 0.14 12.4 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KXH42937.1 - 0.002 18.3 0.0 0.0052 16.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 KXH42937.1 - 0.0085 15.5 0.2 0.019 14.4 0.2 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 KXH42937.1 - 0.012 15.4 0.0 0.042 13.6 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_2 PF07724.14 KXH42937.1 - 0.026 14.6 0.0 0.073 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_25 PF13481.6 KXH42937.1 - 0.067 12.8 0.5 2.5 7.6 0.2 2.4 1 1 1 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KXH42937.1 - 0.067 12.5 1.0 0.26 10.5 0.4 2.2 1 1 1 2 2 2 0 Zeta toxin AAA_18 PF13238.6 KXH42937.1 - 0.13 12.8 0.0 0.4 11.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.6 KXH42937.1 - 0.19 12.2 0.6 0.35 11.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain BSD PF03909.17 KXH43121.1 - 1.2e-19 70.0 0.2 3e-19 68.8 0.2 1.7 1 0 0 1 1 1 1 BSD domain Suf PF05843.14 KXH43121.1 - 0.0044 17.0 2.5 0.0044 17.0 2.5 2.2 2 0 0 2 2 2 1 Suppressor of forked protein (Suf) Sigma70_r2 PF04542.14 KXH43121.1 - 0.0086 15.8 0.5 0.026 14.3 0.0 2.0 2 0 0 2 2 2 1 Sigma-70 region 2 WGG PF10273.9 KXH43122.1 - 2.9e-27 95.2 0.1 5.3e-27 94.3 0.1 1.4 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 RRP7 PF12923.7 KXH43122.1 - 0.0051 16.9 0.8 0.012 15.7 0.1 1.9 2 0 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain CAF20 PF17052.5 KXH43122.1 - 0.065 13.4 0.6 0.099 12.8 0.5 1.6 1 1 0 1 1 1 0 Cap associated factor Abhydrolase_3 PF07859.13 KXH43123.1 - 3e-41 141.6 0.0 2.8e-31 109.0 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KXH43123.1 - 3.3e-14 52.6 0.0 6.1e-14 51.7 0.0 1.3 1 0 0 1 1 1 1 Steryl acetyl hydrolase COesterase PF00135.28 KXH43123.1 - 0.0029 16.5 0.0 0.056 12.3 0.0 2.1 2 0 0 2 2 2 1 Carboxylesterase family MRP-L27 PF09809.9 KXH43124.1 - 3.8e-18 65.4 0.4 5.7e-18 64.8 0.4 1.4 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L27 THOC7 PF05615.13 KXH43125.1 - 0.00092 19.5 4.2 0.0016 18.7 4.2 1.4 1 0 0 1 1 1 1 Tho complex subunit 7 Tektin PF03148.14 KXH43125.1 - 0.003 16.4 6.4 0.0042 15.9 6.4 1.2 1 0 0 1 1 1 1 Tektin family RasGAP_C PF03836.15 KXH43125.1 - 0.14 12.3 2.4 1.3 9.1 0.7 2.3 2 0 0 2 2 2 0 RasGAP C-terminus JIP_LZII PF16471.5 KXH43125.1 - 0.36 11.0 4.5 0.21 11.8 1.5 2.1 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II Phlebovirus_NSM PF07246.11 KXH43125.1 - 0.4 10.0 1.7 0.58 9.5 1.7 1.2 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M ZapA PF05164.13 KXH43125.1 - 0.64 10.5 4.6 0.69 10.4 3.1 1.9 1 1 1 2 2 2 0 Cell division protein ZapA DUF4200 PF13863.6 KXH43125.1 - 4.7 7.6 13.4 0.37 11.2 8.0 1.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4200) RNase_H PF00075.24 KXH43126.1 - 1.5e-07 31.7 0.3 4.6e-07 30.1 0.3 1.8 1 1 0 1 1 1 1 RNase H RVT_3 PF13456.6 KXH43126.1 - 0.0053 16.6 0.0 4.4 7.1 0.0 2.7 2 1 1 3 3 3 2 Reverse transcriptase-like Peptidase_S8 PF00082.22 KXH43127.1 - 1.1e-44 153.0 0.2 1.6e-44 152.4 0.2 1.2 1 0 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 KXH43127.1 - 8.4e-08 32.9 0.0 2.9e-07 31.2 0.0 1.9 2 0 0 2 2 2 1 Fn3-like domain Alpha-amylase PF00128.24 KXH43128.1 - 4.7e-24 85.6 4.3 1.2e-21 77.7 0.8 2.9 3 1 0 3 3 3 2 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.11 KXH43128.1 - 2.3e-16 60.3 0.5 3.8e-16 59.5 0.5 1.3 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 KXH43128.1 - 1.8e-06 27.6 0.0 3.5e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KXH43128.1 - 0.007 16.4 0.0 0.015 15.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Alpha-amylase PF00128.24 KXH43129.1 - 1e-50 173.2 0.9 1.5e-50 172.6 0.9 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.11 KXH43129.1 - 2.6e-24 85.3 0.5 5.2e-24 84.4 0.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) DPBB_1 PF03330.18 KXH43193.1 - 1.5e-08 34.8 0.6 6.1e-08 32.8 0.2 2.4 2 1 0 2 2 2 1 Lytic transglycolase Barwin PF00967.17 KXH43193.1 - 2.6e-06 27.3 0.1 5.3e-06 26.3 0.1 1.5 1 0 0 1 1 1 1 Barwin family Pollen_allerg_1 PF01357.21 KXH43193.1 - 0.0006 19.8 0.9 0.0011 18.9 0.4 1.7 2 0 0 2 2 2 1 Pollen allergen BNR PF02012.20 KXH43193.1 - 0.059 13.4 0.2 0.19 11.8 0.2 2.0 1 0 0 1 1 1 0 BNR/Asp-box repeat Mo-co_dimer PF03404.16 KXH43193.1 - 0.063 13.3 0.3 1.4 9.0 0.0 2.3 1 1 1 2 2 2 0 Mo-co oxidoreductase dimerisation domain CHB_HEX_C PF03174.13 KXH43193.1 - 0.18 11.8 0.1 0.48 10.5 0.1 1.7 1 0 0 1 1 1 0 Chitobiase/beta-hexosaminidase C-terminal domain DUF2367 PF10164.9 KXH43193.1 - 3.3 8.3 6.3 1.5 9.4 0.3 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2367) WD40 PF00400.32 KXH43194.1 - 3.1e-37 125.9 19.4 8.3e-09 36.0 2.1 7.9 7 1 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXH43194.1 - 4.9e-16 58.8 1.0 0.029 14.7 0.0 6.3 4 2 3 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain PRP4 PF08799.11 KXH43194.1 - 2.1e-13 49.6 3.8 3.8e-13 48.7 3.8 1.5 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like Nbas_N PF15492.6 KXH43194.1 - 0.003 16.9 0.0 0.48 9.7 0.0 2.3 2 0 0 2 2 2 2 Neuroblastoma-amplified sequence, N terminal Ge1_WD40 PF16529.5 KXH43194.1 - 0.0031 16.5 0.0 9.5 5.1 0.0 4.5 1 1 4 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KXH43194.1 - 0.032 13.5 0.0 4.5 6.5 0.0 2.8 2 0 0 2 2 2 0 WD40-like domain Beta_elim_lyase PF01212.21 KXH43195.1 - 2.4e-62 210.9 0.0 3e-62 210.5 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 KXH43195.1 - 2e-05 24.0 0.0 2.7e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 KXH43195.1 - 2.9e-05 23.5 1.4 8e-05 22.1 0.5 1.8 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 KXH43195.1 - 0.014 13.9 0.0 0.031 12.8 0.0 1.4 1 1 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme MFS_1 PF07690.16 KXH43196.1 - 1.1e-27 97.0 18.6 1.5e-27 96.5 18.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH43196.1 - 1.1e-14 54.1 12.7 2.6e-14 53.0 12.7 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_4 PF06779.14 KXH43196.1 - 0.00013 21.4 9.2 0.00013 21.4 9.2 2.0 1 1 1 2 2 2 1 Uncharacterised MFS-type transporter YbfB Saf_2TM PF18303.1 KXH43196.1 - 0.098 12.2 1.8 0.23 11.0 0.1 2.4 3 1 0 3 3 3 0 SAVED-fused 2TM effector domain DUF3382 PF11862.8 KXH43196.1 - 0.1 12.9 4.3 2.3 8.5 0.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3382) CDH-cyt PF16010.5 KXH43198.1 - 1.7e-24 86.5 8.7 1.7e-24 86.5 8.7 1.8 2 0 0 2 2 2 1 Cytochrome domain of cellobiose dehydrogenase DOMON PF03351.17 KXH43198.1 - 6.1e-08 32.9 0.4 1.3e-07 31.8 0.4 1.6 1 0 0 1 1 1 1 DOMON domain DUF2427 PF10348.9 KXH43198.1 - 0.00054 19.7 8.1 0.00054 19.7 8.1 2.5 1 1 1 2 2 2 1 Domain of unknown function (DUF2427) ATP_sub_h PF10775.9 KXH43199.1 - 1.9e-26 91.8 1.1 2.1e-26 91.7 0.4 1.4 2 0 0 2 2 2 1 ATP synthase complex subunit h ATP-synt_F6 PF05511.11 KXH43199.1 - 0.098 13.1 0.0 0.12 12.8 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ATP synthase coupling factor 6 C2 PF00168.30 KXH43200.1 - 8.5e-09 35.6 0.0 1.1e-05 25.7 0.0 2.4 2 0 0 2 2 2 2 C2 domain Baculo_PEP_C PF04513.12 KXH43218.1 - 0.41 10.7 2.3 0.57 10.2 0.7 2.0 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus PikAIV_N PF18605.1 KXH43218.1 - 1.1 8.9 5.9 9.1 6.0 3.0 3.1 2 0 0 2 2 2 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain ATP_transf PF09830.9 KXH43219.1 - 2.4e-14 53.2 0.0 3.8e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 ATP adenylyltransferase DUF898 PF05987.13 KXH43220.1 - 5.5 5.9 10.6 2.4 7.1 3.8 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF898) MFS_1 PF07690.16 KXH43221.1 - 8.8e-29 100.5 35.3 8.8e-29 100.5 35.3 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily TauD PF02668.16 KXH43222.1 - 1e-28 100.9 0.1 1.8e-28 100.1 0.1 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Ank_2 PF12796.7 KXH43222.1 - 7.2e-24 84.2 0.3 1.1e-10 42.0 0.1 4.1 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXH43222.1 - 1.2e-17 63.7 1.6 8.1e-06 26.0 0.0 5.1 4 1 0 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXH43222.1 - 8.6e-16 56.5 4.3 0.095 13.3 0.0 7.2 7 0 0 7 7 7 4 Ankyrin repeat Ank_4 PF13637.6 KXH43222.1 - 2.1e-15 56.8 3.3 8e-08 32.7 0.3 4.9 2 2 4 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 KXH43222.1 - 2.8e-10 40.2 6.9 0.2 12.2 0.0 6.4 6 0 0 6 6 6 3 Ankyrin repeat ERAP1_C PF11838.8 KXH43222.1 - 0.058 12.9 0.2 0.099 12.2 0.2 1.3 1 0 0 1 1 1 0 ERAP1-like C-terminal domain Fungal_trans_2 PF11951.8 KXH43224.1 - 6.1e-12 45.0 0.1 1.2e-11 44.1 0.1 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH43224.1 - 1e-05 25.5 11.3 1.9e-05 24.7 11.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TRP PF06011.12 KXH43225.1 - 1.6e-142 475.3 36.3 2.1e-142 474.8 36.3 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 KXH43225.1 - 1.4e-37 129.2 0.4 2.4e-37 128.4 0.4 1.4 1 0 0 1 1 1 1 ML-like domain Methyltransf_23 PF13489.6 KXH43226.1 - 2.6e-12 46.9 0.0 3.5e-12 46.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH43226.1 - 3.4e-11 43.7 0.0 8.2e-11 42.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH43226.1 - 7.1e-11 42.7 0.0 1.2e-10 42.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH43226.1 - 1.4e-07 32.1 0.0 2.6e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH43226.1 - 9.1e-07 28.8 0.0 1.8e-06 27.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXH43226.1 - 0.003 16.9 0.0 0.016 14.5 0.0 2.0 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family CheR PF01739.18 KXH43226.1 - 0.0043 16.6 0.0 0.024 14.1 0.0 2.0 1 1 1 2 2 2 1 CheR methyltransferase, SAM binding domain MetW PF07021.12 KXH43226.1 - 0.014 15.0 0.1 0.028 14.0 0.1 1.4 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW BMC PF00936.19 KXH43226.1 - 0.034 14.1 0.1 0.069 13.1 0.1 1.5 1 0 0 1 1 1 0 BMC domain FtsJ PF01728.19 KXH43226.1 - 0.09 12.9 0.2 0.97 9.5 0.2 2.3 1 1 0 1 1 1 0 FtsJ-like methyltransferase DUF4483 PF14825.6 KXH43227.1 - 0.011 15.4 0.1 0.014 15.2 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4483) PhoD PF09423.10 KXH43228.1 - 1.3e-38 132.9 2.0 4.8e-38 131.1 1.8 1.9 1 1 0 1 1 1 1 PhoD-like phosphatase Metallophos PF00149.28 KXH43228.1 - 0.007 16.9 0.4 0.013 16.0 0.4 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PhoD_N PF16655.5 KXH43228.1 - 0.0082 16.7 0.1 0.023 15.2 0.1 1.7 1 0 0 1 1 1 1 PhoD-like phosphatase, N-terminal domain Pur_ac_phosph_N PF16656.5 KXH43228.1 - 0.059 13.9 0.1 0.21 12.2 0.1 1.9 2 0 0 2 2 2 0 Purple acid Phosphatase, N-terminal domain Sugar_tr PF00083.24 KXH43229.1 - 9.9e-38 130.1 29.5 1.6e-25 89.9 12.8 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KXH43229.1 - 2.8e-19 69.3 40.6 3e-09 36.3 19.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_holin_2_4 PF16082.5 KXH43229.1 - 0.017 14.8 3.1 0.027 14.2 0.1 2.8 2 1 0 2 2 2 0 Bacteriophage holin family, superfamily II-like COesterase PF00135.28 KXH43230.1 - 1.8e-84 284.5 0.0 1e-75 255.6 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 KXH43230.1 - 1.4e-11 44.6 0.0 2.3e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold MFS_1 PF07690.16 KXH43231.1 - 1.1e-36 126.5 17.8 1.1e-36 126.5 17.8 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF3040 PF11239.8 KXH43231.1 - 0.88 9.9 8.2 0.98 9.7 0.0 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF3040) Abhydrolase_1 PF00561.20 KXH43232.1 - 8e-23 81.4 0.2 4.7e-22 78.9 0.2 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXH43232.1 - 3.9e-20 73.4 0.2 5e-20 73.0 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.14 KXH43232.1 - 1.7e-07 30.2 0.0 4e-06 25.7 0.0 2.1 2 0 0 2 2 2 1 Ndr family Hydrolase_4 PF12146.8 KXH43232.1 - 1.8e-07 30.6 0.0 1.1e-06 28.2 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 QCR10 PF09796.9 KXH43232.1 - 0.012 15.7 0.2 0.049 13.7 0.1 2.0 2 0 0 2 2 2 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) Esterase_phd PF10503.9 KXH43232.1 - 0.025 14.1 0.1 0.23 10.9 0.0 2.3 3 0 0 3 3 3 0 Esterase PHB depolymerase Ins134_P3_kin_N PF17927.1 KXH43232.1 - 0.074 13.5 0.1 0.35 11.3 0.0 1.9 2 0 0 2 2 2 0 Inositol 1,3,4-trisphosphate 5/6-kinase pre-ATP-grasp domain Peptidase_S9 PF00326.21 KXH43232.1 - 0.087 12.3 0.0 0.31 10.5 0.0 2.1 1 1 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_5 PF12695.7 KXH43232.1 - 0.089 12.6 0.0 0.37 10.5 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase family Pax2_C PF12403.8 KXH43232.1 - 0.091 12.8 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 Paired-box protein 2 C terminal FSH1 PF03959.13 KXH43232.1 - 0.14 11.7 0.0 0.7 9.5 0.0 1.9 2 0 0 2 2 2 0 Serine hydrolase (FSH1) bZIP_1 PF00170.21 KXH43233.1 - 0.00078 19.5 4.3 0.0019 18.3 4.3 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KXH43233.1 - 0.0051 16.9 8.0 0.012 15.7 8.0 1.6 1 0 0 1 1 1 1 Basic region leucine zipper DMAP_binding PF06464.11 KXH43233.1 - 0.076 13.8 0.3 0.36 11.6 0.0 2.2 1 1 1 2 2 2 0 DMAP1-binding Domain adh_short PF00106.25 KXH43234.1 - 2.8e-17 62.8 0.2 8.8e-17 61.2 0.2 1.7 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXH43234.1 - 4.1e-10 39.6 0.2 6.9e-10 38.9 0.2 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH43234.1 - 3.9e-05 23.6 0.2 6.1e-05 23.0 0.2 1.3 1 0 0 1 1 1 1 KR domain SPO22 PF08631.10 KXH43234.1 - 0.2 11.1 0.0 0.28 10.6 0.0 1.1 1 0 0 1 1 1 0 Meiosis protein SPO22/ZIP4 like AMP-binding PF00501.28 KXH43236.1 - 5.2e-65 219.7 0.0 1.2e-64 218.5 0.0 1.4 1 1 0 1 1 1 1 AMP-binding enzyme FAD_binding_4 PF01565.23 KXH43236.1 - 1.3e-20 73.5 2.2 2.7e-20 72.5 2.2 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KXH43236.1 - 1e-10 41.5 0.2 2.6e-10 40.2 0.2 1.7 1 0 0 1 1 1 1 Berberine and berberine like p450 PF00067.22 KXH43237.1 - 1e-57 195.9 0.0 1.3e-57 195.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 KR PF08659.10 KXH43238.1 - 6.4e-53 179.3 1.9 1.6e-52 178.1 1.2 2.1 2 0 0 2 2 2 1 KR domain PS-DH PF14765.6 KXH43238.1 - 9.6e-53 179.3 0.0 1.7e-52 178.5 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 KXH43238.1 - 4.1e-45 154.7 0.1 6.2e-45 154.1 0.1 1.3 1 0 0 1 1 1 1 Acyl transferase domain ketoacyl-synt PF00109.26 KXH43238.1 - 1e-39 136.6 0.0 5.8e-32 111.2 0.0 2.7 2 1 1 3 3 3 2 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KXH43238.1 - 8e-35 119.4 0.1 2.5e-34 117.8 0.1 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KXH43238.1 - 4.8e-20 72.1 0.0 1.5e-19 70.5 0.0 2.0 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N_2 PF13602.6 KXH43238.1 - 1.4e-19 71.5 0.1 2.6e-18 67.3 0.0 2.9 3 0 0 3 3 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KXH43238.1 - 1.2e-14 54.4 0.0 4.8e-14 52.5 0.0 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 KXH43238.1 - 8.9e-09 35.1 1.1 2.8e-08 33.5 1.1 1.9 1 0 0 1 1 1 1 short chain dehydrogenase PP-binding PF00550.25 KXH43238.1 - 1.5e-06 28.4 0.0 4.7e-06 26.9 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short_C2 PF13561.6 KXH43238.1 - 0.0011 18.6 0.2 0.0033 17.0 0.2 1.8 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Methyltransf_23 PF13489.6 KXH43238.1 - 0.0057 16.5 0.0 0.014 15.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH43238.1 - 0.018 15.7 0.0 0.37 11.5 0.0 2.8 2 0 0 2 2 2 0 Methyltransferase domain AXE1 PF05448.12 KXH43239.1 - 9.5e-10 37.6 0.0 2.2e-06 26.6 0.0 2.1 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) Hydrolase_4 PF12146.8 KXH43239.1 - 5e-07 29.2 0.0 1e-06 28.2 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KXH43239.1 - 1.4e-05 25.8 0.1 1.6e-05 25.6 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXH43239.1 - 0.00086 19.0 0.0 0.0081 15.8 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KXH43239.1 - 0.0033 16.9 0.0 0.13 11.7 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family BAAT_C PF08840.11 KXH43239.1 - 0.0077 16.2 0.0 0.012 15.6 0.0 1.2 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal FSH1 PF03959.13 KXH43240.1 - 6.8e-27 94.5 0.0 2e-26 93.0 0.0 1.7 1 1 0 1 1 1 1 Serine hydrolase (FSH1) ADH_zinc_N PF00107.26 KXH43241.1 - 1.8e-18 66.7 0.1 2.7e-18 66.2 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KXH43241.1 - 1.7e-16 60.0 0.0 4.5e-16 58.7 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 KXH43241.1 - 1e-07 33.1 0.0 2e-07 32.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Zn_clus PF00172.18 KXH43242.1 - 9.2e-09 35.3 8.9 9.2e-09 35.3 8.9 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ketoacyl-synt PF00109.26 KXH43243.1 - 2.3e-68 230.5 0.0 4.3e-68 229.6 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KXH43243.1 - 2.9e-61 206.5 0.1 7.8e-61 205.1 0.1 1.8 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 KXH43243.1 - 2.7e-52 177.8 0.0 4.8e-52 177.0 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 KXH43243.1 - 1.3e-45 156.3 0.4 2.1e-45 155.6 0.4 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KXH43243.1 - 1.4e-36 125.1 0.2 7.4e-36 122.7 0.2 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KXH43243.1 - 3.7e-16 59.6 0.1 3.8e-15 56.3 0.1 2.4 1 1 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N PF00107.26 KXH43243.1 - 3.1e-11 43.4 0.4 1.9e-10 40.8 0.1 2.4 2 0 0 2 2 2 1 Zinc-binding dehydrogenase adh_short PF00106.25 KXH43243.1 - 1.6e-08 34.2 0.0 5.5e-08 32.5 0.0 1.9 1 0 0 1 1 1 1 short chain dehydrogenase ADH_N PF08240.12 KXH43243.1 - 3.6e-05 23.6 0.2 0.00011 22.1 0.2 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain adh_short_C2 PF13561.6 KXH43243.1 - 7.6e-05 22.4 0.5 0.00023 20.8 0.0 2.1 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase PP-binding PF00550.25 KXH43243.1 - 0.00044 20.5 0.0 0.0014 18.9 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_zinc_N_2 PF13602.6 KXH43243.1 - 0.029 15.4 0.2 0.6 11.2 0.0 3.3 4 0 0 4 4 3 0 Zinc-binding dehydrogenase ACP_syn_III PF08545.10 KXH43243.1 - 0.049 13.5 0.5 0.22 11.4 0.0 2.4 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.23 KXH43243.1 - 0.063 12.6 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Thiolase, N-terminal domain TusA PF01206.17 KXH43243.1 - 0.12 12.2 0.0 24 4.9 0.0 3.0 3 0 0 3 3 3 0 Sulfurtransferase TusA MBOAT_2 PF13813.6 KXH43244.1 - 8.5e-20 70.8 2.2 8.5e-20 70.8 2.2 2.1 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family TFIIF_beta PF02270.15 KXH43244.1 - 0.084 13.0 0.5 8.1 6.7 0.0 2.5 2 0 0 2 2 2 0 TFIIF, beta subunit HTH domain p450 PF00067.22 KXH43245.1 - 1.4e-59 202.0 0.0 1.8e-59 201.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 GFA PF04828.14 KXH43246.1 - 9.8e-11 41.8 0.1 1.4e-10 41.3 0.1 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme MFS_1 PF07690.16 KXH43247.1 - 9.3e-22 77.4 30.4 9.3e-22 77.4 30.4 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH43247.1 - 3.9e-07 29.3 5.6 3.9e-07 29.3 5.6 2.0 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_3 PF05977.13 KXH43247.1 - 0.0035 15.8 4.8 0.0048 15.3 0.4 2.3 1 1 1 2 2 2 1 Transmembrane secretion effector LapA_dom PF06305.11 KXH43247.1 - 0.23 11.3 6.0 0.61 10.0 0.0 3.3 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain Dynactin_p62 PF05502.13 KXH43247.1 - 0.39 9.4 0.2 0.54 9.0 0.2 1.1 1 0 0 1 1 1 0 Dynactin p62 family FSH1 PF03959.13 KXH43248.1 - 1.3e-28 100.1 0.0 2e-27 96.3 0.0 2.3 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 KXH43248.1 - 1.9e-06 28.7 4.1 2.3e-06 28.4 4.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 KXH43248.1 - 0.0087 15.9 0.2 0.19 11.5 0.8 2.4 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase MFS_1 PF07690.16 KXH43249.1 - 8.8e-40 136.7 83.3 1.6e-37 129.3 51.5 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KXH43249.1 - 5.1e-14 51.6 15.3 7e-14 51.2 15.3 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) p450 PF00067.22 KXH43251.1 - 5.2e-59 200.2 0.0 5.9e-59 200.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 GerA PF03323.13 KXH43251.1 - 0.23 9.9 0.2 0.33 9.4 0.2 1.1 1 0 0 1 1 1 0 Bacillus/Clostridium GerA spore germination protein p450 PF00067.22 KXH43252.1 - 1.1e-34 120.1 0.0 1.4e-34 119.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 SnoaL_2 PF12680.7 KXH43253.1 - 0.018 15.7 0.0 0.15 12.7 0.0 2.1 2 0 0 2 2 2 0 SnoaL-like domain DUF4440 PF14534.6 KXH43253.1 - 0.095 13.1 0.1 0.34 11.3 0.1 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4440) Epimerase PF01370.21 KXH43254.1 - 4.6e-08 32.8 0.2 3.9e-07 29.8 0.2 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KXH43254.1 - 0.00029 20.8 0.1 0.00049 20.0 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KXH43254.1 - 0.00034 20.3 0.2 0.00051 19.7 0.2 1.3 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 KXH43254.1 - 0.011 14.8 0.0 0.083 11.9 0.1 2.0 1 1 1 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KXH43254.1 - 0.059 12.8 0.1 0.15 11.4 0.1 1.7 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Sacchrp_dh_NADP PF03435.18 KXH43254.1 - 0.09 13.0 0.1 0.18 12.0 0.1 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Polysacc_synt_2 PF02719.15 KXH43254.1 - 0.1 11.7 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 KXH43254.1 - 0.11 11.6 0.1 0.24 10.5 0.1 1.6 1 1 0 1 1 1 0 Male sterility protein RTA1 PF04479.13 KXH43255.1 - 9.8e-45 152.7 9.3 1.9e-44 151.8 9.3 1.3 1 0 0 1 1 1 1 RTA1 like protein Glyco_hydro_43 PF04616.14 KXH43256.1 - 9.8e-35 120.3 5.5 1.4e-34 119.7 5.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 KXH43256.1 - 8.3e-21 74.6 0.0 1.2e-20 74.1 0.0 1.2 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain UDPG_MGDP_dh_N PF03721.14 KXH43257.1 - 3.5e-49 166.9 0.0 3.4e-35 121.3 0.0 2.9 2 1 1 3 3 3 2 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.19 KXH43257.1 - 1.1e-30 105.6 0.0 2.2e-30 104.7 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.15 KXH43257.1 - 1.5e-22 80.0 0.0 1.1e-17 64.3 0.0 3.5 3 0 0 3 3 3 2 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain NAD_binding_2 PF03446.15 KXH43257.1 - 0.041 14.1 0.0 0.86 9.8 0.0 2.7 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Sacchrp_dh_NADP PF03435.18 KXH43257.1 - 0.047 13.9 0.0 0.25 11.6 0.0 2.3 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Glyco_hydro_12 PF01670.16 KXH43258.1 - 7.1e-14 52.3 8.9 2.7e-11 43.9 1.7 2.1 1 1 1 2 2 2 2 Glycosyl hydrolase family 12 Glycos_transf_2 PF00535.26 KXH43260.1 - 6.1e-20 71.7 0.0 9.3e-20 71.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 KXH43260.1 - 7.2e-18 64.7 0.0 1.2e-17 63.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_trans_2_3 PF13632.6 KXH43260.1 - 6.1e-17 62.2 0.3 6.1e-17 62.2 0.3 2.5 2 1 1 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KXH43260.1 - 2.6e-12 47.1 0.0 3.6e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Cellulose_synt PF03552.14 KXH43260.1 - 1.9e-05 23.4 0.7 0.005 15.4 0.2 2.3 2 0 0 2 2 2 2 Cellulose synthase Glyoxalase PF00903.25 KXH43261.1 - 2.3e-10 40.8 0.0 3e-10 40.4 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 KXH43261.1 - 0.0067 17.2 0.0 0.012 16.4 0.0 1.4 1 1 0 1 1 1 1 Glyoxalase-like domain HET PF06985.11 KXH43264.1 - 1.2e-19 71.1 0.2 3.2e-19 69.7 0.0 1.8 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Glyco_hydro_43 PF04616.14 KXH43265.1 - 2e-50 171.7 0.5 2.5e-50 171.4 0.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 CBM_6 PF03422.15 KXH43265.1 - 6.8e-34 116.9 0.4 1.4e-33 115.8 0.4 1.6 1 0 0 1 1 1 1 Carbohydrate binding module (family 6) DUF5010_C PF18099.1 KXH43265.1 - 4.6e-08 33.2 0.2 8.5e-08 32.3 0.2 1.4 1 0 0 1 1 1 1 DUF5010 C-terminal domain Glyco_hydro_32N PF00251.20 KXH43265.1 - 0.00044 19.9 0.2 0.00082 19.0 0.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain ADH_N PF08240.12 KXH43266.1 - 2e-14 53.4 0.0 3.5e-14 52.6 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXH43266.1 - 3.1e-08 33.6 0.4 1.9e-07 31.1 0.4 2.0 1 1 0 1 1 1 1 Zinc-binding dehydrogenase HI0933_like PF03486.14 KXH43266.1 - 0.00078 18.3 0.2 0.001 17.9 0.2 1.1 1 0 0 1 1 1 1 HI0933-like protein Glu_dehyd_C PF16912.5 KXH43266.1 - 0.001 18.6 0.0 0.0018 17.8 0.0 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus FAD_binding_2 PF00890.24 KXH43266.1 - 0.0028 16.8 0.9 0.004 16.3 0.9 1.2 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 KXH43266.1 - 0.0061 15.9 0.1 0.011 15.0 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 KXH43266.1 - 0.22 10.7 0.2 0.32 10.2 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain Aldo_ket_red PF00248.21 KXH43267.1 - 1.2e-62 211.8 0.0 1.4e-62 211.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family HEV_ORF1 PF02444.16 KXH43268.1 - 0.02 15.4 0.2 0.047 14.3 0.0 1.7 2 0 0 2 2 2 0 Hepatitis E virus ORF-2 (Putative capsid protein) HET PF06985.11 KXH43269.1 - 7.8e-23 81.4 0.0 1.3e-22 80.7 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) GMC_oxred_C PF05199.13 KXH43270.1 - 3.6e-30 105.4 0.0 6.6e-30 104.5 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 KXH43270.1 - 5.9e-27 94.8 0.0 3.2e-24 85.8 0.0 2.4 2 1 0 2 2 2 2 GMC oxidoreductase Pyr_redox_2 PF07992.14 KXH43270.1 - 0.00038 19.8 0.0 0.00092 18.5 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXH43270.1 - 0.0038 17.4 1.3 0.0057 16.9 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KXH43270.1 - 0.011 14.8 0.0 0.021 13.9 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 KXH43270.1 - 0.011 14.8 0.0 0.018 14.1 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_3 PF01494.19 KXH43270.1 - 0.057 12.7 0.2 0.088 12.0 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 KXH43270.1 - 0.11 11.1 0.1 0.19 10.4 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein Fimbrial PF00419.20 KXH43270.1 - 0.14 12.4 0.1 0.34 11.2 0.0 1.7 2 0 0 2 2 2 0 Fimbrial protein CFEM PF05730.11 KXH43271.1 - 2.8e-11 43.3 10.1 6e-11 42.3 10.1 1.6 1 0 0 1 1 1 1 CFEM domain Methyltransf_23 PF13489.6 KXH43272.1 - 8.6e-23 81.0 0.0 1.3e-22 80.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH43272.1 - 2e-14 54.1 0.0 8.6e-14 52.0 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH43272.1 - 1.7e-12 47.8 0.0 3.9e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH43272.1 - 1.5e-11 44.9 0.0 6.5e-11 42.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH43272.1 - 9.1e-10 38.5 0.0 2.2e-08 34.0 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXH43272.1 - 1.6e-08 34.1 0.0 2.4e-07 30.3 0.0 2.2 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KXH43272.1 - 0.0002 21.0 0.0 0.0021 17.6 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_4 PF02390.17 KXH43272.1 - 0.00024 20.6 0.1 0.0041 16.6 0.0 2.5 3 0 0 3 3 3 1 Putative methyltransferase Methyltransf_16 PF10294.9 KXH43272.1 - 0.0034 17.1 0.0 0.0058 16.4 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase ANAPC4_WD40 PF12894.7 KXH43273.1 - 2.5e-10 40.5 0.0 2.2e-05 24.7 0.0 3.7 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KXH43273.1 - 4e-05 24.3 4.3 0.089 13.7 0.1 4.6 5 0 0 5 5 5 2 WD domain, G-beta repeat Ge1_WD40 PF16529.5 KXH43273.1 - 0.0036 16.3 0.0 0.0067 15.4 0.0 1.4 1 0 0 1 1 1 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KXH43273.1 - 0.054 12.8 0.0 0.093 12.0 0.0 1.3 1 0 0 1 1 1 0 WD40-like domain PD40 PF07676.12 KXH43273.1 - 0.11 12.5 0.6 0.95 9.5 0.0 2.7 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Lactamase_B_2 PF12706.7 KXH43274.1 - 0.0011 18.5 0.2 0.0018 17.8 0.2 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KXH43274.1 - 0.0066 16.3 0.2 0.02 14.8 0.2 1.9 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Radial_spoke PF04712.12 KXH43274.1 - 0.14 11.1 0.0 0.22 10.4 0.0 1.3 1 0 0 1 1 1 0 Radial spokehead-like protein Fungal_trans_2 PF11951.8 KXH43275.1 - 6.8e-29 100.8 0.1 8.4e-29 100.5 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH43275.1 - 2.7e-08 33.8 5.9 2.7e-08 33.8 5.9 2.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 KXH43276.1 - 2.7e-34 118.7 32.3 2.7e-34 118.7 32.3 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH43276.1 - 1.9e-08 33.6 11.1 1.9e-08 33.6 11.1 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KXH43276.1 - 2.4e-08 32.9 0.8 4.3e-08 32.1 0.8 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF3523 PF12037.8 KXH43276.1 - 0.22 10.9 0.3 0.4 10.0 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3523) Oxidored_q5_N PF01059.17 KXH43276.1 - 9.7 6.3 8.0 0.44 10.7 1.1 2.4 2 1 1 3 3 3 0 NADH-ubiquinone oxidoreductase chain 4, amino terminus SIS PF01380.22 KXH43277.1 - 3.4e-12 46.3 0.0 5.6e-12 45.6 0.0 1.4 1 0 0 1 1 1 1 SIS domain ALO PF04030.14 KXH43278.1 - 7e-86 288.3 0.5 9e-86 287.9 0.5 1.1 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 KXH43278.1 - 2.4e-28 98.6 0.0 4.2e-28 97.8 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Aldo_ket_red PF00248.21 KXH43279.1 - 2.4e-51 174.7 0.0 3.2e-51 174.3 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family DASH_Spc34 PF08657.10 KXH43280.1 - 0.022 14.6 0.5 0.035 13.9 0.5 1.2 1 0 0 1 1 1 0 DASH complex subunit Spc34 Mycoplasma_p37 PF06646.11 KXH43280.1 - 0.19 10.9 0.2 0.29 10.3 0.2 1.2 1 0 0 1 1 1 0 High affinity transport system protein p37 ERG4_ERG24 PF01222.17 KXH43281.1 - 1.9e-151 504.7 4.9 2.2e-151 504.5 4.9 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 KXH43281.1 - 0.00042 19.9 1.0 0.00083 18.9 0.2 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) Peptidase_M28 PF04389.17 KXH43282.1 - 2.7e-42 144.7 0.0 4.6e-42 144.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KXH43282.1 - 8.9e-11 41.7 0.2 3.1e-10 40.0 0.1 2.0 2 0 0 2 2 2 1 PA domain Peptidase_M20 PF01546.28 KXH43282.1 - 1.7e-06 27.9 0.0 2.9e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Glyco_hydro_61 PF03443.14 KXH43284.1 - 3.4e-63 213.3 1.3 4.1e-63 213.0 1.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF5624 PF18538.1 KXH43284.1 - 0.0035 17.4 0.0 0.0054 16.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF5624) Glyco_hydro_28 PF00295.17 KXH43285.1 - 1.9e-122 408.4 23.4 2.1e-122 408.2 23.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Cu-oxidase_3 PF07732.15 KXH43286.1 - 8.4e-40 135.5 1.7 8.4e-40 135.5 1.7 2.1 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KXH43286.1 - 1.1e-36 125.6 8.8 9.3e-35 119.3 0.3 3.3 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 KXH43286.1 - 2.2e-30 105.9 1.1 2.2e-28 99.4 0.0 3.3 3 1 0 3 3 3 1 Multicopper oxidase Phosphoesterase PF04185.14 KXH43287.1 - 2.5e-35 122.3 2.9 5e-33 114.8 1.4 3.0 1 1 1 2 2 2 2 Phosphoesterase family VIT1 PF01988.19 KXH43288.1 - 9.6e-64 215.2 0.3 1.2e-63 214.9 0.3 1.1 1 0 0 1 1 1 1 VIT family adh_short PF00106.25 KXH43289.1 - 1.4e-23 83.4 0.1 2.1e-23 82.8 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXH43289.1 - 4.2e-14 52.7 0.6 5.8e-14 52.2 0.6 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH43289.1 - 5.8e-09 36.1 0.3 1.1e-08 35.2 0.3 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KXH43289.1 - 4.5e-05 23.0 0.0 8.8e-05 22.1 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXH43289.1 - 0.00029 20.4 0.0 0.00043 19.8 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KXH43289.1 - 0.0048 16.8 0.6 0.0066 16.4 0.6 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Peptidase_S28 PF05577.12 KXH43290.1 - 9.3e-43 146.6 1.2 6.3e-42 143.9 1.2 1.9 1 1 0 1 1 1 1 Serine carboxypeptidase S28 DUF2920 PF11144.8 KXH43290.1 - 0.00082 18.6 0.0 0.0012 18.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2920) Peptidase_S37 PF05576.11 KXH43290.1 - 0.026 13.2 0.9 0.53 8.9 0.0 2.3 2 0 0 2 2 2 0 PS-10 peptidase S37 NDUF_B7 PF05676.13 KXH43291.1 - 2.2e-29 100.9 3.1 2.6e-29 100.7 3.1 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.10 KXH43291.1 - 0.0012 18.8 1.4 0.0014 18.6 0.9 1.4 1 1 1 2 2 2 1 Cytochrome c oxidase biogenesis protein Cmc1 like Voltage_CLC PF00654.20 KXH43292.1 - 1.1e-85 287.9 17.1 1.1e-85 287.9 17.1 1.8 2 1 1 3 3 3 1 Voltage gated chloride channel CBS PF00571.28 KXH43292.1 - 0.00047 20.5 0.1 0.0013 19.1 0.1 1.8 1 0 0 1 1 1 1 CBS domain DUF2062 PF09835.9 KXH43292.1 - 0.0016 18.3 0.3 0.0016 18.3 0.3 2.5 3 0 0 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2062) CnrY PF17524.2 KXH43292.1 - 0.12 12.5 1.4 6.6 7.0 0.0 3.2 3 0 0 3 3 3 0 Anti-sigma factor CnrY LacI PF00356.21 KXH43292.1 - 0.15 11.9 5.2 0.39 10.6 0.3 2.4 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family GTP_cyclohydro2 PF00925.20 KXH43294.1 - 5.8e-61 204.8 0.0 7.9e-61 204.4 0.0 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase II Hexapep PF00132.24 KXH43295.1 - 6.9e-09 35.1 6.7 6.8e-05 22.4 3.9 5.0 3 1 2 5 5 5 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KXH43295.1 - 2.1e-05 24.2 0.2 0.17 11.7 0.0 3.0 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 KXH43295.1 - 0.25 10.3 0.0 0.35 9.8 0.0 1.1 1 0 0 1 1 1 0 L-fucokinase Meth_synt_2 PF01717.18 KXH43296.1 - 3.2e-07 29.9 0.0 5e-06 26.0 0.0 2.1 2 0 0 2 2 2 1 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 KXH43296.1 - 0.075 12.5 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Cobalamin-independent synthase, N-terminal domain F-box-like PF12937.7 KXH43297.1 - 1.6e-08 34.3 6.1 1.7e-08 34.2 3.5 2.4 2 1 0 2 2 2 1 F-box-like F-box PF00646.33 KXH43297.1 - 0.0046 16.8 5.2 0.13 12.2 5.2 2.8 2 1 0 2 2 2 1 F-box domain F-box_5 PF18511.1 KXH43297.1 - 0.11 12.1 0.1 0.98 9.0 0.0 2.2 2 0 0 2 2 2 0 F-box PRELI PF04707.14 KXH43298.1 - 4.2e-19 68.9 0.0 9.1e-16 58.1 0.0 2.1 2 0 0 2 2 2 2 PRELI-like family PCRF PF03462.18 KXH43299.1 - 9.8e-50 169.1 0.3 3.6e-49 167.3 0.0 2.1 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 KXH43299.1 - 9.5e-34 115.8 2.0 2.8e-33 114.3 2.0 1.8 1 0 0 1 1 1 1 RF-1 domain PDEase_I_N PF08499.12 KXH43299.1 - 0.096 12.5 0.9 22 5.0 0.1 2.7 2 0 0 2 2 2 0 3'5'-cyclic nucleotide phosphodiesterase N-terminal GST_N_3 PF13417.6 KXH43301.1 - 1.7e-15 57.2 0.0 3.3e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KXH43301.1 - 4.7e-13 49.3 0.0 9.7e-13 48.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KXH43301.1 - 5.1e-10 39.5 0.0 8.1e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KXH43301.1 - 7.3e-06 25.9 0.6 1.8e-05 24.7 0.6 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KXH43301.1 - 0.00024 21.2 0.0 0.00046 20.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 KXH43301.1 - 0.0044 17.3 0.1 0.0096 16.2 0.0 1.6 2 0 0 2 2 2 1 Outer mitochondrial membrane transport complex protein GST_C_3 PF14497.6 KXH43301.1 - 0.0099 16.1 0.0 0.021 15.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 KXH43301.1 - 0.053 14.3 0.0 0.11 13.3 0.0 1.6 1 1 0 1 1 1 0 Glutathione S-transferase N-terminal domain Ifi-6-16 PF06140.13 KXH43303.1 - 0.0023 17.8 7.3 0.27 11.2 2.2 2.2 2 0 0 2 2 2 2 Interferon-induced 6-16 family Ifi-6-16 PF06140.13 KXH43304.1 - 1.1e-08 34.8 0.0 1.6e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Interferon-induced 6-16 family DUF883 PF05957.13 KXH43304.1 - 0.0057 17.2 0.1 0.057 14.0 0.0 2.0 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF883) Flagellar_rod PF05149.12 KXH43304.1 - 0.1 12.0 0.0 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 Paraflagellar rod protein RPA43_OB PF17875.1 KXH43305.1 - 1.6e-34 119.2 0.1 1.6e-34 119.2 0.1 4.0 2 1 0 2 2 2 1 RPA43 OB domain in RNA Pol I SHS2_Rpb7-N PF03876.17 KXH43305.1 - 1.3e-06 28.7 0.0 2.4e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 BRD4_CDT PF17105.5 KXH43305.1 - 0.18 11.4 1.5 0.64 9.7 1.5 1.9 1 0 0 1 1 1 0 C-terminal domain of bromodomain protein 4 Macoilin PF09726.9 KXH43305.1 - 1.2 7.7 14.9 1.5 7.3 14.9 1.1 1 0 0 1 1 1 0 Macoilin family LAP1C PF05609.12 KXH43305.1 - 2.9 6.9 19.6 4.1 6.4 19.6 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Sugar_tr PF00083.24 KXH43306.1 - 3.6e-89 299.7 7.2 5.8e-89 299.0 7.2 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter NmrA PF05368.13 KXH43306.1 - 1.2e-34 119.9 0.1 1.9e-34 119.3 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family MFS_1 PF07690.16 KXH43306.1 - 1.5e-28 99.7 20.7 1.5e-28 99.7 20.7 2.3 1 1 1 2 2 2 1 Major Facilitator Superfamily NAD_binding_10 PF13460.6 KXH43306.1 - 7.5e-11 42.2 0.0 3e-10 40.3 0.0 2.0 1 1 0 1 1 1 1 NAD(P)H-binding TRI12 PF06609.13 KXH43306.1 - 1.1e-08 33.9 3.8 2.5e-08 32.8 3.8 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) 3Beta_HSD PF01073.19 KXH43306.1 - 0.00033 19.8 0.1 0.00056 19.0 0.1 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KXH43306.1 - 0.00087 18.8 0.0 0.0013 18.2 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KXH43306.1 - 0.0012 18.3 0.0 0.0033 16.9 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 KXH43306.1 - 0.0032 17.9 0.1 0.0089 16.5 0.0 1.8 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain PTH2 PF01981.16 KXH43306.1 - 0.038 14.3 0.0 11 6.3 0.0 2.4 2 0 0 2 2 2 0 Peptidyl-tRNA hydrolase PTH2 KR PF08659.10 KXH43306.1 - 0.055 13.4 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 KR domain TrkA_N PF02254.18 KXH43306.1 - 0.084 13.1 0.2 0.2 11.9 0.2 1.6 1 0 0 1 1 1 0 TrkA-N domain Glu_dehyd_C PF16912.5 KXH43306.1 - 0.089 12.3 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus Asp_Glu_race PF01177.22 KXH43307.1 - 0.00012 22.1 0.0 0.00042 20.2 0.0 1.9 1 1 0 1 1 1 1 Asp/Glu/Hydantoin racemase Actin PF00022.19 KXH43308.1 - 4.6e-111 371.3 0.0 2.9e-110 368.7 0.0 1.8 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 KXH43308.1 - 0.027 13.3 0.0 0.22 10.3 0.0 2.1 1 1 0 1 1 1 0 MreB/Mbl protein Actin_micro PF17003.5 KXH43308.1 - 0.049 12.8 0.0 0.28 10.3 0.0 2.0 2 0 0 2 2 2 0 Putative actin-like family Pkinase PF00069.25 KXH43309.1 - 2.1e-63 214.2 0.0 2.7e-63 213.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXH43309.1 - 8.3e-31 107.2 0.0 1.2e-30 106.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXH43309.1 - 0.048 13.0 0.0 0.081 12.2 0.0 1.3 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 KXH43309.1 - 0.11 12.4 0.0 0.4 10.6 0.0 1.7 1 1 0 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KXH43309.1 - 0.12 11.3 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Ribosomal_S24e PF01282.19 KXH43310.1 - 8.4e-35 118.6 0.0 1.6e-34 117.7 0.0 1.5 1 1 0 1 1 1 1 Ribosomal protein S24e Methyltransf_16 PF10294.9 KXH43311.1 - 1.2e-17 64.2 0.0 1.9e-17 63.5 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 KXH43311.1 - 0.00087 19.2 0.0 0.0014 18.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KXH43311.1 - 0.00091 19.0 0.0 0.0019 18.0 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 KXH43311.1 - 0.0018 18.9 0.0 0.0049 17.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KXH43311.1 - 0.0033 16.9 0.0 0.0052 16.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KXH43311.1 - 0.011 15.4 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_12 PF08242.12 KXH43311.1 - 0.059 14.1 0.0 0.12 13.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain DUF938 PF06080.12 KXH43311.1 - 0.11 12.2 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_31 PF13847.6 KXH43311.1 - 0.14 12.0 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.16 KXH43311.1 - 0.14 11.9 0.0 0.23 11.2 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Activator_LAG-3 PF11498.8 KXH43312.1 - 0.014 14.4 0.3 0.018 14.1 0.3 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Pro_isomerase PF00160.21 KXH43313.1 - 4.7e-34 118.0 0.0 8.2e-34 117.2 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 KXH43313.1 - 2.8e-15 55.9 0.0 4.7e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RR_TM4-6 PF06459.12 KXH43313.1 - 0.9 9.3 4.4 1.7 8.4 4.4 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Zn_clus PF00172.18 KXH43314.1 - 1.5e-08 34.6 5.1 2.2e-08 34.1 5.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Apc13p PF05839.11 KXH43316.1 - 4.7e-18 65.2 0.8 5.1e-18 65.1 0.8 1.0 1 0 0 1 1 1 1 Apc13p protein ZZ PF00569.17 KXH43320.1 - 6.3 6.7 5.7 3.1 7.7 0.9 2.5 3 0 0 3 3 3 0 Zinc finger, ZZ type AA_permease_2 PF13520.6 KXH43321.1 - 1.2e-42 146.3 35.4 1.6e-42 145.9 35.4 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXH43321.1 - 1.1e-19 70.5 36.1 1.3e-18 66.9 36.1 2.1 1 1 0 1 1 1 1 Amino acid permease DUF4538 PF15061.6 KXH43321.1 - 4.9 7.0 5.0 1.9 8.3 1.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4538) Ribosomal_L4 PF00573.22 KXH43322.1 - 1e-32 113.4 0.6 1.4e-32 113.0 0.6 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 KXH43322.1 - 1.1e-26 92.7 1.8 1.1e-26 92.7 1.8 1.8 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain Aminotran_1_2 PF00155.21 KXH43323.1 - 1.1e-07 31.4 0.0 1.4e-05 24.5 0.0 2.2 2 0 0 2 2 2 2 Aminotransferase class I and II FAT PF02259.23 KXH43324.1 - 4.7e-71 239.8 6.2 1.3e-70 238.4 6.2 1.8 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.27 KXH43324.1 - 3.4e-35 122.1 0.1 9.2e-35 120.6 0.1 1.8 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 KXH43324.1 - 4e-07 29.8 0.2 1.1e-06 28.3 0.2 1.9 1 0 0 1 1 1 1 FATC domain TPR_2 PF07719.17 KXH43324.1 - 0.042 14.0 2.2 5.4 7.4 0.2 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat HEAT_EZ PF13513.6 KXH43324.1 - 0.049 14.2 0.2 19 5.9 0.0 5.0 5 0 0 5 5 5 0 HEAT-like repeat AAA_32 PF13654.6 KXH43324.1 - 0.084 11.6 1.7 0.24 10.1 0.0 2.4 3 0 0 3 3 3 0 AAA domain TPR_8 PF13181.6 KXH43324.1 - 0.2 12.0 4.4 0.23 11.8 0.4 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Urb2 PF10441.9 KXH43324.1 - 0.3 11.0 7.0 3.1 7.7 0.0 5.1 6 0 0 6 6 6 0 Urb2/Npa2 family RPN6_N PF18055.1 KXH43324.1 - 0.5 10.7 3.9 4.3 7.7 0.0 4.3 4 0 0 4 4 4 0 26S proteasome regulatory subunit RPN6 N-terminal domain TPR_1 PF00515.28 KXH43324.1 - 3.3 7.7 6.9 21 5.2 0.2 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat GGACT PF06094.12 KXH43325.1 - 1.9e-17 64.0 0.1 2.4e-17 63.6 0.1 1.2 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like DUF2870 PF11069.8 KXH43325.1 - 0.068 13.6 0.1 0.12 12.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2870) Glyco_hydro_61 PF03443.14 KXH43326.1 - 0.00041 20.3 0.2 0.00082 19.4 0.2 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF3433 PF11915.8 KXH43327.1 - 8.2e-40 135.2 19.7 1.8e-24 86.0 1.2 4.3 5 0 0 5 5 5 2 Protein of unknown function (DUF3433) PIG-Y PF15159.6 KXH43327.1 - 1.7 9.6 6.8 0.28 12.1 1.4 2.6 2 0 0 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y FAD_binding_3 PF01494.19 KXH43328.1 - 6.4e-42 144.0 0.0 9.5e-42 143.5 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KXH43328.1 - 8.4e-07 29.1 0.0 1.8e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXH43328.1 - 1.5e-05 24.7 0.0 0.00016 21.4 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXH43328.1 - 5e-05 22.7 0.0 0.00011 21.5 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXH43328.1 - 0.0006 20.3 0.0 0.0016 19.0 0.0 1.7 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXH43328.1 - 0.0007 18.4 0.0 0.0011 17.8 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.17 KXH43328.1 - 0.0018 17.6 0.0 0.0029 16.9 0.0 1.2 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 KXH43328.1 - 0.0021 17.2 0.0 0.0035 16.4 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KXH43328.1 - 0.0033 16.7 0.0 0.0057 16.0 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXH43328.1 - 0.0053 15.9 0.0 0.0079 15.3 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.24 KXH43328.1 - 0.0095 15.3 0.1 1 8.6 0.0 2.7 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 KXH43328.1 - 0.051 12.9 0.0 0.12 11.7 0.0 1.6 1 1 0 1 1 1 0 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KXH43328.1 - 0.17 10.7 0.0 0.57 9.0 0.0 1.8 2 0 0 2 2 2 0 Tryptophan halogenase ApbA PF02558.16 KXH43328.1 - 0.18 11.4 0.0 0.32 10.6 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Ferritin_2 PF13668.6 KXH43329.1 - 4e-40 137.1 0.7 5.7e-40 136.7 0.7 1.2 1 0 0 1 1 1 1 Ferritin-like domain RNB PF00773.19 KXH43330.1 - 1.7e-81 274.1 0.0 2.9e-81 273.3 0.0 1.4 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 KXH43330.1 - 9e-26 89.7 0.0 2.4e-25 88.3 0.0 1.8 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Dis3l2_C_term PF17877.1 KXH43330.1 - 9.3e-26 90.0 0.0 3.2e-25 88.3 0.0 2.0 1 0 0 1 1 1 1 DIS3-like exonuclease 2 C terminal CSD2 PF17876.1 KXH43330.1 - 3.7e-06 27.0 0.0 0.017 15.3 0.0 2.7 2 0 0 2 2 2 2 Cold shock domain Rrp44_CSD1 PF17216.3 KXH43330.1 - 0.0043 16.8 0.0 0.0043 16.8 0.0 1.7 2 0 0 2 2 2 1 Rrp44-like cold shock domain DUF4239 PF14023.6 KXH43330.1 - 0.027 14.2 0.5 0.056 13.2 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) GLE1 PF07817.13 KXH43331.1 - 3.9e-63 213.0 0.0 6.7e-63 212.2 0.0 1.3 1 0 0 1 1 1 1 GLE1-like protein YabA PF06156.13 KXH43331.1 - 0.86 10.3 3.2 1.9 9.2 1.1 2.3 2 1 0 2 2 2 0 Initiation control protein YabA DUF1640 PF07798.11 KXH43331.1 - 5.6 7.0 9.3 92 3.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) Syntaxin-6_N PF09177.11 KXH43332.1 - 3e-25 88.6 0.0 8.8e-25 87.1 0.0 1.7 2 0 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.19 KXH43332.1 - 0.0027 17.7 0.4 0.0049 16.8 0.4 1.5 1 0 0 1 1 1 1 SNARE domain TBCA PF02970.16 KXH43332.1 - 0.12 12.7 1.8 0.57 10.5 0.1 2.7 3 1 0 3 3 3 0 Tubulin binding cofactor A ATG16 PF08614.11 KXH43332.1 - 0.33 11.1 5.3 1.2 9.3 0.4 2.5 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) Pox_EPC_I2-L1 PF12575.8 KXH43332.1 - 1.2 9.4 3.3 66 3.8 1.3 3.0 3 0 0 3 3 3 0 Poxvirus entry protein complex L1 and I2 GCIP PF13324.6 KXH43332.1 - 4.2 6.9 6.0 7.1 6.1 5.4 1.8 1 1 0 1 1 1 0 Grap2 and cyclin-D-interacting Methyltransf_32 PF13679.6 KXH43333.1 - 1.6e-20 73.7 0.0 3.3e-20 72.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Melibiase_2_C PF17450.2 KXH43334.1 - 0.029 14.6 0.1 0.049 13.9 0.1 1.4 1 0 0 1 1 1 0 Alpha galactosidase A C-terminal beta sandwich domain ACT_7 PF13840.6 KXH43336.1 - 1.3e-22 79.3 0.4 7.6e-20 70.5 0.1 2.4 2 0 0 2 2 2 2 ACT domain UPF0029 PF01205.19 KXH43337.1 - 5.2e-33 113.5 0.0 7.9e-33 112.9 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.22 KXH43337.1 - 2.6e-06 27.7 0.0 1e-05 25.8 0.0 1.9 1 1 0 1 1 1 1 RWD domain HET PF06985.11 KXH43338.1 - 2.6e-23 83.0 0.0 1.5e-22 80.6 0.0 2.2 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) RabGAP-TBC PF00566.18 KXH43340.1 - 3.1e-37 128.3 3.2 8e-37 127.0 3.2 1.7 1 1 0 1 1 1 1 Rab-GTPase-TBC domain PH_RBD PF12068.8 KXH43340.1 - 3.6e-08 33.1 0.0 0.0017 17.8 0.0 3.2 3 0 0 3 3 3 2 Rab-binding domain (RBD) Mso1_Sec1_bdg PF14475.6 KXH43341.1 - 5.1e-20 70.8 0.1 8.8e-20 70.0 0.1 1.4 1 0 0 1 1 1 1 Sec1-binding region of Mso1 Ribosomal_L28e PF01778.17 KXH43342.1 - 9.7e-38 129.5 0.9 2e-37 128.5 0.9 1.5 1 0 0 1 1 1 1 Ribosomal L28e protein family Mak16 PF04874.14 KXH43342.1 - 1.2e-29 102.9 15.2 1.2e-29 102.9 15.2 2.5 2 0 0 2 2 2 1 Mak16 protein C-terminal region BUD22 PF09073.10 KXH43342.1 - 5.7e-06 25.9 20.0 7.4e-06 25.6 20.0 1.1 1 0 0 1 1 1 1 BUD22 TFIIF_alpha PF05793.12 KXH43342.1 - 0.0015 17.3 29.9 0.0018 16.9 29.9 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PYC_OADA PF02436.18 KXH43342.1 - 0.16 11.7 2.1 0.21 11.3 1.6 1.5 1 1 0 1 1 1 0 Conserved carboxylase domain Rgp1 PF08737.10 KXH43342.1 - 5.3 6.1 6.2 6.7 5.8 6.2 1.2 1 0 0 1 1 1 0 Rgp1 Drc1-Sld2 PF11719.8 KXH43342.1 - 7.7 5.9 25.4 14 5.1 25.5 1.4 1 1 0 1 1 1 0 DNA replication and checkpoint protein TrmE_N PF10396.9 KXH43343.1 - 1.3e-35 122.2 0.0 2.7e-35 121.2 0.0 1.6 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus MnmE_helical PF12631.7 KXH43343.1 - 2.6e-31 109.4 0.2 3.5e-31 109.0 0.2 1.2 1 0 0 1 1 1 1 MnmE helical domain MMR_HSR1 PF01926.23 KXH43343.1 - 2.4e-17 63.1 0.0 4.1e-17 62.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KXH43343.1 - 5e-05 22.9 0.0 0.00013 21.6 0.0 1.6 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KXH43343.1 - 0.00097 19.2 0.2 0.0023 18.0 0.0 1.7 2 0 0 2 2 2 1 Dynamin family RsgA_GTPase PF03193.16 KXH43343.1 - 0.019 14.9 0.0 0.23 11.3 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_24 PF13479.6 KXH43343.1 - 0.036 13.8 0.0 0.069 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain NOA36 PF06524.12 KXH43344.1 - 0.5 9.7 4.3 0.56 9.5 4.3 1.1 1 0 0 1 1 1 0 NOA36 protein F-box-like PF12937.7 KXH43345.1 - 0.06 13.2 1.5 0.2 11.6 0.4 2.5 2 1 0 2 2 2 0 F-box-like Glyco_hydro_63 PF03200.16 KXH43346.1 - 4.6e-171 569.9 0.3 6.4e-170 566.1 0.3 2.2 1 1 0 1 1 1 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 KXH43346.1 - 3.8e-80 269.2 1.0 8.1e-80 268.2 0.2 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 63 N-terminal domain Trehalase PF01204.18 KXH43346.1 - 1.2e-08 34.3 0.0 2.3e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Trehalase TRAPPC9-Trs120 PF08626.11 KXH43348.1 - 0 1374.8 0.0 0 1374.5 0.0 1.1 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit Edc3_linker PF16598.5 KXH43348.1 - 0.058 14.1 2.3 0.16 12.7 2.3 1.7 1 0 0 1 1 1 0 Linker region of enhancer of mRNA-decapping protein 3 Chorismate_bind PF00425.18 KXH43349.1 - 6.4e-67 225.8 0.0 1.1e-65 221.7 0.0 2.3 1 1 0 1 1 1 1 chorismate binding enzyme GATase PF00117.28 KXH43349.1 - 5.4e-26 91.5 0.0 4.3e-25 88.6 0.0 2.1 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.13 KXH43349.1 - 4.9e-13 49.5 0.0 2.7e-12 47.1 0.0 2.1 2 0 0 2 2 2 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.13 KXH43349.1 - 7.2e-05 22.6 1.0 0.00068 19.4 1.0 2.1 1 1 0 1 1 1 1 Peptidase C26 Vps55 PF04133.14 KXH43350.1 - 2.3e-46 156.5 6.2 2.6e-46 156.3 6.2 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 Proteasome PF00227.26 KXH43351.1 - 2.8e-49 167.2 0.2 3.5e-49 166.9 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KXH43351.1 - 4.8e-11 42.1 0.2 7.8e-11 41.4 0.2 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Lysine_decarbox PF03641.14 KXH43352.1 - 3.8e-30 104.7 0.0 5.7e-30 104.1 0.0 1.3 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 KXH43352.1 - 1.3e-06 28.1 0.9 6.4e-06 25.8 0.9 2.1 1 1 0 1 1 1 1 SLOG cluster4 family DAGK_cat PF00781.24 KXH43352.1 - 0.18 11.4 1.7 2.9 7.5 0.1 2.7 3 0 0 3 3 3 0 Diacylglycerol kinase catalytic domain CLPTM1 PF05602.12 KXH43353.1 - 1.6e-152 508.4 0.0 2e-152 508.2 0.0 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) DUF1772 PF08592.11 KXH43353.1 - 0.3 11.4 2.1 1.8 8.8 0.5 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) Longin PF13774.6 KXH43355.1 - 1.1e-19 70.3 0.4 1.2e-18 66.9 0.4 2.3 1 1 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 KXH43355.1 - 2e-15 56.3 4.4 1.3e-14 53.8 0.0 2.2 2 0 0 2 2 2 1 Synaptobrevin SR-25 PF10500.9 KXH43355.1 - 0.02 14.5 14.7 0.035 13.7 14.7 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Ferlin_C PF16165.5 KXH43355.1 - 0.029 14.3 3.8 0.066 13.2 3.8 1.6 1 0 0 1 1 1 0 Ferlin C-terminus AP3D1 PF06375.11 KXH43355.1 - 0.036 14.3 12.4 0.071 13.3 12.4 1.4 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 Med19 PF10278.9 KXH43355.1 - 0.037 14.0 13.1 0.058 13.3 13.1 1.2 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 DUF4449 PF14613.6 KXH43355.1 - 0.045 13.9 9.6 0.031 14.4 6.8 1.9 2 1 1 3 3 3 0 Protein of unknown function (DUF4449) Sec62 PF03839.16 KXH43355.1 - 0.082 12.4 5.3 0.15 11.6 5.3 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 Flu_NS2 PF00601.19 KXH43355.1 - 0.091 13.1 2.2 0.11 12.8 1.0 1.7 2 0 0 2 2 2 0 Influenza non-structural protein (NS2) OAD_gamma PF04277.13 KXH43355.1 - 0.16 12.6 2.0 0.37 11.4 2.0 1.6 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Peptidase_S49_N PF08496.10 KXH43355.1 - 0.34 11.0 12.4 0.27 11.3 9.4 2.0 2 0 0 2 2 2 0 Peptidase family S49 N-terminal PIN_12 PF16289.5 KXH43355.1 - 0.54 10.7 9.4 0.41 11.1 7.3 1.7 2 0 0 2 2 2 0 PIN domain DUF4404 PF14357.6 KXH43355.1 - 0.94 10.2 5.7 7.5 7.3 0.9 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4404) DUF3987 PF13148.6 KXH43355.1 - 1.2 8.1 3.7 2.2 7.2 3.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) GST_C PF00043.25 KXH43355.1 - 2.6 8.3 4.6 51 4.2 4.6 2.4 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF4604 PF15377.6 KXH43355.1 - 3.4 8.1 17.0 5.8 7.3 17.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) ASXH PF13919.6 KXH43356.1 - 1.3e-39 135.4 0.2 2.8e-39 134.3 0.2 1.5 1 0 0 1 1 1 1 Asx homology domain Elong_Iki1 PF10483.9 KXH43357.1 - 1.5e-107 359.6 0.0 1.7e-107 359.4 0.0 1.0 1 0 0 1 1 1 1 Elongator subunit Iki1 NACHT PF05729.12 KXH43357.1 - 0.32 10.9 1.6 1.8 8.4 0.1 2.1 1 1 1 2 2 2 0 NACHT domain SNRNP27 PF08648.12 KXH43358.1 - 4.3e-28 97.2 1.5 7.9e-28 96.3 1.5 1.5 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins adh_short PF00106.25 KXH43359.1 - 6.4e-21 74.7 0.0 1e-20 74.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXH43359.1 - 1.2e-16 61.0 0.0 1.9e-16 60.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 KXH43359.1 - 0.18 11.1 0.0 0.27 10.6 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Aminotran_5 PF00266.19 KXH43360.1 - 9.8e-35 120.2 0.0 9.4e-24 84.0 0.0 2.0 1 1 1 2 2 2 2 Aminotransferase class-V Fungal_trans PF04082.18 KXH43361.1 - 7.3e-18 64.5 0.0 1.2e-17 63.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Aldedh PF00171.22 KXH43362.1 - 7.6e-108 361.0 0.0 9.2e-108 360.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Pro_dh PF01619.18 KXH43363.1 - 2e-61 208.1 0.0 2.4e-61 207.9 0.0 1.1 1 0 0 1 1 1 1 Proline dehydrogenase DUF410 PF04190.13 KXH43364.1 - 3.4e-93 312.1 0.0 4e-93 311.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF410) Transglut_core PF01841.19 KXH43365.1 - 1.9e-10 41.2 0.3 5.6e-10 39.7 0.3 1.8 1 0 0 1 1 1 1 Transglutaminase-like superfamily SH3_2 PF07653.17 KXH43365.1 - 7.8e-09 35.1 0.3 1.7e-08 34.0 0.3 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KXH43365.1 - 9.6e-05 21.9 2.3 0.00011 21.7 0.2 2.2 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 KXH43365.1 - 0.017 14.9 0.3 0.035 14.0 0.3 1.6 1 0 0 1 1 1 0 Variant SH3 domain Pkinase PF00069.25 KXH43366.1 - 5e-69 232.6 0.0 7.1e-69 232.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXH43366.1 - 2.1e-48 164.9 0.0 3.4e-48 164.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXH43366.1 - 4.6e-06 26.2 0.0 6.8e-05 22.3 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KXH43366.1 - 1.6e-05 23.9 0.0 3.8e-05 22.6 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 KXH43366.1 - 0.032 13.2 0.0 0.076 12.0 0.0 1.5 1 1 0 1 1 1 0 Haspin like kinase domain RAI1 PF08652.11 KXH43367.1 - 6.6e-29 99.9 0.0 2.3e-28 98.2 0.0 2.0 2 0 0 2 2 2 1 RAI1 like PD-(D/E)XK nuclease CEP76-C2 PF15627.6 KXH43367.1 - 0.17 11.4 0.0 0.64 9.6 0.0 1.8 2 0 0 2 2 2 0 CEP76 C2 domain Sec8_exocyst PF04048.14 KXH43368.1 - 6.1e-48 162.3 0.2 3.2e-47 160.0 0.2 2.2 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain Vps54_N PF10475.9 KXH43368.1 - 7.9e-09 35.2 0.5 1.5e-08 34.3 0.5 1.4 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex WD40 PF00400.32 KXH43369.1 - 1.3e-11 44.8 0.4 1.3e-08 35.3 0.1 2.9 3 0 0 3 3 3 2 WD domain, G-beta repeat Ge1_WD40 PF16529.5 KXH43369.1 - 0.15 11.0 0.0 0.19 10.7 0.0 1.1 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein p450 PF00067.22 KXH43370.1 - 1.3e-60 205.5 0.0 2e-60 204.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 P22_Tail-4 PF11650.8 KXH43370.1 - 0.15 12.0 0.0 0.27 11.2 0.0 1.3 1 0 0 1 1 1 0 P22 tail accessory factor Aminotran_1_2 PF00155.21 KXH43371.1 - 6.5e-16 58.5 0.0 9e-16 58.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 KXH43371.1 - 2.6e-07 29.8 0.0 9.6e-07 27.9 0.0 1.7 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase DegT_DnrJ_EryC1 PF01041.17 KXH43371.1 - 0.00093 18.6 0.1 0.026 13.8 0.0 2.1 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Glyco_hydro_16 PF00722.21 KXH43372.1 - 9.6e-45 152.2 1.3 1.4e-44 151.6 1.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Topoisom_I PF01028.20 KXH43373.1 - 2.2e-97 324.8 8.3 4.3e-97 323.9 8.3 1.5 1 0 0 1 1 1 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.15 KXH43373.1 - 1.3e-96 322.2 5.7 1.3e-96 322.2 5.7 2.9 4 0 0 4 4 4 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topo_C_assoc PF14370.6 KXH43373.1 - 4.3e-31 106.6 0.6 4.3e-31 106.6 0.6 2.5 2 0 0 2 2 2 1 C-terminal topoisomerase domain VasI PF11319.8 KXH43373.1 - 0.016 14.9 0.1 0.016 14.9 0.1 2.3 2 0 0 2 2 2 0 Type VI secretion system VasI, EvfG, VC_A0118 PspB PF06667.12 KXH43373.1 - 0.066 13.3 0.1 0.26 11.4 0.1 2.0 1 0 0 1 1 1 0 Phage shock protein B BLOC1_2 PF10046.9 KXH43373.1 - 6.7 7.1 7.5 38 4.7 0.9 3.3 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ATP-synt PF00231.19 KXH43374.1 - 5.2e-79 265.9 2.7 6.3e-79 265.6 2.7 1.0 1 0 0 1 1 1 1 ATP synthase DUF5471 PF17565.2 KXH43374.1 - 0.026 14.8 0.2 0.086 13.1 0.2 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF5471) Sec1 PF00995.23 KXH43375.1 - 1.8e-127 427.0 0.0 2.3e-127 426.7 0.0 1.1 1 0 0 1 1 1 1 Sec1 family Amino_oxidase PF01593.24 KXH43375.1 - 3.3e-80 270.6 0.1 2.8e-68 231.3 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase SWIRM PF04433.17 KXH43375.1 - 7.1e-15 55.1 0.0 2.6e-14 53.3 0.0 2.0 1 0 0 1 1 1 1 SWIRM domain NAD_binding_8 PF13450.6 KXH43375.1 - 1.1e-06 28.7 0.0 4.2e-06 26.9 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HMG_box PF00505.19 KXH43375.1 - 2.1e-06 28.1 4.3 9.1e-06 26.0 4.3 2.1 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KXH43375.1 - 0.00025 21.6 4.1 0.00056 20.4 4.1 1.6 1 0 0 1 1 1 1 HMG-box domain Pyr_redox_2 PF07992.14 KXH43375.1 - 0.0048 16.2 0.0 0.13 11.5 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXH43375.1 - 0.014 15.0 0.5 0.035 13.7 0.5 1.7 1 0 0 1 1 1 0 FAD dependent oxidoreductase UQ_con PF00179.26 KXH43376.1 - 4.8e-28 97.6 0.0 5.6e-28 97.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KXH43376.1 - 1.6e-06 27.8 0.0 4e-06 26.6 0.0 1.5 1 1 1 2 2 2 1 Prokaryotic E2 family B RWD PF05773.22 KXH43376.1 - 0.0006 20.1 0.1 0.00071 19.8 0.1 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.13 KXH43376.1 - 0.0028 17.5 0.1 0.0037 17.1 0.1 1.2 1 0 0 1 1 1 1 UEV domain Pkinase PF00069.25 KXH43377.1 - 1.8e-62 211.1 0.1 1.9e-31 109.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXH43377.1 - 1.6e-27 96.4 0.5 7.3e-27 94.3 0.0 2.2 2 1 0 2 2 2 1 Protein tyrosine kinase tRNA-synt_His PF13393.6 KXH43380.1 - 1.7e-39 135.9 0.0 3.8e-33 115.1 0.0 2.2 2 0 0 2 2 2 2 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 KXH43380.1 - 1.8e-11 44.1 0.0 3.2e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 KXH43380.1 - 0.0001 22.3 0.0 0.00031 20.8 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon2 PF12745.7 KXH43380.1 - 0.0017 17.9 0.1 0.018 14.6 0.0 2.2 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs Ribosomal_60s PF00428.19 KXH43380.1 - 3.5 8.3 17.2 21 5.8 0.0 2.7 3 0 0 3 3 3 0 60s Acidic ribosomal protein ABC_membrane PF00664.23 KXH43381.1 - 4.8e-88 295.4 34.7 7.9e-51 173.3 10.3 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KXH43381.1 - 1e-65 220.4 0.2 7.6e-33 113.9 0.1 3.4 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KXH43381.1 - 9.2e-17 61.2 3.8 8.2e-09 35.2 0.2 3.5 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KXH43381.1 - 4.5e-09 36.4 0.2 3.1e-05 23.9 0.1 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 KXH43381.1 - 6.5e-08 33.1 0.2 0.01 16.2 0.0 3.4 3 0 0 3 3 3 2 AAA ATPase domain AAA_15 PF13175.6 KXH43381.1 - 2.4e-07 30.8 1.1 0.0066 16.2 0.2 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 KXH43381.1 - 1.5e-06 27.9 1.9 0.0011 18.7 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 KXH43381.1 - 1.7e-06 28.3 0.9 0.1 12.9 0.0 3.1 3 1 0 3 3 2 2 AAA domain ABC_ATPase PF09818.9 KXH43381.1 - 2.1e-06 26.8 0.4 0.17 10.6 0.0 3.6 3 1 0 3 3 3 2 Predicted ATPase of the ABC class AAA_30 PF13604.6 KXH43381.1 - 4.9e-05 23.1 1.8 0.11 12.2 0.1 3.0 3 0 0 3 3 3 2 AAA domain ATP-synt_ab PF00006.25 KXH43381.1 - 6.5e-05 22.7 0.1 0.33 10.6 0.0 2.6 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain AAA_25 PF13481.6 KXH43381.1 - 0.00013 21.6 0.6 1 8.9 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA PF00004.29 KXH43381.1 - 0.00022 21.6 1.6 17 5.9 0.0 4.5 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) AAA_21 PF13304.6 KXH43381.1 - 0.00038 20.4 0.1 0.62 9.8 0.0 2.8 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system DUF3987 PF13148.6 KXH43381.1 - 0.00094 18.3 0.2 0.0019 17.3 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3987) AAA_7 PF12775.7 KXH43381.1 - 0.0011 18.5 0.1 1.4 8.4 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_5 PF07728.14 KXH43381.1 - 0.0012 18.8 0.4 2 8.4 0.0 3.1 4 0 0 4 4 2 2 AAA domain (dynein-related subfamily) PRK PF00485.18 KXH43381.1 - 0.0013 18.5 0.1 0.94 9.2 0.0 2.4 2 0 0 2 2 2 2 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.6 KXH43381.1 - 0.0066 16.6 1.0 0.17 12.0 0.0 2.7 3 0 0 3 3 2 1 AAA domain Rad17 PF03215.15 KXH43381.1 - 0.011 15.7 0.1 2 8.3 0.1 2.6 2 0 0 2 2 2 0 Rad17 P-loop domain SbcCD_C PF13558.6 KXH43381.1 - 0.015 15.5 2.2 3.2 8.1 0.3 3.9 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.6 KXH43381.1 - 0.016 15.8 0.1 1.8 9.1 0.1 2.6 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 KXH43381.1 - 0.017 15.6 0.1 0.017 15.6 0.1 3.3 2 1 1 3 3 2 0 AAA domain AAA_14 PF13173.6 KXH43381.1 - 0.017 15.1 1.6 1.5 8.9 0.2 3.0 3 0 0 3 3 2 0 AAA domain NB-ARC PF00931.22 KXH43381.1 - 0.024 13.8 0.2 3.6 6.7 0.0 2.9 3 0 0 3 3 3 0 NB-ARC domain AAA_24 PF13479.6 KXH43381.1 - 0.026 14.2 0.5 8.3 6.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KXH43381.1 - 0.034 13.4 1.2 7.6 5.8 0.1 2.8 3 0 0 3 3 2 0 Zeta toxin RNA_helicase PF00910.22 KXH43381.1 - 0.095 13.1 0.2 31 5.0 0.1 2.8 2 0 0 2 2 2 0 RNA helicase Roc PF08477.13 KXH43381.1 - 0.13 12.5 1.9 22 5.3 1.2 2.8 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_28 PF13521.6 KXH43381.1 - 0.14 12.4 0.1 14 5.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 KXH43381.1 - 0.15 11.8 0.1 1.9 8.2 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DUF4710 PF15828.5 KXH43381.1 - 0.31 11.2 4.2 0.79 9.9 4.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4710) AP3D1 PF06375.11 KXH43381.1 - 0.43 10.8 8.4 0.18 12.0 4.8 2.0 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 Cupin_2 PF07883.11 KXH43382.1 - 3.6e-08 33.0 0.1 8.5e-08 31.8 0.0 1.7 2 0 0 2 2 2 1 Cupin domain Cupin_1 PF00190.22 KXH43382.1 - 0.00039 20.1 0.0 0.00057 19.5 0.0 1.3 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.12 KXH43382.1 - 0.0027 17.4 0.1 0.0045 16.6 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF861) FAD_binding_3 PF01494.19 KXH43383.1 - 7.8e-22 78.0 0.0 1.2e-21 77.4 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain ADC PF06314.11 KXH43383.1 - 8.9e-17 61.4 0.0 1.6e-16 60.6 0.0 1.4 1 0 0 1 1 1 1 Acetoacetate decarboxylase (ADC) NAD_binding_8 PF13450.6 KXH43383.1 - 5.6e-07 29.7 1.1 9.7e-07 28.9 0.1 1.9 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXH43383.1 - 3.7e-06 26.4 0.8 1.6e-05 24.3 0.8 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXH43383.1 - 2.1e-05 24.3 2.1 3.3e-05 23.6 1.9 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KXH43383.1 - 0.0026 16.9 0.8 0.0052 15.9 0.8 1.5 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 KXH43383.1 - 0.017 14.2 0.1 0.026 13.6 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A HI0933_like PF03486.14 KXH43383.1 - 0.041 12.6 0.1 0.066 11.9 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein 3HCDH_N PF02737.18 KXH43383.1 - 0.05 13.5 0.1 0.087 12.7 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.27 KXH43383.1 - 0.075 13.6 0.1 0.24 12.0 0.1 1.9 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KXH43383.1 - 0.097 12.0 0.2 0.19 11.1 0.2 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase ApbA PF02558.16 KXH43383.1 - 0.16 11.6 0.3 0.29 10.7 0.3 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Trp_halogenase PF04820.14 KXH43383.1 - 0.21 10.4 0.5 0.76 8.6 0.1 1.9 1 1 1 2 2 2 0 Tryptophan halogenase NAD_binding_9 PF13454.6 KXH43383.1 - 0.26 11.3 1.1 0.92 9.5 1.1 1.9 1 1 0 1 1 1 0 FAD-NAD(P)-binding adh_short PF00106.25 KXH43384.1 - 1.7e-27 96.1 0.1 3.9e-26 91.7 0.1 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXH43384.1 - 4.2e-20 72.3 0.6 7.6e-19 68.2 0.6 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH43384.1 - 7.1e-07 29.3 0.2 1.1e-06 28.7 0.2 1.3 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KXH43384.1 - 0.005 16.7 0.3 0.0073 16.2 0.3 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SPOR PF05036.13 KXH43384.1 - 0.048 14.0 0.3 0.87 10.0 0.2 2.2 1 1 1 2 2 2 0 Sporulation related domain F420_oxidored PF03807.17 KXH43384.1 - 0.05 14.2 0.2 0.075 13.6 0.2 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent MFS_1 PF07690.16 KXH43385.1 - 2e-35 122.4 38.1 7.8e-35 120.4 32.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH43385.1 - 4.5e-14 52.2 13.9 4.5e-14 52.2 13.9 3.0 2 2 0 3 3 3 1 Sugar (and other) transporter Fzo_mitofusin PF04799.13 KXH43385.1 - 0.074 12.6 0.2 0.13 11.8 0.2 1.3 1 0 0 1 1 1 0 fzo-like conserved region Fungal_trans PF04082.18 KXH43386.1 - 4.7e-14 52.1 0.3 9.4e-14 51.1 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KXH43386.1 - 4.5e-10 39.4 12.7 0.00014 22.1 0.2 3.6 3 0 0 3 3 3 2 Zinc finger, C2H2 type Zn_clus PF00172.18 KXH43386.1 - 7.8e-07 29.1 11.0 7.8e-07 29.1 11.0 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_4 PF13894.6 KXH43386.1 - 9.4e-06 26.1 15.4 0.0041 17.8 0.1 3.6 3 0 0 3 3 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KXH43386.1 - 0.0016 18.7 0.3 0.0016 18.7 0.3 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_11 PF16622.5 KXH43386.1 - 0.012 15.3 6.3 1.9 8.3 2.7 3.0 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-met PF12874.7 KXH43386.1 - 0.019 15.4 2.5 4 8.0 0.8 3.2 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-MYST PF17772.1 KXH43386.1 - 0.029 14.0 0.9 1.2 8.8 0.1 3.0 3 0 0 3 3 3 0 MYST family zinc finger domain zf-C2H2_jaz PF12171.8 KXH43386.1 - 0.19 12.1 9.5 0.62 10.4 0.1 3.4 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 KXH43386.1 - 0.46 10.8 3.6 2.2 8.6 3.5 2.1 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 KXH43386.1 - 0.77 9.8 3.4 0.24 11.5 0.1 1.9 2 0 0 2 2 2 0 C2H2-type zinc finger Hydrolase_4 PF12146.8 KXH43387.1 - 1.7e-13 50.4 0.1 5.6e-13 48.7 0.1 1.8 2 1 1 3 3 3 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KXH43387.1 - 4.3e-13 50.4 2.7 7.2e-13 49.6 2.7 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXH43387.1 - 5.9e-12 45.8 0.0 8.7e-12 45.2 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 KXH43387.1 - 0.0037 17.0 0.0 0.011 15.5 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family UPF0227 PF05728.12 KXH43387.1 - 0.014 15.4 0.0 0.37 10.7 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) Ndr PF03096.14 KXH43387.1 - 0.11 11.2 0.1 0.32 9.6 0.0 1.6 1 1 0 1 1 1 0 Ndr family Beta_elim_lyase PF01212.21 KXH43387.1 - 0.14 11.4 0.0 0.2 10.9 0.0 1.1 1 0 0 1 1 1 0 Beta-eliminating lyase Lipase_3 PF01764.25 KXH43387.1 - 0.17 11.8 0.0 0.31 10.9 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) FYVE PF01363.21 KXH43388.1 - 1.8e-20 72.9 0.7 1.8e-20 72.9 0.7 2.9 3 0 0 3 3 3 1 FYVE zinc finger zf-RING_2 PF13639.6 KXH43388.1 - 4.5e-07 30.1 5.2 4.5e-07 30.1 5.2 3.9 4 0 0 4 4 4 1 Ring finger domain zf-C3HC4_2 PF13923.6 KXH43388.1 - 0.00023 20.9 3.9 0.00023 20.9 3.9 3.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KXH43388.1 - 0.00034 20.3 4.7 0.00034 20.3 4.7 2.5 3 0 0 3 3 3 1 RING-like zinc finger zf-RING_UBOX PF13445.6 KXH43388.1 - 0.006 16.6 5.5 0.006 16.6 5.5 3.6 3 0 0 3 3 3 1 RING-type zinc-finger Rad50_zn_hook PF04423.14 KXH43388.1 - 0.02 14.7 0.4 0.02 14.7 0.4 1.8 2 0 0 2 2 1 0 Rad50 zinc hook motif zf-C3HC4 PF00097.25 KXH43388.1 - 0.022 14.7 3.6 0.022 14.7 3.6 3.5 4 0 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) zf-piccolo PF05715.13 KXH43388.1 - 0.5 10.6 16.9 0.22 11.7 5.9 3.0 3 0 0 3 3 3 0 Piccolo Zn-finger FYVE_2 PF02318.16 KXH43388.1 - 1.2 9.3 9.4 0.72 10.1 2.1 2.5 2 0 0 2 2 2 0 FYVE-type zinc finger DZR PF12773.7 KXH43388.1 - 1.8 8.6 7.4 34 4.6 3.7 2.9 2 0 0 2 2 2 0 Double zinc ribbon Elf1 PF05129.13 KXH43388.1 - 4.1 7.5 13.1 0.68 10.0 2.5 3.4 4 0 0 4 4 4 0 Transcription elongation factor Elf1 like HeLo PF14479.6 KXH43456.1 - 3.6e-15 56.3 0.5 7.7e-15 55.3 0.5 1.6 1 1 0 1 1 1 1 Prion-inhibition and propagation ZapB PF06005.12 KXH43456.1 - 0.35 11.3 3.1 0.2 12.1 0.4 1.9 2 0 0 2 2 2 0 Cell division protein ZapB TPR_12 PF13424.6 KXH43457.1 - 2.7e-26 91.6 65.0 6.8e-05 23.1 3.9 12.7 10 1 6 16 16 15 10 Tetratricopeptide repeat Pkinase PF00069.25 KXH43457.1 - 1e-24 87.3 0.0 2.2e-24 86.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Ank_2 PF12796.7 KXH43457.1 - 6.8e-20 71.4 0.0 0.0014 19.2 0.0 7.4 3 2 3 6 6 6 3 Ankyrin repeats (3 copies) Pkinase_Tyr PF07714.17 KXH43457.1 - 3.7e-19 69.0 0.0 8.5e-19 67.8 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_3 PF13606.6 KXH43457.1 - 3.2e-13 48.6 9.8 0.55 11.0 0.0 11.2 12 0 0 12 12 10 2 Ankyrin repeat TPR_10 PF13374.6 KXH43457.1 - 8e-11 41.5 46.0 0.014 15.3 2.2 14.1 15 0 0 15 15 15 4 Tetratricopeptide repeat Ank_4 PF13637.6 KXH43457.1 - 2.4e-09 37.5 1.6 0.057 14.0 0.2 6.4 4 2 1 6 6 5 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXH43457.1 - 1.3e-06 28.5 0.0 2.6 8.5 0.0 6.7 7 0 0 7 7 5 1 Ankyrin repeats (many copies) TPR_19 PF14559.6 KXH43457.1 - 1.7e-05 25.2 21.1 0.17 12.4 0.1 9.6 8 2 2 10 10 10 1 Tetratricopeptide repeat TPR_2 PF07719.17 KXH43457.1 - 5e-05 23.1 34.4 1 9.6 0.4 10.4 12 0 0 12 12 9 3 Tetratricopeptide repeat PPR PF01535.20 KXH43457.1 - 0.00069 19.7 0.2 57 4.3 0.0 5.7 6 0 0 6 6 4 0 PPR repeat TPR_8 PF13181.6 KXH43457.1 - 0.00083 19.4 20.9 3.1 8.2 0.1 9.7 10 0 0 10 10 10 1 Tetratricopeptide repeat Ank PF00023.30 KXH43457.1 - 0.00084 19.7 13.0 13 6.5 0.1 7.6 7 0 0 7 7 7 0 Ankyrin repeat TPR_14 PF13428.6 KXH43457.1 - 0.0022 18.6 33.3 0.42 11.6 0.1 11.2 11 1 1 12 12 9 1 Tetratricopeptide repeat DNA_pol3_tau_5 PF12170.8 KXH43457.1 - 0.014 15.5 0.8 0.11 12.6 0.8 2.6 1 0 0 1 1 1 0 DNA polymerase III tau subunit V interacting with alpha Kdo PF06293.14 KXH43457.1 - 0.016 14.6 0.0 0.04 13.3 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Sel1 PF08238.12 KXH43457.1 - 0.09 13.5 0.1 0.47 11.2 0.0 2.4 2 0 0 2 2 1 0 Sel1 repeat DUF4638 PF15472.6 KXH43457.1 - 0.094 12.4 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) TPR_7 PF13176.6 KXH43457.1 - 0.52 10.5 17.2 80 3.6 0.2 9.3 9 0 0 9 9 8 0 Tetratricopeptide repeat TPR_6 PF13174.6 KXH43457.1 - 1.1 10.0 8.2 36 5.3 0.0 6.2 6 0 0 6 6 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 KXH43457.1 - 2.8 8.7 22.4 3.2 8.5 0.6 7.9 10 0 0 10 10 7 0 Tetratricopeptide repeat Abhydrolase_6 PF12697.7 KXH43458.1 - 1.8e-12 48.4 0.2 2.2e-12 48.1 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXH43458.1 - 2.2e-09 37.3 0.0 3.4e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXH43458.1 - 0.003 16.9 0.0 0.007 15.7 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DUF1057 PF06342.12 KXH43458.1 - 0.12 11.4 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) Fungal_trans_2 PF11951.8 KXH43459.1 - 0.00011 21.2 0.2 0.00056 18.8 0.0 2.1 2 1 1 3 3 3 1 Fungal specific transcription factor domain PSII_Pbs31 PF18240.1 KXH43459.1 - 0.06 13.8 0.0 0.15 12.5 0.0 1.6 1 0 0 1 1 1 0 Photosystem II Psb31 protein 7tm_2 PF00002.24 KXH43460.1 - 8.3e-10 38.4 9.2 8.3e-10 38.4 9.2 1.6 2 0 0 2 2 2 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.11 KXH43460.1 - 2.8e-07 30.0 9.4 2.8e-07 30.0 9.4 2.0 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor Git3 PF11710.8 KXH43460.1 - 1.7e-06 28.0 10.7 2.9e-06 27.2 10.7 1.3 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.21 KXH43460.1 - 7.9e-06 25.4 3.7 1.1e-05 25.0 3.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF2905 PF11146.8 KXH43460.1 - 0.17 12.1 1.3 0.35 11.1 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2905) Ocular_alb PF02101.15 KXH43460.1 - 0.23 10.4 6.6 0.39 9.6 6.6 1.4 1 0 0 1 1 1 0 Ocular albinism type 1 protein CTP_transf_like PF01467.26 KXH43462.1 - 2.5e-22 79.6 0.0 3.1e-22 79.3 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase-like p450 PF00067.22 KXH43463.1 - 9.2e-70 235.7 0.0 1e-69 235.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 YlbE PF14003.6 KXH43463.1 - 0.0078 16.6 0.3 0.016 15.6 0.3 1.4 1 0 0 1 1 1 1 YlbE-like protein Ring_hydroxyl_A PF00848.19 KXH43464.1 - 5.5e-25 88.6 6.1 1.7e-12 47.8 2.1 2.3 1 1 1 2 2 2 2 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.26 KXH43464.1 - 1.1e-16 60.5 0.0 1.9e-16 59.7 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain DUF924 PF06041.11 KXH43465.1 - 6.5e-53 179.5 0.4 7.7e-53 179.3 0.4 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF924) FBPase PF00316.20 KXH43466.1 - 1.1e-22 80.5 0.0 1.9e-22 79.7 0.0 1.3 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain MFS_1 PF07690.16 KXH43467.1 - 2.5e-32 112.2 35.0 3e-31 108.6 30.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Spectrin_like PF18373.1 KXH43467.1 - 0.12 12.5 0.2 0.75 9.9 0.2 2.1 2 0 0 2 2 2 0 Spectrin like domain Bac_luciferase PF00296.20 KXH43468.1 - 1.3e-56 192.3 0.2 2e-56 191.7 0.2 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase Glyco_hydro_3 PF00933.21 KXH43469.1 - 3.5e-50 171.2 0.0 4.9e-50 170.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 KXH43469.1 - 6.4e-14 52.4 0.2 2.6e-12 47.1 0.0 2.1 1 1 1 2 2 2 2 Glycosyl hydrolase family 3 C-terminal domain Mannosyl_trans3 PF11051.8 KXH43470.1 - 1.7e-44 152.2 0.0 3.1e-44 151.4 0.0 1.4 1 1 0 1 1 1 1 Mannosyltransferase putative Nucleotid_trans PF03407.16 KXH43470.1 - 0.069 13.1 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase DUF948 PF06103.11 KXH43471.1 - 0.00061 20.0 1.8 0.00061 20.0 1.8 3.0 3 0 0 3 3 3 1 Bacterial protein of unknown function (DUF948) Atg14 PF10186.9 KXH43471.1 - 0.074 12.1 16.7 0.11 11.6 16.7 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 FUSC PF04632.12 KXH43471.1 - 0.076 11.5 1.3 0.1 11.1 1.3 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Diphtheria_T PF02764.14 KXH43471.1 - 0.092 12.8 1.7 0.15 12.1 1.7 1.4 1 0 0 1 1 1 0 Diphtheria toxin, T domain DUF390 PF04094.14 KXH43471.1 - 0.098 10.9 6.9 0.12 10.6 6.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF390) Pox_A_type_inc PF04508.12 KXH43471.1 - 0.15 12.0 0.1 0.15 12.0 0.1 3.5 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat GldM_N PF12081.8 KXH43471.1 - 0.17 12.0 16.0 0.19 11.8 12.4 2.3 1 1 0 2 2 2 0 GldM N-terminal domain DUF4145 PF13643.6 KXH43471.1 - 0.37 10.9 8.0 0.29 11.3 4.2 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4145) DUF5344 PF17279.2 KXH43471.1 - 1.3 9.6 18.9 0.1 13.2 7.3 3.4 2 2 1 3 3 3 0 Family of unknown function (DUF5344) bZIP_1 PF00170.21 KXH43471.1 - 4.3 7.5 16.4 0.13 12.4 3.8 3.5 3 1 0 3 3 3 0 bZIP transcription factor BEX PF04538.12 KXH43472.1 - 0.01 16.5 3.8 0.01 16.5 3.8 1.7 1 1 1 2 2 2 0 Brain expressed X-linked like family KxDL PF10241.9 KXH43472.1 - 0.035 14.4 0.7 0.074 13.3 0.7 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein DUF4795 PF16043.5 KXH43472.1 - 0.049 13.2 4.4 0.07 12.7 4.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) THOC7 PF05615.13 KXH43472.1 - 0.055 13.7 4.4 0.08 13.2 4.4 1.2 1 0 0 1 1 1 0 Tho complex subunit 7 DUF4600 PF15372.6 KXH43472.1 - 0.057 13.8 4.5 0.076 13.4 4.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4600) Atg14 PF10186.9 KXH43472.1 - 0.064 12.3 1.6 0.07 12.2 1.6 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 UPF0242 PF06785.11 KXH43472.1 - 0.076 13.1 2.8 0.097 12.8 2.8 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus BST2 PF16716.5 KXH43472.1 - 0.11 13.1 2.8 0.29 11.7 2.7 1.8 1 1 0 1 1 1 0 Bone marrow stromal antigen 2 GrpE PF01025.19 KXH43472.1 - 0.25 11.0 8.9 0.064 12.9 4.9 1.8 1 1 1 2 2 2 0 GrpE PEARLI-4 PF05278.12 KXH43472.1 - 1.8 8.1 10.5 2.5 7.6 10.5 1.1 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) Transket_pyr PF02779.24 KXH43485.1 - 4e-62 209.1 0.0 7.1e-62 208.2 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 KXH43485.1 - 1.3e-56 191.8 0.0 1.8e-56 191.3 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 KXH43485.1 - 3.1e-55 186.1 0.0 5.3e-55 185.3 0.0 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 KXH43485.1 - 6.8e-20 70.4 1.3 1.5e-19 69.3 1.3 1.6 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus YceG_bac PF14266.6 KXH43485.1 - 0.18 10.7 0.1 0.29 10.0 0.1 1.2 1 0 0 1 1 1 0 Putative component of 'biosynthetic module' baeRF_family12 PF18856.1 KXH43485.1 - 0.19 12.3 0.4 0.56 10.8 0.0 1.9 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 12 BioY PF02632.14 KXH43485.1 - 0.21 11.6 0.2 0.36 10.9 0.2 1.2 1 0 0 1 1 1 0 BioY family RasGAP PF00616.19 KXH43486.1 - 9e-32 110.5 0.6 2.4e-18 66.6 0.0 3.0 2 1 1 3 3 3 2 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.6 KXH43486.1 - 2.4e-09 37.5 0.3 6.1e-09 36.1 0.3 1.6 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain XRN_M PF17846.1 KXH43487.1 - 1.2e-137 459.5 0.3 4.5e-137 457.6 0.0 2.0 2 1 0 2 2 2 1 Xrn1 helical domain XRN_N PF03159.18 KXH43487.1 - 4.6e-99 330.7 0.0 8.1e-99 329.9 0.0 1.4 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus zf-CCHC_2 PF13696.6 KXH43487.1 - 0.12 12.2 2.2 0.29 11.0 2.2 1.6 1 0 0 1 1 1 0 Zinc knuckle Uso1_p115_head PF04869.14 KXH43488.1 - 7.8e-119 396.4 0.0 2e-118 395.1 0.0 1.8 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.13 KXH43488.1 - 5.5e-08 33.2 16.4 5.5e-08 33.2 16.4 4.4 1 1 3 4 4 4 1 Uso1 / p115 like vesicle tethering protein, C terminal region Apolipoprotein PF01442.18 KXH43488.1 - 0.00052 19.9 43.2 0.00052 19.9 43.2 3.4 1 1 2 3 3 3 1 Apolipoprotein A1/A4/E domain Methyltransf_25 PF13649.6 KXH43489.1 - 8.9e-14 52.0 0.0 2.2e-13 50.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH43489.1 - 5.4e-12 46.2 0.0 1.7e-11 44.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KXH43489.1 - 1.3e-10 41.1 0.0 2.9e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 KXH43489.1 - 9.7e-09 35.2 0.0 2.2e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXH43489.1 - 3.5e-06 27.0 0.0 9.6e-06 25.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH43489.1 - 3.7e-06 27.6 0.0 1.2e-05 25.9 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 KXH43489.1 - 7.2e-06 26.0 0.0 1.2e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXH43489.1 - 1.4e-05 24.7 0.1 2.4e-05 24.0 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain RasGAP_C PF03836.15 KXH43489.1 - 0.0021 18.2 0.1 0.004 17.3 0.1 1.4 1 0 0 1 1 1 1 RasGAP C-terminus CMAS PF02353.20 KXH43489.1 - 0.0029 17.0 0.0 0.024 13.9 0.0 2.0 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_16 PF10294.9 KXH43489.1 - 0.0029 17.4 0.0 0.007 16.1 0.0 1.6 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_9 PF08003.11 KXH43489.1 - 0.0041 16.1 0.0 0.0071 15.3 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1698) TehB PF03848.14 KXH43489.1 - 0.027 13.9 0.1 0.044 13.2 0.1 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB UPF0020 PF01170.18 KXH43489.1 - 0.034 13.8 0.0 0.1 12.2 0.0 1.7 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 Ubie_methyltran PF01209.18 KXH43489.1 - 0.038 13.3 0.1 0.063 12.6 0.1 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family PCMT PF01135.19 KXH43489.1 - 0.11 12.3 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) OPT PF03169.15 KXH43490.1 - 5.8e-151 504.2 26.3 6.7e-151 504.0 26.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Phage_holin_2_3 PF16080.5 KXH43490.1 - 0.74 9.6 4.7 0.92 9.3 0.6 3.2 2 0 0 2 2 2 0 Bacteriophage holin family HP1 Rav1p_C PF12234.8 KXH43491.1 - 2.7e-257 855.3 0.6 8.7e-245 814.0 0.1 3.0 2 1 1 3 3 3 2 RAVE protein 1 C terminal DUF4968 PF16338.5 KXH43491.1 - 0.059 13.7 0.0 92 3.4 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4968) WD40 PF00400.32 KXH43491.1 - 2.9 8.9 12.4 7.4 7.6 0.1 5.1 8 0 0 8 8 8 0 WD domain, G-beta repeat Sfi1 PF08457.10 KXH43492.1 - 1.3e-32 113.2 46.7 2.4e-17 62.7 11.5 2.3 2 0 0 2 2 2 2 Sfi1 spindle body protein CX9C PF16860.5 KXH43493.1 - 0.00099 19.1 0.6 0.0013 18.7 0.6 1.1 1 0 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, tRNA-synt_1 PF00133.22 KXH43494.1 - 8.3e-221 734.4 0.0 1.7e-220 733.4 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KXH43494.1 - 1.7e-25 89.8 0.0 5.4e-25 88.1 0.0 1.8 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KXH43494.1 - 7.7e-15 54.5 0.0 1.5e-05 24.0 0.0 4.0 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 KXH43494.1 - 0.0073 15.7 0.0 0.043 13.2 0.0 2.2 3 0 0 3 3 3 1 tRNA synthetases class I (C) catalytic domain Mo25 PF08569.11 KXH43495.1 - 2.4e-130 434.7 0.1 2.7e-130 434.5 0.1 1.0 1 0 0 1 1 1 1 Mo25-like DNA_topoisoIV PF00521.20 KXH43495.1 - 0.0097 14.8 0.0 0.019 13.8 0.0 1.4 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A SWIB PF02201.18 KXH43496.1 - 5.4e-23 80.7 0.0 1.6e-22 79.1 0.0 1.8 2 0 0 2 2 2 1 SWIB/MDM2 domain EF-hand_1 PF00036.32 KXH43501.1 - 9e-27 90.6 13.2 2.4e-07 29.8 0.8 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KXH43501.1 - 2.3e-23 82.4 13.9 3.1e-14 53.2 1.4 2.7 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 KXH43501.1 - 1.5e-20 71.3 6.6 4.6e-05 23.0 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KXH43501.1 - 7.1e-18 63.2 11.0 1.7e-06 27.2 0.4 4.3 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 KXH43501.1 - 8.3e-13 48.0 12.6 0.00013 21.7 0.5 4.2 2 1 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KXH43501.1 - 6e-07 29.8 0.1 0.0014 18.9 0.1 2.3 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KXH43501.1 - 4.8e-06 26.5 8.2 0.0024 17.8 0.5 3.8 1 1 3 4 4 4 2 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 KXH43501.1 - 0.029 14.6 0.8 0.12 12.6 0.7 2.2 1 1 0 1 1 1 0 Dockerin type I domain EF-hand_9 PF14658.6 KXH43501.1 - 0.092 13.1 0.2 4.4 7.7 0.1 3.1 2 1 1 3 3 3 0 EF-hand domain EPL1 PF10513.9 KXH43502.1 - 5.3e-21 75.6 3.0 5.3e-21 75.6 3.0 2.8 2 1 0 2 2 2 1 Enhancer of polycomb-like Peptidase_M22 PF00814.25 KXH43503.1 - 5.9e-84 282.0 0.0 7.4e-84 281.7 0.0 1.1 1 0 0 1 1 1 1 Glycoprotease family Carbam_trans_N PF02543.15 KXH43503.1 - 0.12 12.0 0.0 1 9.0 0.0 2.0 2 0 0 2 2 2 0 Carbamoyltransferase N-terminus AMPK1_CBM PF16561.5 KXH43504.1 - 3.3e-25 88.1 0.0 5.9e-25 87.3 0.0 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase AMPKBI PF04739.15 KXH43504.1 - 9.2e-25 86.7 1.9 9.2e-25 86.7 1.9 2.4 2 0 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interaction domain UPF0542 PF15086.6 KXH43505.1 - 0.045 13.7 1.4 0.078 12.9 1.4 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 Pkinase PF00069.25 KXH43506.1 - 1.3e-61 208.3 0.0 2.2e-61 207.6 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXH43506.1 - 6.8e-29 100.9 0.0 4e-28 98.4 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXH43506.1 - 0.0051 16.2 0.1 0.017 14.4 0.1 1.9 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KXH43506.1 - 0.014 14.2 0.0 0.022 13.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 KXH43506.1 - 0.027 13.4 0.3 0.16 10.9 0.3 1.8 1 1 0 1 1 1 0 Haspin like kinase domain Asparaginase PF00710.20 KXH43507.1 - 3e-57 193.3 0.0 7.8e-57 191.9 0.0 1.7 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 KXH43507.1 - 1e-25 90.2 0.0 1.9e-25 89.3 0.0 1.5 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain Ank_2 PF12796.7 KXH43507.1 - 7.7e-09 36.0 0.9 0.00023 21.7 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXH43507.1 - 1.3e-05 25.7 0.0 0.0024 18.4 0.0 2.6 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 KXH43507.1 - 4.3e-05 23.8 0.1 2.1 8.9 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 KXH43507.1 - 0.00099 19.4 0.4 0.023 15.0 0.4 2.6 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXH43507.1 - 0.037 14.6 0.0 32 5.5 0.0 3.7 3 0 0 3 3 3 0 Ankyrin repeat Rhomboid PF01694.22 KXH43510.1 - 4.8e-35 120.8 9.5 4.8e-35 120.8 9.5 2.1 3 0 0 3 3 3 1 Rhomboid family SOG2 PF10428.9 KXH43510.1 - 0.32 10.1 7.1 0.42 9.8 7.1 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DNA_pol_B PF00136.21 KXH43511.1 - 1.7e-149 498.5 3.3 2.4e-149 498.0 3.3 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 KXH43511.1 - 2e-78 263.9 0.1 5.9e-78 262.3 0.0 1.9 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 KXH43511.1 - 4.3e-17 62.3 6.9 1.1e-16 61.0 6.9 1.8 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta RNase_H_2 PF13482.6 KXH43511.1 - 0.0054 16.7 0.2 0.055 13.5 0.2 2.5 1 1 0 1 1 1 1 RNase_H superfamily DNA_pol_B_2 PF03175.13 KXH43511.1 - 0.008 15.1 0.4 0.026 13.4 0.0 2.0 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral DNA_pol_B_exo2 PF10108.9 KXH43511.1 - 0.02 14.6 0.0 0.041 13.6 0.0 1.4 1 0 0 1 1 1 0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB C1_1 PF00130.22 KXH43511.1 - 0.094 12.6 9.6 0.05 13.5 0.9 2.7 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF1948 PF09185.10 KXH43511.1 - 0.11 12.4 1.7 0.12 12.2 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1948) ELFV_dehydrog PF00208.21 KXH43512.1 - 1e-85 287.3 4.1 1.3e-85 287.0 4.1 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 KXH43512.1 - 8.3e-52 174.5 0.0 1.6e-51 173.6 0.0 1.5 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain NAD_binding_7 PF13241.6 KXH43512.1 - 0.045 14.2 0.1 0.11 13.0 0.1 1.6 2 0 0 2 2 2 0 Putative NAD(P)-binding GMC_oxred_C PF05199.13 KXH43513.1 - 1.8e-08 35.0 0.5 7.7e-08 33.0 0.2 2.2 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_N PF00732.19 KXH43513.1 - 4.3e-06 26.3 0.0 2.1e-05 24.1 0.0 2.0 1 1 0 1 1 1 1 GMC oxidoreductase Abhydrolase_6 PF12697.7 KXH43513.1 - 0.0011 19.7 0.1 2.6 8.6 0.0 2.9 2 1 0 2 2 2 2 Alpha/beta hydrolase family DAO PF01266.24 KXH43513.1 - 0.005 16.5 0.5 0.21 11.1 0.1 3.0 2 1 1 3 3 3 1 FAD dependent oxidoreductase PGAP1 PF07819.13 KXH43513.1 - 0.0097 15.6 0.0 0.28 10.9 0.0 2.4 2 0 0 2 2 2 1 PGAP1-like protein NAD_binding_8 PF13450.6 KXH43513.1 - 0.021 15.1 0.2 0.064 13.5 0.2 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KXH43513.1 - 0.037 13.1 0.0 0.07 12.2 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.14 KXH43513.1 - 0.041 13.1 0.0 0.041 13.1 0.0 1.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Bac_rhamnosid6H PF17389.2 KXH43514.1 - 9.9e-12 44.8 0.0 1.5e-10 40.9 0.0 2.1 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain GDE_C PF06202.14 KXH43514.1 - 0.077 11.9 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Amylo-alpha-1,6-glucosidase HA2 PF04408.23 KXH43515.1 - 1.1e-16 61.0 0.2 2.8e-15 56.5 0.0 2.6 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KXH43515.1 - 9.2e-16 58.2 0.0 2.1e-15 57.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 KXH43515.1 - 8.3e-15 54.9 0.0 1.7e-14 53.9 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 KXH43515.1 - 8.8e-11 41.9 0.1 1.9e-10 40.8 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KXH43515.1 - 0.00022 21.3 0.0 0.00045 20.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit RWD PF05773.22 KXH43515.1 - 0.0023 18.2 0.1 0.0047 17.2 0.1 1.6 1 0 0 1 1 1 1 RWD domain ATPase PF06745.13 KXH43515.1 - 0.0029 17.0 0.0 0.0093 15.3 0.0 1.8 1 0 0 1 1 1 1 KaiC dsRBD2 PF17842.1 KXH43515.1 - 0.0036 17.5 0.0 0.0085 16.3 0.0 1.6 1 0 0 1 1 1 1 Double-stranded RNA binding domain 2 UBA PF00627.31 KXH43515.1 - 0.0067 16.3 0.0 5.7 7.0 0.0 2.7 2 0 0 2 2 2 2 UBA/TS-N domain AAA_29 PF13555.6 KXH43515.1 - 0.0068 16.1 0.0 0.016 14.9 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain DND1_DSRM PF14709.7 KXH43515.1 - 0.018 15.3 0.2 0.058 13.7 0.2 1.9 1 0 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 AAA_22 PF13401.6 KXH43515.1 - 0.025 14.9 1.4 0.2 11.9 1.4 2.5 1 1 0 1 1 1 0 AAA domain T2SSE PF00437.20 KXH43515.1 - 0.062 12.4 0.0 0.16 11.0 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_23 PF13476.6 KXH43515.1 - 0.071 13.6 0.8 0.3 11.6 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 KXH43515.1 - 0.1 12.2 0.0 0.22 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 KXH43515.1 - 0.14 11.5 0.0 0.3 10.4 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family InPase PF18823.1 KXH43515.1 - 0.32 10.7 2.7 0.66 9.7 2.7 1.5 1 0 0 1 1 1 0 Inorganic Pyrophosphatase IHABP4_N PF16174.5 KXH43515.1 - 4.2 8.0 10.6 0.13 12.9 1.7 2.4 2 0 0 2 2 2 0 Intracellular hyaluronan-binding protein 4 N-terminal zf-C2HE PF16278.5 KXH43516.1 - 2e-17 63.4 0.1 4.8e-17 62.1 0.1 1.7 1 0 0 1 1 1 1 C2HE / C2H2 / C2HC zinc-binding finger HIT PF01230.23 KXH43516.1 - 2.4e-16 60.2 0.2 4.5e-16 59.4 0.2 1.4 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 KXH43516.1 - 6e-16 58.9 7.2 4.1e-15 56.2 7.2 2.0 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding AT_hook PF02178.19 KXH43517.1 - 8.3e-06 25.1 44.2 0.015 15.1 4.1 6.1 5 1 1 6 6 6 4 AT hook motif TRAP_alpha PF03896.16 KXH43518.1 - 1.2e-10 41.0 0.0 1.7e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit DUF5067 PF16729.5 KXH43518.1 - 0.034 14.1 0.0 0.065 13.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5067) Cyclin_N PF00134.23 KXH43519.1 - 5.6e-44 149.0 0.2 1.2e-43 147.9 0.2 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KXH43519.1 - 6e-36 123.1 0.1 1.6e-35 121.8 0.0 1.8 2 0 0 2 2 2 1 Cyclin, C-terminal domain Grg1 PF11034.8 KXH43519.1 - 1.8 8.8 5.6 6.5 7.1 0.5 3.0 3 0 0 3 3 3 0 Glucose-repressible protein Grg1 UQ_con PF00179.26 KXH43520.1 - 2.1e-20 72.8 0.1 3e-20 72.3 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KXH43520.1 - 0.021 14.5 0.0 0.033 13.9 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic E2 family B MFS_1 PF07690.16 KXH43521.1 - 2.2e-24 86.1 32.9 2.2e-24 86.1 32.9 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH43521.1 - 4.6e-12 45.5 5.4 4.6e-12 45.5 5.4 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter Bul1_C PF04426.12 KXH43522.1 - 0.00038 20.0 0.0 0.00056 19.4 0.0 1.3 1 0 0 1 1 1 1 Bul1 C terminus Arrestin_N PF00339.29 KXH43522.1 - 0.0012 18.9 0.0 0.0067 16.5 0.0 2.4 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 KXH43522.1 - 0.0027 18.2 0.1 0.79 10.2 0.0 2.9 2 2 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Bul1_N PF04425.12 KXH43522.1 - 0.026 13.3 0.2 0.1 11.3 0.1 2.0 1 1 1 2 2 2 0 Bul1 N terminus MFS_1 PF07690.16 KXH43523.1 - 3.5e-27 95.3 18.4 3.5e-27 95.3 18.4 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH43523.1 - 9.6e-07 28.0 5.7 9.6e-07 28.0 5.7 3.0 3 2 0 3 3 3 1 Sugar (and other) transporter MFS_1_like PF12832.7 KXH43523.1 - 0.013 14.3 8.1 0.026 13.4 1.7 2.6 2 0 0 2 2 2 0 MFS_1 like family DUF3270 PF11674.8 KXH43523.1 - 0.84 9.9 4.8 0.44 10.8 1.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3270) Cupin_2 PF07883.11 KXH43524.1 - 9.9e-25 86.1 0.1 1.5e-16 59.8 0.1 2.4 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.19 KXH43524.1 - 7.2e-06 25.9 0.1 0.0046 16.9 0.1 2.4 2 0 0 2 2 2 2 AraC-like ligand binding domain Cupin_3 PF05899.12 KXH43524.1 - 0.0026 17.4 0.0 0.32 10.7 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF861) CENP-C_C PF11699.8 KXH43524.1 - 0.013 15.7 0.0 0.06 13.6 0.0 1.9 2 0 0 2 2 2 0 Mif2/CENP-C like DMSP_lyase PF16867.5 KXH43524.1 - 0.015 14.9 0.0 0.028 14.0 0.0 1.4 1 0 0 1 1 1 0 Dimethlysulfonioproprionate lyase Cupin_1 PF00190.22 KXH43524.1 - 0.02 14.5 0.0 2.3 7.8 0.0 2.4 2 0 0 2 2 2 0 Cupin ARD PF03079.14 KXH43524.1 - 0.092 12.9 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 ARD/ARD' family Fungal_trans PF04082.18 KXH43525.1 - 1.1e-06 27.9 0.0 0.026 13.6 0.0 2.5 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH43525.1 - 0.00035 20.6 0.7 0.00063 19.8 0.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_3 PF01494.19 KXH43526.1 - 8.4e-08 31.8 0.4 2.4e-07 30.3 0.4 1.8 1 1 0 1 1 1 1 FAD binding domain SE PF08491.10 KXH43526.1 - 0.0013 17.9 0.0 0.002 17.2 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase RHS_repeat PF05593.14 KXH43526.1 - 0.0048 17.4 0.1 0.012 16.1 0.1 1.6 1 0 0 1 1 1 1 RHS Repeat FAA_hydrolase PF01557.18 KXH43527.1 - 3.1e-59 200.3 0.0 3.9e-59 200.0 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family DUF3176 PF11374.8 KXH43528.1 - 1.1e-33 115.6 0.1 2.7e-33 114.4 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) YccF PF03733.13 KXH43528.1 - 8 7.3 8.1 0.63 10.8 2.6 2.1 2 0 0 2 2 2 0 Inner membrane component domain RBM39linker PF15519.6 KXH43530.1 - 0.25 12.5 0.9 0.46 11.6 0.9 1.4 1 0 0 1 1 1 0 linker between RRM2 and RRM3 domains in RBM39 protein Pex24p PF06398.11 KXH43531.1 - 3.9e-99 332.1 0.2 4.8e-99 331.8 0.2 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Herpes_LP PF03363.13 KXH43531.1 - 0.014 15.2 0.7 0.031 14.1 0.7 1.6 1 0 0 1 1 1 0 Herpesvirus leader protein Ras PF00071.22 KXH43541.1 - 6.2e-46 156.0 0.1 7.1e-46 155.8 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXH43541.1 - 3e-16 59.7 0.0 4.2e-16 59.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXH43541.1 - 2.1e-07 30.6 0.0 2.5e-07 30.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KXH43541.1 - 4.4e-06 26.4 0.0 2.6e-05 23.9 0.0 1.8 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KXH43541.1 - 0.00013 22.0 0.0 0.00021 21.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KXH43541.1 - 0.00047 20.1 0.0 0.082 12.8 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 KXH43541.1 - 0.00081 18.9 0.0 0.002 17.6 0.0 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_14 PF13173.6 KXH43541.1 - 0.015 15.4 0.0 0.023 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain WAPL PF07814.13 KXH43542.1 - 4.1e-57 193.6 0.0 6.9e-57 192.9 0.0 1.3 1 0 0 1 1 1 1 Wings apart-like protein regulation of heterochromatin UPRTase PF14681.6 KXH43543.1 - 1.4e-80 269.6 0.0 1.7e-80 269.4 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 KXH43543.1 - 0.0041 16.6 0.0 0.0063 16.0 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Elf1 PF05129.13 KXH43544.1 - 1.7e-28 98.5 0.2 2.1e-28 98.2 0.2 1.1 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like PHD_4 PF16866.5 KXH43544.1 - 0.046 13.8 0.4 0.074 13.2 0.4 1.3 1 0 0 1 1 1 0 PHD-finger GTP_CH_N PF12471.8 KXH43545.1 - 6.6e-85 283.7 0.0 9.2e-85 283.3 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.20 KXH43545.1 - 1.9e-11 43.8 0.0 5.7e-11 42.3 0.0 1.8 1 1 0 1 1 1 1 GTP cyclohydrolase II DUF4644 PF15486.6 KXH43545.1 - 0.042 13.6 1.0 0.073 12.8 1.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4644) Arfaptin PF06456.13 KXH43545.1 - 0.25 10.9 0.0 0.38 10.3 0.0 1.2 1 0 0 1 1 1 0 Arfaptin-like domain Ribosomal_S3Ae PF01015.18 KXH43547.1 - 1.1e-89 299.3 2.5 1.4e-89 299.1 2.5 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family SUI1 PF01253.22 KXH43547.1 - 0.024 15.2 0.2 0.08 13.5 0.0 2.0 2 0 0 2 2 2 0 Translation initiation factor SUI1 NEMO PF11577.8 KXH43547.1 - 0.066 13.2 0.8 0.43 10.6 0.0 2.4 2 0 0 2 2 2 0 NF-kappa-B essential modulator NEMO TipAS PF07739.13 KXH43547.1 - 0.15 12.6 0.0 2.2 8.9 0.0 2.5 2 1 1 3 3 3 0 TipAS antibiotic-recognition domain Abhydrolase_1 PF00561.20 KXH43548.1 - 8.6e-13 48.5 0.0 6.2e-07 29.3 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXH43548.1 - 0.00014 22.5 0.0 0.00019 22.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 KXH43548.1 - 0.00064 19.4 0.0 0.00082 19.1 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 KXH43548.1 - 0.00084 18.7 0.0 0.0014 17.9 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 KXH43548.1 - 0.018 14.8 0.0 0.026 14.3 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Ndr PF03096.14 KXH43548.1 - 0.1 11.3 0.0 0.15 10.7 0.0 1.3 1 0 0 1 1 1 0 Ndr family Acetyltransf_2 PF00797.17 KXH43570.1 - 1.7e-38 132.8 0.1 1.1e-37 130.1 0.1 2.0 1 1 0 1 1 1 1 N-acetyltransferase Transglut_core PF01841.19 KXH43570.1 - 0.11 12.9 0.0 1.5 9.3 0.0 2.3 2 0 0 2 2 2 0 Transglutaminase-like superfamily SKN1 PF03935.15 KXH43571.1 - 0.0013 17.2 1.8 0.0015 17.0 1.8 1.1 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Oxidored_FMN PF00724.20 KXH43572.1 - 3.5e-43 148.2 0.0 4.5e-43 147.8 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.17 KXH43572.1 - 9.3e-06 24.9 0.0 1.9e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) MTHFR PF02219.17 KXH43572.1 - 0.12 11.7 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Methylenetetrahydrofolate reductase Lactamase_B PF00753.27 KXH43573.1 - 5.8e-17 62.4 0.4 9.5e-17 61.6 0.4 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KXH43573.1 - 5.9e-07 29.2 0.3 1.3e-06 28.1 0.1 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain PH_6 PF15406.6 KXH43573.1 - 0.018 15.3 0.0 0.037 14.3 0.0 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain Glyco_hydro_127 PF07944.12 KXH43574.1 - 7e-137 457.1 0.4 7.9e-137 456.9 0.4 1.0 1 0 0 1 1 1 1 Beta-L-arabinofuranosidase, GH127 PhyH PF05721.13 KXH43575.1 - 4.7e-05 23.7 0.1 0.00049 20.4 0.1 2.1 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 KXH43575.1 - 0.011 14.5 0.1 0.038 12.8 0.0 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1479) MFS_1 PF07690.16 KXH43576.1 - 5.6e-21 74.8 38.6 5.6e-21 74.8 38.6 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily NAD_binding_10 PF13460.6 KXH43577.1 - 6.7e-09 35.9 0.0 8.4e-09 35.6 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KXH43577.1 - 3.5e-07 30.0 0.1 1.7e-06 27.8 0.1 1.8 1 1 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.24 KXH43577.1 - 0.062 13.7 0.0 0.088 13.2 0.0 1.2 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.10 KXH43577.1 - 0.067 13.1 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 KR domain Met_asp_mut_E PF06368.11 KXH43577.1 - 0.16 10.4 0.0 0.22 10.0 0.0 1.1 1 0 0 1 1 1 0 Methylaspartate mutase E chain (MutE) MFS_1 PF07690.16 KXH43578.1 - 2.9e-15 56.1 61.9 8.2e-11 41.4 28.0 3.0 1 1 2 3 3 3 3 Major Facilitator Superfamily EthD PF07110.11 KXH43579.1 - 0.0034 18.5 0.0 0.008 17.3 0.0 1.6 1 1 0 1 1 1 1 EthD domain DJ-1_PfpI PF01965.24 KXH43580.1 - 3.8e-05 23.5 0.0 6.6e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family Imm3 PF14425.6 KXH43580.1 - 0.025 14.6 0.0 0.054 13.5 0.0 1.6 1 0 0 1 1 1 0 Immunity protein Imm3 ThiJ_like PF17124.5 KXH43580.1 - 0.034 13.8 0.1 0.33 10.6 0.0 2.7 4 0 0 4 4 4 0 ThiJ/PfpI family-like Epimerase PF01370.21 KXH43581.1 - 3.8e-16 59.3 0.0 6.1e-16 58.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXH43581.1 - 3.7e-11 42.6 0.0 6.3e-11 41.8 0.0 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KXH43581.1 - 5.5e-11 42.1 0.0 7.4e-05 22.0 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein GDP_Man_Dehyd PF16363.5 KXH43581.1 - 6.5e-08 32.4 0.0 1.3e-07 31.4 0.0 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KXH43581.1 - 1.3e-06 28.4 0.1 5.1e-06 26.5 0.1 1.9 2 0 0 2 2 2 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KXH43581.1 - 1.9e-05 23.9 0.0 2.4e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 KXH43581.1 - 0.00025 20.7 0.2 0.00054 19.6 0.2 1.5 1 0 0 1 1 1 1 NmrA-like family KR PF08659.10 KXH43581.1 - 0.037 13.9 0.6 0.13 12.2 0.6 1.9 1 1 0 1 1 1 0 KR domain adh_short PF00106.25 KXH43581.1 - 0.068 12.6 0.3 0.53 9.7 0.1 2.2 2 0 0 2 2 2 0 short chain dehydrogenase NAD_binding_10 PF13460.6 KXH43582.1 - 7.4e-11 42.3 0.4 1.1e-10 41.7 0.4 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KXH43582.1 - 8.2e-11 41.9 0.6 1.1e-10 41.5 0.6 1.2 1 0 0 1 1 1 1 NmrA-like family Sacchrp_dh_NADP PF03435.18 KXH43582.1 - 8.6e-11 42.2 0.3 1.5e-10 41.4 0.3 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain GFO_IDH_MocA PF01408.22 KXH43582.1 - 8.5e-05 23.4 0.1 0.00018 22.4 0.1 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.17 KXH43582.1 - 0.0001 22.8 0.2 0.00027 21.5 0.2 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.21 KXH43582.1 - 0.00021 20.8 0.3 0.00035 20.1 0.3 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 KXH43582.1 - 0.00068 20.1 0.3 0.0011 19.4 0.3 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 KXH43582.1 - 0.00085 19.4 0.1 0.0015 18.7 0.1 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus adh_short PF00106.25 KXH43582.1 - 0.0027 17.2 0.2 0.0048 16.4 0.2 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXH43582.1 - 0.006 16.5 0.8 0.014 15.4 0.8 1.7 1 1 0 1 1 1 1 KR domain ApbA PF02558.16 KXH43582.1 - 0.0087 15.7 0.1 0.018 14.7 0.1 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.18 KXH43582.1 - 0.017 15.4 0.2 0.047 13.9 0.2 1.7 1 1 0 1 1 1 0 TrkA-N domain Shikimate_DH PF01488.20 KXH43582.1 - 0.021 14.9 0.1 0.039 14.0 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 3Beta_HSD PF01073.19 KXH43582.1 - 0.026 13.6 0.0 0.039 12.9 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family 3HCDH_N PF02737.18 KXH43582.1 - 0.045 13.6 0.1 0.11 12.4 0.1 1.8 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_4 PF07993.12 KXH43582.1 - 0.058 12.6 0.1 0.098 11.8 0.1 1.3 1 0 0 1 1 1 0 Male sterility protein THF_DHG_CYH_C PF02882.19 KXH43582.1 - 0.071 12.4 0.0 0.16 11.2 0.0 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Ldh_1_N PF00056.23 KXH43582.1 - 0.086 12.9 0.6 0.2 11.7 0.6 1.7 1 1 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain PglD_N PF17836.1 KXH43582.1 - 0.11 13.1 0.4 0.34 11.6 0.1 2.0 2 0 0 2 2 1 0 PglD N-terminal domain Polysacc_synt_2 PF02719.15 KXH43582.1 - 0.13 11.4 0.9 0.15 11.2 0.1 1.5 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Peptidase_M23_N PF18421.1 KXH43582.1 - 0.14 12.0 0.0 0.36 10.7 0.0 1.6 1 0 0 1 1 1 0 Peptidase family M23 N-terminal domain OpuAC PF04069.12 KXH43584.1 - 0.025 14.2 0.0 0.037 13.6 0.0 1.2 1 0 0 1 1 1 0 Substrate binding domain of ABC-type glycine betaine transport system SnoaL_2 PF12680.7 KXH43585.1 - 0.00049 20.7 0.0 0.00076 20.1 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like domain DUF2358 PF10184.9 KXH43585.1 - 0.028 14.7 0.0 0.044 14.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2358) zf-RING_2 PF13639.6 KXH43586.1 - 4.4e-08 33.3 7.2 4.4e-08 33.3 7.2 2.4 2 0 0 2 2 2 1 Ring finger domain FANCL_C PF11793.8 KXH43586.1 - 2.3e-06 27.7 10.2 1e-05 25.6 6.8 2.4 2 0 0 2 2 2 1 FANCL C-terminal domain zf-ANAPC11 PF12861.7 KXH43586.1 - 0.017 15.1 5.2 0.017 15.1 5.2 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 KXH43586.1 - 0.027 14.7 5.5 0.027 14.7 5.5 2.1 2 0 0 2 2 2 0 RING-H2 zinc finger domain Prok-RING_1 PF14446.6 KXH43586.1 - 0.029 14.3 4.4 0.029 14.3 4.4 2.8 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 zf-RING_5 PF14634.6 KXH43586.1 - 0.63 10.0 11.2 0.11 12.4 7.2 1.9 2 0 0 2 2 2 0 zinc-RING finger domain Dicty_REP PF05086.12 KXH43586.1 - 1 7.2 2.2 1.4 6.9 2.2 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein zf-RING_UBOX PF13445.6 KXH43586.1 - 3.5 7.7 11.0 0.095 12.7 4.3 2.0 2 0 0 2 2 2 0 RING-type zinc-finger Peptidase_S10 PF00450.22 KXH43587.1 - 2.8e-82 277.4 1.7 4e-82 276.9 1.7 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Cep3 PF16846.5 KXH43587.1 - 0.063 11.7 0.0 0.094 11.2 0.0 1.1 1 0 0 1 1 1 0 Centromere DNA-binding protein complex CBF3 subunit B TauD PF02668.16 KXH43588.1 - 3.3e-31 109.1 0.2 3.3e-31 109.1 0.2 1.4 2 0 0 2 2 2 1 Taurine catabolism dioxygenase TauD, TfdA family AftA_C PF12249.8 KXH43588.1 - 0.13 11.9 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 Arabinofuranosyltransferase A C terminal Clr5 PF14420.6 KXH43589.1 - 3e-15 56.2 2.0 6.3e-15 55.1 2.0 1.6 1 0 0 1 1 1 1 Clr5 domain MFS18 PF17352.2 KXH43591.1 - 0.021 15.2 2.2 0.021 15.2 2.2 2.3 1 1 1 2 2 2 0 Male Flower Specific protein 18 Cu-oxidase_2 PF07731.14 KXH43592.1 - 5.2e-41 139.6 9.2 5.6e-40 136.2 0.7 2.9 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 KXH43592.1 - 3e-37 127.3 3.0 9.3e-37 125.7 3.0 1.9 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase PF00394.22 KXH43592.1 - 2.7e-33 115.3 2.8 4e-32 111.5 1.3 2.5 2 0 0 2 2 2 1 Multicopper oxidase PAN_4 PF14295.6 KXH43593.1 - 7e-11 41.9 5.6 1.1e-06 28.4 0.5 2.3 1 1 1 2 2 2 2 PAN domain PAN_1 PF00024.26 KXH43593.1 - 3e-08 33.5 2.1 0.00017 21.5 0.1 2.2 1 1 1 2 2 2 2 PAN domain MANEC PF07502.14 KXH43593.1 - 8.3e-05 22.8 2.6 0.034 14.4 0.1 2.2 1 1 1 2 2 2 2 MANEC domain MFS_1 PF07690.16 KXH43594.1 - 2.7e-35 121.9 30.3 4.3e-35 121.3 30.3 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH43594.1 - 6.8e-10 38.4 18.9 2.2e-09 36.7 18.9 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter Saf_2TM PF18303.1 KXH43594.1 - 0.019 14.5 0.2 0.61 9.7 0.0 2.7 3 0 0 3 3 3 0 SAVED-fused 2TM effector domain CN_hydrolase PF00795.22 KXH43596.1 - 3e-33 115.3 0.0 6.5e-33 114.2 0.0 1.6 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase Methyltransf_2 PF00891.18 KXH43596.1 - 1e-17 64.2 0.0 1.8e-17 63.4 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 KXH43596.1 - 0.13 12.3 0.0 0.49 10.4 0.0 1.9 2 0 0 2 2 2 0 Dimerisation domain TauD PF02668.16 KXH43597.1 - 1.3e-36 126.8 0.0 1.7e-36 126.4 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family TauD PF02668.16 KXH43598.1 - 2e-45 155.7 0.1 2.9e-45 155.2 0.1 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family p450 PF00067.22 KXH43599.1 - 3.6e-38 131.5 0.0 4.7e-38 131.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 HLH PF00010.26 KXH43601.1 - 5.5e-15 55.1 0.1 1e-14 54.2 0.1 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF1387 PF07139.11 KXH43601.1 - 0.71 9.5 9.3 1.4 8.6 9.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) GREB1 PF15782.5 KXH43601.1 - 3 4.8 12.8 4.2 4.4 12.8 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SOG2 PF10428.9 KXH43602.1 - 10 5.2 13.1 11 5.0 13.1 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein GRIP PF01465.20 KXH43603.1 - 1.2e-15 57.2 0.1 3e-15 55.9 0.1 1.8 1 0 0 1 1 1 1 GRIP domain Phage_GP20 PF06810.11 KXH43603.1 - 9e-09 35.3 158.1 0.0026 17.6 6.1 11.5 3 2 6 11 11 11 6 Phage minor structural protein GP20 CENP-F_leu_zip PF10473.9 KXH43603.1 - 7.4e-07 29.3 179.9 0.0064 16.5 28.6 9.4 3 2 6 9 9 8 7 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3584 PF12128.8 KXH43603.1 - 9.8e-06 23.4 141.4 3.6e-05 21.5 24.8 5.2 3 1 2 5 5 5 3 Protein of unknown function (DUF3584) GAS PF13851.6 KXH43603.1 - 2.1e-05 24.0 166.5 0.016 14.5 15.1 9.7 3 2 7 10 10 10 6 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 KXH43603.1 - 6.1e-05 22.1 165.9 0.06 12.2 22.8 7.5 3 2 4 7 7 7 7 Spc7 kinetochore protein DUF4200 PF13863.6 KXH43603.1 - 0.0024 18.3 26.3 0.0024 18.3 26.3 11.2 5 2 5 11 11 10 2 Domain of unknown function (DUF4200) Sec2p PF06428.11 KXH43603.1 - 0.0028 17.6 11.9 0.0028 17.6 11.9 12.2 6 2 3 10 10 8 1 GDP/GTP exchange factor Sec2p Cep57_CLD_2 PF14197.6 KXH43603.1 - 0.0039 17.2 1.5 0.0039 17.2 1.5 13.5 6 3 6 12 12 9 2 Centrosome localisation domain of PPC89 Filament PF00038.21 KXH43603.1 - 0.004 16.8 151.0 0.048 13.3 20.3 9.3 3 2 5 8 8 8 4 Intermediate filament protein DHR10 PF18595.1 KXH43603.1 - 0.0056 16.7 12.0 0.0056 16.7 12.0 11.4 5 2 3 11 11 11 4 Designed helical repeat protein 10 domain HOOK PF05622.12 KXH43603.1 - 0.1 10.7 160.4 0.042 12.0 1.4 4.9 3 2 1 4 4 4 0 HOOK protein TPR_MLP1_2 PF07926.12 KXH43603.1 - 0.14 12.2 177.8 0.023 14.7 15.1 10.7 3 2 8 11 11 8 0 TPR/MLP1/MLP2-like protein MAD PF05557.13 KXH43603.1 - 1.3 7.3 160.5 0.028 12.8 34.2 5.5 3 1 3 6 6 6 0 Mitotic checkpoint protein MscS_porin PF12795.7 KXH43603.1 - 1.3 8.5 155.1 0.71 9.4 16.5 8.0 4 2 2 7 7 7 0 Mechanosensitive ion channel porin domain NPV_P10 PF05531.12 KXH43603.1 - 2.1 8.8 76.3 0.98 9.9 1.4 11.3 7 3 2 10 10 10 0 Nucleopolyhedrovirus P10 protein APG6_N PF17675.1 KXH43603.1 - 7.6 7.1 206.9 0.19 12.2 26.2 11.4 5 4 5 10 10 9 0 Apg6 coiled-coil region UPF0242 PF06785.11 KXH43603.1 - 8.2 6.5 158.7 0.074 13.2 18.4 9.8 3 2 6 9 9 9 0 Uncharacterised protein family (UPF0242) N-terminus Methyltransf_23 PF13489.6 KXH43606.1 - 2.2e-19 69.9 0.0 3.3e-19 69.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH43606.1 - 1.3e-13 51.0 0.0 1.5e-12 47.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH43606.1 - 4.4e-12 46.5 0.0 9.8e-12 45.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH43606.1 - 7.7e-09 36.1 0.0 1.8e-08 34.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH43606.1 - 2.5e-08 34.6 0.0 1.6e-07 32.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain CheR PF01739.18 KXH43606.1 - 0.0002 20.9 0.0 0.0004 19.9 0.0 1.4 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain Methyltransf_4 PF02390.17 KXH43606.1 - 0.00026 20.5 0.2 0.0014 18.2 0.0 2.2 3 0 0 3 3 3 1 Putative methyltransferase MTS PF05175.14 KXH43606.1 - 0.00056 19.5 0.0 0.0067 16.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.19 KXH43606.1 - 0.0081 16.3 0.0 0.014 15.6 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF938 PF06080.12 KXH43606.1 - 0.079 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) PrmA PF06325.13 KXH43606.1 - 0.19 11.1 0.0 0.29 10.5 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) FAD_binding_3 PF01494.19 KXH43608.1 - 6.3e-74 249.3 0.0 7.6e-74 249.0 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KXH43608.1 - 2.6e-07 30.5 0.0 0.0047 16.6 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KXH43608.1 - 0.0044 16.3 0.0 0.011 15.0 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXH43608.1 - 0.011 15.9 0.0 0.034 14.4 0.0 1.9 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXH43608.1 - 0.017 14.4 0.0 0.049 12.9 0.0 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXH43608.1 - 0.019 14.2 0.0 0.032 13.5 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.12 KXH43608.1 - 0.032 13.3 0.0 0.064 12.3 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_2 PF00890.24 KXH43608.1 - 0.065 12.3 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 KXH43608.1 - 0.087 11.5 0.0 0.15 10.8 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Sugar_tr PF00083.24 KXH43609.1 - 1.1e-99 334.3 22.5 1.3e-99 334.1 22.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH43609.1 - 1.2e-13 50.7 35.9 9.4e-10 37.9 14.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KXH43609.1 - 0.0012 17.5 15.5 0.0053 15.4 0.8 2.6 2 2 0 2 2 2 2 MFS/sugar transport protein TPR_19 PF14559.6 KXH43609.1 - 0.07 13.6 0.2 0.13 12.8 0.2 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat Pkinase_Tyr PF07714.17 KXH43614.1 - 0.21 10.8 0.0 0.85 8.8 0.0 1.9 2 0 0 2 2 2 0 Protein tyrosine kinase MPC PF03650.13 KXH43615.1 - 3.1e-47 159.3 0.6 3.1e-47 159.3 0.6 1.6 2 0 0 2 2 2 1 Mitochondrial pyruvate carriers L51_S25_CI-B8 PF05047.16 KXH43616.1 - 1.9e-08 34.1 0.0 4e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain PAM2 PF07145.15 KXH43617.1 - 0.068 12.9 0.1 0.2 11.4 0.1 1.8 1 0 0 1 1 1 0 Ataxin-2 C-terminal region DUF1687 PF07955.11 KXH43618.1 - 1.5e-33 116.0 0.3 1.9e-33 115.6 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1687) CBP PF12192.8 KXH43618.1 - 0.012 15.7 0.2 0.41 10.9 0.0 2.2 2 0 0 2 2 2 0 Fungal calcium binding protein ArsC PF03960.15 KXH43618.1 - 0.07 13.2 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 ArsC family Ribosomal_L14e PF01929.17 KXH43620.1 - 2.1e-29 101.8 1.7 2.8e-29 101.4 1.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.29 KXH43620.1 - 8.7e-05 22.3 1.6 0.00029 20.7 0.0 2.6 3 0 0 3 3 3 1 KOW motif NAC PF01849.18 KXH43621.1 - 5.8e-23 80.6 0.2 2.1e-22 78.8 0.0 2.0 2 0 0 2 2 2 1 NAC domain Cwf_Cwc_15 PF04889.12 KXH43621.1 - 2.6 7.7 15.8 4.8 6.8 6.7 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Mt_ATP-synt_D PF05873.12 KXH43622.1 - 2.6e-21 76.1 3.0 3.4e-21 75.7 3.0 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) GIDA_assoc PF13932.6 KXH43622.1 - 0.068 13.4 1.3 0.089 13.0 1.3 1.1 1 0 0 1 1 1 0 GidA associated domain T5orf172 PF10544.9 KXH43622.1 - 0.088 13.4 0.3 0.3 11.6 0.3 1.9 1 1 0 1 1 1 0 T5orf172 domain DUF148 PF02520.17 KXH43622.1 - 0.75 9.9 5.8 0.3 11.2 2.3 1.9 1 1 1 2 2 2 0 Domain of unknown function DUF148 Abhydrolase_3 PF07859.13 KXH43623.1 - 6.9e-34 117.5 0.1 1.1e-33 116.9 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXH43623.1 - 0.00036 19.9 0.0 0.00059 19.2 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KXH43623.1 - 0.00036 21.2 8.6 0.00079 20.1 7.8 1.9 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXH43623.1 - 0.046 13.4 0.2 0.07 12.8 0.2 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KXH43623.1 - 0.14 11.6 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF2920 PF11144.8 KXH43623.1 - 0.15 11.2 0.0 0.25 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) VPS28 PF03997.12 KXH43624.1 - 0.0062 16.2 0.1 0.0085 15.8 0.1 1.1 1 0 0 1 1 1 1 VPS28 protein DUF4050 PF13259.6 KXH43625.1 - 0.15 12.4 1.7 0.24 11.7 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) MFS_1 PF07690.16 KXH43626.1 - 1.2e-36 126.4 24.1 1.2e-36 126.4 24.1 2.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH43626.1 - 1.2e-11 44.1 14.5 1.2e-11 44.1 14.5 2.8 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KXH43626.1 - 0.00027 19.5 4.2 0.00027 19.5 4.2 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Thioredoxin PF00085.20 KXH43628.1 - 1.9e-06 27.8 0.0 2.9e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_9 PF14595.6 KXH43628.1 - 0.011 15.5 0.0 0.12 12.2 0.0 2.0 2 0 0 2 2 2 0 Thioredoxin Redoxin PF08534.10 KXH43628.1 - 0.019 14.7 0.0 0.026 14.2 0.0 1.2 1 0 0 1 1 1 0 Redoxin DUF953 PF06110.11 KXH43628.1 - 0.034 13.7 0.5 0.36 10.5 0.5 2.0 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) rhaM PF05336.13 KXH43629.1 - 6.4e-36 122.7 0.7 7.6e-36 122.5 0.7 1.1 1 0 0 1 1 1 1 L-rhamnose mutarotase Amidohydro_2 PF04909.14 KXH43630.1 - 3.4e-43 148.5 2.6 4.1e-43 148.2 2.6 1.1 1 0 0 1 1 1 1 Amidohydrolase bZIP_2 PF07716.15 KXH43667.1 - 4.1e-06 26.8 7.9 7.3e-06 26.0 7.9 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 KXH43667.1 - 8.3e-06 25.8 5.4 1.6e-05 24.9 5.4 1.4 1 0 0 1 1 1 1 bZIP transcription factor TTKRSYEDQ PF10212.9 KXH43667.1 - 0.0049 15.9 0.1 0.0069 15.4 0.1 1.1 1 0 0 1 1 1 1 Predicted coiled-coil domain-containing protein Fes1 PF08609.10 KXH43667.1 - 0.021 15.7 0.1 0.034 15.0 0.1 1.5 1 1 0 1 1 1 0 Nucleotide exchange factor Fes1 DUF3437 PF11919.8 KXH43668.1 - 0.037 13.9 0.0 0.19 11.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3437) IFT46_B_C PF12317.8 KXH43668.1 - 0.044 13.5 0.4 0.1 12.3 0.1 1.7 2 0 0 2 2 2 0 Intraflagellar transport complex B protein 46 C terminal WD40 PF00400.32 KXH43669.1 - 5.8e-23 80.7 23.2 1.2e-05 25.9 0.2 7.0 6 2 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXH43669.1 - 6.3e-13 48.8 5.2 2.8e-05 24.3 0.0 4.0 2 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain TFIIIC_delta PF12657.7 KXH43669.1 - 3e-05 24.0 8.6 0.016 15.2 0.2 3.0 2 2 0 2 2 2 2 Transcription factor IIIC subunit delta N-term Ge1_WD40 PF16529.5 KXH43669.1 - 0.011 14.7 1.5 1.2 8.1 0.0 3.5 2 2 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein IKI3 PF04762.12 KXH43669.1 - 0.33 8.9 3.1 5.1 4.9 0.0 2.1 2 0 0 2 2 2 0 IKI3 family PD40 PF07676.12 KXH43670.1 - 0.00085 19.2 0.4 0.0034 17.3 0.0 2.2 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat GSDH PF07995.11 KXH43670.1 - 0.039 13.2 2.2 0.25 10.6 2.0 2.3 1 1 1 2 2 2 0 Glucose / Sorbosone dehydrogenase SGL PF08450.12 KXH43670.1 - 0.056 13.0 0.0 0.097 12.2 0.0 1.4 1 0 0 1 1 1 0 SMP-30/Gluconolactonase/LRE-like region Med3 PF11593.8 KXH43703.1 - 0.042 13.0 5.8 0.044 13.0 5.8 1.0 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal adh_short PF00106.25 KXH43704.1 - 2e-12 47.0 0.0 2.5e-11 43.4 0.0 2.5 2 1 0 2 2 2 1 short chain dehydrogenase Epimerase PF01370.21 KXH43704.1 - 2.6e-06 27.1 0.0 5e-06 26.2 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KXH43704.1 - 6.1e-05 23.0 0.0 0.00021 21.3 0.0 1.8 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.6 KXH43704.1 - 0.00016 21.4 0.0 0.0031 17.1 0.0 2.5 3 0 0 3 3 3 1 Enoyl-(Acyl carrier protein) reductase E1-N PF14463.6 KXH43704.1 - 0.018 14.9 0.1 0.031 14.1 0.1 1.4 1 0 0 1 1 1 0 E1 N-terminal domain GDP_Man_Dehyd PF16363.5 KXH43704.1 - 0.023 14.1 1.4 0.035 13.5 0.0 2.0 2 1 0 2 2 2 0 GDP-mannose 4,6 dehydratase p25-alpha PF05517.12 KXH43704.1 - 0.39 10.9 7.8 0.66 10.1 7.8 1.3 1 0 0 1 1 1 0 p25-alpha CENP-Q PF13094.6 KXH43704.1 - 0.48 10.6 14.6 0.68 10.1 14.6 1.2 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit G-patch PF01585.23 KXH43705.1 - 1.2e-05 25.1 0.3 2.3e-05 24.2 0.3 1.6 1 0 0 1 1 1 1 G-patch domain LPMO_10 PF03067.15 KXH43705.1 - 0.0084 16.8 0.0 0.012 16.2 0.0 1.3 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading HIPIP PF01355.17 KXH43705.1 - 0.13 12.6 0.7 0.49 10.8 0.1 2.1 1 1 1 2 2 2 0 High potential iron-sulfur protein Sec1 PF00995.23 KXH43706.1 - 1.6e-112 377.7 0.0 2e-112 377.4 0.0 1.0 1 0 0 1 1 1 1 Sec1 family SET PF00856.28 KXH43708.1 - 5e-13 49.8 0.0 1.2e-12 48.5 0.0 1.7 1 1 0 1 1 1 1 SET domain Npa1 PF11707.8 KXH43709.1 - 5.8e-101 338.2 0.0 1.1e-100 337.3 0.0 1.5 1 0 0 1 1 1 1 Ribosome 60S biogenesis N-terminal NopRA1 PF16201.5 KXH43709.1 - 2e-61 207.1 1.4 6.4e-59 198.9 0.2 4.4 5 0 0 5 5 5 1 Nucleolar pre-ribosomal-associated protein 1 Adaptin_N PF01602.20 KXH43709.1 - 0.0046 15.6 0.0 0.24 9.9 0.0 2.9 3 0 0 3 3 3 1 Adaptin N terminal region DIM1 PF02966.16 KXH43710.1 - 2.9e-30 104.7 0.1 3.2e-30 104.6 0.1 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Sugar_tr PF00083.24 KXH43712.1 - 1.4e-90 304.3 21.7 1.7e-90 304.1 21.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH43712.1 - 2.2e-12 46.6 47.1 2.2e-09 36.7 34.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1843 PF08898.10 KXH43712.1 - 0.19 12.3 0.5 5.9 7.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) EF-hand_1 PF00036.32 KXH43713.1 - 0.017 14.7 0.6 0.041 13.4 0.6 1.7 1 0 0 1 1 1 0 EF hand EF-hand_5 PF13202.6 KXH43713.1 - 0.039 13.5 0.2 0.08 12.5 0.2 1.6 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.6 KXH43713.1 - 0.041 13.8 0.1 0.16 12.0 0.1 2.1 1 0 0 1 1 1 0 EF-hand domain EF-hand_7 PF13499.6 KXH43713.1 - 0.17 12.4 0.0 0.39 11.2 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain pair DUF1977 PF09320.11 KXH43762.1 - 6.1e-30 103.6 0.0 1.3e-29 102.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) DnaJ PF00226.31 KXH43762.1 - 1.9e-19 69.5 0.1 3.2e-19 68.8 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain Aim19 PF10315.9 KXH43763.1 - 0.0063 16.8 0.8 0.036 14.4 0.1 2.0 1 1 1 2 2 2 1 Altered inheritance of mitochondria protein 19 Fumerase PF05681.14 KXH43763.1 - 0.13 11.6 0.0 0.19 11.1 0.0 1.1 1 0 0 1 1 1 0 Fumarate hydratase (Fumerase) Y_phosphatase2 PF03162.13 KXH43764.1 - 2.1e-45 154.3 0.0 3.4e-45 153.6 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 KXH43764.1 - 3.4e-10 40.3 0.0 7.7e-10 39.1 0.0 1.6 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 KXH43764.1 - 0.0056 16.3 0.0 0.008 15.8 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 KXH43764.1 - 0.012 15.4 0.0 0.019 14.8 0.0 1.4 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Ima1_N PF09779.9 KXH43766.1 - 3.3e-38 131.6 1.7 5.9e-38 130.8 1.7 1.4 1 0 0 1 1 1 1 Ima1 N-terminal domain DZR PF12773.7 KXH43766.1 - 0.0053 16.8 2.4 0.88 9.6 0.3 2.5 2 0 0 2 2 2 2 Double zinc ribbon Alg14 PF08660.11 KXH43767.1 - 1.1e-45 155.6 0.0 2e-45 154.9 0.0 1.3 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like ThrE_2 PF12821.7 KXH43767.1 - 0.046 13.9 0.6 0.15 12.2 0.6 1.9 1 0 0 1 1 1 0 Threonine/Serine exporter, ThrE CytB6-F_Fe-S PF08802.10 KXH43767.1 - 2.7 8.1 5.2 9.7 6.3 0.0 3.2 3 0 0 3 3 3 0 Cytochrome B6-F complex Fe-S subunit MRP-S25 PF13741.6 KXH43768.1 - 4.3e-63 212.9 10.8 9.4e-60 202.0 10.8 2.1 1 1 0 1 1 1 1 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.9 KXH43768.1 - 0.48 10.7 4.9 0.45 10.8 3.2 1.9 1 1 1 2 2 2 0 Mitochondrial ribosomal protein S23 PPR_2 PF13041.6 KXH43769.1 - 9e-22 77.0 2.8 1.6e-06 28.2 0.1 5.4 4 1 1 5 5 5 5 PPR repeat family PPR PF01535.20 KXH43769.1 - 1.7e-12 46.6 9.1 9.1e-06 25.6 0.1 5.7 6 0 0 6 6 6 2 PPR repeat PPR_3 PF13812.6 KXH43769.1 - 2.4e-09 37.1 0.0 0.0012 18.8 0.0 4.2 4 0 0 4 4 4 2 Pentatricopeptide repeat domain PPR_1 PF12854.7 KXH43769.1 - 2e-08 33.8 6.8 0.0038 16.9 0.0 4.5 4 1 0 4 4 4 3 PPR repeat PPR_long PF17177.4 KXH43769.1 - 0.0012 18.3 0.3 0.033 13.5 0.1 2.9 2 1 1 3 3 3 1 Pentacotripeptide-repeat region of PRORP COX7C PF02935.16 KXH43770.1 - 1.9e-23 82.5 4.9 2.3e-23 82.2 4.9 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc rRNA_proc-arch PF13234.6 KXH43771.1 - 4.4e-86 289.2 0.0 1.3e-85 287.6 0.0 1.9 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.12 KXH43771.1 - 9.9e-49 165.1 2.3 1.9e-48 164.2 1.1 2.1 2 0 0 2 2 2 1 DSHCT (NUC185) domain DEAD PF00270.29 KXH43771.1 - 2.3e-19 69.8 0.0 1.6e-18 67.1 0.0 2.5 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXH43771.1 - 3.6e-08 33.7 0.1 1.7e-07 31.6 0.1 2.1 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXH43771.1 - 2.6e-05 24.3 0.0 7.1e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit T2SSE PF00437.20 KXH43771.1 - 0.027 13.5 0.0 0.059 12.4 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_22 PF13401.6 KXH43771.1 - 0.045 14.0 0.0 0.23 11.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 KXH43771.1 - 0.12 12.3 0.9 0.48 10.3 0.0 2.4 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea DUF2407_C PF13373.6 KXH43772.1 - 6.1e-35 120.4 0.0 9e-35 119.9 0.0 1.3 1 0 0 1 1 1 1 DUF2407 C-terminal domain DUF2407 PF10302.9 KXH43772.1 - 1e-28 99.9 0.0 1.6e-28 99.3 0.0 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.23 KXH43772.1 - 0.0014 18.3 0.0 0.0038 16.9 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD_2 PF13881.6 KXH43772.1 - 0.049 13.7 0.0 0.13 12.4 0.0 1.7 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like TT_ORF2 PF02957.15 KXH43772.1 - 1 10.3 6.9 6.4 7.7 0.2 2.7 2 1 1 3 3 3 0 TT viral ORF2 Fungal_trans_2 PF11951.8 KXH43773.1 - 7.5e-69 232.4 3.4 9.7e-69 232.0 3.4 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH43773.1 - 1.6e-08 34.5 6.7 1.6e-08 34.5 6.7 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain OPT PF03169.15 KXH43774.1 - 2.1e-169 565.1 49.4 2.4e-169 564.9 49.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DAO PF01266.24 KXH43775.1 - 3.7e-35 122.1 0.1 4.4e-35 121.9 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXH43775.1 - 5.5e-06 26.5 0.0 1.4e-05 25.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Glu_dehyd_C PF16912.5 KXH43775.1 - 0.0049 16.4 0.0 0.0096 15.4 0.0 1.4 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus Trp_halogenase PF04820.14 KXH43775.1 - 0.049 12.5 0.0 4.6 6.0 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Thi4 PF01946.17 KXH43775.1 - 0.055 12.7 0.0 0.092 12.0 0.0 1.2 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.14 KXH43775.1 - 0.12 11.6 0.0 0.71 9.0 0.0 2.1 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 KXH43775.1 - 0.23 11.5 0.0 0.4 10.7 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Zip PF02535.22 KXH43776.1 - 0.0055 16.0 0.0 0.0071 15.6 0.0 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter MFS_1 PF07690.16 KXH43778.1 - 1.5e-48 165.5 36.4 1.5e-48 165.5 36.4 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH43778.1 - 3.3e-11 42.7 22.7 1.2e-10 40.8 23.2 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_4 PF06779.14 KXH43778.1 - 2.3e-07 30.4 8.5 2.3e-07 30.4 8.5 1.8 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB MFS_3 PF05977.13 KXH43778.1 - 0.047 12.1 7.0 0.072 11.5 7.0 1.2 1 0 0 1 1 1 0 Transmembrane secretion effector REPA_OB_2 PF16900.5 KXH43779.1 - 0.052 13.5 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Replication protein A OB domain Na_H_Exchanger PF00999.21 KXH43780.1 - 1.2e-27 96.7 35.4 1e-23 83.8 21.5 3.1 3 0 0 3 3 3 3 Sodium/hydrogen exchanger family Trypan_PARP PF05887.11 KXH43780.1 - 0.0062 16.5 0.1 0.018 15.0 0.0 1.8 2 0 0 2 2 2 1 Procyclic acidic repetitive protein (PARP) Pex14_N PF04695.13 KXH43780.1 - 0.11 13.2 2.3 2.4 8.8 3.1 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Fst_toxin PF13955.6 KXH43780.1 - 0.82 9.7 0.1 0.82 9.7 0.1 3.0 3 0 0 3 3 3 0 Toxin Fst, type I toxin-antitoxin system LysM PF01476.20 KXH43781.1 - 1.7e-10 40.8 0.4 4.9e-10 39.3 0.2 1.8 2 0 0 2 2 2 1 LysM domain Thionin PF00321.17 KXH43782.1 - 0.072 13.6 0.6 0.072 13.6 0.6 1.7 2 0 0 2 2 2 0 Plant thionin DUF1936 PF09151.10 KXH43784.1 - 0.22 11.5 1.0 2.2 8.3 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1936) LRR_4 PF12799.7 KXH43786.1 - 3.2e-24 84.6 41.7 6.3e-05 23.3 5.6 8.8 3 1 3 9 9 9 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXH43786.1 - 2.9e-18 65.4 35.7 4.8e-09 35.8 1.3 7.1 3 3 5 8 8 8 7 Leucine rich repeat LRR_9 PF14580.6 KXH43786.1 - 1.8e-09 37.3 15.1 0.038 13.5 0.5 5.1 1 1 3 4 4 4 4 Leucine-rich repeat LRR_6 PF13516.6 KXH43786.1 - 4.8e-05 23.1 20.9 3 8.1 0.0 7.7 7 0 0 7 7 7 3 Leucine Rich repeat LRR_1 PF00560.33 KXH43786.1 - 0.2 12.3 27.2 35 5.5 0.5 9.5 9 1 0 9 9 9 0 Leucine Rich Repeat RabGAP-TBC PF00566.18 KXH43787.1 - 3.2e-49 167.5 0.0 5e-49 166.9 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain ECH_1 PF00378.20 KXH43788.1 - 2.2e-16 60.0 0.0 2.6e-16 59.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXH43788.1 - 5.7e-07 29.3 0.0 7.1e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 KXH43788.1 - 0.0013 18.7 0.0 0.51 10.3 0.0 2.2 2 0 0 2 2 2 2 Peptidase family S49 Glycos_transf_1 PF00534.20 KXH43789.1 - 1e-33 116.3 0.0 4.5e-32 110.9 0.0 2.2 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KXH43789.1 - 9.2e-17 61.6 0.0 1.6e-16 60.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 KXH43789.1 - 2.1e-15 57.3 0.1 5.5e-15 56.0 0.1 1.7 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KXH43789.1 - 7.8e-08 32.9 0.0 1.9e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain ALG11_N PF15924.5 KXH43789.1 - 0.00099 19.2 0.2 0.033 14.2 0.0 2.7 1 1 1 2 2 2 1 ALG11 mannosyltransferase N-terminus Glyco_trans_1_2 PF13524.6 KXH43789.1 - 0.012 15.9 0.0 0.027 14.9 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferases group 1 PRA1 PF03208.19 KXH43790.1 - 8.9e-08 31.9 2.2 1.4e-07 31.3 2.2 1.2 1 0 0 1 1 1 1 PRA1 family protein FA_desaturase PF00487.24 KXH43790.1 - 0.3 10.9 3.0 0.49 10.2 3.0 1.3 1 0 0 1 1 1 0 Fatty acid desaturase DUF755 PF05501.11 KXH43790.1 - 2.3 8.5 12.4 4.2 7.7 12.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF755) FAD_binding_3 PF01494.19 KXH43791.1 - 6.6e-20 71.6 0.6 5.8e-15 55.4 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KXH43791.1 - 1.7e-05 25.0 1.1 4.2e-05 23.7 1.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXH43791.1 - 3e-05 23.4 1.8 0.00012 21.5 1.8 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXH43791.1 - 0.00051 19.7 1.7 0.0018 17.9 0.6 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KXH43791.1 - 0.00082 18.6 2.3 0.0014 17.8 2.3 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 KXH43791.1 - 0.0078 16.8 1.9 0.0088 16.6 0.4 2.0 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KXH43791.1 - 0.0079 15.5 2.2 0.039 13.2 0.3 2.5 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.21 KXH43791.1 - 0.021 14.1 0.4 0.021 14.1 0.4 1.9 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 KXH43791.1 - 0.029 13.5 0.8 0.029 13.5 0.8 1.5 2 0 0 2 2 2 0 Glucose inhibited division protein A Trp_halogenase PF04820.14 KXH43791.1 - 0.034 13.0 1.1 0.16 10.8 0.7 2.0 2 0 0 2 2 2 0 Tryptophan halogenase FAD_oxidored PF12831.7 KXH43791.1 - 0.041 13.2 1.1 0.078 12.3 1.1 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 KXH43791.1 - 0.061 12.0 0.6 0.13 10.9 0.6 1.5 1 0 0 1 1 1 0 HI0933-like protein ApbA PF02558.16 KXH43791.1 - 0.22 11.2 2.0 0.24 11.0 0.8 1.7 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA MFS_1 PF07690.16 KXH43792.1 - 3.4e-25 88.7 38.3 2.4e-23 82.6 35.5 2.5 2 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KXH43792.1 - 4.1e-21 75.0 24.6 5.8e-21 74.6 24.6 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) PIRT PF15099.6 KXH43792.1 - 0.35 10.4 2.7 16 5.1 0.0 2.7 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family B12D PF06522.11 KXH43792.1 - 2.1 8.2 4.6 1.9 8.3 0.5 3.2 2 0 0 2 2 2 0 NADH-ubiquinone reductase complex 1 MLRQ subunit adh_short PF00106.25 KXH43794.1 - 1.3e-16 60.7 0.1 5.6e-16 58.6 0.1 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXH43794.1 - 3.2e-13 49.8 0.3 2.5e-12 46.9 0.3 2.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Lon_C PF05362.13 KXH43794.1 - 0.082 12.4 0.7 0.14 11.7 0.4 1.5 2 0 0 2 2 2 0 Lon protease (S16) C-terminal proteolytic domain NADHdh PF00146.21 KXH43794.1 - 0.22 10.8 0.0 0.29 10.4 0.0 1.1 1 0 0 1 1 1 0 NADH dehydrogenase p450 PF00067.22 KXH43795.1 - 7.5e-57 193.1 0.0 9.3e-57 192.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 adh_short_C2 PF13561.6 KXH43796.1 - 1.1e-40 139.6 1.2 2.7e-40 138.4 1.2 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXH43796.1 - 8.6e-40 136.3 0.7 1.5e-39 135.5 0.7 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXH43796.1 - 1.1e-06 28.7 1.7 1.1e-06 28.7 1.7 1.8 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KXH43796.1 - 7e-05 22.4 0.6 0.0025 17.3 0.2 2.3 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 KXH43796.1 - 0.00053 20.2 0.8 0.00096 19.4 0.8 1.3 1 0 0 1 1 1 1 TrkA-N domain ADH_zinc_N PF00107.26 KXH43796.1 - 0.001 19.1 0.7 0.0022 18.0 0.7 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.6 KXH43796.1 - 0.0013 18.7 0.5 0.0033 17.4 0.4 1.7 1 1 0 2 2 2 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KXH43796.1 - 0.0099 16.1 0.4 0.018 15.3 0.4 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain 3Beta_HSD PF01073.19 KXH43796.1 - 0.011 14.7 0.2 0.018 14.0 0.2 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KXH43796.1 - 0.012 15.0 0.4 0.034 13.5 0.1 1.8 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase 3HCDH_N PF02737.18 KXH43796.1 - 0.028 14.3 1.7 0.045 13.6 1.7 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Glyco_trans_4_3 PF12000.8 KXH43796.1 - 0.14 11.9 0.0 0.22 11.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 4 group p450 PF00067.22 KXH43797.1 - 2.7e-52 178.0 0.0 3.8e-52 177.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.25 KXH43798.1 - 8.3e-51 172.9 0.1 7.1e-34 117.4 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXH43798.1 - 7.6e-22 77.8 0.9 5.2e-20 71.8 0.5 3.3 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KXH43798.1 - 0.00075 18.9 0.0 0.0028 17.0 0.0 1.8 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 KXH43798.1 - 0.0031 17.5 0.4 0.028 14.4 0.0 2.5 2 1 1 3 3 3 1 Phosphotransferase enzyme family Fungal_trans PF04082.18 KXH43799.1 - 3.5e-11 42.6 0.0 4.3e-11 42.3 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3973 PF13119.6 KXH43799.1 - 0.14 12.3 0.1 0.39 10.8 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3973) FMN_bind_2 PF04299.12 KXH43800.1 - 9.5e-08 31.9 0.0 2.3e-07 30.7 0.0 1.6 2 0 0 2 2 2 1 Putative FMN-binding domain BPL_LplA_LipB PF03099.19 KXH43801.1 - 1e-05 25.4 0.0 2.4e-05 24.3 0.0 1.6 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Chorismate_synt PF01264.21 KXH43802.1 - 1.8e-135 450.9 0.0 2e-135 450.7 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase Peptidase_M24 PF00557.24 KXH43803.1 - 5.9e-06 26.1 0.0 1.1e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Glyco_hydro_71 PF03659.14 KXH43804.1 - 9.8e-135 449.2 6.3 9.8e-135 449.2 6.3 1.9 2 0 0 2 2 2 2 Glycosyl hydrolase family 71 Tyrosinase PF00264.20 KXH43805.1 - 5.9e-45 154.3 3.4 5.9e-45 154.3 3.4 1.6 2 0 0 2 2 2 1 Common central domain of tyrosinase Tyosinase_C PF18132.1 KXH43805.1 - 4e-37 127.6 0.0 8.4e-37 126.6 0.0 1.6 1 0 0 1 1 1 1 Tyosinase C-terminal domain Fungal_trans_2 PF11951.8 KXH43811.1 - 8.1e-60 202.6 0.0 1e-59 202.3 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH43811.1 - 0.9 9.7 4.1 2.5 8.3 4.1 1.8 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXH43812.1 - 8.6e-26 90.5 0.0 5.2e-24 84.7 0.0 2.4 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH43812.1 - 1.8e-08 34.3 9.4 3.3e-08 33.5 9.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mito_carr PF00153.27 KXH43813.1 - 6.1e-43 144.7 8.2 1.7e-16 59.9 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Biotin_lipoyl PF00364.22 KXH43870.1 - 6.8e-19 67.5 0.9 1.3e-18 66.6 0.9 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 KXH43870.1 - 3.5e-06 27.3 0.1 3.5e-06 27.3 0.1 2.2 2 0 0 2 2 2 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 KXH43870.1 - 0.00039 20.2 0.0 0.0036 17.1 0.0 2.4 2 0 0 2 2 2 1 Biotin-lipoyl like HlyD_3 PF13437.6 KXH43870.1 - 0.0048 17.6 0.1 0.38 11.5 0.0 2.8 1 1 1 2 2 2 1 HlyD family secretion protein DUF1631 PF07793.11 KXH43870.1 - 5.5 5.3 9.4 12 4.1 9.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1631) zf-HC5HC2H_2 PF13832.6 KXH43871.1 - 3e-33 114.3 7.7 3e-33 114.3 7.7 2.5 2 0 0 2 2 2 1 PHD-zinc-finger like domain EPL1 PF10513.9 KXH43871.1 - 3.7e-26 92.4 0.0 3.7e-26 92.4 0.0 2.7 3 0 0 3 3 3 1 Enhancer of polycomb-like zf-HC5HC2H PF13771.6 KXH43871.1 - 5.2e-26 90.7 7.6 5.2e-26 90.7 7.6 2.7 3 0 0 3 3 3 1 PHD-like zinc-binding domain PHD_2 PF13831.6 KXH43871.1 - 3.4e-14 52.1 1.9 3.4e-14 52.1 1.9 2.4 2 0 0 2 2 2 1 PHD-finger PHD PF00628.29 KXH43871.1 - 2e-09 37.2 23.5 1.3e-08 34.6 9.5 2.7 2 0 0 2 2 2 2 PHD-finger zf-PHD-like PF15446.6 KXH43871.1 - 1.9 8.1 12.9 0.017 14.7 1.6 2.4 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain Aldolase_II PF00596.21 KXH43904.1 - 1.1e-40 139.5 0.0 1.4e-40 139.3 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Pkinase PF00069.25 KXH43905.1 - 3.9e-06 26.4 0.0 6.7e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain tRNA-synt_2 PF00152.20 KXH43907.1 - 3.5e-70 236.6 0.0 4.4e-70 236.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) Pre-PUA PF17832.1 KXH43908.1 - 1.4e-21 77.0 2.1 1.9e-21 76.5 2.1 1.2 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 KXH43908.1 - 8e-14 51.4 0.1 4.5e-13 49.0 0.1 2.0 1 1 0 1 1 1 1 PUA domain Inhibitor_I78 PF11720.8 KXH43909.1 - 1.7e-10 40.8 0.0 2e-10 40.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase inhibitor I78 family potato_inhibit PF00280.18 KXH43909.1 - 0.00022 21.9 0.1 0.00028 21.5 0.1 1.3 1 1 0 1 1 1 1 Potato inhibitor I family DUF2500 PF10694.9 KXH43910.1 - 0.043 14.3 0.3 0.48 10.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2500) TPP_enzyme_N PF02776.18 KXH43911.1 - 2.1e-54 183.7 0.1 1.1e-51 174.9 0.0 2.5 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KXH43911.1 - 8.2e-51 171.8 0.2 1.5e-49 167.7 0.2 2.5 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KXH43911.1 - 1.8e-39 134.6 0.4 4.4e-39 133.3 0.4 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain DUF4957 PF16318.5 KXH43913.1 - 0.052 13.5 0.0 0.09 12.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4957) NIR_SIR_ferr PF03460.17 KXH43913.1 - 0.096 12.6 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Nitrite/Sulfite reductase ferredoxin-like half domain Pkinase PF00069.25 KXH43915.1 - 1.2e-53 182.2 0.0 1.6e-53 181.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXH43915.1 - 3.6e-31 108.4 0.0 4.6e-31 108.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXH43915.1 - 2.7e-05 23.7 0.0 0.00034 20.0 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KXH43915.1 - 0.00069 19.6 0.0 0.0021 18.0 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KXH43915.1 - 0.0027 17.1 0.0 0.0044 16.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KXH43915.1 - 0.0049 15.7 0.0 0.007 15.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 KXH43915.1 - 0.052 12.5 0.0 0.079 11.9 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain FTA2 PF13095.6 KXH43915.1 - 0.058 13.0 0.0 0.96 9.0 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Choline_kinase PF01633.20 KXH43915.1 - 0.19 11.3 0.0 0.33 10.5 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pex14_N PF04695.13 KXH43931.1 - 6e-35 121.2 11.3 6e-35 121.2 11.3 4.0 2 2 1 3 3 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Golgin_A5 PF09787.9 KXH43931.1 - 0.0013 18.2 10.0 0.0023 17.5 10.0 1.3 1 0 0 1 1 1 1 Golgin subfamily A member 5 CR6_interact PF10147.9 KXH43931.1 - 0.007 16.1 2.6 0.0097 15.6 2.6 1.3 1 0 0 1 1 1 1 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 Prominin PF05478.11 KXH43931.1 - 0.066 11.2 3.7 0.092 10.7 3.7 1.2 1 0 0 1 1 1 0 Prominin UPF0242 PF06785.11 KXH43931.1 - 0.075 13.1 7.4 0.12 12.4 7.4 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF3584 PF12128.8 KXH43931.1 - 0.11 10.0 10.2 0.16 9.4 10.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Plasmid_RAQPRD PF09686.10 KXH43931.1 - 0.23 11.7 3.5 0.56 10.5 1.8 2.4 1 1 1 2 2 2 0 Plasmid protein of unknown function (Plasmid_RAQPRD) DUF572 PF04502.13 KXH43931.1 - 0.23 11.0 8.6 0.35 10.4 8.6 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) Baculo_PEP_C PF04513.12 KXH43931.1 - 0.29 11.2 8.8 2.9 7.9 2.4 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1043 PF06295.12 KXH43931.1 - 0.31 11.1 10.7 0.078 13.0 5.9 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1043) LMBR1 PF04791.16 KXH43931.1 - 0.34 9.8 0.7 0.43 9.4 0.7 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein ISG65-75 PF11727.8 KXH43931.1 - 0.39 9.9 6.6 0.63 9.2 6.6 1.3 1 0 0 1 1 1 0 Invariant surface glycoprotein DUF16 PF01519.16 KXH43931.1 - 0.43 11.1 9.3 4.3 7.9 4.8 2.5 2 0 0 2 2 2 0 Protein of unknown function DUF16 DUF948 PF06103.11 KXH43931.1 - 0.47 10.7 5.0 0.31 11.3 0.2 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) V_ATPase_I PF01496.19 KXH43931.1 - 0.94 7.3 3.0 1.3 6.8 3.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMPIT PF07851.13 KXH43931.1 - 1.5 8.0 6.8 2.7 7.1 6.8 1.4 1 0 0 1 1 1 0 TMPIT-like protein zf-C4H2 PF10146.9 KXH43931.1 - 1.7 8.9 18.6 0.011 16.1 6.6 2.3 2 0 0 2 2 2 0 Zinc finger-containing protein Nup88 PF10168.9 KXH43931.1 - 2.1 6.1 10.6 3.1 5.5 10.6 1.1 1 0 0 1 1 1 0 Nuclear pore component Csm1_N PF18504.1 KXH43931.1 - 4.5 7.7 11.0 1.7 9.1 6.4 2.4 1 1 2 3 3 3 0 Csm1 N-terminal domain Spc7 PF08317.11 KXH43931.1 - 8.6 5.1 14.8 16 4.2 14.8 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF1664 PF07889.12 KXH43931.1 - 9.5 6.3 8.8 9.1 6.3 5.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Ndc80_HEC PF03801.13 KXH43932.1 - 1.5e-60 203.2 0.3 3.1e-60 202.3 0.3 1.5 1 0 0 1 1 1 1 HEC/Ndc80p family Spc7 PF08317.11 KXH43932.1 - 3.9e-05 22.7 11.2 3.9e-05 22.7 11.2 3.3 4 0 0 4 4 4 2 Spc7 kinetochore protein DHR10 PF18595.1 KXH43932.1 - 6.3e-05 23.0 14.5 6.3e-05 23.0 14.5 3.4 3 0 0 3 3 3 2 Designed helical repeat protein 10 domain Filament PF00038.21 KXH43932.1 - 0.0019 17.8 42.4 0.047 13.3 15.6 3.2 2 1 0 2 2 2 2 Intermediate filament protein NPV_P10 PF05531.12 KXH43932.1 - 0.0095 16.4 8.6 1.1 9.8 0.8 4.0 2 1 1 3 3 3 2 Nucleopolyhedrovirus P10 protein Ntox28 PF15605.6 KXH43932.1 - 0.011 15.9 1.3 0.011 15.9 1.3 4.2 3 2 2 5 5 5 0 Bacterial toxin 28 FliJ PF02050.16 KXH43932.1 - 0.013 15.7 5.2 0.013 15.7 5.2 3.7 4 1 1 5 5 4 0 Flagellar FliJ protein DUF5595 PF18077.1 KXH43932.1 - 0.014 15.5 4.8 0.014 15.5 4.8 5.5 5 2 1 6 6 4 0 Domain of unknown function (DUF5595) TPR_MLP1_2 PF07926.12 KXH43932.1 - 0.092 12.8 41.9 0.034 14.2 10.8 3.8 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein Lebercilin PF15619.6 KXH43932.1 - 0.096 12.3 34.3 0.34 10.5 10.1 3.5 3 0 0 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease Fungal_TACC PF12709.7 KXH43932.1 - 0.15 12.5 27.4 0.19 12.2 0.2 5.3 4 2 2 6 6 5 0 Fungal Transforming acidic coiled-coil (TACC) proteins Uso1_p115_C PF04871.13 KXH43932.1 - 0.2 12.0 40.8 0.12 12.8 11.4 4.1 2 1 3 5 5 5 0 Uso1 / p115 like vesicle tethering protein, C terminal region FlxA PF14282.6 KXH43932.1 - 0.23 11.4 19.8 10 6.2 0.0 4.4 3 1 0 4 4 4 0 FlxA-like protein APG6_N PF17675.1 KXH43932.1 - 0.46 11.0 51.5 0.13 12.8 13.4 4.4 2 1 2 4 4 4 0 Apg6 coiled-coil region DUF2935 PF11155.8 KXH43932.1 - 0.48 10.8 4.2 1 9.7 0.0 3.2 2 2 0 2 2 2 0 Domain of unknown function (DUF2935) Phage_GP20 PF06810.11 KXH43932.1 - 1.1 9.0 28.2 1.2 9.0 8.4 4.2 2 1 2 4 4 4 0 Phage minor structural protein GP20 DUF4407 PF14362.6 KXH43932.1 - 2.2 7.6 27.0 0.37 10.1 5.8 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) GAS PF13851.6 KXH43932.1 - 6.5 6.0 41.4 0.57 9.5 11.2 3.5 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding Prominin PF05478.11 KXH43932.1 - 6.9 4.5 17.8 3.1 5.6 6.2 2.2 2 0 0 2 2 2 0 Prominin STAT_alpha PF01017.20 KXH43932.1 - 7.5 6.4 25.5 0.27 11.1 3.9 2.8 3 0 0 3 3 3 0 STAT protein, all-alpha domain CALCOCO1 PF07888.11 KXH43932.1 - 7.6 5.3 38.1 0.15 10.9 15.8 2.3 2 0 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like V_ATPase_I PF01496.19 KXH43932.1 - 9.2 4.0 21.7 0.5 8.2 5.1 2.2 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DUF16 PF01519.16 KXH43932.1 - 9.4 6.8 25.4 0.15 12.5 5.1 3.4 3 2 1 4 4 3 0 Protein of unknown function DUF16 Lactamase_B_2 PF12706.7 KXH43934.1 - 1.1e-27 96.9 0.0 4.1e-26 91.7 0.0 2.2 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KXH43934.1 - 1.4e-08 34.8 0.0 2.5e-08 34.0 0.0 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KXH43934.1 - 0.034 14.2 2.7 0.17 11.8 2.4 2.2 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily HET PF06985.11 KXH43935.1 - 1.2e-25 90.5 0.0 2.3e-25 89.6 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) EHN PF06441.12 KXH43936.1 - 1.4e-27 96.2 0.0 2.7e-27 95.3 0.0 1.5 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 KXH43936.1 - 0.00023 20.9 0.2 0.0004 20.1 0.2 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Fasciclin PF02469.22 KXH43938.1 - 1.7e-30 105.9 0.1 1.1e-15 58.0 0.0 2.2 2 0 0 2 2 2 2 Fasciclin domain VIT1 PF01988.19 KXH43939.1 - 1.5e-62 211.3 4.9 2.1e-62 210.8 4.9 1.2 1 0 0 1 1 1 1 VIT family SLATT_fungal PF18142.1 KXH43939.1 - 0.058 13.4 0.1 0.13 12.3 0.1 1.7 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain DNA_pol_alpha_N PF12254.8 KXH43940.1 - 0.048 13.7 0.0 0.072 13.2 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase alpha subunit p180 N terminal Glyco_hydro_47 PF01532.20 KXH43941.1 - 5.8e-142 473.8 0.0 6.6e-142 473.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Rad10 PF03834.14 KXH43942.1 - 5.9e-47 158.4 0.0 8.1e-47 158.0 0.0 1.2 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) UIM PF02809.20 KXH43942.1 - 4.4 7.4 6.3 0.74 9.9 1.5 2.3 2 0 0 2 2 2 0 Ubiquitin interaction motif MR_MLE_C PF13378.6 KXH43945.1 - 2.8e-57 193.8 0.0 4.3e-57 193.2 0.0 1.2 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 KXH43945.1 - 0.013 15.8 0.0 0.035 14.3 0.0 1.7 2 0 0 2 2 2 0 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MAAL_C PF07476.11 KXH43945.1 - 0.02 14.1 0.0 0.032 13.4 0.0 1.3 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus Spermine_synth PF01564.17 KXH43946.1 - 7.2e-08 32.1 0.0 3e-06 26.8 0.0 2.3 2 0 0 2 2 2 1 Spermine/spermidine synthase domain Methyltransf_23 PF13489.6 KXH43946.1 - 8.6e-06 25.7 0.0 2.1e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH43946.1 - 0.0088 16.7 0.0 0.017 15.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH43946.1 - 0.05 14.3 0.0 0.14 12.8 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Pyridox_ox_2 PF12900.7 KXH43947.1 - 2.1e-35 121.8 0.0 3.3e-35 121.1 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase ABC_tran PF00005.27 KXH43950.1 - 1.1e-48 165.2 0.9 1e-22 81.2 0.0 3.3 3 0 0 3 3 3 2 ABC transporter ABC_tran_Xtn PF12848.7 KXH43950.1 - 1.8e-20 72.8 7.9 1.8e-20 72.8 7.9 4.0 4 1 0 4 4 3 1 ABC transporter AAA_21 PF13304.6 KXH43950.1 - 2.3e-17 63.8 1.1 0.0014 18.5 0.0 4.5 3 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KXH43950.1 - 2.5e-11 43.4 1.7 0.0039 16.7 0.0 4.5 4 0 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 KXH43950.1 - 3.4e-07 30.2 0.1 0.0011 18.7 0.1 3.6 3 1 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.23 KXH43950.1 - 5e-07 29.8 0.1 0.016 15.3 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_18 PF13238.6 KXH43950.1 - 1e-06 29.3 0.2 0.045 14.3 0.0 3.3 3 0 0 3 3 2 2 AAA domain AAA_29 PF13555.6 KXH43950.1 - 2.2e-06 27.3 0.2 0.055 13.2 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KXH43950.1 - 5.5e-06 26.4 1.6 0.11 12.3 0.1 3.2 2 1 0 3 3 3 2 RsgA GTPase AAA_23 PF13476.6 KXH43950.1 - 8.5e-06 26.4 17.9 0.0043 17.6 0.1 4.7 5 0 0 5 5 5 2 AAA domain AAA_16 PF13191.6 KXH43950.1 - 1e-05 26.0 1.8 0.016 15.6 0.1 2.9 3 0 0 3 3 2 2 AAA ATPase domain AAA_33 PF13671.6 KXH43950.1 - 3e-05 24.2 0.0 0.25 11.5 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.6 KXH43950.1 - 4.8e-05 23.2 1.5 0.56 9.9 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.6 KXH43950.1 - 9.3e-05 22.7 0.1 0.55 10.5 0.1 3.1 3 1 0 3 3 2 2 AAA domain AAA PF00004.29 KXH43950.1 - 0.00017 22.0 0.0 0.13 12.7 0.0 3.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 KXH43950.1 - 0.00044 20.5 2.5 0.14 12.4 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 KXH43950.1 - 0.00049 20.1 0.2 1.7 8.7 0.0 3.2 3 0 0 3 3 2 2 AAA domain MeaB PF03308.16 KXH43950.1 - 0.0019 17.2 0.6 2.2 7.2 0.0 3.0 3 0 0 3 3 3 2 Methylmalonyl Co-A mutase-associated GTPase MeaB RNA_helicase PF00910.22 KXH43950.1 - 0.003 17.9 0.0 1.8 9.0 0.0 2.6 2 0 0 2 2 2 1 RNA helicase NACHT PF05729.12 KXH43950.1 - 0.0034 17.3 0.1 4.3 7.2 0.0 2.7 2 0 0 2 2 2 1 NACHT domain NTPase_1 PF03266.15 KXH43950.1 - 0.0055 16.6 0.1 0.61 10.0 0.1 2.7 2 0 0 2 2 2 1 NTPase cobW PF02492.19 KXH43950.1 - 0.0059 16.2 0.6 1.2 8.7 0.5 2.6 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.7 KXH43950.1 - 0.006 16.1 0.0 3.7 7.0 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region Roc PF08477.13 KXH43950.1 - 0.0074 16.5 0.1 5.6 7.2 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_15 PF13175.6 KXH43950.1 - 0.01 15.6 0.7 0.095 12.4 0.2 4.7 4 1 1 5 5 5 0 AAA ATPase domain Dynamin_N PF00350.23 KXH43950.1 - 0.012 15.7 7.2 0.78 9.8 0.0 4.2 4 1 0 4 4 4 0 Dynamin family MobB PF03205.14 KXH43950.1 - 0.015 15.2 0.6 0.3 11.0 0.2 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NB-ARC PF00931.22 KXH43950.1 - 0.02 14.1 0.1 3.3 6.8 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain AAA_5 PF07728.14 KXH43950.1 - 0.021 14.8 0.3 7 6.6 0.0 3.1 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Rad17 PF03215.15 KXH43950.1 - 0.048 13.6 0.5 4.8 7.1 0.0 3.3 3 1 0 3 3 3 0 Rad17 P-loop domain ATP-synt_ab PF00006.25 KXH43950.1 - 0.048 13.3 0.1 4.7 6.8 0.0 2.6 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain 5_3_exonuc_N PF02739.16 KXH43950.1 - 0.059 13.3 0.0 0.96 9.3 0.0 2.4 2 0 0 2 2 2 0 5'-3' exonuclease, N-terminal resolvase-like domain SRP54 PF00448.22 KXH43950.1 - 0.062 12.9 1.9 3.8 7.1 0.0 3.5 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain Zeta_toxin PF06414.12 KXH43950.1 - 0.072 12.4 1.1 3.1 7.0 0.1 3.2 3 0 0 3 3 3 0 Zeta toxin TsaE PF02367.17 KXH43950.1 - 0.078 13.0 0.0 4.7 7.2 0.0 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE GTP_EFTU PF00009.27 KXH43950.1 - 0.13 11.7 1.5 16 5.0 0.0 3.3 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain DUF4647 PF15504.6 KXH43950.1 - 0.25 10.4 4.3 5 6.1 0.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4647) DUF87 PF01935.17 KXH43950.1 - 0.32 11.0 8.3 0.71 9.9 0.0 3.8 4 0 0 4 4 4 0 Helicase HerA, central domain ATP_bind_1 PF03029.17 KXH43950.1 - 0.5 10.1 1.8 35 4.1 0.2 3.0 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein AAA_17 PF13207.6 KXH43950.1 - 0.98 9.8 7.1 21 5.5 0.3 3.8 4 0 0 4 4 3 0 AAA domain AAA_27 PF13514.6 KXH43950.1 - 6.4 6.3 0.0 5 6.7 0.0 4.1 6 0 0 6 6 4 0 AAA domain Tubulin PF00091.25 KXH43951.1 - 1.6e-68 230.8 0.0 4.3e-68 229.4 0.0 1.6 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KXH43951.1 - 8.9e-43 145.5 0.1 1.4e-42 144.8 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 KXH43951.1 - 1.5e-05 25.3 0.0 5.4e-05 23.5 0.0 1.9 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 KXH43951.1 - 0.0039 16.9 0.0 0.0071 16.0 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 KXH43951.1 - 0.0046 16.2 0.0 0.024 13.8 0.0 1.9 2 0 0 2 2 2 1 Tubulin like Ribosomal_L6 PF00347.23 KXH43952.1 - 8.6e-21 74.4 0.0 1.1e-08 35.6 0.0 3.2 2 2 1 3 3 3 2 Ribosomal protein L6 Inositol_P PF00459.25 KXH43953.1 - 1.8e-49 168.7 2.3 4.6e-49 167.4 2.3 1.6 1 1 0 1 1 1 1 Inositol monophosphatase family DUF2630 PF10944.8 KXH43953.1 - 0.0037 17.7 0.1 0.0069 16.8 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2630) SopA_C PF13979.6 KXH43953.1 - 0.055 13.2 0.1 0.095 12.4 0.1 1.3 1 0 0 1 1 1 0 SopA-like catalytic domain Complex1_LYR_2 PF13233.6 KXH43954.1 - 1e-22 80.6 0.3 1.4e-22 80.2 0.3 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 KXH43954.1 - 0.056 13.5 1.6 0.11 12.5 1.0 1.8 1 1 1 2 2 2 0 Complex 1 protein (LYR family) Aha1_N PF09229.11 KXH43956.1 - 8.6e-42 142.6 0.8 1.7e-41 141.6 0.8 1.5 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 KXH43956.1 - 7.5e-18 65.0 0.3 1.6e-17 63.9 0.3 1.6 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein DHHC PF01529.20 KXH43957.1 - 1.9e-31 108.9 1.5 1.9e-31 108.9 1.5 2.8 2 1 0 2 2 2 1 DHHC palmitoyltransferase Rap1_C PF11626.8 KXH43958.1 - 8.9e-21 73.8 1.0 8.1e-20 70.7 0.0 2.8 3 0 0 3 3 3 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_2 PF08914.11 KXH43958.1 - 1.3e-15 57.3 4.8 4.2e-12 46.0 0.2 3.0 3 0 0 3 3 3 2 Rap1 Myb domain BRCT_2 PF16589.5 KXH43958.1 - 7.1e-11 42.4 0.0 1.3e-10 41.5 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain ARID PF01388.21 KXH43958.1 - 2.3e-05 25.0 0.0 5.3e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain Rap1-DNA-bind PF09197.10 KXH43958.1 - 6.6e-05 23.5 8.2 0.011 16.3 0.1 3.3 3 0 0 3 3 3 2 Rap1, DNA-binding DNA_pol_phi PF04931.13 KXH43958.1 - 0.064 11.4 7.0 0.13 10.3 7.0 1.4 1 0 0 1 1 1 0 DNA polymerase phi POX PF07526.11 KXH43958.1 - 0.56 10.8 2.8 1.1 9.9 0.5 2.4 2 0 0 2 2 2 0 Associated with HOX CN_hydrolase PF00795.22 KXH43959.1 - 7.5e-32 110.7 0.0 1.1e-31 110.1 0.0 1.2 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase Tht1 PF04163.12 KXH43960.1 - 5e-10 38.8 2.1 8.8e-10 38.0 2.1 1.3 1 1 0 1 1 1 1 Tht1-like nuclear fusion protein Snapin_Pallidin PF14712.6 KXH43960.1 - 0.0034 17.8 8.6 0.3 11.6 3.8 2.9 2 1 0 2 2 2 2 Snapin/Pallidin Vps54_N PF10475.9 KXH43960.1 - 0.0084 15.4 3.1 0.05 12.9 0.5 2.6 1 1 1 3 3 3 1 Vacuolar-sorting protein 54, of GARP complex DUF2884 PF11101.8 KXH43960.1 - 0.013 15.0 0.8 0.013 15.0 0.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2884) DASH_Duo1 PF08651.10 KXH43960.1 - 0.078 12.8 0.4 3.6 7.4 0.1 2.9 2 1 1 3 3 3 0 DASH complex subunit Duo1 KxDL PF10241.9 KXH43960.1 - 0.11 12.7 2.8 0.95 9.8 0.3 2.7 2 1 0 2 2 2 0 Uncharacterized conserved protein Laminin_II PF06009.12 KXH43960.1 - 0.12 12.4 6.7 0.18 11.8 2.2 2.5 2 1 1 3 3 3 0 Laminin Domain II DUF1664 PF07889.12 KXH43960.1 - 0.28 11.2 6.7 2.3 8.3 1.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) DUF2408 PF10303.9 KXH43960.1 - 1 10.0 6.7 0.82 10.2 2.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) Apolipoprotein PF01442.18 KXH43960.1 - 1.3 8.8 13.8 8.9 6.1 13.9 2.2 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain BLOC1_2 PF10046.9 KXH43960.1 - 3.8 7.9 8.5 3.1 8.2 0.9 3.0 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FliD_C PF07195.12 KXH43960.1 - 7.1 6.0 8.0 9.7 5.5 0.4 2.8 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus Prominin PF05478.11 KXH43960.1 - 9.4 4.0 9.9 15 3.4 0.5 2.0 1 1 1 2 2 2 0 Prominin LysM PF01476.20 KXH43961.1 - 0.0025 17.8 0.0 0.0038 17.3 0.0 1.3 1 0 0 1 1 1 1 LysM domain HLH PF00010.26 KXH43962.1 - 2.8e-16 59.2 0.0 6e-16 58.1 0.0 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain SLX9 PF15341.6 KXH43962.1 - 1.9 8.9 9.4 0.92 9.9 6.0 2.2 2 1 1 3 3 3 0 Ribosome biogenesis protein SLX9 Peptidase_M24 PF00557.24 KXH43963.1 - 2.6e-48 164.5 0.0 4e-48 163.9 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 KXH43963.1 - 2.8e-38 130.4 0.0 4.4e-38 129.8 0.0 1.3 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Dfp1_Him1_M PF08630.10 KXH43964.1 - 2e-37 128.2 0.0 6.1e-37 126.7 0.0 1.9 1 0 0 1 1 1 1 Dfp1/Him1, central region zf-DBF PF07535.12 KXH43964.1 - 7.6e-22 77.2 0.6 1.3e-21 76.4 0.6 1.4 1 0 0 1 1 1 1 DBF zinc finger Tropomyosin_1 PF12718.7 KXH43964.1 - 0.02 15.0 0.3 0.074 13.2 0.3 1.9 1 0 0 1 1 1 0 Tropomyosin like Lyase_aromatic PF00221.19 KXH43965.1 - 1.9e-153 511.5 2.6 2.4e-153 511.1 2.6 1.1 1 0 0 1 1 1 1 Aromatic amino acid lyase PFK PF00365.20 KXH43965.1 - 0.023 14.1 0.0 0.19 11.0 0.0 2.1 2 0 0 2 2 2 0 Phosphofructokinase T2SS_PulS_OutS PF09691.10 KXH43965.1 - 0.1 12.8 1.3 0.21 11.8 1.3 1.5 1 0 0 1 1 1 0 Type II secretion system pilotin lipoprotein (PulS_OutS) APG12 PF04110.13 KXH43966.1 - 5.1e-28 97.3 0.0 6.4e-28 97.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.16 KXH43966.1 - 8.2e-07 29.2 0.0 1e-06 28.9 0.0 1.2 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like Pantoate_transf PF02548.15 KXH43967.1 - 3.1e-106 354.5 0.4 3.6e-106 354.3 0.4 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 KXH43967.1 - 1.5e-09 37.6 0.5 3.1e-09 36.7 0.1 1.6 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase DUF4861 PF16153.5 KXH43967.1 - 0.016 14.2 0.0 0.023 13.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4861) UQ_con PF00179.26 KXH43968.1 - 5.8e-35 120.0 0.1 7e-35 119.7 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF572 PF04502.13 KXH43969.1 - 2.7e-71 240.9 0.0 3.1e-71 240.7 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) FlgN PF05130.12 KXH43969.1 - 0.55 10.7 3.8 1.7 9.1 3.7 1.8 1 1 1 2 2 2 0 FlgN protein Fungal_trans PF04082.18 KXH43970.1 - 6.4e-21 74.6 0.1 1.2e-20 73.6 0.1 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH43970.1 - 0.0089 16.1 7.3 0.016 15.3 7.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cu_bind_like PF02298.17 KXH43972.1 - 0.087 12.9 0.1 0.34 11.0 0.1 1.9 1 1 0 1 1 1 0 Plastocyanin-like domain Cas_csx3 PF09620.10 KXH43972.1 - 0.16 11.9 0.0 0.25 11.3 0.0 1.3 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_csx3) GST_N_3 PF13417.6 KXH43973.1 - 1.9e-18 66.7 0.0 3.8e-18 65.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KXH43973.1 - 4e-17 62.3 0.2 8.6e-17 61.2 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KXH43973.1 - 4.7e-07 29.7 0.3 1e-06 28.7 0.3 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KXH43973.1 - 1.1e-06 28.9 0.1 2.1e-06 28.0 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_5 PF16865.5 KXH43973.1 - 0.0022 18.5 0.0 0.0041 17.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KXH43973.1 - 0.029 14.6 0.0 0.073 13.3 0.0 1.7 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KXH43973.1 - 0.13 12.4 0.0 0.27 11.5 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain P5CR_dimer PF14748.6 KXH43974.1 - 5.8e-29 100.4 1.5 1.1e-28 99.4 0.8 1.9 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 KXH43974.1 - 3.9e-15 56.2 0.0 8.8e-15 55.1 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ThiF PF00899.21 KXH43974.1 - 0.062 12.7 0.2 0.88 8.9 0.1 2.2 2 0 0 2 2 2 0 ThiF family DUF1772 PF08592.11 KXH43975.1 - 0.017 15.4 3.7 0.046 14.0 3.7 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) Aldedh PF00171.22 KXH43976.1 - 7.5e-99 331.3 0.0 9.2e-99 331.0 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DAO PF01266.24 KXH43977.1 - 2.8e-30 106.1 0.0 3.3e-30 105.9 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXH43977.1 - 2.3e-07 31.0 0.0 9.3e-07 29.0 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KXH43977.1 - 0.00025 20.4 0.1 0.015 14.6 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXH43977.1 - 0.0017 17.6 0.0 1.4 8.1 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXH43977.1 - 0.0034 16.5 0.1 0.62 9.1 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain GIDA PF01134.22 KXH43977.1 - 0.0041 16.3 0.4 0.064 12.3 0.2 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_9 PF13454.6 KXH43977.1 - 0.013 15.5 0.0 0.92 9.5 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 KXH43977.1 - 0.022 14.0 0.0 0.21 10.8 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.14 KXH43977.1 - 0.025 13.3 0.1 1.6 7.3 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein Lycopene_cycl PF05834.12 KXH43977.1 - 0.047 12.7 0.2 3.6 6.5 0.1 2.4 2 0 0 2 2 2 0 Lycopene cyclase protein Thi4 PF01946.17 KXH43977.1 - 0.047 12.9 0.2 0.11 11.7 0.0 1.7 2 0 0 2 2 2 0 Thi4 family K_oxygenase PF13434.6 KXH43977.1 - 0.055 12.6 0.0 7.9 5.5 0.0 2.2 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Amino_oxidase PF01593.24 KXH43977.1 - 0.09 12.0 0.0 1.6 8.0 0.0 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase TrkA_N PF02254.18 KXH43977.1 - 0.12 12.6 0.0 0.38 11.0 0.0 1.9 2 0 0 2 2 2 0 TrkA-N domain Fungal_trans PF04082.18 KXH43978.1 - 8.5e-16 57.8 0.9 1.5e-15 57.0 0.9 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cucumopine_C PF18631.1 KXH43978.1 - 0.081 12.9 0.0 1.3 9.0 0.0 2.5 1 1 1 2 2 2 0 Cucumopine synthase C-terminal helical bundle domain Aa_trans PF01490.18 KXH43979.1 - 5.7e-41 140.6 27.6 6.5e-41 140.4 27.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Pro_racemase PF05544.11 KXH43980.1 - 1e-124 415.9 0.0 1.1e-124 415.7 0.0 1.0 1 0 0 1 1 1 1 Proline racemase PhzC-PhzF PF02567.16 KXH43980.1 - 0.00081 18.9 0.0 0.0016 18.0 0.0 1.4 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein OCD_Mu_crystall PF02423.15 KXH43981.1 - 1.6e-13 50.3 0.2 9.7e-12 44.4 0.2 2.7 1 1 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.20 KXH43981.1 - 2.3e-09 37.4 0.0 1.3e-06 28.5 0.0 3.1 2 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase GFO_IDH_MocA PF01408.22 KXH43981.1 - 0.066 14.0 0.0 0.16 12.8 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold p450 PF00067.22 KXH43982.1 - 3.5e-58 197.5 0.0 4.2e-58 197.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3687 PF12459.8 KXH43982.1 - 0.18 11.4 0.1 0.38 10.3 0.1 1.4 1 0 0 1 1 1 0 D-Ala-teichoic acid biosynthesis protein Fungal_trans PF04082.18 KXH43983.1 - 2.6e-09 36.5 0.2 4.8e-09 35.6 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH43983.1 - 0.29 11.3 3.8 0.47 10.6 3.8 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain ABC2_membrane PF01061.24 KXH43984.1 - 3.5e-77 258.5 61.9 2.2e-41 141.6 25.1 3.7 4 0 0 4 4 4 2 ABC-2 type transporter PDR_CDR PF06422.12 KXH43984.1 - 3.2e-35 119.9 2.1 3.3e-31 107.0 0.1 3.4 2 0 0 2 2 2 2 CDR ABC transporter ABC_tran PF00005.27 KXH43984.1 - 7.7e-35 120.4 0.0 2.8e-16 60.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_trans_N PF14510.6 KXH43984.1 - 4.1e-14 52.9 0.0 1.3e-13 51.3 0.0 1.9 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 KXH43984.1 - 3.9e-06 27.3 0.1 0.1 13.0 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain ABC2_membrane_3 PF12698.7 KXH43984.1 - 9e-06 25.0 11.9 9e-06 25.0 11.9 3.1 3 0 0 3 3 3 2 ABC-2 family transporter protein RsgA_GTPase PF03193.16 KXH43984.1 - 7.4e-05 22.7 0.1 0.01 15.8 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 KXH43984.1 - 0.00011 21.9 1.2 0.031 14.0 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_25 PF13481.6 KXH43984.1 - 0.00015 21.5 0.1 0.001 18.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 KXH43984.1 - 0.00026 20.5 0.0 0.033 13.6 0.0 3.1 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_33 PF13671.6 KXH43984.1 - 0.00096 19.3 1.0 0.065 13.4 0.0 3.1 4 0 0 4 4 3 1 AAA domain AAA_21 PF13304.6 KXH43984.1 - 0.0011 18.9 1.0 1.3 8.8 0.1 2.6 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 KXH43984.1 - 0.0044 17.6 0.1 0.054 14.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KXH43984.1 - 0.01 16.1 0.6 2.2 8.6 0.2 2.6 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 KXH43984.1 - 0.036 13.7 2.6 0.14 11.8 0.1 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Zeta_toxin PF06414.12 KXH43984.1 - 0.036 13.3 0.9 0.16 11.3 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin AAA_30 PF13604.6 KXH43984.1 - 0.048 13.4 0.7 2.8 7.6 0.0 2.7 3 0 0 3 3 2 0 AAA domain MMR_HSR1 PF01926.23 KXH43984.1 - 0.06 13.4 0.2 9.6 6.3 0.2 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_23 PF13476.6 KXH43984.1 - 0.068 13.7 0.0 0.14 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 KXH43984.1 - 0.12 11.4 0.2 2.7 7.0 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_17 PF13207.6 KXH43984.1 - 0.13 12.7 0.9 3.1 8.2 0.0 2.6 3 0 0 3 3 2 0 AAA domain AAA PF00004.29 KXH43984.1 - 0.21 12.0 0.1 20 5.6 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 KXH43984.1 - 0.34 10.8 4.3 6.8 6.6 0.2 2.9 3 0 0 3 3 3 0 NACHT domain PDR_assoc PF08370.11 KXH43984.1 - 0.45 10.3 11.4 1.2 8.9 0.7 3.7 3 0 0 3 3 3 0 Plant PDR ABC transporter associated Bac_luciferase PF00296.20 KXH43985.1 - 5.3e-68 229.7 0.0 6.6e-68 229.5 0.0 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase Zn_clus PF00172.18 KXH43987.1 - 0.023 14.8 0.2 0.023 14.8 0.2 1.6 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain PNTB_4TM PF12769.7 KXH43987.1 - 0.15 12.5 0.3 0.4 11.2 0.2 1.7 2 0 0 2 2 2 0 4TM region of pyridine nucleotide transhydrogenase, mitoch GFA PF04828.14 KXH43988.1 - 3.1e-20 72.3 3.3 7.9e-11 42.1 0.2 4.0 3 1 1 4 4 4 3 Glutathione-dependent formaldehyde-activating enzyme MFS_1 PF07690.16 KXH43989.1 - 4.4e-39 134.4 47.1 4.4e-39 134.4 47.1 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH43989.1 - 7.1e-10 38.3 2.6 7.1e-10 38.3 2.6 3.1 2 1 1 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 KXH43989.1 - 6.5e-09 34.7 17.1 1.3e-08 33.8 17.1 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF5056 PF16479.5 KXH43989.1 - 0.085 13.1 0.2 0.085 13.1 0.2 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF5056) OATP PF03137.20 KXH43989.1 - 2.6 6.2 12.7 0.012 13.9 2.7 2.2 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family FAD_binding_4 PF01565.23 KXH43990.1 - 9.2e-17 61.1 0.0 1.7e-16 60.3 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Cupin_1 PF00190.22 KXH43991.1 - 5.1e-05 22.9 0.0 9.7e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.11 KXH43991.1 - 5.8e-05 22.7 0.3 0.0001 21.9 0.3 1.4 1 0 0 1 1 1 1 Cupin domain ARD PF03079.14 KXH43991.1 - 0.0032 17.7 0.0 0.0045 17.2 0.0 1.2 1 0 0 1 1 1 1 ARD/ARD' family Cupin_6 PF12852.7 KXH43991.1 - 0.027 14.2 0.0 0.034 13.9 0.0 1.2 1 0 0 1 1 1 0 Cupin DUF829 PF05705.14 KXH43992.1 - 1.2e-49 169.3 0.0 1.4e-49 169.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) 4HBT_3 PF13622.6 KXH43993.1 - 3.4e-49 168.4 0.1 3.9e-49 168.2 0.1 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Ala_racemase_N PF01168.20 KXH43994.1 - 1.9e-27 96.4 0.1 2.4e-27 96.0 0.1 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain D-ser_dehydrat PF14031.6 KXH43994.1 - 5.6e-23 81.4 0.0 1.2e-22 80.4 0.0 1.6 1 0 0 1 1 1 1 Putative serine dehydratase domain GTP_CH_N PF12471.8 KXH43994.1 - 0.023 14.4 0.0 0.054 13.2 0.0 1.5 1 0 0 1 1 1 0 GTP cyclohydrolase N terminal RuvX PF03652.15 KXH43994.1 - 0.045 14.1 0.1 0.27 11.6 0.0 2.2 2 0 0 2 2 2 0 Holliday junction resolvase p450 PF00067.22 KXH43995.1 - 9.5e-48 163.1 0.0 1.2e-47 162.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 D-ser_dehydrat PF14031.6 KXH43996.1 - 1.9e-23 83.0 0.0 4e-23 81.9 0.0 1.6 1 0 0 1 1 1 1 Putative serine dehydratase domain Ala_racemase_N PF01168.20 KXH43996.1 - 1.2e-15 57.8 0.0 1.7e-15 57.3 0.0 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Fungal_trans_2 PF11951.8 KXH43997.1 - 6.8e-42 143.6 5.5 9.2e-42 143.2 5.5 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH43997.1 - 2.6e-07 30.7 12.9 4e-07 30.0 12.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DDDD PF10161.9 KXH44000.1 - 0.1 12.4 1.7 7.2 6.4 0.2 2.7 2 0 0 2 2 2 0 Putative mitochondrial precursor protein DUF2236 PF09995.9 KXH44001.1 - 4.2e-28 99.1 0.2 6.7e-28 98.4 0.2 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) CVNH PF08881.10 KXH44003.1 - 2.7e-09 37.6 2.3 4.4e-07 30.5 0.4 1.7 1 1 1 2 2 2 2 CVNH domain Inositol_P PF00459.25 KXH44004.1 - 4.4e-35 121.5 0.0 1.6e-34 119.7 0.0 1.8 1 1 0 1 1 1 1 Inositol monophosphatase family AA_permease PF00324.21 KXH44005.1 - 3.3e-95 319.5 34.3 3.7e-95 319.3 34.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KXH44005.1 - 1.1e-24 87.1 39.3 1.4e-24 86.8 39.3 1.0 1 0 0 1 1 1 1 Amino acid permease Myb_DNA-binding PF00249.31 KXH44044.1 - 0.014 15.5 0.1 0.032 14.4 0.1 1.7 1 1 0 1 1 1 0 Myb-like DNA-binding domain Septin PF00735.18 KXH44045.1 - 8.7e-33 113.8 0.0 2.3e-11 43.5 0.0 3.2 3 0 0 3 3 3 3 Septin AAA_16 PF13191.6 KXH44045.1 - 0.0095 16.3 0.1 0.041 14.3 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 KXH44045.1 - 0.011 16.3 0.1 0.034 14.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 KXH44045.1 - 0.07 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AT_hook PF02178.19 KXH44184.1 - 0.0078 16.0 5.0 0.033 14.0 5.0 2.2 1 0 0 1 1 1 1 AT hook motif Plasmodium_Vir PF05795.11 KXH44184.1 - 4.1 6.7 4.1 5.2 6.4 4.1 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein PQ-loop PF04193.14 KXH44185.1 - 7e-21 73.8 4.1 3.9e-11 42.5 1.0 2.5 2 0 0 2 2 2 2 PQ loop repeat CutC PF03932.14 KXH44185.1 - 0.13 11.7 0.1 1.9 7.9 0.0 2.0 2 0 0 2 2 2 0 CutC family SprT-like PF10263.9 KXH44188.1 - 4.1e-15 55.6 0.1 7.1e-15 54.8 0.1 1.4 1 0 0 1 1 1 1 SprT-like family SprT-like PF10263.9 KXH44189.1 - 0.052 13.4 0.2 0.19 11.6 0.1 2.2 2 1 0 2 2 2 0 SprT-like family Pou PF00157.17 KXH44190.1 - 0.026 14.5 0.0 0.5 10.4 0.0 2.6 3 0 0 3 3 3 0 Pou domain - N-terminal to homeobox domain HTH_31 PF13560.6 KXH44190.1 - 0.11 12.9 0.9 1.4 9.3 0.1 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain NnrU PF07298.11 KXH44192.1 - 0.094 12.2 7.1 0.75 9.3 1.0 2.5 2 1 0 2 2 2 0 NnrU protein HET PF06985.11 KXH44193.1 - 7.6e-23 81.5 0.0 6.2e-18 65.5 0.0 2.3 2 0 0 2 2 2 2 Heterokaryon incompatibility protein (HET) hnRNP_Q_AcD PF18360.1 KXH44193.1 - 0.017 15.1 0.1 7.3 6.6 0.1 2.5 2 0 0 2 2 2 0 Heterogeneous nuclear ribonucleoprotein Q acidic domain TRI5 PF06330.11 KXH44194.1 - 4.7e-12 45.5 0.0 6.4e-12 45.0 0.0 1.2 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) Frankia_peptide PF14407.6 KXH44195.1 - 0.0099 15.8 0.2 0.019 14.9 0.2 1.5 1 0 0 1 1 1 1 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. SprT-like PF10263.9 KXH44195.1 - 0.12 12.2 0.1 0.28 11.1 0.1 1.6 1 0 0 1 1 1 0 SprT-like family Gal4_dimer PF03902.13 KXH44195.1 - 0.16 12.1 0.0 0.37 11.0 0.0 1.5 1 0 0 1 1 1 0 Gal4-like dimerisation domain Pkinase PF00069.25 KXH44196.1 - 2.2e-58 197.7 0.0 2.9e-58 197.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXH44196.1 - 5.4e-28 98.0 0.0 8.2e-28 97.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXH44196.1 - 5.9e-07 29.1 0.0 8.7e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KXH44196.1 - 0.064 13.2 0.0 2.9 7.7 0.0 2.3 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 KXH44196.1 - 0.073 12.4 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family UQ_con PF00179.26 KXH44198.1 - 4.3e-47 159.3 0.0 5e-47 159.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KXH44198.1 - 8.8e-06 25.5 0.0 1.2e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KXH44198.1 - 0.011 16.0 0.0 0.012 15.9 0.0 1.3 1 0 0 1 1 1 0 RWD domain UEV PF05743.13 KXH44198.1 - 0.021 14.7 0.0 0.033 14.1 0.0 1.4 1 1 0 1 1 1 0 UEV domain Ribosomal_L31e PF01198.19 KXH44199.1 - 4e-39 132.7 0.3 5.6e-39 132.3 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L31e RGS PF00615.19 KXH44200.1 - 6.7e-12 45.7 0.0 3.7e-10 40.1 0.0 2.3 1 1 0 1 1 1 1 Regulator of G protein signaling domain RR_TM4-6 PF06459.12 KXH44200.1 - 0.16 11.7 0.4 0.27 11.0 0.4 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PCI PF01399.27 KXH44201.1 - 6.1e-07 29.9 0.0 1.3e-06 28.9 0.0 1.6 1 0 0 1 1 1 1 PCI domain CSN7a_helixI PF18392.1 KXH44201.1 - 0.019 14.9 0.0 0.038 13.9 0.0 1.5 1 0 0 1 1 1 0 COP9 signalosome complex subunit 7a helix I domain MIF4G_like PF09088.11 KXH44201.1 - 0.11 12.2 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 MIF4G like E1-E2_ATPase PF00122.20 KXH44202.1 - 4.2e-51 173.0 0.1 1.4e-50 171.3 0.1 1.9 1 0 0 1 1 1 1 E1-E2 ATPase HMA PF00403.26 KXH44202.1 - 1e-44 150.8 6.6 1.4e-11 44.6 0.1 4.5 4 0 0 4 4 4 4 Heavy-metal-associated domain Hydrolase PF00702.26 KXH44202.1 - 7.7e-38 130.9 2.1 7.7e-38 130.9 2.1 1.8 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KXH44202.1 - 6.5e-05 22.8 1.6 0.00037 20.3 0.3 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase CDCA PF18484.1 KXH44202.1 - 0.00073 19.5 4.4 0.67 9.8 0.0 3.6 3 1 0 4 4 4 2 Cadmium carbonic anhydrase repeat FAM70 PF14967.6 KXH44202.1 - 0.059 12.8 0.5 14 5.0 0.0 3.3 3 0 0 3 3 3 0 FAM70 protein HAD PF12710.7 KXH44202.1 - 0.082 13.3 0.0 0.2 12.0 0.0 1.7 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase RelB_N PF18506.1 KXH44202.1 - 9.3 6.1 9.8 63 3.5 0.1 4.1 4 0 0 4 4 4 0 RelB Antitoxin alpha helical domain DUF155 PF02582.14 KXH44203.1 - 1.1e-55 188.4 0.4 1.9e-55 187.7 0.1 1.5 2 0 0 2 2 2 1 Uncharacterised ACR, YagE family COG1723 ECSCR PF15820.5 KXH44203.1 - 0.087 12.7 0.3 0.25 11.2 0.1 1.8 2 0 0 2 2 2 0 Endothelial cell-specific chemotaxis regulator Insulin_TMD PF17870.1 KXH44203.1 - 0.14 12.3 0.6 0.25 11.5 0.6 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment zinc_ribbon_15 PF17032.5 KXH44205.1 - 0.00015 22.5 0.6 0.00021 22.0 0.6 1.2 1 0 0 1 1 1 1 zinc-ribbon family RNase_P_p30 PF01876.16 KXH44206.1 - 1.8e-56 191.0 0.0 2.9e-56 190.3 0.0 1.3 1 0 0 1 1 1 1 RNase P subunit p30 DUF1295 PF06966.12 KXH44208.1 - 1.2e-57 195.2 0.3 1.6e-57 194.7 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.16 KXH44208.1 - 9.4e-07 28.9 0.1 9.4e-07 28.9 0.1 2.8 2 1 1 3 3 3 1 3-oxo-5-alpha-steroid 4-dehydrogenase ICMT PF04140.14 KXH44208.1 - 0.00015 22.1 0.7 0.0005 20.4 0.0 2.3 2 1 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KXH44208.1 - 0.0014 19.0 1.6 0.0067 16.8 0.0 2.8 2 1 1 3 3 3 1 Phospholipid methyltransferase DUF1056 PF06341.11 KXH44208.1 - 2.8 8.3 0.0 2.8 8.3 0.0 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF1056) Glyco_hydro_61 PF03443.14 KXH44209.1 - 1.5e-66 224.3 0.2 1.9e-66 223.9 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Ank_2 PF12796.7 KXH44211.1 - 1.9e-16 60.4 0.0 4.4e-06 27.2 0.0 4.5 2 2 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXH44211.1 - 9.9e-11 42.0 0.2 0.0014 19.1 0.0 4.4 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXH44211.1 - 1.9e-07 31.2 0.1 0.0017 18.6 0.0 4.5 3 1 2 5 5 5 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXH44211.1 - 7.9e-06 25.8 4.2 3.6 8.5 0.0 6.5 7 0 0 7 7 7 2 Ankyrin repeat Ank PF00023.30 KXH44211.1 - 4.1e-05 23.8 1.6 8.3 7.0 0.1 5.1 4 1 0 4 4 4 2 Ankyrin repeat Pectinesterase PF01095.19 KXH44212.1 - 6.9e-51 172.7 7.8 8.4e-51 172.4 7.8 1.1 1 0 0 1 1 1 1 Pectinesterase DUF3762 PF12591.8 KXH44212.1 - 0.028 14.7 1.3 0.051 13.8 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3762) DUF3533 PF12051.8 KXH44213.1 - 3.7e-64 217.0 14.7 4.3e-64 216.8 14.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) MFS_1 PF07690.16 KXH44214.1 - 1.7e-19 69.9 40.2 1.7e-19 69.9 40.2 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH44214.1 - 0.00029 19.8 15.2 0.00029 19.8 15.2 3.2 2 2 1 3 3 3 1 Sugar (and other) transporter Peptidase_S8 PF00082.22 KXH44215.1 - 6.7e-43 147.1 0.7 1e-42 146.5 0.7 1.2 1 0 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 KXH44215.1 - 2.3e-07 31.5 0.0 4.1e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Fn3-like domain Gpi16 PF04113.14 KXH44216.1 - 9.8e-247 819.9 0.0 1.2e-246 819.6 0.0 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component LUC7 PF03194.15 KXH44217.1 - 1.6e-70 237.6 2.9 2e-70 237.4 2.9 1.0 1 0 0 1 1 1 1 LUC7 N_terminus DUF1241 PF06840.11 KXH44217.1 - 0.038 13.7 0.1 0.063 12.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1241) GRP PF07172.11 KXH44217.1 - 0.061 14.0 7.4 0.14 12.9 7.4 1.6 1 0 0 1 1 1 0 Glycine rich protein family MCPsignal PF00015.21 KXH44217.1 - 0.076 12.8 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Sec8_exocyst PF04048.14 KXH44217.1 - 0.11 12.3 0.4 0.2 11.5 0.1 1.6 1 1 1 2 2 2 0 Sec8 exocyst complex component specific domain SpecificRecomb PF10136.9 KXH44217.1 - 0.27 9.5 0.2 0.52 8.6 0.1 1.3 1 1 0 1 1 1 0 Site-specific recombinase TFIIA PF03153.13 KXH44218.1 - 0.0033 17.5 17.0 0.0044 17.1 17.0 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Nuc_deoxyri_tr2 PF15891.5 KXH44219.1 - 1.4e-36 125.1 0.0 1.9e-36 124.7 0.0 1.2 1 0 0 1 1 1 1 Nucleoside 2-deoxyribosyltransferase like Peptidase_M20 PF01546.28 KXH44221.1 - 4.9e-23 81.9 0.0 5.1e-22 78.6 0.0 2.4 2 1 0 2 2 2 1 Peptidase family M20/M25/M40 WD40 PF00400.32 KXH44221.1 - 4.3e-14 52.7 0.4 0.24 12.3 0.0 6.8 6 0 0 6 6 6 4 WD domain, G-beta repeat Invas_SpaK PF03519.14 KXH44221.1 - 0.03 14.4 0.2 0.94 9.6 0.0 2.7 3 0 0 3 3 3 0 Invasion protein B family Peptidase_M28 PF04389.17 KXH44221.1 - 0.031 14.0 0.0 0.066 12.9 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M28 M20_dimer PF07687.14 KXH44221.1 - 0.056 13.4 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Peptidase dimerisation domain Asparaginase_2 PF01112.18 KXH44222.1 - 2.6e-52 177.8 2.0 1.3e-28 99.9 0.2 4.0 3 2 0 3 3 3 3 Asparaginase Tim17 PF02466.19 KXH44223.1 - 3.1e-32 111.3 6.3 4e-32 110.9 6.3 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Acetyltransf_1 PF00583.25 KXH44224.1 - 2e-13 50.6 0.0 2.5e-13 50.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXH44224.1 - 9e-13 48.3 0.0 1.1e-12 48.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXH44224.1 - 4.3e-12 46.3 0.0 6.4e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXH44224.1 - 0.0028 17.6 0.0 0.0048 16.8 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 KXH44224.1 - 0.0052 16.9 0.0 0.0095 16.0 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.7 KXH44224.1 - 0.11 12.6 0.0 0.13 12.4 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain RicinB_lectin_2 PF14200.6 KXH44225.1 - 0.095 13.4 0.0 2 9.2 0.1 2.0 1 1 1 2 2 2 0 Ricin-type beta-trefoil lectin domain-like BTK PF00779.19 KXH44227.1 - 0.12 12.2 0.3 0.12 12.2 0.3 2.6 2 0 0 2 2 2 0 BTK motif Arylsulfotran_2 PF14269.6 KXH44228.1 - 7.5e-97 324.3 0.2 1.2e-96 323.7 0.2 1.3 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) DUF885 PF05960.11 KXH44228.1 - 6.7e-34 118.4 1.7 4e-33 115.9 1.8 2.1 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF885) Arylsulfotrans PF05935.11 KXH44228.1 - 8.4e-09 34.8 0.0 4e-08 32.6 0.0 1.9 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) DUF4253 PF14062.6 KXH44228.1 - 0.0039 17.3 0.0 0.012 15.8 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4253) DUF4286 PF14114.6 KXH44228.1 - 0.05 14.1 0.1 0.16 12.4 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4286) Fungal_trans PF04082.18 KXH44229.1 - 1.7e-22 79.8 0.0 3.3e-22 78.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH44229.1 - 9.3e-05 22.5 11.7 0.00017 21.6 11.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_88 PF07470.13 KXH44230.1 - 5.4e-10 38.9 0.4 1.2e-09 37.8 0.4 1.6 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 MFS_1 PF07690.16 KXH44231.1 - 7.4e-22 77.7 23.7 7.4e-22 77.7 23.7 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF4538 PF15061.6 KXH44231.1 - 0.27 11.0 1.9 4.1 7.2 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4538) DUF423 PF04241.15 KXH44231.1 - 5.3 7.3 7.6 27 5.1 1.9 3.1 1 1 1 2 2 2 0 Protein of unknown function (DUF423) Dabb PF07876.12 KXH44232.1 - 1.6e-14 54.3 0.1 2.4e-14 53.7 0.1 1.3 1 1 0 1 1 1 1 Stress responsive A/B Barrel Domain ABM PF03992.16 KXH44232.1 - 0.02 15.0 0.3 0.098 12.8 0.3 2.0 1 1 0 1 1 1 0 Antibiotic biosynthesis monooxygenase DUF3198 PF11433.8 KXH44232.1 - 0.11 12.3 0.1 0.2 11.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3198) adh_short_C2 PF13561.6 KXH44233.1 - 2e-57 194.4 5.8 1.1e-56 192.1 5.8 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXH44233.1 - 1.1e-40 139.2 3.5 1.4e-40 138.8 3.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXH44233.1 - 0.0057 16.6 0.6 0.0093 15.9 0.6 1.3 1 0 0 1 1 1 1 KR domain ILVD_EDD PF00920.21 KXH44234.1 - 9.1e-158 526.1 0.4 1e-157 525.9 0.4 1.0 1 0 0 1 1 1 1 Dehydratase family Fungal_trans PF04082.18 KXH44235.1 - 4.2e-25 88.3 0.4 7.5e-25 87.5 0.4 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ldh_2 PF02615.14 KXH44236.1 - 1.1e-124 415.9 0.7 1.3e-124 415.8 0.7 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase Ntox10 PF15520.6 KXH44237.1 - 0.004 17.0 0.0 0.0069 16.3 0.0 1.3 1 0 0 1 1 1 1 Novel toxin 10 PSI PF01437.25 KXH44237.1 - 0.089 13.3 8.7 2.1 8.9 4.3 2.9 2 0 0 2 2 2 0 Plexin repeat Methyltransf_23 PF13489.6 KXH44238.1 - 1.5e-11 44.4 0.0 2.7e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH44238.1 - 1.7e-08 35.0 0.0 6.5e-08 33.1 0.0 2.0 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH44238.1 - 1.3e-07 32.2 0.0 7.1e-06 26.6 0.0 2.4 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH44238.1 - 0.0017 19.1 0.0 0.0045 17.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH44238.1 - 0.011 15.5 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Git3 PF11710.8 KXH44239.1 - 1.2e-16 61.1 5.8 1.2e-16 61.1 5.8 1.9 2 1 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.21 KXH44239.1 - 3.1e-08 33.3 2.4 4.2e-08 32.8 2.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) GPR_Gpa2_C PF11970.8 KXH44239.1 - 1.8e-05 24.7 0.5 1.8e-05 24.7 0.5 2.0 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term His_Phos_2 PF00328.22 KXH44240.1 - 0.003 17.0 1.2 1.2 8.4 0.0 2.9 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) Tail_spike_N PF18668.1 KXH44240.1 - 0.024 14.5 0.2 0.076 12.9 0.2 1.9 1 0 0 1 1 1 0 Tail spike TSP1/Gp66 receptor binding N-terminal domain PDGLE PF13190.6 KXH44240.1 - 0.044 13.7 0.2 0.12 12.3 0.2 1.8 1 0 0 1 1 1 0 PDGLE domain adh_short_C2 PF13561.6 KXH44241.1 - 2.1e-39 135.5 0.7 3.3e-39 134.9 0.7 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXH44241.1 - 1.9e-32 112.3 0.3 2.6e-32 111.9 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXH44241.1 - 2.9e-10 40.3 0.2 3e-08 33.8 0.1 2.1 2 0 0 2 2 2 2 KR domain Polysacc_synt_2 PF02719.15 KXH44241.1 - 0.0034 16.6 0.0 0.0049 16.0 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KXH44241.1 - 0.04 13.4 0.0 0.3 10.5 0.0 2.0 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Methyltransf_23 PF13489.6 KXH44242.1 - 4.6e-23 81.9 0.0 7.1e-23 81.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH44242.1 - 8.4e-11 42.4 0.0 1.7e-10 41.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH44242.1 - 1.6e-09 37.7 0.0 7.8e-09 35.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH44242.1 - 1e-06 29.3 0.0 1.8e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH44242.1 - 9.9e-06 26.2 0.0 3.4e-05 24.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXH44242.1 - 0.00061 19.4 0.0 0.0045 16.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase small domain FtsJ PF01728.19 KXH44242.1 - 0.0061 16.7 0.0 0.009 16.1 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_4 PF02390.17 KXH44242.1 - 0.015 14.8 0.0 0.12 11.8 0.0 2.1 2 0 0 2 2 2 0 Putative methyltransferase Ubie_methyltran PF01209.18 KXH44242.1 - 0.017 14.5 0.0 0.66 9.3 0.0 2.6 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 KXH44242.1 - 0.024 13.9 0.0 0.05 12.9 0.0 1.5 1 0 0 1 1 1 0 O-methyltransferase domain PrmA PF06325.13 KXH44242.1 - 0.047 13.1 0.0 0.072 12.5 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.9 KXH44242.1 - 0.048 13.4 0.0 0.077 12.7 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase PCMT PF01135.19 KXH44242.1 - 0.08 12.7 0.0 0.71 9.6 0.0 2.1 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 KXH44243.1 - 0.00031 20.6 0.0 0.00038 20.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXH44244.1 - 7e-17 61.7 0.0 1.1e-16 61.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH44244.1 - 1.7e-11 44.7 0.0 3.9e-11 43.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH44244.1 - 3.8e-10 39.8 0.0 4.8e-09 36.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH44244.1 - 6.1e-09 36.5 0.0 3.5e-08 34.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH44244.1 - 3e-08 34.2 0.0 4.9e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXH44244.1 - 0.0014 18.2 0.0 0.039 13.5 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_4 PF02390.17 KXH44244.1 - 0.0082 15.6 0.0 0.043 13.3 0.0 1.9 2 0 0 2 2 2 1 Putative methyltransferase FtsJ PF01728.19 KXH44244.1 - 0.015 15.4 0.0 0.024 14.8 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase DUF4357 PF14267.6 KXH44244.1 - 0.068 13.1 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4357) Ubie_methyltran PF01209.18 KXH44244.1 - 0.077 12.3 0.0 0.79 9.0 0.0 2.1 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family GidB PF02527.15 KXH44244.1 - 0.087 12.1 0.0 0.86 8.9 0.0 2.2 1 1 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_16 PF10294.9 KXH44244.1 - 0.12 12.0 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase PrmA PF06325.13 KXH44244.1 - 0.2 11.0 0.0 0.31 10.4 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DUF1772 PF08592.11 KXH44245.1 - 1.8e-07 31.5 5.8 1.4e-06 28.7 5.8 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF1772) MscS_TM PF12794.7 KXH44245.1 - 3.4 6.4 6.0 0.82 8.5 2.5 1.7 2 1 0 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 Per1 PF04080.13 KXH44246.1 - 3.3e-107 358.0 6.1 4.1e-107 357.7 6.1 1.1 1 0 0 1 1 1 1 Per1-like family DUF4401 PF14351.6 KXH44246.1 - 0.19 11.0 9.8 0.091 12.1 7.4 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4401) DUF3681 PF12442.8 KXH44246.1 - 2 8.9 7.7 1.2 9.7 3.8 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3681) Ank_2 PF12796.7 KXH44247.1 - 7e-64 212.4 4.9 1.5e-15 57.6 0.0 4.8 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXH44247.1 - 3e-40 136.1 2.9 6.5e-09 36.2 0.0 8.2 3 1 4 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXH44247.1 - 1.9e-35 116.9 1.3 0.0017 18.7 0.0 10.5 10 1 0 10 10 10 7 Ankyrin repeat Ank PF00023.30 KXH44247.1 - 2.8e-35 119.2 15.0 3.9e-05 23.9 0.1 9.9 10 1 0 10 10 10 7 Ankyrin repeat Ank_5 PF13857.6 KXH44247.1 - 3.8e-34 116.3 9.1 2e-08 34.4 0.1 7.2 5 1 2 7 7 7 5 Ankyrin repeats (many copies) RVP PF00077.20 KXH44247.1 - 0.026 14.8 0.3 3.3 8.1 0.0 2.8 1 1 1 2 2 2 0 Retroviral aspartyl protease DUF2384 PF09722.10 KXH44247.1 - 0.084 12.9 0.2 1.9 8.6 0.1 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2384) PhoD PF09423.10 KXH44248.1 - 7e-06 25.3 2.3 0.00055 19.1 0.2 2.4 3 0 0 3 3 3 2 PhoD-like phosphatase Aldedh PF00171.22 KXH44249.1 - 2.7e-106 355.9 0.0 3.4e-106 355.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family HLH PF00010.26 KXH44250.1 - 2e-12 46.9 0.2 3.6e-12 46.0 0.2 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain SUIM_assoc PF16619.5 KXH44250.1 - 0.0089 16.1 3.1 0.0089 16.1 3.1 3.2 3 0 0 3 3 3 1 Unstructured region C-term to UIM in Ataxin3 Macoilin PF09726.9 KXH44250.1 - 7.2 5.0 12.5 0.92 8.0 6.7 1.9 2 0 0 2 2 2 0 Macoilin family Ank_2 PF12796.7 KXH44252.1 - 1e-39 135.0 3.8 2.4e-12 47.2 0.0 9.5 7 2 2 9 9 9 6 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXH44252.1 - 8.6e-28 93.3 5.0 0.01 16.3 0.0 12.4 12 0 0 12 12 12 6 Ankyrin repeat Ank_4 PF13637.6 KXH44252.1 - 1.1e-25 89.6 6.1 5e-05 23.8 0.0 10.0 10 1 1 11 11 11 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXH44252.1 - 6.5e-24 83.7 14.0 0.0051 17.1 0.0 10.7 9 1 1 10 10 10 7 Ankyrin repeats (many copies) Ank PF00023.30 KXH44252.1 - 3.7e-20 71.4 14.4 0.0033 17.8 0.0 11.8 13 0 0 13 13 13 5 Ankyrin repeat YfcL PF08891.11 KXH44252.1 - 0.11 12.9 0.0 0.38 11.1 0.0 2.0 1 0 0 1 1 1 0 YfcL protein VIT1 PF01988.19 KXH44252.1 - 0.13 12.1 0.0 0.49 10.2 0.0 2.0 1 0 0 1 1 1 0 VIT family Rad60-SLD PF11976.8 KXH44253.1 - 1.8e-21 75.7 0.1 2.6e-20 72.0 0.1 2.3 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KXH44253.1 - 1.7e-07 30.9 0.0 3.2e-06 26.8 0.0 2.3 2 0 0 2 2 2 1 Ubiquitin family TmoB PF06234.12 KXH44253.1 - 0.003 17.6 0.0 0.0063 16.6 0.0 1.6 1 0 0 1 1 1 1 Toluene-4-monooxygenase system protein B (TmoB) Ribosomal_60s PF00428.19 KXH44253.1 - 0.17 12.5 0.4 0.17 12.5 0.4 3.6 3 0 0 3 3 3 0 60s Acidic ribosomal protein LSM PF01423.22 KXH44254.1 - 1.2e-21 76.1 0.1 1.4e-21 75.9 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KXH44254.1 - 7.1e-05 22.9 0.1 8.7e-05 22.6 0.1 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 KXH44254.1 - 0.00047 20.2 0.1 0.00057 19.9 0.1 1.1 1 0 0 1 1 1 1 Scd6-like Sm domain Hfq PF17209.3 KXH44254.1 - 0.1 12.2 0.1 0.14 11.8 0.1 1.2 1 0 0 1 1 1 0 Hfq protein Methyltransf_11 PF08241.12 KXH44255.1 - 1.4e-11 44.9 0.0 2.7e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH44255.1 - 2.6e-10 40.9 0.0 4.8e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH44255.1 - 8.4e-06 26.5 0.0 1.8e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXH44255.1 - 4e-05 23.5 0.0 5.7e-05 23.0 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXH44255.1 - 0.00021 20.7 0.0 0.00029 20.2 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family DREV PF05219.12 KXH44255.1 - 0.00093 18.4 0.0 0.0021 17.2 0.0 1.5 1 1 0 1 1 1 1 DREV methyltransferase Methyltransf_31 PF13847.6 KXH44255.1 - 0.0069 16.2 0.0 0.014 15.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXH44255.1 - 0.0093 15.5 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain RrnaAD PF00398.20 KXH44255.1 - 0.011 14.8 0.0 0.016 14.2 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase FtsJ PF01728.19 KXH44255.1 - 0.1 12.7 0.0 0.16 12.1 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase Imm70 PF15601.6 KXH44255.1 - 0.13 11.8 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 Immunity protein 70 PCMT PF01135.19 KXH44255.1 - 0.16 11.7 0.0 0.35 10.6 0.0 1.5 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Cys_Met_Meta_PP PF01053.20 KXH44258.1 - 5.1e-57 193.1 0.0 1.1e-56 192.0 0.0 1.5 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KXH44258.1 - 0.12 11.5 0.0 0.25 10.5 0.0 1.4 1 1 0 1 1 1 0 Aminotransferase class I and II Aminotran_5 PF00266.19 KXH44258.1 - 0.19 10.7 0.0 0.3 10.0 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V Terpene_synth_C PF03936.16 KXH44259.1 - 3.5e-05 23.3 0.6 0.00025 20.5 0.7 2.1 1 1 1 2 2 2 1 Terpene synthase family, metal binding domain Borrelia_orfA PF02414.15 KXH44259.1 - 0.11 12.1 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Borrelia ORF-A Polysacc_deac_1 PF01522.21 KXH44260.1 - 4.2e-20 71.9 0.0 9.8e-20 70.7 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide deacetylase Polysacc_deac_2 PF04748.13 KXH44260.1 - 0.014 14.6 0.0 0.025 13.8 0.0 1.5 1 0 0 1 1 1 0 Divergent polysaccharide deacetylase DUF2026 PF09641.10 KXH44262.1 - 0.039 13.6 0.1 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2026) Skp1 PF01466.19 KXH44262.1 - 0.044 13.9 0.3 0.088 12.9 0.3 1.4 1 0 0 1 1 1 0 Skp1 family, dimerisation domain WD40 PF00400.32 KXH44264.1 - 2.5e-14 53.4 8.1 0.0095 16.8 0.1 5.6 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXH44264.1 - 7.9e-07 29.3 0.6 0.0024 18.1 0.2 4.0 2 1 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KXH44264.1 - 1.2e-06 27.6 0.9 2e-05 23.4 0.1 2.6 2 1 1 3 3 3 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 KXH44264.1 - 0.026 13.3 0.0 6.3 5.4 0.0 2.8 2 1 1 3 3 3 0 Nup133 N terminal like HA2 PF04408.23 KXH44265.1 - 2.8e-22 79.1 0.0 2.8e-22 79.1 0.0 3.7 4 0 0 4 4 4 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KXH44265.1 - 1.4e-19 70.2 0.0 5.4e-19 68.3 0.0 2.0 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KXH44265.1 - 1.7e-14 54.1 0.0 3.8e-14 53.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KXH44265.1 - 6.5e-08 32.5 0.0 1.2e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF2075 PF09848.9 KXH44265.1 - 6e-05 22.5 0.0 0.00011 21.6 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 KXH44265.1 - 0.00012 22.4 0.1 0.00031 21.0 0.1 1.7 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 KXH44265.1 - 0.0015 17.7 0.0 0.003 16.6 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.6 KXH44265.1 - 0.0023 18.3 0.0 0.0051 17.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 KXH44265.1 - 0.0025 17.5 0.1 0.0054 16.4 0.1 1.6 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain ResIII PF04851.15 KXH44265.1 - 0.0025 17.8 0.0 0.94 9.5 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 KXH44265.1 - 0.0028 17.4 0.0 0.0068 16.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 KXH44265.1 - 0.0064 15.9 0.0 0.014 14.8 0.0 1.5 1 0 0 1 1 1 1 KaiC Flavi_DEAD PF07652.14 KXH44265.1 - 0.022 14.7 0.0 0.041 13.8 0.0 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain GAD PF02938.14 KXH44265.1 - 0.043 14.0 0.0 0.13 12.6 0.0 1.7 1 0 0 1 1 1 0 GAD domain ABC_tran PF00005.27 KXH44265.1 - 0.094 13.2 0.3 0.29 11.6 0.0 2.1 2 0 0 2 2 1 0 ABC transporter TrwB_AAD_bind PF10412.9 KXH44265.1 - 0.097 11.6 0.0 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_14 PF13173.6 KXH44265.1 - 0.11 12.6 0.2 0.61 10.1 0.2 2.2 1 1 0 1 1 1 0 AAA domain Myosin_head PF00063.21 KXH44265.1 - 0.11 10.7 0.0 0.17 10.0 0.0 1.2 1 0 0 1 1 1 0 Myosin head (motor domain) Microtub_bd PF16796.5 KXH44265.1 - 0.12 12.3 0.0 0.81 9.6 0.0 2.3 2 0 0 2 2 2 0 Microtubule binding Acylphosphatase PF00708.18 KXH44266.1 - 5.1e-07 30.0 0.1 6e-07 29.8 0.1 1.0 1 0 0 1 1 1 1 Acylphosphatase HATPase_c PF02518.26 KXH44359.1 - 1.1e-23 83.9 0.1 2.3e-23 82.8 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KXH44359.1 - 9.3e-21 74.1 0.0 1.9e-20 73.1 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 KXH44359.1 - 7e-07 29.2 1.5 9.7e-07 28.7 0.1 2.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.7 KXH44359.1 - 7.2e-07 29.4 0.1 2.8e-05 24.3 0.1 3.0 2 1 1 3 3 3 1 PAS domain PAS_4 PF08448.10 KXH44359.1 - 1.4e-06 28.5 0.0 0.0046 17.2 0.0 2.9 2 0 0 2 2 2 2 PAS fold GAF_2 PF13185.6 KXH44359.1 - 3.8e-06 27.2 0.0 0.0052 17.1 0.0 2.7 2 0 0 2 2 2 2 GAF domain PAS PF00989.25 KXH44359.1 - 4.3e-05 23.5 0.1 0.00041 20.3 0.0 2.4 2 0 0 2 2 2 1 PAS fold PAS_3 PF08447.12 KXH44359.1 - 0.0019 18.5 0.0 0.0053 17.0 0.0 1.7 1 0 0 1 1 1 1 PAS fold GAF_3 PF13492.6 KXH44359.1 - 0.0088 16.4 0.0 0.03 14.7 0.0 2.0 1 0 0 1 1 1 1 GAF domain PAS_8 PF13188.7 KXH44359.1 - 0.018 15.0 0.0 0.17 11.9 0.0 2.5 2 0 0 2 2 2 0 PAS domain DEAD PF00270.29 KXH44361.1 - 8.2e-25 87.6 0.0 2.1e-23 83.0 0.0 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXH44361.1 - 8.4e-24 84.1 0.0 2.4e-23 82.6 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXH44361.1 - 0.00014 21.9 1.1 0.00024 21.1 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CENP-B_dimeris PF09026.10 KXH44361.1 - 0.007 16.7 10.9 0.021 15.2 10.9 1.8 1 0 0 1 1 1 1 Centromere protein B dimerisation domain SDA1 PF05285.12 KXH44361.1 - 0.0091 15.5 8.8 0.0091 15.5 8.8 2.9 3 0 0 3 3 3 1 SDA1 DNA_pol_phi PF04931.13 KXH44361.1 - 0.026 12.7 18.2 0.028 12.6 16.3 1.9 2 0 0 2 2 2 0 DNA polymerase phi RRN3 PF05327.11 KXH44361.1 - 0.16 10.5 5.0 0.3 9.6 5.0 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 TRAP_alpha PF03896.16 KXH44361.1 - 3.3 6.8 15.8 0.052 12.8 8.1 1.9 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit TSA PF03249.13 KXH44361.1 - 5.1 5.8 7.3 0.16 10.7 0.6 1.8 2 0 0 2 2 2 0 Type specific antigen PH_6 PF15406.6 KXH44362.1 - 2.5e-47 159.8 5.3 2.5e-47 159.8 5.3 3.2 3 0 0 3 3 3 1 Pleckstrin homology domain PH PF00169.29 KXH44362.1 - 4.1e-05 24.0 0.1 0.00014 22.3 0.0 2.1 2 1 0 2 2 2 1 PH domain tRNA-synt_2 PF00152.20 KXH44364.1 - 9.6e-61 205.6 0.0 1.9e-60 204.6 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KXH44364.1 - 2.4e-09 37.1 0.0 4.5e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KXH44364.1 - 0.00014 21.4 0.0 0.052 13.0 0.0 2.4 2 1 0 2 2 2 2 tRNA synthetases class II core domain (F) Mcm10 PF09332.11 KXH44364.1 - 0.16 11.4 1.3 0.36 10.2 0.9 1.7 2 0 0 2 2 2 0 Mcm10 replication factor zf-Tim10_DDP PF02953.15 KXH44365.1 - 6.8e-19 67.3 1.8 8.9e-19 66.9 1.8 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF2897 PF11446.8 KXH44367.1 - 0.091 12.7 0.0 0.26 11.2 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) CLTH PF10607.9 KXH44368.1 - 4.8e-31 107.6 0.0 1.4e-30 106.1 0.0 1.7 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.6 KXH44368.1 - 8.3e-10 38.5 2.6 1.5e-09 37.7 2.6 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KXH44368.1 - 7.3e-07 29.1 2.1 1.3e-06 28.3 2.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 KXH44368.1 - 5.8e-05 23.4 2.8 9.9e-05 22.6 2.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KXH44368.1 - 5.8e-05 22.9 2.1 9.7e-05 22.2 2.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KXH44368.1 - 0.00011 22.0 2.5 0.0002 21.1 2.5 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KXH44368.1 - 0.00039 20.2 3.5 0.00072 19.4 3.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXH44368.1 - 0.00061 19.6 3.9 0.0012 18.7 3.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.12 KXH44368.1 - 0.0021 17.5 0.1 0.0033 16.8 0.1 1.3 1 0 0 1 1 1 1 Rtf2 RING-finger zf-C3HC4_4 PF15227.6 KXH44368.1 - 0.0039 17.3 3.4 0.0088 16.2 3.4 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 KXH44368.1 - 0.096 12.5 2.0 0.17 11.7 2.0 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C2HC5 PF06221.13 KXH44368.1 - 0.11 12.4 0.3 0.24 11.4 0.3 1.4 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type XhlA PF10779.9 KXH44369.1 - 0.016 15.4 0.1 0.045 14.0 0.1 1.8 1 0 0 1 1 1 0 Haemolysin XhlA Spc7 PF08317.11 KXH44369.1 - 0.094 11.6 3.9 0.18 10.6 3.9 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF1664 PF07889.12 KXH44369.1 - 0.12 12.4 2.4 0.31 11.1 1.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) HMMR_N PF15905.5 KXH44369.1 - 0.17 11.3 5.2 0.32 10.4 5.2 1.3 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Laminin_II PF06009.12 KXH44369.1 - 0.3 11.1 3.4 3.8 7.5 0.7 2.8 1 1 2 3 3 3 0 Laminin Domain II AAA_13 PF13166.6 KXH44369.1 - 0.94 8.0 3.7 1.3 7.5 3.7 1.1 1 0 0 1 1 1 0 AAA domain ATG16 PF08614.11 KXH44369.1 - 3.4 7.9 9.4 5 7.3 6.1 2.3 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Tropomyosin_1 PF12718.7 KXH44369.1 - 6.1 7.0 10.4 0.15 12.3 1.3 2.6 2 1 0 2 2 2 0 Tropomyosin like WD40 PF00400.32 KXH44370.1 - 2.7e-13 50.2 20.8 3e-05 24.7 0.2 11.0 12 0 0 12 12 12 2 WD domain, G-beta repeat MCR_alpha PF02249.17 KXH44370.1 - 0.047 14.1 0.1 0.21 12.0 0.1 2.1 1 0 0 1 1 1 0 Methyl-coenzyme M reductase alpha subunit, C-terminal domain SUR7 PF06687.12 KXH44371.1 - 1.1e-36 126.4 11.8 1.8e-36 125.8 11.8 1.3 1 0 0 1 1 1 1 SUR7/PalI family TMEM43 PF07787.12 KXH44371.1 - 0.034 13.5 0.4 0.062 12.7 0.4 1.4 1 0 0 1 1 1 0 Transmembrane protein 43 Metallophos PF00149.28 KXH44372.1 - 1e-33 117.6 0.0 1.5e-33 117.0 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KXH44372.1 - 5.1e-17 62.1 0.0 9.3e-17 61.2 0.0 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Dus PF01207.17 KXH44373.1 - 4.7e-37 127.7 0.0 6.2e-28 97.8 0.0 2.6 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) zf_CCCH_4 PF18345.1 KXH44373.1 - 0.01 15.9 8.6 0.99 9.6 1.1 3.3 3 0 0 3 3 3 0 Zinc finger domain zf-CCCH PF00642.24 KXH44373.1 - 5.1 7.1 10.3 1.3 9.1 0.1 2.8 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Gag_p10 PF02337.17 KXH44375.1 - 0.086 12.8 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Retroviral GAG p10 protein CBP PF12192.8 KXH44376.1 - 4.9e-09 36.3 5.3 4.9e-09 36.3 5.3 1.8 1 1 1 2 2 2 1 Fungal calcium binding protein Bap31 PF05529.12 KXH44377.1 - 3.2e-49 166.2 9.6 4.4e-49 165.8 9.6 1.2 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region Bap31_Bap29_C PF18035.1 KXH44377.1 - 8.9e-15 54.4 7.2 1.4e-14 53.8 7.2 1.4 1 0 0 1 1 1 1 Bap31/Bap29 cytoplasmic coiled-coil domain TolA_bind_tri PF16331.5 KXH44377.1 - 0.0017 18.4 0.3 0.004 17.2 0.3 1.6 1 0 0 1 1 1 1 TolA binding protein trimerisation TMF_DNA_bd PF12329.8 KXH44377.1 - 0.012 15.6 3.5 0.021 14.8 3.5 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DUF2956 PF11169.8 KXH44377.1 - 0.026 14.7 4.4 0.044 14.0 4.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) Csm1_N PF18504.1 KXH44377.1 - 0.049 14.0 0.4 0.085 13.2 0.4 1.5 1 0 0 1 1 1 0 Csm1 N-terminal domain DUF192 PF02643.15 KXH44377.1 - 0.062 13.4 0.1 0.11 12.7 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized ACR, COG1430 DUF1079 PF06435.11 KXH44377.1 - 0.18 12.1 0.6 14 6.1 0.1 2.3 2 0 0 2 2 2 0 Repeat of unknown function (DUF1079) DivIC PF04977.15 KXH44377.1 - 0.34 10.7 5.1 0.6 9.9 0.8 2.8 2 1 1 3 3 3 0 Septum formation initiator CAMSAP_CC1 PF17095.5 KXH44377.1 - 0.53 10.2 6.4 0.67 9.8 3.7 2.2 1 1 1 2 2 2 0 Spectrin-binding region of Ca2+-Calmodulin Peroxin-13_N PF04088.13 KXH44378.1 - 4.2e-51 173.0 0.0 5.7e-51 172.6 0.0 1.2 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_2 PF07653.17 KXH44378.1 - 1.1e-08 34.7 0.0 2.1e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KXH44378.1 - 1.1e-06 28.2 0.0 2.1e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KXH44378.1 - 1.3e-06 28.1 0.0 2.5e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.11 KXH44378.1 - 0.036 14.4 0.0 0.072 13.4 0.0 1.5 1 0 0 1 1 1 0 Bacterial SH3 domain MFS_1 PF07690.16 KXH44404.1 - 7.4e-36 123.8 24.6 2.8e-35 121.9 25.6 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily LapA_dom PF06305.11 KXH44404.1 - 1 9.2 4.2 5.7 6.8 0.2 3.5 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain NADH-u_ox-rdase PF10785.9 KXH44404.1 - 1.3 9.8 4.3 0.87 10.3 1.0 2.4 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit DUF3147 PF11345.8 KXH44406.1 - 0.49 10.8 3.5 0.15 12.4 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3147) Fungal_trans_2 PF11951.8 KXH44407.1 - 2.3e-34 118.9 13.1 3.9e-32 111.5 13.1 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH44407.1 - 3.7e-07 30.2 6.0 6.1e-07 29.5 6.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Alk_phosphatase PF00245.20 KXH44408.1 - 2.1e-75 254.3 0.0 2.8e-75 253.9 0.0 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Sulfatase PF00884.23 KXH44408.1 - 2.8e-05 23.7 0.0 5e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KXH44408.1 - 0.00048 19.8 0.1 0.00079 19.1 0.1 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 KXH44408.1 - 0.02 14.2 1.3 0.046 13.1 0.2 2.0 3 0 0 3 3 3 0 Metalloenzyme superfamily DUF229 PF02995.17 KXH44408.1 - 0.038 12.6 0.2 0.055 12.1 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) DUF2135 PF09906.9 KXH44408.1 - 0.13 12.6 0.9 0.22 11.8 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2135) SET PF00856.28 KXH44409.1 - 3.3e-13 50.4 0.0 4e-12 46.8 0.0 2.5 2 1 0 2 2 2 1 SET domain TPR_11 PF13414.6 KXH44409.1 - 1.2e-05 24.9 1.2 0.49 10.1 0.2 3.8 4 0 0 4 4 4 2 TPR repeat Sds3 PF08598.11 KXH44409.1 - 0.023 14.7 0.0 0.034 14.1 0.0 1.2 1 0 0 1 1 1 0 Sds3-like SAF PF08666.12 KXH44409.1 - 0.041 14.5 0.1 23 5.7 0.0 3.0 3 0 0 3 3 3 0 SAF domain TPR_2 PF07719.17 KXH44409.1 - 5.5 7.4 11.0 3.3 8.0 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat zf-C2H2_4 PF13894.6 KXH44410.1 - 1.2e-17 63.0 20.7 0.0092 16.7 0.4 6.6 6 0 0 6 6 6 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KXH44410.1 - 6.5e-14 51.8 25.5 4.3e-07 30.0 2.1 5.4 6 0 0 6 6 5 3 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 KXH44410.1 - 3.2e-13 49.3 25.1 0.004 17.5 0.7 6.7 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 KXH44410.1 - 7.5e-11 41.8 13.6 0.0099 15.9 0.9 5.5 5 0 0 5 5 5 4 C2H2-type zinc finger zf-met PF12874.7 KXH44410.1 - 8.5e-11 41.9 25.5 0.00053 20.3 0.4 5.4 7 0 0 7 7 6 3 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KXH44410.1 - 2.6e-09 37.3 21.7 0.0058 16.9 2.1 5.1 2 2 3 5 5 5 3 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.6 KXH44410.1 - 0.00014 22.1 28.4 0.74 10.4 0.1 6.8 6 0 0 6 6 6 2 Zinc-finger double domain zf_ZIC PF18366.1 KXH44410.1 - 0.0012 18.9 9.0 2.2 8.5 0.1 4.7 5 0 0 5 5 5 2 Zic proteins zinc finger domain Rad50_zn_hook PF04423.14 KXH44410.1 - 0.012 15.4 3.4 2.7 7.9 0.0 3.5 3 0 0 3 3 3 0 Rad50 zinc hook motif AKAP95 PF04988.12 KXH44410.1 - 0.027 14.7 9.6 1.8 8.8 0.5 3.9 3 1 1 4 4 4 0 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_11 PF16622.5 KXH44410.1 - 0.028 14.2 10.3 0.37 10.6 0.5 4.9 5 0 0 5 5 5 0 zinc-finger C2H2-type zf-Di19 PF05605.12 KXH44410.1 - 0.032 14.5 0.0 0.032 14.5 0.0 4.5 4 2 0 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding zf-C2HC_2 PF13913.6 KXH44410.1 - 0.034 14.1 9.3 3.4 7.7 0.0 4.5 4 0 0 4 4 4 0 zinc-finger of a C2HC-type Zn-ribbon_8 PF09723.10 KXH44410.1 - 0.78 9.9 23.0 16 5.7 0.3 5.5 4 1 1 5 5 5 0 Zinc ribbon domain zf-C2H2_9 PF16293.5 KXH44410.1 - 7.2 6.5 11.8 4.1 7.3 0.2 4.4 4 2 1 5 5 5 0 C2H2 type zinc-finger (1 copy) NmrA PF05368.13 KXH44411.1 - 4.4e-20 72.2 0.0 6.8e-20 71.6 0.0 1.3 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXH44411.1 - 1.4e-14 54.4 0.0 2.9e-14 53.4 0.0 1.5 2 0 0 2 2 2 1 NAD(P)H-binding DXP_reductoisom PF02670.16 KXH44411.1 - 0.00057 20.6 0.1 0.043 14.5 0.0 2.4 2 1 0 2 2 2 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase Semialdhyde_dh PF01118.24 KXH44411.1 - 0.0033 17.9 0.1 0.02 15.3 0.1 2.1 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.21 KXH44411.1 - 0.016 14.7 0.0 0.039 13.4 0.0 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family CFEM PF05730.11 KXH44413.1 - 5.2e-14 52.1 11.1 8e-14 51.5 11.1 1.3 1 0 0 1 1 1 1 CFEM domain DUF1418 PF07214.12 KXH44413.1 - 0.27 11.1 4.9 0.15 12.0 1.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1418) PAP_PilO PF06864.12 KXH44415.1 - 0.061 12.1 0.0 0.095 11.5 0.0 1.2 1 0 0 1 1 1 0 Pilin accessory protein (PilO) VCBS PF13517.6 KXH44417.1 - 3.4e-33 114.0 32.6 1.5e-11 44.7 3.3 7.8 7 1 1 8 8 8 7 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Lipase_GDSL_2 PF13472.6 KXH44417.1 - 2e-11 44.6 0.6 4.8e-11 43.4 0.6 1.7 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family TcdB_toxin_midN PF12256.8 KXH44417.1 - 1.9e-09 37.2 5.1 0.18 11.2 0.0 5.6 4 2 2 6 6 6 3 Insecticide toxin TcdB middle/N-terminal region Dockerin_1 PF00404.18 KXH44417.1 - 6.9e-05 23.0 6.1 1.9 8.7 0.1 4.7 4 0 0 4 4 4 2 Dockerin type I domain Lipase_GDSL PF00657.22 KXH44417.1 - 0.00029 20.9 0.0 0.00063 19.8 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase PliI PF16743.5 KXH44417.1 - 0.00051 19.8 0.8 0.13 12.0 0.0 3.8 3 1 1 4 4 4 1 Periplasmic lysozyme inhibitor of I-type lysozyme FG-GAP PF01839.23 KXH44417.1 - 0.0007 19.7 24.6 0.0061 16.7 0.2 5.4 5 0 0 5 5 5 3 FG-GAP repeat Lactamase_B_3 PF13483.6 KXH44418.1 - 3e-05 24.0 0.3 5e-05 23.2 0.3 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 KXH44418.1 - 0.00027 20.5 0.2 0.00065 19.3 0.2 1.9 2 1 0 2 2 2 1 Beta-lactamase superfamily domain p450 PF00067.22 KXH44419.1 - 1.7e-64 218.3 0.0 2.1e-64 218.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.18 KXH44420.1 - 5e-21 74.9 0.1 7e-21 74.4 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH44420.1 - 7.1e-08 32.4 7.9 1.3e-07 31.6 7.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf_Rg PF17915.1 KXH44421.1 - 0.029 13.8 2.7 0.34 10.3 0.5 2.6 1 1 1 2 2 2 0 Reverse gyrase zinc finger F-box-like PF12937.7 KXH44422.1 - 0.00085 19.2 0.8 0.0039 17.0 0.1 2.3 2 0 0 2 2 2 1 F-box-like Glyco_hydro_106 PF17132.4 KXH44423.1 - 7.9e-21 74.0 0.0 2.3e-20 72.5 0.0 1.7 1 1 0 1 1 1 1 alpha-L-rhamnosidase Glyco_hydro_35 PF01301.19 KXH44424.1 - 4.4e-78 263.1 0.0 7.5e-78 262.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.9 KXH44424.1 - 2.3e-57 193.7 0.1 3.7e-57 193.1 0.1 1.3 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.6 KXH44424.1 - 5.8e-55 184.8 4.7 5.2e-33 114.0 0.1 2.6 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.6 KXH44424.1 - 4.8e-18 64.5 0.0 9.5e-18 63.5 0.0 1.5 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 GRDP-like PF07173.12 KXH44425.1 - 3e-07 31.2 5.3 0.0016 19.1 0.5 3.5 3 1 1 4 4 4 3 Glycine-rich domain-containing protein-like Peptidase_S9 PF00326.21 KXH44426.1 - 0.00034 20.1 0.0 0.00061 19.3 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase_phd PF10503.9 KXH44426.1 - 0.0015 18.1 0.0 0.012 15.2 0.0 2.4 2 1 0 2 2 2 1 Esterase PHB depolymerase Peptidase_S15 PF02129.18 KXH44426.1 - 0.059 12.9 0.0 0.086 12.4 0.0 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) DUF354 PF04007.12 KXH44426.1 - 0.23 10.5 0.0 0.34 9.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF354) ADH_zinc_N_2 PF13602.6 KXH44427.1 - 1.1e-26 94.5 0.0 1.8e-26 93.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KXH44427.1 - 1.4e-23 83.3 0.0 5.6e-23 81.3 0.0 2.0 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXH44427.1 - 0.0008 19.3 0.0 0.15 11.9 0.0 2.6 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 KXH44427.1 - 0.0054 16.3 0.0 0.0097 15.4 0.0 1.4 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus Methyltransf_25 PF13649.6 KXH44427.1 - 0.034 14.8 0.0 0.084 13.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 KXH44427.1 - 0.065 13.9 0.0 0.16 12.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Tannase PF07519.11 KXH44428.1 - 3e-94 316.6 0.7 3.5e-94 316.4 0.7 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_S9 PF00326.21 KXH44428.1 - 1.3e-05 24.8 0.0 0.0065 16.0 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KXH44428.1 - 0.00026 20.3 0.0 0.041 13.1 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KXH44428.1 - 0.0024 17.6 0.1 0.0045 16.7 0.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 KXH44428.1 - 0.038 13.6 0.0 0.075 12.7 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Zn_clus PF00172.18 KXH44429.1 - 5.8e-08 32.7 10.3 9.1e-08 32.1 10.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Lys-AminoMut_A PF09043.11 KXH44429.1 - 0.16 10.4 0.1 0.66 8.4 0.0 1.7 2 0 0 2 2 2 0 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit PseudoU_synth_1 PF01416.20 KXH44430.1 - 9.5e-12 45.3 0.0 7.8e-10 39.2 0.0 2.9 3 0 0 3 3 3 1 tRNA pseudouridine synthase DUF2344 PF10105.9 KXH44430.1 - 0.026 14.4 1.2 0.088 12.6 0.0 2.2 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2344) Med22 PF06179.12 KXH44431.1 - 1.5e-20 73.3 0.1 1.9e-20 73.0 0.1 1.1 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex APH PF01636.23 KXH44432.1 - 9.3e-07 29.0 0.0 2.1e-06 27.8 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KXH44432.1 - 0.022 14.4 0.0 0.039 13.5 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase dTDP_sugar_isom PF00908.17 KXH44432.1 - 0.11 12.2 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 dTDP-4-dehydrorhamnose 3,5-epimerase Pkinase PF00069.25 KXH44433.1 - 2.3e-13 50.1 0.0 4.3e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain DUF1616 PF07760.11 KXH44433.1 - 0.11 11.9 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1616) AA_permease_2 PF13520.6 KXH44434.1 - 1.5e-25 89.9 21.3 5e-24 84.9 21.3 2.6 1 1 0 1 1 1 1 Amino acid permease zf-CHY PF05495.12 KXH44434.1 - 0.039 14.5 0.0 0.083 13.4 0.0 1.5 1 0 0 1 1 1 0 CHY zinc finger TMEM190 PF15431.6 KXH44434.1 - 0.16 12.1 0.3 1 9.5 0.0 2.4 3 0 0 3 3 3 0 Transmembrane protein 190 Abhydrolase_9_N PF15420.6 KXH44434.1 - 6.1 6.8 8.5 0.31 11.0 0.3 2.7 3 1 1 4 4 4 0 Alpha/beta-hydrolase family N-terminus fn3_5 PF06280.12 KXH44435.1 - 0.015 16.0 0.6 0.056 14.1 0.1 2.3 2 0 0 2 2 2 0 Fn3-like domain CbtA PF09490.10 KXH44436.1 - 0.056 13.2 0.9 1.7 8.4 0.0 2.3 2 0 0 2 2 2 0 Probable cobalt transporter subunit (CbtA) Abhydrolase_9_N PF15420.6 KXH44436.1 - 0.062 13.3 0.4 0.11 12.5 0.4 1.3 1 0 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus Trp_DMAT PF11991.8 KXH44438.1 - 3.8e-111 372.0 0.0 5e-111 371.6 0.0 1.1 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase bZIP_1 PF00170.21 KXH44440.1 - 9.6e-08 32.0 16.4 2.1e-07 31.0 16.4 1.5 1 0 0 1 1 1 1 bZIP transcription factor PAP1 PF08601.10 KXH44440.1 - 9e-06 25.7 17.3 0.00012 22.0 0.0 2.4 1 1 1 2 2 2 1 Transcription factor PAP1 V_ATPase_I PF01496.19 KXH44440.1 - 0.0019 16.2 3.5 0.0023 15.9 3.5 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family SHE3 PF17078.5 KXH44440.1 - 0.0056 16.4 10.2 0.025 14.3 8.9 2.0 1 1 1 2 2 2 1 SWI5-dependent HO expression protein 3 TFIIA PF03153.13 KXH44440.1 - 0.03 14.3 11.8 0.033 14.2 11.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ADIP PF11559.8 KXH44440.1 - 0.036 14.2 12.0 0.065 13.3 12.0 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DivIC PF04977.15 KXH44440.1 - 0.057 13.2 4.7 0.15 11.8 4.7 1.7 1 0 0 1 1 1 0 Septum formation initiator DUF641 PF04859.12 KXH44440.1 - 0.063 13.6 6.8 0.1 12.9 6.8 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) bZIP_Maf PF03131.17 KXH44440.1 - 0.073 13.6 16.1 0.054 14.0 14.5 1.7 1 1 0 1 1 1 0 bZIP Maf transcription factor FlaC_arch PF05377.11 KXH44440.1 - 0.4 11.1 2.2 0.86 10.0 2.2 1.6 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) bZIP_2 PF07716.15 KXH44440.1 - 0.43 10.7 19.5 1.5 9.0 17.9 2.2 1 1 1 2 2 2 0 Basic region leucine zipper GvpL_GvpF PF06386.11 KXH44440.1 - 0.71 9.8 8.6 1.1 9.2 8.6 1.2 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF YabA PF06156.13 KXH44440.1 - 1.3 9.7 5.6 0.86 10.3 3.4 1.7 1 1 1 2 2 2 0 Initiation control protein YabA UPF0242 PF06785.11 KXH44440.1 - 3.2 7.8 8.2 4.8 7.3 8.2 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Peptidase_M28 PF04389.17 KXH44458.1 - 4.3e-37 127.7 0.0 7.7e-37 126.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KXH44458.1 - 0.0099 15.6 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Med11 PF10280.9 KXH44459.1 - 7.2e-49 165.8 0.1 8.9e-49 165.5 0.1 1.1 1 0 0 1 1 1 1 Mediator complex protein Mst1_SARAH PF11629.8 KXH44459.1 - 0.03 14.4 1.1 1.4 9.1 0.1 2.7 3 0 0 3 3 3 0 C terminal SARAH domain of Mst1 GPS2_interact PF15784.5 KXH44459.1 - 0.036 14.5 0.3 0.1 13.0 0.3 1.8 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Med21 PF11221.8 KXH44459.1 - 0.28 11.4 2.9 0.26 11.5 1.1 1.7 1 1 1 2 2 2 0 Subunit 21 of Mediator complex DEC-1_N PF04625.13 KXH44459.1 - 1.6 7.6 7.8 1.4 7.9 6.7 1.3 1 1 0 1 1 1 0 DEC-1 protein, N-terminal region WD40 PF00400.32 KXH44460.1 - 3.9e-40 135.1 25.0 8.3e-08 32.8 0.3 7.0 6 1 0 6 6 6 6 WD domain, G-beta repeat TFIID_NTD2 PF04494.15 KXH44460.1 - 2e-39 134.8 1.5 2.9e-39 134.2 1.5 1.2 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain ANAPC4_WD40 PF12894.7 KXH44460.1 - 4.7e-10 39.6 1.1 0.034 14.5 0.1 5.1 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KXH44460.1 - 4.6e-05 23.4 0.2 0.014 15.3 0.0 3.3 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.11 KXH44460.1 - 0.00023 20.1 0.1 1.2 7.8 0.0 3.9 2 2 0 3 3 3 1 Nup133 N terminal like Nup160 PF11715.8 KXH44460.1 - 0.00024 19.9 1.0 1.2 7.6 0.1 3.2 2 1 0 3 3 3 2 Nucleoporin Nup120/160 RAB3GAP2_N PF14655.6 KXH44460.1 - 0.00048 19.5 0.0 1.7 7.9 0.0 2.9 2 1 1 3 3 3 2 Rab3 GTPase-activating protein regulatory subunit N-terminus LisH PF08513.11 KXH44460.1 - 0.012 15.6 0.0 0.027 14.4 0.0 1.6 1 0 0 1 1 1 0 LisH Nbas_N PF15492.6 KXH44460.1 - 0.049 13.0 0.3 1.1 8.5 0.3 2.3 1 1 0 1 1 1 0 Neuroblastoma-amplified sequence, N terminal AsnC_trans_reg PF01037.21 KXH44460.1 - 0.089 12.8 0.0 0.34 10.9 0.0 2.0 1 0 0 1 1 1 0 Lrp/AsnC ligand binding domain Vps5 PF09325.10 KXH44461.1 - 4.1e-88 294.9 6.3 5.7e-88 294.4 6.3 1.2 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 KXH44461.1 - 3.3e-24 85.1 0.1 6.9e-24 84.0 0.0 1.6 2 0 0 2 2 2 1 PX domain BAR_2 PF10455.9 KXH44461.1 - 0.0005 19.3 2.3 0.001 18.3 2.3 1.6 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR_3 PF16746.5 KXH44461.1 - 0.0017 18.1 7.1 0.015 15.0 3.3 2.3 1 1 1 2 2 2 1 BAR domain of APPL family BAR_3_WASP_bdg PF10456.9 KXH44461.1 - 0.0042 16.6 0.8 0.04 13.4 0.8 2.1 1 1 0 1 1 1 1 WASP-binding domain of Sorting nexin protein DUF713 PF05218.14 KXH44461.1 - 0.17 11.6 6.0 0.14 11.9 1.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF713) DUF3450 PF11932.8 KXH44461.1 - 1.8 7.8 9.0 0.2 10.9 4.6 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) BAR PF03114.18 KXH44461.1 - 2.2 7.8 9.6 5.6 6.5 9.6 1.7 1 1 0 1 1 1 0 BAR domain Ribosomal_L31 PF01197.18 KXH44462.1 - 0.00014 22.0 0.0 0.00026 21.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L31 Glyco_hydro_16 PF00722.21 KXH44532.1 - 1.1e-16 60.9 0.3 3e-16 59.4 0.3 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.15 KXH44532.1 - 6.9e-06 24.7 1.9 0.033 12.6 0.8 2.1 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) DUF2401 PF10287.9 KXH44532.1 - 0.00017 21.2 0.0 0.00031 20.4 0.0 1.4 1 0 0 1 1 1 1 Putative TOS1-like glycosyl hydrolase (DUF2401) TFB6 PF17110.5 KXH44533.1 - 2.7e-67 225.8 0.0 3.6e-67 225.4 0.0 1.2 1 0 0 1 1 1 1 Subunit 11 of the general transcription factor TFIIH Tom6 PF17112.5 KXH44534.1 - 0.1 12.1 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom6, fungal DUF1996 PF09362.10 KXH44535.1 - 3e-79 266.3 0.1 5e-79 265.6 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) WSC PF01822.19 KXH44535.1 - 1.7e-20 73.0 9.3 1.7e-20 73.0 9.3 2.5 2 0 0 2 2 2 1 WSC domain MARVEL PF01284.23 KXH44537.1 - 0.0012 18.9 12.6 0.0012 18.9 12.6 2.1 1 1 1 2 2 2 2 Membrane-associating domain VIT1 PF01988.19 KXH44537.1 - 1.4 8.8 5.9 0.93 9.3 4.6 1.4 1 1 0 1 1 1 0 VIT family Y_phosphatase3 PF13350.6 KXH44538.1 - 1.4e-61 208.5 0.0 1.6e-61 208.3 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 KXH44538.1 - 0.00042 20.0 0.0 0.00059 19.5 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.13 KXH44538.1 - 0.0041 16.7 0.0 0.0069 16.0 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family Myotub-related PF06602.14 KXH44538.1 - 0.15 10.9 0.0 0.23 10.3 0.0 1.2 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain DSPc PF00782.20 KXH44538.1 - 0.17 11.7 0.0 0.52 10.1 0.0 1.8 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 KXH44538.1 - 0.2 11.8 0.0 0.36 10.9 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate Bot1p PF12298.8 KXH44539.1 - 1.8e-46 158.5 6.4 2.7e-46 157.9 6.4 1.3 1 0 0 1 1 1 1 Eukaryotic mitochondrial regulator protein Response_reg PF00072.24 KXH44540.1 - 2.4e-20 72.8 0.0 4.1e-14 52.7 0.0 2.4 2 0 0 2 2 2 2 Response regulator receiver domain DUF2052 PF09747.9 KXH44541.1 - 7e-32 111.2 16.1 7.4e-16 58.9 11.5 2.1 1 1 1 2 2 2 2 Coiled-coil domain containing protein (DUF2052) Glyco_hydro_43 PF04616.14 KXH44542.1 - 1.1e-31 110.2 5.0 2.6e-30 105.7 5.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 DUF4216 PF13952.6 KXH44542.1 - 0.078 13.4 0.7 0.16 12.4 0.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4216) Lipase_3 PF01764.25 KXH44543.1 - 2.4e-13 50.2 0.0 4.7e-12 46.0 0.0 2.3 1 1 0 1 1 1 1 Lipase (class 3) Acetyltransf_1 PF00583.25 KXH44545.1 - 2.5e-11 43.8 0.1 3.3e-11 43.4 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXH44545.1 - 7.8e-08 32.6 0.2 1.3e-07 31.9 0.2 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KXH44545.1 - 2e-06 27.8 0.1 2.7e-06 27.3 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain AstA PF04958.12 KXH44545.1 - 0.012 14.2 0.0 0.018 13.6 0.0 1.2 1 0 0 1 1 1 0 Arginine N-succinyltransferase beta subunit DUF1100 PF06500.11 KXH44546.1 - 3.7e-13 49.1 0.0 4.6e-13 48.8 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Peptidase_S9 PF00326.21 KXH44546.1 - 3.9e-06 26.5 0.0 7.3e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 KXH44546.1 - 1.4e-05 24.8 0.1 2.5e-05 24.0 0.1 1.4 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Esterase PF00756.20 KXH44546.1 - 5.3e-05 23.0 0.0 0.00054 19.7 0.0 2.2 1 1 0 1 1 1 1 Putative esterase Esterase_phd PF10503.9 KXH44546.1 - 0.0014 18.2 0.1 0.0054 16.3 0.0 2.0 3 0 0 3 3 3 1 Esterase PHB depolymerase Abhydrolase_6 PF12697.7 KXH44546.1 - 0.017 15.7 2.4 0.02 15.5 1.3 1.6 1 1 1 2 2 2 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXH44546.1 - 0.037 13.3 0.0 0.4 9.9 0.0 2.1 1 1 0 2 2 2 0 Serine aminopeptidase, S33 adh_short PF00106.25 KXH44547.1 - 3e-53 180.2 0.5 3.7e-53 179.9 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXH44547.1 - 9e-51 172.7 0.1 1.1e-50 172.3 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH44547.1 - 6.9e-14 52.2 0.8 1.6e-13 51.0 0.8 1.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KXH44547.1 - 1.4e-07 31.2 0.1 1.9e-07 30.8 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KXH44547.1 - 0.0038 16.4 0.3 0.011 14.9 0.1 1.7 2 0 0 2 2 2 1 RmlD substrate binding domain NmrA PF05368.13 KXH44547.1 - 0.0069 16.0 2.8 0.2 11.2 0.9 2.9 2 1 0 3 3 3 1 NmrA-like family DUF1815 PF08844.10 KXH44547.1 - 0.0097 15.9 0.0 0.018 15.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1815) GDP_Man_Dehyd PF16363.5 KXH44547.1 - 0.022 14.2 0.1 0.044 13.2 0.0 1.5 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Lambda_tail_I PF06805.12 KXH44547.1 - 0.053 13.9 0.0 11 6.5 0.0 2.5 2 0 0 2 2 2 0 Bacteriophage lambda tail assembly protein I ADH_N PF08240.12 KXH44548.1 - 3.8e-27 94.3 0.6 3.8e-27 94.3 0.6 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXH44548.1 - 2.1e-14 53.6 0.6 4.3e-14 52.6 0.6 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KXH44548.1 - 2.4e-06 27.2 0.0 0.033 13.7 0.0 2.6 2 1 0 2 2 2 2 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 KXH44548.1 - 0.0027 17.0 1.2 0.0027 17.0 1.2 1.8 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 KXH44548.1 - 0.012 15.2 0.3 0.034 13.7 0.1 1.8 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain HI0933_like PF03486.14 KXH44548.1 - 0.013 14.2 0.3 0.021 13.5 0.3 1.3 1 0 0 1 1 1 0 HI0933-like protein Aldo_ket_red PF00248.21 KXH44549.1 - 1.8e-46 158.7 0.1 2.4e-44 151.7 0.1 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family YflT PF11181.8 KXH44549.1 - 0.031 14.8 0.1 0.33 11.5 0.0 2.5 3 0 0 3 3 3 0 Heat induced stress protein YflT SNARE PF05739.19 KXH44550.1 - 4e-13 49.1 0.1 4e-13 49.1 0.1 1.8 2 0 0 2 2 2 1 SNARE domain Syntaxin-5_N PF11416.8 KXH44550.1 - 2.2e-09 36.3 0.3 6e-09 34.9 0.3 1.8 1 0 0 1 1 1 1 Syntaxin-5 N-terminal, Sly1p-binding domain KxDL PF10241.9 KXH44550.1 - 0.0067 16.7 4.2 1.5 9.1 0.1 3.6 4 0 0 4 4 4 2 Uncharacterized conserved protein Prominin PF05478.11 KXH44550.1 - 0.022 12.8 1.3 1.6 6.6 0.0 2.2 2 0 0 2 2 2 0 Prominin Syntaxin-18_N PF10496.9 KXH44550.1 - 0.035 14.4 2.2 0.2 11.9 0.1 2.5 2 0 0 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus Baculo_PEP_C PF04513.12 KXH44550.1 - 0.053 13.6 5.3 5.1 7.1 0.4 3.2 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Syntaxin PF00804.25 KXH44550.1 - 0.068 12.8 5.8 0.17 11.5 0.2 2.8 2 1 1 3 3 3 0 Syntaxin Raftlin PF15250.6 KXH44550.1 - 0.068 11.9 1.4 0.081 11.7 0.4 1.6 2 0 0 2 2 2 0 Raftlin DUF4407 PF14362.6 KXH44550.1 - 0.87 8.9 9.5 47 3.2 9.5 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) SF-assemblin PF06705.11 KXH44550.1 - 1.8 7.9 6.9 0.17 11.2 0.6 2.2 3 0 0 3 3 3 0 SF-assemblin/beta giardin NPV_P10 PF05531.12 KXH44550.1 - 2.7 8.5 5.6 15 6.2 0.1 3.4 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Muted PF14942.6 KXH44550.1 - 4.1 7.7 6.7 2.8 8.3 1.0 2.6 2 1 0 2 2 2 0 Organelle biogenesis, Muted-like protein TRP PF06011.12 KXH44553.1 - 3.4e-107 358.8 18.7 5.6e-107 358.1 18.7 1.3 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 KXH44553.1 - 8.9e-38 129.8 0.1 1.4e-37 129.2 0.1 1.3 1 0 0 1 1 1 1 ML-like domain ATP-sulfurylase PF01747.17 KXH44554.1 - 2.1e-87 292.0 0.2 3.1e-87 291.5 0.2 1.2 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.20 KXH44554.1 - 1.9e-57 193.6 0.0 2.9e-57 193.0 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.6 KXH44554.1 - 2.8e-54 183.1 0.0 4.5e-54 182.4 0.0 1.3 1 0 0 1 1 1 1 PUA-like domain TT_ORF2 PF02957.15 KXH44555.1 - 1.1 10.2 0.0 1.1 10.2 0.0 3.6 4 0 0 4 4 4 0 TT viral ORF2 betaPIX_CC PF16523.5 KXH44556.1 - 0.034 14.0 0.3 0.092 12.6 0.3 1.7 1 0 0 1 1 1 0 betaPIX coiled coil SRA1 PF07304.11 KXH44556.1 - 0.23 11.2 3.4 0.71 9.7 0.1 3.0 2 0 0 2 2 2 0 Steroid receptor RNA activator (SRA1) Fzo_mitofusin PF04799.13 KXH44556.1 - 0.51 9.9 7.3 0.8 9.2 1.8 2.3 1 1 1 2 2 2 0 fzo-like conserved region IBN_N PF03810.19 KXH44558.1 - 5.4e-10 39.0 4.7 0.00088 19.1 0.0 4.7 4 0 0 4 4 4 2 Importin-beta N-terminal domain Cse1 PF08506.10 KXH44558.1 - 9.2e-09 34.6 0.4 5.6e-08 32.0 0.0 2.4 2 1 1 3 3 3 1 Cse1 Xpo1 PF08389.12 KXH44558.1 - 1.2e-05 25.4 2.6 0.00013 22.1 0.1 3.6 4 0 0 4 4 4 1 Exportin 1-like protein HEAT_2 PF13646.6 KXH44558.1 - 0.0072 16.7 3.0 0.043 14.2 0.1 3.4 4 0 0 4 4 4 1 HEAT repeats GRIP PF01465.20 KXH44558.1 - 0.011 15.6 0.0 0.06 13.3 0.0 2.4 1 0 0 1 1 1 0 GRIP domain Metal_resist PF13801.6 KXH44558.1 - 8.7 6.6 9.9 1.1 9.4 4.4 2.4 3 0 0 3 3 3 0 Heavy-metal resistance Pkinase PF00069.25 KXH44562.1 - 8.5e-52 176.1 0.0 2.2e-51 174.7 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXH44562.1 - 5.9e-20 71.6 0.0 2.6e-19 69.5 0.0 2.0 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KXH44562.1 - 0.02 14.2 0.3 6 6.1 0.1 2.4 2 0 0 2 2 2 0 Kinase-like Chitin_synth_2 PF03142.15 KXH44563.1 - 1.2e-291 968.0 0.2 1.2e-291 968.0 0.2 1.4 2 0 0 2 2 2 1 Chitin synthase Glyco_trans_2_3 PF13632.6 KXH44563.1 - 1.5e-13 51.2 6.2 5.5e-13 49.3 6.2 2.0 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KXH44563.1 - 1.2e-11 44.9 0.0 7.9e-11 42.3 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 KXH44563.1 - 0.00011 21.7 0.0 0.0045 16.5 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 21 Cyt-b5 PF00173.28 KXH44563.1 - 0.0036 17.4 0.1 1.7 8.9 0.0 2.9 2 1 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glycos_transf_2 PF00535.26 KXH44563.1 - 0.01 15.6 0.0 0.043 13.6 0.0 2.0 2 0 0 2 2 2 0 Glycosyl transferase family 2 Sel1 PF08238.12 KXH44564.1 - 4.6e-39 132.0 30.7 3e-05 24.6 0.1 7.5 7 0 0 7 7 7 7 Sel1 repeat DUF3328 PF11807.8 KXH44565.1 - 1.8e-15 57.4 4.4 5e-13 49.3 0.1 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF3328) DUF3328 PF11807.8 KXH44566.1 - 3.7e-13 49.8 0.0 5.6e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) MFS_2 PF13347.6 KXH44567.1 - 1e-11 44.1 4.8 1e-11 44.1 4.8 2.2 2 0 0 2 2 2 1 MFS/sugar transport protein MFS_1_like PF12832.7 KXH44567.1 - 0.00021 20.3 0.0 0.00063 18.7 0.0 1.9 1 1 0 1 1 1 1 MFS_1 like family AMP-binding PF00501.28 KXH44569.1 - 5.6e-22 77.9 0.0 7.7e-22 77.5 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme DUF2309 PF10070.9 KXH44569.1 - 0.17 10.2 0.0 0.25 9.6 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2309) APH PF01636.23 KXH44570.1 - 5.4e-08 33.1 0.0 7.5e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 KXH44570.1 - 0.087 12.1 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase PhyH PF05721.13 KXH44571.1 - 1.3e-18 68.0 0.1 2e-18 67.4 0.1 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) p450 PF00067.22 KXH44574.1 - 2e-65 221.4 0.0 2.4e-65 221.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FSH1 PF03959.13 KXH44575.1 - 1e-32 113.5 0.0 1.4e-32 113.1 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 KXH44575.1 - 0.00082 19.2 0.1 0.0021 17.9 0.1 1.7 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 KXH44575.1 - 0.022 15.4 0.9 0.045 14.3 0.3 1.6 1 1 1 2 2 2 0 Alpha/beta hydrolase family ADH_N PF08240.12 KXH44576.1 - 2.9e-09 36.8 0.2 1.1e-08 34.9 0.2 2.0 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXH44576.1 - 5.4e-07 29.7 0.0 1.1e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF3328 PF11807.8 KXH44577.1 - 2e-18 67.0 3.1 2e-18 67.0 3.1 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3328) PS-DH PF14765.6 KXH44578.1 - 3.9e-50 170.8 0.0 8.3e-50 169.7 0.0 1.6 1 0 0 1 1 1 1 Polyketide synthase dehydratase Condensation PF00668.20 KXH44578.1 - 2.3e-49 168.3 0.0 4.1e-49 167.5 0.0 1.4 1 0 0 1 1 1 1 Condensation domain KR PF08659.10 KXH44578.1 - 1.3e-48 165.3 0.0 3.2e-48 164.0 0.0 1.7 1 0 0 1 1 1 1 KR domain ketoacyl-synt PF00109.26 KXH44578.1 - 5.3e-45 154.0 0.0 2.4e-38 132.2 0.0 2.9 1 1 1 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 KXH44578.1 - 1.7e-33 116.5 0.2 1.4e-31 110.2 0.2 2.4 1 1 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KXH44578.1 - 1.8e-30 105.4 0.0 4.2e-30 104.2 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 KXH44578.1 - 2.3e-19 70.0 0.0 7.7e-19 68.3 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 KXH44578.1 - 3.2e-15 56.5 0.0 8.3e-15 55.2 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_23 PF13489.6 KXH44578.1 - 1.1e-14 54.6 0.0 2.8e-14 53.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH44578.1 - 4e-12 46.7 0.0 1.8e-11 44.6 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH44578.1 - 1.4e-10 41.2 0.0 3.5e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH44578.1 - 2.9e-10 40.7 0.0 1.2e-09 38.7 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain adh_short PF00106.25 KXH44578.1 - 2.5e-08 33.6 0.0 1e-07 31.6 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase PP-binding PF00550.25 KXH44578.1 - 2.3e-06 27.9 0.0 6.8e-06 26.3 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Ubie_methyltran PF01209.18 KXH44578.1 - 0.00091 18.6 0.0 0.0018 17.6 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.9 KXH44578.1 - 0.065 13.0 0.0 0.2 11.4 0.0 1.8 1 0 0 1 1 1 0 Lysine methyltransferase NodS PF05401.11 KXH44578.1 - 0.096 12.3 0.0 0.28 10.8 0.0 1.7 1 0 0 1 1 1 0 Nodulation protein S (NodS) Pkinase PF00069.25 KXH44579.1 - 1.5e-65 221.2 0.0 2.1e-65 220.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXH44579.1 - 3e-42 144.7 0.0 4.3e-42 144.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXH44579.1 - 1.7e-05 24.3 0.0 2.8e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like POLO_box PF00659.18 KXH44579.1 - 2.4e-05 24.4 0.0 0.0044 17.2 0.0 2.8 2 0 0 2 2 2 1 POLO box duplicated region Kdo PF06293.14 KXH44579.1 - 0.0029 17.0 0.0 0.0059 16.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KXH44579.1 - 0.043 12.6 0.1 0.043 12.6 0.1 1.6 2 0 0 2 2 2 0 Fungal protein kinase TFIIA PF03153.13 KXH44579.1 - 5.5 6.9 9.6 12 5.8 9.6 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit OPA3 PF07047.12 KXH44580.1 - 1.7e-43 147.4 9.4 1.7e-43 147.4 9.4 1.9 1 1 1 2 2 2 1 Optic atrophy 3 protein (OPA3) PDE6_gamma PF04868.12 KXH44580.1 - 0.0062 16.7 0.0 0.018 15.2 0.0 1.8 1 0 0 1 1 1 1 Retinal cGMP phosphodiesterase, gamma subunit RAP1 PF07218.11 KXH44580.1 - 0.0093 14.3 5.7 0.011 14.1 5.7 1.2 1 0 0 1 1 1 1 Rhoptry-associated protein 1 (RAP-1) Macoilin PF09726.9 KXH44580.1 - 0.032 12.8 8.3 0.049 12.2 8.3 1.3 1 0 0 1 1 1 0 Macoilin family Inhibitor_I53 PF11714.8 KXH44580.1 - 0.036 14.2 1.4 0.11 12.7 0.1 2.4 2 0 0 2 2 2 0 Thrombin inhibitor Madanin SPX PF03105.19 KXH44580.1 - 0.09 12.7 15.8 0.16 11.9 15.7 1.3 1 1 0 1 1 1 0 SPX domain CAF-1_p150 PF11600.8 KXH44580.1 - 0.096 12.4 20.1 0.44 10.2 5.9 2.3 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Ribosomal_L12 PF00542.19 KXH44580.1 - 0.63 10.4 11.9 0.93 9.9 10.4 2.0 2 0 0 2 2 2 0 Ribosomal protein L7/L12 C-terminal domain VSG_B PF13206.6 KXH44580.1 - 0.89 8.7 11.1 6.1 6.0 11.1 1.9 1 1 0 1 1 1 0 Trypanosomal VSG domain PAP1 PF08601.10 KXH44580.1 - 0.94 9.1 9.5 1.5 8.5 9.5 1.3 1 0 0 1 1 1 0 Transcription factor PAP1 SSP160 PF06933.11 KXH44580.1 - 1.1 7.3 12.0 1.5 7.0 12.0 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Nop25 PF09805.9 KXH44580.1 - 1.6 9.2 15.5 0.3 11.6 4.4 2.2 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) Herpes_capsid PF06112.11 KXH44580.1 - 1.7 8.7 12.9 3.2 7.8 12.9 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein ADIP PF11559.8 KXH44580.1 - 1.9 8.6 16.7 0.64 10.1 5.9 2.2 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding FmiP_Thoc5 PF09766.9 KXH44580.1 - 1.9 7.7 13.5 0.1 11.9 5.8 2.0 2 0 0 2 2 2 0 Fms-interacting protein/Thoc5 LegC3_N PF18654.1 KXH44580.1 - 2.4 7.3 13.8 1.4 8.1 3.4 2.7 2 1 1 3 3 3 0 LegC3 N-terminal coiled-coil domain APG6_N PF17675.1 KXH44580.1 - 2.8 8.5 17.9 3.4 8.2 6.9 2.2 2 0 0 2 2 2 0 Apg6 coiled-coil region Occludin_ELL PF07303.13 KXH44580.1 - 3.6 8.4 8.9 2.2 9.0 1.3 2.4 2 0 0 2 2 2 0 Occludin homology domain SLC12 PF03522.15 KXH44580.1 - 9.3 5.1 9.6 5.9 5.8 5.5 1.9 1 1 1 2 2 2 0 Solute carrier family 12 Pex2_Pex12 PF04757.14 KXH44583.1 - 1.3e-36 126.3 1.8 2e-36 125.7 1.8 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.6 KXH44583.1 - 0.00017 21.7 4.6 0.00033 20.8 4.6 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 KXH44583.1 - 0.048 13.7 3.1 0.17 12.0 3.1 1.9 1 1 0 1 1 1 0 RING-type zinc-finger zf-C3HC4 PF00097.25 KXH44583.1 - 0.13 12.1 3.3 0.34 10.8 3.3 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXH44583.1 - 0.52 10.2 5.3 0.2 11.5 1.4 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Fungal_trans PF04082.18 KXH44584.1 - 5.7e-11 42.0 0.2 7.7e-11 41.5 0.2 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH44584.1 - 4.7e-08 33.0 7.8 9.9e-08 32.0 7.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain IBN_N PF03810.19 KXH44585.1 - 1.2e-14 54.0 0.3 5.3e-13 48.7 0.0 3.7 3 1 1 4 4 4 2 Importin-beta N-terminal domain Xpo1 PF08389.12 KXH44585.1 - 0.00078 19.5 0.0 0.0076 16.3 0.0 2.6 2 0 0 2 2 2 1 Exportin 1-like protein UME PF08064.13 KXH44585.1 - 0.12 12.2 0.2 0.84 9.6 0.1 2.5 2 0 0 2 2 2 0 UME (NUC010) domain ADH_zinc_N PF00107.26 KXH44586.1 - 2.4e-32 111.7 1.6 3.4e-32 111.1 1.6 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXH44586.1 - 5.6e-13 50.1 0.1 9.8e-13 49.3 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXH44586.1 - 2e-06 27.6 0.0 8.4e-06 25.6 0.0 2.0 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.18 KXH44586.1 - 0.011 16.0 0.1 0.02 15.1 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain AlaDh_PNT_C PF01262.21 KXH44586.1 - 0.036 13.4 5.2 0.03 13.6 3.7 1.5 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Form-deh_trans PF09163.11 KXH44586.1 - 0.26 11.1 0.1 0.26 11.1 0.1 2.9 3 1 0 3 3 3 0 Formate dehydrogenase N, transmembrane ubiquitin PF00240.23 KXH44587.1 - 4.3e-19 68.0 0.0 6.6e-19 67.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 KXH44587.1 - 3.1e-07 30.2 2.1 6.2e-06 26.0 0.0 2.6 2 0 0 2 2 2 1 UBA/TS-N domain Rad60-SLD_2 PF13881.6 KXH44587.1 - 0.00061 19.9 0.0 0.0011 19.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD PF11976.8 KXH44587.1 - 0.00076 19.3 0.1 0.0012 18.6 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 KXH44587.1 - 0.019 15.6 0.0 0.033 14.7 0.0 1.3 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain HOIP-UBA PF16678.5 KXH44587.1 - 0.024 14.6 0.0 0.04 13.9 0.0 1.3 1 0 0 1 1 1 0 HOIP UBA domain pair STI1 PF17830.1 KXH44587.1 - 0.28 11.1 22.3 0.24 11.4 3.4 3.5 3 0 0 3 3 3 0 STI1 domain NPR2 PF06218.11 KXH44588.1 - 2.3e-118 395.8 0.0 3.7e-98 329.2 0.0 2.2 1 1 1 2 2 2 2 Nitrogen permease regulator 2 RRM_4 PF10598.9 KXH44588.1 - 0.11 12.8 0.1 28 5.1 0.0 2.6 2 0 0 2 2 2 0 RNA recognition motif of the spliceosomal PrP8 tRNA-synt_1b PF00579.25 KXH44589.1 - 4.7e-78 262.5 0.0 6.9e-78 261.9 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) TyrRSs_C PF16714.5 KXH44589.1 - 4.2e-47 158.9 0.0 1.6e-46 157.0 0.0 1.9 2 0 0 2 2 2 1 Tyrosyl-tRNA synthetase C-terminal domain CybS PF05328.12 KXH44590.1 - 7e-50 168.2 0.0 9.1e-50 167.8 0.0 1.1 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit Sdh_cyt PF01127.22 KXH44590.1 - 0.01 15.8 0.5 0.5 10.4 0.1 2.2 1 1 1 2 2 2 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit MFS_1 PF07690.16 KXH44590.1 - 0.045 12.7 0.3 0.056 12.4 0.3 1.1 1 0 0 1 1 1 0 Major Facilitator Superfamily DUF3419 PF11899.8 KXH44591.1 - 3.9e-165 549.7 0.0 5.1e-165 549.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_23 PF13489.6 KXH44591.1 - 2.2e-12 47.1 0.0 2.1e-11 44.0 0.0 2.4 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH44591.1 - 6.7e-08 33.1 0.0 4.8e-05 24.0 0.0 3.8 4 0 0 4 4 4 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH44591.1 - 3.2e-07 31.0 0.0 2e-06 28.5 0.0 2.4 3 0 0 3 3 3 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXH44591.1 - 3.7e-07 29.7 0.1 0.001 18.5 0.0 2.7 3 0 0 3 3 3 2 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 KXH44591.1 - 4.5e-06 27.2 0.0 0.0012 19.4 0.0 3.7 4 0 0 4 4 4 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH44591.1 - 1.2e-05 25.2 0.0 6.9e-05 22.7 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain PCMT PF01135.19 KXH44591.1 - 0.0021 17.9 0.0 0.0042 16.9 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ada3 PF10198.9 KXH44592.1 - 7.6e-56 187.9 0.1 7.6e-56 187.9 0.1 3.3 3 1 0 3 3 3 1 Histone acetyltransferases subunit 3 Amidohydro_1 PF01979.20 KXH44594.1 - 1.6e-76 257.9 0.5 3.2e-76 256.9 0.4 1.5 2 0 0 2 2 2 1 Amidohydrolase family Urease_alpha PF00449.20 KXH44594.1 - 4.3e-55 185.2 1.5 4.3e-55 185.2 1.5 2.0 2 0 0 2 2 2 1 Urease alpha-subunit, N-terminal domain Urease_beta PF00699.20 KXH44594.1 - 4.6e-41 138.8 1.5 6.1e-41 138.4 0.1 2.0 3 0 0 3 3 3 1 Urease beta subunit Urease_gamma PF00547.18 KXH44594.1 - 7.9e-41 138.4 0.0 1.9e-40 137.2 0.0 1.7 1 0 0 1 1 1 1 Urease, gamma subunit Amidohydro_3 PF07969.11 KXH44594.1 - 1.1e-10 41.7 0.7 5.4e-07 29.4 0.0 2.3 1 1 0 2 2 2 2 Amidohydrolase family Amidohydro_2 PF04909.14 KXH44594.1 - 0.094 12.5 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 Amidohydrolase HMG_box PF00505.19 KXH44595.1 - 1.4e-07 31.8 0.3 3.2e-07 30.7 0.3 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KXH44595.1 - 0.00014 22.4 0.1 0.00045 20.8 0.1 1.9 1 0 0 1 1 1 1 HMG-box domain Het-C PF07217.11 KXH44597.1 - 6.3e-241 800.8 0.0 7.5e-241 800.5 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C Glyco_hydro_45 PF02015.16 KXH44598.1 - 5.8e-74 248.6 18.2 6.8e-74 248.3 18.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 zf-RING_2 PF13639.6 KXH44600.1 - 4.2e-12 46.2 6.5 7.6e-12 45.4 6.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KXH44600.1 - 2.8e-08 33.4 5.1 2.8e-08 33.4 5.1 1.8 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KXH44600.1 - 1.1e-07 31.5 5.2 2.4e-07 30.5 5.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXH44600.1 - 1.2e-06 28.3 5.3 2.2e-06 27.4 5.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXH44600.1 - 5.9e-06 26.1 4.2 1.1e-05 25.3 4.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 KXH44600.1 - 2.5e-05 24.5 3.0 6e-05 23.2 3.0 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 KXH44600.1 - 5.2e-05 23.0 3.9 8.9e-05 22.3 3.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXH44600.1 - 5.7e-05 23.0 1.9 5.7e-05 23.0 1.9 2.5 2 0 0 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KXH44600.1 - 5.9e-05 22.8 5.8 0.00012 21.9 5.8 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KXH44600.1 - 0.008 16.2 1.0 0.019 15.0 1.0 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 KXH44600.1 - 0.048 13.5 3.4 0.084 12.7 3.4 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Zn_ribbon_17 PF17120.5 KXH44600.1 - 0.058 13.0 2.3 0.11 12.1 2.3 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type TackOD1 PF18551.1 KXH44600.1 - 0.089 12.5 1.3 0.15 11.8 1.3 1.3 1 0 0 1 1 1 0 Thaumarchaeal output domain 1 MRC1 PF09444.10 KXH44600.1 - 0.24 11.9 0.8 0.71 10.4 0.1 1.9 2 0 0 2 2 2 0 MRC1-like domain Vps39_2 PF10367.9 KXH44600.1 - 0.63 10.5 3.4 0.28 11.6 0.5 1.9 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 RINGv PF12906.7 KXH44600.1 - 0.82 9.9 2.6 1.5 9.0 2.6 1.5 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_4 PF15227.6 KXH44600.1 - 0.88 9.8 6.1 2.1 8.6 6.1 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING PHD PF00628.29 KXH44600.1 - 1.3 9.0 3.7 2.7 7.9 3.7 1.6 1 0 0 1 1 1 0 PHD-finger DUF848 PF05852.11 KXH44601.1 - 0.052 13.7 1.1 0.3 11.2 0.2 2.4 2 1 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) SPC12 PF06645.13 KXH44601.1 - 0.15 12.1 0.8 0.3 11.2 0.8 1.4 1 0 0 1 1 1 0 Microsomal signal peptidase 12 kDa subunit (SPC12) TFIIS_M PF07500.14 KXH44602.1 - 1.3e-29 102.9 1.5 1.3e-29 102.9 1.5 1.9 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 KXH44602.1 - 1.6e-18 66.3 6.0 2.6e-18 65.6 6.0 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 KXH44602.1 - 7.5e-12 45.1 0.4 2.2e-11 43.6 0.4 1.8 1 0 0 1 1 1 1 TFIIS helical bundle-like domain CPSF100_C PF13299.6 KXH44602.1 - 0.065 13.4 0.6 0.065 13.4 0.6 2.5 2 1 1 3 3 3 0 Cleavage and polyadenylation factor 2 C-terminal DUF2868 PF11067.8 KXH44602.1 - 0.08 12.4 4.8 0.077 12.5 2.3 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2868) Ku_C PF03730.14 KXH44602.1 - 0.93 10.2 5.8 0.44 11.3 0.6 2.7 2 1 0 2 2 2 0 Ku70/Ku80 C-terminal arm PALP PF00291.25 KXH44603.1 - 2.4e-63 214.3 5.2 3e-63 214.0 5.2 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Methyltransf_28 PF02636.17 KXH44604.1 - 3.1e-34 118.8 0.0 4.8e-34 118.2 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PRMT5 PF05185.16 KXH44604.1 - 0.00077 19.3 0.0 0.0021 17.9 0.0 1.7 2 1 0 2 2 2 1 PRMT5 arginine-N-methyltransferase Chorion_2 PF03964.15 KXH44604.1 - 0.016 16.0 5.9 0.031 15.1 4.3 2.1 2 0 0 2 2 2 0 Chorion family 2 FAD_SOX PF18371.1 KXH44604.1 - 0.069 13.5 0.0 0.24 11.8 0.0 1.9 2 0 0 2 2 2 0 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase DUF3591 PF12157.8 KXH44605.1 - 1e-174 581.4 1.6 1.5e-174 580.8 1.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) Actin PF00022.19 KXH44606.1 - 6.3e-147 489.4 0.0 7.1e-147 489.3 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.13 KXH44606.1 - 6.1e-07 28.6 0.0 0.0013 17.6 0.0 2.3 2 0 0 2 2 2 2 MreB/Mbl protein PIG-P PF08510.12 KXH44607.1 - 1.6e-50 170.1 0.6 2.3e-50 169.5 0.6 1.2 1 0 0 1 1 1 1 PIG-P DPM2 PF07297.12 KXH44607.1 - 0.023 15.0 9.0 0.039 14.3 9.0 1.3 1 0 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) DUF485 PF04341.12 KXH44607.1 - 2.7 8.0 7.6 0.24 11.4 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF485 IBR PF01485.21 KXH44608.1 - 1.1e-07 31.9 1.6 1.1e-07 31.9 1.6 3.4 3 1 0 3 3 3 2 IBR domain, a half RING-finger domain FtsL PF04999.13 KXH44608.1 - 0.058 13.4 0.1 0.099 12.6 0.1 1.4 1 0 0 1 1 1 0 Cell division protein FtsL zf-C3HC4_3 PF13920.6 KXH44608.1 - 1.8 8.5 34.4 0.044 13.7 13.1 3.4 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Sugar_tr PF00083.24 KXH44609.1 - 1e-121 407.0 16.9 1.3e-121 406.6 16.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH44609.1 - 5.1e-22 78.3 35.8 7e-18 64.7 11.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sel1 PF08238.12 KXH44610.1 - 2.2e-37 126.7 41.7 0.00011 22.8 0.2 12.9 13 0 0 13 13 13 7 Sel1 repeat OPA3 PF07047.12 KXH44610.1 - 0.019 14.7 0.1 0.039 13.7 0.1 1.5 1 0 0 1 1 1 0 Optic atrophy 3 protein (OPA3) TPR_7 PF13176.6 KXH44610.1 - 0.046 13.8 2.1 1.7 8.9 0.1 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 KXH44610.1 - 0.39 11.5 17.5 0.88 10.4 0.7 6.7 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_1 PF00515.28 KXH44610.1 - 0.44 10.4 7.4 2.7 8.0 0.1 5.0 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.6 KXH44610.1 - 2 8.9 6.9 8.5 6.9 0.1 5.1 5 1 1 6 6 6 0 Tetratricopeptide repeat AIM3 PF17096.5 KXH44610.1 - 5.7 8.0 7.6 42 5.2 0.3 2.6 2 0 0 2 2 2 0 Altered inheritance of mitochondria protein 3 TPR_2 PF07719.17 KXH44610.1 - 8.1 6.8 12.1 11 6.5 0.2 6.1 6 0 0 6 6 6 0 Tetratricopeptide repeat WD40 PF00400.32 KXH44611.1 - 5.1e-12 46.1 4.8 0.021 15.7 0.0 5.5 6 0 0 6 6 6 3 WD domain, G-beta repeat DUF4948 PF16306.5 KXH44611.1 - 0.0099 15.7 0.2 0.016 15.0 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4948) Nucleoporin_N PF08801.11 KXH44611.1 - 0.017 13.9 0.0 7.6 5.2 0.0 3.1 2 1 1 3 3 3 0 Nup133 N terminal like FRG1 PF06229.12 KXH44612.1 - 6.1e-49 166.3 0.1 1.2e-48 165.4 0.1 1.4 1 0 0 1 1 1 1 FRG1-like domain Fascin PF06268.13 KXH44612.1 - 0.0049 17.1 0.0 0.02 15.1 0.0 2.0 2 0 0 2 2 2 1 Fascin domain 2OG-FeII_Oxy PF03171.20 KXH44613.1 - 0.00097 19.6 0.0 0.0046 17.4 0.0 2.1 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Thioredoxin_4 PF13462.6 KXH44614.1 - 2.4e-07 31.0 0.0 5.8e-07 29.8 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin DSBA PF01323.20 KXH44614.1 - 0.17 11.6 1.8 1.4 8.6 0.3 2.3 1 1 1 2 2 2 0 DSBA-like thioredoxin domain Fungal_trans PF04082.18 KXH44616.1 - 4e-09 35.9 0.0 8.8e-09 34.8 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH44616.1 - 5.7e-07 29.5 9.5 1.3e-06 28.4 9.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FeS_assembly_P PF01883.19 KXH44618.1 - 6.4e-07 29.5 0.0 2.6e-06 27.5 0.0 2.0 1 1 0 1 1 1 1 Iron-sulfur cluster assembly protein GTP_EFTU PF00009.27 KXH44619.1 - 1.1e-45 155.5 0.0 1.7e-45 155.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFTUD2 PF16004.5 KXH44619.1 - 6.9e-32 110.6 7.8 4.3e-31 108.0 7.8 2.3 1 1 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EFG_IV PF03764.18 KXH44619.1 - 9.4e-25 86.7 0.0 3.3e-24 85.0 0.0 2.0 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 KXH44619.1 - 1.3e-18 66.8 0.0 3.3e-18 65.5 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 KXH44619.1 - 2.6e-08 33.8 0.2 4.9e-07 29.7 0.0 2.5 2 0 0 2 2 2 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 KXH44619.1 - 6.1e-08 32.9 0.0 1.9e-07 31.4 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KXH44619.1 - 0.00027 21.0 0.1 0.00056 20.0 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Thiolase_N PF00108.23 KXH44620.1 - 1.1e-93 313.3 2.1 1.7e-93 312.7 2.1 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KXH44620.1 - 6.8e-47 158.1 0.2 1.8e-46 156.8 0.2 1.8 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KXH44620.1 - 4.9e-05 23.0 0.9 4.9e-05 23.0 0.9 2.1 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 KXH44620.1 - 0.015 15.1 1.4 1.6 8.6 0.1 2.9 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Myb_DNA-binding PF00249.31 KXH44629.1 - 2.5e-16 59.6 1.7 7.1e-09 35.7 0.2 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KXH44629.1 - 1e-09 38.5 0.3 0.0008 19.6 0.0 2.6 1 1 1 2 2 2 2 Myb-like DNA-binding domain Glyco_hydro_16 PF00722.21 KXH44630.1 - 6.7e-45 152.7 8.0 6.9e-45 152.7 4.1 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Chitin_bind_1 PF00187.19 KXH44630.1 - 5.7 7.5 21.6 0.076 13.5 13.4 2.1 2 0 0 2 2 2 0 Chitin recognition protein NAD_binding_10 PF13460.6 KXH44631.1 - 2.4e-19 69.9 0.0 2.9e-19 69.7 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KXH44631.1 - 0.011 15.3 0.0 0.018 14.6 0.0 1.4 2 0 0 2 2 2 0 NmrA-like family Lactonase PF10282.9 KXH44632.1 - 7.9e-55 186.5 0.5 2.5e-54 184.8 0.5 1.7 1 1 0 1 1 1 1 Lactonase, 7-bladed beta-propeller SBP56 PF05694.11 KXH44632.1 - 0.0019 17.1 0.0 0.18 10.6 0.0 2.1 2 0 0 2 2 2 2 56kDa selenium binding protein (SBP56) Cytochrom_D1 PF02239.16 KXH44632.1 - 0.055 12.0 0.0 0.25 9.9 0.0 2.0 1 1 1 2 2 2 0 Cytochrome D1 heme domain DUF4604 PF15377.6 KXH44633.1 - 1.1e-32 113.8 16.2 1.2e-32 113.7 16.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) COX5B PF01215.19 KXH44634.1 - 7e-56 187.4 0.0 9e-56 187.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb PKcGMP_CC PF16808.5 KXH44635.1 - 0.00083 19.2 10.3 0.0096 15.8 5.5 2.6 2 0 0 2 2 2 2 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF1192 PF06698.11 KXH44635.1 - 0.0014 18.6 4.7 0.76 9.9 0.0 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF1192) ERM PF00769.19 KXH44635.1 - 0.012 15.5 2.5 0.012 15.5 2.5 2.2 2 0 0 2 2 2 0 Ezrin/radixin/moesin family Tnp_22_trimer PF17489.2 KXH44635.1 - 0.038 14.0 2.4 3 7.9 0.3 2.6 2 0 0 2 2 2 0 L1 transposable element trimerization domain TMF_DNA_bd PF12329.8 KXH44635.1 - 0.11 12.6 0.2 0.11 12.6 0.2 3.1 4 0 0 4 4 4 0 TATA element modulatory factor 1 DNA binding Cauli_DNA-bind PF03310.13 KXH44635.1 - 0.22 11.6 6.0 0.58 10.2 5.8 1.8 1 1 0 1 1 1 0 Caulimovirus DNA-binding protein Atg14 PF10186.9 KXH44635.1 - 3.6 6.6 15.1 0.036 13.2 4.6 2.2 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Spc7 PF08317.11 KXH44635.1 - 6.3 5.6 14.6 0.28 10.0 6.7 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein Prefoldin PF02996.17 KXH44635.1 - 7.5 6.5 8.2 2.7 7.9 4.0 2.2 2 0 0 2 2 2 0 Prefoldin subunit 4HBT_3 PF13622.6 KXH44636.1 - 7.6e-22 78.8 0.0 9.4e-22 78.5 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Amino_oxidase PF01593.24 KXH44638.1 - 4.4e-62 210.9 0.4 7e-62 210.2 0.4 1.3 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KXH44638.1 - 4.1e-16 59.0 0.8 8.6e-16 57.9 0.3 1.9 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXH44638.1 - 5.5e-10 39.4 1.4 1.2e-09 38.3 1.4 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KXH44638.1 - 5.3e-07 28.7 0.5 0.00013 20.8 0.1 2.2 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_2 PF07992.14 KXH44638.1 - 7.4e-07 28.7 1.4 0.001 18.4 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXH44638.1 - 9.5e-07 29.3 2.0 0.002 18.6 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXH44638.1 - 2.3e-06 27.0 1.2 7.5e-06 25.3 1.2 1.8 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 KXH44638.1 - 5.1e-06 26.1 0.6 2e-05 24.2 0.4 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 KXH44638.1 - 0.00018 20.8 0.2 0.00035 19.9 0.2 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 KXH44638.1 - 0.001 18.4 0.4 0.0063 15.8 0.1 2.0 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.22 KXH44638.1 - 0.0019 17.4 0.4 0.0036 16.4 0.4 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 KXH44638.1 - 0.003 16.9 0.8 0.089 12.0 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXH44638.1 - 0.0056 16.7 0.2 3.1 7.8 0.0 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KXH44638.1 - 0.015 14.4 0.7 0.034 13.2 0.5 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein HlyE PF06109.13 KXH44638.1 - 0.13 11.6 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Haemolysin E (HlyE) OHCU_decarbox PF09349.10 KXH44639.1 - 1.7e-41 142.3 0.3 2e-41 142.0 0.3 1.0 1 0 0 1 1 1 1 OHCU decarboxylase Dor1 PF04124.12 KXH44639.1 - 0.043 12.5 0.2 0.051 12.3 0.2 1.1 1 0 0 1 1 1 0 Dor1-like family LRR_12 PF18837.1 KXH44639.1 - 3.2 7.5 7.7 12 5.6 0.0 3.0 4 0 0 4 4 4 0 Leucine-rich repeat Prp19 PF08606.11 KXH44640.1 - 8.6e-33 112.1 2.6 1.9e-32 111.1 2.6 1.6 1 0 0 1 1 1 1 Prp19/Pso4-like ANAPC4_WD40 PF12894.7 KXH44640.1 - 1.1e-12 48.1 0.0 4.9e-06 26.7 0.0 4.4 1 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KXH44640.1 - 1.5e-10 41.5 0.5 0.0099 16.7 0.0 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 KXH44640.1 - 7.9e-05 21.9 0.0 0.0064 15.6 0.0 2.1 1 1 1 2 2 2 2 Coatomer WD associated region V_ATPase_I_N PF18670.1 KXH44640.1 - 0.0012 19.2 0.4 0.0039 17.6 0.4 1.9 2 0 0 2 2 2 1 V-type ATPase subunit I, N-terminal domain eIF2A PF08662.11 KXH44640.1 - 0.0012 18.7 0.0 1.7 8.5 0.0 2.4 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A U-box PF04564.15 KXH44640.1 - 0.0017 18.5 0.0 0.0034 17.5 0.0 1.5 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 KXH44640.1 - 0.0026 17.6 0.0 0.0059 16.4 0.0 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Lactonase PF10282.9 KXH44640.1 - 0.021 14.1 0.0 0.07 12.4 0.0 1.9 2 1 1 3 3 3 0 Lactonase, 7-bladed beta-propeller VID27 PF08553.10 KXH44640.1 - 0.068 12.2 0.3 0.17 10.9 0.1 1.7 2 0 0 2 2 2 0 VID27 C-terminal WD40-like domain HPS3_N PF14761.6 KXH44640.1 - 0.074 12.6 0.0 2.1 7.8 0.0 2.5 2 1 0 2 2 2 0 Hermansky-Pudlak syndrome 3 EP400_N PF15790.5 KXH44641.1 - 1.5 7.6 7.8 2.5 6.8 7.8 1.3 1 0 0 1 1 1 0 E1A-binding protein p400, N-terminal Stealth_CR4 PF17103.5 KXH44642.1 - 0.13 12.2 0.3 0.47 10.4 0.1 2.1 2 0 0 2 2 2 0 Stealth protein CR4, conserved region 4 Borrelia_P83 PF05262.11 KXH44642.1 - 4.6 5.6 14.2 8 4.8 14.2 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein WD40 PF00400.32 KXH44643.1 - 2e-15 56.9 6.3 1.6e-06 28.7 0.1 4.7 4 0 0 4 4 4 3 WD domain, G-beta repeat CAF1C_H4-bd PF12265.8 KXH44643.1 - 1.3e-13 51.0 0.0 5.6e-13 48.9 0.0 2.2 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex ANAPC4_WD40 PF12894.7 KXH44643.1 - 1.1e-09 38.4 0.4 0.0054 17.0 0.1 4.3 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Amidoligase_2 PF12224.8 KXH44646.1 - 6.3e-17 62.1 0.0 6e-16 58.9 0.0 2.0 1 1 0 1 1 1 1 Putative amidoligase enzyme Thioredoxin PF00085.20 KXH44647.1 - 5.5e-24 84.1 0.0 9.4e-24 83.4 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 KXH44647.1 - 1.7e-06 27.6 0.0 1.8e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 KXH44647.1 - 7e-06 26.5 0.4 4.3e-05 23.9 0.1 2.2 1 1 1 2 2 2 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KXH44647.1 - 5.2e-05 23.5 0.0 0.00036 20.8 0.0 2.0 1 1 0 1 1 1 1 Thioredoxin-like TraF PF13728.6 KXH44647.1 - 0.0087 15.9 1.3 0.03 14.1 0.0 1.9 2 0 0 2 2 2 1 F plasmid transfer operon protein Thioredoxin_7 PF13899.6 KXH44647.1 - 0.0088 16.2 0.0 0.0088 16.2 0.0 1.9 2 0 0 2 2 2 1 Thioredoxin-like HyaE PF07449.11 KXH44647.1 - 0.062 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Thioredoxin_9 PF14595.6 KXH44647.1 - 0.11 12.3 0.1 0.43 10.3 0.0 1.8 1 1 1 2 2 2 0 Thioredoxin Thioredoxin_5 PF13743.6 KXH44647.1 - 0.14 11.8 0.0 0.37 10.5 0.0 1.7 1 1 1 2 2 2 0 Thioredoxin WD40 PF00400.32 KXH44648.1 - 8.4e-27 92.9 13.8 9.4e-07 29.4 0.1 6.9 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXH44648.1 - 5.2e-05 23.5 0.6 0.38 11.1 0.0 4.8 2 1 4 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KXH44648.1 - 0.011 14.7 5.5 0.062 12.3 0.3 3.4 1 1 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 KXH44648.1 - 0.072 12.4 0.2 2.4 7.4 0.0 3.2 4 0 0 4 4 4 0 Neuroblastoma-amplified sequence, N terminal Nudix_N_2 PF14803.6 KXH44648.1 - 0.48 10.4 1.7 1.5 8.8 1.7 1.8 1 0 0 1 1 1 0 Nudix N-terminal eRF1_1 PF03463.15 KXH44649.1 - 3.1e-25 88.6 0.0 5.7e-25 87.8 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.15 KXH44649.1 - 3.8e-19 69.3 0.0 6.7e-19 68.5 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 KXH44649.1 - 4.5e-16 59.3 0.0 8.2e-16 58.5 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 3 Aldo_ket_red PF00248.21 KXH44650.1 - 4.3e-36 124.6 0.0 1.6e-33 116.2 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family NmrA PF05368.13 KXH44652.1 - 7.9e-14 51.8 0.0 1e-13 51.4 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXH44652.1 - 2e-11 44.1 0.0 3.3e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KXH44652.1 - 0.0021 17.6 0.1 0.003 17.1 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.20 KXH44652.1 - 0.0065 16.6 0.4 0.018 15.2 0.4 1.8 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus KR PF08659.10 KXH44652.1 - 0.033 14.1 0.1 0.058 13.3 0.1 1.4 1 0 0 1 1 1 0 KR domain ApbA PF02558.16 KXH44652.1 - 0.079 12.6 0.2 0.13 11.9 0.2 1.4 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.20 KXH44652.1 - 0.16 12.0 0.1 0.27 11.3 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase p450 PF00067.22 KXH44653.1 - 1e-47 163.0 0.0 1.4e-47 162.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 TauD PF02668.16 KXH44655.1 - 2.4e-42 145.6 0.4 3.1e-42 145.2 0.4 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family OTT_1508_deam PF14441.6 KXH44658.1 - 5.5e-16 58.3 3.4 1.5e-15 57.0 2.4 2.3 2 0 0 2 2 2 1 OTT_1508-like deaminase Peptidase_M49 PF03571.15 KXH44658.1 - 0.015 13.7 0.1 0.022 13.1 0.1 1.1 1 0 0 1 1 1 0 Peptidase family M49 Csa1 PF06023.12 KXH44658.1 - 0.027 13.8 0.1 0.042 13.2 0.1 1.3 1 0 0 1 1 1 0 CRISPR-associated exonuclease Csa1 Carb_anhydrase PF00194.21 KXH44659.1 - 2.4e-34 119.0 0.1 3.3e-34 118.6 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Polyketide_cyc2 PF10604.9 KXH44660.1 - 1.3e-16 61.2 0.0 1.5e-16 60.9 0.0 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 KXH44660.1 - 0.12 12.5 0.0 0.14 12.4 0.0 1.4 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport ADH_zinc_N PF00107.26 KXH44661.1 - 9.9e-10 38.5 0.1 1.6e-09 37.8 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXH44661.1 - 2.5e-07 30.6 0.0 5.7e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain DUF218 PF02698.17 KXH44662.1 - 6.1e-08 32.8 0.0 1.3e-07 31.7 0.0 1.6 1 1 0 1 1 1 1 DUF218 domain DUF3328 PF11807.8 KXH44663.1 - 1.2e-05 25.2 1.5 2.3e-05 24.3 1.5 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) Pyr_redox_2 PF07992.14 KXH44664.1 - 0.017 14.4 0.0 3 7.0 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 KXH44664.1 - 0.035 13.5 0.0 0.06 12.7 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KXH44664.1 - 0.085 12.9 0.0 0.23 11.5 0.0 1.7 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Spidroin_MaSp PF11260.8 KXH44665.1 - 0.52 10.7 3.0 19 5.6 0.3 2.3 2 0 0 2 2 2 0 Major ampullate spidroin 1 and 2 Mito_carr PF00153.27 KXH44721.1 - 3.4e-45 151.9 7.8 1.3e-15 57.1 0.2 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein UCH PF00443.29 KXH44722.1 - 3e-54 184.2 0.0 1.2e-53 182.3 0.0 2.0 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KXH44722.1 - 4e-26 92.4 0.2 1.4e-19 70.8 0.0 2.5 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Macoilin PF09726.9 KXH44722.1 - 1.7 7.1 13.4 2.6 6.5 13.4 1.2 1 0 0 1 1 1 0 Macoilin family Peptidase_C98 PF15499.6 KXH44722.1 - 5.9 6.3 12.2 0.3 10.5 0.9 3.2 4 0 0 4 4 4 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Presenilin PF01080.17 KXH44722.1 - 7.1 5.3 11.4 12 4.5 11.4 1.5 1 0 0 1 1 1 0 Presenilin Yos1 PF08571.10 KXH44723.1 - 2.4e-21 75.8 0.0 7.9e-21 74.1 0.0 1.8 1 1 0 1 1 1 1 Yos1-like Glyco_transf_22 PF03901.17 KXH44724.1 - 5.5e-41 141.2 12.1 6.9e-41 140.8 12.1 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family PP2C PF00481.21 KXH44725.1 - 1.6e-59 201.6 0.0 1.4e-58 198.6 0.0 2.3 2 0 0 2 2 2 1 Protein phosphatase 2C LRR_8 PF13855.6 KXH44725.1 - 1.6e-33 114.3 67.0 2.3e-09 36.9 1.1 10.5 4 3 8 12 12 12 10 Leucine rich repeat LRR_4 PF12799.7 KXH44725.1 - 1.4e-31 108.0 74.5 0.00017 21.9 0.1 13.0 8 1 4 14 14 14 10 Leucine Rich repeats (2 copies) Guanylate_cyc PF00211.20 KXH44725.1 - 5.3e-31 107.7 0.1 3.2e-30 105.1 0.0 2.0 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain Ad_cyc_g-alpha PF08509.11 KXH44725.1 - 5.2e-15 54.9 0.8 2.1e-14 53.0 0.8 2.1 1 0 0 1 1 1 1 Adenylate cyclase G-alpha binding domain LRR_1 PF00560.33 KXH44725.1 - 3.3e-05 23.9 54.2 13 6.8 0.1 16.7 17 2 0 17 17 17 3 Leucine Rich Repeat LRR_9 PF14580.6 KXH44725.1 - 0.002 17.7 22.9 0.054 13.0 2.8 4.5 2 1 1 4 4 4 3 Leucine-rich repeat LRR_6 PF13516.6 KXH44725.1 - 1.1 9.4 42.9 3.4 7.9 0.3 11.9 13 0 0 13 13 13 0 Leucine Rich repeat Aldo_ket_red PF00248.21 KXH44727.1 - 1.5e-70 237.7 0.0 1.7e-70 237.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Alpha-amylase PF00128.24 KXH44728.1 - 3.3e-115 385.3 0.2 5.4e-115 384.6 0.2 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 KXH44728.1 - 3.8e-06 26.9 0.0 7e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain Alpha-amylase_C PF02806.18 KXH44728.1 - 0.0099 16.3 0.0 0.03 14.8 0.0 1.8 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Fungal_trans PF04082.18 KXH44729.1 - 5.4e-09 35.5 0.0 8.7e-09 34.8 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH44729.1 - 4.3e-08 33.1 5.6 7.1e-08 32.5 5.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 KXH44730.1 - 5.7e-22 78.1 21.9 7.7e-22 77.7 21.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily TauD PF02668.16 KXH44731.1 - 8e-55 186.5 0.0 1.7e-54 185.5 0.0 1.4 2 0 0 2 2 2 1 Taurine catabolism dioxygenase TauD, TfdA family RTC4 PF14474.6 KXH44732.1 - 1.9e-31 108.7 0.0 4.2e-31 107.6 0.0 1.6 1 0 0 1 1 1 1 RTC4-like domain Dynamitin PF04912.14 KXH44733.1 - 4.2e-96 322.6 4.7 5.2e-96 322.3 4.7 1.0 1 0 0 1 1 1 1 Dynamitin FH2 PF02181.23 KXH44733.1 - 0.0015 17.7 3.0 0.16 11.1 0.0 3.0 3 0 0 3 3 3 1 Formin Homology 2 Domain RPN7 PF10602.9 KXH44733.1 - 0.0019 17.9 1.4 0.0035 17.1 0.4 1.9 2 0 0 2 2 2 1 26S proteasome subunit RPN7 DHR10 PF18595.1 KXH44733.1 - 0.0029 17.6 17.4 4.6 7.3 2.8 4.7 3 1 2 5 5 5 1 Designed helical repeat protein 10 domain Spore_III_AB PF09548.10 KXH44733.1 - 0.0033 17.5 2.4 0.056 13.6 0.1 3.3 3 1 0 3 3 3 1 Stage III sporulation protein AB (spore_III_AB) ATF7IP_BD PF16788.5 KXH44733.1 - 0.0081 16.3 0.4 0.0081 16.3 0.4 1.6 2 0 0 2 2 1 1 ATF-interacting protein binding domain SKA1 PF07160.12 KXH44733.1 - 0.023 14.5 5.0 6 6.7 0.6 3.1 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 1 BLOC1_2 PF10046.9 KXH44733.1 - 0.039 14.3 5.7 25 5.2 0.1 3.9 3 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 IFT57 PF10498.9 KXH44733.1 - 0.042 12.8 4.2 0.61 9.0 0.0 3.0 3 0 0 3 3 3 0 Intra-flagellar transport protein 57 Fib_alpha PF08702.10 KXH44733.1 - 0.056 13.6 2.5 32 4.7 0.0 3.5 3 1 0 3 3 3 0 Fibrinogen alpha/beta chain family ATP-synt_E PF05680.12 KXH44733.1 - 0.088 13.2 6.1 0.069 13.5 0.9 2.6 2 0 0 2 2 2 0 ATP synthase E chain KxDL PF10241.9 KXH44733.1 - 0.089 13.1 2.3 9.1 6.6 0.0 3.4 3 1 0 3 3 3 0 Uncharacterized conserved protein Laminin_II PF06009.12 KXH44733.1 - 0.1 12.6 10.6 0.62 10.1 0.1 3.9 2 1 2 4 4 4 0 Laminin Domain II Corazonin PF17308.2 KXH44733.1 - 0.13 12.7 0.5 0.32 11.3 0.3 1.8 1 1 0 1 1 1 0 Pro-corazonin GrpE PF01025.19 KXH44733.1 - 0.16 11.6 4.4 0.36 10.5 1.1 2.7 3 0 0 3 3 3 0 GrpE Matrilin_ccoil PF10393.9 KXH44733.1 - 0.16 11.8 0.5 18 5.3 0.2 2.7 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin YojJ PF10372.9 KXH44733.1 - 0.19 11.8 0.3 1.2 9.3 0.0 2.4 3 1 1 4 4 2 0 Bacterial membrane-spanning protein N-terminus DUF745 PF05335.13 KXH44733.1 - 0.22 11.2 9.5 1.4 8.7 0.8 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF745) Allexi_40kDa PF05549.11 KXH44733.1 - 0.28 10.7 4.2 4.7 6.6 0.9 2.9 3 0 0 3 3 3 0 Allexivirus 40kDa protein SOGA PF11365.8 KXH44733.1 - 0.32 12.1 6.2 2 9.6 0.0 3.2 3 0 0 3 3 3 0 Protein SOGA ZapB PF06005.12 KXH44733.1 - 0.34 11.4 9.3 0.4 11.2 0.9 3.3 3 0 0 3 3 3 0 Cell division protein ZapB Baculo_PEP_C PF04513.12 KXH44733.1 - 0.44 10.6 3.4 8.4 6.4 1.3 2.9 2 2 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus WXG100 PF06013.12 KXH44733.1 - 0.45 10.8 6.2 7.3 6.9 0.0 3.6 3 1 0 3 3 3 0 Proteins of 100 residues with WXG CENP-F_leu_zip PF10473.9 KXH44733.1 - 0.51 10.4 11.8 3.3 7.7 3.5 3.2 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Phage_GP20 PF06810.11 KXH44733.1 - 0.52 10.1 11.5 0.068 13.0 1.8 3.2 3 1 0 3 3 3 0 Phage minor structural protein GP20 Cytochrom_B562 PF07361.11 KXH44733.1 - 0.57 10.9 9.0 0.64 10.7 0.6 3.3 3 1 0 3 3 3 0 Cytochrome b562 DUF1192 PF06698.11 KXH44733.1 - 0.62 10.2 7.0 2.6 8.1 1.5 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) DUF724 PF05266.14 KXH44733.1 - 0.69 9.7 10.6 1.1 9.0 0.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF724) FlgN PF05130.12 KXH44733.1 - 1.4 9.4 13.8 0.056 14.0 3.2 2.9 2 1 1 3 3 3 0 FlgN protein STAT_alpha PF01017.20 KXH44733.1 - 1.9 8.3 5.7 3.2 7.6 2.1 2.9 2 1 1 3 3 3 0 STAT protein, all-alpha domain Prefoldin_2 PF01920.20 KXH44733.1 - 2.5 8.1 11.2 17 5.4 0.1 4.0 3 1 1 4 4 4 0 Prefoldin subunit DUF2203 PF09969.9 KXH44733.1 - 2.5 8.8 9.4 35 5.2 0.6 3.6 3 1 1 4 4 3 0 Uncharacterized conserved protein (DUF2203) DASH_Spc19 PF08287.11 KXH44733.1 - 3.4 7.5 14.1 0.29 11.0 2.7 2.7 2 2 0 2 2 2 0 Spc19 DUF4407 PF14362.6 KXH44733.1 - 3.6 6.8 14.6 3.1e+02 0.5 14.6 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) MIP-T3_C PF17749.1 KXH44733.1 - 5.3 7.0 11.3 6.8 6.6 0.3 3.0 3 0 0 3 3 3 0 Microtubule-binding protein MIP-T3 C-terminal region Muted PF14942.6 KXH44733.1 - 6.3 7.1 7.8 5.9 7.2 0.1 2.9 3 0 0 3 3 3 0 Organelle biogenesis, Muted-like protein Fmp27_WPPW PF10359.9 KXH44733.1 - 7.9 5.2 8.0 0.69 8.7 1.3 2.1 2 1 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain APG6_N PF17675.1 KXH44733.1 - 9.6 6.7 16.6 24 5.4 0.3 3.4 3 1 0 3 3 3 0 Apg6 coiled-coil region Syntaxin-6_N PF09177.11 KXH44733.1 - 9.7 6.8 7.5 41 4.8 1.2 3.5 3 0 0 3 3 3 0 Syntaxin 6, N-terminal Ribosomal_S28e PF01200.18 KXH44734.1 - 1.4e-31 108.3 2.0 1.5e-31 108.1 2.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e ThiS PF02597.20 KXH44735.1 - 4.3e-10 40.1 0.0 5.7e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 ThiS family PSI PF01437.25 KXH44736.1 - 0.00013 22.5 7.9 0.00021 21.7 7.9 1.4 1 0 0 1 1 1 1 Plexin repeat VirB3 PF05101.13 KXH44736.1 - 0.043 14.1 1.1 0.087 13.1 1.1 1.4 1 0 0 1 1 1 0 Type IV secretory pathway, VirB3-like protein Sugar_tr PF00083.24 KXH44737.1 - 5.5e-84 282.6 18.1 6.8e-84 282.3 18.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH44737.1 - 1.3e-26 93.4 33.8 2.5e-20 72.7 10.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KXH44737.1 - 0.0036 15.8 0.7 0.0036 15.8 0.7 2.2 2 1 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) IBR PF01485.21 KXH44738.1 - 5.3e-07 29.8 24.0 3.5e-05 23.9 11.7 3.5 3 1 0 3 3 3 2 IBR domain, a half RING-finger domain Mo-nitro_C PF06967.11 KXH44738.1 - 0.089 12.8 1.3 1.3 9.1 1.5 2.4 2 0 0 2 2 2 0 Mo-dependent nitrogenase C-terminus FAA_hydrolase PF01557.18 KXH44739.1 - 1.5e-62 211.2 0.0 1.8e-62 210.9 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family SNF2_N PF00176.23 KXH44741.1 - 1.6e-50 171.8 0.0 2.7e-50 171.0 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KXH44741.1 - 2.4e-17 63.3 0.3 6.5e-17 61.9 0.3 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 KXH44741.1 - 8.5e-05 21.9 1.1 0.00017 20.9 0.1 1.8 1 1 1 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase UBA PF00627.31 KXH44741.1 - 0.0017 18.2 0.2 0.004 17.0 0.2 1.7 1 0 0 1 1 1 1 UBA/TS-N domain HBS1_N PF08938.10 KXH44741.1 - 0.026 14.8 4.4 0.03 14.6 0.1 2.9 2 0 0 2 2 2 0 HBS1 N-terminus CUE PF02845.16 KXH44741.1 - 0.1 12.3 0.1 0.24 11.1 0.1 1.7 1 0 0 1 1 1 0 CUE domain VMA21 PF09446.10 KXH44742.1 - 5.2e-16 58.5 8.1 7.6e-16 58.0 8.1 1.3 1 0 0 1 1 1 1 VMA21-like domain DUF2406 PF10295.9 KXH44743.1 - 2.7e-26 92.0 0.5 2.7e-26 92.0 0.5 2.2 2 0 0 2 2 2 1 Uncharacterised protein (DUF2406) KIAA1328 PF15369.6 KXH44743.1 - 0.2 11.5 3.6 0.37 10.6 3.6 1.5 1 0 0 1 1 1 0 Uncharacterised protein KIAA1328 CorA PF01544.18 KXH44745.1 - 2.3e-41 142.0 0.1 6e-41 140.7 0.1 1.6 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Osmo_CC PF08946.10 KXH44745.1 - 0.032 14.5 0.6 0.082 13.2 0.6 1.6 1 0 0 1 1 1 0 Osmosensory transporter coiled coil CBF PF03914.17 KXH44746.1 - 2e-32 112.6 0.2 2e-32 112.6 0.2 2.3 2 2 1 3 3 3 1 CBF/Mak21 family Mt_ATP-synt_B PF05405.14 KXH44747.1 - 1.4e-53 180.8 2.7 1.8e-53 180.5 2.7 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) tRNA_anti-codon PF01336.25 KXH44747.1 - 0.1 12.6 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain MSC PF09402.10 KXH44748.1 - 5.7e-117 391.0 0.0 7.4e-117 390.6 0.0 1.1 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.7 KXH44748.1 - 4.6e-18 64.6 0.1 9.1e-18 63.7 0.1 1.5 1 0 0 1 1 1 1 HeH/LEM domain Thymopoietin PF08198.11 KXH44748.1 - 0.0034 17.0 0.0 0.0088 15.6 0.0 1.6 1 0 0 1 1 1 1 Thymopoietin protein FAD_binding_3 PF01494.19 KXH44749.1 - 6e-25 88.2 0.0 2.1e-23 83.1 0.0 2.1 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 KXH44749.1 - 5.1e-05 22.5 0.2 0.0089 15.1 0.0 2.6 3 0 0 3 3 3 2 Lycopene cyclase protein DAO PF01266.24 KXH44749.1 - 0.00015 21.4 0.0 0.56 9.7 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase SE PF08491.10 KXH44749.1 - 0.0004 19.5 0.0 0.00062 18.9 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase Pyr_redox_2 PF07992.14 KXH44749.1 - 0.0034 16.6 0.0 0.023 13.9 0.0 2.0 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXH44749.1 - 0.0042 17.1 0.0 0.01 15.8 0.0 1.6 1 0 0 1 1 1 1 FAD-NAD(P)-binding Thi4 PF01946.17 KXH44749.1 - 0.041 13.1 0.0 0.67 9.1 0.0 2.1 2 0 0 2 2 2 0 Thi4 family NAD_binding_8 PF13450.6 KXH44749.1 - 0.061 13.6 0.0 0.17 12.1 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KXH44749.1 - 0.07 12.3 0.1 0.18 10.9 0.0 1.7 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.14 KXH44749.1 - 0.12 11.2 0.0 1.6 7.5 0.0 2.2 2 0 0 2 2 2 0 Tryptophan halogenase PLAC9 PF15205.6 KXH44749.1 - 0.24 11.8 0.5 35 4.9 0.0 3.8 4 0 0 4 4 4 0 Placenta-specific protein 9 Complex1_49kDa PF00346.19 KXH44750.1 - 4.6e-123 409.6 0.0 6.4e-123 409.1 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.19 KXH44750.1 - 0.03 13.2 0.0 0.059 12.3 0.0 1.4 1 1 0 1 1 1 0 Nickel-dependent hydrogenase SNase PF00565.17 KXH44751.1 - 4.2e-21 75.5 0.0 6.1e-21 74.9 0.0 1.2 1 0 0 1 1 1 1 Staphylococcal nuclease homologue Pkinase PF00069.25 KXH44752.1 - 2.3e-54 184.5 0.0 3.2e-54 184.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXH44752.1 - 4.1e-41 141.0 0.0 6.5e-41 140.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXH44752.1 - 0.0021 17.4 0.0 0.026 13.8 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KXH44752.1 - 0.02 14.8 0.0 0.15 12.0 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXH44752.1 - 0.025 13.4 0.0 0.1 11.3 0.0 1.9 2 0 0 2 2 2 0 Fungal protein kinase Haspin_kinase PF12330.8 KXH44752.1 - 0.09 11.7 0.0 1.4 7.7 0.0 2.1 2 0 0 2 2 2 0 Haspin like kinase domain Telomere_reg-2 PF10193.9 KXH44753.1 - 2e-36 124.7 0.0 1.1e-35 122.4 0.0 2.4 2 0 0 2 2 2 1 Telomere length regulation protein ThiF PF00899.21 KXH44754.1 - 1e-63 215.0 0.1 1.4e-63 214.5 0.1 1.1 1 0 0 1 1 1 1 ThiF family E2_bind PF08825.10 KXH44754.1 - 6.1e-30 103.2 0.1 1e-29 102.5 0.1 1.4 1 0 0 1 1 1 1 E2 binding domain Shikimate_DH PF01488.20 KXH44754.1 - 0.00015 21.9 0.5 0.00035 20.6 0.0 1.8 2 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase UAE_UbL PF14732.6 KXH44754.1 - 0.00029 21.4 0.1 0.0065 17.0 0.0 2.4 2 0 0 2 2 2 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain Sacchrp_dh_NADP PF03435.18 KXH44754.1 - 0.038 14.2 0.1 0.11 12.7 0.1 1.9 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_7 PF13241.6 KXH44754.1 - 0.053 14.0 0.1 0.13 12.7 0.1 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox PF00070.27 KXH44754.1 - 0.12 12.9 0.0 0.27 11.8 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase E1_UFD PF09358.10 KXH44754.1 - 0.16 12.7 0.1 0.67 10.7 0.0 2.0 2 0 0 2 2 2 0 Ubiquitin fold domain UBA_e1_thiolCys PF10585.9 KXH44754.1 - 0.28 11.1 2.7 10 6.0 0.0 2.4 1 1 1 2 2 2 0 Ubiquitin-activating enzyme active site RNA_pol_A_bac PF01000.26 KXH44755.1 - 9.9e-28 96.8 0.0 2e-27 95.8 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 KXH44755.1 - 1.6e-19 69.1 0.0 2.7e-19 68.4 0.0 1.4 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain EKLF_TAD2 PF16833.5 KXH44755.1 - 0.41 10.7 0.1 0.41 10.7 0.1 1.7 2 0 0 2 2 2 0 Erythroid krueppel-like transcription factor, transactivation 2 BTB_2 PF02214.22 KXH44756.1 - 0.00045 20.5 0.1 0.00091 19.5 0.1 1.5 1 0 0 1 1 1 1 BTB/POZ domain OTT_1508_deam PF14441.6 KXH44757.1 - 1.7e-18 66.3 0.2 4.5e-18 65.0 0.2 1.8 1 0 0 1 1 1 1 OTT_1508-like deaminase Herpes_UL1 PF05259.11 KXH44758.1 - 0.037 14.1 0.0 0.069 13.2 0.0 1.4 1 0 0 1 1 1 0 Herpesvirus glycoprotein L RE_SinI PF09570.10 KXH44758.1 - 0.13 11.5 0.0 0.24 10.6 0.0 1.4 1 0 0 1 1 1 0 SinI restriction endonuclease AAA PF00004.29 KXH44759.1 - 8.4e-54 181.6 0.0 3e-43 147.4 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.11 KXH44759.1 - 2e-28 98.6 1.7 2.6e-28 98.2 0.3 2.0 2 0 0 2 2 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_lid_3 PF17862.1 KXH44759.1 - 1.3e-11 44.1 2.5 8.8e-09 35.0 0.0 3.4 4 0 0 4 4 3 2 AAA+ lid domain AAA_16 PF13191.6 KXH44759.1 - 1.6e-11 44.9 3.9 1.5e-05 25.4 0.1 4.2 2 2 2 4 4 4 2 AAA ATPase domain NACHT PF05729.12 KXH44759.1 - 5e-08 33.0 0.5 4.8e-05 23.3 0.0 3.2 3 0 0 3 3 3 1 NACHT domain RuvB_N PF05496.12 KXH44759.1 - 2.5e-06 27.3 0.0 0.014 15.1 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 KXH44759.1 - 7.5e-06 26.0 0.1 0.016 15.2 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE TIP49 PF06068.13 KXH44759.1 - 8.6e-06 25.2 0.0 0.017 14.3 0.0 2.2 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_33 PF13671.6 KXH44759.1 - 9.5e-06 25.8 0.0 0.25 11.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KXH44759.1 - 1.2e-05 25.8 0.1 0.035 14.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.14 KXH44759.1 - 2.1e-05 24.7 0.0 0.26 11.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KXH44759.1 - 2.3e-05 24.7 1.5 0.19 12.0 0.1 3.7 2 2 1 3 3 3 1 AAA domain AAA_14 PF13173.6 KXH44759.1 - 0.00016 21.7 0.0 0.26 11.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 KXH44759.1 - 0.00017 21.1 0.0 0.0068 15.9 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_5 PF07728.14 KXH44759.1 - 0.0002 21.4 0.2 0.85 9.6 0.0 2.9 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) PEX-2N PF09263.10 KXH44759.1 - 0.00051 20.3 1.1 0.64 10.4 0.0 3.1 2 1 0 2 2 2 1 Peroxisome biogenesis factor 1, N-terminal RNA_helicase PF00910.22 KXH44759.1 - 0.0013 19.1 0.0 2 8.8 0.0 2.6 2 0 0 2 2 2 1 RNA helicase IstB_IS21 PF01695.17 KXH44759.1 - 0.0021 17.8 0.1 1.8 8.3 0.0 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_25 PF13481.6 KXH44759.1 - 0.0021 17.6 3.8 1.3 8.6 0.1 3.4 2 2 1 3 3 3 2 AAA domain Zeta_toxin PF06414.12 KXH44759.1 - 0.0035 16.6 1.6 0.6 9.4 0.0 2.7 3 0 0 3 3 2 1 Zeta toxin Mg_chelatase PF01078.21 KXH44759.1 - 0.0052 16.2 0.6 0.79 9.1 0.1 2.7 3 0 0 3 3 2 1 Magnesium chelatase, subunit ChlI Cytidylate_kin2 PF13189.6 KXH44759.1 - 0.0053 16.9 0.1 4.9 7.3 0.0 2.5 2 0 0 2 2 2 1 Cytidylate kinase-like family AAA_28 PF13521.6 KXH44759.1 - 0.0096 16.2 0.2 2.2 8.5 0.1 2.5 2 0 0 2 2 2 1 AAA domain SKI PF01202.22 KXH44759.1 - 0.0097 16.0 0.2 1.6 8.8 0.1 2.5 2 0 0 2 2 2 1 Shikimate kinase Sigma54_activat PF00158.26 KXH44759.1 - 0.014 15.1 0.2 1.1 8.9 0.0 2.9 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_17 PF13207.6 KXH44759.1 - 0.018 15.5 2.0 2.5 8.5 0.1 2.9 3 0 0 3 3 2 0 AAA domain Sigma54_activ_2 PF14532.6 KXH44759.1 - 0.019 15.1 0.0 1.2 9.2 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain Rad17 PF03215.15 KXH44759.1 - 0.036 14.0 0.0 4.5 7.2 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain ATPase PF06745.13 KXH44759.1 - 0.05 12.9 0.0 13 5.1 0.0 2.4 2 0 0 2 2 2 0 KaiC Viral_helicase1 PF01443.18 KXH44759.1 - 0.05 13.3 0.0 4.3 7.0 0.0 2.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_29 PF13555.6 KXH44759.1 - 0.05 13.3 0.0 0.89 9.3 0.1 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain ABC_tran PF00005.27 KXH44759.1 - 0.052 14.1 0.1 25 5.4 0.1 2.9 2 0 0 2 2 2 0 ABC transporter DUF2075 PF09848.9 KXH44759.1 - 0.078 12.2 0.0 9 5.4 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) SLX9 PF15341.6 KXH44759.1 - 0.12 12.8 1.7 0.24 11.8 0.8 1.9 2 0 0 2 2 1 0 Ribosome biogenesis protein SLX9 APS_kinase PF01583.20 KXH44759.1 - 0.15 11.9 0.3 0.9 9.4 0.0 2.3 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_3 PF07726.11 KXH44759.1 - 0.15 11.9 0.0 8.2 6.3 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MCM PF00493.23 KXH44760.1 - 3.9e-104 346.6 0.3 7.1e-104 345.8 0.0 1.5 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 KXH44760.1 - 4.1e-28 97.7 0.7 7e-28 97.0 0.7 1.3 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KXH44760.1 - 1.5e-20 73.4 0.3 3.2e-20 72.3 0.3 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KXH44760.1 - 4.4e-18 65.8 0.3 1.2e-17 64.4 0.3 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KXH44760.1 - 1.2e-07 31.4 0.0 1.4e-05 24.5 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KXH44760.1 - 4.2e-06 26.8 0.0 1.4e-05 25.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_lid_2 PF17863.1 KXH44760.1 - 0.0011 18.8 0.3 0.0034 17.2 0.3 1.8 1 0 0 1 1 1 1 AAA lid domain AAA_3 PF07726.11 KXH44760.1 - 0.015 15.2 0.0 0.05 13.5 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RecX PF02631.16 KXH44760.1 - 0.039 14.4 0.6 0.63 10.5 0.1 2.4 2 0 0 2 2 2 0 RecX family Mg_chelatase_C PF13335.6 KXH44760.1 - 0.072 13.7 1.7 0.28 11.9 0.2 2.6 2 1 1 3 3 3 0 Magnesium chelatase, subunit ChlI C-terminal Sigma54_activat PF00158.26 KXH44760.1 - 0.15 11.7 0.0 0.96 9.1 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain EcoR124_C PF12008.8 KXH44760.1 - 0.17 11.5 0.8 0.37 10.4 0.8 1.6 1 0 0 1 1 1 0 Type I restriction and modification enzyme - subunit R C terminal DAP3 PF10236.9 KXH44761.1 - 2.6e-91 306.0 0.0 3.4e-91 305.7 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 Glucosamine_iso PF01182.20 KXH44761.1 - 0.083 12.8 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase RRS1 PF04939.12 KXH44762.1 - 2.8e-58 196.4 6.6 3.2e-58 196.2 6.6 1.0 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) U1snRNP70_N PF12220.8 KXH44762.1 - 2.7 8.7 9.5 7.5 7.3 4.7 2.4 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RhoGAP PF00620.27 KXH44763.1 - 4.2e-28 98.1 0.0 8.7e-28 97.1 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain Prenyltrans PF00432.21 KXH44765.1 - 3.7e-54 180.1 11.2 1.3e-11 44.0 0.0 6.1 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 KXH44765.1 - 0.00076 18.7 0.0 0.22 10.6 0.0 3.4 2 1 2 4 4 4 2 Squalene-hopene cyclase N-terminal domain zf-C2H2_2 PF12756.7 KXH44766.1 - 0.058 13.7 0.0 0.14 12.5 0.0 1.6 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) MutS_V PF00488.21 KXH44767.1 - 1.9e-69 233.4 0.1 3.6e-69 232.6 0.1 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KXH44767.1 - 5.1e-34 118.2 1.7 1.6e-33 116.6 1.7 1.9 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 KXH44767.1 - 9.9e-29 99.9 0.0 2e-28 98.9 0.0 1.6 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 KXH44767.1 - 3.4e-11 43.6 0.0 1.4e-10 41.6 0.0 2.1 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.18 KXH44767.1 - 3.6e-05 24.0 0.0 9.8e-05 22.6 0.0 1.8 1 0 0 1 1 1 1 MutS family domain IV DUF4911 PF16256.5 KXH44767.1 - 0.0064 16.4 0.1 0.018 15.0 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4911) AAA_27 PF13514.6 KXH44767.1 - 0.044 13.4 0.0 0.19 11.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain ORC6 PF05460.13 KXH44767.1 - 0.071 12.4 8.3 0.13 11.5 8.3 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) AAA_29 PF13555.6 KXH44767.1 - 0.13 12.1 0.1 0.36 10.6 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Abhydrolase_3 PF07859.13 KXH44768.1 - 7e-43 146.9 0.0 8.9e-43 146.6 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KXH44768.1 - 3.4e-05 22.9 0.3 9.9e-05 21.4 0.3 1.6 1 1 0 1 1 1 1 Carboxylesterase family COX17 PF05051.13 KXH44769.1 - 7.4e-21 74.3 6.1 8.7e-21 74.0 6.1 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) G-patch PF01585.23 KXH44770.1 - 0.00019 21.2 0.0 0.00073 19.4 0.0 2.1 1 1 0 1 1 1 1 G-patch domain GREB1 PF15782.5 KXH44770.1 - 0.058 10.5 25.9 0.07 10.3 25.9 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer G-patch_2 PF12656.7 KXH44770.1 - 0.073 13.2 0.0 0.073 13.2 0.0 4.5 3 2 0 3 3 3 0 G-patch domain TFIIF_alpha PF05793.12 KXH44770.1 - 0.73 8.3 67.7 1.5 7.3 67.7 1.4 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Borrelia_P83 PF05262.11 KXH44770.1 - 1.9 6.9 42.2 2.6 6.4 42.2 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Mitofilin PF09731.9 KXH44770.1 - 2.3 6.9 47.9 3 6.6 47.9 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein AF-4 PF05110.13 KXH44770.1 - 5.6 4.9 52.9 6.9 4.6 52.9 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein PITH PF06201.13 KXH44776.1 - 2.9e-35 121.7 0.0 4.1e-35 121.2 0.0 1.2 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.20 KXH44776.1 - 8.8e-28 96.3 0.0 1.5e-27 95.6 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 KXH44776.1 - 3.6e-06 26.5 0.0 5.6e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 KXH44776.1 - 7.8e-06 26.1 0.0 0.00021 21.6 0.0 2.3 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_2 PF13098.6 KXH44776.1 - 1.6e-05 25.3 0.1 6.9e-05 23.3 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.21 KXH44776.1 - 0.0026 17.7 0.0 0.0078 16.1 0.0 1.8 2 0 0 2 2 2 1 AhpC/TSA family Thioredoxin_7 PF13899.6 KXH44776.1 - 0.003 17.7 0.0 0.0062 16.7 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.6 KXH44776.1 - 0.028 14.2 0.0 0.047 13.5 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Serglycin PF04360.12 KXH44776.1 - 0.06 13.3 0.7 0.11 12.4 0.7 1.4 1 0 0 1 1 1 0 Serglycin HyaE PF07449.11 KXH44776.1 - 0.09 12.7 0.0 0.24 11.4 0.0 1.7 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE DUF1207 PF06727.11 KXH44776.1 - 0.12 11.2 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1207) DivIC PF04977.15 KXH44780.1 - 0.01 15.6 1.5 0.018 14.8 1.5 1.3 1 0 0 1 1 1 0 Septum formation initiator GAS PF13851.6 KXH44780.1 - 0.015 14.6 0.2 0.023 14.0 0.2 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding HAP1_N PF04849.13 KXH44780.1 - 0.022 13.9 0.4 0.033 13.4 0.4 1.1 1 0 0 1 1 1 0 HAP1 N-terminal conserved region ZapB PF06005.12 KXH44780.1 - 0.024 15.1 1.3 0.043 14.3 1.3 1.3 1 0 0 1 1 1 0 Cell division protein ZapB APG6_N PF17675.1 KXH44780.1 - 0.031 14.8 0.7 0.047 14.2 0.7 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region Spc7 PF08317.11 KXH44780.1 - 0.04 12.8 0.4 0.058 12.3 0.4 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Myosin_tail_1 PF01576.19 KXH44780.1 - 0.068 11.0 0.1 0.087 10.6 0.1 1.0 1 0 0 1 1 1 0 Myosin tail Spc29 PF17082.5 KXH44780.1 - 0.096 12.5 0.1 0.15 11.9 0.1 1.2 1 0 0 1 1 1 0 Spindle Pole Component 29 FlaC_arch PF05377.11 KXH44780.1 - 0.18 12.2 0.8 0.4 11.1 0.8 1.5 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) ADH_zinc_N PF00107.26 KXH44781.1 - 1.7e-10 41.0 0.0 3.8e-10 39.8 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXH44781.1 - 0.0008 19.3 0.0 0.0026 17.6 0.0 2.0 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 KXH44781.1 - 0.033 13.6 0.1 0.056 12.9 0.1 1.3 1 0 0 1 1 1 0 short chain dehydrogenase eIF_4EBP PF05456.11 KXH44782.1 - 0.32 10.9 3.0 16 5.5 0.7 2.4 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) CorA PF01544.18 KXH44783.1 - 1.3e-16 60.8 4.2 1.4e-11 44.2 0.0 3.2 3 0 0 3 3 3 2 CorA-like Mg2+ transporter protein IHO1 PF15771.5 KXH44783.1 - 6.9 5.3 7.0 0.17 10.6 0.4 1.5 2 0 0 2 2 2 0 Interactor of HORMAD1 protein 1 Exo_endo_phos PF03372.23 KXH44785.1 - 6.3e-06 25.9 0.5 1.4e-05 24.8 0.5 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family HET PF06985.11 KXH44786.1 - 2.4e-27 96.1 3.7 5.8e-26 91.6 3.7 2.3 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SelR PF01641.18 KXH44788.1 - 4.6e-48 162.3 0.0 6e-48 161.9 0.0 1.1 1 0 0 1 1 1 1 SelR domain zinc_ribbon_10 PF10058.9 KXH44788.1 - 0.11 12.2 0.1 2.1 8.1 0.0 2.2 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein Yippee-Mis18 PF03226.14 KXH44788.1 - 0.12 12.6 0.2 0.28 11.4 0.2 1.6 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DZR PF12773.7 KXH44788.1 - 0.73 9.9 3.6 6.9 6.8 2.5 2.2 1 1 2 3 3 3 0 Double zinc ribbon zf-ribbon_3 PF13248.6 KXH44788.1 - 2.8 7.5 5.3 2.1 7.9 0.1 2.8 3 0 0 3 3 3 0 zinc-ribbon domain Glyoxalase PF00903.25 KXH44789.1 - 2.2e-38 131.4 0.2 4.7e-18 65.6 0.0 2.3 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KXH44789.1 - 9.5e-17 61.3 0.1 1.4e-07 31.8 0.0 3.5 2 2 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 KXH44789.1 - 5e-07 30.0 0.0 0.024 14.8 0.0 3.6 2 2 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_2 PF12681.7 KXH44789.1 - 6.4e-06 26.1 2.6 0.068 13.1 0.3 4.4 3 2 0 3 3 3 1 Glyoxalase-like domain Glyoxalase_6 PF18029.1 KXH44789.1 - 1.8e-05 25.5 0.0 0.11 13.3 0.0 2.9 2 1 1 3 3 3 2 Glyoxalase-like domain DUF1338 PF07063.13 KXH44789.1 - 0.00018 20.8 0.0 0.16 11.1 0.0 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF1338) CppA_N PF14506.6 KXH44789.1 - 0.00024 21.2 0.0 0.16 12.1 0.0 2.5 2 0 0 2 2 2 2 CppA N-terminal Pfk_N PF18468.1 KXH44789.1 - 0.0019 18.6 0.4 0.64 10.5 0.0 2.5 2 0 0 2 2 2 2 Phosphofructokinase N-terminal domain yeast MoaF PF10703.9 KXH44789.1 - 0.016 15.2 0.0 2.8 7.9 0.0 2.4 2 0 0 2 2 2 0 MoaF N-terminal domain GCD14_N PF14801.6 KXH44789.1 - 0.17 11.8 0.0 3.1 7.7 0.0 2.5 2 0 0 2 2 2 0 tRNA methyltransferase complex GCD14 subunit N-term Piwi PF02171.17 KXH44790.1 - 7e-71 238.9 0.0 1.1e-70 238.3 0.0 1.2 1 0 0 1 1 1 1 Piwi domain ArgoL1 PF08699.10 KXH44790.1 - 4.4e-11 42.3 0.2 1.1e-10 41.0 0.2 1.7 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoN PF16486.5 KXH44790.1 - 1.6e-07 32.1 0.0 3.2e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL2 PF16488.5 KXH44790.1 - 5.1e-07 29.9 0.0 1.2e-06 28.8 0.0 1.6 1 0 0 1 1 1 1 Argonaute linker 2 domain ArgoMid PF16487.5 KXH44790.1 - 0.00016 21.9 0.0 0.00044 20.4 0.0 1.8 1 0 0 1 1 1 1 Mid domain of argonaute Inv-AAD PF18785.1 KXH44791.1 - 5.5e-60 200.9 0.2 6.4e-60 200.7 0.2 1.0 1 0 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase dCMP_cyt_deam_1 PF00383.23 KXH44791.1 - 7.2e-14 51.5 0.0 1e-13 51.0 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.11 KXH44791.1 - 0.00014 21.8 0.0 0.00016 21.6 0.0 1.2 1 0 0 1 1 1 1 APOBEC-like N-terminal domain SNAD4 PF18750.1 KXH44791.1 - 0.17 12.0 0.0 0.22 11.7 0.0 1.2 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 DnaJ PF00226.31 KXH44792.1 - 8e-23 80.4 2.0 2.4e-22 78.8 2.0 1.9 1 0 0 1 1 1 1 DnaJ domain Nif11 PF07862.11 KXH44792.1 - 0.0009 19.5 2.6 0.76 10.1 0.0 3.9 3 1 0 3 3 3 1 Nif11 domain DUF325 PF03804.13 KXH44792.1 - 0.092 12.8 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Viral proteins of unknown function Stn1 PF10451.9 KXH44793.1 - 4.3e-13 48.8 2.1 3.2e-06 26.3 0.0 2.2 2 0 0 2 2 2 2 Telomere regulation protein Stn1 TAF4 PF05236.14 KXH44793.1 - 0.16 11.7 9.0 0.22 11.3 9.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family MCM_bind PF09739.9 KXH44793.1 - 0.45 8.9 2.9 0.63 8.4 2.9 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Rrn6 PF10214.9 KXH44793.1 - 0.63 8.5 4.6 7.2 5.0 5.5 1.9 2 0 0 2 2 2 0 RNA polymerase I-specific transcription-initiation factor US30 PF17624.2 KXH44793.1 - 2.8 6.9 5.5 6.2 5.8 1.2 2.2 1 1 1 2 2 2 0 Family of unknown function Glyco_hydro81C PF17652.1 KXH44794.1 - 8.2e-161 535.1 5.8 1e-160 534.7 5.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 KXH44794.1 - 7.1e-120 400.0 1.5 7.1e-120 400.0 1.5 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 81 N-terminal domain Na_Ca_ex PF01699.24 KXH44795.1 - 5.5e-46 156.3 34.5 5.8e-25 88.0 14.5 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Utp14 PF04615.13 KXH44796.1 - 4.4e-193 643.9 76.2 4.4e-193 643.9 76.2 2.1 1 1 1 2 2 2 1 Utp14 protein COX15-CtaA PF02628.15 KXH44797.1 - 5.7e-111 370.7 6.7 7.3e-111 370.3 6.7 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein tRNA-synt_2 PF00152.20 KXH44798.1 - 1.9e-74 250.6 0.6 2.6e-74 250.1 0.6 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.20 KXH44798.1 - 2e-05 24.2 0.4 0.067 12.7 0.1 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA_anti-codon PF01336.25 KXH44798.1 - 0.0079 16.2 0.0 0.025 14.5 0.0 2.0 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DUF3921 PF13060.6 KXH44799.1 - 0.055 13.5 0.6 0.34 11.0 0.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3921) Peptidase_S58 PF03576.14 KXH44800.1 - 1.4e-114 382.7 0.8 1.6e-114 382.5 0.8 1.0 1 0 0 1 1 1 1 Peptidase family S58 Fe-ADH PF00465.19 KXH44801.1 - 3.8e-100 335.3 0.0 4.7e-100 334.9 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 KXH44801.1 - 7.5e-13 48.7 0.0 4.5e-10 39.7 0.0 2.3 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Peripla_BP_6 PF13458.6 KXH44801.1 - 0.0052 16.5 0.1 0.0092 15.7 0.1 1.3 1 0 0 1 1 1 1 Periplasmic binding protein Deltaretro_Tax PF05599.11 KXH44801.1 - 0.2 12.2 3.5 0.8 10.3 2.1 2.4 2 0 0 2 2 2 0 Deltaretrovirus Tax protein 2OG-FeII_Oxy_2 PF13532.6 KXH44802.1 - 4.4e-30 105.3 0.0 6.6e-30 104.8 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Pkinase PF00069.25 KXH44803.1 - 2.1e-69 233.8 0.0 2.8e-69 233.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXH44803.1 - 5.5e-30 104.5 0.0 7.2e-30 104.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXH44803.1 - 0.0019 17.6 0.0 0.003 16.9 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KXH44803.1 - 0.0021 17.0 0.0 0.015 14.3 0.0 1.9 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 KXH44803.1 - 0.0034 17.3 0.0 0.0053 16.7 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KXH44803.1 - 0.029 13.4 0.0 0.043 12.9 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Cyclin_C PF02984.19 KXH44840.1 - 2.7e-11 43.6 0.2 5.1e-11 42.7 0.2 1.4 1 0 0 1 1 1 1 Cyclin, C-terminal domain Cyclin_N PF00134.23 KXH44840.1 - 7.2e-11 41.9 0.1 1.3e-10 41.1 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain SDA1 PF05285.12 KXH44840.1 - 0.055 12.9 25.4 0.079 12.4 25.4 1.2 1 0 0 1 1 1 0 SDA1 DUF913 PF06025.12 KXH44840.1 - 0.11 11.4 0.4 0.16 10.9 0.4 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) SAPS PF04499.15 KXH44840.1 - 0.23 10.2 3.2 0.29 9.9 3.2 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Nop14 PF04147.12 KXH44840.1 - 0.44 8.7 26.9 0.62 8.2 26.9 1.1 1 0 0 1 1 1 0 Nop14-like family PPP4R2 PF09184.11 KXH44840.1 - 0.46 10.0 18.8 0.71 9.4 18.8 1.3 1 0 0 1 1 1 0 PPP4R2 CDC45 PF02724.14 KXH44840.1 - 0.48 8.7 20.7 0.67 8.2 20.7 1.1 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 KXH44840.1 - 1.2 7.2 38.3 1.7 6.6 38.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi TFIIA PF03153.13 KXH44840.1 - 1.3 8.9 19.9 1.6 8.7 19.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Utp14 PF04615.13 KXH44840.1 - 3.5 6.1 14.8 5 5.6 14.8 1.2 1 0 0 1 1 1 0 Utp14 protein Mpp10 PF04006.12 KXH44840.1 - 8.1 4.8 24.6 12 4.1 24.6 1.2 1 0 0 1 1 1 0 Mpp10 protein DUF2457 PF10446.9 KXH44840.1 - 9.1 5.3 43.2 14 4.7 43.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Perilipin PF03036.16 KXH44841.1 - 0.018 14.1 0.3 0.026 13.6 0.3 1.2 1 0 0 1 1 1 0 Perilipin family Cyclin_N PF00134.23 KXH44842.1 - 1.7e-17 63.3 0.0 2.4e-17 62.9 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain UDPG_MGDP_dh PF00984.19 KXH44860.1 - 4.9e-19 68.3 0.0 1.1e-18 67.2 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_N PF03721.14 KXH44860.1 - 2.8e-16 59.6 0.1 1.2e-13 51.1 0.1 2.2 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_2 PF03446.15 KXH44860.1 - 1.5e-06 28.5 0.0 2.6e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase UDPG_MGDP_dh_C PF03720.15 KXH44860.1 - 0.005 17.3 0.0 0.0097 16.3 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain TrkA_N PF02254.18 KXH44860.1 - 0.15 12.4 0.0 0.31 11.3 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Polysacc_deac_1 PF01522.21 KXH44862.1 - 5.3e-25 87.7 0.0 9.8e-25 86.9 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.19 KXH44862.1 - 5.3e-16 58.8 84.0 1.2e-06 28.9 16.2 3.9 3 1 1 4 4 4 3 Chitin recognition protein DUF2334 PF10096.9 KXH44862.1 - 0.0048 16.6 0.0 0.0087 15.7 0.0 1.3 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) Med3 PF11593.8 KXH44862.1 - 1.4 8.1 10.5 2.1 7.4 10.5 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Chitin_synth_2 PF03142.15 KXH44863.1 - 6e-43 147.3 3.9 6e-33 114.3 0.9 2.4 2 1 0 2 2 2 2 Chitin synthase Glycos_transf_2 PF00535.26 KXH44863.1 - 1.9e-07 31.1 0.0 0.01 15.7 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.6 KXH44863.1 - 0.0002 21.3 11.7 0.0004 20.4 5.8 3.2 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KXH44863.1 - 0.00068 19.6 0.0 2.3 8.1 0.0 3.0 3 0 0 3 3 3 2 Glycosyltransferase like family 2 Polysacc_deac_1 PF01522.21 KXH44864.1 - 7.7e-29 100.1 0.0 1.3e-28 99.4 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.19 KXH44864.1 - 2e-23 82.6 70.8 3e-09 37.2 20.8 3.7 3 1 0 3 3 3 3 Chitin recognition protein DUF2334 PF10096.9 KXH44864.1 - 0.014 15.0 0.1 0.02 14.6 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) Glyco_hydro_57 PF03065.15 KXH44864.1 - 0.028 13.6 0.0 0.088 12.0 0.0 1.8 1 1 1 2 2 2 0 Glycosyl hydrolase family 57 Tyrosinase PF00264.20 KXH44866.1 - 5e-42 144.7 1.8 8.1e-42 144.0 1.8 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase DUF3224 PF11528.8 KXH44866.1 - 0.12 12.2 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3224) 4HBT_3 PF13622.6 KXH44867.1 - 5.2e-53 180.8 0.0 6.1e-53 180.6 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 KXH44867.1 - 0.0051 16.7 0.0 0.0083 16.0 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA thioesterase Aa_trans PF01490.18 KXH44868.1 - 3.5e-49 167.6 38.1 4e-49 167.4 38.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein ADH_zinc_N_2 PF13602.6 KXH44869.1 - 3.1e-10 41.2 0.0 7.3e-10 40.0 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXH44869.1 - 7.1e-07 29.1 0.2 2.7e-06 27.2 0.2 1.9 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain MFS_1 PF07690.16 KXH44870.1 - 6.2e-33 114.2 14.9 6.2e-33 114.2 14.9 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH44870.1 - 5.6e-06 25.5 4.2 1.2e-05 24.4 4.2 1.5 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH44871.1 - 2.4e-20 72.8 56.3 6e-19 68.2 30.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH44871.1 - 0.00011 21.3 31.2 0.0006 18.8 1.0 3.2 3 0 0 3 3 3 2 Sugar (and other) transporter TssN PF17555.2 KXH44871.1 - 0.014 14.8 0.4 0.014 14.8 0.4 2.0 2 0 0 2 2 2 0 Type VI secretion system, TssN Peptidase_M56 PF05569.11 KXH44871.1 - 0.047 12.9 0.5 0.71 9.0 0.0 2.4 2 0 0 2 2 2 0 BlaR1 peptidase M56 Pro_racemase PF05544.11 KXH44872.1 - 3.1e-66 223.7 0.0 3.8e-66 223.4 0.0 1.0 1 0 0 1 1 1 1 Proline racemase Glucan_synthase PF02364.15 KXH44872.1 - 0.13 10.3 0.0 0.18 10.0 0.0 1.1 1 0 0 1 1 1 0 1,3-beta-glucan synthase component Fungal_trans_2 PF11951.8 KXH44873.1 - 1.3e-35 123.0 9.2 1.8e-35 122.5 9.2 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain TENA_THI-4 PF03070.16 KXH44873.1 - 0.052 13.4 0.1 0.41 10.4 0.0 2.4 3 0 0 3 3 3 0 TENA/THI-4/PQQC family Cu_amine_oxid PF01179.20 KXH44874.1 - 1.1e-160 535.1 0.0 1.7e-160 534.5 0.0 1.3 2 0 0 2 2 2 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.16 KXH44874.1 - 4.3e-08 33.3 0.0 1e-07 32.1 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.16 KXH44874.1 - 2.4e-05 24.7 0.0 4.9e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Acyl_transf_3 PF01757.22 KXH44875.1 - 4.8e-24 85.1 34.5 4.8e-24 85.1 34.5 1.4 2 0 0 2 2 2 1 Acyltransferase family HTH_40 PF14493.6 KXH44878.1 - 0.1 13.0 0.1 0.13 12.7 0.1 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain DUF3716 PF12511.8 KXH44879.1 - 2.3e-07 30.8 8.7 3.9e-07 30.0 8.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) Chs7 PF12271.8 KXH44880.1 - 2.9e-114 381.3 22.9 3.3e-111 371.3 19.5 2.0 2 0 0 2 2 2 2 Chitin synthase export chaperone Cytomega_TRL10 PF06084.11 KXH44880.1 - 0.033 14.2 0.1 0.41 10.6 0.0 2.2 2 0 0 2 2 2 0 Cytomegalovirus TRL10 protein DUF3382 PF11862.8 KXH44880.1 - 0.17 12.2 5.4 0.066 13.5 2.0 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF3382) SGTA_dimer PF16546.5 KXH44881.1 - 0.08 12.7 0.3 0.33 10.8 0.1 2.1 2 0 0 2 2 2 0 Homodimerisation domain of SGTA Cyclin PF08613.11 KXH44882.1 - 1.5e-12 48.2 0.0 3.6e-12 46.9 0.0 1.8 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 KXH44882.1 - 0.00054 19.7 0.0 0.00085 19.1 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Peptidase_S8 PF00082.22 KXH44884.1 - 5.2e-43 147.4 0.0 1.5e-42 145.9 0.0 1.6 1 1 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 KXH44884.1 - 4.8e-11 43.4 0.0 1.1e-10 42.2 0.0 1.7 1 0 0 1 1 1 1 Fn3-like domain PA PF02225.22 KXH44884.1 - 3e-08 33.6 0.2 9.2e-08 32.0 0.2 1.9 1 0 0 1 1 1 1 PA domain RPT PF13446.6 KXH44884.1 - 0.058 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 A repeated domain in UCH-protein COesterase PF00135.28 KXH44885.1 - 4.2e-89 299.8 0.0 1.4e-88 298.1 0.0 1.6 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXH44885.1 - 0.0001 22.3 0.1 0.00039 20.3 0.1 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold BolA PF01722.18 KXH44886.1 - 6.9e-11 42.3 0.0 1.7e-10 41.0 0.0 1.6 1 1 0 1 1 1 1 BolA-like protein p450 PF00067.22 KXH44887.1 - 1.9e-49 168.7 0.0 2.7e-49 168.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 HET PF06985.11 KXH44888.1 - 1.7e-30 106.3 0.2 3.2e-30 105.4 0.2 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SMP_LBD PF17047.5 KXH44889.1 - 4.8e-22 78.3 0.1 7e-22 77.8 0.1 1.2 1 0 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain C2 PF00168.30 KXH44889.1 - 7.2e-18 64.8 0.0 1.9e-12 47.3 0.0 2.3 2 0 0 2 2 2 2 C2 domain EHN PF06441.12 KXH44890.1 - 2e-25 89.3 0.3 3.3e-25 88.6 0.3 1.4 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 KXH44890.1 - 1.4e-06 28.1 0.0 2.8e-06 27.2 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXH44890.1 - 6.7e-05 23.6 2.0 0.00023 21.8 2.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Tyrosinase PF00264.20 KXH44892.1 - 4e-53 181.0 0.0 5.5e-53 180.5 0.0 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase Asp-Al_Ex PF06826.12 KXH44893.1 - 8.3 6.2 14.1 2.9 7.7 3.0 2.6 1 1 1 2 2 2 0 Predicted Permease Membrane Region ADC PF06314.11 KXH44894.1 - 1.7e-36 125.9 0.0 2e-36 125.7 0.0 1.0 1 0 0 1 1 1 1 Acetoacetate decarboxylase (ADC) ADH_zinc_N PF00107.26 KXH44895.1 - 5.5e-18 65.2 0.2 9.7e-18 64.4 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXH44895.1 - 2.2e-17 62.9 2.1 2.4e-16 59.6 0.1 2.7 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KXH44895.1 - 1.1e-07 33.0 0.1 3.6e-07 31.3 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase NAD_binding_2 PF03446.15 KXH44895.1 - 0.0084 16.3 0.1 0.013 15.7 0.1 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Mur_ligase PF01225.25 KXH44895.1 - 0.037 14.4 0.4 0.069 13.5 0.4 1.5 1 0 0 1 1 1 0 Mur ligase family, catalytic domain UDPG_MGDP_dh_N PF03721.14 KXH44895.1 - 0.14 11.7 0.1 0.28 10.7 0.1 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_31 PF13847.6 KXH44895.1 - 0.18 11.6 0.3 0.62 9.8 0.2 1.7 1 1 1 2 2 2 0 Methyltransferase domain 2-Hacid_dh_C PF02826.19 KXH44895.1 - 0.2 11.0 0.7 0.34 10.2 0.4 1.4 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GATase PF00117.28 KXH44897.1 - 1.5e-05 24.8 0.0 2.1e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I zf-RING_5 PF14634.6 KXH44898.1 - 1.5e-06 28.0 5.5 1.5e-06 28.0 5.5 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KXH44898.1 - 5.8e-05 23.0 4.2 0.00013 21.9 4.2 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KXH44898.1 - 0.00061 19.6 7.8 0.00061 19.6 7.8 2.2 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KXH44898.1 - 0.0029 17.4 7.0 0.014 15.3 6.9 2.0 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KXH44898.1 - 0.0031 17.8 5.3 0.0031 17.8 5.3 2.4 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.6 KXH44898.1 - 0.0096 15.7 1.6 0.0096 15.7 1.6 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KXH44898.1 - 0.019 15.1 2.3 0.019 15.1 2.3 2.6 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 KXH44898.1 - 0.039 14.3 3.1 0.091 13.1 3.1 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain FYVE PF01363.21 KXH44898.1 - 1.5 9.0 9.6 3.1 8.0 9.6 1.6 1 1 0 1 1 1 0 FYVE zinc finger Phage_holin_2_4 PF16082.5 KXH44900.1 - 0.074 12.8 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like Glyco_hydro_28 PF00295.17 KXH44901.1 - 2.2e-46 158.4 4.7 3.2e-46 157.9 4.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.6 KXH44901.1 - 0.12 12.3 7.7 0.071 13.0 5.6 1.7 1 1 0 1 1 1 0 Right handed beta helix region PhoD PF09423.10 KXH44901.1 - 0.17 10.9 0.0 0.25 10.3 0.0 1.2 1 0 0 1 1 1 0 PhoD-like phosphatase Peptidase_S8 PF00082.22 KXH44903.1 - 1.5e-43 149.2 3.0 2.4e-43 148.5 3.0 1.3 1 0 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 KXH44903.1 - 4.6e-10 40.2 0.0 1.1e-09 39.0 0.0 1.6 1 0 0 1 1 1 1 Fn3-like domain G5 PF07501.12 KXH44903.1 - 0.23 11.9 0.6 0.47 10.9 0.2 1.8 2 0 0 2 2 2 0 G5 domain DUF4267 PF14087.6 KXH44904.1 - 8.7e-21 74.1 3.6 9.9e-21 73.9 3.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) TPP_enzyme_N PF02776.18 KXH44906.1 - 1e-39 135.9 0.0 7.3e-38 129.9 0.0 2.4 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KXH44906.1 - 2e-24 86.1 0.0 6.2e-24 84.5 0.0 1.9 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KXH44906.1 - 3.9e-13 49.3 0.0 1.4e-12 47.5 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Cyclin PF08613.11 KXH44908.1 - 8.7e-43 146.5 0.0 2e-42 145.3 0.0 1.5 1 1 0 1 1 1 1 Cyclin CFEM PF05730.11 KXH44920.1 - 0.00011 22.2 2.8 0.00011 22.2 2.8 2.9 2 0 0 2 2 2 1 CFEM domain bVLRF1 PF18826.1 KXH44921.1 - 1.3e-62 210.0 0.1 2.3e-62 209.3 0.1 1.4 1 0 0 1 1 1 1 bacteroidetes VLRF1 release factor Ank_5 PF13857.6 KXH44921.1 - 4.3e-07 30.1 0.0 1.1e-06 28.7 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Casein PF00363.18 KXH44921.1 - 0.12 12.8 0.3 0.25 11.8 0.3 1.5 1 0 0 1 1 1 0 Casein Ank PF00023.30 KXH44921.1 - 0.2 12.2 0.4 0.48 11.0 0.4 1.7 1 0 0 1 1 1 0 Ankyrin repeat RPA43_OB PF17875.1 KXH44921.1 - 5 7.8 6.9 5.8 7.5 2.4 2.9 3 0 0 3 3 3 0 RPA43 OB domain in RNA Pol I MT0933_antitox PF14013.6 KXH44922.1 - 0.0034 17.7 5.5 0.0053 17.0 4.1 2.1 2 1 0 2 2 2 1 MT0933-like antitoxin protein CENP-F_N PF10481.9 KXH44923.1 - 0.052 13.2 0.7 0.081 12.6 0.7 1.2 1 0 0 1 1 1 0 Cenp-F N-terminal domain Lactamase_B_3 PF13483.6 KXH44930.1 - 1.3e-08 34.9 0.0 5.4e-07 29.7 0.0 2.1 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 KXH44930.1 - 2.3e-07 30.5 0.0 3.6e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KXH44930.1 - 6.5e-06 26.3 0.2 1e-05 25.7 0.2 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily FAD_binding_3 PF01494.19 KXH44931.1 - 5.6e-11 42.3 2.2 7.2e-07 28.8 0.0 3.0 2 1 0 2 2 2 2 FAD binding domain NAD_binding_9 PF13454.6 KXH44931.1 - 0.00012 22.1 0.0 0.0002 21.4 0.0 1.4 1 0 0 1 1 1 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KXH44931.1 - 0.00015 21.9 0.0 0.00035 20.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXH44931.1 - 0.00071 19.3 0.0 0.00088 19.0 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 KXH44931.1 - 0.044 12.9 0.0 0.064 12.4 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Aldo_ket_red PF00248.21 KXH44932.1 - 1.9e-30 106.1 0.0 4.3e-30 104.9 0.0 1.5 1 1 0 1 1 1 1 Aldo/keto reductase family p450 PF00067.22 KXH44933.1 - 1.7e-57 195.2 0.0 2.5e-57 194.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_3 PF01494.19 KXH44934.1 - 1.6e-28 100.0 0.0 2.7e-27 96.0 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.14 KXH44934.1 - 0.00032 19.7 0.5 0.011 14.7 0.3 2.1 2 0 0 2 2 2 1 Tryptophan halogenase NAD_binding_8 PF13450.6 KXH44934.1 - 0.00052 20.2 1.0 0.0013 19.0 1.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KXH44934.1 - 0.0013 17.9 0.6 0.0065 15.6 0.9 1.9 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 KXH44934.1 - 0.088 12.4 3.6 0.17 11.5 1.8 2.1 2 1 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXH44934.1 - 0.12 11.6 0.1 0.16 11.2 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Megourin PF17560.2 KXH44936.1 - 0.21 11.8 3.5 0.41 10.9 3.5 1.5 1 0 0 1 1 1 0 Aphid Megourins Abhydrolase_1 PF00561.20 KXH44937.1 - 4.9e-19 69.0 0.1 1.4e-16 60.9 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 KXH44937.1 - 2.9e-14 53.0 0.0 6.3e-14 51.9 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein Sugar_tr PF00083.24 KXH44938.1 - 2.6e-79 267.2 21.4 2.9e-79 267.0 21.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH44938.1 - 2.4e-14 53.1 42.2 2.4e-14 53.0 15.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Amidohydro_2 PF04909.14 KXH44939.1 - 5e-29 102.0 0.3 6.4e-29 101.7 0.3 1.1 1 0 0 1 1 1 1 Amidohydrolase Mito_carr PF00153.27 KXH44940.1 - 1e-55 185.6 6.7 7.3e-21 73.9 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Fungal_trans PF04082.18 KXH44941.1 - 4.4e-22 78.4 0.3 7.9e-22 77.5 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain PGF-CTERM PF18204.1 KXH44942.1 - 0.35 10.9 4.6 0.74 9.9 4.6 1.6 1 0 0 1 1 1 0 PGF-CTERM motif DUF805 PF05656.14 KXH44943.1 - 0.0014 19.0 1.4 0.0023 18.3 1.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF805) DHHC PF01529.20 KXH44943.1 - 0.4 10.8 4.5 2.4 8.3 0.6 2.2 2 0 0 2 2 2 0 DHHC palmitoyltransferase CD47 PF04549.14 KXH44944.1 - 0.048 13.9 4.0 1.7 8.8 0.7 2.1 2 0 0 2 2 2 0 CD47 transmembrane region DUF4383 PF14325.6 KXH44944.1 - 0.061 13.6 1.6 0.09 13.1 1.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4383) Glyco_hydro_12 PF01670.16 KXH44945.1 - 2e-46 158.7 2.1 2.3e-46 158.5 2.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 Transferase PF02458.15 KXH44948.1 - 1.1e-12 47.3 0.0 2.5e-12 46.2 0.0 1.5 1 1 0 1 1 1 1 Transferase family Mito_carr PF00153.27 KXH44949.1 - 5.9e-53 176.8 4.7 1.7e-18 66.3 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Phage_Coat_B PF05356.11 KXH44949.1 - 0.032 14.1 0.6 2.5 8.0 0.0 3.1 3 0 0 3 3 3 0 Phage Coat protein B HET PF06985.11 KXH44950.1 - 9.1e-25 87.7 0.1 1.5e-24 87.0 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) FA_hydroxylase PF04116.13 KXH44951.1 - 0.00019 21.8 0.0 0.00032 21.0 0.0 1.4 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily p450 PF00067.22 KXH44952.1 - 6e-60 203.3 0.0 8.3e-60 202.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 KdgT PF03812.13 KXH44952.1 - 0.036 13.4 1.6 0.053 12.8 1.6 1.2 1 0 0 1 1 1 0 2-keto-3-deoxygluconate permease DIOX_N PF14226.6 KXH44953.1 - 3.7e-20 72.9 0.0 5.7e-20 72.2 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KXH44953.1 - 9.5e-19 67.8 0.0 1.6e-18 67.0 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Transp_cyt_pur PF02133.15 KXH44954.1 - 1.6e-92 310.6 29.6 1.8e-92 310.4 29.6 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF983 PF06170.12 KXH44954.1 - 8 6.9 14.3 0.087 13.2 2.2 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF983) Asp_Glu_race PF01177.22 KXH44955.1 - 2.9e-09 37.1 0.0 1e-08 35.4 0.0 1.7 1 1 0 1 1 1 1 Asp/Glu/Hydantoin racemase Zn_clus PF00172.18 KXH44956.1 - 0.00015 21.8 6.4 0.00047 20.2 6.4 1.9 1 1 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXH44956.1 - 0.0044 16.1 0.2 0.0062 15.6 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain PepSY_TM PF03929.16 KXH44957.1 - 0.2 11.3 0.0 0.23 11.1 0.0 1.1 1 0 0 1 1 1 0 PepSY-associated TM region Tyrosinase PF00264.20 KXH44959.1 - 1.1e-18 68.3 0.4 1.3e-18 68.1 0.4 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase UPF0020 PF01170.18 KXH44975.1 - 0.072 12.8 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 CALM_bind PF16025.5 KXH44975.1 - 0.16 12.4 3.8 0.3 11.6 3.8 1.4 1 0 0 1 1 1 0 Calcium-dependent calmodulin binding AhpC-TSA PF00578.21 KXH44976.1 - 2e-06 27.7 0.0 3.9e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family AhpC-TSA_2 PF13911.6 KXH44976.1 - 3.5e-05 23.9 0.0 7e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme Redoxin PF08534.10 KXH44976.1 - 0.0012 18.5 0.0 0.0021 17.8 0.0 1.3 1 0 0 1 1 1 1 Redoxin PAP_assoc PF03828.19 KXH44978.1 - 4.3e-17 62.1 0.1 1.1e-16 60.8 0.1 1.8 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 KXH44978.1 - 3.1e-05 24.2 0.0 5.7e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain DUF2417 PF10329.9 KXH45204.1 - 5.5e-83 278.0 3.8 7.1e-83 277.6 3.8 1.1 1 0 0 1 1 1 1 Region of unknown function (DUF2417) HTH_35 PF13693.6 KXH45204.1 - 0.11 12.5 0.0 0.46 10.6 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding DUF2070 PF09843.9 KXH45204.1 - 0.28 9.4 11.6 0.39 9.0 11.6 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Oxysterol_BP PF01237.18 KXH45207.1 - 8.1e-89 298.0 0.1 3.2e-78 263.2 0.0 2.0 1 1 1 2 2 2 2 Oxysterol-binding protein zf-CCCH PF00642.24 KXH45208.1 - 1.2e-08 34.6 18.6 5.3e-07 29.4 2.6 3.2 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 KXH45208.1 - 0.0058 17.3 3.1 0.4 11.4 0.2 2.4 2 0 0 2 2 2 2 Torus domain zf_CCCH_4 PF18345.1 KXH45208.1 - 0.012 15.6 2.9 0.012 15.6 2.9 3.3 3 0 0 3 3 3 0 Zinc finger domain RRM_1 PF00076.22 KXH45208.1 - 0.014 15.2 0.0 0.021 14.6 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH_3 PF15663.5 KXH45208.1 - 0.057 13.6 1.8 0.37 11.0 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger containing family ELMO_CED12 PF04727.13 KXH45209.1 - 3.8e-49 167.2 0.0 1.1e-48 165.7 0.0 1.7 2 0 0 2 2 2 1 ELMO/CED-12 family PH_12 PF16457.5 KXH45209.1 - 2.6e-41 141.3 0.1 5.2e-41 140.3 0.1 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain DUF3361 PF11841.8 KXH45209.1 - 4.5e-13 49.4 0.1 1.5e-12 47.7 0.0 2.0 2 1 0 2 2 2 1 Domain of unknown function (DUF3361) Pirin PF02678.16 KXH45210.1 - 1.1e-28 99.4 0.1 3.5e-28 97.7 0.1 1.9 2 0 0 2 2 2 1 Pirin Pirin_C PF05726.13 KXH45210.1 - 3.1e-25 88.5 0.1 2.6e-24 85.6 0.1 2.0 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.11 KXH45210.1 - 2e-07 30.6 2.6 4e-05 23.2 1.3 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 KXH45210.1 - 0.012 15.3 0.2 0.41 10.4 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF861) zf-GRF PF06839.12 KXH45211.1 - 1.4e-09 37.8 8.4 2.9e-09 36.9 8.4 1.5 1 0 0 1 1 1 1 GRF zinc finger TMF_DNA_bd PF12329.8 KXH45211.1 - 0.0017 18.3 0.4 0.0035 17.3 0.4 1.5 1 0 0 1 1 1 1 TATA element modulatory factor 1 DNA binding PKcGMP_CC PF16808.5 KXH45211.1 - 0.0028 17.5 0.4 0.0054 16.6 0.4 1.5 1 0 0 1 1 1 1 Coiled-coil N-terminus of cGMP-dependent protein kinase ATG16 PF08614.11 KXH45211.1 - 0.051 13.8 0.1 0.051 13.8 0.1 1.9 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Csm1_N PF18504.1 KXH45211.1 - 0.13 12.7 1.0 0.24 11.7 1.0 1.4 1 0 0 1 1 1 0 Csm1 N-terminal domain DUF3818 PF12825.7 KXH45212.1 - 2.8e-130 434.3 4.1 4.4e-130 433.6 4.1 1.3 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 KXH45212.1 - 9.1e-40 135.7 1.5 1.1e-39 135.4 0.5 1.7 2 0 0 2 2 2 1 PX-associated PX PF00787.24 KXH45212.1 - 2.2e-16 59.8 0.0 1.4e-15 57.2 0.0 2.4 2 1 0 2 2 2 1 PX domain Cwf_Cwc_15 PF04889.12 KXH45212.1 - 0.027 14.2 4.6 0.077 12.7 4.6 1.7 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Myc_N PF01056.18 KXH45212.1 - 0.04 13.8 0.4 0.094 12.6 0.4 1.6 1 0 0 1 1 1 0 Myc amino-terminal region DUF3802 PF12290.8 KXH45212.1 - 0.15 12.5 1.0 0.57 10.7 1.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3802) DUF465 PF04325.13 KXH45212.1 - 1.4 9.0 6.3 13 6.0 0.2 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF465) PCAF_N PF06466.11 KXH45212.1 - 1.5 8.3 4.3 4.4 6.8 0.1 2.6 3 0 0 3 3 3 0 PCAF (P300/CBP-associated factor) N-terminal domain SASRP1 PF15160.6 KXH45213.1 - 0.041 13.6 0.0 0.096 12.3 0.0 1.6 1 0 0 1 1 1 0 Spermatogenesis-associated serine-rich protein 1 DotU PF09850.9 KXH45213.1 - 0.12 12.1 1.3 0.4 10.4 0.1 2.3 2 0 0 2 2 2 0 Type VI secretion system protein DotU Fib_alpha PF08702.10 KXH45213.1 - 0.19 11.9 0.1 2.4 8.3 0.1 2.3 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family NADH_Oxid_Nqo15 PF11497.8 KXH45213.1 - 0.48 10.5 3.5 1.6 8.8 0.4 2.3 2 0 0 2 2 2 0 NADH-quinone oxidoreductase chain 15 ATF7IP_BD PF16788.5 KXH45213.1 - 3.5 7.7 7.3 0.61 10.1 3.3 1.6 2 0 0 2 2 2 0 ATF-interacting protein binding domain SelP_N PF04592.14 KXH45213.1 - 5.1 6.4 8.9 2.5 7.4 2.4 2.2 2 0 0 2 2 2 0 Selenoprotein P, N terminal region Cgr1 PF03879.14 KXH45214.1 - 5.3e-35 120.1 31.7 6.1e-35 119.9 31.7 1.0 1 0 0 1 1 1 1 Cgr1 family Prismane PF03063.20 KXH45214.1 - 0.6 8.7 5.9 0.68 8.6 5.9 1.1 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family DUF429 PF04250.13 KXH45214.1 - 2.4 7.9 7.5 1.2 8.9 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF429) RR_TM4-6 PF06459.12 KXH45214.1 - 2.9 7.6 16.3 3.1 7.6 16.3 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 ATG101 PF07855.12 KXH45216.1 - 2.5e-32 112.0 0.0 3e-32 111.7 0.0 1.0 1 0 0 1 1 1 1 Autophagy-related protein 101 Peroxin-3 PF04882.12 KXH45217.1 - 6e-172 572.9 0.3 7e-172 572.6 0.3 1.0 1 0 0 1 1 1 1 Peroxin-3 Sybindin PF04099.12 KXH45218.1 - 5.9e-23 81.4 0.0 7.7e-23 81.0 0.0 1.2 1 0 0 1 1 1 1 Sybindin-like family Pkinase PF00069.25 KXH45219.1 - 1.6e-56 191.6 0.0 3.5e-51 174.1 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXH45219.1 - 1.1e-32 113.4 0.0 2.4e-31 109.0 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KXH45219.1 - 9.3e-05 21.9 0.0 0.00039 19.8 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KXH45219.1 - 0.00039 20.4 0.0 0.00077 19.5 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXH45219.1 - 0.002 16.9 0.0 0.0039 16.0 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase zf-MYND PF01753.18 KXH45220.1 - 5.5e-11 42.4 14.2 9.1e-11 41.7 14.2 1.3 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KXH45220.1 - 0.08 13.3 9.9 0.16 12.3 9.9 1.5 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding zf-Mss51 PF13824.6 KXH45220.1 - 3 8.0 9.6 2.5 8.3 8.2 1.6 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Rhodanese_C PF12368.8 KXH45220.1 - 7.4 7.0 9.7 13 6.3 9.7 1.3 1 0 0 1 1 1 0 Rhodanase C-terminal F-box PF00646.33 KXH45221.1 - 0.0032 17.3 1.1 0.0077 16.1 1.1 1.6 1 0 0 1 1 1 1 F-box domain Ovate PF04844.13 KXH45222.1 - 0.043 13.8 0.1 0.1 12.6 0.1 1.6 1 0 0 1 1 1 0 Transcriptional repressor, ovate Zn_clus PF00172.18 KXH45223.1 - 2.5e-09 37.1 12.5 2.5e-09 37.1 12.5 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KXH45223.1 - 4.1e-08 32.4 0.1 2.1e-07 30.1 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain F-box PF00646.33 KXH45225.1 - 1.1e-05 25.1 0.3 4.2e-05 23.3 0.3 2.0 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KXH45225.1 - 0.0034 17.2 0.5 0.015 15.2 0.1 2.3 2 0 0 2 2 2 1 F-box-like LRR_2 PF07723.13 KXH45225.1 - 0.0069 17.0 0.1 37 5.2 0.0 5.1 6 0 0 6 6 6 1 Leucine Rich Repeat F-box_4 PF15966.5 KXH45225.1 - 0.015 15.2 0.0 0.036 13.9 0.0 1.6 1 0 0 1 1 1 0 F-box Sec10 PF07393.11 KXH45226.1 - 8.2e-220 731.9 10.4 8.2e-220 731.9 10.4 1.3 2 0 0 2 2 2 1 Exocyst complex component Sec10 Phage_Mu_Gam PF07352.12 KXH45226.1 - 0.49 10.3 2.8 0.58 10.0 0.1 2.6 3 0 0 3 3 3 0 Bacteriophage Mu Gam like protein DUF4407 PF14362.6 KXH45226.1 - 4.2 6.6 8.6 2.3 7.5 3.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) HIP1_clath_bdg PF16515.5 KXH45226.1 - 5.5 7.7 10.3 3.5 8.3 3.9 3.5 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 MFS_1 PF07690.16 KXH45227.1 - 8.8e-28 97.2 43.6 1.5e-21 76.7 26.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.13 KXH45227.1 - 0.00042 19.9 5.5 0.00042 19.9 5.5 2.0 1 1 0 2 2 2 1 Nodulin-like LAM_C PF12544.8 KXH45228.1 - 0.00018 21.7 0.1 0.00043 20.4 0.1 1.6 1 0 0 1 1 1 1 Lysine-2,3-aminomutase GTP_EFTU PF00009.27 KXH45249.1 - 1.2e-46 158.7 0.1 5.7e-46 156.5 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.10 KXH45249.1 - 3.9e-24 84.8 1.0 9.2e-24 83.6 1.0 1.6 1 0 0 1 1 1 1 HBS1 N-terminus MMR_HSR1 PF01926.23 KXH45249.1 - 1.6e-09 37.8 0.0 2e-05 24.7 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase GTP_EFTU_D3 PF03143.17 KXH45249.1 - 8.7e-08 32.5 0.2 3e-07 30.7 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KXH45249.1 - 3.8e-07 30.4 0.2 1.3e-06 28.7 0.2 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Roc PF08477.13 KXH45249.1 - 0.00013 22.2 0.0 0.017 15.3 0.0 2.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Septin PF00735.18 KXH45249.1 - 0.0069 15.7 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 Septin Ras PF00071.22 KXH45249.1 - 0.01 15.4 0.1 0.23 11.0 0.0 2.6 2 0 0 2 2 2 0 Ras family SRPRB PF09439.10 KXH45249.1 - 0.041 13.3 0.0 2.7 7.4 0.0 2.7 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit GTP_EFTU_D4 PF14578.6 KXH45249.1 - 0.13 12.1 0.4 0.32 10.9 0.4 1.7 1 0 0 1 1 1 0 Elongation factor Tu domain 4 FeoB_N PF02421.18 KXH45249.1 - 0.15 11.5 0.1 2.9 7.4 0.0 2.6 2 1 0 2 2 2 0 Ferrous iron transport protein B DUF5094 PF17015.5 KXH45249.1 - 3 7.9 6.3 0.22 11.6 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5094) Cpn60_TCP1 PF00118.24 KXH45250.1 - 1.1e-157 525.7 5.0 1.2e-157 525.5 5.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Enolase_N PF03952.16 KXH45250.1 - 0.013 15.7 3.4 8.4 6.6 0.1 3.3 3 0 0 3 3 3 0 Enolase, N-terminal domain His_Phos_1 PF00300.22 KXH45251.1 - 3.5e-15 56.2 3.4 5.5e-15 55.6 0.3 2.5 1 1 1 2 2 2 1 Histidine phosphatase superfamily (branch 1) HTH_OrfB_IS605 PF12323.8 KXH45251.1 - 1.2 8.7 4.0 0.48 10.0 0.7 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain VHS PF00790.19 KXH45252.1 - 4.3e-40 136.8 2.1 1.3e-39 135.2 0.1 2.2 2 0 0 2 2 2 1 VHS domain FYVE PF01363.21 KXH45252.1 - 8.9e-15 54.6 4.2 1.5e-14 53.9 4.2 1.3 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.20 KXH45252.1 - 2.7e-05 23.8 16.5 0.0024 17.6 1.5 2.9 3 0 0 3 3 3 2 Ubiquitin interaction motif GAT PF03127.14 KXH45252.1 - 7.8e-05 22.9 0.1 0.00026 21.2 0.0 2.0 2 0 0 2 2 2 1 GAT domain FYVE_2 PF02318.16 KXH45252.1 - 0.034 14.4 0.2 0.067 13.4 0.2 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger Fer4_2 PF12797.7 KXH45252.1 - 1.2 9.4 8.0 2.3 8.5 0.2 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain UCH PF00443.29 KXH45253.1 - 3.6e-34 118.4 0.0 4.8e-34 118.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KXH45253.1 - 9.3e-19 68.2 0.0 1.8e-18 67.2 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.20 KXH45253.1 - 1.2e-05 25.7 0.0 2.7e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain DUF3671 PF12420.8 KXH45254.1 - 1.3 9.1 5.8 12 6.0 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function PhoLip_ATPase_C PF16212.5 KXH45254.1 - 3.1 7.5 9.8 31 4.2 9.8 2.0 1 1 0 1 1 1 0 Phospholipid-translocating P-type ATPase C-terminal AMP-binding PF00501.28 KXH45255.1 - 5.4e-85 285.5 0.0 7.4e-85 285.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXH45255.1 - 0.00034 21.5 0.1 0.0012 19.8 0.1 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain KH_1 PF00013.29 KXH45256.1 - 5.2e-91 298.5 29.7 2.7e-14 52.7 0.1 13.4 14 1 0 14 14 14 9 KH domain SLS PF14611.6 KXH45256.1 - 3.2e-12 46.8 3.6 0.2 11.4 0.2 7.3 4 2 4 8 8 8 5 Mitochondrial inner-membrane-bound regulator KH_2 PF07650.17 KXH45256.1 - 8.2e-10 38.4 26.4 0.023 14.5 0.2 7.3 6 1 0 7 7 7 4 KH domain KH_4 PF13083.6 KXH45256.1 - 0.059 13.2 12.1 0.33 10.9 0.2 6.0 7 0 0 7 7 7 0 KH domain DUF4974 PF16344.5 KXH45256.1 - 0.1 12.6 0.0 45 4.1 0.0 3.8 5 0 0 5 5 5 0 Domain of unknown function (DUF4974) CTD PF12815.7 KXH45256.1 - 0.15 12.7 2.4 0.42 11.2 2.4 1.7 1 0 0 1 1 1 0 Spt5 C-terminal nonapeptide repeat binding Spt4 DUF2067 PF09840.9 KXH45256.1 - 0.33 10.5 6.2 17 4.9 0.2 4.7 5 0 0 5 5 5 0 Uncharacterized protein conserved in archaea (DUF2067) YqgF PF14639.6 KXH45256.1 - 3.4 7.4 9.3 8 6.2 0.4 4.2 2 1 2 4 4 4 0 Holliday-junction resolvase-like of SPT6 BON PF04972.17 KXH45256.1 - 3.9 7.9 8.0 17 5.8 0.0 4.3 4 0 0 4 4 4 0 BON domain Pkinase PF00069.25 KXH45257.1 - 3.5e-72 243.0 0.0 4.8e-72 242.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXH45257.1 - 9.1e-46 156.2 0.0 1.4e-45 155.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 KXH45257.1 - 1.1e-17 64.1 0.0 3.5e-17 62.5 0.0 2.0 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.6 KXH45257.1 - 1.4e-07 31.2 0.0 3.3e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KXH45257.1 - 9.5e-07 27.9 0.0 2.1e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 KXH45257.1 - 0.0045 16.0 0.0 0.0099 14.9 0.0 1.5 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KXH45257.1 - 0.027 13.8 0.1 0.2 11.0 0.0 2.1 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXH45257.1 - 0.054 13.4 1.1 0.28 11.1 0.0 2.5 2 1 0 2 2 2 0 Phosphotransferase enzyme family CBFD_NFYB_HMF PF00808.23 KXH45301.1 - 3.7e-07 30.3 0.0 4.8e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KXH45301.1 - 2.9e-05 24.4 0.1 3.7e-05 24.1 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 KXH45301.1 - 0.00023 21.2 0.1 0.00036 20.7 0.1 1.3 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-T_C PF15511.6 KXH45301.1 - 0.00083 19.5 0.1 0.0011 19.0 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold DUF5528 PF17666.1 KXH45301.1 - 0.0027 17.7 0.1 0.0029 17.6 0.1 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5528) CENP-S PF15630.6 KXH45301.1 - 0.0094 16.3 0.1 0.015 15.7 0.1 1.4 1 0 0 1 1 1 1 CENP-S protein bZIP_2 PF07716.15 KXH45303.1 - 0.027 14.6 3.5 0.045 13.8 3.5 1.3 1 0 0 1 1 1 0 Basic region leucine zipper bZIP_1 PF00170.21 KXH45303.1 - 0.14 12.3 6.6 0.27 11.3 6.6 1.4 1 0 0 1 1 1 0 bZIP transcription factor Pkinase PF00069.25 KXH45304.1 - 2.1e-39 135.5 0.0 2.5e-39 135.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXH45304.1 - 2.9e-27 95.6 0.0 6e-27 94.6 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXH45304.1 - 0.024 13.4 0.1 0.032 13.0 0.1 1.1 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 KXH45304.1 - 0.032 14.2 0.0 2.8 7.8 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.6 KXH45304.1 - 0.078 12.3 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Acetyltransf_1 PF00583.25 KXH45305.1 - 3.1e-20 72.6 0.0 3.9e-20 72.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXH45305.1 - 1.3e-11 44.5 0.0 2e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXH45305.1 - 1.9e-10 41.0 0.0 2.7e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXH45305.1 - 1.2e-09 38.0 0.0 2.1e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 KXH45305.1 - 8.3e-08 33.0 0.0 9.9e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KXH45305.1 - 6.5e-07 29.5 0.0 1.2e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KXH45305.1 - 1.4e-06 28.0 0.0 1.9e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KXH45305.1 - 0.0011 19.1 0.0 0.002 18.2 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_18 PF18014.1 KXH45305.1 - 0.032 14.1 0.0 0.047 13.5 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 KXH45305.1 - 0.068 12.6 0.0 0.09 12.2 0.0 1.4 1 1 0 1 1 1 0 Putative acetyl-transferase GNAT_acetyltran PF12746.7 KXH45305.1 - 0.085 12.4 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase DUF1917 PF08939.10 KXH45306.1 - 1.1e-70 238.5 1.8 3.4e-68 230.4 1.8 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF1917) Mhr1 PF12829.7 KXH45306.1 - 0.13 12.3 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulation of mitochondrial recombination WD40 PF00400.32 KXH45307.1 - 3.3e-05 24.6 0.2 0.048 14.5 0.0 4.5 5 0 0 5 5 5 1 WD domain, G-beta repeat Xpo1 PF08389.12 KXH45308.1 - 8.4e-09 35.6 0.9 0.00085 19.4 0.0 4.3 3 0 0 3 3 3 2 Exportin 1-like protein IBN_N PF03810.19 KXH45308.1 - 6.1e-05 22.9 0.3 0.00088 19.2 0.1 3.2 2 0 0 2 2 2 1 Importin-beta N-terminal domain Fungal_trans_2 PF11951.8 KXH45309.1 - 2.3e-10 39.9 0.4 4.5e-10 38.9 0.4 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH45309.1 - 1.4e-06 28.3 12.3 2.9e-06 27.3 12.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Herpes_UL25 PF01499.16 KXH45309.1 - 0.057 11.9 0.0 0.093 11.2 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus UL25 family Sec23_trunk PF04811.15 KXH45311.1 - 3.9e-71 239.5 0.0 5.7e-71 238.9 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 KXH45311.1 - 4.8e-26 90.6 0.1 3.3e-25 87.9 0.0 2.4 2 1 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 KXH45311.1 - 8.5e-18 64.9 0.0 2e-17 63.7 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 KXH45311.1 - 9.2e-17 60.8 4.7 1.6e-16 60.1 4.7 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 KXH45311.1 - 1.6e-10 40.7 0.0 4.1e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Gelsolin repeat Vps36-NZF-N PF16988.5 KXH45311.1 - 0.036 13.5 0.1 0.08 12.3 0.1 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Pkinase PF00069.25 KXH45338.1 - 6.2e-69 232.3 0.0 8.6e-69 231.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXH45338.1 - 1.2e-35 123.1 0.0 2.9e-33 115.3 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXH45338.1 - 1.7e-05 24.3 0.7 0.014 14.7 0.0 2.7 2 1 0 2 2 2 2 Kinase-like Haspin_kinase PF12330.8 KXH45338.1 - 0.0012 17.9 0.1 0.0021 17.1 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KXH45338.1 - 0.0021 17.4 0.0 0.0036 16.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXH45338.1 - 0.0049 16.8 0.1 0.0096 15.9 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 KXH45338.1 - 0.012 15.2 0.2 1.8 8.2 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 MHYT PF03707.16 KXH45339.1 - 2.2e-17 63.0 20.3 1.7e-10 40.9 1.1 4.1 4 0 0 4 4 4 3 Bacterial signalling protein N terminal repeat DUF4131 PF13567.6 KXH45339.1 - 2.8 7.6 10.5 1.3 8.7 1.8 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) WD40 PF00400.32 KXH45340.1 - 5.3e-21 74.5 15.8 2.5e-07 31.3 0.1 6.6 7 1 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXH45340.1 - 0.0022 18.2 0.1 10 6.5 0.0 4.2 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WW PF00397.26 KXH45341.1 - 1.1e-09 38.2 0.2 2.4e-09 37.1 0.2 1.6 1 0 0 1 1 1 1 WW domain Pga1 PF10333.9 KXH45342.1 - 2.5e-06 27.5 0.1 1.5e-05 25.0 0.1 2.3 1 1 0 1 1 1 1 GPI-Mannosyltransferase II co-activator Tubulin PF00091.25 KXH45343.1 - 1.4e-66 224.5 0.0 2.1e-66 223.9 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KXH45343.1 - 7.8e-50 168.3 0.1 1.3e-49 167.5 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KXH45343.1 - 0.003 17.2 0.0 0.0074 16.0 0.0 1.7 2 0 0 2 2 2 1 Tubulin domain EF-hand_4 PF12763.7 KXH45344.1 - 1.5e-31 108.4 0.0 5.4e-12 45.6 0.0 3.4 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.6 KXH45344.1 - 3.5e-07 30.6 0.0 0.0017 18.8 0.0 4.1 4 0 0 4 4 4 1 EF-hand domain pair UBA PF00627.31 KXH45344.1 - 9.4e-07 28.6 0.1 2e-06 27.5 0.1 1.5 1 0 0 1 1 1 1 UBA/TS-N domain CENP-F_leu_zip PF10473.9 KXH45344.1 - 0.00018 21.5 31.8 0.0014 18.7 12.9 3.1 1 1 2 3 3 3 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMF_TATA_bd PF12325.8 KXH45344.1 - 0.00038 20.7 26.5 0.027 14.7 4.2 3.3 1 1 2 3 3 3 2 TATA element modulatory factor 1 TATA binding EF-hand_1 PF00036.32 KXH45344.1 - 0.00099 18.5 0.0 36 4.2 0.0 4.7 5 0 0 5 5 5 0 EF hand TolA_bind_tri PF16331.5 KXH45344.1 - 0.001 19.1 34.8 0.52 10.4 2.2 4.6 2 1 2 4 4 4 3 TolA binding protein trimerisation Spc7 PF08317.11 KXH45344.1 - 0.0021 17.0 31.7 0.1 11.4 16.9 2.2 1 1 1 2 2 2 2 Spc7 kinetochore protein GAS PF13851.6 KXH45344.1 - 0.0084 15.5 32.6 0.18 11.1 13.4 2.2 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding EF-hand_6 PF13405.6 KXH45344.1 - 0.01 15.7 0.0 18 5.6 0.0 4.0 5 0 0 5 5 3 0 EF-hand domain DUF3584 PF12128.8 KXH45344.1 - 0.024 12.2 25.4 0.035 11.7 25.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) SOGA PF11365.8 KXH45344.1 - 0.049 14.8 20.1 0.29 12.3 4.8 2.6 2 0 0 2 2 2 0 Protein SOGA TPR_MLP1_2 PF07926.12 KXH45344.1 - 0.055 13.5 36.9 0.26 11.4 20.1 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein YkyA PF10368.9 KXH45344.1 - 0.074 12.7 27.2 0.2 11.3 3.1 3.0 2 1 1 3 3 3 0 Putative cell-wall binding lipoprotein PRKG1_interact PF15898.5 KXH45344.1 - 0.083 13.8 29.9 0.063 14.2 9.5 3.2 1 1 2 3 3 3 0 cGMP-dependent protein kinase interacting domain SYCE1 PF15233.6 KXH45344.1 - 0.12 12.5 25.3 0.13 12.3 17.6 2.2 1 1 1 2 2 2 0 Synaptonemal complex central element protein 1 ADIP PF11559.8 KXH45344.1 - 0.12 12.5 38.3 0.15 12.1 14.8 3.3 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding HAP1_N PF04849.13 KXH45344.1 - 0.32 10.2 28.6 0.47 9.6 16.2 2.1 1 1 1 2 2 2 0 HAP1 N-terminal conserved region LPP PF04728.13 KXH45344.1 - 0.35 11.3 18.4 0.52 10.8 1.0 4.3 3 1 0 4 4 4 0 Lipoprotein leucine-zipper MbeD_MobD PF04899.12 KXH45344.1 - 0.38 10.9 20.9 1.8 8.7 1.6 4.6 2 1 2 4 4 4 0 MbeD/MobD like DUF1664 PF07889.12 KXH45344.1 - 0.42 10.7 17.3 0.72 9.9 3.9 2.4 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) ATG16 PF08614.11 KXH45344.1 - 0.43 10.8 41.6 0.49 10.6 11.4 3.4 2 1 1 3 3 2 0 Autophagy protein 16 (ATG16) DUF2613 PF11021.8 KXH45344.1 - 0.57 10.3 6.6 2.3 8.4 6.6 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) DUF3450 PF11932.8 KXH45344.1 - 0.71 9.1 33.2 2.3 7.5 13.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) kleA_kleC PF17383.2 KXH45344.1 - 1.3 9.4 6.3 19 5.6 1.6 2.9 2 1 1 3 3 3 0 Uncharacterized KorC regulated protein A MscS_porin PF12795.7 KXH45344.1 - 1.5 8.3 41.3 1.5 8.3 24.8 2.1 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain Fez1 PF06818.15 KXH45344.1 - 1.6 9.1 28.9 21 5.5 26.2 2.2 1 1 1 2 2 2 0 Fez1 APG6_N PF17675.1 KXH45344.1 - 1.8 9.1 34.1 1 9.9 20.1 3.2 1 1 2 3 3 3 0 Apg6 coiled-coil region bZIP_2 PF07716.15 KXH45344.1 - 1.9 8.6 10.3 3 8.0 5.0 2.9 2 0 0 2 2 2 0 Basic region leucine zipper AAA_13 PF13166.6 KXH45344.1 - 3.7 6.1 20.8 14 4.2 20.7 1.8 1 1 0 1 1 1 0 AAA domain Filament PF00038.21 KXH45344.1 - 4 6.9 29.9 1.9 8.0 10.8 2.2 1 1 1 2 2 2 0 Intermediate filament protein Golgin_A5 PF09787.9 KXH45344.1 - 4.9 6.5 31.5 1.1 8.6 24.7 1.9 1 1 1 2 2 2 0 Golgin subfamily A member 5 DUF724 PF05266.14 KXH45344.1 - 5.5 6.8 24.8 0.17 11.7 7.2 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF724) DivIC PF04977.15 KXH45344.1 - 5.6 6.8 32.5 0.086 12.6 8.6 4.2 1 1 3 4 4 4 0 Septum formation initiator EzrA PF06160.12 KXH45344.1 - 6.7 4.7 24.6 32 2.5 24.6 1.8 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA Jnk-SapK_ap_N PF09744.9 KXH45344.1 - 8.9 6.5 31.4 7.7 6.7 10.0 2.4 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Sec6 PF06046.13 KXH45345.1 - 8.7e-169 562.6 10.3 1.4e-168 561.9 10.3 1.3 1 0 0 1 1 1 1 Exocyst complex component Sec6 Vps53_N PF04100.12 KXH45345.1 - 0.0053 15.8 1.3 0.0053 15.8 1.3 2.2 2 1 1 3 3 3 1 Vps53-like, N-terminal OmdA PF13376.6 KXH45345.1 - 0.074 13.1 0.8 0.29 11.2 0.0 2.5 3 0 0 3 3 3 0 Bacteriocin-protection, YdeI or OmpD-Associated DUF3829 PF12889.7 KXH45345.1 - 0.15 11.5 2.5 1.9 7.9 0.7 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3829) DUF755 PF05501.11 KXH45345.1 - 0.22 11.8 0.5 0.43 10.9 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Pirin PF02678.16 KXH45346.1 - 5.9e-30 103.4 0.1 1.3e-29 102.4 0.1 1.6 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 KXH45346.1 - 1.1e-26 93.2 0.0 2.4e-25 88.9 0.1 2.2 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.11 KXH45346.1 - 7.2e-07 28.8 3.1 0.00011 21.8 0.7 2.6 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 KXH45346.1 - 0.075 12.7 0.8 0.72 9.6 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF861) Perilipin PF03036.16 KXH45347.1 - 0.00037 19.6 0.0 0.00057 19.0 0.0 1.3 1 0 0 1 1 1 1 Perilipin family SGL PF08450.12 KXH45348.1 - 4.7e-67 226.1 0.0 6.5e-67 225.7 0.0 1.2 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Reg_prop PF07494.11 KXH45348.1 - 0.042 14.1 0.3 1 9.8 0.0 2.8 2 0 0 2 2 2 0 Two component regulator propeller Arylesterase PF01731.20 KXH45348.1 - 0.044 14.0 0.0 0.1 12.8 0.0 1.6 1 0 0 1 1 1 0 Arylesterase PD40 PF07676.12 KXH45348.1 - 0.1 12.6 0.1 0.28 11.2 0.1 1.7 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat Methyltransf_PK PF05891.12 KXH45349.1 - 4.4e-83 278.1 0.0 5e-83 277.9 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_23 PF13489.6 KXH45349.1 - 0.00034 20.5 0.0 0.00073 19.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH45349.1 - 0.0038 17.9 0.0 0.008 16.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH45349.1 - 0.0088 16.7 0.0 0.015 15.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain SR-25 PF10500.9 KXH45350.1 - 0.0028 17.3 11.0 0.0038 16.9 11.0 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein AP3D1 PF06375.11 KXH45350.1 - 0.27 11.4 6.5 0.42 10.8 6.5 1.2 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 GAGA_bind PF06217.12 KXH45350.1 - 0.3 11.4 6.1 0.38 11.0 6.1 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family TAF4 PF05236.14 KXH45350.1 - 2 8.1 14.3 2.6 7.7 14.3 1.1 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family Red1 PF07964.11 KXH45350.1 - 7.8 4.6 7.8 8.9 4.4 7.8 1.0 1 0 0 1 1 1 0 Rec10 / Red1 SIKE PF05769.11 KXH45351.1 - 0.046 13.7 0.4 0.36 10.7 0.0 2.2 2 0 0 2 2 2 0 SIKE family Chitin_bind_1 PF00187.19 KXH45352.1 - 1.4e-25 89.5 199.8 2.3e-07 31.2 25.7 8.7 8 1 1 9 9 9 6 Chitin recognition protein Polysacc_deac_1 PF01522.21 KXH45352.1 - 1.1e-22 80.2 0.1 1.8e-22 79.5 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase SRP-alpha_N PF04086.13 KXH45353.1 - 0.11 12.4 13.7 0.15 12.0 13.7 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Plasmodium_Vir PF05795.11 KXH45353.1 - 0.39 10.1 8.2 0.57 9.6 8.2 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Tim54 PF11711.8 KXH45353.1 - 0.79 8.4 14.1 1.4 7.6 14.1 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DDHD PF02862.17 KXH45353.1 - 0.91 9.6 3.1 1.4 9.0 3.1 1.4 1 0 0 1 1 1 0 DDHD domain CDC45 PF02724.14 KXH45353.1 - 3.3 5.9 12.4 4.2 5.5 12.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 KXH45353.1 - 4.4 6.0 9.8 7 5.3 9.8 1.3 1 0 0 1 1 1 0 Presenilin Connexin PF00029.19 KXH45353.1 - 4.6 6.9 6.3 7.3 6.3 6.3 1.3 1 0 0 1 1 1 0 Connexin NPR3 PF03666.13 KXH45353.1 - 6.8 5.4 9.0 9.4 4.9 9.0 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 TPR_14 PF13428.6 KXH45355.1 - 2.2e-09 37.3 9.8 0.022 15.6 0.1 7.3 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 KXH45355.1 - 2.4e-09 36.6 3.2 0.038 14.1 0.1 6.8 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_1 PF00515.28 KXH45355.1 - 2e-06 27.4 0.1 1.9 8.5 0.0 5.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 KXH45355.1 - 4e-06 26.6 0.4 0.11 12.8 0.0 5.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 KXH45355.1 - 5.2e-06 26.9 4.6 0.0057 17.1 0.1 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 KXH45355.1 - 7.3e-05 23.3 13.5 1.3 9.7 0.0 6.8 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_17 PF13431.6 KXH45355.1 - 0.00012 22.2 4.1 0.034 14.5 0.1 4.6 4 1 1 5 5 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KXH45355.1 - 0.011 15.9 2.5 11 6.3 0.0 4.6 5 0 0 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 KXH45355.1 - 0.069 13.2 3.5 5.3 7.3 0.0 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_9 PF13371.6 KXH45355.1 - 0.12 12.6 2.3 56 4.0 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 KXH45355.1 - 0.15 12.7 2.6 8.6 7.2 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat RIX1 PF08167.12 KXH45356.1 - 1.7e-62 210.5 0.0 5.3e-62 208.9 0.0 1.8 2 0 0 2 2 2 1 rRNA processing/ribosome biogenesis SNAPc19 PF15497.6 KXH45356.1 - 0.2 12.1 7.0 21 5.7 0.0 2.8 2 0 0 2 2 2 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 WW PF00397.26 KXH45357.1 - 3e-08 33.6 2.8 7.3e-08 32.4 2.8 1.7 1 0 0 1 1 1 1 WW domain WRW PF10206.9 KXH45357.1 - 0.015 15.7 0.3 0.03 14.7 0.3 1.4 1 0 0 1 1 1 0 Mitochondrial F1F0-ATP synthase, subunit f Zn_clus PF00172.18 KXH45358.1 - 1.3e-06 28.4 10.7 2.4e-06 27.6 10.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXH45358.1 - 0.0011 18.1 0.0 0.0023 17.0 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain bZIP_2 PF07716.15 KXH45358.1 - 0.1 12.7 1.1 0.27 11.3 1.1 1.8 1 0 0 1 1 1 0 Basic region leucine zipper PAP_central PF04928.17 KXH45358.1 - 0.11 11.4 0.0 0.2 10.6 0.0 1.3 1 0 0 1 1 1 0 Poly(A) polymerase central domain APC_N_CC PF16689.5 KXH45358.1 - 0.69 10.0 2.3 2.3 8.3 0.1 2.5 2 1 0 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain bZIP_1 PF00170.21 KXH45358.1 - 1.9 8.7 4.3 11 6.2 0.1 2.9 2 0 0 2 2 2 0 bZIP transcription factor Glyco_hydro_16 PF00722.21 KXH45359.1 - 7.1e-10 38.6 3.0 1.1e-09 38.0 3.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 PTPLA PF04387.14 KXH45360.1 - 1e-52 178.2 19.1 4.7e-50 169.5 15.3 2.3 2 0 0 2 2 2 2 Protein tyrosine phosphatase-like protein, PTPLA Abhydrolase_6 PF12697.7 KXH45361.1 - 1.8e-05 25.4 2.7 3.5e-05 24.5 2.7 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.14 KXH45361.1 - 0.00014 21.5 0.0 0.00022 20.8 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 KXH45361.1 - 0.0018 18.0 0.0 0.0038 17.0 0.0 1.6 1 0 0 1 1 1 1 PGAP1-like protein Hydrolase_4 PF12146.8 KXH45361.1 - 0.0072 15.6 0.0 0.054 12.8 0.0 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 KXH45361.1 - 0.084 12.7 0.7 0.23 11.3 0.0 2.1 2 0 0 2 2 2 0 alpha/beta hydrolase fold HET PF06985.11 KXH45362.1 - 1.8e-18 67.3 0.8 3.3e-18 66.4 0.8 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF1491 PF07372.12 KXH45362.1 - 0.11 12.9 0.0 0.24 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1491) DIOX_N PF14226.6 KXH45363.1 - 3.4e-24 85.8 0.0 6.6e-24 84.9 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KXH45363.1 - 3.9e-20 72.2 0.0 6.5e-20 71.5 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Amidohydro_2 PF04909.14 KXH45364.1 - 6e-31 108.3 0.0 8.4e-31 107.8 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase TatD_DNase PF01026.21 KXH45364.1 - 0.17 11.2 0.0 0.33 10.3 0.0 1.4 1 0 0 1 1 1 0 TatD related DNase TruD PF01142.18 KXH45365.1 - 2.2e-59 201.3 0.0 3.8e-58 197.3 0.0 2.2 2 0 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) Pkinase PF00069.25 KXH45366.1 - 8.7e-63 212.1 0.0 1e-62 211.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXH45366.1 - 1.1e-34 119.9 0.0 1.5e-34 119.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXH45366.1 - 2.1e-05 24.0 0.0 3.2e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 KXH45366.1 - 0.00051 19.7 0.0 0.82 9.2 0.0 2.2 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 KXH45366.1 - 0.001 18.0 0.0 0.0014 17.5 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase DEAD PF00270.29 KXH45367.1 - 1.6e-40 138.7 0.0 3.8e-40 137.5 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXH45367.1 - 9.8e-30 103.2 0.0 3.9e-29 101.2 0.0 2.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXH45367.1 - 4.1e-06 26.9 0.0 1.4e-05 25.1 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 KXH45367.1 - 0.0033 16.2 0.0 0.0046 15.7 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain PBP1_TM PF14812.6 KXH45367.1 - 0.0045 17.3 2.5 0.012 16.0 2.5 1.6 1 0 0 1 1 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal MCPVI PF02993.14 KXH45367.1 - 0.13 12.1 0.5 0.27 11.0 0.5 1.5 1 0 0 1 1 1 0 Minor capsid protein VI Tnp_DNA_bind PF14706.6 KXH45403.1 - 0.0014 18.4 0.0 1.7 8.6 0.1 3.3 3 0 0 3 3 3 2 Transposase DNA-binding Mid2 PF04478.12 KXH45403.1 - 0.13 12.1 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Fungal_trans_2 PF11951.8 KXH45404.1 - 6.8e-83 278.6 0.0 8.9e-83 278.2 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH45404.1 - 2.1e-08 34.1 5.9 4.2e-08 33.2 5.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FerI PF08151.12 KXH45404.1 - 0.032 14.3 0.0 0.082 13.0 0.0 1.6 1 0 0 1 1 1 0 FerI (NUC094) domain Acetyltransf_13 PF13880.6 KXH45405.1 - 0.06 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase PH PF00169.29 KXH45406.1 - 0.00013 22.4 0.0 0.00049 20.6 0.0 2.0 1 1 0 1 1 1 1 PH domain SAM_2 PF07647.17 KXH45406.1 - 0.0061 16.6 0.0 0.012 15.7 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Sod_Fe_C PF02777.18 KXH45407.1 - 2e-14 53.6 0.0 2e-06 27.9 0.0 2.5 2 0 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain DUF3245 PF11595.8 KXH45408.1 - 0.38 11.2 3.4 22 5.5 1.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) Mito_carr PF00153.27 KXH45409.1 - 7.3e-67 221.4 1.1 1.4e-21 76.2 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KXH45409.1 - 0.63 9.1 6.1 0.92 8.6 0.2 3.2 4 0 0 4 4 4 0 Gammaproteobacterial serine protease Shadoo PF14999.6 KXH45409.1 - 2.6 8.2 5.9 16 5.6 0.7 2.9 3 0 0 3 3 3 0 Shadow of prion protein, neuroprotective IU_nuc_hydro PF01156.19 KXH45410.1 - 6e-85 285.5 0.1 7.1e-85 285.2 0.1 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase RED_N PF07808.13 KXH45411.1 - 4.6e-09 36.2 13.2 4.6e-09 36.2 13.2 2.6 2 1 0 2 2 2 1 RED-like protein N-terminal region IMS PF00817.20 KXH45412.1 - 8.5e-41 139.4 0.0 1.8e-40 138.3 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family REV1_C PF16727.5 KXH45412.1 - 3.5e-28 97.8 1.9 8.7e-28 96.6 1.9 1.7 1 0 0 1 1 1 1 DNA repair protein REV1 C-terminal domain IMS_C PF11799.8 KXH45412.1 - 7.1e-13 49.3 0.0 1.6e-12 48.2 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain UBM PF14377.6 KXH45412.1 - 2.2e-12 46.0 11.2 2.9e-05 23.3 0.0 3.9 4 0 0 4 4 4 3 Ubiquitin binding region BRCT_2 PF16589.5 KXH45412.1 - 1.1e-05 25.8 0.0 2.7e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 KXH45412.1 - 0.0082 16.4 0.0 0.021 15.1 0.0 1.7 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain mCpol PF18182.1 KXH45412.1 - 0.0093 16.3 0.0 0.027 14.8 0.0 1.7 1 0 0 1 1 1 1 minimal CRISPR polymerase domain DUF1805 PF08827.11 KXH45412.1 - 0.013 15.8 0.0 0.12 12.7 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1805) MgtE_N PF03448.17 KXH45412.1 - 0.033 14.8 0.7 13 6.5 0.2 3.4 3 0 0 3 3 3 0 MgtE intracellular N domain IMS_HHH PF11798.8 KXH45412.1 - 0.17 12.2 0.2 1.3 9.5 0.0 2.6 2 0 0 2 2 2 0 IMS family HHH motif WSC PF01822.19 KXH45413.1 - 1.7e-17 63.4 7.8 2.2e-17 63.0 7.8 1.1 1 0 0 1 1 1 1 WSC domain F-box-like PF12937.7 KXH45415.1 - 3.3e-06 26.9 0.2 7.5e-06 25.8 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXH45415.1 - 0.0029 17.4 0.0 0.0083 16.0 0.0 1.8 1 0 0 1 1 1 1 F-box domain COesterase PF00135.28 KXH45416.1 - 1.3e-88 298.1 0.0 1.6e-88 297.8 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXH45416.1 - 0.0069 16.3 0.2 0.021 14.7 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Methyltransf_23 PF13489.6 KXH45417.1 - 2.5e-12 46.9 0.2 1.6e-11 44.3 0.2 2.0 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXH45417.1 - 0.11 12.0 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_31 PF13847.6 KXH45417.1 - 0.12 12.2 0.0 0.5 10.1 0.0 1.8 1 1 1 2 2 2 0 Methyltransferase domain adh_short PF00106.25 KXH45418.1 - 2.1e-38 131.8 0.8 3e-38 131.3 0.8 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXH45418.1 - 2.2e-29 102.7 0.3 3.1e-29 102.2 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH45418.1 - 1.7e-10 41.1 5.3 2.2e-09 37.5 5.3 2.1 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KXH45418.1 - 1.9e-06 27.6 0.9 4.1e-06 26.4 0.9 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXH45418.1 - 0.00013 21.5 0.3 0.00037 20.0 0.1 1.8 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KXH45418.1 - 0.0015 17.6 0.1 0.0021 17.1 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KXH45418.1 - 0.0019 18.1 0.1 0.0029 17.5 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 KXH45418.1 - 0.013 14.6 0.1 0.021 14.0 0.1 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain TrkA_N PF02254.18 KXH45418.1 - 0.036 14.3 0.1 0.071 13.4 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.18 KXH45418.1 - 0.039 13.8 0.1 0.074 12.9 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Gp_dh_N PF00044.24 KXH45418.1 - 0.062 13.6 0.1 0.11 12.8 0.1 1.5 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain ApbA PF02558.16 KXH45418.1 - 0.078 12.6 0.7 0.34 10.6 0.5 2.0 1 1 1 2 2 2 0 Ketopantoate reductase PanE/ApbA NmrA PF05368.13 KXH45418.1 - 0.088 12.3 0.3 0.17 11.4 0.3 1.4 1 0 0 1 1 1 0 NmrA-like family BOP1NT PF08145.12 KXH45420.1 - 9.9e-106 353.4 7.8 1.5e-105 352.8 7.8 1.3 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.32 KXH45420.1 - 2.1e-22 79.0 5.3 2.2e-10 40.9 0.4 6.0 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXH45420.1 - 2.1e-06 28.0 0.1 0.0029 17.9 0.0 4.5 3 2 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Zn_clus PF00172.18 KXH45421.1 - 4.4e-07 29.9 10.1 8.8e-07 28.9 10.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Utp21 PF04192.12 KXH45421.1 - 0.017 14.6 0.0 0.067 12.7 0.0 1.8 2 0 0 2 2 2 0 Utp21 specific WD40 associated putative domain zf-CSL PF05207.13 KXH45421.1 - 0.043 13.5 0.1 0.12 12.1 0.1 1.7 1 0 0 1 1 1 0 CSL zinc finger STIMATE PF12400.8 KXH45422.1 - 7.9e-41 139.5 5.2 1e-40 139.1 4.3 1.6 2 0 0 2 2 2 1 STIMATE family Inhibitor_I53 PF11714.8 KXH45422.1 - 0.2 11.9 2.2 0.61 10.3 2.2 1.8 1 0 0 1 1 1 0 Thrombin inhibitor Madanin Virul_fac_BrkB PF03631.15 KXH45422.1 - 8.5 5.9 12.9 1.9 8.0 0.8 2.4 2 1 0 2 2 2 0 Virulence factor BrkB Methyltransf_23 PF13489.6 KXH45423.1 - 2e-41 141.6 0.0 1.6e-21 76.9 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 KXH45423.1 - 4e-19 69.1 0.1 5.6e-09 36.6 0.0 3.5 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 KXH45423.1 - 4.3e-16 59.5 0.1 1e-05 26.2 0.0 3.7 2 2 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 KXH45423.1 - 5.3e-15 55.5 0.6 1.8e-05 24.6 0.0 3.9 3 1 0 3 3 3 3 Methyltransferase domain Methyltransf_11 PF08241.12 KXH45423.1 - 5.1e-13 49.5 0.0 4.4e-05 24.1 0.0 3.2 2 1 0 2 2 2 2 Methyltransferase domain MTS PF05175.14 KXH45423.1 - 7e-07 29.0 0.1 0.056 13.0 0.0 3.0 3 0 0 3 3 3 2 Methyltransferase small domain Methyltransf_4 PF02390.17 KXH45423.1 - 1.3e-05 24.7 0.0 0.083 12.4 0.0 2.7 3 0 0 3 3 3 2 Putative methyltransferase Methyltransf_16 PF10294.9 KXH45423.1 - 7.4e-05 22.5 0.0 0.21 11.3 0.0 2.3 2 0 0 2 2 2 2 Lysine methyltransferase FtsJ PF01728.19 KXH45423.1 - 0.00022 21.4 0.0 0.74 9.9 0.0 2.3 2 0 0 2 2 2 2 FtsJ-like methyltransferase PrmA PF06325.13 KXH45423.1 - 0.00029 20.3 0.1 0.26 10.7 0.0 2.2 2 0 0 2 2 2 2 Ribosomal protein L11 methyltransferase (PrmA) Sterol_MT_C PF08498.10 KXH45423.1 - 0.0081 16.4 0.0 0.33 11.3 0.0 3.1 3 0 0 3 3 3 1 Sterol methyltransferase C-terminal CMAS PF02353.20 KXH45423.1 - 0.015 14.6 0.0 0.76 9.0 0.0 2.6 2 1 0 2 2 2 0 Mycolic acid cyclopropane synthetase Methyltransf_2 PF00891.18 KXH45423.1 - 0.017 14.5 0.7 5.8 6.1 0.0 2.7 3 0 0 3 3 3 0 O-methyltransferase domain zf-RING_10 PF16685.5 KXH45423.1 - 0.033 14.3 0.0 3.4 7.9 0.0 2.4 2 0 0 2 2 2 0 zinc RING finger of MSL2 PCMT PF01135.19 KXH45423.1 - 0.085 12.6 0.1 3.9 7.2 0.0 2.3 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 KXH45424.1 - 4.1e-16 59.2 0.0 6.1e-16 58.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH45424.1 - 1.2e-08 35.6 0.0 2.5e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH45424.1 - 1.2e-06 28.5 0.0 8.9e-06 25.6 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH45424.1 - 8.4e-06 26.5 0.0 2.6e-05 24.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH45424.1 - 0.00012 22.7 0.0 0.00025 21.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXH45424.1 - 0.017 14.7 0.0 0.11 12.1 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase small domain PrmA PF06325.13 KXH45424.1 - 0.026 13.9 0.0 0.098 12.0 0.0 1.9 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.17 KXH45424.1 - 0.071 12.6 2.9 0.19 11.2 0.0 2.4 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_23 PF13489.6 KXH45425.1 - 1.8e-15 57.1 0.0 3e-15 56.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH45425.1 - 8.5e-06 26.4 0.0 0.00012 22.7 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH45425.1 - 2.5e-05 24.1 0.1 0.0021 17.9 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH45425.1 - 0.00027 21.6 0.0 0.00097 19.8 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH45425.1 - 0.0024 18.5 0.0 0.0084 16.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXH45425.1 - 0.095 12.2 0.0 1.6 8.3 0.0 2.5 3 0 0 3 3 3 0 Methyltransferase small domain Sterol_MT_C PF08498.10 KXH45425.1 - 0.15 12.4 0.0 14 6.1 0.1 3.1 2 1 0 2 2 2 0 Sterol methyltransferase C-terminal Methyltransf_23 PF13489.6 KXH45426.1 - 3.7e-18 65.9 0.0 2.2e-17 63.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH45426.1 - 7.6e-08 33.0 0.0 1.6e-07 31.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH45426.1 - 1e-07 31.8 0.0 1.4e-06 28.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH45426.1 - 0.00036 21.1 0.0 0.00093 19.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH45426.1 - 0.0011 19.7 0.0 0.006 17.3 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KXH45426.1 - 0.0039 16.7 0.0 0.0071 15.8 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.13 KXH45426.1 - 0.0079 15.6 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.19 KXH45426.1 - 0.0081 15.9 0.0 0.017 14.9 0.0 1.5 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 KXH45426.1 - 0.012 15.2 0.0 0.026 14.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Met_10 PF02475.16 KXH45426.1 - 0.21 11.3 0.0 0.42 10.3 0.0 1.4 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_23 PF13489.6 KXH45427.1 - 1.2e-13 51.2 0.0 2.3e-13 50.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH45427.1 - 0.00089 19.9 0.0 0.8 10.4 0.0 2.4 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 KXH45427.1 - 0.13 12.0 0.0 5.4 6.8 0.0 2.1 1 1 1 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.6 KXH45428.1 - 6e-22 78.2 0.0 1.1e-21 77.4 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH45428.1 - 2.2e-10 41.1 0.0 4.9e-10 40.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH45428.1 - 3.3e-08 34.1 0.0 6e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH45428.1 - 7.8e-07 29.8 0.0 3e-06 27.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH45428.1 - 8.3e-07 28.9 0.0 6.4e-06 26.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXH45428.1 - 0.0005 19.5 0.0 0.089 12.1 0.0 2.9 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 KXH45428.1 - 0.0083 15.4 0.0 1.8 7.8 0.0 2.9 3 0 0 3 3 3 1 O-methyltransferase domain Methyltransf_4 PF02390.17 KXH45428.1 - 0.014 14.8 0.1 0.043 13.3 0.0 1.8 2 0 0 2 2 2 0 Putative methyltransferase MTS PF05175.14 KXH45428.1 - 0.14 11.7 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_23 PF13489.6 KXH45429.1 - 2.1e-17 63.4 0.0 3.1e-17 62.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH45429.1 - 1.1e-08 35.7 0.0 2.3e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH45429.1 - 1.2e-06 28.3 0.0 1.2e-05 25.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH45429.1 - 1.4e-06 29.0 0.0 6.7e-06 26.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH45429.1 - 2.1e-06 28.3 0.0 4.6e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KXH45429.1 - 0.0018 17.8 0.0 0.004 16.6 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Ubie_methyltran PF01209.18 KXH45429.1 - 0.052 12.9 0.0 1.4 8.2 0.0 2.1 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 KXH45429.1 - 0.21 10.9 0.0 0.64 9.3 0.0 1.7 2 0 0 2 2 2 0 O-methyltransferase domain Methyltransf_23 PF13489.6 KXH45430.1 - 2.1e-12 47.2 0.0 3.2e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH45430.1 - 0.00079 20.1 0.2 0.42 11.4 0.2 2.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH45430.1 - 0.0083 15.9 0.2 0.6 9.9 0.2 2.2 1 1 0 1 1 1 1 Methyltransferase domain Corona_S2 PF01601.16 KXH45431.1 - 0.61 8.5 16.3 0.82 8.1 16.3 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein RCR PF12273.8 KXH45432.1 - 1.4e-21 77.3 21.4 3.1e-21 76.2 21.4 1.6 1 1 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red Adeno_E3_CR2 PF02439.15 KXH45432.1 - 0.1 12.4 0.5 0.18 11.6 0.5 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 SKG6 PF08693.10 KXH45432.1 - 0.13 11.7 2.4 0.22 11.0 2.4 1.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF4381 PF14316.6 KXH45432.1 - 0.17 12.1 1.3 0.29 11.4 1.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) EphA2_TM PF14575.6 KXH45432.1 - 0.22 12.4 0.1 0.44 11.5 0.1 1.5 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain FAA_hydrolase PF01557.18 KXH45434.1 - 4.1e-51 173.7 0.0 4.8e-51 173.5 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family 3-HAO PF06052.12 KXH45435.1 - 7.5e-66 220.4 0.0 8.7e-66 220.2 0.0 1.1 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.11 KXH45435.1 - 5e-06 26.1 0.0 7.5e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 KXH45435.1 - 0.00017 21.2 0.1 0.00025 20.7 0.1 1.2 1 0 0 1 1 1 1 Cupin DZR PF12773.7 KXH45435.1 - 0.0031 17.5 1.3 0.0093 16.0 1.3 1.8 1 1 0 1 1 1 1 Double zinc ribbon AraC_binding PF02311.19 KXH45435.1 - 0.0053 16.7 0.0 0.0087 16.0 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain TF_Zn_Ribbon PF08271.12 KXH45435.1 - 0.073 12.6 0.2 0.97 9.0 0.0 2.5 2 0 0 2 2 2 0 TFIIB zinc-binding Bowman-Birk_leg PF00228.20 KXH45435.1 - 3.9 8.0 7.0 18 5.9 0.7 3.0 2 1 0 2 2 2 0 Bowman-Birk serine protease inhibitor family Ctr PF04145.15 KXH45436.1 - 6.5e-16 59.3 1.8 3.7e-14 53.6 1.8 2.0 1 1 0 1 1 1 1 Ctr copper transporter family Sperm_Ag_HE2 PF05324.13 KXH45436.1 - 0.071 13.6 0.1 0.13 12.7 0.1 1.3 1 0 0 1 1 1 0 Sperm antigen HE2 Plasmid_stab_B PF10784.9 KXH45436.1 - 0.1 12.5 0.2 0.15 11.9 0.2 1.3 1 0 0 1 1 1 0 Plasmid stability protein NUDIX PF00293.28 KXH45437.1 - 4.3e-09 36.5 0.0 2e-08 34.4 0.0 2.2 2 0 0 2 2 2 1 NUDIX domain FDC-SP PF15215.6 KXH45437.1 - 0.043 14.4 0.1 0.095 13.3 0.1 1.6 1 0 0 1 1 1 0 Follicular dendritic cell secreted peptide Dicty_REP PF05086.12 KXH45437.1 - 1.3 6.9 10.5 1.8 6.4 10.5 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein BAF1_ABF1 PF04684.13 KXH45437.1 - 2.6 7.0 9.6 4.1 6.3 9.6 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Glyco_transf_15 PF01793.16 KXH45439.1 - 5.2e-73 246.1 4.3 1.2e-72 245.0 4.3 1.5 1 1 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase EXS PF03124.14 KXH45440.1 - 1.2e-113 379.8 10.4 1.3e-113 379.7 10.4 1.0 1 0 0 1 1 1 1 EXS family Rad21_Rec8_N PF04825.13 KXH45441.1 - 3.9e-37 126.8 0.0 7.2e-37 125.9 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 KXH45441.1 - 6.1e-09 35.0 0.0 1.1e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein E1-E2_ATPase PF00122.20 KXH45442.1 - 2.6e-44 150.9 0.1 2.6e-44 150.9 0.1 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KXH45442.1 - 1.9e-42 145.0 1.3 3.8e-42 144.1 1.3 1.5 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KXH45442.1 - 1.6e-20 74.3 0.1 1.2e-19 71.4 0.1 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KXH45442.1 - 9e-20 70.1 0.0 1.8e-19 69.2 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 KXH45442.1 - 6e-12 45.5 0.0 1.7e-11 44.0 0.0 1.8 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KXH45442.1 - 0.00056 19.7 0.3 0.00099 18.9 0.3 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KXH45442.1 - 0.012 16.0 0.0 0.03 14.7 0.0 1.8 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase COG4 PF08318.12 KXH45443.1 - 7.8e-124 413.1 0.0 1.1e-123 412.6 0.0 1.2 1 0 0 1 1 1 1 COG4 transport protein TetR_C_12 PF16914.5 KXH45443.1 - 0.005 16.9 0.7 0.054 13.6 0.2 2.8 2 1 0 2 2 2 1 Bacterial transcriptional repressor C-terminal HSCB_C PF07743.13 KXH45443.1 - 0.014 15.9 4.8 0.12 12.9 0.2 3.6 3 0 0 3 3 3 0 HSCB C-terminal oligomerisation domain Autophagy_C PF10381.9 KXH45443.1 - 3.7 7.2 6.5 16 5.1 1.5 2.4 2 0 0 2 2 2 0 Autophagocytosis associated protein C-terminal Leucyl-specific PF14795.6 KXH45444.1 - 0.0046 17.0 0.0 0.0084 16.1 0.0 1.4 1 0 0 1 1 1 1 Leucine-tRNA synthetase-specific domain WD40 PF00400.32 KXH45447.1 - 7.7e-05 23.4 0.1 18 6.4 0.0 4.9 5 1 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXH45447.1 - 0.00015 22.0 0.0 0.32 11.3 0.0 4.6 3 2 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KXH45447.1 - 0.058 13.4 0.5 0.91 9.5 0.0 2.6 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Indigoidine_A PF04227.12 KXH45449.1 - 5e-106 354.3 1.7 7.6e-106 353.7 1.7 1.3 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.24 KXH45449.1 - 3.9e-23 82.2 0.0 5.8e-13 48.8 0.0 2.7 2 1 0 2 2 2 2 pfkB family carbohydrate kinase TspO_MBR PF03073.15 KXH45451.1 - 5.3e-44 149.6 7.6 6.3e-44 149.3 7.6 1.1 1 0 0 1 1 1 1 TspO/MBR family Mito_carr PF00153.27 KXH45452.1 - 5.4e-59 196.1 0.1 1e-19 70.2 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Antimicrobial_6 PF08036.11 KXH45452.1 - 0.45 10.6 2.2 28 4.9 0.4 2.5 2 0 0 2 2 2 0 Diapausin family of antimicrobial peptide DEAD PF00270.29 KXH45453.1 - 7.4e-47 159.4 0.0 4.7e-46 156.8 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXH45453.1 - 1.2e-29 102.9 0.0 4e-28 98.0 0.1 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXH45453.1 - 0.00078 19.5 0.0 0.0028 17.7 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit PRAI PF00697.22 KXH45453.1 - 0.02 14.7 0.1 0.042 13.6 0.1 1.5 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase CMS1 PF14617.6 KXH45453.1 - 4.4 6.6 10.1 0.88 8.9 0.0 2.7 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit Mitoc_mL59 PF18126.1 KXH45454.1 - 1.6e-41 141.6 3.2 1.9e-41 141.4 3.2 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein mL59 zf-CSL PF05207.13 KXH45455.1 - 3.7e-18 65.0 0.7 5.7e-18 64.4 0.7 1.3 1 0 0 1 1 1 1 CSL zinc finger DnaJ PF00226.31 KXH45455.1 - 2.8e-13 49.8 0.7 2.4e-12 46.8 0.7 2.1 1 1 0 1 1 1 1 DnaJ domain 14-3-3 PF00244.20 KXH45456.1 - 1.4e-106 354.9 2.8 1.7e-106 354.7 2.8 1.0 1 0 0 1 1 1 1 14-3-3 protein IATP PF04568.12 KXH45457.1 - 6.8e-30 103.4 2.0 7.6e-30 103.2 2.0 1.0 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP DUF489 PF04356.12 KXH45457.1 - 0.035 14.1 0.5 0.041 13.9 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF489) DUF2205 PF10224.9 KXH45457.1 - 0.091 12.8 3.4 0.13 12.3 3.4 1.2 1 0 0 1 1 1 0 Short coiled-coil protein NPV_P10 PF05531.12 KXH45457.1 - 0.13 12.8 1.0 0.18 12.3 1.0 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein XhlA PF10779.9 KXH45457.1 - 0.27 11.5 2.3 0.41 10.9 2.3 1.3 1 0 0 1 1 1 0 Haemolysin XhlA DUF1003 PF06210.11 KXH45457.1 - 0.47 10.6 1.6 0.68 10.1 1.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1003) Nsp1_C PF05064.13 KXH45458.1 - 8.2e-39 132.0 1.4 8.2e-39 132.0 1.4 1.6 2 0 0 2 2 2 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.6 KXH45458.1 - 7e-20 71.7 199.2 2.1e-07 31.7 33.6 8.5 2 1 4 6 6 6 3 Nucleoporin FG repeat region Myosin_tail_1 PF01576.19 KXH45458.1 - 0.036 11.9 4.5 0.049 11.4 4.5 1.1 1 0 0 1 1 1 0 Myosin tail Nup88 PF10168.9 KXH45458.1 - 0.053 11.3 1.6 0.066 11.0 1.6 1.1 1 0 0 1 1 1 0 Nuclear pore component DUF4200 PF13863.6 KXH45458.1 - 0.085 13.3 2.3 3.3 8.1 0.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) NPV_P10 PF05531.12 KXH45458.1 - 0.48 10.9 1.3 3.6 8.1 0.1 2.6 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein PI_PP_I PF18363.1 KXH45458.1 - 0.49 10.6 3.2 0.3 11.3 0.7 1.8 2 1 0 2 2 2 0 Phosphoinositide phosphatase insertion domain Laminin_II PF06009.12 KXH45458.1 - 1 9.3 3.3 22 5.1 0.2 2.6 1 1 2 3 3 3 0 Laminin Domain II APG6_N PF17675.1 KXH45458.1 - 1.7 9.2 6.7 2.2 8.8 6.2 1.4 1 1 0 1 1 1 0 Apg6 coiled-coil region OmpH PF03938.14 KXH45458.1 - 3.4 8.0 9.6 1.6 9.1 6.6 1.9 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF5102 PF17104.5 KXH45459.1 - 1.2e-115 386.5 1.9 1.2e-115 386.5 1.9 1.8 1 1 1 2 2 2 1 Domain of unknown function (DUF5102) eIF2_C PF09173.11 KXH45460.1 - 2.7e-34 117.3 0.5 6.2e-34 116.1 0.5 1.7 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 KXH45460.1 - 1.2e-22 80.4 1.1 8.5e-22 77.6 1.1 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 KXH45460.1 - 7.8e-11 42.2 0.1 1.7e-10 41.2 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KXH45460.1 - 0.003 17.6 0.0 0.007 16.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 KXH45460.1 - 0.005 16.8 0.8 0.018 15.0 0.1 2.1 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain RsgA_GTPase PF03193.16 KXH45460.1 - 0.022 14.6 0.3 0.23 11.4 0.1 2.2 2 0 0 2 2 2 0 RsgA GTPase Dynamin_N PF00350.23 KXH45460.1 - 0.11 12.6 0.0 0.49 10.4 0.0 2.2 3 0 0 3 3 3 0 Dynamin family Fungal_trans_2 PF11951.8 KXH45462.1 - 5.7e-38 130.7 0.1 9.1e-38 130.1 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pro_isomerase PF00160.21 KXH45463.1 - 1.3e-51 175.0 0.2 4.6e-51 173.2 0.1 1.9 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 KXH45463.1 - 1.9e-12 47.5 0.0 3.4e-05 24.5 0.0 4.9 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXH45463.1 - 0.0001 22.5 0.0 0.064 13.6 0.0 3.5 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KXH45463.1 - 0.012 14.6 0.3 0.16 10.9 0.1 2.2 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Far-17a_AIG1 PF04750.14 KXH45464.1 - 8.2e-48 162.4 10.5 9.4e-48 162.2 10.5 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein DUF3185 PF11381.8 KXH45464.1 - 0.031 14.3 1.9 0.031 14.3 1.9 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) DAHP_synth_1 PF00793.20 KXH45465.1 - 5.5e-100 333.8 0.0 7.1e-100 333.4 0.0 1.1 1 0 0 1 1 1 1 DAHP synthetase I family Cytochrom_C1 PF02167.15 KXH45466.1 - 7.6e-92 307.0 0.0 9.4e-92 306.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 KXH45466.1 - 0.0078 16.5 0.0 0.017 15.4 0.0 1.7 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 KXH45466.1 - 0.18 13.0 0.3 0.68 11.1 0.1 2.1 2 1 0 2 2 2 0 Cytochrome c AAA PF00004.29 KXH45468.1 - 1.2e-40 138.9 0.0 2.2e-40 138.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KXH45468.1 - 2.1e-07 30.6 0.0 5.3e-07 29.3 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 KXH45468.1 - 6.3e-05 23.0 0.1 0.00043 20.3 0.0 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KXH45468.1 - 0.00011 22.4 0.0 0.0069 16.7 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.14 KXH45468.1 - 0.0003 20.9 0.0 0.00083 19.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KXH45468.1 - 0.00051 20.5 0.1 0.01 16.2 0.0 2.3 1 1 0 2 2 2 1 AAA ATPase domain DUF815 PF05673.13 KXH45468.1 - 0.0018 17.5 0.0 0.0033 16.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 KXH45468.1 - 0.008 15.9 0.0 0.016 15.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 KXH45468.1 - 0.025 14.8 0.1 0.063 13.5 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KXH45468.1 - 0.031 13.8 0.0 0.097 12.2 0.0 1.8 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 KXH45468.1 - 0.051 13.7 0.0 0.094 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KXH45468.1 - 0.056 13.8 0.0 0.16 12.4 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_30 PF13604.6 KXH45468.1 - 0.069 12.9 0.1 0.59 9.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.11 KXH45468.1 - 0.08 12.8 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KXH45468.1 - 0.093 12.4 0.1 0.28 10.9 0.0 1.9 2 1 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 KXH45468.1 - 0.1 12.5 0.6 11 5.9 0.0 2.9 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea Mg_chelatase PF01078.21 KXH45468.1 - 0.16 11.3 0.0 0.36 10.2 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Cpn60_TCP1 PF00118.24 KXH45469.1 - 8e-147 489.8 16.1 9e-147 489.6 16.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Phage_tail_X PF05489.12 KXH45469.1 - 0.12 12.1 0.0 0.27 10.9 0.0 1.6 1 0 0 1 1 1 0 Phage Tail Protein X HECT PF00632.25 KXH45469.1 - 0.18 11.2 0.0 0.28 10.6 0.0 1.2 1 0 0 1 1 1 0 HECT-domain (ubiquitin-transferase) AMP-binding PF00501.28 KXH45471.1 - 2.6e-73 247.0 0.0 4.5e-73 246.3 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.26 KXH45471.1 - 1.1e-72 244.7 0.0 2.3e-72 243.6 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KXH45471.1 - 1.4e-52 178.2 2.5 6.5e-52 176.1 2.3 2.3 2 0 0 2 2 2 1 KR domain Condensation PF00668.20 KXH45471.1 - 4.8e-52 177.2 0.0 7.5e-52 176.5 0.0 1.2 1 0 0 1 1 1 1 Condensation domain PS-DH PF14765.6 KXH45471.1 - 6.5e-45 153.6 1.1 1.8e-44 152.2 1.1 1.8 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 KXH45471.1 - 4.9e-44 151.1 0.5 1.1e-43 149.9 0.5 1.6 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KXH45471.1 - 3.5e-27 94.8 0.0 1e-26 93.2 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 KXH45471.1 - 6.9e-21 74.9 0.1 1.6e-19 70.4 0.0 3.3 4 0 0 4 4 3 1 Methyltransferase domain PP-binding PF00550.25 KXH45471.1 - 4.4e-17 62.2 0.0 1.1e-09 38.6 0.0 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site NAD_binding_4 PF07993.12 KXH45471.1 - 9e-14 51.3 0.0 2.4e-13 49.8 0.0 1.7 1 0 0 1 1 1 1 Male sterility protein adh_short PF00106.25 KXH45471.1 - 1.8e-12 47.2 2.7 1.6e-11 44.0 1.4 2.9 3 0 0 3 3 3 1 short chain dehydrogenase Methyltransf_25 PF13649.6 KXH45471.1 - 4.4e-12 46.6 0.1 8.1e-11 42.5 0.0 3.1 3 0 0 3 3 2 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 KXH45471.1 - 8e-12 45.6 0.0 2.2e-11 44.2 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_11 PF08241.12 KXH45471.1 - 4.2e-10 40.1 0.1 2.1e-09 37.9 0.0 2.4 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXH45471.1 - 1.4e-09 38.0 0.0 7.2e-09 35.7 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH45471.1 - 2.5e-07 30.6 0.0 1.1e-06 28.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain adh_short_C2 PF13561.6 KXH45471.1 - 2.4e-06 27.3 1.2 8.5e-06 25.5 1.2 1.9 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Thiolase_N PF00108.23 KXH45471.1 - 3.4e-06 26.6 0.7 1.1e-05 25.0 0.1 2.0 2 0 0 2 2 2 1 Thiolase, N-terminal domain Epimerase PF01370.21 KXH45471.1 - 7.9e-06 25.5 0.0 0.037 13.5 0.0 2.6 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXH45471.1 - 0.0012 17.9 0.0 0.13 11.2 0.0 2.6 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_16 PF10294.9 KXH45471.1 - 0.0034 17.1 0.0 0.0077 16.0 0.0 1.5 1 0 0 1 1 1 1 Lysine methyltransferase Semialdhyde_dh PF01118.24 KXH45471.1 - 0.042 14.3 0.0 0.58 10.6 0.0 2.7 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 KXH45471.1 - 0.069 12.3 0.1 0.54 9.3 0.1 2.1 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein F420_oxidored PF03807.17 KXH45471.1 - 0.073 13.7 0.1 2.3 8.8 0.0 3.1 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Ubie_methyltran PF01209.18 KXH45471.1 - 0.13 11.6 0.0 0.33 10.3 0.0 1.6 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family AMP-binding_C PF13193.6 KXH45471.1 - 0.57 11.2 2.1 19 6.4 0.0 3.9 4 0 0 4 4 3 0 AMP-binding enzyme C-terminal domain p450 PF00067.22 KXH45472.1 - 1.3e-60 205.5 0.0 1.7e-60 205.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ADH_zinc_N PF00107.26 KXH45473.1 - 1.7e-08 34.5 0.0 3.1e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXH45473.1 - 5.8e-06 26.2 0.1 0.00028 20.7 0.0 2.6 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Methyltransf_24 PF13578.6 KXH45474.1 - 5.8e-05 24.1 0.0 0.00011 23.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CmcI PF04989.12 KXH45474.1 - 0.00044 20.0 0.0 0.00069 19.4 0.0 1.2 1 0 0 1 1 1 1 Cephalosporin hydroxylase Adeno_knob PF00541.17 KXH45474.1 - 0.022 14.5 0.0 0.033 13.9 0.0 1.3 1 0 0 1 1 1 0 Adenoviral fibre protein (knob domain) p450 PF00067.22 KXH45475.1 - 5.4e-36 124.3 0.0 1.2e-35 123.2 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 YARHG PF13308.6 KXH45476.1 - 0.069 13.0 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 YARHG domain NOA36 PF06524.12 KXH45476.1 - 0.085 12.2 26.3 0.073 12.4 16.5 2.1 2 0 0 2 2 2 0 NOA36 protein DUF3116 PF11313.8 KXH45476.1 - 0.13 12.1 0.1 0.25 11.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3116) BUD22 PF09073.10 KXH45476.1 - 0.22 10.8 15.9 0.28 10.5 15.9 1.1 1 0 0 1 1 1 0 BUD22 Sigma70_ner PF04546.13 KXH45476.1 - 8 6.3 16.6 6.8 6.5 9.5 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region Pil1 PF13805.6 KXH45477.1 - 7.5e-112 373.1 7.9 9.4e-112 372.8 7.9 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 SpoVT_C PF15714.5 KXH45477.1 - 0.92 9.6 5.7 1.6 8.8 0.1 2.9 3 0 0 3 3 3 0 Stage V sporulation protein T C-terminal, transcription factor Ribophorin_I PF04597.14 KXH45478.1 - 5.9e-153 510.2 3.8 6.9e-153 510.0 3.8 1.0 1 0 0 1 1 1 1 Ribophorin I Hexokinase_2 PF03727.16 KXH45479.1 - 2.3e-83 279.3 0.0 4.1e-83 278.5 0.0 1.4 2 0 0 2 2 2 1 Hexokinase Hexokinase_1 PF00349.21 KXH45479.1 - 1.8e-73 246.7 0.0 6e-73 245.0 0.0 1.7 2 0 0 2 2 2 1 Hexokinase TPP_enzyme_N PF02776.18 KXH45479.1 - 0.094 12.3 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain FGGY_N PF00370.21 KXH45479.1 - 0.11 12.0 0.0 0.29 10.7 0.0 1.7 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, N-terminal domain Ank_2 PF12796.7 KXH45480.1 - 0.0061 17.1 0.0 0.22 12.2 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) VTC PF09359.10 KXH45481.1 - 2.6e-98 328.8 0.0 3.9e-98 328.2 0.0 1.3 1 0 0 1 1 1 1 VTC domain SPX PF03105.19 KXH45481.1 - 4.1e-14 53.3 6.6 3.7e-06 27.1 0.1 4.1 3 1 1 4 4 4 3 SPX domain DUF202 PF02656.15 KXH45481.1 - 1.1e-13 51.4 0.6 2.1e-13 50.5 0.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF202) EBV-NA3 PF05009.12 KXH45481.1 - 0.12 11.9 3.8 0.067 12.7 1.6 1.6 2 0 0 2 2 2 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) HSP20 PF00011.21 KXH45482.1 - 4.3e-10 39.7 0.0 1.1e-08 35.1 0.0 2.1 1 1 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KXH45482.1 - 0.00015 21.3 0.3 0.03 13.9 0.3 3.1 1 1 0 1 1 1 1 HSP20-like domain found in ArsA HasA PF06438.12 KXH45482.1 - 0.12 12.0 0.3 0.18 11.4 0.3 1.3 1 0 0 1 1 1 0 Heme-binding protein A (HasA) Ribosomal_L34 PF00468.17 KXH45483.1 - 1.1e-13 50.9 10.6 1.1e-12 47.7 11.1 2.1 2 0 0 2 2 2 1 Ribosomal protein L34 Peptidase_M48_N PF16491.5 KXH45484.1 - 5.9e-67 225.1 9.0 5.9e-67 225.1 9.0 1.7 2 0 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 KXH45484.1 - 6.7e-45 153.3 0.1 1.3e-44 152.3 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.11 KXH45484.1 - 0.031 13.5 0.1 0.063 12.5 0.1 1.6 1 0 0 1 1 1 0 BlaR1 peptidase M56 Ish1 PF10281.9 KXH45485.1 - 3.3e-05 24.1 0.0 4.4e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Putative stress-responsive nuclear envelope protein Mac PF12464.8 KXH45485.1 - 0.069 13.4 0.7 0.11 12.7 0.7 1.3 1 0 0 1 1 1 0 Maltose acetyltransferase DNA_meth_N PF18284.1 KXH45485.1 - 0.5 10.3 3.2 0.86 9.6 2.1 1.9 1 1 1 2 2 2 0 DNA methylase N-terminal domain Ribosomal_L38e PF01781.18 KXH45486.1 - 3.8e-33 113.4 3.5 4.3e-33 113.2 3.5 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family LAGLIDADG_WhiA PF14527.6 KXH45486.1 - 0.036 14.1 0.1 0.042 13.9 0.1 1.1 1 0 0 1 1 1 0 WhiA LAGLIDADG-like domain ABM PF03992.16 KXH45487.1 - 4.4e-08 33.1 4.7 0.0018 18.3 0.0 3.0 2 1 0 2 2 2 2 Antibiotic biosynthesis monooxygenase DUF4679 PF15728.5 KXH45487.1 - 0.019 14.0 0.0 0.023 13.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4679) GHMP_kinases_N PF00288.26 KXH45488.1 - 3.2e-17 62.5 0.0 7.6e-17 61.3 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KXH45488.1 - 8.6e-09 35.6 0.0 2.2e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.9 KXH45488.1 - 0.0029 17.1 0.0 0.0076 15.8 0.0 1.7 1 0 0 1 1 1 1 Galactokinase galactose-binding signature PPTA PF01239.22 KXH45489.1 - 3.2e-33 112.5 27.4 1.4e-07 31.0 0.2 5.7 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat TPR_14 PF13428.6 KXH45489.1 - 0.17 12.8 1.4 2 9.5 0.6 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat NTF2 PF02136.20 KXH45490.1 - 0.0013 19.3 0.0 0.0042 17.6 0.0 1.8 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain tRNA-synt_1g PF09334.11 KXH45491.1 - 9.1e-98 327.6 0.7 6.6e-97 324.7 0.7 1.9 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 KXH45491.1 - 2.1e-22 79.2 6.6 3.4e-10 38.8 0.2 3.9 1 1 2 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 KXH45491.1 - 3.4e-10 39.8 0.1 4.4e-05 23.0 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain ESCRT-II PF05871.12 KXH45491.1 - 0.046 14.0 0.1 0.12 12.6 0.1 1.7 1 0 0 1 1 1 0 ESCRT-II complex subunit Acetyltransf_3 PF13302.7 KXH45492.1 - 2.8e-16 60.4 0.0 3.8e-16 60.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXH45492.1 - 8.7e-07 29.2 0.0 0.00023 21.4 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family FR47 PF08445.10 KXH45492.1 - 1.3e-05 25.0 0.1 0.11 12.5 0.0 2.4 2 0 0 2 2 2 2 FR47-like protein Acetyltransf_7 PF13508.7 KXH45492.1 - 0.0014 19.0 0.9 0.0031 17.9 0.9 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KXH45492.1 - 0.0042 16.8 0.1 0.72 9.5 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KXH45492.1 - 0.013 15.4 0.1 4.2 7.3 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain PALP PF00291.25 KXH45493.1 - 8.8e-66 222.3 4.5 9.9e-66 222.1 4.5 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ThiC_Rad_SAM PF01964.18 KXH45493.1 - 0.033 13.0 0.1 0.043 12.6 0.1 1.1 1 0 0 1 1 1 0 Radical SAM ThiC family Aminotran_1_2 PF00155.21 KXH45493.1 - 0.055 12.6 0.0 0.22 10.6 0.0 2.0 1 1 0 2 2 2 0 Aminotransferase class I and II DNA_pol_E_B PF04042.16 KXH45495.1 - 3.2e-50 170.4 0.0 4.6e-50 169.9 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 KXH45495.1 - 2e-36 125.0 0.0 3.3e-36 124.3 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain DUF4334 PF14232.6 KXH45495.1 - 0.2 11.6 0.4 0.57 10.2 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4334) ABC_tran PF00005.27 KXH45496.1 - 6.6e-16 59.1 0.1 6.5e-15 55.8 0.1 2.1 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KXH45496.1 - 1.1e-10 41.9 1.2 0.00012 22.0 0.2 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KXH45496.1 - 0.0014 18.3 0.2 0.0037 17.0 0.2 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF3584 PF12128.8 KXH45496.1 - 0.0019 15.9 0.2 0.0024 15.5 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) SMC_N PF02463.19 KXH45496.1 - 0.0019 17.6 0.1 1.8 7.9 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KXH45496.1 - 0.0041 17.6 0.1 0.0058 17.1 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KXH45496.1 - 0.013 15.7 0.2 0.027 14.7 0.2 1.5 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 KXH45496.1 - 0.016 14.9 0.1 0.022 14.5 0.1 1.1 1 0 0 1 1 1 0 AAA ATPase domain AAA_16 PF13191.6 KXH45496.1 - 0.017 15.5 0.9 0.029 14.8 0.9 1.6 1 1 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 KXH45496.1 - 0.019 14.8 0.1 0.029 14.3 0.1 1.2 1 0 0 1 1 1 0 RsgA GTPase AAA_25 PF13481.6 KXH45496.1 - 0.033 13.7 0.2 0.07 12.7 0.2 1.6 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 KXH45496.1 - 0.036 13.8 0.1 0.054 13.2 0.1 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 KXH45496.1 - 0.038 14.3 0.1 0.14 12.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 KXH45496.1 - 0.039 13.6 0.1 0.056 13.1 0.1 1.4 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain Arf PF00025.21 KXH45496.1 - 0.064 12.7 0.2 0.15 11.5 0.2 1.7 1 1 0 1 1 1 0 ADP-ribosylation factor family AAA PF00004.29 KXH45496.1 - 0.11 12.9 0.3 0.38 11.2 0.3 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_13 PF13166.6 KXH45496.1 - 0.14 10.8 0.0 0.19 10.3 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KXH45496.1 - 0.15 12.2 0.1 0.31 11.2 0.1 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KXH45496.1 - 0.18 11.7 0.1 0.29 11.0 0.1 1.3 1 0 0 1 1 1 0 NACHT domain T2SSE PF00437.20 KXH45496.1 - 0.23 10.5 0.1 0.33 10.0 0.1 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein CENP-I PF07778.11 KXH45497.1 - 4.4e-41 141.2 0.0 4.6e-40 137.8 0.0 1.9 1 1 0 1 1 1 1 Mis6 PKHD_C PF18331.1 KXH45497.1 - 0.0029 17.7 0.0 0.044 13.8 0.0 2.5 2 0 0 2 2 2 1 PKHD-type hydroxylase C-terminal domain Acetyltransf_1 PF00583.25 KXH45498.1 - 7.8e-07 29.3 0.0 2.4e-06 27.7 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXH45498.1 - 0.00069 19.6 0.0 0.0044 17.0 0.0 2.2 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXH45498.1 - 0.0033 17.8 0.0 0.0084 16.5 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3384 PF11864.8 KXH45499.1 - 6.4e-132 440.8 1.8 1.3e-131 439.9 0.1 2.2 2 1 0 2 2 2 1 Domain of unknown function (DUF3384) Rap_GAP PF02145.15 KXH45499.1 - 8e-53 178.7 0.0 1.4e-52 177.9 0.0 1.4 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.16 KXH45499.1 - 5.3e-40 137.6 8.6 2.8e-37 128.7 3.5 3.0 3 0 0 3 3 3 2 Tuberin CAS_CSE1 PF03378.15 KXH45500.1 - 6.4e-170 565.4 2.3 8.4e-169 561.7 0.3 2.3 2 0 0 2 2 2 2 CAS/CSE protein, C-terminus Cse1 PF08506.10 KXH45500.1 - 2.8e-157 523.3 3.3 5.1e-157 522.4 3.3 1.5 1 0 0 1 1 1 1 Cse1 IBN_N PF03810.19 KXH45500.1 - 1.4e-15 57.0 0.4 7.4e-15 54.6 0.1 2.5 2 0 0 2 2 2 1 Importin-beta N-terminal domain V-ATPase_H_N PF03224.14 KXH45500.1 - 0.00044 19.6 0.2 0.86 8.8 0.0 4.1 4 2 0 4 4 4 1 V-ATPase subunit H Antiterm PF03589.13 KXH45500.1 - 0.11 12.8 0.0 2.5 8.5 0.0 2.9 2 0 0 2 2 2 0 Antitermination protein Xpo1 PF08389.12 KXH45500.1 - 0.36 10.9 4.6 1.8 8.6 0.6 3.9 3 2 0 3 3 3 0 Exportin 1-like protein SBDS PF01172.18 KXH45537.1 - 6.1e-26 90.3 0.5 7.1e-26 90.1 0.5 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein RhoGEF PF00621.20 KXH45538.1 - 1.8e-24 86.9 0.0 2.9e-24 86.3 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain PX PF00787.24 KXH45538.1 - 0.0085 16.1 0.0 0.024 14.6 0.0 1.7 1 0 0 1 1 1 1 PX domain TF_Otx PF03529.13 KXH45538.1 - 6.6 7.2 10.3 0.19 12.1 0.3 3.0 3 0 0 3 3 3 0 Otx1 transcription factor E1-E2_ATPase PF00122.20 KXH45539.1 - 3.2e-52 176.7 4.8 9.6e-52 175.1 1.6 2.6 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KXH45539.1 - 4.3e-46 156.9 4.4 4.3e-46 156.9 4.4 1.7 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KXH45539.1 - 4.8e-25 89.1 0.8 3.7e-21 76.4 0.1 2.8 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KXH45539.1 - 1.1e-20 73.5 0.0 2.6e-20 72.3 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KXH45539.1 - 1.1e-18 66.7 0.0 2.3e-18 65.6 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KXH45539.1 - 5.2e-08 32.9 1.1 3.2e-06 27.1 0.9 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KXH45539.1 - 3e-06 27.8 0.0 1.2e-05 25.8 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Proteasome PF00227.26 KXH45540.1 - 5.4e-37 127.1 0.0 6.1e-37 127.0 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit TUG-UBL1 PF11470.8 KXH45541.1 - 2.8e-25 88.3 0.1 5.5e-25 87.4 0.1 1.5 1 0 0 1 1 1 1 TUG ubiquitin-like domain UBX PF00789.20 KXH45541.1 - 0.00023 21.3 0.0 0.0011 19.1 0.0 2.1 2 0 0 2 2 2 1 UBX domain DUF4294 PF14127.6 KXH45541.1 - 0.0029 17.5 0.0 0.0062 16.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4294) RBD PF02196.15 KXH45541.1 - 0.0087 16.1 0.1 0.02 15.0 0.1 1.5 1 0 0 1 1 1 1 Raf-like Ras-binding domain Ribosomal_L36e PF01158.18 KXH45542.1 - 3.6e-41 139.3 7.4 4e-41 139.2 7.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e MRP-L28 PF09812.9 KXH45542.1 - 0.046 13.9 1.6 0.054 13.6 1.6 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L28 AltA1 PF16541.5 KXH45543.1 - 0.00069 20.5 0.5 0.0013 19.6 0.3 1.5 1 1 1 2 2 2 1 Alternaria alternata allergen 1 Lipase_3 PF01764.25 KXH45544.1 - 3e-31 108.2 0.0 4.1e-31 107.8 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Thioesterase PF00975.20 KXH45544.1 - 0.00028 21.1 0.0 0.00049 20.3 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.7 KXH45544.1 - 0.00048 20.8 0.0 0.00097 19.8 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXH45544.1 - 0.00063 19.1 0.0 0.001 18.4 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF2974 PF11187.8 KXH45544.1 - 0.01 15.4 0.0 0.11 12.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Abhydrolase_1 PF00561.20 KXH45544.1 - 0.02 14.5 0.0 0.036 13.7 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold PGAP1 PF07819.13 KXH45544.1 - 0.17 11.6 0.0 0.27 10.9 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Peptidase_S8 PF00082.22 KXH45555.1 - 3.1e-36 125.2 2.9 5e-36 124.5 2.9 1.3 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 KXH45555.1 - 7.8e-28 96.3 3.3 8.5e-28 96.2 1.6 2.0 2 0 0 2 2 2 1 Proprotein convertase P-domain S8_pro-domain PF16470.5 KXH45555.1 - 0.096 13.5 0.0 0.25 12.1 0.0 1.7 1 0 0 1 1 1 0 Peptidase S8 pro-domain PX PF00787.24 KXH45556.1 - 2.9e-21 75.6 0.3 8.5e-21 74.1 0.3 1.9 1 0 0 1 1 1 1 PX domain Vps5 PF09325.10 KXH45556.1 - 9.2e-10 38.5 12.6 3.4e-06 26.8 2.3 2.4 2 1 0 2 2 2 2 Vps5 C terminal like FtsH_ext PF06480.15 KXH45556.1 - 0.029 14.7 0.4 0.14 12.6 0.0 2.3 2 0 0 2 2 2 0 FtsH Extracellular Occludin_ELL PF07303.13 KXH45556.1 - 0.046 14.5 5.5 0.1 13.3 0.0 3.5 3 1 0 3 3 3 0 Occludin homology domain DUF1664 PF07889.12 KXH45556.1 - 0.1 12.7 3.1 5.7 7.0 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Sec34 PF04136.15 KXH45556.1 - 0.1 12.5 0.2 0.1 12.5 0.2 2.2 2 1 0 2 2 2 0 Sec34-like family Sigma70_r1_1 PF03979.14 KXH45556.1 - 3.2 7.9 6.9 0.17 11.9 0.4 2.4 2 0 0 2 2 2 0 Sigma-70 factor, region 1.1 LETM1 PF07766.13 KXH45557.1 - 1.4e-105 352.4 0.6 1.4e-105 352.4 0.6 1.5 2 0 0 2 2 2 1 LETM1-like protein SAP PF02037.27 KXH45557.1 - 0.014 15.1 0.1 0.6 9.9 0.0 3.0 3 0 0 3 3 3 0 SAP domain DUF1180 PF06679.12 KXH45557.1 - 5.9 7.3 12.4 0.22 11.9 5.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) ADK PF00406.22 KXH45558.1 - 2.6e-37 128.2 0.0 3.1e-20 72.8 0.0 2.1 2 0 0 2 2 2 2 Adenylate kinase AAA_17 PF13207.6 KXH45558.1 - 3.2e-14 53.5 0.0 4.6e-10 40.1 0.0 2.2 1 1 0 2 2 2 2 AAA domain ADK_lid PF05191.14 KXH45558.1 - 8.9e-14 51.2 0.0 2.1e-13 50.0 0.0 1.7 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.6 KXH45558.1 - 0.00026 21.6 0.0 0.0017 18.9 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KXH45558.1 - 0.0031 17.7 0.0 0.014 15.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KXH45558.1 - 0.074 13.1 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Guanylate_kin PF00625.21 KXH45558.1 - 0.14 11.8 0.1 0.37 10.5 0.0 1.7 2 0 0 2 2 2 0 Guanylate kinase adh_short PF00106.25 KXH45559.1 - 1.4e-23 83.3 0.1 2e-22 79.6 0.1 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXH45559.1 - 3.6e-14 52.9 1.0 5e-13 49.1 1.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH45559.1 - 0.00025 21.0 0.1 0.00051 20.0 0.1 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXH45559.1 - 0.018 14.5 0.1 0.027 14.0 0.1 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXH45559.1 - 0.15 11.4 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase NUDIX PF00293.28 KXH45561.1 - 1.6e-07 31.4 0.7 5.6e-07 29.7 0.7 1.8 1 1 0 1 1 1 1 NUDIX domain LicD PF04991.13 KXH45562.1 - 1.2e-21 77.9 7.8 1.9e-16 60.9 3.1 2.3 1 1 1 2 2 2 2 LicD family zinc_ribbon_2 PF13240.6 KXH45563.1 - 0.033 13.9 0.9 0.076 12.8 0.9 1.6 1 0 0 1 1 1 0 zinc-ribbon domain BTB PF00651.31 KXH45564.1 - 0.0034 17.6 0.1 0.0072 16.5 0.1 1.5 1 0 0 1 1 1 1 BTB/POZ domain AHJR-like PF18743.1 KXH45564.1 - 0.089 12.4 0.1 17 5.0 0.0 2.7 3 0 0 3 3 3 0 REase_AHJR-like zf-C3HC4 PF00097.25 KXH45564.1 - 2 8.3 5.7 4.8 7.1 5.7 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prominin PF05478.11 KXH45565.1 - 0.11 10.4 0.3 0.16 9.9 0.3 1.1 1 0 0 1 1 1 0 Prominin DUF2205 PF10224.9 KXH45565.1 - 0.24 11.4 2.8 1.1 9.4 2.8 2.2 1 0 0 1 1 1 0 Short coiled-coil protein ExbD PF02472.16 KXH45567.1 - 0.054 13.7 2.4 0.11 12.7 0.6 2.1 2 0 0 2 2 2 0 Biopolymer transport protein ExbD/TolR Ndufs5 PF10200.9 KXH45567.1 - 0.18 12.0 2.5 1.1 9.6 1.1 2.6 2 0 0 2 2 2 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa Ribosomal_S17_N PF16205.5 KXH45568.1 - 4.4e-33 113.5 0.6 7.1e-33 112.8 0.6 1.4 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 KXH45568.1 - 1.1e-26 92.8 0.2 2.1e-26 91.8 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein S17 Spc7_N PF15402.6 KXH45569.1 - 3.5e-192 641.1 112.7 2.2e-99 334.0 68.2 4.5 2 1 1 3 3 3 2 N-terminus of kinetochore NMS complex subunit Spc7 Spc7 PF08317.11 KXH45569.1 - 7.7e-121 402.7 10.5 7e-118 393.0 10.5 2.7 1 1 0 1 1 1 1 Spc7 kinetochore protein Spc7_C2 PF15577.6 KXH45569.1 - 1.2e-21 76.5 0.3 2.7e-21 75.4 0.3 1.6 1 0 0 1 1 1 1 Spc7_C2 Cnn_1N PF07989.11 KXH45569.1 - 0.086 13.0 6.4 0.56 10.4 6.4 2.5 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 Meis_PKNOX_N PF16493.5 KXH45569.1 - 0.11 12.8 0.6 0.29 11.5 0.6 1.6 1 0 0 1 1 1 0 N-terminal of Homeobox Meis and PKNOX1 COG2 PF06148.11 KXH45569.1 - 0.42 10.7 4.3 1.2 9.2 4.3 1.7 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 kleA_kleC PF17383.2 KXH45569.1 - 0.42 11.0 4.7 1.9 8.9 4.7 2.2 1 0 0 1 1 1 0 Uncharacterized KorC regulated protein A Laminin_II PF06009.12 KXH45569.1 - 0.58 10.2 7.4 4 7.5 6.4 2.5 1 1 1 2 2 2 0 Laminin Domain II BLOC1_2 PF10046.9 KXH45569.1 - 0.87 9.9 5.3 1.3 9.3 3.2 2.0 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Csm1_N PF18504.1 KXH45569.1 - 3.7 8.0 12.8 0.97 9.8 7.8 2.6 2 0 0 2 2 2 0 Csm1 N-terminal domain Seryl_tRNA_N PF02403.22 KXH45569.1 - 8.5 6.7 11.2 1.2 9.4 5.9 2.5 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Atg14 PF10186.9 KXH45570.1 - 4.3e-76 256.0 0.0 5.5e-76 255.7 0.0 1.0 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 DUF3807 PF12720.7 KXH45572.1 - 6e-37 127.7 2.6 1.2e-36 126.7 2.6 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3807) Pkinase PF00069.25 KXH45573.1 - 3.9e-64 216.6 0.2 4.5e-64 216.3 0.2 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXH45573.1 - 1.4e-18 67.1 0.0 2e-18 66.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXH45573.1 - 9.6e-08 32.2 0.1 1.5e-05 25.0 0.2 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXH45573.1 - 0.0034 16.2 0.0 0.006 15.4 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KXH45573.1 - 0.0099 15.2 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KXH45573.1 - 0.015 14.7 0.0 0.024 14.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KXH45573.1 - 0.023 14.3 0.2 0.023 14.3 0.2 2.0 3 0 0 3 3 3 0 Choline/ethanolamine kinase Aconitase_B_N PF11791.8 KXH45573.1 - 0.13 12.3 0.0 0.38 10.8 0.0 1.7 2 0 0 2 2 2 0 Aconitate B N-terminal domain Scm3 PF10384.9 KXH45574.1 - 2.1e-20 72.2 0.0 1.1e-19 69.8 0.0 2.4 1 0 0 1 1 1 1 Centromere protein Scm3 DUF445 PF04286.12 KXH45574.1 - 0.5 10.1 8.5 0.97 9.2 8.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF445) YpjP PF14005.6 KXH45574.1 - 0.99 9.5 7.4 3 7.9 7.4 1.8 1 0 0 1 1 1 0 YpjP-like protein DUF4371 PF14291.6 KXH45574.1 - 2.2 7.8 6.2 4.2 6.9 6.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4371) APG6 PF04111.12 KXH45575.1 - 6.9e-70 234.6 0.0 1.1e-69 234.0 0.0 1.3 1 0 0 1 1 1 1 Apg6 BARA domain APG6_N PF17675.1 KXH45575.1 - 4.7e-38 130.7 15.1 8.1e-38 130.0 15.1 1.4 1 0 0 1 1 1 1 Apg6 coiled-coil region UPF0242 PF06785.11 KXH45575.1 - 0.67 10.0 11.8 1.2 9.2 11.8 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus AAA PF00004.29 KXH45576.1 - 5.3e-12 46.3 0.0 1.2e-11 45.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KXH45576.1 - 0.00049 20.5 0.1 0.0011 19.4 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KXH45576.1 - 0.078 13.3 0.1 0.25 11.6 0.1 1.7 1 1 1 2 2 2 0 AAA domain AAA_5 PF07728.14 KXH45576.1 - 0.081 12.9 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) CPT PF07931.12 KXH45576.1 - 0.15 11.9 0.0 0.58 10.0 0.0 1.9 1 1 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein LigD_N PF13298.6 KXH45577.1 - 1.5e-34 118.4 0.0 2.4e-34 117.8 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase Ligase (LigD) WD40 PF00400.32 KXH45578.1 - 1.6e-17 63.5 16.1 0.0011 19.7 0.1 7.1 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXH45578.1 - 1.7e-17 63.5 0.0 5.7e-05 23.3 0.0 5.6 4 2 2 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KXH45578.1 - 4.4e-05 23.4 0.2 0.022 14.7 0.0 3.0 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KXH45578.1 - 0.12 11.7 0.0 0.24 10.7 0.0 1.5 1 0 0 1 1 1 0 WD40-like domain Ge1_WD40 PF16529.5 KXH45578.1 - 0.13 11.2 0.1 23 3.8 0.0 3.4 2 1 2 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein HIRA_B PF09453.10 KXH45578.1 - 1.7 8.6 5.7 0.27 11.1 1.1 2.2 2 0 0 2 2 2 0 HIRA B motif Hepatitis_core PF00906.20 KXH45578.1 - 3.8 7.0 8.6 0.3 10.6 1.5 2.3 2 0 0 2 2 2 0 Hepatitis core antigen ABC_tran PF00005.27 KXH45580.1 - 1.4e-49 168.1 0.0 1.8e-30 106.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KXH45580.1 - 7.9e-29 101.2 28.7 6.8e-22 78.4 10.9 3.7 5 0 0 5 5 5 2 ABC transporter transmembrane region SMC_N PF02463.19 KXH45580.1 - 2.2e-09 37.1 2.5 0.00015 21.3 0.3 4.2 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KXH45580.1 - 0.0013 18.7 0.3 1.2 9.0 0.1 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 KXH45580.1 - 0.0015 18.9 0.1 0.43 10.9 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain MMR_HSR1 PF01926.23 KXH45580.1 - 0.0032 17.5 0.0 0.067 13.3 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.6 KXH45580.1 - 0.0034 17.7 0.5 3.6 7.8 0.1 3.2 2 1 0 2 2 2 1 AAA domain T2SSE PF00437.20 KXH45580.1 - 0.0038 16.3 0.1 2.8 6.9 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_29 PF13555.6 KXH45580.1 - 0.0049 16.6 0.9 2.9 7.7 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 KXH45580.1 - 0.009 16.5 2.0 4.6 7.7 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.6 KXH45580.1 - 0.012 15.2 0.1 1.1 8.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 KXH45580.1 - 0.044 13.5 0.7 1.8 8.3 0.0 2.7 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_21 PF13304.6 KXH45580.1 - 0.05 13.4 1.2 16 5.2 0.3 3.6 2 2 2 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 KXH45580.1 - 0.1 12.3 0.0 6.4 6.4 0.1 2.8 3 0 0 3 3 3 0 AAA domain DUF2075 PF09848.9 KXH45580.1 - 0.13 11.5 0.1 2.6 7.2 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_7 PF12775.7 KXH45580.1 - 0.13 11.8 0.3 16 5.0 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_24 PF13479.6 KXH45580.1 - 0.13 11.9 0.0 0.64 9.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 KXH45580.1 - 0.14 11.2 0.1 0.26 10.2 0.1 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB FAM176 PF14851.6 KXH45580.1 - 0.14 11.8 0.2 0.73 9.5 0.1 2.3 2 0 0 2 2 2 0 FAM176 family DUF4834 PF16118.5 KXH45580.1 - 0.17 12.8 0.0 2.5 9.1 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DUF87 PF01935.17 KXH45580.1 - 2.1 8.4 7.2 1.7 8.7 0.2 3.0 3 0 0 3 3 3 0 Helicase HerA, central domain F-box-like PF12937.7 KXH45581.1 - 7.2e-11 41.8 0.0 2.4e-10 40.1 0.0 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXH45581.1 - 5e-09 35.8 0.0 2e-08 33.9 0.0 2.0 2 0 0 2 2 2 1 F-box domain LRR_6 PF13516.6 KXH45581.1 - 2.2e-08 33.5 0.6 0.091 12.9 0.0 5.9 7 0 0 7 7 7 2 Leucine Rich repeat LRR_4 PF12799.7 KXH45581.1 - 7.3e-05 23.1 6.5 0.16 12.4 0.0 4.5 4 2 1 5 5 5 3 Leucine Rich repeats (2 copies) DUF5308 PF17233.2 KXH45581.1 - 0.15 12.3 1.7 0.39 10.9 1.7 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5308) PRANC PF09372.10 KXH45581.1 - 0.17 12.2 0.0 0.52 10.7 0.0 1.8 2 0 0 2 2 2 0 PRANC domain LRR_1 PF00560.33 KXH45581.1 - 0.99 10.2 6.3 85 4.3 0.1 5.5 7 0 0 7 7 7 0 Leucine Rich Repeat Pkinase PF00069.25 KXH45582.1 - 2.9e-51 174.4 0.0 6.5e-51 173.2 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXH45582.1 - 1.1e-17 64.2 0.0 2.4e-17 63.1 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXH45582.1 - 7.2e-06 25.5 0.0 5.5e-05 22.6 0.0 2.2 2 1 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 KXH45582.1 - 8.4e-05 21.7 0.0 0.00014 20.9 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KXH45582.1 - 0.0037 17.2 0.1 0.025 14.5 0.1 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 KXH45582.1 - 0.11 12.1 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Lyase_1 PF00206.20 KXH45585.1 - 1.5e-20 73.8 0.1 2.4e-20 73.2 0.1 1.2 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 KXH45585.1 - 2.2e-17 63.4 0.0 1e-16 61.2 0.0 2.2 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminus DUF4485 PF14846.6 KXH45585.1 - 0.15 12.1 0.0 1.6 8.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4485) Exo_endo_phos_2 PF14529.6 KXH45592.1 - 3.5e-22 78.5 2.1 6.4e-22 77.6 0.3 2.2 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 KXH45592.1 - 9.7e-05 22.0 1.0 0.00017 21.2 0.3 1.7 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family UPF0561 PF10573.9 KXH45593.1 - 0.036 14.2 0.1 0.095 12.8 0.1 1.7 1 0 0 1 1 1 0 Uncharacterised protein family UPF0561 CN_hydrolase PF00795.22 KXH45668.1 - 3.5e-43 147.8 0.0 4e-43 147.6 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Dehydratase_hem PF13816.6 KXH45669.1 - 5.6e-109 364.3 0.0 6.4e-109 364.1 0.0 1.0 1 0 0 1 1 1 1 Haem-containing dehydratase DUF4188 PF13826.6 KXH45669.1 - 4.6e-08 33.4 0.1 0.0017 18.7 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4188) ABM PF03992.16 KXH45669.1 - 0.26 11.5 1.4 4.4 7.5 0.2 2.6 3 0 0 3 3 3 0 Antibiotic biosynthesis monooxygenase Carb_anhydrase PF00194.21 KXH45671.1 - 6.2e-22 78.4 0.0 1.1e-21 77.6 0.0 1.3 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase MGC-24 PF05283.11 KXH45672.1 - 0.00025 21.5 1.7 0.00025 21.5 1.7 2.2 2 0 0 2 2 2 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin TMEM154 PF15102.6 KXH45672.1 - 0.014 15.3 0.0 0.035 14.0 0.0 1.6 1 0 0 1 1 1 0 TMEM154 protein family DUF5518 PF17647.1 KXH45672.1 - 0.12 12.5 6.1 0.31 11.2 6.1 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5518) Amnionless PF14828.6 KXH45672.1 - 0.12 11.2 0.1 0.19 10.5 0.1 1.2 1 0 0 1 1 1 0 Amnionless MtrF PF09472.10 KXH45672.1 - 0.19 11.1 1.1 0.8 9.2 1.1 2.0 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) CHRD PF07452.12 KXH45676.1 - 1.7e-10 41.9 0.1 2.4e-10 41.4 0.1 1.2 1 0 0 1 1 1 1 CHRD domain Peptidase_S9 PF00326.21 KXH45679.1 - 1.5e-41 142.2 0.0 2.3e-41 141.6 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KXH45679.1 - 1.1e-09 37.9 0.7 0.00032 20.1 0.6 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 KXH45679.1 - 6.4e-08 32.5 0.2 0.0076 15.9 0.0 2.3 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.18 KXH45679.1 - 1.4e-05 24.8 0.1 7.4e-05 22.4 0.1 2.0 1 1 0 1 1 1 1 Dienelactone hydrolase family LIP PF03583.14 KXH45679.1 - 0.0016 17.8 0.0 0.0036 16.7 0.0 1.5 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_1 PF00561.20 KXH45679.1 - 0.0053 16.4 0.2 0.033 13.8 0.2 1.9 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 KXH45679.1 - 0.0059 16.5 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold PQQ PF01011.21 KXH45679.1 - 0.0085 16.0 0.1 1.6 8.8 0.1 3.2 3 0 0 3 3 2 1 PQQ enzyme repeat PD40 PF07676.12 KXH45679.1 - 0.056 13.4 0.1 8.8 6.4 0.0 2.9 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Gmad1 PF10647.9 KXH45679.1 - 0.077 12.7 0.2 7.6 6.2 0.0 2.4 2 0 0 2 2 2 0 Lipoprotein LpqB beta-propeller domain PQQ_2 PF13360.6 KXH45679.1 - 0.099 12.2 0.5 5.1 6.6 0.1 2.9 2 2 1 3 3 3 0 PQQ-like domain FSH1 PF03959.13 KXH45679.1 - 0.14 11.8 0.0 0.29 10.8 0.0 1.5 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 KXH45679.1 - 0.23 11.2 0.0 0.42 10.4 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase DUF4926 PF16277.5 KXH45680.1 - 0.042 13.2 0.2 0.13 11.6 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4926) Fungal_trans PF04082.18 KXH45681.1 - 1.8e-56 191.1 0.1 2.7e-56 190.6 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KXH45681.1 - 5.4e-07 29.7 6.4 0.016 15.7 0.2 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXH45681.1 - 0.00021 21.9 5.6 0.29 12.1 0.2 3.2 2 0 0 2 2 2 2 C2H2-type zinc finger FOXP-CC PF16159.5 KXH45681.1 - 0.11 13.2 1.3 4.4 8.0 0.3 2.5 1 1 1 2 2 2 0 FOXP coiled-coil domain Ribosomal_S8 PF00410.19 KXH45682.1 - 2e-09 37.5 0.0 2.5e-09 37.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S8 LAGLIDADG_WhiA PF14527.6 KXH45682.1 - 0.19 11.8 0.0 0.27 11.3 0.0 1.3 1 0 0 1 1 1 0 WhiA LAGLIDADG-like domain Amidohydro_1 PF01979.20 KXH45683.1 - 4.7e-32 111.6 0.1 6.5e-32 111.2 0.1 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KXH45683.1 - 2e-15 57.2 4.2 7e-11 42.2 0.2 2.2 1 1 1 2 2 2 2 Amidohydrolase family Cupin_1 PF00190.22 KXH45685.1 - 1e-18 67.4 0.0 1.5e-18 66.9 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.11 KXH45685.1 - 0.00028 20.6 0.0 0.00093 18.9 0.0 1.8 1 1 0 1 1 1 1 Cupin domain Ank_2 PF12796.7 KXH45686.1 - 7.7e-18 64.9 0.3 1.9e-13 50.8 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXH45686.1 - 5.4e-15 55.6 0.0 1.3e-07 32.0 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXH45686.1 - 1.5e-14 53.9 0.1 4.1e-07 30.1 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXH45686.1 - 1.4e-11 43.6 0.0 0.00012 22.2 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 KXH45686.1 - 1e-10 41.5 0.1 0.00011 22.5 0.1 2.7 3 0 0 3 3 3 2 Ankyrin repeat Phe_tRNA-synt_N PF02912.18 KXH45686.1 - 0.014 15.4 0.0 0.06 13.3 0.0 1.9 2 0 0 2 2 2 0 Aminoacyl tRNA synthetase class II, N-terminal domain TP6A_N PF04406.14 KXH45687.1 - 1.4e-16 60.2 0.1 2.6e-16 59.3 0.1 1.5 1 0 0 1 1 1 1 Type IIB DNA topoisomerase SQHop_cyclase_C PF13243.6 KXH45688.1 - 1.9e-47 161.9 1.2 2.8e-45 154.8 0.7 2.4 2 1 0 2 2 2 2 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 KXH45688.1 - 2.6e-35 121.9 11.2 1.2e-32 113.2 1.4 3.9 3 1 2 5 5 5 3 Squalene-hopene cyclase N-terminal domain Prenyltrans PF00432.21 KXH45688.1 - 6e-27 93.1 4.8 8.5e-10 38.2 0.5 5.1 4 0 0 4 4 4 3 Prenyltransferase and squalene oxidase repeat Pec_lyase PF09492.10 KXH45688.1 - 0.0028 17.0 0.2 3.9 6.7 0.0 3.0 3 0 0 3 3 3 2 Pectic acid lyase Phage_F PF02305.17 KXH45688.1 - 0.032 13.0 0.1 0.047 12.4 0.1 1.1 1 0 0 1 1 1 0 Capsid protein (F protein) SGS PF05002.15 KXH45689.1 - 1.1e-28 99.2 1.6 1.1e-28 99.2 1.6 2.0 2 0 0 2 2 2 1 SGS domain CS PF04969.16 KXH45689.1 - 6.5e-11 43.1 0.1 1.6e-10 41.8 0.0 1.7 2 0 0 2 2 2 1 CS domain TPR_2 PF07719.17 KXH45689.1 - 0.0014 18.6 0.1 8.1 6.8 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 KXH45689.1 - 0.0051 17.4 3.1 4.1 8.1 5.1 3.1 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 KXH45689.1 - 0.095 12.6 0.1 4.9 7.2 0.2 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TauD PF02668.16 KXH45690.1 - 6.4e-43 147.5 0.0 1.2e-42 146.6 0.0 1.4 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 KXH45690.1 - 5.7e-05 23.7 0.0 0.00014 22.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF971) CsiD PF08943.10 KXH45690.1 - 0.00088 18.5 0.0 0.0025 17.0 0.0 1.6 2 0 0 2 2 2 1 CsiD tRNA_int_endo PF01974.17 KXH45691.1 - 8.8e-17 61.0 0.0 1.7e-16 60.1 0.0 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.14 KXH45691.1 - 0.0026 17.4 0.0 1.3 8.7 0.0 2.5 2 0 0 2 2 2 2 tRNA intron endonuclease, N-terminal domain Glyco_transf_21 PF13506.6 KXH45692.1 - 4.2e-12 45.9 0.0 0.00021 20.8 0.0 3.2 3 0 0 3 3 3 3 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 KXH45692.1 - 5.1e-07 29.8 0.0 1.9e-05 24.7 0.0 2.7 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KXH45692.1 - 0.0023 17.8 0.0 0.023 14.5 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 2 Tannase PF07519.11 KXH45693.1 - 2.2e-121 406.0 0.1 2.6e-121 405.8 0.1 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Hydrolase_4 PF12146.8 KXH45693.1 - 0.022 14.0 0.0 0.041 13.1 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KXH45693.1 - 0.074 12.7 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Fungal_trans_2 PF11951.8 KXH45694.1 - 1.4e-15 57.0 0.0 2.1e-15 56.5 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH45694.1 - 0.00031 20.8 6.2 0.00062 19.8 6.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NUDIX PF00293.28 KXH45695.1 - 0.0029 17.6 0.0 0.0065 16.5 0.0 1.6 1 0 0 1 1 1 1 NUDIX domain COesterase PF00135.28 KXH45696.1 - 1.6e-82 278.1 0.0 1.4e-52 179.2 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family FTZ PF03867.14 KXH45696.1 - 0.1 12.1 0.1 0.17 11.4 0.1 1.2 1 0 0 1 1 1 0 Fushi tarazu (FTZ), N-terminal region Acyl-CoA_dh_2 PF08028.11 KXH45699.1 - 2.3e-13 50.6 0.0 3.8e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KXH45699.1 - 2.2e-05 24.6 0.2 7.4e-05 22.9 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KXH45699.1 - 0.0058 17.3 0.0 0.01 16.4 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 KXH45699.1 - 0.013 15.7 0.7 0.048 13.9 0.1 2.0 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain Gpr1_Fun34_YaaH PF01184.19 KXH45700.1 - 1.1e-41 142.7 16.2 1.4e-41 142.4 16.2 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF3784 PF12650.7 KXH45700.1 - 0.026 14.7 3.8 0.026 14.7 3.8 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF3784) Bac_luciferase PF00296.20 KXH45701.1 - 3.3e-63 214.0 0.0 4.2e-63 213.7 0.0 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase p450 PF00067.22 KXH45702.1 - 8.3e-58 196.2 0.0 1.3e-57 195.6 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 Mito_carr PF00153.27 KXH45703.1 - 1.4e-19 69.7 6.3 2.3e-08 33.8 0.2 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein F-box PF00646.33 KXH45704.1 - 0.025 14.5 0.0 0.079 12.9 0.0 1.8 1 0 0 1 1 1 0 F-box domain ACPS PF01648.20 KXH45710.1 - 1.5e-07 31.5 0.0 8.7e-07 29.1 0.0 2.2 2 1 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily Pet191_N PF10203.9 KXH45711.1 - 1.6e-27 95.6 4.9 2e-27 95.2 4.9 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 COBRA PF04833.15 KXH45711.1 - 0.061 13.2 0.3 0.084 12.8 0.3 1.3 1 0 0 1 1 1 0 COBRA-like protein PAN_3 PF08277.12 KXH45711.1 - 0.089 12.6 0.6 0.17 11.7 0.6 1.5 1 0 0 1 1 1 0 PAN-like domain CX9C PF16860.5 KXH45711.1 - 0.18 11.8 8.5 0.44 10.6 1.1 2.7 1 1 2 3 3 3 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Abhydrolase_1 PF00561.20 KXH45712.1 - 2.1e-23 83.3 0.2 1.2e-22 80.8 0.2 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 KXH45712.1 - 3.1e-21 74.7 0.1 6.1e-21 73.8 0.1 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Hydrolase_4 PF12146.8 KXH45712.1 - 0.00015 21.2 0.0 0.016 14.5 0.0 2.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 FSH1 PF03959.13 KXH45712.1 - 0.00034 20.4 0.1 0.33 10.6 0.0 2.3 2 0 0 2 2 2 2 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 KXH45712.1 - 0.16 11.8 0.1 24 4.6 0.0 2.4 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase RTA1 PF04479.13 KXH45713.1 - 6.1e-76 254.6 2.1 6.1e-76 254.6 2.1 2.0 1 1 1 2 2 2 2 RTA1 like protein zf-CCCH PF00642.24 KXH45714.1 - 0.023 14.6 0.0 0.037 14.0 0.0 1.3 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Spc7 PF08317.11 KXH45714.1 - 0.11 11.3 10.3 0.36 9.7 10.3 1.8 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF874 PF05917.11 KXH45714.1 - 0.38 9.8 8.0 0.82 8.6 8.0 1.5 1 0 0 1 1 1 0 Helicobacter pylori protein of unknown function (DUF874) Spc24 PF08286.11 KXH45714.1 - 1.1 9.5 5.6 4.4 7.6 5.6 2.1 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 Myosin_head PF00063.21 KXH45715.1 - 1.2e-268 892.9 0.0 1.2e-268 892.9 0.0 1.8 2 0 0 2 2 2 1 Myosin head (motor domain) Myosin_N PF02736.19 KXH45715.1 - 4.9e-13 48.7 0.5 1.2e-12 47.5 0.5 1.7 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Myosin_tail_1 PF01576.19 KXH45715.1 - 2.5e-10 38.9 51.4 2.5e-10 38.9 51.4 5.1 2 2 2 4 4 4 3 Myosin tail AAA_22 PF13401.6 KXH45715.1 - 0.09 13.1 0.0 0.09 13.1 0.0 4.7 5 0 0 5 5 5 0 AAA domain UDPG_MGDP_dh_N PF03721.14 KXH45715.1 - 0.17 11.5 3.9 0.54 9.8 3.9 1.8 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Spo7 PF03907.13 KXH45715.1 - 0.18 11.3 5.9 0.22 11.0 0.2 3.2 2 0 0 2 2 2 0 Spo7-like protein Annexin PF00191.20 KXH45716.1 - 2.4e-16 59.6 0.2 0.00032 20.7 0.0 4.3 4 0 0 4 4 4 3 Annexin DUF5617 PF18493.1 KXH45716.1 - 0.022 14.9 0.2 0.055 13.6 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5617) Lyase_1 PF00206.20 KXH45717.1 - 3.4e-113 378.1 0.0 4.7e-113 377.7 0.0 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 KXH45717.1 - 1.1e-21 76.9 0.0 3.1e-21 75.5 0.0 1.8 1 0 0 1 1 1 1 Fumarase C C-terminus T7SS_ESX_EspC PF10824.8 KXH45717.1 - 0.11 12.9 0.3 0.43 11.1 0.3 2.0 1 0 0 1 1 1 0 Excreted virulence factor EspC, type VII ESX diderm Ank_2 PF12796.7 KXH45718.1 - 1.2e-19 70.6 0.1 4.4e-09 36.8 0.0 4.0 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXH45718.1 - 6.8e-14 52.0 0.1 1.7e-05 25.3 0.0 4.2 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXH45718.1 - 5.1e-12 44.9 0.1 0.14 12.8 0.0 6.5 6 0 0 6 6 6 3 Ankyrin repeat Ank PF00023.30 KXH45718.1 - 1.7e-11 44.0 3.8 4.7e-05 23.6 0.2 5.2 4 1 1 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 KXH45718.1 - 6.2e-11 42.3 0.9 0.17 12.2 0.0 5.7 3 2 3 6 6 6 5 Ankyrin repeats (many copies) AAA_16 PF13191.6 KXH45718.1 - 4.5e-06 27.2 0.9 6e-05 23.5 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 KXH45718.1 - 5.9e-06 26.3 0.0 2.6e-05 24.2 0.0 2.2 1 1 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 KXH45718.1 - 0.00027 21.2 0.4 0.0012 19.1 0.0 2.3 3 0 0 3 3 3 1 AAA domain KAP_NTPase PF07693.14 KXH45718.1 - 0.0076 15.5 0.6 1.8 7.8 0.2 2.4 1 1 0 2 2 2 2 KAP family P-loop domain AAA_30 PF13604.6 KXH45718.1 - 0.11 12.2 0.0 3.2 7.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain MDMPI_N PF11716.8 KXH45720.1 - 0.0066 17.1 0.0 0.0098 16.6 0.0 1.2 1 0 0 1 1 1 1 Mycothiol maleylpyruvate isomerase N-terminal domain GPI2 PF06432.11 KXH45721.1 - 2.4e-135 450.4 1.5 2.9e-135 450.2 1.5 1.1 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase Mito_fiss_reg PF05308.11 KXH45721.1 - 0.031 14.4 0.1 0.031 14.4 0.1 2.4 2 1 1 3 3 3 0 Mitochondrial fission regulator Hexapep_2 PF14602.6 KXH45721.1 - 1.3 8.9 9.0 2.2 8.1 9.0 1.4 1 0 0 1 1 1 0 Hexapeptide repeat of succinyl-transferase PilJ PF13675.6 KXH45722.1 - 0.014 15.4 0.5 0.028 14.4 0.5 1.5 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF2205 PF10224.9 KXH45722.1 - 0.036 14.1 2.6 0.11 12.5 2.6 1.8 1 1 0 1 1 1 0 Short coiled-coil protein HET PF06985.11 KXH45723.1 - 4.9e-24 85.3 0.3 7.4e-23 81.5 0.3 2.2 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) UQ_con PF00179.26 KXH45724.1 - 6.1e-48 162.0 0.0 6.9e-48 161.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KXH45724.1 - 0.00055 19.7 0.0 0.00074 19.2 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 KXH45724.1 - 0.0042 16.9 0.1 0.0082 16.0 0.1 1.5 1 1 0 1 1 1 1 UEV domain RWD PF05773.22 KXH45724.1 - 0.07 13.4 0.0 0.091 13.1 0.0 1.3 1 0 0 1 1 1 0 RWD domain WD40 PF00400.32 KXH45725.1 - 9.1e-09 35.8 18.2 0.0024 18.7 0.5 5.3 4 0 0 4 4 4 2 WD domain, G-beta repeat Zn_ribbon_17 PF17120.5 KXH45725.1 - 2.7e-06 26.9 9.3 5.9e-06 25.8 9.3 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type RWD PF05773.22 KXH45725.1 - 0.00096 19.4 0.0 0.0021 18.3 0.0 1.5 1 0 0 1 1 1 1 RWD domain SBP_bac_11 PF13531.6 KXH45725.1 - 0.11 12.2 0.7 0.22 11.2 0.1 1.8 2 0 0 2 2 2 0 Bacterial extracellular solute-binding protein zf-RING_9 PF13901.6 KXH45725.1 - 0.44 10.5 5.7 0.97 9.4 5.7 1.5 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon zf-RING_2 PF13639.6 KXH45725.1 - 0.65 10.4 10.9 0.027 14.8 4.6 2.0 2 0 0 2 2 2 0 Ring finger domain zf-RING_UBOX PF13445.6 KXH45725.1 - 0.85 9.7 6.7 1.8 8.6 6.7 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-rbx1 PF12678.7 KXH45725.1 - 4.4 7.7 13.7 0.081 13.2 6.2 2.0 2 0 0 2 2 2 0 RING-H2 zinc finger domain ADH_zinc_N PF00107.26 KXH45727.1 - 1.3e-14 54.2 0.0 2.4e-14 53.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXH45727.1 - 0.015 15.1 0.0 0.037 13.9 0.0 1.7 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain COesterase PF00135.28 KXH45730.1 - 1.7e-88 297.7 0.0 2.1e-88 297.4 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXH45730.1 - 0.0022 17.9 0.4 0.024 14.5 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Aspzincin_M35 PF14521.6 KXH45732.1 - 2.5e-28 99.4 1.6 3.7e-28 98.9 1.6 1.2 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase HRXXH PF13933.6 KXH45732.1 - 0.0023 17.6 0.9 0.76 9.3 0.1 2.3 2 1 0 2 2 2 2 Putative peptidase family Peptidase_C1_2 PF03051.15 KXH45735.1 - 4.8e-151 503.5 0.0 5.5e-151 503.3 0.0 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.23 KXH45735.1 - 2.9e-07 30.8 0.1 0.0011 19.1 0.1 2.6 2 1 0 2 2 2 2 Papain family cysteine protease DUF4644 PF15486.6 KXH45735.1 - 0.054 13.3 0.1 0.12 12.2 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4644) DUF2408 PF10303.9 KXH45736.1 - 0.0043 17.6 0.1 1.4 9.5 0.1 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF2408) Cep57_CLD PF14073.6 KXH45736.1 - 0.019 15.0 0.1 0.023 14.7 0.1 1.2 1 0 0 1 1 1 0 Centrosome localisation domain of Cep57 Herpes_TK_C PF08465.10 KXH45736.1 - 0.076 12.8 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Thymidine kinase from Herpesvirus C-terminal XPB_DRD PF18458.1 KXH45736.1 - 0.11 12.4 0.5 0.6 10.0 0.1 2.4 3 0 0 3 3 3 0 Xeroderma pigmentosum group B helicase damage recognition domain Epimerase PF01370.21 KXH45738.1 - 4e-05 23.2 0.0 4.7e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KXH45738.1 - 0.00032 20.6 0.0 0.00045 20.2 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding 2-Hacid_dh_C PF02826.19 KXH45738.1 - 0.0036 16.7 0.1 0.0043 16.4 0.1 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.17 KXH45738.1 - 0.01 15.0 0.0 0.011 14.8 0.0 1.1 1 0 0 1 1 1 0 RmlD substrate binding domain adh_short PF00106.25 KXH45738.1 - 0.012 15.1 0.4 0.05 13.0 0.3 1.8 1 1 1 2 2 2 0 short chain dehydrogenase KR PF08659.10 KXH45738.1 - 0.024 14.6 0.0 0.027 14.4 0.0 1.2 1 0 0 1 1 1 0 KR domain Semialdhyde_dh PF01118.24 KXH45738.1 - 0.025 15.0 0.0 0.028 14.9 0.0 1.2 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 KXH45738.1 - 0.031 14.4 0.0 0.035 14.2 0.0 1.2 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NmrA PF05368.13 KXH45738.1 - 0.045 13.3 0.0 0.064 12.8 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family eIF-5a PF01287.20 KXH45741.1 - 1.2e-06 28.5 0.0 2.1e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold TGF_beta_GS PF08515.12 KXH45741.1 - 0.0071 15.8 0.9 0.014 14.8 0.9 1.4 1 0 0 1 1 1 1 Transforming growth factor beta type I GS-motif GATA PF00320.27 KXH45758.1 - 1.3e-29 101.5 17.9 1.7e-15 56.3 3.0 2.7 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 KXH45758.1 - 3.2e-06 26.5 4.8 0.0052 16.3 0.4 2.5 2 0 0 2 2 2 2 TFIIB zinc-binding ArfGap PF01412.18 KXH45758.1 - 0.00056 20.0 1.9 0.49 10.5 0.3 2.3 2 0 0 2 2 2 2 Putative GTPase activating protein for Arf Auto_anti-p27 PF06677.12 KXH45758.1 - 0.002 18.3 6.2 0.14 12.3 0.9 2.6 2 0 0 2 2 2 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Zn-ribbon_8 PF09723.10 KXH45758.1 - 0.0052 16.9 9.3 0.086 13.0 0.1 2.8 3 0 0 3 3 2 2 Zinc ribbon domain OrfB_Zn_ribbon PF07282.11 KXH45758.1 - 0.019 14.9 2.1 0.019 14.9 2.1 2.8 3 0 0 3 3 3 0 Putative transposase DNA-binding domain zf-RRN7 PF11781.8 KXH45758.1 - 0.038 13.7 9.4 0.088 12.5 0.5 2.9 2 1 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 eIF-5_eIF-2B PF01873.17 KXH45758.1 - 0.11 12.4 4.8 2.9 7.8 0.3 2.4 2 0 0 2 2 2 0 Domain found in IF2B/IF5 DZR PF12773.7 KXH45758.1 - 0.15 12.1 11.7 0.52 10.4 0.4 3.0 2 1 0 2 2 2 0 Double zinc ribbon NMD3 PF04981.13 KXH45758.1 - 0.35 10.3 1.7 6 6.3 0.1 2.2 2 0 0 2 2 2 0 NMD3 family zf-Sec23_Sec24 PF04810.15 KXH45758.1 - 2.4 8.3 14.3 0.072 13.2 0.8 3.1 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger Rubredoxin_2 PF18073.1 KXH45758.1 - 7.5 6.4 10.1 30 4.4 0.1 4.4 4 0 0 4 4 4 0 Rubredoxin metal binding domain zinc_ribbon_4 PF13717.6 KXH45758.1 - 7.8 6.5 6.4 3.4 7.7 0.1 3.0 3 0 0 3 3 3 0 zinc-ribbon domain COPI_assoc PF08507.10 KXH45759.1 - 4.6e-35 120.5 6.3 5.2e-35 120.3 6.3 1.0 1 0 0 1 1 1 1 COPI associated protein UCR_Fe-S_N PF10399.9 KXH45759.1 - 0.031 13.6 0.1 0.031 13.6 0.1 1.7 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Cg6151-P PF10233.9 KXH45759.1 - 0.32 11.3 9.6 0.58 10.5 9.6 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein CG6151-P DUF2583 PF10762.9 KXH45759.1 - 0.55 10.7 3.4 4 7.9 0.2 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF2583) TMEM72 PF16054.5 KXH45759.1 - 0.57 9.8 5.8 1.2 8.8 1.9 2.0 2 0 0 2 2 2 0 Transmembrane protein family 72 Cytochrom_B558a PF05038.13 KXH45759.1 - 2.8 7.5 5.1 0.7 9.4 1.6 1.7 1 1 1 2 2 2 0 Cytochrome Cytochrome b558 alpha-subunit GTP_EFTU PF00009.27 KXH45760.1 - 2.1e-54 184.0 0.0 6.2e-54 182.5 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 KXH45760.1 - 5.2e-23 80.9 0.0 1.1e-22 79.9 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 KXH45760.1 - 3.8e-11 42.9 0.0 5.2e-05 23.2 0.0 2.7 2 0 0 2 2 2 2 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KXH45760.1 - 9.7e-07 29.1 0.0 2.5e-06 27.8 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_IV PF03764.18 KXH45760.1 - 0.00032 20.5 0.1 0.00071 19.4 0.1 1.7 1 1 0 1 1 1 1 Elongation factor G, domain IV RF3_C PF16658.5 KXH45760.1 - 0.0013 18.5 0.0 0.0093 15.8 0.0 2.2 2 0 0 2 2 2 1 Class II release factor RF3, C-terminal domain RPE65 PF03055.15 KXH45761.1 - 1.3e-98 331.2 0.1 1.5e-98 331.0 0.1 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein MmgE_PrpD PF03972.14 KXH45762.1 - 2.4e-66 224.1 0.6 2.9e-66 223.9 0.6 1.0 1 0 0 1 1 1 1 MmgE/PrpD family NAD_binding_5 PF07994.12 KXH45762.1 - 0.11 11.8 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Myo-inositol-1-phosphate synthase Uteroglobin PF01099.17 KXH45763.1 - 0.064 13.6 1.8 0.36 11.2 0.3 2.7 2 0 0 2 2 2 0 Uteroglobin family DUF987 PF06174.11 KXH45764.1 - 0.15 12.0 1.2 2.3 8.2 0.0 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF987) CBM-like PF14683.6 KXH45764.1 - 0.19 11.6 2.8 3.5 7.5 0.3 2.1 1 1 0 2 2 2 0 Polysaccharide lyase family 4, domain III T7SS_ESX1_EccB PF05108.13 KXH45765.1 - 0.0051 15.5 0.1 0.007 15.1 0.1 1.1 1 0 0 1 1 1 1 Type VII secretion system ESX-1, transport TM domain B HTH_40 PF14493.6 KXH45765.1 - 0.026 15.0 0.2 0.072 13.6 0.2 1.9 1 1 0 1 1 1 0 Helix-turn-helix domain Cupin_1 PF00190.22 KXH45766.1 - 1e-15 57.7 0.1 1.5e-15 57.1 0.1 1.2 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.11 KXH45766.1 - 0.072 12.8 0.0 0.12 12.1 0.0 1.4 1 1 0 1 1 1 0 Cupin domain SUN PF03856.13 KXH45767.1 - 1.2e-73 247.6 13.3 1.7e-73 247.1 13.3 1.2 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) DUF572 PF04502.13 KXH45767.1 - 1.6 8.3 6.1 2.4 7.7 6.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Mito_fiss_reg PF05308.11 KXH45767.1 - 8.6 6.4 11.9 14 5.6 11.9 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator MFS_1 PF07690.16 KXH45769.1 - 1.7e-32 112.7 23.8 9.1e-30 103.8 14.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4381 PF14316.6 KXH45769.1 - 0.03 14.6 0.6 6.1 7.1 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4381) LCM PF04072.14 KXH45771.1 - 1.4e-21 77.3 0.0 4.3e-21 75.7 0.0 1.8 2 1 0 2 2 2 1 Leucine carboxyl methyltransferase Mito_carr PF00153.27 KXH45772.1 - 0.13 12.2 0.1 13 5.8 0.0 2.4 2 0 0 2 2 2 0 Mitochondrial carrier protein Kinesin PF00225.23 KXH45773.1 - 7.6e-113 376.8 0.4 7.6e-113 376.8 0.4 1.8 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KXH45773.1 - 3.2e-27 95.3 0.1 1.5e-26 93.2 0.1 2.2 1 0 0 1 1 1 1 Microtubule binding UQ_con PF00179.26 KXH45774.1 - 5.4e-52 175.2 0.1 6.1e-52 175.0 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KXH45774.1 - 0.00062 19.5 0.0 0.00069 19.3 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KXH45774.1 - 0.038 14.3 0.0 0.048 13.9 0.0 1.4 1 1 0 1 1 1 0 RWD domain Thiolase_N PF00108.23 KXH45775.1 - 2.2e-85 286.2 0.9 3.8e-85 285.4 0.9 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KXH45775.1 - 2.1e-37 127.5 0.9 4.9e-37 126.3 0.9 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KXH45775.1 - 0.00063 19.4 0.4 0.0015 18.2 0.3 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain PCI PF01399.27 KXH45776.1 - 0.00019 21.9 0.0 0.014 15.9 0.0 2.5 2 0 0 2 2 2 2 PCI domain Clat_adaptor_s PF01217.20 KXH45777.1 - 3.8e-56 189.0 1.7 4.1e-56 188.8 1.7 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain zf-CCHC_2 PF13696.6 KXH45778.1 - 1.8e-09 37.3 23.3 4e-08 32.9 5.3 2.4 2 0 0 2 2 2 2 Zinc knuckle Ist1 PF03398.14 KXH45779.1 - 3.4e-62 209.2 2.1 5e-62 208.7 2.1 1.3 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway TFIID-18kDa PF02269.16 KXH45780.1 - 3.4e-27 94.3 2.1 1.4e-26 92.3 0.2 2.6 3 0 0 3 3 3 1 Transcription initiation factor IID, 18kD subunit Myc_N PF01056.18 KXH45780.1 - 0.058 13.3 0.3 0.11 12.3 0.3 1.4 1 0 0 1 1 1 0 Myc amino-terminal region TAFII28 PF04719.14 KXH45780.1 - 0.063 13.4 0.0 0.19 11.8 0.0 1.8 1 1 0 1 1 1 0 hTAFII28-like protein conserved region Med3 PF11593.8 KXH45780.1 - 0.13 11.4 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Fungal_trans_2 PF11951.8 KXH45781.1 - 9.8e-07 27.9 4.7 4.8e-06 25.6 0.5 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain Corona_nucleoca PF00937.18 KXH45781.1 - 0.25 10.3 2.2 0.37 9.8 2.2 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Citrate_synt PF00285.21 KXH45782.1 - 7.3e-97 324.7 0.0 9.6e-97 324.3 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain G-patch_2 PF12656.7 KXH45782.1 - 0.014 15.4 0.0 0.03 14.4 0.0 1.5 1 0 0 1 1 1 0 G-patch domain Ovate PF04844.13 KXH45782.1 - 0.082 12.9 0.1 8.6 6.4 0.1 2.6 2 0 0 2 2 2 0 Transcriptional repressor, ovate HHH_8 PF14716.6 KXH45782.1 - 0.14 12.5 0.0 0.61 10.5 0.0 2.1 2 0 0 2 2 2 0 Helix-hairpin-helix domain DUF3500 PF12006.8 KXH45783.1 - 1.3e-70 238.3 0.0 1.5e-70 238.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3500) p450 PF00067.22 KXH45784.1 - 2.2e-41 142.1 0.0 4.2e-26 91.7 0.0 2.6 2 1 0 2 2 2 2 Cytochrome P450 DAO PF01266.24 KXH45786.1 - 2e-36 126.3 0.1 2.6e-36 126.0 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KXH45786.1 - 0.00027 20.3 0.0 0.011 15.1 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXH45786.1 - 0.0015 18.7 0.1 0.0039 17.4 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KXH45786.1 - 0.017 15.1 0.6 0.13 12.2 0.1 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding K_oxygenase PF13434.6 KXH45786.1 - 0.024 13.8 0.0 0.035 13.2 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 KXH45786.1 - 0.031 13.0 0.1 5.2 5.7 0.2 2.1 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_2 PF00890.24 KXH45786.1 - 0.046 12.8 0.2 7.4 5.5 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.17 KXH45786.1 - 0.15 11.3 0.0 0.26 10.5 0.0 1.3 1 0 0 1 1 1 0 Thi4 family PDZ_1 PF12812.7 KXH45788.1 - 4.3e-53 177.2 0.0 5.1e-35 119.3 0.0 2.6 2 0 0 2 2 2 2 PDZ-like domain Trypsin_2 PF13365.6 KXH45788.1 - 1.4e-23 84.5 2.5 1.8e-20 74.3 0.2 2.6 2 0 0 2 2 2 2 Trypsin-like peptidase domain PDZ_2 PF13180.6 KXH45788.1 - 4.6e-13 49.3 4.2 1e-05 25.8 0.2 4.5 4 0 0 4 4 4 3 PDZ domain PDZ_6 PF17820.1 KXH45788.1 - 7e-12 45.0 0.0 3e-05 23.8 0.4 3.7 3 0 0 3 3 3 3 PDZ domain PDZ PF00595.24 KXH45788.1 - 8.1e-08 32.5 0.0 0.00086 19.6 0.0 3.7 4 0 0 4 4 4 2 PDZ domain Tricorn_PDZ PF14685.6 KXH45788.1 - 0.0017 18.3 0.8 0.027 14.4 0.3 3.1 4 0 0 4 4 4 1 Tricorn protease PDZ domain Trypsin PF00089.26 KXH45788.1 - 0.0034 17.2 0.0 0.015 15.1 0.0 2.1 2 1 0 2 2 2 1 Trypsin 4HPAD_g_N PF18671.1 KXH45788.1 - 0.077 12.7 0.0 0.25 11.1 0.0 1.9 1 0 0 1 1 1 0 4-Hydroxyphenylacetate decarboxylase subunit gamma N-terminal Peptidase_S46 PF10459.9 KXH45788.1 - 0.17 10.5 0.4 0.31 9.6 0.2 1.4 2 0 0 2 2 2 0 Peptidase S46 DnaJ PF00226.31 KXH45790.1 - 2.2e-22 79.0 1.6 4.5e-22 77.9 1.6 1.6 1 0 0 1 1 1 1 DnaJ domain CDC73_C PF05179.14 KXH45791.1 - 2.6e-53 179.9 0.0 4.3e-53 179.2 0.0 1.3 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal Bystin PF05291.11 KXH45793.1 - 1.1e-124 415.5 0.0 1.4e-124 415.1 0.0 1.1 1 0 0 1 1 1 1 Bystin DUF383 PF04063.14 KXH45794.1 - 5.6e-67 225.1 0.8 6.9e-65 218.3 0.2 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF383) DUF384 PF04064.13 KXH45794.1 - 5.3e-21 74.2 0.2 1.5e-20 72.8 0.2 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF384) Adaptin_N PF01602.20 KXH45794.1 - 0.012 14.2 0.3 0.023 13.3 0.3 1.4 1 0 0 1 1 1 0 Adaptin N terminal region NTP_transf_9 PF04248.12 KXH45795.1 - 1.7e-30 104.8 2.5 2.5e-30 104.2 2.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF427) RSN1_7TM PF02714.15 KXH45796.1 - 7.2e-80 268.2 19.3 7.2e-80 268.2 19.3 2.1 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KXH45796.1 - 8.6e-41 139.3 0.2 8.6e-41 139.3 0.2 3.3 3 1 1 4 4 4 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KXH45796.1 - 1.9e-28 99.9 1.2 1e-15 58.4 0.2 2.5 2 0 0 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 KXH45796.1 - 1.8e-15 56.9 0.0 4.9e-15 55.5 0.0 1.8 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter FAD_binding_3 PF01494.19 KXH45797.1 - 4.3e-18 65.7 0.0 3.6e-17 62.6 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KXH45797.1 - 1.6e-07 31.4 0.3 3.9e-07 30.2 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXH45797.1 - 0.00051 19.7 1.3 0.0033 17.1 1.5 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXH45797.1 - 0.0015 17.9 0.5 0.0034 16.6 0.6 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXH45797.1 - 0.0023 17.1 0.8 0.0047 16.1 0.8 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 KXH45797.1 - 0.01 15.1 0.3 0.028 13.7 0.6 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.21 KXH45797.1 - 0.019 14.3 0.1 0.035 13.5 0.1 1.4 1 0 0 1 1 1 0 ThiF family Thi4 PF01946.17 KXH45797.1 - 0.052 12.8 0.1 0.099 11.9 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Skp1_POZ PF03931.15 KXH45797.1 - 0.13 12.5 0.0 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 Skp1 family, tetramerisation domain GIDA PF01134.22 KXH45797.1 - 0.18 10.9 1.1 0.26 10.3 1.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A HI0933_like PF03486.14 KXH45797.1 - 0.24 10.0 0.6 0.42 9.3 0.6 1.3 1 0 0 1 1 1 0 HI0933-like protein HgmA PF04209.13 KXH45800.1 - 8.3e-132 439.9 0.3 1.7e-131 438.8 0.3 1.4 1 1 0 1 1 1 1 homogentisate 1,2-dioxygenase Lon_C PF05362.13 KXH45804.1 - 1.6e-68 230.3 0.7 6.7e-68 228.3 0.4 2.0 2 0 0 2 2 2 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 KXH45804.1 - 1.7e-27 96.7 0.0 3.4e-27 95.7 0.0 1.5 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 KXH45804.1 - 1.3e-22 80.6 0.0 3.4e-22 79.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ChlI PF13541.6 KXH45804.1 - 5.6e-09 35.9 0.1 8.5e-08 32.1 0.0 2.4 2 0 0 2 2 2 1 Subunit ChlI of Mg-chelatase AAA_5 PF07728.14 KXH45804.1 - 2.7e-07 30.7 0.0 8.3e-07 29.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 KXH45804.1 - 2.9e-05 23.9 0.0 7.5e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_16 PF13191.6 KXH45804.1 - 4.2e-05 24.0 1.3 0.00016 22.1 0.1 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_3 PF07726.11 KXH45804.1 - 0.00028 20.7 0.0 0.00064 19.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KXH45804.1 - 0.00037 20.3 0.0 0.0014 18.4 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KXH45804.1 - 0.00049 20.4 0.0 0.025 14.9 0.0 2.8 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.14 KXH45804.1 - 0.00078 19.6 0.0 0.005 17.0 0.0 2.2 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 KXH45804.1 - 0.0011 18.2 0.1 0.0023 17.2 0.1 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_25 PF13481.6 KXH45804.1 - 0.018 14.6 0.0 0.063 12.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KXH45804.1 - 0.022 14.7 0.0 0.066 13.1 0.0 1.8 1 0 0 1 1 1 0 NACHT domain AAA_18 PF13238.6 KXH45804.1 - 0.031 14.8 0.0 0.08 13.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KXH45804.1 - 0.032 14.4 0.0 0.074 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KXH45804.1 - 0.075 12.9 0.0 0.24 11.3 0.0 1.8 1 0 0 1 1 1 0 RsgA GTPase NTPase_1 PF03266.15 KXH45804.1 - 0.1 12.5 0.0 0.32 10.9 0.0 1.9 1 1 0 1 1 1 0 NTPase RNA_helicase PF00910.22 KXH45804.1 - 0.1 13.0 0.0 0.37 11.2 0.0 2.0 2 0 0 2 2 1 0 RNA helicase TsaE PF02367.17 KXH45804.1 - 0.1 12.6 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_23 PF13476.6 KXH45804.1 - 0.2 12.1 0.0 0.2 12.1 0.0 3.5 2 1 1 3 3 1 0 AAA domain AAA_11 PF13086.6 KXH45804.1 - 0.41 10.4 0.0 0.41 10.4 0.0 2.4 1 1 1 2 2 2 0 AAA domain RPA_C PF08784.11 KXH45805.1 - 1.4e-18 67.5 0.8 6.9e-18 65.2 0.1 2.2 2 0 0 2 2 2 1 Replication protein A C terminal tRNA_anti-codon PF01336.25 KXH45805.1 - 1.2e-08 34.8 0.1 3.4e-08 33.4 0.0 1.7 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain Acetyltransf_1 PF00583.25 KXH45806.1 - 5.9e-08 33.0 0.1 1e-07 32.2 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXH45806.1 - 1.9e-07 31.0 0.0 3.4e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXH45806.1 - 3.6e-07 30.5 0.0 6.3e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KXH45806.1 - 5.2e-07 29.8 0.0 9.5e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KXH45806.1 - 0.0015 18.6 0.0 0.0026 17.9 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase GNAT_acetyltran PF12746.7 KXH45806.1 - 0.1 12.2 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase FR47 PF08445.10 KXH45806.1 - 0.16 11.9 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein NUDIX PF00293.28 KXH45807.1 - 1.2e-27 96.5 0.0 1.8e-27 96.0 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain MatE PF01554.18 KXH45808.1 - 2.2e-53 180.2 34.0 3.1e-34 118.0 9.6 2.5 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.6 KXH45808.1 - 0.00068 19.7 9.6 0.00068 19.7 9.6 3.9 3 1 2 5 5 5 1 Polysaccharide biosynthesis C-terminal domain RPN1_RPN2_N PF17781.1 KXH45809.1 - 2.7e-112 375.2 0.9 4.3e-112 374.5 0.9 1.3 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 KXH45809.1 - 4.8e-29 100.2 0.0 8.3e-29 99.4 0.0 1.4 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 KXH45809.1 - 1.3e-19 69.5 11.8 9e-05 22.7 0.2 8.2 7 0 0 7 7 7 3 Proteasome/cyclosome repeat HEAT_2 PF13646.6 KXH45809.1 - 1.2e-07 32.1 1.0 0.0095 16.3 0.0 4.4 5 1 1 6 6 6 3 HEAT repeats DUF848 PF05852.11 KXH45809.1 - 0.063 13.4 2.1 0.15 12.2 2.1 1.6 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) HAND PF09110.11 KXH45809.1 - 0.34 11.7 7.5 0.72 10.6 7.5 1.5 1 0 0 1 1 1 0 HAND Pinin_SDK_memA PF04696.13 KXH45809.1 - 0.44 10.6 4.1 0.83 9.7 4.1 1.3 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region RIO1 PF01163.22 KXH45810.1 - 2.7e-42 144.5 0.1 2e-29 102.5 0.0 2.2 2 0 0 2 2 2 2 RIO1 family Rio2_N PF09202.11 KXH45810.1 - 9.5e-29 99.4 0.1 3.3e-28 97.7 0.1 1.9 2 0 0 2 2 2 1 Rio2, N-terminal APH PF01636.23 KXH45810.1 - 4.2e-08 33.4 0.0 0.00021 21.3 0.0 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 KXH45810.1 - 8.5e-06 25.3 0.0 0.00072 19.0 0.0 2.5 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Raftlin PF15250.6 KXH45810.1 - 0.19 10.4 3.3 0.29 9.8 3.3 1.2 1 0 0 1 1 1 0 Raftlin NOA36 PF06524.12 KXH45810.1 - 6.7 5.9 9.9 10 5.3 9.9 1.2 1 0 0 1 1 1 0 NOA36 protein RRM_1 PF00076.22 KXH45811.1 - 3e-25 87.8 0.0 3.5e-11 42.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Fungal_trans PF04082.18 KXH45850.1 - 2.6e-15 56.2 2.5 4.6e-15 55.4 2.5 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.6 KXH45850.1 - 0.00043 20.6 7.6 0.095 13.2 1.0 3.1 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 KXH45850.1 - 0.0019 18.6 12.1 0.1 13.1 2.9 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_3rep PF18868.1 KXH45850.1 - 0.031 14.9 0.0 6.7 7.4 0.0 2.8 2 0 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_jaz PF12171.8 KXH45850.1 - 0.89 9.9 6.8 0.37 11.1 2.9 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding UDPGT PF00201.18 KXH45864.1 - 2.9e-05 23.1 0.0 4.2e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_transf_28 PF03033.20 KXH45864.1 - 0.0087 16.1 0.0 0.017 15.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain B12-binding PF02310.19 KXH45864.1 - 0.034 14.2 0.0 0.18 11.8 0.0 2.3 2 1 1 3 3 3 0 B12 binding domain Cu-oxidase PF00394.22 KXH45865.1 - 5.9e-32 111.0 0.2 7e-31 107.5 0.1 2.2 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 KXH45865.1 - 3e-28 98.2 0.0 3e-28 98.2 0.0 2.9 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KXH45865.1 - 5.6e-23 81.2 6.6 7.2e-20 71.1 1.7 3.4 2 1 0 2 2 2 2 Multicopper oxidase p450 PF00067.22 KXH45866.1 - 1.3e-71 241.7 0.0 1.7e-71 241.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 KXH45867.1 - 3.9e-32 111.6 27.0 3.9e-32 111.6 27.0 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF4118 PF13493.6 KXH45867.1 - 0.11 12.4 0.1 0.11 12.4 0.1 3.1 4 1 0 4 4 4 0 Domain of unknown function (DUF4118) Arylsulfotran_2 PF14269.6 KXH45868.1 - 1.1e-58 198.9 0.0 1.8e-58 198.3 0.0 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KXH45868.1 - 1.1e-20 73.9 0.0 8.2e-20 71.0 0.0 2.0 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) BLM10_mid PF16507.5 KXH45869.1 - 5.2e-197 655.7 0.0 9.3e-197 654.8 0.0 1.4 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 KXH45869.1 - 2.1e-29 101.3 0.0 1e-28 99.1 0.0 2.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) BLM10_N PF16547.5 KXH45869.1 - 4.2e-22 78.2 0.1 1.3e-21 76.6 0.1 2.0 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, N-terminal Adaptin_N PF01602.20 KXH45869.1 - 0.17 10.4 0.0 21 3.5 0.0 3.1 2 1 0 3 3 3 0 Adaptin N terminal region HEAT PF02985.22 KXH45869.1 - 0.5 10.8 5.9 9.3 6.8 0.1 5.2 5 0 0 5 5 5 0 HEAT repeat SLAC1 PF03595.17 KXH45870.1 - 3.9e-85 286.0 46.9 4.5e-85 285.8 46.9 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Mannosyl_trans2 PF04188.13 KXH45872.1 - 4.1e-56 191.2 7.5 5e-56 190.9 7.5 1.1 1 0 0 1 1 1 1 Mannosyltransferase (PIG-V) PMT PF02366.18 KXH45872.1 - 0.00087 18.9 5.5 0.00087 18.9 5.5 2.1 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Phage_GPD PF05954.11 KXH45872.1 - 0.071 12.4 0.0 0.36 10.1 0.0 2.0 2 0 0 2 2 2 0 Phage late control gene D protein (GPD) Glyco_hydro_16 PF00722.21 KXH45874.1 - 6.2e-11 42.1 0.0 1e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.15 KXH45874.1 - 0.00094 17.7 0.8 0.052 11.9 1.8 2.1 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) DHH PF01368.20 KXH45874.1 - 0.02 15.1 0.1 0.034 14.4 0.1 1.4 1 0 0 1 1 1 0 DHH family DUF3425 PF11905.8 KXH45875.1 - 2.5e-17 63.0 0.0 5.1e-17 62.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) Autophagy_act_C PF03987.15 KXH45875.1 - 0.17 12.5 1.6 0.96 10.1 1.4 2.1 2 0 0 2 2 2 0 Autophagocytosis associated protein, active-site domain bZIP_1 PF00170.21 KXH45875.1 - 0.47 10.6 5.3 0.86 9.7 5.3 1.3 1 0 0 1 1 1 0 bZIP transcription factor MFS_1 PF07690.16 KXH45876.1 - 2.7e-31 108.8 34.2 2.7e-31 108.8 34.2 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily GtrA PF04138.14 KXH45876.1 - 3.5 7.9 15.4 2.3 8.5 0.0 4.3 3 2 2 5 5 5 0 GtrA-like protein Fungal_trans_2 PF11951.8 KXH45877.1 - 7.2e-12 44.8 1.2 1.2e-11 44.0 1.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH45877.1 - 8.5e-09 35.4 9.6 1.5e-08 34.6 9.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_M20 PF01546.28 KXH45878.1 - 2.9e-10 40.2 0.4 4.9e-10 39.4 0.4 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KXH45878.1 - 1.4e-07 31.4 0.1 7.1e-07 29.1 0.0 2.3 2 1 0 2 2 2 1 Peptidase dimerisation domain DUF218 PF02698.17 KXH45879.1 - 1.9e-22 79.7 0.0 2.4e-22 79.4 0.0 1.1 1 0 0 1 1 1 1 DUF218 domain Rhodanese PF00581.20 KXH45879.1 - 0.04 14.5 0.0 0.74 10.4 0.0 2.1 1 1 1 2 2 2 0 Rhodanese-like domain Glyco_hydro_3_C PF01915.22 KXH45880.1 - 6.5e-47 160.1 0.0 1.1e-46 159.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KXH45880.1 - 2.4e-36 125.7 0.0 4.6e-36 124.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KXH45880.1 - 5.4e-23 80.9 0.1 9.6e-23 80.1 0.1 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain Lipase_GDSL_2 PF13472.6 KXH45881.1 - 4.3e-17 63.1 0.5 5e-17 62.9 0.5 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KXH45881.1 - 1.3e-10 41.6 0.2 1.6e-10 41.3 0.2 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 KXH45881.1 - 0.0021 18.2 0.0 0.0031 17.7 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family PIG-P PF08510.12 KXH45882.1 - 2.7 7.9 6.1 0.31 11.0 1.8 1.8 2 0 0 2 2 2 0 PIG-P Mito_carr PF00153.27 KXH45883.1 - 1.7e-50 168.9 3.2 7.1e-17 61.1 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KXH45883.1 - 0.036 13.2 1.3 0.097 11.8 0.1 2.2 2 1 0 2 2 2 0 Gammaproteobacterial serine protease DUF3611 PF12263.8 KXH45883.1 - 0.11 12.5 1.5 0.18 11.7 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3611) Collagen PF01391.18 KXH45884.1 - 1.6e-06 27.8 28.8 2.4e-05 24.0 23.3 2.2 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) UCH_1 PF13423.6 KXH45885.1 - 3.2e-100 335.8 0.0 4.6e-100 335.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.24 KXH45885.1 - 3.2e-22 79.8 0.0 5.6e-22 79.0 0.0 1.4 1 0 0 1 1 1 1 Exonuclease UCH PF00443.29 KXH45885.1 - 0.0033 17.0 0.0 0.0063 16.0 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ANAPC4_WD40 PF12894.7 KXH45885.1 - 0.0091 16.3 0.1 5.2 7.4 0.1 3.0 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain LIP1 PF15904.5 KXH45885.1 - 0.037 14.4 0.2 1.4 9.4 0.1 2.7 2 0 0 2 2 2 0 LKB1 serine/threonine kinase interacting protein 1 adh_short_C2 PF13561.6 KXH45886.1 - 9.8e-41 139.8 0.7 3.6e-39 134.7 0.7 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXH45886.1 - 1.3e-35 122.6 0.1 2.7e-35 121.6 0.1 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXH45886.1 - 7.5e-12 45.5 0.1 1.3e-11 44.7 0.1 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KXH45886.1 - 0.019 14.1 0.1 0.04 13.0 0.0 1.5 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Pyr_redox PF00070.27 KXH45886.1 - 0.044 14.4 0.9 0.094 13.3 0.9 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase BUD22 PF09073.10 KXH45887.1 - 1.2e-92 311.6 68.1 4e-91 306.5 68.1 2.2 1 1 0 1 1 1 1 BUD22 Mito_carr PF00153.27 KXH45889.1 - 4.1e-67 222.2 1.2 2.3e-24 85.2 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Antimicrobial_8 PF08103.11 KXH45889.1 - 0.026 14.7 2.4 9.1 6.6 0.1 3.6 3 0 0 3 3 3 0 Uperin family Tim17 PF02466.19 KXH45889.1 - 0.13 12.7 2.6 0.55 10.6 2.6 2.3 1 1 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family RCC1 PF00415.18 KXH45890.1 - 1.7e-19 70.2 1.8 7e-05 23.4 0.0 5.3 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 KXH45890.1 - 4.8e-16 59.0 0.0 3e-08 33.8 0.0 2.5 2 0 0 2 2 2 2 BTB/POZ domain Ank_4 PF13637.6 KXH45890.1 - 4.5e-10 39.9 0.2 3.1e-09 37.2 0.1 2.5 1 1 1 2 2 2 1 Ankyrin repeats (many copies) RCC1_2 PF13540.6 KXH45890.1 - 6.5e-08 32.2 1.0 6.5e-08 32.2 1.0 3.7 3 0 0 3 3 3 1 Regulator of chromosome condensation (RCC1) repeat Ank_2 PF12796.7 KXH45890.1 - 7.7e-07 29.6 0.1 2.3e-06 28.1 0.1 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXH45890.1 - 1.4e-05 25.1 0.2 0.21 12.2 0.0 3.2 2 0 0 2 2 2 2 Ankyrin repeat CysG_dimeriser PF10414.9 KXH45890.1 - 0.029 14.1 0.3 0.11 12.2 0.3 2.0 1 0 0 1 1 1 0 Sirohaem synthase dimerisation region ATG13 PF10033.9 KXH45891.1 - 1.2e-77 260.9 0.0 1.8e-77 260.3 0.0 1.3 1 0 0 1 1 1 1 Autophagy-related protein 13 VHS PF00790.19 KXH45892.1 - 5.3e-36 123.6 0.0 1.2e-35 122.4 0.0 1.6 1 0 0 1 1 1 1 VHS domain SH3_1 PF00018.28 KXH45892.1 - 1.3e-16 59.9 0.1 3.4e-16 58.6 0.1 1.8 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KXH45892.1 - 6.2e-15 54.8 0.9 1.1e-14 54.0 0.1 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 KXH45892.1 - 5.4e-14 51.6 0.0 1.2e-13 50.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain GAT PF03127.14 KXH45892.1 - 4.3e-10 39.8 1.7 4.3e-10 39.8 1.7 1.9 2 0 0 2 2 2 1 GAT domain UIM PF02809.20 KXH45892.1 - 0.0027 17.5 3.3 0.008 16.0 3.3 1.8 1 0 0 1 1 1 1 Ubiquitin interaction motif DUF3361 PF11841.8 KXH45892.1 - 0.23 11.4 0.2 0.46 10.4 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3361) SNF2_N PF00176.23 KXH45893.1 - 2.5e-67 227.1 4.5 2.4e-65 220.6 4.5 2.9 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KXH45893.1 - 1.9e-18 66.8 0.1 2.5e-17 63.2 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXH45893.1 - 2.7e-06 27.5 0.0 7.7e-06 26.0 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KXH45893.1 - 8.6e-06 25.6 0.0 2.3e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase DZR PF12773.7 KXH45893.1 - 0.12 12.4 0.7 0.26 11.3 0.7 1.5 1 0 0 1 1 1 0 Double zinc ribbon PI3K_1B_p101 PF10486.9 KXH45893.1 - 2.3 5.9 6.2 4.1 5.1 6.2 1.3 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Ran-binding PF05508.11 KXH45894.1 - 1.7e-103 345.9 0.0 2.7e-102 341.9 0.0 2.0 1 1 0 1 1 1 1 RanGTP-binding protein GTP_EFTU PF00009.27 KXH45895.1 - 3.2e-43 147.6 0.0 4.9e-43 146.9 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KXH45895.1 - 1.3e-29 102.7 1.3 4.2e-29 101.1 0.0 2.5 3 0 0 3 3 3 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KXH45895.1 - 2.5e-09 37.4 1.9 6.3e-09 36.1 0.6 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KXH45895.1 - 0.0016 18.5 0.1 0.012 15.7 0.1 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase PEPCK_ATP PF01293.20 KXH45896.1 - 8.2e-217 720.4 0.0 9.7e-217 720.2 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_16 PF13191.6 KXH45896.1 - 0.033 14.6 0.0 0.055 13.8 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 KXH45896.1 - 0.18 11.9 0.0 0.34 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain p450 PF00067.22 KXH45898.1 - 7.5e-48 163.4 0.0 9.2e-48 163.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Cupin_8 PF13621.6 KXH45899.1 - 8.9e-27 94.4 0.0 1e-26 94.2 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 KXH45899.1 - 0.001 19.4 0.0 0.022 15.2 0.0 2.5 2 1 0 2 2 2 1 JmjC domain, hydroxylase Cupin_4 PF08007.12 KXH45899.1 - 0.11 12.0 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Cupin superfamily protein CK_II_beta PF01214.18 KXH45900.1 - 4.4e-74 248.2 0.0 8.1e-74 247.4 0.0 1.4 1 1 0 1 1 1 1 Casein kinase II regulatory subunit RRN3 PF05327.11 KXH45900.1 - 0.056 12.0 3.9 0.084 11.4 3.9 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Spt5_N PF11942.8 KXH45900.1 - 1.3 10.1 15.3 0.42 11.6 9.3 2.4 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Pox_Ag35 PF03286.14 KXH45900.1 - 3.7 7.3 9.2 9.6 5.9 5.1 2.2 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Importin_rep_4 PF18808.1 KXH45900.1 - 3.9 7.8 8.5 7.1 7.0 3.1 2.3 2 0 0 2 2 2 0 Importin repeat CENP-B_dimeris PF09026.10 KXH45900.1 - 5.1 7.5 19.0 15 6.0 13.4 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DNA_pol_phi PF04931.13 KXH45900.1 - 9.8 4.1 8.8 16 3.4 8.8 1.3 1 0 0 1 1 1 0 DNA polymerase phi GH43_C2 PF17851.1 KXH45901.1 - 5.3e-22 78.5 0.0 1.5e-21 77.1 0.0 1.7 1 1 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain Glyco_hydro_43 PF04616.14 KXH45901.1 - 1e-16 61.2 6.8 6.3e-13 48.7 2.0 2.3 1 1 1 2 2 2 2 Glycosyl hydrolases family 43 PD40 PF07676.12 KXH45901.1 - 0.077 13.0 2.0 0.31 11.1 0.6 2.7 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Prefoldin PF02996.17 KXH45902.1 - 8e-06 25.8 0.0 1.3e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Prefoldin subunit CLZ PF16526.5 KXH45902.1 - 0.083 13.3 3.4 1.2 9.5 0.7 2.2 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels BST2 PF16716.5 KXH45902.1 - 0.095 13.3 3.5 1.2 9.7 0.0 2.2 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 Trehalose_PPase PF02358.16 KXH45902.1 - 0.1 11.7 0.3 5.2 6.1 0.1 2.1 2 0 0 2 2 2 0 Trehalose-phosphatase DUF3896 PF13035.6 KXH45902.1 - 0.13 12.5 0.9 3 8.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3896) Fzo_mitofusin PF04799.13 KXH45902.1 - 0.26 10.8 2.9 0.48 10.0 0.5 2.0 2 0 0 2 2 2 0 fzo-like conserved region GIT_CC PF16559.5 KXH45902.1 - 0.32 10.9 5.4 0.33 10.9 2.3 2.1 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor tRNA-synt_2b PF00587.25 KXH45903.1 - 2.8e-32 112.2 0.0 1.2e-31 110.1 0.0 1.9 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KXH45903.1 - 2.9e-12 46.6 0.0 6.5e-12 45.4 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain CBF PF03914.17 KXH45904.1 - 1e-49 168.9 0.2 4e-49 166.9 0.2 2.1 1 0 0 1 1 1 1 CBF/Mak21 family Mo25 PF08569.11 KXH45904.1 - 0.068 12.5 0.1 0.12 11.8 0.1 1.3 1 0 0 1 1 1 0 Mo25-like 4HBT PF03061.22 KXH45906.1 - 6.4e-13 48.9 0.1 1.2e-12 47.9 0.1 1.5 1 0 0 1 1 1 1 Thioesterase superfamily APS_kinase PF01583.20 KXH45907.1 - 2.1e-73 245.4 0.0 2.9e-73 245.0 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.6 KXH45907.1 - 5.5e-06 26.6 0.0 1.1e-05 25.6 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KXH45907.1 - 3.2e-05 24.5 0.0 5.3e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 KXH45907.1 - 0.0023 17.5 0.0 0.0029 17.1 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_16 PF13191.6 KXH45907.1 - 0.025 14.9 0.1 0.039 14.3 0.1 1.3 1 1 0 1 1 1 0 AAA ATPase domain PRK PF00485.18 KXH45907.1 - 0.075 12.8 0.0 0.14 11.9 0.0 1.4 1 1 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_29 PF13555.6 KXH45907.1 - 0.084 12.6 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF463 PF04317.12 KXH45907.1 - 0.11 11.5 0.0 0.13 11.2 0.0 1.1 1 0 0 1 1 1 0 YcjX-like family, DUF463 CPT PF07931.12 KXH45907.1 - 0.13 12.1 0.2 0.35 10.7 0.2 2.0 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein G-alpha PF00503.20 KXH45907.1 - 0.18 11.0 0.1 0.28 10.3 0.1 1.3 1 1 0 1 1 1 0 G-protein alpha subunit V-ATPase_C PF03223.15 KXH45908.1 - 2.1e-125 419.0 0.4 2.5e-125 418.7 0.4 1.0 1 0 0 1 1 1 1 V-ATPase subunit C LemA PF04011.12 KXH45908.1 - 0.028 14.3 0.3 0.061 13.2 0.3 1.6 1 0 0 1 1 1 0 LemA family F-box PF00646.33 KXH45910.1 - 1e-08 34.8 2.0 1.3e-08 34.5 0.4 2.0 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KXH45910.1 - 1.4e-06 28.1 2.6 2e-06 27.6 0.2 2.5 3 0 0 3 3 3 1 F-box-like Mod_r PF07200.13 KXH45912.1 - 6.7e-29 100.9 0.5 8.5e-29 100.5 0.5 1.1 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein DUF3524 PF12038.8 KXH45912.1 - 0.028 14.2 0.7 0.045 13.6 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3524) Nup84_Nup100 PF04121.13 KXH45913.1 - 6e-198 659.4 0.4 7.1e-198 659.2 0.4 1.0 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 Rad60-SLD PF11976.8 KXH45914.1 - 4.3e-19 68.1 0.1 5e-19 67.9 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KXH45914.1 - 1.8e-11 43.6 0.1 2.1e-11 43.4 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin family LIM PF00412.22 KXH45915.1 - 5.4e-25 87.4 22.5 6e-09 36.0 6.1 3.5 3 0 0 3 3 3 3 LIM domain DUF2321 PF10083.9 KXH45915.1 - 0.0085 15.7 0.3 0.0085 15.7 0.3 3.2 2 1 1 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2321) zf-dskA_traR PF01258.17 KXH45915.1 - 0.034 14.1 0.2 0.034 14.1 0.2 5.9 7 0 0 7 7 7 0 Prokaryotic dksA/traR C4-type zinc finger Pet191_N PF10203.9 KXH45916.1 - 0.0044 17.3 1.1 0.0071 16.6 1.1 1.4 1 1 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 CHCH PF06747.13 KXH45916.1 - 0.021 14.9 0.1 0.047 13.8 0.1 1.6 1 0 0 1 1 1 0 CHCH domain Dynamin_M PF01031.20 KXH45917.1 - 1.8e-109 365.4 0.0 3.2e-109 364.6 0.0 1.4 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 KXH45917.1 - 6.6e-57 192.2 0.0 1.3e-56 191.3 0.0 1.5 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 KXH45917.1 - 1.6e-30 105.1 1.6 1.6e-30 105.1 1.6 2.2 3 0 0 3 3 3 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KXH45917.1 - 4.3e-05 23.6 0.3 0.00056 20.0 0.3 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase F-box PF00646.33 KXH45918.1 - 0.0058 16.5 0.0 0.017 15.0 0.0 1.8 1 0 0 1 1 1 1 F-box domain PWI PF01480.17 KXH45919.1 - 7.2e-13 48.7 0.2 1.1e-12 48.0 0.2 1.3 1 0 0 1 1 1 1 PWI domain SOG2 PF10428.9 KXH45919.1 - 0.005 16.1 11.6 0.006 15.9 11.6 1.1 1 0 0 1 1 1 1 RAM signalling pathway protein SOBP PF15279.6 KXH45919.1 - 2.9 8.4 9.7 4.7 7.7 9.7 1.4 1 0 0 1 1 1 0 Sine oculis-binding protein Nas2_N PF18265.1 KXH45920.1 - 7.6e-10 38.6 4.8 3.6e-07 30.0 0.7 2.3 1 1 1 2 2 2 2 Nas2 N_terminal domain PDZ_6 PF17820.1 KXH45920.1 - 4.9e-08 32.7 0.0 1e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 KXH45920.1 - 3.1e-05 24.2 0.0 5.8e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KXH45920.1 - 0.00015 22.1 0.0 0.00029 21.1 0.0 1.5 1 0 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.14 KXH45920.1 - 0.0058 17.0 0.0 0.014 15.7 0.0 1.6 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain DUF5136 PF17199.4 KXH45920.1 - 0.03 14.0 0.1 0.066 12.9 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF5136) HAUS-augmin3 PF14932.6 KXH45920.1 - 0.073 12.6 0.1 0.11 12.0 0.1 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF1192 PF06698.11 KXH45920.1 - 0.081 13.0 0.1 0.2 11.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) CENP-K PF11802.8 KXH45920.1 - 0.083 12.4 1.2 0.35 10.4 1.4 1.7 1 1 1 2 2 2 0 Centromere-associated protein K Ras PF00071.22 KXH45921.1 - 4.3e-49 166.2 0.0 5.2e-49 166.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXH45921.1 - 1e-29 103.2 0.1 2.6e-29 101.9 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXH45921.1 - 2.1e-10 40.3 0.0 2.7e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KXH45921.1 - 0.00029 20.9 0.0 0.00054 20.0 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase RNA_helicase PF00910.22 KXH45921.1 - 0.00049 20.5 0.1 0.0029 18.0 0.1 2.1 1 1 0 1 1 1 1 RNA helicase Gtr1_RagA PF04670.12 KXH45921.1 - 0.0028 17.0 0.0 0.0037 16.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Pox_A32 PF04665.12 KXH45921.1 - 0.018 14.5 0.1 0.033 13.7 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_7 PF12775.7 KXH45921.1 - 0.023 14.2 0.1 0.037 13.5 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region RsgA_GTPase PF03193.16 KXH45921.1 - 0.03 14.2 0.1 9 6.2 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase G-alpha PF00503.20 KXH45921.1 - 0.041 13.0 2.8 1.5 7.9 0.2 2.6 2 1 1 3 3 3 0 G-protein alpha subunit AAA_24 PF13479.6 KXH45921.1 - 0.057 13.1 0.3 0.095 12.4 0.2 1.4 1 1 0 1 1 1 0 AAA domain SRPRB PF09439.10 KXH45921.1 - 0.081 12.4 0.0 0.13 11.7 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 KXH45921.1 - 0.082 13.3 0.1 0.2 12.0 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_33 PF13671.6 KXH45921.1 - 0.097 12.8 0.2 0.2 11.8 0.2 1.5 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KXH45921.1 - 0.13 12.3 0.2 0.28 11.2 0.2 1.6 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Septin PF00735.18 KXH45921.1 - 0.15 11.3 0.5 0.22 10.8 0.0 1.6 2 0 0 2 2 2 0 Septin ATPase PF06745.13 KXH45921.1 - 0.21 10.9 0.2 0.31 10.4 0.2 1.2 1 0 0 1 1 1 0 KaiC Homeodomain PF00046.29 KXH45922.1 - 3.3e-13 49.2 1.0 7.2e-13 48.2 1.0 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KXH45922.1 - 0.063 13.2 0.2 0.2 11.6 0.2 1.8 1 0 0 1 1 1 0 Homeobox KN domain NAD_kinase PF01513.21 KXH45923.1 - 1.3e-82 277.3 0.0 2.2e-82 276.6 0.0 1.3 1 0 0 1 1 1 1 ATP-NAD kinase SNO PF01174.19 KXH45977.1 - 8.2e-52 175.8 0.0 1.4e-40 139.1 0.0 2.1 1 1 1 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.14 KXH45977.1 - 9.6e-08 31.9 0.0 3.4e-07 30.0 0.0 1.8 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain DJ-1_PfpI PF01965.24 KXH45977.1 - 0.00014 21.7 0.0 0.00028 20.8 0.0 1.5 1 0 0 1 1 1 1 DJ-1/PfpI family Peptidase_S51 PF03575.17 KXH45977.1 - 0.00045 19.9 0.0 0.00065 19.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family S51 GATase PF00117.28 KXH45977.1 - 0.00056 19.7 0.0 0.0067 16.2 0.0 2.0 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Candida_ALS PF05792.13 KXH45979.1 - 8.5e-23 80.6 200.0 1.3e-06 28.8 6.5 178.9 180 4 0 180 180 180 95 Candida agglutinin-like (ALS) DUF1905 PF08922.11 KXH45979.1 - 0.077 13.1 29.0 14 5.9 0.1 12.1 6 3 6 12 12 12 0 Domain of unknown function (DUF1905) DUF1645 PF07816.11 KXH45980.1 - 0.05 14.2 4.5 0.12 12.9 4.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1645) UDPGT PF00201.18 KXH45981.1 - 1.1e-13 50.8 0.0 1.6e-13 50.3 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Ribosomal_L36e PF01158.18 KXH45981.1 - 0.0077 16.4 0.1 0.014 15.6 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L36e Pyr_redox_3 PF13738.6 KXH45982.1 - 1.9e-18 66.8 0.0 1.6e-17 63.7 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KXH45982.1 - 3.8e-16 58.6 0.0 2.4e-14 52.7 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KXH45982.1 - 1.4e-13 50.8 0.0 9.2e-11 41.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXH45982.1 - 2.1e-13 50.1 0.0 2.7e-11 43.2 0.0 2.2 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Shikimate_DH PF01488.20 KXH45982.1 - 0.0001 22.4 0.1 0.0028 17.7 0.0 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.6 KXH45982.1 - 0.019 14.9 0.1 0.47 10.4 0.0 2.6 2 1 1 3 3 3 0 FAD-NAD(P)-binding Pyr_redox PF00070.27 KXH45982.1 - 0.059 13.9 0.1 14 6.3 0.0 3.2 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase ADH_N PF08240.12 KXH45983.1 - 1.5e-31 108.5 2.9 1.5e-31 108.5 0.5 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXH45983.1 - 2.2e-19 69.7 0.1 4.2e-19 68.8 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXH45983.1 - 0.0012 19.9 0.0 0.0022 19.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pyr_redox_2 PF07992.14 KXH45983.1 - 0.0048 16.2 0.2 0.0079 15.5 0.2 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Glu_dehyd_C PF16912.5 KXH45983.1 - 0.0059 16.1 1.3 0.013 15.0 1.3 1.7 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus 2-Hacid_dh_C PF02826.19 KXH45983.1 - 0.0062 15.9 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_25 PF13649.6 KXH45983.1 - 0.049 14.4 0.2 0.14 12.9 0.1 1.7 1 1 0 1 1 1 0 Methyltransferase domain AdoHcyase_NAD PF00670.21 KXH45983.1 - 0.065 13.3 0.1 0.14 12.2 0.1 1.5 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 KXH45983.1 - 0.072 12.7 0.1 0.12 12.0 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Hexapep PF00132.24 KXH45983.1 - 0.072 12.8 0.9 0.21 11.4 0.9 1.7 1 0 0 1 1 1 0 Bacterial transferase hexapeptide (six repeats) DUF4375 PF14300.6 KXH45984.1 - 0.024 14.9 0.0 0.13 12.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4375) DivIVA PF05103.13 KXH45984.1 - 0.041 14.0 1.3 0.57 10.3 0.7 2.3 2 0 0 2 2 2 0 DivIVA protein Moulting_cycle PF04870.16 KXH45984.1 - 0.057 12.7 4.2 0.097 11.9 4.2 1.3 1 0 0 1 1 1 0 Moulting cycle Zn_clus PF00172.18 KXH45985.1 - 2.3e-09 37.2 9.2 3.5e-09 36.6 9.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXH45985.1 - 0.00012 21.2 0.1 0.00044 19.4 0.1 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain TMEM171 PF15471.6 KXH45985.1 - 7.9 5.4 8.3 15 4.5 8.3 1.4 1 0 0 1 1 1 0 Transmembrane protein family 171 Glyco_hydro_7 PF00840.20 KXH45986.1 - 2.1e-183 610.0 17.0 2.4e-183 609.8 17.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 DUF2841 PF11001.8 KXH45987.1 - 1.8e-43 147.5 6.9 3e-43 146.8 6.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) GRP PF07172.11 KXH45987.1 - 3.1 8.5 5.4 8 7.2 5.4 1.7 1 0 0 1 1 1 0 Glycine rich protein family ABC_membrane PF00664.23 KXH45988.1 - 2.4e-93 312.8 22.6 2.6e-48 165.0 5.7 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KXH45988.1 - 1.7e-50 171.1 0.0 9.5e-31 107.1 0.1 2.8 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KXH45988.1 - 1.6e-09 37.5 4.3 0.0056 16.1 0.1 4.3 2 2 0 4 4 4 3 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KXH45988.1 - 1.4e-06 28.4 0.1 0.059 13.4 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KXH45988.1 - 8.3e-05 22.5 0.1 0.1 12.5 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase UPF0093 PF03653.13 KXH45988.1 - 0.0014 18.8 1.4 0.0042 17.3 0.3 2.3 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0093) Dynamin_N PF00350.23 KXH45988.1 - 0.0017 18.4 3.1 0.067 13.2 0.0 3.0 3 0 0 3 3 3 1 Dynamin family AAA_16 PF13191.6 KXH45988.1 - 0.0025 18.2 2.0 0.066 13.6 0.1 2.8 3 0 0 3 3 2 1 AAA ATPase domain AAA_29 PF13555.6 KXH45988.1 - 0.0066 16.2 0.3 2.8 7.7 0.0 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain ABC_membrane_2 PF06472.15 KXH45988.1 - 0.0069 15.8 0.1 0.032 13.7 0.1 2.1 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 AAA_23 PF13476.6 KXH45988.1 - 0.021 15.3 1.0 3.8 7.9 0.0 3.3 4 0 0 4 4 4 0 AAA domain AAA_21 PF13304.6 KXH45988.1 - 0.047 13.5 0.4 8.8 6.0 0.0 2.8 2 1 1 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF87 PF01935.17 KXH45988.1 - 0.093 12.8 2.8 1.1 9.3 0.1 2.7 3 0 0 3 3 2 0 Helicase HerA, central domain AAA_15 PF13175.6 KXH45988.1 - 0.094 12.4 0.3 2.7 7.6 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain IstB_IS21 PF01695.17 KXH45988.1 - 0.12 12.1 0.0 2.3 7.9 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein AIG1 PF04548.16 KXH45988.1 - 0.24 10.7 0.8 5.6 6.2 0.0 2.4 2 0 0 2 2 2 0 AIG1 family AAA_30 PF13604.6 KXH45988.1 - 0.26 11.0 3.0 1.7 8.3 0.0 2.9 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KXH45988.1 - 0.48 10.7 2.3 58 4.0 0.6 3.4 2 1 0 2 2 2 0 AAA domain MWFE PF15879.5 KXH45988.1 - 1.8 8.8 3.8 1.3 9.3 0.4 2.7 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase MWFE subunit Fungal_trans_2 PF11951.8 KXH45989.1 - 0.0042 16.0 0.0 0.005 15.7 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 KXH45990.1 - 3.5e-27 95.3 6.1 4.1e-27 95.0 6.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH45990.1 - 4.8e-12 45.5 6.4 6.8e-12 45.0 6.4 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH45991.1 - 3.8e-14 52.4 13.1 3.8e-14 52.4 13.1 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily TMEM252 PF15664.5 KXH45991.1 - 0.21 11.3 0.0 0.38 10.5 0.0 1.4 1 0 0 1 1 1 0 Transmembrane protein 252 family DUF202 PF02656.15 KXH45991.1 - 2 8.9 10.1 2.3 8.7 0.3 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF202) DUF3669 PF12417.8 KXH45992.1 - 1.1e-18 67.2 0.4 1.1e-18 67.2 0.4 1.9 2 0 0 2 2 2 1 Zinc finger protein SH3_16 PF18348.1 KXH45993.1 - 0.068 13.0 0.5 0.35 10.7 0.6 2.1 2 0 0 2 2 2 0 Bacterial dipeptidyl-peptidase Sh3 domain GREB1 PF15782.5 KXH45994.1 - 4.2 4.4 5.9 4.8 4.2 5.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer CRIM PF16978.5 KXH45995.1 - 2.3e-46 157.5 0.0 1e-45 155.4 0.0 2.0 2 0 0 2 2 2 1 SAPK-interacting protein 1 (Sin1), middle CRIM domain SIN1_PH PF16979.5 KXH45995.1 - 1.2e-24 86.7 1.2 2.5e-24 85.6 1.2 1.6 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology PH PF00169.29 KXH45995.1 - 0.012 16.2 0.1 0.023 15.2 0.1 1.5 1 0 0 1 1 1 0 PH domain TUG-UBL1 PF11470.8 KXH45995.1 - 0.012 15.8 0.0 0.028 14.6 0.0 1.5 1 0 0 1 1 1 0 TUG ubiquitin-like domain PBP1_TM PF14812.6 KXH45995.1 - 1.4 9.4 11.6 0.2 12.1 2.4 3.3 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PRCC PF10253.9 KXH45996.1 - 1.9e-38 133.4 12.5 1.9e-38 133.4 12.5 2.2 1 1 0 2 2 2 1 Mitotic checkpoint regulator, MAD2B-interacting HLH PF00010.26 KXH45997.1 - 0.11 12.4 0.0 0.29 11.1 0.0 1.6 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain DUF3517 PF12030.8 KXH45998.1 - 2.1e-95 319.5 1.7 2.1e-95 319.5 1.7 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3517) UCH PF00443.29 KXH45998.1 - 2.9e-39 135.1 0.0 6.7e-39 133.9 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KXH45998.1 - 2.8e-20 73.1 0.0 6.2e-20 72.0 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Pox_A3L PF05288.11 KXH45998.1 - 0.0042 17.0 0.0 0.02 14.9 0.0 2.3 1 0 0 1 1 1 1 Poxvirus A3L Protein RNase_P_pop3 PF08228.11 KXH45999.1 - 4e-07 30.2 0.0 5.3e-05 23.3 0.0 2.2 2 0 0 2 2 2 2 RNase P subunit Pop3 Hemolysin_N PF12563.8 KXH45999.1 - 0.12 11.9 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Hemolytic toxin N terminal NOC3p PF07540.11 KXH46001.1 - 1.3e-29 102.5 0.6 1.8e-28 98.8 0.2 2.8 2 0 0 2 2 2 1 Nucleolar complex-associated protein CBF PF03914.17 KXH46001.1 - 6.7e-25 88.1 1.9 9e-25 87.7 0.6 2.0 2 0 0 2 2 2 1 CBF/Mak21 family UPF0113_N PF17833.1 KXH46002.1 - 5e-26 91.1 0.0 6.8e-26 90.7 0.0 1.2 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 KXH46002.1 - 3.9e-24 84.7 0.0 2.2e-23 82.3 0.0 2.0 2 0 0 2 2 2 1 UPF0113 PUA domain Glyco_trans_2_3 PF13632.6 KXH46003.1 - 1.4e-49 168.7 5.3 4e-49 167.2 5.3 1.8 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 KXH46003.1 - 1.1e-05 25.3 0.0 3.5e-05 23.7 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 KXH46003.1 - 0.00029 20.4 0.0 0.00055 19.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 KXH46003.1 - 0.005 16.8 0.1 0.0087 16.0 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Pro-kuma_activ PF09286.11 KXH46005.1 - 9.2e-38 129.7 0.1 2.1e-37 128.5 0.1 1.7 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KXH46005.1 - 0.00015 21.1 0.1 0.00026 20.4 0.1 1.2 1 0 0 1 1 1 1 Subtilase family BBP1_C PF15272.6 KXH46007.1 - 0.038 13.8 0.4 0.038 13.8 0.4 2.2 3 0 0 3 3 3 0 Spindle pole body component BBP1, C-terminal Methyltransf_31 PF13847.6 KXH46009.1 - 2.3e-15 56.7 0.0 9.7e-14 51.4 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH46009.1 - 5.2e-09 36.7 0.1 1.9e-07 31.7 0.1 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXH46009.1 - 6.2e-09 35.9 0.3 1.9e-08 34.3 0.3 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH46009.1 - 4.1e-08 33.9 0.0 1.2e-07 32.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH46009.1 - 1.8e-07 31.7 0.8 9.2e-06 26.2 0.1 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.6 KXH46009.1 - 1.1e-05 25.5 0.0 1.3e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain AdoMet_MTase PF07757.13 KXH46009.1 - 0.00028 21.2 0.0 0.00051 20.4 0.0 1.4 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase MTS PF05175.14 KXH46009.1 - 0.0013 18.3 0.0 0.002 17.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain MetW PF07021.12 KXH46009.1 - 0.0039 16.8 0.0 0.0066 16.1 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW PrmA PF06325.13 KXH46009.1 - 0.018 14.5 0.0 0.023 14.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) HEAT PF02985.22 KXH46010.1 - 1.3e-38 127.7 15.0 0.015 15.5 0.1 13.2 14 0 0 14 14 14 10 HEAT repeat HEAT_2 PF13646.6 KXH46010.1 - 4.1e-34 116.8 4.9 3.2e-11 43.5 0.0 8.2 4 2 5 9 9 9 8 HEAT repeats HEAT_EZ PF13513.6 KXH46010.1 - 1.9e-12 47.4 4.8 0.044 14.3 0.1 7.6 8 1 1 9 9 8 2 HEAT-like repeat Cnd1 PF12717.7 KXH46010.1 - 3.2e-11 43.5 11.9 0.0004 20.5 0.2 6.3 5 1 0 7 7 7 4 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 KXH46010.1 - 2.8e-10 40.7 5.9 0.048 14.3 0.1 7.9 5 1 3 9 9 9 1 Vacuolar 14 Fab1-binding region RTP1_C1 PF10363.9 KXH46010.1 - 3.5e-06 27.1 6.0 0.2 11.8 0.2 5.2 4 1 1 5 5 5 2 Required for nuclear transport of RNA pol II C-terminus 1 Adaptin_N PF01602.20 KXH46010.1 - 2.5e-05 23.1 12.1 0.0074 14.9 0.1 5.1 2 1 2 4 4 4 3 Adaptin N terminal region CLASP_N PF12348.8 KXH46010.1 - 0.00037 20.1 2.4 1.9 8.0 0.1 4.6 2 2 3 5 5 5 1 CLASP N terminal M11L PF11099.8 KXH46010.1 - 0.033 14.5 0.4 3.7 7.8 0.0 3.4 2 1 0 3 3 3 0 Apoptosis regulator M11L like Proteasom_PSMB PF10508.9 KXH46010.1 - 0.065 11.7 5.4 0.34 9.4 0.1 2.5 2 1 0 2 2 2 0 Proteasome non-ATPase 26S subunit Ecm29 PF13001.7 KXH46010.1 - 0.09 11.4 4.1 1.2 7.7 0.0 3.6 4 1 0 5 5 5 0 Proteasome stabiliser Arm PF00514.23 KXH46010.1 - 0.8 9.8 5.4 28 4.9 0.0 4.8 7 0 0 7 7 7 0 Armadillo/beta-catenin-like repeat tRNA_synthFbeta PF17759.1 KXH46011.1 - 8.3e-46 156.1 0.0 1.3e-45 155.5 0.0 1.3 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 KXH46011.1 - 2.6e-31 107.7 0.8 1.8e-30 105.0 0.1 2.5 2 1 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 KXH46011.1 - 7.1e-27 94.2 0.1 1.2e-26 93.5 0.1 1.4 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 KXH46011.1 - 4.6e-16 58.9 0.0 2.4e-13 50.2 0.0 2.6 2 0 0 2 2 2 2 tRNA synthetase B5 domain Myotub-related PF06602.14 KXH46013.1 - 9.6e-148 491.8 0.1 1.2e-147 491.5 0.1 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase PF00102.27 KXH46013.1 - 0.0074 15.9 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 KXH46013.1 - 0.13 12.2 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family Ribosomal_S3_C PF00189.20 KXH46014.1 - 8.5e-25 87.1 0.2 4.4e-24 84.8 0.1 2.1 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 KXH46014.1 - 6.6e-12 45.1 0.1 1.1e-11 44.4 0.1 1.4 1 0 0 1 1 1 1 KH domain Coilin_N PF15862.5 KXH46014.1 - 0.089 12.6 1.0 0.33 10.8 0.0 2.0 2 0 0 2 2 2 0 Coilin N-terminus UN_NPL4 PF11543.8 KXH46014.1 - 0.1 13.1 0.0 0.2 12.2 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Mg_trans_NIPA PF05653.14 KXH46015.1 - 2.1e-100 335.7 14.8 2.5e-100 335.4 14.8 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 KXH46015.1 - 0.00014 22.1 6.2 0.00014 22.1 6.2 3.3 3 0 0 3 3 3 2 EamA-like transporter family DUF2420 PF10336.9 KXH46016.1 - 7.9e-08 32.3 0.0 0.01 15.8 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF2420) Adap_comp_sub PF00928.21 KXH46017.1 - 1.7e-17 63.7 0.1 2.5e-17 63.1 0.1 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KXH46017.1 - 3.5e-08 33.5 0.1 5.9e-08 32.8 0.1 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain BBP2_2 PF10082.9 KXH46017.1 - 0.00053 18.9 0.1 0.00084 18.3 0.1 1.2 1 0 0 1 1 1 1 Putative beta-barrel porin 2 RPM2 PF08579.11 KXH46017.1 - 0.0075 16.7 0.3 0.015 15.7 0.3 1.5 1 0 0 1 1 1 1 Mitochondrial ribonuclease P subunit (RPM2) ANAPC4 PF12896.7 KXH46018.1 - 4.8e-68 228.7 0.0 7.6e-68 228.0 0.0 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 ANAPC4_WD40 PF12894.7 KXH46018.1 - 1.5e-10 41.2 0.0 9.7e-10 38.6 0.0 2.4 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KXH46018.1 - 0.033 15.1 0.0 0.5 11.3 0.0 3.0 2 0 0 2 2 2 0 WD domain, G-beta repeat HNH_2 PF13391.6 KXH46019.1 - 5.4e-12 45.7 0.0 1.5e-11 44.3 0.0 1.8 2 0 0 2 2 2 1 HNH endonuclease Gtr1_RagA PF04670.12 KXH46020.1 - 3.3e-70 236.0 0.1 4.1e-70 235.7 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 KXH46020.1 - 0.02 15.1 0.0 0.042 14.1 0.0 1.6 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 KXH46020.1 - 0.022 14.3 0.0 0.039 13.5 0.0 1.3 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 KXH46020.1 - 0.033 14.6 0.0 0.081 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain MMR_HSR1 PF01926.23 KXH46020.1 - 0.12 12.4 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase MIF PF01187.18 KXH46021.1 - 7e-10 39.2 0.0 1.1e-09 38.5 0.0 1.3 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) TFIIIC_delta PF12657.7 KXH46026.1 - 2.7e-15 56.8 0.0 1.4e-14 54.5 0.0 2.2 2 0 0 2 2 2 1 Transcription factor IIIC subunit delta N-term zf-TFIIIC PF12660.7 KXH46026.1 - 2e-10 40.5 3.0 1e-09 38.2 2.8 2.1 2 0 0 2 2 2 1 Putative zinc-finger of transcription factor IIIC complex Methyltransf_25 PF13649.6 KXH46027.1 - 8.2e-22 77.7 0.0 1.8e-21 76.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH46027.1 - 6.9e-18 65.1 0.0 1.4e-17 64.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH46027.1 - 3.3e-14 52.9 0.0 6e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH46027.1 - 1e-13 51.8 0.0 2.6e-13 50.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXH46027.1 - 1.3e-10 41.3 0.0 2.2e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXH46027.1 - 4.2e-10 39.4 0.0 5.5e-10 39.0 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KXH46027.1 - 4.3e-08 32.9 0.0 8.7e-08 31.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_PK PF05891.12 KXH46027.1 - 1.8e-07 30.9 0.0 4.3e-07 29.7 0.0 1.4 1 1 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_2 PF00891.18 KXH46027.1 - 1.3e-06 27.9 0.0 2.2e-06 27.2 0.0 1.3 1 1 0 1 1 1 1 O-methyltransferase domain CMAS PF02353.20 KXH46027.1 - 8.9e-06 25.2 0.0 1.2e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase CheR PF01739.18 KXH46027.1 - 2.3e-05 24.0 0.0 0.0005 19.6 0.0 2.3 1 1 1 2 2 2 1 CheR methyltransferase, SAM binding domain NodS PF05401.11 KXH46027.1 - 0.00018 21.2 0.0 0.00023 20.9 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) TehB PF03848.14 KXH46027.1 - 0.00099 18.6 0.0 0.0014 18.0 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_16 PF10294.9 KXH46027.1 - 0.0017 18.1 0.0 0.0028 17.4 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase PCMT PF01135.19 KXH46027.1 - 0.0043 16.8 0.0 0.0063 16.3 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF2608 PF11019.8 KXH46027.1 - 0.0096 15.4 0.0 0.024 14.1 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2608) UPF0020 PF01170.18 KXH46027.1 - 0.028 14.1 0.0 0.13 11.9 0.0 1.9 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 Methyltransf_4 PF02390.17 KXH46027.1 - 0.038 13.5 0.0 0.1 12.1 0.0 1.7 1 1 0 1 1 1 0 Putative methyltransferase His_Phos_1 PF00300.22 KXH46028.1 - 4.3e-07 29.8 1.2 0.16 11.6 0.0 3.9 3 1 1 4 4 4 3 Histidine phosphatase superfamily (branch 1) Mito_carr PF00153.27 KXH46029.1 - 2.1e-55 184.6 3.9 1.3e-18 66.6 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Cation_efflux PF01545.21 KXH46030.1 - 3.8e-47 160.6 4.4 5.2e-47 160.2 4.4 1.2 1 0 0 1 1 1 1 Cation efflux family Glyco_trans_1_4 PF13692.6 KXH46031.1 - 1.3e-07 32.2 0.0 5.6e-07 30.1 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 KXH46031.1 - 9.6e-06 25.2 0.0 1.8e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 KXH46031.1 - 0.0041 17.5 0.0 0.0091 16.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 APH PF01636.23 KXH46032.1 - 1.4e-15 57.9 0.0 6.4e-15 55.7 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.20 KXH46032.1 - 0.14 11.5 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase p450 PF00067.22 KXH46034.1 - 4.9e-55 187.1 0.0 6e-55 186.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Actin PF00022.19 KXH46059.1 - 1.9e-98 329.7 0.0 1.9e-97 326.5 0.0 1.9 1 1 0 1 1 1 1 Actin Cupin_1 PF00190.22 KXH46060.1 - 7.7e-21 74.3 0.8 9.9e-21 73.9 0.8 1.1 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.11 KXH46060.1 - 4.3e-06 26.3 0.0 7.3e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Cupin domain MannoseP_isomer PF01050.18 KXH46060.1 - 0.13 12.2 0.0 0.17 11.7 0.0 1.1 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase F-box PF00646.33 KXH46061.1 - 0.05 13.5 0.0 0.22 11.4 0.1 2.1 2 1 1 3 3 3 0 F-box domain MIT PF04212.18 KXH46061.1 - 0.22 11.6 0.0 0.44 10.7 0.0 1.4 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain UFD1 PF03152.14 KXH46062.1 - 6.6e-27 94.1 0.0 1.9e-21 76.3 0.0 3.6 3 1 0 3 3 3 2 Ubiquitin fusion degradation protein UFD1 AZUL PF16558.5 KXH46062.1 - 1.3e-06 28.5 0.0 5.1e-06 26.6 0.0 2.0 1 0 0 1 1 1 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A DUF5413 PF17434.2 KXH46063.1 - 0.02 15.2 0.4 0.033 14.5 0.4 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5413) His_Phos_2 PF00328.22 KXH46065.1 - 2.8e-31 109.3 0.0 5.4e-31 108.3 0.0 1.4 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) BNR_2 PF13088.6 KXH46066.1 - 0.021 14.1 0.0 0.47 9.7 0.0 2.2 1 1 2 3 3 3 0 BNR repeat-like domain BNR PF02012.20 KXH46066.1 - 0.094 12.8 0.6 20 5.7 0.1 3.3 2 0 0 2 2 2 0 BNR/Asp-box repeat Amidohydro_2 PF04909.14 KXH46067.1 - 2.1e-36 126.2 0.3 2.7e-36 125.8 0.3 1.1 1 0 0 1 1 1 1 Amidohydrolase DUF4027 PF13219.6 KXH46067.1 - 0.19 11.6 0.1 0.38 10.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4027) Fungal_trans PF04082.18 KXH46068.1 - 5.2e-10 38.8 0.1 9.5e-10 37.9 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH46068.1 - 3.3e-05 23.9 8.1 8.4e-05 22.6 8.1 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CPSF73-100_C PF11718.8 KXH46068.1 - 0.17 11.4 0.0 0.31 10.5 0.0 1.4 1 0 0 1 1 1 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term PLDc_N PF13396.6 KXH46070.1 - 2e-11 43.6 3.4 2e-11 43.6 3.4 1.5 2 0 0 2 2 2 1 Phospholipase_D-nuclease N-terminal DUF2207 PF09972.9 KXH46070.1 - 0.047 12.4 0.7 0.055 12.2 0.7 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Pox_A14 PF05767.12 KXH46070.1 - 0.06 13.5 0.2 0.095 12.9 0.2 1.3 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 OPT PF03169.15 KXH46071.1 - 1.9e-40 139.1 2.8 2.3e-40 138.8 2.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF3054 PF11255.8 KXH46071.1 - 0.37 11.3 7.9 1.5 9.3 2.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3054) Aminotran_5 PF00266.19 KXH46072.1 - 5.5e-08 32.2 0.0 4.5e-07 29.2 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KXH46072.1 - 0.013 14.8 0.0 0.02 14.2 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 KXH46072.1 - 0.18 10.9 0.0 1.2 8.2 0.0 2.1 2 0 0 2 2 2 0 Aminotransferase class I and II IDO PF01231.18 KXH46073.1 - 2.6e-152 507.6 0.0 3e-152 507.4 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase DUF1864 PF08933.11 KXH46073.1 - 4.6e-05 22.4 0.1 0.0026 16.6 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF1864) Zn_clus PF00172.18 KXH46074.1 - 2e-07 31.0 13.7 3.4e-07 30.3 13.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXH46074.1 - 3.8e-07 29.4 0.0 6.5e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.18 KXH46075.1 - 9.8e-20 70.7 0.8 1.4e-19 70.2 0.8 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_31 PF01055.26 KXH46076.1 - 3.9e-64 217.5 1.3 5.3e-64 217.0 1.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 ATS3 PF06232.11 KXH46076.1 - 0.054 13.4 0.6 4.5 7.2 0.0 2.9 3 0 0 3 3 3 0 Embryo-specific protein 3, (ATS3) Aldedh PF00171.22 KXH46082.1 - 2.7e-186 619.6 0.4 3e-186 619.4 0.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family p450 PF00067.22 KXH46083.1 - 1.1e-55 189.2 0.0 1.5e-55 188.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KXH46084.1 - 2.9e-58 197.7 0.0 3.6e-58 197.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CDI PF02234.19 KXH46084.1 - 0.082 13.1 0.1 0.24 11.6 0.1 1.8 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor FAD_binding_4 PF01565.23 KXH46085.1 - 8.8e-28 96.8 0.3 3e-27 95.1 0.2 1.8 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 KXH46085.1 - 6.7e-06 26.1 0.2 1.7e-05 24.8 0.2 1.7 1 0 0 1 1 1 1 Berberine and berberine like ketoacyl-synt PF00109.26 KXH46086.1 - 1.6e-70 237.6 0.0 3.3e-70 236.6 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KXH46086.1 - 5.1e-56 189.4 0.0 1.4e-55 188.0 0.0 1.8 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 KXH46086.1 - 5.4e-54 183.4 0.0 1.1e-53 182.4 0.0 1.6 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 KXH46086.1 - 5.1e-48 164.2 0.1 1.2e-47 163.0 0.0 1.7 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KXH46086.1 - 2.7e-37 127.4 0.1 7.3e-37 126.0 0.1 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 KXH46086.1 - 6.2e-21 75.0 0.0 4e-20 72.4 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain ADH_zinc_N_2 PF13602.6 KXH46086.1 - 4.3e-19 69.9 0.0 1.4e-17 65.0 0.0 2.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KXH46086.1 - 5.8e-18 65.1 2.2 9.9e-17 61.1 0.0 3.7 4 0 0 4 4 4 1 Zinc-binding dehydrogenase KAsynt_C_assoc PF16197.5 KXH46086.1 - 3e-14 53.4 0.0 1.2e-13 51.5 0.0 2.1 1 1 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_25 PF13649.6 KXH46086.1 - 9.2e-14 51.9 0.0 6e-13 49.3 0.0 2.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXH46086.1 - 1.3e-12 47.8 0.0 3e-12 46.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH46086.1 - 7.2e-12 45.3 0.0 3.3e-11 43.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH46086.1 - 8.2e-11 42.4 0.0 3.2e-10 40.5 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 KXH46086.1 - 4.8e-08 33.2 0.0 1.5e-07 31.7 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.25 KXH46086.1 - 2.3e-07 30.5 3.4 1.1e-06 28.2 0.0 3.0 3 0 0 3 3 3 1 short chain dehydrogenase Thiolase_N PF00108.23 KXH46086.1 - 3.8e-06 26.4 0.1 8.5e-06 25.3 0.1 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain DUF938 PF06080.12 KXH46086.1 - 5.9e-05 22.9 0.0 0.001 18.9 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF938) Ubie_methyltran PF01209.18 KXH46086.1 - 7.7e-05 22.1 0.0 0.00022 20.6 0.0 1.7 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family ADH_N PF08240.12 KXH46086.1 - 9.1e-05 22.3 0.0 0.00028 20.8 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain adh_short_C2 PF13561.6 KXH46086.1 - 0.00056 19.5 0.3 0.0025 17.4 0.0 2.2 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Methyltransf_28 PF02636.17 KXH46086.1 - 0.0059 16.3 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_33 PF10017.9 KXH46086.1 - 0.018 14.2 0.0 0.046 12.9 0.0 1.6 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent Methyltransf_24 PF13578.6 KXH46086.1 - 0.04 14.9 0.0 0.13 13.3 0.0 2.0 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.9 KXH46086.1 - 0.043 13.6 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 Lysine methyltransferase PALP PF00291.25 KXH46086.1 - 0.081 12.3 1.2 0.18 11.2 0.1 2.2 2 0 0 2 2 1 0 Pyridoxal-phosphate dependent enzyme ACP_syn_III PF08545.10 KXH46086.1 - 0.12 12.3 0.3 0.33 10.8 0.3 1.8 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DUF915 PF06028.11 KXH46086.1 - 0.12 11.7 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) DREV PF05219.12 KXH46086.1 - 0.14 11.2 0.0 0.31 10.1 0.0 1.5 1 0 0 1 1 1 0 DREV methyltransferase Glyco_hydro_47 PF01532.20 KXH46087.1 - 1.5e-166 554.8 0.0 1.9e-166 554.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Sulfotransfer_4 PF17784.1 KXH46087.1 - 6.6e-60 202.6 0.0 1.2e-59 201.8 0.0 1.4 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KXH46087.1 - 0.089 13.2 0.0 0.3 11.5 0.0 1.8 1 0 0 1 1 1 0 Sulfotransferase family COesterase PF00135.28 KXH46088.1 - 4e-79 266.8 2.2 3.5e-78 263.7 2.2 1.9 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXH46088.1 - 7.3e-06 26.0 0.1 2.3e-05 24.4 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KXH46088.1 - 0.0083 15.6 0.1 0.0083 15.6 0.1 1.9 2 1 0 2 2 2 1 Prolyl oligopeptidase family AIRS PF00586.24 KXH46088.1 - 0.055 14.1 0.0 0.19 12.4 0.0 1.9 2 0 0 2 2 2 0 AIR synthase related protein, N-terminal domain Peptidase_M35 PF02102.15 KXH46089.1 - 1.2e-82 277.7 18.8 1.4e-82 277.5 18.8 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.6 KXH46089.1 - 8e-43 146.5 7.2 8e-43 146.5 7.2 1.6 1 1 0 1 1 1 1 Lysine-specific metallo-endopeptidase Glyco_hydro_61 PF03443.14 KXH46090.1 - 1.1e-66 224.7 0.2 1.3e-66 224.5 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 NPCBM_assoc PF10633.9 KXH46090.1 - 0.0024 18.1 0.1 2.9 8.2 0.0 2.7 2 0 0 2 2 2 2 NPCBM-associated, NEW3 domain of alpha-galactosidase CSD PF00313.22 KXH46090.1 - 0.18 11.7 0.0 0.35 10.8 0.0 1.4 1 0 0 1 1 1 0 'Cold-shock' DNA-binding domain DUF1614 PF07758.11 KXH46092.1 - 0.1 12.6 0.3 4.3 7.3 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1614) COesterase PF00135.28 KXH46093.1 - 9.7e-78 262.3 0.0 4.4e-73 246.9 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 KXH46093.1 - 3.1e-14 53.3 0.2 5.1e-14 52.6 0.2 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase_phd PF10503.9 KXH46093.1 - 0.009 15.5 0.1 0.017 14.6 0.1 1.4 1 0 0 1 1 1 1 Esterase PHB depolymerase Bac_rhamnosid_N PF08531.10 KXH46093.1 - 0.14 11.9 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 Alpha-L-rhamnosidase N-terminal domain ADH_N PF08240.12 KXH46094.1 - 1.8e-15 56.7 0.3 8.6e-15 54.6 0.3 2.1 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXH46094.1 - 2.2e-08 34.1 0.0 1e-07 32.0 0.0 2.0 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KXH46094.1 - 4.7e-05 23.0 0.1 9.2e-05 22.0 0.1 1.4 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 KXH46094.1 - 0.00082 18.7 0.0 0.0013 18.1 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 KXH46094.1 - 0.036 12.8 0.0 0.047 12.4 0.0 1.1 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.6 KXH46094.1 - 0.079 12.2 0.1 0.23 10.7 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXH46094.1 - 0.086 11.9 0.2 0.086 11.9 0.2 1.6 2 0 0 2 2 2 0 FAD binding domain FAD_binding_3 PF01494.19 KXH46094.1 - 0.099 11.9 0.2 0.14 11.3 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain COesterase PF00135.28 KXH46096.1 - 7.2e-85 285.8 0.0 2.9e-75 254.1 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 KXH46096.1 - 2e-13 50.7 0.0 3.1e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2470 PF10615.9 KXH46097.1 - 2.7e-19 69.6 0.0 3.7e-19 69.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) ApbA_C PF08546.11 KXH46098.1 - 4.5e-25 88.3 0.2 6.9e-25 87.7 0.2 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 KXH46098.1 - 8.6e-24 83.9 0.0 1.3e-23 83.3 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ThiF PF00899.21 KXH46098.1 - 0.0015 17.9 0.6 0.0036 16.7 0.6 1.6 1 0 0 1 1 1 1 ThiF family Tail_VII PF17091.5 KXH46099.1 - 1.2 9.0 5.4 0.71 9.8 0.8 2.4 2 0 0 2 2 2 0 Inovirus G7P protein Phosphoesterase PF04185.14 KXH46100.1 - 2.1e-22 79.8 0.7 4.9e-21 75.3 0.7 2.2 1 1 0 1 1 1 1 Phosphoesterase family Fungal_trans PF04082.18 KXH46101.1 - 5.8e-12 45.2 1.3 1.5e-11 43.9 0.7 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH46101.1 - 7.8e-08 32.3 8.2 1.7e-07 31.2 8.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NPP1 PF05630.11 KXH46102.1 - 3.8e-66 223.0 0.0 4.3e-66 222.8 0.0 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) zf-Di19 PF05605.12 KXH46104.1 - 7.2e-05 23.0 7.0 0.38 11.1 0.1 3.4 3 0 0 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.7 KXH46104.1 - 0.0014 18.9 2.2 0.83 10.0 0.0 3.2 1 1 2 3 3 3 1 C2H2 type zinc-finger (2 copies) CSN7a_helixI PF18392.1 KXH46104.1 - 0.0096 15.8 0.1 0.028 14.3 0.1 1.8 1 0 0 1 1 1 1 COP9 signalosome complex subunit 7a helix I domain zf-C2H2_4 PF13894.6 KXH46104.1 - 0.013 16.3 10.6 5.1 8.2 0.4 4.5 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2HC5 PF06221.13 KXH46104.1 - 0.081 12.9 0.6 11 6.1 0.1 2.5 2 0 0 2 2 2 0 Putative zinc finger motif, C2HC5-type BIR PF00653.21 KXH46104.1 - 0.091 13.4 0.5 1.1 9.9 0.3 2.3 2 0 0 2 2 2 0 Inhibitor of Apoptosis domain zf-nanos PF05741.13 KXH46104.1 - 0.26 11.6 8.1 16 5.8 0.0 3.9 2 1 0 3 3 3 0 Nanos RNA binding domain zf-H2C2_2 PF13465.6 KXH46104.1 - 0.52 10.8 9.0 6.4 7.4 0.1 4.2 5 0 0 5 5 5 0 Zinc-finger double domain CpXC PF14353.6 KXH46104.1 - 1.9 8.5 7.1 3.6 7.6 0.0 3.2 3 1 0 3 3 3 0 CpXC protein DUF1682 PF07946.14 KXH46104.1 - 2.1 7.5 12.9 2.9 7.0 12.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) zf-C2H2_2 PF12756.7 KXH46105.1 - 0.0081 16.5 6.1 0.0093 16.3 0.4 3.1 1 1 2 3 3 3 1 C2H2 type zinc-finger (2 copies) Roughex PF06020.11 KXH46105.1 - 0.071 12.2 4.0 0.11 11.5 4.0 1.2 1 0 0 1 1 1 0 Drosophila roughex protein zf-C2H2_4 PF13894.6 KXH46105.1 - 0.098 13.6 0.3 0.098 13.6 0.3 4.7 5 0 0 5 5 5 0 C2H2-type zinc finger HeLo PF14479.6 KXH46105.1 - 0.13 12.1 6.2 0.075 12.9 0.5 2.5 1 1 0 2 2 2 0 Prion-inhibition and propagation zf-C2H2 PF00096.26 KXH46105.1 - 0.14 12.7 0.2 0.14 12.7 0.2 4.1 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_3rep PF18868.1 KXH46105.1 - 0.28 11.8 3.5 0.63 10.7 1.6 2.5 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats Trypan_PARP PF05887.11 KXH46105.1 - 0.8 9.7 6.5 1.3 9.0 6.5 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) zf-Di19 PF05605.12 KXH46105.1 - 0.81 10.0 7.4 5.2 7.4 0.0 3.2 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding SEN1_N PF12726.7 KXH46114.1 - 3.8e-204 680.1 5.5 5.7e-204 679.6 5.5 1.3 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.6 KXH46114.1 - 1.2e-71 241.5 0.9 1.2e-71 241.5 0.9 2.9 3 0 0 3 3 3 1 AAA domain AAA_12 PF13087.6 KXH46114.1 - 1.7e-61 207.3 0.0 3.2e-61 206.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KXH46114.1 - 1.6e-10 41.5 0.0 8.2e-10 39.2 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KXH46114.1 - 4.4e-09 36.3 0.3 3.3e-05 23.7 0.2 2.7 2 0 0 2 2 2 2 AAA domain UvrD-helicase PF00580.21 KXH46114.1 - 2.2e-06 27.4 4.1 0.00017 21.2 0.0 3.7 2 1 1 3 3 3 1 UvrD/REP helicase N-terminal domain Viral_helicase1 PF01443.18 KXH46114.1 - 9.3e-06 25.5 0.1 0.082 12.6 0.0 3.5 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 KXH46114.1 - 0.081 13.2 0.0 0.54 10.5 0.0 2.5 1 0 0 1 1 1 0 AAA domain VWA_2 PF13519.6 KXH46114.1 - 0.28 11.9 1.1 1.2 9.8 0.4 2.4 2 0 0 2 2 2 0 von Willebrand factor type A domain AnfG_VnfG PF03139.15 KXH46114.1 - 3.1 7.9 4.9 2.7 8.1 0.1 3.0 3 0 0 3 3 3 0 Vanadium/alternative nitrogenase delta subunit HhH-GPD PF00730.25 KXH46115.1 - 6.6e-08 33.0 0.1 2e-07 31.4 0.0 1.8 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein Ribosomal_L1 PF00687.21 KXH46115.1 - 0.12 12.1 2.3 0.36 10.5 0.2 2.5 3 0 0 3 3 3 0 Ribosomal protein L1p/L10e family DNA_methylase PF00145.17 KXH46116.1 - 1.3e-39 136.4 0.0 1.3e-29 103.7 0.0 2.2 1 1 1 2 2 2 2 C-5 cytosine-specific DNA methylase Pectinesterase PF01095.19 KXH46117.1 - 2.2e-28 98.9 0.1 1.2e-23 83.2 0.2 2.1 2 0 0 2 2 2 2 Pectinesterase Glyco_hydro_28 PF00295.17 KXH46118.1 - 1.4e-52 178.7 13.8 2.1e-52 178.2 13.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Acetyltransf_3 PF13302.7 KXH46119.1 - 1.5e-14 54.8 0.0 5.7e-14 53.0 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain POP1 PF06978.11 KXH46120.1 - 2.4e-75 253.1 14.1 3.9e-75 252.3 14.1 1.4 1 0 0 1 1 1 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.12 KXH46120.1 - 3e-27 94.8 1.4 8.9e-27 93.3 0.1 2.4 2 0 0 2 2 2 1 POPLD (NUC188) domain Acetyltransf_1 PF00583.25 KXH46125.1 - 4.7e-05 23.6 0.0 7.9e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family CENP-T_C PF15511.6 KXH46126.1 - 0.00029 20.9 0.1 0.00041 20.4 0.1 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 KXH46126.1 - 0.0014 18.9 0.2 0.0019 18.6 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KXH46126.1 - 0.027 14.8 1.1 0.061 13.6 0.1 2.0 1 1 1 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KXH46126.1 - 0.043 13.9 0.0 0.055 13.6 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit CENP-S PF15630.6 KXH46126.1 - 0.061 13.7 0.1 0.089 13.2 0.1 1.4 1 1 0 1 1 1 0 CENP-S protein PCP_red PF08369.10 KXH46126.1 - 0.083 13.1 0.2 0.83 9.9 0.1 2.2 2 0 0 2 2 2 0 Proto-chlorophyllide reductase 57 kD subunit AbiEi_4 PF13338.6 KXH46126.1 - 0.12 12.5 1.7 2.8 8.2 0.8 2.6 2 1 0 2 2 2 0 Transcriptional regulator, AbiEi antitoxin TFIID_20kDa PF03847.13 KXH46126.1 - 0.18 12.4 0.2 0.31 11.6 0.1 1.5 1 1 0 1 1 1 0 Transcription initiation factor TFIID subunit A Svf1_C PF17187.4 KXH46127.1 - 2.3e-62 209.7 0.0 1.8e-61 206.8 0.0 2.1 2 0 0 2 2 2 1 Svf1-like C-terminal lipocalin-like domain Svf1 PF08622.10 KXH46127.1 - 4.7e-55 186.1 0.1 7e-55 185.5 0.1 1.3 1 0 0 1 1 1 1 Svf1-like N-terminal lipocalin domain LPD18 PF18832.1 KXH46127.1 - 0.13 12.4 0.0 0.4 10.8 0.0 1.8 2 0 0 2 2 2 0 Large polyvalent protein-associated domain 18 Ribosomal_L11 PF00298.19 KXH46128.1 - 4.2e-29 100.9 0.2 7.1e-29 100.1 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.14 KXH46128.1 - 1.4e-25 88.9 0.1 2.3e-25 88.2 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Pkinase PF00069.25 KXH46129.1 - 3.1e-47 161.1 0.0 1.4e-46 159.0 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXH46129.1 - 2.8e-21 76.0 0.0 4.8e-21 75.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXH46129.1 - 0.0052 16.7 0.0 0.01 15.8 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KXH46129.1 - 0.026 13.5 0.0 0.041 12.8 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain SAPS PF04499.15 KXH46129.1 - 0.15 10.8 2.9 0.13 11.1 0.2 1.9 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein Cpn10 PF00166.21 KXH46130.1 - 8.7e-29 99.4 0.0 9.7e-29 99.3 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit 5-FTHF_cyc-lig PF01812.20 KXH46130.1 - 0.088 12.6 0.0 0.1 12.5 0.0 1.1 1 0 0 1 1 1 0 5-formyltetrahydrofolate cyclo-ligase family Glyco_hydro_61 PF03443.14 KXH46131.1 - 4.1e-53 180.4 0.0 8.6e-53 179.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 SNF2_N PF00176.23 KXH46134.1 - 5.5e-70 235.8 0.1 7.5e-70 235.4 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KXH46134.1 - 7.3e-15 55.3 0.0 4.8e-14 52.6 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.6 KXH46134.1 - 1.1e-10 41.2 9.8 2.4e-10 40.1 9.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KXH46134.1 - 2.4e-09 36.9 7.9 2.4e-09 36.9 7.9 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) HIRAN PF08797.11 KXH46134.1 - 2.8e-09 36.8 0.0 1e-08 35.0 0.0 1.9 1 1 0 1 1 1 1 HIRAN domain zf-C3HC4 PF00097.25 KXH46134.1 - 1.1e-08 34.8 9.4 1.1e-08 34.8 9.4 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXH46134.1 - 1.8e-08 34.6 11.3 1.8e-08 34.5 8.7 2.1 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 KXH46134.1 - 9.3e-07 28.7 9.0 2e-06 27.6 9.0 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KXH46134.1 - 9.7e-07 28.7 7.7 9.7e-07 28.7 7.7 2.0 2 0 0 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KXH46134.1 - 2.1e-06 27.5 7.4 2.1e-06 27.5 7.4 1.8 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KXH46134.1 - 4e-06 26.9 8.6 9.5e-06 25.7 8.6 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 KXH46134.1 - 1.3e-05 25.4 5.1 3.2e-05 24.1 5.1 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KXH46134.1 - 0.00094 19.2 2.6 0.0024 17.9 2.6 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.6 KXH46134.1 - 0.0014 18.4 4.6 0.0037 17.1 4.6 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_10 PF16685.5 KXH46134.1 - 0.0018 18.4 6.7 0.0049 17.0 6.7 1.7 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-RING_4 PF14570.6 KXH46134.1 - 0.0059 16.4 5.5 0.013 15.2 5.5 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-Nse PF11789.8 KXH46134.1 - 0.049 13.5 6.4 0.23 11.3 5.5 2.3 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit Vps39_2 PF10367.9 KXH46134.1 - 0.46 11.0 2.7 5.7 7.4 0.6 2.8 1 1 1 2 2 2 0 Vacuolar sorting protein 39 domain 2 zf-RING_11 PF17123.5 KXH46134.1 - 0.64 9.8 5.5 1.9 8.3 5.5 1.9 1 0 0 1 1 1 0 RING-like zinc finger CDO_I PF05995.12 KXH46135.1 - 4.6e-43 146.5 0.0 5.9e-43 146.1 0.0 1.1 1 0 0 1 1 1 1 Cysteine dioxygenase type I PCO_ADO PF07847.12 KXH46135.1 - 0.051 13.0 0.3 0.071 12.5 0.0 1.6 2 0 0 2 2 2 0 PCO_ADO SLAC1 PF03595.17 KXH46136.1 - 8e-83 278.4 47.5 9.6e-83 278.1 47.5 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Wyosine_form PF08608.12 KXH46137.1 - 1.2e-24 86.5 0.0 2.7e-24 85.3 0.0 1.7 1 0 0 1 1 1 1 Wyosine base formation Radical_SAM PF04055.21 KXH46137.1 - 4.2e-22 79.3 0.0 1.2e-21 77.8 0.0 1.8 1 1 0 1 1 1 1 Radical SAM superfamily Flavodoxin_1 PF00258.25 KXH46137.1 - 1.9e-12 47.6 0.1 1.6e-11 44.6 0.1 2.6 2 1 0 2 2 2 1 Flavodoxin MAS20 PF02064.15 KXH46138.1 - 7.4e-42 142.5 2.0 9e-42 142.2 2.0 1.0 1 0 0 1 1 1 1 MAS20 protein import receptor RRP36 PF06102.12 KXH46138.1 - 0.0023 17.9 3.2 0.0028 17.7 3.2 1.1 1 0 0 1 1 1 1 rRNA biogenesis protein RRP36 AP-5_subunit_s1 PF15001.6 KXH46138.1 - 0.0056 16.7 2.9 0.0067 16.4 2.9 1.1 1 0 0 1 1 1 1 AP-5 complex subunit sigma-1 CSRNP_N PF16019.5 KXH46138.1 - 0.0067 16.4 1.6 0.0087 16.0 1.6 1.1 1 0 0 1 1 1 1 Cysteine/serine-rich nuclear protein N-terminus Ctr PF04145.15 KXH46138.1 - 0.14 12.8 0.0 0.15 12.7 0.0 1.1 1 0 0 1 1 1 0 Ctr copper transporter family Rhabdo_ncap PF00945.18 KXH46138.1 - 0.2 10.5 0.7 0.23 10.3 0.7 1.1 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein Exo84_C PF16528.5 KXH46139.1 - 6.7e-75 251.4 0.0 6.7e-75 251.4 0.0 2.5 3 1 1 4 4 4 1 Exocyst component 84 C-terminal Vps51 PF08700.11 KXH46139.1 - 1.3e-14 54.0 1.0 1.3e-14 54.0 1.0 2.1 3 0 0 3 3 3 1 Vps51/Vps67 COG2 PF06148.11 KXH46139.1 - 0.25 11.4 6.7 0.038 14.1 0.9 2.3 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF615 PF04751.14 KXH46139.1 - 2.5 8.1 8.7 0.17 11.8 1.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF615) DUF4407 PF14362.6 KXH46139.1 - 6.7 6.0 10.2 1e+02 2.1 10.2 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) APG6_N PF17675.1 KXH46139.1 - 9.8 6.7 13.4 6.2 7.4 2.3 2.5 2 0 0 2 2 2 0 Apg6 coiled-coil region Metallophos PF00149.28 KXH46140.1 - 3.6e-38 132.1 0.5 5.8e-38 131.4 0.5 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KXH46140.1 - 0.048 14.1 0.1 0.099 13.1 0.1 1.5 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain DUF3112 PF11309.8 KXH46141.1 - 1.3e-14 54.2 8.7 7.5e-10 38.6 1.2 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3112) GSHPx PF00255.19 KXH46191.1 - 2e-41 139.9 0.1 2.5e-41 139.6 0.1 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 KXH46191.1 - 0.00024 21.0 0.0 0.00038 20.4 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KXH46191.1 - 0.00047 19.9 0.0 0.00068 19.4 0.0 1.2 1 0 0 1 1 1 1 Redoxin DAO PF01266.24 KXH46192.1 - 7.6e-63 213.2 3.2 1.1e-62 212.6 3.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXH46192.1 - 0.003 17.7 0.6 0.008 16.4 0.6 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KXH46192.1 - 0.014 15.9 0.1 1.1 9.9 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXH46192.1 - 0.026 13.7 0.0 1.9 7.7 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.19 KXH46192.1 - 0.088 12.2 0.1 0.65 9.3 0.0 2.0 2 0 0 2 2 2 0 GMC oxidoreductase DHDPS PF00701.22 KXH46193.1 - 4.1e-32 111.1 0.0 5e-32 110.8 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family GFO_IDH_MocA PF01408.22 KXH46194.1 - 5e-11 43.5 0.5 2.2e-10 41.4 0.5 2.1 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 KXH46194.1 - 0.065 13.9 0.1 0.13 13.0 0.1 1.6 1 1 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain CoA_binding_2 PF13380.6 KXH46194.1 - 0.14 12.7 0.0 0.27 11.7 0.0 1.4 1 0 0 1 1 1 0 CoA binding domain Nop16 PF09420.10 KXH46195.1 - 5.9e-72 242.1 10.4 6.6e-72 241.9 10.4 1.0 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 MARVEL PF01284.23 KXH46196.1 - 9.2e-06 25.8 9.9 1.6e-05 25.0 9.9 1.3 1 0 0 1 1 1 1 Membrane-associating domain DUF4281 PF14108.6 KXH46196.1 - 0.0001 22.7 2.4 0.00011 22.6 1.1 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4281) Rit1_C PF17184.4 KXH46197.1 - 7.4e-111 369.9 0.0 9.2e-111 369.6 0.0 1.1 1 0 0 1 1 1 1 Rit1 N-terminal domain Init_tRNA_PT PF04179.12 KXH46197.1 - 1.5e-33 115.4 0.0 3.2e-33 114.3 0.0 1.6 1 0 0 1 1 1 1 Rit1 DUSP-like domain HAD_2 PF13419.6 KXH46198.1 - 1.1e-23 84.3 0.0 1.3e-23 84.0 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KXH46198.1 - 1.1e-11 45.4 0.1 6.5e-11 42.9 0.1 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KXH46198.1 - 8.1e-06 25.8 0.0 1.6e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like NIF PF03031.18 KXH46198.1 - 0.0021 17.8 0.0 0.039 13.7 0.0 2.2 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase HAD PF12710.7 KXH46198.1 - 0.02 15.3 0.0 0.031 14.7 0.0 1.4 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 KXH46198.1 - 0.026 14.6 0.0 1.2 9.3 0.0 2.3 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase SPAR_C PF11881.8 KXH46198.1 - 0.076 12.9 0.0 0.098 12.6 0.0 1.1 1 0 0 1 1 1 0 C-terminal domain of SPAR protein DnaG_DnaB_bind PF08278.11 KXH46198.1 - 0.13 12.8 0.0 0.19 12.3 0.0 1.3 1 0 0 1 1 1 0 DNA primase DnaG DnaB-binding DnaJ_C PF01556.18 KXH46199.1 - 7.5e-38 129.9 0.6 1e-37 129.5 0.6 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KXH46199.1 - 3.9e-27 94.1 1.7 6.5e-27 93.5 1.7 1.4 1 0 0 1 1 1 1 DnaJ domain TGF_beta_GS PF08515.12 KXH46200.1 - 0.07 12.6 3.1 7.4 6.2 0.7 2.7 2 0 0 2 2 2 0 Transforming growth factor beta type I GS-motif Snapin_Pallidin PF14712.6 KXH46200.1 - 0.27 11.7 1.4 0.54 10.7 0.3 2.0 2 0 0 2 2 2 0 Snapin/Pallidin UQ_con PF00179.26 KXH46201.1 - 8.6e-35 119.4 0.0 1.2e-34 118.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KXH46201.1 - 0.12 12.7 0.0 0.18 12.1 0.0 1.5 1 0 0 1 1 1 0 RWD domain HGTP_anticodon2 PF12745.7 KXH46202.1 - 1e-87 294.0 1.0 1e-87 294.0 1.0 2.7 3 0 0 3 3 3 1 Anticodon binding domain of tRNAs Pkinase PF00069.25 KXH46202.1 - 6.8e-75 251.8 0.0 4.9e-35 121.2 0.0 3.7 3 1 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 KXH46202.1 - 2.2e-48 164.8 0.0 3.7e-20 72.3 0.0 3.3 3 0 0 3 3 3 3 Protein tyrosine kinase tRNA-synt_His PF13393.6 KXH46202.1 - 4.1e-17 62.4 0.0 1.1e-16 61.1 0.0 1.8 1 0 0 1 1 1 1 Histidyl-tRNA synthetase RWD PF05773.22 KXH46202.1 - 2.1e-10 40.9 0.0 5.7e-10 39.5 0.0 1.8 1 0 0 1 1 1 1 RWD domain APH PF01636.23 KXH46202.1 - 4e-07 30.2 3.9 0.0062 16.5 0.2 3.2 3 0 0 3 3 3 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXH46202.1 - 6.5e-07 28.5 0.7 0.0089 14.8 0.1 3.2 3 0 0 3 3 3 2 Fungal protein kinase Kinase-like PF14531.6 KXH46202.1 - 2.2e-05 23.9 0.0 0.00051 19.4 0.0 2.6 2 0 0 2 2 2 1 Kinase-like HGTP_anticodon PF03129.20 KXH46202.1 - 0.006 16.7 0.0 0.024 14.8 0.0 2.1 1 0 0 1 1 1 1 Anticodon binding domain YrbL-PhoP_reg PF10707.9 KXH46202.1 - 0.038 13.5 0.0 1.3 8.5 0.0 2.4 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Med21 PF11221.8 KXH46202.1 - 0.26 11.5 6.7 0.034 14.4 1.8 2.1 2 0 0 2 2 1 0 Subunit 21 of Mediator complex CDC45 PF02724.14 KXH46202.1 - 1.4 7.1 11.3 0.98 7.6 3.7 2.3 2 0 0 2 2 2 0 CDC45-like protein PPP4R2 PF09184.11 KXH46202.1 - 6.5 6.3 15.8 1.1 8.8 7.0 2.4 2 0 0 2 2 2 0 PPP4R2 Cut12 PF11500.8 KXH46203.1 - 1.6e-47 161.1 21.1 1.6e-47 161.1 21.1 4.4 2 1 1 3 3 3 1 Spindle pole body formation-associated protein TSC22 PF01166.18 KXH46203.1 - 0.46 10.8 12.9 1.3 9.4 2.0 3.7 2 1 1 3 3 3 0 TSC-22/dip/bun family FlaC_arch PF05377.11 KXH46203.1 - 6.8 7.2 12.0 0.67 10.4 0.9 3.8 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) IGPD PF00475.18 KXH46204.1 - 3.7e-60 202.4 0.3 5.2e-60 201.9 0.3 1.2 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase DER1 PF04511.15 KXH46205.1 - 1.4e-25 90.4 7.4 1.6e-25 90.1 7.4 1.0 1 0 0 1 1 1 1 Der1-like family DUF5090 PF17009.5 KXH46205.1 - 1.1 9.2 2.7 2 8.3 2.7 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF5090) EphA2_TM PF14575.6 KXH46206.1 - 0.17 12.8 0.0 0.81 10.6 0.0 2.2 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF3481 PF11980.8 KXH46206.1 - 0.4 10.4 3.0 1 9.1 0.3 2.6 2 0 0 2 2 2 0 C-terminal domain of neuropilin glycoprotein CN_hydrolase PF00795.22 KXH46208.1 - 1.3e-14 54.2 0.0 2.3e-13 50.1 0.0 2.1 2 0 0 2 2 2 2 Carbon-nitrogen hydrolase DKCLD PF08068.12 KXH46210.1 - 5.2e-30 103.3 0.1 8.8e-29 99.4 0.1 2.4 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_C_2 PF16198.5 KXH46210.1 - 2.2e-22 79.0 0.6 4.4e-22 78.0 0.6 1.6 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain PUA PF01472.20 KXH46210.1 - 3.4e-22 78.2 1.1 6.5e-22 77.3 1.1 1.5 1 0 0 1 1 1 1 PUA domain TruB_N PF01509.18 KXH46210.1 - 1.4e-21 77.4 0.1 1.2e-18 67.9 0.1 3.3 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) UPF0113 PF03657.13 KXH46210.1 - 0.00073 19.8 0.0 0.0016 18.7 0.0 1.5 1 0 0 1 1 1 1 UPF0113 PUA domain Med19 PF10278.9 KXH46210.1 - 0.54 10.2 8.8 1.1 9.1 8.8 1.5 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Glyco_hydro_43 PF04616.14 KXH46211.1 - 8e-23 81.2 0.0 1e-22 80.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 SUIM_assoc PF16619.5 KXH46212.1 - 0.0092 16.0 1.0 0.041 14.0 1.0 2.1 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 CD34_antigen PF06365.12 KXH46212.1 - 0.14 11.8 0.2 0.28 10.7 0.2 1.6 1 1 0 1 1 1 0 CD34/Podocalyxin family EphA2_TM PF14575.6 KXH46212.1 - 0.24 12.3 0.7 0.69 10.8 0.7 2.0 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain SAC3_GANP PF03399.16 KXH46213.1 - 7.7e-92 307.8 0.0 1.1e-91 307.2 0.0 1.3 1 0 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 KXH46213.1 - 0.0052 16.8 0.0 0.011 15.8 0.0 1.4 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family Peptidase_C58 PF03543.14 KXH46213.1 - 0.31 10.7 2.8 0.48 10.1 0.9 2.3 2 0 0 2 2 2 0 Yersinia/Haemophilus virulence surface antigen LTV PF04180.14 KXH46214.1 - 2.5e-131 439.0 10.2 2.8e-131 438.8 10.2 1.0 1 0 0 1 1 1 1 Low temperature viability protein SDA1 PF05285.12 KXH46215.1 - 0.0023 17.4 13.4 0.0039 16.7 13.4 1.4 1 0 0 1 1 1 1 SDA1 eIF-3c_N PF05470.12 KXH46215.1 - 0.015 13.7 6.1 0.02 13.2 6.1 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus MCLC PF05934.11 KXH46215.1 - 0.15 10.7 1.8 0.22 10.2 1.8 1.1 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) SAPS PF04499.15 KXH46215.1 - 0.25 10.1 5.5 0.39 9.5 5.5 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF4366 PF14283.6 KXH46215.1 - 3.4 7.7 7.3 7.2 6.6 7.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Presenilin PF01080.17 KXH46215.1 - 5.4 5.7 5.6 8.6 5.0 5.6 1.2 1 0 0 1 1 1 0 Presenilin PBD PF00786.28 KXH46216.1 - 0.0032 17.8 0.6 0.038 14.3 0.2 2.5 2 0 0 2 2 2 1 P21-Rho-binding domain HLH PF00010.26 KXH46217.1 - 5.6e-12 45.4 0.0 1e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain MerR-DNA-bind PF09278.11 KXH46217.1 - 0.95 10.0 4.5 3 8.5 4.5 1.8 1 0 0 1 1 1 0 MerR, DNA binding MFAP1 PF06991.11 KXH46217.1 - 6.5 6.5 13.0 0.068 13.0 5.1 1.6 2 0 0 2 2 2 0 Microfibril-associated/Pre-mRNA processing FAM70 PF14967.6 KXH46217.1 - 7.7 5.9 5.2 1.2 8.6 0.5 1.9 2 1 0 2 2 2 0 FAM70 protein AMP-binding PF00501.28 KXH46218.1 - 3.2e-61 207.2 0.0 4.2e-61 206.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXH46218.1 - 6.5e-20 71.9 0.1 1.4e-19 70.8 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Ins134_P3_kin_N PF17927.1 KXH46218.1 - 0.076 13.4 0.1 0.18 12.2 0.1 1.6 1 0 0 1 1 1 0 Inositol 1,3,4-trisphosphate 5/6-kinase pre-ATP-grasp domain LysR_substrate PF03466.20 KXH46218.1 - 0.13 11.6 0.0 0.3 10.4 0.0 1.6 2 0 0 2 2 2 0 LysR substrate binding domain POB3_N PF17292.2 KXH46219.1 - 1.4e-30 105.5 0.3 2.5e-29 101.5 0.1 2.6 3 0 0 3 3 3 1 POB3-like N-terminal PH domain SSrecog PF03531.14 KXH46219.1 - 1.7e-30 104.7 0.1 9.6e-30 102.3 0.0 2.4 2 0 0 2 2 2 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.12 KXH46219.1 - 1.6e-22 79.7 0.1 1.6e-21 76.5 0.0 2.5 3 0 0 3 3 3 1 Histone chaperone Rttp106-like PPP4R2 PF09184.11 KXH46219.1 - 5.8 6.4 14.8 9.1 5.8 14.8 1.2 1 0 0 1 1 1 0 PPP4R2 Aldo_ket_red PF00248.21 KXH46220.1 - 5.8e-37 127.5 0.0 7e-37 127.2 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family zinc_ribbon_2 PF13240.6 KXH46221.1 - 0.06 13.1 0.4 0.12 12.1 0.4 1.5 1 0 0 1 1 1 0 zinc-ribbon domain Glyco_hydro_1 PF00232.18 KXH46223.1 - 1.3e-141 472.1 0.0 1.8e-141 471.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Mannosyl_trans3 PF11051.8 KXH46224.1 - 0.021 14.2 0.0 0.035 13.4 0.0 1.3 1 0 0 1 1 1 0 Mannosyltransferase putative NfrA_C PF13283.6 KXH46224.1 - 0.074 12.5 0.3 0.13 11.7 0.0 1.5 2 0 0 2 2 2 0 Bacteriophage N adsorption protein A C-term SBF_like PF13593.6 KXH46226.1 - 4.9e-89 298.7 18.5 5.7e-89 298.5 18.5 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) DUF4203 PF13886.6 KXH46227.1 - 3.9e-48 163.8 29.7 4.9e-48 163.5 29.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) Autoind_bind PF03472.15 KXH46227.1 - 0.13 11.7 1.0 0.3 10.5 1.0 1.5 1 0 0 1 1 1 0 Autoinducer binding domain DUF4381 PF14316.6 KXH46227.1 - 0.2 11.9 0.0 0.2 11.9 0.0 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF4381) Erf4 PF10256.9 KXH46230.1 - 5.1e-40 136.2 0.0 8.5e-40 135.5 0.0 1.4 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family SSB PF00436.25 KXH46231.1 - 8.6e-19 67.5 0.0 1.1e-18 67.2 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family GSH_synth_ATP PF03917.17 KXH46232.1 - 7.8e-135 449.4 0.0 9e-135 449.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 KXH46232.1 - 6.5e-33 113.3 0.0 1.1e-32 112.5 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic glutathione synthase SNF2_N PF00176.23 KXH46233.1 - 4.1e-44 150.7 0.0 7.6e-44 149.9 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KXH46233.1 - 1.7e-20 73.4 0.0 5.3e-20 71.8 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXH46233.1 - 1e-06 28.9 0.0 3.4e-06 27.2 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Aminotran_1_2 PF00155.21 KXH46234.1 - 3.5e-81 273.2 0.0 4.6e-81 272.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KXH46234.1 - 3.1e-05 22.7 0.0 4.9e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 KXH46234.1 - 0.00046 19.2 0.0 0.0009 18.3 0.0 1.5 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KXH46234.1 - 0.016 14.5 0.3 0.029 13.7 0.3 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family PTS_EIIA_2 PF00359.22 KXH46234.1 - 0.034 14.1 0.0 0.069 13.1 0.0 1.5 1 0 0 1 1 1 0 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 Fungal_trans PF04082.18 KXH46235.1 - 0.00098 18.2 0.2 0.0018 17.3 0.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain DENN PF02141.21 KXH46235.1 - 0.046 13.7 0.2 0.088 12.7 0.2 1.4 1 0 0 1 1 1 0 DENN (AEX-3) domain Trp_syntA PF00290.20 KXH46235.1 - 0.052 12.4 0.2 0.086 11.7 0.2 1.2 1 0 0 1 1 1 0 Tryptophan synthase alpha chain Zn_clus PF00172.18 KXH46235.1 - 0.076 13.2 11.0 0.14 12.3 11.0 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain HK PF02110.15 KXH46236.1 - 6.1e-74 248.5 0.9 9.3e-74 247.9 0.2 1.6 2 0 0 2 2 2 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.17 KXH46236.1 - 3.3e-57 192.7 0.7 5.1e-57 192.1 0.7 1.3 1 0 0 1 1 1 1 Thiamine monophosphate synthase Peripla_BP_6 PF13458.6 KXH46236.1 - 0.013 15.2 2.1 0.55 9.8 0.1 3.3 1 1 0 3 3 3 0 Periplasmic binding protein Carb_kinase PF01256.17 KXH46236.1 - 0.027 14.0 0.2 0.058 12.9 0.2 1.5 1 0 0 1 1 1 0 Carbohydrate kinase Isochorismatase PF00857.20 KXH46237.1 - 4.6e-31 108.3 0.1 5.7e-31 108.0 0.1 1.1 1 0 0 1 1 1 1 Isochorismatase family Lipase_GDSL_2 PF13472.6 KXH46239.1 - 9.6e-22 78.2 0.0 1.5e-21 77.6 0.0 1.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KXH46239.1 - 6.6e-12 45.8 0.0 9.4e-12 45.3 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase ABM PF03992.16 KXH46239.1 - 0.12 12.5 0.0 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 Antibiotic biosynthesis monooxygenase Lipase_GDSL_3 PF14606.6 KXH46239.1 - 0.24 11.5 0.0 0.4 10.8 0.0 1.3 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family BP28CT PF08146.12 KXH46240.1 - 4e-42 143.7 1.9 7e-42 143.0 0.3 2.4 2 0 0 2 2 2 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.8 KXH46240.1 - 8.7e-27 93.8 0.0 8.7e-27 93.8 0.0 4.9 5 0 0 5 5 5 1 U3 small nucleolar RNA-associated protein 10 HEAT PF02985.22 KXH46240.1 - 4.5e-07 29.6 10.2 0.037 14.3 0.0 6.5 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.6 KXH46240.1 - 0.0023 18.3 16.3 0.29 11.6 0.0 6.3 7 0 0 7 7 7 2 HEAT repeats Pyr_redox_2 PF07992.14 KXH46241.1 - 6.7e-45 153.6 0.0 1.7e-39 135.8 0.0 2.1 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXH46241.1 - 7.8e-14 52.0 0.0 8e-11 42.3 0.0 3.4 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXH46241.1 - 1.3e-05 24.6 0.0 0.016 14.5 0.0 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXH46241.1 - 0.0014 17.8 0.2 0.64 9.0 0.1 3.1 3 1 1 4 4 4 2 FAD binding domain K_oxygenase PF13434.6 KXH46241.1 - 0.0036 16.5 0.1 7.3 5.6 0.0 3.7 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KXH46241.1 - 0.029 14.6 0.0 8.7 6.7 0.0 2.7 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain P5CR_dimer PF14748.6 KXH46242.1 - 1.8e-35 121.3 1.9 4.2e-35 120.1 1.9 1.6 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 KXH46242.1 - 4.3e-12 46.5 0.7 1.6e-10 41.4 0.0 2.5 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent CTK3 PF12243.8 KXH46243.1 - 1.5e-50 170.4 0.5 2e-50 169.9 0.5 1.2 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.8 KXH46243.1 - 8.7e-22 77.1 4.9 8.7e-22 77.1 4.9 2.0 2 0 0 2 2 2 1 CTD kinase subunit gamma CTK3 C-terminus Rcd1 PF04078.13 KXH46243.1 - 0.012 14.9 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 Cell differentiation family, Rcd1-like Ribosomal_L12 PF00542.19 KXH46244.1 - 2.4e-19 69.5 4.9 2.4e-19 69.5 4.9 2.6 3 0 0 3 3 3 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 KXH46244.1 - 6.1e-12 45.0 11.9 6.1e-12 45.0 11.9 3.2 3 1 0 3 3 3 1 Ribosomal protein L7/L12 dimerisation domain Ribosomal_60s PF00428.19 KXH46244.1 - 2.2 8.9 15.0 0.13 12.8 8.7 2.1 2 1 0 2 2 2 0 60s Acidic ribosomal protein AAA_5 PF07728.14 KXH46245.1 - 7.2e-121 398.6 0.0 6.4e-21 74.8 0.0 9.5 9 0 0 9 9 9 9 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 KXH46245.1 - 1.2e-53 179.8 0.5 9.6e-21 74.0 0.0 5.5 5 0 0 5 5 4 3 Midasin AAA lid domain AAA_lid_5 PF17865.1 KXH46245.1 - 7.8e-32 109.5 0.3 1.6e-30 105.3 0.0 3.0 2 0 0 2 2 2 1 Midasin AAA lid domain AAA PF00004.29 KXH46245.1 - 1.1e-28 100.2 0.0 0.00038 20.9 0.0 7.0 6 0 0 6 6 6 5 ATPase family associated with various cellular activities (AAA) AAA_3 PF07726.11 KXH46245.1 - 9.3e-28 96.7 0.0 1.8e-09 37.6 0.0 7.0 7 0 0 7 7 6 3 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 KXH46245.1 - 1.7e-26 92.8 2.8 0.00015 21.3 0.0 6.9 6 1 0 6 6 6 5 P-loop containing dynein motor region AAA_16 PF13191.6 KXH46245.1 - 1.3e-25 90.8 17.8 0.00062 20.2 0.0 9.0 6 2 0 6 6 6 6 AAA ATPase domain Dynein_heavy PF03028.15 KXH46245.1 - 1.3e-23 83.3 0.0 0.0021 18.1 0.0 8.2 7 1 0 7 7 7 4 Dynein heavy chain region D6 P-loop domain AAA_22 PF13401.6 KXH46245.1 - 5.4e-21 75.3 2.9 0.006 16.9 0.0 8.0 7 0 0 7 7 7 4 AAA domain AAA_6 PF12774.7 KXH46245.1 - 1.5e-18 66.9 0.0 0.011 14.7 0.0 8.3 8 0 0 8 8 8 4 Hydrolytic ATP binding site of dynein motor region AAA_18 PF13238.6 KXH46245.1 - 1.8e-17 64.1 0.3 0.04 14.5 0.0 7.2 6 0 0 6 6 6 3 AAA domain AAA_33 PF13671.6 KXH46245.1 - 1.8e-17 63.8 0.1 0.013 15.7 0.0 7.3 7 1 0 7 7 6 4 AAA domain Sigma54_activat PF00158.26 KXH46245.1 - 1.7e-16 60.3 0.0 0.13 12.0 0.1 6.7 6 0 0 6 6 6 4 Sigma-54 interaction domain AAA_14 PF13173.6 KXH46245.1 - 3.1e-15 56.4 0.0 0.019 15.0 0.0 7.7 7 0 0 7 7 7 3 AAA domain TsaE PF02367.17 KXH46245.1 - 4.1e-15 55.9 4.0 0.006 16.6 0.2 6.4 6 0 0 6 6 6 4 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 KXH46245.1 - 9.3e-14 51.6 0.7 0.1 12.3 0.0 7.9 7 1 0 7 7 6 2 AAA domain ABC_tran PF00005.27 KXH46245.1 - 1.4e-13 51.5 3.1 0.12 12.9 0.1 7.5 6 1 0 6 6 6 2 ABC transporter RNA_helicase PF00910.22 KXH46245.1 - 2.5e-13 50.4 0.7 0.67 10.4 0.0 6.8 6 0 0 6 6 6 2 RNA helicase NACHT PF05729.12 KXH46245.1 - 4.1e-13 49.6 5.0 0.081 12.8 0.1 6.1 5 0 0 5 5 5 4 NACHT domain T2SSE PF00437.20 KXH46245.1 - 1e-12 47.7 4.0 0.015 14.4 0.0 6.5 6 0 0 6 6 6 1 Type II/IV secretion system protein RuvB_N PF05496.12 KXH46245.1 - 9.6e-12 44.9 4.2 0.029 14.1 0.0 6.3 5 1 1 6 6 6 3 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 KXH46245.1 - 5e-11 42.5 2.5 1 8.9 0.0 5.7 5 0 0 5 5 5 2 AAA domain AAA_29 PF13555.6 KXH46245.1 - 1.3e-10 40.8 0.5 0.22 11.3 0.0 6.6 6 0 0 6 6 6 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KXH46245.1 - 2.1e-10 40.7 1.5 0.8 9.6 0.1 6.6 6 0 0 6 6 6 1 RsgA GTPase AAA_28 PF13521.6 KXH46245.1 - 4.1e-10 40.1 5.0 0.65 10.2 0.0 7.7 8 0 0 8 8 6 1 AAA domain Mg_chelatase PF01078.21 KXH46245.1 - 5.7e-10 38.9 4.4 11 5.4 0.0 9.0 9 0 0 9 9 9 0 Magnesium chelatase, subunit ChlI Rad17 PF03215.15 KXH46245.1 - 6.9e-10 39.1 1.5 0.17 11.8 0.0 6.3 6 0 0 6 6 6 2 Rad17 P-loop domain Sigma54_activ_2 PF14532.6 KXH46245.1 - 1.1e-09 38.6 0.3 0.028 14.6 0.0 6.4 6 0 0 6 6 6 2 Sigma-54 interaction domain Zeta_toxin PF06414.12 KXH46245.1 - 2.7e-09 36.6 5.6 0.11 11.8 0.0 7.3 7 0 0 7 7 7 1 Zeta toxin IstB_IS21 PF01695.17 KXH46245.1 - 7.8e-09 35.5 0.4 0.81 9.4 0.0 6.4 6 0 0 6 6 6 1 IstB-like ATP binding protein NTPase_1 PF03266.15 KXH46245.1 - 1.1e-07 32.0 5.7 1.3 8.9 0.0 6.6 6 0 0 6 6 6 2 NTPase SRP54 PF00448.22 KXH46245.1 - 2.2e-07 30.7 1.7 0.66 9.6 0.1 5.0 5 0 0 5 5 5 1 SRP54-type protein, GTPase domain ATPase_2 PF01637.18 KXH46245.1 - 4.9e-07 29.9 0.0 1.5 8.6 0.0 6.3 6 0 0 6 6 6 1 ATPase domain predominantly from Archaea AAA_24 PF13479.6 KXH46245.1 - 9.7e-07 28.7 2.2 1.7 8.3 0.1 6.6 6 1 1 7 7 7 1 AAA domain AAA_19 PF13245.6 KXH46245.1 - 1.2e-06 28.9 8.8 5 7.4 0.0 6.5 6 1 0 6 6 5 0 AAA domain DUF815 PF05673.13 KXH46245.1 - 1.8e-06 27.3 1.8 0.91 8.6 0.0 5.2 5 0 0 5 5 5 1 Protein of unknown function (DUF815) PduV-EutP PF10662.9 KXH46245.1 - 2.6e-06 27.2 2.5 0.1 12.3 0.0 4.9 5 0 0 5 5 5 2 Ethanolamine utilisation - propanediol utilisation Viral_helicase1 PF01443.18 KXH46245.1 - 2e-05 24.5 0.3 0.71 9.6 0.0 5.4 6 0 0 6 6 5 1 Viral (Superfamily 1) RNA helicase TniB PF05621.11 KXH46245.1 - 4e-05 23.1 0.6 12 5.3 0.0 6.2 7 0 0 7 7 7 0 Bacterial TniB protein dNK PF01712.19 KXH46245.1 - 4.2e-05 23.5 3.7 20 5.0 0.0 5.7 5 0 0 5 5 5 0 Deoxynucleoside kinase cobW PF02492.19 KXH46245.1 - 4.2e-05 23.2 6.0 3.4 7.2 0.0 5.9 6 0 0 6 6 6 0 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 KXH46245.1 - 0.0001 22.3 0.4 48 4.1 0.0 6.0 5 0 0 5 5 5 0 50S ribosome-binding GTPase CbiA PF01656.23 KXH46245.1 - 0.00011 22.2 0.0 5 7.2 0.0 4.6 4 0 0 4 4 4 0 CobQ/CobB/MinD/ParA nucleotide binding domain TIP49 PF06068.13 KXH46245.1 - 0.00019 20.8 0.8 6.9 5.8 0.0 4.7 5 0 0 5 5 5 0 TIP49 P-loop domain Roc PF08477.13 KXH46245.1 - 0.00066 19.9 5.1 8.2 6.7 0.1 5.8 6 0 0 6 6 5 0 Ras of Complex, Roc, domain of DAPkinase CPT PF07931.12 KXH46245.1 - 0.0013 18.6 2.5 34 4.2 0.0 6.3 7 1 0 7 7 4 0 Chloramphenicol phosphotransferase-like protein ATPase PF06745.13 KXH46245.1 - 0.0014 18.0 4.1 14 4.9 0.0 5.4 6 0 0 6 6 5 0 KaiC ATP_bind_1 PF03029.17 KXH46245.1 - 0.0015 18.4 4.4 22 4.7 0.0 5.7 6 0 0 6 6 6 0 Conserved hypothetical ATP binding protein NB-ARC PF00931.22 KXH46245.1 - 0.002 17.4 7.7 5.1 6.2 0.0 5.9 7 0 0 7 7 5 0 NB-ARC domain AAA_9 PF12781.7 KXH46245.1 - 0.01 15.0 0.0 0.7 9.0 0.0 3.5 4 0 0 4 4 4 0 ATP-binding dynein motor region MeaB PF03308.16 KXH46245.1 - 0.013 14.6 2.2 14 4.5 0.0 3.6 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB KTI12 PF08433.10 KXH46245.1 - 0.015 14.8 0.0 0.95 8.9 0.0 3.6 3 0 0 3 3 3 0 Chromatin associated protein KTI12 DEAD PF00270.29 KXH46245.1 - 0.017 14.9 0.7 3.8 7.3 0.0 3.6 4 0 0 4 4 3 0 DEAD/DEAH box helicase GAF_2 PF13185.6 KXH46245.1 - 0.027 14.8 0.0 0.33 11.2 0.0 3.0 2 0 0 2 2 1 0 GAF domain DAP3 PF10236.9 KXH46245.1 - 0.045 12.9 5.9 3.2 6.8 0.0 4.6 5 0 0 5 5 5 0 Mitochondrial ribosomal death-associated protein 3 Ploopntkinase3 PF18751.1 KXH46245.1 - 0.047 13.6 0.2 22 4.9 0.0 4.0 4 0 0 4 4 4 0 P-loop Nucleotide Kinase3 KAP_NTPase PF07693.14 KXH46245.1 - 0.053 12.8 0.1 19 4.3 0.0 4.6 6 0 0 6 6 5 0 KAP family P-loop domain PRK PF00485.18 KXH46245.1 - 0.073 12.8 0.1 36 4.0 0.0 4.2 6 0 0 6 6 3 0 Phosphoribulokinase / Uridine kinase family SRPRB PF09439.10 KXH46245.1 - 0.082 12.3 2.4 23 4.4 0.0 4.7 6 0 0 6 6 4 0 Signal recognition particle receptor beta subunit tRNA_lig_kinase PF08303.11 KXH46245.1 - 0.24 11.5 0.9 1.3 9.1 0.1 2.5 2 0 0 2 2 2 0 tRNA ligase kinase domain Hat1_N PF10394.9 KXH46246.1 - 9.4e-46 156.0 0.0 2.2e-45 154.7 0.0 1.7 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_10 PF13673.7 KXH46246.1 - 0.0013 18.7 0.0 0.0026 17.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXH46246.1 - 0.0025 18.0 0.0 0.0056 16.9 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXH46246.1 - 0.071 13.6 0.0 0.16 12.5 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Zip PF02535.22 KXH46247.1 - 8.5e-30 104.1 6.0 2.7e-26 92.6 3.1 2.5 2 1 0 2 2 2 2 ZIP Zinc transporter Bim_N PF06773.11 KXH46248.1 - 0.069 12.8 1.4 1.6 8.5 0.0 3.1 3 0 0 3 3 3 0 Bim protein N-terminus WD40 PF00400.32 KXH46249.1 - 2.6e-37 126.2 22.1 1.9e-07 31.6 0.2 7.2 6 0 0 6 6 6 6 WD domain, G-beta repeat F-box-like PF12937.7 KXH46249.1 - 1.2e-12 47.5 0.9 2.4e-12 46.5 0.9 1.5 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 KXH46249.1 - 8.4e-09 35.6 1.7 0.18 12.1 0.0 5.6 1 1 5 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KXH46249.1 - 2e-06 26.8 7.4 0.19 10.4 0.1 5.8 2 2 4 6 6 6 3 Nucleoporin Nup120/160 F-box PF00646.33 KXH46249.1 - 7.6e-06 25.7 2.5 1.5e-05 24.7 2.5 1.5 1 0 0 1 1 1 1 F-box domain WD40_like PF17005.5 KXH46249.1 - 0.0026 17.2 0.0 0.081 12.2 0.0 2.4 2 1 0 2 2 2 1 WD40-like domain PQQ_3 PF13570.6 KXH46249.1 - 0.0071 16.8 1.0 16 6.1 0.0 4.7 5 0 0 5 5 5 1 PQQ-like domain PQQ_2 PF13360.6 KXH46249.1 - 0.098 12.2 3.8 2 8.0 3.6 3.1 1 1 1 2 2 2 0 PQQ-like domain PALB2_WD40 PF16756.5 KXH46249.1 - 0.12 11.2 3.2 8.9 5.1 0.0 3.4 3 1 1 4 4 4 0 Partner and localizer of BRCA2 WD40 domain E1_dh PF00676.20 KXH46250.1 - 6e-112 373.5 0.4 7.4e-112 373.1 0.4 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 KXH46250.1 - 0.0027 17.0 0.6 0.004 16.4 0.1 1.5 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase DNA_ligase_A_M PF01068.21 KXH46251.1 - 3.4e-59 199.9 0.9 5.2e-47 160.1 0.3 2.4 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KXH46251.1 - 1.8e-43 148.8 0.0 5.7e-43 147.2 0.0 1.9 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 KXH46251.1 - 3.5e-29 101.3 0.0 1.8e-28 99.1 0.0 2.3 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 KXH46251.1 - 1.1e-05 25.7 0.1 2.1e-05 24.9 0.1 1.5 1 0 0 1 1 1 1 RNA ligase Peptidase_S9 PF00326.21 KXH46252.1 - 0.00065 19.2 0.0 0.0012 18.4 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KXH46252.1 - 0.0066 15.7 0.0 0.012 14.8 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF676 PF05057.14 KXH46252.1 - 0.087 12.3 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Zn_clus PF00172.18 KXH46306.1 - 5.7e-07 29.6 9.6 5.7e-07 29.6 9.6 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXH46306.1 - 6e-05 22.2 0.6 0.00013 21.1 0.6 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF2150 PF09920.9 KXH46306.1 - 0.16 12.0 0.0 5.8 6.9 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2150) adh_short PF00106.25 KXH46307.1 - 8.8e-35 119.9 0.0 6.8e-34 117.0 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXH46307.1 - 5.8e-29 101.3 0.0 1.2e-17 64.3 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH46307.1 - 0.017 15.0 0.0 1.5 8.7 0.0 2.1 2 0 0 2 2 2 0 KR domain UPF0146 PF03686.13 KXH46307.1 - 0.18 11.7 0.0 0.37 10.7 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) zf-C3HC PF07967.13 KXH46307.1 - 0.21 11.6 0.0 0.36 10.9 0.0 1.3 1 0 0 1 1 1 0 C3HC zinc finger-like Peptidase_S8 PF00082.22 KXH46308.1 - 9.8e-37 126.8 0.0 2.1e-36 125.7 0.0 1.5 1 1 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 KXH46308.1 - 7.4e-10 39.5 1.4 7.4e-10 39.5 1.4 1.9 2 0 0 2 2 2 1 Fn3-like domain FlgD_ig PF13860.6 KXH46308.1 - 0.00075 19.3 2.4 0.0011 18.7 0.1 2.5 2 0 0 2 2 2 1 FlgD Ig-like domain fn3_6 PF17766.1 KXH46308.1 - 0.0076 16.4 1.3 0.36 11.0 0.3 3.0 2 0 0 2 2 2 1 Fibronectin type-III domain p450 PF00067.22 KXH46310.1 - 1.7e-70 238.1 0.0 2.1e-70 237.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 TraB PF01963.17 KXH46310.1 - 0.12 12.2 0.1 0.77 9.6 0.0 2.0 2 0 0 2 2 2 0 TraB family SF3a60_bindingd PF12108.8 KXH46310.1 - 0.17 11.8 0.3 0.36 10.7 0.3 1.6 1 0 0 1 1 1 0 Splicing factor SF3a60 binding domain Pyr_redox_2 PF07992.14 KXH46311.1 - 1.4e-15 57.3 0.0 3.4e-12 46.2 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXH46311.1 - 4.7e-15 55.6 0.0 1.8e-13 50.4 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KXH46311.1 - 8.8e-13 47.5 0.0 1.8e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KXH46311.1 - 1.8e-12 47.1 0.0 2e-10 40.4 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KXH46311.1 - 6e-08 32.8 0.0 3.1e-07 30.5 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KXH46311.1 - 2.6e-07 30.7 0.3 0.0028 17.7 0.0 4.1 3 1 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.24 KXH46311.1 - 5.8e-07 29.4 1.0 0.022 14.4 0.1 3.2 2 1 0 3 3 3 2 FAD dependent oxidoreductase GIDA PF01134.22 KXH46311.1 - 0.0018 17.4 0.1 0.58 9.2 0.1 2.6 3 0 0 3 3 3 2 Glucose inhibited division protein A NAD_binding_7 PF13241.6 KXH46311.1 - 0.0096 16.4 0.0 1.3 9.5 0.0 2.8 2 1 0 2 2 2 1 Putative NAD(P)-binding Thi4 PF01946.17 KXH46311.1 - 0.014 14.6 0.0 1.2 8.3 0.0 2.4 2 0 0 2 2 2 0 Thi4 family Lycopene_cycl PF05834.12 KXH46311.1 - 0.017 14.2 0.0 0.063 12.3 0.0 2.0 2 1 0 2 2 2 0 Lycopene cyclase protein FAD_binding_3 PF01494.19 KXH46311.1 - 0.024 13.9 0.0 0.27 10.5 0.0 2.5 3 0 0 3 3 3 0 FAD binding domain FAD_binding_2 PF00890.24 KXH46311.1 - 0.026 13.6 0.1 0.056 12.5 0.1 1.5 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 KXH46311.1 - 0.046 12.4 0.1 0.13 10.9 0.1 1.8 2 0 0 2 2 2 0 HI0933-like protein FAD_oxidored PF12831.7 KXH46311.1 - 0.12 11.7 1.9 1.5 8.1 1.9 2.4 1 1 0 1 1 1 0 FAD dependent oxidoreductase Shikimate_DH PF01488.20 KXH46311.1 - 0.15 12.2 0.0 2.5 8.1 0.0 2.5 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase SnoaL_3 PF13474.6 KXH46312.1 - 9.1e-09 35.6 0.1 1.8e-08 34.7 0.1 1.5 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 KXH46312.1 - 0.0015 18.9 0.4 0.0028 18.0 0.2 1.6 1 1 1 2 2 2 1 Domain of unknown function (DUF4440) FAD_binding_4 PF01565.23 KXH46313.1 - 5.9e-25 87.6 4.4 1.2e-24 86.6 4.4 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KXH46313.1 - 2.7e-09 37.0 0.0 4.8e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 Berberine and berberine like PI-PLC-X PF00388.19 KXH46354.1 - 1.4e-57 193.3 0.0 2.4e-57 192.6 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 KXH46354.1 - 2.4e-40 137.5 0.0 4.3e-40 136.6 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 KXH46354.1 - 0.00026 21.2 0.1 0.001 19.3 0.0 2.1 2 0 0 2 2 2 1 C2 domain Cupin_2 PF07883.11 KXH46355.1 - 0.00015 21.4 0.2 0.00019 21.1 0.2 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_7 PF12973.7 KXH46355.1 - 0.037 13.9 0.0 0.084 12.8 0.0 1.5 1 1 0 1 1 1 0 ChrR Cupin-like domain SBP_bac_6 PF13343.6 KXH46358.1 - 3.9e-15 55.9 0.1 1.9e-14 53.7 0.1 1.8 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.6 KXH46358.1 - 2.2e-08 34.1 0.0 3.3e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 KXH46358.1 - 1.2e-07 31.8 0.4 2.3e-06 27.6 0.4 2.1 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 KXH46358.1 - 8e-06 26.0 0.1 0.066 13.2 0.0 2.2 2 0 0 2 2 2 2 Bacterial extracellular solute-binding protein Glyco_hydro_35 PF01301.19 KXH46359.1 - 1.1e-94 317.7 0.0 1.4e-94 317.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.9 KXH46359.1 - 2.9e-58 196.7 3.4 2.9e-58 196.7 3.4 1.8 2 0 0 2 2 2 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.6 KXH46359.1 - 1.2e-53 180.5 3.8 1.1e-26 93.6 0.0 3.1 3 0 0 3 3 3 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.6 KXH46359.1 - 2.6e-22 78.1 0.1 5.3e-22 77.2 0.1 1.5 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 Amidohydro_1 PF01979.20 KXH46360.1 - 1.2e-18 67.6 0.0 7.5e-18 64.9 0.0 2.0 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KXH46360.1 - 4.6e-05 23.1 0.0 0.0001 22.0 0.0 1.5 1 1 0 1 1 1 1 Amidohydrolase family Mid2 PF04478.12 KXH46361.1 - 7.8e-05 22.6 2.2 7.8e-05 22.6 2.2 2.4 1 1 2 3 3 3 1 Mid2 like cell wall stress sensor MAP17 PF15807.5 KXH46361.1 - 0.082 13.1 0.0 0.25 11.6 0.0 1.8 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 FeoB_associated PF12669.7 KXH46361.1 - 0.24 11.8 0.2 0.44 11.0 0.2 1.4 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein Macoilin PF09726.9 KXH46361.1 - 1.4 7.4 5.4 1.6 7.2 5.4 1.1 1 0 0 1 1 1 0 Macoilin family Plasmodium_Vir PF05795.11 KXH46361.1 - 5.4 6.3 9.4 8.4 5.7 9.4 1.4 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF725 PF05267.12 KXH46363.1 - 5.3 7.1 7.8 1.8 8.6 0.8 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF725) ApoO PF09769.9 KXH46363.1 - 8 6.4 7.9 1.6 8.7 1.4 3.0 2 0 0 2 2 2 0 Apolipoprotein O SRP-alpha_N PF04086.13 KXH46364.1 - 1.9e-89 300.4 0.0 2.6e-89 300.0 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.22 KXH46364.1 - 5.3e-53 179.6 0.4 2.6e-52 177.3 0.2 2.1 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP54_N PF02881.19 KXH46364.1 - 1.4e-08 34.9 0.1 4.3e-08 33.3 0.1 1.8 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain MeaB PF03308.16 KXH46364.1 - 1.3e-05 24.3 0.0 3.1e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 KXH46364.1 - 0.00085 19.1 0.2 0.0019 17.9 0.2 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 KXH46364.1 - 0.0017 18.8 0.6 0.0052 17.2 0.1 2.0 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 KXH46364.1 - 0.0043 16.7 0.1 0.012 15.3 0.1 1.7 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.6 KXH46364.1 - 0.0089 15.6 0.0 0.022 14.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 KXH46364.1 - 0.011 15.8 0.6 2 8.5 0.1 2.8 3 0 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain MMR_HSR1 PF01926.23 KXH46364.1 - 0.025 14.6 0.2 0.12 12.4 0.2 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.27 KXH46364.1 - 0.03 14.8 0.1 0.21 12.1 0.0 2.3 2 1 0 2 2 2 0 ABC transporter AAA_33 PF13671.6 KXH46364.1 - 0.049 13.8 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KXH46364.1 - 0.056 13.2 0.0 0.14 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.20 KXH46364.1 - 0.17 11.7 0.4 0.58 10.0 0.0 2.0 2 0 0 2 2 2 0 Adenylylsulphate kinase YIF1 PF03878.15 KXH46365.1 - 4e-101 337.5 0.7 5.1e-101 337.2 0.7 1.1 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.17 KXH46365.1 - 0.065 13.0 12.4 0.041 13.6 9.9 1.8 1 1 1 2 2 2 0 Yip1 domain Mpv17_PMP22 PF04117.12 KXH46366.1 - 2.4e-06 27.7 3.7 3.4e-06 27.2 0.2 2.4 2 0 0 2 2 2 1 Mpv17 / PMP22 family Methyltransf_15 PF09445.10 KXH46366.1 - 0.028 14.0 0.0 0.042 13.4 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase HATPase_c PF02518.26 KXH46367.1 - 2.5e-21 76.3 0.0 6.7e-21 74.9 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KXH46367.1 - 5.4e-17 62.0 1.1 6.3e-16 58.5 0.1 3.0 2 1 0 2 2 2 1 Response regulator receiver domain PAS_4 PF08448.10 KXH46367.1 - 3.8e-15 56.1 0.2 2.3e-05 24.6 0.0 4.3 4 1 0 4 4 4 2 PAS fold PAS_9 PF13426.7 KXH46367.1 - 9.4e-14 51.5 0.0 0.0031 17.7 0.0 3.8 3 0 0 3 3 3 3 PAS domain PAS PF00989.25 KXH46367.1 - 2.3e-12 46.9 0.0 0.0007 19.6 0.0 4.0 3 0 0 3 3 3 3 PAS fold HisKA PF00512.25 KXH46367.1 - 2.4e-08 33.9 0.0 9.8e-08 31.9 0.0 2.2 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.12 KXH46367.1 - 2.7e-06 27.6 0.1 0.2 12.0 0.0 3.6 3 0 0 3 3 3 2 PAS fold PAS_8 PF13188.7 KXH46367.1 - 0.00042 20.3 0.0 1.4 9.1 0.0 3.3 3 0 0 3 3 3 2 PAS domain GAF_3 PF13492.6 KXH46367.1 - 0.0066 16.8 0.0 0.046 14.1 0.0 2.3 2 0 0 2 2 2 1 GAF domain GAF_2 PF13185.6 KXH46367.1 - 0.0083 16.4 0.0 0.29 11.4 0.0 2.6 2 0 0 2 2 2 1 GAF domain GAF PF01590.26 KXH46367.1 - 0.012 16.2 0.0 0.69 10.5 0.0 2.7 2 0 0 2 2 2 0 GAF domain DUF370 PF04025.12 KXH46367.1 - 0.36 11.0 1.0 1.3 9.2 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF370) Dabb PF07876.12 KXH46368.1 - 2.1e-11 44.3 0.0 2.5e-11 44.1 0.0 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Polyketide_cyc2 PF10604.9 KXH46369.1 - 0.026 14.8 3.8 0.21 11.9 3.8 2.5 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport MFS_1 PF07690.16 KXH46370.1 - 1.6e-28 99.7 45.8 4.2e-26 91.7 45.2 3.4 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KXH46370.1 - 2e-06 26.5 17.6 3.1e-06 25.9 17.6 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 KXH46370.1 - 1.8 6.8 12.0 0.25 9.6 1.4 3.0 3 1 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family ketoacyl-synt PF00109.26 KXH46371.1 - 2.5e-76 256.6 0.1 5.1e-76 255.6 0.1 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 KXH46371.1 - 8.6e-56 189.7 0.0 1.4e-55 189.1 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 KXH46371.1 - 1.2e-49 169.2 0.0 2e-49 168.4 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 KXH46371.1 - 2.3e-44 151.4 1.7 2.7e-44 151.2 0.3 1.9 2 0 0 2 2 2 1 KR domain Ketoacyl-synt_C PF02801.22 KXH46371.1 - 1.9e-34 118.2 0.1 4.8e-34 116.9 0.1 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KXH46371.1 - 4.5e-18 65.7 0.0 2.7e-17 63.2 0.0 2.4 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 KXH46371.1 - 1.7e-12 47.2 0.1 4.6e-12 45.8 0.1 1.7 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXH46371.1 - 1.1e-10 41.5 0.2 3e-10 40.1 0.2 1.7 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Thiolase_N PF00108.23 KXH46371.1 - 0.00017 21.1 0.2 0.00038 19.9 0.2 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain ADH_N PF08240.12 KXH46371.1 - 0.0002 21.2 0.2 0.00046 20.0 0.2 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXH46371.1 - 0.035 14.1 0.1 0.2 11.6 0.1 2.3 2 0 0 2 2 2 0 Zinc-binding dehydrogenase ACP_syn_III PF08545.10 KXH46371.1 - 0.076 12.9 0.9 0.27 11.1 0.9 2.0 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GCN5L1 PF06320.13 KXH46382.1 - 2.3e-14 53.5 0.4 2.3e-14 53.5 0.4 1.4 2 0 0 2 2 2 1 GCN5-like protein 1 (GCN5L1) Rootletin PF15035.6 KXH46382.1 - 0.035 14.1 0.2 0.048 13.7 0.2 1.2 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion PRCC PF10253.9 KXH46382.1 - 0.037 14.8 12.1 0.05 14.4 12.1 1.2 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting SOG2 PF10428.9 KXH46382.1 - 1.4 8.0 15.1 1.6 7.9 15.1 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein TFIIA PF03153.13 KXH46382.1 - 2.2 8.2 13.4 2.7 7.9 13.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ndc1_Nup PF09531.10 KXH46382.1 - 5.4 5.6 12.7 6.2 5.4 12.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF1993 PF09351.10 KXH46383.1 - 1.5e-50 171.5 0.1 1.7e-50 171.3 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) DinB PF05163.12 KXH46383.1 - 0.028 14.3 0.0 0.05 13.5 0.0 1.4 1 1 0 1 1 1 0 DinB family DJ-1_PfpI PF01965.24 KXH46384.1 - 5.4e-06 26.3 0.0 1.9e-05 24.6 0.0 1.8 1 1 0 1 1 1 1 DJ-1/PfpI family SOG2 PF10428.9 KXH46385.1 - 4.6e-77 260.4 0.0 1.5e-52 179.5 0.0 3.9 4 1 0 5 5 5 2 RAM signalling pathway protein LRR_8 PF13855.6 KXH46385.1 - 3.3e-17 62.0 0.6 9.7e-09 34.9 0.1 2.6 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 KXH46385.1 - 4.8e-14 52.2 2.2 8.5e-06 26.0 0.2 3.7 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KXH46385.1 - 0.0025 17.7 3.6 1.7 8.9 0.1 4.1 3 0 0 3 3 3 2 Leucine Rich repeat LRR_1 PF00560.33 KXH46385.1 - 0.005 17.2 2.6 20 6.2 0.0 4.6 4 0 0 4 4 4 1 Leucine Rich Repeat DUF2408 PF10303.9 KXH46385.1 - 0.0095 16.5 0.1 0.093 13.3 0.0 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF2408) Helicase_C PF00271.31 KXH46386.1 - 7.5e-18 64.9 0.0 4.4e-15 56.0 0.0 2.6 2 0 0 2 2 2 2 Helicase conserved C-terminal domain DEAD PF00270.29 KXH46386.1 - 8.3e-16 58.2 0.0 1.7e-15 57.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 KXH46386.1 - 8.7e-14 52.0 1.6 2.5e-13 50.5 1.6 1.8 1 0 0 1 1 1 1 RecQ zinc-binding Pyr_redox_2 PF07992.14 KXH46387.1 - 6e-62 209.5 0.5 9.6e-62 208.9 0.5 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KXH46387.1 - 7.1e-33 113.2 1.0 1.3e-32 112.3 0.4 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KXH46387.1 - 6.5e-20 71.5 1.1 4.6e-19 68.8 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXH46387.1 - 7.2e-14 51.7 0.1 9.9e-14 51.3 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXH46387.1 - 1.2e-06 27.9 0.1 8.1e-05 21.9 0.0 2.3 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 KXH46387.1 - 0.00036 19.3 3.6 1.3 7.7 0.0 3.2 2 1 1 3 3 3 3 HI0933-like protein FAD_oxidored PF12831.7 KXH46387.1 - 0.0024 17.3 0.1 0.014 14.8 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 KXH46387.1 - 0.09 11.8 1.4 0.13 11.3 0.1 2.0 2 1 1 3 3 3 0 Glucose inhibited division protein A FAD_binding_2 PF00890.24 KXH46387.1 - 0.68 8.9 4.2 6.8 5.6 2.9 2.3 2 0 0 2 2 2 0 FAD binding domain MID_MedPIWI PF18296.1 KXH46388.1 - 0.094 12.5 0.1 0.11 12.3 0.1 1.1 1 0 0 1 1 1 0 MID domain of medPIWI MSP1_C PF07462.11 KXH46388.1 - 4.4 5.9 3.9 5.3 5.6 3.9 1.0 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Ribosomal_S8e PF01201.22 KXH46390.1 - 1.9e-55 186.8 2.0 2.6e-55 186.3 2.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S8e RabGAP-TBC PF00566.18 KXH46391.1 - 1.6e-50 171.8 1.7 2.3e-48 164.7 0.3 2.6 1 1 1 2 2 2 2 Rab-GTPase-TBC domain Cnn_1N PF07989.11 KXH46391.1 - 0.0006 19.9 3.9 0.0006 19.9 3.9 3.5 3 1 1 4 4 4 2 Centrosomin N-terminal motif 1 HALZ PF02183.18 KXH46391.1 - 0.0063 16.7 13.5 0.039 14.2 0.8 3.5 3 0 0 3 3 3 2 Homeobox associated leucine zipper Jnk-SapK_ap_N PF09744.9 KXH46391.1 - 0.0076 16.5 20.2 0.0076 16.5 20.2 3.3 2 1 1 3 3 3 1 JNK_SAPK-associated protein-1 KASH_CCD PF14662.6 KXH46391.1 - 0.039 13.8 25.8 0.1 12.4 25.8 1.8 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH FlaC_arch PF05377.11 KXH46391.1 - 0.4 11.1 12.6 1.2 9.6 2.3 3.4 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Cep57_MT_bd PF06657.13 KXH46391.1 - 1.7 9.2 11.8 0.83 10.1 3.3 2.8 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Z1 PF10593.9 KXH46391.1 - 7.1 6.1 10.5 5 6.6 7.2 2.3 2 0 0 2 2 2 0 Z1 domain bZIP_1 PF00170.21 KXH46391.1 - 9.6 6.4 24.1 2 8.6 3.4 4.0 3 1 0 3 3 3 0 bZIP transcription factor DUF913 PF06025.12 KXH46392.1 - 2.2e-131 438.2 0.0 2.2e-131 438.2 0.0 8.1 6 3 1 7 7 7 1 Domain of Unknown Function (DUF913) DUF908 PF06012.12 KXH46392.1 - 1.2e-118 396.7 2.8 1.2e-118 396.7 2.8 4.3 4 1 1 5 5 5 1 Domain of Unknown Function (DUF908) HECT PF00632.25 KXH46392.1 - 1.2e-93 314.0 0.0 2.8e-93 312.8 0.0 1.6 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) UBM PF14377.6 KXH46392.1 - 1.6e-25 87.7 19.0 2.4e-08 33.2 3.1 4.0 3 0 0 3 3 3 3 Ubiquitin binding region Pribosyl_synth PF14572.6 KXH46394.1 - 2.9e-43 148.0 0.5 1.7e-37 129.2 0.3 2.0 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 KXH46394.1 - 1.2e-16 60.7 0.4 1.6e-16 60.2 0.4 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KXH46394.1 - 0.0069 15.8 0.1 0.0092 15.4 0.1 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Ribosomal_S6e PF01092.19 KXH46395.1 - 3e-59 198.5 0.0 5.9e-59 197.5 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S6e Atg14 PF10186.9 KXH46395.1 - 3.4 6.7 8.6 4.4 6.3 8.6 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Ctf8 PF09696.10 KXH46396.1 - 1.2e-40 139.2 0.2 1.9e-40 138.5 0.2 1.4 1 1 0 1 1 1 1 Ctf8 Glyco_hydro_10 PF00331.20 KXH46397.1 - 5.2e-89 298.5 0.0 5.9e-89 298.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Diphthamide_syn PF01866.17 KXH46399.1 - 5e-117 390.7 0.0 5.8e-117 390.5 0.0 1.0 1 0 0 1 1 1 1 Putative diphthamide synthesis protein 3Beta_HSD PF01073.19 KXH46410.1 - 1.2e-22 80.3 0.0 2.2e-21 76.1 0.0 2.1 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KXH46410.1 - 1.1e-07 31.4 0.0 1.5e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 KXH46410.1 - 3.2e-05 23.5 0.0 7.5e-05 22.3 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KXH46410.1 - 0.044 13.7 0.0 0.069 13.1 0.0 1.3 1 0 0 1 1 1 0 KR domain DUF1480 PF07351.13 KXH46410.1 - 0.066 13.5 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1480) p450 PF00067.22 KXH46411.1 - 2.7e-40 138.5 0.0 3.5e-40 138.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Tubulin PF00091.25 KXH46412.1 - 8.5e-63 212.1 0.0 1.2e-62 211.6 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KXH46412.1 - 2.9e-45 153.5 0.0 4.3e-45 152.9 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KXH46412.1 - 8.7e-05 22.3 0.0 0.00016 21.4 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain RRM_1 PF00076.22 KXH46413.1 - 9.4e-12 44.6 0.3 2.5e-07 30.4 0.0 2.9 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RR_TM4-6 PF06459.12 KXH46413.1 - 4.1 7.1 30.8 9.1 6.0 30.8 1.6 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Peptidase_S64 PF08192.11 KXH46413.1 - 5.8 5.3 9.5 8.5 4.7 9.5 1.2 1 0 0 1 1 1 0 Peptidase family S64 Sds3 PF08598.11 KXH46414.1 - 1.5e-12 48.0 8.5 1.5e-12 48.0 8.5 2.6 2 1 0 2 2 2 1 Sds3-like VRP1 PF03538.14 KXH46414.1 - 0.069 12.5 0.1 0.12 11.8 0.1 1.3 1 0 0 1 1 1 0 Salmonella virulence plasmid 28.1kDa A protein Metal_resist PF13801.6 KXH46414.1 - 0.24 11.6 2.7 2.6 8.3 0.9 2.8 2 0 0 2 2 2 0 Heavy-metal resistance DUF3453 PF11935.8 KXH46415.1 - 1.8e-70 237.1 0.3 3.1e-70 236.4 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3453) CALCOCO1 PF07888.11 KXH46416.1 - 0.23 10.3 28.0 0.4 9.5 28.0 1.4 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like MCC-bdg_PDZ PF10506.9 KXH46416.1 - 1.8 8.6 7.9 13 5.9 0.1 4.1 4 0 0 4 4 4 0 PDZ domain of MCC-2 bdg protein for Usher syndrome TMEM234 PF10639.9 KXH46431.1 - 2.8e-15 56.4 0.0 4.1e-15 55.8 0.0 1.2 1 0 0 1 1 1 1 Putative transmembrane family 234 DUF3299 PF11736.8 KXH46431.1 - 0.39 10.7 0.1 0.39 10.7 0.1 1.5 1 1 0 2 2 2 0 Protein of unknown function (DUF3299) DUF2011 PF09428.10 KXH46432.1 - 0.013 15.7 0.1 1.2 9.5 0.0 2.2 1 1 1 2 2 2 0 Fungal protein of unknown function (DUF2011) Proteasome PF00227.26 KXH46433.1 - 4.6e-46 156.7 0.0 6.5e-46 156.2 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KXH46433.1 - 1e-13 50.7 0.3 2.1e-13 49.6 0.3 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF2373 PF10180.9 KXH46434.1 - 8.8e-23 79.9 0.2 1.5e-22 79.2 0.2 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) Nop14 PF04147.12 KXH46434.1 - 1.5 7.0 37.5 2.4 6.3 37.5 1.3 1 0 0 1 1 1 0 Nop14-like family PhyH PF05721.13 KXH46435.1 - 8.5e-62 209.1 0.0 1.1e-61 208.8 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.6 KXH46435.1 - 0.013 15.9 0.0 0.023 15.1 0.0 1.4 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase Claudin_2 PF13903.6 KXH46436.1 - 0.033 13.9 7.7 0.64 9.7 7.7 2.1 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction SIS PF01380.22 KXH46437.1 - 1.6e-10 41.0 0.4 5.8e-10 39.1 0.4 1.9 1 1 0 1 1 1 1 SIS domain C2 PF00168.30 KXH46438.1 - 2.6e-16 59.8 0.0 6.2e-16 58.6 0.0 1.7 2 0 0 2 2 2 1 C2 domain Peptidase_M24 PF00557.24 KXH46439.1 - 2e-39 135.5 0.0 2.6e-39 135.1 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 YL1 PF05764.13 KXH46439.1 - 0.0072 16.5 3.7 0.01 16.0 3.7 1.1 1 0 0 1 1 1 1 YL1 nuclear protein Med3 PF11593.8 KXH46439.1 - 0.093 11.9 3.6 0.17 11.0 3.6 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal TSGP1 PF07771.11 KXH46439.1 - 0.51 10.5 5.0 1.1 9.5 5.0 1.5 1 0 0 1 1 1 0 Tick salivary peptide group 1 Ank_2 PF12796.7 KXH46440.1 - 7.3e-44 148.3 11.5 1.1e-12 48.4 0.1 6.0 4 1 1 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXH46440.1 - 4.7e-39 132.3 8.9 3.6e-07 30.6 0.0 7.8 4 1 3 7 7 7 7 Ankyrin repeats (many copies) Ank PF00023.30 KXH46440.1 - 7e-30 102.2 26.4 0.00048 20.5 0.2 11.0 11 0 0 11 11 10 7 Ankyrin repeat Ank_3 PF13606.6 KXH46440.1 - 4.2e-28 94.3 11.2 0.0017 18.6 0.1 10.6 10 0 0 10 10 9 6 Ankyrin repeat Ank_5 PF13857.6 KXH46440.1 - 1.8e-24 85.4 11.3 6.4e-05 23.2 0.1 6.9 4 1 2 6 6 6 6 Ankyrin repeats (many copies) NACHT PF05729.12 KXH46440.1 - 2.7e-06 27.4 0.0 2e-05 24.6 0.0 2.3 1 1 0 1 1 1 1 NACHT domain PNP_UDP_1 PF01048.20 KXH46440.1 - 0.00015 21.1 0.0 0.00085 18.6 0.0 2.1 2 0 0 2 2 2 1 Phosphorylase superfamily AAA_16 PF13191.6 KXH46440.1 - 0.002 18.5 0.0 0.011 16.2 0.0 2.3 1 0 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 KXH46440.1 - 0.003 18.1 0.0 0.011 16.2 0.0 2.0 2 0 0 2 2 2 1 ABC transporter RNA_helicase PF00910.22 KXH46440.1 - 0.0047 17.3 0.0 0.01 16.2 0.0 1.6 1 0 0 1 1 1 1 RNA helicase UvrD-helicase PF00580.21 KXH46440.1 - 0.019 14.5 0.0 0.051 13.1 0.0 1.7 1 1 0 1 1 1 0 UvrD/REP helicase N-terminal domain AAA PF00004.29 KXH46440.1 - 0.037 14.5 0.0 0.11 13.0 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 KXH46440.1 - 0.047 13.6 0.0 0.097 12.6 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_19 PF13245.6 KXH46440.1 - 0.056 13.8 0.0 0.17 12.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain Rsd_AlgQ PF04353.13 KXH46440.1 - 0.063 13.2 0.1 2.7 7.9 0.0 3.1 3 0 0 3 3 3 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ NB-ARC PF00931.22 KXH46440.1 - 0.073 12.2 0.0 0.16 11.2 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_7 PF12775.7 KXH46440.1 - 0.2 11.2 0.0 0.5 9.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region RRM_1 PF00076.22 KXH46442.1 - 5.8e-19 67.7 0.1 2.3e-11 43.4 0.0 4.0 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KXH46442.1 - 0.0084 16.2 0.1 0.21 11.7 0.1 2.5 2 0 0 2 2 2 1 RNA recognition motif Nup35_RRM_2 PF14605.6 KXH46442.1 - 0.053 13.5 0.0 0.15 12.1 0.0 1.7 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Cut8 PF08559.10 KXH46443.1 - 3.8e-76 255.9 0.0 4.8e-76 255.5 0.0 1.1 1 0 0 1 1 1 1 Cut8, nuclear proteasome tether protein AP_endonuc_2 PF01261.24 KXH46443.1 - 0.045 13.2 0.0 0.075 12.5 0.0 1.3 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Rad52_Rad22 PF04098.15 KXH46444.1 - 1.9e-60 203.3 0.0 2.5e-60 202.9 0.0 1.1 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein DUF3328 PF11807.8 KXH46446.1 - 3.8e-14 53.0 3.8 1.5e-13 51.1 1.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3328) LRRC37AB_C PF14914.6 KXH46446.1 - 0.037 13.9 0.1 0.058 13.3 0.1 1.2 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain DUF3328 PF11807.8 KXH46447.1 - 2e-33 116.0 1.2 2.7e-33 115.6 1.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Fungal_trans_2 PF11951.8 KXH46450.1 - 2.7e-22 79.1 3.3 8.5e-22 77.5 3.3 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain UTP15_C PF09384.10 KXH46451.1 - 7.8e-47 158.7 0.0 1.2e-46 158.0 0.0 1.3 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.32 KXH46451.1 - 1.8e-18 66.5 6.4 1.6e-05 25.6 0.1 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXH46451.1 - 4.1e-07 30.2 0.0 0.18 12.2 0.0 4.4 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KXH46451.1 - 0.0058 15.3 0.4 2.6 6.6 0.0 2.6 2 1 1 3 3 3 2 Nucleoporin Nup120/160 RAB3GAP2_N PF14655.6 KXH46451.1 - 0.038 13.3 0.0 0.73 9.0 0.0 2.1 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Pinin_SDK_memA PF04696.13 KXH46451.1 - 0.045 13.8 3.1 0.073 13.1 3.1 1.3 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region WD40_3 PF15911.5 KXH46451.1 - 0.079 13.0 0.0 11 6.1 0.0 2.8 3 0 0 3 3 3 0 WD domain, G-beta repeat PQQ_3 PF13570.6 KXH46451.1 - 1.7 9.2 4.9 1.4e+02 3.1 0.0 4.9 7 0 0 7 7 7 0 PQQ-like domain Gln-synt_C PF00120.24 KXH46452.1 - 6.9e-15 54.9 0.0 1.5e-10 40.7 0.0 2.1 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 KXH46452.1 - 8.9e-14 51.0 0.0 1.9e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Fungal_trans PF04082.18 KXH46486.1 - 0.00035 19.7 0.0 0.0012 18.0 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain FPN1 PF06963.12 KXH46487.1 - 2.4e-117 392.2 10.8 2.7e-117 392.0 10.8 1.0 1 0 0 1 1 1 1 Ferroportin1 (FPN1) PQ-loop PF04193.14 KXH46488.1 - 9.2e-37 124.6 2.8 5.1e-19 67.8 0.1 2.6 2 0 0 2 2 2 2 PQ loop repeat DUF1773 PF08593.10 KXH46488.1 - 0.069 14.2 0.1 0.13 13.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function Exo_endo_phos PF03372.23 KXH46490.1 - 8.2e-10 38.6 0.0 3e-09 36.7 0.0 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 KXH46490.1 - 0.0093 15.8 0.0 0.017 15.0 0.0 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Trm5_N PF18093.1 KXH46491.1 - 0.26 11.2 0.4 1.8 8.6 0.1 2.2 2 0 0 2 2 2 0 tRNA methyltransferase 5 N-terminal domain Lactonase PF10282.9 KXH46492.1 - 1.2e-83 281.3 0.2 1.5e-83 281.0 0.2 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller FAD_binding_4 PF01565.23 KXH46493.1 - 2.7e-20 72.5 0.6 6.2e-20 71.4 0.6 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KXH46493.1 - 2.4e-08 34.0 1.2 5.2e-08 32.9 1.2 1.5 1 0 0 1 1 1 1 Berberine and berberine like NAD_kinase PF01513.21 KXH46495.1 - 4.8e-51 173.7 0.0 2.2e-50 171.5 0.0 1.8 1 1 0 1 1 1 1 ATP-NAD kinase KR PF08659.10 KXH46496.1 - 3.7e-59 199.7 0.3 9.1e-59 198.4 0.3 1.7 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 KXH46496.1 - 2.4e-58 197.7 0.0 7.3e-58 196.2 0.0 1.8 2 0 0 2 2 2 1 Polyketide synthase dehydratase ketoacyl-synt PF00109.26 KXH46496.1 - 2.5e-57 194.4 0.2 8.7e-57 192.6 0.0 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 KXH46496.1 - 3.2e-57 194.4 0.5 5e-57 193.8 0.5 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KXH46496.1 - 6.9e-29 100.3 1.4 1.9e-28 98.9 0.4 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N_2 PF13602.6 KXH46496.1 - 4.8e-20 73.0 0.0 2.8e-18 67.3 0.0 2.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.12 KXH46496.1 - 1.9e-18 67.0 0.0 6e-18 65.4 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.26 KXH46496.1 - 4.4e-14 52.6 0.3 1.7e-13 50.7 0.3 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 KXH46496.1 - 1.7e-12 47.2 0.4 2.1e-11 43.7 0.0 2.4 2 0 0 2 2 2 1 short chain dehydrogenase Methyltransf_23 PF13489.6 KXH46496.1 - 2.5e-11 43.7 0.0 1e-10 41.7 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH46496.1 - 6.7e-09 36.3 0.0 3.6e-08 34.0 0.0 2.4 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH46496.1 - 2.7e-08 33.7 0.0 7.1e-08 32.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain ADH_N PF08240.12 KXH46496.1 - 6.8e-08 32.4 0.1 1.7e-07 31.1 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_11 PF08241.12 KXH46496.1 - 1.5e-07 31.9 0.0 5.5e-07 30.2 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 KXH46496.1 - 4.1e-05 23.9 0.1 0.00023 21.5 0.1 2.3 2 0 0 2 2 2 1 Phosphopantetheine attachment site Thiolase_N PF00108.23 KXH46496.1 - 0.00022 20.7 3.3 0.00043 19.7 0.1 2.7 3 0 0 3 3 3 1 Thiolase, N-terminal domain KAsynt_C_assoc PF16197.5 KXH46496.1 - 0.0014 19.0 0.0 0.0038 17.7 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension ACP_syn_III PF08545.10 KXH46496.1 - 0.03 14.2 0.8 0.09 12.6 0.8 1.8 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Ubie_methyltran PF01209.18 KXH46496.1 - 0.041 13.2 0.0 0.13 11.6 0.0 1.8 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family DUF3328 PF11807.8 KXH46497.1 - 1.1e-17 64.5 5.4 5.7e-17 62.2 5.4 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) Thioesterase PF00975.20 KXH46498.1 - 1.6e-11 44.8 0.0 2.6e-11 44.1 0.0 1.6 1 1 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.7 KXH46498.1 - 5.2e-07 30.5 0.7 6.3e-07 30.2 0.7 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 KXH46498.1 - 0.0027 17.6 0.0 0.0035 17.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2974 PF11187.8 KXH46498.1 - 0.033 13.7 0.0 0.053 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DUF2235 PF09994.9 KXH46498.1 - 0.099 12.0 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) Lipase_3 PF01764.25 KXH46498.1 - 0.15 11.9 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF3328 PF11807.8 KXH46499.1 - 6.2e-15 55.6 3.8 1.5e-14 54.3 3.8 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) Circo_capsid PF02443.15 KXH46499.1 - 0.05 13.2 0.0 0.37 10.4 0.0 2.1 2 0 0 2 2 2 0 Circovirus capsid protein DUF4939 PF16297.5 KXH46501.1 - 0.0027 17.5 1.4 24 4.9 0.0 5.5 2 2 3 6 6 6 1 Domain of unknown function (DUF4939) NosL PF05573.12 KXH46501.1 - 0.0086 16.4 0.1 0.2 12.0 0.0 2.9 1 1 1 2 2 2 1 NosL DUF5055 PF16478.5 KXH46501.1 - 0.016 15.5 15.1 14 5.9 0.2 5.6 1 1 5 6 6 6 0 Domain of unknown function (DUF5055) PG_binding_4 PF12229.8 KXH46501.1 - 0.077 13.3 0.4 23 5.3 0.0 3.5 3 1 1 4 4 4 0 Putative peptidoglycan binding domain Vsr PF03852.15 KXH46501.1 - 0.46 10.4 2.9 29 4.6 0.1 3.6 1 1 0 3 3 3 0 DNA mismatch endonuclease Vsr DUF3622 PF12286.8 KXH46501.1 - 0.71 10.3 9.5 15 6.0 0.2 4.3 1 1 4 5 5 5 0 Protein of unknown function (DUF3622) RNase_J_C PF17770.1 KXH46501.1 - 2 9.5 8.1 34 5.6 0.0 5.3 3 3 3 6 6 6 0 Ribonuclease J C-terminal domain MFS_1 PF07690.16 KXH46504.1 - 2.5e-36 125.4 40.5 1.2e-34 119.8 37.6 2.5 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 KXH46504.1 - 1.7e-07 30.9 1.7 1.7e-07 30.9 1.7 3.6 2 2 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB DUF2583 PF10762.9 KXH46504.1 - 0.98 9.9 7.4 0.33 11.4 0.8 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2583) HTH_51 PF18558.1 KXH46505.1 - 3.3e-29 100.6 0.0 7.6e-29 99.4 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain Methyltransf_12 PF08242.12 KXH46505.1 - 2e-16 60.5 0.0 6.9e-16 58.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH46505.1 - 5.1e-12 46.4 0.0 9.5e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH46505.1 - 1.1e-10 42.0 0.0 1.9e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXH46505.1 - 2.2e-09 37.4 0.0 3.8e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXH46505.1 - 3.4e-06 26.6 0.0 5.2e-05 22.7 0.0 2.2 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 KXH46505.1 - 1e-05 25.4 0.0 1.6e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DUF938 PF06080.12 KXH46505.1 - 0.032 14.0 0.0 0.056 13.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_33 PF10017.9 KXH46505.1 - 0.13 11.4 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent NPL4 PF05021.15 KXH46505.1 - 0.16 11.3 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 NPL4 family ADH_zinc_N PF00107.26 KXH46506.1 - 7.7e-12 45.3 0.1 1.4e-11 44.5 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXH46506.1 - 2.2e-07 30.7 0.0 2.2e-06 27.5 0.0 2.3 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain PS-DH PF14765.6 KXH46507.1 - 1.1e-62 212.0 0.0 1.6e-62 211.4 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase ketoacyl-synt PF00109.26 KXH46507.1 - 2e-56 191.4 0.0 3.8e-56 190.5 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KXH46507.1 - 2.4e-52 177.4 0.0 5.4e-52 176.3 0.0 1.6 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.21 KXH46507.1 - 4e-51 174.4 0.0 7.5e-51 173.5 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KXH46507.1 - 7e-32 109.9 0.0 2.9e-31 107.9 0.0 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KXH46507.1 - 2.4e-22 79.5 0.0 4.9e-22 78.5 0.0 1.6 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension PP-binding PF00550.25 KXH46507.1 - 4.9e-08 33.2 0.1 1.6e-07 31.6 0.1 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.25 KXH46507.1 - 6.3e-08 32.3 0.0 1.8e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXH46507.1 - 5e-05 23.0 0.0 0.00014 21.5 0.0 1.7 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Thiolase_N PF00108.23 KXH46507.1 - 0.0035 16.8 0.7 0.0094 15.3 0.7 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain Sacchrp_dh_NADP PF03435.18 KXH46507.1 - 0.017 15.4 0.0 0.067 13.4 0.0 2.1 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain ACP_syn_III PF08545.10 KXH46507.1 - 0.14 12.1 1.3 0.35 10.7 1.3 1.6 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III EamA PF00892.20 KXH46508.1 - 4.8e-14 52.7 34.8 1.4e-09 38.2 7.0 2.1 2 0 0 2 2 2 2 EamA-like transporter family p450 PF00067.22 KXH46509.1 - 5.3e-30 104.6 0.0 7.4e-30 104.1 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 Zn_clus PF00172.18 KXH46510.1 - 7.1e-10 38.9 6.4 1.8e-09 37.5 6.4 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXH46510.1 - 0.044 12.8 0.1 0.077 12.0 0.1 1.4 1 0 0 1 1 1 0 Fungal specific transcription factor domain Methyltransf_12 PF08242.12 KXH46511.1 - 6.9e-06 26.7 0.0 1.5e-05 25.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH46511.1 - 2.2e-05 25.1 0.0 8e-05 23.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH46511.1 - 0.0002 22.0 0.0 0.00077 20.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Peptidase_S41 PF03572.18 KXH46512.1 - 7.2e-09 35.4 0.0 1.4e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase family S41 Alpha-amylase PF00128.24 KXH46513.1 - 1.2e-24 87.5 3.4 4.8e-24 85.5 3.4 1.8 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.16 KXH46513.1 - 4.7e-05 21.8 0.2 0.022 13.0 0.0 3.0 3 0 0 3 3 3 3 Glycosyl hydrolase family 70 DUF1939 PF09154.10 KXH46513.1 - 0.056 13.6 0.0 0.13 12.5 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1939) Condensation PF00668.20 KXH46514.1 - 3.7e-170 566.5 0.8 3.9e-61 207.1 0.0 5.5 6 0 0 6 6 6 5 Condensation domain AMP-binding PF00501.28 KXH46514.1 - 6.2e-143 476.4 0.0 5.3e-73 246.0 0.0 2.3 2 0 0 2 2 2 2 AMP-binding enzyme PP-binding PF00550.25 KXH46514.1 - 1.9e-27 95.4 0.6 5.9e-11 42.6 0.0 5.3 5 0 0 5 5 5 4 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KXH46514.1 - 0.0019 19.1 0.0 0.079 14.0 0.0 2.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain O-FucT PF10250.9 KXH46515.1 - 5.8e-11 42.7 0.2 2.7e-09 37.2 0.2 2.7 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Hjc PF01870.18 KXH46515.1 - 0.019 14.9 0.0 0.046 13.7 0.0 1.6 1 1 0 1 1 1 0 Archaeal holliday junction resolvase (hjc) DUF1772 PF08592.11 KXH46516.1 - 0.15 12.4 0.0 1.3 9.3 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) CDH-cyt PF16010.5 KXH46517.1 - 1.5e-52 177.9 0.2 3.6e-52 176.7 0.2 1.7 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase GMC_oxred_N PF00732.19 KXH46517.1 - 2.3e-28 99.4 0.0 6.5e-28 98.0 0.0 1.8 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXH46517.1 - 2.9e-19 70.0 0.1 2.9e-19 70.0 0.1 1.9 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KXH46517.1 - 3e-09 36.5 0.1 1e-06 28.1 0.2 2.1 2 0 0 2 2 2 2 FAD binding domain HI0933_like PF03486.14 KXH46517.1 - 2.8e-07 29.6 1.4 9.2e-07 27.9 0.2 2.0 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.14 KXH46517.1 - 6.9e-07 28.8 0.1 5.1e-06 25.9 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXH46517.1 - 8.2e-07 28.9 0.3 0.0004 20.1 0.2 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KXH46517.1 - 1.3e-06 28.1 0.6 2.3e-06 27.2 0.6 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KXH46517.1 - 3e-06 26.7 0.4 5.3e-06 25.9 0.4 1.4 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 KXH46517.1 - 7.2e-05 22.0 0.7 0.00017 20.8 0.7 1.6 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 KXH46517.1 - 0.00011 22.3 1.4 0.00021 21.5 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 KXH46517.1 - 0.00014 21.0 0.0 0.00031 19.9 0.0 1.5 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 KXH46517.1 - 0.00034 20.0 0.7 0.0023 17.2 1.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXH46517.1 - 0.0012 18.1 0.2 0.0022 17.3 0.2 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 KXH46517.1 - 0.0015 19.1 0.1 0.005 17.4 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KXH46517.1 - 0.014 14.3 0.2 0.024 13.5 0.2 1.3 1 0 0 1 1 1 0 Tryptophan halogenase GMC_oxred_N PF00732.19 KXH46518.1 - 1.7e-55 188.5 0.1 2.1e-55 188.2 0.1 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXH46518.1 - 2.1e-37 128.8 0.0 4.1e-37 127.9 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KXH46518.1 - 5e-05 22.5 0.0 8e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 KXH46518.1 - 0.0016 18.1 0.1 0.0084 15.7 0.1 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXH46518.1 - 0.0041 16.4 0.1 0.025 13.8 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXH46518.1 - 0.018 15.3 0.7 0.055 13.7 0.7 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KXH46518.1 - 0.082 12.1 0.1 1.6 7.9 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXH46518.1 - 0.12 11.6 0.0 0.26 10.5 0.0 1.5 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.24 KXH46518.1 - 0.14 11.2 0.3 0.21 10.6 0.3 1.2 1 0 0 1 1 1 0 FAD binding domain DUF5381 PF17353.2 KXH46519.1 - 1.7 8.4 7.4 0.088 12.5 1.5 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5381) Fungal_trans_2 PF11951.8 KXH46520.1 - 4.1e-23 81.8 1.0 6.3e-23 81.2 1.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH46520.1 - 1.4e-05 25.1 8.4 2.7e-05 24.2 8.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CAP PF00188.26 KXH46521.1 - 8.4e-18 65.4 0.2 1.3e-17 64.8 0.2 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family FtsH_ext PF06480.15 KXH46521.1 - 0.42 11.0 6.4 1.6 9.1 0.6 2.8 2 2 0 2 2 2 0 FtsH Extracellular Tubulin PF00091.25 KXH46522.1 - 8.5e-71 238.2 0.0 2.6e-70 236.7 0.0 1.7 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KXH46522.1 - 2.4e-38 131.1 0.1 3.8e-38 130.5 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 KXH46522.1 - 4.7e-07 30.1 0.0 1e-06 29.0 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 KXH46522.1 - 0.0051 16.5 0.0 0.0097 15.6 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 KXH46522.1 - 0.025 13.8 0.0 0.045 12.9 0.0 1.4 1 0 0 1 1 1 0 Tubulin like HET PF06985.11 KXH46523.1 - 9.8e-22 77.9 0.7 2e-21 76.9 0.7 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Promethin PF16015.5 KXH46524.1 - 5e-33 113.2 14.6 7.2e-33 112.7 14.6 1.2 1 0 0 1 1 1 1 Promethin Wzy_C PF04932.15 KXH46524.1 - 0.43 10.2 5.1 0.89 9.2 5.1 1.5 1 0 0 1 1 1 0 O-Antigen ligase Fungal_trans_2 PF11951.8 KXH46525.1 - 3.6e-10 39.2 0.3 3.6e-10 39.2 0.3 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH46525.1 - 1.1e-07 31.9 12.4 1.8e-07 31.1 12.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ysc84 PF04366.12 KXH46526.1 - 2.8e-44 150.0 0.1 4.5e-44 149.3 0.1 1.4 1 0 0 1 1 1 1 Las17-binding protein actin regulator AAA PF00004.29 KXH46527.1 - 5.8e-41 140.0 0.0 1e-40 139.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KXH46527.1 - 1.1e-11 44.5 0.2 2.4e-11 43.4 0.2 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 KXH46527.1 - 5.5e-11 42.1 0.4 1e-10 41.2 0.4 1.4 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 KXH46527.1 - 4.7e-06 26.8 0.0 9.5e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KXH46527.1 - 8.7e-06 26.1 0.1 0.0065 16.7 0.1 2.5 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 KXH46527.1 - 1.5e-05 24.3 0.0 2.6e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 KXH46527.1 - 0.00019 21.5 0.1 0.00066 19.7 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KXH46527.1 - 0.0004 20.8 0.1 0.0073 16.7 0.1 2.2 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 KXH46527.1 - 0.00048 19.9 0.0 0.00093 19.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Prot_ATP_OB_N PF17758.1 KXH46527.1 - 0.00099 18.7 0.3 0.0069 16.0 0.0 2.4 2 0 0 2 2 2 1 Proteasomal ATPase OB N-terminal domain AAA_18 PF13238.6 KXH46527.1 - 0.0025 18.3 0.0 0.0053 17.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KXH46527.1 - 0.0036 17.6 0.2 0.0094 16.2 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_33 PF13671.6 KXH46527.1 - 0.0086 16.2 0.1 0.029 14.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.11 KXH46527.1 - 0.018 14.9 0.0 0.034 14.0 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 KXH46527.1 - 0.018 14.8 0.0 0.038 13.7 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein PhoH PF02562.16 KXH46527.1 - 0.019 14.5 1.5 0.51 9.8 0.1 2.2 2 0 0 2 2 2 0 PhoH-like protein TIP49 PF06068.13 KXH46527.1 - 0.024 13.9 0.0 0.055 12.7 0.0 1.5 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_14 PF13173.6 KXH46527.1 - 0.03 14.4 0.0 0.058 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KXH46527.1 - 0.055 13.9 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.21 KXH46527.1 - 0.061 12.7 0.1 0.12 11.8 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.12 KXH46527.1 - 0.068 13.1 0.1 0.62 10.0 0.1 2.3 1 1 1 2 2 2 0 NACHT domain ATPase PF06745.13 KXH46527.1 - 0.079 12.3 0.0 0.49 9.7 0.0 2.0 2 0 0 2 2 2 0 KaiC Zeta_toxin PF06414.12 KXH46527.1 - 0.095 12.0 0.1 0.19 11.0 0.1 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_25 PF13481.6 KXH46527.1 - 0.099 12.2 1.1 0.58 9.7 0.4 2.3 1 1 0 2 2 2 0 AAA domain DUF2075 PF09848.9 KXH46527.1 - 0.19 10.9 0.0 0.27 10.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_24 PF13479.6 KXH46527.1 - 0.24 11.1 1.7 0.33 10.6 0.3 2.0 2 1 0 2 2 2 0 AAA domain UQ_con PF00179.26 KXH46528.1 - 1.4e-40 138.2 0.0 1.9e-40 137.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.10 KXH46528.1 - 1.9e-05 24.4 0.1 1.9e-05 24.4 0.1 1.9 2 0 0 2 2 2 1 Fungal ubiquitin-associated domain Prok-E2_B PF14461.6 KXH46528.1 - 0.0048 16.6 0.0 0.0086 15.8 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic E2 family B DUF1421 PF07223.11 KXH46528.1 - 0.08 12.8 0.1 0.15 11.9 0.1 1.4 1 0 0 1 1 1 0 UBA-like domain (DUF1421) CoA_binding PF02629.19 KXH46529.1 - 8.2e-29 100.1 2.4 1.5e-28 99.3 0.6 2.1 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 KXH46529.1 - 7.2e-23 81.1 0.2 1.2e-22 80.3 0.2 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 KXH46529.1 - 1.1e-09 38.2 0.0 1.9e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 KXH46529.1 - 1.5e-05 25.4 0.0 7.1e-05 23.3 0.0 2.1 2 0 0 2 2 2 1 CoA binding domain GFO_IDH_MocA PF01408.22 KXH46529.1 - 0.047 14.5 0.1 0.15 12.9 0.0 1.9 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold Pept_tRNA_hydro PF01195.19 KXH46530.1 - 1.8e-25 89.9 0.0 2.1e-25 89.7 0.0 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase BAR PF03114.18 KXH46531.1 - 2.3e-67 227.1 5.1 3.3e-67 226.6 5.1 1.2 1 0 0 1 1 1 1 BAR domain CP12 PF02672.15 KXH46531.1 - 0.0042 17.8 2.3 0.0085 16.8 0.0 2.6 3 1 0 3 3 3 1 CP12 domain FliD_N PF02465.18 KXH46531.1 - 8 7.2 7.4 5.8 7.7 2.4 2.6 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DCP1 PF06058.13 KXH46532.1 - 9.2e-32 109.4 0.0 1.3e-31 108.9 0.0 1.1 1 0 0 1 1 1 1 Dcp1-like decapping family Exo_endo_phos PF03372.23 KXH46533.1 - 6.2e-07 29.2 0.0 1.2e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF1835 PF08874.10 KXH46533.1 - 0.18 12.0 0.2 0.39 10.9 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1835) RhoGAP PF00620.27 KXH46533.1 - 0.24 11.2 0.3 0.56 10.0 0.0 1.7 2 0 0 2 2 2 0 RhoGAP domain Tannase PF07519.11 KXH46534.1 - 1.1e-82 278.4 0.0 1.4e-82 278.1 0.0 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Methyltransf_23 PF13489.6 KXH46535.1 - 1.9e-20 73.4 0.0 3.8e-20 72.4 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH46535.1 - 2e-08 34.8 0.0 5.8e-08 33.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH46535.1 - 1e-07 31.9 0.0 1.7e-06 27.9 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH46535.1 - 8.7e-06 26.3 0.0 1.6e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH46535.1 - 4.7e-05 24.1 0.0 0.00039 21.1 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXH46535.1 - 0.00089 18.8 0.0 0.0015 18.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.18 KXH46535.1 - 0.011 15.1 0.0 0.018 14.3 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain FtsJ PF01728.19 KXH46535.1 - 0.043 13.9 0.0 0.13 12.4 0.0 1.8 2 0 0 2 2 2 0 FtsJ-like methyltransferase PrmA PF06325.13 KXH46535.1 - 0.059 12.7 0.0 0.095 12.1 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.9 KXH46535.1 - 0.16 11.7 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_4 PF02390.17 KXH46535.1 - 0.3 10.5 0.6 0.63 9.5 0.0 1.8 2 0 0 2 2 2 0 Putative methyltransferase F-box-like PF12937.7 KXH46536.1 - 0.00013 21.7 0.0 0.00063 19.6 0.0 2.3 2 1 0 2 2 2 1 F-box-like F-box-like PF12937.7 KXH46537.1 - 0.0003 20.6 0.2 0.0012 18.7 0.2 2.2 1 0 0 1 1 1 1 F-box-like CrtC PF07143.11 KXH46538.1 - 4.8e-06 27.3 0.5 4.7e-05 24.1 0.5 2.2 1 1 0 1 1 1 1 CrtC N-terminal lipocalin domain A_deaminase PF00962.22 KXH46539.1 - 3.8e-18 65.9 0.2 9.6e-18 64.6 0.0 1.7 2 0 0 2 2 2 1 Adenosine/AMP deaminase RAI16-like PF10257.9 KXH46541.1 - 5.1e-72 242.7 3.5 8.8e-72 241.9 3.5 1.4 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein Katanin_con80 PF13925.6 KXH46541.1 - 0.14 12.2 1.0 0.81 9.7 0.1 2.5 3 0 0 3 3 3 0 con80 domain of Katanin TPP_enzyme_N PF02776.18 KXH46541.1 - 0.15 11.7 0.1 0.57 9.8 0.0 2.1 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain VSP PF03302.13 KXH46545.1 - 0.013 14.4 0.1 0.017 14.0 0.1 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein Podoplanin PF05808.11 KXH46545.1 - 0.046 13.8 0.0 0.075 13.1 0.0 1.3 1 0 0 1 1 1 0 Podoplanin Fungal_trans_2 PF11951.8 KXH46546.1 - 1e-08 34.4 1.3 2.6e-08 33.1 1.3 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH46546.1 - 2.5e-07 30.7 8.9 6.7e-07 29.3 8.9 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain OPT PF03169.15 KXH46547.1 - 9.8e-174 579.4 48.1 1.1e-173 579.2 48.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF3093 PF11292.8 KXH46547.1 - 7.2 6.9 9.5 4.7 7.5 5.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3093) Amidohydro_3 PF07969.11 KXH46548.1 - 1.1e-15 58.1 0.5 3.8e-09 36.5 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_1 PF01979.20 KXH46548.1 - 5.3e-12 45.7 0.1 7.9e-10 38.6 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family F-box-like PF12937.7 KXH46549.1 - 0.00024 20.9 0.6 0.00081 19.2 0.1 2.3 2 0 0 2 2 2 1 F-box-like Pex14_N PF04695.13 KXH46551.1 - 0.015 16.0 10.3 0.015 16.0 10.3 2.1 1 1 1 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PBP1_TM PF14812.6 KXH46551.1 - 0.084 13.3 8.7 0.14 12.5 8.7 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FAM176 PF14851.6 KXH46551.1 - 1.3 8.6 5.5 2.1 8.0 5.5 1.2 1 0 0 1 1 1 0 FAM176 family CPSF100_C PF13299.6 KXH46551.1 - 1.4 9.1 4.5 2.3 8.4 4.5 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal GREB1 PF15782.5 KXH46551.1 - 3.9 4.5 7.9 4.7 4.2 7.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer CDC45 PF02724.14 KXH46551.1 - 7.8 4.7 6.3 10 4.3 6.3 1.1 1 0 0 1 1 1 0 CDC45-like protein NAD_binding_2 PF03446.15 KXH46553.1 - 7.1e-25 88.0 0.0 1.1e-24 87.3 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KXH46553.1 - 2.4e-09 37.5 0.1 3.7e-09 36.9 0.1 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 KXH46553.1 - 0.0021 18.6 0.0 0.0065 17.0 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 KXH46553.1 - 0.014 15.4 0.0 0.025 14.6 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 KXH46554.1 - 1.5e-20 73.8 0.1 2.8e-13 49.8 0.0 2.5 2 1 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 KXH46554.1 - 4.4e-07 29.4 0.0 5.2e-05 22.6 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXH46554.1 - 2.5e-05 23.5 0.4 4e-05 22.9 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KXH46554.1 - 0.00012 22.2 0.3 0.0003 21.0 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXH46554.1 - 0.00045 19.9 1.2 0.00088 18.9 1.2 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KXH46554.1 - 0.0045 16.3 0.0 0.012 14.9 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXH46554.1 - 0.0051 15.6 0.4 0.013 14.2 0.5 1.6 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 KXH46554.1 - 0.0071 15.5 0.4 0.011 14.9 0.4 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 KXH46554.1 - 0.0086 15.5 1.1 0.013 14.9 1.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KXH46554.1 - 0.011 14.6 0.0 3.3 6.4 0.0 2.3 2 0 0 2 2 2 0 Tryptophan halogenase AlaDh_PNT_C PF01262.21 KXH46554.1 - 0.016 14.5 0.7 0.03 13.6 0.7 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 KXH46554.1 - 0.02 14.1 1.1 0.022 14.0 0.2 1.5 2 0 0 2 2 2 0 Thi4 family Pyr_redox PF00070.27 KXH46554.1 - 0.023 15.2 0.9 0.054 14.1 0.9 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 KXH46554.1 - 0.038 13.0 0.0 0.06 12.4 0.0 1.4 1 0 0 1 1 1 0 Squalene epoxidase Rossmann-like PF10727.9 KXH46554.1 - 0.13 12.1 0.2 0.3 11.0 0.2 1.6 1 0 0 1 1 1 0 Rossmann-like domain Lycopene_cycl PF05834.12 KXH46554.1 - 0.15 11.1 0.5 2.1 7.3 0.4 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein PC_rep PF01851.22 KXH46554.1 - 0.15 12.5 0.0 2.2 8.9 0.0 2.7 2 1 0 2 2 2 0 Proteasome/cyclosome repeat Amino_oxidase PF01593.24 KXH46554.1 - 0.2 10.9 0.1 3.1 7.0 0.1 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase FAD_binding_1 PF00667.20 KXH46555.1 - 3e-40 138.2 0.0 5.1e-40 137.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KXH46555.1 - 3.2e-26 92.2 0.5 1.4e-25 90.2 0.1 2.1 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.21 KXH46555.1 - 5.2e-19 68.9 0.0 2.1e-18 67.0 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain p450 PF00067.22 KXH46556.1 - 3.5e-68 230.5 0.0 4.5e-68 230.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3944 PF13099.6 KXH46556.1 - 0.16 11.9 0.0 25 4.8 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3944) Sugar_tr PF00083.24 KXH46557.1 - 5.3e-109 365.1 18.4 6.2e-109 364.9 18.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH46557.1 - 3.5e-28 98.5 55.9 1.6e-17 63.5 27.0 2.7 1 1 2 3 3 3 3 Major Facilitator Superfamily TRI12 PF06609.13 KXH46557.1 - 1.6e-05 23.5 2.6 1.6e-05 23.5 2.6 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) UNC-93 PF05978.16 KXH46557.1 - 5e-05 23.1 3.0 5e-05 23.1 3.0 2.7 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 PTR2 PF00854.21 KXH46557.1 - 0.0031 16.4 1.9 0.22 10.3 1.2 2.3 2 0 0 2 2 2 2 POT family Fungal_trans_2 PF11951.8 KXH46558.1 - 4.7e-06 25.7 0.3 5.8e-06 25.4 0.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Sugar_tr PF00083.24 KXH46559.1 - 2.5e-57 194.8 24.6 2.9e-57 194.5 24.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH46559.1 - 2.7e-16 59.4 38.7 2.7e-16 59.4 38.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Nuc_H_symport PF03825.16 KXH46559.1 - 0.00054 19.1 1.0 0.00054 19.1 1.0 2.3 2 0 0 2 2 2 1 Nucleoside H+ symporter DUF4387 PF14330.6 KXH46560.1 - 2e-33 115.0 0.0 4.2e-33 114.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4387) AtuA PF07287.11 KXH46560.1 - 5.9e-11 41.7 0.0 9.6e-11 41.0 0.0 1.4 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA Glyco_hydro_43 PF04616.14 KXH46561.1 - 4.4e-32 111.5 0.1 5.5e-32 111.2 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 p450 PF00067.22 KXH46562.1 - 0.0042 15.9 0.0 0.069 11.9 0.0 2.2 2 1 0 2 2 2 2 Cytochrome P450 Aa_trans PF01490.18 KXH46563.1 - 8.6e-29 100.5 34.0 1.6e-28 99.5 34.0 1.4 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein SHR3_chaperone PF08229.11 KXH46563.1 - 0.035 13.1 4.7 1.9 7.4 0.1 3.3 3 1 0 3 3 3 0 ER membrane protein SH3 Abhydrolase_9_N PF15420.6 KXH46563.1 - 1.5 8.8 14.1 2.4 8.1 1.1 2.4 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus MUG113 PF13455.6 KXH46564.1 - 1.2e-21 77.1 0.0 2.4e-21 76.2 0.0 1.5 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 T5orf172 PF10544.9 KXH46564.1 - 9.7e-21 74.2 0.0 3e-20 72.7 0.0 1.8 1 0 0 1 1 1 1 T5orf172 domain FA_hydroxylase PF04116.13 KXH46565.1 - 5.3e-26 91.5 17.8 5.3e-26 91.5 17.8 1.9 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily ABM PF03992.16 KXH46566.1 - 0.017 15.3 2.0 0.076 13.1 0.0 2.8 3 1 0 3 3 3 0 Antibiotic biosynthesis monooxygenase DUF1330 PF07045.11 KXH46566.1 - 0.043 14.2 0.0 0.75 10.2 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1330) TauD PF02668.16 KXH46567.1 - 6.7e-30 104.8 0.8 9.6e-30 104.3 0.8 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family FMO-like PF00743.19 KXH46568.1 - 1.4e-50 172.2 0.0 2.3e-48 164.9 0.0 2.3 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KXH46568.1 - 1.2e-17 64.1 0.0 1.2e-13 51.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXH46568.1 - 2.2e-11 43.6 0.0 1.1e-09 37.9 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXH46568.1 - 1.7e-08 34.6 0.0 4.3e-08 33.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KXH46568.1 - 2.2e-07 30.4 0.3 3.2e-06 26.5 0.0 2.8 4 0 0 4 4 4 1 L-lysine 6-monooxygenase (NADPH-requiring) Shikimate_DH PF01488.20 KXH46568.1 - 0.00074 19.6 0.0 0.25 11.4 0.0 2.5 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.6 KXH46568.1 - 0.0018 18.3 0.2 0.78 9.7 0.1 3.3 2 1 0 2 2 2 1 FAD-NAD(P)-binding 2-Hacid_dh_C PF02826.19 KXH46568.1 - 0.0062 15.9 0.0 0.38 10.1 0.0 2.4 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 KXH46568.1 - 0.056 13.9 0.0 22 5.6 0.0 2.8 2 1 0 2 2 2 0 Putative NAD(P)-binding Pyr_redox PF00070.27 KXH46568.1 - 0.12 13.0 0.0 1 9.9 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase M20_dimer PF07687.14 KXH46569.1 - 4.3e-19 68.4 0.0 7.3e-19 67.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 KXH46569.1 - 1.1e-17 64.5 0.0 6.3e-17 62.0 0.0 1.9 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.17 KXH46569.1 - 5.5e-06 26.2 0.0 8.4e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Sod_Fe_C PF02777.18 KXH46573.1 - 1.4e-33 115.1 0.6 2.1e-33 114.5 0.1 1.5 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 KXH46573.1 - 4.5e-30 104.0 4.5 4.5e-30 104.0 4.5 2.1 2 1 1 3 3 3 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Peptidase_M43 PF05572.13 KXH46575.1 - 1.1e-05 25.4 0.1 2.5e-05 24.2 0.1 1.6 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 KXH46575.1 - 0.039 14.1 0.2 0.1 12.8 0.2 1.7 1 0 0 1 1 1 0 Metallo-peptidase family M12 CFEM PF05730.11 KXH46576.1 - 7.4e-10 38.8 11.5 1.8e-09 37.6 11.5 1.6 1 0 0 1 1 1 1 CFEM domain Zn_clus PF00172.18 KXH46582.1 - 1.8e-07 31.2 10.0 3.4e-07 30.3 10.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KXH46582.1 - 3.7e-07 29.3 0.0 5.3e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_cc PF11790.8 KXH46583.1 - 3.1e-55 187.3 1.5 4e-55 187.0 1.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core NUDE_C PF04880.13 KXH46583.1 - 0.51 10.8 8.0 0.83 10.1 8.0 1.3 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region Nucleo_P87 PF07267.11 KXH46583.1 - 2.7 6.8 4.5 3.6 6.3 4.5 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 zf-RING_2 PF13639.6 KXH46585.1 - 9.3e-13 48.3 4.3 1.5e-12 47.7 4.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KXH46585.1 - 1.4e-10 40.7 1.5 2.7e-10 39.8 1.5 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KXH46585.1 - 5.1e-07 29.4 4.1 8e-07 28.8 4.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXH46585.1 - 1.1e-06 28.5 3.2 1.7e-06 27.8 3.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KXH46585.1 - 3.9e-06 27.0 5.3 9.9e-06 25.8 5.3 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 KXH46585.1 - 1.5e-05 24.7 3.5 2.7e-05 23.9 3.5 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KXH46585.1 - 4.6e-05 23.3 1.9 7.6e-05 22.6 1.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KXH46585.1 - 0.0027 17.5 2.1 0.0045 16.8 2.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KXH46585.1 - 0.0035 17.3 1.1 0.0067 16.4 1.1 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 KXH46585.1 - 0.0057 16.6 5.1 0.012 15.7 5.1 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING-like PF08746.11 KXH46585.1 - 0.049 14.0 2.3 0.078 13.3 2.3 1.3 1 0 0 1 1 1 0 RING-like domain zf-RING_4 PF14570.6 KXH46585.1 - 0.068 13.0 2.5 0.12 12.2 2.5 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.6 KXH46585.1 - 0.32 10.9 1.8 0.61 10.0 1.8 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein PHD PF00628.29 KXH46585.1 - 0.44 10.5 2.6 0.84 9.6 2.6 1.5 1 0 0 1 1 1 0 PHD-finger FANCL_C PF11793.8 KXH46585.1 - 2.2 8.5 4.0 13 6.0 4.0 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain Ubiquitin_2 PF14560.6 KXH46586.1 - 9.5e-22 77.3 0.0 1.7e-21 76.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain CAP_GLY PF01302.25 KXH46586.1 - 1.6e-21 76.0 1.1 2.5e-21 75.5 1.1 1.3 1 0 0 1 1 1 1 CAP-Gly domain ubiquitin PF00240.23 KXH46586.1 - 0.003 17.3 0.4 0.0059 16.3 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin family T6_Ig_like PF18002.1 KXH46586.1 - 0.12 12.2 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 T6 antigen Ig like domain Myb_DNA-binding PF00249.31 KXH46587.1 - 1.3e-14 54.1 2.2 4.6e-11 42.7 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KXH46587.1 - 1e-05 25.7 4.1 0.0047 17.1 0.1 2.8 3 0 0 3 3 3 2 Myb-like DNA-binding domain Methyltransf_11 PF08241.12 KXH46588.1 - 6.7e-07 29.9 0.0 5e-05 23.9 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH46588.1 - 6.5e-06 26.8 0.0 0.008 16.9 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 KXH46588.1 - 0.00015 21.7 0.0 0.00038 20.3 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH46588.1 - 0.0091 16.7 0.0 0.044 14.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH46588.1 - 0.029 14.2 0.0 0.85 9.4 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain CCDC53 PF10152.9 KXH46588.1 - 5.9 7.3 10.7 8.5 6.8 0.1 3.1 3 0 0 3 3 3 0 Subunit CCDC53 of WASH complex DUF1631 PF07793.11 KXH46588.1 - 6.5 5.0 9.7 0.17 10.3 1.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1631) GFO_IDH_MocA PF01408.22 KXH46590.1 - 3e-16 60.3 0.2 4.9e-16 59.6 0.2 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold OpuAC PF04069.12 KXH46590.1 - 0.0097 15.5 0.1 4.6 6.7 0.0 2.2 2 0 0 2 2 2 2 Substrate binding domain of ABC-type glycine betaine transport system NAD_binding_3 PF03447.16 KXH46590.1 - 0.16 12.6 0.1 0.28 11.8 0.1 1.3 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Aldo_ket_red PF00248.21 KXH46591.1 - 3.9e-15 55.8 0.0 2.8e-07 30.1 0.0 2.1 2 0 0 2 2 2 2 Aldo/keto reductase family PNRC PF15365.6 KXH46591.1 - 0.3 11.0 8.9 0.37 10.7 1.7 2.9 2 0 0 2 2 2 0 Proline-rich nuclear receptor coactivator motif SNF2_N PF00176.23 KXH46595.1 - 2.2e-63 214.1 0.5 3.8e-63 213.3 0.1 1.5 2 0 0 2 2 2 1 SNF2 family N-terminal domain ResIII PF04851.15 KXH46595.1 - 4.8e-07 29.9 0.0 8.3e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit NACHT PF05729.12 KXH46596.1 - 0.071 13.0 0.0 0.22 11.4 0.0 1.9 1 0 0 1 1 1 0 NACHT domain VTC PF09359.10 KXH46597.1 - 1.7e-91 306.4 0.4 3.9e-91 305.3 0.4 1.6 1 0 0 1 1 1 1 VTC domain DUF202 PF02656.15 KXH46597.1 - 3.3e-12 46.7 1.5 3.3e-12 46.7 1.5 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF202) SPX PF03105.19 KXH46597.1 - 1e-07 32.3 27.8 0.00022 21.3 1.1 4.2 2 1 2 4 4 4 3 SPX domain DUF3295 PF11702.8 KXH46597.1 - 0.039 13.3 5.6 0.069 12.5 5.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) FGGY_C PF02782.16 KXH46598.1 - 6.8e-47 159.8 0.4 1.1e-46 159.1 0.4 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 KXH46598.1 - 1.9e-23 83.3 0.4 4.7e-22 78.8 0.4 2.7 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.20 KXH46598.1 - 0.089 12.3 0.1 0.58 9.6 0.0 2.0 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family CFIA_Pcf11 PF11526.8 KXH46599.1 - 3.2e-07 30.7 1.4 1.1e-06 29.0 1.4 1.9 1 1 0 1 1 1 1 Subunit of cleavage factor IA Pcf11 CTD_bind PF04818.13 KXH46599.1 - 5.1e-06 27.2 0.1 3.6e-05 24.5 0.0 2.5 3 0 0 3 3 3 1 RNA polymerase II-binding domain. VHS PF00790.19 KXH46599.1 - 0.00063 19.6 0.0 0.0021 17.9 0.0 1.8 2 0 0 2 2 2 1 VHS domain zf-C2H2_4 PF13894.6 KXH46599.1 - 0.036 14.9 4.0 1.9 9.5 0.4 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2HC_2 PF13913.6 KXH46599.1 - 3.1 7.8 6.4 5.3 7.1 1.0 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf_UBZ PF18439.1 KXH46599.1 - 3.5 7.3 8.0 1.1 8.8 2.5 2.7 2 1 0 2 2 2 0 Ubiquitin-Binding Zinc Finger MoeA_N PF03453.17 KXH46600.1 - 0.21 11.3 0.0 0.31 10.8 0.0 1.2 1 0 0 1 1 1 0 MoeA N-terminal region (domain I and II) Ribosomal_L15e PF00827.17 KXH46601.1 - 4.7e-89 297.2 10.5 5.7e-89 296.9 10.5 1.0 1 0 0 1 1 1 1 Ribosomal L15 PSP1 PF04468.12 KXH46602.1 - 8.9e-28 96.4 1.3 8.9e-28 96.4 1.3 1.9 2 0 0 2 2 2 1 PSP1 C-terminal conserved region Suf PF05843.14 KXH46602.1 - 2.9 7.8 14.2 2.5 8.0 3.5 2.8 3 0 0 3 3 3 0 Suppressor of forked protein (Suf) Nfu_N PF08712.11 KXH46603.1 - 3.1e-29 100.8 0.4 1.3e-28 98.9 0.0 2.2 3 0 0 3 3 3 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.17 KXH46603.1 - 1.7e-27 95.4 0.1 2.7e-27 94.7 0.1 1.3 1 0 0 1 1 1 1 NifU-like domain YojJ PF10372.9 KXH46603.1 - 0.26 11.4 0.9 0.61 10.2 0.5 1.8 2 0 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus Adaptin_N PF01602.20 KXH46604.1 - 8e-141 470.2 5.9 9.6e-141 469.9 5.9 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 KXH46604.1 - 1.7e-15 57.3 0.0 5.8e-15 55.6 0.0 1.9 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 KXH46604.1 - 9.6e-10 38.7 4.8 3.5e-06 27.2 0.1 3.7 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 DUF3730 PF12530.8 KXH46604.1 - 1.9e-06 27.7 0.1 0.003 17.2 0.1 2.7 1 1 1 2 2 2 2 Protein of unknown function (DUF3730) HEAT_2 PF13646.6 KXH46604.1 - 0.00036 20.9 2.5 2.1 8.8 0.0 4.1 3 1 0 4 4 4 2 HEAT repeats NAD_binding_6 PF08030.12 KXH46604.1 - 0.00098 19.3 0.3 0.16 12.1 0.1 3.3 2 1 0 2 2 2 1 Ferric reductase NAD binding domain HEAT PF02985.22 KXH46604.1 - 0.0095 16.1 1.4 6.7 7.3 0.1 4.2 3 0 0 3 3 3 1 HEAT repeat NAD_binding_1 PF00175.21 KXH46604.1 - 0.028 15.1 0.3 14 6.4 0.1 2.6 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain Ndufs5 PF10200.9 KXH46606.1 - 0.00012 22.3 0.1 0.00014 22.1 0.1 1.1 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa DUF3128 PF11326.8 KXH46606.1 - 0.0062 16.9 1.4 0.016 15.5 1.3 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3128) COX6B PF02297.17 KXH46606.1 - 0.025 14.8 0.7 0.038 14.2 0.7 1.3 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb Sec39 PF08314.11 KXH46607.1 - 7e-282 937.4 0.0 8e-282 937.2 0.0 1.0 1 0 0 1 1 1 1 Secretory pathway protein Sec39 RRM_1 PF00076.22 KXH46608.1 - 7.7e-21 73.7 0.0 1.1e-20 73.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KXH46608.1 - 3.4e-05 23.4 0.0 5.1e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1793 PF08760.11 KXH46609.1 - 5.9e-75 251.3 0.9 5.9e-75 251.3 0.9 2.1 3 0 0 3 3 3 1 Domain of unknown function (DUF1793) DUF4965 PF16335.5 KXH46609.1 - 1.6e-67 226.5 0.5 1.9e-52 177.4 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4965) DUF5127 PF17168.4 KXH46609.1 - 1.3e-41 142.8 1.4 2.7e-41 141.8 1.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF4964 PF16334.5 KXH46609.1 - 0.001 18.6 0.1 0.0024 17.4 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4964) Bac_rhamnosid6H PF17389.2 KXH46609.1 - 0.009 15.3 0.6 3 7.0 0.0 2.4 2 0 0 2 2 2 2 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain adh_short_C2 PF13561.6 KXH46610.1 - 1.4e-60 204.8 1.0 1.6e-60 204.5 1.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXH46610.1 - 2.9e-46 157.4 0.8 3.3e-46 157.2 0.8 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXH46610.1 - 7.3e-12 45.6 0.4 9.8e-12 45.1 0.4 1.2 1 0 0 1 1 1 1 KR domain ZapC PF07126.12 KXH46610.1 - 0.043 13.4 0.0 0.075 12.6 0.0 1.3 1 0 0 1 1 1 0 Cell-division protein ZapC 3HCDH_N PF02737.18 KXH46610.1 - 0.044 13.7 0.1 0.066 13.1 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_25 PF13649.6 KXH46610.1 - 0.056 14.2 0.0 0.13 13.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain ADH_zinc_N PF00107.26 KXH46610.1 - 0.1 12.6 1.1 0.97 9.4 0.9 2.5 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Acetyltransf_1 PF00583.25 KXH46611.1 - 2.2e-13 50.4 0.0 3e-13 50.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXH46611.1 - 2.5e-10 40.4 0.0 3.8e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXH46611.1 - 4.6e-09 36.6 0.0 6.5e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXH46611.1 - 4.9e-06 26.4 0.0 8.1e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 KXH46611.1 - 0.0026 17.9 0.0 0.0038 17.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KXH46611.1 - 0.003 17.7 0.1 0.0062 16.7 0.1 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain STAG PF08514.11 KXH46612.1 - 0.04 13.8 0.2 0.066 13.1 0.2 1.3 1 0 0 1 1 1 0 STAG domain ATG16 PF08614.11 KXH46612.1 - 0.059 13.6 2.1 0.11 12.6 2.1 1.4 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Zw10 PF06248.13 KXH46612.1 - 0.079 11.5 0.1 0.1 11.1 0.1 1.1 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 MarR_2 PF12802.7 KXH46612.1 - 0.11 12.4 0.1 0.27 11.1 0.1 1.7 1 0 0 1 1 1 0 MarR family VPS28 PF03997.12 KXH46612.1 - 0.59 9.8 2.2 1.2 8.7 0.6 2.0 1 1 1 2 2 2 0 VPS28 protein PAS_9 PF13426.7 KXH46613.1 - 2.6e-13 50.1 0.1 1.4e-12 47.7 0.0 2.3 3 0 0 3 3 3 1 PAS domain PAS PF00989.25 KXH46613.1 - 0.011 15.7 0.0 0.12 12.4 0.0 2.4 2 0 0 2 2 2 0 PAS fold peroxidase PF00141.23 KXH46616.1 - 1.3e-22 80.7 1.1 2.1e-22 80.0 1.1 1.3 1 0 0 1 1 1 1 Peroxidase PSI_PSAK PF01241.18 KXH46616.1 - 0.072 13.1 0.0 0.22 11.6 0.0 1.8 1 0 0 1 1 1 0 Photosystem I psaG / psaK DUF5337 PF17272.2 KXH46616.1 - 0.13 12.1 0.3 0.27 11.1 0.3 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5337) GMC_oxred_C PF05199.13 KXH46617.1 - 4.5e-10 40.2 0.1 9.4e-10 39.2 0.1 1.6 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_4 PF01565.23 KXH46618.1 - 5.5e-14 52.1 0.0 1e-13 51.2 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Ribonuclease_T2 PF00445.18 KXH46618.1 - 6.6e-12 46.0 0.0 2.3e-11 44.3 0.0 1.9 1 0 0 1 1 1 1 Ribonuclease T2 family BBE PF08031.12 KXH46618.1 - 4.4e-06 26.7 0.0 1e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like Anti-TRAP PF15777.5 KXH46618.1 - 0.022 14.7 0.0 0.087 12.8 0.0 2.0 1 0 0 1 1 1 0 Tryptophan RNA-binding attenuator protein inhibitory protein Alpha_L_fucos PF01120.17 KXH46619.1 - 3.4e-29 102.4 0.5 4.9e-29 101.9 0.5 1.1 1 0 0 1 1 1 1 Alpha-L-fucosidase F5_F8_type_C PF00754.25 KXH46619.1 - 4.2e-09 36.6 0.0 4.2e-09 36.6 0.0 2.7 3 1 1 4 4 4 1 F5/8 type C domain SGL PF08450.12 KXH46620.1 - 8.7e-24 84.4 0.3 2.2e-23 83.1 0.3 1.5 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Str_synth PF03088.16 KXH46620.1 - 0.00053 20.0 0.0 0.0033 17.5 0.0 2.1 1 1 0 1 1 1 1 Strictosidine synthase Arylesterase PF01731.20 KXH46620.1 - 0.043 14.0 0.0 0.24 11.6 0.0 2.2 1 1 1 2 2 2 0 Arylesterase NHL PF01436.21 KXH46620.1 - 0.06 13.4 0.1 6 7.1 0.0 2.9 2 0 0 2 2 2 0 NHL repeat Glyco_hydro_43 PF04616.14 KXH46622.1 - 5.5e-23 81.7 0.3 1.1e-17 64.3 0.1 2.0 1 1 1 2 2 2 2 Glycosyl hydrolases family 43 CFEM PF05730.11 KXH46624.1 - 5.9e-10 39.1 8.7 1.3e-09 38.0 8.7 1.6 1 0 0 1 1 1 1 CFEM domain HNH PF01844.23 KXH46626.1 - 0.0012 19.0 1.8 0.0029 17.8 1.8 1.7 1 0 0 1 1 1 1 HNH endonuclease Hydrolase_like PF13242.6 KXH46627.1 - 4.6e-05 23.4 0.0 8e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 KXH46627.1 - 0.0009 19.6 0.0 0.0034 17.7 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KXH46627.1 - 0.0049 17.0 0.0 0.02 15.0 0.0 2.0 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase DUF2004 PF09406.10 KXH46627.1 - 0.025 14.9 0.0 0.038 14.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2004) Peripla_BP_2 PF01497.18 KXH46627.1 - 0.066 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Periplasmic binding protein ThiJ_like PF17124.5 KXH46628.1 - 9.7e-30 103.7 0.0 1.2e-29 103.4 0.0 1.1 1 0 0 1 1 1 1 ThiJ/PfpI family-like DJ-1_PfpI PF01965.24 KXH46628.1 - 1.4e-06 28.2 0.0 2.3e-06 27.5 0.0 1.5 1 1 0 1 1 1 1 DJ-1/PfpI family p450 PF00067.22 KXH46630.1 - 2.8e-45 154.9 0.0 3.8e-45 154.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Bac_globin PF01152.21 KXH46630.1 - 0.12 12.5 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial-like globin DUF3328 PF11807.8 KXH46631.1 - 0.7 9.6 4.4 0.18 11.5 0.3 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF3328) EI24 PF07264.11 KXH46631.1 - 2.2 8.5 8.7 3.4 7.9 8.7 1.2 1 0 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) AMMECR1 PF01871.17 KXH46633.1 - 2.3e-45 154.2 0.0 2.7e-45 154.0 0.0 1.2 1 1 0 1 1 1 1 AMMECR1 DUF5342 PF17277.2 KXH46633.1 - 0.033 14.5 0.0 0.074 13.4 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5342) Crystall PF00030.19 KXH46633.1 - 0.1 12.8 0.1 0.22 11.7 0.1 1.5 1 0 0 1 1 1 0 Beta/Gamma crystallin Comm PF15957.5 KXH46634.1 - 0.1 12.9 0.0 0.15 12.5 0.0 1.2 1 0 0 1 1 1 0 Commissureless SET PF00856.28 KXH46635.1 - 1.8e-08 35.0 0.0 3.5e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 SET domain Spt20 PF12090.8 KXH46636.1 - 0.8 9.3 10.2 1.1 8.8 10.2 1.1 1 0 0 1 1 1 0 Spt20 family SUIM_assoc PF16619.5 KXH46636.1 - 9.1 6.4 15.2 0.64 10.1 9.8 1.8 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Methyltransf_2 PF00891.18 KXH46637.1 - 5.7e-12 45.4 1.7 1.2e-09 37.8 0.6 2.3 1 1 1 2 2 2 2 O-methyltransferase domain DHDPS PF00701.22 KXH46639.1 - 9.2e-56 188.7 0.0 1e-55 188.5 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Fungal_trans_2 PF11951.8 KXH46640.1 - 7e-17 61.3 0.7 9.6e-17 60.9 0.7 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Aldolase_II PF00596.21 KXH46641.1 - 1.5e-49 168.5 0.1 2e-49 168.1 0.1 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Cutinase PF01083.22 KXH46642.1 - 8e-26 91.1 0.1 7.4e-24 84.7 0.0 2.1 1 1 1 2 2 2 2 Cutinase DUF2974 PF11187.8 KXH46642.1 - 0.012 15.1 0.0 0.016 14.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) VirJ PF06057.11 KXH46642.1 - 0.029 14.2 0.0 0.043 13.7 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Palm_thioest PF02089.15 KXH46642.1 - 0.062 13.1 0.0 0.086 12.7 0.0 1.1 1 0 0 1 1 1 0 Palmitoyl protein thioesterase PE-PPE PF08237.11 KXH46642.1 - 0.063 12.8 0.0 0.085 12.4 0.0 1.3 1 0 0 1 1 1 0 PE-PPE domain Cutinase PF01083.22 KXH46643.1 - 9.9e-41 139.6 0.3 1.2e-40 139.4 0.3 1.1 1 0 0 1 1 1 1 Cutinase DUF2974 PF11187.8 KXH46643.1 - 0.016 14.8 0.0 0.023 14.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) PE-PPE PF08237.11 KXH46643.1 - 0.054 13.0 0.0 0.087 12.4 0.0 1.3 1 0 0 1 1 1 0 PE-PPE domain R_equi_Vir PF05526.11 KXH46644.1 - 3.1e-11 43.5 1.4 3.3e-11 43.3 1.4 1.1 1 0 0 1 1 1 1 Rhodococcus equi virulence-associated protein eIF2A PF08662.11 KXH46647.1 - 2.5e-77 259.1 0.0 1e-76 257.1 0.0 1.9 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 KXH46647.1 - 0.0056 17.5 0.2 5.1 8.1 0.1 4.5 4 1 0 4 4 4 1 WD domain, G-beta repeat CDV3 PF15359.6 KXH46647.1 - 9.6 6.7 7.1 2.1 8.8 0.1 3.0 3 1 1 4 4 4 0 Carnitine deficiency-associated protein 3 RPAP1_C PF08620.10 KXH46649.1 - 4.6e-28 97.1 0.0 6.6e-28 96.6 0.0 1.2 1 0 0 1 1 1 1 RPAP1-like, C-terminal Pkinase PF00069.25 KXH46713.1 - 1.4e-54 185.2 1.7 4.8e-35 121.2 0.0 2.7 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXH46713.1 - 7.4e-37 127.0 0.0 4e-36 124.6 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXH46713.1 - 0.00038 19.9 0.0 0.001 18.5 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KXH46713.1 - 0.067 11.9 0.5 0.45 9.2 0.0 2.1 2 0 0 2 2 2 0 Fungal protein kinase DUF3896 PF13035.6 KXH46713.1 - 0.17 12.0 1.7 0.27 11.4 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3896) APH PF01636.23 KXH46713.1 - 0.19 11.6 0.8 0.48 10.3 0.0 2.0 3 0 0 3 3 3 0 Phosphotransferase enzyme family FAM76 PF16046.5 KXH46713.1 - 0.37 10.1 2.1 0.82 9.0 2.1 1.6 1 0 0 1 1 1 0 FAM76 protein BTB PF00651.31 KXH46714.1 - 1.7e-23 83.0 0.7 7.3e-13 48.7 0.3 3.1 3 0 0 3 3 3 2 BTB/POZ domain Ank_2 PF12796.7 KXH46714.1 - 2.8e-08 34.2 0.1 1.7e-07 31.8 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXH46714.1 - 4.8e-07 30.2 0.0 1.3e-06 28.9 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXH46714.1 - 2.6e-06 27.6 0.0 7.1e-06 26.2 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 KXH46714.1 - 6.5e-05 23.2 0.4 0.021 15.3 0.1 2.8 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 KXH46714.1 - 0.00012 22.2 0.1 0.9 10.3 0.1 3.0 2 0 0 2 2 2 2 Ankyrin repeat MoaE PF02391.17 KXH46715.1 - 5.9e-38 129.6 0.0 7.7e-38 129.3 0.0 1.2 1 0 0 1 1 1 1 MoaE protein G-patch PF01585.23 KXH46716.1 - 3.5e-12 46.0 2.8 6.9e-12 45.1 2.8 1.5 1 0 0 1 1 1 1 G-patch domain RRM_1 PF00076.22 KXH46716.1 - 2e-07 30.7 0.1 0.0095 15.7 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G-patch_2 PF12656.7 KXH46716.1 - 5e-06 26.5 2.4 1.6e-05 24.8 2.4 1.9 1 0 0 1 1 1 1 G-patch domain zf-RanBP PF00641.18 KXH46716.1 - 4.3e-05 22.7 4.3 0.0001 21.5 4.3 1.6 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others RED_N PF07808.13 KXH46716.1 - 0.0047 16.5 3.4 0.0047 16.5 3.4 2.3 2 0 0 2 2 2 1 RED-like protein N-terminal region zf-C2H2_2 PF12756.7 KXH46716.1 - 0.01 16.1 0.5 0.029 14.7 0.5 1.7 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Zf_RING PF16744.5 KXH46716.1 - 0.11 12.6 0.9 0.31 11.2 0.0 2.0 2 0 0 2 2 2 0 KIAA1045 RING finger PSRT PF07636.11 KXH46716.1 - 0.22 11.2 3.8 0.75 9.5 3.8 1.9 1 0 0 1 1 1 0 PSRT zf-C2H2_jaz PF12171.8 KXH46716.1 - 9.8 6.6 7.8 1.5 9.2 3.6 1.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Choline_kinase PF01633.20 KXH46717.1 - 1.2e-56 191.7 0.5 1.3e-55 188.3 0.0 2.2 2 0 0 2 2 2 1 Choline/ethanolamine kinase Choline_kin_N PF04428.14 KXH46717.1 - 3.4e-21 74.7 0.0 6.6e-21 73.7 0.0 1.5 1 0 0 1 1 1 1 Choline kinase N terminus APH PF01636.23 KXH46717.1 - 0.00045 20.2 0.0 0.00045 20.2 0.0 2.6 3 1 0 3 3 3 1 Phosphotransferase enzyme family Hydrolase_6 PF13344.6 KXH46718.1 - 1.8e-24 85.7 0.0 3.6e-24 84.8 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KXH46718.1 - 8.7e-18 64.2 0.1 2.1e-17 62.9 0.1 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 KXH46718.1 - 0.00022 21.6 0.6 0.49 10.6 0.0 4.1 2 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KXH46718.1 - 0.12 12.5 0.0 22 5.1 0.0 2.7 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase SCO1-SenC PF02630.14 KXH46719.1 - 8.5e-51 171.4 0.1 1.2e-50 170.9 0.1 1.2 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 KXH46719.1 - 2.3e-07 30.7 0.0 5.5e-07 29.5 0.0 1.5 1 1 1 2 2 2 1 AhpC/TSA family Redoxin PF08534.10 KXH46719.1 - 0.0024 17.6 0.0 0.065 12.9 0.0 2.2 1 1 0 1 1 1 1 Redoxin Thioredoxin_8 PF13905.6 KXH46719.1 - 0.011 16.1 0.0 0.019 15.3 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like PHD PF00628.29 KXH46720.1 - 5.9e-12 45.3 5.9 1.8e-11 43.8 5.9 1.9 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 KXH46720.1 - 0.033 13.7 1.2 0.082 12.5 1.2 1.7 1 0 0 1 1 1 0 PHD-finger PHD_4 PF16866.5 KXH46720.1 - 0.068 13.3 4.2 0.19 11.8 4.2 1.8 1 0 0 1 1 1 0 PHD-finger DUF2387 PF09526.10 KXH46720.1 - 0.32 11.2 2.5 1.6 8.9 0.2 3.0 3 0 0 3 3 3 0 Probable metal-binding protein (DUF2387) zf-RING_2 PF13639.6 KXH46720.1 - 2.1 8.8 6.4 5.2 7.5 6.4 1.7 1 0 0 1 1 1 0 Ring finger domain Asp PF00026.23 KXH46721.1 - 5.8e-63 213.2 5.7 7.9e-63 212.8 5.7 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KXH46721.1 - 7e-11 42.7 2.2 4.7e-10 40.0 2.2 2.2 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.6 KXH46721.1 - 0.00051 20.5 2.3 0.42 11.2 0.1 3.7 3 2 0 3 3 3 2 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KXH46721.1 - 0.0009 19.8 2.0 2.3 8.9 0.9 3.4 2 1 0 2 2 2 2 Aspartyl protease AIM24 PF01987.17 KXH46721.1 - 0.019 14.8 0.1 0.063 13.1 0.1 1.9 1 1 0 1 1 1 0 Mitochondrial biogenesis AIM24 SAICAR_synt PF01259.18 KXH46722.1 - 7.7e-101 336.9 0.0 9e-101 336.7 0.0 1.0 1 0 0 1 1 1 1 SAICAR synthetase Aminotran_5 PF00266.19 KXH46723.1 - 6.7e-16 58.2 0.0 9.5e-16 57.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 KXH46723.1 - 0.0027 16.9 0.0 0.0038 16.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II RHS_repeat PF05593.14 KXH46724.1 - 3.9e-20 71.9 35.5 0.0003 21.2 0.2 12.5 11 2 1 12 12 12 6 RHS Repeat VCBS PF13517.6 KXH46724.1 - 1.4e-08 35.2 6.0 0.0027 18.3 0.2 5.2 5 0 0 5 5 5 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella SpvB PF03534.13 KXH46724.1 - 3e-07 29.9 0.1 0.0055 15.9 0.0 2.4 2 0 0 2 2 2 2 Salmonella virulence plasmid 65kDa B protein TcdB_toxin_midN PF12256.8 KXH46724.1 - 1.9e-06 27.4 0.9 0.0038 16.6 0.0 4.5 3 1 1 4 4 4 1 Insecticide toxin TcdB middle/N-terminal region FG-GAP PF01839.23 KXH46724.1 - 1.4e-05 25.1 2.0 0.18 12.0 0.0 3.4 3 0 0 3 3 3 2 FG-GAP repeat DUF846 PF05832.12 KXH46724.1 - 0.021 14.9 0.0 0.038 14.0 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF846) Itfg2 PF15907.5 KXH46724.1 - 0.22 10.5 0.3 5.9 5.8 0.0 2.8 3 0 0 3 3 3 0 Integrin-alpha FG-GAP repeat-containing protein 2 DeoRC PF00455.22 KXH46725.1 - 0.15 12.0 0.0 0.26 11.2 0.0 1.3 1 0 0 1 1 1 0 DeoR C terminal sensor domain Peptidase_S9 PF00326.21 KXH46727.1 - 2e-09 37.3 0.0 3.8e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 KXH46727.1 - 3.1e-09 37.8 5.7 3.6e-09 37.5 5.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 KXH46727.1 - 7.4e-08 32.3 0.1 1.7e-07 31.1 0.1 1.5 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.8 KXH46727.1 - 1.2e-05 24.7 0.0 1.7e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KXH46727.1 - 0.0018 18.0 0.0 0.0033 17.1 0.1 1.4 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 KXH46727.1 - 0.012 15.5 0.0 0.018 14.9 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_S28 PF05577.12 KXH46727.1 - 0.23 10.2 0.0 0.28 9.9 0.0 1.1 1 0 0 1 1 1 0 Serine carboxypeptidase S28 adh_short PF00106.25 KXH46728.1 - 1.2e-34 119.5 0.2 1.7e-34 119.0 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXH46728.1 - 1.3e-22 80.6 0.1 1.8e-22 80.0 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH46728.1 - 6e-07 29.5 6.2 6.1e-06 26.3 2.1 2.8 1 1 1 2 2 2 1 KR domain Epimerase PF01370.21 KXH46728.1 - 0.00026 20.5 0.0 0.00057 19.4 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KXH46728.1 - 0.0073 15.4 0.0 0.0094 15.1 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain QRPTase_C PF01729.19 KXH46728.1 - 0.047 13.5 1.5 6 6.6 0.0 2.9 2 1 1 3 3 3 0 Quinolinate phosphoribosyl transferase, C-terminal domain PARP_reg PF02877.14 KXH46728.1 - 0.077 13.1 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Poly(ADP-ribose) polymerase, regulatory domain NAD_binding_4 PF07993.12 KXH46728.1 - 0.16 11.1 0.8 0.46 9.6 0.1 1.9 2 0 0 2 2 2 0 Male sterility protein DUF3433 PF11915.8 KXH46732.1 - 1.3e-28 99.3 21.3 9.6e-27 93.3 6.1 4.4 6 1 0 6 6 6 2 Protein of unknown function (DUF3433) DUF2457 PF10446.9 KXH46732.1 - 6.3 5.8 9.4 13 4.8 9.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Pmp3 PF01679.17 KXH46733.1 - 0.12 12.6 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Proteolipid membrane potential modulator Fasciclin PF02469.22 KXH46735.1 - 1.9e-39 134.8 0.0 3e-21 76.0 0.0 2.3 2 0 0 2 2 2 2 Fasciclin domain PPP4R2 PF09184.11 KXH46735.1 - 4.8 6.7 12.2 11 5.5 12.2 1.5 1 0 0 1 1 1 0 PPP4R2 Pal1 PF08316.11 KXH46736.1 - 1.5e-43 148.9 0.5 4.3e-43 147.4 0.5 1.9 1 0 0 1 1 1 1 Pal1 cell morphology protein adh_short PF00106.25 KXH46737.1 - 1.1e-15 57.7 0.0 1.5e-15 57.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXH46737.1 - 3.6e-09 36.5 0.0 5.1e-09 36.0 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase p450 PF00067.22 KXH46738.1 - 1.1e-45 156.3 0.0 6e-32 111.0 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 TAXi_C PF14541.6 KXH46738.1 - 0.053 13.3 0.0 0.099 12.4 0.0 1.3 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal FAD_binding_4 PF01565.23 KXH46739.1 - 4.5e-19 68.6 1.5 6.6e-19 68.0 1.5 1.2 1 0 0 1 1 1 1 FAD binding domain ALO PF04030.14 KXH46739.1 - 3.2e-13 50.1 0.9 1e-11 45.2 0.9 2.4 1 1 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD-oxidase_C PF02913.19 KXH46739.1 - 0.03 14.0 0.0 2 8.0 0.0 2.3 2 0 0 2 2 2 0 FAD linked oxidases, C-terminal domain bZIP_1 PF00170.21 KXH46821.1 - 1.6e-06 28.1 4.8 1.6e-06 28.1 4.8 1.6 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 KXH46821.1 - 2.6e-05 24.2 4.4 2.6e-05 24.2 4.4 1.7 2 0 0 2 2 2 1 Basic region leucine zipper SHE3 PF17078.5 KXH46821.1 - 0.014 15.2 1.8 0.021 14.6 1.8 1.2 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 bZIP_Maf PF03131.17 KXH46821.1 - 0.035 14.6 9.0 0.071 13.6 8.9 1.6 1 1 0 1 1 1 0 bZIP Maf transcription factor PKcGMP_CC PF16808.5 KXH46821.1 - 0.064 13.1 1.9 0.13 12.2 1.9 1.4 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase MAJIN PF15077.6 KXH46821.1 - 3.2 7.5 6.3 4.1 7.1 6.3 1.2 1 0 0 1 1 1 0 Membrane-anchored junction protein TPR_12 PF13424.6 KXH46822.1 - 4.6e-10 39.7 6.3 0.0015 18.8 0.1 3.9 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KXH46822.1 - 8.8e-07 28.6 0.4 0.015 15.3 0.0 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 KXH46822.1 - 3.7e-05 23.3 0.8 0.29 11.0 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 KXH46822.1 - 4.4e-05 23.2 0.8 2 8.6 0.0 4.8 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 KXH46822.1 - 0.00077 19.5 0.5 0.32 11.3 0.0 3.6 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 KXH46822.1 - 0.013 15.4 5.0 0.099 12.5 0.0 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 KXH46822.1 - 0.044 14.4 1.7 11 6.9 0.1 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat RPN7 PF10602.9 KXH46822.1 - 0.055 13.2 0.5 1.7 8.3 0.0 2.8 4 0 0 4 4 4 0 26S proteasome subunit RPN7 TPR_21 PF09976.9 KXH46822.1 - 0.081 12.6 0.1 0.51 10.0 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat-like domain ANAPC3 PF12895.7 KXH46822.1 - 0.085 13.1 0.2 0.51 10.6 0.0 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 KXH46822.1 - 0.095 13.4 0.2 22 5.8 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat Ndc1_Nup PF09531.10 KXH46822.1 - 0.15 10.7 0.2 4.1 6.0 0.0 2.1 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup PRIMA1 PF16101.5 KXH46822.1 - 0.17 11.9 1.7 0.44 10.6 1.7 1.7 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 TPR_11 PF13414.6 KXH46822.1 - 0.33 10.7 1.4 21 4.9 0.0 3.6 4 0 0 4 4 3 0 TPR repeat Cyt-b5 PF00173.28 KXH46823.1 - 1.1e-07 31.9 0.1 3.5e-05 23.9 0.0 2.2 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain zf-C2H2 PF00096.26 KXH46825.1 - 2e-07 31.1 46.4 0.0052 17.2 5.0 6.6 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXH46825.1 - 0.00068 20.3 47.6 0.098 13.5 3.4 7.1 7 0 0 7 7 7 3 C2H2-type zinc finger FOXP-CC PF16159.5 KXH46825.1 - 0.029 15.0 0.6 0.029 15.0 0.6 5.2 4 1 1 5 5 5 0 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 KXH46825.1 - 0.74 10.2 9.0 0.6 10.4 0.6 3.4 2 2 2 4 4 4 0 C2H2-type zinc ribbon zf-C2H2_6 PF13912.6 KXH46825.1 - 0.79 9.8 9.8 0.97 9.5 1.6 4.3 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KXH46825.1 - 1.3 9.4 27.5 0.6 10.5 3.4 5.8 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding HGTP_anticodon PF03129.20 KXH46851.1 - 4.2e-22 78.1 2.5 5e-21 74.7 0.0 3.2 3 0 0 3 3 3 1 Anticodon binding domain tRNA-synt_2b PF00587.25 KXH46851.1 - 5.5e-08 33.0 0.0 5.6e-07 29.7 0.0 2.3 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Brix PF04427.18 KXH46852.1 - 9.5e-24 84.6 0.3 1.6e-23 83.9 0.3 1.4 1 0 0 1 1 1 1 Brix domain BUD22 PF09073.10 KXH46852.1 - 2 7.7 29.6 3.1 7.1 29.6 1.1 1 0 0 1 1 1 0 BUD22 TipE PF16972.5 KXH46852.1 - 2.7 7.1 9.0 4.2 6.4 9.0 1.2 1 0 0 1 1 1 0 Na+ channel auxiliary subunit TipE Sporozoite_P67 PF05642.11 KXH46852.1 - 4 5.4 7.2 5.8 4.9 7.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen TPT PF03151.16 KXH46853.1 - 8.2e-06 25.4 16.8 2.6e-05 23.7 16.8 1.7 1 1 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KXH46853.1 - 4.7e-05 23.6 12.3 4.7e-05 23.6 12.3 2.3 2 0 0 2 2 2 1 EamA-like transporter family UPF0139 PF03669.13 KXH46853.1 - 0.021 14.7 0.2 0.07 13.0 0.2 1.9 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0139) CRPA PF05745.11 KXH46853.1 - 2.5 8.1 5.6 0.8 9.7 0.3 2.6 3 0 0 3 3 3 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) GDP_Man_Dehyd PF16363.5 KXH46855.1 - 1.3e-69 235.2 0.0 1.5e-69 235.0 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KXH46855.1 - 4e-57 193.4 0.0 5e-57 193.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KXH46855.1 - 5.6e-24 84.8 0.0 8.1e-23 81.0 0.0 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 KXH46855.1 - 8.7e-19 67.6 0.0 1.1e-18 67.2 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KXH46855.1 - 1.2e-18 67.2 0.1 1.8e-17 63.4 0.1 2.1 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.17 KXH46855.1 - 6.5e-17 61.5 0.0 8.5e-17 61.2 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 KXH46855.1 - 1.2e-07 31.8 0.0 2.2e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 KXH46855.1 - 0.2 11.1 0.0 1.6 8.2 0.1 2.1 2 0 0 2 2 2 0 short chain dehydrogenase P_proprotein PF01483.20 KXH46861.1 - 0.013 15.5 0.4 0.021 14.8 0.4 1.3 1 0 0 1 1 1 0 Proprotein convertase P-domain Gallidermin PF02052.15 KXH46861.1 - 0.13 12.7 0.3 0.22 11.9 0.3 1.4 1 0 0 1 1 1 0 Gallidermin p450 PF00067.22 KXH46862.1 - 1.2e-44 152.8 0.0 1.3e-44 152.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 NACHT_N PF17100.5 KXH46863.1 - 4.3e-65 219.7 0.1 1.1e-64 218.4 0.1 1.7 1 0 0 1 1 1 1 N-terminal domain of NWD NACHT-NTPase WD40 PF00400.32 KXH46863.1 - 9.7e-42 140.2 14.9 1.4e-07 32.1 0.2 11.0 11 0 0 11 11 11 7 WD domain, G-beta repeat NACHT PF05729.12 KXH46863.1 - 9.2e-16 58.2 0.1 1.9e-15 57.2 0.1 1.5 1 0 0 1 1 1 1 NACHT domain ANAPC4_WD40 PF12894.7 KXH46863.1 - 4.5e-15 55.7 0.2 0.011 16.0 0.0 6.4 3 2 1 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KXH46863.1 - 2.3e-09 36.4 1.9 0.065 11.9 0.0 5.1 3 1 2 5 5 5 3 Nucleoporin Nup120/160 PD40 PF07676.12 KXH46863.1 - 7.1e-05 22.6 10.5 3.3 7.7 0.0 8.2 10 0 0 10 10 10 2 WD40-like Beta Propeller Repeat AAA_16 PF13191.6 KXH46863.1 - 0.00012 22.6 0.0 0.0005 20.5 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain Cytochrom_D1 PF02239.16 KXH46863.1 - 0.00044 18.9 0.9 1.6 7.2 0.0 3.8 3 1 1 4 4 4 2 Cytochrome D1 heme domain Nbas_N PF15492.6 KXH46863.1 - 0.0016 17.8 2.1 15 4.8 0.0 4.8 5 1 0 5 5 5 0 Neuroblastoma-amplified sequence, N terminal KAP_NTPase PF07693.14 KXH46863.1 - 0.0036 16.6 0.0 0.0088 15.3 0.0 1.6 1 0 0 1 1 1 1 KAP family P-loop domain DUF1513 PF07433.11 KXH46863.1 - 0.0042 16.2 0.1 4.1 6.4 0.0 3.9 3 2 0 3 3 3 1 Protein of unknown function (DUF1513) Ge1_WD40 PF16529.5 KXH46863.1 - 0.024 13.6 6.5 17 4.3 0.0 5.2 4 3 0 6 6 6 0 WD40 region of Ge1, enhancer of mRNA-decapping protein AAA_22 PF13401.6 KXH46863.1 - 0.042 14.1 0.8 4.4 7.6 0.0 3.3 3 0 0 3 3 3 0 AAA domain Nucleoporin_N PF08801.11 KXH46863.1 - 0.062 12.0 0.1 12 4.5 0.0 3.0 4 0 0 4 4 4 0 Nup133 N terminal like PALB2_WD40 PF16756.5 KXH46863.1 - 0.11 11.4 1.9 6.7 5.5 0.1 3.2 2 1 1 3 3 3 0 Partner and localizer of BRCA2 WD40 domain DUF5122 PF17164.4 KXH46863.1 - 0.11 12.8 0.1 1.2 9.5 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF5122) beta-propeller F-box PF00646.33 KXH46864.1 - 1.4e-06 28.0 0.0 0.00039 20.2 0.0 3.2 3 0 0 3 3 3 2 F-box domain F-box-like PF12937.7 KXH46864.1 - 0.0057 16.5 0.0 0.023 14.6 0.0 2.1 1 0 0 1 1 1 1 F-box-like MFS_1 PF07690.16 KXH46865.1 - 9.4e-40 136.6 50.0 2.3e-39 135.3 47.2 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KXH46865.1 - 2e-11 43.1 19.3 3.4e-11 42.3 19.3 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 KXH46865.1 - 0.0032 15.8 2.3 0.0032 15.8 2.3 3.0 3 1 0 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family EBP PF05241.12 KXH46866.1 - 1.1e-54 184.6 8.5 2.8e-54 183.3 8.5 1.6 1 1 0 1 1 1 1 Emopamil binding protein Asparaginase PF00710.20 KXH46867.1 - 1.1e-52 178.4 0.1 1.9e-52 177.6 0.1 1.3 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 KXH46867.1 - 9.3e-19 67.7 0.1 3.5e-18 65.9 0.0 2.0 3 0 0 3 3 3 1 Glutaminase/Asparaginase C-terminal domain Hce2 PF14856.6 KXH46868.1 - 6.4e-24 84.2 0.2 3e-07 30.7 0.2 4.1 4 0 0 4 4 4 3 Pathogen effector; putative necrosis-inducing factor Peptidase_M28 PF04389.17 KXH46869.1 - 3.6e-30 105.1 0.0 4.8e-30 104.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KXH46869.1 - 5.1e-06 26.3 0.4 3.1e-05 23.8 0.4 2.0 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 2OG-FeII_Oxy PF03171.20 KXH46872.1 - 1.3e-12 48.1 0.0 2.3e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 KXH46872.1 - 3e-09 37.7 0.0 5.7e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Amidohydro_3 PF07969.11 KXH46873.1 - 1.1e-15 58.1 0.8 2e-12 47.3 0.0 2.6 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_1 PF01979.20 KXH46873.1 - 6.8e-12 45.4 1.6 2.4e-11 43.6 0.4 2.4 2 1 0 2 2 2 1 Amidohydrolase family PHD_2 PF13831.6 KXH46873.1 - 0.13 11.8 0.5 0.29 10.7 0.5 1.5 1 0 0 1 1 1 0 PHD-finger Glyco_hydro_20 PF00728.22 KXH46874.1 - 2.4e-25 89.7 0.5 1.6e-22 80.4 0.5 2.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glyco_hydro_20b PF02838.15 KXH46874.1 - 4.6e-08 33.9 0.0 9.7e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Ferric_reduct PF01794.19 KXH46875.1 - 6.8e-21 74.7 13.5 6.8e-21 74.7 13.5 2.5 2 1 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KXH46875.1 - 2.8e-13 50.3 0.0 4.2e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KXH46875.1 - 6.7e-13 48.7 0.0 1.1e-12 48.0 0.0 1.3 1 0 0 1 1 1 1 FAD-binding domain DUF4405 PF14358.6 KXH46875.1 - 1 10.0 20.7 0.089 13.3 3.6 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF4405) Ctr PF04145.15 KXH46876.1 - 9.5e-28 97.7 0.1 1.2e-27 97.3 0.1 1.2 1 0 0 1 1 1 1 Ctr copper transporter family DUF3433 PF11915.8 KXH46877.1 - 4e-35 120.1 6.2 6.3e-19 68.2 0.3 4.0 5 0 0 5 5 5 2 Protein of unknown function (DUF3433) Pox_I5 PF04713.12 KXH46877.1 - 0.0038 17.2 0.1 0.035 14.2 0.1 2.8 1 0 0 1 1 1 1 Poxvirus protein I5 Sdh_cyt PF01127.22 KXH46877.1 - 2.8 8.0 7.4 1.4 9.0 2.9 2.8 2 0 0 2 2 2 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF2207 PF09972.9 KXH46877.1 - 5.6 5.6 0.0 5.6 5.6 0.0 4.2 3 1 1 4 4 4 0 Predicted membrane protein (DUF2207) Fasciclin PF02469.22 KXH46878.1 - 3.8e-41 140.3 0.1 2e-20 73.3 0.0 2.2 2 0 0 2 2 2 2 Fasciclin domain Cellulase PF00150.18 KXH46878.1 - 0.019 14.4 0.0 0.028 13.8 0.0 1.3 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) DUF719 PF05334.13 KXH46878.1 - 0.12 12.5 0.0 1.6 8.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF719) HAD_2 PF13419.6 KXH46878.1 - 0.15 12.1 2.6 0.26 11.4 0.7 2.2 1 1 1 2 2 2 0 Haloacid dehalogenase-like hydrolase GMC_oxred_C PF05199.13 KXH46879.1 - 4.3e-07 30.5 0.0 1.3e-06 29.0 0.0 1.8 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 KXH46879.1 - 1.9e-05 24.2 0.0 0.0026 17.2 0.0 2.6 3 0 0 3 3 3 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KXH46879.1 - 5.3e-05 22.5 0.1 8.9e-05 21.7 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KXH46879.1 - 0.00011 21.6 0.2 0.00018 20.8 0.2 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KXH46879.1 - 0.00054 19.4 0.1 0.00098 18.6 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXH46879.1 - 0.0034 17.6 0.2 0.019 15.2 0.2 2.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KXH46879.1 - 0.027 13.2 0.1 0.043 12.5 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.22 KXH46879.1 - 0.03 13.4 0.1 0.053 12.6 0.1 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox PF00070.27 KXH46879.1 - 0.032 14.8 0.0 0.1 13.2 0.0 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXH46879.1 - 0.082 12.5 0.0 0.21 11.2 0.0 1.7 1 0 0 1 1 1 0 FAD dependent oxidoreductase CC190 PF15768.5 KXH46881.1 - 0.0087 16.2 11.4 0.01 15.9 11.4 1.0 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 190 PID PF00640.23 KXH46881.1 - 0.034 14.2 0.3 0.044 13.8 0.3 1.2 1 0 0 1 1 1 0 Phosphotyrosine interaction domain (PTB/PID) Spt20 PF12090.8 KXH46881.1 - 0.5 9.9 9.1 0.7 9.5 9.1 1.2 1 0 0 1 1 1 0 Spt20 family Serglycin PF04360.12 KXH46881.1 - 0.87 9.5 8.2 1.5 8.7 8.2 1.6 1 1 0 1 1 1 0 Serglycin RR_TM4-6 PF06459.12 KXH46881.1 - 4.3 7.1 9.6 4.8 6.9 9.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 MmgE_PrpD PF03972.14 KXH46882.1 - 1.2e-120 403.1 3.2 1.5e-120 402.8 3.2 1.0 1 0 0 1 1 1 1 MmgE/PrpD family Epimerase PF01370.21 KXH46884.1 - 8.4e-16 58.2 0.0 1.4e-15 57.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXH46884.1 - 3.6e-13 49.1 0.0 6.1e-13 48.4 0.0 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KXH46884.1 - 2e-09 37.6 0.0 2.8e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KXH46884.1 - 7.2e-09 35.5 0.0 1.1e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KXH46884.1 - 7.8e-09 35.1 0.0 0.00049 19.3 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein NmrA PF05368.13 KXH46884.1 - 2.9e-06 27.0 0.1 1.2e-05 25.0 0.2 1.8 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.25 KXH46884.1 - 0.00015 21.3 0.3 0.00067 19.2 0.2 2.1 2 1 0 2 2 2 1 short chain dehydrogenase Sacchrp_dh_NADP PF03435.18 KXH46884.1 - 0.0015 18.8 0.1 0.0032 17.7 0.1 1.6 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain KR PF08659.10 KXH46884.1 - 0.0036 17.2 0.2 0.011 15.6 0.2 1.7 1 1 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.17 KXH46884.1 - 0.0062 15.7 0.0 0.0097 15.0 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KXH46884.1 - 0.0063 15.7 0.1 0.0095 15.1 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Glyco_hydro_61 PF03443.14 KXH46885.1 - 5.3e-58 196.3 0.1 6.6e-58 196.0 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Dehydratase_hem PF13816.6 KXH46887.1 - 1e-89 301.0 0.0 1.2e-89 300.8 0.0 1.0 1 0 0 1 1 1 1 Haem-containing dehydratase DUF1330 PF07045.11 KXH46887.1 - 0.064 13.6 0.0 0.17 12.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1330) adh_short PF00106.25 KXH46889.1 - 8.2e-35 120.0 0.0 1e-34 119.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXH46889.1 - 2e-24 86.5 0.0 3e-24 85.9 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH46889.1 - 2.6e-08 34.0 0.0 3.6e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KXH46889.1 - 0.00021 21.2 0.0 0.00037 20.4 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KXH46889.1 - 0.11 12.0 0.0 0.3 10.5 0.0 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Pkinase PF00069.25 KXH46890.1 - 2.2e-28 99.4 0.0 1.3e-26 93.5 0.0 2.7 1 1 0 1 1 1 1 Protein kinase domain AltA1 PF16541.5 KXH46891.1 - 7.6e-26 91.1 1.6 9.9e-26 90.8 1.6 1.1 1 0 0 1 1 1 1 Alternaria alternata allergen 1 XAP5 PF04921.14 KXH46893.1 - 3e-97 325.4 0.1 4.1e-97 324.9 0.1 1.2 1 0 0 1 1 1 1 XAP5, circadian clock regulator DUF4604 PF15377.6 KXH46893.1 - 4.1e-05 24.1 5.4 4.1e-05 24.1 5.4 2.4 1 1 1 2 2 2 1 Domain of unknown function (DUF4604) ORC6 PF05460.13 KXH46893.1 - 0.024 13.9 5.4 0.034 13.4 5.4 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Peptidase_M13_N PF05649.13 KXH46894.1 - 0.066 12.9 0.0 0.079 12.6 0.0 1.1 1 0 0 1 1 1 0 Peptidase family M13 CDC50 PF03381.15 KXH46894.1 - 0.086 12.3 0.0 0.12 11.9 0.0 1.1 1 0 0 1 1 1 0 LEM3 (ligand-effect modulator 3) family / CDC50 family Methyltransf_10 PF05971.12 KXH46895.1 - 2.4e-59 201.1 0.0 3.3e-59 200.7 0.0 1.1 1 0 0 1 1 1 1 RNA methyltransferase MTS PF05175.14 KXH46895.1 - 2.7e-05 23.8 0.0 4.4e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 KXH46895.1 - 0.00041 19.8 0.0 0.0017 17.8 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Met_10 PF02475.16 KXH46895.1 - 0.037 13.8 0.0 0.057 13.1 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_31 PF13847.6 KXH46895.1 - 0.064 13.1 0.0 0.36 10.6 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_18 PF12847.7 KXH46895.1 - 0.13 12.2 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain UPF0020 PF01170.18 KXH46895.1 - 0.13 11.9 0.0 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_25 PF13649.6 KXH46895.1 - 0.15 12.8 0.0 0.42 11.4 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain NAD_binding_10 PF13460.6 KXH46896.1 - 8.1e-16 58.4 0.0 2.1e-15 57.1 0.0 1.8 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KXH46896.1 - 2.6e-14 53.3 0.0 3.4e-14 53.0 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 KXH46896.1 - 2.8e-05 23.7 0.0 0.00013 21.5 0.0 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KXH46896.1 - 8.2e-05 22.6 0.0 0.00018 21.4 0.0 1.6 2 0 0 2 2 2 1 KR domain Sacchrp_dh_NADP PF03435.18 KXH46896.1 - 0.0011 19.3 0.0 0.0019 18.4 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain DapB_N PF01113.20 KXH46896.1 - 0.0022 18.1 0.4 0.34 11.0 0.0 2.5 3 0 0 3 3 3 1 Dihydrodipicolinate reductase, N-terminus F420_oxidored PF03807.17 KXH46896.1 - 0.0024 18.4 0.1 0.0073 16.9 0.0 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 3Beta_HSD PF01073.19 KXH46896.1 - 0.0028 16.7 0.0 0.0042 16.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Shikimate_DH PF01488.20 KXH46896.1 - 0.0036 17.4 0.0 0.0072 16.4 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Zn_clus PF00172.18 KXH46897.1 - 9.9e-05 22.4 9.8 0.00021 21.4 9.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXH46897.1 - 0.00043 19.4 0.1 0.00084 18.5 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cellulase PF00150.18 KXH46899.1 - 1.5e-16 60.7 1.4 2.1e-16 60.2 1.4 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Ank_3 PF13606.6 KXH46900.1 - 1.5e-11 43.4 0.0 0.017 15.6 0.0 4.2 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.7 KXH46900.1 - 7.9e-11 42.4 0.1 8.8e-10 39.0 0.0 2.8 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ank PF00023.30 KXH46900.1 - 6.1e-09 35.9 1.2 0.0016 18.8 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 KXH46900.1 - 7.1e-06 26.5 0.0 5.6e-05 23.6 0.0 2.6 3 0 0 3 3 3 1 Ankyrin repeats (many copies) NACHT PF05729.12 KXH46900.1 - 8.2e-06 25.8 0.1 1.7e-05 24.8 0.1 1.5 1 0 0 1 1 1 1 NACHT domain Ank_5 PF13857.6 KXH46900.1 - 2e-05 24.8 0.0 0.0019 18.5 0.0 2.6 1 1 2 3 3 3 3 Ankyrin repeats (many copies) AAA_16 PF13191.6 KXH46900.1 - 0.00099 19.5 0.3 0.01 16.3 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain Torsin PF06309.11 KXH46900.1 - 0.045 13.8 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Torsin Asp_protease_2 PF13650.6 KXH46900.1 - 0.12 13.0 0.0 14 6.4 0.0 3.3 3 0 0 3 3 3 0 Aspartyl protease DUF3364 PF11844.8 KXH46901.1 - 0.13 12.6 0.0 0.28 11.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3364) CBM49 PF09478.10 KXH46901.1 - 0.21 11.9 0.5 0.57 10.5 0.2 1.8 2 0 0 2 2 2 0 Carbohydrate binding domain CBM49 RVT_1 PF00078.27 KXH46903.1 - 1.1e-24 87.2 0.0 2.8e-24 85.9 0.0 1.7 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) GATase_4 PF13230.6 KXH46905.1 - 1.9e-08 33.6 0.1 3.8e-06 26.0 0.1 2.5 2 1 0 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.6 KXH46905.1 - 4.7e-07 30.1 0.0 8.5e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pex14_N PF04695.13 KXH46906.1 - 0.00014 22.6 1.0 0.00014 22.6 1.0 2.1 1 1 1 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region SOG2 PF10428.9 KXH46906.1 - 0.012 14.8 5.4 0.015 14.5 5.4 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein PAN_4 PF14295.6 KXH46906.1 - 0.034 14.1 1.7 0.28 11.1 1.7 2.3 1 1 0 1 1 1 0 PAN domain Zip PF02535.22 KXH46906.1 - 0.15 11.3 0.1 0.22 10.7 0.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter PAN_1 PF00024.26 KXH46906.1 - 1.3 9.0 5.5 0.18 11.8 0.7 1.9 2 0 0 2 2 2 0 PAN domain Acetyltransf_3 PF13302.7 KXH46907.1 - 4.3e-25 89.0 0.0 5.1e-25 88.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXH46907.1 - 0.0045 17.2 0.1 0.13 12.5 0.1 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 KXH46907.1 - 0.19 11.8 0.0 1.7 8.8 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Ank_2 PF12796.7 KXH46908.1 - 1.6e-28 99.1 1.1 1e-11 45.3 0.0 4.4 3 1 1 4 4 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXH46908.1 - 2.5e-18 66.2 1.0 0.0066 17.0 0.0 6.2 5 1 0 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXH46908.1 - 4.5e-15 55.5 2.9 0.0026 18.0 0.0 6.5 2 2 4 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXH46908.1 - 3e-14 51.7 3.7 0.0008 19.7 0.0 8.0 7 0 0 7 7 7 2 Ankyrin repeat Ank PF00023.30 KXH46908.1 - 1.8e-13 50.3 8.4 0.002 18.5 0.1 7.8 7 0 0 7 7 7 3 Ankyrin repeat AAA_22 PF13401.6 KXH46908.1 - 1.5e-05 25.3 0.0 0.00011 22.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KXH46908.1 - 2.3e-05 24.4 0.0 6.3e-05 23.0 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KXH46908.1 - 2.9e-05 24.5 1.6 0.00029 21.3 0.1 3.3 3 1 0 3 3 3 1 AAA ATPase domain KAP_NTPase PF07693.14 KXH46908.1 - 0.002 17.4 0.7 1.7 7.8 0.6 2.4 1 1 1 2 2 2 2 KAP family P-loop domain NACHT_N PF17100.5 KXH46908.1 - 0.0047 16.8 0.1 0.86 9.4 0.0 2.6 1 1 1 2 2 2 1 N-terminal domain of NWD NACHT-NTPase Zeta_toxin PF06414.12 KXH46908.1 - 0.0095 15.2 0.0 0.045 13.0 0.0 2.1 3 0 0 3 3 3 1 Zeta toxin AAA_18 PF13238.6 KXH46908.1 - 0.07 13.7 0.0 0.18 12.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 KXH46908.1 - 0.14 11.9 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein zf-C2H2 PF00096.26 KXH46909.1 - 2.8e-06 27.5 13.3 0.001 19.4 1.7 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXH46909.1 - 0.00032 21.3 18.2 0.0093 16.7 1.0 3.9 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 KXH46909.1 - 0.55 10.4 4.1 0.19 11.8 0.3 2.0 1 1 1 2 2 2 0 Aberrant zinc-finger zf-H2C2_2 PF13465.6 KXH46909.1 - 1.6 9.3 8.7 2.4 8.7 0.6 3.3 3 0 0 3 3 3 0 Zinc-finger double domain DUF4139 PF13598.6 KXH46910.1 - 2.2e-38 132.1 1.0 5.1e-38 130.9 1.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4139) DUF4140 PF13600.6 KXH46910.1 - 3.5e-26 91.5 0.4 3.5e-26 91.5 0.4 4.0 3 1 0 3 3 3 1 N-terminal domain of unknown function (DUF4140) UDPG_MGDP_dh_N PF03721.14 KXH46912.1 - 3.3e-50 170.3 0.0 1.8e-31 109.2 0.0 2.3 2 0 0 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.19 KXH46912.1 - 8.1e-32 109.3 0.0 1.8e-31 108.2 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.15 KXH46912.1 - 8.5e-21 74.4 0.0 6.7e-17 61.8 0.0 3.3 3 0 0 3 3 3 2 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Sacchrp_dh_NADP PF03435.18 KXH46912.1 - 0.0073 16.6 0.0 0.018 15.3 0.0 1.7 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_2 PF03446.15 KXH46912.1 - 0.019 15.1 0.0 1.2 9.3 0.0 2.6 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 KXH46912.1 - 0.1 12.5 0.0 0.34 10.8 0.0 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Glycos_transf_1 PF00534.20 KXH46913.1 - 2.7e-35 121.4 0.0 5e-35 120.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KXH46913.1 - 2.7e-29 102.3 0.0 5.2e-29 101.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KXH46913.1 - 3.8e-17 63.2 0.1 9.3e-17 61.9 0.1 1.7 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 KXH46913.1 - 2.8e-13 50.2 0.0 7e-12 45.7 0.0 2.2 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 KXH46913.1 - 2.3e-11 44.0 0.0 5.8e-11 42.6 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Fungal_trans PF04082.18 KXH46915.1 - 2e-25 89.4 0.4 2.8e-25 88.8 0.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH46915.1 - 1.2e-05 25.4 6.6 1.9e-05 24.7 6.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Phage_Coat_Gp8 PF05371.12 KXH46915.1 - 0.13 12.0 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 Phage major coat protein, Gp8 ECH_1 PF00378.20 KXH46916.1 - 9.7e-47 159.4 0.0 1.2e-46 159.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXH46916.1 - 2.5e-22 79.8 0.0 3.4e-22 79.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase 4HBT_2 PF13279.6 KXH46917.1 - 0.003 18.0 0.0 0.0084 16.6 0.0 1.8 1 1 0 1 1 1 1 Thioesterase-like superfamily p450 PF00067.22 KXH46918.1 - 6.5e-73 246.0 0.0 8.9e-73 245.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.20 KXH46918.1 - 1.1e-33 116.6 0.0 2.1e-33 115.8 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KXH46918.1 - 1.6e-24 86.7 0.0 3.4e-24 85.7 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 KXH46918.1 - 8.2e-12 45.7 0.0 2.3e-11 44.3 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KXH46918.1 - 0.054 13.8 0.0 0.2 12.1 0.0 1.9 2 0 0 2 2 2 0 Oxidoreductase FAD-binding domain Rx_N PF18052.1 KXH46918.1 - 0.097 13.0 0.2 0.27 11.5 0.2 1.8 1 0 0 1 1 1 0 Rx N-terminal domain AMP-binding PF00501.28 KXH46919.1 - 8.5e-36 123.5 0.0 1.3e-35 122.8 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 KXH46919.1 - 8.7e-32 110.3 0.0 1.3e-31 109.7 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 KXH46919.1 - 2.1e-07 30.7 0.0 4.1e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KXH46919.1 - 6e-06 26.5 0.0 3.5e-05 24.1 0.0 2.3 2 1 0 2 2 2 1 Phosphopantetheine attachment site KR PF08659.10 KXH46919.1 - 0.17 11.8 0.0 1.8 8.5 0.0 2.6 2 1 0 2 2 2 0 KR domain Cu-oxidase_2 PF07731.14 KXH46920.1 - 6.2e-46 155.5 9.6 3.3e-43 146.7 1.3 3.8 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 KXH46920.1 - 9e-40 135.4 2.1 9e-40 135.4 2.1 3.9 5 0 0 5 5 5 2 Multicopper oxidase Cu-oxidase PF00394.22 KXH46920.1 - 1.3e-33 116.4 2.7 5.2e-33 114.4 0.4 2.7 3 0 0 3 3 3 1 Multicopper oxidase MIOX PF05153.15 KXH46921.1 - 5.2e-122 406.2 0.2 7.3e-122 405.7 0.2 1.2 1 0 0 1 1 1 1 Myo-inositol oxygenase HD PF01966.22 KXH46921.1 - 0.0035 17.5 0.0 0.61 10.3 0.0 2.5 2 0 0 2 2 2 2 HD domain Peptidase_A6 PF01829.16 KXH46921.1 - 0.081 12.2 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 Peptidase A6 family Fungal_trans_2 PF11951.8 KXH46922.1 - 7.6e-07 28.3 0.1 1.4e-06 27.4 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH46922.1 - 3.4e-05 23.9 7.6 6.3e-05 23.0 7.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.24 KXH46923.1 - 1.4e-86 291.2 18.3 1.7e-86 290.9 18.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH46923.1 - 2.1e-16 59.8 20.6 5e-14 52.0 18.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KXH46923.1 - 2.7e-05 23.2 4.8 2.7e-05 23.2 4.8 2.3 2 0 0 2 2 2 1 MFS_1 like family MFS_2 PF13347.6 KXH46923.1 - 0.0012 17.5 2.5 0.0012 17.5 2.5 2.3 2 1 1 3 3 3 1 MFS/sugar transport protein Tetraspanin PF00335.20 KXH46923.1 - 0.013 15.2 0.6 0.013 15.2 0.6 2.0 2 0 0 2 2 2 0 Tetraspanin family Claudin_3 PF06653.11 KXH46923.1 - 0.1 12.5 8.2 0.2 11.6 0.9 2.6 2 0 0 2 2 2 0 Tight junction protein, Claudin-like DUF3226 PF11536.8 KXH46923.1 - 0.13 11.9 0.0 9.1 5.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3226) DUF4131 PF13567.6 KXH46923.1 - 0.31 10.7 12.3 1.3 8.7 0.1 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) MFS_1 PF07690.16 KXH46924.1 - 7.5e-28 97.5 24.3 7.5e-28 97.5 24.3 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily SpoVAB PF13782.6 KXH46924.1 - 0.04 14.2 0.4 0.04 14.2 0.4 2.6 2 0 0 2 2 2 0 Stage V sporulation protein AB Fungal_trans PF04082.18 KXH46925.1 - 3e-27 95.3 0.0 5.2e-27 94.5 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH46925.1 - 5.5e-08 32.8 9.7 9.6e-08 32.0 9.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldo_ket_red PF00248.21 KXH46926.1 - 1.2e-51 175.7 0.0 1.1e-50 172.5 0.0 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family ComX PF05952.12 KXH46926.1 - 0.072 13.0 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 Bacillus competence pheromone ComX NAD_binding_4 PF07993.12 KXH46927.1 - 5.8e-41 140.4 0.0 1e-40 139.6 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 KXH46927.1 - 5.1e-37 127.5 0.0 8.2e-37 126.8 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 KXH46927.1 - 1.2e-11 44.6 0.0 2.9e-11 43.3 0.0 1.7 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family AAA_33 PF13671.6 KXH46927.1 - 1.9e-11 44.3 0.0 4.3e-11 43.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain PP-binding PF00550.25 KXH46927.1 - 1.9e-09 37.7 0.8 6.4e-09 36.0 0.3 2.3 2 0 0 2 2 1 1 Phosphopantetheine attachment site SKI PF01202.22 KXH46927.1 - 1.4e-08 35.0 0.0 2.8e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Shikimate kinase APS_kinase PF01583.20 KXH46927.1 - 1.7e-06 28.1 0.0 3.1e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_18 PF13238.6 KXH46927.1 - 2.5e-06 28.1 0.0 7e-06 26.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 KXH46927.1 - 5.1e-05 23.7 0.0 0.00013 22.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 KXH46927.1 - 6.3e-05 22.8 0.3 0.00016 21.4 0.0 1.9 2 0 0 2 2 2 1 Cytidylate kinase AAA_16 PF13191.6 KXH46927.1 - 0.00079 19.9 0.1 0.0032 17.9 0.0 2.1 2 0 0 2 2 1 1 AAA ATPase domain AAA_25 PF13481.6 KXH46927.1 - 0.0019 17.8 0.5 0.0089 15.6 0.2 2.2 1 1 1 2 2 2 1 AAA domain AAA PF00004.29 KXH46927.1 - 0.002 18.5 0.1 0.0062 17.0 0.1 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) KR PF08659.10 KXH46927.1 - 0.0022 17.9 0.2 0.034 14.1 0.1 2.4 2 0 0 2 2 2 1 KR domain Zeta_toxin PF06414.12 KXH46927.1 - 0.003 16.9 0.0 0.0069 15.7 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin Semialdhyde_dh PF01118.24 KXH46927.1 - 0.0053 17.2 0.0 0.013 15.9 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain B12-binding PF02310.19 KXH46927.1 - 0.012 15.7 0.1 1.7 8.7 0.0 2.9 2 0 0 2 2 2 0 B12 binding domain ABC_tran PF00005.27 KXH46927.1 - 0.022 15.2 0.0 0.052 14.1 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_PrkA PF08298.11 KXH46927.1 - 0.03 13.2 0.0 0.063 12.2 0.0 1.4 1 0 0 1 1 1 0 PrkA AAA domain IstB_IS21 PF01695.17 KXH46927.1 - 0.043 13.6 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein Polysacc_synt_2 PF02719.15 KXH46927.1 - 0.044 12.9 0.0 0.073 12.2 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NACHT PF05729.12 KXH46927.1 - 0.049 13.5 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 NACHT domain dNK PF01712.19 KXH46927.1 - 0.065 13.1 0.1 1.8 8.4 0.0 2.4 2 0 0 2 2 2 0 Deoxynucleoside kinase Cytidylate_kin2 PF13189.6 KXH46927.1 - 0.072 13.2 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 Cytidylate kinase-like family 3Beta_HSD PF01073.19 KXH46927.1 - 0.081 11.9 0.0 0.29 10.1 0.0 1.8 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family AAA_29 PF13555.6 KXH46927.1 - 0.089 12.5 0.0 0.24 11.1 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain NB-ARC PF00931.22 KXH46927.1 - 0.092 11.9 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_22 PF13401.6 KXH46927.1 - 0.12 12.7 0.0 0.37 11.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain CobU PF02283.16 KXH46927.1 - 0.18 11.4 0.3 2.9 7.5 0.0 2.4 2 0 0 2 2 2 0 Cobinamide kinase / cobinamide phosphate guanyltransferase T2SSE PF00437.20 KXH46927.1 - 0.19 10.8 1.4 0.39 9.7 0.1 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein Lactamase_B PF00753.27 KXH46928.1 - 5.1e-09 36.4 0.5 8.8e-09 35.6 0.5 1.4 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KXH46928.1 - 0.011 15.3 0.1 0.033 13.7 0.3 1.8 1 1 1 2 2 2 0 Beta-lactamase superfamily domain Varsurf_PPLC PF03490.13 KXH46929.1 - 0.017 15.0 0.3 0.062 13.3 0.0 2.0 2 0 0 2 2 2 0 Variant-surface-glycoprotein phospholipase C DUF5122 PF17164.4 KXH46930.1 - 0.22 11.9 0.4 0.46 10.8 0.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5122) beta-propeller Macro PF01661.21 KXH46931.1 - 8.9e-27 93.5 0.0 1.5e-26 92.7 0.0 1.4 1 0 0 1 1 1 1 Macro domain Egh16-like PF11327.8 KXH46932.1 - 6.2e-52 176.7 9.7 8.3e-52 176.3 9.7 1.2 1 0 0 1 1 1 1 Egh16-like virulence factor Amino_oxidase PF01593.24 KXH46933.1 - 7.3e-40 137.6 0.3 9.3e-39 134.0 0.3 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KXH46933.1 - 1e-05 25.6 0.0 2.7e-05 24.3 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain YdjM PF04307.14 KXH46933.1 - 0.028 13.7 0.0 0.055 12.8 0.0 1.4 1 0 0 1 1 1 0 LexA-binding, inner membrane-associated putative hydrolase Pkinase PF00069.25 KXH46934.1 - 2.7e-17 63.0 0.0 5.4e-17 62.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXH46934.1 - 6.1e-09 35.5 0.0 8.7e-08 31.8 0.0 2.2 2 1 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 KXH46934.1 - 0.14 11.1 0.0 0.28 10.1 0.0 1.4 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase PF00069.25 KXH46935.1 - 7e-17 61.7 0.0 1.3e-16 60.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain R2K_2 PF18299.1 KXH46936.1 - 0.089 12.6 0.0 0.096 12.5 0.0 1.2 1 0 0 1 1 1 0 ATP-grasp domain, R2K clade family 2 GPR15L PF15854.5 KXH46938.1 - 0.031 14.5 0.2 0.068 13.4 0.2 1.5 1 0 0 1 1 1 0 G-protein coupled receptor ligand 15 RPS31 PF17067.5 KXH46938.1 - 0.14 12.4 0.1 0.24 11.6 0.1 1.4 1 0 0 1 1 1 0 Ribosomal protein S31e DUF3328 PF11807.8 KXH46940.1 - 1.9e-10 40.9 10.5 2.6e-09 37.2 4.2 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF3328) DUF3328 PF11807.8 KXH46941.1 - 6.6e-29 101.3 5.0 1.7e-28 99.9 5.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) Fip1 PF05182.13 KXH46942.1 - 9.1e-21 73.1 1.3 2e-20 72.0 1.3 1.5 1 0 0 1 1 1 1 Fip1 motif Nucleoporin_FG PF13634.6 KXH46943.1 - 4.8e-17 62.6 102.6 4.5e-08 33.8 35.2 3.6 2 1 2 4 4 4 3 Nucleoporin FG repeat region DUF1640 PF07798.11 KXH46943.1 - 0.0083 16.2 0.2 0.044 13.8 0.0 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF1640) Prominin PF05478.11 KXH46943.1 - 0.026 12.5 1.6 0.044 11.8 0.4 1.7 2 0 0 2 2 2 0 Prominin SAM_Exu PF18609.1 KXH46943.1 - 0.051 13.7 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 Exuperantia SAM-like domain TFIIA PF03153.13 KXH46943.1 - 0.059 13.4 10.8 0.089 12.8 10.8 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Tup_N PF08581.10 KXH46943.1 - 0.067 13.5 3.2 0.12 12.7 0.0 2.5 3 0 0 3 3 3 0 Tup N-terminal DUF812 PF05667.11 KXH46943.1 - 0.078 11.8 0.3 1.4 7.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF812) Orthopox_C10L PF07020.11 KXH46943.1 - 3.3 8.5 39.3 7.7 7.3 5.4 4.6 1 1 2 3 3 3 0 Orthopoxvirus C10L protein RNA_pol_3_Rpc31 PF11705.8 KXH46944.1 - 3.6e-62 210.6 4.8 4.3e-62 210.3 4.8 1.0 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 Fungal_trans PF04082.18 KXH46962.1 - 3.2e-19 69.0 0.0 5e-19 68.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH46962.1 - 0.00014 21.9 8.1 0.00022 21.3 8.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Lar_restr_allev PF14354.6 KXH46962.1 - 0.56 10.6 3.4 1.1 9.6 3.4 1.5 1 0 0 1 1 1 0 Restriction alleviation protein Lar Aa_trans PF01490.18 KXH46963.1 - 5e-73 246.2 35.3 5.8e-73 245.9 35.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein MWFE PF15879.5 KXH46963.1 - 0.25 11.5 0.5 14 5.9 0.2 3.1 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase MWFE subunit Asp PF00026.23 KXH46964.1 - 8.1e-67 225.9 5.1 1.1e-66 225.5 5.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KXH46964.1 - 6.6e-10 39.5 5.4 5e-08 33.4 2.5 2.9 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KXH46964.1 - 0.004 17.8 0.0 0.13 12.9 0.0 3.1 2 1 0 2 2 2 1 Aspartyl protease TAXi_C PF14541.6 KXH46964.1 - 0.094 12.5 0.0 0.23 11.2 0.0 1.8 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal PPTA PF01239.22 KXH46966.1 - 1.5e-06 27.7 11.5 0.0037 16.9 0.3 3.8 3 0 0 3 3 3 2 Protein prenyltransferase alpha subunit repeat CHD5 PF04420.14 KXH46967.1 - 3.3e-60 202.5 2.9 4.3e-60 202.2 2.9 1.1 1 0 0 1 1 1 1 CHD5-like protein Peptidase_S49_N PF08496.10 KXH46967.1 - 0.15 12.2 1.1 0.2 11.7 0.3 1.6 2 0 0 2 2 2 0 Peptidase family S49 N-terminal DUF747 PF05346.11 KXH46967.1 - 0.18 11.3 0.0 0.21 11.0 0.0 1.2 1 1 0 1 1 1 0 Eukaryotic membrane protein family V_ATPase_I PF01496.19 KXH46968.1 - 0 1045.6 0.0 0 1045.4 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family CheZ PF04344.13 KXH46968.1 - 0.024 14.6 2.3 0.6 10.0 0.1 2.3 2 0 0 2 2 2 0 Chemotaxis phosphatase, CheZ SesA PF17107.5 KXH46968.1 - 0.093 12.9 1.5 0.99 9.6 0.1 2.7 3 0 0 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases DUF1515 PF07439.11 KXH46968.1 - 0.16 12.0 0.6 0.71 9.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) Snapin_Pallidin PF14712.6 KXH46968.1 - 1.1 9.8 4.2 27 5.3 0.8 2.7 2 1 0 2 2 2 0 Snapin/Pallidin DUF3552 PF12072.8 KXH46968.1 - 1.1 8.6 4.3 9.4 5.6 0.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) CPSF73-100_C PF11718.8 KXH46969.1 - 1e-83 280.2 0.0 1.5e-83 279.6 0.0 1.2 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 KXH46969.1 - 1.1e-29 102.9 0.0 3e-29 101.5 0.0 1.7 2 0 0 2 2 2 1 Beta-Casp domain Lactamase_B PF00753.27 KXH46969.1 - 1.2e-18 67.8 0.5 2.5e-18 66.8 0.5 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 KXH46969.1 - 9.2e-18 64.4 0.0 1.6e-17 63.6 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain RMMBL PF07521.12 KXH46969.1 - 5.2e-12 45.5 0.0 1.2e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 KXH46969.1 - 1.5e-05 24.6 0.5 3.7e-05 23.4 0.5 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KXH46969.1 - 1.6e-05 24.9 0.0 1.6e-05 24.9 0.0 1.9 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Beta_lactamase3 PF17030.5 KXH46969.1 - 0.12 11.6 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 Putative beta-lactamase-like family DUF4106 PF13388.6 KXH46969.1 - 0.12 11.6 1.0 0.2 10.9 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) TAF4 PF05236.14 KXH46970.1 - 8.4e-25 88.1 8.9 3.6e-21 76.1 7.2 2.2 2 0 0 2 2 2 2 Transcription initiation factor TFIID component TAF4 family Abhydrolase_6 PF12697.7 KXH46971.1 - 6.3e-06 26.9 3.0 1.1e-05 26.2 3.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXH46971.1 - 9e-05 21.8 0.1 0.00024 20.5 0.1 1.6 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KXH46971.1 - 0.0013 18.4 0.5 0.0041 16.8 0.5 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Aldose_epim PF01263.20 KXH46973.1 - 6.1e-48 163.7 0.5 8.3e-48 163.2 0.5 1.2 1 0 0 1 1 1 1 Aldose 1-epimerase Methyltransf_23 PF13489.6 KXH46976.1 - 7.6e-12 45.4 0.0 9.9e-12 45.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KXH46976.1 - 0.0011 18.7 0.0 0.003 17.3 0.0 1.7 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 KXH46976.1 - 0.012 16.3 0.0 0.068 13.9 0.0 2.3 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.6 KXH46976.1 - 0.038 13.8 0.3 3.6 7.4 0.0 2.3 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.12 KXH46976.1 - 0.1 13.3 0.0 3.3 8.5 0.0 2.8 2 1 0 2 2 2 0 Methyltransferase domain Arg_repressor PF01316.21 KXH46976.1 - 0.12 12.2 0.1 0.23 11.2 0.1 1.4 1 0 0 1 1 1 0 Arginine repressor, DNA binding domain Synaptobrevin PF00957.21 KXH47041.1 - 2.9e-32 110.3 0.5 3.8e-32 109.9 0.5 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 KXH47041.1 - 8.9e-30 102.6 0.0 1.5e-29 101.9 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain SUV3_C PF12513.8 KXH47042.1 - 3.2e-17 62.2 0.3 8.8e-17 60.8 0.3 1.8 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.31 KXH47042.1 - 1.5e-10 41.4 0.0 5.5e-10 39.6 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Suv3_C_1 PF18147.1 KXH47042.1 - 4.8e-09 35.9 0.9 7.6e-09 35.3 0.0 1.9 2 0 0 2 2 2 1 Suv3 C-terminal domain 1 DUF4771 PF15995.5 KXH47042.1 - 0.089 13.1 0.2 0.23 11.7 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4771) Paf1 PF03985.13 KXH47042.1 - 0.21 10.6 6.3 0.29 10.1 4.8 1.8 2 0 0 2 2 2 0 Paf1 Peptidase_C12 PF01088.21 KXH47043.1 - 5e-56 189.8 0.0 6e-56 189.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Fungal_trans PF04082.18 KXH47046.1 - 3.9e-24 85.1 1.0 6e-24 84.5 0.1 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH47046.1 - 2.5e-07 30.7 12.6 5.6e-07 29.6 12.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_23 PF13489.6 KXH47048.1 - 1.2e-20 74.0 0.0 1.8e-20 73.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH47048.1 - 1.1e-12 48.4 0.0 6e-12 46.1 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH47048.1 - 1.9e-11 44.0 0.0 0.00011 22.0 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 KXH47048.1 - 4.5e-09 36.8 0.0 1.2e-08 35.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH47048.1 - 3.5e-08 34.1 0.0 6e-07 30.1 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXH47048.1 - 0.00043 19.7 0.0 0.52 9.6 0.0 2.1 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family MTS PF05175.14 KXH47048.1 - 0.00098 18.7 0.0 0.0022 17.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 KXH47048.1 - 0.012 15.0 0.0 0.03 13.7 0.0 1.5 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.17 KXH47048.1 - 0.021 14.3 0.0 0.17 11.4 0.0 2.0 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_16 PF10294.9 KXH47048.1 - 0.14 11.9 0.0 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase FtsJ PF01728.19 KXH47048.1 - 0.19 11.8 0.0 0.46 10.6 0.0 1.6 1 1 1 2 2 2 0 FtsJ-like methyltransferase FMN_dh PF01070.18 KXH47049.1 - 1.3e-98 330.2 1.2 4.8e-98 328.4 1.2 1.7 1 1 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 KXH47049.1 - 4.1e-20 71.7 0.0 8.7e-20 70.7 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 KXH47049.1 - 9.3e-07 28.3 0.2 1.4e-06 27.7 0.2 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 KXH47049.1 - 5.1e-05 22.4 0.9 0.00029 20.0 0.2 2.0 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 KXH47049.1 - 0.004 16.6 0.5 0.0071 15.8 0.5 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase ThiG PF05690.14 KXH47049.1 - 0.019 14.3 0.1 2.4 7.4 0.2 2.4 1 1 0 2 2 2 0 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 KXH47049.1 - 0.036 13.5 0.1 0.088 12.3 0.1 1.6 2 0 0 2 2 2 0 Histidine biosynthesis protein PIEZO PF15917.5 KXH47050.1 - 0.75 9.2 18.1 1.5 8.3 9.6 2.1 2 0 0 2 2 2 0 Piezo FliD_N PF02465.18 KXH47050.1 - 3.5 8.4 5.4 40 5.0 0.1 2.3 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus 3Beta_HSD PF01073.19 KXH47052.1 - 1e-08 34.5 0.0 1.7e-08 33.8 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KXH47052.1 - 1.3e-08 34.3 0.0 2.3e-07 30.2 0.0 2.0 2 0 0 2 2 2 1 Male sterility protein Epimerase PF01370.21 KXH47052.1 - 1.2e-07 31.5 0.0 3.2e-07 30.1 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KXH47052.1 - 1.7e-05 24.5 0.1 2.6e-05 23.9 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family GDP_Man_Dehyd PF16363.5 KXH47052.1 - 0.03 13.7 0.0 0.041 13.3 0.0 1.1 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Sugar_tr PF00083.24 KXH47053.1 - 1.3e-86 291.3 17.8 1.4e-86 291.1 17.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH47053.1 - 1.4e-30 106.5 13.6 1.4e-30 106.5 13.6 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Hanta_nucleocap PF00846.18 KXH47053.1 - 0.22 9.9 0.0 0.35 9.3 0.0 1.2 1 0 0 1 1 1 0 Hantavirus nucleocapsid protein HET PF06985.11 KXH47054.1 - 2.4e-23 83.1 0.0 8.8e-23 81.3 0.0 1.9 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DEAD PF00270.29 KXH47055.1 - 3.6e-41 140.8 0.1 5.8e-41 140.2 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXH47055.1 - 2.2e-30 105.2 0.2 5e-29 100.9 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXH47055.1 - 4.5e-08 33.3 0.0 1.1e-07 32.1 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KXH47055.1 - 0.056 13.8 0.0 0.09 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain Methyltransf_23 PF13489.6 KXH47056.1 - 7.2e-13 48.7 0.0 1.3e-12 47.9 0.0 1.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH47056.1 - 1.7e-10 41.6 0.0 2.4e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH47056.1 - 6.8e-10 39.5 0.0 1.1e-09 38.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH47056.1 - 1.2e-08 35.5 0.0 2.2e-08 34.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH47056.1 - 8.3e-07 28.9 0.0 1.2e-06 28.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXH47056.1 - 0.15 11.6 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Sugar_tr PF00083.24 KXH47057.1 - 2e-80 270.8 19.3 2.3e-80 270.7 19.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH47057.1 - 2.7e-29 102.2 38.3 2.4e-19 69.5 15.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KXH47057.1 - 1.3e-05 23.8 1.0 1.3e-05 23.8 1.0 1.9 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family Trp_oprn_chp PF09534.10 KXH47057.1 - 0.51 10.1 14.0 3.7 7.3 9.2 3.2 2 1 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Phage_holin_3_2 PF04550.12 KXH47057.1 - 7.5 7.2 8.5 0.48 11.0 1.4 2.7 2 1 1 3 3 3 0 Phage holin family 2 AflR PF08493.10 KXH47058.1 - 1.8e-10 40.8 3.0 5e-10 39.3 3.0 1.8 1 1 0 1 1 1 1 Aflatoxin regulatory protein Zn_clus PF00172.18 KXH47058.1 - 8.6e-09 35.4 10.8 2e-08 34.2 10.8 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_2 PF00891.18 KXH47059.1 - 8.8e-20 70.9 0.0 3.4e-19 69.0 0.0 1.8 1 1 0 1 1 1 1 O-methyltransferase domain Methyltransf_25 PF13649.6 KXH47059.1 - 4.1e-05 24.2 0.0 0.00021 21.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 KXH47059.1 - 0.0052 16.4 0.0 0.012 15.2 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_31 PF13847.6 KXH47059.1 - 0.0055 16.5 0.0 0.014 15.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 KXH47060.1 - 1.9e-27 96.0 0.0 3e-27 95.3 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain FAD_binding_3 PF01494.19 KXH47060.1 - 1.6e-17 63.8 1.0 1.3e-05 24.6 0.0 3.2 2 1 0 3 3 3 3 FAD binding domain NAD_binding_8 PF13450.6 KXH47060.1 - 0.0004 20.6 0.0 0.0013 18.9 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DUF938 PF06080.12 KXH47060.1 - 0.051 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Pyr_redox PF00070.27 KXH47060.1 - 0.19 12.3 0.0 0.59 10.7 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ketoacyl-synt PF00109.26 KXH47061.1 - 1.9e-74 250.4 0.4 6.3e-74 248.7 0.1 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain SAT PF16073.5 KXH47061.1 - 1.4e-70 237.8 2.0 1.4e-70 237.8 2.0 2.2 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Acyl_transf_1 PF00698.21 KXH47061.1 - 2.3e-38 132.5 0.6 5e-38 131.4 0.6 1.5 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KXH47061.1 - 1.2e-33 115.7 4.4 9.5e-33 112.7 3.0 2.9 3 0 0 3 3 3 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.20 KXH47061.1 - 3.2e-25 89.6 0.1 1.5e-24 87.4 0.0 2.2 2 0 0 2 2 2 1 Thioesterase domain PS-DH PF14765.6 KXH47061.1 - 8e-15 54.8 0.0 2.4e-14 53.3 0.0 1.7 2 0 0 2 2 2 1 Polyketide synthase dehydratase PP-binding PF00550.25 KXH47061.1 - 5.6e-10 39.4 0.9 1.9e-09 37.8 0.9 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.23 KXH47061.1 - 1.1e-05 25.0 0.2 7.9e-05 22.1 0.0 2.3 2 0 0 2 2 2 1 Thiolase, N-terminal domain KAsynt_C_assoc PF16197.5 KXH47061.1 - 1.4e-05 25.6 0.0 3.5e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension ACP_syn_III PF08545.10 KXH47061.1 - 0.087 12.7 0.1 0.43 10.5 0.0 2.2 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Abhydrolase_1 PF00561.20 KXH47061.1 - 0.095 12.3 0.0 0.98 9.0 0.0 2.3 2 0 0 2 2 2 0 alpha/beta hydrolase fold Nuc_recep-AF1 PF11825.8 KXH47061.1 - 0.19 11.8 4.0 0.91 9.6 4.0 2.2 1 0 0 1 1 1 0 Nuclear/hormone receptor activator site AF-1 FAD_binding_4 PF01565.23 KXH47062.1 - 2.1e-22 79.4 0.2 3.8e-22 78.5 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_10 PF13460.6 KXH47063.1 - 2e-14 53.9 0.0 3.1e-14 53.3 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KXH47063.1 - 2.2e-14 53.6 0.1 3.2e-14 53.1 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family F420_oxidored PF03807.17 KXH47063.1 - 0.0027 18.2 0.0 0.0056 17.2 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_7 PF13241.6 KXH47063.1 - 0.0032 17.9 0.0 0.008 16.6 0.0 1.7 1 0 0 1 1 1 1 Putative NAD(P)-binding Epimerase PF01370.21 KXH47063.1 - 0.0035 16.9 0.0 0.0074 15.8 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DFP PF04127.15 KXH47063.1 - 0.0035 17.2 0.2 0.037 13.9 0.0 2.3 2 1 0 2 2 2 1 DNA / pantothenate metabolism flavoprotein Shikimate_DH PF01488.20 KXH47063.1 - 0.014 15.4 0.0 0.027 14.5 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_2 PF03446.15 KXH47063.1 - 0.034 14.3 0.1 0.14 12.3 0.0 1.9 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Cu-oxidase_3 PF07732.15 KXH47064.1 - 9.5e-38 128.9 1.5 3.4e-37 127.1 0.1 2.5 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KXH47064.1 - 2.8e-31 108.1 3.6 6.8e-24 84.2 0.1 3.7 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 KXH47064.1 - 1.6e-14 54.3 0.0 6.5e-12 45.8 0.0 2.4 2 0 0 2 2 2 2 Multicopper oxidase ThiS PF02597.20 KXH47064.1 - 0.099 13.3 0.0 0.6 10.8 0.0 2.1 2 0 0 2 2 2 0 ThiS family Fasciclin PF02469.22 KXH47065.1 - 6.2e-30 104.0 0.0 9.3e-17 61.5 0.0 2.2 2 0 0 2 2 2 2 Fasciclin domain MFS_1 PF07690.16 KXH47066.1 - 9.5e-40 136.6 28.4 9.5e-40 136.6 28.4 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH47066.1 - 5.5e-14 51.9 11.2 1.3e-13 50.7 11.2 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter DUF1129 PF06570.11 KXH47066.1 - 0.041 13.4 0.3 0.041 13.4 0.3 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1129) DUF3817 PF12823.7 KXH47066.1 - 2 9.3 7.5 0.8 10.6 0.2 3.6 3 2 1 4 4 4 0 Domain of unknown function (DUF3817) EthD PF07110.11 KXH47068.1 - 8.6e-06 26.8 0.3 1.2e-05 26.4 0.3 1.2 1 0 0 1 1 1 1 EthD domain adh_short PF00106.25 KXH47069.1 - 2e-30 105.7 0.0 1.3e-22 80.2 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXH47069.1 - 8.9e-20 71.2 0.1 2.3e-15 56.8 0.1 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH47069.1 - 3.6e-10 40.0 0.0 5e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KXH47069.1 - 0.017 15.0 0.2 0.047 13.6 0.3 1.7 2 0 0 2 2 2 0 NAD(P)H-binding adh_short PF00106.25 KXH47071.1 - 1.7e-28 99.4 0.1 1.2e-25 90.1 0.1 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXH47071.1 - 4e-16 59.3 0.0 5.1e-15 55.7 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH47071.1 - 1.7e-07 31.4 0.4 3.2e-07 30.4 0.4 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KXH47071.1 - 8.1e-07 28.7 0.1 1.2e-06 28.2 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXH47071.1 - 0.014 14.8 0.1 0.024 14.1 0.1 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase NmrA PF05368.13 KXH47071.1 - 0.052 13.1 0.1 0.082 12.4 0.1 1.3 1 0 0 1 1 1 0 NmrA-like family NAD_binding_10 PF13460.6 KXH47071.1 - 0.075 12.9 0.2 0.12 12.2 0.1 1.4 1 1 0 1 1 1 0 NAD(P)H-binding Shikimate_DH PF01488.20 KXH47071.1 - 0.088 12.9 0.1 0.16 12.1 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase MFS_1 PF07690.16 KXH47072.1 - 8.1e-37 127.0 45.2 3.1e-35 121.8 46.4 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KXH47072.1 - 6.9e-12 44.6 25.6 9.6e-12 44.1 25.6 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KXH47072.1 - 5.7e-09 35.3 32.4 1.5e-06 27.4 16.7 3.2 3 1 0 3 3 3 2 Sugar (and other) transporter DUF5305 PF17231.2 KXH47072.1 - 0.2 11.1 0.1 8.2 5.8 0.0 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5305) Ferric_reduct PF01794.19 KXH47073.1 - 3.1e-21 75.8 11.1 8.9e-21 74.3 11.1 1.8 1 0 0 1 1 1 1 Ferric reductase like transmembrane component B_lectin PF01453.24 KXH47074.1 - 0.064 13.8 0.0 1.1 9.8 0.0 2.3 1 1 1 2 2 2 0 D-mannose binding lectin XPG_I_2 PF12813.7 KXH47075.1 - 8.1e-41 140.1 0.0 1.2e-40 139.5 0.0 1.2 1 0 0 1 1 1 1 XPG domain containing Pribosyltran_N PF13793.6 KXH47076.1 - 5.1e-43 145.7 0.2 4.5e-41 139.4 0.0 2.3 2 0 0 2 2 2 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 KXH47076.1 - 3.1e-35 121.9 0.0 1.5e-29 103.3 0.0 2.3 2 0 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 KXH47076.1 - 6.5e-09 35.5 0.0 8.9e-05 22.1 0.0 2.4 2 0 0 2 2 2 2 Phosphoribosyl transferase domain PAP_assoc PF03828.19 KXH47077.1 - 7.5e-17 61.3 0.0 5.8e-11 42.4 0.0 2.7 2 0 0 2 2 2 2 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 KXH47077.1 - 0.00043 20.5 0.0 0.00099 19.4 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain DUF1658 PF07871.11 KXH47077.1 - 0.22 11.5 4.7 0.069 13.1 0.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1658) TFIIF_alpha PF05793.12 KXH47078.1 - 2e-07 30.0 59.7 2e-07 30.0 59.7 1.8 2 1 0 2 2 2 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Bud13 PF09736.9 KXH47079.1 - 5.4e-50 169.6 5.8 5.4e-50 169.6 5.8 2.3 2 1 0 2 2 2 1 Pre-mRNA-splicing factor of RES complex TRAPPC-Trs85 PF12739.7 KXH47080.1 - 8.5e-116 387.3 0.0 3.7e-115 385.1 0.0 1.8 2 0 0 2 2 2 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit Snf7 PF03357.21 KXH47081.1 - 3.7e-18 65.7 12.5 6.4e-18 65.0 12.5 1.4 1 1 0 1 1 1 1 Snf7 HAUS-augmin3 PF14932.6 KXH47081.1 - 0.0018 17.9 4.5 0.0018 17.9 4.5 2.3 2 0 0 2 2 2 1 HAUS augmin-like complex subunit 3 AAA_23 PF13476.6 KXH47081.1 - 0.62 10.5 10.4 0.35 11.3 2.9 2.2 2 0 0 2 2 2 0 AAA domain Atg14 PF10186.9 KXH47081.1 - 2.1 7.4 6.6 0.18 10.8 0.7 1.9 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 UPF0242 PF06785.11 KXH47081.1 - 2.9 7.9 13.7 0.088 12.9 1.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus H-kinase_dim PF02895.14 KXH47081.1 - 3.7 8.0 12.2 1.5 9.3 0.9 3.9 4 1 0 4 4 4 0 Signal transducing histidine kinase, homodimeric domain AAA_13 PF13166.6 KXH47081.1 - 3.8 6.0 13.3 5.6 5.5 13.3 1.2 1 0 0 1 1 1 0 AAA domain YebO PF13974.6 KXH47081.1 - 9.2 6.4 8.1 0.35 11.0 1.5 2.0 2 0 0 2 2 2 0 YebO-like protein zf-C3HC4_2 PF13923.6 KXH47082.1 - 2.9e-11 43.0 13.2 2.9e-11 43.0 13.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXH47082.1 - 1.8e-07 30.9 19.9 4e-07 29.8 13.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KXH47082.1 - 7.4e-07 28.9 9.9 7.4e-07 28.9 9.9 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXH47082.1 - 1.7e-06 28.0 10.8 1.7e-06 28.0 10.8 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 KXH47082.1 - 1.2e-05 25.5 18.8 1.2e-05 25.5 12.7 2.3 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 KXH47082.1 - 1.5e-05 24.9 12.7 1.5e-05 24.9 12.7 2.2 2 0 0 2 2 2 1 zinc-RING finger domain SAP PF02037.27 KXH47082.1 - 2.9e-05 23.7 0.5 6.2e-05 22.7 0.1 1.8 2 0 0 2 2 2 1 SAP domain Prok-RING_4 PF14447.6 KXH47082.1 - 7.2e-05 22.6 14.5 0.0025 17.6 10.8 2.3 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KXH47082.1 - 7.4e-05 22.8 12.4 7.4e-05 22.8 12.4 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 KXH47082.1 - 0.00024 20.9 4.6 0.00024 20.9 4.6 1.9 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 KXH47082.1 - 0.00054 20.2 6.4 0.00054 20.2 6.4 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger domain Ribosomal_L4 PF00573.22 KXH47082.1 - 0.0012 18.6 4.3 0.21 11.3 0.2 2.2 2 0 0 2 2 2 2 Ribosomal protein L4/L1 family U-box PF04564.15 KXH47082.1 - 0.0018 18.4 0.0 0.005 17.0 0.0 1.7 1 0 0 1 1 1 1 U-box domain zf-RING_10 PF16685.5 KXH47082.1 - 0.017 15.2 7.2 0.034 14.3 7.2 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 Mob_synth_C PF06463.13 KXH47082.1 - 0.065 13.2 4.8 0.16 11.9 4.8 1.6 1 0 0 1 1 1 0 Molybdenum Cofactor Synthesis C zf-Di19 PF05605.12 KXH47082.1 - 3.9 7.8 8.6 0.84 10.0 0.1 2.8 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-RING_4 PF14570.6 KXH47082.1 - 7.4 6.5 15.3 0.13 12.1 6.1 2.5 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain CDC27 PF09507.10 KXH47083.1 - 2.2e-83 281.1 28.7 6.9e-83 279.4 28.7 1.7 1 1 0 1 1 1 1 DNA polymerase subunit Cdc27 Glyco_hydro_125 PF06824.11 KXH47084.1 - 4.7e-178 592.3 0.0 5.4e-178 592.1 0.0 1.0 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) MCM PF00493.23 KXH47085.1 - 8.6e-103 342.2 0.5 1.3e-102 341.7 0.5 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KXH47085.1 - 5.5e-39 132.9 0.7 9.6e-39 132.1 0.7 1.4 1 0 0 1 1 1 1 MCM OB domain MCM6_C PF18263.1 KXH47085.1 - 4.5e-31 107.3 0.1 9.3e-31 106.3 0.1 1.6 1 0 0 1 1 1 1 MCM6 C-terminal winged-helix domain MCM_N PF14551.6 KXH47085.1 - 1.8e-23 83.1 0.1 6.3e-23 81.3 0.1 2.0 1 0 0 1 1 1 1 MCM N-terminal domain MCM_lid PF17855.1 KXH47085.1 - 5.4e-23 81.2 0.3 2.7e-22 79.0 0.0 2.3 3 0 0 3 3 3 1 MCM AAA-lid domain Mg_chelatase PF01078.21 KXH47085.1 - 2.7e-07 30.2 0.0 7.6e-07 28.7 0.0 1.8 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KXH47085.1 - 0.0017 18.2 0.0 0.0055 16.6 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KXH47085.1 - 0.0019 17.9 0.0 0.0035 17.1 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain RNase_H2_suC PF08615.11 KXH47086.1 - 1.7e-28 99.6 0.0 2.2e-28 99.2 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) CMAS PF02353.20 KXH47087.1 - 3.7e-74 249.4 0.0 9.8e-74 248.1 0.0 1.6 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 KXH47087.1 - 1.7e-12 47.8 0.0 3.5e-12 46.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH47087.1 - 1.2e-11 45.1 0.0 2.3e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXH47087.1 - 2.4e-09 37.2 0.0 4.2e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH47087.1 - 3.6e-09 36.6 0.0 7e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH47087.1 - 9e-07 29.6 0.0 1.8e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KXH47087.1 - 0.0015 18.4 0.0 0.0028 17.4 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.7 KXH47087.1 - 0.015 15.2 0.0 0.026 14.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_3 PF01596.17 KXH47087.1 - 0.083 12.1 0.0 0.16 11.1 0.0 1.5 1 0 0 1 1 1 0 O-methyltransferase ADH_zinc_N PF00107.26 KXH47087.1 - 0.15 12.0 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase RrnaAD PF00398.20 KXH47087.1 - 0.21 10.7 0.0 0.36 9.8 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase RNase_T PF00929.24 KXH47088.1 - 3.8e-15 56.8 0.0 2.1e-14 54.4 0.0 2.0 1 1 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 KXH47088.1 - 0.0046 16.7 0.0 0.011 15.5 0.0 1.6 1 1 0 1 1 1 1 3'-5' exonuclease SOG2 PF10428.9 KXH47088.1 - 0.095 11.9 5.7 0.13 11.5 5.7 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein MOZ_SAS PF01853.18 KXH47089.1 - 3.7e-80 267.8 0.1 7.1e-80 266.9 0.1 1.5 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 KXH47089.1 - 9e-22 76.4 1.0 1.8e-21 75.5 1.0 1.6 1 0 0 1 1 1 1 MYST family zinc finger domain Tudor-knot PF11717.8 KXH47089.1 - 9.6e-16 57.4 0.0 2.6e-15 56.0 0.0 1.8 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Aminotran_1_2 PF00155.21 KXH47089.1 - 1.7e-12 47.2 0.0 2.7e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 KXH47089.1 - 0.00032 19.6 0.0 0.0012 17.8 0.0 1.7 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase Acetyltransf_7 PF13508.7 KXH47089.1 - 0.00052 20.4 0.0 0.0011 19.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXH47089.1 - 0.018 15.2 0.0 0.049 13.9 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Mito_carr PF00153.27 KXH47118.1 - 3.1e-51 171.3 6.1 6.5e-17 61.2 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein UcrQ PF02939.16 KXH47118.1 - 0.075 13.0 0.1 0.24 11.3 0.1 2.0 1 0 0 1 1 1 0 UcrQ family Mak10 PF04112.13 KXH47119.1 - 1.8e-64 216.3 0.0 6.6e-64 214.5 0.0 2.0 2 0 0 2 2 2 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase Alpha-E PF04168.12 KXH47119.1 - 0.019 14.8 0.2 0.07 12.9 0.0 1.8 2 0 0 2 2 2 0 A predicted alpha-helical domain with a conserved ER motif. ATP-synt_Eps PF04627.13 KXH47120.1 - 1e-23 83.1 0.9 1.3e-23 82.7 0.9 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain PMBR PF09373.10 KXH47120.1 - 0.094 12.9 0.1 0.15 12.3 0.1 1.3 1 0 0 1 1 1 0 Pseudomurein-binding repeat FAD_binding_3 PF01494.19 KXH47121.1 - 5.5e-21 75.2 0.0 1.3e-09 37.8 0.0 2.9 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.24 KXH47121.1 - 7.3e-06 25.8 0.0 0.017 14.8 0.0 2.3 1 1 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KXH47121.1 - 9.1e-06 25.0 0.0 0.013 14.6 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein SE PF08491.10 KXH47121.1 - 4.3e-05 22.7 0.0 0.0011 18.1 0.0 2.1 2 0 0 2 2 2 1 Squalene epoxidase NAD_binding_8 PF13450.6 KXH47121.1 - 0.00019 21.6 0.1 0.00055 20.1 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXH47121.1 - 0.009 15.3 0.0 0.025 13.8 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 KXH47121.1 - 0.026 14.2 0.0 0.056 13.1 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.27 KXH47121.1 - 0.12 12.9 0.0 0.79 10.3 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXH47121.1 - 0.12 11.0 0.0 0.19 10.4 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein AIP3 PF03915.13 KXH47122.1 - 6.3e-158 526.1 8.4 1e-157 525.4 8.4 1.4 1 0 0 1 1 1 1 Actin interacting protein 3 Lectin_N PF03954.14 KXH47122.1 - 0.042 13.6 0.5 0.32 10.7 0.1 2.7 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain RasGAP_C PF03836.15 KXH47122.1 - 0.056 13.6 2.3 0.74 10.0 0.2 3.4 4 0 0 4 4 4 0 RasGAP C-terminus NPV_P10 PF05531.12 KXH47122.1 - 0.37 11.3 7.6 0.21 12.1 0.8 3.5 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein GIT1_C PF12205.8 KXH47122.1 - 0.71 10.0 2.7 1.8 8.7 0.3 2.7 2 1 0 3 3 3 0 G protein-coupled receptor kinase-interacting protein 1 C term Baculo_PEP_C PF04513.12 KXH47122.1 - 1.8 8.6 8.1 2 8.5 0.0 3.6 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus BNIP3 PF06553.12 KXH47122.1 - 5.4 6.6 9.4 0.17 11.5 2.1 2.2 2 0 0 2 2 2 0 BNIP3 Fib_alpha PF08702.10 KXH47122.1 - 5.9 7.1 8.1 34 4.6 0.1 4.1 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Pro_isomerase PF00160.21 KXH47123.1 - 1e-43 149.3 0.0 1.2e-43 149.2 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD MFS_1 PF07690.16 KXH47124.1 - 3.4e-29 101.9 28.6 3.4e-29 101.9 28.6 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily SNF2_N PF00176.23 KXH47125.1 - 9.1e-06 24.6 0.0 1.8e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 KXH47125.1 - 1.7e-05 24.9 0.0 4.6e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.9 KXH47125.1 - 0.0089 15.3 0.0 0.016 14.4 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Helicase_C PF00271.31 KXH47125.1 - 0.019 15.3 0.0 0.11 12.9 0.0 2.3 2 0 0 2 2 2 0 Helicase conserved C-terminal domain HSF_DNA-bind PF00447.17 KXH47126.1 - 1.7e-28 99.1 0.4 3.8e-28 97.9 0.4 1.6 1 0 0 1 1 1 1 HSF-type DNA-binding Ets PF00178.22 KXH47126.1 - 0.058 13.9 0.1 0.14 12.6 0.1 1.6 1 0 0 1 1 1 0 Ets-domain Pro_isomerase PF00160.21 KXH47127.1 - 7.2e-41 140.1 0.0 1.5e-40 139.0 0.0 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DS PF01916.17 KXH47129.1 - 5.7e-130 432.7 0.0 6.6e-130 432.5 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase Myb_DNA-binding PF00249.31 KXH47130.1 - 1.1e-07 31.9 0.0 0.0009 19.4 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain FA_desaturase PF00487.24 KXH47145.1 - 5.6e-25 88.6 21.4 1.1e-24 87.7 21.4 1.4 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 KXH47145.1 - 0.00017 21.8 0.0 0.00035 20.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) p450 PF00067.22 KXH47146.1 - 5.9e-51 173.7 0.0 6.9e-51 173.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_2 PF00891.18 KXH47147.1 - 5.6e-11 42.1 0.0 2.7e-10 39.9 0.0 1.9 1 1 0 1 1 1 1 O-methyltransferase domain MTS PF05175.14 KXH47147.1 - 0.00057 19.5 0.0 0.0013 18.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 KXH47147.1 - 0.00081 20.0 0.0 0.0018 18.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Dimerisation2 PF16864.5 KXH47147.1 - 0.00091 19.2 0.0 0.0016 18.4 0.0 1.4 1 0 0 1 1 1 1 Dimerisation domain Dimerisation PF08100.11 KXH47147.1 - 0.0019 18.2 0.1 0.0049 16.9 0.1 1.7 1 0 0 1 1 1 1 Dimerisation domain Methyltransf_23 PF13489.6 KXH47147.1 - 0.0028 17.5 0.0 0.005 16.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH47147.1 - 0.0048 16.7 0.0 0.009 15.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Rogdi_lz PF10259.9 KXH47147.1 - 0.11 12.0 0.6 0.76 9.2 0.1 2.2 2 0 0 2 2 2 0 Rogdi leucine zipper containing protein Methyltransf_12 PF08242.12 KXH47147.1 - 0.17 12.6 0.0 0.42 11.4 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain FAD_binding_3 PF01494.19 KXH47148.1 - 2.4e-07 30.3 0.0 4.1e-07 29.6 0.0 1.3 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KXH47148.1 - 0.061 12.6 0.0 0.099 11.9 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Fungal_trans PF04082.18 KXH47150.1 - 5.9e-07 28.8 0.1 8.6e-07 28.2 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain HMG_CoA_synt_C PF08540.10 KXH47151.1 - 1.2e-92 310.6 0.1 1.6e-92 310.1 0.1 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 KXH47151.1 - 3.7e-79 264.6 0.1 5.2e-79 264.1 0.1 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal 2OG-FeII_Oxy_2 PF13532.6 KXH47152.1 - 1.4e-13 51.5 0.0 1.7e-13 51.2 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 KXH47152.1 - 0.002 18.6 0.0 0.0032 17.9 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CLTH PF10607.9 KXH47157.1 - 1e-31 109.8 0.0 1.9e-31 109.0 0.0 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.28 KXH47157.1 - 1e-24 87.0 0.2 1.8e-24 86.2 0.2 1.4 1 0 0 1 1 1 1 SPRY domain LisH PF08513.11 KXH47157.1 - 5e-06 26.3 0.4 1.2e-05 25.1 0.1 1.9 2 0 0 2 2 2 1 LisH INO80_Ies4 PF08193.11 KXH47158.1 - 5.5e-81 272.1 15.1 7.1e-81 271.8 15.1 1.1 1 0 0 1 1 1 1 INO80 complex subunit Ies4 KCNQC3-Ank-G_bd PF11956.8 KXH47158.1 - 0.0079 16.5 0.5 0.0079 16.5 0.5 2.0 2 0 0 2 2 2 1 Ankyrin-G binding motif of KCNQ2-3 IDO PF01231.18 KXH47161.1 - 6.2e-36 124.1 0.0 8.3e-36 123.7 0.0 1.1 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase MFS_1 PF07690.16 KXH47162.1 - 4.9e-45 154.0 37.7 4.9e-45 154.0 37.7 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH47162.1 - 9e-07 28.1 14.5 9e-07 28.1 14.5 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter PTR2 PF00854.21 KXH47162.1 - 0.0017 17.3 5.7 0.037 12.9 1.7 2.5 1 1 1 3 3 3 2 POT family Aldedh PF00171.22 KXH47163.1 - 8.5e-14 50.9 11.7 2.8e-10 39.3 8.0 2.9 2 1 0 2 2 2 2 Aldehyde dehydrogenase family DUF5021 PF16424.5 KXH47163.1 - 0.13 12.1 0.7 0.3 10.9 0.4 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF5021) DUF4376 PF14301.6 KXH47163.1 - 1.2 9.6 3.8 0.64 10.4 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4376) AIM24 PF01987.17 KXH47164.1 - 7.4e-52 176.1 0.6 8.9e-52 175.8 0.6 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 Amidohydro_2 PF04909.14 KXH47165.1 - 4.1e-25 89.1 0.5 2.6e-24 86.5 0.5 1.9 1 1 0 1 1 1 1 Amidohydrolase Spt5-NGN PF03439.13 KXH47165.1 - 0.11 12.4 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 Early transcription elongation factor of RNA pol II, NGN section AMPK1_CBM PF16561.5 KXH47166.1 - 0.021 15.0 0.0 0.057 13.6 0.0 1.7 1 1 0 1 1 1 0 Glycogen recognition site of AMP-activated protein kinase Sec3_C PF09763.9 KXH47166.1 - 0.52 8.6 4.1 0.59 8.5 4.1 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec3 Presenilin PF01080.17 KXH47166.1 - 1.2 7.8 4.7 1.6 7.4 4.7 1.1 1 0 0 1 1 1 0 Presenilin NPR3 PF03666.13 KXH47166.1 - 2.3 6.9 8.4 3 6.5 8.4 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 MAP70 PF07058.11 KXH47166.1 - 7.5 5.2 7.0 10 4.7 7.0 1.1 1 0 0 1 1 1 0 Microtubule-associated protein 70 HD PF01966.22 KXH47167.1 - 4.6e-06 26.9 0.2 2.4e-05 24.6 0.1 2.0 2 0 0 2 2 2 1 HD domain Fasciclin PF02469.22 KXH47169.1 - 6.3e-26 91.1 0.2 3.7e-18 66.0 0.0 2.5 2 1 0 2 2 2 2 Fasciclin domain SOG2 PF10428.9 KXH47170.1 - 3.1 6.9 7.3 3.7 6.6 7.3 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein GFA PF04828.14 KXH47171.1 - 7.1e-25 87.2 0.0 1e-24 86.7 0.0 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme DZR PF12773.7 KXH47171.1 - 0.12 12.4 3.5 0.85 9.7 0.2 2.5 2 1 0 2 2 2 0 Double zinc ribbon DUF1365 PF07103.11 KXH47172.1 - 1.9e-61 207.8 0.0 2.9e-61 207.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1365) MBF1 PF08523.10 KXH47173.1 - 2.5e-17 63.1 1.9 2.7e-17 63.0 1.9 1.0 1 0 0 1 1 1 1 Multiprotein bridging factor 1 Peptidase_C12 PF01088.21 KXH47259.1 - 4.7e-66 222.5 0.0 7.7e-66 221.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Xan_ur_permease PF00860.20 KXH47259.1 - 8.7e-26 90.5 24.9 9.6e-25 87.1 23.1 2.8 2 1 0 2 2 2 1 Permease family UCH_C PF18031.1 KXH47259.1 - 1.7e-10 40.6 0.2 3.2e-10 39.7 0.2 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases MFS_MOT1 PF16983.5 KXH47259.1 - 0.0022 18.3 2.3 0.0022 18.3 2.3 3.1 3 0 0 3 3 3 1 Molybdate transporter of MFS superfamily GCD14 PF08704.10 KXH47263.1 - 0.09 12.4 0.0 4.7 6.8 0.0 2.4 2 0 0 2 2 2 0 tRNA methyltransferase complex GCD14 subunit PAC4 PF16093.5 KXH47264.1 - 5.4e-21 74.6 0.1 7.4e-21 74.1 0.1 1.2 1 0 0 1 1 1 1 Proteasome assembly chaperone 4 POC3_POC4 PF10448.9 KXH47264.1 - 0.11 12.5 0.0 0.14 12.2 0.0 1.3 1 1 0 1 1 1 0 20S proteasome chaperone assembly proteins 3 and 4 HEAT_EZ PF13513.6 KXH47265.1 - 1.1e-28 99.3 10.9 1.8e-14 53.9 0.0 11.2 12 1 0 12 12 12 3 HEAT-like repeat HEAT PF02985.22 KXH47265.1 - 1.4e-27 93.4 6.9 5e-05 23.2 0.0 10.5 11 0 0 11 11 10 6 HEAT repeat HEAT_2 PF13646.6 KXH47265.1 - 1.2e-18 67.2 2.1 8.5e-06 26.1 0.0 8.0 5 3 5 10 10 10 3 HEAT repeats Cnd1 PF12717.7 KXH47265.1 - 7.4e-12 45.6 0.4 0.0055 16.8 0.0 5.5 4 1 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 KXH47265.1 - 2.3e-10 40.9 0.0 0.0017 18.9 0.0 6.0 5 2 1 6 6 5 1 Vacuolar 14 Fab1-binding region MMS19_C PF12460.8 KXH47265.1 - 4e-08 32.8 2.5 0.41 9.7 0.0 5.1 5 0 0 5 5 5 3 RNAPII transcription regulator C-terminal CLASP_N PF12348.8 KXH47265.1 - 2.6e-07 30.5 0.0 1.6 8.3 0.0 6.4 4 2 2 7 7 7 1 CLASP N terminal IBN_N PF03810.19 KXH47265.1 - 3.3e-07 30.1 1.1 7.3e-06 25.8 0.0 4.1 4 1 0 4 4 3 1 Importin-beta N-terminal domain Adaptin_N PF01602.20 KXH47265.1 - 0.00012 20.7 0.3 0.63 8.5 0.0 3.3 2 2 0 2 2 2 2 Adaptin N terminal region Arm PF00514.23 KXH47265.1 - 0.00066 19.6 3.6 8.4 6.6 0.0 6.1 5 1 1 6 6 6 2 Armadillo/beta-catenin-like repeat HEAT_PBS PF03130.16 KXH47265.1 - 0.0015 19.0 3.9 23 6.1 0.0 5.8 6 0 0 6 6 4 0 PBS lyase HEAT-like repeat RTP1_C1 PF10363.9 KXH47265.1 - 0.0044 17.2 0.2 0.17 12.1 0.0 3.6 4 0 0 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 DUF3437 PF11919.8 KXH47265.1 - 0.0056 16.6 0.1 7.3 6.6 0.0 4.1 3 0 0 3 3 3 1 Domain of unknown function (DUF3437) Gcn1_N PF12074.8 KXH47265.1 - 0.011 15.1 0.1 3.6 6.8 0.0 3.2 3 0 0 3 3 3 0 Generalcontrol nonderepressible 1 (Gcn1) N-terminal Glyco_hydro_10 PF00331.20 KXH47265.1 - 0.049 12.8 0.0 0.094 11.8 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 10 BP28CT PF08146.12 KXH47265.1 - 0.084 12.7 0.0 0.82 9.5 0.0 2.6 3 0 0 3 3 3 0 BP28CT (NUC211) domain Drf_GBD PF06371.13 KXH47270.1 - 2.4e-64 216.4 0.0 5.7e-64 215.1 0.0 1.7 1 0 0 1 1 1 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 KXH47270.1 - 2.1e-53 180.9 2.7 7.7e-53 179.0 2.1 2.1 1 1 1 2 2 2 1 Diaphanous FH3 Domain Bap31_Bap29_C PF18035.1 KXH47270.1 - 2.8 8.0 5.6 9.8 6.3 5.6 1.9 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain zf-RING_2 PF13639.6 KXH47271.1 - 8.6e-08 32.4 5.7 8.6e-08 32.4 5.7 2.7 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.25 KXH47271.1 - 1.9e-05 24.4 0.6 1.9e-05 24.4 0.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KXH47271.1 - 0.00011 21.8 0.2 0.00084 19.0 0.0 2.5 2 1 0 2 2 2 1 RING-like zinc finger zf-rbx1 PF12678.7 KXH47271.1 - 0.00023 21.4 5.9 0.00023 21.4 5.9 2.8 3 0 0 3 3 3 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KXH47271.1 - 0.00054 19.9 0.0 0.00054 19.9 0.0 2.6 2 1 1 3 3 3 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KXH47271.1 - 0.00056 19.7 6.8 0.0019 18.0 3.4 3.1 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KXH47271.1 - 0.0051 16.8 4.7 0.0051 16.8 4.7 2.3 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 KXH47271.1 - 0.014 15.3 7.7 0.026 14.5 2.9 2.5 2 0 0 2 2 2 0 zinc-RING finger domain Prok-RING_4 PF14447.6 KXH47271.1 - 0.15 11.9 6.0 0.071 13.0 1.8 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 NDUF_B12 PF08122.12 KXH47271.1 - 7.1 6.8 7.5 13 5.9 3.0 3.1 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase B12 subunit family Hus1 PF04005.12 KXH47272.1 - 1.6e-88 296.6 0.0 1.8e-88 296.4 0.0 1.0 1 0 0 1 1 1 1 Hus1-like protein MMtag PF10159.9 KXH47273.1 - 1e-30 105.8 3.6 1e-30 105.8 3.6 2.7 2 1 0 2 2 2 1 Multiple myeloma tumor-associated Med6 PF04934.14 KXH47274.1 - 1.6e-36 125.0 0.0 2.4e-36 124.5 0.0 1.2 1 0 0 1 1 1 1 MED6 mediator sub complex component HET PF06985.11 KXH47315.1 - 2e-11 44.4 5.2 3.1e-09 37.3 0.9 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) F-box-like PF12937.7 KXH47316.1 - 2.8e-06 27.1 0.0 6.7e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXH47316.1 - 6.4e-06 25.9 0.1 2.8e-05 23.9 0.0 2.1 2 0 0 2 2 2 1 F-box domain MFS_1 PF07690.16 KXH47317.1 - 1.5e-14 53.7 33.6 2.7e-09 36.4 20.0 3.0 2 1 1 3 3 3 2 Major Facilitator Superfamily Nodulin-like PF06813.13 KXH47317.1 - 3.6e-05 23.4 9.1 0.021 14.3 0.1 3.0 3 1 1 4 4 4 2 Nodulin-like DUF4271 PF14093.6 KXH47317.1 - 0.76 9.6 0.0 0.76 9.6 0.0 3.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4271) Pkinase PF00069.25 KXH47320.1 - 2e-22 79.8 0.0 7.1e-22 78.0 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXH47320.1 - 6.5e-11 42.0 0.0 1.3e-09 37.8 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Phage_int_SAM_1 PF02899.17 KXH47320.1 - 0.093 13.0 0.0 0.3 11.4 0.0 1.8 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain zf-met PF12874.7 KXH47320.1 - 0.098 13.1 0.3 0.36 11.3 0.3 2.1 1 0 0 1 1 1 0 Zinc-finger of C2H2 type Pyr_redox_2 PF07992.14 KXH47322.1 - 2.3e-07 30.3 0.1 1.4e-05 24.5 0.0 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXH47322.1 - 1.7e-06 27.4 0.0 7.4e-06 25.3 0.0 1.9 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.19 KXH47322.1 - 2.7e-05 22.8 0.0 0.0012 17.4 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KXH47322.1 - 0.0014 18.8 0.2 0.0039 17.4 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KXH47322.1 - 0.0016 17.7 0.0 0.028 13.7 0.1 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 KXH47322.1 - 0.063 13.3 0.0 1.3 9.1 0.0 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Myofilin PF15929.5 KXH47323.1 - 0.055 13.9 0.1 0.24 11.8 0.0 1.9 1 1 0 2 2 2 0 Myofilin Methyltransf_25 PF13649.6 KXH47325.1 - 2.9e-14 53.6 0.0 4.8e-14 52.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH47325.1 - 1.9e-13 50.9 0.1 3.1e-13 50.2 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXH47325.1 - 1.1e-10 41.6 0.0 1.4e-10 41.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH47325.1 - 1.6e-08 35.2 0.0 2.6e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH47325.1 - 3.2e-08 33.5 0.0 4.9e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KXH47325.1 - 1.6e-06 27.7 0.1 2.2e-06 27.3 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KXH47325.1 - 3.6e-05 23.4 0.0 4.6e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain MetW PF07021.12 KXH47325.1 - 0.00022 20.9 0.0 0.00035 20.2 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Ubie_methyltran PF01209.18 KXH47325.1 - 0.00041 19.8 0.1 0.00075 18.9 0.1 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 KXH47325.1 - 0.00059 19.2 0.1 0.00088 18.7 0.1 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase ADH_zinc_N PF00107.26 KXH47325.1 - 0.0044 17.0 0.1 0.017 15.1 0.1 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase TPMT PF05724.11 KXH47325.1 - 0.0064 16.2 0.0 0.0097 15.6 0.0 1.2 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_16 PF10294.9 KXH47325.1 - 0.011 15.4 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_32 PF13679.6 KXH47325.1 - 0.053 13.5 0.0 0.083 12.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.14 KXH47325.1 - 0.081 12.3 0.3 0.15 11.4 0.0 1.7 2 1 0 2 2 2 0 Tellurite resistance protein TehB Methyltransf_18 PF12847.7 KXH47325.1 - 0.12 12.3 0.1 0.19 11.7 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase domain Mito_carr PF00153.27 KXH47440.1 - 2.7e-71 235.6 3.5 8.5e-24 83.3 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KXH47440.1 - 0.087 12.0 5.5 7.1 5.7 0.1 3.8 1 1 4 5 5 5 0 Gammaproteobacterial serine protease Zn_clus PF00172.18 KXH47441.1 - 0.011 15.8 10.6 0.019 15.1 10.6 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain But2 PF09792.9 KXH47455.1 - 0.033 14.6 0.0 0.047 14.1 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin 3 binding protein But2 C-terminal domain Meth_synt_2 PF01717.18 KXH47457.1 - 3.2e-150 499.9 0.0 4.7e-144 479.6 0.0 2.3 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 KXH47457.1 - 6.3e-121 403.7 0.0 4.8e-113 377.8 0.0 3.6 3 1 1 4 4 4 2 Cobalamin-independent synthase, N-terminal domain URO-D PF01208.17 KXH47457.1 - 1.5e-05 24.3 0.0 0.0028 16.9 0.0 2.5 2 0 0 2 2 2 2 Uroporphyrinogen decarboxylase (URO-D) DUF3018 PF11455.8 KXH47457.1 - 0.12 12.3 0.2 0.61 10.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3018) VbhA PF18495.1 KXH47457.1 - 0.14 12.0 0.0 18 5.3 0.0 2.9 2 0 0 2 2 2 0 Antitoxin VbhA Oxidored_FMN PF00724.20 KXH47458.1 - 3.9e-65 220.4 0.0 1.4e-61 208.7 0.0 2.1 1 1 1 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family OCD_Mu_crystall PF02423.15 KXH47459.1 - 5.2e-17 61.8 0.0 2.6e-14 52.9 0.0 2.9 1 1 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.20 KXH47459.1 - 9.9e-08 32.1 0.1 0.00013 22.0 0.1 2.3 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase p450 PF00067.22 KXH47460.1 - 5.8e-69 233.0 0.0 6.9e-69 232.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_23 PF13489.6 KXH47461.1 - 4.4e-21 75.4 0.0 6.8e-21 74.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH47461.1 - 1.1e-11 45.3 0.0 2e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH47461.1 - 6.4e-11 42.3 0.0 4.1e-10 39.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH47461.1 - 1.1e-09 39.0 0.0 4.5e-09 36.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH47461.1 - 2e-08 34.7 0.0 3.4e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 KXH47461.1 - 0.0096 15.2 0.0 0.035 13.4 0.0 2.0 2 1 0 2 2 2 1 O-methyltransferase domain Methyltransf_4 PF02390.17 KXH47461.1 - 0.02 14.4 0.0 0.045 13.2 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase MTS PF05175.14 KXH47461.1 - 0.02 14.4 0.0 0.032 13.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Ubie_methyltran PF01209.18 KXH47461.1 - 0.043 13.1 0.0 0.72 9.1 0.0 2.6 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family CMAS PF02353.20 KXH47461.1 - 0.052 12.8 0.0 0.12 11.7 0.0 1.5 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase FtsJ PF01728.19 KXH47461.1 - 0.066 13.3 0.0 0.099 12.7 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase SURF4 PF02077.15 KXH47462.1 - 2.2e-97 325.8 8.6 2.5e-97 325.7 8.6 1.0 1 0 0 1 1 1 1 SURF4 family HeLo PF14479.6 KXH47463.1 - 7.4e-41 140.3 0.1 8.8e-40 136.7 0.0 2.6 2 1 0 2 2 2 1 Prion-inhibition and propagation Pkinase_Tyr PF07714.17 KXH47463.1 - 0.15 11.3 0.0 1.2 8.3 0.0 2.0 2 0 0 2 2 2 0 Protein tyrosine kinase RRM_1 PF00076.22 KXH47464.1 - 5.1e-18 64.7 0.1 9.9e-18 63.7 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KXH47464.1 - 0.00067 19.2 0.0 0.001 18.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KXH47464.1 - 0.071 13.0 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif DPCD PF14913.6 KXH47464.1 - 0.1 11.9 0.1 0.15 11.4 0.1 1.2 1 0 0 1 1 1 0 DPCD protein family Peptidase_C15 PF01470.17 KXH47466.1 - 1.7e-13 51.2 0.0 1.1e-06 29.0 0.0 2.8 2 1 0 2 2 2 2 Pyroglutamyl peptidase Hamartin PF04388.12 KXH47468.1 - 4.1 6.0 11.1 4.5 5.8 11.1 1.1 1 0 0 1 1 1 0 Hamartin protein VRR_NUC PF08774.11 KXH47469.1 - 1.4e-22 79.8 0.0 4.6e-22 78.1 0.0 1.9 1 0 0 1 1 1 1 VRR-NUC domain Dpy-30 PF05186.13 KXH47470.1 - 2.5e-11 43.1 0.0 3.6e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 Dpy-30 motif Ribosomal_S13_N PF08069.12 KXH47471.1 - 1.2e-30 105.3 0.1 2.1e-30 104.5 0.1 1.4 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 KXH47471.1 - 3.2e-15 56.1 0.1 5e-15 55.5 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.18 KXH47471.1 - 0.027 14.4 0.2 0.066 13.1 0.1 1.7 2 0 0 2 2 2 0 'Paired box' domain HOIP-UBA PF16678.5 KXH47471.1 - 0.073 13.1 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 HOIP UBA domain pair RRM_1 PF00076.22 KXH47472.1 - 4.4e-32 109.7 2.0 5.2e-13 48.6 0.0 4.1 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KXH47472.1 - 2.9e-05 23.8 0.0 0.18 11.7 0.0 3.2 3 0 0 3 3 3 2 Occluded RNA-recognition motif RRM_Rrp7 PF17799.1 KXH47472.1 - 0.014 15.2 0.1 0.044 13.6 0.1 1.8 2 0 0 2 2 2 0 Rrp7 RRM-like N-terminal domain TcpA PF05946.12 KXH47472.1 - 0.03 14.4 0.7 1.9 8.6 0.0 2.5 2 1 0 2 2 2 0 Toxin-coregulated pilus subunit TcpA Fungal_trans PF04082.18 KXH47474.1 - 9.7e-07 28.1 0.2 6.9e-06 25.3 0.2 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH47474.1 - 0.00034 20.7 9.6 0.00085 19.4 9.6 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_3_C PF01915.22 KXH47475.1 - 5e-63 212.7 0.0 1.5e-62 211.2 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KXH47475.1 - 3.3e-47 161.4 0.0 5.1e-47 160.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KXH47475.1 - 1.6e-21 76.1 0.1 8.1e-21 73.9 0.1 2.3 3 0 0 3 3 3 1 Fibronectin type III-like domain PA14 PF07691.12 KXH47475.1 - 2.8e-09 36.9 0.0 5.9e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 PA14 domain Phage_tail_X PF05489.12 KXH47475.1 - 0.17 11.5 0.2 0.44 10.3 0.2 1.6 1 0 0 1 1 1 0 Phage Tail Protein X DUF11 PF01345.18 KXH47475.1 - 0.22 11.9 6.8 0.2 12.0 4.4 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF11 Sugar_tr PF00083.24 KXH47476.1 - 3.2e-71 240.5 29.2 4.1e-71 240.2 29.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH47476.1 - 2.4e-16 59.6 30.3 2.4e-16 59.6 30.3 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily HET PF06985.11 KXH47476.1 - 6.7e-10 39.5 5.6 1e-07 32.4 0.3 3.1 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) Abhydrolase_6 PF12697.7 KXH47477.1 - 1.1e-11 45.8 2.0 1.3e-11 45.5 2.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXH47477.1 - 0.029 13.6 0.0 0.042 13.1 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 KXH47477.1 - 0.13 12.1 0.0 0.94 9.3 0.0 2.1 2 0 0 2 2 2 0 Serine hydrolase DUF4190 PF13828.6 KXH47478.1 - 0.81 9.5 11.5 4.6 7.1 0.9 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF4190) Peptidase_S8 PF00082.22 KXH47480.1 - 3.3e-43 148.1 0.0 2.9e-42 145.0 0.0 2.1 1 1 0 1 1 1 1 Subtilase family fn3_6 PF17766.1 KXH47480.1 - 8.3e-21 74.0 0.0 1.5e-20 73.2 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type-III domain Inhibitor_I9 PF05922.16 KXH47480.1 - 2.1e-11 44.3 0.0 3.9e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 PA PF02225.22 KXH47480.1 - 1.6e-09 37.6 1.5 4.8e-09 36.1 1.5 1.8 1 0 0 1 1 1 1 PA domain Cu-oxidase_3 PF07732.15 KXH47481.1 - 8.3e-46 154.9 6.3 4.8e-45 152.4 0.8 3.4 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.22 KXH47481.1 - 4.8e-30 104.8 0.7 1.8e-28 99.7 0.0 3.1 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KXH47481.1 - 1.4e-28 99.3 9.8 3.9e-24 84.9 0.2 4.1 4 0 0 4 4 4 3 Multicopper oxidase Cupredoxin_1 PF13473.6 KXH47481.1 - 0.0083 16.2 0.0 15 5.7 0.0 3.9 3 1 1 4 4 4 1 Cupredoxin-like domain DUF2615 PF11027.8 KXH47481.1 - 0.053 13.7 0.0 0.15 12.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2615) CAP_N PF01213.19 KXH47481.1 - 5.8 6.3 10.1 15 5.0 10.1 1.6 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Beta-lactamase PF00144.24 KXH47482.1 - 1.6e-63 215.0 0.0 2e-63 214.7 0.0 1.0 1 0 0 1 1 1 1 Beta-lactamase Tyrosinase PF00264.20 KXH47483.1 - 7.5e-54 183.3 0.0 1.3e-53 182.6 0.0 1.4 1 0 0 1 1 1 1 Common central domain of tyrosinase FAD_binding_3 PF01494.19 KXH47484.1 - 3.9e-24 85.5 0.0 5.2e-24 85.1 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KXH47484.1 - 5.2e-08 32.5 0.1 0.0076 15.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXH47484.1 - 2.2e-07 30.8 0.1 0.00042 20.0 0.0 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXH47484.1 - 4e-05 23.7 0.0 0.00025 21.2 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KXH47484.1 - 0.00082 19.9 0.1 0.063 13.8 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KXH47484.1 - 0.0013 17.7 0.3 0.21 10.4 0.1 2.4 1 1 1 2 2 2 2 Tryptophan halogenase FAD_binding_2 PF00890.24 KXH47484.1 - 0.0062 15.7 0.1 0.019 14.1 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain CoA_transf_3 PF02515.17 KXH47484.1 - 0.009 15.2 0.0 0.014 14.5 0.0 1.3 1 0 0 1 1 1 1 CoA-transferase family III HI0933_like PF03486.14 KXH47484.1 - 0.038 12.7 0.0 2.8 6.6 0.0 2.8 2 1 0 3 3 3 0 HI0933-like protein AlaDh_PNT_C PF01262.21 KXH47484.1 - 0.085 12.1 0.1 0.29 10.4 0.0 1.9 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 KXH47484.1 - 0.11 11.8 0.0 0.2 11.0 0.0 1.4 1 1 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.22 KXH47484.1 - 0.11 11.6 0.3 0.24 10.4 0.3 1.7 1 1 0 1 1 1 0 Glucose inhibited division protein A ApbA PF02558.16 KXH47484.1 - 0.2 11.3 0.1 0.35 10.5 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Acetyltransf_3 PF13302.7 KXH47485.1 - 2.2e-15 57.6 0.0 4.1e-15 56.7 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXH47485.1 - 6.2e-05 23.2 0.2 0.00013 22.2 0.2 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 KXH47485.1 - 0.13 11.9 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Egh16-like PF11327.8 KXH47486.1 - 2e-27 96.8 8.8 2e-27 96.8 8.8 2.1 2 1 0 2 2 2 1 Egh16-like virulence factor Izumo-Ig PF16706.5 KXH47486.1 - 0.016 15.2 0.0 0.03 14.4 0.0 1.4 1 0 0 1 1 1 0 Izumo-like Immunoglobulin domain V-set PF07686.17 KXH47486.1 - 0.019 15.1 0.4 0.047 13.9 0.1 1.9 2 0 0 2 2 2 0 Immunoglobulin V-set domain DUF4307 PF14155.6 KXH47486.1 - 0.08 12.8 1.8 0.097 12.5 0.2 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4307) HET PF06985.11 KXH47487.1 - 5.9e-06 26.7 0.4 9.1e-06 26.1 0.4 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) APH PF01636.23 KXH47488.1 - 4.3e-42 144.7 0.0 6.4e-42 144.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 KXH47488.1 - 4.4e-06 26.2 0.0 6.4e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase Kdo PF06293.14 KXH47488.1 - 0.0002 20.8 0.1 0.00056 19.3 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Fructosamin_kin PF03881.14 KXH47488.1 - 0.00028 20.2 0.0 0.00082 18.7 0.0 1.7 1 1 0 1 1 1 1 Fructosamine kinase Choline_kinase PF01633.20 KXH47488.1 - 0.0019 17.8 0.0 0.0029 17.2 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 KXH47488.1 - 0.013 15.1 0.0 0.14 11.8 0.0 2.0 2 0 0 2 2 2 0 RIO1 family DUF1679 PF07914.11 KXH47488.1 - 0.015 14.2 0.0 0.047 12.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) CBFB_NFYA PF02045.15 KXH47489.1 - 9.8e-29 99.8 4.6 2.3e-28 98.6 4.6 1.7 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Hus1 PF04005.12 KXH47489.1 - 0.056 12.5 0.1 0.1 11.7 0.1 1.3 1 0 0 1 1 1 0 Hus1-like protein TFIIA PF03153.13 KXH47489.1 - 0.11 12.4 19.0 0.15 12.1 19.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit NAD_binding_8 PF13450.6 KXH47490.1 - 4.8e-09 36.3 0.1 1.1e-08 35.2 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KXH47490.1 - 5.4e-08 32.6 0.1 1.1e-07 31.6 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KXH47490.1 - 4.9e-07 29.2 3.8 4.9e-07 29.2 3.8 1.5 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 KXH47490.1 - 7.6e-07 28.7 0.1 1.4e-06 27.8 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXH47490.1 - 1.8e-06 27.8 0.1 4.9e-06 26.4 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 KXH47490.1 - 2.6e-06 27.0 0.0 0.0016 17.8 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 KXH47490.1 - 3.5e-06 26.5 0.5 6.4e-06 25.6 0.5 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXH47490.1 - 5.4e-06 25.4 3.3 8.1e-06 24.8 3.3 1.2 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.17 KXH47490.1 - 2.8e-05 23.5 0.7 5e-05 22.7 0.7 1.3 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.22 KXH47490.1 - 3.2e-05 23.2 0.2 4.5e-05 22.7 0.2 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 KXH47490.1 - 4.1e-05 23.0 0.0 6.4e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 KXH47490.1 - 9.9e-05 22.8 0.5 0.00036 21.0 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KXH47490.1 - 0.014 14.7 0.2 0.014 14.7 0.2 1.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 KXH47490.1 - 0.017 15.6 0.0 0.035 14.5 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Trp_halogenase PF04820.14 KXH47490.1 - 0.017 14.0 0.4 0.027 13.4 0.4 1.2 1 0 0 1 1 1 0 Tryptophan halogenase IlvN PF07991.12 KXH47490.1 - 0.037 13.6 0.7 0.12 11.9 0.7 1.8 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Lycopene_cycl PF05834.12 KXH47490.1 - 0.08 12.0 0.5 0.12 11.4 0.5 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein MFS_1 PF07690.16 KXH47491.1 - 8.6e-14 51.2 32.4 8.6e-14 51.2 32.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.16 KXH47491.1 - 0.00026 20.7 3.6 0.00081 19.1 3.6 1.9 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 Tyrosinase PF00264.20 KXH47492.1 - 8.1e-53 180.0 0.6 1.2e-52 179.4 0.6 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase DUF423 PF04241.15 KXH47493.1 - 1.7 8.9 5.2 1.3 9.3 1.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF423) adh_short PF00106.25 KXH47494.1 - 2.5e-34 118.5 0.0 5e-34 117.5 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXH47494.1 - 1.5e-22 80.3 0.1 2.3e-22 79.7 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH47494.1 - 2.7e-08 33.9 0.1 3.7e-08 33.5 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXH47494.1 - 0.0085 15.6 0.0 0.01 15.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 KXH47494.1 - 0.074 12.4 0.0 0.16 11.3 0.0 1.4 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) SET PF00856.28 KXH47495.1 - 2.9e-13 50.5 0.1 1e-12 48.8 0.1 1.8 1 1 0 1 1 1 1 SET domain Metallophos PF00149.28 KXH47496.1 - 1.7e-09 38.5 0.1 2.6e-09 37.9 0.1 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KXH47496.1 - 4.8e-07 30.1 0.0 9.8e-06 25.9 0.0 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain AbiEii PF08843.11 KXH47497.1 - 0.0089 16.0 0.0 0.013 15.5 0.0 1.5 1 1 0 1 1 1 1 Nucleotidyl transferase AbiEii toxin, Type IV TA system DUF1907 PF08925.11 KXH47499.1 - 5.5e-109 364.0 0.0 6.2e-109 363.8 0.0 1.0 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1907) F-box-like PF12937.7 KXH47500.1 - 7.7e-05 22.5 0.4 0.00028 20.7 0.4 2.1 1 0 0 1 1 1 1 F-box-like Mad3_BUB1_I PF08311.12 KXH47501.1 - 4.3e-43 146.2 0.4 1e-42 145.0 0.4 1.6 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Mad3_BUB1_II PF08171.11 KXH47501.1 - 4e-08 33.3 0.0 2.4e-07 30.8 0.0 2.3 2 0 0 2 2 2 1 Mad3/BUB1 homology region 2 Pkinase PF00069.25 KXH47501.1 - 2.6e-07 30.3 0.0 1.6e-06 27.7 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXH47501.1 - 0.024 13.9 0.0 0.11 11.7 0.0 1.9 1 1 0 1 1 1 0 Protein tyrosine kinase Mad3_BUB1_I_2 PF17014.5 KXH47501.1 - 0.055 13.6 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Putative Mad3/BUB1 like region 1 protein Kinase-like PF14531.6 KXH47501.1 - 0.2 11.0 0.0 0.36 10.1 0.0 1.3 1 0 0 1 1 1 0 Kinase-like AP_endonuc_2 PF01261.24 KXH47502.1 - 4.8e-35 120.9 0.3 6.9e-35 120.4 0.3 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel DUF2124 PF09897.9 KXH47502.1 - 0.014 15.3 0.0 0.033 14.1 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2124) DAGAT PF03982.13 KXH47503.1 - 1e-93 313.5 0.0 1.4e-93 313.1 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase DUF4110 PF13422.6 KXH47504.1 - 2.9e-30 104.2 1.5 2.9e-30 104.2 1.5 3.7 4 0 0 4 4 4 1 Domain of unknown function (DUF4110) Kelch_4 PF13418.6 KXH47504.1 - 2e-20 72.5 14.9 3.9e-06 26.8 0.0 6.7 7 1 0 7 7 7 4 Galactose oxidase, central domain Kelch_3 PF13415.6 KXH47504.1 - 3.2e-20 71.9 10.3 2.6e-07 30.7 0.0 5.4 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.6 KXH47504.1 - 1.5e-18 66.3 1.9 1.4e-07 31.3 0.0 5.5 6 0 0 6 6 6 3 Kelch motif Kelch_2 PF07646.15 KXH47504.1 - 2.9e-14 52.4 4.0 0.0019 18.1 0.0 5.9 5 1 0 5 5 5 3 Kelch motif Kelch_6 PF13964.6 KXH47504.1 - 9.2e-13 48.0 1.0 0.00011 22.3 0.1 5.0 5 0 0 5 5 5 2 Kelch motif Kelch_1 PF01344.25 KXH47504.1 - 1.2e-10 40.8 0.6 0.00054 19.5 0.0 4.9 4 1 0 4 4 4 3 Kelch motif PI3K_1B_p101 PF10486.9 KXH47504.1 - 0.67 7.7 7.6 1.2 6.8 7.6 1.3 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit BUD22 PF09073.10 KXH47504.1 - 9.8 5.4 36.0 0.076 12.3 19.2 2.3 2 0 0 2 2 2 0 BUD22 WLM PF08325.10 KXH47505.1 - 4e-26 92.3 0.6 1.3e-25 90.7 0.6 1.9 1 1 0 1 1 1 1 WLM domain DUF45 PF01863.17 KXH47505.1 - 2e-07 31.3 0.3 2e-07 31.3 0.3 2.1 3 0 0 3 3 3 1 Protein of unknown function DUF45 Zf_RING PF16744.5 KXH47505.1 - 0.24 11.5 1.6 0.69 10.1 1.6 1.8 1 0 0 1 1 1 0 KIAA1045 RING finger zf-RanBP PF00641.18 KXH47505.1 - 0.66 9.3 2.6 2 7.8 2.6 1.8 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others SOG2 PF10428.9 KXH47505.1 - 0.73 9.0 8.5 1.1 8.4 8.5 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Zn_ribbon_17 PF17120.5 KXH47505.1 - 3 7.5 7.7 8.5 6.1 7.7 1.8 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type RRM_1 PF00076.22 KXH47524.1 - 2.6e-22 78.4 0.0 3.4e-22 78.1 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KXH47524.1 - 0.0024 17.9 0.0 0.0045 17.1 0.0 1.4 1 1 0 1 1 1 1 RNA recognition motif RRM_occluded PF16842.5 KXH47524.1 - 0.046 13.6 0.0 0.062 13.2 0.0 1.2 1 0 0 1 1 1 0 Occluded RNA-recognition motif PAP_PilO PF06864.12 KXH47524.1 - 0.067 12.0 0.1 0.083 11.7 0.1 1.1 1 0 0 1 1 1 0 Pilin accessory protein (PilO) DUF2076 PF09849.9 KXH47524.1 - 5.2 7.0 10.1 7.1 6.6 10.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) ChaC PF04752.12 KXH47525.1 - 2.2e-37 128.9 0.0 2.9e-37 128.5 0.0 1.1 1 0 0 1 1 1 1 ChaC-like protein EF-hand_1 PF00036.32 KXH47526.1 - 1.7e-25 86.6 4.7 5.4e-06 25.6 0.0 5.4 5 0 0 5 5 5 5 EF hand EF-hand_7 PF13499.6 KXH47526.1 - 1.2e-21 76.9 2.3 3.3e-09 37.1 0.0 3.5 3 1 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 KXH47526.1 - 9.2e-21 72.0 4.4 0.0022 17.8 0.1 5.3 5 0 0 5 5 5 5 EF-hand domain EF-hand_8 PF13833.6 KXH47526.1 - 6.8e-18 64.3 7.5 3.5e-09 36.4 0.0 4.9 3 2 2 5 5 5 5 EF-hand domain pair EF-hand_5 PF13202.6 KXH47526.1 - 5.8e-16 57.2 2.0 0.0021 17.5 0.1 4.5 4 0 0 4 4 4 4 EF hand SPX PF03105.19 KXH47526.1 - 0.14 12.1 1.8 0.16 11.9 1.8 1.1 1 0 0 1 1 1 0 SPX domain Lactamase_B_3 PF13483.6 KXH47527.1 - 3e-07 30.5 0.4 3.6e-06 26.9 0.0 2.6 3 0 0 3 3 3 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 KXH47527.1 - 0.00018 21.1 0.0 0.00032 20.3 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Hep_59 PF07052.11 KXH47529.1 - 1.5e-10 41.8 1.4 6e-10 39.8 0.0 2.3 2 1 0 2 2 2 1 Hepatocellular carcinoma-associated antigen 59 FAM193_C PF15914.5 KXH47529.1 - 0.3 10.9 1.9 0.31 10.8 0.4 1.8 2 0 0 2 2 2 0 FAM193 family C-terminal Metallophos PF00149.28 KXH47530.1 - 4.1e-40 138.5 0.1 5.3e-40 138.1 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KXH47530.1 - 3.2e-23 81.9 1.8 4.7e-23 81.4 1.0 1.7 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain Rdx PF10262.9 KXH47531.1 - 1.3e-25 89.3 0.0 7.5e-25 86.9 0.0 2.0 1 1 0 1 1 1 1 Rdx family Macoilin PF09726.9 KXH47531.1 - 1.5 7.2 3.9 1.8 7.0 3.9 1.0 1 0 0 1 1 1 0 Macoilin family NUDE_C PF04880.13 KXH47531.1 - 6.8 7.1 13.8 16 6.0 13.8 1.6 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region Pro_CA PF00484.19 KXH47533.1 - 0.00027 21.2 0.0 0.00035 20.9 0.0 1.2 1 0 0 1 1 1 1 Carbonic anhydrase DNAPolymera_Pol PF11590.8 KXH47533.1 - 0.047 13.6 1.2 0.087 12.7 1.3 1.5 1 1 0 1 1 1 0 DNA polymerase catalytic subunit Pol NTF2 PF02136.20 KXH47534.1 - 1.5e-29 103.0 0.2 1.6e-29 102.9 0.2 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Big_9 PF17963.1 KXH47535.1 - 0.013 16.2 0.3 0.013 16.2 0.3 3.0 2 1 0 2 2 2 0 Bacterial Ig domain Acetyltransf_1 PF00583.25 KXH47536.1 - 2.1e-06 27.9 0.0 2.5e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXH47536.1 - 2.4e-05 24.6 0.0 3.4e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KXH47536.1 - 2.7e-05 24.1 0.0 4e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain EF-hand_4 PF12763.7 KXH47537.1 - 0.01 15.7 0.0 0.021 14.8 0.0 1.4 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand MAP65_ASE1 PF03999.12 KXH47538.1 - 2.5e-73 247.8 23.4 6.6e-73 246.4 23.3 1.7 1 1 1 2 2 2 1 Microtubule associated protein (MAP65/ASE1 family) Spectrin PF00435.21 KXH47538.1 - 0.0044 17.5 2.0 0.0044 17.5 2.0 4.1 3 1 0 3 3 3 1 Spectrin repeat BAR_3 PF16746.5 KXH47538.1 - 0.2 11.3 8.0 0.52 10.0 2.4 2.6 2 0 0 2 2 2 0 BAR domain of APPL family Baculo_PEP_C PF04513.12 KXH47538.1 - 0.32 11.0 2.4 2.9 7.9 0.6 2.9 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_13 PF13166.6 KXH47538.1 - 2.9 6.4 10.9 0.14 10.8 5.0 1.6 2 0 0 2 2 2 0 AAA domain DUF4407 PF14362.6 KXH47538.1 - 3.4 7.0 10.9 0.56 9.5 3.9 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) Polysacc_lyase PF14099.6 KXH47539.1 - 2.9e-51 174.3 7.1 3.5e-51 174.1 7.1 1.0 1 0 0 1 1 1 1 Polysaccharide lyase MFS_1 PF07690.16 KXH47540.1 - 5.5e-32 111.1 58.1 7.1e-17 61.3 22.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KXH47540.1 - 8e-07 27.9 16.2 8e-07 27.9 16.2 3.3 1 1 3 4 4 4 2 MFS/sugar transport protein MFS_1_like PF12832.7 KXH47540.1 - 0.00034 19.6 0.9 0.00034 19.6 0.9 2.4 2 1 0 2 2 2 1 MFS_1 like family Chlam_vir PF05475.11 KXH47540.1 - 0.0048 16.7 3.5 0.058 13.1 0.3 3.1 2 1 1 3 3 3 1 Pgp3 C-terminal domain CCB1 PF12046.8 KXH47540.1 - 9.3 5.6 6.9 0.96 8.8 0.7 2.5 3 0 0 3 3 3 0 Cofactor assembly of complex C subunit B UDPG_MGDP_dh_N PF03721.14 KXH47541.1 - 9.9e-20 70.9 0.1 2.7e-17 63.0 0.1 2.3 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.19 KXH47541.1 - 2.7e-19 69.2 0.0 5.7e-19 68.1 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain NAD_binding_2 PF03446.15 KXH47541.1 - 3.2e-06 27.4 0.0 5.6e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase TrkA_N PF02254.18 KXH47541.1 - 0.0012 19.1 0.0 0.0037 17.5 0.0 1.9 2 0 0 2 2 2 1 TrkA-N domain UDPG_MGDP_dh_C PF03720.15 KXH47541.1 - 0.0028 18.1 0.0 0.0063 16.9 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain F420_oxidored PF03807.17 KXH47541.1 - 0.015 15.8 0.0 0.65 10.6 0.0 3.0 2 1 1 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent Methyltransf_25 PF13649.6 KXH47541.1 - 0.031 15.0 0.0 0.12 13.1 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain 3HCDH_N PF02737.18 KXH47541.1 - 0.086 12.7 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Chitin_synth_2 PF03142.15 KXH47542.1 - 2.3e-27 95.8 0.1 4.5e-23 81.7 0.1 2.3 1 1 0 2 2 2 2 Chitin synthase Glyco_tranf_2_3 PF13641.6 KXH47542.1 - 1.8e-10 41.1 0.1 3.1e-10 40.3 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 KXH47542.1 - 1.2e-09 38.4 1.3 2.5e-09 37.4 1.3 1.6 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 KXH47542.1 - 1.9e-05 24.5 0.0 0.097 12.5 0.0 3.0 2 1 0 2 2 2 2 Glycosyl transferase family 2 Pur_ac_phosph_N PF16656.5 KXH47544.1 - 1.1 9.9 6.7 0.38 11.4 0.3 2.9 2 1 0 2 2 2 0 Purple acid Phosphatase, N-terminal domain GPI-anchored PF10342.9 KXH47544.1 - 1.2 9.9 5.9 0.71 10.7 0.2 3.1 3 0 0 3 3 3 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family p450 PF00067.22 KXH47545.1 - 1.5e-64 218.5 0.0 3.1e-64 217.5 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 WG_beta_rep PF14903.6 KXH47545.1 - 0.043 14.1 0.2 0.098 13.0 0.2 1.6 1 0 0 1 1 1 0 WG containing repeat ABC2_membrane PF01061.24 KXH47547.1 - 4.7e-82 274.5 60.0 1.6e-44 151.9 21.9 3.4 4 0 0 4 4 4 2 ABC-2 type transporter PDR_CDR PF06422.12 KXH47547.1 - 6.6e-42 141.3 1.3 3e-34 116.8 0.0 3.4 2 0 0 2 2 2 2 CDR ABC transporter ABC_tran PF00005.27 KXH47547.1 - 8.3e-38 130.0 0.0 2.8e-17 63.5 0.0 3.3 4 0 0 4 4 3 2 ABC transporter ABC_trans_N PF14510.6 KXH47547.1 - 3.3e-17 62.9 0.0 7.9e-17 61.6 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 KXH47547.1 - 1.6e-07 31.9 0.1 0.0069 16.8 0.0 2.9 3 0 0 3 3 3 2 AAA ATPase domain AAA_25 PF13481.6 KXH47547.1 - 3.6e-06 26.7 0.2 5e-05 23.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KXH47547.1 - 4e-06 27.4 0.0 0.00038 21.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KXH47547.1 - 9.9e-06 25.8 0.1 0.013 15.6 0.0 2.8 3 0 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 KXH47547.1 - 1.1e-05 25.4 0.1 0.0029 17.5 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 KXH47547.1 - 0.0001 22.0 0.8 0.03 14.0 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain SMC_N PF02463.19 KXH47547.1 - 0.00068 19.1 0.0 0.22 11.0 0.0 3.6 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_17 PF13207.6 KXH47547.1 - 0.0016 18.9 0.4 0.35 11.3 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_21 PF13304.6 KXH47547.1 - 0.0044 16.9 0.1 1.8 8.3 0.0 2.7 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KXH47547.1 - 0.0074 16.6 0.3 3 8.1 0.1 2.9 2 0 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.7 KXH47547.1 - 0.0081 15.3 49.0 0.027 13.6 18.2 2.9 2 1 1 3 3 3 2 ABC-2 family transporter protein NACHT PF05729.12 KXH47547.1 - 0.024 14.6 0.7 2.6 8.0 0.2 2.7 2 0 0 2 2 2 0 NACHT domain cobW PF02492.19 KXH47547.1 - 0.027 14.0 0.9 0.72 9.4 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 KXH47547.1 - 0.03 14.0 1.1 2.4 7.8 0.3 2.4 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KXH47547.1 - 0.043 14.3 0.0 16 5.9 0.0 2.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 KXH47547.1 - 0.26 11.5 0.8 10 6.3 0.2 2.7 2 0 0 2 2 2 0 AAA domain TPR_12 PF13424.6 KXH47548.1 - 3.6e-13 49.6 24.6 9.7e-07 29.0 0.1 7.1 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_10 PF13374.6 KXH47548.1 - 2e-10 40.2 14.8 0.0027 17.5 0.9 7.4 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_2 PF07719.17 KXH47548.1 - 5.7e-05 22.9 30.6 2.5 8.4 1.1 8.3 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_14 PF13428.6 KXH47548.1 - 0.00024 21.7 21.2 6.3 7.9 0.1 8.5 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_8 PF13181.6 KXH47548.1 - 0.019 15.1 10.5 4.8 7.6 0.2 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 KXH47548.1 - 0.028 15.1 12.5 1.3 9.8 0.1 6.2 6 2 0 6 6 6 0 Tetratricopeptide repeat TPR_1 PF00515.28 KXH47548.1 - 0.063 13.1 21.0 3 7.8 0.3 7.3 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_5 PF12688.7 KXH47548.1 - 0.17 12.1 4.0 0.32 11.3 0.1 3.4 4 1 1 5 5 5 0 Tetratrico peptide repeat TPR_6 PF13174.6 KXH47548.1 - 0.23 12.2 12.8 1.9 9.3 1.5 6.0 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_7 PF13176.6 KXH47548.1 - 8.1 6.7 21.1 14 6.0 0.5 7.7 8 0 0 8 8 8 0 Tetratricopeptide repeat NmrA PF05368.13 KXH47549.1 - 1.9e-14 53.8 0.0 2.5e-14 53.4 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family Sacchrp_dh_NADP PF03435.18 KXH47549.1 - 0.011 15.9 0.0 0.033 14.5 0.0 1.8 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 KXH47549.1 - 0.12 12.5 0.0 5.5 7.1 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Pectate_lyase PF03211.13 KXH47551.1 - 2.9e-87 291.5 5.5 3.9e-87 291.0 5.5 1.1 1 0 0 1 1 1 1 Pectate lyase SepZ PF06066.11 KXH47552.1 - 0.00032 20.9 0.8 0.00065 19.9 0.1 1.8 2 0 0 2 2 2 1 SepZ Ribonuc_L-PSP PF01042.21 KXH47555.1 - 2.2e-16 60.0 0.0 2.9e-16 59.6 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP MFS_1 PF07690.16 KXH47556.1 - 2.6e-29 102.2 25.3 3.9e-29 101.7 25.3 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF3487 PF11990.8 KXH47556.1 - 0.88 9.5 5.1 0.65 9.9 0.3 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3487) Glyco_hydro_16 PF00722.21 KXH47559.1 - 1.2e-12 47.7 0.1 1.7e-12 47.2 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.15 KXH47559.1 - 3.2e-06 25.8 0.5 0.0079 14.6 0.0 2.1 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) DUF2201 PF09967.9 KXH47560.1 - 0.12 12.5 0.1 0.77 9.9 0.0 2.1 1 1 1 2 2 2 0 VWA-like domain (DUF2201) p450 PF00067.22 KXH47561.1 - 2.8e-22 79.1 0.1 9.6e-22 77.3 0.1 1.8 1 1 0 1 1 1 1 Cytochrome P450 BAALC_N PF06989.12 KXH47561.1 - 0.16 12.3 0.3 0.72 10.2 0.0 2.0 2 0 0 2 2 2 0 BAALC N-terminus CM2 PF03021.14 KXH47566.1 - 0.063 13.1 1.1 0.14 11.9 1.1 1.5 1 0 0 1 1 1 0 Influenza C virus M2 protein Ninjurin PF04923.12 KXH47566.1 - 0.28 11.1 9.0 0.1 12.6 2.5 2.4 2 0 0 2 2 2 0 Ninjurin Sulfotransfer_4 PF17784.1 KXH47567.1 - 4.6e-70 235.8 0.0 5.4e-70 235.6 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KXH47567.1 - 0.014 15.8 0.2 0.28 11.5 0.0 2.5 1 1 1 2 2 2 0 Sulfotransferase family MAP65_ASE1 PF03999.12 KXH47568.1 - 3.7 6.1 10.1 5 5.7 10.1 1.3 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Pneumo_att_G PF05539.11 KXH47568.1 - 5.7 6.4 19.4 7.7 6.0 19.4 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Aminotran_1_2 PF00155.21 KXH47570.1 - 4.5e-69 233.4 0.0 5.3e-69 233.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 KXH47570.1 - 0.00051 19.4 0.0 0.0009 18.6 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 KXH47570.1 - 0.0019 17.6 0.1 0.0063 15.9 0.1 1.8 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 KXH47570.1 - 0.0025 16.4 0.1 0.0054 15.3 0.1 1.5 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 KXH47570.1 - 0.0068 15.4 0.0 0.018 14.0 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class-V Foie-gras_1 PF11817.8 KXH47570.1 - 0.053 13.1 0.2 0.16 11.6 0.0 1.7 2 0 0 2 2 2 0 Foie gras liver health family 1 Glyco_trans_2_3 PF13632.6 KXH47572.1 - 0.078 12.9 0.8 0.15 11.9 0.0 1.8 2 0 0 2 2 2 0 Glycosyl transferase family group 2 FAP PF07174.11 KXH47572.1 - 0.34 10.3 14.5 1.3 8.5 3.5 2.1 2 0 0 2 2 2 0 Fibronectin-attachment protein (FAP) DAO PF01266.24 KXH47573.1 - 8e-50 170.4 0.0 1.2e-49 169.8 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 KXH47573.1 - 5.7e-39 132.9 0.0 2e-38 131.1 0.0 1.9 2 0 0 2 2 2 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_binding_2 PF00890.24 KXH47573.1 - 8.4e-08 31.7 2.1 0.0054 15.9 1.2 2.3 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.7 KXH47573.1 - 3e-06 26.8 0.4 0.00039 19.9 0.3 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXH47573.1 - 0.00095 18.5 0.1 0.002 17.4 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXH47573.1 - 0.0055 16.9 0.2 0.27 11.5 0.2 3.2 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KXH47573.1 - 0.019 14.2 0.0 0.055 12.7 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 KXH47573.1 - 0.028 14.3 0.1 0.054 13.4 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.22 KXH47573.1 - 0.036 13.2 0.3 0.2 10.7 0.1 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A HI0933_like PF03486.14 KXH47573.1 - 0.078 11.7 0.2 0.12 11.0 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein He_PIG PF05345.12 KXH47573.1 - 0.12 12.6 0.3 0.29 11.3 0.3 1.7 1 0 0 1 1 1 0 Putative Ig domain Pyr_redox PF00070.27 KXH47573.1 - 0.15 12.6 0.2 0.49 11.0 0.2 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXH47573.1 - 0.34 10.1 1.1 1.5 8.0 0.1 2.4 3 0 0 3 3 3 0 Thi4 family MIP PF00230.20 KXH47574.1 - 5.8e-52 176.7 9.1 7.2e-52 176.4 9.1 1.1 1 0 0 1 1 1 1 Major intrinsic protein G3P_acyltransf PF02660.15 KXH47574.1 - 3 7.9 11.7 6 6.9 11.7 1.5 1 1 0 1 1 1 0 Glycerol-3-phosphate acyltransferase FGGY_C PF02782.16 KXH47575.1 - 7e-72 241.3 1.1 1.2e-71 240.6 1.1 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 KXH47575.1 - 5e-66 222.7 0.0 6.5e-66 222.4 0.0 1.1 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.20 KXH47575.1 - 0.043 13.3 0.3 1 8.8 0.0 2.2 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family HTH_IclR PF09339.10 KXH47575.1 - 0.11 12.3 0.1 0.68 9.8 0.0 2.3 2 0 0 2 2 2 0 IclR helix-turn-helix domain Fungal_trans PF04082.18 KXH47577.1 - 2.2e-18 66.3 0.2 3.8e-18 65.5 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH47577.1 - 3.4e-08 33.5 11.2 6.6e-08 32.5 10.2 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gelsolin PF00626.22 KXH47578.1 - 1.6e-34 117.6 0.3 5.5e-12 45.4 0.0 3.3 3 0 0 3 3 3 3 Gelsolin repeat HATPase_c PF02518.26 KXH47580.1 - 6e-31 107.3 0.1 1.4e-30 106.1 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KXH47580.1 - 1.6e-21 76.6 0.2 4.1e-21 75.2 0.2 1.8 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 KXH47580.1 - 4.2e-19 68.3 0.2 1.4e-18 66.6 0.2 2.1 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF_2 PF13185.6 KXH47580.1 - 2e-13 50.8 0.2 7.3e-13 49.0 0.0 2.1 2 0 0 2 2 1 1 GAF domain AAA_16 PF13191.6 KXH47580.1 - 9.6e-13 48.9 0.5 4.3e-12 46.7 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain Pkinase PF00069.25 KXH47580.1 - 2.3e-09 37.0 0.0 4.5e-08 32.8 0.0 2.3 2 0 0 2 2 2 1 Protein kinase domain GAF PF01590.26 KXH47580.1 - 1.5e-07 32.1 0.0 4.8e-07 30.5 0.0 2.0 1 0 0 1 1 1 1 GAF domain HATPase_c_3 PF13589.6 KXH47580.1 - 0.00016 21.5 0.0 0.00035 20.4 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GAF_3 PF13492.6 KXH47580.1 - 0.0013 19.1 0.0 0.0042 17.4 0.0 2.0 1 0 0 1 1 1 1 GAF domain TPR_12 PF13424.6 KXH47580.1 - 0.011 16.1 12.2 0.046 14.0 0.1 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat Pkinase_Tyr PF07714.17 KXH47580.1 - 0.082 12.2 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein tyrosine kinase TPR_14 PF13428.6 KXH47580.1 - 2.5 9.2 7.4 19 6.4 0.1 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 KXH47580.1 - 9.8 6.6 9.1 0.8 10.0 0.2 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Pkinase PF00069.25 KXH47586.1 - 1.3e-73 247.7 0.0 2e-73 247.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXH47586.1 - 2.6e-37 128.5 0.0 6.8e-37 127.1 0.0 1.7 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KXH47586.1 - 0.00062 19.2 0.3 1 8.6 0.0 2.6 3 0 0 3 3 3 2 Kinase-like APH PF01636.23 KXH47586.1 - 0.016 15.2 0.0 0.11 12.4 0.0 2.3 2 1 1 3 3 3 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXH47586.1 - 0.022 13.6 0.8 0.074 11.8 0.0 2.1 2 0 0 2 2 2 0 Fungal protein kinase SGL PF08450.12 KXH47588.1 - 3.2e-10 40.0 0.2 5.4e-07 29.4 0.0 2.8 2 2 1 3 3 3 2 SMP-30/Gluconolactonase/LRE-like region Na_H_Exchanger PF00999.21 KXH47589.1 - 7.6e-34 117.1 10.1 9.8e-34 116.8 10.1 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.6 KXH47589.1 - 0.013 15.5 4.5 0.015 15.4 0.3 3.1 4 0 0 4 4 4 0 YrhC-like protein Glyco_hydro_28 PF00295.17 KXH47590.1 - 1.7e-37 129.2 2.5 2.4e-37 128.7 2.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 PAP2_3 PF14378.6 KXH47591.1 - 1.5e-36 125.9 9.7 1.5e-36 125.9 9.7 1.4 2 0 0 2 2 2 1 PAP2 superfamily PAP2 PF01569.21 KXH47591.1 - 0.0011 18.8 2.9 0.0011 18.8 2.9 1.9 2 0 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.6 KXH47591.1 - 0.0043 17.6 0.1 0.0043 17.6 0.1 2.7 3 1 0 3 3 3 1 PAP2 superfamily C-terminal But2 PF09792.9 KXH47592.1 - 1.4e-34 119.5 1.1 4.5e-34 117.9 0.4 1.9 2 0 0 2 2 2 1 Ubiquitin 3 binding protein But2 C-terminal domain Sugar_tr PF00083.24 KXH47593.1 - 2.2e-77 260.9 13.8 3e-77 260.4 13.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH47593.1 - 6e-22 78.0 20.8 6e-22 78.0 20.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily FAD_binding_3 PF01494.19 KXH47593.1 - 2.9e-16 59.7 1.1 4.6e-15 55.7 1.1 2.2 1 1 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 KXH47593.1 - 2.6e-07 30.1 0.1 4e-07 29.5 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KXH47593.1 - 4.4e-06 26.1 0.1 0.00024 20.4 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXH47593.1 - 3.2e-05 23.7 0.2 0.00023 20.9 0.1 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXH47593.1 - 0.0001 22.4 0.0 0.00027 21.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KXH47593.1 - 0.00018 20.4 0.4 0.0019 17.0 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.6 KXH47593.1 - 0.001 18.4 0.2 0.0017 17.7 0.2 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KXH47593.1 - 0.001 18.2 0.2 0.0098 15.0 0.0 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 KXH47593.1 - 0.0029 17.0 0.1 0.0044 16.4 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase MFS_1_like PF12832.7 KXH47593.1 - 0.022 13.6 0.2 0.022 13.6 0.2 2.8 1 1 0 2 2 2 0 MFS_1 like family Pyr_redox PF00070.27 KXH47593.1 - 0.023 15.2 0.2 0.077 13.6 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXH47593.1 - 0.04 13.1 0.1 0.089 12.0 0.1 1.5 1 0 0 1 1 1 0 Thi4 family AlaDh_PNT_C PF01262.21 KXH47593.1 - 0.068 12.4 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 KXH47593.1 - 0.091 12.6 0.1 0.15 11.9 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Rab5ip PF07019.12 KXH47593.1 - 0.75 10.4 5.4 2.7 8.6 5.4 2.0 1 0 0 1 1 1 0 Rab5-interacting protein (Rab5ip) Cys_Met_Meta_PP PF01053.20 KXH47594.1 - 1.8e-125 418.5 0.0 2e-125 418.3 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 KXH47594.1 - 2.4e-07 30.4 3.1 5.1e-07 29.3 3.1 1.4 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 KXH47594.1 - 6.5e-05 22.3 0.1 0.00011 21.5 0.1 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Met_gamma_lyase PF06838.11 KXH47594.1 - 0.0017 16.9 0.1 0.0026 16.4 0.1 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase Aminotran_5 PF00266.19 KXH47594.1 - 0.007 15.4 0.4 0.06 12.3 0.2 2.0 1 1 1 2 2 2 1 Aminotransferase class-V SepSecS PF05889.13 KXH47594.1 - 0.015 14.0 0.1 0.025 13.3 0.1 1.3 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Radical_SAM PF04055.21 KXH47594.1 - 0.034 14.5 0.0 1.3 9.3 0.0 2.4 2 0 0 2 2 2 0 Radical SAM superfamily Asparaginase_C PF17763.1 KXH47594.1 - 0.039 14.2 2.5 0.082 13.1 0.1 2.4 3 0 0 3 3 3 0 Glutaminase/Asparaginase C-terminal domain Beta_elim_lyase PF01212.21 KXH47594.1 - 0.057 12.7 0.6 0.13 11.5 0.7 1.4 1 1 0 1 1 1 0 Beta-eliminating lyase TNV_CP PF03898.13 KXH47594.1 - 0.068 12.4 0.1 0.13 11.6 0.1 1.4 1 0 0 1 1 1 0 Satellite tobacco necrosis virus coat protein FAD_binding_3 PF01494.19 KXH47595.1 - 4.6e-14 52.4 2.5 3.4e-11 43.0 0.0 3.1 3 0 0 3 3 3 2 FAD binding domain SE PF08491.10 KXH47595.1 - 2.1e-06 27.0 0.0 2e-05 23.8 0.0 2.3 1 1 0 1 1 1 1 Squalene epoxidase NAD_binding_8 PF13450.6 KXH47595.1 - 2.6e-05 24.4 0.2 7e-05 23.0 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXH47595.1 - 5.9e-05 22.8 1.8 0.00011 21.9 0.8 2.0 1 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXH47595.1 - 0.043 13.1 0.2 0.083 12.1 0.1 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXH47595.1 - 0.12 11.4 0.6 0.19 10.7 0.6 1.3 1 0 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.14 KXH47595.1 - 0.13 11.1 0.6 1.4 7.6 0.3 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Pyr_redox PF00070.27 KXH47595.1 - 0.19 12.3 0.2 0.53 10.9 0.2 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase p450 PF00067.22 KXH47596.1 - 6.4e-36 124.1 0.0 7.5e-36 123.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 adh_short_C2 PF13561.6 KXH47597.1 - 6.4e-46 156.8 0.0 1e-45 156.1 0.0 1.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXH47597.1 - 3.8e-37 127.6 0.0 5.1e-37 127.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXH47597.1 - 1.1e-06 28.7 0.0 1.9e-05 24.7 0.0 2.1 1 1 0 1 1 1 1 KR domain Glyoxalase PF00903.25 KXH47598.1 - 3.3e-10 40.2 4.4 4.5e-06 26.9 2.9 2.3 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily FAA_hydrolase PF01557.18 KXH47599.1 - 6.5e-61 205.8 0.0 7.8e-61 205.5 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Amidohydro_1 PF01979.20 KXH47600.1 - 2.2e-19 70.0 0.7 1.8e-10 40.7 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 KXH47600.1 - 1.8e-15 57.4 0.3 9.6e-10 38.5 0.1 2.2 2 0 0 2 2 2 2 Amidohydrolase family NmrA PF05368.13 KXH47601.1 - 1.1e-27 97.2 0.1 1.5e-27 96.7 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXH47601.1 - 1.2e-23 84.0 0.1 2.6e-23 82.9 0.0 1.7 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KXH47601.1 - 9.6e-06 25.2 0.4 3.3e-05 23.5 0.1 2.1 1 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 KXH47601.1 - 0.004 17.6 0.2 0.028 14.9 0.1 2.2 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 KXH47601.1 - 0.0094 16.4 1.0 0.19 12.2 0.1 2.4 2 1 0 2 2 2 1 Putative NAD(P)-binding 3Beta_HSD PF01073.19 KXH47601.1 - 0.012 14.6 0.7 0.08 11.9 0.0 2.0 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Shikimate_DH PF01488.20 KXH47601.1 - 0.016 15.2 0.2 0.047 13.8 0.0 1.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_4 PF07993.12 KXH47601.1 - 0.041 13.1 0.0 0.078 12.1 0.0 1.5 1 0 0 1 1 1 0 Male sterility protein adh_short PF00106.25 KXH47601.1 - 0.088 12.2 0.7 0.18 11.3 0.1 1.8 2 0 0 2 2 2 0 short chain dehydrogenase EVC2_like PF12297.8 KXH47601.1 - 0.09 11.4 0.0 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein Fungal_trans PF04082.18 KXH47602.1 - 5.5e-13 48.6 0.0 1e-12 47.7 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH47602.1 - 1.1e-08 35.0 10.5 2.3e-08 34.0 10.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Beta-lactamase PF00144.24 KXH47603.1 - 2.1e-26 93.0 0.0 2.7e-26 92.6 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Fungal_trans PF04082.18 KXH47604.1 - 1.6e-08 33.9 0.1 3.6e-08 32.8 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Flavin_Reduct PF01613.18 KXH47605.1 - 8.4e-13 48.6 0.0 1.2e-12 48.1 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain Cupin_2 PF07883.11 KXH47606.1 - 1.5e-13 50.2 0.2 3.2e-13 49.2 0.2 1.6 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 KXH47606.1 - 0.0097 15.5 0.0 0.014 15.0 0.0 1.2 1 0 0 1 1 1 1 Cupin p450 PF00067.22 KXH47607.1 - 1.1e-69 235.4 0.0 1.5e-69 235.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 CorA PF01544.18 KXH47608.1 - 0.00026 20.4 3.6 0.00054 19.4 3.6 1.7 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Pkinase PF00069.25 KXH47609.1 - 3e-17 62.9 0.0 6.4e-17 61.8 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXH47609.1 - 1.4e-06 27.8 0.0 1.6e-05 24.4 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase HsbA PF12296.8 KXH47621.1 - 1.9e-15 57.4 3.4 2.6e-15 56.9 3.4 1.2 1 0 0 1 1 1 1 Hydrophobic surface binding protein A mTERF PF02536.14 KXH47621.1 - 0.022 13.7 0.2 0.026 13.4 0.2 1.0 1 0 0 1 1 1 0 mTERF KIP1 PF07765.12 KXH47621.1 - 0.046 13.9 0.1 0.19 11.9 0.0 1.9 2 0 0 2 2 2 0 KIP1-like protein OPT PF03169.15 KXH47623.1 - 3.7e-165 551.1 54.0 4.3e-165 550.9 54.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF5592 PF17332.2 KXH47623.1 - 0.52 10.9 4.6 0.48 11.0 1.6 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5592) DUF2427 PF10348.9 KXH47623.1 - 0.96 9.3 8.9 0.08 12.7 1.2 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF2427) MFS_1 PF07690.16 KXH47624.1 - 8.8e-06 24.9 0.9 1.1e-05 24.5 0.1 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily HNH_2 PF13391.6 KXH47625.1 - 2.3e-10 40.4 0.5 5.3e-10 39.3 0.5 1.7 1 0 0 1 1 1 1 HNH endonuclease Hamartin PF04388.12 KXH47625.1 - 0.021 13.5 2.9 0.033 12.9 2.9 1.3 1 0 0 1 1 1 0 Hamartin protein MSA-2c PF12238.8 KXH47625.1 - 0.027 14.5 4.4 0.042 13.8 4.4 1.3 1 0 0 1 1 1 0 Merozoite surface antigen 2c ORC6 PF05460.13 KXH47625.1 - 0.048 12.9 6.1 0.1 11.9 6.1 1.5 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Suf PF05843.14 KXH47625.1 - 0.083 12.9 1.0 0.18 11.8 1.0 1.5 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Spc7_N PF15402.6 KXH47625.1 - 0.19 10.0 14.9 0.34 9.1 14.9 1.3 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 Ndc1_Nup PF09531.10 KXH47625.1 - 4.8 5.8 4.4 7.1 5.2 4.4 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CENP-U PF13097.6 KXH47625.1 - 5.9 6.8 9.1 13 5.7 9.1 1.5 1 0 0 1 1 1 0 CENP-A nucleosome associated complex (NAC) subunit Dioxygenase_C PF00775.21 KXH47626.1 - 3.6e-48 163.4 0.0 4.7e-48 163.0 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 KXH47626.1 - 7.1e-30 102.7 0.1 1.1e-29 102.1 0.1 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 KXH47626.1 - 0.00015 21.9 0.0 0.0013 19.0 0.0 2.3 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain DUF4198 PF10670.9 KXH47626.1 - 0.12 12.7 0.0 0.21 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4198) CoA_transf_3 PF02515.17 KXH47627.1 - 4.5e-43 147.8 0.0 4.4e-40 137.9 0.0 2.2 2 0 0 2 2 2 2 CoA-transferase family III ISET-FN3_linker PF16625.5 KXH47627.1 - 0.084 13.4 0.2 0.34 11.5 0.5 1.9 2 0 0 2 2 2 0 Unstructured linking region I-set and fnIII on Brother of CDO Fungal_trans PF04082.18 KXH47628.1 - 3.4e-08 32.9 0.1 5.8e-08 32.1 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH47628.1 - 1.1e-06 28.7 10.5 1.1e-06 28.7 10.5 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_6 PF12697.7 KXH47629.1 - 6.4e-18 66.2 0.0 7.5e-18 65.9 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXH47629.1 - 0.00011 21.6 0.0 0.00023 20.5 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 KXH47629.1 - 0.013 15.6 0.0 0.038 14.1 0.0 1.7 2 0 0 2 2 2 0 Thioesterase domain Abhydrolase_8 PF06259.12 KXH47629.1 - 0.15 11.7 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase FAD_binding_3 PF01494.19 KXH47630.1 - 2.9e-15 56.4 2.0 1.1e-13 51.1 2.0 2.6 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KXH47630.1 - 2.2e-06 27.5 0.2 0.00017 21.3 0.1 2.5 1 1 1 3 3 3 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KXH47630.1 - 6.9e-05 22.9 0.3 0.0005 20.1 0.3 2.2 1 1 0 1 1 1 1 FAD-NAD(P)-binding SE PF08491.10 KXH47630.1 - 8.4e-05 21.7 0.0 0.0032 16.5 0.0 2.1 2 0 0 2 2 2 1 Squalene epoxidase Pyr_redox_2 PF07992.14 KXH47630.1 - 0.00019 20.7 0.1 0.0064 15.8 0.0 2.1 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXH47630.1 - 0.0013 18.9 0.1 0.0036 17.5 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KXH47630.1 - 0.014 14.5 0.1 0.026 13.6 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.22 KXH47630.1 - 0.048 12.7 0.0 0.08 12.0 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A HI0933_like PF03486.14 KXH47630.1 - 0.11 11.2 0.0 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Deltaretro_Tax PF05599.11 KXH47630.1 - 1 9.9 4.7 1 9.9 1.0 2.6 3 0 0 3 3 3 0 Deltaretrovirus Tax protein AA_permease_2 PF13520.6 KXH47631.1 - 1.9e-37 129.1 54.8 2.4e-37 128.8 54.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXH47631.1 - 6.5e-17 61.3 43.4 9.1e-17 60.8 43.4 1.2 1 0 0 1 1 1 1 Amino acid permease VIT1 PF01988.19 KXH47631.1 - 0.009 15.9 0.2 0.009 15.9 0.2 3.0 2 1 0 2 2 2 1 VIT family p450 PF00067.22 KXH47632.1 - 1.4e-30 106.5 0.0 2.3e-30 105.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 DIT1_PvcA PF05141.12 KXH47633.1 - 2.6e-96 322.3 0.0 3.9e-96 321.8 0.0 1.3 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein TauD PF02668.16 KXH47633.1 - 1.5e-25 90.5 0.0 4.3e-25 89.0 0.0 1.8 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family FAD_binding_3 PF01494.19 KXH47634.1 - 4.2e-62 210.4 0.0 6.3e-62 209.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KXH47634.1 - 5.6e-05 22.5 0.1 0.0053 16.0 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXH47634.1 - 0.0002 20.8 1.8 0.015 14.6 0.4 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXH47634.1 - 0.00074 19.7 0.0 0.0019 18.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KXH47634.1 - 0.0018 17.0 0.3 0.0031 16.3 0.0 1.4 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 KXH47634.1 - 0.0021 17.4 0.0 0.0037 16.5 0.0 1.3 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 KXH47634.1 - 0.0022 17.6 4.5 0.018 14.6 0.1 3.3 2 1 0 4 4 4 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KXH47634.1 - 0.0024 17.0 0.2 0.26 10.3 0.1 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox PF00070.27 KXH47634.1 - 0.01 16.3 0.4 0.16 12.6 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.16 KXH47635.1 - 3e-24 85.6 64.4 9.2e-21 74.1 38.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily UPRTase PF14681.6 KXH47643.1 - 6.2e-35 120.5 0.0 1.1e-34 119.8 0.0 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase HAD PF12710.7 KXH47643.1 - 2.7e-19 70.3 0.1 7.8e-19 68.8 0.1 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase AAA_17 PF13207.6 KXH47643.1 - 1.7e-11 44.7 0.0 3.4e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain Hydrolase PF00702.26 KXH47643.1 - 2e-07 31.5 0.0 7.4e-07 29.7 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Pribosyltran PF00156.27 KXH47643.1 - 0.00041 19.9 0.7 0.0041 16.7 0.7 2.2 1 1 0 1 1 1 1 Phosphoribosyl transferase domain Zeta_toxin PF06414.12 KXH47643.1 - 0.15 11.3 0.0 0.35 10.1 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin Hydrolase_3 PF08282.12 KXH47643.1 - 0.23 11.2 0.0 0.42 10.3 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase MFS_1 PF07690.16 KXH47644.1 - 3.1e-46 157.9 44.7 1.1e-45 156.1 44.7 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KXH47644.1 - 1.6e-09 36.8 22.6 2.1e-09 36.4 22.6 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Auxin_canalis PF05703.11 KXH47644.1 - 0.14 12.1 4.7 0.27 11.2 4.7 1.3 1 0 0 1 1 1 0 Auxin canalisation DUF5305 PF17231.2 KXH47644.1 - 1.3 8.4 3.9 2.5 7.5 0.0 2.9 3 0 0 3 3 3 0 Family of unknown function (DUF5305) TMEM100 PF16311.5 KXH47644.1 - 9.4 5.8 6.3 9.1 5.9 0.0 3.3 3 0 0 3 3 3 0 Transmembrane protein 100 Fungal_trans PF04082.18 KXH47645.1 - 2.1e-20 72.9 0.0 3.5e-20 72.2 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH47645.1 - 4.1e-09 36.4 9.2 6.7e-09 35.7 9.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aconitase PF00330.20 KXH47646.1 - 1.8e-105 353.6 1.5 1.5e-104 350.6 1.5 2.1 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KXH47646.1 - 6e-24 84.8 0.0 1.2e-23 83.9 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain IPPT PF01715.17 KXH47647.1 - 1.4e-62 211.5 0.5 2.1e-62 210.9 0.0 1.4 2 0 0 2 2 2 1 IPP transferase zf-met PF12874.7 KXH47647.1 - 0.00042 20.6 1.7 0.00076 19.8 1.7 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KXH47647.1 - 0.00064 19.9 1.7 0.0012 19.1 1.7 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding Rpr2 PF04032.16 KXH47647.1 - 0.035 14.4 0.9 0.075 13.3 0.9 1.4 1 0 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-C2H2_2 PF12756.7 KXH47647.1 - 0.045 14.1 1.1 0.09 13.1 1.1 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) SecY PF00344.20 KXH47648.1 - 2.7e-71 240.3 7.7 3.5e-71 240.0 7.7 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 KXH47648.1 - 3.2e-17 62.0 0.2 1e-16 60.5 0.2 2.0 1 0 0 1 1 1 1 Plug domain of Sec61p RELT PF12606.8 KXH47648.1 - 1.4 8.0 3.6 4.1 6.5 3.6 1.8 1 0 0 1 1 1 0 Tumour necrosis factor receptor superfamily member 19 ABC_membrane PF00664.23 KXH47649.1 - 7.5e-57 193.1 21.7 1.6e-33 116.5 7.5 3.3 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.27 KXH47649.1 - 3.9e-49 166.7 4.7 2.8e-30 105.6 0.0 3.4 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.19 KXH47649.1 - 5.8e-05 22.6 13.9 0.0068 15.9 0.2 4.5 4 1 0 4 4 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KXH47649.1 - 0.00019 21.1 0.5 0.58 9.9 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain T2SSE PF00437.20 KXH47649.1 - 0.00022 20.4 0.1 0.019 14.1 0.3 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein MMR_HSR1 PF01926.23 KXH47649.1 - 0.00054 20.0 0.0 0.12 12.5 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_21 PF13304.6 KXH47649.1 - 0.00068 19.5 1.0 8.9 6.0 0.0 3.6 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KXH47649.1 - 0.0011 18.9 0.0 0.87 9.5 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase IstB_IS21 PF01695.17 KXH47649.1 - 0.0017 18.1 1.1 0.2 11.4 0.0 3.3 4 0 0 4 4 4 1 IstB-like ATP binding protein AAA_22 PF13401.6 KXH47649.1 - 0.002 18.4 0.1 11 6.3 0.0 3.6 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.6 KXH47649.1 - 0.0027 18.1 3.8 0.71 10.2 0.0 3.2 3 0 0 3 3 2 2 AAA ATPase domain AAA_23 PF13476.6 KXH47649.1 - 0.0032 18.0 0.0 0.0032 18.0 0.0 4.2 4 1 0 4 4 2 2 AAA domain AAA_25 PF13481.6 KXH47649.1 - 0.018 14.6 0.1 1 8.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KXH47649.1 - 0.019 15.4 0.4 10 6.6 0.0 3.4 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) CbiA PF01656.23 KXH47649.1 - 0.024 14.7 0.5 0.8 9.8 0.0 3.1 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF87 PF01935.17 KXH47649.1 - 0.027 14.6 0.0 0.027 14.6 0.0 3.7 3 0 0 3 3 2 0 Helicase HerA, central domain DEAD PF00270.29 KXH47649.1 - 0.077 12.8 0.1 10 5.9 0.0 3.3 3 0 0 3 3 3 0 DEAD/DEAH box helicase AAA_7 PF12775.7 KXH47649.1 - 0.12 11.9 0.1 18 4.8 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region Adeno_IVa2 PF02456.15 KXH47649.1 - 0.14 11.0 0.0 0.47 9.2 0.0 1.8 2 0 0 2 2 2 0 Adenovirus IVa2 protein DUF4192 PF13830.6 KXH47649.1 - 2.6 8.0 6.6 5.1 7.1 6.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) TIP120 PF08623.10 KXH47650.1 - 1.7e-71 239.4 0.4 3.6e-69 231.8 0.0 3.6 3 0 0 3 3 3 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.6 KXH47650.1 - 1.3e-11 44.7 13.1 0.19 12.2 0.9 8.4 8 1 1 9 9 9 4 HEAT repeats HEAT PF02985.22 KXH47650.1 - 3.6e-08 33.0 20.2 0.19 12.1 0.1 11.2 13 0 0 13 13 12 3 HEAT repeat Adaptin_N PF01602.20 KXH47650.1 - 2.1e-06 26.6 12.6 0.2 10.2 0.2 6.1 4 1 2 6 6 6 3 Adaptin N terminal region HEAT_EZ PF13513.6 KXH47650.1 - 3.1e-06 27.6 9.7 6.2 7.4 0.0 10.5 12 1 0 12 12 12 1 HEAT-like repeat RTP1_C1 PF10363.9 KXH47650.1 - 3.4e-05 24.0 5.2 0.37 11.0 0.0 5.6 5 1 1 6 6 6 2 Required for nuclear transport of RNA pol II C-terminus 1 Cnd1 PF12717.7 KXH47650.1 - 9.2e-05 22.5 12.6 0.75 9.8 0.0 6.0 5 1 1 6 6 6 3 non-SMC mitotic condensation complex subunit 1 RIX1 PF08167.12 KXH47650.1 - 0.0064 16.3 2.6 0.19 11.4 0.0 3.9 4 0 0 4 4 4 1 rRNA processing/ribosome biogenesis DUF4042 PF13251.6 KXH47650.1 - 0.02 14.6 8.7 0.22 11.2 0.3 5.4 5 1 0 5 5 5 0 Domain of unknown function (DUF4042) RICTOR_N PF14664.6 KXH47650.1 - 0.028 13.4 6.1 0.63 9.0 0.0 3.8 4 0 0 4 4 4 0 Rapamycin-insensitive companion of mTOR, N-term Cnd3 PF12719.7 KXH47650.1 - 0.11 11.7 0.4 24 4.0 0.0 4.1 5 0 0 5 5 5 0 Nuclear condensing complex subunits, C-term domain DUF3361 PF11841.8 KXH47650.1 - 0.11 12.4 9.9 3.7 7.5 0.0 5.0 5 2 1 7 7 6 0 Domain of unknown function (DUF3361) CENP-B_dimeris PF09026.10 KXH47650.1 - 4.5 7.7 12.9 10 6.5 12.9 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Mitofilin PF09731.9 KXH47651.1 - 0.98 8.2 45.8 1.3 7.8 45.8 1.3 1 0 0 1 1 1 0 Mitochondrial inner membrane protein PhoLip_ATPase_C PF16212.5 KXH47652.1 - 7.2e-73 245.4 20.5 7.2e-73 245.4 20.5 1.9 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KXH47652.1 - 6.3e-24 83.5 0.6 3.8e-23 81.0 0.1 2.5 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KXH47652.1 - 1.8e-14 54.5 0.0 1.2e-08 35.5 0.0 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KXH47652.1 - 8.2e-14 51.5 0.0 1.3e-12 47.6 0.0 2.4 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 KXH47652.1 - 7.2e-13 48.4 0.0 2.2e-12 46.9 0.0 1.8 1 0 0 1 1 1 1 E1-E2 ATPase GGDEF_2 PF17853.1 KXH47652.1 - 0.00028 21.1 0.3 0.16 12.2 0.0 2.8 2 0 0 2 2 2 2 GGDEF-like domain Hydrolase_3 PF08282.12 KXH47652.1 - 0.0029 17.4 0.0 0.011 15.5 0.0 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Homeodomain PF00046.29 KXH47653.1 - 1.5e-19 69.6 4.3 3.4e-19 68.4 4.3 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KXH47653.1 - 0.0015 18.4 0.5 0.0047 16.8 0.5 1.9 1 0 0 1 1 1 1 Homeobox KN domain NAM-associated PF14303.6 KXH47653.1 - 0.27 12.0 5.4 0.48 11.1 5.4 1.3 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Adaptin_binding PF10199.9 KXH47655.1 - 1.9e-15 57.5 6.5 4.3e-15 56.4 6.5 1.6 1 1 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 Wbp11 PF09429.10 KXH47655.1 - 0.33 11.4 7.8 0.34 11.3 6.1 1.9 2 0 0 2 2 2 0 WW domain binding protein 11 DUF3446 PF11928.8 KXH47655.1 - 3.3 8.1 13.5 1.1 9.6 10.2 1.9 2 0 0 2 2 2 0 Early growth response N-terminal domain OATP PF03137.20 KXH47656.1 - 0.19 10.0 0.2 0.23 9.7 0.2 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family RNase_H PF00075.24 KXH47721.1 - 4e-12 46.5 0.8 4e-12 46.5 0.8 1.7 2 0 0 2 2 2 1 RNase H CENP-K PF11802.8 KXH47770.1 - 3.6e-09 36.6 6.2 0.0052 16.4 6.2 2.8 2 1 0 3 3 3 2 Centromere-associated protein K FapA PF03961.13 KXH47770.1 - 0.21 10.1 4.0 4.9 5.6 0.1 2.3 2 0 0 2 2 2 0 Flagellar Assembly Protein A Lzipper-MIP1 PF14389.6 KXH47770.1 - 0.23 11.8 7.1 6.3 7.2 0.1 2.6 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 BAR_3 PF16746.5 KXH47770.1 - 0.56 9.9 8.1 0.083 12.6 2.9 2.0 2 0 0 2 2 2 0 BAR domain of APPL family DUF745 PF05335.13 KXH47770.1 - 0.81 9.4 0.0 0.81 9.4 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF745) Rbsn PF11464.8 KXH47770.1 - 0.93 9.3 9.3 5.6 6.8 0.6 4.4 3 1 1 4 4 4 0 Rabenosyn Rab binding domain Atg14 PF10186.9 KXH47770.1 - 1.4 7.9 11.8 2.3 7.2 5.1 2.2 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Fib_alpha PF08702.10 KXH47770.1 - 2 8.6 8.6 5.1 7.3 0.2 2.5 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family MCU PF04678.13 KXH47770.1 - 6 6.9 8.0 1.9 8.6 2.1 2.3 2 0 0 2 2 2 0 Mitochondrial calcium uniporter DUF4404 PF14357.6 KXH47770.1 - 9.3 7.0 11.6 23 5.7 5.2 3.5 3 1 0 3 3 3 0 Domain of unknown function (DUF4404) KH_1 PF00013.29 KXH47771.1 - 6.8e-43 144.3 6.6 3.1e-18 65.4 0.7 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 KXH47771.1 - 1.7e-12 47.0 4.1 0.0049 16.7 0.3 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 KXH47771.1 - 1.2e-06 28.2 0.8 0.33 10.9 0.2 3.4 3 0 0 3 3 3 2 KH domain MOEP19 PF16005.5 KXH47771.1 - 3.2e-05 23.8 0.0 0.0088 16.0 0.0 2.8 3 0 0 3 3 3 1 KH-like RNA-binding domain KH_5 PF13184.6 KXH47771.1 - 0.0015 18.6 8.7 0.33 11.1 0.3 3.4 3 0 0 3 3 3 2 NusA-like KH domain ABM PF03992.16 KXH47772.1 - 0.00018 21.6 0.0 0.057 13.5 0.0 2.6 2 1 0 2 2 2 2 Antibiotic biosynthesis monooxygenase DUF3764 PF12594.8 KXH47772.1 - 0.045 13.8 0.0 0.09 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3764) DUF1330 PF07045.11 KXH47772.1 - 0.11 12.8 0.0 0.25 11.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1330) GPI-anchored PF10342.9 KXH47773.1 - 4e-23 82.0 1.7 4e-23 82.0 1.7 2.7 2 1 1 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.6 KXH47773.1 - 0.00089 19.1 0.2 0.0012 18.6 0.2 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF4448) Ribosomal_L18_c PF14204.6 KXH47775.1 - 3 8.9 0.0 3 8.9 0.0 3.1 3 0 0 3 3 3 0 Ribosomal L18 C-terminal region CIA30 PF08547.12 KXH47777.1 - 1.5e-37 129.1 0.0 1.9e-37 128.8 0.0 1.0 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) Maf_N PF08383.11 KXH47778.1 - 0.12 12.1 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Maf N-terminal region NmrA PF05368.13 KXH47781.1 - 0.035 13.6 0.0 0.043 13.4 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family MFS_1 PF07690.16 KXH47782.1 - 6.1e-19 68.2 50.9 3.2e-09 36.2 18.7 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KXH47782.1 - 1.3e-11 43.7 15.0 2e-11 43.0 15.0 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) PUCC PF03209.15 KXH47782.1 - 0.0034 16.4 8.7 0.0034 16.4 8.7 3.9 3 1 1 4 4 4 2 PUCC protein Pox_A14 PF05767.12 KXH47782.1 - 0.038 14.1 0.8 0.038 14.1 0.8 3.5 4 1 0 4 4 4 0 Poxvirus virion envelope protein A14 FAD_binding_4 PF01565.23 KXH47783.1 - 4.2e-17 62.2 1.0 7.7e-17 61.3 1.0 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KXH47783.1 - 2.7e-09 37.0 2.0 7e-09 35.7 2.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.10 KXH47783.1 - 0.0078 15.6 0.1 0.011 15.1 0.1 1.2 1 0 0 1 1 1 1 Cytokinin dehydrogenase 1, FAD and cytokinin binding Tetraspanin PF00335.20 KXH47784.1 - 0.00028 20.7 3.4 0.036 13.8 0.0 2.2 1 1 0 2 2 2 2 Tetraspanin family Peroxidase_2 PF01328.17 KXH47785.1 - 3e-41 142.0 0.0 3.9e-41 141.6 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 Alpha-amylase PF00128.24 KXH47786.1 - 5.9e-110 368.0 0.1 8.8e-110 367.4 0.1 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF3459 PF11941.8 KXH47786.1 - 0.00058 20.1 0.0 0.0021 18.3 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3459) Malt_amylase_C PF16657.5 KXH47786.1 - 0.00098 19.2 0.0 0.008 16.3 0.0 2.4 2 0 0 2 2 2 1 Maltogenic Amylase, C-terminal domain hDGE_amylase PF14701.6 KXH47786.1 - 0.0024 17.0 0.0 0.007 15.5 0.0 1.7 2 0 0 2 2 2 1 Glycogen debranching enzyme, glucanotransferase domain Glyco_hydro_42C PF08533.10 KXH47786.1 - 0.04 13.6 0.0 0.14 11.9 0.0 1.8 2 0 0 2 2 2 0 Beta-galactosidase C-terminal domain Sugar_tr PF00083.24 KXH47787.1 - 6.4e-81 272.5 14.9 6.4e-81 272.5 14.9 1.4 1 1 1 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH47787.1 - 1.2e-17 63.9 31.9 2.7e-17 62.7 28.1 2.6 1 1 2 3 3 3 2 Major Facilitator Superfamily Zn_clus PF00172.18 KXH47788.1 - 9.7e-09 35.2 9.2 1.8e-08 34.4 9.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXH47788.1 - 2.4e-06 26.8 0.8 4.2e-06 26.0 0.8 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF2263 PF10021.9 KXH47789.1 - 2.2e-21 76.8 0.0 4.5e-21 75.8 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) BCS1_N PF08740.11 KXH47790.1 - 1.9e-43 148.7 0.0 2.6e-43 148.2 0.0 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 KXH47790.1 - 2e-16 60.6 0.0 3.2e-16 60.0 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 KXH47790.1 - 0.0003 20.4 0.0 0.028 14.0 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_7 PF12775.7 KXH47790.1 - 0.00095 18.7 0.0 0.0017 17.9 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_5 PF07728.14 KXH47790.1 - 0.0013 18.7 0.0 0.0028 17.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KXH47790.1 - 0.0031 17.9 0.0 0.0069 16.8 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 KXH47790.1 - 0.0048 16.7 0.0 0.013 15.3 0.0 1.6 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KXH47790.1 - 0.015 15.5 0.0 0.029 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 KXH47790.1 - 0.021 14.0 0.0 0.041 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_33 PF13671.6 KXH47790.1 - 0.027 14.6 0.0 0.054 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KXH47790.1 - 0.033 13.9 0.0 0.073 12.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 KXH47790.1 - 0.034 14.7 0.0 0.057 13.9 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_18 PF13238.6 KXH47790.1 - 0.037 14.6 0.0 0.071 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain PPV_E1_C PF00519.17 KXH47790.1 - 0.062 12.1 0.0 0.094 11.5 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase AAA_17 PF13207.6 KXH47790.1 - 0.08 13.4 0.1 0.52 10.7 0.0 2.1 1 1 1 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KXH47790.1 - 0.086 12.9 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase RNA_helicase PF00910.22 KXH47790.1 - 0.11 12.9 0.0 0.22 12.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase ATP_bind_1 PF03029.17 KXH47790.1 - 0.13 12.0 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 KXH47790.1 - 0.13 12.2 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AFOR_C PF01314.18 KXH47790.1 - 0.13 11.2 0.0 0.2 10.6 0.0 1.1 1 0 0 1 1 1 0 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 Fringe PF02434.16 KXH47791.1 - 5.9e-09 35.7 0.5 1e-07 31.7 0.5 2.0 1 1 0 1 1 1 1 Fringe-like PAN_1 PF00024.26 KXH47791.1 - 0.00078 19.4 0.0 0.0014 18.5 0.0 1.3 1 0 0 1 1 1 1 PAN domain Galactosyl_T PF01762.21 KXH47791.1 - 0.074 12.9 0.1 0.24 11.2 0.1 1.7 1 1 1 2 2 2 0 Galactosyltransferase DUF604 PF04646.12 KXH47791.1 - 0.1 12.0 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF604 Oxysterol_BP PF01237.18 KXH47792.1 - 2.7e-64 217.3 0.4 9.4e-62 209.0 0.4 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein UCH PF00443.29 KXH47793.1 - 8.3e-39 133.6 0.5 2.1e-34 119.2 0.1 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KXH47793.1 - 2.3e-08 34.0 5.3 4.4e-07 29.8 5.4 2.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF4071 PF13281.6 KXH47793.1 - 0.071 12.1 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4071) F-box PF00646.33 KXH47794.1 - 0.016 15.1 3.2 0.11 12.4 3.2 2.4 1 1 0 1 1 1 0 F-box domain BTB PF00651.31 KXH47796.1 - 0.00019 21.6 0.0 0.00031 20.9 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain NPBW PF15180.6 KXH47798.1 - 0.18 11.7 0.1 3.2 7.6 0.0 2.4 2 0 0 2 2 2 0 Neuropeptides B and W Glyco_hydro_61 PF03443.14 KXH47799.1 - 1.3e-06 28.5 0.0 2.3e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 FAD_binding_3 PF01494.19 KXH47802.1 - 2.8e-18 66.3 0.1 9.9e-18 64.5 0.1 1.8 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KXH47802.1 - 3.3e-05 23.6 0.5 0.00038 20.2 0.2 2.0 1 1 1 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXH47802.1 - 3.3e-05 24.0 0.1 8.4e-05 22.7 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KXH47802.1 - 0.00044 19.6 0.0 0.00063 19.1 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXH47802.1 - 0.0012 18.2 0.0 0.0018 17.6 0.0 1.3 1 0 0 1 1 1 1 Thi4 family TrkA_N PF02254.18 KXH47802.1 - 0.002 18.4 0.0 0.0048 17.1 0.0 1.7 1 0 0 1 1 1 1 TrkA-N domain Pyr_redox_2 PF07992.14 KXH47802.1 - 0.0042 16.3 0.0 0.01 15.1 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXH47802.1 - 0.023 13.8 0.0 0.093 11.8 0.0 1.8 2 0 0 2 2 2 0 FAD binding domain ApbA PF02558.16 KXH47802.1 - 0.023 14.3 0.0 0.046 13.4 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA CBM_6 PF03422.15 KXH47802.1 - 0.12 12.6 0.1 25 5.2 0.0 2.3 2 0 0 2 2 2 0 Carbohydrate binding module (family 6) NAD_Gly3P_dh_N PF01210.23 KXH47802.1 - 0.14 12.1 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.15 KXH47802.1 - 0.15 12.2 0.0 0.41 10.8 0.0 1.8 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Lycopene_cycl PF05834.12 KXH47802.1 - 0.16 11.0 0.1 0.29 10.1 0.1 1.5 1 1 0 1 1 1 0 Lycopene cyclase protein Fungal_trans PF04082.18 KXH47803.1 - 8.4e-12 44.7 1.1 1.2e-11 44.2 1.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH47803.1 - 1.2e-08 34.9 10.9 2.9e-08 33.7 10.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_12 PF01670.16 KXH47804.1 - 3e-45 154.8 10.2 3.5e-45 154.6 10.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 Phage_holin_5_1 PF06946.11 KXH47804.1 - 1.2 9.6 8.2 0.3 11.5 1.5 2.7 1 1 1 2 2 2 0 Bacteriophage A118-like holin, Hol118 Bac_luciferase PF00296.20 KXH47805.1 - 1e-59 202.5 0.1 1.4e-59 202.1 0.1 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase MFS_1 PF07690.16 KXH47806.1 - 1.7e-26 93.0 24.7 2e-24 86.2 16.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.18 KXH47835.1 - 9.6e-35 119.9 0.0 1.6e-34 119.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH47836.1 - 2.7e-10 40.2 12.9 4.9e-10 39.4 12.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXH47836.1 - 0.0012 17.9 0.0 0.0025 16.9 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_43 PF04616.14 KXH47837.1 - 6.5e-33 114.3 0.9 8.4e-33 113.9 0.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Cupin_2 PF07883.11 KXH47838.1 - 2.1e-15 56.2 0.5 3e-15 55.7 0.1 1.4 2 0 0 2 2 2 1 Cupin domain AraC_binding PF02311.19 KXH47838.1 - 1.3e-08 34.8 0.0 2.3e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain MannoseP_isomer PF01050.18 KXH47838.1 - 0.0014 18.6 0.0 0.0018 18.2 0.0 1.2 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase Cupin_1 PF00190.22 KXH47838.1 - 0.0019 17.8 0.0 0.0022 17.6 0.0 1.2 1 0 0 1 1 1 1 Cupin DMSP_lyase PF16867.5 KXH47838.1 - 0.0071 16.0 0.0 0.008 15.8 0.0 1.1 1 0 0 1 1 1 1 Dimethlysulfonioproprionate lyase Cupin_3 PF05899.12 KXH47838.1 - 0.024 14.3 0.0 0.043 13.5 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF861) Cupin_7 PF12973.7 KXH47838.1 - 0.079 12.9 0.0 0.18 11.8 0.0 1.7 1 0 0 1 1 1 0 ChrR Cupin-like domain Ectoine_synth PF06339.12 KXH47838.1 - 0.082 13.1 0.0 0.11 12.7 0.0 1.1 1 0 0 1 1 1 0 Ectoine synthase CENP-C_C PF11699.8 KXH47838.1 - 0.1 12.9 0.0 0.13 12.5 0.0 1.2 1 0 0 1 1 1 0 Mif2/CENP-C like Pirin_C PF05726.13 KXH47838.1 - 0.14 12.5 0.0 0.2 12.1 0.0 1.2 1 0 0 1 1 1 0 Pirin C-terminal cupin domain Amidohydro_2 PF04909.14 KXH47839.1 - 8.2e-24 84.9 0.2 9.7e-24 84.6 0.2 1.1 1 0 0 1 1 1 1 Amidohydrolase GMC_oxred_N PF00732.19 KXH47841.1 - 1.8e-48 165.5 0.0 4e-47 161.0 0.0 2.2 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXH47841.1 - 8.7e-06 26.3 0.0 1.4e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KXH47841.1 - 0.00013 21.1 0.2 0.00033 19.8 0.2 1.6 1 1 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 KXH47841.1 - 0.014 15.6 0.0 0.038 14.2 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXH47841.1 - 0.082 12.5 0.0 0.54 9.8 0.0 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.22 KXH47841.1 - 0.086 11.9 0.0 9.7 5.1 0.0 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A Thi4 PF01946.17 KXH47841.1 - 0.12 11.7 0.1 0.22 10.7 0.1 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.14 KXH47841.1 - 0.12 11.6 0.0 0.38 10.0 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DHHC PF01529.20 KXH47842.1 - 0.95 9.6 6.9 2 8.5 0.1 2.7 2 1 0 2 2 2 0 DHHC palmitoyltransferase MFS_1 PF07690.16 KXH47843.1 - 1.2e-27 96.7 32.2 5.9e-19 68.2 17.8 2.9 1 1 1 3 3 3 2 Major Facilitator Superfamily PUCC PF03209.15 KXH47843.1 - 9.7e-05 21.5 1.9 0.0003 19.9 1.9 1.8 1 1 0 1 1 1 1 PUCC protein CheD PF03975.13 KXH47844.1 - 0.07 13.2 2.0 1.4 9.0 0.4 2.7 3 0 0 3 3 3 0 CheD chemotactic sensory transduction DUF3818 PF12825.7 KXH47844.1 - 0.31 10.0 8.4 0.13 11.3 4.4 2.0 2 0 0 2 2 2 0 Domain of unknown function in PX-proteins (DUF3818) WDCP PF15390.6 KXH47844.1 - 3.9 5.7 6.9 3 6.1 5.4 1.5 1 1 0 1 1 1 0 WD repeat and coiled-coil-containing protein family SMBP PF16785.5 KXH47844.1 - 6.8 7.0 8.8 0.36 11.0 0.4 2.7 2 1 1 3 3 3 0 Small metal-binding protein MbeB_N PF04837.12 KXH47844.1 - 9 6.7 9.0 21 5.5 0.1 4.3 3 0 0 3 3 3 0 MbeB-like, N-term conserved region DUF3759 PF12585.8 KXH47845.1 - 5.8e-41 138.4 7.0 7.7e-41 138.0 7.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) ARHGEF5_35 PF15441.6 KXH47845.1 - 0.033 13.2 3.0 0.038 13.0 3.0 1.0 1 0 0 1 1 1 0 Rho guanine nucleotide exchange factor 5/35 MAP7 PF05672.11 KXH47845.1 - 0.056 13.1 4.4 0.064 12.9 4.4 1.1 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family DUF3824 PF12868.7 KXH47845.1 - 0.2 12.3 3.8 1.7 9.3 3.8 2.0 1 1 0 1 1 1 0 Domain of unknwon function (DUF3824) tRNA-synt_1e PF01406.19 KXH47846.1 - 5.9e-112 373.9 0.1 8.7e-112 373.4 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 KXH47846.1 - 1.7e-06 27.0 0.6 0.024 13.4 0.1 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (M) DALR_2 PF09190.11 KXH47846.1 - 0.0073 16.8 0.1 0.0073 16.8 0.1 2.4 2 0 0 2 2 2 1 DALR domain DUF416 PF04222.12 KXH47846.1 - 0.0088 15.5 0.0 0.022 14.2 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF416) DUF1599 PF07659.11 KXH47846.1 - 0.08 13.4 0.1 0.23 11.9 0.1 1.8 1 0 0 1 1 1 0 Nucleotide modification associated domain 1 tRNA-synt_1c PF00749.21 KXH47846.1 - 0.16 10.8 1.0 0.28 10.1 0.0 1.8 2 0 0 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain NARP1 PF12569.8 KXH47846.1 - 0.23 10.3 8.3 10 4.9 8.3 2.3 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 GCD14 PF08704.10 KXH47847.1 - 1.8e-61 208.0 0.0 5.7e-60 203.1 0.0 2.2 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit NMT1 PF09084.11 KXH47848.1 - 0.00038 20.5 0.0 0.0007 19.6 0.0 1.5 1 1 0 1 1 1 1 NMT1/THI5 like SBP_bac_3 PF00497.20 KXH47848.1 - 0.00089 18.8 0.0 0.0057 16.1 0.0 2.1 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 TOPRIM_C PF16898.5 KXH47848.1 - 0.09 13.1 0.1 0.15 12.3 0.1 1.3 1 0 0 1 1 1 0 C-terminal associated domain of TOPRIM T3SS_TC PF06511.11 KXH47848.1 - 0.13 11.6 0.2 0.18 11.1 0.2 1.1 1 0 0 1 1 1 0 Type III secretion systems tip complex components XPG_I_2 PF12813.7 KXH47848.1 - 0.18 11.2 0.1 0.26 10.7 0.1 1.1 1 0 0 1 1 1 0 XPG domain containing CTP_transf_like PF01467.26 KXH47849.1 - 1.6e-05 25.1 0.0 0.00016 21.9 0.0 2.2 2 0 0 2 2 2 1 Cytidylyltransferase-like FAD_syn PF06574.12 KXH47849.1 - 0.04 13.8 0.0 0.063 13.2 0.0 1.3 1 0 0 1 1 1 0 FAD synthetase HET PF06985.11 KXH47850.1 - 6.7e-36 123.8 0.3 1.2e-35 123.1 0.3 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Saf-Nte_pilin PF09460.10 KXH47850.1 - 0.21 11.6 0.1 27 4.7 0.0 2.3 2 0 0 2 2 2 0 Saf-pilin pilus formation protein SLAC1 PF03595.17 KXH47851.1 - 2.3e-85 286.7 38.1 2.6e-85 286.5 38.1 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Peptidase_M13_N PF05649.13 KXH47852.1 - 8.4e-97 325.2 0.0 1.3e-96 324.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 KXH47852.1 - 4.2e-62 209.4 1.1 1.4e-61 207.7 0.2 2.0 2 0 0 2 2 2 1 Peptidase family M13 TFR_dimer PF04253.15 KXH47853.1 - 7.4e-26 90.6 0.0 1.3e-25 89.9 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 KXH47853.1 - 6.6e-21 74.9 0.0 1.2e-20 74.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KXH47853.1 - 4.6e-08 33.0 0.5 3.7e-07 30.1 0.5 2.3 1 1 0 1 1 1 1 PA domain CFEM PF05730.11 KXH47854.1 - 7e-08 32.5 8.9 1.3e-07 31.6 8.9 1.4 1 0 0 1 1 1 1 CFEM domain NPCC PF08058.11 KXH47854.1 - 0.54 10.3 4.4 23 5.0 4.4 2.8 1 1 0 1 1 1 0 Nuclear pore complex component Rootletin PF15035.6 KXH47855.1 - 0.0037 17.3 0.4 0.0058 16.7 0.4 1.2 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion ATF7IP_BD PF16788.5 KXH47855.1 - 0.072 13.2 0.8 0.14 12.2 0.6 1.6 1 1 0 1 1 1 0 ATF-interacting protein binding domain YabA PF06156.13 KXH47855.1 - 0.11 13.1 0.1 0.22 12.2 0.1 1.5 1 0 0 1 1 1 0 Initiation control protein YabA FAD_binding_4 PF01565.23 KXH47856.1 - 2.6e-24 85.6 5.8 6.4e-24 84.3 5.8 1.7 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 KXH47856.1 - 4.7e-13 49.0 0.1 8.8e-13 48.1 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like PIF1 PF05970.14 KXH47858.1 - 1.2e-40 139.9 3.6 2.9e-26 92.5 0.0 4.0 2 1 1 3 3 3 3 PIF1-like helicase AAA_30 PF13604.6 KXH47858.1 - 2e-23 83.1 0.1 9.5e-16 58.1 0.0 3.5 3 0 0 3 3 3 3 AAA domain AAA_19 PF13245.6 KXH47858.1 - 3e-12 47.1 0.1 4.3e-11 43.3 0.1 2.7 2 1 0 2 2 2 1 AAA domain Herpes_Helicase PF02689.14 KXH47858.1 - 2.2e-06 25.9 0.1 0.00024 19.2 0.0 2.1 2 0 0 2 2 2 1 Helicase AAA_22 PF13401.6 KXH47858.1 - 2.3e-06 27.9 0.0 6.1e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KXH47858.1 - 2.4e-06 27.6 0.0 5.5e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Viral_helicase1 PF01443.18 KXH47858.1 - 1.4e-05 24.9 0.2 0.22 11.3 0.2 3.1 2 1 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.6 KXH47858.1 - 7.5e-05 23.2 0.0 0.00023 21.6 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 KXH47858.1 - 0.0013 19.3 0.0 0.005 17.4 0.0 2.0 1 0 0 1 1 1 1 ABC transporter Cauli_VI PF01693.16 KXH47858.1 - 0.0014 18.9 0.5 0.0014 18.9 0.5 3.1 3 0 0 3 3 2 1 Caulimovirus viroplasmin DUF815 PF05673.13 KXH47858.1 - 0.0016 17.7 0.0 0.064 12.4 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_29 PF13555.6 KXH47858.1 - 0.002 17.8 0.0 0.0065 16.2 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain Mg_chelatase PF01078.21 KXH47858.1 - 0.0029 17.0 0.0 0.0055 16.1 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA PF00004.29 KXH47858.1 - 0.003 18.0 0.0 0.0063 16.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Helicase_RecD PF05127.14 KXH47858.1 - 0.0069 16.3 0.0 0.018 14.9 0.0 1.7 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.6 KXH47858.1 - 0.0072 16.1 0.0 0.026 14.4 0.0 1.9 2 0 0 2 2 1 1 UvrD-like helicase C-terminal domain AAA_14 PF13173.6 KXH47858.1 - 0.01 15.8 0.0 0.031 14.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KXH47858.1 - 0.017 15.5 0.0 0.1 13.0 0.0 2.4 1 1 0 1 1 1 0 RNA helicase AAA_28 PF13521.6 KXH47858.1 - 0.021 15.1 0.0 0.047 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KXH47858.1 - 0.022 14.6 0.3 2.8 7.8 0.1 2.4 2 0 0 2 2 2 0 NTPase DUF2075 PF09848.9 KXH47858.1 - 0.034 13.4 0.0 0.065 12.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) T2SSE PF00437.20 KXH47858.1 - 0.051 12.6 0.0 0.17 10.9 0.0 1.7 1 1 0 1 1 1 0 Type II/IV secretion system protein AAA_7 PF12775.7 KXH47858.1 - 0.067 12.7 0.1 0.21 11.1 0.1 1.8 1 1 0 1 1 1 0 P-loop containing dynein motor region RsgA_GTPase PF03193.16 KXH47858.1 - 0.071 13.0 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase IstB_IS21 PF01695.17 KXH47858.1 - 0.082 12.6 0.1 2.6 7.7 0.1 2.5 3 0 0 3 3 2 0 IstB-like ATP binding protein ATPase_2 PF01637.18 KXH47858.1 - 0.099 12.5 0.0 0.25 11.2 0.0 1.7 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea ATP-synt_ab PF00006.25 KXH47858.1 - 0.11 12.2 0.0 0.51 10.0 0.2 1.5 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain DEAD PF00270.29 KXH47858.1 - 0.11 12.2 0.3 0.5 10.1 0.3 2.0 1 1 0 1 1 1 0 DEAD/DEAH box helicase NB-ARC PF00931.22 KXH47858.1 - 0.12 11.6 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain MeaB PF03308.16 KXH47858.1 - 0.17 10.8 0.0 0.34 9.9 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB CMD PF02627.20 KXH47859.1 - 0.0054 16.8 0.0 0.015 15.4 0.0 1.8 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family TPR_12 PF13424.6 KXH47860.1 - 0.00032 20.9 6.7 1.2 9.5 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KXH47860.1 - 0.00087 19.8 8.5 2 9.0 0.4 3.9 2 1 2 4 4 4 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KXH47860.1 - 0.009 16.2 0.9 0.13 12.5 0.3 2.9 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.14 KXH47860.1 - 0.0095 16.5 10.2 0.8 10.5 0.3 5.4 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 KXH47860.1 - 0.11 12.7 7.4 9.5 6.6 0.2 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 KXH47860.1 - 0.13 12.6 0.3 12 6.4 0.0 3.9 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 KXH47860.1 - 0.26 11.4 0.1 0.26 11.4 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 KXH47860.1 - 0.42 11.3 11.7 17 6.2 0.0 4.7 4 2 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 KXH47860.1 - 0.48 11.2 2.5 13 6.6 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KXH47860.1 - 0.64 11.0 11.2 45 5.3 0.1 5.4 3 2 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 KXH47860.1 - 0.9 9.5 9.9 11 6.1 0.1 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat CorA PF01544.18 KXH47861.1 - 0.00036 20.0 1.9 0.00036 20.0 1.9 2.2 2 1 0 2 2 2 1 CorA-like Mg2+ transporter protein 7tm_7 PF08395.12 KXH47861.1 - 0.0088 15.3 0.4 0.017 14.4 0.4 1.4 1 0 0 1 1 1 1 7tm Chemosensory receptor GH131_N PF18271.1 KXH47861.1 - 0.058 13.1 0.1 0.1 12.3 0.1 1.3 1 0 0 1 1 1 0 Glycoside hydrolase 131 catalytic N-terminal domain DUF4974 PF16344.5 KXH47861.1 - 0.15 12.1 1.1 0.49 10.4 0.9 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4974) p450 PF00067.22 KXH47862.1 - 8.6e-45 153.3 0.0 6.1e-30 104.4 0.0 2.5 2 1 0 2 2 2 2 Cytochrome P450 Glyco_hydro_2_C PF02836.17 KXH47863.1 - 6e-90 301.4 0.0 1.6e-89 300.1 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.18 KXH47863.1 - 5.9e-25 88.1 0.0 1.1e-24 87.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.21 KXH47863.1 - 2e-12 47.7 0.2 5.2e-11 43.2 0.1 2.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Cellulase PF00150.18 KXH47863.1 - 0.053 12.9 0.0 0.35 10.3 0.0 2.1 1 1 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) CMD PF02627.20 KXH47863.1 - 0.075 13.1 0.0 0.24 11.5 0.0 1.9 2 0 0 2 2 2 0 Carboxymuconolactone decarboxylase family Methyltransf_23 PF13489.6 KXH47865.1 - 1.8e-18 67.0 0.0 2.8e-18 66.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH47865.1 - 3e-07 30.4 0.1 3.9e-06 26.8 0.1 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH47865.1 - 8.5e-07 29.6 0.0 2.2e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH47865.1 - 1.6e-06 28.7 0.0 1.1e-05 26.0 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH47865.1 - 1.3e-05 25.8 0.0 2.4e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Sugar_tr PF00083.24 KXH47866.1 - 4.7e-71 240.0 29.3 5.4e-71 239.8 29.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH47866.1 - 6.6e-10 38.4 49.1 4.8e-08 32.3 15.8 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KXH47866.1 - 5.5e-06 25.2 20.7 7.5e-05 21.5 4.2 2.7 3 0 0 3 3 3 2 MFS/sugar transport protein MFS_1_like PF12832.7 KXH47866.1 - 5.8e-06 25.4 2.5 5.8e-06 25.4 2.5 2.4 3 0 0 3 3 3 1 MFS_1 like family Mycoplasma_p37 PF06646.11 KXH47867.1 - 0.14 11.4 0.2 0.26 10.5 0.2 1.4 1 0 0 1 1 1 0 High affinity transport system protein p37 FAD_binding_4 PF01565.23 KXH47868.1 - 7.5e-19 67.8 0.2 1.2e-18 67.2 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KXH47868.1 - 5e-13 48.9 0.0 1.1e-12 47.8 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like PEP_mutase PF13714.6 KXH47869.1 - 1.9e-58 197.7 1.0 2.2e-58 197.5 1.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase SGL PF08450.12 KXH47870.1 - 2.7e-06 27.1 0.3 1.1e-05 25.2 0.3 1.8 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Acetyltransf_10 PF13673.7 KXH47873.1 - 5.8e-06 26.3 0.0 8.9e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXH47873.1 - 1e-05 25.7 0.1 2.3e-05 24.6 0.2 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXH47873.1 - 7.6e-05 23.1 0.1 0.00013 22.3 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KXH47873.1 - 0.0019 18.3 0.0 0.015 15.4 0.0 2.3 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Spherulin4 PF12138.8 KXH47874.1 - 3e-41 141.6 2.0 3.7e-41 141.3 2.0 1.0 1 0 0 1 1 1 1 Spherulation-specific family 4 FAD_binding_3 PF01494.19 KXH47875.1 - 3.2e-31 108.9 0.1 7.1e-31 107.7 0.1 1.6 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 KXH47875.1 - 1.6e-07 30.9 0.4 1.1e-06 28.1 0.4 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXH47875.1 - 1.5e-06 28.3 0.4 2.4e-05 24.5 0.2 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KXH47875.1 - 1.4e-05 24.6 0.1 0.072 12.4 0.0 2.8 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 KXH47875.1 - 5e-05 22.7 0.4 0.0003 20.1 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXH47875.1 - 7.2e-05 23.3 0.2 0.002 18.6 0.3 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXH47875.1 - 0.00026 20.2 0.2 0.00059 19.0 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KXH47875.1 - 0.00027 19.7 0.1 0.00059 18.7 0.1 1.5 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.17 KXH47875.1 - 0.0011 18.2 0.0 0.0019 17.5 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Trp_halogenase PF04820.14 KXH47875.1 - 0.0029 16.5 0.3 0.0085 15.0 0.1 1.9 2 0 0 2 2 2 1 Tryptophan halogenase GIDA PF01134.22 KXH47875.1 - 0.0046 16.1 0.5 0.02 14.0 0.1 2.1 3 0 0 3 3 3 1 Glucose inhibited division protein A DAO PF01266.24 KXH47875.1 - 0.0048 16.5 1.3 0.013 15.1 0.9 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KXH47875.1 - 0.0052 15.9 1.4 0.91 8.5 0.1 2.6 3 0 0 3 3 3 2 Lycopene cyclase protein FAD_oxidored PF12831.7 KXH47875.1 - 0.0059 16.0 0.2 0.0059 16.0 0.2 1.7 2 1 0 2 2 2 1 FAD dependent oxidoreductase TrkA_N PF02254.18 KXH47875.1 - 0.029 14.6 0.1 0.076 13.3 0.1 1.7 1 0 0 1 1 1 0 TrkA-N domain AlaDh_PNT_C PF01262.21 KXH47875.1 - 0.084 12.1 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.6 KXH47875.1 - 0.44 10.5 2.9 2.5 8.1 0.3 2.8 3 0 0 3 3 3 0 FAD-NAD(P)-binding CAP PF00188.26 KXH47876.1 - 3.2e-19 70.0 0.6 4.6e-19 69.5 0.6 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Glyco_hydro_18 PF00704.28 KXH47877.1 - 3.8e-67 227.2 0.5 3.8e-67 227.2 0.5 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 KXH47877.1 - 7.6e-12 45.5 31.6 5e-10 39.7 7.0 6.6 10 1 0 10 10 10 2 Chitin recognition protein Pectate_lyase_3 PF12708.7 KXH47878.1 - 2e-91 305.6 9.2 1e-76 257.5 0.2 2.8 3 0 0 3 3 3 2 Pectate lyase superfamily protein LysM PF01476.20 KXH47878.1 - 1.9e-08 34.2 0.0 0.00023 21.2 0.0 3.3 3 0 0 3 3 3 2 LysM domain End_N_terminal PF12218.8 KXH47878.1 - 4.7e-07 29.4 3.8 0.014 15.1 0.3 2.8 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase AAA_lid_11 PF18198.1 KXH47878.1 - 0.14 12.0 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 Dynein heavy chain AAA lid domain p450 PF00067.22 KXH47879.1 - 5.7e-56 190.2 0.0 7.5e-56 189.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_4 PF01565.23 KXH47880.1 - 3.2e-18 65.8 2.0 5.5e-18 65.0 2.0 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KXH47880.1 - 1.5e-07 31.4 0.2 3.4e-07 30.3 0.2 1.6 1 0 0 1 1 1 1 Berberine and berberine like NUDIX PF00293.28 KXH47881.1 - 1.1e-07 31.9 0.0 2e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain DUF4743 PF15916.5 KXH47881.1 - 0.0062 16.5 0.0 0.01 15.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4743) p450 PF00067.22 KXH47883.1 - 1.2e-64 218.8 0.0 1.7e-64 218.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans_2 PF11951.8 KXH47883.1 - 6.6e-11 41.6 2.2 1.1e-10 40.9 2.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain TPP_enzyme_N PF02776.18 KXH47884.1 - 6e-33 113.9 0.3 9.7e-33 113.2 0.3 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KXH47884.1 - 1.2e-19 70.5 0.1 3.1e-17 62.8 0.0 2.4 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KXH47884.1 - 1.6e-18 66.7 0.0 4.6e-18 65.3 0.0 1.8 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain AAL_decarboxy PF03306.13 KXH47886.1 - 3.8e-78 261.8 0.1 4.3e-78 261.6 0.1 1.0 1 0 0 1 1 1 1 Alpha-acetolactate decarboxylase TPP_enzyme_N PF02776.18 KXH47887.1 - 6.1e-46 156.2 1.4 9.8e-46 155.5 0.6 1.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KXH47887.1 - 5.7e-40 136.6 0.1 2.6e-38 131.2 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KXH47887.1 - 6.4e-26 90.7 0.0 1.5e-25 89.6 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain Peptidase_M55 PF04951.13 KXH47887.1 - 0.029 13.8 0.1 0.06 12.7 0.1 1.5 1 0 0 1 1 1 0 D-aminopeptidase GST_N_3 PF13417.6 KXH47888.1 - 6e-15 55.4 0.0 1.1e-14 54.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KXH47888.1 - 7.5e-14 51.8 0.0 1.4e-13 50.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KXH47888.1 - 1.5e-12 47.7 0.0 4e-12 46.3 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 KXH47888.1 - 0.0017 18.5 0.0 0.0035 17.5 0.0 1.6 1 0 0 1 1 1 1 Glutaredoxin GST_C PF00043.25 KXH47888.1 - 0.016 15.4 0.1 0.042 14.1 0.1 1.7 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain dCMP_cyt_deam_1 PF00383.23 KXH47890.1 - 2.4e-09 37.0 0.1 5.2e-09 35.9 0.1 1.5 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KXH47890.1 - 4.6e-05 23.2 0.0 0.00058 19.6 0.0 2.3 2 1 0 2 2 2 1 MafB19-like deaminase Bd3614-deam PF14439.6 KXH47890.1 - 0.77 9.8 3.4 6.9 6.7 3.4 2.1 1 1 0 1 1 1 0 Bd3614-like deaminase DOPA_dioxygen PF08883.11 KXH47891.1 - 6.9e-31 106.6 0.0 8.9e-31 106.2 0.0 1.1 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family DUF3328 PF11807.8 KXH47892.1 - 3.8e-49 167.4 0.1 4.9e-49 167.1 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Tmemb_161AB PF10268.9 KXH47892.1 - 0.0089 14.7 0.2 0.012 14.3 0.2 1.1 1 0 0 1 1 1 1 Predicted transmembrane protein 161AB RHH_7 PF16777.5 KXH47893.1 - 0.0071 16.7 0.1 2.4e+02 2.2 0.0 5.5 1 1 6 7 7 7 0 Transcriptional regulator, RHH-like, CopG DinB_2 PF12867.7 KXH47894.1 - 0.00042 20.8 0.3 0.00066 20.2 0.3 1.4 1 0 0 1 1 1 1 DinB superfamily HET PF06985.11 KXH47895.1 - 3.4e-11 43.7 8.2 7.4e-09 36.1 0.9 3.0 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) DUF3445 PF11927.8 KXH47896.1 - 1.8e-77 260.0 0.0 2.2e-77 259.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) EutQ PF06249.12 KXH47897.1 - 1.5e-12 47.5 0.0 2e-12 47.1 0.0 1.0 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Cupin_3 PF05899.12 KXH47897.1 - 9.3e-10 38.1 0.0 2.6e-09 36.6 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF861) Cupin_2 PF07883.11 KXH47897.1 - 7.2e-05 22.4 0.0 0.0001 21.9 0.0 1.3 1 0 0 1 1 1 1 Cupin domain KduI PF04962.12 KXH47897.1 - 0.046 13.0 0.0 0.051 12.9 0.0 1.1 1 0 0 1 1 1 0 KduI/IolB family Pirin PF02678.16 KXH47897.1 - 0.053 13.5 0.0 0.065 13.2 0.0 1.3 1 0 0 1 1 1 0 Pirin Cupin_1 PF00190.22 KXH47897.1 - 0.1 12.2 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Cupin Cupin_6 PF12852.7 KXH47897.1 - 0.14 11.9 0.0 0.16 11.6 0.0 1.1 1 0 0 1 1 1 0 Cupin Fungal_trans_2 PF11951.8 KXH47898.1 - 2.2e-25 89.3 2.1 1.8e-18 66.5 1.3 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH47898.1 - 5.4e-08 32.8 7.2 8.3e-08 32.2 7.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3445 PF11927.8 KXH47899.1 - 8.2e-73 244.7 0.0 1.1e-72 244.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Ammonium_transp PF00909.21 KXH47900.1 - 7.9e-98 327.8 20.5 9.5e-98 327.5 20.5 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Comm PF15957.5 KXH47900.1 - 0.52 10.7 0.0 0.52 10.7 0.0 2.0 3 0 0 3 3 3 0 Commissureless Gpr1_Fun34_YaaH PF01184.19 KXH47901.1 - 1.9e-27 96.3 17.5 2e-27 96.1 17.5 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Cellulase PF00150.18 KXH47903.1 - 2e-21 76.6 0.3 2.6e-21 76.3 0.3 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.17 KXH47903.1 - 9.4e-08 31.5 0.0 1.4e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_42 PF02449.15 KXH47903.1 - 4.1e-05 23.1 0.1 0.00011 21.7 0.1 1.6 1 0 0 1 1 1 1 Beta-galactosidase DUF4038 PF13204.6 KXH47903.1 - 0.00038 20.2 3.3 0.00079 19.2 3.3 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF4038) Lipase_GDSL_2 PF13472.6 KXH47904.1 - 1.2e-16 61.6 0.0 1.7e-16 61.2 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KXH47904.1 - 4.7e-09 36.5 0.0 7e-09 36.0 0.0 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase OSK PF17182.4 KXH47904.1 - 0.00043 19.6 0.0 0.00061 19.1 0.0 1.2 1 0 0 1 1 1 1 OSK domain Lipase_GDSL_3 PF14606.6 KXH47904.1 - 0.0028 17.8 0.0 0.0039 17.4 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family HET PF06985.11 KXH47905.1 - 3.2e-28 98.9 0.0 6.2e-28 98.0 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SKG6 PF08693.10 KXH47906.1 - 0.0098 15.3 0.7 0.02 14.3 0.7 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain LapA_dom PF06305.11 KXH47906.1 - 0.09 12.6 0.1 0.17 11.8 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain DUF4448 PF14610.6 KXH47906.1 - 0.13 12.1 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Zincin_2 PF10103.9 KXH47907.1 - 0.13 11.5 1.4 0.23 10.7 1.4 1.3 1 0 0 1 1 1 0 Zincin-like metallopeptidase DUF3328 PF11807.8 KXH47910.1 - 3.1e-20 72.9 1.2 4.6e-20 72.4 1.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Methyltransf_23 PF13489.6 KXH47925.1 - 5.3e-19 68.6 0.0 9.5e-19 67.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH47925.1 - 1.1e-09 38.9 0.0 2.1e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH47925.1 - 2.6e-08 33.8 0.0 2.1e-07 30.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH47925.1 - 1.6e-07 31.9 0.0 4.2e-07 30.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH47925.1 - 6.6e-05 23.6 0.1 0.00038 21.1 0.0 2.3 2 1 0 2 2 1 1 Methyltransferase domain PrmA PF06325.13 KXH47925.1 - 0.00015 21.3 0.0 0.00027 20.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 KXH47925.1 - 0.00029 20.3 0.0 0.0095 15.3 0.0 2.1 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KXH47925.1 - 0.002 17.7 0.0 0.0056 16.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.19 KXH47925.1 - 0.0088 16.2 0.0 0.014 15.5 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_4 PF02390.17 KXH47925.1 - 0.021 14.3 0.0 0.056 12.9 0.0 1.7 2 0 0 2 2 2 0 Putative methyltransferase PCMT PF01135.19 KXH47925.1 - 0.041 13.6 0.0 0.072 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF676 PF05057.14 KXH47935.1 - 4e-08 33.0 0.0 7.3e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 KXH47935.1 - 2.6e-07 31.5 0.1 6.9e-07 30.1 0.1 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 KXH47935.1 - 1.3e-06 28.4 0.3 3.9e-05 23.5 0.3 2.4 1 1 0 1 1 1 1 PGAP1-like protein UPF0227 PF05728.12 KXH47935.1 - 0.00045 20.2 0.0 0.0017 18.3 0.1 1.9 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0227) Hydrolase_4 PF12146.8 KXH47935.1 - 0.003 16.8 0.0 0.0064 15.8 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF2974 PF11187.8 KXH47935.1 - 0.0068 16.0 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_3 PF07859.13 KXH47935.1 - 0.0086 16.0 0.0 0.016 15.1 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.20 KXH47935.1 - 0.012 15.8 0.0 0.012 15.8 0.0 2.0 2 0 0 2 2 2 0 Thioesterase domain Lipase_3 PF01764.25 KXH47935.1 - 0.013 15.4 0.0 0.023 14.5 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_1 PF00561.20 KXH47935.1 - 0.016 14.9 0.1 0.039 13.6 0.1 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold LIDHydrolase PF10230.9 KXH47935.1 - 0.11 12.1 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Noggin PF05806.12 KXH47935.1 - 3.8 7.4 11.1 22 4.9 0.0 2.7 2 0 0 2 2 2 0 Noggin Rox3 PF08633.10 KXH47936.1 - 1.6e-63 214.8 0.3 1.6e-63 214.8 0.3 1.4 2 0 0 2 2 2 1 Rox3 mediator complex subunit NIF PF03031.18 KXH47951.1 - 7.5e-54 181.7 0.4 1.1e-53 181.2 0.4 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Sec61_beta PF03911.16 KXH47951.1 - 3.4e-18 65.4 1.9 5.7e-18 64.7 1.9 1.4 1 0 0 1 1 1 1 Sec61beta family Glyco_transf_28 PF03033.20 KXH47952.1 - 4.2e-19 69.0 0.6 1e-10 41.8 0.0 2.4 2 0 0 2 2 2 2 Glycosyltransferase family 28 N-terminal domain ATG_C PF09333.11 KXH47952.1 - 0.00014 22.1 0.0 0.0005 20.4 0.0 1.9 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain UDPGT PF00201.18 KXH47952.1 - 0.00042 19.2 0.0 0.00071 18.5 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase UIM PF02809.20 KXH47952.1 - 0.66 10.0 38.3 1.6 8.9 0.5 6.3 6 0 0 6 6 6 0 Ubiquitin interaction motif NARP1 PF12569.8 KXH47953.1 - 6.1 5.6 8.6 9.3 5.0 8.6 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 PAF-AH_p_II PF03403.13 KXH47954.1 - 8.8e-49 166.0 0.0 7.3e-23 80.7 0.1 3.0 2 1 0 3 3 3 2 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 KXH47954.1 - 6e-08 31.9 0.0 1.9e-06 27.0 0.0 2.2 2 0 0 2 2 2 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 KXH47954.1 - 7.4e-07 28.5 0.0 3.9e-05 22.8 0.0 2.3 2 0 0 2 2 2 1 Chlorophyllase Hydrolase_4 PF12146.8 KXH47954.1 - 5.7e-05 22.5 0.0 0.078 12.2 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KXH47954.1 - 0.032 14.8 0.2 0.16 12.5 0.0 2.2 3 0 0 3 3 3 0 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 KXH47954.1 - 0.098 12.4 0.0 2.9 7.6 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Fungal_trans PF04082.18 KXH47955.1 - 1.6e-11 43.8 0.0 2.6e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain FUSC_2 PF13515.6 KXH47955.1 - 0.15 12.2 0.1 0.32 11.1 0.1 1.5 1 0 0 1 1 1 0 Fusaric acid resistance protein-like KAR9 PF08580.10 KXH47955.1 - 4.1 5.8 8.5 6.6 5.1 8.5 1.2 1 0 0 1 1 1 0 Yeast cortical protein KAR9 COesterase PF00135.28 KXH47957.1 - 2.6e-69 234.5 0.0 1e-61 209.4 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 KXH47957.1 - 8.7e-07 29.0 0.0 1.6e-05 24.9 0.0 2.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold MFS_1 PF07690.16 KXH47958.1 - 3.7e-24 85.3 26.3 3.7e-24 85.3 26.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Vma12 PF11712.8 KXH47958.1 - 0.4 10.7 2.0 1.2 9.2 0.1 2.3 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF2938 PF11158.8 KXH47960.1 - 0.012 15.1 0.2 0.14 11.6 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2938) Fungal_trans PF04082.18 KXH47961.1 - 3.2e-26 92.0 0.5 6.7e-26 90.9 0.5 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH47962.1 - 2.6e-09 37.1 11.5 3.6e-09 36.6 11.5 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Rep_fac-A_C PF08646.10 KXH47962.1 - 0.036 13.8 1.4 0.042 13.6 1.4 1.1 1 0 0 1 1 1 0 Replication factor-A C terminal domain Fer4_2 PF12797.7 KXH47962.1 - 1.1 9.5 6.7 6.2 7.1 1.0 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Dickkopf_N PF04706.12 KXH47962.1 - 8.5 6.9 13.9 5.3 7.6 2.5 2.1 1 1 1 2 2 2 0 Dickkopf N-terminal cysteine-rich region ECH_1 PF00378.20 KXH47963.1 - 3.2e-40 138.0 0.0 5.2e-40 137.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase HMGL-like PF00682.19 KXH47963.1 - 9.8e-40 136.8 0.0 1.5e-39 136.1 0.0 1.3 1 0 0 1 1 1 1 HMGL-like ECH_2 PF16113.5 KXH47963.1 - 1.5e-27 97.0 0.0 2.2e-27 96.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Carboxyl_trans PF01039.22 KXH47964.1 - 8e-97 324.9 0.0 1e-96 324.5 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain AMP-binding PF00501.28 KXH47965.1 - 1.1e-95 320.7 0.0 1.3e-95 320.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXH47965.1 - 8.2e-15 55.5 0.1 2.7e-14 53.9 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain KduI PF04962.12 KXH47965.1 - 0.2 10.9 0.0 0.35 10.1 0.0 1.3 1 0 0 1 1 1 0 KduI/IolB family CPSase_L_D2 PF02786.17 KXH47966.1 - 4.5e-68 228.9 0.0 6.6e-68 228.3 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 KXH47966.1 - 4.7e-41 139.8 0.1 1.3e-40 138.4 0.1 1.8 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KXH47966.1 - 7.3e-27 93.6 0.0 1.3e-26 92.8 0.0 1.4 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain ATP-grasp PF02222.22 KXH47966.1 - 8.2e-12 45.0 0.0 1.9e-11 43.9 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 KXH47966.1 - 5.5e-09 35.9 0.0 1.3e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl PF00364.22 KXH47966.1 - 3e-07 30.2 4.7 9.5e-07 28.6 4.4 2.0 1 1 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_3 PF02655.14 KXH47966.1 - 7.4e-07 29.3 0.0 1.3e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain WH1 PF00568.23 KXH47966.1 - 0.0087 16.0 0.0 0.28 11.2 0.0 2.7 3 0 0 3 3 3 1 WH1 domain SnoaL_2 PF12680.7 KXH47967.1 - 0.017 15.8 0.0 0.024 15.2 0.0 1.3 1 0 0 1 1 1 0 SnoaL-like domain DUF3176 PF11374.8 KXH47968.1 - 6.2e-26 90.7 5.3 6.7e-26 90.6 3.7 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF3176) DUF4389 PF14333.6 KXH47968.1 - 1 9.4 4.0 0.33 10.9 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4389) Fungal_trans_2 PF11951.8 KXH47969.1 - 7.1e-07 28.4 2.0 8.8e-06 24.8 2.0 2.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Methyltransf_11 PF08241.12 KXH47970.1 - 1.9e-16 60.5 0.0 3.2e-16 59.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH47970.1 - 1.4e-15 57.8 0.0 2.2e-15 57.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH47970.1 - 1.1e-10 42.1 0.0 1.8e-10 41.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH47970.1 - 9.5e-08 32.0 0.0 1.5e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXH47970.1 - 5e-07 29.7 0.0 8.1e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXH47970.1 - 0.0011 18.3 0.0 0.0018 17.6 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 KXH47970.1 - 0.035 13.4 0.0 0.1 11.9 0.0 1.7 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase DREV PF05219.12 KXH47970.1 - 0.042 12.9 0.0 0.062 12.4 0.0 1.1 1 0 0 1 1 1 0 DREV methyltransferase MTS PF05175.14 KXH47970.1 - 0.07 12.7 0.0 0.34 10.4 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_8 PF05148.15 KXH47970.1 - 0.13 12.1 0.0 2.3 8.0 0.0 2.1 2 0 0 2 2 2 0 Hypothetical methyltransferase Methyltransf_4 PF02390.17 KXH47970.1 - 0.17 11.3 0.0 17 4.8 0.0 2.2 2 0 0 2 2 2 0 Putative methyltransferase p450 PF00067.22 KXH47972.1 - 6.1e-68 229.7 0.0 6.4e-67 226.3 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 zf-CCHC_4 PF14392.6 KXH47973.1 - 0.18 11.6 9.5 0.73 9.6 2.4 2.6 2 0 0 2 2 2 0 Zinc knuckle Metallophos PF00149.28 KXH47974.1 - 4.9e-10 40.2 2.5 1.1e-09 39.1 2.5 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Glyco_hydro_3_C PF01915.22 KXH47975.1 - 1.8e-63 214.2 0.0 3.5e-63 213.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KXH47975.1 - 1.7e-54 185.3 0.0 2.6e-54 184.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KXH47975.1 - 9.2e-23 80.1 0.0 1.9e-22 79.1 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 KXH47975.1 - 4.8e-22 78.4 0.0 7.6e-22 77.7 0.0 1.3 1 0 0 1 1 1 1 PA14 domain SCA7 PF08313.12 KXH47977.1 - 2.6e-21 75.3 0.0 3.6e-21 74.8 0.0 1.2 1 0 0 1 1 1 1 SCA7, zinc-binding domain gag-asp_proteas PF13975.6 KXH47978.1 - 2.5e-12 47.2 0.0 6.5e-05 23.4 0.0 2.6 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KXH47978.1 - 4.4e-12 46.5 0.0 2.4e-05 24.9 0.0 2.4 2 0 0 2 2 2 2 Aspartyl protease RVP_2 PF08284.11 KXH47978.1 - 2.1e-05 24.3 0.0 0.0046 16.7 0.0 2.2 2 0 0 2 2 2 2 Retroviral aspartyl protease RVP PF00077.20 KXH47978.1 - 0.0059 16.9 0.0 5.8 7.3 0.0 2.4 2 0 0 2 2 2 2 Retroviral aspartyl protease Asp_protease PF09668.10 KXH47978.1 - 0.009 15.8 0.0 4.2 7.2 0.0 2.5 2 1 0 2 2 2 2 Aspartyl protease Cation_efflux PF01545.21 KXH47980.1 - 1.8e-51 174.7 10.6 9.1e-51 172.4 10.6 1.8 1 1 0 1 1 1 1 Cation efflux family Macoilin PF09726.9 KXH47980.1 - 0.0036 15.9 1.0 0.0048 15.5 1.0 1.2 1 0 0 1 1 1 1 Macoilin family Peptidase_M1_N PF17900.1 KXH47981.1 - 1.4e-06 28.6 0.0 0.0025 18.1 0.0 2.6 2 0 0 2 2 2 2 Peptidase M1 N-terminal domain HEAT PF02985.22 KXH47981.1 - 0.18 12.2 0.1 11 6.6 0.0 2.8 2 0 0 2 2 2 0 HEAT repeat SAS4 PF15460.6 KXH47982.1 - 6.1e-32 109.7 0.1 2.2e-31 107.9 0.1 2.0 1 0 0 1 1 1 1 Something about silencing, SAS, complex subunit 4 SDA1 PF05285.12 KXH47982.1 - 0.0019 17.7 10.0 0.0038 16.7 10.0 1.5 1 0 0 1 1 1 1 SDA1 Adaptin_binding PF10199.9 KXH47982.1 - 0.12 12.9 9.5 0.9 10.2 9.6 2.4 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 CDC45 PF02724.14 KXH47982.1 - 0.24 9.6 9.5 0.4 8.9 9.5 1.3 1 0 0 1 1 1 0 CDC45-like protein POX PF07526.11 KXH47982.1 - 1.3 9.6 4.3 8.1 7.0 3.3 2.6 2 1 0 2 2 2 0 Associated with HOX BUD22 PF09073.10 KXH47982.1 - 3.9 6.7 22.8 0.16 11.3 16.4 1.8 2 0 0 2 2 2 0 BUD22 CDP-OH_P_transf PF01066.21 KXH47983.1 - 5.5e-16 59.1 0.3 5.5e-16 59.1 0.3 2.7 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase PX PF00787.24 KXH47986.1 - 1.2e-21 76.8 0.0 1.6e-21 76.4 0.0 1.2 1 0 0 1 1 1 1 PX domain DUF4746 PF15928.5 KXH47986.1 - 0.14 11.5 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) IQ PF00612.27 KXH47987.1 - 0.00022 20.8 1.3 0.00064 19.3 1.3 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif DUF4247 PF14042.6 KXH47987.1 - 0.078 13.7 0.1 0.078 13.7 0.1 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4247) F-box PF00646.33 KXH47988.1 - 0.00013 21.8 0.1 0.00013 21.8 0.1 2.0 2 0 0 2 2 2 1 F-box domain TPP_enzyme_N PF02776.18 KXH47989.1 - 2e-41 141.4 0.0 9.9e-41 139.2 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KXH47989.1 - 1.6e-23 83.2 0.8 1.6e-23 83.2 0.8 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KXH47989.1 - 7.7e-23 80.8 0.0 1.3e-22 80.0 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain Hpr_kinase_N PF02603.16 KXH47989.1 - 0.14 12.2 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 HPr Serine kinase N terminus ABC2_membrane PF01061.24 KXH47990.1 - 3.9e-92 307.4 49.1 5.5e-48 163.2 20.7 2.5 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 KXH47990.1 - 2.3e-35 122.1 0.0 5.6e-16 59.3 0.0 3.3 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.12 KXH47990.1 - 1.7e-34 117.5 4.1 1.4e-31 108.2 0.1 3.5 3 0 0 3 3 3 2 CDR ABC transporter ABC_trans_N PF14510.6 KXH47990.1 - 8.8e-15 55.1 0.1 2.2e-14 53.8 0.1 1.7 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 KXH47990.1 - 3.1e-07 30.9 0.4 0.00012 22.5 0.2 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 KXH47990.1 - 1.2e-05 25.0 0.0 0.00022 20.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KXH47990.1 - 2.2e-05 24.4 0.0 0.0016 18.4 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_21 PF13304.6 KXH47990.1 - 0.00019 21.3 0.0 1.3 8.8 0.0 3.1 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KXH47990.1 - 0.00023 20.8 0.3 0.036 13.8 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_33 PF13671.6 KXH47990.1 - 0.00057 20.1 0.1 0.078 13.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KXH47990.1 - 0.00061 20.3 0.0 0.12 13.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KXH47990.1 - 0.003 17.3 0.2 0.21 11.3 0.1 2.3 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 KXH47990.1 - 0.0037 16.7 0.0 2.8 7.3 0.0 3.7 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KXH47990.1 - 0.0041 17.4 0.1 0.66 10.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 KXH47990.1 - 0.0065 16.1 0.6 0.11 12.1 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 KXH47990.1 - 0.0076 16.2 0.0 2.3 8.1 0.1 2.6 2 0 0 2 2 2 1 NACHT domain AAA_17 PF13207.6 KXH47990.1 - 0.013 15.9 0.6 3.8 7.9 0.0 3.0 4 0 0 4 4 2 0 AAA domain AAA PF00004.29 KXH47990.1 - 0.034 14.6 0.0 6.5 7.2 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 KXH47990.1 - 0.063 13.8 0.0 0.18 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 KXH47990.1 - 0.19 11.5 0.0 3.6 7.3 0.0 2.2 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase ABC2_membrane_3 PF12698.7 KXH47990.1 - 1.2 8.2 42.9 0.0049 16.0 14.2 3.2 2 1 0 2 2 2 0 ABC-2 family transporter protein HET PF06985.11 KXH47991.1 - 1.4e-33 116.3 0.2 2.5e-33 115.5 0.2 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MotY_N PF18393.1 KXH47991.1 - 0.17 12.0 0.0 0.35 11.0 0.0 1.4 1 0 0 1 1 1 0 MotY N-terminal domain DUF1294 PF06961.13 KXH47992.1 - 0.17 12.2 0.0 1.4 9.2 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1294) adh_short PF00106.25 KXH47994.1 - 1.1e-39 136.0 0.0 1.5e-39 135.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXH47994.1 - 6.8e-28 97.8 0.4 9e-28 97.4 0.4 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 KXH47994.1 - 8e-09 35.7 0.8 1.5e-08 34.8 0.7 1.8 1 1 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 KXH47994.1 - 7.7e-07 29.2 0.2 1.5e-06 28.3 0.1 1.5 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KXH47994.1 - 2.4e-05 23.9 0.0 3.6e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KXH47994.1 - 0.0027 17.3 0.2 0.0047 16.5 0.2 1.4 1 0 0 1 1 1 1 NmrA-like family DUF1776 PF08643.10 KXH47994.1 - 0.0064 15.9 0.0 0.0078 15.6 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) ADH_zinc_N PF00107.26 KXH47994.1 - 0.0073 16.3 0.3 0.02 14.9 0.3 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DFP PF04127.15 KXH47994.1 - 0.032 14.1 0.1 0.051 13.4 0.1 1.3 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein ATPgrasp_N PF18130.1 KXH47994.1 - 0.061 13.9 0.1 0.16 12.5 0.1 1.7 1 0 0 1 1 1 0 ATP-grasp N-terminal domain DASH_Duo1 PF08651.10 KXH47994.1 - 0.079 12.7 0.0 0.28 11.0 0.0 1.9 2 0 0 2 2 2 0 DASH complex subunit Duo1 Peptidase_M28 PF04389.17 KXH47995.1 - 9.6e-35 120.1 0.0 1.2e-34 119.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M28 Ribophorin_II PF05817.14 KXH47996.1 - 5.4e-33 114.5 0.0 6.6e-33 114.2 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II Cep57_CLD_2 PF14197.6 KXH47998.1 - 6.6e-30 103.0 16.3 1.8e-17 63.2 4.8 5.9 4 1 0 5 5 5 2 Centrosome localisation domain of PPC89 Cep57_MT_bd PF06657.13 KXH47998.1 - 2.4e-28 98.4 0.3 2.4e-28 98.4 0.3 6.7 7 1 0 7 7 7 1 Centrosome microtubule-binding domain of Cep57 ATG16 PF08614.11 KXH47998.1 - 1.4e-05 25.4 35.0 1.4e-05 25.4 35.0 6.9 5 2 2 7 7 7 1 Autophagy protein 16 (ATG16) MLD PF11647.8 KXH47998.1 - 0.033 14.4 0.1 0.2 11.9 0.1 2.4 1 0 0 1 1 1 0 Membrane Localization Domain DUF730 PF05325.11 KXH47998.1 - 0.6 10.1 9.0 0.065 13.3 0.6 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF730) Pox_A_type_inc PF04508.12 KXH47998.1 - 4.1 7.4 6.8 1.5 8.8 0.0 3.5 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat NmrA PF05368.13 KXH47999.1 - 1.4e-05 24.8 0.0 2.1e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXH47999.1 - 0.00013 21.9 0.0 0.00024 21.1 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Glyco_transf_4 PF13439.6 KXH47999.1 - 0.049 13.6 0.0 0.077 13.0 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase Family 4 ApbA PF02558.16 KXH47999.1 - 0.2 11.3 0.0 0.32 10.6 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Fungal_trans_2 PF11951.8 KXH48000.1 - 7.8e-21 74.3 4.1 1.2e-10 40.8 1.2 2.0 2 0 0 2 2 2 2 Fungal specific transcription factor domain An_peroxidase PF03098.15 KXH48001.1 - 3e-122 408.9 0.0 3.8e-122 408.6 0.0 1.0 1 0 0 1 1 1 1 Animal haem peroxidase RRM_1 PF00076.22 KXH48002.1 - 3.8e-13 49.0 0.0 5.8e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KXH48002.1 - 0.0049 16.9 0.0 0.0081 16.2 0.0 1.4 1 0 0 1 1 1 1 RNA binding motif PhoD PF09423.10 KXH48003.1 - 3.4e-08 32.9 0.0 6.4e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 PhoD-like phosphatase NAD_binding_4 PF07993.12 KXH48052.1 - 6.8e-36 123.8 0.0 1.1e-35 123.1 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 KXH48052.1 - 1e-32 113.3 0.0 1.5e-32 112.7 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 KXH48052.1 - 1.8e-12 47.3 0.0 4.4e-12 46.0 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KXH48052.1 - 5.2e-07 29.9 0.0 1.1e-06 28.9 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site GDP_Man_Dehyd PF16363.5 KXH48052.1 - 0.0039 16.7 0.0 0.033 13.6 0.0 2.0 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KXH48052.1 - 0.0075 15.3 0.0 0.14 11.2 0.0 2.0 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 KXH48052.1 - 0.0088 16.0 0.1 0.02 14.8 0.1 1.6 1 1 0 1 1 1 1 KR domain Semialdhyde_dh PF01118.24 KXH48052.1 - 0.12 12.8 0.0 0.42 11.1 0.0 2.0 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain AMP-binding_C PF13193.6 KXH48052.1 - 0.15 13.1 0.3 0.67 11.0 0.1 2.2 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain Dak1 PF02733.17 KXH48053.1 - 1.2e-108 362.7 1.3 1.8e-108 362.1 1.3 1.2 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 KXH48053.1 - 3.9e-46 157.1 5.0 9.1e-46 155.9 5.0 1.7 1 0 0 1 1 1 1 DAK2 domain Fungal_trans PF04082.18 KXH48054.1 - 1.4e-28 99.7 0.2 2.2e-28 99.1 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH48054.1 - 9e-08 32.1 9.8 9e-08 32.1 9.8 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 KXH48055.1 - 2.1e-35 122.3 24.0 2.1e-35 122.3 24.0 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Cyclase PF04199.13 KXH48055.1 - 1.3e-09 38.4 0.0 2.2e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 Putative cyclase MFS_4 PF06779.14 KXH48055.1 - 6e-08 32.4 2.8 6e-08 32.4 2.8 1.7 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB DHDPS PF00701.22 KXH48056.1 - 7.7e-29 100.3 0.0 9.4e-29 100.0 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family DUF818 PF05677.12 KXH48056.1 - 0.075 12.0 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) Aldo_ket_red PF00248.21 KXH48057.1 - 1.1e-55 188.9 0.1 8.1e-55 186.1 0.1 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family MR_MLE_C PF13378.6 KXH48058.1 - 8.6e-62 208.6 0.1 1.2e-61 208.1 0.1 1.1 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 KXH48058.1 - 1.8e-16 60.4 0.0 4.1e-16 59.2 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Amidohydro_2 PF04909.14 KXH48058.1 - 0.05 13.4 0.2 0.18 11.5 0.1 1.8 2 0 0 2 2 2 0 Amidohydrolase Glyco_hyd_65N_2 PF14498.6 KXH48059.1 - 0.11 12.3 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain Citrate_synt PF00285.21 KXH48060.1 - 8.6e-123 410.0 0.0 1.1e-122 409.6 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain NmrA PF05368.13 KXH48061.1 - 3.4e-23 82.4 1.3 1.1e-22 80.8 1.3 1.7 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXH48061.1 - 7.8e-19 68.3 2.1 1.4e-18 67.4 0.5 2.1 2 1 0 2 2 2 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KXH48061.1 - 5.3e-10 39.7 3.5 3.4e-08 33.8 0.0 2.8 2 1 1 3 3 3 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 KXH48061.1 - 1.4e-08 34.5 0.0 2.9e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.20 KXH48061.1 - 2.3e-06 27.7 1.8 0.0001 22.4 0.1 2.8 3 0 0 3 3 3 1 Dihydrodipicolinate reductase, N-terminus RmlD_sub_bind PF04321.17 KXH48061.1 - 1.1e-05 24.8 0.3 4.5e-05 22.7 0.1 1.8 2 0 0 2 2 2 1 RmlD substrate binding domain 3HCDH_N PF02737.18 KXH48061.1 - 1.6e-05 24.9 0.2 1.6e-05 24.9 0.2 1.9 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.24 KXH48061.1 - 3.4e-05 24.3 2.6 5.8e-05 23.5 0.1 2.5 3 0 0 3 3 3 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 KXH48061.1 - 6.4e-05 23.2 0.4 0.0023 18.1 0.0 2.4 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase DFP PF04127.15 KXH48061.1 - 6.9e-05 22.8 1.1 0.00055 19.8 0.2 2.2 2 0 0 2 2 2 1 DNA / pantothenate metabolism flavoprotein Shikimate_DH PF01488.20 KXH48061.1 - 0.00017 21.7 0.2 0.00047 20.2 0.0 1.7 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase GDP_Man_Dehyd PF16363.5 KXH48061.1 - 0.00045 19.7 0.4 0.00086 18.8 0.0 1.6 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KXH48061.1 - 0.00046 19.3 0.6 0.0013 17.8 0.0 2.0 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family F420_oxidored PF03807.17 KXH48061.1 - 0.00052 20.5 1.4 0.0011 19.6 0.1 2.1 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.18 KXH48061.1 - 0.0034 17.6 0.1 0.0093 16.2 0.1 1.7 1 0 0 1 1 1 1 TrkA-N domain ApbA PF02558.16 KXH48061.1 - 0.0053 16.4 0.0 0.024 14.3 0.0 2.0 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA adh_short PF00106.25 KXH48061.1 - 0.0057 16.1 2.8 0.0062 16.0 0.2 2.0 2 0 0 2 2 2 1 short chain dehydrogenase IlvN PF07991.12 KXH48061.1 - 0.0062 16.1 0.2 0.015 14.8 0.2 1.6 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain Ldh_1_N PF00056.23 KXH48061.1 - 0.012 15.7 0.3 0.091 12.9 0.1 2.2 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 KXH48061.1 - 0.029 13.7 0.0 0.059 12.7 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Cation_ATPase_C PF00689.21 KXH48062.1 - 1.4e-40 139.0 4.6 1.4e-40 139.0 4.6 2.5 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KXH48062.1 - 1.2e-37 129.2 2.5 1.2e-37 129.2 2.5 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 KXH48062.1 - 1.2e-20 73.3 0.1 3.1e-20 72.0 0.0 1.7 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KXH48062.1 - 1.5e-17 64.6 0.0 1.8e-16 61.1 0.0 2.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KXH48062.1 - 4e-09 36.0 0.2 4.9e-08 32.5 0.0 2.6 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KXH48062.1 - 8.6e-06 25.7 0.2 0.0001 22.2 0.6 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF1295 PF06966.12 KXH48062.1 - 0.034 13.6 0.3 0.43 10.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1295) Abhydrolase_3 PF07859.13 KXH48064.1 - 1.3e-52 178.7 0.0 1.8e-52 178.3 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KXH48064.1 - 0.00042 19.9 0.0 0.041 13.3 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 KXH48064.1 - 0.0015 19.2 0.4 0.0028 18.3 0.2 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.9 KXH48064.1 - 0.0045 16.5 0.1 0.0067 16.0 0.1 1.2 1 0 0 1 1 1 1 Esterase PHB depolymerase COesterase PF00135.28 KXH48064.1 - 0.11 11.3 0.1 0.26 10.1 0.1 1.6 1 1 0 1 1 1 0 Carboxylesterase family PTR2 PF00854.21 KXH48065.1 - 3e-75 253.5 12.5 4.2e-75 253.0 12.5 1.2 1 0 0 1 1 1 1 POT family DUF872 PF05915.12 KXH48065.1 - 1.1 9.5 5.6 2.7 8.2 0.7 2.5 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) TMEM171 PF15471.6 KXH48066.1 - 0.74 8.7 3.1 1.3 8.0 3.1 1.4 1 0 0 1 1 1 0 Transmembrane protein family 171 Pex14_N PF04695.13 KXH48066.1 - 3.4 8.3 13.5 2.3 8.9 0.2 2.4 2 1 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region p450 PF00067.22 KXH48067.1 - 1.6e-67 228.3 0.0 1.8e-67 228.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 TauD PF02668.16 KXH48069.1 - 3.4e-19 69.7 0.4 7.3e-16 58.8 0.3 3.6 1 1 1 2 2 2 2 Taurine catabolism dioxygenase TauD, TfdA family BAR_2 PF10455.9 KXH48077.1 - 0.024 13.8 0.1 0.051 12.7 0.1 1.4 1 0 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking MFS_1 PF07690.16 KXH48078.1 - 1.4e-31 109.7 43.8 3.4e-30 105.2 23.6 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH48078.1 - 2.1e-30 106.0 22.3 2.1e-28 99.4 22.3 2.5 1 1 0 1 1 1 1 Sugar (and other) transporter ThrE PF06738.12 KXH48081.1 - 3.1e-66 223.2 4.5 3.1e-66 223.2 4.5 2.5 3 0 0 3 3 3 2 Putative threonine/serine exporter ThrE_2 PF12821.7 KXH48081.1 - 5.1e-06 26.7 25.0 5.3e-05 23.4 0.6 4.1 4 0 0 4 4 4 3 Threonine/Serine exporter, ThrE NPR2 PF06218.11 KXH48081.1 - 0.21 10.3 0.0 0.32 9.7 0.0 1.2 1 0 0 1 1 1 0 Nitrogen permease regulator 2 Clr5 PF14420.6 KXH48083.1 - 2.3e-15 56.5 5.0 9.9e-15 54.5 5.0 2.2 1 0 0 1 1 1 1 Clr5 domain TPR_12 PF13424.6 KXH48083.1 - 4.1e-08 33.4 2.2 0.0032 17.7 0.0 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat AAA PF00004.29 KXH48084.1 - 0.034 14.6 0.7 0.08 13.4 0.7 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KXH48084.1 - 0.041 14.3 0.2 0.096 13.1 0.2 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 KXH48084.1 - 0.14 12.4 1.0 0.42 10.9 1.0 1.8 1 0 0 1 1 1 0 AAA domain MS_channel PF00924.18 KXH48093.1 - 1.7e-15 57.2 0.4 2.2e-15 56.7 0.4 1.2 1 0 0 1 1 1 1 Mechanosensitive ion channel DLH PF01738.18 KXH48094.1 - 2.7e-23 82.7 0.0 3.8e-23 82.2 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abp2 PF09441.10 KXH48095.1 - 2.6e-88 294.5 0.0 3.8e-88 294.0 0.0 1.2 1 0 0 1 1 1 1 ARS binding protein 2 Sds3 PF08598.11 KXH48097.1 - 2e-23 83.6 11.4 3.2e-23 82.9 11.4 1.5 1 1 0 1 1 1 1 Sds3-like COG5 PF10392.9 KXH48098.1 - 0.0021 18.2 0.6 0.053 13.7 0.0 3.1 3 1 0 3 3 3 1 Golgi transport complex subunit 5 DUF812 PF05667.11 KXH48098.1 - 0.019 13.9 1.9 0.021 13.7 1.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) COG7 PF10191.9 KXH48098.1 - 0.033 12.4 0.0 0.072 11.3 0.0 1.5 1 0 0 1 1 1 0 Golgi complex component 7 (COG7) DUF4795 PF16043.5 KXH48098.1 - 0.054 13.1 2.9 0.06 13.0 0.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) TPPII_N PF12583.8 KXH48098.1 - 0.11 13.1 0.3 0.27 11.8 0.3 1.6 1 0 0 1 1 1 0 Tripeptidyl peptidase II N terminal DUF2040 PF09745.9 KXH48098.1 - 0.12 12.5 1.7 3.9 7.6 1.2 2.4 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 55 (DUF2040) SLAC1 PF03595.17 KXH48099.1 - 2.7e-56 191.2 39.2 3.8e-56 190.7 39.2 1.2 1 0 0 1 1 1 1 Voltage-dependent anion channel DUF5056 PF16479.5 KXH48099.1 - 0.052 13.8 0.2 0.14 12.4 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF5056) Ribosomal_S5_C PF03719.15 KXH48102.1 - 7.1e-22 76.6 0.2 7.7e-21 73.3 0.0 2.7 4 0 0 4 4 4 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 KXH48102.1 - 2.2e-18 66.0 1.1 9.5e-18 63.9 0.4 2.2 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain DASH_Dad3 PF08656.10 KXH48103.1 - 1.1e-33 115.1 0.5 1.3e-33 114.9 0.5 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad3 CorA PF01544.18 KXH48104.1 - 0.00095 18.6 0.0 0.0016 17.8 0.0 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein PARP PF00644.20 KXH48105.1 - 2.1e-14 53.6 0.1 5.3e-14 52.3 0.1 1.7 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain UQ_con PF00179.26 KXH48105.1 - 1.2e-05 25.0 0.0 3.1e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Pkinase PF00069.25 KXH48106.1 - 6.3e-75 251.9 0.0 8.5e-75 251.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXH48106.1 - 1.2e-30 106.6 0.0 5.8e-22 78.2 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KXH48106.1 - 1.5e-06 27.8 0.1 0.88 8.8 0.0 3.1 3 0 0 3 3 3 3 Kinase-like Pkinase_fungal PF17667.1 KXH48106.1 - 0.012 14.4 0.0 0.021 13.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 KXH48106.1 - 0.036 13.4 0.0 0.059 12.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXH48106.1 - 0.066 13.1 0.0 1.6 8.6 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family FOXP-CC PF16159.5 KXH48107.1 - 0.009 16.6 4.5 0.056 14.1 4.0 2.1 1 1 1 2 2 2 1 FOXP coiled-coil domain adh_short PF00106.25 KXH48108.1 - 6.1e-25 87.8 0.0 7.9e-25 87.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXH48108.1 - 7.2e-22 78.1 0.0 9.3e-22 77.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH48108.1 - 0.00072 19.5 0.0 0.0014 18.6 0.0 1.3 1 1 0 1 1 1 1 KR domain ABC_sub_bind PF04392.12 KXH48108.1 - 0.024 13.9 0.0 0.053 12.7 0.0 1.5 2 0 0 2 2 2 0 ABC transporter substrate binding protein CoA_binding_2 PF13380.6 KXH48108.1 - 0.11 13.0 0.0 0.18 12.3 0.0 1.3 1 0 0 1 1 1 0 CoA binding domain DFRP_C PF16543.5 KXH48109.1 - 3.5e-25 88.3 12.1 3.5e-25 88.3 12.1 3.7 3 0 0 3 3 3 1 DRG Family Regulatory Proteins, Tma46 zf-CCCH PF00642.24 KXH48109.1 - 3.3e-06 26.8 8.8 1.7e-05 24.6 2.0 2.9 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KXH48109.1 - 3.1e-05 23.6 11.5 0.0035 17.1 4.1 3.3 3 0 0 3 3 3 2 CCCH-type zinc finger Torus PF16131.5 KXH48109.1 - 4e-05 24.3 18.9 4.5e-05 24.1 5.2 3.6 2 1 1 3 3 3 2 Torus domain zf_CCCH_4 PF18345.1 KXH48109.1 - 0.00047 20.1 8.9 0.00047 20.1 8.9 3.2 3 0 0 3 3 3 2 Zinc finger domain zf-CCCH_3 PF15663.5 KXH48109.1 - 0.0016 18.6 2.4 0.04 14.1 1.1 2.6 2 0 0 2 2 2 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 KXH48109.1 - 2 9.0 17.5 1.2 9.7 7.6 2.9 2 1 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Ost4 PF10215.9 KXH48110.1 - 5.2e-21 74.2 1.2 5.4e-19 67.7 0.6 2.1 2 0 0 2 2 2 2 Oligosaccaryltransferase CS PF04969.16 KXH48111.1 - 4.6e-10 40.4 0.0 7.2e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 CS domain Snf7 PF03357.21 KXH48112.1 - 2.2e-24 86.0 13.4 2.2e-24 86.0 13.4 1.9 2 0 0 2 2 2 1 Snf7 TPR_MLP1_2 PF07926.12 KXH48112.1 - 0.16 12.1 14.3 0.18 11.8 8.2 2.6 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Fib_alpha PF08702.10 KXH48112.1 - 0.77 9.9 8.0 0.59 10.3 5.6 1.9 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family SnoaL_4 PF13577.6 KXH48113.1 - 2.4e-14 53.6 1.8 3.1e-14 53.2 1.8 1.0 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 KXH48113.1 - 0.0069 16.8 2.1 0.011 16.1 2.1 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4440) Scytalone_dh PF02982.14 KXH48113.1 - 0.017 15.0 0.9 0.051 13.4 0.9 1.7 1 1 0 1 1 1 0 Scytalone dehydratase LPMO_10 PF03067.15 KXH48115.1 - 0.098 13.3 0.3 0.13 12.9 0.3 1.2 1 0 0 1 1 1 0 Lytic polysaccharide mono-oxygenase, cellulose-degrading Wap1 PF16997.5 KXH48208.1 - 0.083 12.0 0.0 0.11 11.7 0.0 1.1 1 0 0 1 1 1 0 Wap1 domain Glyco_hydro_3_C PF01915.22 KXH48227.1 - 3.2e-48 164.4 0.0 5.2e-48 163.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 KXH48227.1 - 1.7e-24 85.7 0.1 3.1e-24 84.9 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Glyco_hydro_3 PF00933.21 KXH48227.1 - 1.1e-22 80.8 0.0 2.6e-22 79.6 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain ABC_membrane PF00664.23 KXH48228.1 - 6.3e-43 147.4 14.5 7.8e-43 147.1 14.5 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KXH48228.1 - 1.2e-32 113.3 0.0 2.3e-32 112.4 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 KXH48228.1 - 3.5e-06 27.5 0.0 7.3e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 KXH48228.1 - 0.00022 20.7 0.0 0.052 13.0 0.0 2.2 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KXH48228.1 - 0.00034 20.9 0.1 0.0016 18.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 KXH48228.1 - 0.0034 17.4 0.0 0.025 14.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KXH48228.1 - 0.0042 17.0 0.0 0.013 15.4 0.0 1.7 2 0 0 2 2 2 1 RsgA GTPase AAA_21 PF13304.6 KXH48228.1 - 0.0051 16.7 0.1 0.14 11.9 0.0 2.3 1 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 KXH48228.1 - 0.0059 16.7 0.0 0.018 15.1 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_33 PF13671.6 KXH48228.1 - 0.018 15.2 0.0 0.048 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KXH48228.1 - 0.023 15.1 0.0 0.11 12.9 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 KXH48228.1 - 0.027 14.1 0.0 0.064 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KXH48228.1 - 0.03 14.1 0.0 0.1 12.4 0.0 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 KXH48228.1 - 0.041 13.4 0.0 0.095 12.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_28 PF13521.6 KXH48228.1 - 0.073 13.3 0.0 0.2 11.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 KXH48228.1 - 0.083 12.8 0.1 0.18 11.7 0.1 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_18 PF13238.6 KXH48228.1 - 0.084 13.4 0.0 0.24 12.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 KXH48228.1 - 0.096 12.9 0.4 2.1 8.6 0.4 2.6 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit RNA_helicase PF00910.22 KXH48228.1 - 0.15 12.5 0.0 0.52 10.7 0.0 1.9 2 0 0 2 2 1 0 RNA helicase NACHT PF05729.12 KXH48228.1 - 0.16 11.9 0.3 0.5 10.3 0.0 2.0 3 0 0 3 3 2 0 NACHT domain NB-ARC PF00931.22 KXH48228.1 - 0.18 11.0 0.0 0.32 10.1 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Septin PF00735.18 KXH48228.1 - 0.19 11.0 0.0 0.32 10.2 0.0 1.3 1 0 0 1 1 1 0 Septin DdrB PF12747.7 KXH48229.1 - 0.073 12.9 0.1 1.4 8.7 0.0 2.1 1 1 0 2 2 2 0 DdrB-like protein NAD_binding_10 PF13460.6 KXH48230.1 - 5.2e-08 33.0 0.0 8.1e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KXH48230.1 - 2.7e-07 30.3 0.3 7e-07 28.9 0.1 1.8 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXH48230.1 - 3.8e-06 26.1 0.0 5.9e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 KXH48230.1 - 3.6e-05 23.4 0.1 6e-05 22.7 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family GDP_Man_Dehyd PF16363.5 KXH48230.1 - 0.00035 20.1 0.1 0.00065 19.2 0.0 1.5 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 KXH48230.1 - 0.0092 15.5 0.0 0.058 12.8 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_4 PF07993.12 KXH48230.1 - 0.026 13.7 0.0 1.5 7.9 0.0 2.2 2 0 0 2 2 2 0 Male sterility protein p450 PF00067.22 KXH48231.1 - 7.2e-18 64.6 0.1 1.2e-12 47.3 0.0 3.0 3 0 0 3 3 3 2 Cytochrome P450 YpzI PF14140.6 KXH48232.1 - 8.2 6.3 8.5 50 3.8 0.5 3.5 3 0 0 3 3 3 0 YpzI-like protein RnlA_toxin PF15935.5 KXH48233.1 - 0.0038 17.0 0.1 0.0063 16.3 0.1 1.2 1 0 0 1 1 1 1 RNase LS, bacterial toxin DUF4646 PF15496.6 KXH48233.1 - 0.0053 17.4 0.0 0.2 12.3 0.0 2.5 1 1 1 2 2 2 1 Domain of unknown function (DUF4646) Sugar_tr PF00083.24 KXH48234.1 - 4.6e-82 276.3 19.5 5e-82 276.2 19.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH48234.1 - 1.3e-30 106.5 38.7 1.1e-27 96.9 12.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KXH48234.1 - 3.8e-09 35.5 0.4 5.9e-09 34.9 0.4 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_4 PF06779.14 KXH48234.1 - 5.6e-09 35.8 4.1 5.6e-09 35.8 4.1 1.8 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB DUF1479 PF07350.12 KXH48235.1 - 1.5e-119 399.4 0.0 1.9e-119 399.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) Zn_clus PF00172.18 KXH48236.1 - 3.9e-05 23.7 13.9 8.5e-05 22.6 13.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXH48236.1 - 0.0014 17.7 0.0 0.0024 17.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cep3 PF16846.5 KXH48236.1 - 0.0036 15.9 0.0 0.0097 14.4 0.0 1.6 2 0 0 2 2 2 1 Centromere DNA-binding protein complex CBF3 subunit B Amidohydro_1 PF01979.20 KXH48237.1 - 3.5e-61 207.4 0.0 4.1e-61 207.2 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KXH48237.1 - 3.7e-14 53.1 0.0 1.3e-10 41.4 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family A_deaminase PF00962.22 KXH48237.1 - 0.013 14.8 0.0 0.025 13.9 0.0 1.4 1 0 0 1 1 1 0 Adenosine/AMP deaminase YlbD_coat PF14071.6 KXH48237.1 - 0.047 13.9 0.0 1.7 8.9 0.0 2.4 2 0 0 2 2 2 0 Putative coat protein Abhydrolase_1 PF00561.20 KXH48238.1 - 5.7e-24 85.1 0.1 7.6e-23 81.5 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXH48238.1 - 2.6e-15 57.7 0.5 3.2e-15 57.3 0.5 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXH48238.1 - 9.3e-14 51.3 0.0 6.6e-13 48.5 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KXH48238.1 - 2.6e-06 27.0 0.0 0.055 12.9 0.0 2.4 3 0 0 3 3 3 2 Prolyl oligopeptidase family Abhydrolase_4 PF08386.10 KXH48238.1 - 9.5e-05 22.5 0.0 0.00016 21.7 0.0 1.3 1 0 0 1 1 1 1 TAP-like protein Peptidase_S15 PF02129.18 KXH48238.1 - 0.0012 18.5 0.0 0.0022 17.6 0.0 1.4 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Esterase PF00756.20 KXH48238.1 - 0.026 14.2 0.1 0.051 13.2 0.1 1.6 2 1 0 2 2 2 0 Putative esterase Ndr PF03096.14 KXH48238.1 - 0.1 11.3 0.0 1.2 7.8 0.0 2.3 3 0 0 3 3 3 0 Ndr family DUF3575 PF12099.8 KXH48239.1 - 0.16 11.3 1.8 0.64 9.3 0.1 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3575) Peptidase_S8 PF00082.22 KXH48240.1 - 1.5e-25 90.1 7.2 1.8e-25 89.8 7.2 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 KXH48240.1 - 3.3e-11 43.7 0.1 5.5e-11 43.0 0.1 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 ADH_N PF08240.12 KXH48241.1 - 2.2e-28 98.3 0.3 4.8e-28 97.2 0.3 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXH48241.1 - 2.3e-10 40.6 0.5 4.5e-10 39.6 0.1 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.6 KXH48241.1 - 1.7e-06 27.8 0.1 4.4e-06 26.5 0.1 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated Glu_dehyd_C PF16912.5 KXH48241.1 - 3.4e-06 26.7 0.0 0.00014 21.4 0.0 2.3 2 0 0 2 2 2 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 KXH48241.1 - 0.00031 20.1 0.2 0.0007 19.0 0.2 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 KXH48241.1 - 0.0018 17.0 0.1 0.0055 15.5 0.0 1.7 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 KXH48241.1 - 0.038 14.6 0.3 0.31 11.6 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXH48241.1 - 0.046 12.8 0.1 0.072 12.2 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain TrkA_N PF02254.18 KXH48241.1 - 0.048 13.9 0.0 0.083 13.2 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain FAD_binding_3 PF01494.19 KXH48241.1 - 0.064 12.5 0.1 0.097 11.9 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain zf-RING_2 PF13639.6 KXH48250.1 - 1.5e-12 47.7 5.1 2.3e-12 47.1 5.1 1.3 1 0 0 1 1 1 1 Ring finger domain PA PF02225.22 KXH48250.1 - 3.5e-10 39.8 0.0 9.1e-10 38.4 0.0 1.7 1 0 0 1 1 1 1 PA domain zf-C3HC4_2 PF13923.6 KXH48250.1 - 2.4e-09 36.9 3.9 3.7e-09 36.3 3.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KXH48250.1 - 6.8e-09 35.9 2.1 1.3e-08 34.9 2.1 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KXH48250.1 - 1.3e-08 34.6 3.1 2e-08 33.9 3.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KXH48250.1 - 3.3e-08 33.1 2.2 3.3e-08 33.1 2.2 1.8 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_5 PF14634.6 KXH48250.1 - 6.1e-07 29.3 2.4 9.4e-07 28.7 2.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KXH48250.1 - 5.5e-06 26.3 1.8 5.5e-05 23.1 2.5 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KXH48250.1 - 9.5e-06 25.4 2.9 1.4e-05 24.8 2.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KXH48250.1 - 0.0014 18.6 1.0 0.0025 17.8 1.0 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 KXH48250.1 - 0.0064 16.3 2.6 0.011 15.6 2.6 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KXH48250.1 - 0.048 13.8 3.5 0.16 12.1 3.6 1.9 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING Zn_ribbon_17 PF17120.5 KXH48250.1 - 0.065 12.9 3.0 0.12 12.0 3.0 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 KXH48250.1 - 0.1 12.8 2.4 0.25 11.5 2.4 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.7 KXH48250.1 - 0.21 11.7 2.6 0.43 10.7 2.6 1.6 1 1 0 1 1 1 0 RING-variant domain PHD PF00628.29 KXH48250.1 - 1.1 9.2 2.4 1.9 8.4 2.4 1.4 1 0 0 1 1 1 0 PHD-finger zf-RING-like PF08746.11 KXH48250.1 - 1.3 9.4 3.2 2.2 8.7 3.2 1.4 1 0 0 1 1 1 0 RING-like domain DUF4083 PF13314.6 KXH48250.1 - 6.1 6.9 5.6 17 5.5 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) Spc7 PF08317.11 KXH48252.1 - 0.00065 18.7 19.8 0.0014 17.6 2.6 2.5 3 0 0 3 3 3 2 Spc7 kinetochore protein BLOC1_2 PF10046.9 KXH48252.1 - 0.0037 17.5 4.7 0.0037 17.5 4.7 3.5 4 1 0 4 4 4 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Csm2_III-A PF03750.13 KXH48252.1 - 0.0047 17.7 4.1 0.0055 17.5 2.4 2.0 1 1 1 2 2 1 1 Csm2 Type III-A CorA PF01544.18 KXH48252.1 - 0.0071 15.7 3.6 0.011 15.1 3.6 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein OmpH PF03938.14 KXH48252.1 - 0.025 14.9 29.6 0.3 11.4 5.4 3.0 1 1 2 3 3 3 0 Outer membrane protein (OmpH-like) NPV_P10 PF05531.12 KXH48252.1 - 0.048 14.1 5.0 0.16 12.4 0.2 2.7 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF4407 PF14362.6 KXH48252.1 - 0.049 13.0 17.4 0.15 11.4 16.8 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) GAS PF13851.6 KXH48252.1 - 0.11 11.8 28.8 0.32 10.3 7.9 3.3 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding PAXX PF15384.6 KXH48252.1 - 0.15 11.7 12.3 0.28 10.9 0.7 3.0 1 1 2 3 3 3 0 PAXX, PAralog of XRCC4 and XLF, also called C9orf142 AAA_13 PF13166.6 KXH48252.1 - 0.16 10.6 14.1 0.24 10.0 14.1 1.4 1 1 0 1 1 1 0 AAA domain Fez1 PF06818.15 KXH48252.1 - 0.25 11.8 25.1 0.032 14.7 19.6 2.1 2 1 0 2 2 2 0 Fez1 LMBR1 PF04791.16 KXH48252.1 - 0.75 8.6 5.3 0.82 8.5 5.3 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Laminin_II PF06009.12 KXH48252.1 - 0.87 9.6 16.5 0.22 11.5 1.9 3.1 3 0 0 3 3 3 0 Laminin Domain II YlqD PF11068.8 KXH48252.1 - 1 9.7 19.5 0.85 10.0 5.0 3.0 3 0 0 3 3 3 0 YlqD protein FAM76 PF16046.5 KXH48252.1 - 1.1 8.5 14.1 0.59 9.4 4.7 2.1 2 0 0 2 2 2 0 FAM76 protein DUF1664 PF07889.12 KXH48252.1 - 1.2 9.1 6.6 9.6 6.3 0.4 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) Spc24 PF08286.11 KXH48252.1 - 1.4 9.2 20.1 0.063 13.5 3.0 3.6 3 1 0 3 3 3 0 Spc24 subunit of Ndc80 MPS2 PF17060.5 KXH48252.1 - 2 7.6 13.7 0.84 8.8 10.3 1.9 1 1 0 2 2 2 0 Monopolar spindle protein 2 IFT20 PF14931.6 KXH48252.1 - 2 8.6 16.0 0.26 11.5 6.8 2.9 2 1 1 3 3 3 0 Intraflagellar transport complex B, subunit 20 Cob_adeno_trans PF01923.18 KXH48252.1 - 2.3 8.3 13.8 0.099 12.8 0.8 2.8 2 1 1 3 3 3 0 Cobalamin adenosyltransferase Allexi_40kDa PF05549.11 KXH48252.1 - 2.4 7.6 5.9 0.87 9.0 1.9 2.0 2 0 0 2 2 2 0 Allexivirus 40kDa protein Cnn_1N PF07989.11 KXH48252.1 - 2.7 8.2 19.9 0.51 10.5 0.8 3.5 3 1 0 3 3 3 0 Centrosomin N-terminal motif 1 PEARLI-4 PF05278.12 KXH48252.1 - 3.8 7.0 14.9 0.7 9.4 4.4 2.3 2 0 0 2 2 2 0 Arabidopsis phospholipase-like protein (PEARLI 4) DUF948 PF06103.11 KXH48252.1 - 4.1 7.7 6.1 2.3 8.6 2.0 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) FapA PF03961.13 KXH48252.1 - 4.9 5.6 12.3 0.5 8.9 5.9 2.0 1 1 2 3 3 3 0 Flagellar Assembly Protein A PRKG1_interact PF15898.5 KXH48252.1 - 8.9 7.3 28.3 3.5 8.6 9.3 3.0 3 0 0 3 3 3 0 cGMP-dependent protein kinase interacting domain Ribosomal_L37e PF01907.19 KXH48253.1 - 5.1e-14 52.2 2.2 8.7e-14 51.4 2.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L37e ELP6 PF09807.9 KXH48254.1 - 6.4e-11 42.2 0.0 1.1e-10 41.4 0.0 1.4 1 1 0 1 1 1 1 Elongation complex protein 6 ATPase PF06745.13 KXH48254.1 - 0.0052 16.2 0.0 0.0075 15.6 0.0 1.2 1 0 0 1 1 1 1 KaiC MFS_1 PF07690.16 KXH48266.1 - 5.8e-40 137.3 20.0 5.8e-40 137.3 20.0 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1772 PF08592.11 KXH48266.1 - 1.4 9.2 6.1 12 6.2 0.1 3.0 2 2 1 3 3 3 0 Domain of unknown function (DUF1772) Pec_lyase_C PF00544.19 KXH48267.1 - 3.8e-15 56.0 8.8 1.2e-13 51.1 8.8 2.2 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 KXH48267.1 - 1.1e-05 25.3 17.6 0.00022 21.1 10.7 2.3 1 1 1 2 2 2 2 Right handed beta helix region Phage_attach PF05354.11 KXH48267.1 - 0.045 13.6 0.1 0.13 12.1 0.1 1.8 1 0 0 1 1 1 0 Phage Head-Tail Attachment Calc_CGRP_IAPP PF00214.19 KXH48268.1 - 0.004 17.5 0.1 0.0047 17.3 0.1 1.1 1 0 0 1 1 1 1 Calcitonin / CGRP / IAPP family DUF4381 PF14316.6 KXH48268.1 - 0.012 15.8 1.6 0.025 14.8 1.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4381) UPF0239 PF06783.11 KXH48268.1 - 0.072 13.3 0.1 0.1 12.8 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0239) HA2 PF04408.23 KXH48268.1 - 0.12 12.7 1.3 0.17 12.2 1.3 1.3 1 1 0 1 1 1 0 Helicase associated domain (HA2) Connexin PF00029.19 KXH48268.1 - 0.12 12.1 0.1 0.14 11.9 0.1 1.1 1 0 0 1 1 1 0 Connexin PUCC PF03209.15 KXH48268.1 - 0.21 10.5 0.1 0.31 10.0 0.1 1.3 1 1 0 1 1 1 0 PUCC protein GvpL_GvpF PF06386.11 KXH48268.1 - 0.48 10.3 7.0 0.53 10.2 7.0 1.0 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF HATPase_c_3 PF13589.6 KXH48269.1 - 5.8e-15 55.3 0.0 1e-14 54.5 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.11 KXH48269.1 - 4.5e-11 42.7 0.0 8.8e-10 38.5 0.0 2.4 2 0 0 2 2 2 1 MutL C terminal dimerisation domain His_Phos_1 PF00300.22 KXH48269.1 - 0.0008 19.1 0.1 0.0024 17.6 0.1 1.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) HATPase_c PF02518.26 KXH48269.1 - 0.069 13.7 0.0 0.17 12.4 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CN_hydrolase PF00795.22 KXH48271.1 - 1.5e-31 109.7 0.0 9.6e-31 107.1 0.0 2.0 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase DUF3784 PF12650.7 KXH48272.1 - 0.018 15.2 1.7 0.036 14.3 1.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3784) DUF2207 PF09972.9 KXH48272.1 - 0.063 12.0 0.1 0.078 11.7 0.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) SdpI PF13630.6 KXH48272.1 - 2.2 8.4 5.7 4.6 7.4 5.7 1.5 1 0 0 1 1 1 0 SdpI/YhfL protein family DAO PF01266.24 KXH48273.1 - 1.7e-32 113.4 9.7 3.1e-32 112.5 9.7 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXH48273.1 - 0.034 14.4 1.1 0.24 11.6 0.7 2.6 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain IPK PF03770.16 KXH48274.1 - 1.2e-56 191.7 0.0 4.7e-56 189.8 0.0 1.9 2 0 0 2 2 2 1 Inositol polyphosphate kinase TraE PF05309.11 KXH48275.1 - 4 6.8 5.3 1.1 8.6 0.0 2.4 3 0 0 3 3 3 0 TraE protein SBP_bac_11 PF13531.6 KXH48297.1 - 3.4e-06 27.0 0.0 4.9e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 KXH48297.1 - 9.7e-06 25.7 2.1 1.9e-05 24.8 2.1 1.5 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_6 PF13343.6 KXH48297.1 - 1.9e-05 24.2 0.2 3.1e-05 23.5 0.2 1.3 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein Sugar_tr PF00083.24 KXH48298.1 - 1.3e-128 429.8 23.5 1.5e-128 429.5 23.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH48298.1 - 4e-25 88.5 40.6 1.2e-19 70.5 15.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily YqfD PF06898.11 KXH48298.1 - 0.12 11.2 1.7 1.6 7.4 0.0 2.3 2 0 0 2 2 2 0 Putative stage IV sporulation protein YqfD Glyoxalase PF00903.25 KXH48299.1 - 4.4e-12 46.3 0.0 1.1e-11 45.1 0.0 1.6 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KXH48299.1 - 1.1e-08 35.3 0.0 1.4e-08 35.0 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 KXH48299.1 - 9.6e-07 29.6 0.0 1.8e-06 28.7 0.0 1.4 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_3 PF13468.6 KXH48299.1 - 0.014 15.6 0.0 1.1 9.4 0.0 2.1 2 0 0 2 2 2 0 Glyoxalase-like domain Glyco_hydro_3_C PF01915.22 KXH48300.1 - 4.5e-45 154.1 0.0 7.3e-45 153.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KXH48300.1 - 9.5e-35 120.5 0.0 1.8e-34 119.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KXH48300.1 - 2e-21 75.9 0.0 3.6e-21 75.1 0.0 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain GCR1_C PF12550.8 KXH48301.1 - 2.6e-18 66.1 0.3 7.3e-18 64.7 0.1 1.9 2 0 0 2 2 2 1 Transcriptional activator of glycolytic enzymes F-box-like PF12937.7 KXH48302.1 - 2.1e-09 37.1 0.8 7.5e-09 35.3 0.2 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KXH48302.1 - 0.17 11.8 1.1 3.8 7.5 1.1 2.9 1 1 0 1 1 1 0 F-box domain Tme5_EGF_like PF09064.10 KXH48305.1 - 0.13 12.2 4.2 0.29 11.1 4.2 1.6 1 0 0 1 1 1 0 Thrombomodulin like fifth domain, EGF-like Cyto_heme_lyase PF01265.17 KXH48308.1 - 2.7e-115 385.0 4.1 8.5e-114 380.1 4.1 2.0 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase CbtB PF09489.10 KXH48308.1 - 2 8.6 5.8 12 6.1 0.6 2.5 2 0 0 2 2 2 0 Probable cobalt transporter subunit (CbtB) ABC1 PF03109.16 KXH48309.1 - 5.6e-23 81.4 0.1 1.3e-13 51.1 0.0 2.9 3 0 0 3 3 3 2 ABC1 family APH PF01636.23 KXH48309.1 - 0.0057 16.6 1.5 0.052 13.5 0.1 2.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 KXH48309.1 - 0.054 13.1 0.0 0.3 10.6 0.0 2.0 2 0 0 2 2 2 0 RIO1 family ATG16 PF08614.11 KXH48310.1 - 0.00049 20.4 64.1 0.0085 16.3 30.6 4.5 3 1 2 5 5 5 3 Autophagy protein 16 (ATG16) APG6_N PF17675.1 KXH48310.1 - 0.023 15.2 16.7 0.023 15.2 16.7 5.2 1 1 4 5 5 5 0 Apg6 coiled-coil region DUF2935 PF11155.8 KXH48310.1 - 0.041 14.2 4.4 8.2 6.8 4.4 3.2 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) TSC22 PF01166.18 KXH48310.1 - 0.081 13.2 10.7 0.86 10.0 0.6 4.6 2 1 2 4 4 4 0 TSC-22/dip/bun family Macoilin PF09726.9 KXH48310.1 - 0.95 7.9 45.4 0.023 13.3 25.4 2.3 2 0 0 2 2 2 0 Macoilin family NdhM PF10664.9 KXH48310.1 - 6.7 7.0 6.3 2 8.7 0.1 3.0 3 2 1 4 4 4 0 Cyanobacterial and plastid NDH-1 subunit M Protoglobin PF11563.8 KXH48311.1 - 4.7e-58 195.6 0.1 5.7e-58 195.3 0.1 1.1 1 0 0 1 1 1 1 Protoglobin Cys_Met_Meta_PP PF01053.20 KXH48313.1 - 1e-141 471.9 0.0 1.4e-141 471.4 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KXH48313.1 - 6.4e-08 32.1 0.1 1.2e-07 31.3 0.1 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KXH48313.1 - 9.9e-08 31.3 0.1 1.7e-07 30.6 0.1 1.3 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KXH48313.1 - 4.7e-07 29.4 0.1 1e-06 28.3 0.1 1.5 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Zn_clus PF00172.18 KXH48313.1 - 7.1e-07 29.2 8.6 1.3e-06 28.4 8.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SepSecS PF05889.13 KXH48313.1 - 0.00024 20.0 0.2 0.004 15.9 0.1 2.1 2 0 0 2 2 2 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Beta_elim_lyase PF01212.21 KXH48313.1 - 0.0014 18.0 0.0 0.0031 16.8 0.0 1.6 1 0 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.11 KXH48313.1 - 0.027 13.0 0.0 0.042 12.4 0.0 1.2 1 0 0 1 1 1 0 Methionine gamma-lyase GDC-P PF02347.16 KXH48313.1 - 0.027 13.3 0.0 0.053 12.4 0.0 1.4 1 0 0 1 1 1 0 Glycine cleavage system P-protein Fungal_trans PF04082.18 KXH48313.1 - 0.079 12.0 0.0 0.16 10.9 0.0 1.6 1 0 0 1 1 1 0 Fungal specific transcription factor domain BRK PF07533.16 KXH48313.1 - 0.14 11.8 1.2 1 9.0 0.4 2.3 2 0 0 2 2 2 0 BRK domain CN_hydrolase PF00795.22 KXH48314.1 - 8.7e-55 185.9 0.0 1.7e-54 184.9 0.0 1.4 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase Abhydrolase_1 PF00561.20 KXH48315.1 - 5.5e-43 147.5 0.0 6.6e-43 147.2 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXH48315.1 - 6.7e-05 23.6 0.4 0.00012 22.8 0.4 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family AA_kinase PF00696.28 KXH48316.1 - 2.7e-35 122.1 0.0 6.1e-35 121.0 0.0 1.6 2 0 0 2 2 2 1 Amino acid kinase family ACT_7 PF13840.6 KXH48316.1 - 2.2e-12 46.6 4.6 7.4e-11 41.7 3.6 2.4 2 0 0 2 2 2 1 ACT domain ACT PF01842.25 KXH48316.1 - 1.8e-05 24.4 0.8 6.5e-05 22.6 0.3 2.1 2 0 0 2 2 2 1 ACT domain SecD-TM1 PF13721.6 KXH48316.1 - 0.14 12.7 0.3 3.7 8.1 0.0 2.5 2 0 0 2 2 2 0 SecD export protein N-terminal TM region DUF4898 PF16239.5 KXH48316.1 - 0.16 11.9 0.0 0.41 10.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4898) GH131_N PF18271.1 KXH48317.1 - 1.9e-82 276.8 1.1 2.2e-82 276.6 1.1 1.0 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain Pept_tRNA_hydro PF01195.19 KXH48318.1 - 0.19 11.7 0.0 0.36 10.8 0.0 1.3 1 0 0 1 1 1 0 Peptidyl-tRNA hydrolase F-box PF00646.33 KXH48384.1 - 2.6e-07 30.3 0.3 2.6e-07 30.3 0.3 2.4 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KXH48384.1 - 1e-06 28.5 1.2 3.3e-06 26.9 0.1 2.3 2 0 0 2 2 2 1 F-box-like RPEL PF02755.15 KXH48384.1 - 1.9e-05 24.2 0.1 0.00031 20.3 0.1 2.5 2 0 0 2 2 2 1 RPEL repeat F-box_4 PF15966.5 KXH48384.1 - 0.0034 17.3 1.0 0.017 15.0 0.0 2.2 2 0 0 2 2 2 1 F-box PRANC PF09372.10 KXH48384.1 - 0.24 11.8 0.0 0.38 11.1 0.0 1.3 1 0 0 1 1 1 0 PRANC domain DUF747 PF05346.11 KXH48385.1 - 3.4e-120 401.3 5.5 4.2e-120 401.0 5.5 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family OSTbeta PF15048.6 KXH48385.1 - 0.17 12.1 0.0 0.54 10.4 0.0 1.9 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein DUF1761 PF08570.10 KXH48385.1 - 0.21 11.9 6.7 0.15 12.3 0.3 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1761) DUF5524 PF17662.1 KXH48385.1 - 0.63 9.3 11.1 0.4 10.0 9.0 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5524) CDC45 PF02724.14 KXH48385.1 - 5 5.3 7.0 8.5 4.5 7.0 1.2 1 0 0 1 1 1 0 CDC45-like protein DLH PF01738.18 KXH48386.1 - 1.1e-25 90.5 0.4 1.4e-25 90.1 0.4 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family GMC_oxred_N PF00732.19 KXH48387.1 - 4e-55 187.3 0.0 1.2e-54 185.7 0.0 1.7 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXH48387.1 - 2.7e-35 122.0 0.1 4.7e-35 121.2 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 KXH48387.1 - 0.0073 15.9 1.2 0.093 12.3 0.2 2.8 3 1 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KXH48387.1 - 0.034 13.2 0.2 0.27 10.2 0.1 2.0 2 0 0 2 2 2 0 FAD binding domain Lycopene_cycl PF05834.12 KXH48387.1 - 0.035 13.1 0.0 0.052 12.6 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_8 PF13450.6 KXH48387.1 - 0.16 12.2 0.1 0.44 10.8 0.1 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain SLATT_5 PF18160.1 KXH48388.1 - 0.022 14.1 0.4 0.055 12.8 0.4 1.6 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 P53_tetramer PF07710.11 KXH48388.1 - 0.055 12.8 0.0 0.17 11.3 0.0 1.9 1 0 0 1 1 1 0 P53 tetramerisation motif WD40 PF00400.32 KXH48389.1 - 6.2e-40 134.4 23.0 1.4e-05 25.8 0.0 8.2 8 0 0 8 8 8 7 WD domain, G-beta repeat F-box PF00646.33 KXH48389.1 - 1.7e-10 40.5 1.0 4.2e-10 39.2 0.2 2.1 2 1 0 2 2 2 1 F-box domain F-box-like PF12937.7 KXH48389.1 - 2.5e-10 40.1 0.1 5e-10 39.1 0.1 1.6 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 KXH48389.1 - 4.5e-08 33.3 1.2 2.1 8.7 0.0 5.7 2 2 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 KXH48389.1 - 0.0024 17.5 0.6 0.47 10.0 0.0 2.8 2 1 1 3 3 3 1 PQQ-like domain F-box_4 PF15966.5 KXH48389.1 - 0.011 15.7 0.0 0.029 14.3 0.0 1.7 1 0 0 1 1 1 0 F-box Nup160 PF11715.8 KXH48389.1 - 0.095 11.3 4.8 39 2.7 0.0 4.6 3 1 2 5 5 5 0 Nucleoporin Nup120/160 DUF4597 PF15366.6 KXH48389.1 - 0.5 10.1 6.2 0.71 9.7 0.1 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4597) TraQ PF09679.10 KXH48391.1 - 0.074 13.0 0.1 0.19 11.7 0.1 1.6 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin chaperone (TraQ) TPR_4 PF07721.14 KXH48391.1 - 0.17 12.6 1.4 0.62 10.9 1.4 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat Zn_clus PF00172.18 KXH48392.1 - 0.00059 19.9 12.2 0.00059 19.9 12.2 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_jaz PF12171.8 KXH48392.1 - 0.0095 16.2 0.1 0.02 15.2 0.1 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-MYST PF17772.1 KXH48392.1 - 0.0099 15.5 0.4 0.045 13.4 0.1 2.3 2 0 0 2 2 2 1 MYST family zinc finger domain zf-C2H2 PF00096.26 KXH48392.1 - 0.033 14.7 0.3 0.033 14.7 0.3 2.8 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-met PF12874.7 KXH48392.1 - 0.05 14.0 0.2 0.11 12.9 0.2 1.7 1 0 0 1 1 1 0 Zinc-finger of C2H2 type adh_short PF00106.25 KXH48394.1 - 8.5e-37 126.5 0.0 1.7e-36 125.5 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXH48394.1 - 2.6e-27 95.9 0.0 4e-27 95.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH48394.1 - 5.8e-14 52.4 0.0 7.8e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KXH48394.1 - 1.4e-06 28.3 0.0 2.9e-06 27.3 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KXH48394.1 - 2.8e-06 27.0 0.0 4.3e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXH48394.1 - 2.9e-05 23.6 0.3 0.00032 20.2 0.3 1.9 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KXH48394.1 - 7.3e-05 21.9 0.0 0.00012 21.2 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Sacchrp_dh_NADP PF03435.18 KXH48394.1 - 0.00015 22.0 0.0 0.00026 21.3 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NmrA PF05368.13 KXH48394.1 - 0.0068 16.0 0.1 0.01 15.4 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.15 KXH48394.1 - 0.04 13.0 0.1 0.12 11.5 0.1 1.7 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein Shikimate_DH PF01488.20 KXH48394.1 - 0.087 12.9 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase p450 PF00067.22 KXH48396.1 - 2.6e-48 164.9 0.0 3.5e-48 164.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_M43 PF05572.13 KXH48397.1 - 2.6e-15 56.6 0.5 4.2e-15 56.0 0.5 1.4 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.6 KXH48397.1 - 2.7e-06 27.9 0.0 4.6e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 KXH48397.1 - 4.2e-06 27.1 0.0 6.9e-06 26.3 0.0 1.3 1 1 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M10 PF00413.24 KXH48397.1 - 0.00033 20.5 0.0 0.00069 19.5 0.0 1.5 1 1 0 1 1 1 1 Matrixin Reprolysin_4 PF13583.6 KXH48397.1 - 0.018 14.7 1.2 0.032 13.9 1.2 1.5 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like DUF4953 PF16313.5 KXH48397.1 - 0.046 12.9 1.2 0.07 12.3 0.2 1.7 2 0 0 2 2 2 0 Met-zincin Reprolysin_2 PF13574.6 KXH48397.1 - 0.056 13.3 0.1 0.075 12.9 0.1 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.9 KXH48397.1 - 0.11 11.5 1.0 0.19 10.6 1.0 1.4 1 0 0 1 1 1 0 Peptidase M66 Ecl1 PF12855.7 KXH48404.1 - 3.1e-15 57.8 22.5 4e-15 57.4 22.5 1.2 1 0 0 1 1 1 1 ECL1/2/3 zinc binding proteins HipA_C PF07804.12 KXH48404.1 - 0.065 12.9 0.1 0.077 12.7 0.1 1.2 1 0 0 1 1 1 0 HipA-like C-terminal domain zf-MYND PF01753.18 KXH48404.1 - 0.078 13.1 1.8 0.14 12.2 1.8 1.4 1 0 0 1 1 1 0 MYND finger Astacin PF01400.24 KXH48405.1 - 2.4e-34 118.7 0.0 2.3e-33 115.4 0.0 2.1 1 1 0 1 1 1 1 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.24 KXH48405.1 - 0.021 14.6 0.0 0.31 10.9 0.0 2.4 2 0 0 2 2 2 0 Matrixin His_Phos_1 PF00300.22 KXH48406.1 - 3.5e-26 92.1 0.0 7.2e-26 91.1 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF1168 PF06658.12 KXH48407.1 - 2.4e-35 121.3 23.7 1.9e-34 118.4 23.7 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1168) Lyase_catalyt PF09093.11 KXH48407.1 - 0.042 13.0 0.0 0.058 12.5 0.0 1.1 1 0 0 1 1 1 0 Lyase, catalytic PPL5 PF18168.1 KXH48407.1 - 4 6.6 6.6 0.82 8.9 2.2 1.8 2 0 0 2 2 2 0 Prim-pol family 5 XRN_M PF17846.1 KXH48407.1 - 4.5 6.1 6.4 5.9 5.7 6.4 1.1 1 0 0 1 1 1 0 Xrn1 helical domain DNA_pol3_a_NII PF11490.8 KXH48407.1 - 9 6.2 9.0 16 5.4 9.0 1.3 1 0 0 1 1 1 0 DNA polymerase III polC-type N-terminus II Presenilin PF01080.17 KXH48407.1 - 9.2 4.9 9.5 12 4.5 9.5 1.1 1 0 0 1 1 1 0 Presenilin Cpn60_TCP1 PF00118.24 KXH48408.1 - 7.1e-172 572.4 0.1 8.1e-172 572.2 0.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family HATPase_c PF02518.26 KXH48410.1 - 3.9e-26 91.8 0.4 7.3e-26 90.9 0.4 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KXH48410.1 - 3.7e-23 81.8 0.1 2.7e-22 79.0 0.0 2.4 2 0 0 2 2 2 1 Response regulator receiver domain PAS_3 PF08447.12 KXH48410.1 - 8.4e-23 80.5 1.1 7.6e-13 48.6 0.4 3.9 3 0 0 3 3 3 3 PAS fold HisKA PF00512.25 KXH48410.1 - 9.4e-20 70.4 0.5 3.7e-19 68.5 0.1 2.3 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS PF00989.25 KXH48410.1 - 1.6e-09 37.7 0.0 0.0024 17.9 0.0 2.9 3 0 0 3 3 3 2 PAS fold PAS_4 PF08448.10 KXH48410.1 - 1.9e-09 37.8 0.2 7.6e-06 26.1 0.1 3.1 3 0 0 3 3 3 2 PAS fold PAS_9 PF13426.7 KXH48410.1 - 4.3e-09 36.6 0.0 0.0021 18.3 0.0 3.6 2 1 0 2 2 2 2 PAS domain PAS_8 PF13188.7 KXH48410.1 - 0.01 15.8 0.0 0.76 9.9 0.0 2.5 2 0 0 2 2 2 0 PAS domain Ssl1 PF04056.14 KXH48411.1 - 7.3e-74 247.8 0.0 9.7e-74 247.4 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like VWA_2 PF13519.6 KXH48411.1 - 3.1e-15 56.7 0.0 6.2e-15 55.8 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 KXH48411.1 - 0.00074 19.8 0.0 0.0014 18.9 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain Tfb4 PF03850.14 KXH48411.1 - 0.36 10.3 3.9 0.6 9.6 3.9 1.3 1 0 0 1 1 1 0 Transcription factor Tfb4 DZR PF12773.7 KXH48411.1 - 7.1 6.7 9.9 14 5.8 6.3 2.4 2 0 0 2 2 2 0 Double zinc ribbon Glyoxalase PF00903.25 KXH48412.1 - 1.9e-23 83.0 0.1 3.5e-15 56.3 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KXH48412.1 - 1.5e-11 44.5 0.1 7.3e-05 23.0 0.1 2.4 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 KXH48412.1 - 5.4e-05 23.4 0.1 0.38 10.9 0.0 3.0 2 1 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_5 PF14696.6 KXH48412.1 - 0.0013 18.9 0.0 0.0071 16.5 0.0 2.0 2 0 0 2 2 2 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal TPR_17 PF13431.6 KXH48413.1 - 0.091 13.2 0.2 0.76 10.3 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Ribosomal_L27e PF01777.18 KXH48414.1 - 4.8e-37 126.2 5.0 4.8e-37 126.2 5.0 1.5 2 0 0 2 2 2 1 Ribosomal L27e protein family TPT PF03151.16 KXH48415.1 - 7e-26 91.2 26.9 8.6e-26 90.9 26.9 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KXH48415.1 - 0.00045 20.4 40.6 0.0097 16.1 13.0 2.4 3 0 0 3 3 3 2 EamA-like transporter family Amino_oxidase PF01593.24 KXH48416.1 - 1.4e-08 34.5 0.0 2.5e-08 33.7 0.0 1.5 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KXH48416.1 - 1.2e-07 31.9 0.1 2.9e-07 30.6 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXH48416.1 - 0.00071 18.9 0.0 0.01 15.1 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KXH48416.1 - 0.013 14.8 0.1 0.02 14.2 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 KXH48416.1 - 0.044 13.0 0.1 0.082 12.1 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXH48416.1 - 0.046 12.4 0.1 0.071 11.8 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Lycopene_cycl PF05834.12 KXH48416.1 - 0.047 12.7 1.0 0.094 11.7 0.2 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein Thi4 PF01946.17 KXH48416.1 - 0.049 12.9 0.7 0.091 12.0 0.1 1.7 2 0 0 2 2 2 0 Thi4 family FAD_binding_2 PF00890.24 KXH48416.1 - 0.1 11.7 0.2 0.15 11.1 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.24 KXH48416.1 - 0.13 11.8 0.2 0.22 11.1 0.2 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KXH48416.1 - 0.14 11.5 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.22 KXH48416.1 - 0.22 10.6 0.5 2.9 6.9 0.1 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A Glyco_hydro_43 PF04616.14 KXH48517.1 - 6.5e-46 156.9 1.8 9.4e-46 156.4 1.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 KXH48517.1 - 5.7e-14 52.3 0.0 8.6e-14 51.7 0.0 1.2 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain p450 PF00067.22 KXH48518.1 - 6.4e-62 209.8 0.0 8.3e-62 209.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 BatA PF07584.11 KXH48518.1 - 0.069 13.5 1.0 0.18 12.2 0.6 1.9 2 0 0 2 2 2 0 Aerotolerance regulator N-terminal p450 PF00067.22 KXH48520.1 - 3.2e-59 200.9 0.0 4.2e-59 200.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 COX7B PF05392.11 KXH48520.1 - 0.099 12.3 0.1 0.78 9.5 0.0 2.3 2 0 0 2 2 2 0 Cytochrome C oxidase chain VIIB Propeptide_C1 PF08127.13 KXH48521.1 - 0.047 13.6 0.0 0.097 12.6 0.0 1.5 1 0 0 1 1 1 0 Peptidase family C1 propeptide peroxidase PF00141.23 KXH48522.1 - 7.6e-24 84.7 0.0 1.1e-23 84.1 0.0 1.2 1 0 0 1 1 1 1 Peroxidase Mannosyl_trans3 PF11051.8 KXH48523.1 - 4.4e-25 88.6 0.4 5.8e-16 58.7 0.0 2.1 1 1 1 2 2 2 2 Mannosyltransferase putative AMP-binding PF00501.28 KXH48524.1 - 1.6e-54 185.1 0.0 3.9e-28 98.2 0.0 2.1 1 1 1 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 KXH48524.1 - 7.7e-05 23.6 0.0 0.00015 22.7 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Aldolase_II PF00596.21 KXH48525.1 - 1.4e-31 109.9 0.4 1.9e-31 109.5 0.4 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain SUV3_C PF12513.8 KXH48525.1 - 0.032 14.1 0.0 0.085 12.8 0.0 1.7 1 0 0 1 1 1 0 Mitochondrial degradasome RNA helicase subunit C terminal AA_permease_2 PF13520.6 KXH48526.1 - 4.8e-55 187.1 52.8 6.5e-55 186.7 52.8 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXH48526.1 - 1.6e-22 79.7 47.6 2.2e-22 79.3 47.6 1.1 1 0 0 1 1 1 1 Amino acid permease CN_hydrolase PF00795.22 KXH48527.1 - 4.4e-34 118.0 0.0 5.7e-34 117.6 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Fungal_trans_2 PF11951.8 KXH48528.1 - 3.3e-24 85.4 3.7 1.2e-23 83.6 3.7 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain KRAB PF01352.27 KXH48528.1 - 0.04 13.6 0.7 0.11 12.2 0.7 1.7 1 0 0 1 1 1 0 KRAB box TFIID-18kDa PF02269.16 KXH48529.1 - 4e-26 90.8 2.1 1.1e-23 83.1 1.1 2.5 2 0 0 2 2 2 2 Transcription initiation factor IID, 18kD subunit TFIID_20kDa PF03847.13 KXH48529.1 - 0.15 12.6 3.4 2.5 8.7 0.3 2.6 3 0 0 3 3 3 0 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.23 KXH48529.1 - 0.69 10.2 4.9 8.9 6.7 0.3 3.4 5 0 0 5 5 5 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Abhydrolase_1 PF00561.20 KXH48530.1 - 2e-17 63.7 0.0 5.8e-17 62.2 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXH48530.1 - 1.7e-14 53.7 0.0 6.5e-14 51.8 0.0 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KXH48530.1 - 5.1e-13 50.2 0.0 9.6e-13 49.2 0.0 1.4 1 1 1 2 2 2 1 Alpha/beta hydrolase family Ndr PF03096.14 KXH48530.1 - 2e-06 26.8 0.0 2.7e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 Ndr family BAAT_C PF08840.11 KXH48530.1 - 0.00063 19.7 0.0 0.4 10.6 0.0 2.1 2 0 0 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal Asp-B-Hydro_N PF05279.11 KXH48531.1 - 3.7 7.5 11.5 7.7 6.5 0.6 2.3 2 0 0 2 2 2 0 Aspartyl beta-hydroxylase N-terminal region DUF1515 PF07439.11 KXH48534.1 - 0.044 13.8 0.4 0.052 13.6 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) MULE PF10551.9 KXH48535.1 - 0.0011 19.3 0.0 0.0034 17.8 0.0 1.8 1 0 0 1 1 1 1 MULE transposase domain Cys_rich_VLP PF14194.6 KXH48536.1 - 0.5 10.5 5.6 3.8 7.7 1.5 2.6 1 1 1 2 2 2 0 Cysteine-rich VLP Fungal_trans PF04082.18 KXH48539.1 - 8e-23 80.8 0.1 1.1e-22 80.3 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 KXH48557.1 - 1.1e-17 64.0 35.6 1.1e-17 64.0 35.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH48557.1 - 8.8e-07 28.1 5.5 8.8e-07 28.1 5.5 3.1 1 1 1 2 2 2 1 Sugar (and other) transporter DUF4131 PF13567.6 KXH48557.1 - 0.093 12.4 0.2 0.093 12.4 0.2 4.1 3 3 3 6 6 6 0 Domain of unknown function (DUF4131) Bromodomain PF00439.25 KXH48558.1 - 3.4e-16 59.1 0.0 7.4e-16 58.0 0.0 1.7 1 0 0 1 1 1 1 Bromodomain BTB PF00651.31 KXH48558.1 - 0.0015 18.7 0.0 0.006 16.8 0.0 2.0 2 0 0 2 2 2 1 BTB/POZ domain Hamartin PF04388.12 KXH48558.1 - 0.032 12.9 0.8 0.042 12.5 0.8 1.3 1 0 0 1 1 1 0 Hamartin protein Ribonuclease_T2 PF00445.18 KXH48559.1 - 3.9e-34 118.5 0.6 5.5e-34 118.0 0.6 1.1 1 0 0 1 1 1 1 Ribonuclease T2 family Cadherin_C PF01049.17 KXH48559.1 - 0.14 12.5 0.0 0.2 12.0 0.0 1.2 1 0 0 1 1 1 0 Cadherin cytoplasmic region Sec62 PF03839.16 KXH48560.1 - 8.4e-71 237.9 1.7 8.4e-71 237.9 1.7 2.0 2 0 0 2 2 2 1 Translocation protein Sec62 DUF4834 PF16118.5 KXH48560.1 - 0.54 11.2 9.5 35 5.5 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) Corona_M PF01635.18 KXH48560.1 - 1 8.6 6.6 1.6 8.0 6.6 1.2 1 0 0 1 1 1 0 Coronavirus M matrix/glycoprotein SelP_N PF04592.14 KXH48560.1 - 1.9 7.9 19.2 3.8 6.8 19.2 1.5 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Neur_chan_memb PF02932.16 KXH48560.1 - 3 7.8 5.2 6.3 6.8 5.2 1.7 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Zip PF02535.22 KXH48560.1 - 3.1 6.9 9.4 0.17 11.0 3.0 2.1 2 1 1 3 3 3 0 ZIP Zinc transporter PAT1 PF09770.9 KXH48560.1 - 3.3 5.9 18.6 4.3 5.5 18.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.13 KXH48560.1 - 4.6 7.1 21.8 0.13 12.3 15.5 1.6 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit E1-E2_ATPase PF00122.20 KXH48562.1 - 4.4e-49 166.5 6.1 4.4e-49 166.5 6.1 2.5 4 0 0 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 KXH48562.1 - 3.9e-28 99.2 2.6 4.2e-28 99.1 0.9 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 KXH48562.1 - 2.4e-11 43.9 0.0 1.1e-09 38.6 0.0 3.0 2 0 0 2 2 2 1 Heavy-metal-associated domain Phage_stabilise PF11134.8 KXH48562.1 - 0.081 11.8 0.3 0.14 11.0 0.3 1.2 1 0 0 1 1 1 0 Phage stabilisation protein Hydrolase_3 PF08282.12 KXH48562.1 - 0.18 11.5 1.8 13 5.5 0.2 2.4 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase OPT PF03169.15 KXH48563.1 - 6.3e-204 679.1 41.0 7.4e-204 678.9 41.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Acetyltransf_3 PF13302.7 KXH48564.1 - 4.7e-15 56.5 0.0 9e-15 55.6 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXH48564.1 - 2.3e-05 24.6 0.2 3.8e-05 23.9 0.2 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Fringe PF02434.16 KXH48565.1 - 0.015 14.8 0.0 0.022 14.2 0.0 1.3 1 0 0 1 1 1 0 Fringe-like TPR_1 PF00515.28 KXH48567.1 - 3e-07 30.0 12.4 0.013 15.3 0.5 3.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 KXH48567.1 - 9.1e-07 28.5 7.8 0.25 11.5 0.2 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KXH48567.1 - 0.0022 18.2 1.6 0.0065 16.7 1.6 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 KXH48567.1 - 0.0075 16.4 4.0 8.3 6.9 0.4 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 KXH48567.1 - 0.078 13.4 0.6 2 9.0 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3343 PF11823.8 KXH48567.1 - 0.085 12.3 0.3 0.65 9.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3343) Pox_T4_N PF04491.12 KXH48567.1 - 0.16 11.8 0.1 2.4 8.1 0.0 2.6 2 0 0 2 2 2 0 Poxvirus T4 protein, N terminus MFS_1 PF07690.16 KXH48568.1 - 6.4e-37 127.3 22.9 8.7e-29 100.5 2.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH48568.1 - 4.7e-08 32.3 7.8 4.7e-08 32.3 7.8 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KXH48568.1 - 0.011 14.2 1.0 0.018 13.5 1.0 1.3 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.7 KXH48568.1 - 0.023 13.6 13.2 0.14 11.0 4.3 2.7 3 0 0 3 3 3 0 MFS_1 like family BT1 PF03092.16 KXH48568.1 - 0.18 10.0 6.0 2 6.5 0.1 2.2 2 0 0 2 2 2 0 BT1 family NACHT_N PF17100.5 KXH48569.1 - 7.6e-60 202.5 0.2 1.6e-59 201.5 0.2 1.5 1 0 0 1 1 1 1 N-terminal domain of NWD NACHT-NTPase MFS_1 PF07690.16 KXH48569.1 - 2.6e-36 125.3 47.7 8.5e-34 117.0 23.0 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily WD40 PF00400.32 KXH48569.1 - 3e-28 97.5 27.1 1.2e-06 29.1 0.1 10.5 11 0 0 11 11 11 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXH48569.1 - 1.8e-17 63.4 3.7 0.019 15.3 0.1 8.7 3 1 6 9 9 9 4 Anaphase-promoting complex subunit 4 WD40 domain NACHT PF05729.12 KXH48569.1 - 3.1e-16 59.7 0.0 7.6e-16 58.5 0.0 1.6 1 0 0 1 1 1 1 NACHT domain TRI12 PF06609.13 KXH48569.1 - 0.00014 20.5 5.7 0.00026 19.6 5.7 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Ge1_WD40 PF16529.5 KXH48569.1 - 0.00028 19.9 1.8 1.2 8.0 0.0 4.5 4 1 0 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_2 PF13360.6 KXH48569.1 - 0.0023 17.6 0.1 0.21 11.1 0.0 2.7 1 1 0 2 2 2 1 PQQ-like domain PD40 PF07676.12 KXH48569.1 - 0.011 15.7 7.0 8.9 6.4 0.0 5.2 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat PALB2_WD40 PF16756.5 KXH48569.1 - 0.02 13.8 0.1 0.2 10.5 0.0 2.7 3 1 1 4 4 4 0 Partner and localizer of BRCA2 WD40 domain Lactamase_B_2 PF12706.7 KXH48570.1 - 1e-15 57.8 0.3 1.8e-15 57.0 0.3 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KXH48570.1 - 9.9e-12 45.0 0.0 1.4e-11 44.6 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Isochorismatase PF00857.20 KXH48571.1 - 3.8e-33 115.1 0.0 1.2e-31 110.2 0.0 2.0 1 1 0 1 1 1 1 Isochorismatase family Zn_clus PF00172.18 KXH48572.1 - 6.2e-06 26.2 11.0 1.1e-05 25.4 11.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Inositol_P PF00459.25 KXH48573.1 - 2e-68 230.9 0.0 2.3e-68 230.6 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family ArfA PF03889.13 KXH48573.1 - 0.17 11.4 0.1 0.32 10.5 0.1 1.4 1 0 0 1 1 1 0 Alternative ribosome-rescue factor A RCR PF12273.8 KXH48574.1 - 0.003 18.2 0.1 0.003 18.2 0.1 2.7 1 1 2 3 3 3 1 Chitin synthesis regulation, resistance to Congo red His_Phos_2 PF00328.22 KXH48575.1 - 3.4e-69 234.0 0.0 4.1e-69 233.8 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Dynamin_N PF00350.23 KXH48576.1 - 4.9e-30 104.8 0.6 1e-17 64.7 0.0 3.0 2 1 1 3 3 3 2 Dynamin family Dynamin_M PF01031.20 KXH48576.1 - 6.8e-26 91.1 0.0 9.1e-23 80.9 0.0 2.2 2 0 0 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.23 KXH48576.1 - 5.6e-05 23.2 0.0 0.00026 21.1 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KXH48576.1 - 0.015 15.7 0.8 0.1 12.9 0.0 2.6 2 1 1 3 3 3 0 AAA ATPase domain FeoB_N PF02421.18 KXH48576.1 - 0.024 14.2 0.0 8.3 5.9 0.0 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_15 PF13175.6 KXH48576.1 - 0.025 14.3 0.1 0.99 9.0 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain GTP_EFTU PF00009.27 KXH48576.1 - 0.054 13.0 0.2 2.6 7.5 0.0 2.8 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain RRN3 PF05327.11 KXH48576.1 - 0.055 12.0 1.3 0.089 11.3 1.3 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 PPP4R2 PF09184.11 KXH48576.1 - 0.18 11.3 6.5 0.37 10.3 6.5 1.4 1 0 0 1 1 1 0 PPP4R2 Cwf_Cwc_15 PF04889.12 KXH48576.1 - 1.1 9.0 12.6 0.17 11.6 7.9 2.0 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein DNA_pol_phi PF04931.13 KXH48576.1 - 3.5 5.6 16.0 6.1 4.8 16.0 1.3 1 0 0 1 1 1 0 DNA polymerase phi MFS_1 PF07690.16 KXH48577.1 - 4e-34 118.1 53.5 4.2e-25 88.4 22.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2975 PF11188.8 KXH48577.1 - 0.019 14.8 0.0 0.019 14.8 0.0 4.2 3 2 1 4 4 4 0 Protein of unknown function (DUF2975) MFS_1_like PF12832.7 KXH48577.1 - 0.049 12.5 0.1 0.049 12.5 0.1 3.2 2 1 0 3 3 3 0 MFS_1 like family Enterotoxin_a PF01375.17 KXH48578.1 - 1.3e-45 156.0 0.2 1.7e-45 155.7 0.2 1.0 1 0 0 1 1 1 1 Heat-labile enterotoxin alpha chain Methyltransf_16 PF10294.9 KXH48580.1 - 1.5e-09 37.9 0.0 0.00029 20.6 0.0 2.2 2 0 0 2 2 2 2 Lysine methyltransferase Methyltransf_12 PF08242.12 KXH48580.1 - 0.16 12.7 0.0 29 5.5 0.0 2.7 2 1 0 2 2 2 0 Methyltransferase domain DUF515 PF04415.12 KXH48580.1 - 0.37 9.1 2.5 0.66 8.3 2.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Aconitase PF00330.20 KXH48581.1 - 4e-160 533.8 0.0 6.5e-160 533.1 0.0 1.3 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KXH48581.1 - 3.4e-39 134.2 0.0 6.7e-39 133.2 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain MCM_N PF14551.6 KXH48583.1 - 0.087 13.4 0.0 0.18 12.4 0.0 1.5 1 0 0 1 1 1 0 MCM N-terminal domain DUF2418 PF10332.9 KXH48584.1 - 1.2e-39 134.7 0.7 2.2e-38 130.7 0.8 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF2418) ATP-synt_F PF01990.17 KXH48585.1 - 2.6e-34 117.4 0.1 3e-34 117.2 0.1 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit E1_DerP2_DerF2 PF02221.15 KXH48586.1 - 3.9e-28 98.5 0.7 4.7e-28 98.3 0.7 1.1 1 0 0 1 1 1 1 ML domain Big_9 PF17963.1 KXH48586.1 - 0.029 15.1 0.1 0.057 14.2 0.0 1.5 2 0 0 2 2 2 0 Bacterial Ig domain PHD PF00628.29 KXH48587.1 - 2.3e-07 30.6 9.7 4.5e-07 29.6 9.7 1.5 1 0 0 1 1 1 1 PHD-finger SET PF00856.28 KXH48587.1 - 5.4e-05 23.6 0.4 0.00019 21.8 0.0 2.1 2 1 0 2 2 2 1 SET domain Glycos_transf_4 PF00953.21 KXH48588.1 - 1.4e-28 99.9 8.5 1.4e-28 99.9 8.5 2.1 3 0 0 3 3 3 1 Glycosyl transferase family 4 MFS_1 PF07690.16 KXH48589.1 - 4.7e-46 157.3 38.5 4.7e-46 157.3 38.5 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH48589.1 - 8.6e-14 51.2 8.5 8.6e-14 51.2 8.5 2.0 1 1 0 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 KXH48589.1 - 4.2e-06 26.3 2.6 4.2e-06 26.3 2.6 1.9 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB TRI12 PF06609.13 KXH48589.1 - 2.8e-05 22.8 1.3 4.2e-05 22.2 1.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Transglut_core PF01841.19 KXH48590.1 - 3e-08 34.1 0.1 6.6e-08 33.0 0.1 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily Gln_amidase PF15644.6 KXH48590.1 - 0.047 14.7 0.0 0.14 13.2 0.0 1.9 1 1 0 1 1 1 0 Papain fold toxin 1, glutamine deamidase F-box-like PF12937.7 KXH48591.1 - 4.8e-07 29.6 0.4 9.7e-07 28.6 0.4 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXH48591.1 - 2.4e-06 27.2 0.1 6.7e-06 25.9 0.1 1.6 1 0 0 1 1 1 1 F-box domain Spc7 PF08317.11 KXH48591.1 - 0.0012 17.8 2.8 0.0012 17.8 2.8 2.1 2 0 0 2 2 2 1 Spc7 kinetochore protein PilJ PF13675.6 KXH48591.1 - 0.012 15.6 0.9 0.055 13.5 0.9 2.2 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term FTA4 PF13093.6 KXH48591.1 - 0.014 15.3 1.6 0.028 14.3 1.6 1.6 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 UPF0242 PF06785.11 KXH48591.1 - 0.018 15.2 0.8 0.045 13.9 0.8 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus F-box-like_2 PF13013.6 KXH48591.1 - 0.025 14.6 0.0 0.066 13.2 0.0 1.8 1 0 0 1 1 1 0 F-box-like domain DUF5082 PF16888.5 KXH48591.1 - 0.065 13.5 0.6 0.2 11.9 0.6 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) Glycos_transf_1 PF00534.20 KXH48591.1 - 0.11 12.1 0.0 0.25 10.9 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferases group 1 Fib_alpha PF08702.10 KXH48591.1 - 0.12 12.5 0.2 0.55 10.4 0.2 2.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Bacillus_HBL PF05791.11 KXH48591.1 - 0.15 11.9 0.9 0.35 10.7 0.9 1.5 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) Sec34 PF04136.15 KXH48591.1 - 0.4 10.6 2.4 6.7 6.6 0.8 2.5 1 1 1 2 2 2 0 Sec34-like family COG2 PF06148.11 KXH48591.1 - 0.41 10.7 1.9 3 7.9 0.1 3.1 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DivIC PF04977.15 KXH48591.1 - 0.87 9.4 5.9 10 6.0 0.8 2.7 1 1 1 2 2 2 0 Septum formation initiator Baculo_PEP_C PF04513.12 KXH48591.1 - 0.95 9.5 5.3 0.13 12.3 0.9 1.8 2 0 0 2 2 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus PARM PF17061.5 KXH48591.1 - 2.1 8.4 20.9 3.8 7.6 20.9 1.3 1 0 0 1 1 1 0 PARM DegS PF05384.11 KXH48591.1 - 2.3 7.7 8.3 0.68 9.4 2.5 2.5 2 0 0 2 2 2 0 Sensor protein DegS DUF2203 PF09969.9 KXH48591.1 - 5.2 7.8 5.7 2.3 9.0 1.1 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) TFIIB PF00382.19 KXH48593.1 - 0.00068 19.6 0.0 1.1 9.3 0.0 2.5 2 0 0 2 2 2 2 Transcription factor TFIIB repeat Cyclin_N PF00134.23 KXH48593.1 - 0.0034 17.1 0.0 0.077 12.7 0.0 2.3 2 0 0 2 2 2 1 Cyclin, N-terminal domain Vps5 PF09325.10 KXH48594.1 - 3.1e-11 43.3 1.7 5.2e-11 42.5 1.7 1.2 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 KXH48594.1 - 1.7e-10 40.9 0.0 3.7e-10 39.8 0.0 1.6 1 0 0 1 1 1 1 PX domain NST1 PF13945.6 KXH48594.1 - 0.33 11.1 4.3 0.11 12.6 1.3 1.7 2 0 0 2 2 2 0 Salt tolerance down-regulator ADH_N PF08240.12 KXH48595.1 - 4.8e-27 94.0 1.5 1e-26 93.0 1.5 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXH48595.1 - 8.4e-18 64.6 0.2 8.4e-13 48.4 0.0 2.3 2 0 0 2 2 2 2 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KXH48595.1 - 5.9e-09 35.7 0.8 0.00016 21.2 0.1 2.6 2 1 0 2 2 2 2 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 KXH48595.1 - 0.00072 18.9 0.5 0.0013 18.1 0.5 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 KXH48595.1 - 0.0033 17.0 0.7 0.0059 16.2 0.2 1.6 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ADH_zinc_N_2 PF13602.6 KXH48595.1 - 0.0042 18.1 0.0 0.011 16.8 0.0 1.9 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ThiF PF00899.21 KXH48595.1 - 0.022 14.1 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 ThiF family NAD_binding_8 PF13450.6 KXH48595.1 - 0.034 14.4 1.5 0.085 13.1 0.6 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXH48595.1 - 0.035 13.3 0.2 0.082 12.1 0.1 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 KXH48595.1 - 0.039 13.6 0.0 0.064 12.9 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 KXH48595.1 - 0.049 13.5 0.2 0.076 12.9 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NADH_4Fe-4S PF10589.9 KXH48595.1 - 0.062 13.4 0.8 0.18 11.9 0.5 1.9 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region Shikimate_DH PF01488.20 KXH48595.1 - 0.067 13.2 0.1 0.14 12.2 0.1 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF281 PF03436.13 KXH48595.1 - 0.087 13.2 0.8 1.6 9.2 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF281) TrkA_N PF02254.18 KXH48595.1 - 0.11 12.8 0.1 0.19 12.0 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain MitMem_reg PF13012.6 KXH48596.1 - 2e-10 41.0 1.1 7.5e-10 39.2 1.1 1.9 1 1 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 KXH48596.1 - 2.2e-05 24.4 0.0 5.1e-05 23.2 0.0 1.6 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Cytochrom_c3_2 PF14537.6 KXH48598.1 - 0.0024 18.3 3.6 0.003 18.0 3.6 1.2 1 0 0 1 1 1 1 Cytochrome c3 Cu_amine_oxid PF01179.20 KXH48632.1 - 4.4e-166 552.9 0.0 5.4e-166 552.5 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.16 KXH48632.1 - 8.8e-11 41.9 0.1 1.6e-10 41.1 0.1 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.16 KXH48632.1 - 0.0021 18.4 0.0 0.0049 17.2 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain SelK_SelG PF10961.8 KXH48634.1 - 0.11 13.1 0.1 0.11 13.1 0.1 2.7 3 0 0 3 3 3 0 Selenoprotein SelK_SelG FAD_binding_4 PF01565.23 KXH48635.1 - 4.2e-23 81.6 3.3 4.9e-23 81.4 1.0 2.2 1 1 1 2 2 2 1 FAD binding domain BBE PF08031.12 KXH48635.1 - 5e-07 29.7 0.0 9.6e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like Lactamase_B PF00753.27 KXH48636.1 - 1.2e-19 71.2 3.6 2.5e-19 70.1 3.6 1.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KXH48636.1 - 2e-06 27.5 0.0 3.1e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain MDH PF02315.16 KXH48636.1 - 0.12 12.4 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Methanol dehydrogenase beta subunit Lipase_GDSL_2 PF13472.6 KXH48637.1 - 2.7e-11 44.2 0.4 3.5e-11 43.8 0.4 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KXH48637.1 - 0.0005 20.1 0.0 0.00064 19.8 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase ADH_zinc_N PF00107.26 KXH48638.1 - 1.3e-21 76.9 5.7 1.4e-21 76.9 0.6 3.1 3 1 0 4 4 4 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXH48638.1 - 9.9e-20 70.5 1.7 1.7e-19 69.7 1.7 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KXH48638.1 - 1.8e-05 25.8 1.0 4.8e-05 24.4 0.8 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase SKG6 PF08693.10 KXH48641.1 - 0.0045 16.4 3.0 0.014 14.8 3.0 1.9 1 0 0 1 1 1 1 Transmembrane alpha-helix domain stn_TNFRSF12A PF12191.8 KXH48641.1 - 0.0049 17.1 0.1 0.0096 16.1 0.1 1.6 1 0 0 1 1 1 1 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Adeno_E3_CR2 PF02439.15 KXH48641.1 - 0.042 13.6 0.0 0.082 12.7 0.0 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 CcmD PF04995.14 KXH48641.1 - 0.3 11.2 2.7 0.49 10.5 2.7 1.3 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) ASFV_J13L PF05568.11 KXH48641.1 - 3.1 7.5 10.0 3 7.6 0.0 3.4 1 1 3 4 4 4 0 African swine fever virus J13L protein Granulin PF00396.18 KXH48641.1 - 3.9 7.9 6.3 0.73 10.2 1.3 2.1 2 0 0 2 2 2 0 Granulin FGF-BP1 PF06473.12 KXH48642.1 - 1.3 8.8 6.7 1.7 8.4 6.7 1.1 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) TMEM214 PF10151.9 KXH48642.1 - 2.7 6.3 5.3 3.2 6.1 5.3 1.0 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator DUF4419 PF14388.6 KXH48643.1 - 3.5e-55 187.6 1.5 6e-33 114.5 0.8 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4419) DUF4124 PF13511.6 KXH48643.1 - 0.28 11.6 0.9 0.6 10.5 0.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4124) Enterotoxin_a PF01375.17 KXH48645.1 - 7.2e-48 163.4 1.5 8.4e-48 163.2 1.5 1.0 1 0 0 1 1 1 1 Heat-labile enterotoxin alpha chain DUF4572 PF15139.6 KXH48646.1 - 0.023 14.6 0.2 0.068 13.1 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4572) DUF327 PF03885.13 KXH48646.1 - 0.036 14.0 0.0 0.081 12.9 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF327) DUF3747 PF12565.8 KXH48646.1 - 0.039 13.3 0.0 0.063 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3747) DUF2773 PF10971.8 KXH48646.1 - 0.055 13.6 0.2 6.2 7.0 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2773) PLAC8 PF04749.17 KXH48647.1 - 8.6e-23 81.2 11.7 1.1e-22 80.9 11.7 1.1 1 0 0 1 1 1 1 PLAC8 family FAD_binding_4 PF01565.23 KXH48648.1 - 3.7e-25 88.3 5.4 3.7e-25 88.3 5.4 1.5 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 KXH48648.1 - 0.0012 18.9 0.1 0.0052 16.9 0.0 2.0 2 0 0 2 2 2 1 Berberine and berberine like HgmA PF04209.13 KXH48649.1 - 2.2e-167 557.1 0.0 2.6e-167 556.9 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase p450 PF00067.22 KXH48650.1 - 5.6e-74 249.5 0.0 6.3e-74 249.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.18 KXH48651.1 - 5.1e-05 22.4 0.3 6.7e-05 22.0 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain COesterase PF00135.28 KXH48652.1 - 4.7e-58 197.3 0.0 6.2e-58 196.9 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXH48652.1 - 1.3e-06 28.5 0.1 2.5e-05 24.2 0.1 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXH48652.1 - 0.0015 19.2 0.0 0.0031 18.1 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.28 KXH48653.1 - 4.2e-56 190.9 0.0 2.1e-55 188.6 0.0 1.8 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXH48653.1 - 2.1e-07 31.0 0.1 4.7e-06 26.6 0.1 2.3 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXH48653.1 - 0.013 16.2 0.7 0.018 15.7 0.7 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family FAD_binding_3 PF01494.19 KXH48654.1 - 1.2e-45 156.3 0.0 1.6e-45 155.9 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KXH48654.1 - 0.013 14.7 0.0 0.025 13.8 0.0 1.5 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXH48654.1 - 0.25 10.5 0.1 2.1 7.6 0.3 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SET PF00856.28 KXH48655.1 - 1.4e-08 35.3 0.0 1.4e-07 32.0 0.0 2.1 1 1 1 2 2 2 1 SET domain TFR_dimer PF04253.15 KXH48657.1 - 2.8e-30 104.9 0.0 5e-30 104.1 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 KXH48657.1 - 9.3e-16 58.1 0.0 1.9e-15 57.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KXH48657.1 - 1.6e-13 50.5 0.3 3.5e-13 49.4 0.3 1.6 1 0 0 1 1 1 1 PA domain SP_C-Propep PF08999.10 KXH48657.1 - 0.11 12.3 0.0 0.27 11.0 0.0 1.6 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide Vps35 PF03635.17 KXH48658.1 - 0 1023.8 0.0 0 1023.7 0.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 BRCT_2 PF16589.5 KXH48690.1 - 1.6e-06 28.4 0.0 2.8e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 KXH48690.1 - 0.00019 21.3 0.3 0.00065 19.6 0.1 1.9 2 0 0 2 2 2 1 twin BRCT domain LIG3_BRCT PF16759.5 KXH48690.1 - 0.0092 16.2 0.0 0.053 13.8 0.0 2.1 2 0 0 2 2 2 1 DNA ligase 3 BRCT domain Ribosomal_60s PF00428.19 KXH48690.1 - 0.012 16.2 2.2 0.057 14.0 2.2 2.0 2 0 0 2 2 2 0 60s Acidic ribosomal protein RVT_3 PF13456.6 KXH48690.1 - 0.12 12.1 0.1 0.24 11.2 0.1 1.5 1 0 0 1 1 1 0 Reverse transcriptase-like AMP-binding PF00501.28 KXH48691.1 - 1.1e-72 245.0 0.0 1.3e-72 244.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 KXH48691.1 - 5.3e-19 67.9 0.4 5.3e-19 67.9 0.4 2.3 3 0 0 3 3 3 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 KXH48691.1 - 2.6e-17 63.6 0.0 6.9e-17 62.2 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Mucin15 PF15672.5 KXH48692.1 - 0.063 12.7 2.8 0.073 12.5 2.8 1.0 1 0 0 1 1 1 0 Cell-membrane associated Mucin15 ADH_zinc_N PF00107.26 KXH48693.1 - 1.2e-25 90.0 0.3 2e-25 89.3 0.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXH48693.1 - 4.3e-21 76.4 0.0 6.7e-21 75.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXH48693.1 - 1.1e-08 34.9 0.0 2.6e-07 30.5 0.0 2.4 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain CFEM PF05730.11 KXH48694.1 - 0.00048 20.2 1.0 0.00048 20.2 1.0 1.7 2 0 0 2 2 2 1 CFEM domain DLH PF01738.18 KXH48695.1 - 1.2e-20 74.0 0.0 7.9e-19 68.1 0.0 2.3 1 1 0 1 1 1 1 Dienelactone hydrolase family Rep_fac-A_C PF08646.10 KXH48696.1 - 4.1e-57 192.0 5.9 3.6e-56 189.0 3.6 2.4 2 0 0 2 2 2 1 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 KXH48696.1 - 6e-39 131.9 1.9 2.6e-38 129.9 0.5 2.6 3 0 0 3 3 3 1 Replication protein A OB domain Rep-A_N PF04057.12 KXH48696.1 - 2.6e-24 85.1 0.1 6.4e-24 83.9 0.1 1.7 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.25 KXH48696.1 - 6.3e-16 58.1 0.8 6.4e-10 38.9 0.0 4.4 4 1 1 5 5 5 2 OB-fold nucleic acid binding domain CDC24_OB3 PF17244.2 KXH48696.1 - 0.00048 19.9 0.7 0.022 14.5 0.1 2.7 3 0 0 3 3 3 1 Cell division control protein 24, OB domain 3 DUF5521 PF17659.1 KXH48696.1 - 0.077 10.8 1.4 0.6 7.9 0.1 2.5 2 1 0 2 2 2 0 Family of unknown function (DUF5521) DUF4539 PF15072.6 KXH48696.1 - 0.078 13.0 0.0 3.2 7.9 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4539) DUF4957 PF16318.5 KXH48696.1 - 1.4 8.9 4.0 1.9 8.4 0.4 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4957) PCI PF01399.27 KXH48697.1 - 0.016 15.7 0.2 0.11 13.0 0.0 2.3 2 0 0 2 2 2 0 PCI domain Amidohydro_1 PF01979.20 KXH48698.1 - 9.4e-05 21.9 1.0 0.00041 19.8 1.0 1.9 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_2 PF04909.14 KXH48698.1 - 0.00056 19.8 0.0 0.00082 19.2 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase TatD_DNase PF01026.21 KXH48698.1 - 0.098 12.0 0.2 0.32 10.4 0.2 1.8 1 1 0 1 1 1 0 TatD related DNase SpoU_methylase PF00588.19 KXH48700.1 - 5.8e-27 94.6 0.0 9e-27 94.0 0.0 1.3 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 KXH48700.1 - 6.3e-11 42.4 0.0 1.4e-10 41.3 0.0 1.6 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding Arginase PF00491.21 KXH48703.1 - 5.1e-91 305.0 0.0 6.7e-91 304.7 0.0 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 KXH48703.1 - 0.083 13.1 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 UPF0489 domain DUF1589 PF07628.11 KXH48703.1 - 0.15 12.1 0.0 0.8 9.8 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1589) zf-U1 PF06220.12 KXH48705.1 - 6.3e-22 77.1 3.4 9.3e-22 76.5 3.4 1.3 1 0 0 1 1 1 1 U1 zinc finger EMP24_GP25L PF01105.24 KXH48706.1 - 3.1e-41 141.3 0.0 3.8e-41 141.0 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF4164 PF13747.6 KXH48706.1 - 0.016 15.5 0.4 0.025 14.8 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) EzrA PF06160.12 KXH48706.1 - 0.087 11.0 0.9 0.11 10.6 0.9 1.0 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Sdh5 PF03937.16 KXH48707.1 - 1.3e-23 82.7 0.2 3.7e-23 81.3 0.2 1.7 2 0 0 2 2 2 1 Flavinator of succinate dehydrogenase RAP1 PF07218.11 KXH48707.1 - 0.15 10.3 1.2 0.16 10.2 1.2 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) PI3K_1B_p101 PF10486.9 KXH48707.1 - 0.43 8.3 1.6 0.54 8.0 1.6 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit MIS13 PF08202.11 KXH48708.1 - 2.7e-59 200.9 1.3 5e-59 200.0 1.3 1.4 1 0 0 1 1 1 1 Mis12-Mtw1 protein family RNA_pol_Rpb4 PF03874.16 KXH48708.1 - 0.098 13.0 0.4 0.24 11.7 0.4 1.7 1 1 0 1 1 1 0 RNA polymerase Rpb4 ZapB PF06005.12 KXH48708.1 - 0.43 11.0 8.1 1.9 9.0 0.1 2.5 2 0 0 2 2 2 0 Cell division protein ZapB Aft1_HRR PF11787.8 KXH48709.1 - 2.7e-24 86.1 17.1 2.7e-24 86.1 17.1 4.6 5 1 0 5 5 5 1 Aft1 HRR domain Aft1_HRA PF11786.8 KXH48709.1 - 6.6e-24 84.0 10.0 6.6e-24 84.0 10.0 2.8 3 0 0 3 3 3 1 Aft1 HRA domain Aft1_OSA PF11785.8 KXH48709.1 - 3.1e-20 72.4 7.1 3.1e-20 72.4 7.1 5.3 5 0 0 5 5 5 1 Aft1 osmotic stress response (OSM) domain bZIP_1 PF00170.21 KXH48709.1 - 1.5e-12 47.4 6.2 2.3e-12 46.8 6.2 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KXH48709.1 - 4.8e-06 26.6 6.2 9.1e-06 25.7 6.2 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KXH48709.1 - 0.0028 18.1 2.9 0.0028 18.1 2.9 2.3 2 0 0 2 2 2 1 bZIP Maf transcription factor HALZ PF02183.18 KXH48709.1 - 0.13 12.5 0.1 0.25 11.6 0.1 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper ATF7IP_BD PF16788.5 KXH48709.1 - 9.4 6.3 14.7 10 6.2 2.8 2.6 2 1 0 2 2 2 0 ATF-interacting protein binding domain GST_N_3 PF13417.6 KXH48710.1 - 1.9e-09 37.8 0.2 3.9e-09 36.8 0.2 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KXH48710.1 - 5.2e-06 26.4 0.0 8.6e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KXH48710.1 - 3.5e-05 23.9 0.0 5.9e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KXH48710.1 - 0.00013 22.2 0.1 0.00039 20.6 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain SCP1201-deam PF14428.6 KXH48710.1 - 0.088 12.7 0.0 0.27 11.1 0.0 1.8 2 0 0 2 2 2 0 SCP1.201-like deaminase DUF150_C PF17384.2 KXH48710.1 - 0.11 12.6 0.0 0.47 10.6 0.0 2.0 3 0 0 3 3 3 0 RimP C-terminal SH3 domain GST_C_3 PF14497.6 KXH48710.1 - 0.17 12.1 0.0 0.3 11.3 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain p450 PF00067.22 KXH48711.1 - 2.4e-43 148.6 0.0 3.1e-43 148.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 CDT1_C PF16679.5 KXH48712.1 - 2e-19 69.8 0.3 2e-19 69.8 0.3 2.6 3 1 0 3 3 3 1 DNA replication factor Cdt1 C-terminal domain HTH_3 PF01381.22 KXH48713.1 - 4e-11 42.8 0.0 5.7e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix MBF1 PF08523.10 KXH48713.1 - 0.00017 22.0 0.0 0.00042 20.7 0.0 1.7 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_31 PF13560.6 KXH48713.1 - 0.007 16.7 0.0 0.0096 16.2 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain MRP-L27 PF09809.9 KXH48713.1 - 0.0074 16.1 0.0 0.0086 15.9 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 HTH_37 PF13744.6 KXH48713.1 - 0.084 12.8 0.1 0.15 12.0 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Microvir_H PF04687.12 KXH48714.1 - 1.4e-166 553.5 16.6 2.1e-166 552.9 16.6 1.2 1 0 0 1 1 1 1 Microvirus H protein (pilot protein) Phage_GPA PF05840.13 KXH48714.1 - 1.5e-46 158.9 0.0 1.5e-46 158.9 0.0 2.8 2 1 1 3 3 3 1 Bacteriophage replication gene A protein (GPA) Phage_F PF02305.17 KXH48715.1 - 1.5e-160 535.4 1.7 2.3e-88 297.2 0.5 2.0 1 1 1 2 2 2 2 Capsid protein (F protein) KNOX2 PF03791.13 KXH48715.1 - 0.064 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 KNOX2 domain CwfJ_C_1 PF04677.15 KXH48782.1 - 1.3e-23 83.1 0.0 2.3e-23 82.4 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 KXH48782.1 - 8.4e-15 55.5 1.8 1.6e-14 54.5 1.2 1.8 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 2 DRIM PF07539.12 KXH48783.1 - 3.2e-204 679.8 6.6 5.1e-204 679.1 4.7 2.5 2 0 0 2 2 2 1 Down-regulated in metastasis HEAT PF02985.22 KXH48783.1 - 0.00037 20.5 2.1 11 6.6 0.1 6.5 7 0 0 7 7 7 2 HEAT repeat CNOT11 PF10155.9 KXH48783.1 - 1.8 8.7 4.3 54 4.0 1.1 4.2 4 0 0 4 4 4 0 CCR4-NOT transcription complex subunit 11 V-ATPase_H_C PF11698.8 KXH48783.1 - 2 8.5 6.1 33 4.6 0.0 5.2 4 0 0 4 4 4 0 V-ATPase subunit H zf-DNL PF05180.12 KXH48784.1 - 4.1e-28 97.1 0.3 5.6e-28 96.7 0.3 1.2 1 0 0 1 1 1 1 DNL zinc finger JHY PF15261.6 KXH48784.1 - 0.088 13.5 0.6 0.14 12.9 0.6 1.3 1 0 0 1 1 1 0 Jhy protein zf-CSL PF05207.13 KXH48784.1 - 0.17 11.6 0.3 0.3 10.8 0.3 1.3 1 0 0 1 1 1 0 CSL zinc finger Cullin PF00888.22 KXH48785.1 - 1.1e-198 661.8 6.9 1.1e-198 661.8 6.9 1.3 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.9 KXH48785.1 - 9.3e-27 92.9 0.9 2.8e-26 91.3 0.9 1.9 1 0 0 1 1 1 1 Cullin protein neddylation domain RGS PF00615.19 KXH48785.1 - 0.0095 16.2 0.4 0.029 14.6 0.4 1.9 1 0 0 1 1 1 1 Regulator of G protein signaling domain MA3 PF02847.17 KXH48785.1 - 0.027 14.4 0.4 0.19 11.8 0.0 2.5 2 0 0 2 2 2 0 MA3 domain DUF3405 PF11885.8 KXH48785.1 - 0.032 12.9 0.2 0.087 11.4 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3405) HEPN_DZIP3 PF18738.1 KXH48785.1 - 0.039 13.7 0.4 1.1 9.0 0.0 2.6 2 0 0 2 2 2 0 DZIP3/ hRUL138-like HEPN Zn_clus PF00172.18 KXH48805.1 - 0.017 15.2 5.1 0.027 14.6 5.1 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXH48806.1 - 3.9e-15 55.6 0.4 4.2e-14 52.2 0.4 2.2 1 1 0 1 1 1 1 Fungal specific transcription factor domain SPX PF03105.19 KXH48806.1 - 0.039 13.9 5.6 20 5.0 8.0 2.5 2 1 0 2 2 2 0 SPX domain Ldh_1_N PF00056.23 KXH48807.1 - 3.6e-44 150.3 0.2 5.1e-44 149.8 0.2 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 KXH48807.1 - 4.7e-42 143.8 0.0 6.9e-42 143.2 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.19 KXH48807.1 - 3.7e-06 26.2 0.0 5.8e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KXH48807.1 - 0.0062 16.4 0.1 0.011 15.6 0.1 1.5 1 0 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 KXH48807.1 - 0.037 14.4 0.1 0.19 12.2 0.1 2.0 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.13 KXH48807.1 - 0.046 13.3 0.0 0.088 12.3 0.0 1.5 1 1 0 1 1 1 0 NmrA-like family Iso_dh PF00180.20 KXH48808.1 - 4.7e-85 285.8 0.0 5.6e-85 285.5 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase BRD4_CDT PF17105.5 KXH48810.1 - 0.044 13.4 0.0 0.08 12.6 0.0 1.3 1 0 0 1 1 1 0 C-terminal domain of bromodomain protein 4 DUF805 PF05656.14 KXH48810.1 - 1.7 9.1 10.4 7.8 7.0 10.4 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF805) zf-C2H2 PF00096.26 KXH48842.1 - 0.0013 19.1 0.2 0.0013 19.1 0.2 1.9 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 KXH48842.1 - 0.063 13.0 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 KXH48842.1 - 0.16 12.9 1.8 0.19 12.6 0.2 2.0 2 0 0 2 2 2 0 C2H2-type zinc finger RgpF PF05045.12 KXH48846.1 - 0.0096 14.7 0.1 0.035 12.9 0.0 1.8 2 0 0 2 2 2 1 Rhamnan synthesis protein F CCSAP PF15748.5 KXH48846.1 - 0.1 12.7 13.6 0.15 12.2 13.6 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Apt1 PF10351.9 KXH48846.1 - 0.21 10.4 7.3 0.29 10.0 7.3 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Presenilin PF01080.17 KXH48846.1 - 0.26 10.0 1.6 0.38 9.5 1.6 1.2 1 0 0 1 1 1 0 Presenilin TMA7 PF09072.10 KXH48846.1 - 0.29 12.0 4.9 0.61 11.0 4.9 1.5 1 0 0 1 1 1 0 Translation machinery associated TMA7 Mucin PF01456.17 KXH48846.1 - 1.8 8.6 13.7 1.8 8.5 1.0 2.2 2 0 0 2 2 2 0 Mucin-like glycoprotein DUF2981 PF11200.8 KXH48846.1 - 2.8 7.6 5.2 4.5 6.9 5.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) SnoaL PF07366.12 KXH48847.1 - 4.5e-06 26.5 0.0 9.1e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 KXH48847.1 - 0.00014 22.4 0.1 0.00028 21.5 0.1 1.5 1 0 0 1 1 1 1 SnoaL-like domain DLH PF01738.18 KXH48847.1 - 0.00037 20.1 0.0 0.0011 18.5 0.0 1.8 2 0 0 2 2 2 1 Dienelactone hydrolase family Gate PF07670.14 KXH48848.1 - 0.1 12.9 3.1 0.45 10.8 3.1 2.1 1 1 0 1 1 1 0 Nucleoside recognition UPF0182 PF03699.13 KXH48848.1 - 0.34 9.0 6.1 0.62 8.1 6.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) Abhydrolase_6 PF12697.7 KXH48849.1 - 2.2e-15 57.9 0.3 2.8e-15 57.5 0.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXH48849.1 - 0.0014 18.4 0.1 0.16 11.6 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF900 PF05990.12 KXH48849.1 - 0.052 13.0 0.0 0.074 12.5 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Pkinase PF00069.25 KXH48850.1 - 9.2e-68 228.5 0.0 1.6e-67 227.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXH48850.1 - 2.2e-49 168.1 0.0 3.6e-49 167.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.6 KXH48850.1 - 1.4e-26 92.7 0.0 2.8e-26 91.8 0.0 1.5 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_2 PF07647.17 KXH48850.1 - 4.7e-17 61.8 0.2 1.3e-16 60.4 0.1 1.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KXH48850.1 - 1.7e-15 57.2 0.1 3.2e-15 56.3 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.23 KXH48850.1 - 1.1e-13 51.6 0.1 1.8e-13 50.9 0.1 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Kinase-like PF14531.6 KXH48850.1 - 1.1e-06 28.2 0.0 0.0003 20.2 0.0 2.2 2 0 0 2 2 2 2 Kinase-like SAM_4 PF18017.1 KXH48850.1 - 0.0067 16.4 0.0 0.015 15.2 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Pkinase_fungal PF17667.1 KXH48850.1 - 0.01 14.7 0.0 0.019 13.8 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase SAM_PNT PF02198.16 KXH48850.1 - 0.17 11.8 0.0 0.35 10.9 0.0 1.4 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain PDT PF00800.18 KXH48851.1 - 9e-52 175.5 0.0 1.2e-51 175.1 0.0 1.1 1 0 0 1 1 1 1 Prephenate dehydratase ACT PF01842.25 KXH48851.1 - 3.9e-05 23.3 0.0 0.00016 21.3 0.0 2.0 2 1 0 2 2 2 1 ACT domain Sulfotransfer_3 PF13469.6 KXH48853.1 - 5.9e-06 26.8 0.1 1e-05 26.0 0.1 1.3 1 0 0 1 1 1 1 Sulfotransferase family Mhr1 PF12829.7 KXH48854.1 - 5.5e-35 119.3 0.1 8.9e-35 118.6 0.1 1.3 1 0 0 1 1 1 1 Transcriptional regulation of mitochondrial recombination AAA_2 PF07724.14 KXH48855.1 - 8.5e-48 162.7 0.0 4.3e-46 157.2 0.0 3.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 KXH48855.1 - 1.3e-32 111.8 14.8 9.4e-32 109.0 3.0 3.8 4 0 0 4 4 3 2 AAA lid domain AAA PF00004.29 KXH48855.1 - 1.6e-27 96.5 0.0 1.9e-14 54.2 0.0 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 KXH48855.1 - 5.1e-24 84.1 2.6 1.3e-23 82.9 0.5 2.9 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 KXH48855.1 - 3.4e-16 59.5 0.0 4e-10 39.8 0.0 3.2 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KXH48855.1 - 9.1e-13 48.7 0.0 5.7e-05 23.4 0.0 4.4 2 1 1 3 3 3 2 AAA domain AAA_16 PF13191.6 KXH48855.1 - 4.6e-12 46.6 14.2 7.8e-07 29.6 0.1 5.7 4 3 0 5 5 4 2 AAA ATPase domain Sigma54_activat PF00158.26 KXH48855.1 - 8.5e-10 38.6 0.0 1.2e-06 28.3 0.0 2.8 2 1 0 2 2 2 2 Sigma-54 interaction domain Clp_N PF02861.20 KXH48855.1 - 1.4e-07 31.5 2.6 0.00019 21.5 0.3 4.0 3 0 0 3 3 3 1 Clp amino terminal domain, pathogenicity island component AAA_14 PF13173.6 KXH48855.1 - 1.8e-06 28.0 0.0 0.12 12.4 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 KXH48855.1 - 2e-06 27.5 0.0 0.0073 15.8 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region Mg_chelatase PF01078.21 KXH48855.1 - 2.8e-06 26.9 0.0 0.085 12.2 0.1 3.7 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 KXH48855.1 - 2.9e-06 27.1 0.0 0.065 13.0 0.0 2.8 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_33 PF13671.6 KXH48855.1 - 4.7e-06 26.8 1.0 0.24 11.5 0.0 4.0 2 1 0 2 2 2 2 AAA domain ATPase_2 PF01637.18 KXH48855.1 - 6.4e-06 26.3 7.4 0.03 14.2 0.2 5.0 3 2 1 5 5 5 1 ATPase domain predominantly from Archaea AAA_18 PF13238.6 KXH48855.1 - 8.1e-06 26.4 3.5 0.11 13.0 0.0 4.2 3 1 0 3 3 3 2 AAA domain AAA_3 PF07726.11 KXH48855.1 - 2.5e-05 24.1 0.1 0.88 9.4 0.0 4.2 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KXH48855.1 - 2.8e-05 24.5 0.0 0.37 11.2 0.0 2.9 3 0 0 3 3 2 2 RNA helicase AAA_28 PF13521.6 KXH48855.1 - 3.7e-05 24.0 0.0 0.45 10.7 0.0 3.4 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KXH48855.1 - 0.00013 21.7 0.0 1.1 8.9 0.0 3.3 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 KXH48855.1 - 0.00014 21.9 0.0 0.34 10.9 0.0 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 KXH48855.1 - 0.00015 21.6 0.3 0.54 9.9 0.0 3.5 4 0 0 4 4 3 2 AAA domain RuvB_N PF05496.12 KXH48855.1 - 0.00016 21.5 1.7 2.1 8.0 0.6 4.3 3 1 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain RsgA_GTPase PF03193.16 KXH48855.1 - 0.00043 20.2 0.6 0.39 10.6 0.0 3.1 3 0 0 3 3 2 1 RsgA GTPase T2SSE PF00437.20 KXH48855.1 - 0.00046 19.3 0.0 0.0063 15.6 0.0 2.6 2 0 0 2 2 2 1 Type II/IV secretion system protein ABC_tran PF00005.27 KXH48855.1 - 0.0005 20.6 0.1 0.64 10.5 0.0 3.2 3 0 0 3 3 2 1 ABC transporter NACHT PF05729.12 KXH48855.1 - 0.0015 18.4 0.0 0.21 11.5 0.0 3.0 3 0 0 3 3 2 1 NACHT domain AAA_19 PF13245.6 KXH48855.1 - 0.0021 18.4 3.6 0.18 12.2 0.1 3.9 6 1 0 6 6 2 1 AAA domain ResIII PF04851.15 KXH48855.1 - 0.0023 18.0 0.0 0.34 10.9 0.0 3.5 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Torsin PF06309.11 KXH48855.1 - 0.0024 18.0 0.0 0.013 15.6 0.0 2.1 2 0 0 2 2 2 1 Torsin Roc PF08477.13 KXH48855.1 - 0.0033 17.6 0.0 2.1 8.6 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 KXH48855.1 - 0.0038 16.9 0.0 4.3 7.2 0.0 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain Rad17 PF03215.15 KXH48855.1 - 0.0049 16.8 0.1 4.1 7.3 0.0 3.1 3 0 0 3 3 2 0 Rad17 P-loop domain Zeta_toxin PF06414.12 KXH48855.1 - 0.0049 16.2 0.0 0.54 9.5 0.0 2.7 2 0 0 2 2 2 1 Zeta toxin NTPase_1 PF03266.15 KXH48855.1 - 0.0058 16.6 0.2 0.22 11.4 0.0 3.2 4 0 0 4 4 2 1 NTPase SRP54 PF00448.22 KXH48855.1 - 0.017 14.7 0.0 4.6 6.8 0.0 2.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain DUF815 PF05673.13 KXH48855.1 - 0.021 14.0 0.0 2.3 7.3 0.0 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF815) AAA_15 PF13175.6 KXH48855.1 - 0.022 14.5 1.2 12 5.5 0.3 3.5 4 0 0 4 4 3 0 AAA ATPase domain AAA_25 PF13481.6 KXH48855.1 - 0.025 14.1 1.7 3.5 7.2 0.0 3.5 3 0 0 3 3 3 0 AAA domain ATP_bind_1 PF03029.17 KXH48855.1 - 0.059 13.2 0.0 6.9 6.4 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein KTI12 PF08433.10 KXH48855.1 - 0.059 12.8 3.9 10 5.5 0.0 3.9 4 0 0 4 4 4 0 Chromatin associated protein KTI12 Cytidylate_kin PF02224.18 KXH48855.1 - 0.084 12.6 7.2 36 4.0 0.0 4.3 4 1 1 5 5 4 0 Cytidylate kinase PduV-EutP PF10662.9 KXH48855.1 - 0.097 12.4 0.0 6.9 6.4 0.0 2.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_6 PF12774.7 KXH48855.1 - 0.13 11.2 0.3 5.7 5.8 0.0 3.0 3 0 0 3 3 3 0 Hydrolytic ATP binding site of dynein motor region AAA_23 PF13476.6 KXH48855.1 - 0.19 12.2 17.1 0.36 11.3 0.0 4.3 4 1 0 4 4 2 0 AAA domain Cob_adeno_trans PF01923.18 KXH48855.1 - 0.84 9.8 9.8 0.13 12.4 3.3 2.8 3 0 0 3 3 3 0 Cobalamin adenosyltransferase CbiA PF01656.23 KXH48855.1 - 1.2 9.2 3.8 37 4.4 0.1 3.5 3 2 1 4 4 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain V_ATPase_I PF01496.19 KXH48855.1 - 4.3 5.1 6.3 9.3 4.0 6.1 1.6 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family PUF PF00806.19 KXH48856.1 - 7e-26 88.4 0.0 0.00027 20.5 0.0 5.5 5 0 0 5 5 5 5 Pumilio-family RNA binding repeat RRM_1 PF00076.22 KXH48856.1 - 1.4e-12 47.3 0.0 3.4e-12 46.0 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHD PF00628.29 KXH48857.1 - 2.9e-12 46.3 18.8 2.6e-07 30.4 8.6 2.5 2 0 0 2 2 2 2 PHD-finger zf-HC5HC2H PF13771.6 KXH48857.1 - 0.005 17.1 5.2 0.031 14.5 1.3 2.4 2 0 0 2 2 2 1 PHD-like zinc-binding domain Zf_RING PF16744.5 KXH48857.1 - 0.11 12.6 11.1 0.73 10.0 0.5 2.7 2 0 0 2 2 2 0 KIAA1045 RING finger zf-PHD-like PF15446.6 KXH48857.1 - 3.2 7.3 10.9 5.5 6.6 3.8 2.5 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain Peptidase_M24 PF00557.24 KXH48858.1 - 2.9e-09 36.9 0.0 3.8e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 SNF5 PF04855.12 KXH48859.1 - 1.9e-65 221.0 0.0 1.9e-64 217.7 0.0 2.1 1 1 0 1 1 1 1 SNF5 / SMARCB1 / INI1 INO80_Ies4 PF08193.11 KXH48859.1 - 0.0028 17.7 1.7 0.0028 17.7 1.7 2.8 3 0 0 3 3 3 2 INO80 complex subunit Ies4 GH131_N PF18271.1 KXH48861.1 - 3.8e-65 220.1 5.5 4.4e-65 219.9 5.5 1.0 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain Polysacc_lyase PF14099.6 KXH48861.1 - 0.053 13.4 5.8 0.15 11.9 5.7 1.7 1 1 0 1 1 1 0 Polysaccharide lyase zf-C3HC4_4 PF15227.6 KXH48862.1 - 0.55 10.4 4.1 11 6.2 0.3 2.3 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING MAPEG PF01124.18 KXH48863.1 - 6.1e-14 52.0 2.4 7.1e-14 51.8 2.4 1.1 1 0 0 1 1 1 1 MAPEG family Myb_DNA-bind_6 PF13921.6 KXH48864.1 - 1.5e-15 57.1 0.4 4.3e-15 55.7 0.4 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain HSA PF07529.13 KXH48864.1 - 6.4e-12 45.6 0.4 6.4e-12 45.6 0.4 4.6 4 0 0 4 4 4 1 HSA Myb_DNA-binding PF00249.31 KXH48864.1 - 3.3e-05 24.0 0.2 8.7e-05 22.6 0.2 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Na_H_Exchanger PF00999.21 KXH48865.1 - 3.1e-72 243.5 39.5 4.1e-72 243.1 39.5 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family PepSY_TM PF03929.16 KXH48865.1 - 5.2 6.6 7.7 0.27 10.9 1.8 1.8 2 0 0 2 2 2 0 PepSY-associated TM region MFS_2 PF13347.6 KXH48866.1 - 1.3e-10 40.4 7.9 1.3e-10 40.4 7.9 2.8 3 0 0 3 3 3 2 MFS/sugar transport protein Cytochrom_B561 PF03188.16 KXH48867.1 - 0.26 11.4 7.6 0.57 10.3 7.6 1.6 1 0 0 1 1 1 0 Eukaryotic cytochrome b561 DUF4079 PF13301.6 KXH48867.1 - 1 9.5 16.8 1.9 8.7 2.8 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF4079) FA_desaturase PF00487.24 KXH48867.1 - 7.4 6.3 18.2 11 5.7 6.0 2.3 1 1 1 2 2 2 0 Fatty acid desaturase PS_Dcarbxylase PF02666.15 KXH48868.1 - 2.7e-49 167.5 0.0 3.9e-49 166.9 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase RnfC_N PF13375.6 KXH48868.1 - 0.023 14.6 0.1 5.9 6.9 0.1 2.4 2 0 0 2 2 2 0 RnfC Barrel sandwich hybrid domain CorA PF01544.18 KXH48869.1 - 1.8e-05 24.2 0.0 5.2e-05 22.7 0.0 1.8 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Peptidase_M35 PF02102.15 KXH48871.1 - 1.7e-57 194.9 16.2 2.1e-57 194.7 16.2 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.6 KXH48871.1 - 1.5e-38 132.6 1.1 1.5e-38 132.6 1.1 1.9 1 1 1 2 2 2 1 Lysine-specific metallo-endopeptidase Phage_RpbA PF10789.9 KXH48872.1 - 0.12 12.4 0.7 0.31 11.1 0.7 1.7 1 0 0 1 1 1 0 Phage RNA polymerase binding, RpbA Asn_synthase PF00733.21 KXH48873.1 - 7.5e-18 65.3 0.0 9.7e-18 64.9 0.0 1.1 1 0 0 1 1 1 1 Asparagine synthase Fungal_trans_2 PF11951.8 KXH48874.1 - 1e-06 27.8 0.1 1.4e-06 27.4 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pkinase PF00069.25 KXH48875.1 - 2.9e-69 233.4 1.8 2.6e-68 230.2 1.8 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXH48875.1 - 1e-53 182.3 0.1 2e-53 181.3 0.1 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 KXH48875.1 - 2.6e-24 85.3 0.0 8.6e-24 83.7 0.0 2.0 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.6 KXH48875.1 - 4.4e-07 29.5 0.0 7.2e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like PH_11 PF15413.6 KXH48875.1 - 8e-07 29.4 0.0 2.7e-06 27.8 0.0 2.0 1 0 0 1 1 1 1 Pleckstrin homology domain Pkinase_fungal PF17667.1 KXH48875.1 - 4.8e-06 25.6 1.0 8.2e-06 24.8 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase PH PF00169.29 KXH48875.1 - 0.0018 18.8 0.0 0.0043 17.5 0.0 1.7 1 0 0 1 1 1 1 PH domain Seadorna_VP7 PF07387.11 KXH48875.1 - 0.027 13.5 0.0 0.046 12.8 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Haspin_kinase PF12330.8 KXH48875.1 - 0.036 13.0 0.1 0.062 12.2 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 KXH48875.1 - 0.061 13.2 0.2 0.061 13.2 0.2 2.4 2 1 1 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.14 KXH48875.1 - 0.094 12.1 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family KIND PF16474.5 KXH48875.1 - 0.13 12.2 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 Kinase non-catalytic C-lobe domain G-patch PF01585.23 KXH48951.1 - 2.8e-13 49.5 0.2 8.6e-13 48.0 0.2 1.8 1 0 0 1 1 1 1 G-patch domain RRM_1 PF00076.22 KXH48951.1 - 4.2e-05 23.3 0.1 7.3e-05 22.5 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MtrG PF04210.13 KXH48951.1 - 0.16 11.8 0.6 0.3 10.9 0.6 1.4 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit G PBP_N PF17093.5 KXH48951.1 - 1 9.6 9.1 1.7 8.9 9.1 1.4 1 0 0 1 1 1 0 Penicillin-binding protein N-terminus Recep_L_domain PF01030.24 KXH48952.1 - 0.083 13.0 6.7 0.4 10.8 0.1 4.1 1 1 2 3 3 3 0 Receptor L domain HhH-GPD PF00730.25 KXH48953.1 - 1.7e-13 51.0 0.0 3.2e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein TerB_C PF15615.6 KXH48953.1 - 0.13 12.5 0.2 0.31 11.3 0.2 1.5 1 0 0 1 1 1 0 TerB-C domain PapD-like PF14874.6 KXH48953.1 - 0.17 12.0 0.0 0.33 11.1 0.0 1.4 1 0 0 1 1 1 0 Flagellar-associated PapD-like Anp1 PF03452.14 KXH48954.1 - 3.9e-105 351.0 0.0 4.7e-105 350.7 0.0 1.1 1 0 0 1 1 1 1 Anp1 UCR_14kD PF02271.16 KXH48955.1 - 1.3e-43 147.0 0.1 1.5e-43 146.8 0.1 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Mito_carr PF00153.27 KXH48956.1 - 4.6e-65 215.6 1.0 6.8e-22 77.2 0.0 3.4 2 1 1 3 3 3 3 Mitochondrial carrier protein HET PF06985.11 KXH48957.1 - 2.2e-12 47.5 5.7 1.6e-09 38.2 1.3 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) SLT_beta PF02258.16 KXH48957.1 - 0.15 12.1 0.0 0.32 11.0 0.0 1.5 1 0 0 1 1 1 0 Shiga-like toxin beta subunit AhpC-TSA PF00578.21 KXH48958.1 - 5.1e-25 87.8 0.0 8.1e-25 87.1 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KXH48958.1 - 4e-15 55.8 0.0 6e-15 55.2 0.0 1.3 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.6 KXH48958.1 - 0.00028 21.0 0.0 0.0023 18.0 0.0 2.0 1 1 1 2 2 2 1 AhpC/TSA antioxidant enzyme CI-B14_5a PF07347.12 KXH48959.1 - 0.085 12.7 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) Yae1_N PF09811.9 KXH48960.1 - 2.1e-07 30.5 3.9 2.9e-07 30.1 3.9 1.2 1 0 0 1 1 1 1 Essential protein Yae1, N terminal BRK PF07533.16 KXH48960.1 - 0.011 15.3 0.1 0.019 14.6 0.1 1.3 1 0 0 1 1 1 0 BRK domain RICTOR_phospho PF14665.6 KXH48960.1 - 0.058 13.7 0.5 0.08 13.3 0.5 1.2 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, phosphorylation-site Trns_repr_metal PF02583.17 KXH48960.1 - 0.12 12.7 0.0 0.22 11.9 0.0 1.3 1 0 0 1 1 1 0 Metal-sensitive transcriptional repressor Ribosomal_60s PF00428.19 KXH48960.1 - 0.32 11.6 5.3 2 9.0 0.6 2.1 2 0 0 2 2 2 0 60s Acidic ribosomal protein adh_short_C2 PF13561.6 KXH48961.1 - 1.4e-46 159.0 0.2 9.4e-42 143.2 0.0 2.2 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXH48961.1 - 7.3e-44 149.6 0.0 1.1e-43 149.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXH48961.1 - 7.8e-15 55.2 0.0 1.3e-14 54.6 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXH48961.1 - 0.00049 19.6 0.1 0.0043 16.5 0.1 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 KXH48961.1 - 0.041 13.3 0.0 0.066 12.6 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Acetyltransf_1 PF00583.25 KXH48962.1 - 9.2e-12 45.2 0.0 1.7e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXH48962.1 - 2e-06 27.7 0.1 3.3e-06 27.0 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXH48962.1 - 6e-06 26.1 0.1 1.1e-05 25.3 0.1 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 KXH48962.1 - 9.1e-06 26.0 0.0 1.7e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KXH48962.1 - 0.026 14.6 0.1 0.054 13.6 0.1 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF952 PF06108.12 KXH48962.1 - 0.15 12.1 0.0 2.3 8.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF952) Gag_p12 PF01141.18 KXH48962.1 - 2.1 8.7 4.8 1.9 8.8 0.7 2.2 2 0 0 2 2 2 0 Gag polyprotein, inner coat protein p12 DUF4646 PF15496.6 KXH48963.1 - 0.00026 21.6 0.1 1.3 9.6 0.0 2.8 3 0 0 3 3 3 2 Domain of unknown function (DUF4646) API5 PF05918.11 KXH48963.1 - 0.54 9.0 1.7 0.97 8.2 1.7 1.4 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Selenoprotein_S PF06936.11 KXH48963.1 - 3.5 7.4 6.2 7.6 6.3 6.2 1.5 1 0 0 1 1 1 0 Selenoprotein S (SelS) IF-2B PF01008.17 KXH48964.1 - 5.2e-41 140.7 0.0 1.6e-40 139.1 0.0 1.7 1 1 0 1 1 1 1 Initiation factor 2 subunit family NIF PF03031.18 KXH48965.1 - 2.6e-55 186.5 0.0 3.6e-55 186.0 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF1761 PF08570.10 KXH48966.1 - 3e-23 82.4 1.6 4.7e-23 81.8 0.5 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1761) Ribosomal_L7Ae PF01248.26 KXH48967.1 - 5.4e-22 77.4 0.5 2.3e-21 75.3 0.5 2.0 1 1 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family SAPS PF04499.15 KXH48967.1 - 0.39 9.4 3.3 0.23 10.2 0.1 1.8 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein UcrQ PF02939.16 KXH48968.1 - 8.3e-38 128.2 0.6 9.7e-38 128.0 0.6 1.1 1 0 0 1 1 1 1 UcrQ family Band_7 PF01145.25 KXH48969.1 - 9.7e-25 87.6 7.7 1.9e-24 86.6 7.7 1.5 1 1 0 1 1 1 1 SPFH domain / Band 7 family YdfA_immunity PF12127.8 KXH48969.1 - 0.00071 18.7 5.5 0.00096 18.3 5.5 1.2 1 0 0 1 1 1 1 SigmaW regulon antibacterial DUF3103 PF11301.8 KXH48969.1 - 0.02 13.7 0.2 0.038 12.8 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3103) PknG_rubred PF16919.5 KXH48969.1 - 0.11 12.7 0.1 0.19 11.9 0.1 1.3 1 0 0 1 1 1 0 Protein kinase G rubredoxin domain Atg14 PF10186.9 KXH48969.1 - 0.17 10.9 1.1 0.24 10.4 1.1 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF676 PF05057.14 KXH48971.1 - 1.9e-51 174.7 0.0 3e-51 174.0 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 KXH48971.1 - 1.2e-05 25.3 0.0 1.9e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase PGAP1 PF07819.13 KXH48971.1 - 3e-05 23.9 0.0 0.00037 20.3 0.0 2.2 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 KXH48971.1 - 0.0001 23.0 0.1 0.00086 20.0 0.0 2.1 1 1 1 2 2 2 1 Alpha/beta hydrolase family Lipase_3 PF01764.25 KXH48971.1 - 0.028 14.3 0.0 0.054 13.4 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) LolA_like PF17131.4 KXH48971.1 - 0.038 13.7 0.0 0.065 13.0 0.0 1.3 1 0 0 1 1 1 0 Outer membrane lipoprotein-sorting protein HhH-GPD PF00730.25 KXH48972.1 - 9.7e-17 61.4 0.0 1.7e-16 60.6 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 KXH48972.1 - 1.4e-08 34.2 0.0 3e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif zf-AN1 PF01428.16 KXH48973.1 - 1.2e-12 47.8 5.4 1.2e-12 47.8 5.4 1.6 1 1 0 1 1 1 1 AN1-like Zinc finger Transp_Tc5_C PF04236.15 KXH48973.1 - 1.2 9.5 7.7 0.57 10.6 5.6 1.5 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain Ldl_recept_a PF00057.18 KXH48973.1 - 6.1 7.1 12.4 1.6 9.0 7.2 2.4 2 1 0 2 2 2 0 Low-density lipoprotein receptor domain class A ADH_N PF08240.12 KXH48975.1 - 1e-25 89.7 3.0 1e-25 89.7 3.0 2.2 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXH48975.1 - 1.7e-18 66.8 0.4 3.2e-18 65.9 0.4 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KXH48975.1 - 0.0027 17.2 0.1 0.011 15.3 0.1 1.8 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus Sacchrp_dh_NADP PF03435.18 KXH48975.1 - 0.0093 16.2 0.1 0.018 15.3 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain AlaDh_PNT_C PF01262.21 KXH48975.1 - 0.023 14.0 0.4 0.04 13.2 0.4 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 KXH48975.1 - 0.087 12.4 0.1 0.15 11.6 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Nucleopor_Nup85 PF07575.13 KXH48976.1 - 4.9e-17 61.7 0.0 3.6e-11 42.4 0.0 2.7 2 1 0 2 2 2 2 Nup85 Nucleoporin TFIIA PF03153.13 KXH48976.1 - 0.036 14.1 1.7 0.057 13.4 1.7 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2457 PF10446.9 KXH48976.1 - 0.3 10.2 15.1 0.47 9.6 15.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) HNH PF01844.23 KXH48977.1 - 0.0002 21.4 3.2 0.00054 20.1 3.2 1.8 1 0 0 1 1 1 1 HNH endonuclease DUF2492 PF10678.9 KXH48977.1 - 0.085 13.1 0.1 0.17 12.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2492) PRK PF00485.18 KXH48977.1 - 0.16 11.7 0.2 0.3 10.8 0.2 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Ntox15 PF15604.6 KXH48977.1 - 1.5 8.9 8.8 3 8.0 8.8 1.5 1 0 0 1 1 1 0 Novel toxin 15 Fungal_trans_2 PF11951.8 KXH48978.1 - 2.4e-07 29.9 1.8 1.4e-06 27.4 1.7 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain GATase PF00117.28 KXH48980.1 - 0.029 14.1 0.0 0.044 13.5 0.0 1.3 1 0 0 1 1 1 0 Glutamine amidotransferase class-I GFO_IDH_MocA PF01408.22 KXH48981.1 - 9.1e-16 58.8 0.1 1.9e-15 57.8 0.1 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 KXH48981.1 - 0.0078 16.9 0.1 0.012 16.2 0.1 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 KXH48981.1 - 0.05 13.6 0.6 0.13 12.2 0.6 1.7 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DXP_reductoisom PF02670.16 KXH48981.1 - 0.058 14.1 0.0 0.15 12.8 0.0 1.7 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase HET PF06985.11 KXH48982.1 - 2.8e-10 40.7 3.9 2e-08 34.7 0.1 2.7 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Mito_carr PF00153.27 KXH48983.1 - 7.7e-52 173.2 3.9 3.5e-18 65.3 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PrpF PF04303.13 KXH48984.1 - 3.1e-94 316.0 2.1 1.2e-85 287.7 0.5 2.0 2 0 0 2 2 2 2 PrpF protein Translin PF01997.16 KXH48985.1 - 1.5e-49 168.7 0.0 1.8e-49 168.5 0.0 1.0 1 0 0 1 1 1 1 Translin family DUF1664 PF07889.12 KXH48985.1 - 0.034 14.2 0.5 0.96 9.5 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) ERG4_ERG24 PF01222.17 KXH48986.1 - 1.8e-140 468.5 19.4 2.1e-140 468.3 19.4 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family ATP-synt_C PF00137.21 KXH48987.1 - 2e-34 117.7 32.9 7.6e-22 77.4 14.6 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Ribosomal_L7Ae PF01248.26 KXH48988.1 - 1.6e-24 85.5 0.1 2.1e-24 85.0 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 KXH48988.1 - 0.00067 19.5 0.0 0.001 18.9 0.0 1.2 1 0 0 1 1 1 1 PELOTA RNA binding domain Syja_N PF02383.18 KXH48989.1 - 8.1e-96 321.1 0.0 1.4e-95 320.4 0.0 1.4 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.8 KXH48989.1 - 5.4e-41 138.9 0.0 1.1e-40 138.0 0.0 1.5 1 0 0 1 1 1 1 Inositol phosphatase DUF3896 PF13035.6 KXH48989.1 - 0.23 11.6 0.2 12 6.1 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3896) Methyltransf_34 PF11312.8 KXH48990.1 - 2.5e-109 365.2 0.0 3.5e-109 364.8 0.0 1.2 1 0 0 1 1 1 1 Putative SAM-dependent methyltransferase DUF979 PF06166.12 KXH48990.1 - 0.028 13.6 0.6 0.056 12.6 0.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF979) Transketolase_N PF00456.21 KXH48992.1 - 1.2e-157 524.1 0.0 1.6e-157 523.7 0.0 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 KXH48992.1 - 3.4e-44 150.7 0.0 5.3e-44 150.0 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KXH48992.1 - 2.4e-10 40.4 0.0 4.9e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain DUF5308 PF17233.2 KXH48993.1 - 7e-56 189.0 5.9 8.1e-56 188.8 5.9 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5308) Amidohydro_1 PF01979.20 KXH49013.1 - 9.7e-19 67.9 0.1 1.2e-17 64.3 0.1 2.5 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KXH49013.1 - 4.8e-14 52.7 1.0 2e-10 40.8 0.3 2.7 2 1 0 2 2 2 2 Amidohydrolase family RTA1 PF04479.13 KXH49015.1 - 2.9e-29 102.1 1.6 3.4e-29 101.9 1.6 1.0 1 0 0 1 1 1 1 RTA1 like protein NADH-u_ox-rdase PF10785.9 KXH49015.1 - 0.17 12.6 1.6 0.43 11.3 0.1 2.1 1 1 1 2 2 2 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit Laterosporulin PF17861.1 KXH49016.1 - 0.11 12.9 0.0 0.28 11.6 0.0 1.7 1 0 0 1 1 1 0 Laterosporulin defensin-like peptide Amidase PF01425.21 KXH49017.1 - 9e-94 315.0 0.0 1.3e-93 314.4 0.0 1.2 1 0 0 1 1 1 1 Amidase DUF3693 PF12472.8 KXH49017.1 - 0.16 11.6 0.0 0.36 10.5 0.0 1.5 1 0 0 1 1 1 0 Phage related protein PRP38 PF03371.15 KXH49018.1 - 5.9e-54 182.6 0.0 7.2e-54 182.3 0.0 1.1 1 0 0 1 1 1 1 PRP38 family CBFD_NFYB_HMF PF00808.23 KXH49020.1 - 1.7e-17 63.4 1.5 3e-17 62.6 0.7 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KXH49020.1 - 1.9e-05 25.0 0.4 8.4e-05 22.9 0.0 1.9 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 BBIP10 PF14777.6 KXH49020.1 - 0.044 13.4 1.2 0.23 11.0 0.1 2.5 2 1 0 2 2 2 0 Cilia BBSome complex subunit 10 DUF3656 PF12392.8 KXH49020.1 - 0.078 13.6 0.8 0.13 12.9 0.8 1.4 1 1 0 1 1 1 0 Collagenase Bromo_TP PF07524.13 KXH49020.1 - 0.092 12.8 0.1 0.2 11.7 0.1 1.6 1 1 0 1 1 1 0 Bromodomain associated adh_short PF00106.25 KXH49021.1 - 1.6e-41 141.9 0.7 1.9e-41 141.7 0.7 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXH49021.1 - 1.2e-30 106.9 0.5 1.4e-30 106.6 0.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH49021.1 - 1.2e-10 41.7 0.6 1.5e-10 41.3 0.6 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KXH49021.1 - 2.5e-06 27.5 0.8 3.6e-06 27.0 0.7 1.6 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KXH49021.1 - 0.0016 18.0 0.1 0.0052 16.3 0.1 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KXH49021.1 - 0.0077 15.8 0.4 0.013 15.1 0.4 1.3 1 0 0 1 1 1 1 NmrA-like family Flot PF15975.5 KXH49021.1 - 0.011 15.9 0.1 0.018 15.2 0.1 1.6 1 1 0 1 1 1 0 Flotillin Shikimate_DH PF01488.20 KXH49021.1 - 0.041 13.9 0.1 0.081 13.0 0.1 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 KXH49021.1 - 0.078 13.2 0.2 0.21 11.9 0.1 1.7 2 0 0 2 2 2 0 TrkA-N domain DAO PF01266.24 KXH49022.1 - 6.3e-48 164.1 0.5 7.2e-48 164.0 0.5 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KXH49022.1 - 1.3e-05 25.7 0.0 0.04 14.5 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXH49022.1 - 0.0003 21.0 0.4 0.0012 19.0 0.0 2.3 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXH49022.1 - 0.0016 17.7 0.0 0.61 9.3 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KXH49022.1 - 0.013 14.6 0.0 0.046 12.8 0.0 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein HI0933_like PF03486.14 KXH49022.1 - 0.062 12.0 0.0 0.11 11.2 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein 3HCDH_N PF02737.18 KXH49022.1 - 0.065 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 KXH49022.1 - 0.1 12.2 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DUF3203 PF11462.8 KXH49022.1 - 0.18 12.0 1.0 0.96 9.7 0.1 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3203) COX16 PF14138.6 KXH49024.1 - 1.1e-33 115.6 0.3 1.5e-33 115.1 0.3 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 CorA PF01544.18 KXH49026.1 - 0.018 14.3 5.5 0.076 12.3 5.5 1.9 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF155 PF02582.14 KXH49026.1 - 0.18 11.9 1.3 0.3 11.2 0.7 1.5 1 1 0 1 1 1 0 Uncharacterised ACR, YagE family COG1723 Pkinase PF00069.25 KXH49027.1 - 5.5e-10 39.0 0.0 1.3e-09 37.8 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXH49027.1 - 0.0011 18.3 0.0 0.013 14.8 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase VWA_2 PF13519.6 KXH49027.1 - 0.044 14.4 0.0 0.094 13.4 0.0 1.6 1 0 0 1 1 1 0 von Willebrand factor type A domain DAO PF01266.24 KXH49103.1 - 2.7e-36 125.9 0.1 3.1e-36 125.7 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXH49103.1 - 5.8e-05 22.5 0.0 0.028 13.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXH49103.1 - 0.00022 21.3 0.1 0.58 10.1 0.0 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding Trp_halogenase PF04820.14 KXH49103.1 - 0.0056 15.6 0.0 0.096 11.5 0.0 2.1 2 0 0 2 2 2 1 Tryptophan halogenase NAD_binding_8 PF13450.6 KXH49103.1 - 0.014 15.6 0.0 0.03 14.6 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KXH49103.1 - 0.028 13.5 0.4 0.1 11.6 0.0 1.9 2 0 0 2 2 2 0 FAD binding domain TrkA_N PF02254.18 KXH49103.1 - 0.031 14.5 0.0 0.24 11.6 0.0 2.3 2 0 0 2 2 2 0 TrkA-N domain ApbA PF02558.16 KXH49103.1 - 0.2 11.3 0.0 0.45 10.1 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Herpes_gE PF02480.16 KXH49104.1 - 0.022 13.5 0.1 0.038 12.7 0.1 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E NCU-G1 PF15065.6 KXH49104.1 - 0.24 10.3 0.5 0.39 9.7 0.5 1.3 1 0 0 1 1 1 0 Lysosomal transcription factor, NCU-G1 Sulfatase PF00884.23 KXH49105.1 - 4e-60 203.8 0.0 5.2e-60 203.4 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.6 KXH49105.1 - 8e-06 26.6 0.0 1.7e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase Phosphodiest PF01663.22 KXH49105.1 - 8.1e-05 22.4 0.1 0.01 15.5 0.0 2.1 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase MF_alpha_N PF05436.11 KXH49106.1 - 0.09 12.7 0.0 0.11 12.4 0.0 1.1 1 0 0 1 1 1 0 Mating factor alpha precursor N-terminus NUC173 PF08161.12 KXH49107.1 - 3.4e-81 271.8 2.6 2.5e-78 262.4 0.2 3.6 3 0 0 3 3 3 2 NUC173 domain HEAT_2 PF13646.6 KXH49107.1 - 0.019 15.3 3.4 5.7 7.4 0.2 4.7 4 0 0 4 4 4 0 HEAT repeats DinB_2 PF12867.7 KXH49107.1 - 0.021 15.3 1.1 0.23 12.0 0.0 3.2 4 1 0 4 4 4 0 DinB superfamily HEAT PF02985.22 KXH49107.1 - 0.033 14.4 1.1 4.5 7.8 0.0 4.2 4 0 0 4 4 4 0 HEAT repeat TFCD_C PF12612.8 KXH49107.1 - 0.098 12.5 2.8 7.8 6.3 0.0 4.8 5 2 1 6 6 6 0 Tubulin folding cofactor D C terminal V-SNARE PF05008.15 KXH49108.1 - 1.6e-19 70.0 2.2 1.6e-19 70.0 2.2 1.8 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.8 KXH49108.1 - 2.4e-19 69.4 1.9 2.4e-19 69.4 1.9 2.1 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus FAM76 PF16046.5 KXH49108.1 - 0.014 14.7 0.1 0.022 14.1 0.1 1.3 1 0 0 1 1 1 0 FAM76 protein Sec20 PF03908.13 KXH49108.1 - 0.023 14.6 1.3 0.048 13.6 0.3 2.1 2 2 1 3 3 3 0 Sec20 Spectrin PF00435.21 KXH49108.1 - 0.05 14.1 3.0 0.091 13.3 0.4 2.4 2 1 1 3 3 3 0 Spectrin repeat Fusion_gly PF00523.18 KXH49108.1 - 0.097 10.9 1.9 0.12 10.5 0.6 1.7 2 0 0 2 2 2 0 Fusion glycoprotein F0 SNARE PF05739.19 KXH49108.1 - 0.28 11.2 2.2 0.31 11.1 0.5 2.0 2 0 0 2 2 2 0 SNARE domain Exonuc_VII_L PF02601.15 KXH49108.1 - 0.7 9.4 6.5 1.1 8.7 6.5 1.4 1 1 0 1 1 1 0 Exonuclease VII, large subunit Amino_oxidase PF01593.24 KXH49109.1 - 9.2e-19 68.0 0.0 3.5e-14 52.9 0.0 2.4 2 1 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KXH49109.1 - 1.3e-10 41.3 0.1 2.9e-10 40.2 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXH49109.1 - 7.6e-07 28.6 0.0 0.00021 20.6 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXH49109.1 - 4.6e-05 23.5 0.1 0.11 12.5 0.0 2.7 2 1 0 2 2 2 2 FAD-NAD(P)-binding DAO PF01266.24 KXH49109.1 - 0.0002 21.0 0.1 0.035 13.7 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.14 KXH49109.1 - 0.00055 18.8 0.1 0.28 9.8 0.0 2.3 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_3 PF13738.6 KXH49109.1 - 0.0025 17.1 0.0 0.34 10.1 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KXH49109.1 - 0.016 14.5 0.0 0.027 13.8 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KXH49109.1 - 0.068 12.2 0.1 0.12 11.4 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 KXH49109.1 - 0.13 12.9 0.1 12 6.6 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KXH49109.1 - 0.21 10.6 0.6 0.3 10.1 0.1 1.5 2 0 0 2 2 2 0 Glucose inhibited division protein A CtaG_Cox11 PF04442.14 KXH49110.1 - 1.6e-59 200.3 0.0 2.6e-59 199.6 0.0 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 Ribosomal_L26 PF16906.5 KXH49111.1 - 1.4e-37 128.0 1.7 1.9e-37 127.6 1.7 1.1 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 KXH49111.1 - 1.2e-07 31.4 1.8 2.5e-07 30.4 1.8 1.5 1 0 0 1 1 1 1 KOW motif DUF1223 PF06764.11 KXH49111.1 - 0.017 15.2 0.1 0.019 15.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1223) GHL5 PF14872.6 KXH49111.1 - 0.18 9.8 0.0 0.21 9.6 0.0 1.0 1 0 0 1 1 1 0 Hypothetical glycoside hydrolase 5 Cwf_Cwc_15 PF04889.12 KXH49113.1 - 6.4 6.4 8.4 15 5.3 1.9 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein VSP PF03302.13 KXH49115.1 - 3.8e-05 22.7 1.3 4.3e-05 22.5 0.4 1.4 2 0 0 2 2 2 1 Giardia variant-specific surface protein SKG6 PF08693.10 KXH49115.1 - 0.0011 18.3 0.4 0.0023 17.3 0.4 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF347 PF03988.12 KXH49115.1 - 0.0029 17.7 0.7 0.0065 16.6 0.7 1.6 1 0 0 1 1 1 1 Repeat of Unknown Function (DUF347) NICE-1 PF15845.5 KXH49115.1 - 0.018 15.8 1.0 0.032 15.0 1.0 1.4 1 0 0 1 1 1 0 Cysteine-rich C-terminal 1 family RSN1_TM PF13967.6 KXH49115.1 - 0.027 14.2 0.0 0.056 13.2 0.0 1.4 1 0 0 1 1 1 0 Late exocytosis, associated with Golgi transport GPI-anchored PF10342.9 KXH49115.1 - 0.032 15.0 0.7 0.054 14.3 0.7 1.4 1 0 0 1 1 1 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Ala_racemase_N PF01168.20 KXH49116.1 - 8.8e-20 71.3 0.0 1e-19 71.0 0.0 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Thioredoxin_8 PF13905.6 KXH49116.1 - 0.083 13.2 0.0 0.14 12.5 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like Zn_clus PF00172.18 KXH49117.1 - 1.4e-07 31.5 10.7 2.2e-07 30.9 10.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAP_central PF04928.17 KXH49117.1 - 0.18 10.7 0.0 0.25 10.3 0.0 1.1 1 0 0 1 1 1 0 Poly(A) polymerase central domain HMGL-like PF00682.19 KXH49119.1 - 3e-40 138.4 0.0 9.8e-40 136.8 0.0 1.7 1 1 0 1 1 1 1 HMGL-like ATP-synt_ab PF00006.25 KXH49121.1 - 2.2e-65 220.3 0.0 3.9e-65 219.5 0.0 1.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 KXH49121.1 - 7.6e-15 55.2 0.9 1.6e-14 54.2 0.9 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain DUF5535 PF17687.1 KXH49121.1 - 0.068 13.3 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5535) DUF561 PF04481.12 KXH49121.1 - 0.19 10.9 0.0 0.3 10.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF561) P16-Arc PF04699.14 KXH49122.1 - 1.2e-44 152.3 0.0 4.1e-44 150.7 0.0 1.7 1 1 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) EP400_N PF15790.5 KXH49122.1 - 0.11 11.3 0.0 0.12 11.2 0.0 1.1 1 0 0 1 1 1 0 E1A-binding protein p400, N-terminal DUF2605 PF10792.9 KXH49122.1 - 0.12 12.3 0.1 0.39 10.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2605) Methyltransf_23 PF13489.6 KXH49123.1 - 1.8e-10 40.9 0.0 9.8e-10 38.5 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH49123.1 - 2.7e-09 37.5 0.0 7e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH49123.1 - 1.1e-06 29.2 0.0 2.2e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH49123.1 - 3.1e-06 27.8 0.0 1.4e-05 25.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH49123.1 - 0.0011 18.8 0.0 0.0057 16.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Adaptin_N PF01602.20 KXH49124.1 - 3.6e-123 411.9 10.3 4.7e-123 411.5 10.3 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.16 KXH49124.1 - 4.9e-46 155.6 0.0 1.4e-45 154.1 0.0 1.8 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.20 KXH49124.1 - 4.2e-15 56.0 0.0 7.8e-15 55.1 0.0 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain Proteasom_PSMB PF10508.9 KXH49124.1 - 0.013 14.1 5.4 0.13 10.8 1.9 2.3 2 0 0 2 2 2 0 Proteasome non-ATPase 26S subunit Corona_S2 PF01601.16 KXH49143.1 - 0.59 8.5 2.1 0.68 8.4 2.1 1.0 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein Ank_2 PF12796.7 KXH49144.1 - 2e-57 191.7 1.0 4.3e-11 43.2 0.0 8.7 4 3 5 10 10 10 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXH49144.1 - 8.7e-41 137.8 7.6 9e-05 23.0 0.1 14.2 7 3 8 15 15 15 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXH49144.1 - 4.4e-35 115.7 5.3 0.0064 16.9 0.0 17.6 18 0 0 18 18 18 4 Ankyrin repeat NACHT_N PF17100.5 KXH49144.1 - 1.6e-28 100.1 0.9 2.8e-28 99.3 0.9 1.4 1 0 0 1 1 1 1 N-terminal domain of NWD NACHT-NTPase Ank PF00023.30 KXH49144.1 - 1.1e-26 92.1 18.7 0.072 13.6 0.1 15.0 16 0 0 16 16 16 5 Ankyrin repeat Methyltransf_32 PF13679.6 KXH49144.1 - 1e-22 80.8 0.1 2.9e-22 79.4 0.1 1.8 1 0 0 1 1 1 1 Methyltransferase domain Ank_5 PF13857.6 KXH49144.1 - 3.1e-22 78.3 12.3 0.0033 17.7 0.1 12.6 10 2 3 13 13 13 5 Ankyrin repeats (many copies) NACHT PF05729.12 KXH49144.1 - 7.9e-13 48.7 0.0 1.7e-12 47.6 0.0 1.5 1 0 0 1 1 1 1 NACHT domain Methyltransf_31 PF13847.6 KXH49144.1 - 6.4e-06 26.0 0.1 5.9e-05 22.9 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 KXH49144.1 - 0.00018 21.1 0.0 0.00039 20.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 KXH49144.1 - 0.00028 21.5 0.0 0.0072 17.0 0.0 3.2 2 0 0 2 2 2 1 Methyltransferase domain GidB PF02527.15 KXH49144.1 - 0.003 16.9 0.0 0.0059 15.9 0.0 1.4 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G Methyltransf_12 PF08242.12 KXH49144.1 - 0.053 14.3 0.3 0.22 12.3 0.0 2.2 2 0 0 2 2 1 0 Methyltransferase domain AAA_22 PF13401.6 KXH49144.1 - 0.074 13.3 0.0 0.22 11.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain PCMT PF01135.19 KXH49144.1 - 0.095 12.4 0.1 0.2 11.4 0.1 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) NB-ARC PF00931.22 KXH49144.1 - 0.13 11.5 0.0 0.27 10.4 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.22 KXH49144.1 - 0.19 12.1 0.0 0.37 11.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase MAGE_N PF12440.8 KXH49144.1 - 0.27 11.9 5.8 0.71 10.6 5.8 1.7 1 0 0 1 1 1 0 Melanoma associated antigen family N terminal PrmA PF06325.13 KXH49144.1 - 0.31 10.4 1.4 0.38 10.1 0.0 1.7 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Fungal_trans_2 PF11951.8 KXH49145.1 - 1.1e-10 41.0 3.7 7.2e-08 31.6 0.0 2.6 2 1 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH49145.1 - 7.5e-06 26.0 9.9 1.2e-05 25.4 9.9 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.22 KXH49146.1 - 1.8e-50 172.0 0.0 2.6e-50 171.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_10 PF00331.20 KXH49148.1 - 8.3e-100 334.0 0.0 9.8e-100 333.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_1 PF00734.18 KXH49148.1 - 7.8e-15 54.5 11.9 2.8e-14 52.8 11.9 2.1 1 0 0 1 1 1 1 Fungal cellulose binding domain Botulinum_HA-17 PF05588.11 KXH49148.1 - 1.4 9.1 4.2 6.6 6.8 0.5 2.3 1 1 0 2 2 2 0 Clostridium botulinum HA-17 domain ADH_zinc_N PF00107.26 KXH49149.1 - 8.5e-21 74.3 0.0 1.2e-20 73.8 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXH49149.1 - 3.3e-12 47.6 0.0 6.6e-12 46.6 0.0 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KXH49149.1 - 0.00018 20.9 0.0 0.00024 20.5 0.0 1.1 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 KXH49149.1 - 0.0003 20.2 0.1 0.00048 19.5 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_N PF08240.12 KXH49149.1 - 0.0052 16.7 0.1 0.011 15.6 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Peroxidase_2 PF01328.17 KXH49150.1 - 4.3e-42 144.8 0.0 5.5e-42 144.4 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 CFEM PF05730.11 KXH49151.1 - 1.9e-11 43.9 9.9 3.1e-11 43.2 9.9 1.3 1 0 0 1 1 1 1 CFEM domain GMC_oxred_C PF05199.13 KXH49152.1 - 9.4e-28 97.5 0.0 1.6e-27 96.8 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 KXH49152.1 - 1.6e-24 86.8 0.0 1.6e-22 80.2 0.0 2.8 2 1 0 2 2 2 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 KXH49152.1 - 0.00037 19.8 0.0 0.00083 18.7 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXH49152.1 - 0.0088 15.3 0.0 3.4 6.8 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXH49152.1 - 0.011 15.9 0.0 0.025 14.8 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KXH49152.1 - 0.019 14.1 0.0 0.026 13.6 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_2 PF00890.24 KXH49152.1 - 0.18 10.9 0.6 0.27 10.3 0.6 1.2 1 0 0 1 1 1 0 FAD binding domain Glyco_hydro_3_C PF01915.22 KXH49153.1 - 1.7e-49 168.6 0.0 2.6e-49 168.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KXH49153.1 - 1e-30 107.2 0.0 3.2e-30 105.6 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KXH49153.1 - 5.4e-24 84.1 0.1 1e-23 83.2 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain UbiA PF01040.18 KXH49155.1 - 4.3e-18 65.5 10.1 6.5e-18 64.9 10.1 1.4 1 0 0 1 1 1 1 UbiA prenyltransferase family Nuc_sug_transp PF04142.15 KXH49157.1 - 4.1e-09 36.0 5.9 1.1e-08 34.6 5.7 1.7 2 0 0 2 2 2 1 Nucleotide-sugar transporter NMN_transporter PF04973.12 KXH49157.1 - 0.0055 16.7 4.1 0.0055 16.7 4.1 1.7 2 0 0 2 2 2 1 Nicotinamide mononucleotide transporter ENOD93 PF03386.14 KXH49157.1 - 0.093 12.6 0.3 0.24 11.3 0.3 1.6 1 0 0 1 1 1 0 Early nodulin 93 ENOD93 protein Abhydrolase_3 PF07859.13 KXH49159.1 - 2.8e-40 138.5 0.0 4.3e-40 137.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KXH49159.1 - 2.4e-08 33.3 0.1 9.8e-08 31.3 0.1 1.7 1 1 0 1 1 1 1 Carboxylesterase family PHD PF00628.29 KXH49160.1 - 0.0064 16.4 8.1 0.015 15.2 3.0 2.2 2 0 0 2 2 2 1 PHD-finger DUF983 PF06170.12 KXH49160.1 - 0.025 15.0 3.6 1.2 9.6 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF983) C1_1 PF00130.22 KXH49160.1 - 0.046 13.6 11.2 1.7 8.6 11.2 2.2 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) ADK_lid PF05191.14 KXH49160.1 - 0.055 13.5 4.2 0.24 11.4 0.3 2.5 2 0 0 2 2 2 0 Adenylate kinase, active site lid Sgf11 PF08209.11 KXH49160.1 - 0.52 9.9 11.3 0.3 10.7 0.7 2.8 2 1 1 3 3 3 0 Sgf11 (transcriptional regulation protein) Lipase_GDSL_2 PF13472.6 KXH49161.1 - 2.9e-09 37.6 0.2 3.8e-09 37.2 0.2 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KXH49161.1 - 0.0046 17.0 0.0 0.0063 16.5 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DUF3818 PF12825.7 KXH49162.1 - 2.5e-57 194.5 0.1 6.1e-35 120.8 0.1 2.1 1 1 1 2 2 2 2 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 KXH49162.1 - 2.6e-41 140.7 0.1 4.4e-41 139.9 0.1 1.4 1 0 0 1 1 1 1 PX-associated Cation_efflux PF01545.21 KXH49163.1 - 8.3e-16 58.3 8.9 1e-15 58.0 8.9 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KXH49163.1 - 9.4e-09 35.3 1.3 2.1e-08 34.1 1.3 1.5 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter Pkinase PF00069.25 KXH49164.1 - 9.5e-22 77.6 0.0 3.2e-15 56.2 0.0 2.4 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXH49164.1 - 1.3e-14 54.1 0.0 2e-13 50.2 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 KXH49164.1 - 0.039 12.9 0.0 0.07 12.1 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase PAS_5 PF07310.13 KXH49165.1 - 0.17 11.7 0.0 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 PAS domain BAALC_N PF06989.12 KXH49166.1 - 0.013 15.8 2.7 0.041 14.2 2.7 1.8 1 0 0 1 1 1 0 BAALC N-terminus CorA PF01544.18 KXH49166.1 - 0.027 13.8 7.0 0.035 13.4 4.4 2.2 2 1 0 2 2 2 0 CorA-like Mg2+ transporter protein CX PF01705.19 KXH49166.1 - 0.035 14.6 0.0 0.11 13.0 0.0 1.9 2 0 0 2 2 2 0 CX module FliJ PF02050.16 KXH49166.1 - 2.8 8.2 4.9 0.83 9.9 1.3 1.9 2 0 0 2 2 2 0 Flagellar FliJ protein Goodbye PF17109.5 KXH49167.1 - 2.8e-15 56.8 0.4 1.4e-14 54.6 0.1 2.4 2 0 0 2 2 2 1 fungal STAND N-terminal Goodbye domain AAA_16 PF13191.6 KXH49167.1 - 0.00012 22.5 6.0 0.00039 20.9 0.0 4.4 5 0 0 5 5 5 1 AAA ATPase domain AAA_28 PF13521.6 KXH49167.1 - 0.00024 21.4 0.2 0.0036 17.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain TPR_2 PF07719.17 KXH49167.1 - 0.0004 20.3 9.0 0.043 13.9 0.4 5.6 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 KXH49167.1 - 0.00069 20.2 0.8 0.038 14.6 0.1 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat ATPase_2 PF01637.18 KXH49167.1 - 0.0019 18.2 0.0 0.0057 16.6 0.0 1.9 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea TPR_1 PF00515.28 KXH49167.1 - 0.0022 17.7 5.6 0.1 12.4 0.2 4.2 4 0 0 4 4 3 1 Tetratricopeptide repeat AAA_22 PF13401.6 KXH49167.1 - 0.0036 17.6 0.2 0.057 13.7 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_26 PF13500.6 KXH49167.1 - 0.0054 16.6 3.6 0.0074 16.1 0.0 3.0 4 0 0 4 4 4 1 AAA domain DUF3135 PF11333.8 KXH49167.1 - 0.012 15.8 0.5 0.12 12.6 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3135) EH_Signature PF15611.6 KXH49167.1 - 0.019 14.4 3.4 0.038 13.4 0.2 2.3 1 1 0 2 2 2 0 EH_Signature domain NACHT PF05729.12 KXH49167.1 - 0.039 13.9 0.0 0.15 11.9 0.0 2.1 2 0 0 2 2 2 0 NACHT domain TPR_4 PF07721.14 KXH49167.1 - 0.048 14.3 0.3 0.66 10.8 0.2 3.2 2 0 0 2 2 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 KXH49167.1 - 0.049 14.5 10.4 1e+02 4.1 0.1 6.8 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 KXH49167.1 - 0.11 12.8 6.7 0.45 10.9 0.3 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 KXH49167.1 - 0.11 13.0 2.7 0.22 12.0 0.3 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 KXH49167.1 - 0.14 12.3 2.2 55 4.1 0.2 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TniB PF05621.11 KXH49167.1 - 0.21 11.0 1.6 0.65 9.4 0.3 2.4 3 0 0 3 3 3 0 Bacterial TniB protein TPR_19 PF14559.6 KXH49167.1 - 1.5 9.4 15.6 0.18 12.3 0.4 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 KXH49167.1 - 2.4 8.5 13.3 0.032 14.5 1.0 4.1 5 0 0 5 5 4 0 Tetratricopeptide repeat Baculo_PEP_C PF04513.12 KXH49167.1 - 2.5 8.2 6.4 4.3 7.4 0.5 3.6 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus TPR_10 PF13374.6 KXH49167.1 - 2.7 8.0 9.3 0.83 9.6 0.4 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Glyco_hydro_53 PF07745.13 KXH49168.1 - 1.5e-81 274.1 0.1 1.7e-81 273.9 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 LysM PF01476.20 KXH49169.1 - 6.7e-07 29.3 2.5 3.6 7.7 0.1 4.8 5 0 0 5 5 5 4 LysM domain HSDR_N_2 PF13588.6 KXH49169.1 - 5.1e-05 23.2 0.0 0.014 15.4 0.0 2.4 2 0 0 2 2 2 2 Type I restriction enzyme R protein N terminus (HSDR_N) Slx4 PF09494.10 KXH49169.1 - 0.053 13.5 0.0 8.7 6.4 0.0 3.1 3 0 0 3 3 3 0 Slx4 endonuclease LysM PF01476.20 KXH49170.1 - 3e-12 46.4 0.6 1.5e-05 25.0 0.0 3.3 3 0 0 3 3 3 2 LysM domain Glyco_hydro_18 PF00704.28 KXH49171.1 - 2e-59 201.9 1.9 2.8e-59 201.4 1.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 KXH49171.1 - 3.8e-12 46.5 29.5 2.3e-10 40.8 5.5 4.4 5 0 0 5 5 5 2 Chitin recognition protein Glyco_hydro_85 PF03644.13 KXH49171.1 - 0.00027 20.4 0.2 0.00046 19.7 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 DUF4849 PF16141.5 KXH49171.1 - 0.17 11.1 0.1 0.29 10.4 0.1 1.2 1 0 0 1 1 1 0 Putative glycoside hydrolase Family 18, chitinase_18 Ank_2 PF12796.7 KXH49172.1 - 4.6e-30 104.1 0.0 8.3e-08 32.7 0.1 6.5 3 2 1 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXH49172.1 - 1.7e-28 98.6 0.2 9.8e-05 22.8 0.0 7.3 7 0 0 7 7 7 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXH49172.1 - 1.7e-19 69.6 4.6 0.00078 19.7 0.0 8.7 7 3 3 10 10 10 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXH49172.1 - 7.7e-17 59.7 3.7 0.47 11.2 0.0 10.4 12 1 0 12 12 12 5 Ankyrin repeat Ank PF00023.30 KXH49172.1 - 3.2e-16 59.0 7.7 0.86 10.2 0.0 10.3 9 1 1 10 10 10 5 Ankyrin repeat Dicty_REP PF05086.12 KXH49173.1 - 0.36 8.8 1.7 0.42 8.5 1.7 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein TFIIA PF03153.13 KXH49173.1 - 0.74 9.8 10.4 0.85 9.6 10.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Methyltransf_10 PF05971.12 KXH49212.1 - 0.16 11.3 0.0 0.29 10.4 0.0 1.4 1 0 0 1 1 1 0 RNA methyltransferase Fungal_trans PF04082.18 KXH49213.1 - 1.5e-23 83.2 0.1 3.4e-23 82.0 0.1 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH49213.1 - 1.6e-07 31.3 13.1 4e-07 30.0 13.1 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SUIM_assoc PF16619.5 KXH49213.1 - 0.17 12.0 4.4 0.06 13.4 0.8 2.1 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 CALCOCO1 PF07888.11 KXH49215.1 - 0.0044 15.9 12.9 0.0049 15.8 12.9 1.0 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like FlaC_arch PF05377.11 KXH49215.1 - 0.011 16.1 3.6 0.019 15.3 2.7 1.9 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Tup_N PF08581.10 KXH49215.1 - 0.031 14.6 0.9 0.061 13.6 0.9 1.6 1 0 0 1 1 1 0 Tup N-terminal EMP24_GP25L PF01105.24 KXH49215.1 - 0.034 14.1 4.6 0.066 13.1 4.6 1.7 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD THOC7 PF05615.13 KXH49215.1 - 0.068 13.4 6.7 0.12 12.7 6.4 1.7 1 1 0 1 1 1 0 Tho complex subunit 7 DUF1664 PF07889.12 KXH49215.1 - 0.11 12.5 4.9 0.077 13.0 1.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) COG2 PF06148.11 KXH49215.1 - 0.46 10.6 6.3 0.075 13.1 2.1 1.8 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Fez1 PF06818.15 KXH49215.1 - 0.78 10.2 12.2 0.61 10.5 3.0 2.0 1 1 1 2 2 2 0 Fez1 DUF948 PF06103.11 KXH49215.1 - 0.87 9.9 9.0 5.1 7.4 9.0 2.3 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Spc7 PF08317.11 KXH49215.1 - 1.1 8.0 11.9 0.67 8.8 6.6 1.9 1 1 1 2 2 2 0 Spc7 kinetochore protein Atg14 PF10186.9 KXH49215.1 - 1.5 7.8 9.6 4.5 6.3 2.3 2.0 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 PTR2 PF00854.21 KXH49224.1 - 2e-77 260.7 4.5 2.6e-77 260.3 4.5 1.2 1 0 0 1 1 1 1 POT family Holin_SPP1 PF04688.13 KXH49224.1 - 0.087 13.0 0.3 0.32 11.2 0.3 1.9 1 0 0 1 1 1 0 SPP1 phage holin Sugar_tr PF00083.24 KXH49224.1 - 0.14 11.0 18.6 0.064 12.1 0.5 3.2 3 0 0 3 3 3 0 Sugar (and other) transporter ERG2_Sigma1R PF04622.12 KXH49225.1 - 5.5e-91 303.6 0.8 6.4e-63 211.9 0.1 2.0 2 0 0 2 2 2 2 ERG2 and Sigma1 receptor like protein UCR_6-4kD PF08997.10 KXH49225.1 - 0.13 12.2 0.2 2.7 8.0 0.0 2.8 3 0 0 3 3 3 0 Ubiquinol-cytochrome C reductase complex, 6.4kD protein EXOSC1 PF10447.9 KXH49226.1 - 1.8e-19 70.4 2.1 4.9e-14 52.9 0.2 2.5 1 1 1 2 2 2 2 Exosome component EXOSC1/CSL4 ECR1_N PF14382.6 KXH49226.1 - 1.8e-10 40.4 1.8 2.1e-10 40.2 0.7 1.7 2 0 0 2 2 2 1 Exosome complex exonuclease RRP4 N-terminal region MotA_activ PF09114.10 KXH49226.1 - 0.098 12.8 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Transcription factor MotA, activation domain Sec2p PF06428.11 KXH49227.1 - 9.2e-12 44.8 6.1 9.2e-12 44.8 6.1 1.8 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p SlyX PF04102.12 KXH49227.1 - 0.017 15.7 11.3 0.56 10.9 3.1 3.2 2 1 1 3 3 3 0 SlyX TF_Zn_Ribbon PF08271.12 KXH49227.1 - 0.11 12.0 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 TFIIB zinc-binding MbeD_MobD PF04899.12 KXH49227.1 - 0.17 12.0 7.5 0.77 9.9 0.6 3.2 2 1 1 3 3 3 0 MbeD/MobD like BST2 PF16716.5 KXH49227.1 - 0.54 10.9 8.8 2 9.0 5.1 2.6 3 0 0 3 3 3 0 Bone marrow stromal antigen 2 HAUS-augmin3 PF14932.6 KXH49227.1 - 0.75 9.3 10.7 0.24 11.0 7.1 1.9 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 Lzipper-MIP1 PF14389.6 KXH49227.1 - 0.97 9.8 8.1 23 5.4 5.3 3.2 2 1 1 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 Jnk-SapK_ap_N PF09744.9 KXH49227.1 - 1.1 9.4 11.6 7 6.8 8.9 2.2 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Exonuc_VII_L PF02601.15 KXH49227.1 - 2.2 7.8 8.5 4 6.9 8.5 1.6 1 1 0 1 1 1 0 Exonuclease VII, large subunit DUF5446 PF17522.2 KXH49227.1 - 3.4 7.9 7.2 10 6.3 0.2 2.9 1 1 2 3 3 3 0 Family of unknown function (DUF5446) FliT PF05400.13 KXH49227.1 - 3.5 8.5 18.4 1.1 10.1 0.1 3.3 3 1 0 3 3 3 0 Flagellar protein FliT DUF4407 PF14362.6 KXH49227.1 - 7.3 5.8 8.9 79 2.5 8.9 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) TruB_N PF01509.18 KXH49228.1 - 1.2e-44 152.3 0.0 3.2e-44 150.9 0.0 1.7 1 0 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 KXH49228.1 - 9.3e-05 22.5 0.0 0.00019 21.5 0.0 1.5 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain DNMT1-RFD PF12047.8 KXH49229.1 - 0.00027 21.0 0.0 0.00054 20.0 0.0 1.5 1 0 0 1 1 1 1 Cytosine specific DNA methyltransferase replication foci domain MKT1_C PF12246.8 KXH49230.1 - 3.2e-73 245.9 0.1 4.8e-73 245.3 0.1 1.3 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.8 KXH49230.1 - 3e-31 107.6 0.0 6e-31 106.6 0.0 1.5 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_N PF00752.17 KXH49230.1 - 0.00082 19.8 0.0 0.003 18.0 0.0 1.9 1 0 0 1 1 1 1 XPG N-terminal domain DIOX_N PF14226.6 KXH49232.1 - 2.7e-22 79.7 0.0 4.2e-22 79.1 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KXH49232.1 - 1e-13 51.6 0.0 2.2e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DNA_ligase_A_M PF01068.21 KXH49233.1 - 1e-23 84.1 0.1 1.8e-23 83.3 0.1 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KXH49233.1 - 3e-21 76.5 0.0 1e-20 74.8 0.0 1.8 2 0 0 2 2 2 1 DNA ligase N terminus RNA_ligase PF09414.10 KXH49233.1 - 3.1e-06 27.6 0.0 6.6e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 RNA ligase DUF4048 PF13257.6 KXH49234.1 - 1.1e-13 51.7 5.5 1.1e-13 51.7 5.5 4.8 4 1 2 6 6 6 3 Domain of unknown function (DUF4048) Iso_dh PF00180.20 KXH49235.1 - 6.2e-118 393.9 0.0 1.1e-117 393.2 0.0 1.4 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase ATP-synt_ab PF00006.25 KXH49235.1 - 1.6e-108 361.3 0.0 2.5e-108 360.6 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 KXH49235.1 - 6.9e-47 158.3 0.0 1.5e-46 157.2 0.0 1.6 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 KXH49235.1 - 6.4e-15 55.4 2.8 1.6e-14 54.1 2.8 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain LPD23 PF18838.1 KXH49235.1 - 0.16 11.8 0.1 0.37 10.6 0.1 1.6 1 0 0 1 1 1 0 Large polyvalent protein associated domain 23 DUF4061 PF13270.6 KXH49235.1 - 0.23 11.8 0.6 0.52 10.7 0.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4061) DUF2264 PF10022.9 KXH49236.1 - 3.4e-134 447.4 0.4 4.4e-134 447.0 0.4 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) FH2 PF02181.23 KXH49237.1 - 3.2e-86 289.8 5.7 4.4e-86 289.3 5.7 1.1 1 0 0 1 1 1 1 Formin Homology 2 Domain Methyltransf_5 PF01795.19 KXH49237.1 - 0.00094 18.8 1.9 0.0015 18.1 1.9 1.2 1 0 0 1 1 1 1 MraW methylase family CBM_21 PF03370.13 KXH49265.1 - 1.7e-35 121.6 0.8 2.8e-35 120.9 0.8 1.3 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 KXH49265.1 - 8.7e-11 42.3 1.5 2e-10 41.1 1.5 1.6 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) AAA PF00004.29 KXH49268.1 - 1.2e-16 61.3 0.0 4.7e-16 59.4 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KXH49268.1 - 0.00045 20.6 0.4 0.0025 18.2 0.4 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KXH49268.1 - 0.00092 19.5 1.9 0.016 15.5 0.7 3.0 2 1 0 2 2 2 1 AAA domain ATPase PF06745.13 KXH49268.1 - 0.0086 15.4 0.4 0.019 14.3 0.4 1.6 1 0 0 1 1 1 1 KaiC DnaB_C PF03796.15 KXH49268.1 - 0.051 12.9 0.3 0.19 11.0 0.0 2.0 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain AAA_33 PF13671.6 KXH49268.1 - 0.06 13.5 0.0 0.34 11.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 KXH49268.1 - 0.077 13.0 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 KXH49268.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_30 PF13604.6 KXH49268.1 - 0.12 12.1 0.2 0.34 10.6 0.2 1.7 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KXH49268.1 - 0.14 11.5 0.3 0.33 10.3 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI CEP209_CC5 PF16574.5 KXH49269.1 - 0.2 11.8 4.4 0.89 9.7 1.8 2.7 2 1 1 3 3 3 0 Coiled-coil region of centrosome protein CE290 MutS_III PF05192.18 KXH49269.1 - 0.58 10.3 2.4 1.6 8.9 2.5 1.7 1 1 0 1 1 1 0 MutS domain III DHHC PF01529.20 KXH49270.1 - 8.6e-35 119.8 14.5 8.6e-35 119.8 14.5 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase Ank_2 PF12796.7 KXH49270.1 - 8.1e-29 100.1 0.0 1.4e-13 51.3 0.0 3.1 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXH49270.1 - 1.2e-24 86.3 2.7 3.8e-06 27.3 0.0 5.0 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 KXH49270.1 - 5.4e-23 80.4 0.4 6.6e-05 23.2 0.0 5.6 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 KXH49270.1 - 6.5e-23 78.3 0.5 3.4e-07 30.1 0.0 6.1 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 KXH49270.1 - 2e-22 79.0 0.2 2.8e-06 27.5 0.0 5.7 3 2 2 5 5 5 4 Ankyrin repeats (many copies) SRPRB PF09439.10 KXH49271.1 - 1.4e-26 93.1 0.0 3.4e-26 91.8 0.0 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KXH49271.1 - 6.4e-05 23.0 0.0 0.0001 22.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 KXH49271.1 - 0.00066 20.0 0.0 0.002 18.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KXH49271.1 - 0.00077 19.9 0.2 0.0013 19.2 0.2 1.6 1 1 0 1 1 1 1 AAA ATPase domain Arf PF00025.21 KXH49271.1 - 0.0014 18.2 0.0 0.95 8.9 0.0 2.6 2 2 0 2 2 2 2 ADP-ribosylation factor family Septin PF00735.18 KXH49271.1 - 0.0025 17.1 0.0 0.0055 16.0 0.0 1.5 2 0 0 2 2 2 1 Septin Roc PF08477.13 KXH49271.1 - 0.025 14.8 0.0 0.069 13.4 0.0 1.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 KXH49271.1 - 0.027 13.9 0.0 0.045 13.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein RsgA_GTPase PF03193.16 KXH49271.1 - 0.075 12.9 0.3 0.28 11.1 0.3 2.0 2 1 0 2 2 2 0 RsgA GTPase ABC_tran PF00005.27 KXH49271.1 - 0.083 13.4 0.0 0.13 12.8 0.0 1.3 1 0 0 1 1 1 0 ABC transporter GTP_EFTU PF00009.27 KXH49271.1 - 0.12 11.9 0.0 0.88 9.1 0.0 2.1 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA PF00004.29 KXH49271.1 - 0.14 12.6 0.3 1.9 8.9 0.3 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 KXH49271.1 - 0.16 11.7 0.2 0.23 11.1 0.2 1.3 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 KXH49271.1 - 0.18 11.4 0.2 4.3 6.9 0.3 2.2 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PALP PF00291.25 KXH49272.1 - 1.6e-66 224.7 0.1 2.1e-66 224.3 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.28 KXH49272.1 - 3.1e-12 46.7 0.0 4e-09 36.8 0.0 2.9 2 0 0 2 2 2 2 CBS domain Pyr_redox_2 PF07992.14 KXH49273.1 - 2e-30 106.0 0.0 2.6e-30 105.7 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXH49273.1 - 4e-10 40.1 0.3 3.2e-08 34.0 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXH49273.1 - 4.2e-06 26.6 1.1 1.9 8.0 0.1 4.0 4 0 0 4 4 4 3 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KXH49273.1 - 7e-06 25.5 0.0 1e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXH49273.1 - 0.0016 18.5 2.3 3.4 7.6 0.1 3.9 2 2 2 4 4 4 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 KXH49273.1 - 0.0025 17.0 0.0 0.0062 15.7 0.0 1.6 1 1 1 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.14 KXH49273.1 - 0.0054 15.6 0.1 1.5 7.6 0.0 2.5 2 0 0 2 2 2 2 Tryptophan halogenase Thi4 PF01946.17 KXH49273.1 - 0.0066 15.7 1.0 11 5.1 0.0 3.4 4 0 0 4 4 4 1 Thi4 family NAD_binding_8 PF13450.6 KXH49273.1 - 0.15 12.3 0.7 18 5.6 0.1 2.7 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 KXH49273.1 - 0.16 11.0 5.6 3.3 6.7 0.0 2.4 3 0 0 3 3 3 0 Glucose inhibited division protein A Abhydrolase_1 PF00561.20 KXH49273.1 - 0.17 11.5 0.0 0.94 9.1 0.0 1.9 2 0 0 2 2 2 0 alpha/beta hydrolase fold FAD_binding_3 PF01494.19 KXH49273.1 - 0.35 10.1 1.8 0.59 9.3 0.1 2.0 2 0 0 2 2 2 0 FAD binding domain Lycopene_cycl PF05834.12 KXH49273.1 - 0.37 9.8 2.1 1.4 7.9 0.1 2.8 3 1 1 4 4 4 0 Lycopene cyclase protein FAD_oxidored PF12831.7 KXH49273.1 - 0.92 8.8 4.3 6.5 6.0 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase AAA PF00004.29 KXH49278.1 - 5.3e-17 62.5 0.0 1.2e-16 61.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KXH49278.1 - 0.00029 21.3 0.0 0.0011 19.4 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KXH49278.1 - 0.012 15.9 0.0 0.047 14.0 0.0 2.0 1 1 0 1 1 1 0 AAA domain RuvB_N PF05496.12 KXH49278.1 - 0.015 15.1 0.0 0.027 14.2 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KXH49278.1 - 0.022 14.8 0.0 0.06 13.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 KXH49278.1 - 0.1 13.1 0.0 0.46 11.0 0.0 2.2 1 0 0 1 1 1 0 AAA domain FAD_binding_4 PF01565.23 KXH49279.1 - 7.4e-21 74.3 0.1 1.1e-20 73.8 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pro-kuma_activ PF09286.11 KXH49280.1 - 4.9e-27 95.0 0.0 1.7e-26 93.2 0.0 1.9 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KXH49280.1 - 0.0008 18.8 0.4 0.0014 18.0 0.4 1.4 1 0 0 1 1 1 1 Subtilase family DUF2985 PF11204.8 KXH49281.1 - 1.4e-37 127.7 0.6 1.4e-37 127.7 0.6 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2985) ICMT PF04140.14 KXH49282.1 - 3e-08 34.0 0.2 2.3e-07 31.1 0.0 2.2 1 1 1 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KXH49282.1 - 5.9e-08 33.1 0.2 1.1e-06 28.9 0.1 2.3 1 1 1 2 2 2 1 Phospholipid methyltransferase Sugar_tr PF00083.24 KXH49283.1 - 4.7e-62 210.3 33.2 5.8e-62 210.0 33.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH49283.1 - 3.3e-21 75.6 30.9 6.1e-21 74.7 31.0 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Glyco_hyd_65N_2 PF14498.6 KXH49284.1 - 1.2e-59 202.0 0.0 1.6e-59 201.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain NUDE_C PF04880.13 KXH49285.1 - 1.1e-38 133.4 18.5 1.1e-38 133.4 18.5 5.0 2 2 2 4 4 1 1 NUDE protein, C-terminal conserved region ZapB PF06005.12 KXH49285.1 - 0.00077 19.8 9.0 0.00077 19.8 9.0 4.8 2 1 3 5 5 5 1 Cell division protein ZapB Alanine_zipper PF11839.8 KXH49285.1 - 0.0043 17.4 7.3 0.0043 17.4 7.3 2.5 3 0 0 3 3 2 1 Alanine-zipper, major outer membrane lipoprotein PSII_Pbs27 PF13326.6 KXH49285.1 - 0.0083 16.5 4.5 0.0083 16.5 4.5 1.8 2 0 0 2 2 2 1 Photosystem II Pbs27 Chibby PF14645.6 KXH49285.1 - 0.092 13.1 16.1 0.3 11.5 8.0 2.6 1 1 1 2 2 2 0 Chibby family FPP PF05911.11 KXH49285.1 - 0.12 10.5 34.9 0.0077 14.5 18.9 2.1 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil DUF3584 PF12128.8 KXH49285.1 - 0.15 9.5 27.0 0.22 9.0 27.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) CENP-F_leu_zip PF10473.9 KXH49285.1 - 0.16 12.0 39.9 19 5.2 32.9 3.9 2 1 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 YjbH PF06082.11 KXH49285.1 - 0.28 10.0 8.7 0.43 9.3 8.7 1.2 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH Fez1 PF06818.15 KXH49285.1 - 0.28 11.6 32.6 0.096 13.1 15.1 2.8 2 1 1 3 3 3 0 Fez1 AKNA PF12443.8 KXH49285.1 - 0.63 10.7 9.2 6.2 7.6 4.0 3.3 3 0 0 3 3 3 0 AT-hook-containing transcription factor ERM PF00769.19 KXH49285.1 - 0.77 9.5 39.3 0.21 11.3 20.5 2.3 1 1 1 2 2 2 0 Ezrin/radixin/moesin family IFT57 PF10498.9 KXH49285.1 - 0.92 8.4 27.9 0.077 11.9 13.3 2.1 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 Tropomyosin_1 PF12718.7 KXH49285.1 - 0.96 9.6 41.6 25 5.0 26.5 4.4 2 1 1 3 3 3 0 Tropomyosin like Tho2 PF11262.8 KXH49285.1 - 1.7 7.8 21.4 0.29 10.3 3.7 2.1 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 Filament PF00038.21 KXH49285.1 - 1.8 8.1 36.2 1.6 8.3 10.9 2.4 2 1 1 3 3 3 0 Intermediate filament protein Prefoldin_2 PF01920.20 KXH49285.1 - 2.9 7.9 35.8 0.54 10.2 11.1 5.2 2 1 3 5 5 4 0 Prefoldin subunit Atg14 PF10186.9 KXH49285.1 - 7.1 5.6 30.8 3.2 6.7 14.2 3.0 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 ATG16 PF08614.11 KXH49285.1 - 7.7 6.7 42.1 0.023 14.9 19.0 3.2 2 2 2 4 4 4 0 Autophagy protein 16 (ATG16) ACC_central PF08326.12 KXH49287.1 - 1.3e-276 919.6 0.0 1.6e-276 919.3 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.22 KXH49287.1 - 8.9e-183 608.4 0.0 1.2e-182 608.0 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 KXH49287.1 - 8.8e-51 172.4 0.0 1.6e-50 171.5 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 KXH49287.1 - 1.2e-27 96.6 0.1 2.7e-27 95.5 0.1 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KXH49287.1 - 6.5e-22 77.7 0.0 3.4e-20 72.1 0.0 2.9 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 KXH49287.1 - 2.8e-17 62.3 0.1 6e-17 61.2 0.1 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme GxGYxYP_N PF16216.5 KXH49287.1 - 0.0018 18.5 0.1 0.0056 16.9 0.1 1.8 1 0 0 1 1 1 1 GxGYxY sequence motif in domain of unknown function N-terminal Biotin_lipoyl_2 PF13533.6 KXH49287.1 - 0.0024 17.7 0.0 0.0077 16.0 0.0 1.8 1 0 0 1 1 1 1 Biotin-lipoyl like RnfC_N PF13375.6 KXH49287.1 - 0.044 13.7 0.0 0.15 12.0 0.0 1.9 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain ATP-grasp_3 PF02655.14 KXH49287.1 - 0.09 12.8 0.0 0.49 10.4 0.0 2.3 2 0 0 2 2 2 0 ATP-grasp domain Dala_Dala_lig_C PF07478.13 KXH49287.1 - 0.1 12.1 0.0 0.37 10.3 0.0 2.0 2 0 0 2 2 2 0 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 KXH49287.1 - 0.16 11.7 0.0 0.35 10.6 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon Glyco_hydro_43 PF04616.14 KXH49289.1 - 1.8e-72 244.1 0.2 2.9e-72 243.4 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Abhydrolase_1 PF00561.20 KXH49289.1 - 5.5e-17 62.3 0.1 8.2e-15 55.1 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXH49289.1 - 2e-15 58.0 2.6 3.7e-14 53.9 2.6 2.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family GH43_C2 PF17851.1 KXH49289.1 - 3.9e-14 52.9 0.0 6.9e-14 52.0 0.0 1.4 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain Hydrolase_4 PF12146.8 KXH49289.1 - 5.9e-10 38.8 0.0 1.1e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Chlorophyllase PF07224.11 KXH49289.1 - 0.068 12.2 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Chlorophyllase2 PF12740.7 KXH49289.1 - 0.17 10.8 0.0 0.33 9.8 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase enzyme Fungal_trans PF04082.18 KXH49290.1 - 2e-07 30.3 0.3 7.9e-07 28.4 0.3 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain SQHop_cyclase_C PF13243.6 KXH49290.1 - 0.046 12.8 0.0 0.067 12.3 0.0 1.2 1 0 0 1 1 1 0 Squalene-hopene cyclase C-terminal domain ANAPC5 PF12862.7 KXH49290.1 - 0.13 12.4 0.1 0.32 11.1 0.1 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 5 Sugar_tr PF00083.24 KXH49291.1 - 5.3e-84 282.7 21.9 6.1e-84 282.5 21.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH49291.1 - 1.1e-18 67.3 36.6 2.7e-18 66.0 33.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 KXH49291.1 - 0.035 12.5 4.3 0.056 11.8 0.2 2.3 2 1 0 2 2 2 0 Transmembrane secretion effector TRI12 PF06609.13 KXH49291.1 - 0.071 11.5 7.3 0.016 13.6 2.3 1.9 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) MttA_Hcf106 PF02416.16 KXH49291.1 - 0.46 9.8 3.7 3.8 6.9 0.3 3.3 3 0 0 3 3 3 0 mttA/Hcf106 family MFS_1_like PF12832.7 KXH49291.1 - 2.8 6.7 12.1 0.12 11.2 2.3 2.8 2 1 1 3 3 3 0 MFS_1 like family DUF417 PF04224.12 KXH49291.1 - 8.6 5.9 9.6 0.16 11.5 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function, DUF417 PI-PLC-X PF00388.19 KXH49292.1 - 3.4e-62 208.3 0.0 5.3e-62 207.7 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 KXH49292.1 - 5.4e-42 142.8 0.0 8.5e-42 142.1 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain FMO-like PF00743.19 KXH49293.1 - 7.7e-26 90.6 0.0 1.1e-11 43.9 0.0 3.1 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KXH49293.1 - 3.4e-10 39.7 0.2 1e-07 31.6 0.1 3.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXH49293.1 - 1.5e-07 31.0 0.0 5.6e-06 25.8 0.0 2.5 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXH49293.1 - 1.6e-07 30.8 0.8 0.0014 17.8 0.0 3.2 3 1 1 4 4 4 3 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KXH49293.1 - 3.4e-06 27.1 0.4 0.0011 19.0 0.0 3.1 3 1 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KXH49293.1 - 0.00013 22.1 0.0 0.00035 20.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Glu_dehyd_C PF16912.5 KXH49293.1 - 0.044 13.3 0.0 0.083 12.4 0.0 1.4 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus DAO PF01266.24 KXH49293.1 - 0.08 12.5 0.1 1.3 8.6 0.0 2.5 3 0 0 3 3 3 0 FAD dependent oxidoreductase DUF498 PF04430.14 KXH49293.1 - 0.12 12.4 0.0 3.3 7.8 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF498/DUF598) Thi4 PF01946.17 KXH49293.1 - 0.14 11.4 0.1 0.88 8.8 0.0 2.0 2 0 0 2 2 2 0 Thi4 family DUF3473 PF11959.8 KXH49293.1 - 0.17 12.0 0.5 1.3 9.1 0.5 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3473) HI0933_like PF03486.14 KXH49293.1 - 0.25 10.0 0.0 0.52 9.0 0.0 1.5 1 0 0 1 1 1 0 HI0933-like protein Cu-oxidase_2 PF07731.14 KXH49323.1 - 9.4e-48 161.4 10.1 1e-44 151.6 0.3 3.3 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 KXH49323.1 - 2.3e-42 143.8 3.1 2.3e-42 143.8 3.1 2.4 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.22 KXH49323.1 - 4.2e-35 121.2 0.0 1.7e-34 119.3 0.0 2.0 2 0 0 2 2 2 1 Multicopper oxidase Cupin_2 PF07883.11 KXH49324.1 - 2.2e-06 27.3 0.0 3.5e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Cupin domain NACHT PF05729.12 KXH49325.1 - 1.1e-11 45.0 1.2 5.8e-11 42.6 0.1 2.2 2 0 0 2 2 2 1 NACHT domain Helo_like_N PF17111.5 KXH49325.1 - 1.3e-08 34.4 0.7 3.9e-08 32.9 0.7 1.9 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins SesA PF17107.5 KXH49325.1 - 8.7e-08 32.4 3.5 5e-07 29.9 0.5 3.2 3 1 0 3 3 3 1 N-terminal domain on NACHT_NTPase and P-loop NTPases AAA_22 PF13401.6 KXH49325.1 - 3.1e-05 24.2 2.9 0.00035 20.9 0.0 3.0 3 1 0 3 3 3 1 AAA domain NB-ARC PF00931.22 KXH49325.1 - 0.00085 18.6 0.2 0.0034 16.6 0.0 2.1 2 1 0 2 2 2 1 NB-ARC domain AAA_16 PF13191.6 KXH49325.1 - 0.00087 19.7 3.6 0.0013 19.1 0.2 2.4 2 0 0 2 2 2 1 AAA ATPase domain AIP3 PF03915.13 KXH49325.1 - 0.012 14.7 0.2 0.03 13.4 0.2 1.6 1 0 0 1 1 1 0 Actin interacting protein 3 Syntaxin PF00804.25 KXH49325.1 - 0.015 15.0 0.5 0.055 13.1 0.5 2.0 2 0 0 2 2 2 0 Syntaxin Phage_HK97_TLTM PF06120.11 KXH49325.1 - 0.026 13.7 0.1 0.041 13.1 0.1 1.3 1 0 0 1 1 1 0 Tail length tape measure protein DUF2383 PF09537.10 KXH49325.1 - 0.033 14.5 0.1 0.13 12.6 0.1 2.1 2 1 0 2 2 1 0 Domain of unknown function (DUF2383) DLP_helical PF18709.1 KXH49325.1 - 0.055 12.7 0.1 0.12 11.6 0.1 1.6 1 0 0 1 1 1 0 Dynamin-like helical domain V-SNARE PF05008.15 KXH49325.1 - 0.14 12.5 5.4 0.082 13.3 0.9 2.9 2 1 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus HrcA PF01628.21 KXH49325.1 - 0.15 11.9 3.6 0.097 12.6 1.3 1.8 2 0 0 2 2 2 0 HrcA protein C terminal domain V-ATPase_G_2 PF16999.5 KXH49325.1 - 0.16 12.4 1.5 0.4 11.1 1.5 1.6 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit MutS_III PF05192.18 KXH49325.1 - 0.17 12.1 8.6 1.5 9.0 8.5 2.5 1 1 0 1 1 1 0 MutS domain III FapA PF03961.13 KXH49325.1 - 0.2 10.2 0.3 0.39 9.3 0.3 1.4 1 0 0 1 1 1 0 Flagellar Assembly Protein A Syntaxin-6_N PF09177.11 KXH49325.1 - 0.29 11.7 2.6 0.33 11.5 0.4 2.4 2 0 0 2 2 1 0 Syntaxin 6, N-terminal CorA PF01544.18 KXH49325.1 - 0.52 9.6 4.3 1.6 7.9 4.3 1.9 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF3405 PF11885.8 KXH49327.1 - 5.5e-194 645.6 0.9 5.5e-194 645.6 0.9 1.9 2 1 0 2 2 2 1 Protein of unknown function (DUF3405) LIM PF00412.22 KXH49328.1 - 5e-21 74.7 16.5 2.5e-11 43.6 3.1 2.6 3 0 0 3 3 3 2 LIM domain zf-C2H2 PF00096.26 KXH49328.1 - 0.21 12.1 3.5 18 6.0 0.1 3.3 2 0 0 2 2 2 0 Zinc finger, C2H2 type Abhydrolase_6 PF12697.7 KXH49330.1 - 1.3e-05 25.9 11.0 2.9e-05 24.8 11.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ureidogly_lyase PF04115.12 KXH49331.1 - 9.2e-59 198.3 0.0 1.2e-58 198.0 0.0 1.0 1 0 0 1 1 1 1 Ureidoglycolate lyase SNF2_N PF00176.23 KXH49332.1 - 3e-21 75.5 0.4 3.2e-20 72.1 0.4 2.1 1 1 0 1 1 1 1 SNF2 family N-terminal domain zf-RING_5 PF14634.6 KXH49332.1 - 4.6e-05 23.3 6.1 9.7e-05 22.2 6.1 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KXH49332.1 - 0.00051 19.9 1.7 0.0012 18.6 1.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.15 KXH49332.1 - 0.0012 18.9 0.0 0.0027 17.7 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4_2 PF13923.6 KXH49332.1 - 0.0029 17.4 3.9 0.0071 16.2 3.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXH49332.1 - 0.012 15.9 5.6 0.027 14.8 5.6 1.6 1 0 0 1 1 1 0 Ring finger domain zf-RING_UBOX PF13445.6 KXH49332.1 - 0.16 12.0 3.5 0.38 10.8 3.5 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_5 PF17121.5 KXH49332.1 - 0.16 11.8 5.0 0.52 10.2 5.0 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 KXH49332.1 - 0.18 11.6 5.7 0.47 10.3 5.7 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-UDP PF14569.6 KXH49332.1 - 0.27 11.4 2.7 0.65 10.2 2.7 1.5 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-C3HC4_4 PF15227.6 KXH49332.1 - 0.33 11.1 1.4 0.96 9.7 1.4 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_10 PF16685.5 KXH49332.1 - 0.47 10.6 2.6 1.2 9.3 2.6 1.7 1 0 0 1 1 1 0 zinc RING finger of MSL2 Prok-RING_4 PF14447.6 KXH49332.1 - 1.7 8.5 5.9 3.8 7.5 5.9 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 DNA_methylase PF00145.17 KXH49333.1 - 2.4e-12 46.9 0.0 3.4e-09 36.5 0.0 2.3 2 0 0 2 2 2 2 C-5 cytosine-specific DNA methylase PHM7_ext PF12621.8 KXH49334.1 - 0.56 10.4 0.0 0.56 10.4 0.0 2.4 3 0 0 3 3 3 0 Extracellular tail, of 10TM putative phosphate transporter Ribosomal_L44 PF00935.19 KXH49335.1 - 2.7e-36 123.9 12.2 4.1e-36 123.3 12.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 DUF3405 PF11885.8 KXH49336.1 - 1.1e-206 687.5 0.1 1.4e-206 687.1 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) TcpQ PF10671.9 KXH49336.1 - 0.001 19.2 0.1 0.0032 17.5 0.1 1.8 1 0 0 1 1 1 1 Toxin co-regulated pilus biosynthesis protein Q K_oxygenase PF13434.6 KXH49337.1 - 6.8e-16 58.3 0.0 2.6e-11 43.3 0.0 2.2 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KXH49337.1 - 1.9e-11 43.8 0.0 0.0004 19.7 0.0 3.6 3 1 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXH49337.1 - 2.1e-07 30.5 0.0 0.0018 17.6 0.1 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXH49337.1 - 5.6e-05 22.9 1.3 0.033 13.8 0.4 3.5 3 1 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KXH49337.1 - 0.00025 20.4 0.0 0.022 14.0 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.6 KXH49337.1 - 0.00036 20.6 0.0 0.069 13.1 0.0 2.6 2 0 0 2 2 2 1 FAD-NAD(P)-binding HI0933_like PF03486.14 KXH49337.1 - 0.0076 15.0 0.0 0.67 8.6 0.0 2.3 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 KXH49337.1 - 0.0099 16.4 0.0 33 5.1 0.0 3.6 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KXH49337.1 - 0.033 13.3 0.0 0.065 12.3 0.0 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.17 KXH49337.1 - 0.054 12.7 0.0 0.094 11.9 0.0 1.4 1 0 0 1 1 1 0 Thi4 family NAD_binding_8 PF13450.6 KXH49337.1 - 0.095 12.9 0.2 0.62 10.3 0.0 2.3 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.20 KXH49337.1 - 0.19 11.8 0.0 16 5.6 0.0 2.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase CTP_transf_like PF01467.26 KXH49339.1 - 3.8e-20 72.5 0.0 6.7e-20 71.7 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase-like Fungal_trans PF04082.18 KXH49341.1 - 7e-16 58.0 0.0 1.9e-15 56.6 0.0 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KXH49341.1 - 9.9e-07 28.9 11.0 0.005 17.2 0.7 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXH49341.1 - 0.0048 17.6 8.1 0.61 11.1 2.2 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger AMPK1_CBM PF16561.5 KXH49342.1 - 9.1e-17 61.1 0.4 8.4e-10 38.7 0.1 2.4 2 0 0 2 2 2 2 Glycogen recognition site of AMP-activated protein kinase PTS_IIA PF02255.16 KXH49342.1 - 0.38 10.8 6.1 1.2 9.3 6.1 1.8 1 0 0 1 1 1 0 PTS system, Lactose/Cellobiose specific IIA subunit zf-C3HC4 PF00097.25 KXH49343.1 - 6.6e-08 32.3 6.1 1.1e-07 31.6 6.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXH49343.1 - 1.5e-06 28.2 6.3 3.3e-06 27.0 6.3 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KXH49343.1 - 1.8e-06 27.7 4.1 3.5e-06 26.8 4.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXH49343.1 - 4.2e-06 27.0 6.5 7.4e-06 26.2 6.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KXH49343.1 - 1.2e-05 25.2 4.0 2.2e-05 24.3 4.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KXH49343.1 - 1.2e-05 25.3 3.3 2.8e-05 24.2 3.3 1.6 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 KXH49343.1 - 1.3e-05 24.9 5.0 1.9e-05 24.4 1.9 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KXH49343.1 - 0.0035 17.2 7.2 0.016 15.0 7.1 2.1 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 KXH49343.1 - 0.094 13.0 3.5 0.23 11.7 3.5 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain TerY_C PF15616.6 KXH49343.1 - 0.51 10.5 1.8 0.64 10.1 0.4 1.8 2 0 0 2 2 2 0 TerY-C metal binding domain zf-MIZ PF02891.20 KXH49343.1 - 0.66 9.8 5.3 2.5 7.9 5.0 2.1 1 1 1 2 2 2 0 MIZ/SP-RING zinc finger zf-RING_10 PF16685.5 KXH49343.1 - 0.89 9.7 5.5 2.7 8.2 5.5 1.8 1 1 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_11 PF17123.5 KXH49343.1 - 1.8 8.4 4.8 4.9 7.0 4.8 1.8 1 0 0 1 1 1 0 RING-like zinc finger PALP PF00291.25 KXH49344.1 - 1.9e-64 217.9 0.2 1e-63 215.5 0.2 1.8 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme HRDC PF00570.23 KXH49344.1 - 0.0072 16.3 0.0 1.8 8.6 0.0 2.9 3 0 0 3 3 3 2 HRDC domain DUF3343 PF11823.8 KXH49344.1 - 0.11 11.9 0.1 0.4 10.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3343) Transglut_core PF01841.19 KXH49344.1 - 0.13 12.8 0.0 0.25 11.8 0.0 1.4 1 0 0 1 1 1 0 Transglutaminase-like superfamily TPMT PF05724.11 KXH49345.1 - 4e-27 95.3 0.0 5.8e-26 91.5 0.0 2.1 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_25 PF13649.6 KXH49345.1 - 3.5e-09 37.2 0.0 4.1e-06 27.4 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH49345.1 - 2.6e-07 30.5 0.0 2.4e-05 24.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH49345.1 - 9.9e-07 29.3 0.0 5.5e-05 23.7 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXH49345.1 - 4.3e-06 26.7 0.0 6.7e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH49345.1 - 4.7e-05 24.1 0.0 0.00017 22.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain N2227 PF07942.12 KXH49345.1 - 0.017 14.3 0.0 0.025 13.8 0.0 1.1 1 0 0 1 1 1 0 N2227-like protein TehB PF03848.14 KXH49345.1 - 0.029 13.8 0.0 0.048 13.1 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB OTU PF02338.19 KXH49346.1 - 2.1e-24 86.5 0.0 7.2e-24 84.7 0.0 1.9 2 1 0 2 2 2 1 OTU-like cysteine protease PAF-AH_p_II PF03403.13 KXH49346.1 - 0.00024 19.7 1.8 0.00044 18.9 1.8 1.3 1 0 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Peptidase_C65 PF10275.9 KXH49346.1 - 0.0081 15.6 0.0 0.32 10.4 0.0 2.6 3 0 0 3 3 3 1 Peptidase C65 Otubain Gp5_OB PF06714.11 KXH49346.1 - 0.06 13.6 0.2 0.15 12.3 0.2 1.6 1 0 0 1 1 1 0 Gp5 N-terminal OB domain DUF1387 PF07139.11 KXH49346.1 - 1.1 8.9 16.0 2.1 8.0 16.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1387) Draxin PF15550.6 KXH49346.1 - 5.3 6.8 11.5 6.6 6.5 11.5 1.1 1 0 0 1 1 1 0 Draxin Mcp5_PH PF12814.7 KXH49347.1 - 6.1e-48 162.0 0.0 1.3e-47 160.9 0.0 1.6 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology Fez1 PF06818.15 KXH49347.1 - 0.0088 16.5 16.6 0.021 15.3 16.6 1.6 1 0 0 1 1 1 1 Fez1 TPR_MLP1_2 PF07926.12 KXH49347.1 - 0.0094 16.0 19.2 0.0094 16.0 19.2 2.3 1 1 1 2 2 2 1 TPR/MLP1/MLP2-like protein DUF724 PF05266.14 KXH49347.1 - 0.0094 15.8 4.2 0.019 14.8 4.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF724) PH_12 PF16457.5 KXH49347.1 - 0.12 12.9 2.7 0.2 12.2 0.1 2.8 3 1 0 3 3 2 0 Pleckstrin homology domain CENP-F_leu_zip PF10473.9 KXH49347.1 - 0.86 9.6 14.5 1.5 8.8 14.5 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CENP-H PF05837.12 KXH49347.1 - 2.1 8.8 10.9 7 7.1 0.8 2.7 2 0 0 2 2 2 0 Centromere protein H (CENP-H) SlyX PF04102.12 KXH49347.1 - 3 8.5 8.7 1.3 9.7 4.4 2.6 1 1 1 2 2 2 0 SlyX UPF0242 PF06785.11 KXH49347.1 - 3.5 7.7 8.7 6.4 6.8 8.7 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus ADIP PF11559.8 KXH49347.1 - 4 7.5 22.7 4.8 7.2 6.3 2.4 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Golgin_A5 PF09787.9 KXH49347.1 - 5.5 6.4 16.2 10 5.5 16.2 1.4 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF4407 PF14362.6 KXH49347.1 - 9.1 5.5 10.7 16 4.7 10.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) MerC PF03203.14 KXH49348.1 - 0.28 11.6 1.2 0.46 11.0 1.2 1.3 1 0 0 1 1 1 0 MerC mercury resistance protein HAD_2 PF13419.6 KXH49350.1 - 1.4e-05 25.2 0.0 4.8e-05 23.5 0.0 1.9 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KXH49350.1 - 0.0005 20.4 0.0 0.00081 19.7 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KXH49350.1 - 0.0029 17.6 0.3 0.0076 16.3 0.3 1.8 1 1 0 1 1 1 1 HAD-hyrolase-like CENP-N PF05238.13 KXH49381.1 - 5.9e-133 444.2 0.0 6.7e-133 444.0 0.0 1.0 1 0 0 1 1 1 1 Kinetochore protein CHL4 like TatD_DNase PF01026.21 KXH49382.1 - 2.4e-48 164.8 0.0 4.9e-48 163.7 0.0 1.5 1 1 0 1 1 1 1 TatD related DNase Ribonuc_red_lgC PF02867.15 KXH49383.1 - 8e-194 645.0 0.0 1e-193 644.7 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 KXH49383.1 - 2.8e-24 84.9 0.0 6.3e-23 80.6 0.0 2.6 2 0 0 2 2 2 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 KXH49383.1 - 5.6e-17 62.1 0.0 1.2e-16 61.0 0.0 1.6 1 0 0 1 1 1 1 ATP cone domain CFEM PF05730.11 KXH49384.1 - 1.7e-08 34.4 8.0 3.3e-08 33.5 8.0 1.4 1 0 0 1 1 1 1 CFEM domain NAD_binding_4 PF07993.12 KXH49398.1 - 4.5e-28 98.1 0.0 6.6e-28 97.6 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 KXH49398.1 - 4.8e-27 94.6 0.0 7.2e-27 94.0 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 KXH49398.1 - 6.4e-10 38.9 0.0 1.1e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KXH49398.1 - 1.5e-06 28.4 0.0 3.2e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Semialdhyde_dh PF01118.24 KXH49398.1 - 0.066 13.7 0.0 0.19 12.2 0.0 1.8 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 KXH49398.1 - 0.13 11.6 0.0 0.42 10.0 0.0 1.7 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase RhoGAP PF00620.27 KXH49398.1 - 0.18 11.6 0.0 0.4 10.5 0.0 1.5 1 0 0 1 1 1 0 RhoGAP domain DUF805 PF05656.14 KXH49399.1 - 1.4 9.3 6.8 0.82 10.1 0.7 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF805) Toxin_16 PF07945.11 KXH49400.1 - 0.4 10.6 6.8 0.42 10.6 0.2 3.0 2 0 0 2 2 2 0 Janus-atracotoxin Aminotran_3 PF00202.21 KXH49401.1 - 6.9e-42 143.5 0.0 6.5e-19 67.9 0.0 3.1 3 0 0 3 3 3 3 Aminotransferase class-III AAA_26 PF13500.6 KXH49401.1 - 2.1e-14 53.8 0.0 3.3e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain Aminotran_1_2 PF00155.21 KXH49402.1 - 4.9e-31 108.2 0.0 8.2e-31 107.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KXH49402.1 - 0.034 12.7 0.0 0.051 12.1 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme COesterase PF00135.28 KXH49403.1 - 1.7e-85 287.9 0.1 2.1e-85 287.6 0.1 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXH49403.1 - 1.7e-07 31.3 0.1 5.8e-07 29.6 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KXH49403.1 - 0.0047 16.4 0.2 0.01 15.3 0.2 1.6 1 0 0 1 1 1 1 Prolyl oligopeptidase family Tyrosinase PF00264.20 KXH49404.1 - 6.2e-50 170.5 0.3 9.7e-50 169.9 0.3 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase MFS_1 PF07690.16 KXH49405.1 - 2.8e-19 69.2 61.8 5.1e-17 61.8 36.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Asparaginase PF00710.20 KXH49407.1 - 2.3e-27 95.8 0.0 3.7e-27 95.1 0.0 1.3 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 KXH49407.1 - 4.8e-13 49.3 0.0 1.2e-12 48.1 0.0 1.7 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain FTR1 PF03239.14 KXH49408.1 - 5.6e-75 252.3 9.7 7.1e-75 252.0 9.7 1.1 1 0 0 1 1 1 1 Iron permease FTR1 family Cu-oxidase_2 PF07731.14 KXH49409.1 - 2.8e-40 137.2 0.5 2.8e-40 137.2 0.5 3.5 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase PF00394.22 KXH49409.1 - 2.6e-39 134.9 0.7 1.2e-35 123.0 0.1 3.3 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 KXH49409.1 - 2.1e-27 95.5 4.2 8.5e-25 87.1 0.4 3.5 3 1 0 3 3 3 2 Multicopper oxidase Cupredoxin_1 PF13473.6 KXH49409.1 - 0.068 13.3 0.0 3.3 7.9 0.0 2.6 1 1 0 1 1 1 0 Cupredoxin-like domain DUF5060 PF16586.5 KXH49409.1 - 0.099 13.0 0.0 0.56 10.6 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5060) FlgH PF02107.16 KXH49410.1 - 0.49 10.0 3.2 0.75 9.4 3.2 1.2 1 0 0 1 1 1 0 Flagellar L-ring protein Amnionless PF14828.6 KXH49412.1 - 0.0008 18.4 0.0 0.0011 17.9 0.0 1.2 1 0 0 1 1 1 1 Amnionless LapA_dom PF06305.11 KXH49412.1 - 0.0015 18.3 0.1 0.0025 17.6 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide assembly protein A domain Trp_oprn_chp PF09534.10 KXH49412.1 - 0.0037 17.1 0.2 0.0069 16.2 0.2 1.4 1 0 0 1 1 1 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF2613 PF11021.8 KXH49412.1 - 0.0065 16.6 0.3 0.024 14.7 0.2 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2613) EphA2_TM PF14575.6 KXH49412.1 - 0.047 14.6 0.0 0.1 13.5 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Colicin_V PF02674.16 KXH49412.1 - 0.058 13.4 0.0 0.09 12.7 0.0 1.2 1 0 0 1 1 1 0 Colicin V production protein VSP PF03302.13 KXH49412.1 - 0.11 11.4 7.1 0.29 9.9 6.5 1.7 1 1 1 2 2 2 0 Giardia variant-specific surface protein DUF3042 PF11240.8 KXH49412.1 - 0.13 12.3 0.1 0.29 11.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3042) Zn_clus PF00172.18 KXH49413.1 - 6.2e-07 29.4 6.2 6.2e-07 29.4 6.2 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Inhibitor_I36 PF03995.13 KXH49414.1 - 0.02 14.8 1.2 0.037 14.0 1.2 1.5 1 1 0 1 1 1 0 Peptidase inhibitor family I36 Glyco_hydro_35 PF01301.19 KXH49415.1 - 2e-88 297.1 0.1 3.7e-88 296.2 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.9 KXH49415.1 - 9.1e-57 191.8 0.8 1.9e-56 190.7 0.8 1.6 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.6 KXH49415.1 - 2.4e-52 176.3 4.6 6.1e-32 110.6 0.0 2.8 3 0 0 3 3 3 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.6 KXH49415.1 - 9.3e-22 76.4 0.0 3.9e-21 74.4 0.0 2.1 2 0 0 2 2 2 1 Beta-galactosidase, domain 3 Glyco_hydro_42 PF02449.15 KXH49415.1 - 1.7e-06 27.6 0.2 0.00036 20.0 0.2 2.4 1 1 1 2 2 2 2 Beta-galactosidase Cellulase PF00150.18 KXH49415.1 - 1.6e-05 24.5 3.3 1.8e-05 24.3 0.1 2.4 3 0 0 3 3 3 1 Cellulase (glycosyl hydrolase family 5) Sorting_nexin PF03700.13 KXH49418.1 - 0.46 11.1 8.7 1.2 9.7 8.7 1.7 1 0 0 1 1 1 0 Sorting nexin, N-terminal domain NmrA PF05368.13 KXH49419.1 - 9e-14 51.6 0.0 1.3e-13 51.1 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXH49419.1 - 9.9e-10 38.6 0.0 1.8e-09 37.8 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KXH49419.1 - 3e-08 33.4 0.1 9e-07 28.6 0.1 2.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 KXH49419.1 - 0.00054 20.4 0.0 0.0013 19.1 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.10 KXH49419.1 - 0.0011 18.9 0.0 0.0019 18.1 0.0 1.4 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 KXH49419.1 - 0.019 15.2 0.0 0.033 14.5 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain RmlD_sub_bind PF04321.17 KXH49419.1 - 0.022 13.9 0.1 0.033 13.3 0.1 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain Shikimate_DH PF01488.20 KXH49419.1 - 0.027 14.6 0.1 0.058 13.5 0.0 1.6 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DapB_N PF01113.20 KXH49419.1 - 0.056 13.6 0.0 0.12 12.6 0.0 1.5 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus LpxI_N PF17930.1 KXH49419.1 - 0.18 11.7 0.0 0.76 9.7 0.0 1.9 2 0 0 2 2 2 0 LpxI N-terminal domain Methyltransf_2 PF00891.18 KXH49420.1 - 1.6e-26 92.9 0.0 4.7e-24 84.9 0.0 2.4 2 0 0 2 2 2 2 O-methyltransferase domain Methyltransf_23 PF13489.6 KXH49420.1 - 3.9e-24 85.3 0.0 1.5e-21 76.9 0.0 2.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH49420.1 - 1.7e-16 60.7 0.0 2.8e-12 47.2 0.0 2.8 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 KXH49420.1 - 1.1e-12 48.4 0.0 1.2e-10 41.9 0.0 2.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH49420.1 - 5.1e-12 46.4 0.0 9.8e-09 35.9 0.0 3.5 3 1 0 3 3 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH49420.1 - 2.7e-11 43.5 0.0 3.7e-07 30.1 0.0 3.4 2 1 0 2 2 2 2 Methyltransferase domain MTS PF05175.14 KXH49420.1 - 0.00056 19.5 0.1 1.7 8.2 0.0 3.0 2 1 0 2 2 2 2 Methyltransferase small domain CMAS PF02353.20 KXH49420.1 - 0.0048 16.2 0.0 0.0091 15.3 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.7 KXH49420.1 - 0.01 15.8 0.0 0.078 12.9 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_4 PF02390.17 KXH49420.1 - 0.046 13.2 0.0 0.15 11.5 0.0 1.8 2 0 0 2 2 2 0 Putative methyltransferase Ubie_methyltran PF01209.18 KXH49420.1 - 0.048 13.0 0.0 0.81 9.0 0.0 2.8 3 1 0 3 3 3 0 ubiE/COQ5 methyltransferase family CheR PF01739.18 KXH49420.1 - 0.061 12.8 0.0 0.64 9.5 0.0 2.1 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain Calpain_inhib PF00748.19 KXH49420.1 - 0.15 12.5 6.6 0.46 11.0 6.6 1.8 1 0 0 1 1 1 0 Calpain inhibitor HET PF06985.11 KXH49421.1 - 3.7e-25 89.0 0.1 5.8e-25 88.4 0.1 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) TRAP_alpha PF03896.16 KXH49422.1 - 1.7 7.8 3.2 3.4 6.8 3.2 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Tim54 PF11711.8 KXH49422.1 - 6.4 5.5 6.1 1.9 7.2 0.1 2.0 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Nop14 PF04147.12 KXH49422.1 - 8.1 4.5 15.4 10 4.2 15.4 1.0 1 0 0 1 1 1 0 Nop14-like family Glyco_hydro_72 PF03198.14 KXH49426.1 - 2.7e-121 404.7 0.4 3.3e-121 404.4 0.4 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 KXH49426.1 - 0.00023 20.7 0.0 0.0011 18.5 0.0 1.9 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Guanylate_kin PF00625.21 KXH49427.1 - 7.7e-62 208.2 0.0 9.5e-62 207.9 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_33 PF13671.6 KXH49427.1 - 4.2e-06 27.0 0.1 6e-05 23.2 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KXH49427.1 - 5.7e-05 23.6 0.2 0.00022 21.7 0.2 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 KXH49427.1 - 0.00015 22.3 0.2 0.00057 20.4 0.2 1.9 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KXH49427.1 - 0.0017 18.6 0.0 0.0048 17.2 0.0 1.7 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 KXH49427.1 - 0.0089 16.1 0.0 0.021 14.9 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase ATPase_2 PF01637.18 KXH49427.1 - 0.015 15.2 0.1 1.5 8.6 0.0 2.1 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea RsgA_GTPase PF03193.16 KXH49427.1 - 0.027 14.4 0.0 0.062 13.2 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase dNK PF01712.19 KXH49427.1 - 0.029 14.2 0.0 2.5 7.9 0.0 2.2 2 0 0 2 2 2 0 Deoxynucleoside kinase ABC_tran PF00005.27 KXH49427.1 - 0.087 13.3 0.1 0.15 12.6 0.1 1.7 1 1 0 1 1 1 0 ABC transporter Rad17 PF03215.15 KXH49427.1 - 0.092 12.7 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_28 PF13521.6 KXH49427.1 - 0.096 12.9 0.0 1.3 9.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 KXH49427.1 - 0.13 12.3 0.0 0.61 10.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain Septin PF00735.18 KXH49428.1 - 2e-112 375.1 0.7 2.4e-112 374.8 0.7 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 KXH49428.1 - 1.1e-07 32.0 0.0 2.2e-07 30.9 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KXH49428.1 - 4.4e-06 26.4 0.2 0.0031 17.1 0.0 2.3 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain AIG1 PF04548.16 KXH49428.1 - 4.9e-06 26.0 0.0 8.6e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 AIG1 family RsgA_GTPase PF03193.16 KXH49428.1 - 1.1e-05 25.4 0.2 0.00032 20.6 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 KXH49428.1 - 0.001 19.1 0.2 1.5 8.9 0.1 2.6 1 1 1 2 2 2 2 Dynamin family NB-ARC PF00931.22 KXH49428.1 - 0.0032 16.7 0.1 0.0057 15.9 0.1 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_7 PF12775.7 KXH49428.1 - 0.0051 16.4 0.0 0.034 13.7 0.0 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_16 PF13191.6 KXH49428.1 - 0.0056 17.1 0.0 0.027 14.8 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KXH49428.1 - 0.0061 16.8 0.0 0.015 15.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 KXH49428.1 - 0.01 16.3 0.2 0.019 15.5 0.2 1.7 1 1 0 1 1 1 0 ABC transporter Gtr1_RagA PF04670.12 KXH49428.1 - 0.01 15.2 0.1 0.4 10.0 0.0 2.2 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region G-alpha PF00503.20 KXH49428.1 - 0.065 12.4 0.6 0.27 10.4 0.5 2.0 1 1 0 1 1 1 0 G-protein alpha subunit FtsK_SpoIIIE PF01580.18 KXH49428.1 - 0.077 12.3 0.1 0.15 11.4 0.1 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Microtub_bd PF16796.5 KXH49428.1 - 0.078 12.9 0.2 0.51 10.3 0.0 2.1 2 0 0 2 2 2 0 Microtubule binding Roc PF08477.13 KXH49428.1 - 0.1 12.8 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase DUF1542 PF07564.11 KXH49428.1 - 0.12 12.5 0.1 0.28 11.3 0.1 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1542) T2SSE PF00437.20 KXH49428.1 - 0.13 11.3 0.0 0.25 10.4 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.6 KXH49428.1 - 0.19 11.5 0.0 0.39 10.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Ribosomal_L32p PF01783.23 KXH49429.1 - 2.3e-14 53.4 6.8 3.2e-14 52.9 6.8 1.2 1 0 0 1 1 1 1 Ribosomal L32p protein family zf-ribbon_3 PF13248.6 KXH49429.1 - 0.024 14.1 6.2 0.038 13.4 6.2 1.3 1 0 0 1 1 1 0 zinc-ribbon domain HypA PF01155.19 KXH49429.1 - 0.05 13.6 0.1 0.057 13.4 0.1 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF4428 PF14471.6 KXH49429.1 - 0.052 13.5 2.3 0.12 12.3 2.4 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4428) zf-ACC PF17848.1 KXH49429.1 - 8.4 6.6 9.8 6.4e+02 0.5 9.8 2.5 2 1 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain WD40 PF00400.32 KXH49430.1 - 5.3e-20 71.4 14.8 2.8e-08 34.3 0.5 6.7 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXH49430.1 - 5.1e-14 52.4 2.9 0.00042 20.6 0.0 4.4 1 1 3 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KXH49430.1 - 0.00026 20.4 0.0 0.0015 17.9 0.0 2.0 2 1 0 2 2 2 1 WD40-like domain eIF2A PF08662.11 KXH49430.1 - 0.0027 17.6 0.8 0.013 15.3 0.1 2.4 2 2 2 4 4 4 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KXH49430.1 - 0.0029 16.6 0.5 2.8 6.8 0.0 3.5 2 2 2 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 KXH49430.1 - 0.003 16.9 0.1 0.6 9.4 0.0 3.2 1 1 3 4 4 4 1 Neuroblastoma-amplified sequence, N terminal Lactonase PF10282.9 KXH49430.1 - 0.0067 15.7 0.0 0.24 10.6 0.0 2.4 1 1 2 3 3 3 1 Lactonase, 7-bladed beta-propeller Coatomer_WDAD PF04053.14 KXH49430.1 - 0.034 13.2 0.0 0.034 13.2 0.0 1.1 1 0 0 1 1 1 0 Coatomer WD associated region Nup160 PF11715.8 KXH49430.1 - 0.079 11.6 0.3 0.14 10.7 0.1 1.5 2 0 0 2 2 2 0 Nucleoporin Nup120/160 FG-GAP_2 PF14312.6 KXH49430.1 - 0.88 9.9 3.7 3 8.2 1.0 2.8 2 1 0 2 2 2 0 FG-GAP repeat DNA_pol_delta_4 PF04081.13 KXH49431.1 - 6.6e-45 152.7 2.2 9e-45 152.2 2.2 1.2 1 0 0 1 1 1 1 DNA polymerase delta, subunit 4 Q_salvage PF10343.9 KXH49432.1 - 1.4e-128 428.4 0.0 1.7e-128 428.1 0.0 1.1 1 0 0 1 1 1 1 Potential Queuosine, Q, salvage protein family DUF1563 PF07599.11 KXH49432.1 - 0.042 14.0 0.1 0.083 13.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1563) ThiF PF00899.21 KXH49433.1 - 5.7e-75 251.8 0.0 9.5e-75 251.1 0.0 1.2 1 0 0 1 1 1 1 ThiF family UAE_UbL PF14732.6 KXH49433.1 - 5.8e-25 87.7 2.7 2.6e-24 85.6 0.6 2.3 2 0 0 2 2 2 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.9 KXH49433.1 - 2e-05 24.6 7.0 7.7e-05 22.7 0.2 3.2 2 1 1 3 3 3 1 Ubiquitin-activating enzyme active site NAD_binding_7 PF13241.6 KXH49433.1 - 0.00071 20.0 0.1 0.002 18.5 0.1 1.8 1 0 0 1 1 1 1 Putative NAD(P)-binding Shikimate_DH PF01488.20 KXH49433.1 - 0.047 13.8 0.1 0.11 12.5 0.1 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Peptidase_C107 PF17222.3 KXH49433.1 - 0.08 11.9 0.0 0.3 10.0 0.0 1.8 2 0 0 2 2 2 0 Viral cysteine endopeptidase C107 Pyr_redox PF00070.27 KXH49433.1 - 0.15 12.6 0.2 4.2 8.0 0.1 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Sacchrp_dh_NADP PF03435.18 KXH49433.1 - 0.16 12.2 0.3 0.64 10.3 0.3 2.1 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Ndc1_Nup PF09531.10 KXH49433.1 - 0.88 8.2 2.5 1.5 7.4 2.5 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Pex14_N PF04695.13 KXH49433.1 - 1.2 9.7 19.1 0.081 13.6 13.6 1.8 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region dCMP_cyt_deam_1 PF00383.23 KXH49571.1 - 2.9e-25 88.1 1.1 4.9e-25 87.3 1.1 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KXH49571.1 - 8.4e-10 38.5 0.1 1.5e-09 37.7 0.1 1.4 1 0 0 1 1 1 1 MafB19-like deaminase zf-CCHC PF00098.23 KXH49571.1 - 0.00022 21.1 4.9 0.00022 21.1 4.9 2.2 2 0 0 2 2 2 1 Zinc knuckle CoaE PF01121.20 KXH49571.1 - 0.054 13.2 0.0 0.089 12.5 0.0 1.3 1 0 0 1 1 1 0 Dephospho-CoA kinase AAA_18 PF13238.6 KXH49571.1 - 0.078 13.5 0.0 0.18 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Opi1 PF08618.10 KXH49571.1 - 0.08 12.2 1.7 0.11 11.7 1.7 1.1 1 0 0 1 1 1 0 Transcription factor Opi1 zf-CCHC_4 PF14392.6 KXH49571.1 - 6.1 6.7 9.4 2.6 7.8 1.7 2.5 2 0 0 2 2 2 0 Zinc knuckle ATG7_N PF16420.5 KXH49572.1 - 5e-111 371.1 0.0 7.1e-111 370.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus ThiF PF00899.21 KXH49572.1 - 1.2e-43 149.3 0.0 1.7e-43 148.8 0.0 1.2 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 KXH49572.1 - 0.061 13.4 0.0 0.54 10.3 0.0 2.1 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase MFS_1 PF07690.16 KXH49573.1 - 3.4e-25 88.7 31.8 4.7e-25 88.2 31.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH49573.1 - 2.9e-14 52.8 8.6 2.9e-14 52.8 8.6 2.5 2 1 0 2 2 2 2 Sugar (and other) transporter DUF1772 PF08592.11 KXH49573.1 - 4.6 7.6 10.2 0.47 10.8 1.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF1772) DUF1115 PF06544.12 KXH49574.1 - 8.9e-13 48.6 0.0 1.3e-12 48.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) BLUF PF04940.12 KXH49574.1 - 0.11 12.6 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 Sensors of blue-light using FAD DnaJ PF00226.31 KXH49575.1 - 1.2e-11 44.6 0.0 1.9e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain ELFV_dehydrog PF00208.21 KXH49579.1 - 4.7e-12 46.2 0.0 9.1e-12 45.2 0.0 1.4 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 KXH49579.1 - 6.5e-07 29.3 0.0 1.2e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Glyoxalase_4 PF13669.6 KXH49579.1 - 2.4e-06 27.8 0.0 8.3e-06 26.0 0.0 2.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase PF00903.25 KXH49579.1 - 0.00014 22.0 0.0 0.00087 19.5 0.0 2.4 2 1 1 3 3 3 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Methyltransf_25 PF13649.6 KXH49580.1 - 6.5e-11 42.8 0.0 1.4e-10 41.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH49580.1 - 1.1e-09 38.2 0.0 2e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 KXH49580.1 - 3.4e-09 36.3 0.0 5e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_11 PF08241.12 KXH49580.1 - 7.4e-09 36.2 0.0 1.6e-08 35.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Dimerisation2 PF16864.5 KXH49580.1 - 0.00018 21.4 0.0 0.00034 20.5 0.0 1.4 1 0 0 1 1 1 1 Dimerisation domain Ubie_methyltran PF01209.18 KXH49580.1 - 0.00086 18.7 0.0 0.0024 17.2 0.0 1.7 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KXH49580.1 - 0.002 18.9 0.0 0.006 17.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.17 KXH49580.1 - 0.013 14.9 0.0 0.021 14.3 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase MTS PF05175.14 KXH49580.1 - 0.025 14.1 0.0 0.052 13.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase small domain TetR_C_27 PF17935.1 KXH49580.1 - 0.033 14.3 0.0 0.063 13.3 0.0 1.5 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain AMP-binding PF00501.28 KXH49581.1 - 1.7e-78 264.2 0.0 3.3e-39 134.7 0.0 2.1 1 1 1 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 KXH49581.1 - 1.7e-10 41.8 0.1 3.4e-10 40.7 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Mannosyl_trans3 PF11051.8 KXH49582.1 - 2.7e-35 122.1 0.0 9.3e-35 120.3 0.0 1.8 1 1 0 1 1 1 1 Mannosyltransferase putative DUF3328 PF11807.8 KXH49582.1 - 0.0088 15.8 0.6 0.017 14.9 0.6 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) SKG6 PF08693.10 KXH49583.1 - 0.00014 21.2 0.0 0.00031 20.1 0.0 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain AJAP1_PANP_C PF15298.6 KXH49583.1 - 0.0026 18.0 1.0 0.0038 17.5 1.0 1.2 1 0 0 1 1 1 1 AJAP1/PANP C-terminus Alpha_GJ PF03229.13 KXH49583.1 - 0.022 15.3 6.9 0.039 14.5 6.9 1.3 1 0 0 1 1 1 0 Alphavirus glycoprotein J TMEM154 PF15102.6 KXH49583.1 - 0.03 14.2 0.2 0.046 13.6 0.2 1.3 1 0 0 1 1 1 0 TMEM154 protein family Sporozoite_P67 PF05642.11 KXH49583.1 - 0.065 11.3 6.6 0.076 11.1 6.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Mucin PF01456.17 KXH49583.1 - 0.79 9.7 17.6 0.2 11.6 13.4 1.9 2 0 0 2 2 2 0 Mucin-like glycoprotein MGC-24 PF05283.11 KXH49583.1 - 2.1 8.8 7.8 4.2 7.8 7.8 1.5 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Zn_clus PF00172.18 KXH49585.1 - 6e-06 26.3 8.8 1e-05 25.5 8.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KXH49585.1 - 0.004 16.0 0.4 0.0081 15.0 0.1 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Arg_decarb_HB PF17810.1 KXH49585.1 - 0.07 13.4 0.1 0.13 12.6 0.1 1.4 1 0 0 1 1 1 0 Arginine decarboxylase helical bundle domain Ank_2 PF12796.7 KXH49586.1 - 9.5e-42 141.5 0.1 2.1e-11 44.3 0.0 5.6 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXH49586.1 - 4.4e-36 122.8 0.9 4.6e-07 30.3 0.0 6.9 5 1 3 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXH49586.1 - 5.7e-33 109.2 0.0 0.0039 17.6 0.0 9.8 9 0 0 9 9 9 8 Ankyrin repeat Ank_5 PF13857.6 KXH49586.1 - 1.1e-27 95.8 2.4 0.00038 20.7 0.0 8.0 4 2 5 9 9 9 8 Ankyrin repeats (many copies) Ank PF00023.30 KXH49586.1 - 2e-23 81.7 0.3 0.0044 17.4 0.0 9.0 9 0 0 9 9 9 7 Ankyrin repeat AAA_16 PF13191.6 KXH49586.1 - 0.072 13.5 0.0 0.32 11.4 0.0 2.1 1 0 0 1 1 1 0 AAA ATPase domain ketoacyl-synt PF00109.26 KXH49587.1 - 1.5e-74 250.8 0.0 3e-74 249.8 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KXH49587.1 - 7e-61 205.3 2.1 1.2e-60 204.5 0.3 2.4 3 0 0 3 3 3 1 KR domain Acyl_transf_1 PF00698.21 KXH49587.1 - 4.1e-56 190.8 0.1 6.9e-56 190.1 0.1 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 KXH49587.1 - 3e-47 161.3 0.0 4.9e-47 160.6 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 KXH49587.1 - 4.1e-43 146.1 0.4 2.1e-41 140.7 0.0 3.2 3 0 0 3 3 3 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KXH49587.1 - 1.1e-19 71.0 0.1 3.6e-19 69.3 0.1 2.0 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 KXH49587.1 - 1.2e-15 57.5 1.1 1.8e-14 53.6 0.1 2.6 2 0 0 2 2 2 1 short chain dehydrogenase ADH_zinc_N PF00107.26 KXH49587.1 - 1.5e-11 44.4 0.1 1e-10 41.7 0.0 2.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXH49587.1 - 3.6e-10 41.0 0.0 1.4e-09 39.1 0.0 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short_C2 PF13561.6 KXH49587.1 - 5.2e-10 39.3 1.6 1e-09 38.3 0.4 2.1 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase ADH_N PF08240.12 KXH49587.1 - 2.5e-07 30.5 0.0 7e-07 29.1 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.25 KXH49587.1 - 1.6e-05 25.1 0.3 3.4e-05 24.1 0.3 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.23 KXH49587.1 - 0.046 13.1 0.9 0.076 12.4 0.2 1.7 2 0 0 2 2 2 0 Thiolase, N-terminal domain Polysacc_synt_2 PF02719.15 KXH49587.1 - 0.046 12.9 0.0 0.084 12.0 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein FSH1 PF03959.13 KXH49588.1 - 1.5e-31 109.7 0.0 4.8e-31 108.1 0.0 1.7 1 1 0 1 1 1 1 Serine hydrolase (FSH1) ABC_membrane PF00664.23 KXH49589.1 - 1.2e-79 267.9 44.8 1.7e-46 159.1 13.0 2.4 2 1 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KXH49589.1 - 8.3e-63 211.0 0.0 1.6e-32 112.8 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KXH49589.1 - 9.5e-16 57.9 5.9 0.00039 19.9 0.0 4.2 2 2 1 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KXH49589.1 - 9e-09 35.0 1.0 0.0025 17.5 0.2 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 KXH49589.1 - 2.9e-08 34.1 1.2 0.011 16.0 0.0 3.8 2 2 0 2 2 2 2 AAA domain ABC_ATPase PF09818.9 KXH49589.1 - 7.9e-08 31.5 1.6 0.01 14.7 0.1 3.9 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_23 PF13476.6 KXH49589.1 - 2.2e-07 31.6 0.4 0.021 15.3 0.2 2.3 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KXH49589.1 - 6.9e-07 29.2 0.5 0.023 14.4 0.1 3.4 3 1 0 3 3 3 2 AAA domain AAA_21 PF13304.6 KXH49589.1 - 1.5e-06 28.2 1.1 0.023 14.5 0.2 3.0 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KXH49589.1 - 2.2e-06 28.2 1.5 0.11 12.9 0.0 3.3 2 1 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KXH49589.1 - 1.6e-05 24.9 0.0 0.14 12.1 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_25 PF13481.6 KXH49589.1 - 2.9e-05 23.7 0.2 0.33 10.5 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_15 PF13175.6 KXH49589.1 - 0.00012 21.9 0.0 0.18 11.5 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_18 PF13238.6 KXH49589.1 - 0.00016 22.2 0.0 0.85 10.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.6 KXH49589.1 - 0.00087 19.1 0.1 0.98 9.1 0.1 2.5 2 0 0 2 2 2 2 AAA domain ATP_bind_1 PF03029.17 KXH49589.1 - 0.0014 18.5 0.1 2 8.1 0.0 2.4 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein AAA PF00004.29 KXH49589.1 - 0.0015 19.0 3.0 29 5.1 0.0 4.4 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 KXH49589.1 - 0.0016 18.4 0.0 2 8.3 0.0 2.4 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_5 PF07728.14 KXH49589.1 - 0.0023 17.9 0.0 2.7 8.0 0.0 2.9 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KXH49589.1 - 0.0031 17.7 0.2 4.4 7.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 KXH49589.1 - 0.0041 16.3 0.1 4.7 6.3 0.0 3.1 3 0 0 3 3 3 0 NB-ARC domain SbcCD_C PF13558.6 KXH49589.1 - 0.0049 17.1 2.4 3.3 8.0 0.3 3.9 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit SRP54 PF00448.22 KXH49589.1 - 0.0086 15.7 1.0 2.8 7.5 0.0 2.9 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain AAA_28 PF13521.6 KXH49589.1 - 0.012 15.8 0.3 2.9 8.1 0.1 2.5 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 KXH49589.1 - 0.013 15.2 0.2 6.2 6.5 0.0 3.8 4 0 0 4 4 4 0 IstB-like ATP binding protein Cytidylate_kin PF02224.18 KXH49589.1 - 0.014 15.2 0.0 4.3 7.0 0.0 2.5 2 0 0 2 2 2 0 Cytidylate kinase ATPase PF06745.13 KXH49589.1 - 0.017 14.5 1.0 0.87 8.9 0.1 2.6 3 0 0 3 3 2 0 KaiC DUF87 PF01935.17 KXH49589.1 - 0.022 14.9 0.5 2.6 8.1 0.0 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_7 PF12775.7 KXH49589.1 - 0.023 14.2 0.0 4.2 6.8 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_19 PF13245.6 KXH49589.1 - 0.048 14.0 0.9 20 5.5 0.0 3.3 4 0 0 4 4 2 0 AAA domain TniB PF05621.11 KXH49589.1 - 0.053 12.9 0.0 10 5.5 0.0 3.1 3 0 0 3 3 3 0 Bacterial TniB protein NACHT PF05729.12 KXH49589.1 - 0.067 13.1 0.4 6 6.8 0.0 2.5 2 0 0 2 2 2 0 NACHT domain ATP-synt_ab PF00006.25 KXH49589.1 - 0.083 12.5 0.0 12 5.5 0.0 2.5 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_14 PF13173.6 KXH49589.1 - 0.096 12.7 0.1 24 5.0 0.0 3.3 3 0 0 3 3 3 0 AAA domain APS_kinase PF01583.20 KXH49589.1 - 0.098 12.5 0.1 16 5.3 0.0 2.4 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_17 PF13207.6 KXH49589.1 - 0.1 13.0 0.0 13 6.2 0.0 2.8 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 KXH49589.1 - 0.13 11.9 0.3 12 5.5 0.1 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain dNK PF01712.19 KXH49589.1 - 0.14 11.9 0.1 14 5.5 0.0 2.5 2 0 0 2 2 2 0 Deoxynucleoside kinase PRK PF00485.18 KXH49589.1 - 0.16 11.7 0.1 12 5.6 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_11 PF13086.6 KXH49589.1 - 0.18 11.5 0.1 11 5.7 0.0 2.9 2 1 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KXH49589.1 - 0.32 11.1 1.2 29 4.8 0.0 2.9 3 0 0 3 3 3 0 50S ribosome-binding GTPase Cyt-b5 PF00173.28 KXH49590.1 - 9.2e-15 54.6 0.0 2.1e-14 53.4 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain IDO PF01231.18 KXH49590.1 - 2.2e-11 43.2 0.0 1.1e-10 40.9 0.0 1.9 2 0 0 2 2 2 1 Indoleamine 2,3-dioxygenase FAD_binding_1 PF00667.20 KXH49590.1 - 1.8e-10 40.8 0.0 2.3e-09 37.2 0.0 2.4 2 1 0 2 2 2 1 FAD binding domain NAD_binding_1 PF00175.21 KXH49590.1 - 7e-09 36.3 0.0 1.7e-08 35.0 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Astro_capsid_p PF12226.8 KXH49590.1 - 0.27 10.4 0.1 0.42 9.7 0.1 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein DNA_pol3_beta_3 PF02768.15 KXH49591.1 - 0.076 12.9 0.2 9.3 6.1 0.0 2.9 2 1 1 3 3 3 0 DNA polymerase III beta subunit, C-terminal domain Aldedh PF00171.22 KXH49592.1 - 1.6e-157 524.7 0.1 2e-157 524.5 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family NCD1 PF04904.13 KXH49592.1 - 0.059 13.4 0.0 0.15 12.1 0.0 1.7 1 0 0 1 1 1 0 NAB conserved region 1 (NCD1) Mersacidin PF16934.5 KXH49592.1 - 3.9 7.3 7.5 0.92 9.3 0.3 2.5 2 0 0 2 2 2 0 Two-component Enterococcus faecalis cytolysin (EFC) GMC_oxred_N PF00732.19 KXH49594.1 - 2.5e-54 184.7 0.0 3.1e-54 184.4 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXH49594.1 - 2.3e-36 125.5 0.0 3.6e-36 124.8 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KXH49594.1 - 5.2e-07 29.1 0.1 0.0064 15.6 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 KXH49594.1 - 1.2e-05 24.5 0.0 1.8e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 KXH49594.1 - 4e-05 23.7 0.1 0.00048 20.3 0.1 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXH49594.1 - 5.7e-05 22.5 0.0 0.0071 15.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXH49594.1 - 0.00051 19.7 0.3 0.0027 17.3 0.1 2.2 3 0 0 3 3 3 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KXH49594.1 - 0.018 13.9 0.0 0.027 13.3 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox PF00070.27 KXH49594.1 - 0.092 13.3 0.1 1.6 9.3 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXH49594.1 - 0.11 11.7 0.0 0.26 10.5 0.0 1.5 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.14 KXH49594.1 - 0.22 10.2 0.1 0.76 8.4 0.0 1.7 2 0 0 2 2 2 0 HI0933-like protein Pectinesterase PF01095.19 KXH49595.1 - 8.4e-40 136.3 8.8 1.4e-39 135.6 8.8 1.3 1 0 0 1 1 1 1 Pectinesterase Pec_lyase_C PF00544.19 KXH49595.1 - 2.5e-20 73.0 11.8 2.5e-19 69.7 11.4 2.6 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 KXH49595.1 - 0.0007 19.5 30.2 0.023 14.5 9.5 4.1 2 2 1 4 4 4 2 Right handed beta helix region MFS_1 PF07690.16 KXH49596.1 - 8.1e-19 67.8 39.5 1.4e-10 40.7 24.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily SPX PF03105.19 KXH49598.1 - 5.4e-11 43.0 15.7 6.4e-06 26.3 0.0 4.0 2 1 2 4 4 4 3 SPX domain DUF998 PF06197.13 KXH49598.1 - 0.0054 16.3 2.8 0.0083 15.7 2.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF998) Chromate_transp PF02417.15 KXH49598.1 - 0.01 16.0 0.5 0.014 15.5 0.5 1.2 1 0 0 1 1 1 0 Chromate transporter Glyco_transf_21 PF13506.6 KXH49598.1 - 0.1 12.0 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 21 Fungal_trans PF04082.18 KXH49599.1 - 2.3e-09 36.7 0.9 4e-09 35.9 0.1 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH49599.1 - 2.3e-05 24.4 15.4 2.3e-05 24.4 15.4 2.4 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acetyltransf_1 PF00583.25 KXH49600.1 - 2.3e-06 27.8 0.0 3.3e-06 27.3 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXH49600.1 - 1.8e-05 25.1 0.0 3.3e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KXH49600.1 - 0.00078 19.4 0.0 0.0014 18.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KXH49600.1 - 0.0015 18.6 0.0 0.016 15.3 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXH49600.1 - 0.13 12.3 0.0 0.35 10.9 0.0 1.7 1 1 0 1 1 1 0 FR47-like protein PAN_4 PF14295.6 KXH49603.1 - 2.9e-05 23.9 0.4 6.7e-05 22.7 0.4 1.7 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.26 KXH49603.1 - 0.0015 18.5 0.1 0.003 17.5 0.1 1.5 1 0 0 1 1 1 1 PAN domain B277 PF17623.2 KXH49603.1 - 0.097 11.7 0.4 0.15 11.2 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF5560 PF17715.1 KXH49604.1 - 0.013 15.0 2.7 0.18 11.2 0.2 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5560) Amelin PF05111.12 KXH49604.1 - 0.065 12.4 0.2 0.095 11.8 0.2 1.2 1 0 0 1 1 1 0 Ameloblastin precursor (Amelin) Methyltransf_25 PF13649.6 KXH49606.1 - 2e-05 25.2 0.0 5.8e-05 23.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXH49606.1 - 0.0004 20.3 0.0 0.00064 19.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH49606.1 - 0.009 15.8 0.0 0.084 12.7 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH49606.1 - 0.011 16.4 0.0 0.032 14.9 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 KXH49606.1 - 0.19 12.5 0.0 0.52 11.1 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain DHDPS PF00701.22 KXH49607.1 - 7e-18 64.3 0.0 3.5e-16 58.8 0.0 2.1 1 1 1 2 2 2 2 Dihydrodipicolinate synthetase family LPMO_10 PF03067.15 KXH49608.1 - 3.2e-14 54.0 0.6 4.7e-14 53.5 0.6 1.2 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading N_BRCA1_IG PF16158.5 KXH49608.1 - 0.0042 17.8 0.1 0.066 13.9 0.0 2.5 1 1 2 3 3 3 1 Ig-like domain from next to BRCA1 gene Serglycin PF04360.12 KXH49608.1 - 0.037 14.0 2.3 0.071 13.1 2.3 1.4 1 0 0 1 1 1 0 Serglycin Peptidase_M20 PF01546.28 KXH49609.1 - 1.7e-25 90.0 0.0 5.3e-25 88.3 0.0 1.8 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KXH49609.1 - 8e-07 29.0 0.0 2.5e-06 27.3 0.0 1.9 2 0 0 2 2 2 1 Peptidase dimerisation domain WSC PF01822.19 KXH49610.1 - 2.7e-55 184.5 56.0 4.7e-19 68.4 10.4 4.8 4 0 0 4 4 4 4 WSC domain ASH PF15780.5 KXH49610.1 - 5.3e-07 29.8 0.4 0.02 15.1 0.0 2.9 2 0 0 2 2 2 2 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin DUF1573 PF07610.11 KXH49610.1 - 0.0035 17.3 0.0 11 6.2 0.0 3.5 3 0 0 3 3 3 2 Protein of unknown function (DUF1573) TRP PF06011.12 KXH49611.1 - 2.2e-17 63.0 19.8 5.4e-13 48.5 11.6 3.0 2 1 0 2 2 2 2 Transient receptor potential (TRP) ion channel HemY_N PF07219.13 KXH49611.1 - 4.7 7.5 8.7 2 8.7 0.2 3.6 4 0 0 4 4 4 0 HemY protein N-terminus DUF3632 PF12311.8 KXH49612.1 - 8.7e-18 65.4 0.5 1.7e-17 64.4 0.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) FAD_binding_4 PF01565.23 KXH49613.1 - 1.3e-24 86.5 2.2 2.9e-24 85.4 2.2 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KXH49613.1 - 1.3e-10 41.2 0.7 2.9e-10 40.1 0.7 1.6 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.10 KXH49613.1 - 0.025 14.0 0.0 0.053 12.9 0.0 1.4 2 0 0 2 2 2 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding Prismane PF03063.20 KXH49614.1 - 0.15 10.7 0.4 0.2 10.3 0.4 1.1 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family MFS_1 PF07690.16 KXH49615.1 - 3.1e-29 102.0 35.1 4.2e-26 91.7 21.7 2.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH49615.1 - 5.5e-14 51.9 12.3 1.5e-13 50.5 0.2 2.4 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_3 PF05977.13 KXH49615.1 - 3.1e-05 22.6 5.6 0.025 13.0 0.2 2.2 2 0 0 2 2 2 2 Transmembrane secretion effector DUF1640 PF07798.11 KXH49617.1 - 4.9e-56 189.5 8.5 6.6e-56 189.1 8.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) GNAT_acetyltr_2 PF13718.6 KXH49617.1 - 0.029 13.8 0.8 0.076 12.4 0.1 1.8 1 1 1 2 2 2 0 GNAT acetyltransferase 2 cwf21 PF08312.12 KXH49617.1 - 0.13 12.5 2.9 0.33 11.1 2.9 1.8 1 1 0 1 1 1 0 cwf21 domain DUF1690 PF07956.11 KXH49617.1 - 2 8.8 11.9 1.7 9.1 4.8 2.2 1 1 1 2 2 2 0 Protein of Unknown function (DUF1690) Metal_resist PF13801.6 KXH49617.1 - 2.1 8.5 6.7 3.2 8.0 0.5 2.7 2 1 1 3 3 3 0 Heavy-metal resistance TPR_MLP1_2 PF07926.12 KXH49617.1 - 9.1 6.4 14.2 3.6 7.7 3.1 2.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Clathrin PF00637.20 KXH49620.1 - 9.4e-201 657.8 28.0 1.2e-32 112.8 0.6 7.7 7 0 0 7 7 7 7 Region in Clathrin and VPS Clathrin_propel PF01394.20 KXH49620.1 - 1.9e-36 122.6 0.3 5.8e-08 32.7 0.1 6.7 6 0 0 6 6 6 6 Clathrin propeller repeat Clathrin_H_link PF13838.6 KXH49620.1 - 1.2e-30 105.2 0.8 1.2e-30 105.2 0.8 2.3 2 0 0 2 2 2 1 Clathrin-H-link TPR_14 PF13428.6 KXH49620.1 - 0.00013 22.5 8.5 6.2 7.9 0.0 8.1 8 0 0 8 8 7 1 Tetratricopeptide repeat Clathrin-link PF09268.10 KXH49620.1 - 0.012 14.9 0.4 0.031 13.7 0.4 1.8 1 0 0 1 1 1 0 Clathrin, heavy-chain linker PQQ_2 PF13360.6 KXH49620.1 - 0.038 13.6 0.0 4.6 6.8 0.1 3.1 3 0 0 3 3 3 0 PQQ-like domain TPR_7 PF13176.6 KXH49620.1 - 0.062 13.4 7.3 35 4.7 0.0 6.7 8 0 0 8 8 8 0 Tetratricopeptide repeat PPR PF01535.20 KXH49620.1 - 0.084 13.2 0.1 42 4.7 0.0 4.7 4 0 0 4 4 3 0 PPR repeat Coatomer_WDAD PF04053.14 KXH49620.1 - 0.1 11.6 7.4 0.44 9.5 0.3 4.0 5 0 0 5 5 5 0 Coatomer WD associated region TPR_8 PF13181.6 KXH49620.1 - 0.25 11.7 5.9 1.8 9.0 0.1 4.6 6 0 0 6 6 5 0 Tetratricopeptide repeat Vps39_1 PF10366.9 KXH49620.1 - 0.58 10.5 3.0 13 6.1 0.0 4.7 5 1 1 6 6 6 0 Vacuolar sorting protein 39 domain 1 TPR_2 PF07719.17 KXH49620.1 - 1 9.6 3.1 18 5.7 0.1 4.6 3 0 0 3 3 3 0 Tetratricopeptide repeat DPPIV_N PF00930.21 KXH49621.1 - 4.5e-108 361.2 0.4 2e-107 359.1 0.3 2.0 2 0 0 2 2 2 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 KXH49621.1 - 2.6e-53 180.6 2.1 5.6e-53 179.5 2.1 1.6 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 KXH49621.1 - 1.1e-05 26.1 2.1 0.012 16.2 0.3 3.0 2 1 1 3 3 3 2 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 KXH49621.1 - 5.9e-05 22.8 3.0 0.00079 19.1 0.7 2.3 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Zn_clus PF00172.18 KXH49622.1 - 0.37 11.0 9.0 0.73 10.0 9.0 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain SurE PF01975.17 KXH49623.1 - 1.2e-44 152.4 0.0 1.7e-44 151.9 0.0 1.1 1 0 0 1 1 1 1 Survival protein SurE GH131_N PF18271.1 KXH49624.1 - 2.7e-78 263.2 0.0 3.1e-78 263.0 0.0 1.0 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain Myb_DNA-bind_5 PF13873.6 KXH49625.1 - 0.092 12.8 0.2 0.22 11.6 0.2 1.5 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain DUF1509 PF07420.11 KXH49625.1 - 9.3 5.1 7.2 13 4.6 7.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) DNA_pol_phi PF04931.13 KXH49626.1 - 0.11 10.5 22.2 0.19 9.8 22.2 1.2 1 0 0 1 1 1 0 DNA polymerase phi DUF1676 PF07898.13 KXH49626.1 - 0.12 12.4 8.4 0.32 11.0 8.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) DUF3405 PF11885.8 KXH49626.1 - 0.92 8.0 7.7 1.4 7.5 7.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3405) TT_ORF1 PF02956.14 KXH49626.1 - 2.2 6.8 13.0 3.3 6.3 13.0 1.2 1 0 0 1 1 1 0 TT viral orf 1 Nop53 PF07767.11 KXH49626.1 - 3.7 6.9 28.5 1.3 8.4 23.1 2.0 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) zf-C2H2 PF00096.26 KXH49627.1 - 0.43 11.1 7.4 1.1 9.9 0.2 2.9 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXH49627.1 - 0.64 11.0 7.0 8.9 7.5 0.3 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_4 PF13894.6 KXH49639.1 - 4.8e-05 23.9 16.5 0.0059 17.3 3.5 4.6 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KXH49639.1 - 0.021 15.1 9.3 0.77 10.1 3.4 3.1 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 KXH49639.1 - 0.036 14.5 22.9 1.6 9.3 4.7 5.1 5 0 0 5 5 5 0 Zinc finger, C2H2 type zf-met PF12874.7 KXH49639.1 - 0.1 13.0 4.8 0.68 10.4 0.6 2.9 2 0 0 2 2 2 0 Zinc-finger of C2H2 type DUF629 PF04780.12 KXH49639.1 - 1.4 7.4 5.9 1.3 7.5 2.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF629) Kelch_6 PF13964.6 KXH49640.1 - 3e-22 78.1 1.9 3e-08 33.7 0.1 5.0 5 0 0 5 5 5 3 Kelch motif Kelch_3 PF13415.6 KXH49640.1 - 3e-22 78.4 16.9 2.7e-06 27.5 0.2 7.8 8 2 0 8 8 8 5 Galactose oxidase, central domain Kelch_4 PF13418.6 KXH49640.1 - 9.5e-22 76.8 14.0 3.2e-07 30.2 0.1 6.8 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_5 PF13854.6 KXH49640.1 - 1.2e-16 60.3 4.0 6e-05 22.9 0.0 6.5 7 0 0 7 7 7 4 Kelch motif Kelch_1 PF01344.25 KXH49640.1 - 1.9e-14 53.0 13.2 5.3e-07 29.1 0.0 5.5 7 0 0 7 7 7 3 Kelch motif Kelch_2 PF07646.15 KXH49640.1 - 1.2e-11 44.1 7.6 4.4e-06 26.4 0.8 5.8 5 1 0 5 5 5 3 Kelch motif 2Fe-2S_thioredx PF01257.19 KXH49641.1 - 2.7e-58 195.9 0.0 3.4e-58 195.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin AMP-binding PF00501.28 KXH49642.1 - 6.8e-91 305.0 0.1 8.4e-91 304.7 0.1 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXH49642.1 - 3.5e-12 47.1 0.1 7.6e-12 46.0 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain SAGA-Tad1 PF12767.7 KXH49643.1 - 4.1e-60 203.4 0.0 5.3e-60 203.1 0.0 1.1 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit GCP_C_terminal PF04130.13 KXH49644.1 - 1.1e-100 337.2 0.1 1.6e-100 336.5 0.1 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 KXH49644.1 - 2.8e-84 283.3 0.0 9.5e-84 281.6 0.0 1.8 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal Pkinase PF00069.25 KXH49645.1 - 1.9e-42 145.5 0.0 3.7e-40 138.0 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXH49645.1 - 1.3e-22 80.3 0.0 3.1e-22 79.1 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Abhydrolase_1 PF00561.20 KXH49650.1 - 6.8e-24 84.9 0.0 4.4e-21 75.7 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 KXH49650.1 - 4.9e-18 65.1 0.0 1.2e-17 63.9 0.0 1.7 1 0 0 1 1 1 1 TAP-like protein NmrA PF05368.13 KXH49651.1 - 3.7e-11 43.0 0.0 8.8e-11 41.8 0.0 1.6 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.6 KXH49651.1 - 0.0025 17.7 0.0 0.0056 16.6 0.0 1.6 1 1 0 1 1 1 1 NAD(P)H-binding Pyridoxal_deC PF00282.19 KXH49652.1 - 2.5e-18 66.0 0.0 8.3e-09 34.6 0.0 3.2 3 0 0 3 3 3 3 Pyridoxal-dependent decarboxylase conserved domain PMG PF05287.12 KXH49652.1 - 2.1e-07 31.2 7.7 4e-07 30.2 7.7 1.4 1 0 0 1 1 1 1 PMG protein RicinB_lectin_2 PF14200.6 KXH49654.1 - 9.6e-06 26.2 2.2 0.00015 22.4 0.2 2.4 1 1 2 3 3 3 3 Ricin-type beta-trefoil lectin domain-like Adeno_E3_CR2 PF02439.15 KXH49654.1 - 0.0048 16.6 1.4 0.011 15.5 1.4 1.6 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 EphA2_TM PF14575.6 KXH49654.1 - 0.016 16.0 0.0 0.047 14.6 0.0 1.8 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Mid2 PF04478.12 KXH49654.1 - 0.019 14.8 0.0 0.039 13.8 0.0 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Rax2 PF12768.7 KXH49654.1 - 0.045 13.2 0.0 0.077 12.4 0.0 1.3 1 0 0 1 1 1 0 Cortical protein marker for cell polarity UL45 PF05473.12 KXH49654.1 - 0.062 12.9 1.3 0.28 10.8 0.1 2.4 3 0 0 3 3 3 0 UL45 protein, carbohydrate-binding C-type lectin-like Syndecan PF01034.20 KXH49654.1 - 0.12 12.3 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Syndecan domain MFS_1 PF07690.16 KXH49655.1 - 4.7e-18 65.2 25.6 6e-18 64.9 25.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH49655.1 - 4.1e-07 29.2 17.3 2.2e-06 26.8 17.3 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter Phage_holin_5_2 PF16079.5 KXH49655.1 - 2.5 8.5 8.7 2.6 8.5 0.0 3.1 3 1 0 3 3 3 0 Phage holin family Hol44, in holin superfamily V DSPc PF00782.20 KXH49656.1 - 9.6e-09 35.2 0.0 1.9e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KXH49656.1 - 0.00015 21.4 0.0 0.00028 20.5 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 KXH49656.1 - 0.042 13.8 0.0 0.069 13.1 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family UPF0121 PF03661.13 KXH49657.1 - 2.4e-28 99.1 6.0 3.2e-28 98.7 6.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) Glyco_transf_22 PF03901.17 KXH49658.1 - 2e-74 251.3 12.2 5.8e-74 249.8 12.2 1.6 1 1 0 1 1 1 1 Alg9-like mannosyltransferase family DUF4321 PF14209.6 KXH49658.1 - 0.26 11.1 0.1 0.26 11.1 0.1 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4321) AA_permease PF00324.21 KXH49659.1 - 2.6e-129 432.0 35.7 2.4e-128 428.8 35.7 1.9 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KXH49659.1 - 9.2e-49 166.4 33.7 1.2e-48 166.0 33.7 1.0 1 0 0 1 1 1 1 Amino acid permease Pro_dh PF01619.18 KXH49660.1 - 5.7e-61 206.6 0.0 6.8e-61 206.4 0.0 1.1 1 0 0 1 1 1 1 Proline dehydrogenase AP_endonuc_2 PF01261.24 KXH49660.1 - 0.015 14.7 0.0 0.041 13.3 0.0 1.7 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel PEP_mutase PF13714.6 KXH49660.1 - 0.043 13.3 0.0 0.38 10.2 0.0 2.0 2 0 0 2 2 2 0 Phosphoenolpyruvate phosphomutase Fungal_lectin PF07938.12 KXH49661.1 - 0.0014 18.1 0.0 0.004 16.6 0.0 1.7 2 0 0 2 2 2 1 Fungal fucose-specific lectin TPR_19 PF14559.6 KXH49662.1 - 8.1e-05 23.1 5.7 0.061 13.8 0.4 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KXH49662.1 - 0.00015 22.0 10.4 0.012 15.9 2.2 4.1 3 1 3 6 6 6 3 Tetratricopeptide repeat PPR PF01535.20 KXH49662.1 - 0.15 12.4 0.5 15 6.1 0.0 3.3 3 1 0 3 3 3 0 PPR repeat TPR_4 PF07721.14 KXH49662.1 - 0.53 11.1 3.5 18 6.3 0.1 3.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 KXH49662.1 - 4 8.5 9.2 14 6.8 0.1 4.6 5 1 1 6 6 6 0 Tetratricopeptide repeat T4BSS_DotI_IcmL PF11393.8 KXH49663.1 - 0.11 12.0 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Type-IV b secretion system, inner-membrane complex component MFS_1 PF07690.16 KXH49664.1 - 3.1e-41 141.5 28.2 3.1e-41 141.5 28.2 1.5 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH49664.1 - 7.8e-11 41.5 1.4 7.8e-11 41.5 1.4 1.8 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KXH49664.1 - 4.1e-05 22.2 0.3 5.9e-05 21.7 0.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF4179 PF13786.6 KXH49664.1 - 0.22 12.0 3.0 22 5.6 0.1 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4179) CCDC106 PF15794.5 KXH49664.1 - 1.2 8.8 7.5 1.8 8.2 7.5 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 La PF05383.17 KXH49665.1 - 3.2e-20 71.9 0.0 5.9e-20 71.1 0.0 1.5 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 KXH49665.1 - 3.1e-11 42.9 0.1 6e-11 42.0 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) S4 PF01479.25 KXH49666.1 - 1.8e-13 50.0 0.0 5.8e-13 48.3 0.0 1.9 2 0 0 2 2 2 1 S4 domain S4_2 PF13275.6 KXH49666.1 - 0.0031 17.3 0.0 0.0061 16.3 0.0 1.4 1 0 0 1 1 1 1 S4 domain DUF4011 PF13195.6 KXH49666.1 - 0.33 10.8 2.8 1.4 8.8 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4011) SPOUT_MTase PF02590.17 KXH49666.1 - 7.4 6.5 6.3 4.3 7.3 1.2 2.3 2 0 0 2 2 2 0 Predicted SPOUT methyltransferase Septin PF00735.18 KXH49667.1 - 2.8e-119 397.6 0.1 2.8e-119 397.6 0.1 1.7 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 KXH49667.1 - 2.4e-08 34.1 1.3 4.1e-08 33.3 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KXH49667.1 - 8.8e-07 28.6 1.2 0.00029 20.5 0.0 3.0 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KXH49667.1 - 2e-05 24.6 2.7 0.0029 17.5 1.1 3.3 2 1 0 2 2 2 1 RsgA GTPase ABC_tran PF00005.27 KXH49667.1 - 0.00016 22.2 2.5 0.021 15.3 0.0 2.6 3 0 0 3 3 3 1 ABC transporter AIG1 PF04548.16 KXH49667.1 - 0.00083 18.7 1.5 0.0022 17.4 0.0 2.2 2 0 0 2 2 2 1 AIG1 family Roc PF08477.13 KXH49667.1 - 0.0014 18.8 0.0 0.0032 17.7 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 KXH49667.1 - 0.0017 18.6 0.8 0.011 16.0 0.0 2.6 2 2 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KXH49667.1 - 0.0022 18.4 0.2 0.0052 17.2 0.0 1.7 2 0 0 2 2 1 1 AAA ATPase domain Ras PF00071.22 KXH49667.1 - 0.0054 16.3 0.1 0.04 13.5 0.0 2.3 2 0 0 2 2 2 1 Ras family AAA_29 PF13555.6 KXH49667.1 - 0.014 15.2 0.0 0.025 14.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Caldesmon PF02029.15 KXH49667.1 - 0.044 12.6 17.6 0.066 12.0 17.6 1.2 1 0 0 1 1 1 0 Caldesmon FtsK_SpoIIIE PF01580.18 KXH49667.1 - 0.047 13.0 0.0 0.12 11.7 0.0 1.7 1 0 0 1 1 1 0 FtsK/SpoIIIE family RNA_helicase PF00910.22 KXH49667.1 - 0.052 13.9 0.6 0.58 10.6 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_24 PF13479.6 KXH49667.1 - 0.065 13.0 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 KXH49667.1 - 0.075 13.1 8.9 0.85 9.7 0.0 3.7 4 1 0 4 4 3 0 Dynamin family AAA_7 PF12775.7 KXH49667.1 - 0.093 12.2 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region ATP_bind_1 PF03029.17 KXH49667.1 - 0.12 12.1 2.2 7.8 6.2 0.0 3.2 3 1 0 3 3 3 0 Conserved hypothetical ATP binding protein Exonuc_VII_L PF02601.15 KXH49667.1 - 0.17 11.4 6.2 0.26 10.8 6.2 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit AAA_5 PF07728.14 KXH49667.1 - 0.19 11.7 1.1 3 7.8 0.0 2.8 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) DUF87 PF01935.17 KXH49667.1 - 2.9 7.9 7.1 4.5 7.3 0.0 2.6 3 0 0 3 3 3 0 Helicase HerA, central domain Atg14 PF10186.9 KXH49667.1 - 3.2 6.8 8.0 5.2 6.0 8.0 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 UPF0242 PF06785.11 KXH49667.1 - 10 6.2 14.1 17 5.4 14.1 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus PLA2_B PF01735.18 KXH49668.1 - 1.6e-27 96.1 0.0 4e-27 94.8 0.0 1.6 1 1 0 1 1 1 1 Lysophospholipase catalytic domain Ribonucleas_3_3 PF14622.6 KXH49669.1 - 9.8e-05 22.5 0.0 0.081 13.1 0.0 2.4 2 0 0 2 2 2 2 Ribonuclease-III-like dsrm PF00035.26 KXH49669.1 - 0.036 14.8 0.0 0.071 13.8 0.0 1.5 1 0 0 1 1 1 0 Double-stranded RNA binding motif Ribonuclease_3 PF00636.26 KXH49669.1 - 0.12 13.0 0.0 0.54 10.9 0.0 2.1 1 1 0 1 1 1 0 Ribonuclease III domain SH3_9 PF14604.6 KXH49671.1 - 1.3e-10 40.9 0.0 2.1e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KXH49671.1 - 3.4e-06 26.6 0.0 5.5e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KXH49671.1 - 0.00013 21.6 0.0 0.00022 20.8 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain Glycophorin_A PF01102.18 KXH49671.1 - 0.0088 16.3 1.8 0.012 15.9 0.3 2.0 1 1 0 1 1 1 1 Glycophorin A DUF5305 PF17231.2 KXH49671.1 - 0.021 14.2 0.2 0.041 13.3 0.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5305) RIFIN PF02009.16 KXH49671.1 - 0.031 14.2 1.2 0.052 13.4 1.2 1.3 1 0 0 1 1 1 0 Rifin SKG6 PF08693.10 KXH49671.1 - 0.045 13.2 0.0 0.045 13.2 0.0 3.1 3 0 0 3 3 3 0 Transmembrane alpha-helix domain Amnionless PF14828.6 KXH49671.1 - 0.066 12.0 0.1 0.094 11.5 0.1 1.1 1 0 0 1 1 1 0 Amnionless ATG22 PF11700.8 KXH49671.1 - 0.068 11.8 0.2 0.096 11.3 0.2 1.1 1 0 0 1 1 1 0 Vacuole effluxer Atg22 like ABC2_membrane_3 PF12698.7 KXH49671.1 - 0.13 11.4 0.2 0.19 10.8 0.2 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein Stevor PF17410.2 KXH49671.1 - 0.16 11.5 0.1 0.27 10.8 0.1 1.4 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame CD34_antigen PF06365.12 KXH49671.1 - 0.22 11.1 0.0 0.38 10.3 0.0 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family Syndecan PF01034.20 KXH49671.1 - 0.24 11.3 0.0 0.49 10.3 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain TNFR_16_TM PF18422.1 KXH49671.1 - 0.39 10.7 0.8 0.57 10.2 0.8 1.2 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain Gar1 PF04410.14 KXH49672.1 - 1.5e-46 157.9 0.4 2.9e-46 157.1 0.4 1.4 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region BIRC6 PF12356.8 KXH49672.1 - 0.16 11.4 0.4 7.4 6.0 0.2 2.3 2 0 0 2 2 2 0 Baculoviral IAP repeat-containing protein 6 Cwf_Cwc_15 PF04889.12 KXH49672.1 - 1.2 8.8 10.7 0.68 9.6 2.7 2.4 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein SUIM_assoc PF16619.5 KXH49672.1 - 5.7 7.1 0.0 5.7 7.1 0.0 5.0 4 2 0 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 Fungal_trans PF04082.18 KXH49673.1 - 1.3e-12 47.3 0.1 2.4e-12 46.4 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain FYVE_2 PF02318.16 KXH49673.1 - 0.13 12.5 3.0 0.37 11.0 3.0 1.8 1 0 0 1 1 1 0 FYVE-type zinc finger RTA1 PF04479.13 KXH49674.1 - 1.3e-48 165.3 7.6 1.3e-48 165.3 7.6 2.1 2 1 0 2 2 2 1 RTA1 like protein Abhydrolase_1 PF00561.20 KXH49675.1 - 4.3e-21 75.7 0.0 2e-17 63.7 0.0 2.4 2 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 KXH49675.1 - 1.4e-15 57.2 0.0 2.5e-15 56.5 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Cyclin_N PF00134.23 KXH49677.1 - 9.1e-08 31.9 0.1 1.8e-07 31.0 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Yos1 PF08571.10 KXH49677.1 - 0.068 13.4 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 Yos1-like Palm_thioest PF02089.15 KXH49678.1 - 3e-78 263.0 0.0 3.7e-78 262.7 0.0 1.1 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF915 PF06028.11 KXH49678.1 - 0.0039 16.5 0.0 0.054 12.8 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) Ribosomal_L1 PF00687.21 KXH49679.1 - 1.4e-66 224.1 1.0 1.4e-66 224.1 1.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L1p/L10e family DUF4407 PF14362.6 KXH49682.1 - 2.8 7.2 4.6 0.59 9.4 0.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) zf-RING_2 PF13639.6 KXH49683.1 - 1.5e-08 34.8 9.1 3e-08 33.9 9.1 1.5 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.8 KXH49683.1 - 1.2e-05 25.4 8.4 3.3e-05 24.0 8.4 1.8 1 1 0 1 1 1 1 FANCL C-terminal domain zf-rbx1 PF12678.7 KXH49683.1 - 0.00022 21.4 7.3 0.00052 20.2 7.3 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KXH49683.1 - 0.00028 20.9 2.4 0.00077 19.5 2.4 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 KXH49683.1 - 0.0016 18.3 9.7 0.0032 17.3 9.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.7 KXH49683.1 - 0.0023 18.0 7.8 0.0049 17.0 7.8 1.6 1 0 0 1 1 1 1 RING-variant domain C1_1 PF00130.22 KXH49683.1 - 0.0039 17.1 2.8 0.0039 17.1 2.8 1.8 1 1 1 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Zn_ribbon_17 PF17120.5 KXH49683.1 - 0.021 14.4 5.2 0.042 13.5 5.2 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 KXH49683.1 - 0.028 14.3 5.8 0.052 13.4 5.8 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXH49683.1 - 0.045 13.6 8.1 0.087 12.7 8.1 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.11 KXH49683.1 - 0.081 13.2 8.0 0.16 12.3 8.0 1.5 1 0 0 1 1 1 0 RING-like domain zf-RING_9 PF13901.6 KXH49683.1 - 0.47 10.4 6.3 1.1 9.2 6.3 1.6 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon Prok-RING_4 PF14447.6 KXH49683.1 - 0.65 9.9 6.7 1.9 8.4 6.8 1.8 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 PHD PF00628.29 KXH49683.1 - 2.6 8.0 7.1 4.8 7.2 7.1 1.5 1 0 0 1 1 1 0 PHD-finger zf-RING_5 PF14634.6 KXH49683.1 - 6.4 6.8 8.8 12 6.0 8.8 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_4 PF14570.6 KXH49683.1 - 7.2 6.5 7.7 2.3e+02 1.7 7.7 2.4 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Pkinase PF00069.25 KXH49684.1 - 1.8e-36 125.9 0.0 2.8e-36 125.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXH49684.1 - 1.6e-07 30.9 0.0 2.5e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXH49684.1 - 0.006 16.5 0.0 1.1 9.2 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family KIX_2 PF16987.5 KXH49684.1 - 0.007 16.3 0.2 0.017 15.1 0.1 1.6 2 0 0 2 2 2 1 KIX domain muHD PF10291.9 KXH49685.1 - 2.9e-72 243.3 0.0 4.3e-72 242.7 0.0 1.3 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.23 KXH49685.1 - 6.8e-07 29.5 0.3 2.1e-06 27.9 0.0 2.0 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain LON_substr_bdg PF02190.16 KXH49685.1 - 0.079 12.8 0.3 0.16 11.9 0.3 1.5 1 0 0 1 1 1 0 ATP-dependent protease La (LON) substrate-binding domain DUF3584 PF12128.8 KXH49685.1 - 0.16 9.4 14.4 0.25 8.8 14.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Muted PF14942.6 KXH49685.1 - 0.76 10.1 8.1 0.62 10.4 4.9 2.4 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein FUSC PF04632.12 KXH49685.1 - 9.7 4.6 8.7 1.6 7.1 4.4 1.9 2 0 0 2 2 2 0 Fusaric acid resistance protein family MAD PF05557.13 KXH49686.1 - 1.2e-64 218.9 59.4 1.1e-63 215.7 59.4 1.9 1 1 0 1 1 1 1 Mitotic checkpoint protein Tam41_Mmp37 PF09139.11 KXH49687.1 - 1.7e-126 422.1 0.0 2e-126 421.8 0.0 1.1 1 0 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial Corona_S2 PF01601.16 KXH49688.1 - 0.36 9.3 0.5 0.53 8.7 0.5 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein Bac_rhamnosid6H PF17389.2 KXH49689.1 - 8.2e-18 64.7 0.2 2.6e-16 59.8 0.3 2.1 2 0 0 2 2 2 2 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Trehalase PF01204.18 KXH49689.1 - 0.047 12.5 0.0 0.071 11.9 0.0 1.2 1 0 0 1 1 1 0 Trehalase Pertactin PF03212.14 KXH49690.1 - 0.11 12.4 0.2 0.54 10.2 0.3 2.1 2 0 0 2 2 2 0 Pertactin Fungal_trans PF04082.18 KXH49691.1 - 2.3e-07 30.1 0.2 4.2e-07 29.3 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Peptidase_S10 PF00450.22 KXH49692.1 - 4e-89 299.9 0.0 4.8e-89 299.7 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Glyco_hydro_127 PF07944.12 KXH49693.1 - 6.1e-17 61.3 0.0 4.3e-15 55.2 0.0 2.3 1 1 1 2 2 2 2 Beta-L-arabinofuranosidase, GH127 MFS_1 PF07690.16 KXH49695.1 - 1.3e-37 129.5 34.8 2.1e-37 128.9 34.8 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KXH49695.1 - 7.1e-07 28.0 9.3 7.1e-07 28.0 9.3 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Glyco_tranf_2_3 PF13641.6 KXH49696.1 - 9e-16 58.5 0.1 1.1e-15 58.1 0.1 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KXH49696.1 - 3.8e-07 30.1 0.0 5.7e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 KXH49696.1 - 0.00081 18.9 0.1 0.23 10.9 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 21 Carn_acyltransf PF00755.20 KXH49697.1 - 8.1e-108 361.6 0.0 2.1e-107 360.2 0.0 1.6 2 0 0 2 2 2 1 Choline/Carnitine o-acyltransferase ketoacyl-synt PF00109.26 KXH49697.1 - 1.7e-74 250.6 0.0 4.2e-74 249.3 0.0 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 KXH49697.1 - 9e-56 189.7 2.1 1.4e-55 189.1 2.1 1.2 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.10 KXH49697.1 - 1.1e-47 162.3 0.4 4.4e-47 160.3 0.0 2.2 3 0 0 3 3 3 1 KR domain Ketoacyl-synt_C PF02801.22 KXH49697.1 - 1.4e-37 128.3 0.2 6.5e-37 126.1 0.1 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KXH49697.1 - 1.3e-17 64.2 1.2 2.9e-16 59.9 1.2 2.8 1 1 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 KXH49697.1 - 7.5e-10 38.6 0.1 8.4e-09 35.2 0.0 2.6 2 0 0 2 2 2 1 short chain dehydrogenase ADH_zinc_N_2 PF13602.6 KXH49697.1 - 5.3e-07 30.7 0.0 5.2e-06 27.6 0.0 2.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase PP-binding PF00550.25 KXH49697.1 - 6.1e-07 29.7 0.1 1.7e-06 28.2 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site PS-DH PF14765.6 KXH49697.1 - 1.6e-05 24.3 0.2 3.2e-05 23.3 0.2 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase SAT PF16073.5 KXH49697.1 - 0.0059 16.4 1.2 0.012 15.3 1.2 1.5 1 0 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis DUF982 PF06169.12 KXH49697.1 - 0.015 15.3 0.4 0.054 13.5 0.4 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF982) Thiolase_N PF00108.23 KXH49697.1 - 0.034 13.5 0.0 0.072 12.4 0.0 1.4 1 0 0 1 1 1 0 Thiolase, N-terminal domain Fungal_trans PF04082.18 KXH49698.1 - 4.5e-26 91.5 0.0 6.8e-26 90.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH49698.1 - 5.1e-08 32.9 13.8 1e-07 32.0 13.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyoxalase PF00903.25 KXH49699.1 - 7.7e-14 52.0 0.0 1.1e-13 51.5 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily TFIIB PF00382.19 KXH49700.1 - 0.058 13.4 0.0 0.2 11.7 0.0 1.8 2 0 0 2 2 2 0 Transcription factor TFIIB repeat adh_short PF00106.25 KXH49701.1 - 2.9e-24 85.6 0.0 2.1e-11 43.7 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXH49701.1 - 2.3e-14 53.5 0.0 1.5e-07 31.2 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH49701.1 - 0.012 15.5 0.1 0.048 13.6 0.0 1.8 2 0 0 2 2 2 0 KR domain NAD_binding_10 PF13460.6 KXH49701.1 - 0.03 14.2 0.1 0.071 13.0 0.1 1.6 1 0 0 1 1 1 0 NAD(P)H-binding MlaD PF02470.20 KXH49701.1 - 0.086 13.2 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 MlaD protein Amidase PF01425.21 KXH49702.1 - 1.5e-05 24.2 0.0 4.4e-05 22.6 0.0 1.7 2 0 0 2 2 2 1 Amidase Amino_oxidase PF01593.24 KXH49703.1 - 1.3e-35 123.6 0.2 1.7e-35 123.2 0.2 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KXH49703.1 - 1.5e-06 28.3 0.0 4.4e-06 26.8 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXH49703.1 - 0.00041 20.1 0.0 0.00087 19.0 0.0 1.7 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXH49703.1 - 0.0029 16.9 0.0 0.011 15.0 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KXH49703.1 - 0.011 15.0 0.1 0.021 14.1 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 KXH49703.1 - 0.045 13.0 0.0 0.076 12.2 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF3866 PF12982.7 KXH49703.1 - 0.078 12.1 0.2 0.15 11.2 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3866) MFS_1 PF07690.16 KXH49704.1 - 2.9e-28 98.8 46.4 2.2e-15 56.5 10.8 2.6 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.13 KXH49704.1 - 1.6e-11 43.3 25.0 1.6e-10 40.1 25.0 2.0 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KXH49704.1 - 7.3e-07 28.4 7.5 7.3e-07 28.4 7.5 3.4 2 2 2 4 4 4 2 Sugar (and other) transporter DUF1674 PF07896.12 KXH49704.1 - 0.37 11.3 0.9 0.54 10.8 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1674) PALP PF00291.25 KXH49705.1 - 5.7e-35 121.2 0.0 8.8e-35 120.5 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Rhodanese PF00581.20 KXH49705.1 - 5.9e-05 23.5 0.0 0.00031 21.2 0.0 2.0 2 0 0 2 2 2 1 Rhodanese-like domain MFS_1 PF07690.16 KXH49706.1 - 4.3e-24 85.1 38.2 7.5e-23 81.0 35.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TraL PF07178.11 KXH49706.1 - 1.7 9.2 6.2 0.79 10.2 0.7 3.2 3 0 0 3 3 3 0 TraL protein Sterol-sensing PF12349.8 KXH49706.1 - 6.3 6.6 8.0 9.5 6.0 0.5 2.6 2 0 0 2 2 2 0 Sterol-sensing domain of SREBP cleavage-activation FAD_binding_3 PF01494.19 KXH49707.1 - 2.1e-60 204.8 0.0 2.9e-29 102.4 0.0 2.2 1 1 1 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 KXH49707.1 - 0.00082 18.7 0.0 0.46 9.7 0.0 3.6 2 1 2 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXH49707.1 - 0.0037 17.8 0.0 0.011 16.2 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXH49707.1 - 0.065 13.5 0.0 0.28 11.5 0.0 2.1 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DUF1314 PF07013.11 KXH49707.1 - 0.087 12.7 0.2 0.32 10.8 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1314) p450 PF00067.22 KXH49708.1 - 6.5e-61 206.5 0.0 9e-61 206.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Nitroreductase PF00881.24 KXH49709.1 - 2.8e-13 50.3 0.1 3.5e-13 50.0 0.1 1.1 1 0 0 1 1 1 1 Nitroreductase family MFS_1 PF07690.16 KXH49710.1 - 2.3e-42 145.2 40.0 2.3e-42 145.2 40.0 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH49711.1 - 2.6e-92 310.1 22.3 2.9e-92 309.9 22.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH49711.1 - 1.1e-19 70.6 33.0 4.5e-14 52.1 15.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MLTD_N PF06474.12 KXH49711.1 - 0.07 13.3 0.5 0.21 11.8 0.5 1.8 1 0 0 1 1 1 0 MltD lipid attachment motif Asp4 PF16996.5 KXH49711.1 - 0.46 10.3 0.0 0.46 10.3 0.0 2.2 2 0 0 2 2 2 0 Accessory secretory protein Sec Asp4 MFS_4 PF06779.14 KXH49711.1 - 1.8 7.8 22.2 0.039 13.2 9.7 3.0 2 1 1 3 3 3 0 Uncharacterised MFS-type transporter YbfB ADH_N PF08240.12 KXH49712.1 - 5.9e-19 68.0 0.1 1.2e-18 67.0 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXH49712.1 - 4.3e-12 46.1 1.8 5.2e-12 45.9 0.1 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXH49712.1 - 5.9e-06 27.4 0.1 4.3e-05 24.6 0.0 2.1 1 1 0 2 2 2 1 Zinc-binding dehydrogenase Fungal_trans PF04082.18 KXH49713.1 - 3.4e-28 98.4 0.0 7.8e-28 97.2 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH49713.1 - 3.8e-09 36.5 7.6 6.2e-09 35.8 7.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4306 PF14154.6 KXH49713.1 - 0.14 12.4 0.1 0.25 11.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4306) Fungal_trans PF04082.18 KXH49714.1 - 1e-25 90.3 0.2 1.6e-25 89.6 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH49714.1 - 1.1e-07 31.9 7.7 1.9e-07 31.1 7.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GATA PF00320.27 KXH49867.1 - 1.4e-16 59.8 2.3 2.8e-16 58.8 2.3 1.5 1 0 0 1 1 1 1 GATA zinc finger Kelch_4 PF13418.6 KXH49868.1 - 2.2e-34 117.2 7.2 6.6e-07 29.2 0.9 6.5 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_1 PF01344.25 KXH49868.1 - 4e-29 99.9 7.3 3.7e-13 48.8 0.7 6.7 6 0 0 6 6 6 5 Kelch motif Kelch_5 PF13854.6 KXH49868.1 - 1.7e-27 94.9 12.4 2.3e-08 33.8 0.3 6.8 7 0 0 7 7 7 5 Kelch motif Kelch_3 PF13415.6 KXH49868.1 - 1.5e-26 92.1 7.9 6.5e-08 32.7 0.2 6.1 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_6 PF13964.6 KXH49868.1 - 3.2e-26 90.7 7.2 7.3e-11 42.0 0.8 6.5 5 1 1 6 6 6 6 Kelch motif Kelch_2 PF07646.15 KXH49868.1 - 1.9e-19 68.8 8.4 7.2e-07 28.9 0.3 6.6 6 0 0 6 6 6 5 Kelch motif Filament PF00038.21 KXH49868.1 - 0.002 17.8 28.6 0.002 17.8 28.6 3.9 3 2 1 4 4 4 1 Intermediate filament protein Raptor_N PF14538.6 KXH49869.1 - 3.6e-65 218.4 0.0 6.9e-65 217.5 0.0 1.5 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.32 KXH49869.1 - 2.4e-07 31.4 0.7 4.5 8.3 0.0 6.1 5 0 0 5 5 5 2 WD domain, G-beta repeat HEAT PF02985.22 KXH49869.1 - 0.0013 18.8 0.9 29 5.3 0.0 5.1 6 0 0 6 6 6 0 HEAT repeat Atx10homo_assoc PF09759.9 KXH49869.1 - 0.0072 16.3 0.3 0.014 15.4 0.3 1.4 1 0 0 1 1 1 1 Spinocerebellar ataxia type 10 protein domain BBS2_Mid PF14783.6 KXH49869.1 - 0.02 14.9 0.0 7.3 6.7 0.0 2.6 1 1 1 2 2 2 0 Ciliary BBSome complex subunit 2, middle region HEAT_2 PF13646.6 KXH49869.1 - 0.028 14.8 0.0 1.7 9.1 0.0 3.2 2 1 1 3 3 3 0 HEAT repeats Cnd1 PF12717.7 KXH49869.1 - 0.21 11.6 0.1 3.2 7.8 0.0 2.5 2 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Ank_5 PF13857.6 KXH49870.1 - 4.3e-17 62.0 2.3 1.5e-07 31.5 0.1 3.7 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXH49870.1 - 4.4e-14 52.8 0.0 4.4e-09 36.8 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXH49870.1 - 2.9e-11 42.5 0.5 0.093 13.3 0.0 4.8 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.6 KXH49870.1 - 3.1e-10 40.4 0.2 3.8e-06 27.3 0.0 3.8 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 KXH49870.1 - 4.6e-06 26.8 5.2 0.99 10.0 0.1 4.7 5 0 0 5 5 5 3 Ankyrin repeat Ank_2 PF12796.7 KXH49871.1 - 3.8e-33 113.9 0.0 5.4e-09 36.5 0.0 7.4 5 1 3 8 8 8 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXH49871.1 - 1.1e-22 80.1 1.6 0.00066 20.2 0.1 8.5 6 2 3 9 9 9 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXH49871.1 - 2.8e-22 76.4 0.0 0.019 15.4 0.0 9.9 10 0 0 10 10 10 4 Ankyrin repeat Ank_5 PF13857.6 KXH49871.1 - 2.1e-18 66.1 0.3 0.00017 21.8 0.0 7.2 6 1 1 7 7 7 2 Ankyrin repeats (many copies) Ank PF00023.30 KXH49871.1 - 9e-17 60.7 2.6 0.16 12.5 0.0 10.4 11 0 0 11 11 11 2 Ankyrin repeat AAA_22 PF13401.6 KXH49871.1 - 1.6e-09 38.2 1.4 4.4e-08 33.5 0.1 2.7 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KXH49871.1 - 2.8e-06 27.4 1.1 5.5e-06 26.4 0.0 2.1 3 0 0 3 3 3 1 NACHT domain AAA_16 PF13191.6 KXH49871.1 - 7.2e-06 26.5 0.1 4.9e-05 23.8 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain RPAP1_N PF08621.10 KXH49871.1 - 0.11 12.3 0.5 1 9.2 0.0 2.9 3 0 0 3 3 3 0 RPAP1-like, N-terminal dCache_2 PF08269.11 KXH49871.1 - 1.4 8.0 4.5 2.5 7.2 0.7 2.3 2 0 0 2 2 2 0 Cache domain DLH PF01738.18 KXH49872.1 - 1.6e-18 67.1 0.0 1.9e-18 66.8 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family NUDIX PF00293.28 KXH49873.1 - 9.5e-11 41.9 0.1 5.2e-10 39.5 0.1 1.9 1 1 0 1 1 1 1 NUDIX domain Carboxyl_trans PF01039.22 KXH49874.1 - 1.6e-138 462.4 0.1 2.2e-138 462.0 0.1 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain Acyl-CoA_dh_1 PF00441.24 KXH49875.1 - 2.3e-40 138.3 0.8 3.9e-40 137.5 0.8 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KXH49875.1 - 6.6e-31 107.3 0.1 1.4e-30 106.3 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KXH49875.1 - 1.6e-27 95.5 0.4 3.2e-27 94.6 0.4 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KXH49875.1 - 1.1e-13 51.7 0.3 2e-13 50.8 0.1 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 KXH49875.1 - 6.5e-05 22.7 0.1 0.00017 21.4 0.1 1.6 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal Helo_like_N PF17111.5 KXH49876.1 - 4.3e-11 42.6 3.0 5.6e-11 42.2 2.6 1.3 1 1 0 1 1 1 1 Fungal N-terminal domain of STAND proteins SesA PF17107.5 KXH49876.1 - 3.1e-05 24.2 5.1 0.00012 22.3 1.4 2.2 1 1 1 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases PB1 PF00564.24 KXH49876.1 - 0.0038 17.1 0.1 0.0085 16.0 0.1 1.6 1 0 0 1 1 1 1 PB1 domain HMD PF03201.16 KXH49876.1 - 0.013 15.8 0.5 0.029 14.6 0.5 1.7 1 0 0 1 1 1 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase CHIP_TPR_N PF18391.1 KXH49876.1 - 0.04 14.7 2.2 0.064 14.0 0.5 2.0 2 0 0 2 2 2 0 CHIP N-terminal tetratricopeptide repeat domain Spt5-NGN PF03439.13 KXH49876.1 - 0.12 12.3 0.1 0.34 10.8 0.1 1.7 1 0 0 1 1 1 0 Early transcription elongation factor of RNA pol II, NGN section ABC_tran_CTD PF16326.5 KXH49876.1 - 0.81 10.0 3.9 9.1 6.6 0.1 2.4 2 0 0 2 2 2 0 ABC transporter C-terminal domain AAA_22 PF13401.6 KXH49877.1 - 0.00092 19.5 0.0 0.0016 18.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 KXH49877.1 - 0.0051 16.7 0.0 0.0084 16.0 0.0 1.4 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.22 KXH49877.1 - 0.016 14.4 0.0 0.025 13.7 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_16 PF13191.6 KXH49877.1 - 0.033 14.6 0.0 0.11 12.9 0.0 1.9 1 1 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 KXH49877.1 - 0.044 14.2 0.0 0.084 13.3 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 KXH49877.1 - 0.085 13.2 0.0 0.14 12.5 0.0 1.3 1 1 0 1 1 1 0 AAA domain ResIII PF04851.15 KXH49877.1 - 0.097 12.7 0.0 0.22 11.5 0.0 1.6 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Ank_2 PF12796.7 KXH49878.1 - 7.2e-13 48.9 0.6 2.5e-09 37.6 0.0 3.4 3 1 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXH49878.1 - 8e-08 32.0 2.2 0.012 16.0 0.0 5.0 6 0 0 6 6 6 2 Ankyrin repeat Ank PF00023.30 KXH49878.1 - 1.9e-06 28.0 2.0 0.0021 18.4 0.0 4.9 5 0 0 5 5 5 1 Ankyrin repeat Ank_4 PF13637.6 KXH49878.1 - 2.6e-05 24.7 0.0 0.04 14.5 0.0 4.2 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXH49878.1 - 4.2e-05 23.7 1.5 0.03 14.6 0.0 4.4 4 1 1 5 5 5 1 Ankyrin repeats (many copies) adh_short_C2 PF13561.6 KXH49879.1 - 2.7e-51 174.4 0.0 3.9e-51 173.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXH49879.1 - 1.4e-35 122.5 0.0 2.2e-35 121.9 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXH49879.1 - 5.1e-11 42.8 1.2 1.8e-10 41.0 0.1 1.9 2 0 0 2 2 2 1 KR domain GDP_Man_Dehyd PF16363.5 KXH49879.1 - 0.12 11.7 0.0 8 5.7 0.0 2.1 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase DUF1752 PF08550.10 KXH49880.1 - 0.00013 21.8 2.2 0.00026 20.8 2.2 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) CNDH2_C PF16858.5 KXH49882.1 - 0.088 12.7 5.6 0.15 11.9 5.6 1.2 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term ATP-synt_E PF05680.12 KXH49882.1 - 7.7 6.9 10.8 3.4 8.1 3.5 2.5 2 0 0 2 2 2 0 ATP synthase E chain PHD PF00628.29 KXH49883.1 - 1.9e-09 37.3 1.9 4.2e-09 36.2 1.9 1.6 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 KXH49883.1 - 0.0018 17.8 3.1 0.0032 17.0 3.1 1.5 1 0 0 1 1 1 1 PHD-finger UIM PF02809.20 KXH49883.1 - 0.0025 17.6 3.4 0.0071 16.2 3.4 1.8 1 0 0 1 1 1 1 Ubiquitin interaction motif zf-CW PF07496.15 KXH49883.1 - 0.12 12.4 0.9 0.39 10.8 0.9 1.9 1 0 0 1 1 1 0 CW-type Zinc Finger CEBP_ZZ PF16366.5 KXH49883.1 - 0.21 11.9 1.9 0.56 10.5 1.9 1.7 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain MMR_HSR1 PF01926.23 KXH49884.1 - 2.4e-11 43.7 0.0 4.2e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KXH49884.1 - 0.0013 18.3 0.1 0.003 17.1 0.1 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B MeaB PF03308.16 KXH49884.1 - 0.011 14.8 0.1 0.034 13.1 0.1 1.8 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB RsgA_GTPase PF03193.16 KXH49884.1 - 0.014 15.3 1.4 0.077 12.9 1.4 2.0 1 1 0 1 1 1 0 RsgA GTPase Arf PF00025.21 KXH49884.1 - 0.066 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA_18 PF13238.6 KXH49884.1 - 0.089 13.3 0.2 0.34 11.5 0.1 2.0 2 0 0 2 2 2 0 AAA domain IIGP PF05049.13 KXH49884.1 - 0.22 10.5 0.0 0.32 10.0 0.0 1.1 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) HCO3_cotransp PF00955.21 KXH49885.1 - 9.3e-72 242.5 6.5 1.2e-39 136.5 0.0 2.1 1 1 1 2 2 2 2 HCO3- transporter family PAXIP1_C PF15364.6 KXH49898.1 - 4.2 7.7 7.3 12 6.2 0.5 2.6 2 0 0 2 2 2 0 PAXIP1-associated-protein-1 C term PTIP binding protein adh_short PF00106.25 KXH49899.1 - 4.9e-36 124.0 0.0 6.5e-36 123.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXH49899.1 - 1.2e-17 64.3 0.0 1.6e-17 63.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH49899.1 - 2.4e-11 43.9 0.3 1.5e-08 34.7 0.0 2.1 2 0 0 2 2 2 2 KR domain NAD_binding_10 PF13460.6 KXH49899.1 - 9.4e-05 22.4 0.1 0.00014 21.8 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KXH49899.1 - 0.00048 19.7 0.0 0.0015 18.1 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family ADH_zinc_N PF00107.26 KXH49899.1 - 0.0056 16.6 0.0 0.0087 16.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF1776 PF08643.10 KXH49899.1 - 0.006 16.0 1.1 0.0083 15.5 1.1 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Sacchrp_dh_NADP PF03435.18 KXH49899.1 - 0.022 15.0 0.0 0.07 13.4 0.1 1.8 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain GDP_Man_Dehyd PF16363.5 KXH49899.1 - 0.052 12.9 0.0 0.15 11.5 0.0 1.6 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Bap31_Bap29_C PF18035.1 KXH49901.1 - 0.1 12.6 5.3 0.27 11.3 0.5 2.2 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain CemA PF03040.14 KXH49901.1 - 0.1 12.5 0.8 0.13 12.2 0.8 1.1 1 0 0 1 1 1 0 CemA family OmpH PF03938.14 KXH49901.1 - 0.5 10.7 6.4 1.1 9.6 6.5 1.4 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Pro_Al_protease PF02983.14 KXH49902.1 - 2.6e-13 49.8 2.7 2.6e-13 49.8 2.7 1.9 2 0 0 2 2 2 1 Alpha-lytic protease prodomain Trypsin PF00089.26 KXH49902.1 - 5.6e-05 23.1 10.1 0.00018 21.4 10.1 1.7 1 1 0 1 1 1 1 Trypsin Cu-oxidase_3 PF07732.15 KXH49903.1 - 5.4e-41 139.3 2.3 2.6e-40 137.1 0.3 2.9 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KXH49903.1 - 1.8e-31 108.7 6.5 1.6e-28 99.1 0.4 3.7 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 KXH49903.1 - 3e-17 63.2 0.0 1.5e-15 57.7 0.0 2.9 2 1 0 2 2 2 1 Multicopper oxidase Cupredoxin_1 PF13473.6 KXH49903.1 - 0.036 14.2 0.0 0.12 12.5 0.0 1.9 1 1 0 1 1 1 0 Cupredoxin-like domain SGL PF08450.12 KXH49904.1 - 0.0007 19.3 0.0 0.0018 17.9 0.0 1.7 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region FMO-like PF00743.19 KXH49905.1 - 2.9e-89 299.9 0.0 3.6e-89 299.6 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KXH49905.1 - 1.8e-14 53.7 0.0 5.3e-12 45.6 0.0 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXH49905.1 - 7.5e-14 51.6 0.0 2.1e-10 40.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXH49905.1 - 3.3e-12 46.2 0.1 3.9e-08 32.8 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KXH49905.1 - 4.7e-07 29.9 0.1 0.014 15.4 0.0 3.3 3 0 0 3 3 3 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KXH49905.1 - 2.4e-06 27.7 0.0 5.7e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KXH49905.1 - 1.6e-05 25.4 0.0 0.11 13.0 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXH49905.1 - 0.0012 17.7 0.5 0.0024 16.6 0.2 1.6 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.24 KXH49905.1 - 0.0027 17.4 1.5 2.3 7.7 0.0 3.3 3 1 0 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.17 KXH49905.1 - 0.005 16.1 0.1 0.03 13.5 0.1 2.0 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.22 KXH49905.1 - 0.025 13.6 0.0 3.3 6.7 0.0 2.6 3 0 0 3 3 3 0 Glucose inhibited division protein A Shikimate_DH PF01488.20 KXH49905.1 - 0.048 13.7 0.0 13 5.8 0.0 2.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase AlaDh_PNT_C PF01262.21 KXH49905.1 - 0.083 12.2 0.2 0.19 11.0 0.0 1.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 KXH49905.1 - 0.11 11.6 0.0 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.7 KXH49905.1 - 0.17 11.2 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KXH49905.1 - 0.21 10.8 0.2 0.5 9.6 0.1 1.6 2 0 0 2 2 2 0 FAD binding domain adh_short PF00106.25 KXH49906.1 - 2.5e-16 59.7 0.1 1e-11 44.7 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXH49906.1 - 4.1e-10 39.6 0.1 2.2e-07 30.7 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KXH49906.1 - 0.0003 20.3 0.0 0.0004 19.9 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KXH49906.1 - 0.03 14.2 0.0 0.046 13.6 0.0 1.3 1 0 0 1 1 1 0 KR domain Melibiase PF02065.18 KXH49908.1 - 7.6e-147 488.8 0.0 9.4e-147 488.5 0.0 1.1 1 0 0 1 1 1 1 Melibiase Glyco_hydro_36N PF16875.5 KXH49908.1 - 4.7e-80 268.8 0.0 7.1e-80 268.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 36 N-terminal domain Glyco_hydro_36C PF16874.5 KXH49908.1 - 2.9e-23 82.1 0.1 7.3e-23 80.9 0.1 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 36 C-terminal domain GHL10 PF02638.15 KXH49908.1 - 0.00064 18.9 0.1 0.00099 18.3 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase-like 10 FAD_binding_3 PF01494.19 KXH49909.1 - 1.7e-23 83.4 0.0 2.6e-23 82.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 KXH49909.1 - 0.00045 19.4 0.1 0.34 9.9 0.1 2.6 3 0 0 3 3 3 2 Lycopene cyclase protein Amino_oxidase PF01593.24 KXH49909.1 - 0.0057 16.0 0.0 0.17 11.1 0.0 2.4 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 KXH49909.1 - 0.0072 15.6 0.4 0.08 12.2 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXH49909.1 - 0.018 14.6 0.0 0.072 12.7 0.0 1.9 1 1 1 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KXH49909.1 - 0.038 13.2 0.5 0.53 9.5 0.1 2.4 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXH49909.1 - 0.062 13.9 1.0 0.12 13.0 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KXH49909.1 - 0.14 10.9 0.6 14 4.4 0.0 2.8 2 1 0 3 3 3 0 Tryptophan halogenase Aminotran_1_2 PF00155.21 KXH49910.1 - 4.5e-39 134.7 0.0 5.7e-39 134.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Viral_DNA_bi PF02236.17 KXH49910.1 - 0.17 12.0 0.0 0.46 10.7 0.0 1.7 1 0 0 1 1 1 0 Viral DNA-binding protein, all alpha domain DinB PF05163.12 KXH49911.1 - 3.5e-18 66.1 0.7 4.2e-18 65.8 0.7 1.0 1 0 0 1 1 1 1 DinB family DinB_2 PF12867.7 KXH49911.1 - 2.3e-06 28.1 0.3 2.7e-06 27.9 0.3 1.1 1 0 0 1 1 1 1 DinB superfamily HsbA PF12296.8 KXH49967.1 - 1.2e-18 67.6 6.5 2e-18 67.0 6.5 1.3 1 0 0 1 1 1 1 Hydrophobic surface binding protein A Acetyltransf_1 PF00583.25 KXH49968.1 - 4.9e-10 39.7 0.0 6e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXH49968.1 - 3.6e-07 30.5 0.0 5.3e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KXH49968.1 - 2.6e-06 27.4 0.0 4.5e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXH49968.1 - 0.00017 21.5 0.0 0.00032 20.6 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_6 PF13480.7 KXH49968.1 - 0.13 12.4 0.1 0.37 10.9 0.0 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain MMS1_N PF10433.9 KXH49969.1 - 3.6e-116 388.7 0.0 5.9e-116 388.0 0.0 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 KXH49969.1 - 7.7e-67 225.9 0.0 3.5e-65 220.5 0.0 2.3 2 0 0 2 2 2 2 CPSF A subunit region Rieske PF00355.26 KXH49970.1 - 1.7e-10 40.7 0.0 3.1e-10 39.9 0.0 1.4 1 1 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_TM PF02921.14 KXH49970.1 - 3.5e-09 37.0 1.4 1.7e-08 34.8 1.1 2.3 2 1 0 2 2 2 1 Ubiquinol cytochrome reductase transmembrane region HET PF06985.11 KXH49972.1 - 3.1e-32 112.0 0.0 5.8e-32 111.1 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Zip PF02535.22 KXH49972.1 - 3.3 6.8 5.2 5.1 6.2 5.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter CDC45 PF02724.14 KXH49972.1 - 5.2 5.2 6.3 7.9 4.6 6.3 1.2 1 0 0 1 1 1 0 CDC45-like protein Astro_capsid_p PF12226.8 KXH49972.1 - 5.5 6.0 7.5 8.3 5.5 7.5 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein SDA1 PF05285.12 KXH49972.1 - 7 6.0 9.3 11 5.3 9.3 1.2 1 0 0 1 1 1 0 SDA1 WD40 PF00400.32 KXH49973.1 - 1.7e-22 79.3 16.9 2.5e-06 28.1 0.3 6.5 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXH49973.1 - 1.2e-10 41.6 0.0 4.4e-05 23.7 0.1 4.2 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KXH49973.1 - 5.1e-06 25.7 2.3 0.044 12.8 0.2 3.5 1 1 2 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KXH49973.1 - 6.5e-05 21.8 1.5 0.14 10.7 0.7 2.7 1 1 0 2 2 2 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 KXH49973.1 - 0.027 13.0 0.4 15 4.0 0.0 3.0 1 1 2 3 3 3 0 Cytochrome D1 heme domain Ank_4 PF13637.6 KXH49975.1 - 7e-34 115.8 4.4 1.2e-11 44.9 0.0 4.7 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXH49975.1 - 2.4e-29 101.8 0.8 1.8e-10 41.3 0.1 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXH49975.1 - 2.9e-25 85.5 2.0 0.0005 20.3 0.0 5.5 6 0 0 6 6 6 5 Ankyrin repeat Ank PF00023.30 KXH49975.1 - 7.1e-22 76.8 10.5 0.00024 21.4 0.1 6.1 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 KXH49975.1 - 3.2e-10 40.0 6.9 0.0013 19.0 0.1 4.8 1 1 4 5 5 5 5 Ankyrin repeats (many copies) SnoaL_2 PF12680.7 KXH49975.1 - 0.06 14.0 1.1 12 6.6 0.1 2.3 2 0 0 2 2 2 0 SnoaL-like domain Zn_clus PF00172.18 KXH49976.1 - 2.1e-06 27.8 7.2 3.2e-06 27.1 7.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXH49976.1 - 5.2e-06 25.7 1.6 2e-05 23.7 0.1 2.3 3 0 0 3 3 3 1 Fungal specific transcription factor domain RHD_DNA_bind PF00554.22 KXH49976.1 - 0.11 12.5 0.3 0.19 11.6 0.3 1.3 1 0 0 1 1 1 0 Rel homology DNA-binding domain DUF4503 PF14951.6 KXH49976.1 - 0.64 8.4 4.2 1 7.7 4.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4503) NAD_binding_2 PF03446.15 KXH49977.1 - 6e-68 228.0 5.0 2.9e-36 125.0 1.9 2.9 3 0 0 3 3 3 2 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KXH49977.1 - 1.4e-67 225.5 1.6 1.4e-34 119.0 0.1 2.6 2 0 0 2 2 2 2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase SBD_N PF07005.11 KXH49977.1 - 2.5e-59 200.8 0.1 5.7e-59 199.6 0.0 1.7 2 0 0 2 2 2 1 Sugar-binding N-terminal domain NBD_C PF17042.5 KXH49977.1 - 7.2e-44 150.3 1.7 2.2e-43 148.7 1.7 1.9 1 0 0 1 1 1 1 Nucleotide-binding C-terminal domain F420_oxidored PF03807.17 KXH49977.1 - 1e-11 45.3 3.9 7.7e-05 23.2 0.5 4.9 3 2 3 6 6 6 2 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 KXH49977.1 - 1.4e-11 44.1 0.0 9.9e-06 25.0 0.0 2.5 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 KXH49977.1 - 1.6e-06 28.1 1.6 0.00077 19.4 0.5 2.5 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 KXH49977.1 - 0.00034 20.3 1.3 0.066 12.9 0.1 2.8 3 0 0 3 3 3 2 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh PF00984.19 KXH49977.1 - 0.008 16.4 0.6 12 6.2 0.0 3.7 4 1 0 4 4 4 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_N PF03721.14 KXH49977.1 - 0.052 13.1 0.7 3.8 7.0 0.0 3.3 2 1 1 3 3 3 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.15 KXH49977.1 - 0.12 12.8 0.0 2.6 8.5 0.0 2.6 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain DUF1308 PF07000.11 KXH49978.1 - 0.0013 18.7 0.0 0.035 14.0 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1308) CitG PF01874.16 KXH49978.1 - 0.14 11.8 0.0 0.51 9.9 0.0 1.9 2 0 0 2 2 2 0 ATP:dephospho-CoA triphosphoribosyl transferase SnoaL_2 PF12680.7 KXH49979.1 - 0.0058 17.2 0.1 0.0074 16.9 0.1 1.2 1 0 0 1 1 1 1 SnoaL-like domain N2227 PF07942.12 KXH49980.1 - 9.9e-61 205.3 0.0 1.5e-60 204.7 0.0 1.2 1 0 0 1 1 1 1 N2227-like protein Methyltransf_11 PF08241.12 KXH49980.1 - 0.00011 22.8 0.0 0.00036 21.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH49980.1 - 0.00023 21.8 0.0 0.0014 19.3 0.0 2.3 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXH49980.1 - 0.00043 20.2 0.0 0.00088 19.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain NFRKB_winged PF14465.6 KXH49980.1 - 0.0092 16.2 0.0 0.084 13.1 0.0 2.3 2 0 0 2 2 2 1 NFRKB Winged Helix-like Methyltransf_25 PF13649.6 KXH49980.1 - 0.011 16.4 0.0 0.067 13.9 0.0 2.3 1 1 1 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.6 KXH49980.1 - 0.018 14.9 0.0 0.22 11.3 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain Cellulase PF00150.18 KXH49982.1 - 1.1e-31 110.4 0.2 1.6e-31 109.8 0.2 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Zn_clus PF00172.18 KXH49983.1 - 9.8e-08 32.0 7.1 1.9e-07 31.1 7.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXH49983.1 - 8.3e-06 25.0 0.4 1.4e-05 24.3 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sugar_tr PF00083.24 KXH49984.1 - 1e-78 265.2 20.7 1.2e-78 265.0 20.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH49984.1 - 3.5e-17 62.4 29.5 2e-09 36.8 12.3 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily ThaI PF15514.6 KXH49984.1 - 0.11 12.2 0.1 1.1 8.9 0.1 2.1 2 0 0 2 2 2 0 Restriction endonuclease ThaI HAMP PF00672.25 KXH50087.1 - 1.7e-38 130.8 21.0 4.6e-08 33.3 0.4 8.0 7 1 1 8 8 8 6 HAMP domain HATPase_c PF02518.26 KXH50087.1 - 1.2e-30 106.2 0.1 5.3e-30 104.2 0.1 2.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KXH50087.1 - 1.4e-26 92.8 1.0 9.6e-26 90.2 0.3 2.7 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 KXH50087.1 - 2.9e-17 62.5 4.2 7.8e-17 61.1 0.5 3.7 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain Syntaxin_2 PF14523.6 KXH50087.1 - 6.3e-07 29.7 16.5 3.4 8.1 0.2 7.5 2 1 2 6 6 6 3 Syntaxin-like protein DUF4279 PF14106.6 KXH50087.1 - 0.00081 19.6 0.0 36 4.6 0.0 5.6 6 0 0 6 6 5 0 Domain of unknown function (DUF4279) Fib_alpha PF08702.10 KXH50087.1 - 0.0015 18.7 35.1 0.084 13.1 0.8 7.4 7 1 1 8 8 8 2 Fibrinogen alpha/beta chain family DUF948 PF06103.11 KXH50087.1 - 0.002 18.3 45.9 0.33 11.2 1.2 9.4 4 3 2 6 6 6 3 Bacterial protein of unknown function (DUF948) DUF3829 PF12889.7 KXH50087.1 - 0.013 15.0 9.9 1.2 8.5 0.1 4.6 4 2 0 4 4 4 0 Protein of unknown function (DUF3829) DUF1759 PF03564.15 KXH50087.1 - 0.017 15.0 0.3 39 4.1 0.1 4.3 4 0 0 4 4 4 0 Protein of unknown function (DUF1759) HTH_6 PF01418.17 KXH50087.1 - 0.11 12.5 0.0 18 5.4 0.0 3.7 3 0 0 3 3 3 0 Helix-turn-helix domain, rpiR family UBD PF16455.5 KXH50087.1 - 0.29 11.4 1.2 2.9 8.2 0.1 2.9 2 0 0 2 2 2 0 Ubiquitin-binding domain Laminin_II PF06009.12 KXH50087.1 - 0.51 10.3 38.4 0.44 10.6 0.2 7.8 7 1 1 8 8 8 0 Laminin Domain II HAD_2 PF13419.6 KXH50110.1 - 0.00031 20.9 0.0 0.00054 20.1 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Kinesin PF00225.23 KXH50111.1 - 9.4e-108 360.1 0.1 9.4e-108 360.1 0.1 2.6 2 1 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KXH50111.1 - 4.7e-24 85.0 0.0 4.7e-24 85.0 0.0 3.3 4 0 0 4 4 4 1 Microtubule binding Microtub_bind PF13931.6 KXH50111.1 - 4.9e-07 30.2 1.5 4.9e-07 30.2 1.5 5.4 3 1 2 5 5 5 1 Kinesin-associated microtubule-binding Halogen_Hydrol PF10112.9 KXH50111.1 - 0.0082 16.2 2.3 0.0082 16.2 2.3 4.9 3 2 0 4 4 4 1 5-bromo-4-chloroindolyl phosphate hydrolysis protein P22_AR_C PF10548.9 KXH50111.1 - 0.091 12.9 0.3 0.82 9.9 0.1 2.6 2 0 0 2 2 2 0 P22AR C-terminal domain Apolipoprotein PF01442.18 KXH50111.1 - 0.35 10.7 68.9 0.046 13.6 17.4 4.6 1 1 3 4 4 4 0 Apolipoprotein A1/A4/E domain Gp-FAR-1 PF05823.12 KXH50111.1 - 3 8.2 20.0 6.3 7.2 0.1 5.1 3 1 1 5 5 5 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) GST_N_4 PF17172.4 KXH50113.1 - 8.8e-19 68.1 0.0 2.1e-18 66.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 KXH50113.1 - 6.1e-06 25.9 0.0 1.5e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 KXH50113.1 - 0.00022 21.6 0.0 0.00035 20.9 0.0 1.3 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_2 PF13410.6 KXH50113.1 - 0.072 13.1 0.0 0.17 11.9 0.0 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain UPF0183 PF03676.14 KXH50114.1 - 2.7e-54 185.0 0.0 1.6e-31 110.0 0.0 3.6 3 1 0 3 3 3 3 Uncharacterised protein family (UPF0183) Acetyltransf_10 PF13673.7 KXH50115.1 - 0.0017 18.3 0.1 0.0044 17.0 0.1 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXH50115.1 - 0.0052 17.2 0.1 0.012 16.1 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXH50115.1 - 0.0063 16.7 0.6 0.012 15.8 0.5 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Esterase_phd PF10503.9 KXH50116.1 - 8.1e-22 77.8 0.3 1.2e-21 77.3 0.3 1.2 1 0 0 1 1 1 1 Esterase PHB depolymerase CBM_1 PF00734.18 KXH50116.1 - 9e-12 44.7 16.8 4.8e-11 42.4 16.8 2.4 1 0 0 1 1 1 1 Fungal cellulose binding domain Peptidase_S9 PF00326.21 KXH50116.1 - 7.1e-10 38.7 1.0 1.1e-09 38.1 1.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.28 KXH50116.1 - 0.019 13.9 0.8 0.031 13.1 0.8 1.5 1 1 0 1 1 1 0 Carboxylesterase family Esterase PF00756.20 KXH50116.1 - 0.026 14.2 0.9 0.037 13.7 0.9 1.2 1 0 0 1 1 1 0 Putative esterase Abhydrolase_3 PF07859.13 KXH50116.1 - 0.064 13.1 0.0 0.097 12.5 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 KXH50116.1 - 0.076 12.8 0.1 0.14 11.9 0.1 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase MFS_1 PF07690.16 KXH50117.1 - 4e-20 72.0 24.0 4e-20 72.0 24.0 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily CENP-B_N PF04218.13 KXH50117.1 - 0.0016 18.0 0.0 0.0032 17.1 0.0 1.4 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain Trp_oprn_chp PF09534.10 KXH50117.1 - 0.2 11.5 4.9 2.9 7.6 0.4 3.2 1 1 2 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF2109 PF09882.9 KXH50117.1 - 8.7 6.4 12.9 2.3 8.3 0.6 4.3 5 0 0 5 5 5 0 Predicted membrane protein (DUF2109) Syja_N PF02383.18 KXH50118.1 - 1.3e-87 294.1 0.0 1.8e-87 293.7 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain ABC2_membrane_3 PF12698.7 KXH50118.1 - 0.83 8.7 5.1 1.4 8.0 5.1 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein Ras PF00071.22 KXH50119.1 - 1.9e-58 196.6 0.2 2.2e-58 196.4 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXH50119.1 - 3.7e-36 124.0 0.1 7.7e-36 122.9 0.1 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXH50119.1 - 9e-15 54.6 0.0 1.1e-14 54.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KXH50119.1 - 1.2e-06 28.1 0.0 1.5e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KXH50119.1 - 2.2e-06 27.4 0.0 3.2e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KXH50119.1 - 2.6e-06 27.5 0.0 3.9e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KXH50119.1 - 1.4e-05 25.1 0.8 0.084 12.8 0.1 2.4 1 1 2 3 3 3 2 RsgA GTPase AAA_16 PF13191.6 KXH50119.1 - 0.025 15.0 0.2 0.047 14.1 0.2 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 KXH50119.1 - 0.051 13.9 0.0 5.1 7.4 0.0 2.3 1 1 1 2 2 2 0 AAA domain TniB PF05621.11 KXH50119.1 - 0.084 12.3 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein GbpA_2 PF18416.1 KXH50119.1 - 0.15 12.3 1.1 5.6 7.3 0.0 2.3 1 1 1 2 2 2 0 N-acetylglucosamine binding protein domain 2 CARD_2 PF16739.5 KXH50217.1 - 0.048 13.6 0.2 0.67 10.0 0.3 2.5 2 0 0 2 2 2 0 Caspase recruitment domain SesA PF17107.5 KXH50217.1 - 0.075 13.2 0.8 0.69 10.1 0.0 2.3 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases tRNA_bind_2 PF13725.6 KXH50217.1 - 0.27 10.9 3.2 0.4 10.4 3.2 1.3 1 0 0 1 1 1 0 Possible tRNA binding domain SNCAIP_SNCA_bd PF16700.5 KXH50217.1 - 2.8 7.7 4.2 1.7 8.4 0.5 2.3 2 0 0 2 2 2 0 Synphilin-1 alpha-Synuclein-binding domain SesA PF17107.5 KXH50218.1 - 0.00037 20.7 0.6 0.0006 20.0 0.4 1.5 1 1 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases Helo_like_N PF17111.5 KXH50218.1 - 0.0013 18.2 0.4 0.0015 18.0 0.4 1.1 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins MetOD2 PF18548.1 KXH50218.1 - 0.058 13.5 0.1 4.7 7.4 0.0 2.4 2 0 0 2 2 2 0 Metanogen output domain 2 Pkinase PF00069.25 KXH50219.1 - 1e-22 80.8 0.0 1.4e-22 80.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXH50219.1 - 1.4e-09 37.7 0.0 4.2e-09 36.1 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXH50219.1 - 0.036 12.8 0.0 0.062 12.1 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase HATPase_c PF02518.26 KXH50220.1 - 3.8e-28 98.2 0.1 7e-28 97.4 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KXH50220.1 - 5.9e-22 78.0 0.3 1.4e-21 76.8 0.3 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 KXH50220.1 - 1.4e-21 76.2 0.6 4e-21 74.8 0.1 2.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.12 KXH50220.1 - 4.6e-17 62.1 0.2 1.6e-16 60.3 0.1 2.1 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 KXH50220.1 - 2.5e-11 43.8 0.0 0.00016 21.9 0.0 4.5 4 0 0 4 4 4 3 PAS domain PAS_4 PF08448.10 KXH50220.1 - 1.6e-10 41.2 0.1 0.00011 22.5 0.0 4.6 4 1 0 4 4 4 2 PAS fold PAS PF00989.25 KXH50220.1 - 7.1e-08 32.4 0.0 0.059 13.4 0.0 4.3 4 0 0 4 4 4 2 PAS fold PAS_8 PF13188.7 KXH50220.1 - 0.0002 21.3 0.1 0.12 12.4 0.0 4.1 4 0 0 4 4 4 1 PAS domain LPP PF04728.13 KXH50220.1 - 0.39 11.2 2.7 0.99 9.8 2.7 1.6 1 0 0 1 1 1 0 Lipoprotein leucine-zipper DPBB_1 PF03330.18 KXH50222.1 - 5.8e-08 32.9 0.0 1.5e-07 31.6 0.0 1.8 1 0 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 KXH50222.1 - 1e-05 25.3 0.2 1.9e-05 24.5 0.2 1.4 1 0 0 1 1 1 1 Barwin family HCO3_cotransp PF00955.21 KXH50223.1 - 0.021 13.7 0.9 0.031 13.1 0.9 1.1 1 0 0 1 1 1 0 HCO3- transporter family Abhydrolase_3 PF07859.13 KXH50224.1 - 8.4e-55 185.9 0.0 1e-54 185.6 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KXH50224.1 - 5.4e-07 28.8 0.1 2.4e-06 26.7 0.1 1.8 1 1 0 1 1 1 1 Carboxylesterase family Esterase_phd PF10503.9 KXH50224.1 - 0.0078 15.7 0.5 0.044 13.3 0.1 2.0 2 0 0 2 2 2 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 KXH50224.1 - 0.03 13.8 0.2 0.12 11.8 0.1 1.8 2 0 0 2 2 2 0 Prolyl oligopeptidase family DUF3112 PF11309.8 KXH50225.1 - 7.5e-08 32.1 13.8 2.4e-07 30.4 0.1 2.9 2 1 1 3 3 3 2 Protein of unknown function (DUF3112) DUF3671 PF12420.8 KXH50225.1 - 0.084 12.9 0.9 3.1 7.9 0.9 2.4 2 0 0 2 2 2 0 Protein of unknown function Oxidored_q3 PF00499.20 KXH50225.1 - 3.5 7.4 10.5 29 4.4 8.7 2.5 2 1 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 HsbA PF12296.8 KXH50226.1 - 6.1e-24 84.8 18.3 6.1e-24 84.8 18.3 1.4 2 0 0 2 2 2 1 Hydrophobic surface binding protein A NPR2 PF06218.11 KXH50226.1 - 0.18 10.5 0.0 0.21 10.3 0.0 1.2 1 0 0 1 1 1 0 Nitrogen permease regulator 2 DUF2076 PF09849.9 KXH50226.1 - 0.3 11.1 3.0 0.16 12.0 0.6 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) DUF390 PF04094.14 KXH50226.1 - 1.2 7.3 8.1 1.2 7.3 7.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF390) DUF2379 PF09543.10 KXH50226.1 - 1.2 9.3 4.2 0.64 10.2 0.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2379) AAA PF00004.29 KXH50228.1 - 1e-15 58.3 0.0 2e-15 57.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Zot PF05707.12 KXH50228.1 - 0.0057 16.3 0.0 0.019 14.6 0.0 1.8 2 1 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_16 PF13191.6 KXH50228.1 - 0.016 15.6 0.0 0.042 14.2 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain RuvB_N PF05496.12 KXH50228.1 - 0.019 14.7 0.1 0.15 11.8 0.0 2.2 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KXH50228.1 - 0.028 14.7 0.1 0.093 13.0 0.0 1.9 2 1 0 2 2 2 0 AAA domain AAA_5 PF07728.14 KXH50228.1 - 0.079 13.0 0.1 0.16 11.9 0.1 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) TsaE PF02367.17 KXH50228.1 - 0.43 10.6 1.7 0.68 9.9 0.2 2.1 2 1 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SpoIIIAH PF12685.7 KXH50228.1 - 0.49 10.2 6.5 1 9.1 6.5 1.4 1 0 0 1 1 1 0 SpoIIIAH-like protein DUF4381 PF14316.6 KXH50229.1 - 0.00094 19.4 0.5 0.0024 18.1 0.2 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4381) Herpes_gE PF02480.16 KXH50229.1 - 0.09 11.5 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Epimerase PF01370.21 KXH50230.1 - 8.3e-06 25.4 0.0 0.0081 15.7 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 KXH50230.1 - 0.0021 18.3 0.0 0.0044 17.3 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 KXH50230.1 - 0.016 15.7 0.1 0.047 14.1 0.0 1.9 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Peroxidase_2 PF01328.17 KXH50231.1 - 3e-53 181.1 0.0 3.5e-53 180.9 0.0 1.0 1 0 0 1 1 1 1 Peroxidase, family 2 Ank_2 PF12796.7 KXH50232.1 - 1.1e-33 115.6 2.4 3.5e-08 33.9 0.2 6.7 5 1 1 6 6 6 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXH50232.1 - 8.6e-23 78.0 2.3 0.44 11.3 0.0 11.3 11 0 0 11 11 11 6 Ankyrin repeat Ank_5 PF13857.6 KXH50232.1 - 4.3e-22 77.9 3.2 6e-06 26.4 0.0 8.4 5 2 3 8 8 8 6 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXH50232.1 - 5.7e-17 61.8 4.0 0.0076 16.8 0.0 8.1 4 1 5 9 9 9 5 Ankyrin repeats (many copies) Ank PF00023.30 KXH50232.1 - 1e-11 44.7 11.1 3 8.5 0.1 10.4 11 0 0 11 11 11 4 Ankyrin repeat Helo_like_N PF17111.5 KXH50232.1 - 1.1e-09 38.0 0.3 2.5e-09 36.8 0.3 1.6 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins NACHT PF05729.12 KXH50232.1 - 2.7e-07 30.6 0.0 7.6e-07 29.2 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KXH50232.1 - 0.00063 20.2 0.0 0.0025 18.2 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain KAP_NTPase PF07693.14 KXH50232.1 - 0.0065 15.7 0.8 0.016 14.4 0.7 1.7 1 1 0 1 1 1 1 KAP family P-loop domain Cutinase PF01083.22 KXH50233.1 - 2e-44 151.7 0.0 2.4e-44 151.4 0.0 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 KXH50233.1 - 0.00026 20.6 0.0 0.00037 20.1 0.0 1.2 1 0 0 1 1 1 1 PE-PPE domain VirJ PF06057.11 KXH50233.1 - 0.0037 17.2 0.0 0.0054 16.6 0.0 1.2 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) DUF2974 PF11187.8 KXH50233.1 - 0.0081 15.7 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_1 PF00561.20 KXH50233.1 - 0.032 13.9 0.0 0.04 13.6 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 KXH50233.1 - 0.17 11.7 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase GMC_oxred_N PF00732.19 KXH50234.1 - 5.2e-61 206.6 0.0 6.5e-61 206.3 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXH50234.1 - 6.5e-31 107.8 0.0 1.1e-30 107.1 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KXH50234.1 - 1.5e-06 27.5 0.2 0.0012 18.0 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KXH50234.1 - 0.00017 21.8 1.1 0.0004 20.6 1.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXH50234.1 - 0.0004 19.7 0.2 0.0071 15.6 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KXH50234.1 - 0.00075 18.6 0.3 0.0012 17.9 0.3 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.14 KXH50234.1 - 0.0015 17.3 1.3 0.027 13.2 0.3 2.2 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.6 KXH50234.1 - 0.0017 17.7 0.4 1.1 8.5 0.3 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXH50234.1 - 0.0064 16.1 3.9 0.019 14.6 1.3 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KXH50234.1 - 0.023 15.2 1.1 0.071 13.7 0.8 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KXH50234.1 - 0.039 13.2 0.2 0.066 12.4 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 KXH50234.1 - 0.045 13.0 0.4 0.12 11.5 0.1 1.8 2 0 0 2 2 2 0 Thi4 family GIDA PF01134.22 KXH50234.1 - 0.31 10.1 1.5 5.8 5.9 0.2 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Trp_halogenase PF04820.14 KXH50234.1 - 0.31 9.8 0.8 0.45 9.3 0.8 1.1 1 0 0 1 1 1 0 Tryptophan halogenase Fungal_trans PF04082.18 KXH50235.1 - 0.00026 20.1 0.0 0.0005 19.2 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyoxalase PF00903.25 KXH50236.1 - 5.5e-07 29.8 0.2 7.1e-06 26.2 0.2 2.0 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 KXH50236.1 - 0.008 16.1 0.0 0.016 15.2 0.0 1.4 1 0 0 1 1 1 1 Glyoxalase-like domain HsbA PF12296.8 KXH50237.1 - 4.8e-22 78.6 3.7 1.4e-20 73.9 1.5 2.3 2 0 0 2 2 2 2 Hydrophobic surface binding protein A Caps_synth PF05704.12 KXH50239.1 - 0.0034 16.8 0.5 0.013 14.9 0.5 1.7 1 1 0 1 1 1 1 Capsular polysaccharide synthesis protein Gly_transf_sug PF04488.15 KXH50239.1 - 0.099 13.3 0.0 0.16 12.6 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase sugar-binding region containing DXD motif LVIVD PF08309.11 KXH50240.1 - 0.027 13.8 0.9 0.43 9.9 0.5 2.7 2 0 0 2 2 2 0 LVIVD repeat Helo_like_N PF17111.5 KXH50241.1 - 6.6e-05 22.4 1.4 0.0032 16.9 0.1 2.6 2 1 0 2 2 2 2 Fungal N-terminal domain of STAND proteins Baculo_PEP_C PF04513.12 KXH50241.1 - 0.021 14.9 7.0 2.6 8.1 0.1 3.2 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus CCDC-167 PF15188.6 KXH50241.1 - 0.025 14.9 0.2 0.025 14.9 0.2 3.8 4 1 0 4 4 4 0 Coiled-coil domain-containing protein 167 SKA2 PF16740.5 KXH50241.1 - 0.034 13.9 3.4 3.1 7.6 0.0 3.3 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 2 DUF720 PF05302.11 KXH50241.1 - 0.077 12.9 1.2 0.15 11.9 0.0 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF720) GIT_CC PF16559.5 KXH50241.1 - 0.37 10.7 4.7 0.28 11.1 0.5 2.6 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor Aminotran_1_2 PF00155.21 KXH50242.1 - 4.1e-90 302.6 0.0 4.7e-90 302.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Tropomyosin_1 PF12718.7 KXH50243.1 - 0.26 11.4 4.2 1 9.5 0.8 2.3 1 1 0 2 2 2 0 Tropomyosin like ECH_1 PF00378.20 KXH50244.1 - 5.7e-54 183.1 0.0 6.5e-39 133.7 0.0 2.0 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXH50244.1 - 1.1e-23 84.3 0.1 2e-10 40.7 0.0 2.9 2 1 1 3 3 3 3 Enoyl-CoA hydratase/isomerase Sugar_tr PF00083.24 KXH50245.1 - 5.4e-109 365.0 20.7 6.1e-109 364.9 20.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH50245.1 - 5.4e-29 101.2 54.6 6e-24 84.6 23.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KXH50245.1 - 0.0015 16.9 0.5 0.0036 15.7 0.5 1.6 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family Fungal_trans_2 PF11951.8 KXH50246.1 - 1.2e-16 60.5 2.9 2.6e-16 59.4 2.9 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH50246.1 - 5.2e-07 29.7 12.1 9.7e-07 28.8 12.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Transketolase_N PF00456.21 KXH50247.1 - 8.4e-132 439.2 0.1 1.5e-131 438.3 0.1 1.3 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 KXH50247.1 - 7.1e-37 126.8 0.0 2.4e-36 125.1 0.0 1.8 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KXH50247.1 - 3.6e-09 36.6 0.0 9e-09 35.3 0.0 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 KXH50247.1 - 3.6e-07 29.7 0.0 1.1e-06 28.1 0.0 1.7 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.20 KXH50247.1 - 4.3e-07 29.2 0.1 8.2e-07 28.3 0.1 1.4 1 0 0 1 1 1 1 Dehydrogenase E1 component adh_short_C2 PF13561.6 KXH50248.1 - 1.9e-49 168.4 0.0 2.6e-49 167.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXH50248.1 - 6.6e-38 130.1 0.1 7.9e-38 129.9 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXH50248.1 - 1.5e-08 34.8 0.1 2.1e-08 34.3 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXH50248.1 - 0.0017 17.9 0.0 1.5 8.2 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Transp_cyt_pur PF02133.15 KXH50250.1 - 2.1e-154 514.5 33.5 2.4e-154 514.4 33.5 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Glyco_trans_2_3 PF13632.6 KXH50251.1 - 2.5e-06 27.5 10.0 0.0024 17.8 9.1 3.4 1 1 1 2 2 2 2 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 KXH50251.1 - 5.4e-05 22.7 0.0 0.0022 17.5 0.0 2.8 2 1 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 KXH50251.1 - 6.1e-05 22.9 0.0 0.00019 21.3 0.0 1.7 1 1 1 2 2 2 1 Glycosyl transferase family 2 PhoD_N PF16655.5 KXH50252.1 - 1.3e-31 109.0 0.2 2.4e-31 108.1 0.2 1.5 1 0 0 1 1 1 1 PhoD-like phosphatase, N-terminal domain PhoD PF09423.10 KXH50252.1 - 8.4e-26 90.8 0.2 1.1e-25 90.5 0.2 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase Pur_ac_phosph_N PF16656.5 KXH50252.1 - 0.00041 20.8 0.7 0.001 19.6 0.7 1.7 1 1 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Gcw_chp PF09694.10 KXH50252.1 - 0.033 14.2 0.1 0.051 13.5 0.1 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (Gcw_chp) PhoD PF09423.10 KXH50253.1 - 1.2e-70 238.3 2.3 1.4e-70 238.1 2.3 1.0 1 0 0 1 1 1 1 PhoD-like phosphatase DUF5012 PF16404.5 KXH50253.1 - 0.11 12.6 1.4 0.32 11.1 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5012) Herpes_DNAp_acc PF04929.12 KXH50256.1 - 3.2 6.6 7.1 4.3 6.2 7.1 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor TPR_12 PF13424.6 KXH50257.1 - 1.1e-13 51.2 19.1 0.005 17.1 2.1 8.2 7 1 2 9 9 9 5 Tetratricopeptide repeat TPR_7 PF13176.6 KXH50257.1 - 4e-08 32.7 7.7 1.4 9.1 0.0 7.1 6 0 0 6 6 6 2 Tetratricopeptide repeat AAA_22 PF13401.6 KXH50257.1 - 3.4e-06 27.4 0.0 1.6e-05 25.2 0.0 2.2 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 KXH50257.1 - 1.5e-05 24.9 0.0 7e-05 22.8 0.0 2.2 1 0 0 1 1 1 1 NACHT domain TPR_1 PF00515.28 KXH50257.1 - 0.0015 18.3 4.9 13 5.8 0.1 6.0 6 0 0 6 6 6 1 Tetratricopeptide repeat AAA_16 PF13191.6 KXH50257.1 - 0.0027 18.1 0.0 0.011 16.1 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain TPR_14 PF13428.6 KXH50257.1 - 0.013 16.3 1.2 2.3e+02 3.1 0.0 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_19 PF14559.6 KXH50257.1 - 0.03 14.8 1.8 18 5.9 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 KXH50257.1 - 0.041 14.5 3.1 16 6.4 0.2 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat Vps39_1 PF10366.9 KXH50257.1 - 0.34 11.2 2.9 0.99 9.7 0.7 3.0 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 FMO-like PF00743.19 KXH50258.1 - 6.1e-18 64.5 0.0 3.1e-17 62.2 0.0 2.0 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KXH50258.1 - 2.2e-16 60.0 0.2 2e-15 56.9 0.4 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXH50258.1 - 1.9e-13 50.4 0.0 2.2e-12 46.8 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXH50258.1 - 1.5e-10 40.8 0.0 7.5e-09 35.2 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KXH50258.1 - 1.3e-05 25.3 0.3 5.9e-05 23.2 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXH50258.1 - 0.00027 20.6 6.3 0.0035 17.0 4.0 2.8 2 1 1 3 3 3 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 KXH50258.1 - 0.00032 20.0 0.7 0.056 12.7 0.3 2.2 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 KXH50258.1 - 0.00036 21.0 3.4 0.084 13.4 0.0 2.6 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 KXH50258.1 - 0.0042 17.1 0.1 2.5 8.2 0.0 2.5 3 0 0 3 3 3 2 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.6 KXH50258.1 - 0.0084 16.1 1.7 0.45 10.5 0.1 3.4 4 0 0 4 4 4 1 FAD-NAD(P)-binding 3HCDH_N PF02737.18 KXH50258.1 - 0.0095 15.8 0.5 0.015 15.2 0.5 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.14 KXH50258.1 - 0.028 13.2 1.0 0.4 9.3 0.6 2.6 3 0 0 3 3 3 0 HI0933-like protein FAD_oxidored PF12831.7 KXH50258.1 - 0.25 10.6 0.2 0.47 9.7 0.0 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.22 KXH50258.1 - 1.6 7.8 3.5 1 8.4 0.8 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_2 PF00890.24 KXH50258.1 - 3.5 6.6 9.2 0.059 12.4 2.3 1.5 2 0 0 2 2 2 0 FAD binding domain Sas10_Utp3 PF04000.15 KXH50259.1 - 6.3e-17 62.0 0.7 6.3e-17 62.0 0.7 1.8 2 0 0 2 2 2 1 Sas10/Utp3/C1D family CDV3 PF15359.6 KXH50259.1 - 1.3 9.6 6.1 0.29 11.6 1.6 2.2 2 0 0 2 2 2 0 Carnitine deficiency-associated protein 3 EMP70 PF02990.16 KXH50260.1 - 6.5e-201 668.5 5.0 9.3e-201 668.0 5.0 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 Med4 PF10018.9 KXH50261.1 - 6.8e-41 140.1 1.4 1.5e-40 139.0 1.4 1.6 1 1 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 KIAA1430 PF13879.6 KXH50261.1 - 0.0022 18.7 0.5 0.0022 18.7 0.5 2.1 2 0 0 2 2 2 1 KIAA1430 homologue DUF4065 PF13274.6 KXH50261.1 - 0.082 13.8 0.2 3.5 8.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4065) DUF4407 PF14362.6 KXH50261.1 - 1.6 8.0 8.4 6.3 6.1 3.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Pyr_redox_2 PF07992.14 KXH50270.1 - 4.4e-22 78.7 0.5 6.2e-22 78.2 0.5 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXH50270.1 - 4.1e-05 23.7 0.0 0.00023 21.3 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KXH50270.1 - 4.7e-05 22.3 0.0 0.0036 16.1 0.0 2.2 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.19 KXH50270.1 - 0.00023 20.5 0.0 0.00043 19.6 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KXH50270.1 - 0.00027 20.6 0.7 0.0009 18.9 0.4 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KXH50270.1 - 0.00033 19.9 0.1 0.003 16.7 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.6 KXH50270.1 - 0.00059 19.2 1.6 0.03 13.6 0.3 2.9 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXH50270.1 - 0.0025 17.0 0.0 1.1 8.4 0.0 2.1 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.22 KXH50270.1 - 0.0035 16.5 0.0 0.0058 15.8 0.0 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.17 KXH50270.1 - 0.0052 16.1 0.0 0.01 15.1 0.0 1.5 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 KXH50270.1 - 0.0076 16.2 0.2 0.36 10.8 0.0 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KXH50270.1 - 0.021 13.9 0.0 0.051 12.6 0.0 1.7 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_oxidored PF12831.7 KXH50270.1 - 0.037 13.4 0.0 0.058 12.7 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Cytochrom_C PF00034.21 KXH50270.1 - 0.067 14.3 0.0 0.16 13.1 0.0 1.7 1 0 0 1 1 1 0 Cytochrome c Mito_carr PF00153.27 KXH50271.1 - 4.2e-48 161.2 2.4 1.8e-19 69.5 0.2 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein Phage_holin_3_1 PF05106.12 KXH50271.1 - 0.083 13.3 3.2 15 6.1 0.1 3.6 3 1 0 4 4 4 0 Phage holin family (Lysis protein S) HET PF06985.11 KXH50273.1 - 1.4e-26 93.6 0.0 3.2e-26 92.4 0.0 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Rad54_N PF08658.10 KXH50274.1 - 1.2e-58 198.2 3.1 7e-58 195.8 3.6 1.9 2 0 0 2 2 2 1 Rad54 N terminal SNF2_N PF00176.23 KXH50274.1 - 5.3e-58 196.4 0.0 1e-57 195.5 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KXH50274.1 - 7.6e-16 58.4 0.0 1.8e-15 57.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXH50274.1 - 2.6e-08 34.0 0.0 7.1e-08 32.6 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 KXH50274.1 - 0.0016 17.7 0.0 0.0065 15.7 0.0 1.9 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Citrate_ly_lig PF08218.11 KXH50274.1 - 0.068 12.9 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Citrate lyase ligase C-terminal domain SWI2_SNF2 PF18766.1 KXH50274.1 - 0.11 12.2 0.1 0.34 10.5 0.0 1.9 2 1 0 2 2 2 0 SWI2/SNF2 ATPase Glyco_transf_24 PF18404.1 KXH50275.1 - 3.7e-148 492.2 3.4 5.6e-148 491.6 3.4 1.3 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 KXH50275.1 - 1.2e-69 235.1 0.1 4e-69 233.4 0.1 1.9 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_15 PF18403.1 KXH50275.1 - 9.4e-55 185.8 0.5 1.1e-53 182.4 0.0 2.5 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_13 PF18401.1 KXH50275.1 - 6e-48 162.2 1.1 4.2e-46 156.3 0.3 3.0 4 0 0 4 4 4 1 Thioredoxin-like domain Thioredoxin_12 PF18400.1 KXH50275.1 - 4.6e-47 160.3 0.0 1.1e-46 159.2 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 KXH50275.1 - 1.2e-42 144.5 0.0 2.5e-42 143.4 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.20 KXH50275.1 - 2.7e-06 27.2 0.3 5.1e-06 26.2 0.3 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 8 Coatomer_WDAD PF04053.14 KXH50276.1 - 9.4e-146 486.4 0.0 2e-145 485.2 0.0 1.6 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.11 KXH50276.1 - 1e-99 334.1 0.0 1.4e-99 333.6 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.32 KXH50276.1 - 7.1e-35 118.4 16.6 2.5e-07 31.3 0.2 7.7 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXH50276.1 - 1.1e-08 35.3 0.6 0.0016 18.7 0.0 5.5 3 2 4 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain Clathrin PF00637.20 KXH50276.1 - 0.02 14.7 0.4 0.19 11.6 0.0 2.3 2 0 0 2 2 2 0 Region in Clathrin and VPS Nup160 PF11715.8 KXH50276.1 - 0.022 13.4 7.1 2.4 6.7 0.1 3.9 2 1 1 4 4 4 0 Nucleoporin Nup120/160 IPPT PF01715.17 KXH50276.1 - 0.074 12.9 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 IPP transferase CSN8_PSD8_EIF3K PF10075.9 KXH50277.1 - 7.9e-20 71.3 0.0 1.1e-19 70.8 0.0 1.2 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family Dehydratase_hem PF13816.6 KXH50277.1 - 0.16 11.4 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 Haem-containing dehydratase SAC3_GANP PF03399.16 KXH50277.1 - 0.18 11.1 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 SAC3/GANP family GSP_synth PF03738.14 KXH50278.1 - 9.6e-115 383.7 0.0 1.1e-114 383.5 0.0 1.1 1 0 0 1 1 1 1 Glutathionylspermidine synthase preATP-grasp ScsC_N PF18312.1 KXH50278.1 - 0.091 12.6 0.1 0.37 10.6 0.0 2.0 2 0 0 2 2 2 0 Copper resistance protein ScsC N-terminal domain DUF4124 PF13511.6 KXH50279.1 - 0.011 16.0 1.2 0.02 15.2 1.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4124) TFCD_C PF12612.8 KXH50282.1 - 1.8e-23 83.3 0.3 7e-23 81.4 0.1 2.2 2 0 0 2 2 2 1 Tubulin folding cofactor D C terminal HEAT PF02985.22 KXH50282.1 - 0.0043 17.2 2.1 1.5 9.2 0.0 4.9 5 0 0 5 5 5 1 HEAT repeat IFRD PF05004.13 KXH50282.1 - 0.012 14.8 1.3 0.38 9.8 0.5 2.7 2 0 0 2 2 2 0 Interferon-related developmental regulator (IFRD) HEAT_2 PF13646.6 KXH50282.1 - 0.026 14.9 7.0 1.4 9.4 0.1 4.7 5 0 0 5 5 5 0 HEAT repeats Pyr_redox_2 PF07992.14 KXH50285.1 - 1e-52 179.2 0.2 1.4e-52 178.8 0.2 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXH50285.1 - 1.4e-12 48.0 0.0 6.4e-11 42.7 0.1 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXH50285.1 - 0.0081 15.4 0.6 3.4 6.8 0.0 2.4 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase EcoR124_C PF12008.8 KXH50285.1 - 0.021 14.5 0.4 0.045 13.4 0.0 1.6 2 0 0 2 2 2 0 Type I restriction and modification enzyme - subunit R C terminal NAD_binding_7 PF13241.6 KXH50285.1 - 0.082 13.4 0.0 11 6.5 0.0 2.6 2 0 0 2 2 2 0 Putative NAD(P)-binding MFS_1 PF07690.16 KXH50286.1 - 9.6e-22 77.4 56.1 5e-16 58.6 34.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily KNOX1 PF03790.13 KXH50286.1 - 0.18 11.5 0.2 0.36 10.6 0.2 1.4 1 0 0 1 1 1 0 KNOX1 domain A_deaminase PF00962.22 KXH50287.1 - 7.4e-34 117.5 0.0 9.3e-34 117.2 0.0 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase TatD_DNase PF01026.21 KXH50287.1 - 0.0061 16.0 0.0 0.0072 15.7 0.0 1.2 1 0 0 1 1 1 1 TatD related DNase WD40 PF00400.32 KXH50288.1 - 1.3e-37 127.1 19.6 3.1e-07 31.0 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXH50288.1 - 2.4e-14 53.4 0.0 0.00038 20.7 0.1 4.7 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KXH50288.1 - 7.3e-05 21.9 0.1 0.8 8.6 0.0 3.9 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KXH50288.1 - 8.9e-05 22.4 0.0 0.11 12.3 0.0 2.8 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KXH50288.1 - 0.00071 19.0 0.0 0.05 12.9 0.0 2.9 2 1 1 3 3 3 1 WD40-like domain Phosducin PF02114.16 KXH50290.1 - 5.1e-09 35.5 0.1 7.2e-08 31.7 0.1 2.2 1 1 0 1 1 1 1 Phosducin Ran_BP1 PF00638.18 KXH50292.1 - 1.5e-49 167.3 1.4 2.6e-49 166.6 1.4 1.4 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.23 KXH50292.1 - 0.0015 18.5 0.2 0.0052 16.7 0.2 1.8 1 1 0 1 1 1 1 WH1 domain CDC27 PF09507.10 KXH50292.1 - 0.11 11.9 14.4 0.16 11.4 14.4 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 VID27_PH PF17747.1 KXH50292.1 - 0.12 12.7 0.1 0.17 12.2 0.1 1.3 1 1 0 1 1 1 0 VID27 PH-like domain PHD20L1_u1 PF16660.5 KXH50292.1 - 0.32 11.8 2.7 0.67 10.7 2.7 1.5 1 0 0 1 1 1 0 PHD finger protein 20-like protein 1 YEATS PF03366.16 KXH50293.1 - 2e-21 75.7 0.0 4.8e-21 74.5 0.0 1.7 1 0 0 1 1 1 1 YEATS family BET PF17035.5 KXH50293.1 - 1.4e-05 25.2 0.9 0.0049 17.0 0.2 3.0 3 0 0 3 3 3 2 Bromodomain extra-terminal - transcription regulation p25-alpha PF05517.12 KXH50293.1 - 0.0067 16.6 0.2 0.043 14.0 0.2 1.9 1 1 1 2 2 2 1 p25-alpha MgtE_N PF03448.17 KXH50293.1 - 0.038 14.6 0.1 0.074 13.7 0.1 1.4 1 0 0 1 1 1 0 MgtE intracellular N domain WWE PF02825.20 KXH50293.1 - 0.056 14.0 0.1 0.22 12.1 0.1 1.9 2 0 0 2 2 2 0 WWE domain DUF3791 PF12668.7 KXH50293.1 - 0.13 12.3 0.0 0.44 10.6 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3791) Zn_clus PF00172.18 KXH50294.1 - 2.9e-07 30.5 12.1 4.7e-07 29.8 12.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LCE6A PF15858.5 KXH50294.1 - 7.2 7.4 10.5 0.28 12.0 3.8 2.2 2 0 0 2 2 2 0 Late cornified envelope protein 6A family PP2C PF00481.21 KXH50295.1 - 6.7e-64 216.0 0.2 1.7e-52 178.6 0.2 3.0 1 1 1 2 2 2 2 Protein phosphatase 2C Snf7 PF03357.21 KXH50296.1 - 1.5e-26 93.0 25.3 3.1e-26 92.0 24.1 2.0 2 1 0 2 2 2 1 Snf7 CaMBD PF02888.16 KXH50296.1 - 0.025 14.8 1.2 0.025 14.8 1.2 1.9 2 0 0 2 2 2 0 Calmodulin binding domain DUF4347 PF14252.6 KXH50296.1 - 0.058 13.2 0.6 0.18 11.7 0.5 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4347) CCAP PF11105.8 KXH50296.1 - 0.08 12.9 0.5 0.08 12.9 0.5 1.9 2 0 0 2 2 2 0 Arthropod cardioacceleratory peptide 2a 7TMR-HDED PF07697.11 KXH50296.1 - 0.09 12.9 3.9 0.13 12.3 3.9 1.2 1 0 0 1 1 1 0 7TM-HD extracellular Exonuc_VII_L PF02601.15 KXH50296.1 - 0.095 12.3 4.5 0.13 11.8 4.5 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit GCN5L1 PF06320.13 KXH50296.1 - 0.33 11.1 6.6 0.15 12.2 1.6 2.1 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) Spc24 PF08286.11 KXH50296.1 - 1.7 8.9 6.8 3.2 8.0 6.8 1.7 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 PspA_IM30 PF04012.12 KXH50296.1 - 1.7 8.2 18.1 3 7.3 5.6 2.1 1 1 1 2 2 2 0 PspA/IM30 family YojJ PF10372.9 KXH50296.1 - 5.9 7.1 10.4 2.1 8.5 2.0 3.3 1 1 2 3 3 3 0 Bacterial membrane-spanning protein N-terminus CENP-H PF05837.12 KXH50296.1 - 8.2 6.9 11.3 3.4 8.1 7.8 1.9 1 1 0 2 2 2 0 Centromere protein H (CENP-H) Dynamin_N PF00350.23 KXH50297.1 - 1.5e-17 64.1 0.1 4.3e-17 62.7 0.0 1.8 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 KXH50297.1 - 4.1e-10 39.8 0.0 2.4e-09 37.3 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KXH50297.1 - 1.6e-06 27.8 1.3 4.3e-05 23.1 0.9 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MSA-2c PF12238.8 KXH50297.1 - 0.014 15.4 2.0 0.041 13.9 1.1 2.3 3 0 0 3 3 3 0 Merozoite surface antigen 2c cobW PF02492.19 KXH50297.1 - 0.023 14.3 0.7 0.58 9.7 0.7 2.7 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain TsaE PF02367.17 KXH50297.1 - 0.043 13.8 0.0 0.14 12.2 0.0 1.8 1 1 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Roc PF08477.13 KXH50297.1 - 0.06 13.6 0.1 0.9 9.8 0.0 2.4 1 1 1 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_18 PF13238.6 KXH50297.1 - 0.062 13.8 0.0 0.21 12.1 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KXH50297.1 - 0.067 13.0 0.1 0.3 10.8 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain IIGP PF05049.13 KXH50297.1 - 0.082 12.0 0.0 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) DUF2408 PF10303.9 KXH50297.1 - 0.34 11.5 1.9 5.4 7.6 0.1 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) Cofilin_ADF PF00241.20 KXH50298.1 - 0.017 14.9 0.6 0.051 13.4 0.0 2.1 3 0 0 3 3 3 0 Cofilin/tropomyosin-type actin-binding protein Rft-1 PF04506.13 KXH50299.1 - 0.22 10.2 0.2 0.27 9.9 0.2 1.1 1 0 0 1 1 1 0 Rft protein Trypsin_2 PF13365.6 KXH50300.1 - 1.5e-29 103.8 0.0 2.9e-29 102.9 0.0 1.4 1 1 0 1 1 1 1 Trypsin-like peptidase domain Peptidase_S46 PF10459.9 KXH50300.1 - 0.0072 15.0 0.0 0.075 11.7 0.1 2.0 2 0 0 2 2 2 1 Peptidase S46 Peptidase_S32 PF05579.13 KXH50300.1 - 0.014 14.6 0.2 0.026 13.7 0.2 1.4 1 0 0 1 1 1 0 Equine arteritis virus serine endopeptidase S32 DUF4388 PF14332.6 KXH50300.1 - 0.18 12.1 0.0 0.26 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4388) K_oxygenase PF13434.6 KXH50301.1 - 3.3e-12 46.2 0.0 9.8e-12 44.7 0.0 1.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.19 KXH50301.1 - 4.4e-08 32.0 0.0 6.4e-08 31.5 0.0 1.1 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KXH50301.1 - 4.2e-06 26.2 0.0 1e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXH50301.1 - 8.7e-06 25.2 0.0 2.9e-05 23.4 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Fig1 PF12351.8 KXH50302.1 - 0.069 13.1 2.3 1.6 8.6 0.7 2.3 1 1 1 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 LSM PF01423.22 KXH50432.1 - 1.8e-16 59.5 0.2 2.7e-16 59.0 0.2 1.3 1 0 0 1 1 1 1 LSM domain DPPIV_N PF00930.21 KXH50433.1 - 2.7e-107 358.6 0.4 3.9e-107 358.1 0.4 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 KXH50433.1 - 3.1e-38 131.4 0.1 5.5e-38 130.6 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 KXH50433.1 - 0.00075 20.2 0.1 0.0021 18.7 0.1 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXH50433.1 - 0.011 15.0 0.1 0.051 12.8 0.0 2.0 2 1 0 2 2 2 0 Serine aminopeptidase, S33 Pkinase PF00069.25 KXH50435.1 - 7.7e-14 51.7 0.0 9.1e-11 41.6 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXH50435.1 - 8e-09 35.2 0.3 0.00036 19.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Choline_kinase PF01633.20 KXH50435.1 - 0.00016 21.4 0.0 0.00028 20.5 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 KXH50435.1 - 0.0042 17.0 0.4 0.016 15.2 0.3 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family P5CR_dimer PF14748.6 KXH50436.1 - 9.9e-36 122.1 0.1 9.9e-36 122.1 0.1 2.5 3 0 0 3 3 3 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 KXH50436.1 - 4.4e-18 65.6 3.0 1.2e-17 64.3 3.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 KXH50436.1 - 0.0076 16.4 0.8 0.015 15.5 0.8 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase CoA_binding PF02629.19 KXH50436.1 - 0.014 16.1 2.7 0.034 14.8 2.1 2.0 2 0 0 2 2 2 0 CoA binding domain Shikimate_DH PF01488.20 KXH50436.1 - 0.075 13.1 0.5 0.16 12.0 0.2 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase ABC_cobalt PF09819.9 KXH50436.1 - 0.078 13.1 0.2 0.2 11.8 0.2 1.7 1 0 0 1 1 1 0 ABC-type cobalt transport system, permease component NAD_Gly3P_dh_N PF01210.23 KXH50436.1 - 0.37 10.8 5.3 1.6 8.7 3.9 2.4 2 1 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus PhyH PF05721.13 KXH50438.1 - 3.2e-21 76.6 0.0 4.2e-21 76.2 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) FAD_binding_3 PF01494.19 KXH50439.1 - 1.1e-08 34.8 1.2 0.02 14.2 0.1 3.2 3 0 0 3 3 3 3 FAD binding domain DAO PF01266.24 KXH50439.1 - 0.02 14.5 0.2 0.033 13.8 0.2 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXH50439.1 - 0.028 14.6 0.2 0.059 13.6 0.2 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXH50439.1 - 0.056 12.7 0.0 0.088 12.0 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXH50439.1 - 0.11 12.5 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding TTSSLRR PF12468.8 KXH50440.1 - 0.056 13.7 1.1 3.1 8.1 0.2 2.4 2 0 0 2 2 2 0 Type III secretion system leucine rich repeat protein Ring_hydroxyl_A PF00848.19 KXH50441.1 - 5.9e-24 85.2 4.6 4.8e-11 43.0 2.0 2.3 1 1 1 2 2 2 2 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.26 KXH50441.1 - 1.5e-13 50.4 0.0 3e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain DIOX_N PF14226.6 KXH50442.1 - 1.2e-31 109.9 0.1 2.4e-31 108.9 0.1 1.5 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KXH50442.1 - 1e-22 80.5 0.0 7.1e-22 77.8 0.0 2.1 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Acyl_transf_3 PF01757.22 KXH50443.1 - 7.7e-18 64.6 32.9 1.1e-17 64.1 32.9 1.3 1 0 0 1 1 1 1 Acyltransferase family ADH_zinc_N PF00107.26 KXH50444.1 - 7.1e-23 81.0 0.6 1.6e-22 79.9 0.6 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXH50444.1 - 7e-16 59.5 0.0 2.9e-15 57.5 0.1 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase p450 PF00067.22 KXH50444.1 - 5.4e-13 48.5 0.0 7.6e-13 48.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ADH_N PF08240.12 KXH50444.1 - 9.4e-07 28.7 0.3 2.1e-06 27.6 0.1 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 KXH50444.1 - 0.013 14.8 0.9 0.027 13.8 0.9 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain PHBC_N PF12551.8 KXH50444.1 - 3.4 7.5 6.3 2.4 8.0 0.2 3.5 4 0 0 4 4 4 0 Poly-beta-hydroxybutyrate polymerase N terminal Polysacc_deac_1 PF01522.21 KXH50445.1 - 5.9e-17 61.7 0.0 1.2e-16 60.7 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 KXH50445.1 - 1.9e-05 24.4 0.1 8.9e-05 22.2 0.0 2.1 2 1 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2334) Amidase PF01425.21 KXH50446.1 - 1.3e-109 367.1 0.0 1.8e-109 366.7 0.0 1.2 1 0 0 1 1 1 1 Amidase FAD_binding_3 PF01494.19 KXH50447.1 - 1.6e-69 234.8 0.0 2.1e-69 234.4 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 KXH50447.1 - 5e-27 95.0 0.0 9.7e-27 94.0 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain HI0933_like PF03486.14 KXH50447.1 - 8.8e-05 21.4 0.0 0.0007 18.4 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.14 KXH50447.1 - 0.00023 20.5 0.0 0.0063 15.8 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXH50447.1 - 0.00033 21.1 0.0 0.0053 17.3 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXH50447.1 - 0.00098 19.3 0.0 0.0025 18.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KXH50447.1 - 0.01 15.1 0.0 0.02 14.2 0.0 1.4 1 0 0 1 1 1 0 Thi4 family AlaDh_PNT_C PF01262.21 KXH50447.1 - 0.025 13.9 0.0 0.045 13.1 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 KXH50447.1 - 0.035 13.7 0.0 0.058 13.0 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Lycopene_cycl PF05834.12 KXH50447.1 - 0.043 12.9 0.1 0.067 12.2 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_2 PF00890.24 KXH50447.1 - 0.054 12.6 0.1 0.092 11.8 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain XdhC_C PF13478.6 KXH50447.1 - 0.072 13.6 0.0 0.15 12.6 0.0 1.5 1 0 0 1 1 1 0 XdhC Rossmann domain 2-Hacid_dh_C PF02826.19 KXH50447.1 - 0.11 11.8 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_oxidored PF12831.7 KXH50447.1 - 0.12 11.8 0.0 0.23 10.8 0.0 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase 3HCDH_N PF02737.18 KXH50447.1 - 0.13 12.1 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MFS_1 PF07690.16 KXH50448.1 - 9.4e-24 84.0 37.8 9.8e-18 64.2 13.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily OapA_N PF08525.11 KXH50448.1 - 0.033 14.1 1.1 7 6.7 0.6 2.8 2 0 0 2 2 2 0 Opacity-associated protein A N-terminal motif Oxidored_FMN PF00724.20 KXH50449.1 - 4.1e-77 259.8 0.0 5.7e-77 259.3 0.0 1.2 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family PAN_4 PF14295.6 KXH50450.1 - 0.19 11.7 6.6 4.1 7.4 0.2 3.0 2 1 0 2 2 2 0 PAN domain FAD_binding_3 PF01494.19 KXH50451.1 - 4.5e-20 72.2 0.0 2.1e-13 50.2 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 KXH50451.1 - 4e-06 26.1 0.0 6.6e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Trp_halogenase PF04820.14 KXH50451.1 - 4.3e-06 25.9 1.0 0.016 14.0 0.4 2.1 1 1 1 2 2 2 2 Tryptophan halogenase Pyr_redox_2 PF07992.14 KXH50451.1 - 4.3e-06 26.2 0.0 0.0034 16.6 0.1 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXH50451.1 - 3.6e-05 22.6 1.0 0.018 13.7 2.4 2.1 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_8 PF13450.6 KXH50451.1 - 0.00081 19.6 1.8 0.00081 19.6 1.8 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXH50451.1 - 0.00082 19.1 9.2 0.42 10.1 7.3 2.5 2 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KXH50451.1 - 0.003 16.7 5.7 0.0053 15.9 5.7 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 KXH50451.1 - 0.043 13.1 0.2 0.065 12.5 0.2 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXH50451.1 - 0.047 14.2 1.5 0.33 11.5 1.6 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KXH50451.1 - 0.077 12.3 0.8 9.5 5.4 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Methyltransf_16 PF10294.9 KXH50451.1 - 0.19 11.4 0.3 0.34 10.6 0.0 1.5 2 0 0 2 2 2 0 Lysine methyltransferase FAD_oxidored PF12831.7 KXH50451.1 - 0.37 10.1 6.0 0.56 9.5 6.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase 3HCDH_N PF02737.18 KXH50451.1 - 0.45 10.4 1.9 0.76 9.6 1.9 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.22 KXH50451.1 - 2.3 7.2 5.7 3.3 6.7 5.7 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A Fungal_trans PF04082.18 KXH50452.1 - 2.9e-42 144.5 0.5 4.3e-42 144.0 0.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KXH50452.1 - 1.7e-06 28.2 12.6 0.0013 19.1 1.8 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXH50452.1 - 7.3e-05 23.3 10.2 0.019 15.8 1.2 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 KXH50452.1 - 0.002 18.4 0.6 0.33 11.4 0.1 2.8 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KXH50452.1 - 0.045 14.1 1.5 0.33 11.3 0.0 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Glyco_hydro_18 PF00704.28 KXH50454.1 - 6.5e-14 52.4 0.0 1e-13 51.7 0.0 1.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_115 PF15979.5 KXH50455.1 - 9.2e-129 429.7 0.9 9.2e-129 429.7 0.9 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 115 GH115_C PF17829.1 KXH50455.1 - 6.6e-38 130.2 0.0 2.1e-37 128.6 0.0 1.9 2 0 0 2 2 2 1 Gylcosyl hydrolase family 115 C-terminal domain DUF2235 PF09994.9 KXH50456.1 - 1.9e-78 263.8 0.0 2.5e-78 263.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Myosin_TH1 PF06017.13 KXH50457.1 - 0.066 12.9 0.0 0.15 11.7 0.0 1.6 2 0 0 2 2 2 0 Unconventional myosin tail, actin- and lipid-binding PcfK PF14058.6 KXH50457.1 - 0.15 12.4 3.0 0.24 11.7 0.1 2.2 2 0 0 2 2 2 0 PcfK-like protein BRCT PF00533.26 KXH50459.1 - 0.0008 19.7 0.0 0.0087 16.4 0.0 2.4 2 1 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_5 PF16770.5 KXH50459.1 - 0.017 15.0 0.0 0.041 13.8 0.0 1.6 1 0 0 1 1 1 0 Regulator of Ty1 transposition protein 107 BRCT domain BRCT_2 PF16589.5 KXH50459.1 - 0.11 13.0 0.0 0.28 11.6 0.0 1.7 1 1 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain BRCT_3 PF18428.1 KXH50459.1 - 0.12 12.5 0.0 24 5.1 0.0 2.6 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain Ecm33 PF12454.8 KXH50459.1 - 0.3 11.3 1.9 0.91 9.7 1.9 1.8 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein Glyco_hydro_16 PF00722.21 KXH50460.1 - 7.8e-12 45.0 0.9 1.2e-11 44.4 0.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Cthe_2159 PF14262.6 KXH50460.1 - 0.052 12.9 0.2 0.081 12.2 0.2 1.3 1 0 0 1 1 1 0 Carbohydrate-binding domain-containing protein Cthe_2159 HET PF06985.11 KXH50461.1 - 4.2e-29 101.8 0.1 7.1e-29 101.0 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Lumazine_bd_2 PF12893.7 KXH50464.1 - 9e-19 68.3 0.0 1e-18 68.1 0.0 1.0 1 0 0 1 1 1 1 Putative lumazine-binding DUF4878 PF12870.7 KXH50464.1 - 0.0012 19.2 0.1 0.003 17.8 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4878) NTF2 PF02136.20 KXH50464.1 - 0.013 16.1 0.0 0.016 15.8 0.0 1.2 1 0 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain CVNH PF08881.10 KXH50465.1 - 1.1e-17 64.6 0.1 1.8e-17 63.9 0.1 1.4 1 0 0 1 1 1 1 CVNH domain SCRL PF06876.12 KXH50465.1 - 2.6 8.3 7.9 9.2 6.5 0.2 3.1 3 0 0 3 3 3 0 Plant self-incompatibility response (SCRL) protein p450 PF00067.22 KXH50466.1 - 8.4e-57 192.9 0.0 2.9e-56 191.1 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 ScsC_N PF18312.1 KXH50466.1 - 0.16 11.8 0.3 0.33 10.8 0.3 1.4 1 0 0 1 1 1 0 Copper resistance protein ScsC N-terminal domain Blt1_C PF17183.4 KXH50468.1 - 0.073 12.7 0.1 0.65 9.6 0.0 2.1 2 0 0 2 2 2 0 Get5 carboxyl domain DUF1989 PF09347.10 KXH50470.1 - 0.13 11.9 0.3 0.4 10.3 0.3 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF1989) WSC PF01822.19 KXH50471.1 - 7.6e-64 211.9 60.9 1.3e-17 63.8 11.0 4.8 4 0 0 4 4 4 4 WSC domain PQQ_3 PF13570.6 KXH50471.1 - 0.013 16.0 7.9 0.5 10.9 0.1 5.3 3 1 0 3 3 3 0 PQQ-like domain Ntox5 PF15543.6 KXH50471.1 - 0.12 12.2 0.1 0.26 11.2 0.1 1.5 1 0 0 1 1 1 0 Bacterial toxin 5 ASH PF15780.5 KXH50471.1 - 1.6 9.0 15.2 2.8 8.2 0.2 4.8 4 1 0 4 4 4 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PQQ PF01011.21 KXH50471.1 - 4.3 7.4 6.0 11 6.2 0.1 4.1 4 0 0 4 4 4 0 PQQ enzyme repeat Macoilin PF09726.9 KXH50473.1 - 1.6 7.2 6.7 2.2 6.7 6.7 1.2 1 0 0 1 1 1 0 Macoilin family p450 PF00067.22 KXH50474.1 - 2.2e-50 171.8 0.0 2.8e-50 171.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KXH50475.1 - 6e-11 41.8 0.0 1.4e-10 40.5 0.0 1.5 2 0 0 2 2 2 1 Cytochrome P450 Peptidase_M43 PF05572.13 KXH50476.1 - 4.8e-16 59.0 0.0 8.6e-16 58.2 0.0 1.5 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.6 KXH50476.1 - 1.5e-05 25.5 0.1 4.1e-05 24.1 0.1 1.8 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 KXH50476.1 - 2.5e-05 24.5 5.2 7.9e-05 22.9 5.2 1.8 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 KXH50476.1 - 0.0018 18.2 0.2 0.0033 17.3 0.2 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KXH50476.1 - 0.0029 17.3 5.0 0.0098 15.6 5.0 1.8 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 KXH50476.1 - 0.0036 17.2 0.0 0.0086 15.9 0.0 1.4 1 1 0 1 1 1 1 Matrixin Peptidase_M54 PF07998.11 KXH50476.1 - 0.13 12.2 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M54 Peptidase_M57 PF12388.8 KXH50476.1 - 1.6 8.3 7.5 7.1 6.2 7.5 2.2 1 1 0 1 1 1 0 Dual-action HEIGH metallo-peptidase CytB6-F_Fe-S PF08802.10 KXH50476.1 - 7.1 6.7 6.7 2.9 8.0 1.5 2.5 2 0 0 2 2 2 0 Cytochrome B6-F complex Fe-S subunit Fungal_trans_2 PF11951.8 KXH50477.1 - 7.3e-09 34.9 0.8 1.1e-08 34.3 0.8 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Methyltransf_23 PF13489.6 KXH50478.1 - 1.2e-22 80.5 0.0 1.9e-22 79.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH50478.1 - 1.1e-09 38.8 0.0 2.5e-09 37.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH50478.1 - 1.3e-09 38.0 0.0 1.9e-08 34.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH50478.1 - 4.3e-07 30.5 0.0 8e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH50478.1 - 3.9e-06 27.5 0.0 2e-05 25.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KXH50478.1 - 0.012 15.1 0.0 0.02 14.4 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase PrmA PF06325.13 KXH50478.1 - 0.02 14.3 0.0 0.041 13.3 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KXH50478.1 - 0.027 14.0 0.0 0.05 13.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain CMAS PF02353.20 KXH50478.1 - 0.037 13.3 0.0 0.064 12.5 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_2 PF00891.18 KXH50478.1 - 0.037 13.3 0.0 0.15 11.3 0.0 1.8 2 0 0 2 2 2 0 O-methyltransferase domain Methyltransf_16 PF10294.9 KXH50478.1 - 0.06 13.1 0.0 0.095 12.4 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase PCMT PF01135.19 KXH50478.1 - 0.23 11.2 0.0 1.3 8.8 0.0 2.0 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 KXH50479.1 - 2.4e-20 73.0 0.0 3.5e-20 72.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH50479.1 - 8.9e-08 32.7 0.0 3.1e-07 31.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH50479.1 - 3.8e-06 26.8 0.0 5.5e-05 23.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH50479.1 - 1.5e-05 25.7 0.0 0.00012 22.8 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH50479.1 - 1.8e-05 25.3 0.0 3.9e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KXH50479.1 - 0.035 13.6 1.0 0.13 11.7 0.0 2.3 3 0 0 3 3 3 0 Putative methyltransferase EXS PF03124.14 KXH50482.1 - 9.9e-103 343.9 28.8 1.2e-102 343.6 28.8 1.1 1 0 0 1 1 1 1 EXS family SPX PF03105.19 KXH50482.1 - 4.7e-88 296.7 8.3 4.7e-88 296.7 8.3 2.7 2 1 0 2 2 2 1 SPX domain DUF883 PF05957.13 KXH50482.1 - 0.58 10.8 2.0 1.1 9.9 0.4 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Peptidase_M18 PF02127.15 KXH50483.1 - 6.7e-124 414.0 0.0 8.1e-124 413.7 0.0 1.1 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Pyr_redox_2 PF07992.14 KXH50484.1 - 1.8e-15 57.0 0.0 1.4e-10 40.9 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXH50484.1 - 8.4e-15 54.8 0.0 1.2e-13 51.0 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KXH50484.1 - 1.9e-13 49.7 0.0 3.4e-13 48.9 0.0 1.3 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KXH50484.1 - 2.6e-13 49.8 0.0 5.2e-09 35.7 0.0 2.3 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KXH50484.1 - 3.3e-06 27.2 0.0 8.8e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXH50484.1 - 0.00015 21.5 0.5 0.064 12.8 0.0 3.1 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KXH50484.1 - 0.00029 21.3 0.1 0.59 10.7 0.0 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KXH50484.1 - 0.00046 19.6 0.4 0.022 14.1 0.0 2.7 2 1 1 3 3 3 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 KXH50484.1 - 0.00054 19.1 3.7 0.095 11.8 0.7 3.0 3 0 0 3 3 3 2 FAD binding domain Thi4 PF01946.17 KXH50484.1 - 0.00088 18.6 0.1 2.7 7.2 0.0 3.2 3 0 0 3 3 3 1 Thi4 family SnoaL_2 PF12680.7 KXH50484.1 - 0.0011 19.5 0.3 0.0052 17.4 0.2 2.2 2 0 0 2 2 2 1 SnoaL-like domain FAD_oxidored PF12831.7 KXH50484.1 - 0.0013 18.2 0.0 0.0021 17.5 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Shikimate_DH PF01488.20 KXH50484.1 - 0.015 15.3 0.0 0.03 14.4 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF4440 PF14534.6 KXH50484.1 - 0.024 15.0 0.6 0.31 11.5 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4440) NAD_binding_9 PF13454.6 KXH50484.1 - 0.027 14.4 1.4 13 5.7 0.1 3.3 3 1 1 4 4 4 0 FAD-NAD(P)-binding SnoaL_3 PF13474.6 KXH50484.1 - 0.072 13.4 0.3 0.23 11.7 0.3 1.9 1 0 0 1 1 1 0 SnoaL-like domain HI0933_like PF03486.14 KXH50484.1 - 0.079 11.6 0.4 0.17 10.6 0.4 1.5 1 0 0 1 1 1 0 HI0933-like protein PAF-AH_p_II PF03403.13 KXH50485.1 - 8.9e-40 136.4 0.0 1.5e-35 122.5 0.0 2.1 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 KXH50485.1 - 0.00015 20.8 0.0 0.00044 19.2 0.0 1.7 2 0 0 2 2 2 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 KXH50485.1 - 0.0048 16.2 0.0 0.07 12.4 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Chlorophyllase PF07224.11 KXH50485.1 - 0.029 13.4 0.0 0.05 12.6 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase Glyco_hydro_28 PF00295.17 KXH50487.1 - 1.7e-36 126.0 2.7 1.3e-33 116.5 1.2 2.1 2 0 0 2 2 2 2 Glycosyl hydrolases family 28 CAF1A PF12253.8 KXH50488.1 - 5.5e-21 74.5 3.6 5.5e-21 74.5 3.6 3.6 2 1 0 2 2 2 1 Chromatin assembly factor 1 subunit A SprA-related PF12118.8 KXH50488.1 - 0.016 14.4 23.8 0.03 13.5 23.8 1.4 1 0 0 1 1 1 0 SprA-related family Hamartin PF04388.12 KXH50488.1 - 0.13 10.9 27.7 0.011 14.5 22.2 1.8 2 0 0 2 2 2 0 Hamartin protein Presenilin PF01080.17 KXH50488.1 - 0.91 8.2 21.8 1.6 7.4 21.8 1.4 1 0 0 1 1 1 0 Presenilin FAM60A PF15396.6 KXH50488.1 - 5.1 7.0 27.2 0.19 11.7 20.4 2.1 2 0 0 2 2 2 0 Protein Family FAM60A ARGLU PF15346.6 KXH50488.1 - 5.5 6.9 45.7 16 5.4 45.7 1.7 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 LAP1C PF05609.12 KXH50488.1 - 9.9 5.1 23.7 0.84 8.7 18.4 1.9 2 0 0 2 2 2 0 Lamina-associated polypeptide 1C (LAP1C) Peptidase_M14 PF00246.24 KXH50509.1 - 1.2e-71 241.8 0.0 1.6e-71 241.5 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase MAPEG PF01124.18 KXH50510.1 - 1.1e-22 80.3 0.2 1.3e-22 80.1 0.2 1.1 1 0 0 1 1 1 1 MAPEG family DNA_pol_B_thumb PF14791.6 KXH50511.1 - 3e-21 75.3 0.0 8.3e-21 73.9 0.0 1.8 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_B_palm PF14792.6 KXH50511.1 - 3.7e-21 75.4 0.0 8.8e-21 74.2 0.0 1.7 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_lambd_f PF10391.9 KXH50511.1 - 1.4e-19 69.6 1.4 1.4e-19 69.6 1.4 2.5 3 0 0 3 3 3 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.6 KXH50511.1 - 1e-11 45.0 0.0 3.2e-11 43.4 0.0 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH_5 PF14520.6 KXH50511.1 - 0.00035 21.1 0.0 0.96 10.1 0.0 2.5 2 0 0 2 2 2 2 Helix-hairpin-helix domain NTP_transf_2 PF01909.23 KXH50511.1 - 0.003 17.8 0.0 0.013 15.7 0.0 2.1 2 0 0 2 2 2 1 Nucleotidyltransferase domain WSK PF03832.13 KXH50511.1 - 0.012 15.3 1.1 0.031 14.0 1.1 1.7 1 0 0 1 1 1 0 WSK motif BRCT_2 PF16589.5 KXH50511.1 - 0.022 15.1 0.0 0.053 13.9 0.0 1.7 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain TFIIE_alpha PF02002.17 KXH50512.1 - 2.2e-14 53.2 0.1 5.2e-14 52.0 0.1 1.6 1 0 0 1 1 1 1 TFIIE alpha subunit zf-Dof PF02701.15 KXH50512.1 - 0.024 14.8 0.5 0.053 13.7 0.5 1.5 1 0 0 1 1 1 0 Dof domain, zinc finger zinc-ribbons_6 PF07191.12 KXH50512.1 - 0.067 13.2 0.1 0.15 12.1 0.1 1.5 1 0 0 1 1 1 0 zinc-ribbons R3H-assoc PF13902.6 KXH50512.1 - 0.17 12.3 6.1 2.7 8.4 3.6 3.0 3 1 0 3 3 3 0 R3H-associated N-terminal domain zf-CCHC_2 PF13696.6 KXH50512.1 - 1.7 8.5 4.5 0.41 10.5 0.5 2.0 2 0 0 2 2 2 0 Zinc knuckle SMC_N PF02463.19 KXH50513.1 - 2.3e-60 203.8 0.2 1.6e-59 201.1 0.2 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KXH50513.1 - 7e-24 84.4 0.0 4.3e-23 81.8 0.0 2.4 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 KXH50513.1 - 4.7e-09 36.5 2.0 5.6e-05 23.1 0.1 4.6 3 3 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KXH50513.1 - 1.1e-07 31.5 0.0 2.2e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 KXH50513.1 - 0.00025 20.9 31.1 0.00025 20.9 31.1 4.4 2 2 0 3 3 2 1 AAA ATPase domain SbcCD_C PF13558.6 KXH50513.1 - 0.012 15.8 0.0 0.083 13.1 0.0 2.6 2 0 0 2 2 1 0 Putative exonuclease SbcCD, C subunit PI-TkoII_IV PF18714.1 KXH50513.1 - 0.035 13.6 2.3 0.075 12.5 0.5 2.5 2 0 0 2 2 2 0 DNA polymerase II intein Domain IV Spc7 PF08317.11 KXH50513.1 - 0.2 10.5 119.3 0.38 9.6 14.0 7.2 3 2 4 7 7 7 0 Spc7 kinetochore protein RIH_assoc PF08454.11 KXH50513.1 - 0.4 10.6 5.6 8.1 6.4 0.1 3.2 3 0 0 3 3 3 0 RyR and IP3R Homology associated DEAD PF00270.29 KXH50513.1 - 0.78 9.5 5.1 14 5.4 0.0 3.6 3 0 0 3 3 3 0 DEAD/DEAH box helicase AAA_13 PF13166.6 KXH50513.1 - 1.9 7.0 95.3 0.59 8.7 18.6 6.8 2 2 3 6 6 6 0 AAA domain DASH_Dam1 PF08653.10 KXH50513.1 - 2.5 8.0 5.6 32 4.4 0.1 4.6 3 1 1 4 4 4 0 DASH complex subunit Dam1 DUF1730 PF08331.10 KXH50513.1 - 2.9 7.9 6.0 2.7 8.0 0.3 3.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1730) DUF1664 PF07889.12 KXH50513.1 - 4.9 7.2 59.9 0.35 10.9 2.5 8.0 5 2 2 8 8 8 0 Protein of unknown function (DUF1664) DUF2838 PF10998.8 KXH50514.1 - 5.5e-45 152.2 9.6 5.5e-45 152.2 9.6 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2838) FAM184 PF15665.5 KXH50514.1 - 0.063 13.0 2.3 0.13 12.0 2.3 1.4 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B Prominin PF05478.11 KXH50514.1 - 0.1 10.6 0.0 0.15 10.0 0.0 1.1 1 0 0 1 1 1 0 Prominin DUF1640 PF07798.11 KXH50514.1 - 0.13 12.3 0.5 0.42 10.6 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) Tropomyosin_1 PF12718.7 KXH50514.1 - 0.48 10.6 2.6 0.32 11.2 0.5 1.7 2 0 0 2 2 2 0 Tropomyosin like WD40 PF00400.32 KXH50515.1 - 7.4e-20 70.9 15.3 0.00039 21.2 0.1 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXH50515.1 - 3.8e-13 49.5 6.1 4.3e-05 23.7 0.5 4.3 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KXH50515.1 - 7.5e-08 32.5 0.1 0.00063 19.7 0.1 2.8 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Importin_rep_4 PF18808.1 KXH50526.1 - 2.2e-32 111.2 9.6 1.8e-31 108.2 2.0 4.7 4 1 1 5 5 4 1 Importin repeat HEAT_EZ PF13513.6 KXH50526.1 - 4.9e-23 81.2 11.7 5.6e-11 42.7 0.3 9.1 6 1 2 8 8 8 3 HEAT-like repeat HEAT PF02985.22 KXH50526.1 - 2.2e-20 71.0 16.9 0.0039 17.3 0.0 12.6 14 0 0 14 14 11 3 HEAT repeat Importin_rep_5 PF18816.1 KXH50526.1 - 3.7e-20 72.0 5.1 7e-20 71.1 1.0 3.4 4 0 0 4 4 3 1 Importin repeat HEAT_2 PF13646.6 KXH50526.1 - 3e-18 66.0 11.5 1.5e-06 28.5 0.1 8.4 5 2 2 7 7 7 3 HEAT repeats Importin_rep_6 PF18829.1 KXH50526.1 - 7.3e-14 51.8 1.7 2.4e-12 46.9 0.1 3.4 3 0 0 3 3 3 1 Importin repeat 6 Vac14_Fab1_bd PF12755.7 KXH50526.1 - 3.2e-13 50.1 0.5 0.0036 17.9 0.0 8.1 6 3 3 10 10 8 2 Vacuolar 14 Fab1-binding region DUF3385 PF11865.8 KXH50526.1 - 2.8e-09 37.1 0.0 0.051 13.5 0.0 6.5 7 1 1 8 8 7 1 Domain of unknown function (DUF3385) DRIM PF07539.12 KXH50526.1 - 3.5e-08 32.2 1.3 0.00028 19.4 0.7 4.0 3 2 1 4 4 4 2 Down-regulated in metastasis RIX1 PF08167.12 KXH50526.1 - 1.6e-07 31.3 0.0 0.00039 20.2 0.0 4.7 3 1 1 4 4 4 2 rRNA processing/ribosome biogenesis Cnd1 PF12717.7 KXH50526.1 - 3.4e-07 30.4 0.6 0.14 12.2 0.0 5.9 5 3 0 5 5 5 1 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 KXH50526.1 - 5.9e-07 29.3 0.6 0.0018 17.9 0.1 5.3 5 1 1 6 6 6 1 CLASP N terminal MMS19_C PF12460.8 KXH50526.1 - 1.4e-06 27.7 4.5 2.8e-06 26.7 0.3 3.6 3 1 0 4 4 4 1 RNAPII transcription regulator C-terminal DUF3535 PF12054.8 KXH50526.1 - 0.00024 20.5 0.4 0.001 18.4 0.4 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3535) Arm PF00514.23 KXH50526.1 - 0.00038 20.4 8.8 1.2 9.3 0.0 5.6 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat DUF4042 PF13251.6 KXH50526.1 - 0.00077 19.2 0.1 8.5 6.0 0.0 4.6 4 0 0 4 4 4 0 Domain of unknown function (DUF4042) UNC45-central PF11701.8 KXH50526.1 - 0.00093 19.2 4.3 0.44 10.5 0.6 4.5 4 1 0 4 4 4 1 Myosin-binding striated muscle assembly central Adaptin_N PF01602.20 KXH50526.1 - 0.0019 16.8 1.6 0.038 12.6 0.5 3.0 2 1 0 2 2 2 1 Adaptin N terminal region RTP1_C1 PF10363.9 KXH50526.1 - 0.004 17.3 1.0 0.32 11.2 0.5 4.3 4 1 2 6 6 6 1 Required for nuclear transport of RNA pol II C-terminus 1 IBN_N PF03810.19 KXH50526.1 - 0.0067 16.3 1.4 0.053 13.5 0.1 3.4 3 1 1 4 4 3 1 Importin-beta N-terminal domain CAS_CSE1 PF03378.15 KXH50526.1 - 0.017 13.6 0.3 7.4 4.9 0.1 3.3 1 1 2 3 3 3 0 CAS/CSE protein, C-terminus DNA_alkylation PF08713.11 KXH50526.1 - 0.04 13.6 0.1 0.46 10.2 0.0 2.7 2 1 1 3 3 2 0 DNA alkylation repair enzyme TFCD_C PF12612.8 KXH50526.1 - 0.04 13.7 0.0 1.8 8.4 0.0 3.2 2 1 0 3 3 3 0 Tubulin folding cofactor D C terminal Xpo1 PF08389.12 KXH50526.1 - 0.081 13.0 0.0 2.3 8.3 0.0 3.0 2 0 0 2 2 2 0 Exportin 1-like protein Telomere_reg-2 PF10193.9 KXH50526.1 - 0.11 13.0 4.9 0.32 11.5 1.9 3.3 3 1 1 4 4 3 0 Telomere length regulation protein V-ATPase_H_N PF03224.14 KXH50526.1 - 0.16 11.3 3.9 0.25 10.6 0.4 2.9 3 1 0 3 3 3 0 V-ATPase subunit H CBS PF00571.28 KXH50527.1 - 8.9e-09 35.7 0.6 6e-07 29.8 0.0 2.9 2 1 0 2 2 2 2 CBS domain Beta_helix PF13229.6 KXH50542.1 - 1.8e-10 40.9 10.6 1.8e-10 40.9 10.6 2.7 2 1 1 3 3 3 2 Right handed beta helix region Chondroitinas_B PF14592.6 KXH50542.1 - 5.3e-06 25.6 0.1 9.6e-06 24.7 0.1 1.3 1 0 0 1 1 1 1 Chondroitinase B DUF1565 PF07602.11 KXH50542.1 - 0.0046 16.3 1.2 0.016 14.6 0.0 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF1565) NmrA PF05368.13 KXH50543.1 - 1.4e-09 37.8 0.0 1.8e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXH50543.1 - 3.9e-08 33.4 0.0 5.5e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding INCENP_ARK-bind PF03941.15 KXH50543.1 - 0.17 11.8 0.0 0.39 10.7 0.0 1.6 1 0 0 1 1 1 0 Inner centromere protein, ARK binding region Peptidase_M14 PF00246.24 KXH50544.1 - 3e-83 279.9 0.2 3.9e-83 279.6 0.2 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.16 KXH50544.1 - 4.1e-05 23.9 0.0 0.00031 21.1 0.0 2.4 3 0 0 3 3 3 1 Carboxypeptidase activation peptide Cellulase PF00150.18 KXH50545.1 - 2.1e-16 60.2 1.3 3.8e-16 59.4 1.3 1.4 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Amidohydro_3 PF07969.11 KXH50546.1 - 7.3e-73 246.6 2.5 8.3e-73 246.4 2.5 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 KXH50546.1 - 9.5e-19 67.9 1.7 8.8e-15 54.9 0.2 2.7 2 1 0 2 2 2 2 Amidohydrolase family Fungal_trans PF04082.18 KXH50547.1 - 1.2e-37 129.4 0.1 1.8e-37 128.9 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH50547.1 - 0.0027 17.8 3.7 0.0045 17.1 3.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF917 PF06032.12 KXH50548.1 - 6.5e-112 373.8 1.8 6.5e-112 373.8 1.8 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF917) Hydantoinase_A PF01968.18 KXH50548.1 - 4.9e-29 101.5 10.6 3.2e-24 85.7 1.0 3.6 2 1 1 3 3 3 2 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 KXH50548.1 - 3.9e-25 88.6 2.5 7.8e-24 84.3 0.2 3.1 3 0 0 3 3 3 1 Hydantoinase/oxoprolinase N-terminal region BcrAD_BadFG PF01869.20 KXH50548.1 - 0.0027 17.3 0.2 0.0027 17.3 0.2 2.5 3 0 0 3 3 3 1 BadF/BadG/BcrA/BcrD ATPase family StbA PF06406.11 KXH50548.1 - 0.4 9.9 2.8 1.5 8.0 0.0 2.8 3 0 0 3 3 3 0 StbA protein COesterase PF00135.28 KXH50550.1 - 7.9e-81 272.5 0.0 6.2e-75 253.0 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 KXH50550.1 - 0.00053 19.9 0.0 0.004 17.0 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF4964 PF16334.5 KXH50550.1 - 0.0075 15.8 0.0 0.016 14.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4964) adh_short PF00106.25 KXH50551.1 - 1.4e-42 145.4 0.0 2e-42 144.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXH50551.1 - 5e-33 114.6 0.0 6.5e-33 114.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH50551.1 - 7.7e-10 39.0 0.0 1.2e-09 38.3 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KXH50551.1 - 0.0021 18.0 0.0 0.0028 17.6 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KXH50551.1 - 0.0066 15.9 0.0 0.022 14.2 0.0 1.9 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.8 KXH50551.1 - 0.0077 16.0 0.2 0.019 14.7 0.0 1.7 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1776 PF08643.10 KXH50551.1 - 0.012 15.0 0.0 0.016 14.6 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) UxaE PF16257.5 KXH50551.1 - 0.056 12.1 0.0 0.081 11.6 0.0 1.2 1 0 0 1 1 1 0 tagaturonate epimerase RmlD_sub_bind PF04321.17 KXH50551.1 - 0.063 12.4 0.0 0.11 11.6 0.0 1.4 1 1 0 1 1 1 0 RmlD substrate binding domain CFEM PF05730.11 KXH50552.1 - 9.9e-16 57.6 14.2 1.6e-15 56.9 14.2 1.3 1 0 0 1 1 1 1 CFEM domain Fungal_trans PF04082.18 KXH50553.1 - 7.9e-08 31.7 0.0 1.7e-07 30.6 0.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH50553.1 - 1.7e-07 31.2 10.3 3.3e-07 30.3 10.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 KXH50554.1 - 1e-27 97.0 51.7 1.7e-25 89.7 38.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily APOC4 PF15119.6 KXH50554.1 - 0.001 19.3 0.0 0.0019 18.4 0.0 1.4 1 0 0 1 1 1 1 Apolipoprotein C4 DUF5345 PF17280.2 KXH50554.1 - 0.47 10.5 5.0 4.6 7.3 2.9 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF5345) GFO_IDH_MocA PF01408.22 KXH50556.1 - 3.4e-05 24.7 0.0 0.00012 22.8 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold NADH_B2 PF14813.6 KXH50556.1 - 0.083 12.7 0.1 0.21 11.4 0.1 1.6 1 0 0 1 1 1 0 NADH dehydrogenase 1 beta subcomplex subunit 2 adh_short PF00106.25 KXH50557.1 - 2.5e-27 95.6 0.0 4.9e-27 94.7 0.0 1.4 1 1 1 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXH50557.1 - 7.7e-21 74.7 0.3 9.6e-21 74.4 0.3 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH50557.1 - 1.6e-11 44.4 0.0 2.3e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXH50557.1 - 5.8e-07 29.2 0.0 8.4e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KXH50557.1 - 5.4e-05 23.2 0.1 7.1e-05 22.8 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KXH50557.1 - 0.013 15.8 0.1 0.18 12.1 0.1 2.3 1 1 1 2 2 2 0 Saccharopine dehydrogenase NADP binding domain MFS_1 PF07690.16 KXH50558.1 - 3e-32 111.9 56.8 7.3e-24 84.3 29.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Ank_2 PF12796.7 KXH50559.1 - 1e-19 70.9 1.5 2.4e-15 56.9 0.5 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXH50559.1 - 2.9e-17 62.8 1.8 1.7e-08 34.8 0.2 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXH50559.1 - 2.6e-15 55.0 1.3 0.00045 20.5 0.0 3.3 3 0 0 3 3 3 3 Ankyrin repeat Ank PF00023.30 KXH50559.1 - 3e-14 52.7 3.5 0.00034 20.9 0.1 3.4 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 KXH50559.1 - 1.9e-10 40.8 2.9 8.8e-05 22.7 0.1 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Aminotran_3 PF00202.21 KXH50560.1 - 1.1e-82 277.8 0.0 1.5e-82 277.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 KXH50560.1 - 0.069 12.3 0.1 0.23 10.6 0.0 1.7 2 0 0 2 2 2 0 Aminotransferase class I and II p450 PF00067.22 KXH50561.1 - 2.7e-35 122.0 0.0 3.7e-35 121.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ATPgrasp_N PF18130.1 KXH50562.1 - 2.2e-17 63.4 0.0 5.2e-17 62.2 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp N-terminal domain ATP-grasp_4 PF13535.6 KXH50562.1 - 1.4e-09 37.8 0.0 5.2e-09 35.9 0.0 2.0 1 1 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 KXH50562.1 - 0.0016 18.0 0.0 0.0036 16.8 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Dala_Dala_lig_C PF07478.13 KXH50562.1 - 0.0027 17.3 0.0 0.006 16.1 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 KXH50562.1 - 0.0071 16.4 0.0 0.2 11.7 0.0 2.2 2 0 0 2 2 2 1 ATP-grasp domain GSH-S_ATP PF02955.16 KXH50562.1 - 0.038 13.4 0.0 0.063 12.7 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, ATP-grasp domain GARS_A PF01071.19 KXH50562.1 - 0.13 12.0 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Fungal_trans_2 PF11951.8 KXH50563.1 - 5.6e-40 137.3 0.8 6.8e-40 137.1 0.8 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH50563.1 - 4.5e-07 29.9 13.0 7.7e-07 29.1 13.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DNA_pol3_tau_4 PF12168.8 KXH50563.1 - 0.57 10.8 2.5 1.5 9.4 1.6 2.0 2 0 0 2 2 2 0 DNA polymerase III subunits tau domain IV DnaB-binding MFS_1 PF07690.16 KXH50564.1 - 1e-38 133.2 51.6 4.9e-38 131.0 50.4 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily MFS_1 PF07690.16 KXH50565.1 - 1.4e-49 168.9 52.5 4.2e-49 167.4 51.2 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KXH50565.1 - 1.1e-15 57.1 21.3 1.6e-15 56.5 21.3 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KXH50565.1 - 1.4e-12 47.2 10.0 1.4e-12 47.2 10.0 3.3 2 1 1 3 3 3 1 Sugar (and other) transporter DUF4181 PF13789.6 KXH50565.1 - 0.33 11.2 5.2 0.12 12.7 0.6 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4181) Mur_ligase_C PF02875.21 KXH50566.1 - 0.061 13.6 0.0 4.1 7.7 0.0 3.1 3 0 0 3 3 3 0 Mur ligase family, glutamate ligase domain Mur_ligase_M PF08245.12 KXH50567.1 - 0.00056 20.0 0.1 0.0026 17.8 0.1 1.9 1 1 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 KXH50567.1 - 0.0075 16.5 0.0 0.017 15.4 0.0 1.6 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain GPHH PF16905.5 KXH50567.1 - 0.19 11.5 0.0 0.79 9.5 0.0 2.0 2 0 0 2 2 2 0 Voltage-dependent L-type calcium channel, IQ-associated Mitofilin PF09731.9 KXH50568.1 - 2.7e-146 489.0 25.8 2.3e-123 413.2 21.6 2.1 2 0 0 2 2 2 2 Mitochondrial inner membrane protein DUF3496 PF12001.8 KXH50568.1 - 0.037 14.4 4.1 0.11 12.9 4.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3496) DUF1848 PF08902.11 KXH50568.1 - 0.31 10.7 1.4 0.38 10.4 0.6 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1848) HsbA PF12296.8 KXH50568.1 - 0.71 10.3 4.9 1.8 9.0 0.3 3.2 3 0 0 3 3 3 0 Hydrophobic surface binding protein A YlqD PF11068.8 KXH50568.1 - 1.3 9.4 9.0 5.3 7.4 5.1 2.4 1 1 1 2 2 2 0 YlqD protein Amidase PF01425.21 KXH50574.1 - 3.3e-10 39.5 0.0 6.7e-10 38.5 0.0 1.4 1 1 0 1 1 1 1 Amidase DUF3759 PF12585.8 KXH50575.1 - 2 8.5 10.1 0.21 11.7 4.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3759) GATA PF00320.27 KXH50576.1 - 4.6e-16 58.1 5.4 9.5e-16 57.1 5.4 1.6 1 0 0 1 1 1 1 GATA zinc finger PAS_3 PF08447.12 KXH50576.1 - 1.1e-13 51.2 0.0 2.6e-13 50.1 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 KXH50576.1 - 6.5e-07 29.4 0.1 1.8e-06 27.9 0.0 1.7 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 KXH50576.1 - 9.1e-05 22.7 0.1 0.00035 20.8 0.0 1.9 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.10 KXH50576.1 - 0.00096 19.4 0.0 0.0018 18.5 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_11 PF14598.6 KXH50576.1 - 0.0039 17.3 0.0 0.0081 16.3 0.0 1.5 1 0 0 1 1 1 1 PAS domain Zn-ribbon_8 PF09723.10 KXH50576.1 - 0.0083 16.2 0.2 0.019 15.1 0.2 1.6 1 0 0 1 1 1 1 Zinc ribbon domain TF_Zn_Ribbon PF08271.12 KXH50576.1 - 0.097 12.2 0.6 0.68 9.5 0.1 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding DUF4428 PF14471.6 KXH50576.1 - 4 7.4 7.5 0.85 9.6 1.3 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4428) AAA_23 PF13476.6 KXH50577.1 - 1.5e-34 120.3 1.8 1.5e-34 120.3 1.8 7.2 1 1 4 5 5 3 1 AAA domain AAA_21 PF13304.6 KXH50577.1 - 4.2e-10 39.9 7.6 0.0002 21.3 3.0 3.8 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 KXH50577.1 - 7.1e-07 29.4 0.0 2.4e-06 27.7 0.0 2.0 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.6 KXH50577.1 - 0.00017 21.4 8.3 0.00017 21.4 8.3 5.9 1 1 1 4 4 4 2 AAA ATPase domain AAA_29 PF13555.6 KXH50577.1 - 0.0016 18.1 0.0 0.0035 17.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain HCMV_UL139 PF12507.8 KXH50577.1 - 0.0052 17.2 0.0 0.0052 17.2 0.0 5.3 5 3 0 5 5 5 1 Human Cytomegalovirus UL139 protein KxDL PF10241.9 KXH50577.1 - 0.056 13.7 0.3 0.056 13.7 0.3 9.2 7 3 2 9 9 9 0 Uncharacterized conserved protein AAA_13 PF13166.6 KXH50577.1 - 0.072 11.7 0.1 0.072 11.7 0.1 6.9 2 1 5 7 7 7 0 AAA domain AAA_16 PF13191.6 KXH50577.1 - 0.086 13.2 0.0 0.086 13.2 0.0 4.4 4 1 0 4 4 4 0 AAA ATPase domain ABC_tran PF00005.27 KXH50577.1 - 0.11 13.0 0.0 0.11 13.0 0.0 6.5 3 2 1 4 4 2 0 ABC transporter SMC_N PF02463.19 KXH50577.1 - 2.3 7.6 64.5 25 4.2 64.5 2.6 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain Strep_SA_rep PF06696.11 KXH50577.1 - 3.1 7.9 8.4 4 7.6 3.1 3.0 2 0 0 2 2 2 0 Streptococcal surface antigen repeat PPP4R2 PF09184.11 KXH50578.1 - 1.2e-14 54.6 11.6 5.8e-13 49.1 0.0 3.0 2 1 1 3 3 3 1 PPP4R2 RRF PF01765.19 KXH50579.1 - 2.6e-24 86.0 4.0 3.6e-24 85.6 4.0 1.2 1 0 0 1 1 1 1 Ribosome recycling factor IMS PF00817.20 KXH50634.1 - 1.4e-39 135.5 0.0 2.8e-39 134.5 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 KXH50634.1 - 1.4e-14 54.8 0.0 3e-14 53.7 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain zf_UBZ PF18439.1 KXH50634.1 - 8.7e-13 47.6 2.1 1.8e-12 46.6 2.1 1.6 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger IMS_HHH PF11798.8 KXH50634.1 - 0.013 15.8 0.1 0.15 12.4 0.0 2.5 2 0 0 2 2 2 0 IMS family HHH motif RAP1 PF07218.11 KXH50634.1 - 0.75 8.0 1.7 1.2 7.3 1.7 1.4 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DHHC PF01529.20 KXH50636.1 - 1.2e-25 90.2 0.9 1.2e-25 90.2 0.9 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase IBR PF01485.21 KXH50637.1 - 0.0068 16.6 4.1 0.012 15.8 4.1 1.4 1 0 0 1 1 1 1 IBR domain, a half RING-finger domain SET PF00856.28 KXH50639.1 - 4.3e-16 59.7 3.1 8.9e-16 58.7 0.6 2.7 2 1 0 2 2 2 1 SET domain AWS PF17907.1 KXH50639.1 - 4.3e-06 26.7 7.6 4.3e-06 26.7 7.6 2.3 2 0 0 2 2 2 1 AWS domain CRAL_TRIO PF00650.20 KXH50640.1 - 1.7e-11 44.1 0.0 2.4e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KXH50640.1 - 2.7e-06 27.5 0.0 5.5e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain RRM_1 PF00076.22 KXH50641.1 - 0.078 12.8 0.0 0.22 11.3 0.0 1.8 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3435 PF11917.8 KXH50844.1 - 1.5e-22 80.2 0.0 2.3e-22 79.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) Chromo PF00385.24 KXH50844.1 - 5e-12 45.5 4.5 1.6e-07 31.1 0.4 2.8 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain zf-C2H2_4 PF13894.6 KXH50844.1 - 4.4 8.4 9.5 65 4.8 0.1 4.2 3 0 0 3 3 3 0 C2H2-type zinc finger HeH PF12949.7 KXH50845.1 - 1.9e-07 30.6 0.2 1.9e-07 30.6 0.2 1.9 2 0 0 2 2 2 1 HeH/LEM domain DUF1664 PF07889.12 KXH50845.1 - 0.035 14.1 62.7 0.063 13.3 1.0 9.9 6 2 5 11 11 11 0 Protein of unknown function (DUF1664) DUF3138 PF11336.8 KXH50845.1 - 2 6.9 9.8 0.35 9.4 4.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3138) FlaC_arch PF05377.11 KXH50845.1 - 3 8.3 21.9 1e+02 3.4 0.5 9.5 9 1 0 9 9 9 0 Flagella accessory protein C (FlaC) HALZ PF02183.18 KXH50845.1 - 7.6 6.8 21.8 0.097 12.9 0.2 5.8 5 0 0 5 5 5 0 Homeobox associated leucine zipper GBP PF02263.19 KXH50846.1 - 0.023 14.0 0.0 0.2 10.9 0.0 2.0 2 0 0 2 2 2 0 Guanylate-binding protein, N-terminal domain Glyco_hydro_cc PF11790.8 KXH50847.1 - 1.4e-52 178.7 0.0 1.6e-52 178.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core F-box-like PF12937.7 KXH50849.1 - 4.3e-09 36.1 0.8 1.2e-08 34.7 0.3 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KXH50849.1 - 0.00028 20.7 1.3 0.00082 19.2 0.1 2.4 2 1 1 3 3 3 1 F-box domain Ank_2 PF12796.7 KXH50856.1 - 3.7e-07 30.6 0.0 1e-05 26.0 0.0 2.9 2 1 1 3 3 3 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXH50856.1 - 6.1e-07 29.3 0.1 2.1 9.2 0.0 5.6 5 0 0 5 5 5 1 Ankyrin repeat Ank PF00023.30 KXH50856.1 - 0.0053 17.1 1.4 7.1 7.3 0.0 3.9 5 0 0 5 5 5 2 Ankyrin repeat Ank_4 PF13637.6 KXH50856.1 - 0.015 15.9 0.4 19 5.9 0.0 4.6 3 1 2 5 5 5 0 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXH50856.1 - 0.016 15.5 0.0 0.21 11.9 0.0 2.8 2 1 0 2 2 2 0 Ankyrin repeats (many copies) F-box PF00646.33 KXH50856.1 - 0.044 13.7 0.1 0.18 11.7 0.1 2.0 1 0 0 1 1 1 0 F-box domain DUF2013 PF09431.10 KXH50864.1 - 5.7e-52 175.6 1.6 5.7e-52 175.6 1.6 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2013) IBN_N PF03810.19 KXH50864.1 - 0.0073 16.2 0.4 0.14 12.1 0.1 2.5 2 0 0 2 2 2 1 Importin-beta N-terminal domain PH PF00169.29 KXH50865.1 - 0.00011 22.7 0.1 0.00028 21.4 0.1 1.8 1 0 0 1 1 1 1 PH domain WEMBL PF05701.11 KXH50865.1 - 0.14 10.8 2.1 0.22 10.1 2.1 1.2 1 0 0 1 1 1 0 Weak chloroplast movement under blue light Prominin PF05478.11 KXH50865.1 - 0.31 9.0 0.1 0.44 8.4 0.1 1.1 1 0 0 1 1 1 0 Prominin MFS_1 PF07690.16 KXH50866.1 - 1.8e-26 93.0 50.3 1.8e-26 93.0 50.3 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily Zip PF02535.22 KXH50866.1 - 2.9 7.0 9.8 11 5.2 0.3 2.4 2 0 0 2 2 2 0 ZIP Zinc transporter Gar1 PF04410.14 KXH50867.1 - 1.7e-34 118.8 0.1 2.5e-34 118.3 0.1 1.2 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region tRNA-synt_2b PF00587.25 KXH50868.1 - 9.7e-31 107.1 0.0 7.5e-29 101.0 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KXH50868.1 - 3.5e-21 75.2 0.3 7e-21 74.2 0.3 1.5 1 0 0 1 1 1 1 Anticodon binding domain TGS PF02824.21 KXH50868.1 - 4.1e-11 42.8 0.0 1e-10 41.5 0.0 1.7 1 0 0 1 1 1 1 TGS domain tRNA_SAD PF07973.14 KXH50868.1 - 6.4e-11 42.2 0.0 1.6e-10 40.9 0.0 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain PepSY_like PF11396.8 KXH50868.1 - 0.031 14.8 0.5 0.4 11.3 0.1 2.8 3 0 0 3 3 3 0 Putative beta-lactamase-inhibitor-like, PepSY-like CDP-OH_P_transf PF01066.21 KXH50869.1 - 2.4e-13 50.6 0.3 6.2e-13 49.3 0.3 1.7 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase Metallopep PF12044.8 KXH50870.1 - 5.7e-169 562.2 0.0 7.2e-169 561.9 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family Jacalin PF01419.17 KXH50870.1 - 4.2e-05 23.5 0.0 7.8e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Jacalin-like lectin domain Reprolysin_5 PF13688.6 KXH50870.1 - 0.0023 18.1 0.2 0.005 17.0 0.2 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12 Whi5 PF08528.11 KXH50871.1 - 1.2e-10 40.7 0.2 2.2e-10 39.9 0.2 1.4 1 0 0 1 1 1 1 Whi5 like HEM4 PF02602.15 KXH50872.1 - 2.7e-39 134.9 0.0 3.7e-39 134.4 0.0 1.1 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD Evr1_Alr PF04777.13 KXH50873.1 - 3.5e-32 110.9 0.4 2.1e-31 108.4 0.4 1.9 2 0 0 2 2 2 1 Erv1 / Alr family GP11 PF08677.10 KXH50873.1 - 0.15 11.5 0.0 0.2 11.1 0.0 1.1 1 0 0 1 1 1 0 GP11 baseplate wedge protein CotE PF10628.9 KXH50873.1 - 0.18 11.4 0.0 0.26 10.9 0.0 1.2 1 0 0 1 1 1 0 Outer spore coat protein E (CotE) DDE_Tnp_ISL3 PF01610.17 KXH50873.1 - 0.18 11.5 0.0 0.23 11.1 0.0 1.1 1 0 0 1 1 1 0 Transposase TPP_enzyme_N PF02776.18 KXH50874.1 - 1.3e-33 116.0 0.0 2.4e-33 115.2 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 KXH50874.1 - 1.6e-22 79.7 0.0 3.5e-22 78.6 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 KXH50874.1 - 8.1e-16 58.2 0.1 6.2e-15 55.3 0.1 2.3 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.6 KXH50874.1 - 0.0043 16.3 0.0 0.0069 15.6 0.0 1.2 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.20 KXH50874.1 - 0.012 14.6 0.0 0.02 13.8 0.0 1.3 1 0 0 1 1 1 0 Dehydrogenase E1 component OCC1 PF15506.6 KXH50874.1 - 0.06 13.5 2.1 8.3 6.6 0.1 3.1 3 0 0 3 3 3 0 OCC1 family THUMP PF02926.17 KXH50875.1 - 2.5e-06 27.7 0.7 2e-05 24.7 0.2 2.5 1 1 1 2 2 2 1 THUMP domain SGT1 PF07093.11 KXH50877.1 - 4.2e-96 322.7 9.6 9.6e-87 291.8 0.0 2.0 2 0 0 2 2 2 2 SGT1 protein DUF5075 PF16825.5 KXH50877.1 - 0.062 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 IGP family C-type lectin domain SMC_N PF02463.19 KXH50878.1 - 3.2e-22 79.0 3.7 1.8e-21 76.6 3.7 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KXH50878.1 - 2.9e-18 67.1 0.1 2.9e-18 67.1 0.1 4.7 2 2 0 3 3 3 1 AAA domain AAA_15 PF13175.6 KXH50878.1 - 5.5e-12 46.1 0.3 5.5e-12 46.1 0.3 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 KXH50878.1 - 1.1e-06 28.8 0.2 9e-05 22.4 0.1 2.8 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system IFT57 PF10498.9 KXH50878.1 - 0.002 17.1 5.3 0.002 17.1 5.3 5.5 3 2 3 6 6 6 3 Intra-flagellar transport protein 57 AAA_29 PF13555.6 KXH50878.1 - 0.004 16.9 0.0 0.0096 15.6 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_hinge PF06470.13 KXH50878.1 - 0.022 15.0 0.0 0.063 13.6 0.0 1.9 1 0 0 1 1 1 0 SMC proteins Flexible Hinge Domain SbcCD_C PF13558.6 KXH50878.1 - 0.047 13.9 0.0 0.14 12.4 0.0 1.8 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.6 KXH50878.1 - 0.23 11.8 1.5 1.6 9.0 0.0 3.1 2 1 0 2 2 2 0 AAA domain DUF1664 PF07889.12 KXH50878.1 - 0.35 10.9 37.7 0.25 11.4 0.8 6.6 4 2 2 6 6 6 0 Protein of unknown function (DUF1664) COQ9 PF08511.11 KXH50879.1 - 9.6e-32 108.6 0.0 1.5e-31 108.0 0.0 1.3 1 0 0 1 1 1 1 COQ9 CPBP PF02517.16 KXH50883.1 - 1.8e-12 47.4 14.0 1.8e-12 47.4 14.0 2.7 2 1 0 2 2 2 1 CPBP intramembrane metalloprotease MMM1 PF10296.9 KXH50884.1 - 6.4e-142 472.5 0.2 2e-140 467.6 0.2 2.0 1 1 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 DUF3981 PF13139.6 KXH50884.1 - 0.18 12.2 0.0 0.35 11.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3981) Sec1 PF00995.23 KXH50885.1 - 1.7e-135 453.5 0.0 2.1e-135 453.2 0.0 1.1 1 0 0 1 1 1 1 Sec1 family Nup84_Nup100 PF04121.13 KXH50885.1 - 0.18 9.9 1.8 0.11 10.6 0.1 1.5 2 0 0 2 2 2 0 Nuclear pore protein 84 / 107 GIDA PF01134.22 KXH50886.1 - 6.3e-159 529.2 0.0 8e-159 528.9 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 KXH50886.1 - 1.7e-67 227.7 0.0 2.8e-67 227.0 0.0 1.3 1 0 0 1 1 1 1 GidA associated domain FAD_oxidored PF12831.7 KXH50886.1 - 1.9e-06 27.5 0.5 3.2e-06 26.8 0.5 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXH50886.1 - 6.4e-06 25.6 0.7 4.1e-05 23.0 0.9 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXH50886.1 - 0.00081 18.6 2.4 0.00081 18.6 2.4 2.0 3 0 0 3 3 3 1 FAD binding domain AlaDh_PNT_C PF01262.21 KXH50886.1 - 0.0029 16.9 0.6 0.0029 16.9 0.6 2.1 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 KXH50886.1 - 0.075 13.6 0.4 0.24 12.0 0.4 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 KXH50886.1 - 0.075 13.5 0.1 0.17 12.3 0.1 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding DAO PF01266.24 KXH50886.1 - 0.27 10.8 1.8 16 4.9 0.0 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.14 KXH50886.1 - 0.44 9.2 6.8 0.32 9.6 0.9 2.4 3 0 0 3 3 3 0 HI0933-like protein CDP-OH_P_transf PF01066.21 KXH50887.1 - 1.9e-15 57.4 0.3 1.9e-15 57.4 0.3 2.5 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Gti1_Pac2 PF09729.9 KXH50888.1 - 4.5e-61 206.1 0.0 6.9e-61 205.5 0.0 1.3 1 0 0 1 1 1 1 Gti1/Pac2 family dCMP_cyt_deam_1 PF00383.23 KXH50897.1 - 8.3e-08 32.0 0.0 1.2e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KXH50897.1 - 2.5e-05 24.0 0.0 6.3e-05 22.7 0.0 1.6 1 1 0 1 1 1 1 MafB19-like deaminase Methyltransf_16 PF10294.9 KXH50898.1 - 4.8e-26 91.6 0.0 7.3e-26 90.9 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 KXH50898.1 - 1.5e-05 24.9 0.0 2.5e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH50898.1 - 0.00067 20.3 0.0 0.0015 19.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 KXH50899.1 - 1.8e-22 79.7 0.0 2.3e-22 79.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXH50899.1 - 1.4e-14 54.2 0.0 1.8e-14 53.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH50899.1 - 1.2e-09 38.4 0.0 1.6e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXH50899.1 - 6e-05 22.6 0.0 0.00012 21.6 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KXH50899.1 - 0.013 15.4 0.2 0.02 14.8 0.2 1.3 1 0 0 1 1 1 0 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KXH50899.1 - 0.13 11.6 0.1 0.3 10.4 0.1 1.7 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase Galactosyl_T PF01762.21 KXH50901.1 - 2.1e-14 53.8 1.8 8.3e-14 51.9 1.8 1.8 1 1 0 1 1 1 1 Galactosyltransferase PBP PF01161.20 KXH50902.1 - 1.4e-16 61.0 0.0 1.8e-16 60.6 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein p450 PF00067.22 KXH50905.1 - 5.9e-51 173.7 0.0 1e-50 172.9 0.0 1.2 1 1 0 1 1 1 1 Cytochrome P450 zf-C2HC_2 PF13913.6 KXH50905.1 - 0.38 10.7 0.7 2.4 8.1 0.1 2.6 3 0 0 3 3 3 0 zinc-finger of a C2HC-type Lactamase_B_2 PF12706.7 KXH50906.1 - 1.4e-06 28.0 0.0 2.3e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KXH50906.1 - 3e-06 27.2 0.0 1.8e-05 24.7 0.0 2.0 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KXH50906.1 - 6.5e-06 26.3 0.1 1.1e-05 25.5 0.1 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily FAD_binding_3 PF01494.19 KXH50907.1 - 5.3e-10 39.1 0.0 9e-10 38.3 0.0 1.3 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KXH50907.1 - 0.0036 16.6 0.0 0.0074 15.6 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXH50907.1 - 0.0066 16.6 0.0 0.016 15.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KXH50907.1 - 0.06 12.4 0.1 0.26 10.3 0.0 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein GIDA PF01134.22 KXH50907.1 - 0.12 11.4 0.0 0.17 11.0 0.0 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A Fungal_trans PF04082.18 KXH50908.1 - 2.4e-09 36.6 0.4 4.8e-09 35.6 0.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH50908.1 - 5.2e-05 23.3 10.9 5.2e-05 23.3 10.9 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dioxygenase_C PF00775.21 KXH50909.1 - 2.6e-06 27.0 0.0 4.3e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Dioxygenase DUF5453 PF17534.2 KXH50910.1 - 0.17 11.9 0.2 0.33 10.9 0.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5453) DAO PF01266.24 KXH50911.1 - 3.3e-48 165.1 1.2 4e-48 164.8 1.2 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXH50911.1 - 0.0032 17.7 0.1 0.01 16.0 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KXH50911.1 - 0.0037 17.3 0.1 0.27 11.2 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding MCRA PF06100.11 KXH50911.1 - 0.0037 16.1 0.0 0.0052 15.6 0.0 1.2 1 0 0 1 1 1 1 MCRA family Pyr_redox_3 PF13738.6 KXH50911.1 - 0.046 13.0 0.0 0.12 11.6 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXH50911.1 - 0.05 12.7 0.8 0.73 8.8 0.0 2.4 2 1 0 2 2 2 0 FAD binding domain Pyr_redox_2 PF07992.14 KXH50911.1 - 0.093 11.9 0.0 2 7.5 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_23 PF13489.6 KXH50913.1 - 2.2e-21 76.4 0.0 4.5e-21 75.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH50913.1 - 1.4e-12 48.1 0.0 3.5e-12 46.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH50913.1 - 1.5e-11 44.8 0.0 3.7e-11 43.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH50913.1 - 2.6e-11 43.5 0.0 2e-10 40.7 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH50913.1 - 2.9e-11 44.0 0.0 6.9e-11 42.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXH50913.1 - 2e-06 27.4 0.0 6.2e-06 25.7 0.0 1.7 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.19 KXH50913.1 - 0.00019 21.6 0.0 0.00033 20.8 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_4 PF02390.17 KXH50913.1 - 0.001 18.5 0.0 0.0029 17.1 0.0 1.7 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.14 KXH50913.1 - 0.22 11.1 0.0 0.51 9.9 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase small domain Glyco_transf_5 PF08323.11 KXH50914.1 - 8.5e-16 58.4 0.1 1.9e-15 57.2 0.1 1.6 1 0 0 1 1 1 1 Starch synthase catalytic domain Alpha-amylase PF00128.24 KXH50914.1 - 2.4e-13 50.4 1.8 2.4e-13 50.4 1.8 3.0 2 1 0 2 2 2 1 Alpha amylase, catalytic domain Glycos_transf_1 PF00534.20 KXH50914.1 - 9.3e-05 22.0 0.0 0.00018 21.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Cupin_2 PF07883.11 KXH50916.1 - 3e-10 39.7 0.1 4.4e-10 39.1 0.1 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 KXH50916.1 - 0.0069 16.0 0.1 0.0099 15.6 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF861) HgmA PF04209.13 KXH50917.1 - 1e-189 630.7 0.1 1.2e-189 630.4 0.1 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase DUF3663 PF12404.8 KXH50918.1 - 0.057 13.5 0.0 0.17 12.0 0.0 1.8 1 1 0 1 1 1 0 Peptidase PIF6 PF05341.11 KXH50918.1 - 0.081 13.1 0.1 6.2 7.0 0.0 2.1 2 0 0 2 2 2 0 Per os infectivity factor 6 CN_hydrolase PF00795.22 KXH50919.1 - 2.5e-30 105.7 0.0 3.4e-30 105.3 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.17 KXH50919.1 - 1e-22 80.5 0.0 3.3e-22 78.8 0.0 1.8 1 1 0 1 1 1 1 NAD synthase Asn_synthase PF00733.21 KXH50919.1 - 0.0004 20.1 0.1 0.00075 19.3 0.1 1.3 1 0 0 1 1 1 1 Asparagine synthase Kelch_5 PF13854.6 KXH50920.1 - 8.3e-20 70.4 0.3 0.0059 16.6 0.0 5.4 5 0 0 5 5 5 5 Kelch motif Kelch_4 PF13418.6 KXH50920.1 - 3.5e-17 62.1 2.7 2.7e-07 30.5 0.0 5.0 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_3 PF13415.6 KXH50920.1 - 8.9e-15 54.6 6.8 1.6e-07 31.5 0.0 5.5 6 1 0 6 6 6 2 Galactose oxidase, central domain Kelch_6 PF13964.6 KXH50920.1 - 1.3e-10 41.2 0.6 0.12 12.7 0.0 4.2 3 1 1 4 4 4 3 Kelch motif Kelch_2 PF07646.15 KXH50920.1 - 5.8e-06 26.1 2.1 0.014 15.4 0.0 4.4 4 1 1 5 5 5 2 Kelch motif Kelch_1 PF01344.25 KXH50920.1 - 4.1e-05 23.1 0.8 5.9 6.6 0.0 4.6 4 0 0 4 4 4 2 Kelch motif Mannosyl_trans3 PF11051.8 KXH50921.1 - 0.012 14.9 0.0 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 Mannosyltransferase putative DUF3328 PF11807.8 KXH50923.1 - 1.8e-25 90.0 0.9 2.6e-25 89.5 0.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) TauD PF02668.16 KXH50924.1 - 5.3e-62 210.0 0.7 6.7e-62 209.7 0.7 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.16 KXH50925.1 - 2.4e-16 59.6 22.7 2.4e-16 59.6 22.7 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily V_ATPase_I PF01496.19 KXH50925.1 - 0.042 11.8 0.0 0.062 11.2 0.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMEM132D_C PF15706.5 KXH50925.1 - 0.13 12.0 0.1 1.2 9.0 0.0 2.2 2 0 0 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term DUF1310 PF07006.11 KXH50927.1 - 0.071 13.1 0.0 0.45 10.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1310) PGC7_Stella PF15549.6 KXH50927.1 - 1.3 9.0 5.7 0.61 10.1 2.9 1.8 1 1 1 2 2 2 0 PGC7/Stella/Dppa3 domain NB-ARC PF00931.22 KXH50928.1 - 4.6e-12 45.7 0.0 9.5e-12 44.6 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain TPR_12 PF13424.6 KXH50928.1 - 1.6e-06 28.3 9.3 0.0022 18.3 0.2 4.1 3 1 1 4 4 4 2 Tetratricopeptide repeat AAA_16 PF13191.6 KXH50928.1 - 3.1e-06 27.7 3.4 0.00019 21.9 0.0 3.6 3 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 KXH50928.1 - 0.0003 21.1 0.0 0.0016 18.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 KXH50928.1 - 0.0028 17.6 0.8 0.0095 15.9 0.0 2.1 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea NACHT PF05729.12 KXH50928.1 - 0.009 15.9 0.0 0.026 14.4 0.0 1.8 1 0 0 1 1 1 1 NACHT domain zf-Di19 PF05605.12 KXH50928.1 - 0.78 10.1 3.1 14 6.0 0.6 2.6 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Acetyltransf_1 PF00583.25 KXH50929.1 - 3.8e-06 27.1 0.2 6.7e-06 26.3 0.2 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXH50929.1 - 0.00023 21.1 0.0 0.00061 19.7 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXH50929.1 - 0.00037 20.9 0.0 0.00078 19.8 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Pyr_redox_2 PF07992.14 KXH50930.1 - 1.6e-36 126.0 0.2 2.3e-36 125.5 0.2 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXH50930.1 - 1.6e-11 44.6 1.0 2.8e-10 40.6 0.1 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXH50930.1 - 1.3e-05 24.6 0.0 2.2e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXH50930.1 - 8.6e-05 21.8 0.1 0.00016 20.9 0.1 1.4 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.12 KXH50930.1 - 0.00073 18.7 0.2 0.0067 15.5 0.1 2.5 3 0 0 3 3 3 1 Lycopene cyclase protein Trp_halogenase PF04820.14 KXH50930.1 - 0.0012 17.8 0.3 4.1 6.2 0.0 3.0 2 1 1 3 3 3 2 Tryptophan halogenase HI0933_like PF03486.14 KXH50930.1 - 0.0017 17.1 6.4 0.15 10.7 0.0 3.4 3 1 1 4 4 4 2 HI0933-like protein DAO PF01266.24 KXH50930.1 - 0.013 15.1 1.0 1.4 8.5 0.0 3.2 3 1 1 4 4 4 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KXH50930.1 - 0.029 14.4 0.6 12 5.9 0.0 3.9 3 1 1 4 4 4 0 FAD-NAD(P)-binding Thi4 PF01946.17 KXH50930.1 - 0.11 11.7 0.1 15 4.8 0.0 2.4 2 0 0 2 2 2 0 Thi4 family PNPase_C PF12111.8 KXH50930.1 - 0.16 11.4 0.1 0.38 10.2 0.1 1.6 1 0 0 1 1 1 0 Polyribonucleotide phosphorylase C terminal GIDA PF01134.22 KXH50930.1 - 0.16 11.0 5.9 1.6 7.7 0.0 3.5 4 0 0 4 4 4 0 Glucose inhibited division protein A FAM75 PF14650.6 KXH50931.1 - 0.19 11.3 3.0 0.23 11.0 3.0 1.1 1 0 0 1 1 1 0 FAM75 family Esterase_phd PF10503.9 KXH50932.1 - 6.5e-21 74.8 0.5 8.3e-21 74.5 0.5 1.1 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 KXH50932.1 - 2e-07 30.7 0.1 4e-07 29.7 0.1 1.5 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 KXH50932.1 - 0.00049 20.0 0.0 0.037 13.8 0.0 2.4 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase COesterase PF00135.28 KXH50932.1 - 0.0027 16.6 0.0 0.0043 16.0 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXH50932.1 - 0.028 14.3 0.0 0.039 13.8 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Esterase PF00756.20 KXH50932.1 - 0.068 12.8 0.1 0.096 12.3 0.1 1.3 1 0 0 1 1 1 0 Putative esterase Fungal_trans PF04082.18 KXH50933.1 - 2e-12 46.7 0.0 5e-12 45.4 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH50933.1 - 1.6e-07 31.3 12.5 2.8e-07 30.5 12.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HalX PF08663.10 KXH50933.1 - 0.0085 16.4 0.3 0.019 15.3 0.3 1.6 1 0 0 1 1 1 1 HalX domain P63C PF10546.9 KXH50933.1 - 0.053 14.1 1.3 0.26 11.9 0.2 2.5 1 1 1 2 2 2 0 P63C domain DASH_Dad3 PF08656.10 KXH50933.1 - 0.6 10.2 2.5 6.8 6.9 0.6 2.5 2 0 0 2 2 2 0 DASH complex subunit Dad3 TRAUB PF08164.12 KXH50934.1 - 3.2e-30 104.5 3.1 1.8e-29 102.1 0.1 2.9 2 0 0 2 2 2 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.6 KXH50934.1 - 5.7e-27 95.1 2.6 5.7e-27 95.1 2.6 2.9 3 1 0 3 3 3 1 Apoptosis antagonizing transcription factor GEN1_C PF18380.1 KXH50934.1 - 0.25 12.2 0.2 0.25 12.2 0.2 5.9 3 1 2 5 5 5 0 Holliday junction resolvase Gen1 C-terminal domain GFO_IDH_MocA PF01408.22 KXH50935.1 - 8.7e-21 75.0 0.1 1.8e-20 73.9 0.1 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.24 KXH50935.1 - 0.039 14.4 0.0 0.22 11.9 0.0 2.0 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain F_bP_aldolase PF01116.20 KXH50936.1 - 7.6e-91 304.5 0.0 9.4e-91 304.2 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Chal_sti_synt_N PF00195.19 KXH50937.1 - 2e-21 76.4 0.2 2.7e-21 76.1 0.2 1.1 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain FAE1_CUT1_RppA PF08392.12 KXH50937.1 - 2.9e-05 23.5 0.0 3.4e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein ACP_syn_III PF08545.10 KXH50937.1 - 0.005 16.7 0.1 0.013 15.4 0.1 1.7 1 1 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DUF1150 PF06620.11 KXH50937.1 - 0.16 12.1 0.0 0.29 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1150) Flu_NP PF00506.18 KXH50992.1 - 0.065 11.9 0.0 0.086 11.5 0.0 1.1 1 0 0 1 1 1 0 Influenza virus nucleoprotein adh_short_C2 PF13561.6 KXH50993.1 - 3.7e-63 213.2 0.7 5.1e-63 212.8 0.7 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXH50993.1 - 1.7e-51 174.5 0.6 2.5e-51 173.9 0.6 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXH50993.1 - 5.9e-11 42.6 0.2 8.1e-11 42.1 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXH50993.1 - 8.3e-05 22.2 0.2 0.00019 21.0 0.2 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PA PF02225.22 KXH50993.1 - 0.0025 17.8 0.2 0.0078 16.2 0.1 1.9 2 0 0 2 2 2 1 PA domain GDP_Man_Dehyd PF16363.5 KXH50993.1 - 0.017 14.6 0.1 0.027 13.9 0.1 1.4 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KXH50993.1 - 0.019 14.1 0.0 0.028 13.5 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein ARID PF01388.21 KXH50994.1 - 3.7e-17 62.8 0.4 9.1e-17 61.5 0.1 1.9 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain Trns_repr_metal PF02583.17 KXH50994.1 - 0.64 10.4 2.7 0.78 10.2 0.1 2.5 3 0 0 3 3 3 0 Metal-sensitive transcriptional repressor HECT PF00632.25 KXH50997.1 - 2.4e-64 217.8 0.0 3.4e-64 217.3 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) AZUL PF16558.5 KXH50997.1 - 1.3e-21 76.6 2.6 3.2e-21 75.3 2.6 1.8 1 0 0 1 1 1 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A zf-C2H2_2 PF12756.7 KXH50998.1 - 1.1e-35 122.0 12.8 6.9e-30 103.4 4.3 3.6 3 0 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 KXH50998.1 - 7e-08 32.6 6.3 1.4e-07 31.6 3.9 4.1 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KXH50998.1 - 1.3e-06 28.6 3.2 1.3e-06 28.6 3.2 2.7 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KXH50998.1 - 0.00043 20.9 17.2 0.23 12.4 0.2 5.2 5 0 0 5 5 5 2 C2H2-type zinc finger SnoaL_2 PF12680.7 KXH50998.1 - 0.012 16.2 2.3 0.13 12.9 2.1 2.4 2 0 0 2 2 2 0 SnoaL-like domain zf-C2H2 PF00096.26 KXH50998.1 - 0.2 12.1 20.8 4.3 8.0 0.3 4.9 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 KXH50998.1 - 0.31 11.1 5.6 11 6.2 0.1 3.2 2 0 0 2 2 2 0 C2H2-type zinc finger MMR_HSR1 PF01926.23 KXH50999.1 - 2.5e-18 66.2 0.0 4.1e-18 65.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 KXH50999.1 - 4.1e-08 33.5 0.0 0.00071 19.7 0.1 2.4 2 0 0 2 2 2 2 Dynamin family FeoB_N PF02421.18 KXH50999.1 - 5e-06 26.1 0.0 0.00015 21.4 0.1 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 KXH50999.1 - 1.3e-05 24.9 0.0 3.4e-05 23.5 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IIGP PF05049.13 KXH50999.1 - 2e-05 23.8 0.0 0.05 12.6 0.0 2.1 2 0 0 2 2 2 2 Interferon-inducible GTPase (IIGP) RsgA_GTPase PF03193.16 KXH50999.1 - 0.01 15.8 0.9 0.17 11.7 0.5 2.6 2 1 0 2 2 2 1 RsgA GTPase SRPRB PF09439.10 KXH50999.1 - 0.02 14.4 0.1 0.88 9.0 0.1 2.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Septin PF00735.18 KXH50999.1 - 0.025 13.9 0.0 0.087 12.1 0.0 1.8 1 1 0 1 1 1 0 Septin AIG1 PF04548.16 KXH50999.1 - 0.049 13.0 0.1 7.5 5.8 0.0 2.2 2 0 0 2 2 2 0 AIG1 family AAA_21 PF13304.6 KXH50999.1 - 0.058 13.2 0.2 0.13 12.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system TniB PF05621.11 KXH50999.1 - 0.18 11.2 0.1 0.93 8.9 0.0 1.9 2 0 0 2 2 2 0 Bacterial TniB protein AAA_15 PF13175.6 KXH50999.1 - 0.25 11.0 0.0 0.4 10.3 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain zf-C3HC PF07967.13 KXH51000.1 - 1.1e-39 135.5 1.5 1.7e-35 122.0 0.5 2.6 3 0 0 3 3 3 2 C3HC zinc finger-like Rsm1 PF08600.10 KXH51000.1 - 1.5e-27 95.5 1.0 4e-26 91.0 0.0 2.6 2 1 0 2 2 2 1 Rsm1-like BIR PF00653.21 KXH51000.1 - 0.00019 22.0 0.1 0.0062 17.2 0.1 2.5 2 0 0 2 2 2 1 Inhibitor of Apoptosis domain SRP40_C PF05022.12 KXH51001.1 - 1.4e-22 80.3 0.2 1.4e-22 80.3 0.2 2.7 3 0 0 3 3 3 1 SRP40, C-terminal domain A_deaminase PF00962.22 KXH51002.1 - 1.6e-26 93.5 1.2 2.1e-25 89.7 0.0 2.4 2 1 0 2 2 2 1 Adenosine/AMP deaminase A_deaminase_N PF08451.11 KXH51002.1 - 5.8e-06 26.5 0.8 3.5e-05 24.0 0.4 2.5 2 1 0 2 2 2 1 Adenosine/AMP deaminase N-terminal MCR_alpha PF02249.17 KXH51002.1 - 0.085 13.3 0.1 0.18 12.3 0.1 1.5 1 0 0 1 1 1 0 Methyl-coenzyme M reductase alpha subunit, C-terminal domain DUF5363 PF17320.2 KXH51002.1 - 0.12 12.2 0.9 10 6.1 0.3 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5363) Cupin_2 PF07883.11 KXH51003.1 - 1.5e-10 40.7 0.5 2.1e-05 24.2 0.0 3.1 3 0 0 3 3 3 2 Cupin domain Cupin_1 PF00190.22 KXH51003.1 - 5.6e-06 26.0 0.4 0.0054 16.3 0.0 2.9 3 0 0 3 3 3 2 Cupin Cupin_3 PF05899.12 KXH51003.1 - 0.00035 20.2 0.0 0.049 13.3 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF861) Cupin_6 PF12852.7 KXH51003.1 - 0.0029 17.3 0.0 0.59 9.8 0.0 2.4 2 0 0 2 2 2 2 Cupin ARD PF03079.14 KXH51003.1 - 0.16 12.1 0.0 13 5.9 0.0 2.2 2 0 0 2 2 2 0 ARD/ARD' family Histone_H2A_C PF16211.5 KXH51003.1 - 0.21 11.4 1.0 0.36 10.6 0.0 2.0 2 0 0 2 2 2 0 C-terminus of histone H2A GMC_oxred_N PF00732.19 KXH51004.1 - 3.5e-46 157.9 0.0 4.5e-46 157.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXH51004.1 - 3.4e-31 108.7 0.0 5.9e-31 107.9 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 KXH51004.1 - 0.0062 16.2 1.1 0.018 14.7 1.1 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KXH51004.1 - 0.055 12.2 0.0 4.6 5.8 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_8 PF13450.6 KXH51004.1 - 0.06 13.6 0.2 0.31 11.3 0.0 2.3 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXH51004.1 - 0.077 12.2 0.1 3.8 6.7 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Arabinose_bd PF12625.7 KXH51004.1 - 0.079 13.0 0.1 0.14 12.2 0.1 1.4 1 0 0 1 1 1 0 Arabinose-binding domain of AraC transcription regulator, N-term Thi4 PF01946.17 KXH51004.1 - 0.11 11.7 0.0 0.23 10.7 0.0 1.4 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.6 KXH51004.1 - 0.12 12.4 0.0 0.33 10.9 0.0 1.8 1 0 0 1 1 1 0 FAD-NAD(P)-binding FAD_binding_1 PF00667.20 KXH51005.1 - 5.6e-60 202.7 0.0 4.7e-59 199.7 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain POR PF01558.18 KXH51005.1 - 6.3e-11 42.7 0.1 1.5e-10 41.4 0.1 1.6 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase NAD_binding_1 PF00175.21 KXH51005.1 - 1.1e-08 35.6 0.0 2.9e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain PFOR_II PF17147.4 KXH51005.1 - 2.5e-07 30.9 0.0 7.7e-07 29.4 0.0 1.9 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II Transketolase_C PF02780.20 KXH51005.1 - 0.036 13.9 0.1 0.12 12.3 0.1 1.9 1 0 0 1 1 1 0 Transketolase, C-terminal domain E1-E2_ATPase PF00122.20 KXH51006.1 - 5.7e-47 159.6 0.6 5.7e-47 159.6 0.6 2.2 2 1 0 2 2 2 1 E1-E2 ATPase HMA PF00403.26 KXH51006.1 - 7.8e-36 122.3 2.6 3.1e-12 46.7 0.2 4.8 4 0 0 4 4 4 4 Heavy-metal-associated domain Hydrolase PF00702.26 KXH51006.1 - 4.2e-34 118.7 0.8 1.7e-33 116.7 0.8 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KXH51006.1 - 2.2e-06 28.2 0.1 4.8e-06 27.1 0.1 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KXH51006.1 - 6.8e-06 26.0 0.3 0.00016 21.6 0.3 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Poly_export PF02563.16 KXH51006.1 - 0.12 12.7 0.0 5.8 7.2 0.0 2.7 2 0 0 2 2 2 0 Polysaccharide biosynthesis/export protein Pox_E10 PF04805.12 KXH51006.1 - 1.1 9.2 3.2 7.8 6.4 0.1 3.2 4 0 0 4 4 4 0 E10-like protein conserved region Pollen_Ole_e_I PF01190.17 KXH51006.1 - 1.3 9.4 6.8 23 5.4 0.1 3.6 4 0 0 4 4 4 0 Pollen proteins Ole e I like RseC_MucC PF04246.12 KXH51006.1 - 3.9 7.4 6.3 2.1 8.3 3.0 2.3 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC DUF3795 PF12675.7 KXH51006.1 - 7.6 7.0 6.7 86 3.6 1.2 3.9 4 1 1 5 5 5 0 Protein of unknown function (DUF3795) IglC PF11550.8 KXH51043.1 - 0.011 15.3 0.2 0.094 12.2 0.1 2.3 2 0 0 2 2 2 0 Intracellular growth locus C protein DUF3498 PF12004.8 KXH51043.1 - 0.21 10.7 6.4 0.29 10.3 6.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3498) R2K_3 PF14243.6 KXH51044.1 - 0.043 13.8 0.1 0.082 12.9 0.1 1.4 1 0 0 1 1 1 0 ATP-grasp domain, R2K clade family 3 Choline_transpo PF04515.12 KXH51046.1 - 1.7e-82 277.3 25.5 1.7e-82 277.3 25.5 2.3 2 1 0 2 2 2 1 Plasma-membrane choline transporter Pex14_N PF04695.13 KXH51046.1 - 0.027 15.1 4.2 0.076 13.7 4.2 1.7 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PQQ PF01011.21 KXH51047.1 - 0.059 13.3 0.2 0.38 10.8 0.2 2.4 1 0 0 1 1 1 0 PQQ enzyme repeat PQQ_3 PF13570.6 KXH51047.1 - 0.072 13.6 6.8 3 8.5 0.0 5.5 6 1 0 6 6 6 0 PQQ-like domain APG17 PF04108.12 KXH51048.1 - 9.2e-138 459.6 1.3 1.1e-137 459.4 1.3 1.0 1 0 0 1 1 1 1 Autophagy protein Apg17 SF-assemblin PF06705.11 KXH51048.1 - 0.0015 17.9 3.6 0.0025 17.2 0.2 2.8 4 0 0 4 4 4 1 SF-assemblin/beta giardin DUF1664 PF07889.12 KXH51048.1 - 0.2 11.7 8.9 0.37 10.9 0.4 3.5 4 1 0 4 4 4 0 Protein of unknown function (DUF1664) LXG PF04740.12 KXH51048.1 - 0.31 10.7 7.4 0.21 11.3 2.3 2.8 2 2 0 2 2 2 0 LXG domain of WXG superfamily TPR_MLP1_2 PF07926.12 KXH51048.1 - 0.62 10.1 5.7 4.1 7.5 3.4 2.6 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein CLZ PF16526.5 KXH51048.1 - 3.3 8.1 7.3 4 7.9 0.2 3.5 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels AHD PF17793.1 KXH51048.1 - 5.3 6.9 5.4 0.91 9.4 0.3 2.4 3 0 0 3 3 3 0 ANC1 homology domain (AHD) DUF948 PF06103.11 KXH51048.1 - 5.6 7.3 9.2 8.3 6.7 0.3 3.5 4 1 0 4 4 4 0 Bacterial protein of unknown function (DUF948) HTH_12 PF08461.10 KXH51049.1 - 0.028 14.3 0.0 0.049 13.6 0.0 1.4 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain Antimicrobial11 PF08106.11 KXH51049.1 - 0.62 10.2 3.2 1.7 8.8 3.2 1.8 1 0 0 1 1 1 0 Formaecin family Glyco_hydro_3_C PF01915.22 KXH51050.1 - 1.4e-47 162.3 0.0 2.8e-47 161.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KXH51050.1 - 2.7e-35 122.3 0.0 3.8e-35 121.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KXH51050.1 - 6e-26 90.4 0.4 1.1e-25 89.5 0.4 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain GMC_oxred_N PF00732.19 KXH51051.1 - 4.1e-32 111.8 0.0 2.9e-22 79.4 0.0 3.2 3 0 0 3 3 3 3 GMC oxidoreductase GMC_oxred_C PF05199.13 KXH51051.1 - 5.3e-28 98.3 0.1 8.7e-28 97.6 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KXH51051.1 - 0.00011 22.4 0.8 0.0004 20.5 0.8 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KXH51051.1 - 0.00015 21.0 0.1 0.0022 17.1 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 KXH51051.1 - 0.028 13.5 0.0 0.062 12.3 0.0 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KXH51051.1 - 0.031 13.5 0.0 0.11 11.7 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXH51051.1 - 0.061 12.6 0.5 1.1 8.5 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 KXH51051.1 - 0.1 12.2 0.3 0.19 11.4 0.3 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA GFO_IDH_MocA PF01408.22 KXH51053.1 - 4.3e-22 79.2 0.2 7.3e-22 78.4 0.2 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KXH51053.1 - 1.6e-06 28.1 0.0 3.3e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Fungal_trans_2 PF11951.8 KXH51054.1 - 1.7e-07 30.4 0.2 3.5e-06 26.1 0.0 2.0 2 0 0 2 2 2 2 Fungal specific transcription factor domain MFS_1 PF07690.16 KXH51055.1 - 1.9e-30 106.0 15.3 1.9e-30 106.0 15.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KXH51055.1 - 5.5e-05 22.2 2.1 5.5e-05 22.2 2.1 2.7 3 0 0 3 3 3 1 MFS_1 like family UPF0154 PF03672.13 KXH51055.1 - 0.0077 16.2 0.4 0.42 10.7 0.0 3.5 4 0 0 4 4 4 1 Uncharacterised protein family (UPF0154) TauD PF02668.16 KXH51056.1 - 3.3e-52 177.9 0.5 5e-52 177.3 0.5 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family XylR_N PF06505.11 KXH51057.1 - 0.19 11.5 0.0 1.7 8.4 0.0 2.2 1 1 0 2 2 2 0 Activator of aromatic catabolism NACHT PF05729.12 KXH51058.1 - 1e-09 38.5 0.1 2.8e-09 37.1 0.1 1.8 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KXH51058.1 - 2.5e-05 24.7 0.1 9.4e-05 22.9 0.1 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KXH51058.1 - 6e-05 23.3 0.6 0.0019 18.4 0.0 3.1 2 1 1 3 3 3 1 AAA domain ATPase_2 PF01637.18 KXH51058.1 - 0.0016 18.4 0.0 0.0032 17.4 0.0 1.5 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea NB-ARC PF00931.22 KXH51058.1 - 0.0029 16.8 0.0 0.011 15.0 0.0 1.9 2 0 0 2 2 2 1 NB-ARC domain Rad17 PF03215.15 KXH51058.1 - 0.0069 16.3 0.0 0.017 15.1 0.0 1.6 1 0 0 1 1 1 1 Rad17 P-loop domain RNA_helicase PF00910.22 KXH51058.1 - 0.0078 16.6 0.0 0.038 14.4 0.0 2.1 2 0 0 2 2 2 1 RNA helicase KAP_NTPase PF07693.14 KXH51058.1 - 0.015 14.6 0.5 3.1 6.9 0.6 2.5 1 1 1 2 2 2 0 KAP family P-loop domain AAA_14 PF13173.6 KXH51058.1 - 0.018 15.1 0.0 0.074 13.1 0.0 2.2 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KXH51058.1 - 0.026 14.9 0.0 0.063 13.7 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) HEAT PF02985.22 KXH51058.1 - 0.028 14.6 0.0 0.099 12.9 0.0 1.9 1 0 0 1 1 1 0 HEAT repeat HEAT_2 PF13646.6 KXH51058.1 - 0.03 14.7 0.3 5.2 7.5 0.0 2.8 2 0 0 2 2 2 0 HEAT repeats ABC_tran PF00005.27 KXH51058.1 - 0.036 14.6 0.0 0.14 12.7 0.0 2.0 2 0 0 2 2 2 0 ABC transporter Viral_helicase1 PF01443.18 KXH51058.1 - 0.06 13.1 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase IstB_IS21 PF01695.17 KXH51058.1 - 0.067 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.6 KXH51058.1 - 0.13 12.8 0.0 0.39 11.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain Mem_trans PF03547.18 KXH51073.1 - 3.8e-23 81.5 0.7 5.4e-23 81.0 0.7 1.2 1 0 0 1 1 1 1 Membrane transport protein SpoIIM PF01944.17 KXH51073.1 - 0.012 15.6 1.9 0.012 15.6 1.9 3.0 2 2 1 3 3 3 0 Stage II sporulation protein M NOA36 PF06524.12 KXH51073.1 - 3.5 6.9 4.0 4.8 6.4 4.0 1.1 1 0 0 1 1 1 0 NOA36 protein DUF3502 PF12010.8 KXH51074.1 - 0.024 15.3 0.2 0.19 12.4 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3502) Epimerase PF01370.21 KXH51075.1 - 1.3e-17 64.1 0.0 1.8e-17 63.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXH51075.1 - 1.4e-11 44.0 0.0 1.6e-11 43.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KXH51075.1 - 7.3e-10 38.4 0.1 7.4e-09 35.1 0.1 1.9 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 KXH51075.1 - 8e-07 29.1 1.3 4.4e-06 26.7 0.5 2.1 2 0 0 2 2 2 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KXH51075.1 - 1.6e-06 27.8 0.0 2.3e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 KXH51075.1 - 0.00019 21.1 0.3 0.0012 18.4 0.4 2.0 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.25 KXH51075.1 - 0.0003 20.3 0.8 0.00042 19.8 0.2 1.6 2 0 0 2 2 2 1 short chain dehydrogenase Polysacc_synt_2 PF02719.15 KXH51075.1 - 0.0004 19.6 0.3 0.0019 17.4 0.1 1.9 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.10 KXH51075.1 - 0.0045 16.9 1.0 0.031 14.2 1.0 2.1 1 1 0 1 1 1 1 KR domain PhyH PF05721.13 KXH51076.1 - 1.1e-18 68.2 0.0 1.8e-18 67.6 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) SCP2 PF02036.17 KXH51076.1 - 7.6e-05 23.1 0.0 0.00015 22.2 0.0 1.5 1 0 0 1 1 1 1 SCP-2 sterol transfer family Sulfate_transp PF00916.20 KXH51081.1 - 1.7e-56 191.6 12.2 2.7e-56 191.0 12.2 1.2 1 0 0 1 1 1 1 Sulfate permease family cNMP_binding PF00027.29 KXH51081.1 - 1.5e-16 60.3 0.0 3.3e-16 59.1 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.21 KXH51081.1 - 2.8e-10 39.8 0.0 5e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 STAS domain HNF-1A_C PF04813.12 KXH51081.1 - 0.65 10.8 6.0 1.4 9.8 0.2 3.0 2 0 0 2 2 2 0 Hepatocyte nuclear factor 1 (HNF-1), alpha isoform C terminus FAM176 PF14851.6 KXH51081.1 - 3 7.5 4.4 13 5.4 0.0 2.6 2 0 0 2 2 2 0 FAM176 family EF1_GNE PF00736.19 KXH51082.1 - 6.7e-33 112.7 1.1 1.5e-32 111.6 1.1 1.6 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 KXH51082.1 - 6e-14 52.2 9.6 6e-14 52.2 9.6 3.0 4 0 0 4 4 4 1 Eukaryotic elongation factor 1 beta central acidic region Sld5 PF05916.11 KXH51082.1 - 5.2e-12 46.2 0.0 1.3e-11 44.9 0.0 1.7 1 0 0 1 1 1 1 GINS complex protein GST_C PF00043.25 KXH51082.1 - 0.00011 22.4 0.0 0.00043 20.4 0.0 2.1 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KXH51082.1 - 0.0006 20.0 0.4 0.0025 17.9 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KXH51082.1 - 0.067 13.2 0.3 0.58 10.2 0.3 2.4 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Proteasom_Rpn13 PF04683.13 KXH51083.1 - 4.9e-26 91.1 0.0 7.8e-26 90.5 0.0 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor RPN13_C PF16550.5 KXH51083.1 - 1.7e-10 41.0 0.5 1.2e-09 38.4 0.5 2.1 1 1 0 1 1 1 1 UCH-binding domain L27_2 PF09045.10 KXH51083.1 - 0.018 15.0 0.1 0.037 14.0 0.1 1.5 1 0 0 1 1 1 0 L27_2 RRM_1 PF00076.22 KXH51084.1 - 5.8e-13 48.5 0.0 2.8e-05 23.8 0.0 3.0 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KXH51084.1 - 0.12 12.5 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif HofP PF10748.9 KXH51085.1 - 0.18 11.3 0.1 0.47 10.0 0.0 1.6 2 0 0 2 2 2 0 DNA utilization proteins HofP DUF3405 PF11885.8 KXH51086.1 - 1e-230 766.8 5.7 1.2e-230 766.5 5.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) EMP24_GP25L PF01105.24 KXH51087.1 - 3.5e-46 157.4 0.0 4e-46 157.2 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Dioxygenase_C PF00775.21 KXH51087.1 - 0.083 12.3 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Dioxygenase NuiA PF07924.11 KXH51087.1 - 0.14 12.6 0.0 0.22 11.9 0.0 1.3 1 0 0 1 1 1 0 Nuclease A inhibitor-like protein Arf PF00025.21 KXH51088.1 - 2.6e-80 268.0 0.3 3e-80 267.8 0.3 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KXH51088.1 - 1.7e-14 54.1 0.0 2.3e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KXH51088.1 - 2e-14 53.4 0.0 2.5e-14 53.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 KXH51088.1 - 2.6e-13 49.9 1.5 2e-09 37.1 0.5 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 KXH51088.1 - 3.4e-13 49.5 0.0 3.8e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KXH51088.1 - 1.2e-10 41.1 0.0 1.6e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KXH51088.1 - 2.9e-06 27.3 0.0 4.5e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 KXH51088.1 - 0.0095 15.3 1.0 0.028 13.7 1.0 1.8 1 1 0 1 1 1 1 6-phosphofructo-2-kinase AAA_2 PF07724.14 KXH51089.1 - 4e-44 150.8 0.0 4.2e-43 147.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 KXH51089.1 - 2.6e-35 120.5 2.2 2.6e-35 120.5 2.2 2.6 1 1 1 2 2 2 1 AAA lid domain ClpB_D2-small PF10431.9 KXH51089.1 - 1.8e-24 85.6 0.1 5.7e-24 84.0 0.1 1.9 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 KXH51089.1 - 2.5e-18 66.8 0.1 1.9e-09 38.0 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KXH51089.1 - 1.2e-11 44.7 0.0 1.9e-08 34.4 0.0 3.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KXH51089.1 - 6.3e-09 36.4 4.6 0.00092 19.6 0.6 4.0 2 2 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 KXH51089.1 - 7e-07 29.6 0.7 0.063 13.6 0.1 3.4 2 2 0 2 2 2 2 AAA domain Sigma54_activat PF00158.26 KXH51089.1 - 8.1e-07 28.9 0.2 0.00068 19.4 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain TniB PF05621.11 KXH51089.1 - 2.6e-06 27.0 0.1 0.0011 18.4 0.1 3.5 3 1 0 3 3 2 1 Bacterial TniB protein NACHT PF05729.12 KXH51089.1 - 2e-05 24.5 0.0 0.091 12.7 0.0 2.6 2 0 0 2 2 2 2 NACHT domain ATPase_2 PF01637.18 KXH51089.1 - 5.6e-05 23.2 7.2 0.8 9.6 0.1 4.4 3 2 0 4 4 4 2 ATPase domain predominantly from Archaea AAA_14 PF13173.6 KXH51089.1 - 9.2e-05 22.5 0.0 0.47 10.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 KXH51089.1 - 0.00033 20.2 0.0 0.82 9.2 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region IstB_IS21 PF01695.17 KXH51089.1 - 0.00043 20.1 0.3 0.5 10.1 0.0 2.7 2 1 0 2 2 2 2 IstB-like ATP binding protein AAA_18 PF13238.6 KXH51089.1 - 0.00047 20.7 0.6 0.31 11.6 0.0 3.2 3 0 0 3 3 3 1 AAA domain ABC_tran PF00005.27 KXH51089.1 - 0.00069 20.1 1.5 0.32 11.5 0.0 3.4 3 0 0 3 3 3 1 ABC transporter AAA_23 PF13476.6 KXH51089.1 - 0.0033 18.0 8.2 1.5 9.3 4.6 3.3 3 0 0 3 3 3 1 AAA domain AAA_24 PF13479.6 KXH51089.1 - 0.0041 16.9 0.8 1.2 8.8 0.0 2.7 3 0 0 3 3 2 1 AAA domain AAA_33 PF13671.6 KXH51089.1 - 0.0056 16.8 0.0 2.4 8.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KXH51089.1 - 0.0063 16.9 0.0 1.1 9.6 0.0 3.0 2 1 0 2 2 2 1 RNA helicase RsgA_GTPase PF03193.16 KXH51089.1 - 0.0078 16.1 0.0 1.5 8.7 0.0 2.8 2 0 0 2 2 2 1 RsgA GTPase AAA_30 PF13604.6 KXH51089.1 - 0.0091 15.7 0.1 0.39 10.4 0.0 3.1 3 0 0 3 3 3 1 AAA domain PhoH PF02562.16 KXH51089.1 - 0.014 14.8 0.1 0.31 10.5 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein AAA_28 PF13521.6 KXH51089.1 - 0.018 15.3 0.7 14 5.9 0.0 3.5 3 1 0 3 3 2 0 AAA domain AAA_25 PF13481.6 KXH51089.1 - 0.021 14.4 0.2 0.33 10.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain ResIII PF04851.15 KXH51089.1 - 0.023 14.7 0.2 12 5.9 0.0 3.4 2 1 0 3 3 3 0 Type III restriction enzyme, res subunit SRP54 PF00448.22 KXH51089.1 - 0.028 14.1 0.1 0.66 9.6 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Roc PF08477.13 KXH51089.1 - 0.037 14.3 0.1 3.5 7.9 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Mg_chelatase PF01078.21 KXH51089.1 - 0.04 13.3 0.1 2.7 7.3 0.0 3.0 2 1 0 2 2 2 0 Magnesium chelatase, subunit ChlI DUF4407 PF14362.6 KXH51089.1 - 0.04 13.3 3.6 0.064 12.6 3.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) UvrD-helicase PF00580.21 KXH51089.1 - 0.04 13.4 2.5 0.25 10.8 0.1 2.2 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain PduV-EutP PF10662.9 KXH51089.1 - 0.045 13.5 0.0 0.91 9.3 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation OEP PF02321.18 KXH51089.1 - 0.062 13.1 4.3 1 9.1 5.0 2.3 2 0 0 2 2 2 0 Outer membrane efflux protein PIF1 PF05970.14 KXH51089.1 - 0.091 11.9 0.0 5.9 5.9 0.0 2.7 3 0 0 3 3 3 0 PIF1-like helicase TsaE PF02367.17 KXH51089.1 - 0.095 12.7 0.1 10 6.1 0.0 2.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zw10 PF06248.13 KXH51089.1 - 0.11 11.1 1.5 0.16 10.5 1.5 1.2 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 AAA_21 PF13304.6 KXH51089.1 - 0.15 11.8 0.3 2.5 7.8 0.0 2.9 2 1 1 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system ATP_bind_1 PF03029.17 KXH51089.1 - 0.18 11.5 0.1 2.9 7.6 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_19 PF13245.6 KXH51089.1 - 0.23 11.8 3.1 1.3 9.4 0.3 3.1 2 2 1 3 3 3 0 AAA domain UPF0242 PF06785.11 KXH51089.1 - 1.2 9.2 10.0 2.7 8.0 10.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF16 PF01519.16 KXH51089.1 - 1.7 9.2 7.3 28 5.3 5.0 3.3 3 1 0 3 3 2 0 Protein of unknown function DUF16 GrpE PF01025.19 KXH51089.1 - 2.7 7.6 8.8 3.9 7.1 7.3 2.1 2 0 0 2 2 1 0 GrpE Seryl_tRNA_N PF02403.22 KXH51089.1 - 2.9 8.2 15.3 1.8 8.8 9.1 3.2 3 1 0 3 3 1 0 Seryl-tRNA synthetase N-terminal domain ABC_tran_CTD PF16326.5 KXH51089.1 - 3.7 7.9 18.8 0.23 11.7 9.2 3.4 3 1 1 4 4 2 0 ABC transporter C-terminal domain Fungal_TACC PF12709.7 KXH51089.1 - 4.5 7.8 8.6 2.6 8.6 3.2 2.8 2 1 1 3 3 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins DUF4337 PF14235.6 KXH51089.1 - 5.7 7.0 5.4 10 6.2 5.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) PKcGMP_CC PF16808.5 KXH51089.1 - 9.1 6.2 9.8 12 5.9 1.6 3.0 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF4061 PF13270.6 KXH51089.1 - 9.4 6.6 7.4 15 5.9 0.4 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4061) Ribosomal_L6e PF01159.19 KXH51090.1 - 7.4e-40 135.9 0.3 1.3e-39 135.1 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L6e Peptidase_M49 PF03571.15 KXH51091.1 - 3.9e-249 827.6 0.0 4.6e-249 827.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M49 TetR_C_23 PF17931.1 KXH51091.1 - 0.081 13.0 0.2 0.85 9.7 0.0 2.3 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain SKI PF01202.22 KXH51092.1 - 1.9e-11 44.4 0.0 2.4e-11 44.0 0.0 1.1 1 0 0 1 1 1 1 Shikimate kinase AAA_33 PF13671.6 KXH51092.1 - 3e-09 37.2 0.0 4.6e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KXH51092.1 - 1.2e-08 35.6 0.0 4.2e-08 33.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain Rad17 PF03215.15 KXH51092.1 - 1.3e-05 25.2 0.0 2.4e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain Cytidylate_kin PF02224.18 KXH51092.1 - 1.8e-05 24.6 0.0 4.6e-05 23.3 0.0 1.6 2 0 0 2 2 2 1 Cytidylate kinase AAA_17 PF13207.6 KXH51092.1 - 3.4e-05 24.3 0.0 8.8e-05 22.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 KXH51092.1 - 7.2e-05 23.2 0.1 0.00021 21.7 0.0 1.8 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KXH51092.1 - 0.0002 21.8 0.0 0.00051 20.5 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KXH51092.1 - 0.00071 19.9 0.0 0.002 18.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 KXH51092.1 - 0.0015 18.5 0.0 0.0027 17.6 0.0 1.4 1 0 0 1 1 1 1 NACHT domain PRK PF00485.18 KXH51092.1 - 0.0018 18.1 0.0 0.0033 17.2 0.0 1.4 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family Thymidylate_kin PF02223.17 KXH51092.1 - 0.002 17.9 0.0 1 9.0 0.0 2.2 2 0 0 2 2 2 2 Thymidylate kinase dNK PF01712.19 KXH51092.1 - 0.002 18.0 0.0 0.18 11.7 0.0 2.2 2 0 0 2 2 2 1 Deoxynucleoside kinase CoaE PF01121.20 KXH51092.1 - 0.0022 17.7 0.0 0.017 14.8 0.0 2.2 2 0 0 2 2 2 1 Dephospho-CoA kinase AAA_28 PF13521.6 KXH51092.1 - 0.0026 18.0 0.0 0.01 16.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KXH51092.1 - 0.0027 18.0 0.0 0.005 17.2 0.0 1.4 1 0 0 1 1 1 1 RNA helicase AAA_5 PF07728.14 KXH51092.1 - 0.003 17.6 0.0 0.0056 16.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ATPase_2 PF01637.18 KXH51092.1 - 0.0065 16.4 0.1 0.029 14.3 0.0 1.9 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea ABC_tran PF00005.27 KXH51092.1 - 0.013 16.0 0.0 0.023 15.2 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Cytidylate_kin2 PF13189.6 KXH51092.1 - 0.014 15.5 0.1 0.078 13.1 0.0 2.0 2 0 0 2 2 2 0 Cytidylate kinase-like family AAA_30 PF13604.6 KXH51092.1 - 0.026 14.3 0.0 0.051 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KXH51092.1 - 0.027 14.5 0.0 0.043 13.8 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 KXH51092.1 - 0.029 13.8 0.0 0.065 12.6 0.0 1.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 KXH51092.1 - 0.03 14.4 0.0 0.082 12.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 KXH51092.1 - 0.03 14.2 0.0 0.044 13.7 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase T2SSE PF00437.20 KXH51092.1 - 0.04 13.0 0.0 0.067 12.2 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein NTPase_1 PF03266.15 KXH51092.1 - 0.045 13.7 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 NTPase AAA_7 PF12775.7 KXH51092.1 - 0.053 13.0 0.0 0.15 11.5 0.0 1.7 2 1 0 2 2 2 0 P-loop containing dynein motor region AAA_23 PF13476.6 KXH51092.1 - 0.058 13.9 0.0 0.094 13.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain DNA_pol3_delta2 PF13177.6 KXH51092.1 - 0.067 13.0 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase III, delta subunit RuvB_N PF05496.12 KXH51092.1 - 0.069 12.9 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_19 PF13245.6 KXH51092.1 - 0.11 12.9 0.0 0.33 11.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 KXH51092.1 - 0.13 11.7 0.1 0.21 11.0 0.1 1.3 1 0 0 1 1 1 0 PhoH-like protein ADK PF00406.22 KXH51092.1 - 0.19 11.8 0.1 2.8 8.0 0.0 2.1 2 0 0 2 2 2 0 Adenylate kinase ATPase PF06745.13 KXH51092.1 - 0.19 11.0 0.1 0.89 8.9 0.0 1.9 2 0 0 2 2 2 0 KaiC 2-oxoacid_dh PF00198.23 KXH51093.1 - 6.9e-73 244.9 0.0 2.3e-72 243.2 0.0 1.7 2 0 0 2 2 2 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KXH51093.1 - 1.1e-16 60.4 0.1 2e-16 59.6 0.1 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 KXH51093.1 - 1.1e-13 51.3 0.1 2.4e-13 50.2 0.1 1.7 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 KXH51093.1 - 0.076 12.8 0.1 0.26 11.2 0.1 1.8 2 0 0 2 2 2 0 Biotin-lipoyl like BEX PF04538.12 KXH51093.1 - 0.12 12.9 2.5 1.7 9.2 0.0 2.4 2 0 0 2 2 2 0 Brain expressed X-linked like family ATP-synt_10 PF05176.14 KXH51094.1 - 1.7e-75 253.6 0.0 2.2e-75 253.2 0.0 1.1 1 0 0 1 1 1 1 ATP10 protein V-SNARE_C PF12352.8 KXH51095.1 - 2e-12 47.2 0.8 2e-12 47.2 0.8 2.5 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus STAT_alpha PF01017.20 KXH51095.1 - 0.021 14.7 5.2 0.83 9.5 2.4 3.0 2 1 0 2 2 2 0 STAT protein, all-alpha domain Spc7 PF08317.11 KXH51095.1 - 0.18 10.7 9.6 0.37 9.6 9.8 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein Syntaxin-6_N PF09177.11 KXH51095.1 - 1.8 9.2 8.9 1.7 9.2 5.7 2.7 2 1 1 3 3 3 0 Syntaxin 6, N-terminal DUF1451 PF07295.11 KXH51095.1 - 3.5 7.6 7.7 7.1 6.7 3.0 2.2 1 1 1 2 2 2 0 Zinc-ribbon containing domain Ribosomal_L29 PF00831.23 KXH51096.1 - 3.9e-17 62.0 3.4 1e-16 60.6 0.4 2.1 2 0 0 2 2 2 2 Ribosomal L29 protein zf-H2C2_2 PF13465.6 KXH51097.1 - 6.6e-21 73.7 44.5 3.2e-08 33.7 0.1 6.9 7 0 0 7 7 7 4 Zinc-finger double domain zf-C2H2 PF00096.26 KXH51097.1 - 1.8e-14 53.3 47.1 0.00023 21.5 0.8 7.7 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXH51097.1 - 2e-10 40.6 45.6 0.0044 17.7 0.4 8.1 8 0 0 8 8 8 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KXH51097.1 - 0.002 18.4 20.3 0.29 11.5 0.2 5.6 5 0 0 5 5 5 2 Zinc-finger double-stranded RNA-binding BolA PF01722.18 KXH51097.1 - 0.048 13.9 3.7 1.2 9.5 0.1 3.3 2 1 1 3 3 3 0 BolA-like protein zf-met PF12874.7 KXH51097.1 - 0.11 12.9 18.7 0.46 11.0 0.2 6.2 6 0 0 6 6 6 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KXH51097.1 - 0.16 12.0 0.1 0.16 12.0 0.1 5.5 6 0 0 6 6 6 0 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KXH51097.1 - 0.75 9.6 28.5 0.15 11.9 0.9 5.7 5 0 0 5 5 5 0 C2H2-type zinc-finger domain AICARFT_IMPCHas PF01808.18 KXH51098.1 - 1.3e-90 303.9 0.0 1.7e-90 303.5 0.0 1.1 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 KXH51098.1 - 1.8e-23 82.6 0.0 3.2e-23 81.7 0.0 1.5 1 0 0 1 1 1 1 MGS-like domain Lactamase_B_2 PF12706.7 KXH51098.1 - 0.046 13.2 0.0 12 5.4 0.0 2.6 2 1 0 2 2 2 0 Beta-lactamase superfamily domain PRP1_N PF06424.12 KXH51099.1 - 0.1 13.0 6.1 0.12 12.8 6.1 1.1 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal DEAD PF00270.29 KXH51100.1 - 1.1e-50 171.8 0.0 1.3e-48 165.0 0.0 2.2 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 KXH51100.1 - 7.2e-26 90.7 0.0 2.2e-25 89.1 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain EVI2A PF05399.11 KXH51100.1 - 0.29 10.7 2.4 0.73 9.4 2.4 1.7 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) HCNGP PF07818.13 KXH51101.1 - 5.3e-26 91.1 0.0 8.9e-26 90.4 0.0 1.3 1 0 0 1 1 1 1 HCNGP-like protein CCDC53 PF10152.9 KXH51101.1 - 4.3 7.8 6.4 7.2 7.0 6.4 1.4 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex DUF3712 PF12505.8 KXH51102.1 - 1e-26 93.6 3.8 2e-26 92.7 3.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3712) SBF_like PF13593.6 KXH51102.1 - 0.083 12.2 0.1 0.12 11.7 0.1 1.1 1 0 0 1 1 1 0 SBF-like CPA transporter family (DUF4137) DUF2997 PF11211.8 KXH51102.1 - 0.17 11.7 0.5 0.47 10.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2997) FMN_dh PF01070.18 KXH51103.1 - 2.4e-109 365.6 0.0 3e-109 365.3 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 KXH51103.1 - 3.5e-19 68.7 0.0 9.3e-19 67.4 0.0 1.8 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 KXH51103.1 - 1.4e-07 31.0 0.1 2.2e-07 30.3 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 KXH51103.1 - 6.5e-06 25.4 0.3 3e-05 23.2 0.1 2.1 2 1 1 3 3 3 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.21 KXH51103.1 - 0.0098 15.4 0.0 0.017 14.6 0.0 1.2 1 0 0 1 1 1 1 Histidine biosynthesis protein NMO PF03060.15 KXH51103.1 - 0.016 14.6 0.2 0.025 14.0 0.2 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase Ribul_P_3_epim PF00834.19 KXH51103.1 - 0.042 13.2 0.0 0.063 12.6 0.0 1.3 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family HSCB_C PF07743.13 KXH51104.1 - 1.3e-19 70.4 5.2 1.4e-18 67.1 3.7 2.2 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 KXH51104.1 - 2.7e-07 30.6 0.3 6.1e-07 29.5 0.3 1.5 1 0 0 1 1 1 1 DnaJ domain PCI PF01399.27 KXH51105.1 - 1.8e-10 41.3 0.0 4.7e-10 39.9 0.0 1.7 1 0 0 1 1 1 1 PCI domain RPN7 PF10602.9 KXH51105.1 - 0.011 15.5 0.1 0.021 14.5 0.1 1.5 1 0 0 1 1 1 0 26S proteasome subunit RPN7 Lipase_GDSL_2 PF13472.6 KXH51106.1 - 2.2e-22 80.3 0.2 2.9e-22 79.9 0.2 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KXH51106.1 - 2.8e-10 40.5 0.0 6.1e-10 39.4 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase LRR_4 PF12799.7 KXH51107.1 - 0.011 16.2 1.3 9.3 6.8 0.3 3.2 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KXH51107.1 - 0.015 15.2 0.2 0.054 13.4 0.2 2.1 1 0 0 1 1 1 0 F-box-like LRR_8 PF13855.6 KXH51107.1 - 0.1 12.4 5.0 1.5 8.6 1.6 3.2 3 1 0 3 3 3 0 Leucine rich repeat SNF2_N PF00176.23 KXH51110.1 - 6.3e-36 123.8 0.1 1.6e-33 115.9 0.0 2.1 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 KXH51110.1 - 5.3e-08 33.2 0.1 1.8e-07 31.5 0.1 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXH51110.1 - 0.00076 19.5 0.0 0.3 11.1 0.0 2.8 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit Pilosulin PF17499.2 KXH51111.1 - 0.3 11.3 2.9 0.46 10.7 1.4 2.0 1 1 1 2 2 2 0 Ant venom peptides Glyco_hydro_16 PF00722.21 KXH51112.1 - 1.8e-08 34.1 0.0 5e-08 32.6 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 Glyco_transf_34 PF05637.12 KXH51113.1 - 2.3e-64 217.4 1.3 3e-64 217.0 1.3 1.1 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Peptidase_M22 PF00814.25 KXH51115.1 - 2.9e-45 155.1 0.1 1.3e-16 61.1 0.2 4.0 4 0 0 4 4 4 4 Glycoprotease family Proteasome PF00227.26 KXH51116.1 - 1.9e-46 157.9 0.1 2.3e-46 157.7 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Cyclin_N PF00134.23 KXH51117.1 - 1.2e-09 38.0 0.1 2.7e-09 36.9 0.1 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain TFIIB PF00382.19 KXH51117.1 - 0.17 11.9 0.1 0.33 11.0 0.1 1.4 1 0 0 1 1 1 0 Transcription factor TFIIB repeat Dus PF01207.17 KXH51118.1 - 3e-33 115.2 0.0 1.2e-29 103.4 0.0 2.3 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) AIRC PF00731.20 KXH51119.1 - 3e-61 205.3 1.4 6.3e-61 204.3 0.8 1.9 2 0 0 2 2 2 1 AIR carboxylase ATP-grasp PF02222.22 KXH51119.1 - 5.6e-50 169.3 0.0 1.1e-49 168.3 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain PurK_C PF17769.1 KXH51119.1 - 5.9e-15 54.7 0.0 1.3e-14 53.6 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain Dala_Dala_lig_C PF07478.13 KXH51119.1 - 4e-06 26.5 0.0 1e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus PrpR_N PF06506.11 KXH51119.1 - 0.0019 17.8 0.0 0.036 13.6 0.0 2.5 3 0 0 3 3 3 1 Propionate catabolism activator XdhC_C PF13478.6 KXH51119.1 - 0.039 14.5 0.1 7.1 7.2 0.0 2.6 2 0 0 2 2 2 0 XdhC Rossmann domain ATP-grasp_4 PF13535.6 KXH51119.1 - 0.071 12.7 0.0 0.89 9.1 0.0 2.3 1 1 0 1 1 1 0 ATP-grasp domain FAD_binding_2 PF00890.24 KXH51121.1 - 2e-123 412.6 4.6 2.5e-123 412.3 4.6 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 KXH51121.1 - 5.9e-43 145.9 0.1 9.2e-43 145.3 0.1 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 KXH51121.1 - 3.2e-06 26.6 1.0 0.0017 17.7 0.5 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KXH51121.1 - 4.2e-05 22.8 1.4 0.017 14.2 2.1 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.17 KXH51121.1 - 6.2e-05 22.4 0.2 0.03 13.5 0.1 2.4 2 0 0 2 2 2 2 Thi4 family FAD_binding_3 PF01494.19 KXH51121.1 - 0.0015 17.9 0.8 0.0057 15.9 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 KXH51121.1 - 0.091 12.3 1.4 0.17 11.4 1.4 1.6 1 1 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 KXH51121.1 - 0.1 11.3 0.9 0.3 9.7 0.4 2.0 2 0 0 2 2 2 0 HI0933-like protein Fer2_3 PF13085.6 KXH51122.1 - 7.6e-33 112.8 0.0 1.2e-32 112.1 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 KXH51122.1 - 1.4e-08 35.2 6.1 1.4e-08 35.2 6.1 2.2 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 KXH51122.1 - 6.2e-08 32.6 3.0 6.2e-08 32.6 3.0 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 KXH51122.1 - 1.1e-07 32.2 7.0 1.1e-07 32.2 7.0 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 KXH51122.1 - 0.0011 19.5 4.1 0.0011 19.5 4.1 2.4 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.27 KXH51122.1 - 0.0012 18.8 2.1 0.0027 17.6 0.2 2.2 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_9 PF13187.6 KXH51122.1 - 0.44 10.7 13.0 1.3 9.2 10.0 2.8 2 1 2 4 4 4 0 4Fe-4S dicluster domain SpoIIE PF07228.12 KXH51123.1 - 3.5e-09 36.9 0.3 1.6e-08 34.7 0.2 2.0 1 1 1 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 KXH51123.1 - 1.1e-06 28.4 1.7 0.013 15.1 0.1 2.8 3 0 0 3 3 3 2 Protein phosphatase 2C PP2C_2 PF13672.6 KXH51123.1 - 4.2e-06 26.6 0.8 1e-05 25.3 0.8 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C GPI-anchored PF10342.9 KXH51124.1 - 7.1e-17 62.0 3.8 7.1e-17 62.0 3.8 2.8 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family RIFIN PF02009.16 KXH51124.1 - 0.61 9.9 4.0 0.65 9.8 4.0 1.1 1 0 0 1 1 1 0 Rifin Macoilin PF09726.9 KXH51124.1 - 1.8 7.0 12.3 1.9 6.9 12.3 1.1 1 0 0 1 1 1 0 Macoilin family Methyltransf_16 PF10294.9 KXH51126.1 - 0.015 15.0 0.0 0.028 14.2 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase DUF2292 PF10055.9 KXH51126.1 - 0.14 11.8 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized small protein (DUF2292) NAD_binding_8 PF13450.6 KXH51127.1 - 1.1e-08 35.1 0.0 3.2e-08 33.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KXH51127.1 - 0.00046 19.4 0.0 0.21 10.7 0.0 3.3 3 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KXH51127.1 - 0.0012 18.9 0.1 0.11 12.5 0.0 2.9 3 0 0 3 3 3 1 FAD-NAD(P)-binding FMO-like PF00743.19 KXH51127.1 - 0.0016 16.9 0.2 0.021 13.2 0.0 2.3 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KXH51127.1 - 0.0023 17.2 0.0 1.6 7.9 0.0 3.7 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXH51127.1 - 0.13 11.4 0.0 1 8.5 0.0 2.3 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase TPR_12 PF13424.6 KXH51128.1 - 1.2e-20 73.5 17.3 3.2e-08 33.8 0.3 5.1 3 1 3 6 6 6 5 Tetratricopeptide repeat TPR_10 PF13374.6 KXH51128.1 - 3.5e-13 49.0 14.5 0.00019 21.2 0.4 6.4 6 0 0 6 6 6 3 Tetratricopeptide repeat Patatin PF01734.22 KXH51128.1 - 3.8e-13 50.1 0.0 8.1e-13 49.0 0.0 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase NB-ARC PF00931.22 KXH51128.1 - 3.5e-11 42.8 0.0 7.2e-11 41.8 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 KXH51128.1 - 3e-05 24.5 0.0 0.00021 21.7 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain PPR PF01535.20 KXH51128.1 - 0.0078 16.4 0.8 7.1 7.1 0.1 4.1 4 0 0 4 4 4 1 PPR repeat TPR_MalT PF17874.1 KXH51128.1 - 0.011 15.1 9.5 0.0063 15.9 4.0 2.3 2 0 0 2 2 2 0 MalT-like TPR region TniB PF05621.11 KXH51128.1 - 0.031 13.7 0.0 0.065 12.6 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein TPR_2 PF07719.17 KXH51128.1 - 0.034 14.2 7.7 7.9 6.9 0.1 5.3 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 KXH51128.1 - 0.045 14.3 0.4 36 5.0 0.0 3.8 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KXH51128.1 - 0.063 14.1 12.0 66 4.7 0.0 6.3 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_4 PF07721.14 KXH51128.1 - 0.21 12.3 17.6 4.2 8.3 0.1 6.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.6 KXH51128.1 - 0.75 10.2 5.5 4.8 7.7 0.0 3.9 4 0 0 4 4 3 0 Tetratricopeptide repeat Fungal_trans PF04082.18 KXH51131.1 - 8.2e-11 41.4 0.0 1.4e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH51131.1 - 1.2e-05 25.3 7.2 2.3e-05 24.4 7.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Siva PF05458.12 KXH51131.1 - 0.067 12.9 1.5 0.13 12.0 1.5 1.4 1 0 0 1 1 1 0 Cd27 binding protein (Siva) Zn_clus PF00172.18 KXH51132.1 - 0.11 12.7 14.5 0.2 11.8 14.5 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_60s PF00428.19 KXH51132.1 - 0.71 10.5 4.9 9.5 6.9 1.8 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein AA_permease_2 PF13520.6 KXH51133.1 - 8.2e-72 242.4 43.2 1e-71 242.0 43.2 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXH51133.1 - 7.9e-14 51.1 42.6 2.5e-13 49.5 42.6 1.7 1 1 0 1 1 1 1 Amino acid permease Tyrosinase PF00264.20 KXH51135.1 - 1.3e-54 185.8 0.0 1.9e-54 185.3 0.0 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase Transferase PF02458.15 KXH51136.1 - 4.7e-38 131.0 0.0 1e-17 64.0 0.0 3.0 3 0 0 3 3 3 3 Transferase family DUF1195 PF06708.11 KXH51136.1 - 0.011 15.5 0.0 0.025 14.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1195) Apo-VLDL-II PF05418.11 KXH51136.1 - 0.16 12.6 0.0 0.55 10.8 0.0 1.9 2 0 0 2 2 2 0 Apovitellenin I (Apo-VLDL-II) FAD_binding_3 PF01494.19 KXH51137.1 - 2.7e-06 26.9 1.6 0.03 13.6 0.2 3.3 3 0 0 3 3 3 2 FAD binding domain DAO PF01266.24 KXH51137.1 - 0.00037 20.2 0.3 0.0016 18.1 0.2 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXH51137.1 - 0.00076 19.7 0.0 0.0023 18.1 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXH51137.1 - 0.0024 17.2 0.0 0.0039 16.5 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXH51137.1 - 0.0035 17.3 0.0 0.0087 16.1 0.0 1.7 1 0 0 1 1 1 1 FAD-NAD(P)-binding DUF1013 PF06242.11 KXH51137.1 - 0.009 16.0 0.2 0.023 14.7 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1013) FAD_oxidored PF12831.7 KXH51137.1 - 0.016 14.5 1.6 0.91 8.8 0.4 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KXH51137.1 - 0.027 13.7 0.0 0.046 13.0 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KXH51137.1 - 0.038 13.3 0.0 0.069 12.4 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 KXH51137.1 - 0.041 12.6 0.4 0.072 11.8 0.4 1.3 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_2 PF00890.24 KXH51137.1 - 0.073 12.1 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 KXH51137.1 - 0.12 12.9 0.2 0.38 11.3 0.2 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXH51137.1 - 0.18 11.0 0.0 0.37 10.0 0.0 1.4 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.22 KXH51137.1 - 0.21 10.6 0.1 0.33 10.0 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Acetyltransf_1 PF00583.25 KXH51139.1 - 4.3e-12 46.3 0.0 5.3e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXH51139.1 - 2e-09 37.4 0.0 3.1e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KXH51139.1 - 2.2e-05 25.1 0.0 2.8e-05 24.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXH51139.1 - 0.00064 20.1 0.0 0.00098 19.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXH51139.1 - 0.003 17.5 0.0 0.0061 16.5 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 KXH51139.1 - 0.0039 17.3 0.0 0.0096 16.0 0.0 1.7 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.7 KXH51139.1 - 0.074 13.2 0.0 0.12 12.6 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain AstA PF04958.12 KXH51139.1 - 0.084 11.4 0.0 0.23 10.0 0.0 1.6 1 1 1 2 2 2 0 Arginine N-succinyltransferase beta subunit MFS_1 PF07690.16 KXH51140.1 - 1.4e-43 149.2 56.2 1e-42 146.4 38.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH51140.1 - 1.1e-11 44.2 8.9 1.1e-11 44.2 8.9 3.0 3 0 0 3 3 3 1 Sugar (and other) transporter Amidase PF01425.21 KXH51141.1 - 5e-91 305.9 0.0 6.4e-91 305.6 0.0 1.1 1 0 0 1 1 1 1 Amidase Polysacc_deac_1 PF01522.21 KXH51142.1 - 2.7e-10 40.2 0.0 4.8e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF3146 PF11344.8 KXH51142.1 - 0.089 12.5 0.1 1 9.1 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3146) Fungal_trans PF04082.18 KXH51143.1 - 0.0068 15.5 0.0 0.014 14.4 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain SlyX PF04102.12 KXH51143.1 - 0.12 13.0 0.3 13 6.5 0.1 2.6 2 0 0 2 2 2 0 SlyX Transp_cyt_pur PF02133.15 KXH51144.1 - 2.8e-90 303.2 41.5 3.4e-90 302.9 41.5 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin MFS_1 PF07690.16 KXH51145.1 - 4.3e-53 180.5 35.0 3.3e-50 171.0 38.9 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KXH51145.1 - 1e-10 40.7 18.5 1.4e-10 40.3 18.5 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KXH51145.1 - 2.4e-10 39.9 8.7 2.4e-10 39.9 8.7 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 KXH51145.1 - 0.012 14.0 14.8 0.011 14.1 2.7 3.0 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Sec61_beta PF03911.16 KXH51145.1 - 0.17 11.9 0.2 0.17 11.9 0.2 2.8 2 0 0 2 2 2 0 Sec61beta family MR_MLE_C PF13378.6 KXH51146.1 - 2.6e-54 184.1 0.1 3.4e-54 183.7 0.1 1.1 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 KXH51146.1 - 7.4e-20 71.3 0.0 1.4e-19 70.4 0.0 1.4 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain adh_short PF00106.25 KXH51147.1 - 1.2e-50 171.8 0.6 1.4e-50 171.5 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXH51147.1 - 2.8e-42 144.9 0.2 4.2e-42 144.3 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH51147.1 - 2.6e-13 50.3 1.8 6.2e-13 49.0 1.8 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KXH51147.1 - 3e-05 23.6 0.1 4.6e-05 23.0 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Glyco_transf_5 PF08323.11 KXH51147.1 - 0.0089 15.7 0.0 0.061 13.0 0.0 2.1 3 0 0 3 3 3 1 Starch synthase catalytic domain GDP_Man_Dehyd PF16363.5 KXH51147.1 - 0.053 12.9 0.1 0.078 12.4 0.1 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Glyco_trans_4_4 PF13579.6 KXH51147.1 - 0.054 13.9 0.8 2.1 8.7 0.1 3.0 3 1 0 3 3 3 0 Glycosyl transferase 4-like domain THF_DHG_CYH_C PF02882.19 KXH51147.1 - 0.06 12.7 0.0 0.2 11.0 0.1 1.8 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain VirionAssem_T7 PF11653.8 KXH51147.1 - 0.11 13.0 0.6 0.27 11.8 0.3 1.8 2 0 0 2 2 2 0 Bacteriophage T7 virion assembly protein Acetyltransf_1 PF00583.25 KXH51148.1 - 2.7e-06 27.6 0.1 5.2e-06 26.7 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXH51148.1 - 6.9e-06 26.0 0.0 1.2e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXH51148.1 - 2.1e-05 24.9 0.0 4.5e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXH51148.1 - 0.0031 17.5 0.0 0.0057 16.6 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 KXH51148.1 - 0.017 15.2 0.0 0.036 14.2 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase DHDPS PF00701.22 KXH51149.1 - 1.9e-40 138.4 0.0 2.5e-40 138.0 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family ApbA PF02558.16 KXH51150.1 - 3.2e-31 108.0 0.1 4.9e-31 107.4 0.1 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 KXH51150.1 - 2e-29 102.3 0.0 3.4e-29 101.6 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal DUF3716 PF12511.8 KXH51150.1 - 9.3e-08 32.0 0.6 2e-07 30.9 0.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) MFS_1 PF07690.16 KXH51151.1 - 2.2e-37 128.8 31.6 2.2e-37 128.8 31.6 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH51151.1 - 7e-06 25.2 21.6 2.9e-05 23.1 21.4 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter SGL PF08450.12 KXH51152.1 - 3.7e-11 43.1 0.1 5.6e-11 42.5 0.1 1.3 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region MFS_1 PF07690.16 KXH51153.1 - 8.7e-46 156.4 28.6 8.7e-46 156.4 28.6 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH51153.1 - 1.5e-14 53.7 14.9 1.5e-14 53.7 14.9 2.2 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 KXH51153.1 - 1e-05 25.0 3.7 1e-05 25.0 3.7 2.9 3 0 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB OATP PF03137.20 KXH51153.1 - 0.28 9.4 15.1 0.0054 15.1 6.9 2.3 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family DUF5353 PF17304.2 KXH51153.1 - 0.37 10.6 2.7 5 7.0 0.9 2.9 2 0 0 2 2 2 0 Family of unknown function (DUF5353) MFS_3 PF05977.13 KXH51153.1 - 0.94 7.8 7.8 0.075 11.4 2.7 1.6 2 0 0 2 2 2 0 Transmembrane secretion effector VCBS PF13517.6 KXH51154.1 - 2.1e-18 66.6 16.9 1.8e-08 34.8 0.2 7.3 4 2 3 7 7 7 5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Lipase_GDSL_2 PF13472.6 KXH51154.1 - 1.3e-17 64.7 0.1 2.9e-17 63.6 0.1 1.6 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KXH51154.1 - 5.1e-11 42.9 0.0 9.9e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase TcdB_toxin_midN PF12256.8 KXH51154.1 - 5e-05 22.7 6.5 2.8 7.3 0.1 6.3 5 1 2 7 7 7 1 Insecticide toxin TcdB middle/N-terminal region PliI PF16743.5 KXH51154.1 - 0.0052 16.5 0.3 22 4.8 0.0 4.2 3 1 1 4 4 4 0 Periplasmic lysozyme inhibitor of I-type lysozyme EF-hand_1 PF00036.32 KXH51154.1 - 0.006 16.0 1.6 2.5 7.9 0.1 3.4 2 0 0 2 2 2 2 EF hand Lipase_GDSL_3 PF14606.6 KXH51154.1 - 0.033 14.3 0.0 0.072 13.2 0.0 1.5 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family Dockerin_1 PF00404.18 KXH51154.1 - 0.22 11.7 4.7 5.8 7.2 0.1 4.3 4 0 0 4 4 4 0 Dockerin type I domain FG-GAP PF01839.23 KXH51154.1 - 0.39 10.9 12.3 3.5 7.9 0.3 4.3 3 0 0 3 3 3 0 FG-GAP repeat EF-hand_5 PF13202.6 KXH51154.1 - 7.5 6.2 7.9 3.8 7.2 0.2 3.2 3 0 0 3 3 3 0 EF hand Utp14 PF04615.13 KXH51155.1 - 0.014 14.0 7.8 0.015 13.9 7.8 1.1 1 0 0 1 1 1 0 Utp14 protein PNP_UDP_1 PF01048.20 KXH51156.1 - 2.3e-05 23.7 0.0 3.6e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Phosphorylase superfamily SAS4 PF15460.6 KXH51156.1 - 0.037 14.1 2.3 1.2 9.3 0.1 2.7 3 0 0 3 3 3 0 Something about silencing, SAS, complex subunit 4 CFEM PF05730.11 KXH51157.1 - 1.1e-09 38.2 8.9 2.2e-09 37.2 8.9 1.5 1 0 0 1 1 1 1 CFEM domain adh_short PF00106.25 KXH51158.1 - 3.7e-19 69.0 0.0 7.9e-15 54.8 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXH51158.1 - 3.4e-14 53.0 0.1 4.3e-13 49.4 0.1 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 KXH51158.1 - 5.1e-06 26.5 0.0 6.8e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KXH51158.1 - 1.1e-05 25.0 0.0 1.4e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KXH51158.1 - 2.3e-05 24.4 0.3 3.8e-05 23.7 0.3 1.3 1 0 0 1 1 1 1 KR domain NmrA PF05368.13 KXH51158.1 - 0.0024 17.5 0.3 0.0036 16.9 0.3 1.3 1 0 0 1 1 1 1 NmrA-like family Glyco_transf_4 PF13439.6 KXH51158.1 - 0.024 14.6 0.0 0.037 14.0 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase Family 4 Sugar_tr PF00083.24 KXH51159.1 - 3.5e-44 151.4 16.7 4.5e-44 151.0 16.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH51159.1 - 5.3e-32 111.1 27.8 7.5e-26 90.9 11.5 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily Peptidase_S8 PF00082.22 KXH51160.1 - 1.6e-45 155.6 1.5 3.2e-45 154.7 1.5 1.5 1 0 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 KXH51160.1 - 7.5e-05 23.4 0.1 0.00036 21.2 0.0 2.2 2 1 0 2 2 2 1 Fn3-like domain PA PF02225.22 KXH51160.1 - 0.0073 16.3 0.4 0.021 14.8 0.0 2.0 2 0 0 2 2 2 1 PA domain Cupin_2 PF07883.11 KXH51161.1 - 9.3e-10 38.1 0.7 1.6e-09 37.4 0.7 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_7 PF12973.7 KXH51161.1 - 0.00011 22.1 0.1 0.00016 21.5 0.1 1.3 1 0 0 1 1 1 1 ChrR Cupin-like domain Cupin_1 PF00190.22 KXH51161.1 - 0.00019 21.0 0.1 0.00023 20.8 0.1 1.1 1 0 0 1 1 1 1 Cupin Cupin_6 PF12852.7 KXH51161.1 - 0.00042 20.1 0.3 0.00051 19.8 0.3 1.1 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.12 KXH51161.1 - 0.00071 19.2 0.2 0.00098 18.8 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF861) AraC_binding PF02311.19 KXH51161.1 - 0.00076 19.4 0.3 0.00096 19.1 0.3 1.1 1 0 0 1 1 1 1 AraC-like ligand binding domain Amidohydro_1 PF01979.20 KXH51162.1 - 6e-31 108.0 0.0 1.3e-30 106.9 0.0 1.5 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KXH51162.1 - 1.2e-14 54.6 2.4 1e-09 38.4 0.0 2.6 3 0 0 3 3 3 2 Amidohydrolase family Acetyltransf_1 PF00583.25 KXH51163.1 - 1.2e-13 51.3 0.1 2.2e-13 50.4 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 KXH51163.1 - 1.2e-11 45.4 0.0 1.8e-11 44.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXH51163.1 - 2.7e-09 37.3 0.0 4e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KXH51163.1 - 0.00013 22.1 0.0 0.0002 21.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXH51163.1 - 0.0002 21.2 0.1 0.00076 19.4 0.0 2.0 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_10 PF13673.7 KXH51163.1 - 0.00025 21.0 0.0 0.00061 19.7 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KXH51163.1 - 0.00046 19.9 0.0 0.00073 19.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Ank_2 PF12796.7 KXH51165.1 - 5.5e-26 91.0 0.0 1.6e-09 38.2 0.0 3.6 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXH51165.1 - 1.3e-19 70.3 0.2 5.9e-07 29.9 0.0 5.7 2 1 5 7 7 7 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXH51165.1 - 2.1e-19 69.3 1.2 1.3e-05 25.4 0.0 5.6 5 2 2 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXH51165.1 - 3.6e-18 63.8 0.1 0.011 16.2 0.0 7.1 7 0 0 7 7 7 4 Ankyrin repeat Ank PF00023.30 KXH51165.1 - 4.9e-18 64.7 4.2 0.00097 19.5 0.2 5.6 4 1 1 5 5 5 5 Ankyrin repeat HET PF06985.11 KXH51167.1 - 9.6e-11 42.2 4.1 3.2e-08 34.0 0.3 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Cu_bind_like PF02298.17 KXH51168.1 - 0.004 17.1 0.1 0.012 15.6 0.1 1.8 1 1 0 1 1 1 1 Plastocyanin-like domain Copper-bind PF00127.20 KXH51168.1 - 0.022 15.2 0.2 0.06 13.8 0.2 1.6 1 1 0 1 1 1 0 Copper binding proteins, plastocyanin/azurin family AF-4 PF05110.13 KXH51168.1 - 5.6 4.9 6.4 8.6 4.3 6.4 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein PKD_channel PF08016.12 KXH51169.1 - 6.1e-07 28.5 15.8 5e-05 22.2 15.9 2.5 1 1 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.31 KXH51169.1 - 5.5e-05 22.5 29.2 0.00012 21.4 22.1 2.6 2 1 0 2 2 2 1 Ion transport protein AP3D1 PF06375.11 KXH51169.1 - 0.27 11.4 7.5 0.45 10.7 7.5 1.3 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 FSH1 PF03959.13 KXH51170.1 - 3.5e-32 111.8 0.0 4.4e-32 111.5 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 KXH51170.1 - 0.0005 20.7 0.7 0.0019 18.8 0.1 1.7 1 1 1 2 2 2 1 Alpha/beta hydrolase family F-box-like PF12937.7 KXH51171.1 - 0.01 15.7 0.2 0.033 14.1 0.2 2.0 1 0 0 1 1 1 0 F-box-like FtsJ PF01728.19 KXH51172.1 - 3.2e-13 50.2 0.0 4.6e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase SSF PF00474.17 KXH51173.1 - 2.4e-17 62.9 27.9 3.7e-17 62.3 27.9 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family Bac_luciferase PF00296.20 KXH51174.1 - 5.6e-55 187.0 0.1 9.4e-55 186.2 0.1 1.2 1 0 0 1 1 1 1 Luciferase-like monooxygenase Lactamase_B PF00753.27 KXH51175.1 - 2.7e-06 27.5 3.9 5.8e-06 26.5 3.9 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily peroxidase PF00141.23 KXH51176.1 - 2.3e-29 102.7 0.0 3.8e-29 102.0 0.0 1.3 1 0 0 1 1 1 1 Peroxidase AA_permease_2 PF13520.6 KXH51177.1 - 2.7e-56 191.2 46.2 3.7e-56 190.8 46.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXH51177.1 - 5.2e-18 64.9 35.6 7.4e-18 64.4 35.6 1.2 1 0 0 1 1 1 1 Amino acid permease DUF2456 PF10445.9 KXH51177.1 - 2.8 8.1 6.8 3.7 7.7 0.1 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF2456) 60KD_IMP PF02096.20 KXH51177.1 - 6.9 6.5 10.9 0.74 9.7 4.1 2.3 2 0 0 2 2 2 0 60Kd inner membrane protein DUF1772 PF08592.11 KXH51178.1 - 4.7e-09 36.7 2.2 6.1e-09 36.3 2.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) Deltameth_res PF16020.5 KXH51178.1 - 0.54 10.2 2.6 0.5 10.3 0.3 2.0 2 0 0 2 2 2 0 Deltamethrin resistance AAA PF00004.29 KXH51179.1 - 2.5e-15 57.1 0.0 7.2e-15 55.6 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Macoilin PF09726.9 KXH51179.1 - 0.0023 16.6 16.6 0.0037 15.9 16.6 1.3 1 0 0 1 1 1 1 Macoilin family AAA_22 PF13401.6 KXH51179.1 - 0.0024 18.2 1.8 0.11 12.8 0.1 2.8 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 KXH51179.1 - 0.0038 17.2 0.0 0.0099 15.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_11 PF13086.6 KXH51179.1 - 0.011 15.6 16.9 0.14 12.0 0.0 3.5 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.6 KXH51179.1 - 0.035 13.8 0.0 0.099 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KXH51179.1 - 0.054 13.9 0.5 0.23 11.8 0.5 2.1 1 1 0 1 1 1 0 AAA ATPase domain Egh16-like PF11327.8 KXH51180.1 - 1.9e-48 165.3 8.8 2.2e-48 165.1 8.8 1.1 1 0 0 1 1 1 1 Egh16-like virulence factor HemeBinding_Shp PF11545.8 KXH51180.1 - 0.0083 16.1 0.3 0.019 15.0 0.3 1.5 1 0 0 1 1 1 1 Cell surface heme-binding protein Shp URO-D PF01208.17 KXH51196.1 - 9e-125 416.4 0.0 1e-124 416.2 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) DUF3602 PF12223.8 KXH51197.1 - 2.8e-14 53.5 5.0 7.5e-12 45.7 0.8 2.8 2 2 1 3 3 3 2 Protein of unknown function (DUF3602) AA_permease_2 PF13520.6 KXH51200.1 - 0.00049 19.1 0.1 0.00056 18.9 0.1 1.0 1 0 0 1 1 1 1 Amino acid permease TMEMspv1-c74-12 PF11044.8 KXH51200.1 - 0.04 13.9 1.1 2 8.4 0.2 2.2 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein DUF202 PF02656.15 KXH51200.1 - 0.069 13.6 0.0 0.12 12.8 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF202) Sod_Cu PF00080.20 KXH51201.1 - 2.2e-08 34.4 0.1 3.1e-08 33.9 0.1 1.3 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Fungal_trans_2 PF11951.8 KXH51205.1 - 2.6e-50 171.3 7.5 6.9e-50 170.0 7.5 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH51205.1 - 4.4e-07 29.9 7.3 1e-06 28.8 7.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RVT_1 PF00078.27 KXH51206.1 - 6.8e-06 25.7 0.0 1.5e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SUIM_assoc PF16619.5 KXH51206.1 - 0.13 12.4 0.9 0.34 11.0 0.1 2.1 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 MFS_1 PF07690.16 KXH51207.1 - 7.3e-42 143.6 45.1 7.3e-42 143.6 45.1 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH51207.1 - 2.5e-15 56.3 9.3 2.5e-15 56.3 9.3 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KXH51207.1 - 0.00062 18.3 18.9 0.00093 17.7 18.9 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) AMP-binding PF00501.28 KXH51208.1 - 3.2e-15 55.7 0.0 1.4e-14 53.6 0.0 1.8 1 1 0 1 1 1 1 AMP-binding enzyme NPCC PF08058.11 KXH51209.1 - 4.9e-29 101.0 0.0 7e-29 100.5 0.0 1.2 1 0 0 1 1 1 1 Nuclear pore complex component US30 PF17624.2 KXH51209.1 - 1.3 8.0 3.7 0.63 9.0 1.5 1.5 2 0 0 2 2 2 0 Family of unknown function Hid1 PF12722.7 KXH51210.1 - 0 1032.5 0.0 0 1032.4 0.0 1.0 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 KXH51210.1 - 5.4e-107 358.8 0.0 6.6e-107 358.5 0.0 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Ank_4 PF13637.6 KXH51210.1 - 0.0041 17.7 0.1 0.97 10.1 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) DUF913 PF06025.12 KXH51210.1 - 0.0081 15.2 0.2 0.029 13.4 0.3 1.7 2 0 0 2 2 2 1 Domain of Unknown Function (DUF913) Adeno_GP19K PF04881.13 KXH51210.1 - 0.084 12.9 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Adenovirus GP19K EHN PF06441.12 KXH51211.1 - 2.9e-21 75.9 0.5 5.9e-21 74.9 0.5 1.5 1 0 0 1 1 1 1 Epoxide hydrolase N terminus TIMELESS PF04821.14 KXH51212.1 - 9.6e-88 294.0 0.2 9.6e-88 294.0 0.2 2.7 3 0 0 3 3 3 1 Timeless protein TIMELESS_C PF05029.13 KXH51212.1 - 8.8e-33 114.3 31.6 8.8e-33 114.3 31.6 3.3 2 1 0 2 2 2 1 Timeless protein C terminal region AAA_16 PF13191.6 KXH51212.1 - 0.16 12.4 2.0 0.85 10.0 0.7 2.7 2 0 0 2 2 2 0 AAA ATPase domain Cnd1_N PF12922.7 KXH51212.1 - 2.7 7.8 5.7 14 5.5 0.1 3.1 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1, N-term 3HCDH_N PF02737.18 KXH51213.1 - 4e-52 176.7 0.9 5.6e-52 176.2 0.9 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 KXH51213.1 - 1.5e-34 118.4 0.0 3.2e-34 117.4 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Sacchrp_dh_NADP PF03435.18 KXH51213.1 - 4.1e-05 23.8 0.1 8e-05 22.9 0.1 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Pyr_redox_2 PF07992.14 KXH51213.1 - 0.0011 18.3 0.0 0.0014 17.9 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_2 PF03446.15 KXH51213.1 - 0.0013 18.9 0.1 0.0042 17.3 0.1 1.9 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase DAO PF01266.24 KXH51213.1 - 0.0032 17.1 0.0 0.0043 16.7 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.14 KXH51213.1 - 0.032 13.8 0.1 0.06 12.9 0.1 1.5 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.19 KXH51213.1 - 0.11 11.8 0.4 0.21 10.9 0.4 1.6 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 KXH51213.1 - 0.17 12.5 1.8 0.92 10.1 1.8 2.3 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Vut_1 PF02592.15 KXH51273.1 - 0.13 12.5 2.7 0.19 12.0 2.7 1.2 1 0 0 1 1 1 0 Putative vitamin uptake transporter Cnn_1N PF07989.11 KXH51274.1 - 9.2e-10 38.5 8.5 3.1e-09 36.9 8.5 1.9 1 0 0 1 1 1 1 Centrosomin N-terminal motif 1 RAP1 PF07218.11 KXH51274.1 - 0.027 12.8 0.9 0.044 12.1 0.9 1.4 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) ESP PF16590.5 KXH51274.1 - 0.17 12.2 1.1 0.39 11.0 0.7 1.8 1 1 0 1 1 1 0 Exocrine gland-secreting peptide DUF4164 PF13747.6 KXH51274.1 - 0.35 11.2 7.1 0.93 9.8 7.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) DUF812 PF05667.11 KXH51274.1 - 0.39 9.5 5.9 0.77 8.6 5.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Cep57_CLD_2 PF14197.6 KXH51274.1 - 1.1 9.4 9.7 0.43 10.7 6.2 2.2 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 APG6_N PF17675.1 KXH51274.1 - 3 8.4 8.4 8.3 6.9 8.4 1.7 1 0 0 1 1 1 0 Apg6 coiled-coil region ABC_tran_CTD PF16326.5 KXH51274.1 - 6.4 7.1 8.1 19 5.6 8.1 1.7 1 0 0 1 1 1 0 ABC transporter C-terminal domain p450 PF00067.22 KXH51275.1 - 6.3e-32 110.9 0.0 2.4e-21 76.1 0.0 2.3 2 1 0 2 2 2 2 Cytochrome P450 Abhydrolase_1 PF00561.20 KXH51278.1 - 1.6e-12 47.6 0.0 3.2e-08 33.5 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXH51278.1 - 8e-08 33.2 0.0 9.8e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXH51278.1 - 5.8e-06 25.7 0.0 7.6e-05 22.1 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 KXH51278.1 - 0.00031 19.5 0.0 0.00095 17.9 0.0 1.7 1 1 1 2 2 2 1 Ndr family Methyltransf_23 PF13489.6 KXH51279.1 - 1.4e-18 67.3 0.0 2.3e-18 66.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH51279.1 - 5.6e-08 33.4 0.0 1.2e-07 32.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH51279.1 - 3e-07 30.4 0.0 9e-07 28.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH51279.1 - 1.3e-06 29.1 0.0 6.4e-06 26.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH51279.1 - 4.6e-06 27.2 0.0 7.7e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXH51279.1 - 0.00039 20.0 0.0 0.0006 19.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.18 KXH51279.1 - 0.0017 17.7 0.0 0.0035 16.7 0.0 1.5 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_16 PF10294.9 KXH51279.1 - 0.052 13.3 0.0 0.081 12.6 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase CMAS PF02353.20 KXH51279.1 - 0.058 12.7 0.0 0.11 11.7 0.0 1.3 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase DUF3489 PF11994.8 KXH51279.1 - 0.094 12.8 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3489) PrmA PF06325.13 KXH51279.1 - 0.15 11.4 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.17 KXH51279.1 - 0.17 11.4 0.0 0.29 10.6 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase GidB PF02527.15 KXH51279.1 - 0.17 11.2 0.0 0.6 9.4 0.0 1.7 2 0 0 2 2 2 0 rRNA small subunit methyltransferase G FtsJ PF01728.19 KXH51279.1 - 0.18 11.9 0.0 0.41 10.8 0.0 1.4 1 1 0 1 1 1 0 FtsJ-like methyltransferase Amidohydro_1 PF01979.20 KXH51280.1 - 2.9e-25 89.3 0.0 6.2e-25 88.2 0.0 1.6 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KXH51280.1 - 1.3e-15 57.9 2.1 2.9e-08 33.7 0.0 2.5 3 0 0 3 3 3 2 Amidohydrolase family Urease_alpha PF00449.20 KXH51280.1 - 0.02 15.3 1.5 0.038 14.3 0.5 2.0 2 0 0 2 2 2 0 Urease alpha-subunit, N-terminal domain AAA_33 PF13671.6 KXH51280.1 - 0.043 14.0 0.0 0.094 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain CN_hydrolase PF00795.22 KXH51281.1 - 9.5e-45 153.0 0.0 1.6e-44 152.2 0.0 1.4 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Asp_Glu_race PF01177.22 KXH51281.1 - 5.3e-10 39.5 0.0 9e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase Amdase PF17645.1 KXH51281.1 - 0.012 15.2 1.1 0.032 13.8 0.7 1.6 1 1 0 1 1 1 0 Arylmalonate decarboxylase Dimerisation2 PF16864.5 KXH51281.1 - 0.018 15.0 0.1 0.12 12.4 0.0 2.1 2 0 0 2 2 2 0 Dimerisation domain CoA_binding_2 PF13380.6 KXH51281.1 - 0.15 12.5 0.1 0.79 10.2 0.0 2.2 3 0 0 3 3 3 0 CoA binding domain Fungal_trans PF04082.18 KXH51282.1 - 3e-05 23.2 1.4 4.7e-05 22.6 0.1 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH51282.1 - 0.00012 22.1 6.0 0.00028 21.0 6.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Transp_cyt_pur PF02133.15 KXH51283.1 - 2.2e-100 336.5 34.0 2.5e-100 336.3 34.0 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin S1FA PF04689.13 KXH51283.1 - 1.1 9.4 4.7 0.21 11.8 0.3 2.1 2 0 0 2 2 2 0 DNA binding protein S1FA NAD_binding_4 PF07993.12 KXH51284.1 - 2.3e-40 138.4 0.0 3.2e-40 137.9 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 KXH51284.1 - 6.2e-29 100.8 0.0 4.5e-26 91.4 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme PP-binding PF00550.25 KXH51284.1 - 3.3e-11 43.4 0.1 1.3e-10 41.4 0.0 2.2 2 0 0 2 2 2 1 Phosphopantetheine attachment site Epimerase PF01370.21 KXH51284.1 - 4.1e-08 33.0 0.0 7.6e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KXH51284.1 - 0.015 15.2 0.0 0.051 13.5 0.0 1.8 1 1 0 1 1 1 0 KR domain GDP_Man_Dehyd PF16363.5 KXH51284.1 - 0.16 11.3 0.0 0.28 10.5 0.0 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase FAD_binding_2 PF00890.24 KXH51285.1 - 2.1e-38 132.5 1.4 3.6e-38 131.7 1.4 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KXH51285.1 - 1.4e-12 47.9 1.0 1.9e-11 44.1 1.0 2.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KXH51285.1 - 4.9e-07 29.4 1.0 7.4e-07 28.9 1.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXH51285.1 - 1.4e-05 24.5 0.3 0.00012 21.5 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXH51285.1 - 6.4e-05 21.8 0.4 0.00018 20.3 0.1 1.9 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.6 KXH51285.1 - 0.0003 21.0 3.8 0.00049 20.3 1.6 2.6 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 KXH51285.1 - 0.0024 17.0 3.7 0.0024 17.0 3.7 2.1 3 0 0 3 3 3 1 Glucose inhibited division protein A Thi4 PF01946.17 KXH51285.1 - 0.008 15.4 2.0 0.017 14.3 2.0 1.5 1 0 0 1 1 1 1 Thi4 family Catalase_C PF18011.1 KXH51285.1 - 0.058 13.0 0.1 0.13 11.9 0.1 1.5 1 0 0 1 1 1 0 C-terminal domain found in long catalases AlaDh_PNT_C PF01262.21 KXH51285.1 - 0.074 12.3 0.1 0.14 11.4 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_8 PF13450.6 KXH51287.1 - 8.3e-16 58.0 0.0 1.7e-15 56.9 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KXH51287.1 - 1.9e-06 27.4 0.5 0.00011 21.6 0.1 3.0 3 1 1 4 4 4 1 Flavin containing amine oxidoreductase DAO PF01266.24 KXH51287.1 - 4.7e-06 26.4 0.1 0.00025 20.8 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KXH51287.1 - 0.033 13.4 0.0 0.4 9.9 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain FAD_binding_2 PF00890.24 KXH51287.1 - 0.043 12.9 0.0 0.072 12.2 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.6 KXH51287.1 - 0.045 13.8 0.1 0.36 10.8 0.0 2.6 3 1 0 3 3 3 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KXH51287.1 - 0.045 13.0 0.0 0.079 12.2 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Ribosomal_L2_C PF03947.18 KXH51287.1 - 0.078 13.2 0.0 15 5.8 0.0 2.5 2 0 0 2 2 2 0 Ribosomal Proteins L2, C-terminal domain Methyltransf_25 PF13649.6 KXH51288.1 - 0.00086 20.0 0.1 0.0034 18.0 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXH51288.1 - 0.02 14.3 0.0 0.033 13.5 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 KXH51288.1 - 0.032 14.9 0.0 0.11 13.1 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.6 KXH51288.1 - 0.057 13.2 0.0 0.19 11.5 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain MFS_1 PF07690.16 KXH51289.1 - 1.6e-14 53.6 16.3 2.5e-14 53.0 16.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF4131 PF13567.6 KXH51289.1 - 0.17 11.5 2.1 0.29 10.8 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) DUF1127 PF06568.11 KXH51289.1 - 0.17 11.7 0.2 0.17 11.7 0.2 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF1127) Albumin_I PF08027.11 KXH51289.1 - 0.27 10.9 1.5 0.54 9.9 1.5 1.5 1 0 0 1 1 1 0 Albumin I chain b ADH_zinc_N PF00107.26 KXH51290.1 - 1.2e-23 83.5 0.0 1.8e-23 83.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXH51290.1 - 6.5e-21 74.3 3.1 1e-20 73.7 3.1 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 KXH51290.1 - 0.0013 18.3 0.1 0.0018 17.8 0.1 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus 2-Hacid_dh_C PF02826.19 KXH51290.1 - 0.0029 17.0 0.1 0.0047 16.3 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KXH51290.1 - 0.09 12.1 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Fer4_6 PF12837.7 KXH51291.1 - 0.15 12.1 1.3 1.6 8.9 0.1 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Cytochrom_B562 PF07361.11 KXH51291.1 - 0.2 12.4 1.6 0.74 10.5 0.2 2.4 2 0 0 2 2 2 0 Cytochrome b562 Med2 PF11214.8 KXH51291.1 - 0.71 10.1 6.0 14 5.9 1.6 3.2 2 1 1 3 3 3 0 Mediator complex subunit 2 SCO1-SenC PF02630.14 KXH51292.1 - 0.1 12.5 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 SCO1/SenC INCENP_ARK-bind PF03941.15 KXH51292.1 - 4.3 7.4 9.9 0.39 10.7 1.3 2.5 2 0 0 2 2 2 0 Inner centromere protein, ARK binding region Pex14_N PF04695.13 KXH51293.1 - 0.18 12.5 0.9 0.47 11.1 0.9 1.7 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Glyco_hydro_3 PF00933.21 KXH51294.1 - 3.3e-55 187.7 0.0 5.5e-55 187.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 KXH51294.1 - 1.7e-53 181.6 0.0 6e-53 179.8 0.0 1.9 2 1 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 KXH51294.1 - 4.2e-21 74.8 0.4 1.1e-20 73.5 0.2 1.8 2 0 0 2 2 2 1 Fibronectin type III-like domain PA14 PF07691.12 KXH51294.1 - 4.4e-06 26.6 0.0 1.4e-05 24.9 0.0 1.8 2 0 0 2 2 2 1 PA14 domain DMSP_lyase PF16867.5 KXH51295.1 - 0.14 11.8 0.0 0.31 10.7 0.0 1.5 1 0 0 1 1 1 0 Dimethlysulfonioproprionate lyase Lipase_3 PF01764.25 KXH51296.1 - 1.3e-21 77.0 0.0 2.7e-21 75.9 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KXH51296.1 - 0.0023 18.6 0.2 0.0071 17.0 0.0 1.6 1 1 0 2 2 2 1 Alpha/beta hydrolase family CM2 PF03021.14 KXH51296.1 - 0.14 12.0 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 Influenza C virus M2 protein Methyltransf_25 PF13649.6 KXH51297.1 - 1.5e-08 35.2 0.0 4.1e-08 33.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH51297.1 - 1.7e-05 24.7 0.0 4.1e-05 23.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KXH51297.1 - 0.00013 21.8 0.0 0.00021 21.1 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_11 PF08241.12 KXH51297.1 - 0.00015 22.4 0.0 0.00046 20.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXH51297.1 - 0.00079 18.8 0.0 0.0011 18.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 KXH51297.1 - 0.0014 18.5 0.0 0.0022 17.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH51297.1 - 0.0018 19.0 0.0 0.0067 17.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_24 PF13578.6 KXH51297.1 - 0.015 16.3 0.0 0.034 15.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain MetW PF07021.12 KXH51297.1 - 0.028 14.0 0.0 0.41 10.2 0.0 2.3 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW Fibrillarin PF01269.17 KXH51297.1 - 0.12 11.5 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Fibrillarin But2 PF09792.9 KXH51298.1 - 0.0057 17.0 0.0 0.014 15.8 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain Arm-DNA-bind_1 PF09003.10 KXH51299.1 - 0.014 15.5 0.0 0.025 14.7 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage lambda integrase, Arm DNA-binding domain Cadherin_4 PF17803.1 KXH51300.1 - 0.00015 22.3 7.1 9.6 6.9 0.1 5.3 2 2 3 5 5 5 1 Bacterial cadherin-like domain DUF3906 PF13046.6 KXH51300.1 - 0.0017 18.4 15.7 25 5.1 0.0 7.2 2 2 7 9 9 9 2 Protein of unknown function (DUF3906) DUF1938 PF09153.10 KXH51300.1 - 0.0019 18.3 1.0 4 7.6 0.0 3.8 2 1 2 4 4 4 1 Domain of unknown function (DUF1938) DUF5050 PF16472.5 KXH51300.1 - 0.24 10.6 8.5 5 6.3 8.4 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF5050) DUF4075 PF13294.6 KXH51300.1 - 4.2 7.6 23.0 7.7 6.8 4.5 5.0 1 1 4 5 5 5 0 Domain of unknown function (DUF4075) DUF3328 PF11807.8 KXH51301.1 - 2.9e-21 76.3 5.9 1.6e-20 73.8 5.9 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) CD225 PF04505.12 KXH51301.1 - 0.19 11.9 0.7 0.36 11.0 0.7 1.4 1 0 0 1 1 1 0 Interferon-induced transmembrane protein Tyrosinase PF00264.20 KXH51302.1 - 1.4e-40 140.0 10.4 2.5e-40 139.1 10.4 1.4 1 1 0 1 1 1 1 Common central domain of tyrosinase N2227 PF07942.12 KXH51303.1 - 2.7e-56 190.7 0.0 3.7e-56 190.3 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_11 PF08241.12 KXH51303.1 - 2.1e-10 41.1 0.0 2.8e-08 34.3 0.0 2.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH51303.1 - 3.4e-09 37.3 0.1 2.7e-05 24.8 0.0 2.6 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 KXH51303.1 - 2.9e-06 27.2 0.0 4.7e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH51303.1 - 3.1e-06 27.8 0.0 6.5e-05 23.6 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH51303.1 - 5.1e-05 23.1 0.0 0.018 14.8 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain TPMT PF05724.11 KXH51303.1 - 0.0036 17.0 0.1 0.018 14.7 0.1 2.0 1 1 1 2 2 2 1 Thiopurine S-methyltransferase (TPMT) TehB PF03848.14 KXH51303.1 - 0.01 15.3 0.0 0.022 14.2 0.0 1.5 1 0 0 1 1 1 0 Tellurite resistance protein TehB Ubie_methyltran PF01209.18 KXH51303.1 - 0.035 13.4 0.0 0.099 12.0 0.0 1.7 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.15 KXH51303.1 - 0.2 11.5 0.0 0.61 9.9 0.0 1.7 2 0 0 2 2 2 0 Hypothetical methyltransferase Methyltransf_23 PF13489.6 KXH51308.1 - 3.5e-08 33.5 0.0 4.8e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH51308.1 - 0.0081 16.0 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH51308.1 - 0.096 13.4 0.0 0.21 12.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Glyco_hydro_18 PF00704.28 KXH51309.1 - 1.3e-85 287.9 4.8 1.5e-85 287.7 4.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Asp PF00026.23 KXH51310.1 - 2.1e-36 126.0 1.0 1.1e-35 123.5 1.0 2.0 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KXH51310.1 - 9.5e-08 32.5 0.9 9.5e-08 32.5 0.9 2.1 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal CcmD PF04995.14 KXH51310.1 - 0.0012 18.9 0.5 0.0022 18.0 0.5 1.5 1 0 0 1 1 1 1 Heme exporter protein D (CcmD) LapA_dom PF06305.11 KXH51310.1 - 0.0062 16.3 0.0 0.014 15.2 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide assembly protein A domain TAXi_C PF14541.6 KXH51310.1 - 0.023 14.5 0.0 0.041 13.7 0.0 1.4 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal Dmrt1 PF12374.8 KXH51310.1 - 2.7 8.5 8.2 22 5.6 0.1 3.7 3 0 0 3 3 3 0 Double-sex mab3 related transcription factor 1 FMN_red PF03358.15 KXH51311.1 - 5.2e-24 84.8 0.0 6.9e-24 84.4 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 KXH51311.1 - 8.2e-06 25.7 0.0 9.9e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold preATP-grasp_3 PF18301.1 KXH51311.1 - 0.14 12.5 0.0 0.24 11.7 0.0 1.5 1 0 0 1 1 1 0 pre ATP-grasp 3 domain Glyco_hydro_cc PF11790.8 KXH51313.1 - 7e-62 209.1 0.0 8.1e-62 208.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core SKG6 PF08693.10 KXH51314.1 - 2.2e-05 23.8 0.3 4e-05 22.9 0.3 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain TMEM51 PF15345.6 KXH51314.1 - 0.12 12.2 0.0 0.15 11.9 0.0 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 NPP1 PF05630.11 KXH51315.1 - 1e-50 172.6 0.0 1.2e-50 172.3 0.0 1.1 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) NPP1 PF05630.11 KXH51316.1 - 4.3e-41 141.2 0.0 5.5e-41 140.9 0.0 1.1 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) NPP1 PF05630.11 KXH51318.1 - 2.3e-50 171.5 0.0 3.3e-50 170.9 0.0 1.2 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) PhyH PF05721.13 KXH51319.1 - 1.4e-09 38.6 0.0 4e-09 37.0 0.0 1.8 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Fungal_trans_2 PF11951.8 KXH51320.1 - 2.9e-08 33.0 0.0 5.1e-08 32.1 0.0 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zip PF02535.22 KXH51321.1 - 6.2e-49 167.0 3.0 6.2e-49 167.0 3.0 1.4 2 0 0 2 2 2 1 ZIP Zinc transporter Cyt-b5 PF00173.28 KXH51335.1 - 1.3e-17 63.7 0.0 3.2e-17 62.4 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_desaturase PF00487.24 KXH51335.1 - 1.7e-17 64.1 14.4 1.7e-17 64.1 14.4 1.6 1 1 0 1 1 1 1 Fatty acid desaturase Pkinase PF00069.25 KXH51336.1 - 2.1e-12 47.0 0.0 1.8e-11 43.9 0.0 2.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXH51336.1 - 1.1e-09 37.9 0.0 1.6e-08 34.2 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Lon_C PF05362.13 KXH51337.1 - 3.8e-64 216.0 0.0 6.6e-64 215.2 0.0 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 KXH51337.1 - 9.2e-35 120.4 0.1 3.8e-34 118.4 0.1 2.1 1 1 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 KXH51337.1 - 7.2e-22 78.2 0.0 2.2e-21 76.6 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 KXH51337.1 - 7.3e-07 29.5 0.0 3.5e-06 27.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 KXH51337.1 - 1.1e-06 28.7 0.0 3.1e-06 27.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.6 KXH51337.1 - 1.4e-06 28.2 0.0 3.6e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_22 PF13401.6 KXH51337.1 - 3e-05 24.3 0.0 0.00048 20.4 0.0 2.6 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 KXH51337.1 - 0.00015 21.6 0.0 0.00097 18.9 0.0 2.4 4 0 0 4 4 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_PrkA PF08298.11 KXH51337.1 - 0.00021 20.4 0.0 0.00039 19.5 0.0 1.4 1 0 0 1 1 1 1 PrkA AAA domain AAA_16 PF13191.6 KXH51337.1 - 0.00038 20.9 1.4 0.002 18.5 0.0 2.6 2 1 1 3 3 2 1 AAA ATPase domain AAA_18 PF13238.6 KXH51337.1 - 0.0012 19.4 0.4 0.014 15.9 0.0 2.9 3 0 0 3 3 3 1 AAA domain IstB_IS21 PF01695.17 KXH51337.1 - 0.0053 16.5 0.7 0.053 13.2 0.0 2.6 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_14 PF13173.6 KXH51337.1 - 0.0056 16.7 0.0 0.03 14.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KXH51337.1 - 0.03 14.7 0.0 0.1 13.0 0.0 2.0 1 0 0 1 1 1 0 RNA helicase RsgA_GTPase PF03193.16 KXH51337.1 - 0.036 14.0 0.0 0.11 12.4 0.0 1.8 1 0 0 1 1 1 0 RsgA GTPase AAA_28 PF13521.6 KXH51337.1 - 0.049 13.9 0.2 5 7.4 0.0 3.1 3 0 0 3 3 3 0 AAA domain DNTTIP1_dimer PF18192.1 KXH51337.1 - 0.05 14.0 0.2 1.3 9.4 0.0 3.0 2 1 0 2 2 2 0 DNTTIP1 dimerisation domain AAA_30 PF13604.6 KXH51337.1 - 0.051 13.3 0.0 0.14 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KXH51337.1 - 0.061 13.2 0.3 1.2 9.1 0.0 2.6 1 1 1 2 2 2 0 NTPase AAA_7 PF12775.7 KXH51337.1 - 0.089 12.3 1.1 0.18 11.3 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region AbrB_C PF18277.1 KXH51337.1 - 0.089 12.4 0.1 0.65 9.7 0.1 2.5 2 0 0 2 2 2 0 AbrB C-terminal domain CAC1F_C PF16885.5 KXH51337.1 - 0.13 11.9 0.1 0.13 11.9 0.1 2.4 3 0 0 3 3 2 0 Voltage-gated calcium channel subunit alpha, C-term MMR_HSR1 PF01926.23 KXH51337.1 - 0.18 11.9 0.7 9 6.4 0.0 3.0 2 0 0 2 2 2 0 50S ribosome-binding GTPase ClpB_D2-small PF10431.9 KXH51337.1 - 0.55 10.3 5.2 0.21 11.6 0.5 2.5 2 0 0 2 2 2 0 C-terminal, D2-small domain, of ClpB protein ABC_tran PF00005.27 KXH51337.1 - 0.8 10.2 4.8 0.72 10.4 0.1 2.9 3 0 0 3 3 3 0 ABC transporter FAM176 PF14851.6 KXH51338.1 - 0.21 11.2 6.2 0.16 11.7 0.3 2.1 2 0 0 2 2 2 0 FAM176 family TFB6 PF17110.5 KXH51338.1 - 0.52 10.0 6.4 0.66 9.7 1.0 2.1 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH TLP-20 PF06088.11 KXH51338.1 - 1.7 8.5 7.7 0.4 10.6 2.3 2.0 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) eIF3_subunit PF08597.10 KXH51338.1 - 3.1 7.6 25.4 0.11 12.4 8.5 2.1 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit GST_N_3 PF13417.6 KXH51339.1 - 5.6e-13 49.1 0.0 8.3e-13 48.6 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KXH51339.1 - 2.2e-12 47.2 0.1 4e-12 46.3 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KXH51339.1 - 2.6e-08 34.0 0.1 4.3e-08 33.3 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KXH51339.1 - 0.00019 21.6 0.0 0.00033 20.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KXH51339.1 - 0.0069 16.5 0.0 0.011 15.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KXH51339.1 - 0.086 12.9 0.0 0.25 11.4 0.0 1.7 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 KXH51339.1 - 0.096 13.0 0.0 0.13 12.6 0.0 1.2 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein G-alpha PF00503.20 KXH51340.1 - 3e-116 388.4 0.8 3.5e-116 388.2 0.8 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KXH51340.1 - 1.8e-15 56.8 0.4 5e-10 39.1 0.2 2.6 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KXH51340.1 - 0.0021 17.5 4.2 0.095 12.0 0.1 2.5 1 1 1 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 KXH51340.1 - 0.0038 17.4 0.5 1.3 9.3 0.1 2.6 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 KXH51340.1 - 0.1 12.4 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Phosphorylase PF00343.20 KXH51341.1 - 0 1054.6 0.0 0 1054.4 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase DUF3433 PF11915.8 KXH51358.1 - 2.1e-35 121.1 22.4 1.4e-19 70.3 2.2 3.8 4 0 0 4 4 4 2 Protein of unknown function (DUF3433) SPX PF03105.19 KXH51358.1 - 3.7 7.4 6.1 6.3 6.6 6.1 1.3 1 0 0 1 1 1 0 SPX domain TRP PF06011.12 KXH51359.1 - 1.9e-165 550.7 34.9 2.3e-165 550.5 34.9 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 KXH51359.1 - 4e-43 147.1 0.8 6.7e-43 146.4 0.8 1.4 1 0 0 1 1 1 1 ML-like domain TcpE PF12648.7 KXH51359.1 - 2 9.0 12.3 3.8 8.1 0.8 3.1 2 1 0 2 2 2 0 TcpE family DHO_dh PF01180.21 KXH51363.1 - 2.4e-18 66.4 0.0 1.3e-17 63.9 0.0 1.8 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase NMO PF03060.15 KXH51363.1 - 0.00073 19.0 0.7 0.0011 18.5 0.7 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase His_biosynth PF00977.21 KXH51363.1 - 0.084 12.3 0.2 0.15 11.5 0.2 1.3 1 0 0 1 1 1 0 Histidine biosynthesis protein Croc_4 PF17691.1 KXH51363.1 - 0.087 12.9 0.7 0.15 12.1 0.7 1.4 1 0 0 1 1 1 0 Contingent replication of cDNA 4 MFS_1 PF07690.16 KXH51364.1 - 1.3e-11 44.0 37.6 5.8e-10 38.6 17.7 4.5 3 2 1 4 4 4 3 Major Facilitator Superfamily Asp-B-Hydro_N PF05279.11 KXH51364.1 - 0.26 11.3 0.0 0.41 10.7 0.0 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Fungal_trans PF04082.18 KXH51365.1 - 9e-27 93.8 0.0 1.5e-26 93.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH51365.1 - 1e-05 25.5 15.8 1.7e-05 24.8 15.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DHquinase_I PF01487.15 KXH51367.1 - 9e-45 153.7 0.0 1.4e-44 153.1 0.0 1.3 1 0 0 1 1 1 1 Type I 3-dehydroquinase MFS_1 PF07690.16 KXH51370.1 - 2.5e-32 112.2 54.0 2.5e-32 112.2 54.0 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH51370.1 - 2.2e-09 36.7 12.7 2.2e-09 36.7 12.7 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 KXH51370.1 - 0.54 8.5 15.0 0.026 12.8 3.9 2.8 3 1 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Glyco_transf_90 PF05686.12 KXH51372.1 - 5.6e-09 35.4 0.1 3.5e-06 26.2 0.0 3.2 2 2 0 2 2 2 1 Glycosyl transferase family 90 Tctex-1 PF03645.13 KXH51374.1 - 7.4e-40 135.4 0.0 8.5e-40 135.2 0.0 1.0 1 0 0 1 1 1 1 Tctex-1 family PmbA_TldD PF01523.16 KXH51374.1 - 0.046 13.6 0.1 0.053 13.4 0.1 1.1 1 0 0 1 1 1 0 Putative modulator of DNA gyrase DUF202 PF02656.15 KXH51375.1 - 8.4e-16 58.2 3.5 8.4e-16 58.2 3.5 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Alba PF01918.21 KXH51376.1 - 0.0005 19.8 0.3 0.0015 18.3 0.1 1.9 2 0 0 2 2 2 1 Alba Mucin PF01456.17 KXH51376.1 - 2.9 7.9 17.4 5.9 6.9 17.4 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein CFEM PF05730.11 KXH51378.1 - 0.12 12.4 13.6 0.25 11.5 13.5 1.8 1 1 0 1 1 1 0 CFEM domain FliD_N PF02465.18 KXH51378.1 - 1 10.1 16.0 6.4 7.5 16.0 2.1 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus Macoilin PF09726.9 KXH51378.1 - 1.2 7.6 3.6 1.2 7.6 3.6 1.1 1 0 0 1 1 1 0 Macoilin family FSA_C PF10479.9 KXH51378.1 - 7.8 4.5 11.0 8.2 4.4 11.0 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Ion_trans PF00520.31 KXH51379.1 - 2.2e-08 33.6 3.3 3e-08 33.2 3.3 1.1 1 0 0 1 1 1 1 Ion transport protein RRM_1 PF00076.22 KXH51380.1 - 1.4e-16 60.1 0.0 2.1e-16 59.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spc7 PF08317.11 KXH51380.1 - 0.026 13.4 2.4 0.032 13.1 2.4 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Nup35_RRM_2 PF14605.6 KXH51380.1 - 0.034 14.1 0.0 0.066 13.2 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif BLOC1_2 PF10046.9 KXH51380.1 - 0.038 14.3 0.3 0.06 13.7 0.3 1.3 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF724 PF05266.14 KXH51380.1 - 0.067 13.0 3.5 0.089 12.6 3.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) GPS2_interact PF15784.5 KXH51380.1 - 0.091 13.2 1.7 0.15 12.5 1.7 1.4 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain RRM_occluded PF16842.5 KXH51380.1 - 0.15 11.9 0.0 0.31 10.9 0.0 1.6 1 1 0 1 1 1 0 Occluded RNA-recognition motif V_ATPase_I PF01496.19 KXH51380.1 - 0.19 9.6 1.0 0.22 9.4 1.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family EMP24_GP25L PF01105.24 KXH51380.1 - 0.23 11.4 1.8 0.33 10.9 1.8 1.1 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD UPF0242 PF06785.11 KXH51380.1 - 0.37 10.9 2.4 0.48 10.5 2.4 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus APG6_N PF17675.1 KXH51380.1 - 0.69 10.4 6.9 0.97 10.0 6.9 1.1 1 0 0 1 1 1 0 Apg6 coiled-coil region DivIC PF04977.15 KXH51380.1 - 1.5 8.6 4.7 2.4 8.0 4.7 1.2 1 0 0 1 1 1 0 Septum formation initiator HECT PF00632.25 KXH51382.1 - 1.3e-94 317.1 0.0 1.8e-94 316.7 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 KXH51382.1 - 1.4e-34 117.8 24.7 6.9e-13 48.4 6.3 3.9 4 0 0 4 4 4 3 WW domain C2 PF00168.30 KXH51382.1 - 7.7e-19 67.9 0.1 2.3e-18 66.3 0.1 1.9 1 0 0 1 1 1 1 C2 domain Oxidored_q6 PF01058.22 KXH51383.1 - 1.2e-22 80.2 0.1 1.8e-22 79.6 0.1 1.3 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit p450 PF00067.22 KXH51385.1 - 5e-51 173.9 0.0 1e-50 172.9 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 RVT_connect PF06815.13 KXH51385.1 - 0.16 12.3 3.0 0.28 11.4 2.1 1.9 2 0 0 2 2 2 0 Reverse transcriptase connection domain cEGF PF12662.7 KXH51386.1 - 0.24 11.4 4.8 2.2 8.3 1.1 3.0 2 1 0 2 2 2 0 Complement Clr-like EGF-like Ceramidase_alk PF04734.13 KXH51387.1 - 3.5e-225 748.4 0.0 4.1e-225 748.2 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 KXH51387.1 - 2.2e-60 203.3 0.1 3.5e-60 202.7 0.1 1.3 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal SBP56 PF05694.11 KXH51388.1 - 0.0013 17.6 0.0 0.022 13.6 0.0 2.2 1 1 0 1 1 1 1 56kDa selenium binding protein (SBP56) NHL PF01436.21 KXH51388.1 - 0.16 12.1 0.0 0.51 10.5 0.0 1.9 1 0 0 1 1 1 0 NHL repeat Cupin_1 PF00190.22 KXH51389.1 - 1.7e-39 134.8 0.0 1.9e-20 73.0 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 KXH51389.1 - 2.9e-23 81.4 1.1 3.5e-13 49.1 0.0 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 KXH51389.1 - 3.6e-06 26.6 0.1 0.025 14.3 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.19 KXH51389.1 - 0.0013 18.7 0.1 0.17 11.8 0.0 2.7 3 0 0 3 3 3 2 AraC-like ligand binding domain Endosulfine PF04667.17 KXH51390.1 - 3.3e-28 97.7 0.1 5e-28 97.0 0.1 1.3 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region UPF0160 PF03690.13 KXH51391.1 - 3.2e-131 437.7 0.0 3.6e-131 437.5 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) Ino80_Iec3 PF14612.6 KXH51392.1 - 2e-52 179.2 10.4 5.2e-28 99.3 1.2 2.6 2 1 1 3 3 3 2 IEC3 subunit of the Ino80 complex, chromatin re-modelling Iso_dh PF00180.20 KXH51393.1 - 5.7e-73 246.1 0.0 6.8e-73 245.8 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Not3 PF04065.15 KXH51396.1 - 5.8e-90 300.7 25.4 5.8e-90 300.7 25.4 1.9 2 0 0 2 2 2 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 KXH51396.1 - 2.4e-42 144.1 5.8 7.1e-42 142.6 5.8 1.8 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Syntaxin_2 PF14523.6 KXH51396.1 - 0.0053 17.1 3.4 0.0053 17.1 3.4 2.8 3 0 0 3 3 3 1 Syntaxin-like protein DUF1192 PF06698.11 KXH51396.1 - 0.0099 15.9 1.9 0.0099 15.9 1.9 3.5 4 0 0 4 4 2 1 Protein of unknown function (DUF1192) DUF2373 PF10180.9 KXH51396.1 - 0.026 14.3 3.7 0.059 13.2 3.7 1.6 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2373) HUN PF08729.10 KXH51396.1 - 0.082 12.9 1.5 0.22 11.5 1.5 1.7 1 0 0 1 1 1 0 HPC2 and ubinuclein domain SNARE PF05739.19 KXH51396.1 - 0.12 12.4 1.5 0.3 11.1 0.4 2.2 2 0 0 2 2 2 0 SNARE domain Cep57_MT_bd PF06657.13 KXH51396.1 - 0.19 12.2 10.8 1.1 9.8 2.0 3.0 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 JIP_LZII PF16471.5 KXH51396.1 - 0.87 9.8 7.2 0.19 11.9 1.3 2.6 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II Sec5 PF15469.6 KXH51396.1 - 1.5 8.6 11.0 0.32 10.8 1.6 2.4 2 0 0 2 2 2 0 Exocyst complex component Sec5 DUF2937 PF11157.8 KXH51396.1 - 1.9 8.2 4.0 25 4.6 0.4 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF2937) Nnf1 PF03980.14 KXH51396.1 - 2.6 8.5 14.5 1.8 8.9 9.2 3.2 2 1 1 3 3 3 0 Nnf1 CorA PF01544.18 KXH51396.1 - 3 7.1 6.6 0.71 9.1 2.2 1.9 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein 4HB_MCP_1 PF12729.7 KXH51396.1 - 4.7 6.7 15.5 3.1 7.3 8.2 2.4 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction Tyr_Deacylase PF02580.16 KXH51397.1 - 2.1e-47 161.3 0.0 2.3e-47 161.1 0.0 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Telomere_reg-2 PF10193.9 KXH51397.1 - 0.024 15.1 0.0 0.07 13.6 0.0 1.7 2 0 0 2 2 2 0 Telomere length regulation protein Pro_isomerase PF00160.21 KXH51398.1 - 1.6e-47 161.7 0.1 2.4e-47 161.2 0.1 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_2 PF07719.17 KXH51398.1 - 1.6e-06 27.7 6.8 9.2e-05 22.3 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KXH51398.1 - 0.00019 21.1 5.2 0.00027 20.6 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 KXH51398.1 - 0.011 15.9 0.0 0.047 13.9 0.0 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_9 PF13371.6 KXH51398.1 - 0.013 15.6 0.1 0.042 14.0 0.1 1.9 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_16 PF13432.6 KXH51398.1 - 0.015 15.9 1.0 0.015 15.9 1.0 2.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 KXH51398.1 - 0.02 14.6 1.3 2.7 7.8 0.0 3.4 2 1 1 3 3 3 0 TPR repeat TPR_14 PF13428.6 KXH51398.1 - 0.083 13.8 0.1 0.37 11.7 0.1 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.6 KXH51398.1 - 0.51 11.1 2.8 0.56 11.0 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat RasGAP PF00616.19 KXH51399.1 - 1.5e-28 100.0 0.0 2.4e-20 73.2 0.0 2.5 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase C2 PF00168.30 KXH51399.1 - 0.0029 17.9 0.0 0.0067 16.7 0.0 1.7 1 1 0 1 1 1 1 C2 domain Glyco_hydro_47 PF01532.20 KXH51401.1 - 1.1e-171 571.8 0.0 1.2e-171 571.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_76 PF03663.14 KXH51401.1 - 0.046 13.2 0.0 0.7 9.3 0.0 2.2 2 0 0 2 2 2 0 Glycosyl hydrolase family 76 UPF1_Zn_bind PF09416.10 KXH51402.1 - 6.3e-71 237.3 2.6 2.3e-70 235.5 1.2 2.2 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.6 KXH51402.1 - 2.7e-60 203.4 0.0 5.4e-60 202.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KXH51402.1 - 1.5e-53 182.2 2.7 1.1e-30 107.4 0.2 2.3 1 1 1 2 2 2 2 AAA domain DUF5599 PF18141.1 KXH51402.1 - 1.5e-32 111.7 0.0 2.8e-32 110.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5599) AAA_30 PF13604.6 KXH51402.1 - 4.6e-13 49.3 0.3 7.8e-12 45.3 0.3 2.2 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KXH51402.1 - 8.7e-10 39.1 0.1 2.8e-09 37.5 0.1 1.8 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 KXH51402.1 - 6.4e-05 23.0 0.0 0.00012 22.2 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.18 KXH51402.1 - 0.00011 22.0 0.1 0.43 10.3 0.0 2.9 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.14 KXH51402.1 - 0.00012 21.9 0.0 0.00024 21.0 0.0 1.5 1 0 0 1 1 1 1 Helicase DUF2075 PF09848.9 KXH51402.1 - 0.00051 19.4 0.2 0.014 14.6 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) PIF1 PF05970.14 KXH51402.1 - 0.00081 18.7 0.0 0.27 10.3 0.0 2.2 2 0 0 2 2 2 2 PIF1-like helicase UvrD-helicase PF00580.21 KXH51402.1 - 0.0014 18.3 0.0 0.029 13.9 0.1 2.2 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain DEAD PF00270.29 KXH51402.1 - 0.006 16.4 0.1 0.013 15.3 0.1 1.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_10 PF12846.7 KXH51402.1 - 0.014 14.4 0.0 0.022 13.7 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_22 PF13401.6 KXH51402.1 - 0.016 15.5 0.0 0.069 13.4 0.0 2.0 2 0 0 2 2 1 0 AAA domain SRP54 PF00448.22 KXH51402.1 - 0.018 14.7 0.0 0.037 13.6 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ATPase PF06745.13 KXH51402.1 - 0.032 13.6 0.0 0.064 12.6 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_16 PF13191.6 KXH51402.1 - 0.074 13.4 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain PhoH PF02562.16 KXH51402.1 - 0.093 12.2 0.0 0.26 10.7 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein Brix PF04427.18 KXH51403.1 - 2.2e-30 106.2 0.1 2.9e-30 105.8 0.1 1.1 1 0 0 1 1 1 1 Brix domain CTNNBL PF08216.11 KXH51403.1 - 0.095 12.9 0.1 0.2 11.8 0.1 1.5 1 0 0 1 1 1 0 Catenin-beta-like, Arm-motif containing nuclear Syntaxin PF00804.25 KXH51404.1 - 4.2e-27 95.1 9.3 4.2e-27 95.1 9.3 1.8 2 0 0 2 2 2 1 Syntaxin SNARE PF05739.19 KXH51404.1 - 1.2e-10 41.2 0.3 1.2e-10 41.2 0.3 2.3 3 0 0 3 3 2 1 SNARE domain Syntaxin_2 PF14523.6 KXH51404.1 - 3.3e-05 24.2 14.1 0.00019 21.7 5.4 2.4 2 0 0 2 2 2 2 Syntaxin-like protein FUSC PF04632.12 KXH51404.1 - 0.0042 15.7 10.5 0.028 13.0 1.3 2.1 1 1 1 2 2 2 2 Fusaric acid resistance protein family Fer4_24 PF18109.1 KXH51404.1 - 0.0052 17.0 0.9 0.011 16.0 0.1 2.0 2 0 0 2 2 1 1 Ferredoxin I 4Fe-4S cluster domain MCU PF04678.13 KXH51404.1 - 0.0066 16.6 1.6 0.0066 16.6 1.6 2.2 2 0 0 2 2 2 1 Mitochondrial calcium uniporter ETRAMP PF09716.10 KXH51404.1 - 0.021 14.9 0.0 0.028 14.5 0.0 1.5 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) IZUMO PF15005.6 KXH51404.1 - 0.07 13.7 3.4 1.6 9.2 0.1 2.3 2 0 0 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated Holin_2-3 PF13272.6 KXH51404.1 - 0.098 13.0 0.1 0.19 12.0 0.1 1.5 1 0 0 1 1 1 0 Putative 2/3 transmembrane domain holin LMBR1 PF04791.16 KXH51404.1 - 0.17 10.7 1.9 0.25 10.2 1.9 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Mod_r PF07200.13 KXH51404.1 - 0.3 11.2 16.5 1.3 9.2 6.9 2.7 2 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF2207 PF09972.9 KXH51404.1 - 0.34 9.6 5.0 0.38 9.4 0.0 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) Use1 PF09753.9 KXH51404.1 - 0.48 10.1 12.9 0.9 9.2 12.9 1.5 1 1 0 1 1 1 0 Membrane fusion protein Use1 DotU PF09850.9 KXH51404.1 - 0.82 9.3 4.8 0.16 11.7 0.2 2.1 3 0 0 3 3 3 0 Type VI secretion system protein DotU Allexi_40kDa PF05549.11 KXH51404.1 - 0.83 9.1 8.2 1 8.8 1.2 2.1 2 0 0 2 2 2 0 Allexivirus 40kDa protein Spc42p PF11544.8 KXH51404.1 - 0.98 9.5 5.5 0.32 11.0 1.4 2.3 2 0 0 2 2 2 0 Spindle pole body component Spc42p PBC PF03792.13 KXH51404.1 - 1.8 8.3 10.4 0.18 11.6 2.7 2.3 1 1 0 2 2 2 0 PBC domain JIP_LZII PF16471.5 KXH51404.1 - 4 7.7 10.5 11 6.2 0.0 3.8 4 1 0 4 4 4 0 JNK-interacting protein leucine zipper II Baculo_PEP_C PF04513.12 KXH51404.1 - 4.2 7.4 13.3 7.3 6.6 3.7 3.0 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus SKA1 PF07160.12 KXH51404.1 - 4.3 7.1 13.4 0.31 10.8 3.3 2.3 1 1 2 3 3 3 0 Spindle and kinetochore-associated protein 1 TPR_1 PF00515.28 KXH51405.1 - 2.7e-48 159.9 20.0 3.4e-06 26.6 0.0 11.5 11 0 0 11 11 11 10 Tetratricopeptide repeat TPR_2 PF07719.17 KXH51405.1 - 2.1e-44 146.1 17.2 0.00015 21.6 0.0 11.4 11 0 0 11 11 11 10 Tetratricopeptide repeat TPR_11 PF13414.6 KXH51405.1 - 3e-26 90.8 16.7 2e-05 24.2 0.0 8.7 5 2 3 8 8 8 6 TPR repeat TPR_8 PF13181.6 KXH51405.1 - 1.2e-24 84.4 19.6 0.0046 17.1 0.0 11.2 11 0 0 11 11 11 6 Tetratricopeptide repeat TPR_17 PF13431.6 KXH51405.1 - 3.8e-23 80.1 7.7 7.1e-05 22.9 0.0 9.1 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_16 PF13432.6 KXH51405.1 - 2.1e-22 79.5 12.1 0.00016 22.3 0.1 7.3 6 2 1 8 8 7 5 Tetratricopeptide repeat TPR_12 PF13424.6 KXH51405.1 - 5.6e-21 74.6 22.0 0.00085 19.6 1.7 9.2 3 3 6 9 9 9 8 Tetratricopeptide repeat TPR_19 PF14559.6 KXH51405.1 - 9.3e-16 58.1 17.5 2.6e-05 24.6 1.0 6.8 6 1 0 6 6 6 3 Tetratricopeptide repeat TPR_9 PF13371.6 KXH51405.1 - 1.2e-12 47.8 7.3 3e-05 24.1 0.0 5.8 5 2 1 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 KXH51405.1 - 4.7e-12 45.7 21.2 0.027 15.3 0.6 9.5 4 3 8 12 12 10 3 Tetratricopeptide repeat TPR_7 PF13176.6 KXH51405.1 - 8.6e-11 41.1 17.5 0.022 14.7 0.1 9.5 8 2 2 10 10 10 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KXH51405.1 - 3.8e-08 33.1 0.8 1.5e-07 31.1 0.6 2.0 1 1 1 2 2 2 1 MalT-like TPR region ANAPC3 PF12895.7 KXH51405.1 - 1.1e-07 31.9 10.2 0.14 12.4 0.1 5.9 2 2 4 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 KXH51405.1 - 2.3e-07 30.4 17.4 0.031 14.2 0.4 8.8 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_15 PF13429.6 KXH51405.1 - 3.5e-07 29.7 1.6 0.082 12.1 0.3 4.4 2 1 2 4 4 4 3 Tetratricopeptide repeat SHNi-TPR PF10516.9 KXH51405.1 - 5.5e-07 28.9 7.1 0.11 12.0 0.0 5.9 6 0 0 6 6 6 2 SHNi-TPR TPR_6 PF13174.6 KXH51405.1 - 1.3e-05 25.5 17.4 13 6.7 0.0 8.8 9 0 0 9 9 8 0 Tetratricopeptide repeat MIT PF04212.18 KXH51405.1 - 0.004 17.2 10.7 13 5.9 0.1 6.0 6 0 0 6 6 6 0 MIT (microtubule interacting and transport) domain TPR_4 PF07721.14 KXH51405.1 - 0.016 15.8 0.5 1e+02 4.0 0.0 5.0 4 1 1 5 5 5 0 Tetratricopeptide repeat DUF3856 PF12968.7 KXH51405.1 - 0.016 15.2 7.0 5.5 7.1 0.0 5.9 4 2 2 6 6 6 0 Domain of Unknown Function (DUF3856) TAF1_subA PF14929.6 KXH51405.1 - 0.026 14.0 1.8 0.097 12.1 0.2 2.3 2 1 1 3 3 3 0 TAF RNA Polymerase I subunit A MAS20 PF02064.15 KXH51405.1 - 0.056 13.5 11.2 0.66 10.1 1.0 4.4 4 1 1 5 5 4 0 MAS20 protein import receptor HrpB1_HrpK PF09613.10 KXH51405.1 - 0.08 12.6 0.3 0.69 9.6 0.2 2.2 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) Sel1 PF08238.12 KXH51405.1 - 0.09 13.5 6.8 1.8 9.4 0.1 4.7 5 0 0 5 5 3 0 Sel1 repeat TPR_3 PF07720.12 KXH51405.1 - 0.45 10.5 14.5 0.42 10.7 0.3 5.6 6 0 0 6 6 5 0 Tetratricopeptide repeat Foie-gras_1 PF11817.8 KXH51405.1 - 0.48 10.0 3.9 0.35 10.4 0.7 2.3 3 0 0 3 3 2 0 Foie gras liver health family 1 NARP1 PF12569.8 KXH51405.1 - 0.79 8.6 25.1 0.36 9.7 0.3 4.8 3 2 1 5 5 5 0 NMDA receptor-regulated protein 1 Aminotran_4 PF01063.19 KXH51406.1 - 1.6e-21 77.2 0.0 2.6e-21 76.5 0.0 1.2 1 0 0 1 1 1 1 Amino-transferase class IV Asp PF00026.23 KXH51407.1 - 2.9e-69 233.9 1.9 3.8e-69 233.5 1.9 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KXH51407.1 - 2.4e-15 57.2 4.6 4.4e-10 40.1 0.0 2.8 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KXH51407.1 - 0.00036 21.1 0.9 0.73 10.5 0.2 3.0 2 1 0 2 2 2 2 Aspartyl protease Btz PF09405.10 KXH51408.1 - 4.8e-27 94.8 1.5 1.3e-26 93.4 1.5 1.7 1 0 0 1 1 1 1 CASC3/Barentsz eIF4AIII binding zf-C3HC PF07967.13 KXH51412.1 - 0.16 12.0 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 C3HC zinc finger-like FAD_binding_2 PF00890.24 KXH51414.1 - 7.7e-77 259.1 0.7 8.9e-77 258.9 0.7 1.0 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KXH51414.1 - 9.4e-09 35.1 1.8 1.4e-08 34.5 1.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXH51414.1 - 8.9e-07 29.1 1.3 3.1e-06 27.3 1.3 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KXH51414.1 - 6.4e-05 21.8 0.9 9.8e-05 21.2 0.9 1.2 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.17 KXH51414.1 - 0.00012 21.4 1.5 0.00083 18.7 0.2 2.2 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 KXH51414.1 - 0.00012 21.7 2.2 0.00058 19.5 0.9 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXH51414.1 - 0.00044 19.6 1.0 0.00069 18.9 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXH51414.1 - 0.0024 18.4 0.1 0.005 17.4 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KXH51414.1 - 0.0067 15.6 0.3 0.018 14.2 0.6 1.5 2 0 0 2 2 2 1 Glucose inhibited division protein A XdhC_C PF13478.6 KXH51414.1 - 0.015 15.8 0.0 1.2 9.7 0.0 2.4 2 0 0 2 2 2 0 XdhC Rossmann domain AlaDh_PNT_C PF01262.21 KXH51414.1 - 0.016 14.5 1.8 0.023 14.0 0.2 1.9 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 KXH51414.1 - 0.018 14.3 0.1 0.027 13.7 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KXH51414.1 - 0.036 13.1 0.3 0.052 12.6 0.3 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein DUF3659 PF12396.8 KXH51414.1 - 0.081 12.9 1.8 0.093 12.7 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3659) Peptidase_A4 PF01828.17 KXH51495.1 - 1.6e-69 233.6 16.5 1.9e-69 233.3 16.5 1.1 1 0 0 1 1 1 1 Peptidase A4 family CARDB PF07705.11 KXH51495.1 - 0.12 12.6 2.3 0.27 11.5 0.3 2.5 2 1 0 2 2 2 0 CARDB PASTA PF03793.19 KXH51495.1 - 0.49 10.3 3.5 1.5 8.7 0.5 3.2 4 0 0 4 4 4 0 PASTA domain Peptidase_S10 PF00450.22 KXH51496.1 - 3.8e-78 263.8 1.8 5.2e-78 263.3 1.8 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.7 KXH51496.1 - 0.0031 18.1 0.1 0.0056 17.3 0.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family HET PF06985.11 KXH51497.1 - 1.7e-26 93.3 0.0 3.6e-26 92.3 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Peptidase_C14 PF00656.22 KXH51498.1 - 6.5e-25 88.5 0.0 1e-24 87.8 0.0 1.3 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.6 KXH51498.1 - 0.19 11.6 0.0 0.85 9.6 0.0 2.0 1 1 0 1 1 1 0 Raptor N-terminal CASPase like domain Pyridoxal_deC PF00282.19 KXH51499.1 - 2.3e-22 79.3 0.0 5.8e-14 51.6 0.0 3.0 2 1 0 2 2 2 2 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 KXH51499.1 - 0.04 13.2 0.0 0.07 12.4 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase CHAT PF12770.7 KXH51501.1 - 4.8e-35 121.4 0.0 9.3e-35 120.4 0.0 1.5 1 0 0 1 1 1 1 CHAT domain ANAPC5 PF12862.7 KXH51501.1 - 0.031 14.4 0.8 0.43 10.7 0.0 3.3 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 5 Peptidase_C50 PF03568.17 KXH51501.1 - 0.11 11.6 0.0 0.26 10.4 0.0 1.6 1 0 0 1 1 1 0 Peptidase family C50 Peptidase_C14 PF00656.22 KXH51501.1 - 0.18 11.7 0.0 0.45 10.4 0.0 1.6 1 0 0 1 1 1 0 Caspase domain ECH_1 PF00378.20 KXH51502.1 - 2e-26 92.9 0.0 2.5e-26 92.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXH51502.1 - 4.2e-09 36.4 0.0 6.3e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Sialidase PF02973.16 KXH51502.1 - 0.16 11.4 0.5 9.7 5.6 0.1 2.4 2 1 1 3 3 3 0 Sialidase, N-terminal domain adh_short PF00106.25 KXH51503.1 - 5.8e-22 78.1 0.0 4.7e-20 71.9 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXH51503.1 - 1.7e-10 40.9 0.0 4.1e-09 36.4 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH51503.1 - 8.7e-07 29.0 0.0 1.8e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KXH51503.1 - 0.0075 15.4 0.0 0.011 14.9 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KXH51503.1 - 0.092 12.2 0.0 0.21 11.0 0.0 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family LOR PF04525.12 KXH51504.1 - 1.3e-20 73.8 0.0 1.6e-20 73.5 0.0 1.0 1 0 0 1 1 1 1 LURP-one-related Bac_rhamnosid6H PF17389.2 KXH51505.1 - 4.5e-11 42.6 0.1 3.7e-10 39.6 0.2 2.2 2 1 0 2 2 2 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_C PF17390.2 KXH51505.1 - 5.7e-06 26.0 0.1 1.9e-05 24.4 0.1 1.9 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain Trehalase PF01204.18 KXH51505.1 - 0.013 14.3 0.0 0.02 13.8 0.0 1.1 1 0 0 1 1 1 0 Trehalase YCII PF03795.14 KXH51506.1 - 3.4e-10 40.2 0.0 4.3e-10 39.9 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain Fungal_trans PF04082.18 KXH51507.1 - 1.8e-14 53.4 0.0 3.9e-14 52.3 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH51507.1 - 0.0088 16.2 5.0 0.016 15.3 5.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SelP_N PF04592.14 KXH51507.1 - 1.4 8.3 4.5 2.9 7.2 4.5 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Flavin_Reduct PF01613.18 KXH51508.1 - 8.9e-19 68.0 0.0 1.2e-18 67.7 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain Polyoma_lg_T_C PF06431.11 KXH51509.1 - 0.046 12.6 0.0 0.063 12.1 0.0 1.1 1 0 0 1 1 1 0 Polyomavirus large T antigen C-terminus Transport_MerF PF11431.8 KXH51509.1 - 0.22 11.5 0.0 0.47 10.4 0.0 1.5 1 0 0 1 1 1 0 Membrane transport protein MerF Pro_dh PF01619.18 KXH51510.1 - 2.1e-64 217.9 0.0 2.5e-64 217.6 0.0 1.1 1 0 0 1 1 1 1 Proline dehydrogenase TraB PF01963.17 KXH51510.1 - 0.043 13.7 0.4 0.19 11.6 0.0 2.0 1 1 1 2 2 2 0 TraB family Tenui_NCP PF04876.12 KXH51510.1 - 0.098 12.2 0.0 0.25 10.9 0.0 1.6 1 1 1 2 2 2 0 Tenuivirus major non-capsid protein MFS_1 PF07690.16 KXH51512.1 - 7.8e-22 77.7 57.2 1.1e-16 60.7 27.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Arrestin_C PF02752.22 KXH51513.1 - 1.3e-10 41.9 0.0 4e-09 37.0 0.0 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 KXH51513.1 - 0.0002 21.4 0.0 0.00041 20.4 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 KXH51513.1 - 0.015 15.0 0.0 0.028 14.1 0.0 1.4 1 0 0 1 1 1 0 Arrestin_N terminal like Exo_endo_phos PF03372.23 KXH51515.1 - 1.8e-06 27.6 0.4 7.4e-06 25.6 0.5 2.1 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 KXH51515.1 - 0.017 15.0 0.0 0.04 13.7 0.0 1.7 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase Hydrolase_4 PF12146.8 KXH51516.1 - 1.5e-06 27.7 0.3 8.5e-06 25.2 0.3 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KXH51516.1 - 4.1e-06 27.6 3.3 6.4e-06 26.9 3.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family LIP PF03583.14 KXH51516.1 - 6.6e-06 25.7 0.1 0.011 15.1 0.2 2.2 2 0 0 2 2 2 2 Secretory lipase Peptidase_S9 PF00326.21 KXH51516.1 - 4.1e-05 23.1 1.3 0.0022 17.5 0.0 2.9 2 1 0 3 3 3 1 Prolyl oligopeptidase family DLH PF01738.18 KXH51516.1 - 0.0026 17.3 0.1 0.04 13.5 0.0 2.2 2 0 0 2 2 2 1 Dienelactone hydrolase family Epimerase PF01370.21 KXH51517.1 - 1.9e-06 27.6 0.0 2.8e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KXH51517.1 - 0.087 12.7 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 KR domain HhH-GPD PF00730.25 KXH51518.1 - 6.3e-09 36.2 0.0 1.6e-08 35.0 0.0 1.7 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein DUF2462 PF09495.10 KXH51518.1 - 0.033 14.9 4.4 0.079 13.7 4.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2462) DUF937 PF06078.11 KXH51518.1 - 0.085 13.5 0.0 0.16 12.6 0.0 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF937) ABC_tran PF00005.27 KXH51519.1 - 1.4e-31 109.9 0.0 3.1e-31 108.7 0.0 1.7 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 KXH51519.1 - 2.5e-23 83.1 3.7 4e-23 82.5 3.7 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 KXH51519.1 - 2.4e-06 27.1 0.0 0.00026 20.5 0.0 2.2 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KXH51519.1 - 0.0024 17.8 0.0 0.007 16.3 0.0 1.8 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 KXH51519.1 - 0.0034 17.7 0.1 0.024 14.9 0.1 2.2 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KXH51519.1 - 0.014 14.7 0.1 0.029 13.6 0.1 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_16 PF13191.6 KXH51519.1 - 0.014 15.8 0.2 0.046 14.1 0.2 1.9 1 1 0 1 1 1 0 AAA ATPase domain AAA_15 PF13175.6 KXH51519.1 - 0.02 14.6 0.0 0.039 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain MMR_HSR1 PF01926.23 KXH51519.1 - 0.021 14.9 0.1 0.23 11.6 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF87 PF01935.17 KXH51519.1 - 0.053 13.6 0.0 0.14 12.2 0.0 1.7 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_21 PF13304.6 KXH51519.1 - 0.07 12.9 0.1 0.43 10.3 0.1 2.1 1 1 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF815 PF05673.13 KXH51519.1 - 0.076 12.2 0.0 0.16 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_29 PF13555.6 KXH51519.1 - 0.15 11.8 0.1 0.46 10.3 0.1 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain PBP1_TM PF14812.6 KXH51519.1 - 0.27 11.6 4.4 0.067 13.6 0.9 1.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FAD_binding_3 PF01494.19 KXH51520.1 - 4.3e-16 59.1 0.0 8.9e-16 58.1 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KXH51520.1 - 6.7e-07 28.8 0.7 0.00082 18.7 0.1 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXH51520.1 - 6.8e-06 25.9 2.9 3.6e-05 23.5 0.8 2.2 1 1 0 2 2 2 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KXH51520.1 - 1.2e-05 24.3 1.1 0.12 11.2 0.4 2.6 2 1 0 3 3 3 2 Tryptophan halogenase FAD_binding_2 PF00890.24 KXH51520.1 - 0.00013 21.2 0.4 0.0002 20.6 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KXH51520.1 - 0.0004 20.6 0.1 0.00082 19.6 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KXH51520.1 - 0.0046 17.5 0.1 0.037 14.6 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXH51520.1 - 0.0053 15.5 0.2 0.012 14.4 0.0 1.6 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.6 KXH51520.1 - 0.054 12.7 0.1 0.1 11.8 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXH51520.1 - 0.093 12.0 0.1 0.2 10.9 0.1 1.4 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.12 KXH51520.1 - 0.39 9.7 1.4 2.4 7.1 1.4 2.1 1 1 0 1 1 1 0 Lycopene cyclase protein PhyH PF05721.13 KXH51521.1 - 9.1e-09 35.9 0.0 1.5e-08 35.1 0.0 1.4 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 KXH51521.1 - 6.5e-05 21.9 0.0 0.069 11.9 0.1 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF1479) 2OG-FeII_Oxy_5 PF13759.6 KXH51521.1 - 0.029 14.8 0.0 0.06 13.8 0.0 1.5 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase MFS_1 PF07690.16 KXH51522.1 - 1.1e-13 50.9 19.9 1.1e-13 50.9 19.9 2.3 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH51522.1 - 9.8e-11 41.2 11.9 2.6e-09 36.4 2.7 3.3 2 2 1 3 3 3 2 Sugar (and other) transporter Peptidase_S15 PF02129.18 KXH51523.1 - 2.5e-37 128.9 0.1 4.6e-36 124.8 0.0 2.1 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 KXH51523.1 - 1.3e-35 123.4 0.0 1.7e-35 123.0 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain PhyH PF05721.13 KXH51524.1 - 0.00071 19.9 0.1 0.002 18.4 0.1 1.8 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 KXH51524.1 - 0.079 11.7 0.1 0.61 8.8 0.1 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1479) Methyltransf_18 PF12847.7 KXH51524.1 - 0.18 11.7 0.0 0.28 11.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Fungal_trans PF04082.18 KXH51525.1 - 1.2e-22 80.3 0.0 2.3e-22 79.3 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH51525.1 - 4.9e-10 39.4 12.0 8.7e-10 38.6 12.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain EndIII_4Fe-2S PF10576.9 KXH51525.1 - 0.86 10.0 3.4 3.1 8.2 3.4 2.1 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III PAS_3 PF08447.12 KXH51527.1 - 0.069 13.5 0.0 0.14 12.5 0.0 1.5 1 0 0 1 1 1 0 PAS fold COesterase PF00135.28 KXH51528.1 - 1.9e-51 175.5 0.0 2.4e-51 175.2 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXH51528.1 - 0.11 12.4 0.7 1.3 8.8 0.7 2.3 1 1 0 1 1 1 0 alpha/beta hydrolase fold GPP34 PF05719.11 KXH51545.1 - 1.3e-70 237.5 0.3 1.7e-70 237.2 0.3 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) Aldo_ket_red PF00248.21 KXH51546.1 - 3.7e-64 216.7 0.0 4.6e-64 216.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family N_NLPC_P60 PF12912.7 KXH51547.1 - 0.074 13.4 1.4 0.1 13.0 0.1 1.8 2 0 0 2 2 2 0 NLPC_P60 stabilising domain, N term Sugar_tr PF00083.24 KXH51548.1 - 3.7e-15 55.8 0.2 4.4e-15 55.5 0.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter Fungal_trans PF04082.18 KXH51549.1 - 3.6e-05 22.9 0.9 5.8e-05 22.3 0.9 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Bromodomain PF00439.25 KXH51550.1 - 5.2e-18 64.9 1.6 6.5e-18 64.6 0.2 1.9 2 0 0 2 2 2 1 Bromodomain Bromo_TP PF07524.13 KXH51550.1 - 4.4e-08 33.0 0.0 8.9e-08 32.0 0.0 1.5 1 0 0 1 1 1 1 Bromodomain associated PSII_Pbs27 PF13326.6 KXH51550.1 - 0.074 13.4 1.2 0.18 12.1 0.6 1.8 1 1 0 1 1 1 0 Photosystem II Pbs27 PBP1_TM PF14812.6 KXH51550.1 - 0.81 10.1 9.2 3.6 8.0 2.3 3.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal VanZ PF04892.12 KXH51551.1 - 3.7e-10 40.5 1.2 5e-10 40.1 1.2 1.2 1 0 0 1 1 1 1 VanZ like family GSAP-16 PF14959.6 KXH51551.1 - 0.032 14.1 0.1 0.046 13.6 0.1 1.2 1 0 0 1 1 1 0 gamma-Secretase-activating protein C-term Ferric_reduct PF01794.19 KXH51552.1 - 3.3e-18 66.0 10.8 3.3e-18 66.0 10.8 1.8 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KXH51552.1 - 1.4e-15 57.7 0.0 2.1e-15 57.2 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KXH51552.1 - 3.2e-07 30.4 0.0 1.8e-06 28.0 0.0 2.1 1 1 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 KXH51552.1 - 5.7e-05 23.7 0.0 0.12 13.1 0.0 2.4 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain DUF4231 PF14015.6 KXH51552.1 - 0.39 11.2 3.4 0.45 11.0 1.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4231) CorA PF01544.18 KXH51553.1 - 0.00071 19.0 3.4 0.0047 16.3 3.4 2.0 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Mit_KHE1 PF10173.9 KXH51553.1 - 0.012 15.7 0.2 0.61 10.1 0.0 2.9 2 1 0 2 2 2 0 Mitochondrial K+-H+ exchange-related DUF4017 PF13209.6 KXH51553.1 - 0.099 12.6 0.1 0.23 11.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4017) Ank_2 PF12796.7 KXH51554.1 - 1.1e-47 160.5 0.2 8.1e-13 48.8 0.0 6.9 4 2 3 7 7 7 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXH51554.1 - 4e-45 151.6 1.0 3.1e-09 37.2 0.0 10.8 8 3 4 12 12 12 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXH51554.1 - 4.2e-31 103.5 0.3 0.0022 18.3 0.0 12.4 14 0 0 14 14 14 5 Ankyrin repeat Ank_5 PF13857.6 KXH51554.1 - 1e-29 102.2 0.1 1.1e-07 32.0 0.0 7.4 4 2 2 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 KXH51554.1 - 1.4e-29 101.2 0.6 2.3e-05 24.6 0.0 8.9 10 0 0 10 10 10 6 Ankyrin repeat PNP_UDP_1 PF01048.20 KXH51554.1 - 4.9e-06 26.0 0.0 1.4e-05 24.5 0.0 1.8 1 1 0 1 1 1 1 Phosphorylase superfamily NACHT PF05729.12 KXH51554.1 - 5.5e-05 23.2 0.0 0.00013 21.9 0.0 1.6 1 0 0 1 1 1 1 NACHT domain KAP_NTPase PF07693.14 KXH51554.1 - 0.06 12.6 0.7 0.82 8.8 0.2 2.1 1 1 1 2 2 2 0 KAP family P-loop domain AAA_16 PF13191.6 KXH51554.1 - 0.11 12.9 0.0 0.6 10.5 0.0 2.4 1 0 0 1 1 1 0 AAA ATPase domain Ribonuc_L-PSP PF01042.21 KXH51555.1 - 9.6e-37 125.7 0.0 1.1e-36 125.5 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP RRM_1 PF00076.22 KXH51556.1 - 5.2e-11 42.2 0.0 9.2e-11 41.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KXH51556.1 - 3.3e-05 23.5 0.0 7.2e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KXH51556.1 - 0.057 13.5 1.0 0.095 12.8 0.1 1.8 2 0 0 2 2 2 0 RNA binding motif RRM_occluded PF16842.5 KXH51556.1 - 0.093 12.6 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Occluded RNA-recognition motif RF-1 PF00472.20 KXH51557.1 - 1.5e-13 50.7 3.1 2.4e-13 50.1 3.1 1.2 1 0 0 1 1 1 1 RF-1 domain VIT1 PF01988.19 KXH51557.1 - 0.57 10.0 2.1 0.78 9.6 2.1 1.1 1 0 0 1 1 1 0 VIT family Pkinase PF00069.25 KXH51558.1 - 6.5e-69 232.2 0.0 1.6e-68 231.0 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXH51558.1 - 1.2e-26 93.5 0.0 7.3e-26 91.0 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXH51558.1 - 2.4e-07 30.4 0.0 3.3e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KXH51558.1 - 0.00013 20.9 0.0 0.00025 20.0 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KXH51558.1 - 0.00057 19.9 0.0 0.00088 19.3 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KXH51558.1 - 0.00067 19.1 0.0 0.0013 18.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Fungal_trans_2 PF11951.8 KXH51559.1 - 4e-05 22.6 0.2 5.7e-05 22.1 0.2 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain MHYT PF03707.16 KXH51559.1 - 0.027 14.6 0.0 0.068 13.4 0.0 1.6 1 0 0 1 1 1 0 Bacterial signalling protein N terminal repeat PQQ_3 PF13570.6 KXH51560.1 - 0.018 15.6 0.5 0.018 15.6 0.5 5.0 6 1 0 6 6 6 0 PQQ-like domain PQQ_2 PF13360.6 KXH51560.1 - 0.036 13.6 0.7 1.5 8.4 0.2 2.5 2 0 0 2 2 2 0 PQQ-like domain Aim19 PF10315.9 KXH51560.1 - 0.2 12.0 2.4 0.34 11.2 0.4 2.4 3 0 0 3 3 3 0 Altered inheritance of mitochondria protein 19 CLN3 PF02487.17 KXH51562.1 - 5e-39 134.5 0.5 1.6e-38 132.9 0.5 1.6 1 1 0 1 1 1 1 CLN3 protein AOX PF01786.17 KXH51564.1 - 0.16 11.5 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 Alternative oxidase DASH_Spc34 PF08657.10 KXH51568.1 - 8.8e-51 173.1 0.0 1.4e-25 90.6 0.0 2.0 1 1 1 2 2 2 2 DASH complex subunit Spc34 CAP_N PF01213.19 KXH51568.1 - 0.011 15.3 0.5 0.019 14.5 0.5 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal SlyX PF04102.12 KXH51568.1 - 0.13 12.9 6.6 0.64 10.7 0.3 2.8 1 1 1 2 2 2 0 SlyX DUF2968 PF11180.8 KXH51568.1 - 0.15 11.7 7.1 0.24 11.0 7.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) Merozoite_SPAM PF07133.11 KXH51568.1 - 0.57 10.2 12.6 0.86 9.6 12.6 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) VIR_N PF15912.5 KXH51568.1 - 5.4 6.5 14.0 5.1 6.6 2.8 2.1 2 0 0 2 2 2 0 Virilizer, N-terminal Fungal_trans PF04082.18 KXH51594.1 - 4.2e-14 52.2 0.8 6.3e-14 51.6 0.8 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH51594.1 - 6.7e-09 35.7 8.4 1.2e-08 34.9 8.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_3 PF01494.19 KXH51595.1 - 3.2e-21 76.0 0.0 4.4e-21 75.5 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KXH51595.1 - 3e-06 27.1 0.3 0.071 12.7 0.4 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXH51595.1 - 7.4e-05 22.1 0.0 0.12 11.5 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXH51595.1 - 0.0019 18.7 0.4 0.013 16.1 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXH51595.1 - 0.051 13.8 0.1 0.16 12.2 0.1 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain ApbA PF02558.16 KXH51595.1 - 0.14 11.8 0.1 0.3 10.7 0.1 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Acetyltransf_18 PF18014.1 KXH51596.1 - 0.099 12.5 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Homeobox_KN PF05920.11 KXH51597.1 - 1.8e-17 63.0 1.1 9.2e-17 60.7 0.6 2.4 2 0 0 2 2 2 1 Homeobox KN domain HTH_Tnp_Tc5 PF03221.16 KXH51597.1 - 4.4e-05 23.4 0.6 0.033 14.2 0.1 3.7 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain Homeodomain PF00046.29 KXH51597.1 - 5.9e-05 22.8 0.1 0.00014 21.6 0.1 1.6 1 0 0 1 1 1 1 Homeodomain zf-C2H2_4 PF13894.6 KXH51597.1 - 0.002 18.8 3.5 0.002 18.8 3.5 5.4 5 0 0 5 5 5 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KXH51597.1 - 0.014 15.8 23.9 0.019 15.4 3.9 4.4 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-met PF12874.7 KXH51597.1 - 6.1 7.4 10.7 16 6.1 0.3 4.4 5 0 0 5 5 5 0 Zinc-finger of C2H2 type MFS_1 PF07690.16 KXH51598.1 - 5.5e-23 81.5 46.0 7.2e-23 81.1 45.5 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Methyltransf_2 PF00891.18 KXH51601.1 - 1.2e-24 86.8 0.0 1.6e-24 86.3 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain DUF3662 PF12401.8 KXH51601.1 - 0.03 14.7 0.0 0.053 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2662) Abhydrolase_6 PF12697.7 KXH51602.1 - 0.00016 22.4 1.3 0.00016 22.4 1.3 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXH51602.1 - 0.018 14.7 0.1 0.055 13.1 0.0 1.9 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF1749 PF08538.10 KXH51602.1 - 0.059 12.5 0.0 0.089 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) SNARE_assoc PF09335.11 KXH51606.1 - 2.7e-20 73.0 8.4 1.8e-19 70.4 7.5 2.3 2 0 0 2 2 2 1 SNARE associated Golgi protein DUF2142 PF09913.9 KXH51606.1 - 0.0019 17.1 0.8 0.0027 16.7 0.1 1.6 2 0 0 2 2 2 1 Predicted membrane protein (DUF2142) Phage_holin_3_6 PF07332.11 KXH51606.1 - 0.019 15.0 9.8 0.32 11.1 2.2 2.8 2 2 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III SIT PF15330.6 KXH51606.1 - 0.049 14.1 0.5 0.12 12.8 0.1 1.8 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT DUF5305 PF17231.2 KXH51606.1 - 0.08 12.3 0.3 0.87 8.9 0.3 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5305) DUF3671 PF12420.8 KXH51606.1 - 0.11 12.6 4.2 5.7 7.1 1.8 2.3 2 0 0 2 2 2 0 Protein of unknown function Cytadhesin_P30 PF07271.11 KXH51606.1 - 0.14 11.7 0.1 0.26 10.8 0.1 1.5 1 0 0 1 1 1 0 Cytadhesin P30/P32 ESSS PF10183.9 KXH51606.1 - 0.47 10.7 1.7 1.2 9.4 0.0 2.5 3 0 0 3 3 3 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF4519 PF15012.6 KXH51606.1 - 0.92 9.7 4.2 0.96 9.7 0.1 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) SieB PF14163.6 KXH51606.1 - 1.3 8.5 13.4 1.7 8.2 0.3 3.4 1 1 2 4 4 4 0 Super-infection exclusion protein B AhpC-TSA_2 PF13911.6 KXH51607.1 - 3.8e-17 62.4 0.0 1.2e-16 60.8 0.0 1.8 2 0 0 2 2 2 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 KXH51607.1 - 0.012 15.5 0.0 0.04 13.8 0.0 1.8 1 1 0 1 1 1 0 AhpC/TSA family IBR PF01485.21 KXH51609.1 - 6.3e-07 29.5 9.8 0.00015 21.9 0.7 3.6 4 0 0 4 4 4 2 IBR domain, a half RING-finger domain Peptidase_M24 PF00557.24 KXH51611.1 - 1.1e-44 152.7 0.1 1.4e-44 152.3 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Ribosomal_60s PF00428.19 KXH51611.1 - 0.35 11.5 5.6 1.1 9.9 5.6 1.9 1 0 0 1 1 1 0 60s Acidic ribosomal protein SPT6_acidic PF14632.6 KXH51611.1 - 0.9 10.2 7.5 0.071 13.7 1.4 2.0 2 0 0 2 2 2 0 Acidic N-terminal SPT6 PRELI PF04707.14 KXH51612.1 - 4.7e-39 133.7 0.0 5.6e-39 133.5 0.0 1.1 1 0 0 1 1 1 1 PRELI-like family PRK PF00485.18 KXH51614.1 - 2.9e-05 23.9 0.0 9.3e-05 22.2 0.0 1.7 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family NB-ARC PF00931.22 KXH51614.1 - 3.2e-05 23.2 0.0 4.5e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA_18 PF13238.6 KXH51614.1 - 6e-05 23.6 0.1 0.00041 20.9 0.1 2.1 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KXH51614.1 - 0.0019 17.5 0.1 0.0038 16.5 0.0 1.5 2 0 0 2 2 2 1 Zeta toxin Thymidylate_kin PF02223.17 KXH51614.1 - 0.0025 17.5 0.1 0.092 12.4 0.0 2.2 2 0 0 2 2 2 1 Thymidylate kinase RuvB_N PF05496.12 KXH51614.1 - 0.0044 16.8 0.0 0.0072 16.1 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain T2SSE PF00437.20 KXH51614.1 - 0.0061 15.7 0.0 0.052 12.6 0.0 2.0 2 0 0 2 2 2 1 Type II/IV secretion system protein SKI PF01202.22 KXH51614.1 - 0.0097 16.0 0.0 0.2 11.8 0.0 2.3 2 0 0 2 2 2 1 Shikimate kinase AAA_33 PF13671.6 KXH51614.1 - 0.011 15.9 0.1 0.079 13.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 KXH51614.1 - 0.017 15.6 0.1 0.33 11.4 0.0 2.4 2 1 0 2 2 2 0 AAA domain MeaB PF03308.16 KXH51614.1 - 0.017 14.1 0.0 0.026 13.5 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA PF00004.29 KXH51614.1 - 0.018 15.4 0.0 0.03 14.7 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KXH51614.1 - 0.024 14.9 0.0 0.04 14.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KXH51614.1 - 0.041 14.3 0.0 0.054 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Viral_helicase1 PF01443.18 KXH51614.1 - 0.11 12.2 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 KXH51614.1 - 0.14 11.8 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KXH51614.1 - 0.19 11.8 0.0 0.3 11.1 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Tubulin PF00091.25 KXH51617.1 - 3.1e-67 226.6 0.0 4.7e-67 226.0 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KXH51617.1 - 8.2e-46 155.3 0.3 1.5e-45 154.4 0.0 1.6 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 KXH51617.1 - 1.7e-07 31.5 0.0 3.5e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain PLDc PF00614.22 KXH51618.1 - 1.9e-16 59.4 0.4 1.5e-07 31.3 0.2 2.8 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 KXH51618.1 - 8.3e-13 48.4 0.0 8.6e-07 28.9 0.0 2.6 2 0 0 2 2 2 2 PLD-like domain PX PF00787.24 KXH51618.1 - 1.3e-06 28.4 0.2 1.9e-05 24.6 0.0 2.9 3 1 0 3 3 3 1 PX domain DUF4028 PF13220.6 KXH51618.1 - 0.018 14.8 0.1 2.7 7.8 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4028) PH_2 PF08458.10 KXH51618.1 - 0.042 14.2 0.8 0.086 13.2 0.8 1.5 1 0 0 1 1 1 0 Plant pleckstrin homology-like region COQ7 PF03232.13 KXH51619.1 - 3.7e-71 238.4 0.3 4.6e-71 238.1 0.3 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.17 KXH51619.1 - 0.00049 20.5 0.0 0.0014 19.0 0.0 1.7 1 1 0 1 1 1 1 Rubrerythrin Vitellogenin_N PF01347.22 KXH51619.1 - 0.053 11.9 0.0 0.053 11.9 0.0 1.2 1 0 0 1 1 1 0 Lipoprotein amino terminal region Plus-3 PF03126.18 KXH51620.1 - 8.9e-28 97.0 0.0 3.2e-27 95.2 0.0 1.9 1 0 0 1 1 1 1 Plus-3 domain GDPD PF03009.17 KXH51621.1 - 8.7e-33 114.1 0.0 1.4e-32 113.5 0.0 1.3 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.6 KXH51621.1 - 1.7e-05 25.1 1.4 4.7e-05 23.7 1.4 1.8 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Fungal_trans PF04082.18 KXH51622.1 - 1.4e-29 102.9 0.1 1.4e-29 102.9 0.1 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH51622.1 - 7.2e-10 38.8 11.5 1.4e-09 37.9 11.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain bZIP_1 PF00170.21 KXH51622.1 - 0.085 13.0 0.4 0.32 11.1 0.4 2.1 1 0 0 1 1 1 0 bZIP transcription factor Trimer_CC PF08954.11 KXH51622.1 - 0.11 12.1 1.9 0.37 10.4 1.9 2.0 1 0 0 1 1 1 0 Trimerisation motif SET PF00856.28 KXH51623.1 - 0.00061 20.2 0.0 0.0013 19.1 0.0 1.8 1 1 0 1 1 1 1 SET domain TFIIA PF03153.13 KXH51624.1 - 0.016 15.2 19.2 0.046 13.7 14.7 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Pkinase PF00069.25 KXH51625.1 - 1.2e-10 41.2 0.0 2.2e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain HEAT PF02985.22 KXH51625.1 - 1.5e-09 37.3 0.1 0.034 14.4 0.0 5.0 4 0 0 4 4 4 3 HEAT repeat HEAT_2 PF13646.6 KXH51625.1 - 1.2e-05 25.6 0.2 0.01 16.2 0.0 3.4 2 1 2 4 4 4 2 HEAT repeats Pkinase_Tyr PF07714.17 KXH51625.1 - 2.8e-05 23.5 0.0 5e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Cnd1 PF12717.7 KXH51625.1 - 3e-05 24.1 0.0 0.00011 22.3 0.0 1.7 1 1 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 KXH51625.1 - 0.0019 18.7 0.2 5.1 7.7 0.0 3.6 3 1 1 4 4 4 2 HEAT-like repeat WD40 PF00400.32 KXH51626.1 - 3.2e-32 110.1 22.4 4e-09 37.0 0.0 9.2 9 0 0 9 9 9 5 WD domain, G-beta repeat ABC_tran PF00005.27 KXH51626.1 - 6e-32 111.0 0.0 6.8e-23 81.7 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KXH51626.1 - 1.1e-15 58.0 3.7 1.1e-15 58.0 3.7 2.6 3 0 0 3 3 3 1 ABC transporter transmembrane region ANAPC4_WD40 PF12894.7 KXH51626.1 - 8.2e-11 42.1 0.5 0.083 13.2 0.0 5.0 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KXH51626.1 - 5.8e-05 22.2 0.1 1.5 7.7 0.0 4.1 1 1 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PALB2_WD40 PF16756.5 KXH51626.1 - 0.00041 19.4 0.1 0.00041 19.4 0.1 2.0 3 0 0 3 3 3 1 Partner and localizer of BRCA2 WD40 domain AAA_PrkA PF08298.11 KXH51626.1 - 0.00044 19.3 0.0 0.00067 18.7 0.0 1.2 1 0 0 1 1 1 1 PrkA AAA domain DUF87 PF01935.17 KXH51626.1 - 0.00056 20.1 0.3 0.001 19.2 0.3 1.4 1 0 0 1 1 1 1 Helicase HerA, central domain Frtz PF11768.8 KXH51626.1 - 0.0056 15.1 0.0 0.01 14.2 0.0 1.4 1 0 0 1 1 1 1 WD repeat-containing and planar cell polarity effector protein Fritz Nup160 PF11715.8 KXH51626.1 - 0.0067 15.1 2.2 0.54 8.8 0.1 3.6 3 1 0 3 3 3 1 Nucleoporin Nup120/160 Coatomer_WDAD PF04053.14 KXH51626.1 - 0.021 13.9 0.0 0.034 13.2 0.0 1.2 1 0 0 1 1 1 0 Coatomer WD associated region HPS3_N PF14761.6 KXH51626.1 - 0.044 13.3 0.0 0.22 11.0 0.0 2.0 2 0 0 2 2 2 0 Hermansky-Pudlak syndrome 3 AAA_16 PF13191.6 KXH51626.1 - 0.05 14.0 0.1 0.21 11.9 0.0 2.1 2 0 0 2 2 1 0 AAA ATPase domain AAA_22 PF13401.6 KXH51626.1 - 0.055 13.7 0.0 0.16 12.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KXH51626.1 - 0.059 13.1 0.3 0.15 11.8 0.3 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain NTPase_1 PF03266.15 KXH51626.1 - 0.4 10.6 0.9 7.1 6.5 0.1 2.5 2 0 0 2 2 2 0 NTPase DUF3328 PF11807.8 KXH51627.1 - 1.1e-21 77.6 0.0 1.6e-21 77.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) AAA PF00004.29 KXH51637.1 - 1.9e-98 326.0 0.0 9.7e-48 161.9 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KXH51637.1 - 1.5e-25 88.7 6.0 5.2e-14 51.8 0.3 3.6 2 1 1 3 3 3 2 AAA+ lid domain CDC48_N PF02359.18 KXH51637.1 - 5.2e-19 68.2 0.3 2e-18 66.3 0.3 2.1 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 KXH51637.1 - 4.1e-14 52.6 1.2 6e-06 26.1 0.0 3.6 4 2 0 4 4 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 KXH51637.1 - 8.5e-14 52.0 0.0 3.1e-07 30.7 0.0 2.9 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KXH51637.1 - 3.6e-13 50.3 0.0 0.00031 21.2 0.0 4.3 2 2 0 2 2 2 2 AAA ATPase domain AAA_5 PF07728.14 KXH51637.1 - 3.6e-12 46.5 0.3 3.5e-06 27.0 0.1 3.7 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KXH51637.1 - 5.4e-12 46.1 0.0 4.2e-05 23.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 KXH51637.1 - 2.5e-09 37.5 0.5 0.029 14.7 0.1 3.9 2 2 1 3 3 2 2 AAA domain TIP49 PF06068.13 KXH51637.1 - 3.5e-09 36.3 0.0 0.0013 18.1 0.0 2.7 2 0 0 2 2 2 2 TIP49 P-loop domain CDC48_2 PF02933.17 KXH51637.1 - 5.6e-08 32.5 0.0 1.4e-07 31.2 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_18 PF13238.6 KXH51637.1 - 1.7e-07 31.9 0.0 0.028 15.0 0.0 2.9 3 0 0 3 3 2 2 AAA domain Mg_chelatase PF01078.21 KXH51637.1 - 2.2e-07 30.5 0.2 0.0069 15.8 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 KXH51637.1 - 3.5e-07 30.1 0.0 0.019 14.7 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_14 PF13173.6 KXH51637.1 - 4.8e-07 29.9 0.0 0.0076 16.3 0.0 2.9 3 0 0 3 3 2 2 AAA domain RNA_helicase PF00910.22 KXH51637.1 - 6.5e-07 29.7 0.0 0.035 14.5 0.0 2.9 3 0 0 3 3 2 2 RNA helicase ATPase PF06745.13 KXH51637.1 - 1e-06 28.3 0.3 0.25 10.6 0.0 3.6 3 0 0 3 3 3 2 KaiC AAA_25 PF13481.6 KXH51637.1 - 1.2e-06 28.2 3.5 0.2 11.2 0.0 4.5 3 2 2 5 5 5 2 AAA domain AAA_7 PF12775.7 KXH51637.1 - 2.1e-06 27.4 0.1 0.032 13.7 0.0 2.9 2 2 0 2 2 2 2 P-loop containing dynein motor region Vps4_C PF09336.10 KXH51637.1 - 2.8e-06 27.2 0.1 3.4e-05 23.8 0.0 2.5 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_24 PF13479.6 KXH51637.1 - 4.2e-06 26.6 0.0 0.082 12.6 0.0 2.8 3 0 0 3 3 2 2 AAA domain DUF815 PF05673.13 KXH51637.1 - 4.2e-06 26.1 0.0 0.012 14.7 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF815) Parvo_NS1 PF01057.17 KXH51637.1 - 8.8e-06 25.0 0.1 0.052 12.6 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_28 PF13521.6 KXH51637.1 - 1.5e-05 25.3 0.1 0.15 12.3 0.0 2.8 3 0 0 3 3 2 2 AAA domain Sigma54_activat PF00158.26 KXH51637.1 - 2.2e-05 24.2 0.0 0.25 11.0 0.0 3.3 2 2 0 2 2 2 2 Sigma-54 interaction domain ABC_tran PF00005.27 KXH51637.1 - 2.9e-05 24.6 0.0 0.28 11.7 0.0 3.5 2 1 0 2 2 2 2 ABC transporter TsaE PF02367.17 KXH51637.1 - 7.9e-05 22.7 0.0 0.44 10.5 0.0 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Bac_DnaA PF00308.18 KXH51637.1 - 9e-05 22.4 0.0 0.38 10.5 0.0 3.0 3 0 0 3 3 3 2 Bacterial dnaA protein NACHT PF05729.12 KXH51637.1 - 0.00014 21.9 0.1 0.18 11.7 0.0 2.9 3 0 0 3 3 3 1 NACHT domain AAA_11 PF13086.6 KXH51637.1 - 0.00015 21.6 0.1 1 9.1 0.0 3.0 3 0 0 3 3 3 2 AAA domain ResIII PF04851.15 KXH51637.1 - 0.00015 21.8 0.0 0.046 13.7 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_17 PF13207.6 KXH51637.1 - 0.00021 21.7 0.7 0.59 10.6 0.0 3.3 4 0 0 4 4 2 1 AAA domain AAA_3 PF07726.11 KXH51637.1 - 0.00023 21.0 0.0 0.7 9.8 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 KXH51637.1 - 0.00023 20.7 0.3 0.68 9.3 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein AAA_30 PF13604.6 KXH51637.1 - 0.00047 19.9 0.3 1.1 8.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain ATPase_2 PF01637.18 KXH51637.1 - 0.00055 19.9 0.0 2.1 8.2 0.0 3.6 3 1 0 3 3 3 1 ATPase domain predominantly from Archaea AAA_19 PF13245.6 KXH51637.1 - 0.00085 19.7 0.2 5.5 7.3 0.0 3.7 3 1 1 4 4 3 0 AAA domain DUF2075 PF09848.9 KXH51637.1 - 0.002 17.4 0.0 1.7 7.8 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) Sigma54_activ_2 PF14532.6 KXH51637.1 - 0.0036 17.4 0.0 0.55 10.3 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain NB-ARC PF00931.22 KXH51637.1 - 0.0043 16.3 0.0 1.5 8.0 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain NTPase_1 PF03266.15 KXH51637.1 - 0.006 16.5 0.5 2.5 8.0 0.0 3.8 4 0 0 4 4 3 1 NTPase Viral_helicase1 PF01443.18 KXH51637.1 - 0.0075 16.0 0.0 0.33 10.7 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase IPT PF01745.16 KXH51637.1 - 0.013 14.9 0.0 1.8 7.9 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase KAP_NTPase PF07693.14 KXH51637.1 - 0.022 14.0 0.4 1.1 8.4 0.0 3.2 2 2 1 4 4 4 0 KAP family P-loop domain Zeta_toxin PF06414.12 KXH51637.1 - 0.024 13.9 0.6 7.9 5.7 0.0 2.9 3 0 0 3 3 3 0 Zeta toxin UFD1 PF03152.14 KXH51637.1 - 0.03 13.8 0.0 0.17 11.4 0.0 2.0 1 1 1 2 2 2 0 Ubiquitin fusion degradation protein UFD1 AAA_6 PF12774.7 KXH51637.1 - 0.05 12.6 0.1 7.6 5.4 0.0 2.4 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region Cytidylate_kin2 PF13189.6 KXH51637.1 - 0.056 13.6 0.0 3.2 7.8 0.0 2.5 2 0 0 2 2 2 0 Cytidylate kinase-like family Cytidylate_kin PF02224.18 KXH51637.1 - 0.06 13.1 0.0 10 5.8 0.0 2.7 2 0 0 2 2 2 0 Cytidylate kinase Zot PF05707.12 KXH51637.1 - 0.074 12.7 0.0 3 7.5 0.0 2.9 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) AFG1_ATPase PF03969.16 KXH51637.1 - 0.097 11.5 0.0 12 4.7 0.0 2.3 2 0 0 2 2 2 0 AFG1-like ATPase YjeF_N PF03853.15 KXH51640.1 - 5.1e-42 143.6 0.6 2.5e-41 141.4 0.1 2.0 2 0 0 2 2 2 1 YjeF-related protein N-terminus FDF PF09532.10 KXH51640.1 - 2e-07 31.8 0.8 2e-07 31.8 0.8 2.3 2 1 0 2 2 2 1 FDF domain PIF1 PF05970.14 KXH51641.1 - 2.4e-58 198.1 0.2 1.2e-44 153.0 0.1 2.3 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 KXH51641.1 - 6.2e-21 75.0 0.0 1e-20 74.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KXH51641.1 - 1.6e-10 41.5 0.0 3.2e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KXH51641.1 - 1.1e-06 29.0 0.0 3.6e-06 27.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KXH51641.1 - 8.4e-06 26.2 0.5 4e-05 24.1 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 KXH51641.1 - 3.1e-05 23.6 0.0 5.7e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_16 PF13191.6 KXH51641.1 - 0.00022 21.6 0.1 0.00068 20.1 0.0 1.9 2 0 0 2 2 1 1 AAA ATPase domain Herpes_Helicase PF02689.14 KXH51641.1 - 0.00036 18.6 0.1 0.0027 15.7 0.0 1.9 2 0 0 2 2 2 1 Helicase UvrD_C_2 PF13538.6 KXH51641.1 - 0.00037 20.3 0.0 0.0011 18.8 0.0 1.9 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_5 PF07728.14 KXH51641.1 - 0.00068 19.6 0.2 0.0032 17.5 0.1 2.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) PhoH PF02562.16 KXH51641.1 - 0.0038 16.7 0.0 0.0089 15.5 0.0 1.6 1 0 0 1 1 1 1 PhoH-like protein DUF5605 PF18310.1 KXH51641.1 - 0.0044 16.9 0.0 2.3 8.2 0.0 3.3 3 0 0 3 3 3 1 Domain of unknown function (DUF5605) AFG1_ATPase PF03969.16 KXH51641.1 - 0.0061 15.5 0.1 0.014 14.4 0.1 1.5 1 0 0 1 1 1 1 AFG1-like ATPase NB-ARC PF00931.22 KXH51641.1 - 0.0068 15.6 0.1 0.013 14.7 0.1 1.4 1 0 0 1 1 1 1 NB-ARC domain ABC_tran PF00005.27 KXH51641.1 - 0.0086 16.6 3.4 0.013 16.0 0.1 2.6 1 1 1 2 2 2 1 ABC transporter RNA_helicase PF00910.22 KXH51641.1 - 0.011 16.1 0.0 0.033 14.6 0.0 1.8 1 0 0 1 1 1 0 RNA helicase T2SSE PF00437.20 KXH51641.1 - 0.017 14.2 0.0 0.03 13.4 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein TEX33 PF15400.6 KXH51641.1 - 0.019 15.5 0.5 0.054 14.0 0.5 1.8 1 0 0 1 1 1 0 Testis-expressed sequence 33 protein family SH3_13 PF18335.1 KXH51641.1 - 0.021 14.6 0.2 0.096 12.5 0.1 2.2 2 0 0 2 2 1 0 ATP-dependent RecD-like DNA helicase SH3 domain NACHT PF05729.12 KXH51641.1 - 0.021 14.7 0.0 0.044 13.7 0.0 1.5 1 0 0 1 1 1 0 NACHT domain DUF2075 PF09848.9 KXH51641.1 - 0.036 13.3 0.0 0.087 12.0 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RsgA_GTPase PF03193.16 KXH51641.1 - 0.039 13.9 0.1 0.075 12.9 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase ATP-synt_ab PF00006.25 KXH51641.1 - 0.063 12.9 0.0 0.89 9.2 0.0 2.5 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_29 PF13555.6 KXH51641.1 - 0.068 12.9 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATPase_2 PF01637.18 KXH51641.1 - 0.07 13.0 0.5 0.25 11.2 0.0 2.1 3 0 0 3 3 2 0 ATPase domain predominantly from Archaea AAA_14 PF13173.6 KXH51641.1 - 0.092 12.8 0.0 0.35 10.9 0.0 2.0 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KXH51641.1 - 0.092 12.5 0.4 1.3 8.7 0.0 2.7 2 1 1 3 3 3 0 IstB-like ATP binding protein NTPase_1 PF03266.15 KXH51641.1 - 0.11 12.4 0.0 0.37 10.7 0.0 1.9 1 0 0 1 1 1 0 NTPase TsaE PF02367.17 KXH51641.1 - 0.13 12.3 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_11 PF13086.6 KXH51641.1 - 0.14 11.9 0.0 0.14 11.9 0.0 2.7 2 1 1 3 3 2 0 AAA domain DUF87 PF01935.17 KXH51641.1 - 0.24 11.5 0.5 3.9 7.5 0.0 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain Peptidase_M99 PF17033.5 KXH51642.1 - 0.16 11.3 0.0 0.35 10.3 0.0 1.4 2 0 0 2 2 2 0 Carboxypeptidase controlling helical cell shape catalytic RSRP PF17069.5 KXH51642.1 - 8.8 5.8 35.1 0.022 14.4 24.7 1.9 2 0 0 2 2 2 0 Arginine/Serine-Rich protein 1 Hce2 PF14856.6 KXH51644.1 - 1.6e-17 63.6 0.4 2.9e-17 62.8 0.4 1.5 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor Hce2 PF14856.6 KXH51645.1 - 4.2e-10 39.8 0.7 8.3e-10 38.9 0.7 1.5 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor COesterase PF00135.28 KXH51646.1 - 3.3e-75 253.9 0.0 5.9e-74 249.8 0.0 2.2 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXH51646.1 - 2.4e-07 30.8 0.1 8e-07 29.1 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KXH51646.1 - 0.038 13.5 0.5 0.086 12.3 0.4 1.6 2 0 0 2 2 2 0 Prolyl oligopeptidase family DUF842 PF05811.13 KXH51647.1 - 0.064 12.9 0.3 1.6 8.4 0.0 2.3 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF842) SesA PF17107.5 KXH51647.1 - 0.077 13.2 0.1 0.13 12.4 0.1 1.4 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases CH PF00307.31 KXH51648.1 - 3.9e-13 49.5 0.0 7.5e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain CDC24 PF06395.11 KXH51648.1 - 0.0062 16.8 0.0 0.012 15.8 0.0 1.4 1 0 0 1 1 1 1 CDC24 Calponin CAMSAP_CH PF11971.8 KXH51648.1 - 0.1 12.5 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 CAMSAP CH domain NDUFA12 PF05071.16 KXH51649.1 - 1.1e-09 38.9 0.1 1.1e-09 38.9 0.1 2.0 2 0 0 2 2 2 1 NADH ubiquinone oxidoreductase subunit NDUFA12 cwf21 PF08312.12 KXH51650.1 - 5.9e-17 61.5 11.8 5.9e-17 61.5 11.8 2.1 2 0 0 2 2 2 1 cwf21 domain GvpG PF05120.12 KXH51650.1 - 6.3 6.9 11.5 8.5 6.5 3.4 2.4 1 1 1 2 2 2 0 Gas vesicle protein G D123 PF07065.14 KXH51651.1 - 9.1e-116 386.3 0.0 1.1e-115 386.1 0.0 1.0 1 0 0 1 1 1 1 D123 DUF3716 PF12511.8 KXH51652.1 - 9.2e-17 60.8 9.7 1.4e-16 60.3 9.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) G-alpha PF00503.20 KXH51653.1 - 1.1e-124 416.1 2.5 1.3e-124 415.9 2.5 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KXH51653.1 - 3.1e-15 56.1 1.7 2.8e-10 39.9 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family zf-CHC2 PF01807.20 KXH51653.1 - 8.5e-05 22.3 0.0 0.00036 20.3 0.0 1.9 2 0 0 2 2 2 1 CHC2 zinc finger Gtr1_RagA PF04670.12 KXH51653.1 - 0.0019 17.6 2.9 0.11 11.9 0.0 2.7 2 1 1 3 3 3 2 Gtr1/RagA G protein conserved region AAA_29 PF13555.6 KXH51653.1 - 0.014 15.1 0.0 0.033 13.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Roc PF08477.13 KXH51653.1 - 0.024 14.9 0.2 2.4 8.4 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase MCM PF00493.23 KXH51653.1 - 0.058 12.5 0.1 0.11 11.6 0.1 1.5 1 1 0 1 1 1 0 MCM P-loop domain GTP_EFTU PF00009.27 KXH51653.1 - 0.12 11.9 0.0 1.6 8.2 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain FtsK_SpoIIIE PF01580.18 KXH51653.1 - 0.12 11.7 0.0 0.28 10.5 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family MMR_HSR1 PF01926.23 KXH51653.1 - 0.13 12.3 0.1 8.8 6.5 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF1771 PF08590.10 KXH51654.1 - 6.6e-24 84.1 11.8 6.6e-24 84.1 11.8 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) zf-Tim10_DDP PF02953.15 KXH51654.1 - 3e-17 62.0 4.7 3e-17 62.0 4.7 2.4 1 1 1 2 2 2 1 Tim10/DDP family zinc finger Smr PF01713.21 KXH51654.1 - 2.4e-09 37.4 0.3 9.8e-09 35.5 0.3 2.1 1 0 0 1 1 1 1 Smr domain DUF4175 PF13779.6 KXH51654.1 - 0.08 10.9 20.6 0.29 9.0 3.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4175) Nup188_C PF18378.1 KXH51655.1 - 3.1e-156 519.9 0.0 4.8e-156 519.2 0.0 1.3 1 0 0 1 1 1 1 Nuclear pore protein NUP188 C-terminal domain Nup188 PF10487.9 KXH51655.1 - 3.4e-61 207.3 0.0 2.4e-46 158.2 0.0 2.6 2 1 0 2 2 2 2 Nucleoporin subcomplex protein binding to Pom34 IGPS PF00218.21 KXH51656.1 - 7.8e-96 320.1 0.1 1.2e-95 319.6 0.1 1.3 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase PRAI PF00697.22 KXH51656.1 - 6.9e-52 176.1 0.0 2.1e-46 158.1 0.0 2.5 1 1 1 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase GATase PF00117.28 KXH51656.1 - 1.5e-45 155.3 0.0 4.3e-45 153.8 0.0 1.7 2 0 0 2 2 2 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KXH51656.1 - 0.00018 21.3 0.3 0.0015 18.3 0.3 2.4 1 1 0 1 1 1 1 Peptidase C26 NanE PF04131.14 KXH51656.1 - 0.0037 16.5 0.0 0.93 8.7 0.0 3.2 3 0 0 3 3 3 1 Putative N-acetylmannosamine-6-phosphate epimerase FMN_dh PF01070.18 KXH51656.1 - 0.025 13.6 0.1 0.17 10.9 0.0 2.2 2 0 0 2 2 2 0 FMN-dependent dehydrogenase QRPTase_C PF01729.19 KXH51656.1 - 0.05 13.4 0.6 1.4 8.7 0.1 2.6 2 0 0 2 2 2 0 Quinolinate phosphoribosyl transferase, C-terminal domain BRCT_2 PF16589.5 KXH51657.1 - 0.0019 18.6 0.0 0.0038 17.6 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 KXH51657.1 - 0.0048 17.3 0.1 0.013 15.9 0.1 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain SKG6 PF08693.10 KXH51658.1 - 0.00092 18.6 8.0 0.0015 17.9 8.0 1.3 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Syndecan PF01034.20 KXH51658.1 - 0.011 15.6 0.0 0.019 14.9 0.0 1.3 1 0 0 1 1 1 0 Syndecan domain Herpes_gE PF02480.16 KXH51658.1 - 0.015 14.1 0.0 0.025 13.3 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E EphA2_TM PF14575.6 KXH51658.1 - 0.017 16.0 0.0 0.032 15.1 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4328 PF14219.6 KXH51658.1 - 0.021 14.4 0.0 0.029 13.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) CEND1 PF15677.5 KXH51658.1 - 0.054 14.0 1.2 0.09 13.3 0.2 1.8 2 0 0 2 2 2 0 Cell cycle exit and neuronal differentiation protein 1 Adeno_E3_CR2 PF02439.15 KXH51658.1 - 0.07 12.9 0.5 0.14 12.0 0.5 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Mid2 PF04478.12 KXH51659.1 - 0.17 11.7 0.0 0.28 11.0 0.0 1.3 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor MaoC_dehydratas PF01575.19 KXH51660.1 - 1.1e-05 25.0 0.0 1.7e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 MaoC like domain eRF1_2 PF03464.15 KXH51661.1 - 3.5e-46 156.8 0.0 5.9e-46 156.1 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 KXH51661.1 - 2.1e-40 137.7 0.7 4.1e-40 136.8 0.7 1.5 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 KXH51661.1 - 7.2e-22 77.8 0.0 1.1e-21 77.1 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 baeRF_family10 PF18854.1 KXH51661.1 - 9.8e-11 42.1 0.4 2.7e-10 40.6 0.0 1.8 2 0 0 2 2 2 1 Bacterial archaeo-eukaryotic release factor family 10 acVLRF1 PF18859.1 KXH51661.1 - 8.8e-10 39.0 0.0 1.4e-09 38.3 0.0 1.3 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor DUF1770 PF08589.10 KXH51662.1 - 7.7e-37 126.2 1.3 1e-36 125.8 1.3 1.2 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1770) Nop14 PF04147.12 KXH51663.1 - 0.24 9.6 7.3 0.31 9.2 7.3 1.2 1 0 0 1 1 1 0 Nop14-like family Ribosomal_L2_C PF03947.18 KXH51664.1 - 7.6e-42 142.5 4.9 1.3e-41 141.7 4.9 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 KXH51664.1 - 1.9e-15 56.5 0.1 4.5e-15 55.4 0.1 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain PfkB PF00294.24 KXH51665.1 - 6e-66 222.8 0.1 6.8e-66 222.6 0.1 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 KXH51665.1 - 0.11 11.9 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase EST1_DNA_bind PF10373.9 KXH51666.1 - 6.3e-50 170.2 0.3 6.3e-50 170.2 0.3 1.5 2 0 0 2 2 2 1 Est1 DNA/RNA binding domain EST1 PF10374.9 KXH51666.1 - 3.9e-20 72.9 1.8 5.4e-20 72.4 0.3 2.1 2 0 0 2 2 2 1 Telomerase activating protein Est1 XPA_N PF01286.18 KXH51667.1 - 0.069 13.2 0.4 0.24 11.5 0.4 1.9 1 1 1 2 2 2 0 XPA protein N-terminal SRP9-21 PF05486.12 KXH51667.1 - 0.16 12.4 0.9 0.31 11.4 0.0 1.8 2 0 0 2 2 2 0 Signal recognition particle 9 kDa protein (SRP9) zf-C2H2_11 PF16622.5 KXH51667.1 - 0.34 10.7 2.2 0.72 9.7 2.2 1.5 1 0 0 1 1 1 0 zinc-finger C2H2-type G10 PF01125.17 KXH51668.1 - 1.1e-63 213.4 4.0 1.2e-63 213.2 4.0 1.0 1 0 0 1 1 1 1 G10 protein Complex1_LYR_2 PF13233.6 KXH51669.1 - 2.8e-06 28.0 0.1 3.8e-06 27.5 0.1 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 KXH51669.1 - 0.00052 20.0 0.2 0.0012 18.9 0.2 1.6 1 1 0 1 1 1 1 Complex 1 protein (LYR family) RNA_pol_L_2 PF13656.6 KXH51670.1 - 2.6e-30 104.0 0.0 3.2e-30 103.7 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 KXH51670.1 - 2.1e-11 43.1 0.0 3e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Epimerase PF01370.21 KXH51766.1 - 6.9e-23 81.4 0.0 1.2e-22 80.6 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXH51766.1 - 5.8e-14 52.2 0.0 1e-13 51.5 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KXH51766.1 - 1.3e-12 47.4 0.0 1.8e-12 46.9 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KXH51766.1 - 1.3e-09 37.7 0.0 2.5e-07 30.2 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 KXH51766.1 - 5.2e-07 29.7 0.0 9.6e-07 28.9 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 KXH51766.1 - 8.8e-07 28.3 0.0 1.5e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KXH51766.1 - 5.7e-06 25.7 0.0 3.1e-05 23.3 0.0 2.0 1 1 1 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.10 KXH51766.1 - 0.069 13.1 0.9 3 7.7 0.9 2.3 1 1 0 1 1 1 0 KR domain ILVD_EDD PF00920.21 KXH51767.1 - 3.4e-198 659.5 0.1 3.9e-198 659.3 0.1 1.0 1 0 0 1 1 1 1 Dehydratase family CENP-O PF09496.10 KXH51793.1 - 5.2e-72 242.3 1.5 1.8e-71 240.5 0.0 1.9 2 0 0 2 2 2 1 Cenp-O kinetochore centromere component Phage_GP20 PF06810.11 KXH51793.1 - 0.021 14.6 3.8 0.05 13.4 3.8 1.5 1 0 0 1 1 1 0 Phage minor structural protein GP20 DUF732 PF05305.14 KXH51793.1 - 0.064 13.6 0.1 0.12 12.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF732) Acatn PF13000.7 KXH51794.1 - 1.2e-166 555.5 17.0 7.6e-85 285.5 6.9 3.2 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 DFP PF04127.15 KXH51795.1 - 6.4e-15 55.5 0.0 3e-06 27.2 0.0 3.2 2 1 1 3 3 3 3 DNA / pantothenate metabolism flavoprotein MFS_1 PF07690.16 KXH51796.1 - 2.1e-40 138.7 77.0 2.4e-37 128.7 50.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH51796.1 - 3.5e-10 39.3 44.5 3.1e-06 26.3 20.4 2.4 2 1 0 2 2 2 2 Sugar (and other) transporter Epiglycanin_C PF14654.6 KXH51796.1 - 4.4 7.4 9.4 11 6.1 0.1 3.5 4 0 0 4 4 4 0 Mucin, catalytic, TM and cytoplasmic tail region Clr5 PF14420.6 KXH51800.1 - 8.8e-18 64.3 1.2 2.1e-17 63.1 0.4 2.1 2 0 0 2 2 2 1 Clr5 domain FAD-oxidase_C PF02913.19 KXH51801.1 - 2.2e-63 214.2 0.4 2.2e-63 214.2 0.4 1.7 2 0 0 2 2 2 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KXH51801.1 - 2.6e-37 127.6 0.0 5.6e-37 126.6 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain tRNA-synt_1 PF00133.22 KXH51802.1 - 4.7e-154 513.9 0.0 7.4e-154 513.3 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KXH51802.1 - 6.2e-18 65.2 0.0 1.3e-17 64.2 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KXH51802.1 - 6.6e-17 61.3 0.0 2.8e-10 39.5 0.0 3.2 3 0 0 3 3 3 3 tRNA synthetases class I (M) zf-FPG_IleRS PF06827.14 KXH51802.1 - 0.014 15.3 6.2 0.039 13.8 6.2 1.9 1 1 0 1 1 1 0 Zinc finger found in FPG and IleRS tRNA-synt_1e PF01406.19 KXH51802.1 - 0.056 12.8 0.0 7 5.9 0.0 2.4 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain PRP9_N PF16958.5 KXH51803.1 - 0.008 16.2 0.7 0.016 15.2 0.7 1.5 1 0 0 1 1 1 1 Pre-mRNA-splicing factor PRP9 N-terminus ECSIT_C PF14784.6 KXH51803.1 - 0.11 12.9 0.0 1.6 9.1 0.0 2.6 2 0 0 2 2 2 0 C-terminal domain of the ECSIT protein Ferlin_C PF16165.5 KXH51803.1 - 6 6.8 7.4 10 6.1 4.0 2.8 2 1 1 3 3 3 0 Ferlin C-terminus CBP_BcsF PF11120.8 KXH51804.1 - 1.3 9.2 3.6 0.47 10.6 0.7 1.7 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsF Tom37 PF10568.9 KXH51805.1 - 2.9e-34 118.1 0.3 4.4e-34 117.5 0.3 1.3 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_6 PF17171.4 KXH51805.1 - 7.8e-08 32.0 1.3 3.7e-07 29.9 0.0 2.8 3 1 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 KXH51805.1 - 1.1e-07 32.5 0.0 2.2e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_2 PF13410.6 KXH51805.1 - 0.00036 20.5 0.1 0.0014 18.6 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain PIG-U PF06728.13 KXH51806.1 - 6.5e-125 417.1 24.4 7.5e-125 416.9 24.4 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U Mannosyl_trans PF05007.13 KXH51806.1 - 0.00023 21.1 1.4 0.00033 20.6 0.1 1.7 1 1 0 2 2 2 1 Mannosyltransferase (PIG-M) 8TM_micro PF17028.5 KXH51806.1 - 0.23 11.2 7.6 0.99 9.1 7.6 1.9 1 1 0 1 1 1 0 8TM Microsporidial transmembrane domain Pescadillo_N PF06732.11 KXH51807.1 - 5.2e-122 406.6 0.0 5.2e-122 406.6 0.0 1.6 2 0 0 2 2 2 1 Pescadillo N-terminus Astro_capsid_p PF12226.8 KXH51807.1 - 0.001 18.3 7.4 0.001 18.3 7.4 2.3 2 0 0 2 2 2 1 Turkey astrovirus capsid protein BRCT_2 PF16589.5 KXH51807.1 - 0.0011 19.3 0.2 0.0089 16.4 0.0 2.6 2 2 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain RRN9 PF10680.9 KXH51808.1 - 7.8e-17 61.3 0.1 7.8e-17 61.3 0.1 3.0 3 0 0 3 3 3 1 RNA polymerase I specific transcription initiation factor Aldedh PF00171.22 KXH51809.1 - 3e-165 550.2 1.0 3.7e-165 549.9 1.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Glyco_hydro_79C PF16862.5 KXH51810.1 - 5.2e-24 85.1 1.2 1.1e-23 84.1 0.4 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase family 79 C-terminal beta domain DUF3336 PF11815.8 KXH51823.1 - 3.6e-53 179.0 1.0 5.7e-53 178.3 1.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 KXH51823.1 - 1.9e-19 70.6 0.5 1.6e-18 67.7 0.0 2.6 3 1 0 3 3 3 1 Patatin-like phospholipase Acyltransferase PF01553.21 KXH51824.1 - 8.1e-33 112.9 0.0 1.4e-32 112.2 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Lip_A_acyltrans PF03279.13 KXH51824.1 - 0.022 13.9 0.0 0.028 13.6 0.0 1.2 1 0 0 1 1 1 0 Bacterial lipid A biosynthesis acyltransferase Ribonuc_L-PSP PF01042.21 KXH51824.1 - 0.04 13.9 0.0 0.13 12.3 0.0 1.7 2 0 0 2 2 2 0 Endoribonuclease L-PSP DUF2347 PF09804.9 KXH51825.1 - 9e-110 366.7 0.0 1.1e-109 366.4 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) DUF4484 PF14831.6 KXH51825.1 - 1.1e-61 208.5 3.8 1.1e-61 208.5 3.8 2.7 2 1 0 2 2 2 1 Domain of unknown function (DUF4484) SPA PF08616.10 KXH51825.1 - 0.00023 21.1 0.0 0.00053 19.9 0.0 1.5 1 1 0 1 1 1 1 Stabilization of polarity axis Importin_rep_4 PF18808.1 KXH51825.1 - 0.015 15.5 1.8 0.023 15.0 0.8 1.8 2 0 0 2 2 2 0 Importin repeat Pro-kuma_activ PF09286.11 KXH51842.1 - 3.9e-49 166.6 0.3 1.1e-48 165.1 0.3 1.8 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Complex1_LYR PF05347.15 KXH51842.1 - 2.1e-17 62.9 2.4 5.8e-17 61.5 2.4 1.7 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KXH51842.1 - 5.3e-05 23.9 1.2 5.3e-05 23.9 1.2 1.8 2 0 0 2 2 2 1 Complex1_LYR-like Peptidase_S8 PF00082.22 KXH51842.1 - 0.00011 21.5 2.2 0.00019 20.8 2.2 1.3 1 0 0 1 1 1 1 Subtilase family HTH_Crp_2 PF13545.6 KXH51842.1 - 0.098 12.6 0.0 0.26 11.3 0.0 1.6 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain WD40 PF00400.32 KXH51843.1 - 4.4e-12 46.3 3.7 0.0032 18.3 0.1 4.8 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXH51843.1 - 0.025 14.8 0.1 6.2 7.2 0.0 3.5 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 KXH51843.1 - 0.05 14.1 0.0 5.3 7.7 0.0 3.5 3 0 0 3 3 3 0 PQQ-like domain Ank_4 PF13637.6 KXH51845.1 - 1.4e-06 28.7 0.4 0.00072 20.1 0.1 3.1 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXH51845.1 - 4.8e-06 26.5 0.3 0.0044 17.4 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 KXH51845.1 - 9.5e-06 25.8 2.2 0.019 15.4 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 KXH51845.1 - 7.1e-05 23.0 0.7 0.073 13.4 0.0 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXH51845.1 - 9e-05 23.0 0.0 0.034 14.7 0.0 2.7 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) adh_short PF00106.25 KXH51847.1 - 0.00078 18.9 0.0 0.001 18.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXH51847.1 - 0.0025 17.8 0.0 0.0038 17.2 0.0 1.2 1 0 0 1 1 1 1 KR domain RsgA_GTPase PF03193.16 KXH51847.1 - 0.11 12.3 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase Carb_anhydrase PF00194.21 KXH51850.1 - 9.1e-28 97.5 0.0 5e-13 49.2 0.0 2.1 2 0 0 2 2 2 2 Eukaryotic-type carbonic anhydrase APH PF01636.23 KXH51851.1 - 2.3e-23 83.4 0.1 4.5e-23 82.4 0.1 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KXH51851.1 - 0.0078 15.2 0.0 0.012 14.6 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Choline_kinase PF01633.20 KXH51851.1 - 0.02 14.5 0.0 0.033 13.8 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase SKG6 PF08693.10 KXH51852.1 - 1.2e-06 27.7 2.7 2.8e-06 26.6 2.7 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain BatD PF13584.6 KXH51852.1 - 0.046 12.5 0.0 0.063 12.1 0.0 1.1 1 0 0 1 1 1 0 Oxygen tolerance DUF4381 PF14316.6 KXH51852.1 - 0.12 12.6 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) SCF PF02404.15 KXH51852.1 - 0.14 11.5 0.0 0.28 10.5 0.0 1.5 1 0 0 1 1 1 0 Stem cell factor DUF2207 PF09972.9 KXH51852.1 - 0.15 10.8 0.0 0.23 10.2 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Glyco_hydro_47 PF01532.20 KXH51853.1 - 1.2e-144 482.7 0.0 1.5e-144 482.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 2-Hacid_dh_C PF02826.19 KXH51854.1 - 3.6e-45 153.5 0.0 5.8e-45 152.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KXH51854.1 - 7.4e-05 22.4 0.0 0.0014 18.3 0.0 2.0 1 1 1 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AdoHcyase_NAD PF00670.21 KXH51854.1 - 0.0027 17.8 0.0 0.033 14.3 0.0 2.1 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_7 PF13241.6 KXH51854.1 - 0.018 15.5 0.0 0.064 13.7 0.0 1.9 2 0 0 2 2 2 0 Putative NAD(P)-binding XdhC_C PF13478.6 KXH51854.1 - 0.13 12.8 0.0 0.69 10.4 0.0 2.0 2 0 0 2 2 2 0 XdhC Rossmann domain ADH_N PF08240.12 KXH51890.1 - 9.2e-18 64.1 0.3 1.2e-17 63.8 0.3 1.1 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_assoc PF13823.6 KXH51890.1 - 0.0014 18.5 0.3 0.0039 17.1 0.3 1.9 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-associated MFS_1 PF07690.16 KXH51902.1 - 2.9e-34 118.5 36.6 2.9e-34 118.5 36.6 1.9 2 0 0 2 2 2 2 Major Facilitator Superfamily p450 PF00067.22 KXH51904.1 - 2.3e-78 264.0 0.0 3.1e-78 263.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.20 KXH51904.1 - 4e-29 101.8 0.0 6.8e-29 101.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KXH51904.1 - 1.9e-25 89.7 0.0 5.8e-25 88.2 0.0 1.9 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.21 KXH51904.1 - 4.6e-14 53.0 0.0 1.5e-13 51.3 0.0 2.0 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 KXH51904.1 - 0.00065 20.0 0.0 0.0016 18.7 0.0 1.7 1 0 0 1 1 1 1 Flavodoxin domain FMN_red PF03358.15 KXH51904.1 - 0.057 13.2 0.0 6.6 6.5 0.0 2.4 1 1 1 2 2 2 0 NADPH-dependent FMN reductase DUF4296 PF14129.6 KXH51904.1 - 0.077 13.6 0.1 0.26 11.9 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4296) Abhydrolase_3 PF07859.13 KXH51905.1 - 2.2e-49 168.2 0.0 2.6e-49 167.9 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KXH51905.1 - 0.0025 16.8 0.2 0.012 14.6 0.2 1.8 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 KXH51905.1 - 0.043 13.3 0.0 7.4 6.0 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family AXE1 PF05448.12 KXH51905.1 - 0.25 10.0 0.0 0.39 9.3 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) MFS_1 PF07690.16 KXH51906.1 - 5.7e-18 65.0 45.5 1.7e-13 50.2 30.8 2.7 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.13 KXH51906.1 - 2.5e-05 22.9 5.1 2.5e-05 22.9 5.1 2.4 3 0 0 3 3 3 1 Fungal trichothecene efflux pump (TRI12) Transport_MerF PF11431.8 KXH51906.1 - 0.41 10.6 4.3 14 5.7 0.7 3.1 2 0 0 2 2 2 0 Membrane transport protein MerF Peptidase_C2 PF00648.21 KXH51907.1 - 2e-63 214.2 3.8 2.6e-62 210.5 3.8 2.1 1 1 0 1 1 1 1 Calpain family cysteine protease Peptidase_S10 PF00450.22 KXH51908.1 - 1.8e-85 287.9 0.0 3e-83 280.6 0.0 2.0 1 1 0 1 1 1 1 Serine carboxypeptidase Fungal_trans_2 PF11951.8 KXH51909.1 - 0.0019 17.1 0.1 0.0073 15.2 0.1 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain NAD_binding_10 PF13460.6 KXH51911.1 - 9.5e-08 32.1 0.1 1.6e-07 31.4 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 KXH51911.1 - 8.7e-06 26.2 0.0 2.2e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.21 KXH51911.1 - 9.6e-06 25.2 0.1 0.00086 18.8 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXH51911.1 - 0.00048 19.2 0.0 0.028 13.4 0.0 2.1 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KXH51911.1 - 0.02 14.1 0.0 0.057 12.6 0.0 1.8 2 0 0 2 2 2 0 Male sterility protein NmrA PF05368.13 KXH51911.1 - 0.029 13.9 0.0 0.045 13.3 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family GDP_Man_Dehyd PF16363.5 KXH51911.1 - 0.059 12.8 0.1 1.4 8.2 0.0 2.3 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KXH51911.1 - 0.17 11.0 0.0 0.26 10.4 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Bac_luciferase PF00296.20 KXH51912.1 - 3.5e-74 250.1 0.4 4.3e-74 249.8 0.4 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase NapD PF03927.13 KXH51913.1 - 0.031 14.3 0.1 0.058 13.4 0.1 1.4 1 0 0 1 1 1 0 NapD protein DUF2407_C PF13373.6 KXH51913.1 - 0.75 10.0 3.1 0.78 9.9 0.9 2.1 2 0 0 2 2 2 0 DUF2407 C-terminal domain DUF202 PF02656.15 KXH51913.1 - 9.1 6.8 12.6 0.33 11.4 0.5 3.3 2 1 0 2 2 2 0 Domain of unknown function (DUF202) Bestrophin PF01062.21 KXH51914.1 - 1.3e-35 123.2 0.2 2.2e-35 122.5 0.2 1.2 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel HET PF06985.11 KXH51918.1 - 1.9e-27 96.4 0.0 1.3e-23 83.9 0.0 2.4 2 0 0 2 2 2 2 Heterokaryon incompatibility protein (HET) Flu_M2 PF00599.17 KXH51918.1 - 0.33 11.1 1.0 3.7 7.7 0.1 2.5 2 0 0 2 2 2 0 Influenza Matrix protein (M2) FAD_binding_4 PF01565.23 KXH51919.1 - 5.5e-22 78.0 2.9 9.2e-22 77.3 2.9 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KXH51919.1 - 3.6e-09 36.6 0.0 1e-08 35.1 0.0 1.8 2 0 0 2 2 2 1 Berberine and berberine like adh_short PF00106.25 KXH51920.1 - 3e-22 79.0 0.0 1.4e-21 76.8 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXH51920.1 - 9.4e-13 48.3 0.0 1.9e-12 47.3 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH51920.1 - 1.5e-06 28.2 0.2 2.8e-06 27.3 0.2 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KXH51920.1 - 2.8e-06 27.0 0.0 5.2e-06 26.1 0.0 1.4 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXH51920.1 - 0.00011 21.8 0.0 0.00015 21.3 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Peptidase_S10 PF00450.22 KXH51921.1 - 8.5e-80 269.2 0.2 1.5e-79 268.4 0.2 1.3 1 1 0 1 1 1 1 Serine carboxypeptidase DUF3328 PF11807.8 KXH51922.1 - 1.5e-26 93.5 5.4 1.1e-25 90.7 5.4 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) Acetyltransf_3 PF13302.7 KXH51923.1 - 9e-18 65.3 0.0 1.3e-17 64.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXH51923.1 - 9.5e-09 35.5 0.0 1.6e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Lactonase PF10282.9 KXH51924.1 - 8.1e-77 258.8 0.1 1e-76 258.5 0.1 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller SGL PF08450.12 KXH51925.1 - 0.12 11.9 0.0 7.6 6.0 0.0 2.3 2 0 0 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region Glyco_hydro_88 PF07470.13 KXH51926.1 - 7.1e-35 120.7 0.3 8.3e-35 120.5 0.3 1.1 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 p450 PF00067.22 KXH51928.1 - 1.8e-62 211.6 0.0 2.6e-62 211.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ketoacyl-synt PF00109.26 KXH51929.1 - 1.1e-65 221.8 0.0 2.1e-65 220.8 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain SAT PF16073.5 KXH51929.1 - 1.1e-45 156.2 0.0 1.8e-44 152.3 0.0 2.5 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Acyl_transf_1 PF00698.21 KXH51929.1 - 1e-42 146.8 0.1 2e-42 145.8 0.1 1.5 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KXH51929.1 - 1.5e-37 128.2 0.0 4.8e-37 126.6 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.6 KXH51929.1 - 9e-13 48.1 0.0 1.6e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Thioesterase PF00975.20 KXH51929.1 - 1.2e-12 48.5 0.1 1.9e-11 44.5 0.0 2.4 2 0 0 2 2 2 1 Thioesterase domain PP-binding PF00550.25 KXH51929.1 - 1.2e-12 48.0 0.1 4.7e-12 46.1 0.1 2.0 2 0 0 2 2 2 1 Phosphopantetheine attachment site KAsynt_C_assoc PF16197.5 KXH51929.1 - 7.1e-06 26.4 0.1 1.7e-05 25.2 0.1 1.6 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 KXH51929.1 - 0.084 12.2 0.1 0.19 11.1 0.1 1.5 1 0 0 1 1 1 0 Thiolase, N-terminal domain adh_short_C2 PF13561.6 KXH51930.1 - 2.5e-31 109.0 0.0 2.2e-30 106.0 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXH51930.1 - 2.5e-28 98.9 0.2 1.1e-27 96.8 0.2 1.8 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXH51930.1 - 0.00034 20.6 0.1 0.00064 19.7 0.1 1.4 1 1 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 KXH51930.1 - 0.061 12.6 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF1776 PF08643.10 KXH51930.1 - 0.093 12.1 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) p450 PF00067.22 KXH51931.1 - 3.8e-44 151.2 0.0 4.9e-44 150.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PI_PP_I PF18363.1 KXH51931.1 - 0.029 14.6 1.8 3.8 7.8 0.1 2.4 2 0 0 2 2 2 0 Phosphoinositide phosphatase insertion domain MFS_1 PF07690.16 KXH51932.1 - 3.2e-25 88.8 27.8 4.5e-25 88.3 27.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH51932.1 - 3.5e-05 22.9 1.2 3.5e-05 22.9 1.2 2.8 2 1 1 3 3 3 2 Sugar (and other) transporter MFS_1 PF07690.16 KXH51933.1 - 6.6e-38 130.5 52.7 6.6e-38 130.5 52.7 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KXH51933.1 - 6.5e-11 41.4 16.3 1e-10 40.7 16.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Methyltransf_23 PF13489.6 KXH51934.1 - 1.1e-09 38.4 0.0 1.5e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH51934.1 - 2.2e-07 31.5 0.0 6.2e-07 30.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH51934.1 - 2.6e-06 28.0 0.0 9.1e-06 26.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH51934.1 - 3.8e-06 27.6 0.0 8e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain SnoaL PF07366.12 KXH51935.1 - 3.2e-12 46.4 0.6 5.3e-12 45.6 0.6 1.3 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 KXH51935.1 - 2.1e-05 25.1 0.5 6.2e-05 23.6 0.3 1.8 2 0 0 2 2 2 1 SnoaL-like domain Rad17 PF03215.15 KXH51935.1 - 0.0041 17.1 0.1 0.0085 16.0 0.0 1.5 2 0 0 2 2 2 1 Rad17 P-loop domain ketoacyl-synt PF00109.26 KXH51936.1 - 5.5e-72 242.4 0.0 9.2e-72 241.6 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KXH51936.1 - 8.9e-62 208.2 0.0 3.1e-61 206.4 0.0 2.0 2 0 0 2 2 2 1 KR domain ADH_zinc_N PF00107.26 KXH51936.1 - 1.1e-16 61.0 0.0 4.6e-16 59.0 0.0 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXH51936.1 - 2.9e-16 60.7 0.0 1.2e-15 58.7 0.0 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase adh_short PF00106.25 KXH51936.1 - 1.4e-12 47.5 0.1 4.6e-10 39.3 0.0 3.4 4 0 0 4 4 4 1 short chain dehydrogenase ADH_N PF08240.12 KXH51936.1 - 3.7e-07 30.0 0.1 8.3e-07 28.9 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.25 KXH51936.1 - 8.9e-07 29.2 0.0 2.2e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Ketoacyl-synt_C PF02801.22 KXH51936.1 - 4.3e-06 26.7 0.1 1.5e-05 25.0 0.1 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 KXH51936.1 - 1.2e-05 24.9 0.1 2.3e-05 23.9 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain adh_short PF00106.25 KXH51937.1 - 2.1e-37 128.5 0.3 2.8e-37 128.1 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXH51937.1 - 2e-32 112.6 0.3 2.6e-32 112.3 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH51937.1 - 2e-06 27.9 0.0 3.9e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXH51937.1 - 0.00043 19.8 0.0 0.00057 19.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Methyltransf_25 PF13649.6 KXH51937.1 - 0.004 17.8 0.0 0.011 16.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Polysacc_synt_2 PF02719.15 KXH51937.1 - 0.083 12.0 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Glyco_hydro_1 PF00232.18 KXH51938.1 - 1.3e-74 251.3 0.2 4.1e-74 249.6 0.2 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 1 Cellulase PF00150.18 KXH51938.1 - 0.077 12.4 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) Peptidase_S8 PF00082.22 KXH51939.1 - 5.8e-49 167.0 2.6 8.3e-49 166.4 2.6 1.2 1 0 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 KXH51939.1 - 8.6e-19 68.3 0.0 1.7e-18 67.4 0.0 1.5 1 0 0 1 1 1 1 Fn3-like domain p450 PF00067.22 KXH51940.1 - 2.6e-59 201.2 0.0 3.4e-59 200.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 KorB PF08535.10 KXH51940.1 - 0.11 12.5 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 KorB domain Gpr1_Fun34_YaaH PF01184.19 KXH51941.1 - 2e-89 298.7 17.2 2.5e-89 298.3 17.2 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family FAD_binding_2 PF00890.24 KXH51942.1 - 7.2e-65 219.7 6.2 8.4e-65 219.5 6.2 1.0 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KXH51942.1 - 4.6e-08 33.0 3.9 3.3e-07 30.2 3.9 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXH51942.1 - 1.3e-07 31.8 0.5 3.8e-07 30.2 0.5 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXH51942.1 - 4.4e-07 29.4 2.2 4.4e-06 26.1 0.8 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KXH51942.1 - 7.6e-07 28.7 0.5 1.3e-06 27.9 0.5 1.3 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KXH51942.1 - 8.3e-06 25.4 2.1 1.4e-05 24.6 2.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KXH51942.1 - 2.1e-05 23.4 4.1 0.00053 18.8 0.4 3.0 3 0 0 3 3 3 1 HI0933-like protein AlaDh_PNT_C PF01262.21 KXH51942.1 - 0.00016 21.0 1.7 0.00017 21.0 0.1 1.8 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 KXH51942.1 - 0.00022 20.4 5.0 0.00086 18.5 0.5 2.9 3 0 0 3 3 3 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 KXH51942.1 - 0.00037 19.8 0.0 0.051 12.8 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXH51942.1 - 0.0013 18.0 0.2 0.048 12.9 0.0 2.3 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.27 KXH51942.1 - 0.0049 17.4 0.1 0.023 15.3 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KXH51942.1 - 0.018 14.1 1.3 0.074 12.1 0.3 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein 3HCDH_N PF02737.18 KXH51942.1 - 0.058 13.3 0.1 0.094 12.6 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Peptidase_S8 PF00082.22 KXH51943.1 - 5.6e-34 117.8 14.3 9.9e-34 117.0 14.3 1.4 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 KXH51943.1 - 1.5e-05 25.5 0.0 7.4e-05 23.3 0.0 2.1 1 1 0 1 1 1 1 Peptidase inhibitor I9 NMT1 PF09084.11 KXH51944.1 - 1.5e-79 266.9 0.0 1.9e-79 266.6 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 KXH51944.1 - 5.6e-06 26.2 0.1 0.31 10.7 0.0 3.6 3 1 1 4 4 4 2 NMT1-like family DUF3176 PF11374.8 KXH51945.1 - 1.4 9.1 7.0 1.5 9.0 5.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3176) HET PF06985.11 KXH51946.1 - 1.1e-24 87.5 0.0 2.4e-24 86.4 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ferritin_2 PF13668.6 KXH51947.1 - 0.0001 22.5 0.0 0.00016 21.9 0.0 1.3 1 0 0 1 1 1 1 Ferritin-like domain Peptidase_S41 PF03572.18 KXH51949.1 - 1.3e-05 24.8 0.0 3.9e-05 23.3 0.0 1.8 1 1 0 1 1 1 1 Peptidase family S41 CorA PF01544.18 KXH51950.1 - 5.7e-11 42.3 1.2 1.2e-10 41.2 1.2 1.5 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF676 PF05057.14 KXH51950.1 - 5.2e-06 26.1 0.0 1.1e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 KXH51950.1 - 0.024 13.9 0.0 0.044 13.0 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF2960 PF11173.8 KXH51950.1 - 0.049 14.1 0.0 0.13 12.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2960) Tropomyosin_1 PF12718.7 KXH51950.1 - 0.23 11.6 16.3 0.4 10.8 16.3 1.4 1 0 0 1 1 1 0 Tropomyosin like F_bP_aldolase PF01116.20 KXH51951.1 - 1.1e-72 244.9 0.0 1.2e-72 244.7 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II HET PF06985.11 KXH51952.1 - 2.3e-13 50.7 2.7 3.1e-11 43.8 0.1 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) F-box-like PF12937.7 KXH51964.1 - 0.0098 15.8 0.1 0.23 11.4 0.0 2.6 2 0 0 2 2 2 1 F-box-like Pyrid_ox_like PF16242.5 KXH51965.1 - 2.2e-22 79.2 0.0 3.3e-22 78.7 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase like Putative_PNPOx PF01243.20 KXH51965.1 - 3.7e-08 33.4 0.0 7e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase TP_methylase PF00590.20 KXH51966.1 - 1.5e-22 80.6 0.3 2.5e-22 79.9 0.3 1.4 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases zf-C2H2_jaz PF12171.8 KXH51967.1 - 4.8e-07 29.9 0.1 7.8e-07 29.2 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KXH51967.1 - 4.9e-05 23.6 0.1 8.3e-05 22.8 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type SNRNP27 PF08648.12 KXH51967.1 - 0.00062 19.8 0.7 0.0022 18.0 0.7 2.0 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins zf-DBF PF07535.12 KXH51967.1 - 0.0052 16.9 0.1 0.0099 16.0 0.1 1.4 1 0 0 1 1 1 1 DBF zinc finger DUF1949 PF09186.11 KXH51967.1 - 0.068 13.1 0.6 0.34 10.8 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1949) zf-C2H2 PF00096.26 KXH51967.1 - 0.1 13.1 0.4 0.17 12.4 0.4 1.4 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-U1 PF06220.12 KXH51967.1 - 0.15 11.9 0.1 0.33 10.7 0.1 1.5 1 0 0 1 1 1 0 U1 zinc finger DUF5401 PF17380.2 KXH51967.1 - 0.38 8.8 17.5 0.56 8.2 17.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5401) Exonuc_VII_L PF02601.15 KXH51967.1 - 1.1 8.8 7.7 1.7 8.2 7.7 1.4 1 1 0 1 1 1 0 Exonuclease VII, large subunit DDHD PF02862.17 KXH51967.1 - 1.3 9.1 4.9 0.29 11.3 1.7 1.5 2 0 0 2 2 2 0 DDHD domain UQ_con PF00179.26 KXH51968.1 - 8.9e-35 119.4 0.0 1.1e-34 119.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KXH51968.1 - 0.045 13.4 0.0 0.081 12.6 0.0 1.4 1 1 0 1 1 1 0 Prokaryotic E2 family B Aerolysin PF01117.20 KXH51969.1 - 0.00093 18.5 0.6 0.0014 18.0 0.6 1.2 1 0 0 1 1 1 1 Aerolysin toxin ETX_MTX2 PF03318.13 KXH51969.1 - 0.0045 16.8 4.7 0.0045 16.8 4.7 1.7 2 0 0 2 2 2 1 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 HET PF06985.11 KXH51970.1 - 2.4e-33 115.5 6.4 3.8e-33 114.9 6.4 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Zn_clus PF00172.18 KXH51971.1 - 5.8e-11 42.3 8.2 8.6e-11 41.8 8.2 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KXH51971.1 - 6.3e-06 25.2 0.5 8.2e-06 24.9 0.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain RTA1 PF04479.13 KXH51972.1 - 5.6e-66 222.1 16.7 5.6e-66 222.1 16.7 1.7 1 1 1 2 2 2 1 RTA1 like protein Kei1 PF08552.11 KXH51972.1 - 0.0014 18.5 0.1 0.0034 17.3 0.1 1.6 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 Caveolin PF01146.17 KXH51972.1 - 0.54 10.2 4.8 0.13 12.2 0.8 2.0 2 0 0 2 2 2 0 Caveolin p450 PF00067.22 KXH51974.1 - 7.2e-48 163.5 0.0 1.7e-34 119.4 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 F-box-like PF12937.7 KXH51975.1 - 0.048 13.6 0.0 0.072 13.0 0.0 1.2 1 0 0 1 1 1 0 F-box-like Peptidase_S10 PF00450.22 KXH51976.1 - 1.6e-68 232.1 0.0 2.1e-68 231.7 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.7 KXH51976.1 - 0.0035 18.0 0.2 0.014 16.0 0.0 1.9 1 1 0 2 2 2 1 Alpha/beta hydrolase family NmrA PF05368.13 KXH51977.1 - 6.3e-33 114.3 0.1 1.3e-32 113.2 0.1 1.6 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXH51977.1 - 1.4e-11 44.6 0.0 1.9e-11 44.2 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KXH51977.1 - 1.4e-05 24.7 0.1 2.2e-05 24.1 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.25 KXH51977.1 - 0.00019 21.0 0.3 0.00042 19.8 0.3 1.6 1 0 0 1 1 1 1 short chain dehydrogenase GDP_Man_Dehyd PF16363.5 KXH51977.1 - 0.00036 20.1 0.1 0.00076 19.0 0.0 1.5 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Sacchrp_dh_NADP PF03435.18 KXH51977.1 - 0.015 15.5 0.0 0.024 14.9 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain KR PF08659.10 KXH51977.1 - 0.019 14.9 0.2 0.039 13.9 0.2 1.4 1 0 0 1 1 1 0 KR domain 3Beta_HSD PF01073.19 KXH51977.1 - 0.045 12.8 0.0 0.061 12.3 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family F420_oxidored PF03807.17 KXH51977.1 - 0.045 14.3 0.1 0.098 13.2 0.1 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent PALP PF00291.25 KXH51977.1 - 0.095 12.1 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme Methyltransf_23 PF13489.6 KXH51978.1 - 7.8e-20 71.4 0.0 1.1e-19 70.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH51978.1 - 4.3e-11 43.4 0.0 9.1e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH51978.1 - 5.3e-10 39.3 0.1 7.8e-09 35.5 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH51978.1 - 2.9e-07 31.0 0.0 6.8e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH51978.1 - 4.9e-06 27.2 0.0 1.7e-05 25.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXH51978.1 - 0.0065 16.0 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 KXH51978.1 - 0.0096 15.3 0.0 0.013 14.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.9 KXH51978.1 - 0.012 15.4 0.0 0.028 14.2 0.0 1.6 2 0 0 2 2 2 0 Lysine methyltransferase CMAS PF02353.20 KXH51978.1 - 0.015 14.6 0.0 0.028 13.7 0.0 1.5 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_4 PF02390.17 KXH51978.1 - 0.019 14.5 0.0 0.041 13.4 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase FtsJ PF01728.19 KXH51978.1 - 0.035 14.2 0.0 0.067 13.3 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_23 PF13489.6 KXH51979.1 - 8.5e-25 87.5 0.0 1.2e-24 87.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH51979.1 - 9.4e-10 39.1 0.0 1.8e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH51979.1 - 1.1e-09 38.2 0.0 8.8e-09 35.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH51979.1 - 1.8e-06 28.5 0.0 3.1e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH51979.1 - 5.2e-05 23.9 0.0 0.00036 21.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 KXH51979.1 - 0.0015 18.7 0.0 0.0044 17.1 0.0 1.7 2 0 0 2 2 2 1 FtsJ-like methyltransferase Ubie_methyltran PF01209.18 KXH51979.1 - 0.0058 16.0 0.0 0.073 12.4 0.0 2.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 KXH51979.1 - 0.0062 16.0 0.0 0.014 14.9 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.14 KXH51979.1 - 0.0071 15.9 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 KXH51979.1 - 0.011 15.2 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) GidB PF02527.15 KXH51979.1 - 0.19 11.1 0.0 0.32 10.3 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Ferritin_2 PF13668.6 KXH51982.1 - 2e-15 57.2 1.1 4.1e-15 56.2 0.2 1.8 2 0 0 2 2 2 1 Ferritin-like domain QueF_N PF14819.6 KXH52078.1 - 0.036 14.4 0.0 0.054 13.8 0.0 1.3 1 0 0 1 1 1 0 Nitrile reductase, 7-cyano-7-deazaguanine-reductase N-term PhyH PF05721.13 KXH52079.1 - 3e-05 24.4 0.0 0.25 11.6 0.0 2.4 2 0 0 2 2 2 2 Phytanoyl-CoA dioxygenase (PhyH) Sugar_tr PF00083.24 KXH52080.1 - 9.5e-70 235.7 20.8 1.4e-69 235.2 20.8 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter p450 PF00067.22 KXH52080.1 - 2.5e-30 105.7 0.0 4.7e-30 104.7 0.0 1.4 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 KXH52080.1 - 5.3e-21 74.9 23.1 5.3e-21 74.9 23.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KXH52080.1 - 0.00073 18.1 4.3 0.0024 16.4 1.2 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 KXH52080.1 - 0.2 9.9 7.3 5.4 5.2 6.0 3.0 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family FMO-like PF00743.19 KXH52081.1 - 1.2e-17 63.6 0.0 2.4e-17 62.6 0.0 1.4 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KXH52081.1 - 1.8e-10 40.5 0.0 1.3e-08 34.3 0.0 2.5 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KXH52081.1 - 4.3e-09 36.1 0.0 5e-08 32.6 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXH52081.1 - 1.8e-06 28.1 0.1 1.1e-05 25.5 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXH52081.1 - 0.00051 19.4 0.0 0.011 15.0 0.0 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 KXH52081.1 - 0.094 12.8 0.0 4.5 7.3 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase p450 PF00067.22 KXH52082.1 - 1e-44 153.1 0.0 1.7e-44 152.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Transferase PF02458.15 KXH52084.1 - 2.1e-05 23.4 0.0 6.4e-05 21.8 0.0 1.8 1 1 0 1 1 1 1 Transferase family PSK_trans_fac PF07704.11 KXH52084.1 - 6.4 7.6 5.5 1.4 9.8 0.1 2.5 3 0 0 3 3 3 0 Rv0623-like transcription factor KR PF08659.10 KXH52087.1 - 4.2e-05 23.5 0.1 5.3e-05 23.2 0.1 1.1 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 KXH52087.1 - 0.00021 20.8 0.2 0.00026 20.5 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Shikimate_DH PF01488.20 KXH52087.1 - 0.0012 18.9 0.6 0.0037 17.3 0.2 1.7 1 1 1 2 2 2 1 Shikimate / quinate 5-dehydrogenase p450 PF00067.22 KXH52088.1 - 2.4e-25 89.2 0.0 1.9e-24 86.3 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 DUF521 PF04412.13 KXH52089.1 - 2.2e-137 458.0 0.0 3.5e-137 457.4 0.0 1.3 2 0 0 2 2 2 1 Protein of unknown function (DUF521) DUF126 PF01989.16 KXH52089.1 - 3.7e-28 97.1 0.2 7.2e-28 96.2 0.2 1.5 1 0 0 1 1 1 1 Aconitase X swivel domain Fungal_lectin PF07938.12 KXH52090.1 - 1.3e-09 37.9 5.6 8.5e-07 28.7 0.6 2.1 1 1 1 2 2 2 2 Fungal fucose-specific lectin Lipase_GDSL_2 PF13472.6 KXH52092.1 - 6e-16 59.3 0.1 9.3e-16 58.7 0.1 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KXH52092.1 - 6.8e-07 29.5 0.0 8.3e-06 25.9 0.0 2.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase MFS_1 PF07690.16 KXH52093.1 - 1.6e-28 99.6 24.3 1.6e-28 99.6 24.3 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily RseC_MucC PF04246.12 KXH52093.1 - 0.0066 16.4 1.3 1.1 9.2 0.4 3.1 1 1 0 2 2 2 2 Positive regulator of sigma(E), RseC/MucC DUF485 PF04341.12 KXH52093.1 - 0.15 12.1 8.2 0.96 9.4 0.0 4.0 3 1 1 4 4 4 0 Protein of unknown function, DUF485 Rhomboid PF01694.22 KXH52093.1 - 0.6 10.1 12.8 0.071 13.1 5.4 3.0 2 1 1 3 3 3 0 Rhomboid family DoxX_3 PF13781.6 KXH52093.1 - 5.9 7.6 8.4 0.96 10.1 0.1 3.1 3 0 0 3 3 3 0 DoxX-like family DUF346 PF03984.13 KXH52094.1 - 9.6 6.1 7.4 0.57 10.0 2.1 1.7 2 0 0 2 2 2 0 Repeat of unknown function (DUF346) MRJP PF03022.16 KXH52095.1 - 2.7e-11 43.4 0.0 3.9e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 Major royal jelly protein SGL PF08450.12 KXH52095.1 - 0.0049 16.5 0.9 0.43 10.1 0.1 2.6 1 1 0 2 2 2 2 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 KXH52095.1 - 0.017 15.1 0.9 1.7 8.9 0.1 2.9 2 0 0 2 2 2 0 NHL repeat LVIVD PF08309.11 KXH52095.1 - 0.026 13.8 0.2 0.079 12.3 0.2 1.8 1 0 0 1 1 1 0 LVIVD repeat MIT_LIKE_ACTX PF17556.2 KXH52095.1 - 0.2 12.3 0.0 0.43 11.2 0.0 1.4 1 0 0 1 1 1 0 MIT-like atracotoxin family SNF PF00209.18 KXH52096.1 - 2.4e-73 247.6 31.3 2.4e-73 247.6 31.3 2.7 2 1 0 2 2 2 1 Sodium:neurotransmitter symporter family DUF3810 PF12725.7 KXH52096.1 - 1.4 8.2 3.6 1.9 7.7 1.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) AtuA PF07287.11 KXH52097.1 - 2e-125 418.2 0.1 2.4e-125 417.9 0.1 1.1 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA Hemerythrin PF01814.23 KXH52098.1 - 6.9e-07 29.9 1.1 1e-06 29.4 1.1 1.3 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain DUF2383 PF09537.10 KXH52098.1 - 0.0037 17.6 0.1 0.0062 16.9 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2383) DUF5370 PF17340.2 KXH52099.1 - 0.071 13.0 0.1 0.21 11.5 0.0 1.7 1 1 1 2 2 2 0 Family of unknown function (DUF5370) Chorion_2 PF03964.15 KXH52099.1 - 4.3 8.2 19.0 10 7.0 18.1 2.3 1 1 1 2 2 2 0 Chorion family 2 Glyco_hydro_61 PF03443.14 KXH52100.1 - 3e-58 197.2 0.2 3.5e-58 196.9 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF3394 PF11874.8 KXH52101.1 - 0.14 11.9 0.0 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3394) Sortilin-Vps10 PF15902.5 KXH52102.1 - 2.9e-19 69.2 2.7 9.3e-06 24.7 0.0 6.3 4 2 3 7 7 7 5 Sortilin, neurotensin receptor 3, BNR PF02012.20 KXH52102.1 - 2.2e-09 35.9 28.7 0.2 11.7 0.1 9.2 9 0 0 9 9 9 6 BNR/Asp-box repeat BNR_6 PF15899.5 KXH52102.1 - 7.2e-06 25.6 5.1 0.64 10.2 0.1 6.6 7 0 0 7 7 7 2 BNR-Asp box repeat BNR_2 PF13088.6 KXH52102.1 - 0.0031 16.8 7.6 4.6 6.5 0.1 5.4 3 2 2 5 5 5 2 BNR repeat-like domain CHB_HEX_C PF03174.13 KXH52102.1 - 0.21 11.6 0.8 17 5.4 0.0 4.0 4 0 0 4 4 4 0 Chitobiase/beta-hexosaminidase C-terminal domain DUF2452 PF10504.9 KXH52102.1 - 0.21 11.0 0.0 0.38 10.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2452) GMC_oxred_N PF00732.19 KXH52103.1 - 3.8e-60 203.8 0.0 4.8e-60 203.4 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXH52103.1 - 6.8e-38 130.4 0.2 1.2e-37 129.6 0.2 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KXH52103.1 - 1.8e-05 24.0 0.0 0.031 13.4 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.17 KXH52103.1 - 8.3e-05 21.9 0.2 0.00024 20.4 0.1 1.7 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.12 KXH52103.1 - 0.00012 21.2 0.1 0.00018 20.7 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KXH52103.1 - 0.00015 21.1 0.1 0.091 12.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXH52103.1 - 0.00039 19.7 0.4 0.0029 16.9 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXH52103.1 - 0.00047 20.3 0.1 0.0012 19.0 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXH52103.1 - 0.00077 19.1 1.1 0.0059 16.2 1.1 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KXH52103.1 - 0.052 12.3 0.1 0.087 11.5 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_9 PF13454.6 KXH52103.1 - 0.09 12.8 0.1 0.23 11.5 0.1 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding Trp_halogenase PF04820.14 KXH52103.1 - 0.091 11.6 0.2 0.17 10.7 0.2 1.4 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_8 PF13450.6 KXH52104.1 - 3.3e-12 46.5 0.2 7.4e-12 45.3 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KXH52104.1 - 2.4e-06 27.1 0.0 3.8e-06 26.4 0.0 1.4 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 KXH52104.1 - 0.00016 20.9 0.4 0.00024 20.3 0.4 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KXH52104.1 - 0.00019 21.0 0.0 0.00024 20.6 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 KXH52104.1 - 0.00019 21.1 0.5 0.00033 20.3 0.5 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KXH52104.1 - 0.00049 19.4 0.2 0.00082 18.7 0.2 1.2 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 KXH52104.1 - 0.00052 18.8 0.2 0.00089 18.1 0.2 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.14 KXH52104.1 - 0.0078 15.5 0.1 0.014 14.6 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXH52104.1 - 0.045 14.3 0.5 0.18 12.4 0.1 2.1 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXH52104.1 - 0.1 11.8 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.19 KXH52104.1 - 0.12 11.7 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 GMC oxidoreductase TrkA_N PF02254.18 KXH52104.1 - 0.13 12.5 0.2 0.28 11.5 0.2 1.5 1 0 0 1 1 1 0 TrkA-N domain GIDA PF01134.22 KXH52104.1 - 0.21 10.6 0.5 0.31 10.1 0.5 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Tannase PF07519.11 KXH52106.1 - 8.5e-115 384.3 0.6 1.1e-114 384.0 0.6 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Hydrolase_4 PF12146.8 KXH52106.1 - 0.00094 18.5 0.0 0.071 12.4 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KXH52106.1 - 0.025 14.2 0.0 0.12 12.0 0.0 1.9 1 1 0 1 1 1 0 alpha/beta hydrolase fold p450 PF00067.22 KXH52107.1 - 6.5e-39 134.0 0.0 8.6e-39 133.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Esterase_phd PF10503.9 KXH52108.1 - 2e-22 79.8 2.1 3.7e-22 78.9 2.1 1.3 1 0 0 1 1 1 1 Esterase PHB depolymerase CBM_1 PF00734.18 KXH52108.1 - 1.8e-15 56.6 8.8 6.5e-15 54.8 8.8 2.1 1 0 0 1 1 1 1 Fungal cellulose binding domain Peptidase_S9 PF00326.21 KXH52108.1 - 9.1e-10 38.4 4.0 1.5e-09 37.7 4.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 KXH52108.1 - 0.025 14.2 0.3 0.034 13.8 0.3 1.3 1 0 0 1 1 1 0 Putative esterase Aa_trans PF01490.18 KXH52109.1 - 3e-83 279.8 19.0 3.5e-83 279.6 19.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein CAAD PF14159.6 KXH52109.1 - 2.6 7.9 7.1 0.64 9.9 0.9 3.1 3 0 0 3 3 3 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase Vps36-NZF-N PF16988.5 KXH52110.1 - 0.073 12.5 0.4 0.15 11.5 0.4 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain DUF2256 PF10013.9 KXH52110.1 - 0.11 12.6 7.2 1.9 8.7 1.8 2.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-BED PF02892.15 KXH52110.1 - 0.12 12.4 0.1 0.28 11.2 0.1 1.6 1 0 0 1 1 1 0 BED zinc finger An_peroxidase PF03098.15 KXH52112.1 - 6.6e-31 107.5 0.0 6e-22 77.9 0.0 3.4 1 1 1 2 2 2 2 Animal haem peroxidase p450 PF00067.22 KXH52112.1 - 2.3e-07 30.0 0.0 6.9e-07 28.4 0.0 1.7 2 0 0 2 2 2 1 Cytochrome P450 DUF433 PF04255.14 KXH52112.1 - 0.14 12.0 0.1 21 5.1 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF433) DUF2235 PF09994.9 KXH52113.1 - 4.4e-89 298.6 0.1 6.6e-89 298.1 0.1 1.3 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Amidase PF01425.21 KXH52114.1 - 2.3e-27 96.1 1.4 3.6e-27 95.4 1.4 1.2 1 0 0 1 1 1 1 Amidase Tautomerase_3 PF14832.6 KXH52114.1 - 2.6e-08 34.2 0.0 5.2e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Putative oxalocrotonate tautomerase enzyme p450 PF00067.22 KXH52115.1 - 3.5e-41 141.4 0.0 4.2e-41 141.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PGG PF13962.6 KXH52116.1 - 0.16 11.8 0.3 0.25 11.2 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function COesterase PF00135.28 KXH52117.1 - 5.5e-84 282.9 0.1 7.3e-84 282.5 0.1 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXH52117.1 - 4.1e-07 30.1 0.2 4.9e-06 26.5 0.2 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KXH52117.1 - 3.2e-05 23.5 1.0 5.9e-05 22.6 1.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family GspH PF12019.8 KXH52117.1 - 0.12 12.8 1.9 21 5.6 0.3 3.0 3 0 0 3 3 3 0 Type II transport protein GspH ADH_zinc_N PF00107.26 KXH52119.1 - 1.2e-26 93.2 0.1 2e-26 92.5 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXH52119.1 - 1.2e-20 74.9 0.0 2.8e-20 73.7 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXH52119.1 - 1.9e-08 34.2 0.1 4.9e-08 32.8 0.1 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 KXH52119.1 - 0.02 14.8 0.0 0.041 13.8 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase AlaDh_PNT_C PF01262.21 KXH52119.1 - 0.048 12.9 0.1 0.081 12.2 0.1 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 KXH52120.1 - 2.5e-93 313.5 0.7 3.1e-93 313.1 0.7 1.0 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 KXH52120.1 - 9e-07 28.5 0.1 3e-06 26.7 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 KXH52120.1 - 6e-06 26.4 0.1 1.9e-05 24.8 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXH52120.1 - 7.8e-05 22.4 4.2 0.00047 19.8 4.2 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 KXH52120.1 - 0.00032 19.9 0.1 0.00032 19.9 0.1 1.6 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 KXH52120.1 - 0.00054 19.3 0.5 0.0045 16.3 0.1 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KXH52120.1 - 0.00059 19.3 0.0 0.001 18.5 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KXH52120.1 - 0.00068 18.5 5.1 0.006 15.3 0.2 2.4 2 0 0 2 2 2 2 HI0933-like protein Thi4 PF01946.17 KXH52120.1 - 0.0019 17.5 0.3 0.0077 15.5 0.1 1.9 2 0 0 2 2 2 1 Thi4 family Pyr_redox_3 PF13738.6 KXH52120.1 - 0.027 13.8 0.3 0.066 12.5 0.2 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXH52120.1 - 0.063 13.8 0.4 1.2 9.7 0.2 2.9 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF3273 PF11677.8 KXH52121.1 - 0.029 13.7 7.3 0.026 13.9 3.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3273) Fungal_trans PF04082.18 KXH52122.1 - 1.9e-18 66.5 0.1 3.1e-18 65.7 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH52122.1 - 2e-06 27.8 7.4 3.8e-06 26.9 7.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.12 KXH52122.1 - 5.8 7.5 11.0 1.5 9.4 2.6 2.3 1 1 1 2 2 2 0 Dickkopf N-terminal cysteine-rich region Dala_Dala_lig_C PF07478.13 KXH52123.1 - 1.5e-09 37.7 0.0 2.2e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_4 PF13535.6 KXH52123.1 - 0.00087 18.9 0.0 0.0051 16.4 0.0 2.1 1 1 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 KXH52123.1 - 0.0026 17.3 0.0 0.0044 16.6 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_3 PF02655.14 KXH52123.1 - 0.0047 17.0 0.0 0.0074 16.4 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 KXH52123.1 - 0.011 15.5 0.0 0.017 14.9 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain RimK PF08443.11 KXH52123.1 - 0.048 13.2 0.0 0.089 12.4 0.0 1.4 1 0 0 1 1 1 0 RimK-like ATP-grasp domain DUF5444 PF17519.2 KXH52123.1 - 0.18 11.8 0.2 1.1 9.3 0.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5444) SGL PF08450.12 KXH52125.1 - 4.8e-28 98.4 0.1 6.5e-28 97.9 0.1 1.2 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 KXH52125.1 - 2.9e-05 24.2 0.0 9.6e-05 22.5 0.0 1.9 2 0 0 2 2 2 1 Arylesterase Str_synth PF03088.16 KXH52125.1 - 0.00019 21.5 0.0 0.00048 20.2 0.0 1.8 1 1 0 1 1 1 1 Strictosidine synthase NHL PF01436.21 KXH52125.1 - 0.07 13.2 0.4 2.5 8.3 0.0 3.4 3 0 0 3 3 3 0 NHL repeat Arginase PF00491.21 KXH52126.1 - 1.2e-20 74.1 0.0 1.5e-20 73.9 0.0 1.0 1 0 0 1 1 1 1 Arginase family DUF4732 PF15876.5 KXH52126.1 - 0.039 14.0 0.0 0.062 13.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4732) PD40 PF07676.12 KXH52127.1 - 0.012 15.5 0.4 0.037 14.0 0.1 2.0 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Proteasome_A_N PF10584.9 KXH52127.1 - 0.15 11.8 0.1 0.35 10.6 0.1 1.7 1 0 0 1 1 1 0 Proteasome subunit A N-terminal signature MFS_1 PF07690.16 KXH52128.1 - 9.9e-31 106.9 45.0 5.8e-29 101.1 30.9 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH52128.1 - 1.6e-12 47.0 6.9 1.6e-12 47.0 6.9 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KXH52128.1 - 0.00022 19.8 2.7 0.00035 19.1 2.7 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 KXH52128.1 - 0.38 9.0 7.5 0.92 7.7 0.5 2.5 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family MatE PF01554.18 KXH52129.1 - 1e-51 174.8 20.8 4e-26 91.6 5.4 2.3 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 KXH52129.1 - 2.5e-08 34.1 4.8 2.5e-08 34.1 4.8 3.9 3 1 0 3 3 3 2 Polysaccharide biosynthesis C-terminal domain Arginase PF00491.21 KXH52130.1 - 6e-67 226.1 0.1 6.9e-67 225.9 0.1 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 KXH52130.1 - 0.019 15.2 0.2 0.032 14.5 0.1 1.5 1 1 1 2 2 2 0 UPF0489 domain Fungal_trans_2 PF11951.8 KXH52131.1 - 2.4e-22 79.3 1.7 2.4e-22 79.3 1.7 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH52131.1 - 2.5e-07 30.7 11.0 4.8e-07 29.8 11.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aminotran_3 PF00202.21 KXH52132.1 - 1.2e-58 198.7 0.0 1.6e-58 198.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III FAA_hydrolase_N PF09298.11 KXH52133.1 - 0.14 12.4 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 Fumarylacetoacetase N-terminal AA_permease_2 PF13520.6 KXH52134.1 - 2.6e-47 161.6 49.4 3.2e-47 161.3 49.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXH52134.1 - 3e-27 95.4 44.9 3.8e-27 95.0 44.9 1.1 1 0 0 1 1 1 1 Amino acid permease AcrZ PF10766.9 KXH52134.1 - 2.3 7.9 8.7 3.8 7.1 3.2 3.4 2 0 0 2 2 2 0 Multidrug efflux pump-associated protein AcrZ Glyco_hydro_43 PF04616.14 KXH52135.1 - 2.7e-35 122.1 3.5 3.6e-35 121.7 3.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 KXH52135.1 - 1.9e-21 76.7 0.0 2.8e-21 76.2 0.0 1.2 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain Methyltransf_23 PF13489.6 KXH52136.1 - 2.2e-24 86.1 0.0 3.3e-24 85.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH52136.1 - 3.9e-09 37.1 0.0 1.3e-08 35.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH52136.1 - 5.7e-08 32.7 0.0 0.00079 19.2 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 KXH52136.1 - 2.5e-06 28.0 0.0 4.7e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXH52136.1 - 6.5e-05 22.5 0.0 0.00011 21.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 KXH52136.1 - 0.00014 22.5 0.0 0.0013 19.4 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 KXH52136.1 - 0.004 16.5 0.0 0.065 12.5 0.0 2.1 2 0 0 2 2 2 1 O-methyltransferase domain FtsJ PF01728.19 KXH52136.1 - 0.049 13.7 0.2 0.16 12.0 0.0 1.9 3 1 0 3 3 3 0 FtsJ-like methyltransferase PrmA PF06325.13 KXH52136.1 - 0.065 12.6 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.17 KXH52136.1 - 0.12 11.8 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_16 PF10294.9 KXH52136.1 - 0.15 11.8 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Glyco_hydro_35 PF01301.19 KXH52137.1 - 1.8e-06 27.8 0.0 4.6e-06 26.5 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 35 DUF5597 PF18120.1 KXH52137.1 - 9.1e-05 22.6 0.0 0.00017 21.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5597) Glyco_hydro_42 PF02449.15 KXH52137.1 - 0.00091 18.7 0.0 0.0022 17.4 0.0 1.6 2 0 0 2 2 2 1 Beta-galactosidase Cellulase PF00150.18 KXH52137.1 - 0.014 14.8 0.0 0.031 13.7 0.0 1.5 2 0 0 2 2 2 0 Cellulase (glycosyl hydrolase family 5) zf-C2H2_12 PF18658.1 KXH52138.1 - 0.012 15.1 0.2 0.018 14.6 0.2 1.3 1 0 0 1 1 1 0 Zinc-finger C2H2-type zf-C2H2 PF00096.26 KXH52138.1 - 0.017 15.6 2.5 0.027 14.9 2.5 1.3 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-BED PF02892.15 KXH52138.1 - 0.071 13.1 1.8 0.13 12.4 1.8 1.4 1 0 0 1 1 1 0 BED zinc finger DUF629 PF04780.12 KXH52138.1 - 0.12 10.8 0.2 0.14 10.7 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF629) Ribosomal_L10 PF00466.20 KXH52138.1 - 0.14 12.3 0.0 0.22 11.7 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L10 zf-C2H2_4 PF13894.6 KXH52138.1 - 0.14 13.0 1.6 0.24 12.3 1.6 1.4 1 0 0 1 1 1 0 C2H2-type zinc finger MFS_1 PF07690.16 KXH52139.1 - 9.7e-33 113.5 38.2 9.7e-33 113.5 38.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 KXH52140.1 - 3.1e-29 102.0 33.7 4.2e-28 98.3 31.4 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 KXH52140.1 - 0.0033 16.8 13.2 0.022 14.1 7.3 2.7 2 2 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB OATP PF03137.20 KXH52140.1 - 0.0089 14.4 8.6 0.021 13.1 3.8 2.3 1 1 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family Amidohydro_1 PF01979.20 KXH52141.1 - 1.5e-45 156.0 0.0 2.2e-45 155.5 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KXH52141.1 - 1.3e-17 64.5 0.5 1.5e-11 44.5 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family SO_alpha_A3 PF17806.1 KXH52141.1 - 0.14 12.5 0.0 2.5 8.5 0.0 2.3 2 0 0 2 2 2 0 Sarcosine oxidase A3 domain Fungal_trans PF04082.18 KXH52142.1 - 1.2e-25 90.0 0.1 1.9e-25 89.4 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH52142.1 - 0.0056 16.8 10.2 0.011 15.9 10.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RTA1 PF04479.13 KXH52143.1 - 1.1e-51 175.4 11.1 1.1e-51 175.4 11.1 1.5 1 1 0 1 1 1 1 RTA1 like protein AAA_33 PF13671.6 KXH52143.1 - 6.4e-13 49.1 0.0 1.5e-12 47.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KXH52143.1 - 8.6e-07 28.4 0.0 2.7e-06 26.8 0.0 1.7 1 1 0 1 1 1 1 Zeta toxin SKI PF01202.22 KXH52143.1 - 0.0091 16.1 0.0 0.032 14.3 0.0 1.9 1 1 0 1 1 1 1 Shikimate kinase APS_kinase PF01583.20 KXH52143.1 - 0.014 15.3 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase CoaE PF01121.20 KXH52143.1 - 0.018 14.7 0.0 0.033 13.9 0.0 1.4 1 0 0 1 1 1 0 Dephospho-CoA kinase AAA_18 PF13238.6 KXH52143.1 - 0.026 15.1 0.0 0.085 13.4 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 KXH52143.1 - 0.074 13.5 0.0 0.71 10.3 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Hydin_ADK PF17213.3 KXH52143.1 - 0.091 13.0 0.0 0.17 12.2 0.0 1.3 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain KTI12 PF08433.10 KXH52143.1 - 0.12 11.8 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_28 PF13521.6 KXH52143.1 - 0.13 12.5 0.1 0.25 11.6 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.6 KXH52143.1 - 0.16 12.4 0.0 1.2 9.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF2964 PF11177.8 KXH52143.1 - 0.5 10.6 3.3 9.6 6.5 0.5 3.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2964) p450 PF00067.22 KXH52145.1 - 8.8e-48 163.2 0.0 1.3e-47 162.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ASCH PF04266.14 KXH52146.1 - 9.5e-20 71.2 0.1 1.2e-19 70.9 0.1 1.1 1 0 0 1 1 1 1 ASCH domain Lipase_GDSL_2 PF13472.6 KXH52147.1 - 9.4e-10 39.2 0.8 1.7e-09 38.3 0.8 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KXH52147.1 - 5.6e-07 29.7 0.0 6.5e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase SurE PF01975.17 KXH52149.1 - 0.015 15.1 3.9 0.016 15.0 3.9 1.2 1 0 0 1 1 1 0 Survival protein SurE FAM199X PF15814.5 KXH52149.1 - 5.6 5.9 13.1 7.2 5.6 13.1 1.2 1 0 0 1 1 1 0 Protein family FAM199X CVNH PF08881.10 KXH52151.1 - 0.0009 19.9 0.3 0.011 16.4 0.6 2.1 1 1 1 2 2 2 1 CVNH domain SAD_SRA PF02182.17 KXH52152.1 - 9.2e-16 57.9 0.0 2.5e-07 30.5 0.1 2.2 1 1 1 2 2 2 2 SAD/SRA domain KH_1 PF00013.29 KXH52153.1 - 0.059 13.2 0.0 0.22 11.4 0.0 1.9 2 0 0 2 2 2 0 KH domain SGL PF08450.12 KXH52154.1 - 0.00013 21.7 1.1 0.021 14.4 0.0 2.7 3 0 0 3 3 3 2 SMP-30/Gluconolactonase/LRE-like region GSDH PF07995.11 KXH52154.1 - 0.16 11.3 1.3 0.91 8.8 0.7 2.5 2 1 1 3 3 3 0 Glucose / Sorbosone dehydrogenase DUF4448 PF14610.6 KXH52155.1 - 2.9e-27 95.7 0.0 2.1e-18 66.8 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF4448) GT87 PF09594.10 KXH52155.1 - 0.042 13.5 1.5 0.11 12.2 0.1 2.0 2 0 0 2 2 2 0 Glycosyltransferase family 87 DUF4381 PF14316.6 KXH52155.1 - 0.12 12.6 0.2 0.2 11.9 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) AMP-binding PF00501.28 KXH52156.1 - 2.4e-72 243.8 0.0 3.1e-72 243.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXH52156.1 - 9.5e-11 42.5 0.1 2e-10 41.5 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GH3 PF03321.13 KXH52156.1 - 0.15 10.9 0.0 9.8 4.9 0.0 2.1 2 0 0 2 2 2 0 GH3 auxin-responsive promoter AtuA PF07287.11 KXH52157.1 - 2.4e-127 424.5 0.0 3e-127 424.2 0.0 1.1 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA MaoC_dehydratas PF01575.19 KXH52158.1 - 3.7e-23 81.4 0.0 6e-23 80.7 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 KXH52158.1 - 2.2e-06 27.8 0.0 0.0002 21.5 0.0 2.3 2 0 0 2 2 2 2 N-terminal half of MaoC dehydratase ECH_1 PF00378.20 KXH52159.1 - 1.4e-42 145.8 0.0 1.7e-42 145.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXH52159.1 - 7.2e-19 68.5 0.1 4.7e-17 62.5 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 KXH52160.1 - 7.2e-53 179.5 0.0 8.6e-53 179.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXH52160.1 - 9.3e-21 74.7 0.0 1.3e-19 70.9 0.0 1.9 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase TRI12 PF06609.13 KXH52161.1 - 1.7e-81 274.5 17.4 2e-81 274.2 17.4 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 KXH52161.1 - 2.7e-28 98.9 48.7 8e-28 97.4 46.2 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH52161.1 - 1.5e-10 40.6 3.9 1.5e-10 40.6 3.9 2.7 3 0 0 3 3 3 1 Sugar (and other) transporter Zn_clus PF00172.18 KXH52162.1 - 9.4e-09 35.3 8.7 2e-08 34.2 8.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Amidase PF01425.21 KXH52163.1 - 1.5e-92 310.9 0.1 5e-83 279.5 0.0 2.0 2 0 0 2 2 2 2 Amidase HET PF06985.11 KXH52164.1 - 4.4e-16 59.6 0.0 1.2e-15 58.1 0.0 1.8 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Dioxygenase_C PF00775.21 KXH52165.1 - 1.3e-09 37.7 0.4 2.8e-09 36.7 0.4 1.6 1 1 0 1 1 1 1 Dioxygenase MFS_1 PF07690.16 KXH52168.1 - 1.2e-22 80.3 27.5 2.1e-17 63.1 20.7 2.9 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KXH52168.1 - 2.2e-08 33.0 1.2 3.2e-08 32.5 1.2 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) CN_hydrolase PF00795.22 KXH52169.1 - 3e-21 75.9 0.0 4.8e-21 75.3 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Iso_dh PF00180.20 KXH52170.1 - 2.8e-117 391.7 0.0 3.3e-117 391.5 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase p450 PF00067.22 KXH52171.1 - 1.3e-47 162.6 1.0 7.7e-34 117.2 0.2 2.2 2 0 0 2 2 2 2 Cytochrome P450 Kinesin PF00225.23 KXH52172.1 - 1.2e-80 271.0 0.0 1.7e-80 270.4 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KXH52172.1 - 1.8e-19 70.1 0.0 3.2e-19 69.3 0.0 1.4 1 0 0 1 1 1 1 Microtubule binding HHH_5 PF14520.6 KXH52172.1 - 0.014 16.0 0.1 0.17 12.5 0.1 2.6 1 1 1 2 2 2 0 Helix-hairpin-helix domain HHH_3 PF12836.7 KXH52172.1 - 0.017 15.4 0.2 0.074 13.3 0.0 2.2 2 0 0 2 2 2 0 Helix-hairpin-helix motif PBP1_TM PF14812.6 KXH52172.1 - 0.028 14.8 2.1 0.095 13.1 2.1 1.9 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal MerR-DNA-bind PF09278.11 KXH52172.1 - 4.9 7.8 7.7 1 10.0 0.6 3.1 2 1 1 3 3 3 0 MerR, DNA binding AIM24 PF01987.17 KXH52173.1 - 1.1e-50 172.2 0.0 1.4e-50 171.9 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 Tax PF02959.16 KXH52173.1 - 0.043 13.3 0.1 0.094 12.2 0.1 1.5 1 0 0 1 1 1 0 HTLV Tax MFS_1 PF07690.16 KXH52174.1 - 3.3e-32 111.8 82.9 1.8e-25 89.7 46.7 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH52174.1 - 0.02 13.7 46.7 0.032 13.1 17.2 3.6 2 2 2 4 4 4 0 Sugar (and other) transporter Fungal_trans PF04082.18 KXH52175.1 - 3e-08 33.0 0.0 5.8e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH52175.1 - 0.00036 20.6 2.1 0.00076 19.6 2.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain OPT PF03169.15 KXH52177.1 - 1.1e-135 453.8 54.1 1.2e-135 453.6 54.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Ctr PF04145.15 KXH52178.1 - 3.2e-11 44.1 0.0 4.2e-11 43.7 0.0 1.4 1 1 0 1 1 1 1 Ctr copper transporter family Chlorophyllase PF07224.11 KXH52178.1 - 0.1 11.6 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase HET PF06985.11 KXH52179.1 - 0.017 15.5 0.0 0.029 14.7 0.0 1.4 1 0 0 1 1 1 0 Heterokaryon incompatibility protein (HET) DUF4188 PF13826.6 KXH52180.1 - 5.5e-34 117.0 0.1 8e-34 116.5 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4188) Dehydratase_hem PF13816.6 KXH52180.1 - 0.007 15.8 0.0 0.015 14.7 0.0 1.4 1 1 0 1 1 1 1 Haem-containing dehydratase MFS_1 PF07690.16 KXH52181.1 - 1.4e-29 103.2 24.6 6e-25 87.9 5.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily BLUF PF04940.12 KXH52181.1 - 0.11 12.6 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 Sensors of blue-light using FAD 2OG-FeII_Oxy PF03171.20 KXH52182.1 - 3.5e-13 49.9 0.0 7e-13 48.9 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 KXH52182.1 - 1.6e-12 48.2 0.0 3.1e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal NAD_binding_2 PF03446.15 KXH52183.1 - 1.7e-25 90.1 0.8 2.8e-25 89.3 0.8 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KXH52183.1 - 4.2e-09 36.7 0.0 9.2e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Shikimate_DH PF01488.20 KXH52183.1 - 4.5e-05 23.5 0.0 7.6e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 KXH52183.1 - 8.3e-05 23.1 0.1 0.00062 20.3 0.0 2.3 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 KXH52183.1 - 0.019 14.3 0.0 0.033 13.6 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GST_C PF00043.25 KXH52184.1 - 7.9e-13 48.4 0.0 1.2e-12 47.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KXH52184.1 - 4.5e-10 39.4 0.4 1.7e-09 37.6 0.1 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KXH52184.1 - 8.2e-08 32.4 0.0 1.5e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KXH52184.1 - 3.4e-07 30.5 0.0 7.1e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KXH52184.1 - 0.0011 19.3 0.0 0.0022 18.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GET2 PF08690.10 KXH52184.1 - 0.045 13.4 0.0 0.058 13.1 0.0 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 Fungal_trans PF04082.18 KXH52185.1 - 7.2e-23 81.0 0.3 1.1e-22 80.4 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DIOX_N PF14226.6 KXH52186.1 - 2.5e-14 54.0 0.0 1.2e-13 51.8 0.0 1.9 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KXH52186.1 - 4.3e-09 36.8 0.1 9.1e-09 35.7 0.1 1.7 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Fungal_trans PF04082.18 KXH52187.1 - 1.5e-06 27.5 0.0 2.6e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain TetR_C_6 PF13977.6 KXH52187.1 - 0.071 13.3 0.6 14 5.9 0.1 2.8 2 0 0 2 2 2 0 BetI-type transcriptional repressor, C-terminal PhyH PF05721.13 KXH52188.1 - 7.3e-13 49.3 0.0 1.3e-12 48.5 0.0 1.4 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Sugar_tr PF00083.24 KXH52189.1 - 2.4e-104 349.8 30.0 2.6e-69 234.3 12.9 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KXH52189.1 - 1.9e-13 50.1 43.6 4.9e-13 48.7 36.0 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily GST_C_3 PF14497.6 KXH52190.1 - 1.8e-08 34.4 0.0 4.5e-08 33.2 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KXH52190.1 - 1.6e-06 28.2 0.0 0.00013 22.2 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KXH52190.1 - 2.2e-06 27.9 0.0 1.7e-05 25.1 0.0 2.3 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KXH52190.1 - 2.8e-05 24.5 0.0 6.1e-05 23.4 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KXH52190.1 - 3e-05 24.2 0.0 0.00024 21.3 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KXH52190.1 - 0.024 14.6 0.0 0.29 11.2 0.0 2.4 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Glyco_transf_20 PF00982.21 KXH52192.1 - 1.8e-145 485.3 0.0 2.6e-145 484.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 KXH52192.1 - 3.1e-70 235.9 0.0 5.3e-70 235.2 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase Peptidase_S8 PF00082.22 KXH52194.1 - 8.5e-43 146.7 2.3 1.4e-42 146.0 2.3 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 KXH52194.1 - 0.0047 17.6 0.0 0.0099 16.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 BTB PF00651.31 KXH52195.1 - 4.6e-12 46.2 0.0 2.1e-11 44.1 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain Mo-co_dimer PF03404.16 KXH52198.1 - 2.8e-05 24.2 1.9 3.8e-05 23.7 1.9 1.2 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain muHD PF10291.9 KXH52198.1 - 0.0067 15.9 0.2 0.0076 15.7 0.2 1.1 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain Peptidase_M6 PF05547.11 KXH52199.1 - 0.039 12.3 0.6 1.2 7.4 0.1 2.1 2 0 0 2 2 2 0 Immune inhibitor A peptidase M6 Pol_alpha_B_N PF08418.10 KXH52200.1 - 4.5 7.2 10.1 9.9 6.0 6.5 2.3 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal Macoilin PF09726.9 KXH52200.1 - 5.2 5.5 5.6 9.3 4.7 5.6 1.4 1 0 0 1 1 1 0 Macoilin family PhoD PF09423.10 KXH52201.1 - 5.3e-116 387.5 2.0 6.5e-116 387.2 2.0 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase PhoD_N PF16655.5 KXH52201.1 - 1.3e-32 112.2 0.2 2.8e-32 111.1 0.2 1.6 1 0 0 1 1 1 1 PhoD-like phosphatase, N-terminal domain Pur_ac_phosph_N PF16656.5 KXH52201.1 - 0.00075 20.0 0.8 0.0026 18.3 0.8 2.0 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain DUF5012 PF16404.5 KXH52201.1 - 0.46 10.6 3.9 0.34 11.0 0.2 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF5012) Ecm33 PF12454.8 KXH52202.1 - 0.016 15.3 0.5 0.038 14.1 0.5 1.6 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein Recep_L_domain PF01030.24 KXH52202.1 - 0.14 12.3 0.0 3.5 7.8 0.0 2.7 2 1 1 3 3 3 0 Receptor L domain Ferric_reduct PF01794.19 KXH52203.1 - 1.6e-18 67.0 5.0 1.6e-18 67.0 5.0 2.5 2 1 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.21 KXH52203.1 - 0.00013 22.6 0.0 0.00025 21.7 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_8 PF08022.12 KXH52203.1 - 0.0071 16.4 0.0 0.016 15.2 0.0 1.6 1 1 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 KXH52203.1 - 0.019 15.1 0.0 0.037 14.1 0.0 1.5 1 0 0 1 1 1 0 Ferric reductase NAD binding domain DUF2839 PF10999.8 KXH52203.1 - 0.14 12.6 1.9 0.58 10.6 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2839) NmrA PF05368.13 KXH52204.1 - 2.2e-16 60.1 0.0 2.7e-16 59.8 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXH52204.1 - 1.3e-12 48.0 0.0 2.5e-12 47.1 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KXH52204.1 - 0.0023 17.4 0.1 0.005 16.3 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 KXH52204.1 - 0.04 14.4 0.2 0.17 12.4 0.1 2.0 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Sugar_tr PF00083.24 KXH52205.1 - 5.1e-79 266.3 10.2 5.8e-79 266.1 10.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH52205.1 - 1.2e-13 50.8 13.3 1.2e-13 50.8 13.3 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 KXH52205.1 - 0.00021 20.7 1.7 0.00046 19.6 1.7 1.5 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB Potex_coat PF06184.11 KXH52205.1 - 0.09 12.4 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Potexvirus coat protein AMP-binding PF00501.28 KXH52206.1 - 1.8e-75 254.1 0.1 2.2e-75 253.9 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXH52206.1 - 1.8e-15 57.7 0.2 4.4e-15 56.4 0.2 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain LysM PF01476.20 KXH52207.1 - 3.5e-21 75.0 0.5 1.6e-10 40.8 0.2 2.1 2 0 0 2 2 2 2 LysM domain DEC-1_N PF04625.13 KXH52207.1 - 0.23 10.4 1.8 0.24 10.4 1.8 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region DUF4763 PF15960.5 KXH52254.1 - 0.025 13.9 0.0 0.038 13.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) UBA_3 PF09288.10 KXH52255.1 - 0.021 14.6 0.5 0.049 13.4 0.5 1.6 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain FapA PF03961.13 KXH52255.1 - 0.16 10.5 3.2 0.25 9.9 3.2 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A CCDC-167 PF15188.6 KXH52255.1 - 0.19 12.1 2.4 0.46 10.9 2.4 1.6 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 DUF1664 PF07889.12 KXH52255.1 - 0.3 11.1 0.7 0.65 10.0 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Macoilin PF09726.9 KXH52255.1 - 0.73 8.3 6.8 1 7.8 6.8 1.2 1 0 0 1 1 1 0 Macoilin family zf-C4H2 PF10146.9 KXH52255.1 - 8.3 6.7 15.5 0.26 11.6 4.2 2.5 2 0 0 2 2 2 0 Zinc finger-containing protein RRM_1 PF00076.22 KXH52256.1 - 1.2e-43 146.8 0.7 8.8e-20 70.3 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 KXH52256.1 - 3.4e-23 82.6 0.1 1.2e-22 80.8 0.1 2.0 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_occluded PF16842.5 KXH52256.1 - 0.0012 18.7 0.0 0.29 11.0 0.0 3.1 3 0 0 3 3 3 1 Occluded RNA-recognition motif RRM_3 PF08777.11 KXH52256.1 - 0.004 17.2 1.7 0.1 12.7 0.0 3.1 3 1 0 3 3 3 1 RNA binding motif Nup35_RRM_2 PF14605.6 KXH52256.1 - 0.0047 16.9 0.0 0.68 10.0 0.0 2.8 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 KXH52256.1 - 0.018 15.2 0.0 1.7 8.8 0.0 2.6 2 0 0 2 2 2 0 RNA recognition motif PHM7_cyt PF14703.6 KXH52256.1 - 0.045 14.0 0.2 1.6 8.9 0.2 3.1 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter Cyt-b5 PF00173.28 KXH52257.1 - 6e-18 64.8 2.1 1e-17 64.1 0.2 2.2 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.13 KXH52257.1 - 3.8e-11 43.5 19.9 5.9e-11 42.8 19.4 1.6 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Anth_synt_I_N PF04715.13 KXH52257.1 - 0.052 13.8 0.1 0.094 12.9 0.1 1.4 1 0 0 1 1 1 0 Anthranilate synthase component I, N terminal region Het-C PF07217.11 KXH52258.1 - 1.3e-286 951.6 0.0 1.7e-286 951.3 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C PP2C PF00481.21 KXH52259.1 - 1.4e-39 136.3 0.0 1.3e-33 116.7 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 KXH52259.1 - 6.9e-05 22.6 0.0 0.00012 21.7 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C BTB PF00651.31 KXH52260.1 - 0.0077 16.5 0.9 4.3 7.6 0.0 3.0 4 0 0 4 4 4 2 BTB/POZ domain FTR1 PF03239.14 KXH52261.1 - 4.2e-81 272.5 9.6 5.3e-81 272.1 9.6 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family Ferlin_C PF16165.5 KXH52261.1 - 0.31 11.0 0.0 0.31 11.0 0.0 2.2 3 0 0 3 3 3 0 Ferlin C-terminus SUR7 PF06687.12 KXH52261.1 - 1 8.9 9.1 0.15 11.6 2.4 2.4 2 0 0 2 2 2 0 SUR7/PalI family HlyIII PF03006.20 KXH52261.1 - 8.6 6.0 9.9 7.2 6.3 0.7 2.6 3 0 0 3 3 3 0 Haemolysin-III related FeoB_associated PF12669.7 KXH52261.1 - 9.1 6.8 13.2 12 6.4 0.1 4.3 4 0 0 4 4 4 0 FeoB-associated Cys-rich membrane protein Cu-oxidase_2 PF07731.14 KXH52262.1 - 1.9e-44 150.7 7.0 1.5e-40 138.1 0.4 2.8 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 KXH52262.1 - 9.8e-42 141.7 6.7 6e-39 132.7 2.3 3.9 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase PF00394.22 KXH52262.1 - 6.2e-41 140.2 1.5 2.2e-36 125.4 0.1 2.9 2 1 0 2 2 2 2 Multicopper oxidase Cupredoxin_1 PF13473.6 KXH52262.1 - 0.00065 19.8 0.0 9 6.5 0.0 3.7 3 0 0 3 3 3 2 Cupredoxin-like domain CDP-OH_P_transf PF01066.21 KXH52263.1 - 1.5e-12 48.1 0.3 1.5e-12 48.1 0.3 2.2 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase OMPdecase PF00215.24 KXH52266.1 - 1.1e-102 342.5 0.0 1.2e-102 342.3 0.0 1.0 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Fungal_trans PF04082.18 KXH52267.1 - 3.7e-10 39.3 0.0 6.4e-10 38.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH52267.1 - 4.9e-07 29.8 12.4 8.5e-07 29.0 12.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf_CCCH_4 PF18345.1 KXH52268.1 - 4 7.6 7.1 10 6.3 2.1 2.9 2 0 0 2 2 2 0 Zinc finger domain Torus PF16131.5 KXH52268.1 - 4.6 8.0 8.0 0.27 11.9 0.3 2.5 2 0 0 2 2 2 0 Torus domain SRP19 PF01922.17 KXH52269.1 - 5.9e-33 113.7 0.0 1e-32 112.9 0.0 1.4 1 0 0 1 1 1 1 SRP19 protein Dynactin PF12455.8 KXH52270.1 - 1.4e-112 375.6 11.5 1.4e-112 375.6 11.5 5.0 4 1 2 6 6 6 1 Dynein associated protein CAP_GLY PF01302.25 KXH52270.1 - 1e-22 79.9 0.4 1.8e-22 79.1 0.4 1.4 1 0 0 1 1 1 1 CAP-Gly domain DUF2353 PF09789.9 KXH52270.1 - 3.7e-06 26.5 26.3 3.7e-06 26.5 26.3 5.0 3 2 2 5 5 5 2 Uncharacterized coiled-coil protein (DUF2353) TIP49 PF06068.13 KXH52272.1 - 2.4e-167 556.5 0.2 2.9e-167 556.2 0.2 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 KXH52272.1 - 9.5e-26 89.7 0.1 2.2e-25 88.5 0.1 1.7 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 KXH52272.1 - 8.8e-12 45.6 0.2 3.3e-07 30.8 0.1 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KXH52272.1 - 2.1e-09 37.3 0.1 1.1e-06 28.5 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KXH52272.1 - 0.00016 22.0 0.2 0.28 11.4 0.0 2.5 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KXH52272.1 - 0.00079 19.8 0.1 0.0064 16.9 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.6 KXH52272.1 - 0.0014 19.0 1.8 0.16 12.3 0.3 2.4 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KXH52272.1 - 0.0014 18.9 0.1 0.0033 17.7 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 KXH52272.1 - 0.0073 15.9 0.2 0.048 13.2 0.1 2.1 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KXH52272.1 - 0.0077 16.2 0.1 0.21 11.6 0.1 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 KXH52272.1 - 0.01 16.4 0.0 0.028 14.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KXH52272.1 - 0.017 14.5 0.2 0.51 9.7 0.1 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 KXH52272.1 - 0.025 13.9 0.2 0.066 12.5 0.1 1.7 2 0 0 2 2 2 0 Zeta toxin DnaB_C PF03796.15 KXH52272.1 - 0.032 13.6 0.0 0.068 12.5 0.0 1.5 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain Sigma54_activat PF00158.26 KXH52272.1 - 0.034 13.8 0.1 1.9 8.1 0.1 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain IstB_IS21 PF01695.17 KXH52272.1 - 0.05 13.3 0.2 0.12 12.2 0.2 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_7 PF12775.7 KXH52272.1 - 0.074 12.6 0.1 0.21 11.1 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF2075 PF09848.9 KXH52272.1 - 0.1 11.8 0.2 0.22 10.7 0.0 1.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_33 PF13671.6 KXH52272.1 - 0.16 12.1 0.0 0.48 10.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain EamA PF00892.20 KXH52273.1 - 7.5e-21 74.7 25.0 6.6e-11 42.5 3.3 2.1 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 KXH52273.1 - 0.0035 16.6 0.9 0.011 15.0 0.9 1.8 1 0 0 1 1 1 1 UAA transporter family Trp_oprn_chp PF09534.10 KXH52273.1 - 0.05 13.4 5.4 0.36 10.6 1.6 2.3 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF4381 PF14316.6 KXH52273.1 - 0.079 13.2 0.2 0.4 10.9 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) TFIID-18kDa PF02269.16 KXH52274.1 - 2.8e-18 65.7 0.0 4.3e-18 65.1 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.13 KXH52274.1 - 0.0001 22.2 0.0 0.00018 21.5 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated CBFD_NFYB_HMF PF00808.23 KXH52274.1 - 0.0037 17.5 0.8 0.017 15.4 0.0 2.2 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 KXH52274.1 - 0.0064 16.8 0.0 0.011 16.1 0.0 1.4 1 0 0 1 1 1 1 CENP-S protein Histone PF00125.24 KXH52274.1 - 0.039 14.3 0.3 0.094 13.1 0.0 1.7 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 DUF1242 PF06842.12 KXH52275.1 - 2.6e-14 52.7 0.3 3.8e-14 52.2 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) WBP-1 PF11669.8 KXH52275.1 - 0.061 14.0 0.2 0.11 13.2 0.1 1.5 2 0 0 2 2 2 0 WW domain-binding protein 1 Tcp11 PF05794.13 KXH52276.1 - 6.1e-105 351.9 0.0 9.7e-105 351.2 0.0 1.3 1 1 0 1 1 1 1 T-complex protein 11 DUF3584 PF12128.8 KXH52276.1 - 0.084 10.4 0.0 0.13 9.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Uds1 PF15456.6 KXH52277.1 - 1.1e-39 135.6 9.4 1.1e-39 135.6 9.4 7.6 3 2 3 6 6 6 1 Up-regulated During Septation APG6_N PF17675.1 KXH52277.1 - 0.00017 22.1 4.1 0.00017 22.1 4.1 9.0 4 2 3 7 7 5 1 Apg6 coiled-coil region UPF0242 PF06785.11 KXH52277.1 - 0.00054 20.1 3.1 0.00054 20.1 3.1 7.0 5 2 1 7 7 7 2 Uncharacterised protein family (UPF0242) N-terminus HR1 PF02185.16 KXH52277.1 - 0.00079 19.5 6.3 0.00079 19.5 6.3 10.8 6 3 6 12 12 9 2 Hr1 repeat ATG16 PF08614.11 KXH52277.1 - 0.0021 18.3 24.2 0.0021 18.3 24.2 7.5 5 2 2 7 7 5 2 Autophagy protein 16 (ATG16) Rab5-bind PF09311.11 KXH52277.1 - 0.0043 16.5 11.3 0.0043 16.5 11.3 6.9 5 1 2 7 7 6 1 Rabaptin-like protein Fez1 PF06818.15 KXH52277.1 - 0.0072 16.8 22.7 0.0072 16.8 22.7 6.7 2 1 3 6 6 4 2 Fez1 TMF_DNA_bd PF12329.8 KXH52277.1 - 0.014 15.4 5.7 0.014 15.4 5.7 11.5 7 2 4 12 12 10 0 TATA element modulatory factor 1 DNA binding Leu_zip PF15294.6 KXH52277.1 - 0.016 14.7 0.9 0.016 14.7 0.9 6.2 4 1 2 6 6 6 0 Leucine zipper MOSC PF03473.17 KXH52277.1 - 0.034 14.2 0.6 0.56 10.2 0.1 2.9 2 0 0 2 2 2 0 MOSC domain TPK_catalytic PF04263.16 KXH52277.1 - 0.068 13.2 0.0 0.3 11.1 0.0 2.1 1 0 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain Peptidase_S66C PF17676.1 KXH52282.1 - 4.6e-26 91.8 0.0 5.4e-26 91.5 0.0 1.1 1 0 0 1 1 1 1 LD-carboxypeptidase C-terminal domain Pkinase PF00069.25 KXH52283.1 - 1.7e-67 227.6 0.0 3.1e-67 226.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXH52283.1 - 2.9e-37 128.3 0.0 5.4e-37 127.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXH52283.1 - 2.9e-05 23.5 0.0 5.9e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like NOG1_N PF17835.1 KXH52283.1 - 0.0048 16.9 4.3 0.011 15.7 0.2 3.1 3 0 0 3 3 3 1 NOG1 N-terminal helical domain Pkinase_fungal PF17667.1 KXH52283.1 - 0.0065 15.3 0.0 0.014 14.2 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KXH52283.1 - 0.012 15.6 0.0 0.042 13.8 0.0 1.9 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KXH52283.1 - 0.069 12.2 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Syntaxin-6_N PF09177.11 KXH52283.1 - 0.22 12.1 0.1 0.22 12.1 0.1 2.8 3 0 0 3 3 3 0 Syntaxin 6, N-terminal GCV_T PF01571.21 KXH52284.1 - 1.2e-75 254.2 0.0 1.5e-75 253.9 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 KXH52284.1 - 1.4e-22 79.4 0.4 3e-22 78.4 0.4 1.5 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain Rhomboid PF01694.22 KXH52285.1 - 3.9e-15 56.2 9.6 3.9e-15 56.2 9.6 1.9 2 0 0 2 2 2 1 Rhomboid family Aconitase PF00330.20 KXH52286.1 - 4.1e-150 500.8 0.0 5.2e-150 500.5 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KXH52286.1 - 1.1e-42 145.5 0.0 1.9e-42 144.7 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Sdh5 PF03937.16 KXH52286.1 - 0.22 11.5 0.0 0.45 10.5 0.0 1.4 1 0 0 1 1 1 0 Flavinator of succinate dehydrogenase Metallophos PF00149.28 KXH52287.1 - 7.7e-10 39.6 0.9 1.3e-09 38.9 0.9 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DNA_pol_phi PF04931.13 KXH52287.1 - 0.36 8.9 27.2 0.62 8.1 27.2 1.4 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 KXH52287.1 - 1.1 8.5 18.4 2.7 7.2 18.4 1.7 1 0 0 1 1 1 0 NOA36 protein DUF913 PF06025.12 KXH52287.1 - 4.3 6.2 5.1 8.7 5.2 5.1 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Nop14 PF04147.12 KXH52287.1 - 5.8 5.0 29.8 0.046 11.9 21.3 1.7 2 0 0 2 2 2 0 Nop14-like family SDA1 PF05285.12 KXH52287.1 - 6.8 6.0 36.0 0.009 15.5 20.9 2.3 2 1 0 2 2 2 0 SDA1 Pes-10 PF07149.11 KXH52287.1 - 8.6 5.3 13.5 14 4.6 13.5 1.2 1 0 0 1 1 1 0 Pes-10 Ofd1_CTDD PF10637.9 KXH52288.1 - 1.5e-96 322.7 0.0 4e-91 304.9 0.1 2.2 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 KXH52288.1 - 5e-25 88.0 0.0 2.1e-24 86.0 0.0 2.1 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 KXH52288.1 - 3.1e-12 47.2 0.0 6.6e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Aminotran_5 PF00266.19 KXH52289.1 - 2.8e-52 177.9 0.0 4.4e-52 177.3 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 KXH52289.1 - 1.3e-05 23.9 0.1 0.00043 18.9 0.0 2.2 1 1 1 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme Ribul_P_3_epim PF00834.19 KXH52290.1 - 6.3e-59 198.7 0.0 3.3e-58 196.4 0.0 1.9 1 1 0 1 1 1 1 Ribulose-phosphate 3 epimerase family ThiG PF05690.14 KXH52290.1 - 0.015 14.6 0.1 0.021 14.2 0.1 1.2 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG OMPdecase PF00215.24 KXH52290.1 - 0.078 12.6 0.4 0.14 11.7 0.1 1.5 2 0 0 2 2 2 0 Orotidine 5'-phosphate decarboxylase / HUMPS family QRPTase_C PF01729.19 KXH52290.1 - 0.12 12.2 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain V-ATPase_H_N PF03224.14 KXH52291.1 - 3.1e-76 256.7 0.0 4.2e-76 256.2 0.0 1.2 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 KXH52291.1 - 9.8e-36 122.4 0.0 4.3e-35 120.4 0.0 2.1 2 0 0 2 2 2 1 V-ATPase subunit H DUF4690 PF15756.5 KXH52292.1 - 2.2 8.9 6.6 0.82 10.3 1.6 2.7 3 0 0 3 3 3 0 Small Novel Rich in Cartilage LEP503 PF15221.6 KXH52292.1 - 5.8 7.3 7.6 0.76 10.1 1.5 2.3 2 0 0 2 2 2 0 Lens epithelial cell protein LEP503 Ribosomal_L6 PF00347.23 KXH52293.1 - 1.1e-26 93.3 7.5 9.4e-14 51.9 3.3 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 Vps26 PF03643.15 KXH52294.1 - 2.4e-130 433.5 0.9 2.9e-130 433.2 0.9 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 KXH52294.1 - 0.0002 21.4 0.5 0.47 10.5 0.0 3.6 2 1 2 4 4 4 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 KXH52294.1 - 0.0033 17.9 0.0 0.034 14.6 0.0 2.4 1 1 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain IL17R_D_N PF16742.5 KXH52294.1 - 0.068 13.2 0.1 0.15 12.1 0.1 1.5 1 0 0 1 1 1 0 N-terminus of interleukin 17 receptor D DUF3586 PF12131.8 KXH52314.1 - 0.011 15.9 0.2 0.017 15.3 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3586) DUF2613 PF11021.8 KXH52314.1 - 0.1 12.7 0.1 0.14 12.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) Methyltransf_16 PF10294.9 KXH52315.1 - 1.1e-16 61.1 0.0 1.7e-16 60.5 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_12 PF08242.12 KXH52315.1 - 0.0022 18.7 0.0 0.0047 17.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXH52315.1 - 0.0024 17.7 0.0 0.022 14.6 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH52315.1 - 0.01 16.5 0.0 0.026 15.2 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 KXH52315.1 - 0.04 13.5 0.0 0.089 12.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Chromo PF00385.24 KXH52316.1 - 0.028 14.3 0.0 0.053 13.4 0.0 1.4 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Suf PF05843.14 KXH52316.1 - 3.7 7.4 6.3 5.5 6.9 6.3 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Asparaginase PF00710.20 KXH52317.1 - 3.6e-43 147.3 0.0 5.2e-43 146.8 0.0 1.2 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 KXH52317.1 - 1.3e-14 54.3 0.2 3.1e-14 53.2 0.0 1.7 2 0 0 2 2 2 1 Glutaminase/Asparaginase C-terminal domain GDYXXLXY PF14345.6 KXH52318.1 - 0.091 12.6 0.0 1.3 8.8 0.0 2.1 2 0 0 2 2 2 0 GDYXXLXY protein DUF3328 PF11807.8 KXH52320.1 - 4.1e-16 59.4 1.8 1.1e-15 58.0 1.8 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) DUF5633 PF18656.1 KXH52321.1 - 1.1 9.2 3.8 11 6.1 0.2 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5633) MFS_1 PF07690.16 KXH52323.1 - 1.2e-28 100.1 23.8 1.2e-28 100.1 23.8 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF4338 PF14236.6 KXH52323.1 - 0.2 10.9 0.0 0.34 10.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4338) DUF3237 PF11578.8 KXH52324.1 - 1.9e-30 105.7 0.0 2.2e-30 105.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) Amidase PF01425.21 KXH52325.1 - 1.8e-82 277.7 0.0 7.9e-82 275.6 0.0 1.7 1 1 0 1 1 1 1 Amidase HTH_Tnp_Tc5 PF03221.16 KXH52326.1 - 5.3e-08 32.8 1.3 7.5e-08 32.3 0.1 1.9 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain zf-C2H2_4 PF13894.6 KXH52326.1 - 0.0084 16.9 4.8 0.0084 16.9 4.8 4.6 5 0 0 5 5 5 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KXH52326.1 - 0.16 12.5 19.2 1.5 9.5 0.1 4.1 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_3rep PF18868.1 KXH52326.1 - 0.61 10.8 3.4 1.3 9.8 0.1 2.9 2 1 1 3 3 3 0 Zinc finger C2H2-type, 3 repeats zf-H2C2_2 PF13465.6 KXH52326.1 - 8.8 7.0 11.9 7 7.3 5.0 3.5 3 0 0 3 3 3 0 Zinc-finger double domain CBM_1 PF00734.18 KXH52329.1 - 2.2e-12 46.7 10.2 7.7e-12 45.0 10.2 2.0 1 0 0 1 1 1 1 Fungal cellulose binding domain Nucleos_tra2_C PF07662.13 KXH52330.1 - 5.3e-69 232.2 1.9 5.3e-69 232.2 1.9 2.4 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 KXH52330.1 - 9.7e-25 87.0 1.0 9.7e-25 87.0 1.0 2.7 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter N-terminus COX2-transmemb PF09125.10 KXH52330.1 - 0.25 11.2 1.8 5.6 6.8 0.3 3.1 2 0 0 2 2 2 0 Cytochrome C oxidase subunit II, transmembrane Gate PF07670.14 KXH52330.1 - 0.72 10.2 18.9 0.09 13.0 8.1 3.6 3 1 0 3 3 3 0 Nucleoside recognition XdhC_C PF13478.6 KXH52331.1 - 0.16 12.5 0.0 0.23 12.0 0.0 1.2 1 0 0 1 1 1 0 XdhC Rossmann domain Sugar_tr PF00083.24 KXH52332.1 - 9.8e-71 238.9 28.8 1.1e-70 238.7 28.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH52332.1 - 7.8e-22 77.7 35.9 1.2e-20 73.8 32.9 2.7 2 1 1 3 3 3 1 Major Facilitator Superfamily MFS_2 PF13347.6 KXH52332.1 - 9.7e-06 24.4 1.6 9.7e-06 24.4 1.6 4.0 4 1 1 5 5 5 3 MFS/sugar transport protein Bac_rhamnosid6H PF17389.2 KXH52333.1 - 2.7e-17 63.1 0.0 6.4e-17 61.8 0.0 1.5 1 1 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Glyco_hydro_28 PF00295.17 KXH52334.1 - 3e-28 98.8 14.5 3.8e-28 98.5 12.5 1.8 1 1 1 2 2 2 2 Glycosyl hydrolases family 28 XRN_N PF03159.18 KXH52335.1 - 0.007 15.8 0.0 32 3.8 0.0 4.6 2 1 0 3 3 3 2 XRN 5'-3' exonuclease N-terminus SHR-BD PF06650.12 KXH52336.1 - 3.8e-97 324.9 0.0 4.1e-95 318.2 0.0 3.3 3 0 0 3 3 3 1 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13_mid_rpt PF16910.5 KXH52336.1 - 3.5e-91 304.8 2.0 1.3e-90 303.0 1.8 6.0 8 1 1 9 9 9 2 Repeating coiled region of VPS13 VPS13 PF16908.5 KXH52336.1 - 9.5e-87 290.7 0.9 8e-83 277.8 0.0 4.1 4 0 0 4 4 4 2 Vacuolar sorting-associated protein 13, N-terminal VPS13_C PF16909.5 KXH52336.1 - 2.5e-75 252.2 6.7 1.5e-70 236.6 0.5 2.8 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal Chorein_N PF12624.7 KXH52336.1 - 4.7e-40 136.3 1.0 1.7e-39 134.5 0.0 2.6 2 0 0 2 2 2 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 KXH52336.1 - 1.4e-08 35.0 0.1 1.4e-07 31.8 0.0 2.8 3 0 0 3 3 3 1 Autophagy-related protein C terminal domain DUF3429 PF11911.8 KXH52338.1 - 2.4e-45 154.3 8.1 3.2e-45 154.0 8.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) XPG_I PF00867.18 KXH52339.1 - 0.1 13.0 0.0 0.13 12.6 0.0 1.3 1 1 0 1 1 1 0 XPG I-region SelP_N PF04592.14 KXH52339.1 - 3.2 7.1 12.5 3.7 6.9 12.5 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region TauD PF02668.16 KXH52341.1 - 3.1e-53 181.3 0.4 3.6e-53 181.1 0.4 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Sld5 PF05916.11 KXH52342.1 - 1.6e-18 67.1 0.0 2.7e-18 66.4 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein Sod_Fe_C PF02777.18 KXH52343.1 - 1.1e-38 131.5 0.1 2.2e-38 130.5 0.1 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 KXH52343.1 - 5.2e-30 103.8 1.6 8.9e-30 103.0 1.6 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain HET PF06985.11 KXH52345.1 - 5.6e-26 91.6 0.1 9e-26 91.0 0.1 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) bZIP_1 PF00170.21 KXH52347.1 - 4.4e-09 36.3 7.4 7.2e-09 35.6 7.4 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 KXH52347.1 - 0.02 15.4 2.8 0.02 15.4 2.8 2.2 2 0 0 2 2 2 0 bZIP Maf transcription factor bZIP_2 PF07716.15 KXH52347.1 - 0.12 12.5 11.3 0.67 10.1 11.3 2.3 1 1 0 1 1 1 0 Basic region leucine zipper FAD_binding_4 PF01565.23 KXH52348.1 - 1.5e-30 105.7 0.2 3.7e-30 104.5 0.2 1.7 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 KXH52348.1 - 8e-07 29.1 0.0 2.1e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like Fungal_trans_2 PF11951.8 KXH52349.1 - 1.2e-07 30.9 1.1 2.7e-05 23.1 0.1 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain adh_short PF00106.25 KXH52350.1 - 4.6e-19 68.6 0.0 9.3e-15 54.6 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXH52350.1 - 4.7e-08 32.9 0.0 1.5e-06 28.0 0.0 2.1 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH52350.1 - 1.8e-06 28.0 0.0 3e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 KR domain OPT PF03169.15 KXH52352.1 - 1.3e-178 595.5 52.5 1.5e-178 595.3 52.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein AA_permease PF00324.21 KXH52353.1 - 1.5e-144 482.2 38.6 1.9e-144 481.9 38.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KXH52353.1 - 1.6e-39 135.9 40.9 2.2e-39 135.5 40.9 1.1 1 0 0 1 1 1 1 Amino acid permease zf-C2H2 PF00096.26 KXH52354.1 - 0.03 14.8 0.1 0.066 13.7 0.1 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXH52354.1 - 0.047 14.5 2.6 0.059 14.2 0.2 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger adh_short PF00106.25 KXH52355.1 - 2.4e-19 69.6 0.0 4.6e-18 65.4 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXH52355.1 - 1e-08 35.0 0.0 2.2e-08 34.0 0.0 1.4 1 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH52355.1 - 4.2e-06 26.8 0.0 9e-06 25.7 0.0 1.5 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KXH52355.1 - 0.00036 20.1 0.0 0.00057 19.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KXH52355.1 - 0.006 15.8 0.0 0.009 15.2 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KXH52355.1 - 0.023 14.1 0.0 0.034 13.5 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KXH52355.1 - 0.024 13.8 0.0 0.05 12.8 0.0 1.6 2 0 0 2 2 2 0 Male sterility protein Shikimate_DH PF01488.20 KXH52355.1 - 0.21 11.6 0.0 0.35 10.9 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF3425 PF11905.8 KXH52356.1 - 7.1e-18 64.8 0.0 1.5e-17 63.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 KXH52356.1 - 0.039 14.1 3.9 0.08 13.1 3.9 1.4 1 0 0 1 1 1 0 bZIP transcription factor NmrA PF05368.13 KXH52357.1 - 7.6e-22 78.0 0.0 9.5e-22 77.7 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXH52357.1 - 3.2e-07 30.4 0.0 4.5e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KXH52357.1 - 9.7e-05 21.9 0.0 0.00048 19.7 0.0 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KXH52357.1 - 0.13 12.2 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 KR domain Methyltransf_2 PF00891.18 KXH52358.1 - 1.7e-17 63.4 0.0 7.3e-17 61.4 0.0 2.0 2 1 0 2 2 2 1 O-methyltransferase domain Arginase PF00491.21 KXH52359.1 - 3.2e-23 82.6 0.0 3.6e-23 82.4 0.0 1.0 1 0 0 1 1 1 1 Arginase family Condensation PF00668.20 KXH52360.1 - 5.1e-85 285.8 0.0 2.3e-31 109.0 0.0 3.6 3 1 0 3 3 3 3 Condensation domain AMP-binding PF00501.28 KXH52360.1 - 5.8e-33 114.1 0.0 1.1e-32 113.2 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 KXH52360.1 - 8.6e-17 61.3 0.1 2.1e-05 24.8 0.0 4.8 4 0 0 4 4 4 3 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KXH52360.1 - 0.05 14.6 0.0 2 9.5 0.0 3.0 3 0 0 3 3 3 0 AMP-binding enzyme C-terminal domain Transferase PF02458.15 KXH52360.1 - 0.15 10.7 0.0 14 4.2 0.0 2.3 2 0 0 2 2 2 0 Transferase family Abhydrolase_3 PF07859.13 KXH52361.1 - 1.8e-29 103.1 0.0 4.2e-29 101.9 0.0 1.6 1 1 1 2 2 2 1 alpha/beta hydrolase fold COesterase PF00135.28 KXH52361.1 - 0.0091 14.9 0.0 0.013 14.4 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_2 PF02230.16 KXH52361.1 - 0.012 15.4 0.0 0.019 14.8 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Say1_Mug180 PF10340.9 KXH52361.1 - 0.025 13.5 0.0 0.2 10.5 0.0 1.9 2 0 0 2 2 2 0 Steryl acetyl hydrolase DNA_pol_phi PF04931.13 KXH52362.1 - 0.004 15.3 15.3 0.004 15.3 15.3 1.6 2 0 0 2 2 2 1 DNA polymerase phi Mito_fiss_reg PF05308.11 KXH52362.1 - 0.0088 16.1 2.3 0.014 15.4 2.3 1.2 1 0 0 1 1 1 1 Mitochondrial fission regulator CAP_N PF01213.19 KXH52362.1 - 0.3 10.5 4.4 0.46 9.9 4.4 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal NeA_P2 PF12312.8 KXH52362.1 - 0.71 9.3 4.1 1.1 8.7 4.1 1.2 1 0 0 1 1 1 0 Nepovirus subgroup A polyprotein DUF4690 PF15756.5 KXH52362.1 - 1 10.0 2.9 1.2 9.8 0.3 2.2 2 0 0 2 2 2 0 Small Novel Rich in Cartilage PRIMA1 PF16101.5 KXH52362.1 - 3.3 7.8 7.8 6.2 6.9 7.8 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 SAPS PF04499.15 KXH52363.1 - 4e-192 639.3 0.0 6.6e-191 635.3 0.0 2.7 2 1 0 2 2 2 1 SIT4 phosphatase-associated protein Epimerase PF01370.21 KXH52365.1 - 1e-11 44.8 0.0 2.6e-11 43.4 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXH52365.1 - 5.1e-11 42.1 0.0 1e-10 41.1 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KXH52365.1 - 1.9e-08 34.4 0.0 2.8e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KXH52365.1 - 2.2e-08 33.9 0.0 5.9e-08 32.5 0.0 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 KXH52365.1 - 1.8e-07 30.9 0.0 2.8e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.12 KXH52365.1 - 8.1e-07 28.5 0.0 8.8e-05 21.8 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.15 KXH52365.1 - 0.013 14.7 0.0 0.021 14.0 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein GCFC PF07842.12 KXH52366.1 - 3e-68 230.4 3.5 6.1e-68 229.4 3.5 1.5 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.23 KXH52366.1 - 3.4e-15 55.6 2.4 8.8e-15 54.3 2.4 1.8 1 0 0 1 1 1 1 G-patch domain TIP_N PF12457.8 KXH52366.1 - 2e-13 50.6 14.9 2e-13 50.6 14.9 3.2 3 1 0 3 3 3 1 Tuftelin interacting protein N terminal G-patch_2 PF12656.7 KXH52366.1 - 1.3e-07 31.6 1.3 1.3e-07 31.6 1.3 2.5 2 0 0 2 2 2 1 G-patch domain ATP-synt_E PF05680.12 KXH52366.1 - 2 8.8 7.4 8.8 6.8 7.4 2.1 1 0 0 1 1 1 0 ATP synthase E chain Atrophin-1 PF03154.15 KXH52366.1 - 2.5 6.3 7.5 4.5 5.4 7.5 1.3 1 0 0 1 1 1 0 Atrophin-1 family Cyt-b5 PF00173.28 KXH52367.1 - 2.6e-15 56.3 0.0 7.4e-15 54.9 0.0 1.8 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FAD_binding_1 PF00667.20 KXH52367.1 - 3e-09 36.8 0.0 1.8e-08 34.2 0.0 2.2 1 1 0 1 1 1 1 FAD binding domain IDO PF01231.18 KXH52367.1 - 3.3e-09 36.0 0.0 2.3e-08 33.2 0.0 2.2 2 0 0 2 2 2 1 Indoleamine 2,3-dioxygenase NAD_binding_1 PF00175.21 KXH52367.1 - 3.4e-08 34.1 0.0 8.4e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain zf-LITAF-like PF10601.9 KXH52368.1 - 2e-18 66.4 1.4 2.8e-18 65.9 1.4 1.1 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain WD40 PF00400.32 KXH52369.1 - 8.4e-51 168.9 17.2 2e-08 34.8 0.5 8.6 8 1 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXH52369.1 - 1.4e-10 41.4 0.1 0.0021 18.3 0.0 4.4 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KXH52369.1 - 1.1e-08 34.2 0.0 0.00069 18.4 0.0 4.2 5 0 0 5 5 5 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 KXH52369.1 - 3.5e-05 22.7 0.0 0.063 12.0 0.0 3.1 3 0 0 3 3 3 2 Nup133 N terminal like Kelch_4 PF13418.6 KXH52377.1 - 1.3e-17 63.6 0.1 2e-06 27.7 0.0 4.7 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_3 PF13415.6 KXH52377.1 - 7.4e-14 51.6 7.9 4.5e-08 33.2 0.0 6.2 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_6 PF13964.6 KXH52377.1 - 7.7e-14 51.4 4.0 0.00032 20.9 0.9 4.8 3 1 1 4 4 4 3 Kelch motif Kelch_1 PF01344.25 KXH52377.1 - 1.5e-13 50.1 0.1 0.0012 18.4 0.0 4.6 4 0 0 4 4 4 3 Kelch motif Kelch_5 PF13854.6 KXH52377.1 - 1e-12 47.8 1.7 4.4e-05 23.4 0.1 4.0 3 0 0 3 3 3 2 Kelch motif Kelch_2 PF07646.15 KXH52377.1 - 2.9e-08 33.4 0.2 0.00032 20.5 0.0 4.6 5 1 0 5 5 5 1 Kelch motif Tax PF02959.16 KXH52377.1 - 0.044 13.2 1.7 2.9 7.3 0.0 2.4 2 0 0 2 2 2 0 HTLV Tax BTB PF00651.31 KXH52377.1 - 0.064 13.5 0.0 0.31 11.3 0.0 2.0 2 0 0 2 2 2 0 BTB/POZ domain Myb_DNA-binding PF00249.31 KXH52379.1 - 3.3e-07 30.4 0.2 2.2e-06 27.7 0.0 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KXH52379.1 - 6.2e-05 23.2 0.1 0.00016 21.9 0.1 1.7 1 1 1 2 2 2 1 Myb-like DNA-binding domain Rap1_C PF11626.8 KXH52379.1 - 0.033 14.3 0.0 0.056 13.5 0.0 1.4 1 0 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain UbiA PF01040.18 KXH52380.1 - 9.8e-58 195.4 15.4 9.8e-58 195.4 15.4 1.5 1 1 0 1 1 1 1 UbiA prenyltransferase family AXE1 PF05448.12 KXH52381.1 - 0.13 10.9 0.1 0.24 10.0 0.1 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Abhydrolase_6 PF12697.7 KXH52382.1 - 2.2e-05 25.2 5.2 2.2e-05 25.2 5.2 2.0 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXH52382.1 - 0.027 14.1 0.0 0.046 13.4 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Ser_hydrolase PF06821.13 KXH52382.1 - 0.036 13.9 0.0 0.066 13.1 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase Abhydrolase_8 PF06259.12 KXH52382.1 - 0.058 13.0 0.1 0.26 10.9 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase Cupin_2 PF07883.11 KXH52383.1 - 5e-08 32.5 0.0 7.5e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.7 KXH52383.1 - 0.0034 17.1 0.0 0.0039 16.9 0.0 1.3 1 1 0 1 1 1 1 Cupin Cupin_1 PF00190.22 KXH52383.1 - 0.0091 15.6 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.12 KXH52383.1 - 0.1 12.3 0.0 0.18 11.5 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF861) DUF3506 PF12014.8 KXH52384.1 - 3.2e-58 195.7 0.0 4.8e-58 195.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3506) F-box-like PF12937.7 KXH52384.1 - 1.2e-05 25.1 0.8 2.6e-05 24.0 0.8 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXH52384.1 - 3.2e-05 23.7 0.1 6.1e-05 22.8 0.1 1.4 1 0 0 1 1 1 1 F-box domain CMAS PF02353.20 KXH52385.1 - 1.7e-17 63.6 0.2 1.2e-15 57.6 0.2 2.2 1 1 1 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.12 KXH52385.1 - 1.3e-16 61.0 0.1 6.7e-16 58.7 0.1 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH52385.1 - 5.2e-15 55.9 0.3 4.2e-13 49.8 0.3 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXH52385.1 - 2.6e-14 53.4 0.0 3.8e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH52385.1 - 1.6e-13 51.2 0.0 3.4e-13 50.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH52385.1 - 2.4e-12 46.9 0.1 4.1e-10 39.7 0.1 2.3 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXH52385.1 - 9.3e-06 25.1 0.1 7.6e-05 22.1 0.1 2.1 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MetW PF07021.12 KXH52385.1 - 0.00015 21.4 0.0 0.023 14.3 0.2 2.2 1 1 1 2 2 2 1 Methionine biosynthesis protein MetW MTS PF05175.14 KXH52385.1 - 0.00031 20.4 0.2 0.0045 16.6 0.2 2.2 2 0 0 2 2 2 1 Methyltransferase small domain FtsJ PF01728.19 KXH52385.1 - 0.00071 19.7 0.1 0.001 19.2 0.1 1.4 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_32 PF13679.6 KXH52385.1 - 0.0013 18.8 0.1 0.0022 18.0 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 KXH52385.1 - 0.008 15.7 0.1 0.013 15.0 0.1 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 PCMT PF01135.19 KXH52385.1 - 0.028 14.2 0.1 0.081 12.7 0.1 1.7 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_PK PF05891.12 KXH52385.1 - 0.03 13.8 0.0 0.32 10.5 0.0 2.1 1 1 0 1 1 1 0 AdoMet dependent proline di-methyltransferase TehB PF03848.14 KXH52385.1 - 0.053 12.9 0.1 0.12 11.8 0.0 1.5 2 0 0 2 2 2 0 Tellurite resistance protein TehB Peptidase_M50B PF13398.6 KXH52386.1 - 6.9e-60 202.1 18.8 8.7e-60 201.8 18.8 1.1 1 0 0 1 1 1 1 Peptidase M50B-like Peptidase_M50 PF02163.22 KXH52386.1 - 0.021 14.1 0.2 0.051 12.8 0.0 1.7 2 0 0 2 2 2 0 Peptidase family M50 ACR_tran PF00873.19 KXH52386.1 - 0.056 11.1 0.4 0.086 10.5 0.4 1.3 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family DUF4360 PF14273.6 KXH52387.1 - 1.9e-23 83.3 0.6 3.3e-23 82.5 0.6 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4360) MFS_1 PF07690.16 KXH52388.1 - 0.0038 16.2 8.3 0.018 14.0 8.2 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily MutS_V PF00488.21 KXH52389.1 - 5.6e-66 222.2 1.2 7.6e-66 221.7 0.3 1.7 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.18 KXH52389.1 - 1.1e-42 146.4 0.1 2.5e-42 145.3 0.1 1.6 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 KXH52389.1 - 3e-33 114.4 0.0 7.1e-33 113.2 0.0 1.7 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 KXH52389.1 - 3.1e-14 53.4 0.0 1e-13 51.7 0.0 1.9 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 KXH52389.1 - 8e-13 48.6 0.7 2.4e-12 47.0 0.7 1.9 1 0 0 1 1 1 1 MutS family domain IV AAA_23 PF13476.6 KXH52389.1 - 0.0011 19.6 3.6 0.0032 18.0 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_27 PF13514.6 KXH52389.1 - 0.04 13.5 0.0 0.1 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.6 KXH52389.1 - 0.043 13.6 0.2 0.14 11.9 0.2 1.9 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KXH52389.1 - 0.094 12.5 0.0 0.28 10.9 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain MFS_1 PF07690.16 KXH52390.1 - 2e-39 135.6 19.0 2e-39 135.6 19.0 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH52390.1 - 1.7e-09 37.1 7.0 1.7e-09 37.1 7.0 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KXH52390.1 - 3.2e-06 25.9 4.4 4.6e-06 25.3 4.4 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) TMEM154 PF15102.6 KXH52391.1 - 0.0083 16.0 1.3 0.016 15.1 1.3 1.5 1 1 0 1 1 1 1 TMEM154 protein family DUF2543 PF10820.8 KXH52391.1 - 0.023 14.8 0.1 0.038 14.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2543) Rax2 PF12768.7 KXH52391.1 - 0.027 13.9 0.1 0.036 13.5 0.1 1.1 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Polysacc_synt_4 PF04669.13 KXH52392.1 - 5.8e-22 78.2 1.4 2.5e-20 72.8 1.4 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis AChE_tetra PF08674.10 KXH52392.1 - 0.86 9.3 5.2 0.58 9.9 2.7 2.0 2 0 0 2 2 2 0 Acetylcholinesterase tetramerisation domain MFS_1 PF07690.16 KXH52394.1 - 4.5e-45 154.1 35.3 4.5e-45 154.1 35.3 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH52394.1 - 1.4e-09 37.3 8.2 1.4e-09 37.3 8.2 2.9 3 0 0 3 3 3 1 Sugar (and other) transporter PK PF00224.21 KXH52395.1 - 1.5e-164 547.0 4.9 1.1e-162 540.8 4.9 2.1 1 1 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 KXH52395.1 - 5e-37 126.7 0.0 1.3e-36 125.3 0.0 1.8 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 KXH52395.1 - 0.00054 19.2 0.5 0.0021 17.3 0.2 2.0 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.25 KXH52395.1 - 0.017 14.1 0.1 0.29 10.1 0.0 2.1 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain DUF1748 PF08520.10 KXH52396.1 - 7e-32 109.1 0.0 8.6e-32 108.9 0.0 1.1 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) Seryl_tRNA_N PF02403.22 KXH52397.1 - 0.037 14.3 0.5 0.037 14.3 0.5 2.8 3 1 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Filament PF00038.21 KXH52397.1 - 0.055 13.1 3.9 0.3 10.6 0.1 2.6 2 1 0 2 2 2 0 Intermediate filament protein KELK PF15796.5 KXH52397.1 - 0.14 12.6 2.9 0.25 11.8 0.2 2.5 2 0 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Spc7 PF08317.11 KXH52397.1 - 0.83 8.5 12.4 0.034 13.0 0.8 2.7 3 1 0 3 3 3 0 Spc7 kinetochore protein GAS PF13851.6 KXH52397.1 - 1.1 8.5 5.0 3.5 6.9 0.6 2.6 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding CCDC-167 PF15188.6 KXH52397.1 - 2.3 8.6 5.2 6.2 7.2 0.3 2.9 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 ZapB PF06005.12 KXH52397.1 - 3.3 8.2 9.8 4.6 7.7 1.5 3.3 3 0 0 3 3 3 0 Cell division protein ZapB FlgN PF05130.12 KXH52397.1 - 3.4 8.2 12.8 6.7 7.2 2.2 3.0 3 0 0 3 3 3 0 FlgN protein WD40 PF00400.32 KXH52398.1 - 3.1e-11 43.6 5.7 0.00048 20.9 0.0 5.1 4 0 0 4 4 4 3 WD domain, G-beta repeat ADH_zinc_N PF00107.26 KXH52399.1 - 1.5e-26 92.9 0.2 2.8e-26 92.0 0.0 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXH52399.1 - 2.1e-13 51.5 0.0 3.1e-13 50.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXH52399.1 - 4e-06 26.7 0.0 2.1e-05 24.4 0.0 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Spt5-NGN PF03439.13 KXH52400.1 - 5.6e-25 87.1 0.0 9.2e-25 86.4 0.0 1.4 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.8 KXH52400.1 - 1.2e-21 77.5 10.0 1.2e-21 77.5 10.0 3.3 3 0 0 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal CTD PF12815.7 KXH52400.1 - 2.4e-21 76.1 35.6 4.4e-19 68.8 18.6 4.3 1 1 2 3 3 3 2 Spt5 C-terminal nonapeptide repeat binding Spt4 KOW PF00467.29 KXH52400.1 - 2.5e-05 24.1 20.5 0.0002 21.2 0.4 5.3 6 0 0 6 6 6 2 KOW motif Cornifin PF02389.15 KXH52400.1 - 0.0028 17.9 1.4 0.0066 16.7 1.4 1.6 1 0 0 1 1 1 1 Cornifin (SPRR) family Oxidored_molyb PF00174.19 KXH52401.1 - 1.3e-56 190.9 0.0 2e-56 190.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 KXH52401.1 - 3.3e-26 92.0 0.1 6.8e-26 90.9 0.1 1.6 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Cyt-b5 PF00173.28 KXH52401.1 - 8.1e-11 41.9 0.0 1.7e-10 40.9 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain zf-C2H2_aberr PF17017.5 KXH52401.1 - 0.025 14.7 1.8 13 5.9 0.4 3.3 3 0 0 3 3 3 0 Aberrant zinc-finger CDC45 PF02724.14 KXH52401.1 - 2.9 6.1 11.0 5.3 5.2 11.0 1.4 1 0 0 1 1 1 0 CDC45-like protein mRNA_triPase PF02940.15 KXH52402.1 - 2.9e-56 190.7 0.0 4e-56 190.2 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain RPN2_C PF18004.1 KXH52403.1 - 3.3e-58 196.1 4.0 3.3e-58 196.1 4.0 1.8 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 KXH52403.1 - 3.1e-40 134.6 23.7 1.1e-08 35.0 0.0 9.1 9 0 0 9 9 9 7 Proteasome/cyclosome repeat HEAT_2 PF13646.6 KXH52403.1 - 5.4e-21 74.8 0.0 2.7e-14 53.3 0.0 5.6 3 1 2 5 5 5 2 HEAT repeats HEAT PF02985.22 KXH52403.1 - 1e-06 28.5 0.8 2.9 8.4 0.0 6.4 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.6 KXH52403.1 - 9.1e-05 22.9 0.1 0.019 15.4 0.0 4.7 3 1 1 4 4 4 2 HEAT-like repeat Cnd1 PF12717.7 KXH52403.1 - 0.0038 17.3 0.2 2.5 8.1 0.0 3.3 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 TPR_19 PF14559.6 KXH52403.1 - 0.059 13.9 0.9 22 5.6 1.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TAL_FSA PF00923.19 KXH52404.1 - 3.1e-45 154.7 0.0 3.7e-45 154.5 0.0 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase WbqC PF08889.11 KXH52404.1 - 0.035 14.0 0.0 0.061 13.2 0.0 1.4 1 0 0 1 1 1 0 WbqC-like protein family AA_permease_2 PF13520.6 KXH52405.1 - 2.7e-62 211.0 29.2 6.8e-62 209.7 27.3 2.5 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXH52405.1 - 5.9e-12 44.9 19.6 5.9e-12 44.9 19.6 3.2 2 2 1 3 3 3 1 Amino acid permease Xan_ur_permease PF00860.20 KXH52407.1 - 1.5e-62 211.6 34.1 1.5e-61 208.3 34.1 2.0 1 1 0 1 1 1 1 Permease family Transp_cyt_pur PF02133.15 KXH52408.1 - 7.3e-93 311.7 35.4 8.4e-93 311.5 35.4 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Shikimate_dh_N PF08501.11 KXH52409.1 - 2.3e-22 79.0 0.0 6.7e-22 77.5 0.0 1.9 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain DHquinase_I PF01487.15 KXH52409.1 - 2.8e-21 76.8 0.0 4.7e-21 76.1 0.0 1.3 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.22 KXH52409.1 - 4.3e-10 39.9 0.4 1e-09 38.7 0.1 1.7 2 0 0 2 2 2 1 Shikimate kinase SDH_C PF18317.1 KXH52409.1 - 7.9e-09 35.1 0.2 1.6e-08 34.1 0.2 1.6 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 KXH52409.1 - 1.5e-06 28.3 0.1 3.2e-06 27.2 0.1 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase AAA_25 PF13481.6 KXH52409.1 - 0.00075 19.1 0.0 0.06 12.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain F420_oxidored PF03807.17 KXH52409.1 - 0.058 14.0 0.0 0.21 12.2 0.0 1.9 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Fungal_trans PF04082.18 KXH52410.1 - 0.0098 14.9 0.0 0.014 14.5 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF1688 PF07958.11 KXH52410.1 - 0.02 13.7 0.0 0.027 13.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1688) GA-like PF17573.2 KXH52410.1 - 0.068 13.1 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 GA-like domain Sugar_tr PF00083.24 KXH52411.1 - 1e-136 456.4 25.7 1.2e-136 456.2 25.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH52411.1 - 4e-23 81.9 35.7 4e-23 81.9 35.7 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Shikimate_dh_N PF08501.11 KXH52412.1 - 2.2e-21 75.9 0.0 4.5e-21 74.9 0.0 1.5 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 KXH52412.1 - 2.8e-06 27.0 0.0 6e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 KXH52412.1 - 0.013 15.6 0.0 0.023 14.7 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase AP_endonuc_2 PF01261.24 KXH52413.1 - 7.9e-34 116.9 0.1 1.2e-33 116.3 0.1 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Inositol_P PF00459.25 KXH52414.1 - 9.8e-80 267.9 0.0 1.1e-79 267.8 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Fe-ADH PF00465.19 KXH52415.1 - 1e-68 231.8 1.9 3.9e-68 229.9 1.9 1.7 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 KXH52415.1 - 3.7e-14 53.0 0.0 5.6e-14 52.4 0.0 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase ANAPC4_WD40 PF12894.7 KXH52416.1 - 3.5e-07 30.4 0.0 0.00074 19.8 0.0 3.3 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KXH52416.1 - 0.014 16.3 9.8 1.8 9.5 0.0 4.8 4 1 1 5 5 5 0 WD domain, G-beta repeat PQQ_3 PF13570.6 KXH52416.1 - 0.19 12.3 1.8 27 5.4 0.1 3.8 4 0 0 4 4 4 0 PQQ-like domain CDC45 PF02724.14 KXH52416.1 - 0.69 8.1 6.8 0.97 7.6 6.8 1.1 1 0 0 1 1 1 0 CDC45-like protein MFMR_assoc PF16596.5 KXH52416.1 - 1.3 9.5 9.4 0.86 10.1 6.7 2.1 2 0 0 2 2 2 0 Disordered region downstream of MFMR Cwf_Cwc_15 PF04889.12 KXH52416.1 - 3 7.5 9.6 4.7 6.9 9.6 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Pes-10 PF07149.11 KXH52416.1 - 3.1 6.8 3.4 4.4 6.3 3.4 1.1 1 0 0 1 1 1 0 Pes-10 Glyco_hydro_18 PF00704.28 KXH52417.1 - 8.7e-70 235.9 0.0 1e-69 235.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 GHL15 PF14885.6 KXH52417.1 - 8.8e-05 22.6 0.1 0.00016 21.7 0.1 1.4 1 0 0 1 1 1 1 Hypothetical glycosyl hydrolase family 15 Glyco_hydro_114 PF03537.13 KXH52417.1 - 0.14 11.4 0.1 0.2 10.9 0.1 1.2 1 0 0 1 1 1 0 Glycoside-hydrolase family GH114 MARVEL PF01284.23 KXH52418.1 - 4.1e-16 59.3 20.5 5.7e-16 58.8 20.5 1.2 1 0 0 1 1 1 1 Membrane-associating domain GDPD PF03009.17 KXH52419.1 - 1.2e-11 44.8 0.0 1.5e-11 44.5 0.0 1.2 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Diphthamide_syn PF01866.17 KXH52420.1 - 4e-88 295.8 0.0 4.9e-88 295.5 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein Dscam_C PF12355.8 KXH52420.1 - 1.2 10.1 6.1 0.29 12.1 0.7 2.4 3 0 0 3 3 3 0 Down syndrome cell adhesion molecule C terminal MARVEL PF01284.23 KXH52421.1 - 0.0014 18.7 15.7 0.002 18.2 15.7 1.2 1 0 0 1 1 1 1 Membrane-associating domain DUF4293 PF14126.6 KXH52421.1 - 0.0052 17.1 4.9 0.011 15.9 3.7 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4293) TspO_MBR PF03073.15 KXH52421.1 - 0.029 14.4 13.0 0.58 10.2 0.0 2.1 2 0 0 2 2 2 0 TspO/MBR family 7TMR-DISM_7TM PF07695.11 KXH52421.1 - 0.048 13.5 17.2 0.84 9.5 12.3 2.1 2 0 0 2 2 2 0 7TM diverse intracellular signalling Myc_target_1 PF15179.6 KXH52421.1 - 3.9 7.3 9.0 1.3 8.9 2.5 2.1 2 0 0 2 2 2 0 Myc target protein 1 Diphthami_syn_2 PF01902.17 KXH52455.1 - 9.1e-21 74.4 0.0 2.3e-16 60.0 0.0 3.5 3 1 0 3 3 3 3 Diphthamide synthase Ribonuc_L-PSP PF01042.21 KXH52455.1 - 2.1e-11 43.9 0.1 7e-08 32.5 0.0 3.5 3 1 0 3 3 3 2 Endoribonuclease L-PSP Acyl_transf_3 PF01757.22 KXH52456.1 - 1.7e-26 93.2 33.4 2.1e-26 92.8 33.4 1.1 1 0 0 1 1 1 1 Acyltransferase family DUF5487 PF17589.2 KXH52456.1 - 0.022 15.0 0.0 0.046 14.0 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5487) peroxidase PF00141.23 KXH52457.1 - 4.2e-19 69.1 0.3 8.2e-19 68.2 0.3 1.4 1 0 0 1 1 1 1 Peroxidase FAD_binding_3 PF01494.19 KXH52458.1 - 2.3e-74 250.7 0.0 2.8e-74 250.5 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 KXH52458.1 - 1.2e-30 106.7 0.0 2.5e-30 105.7 0.0 1.5 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox_2 PF07992.14 KXH52458.1 - 7.6e-08 31.9 0.0 0.00012 21.5 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXH52458.1 - 7e-05 21.7 0.4 0.00015 20.6 0.2 1.6 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 KXH52458.1 - 0.00013 22.4 0.0 0.018 15.6 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KXH52458.1 - 0.00083 18.5 0.1 0.0015 17.7 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 KXH52458.1 - 0.0012 19.1 0.1 0.0029 17.8 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXH52458.1 - 0.0045 16.6 0.1 0.35 10.4 0.0 2.2 1 1 1 2 2 2 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KXH52458.1 - 0.006 15.5 0.0 0.0093 14.9 0.0 1.2 1 0 0 1 1 1 1 Tryptophan halogenase GIDA PF01134.22 KXH52458.1 - 0.0093 15.1 0.0 0.015 14.4 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.17 KXH52458.1 - 0.03 13.5 0.0 0.051 12.8 0.0 1.2 1 0 0 1 1 1 0 Thi4 family AlaDh_PNT_C PF01262.21 KXH52458.1 - 0.031 13.6 0.0 0.053 12.8 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 KXH52458.1 - 0.23 10.7 0.1 0.37 10.0 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Peptidase_M3 PF01432.20 KXH52460.1 - 1e-120 404.1 0.0 1.4e-120 403.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.6 KXH52460.1 - 0.084 12.5 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Peptidase M50B-like ApoO PF09769.9 KXH52461.1 - 9.7e-43 145.2 0.3 1.2e-41 141.7 0.1 2.1 2 0 0 2 2 2 1 Apolipoprotein O Dus PF01207.17 KXH52462.1 - 5.5e-44 150.5 0.1 2.7e-43 148.2 0.1 1.8 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) PucR PF07905.11 KXH52462.1 - 0.08 13.2 0.1 0.3 11.4 0.0 1.9 1 1 0 1 1 1 0 Purine catabolism regulatory protein-like family Plus-3 PF03126.18 KXH52462.1 - 0.082 13.4 0.0 0.14 12.7 0.0 1.3 1 0 0 1 1 1 0 Plus-3 domain Pyrophosphatase PF00719.19 KXH52463.1 - 8e-58 194.8 0.1 1.1e-57 194.3 0.1 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase MRP_L53 PF10780.9 KXH52464.1 - 6.3e-21 74.3 0.4 8.8e-21 73.8 0.4 1.2 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 VioE PF18234.1 KXH52464.1 - 0.05 13.7 0.0 0.053 13.7 0.0 1.1 1 0 0 1 1 1 0 Violacein biosynthetic enzyme VioE DUF2442 PF10387.9 KXH52464.1 - 0.079 13.3 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2442) Sec20 PF03908.13 KXH52465.1 - 1.9e-13 50.2 2.6 3.9e-13 49.1 0.0 2.6 3 0 0 3 3 3 1 Sec20 ALMT PF11744.8 KXH52465.1 - 0.28 10.0 3.9 0.39 9.5 3.9 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter zf-Tim10_DDP PF02953.15 KXH52467.1 - 0.023 14.3 6.9 1 9.0 4.8 3.0 2 1 0 2 2 2 0 Tim10/DDP family zinc finger Aldolase_II PF00596.21 KXH52468.1 - 7e-41 140.2 0.0 8.9e-41 139.9 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Calreticulin PF00262.18 KXH52469.1 - 1.6e-169 563.6 19.0 2.4e-169 563.0 19.0 1.3 1 0 0 1 1 1 1 Calreticulin family DUF1911 PF08929.10 KXH52469.1 - 0.0099 16.7 0.3 0.06 14.2 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF1911) Aldedh PF00171.22 KXH52470.1 - 1.6e-132 442.3 0.3 2e-132 442.0 0.3 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KXH52470.1 - 0.091 11.8 0.1 0.21 10.6 0.0 1.6 2 0 0 2 2 2 0 Acyl-CoA reductase (LuxC) Voltage_CLC PF00654.20 KXH52517.1 - 2.5e-86 290.1 28.0 2.5e-86 290.1 28.0 1.4 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 KXH52517.1 - 0.00064 20.1 0.0 0.026 15.0 0.0 2.6 2 0 0 2 2 2 1 CBS domain LacI PF00356.21 KXH52517.1 - 0.39 10.6 1.8 1 9.2 1.8 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family Neurochondrin PF05536.11 KXH52518.1 - 7.3e-88 295.5 0.3 9e-88 295.2 0.3 1.0 1 0 0 1 1 1 1 Neurochondrin RIX1 PF08167.12 KXH52518.1 - 0.09 12.5 0.0 0.63 9.7 0.0 2.4 2 0 0 2 2 2 0 rRNA processing/ribosome biogenesis YqzE PF14038.6 KXH52519.1 - 0.032 14.2 1.7 0.032 14.2 1.7 2.1 2 0 0 2 2 2 0 YqzE-like protein DUF768 PF05589.11 KXH52519.1 - 0.17 11.9 2.5 0.21 11.6 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF768) Coilin_N PF15862.5 KXH52519.1 - 0.59 9.9 7.0 0.48 10.2 3.4 2.1 2 0 0 2 2 2 0 Coilin N-terminus THOC2_N PF16134.5 KXH52519.1 - 7.5 5.0 6.2 6 5.4 3.8 1.7 2 0 0 2 2 2 0 THO complex subunit 2 N-terminus Ras PF00071.22 KXH52521.1 - 1.3e-52 177.7 0.0 1.5e-52 177.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXH52521.1 - 5.4e-19 68.6 0.0 7.4e-19 68.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXH52521.1 - 1.3e-06 28.0 0.0 1.7e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Arginase PF00491.21 KXH52522.1 - 7.2e-89 298.0 0.0 2.2e-84 283.3 0.0 2.1 2 0 0 2 2 2 2 Arginase family UPF0489 PF12640.7 KXH52522.1 - 0.019 15.2 0.9 0.06 13.6 0.2 1.8 1 1 0 2 2 2 0 UPF0489 domain F-box-like PF12937.7 KXH52584.1 - 2.3e-06 27.4 0.3 5.5e-06 26.2 0.3 1.7 1 0 0 1 1 1 1 F-box-like Peroxidase_2 PF01328.17 KXH52585.1 - 9e-49 166.5 0.2 1.2e-48 166.2 0.2 1.0 1 0 0 1 1 1 1 Peroxidase, family 2 Vint PF14623.6 KXH52586.1 - 2.7e-65 219.2 0.0 4.5e-65 218.5 0.0 1.4 1 0 0 1 1 1 1 Hint-domain Vwaint PF14624.6 KXH52586.1 - 2.5e-29 101.2 0.0 4.5e-29 100.4 0.0 1.4 1 0 0 1 1 1 1 VWA / Hh protein intein-like VWA PF00092.28 KXH52586.1 - 3.6e-19 69.7 0.0 8.4e-19 68.5 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KXH52586.1 - 5e-13 49.6 0.0 1.2e-12 48.4 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 KXH52586.1 - 9.5e-12 45.1 0.0 1.7e-09 37.8 0.0 3.2 3 0 0 3 3 3 1 von Willebrand factor type A domain Hint PF01079.20 KXH52586.1 - 0.11 12.0 0.0 0.42 10.1 0.0 1.9 2 0 0 2 2 2 0 Hint module Hint_2 PF13403.6 KXH52586.1 - 0.13 12.5 0.0 0.33 11.2 0.0 1.7 1 1 0 1 1 1 0 Hint domain Fasciclin PF02469.22 KXH52587.1 - 2.3e-33 115.1 0.0 1.1e-19 70.9 0.0 2.4 2 0 0 2 2 2 2 Fasciclin domain Zn_clus PF00172.18 KXH52588.1 - 1.5e-07 31.4 11.3 3e-07 30.4 11.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KXH52588.1 - 0.0063 15.4 0.1 0.014 14.2 0.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF2306 PF10067.9 KXH52589.1 - 1.4e-18 67.5 9.6 2.8e-18 66.6 9.6 1.5 1 0 0 1 1 1 1 Predicted membrane protein (DUF2306) DUF373 PF04123.13 KXH52589.1 - 0.53 9.7 3.6 0.68 9.3 3.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF373) FA_desaturase PF00487.24 KXH52590.1 - 4.1e-24 85.8 14.0 8.7e-24 84.7 14.0 1.5 1 1 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 KXH52590.1 - 0.018 15.2 0.0 0.046 13.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3474) Abhydrolase_6 PF12697.7 KXH52591.1 - 9.2e-11 42.8 0.1 1.4e-10 42.2 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXH52591.1 - 8.4e-10 38.7 0.0 4.2e-09 36.4 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXH52591.1 - 3.5e-05 23.2 0.0 6.8e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 p450 PF00067.22 KXH52592.1 - 2.9e-45 154.9 0.0 3.6e-45 154.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Asp PF00026.23 KXH52593.1 - 1.9e-24 86.7 0.0 3.7e-24 85.7 0.0 1.4 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Beta_helix_2 PF18835.1 KXH52593.1 - 1.1 9.0 3.3 0.91 9.3 0.1 2.3 3 0 0 3 3 3 0 Beta helix repeat of Inulin fructotransferase Pro-kuma_activ PF09286.11 KXH52594.1 - 5.8e-28 98.0 0.0 1.3e-27 96.9 0.0 1.6 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KXH52594.1 - 1.2e-05 24.7 0.2 2.3e-05 23.8 0.2 1.4 1 0 0 1 1 1 1 Subtilase family Peptidase_S15 PF02129.18 KXH52595.1 - 2.2e-39 135.7 0.0 1e-36 127.0 0.0 2.2 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 KXH52595.1 - 1.8e-22 80.4 0.1 1.6e-21 77.3 0.0 2.4 2 1 0 2 2 2 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain ADH_zinc_N PF00107.26 KXH52596.1 - 1.1e-10 41.6 0.2 3.1e-10 40.2 0.1 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KXH52596.1 - 0.0057 16.5 0.0 0.01 15.7 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_N PF08240.12 KXH52596.1 - 0.016 15.1 0.0 0.074 12.9 0.0 2.0 1 1 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain MFS_1 PF07690.16 KXH52597.1 - 1.3e-17 63.7 31.9 4.5e-13 48.8 21.2 2.5 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH52597.1 - 0.66 8.8 28.9 0.022 13.6 3.6 3.8 3 1 1 4 4 4 0 Sugar (and other) transporter Catalase PF00199.19 KXH52598.1 - 4.7e-175 582.3 0.1 6.9e-175 581.7 0.1 1.2 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 KXH52598.1 - 1.7e-12 47.3 0.0 3.6e-12 46.3 0.0 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive CoA_transf_3 PF02515.17 KXH52600.1 - 6.9e-33 114.3 0.0 2.6e-31 109.1 0.0 2.1 2 0 0 2 2 2 2 CoA-transferase family III Na_H_Exchanger PF00999.21 KXH52601.1 - 1.1e-44 152.8 13.2 2.2e-44 151.8 13.1 1.4 1 1 0 1 1 1 1 Sodium/hydrogen exchanger family TrkH PF02386.16 KXH52602.1 - 1.3e-100 337.3 6.5 2.1e-98 330.0 0.5 2.1 2 0 0 2 2 2 2 Cation transport protein LepB_GAP_C PF18227.1 KXH52602.1 - 0.049 14.1 0.1 0.11 13.0 0.1 1.5 1 0 0 1 1 1 0 LepB GAP domain C-terminal subdomain Questin_oxidase PF14027.6 KXH52603.1 - 1.5e-75 254.8 0.0 1.8e-75 254.6 0.0 1.0 1 0 0 1 1 1 1 Questin oxidase-like MFS_1 PF07690.16 KXH52604.1 - 2.4e-40 138.5 37.9 2.4e-40 138.5 37.9 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH52604.1 - 4.7e-10 38.9 14.6 4.7e-10 38.9 14.6 2.8 1 1 1 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 KXH52604.1 - 0.00071 18.0 5.5 0.00071 18.0 5.5 3.9 2 2 0 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family BATS PF06968.13 KXH52605.1 - 3.1e-24 84.9 1.0 8.3e-24 83.6 0.1 2.2 2 1 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 KXH52605.1 - 7e-15 55.8 0.1 1.3e-14 54.9 0.1 1.5 1 0 0 1 1 1 1 Radical SAM superfamily PALP PF00291.25 KXH52606.1 - 1.3e-59 202.0 0.9 1.5e-59 201.8 0.9 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Git3 PF11710.8 KXH52607.1 - 3.6e-20 72.6 5.6 6e-20 71.9 5.6 1.3 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.21 KXH52607.1 - 4.1e-07 29.6 0.3 5.8e-07 29.1 0.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Dicty_CAR PF05462.11 KXH52607.1 - 1e-06 28.1 7.0 5.9e-06 25.6 4.6 2.1 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor GPR_Gpa2_C PF11970.8 KXH52607.1 - 0.057 13.5 0.0 0.17 12.0 0.0 1.8 1 0 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 C-term HET PF06985.11 KXH52608.1 - 3.3e-16 60.0 1.6 6.5e-16 59.0 1.6 1.5 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PP2C PF00481.21 KXH52609.1 - 7.9e-33 114.2 0.0 2.7e-32 112.4 0.0 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C RdRP PF05183.12 KXH52611.1 - 1.8e-131 439.7 0.0 2.4e-131 439.3 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase FAD_binding_3 PF01494.19 KXH52612.1 - 2.7e-15 56.5 5.9 1.3e-14 54.3 3.5 2.6 1 1 1 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 KXH52612.1 - 4.8e-07 29.9 0.1 1.3e-06 28.6 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXH52612.1 - 5.1e-05 22.7 1.5 0.00059 19.2 1.0 2.2 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXH52612.1 - 0.00017 20.8 2.7 0.00028 20.1 1.6 1.8 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 KXH52612.1 - 0.00017 21.3 1.7 0.00017 21.3 1.7 2.3 3 0 0 3 3 3 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KXH52612.1 - 0.0011 17.7 0.5 0.0019 17.0 0.5 1.5 1 1 0 1 1 1 1 HI0933-like protein Thi4 PF01946.17 KXH52612.1 - 0.0022 17.3 0.1 0.0039 16.5 0.1 1.3 1 0 0 1 1 1 1 Thi4 family AlaDh_PNT_C PF01262.21 KXH52612.1 - 0.0037 16.6 0.1 0.0062 15.9 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 KXH52612.1 - 0.0039 16.3 0.5 0.26 10.3 0.3 2.3 2 0 0 2 2 2 1 Lycopene cyclase protein GIDA PF01134.22 KXH52612.1 - 0.03 13.4 0.3 0.046 12.8 0.3 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 KXH52612.1 - 0.039 13.2 2.9 0.41 9.9 1.0 2.4 1 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 KXH52612.1 - 0.1 12.5 1.7 0.19 11.6 0.1 2.1 2 1 1 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.6 KXH52612.1 - 0.22 11.5 1.6 0.62 10.0 0.2 2.5 3 1 0 3 3 3 0 FAD-NAD(P)-binding p450 PF00067.22 KXH52613.1 - 6.5e-62 209.8 0.0 7.6e-62 209.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans_2 PF11951.8 KXH52614.1 - 1.1e-14 54.1 0.2 1.8e-14 53.4 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3829 PF12889.7 KXH52614.1 - 0.15 11.5 0.2 0.63 9.5 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3829) Fungal_trans PF04082.18 KXH52615.1 - 1.3e-12 47.4 0.0 2e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH52615.1 - 1.5e-08 34.6 10.4 2.3e-08 34.0 10.4 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HET PF06985.11 KXH52616.1 - 2.1e-21 76.8 0.3 1e-19 71.3 0.3 2.3 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Chromate_transp PF02417.15 KXH52618.1 - 0.0061 16.7 0.8 0.0097 16.1 0.8 1.3 1 0 0 1 1 1 1 Chromate transporter LRR_8 PF13855.6 KXH52619.1 - 1.6e-27 95.0 37.7 1.3e-05 24.8 5.5 8.4 4 2 4 10 10 10 8 Leucine rich repeat LRR_4 PF12799.7 KXH52619.1 - 7e-25 86.7 38.2 8.7e-06 26.0 1.1 9.2 6 3 4 11 11 11 8 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KXH52619.1 - 0.0021 18.3 25.2 0.76 10.6 0.5 10.2 13 0 0 13 13 13 1 Leucine Rich Repeat LRR_6 PF13516.6 KXH52619.1 - 0.017 15.1 16.1 14 6.0 0.2 8.3 9 0 0 9 9 9 0 Leucine Rich repeat LRR_9 PF14580.6 KXH52619.1 - 0.031 13.8 20.0 1.1 8.7 0.2 5.3 2 2 2 5 5 5 0 Leucine-rich repeat DUF2628 PF10947.8 KXH52622.1 - 0.5 10.8 3.4 0.66 10.4 1.9 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2628) COesterase PF00135.28 KXH52624.1 - 3.3e-87 293.5 0.5 3.8e-71 240.5 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 KXH52624.1 - 0.00027 20.9 0.0 0.0011 18.8 0.0 1.9 2 1 0 2 2 2 1 alpha/beta hydrolase fold Med25_VWA PF11265.8 KXH52625.1 - 0.13 12.0 0.1 0.22 11.3 0.1 1.3 1 0 0 1 1 1 0 Mediator complex subunit 25 von Willebrand factor type A DUF3526 PF12040.8 KXH52625.1 - 3.9 7.9 7.6 0.66 10.5 0.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3526) Sugar_tr PF00083.24 KXH52626.1 - 1.4e-74 251.6 24.4 1.7e-74 251.4 24.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH52626.1 - 7.3e-23 81.1 22.6 1.2e-22 80.3 22.6 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 KXH52626.1 - 3.4e-07 29.5 4.3 3.6e-07 29.4 0.4 2.1 2 0 0 2 2 2 1 MFS_1 like family Phage_holin_2_4 PF16082.5 KXH52626.1 - 0.12 12.2 0.6 0.75 9.6 0.1 2.3 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like Peptidase_S8 PF00082.22 KXH52627.1 - 3.5e-41 141.4 4.7 6.6e-41 140.5 4.7 1.4 1 0 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 KXH52627.1 - 3.5e-06 27.7 0.0 8.1e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 Fn3-like domain PG_isomerase_N PF18353.1 KXH52627.1 - 1.2 9.6 4.9 3 8.3 0.1 2.5 2 0 0 2 2 2 0 Phosphoglucose isomerase N-terminal domain MFS_1 PF07690.16 KXH52629.1 - 1.6e-39 135.8 47.7 4.5e-24 85.0 20.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH52629.1 - 0.0002 20.4 38.0 0.0014 17.5 19.1 3.0 1 1 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.7 KXH52629.1 - 0.0066 15.4 18.8 0.025 13.4 2.4 2.7 1 1 0 2 2 2 2 MFS_1 like family SVM_signal PF12113.8 KXH52629.1 - 0.39 10.7 0.1 0.39 10.7 0.1 2.2 2 0 0 2 2 2 0 SVM protein signal sequence Lipase_GDSL_2 PF13472.6 KXH52630.1 - 1.7e-05 25.3 0.1 0.00039 20.9 0.1 2.1 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KXH52630.1 - 9e-05 22.5 0.0 0.0001 22.3 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase ADH_zinc_N PF00107.26 KXH52632.1 - 1.3e-08 34.9 0.2 2.5e-08 34.0 0.2 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXH52632.1 - 4e-08 33.1 0.1 2.7e-07 30.4 0.1 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Pec_lyase_C PF00544.19 KXH52634.1 - 3e-18 66.2 7.5 1.6e-16 60.6 7.5 2.3 1 1 0 1 1 1 1 Pectate lyase CBM_1 PF00734.18 KXH52634.1 - 1.8e-12 47.0 8.7 1.8e-12 47.0 8.7 2.3 2 0 0 2 2 2 1 Fungal cellulose binding domain Beta_helix PF13229.6 KXH52634.1 - 3.4e-05 23.7 11.3 0.00012 21.9 10.0 2.2 1 1 1 2 2 2 2 Right handed beta helix region Acyl-CoA_dh_2 PF08028.11 KXH52634.1 - 1.9 8.7 5.7 0.12 12.6 0.4 1.8 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain DUF5427 PF10310.9 KXH52634.1 - 2.5 7.0 10.8 3.7 6.4 10.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5427) FAM220 PF15487.6 KXH52634.1 - 3.4 7.2 8.0 9.8 5.7 8.0 1.8 1 0 0 1 1 1 0 FAM220 family SOG2 PF10428.9 KXH52634.1 - 4.1 6.5 16.7 5.6 6.0 16.7 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Methyltransf_23 PF13489.6 KXH52635.1 - 3.1e-19 69.4 0.0 5.2e-19 68.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH52635.1 - 1.3e-12 48.3 0.0 3.1e-12 47.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH52635.1 - 2.9e-11 43.9 0.0 7.5e-11 42.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH52635.1 - 5.1e-10 40.0 0.0 2.9e-09 37.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH52635.1 - 1.3e-07 31.5 0.0 2.3e-06 27.5 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 KXH52635.1 - 9e-05 21.9 0.0 0.00022 20.6 0.0 1.6 1 1 0 1 1 1 1 O-methyltransferase domain Ubie_methyltran PF01209.18 KXH52635.1 - 0.00016 21.1 0.0 0.0015 17.9 0.0 2.2 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KXH52635.1 - 0.0083 15.7 0.0 0.048 13.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_4 PF02390.17 KXH52635.1 - 0.017 14.6 0.0 0.095 12.2 0.0 2.0 2 0 0 2 2 2 0 Putative methyltransferase FMO-like PF00743.19 KXH52638.1 - 1.2e-26 93.3 0.0 1.4e-19 69.9 0.0 2.3 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KXH52638.1 - 2.1e-13 50.2 0.0 3.1e-11 43.1 0.0 2.3 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXH52638.1 - 3.5e-12 46.1 0.0 6.1e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXH52638.1 - 1.4e-09 37.6 0.0 6.4e-08 32.1 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KXH52638.1 - 1.3e-06 28.5 0.1 0.00018 21.5 0.1 2.7 1 1 0 1 1 1 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KXH52638.1 - 1.4e-06 28.4 0.0 3.3e-05 24.0 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXH52638.1 - 5.1e-06 26.3 0.4 0.0011 18.6 0.0 2.7 3 0 0 3 3 3 2 FAD dependent oxidoreductase Amino_oxidase PF01593.24 KXH52638.1 - 0.0021 17.4 0.0 2 7.6 0.0 2.6 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.19 KXH52638.1 - 0.0083 15.4 0.5 0.092 12.0 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 KXH52638.1 - 0.076 12.2 0.0 0.38 10.0 0.0 1.9 2 0 0 2 2 2 0 Thi4 family 2-Hacid_dh_C PF02826.19 KXH52638.1 - 0.12 11.7 0.0 1.3 8.4 0.0 2.1 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF2235 PF09994.9 KXH52639.1 - 1.3e-42 146.2 0.0 1.6e-42 145.8 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Helo_like_N PF17111.5 KXH52640.1 - 1.3e-12 47.5 0.1 1.9e-12 47.0 0.1 1.2 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins RhgB_N PF09284.10 KXH52641.1 - 2.5e-83 279.5 0.2 7.9e-83 277.8 0.2 1.8 1 1 0 1 1 1 1 Rhamnogalacturonan lyase B, N-terminal CBM-like PF14683.6 KXH52641.1 - 7.6e-34 117.0 0.0 1.4e-33 116.1 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.6 KXH52641.1 - 4.2e-20 71.3 4.1 5.9e-20 70.8 1.8 2.5 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.6 KXH52641.1 - 0.0089 16.3 1.4 0.036 14.3 1.4 2.1 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain DPM3 PF08285.11 KXH52642.1 - 1.2e-35 121.6 0.2 1.3e-35 121.5 0.2 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Abhydrolase_3 PF07859.13 KXH52643.1 - 1.7e-62 211.0 0.0 2.2e-62 210.7 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KXH52643.1 - 1.7e-07 31.0 0.0 2.6e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.28 KXH52643.1 - 0.00011 21.2 0.0 0.00097 18.1 0.0 1.9 2 0 0 2 2 2 1 Carboxylesterase family Ribonuc_L-PSP PF01042.21 KXH52644.1 - 7.2e-37 126.1 0.0 7.9e-37 126.0 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Pirin PF02678.16 KXH52644.1 - 0.013 15.5 0.0 0.016 15.2 0.0 1.2 1 0 0 1 1 1 0 Pirin DUF2529 PF10740.9 KXH52644.1 - 0.018 14.7 0.0 0.023 14.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2529) MFS_1 PF07690.16 KXH52645.1 - 4.4e-33 114.7 30.1 4.8e-33 114.5 27.0 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily BT1 PF03092.16 KXH52645.1 - 0.019 13.2 4.5 0.01 14.1 0.9 2.0 2 0 0 2 2 2 0 BT1 family HET PF06985.11 KXH52646.1 - 1.1e-16 61.5 0.0 2.5e-16 60.4 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Trp_DMAT PF11991.8 KXH52647.1 - 5.2e-66 223.5 0.0 6.5e-66 223.2 0.0 1.0 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase Tyrosinase PF00264.20 KXH52650.1 - 4.4e-23 82.7 2.9 8.6e-23 81.8 2.9 1.4 1 0 0 1 1 1 1 Common central domain of tyrosinase P-mevalo_kinase PF04275.14 KXH52650.1 - 4.3e-19 68.6 0.0 7.7e-19 67.7 0.0 1.4 1 0 0 1 1 1 1 Phosphomevalonate kinase FAD_binding_4 PF01565.23 KXH52650.1 - 3.8e-18 65.6 2.7 2.3e-17 63.1 2.9 2.1 2 0 0 2 2 2 1 FAD binding domain Pribosyltran PF00156.27 KXH52650.1 - 5.3e-18 65.0 0.0 1.4e-17 63.6 0.0 1.7 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KXH52650.1 - 0.0066 15.9 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.6 KXH52650.1 - 0.087 12.3 0.1 0.24 10.9 0.0 1.7 2 0 0 2 2 2 0 Phosphoribosyl transferase DUF4407 PF14362.6 KXH52654.1 - 2.7 7.2 7.5 2.2 7.5 1.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) MCM_bind PF09739.9 KXH52654.1 - 3.9 5.8 5.0 0.31 9.4 0.2 1.5 2 0 0 2 2 2 0 Mini-chromosome maintenance replisome factor Oxidored-like PF09791.9 KXH52655.1 - 2.6e-24 84.6 3.2 2.6e-24 84.6 3.2 2.1 2 0 0 2 2 2 1 Oxidoreductase-like protein, N-terminal GCIP PF13324.6 KXH52655.1 - 0.12 12.0 0.7 0.17 11.4 0.7 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Wtap PF17098.5 KXH52655.1 - 0.12 12.3 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 WTAP/Mum2p family Pribosyltran PF00156.27 KXH52657.1 - 4e-07 29.7 0.1 1.1e-06 28.3 0.1 1.7 1 1 0 1 1 1 1 Phosphoribosyl transferase domain HU-CCDC81_bac_2 PF18175.1 KXH52657.1 - 0.14 12.1 0.1 0.37 10.7 0.0 1.7 2 0 0 2 2 2 0 CCDC81-like prokaryotic HU domain 2 Methyltransf_2 PF00891.18 KXH52658.1 - 7.8e-21 74.3 0.0 1.3e-20 73.6 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_16 PF10294.9 KXH52704.1 - 4.1e-05 23.4 0.0 6e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 KXH52704.1 - 0.0045 16.4 0.0 0.0069 15.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Fungal_trans PF04082.18 KXH52749.1 - 4.3e-21 75.1 1.5 6.9e-21 74.5 1.5 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain HpcH_HpaI PF03328.14 KXH52750.1 - 6.5e-31 107.2 0.0 8.1e-31 106.9 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PEP-utilizers_C PF02896.18 KXH52750.1 - 5.2e-05 22.5 0.4 0.00097 18.3 0.4 2.6 2 2 1 3 3 3 1 PEP-utilising enzyme, TIM barrel domain 2-Hacid_dh_C PF02826.19 KXH52751.1 - 6.6e-46 155.9 0.0 9.8e-46 155.3 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KXH52751.1 - 1.4e-21 76.5 0.0 1.7e-21 76.3 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AdoHcyase_NAD PF00670.21 KXH52751.1 - 0.0045 17.1 0.0 0.0098 16.0 0.0 1.5 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_2 PF03446.15 KXH52751.1 - 0.092 12.9 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Fungal_trans PF04082.18 KXH52752.1 - 1.9e-15 56.6 0.2 3.8e-15 55.7 0.2 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain SGL PF08450.12 KXH52753.1 - 1.6e-48 165.5 0.0 2e-48 165.1 0.0 1.0 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 KXH52753.1 - 1.3e-08 34.5 3.2 0.035 14.1 0.0 5.8 6 0 0 6 6 6 2 NHL repeat Str_synth PF03088.16 KXH52753.1 - 3.2e-08 33.6 0.0 0.0044 17.1 0.0 4.2 2 2 2 4 4 4 2 Strictosidine synthase Arylesterase PF01731.20 KXH52753.1 - 4.9e-05 23.4 0.0 0.011 16.0 0.0 3.0 3 0 0 3 3 3 1 Arylesterase PQQ_3 PF13570.6 KXH52753.1 - 0.00052 20.4 0.4 2.1 9.0 0.0 4.5 4 1 0 4 4 4 1 PQQ-like domain Lactonase PF10282.9 KXH52753.1 - 0.0038 16.5 0.0 0.0083 15.4 0.0 1.5 1 1 1 2 2 2 1 Lactonase, 7-bladed beta-propeller Sugar_tr PF00083.24 KXH52754.1 - 2.5e-86 290.3 15.0 2.9e-86 290.1 15.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH52754.1 - 1.1e-22 80.4 11.3 1.1e-22 80.4 11.3 2.2 1 1 0 2 2 2 1 Major Facilitator Superfamily p450 PF00067.22 KXH52755.1 - 2.8e-54 184.6 0.0 3.3e-54 184.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 GST_C_3 PF14497.6 KXH52756.1 - 2.3e-33 114.3 0.1 4e-33 113.5 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KXH52756.1 - 8.1e-06 26.0 0.0 1.4e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KXH52756.1 - 0.00011 22.2 0.0 0.00029 20.8 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KXH52756.1 - 0.16 12.4 0.0 1.1 9.6 0.0 2.3 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Peptidase_C41 PF05417.11 KXH52758.1 - 0.16 11.8 0.1 0.27 11.1 0.1 1.4 1 0 0 1 1 1 0 Hepatitis E cysteine protease Mannitol_dh_C PF08125.13 KXH52759.1 - 2.1e-74 250.1 0.0 3e-74 249.6 0.0 1.2 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.23 KXH52759.1 - 9.4e-50 168.7 0.0 1.7e-49 167.9 0.0 1.4 1 0 0 1 1 1 1 Mannitol dehydrogenase Rossmann domain FPRL1_inhibitor PF16104.5 KXH52760.1 - 0.081 13.1 0.2 2.3 8.4 0.1 2.1 1 1 1 2 2 2 0 Formyl peptide receptor-like 1 inhibitory protein Spectrin PF00435.21 KXH52761.1 - 0.04 14.4 6.2 2.2 8.8 0.9 2.8 2 0 0 2 2 2 0 Spectrin repeat DUF2937 PF11157.8 KXH52761.1 - 0.05 13.3 1.1 0.48 10.1 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) DUF1664 PF07889.12 KXH52761.1 - 0.095 12.7 8.4 0.5 10.4 3.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Prefoldin_2 PF01920.20 KXH52761.1 - 0.14 12.1 11.5 0.19 11.7 0.5 3.1 3 0 0 3 3 3 0 Prefoldin subunit Fib_alpha PF08702.10 KXH52761.1 - 0.17 12.0 9.8 0.095 12.9 3.4 2.5 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family DivIC PF04977.15 KXH52761.1 - 0.3 10.9 6.6 1.2 8.9 1.2 2.8 2 0 0 2 2 2 0 Septum formation initiator CLZ PF16526.5 KXH52761.1 - 0.34 11.3 6.1 0.78 10.1 0.5 3.4 3 1 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels GIT_CC PF16559.5 KXH52761.1 - 0.35 10.8 3.2 4.5 7.2 0.9 2.5 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor ZapB PF06005.12 KXH52761.1 - 0.45 11.0 12.7 0.22 12.0 1.6 3.2 3 0 0 3 3 3 0 Cell division protein ZapB DUF948 PF06103.11 KXH52761.1 - 0.7 10.2 6.2 4.3 7.7 0.1 2.6 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) FlaC_arch PF05377.11 KXH52761.1 - 1.4 9.4 4.7 2.1 8.8 0.5 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF760 PF05542.11 KXH52762.1 - 0.079 13.3 0.4 0.14 12.5 0.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF760) DUF4404 PF14357.6 KXH52762.1 - 0.098 13.3 0.5 0.098 13.3 0.5 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4404) DUF3332 PF11810.8 KXH52762.1 - 2.4 7.8 5.4 3.6 7.2 5.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3332) Fib_alpha PF08702.10 KXH52762.1 - 9.9 6.3 8.6 0.51 10.5 2.5 1.8 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family FDX-ACB PF03147.14 KXH52763.1 - 0.075 13.5 3.8 11 6.5 0.6 4.1 3 1 0 3 3 3 0 Ferredoxin-fold anticodon binding domain baeRF_family12 PF18856.1 KXH52763.1 - 0.39 11.3 11.8 9.2 6.8 0.3 4.5 3 2 1 4 4 4 0 Bacterial archaeo-eukaryotic release factor family 12 Annexin PF00191.20 KXH52763.1 - 1.6 8.9 12.8 6.7 6.9 0.0 5.4 5 1 2 7 7 7 0 Annexin DUF2939 PF11159.8 KXH52763.1 - 3.5 8.1 7.4 6.1 7.3 0.1 4.0 3 2 0 4 4 4 0 Protein of unknown function (DUF2939) Xpo1 PF08389.12 KXH52763.1 - 4.1 7.5 6.4 17 5.4 4.6 2.6 1 1 1 2 2 2 0 Exportin 1-like protein EMC1_C PF07774.13 KXH52764.1 - 0.14 11.8 0.4 0.35 10.5 0.3 1.4 1 1 0 1 1 1 0 ER membrane protein complex subunit 1, C-terminal Tannase PF07519.11 KXH52765.1 - 9.5e-123 410.5 0.4 1.1e-122 410.3 0.4 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_S9 PF00326.21 KXH52765.1 - 2.6e-05 23.8 0.7 0.001 18.6 0.2 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KXH52765.1 - 0.0025 17.1 0.0 0.021 14.1 0.0 2.2 3 0 0 3 3 3 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KXH52765.1 - 0.016 14.9 0.2 0.038 13.6 0.0 1.6 2 0 0 2 2 2 0 alpha/beta hydrolase fold Zn_clus PF00172.18 KXH52766.1 - 8e-07 29.1 10.1 1.6e-06 28.1 10.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NmrA PF05368.13 KXH52767.1 - 5.1e-64 216.0 0.7 6.8e-64 215.6 0.7 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXH52767.1 - 1.1e-20 74.3 1.3 1.9e-20 73.5 1.0 1.6 1 1 1 2 2 2 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KXH52767.1 - 4.2e-05 22.7 0.1 5.7e-05 22.3 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KXH52767.1 - 0.0092 15.5 0.3 0.016 14.6 0.3 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KXH52768.1 - 4.9e-34 117.9 0.0 6.1e-34 117.6 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXH52768.1 - 2e-12 47.4 0.1 2.8e-12 46.9 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KXH52768.1 - 6.1e-05 22.6 0.0 0.00035 20.1 0.0 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KXH52768.1 - 0.00081 19.3 0.2 0.0017 18.3 0.0 1.5 2 0 0 2 2 2 1 KR domain 3Beta_HSD PF01073.19 KXH52768.1 - 0.0025 16.9 0.0 0.0047 16.0 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 KXH52768.1 - 0.0068 15.9 0.2 0.22 11.0 0.1 2.1 2 0 0 2 2 2 1 short chain dehydrogenase GDP_Man_Dehyd PF16363.5 KXH52768.1 - 0.0082 15.6 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase DapB_N PF01113.20 KXH52768.1 - 0.028 14.5 0.0 0.055 13.6 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus FAD_binding_3 PF01494.19 KXH52769.1 - 3e-18 66.2 1.2 6.2e-08 32.3 0.0 3.1 3 0 0 3 3 3 3 FAD binding domain DAO PF01266.24 KXH52769.1 - 1.8e-11 44.2 1.8 1.2e-08 34.9 0.3 2.4 1 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXH52769.1 - 2.8e-07 30.1 2.4 4.2e-06 26.2 2.4 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXH52769.1 - 4.2e-07 30.1 0.2 1e-06 28.9 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KXH52769.1 - 1e-06 28.1 0.3 1.6e-06 27.5 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 KXH52769.1 - 0.00021 20.7 0.1 0.00038 19.8 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Trp_halogenase PF04820.14 KXH52769.1 - 0.00072 18.5 0.3 0.11 11.3 0.1 2.5 2 0 0 2 2 2 2 Tryptophan halogenase Lycopene_cycl PF05834.12 KXH52769.1 - 0.0051 15.9 0.1 0.25 10.4 0.0 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein HI0933_like PF03486.14 KXH52769.1 - 0.0055 15.5 0.3 0.011 14.4 0.0 1.6 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 KXH52769.1 - 0.0056 17.2 0.0 0.02 15.5 0.0 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 KXH52769.1 - 0.0058 15.7 0.0 0.032 13.3 0.0 1.9 2 0 0 2 2 2 1 Squalene epoxidase GIDA PF01134.22 KXH52769.1 - 0.03 13.4 0.2 0.054 12.6 0.1 1.5 2 0 0 2 2 2 0 Glucose inhibited division protein A FAM104 PF15434.6 KXH52769.1 - 0.048 14.2 0.2 0.14 12.8 0.0 1.7 2 0 0 2 2 2 0 Family 104 Pyr_redox_3 PF13738.6 KXH52769.1 - 0.059 12.6 0.6 0.11 11.8 0.1 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXH52769.1 - 0.15 12.1 0.3 2.9 7.8 0.0 2.9 3 0 0 3 3 3 0 FAD-NAD(P)-binding TrkA_N PF02254.18 KXH52769.1 - 0.16 12.2 0.6 0.78 10.0 0.0 2.3 2 0 0 2 2 2 0 TrkA-N domain adh_short PF00106.25 KXH52771.1 - 3.6e-43 147.3 0.0 4.5e-43 147.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXH52771.1 - 8.2e-35 120.4 0.0 1.8e-32 112.8 0.0 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH52771.1 - 1.6e-06 28.1 0.1 3.2e-06 27.2 0.1 1.6 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KXH52771.1 - 0.035 13.2 0.0 0.048 12.8 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KXH52771.1 - 0.072 12.2 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain Eno-Rase_NADH_b PF12242.8 KXH52771.1 - 0.17 11.7 0.3 0.76 9.6 0.1 2.2 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.21 KXH52771.1 - 0.17 11.3 0.0 0.36 10.3 0.0 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF4449 PF14613.6 KXH52772.1 - 1.4e-68 230.2 2.5 1.4e-68 230.2 2.5 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF4449) YlqD PF11068.8 KXH52772.1 - 0.029 14.8 1.2 0.029 14.8 1.2 2.4 2 0 0 2 2 2 0 YlqD protein Prp18 PF02840.15 KXH52772.1 - 0.13 12.3 7.1 0.16 12.0 0.0 2.9 2 1 1 3 3 3 0 Prp18 domain APH PF01636.23 KXH52773.1 - 2e-07 31.2 0.0 2.8e-06 27.4 0.0 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family Arcadin_1 PF18653.1 KXH52773.1 - 0.078 13.0 0.0 0.21 11.6 0.0 1.7 1 0 0 1 1 1 0 Arcadin 1 Clr5 PF14420.6 KXH52774.1 - 0.0052 17.0 0.1 0.017 15.3 0.1 2.0 2 0 0 2 2 2 1 Clr5 domain Herpes_US12 PF05363.12 KXH52774.1 - 0.026 15.3 0.4 0.22 12.2 1.5 2.0 2 0 0 2 2 2 0 Herpesvirus US12 family DDA1 PF10172.9 KXH52774.1 - 0.13 12.6 0.6 0.66 10.3 0.3 2.4 2 0 0 2 2 2 0 Det1 complexing ubiquitin ligase DUF5519 PF17648.1 KXH52776.1 - 0.073 12.9 0.2 0.13 12.1 0.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5519) Peptidase_M14 PF00246.24 KXH52777.1 - 1.3e-14 54.7 0.0 4e-14 53.1 0.0 1.6 1 1 1 2 2 2 1 Zinc carboxypeptidase AstE_AspA PF04952.14 KXH52777.1 - 0.036 13.1 0.2 0.087 11.9 0.0 1.6 2 0 0 2 2 2 0 Succinylglutamate desuccinylase / Aspartoacylase family MFS_1 PF07690.16 KXH52778.1 - 4.1e-17 62.2 41.1 5.1e-11 42.1 23.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily CBM_1 PF00734.18 KXH52778.1 - 0.069 13.1 0.1 0.14 12.2 0.1 1.5 1 0 0 1 1 1 0 Fungal cellulose binding domain IU_nuc_hydro PF01156.19 KXH52779.1 - 1.1e-14 54.8 0.0 1.6e-14 54.2 0.0 1.3 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase PTP_tm PF18861.1 KXH52780.1 - 0.0053 16.8 0.0 0.0088 16.1 0.0 1.4 1 0 0 1 1 1 1 Transmembrane domain of protein tyrosine phosphatase, receptor type J VSP PF03302.13 KXH52780.1 - 0.011 14.7 0.3 0.015 14.2 0.3 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein Mucin15 PF15672.5 KXH52780.1 - 0.031 13.8 3.8 0.08 12.4 2.7 1.9 1 1 1 2 2 2 0 Cell-membrane associated Mucin15 DUF824 PF05688.11 KXH52780.1 - 0.1 12.5 0.9 0.26 11.1 0.9 1.7 1 0 0 1 1 1 0 Salmonella repeat of unknown function (DUF824) DNA_ligase_A_M PF01068.21 KXH52781.1 - 5.2e-44 150.3 0.0 1.1e-43 149.2 0.0 1.6 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KXH52781.1 - 2e-41 142.2 0.0 4.3e-41 141.1 0.0 1.6 1 0 0 1 1 1 1 DNA ligase N terminus BRCT_2 PF16589.5 KXH52781.1 - 6.4e-17 61.7 0.0 1.1e-09 38.5 0.0 2.4 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain DNA_ligase_A_C PF04679.15 KXH52781.1 - 4e-16 59.4 0.1 1.5e-15 57.6 0.0 2.1 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 KXH52781.1 - 5.4e-16 59.3 0.0 1.2e-15 58.1 0.0 1.6 1 0 0 1 1 1 1 RNA ligase BRCT PF00533.26 KXH52781.1 - 3.2e-08 33.8 0.3 2.1e-06 28.0 0.0 3.2 3 1 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain DNA_ligase_IV PF11411.8 KXH52781.1 - 0.0011 19.1 0.0 0.0021 18.1 0.0 1.5 1 0 0 1 1 1 1 DNA ligase IV LIG3_BRCT PF16759.5 KXH52781.1 - 0.0038 17.5 0.0 0.46 10.8 0.0 2.5 2 0 0 2 2 2 1 DNA ligase 3 BRCT domain RTT107_BRCT_5 PF16770.5 KXH52781.1 - 0.0048 16.7 0.1 1 9.3 0.0 2.8 3 0 0 3 3 3 1 Regulator of Ty1 transposition protein 107 BRCT domain mRNA_cap_enzyme PF01331.19 KXH52781.1 - 0.019 14.8 0.0 0.37 10.6 0.0 2.6 2 1 0 2 2 2 0 mRNA capping enzyme, catalytic domain UPRTase PF14681.6 KXH52782.1 - 2.5e-66 223.1 0.0 2.2e-63 213.4 0.0 2.8 1 1 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 KXH52782.1 - 0.0043 16.6 0.3 0.0075 15.8 0.1 1.6 2 1 0 2 2 2 1 Phosphoribosyl transferase domain NAD_binding_10 PF13460.6 KXH52782.1 - 0.0098 15.8 0.0 0.016 15.1 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding TMP-TENI PF02581.17 KXH52782.1 - 0.065 12.6 0.4 0.4 10.0 0.1 2.0 2 0 0 2 2 2 0 Thiamine monophosphate synthase CRCB PF02537.15 KXH52783.1 - 1.2e-37 128.1 16.8 2.2e-22 79.2 9.8 2.5 2 0 0 2 2 2 2 CrcB-like protein, Camphor Resistance (CrcB) SGP PF17228.2 KXH52783.1 - 0.014 16.3 0.1 1.6 9.6 0.0 2.4 2 0 0 2 2 2 0 Sulphur globule protein Ribosomal_L13e PF01294.18 KXH52783.1 - 0.081 12.8 0.0 0.72 9.7 0.0 2.1 2 0 0 2 2 2 0 Ribosomal protein L13e Phage_cap_P2 PF05125.12 KXH52783.1 - 0.15 11.0 0.0 7.2 5.5 0.0 2.1 2 0 0 2 2 2 0 Phage major capsid protein, P2 family BDV_G PF06208.11 KXH52784.1 - 0.068 12.3 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Borna disease virus G protein DUF373 PF04123.13 KXH52784.1 - 0.1 12.0 1.6 0.76 9.2 0.1 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF373) DUF1404 PF07185.11 KXH52784.1 - 0.64 9.7 9.3 1.2 8.9 0.7 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF1404) zf-H2C2_2 PF13465.6 KXH52785.1 - 0.00018 21.7 3.1 0.00018 21.7 3.1 2.1 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2 PF00096.26 KXH52785.1 - 0.051 14.1 3.4 0.051 14.1 3.4 2.9 3 0 0 3 3 3 0 Zinc finger, C2H2 type FAD_binding_4 PF01565.23 KXH52786.1 - 7.5e-22 77.6 5.8 1.4e-21 76.7 5.8 1.5 1 0 0 1 1 1 1 FAD binding domain EthD PF07110.11 KXH52787.1 - 1.6e-13 51.6 0.1 1.9e-13 51.4 0.1 1.1 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 KXH52787.1 - 5.3e-05 23.6 0.0 7.8e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Methylmuconolactone methyl-isomerase Usher_TcfC PF17271.2 KXH52787.1 - 0.057 12.2 0.0 0.072 11.9 0.0 1.1 1 0 0 1 1 1 0 TcfC Usher-like barrel domain TRADD_N PF09034.10 KXH52787.1 - 0.18 11.8 0.0 0.25 11.4 0.0 1.2 1 0 0 1 1 1 0 TRADD, N-terminal domain peroxidase PF00141.23 KXH52788.1 - 3.9e-25 88.9 0.0 6.1e-25 88.3 0.0 1.3 1 0 0 1 1 1 1 Peroxidase Actino_peptide PF14408.6 KXH52788.1 - 0.063 13.4 1.3 0.82 9.8 0.3 2.8 3 0 0 3 3 3 0 Ribosomally synthesised peptide in actinomycetes S1 PF00575.23 KXH52789.1 - 5e-74 244.6 44.4 2.2e-14 53.6 1.6 13.2 13 0 0 13 13 13 11 S1 RNA binding domain TPR_19 PF14559.6 KXH52789.1 - 2.5e-05 24.7 1.3 0.85 10.2 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat RNase_II_C_S1 PF18614.1 KXH52789.1 - 3.8e-05 23.5 4.3 1.8 8.6 0.0 6.2 6 0 0 6 6 6 1 RNase II-type exonuclease C-terminal S1 domain S1_2 PF13509.6 KXH52789.1 - 4e-05 23.6 0.4 15 5.7 0.0 5.0 4 0 0 4 4 4 1 S1 domain TPR_14 PF13428.6 KXH52789.1 - 0.00014 22.4 1.8 5.4 8.1 0.0 5.0 3 1 2 5 5 5 2 Tetratricopeptide repeat NRDE-2 PF08424.10 KXH52789.1 - 0.025 13.7 4.0 0.032 13.4 0.8 2.3 1 1 1 2 2 2 0 NRDE-2, necessary for RNA interference TPR_16 PF13432.6 KXH52789.1 - 0.041 14.5 0.3 15 6.3 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat AEP1 PF17049.5 KXH52789.1 - 0.073 12.1 0.1 0.12 11.4 0.1 1.2 1 0 0 1 1 1 0 ATPase expression protein 1 DUF2187 PF09953.9 KXH52789.1 - 0.086 12.8 1.1 2.5 8.2 0.0 3.7 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2187) TPR_6 PF13174.6 KXH52789.1 - 0.13 12.9 0.4 22 6.0 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat PCB_OB PF17092.5 KXH52789.1 - 0.34 11.7 19.2 8.6 7.2 0.2 8.4 8 2 1 10 10 8 0 Penicillin-binding protein OB-like domain Peptidase_M16_C PF05193.21 KXH52791.1 - 6.9e-60 202.2 0.0 1.2e-59 201.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KXH52791.1 - 2.9e-39 134.4 0.0 2.1e-38 131.6 0.0 2.1 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Jun PF03957.13 KXH52791.1 - 0.093 12.6 4.1 0.2 11.5 4.1 1.5 1 0 0 1 1 1 0 Jun-like transcription factor Disulph_isomer PF06491.11 KXH52791.1 - 0.15 12.1 0.0 0.37 10.9 0.0 1.6 1 0 0 1 1 1 0 Disulphide isomerase FHA PF00498.26 KXH52792.1 - 4e-15 55.9 0.0 7.3e-15 55.1 0.0 1.5 1 0 0 1 1 1 1 FHA domain zf-RING_11 PF17123.5 KXH52792.1 - 7.3e-13 48.0 10.4 1.3e-12 47.2 10.4 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 KXH52792.1 - 2e-06 28.0 13.0 3.7e-06 27.2 13.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KXH52792.1 - 0.0097 16.2 8.7 0.027 14.7 8.7 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain Yop-YscD_cpl PF16697.5 KXH52792.1 - 0.013 15.8 0.0 0.029 14.7 0.0 1.5 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain zf-C3HC4 PF00097.25 KXH52792.1 - 0.013 15.3 12.8 0.023 14.6 12.8 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXH52792.1 - 0.15 12.0 10.3 0.26 11.3 10.3 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KXH52792.1 - 0.2 11.5 11.9 0.37 10.7 11.9 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KXH52792.1 - 0.21 11.7 3.3 0.41 10.7 3.3 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 KXH52792.1 - 0.41 10.7 11.8 0.86 9.7 11.8 1.6 1 0 0 1 1 1 0 RING-type zinc-finger lci PF12197.8 KXH52792.1 - 0.77 9.6 2.4 0.75 9.6 0.8 1.8 2 0 0 2 2 2 0 Bacillus cereus group antimicrobial protein Vps16_C PF04840.12 KXH52793.1 - 4.1e-86 289.0 0.0 5.8e-86 288.4 0.0 1.2 1 0 0 1 1 1 1 Vps16, C-terminal region Vps16_N PF04841.13 KXH52793.1 - 1.4e-83 281.0 0.0 2.5e-83 280.2 0.0 1.4 1 0 0 1 1 1 1 Vps16, N-terminal region ANAPC4_WD40 PF12894.7 KXH52793.1 - 0.071 13.4 0.0 12 6.3 0.0 3.0 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain ATG16 PF08614.11 KXH52794.1 - 2.8e-57 194.2 24.5 3.1e-57 194.0 24.5 1.0 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) CCDC144C PF14915.6 KXH52794.1 - 0.001 18.3 23.1 0.014 14.6 13.8 2.1 2 0 0 2 2 2 2 CCDC144C protein coiled-coil region TSC22 PF01166.18 KXH52794.1 - 0.0057 16.9 9.1 0.039 14.3 0.2 3.8 2 1 1 4 4 4 1 TSC-22/dip/bun family bZIP_1 PF00170.21 KXH52794.1 - 0.017 15.2 18.9 0.13 12.4 0.4 4.2 3 1 2 5 5 5 0 bZIP transcription factor Fez1 PF06818.15 KXH52794.1 - 0.086 13.3 17.6 0.8 10.1 3.1 2.2 1 1 1 2 2 2 0 Fez1 LAGLIDADG_WhiA PF14527.6 KXH52794.1 - 0.32 11.1 4.9 0.19 11.8 1.7 2.0 2 0 0 2 2 2 0 WhiA LAGLIDADG-like domain SurA_N PF09312.11 KXH52794.1 - 0.45 10.6 8.6 0.18 11.9 4.2 2.3 1 1 1 2 2 2 0 SurA N-terminal domain AAA_13 PF13166.6 KXH52794.1 - 0.91 8.1 12.9 1.2 7.7 12.9 1.2 1 0 0 1 1 1 0 AAA domain IFP_35_N PF07334.13 KXH52794.1 - 1.2 9.3 15.8 0.56 10.3 1.4 3.5 1 1 3 4 4 4 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus FAM76 PF16046.5 KXH52794.1 - 1.4 8.2 15.3 1.8 7.9 15.3 1.2 1 0 0 1 1 1 0 FAM76 protein Ndc1_Nup PF09531.10 KXH52794.1 - 2.5 6.7 9.5 2.9 6.5 9.5 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Med26 PF08711.11 KXH52794.1 - 4.9 7.2 6.8 2.1 8.4 0.1 3.3 3 1 0 3 3 3 0 TFIIS helical bundle-like domain YabA PF06156.13 KXH52794.1 - 6.4 7.5 19.7 21 5.8 0.4 3.3 2 1 0 2 2 2 0 Initiation control protein YabA ZapB PF06005.12 KXH52794.1 - 9.1 6.8 27.7 0.095 13.2 4.1 4.0 2 1 1 3 3 3 0 Cell division protein ZapB DOT1 PF08123.13 KXH52795.1 - 7.5e-72 241.2 0.0 1.1e-71 240.6 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_25 PF13649.6 KXH52795.1 - 0.045 14.5 0.0 0.097 13.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.6 KXH52795.1 - 0.16 12.0 0.0 0.38 10.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain DUF3482 PF11981.8 KXH52802.1 - 2 7.7 8.9 0.9 8.9 5.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3482) Ank_2 PF12796.7 KXH52803.1 - 5.1e-37 126.3 6.7 1.4e-09 38.4 0.0 8.3 4 3 1 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXH52803.1 - 1.1e-36 124.8 9.9 2.4e-05 24.8 0.0 10.2 6 3 4 10 10 10 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXH52803.1 - 6.1e-29 96.8 10.2 0.022 15.3 0.0 11.7 11 0 0 11 11 11 7 Ankyrin repeat Ank_5 PF13857.6 KXH52803.1 - 8.5e-16 57.8 7.4 0.0059 16.9 0.0 8.7 8 2 2 10 10 10 5 Ankyrin repeats (many copies) Ank PF00023.30 KXH52803.1 - 3.4e-14 52.5 22.4 0.18 12.3 0.2 10.7 11 0 0 11 11 11 6 Ankyrin repeat SDA1 PF05285.12 KXH52804.1 - 9.7e-90 301.5 61.6 3.8e-89 299.5 53.5 3.0 2 1 0 2 2 2 1 SDA1 NUC130_3NT PF08158.12 KXH52804.1 - 6.4e-20 71.2 0.2 1.8e-19 69.8 0.2 1.8 1 0 0 1 1 1 1 NUC130/3NT domain CSD2 PF17876.1 KXH52804.1 - 0.14 12.4 0.6 0.69 10.1 0.8 2.1 2 0 0 2 2 2 0 Cold shock domain YL1 PF05764.13 KXH52804.1 - 0.22 11.6 40.9 0.99 9.5 1.0 2.4 2 0 0 2 2 2 0 YL1 nuclear protein DUF5473 PF17567.2 KXH52805.1 - 0.043 14.1 0.4 0.043 14.1 0.4 2.4 3 0 0 3 3 3 0 Family of unknown function (DUF5473) zf-ACC PF17848.1 KXH52805.1 - 8.9 6.5 12.6 13 5.9 0.1 4.5 4 0 0 4 4 4 0 Acetyl-coA carboxylase zinc finger domain MFS_1 PF07690.16 KXH52806.1 - 1.3e-18 67.1 67.0 3.5e-13 49.2 53.3 4.3 1 1 1 2 2 2 2 Major Facilitator Superfamily PAM2 PF07145.15 KXH52807.1 - 0.0098 15.5 0.4 0.058 13.1 0.4 2.4 1 0 0 1 1 1 1 Ataxin-2 C-terminal region AMP-binding PF00501.28 KXH52808.1 - 7.3e-77 258.7 0.0 9.8e-77 258.3 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXH52808.1 - 3e-07 31.3 0.0 7.5e-07 30.0 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF5386 PF17360.2 KXH52808.1 - 0.059 13.3 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5386) MASE1 PF05231.14 KXH52809.1 - 0.0076 15.4 7.1 0.29 10.3 0.2 2.4 2 0 0 2 2 2 2 MASE1 DUF3483 PF11982.8 KXH52809.1 - 0.021 14.5 0.1 0.021 14.5 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3483) MFS_1 PF07690.16 KXH52810.1 - 9.2e-32 110.3 55.3 1.3e-26 93.4 29.4 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KXH52810.1 - 1.6e-05 23.6 1.7 1.6e-05 23.6 1.7 2.0 1 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) p450 PF00067.22 KXH52811.1 - 2e-72 244.5 0.0 2.4e-72 244.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Amidase PF01425.21 KXH52812.1 - 1.9e-98 330.4 0.0 3.3e-98 329.6 0.0 1.4 1 1 0 1 1 1 1 Amidase Fungal_trans_2 PF11951.8 KXH52813.1 - 9.5e-15 54.3 0.7 1.6e-13 50.2 0.7 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH52813.1 - 4.3e-07 30.0 8.6 7.9e-07 29.1 8.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 KXH52814.1 - 3.2e-18 65.8 19.1 7.7e-15 54.7 5.4 3.1 1 1 2 3 3 3 3 Major Facilitator Superfamily Bacteriocin_IIc PF10439.9 KXH52814.1 - 4.4 7.5 9.2 14 5.9 9.2 1.9 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Amidase PF01425.21 KXH52815.1 - 2.1e-90 303.8 0.0 3.8e-90 303.0 0.0 1.4 1 1 0 1 1 1 1 Amidase DUF1751 PF08551.10 KXH52816.1 - 9.3e-05 22.9 0.2 0.00016 22.2 0.2 1.4 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.22 KXH52816.1 - 0.01 15.8 4.3 0.022 14.8 4.3 1.5 1 1 0 1 1 1 0 Rhomboid family Prenyltransf PF01255.19 KXH52817.1 - 9.1e-83 277.2 0.0 1.3e-82 276.6 0.0 1.2 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase MSA-2c PF12238.8 KXH52817.1 - 0.067 13.2 0.3 0.096 12.7 0.3 1.2 1 0 0 1 1 1 0 Merozoite surface antigen 2c ING PF12998.7 KXH52818.1 - 8.6e-08 32.7 0.0 0.00079 20.0 0.0 2.5 2 0 0 2 2 2 2 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 KXH52818.1 - 1.1e-05 25.2 7.0 1.8e-05 24.5 7.0 1.4 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 KXH52818.1 - 0.12 12.7 1.6 0.27 11.5 1.6 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain PHD_2 PF13831.6 KXH52818.1 - 0.55 9.8 3.1 1 9.0 3.1 1.4 1 0 0 1 1 1 0 PHD-finger LRR_6 PF13516.6 KXH52819.1 - 0.00029 20.6 0.2 2.7 8.3 0.0 5.2 5 0 0 5 5 5 1 Leucine Rich repeat LRR_4 PF12799.7 KXH52819.1 - 0.009 16.4 2.8 0.23 11.9 0.0 4.5 5 1 1 6 6 6 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXH52819.1 - 0.024 14.4 2.7 1.4 8.8 0.0 3.8 5 0 0 5 5 5 0 Leucine rich repeat F-box-like PF12937.7 KXH52819.1 - 0.037 13.9 0.0 0.12 12.3 0.0 1.9 1 0 0 1 1 1 0 F-box-like Ribosomal_S19e PF01090.19 KXH52820.1 - 0.0061 16.3 0.0 0.012 15.3 0.0 1.5 1 1 0 1 1 1 1 Ribosomal protein S19e GRAB PF10375.9 KXH52821.1 - 2.4e-09 36.7 0.1 5.7e-09 35.5 0.1 1.7 1 0 0 1 1 1 1 GRIP-related Arf-binding domain Filament PF00038.21 KXH52821.1 - 2.9e-05 23.8 51.5 0.017 14.7 17.6 2.2 1 1 1 2 2 2 2 Intermediate filament protein Spc7 PF08317.11 KXH52821.1 - 9.6e-05 21.4 27.8 9.6e-05 21.4 27.8 2.8 1 1 2 3 3 3 2 Spc7 kinetochore protein T3SSipB PF16535.5 KXH52821.1 - 0.00034 21.1 11.7 0.00034 21.1 11.7 3.4 1 1 2 3 3 3 1 Type III cell invasion protein SipB Fib_alpha PF08702.10 KXH52821.1 - 0.0055 16.9 31.9 1.8 8.7 2.2 4.1 1 1 2 4 4 4 3 Fibrinogen alpha/beta chain family DUF5101 PF17031.5 KXH52821.1 - 0.0064 16.6 0.5 0.0064 16.6 0.5 4.7 4 3 1 5 5 4 1 Domain of unknown function (DUF5101) TPR_MLP1_2 PF07926.12 KXH52821.1 - 0.007 16.4 62.2 0.78 9.8 21.8 4.5 2 1 2 4 4 4 1 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.9 KXH52821.1 - 0.012 15.7 27.5 0.012 15.7 27.5 3.2 1 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ADIP PF11559.8 KXH52821.1 - 0.013 15.6 13.0 0.013 15.6 13.0 3.7 1 1 3 4 4 4 0 Afadin- and alpha -actinin-Binding JIP_LZII PF16471.5 KXH52821.1 - 0.015 15.5 2.5 0.015 15.5 2.5 6.2 4 2 2 6 6 6 0 JNK-interacting protein leucine zipper II Occludin_ELL PF07303.13 KXH52821.1 - 0.15 12.8 29.6 0.45 11.3 3.5 4.2 1 1 4 5 5 4 0 Occludin homology domain Golgin_A5 PF09787.9 KXH52821.1 - 0.17 11.3 58.1 0.084 12.3 29.1 3.2 1 1 2 3 3 3 0 Golgin subfamily A member 5 DUF1664 PF07889.12 KXH52821.1 - 0.18 11.8 30.8 0.55 10.3 2.4 4.2 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) GAS PF13851.6 KXH52821.1 - 0.32 10.3 53.6 0.45 9.8 8.7 4.0 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding DUF745 PF05335.13 KXH52821.1 - 0.57 9.9 43.7 0.34 10.6 11.8 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF745) DUF4201 PF13870.6 KXH52821.1 - 0.62 9.8 44.7 0.05 13.3 10.2 4.1 1 1 3 4 4 4 0 Domain of unknown function (DUF4201) ATG16 PF08614.11 KXH52821.1 - 0.65 10.2 73.3 13 6.0 18.3 4.5 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) MCC-bdg_PDZ PF10506.9 KXH52821.1 - 0.86 9.7 13.3 2.1 8.4 4.6 3.8 2 1 1 3 3 3 0 PDZ domain of MCC-2 bdg protein for Usher syndrome DUF641 PF04859.12 KXH52821.1 - 0.96 9.8 39.7 2.2 8.6 8.8 4.0 3 1 1 4 4 3 0 Plant protein of unknown function (DUF641) Seryl_tRNA_N PF02403.22 KXH52821.1 - 1.2 9.4 47.0 0.21 11.8 11.0 5.1 1 1 2 4 4 4 0 Seryl-tRNA synthetase N-terminal domain Atg14 PF10186.9 KXH52821.1 - 1.5 7.9 46.2 0.14 11.2 21.8 3.0 1 1 2 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 Fez1 PF06818.15 KXH52821.1 - 1.6 9.1 55.7 1.3 9.5 21.7 3.8 1 1 2 3 3 3 0 Fez1 Rootletin PF15035.6 KXH52821.1 - 1.6 8.7 52.4 0.91 9.5 23.8 3.2 2 1 1 3 3 3 0 Ciliary rootlet component, centrosome cohesion Prominin PF05478.11 KXH52821.1 - 2.1 6.2 25.5 6.6 4.5 9.8 2.4 1 1 1 2 2 2 0 Prominin ZYG-11_interact PF05884.12 KXH52821.1 - 2.8 7.3 13.1 3.4 7.0 1.9 2.9 2 1 0 2 2 2 0 Interactor of ZYG-11 NPV_P10 PF05531.12 KXH52821.1 - 3.1 8.3 17.6 0.36 11.3 0.6 4.6 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF4407 PF14362.6 KXH52821.1 - 3.4 6.9 45.2 11 5.3 23.6 3.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) TolA_bind_tri PF16331.5 KXH52821.1 - 3.4 7.8 35.4 0.14 12.2 2.3 4.7 2 2 2 4 4 4 0 TolA binding protein trimerisation APG17 PF04108.12 KXH52821.1 - 3.7 6.5 39.5 1.7 7.6 10.9 3.7 1 1 3 4 4 4 0 Autophagy protein Apg17 DUF3584 PF12128.8 KXH52821.1 - 4.3 4.7 52.0 9.4 3.6 50.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Laminin_II PF06009.12 KXH52821.1 - 4.6 7.3 38.9 1.8 8.6 4.1 4.1 2 2 2 4 4 4 0 Laminin Domain II KASH_CCD PF14662.6 KXH52821.1 - 4.6 7.0 56.8 0.074 12.9 19.1 3.3 1 1 3 4 4 3 0 Coiled-coil region of CCDC155 or KASH HAUS5 PF14817.6 KXH52821.1 - 5.1 5.7 40.5 27 3.3 26.1 2.6 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 5 Baculo_PEP_C PF04513.12 KXH52821.1 - 8 6.5 19.8 8 6.5 1.2 3.8 1 1 3 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus FPP PF05911.11 KXH52821.1 - 8.1 4.5 52.3 0.39 8.8 25.3 2.1 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil AIP3 PF03915.13 KXH52821.1 - 8.9 5.3 38.6 0.22 10.5 20.6 2.9 1 1 2 3 3 3 0 Actin interacting protein 3 RRM_1 PF00076.22 KXH52822.1 - 1.9e-12 46.8 0.0 4.6e-12 45.6 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KXH52822.1 - 0.00047 19.8 0.0 0.00086 18.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SMN PF06003.12 KXH52823.1 - 0.018 14.3 0.2 0.018 14.3 0.2 1.1 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Cu_bind_like PF02298.17 KXH52824.1 - 0.045 13.8 0.0 0.13 12.3 0.0 1.7 1 1 0 1 1 1 0 Plastocyanin-like domain DUF2057 PF09829.9 KXH52824.1 - 4.3 7.5 9.2 2.4 8.3 0.9 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2057) Alk_phosphatase PF00245.20 KXH52859.1 - 1.3e-102 343.9 0.0 1.6e-102 343.6 0.0 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 KXH52859.1 - 0.00019 20.9 0.0 0.00039 19.9 0.0 1.5 1 0 0 1 1 1 1 Metalloenzyme superfamily S_100 PF01023.19 KXH52859.1 - 0.061 13.0 0.1 0.14 11.8 0.1 1.6 1 0 0 1 1 1 0 S-100/ICaBP type calcium binding domain DNA_pol3_delta PF06144.13 KXH52859.1 - 0.062 13.1 0.1 0.16 11.8 0.1 1.6 1 0 0 1 1 1 0 DNA polymerase III, delta subunit FAR1 PF03101.15 KXH52860.1 - 5.5e-06 27.0 0.2 9.8e-06 26.2 0.2 1.3 1 0 0 1 1 1 1 FAR1 DNA-binding domain Tektin PF03148.14 KXH52860.1 - 0.00092 18.1 0.1 0.0012 17.7 0.1 1.1 1 0 0 1 1 1 1 Tektin family CLZ PF16526.5 KXH52860.1 - 0.0053 17.1 3.0 0.17 12.2 0.1 2.1 1 1 1 2 2 2 2 C-terminal leucine zipper domain of cyclic nucleotide-gated channels AFT PF08731.11 KXH52860.1 - 0.015 15.7 0.1 0.022 15.2 0.1 1.3 1 0 0 1 1 1 0 Transcription factor AFT Matrilin_ccoil PF10393.9 KXH52860.1 - 0.022 14.6 0.4 0.068 13.0 0.1 2.0 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin XhlA PF10779.9 KXH52860.1 - 0.025 14.8 0.0 0.11 12.7 0.0 1.9 1 1 1 2 2 2 0 Haemolysin XhlA Hemagglutinin PF00509.18 KXH52860.1 - 0.04 12.3 0.0 0.051 12.0 0.0 1.1 1 0 0 1 1 1 0 Haemagglutinin Tropomyosin_1 PF12718.7 KXH52860.1 - 0.081 13.1 0.0 0.19 11.8 0.0 1.5 1 1 0 1 1 1 0 Tropomyosin like Sugarporin_N PF11471.8 KXH52860.1 - 0.11 12.5 0.7 3.3 7.8 0.2 2.3 1 1 1 2 2 2 0 Maltoporin periplasmic N-terminal extension DASH_Dad1 PF08649.10 KXH52860.1 - 0.15 12.2 0.9 0.61 10.3 1.1 1.8 2 0 0 2 2 2 0 DASH complex subunit Dad1 HSBP1 PF06825.12 KXH52860.1 - 0.27 11.1 3.5 5.2 7.0 0.6 2.8 2 1 1 3 3 3 0 Heat shock factor binding protein 1 Mis14 PF08641.12 KXH52861.1 - 0.093 13.1 1.5 0.16 12.3 1.5 1.4 1 1 0 1 1 1 0 Kinetochore protein Mis14 like Ribosomal_L34e PF01199.18 KXH52862.1 - 4.6e-43 145.5 1.7 6.6e-43 144.9 1.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L34e Vps36-NZF-N PF16988.5 KXH52862.1 - 0.062 12.7 1.0 0.088 12.2 0.0 1.8 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain FhuF_C PF11575.8 KXH52862.1 - 0.46 10.5 5.4 1.7 8.7 0.3 2.8 3 0 0 3 3 3 0 FhuF 2Fe-2S C-terminal domain DUF498 PF04430.14 KXH52863.1 - 4.3e-30 104.0 0.0 5.8e-30 103.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) Abhydrolase_6 PF12697.7 KXH52864.1 - 2.2e-18 67.7 0.6 4.9e-18 66.5 0.6 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXH52864.1 - 1.7e-17 63.9 0.0 2.8e-17 63.2 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXH52864.1 - 7.2e-13 48.3 0.0 4.6e-12 45.7 0.0 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DSPc PF00782.20 KXH52864.1 - 7.4e-11 42.0 0.0 1.2e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Thioesterase PF00975.20 KXH52864.1 - 1.3e-07 32.0 0.0 2.7e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.13 KXH52864.1 - 0.00018 21.3 0.0 0.0015 18.3 0.0 2.1 2 0 0 2 2 2 1 PGAP1-like protein PTPlike_phytase PF14566.6 KXH52864.1 - 0.0012 19.0 0.0 0.0021 18.2 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 KXH52864.1 - 0.0015 18.2 0.0 0.0025 17.4 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase VirJ PF06057.11 KXH52864.1 - 0.0087 16.0 0.0 0.016 15.1 0.0 1.3 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) DUF3089 PF11288.8 KXH52864.1 - 0.015 14.9 0.0 0.028 14.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) LIDHydrolase PF10230.9 KXH52864.1 - 0.02 14.4 0.0 0.036 13.6 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Abhydrolase_3 PF07859.13 KXH52864.1 - 0.022 14.6 0.0 0.044 13.6 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF900 PF05990.12 KXH52864.1 - 0.035 13.6 0.0 0.057 12.9 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Lipase_3 PF01764.25 KXH52864.1 - 0.047 13.6 0.0 0.21 11.4 0.0 2.0 1 1 0 1 1 1 0 Lipase (class 3) Thiolase_C PF02803.18 KXH52864.1 - 0.072 12.7 0.1 20 4.9 0.0 2.9 3 0 0 3 3 3 0 Thiolase, C-terminal domain Esterase PF00756.20 KXH52864.1 - 0.12 12.0 0.0 1.4 8.5 0.0 2.2 2 0 0 2 2 2 0 Putative esterase Herpes_US12 PF05363.12 KXH52864.1 - 0.22 12.3 1.0 0.52 11.1 1.0 1.6 1 0 0 1 1 1 0 Herpesvirus US12 family Pil1 PF13805.6 KXH52870.1 - 4.8e-125 416.4 0.2 6.1e-125 416.0 0.2 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 FAM92 PF06730.11 KXH52870.1 - 0.12 11.8 2.8 0.13 11.7 0.8 1.9 1 1 1 2 2 2 0 FAM92 protein Octopine_DH PF02317.17 KXH52870.1 - 0.13 12.3 0.5 0.59 10.2 0.5 2.0 1 1 0 1 1 1 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain DUF1263 PF06882.12 KXH52870.1 - 0.14 12.3 0.0 0.54 10.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1263) CCDC84 PF14968.6 KXH52870.1 - 0.17 11.5 0.9 2 7.9 0.9 2.1 1 1 0 1 1 1 0 Coiled coil protein 84 LSM PF01423.22 KXH52871.1 - 0.00031 20.4 0.0 0.0022 17.6 0.0 1.9 1 1 0 1 1 1 1 LSM domain RcpC PF16976.5 KXH52871.1 - 0.0091 16.0 0.0 0.019 15.0 0.0 1.5 1 1 1 2 2 2 1 Flp pilus assembly protein RcpC/CpaB XPG_N PF00752.17 KXH52872.1 - 1.8e-33 115.0 0.0 4.3e-33 113.8 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 KXH52872.1 - 3.8e-27 94.5 0.0 1.3e-26 92.8 0.0 2.0 1 0 0 1 1 1 1 XPG I-region UIM PF02809.20 KXH52872.1 - 0.00036 20.2 10.6 0.0011 18.8 2.2 4.2 2 0 0 2 2 2 1 Ubiquitin interaction motif 5_3_exonuc PF01367.20 KXH52872.1 - 0.059 14.0 0.0 0.21 12.2 0.0 1.9 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold DUF1943 PF09172.11 KXH52872.1 - 0.42 9.8 4.7 0.069 12.4 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1943) DUF2229 PF09989.9 KXH52872.1 - 1.1 8.8 2.9 0.8 9.3 0.1 2.2 3 0 0 3 3 3 0 CoA enzyme activase uncharacterised domain (DUF2229) DUF2401 PF10287.9 KXH52873.1 - 5.3e-81 271.6 0.0 8.6e-81 270.9 0.0 1.3 1 0 0 1 1 1 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.9 KXH52873.1 - 1.7e-22 79.6 0.0 4.8e-22 78.2 0.0 1.8 1 0 0 1 1 1 1 Glycine-rich protein domain (DUF2403) Serglycin PF04360.12 KXH52873.1 - 0.17 11.9 1.5 0.33 10.9 1.5 1.4 1 0 0 1 1 1 0 Serglycin MSP1_C PF07462.11 KXH52873.1 - 0.56 8.8 0.9 0.77 8.4 0.9 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus NmrA PF05368.13 KXH52874.1 - 9.3e-66 221.7 0.1 1.1e-65 221.4 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXH52874.1 - 5.5e-21 75.3 0.1 8.3e-21 74.7 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KXH52874.1 - 1.3e-06 27.7 0.1 1.9e-06 27.1 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KXH52874.1 - 0.00087 18.8 0.1 0.0015 18.1 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 KXH52874.1 - 0.013 15.8 0.3 0.027 14.7 0.3 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Carb_kinase PF01256.17 KXH52922.1 - 5.9e-55 186.4 0.1 8.1e-55 185.9 0.1 1.1 1 0 0 1 1 1 1 Carbohydrate kinase HK PF02110.15 KXH52922.1 - 0.00036 20.0 0.0 0.00064 19.2 0.0 1.4 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family ATP-synt_ab PF00006.25 KXH52923.1 - 1.2e-73 247.3 0.0 1.7e-73 246.8 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 KXH52923.1 - 3.1e-47 160.0 0.2 5.5e-47 159.2 0.2 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 KXH52923.1 - 4.4e-15 55.9 3.0 1.1e-14 54.7 3.0 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain RbcS PF12338.8 KXH52923.1 - 0.095 12.9 0.5 1.6 8.9 0.4 2.7 2 0 0 2 2 2 0 Ribulose-1,5-bisphosphate carboxylase small subunit Ribosomal_L5_C PF00673.21 KXH52924.1 - 1.9e-22 79.2 0.0 2.8e-22 78.7 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 KXH52924.1 - 8.6e-20 70.8 0.0 3.2e-19 69.0 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L5 LSM PF01423.22 KXH52925.1 - 7.6e-18 64.0 0.0 1.2e-17 63.4 0.0 1.2 1 0 0 1 1 1 1 LSM domain MVL PF12151.8 KXH52926.1 - 0.2 11.5 0.0 19 5.2 0.0 2.3 2 0 0 2 2 2 0 Mannan-binding protein Ank_2 PF12796.7 KXH52930.1 - 8.1e-15 55.2 0.0 4.4e-08 33.6 0.0 3.6 4 1 0 4 4 4 2 Ankyrin repeats (3 copies) Ank PF00023.30 KXH52930.1 - 1.4e-14 53.8 0.7 0.0017 18.7 0.1 5.5 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.6 KXH52930.1 - 9.1e-13 48.4 0.3 0.0068 17.0 0.0 5.1 5 0 0 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXH52930.1 - 5.4e-12 44.8 0.9 0.0019 18.5 0.0 5.6 7 0 0 7 7 7 2 Ankyrin repeat Ank_5 PF13857.6 KXH52930.1 - 3.9e-09 36.6 0.2 0.0015 18.8 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeats (many copies) F-box-like PF12937.7 KXH52930.1 - 0.0012 18.7 0.1 0.0026 17.6 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXH52930.1 - 0.0024 17.7 0.0 0.0058 16.5 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 KXH52930.1 - 0.015 15.2 0.0 0.032 14.1 0.0 1.5 1 0 0 1 1 1 0 F-box Utp13 PF08625.11 KXH52930.1 - 0.079 12.9 0.0 0.94 9.4 0.0 2.4 2 0 0 2 2 2 0 Utp13 specific WD40 associated domain Ank_2 PF12796.7 KXH52932.1 - 5.8e-10 39.6 0.3 1.7e-05 25.3 0.0 3.3 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXH52932.1 - 1.6e-08 34.6 1.5 0.00063 20.0 0.1 4.3 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXH52932.1 - 4.1e-07 30.4 0.8 0.0028 18.2 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXH52932.1 - 7.1e-05 22.9 0.9 15 6.6 0.0 4.8 5 0 0 5 5 5 2 Ankyrin repeat Ank PF00023.30 KXH52932.1 - 7.2e-05 23.1 1.7 4.2 8.0 0.3 4.1 4 0 0 4 4 4 2 Ankyrin repeat Peptidase_M13_N PF05649.13 KXH52933.1 - 3e-66 224.7 0.0 4e-66 224.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 KXH52933.1 - 3.8e-58 196.5 0.5 6.5e-58 195.7 0.5 1.3 1 0 0 1 1 1 1 Peptidase family M13 DnaJ PF00226.31 KXH52934.1 - 4.5e-19 68.3 2.4 6.8e-19 67.8 2.4 1.3 1 0 0 1 1 1 1 DnaJ domain DUF456 PF04306.13 KXH52934.1 - 0.0094 16.2 0.7 0.017 15.4 0.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF456) TIP_N PF12457.8 KXH52934.1 - 0.014 15.8 3.0 0.024 15.0 2.3 1.7 2 0 0 2 2 2 0 Tuftelin interacting protein N terminal Bacteriocin_IIc PF10439.9 KXH52934.1 - 0.02 15.0 3.5 0.028 14.5 2.1 1.9 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide PT-VENN PF04829.13 KXH52934.1 - 1.6 8.8 4.8 1.7 8.8 1.7 2.5 3 0 0 3 3 3 0 Pre-toxin domain with VENN motif Mito_fiss_reg PF05308.11 KXH52937.1 - 2.6 8.1 7.7 4.5 7.3 7.7 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 KXH52937.1 - 5.3 6.4 11.8 13 5.1 11.8 1.7 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Ceramidase PF05875.12 KXH52939.1 - 1.3e-62 211.6 9.0 1.6e-62 211.3 9.0 1.0 1 0 0 1 1 1 1 Ceramidase COX2_TM PF02790.15 KXH52939.1 - 0.091 12.9 0.4 0.091 12.9 0.4 2.1 2 1 0 2 2 2 0 Cytochrome C oxidase subunit II, transmembrane domain TMEM208_SND2 PF05620.11 KXH52939.1 - 0.32 10.8 1.6 0.58 9.9 0.2 2.0 1 1 1 2 2 2 0 SRP-independent targeting protein 2/TMEM208 Vps62 PF06101.11 KXH52940.1 - 3.3e-10 38.9 0.9 4.8e-10 38.4 0.9 1.2 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 62 DUF1772 PF08592.11 KXH52941.1 - 1.1e-19 71.1 0.3 1.1e-19 71.1 0.3 1.9 1 1 1 2 2 2 1 Domain of unknown function (DUF1772) Peptidase_S41 PF03572.18 KXH52942.1 - 6.7e-07 29.0 0.0 1.5e-06 27.9 0.0 1.6 1 1 0 1 1 1 1 Peptidase family S41 Fasciclin PF02469.22 KXH52943.1 - 1.6e-35 122.1 1.0 2.2e-23 82.9 0.4 2.1 2 0 0 2 2 2 2 Fasciclin domain SnoaL PF07366.12 KXH52945.1 - 1.3e-16 60.5 0.0 2.4e-16 59.7 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 KXH52945.1 - 0.0012 19.5 0.0 0.0029 18.2 0.0 1.8 1 1 0 1 1 1 1 SnoaL-like domain Alpha-L-AF_C PF06964.12 KXH52946.1 - 2e-19 70.3 0.0 4.3e-19 69.3 0.0 1.5 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain HET PF06985.11 KXH52947.1 - 2.3e-28 99.4 0.0 4.3e-28 98.5 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) CbbQ_C PF08406.10 KXH52947.1 - 0.18 12.1 0.0 0.5 10.7 0.0 1.7 2 0 0 2 2 2 0 CbbQ/NirQ/NorQ C-terminal Raco_middle PF17651.1 KXH52948.1 - 0.042 13.5 0.3 0.072 12.8 0.3 1.3 1 0 0 1 1 1 0 RACo middle region Rho_Binding PF08912.11 KXH52948.1 - 0.81 10.5 4.5 0.23 12.3 1.5 1.6 2 0 0 2 2 2 0 Rho Binding adh_short_C2 PF13561.6 KXH52949.1 - 2.3e-59 200.8 1.8 2.7e-59 200.6 1.8 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXH52949.1 - 4.3e-43 147.1 1.7 5.5e-43 146.7 1.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXH52949.1 - 2.7e-15 56.7 0.5 3.8e-15 56.3 0.5 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXH52949.1 - 0.0048 16.4 0.2 0.018 14.5 0.2 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Amidase02_C PF12123.8 KXH52949.1 - 0.028 14.1 0.1 0.11 12.3 0.1 2.0 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase GDP_Man_Dehyd PF16363.5 KXH52949.1 - 0.031 13.7 0.1 0.16 11.3 0.0 1.9 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase LDcluster4 PF18306.1 KXH52949.1 - 0.041 13.5 0.1 0.073 12.7 0.1 1.4 1 0 0 1 1 1 0 SLOG cluster4 family DUF134 PF02001.16 KXH52949.1 - 0.086 13.4 0.3 0.19 12.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function DUF134 Thi4 PF01946.17 KXH52950.1 - 1.2e-09 37.8 1.4 1.8e-07 30.7 0.1 2.3 2 0 0 2 2 2 2 Thi4 family NAD_binding_8 PF13450.6 KXH52950.1 - 1.3e-09 38.2 0.5 4.2e-09 36.5 0.3 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXH52950.1 - 4.8e-07 29.7 1.8 1.9e-05 24.4 0.1 2.4 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KXH52950.1 - 1.2e-06 27.9 2.9 1.8e-06 27.3 1.1 2.0 2 0 0 2 2 2 1 FAD binding domain Amino_oxidase PF01593.24 KXH52950.1 - 1.6e-06 27.7 0.1 7e-06 25.6 0.1 2.2 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 KXH52950.1 - 8.1e-06 25.4 0.5 2.6e-05 23.8 0.5 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase GDI PF00996.18 KXH52950.1 - 8.2e-06 24.6 0.0 0.00016 20.3 0.0 2.1 2 0 0 2 2 2 1 GDP dissociation inhibitor FAD_binding_3 PF01494.19 KXH52950.1 - 0.00016 21.1 0.1 0.00025 20.4 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KXH52950.1 - 0.00067 18.5 0.8 0.0015 17.3 0.4 1.7 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.14 KXH52950.1 - 0.00073 18.9 0.1 0.0017 17.7 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase MCRA PF06100.11 KXH52950.1 - 0.0008 18.3 0.2 0.0013 17.7 0.2 1.3 1 0 0 1 1 1 1 MCRA family GIDA PF01134.22 KXH52950.1 - 0.0035 16.5 0.6 0.0071 15.5 0.6 1.5 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.27 KXH52950.1 - 0.011 16.2 1.1 0.077 13.6 0.4 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KXH52950.1 - 0.16 10.8 0.6 0.22 10.4 0.6 1.1 1 0 0 1 1 1 0 Tryptophan halogenase NTP_transf_3 PF12804.7 KXH52954.1 - 6.6e-20 72.1 0.6 1.6e-19 70.8 0.6 1.6 1 1 0 1 1 1 1 MobA-like NTP transferase domain F-box-like PF12937.7 KXH52955.1 - 0.0013 18.6 0.0 0.014 15.3 0.0 2.7 2 1 0 2 2 2 1 F-box-like Peptidase_S8 PF00082.22 KXH52956.1 - 4.9e-32 111.4 15.4 1.1e-31 110.2 15.4 1.5 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 KXH52956.1 - 0.0052 17.4 0.4 0.011 16.4 0.4 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 Cyc-maltodext_C PF10438.9 KXH52956.1 - 0.059 13.5 0.8 0.17 12.0 0.1 2.2 2 0 0 2 2 2 0 Cyclo-malto-dextrinase C-terminal domain SQS_PSY PF00494.19 KXH52957.1 - 4.8e-36 124.6 0.0 8.6e-36 123.8 0.0 1.4 2 0 0 2 2 2 1 Squalene/phytoene synthase RmlD_sub_bind PF04321.17 KXH52958.1 - 1.8e-14 53.5 0.0 7.3e-14 51.5 0.0 1.8 1 1 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 KXH52958.1 - 1.2e-11 44.5 0.0 2.4e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KXH52958.1 - 0.002 17.3 0.0 0.0033 16.6 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KXH52958.1 - 0.0087 15.5 0.0 0.15 11.4 0.0 2.3 2 1 1 3 3 3 1 GDP-mannose 4,6 dehydratase C2-set_2 PF08205.12 KXH52958.1 - 0.02 14.9 0.4 0.062 13.4 0.2 1.8 1 1 1 2 2 2 0 CD80-like C2-set immunoglobulin domain 3Beta_HSD PF01073.19 KXH52958.1 - 0.021 13.9 0.0 0.041 12.9 0.0 1.4 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DnaJ-X PF14308.6 KXH52959.1 - 3.9e-78 261.7 2.1 8.6e-78 260.6 2.1 1.6 1 0 0 1 1 1 1 X-domain of DnaJ-containing DnaJ PF00226.31 KXH52959.1 - 9.9e-27 92.9 1.1 2.1e-26 91.8 1.1 1.6 1 0 0 1 1 1 1 DnaJ domain LtuB PF17455.2 KXH52959.1 - 1.7 9.3 5.4 0.28 11.8 1.0 2.0 2 0 0 2 2 2 0 Late transcription unit B Isochorismatase PF00857.20 KXH52960.1 - 4.9e-25 88.7 0.0 6.2e-25 88.4 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family Amidohydro_1 PF01979.20 KXH52961.1 - 6.2e-05 22.5 0.1 0.00017 21.0 0.1 1.8 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KXH52961.1 - 0.0024 17.4 0.5 0.66 9.4 0.1 3.1 2 1 0 2 2 2 2 Amidohydrolase family HATPase_c_3 PF13589.6 KXH52964.1 - 0.0012 18.7 0.0 0.0022 17.8 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PilJ PF13675.6 KXH52964.1 - 0.066 13.2 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term ADIP PF11559.8 KXH52964.1 - 0.068 13.3 0.3 0.26 11.3 0.1 1.9 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding zf-C2H2_assoc3 PF16637.5 KXH52965.1 - 2.2 8.5 5.5 1.6 9.0 1.6 2.7 2 0 0 2 2 2 0 Putative zinc-finger between two C2H2 zinc-fingers on Patz Cyt-b5 PF00173.28 KXH52966.1 - 1.4e-14 54.0 0.0 2e-14 53.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NIBRIN_BRCT_II PF16508.5 KXH52967.1 - 2.2e-36 124.8 0.0 7.9e-36 123.0 0.0 2.0 2 0 0 2 2 2 1 Second BRCT domain on Nijmegen syndrome breakage protein FHA PF00498.26 KXH52967.1 - 7.3e-09 35.9 0.1 1.7e-08 34.7 0.1 1.7 1 0 0 1 1 1 1 FHA domain RTT107_BRCT_5 PF16770.5 KXH52967.1 - 0.0082 16.0 0.0 0.022 14.6 0.0 1.7 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain Yop-YscD_cpl PF16697.5 KXH52967.1 - 0.0087 16.3 0.0 0.1 13.0 0.0 2.4 1 1 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Mannosyl_trans PF05007.13 KXH52968.1 - 1.6e-76 257.6 13.4 2.1e-76 257.2 13.4 1.2 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.13 KXH52968.1 - 4.5e-10 39.1 9.9 3.1e-09 36.4 9.9 2.2 1 1 0 1 1 1 1 GPI transamidase subunit PIG-U GT87 PF09594.10 KXH52968.1 - 1.8e-05 24.6 21.2 1.8e-05 24.6 21.2 2.4 2 1 0 2 2 2 1 Glycosyltransferase family 87 Translin PF01997.16 KXH52969.1 - 4.7e-59 199.8 0.0 5.5e-59 199.6 0.0 1.0 1 0 0 1 1 1 1 Translin family NPV_P10 PF05531.12 KXH52969.1 - 0.14 12.6 0.0 0.83 10.2 0.0 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein PIN_8 PF18476.1 KXH52970.1 - 0.06 13.2 0.3 0.092 12.6 0.3 1.2 1 0 0 1 1 1 0 PIN like domain DUF3375 PF11855.8 KXH52970.1 - 0.07 12.0 0.1 0.11 11.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3375) FYVE_2 PF02318.16 KXH52970.1 - 0.38 11.0 5.1 1 9.6 5.1 1.7 1 0 0 1 1 1 0 FYVE-type zinc finger RTA1 PF04479.13 KXH52971.1 - 1.1e-64 217.9 10.4 1.1e-64 217.9 10.4 1.3 2 0 0 2 2 2 1 RTA1 like protein AAT PF03417.16 KXH52972.1 - 1.9e-26 93.2 0.0 2.2e-26 92.9 0.0 1.1 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase Sugar_tr PF00083.24 KXH52974.1 - 5.2e-82 276.1 23.4 5.9e-82 275.9 23.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH52974.1 - 2.4e-23 82.6 18.3 2.4e-23 82.6 18.3 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.6 KXH52974.1 - 3.3e-05 22.6 1.1 3.3e-05 22.6 1.1 2.7 2 1 0 2 2 2 1 MFS/sugar transport protein Ac76 PF05814.11 KXH52974.1 - 1.8 8.6 5.9 0.38 10.8 1.7 2.1 2 1 0 2 2 2 0 Orf76 (Ac76) NmrA PF05368.13 KXH52975.1 - 1.1e-21 77.5 0.0 1.5e-21 77.1 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXH52975.1 - 7.1e-11 42.3 0.9 1.1e-10 41.7 0.5 1.7 2 1 0 2 2 2 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KXH52975.1 - 0.0078 16.5 0.2 0.016 15.5 0.2 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain DapB_N PF01113.20 KXH52975.1 - 0.01 16.0 0.2 0.015 15.4 0.2 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.24 KXH52975.1 - 0.021 15.3 0.1 0.032 14.6 0.1 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.12 KXH52975.1 - 0.034 13.3 0.0 0.055 12.6 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein FAD_binding_4 PF01565.23 KXH52976.1 - 6e-26 90.8 0.7 6e-26 90.8 0.7 1.7 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 KXH52976.1 - 0.00047 20.2 0.1 0.0011 19.1 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like Cupin_3 PF05899.12 KXH52977.1 - 3.3e-05 23.5 0.0 5.2e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF861) EutQ PF06249.12 KXH52977.1 - 0.00036 20.3 0.0 0.00037 20.3 0.0 1.1 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Ectoine_synth PF06339.12 KXH52977.1 - 0.056 13.6 0.0 0.077 13.2 0.0 1.3 1 0 0 1 1 1 0 Ectoine synthase Pirin PF02678.16 KXH52977.1 - 0.16 12.0 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 Pirin Amidase PF01425.21 KXH52978.1 - 2.2e-66 224.7 0.0 3.1e-64 217.6 0.0 2.1 1 1 0 1 1 1 1 Amidase Peptidase_M14 PF00246.24 KXH52979.1 - 9.9e-38 130.6 0.2 1.5e-37 130.0 0.2 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase adh_short PF00106.25 KXH52981.1 - 2.4e-37 128.3 0.3 3.1e-37 127.9 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXH52981.1 - 8.3e-31 107.3 0.6 1.1e-30 107.0 0.6 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH52981.1 - 1.1e-11 44.9 0.1 1.4e-11 44.6 0.1 1.1 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.8 KXH52981.1 - 0.06 13.1 1.5 0.11 12.3 1.3 1.5 1 1 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase GPI-anchored PF10342.9 KXH52984.1 - 0.00053 20.7 0.3 0.00053 20.7 0.3 1.7 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Podoplanin PF05808.11 KXH52984.1 - 0.012 15.7 0.0 0.017 15.2 0.0 1.2 1 0 0 1 1 1 0 Podoplanin Yip1 PF04893.17 KXH52984.1 - 0.035 13.8 0.3 0.099 12.3 0.0 1.7 2 0 0 2 2 2 0 Yip1 domain Rax2 PF12768.7 KXH52984.1 - 0.079 12.4 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Alpha_GJ PF03229.13 KXH52984.1 - 0.081 13.5 5.7 0.14 12.7 5.7 1.3 1 0 0 1 1 1 0 Alphavirus glycoprotein J TMEM154 PF15102.6 KXH52984.1 - 0.11 12.4 0.4 0.29 11.0 0.3 1.7 1 1 1 2 2 2 0 TMEM154 protein family Ank_2 PF12796.7 KXH52985.1 - 0.042 14.4 0.0 1.7 9.3 0.0 2.6 1 1 1 2 2 2 0 Ankyrin repeats (3 copies) zf-C2H2 PF00096.26 KXH52985.1 - 1.4 9.5 4.7 0.78 10.3 0.4 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type DNA_primase_lrg PF04104.14 KXH52986.1 - 4.1e-81 272.3 0.0 6.2e-81 271.7 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit zf-FPG_IleRS PF06827.14 KXH52987.1 - 0.0016 18.2 0.3 0.092 12.6 0.1 2.2 2 0 0 2 2 2 1 Zinc finger found in FPG and IleRS Mut7-C PF01927.16 KXH52987.1 - 0.03 14.4 0.2 0.032 14.3 0.2 1.1 1 0 0 1 1 1 0 Mut7-C RNAse domain DUF1660 PF07874.11 KXH52987.1 - 0.049 14.1 1.8 2.7 8.5 0.0 2.3 1 1 1 2 2 2 0 Prophage protein (DUF1660) zinc_ribbon_9 PF14369.6 KXH52987.1 - 0.12 12.7 3.3 2.3 8.5 0.2 2.5 2 0 0 2 2 2 0 zinc-ribbon DNA_pol_viral_N PF00242.17 KXH52987.1 - 0.95 8.9 8.0 1 8.8 8.0 1.0 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Sporozoite_P67 PF05642.11 KXH52987.1 - 9.5 4.2 6.7 9.5 4.2 6.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Shisa PF13908.6 KXH53041.1 - 6.7e-05 23.2 0.0 8.7e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator ETRAMP PF09716.10 KXH53041.1 - 0.00025 21.0 1.7 0.00044 20.2 1.7 1.3 1 0 0 1 1 1 1 Malarial early transcribed membrane protein (ETRAMP) EphA2_TM PF14575.6 KXH53041.1 - 0.00046 21.0 1.5 0.0016 19.3 1.5 1.9 1 1 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Protocadherin PF08374.11 KXH53041.1 - 0.0015 18.5 0.1 0.002 18.1 0.1 1.2 1 0 0 1 1 1 1 Protocadherin FAM163 PF15069.6 KXH53041.1 - 0.0051 17.3 0.6 0.0067 16.9 0.6 1.2 1 0 0 1 1 1 1 FAM163 family DUF1218 PF06749.12 KXH53041.1 - 0.0094 16.5 0.3 0.012 16.1 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1218) SIT PF15330.6 KXH53041.1 - 0.012 16.0 0.0 0.052 14.0 0.0 1.8 1 1 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT RCR PF12273.8 KXH53041.1 - 0.014 16.0 7.8 0.13 12.9 7.8 2.1 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red Cauli_DNA-bind PF03310.13 KXH53041.1 - 0.028 14.5 0.3 0.055 13.5 0.3 1.4 2 0 0 2 2 1 0 Caulimovirus DNA-binding protein TMEM154 PF15102.6 KXH53041.1 - 0.062 13.2 0.0 0.11 12.4 0.0 1.5 1 1 0 1 1 1 0 TMEM154 protein family Cyclin_C PF02984.19 KXH53041.1 - 0.084 13.0 0.1 0.13 12.4 0.1 1.3 1 0 0 1 1 1 0 Cyclin, C-terminal domain DUF4446 PF14584.6 KXH53041.1 - 0.095 12.7 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) MAP17 PF15807.5 KXH53041.1 - 0.14 12.4 0.0 0.21 11.8 0.0 1.2 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Cadherin_C_2 PF16492.5 KXH53041.1 - 0.23 12.3 3.8 0.76 10.6 3.8 1.8 1 1 0 1 1 1 0 Cadherin cytoplasmic C-terminal ECSCR PF15820.5 KXH53041.1 - 0.37 10.6 4.9 0.63 9.9 4.9 1.5 1 1 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator Comm PF15957.5 KXH53041.1 - 0.46 10.8 3.7 0.8 10.1 3.6 1.4 1 1 0 1 1 1 0 Commissureless Fungus-induced PF10917.8 KXH53041.1 - 1.8 8.9 5.4 0.3 11.4 1.3 1.9 2 0 0 2 2 1 0 Fungus-induced protein TMEM52 PF14979.6 KXH53041.1 - 2.8 7.8 5.9 3.9 7.4 5.9 1.4 1 1 0 1 1 1 0 Transmembrane 52 Epimerase PF01370.21 KXH53042.1 - 2.2e-15 56.8 0.0 3e-15 56.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXH53042.1 - 8.7e-11 41.3 0.0 1.2e-10 40.8 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KXH53042.1 - 6.8e-07 29.4 0.2 1.1e-06 28.6 0.2 1.4 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KXH53042.1 - 1.2e-05 24.9 0.3 3.1e-05 23.6 0.3 1.8 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 KXH53042.1 - 1.3e-05 24.9 0.2 2.1e-05 24.2 0.2 1.4 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.12 KXH53042.1 - 2.2e-05 23.8 0.6 0.00011 21.5 0.0 2.2 2 1 0 2 2 2 1 Male sterility protein adh_short PF00106.25 KXH53042.1 - 0.0045 16.5 0.0 0.47 9.9 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase Glyco_transf_88 PF16849.5 KXH53042.1 - 0.024 13.6 0.0 14 4.5 0.0 3.0 1 1 2 3 3 3 0 Glycosyltransferase family 88 Polysacc_synt_2 PF02719.15 KXH53042.1 - 0.039 13.1 0.0 0.063 12.4 0.0 1.4 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein DUF5598 PF18127.1 KXH53042.1 - 0.088 13.2 0.0 0.26 11.8 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5598) XylR_N PF06505.11 KXH53043.1 - 0.11 12.3 0.0 8.5 6.2 0.0 2.1 1 1 1 2 2 2 0 Activator of aromatic catabolism Peptidase_S8 PF00082.22 KXH53044.1 - 3.3e-35 121.8 1.6 3.3e-35 121.8 0.4 1.6 2 0 0 2 2 2 1 Subtilase family Fungal_trans PF04082.18 KXH53047.1 - 7.1e-11 41.6 0.4 1.1e-10 41.0 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain UbiD PF01977.16 KXH53048.1 - 5.5e-122 407.5 0.0 6.5e-122 407.3 0.0 1.1 1 0 0 1 1 1 1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase Flavoprotein PF02441.19 KXH53049.1 - 5e-24 84.9 0.2 6.3e-24 84.5 0.2 1.1 1 0 0 1 1 1 1 Flavoprotein Fungal_trans PF04082.18 KXH53050.1 - 1.9e-09 37.0 0.0 3.2e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH53050.1 - 1.7e-08 34.5 9.5 3.2e-08 33.6 9.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gag_MA PF01140.19 KXH53050.1 - 0.048 13.4 0.0 0.098 12.4 0.0 1.4 1 0 0 1 1 1 0 Matrix protein (MA), p15 MFS_1 PF07690.16 KXH53051.1 - 3.2e-30 105.2 46.7 1.2e-20 73.8 17.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily BCS1_N PF08740.11 KXH53052.1 - 6.8e-37 127.3 0.0 1.3e-36 126.3 0.0 1.5 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 KXH53052.1 - 1.9e-22 80.1 0.0 5.5e-22 78.6 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KXH53052.1 - 8.3e-06 25.6 0.0 1.6e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 KXH53052.1 - 0.0084 16.7 0.0 0.02 15.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 KXH53052.1 - 0.032 13.4 0.0 0.05 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RNA_helicase PF00910.22 KXH53052.1 - 0.035 14.5 0.0 0.17 12.3 0.0 2.1 2 0 0 2 2 2 0 RNA helicase AAA_16 PF13191.6 KXH53052.1 - 0.077 13.4 0.0 0.24 11.8 0.0 1.7 1 1 0 2 2 2 0 AAA ATPase domain AAA_5 PF07728.14 KXH53052.1 - 0.085 12.9 0.0 0.36 10.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) YL1_C PF08265.11 KXH53052.1 - 0.14 11.9 0.1 0.31 10.8 0.1 1.5 1 0 0 1 1 1 0 YL1 nuclear protein C-terminal domain TIP49 PF06068.13 KXH53052.1 - 0.17 11.0 0.0 0.29 10.3 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain Peptidase_M14 PF00246.24 KXH53054.1 - 3e-63 214.3 0.0 3.9e-63 214.0 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.16 KXH53054.1 - 0.0012 19.2 0.1 0.0025 18.2 0.1 1.5 1 0 0 1 1 1 1 Carboxypeptidase activation peptide BNR_2 PF13088.6 KXH53055.1 - 1.5e-09 37.6 0.8 9.6e-05 21.8 0.1 2.7 2 1 1 3 3 3 2 BNR repeat-like domain Epimerase PF01370.21 KXH53056.1 - 3.9e-11 42.9 0.5 1.2e-10 41.3 0.5 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KXH53056.1 - 2.3e-07 30.2 1.4 0.00041 19.6 0.1 2.2 1 1 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 KXH53056.1 - 2.9e-06 27.3 1.5 1.1e-05 25.4 1.5 1.9 1 1 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KXH53056.1 - 0.00017 20.7 0.0 0.00031 19.9 0.0 1.5 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 KXH53056.1 - 0.00033 20.3 0.3 0.00061 19.4 0.2 1.5 1 1 0 1 1 1 1 NmrA-like family GDP_Man_Dehyd PF16363.5 KXH53056.1 - 0.078 12.4 0.2 0.18 11.2 0.2 1.6 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase tRNA_Me_trans PF03054.16 KXH53056.1 - 0.11 11.3 0.0 0.15 10.8 0.0 1.1 1 0 0 1 1 1 0 tRNA methyl transferase MFS_1 PF07690.16 KXH53057.1 - 3.7e-32 111.6 14.5 1.1e-27 96.9 13.1 2.6 2 1 1 3 3 3 2 Major Facilitator Superfamily Phage_holin_3_1 PF05106.12 KXH53057.1 - 0.052 14.0 0.4 0.26 11.7 0.4 2.2 1 0 0 1 1 1 0 Phage holin family (Lysis protein S) DUF2427 PF10348.9 KXH53057.1 - 0.86 9.4 7.6 0.14 11.9 1.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF2427) CBP4 PF07960.11 KXH53060.1 - 0.36 10.7 11.4 0.13 12.1 6.4 2.6 2 1 1 3 3 3 0 CBP4 MAJIN PF15077.6 KXH53060.1 - 0.63 9.8 3.7 1.2 8.9 3.5 1.5 1 1 0 1 1 1 0 Membrane-anchored junction protein DnaJ PF00226.31 KXH53062.1 - 3.5e-10 39.8 1.9 8e-10 38.7 0.2 2.3 3 0 0 3 3 3 1 DnaJ domain SirA PF10747.9 KXH53062.1 - 0.025 14.9 0.2 0.042 14.2 0.2 1.3 1 0 0 1 1 1 0 Sporulation inhibitor of replication protein SirA F-box-like_2 PF13013.6 KXH53063.1 - 0.00024 21.1 0.0 0.00031 20.7 0.0 1.2 1 0 0 1 1 1 1 F-box-like domain PRANC PF09372.10 KXH53063.1 - 0.00094 19.5 0.1 0.003 17.9 0.0 1.8 2 1 0 2 2 2 1 PRANC domain F-box PF00646.33 KXH53063.1 - 0.027 14.3 0.2 0.12 12.3 0.0 2.3 2 1 0 2 2 2 0 F-box domain F-box-like PF12937.7 KXH53063.1 - 0.39 10.6 2.5 0.68 9.9 0.2 2.5 2 1 0 2 2 2 0 F-box-like zf-RING_5 PF14634.6 KXH53065.1 - 0.0055 16.6 1.7 0.013 15.5 1.7 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 KXH53065.1 - 0.0062 16.8 10.3 0.01 16.2 7.9 2.6 2 1 0 2 2 2 1 Ring finger domain RINGv PF12906.7 KXH53065.1 - 0.58 10.3 5.4 1.5 9.0 5.4 1.8 1 0 0 1 1 1 0 RING-variant domain Prok-RING_4 PF14447.6 KXH53065.1 - 0.87 9.5 3.9 2.6 8.0 0.0 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 KXH53065.1 - 3.9 7.4 8.6 15 5.6 6.0 2.6 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 KXH53065.1 - 4.9 7.4 11.3 0.17 12.1 4.7 2.1 2 1 0 2 2 2 0 FANCL C-terminal domain DNA_pol_phi PF04931.13 KXH53067.1 - 1e-183 612.5 17.0 1.5e-183 612.0 17.0 1.3 1 0 0 1 1 1 1 DNA polymerase phi SDA1 PF05285.12 KXH53067.1 - 0.0015 18.1 25.7 0.0015 18.1 25.7 3.0 3 0 0 3 3 3 1 SDA1 Rhodanese PF00581.20 KXH53069.1 - 1.8e-13 50.9 0.0 3.5e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain Aldo_ket_red PF00248.21 KXH53081.1 - 9.9e-49 166.1 0.0 6.2e-47 160.2 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family HIT PF01230.23 KXH53082.1 - 3.5e-18 66.1 0.0 6.1e-18 65.4 0.0 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 KXH53082.1 - 1.4e-05 25.5 0.0 2.8e-05 24.6 0.0 1.4 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 KXH53082.1 - 2.4e-05 24.2 0.0 7.3e-05 22.6 0.0 1.7 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 DUF2267 PF10025.9 KXH53082.1 - 0.025 14.9 0.3 0.054 13.8 0.3 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2267) DNA_RNApol_7kD PF03604.13 KXH53083.1 - 3.6e-15 55.3 8.1 4.6e-15 55.0 8.1 1.1 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit GATA PF00320.27 KXH53083.1 - 0.0026 17.3 0.1 0.0026 17.3 0.1 2.2 2 1 0 2 2 2 1 GATA zinc finger Zn-ribbon_8 PF09723.10 KXH53083.1 - 0.0079 16.3 2.2 0.013 15.6 2.2 1.4 1 0 0 1 1 1 1 Zinc ribbon domain HypA PF01155.19 KXH53083.1 - 0.014 15.4 0.4 0.014 15.4 0.4 1.1 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA GFA PF04828.14 KXH53083.1 - 0.015 15.6 1.6 2.9 8.3 0.4 2.1 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Zn_ribbon_SprT PF17283.2 KXH53083.1 - 0.081 12.8 3.3 0.14 12.1 3.3 1.4 1 0 0 1 1 1 0 SprT-like zinc ribbon domain FYDLN_acid PF09538.10 KXH53083.1 - 0.21 12.3 0.7 0.28 11.9 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) zf_UBZ PF18439.1 KXH53083.1 - 0.62 9.7 3.2 9.3 5.9 0.1 2.2 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger TF_Zn_Ribbon PF08271.12 KXH53083.1 - 0.74 9.4 6.5 0.93 9.1 0.1 2.2 1 1 2 3 3 2 0 TFIIB zinc-binding ATP_bind_1 PF03029.17 KXH53084.1 - 2.7e-72 243.5 0.0 3.5e-72 243.1 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_24 PF13479.6 KXH53084.1 - 4.3e-05 23.3 0.0 7.9e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain GTP_EFTU PF00009.27 KXH53084.1 - 8.1e-05 22.2 0.0 0.012 15.2 0.0 2.7 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KXH53084.1 - 0.00029 20.9 0.0 0.0056 16.8 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase MeaB PF03308.16 KXH53084.1 - 0.00041 19.4 0.1 0.12 11.4 0.0 2.4 2 1 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 KXH53084.1 - 0.00057 20.3 0.0 0.0012 19.2 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 KXH53084.1 - 0.0014 18.4 0.0 0.0025 17.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain PRK PF00485.18 KXH53084.1 - 0.0016 18.2 0.0 0.0036 17.1 0.0 1.6 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family Zeta_toxin PF06414.12 KXH53084.1 - 0.0017 17.7 0.0 0.0042 16.4 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_22 PF13401.6 KXH53084.1 - 0.0019 18.5 0.0 0.0063 16.8 0.0 2.0 3 0 0 3 3 1 1 AAA domain NACHT PF05729.12 KXH53084.1 - 0.0025 17.7 0.0 0.0045 16.9 0.0 1.4 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.22 KXH53084.1 - 0.0029 16.8 0.0 0.008 15.4 0.0 1.6 2 0 0 2 2 2 1 NB-ARC domain cobW PF02492.19 KXH53084.1 - 0.003 17.2 0.2 0.039 13.6 0.2 2.3 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain G-alpha PF00503.20 KXH53084.1 - 0.0034 16.6 0.0 0.12 11.5 0.0 2.3 2 0 0 2 2 2 1 G-protein alpha subunit AAA_33 PF13671.6 KXH53084.1 - 0.0038 17.4 0.1 0.024 14.8 0.0 2.4 3 0 0 3 3 2 1 AAA domain SRP54 PF00448.22 KXH53084.1 - 0.006 16.2 0.0 0.028 14.0 0.0 2.1 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain FeoB_N PF02421.18 KXH53084.1 - 0.0062 16.1 0.1 0.12 11.9 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KXH53084.1 - 0.011 15.7 0.1 8.8 6.2 0.0 2.9 3 0 0 3 3 3 0 RsgA GTPase ATPase_2 PF01637.18 KXH53084.1 - 0.013 15.4 0.1 0.033 14.1 0.0 1.7 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Roc PF08477.13 KXH53084.1 - 0.014 15.6 0.0 2.8 8.2 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXH53084.1 - 0.016 14.7 0.0 3.2 7.2 0.0 2.4 2 0 0 2 2 2 0 ADP-ribosylation factor family Ras PF00071.22 KXH53084.1 - 0.016 14.8 0.0 1.9 8.1 0.0 2.7 3 0 0 3 3 3 0 Ras family AAA_18 PF13238.6 KXH53084.1 - 0.018 15.6 2.1 0.1 13.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain Pox_A32 PF04665.12 KXH53084.1 - 0.034 13.6 0.2 0.41 10.1 0.0 2.5 3 0 0 3 3 3 0 Poxvirus A32 protein KAP_NTPase PF07693.14 KXH53084.1 - 0.06 12.6 0.0 0.094 11.9 0.0 1.6 1 1 0 1 1 1 0 KAP family P-loop domain DUF87 PF01935.17 KXH53084.1 - 0.069 13.2 0.1 1.5 8.9 0.0 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain SRPRB PF09439.10 KXH53084.1 - 0.08 12.4 0.1 7.8 5.9 0.0 2.3 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit TsaE PF02367.17 KXH53084.1 - 0.089 12.8 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 KXH53084.1 - 0.13 12.3 0.0 0.34 10.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KXH53084.1 - 0.14 12.7 0.1 1.4 9.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 KXH53084.1 - 0.17 11.6 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase BNIP2 PF12496.8 KXH53084.1 - 8.5 6.8 8.5 21 5.6 8.1 1.7 1 1 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 CwfJ_C_2 PF04676.14 KXH53085.1 - 2.3e-27 95.7 0.1 2.3e-27 95.7 0.1 2.5 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 2 CwfJ_C_1 PF04677.15 KXH53085.1 - 1.9e-26 92.3 0.0 3.2e-26 91.6 0.0 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 FumaraseC_C PF10415.9 KXH53085.1 - 0.093 13.2 0.2 4.3 7.8 0.1 2.8 2 0 0 2 2 2 0 Fumarase C C-terminus Glyco_hydro_53 PF07745.13 KXH53086.1 - 3.3e-75 253.2 0.0 4e-75 252.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 Mpv17_PMP22 PF04117.12 KXH53087.1 - 2.1e-20 72.7 3.2 3.7e-20 71.9 0.2 2.5 3 0 0 3 3 3 1 Mpv17 / PMP22 family PGK PF00162.19 KXH53088.1 - 8e-152 505.6 1.7 9e-152 505.4 1.7 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase PA PF02225.22 KXH53088.1 - 0.00025 21.0 0.2 0.065 13.3 0.0 3.4 3 1 1 4 4 4 1 PA domain DUF3530 PF12048.8 KXH53088.1 - 0.21 10.9 0.0 0.31 10.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) DSS1_SEM1 PF05160.13 KXH53089.1 - 6.6e-24 83.7 12.6 7.8e-24 83.5 12.2 1.3 1 1 0 1 1 1 1 DSS1/SEM1 family TPR_11 PF13414.6 KXH53090.1 - 0.031 14.0 0.1 48 3.8 0.0 4.0 4 0 0 4 4 4 0 TPR repeat TPR_17 PF13431.6 KXH53090.1 - 0.066 13.6 0.3 19 5.9 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 KXH53090.1 - 0.071 13.8 6.7 5 7.8 0.5 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KXH53090.1 - 6.4 7.9 17.9 7.1 7.7 0.1 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat ChAPs PF09295.10 KXH53091.1 - 2.3e-153 510.9 0.0 2.9e-153 510.5 0.0 1.1 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_14 PF13428.6 KXH53091.1 - 5.8e-06 26.7 1.1 0.19 12.7 0.4 4.4 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 KXH53091.1 - 4.7e-05 23.4 0.6 0.015 15.4 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 KXH53091.1 - 5.5e-05 22.9 0.4 0.4 10.8 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 KXH53091.1 - 0.00015 21.6 1.5 0.055 13.6 0.6 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 KXH53091.1 - 0.00042 20.3 0.1 0.13 12.5 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 KXH53091.1 - 0.00073 20.0 0.0 1.5 9.4 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KXH53091.1 - 0.0066 16.2 0.3 3.9 7.5 0.1 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 KXH53091.1 - 0.02 15.1 1.1 9.1 6.7 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 KXH53091.1 - 0.025 15.2 0.1 32 5.4 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KXH53091.1 - 0.06 13.6 0.9 19 5.5 0.0 3.7 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 NO_synthase PF02898.15 KXH53093.1 - 4.3e-94 315.5 0.0 5.4e-91 305.3 0.0 2.2 2 0 0 2 2 2 2 Nitric oxide synthase, oxygenase domain Flavodoxin_1 PF00258.25 KXH53093.1 - 1.5e-10 41.4 0.0 9.8e-10 38.8 0.0 2.3 2 0 0 2 2 2 1 Flavodoxin FAD_binding_1 PF00667.20 KXH53093.1 - 5.2e-05 22.9 0.0 0.0017 17.9 0.0 2.2 1 1 1 2 2 2 1 FAD binding domain NAD_binding_1 PF00175.21 KXH53093.1 - 0.0017 18.9 0.0 0.0046 17.6 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain DUF1707 PF08044.11 KXH53093.1 - 0.02 14.9 1.0 0.1 12.6 0.4 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF1707) GATase PF00117.28 KXH53094.1 - 1.7e-36 125.8 0.0 5.3e-36 124.2 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase class-I GMP_synt_C PF00958.22 KXH53094.1 - 3.2e-35 120.1 0.0 6e-35 119.2 0.0 1.5 1 0 0 1 1 1 1 GMP synthase C terminal domain NAD_synthase PF02540.17 KXH53094.1 - 5.5e-08 32.2 0.0 1.5e-05 24.3 0.0 2.2 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.13 KXH53094.1 - 4.8e-06 26.5 0.0 9.7e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 QueC PF06508.13 KXH53094.1 - 0.0028 17.2 0.0 0.084 12.4 0.0 2.2 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 KXH53094.1 - 0.0038 16.1 0.1 0.0093 14.8 0.0 1.6 2 0 0 2 2 2 1 tRNA methyl transferase PAPS_reduct PF01507.19 KXH53094.1 - 0.033 14.2 0.0 0.052 13.6 0.0 1.3 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family ThiI PF02568.14 KXH53094.1 - 0.044 13.4 0.1 0.11 12.0 0.0 1.6 2 0 0 2 2 2 0 Thiamine biosynthesis protein (ThiI) ATP_bind_3 PF01171.20 KXH53094.1 - 0.087 12.6 0.0 0.27 11.0 0.0 1.9 2 0 0 2 2 2 0 PP-loop family Arginosuc_synth PF00764.19 KXH53094.1 - 0.11 11.8 0.1 0.28 10.4 0.1 1.6 2 0 0 2 2 2 0 Arginosuccinate synthase Mito_carr PF00153.27 KXH53095.1 - 3.9e-41 138.9 2.8 4.1e-20 71.5 0.1 3.7 2 1 1 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KXH53095.1 - 0.038 13.1 0.3 0.69 9.0 0.1 2.3 2 0 0 2 2 2 0 Gammaproteobacterial serine protease JAB PF01398.21 KXH53097.1 - 9.7e-09 35.2 1.3 5.2e-07 29.6 1.3 2.3 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease AdoHcyase PF05221.17 KXH53098.1 - 3e-131 437.0 0.0 1.3e-74 251.0 0.2 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 KXH53098.1 - 3.4e-83 277.6 2.3 5.4e-83 276.9 2.3 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 KXH53098.1 - 6e-07 29.0 0.2 3.7e-06 26.4 0.1 2.2 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.21 KXH53098.1 - 0.0043 16.8 0.1 0.0078 16.0 0.1 1.5 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase TrkA_N PF02254.18 KXH53098.1 - 0.006 16.8 0.0 0.013 15.8 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain IlvN PF07991.12 KXH53098.1 - 0.0079 15.8 0.2 0.015 14.8 0.2 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain 3HCDH_N PF02737.18 KXH53098.1 - 0.04 13.8 0.2 0.074 12.9 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Urocanase PF01175.18 KXH53098.1 - 0.12 12.0 0.4 0.2 11.3 0.4 1.3 1 0 0 1 1 1 0 Urocanase Rossmann-like domain 2-Hacid_dh_C PF02826.19 KXH53099.1 - 2.2e-56 190.0 0.0 3e-56 189.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KXH53099.1 - 2.8e-14 52.9 0.0 3.7e-14 52.5 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KXH53099.1 - 6.4e-07 29.7 0.0 1.1e-06 28.9 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 KXH53099.1 - 0.0048 16.5 0.0 0.0079 15.8 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain F420_oxidored PF03807.17 KXH53099.1 - 0.018 15.6 0.0 0.04 14.5 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Glutaminase PF04960.15 KXH53100.1 - 3e-112 374.5 0.1 3.7e-112 374.2 0.1 1.1 1 0 0 1 1 1 1 Glutaminase Zn_clus PF00172.18 KXH53101.1 - 0.012 15.7 5.4 0.02 15.0 5.4 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain HET PF06985.11 KXH53103.1 - 2.1e-20 73.6 0.0 5e-20 72.4 0.0 1.7 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF1688 PF07958.11 KXH53104.1 - 2.8e-174 579.8 0.0 3.1e-174 579.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) Q_salvage PF10343.9 KXH53104.1 - 3.4e-05 23.6 0.0 0.02 14.5 0.0 2.2 2 0 0 2 2 2 2 Potential Queuosine, Q, salvage protein family Gate PF07670.14 KXH53106.1 - 0.14 12.4 2.6 14 6.0 0.0 3.4 4 0 0 4 4 4 0 Nucleoside recognition Ank_2 PF12796.7 KXH53107.1 - 7.4e-64 212.3 1.6 3e-11 43.8 0.0 7.2 2 2 3 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXH53107.1 - 2.1e-50 168.5 7.2 3.3e-07 30.7 0.0 9.9 3 3 6 10 10 10 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXH53107.1 - 9.4e-46 148.5 12.1 0.00081 19.7 0.0 14.2 14 0 0 14 14 14 11 Ankyrin repeat Ank_5 PF13857.6 KXH53107.1 - 6.1e-44 147.5 10.2 4.9e-08 33.1 0.0 10.4 5 2 6 11 11 11 10 Ankyrin repeats (many copies) Ank PF00023.30 KXH53107.1 - 7.2e-38 127.4 21.5 0.00065 20.0 0.4 13.9 13 1 0 13 13 13 11 Ankyrin repeat Cid2 PF09774.9 KXH53108.1 - 8e-56 188.9 0.0 9.5e-56 188.6 0.0 1.1 1 0 0 1 1 1 1 Caffeine-induced death protein 2 NARP1 PF12569.8 KXH53109.1 - 1.1e-189 631.7 24.7 6.4e-188 625.8 19.2 2.2 2 0 0 2 2 2 2 NMDA receptor-regulated protein 1 TPR_19 PF14559.6 KXH53109.1 - 1.2e-19 70.6 24.6 0.00012 22.5 4.0 7.5 7 1 1 8 8 8 4 Tetratricopeptide repeat TPR_16 PF13432.6 KXH53109.1 - 5e-14 52.7 39.5 0.019 15.6 0.2 10.6 10 2 2 12 12 10 7 Tetratricopeptide repeat ANAPC3 PF12895.7 KXH53109.1 - 5.8e-13 48.9 17.6 6.7e-06 26.2 2.2 5.5 4 2 0 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 KXH53109.1 - 7.4e-10 38.2 40.4 0.0002 21.2 0.3 10.8 12 0 0 12 12 11 3 Tetratricopeptide repeat TPR_1 PF00515.28 KXH53109.1 - 4.5e-09 35.8 17.2 2.3e-05 24.0 0.5 7.9 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_12 PF13424.6 KXH53109.1 - 2.9e-08 33.9 25.4 1.3 9.4 0.1 8.7 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_14 PF13428.6 KXH53109.1 - 6.1e-08 32.8 30.3 0.0085 16.8 0.0 10.8 8 3 4 12 12 10 3 Tetratricopeptide repeat TPR_9 PF13371.6 KXH53109.1 - 9e-08 32.2 11.1 0.0018 18.4 0.1 6.4 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_11 PF13414.6 KXH53109.1 - 1.1e-07 31.4 12.4 7.6e-05 22.3 0.1 6.3 7 0 0 7 7 7 2 TPR repeat TPR_17 PF13431.6 KXH53109.1 - 1e-05 25.6 13.8 0.8 10.2 0.0 7.7 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_MalT PF17874.1 KXH53109.1 - 7.1e-05 22.3 11.3 0.067 12.5 0.1 3.3 2 1 1 3 3 3 3 MalT-like TPR region TPR_8 PF13181.6 KXH53109.1 - 0.00091 19.3 0.2 0.00091 19.3 0.2 6.8 8 0 0 8 8 7 1 Tetratricopeptide repeat NRDE-2 PF08424.10 KXH53109.1 - 0.0024 17.1 0.1 0.0024 17.1 0.1 1.9 2 0 0 2 2 1 1 NRDE-2, necessary for RNA interference TPR_3 PF07720.12 KXH53109.1 - 0.023 14.7 1.7 0.94 9.5 0.2 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Sel1 PF08238.12 KXH53109.1 - 0.043 14.5 1.8 7.2 7.4 0.0 3.1 2 0 0 2 2 2 0 Sel1 repeat TPR_4 PF07721.14 KXH53109.1 - 0.1 13.2 9.7 8.2 7.4 0.2 6.2 7 0 0 7 7 4 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KXH53109.1 - 0.11 12.6 11.1 13 6.0 0.2 5.2 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat TPR_7 PF13176.6 KXH53109.1 - 0.12 12.5 10.1 11 6.3 0.1 6.3 7 0 0 7 7 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 KXH53109.1 - 7.9 7.4 29.7 6.1 7.7 0.1 8.4 11 0 0 11 11 7 0 Tetratricopeptide repeat Glycos_transf_3 PF00591.21 KXH53110.1 - 3e-41 141.7 0.0 4e-41 141.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain AA_permease PF00324.21 KXH53117.1 - 2.1e-97 326.7 35.6 2.6e-97 326.4 35.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KXH53117.1 - 1.3e-19 70.3 39.6 1.6e-19 70.0 39.6 1.1 1 0 0 1 1 1 1 Amino acid permease FAA_hydrolase PF01557.18 KXH53118.1 - 0.00086 19.0 0.0 0.001 18.8 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family RHS PF03527.14 KXH53118.1 - 0.2 11.5 2.4 5.5 6.8 0.3 2.5 2 0 0 2 2 2 0 RHS protein Fungal_trans PF04082.18 KXH53119.1 - 1.7e-13 50.2 0.4 5.5e-13 48.6 0.4 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF3460 PF11943.8 KXH53122.1 - 0.07 13.4 2.4 0.22 11.8 1.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3460) Cu-binding_MopE PF11617.8 KXH53122.1 - 0.24 11.6 1.9 0.57 10.4 1.9 1.7 1 0 0 1 1 1 0 Putative metal-binding motif zf-MYND PF01753.18 KXH53123.1 - 4e-05 23.6 15.9 0.00015 21.8 15.9 2.1 1 0 0 1 1 1 1 MYND finger Ribosomal_L10 PF00466.20 KXH53124.1 - 0.0001 22.4 0.0 0.00039 20.5 0.0 2.0 1 1 0 1 1 1 1 Ribosomal protein L10 DUF5401 PF17380.2 KXH53124.1 - 0.025 12.7 2.4 0.035 12.2 2.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) AAA PF00004.29 KXH53126.1 - 8.5e-40 136.2 0.0 1.9e-39 135.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KXH53126.1 - 1.2e-18 66.8 0.1 2.4e-18 65.8 0.1 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 KXH53126.1 - 5.7e-07 29.2 0.0 1.2e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KXH53126.1 - 0.00011 22.6 1.7 0.02 15.3 0.0 3.0 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 KXH53126.1 - 0.00018 21.5 1.6 0.00071 19.6 0.1 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KXH53126.1 - 0.00035 20.3 0.0 0.00091 19.0 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 KXH53126.1 - 0.0018 18.4 0.4 0.011 15.9 0.0 2.4 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KXH53126.1 - 0.005 17.1 3.9 0.082 13.2 0.0 3.2 3 1 1 4 4 4 1 AAA domain PhoH PF02562.16 KXH53126.1 - 0.0051 16.3 0.2 0.08 12.4 0.1 2.4 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.21 KXH53126.1 - 0.0084 15.5 0.0 0.02 14.3 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 KXH53126.1 - 0.012 14.8 0.0 0.027 13.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_33 PF13671.6 KXH53126.1 - 0.014 15.6 0.0 0.034 14.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KXH53126.1 - 0.072 12.8 0.1 0.18 11.5 0.1 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_7 PF12775.7 KXH53126.1 - 0.11 12.0 0.0 0.31 10.5 0.0 1.8 1 1 0 1 1 1 0 P-loop containing dynein motor region Uds1 PF15456.6 KXH53126.1 - 0.23 11.6 3.1 0.6 10.3 3.1 1.8 1 0 0 1 1 1 0 Up-regulated During Septation RPN2_C PF18004.1 KXH53126.1 - 0.55 10.1 8.0 1.3 9.0 8.0 1.5 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain AAA_11 PF13086.6 KXH53126.1 - 0.6 9.9 0.0 0.6 9.9 0.0 2.6 3 0 0 3 3 3 0 AAA domain Hydrophobin_2 PF06766.11 KXH53127.1 - 7.1e-28 96.3 8.4 8.8e-28 96.0 8.4 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Ish1 PF10281.9 KXH53128.1 - 1.4e-87 287.6 23.5 1.9e-12 47.3 0.0 8.8 8 1 0 8 8 8 8 Putative stress-responsive nuclear envelope protein SAP PF02037.27 KXH53128.1 - 1.7e-09 37.2 0.0 0.83 9.5 0.0 7.1 7 1 0 7 7 7 3 SAP domain Slx4 PF09494.10 KXH53128.1 - 4.7e-05 23.3 1.3 44 4.1 0.0 6.3 7 1 0 7 7 7 0 Slx4 endonuclease HeH PF12949.7 KXH53128.1 - 0.00011 21.8 0.0 1.5 8.6 0.0 5.0 5 0 0 5 5 5 1 HeH/LEM domain SAM_2 PF07647.17 KXH53128.1 - 0.058 13.5 1.6 3.9 7.6 0.1 3.7 4 0 0 4 4 4 0 SAM domain (Sterile alpha motif) tRNA_lig_CPD PF08302.11 KXH53129.1 - 5.4e-95 317.6 0.0 7.9e-95 317.1 0.0 1.2 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain RNA_lig_T4_1 PF09511.10 KXH53129.1 - 1.5e-85 286.5 0.1 3.6e-85 285.3 0.0 1.7 2 0 0 2 2 2 1 RNA ligase tRNA_lig_kinase PF08303.11 KXH53129.1 - 8e-52 175.7 0.0 1.9e-51 174.5 0.0 1.7 1 0 0 1 1 1 1 tRNA ligase kinase domain AAA_18 PF13238.6 KXH53129.1 - 0.011 16.3 0.0 0.1 13.2 0.0 2.7 2 1 0 2 2 2 0 AAA domain MICSWaP PF17018.5 KXH53129.1 - 0.18 11.3 0.0 0.68 9.5 0.0 1.9 2 0 0 2 2 2 0 Spore wall protein Ank_5 PF13857.6 KXH53130.1 - 3.4e-08 33.6 0.1 1.1e-06 28.7 0.1 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXH53130.1 - 1e-05 25.5 0.9 0.001 19.3 0.2 3.1 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 KXH53130.1 - 1.2e-05 25.7 0.0 0.00055 20.5 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXH53130.1 - 1.3e-05 25.7 0.3 3.3e-05 24.4 0.3 1.7 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 KXH53130.1 - 0.0043 17.4 0.1 0.22 12.0 0.1 2.7 2 0 0 2 2 2 1 Ankyrin repeat Ribonuc_P_40 PF08584.11 KXH53131.1 - 7.3e-57 192.8 0.0 9.9e-57 192.4 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit UPF0020 PF01170.18 KXH53132.1 - 9.3e-09 35.2 0.0 5.9e-07 29.4 0.0 2.2 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Vac_ImportDeg PF09783.9 KXH53133.1 - 9.8e-70 233.6 0.6 1.2e-69 233.2 0.6 1.1 1 0 0 1 1 1 1 Vacuolar import and degradation protein Mago_nashi PF02792.14 KXH53134.1 - 1.5e-72 242.3 0.1 1.7e-72 242.2 0.1 1.0 1 0 0 1 1 1 1 Mago nashi protein Adaptin_N PF01602.20 KXH53135.1 - 2.4e-96 323.4 12.3 2.4e-96 323.4 12.3 1.6 2 0 0 2 2 2 1 Adaptin N terminal region Coatamer_beta_C PF07718.12 KXH53135.1 - 3.7e-60 201.9 0.6 8.5e-60 200.7 0.6 1.7 1 0 0 1 1 1 1 Coatomer beta C-terminal region Coatomer_b_Cpla PF14806.6 KXH53135.1 - 3.7e-57 191.8 0.0 1.3e-56 190.1 0.0 2.0 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Cnd1 PF12717.7 KXH53135.1 - 4.2e-13 49.7 7.4 8.5e-11 42.2 0.1 3.0 1 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KXH53135.1 - 3.2e-07 30.6 7.3 0.00064 20.1 0.0 4.9 2 1 4 6 6 6 3 HEAT repeats Coatomer_g_Cpla PF16381.5 KXH53135.1 - 0.00046 20.3 0.0 0.0016 18.6 0.0 2.0 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT PF02985.22 KXH53135.1 - 0.005 17.0 2.3 4.1 7.9 0.0 4.9 6 0 0 6 6 6 1 HEAT repeat AP4E_app_platf PF14807.6 KXH53135.1 - 0.011 16.1 0.2 0.037 14.4 0.2 2.0 1 0 0 1 1 1 0 Adaptin AP4 complex epsilon appendage platform DUF5578 PF17741.1 KXH53135.1 - 0.021 14.3 3.8 1.8 7.9 0.1 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5578) DUF1380 PF07128.12 KXH53135.1 - 0.052 13.7 0.5 1.1 9.4 0.3 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1380) Ku_PK_bind PF08785.11 KXH53135.1 - 0.22 11.7 2.8 0.55 10.4 0.6 2.8 2 1 0 2 2 2 0 Ku C terminal domain like UBD PF16455.5 KXH53136.1 - 2.7e-38 130.4 0.0 4.5e-38 129.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-binding domain ubiquitin PF00240.23 KXH53136.1 - 2.1e-08 33.8 0.0 4.3e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 KXH53136.1 - 0.0018 18.8 0.5 0.0047 17.5 0.2 1.8 1 1 1 2 2 2 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 KXH53136.1 - 0.016 15.3 0.1 0.029 14.5 0.1 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD PF11976.8 KXH53136.1 - 0.02 14.7 0.0 0.042 13.7 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Pre-SET PF05033.16 KXH53137.1 - 5.1e-19 68.9 4.6 5.1e-19 68.9 4.6 2.1 2 0 0 2 2 2 1 Pre-SET motif SET PF00856.28 KXH53137.1 - 2e-16 60.8 0.0 2e-15 57.6 0.0 2.4 2 2 0 2 2 2 1 SET domain Glyco_hydro_7 PF00840.20 KXH53138.1 - 1e-142 475.9 3.5 1.3e-142 475.6 3.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 HET PF06985.11 KXH53139.1 - 1.5e-13 51.3 1.5 3e-13 50.3 0.7 2.0 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Atypical_Card PF18461.1 KXH53139.1 - 0.062 13.5 0.0 8.9 6.6 0.1 2.6 2 0 0 2 2 2 0 Atypical caspase recruitment domain HET PF06985.11 KXH53141.1 - 4.5e-13 49.8 2.1 8e-13 49.0 2.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Haem_degrading PF03928.14 KXH53142.1 - 3.4e-33 114.2 1.3 6.1e-33 113.4 0.0 1.9 2 0 0 2 2 2 1 Haem-degrading HTH_Tnp_Tc3_2 PF01498.18 KXH53142.1 - 0.074 13.3 0.1 0.27 11.5 0.0 1.9 2 0 0 2 2 2 0 Transposase SnoaL_4 PF13577.6 KXH53143.1 - 9.9e-18 64.5 2.5 1.2e-17 64.2 2.5 1.1 1 0 0 1 1 1 1 SnoaL-like domain Ring_hydroxyl_B PF00866.18 KXH53143.1 - 0.061 13.4 0.0 0.088 12.9 0.0 1.2 1 0 0 1 1 1 0 Ring hydroxylating beta subunit CFEM PF05730.11 KXH53144.1 - 0.0014 18.7 3.0 0.0024 17.9 3.0 1.4 1 0 0 1 1 1 1 CFEM domain NCE101 PF11654.8 KXH53144.1 - 0.13 12.0 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 Non-classical export protein 1 Pacs-1 PF10254.9 KXH53144.1 - 0.21 10.5 0.1 0.39 9.6 0.1 1.3 1 0 0 1 1 1 0 PACS-1 cytosolic sorting protein G_path_suppress PF15991.5 KXH53144.1 - 9.5 6.3 20.7 0.65 10.1 14.6 1.8 2 0 0 2 2 2 0 G-protein pathway suppressor Ank_2 PF12796.7 KXH53145.1 - 3.4e-45 152.5 0.9 2.7e-12 47.1 0.0 5.5 3 2 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXH53145.1 - 9e-40 130.1 2.0 0.00018 21.6 0.0 10.9 11 0 0 11 11 11 9 Ankyrin repeat Ank_4 PF13637.6 KXH53145.1 - 2.6e-37 126.7 0.8 3.4e-09 37.1 0.0 8.5 5 2 4 9 9 9 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXH53145.1 - 1.1e-30 105.3 2.5 1.5e-05 25.2 0.0 7.7 5 2 2 7 7 7 6 Ankyrin repeats (many copies) Ank PF00023.30 KXH53145.1 - 8.3e-23 79.8 8.8 0.011 16.2 0.0 9.9 9 1 1 10 10 10 7 Ankyrin repeat p450 PF00067.22 KXH53146.1 - 3.1e-55 187.8 0.0 4e-55 187.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Asn_synthase PF00733.21 KXH53147.1 - 1.3e-65 222.4 0.0 2e-65 221.8 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.6 KXH53147.1 - 1.4e-34 118.6 0.0 5.3e-34 116.8 0.0 1.9 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_6 PF13522.6 KXH53147.1 - 1e-32 113.2 0.0 3e-32 111.6 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.8 KXH53147.1 - 4.5e-06 26.3 0.0 1.3e-05 24.8 0.0 1.7 2 0 0 2 2 2 1 Aluminium induced protein tRNA_Me_trans PF03054.16 KXH53147.1 - 0.021 13.6 0.0 0.035 12.9 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase NAD_synthase PF02540.17 KXH53147.1 - 0.045 12.9 0.0 0.084 12.0 0.0 1.4 1 0 0 1 1 1 0 NAD synthase DUF4938 PF16292.5 KXH53147.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4938) IER PF05760.12 KXH53148.1 - 0.12 12.7 2.9 0.19 12.0 2.9 1.3 1 0 0 1 1 1 0 Immediate early response protein (IER) BCAS3 PF12490.8 KXH53148.1 - 0.84 9.1 3.9 1.2 8.6 3.9 1.2 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 3 Sec62 PF03839.16 KXH53148.1 - 3 7.3 6.8 4.5 6.7 6.8 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 HSP90 PF00183.18 KXH53148.1 - 4.4 6.1 9.1 6.1 5.6 9.1 1.1 1 0 0 1 1 1 0 Hsp90 protein MFS_1 PF07690.16 KXH53149.1 - 4e-14 52.3 45.8 2.8e-12 46.2 44.1 2.4 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF2304 PF10066.9 KXH53149.1 - 9 6.6 9.0 1.4 9.1 3.2 2.8 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2304) Abhydrolase_1 PF00561.20 KXH53150.1 - 1.4e-21 77.3 0.0 1.2e-18 67.7 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 KXH53150.1 - 8e-21 74.1 0.1 2.6e-20 72.4 0.0 2.0 2 0 0 2 2 2 1 TAP-like protein Asp PF00026.23 KXH53151.1 - 2.9e-06 27.0 0.0 3.3e-05 23.5 0.0 2.0 1 1 0 1 1 1 1 Eukaryotic aspartyl protease DUF4328 PF14219.6 KXH53151.1 - 0.068 12.7 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) TraI_2B PF18340.1 KXH53153.1 - 0.048 13.7 0.2 0.072 13.2 0.2 1.3 1 0 0 1 1 1 0 DNA relaxase TraI 2B/2B-like domain AA_permease_2 PF13520.6 KXH53154.1 - 3.2e-72 243.7 31.8 3.8e-72 243.4 31.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXH53154.1 - 1.7e-22 79.7 29.3 2.1e-22 79.4 29.3 1.1 1 0 0 1 1 1 1 Amino acid permease DUF1229 PF06797.11 KXH53154.1 - 0.021 15.0 0.5 8.9 6.5 0.1 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1229) TauD PF02668.16 KXH53155.1 - 2.2e-16 60.4 0.0 2.1e-11 44.1 0.0 2.2 2 0 0 2 2 2 2 Taurine catabolism dioxygenase TauD, TfdA family RhoGAP PF00620.27 KXH53155.1 - 0.19 11.6 0.0 0.32 10.8 0.0 1.3 1 0 0 1 1 1 0 RhoGAP domain MFS_1 PF07690.16 KXH53156.1 - 6.1e-34 117.5 18.5 7.2e-33 114.0 19.0 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily 2-Hacid_dh_C PF02826.19 KXH53157.1 - 2e-44 151.0 0.1 2.8e-44 150.6 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KXH53157.1 - 1.8e-11 43.9 0.1 2.7e-11 43.2 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KXH53157.1 - 3.4e-05 24.1 0.0 6.2e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase GFO_IDH_MocA PF01408.22 KXH53157.1 - 0.0053 17.6 0.0 0.012 16.5 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold 3HCDH_N PF02737.18 KXH53157.1 - 0.039 13.8 0.0 0.076 12.9 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain p450 PF00067.22 KXH53158.1 - 2e-62 211.5 0.0 2.6e-62 211.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Proteasome PF00227.26 KXH53158.1 - 0.065 12.7 0.0 1 8.8 0.0 2.3 2 0 0 2 2 2 0 Proteasome subunit Abhydrolase_3 PF07859.13 KXH53159.1 - 1.7e-21 77.1 0.1 9.5e-18 64.8 0.1 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KXH53159.1 - 8.3e-08 32.0 0.0 0.0001 21.9 0.0 2.4 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 KXH53159.1 - 3e-07 31.3 5.6 4e-07 30.9 5.6 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase PF07224.11 KXH53159.1 - 0.00013 21.1 0.1 0.00023 20.3 0.1 1.4 2 0 0 2 2 2 1 Chlorophyllase DLH PF01738.18 KXH53159.1 - 0.00041 20.0 0.0 0.0073 15.9 0.0 2.2 2 0 0 2 2 2 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 KXH53159.1 - 0.003 16.9 0.0 0.011 15.1 0.0 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 KXH53159.1 - 0.0067 16.2 0.0 0.65 9.8 0.0 2.3 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_4 PF08386.10 KXH53159.1 - 0.023 14.8 0.0 0.081 13.1 0.0 1.9 2 0 0 2 2 2 0 TAP-like protein Peptidase_S15 PF02129.18 KXH53159.1 - 0.043 13.4 0.0 0.18 11.3 0.2 1.9 2 1 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Aminotran_1_2 PF00155.21 KXH53160.1 - 1.7e-39 136.0 0.0 2.1e-39 135.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DHDPS PF00701.22 KXH53161.1 - 5.1e-32 110.8 0.0 6e-32 110.5 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family DUF3425 PF11905.8 KXH53162.1 - 4e-12 46.2 0.0 8.3e-12 45.2 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 KXH53162.1 - 0.37 10.9 10.3 1.2 9.3 10.3 1.8 1 1 0 1 1 1 0 bZIP transcription factor Atg14 PF10186.9 KXH53162.1 - 1.9 7.5 7.0 2.9 6.9 7.0 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 ZapB PF06005.12 KXH53162.1 - 6.2 7.3 8.2 23 5.5 8.2 2.0 1 1 0 1 1 1 0 Cell division protein ZapB p450 PF00067.22 KXH53163.1 - 5.4e-60 203.4 0.0 7.7e-60 202.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.25 KXH53164.1 - 7.7e-21 74.4 0.0 1.1e-20 74.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXH53164.1 - 7.2e-14 51.9 0.0 9.4e-14 51.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH53164.1 - 0.0012 18.8 0.0 0.0014 18.6 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KXH53164.1 - 0.1 12.5 0.6 0.29 11.0 0.6 1.8 1 1 0 1 1 1 0 NAD(P)H-binding 4HBT_2 PF13279.6 KXH53165.1 - 3.4e-09 37.3 0.0 5e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily dTDP_sugar_isom PF00908.17 KXH53165.1 - 0.047 13.4 0.0 0.087 12.5 0.0 1.4 1 0 0 1 1 1 0 dTDP-4-dehydrorhamnose 3,5-epimerase PASTA PF03793.19 KXH53165.1 - 0.064 13.1 0.3 0.8 9.6 0.1 2.2 1 1 1 2 2 2 0 PASTA domain His_Phos_2 PF00328.22 KXH53166.1 - 2.1e-23 83.3 0.0 2.8e-23 82.9 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) FAD_binding_3 PF01494.19 KXH53167.1 - 2.9e-12 46.5 0.0 2.1e-05 23.9 0.0 3.0 3 0 0 3 3 3 2 FAD binding domain NAD_binding_8 PF13450.6 KXH53167.1 - 9.4e-05 22.6 0.1 0.00024 21.3 0.0 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXH53167.1 - 0.0066 15.7 0.1 0.04 13.1 0.1 2.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXH53167.1 - 0.17 12.5 0.0 0.31 11.6 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AA_permease_2 PF13520.6 KXH53168.1 - 2.8e-62 210.9 44.6 3.5e-62 210.6 44.6 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXH53168.1 - 4.8e-12 45.2 40.3 6.6e-12 44.8 40.3 1.1 1 0 0 1 1 1 1 Amino acid permease Rod_cone_degen PF15201.6 KXH53168.1 - 0.066 13.3 0.5 10 6.3 0.0 2.9 2 0 0 2 2 2 0 Progressive rod-cone degeneration PHO4 PF01384.20 KXH53170.1 - 7.9e-110 367.0 10.8 9.3e-110 366.8 10.8 1.0 1 0 0 1 1 1 1 Phosphate transporter family Tim17 PF02466.19 KXH53170.1 - 0.00081 19.7 1.3 0.0051 17.2 0.0 2.9 2 1 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family Glycophorin_A PF01102.18 KXH53170.1 - 0.024 14.9 0.1 0.06 13.6 0.1 1.6 1 0 0 1 1 1 0 Glycophorin A DUF2070 PF09843.9 KXH53170.1 - 2 6.6 10.2 3.5 5.8 10.2 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) FAD_binding_3 PF01494.19 KXH53171.1 - 4.8e-16 59.0 0.3 2.6e-15 56.5 0.3 1.9 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KXH53171.1 - 1.8e-08 34.5 0.5 4.5e-08 33.2 0.5 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXH53171.1 - 1.4e-06 28.1 4.1 2.4e-06 27.4 3.6 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXH53171.1 - 1.5e-06 27.7 0.3 2.5e-06 27.0 0.3 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KXH53171.1 - 6.6e-05 22.4 0.1 9.9e-05 21.9 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KXH53171.1 - 0.00013 22.4 1.3 0.00033 21.1 1.3 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KXH53171.1 - 0.00025 20.2 0.1 0.00035 19.7 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 KXH53171.1 - 0.0003 20.0 4.0 0.00089 18.4 3.2 1.8 1 1 1 2 2 2 1 FAD binding domain GIDA PF01134.22 KXH53171.1 - 0.0037 16.4 1.3 0.0054 15.9 1.3 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Amino_oxidase PF01593.24 KXH53171.1 - 0.0056 16.0 0.1 0.018 14.3 0.0 1.7 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase HI0933_like PF03486.14 KXH53171.1 - 0.022 13.5 1.2 0.032 12.9 1.2 1.2 1 0 0 1 1 1 0 HI0933-like protein Rossmann-like PF10727.9 KXH53171.1 - 0.042 13.7 0.4 0.092 12.6 0.4 1.5 1 0 0 1 1 1 0 Rossmann-like domain 3HCDH_N PF02737.18 KXH53171.1 - 0.049 13.5 1.6 0.094 12.6 1.6 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 KXH53171.1 - 0.091 12.9 0.2 0.21 11.7 0.2 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Pyr_redox_3 PF13738.6 KXH53171.1 - 0.12 11.6 0.4 0.21 10.8 0.4 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.23 KXH53171.1 - 0.13 12.2 0.5 0.29 11.1 0.5 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Trp_halogenase PF04820.14 KXH53171.1 - 0.2 10.4 0.7 0.59 8.9 0.7 1.7 2 0 0 2 2 2 0 Tryptophan halogenase AlaDh_PNT_C PF01262.21 KXH53171.1 - 0.29 10.4 1.2 0.53 9.5 1.2 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DUF4796 PF16044.5 KXH53172.1 - 0.056 13.0 0.0 0.092 12.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4796) MutS_III PF05192.18 KXH53172.1 - 0.071 13.3 0.1 0.12 12.6 0.1 1.3 1 0 0 1 1 1 0 MutS domain III LysM PF01476.20 KXH53174.1 - 0.0053 16.8 0.0 0.02 14.9 0.0 1.9 2 0 0 2 2 2 1 LysM domain HPP PF04982.13 KXH53174.1 - 0.039 14.1 0.1 0.12 12.5 0.1 1.9 1 0 0 1 1 1 0 HPP family Glyco_hydro_18 PF00704.28 KXH53175.1 - 5.3e-69 233.3 2.0 5.3e-69 233.3 2.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 KXH53175.1 - 2e-08 34.6 11.3 2e-08 34.6 11.3 3.7 6 0 0 6 6 6 1 Chitin recognition protein Glyco_hydro_85 PF03644.13 KXH53175.1 - 0.0011 18.5 0.1 0.0031 17.0 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 85 KASH_CCD PF14662.6 KXH53177.1 - 4.5e-06 26.6 75.3 0.00036 20.4 18.6 6.2 2 2 3 6 6 6 4 Coiled-coil region of CCDC155 or KASH APG6_N PF17675.1 KXH53177.1 - 5.7e-05 23.6 14.8 5.7e-05 23.6 14.8 6.3 3 3 3 6 6 6 1 Apg6 coiled-coil region HALZ PF02183.18 KXH53177.1 - 0.00022 21.4 46.7 0.051 13.8 0.0 10.9 8 4 4 12 12 11 3 Homeobox associated leucine zipper DUF3450 PF11932.8 KXH53177.1 - 0.00022 20.6 19.5 0.00031 20.1 5.9 6.8 3 3 3 6 6 6 3 Protein of unknown function (DUF3450) Spc7 PF08317.11 KXH53177.1 - 0.00035 19.6 16.0 0.00035 19.6 16.0 5.6 2 1 3 5 5 5 4 Spc7 kinetochore protein CENP-F_leu_zip PF10473.9 KXH53177.1 - 0.0021 18.1 13.5 0.0021 18.1 13.5 7.8 2 2 5 7 7 7 4 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Cep57_CLD_2 PF14197.6 KXH53177.1 - 0.0058 16.7 3.5 0.0058 16.7 3.5 8.3 5 3 2 7 7 5 1 Centrosome localisation domain of PPC89 Prp19 PF08606.11 KXH53177.1 - 0.019 15.0 0.2 9.3 6.3 0.0 3.6 2 1 0 2 2 2 0 Prp19/Pso4-like TSC22 PF01166.18 KXH53177.1 - 0.024 15.0 0.5 0.024 15.0 0.5 8.1 7 4 5 12 12 10 0 TSC-22/dip/bun family SHE3 PF17078.5 KXH53177.1 - 0.12 12.1 56.4 0.031 14.0 5.8 6.3 2 2 3 6 6 6 0 SWI5-dependent HO expression protein 3 HOOK PF05622.12 KXH53177.1 - 1.1 7.4 77.2 2.3 6.3 64.3 3.6 2 1 1 3 3 3 0 HOOK protein GAS PF13851.6 KXH53177.1 - 1.5 8.1 66.2 0.33 10.3 6.0 5.5 2 1 4 6 6 6 0 Growth-arrest specific micro-tubule binding TLE_N PF03920.15 KXH53177.1 - 3 7.9 10.2 23 5.1 4.7 4.2 2 1 0 2 2 2 0 Groucho/TLE N-terminal Q-rich domain DUF5082 PF16888.5 KXH53177.1 - 5.6 7.3 55.5 0.26 11.6 9.0 7.0 3 1 3 7 7 7 0 Domain of unknown function (DUF5082) CFEM PF05730.11 KXH53178.1 - 3.3e-12 46.3 12.0 1e-11 44.8 12.0 1.8 1 0 0 1 1 1 1 CFEM domain Gamma-thionin PF00304.20 KXH53178.1 - 0.025 14.8 0.6 0.044 14.0 0.6 1.4 1 0 0 1 1 1 0 Gamma-thionin family Cupin_1 PF00190.22 KXH53180.1 - 1.1e-40 138.7 0.0 9.2e-21 74.0 0.0 2.1 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 KXH53180.1 - 4.6e-26 90.3 0.7 2e-13 49.8 0.1 2.5 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.19 KXH53180.1 - 9.2e-08 32.1 0.2 0.00036 20.5 0.1 2.3 2 0 0 2 2 2 2 AraC-like ligand binding domain Cupin_3 PF05899.12 KXH53180.1 - 1.6e-07 30.9 0.0 0.013 15.2 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF861) MannoseP_isomer PF01050.18 KXH53180.1 - 0.00013 21.9 0.0 0.027 14.3 0.0 2.2 2 0 0 2 2 2 2 Mannose-6-phosphate isomerase ARD PF03079.14 KXH53180.1 - 0.00073 19.8 0.2 0.089 13.0 0.0 2.4 2 0 0 2 2 2 1 ARD/ARD' family 3-HAO PF06052.12 KXH53180.1 - 0.053 13.1 0.0 0.73 9.5 0.0 2.2 2 0 0 2 2 2 0 3-hydroxyanthranilic acid dioxygenase Cupin_7 PF12973.7 KXH53180.1 - 0.15 12.0 0.1 0.69 9.9 0.0 2.2 2 0 0 2 2 2 0 ChrR Cupin-like domain Sulfate_transp PF00916.20 KXH53181.1 - 3.7e-86 289.3 20.4 5.6e-86 288.7 20.4 1.3 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KXH53181.1 - 1.5e-12 47.2 0.0 2.7e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 STAS domain Synaptobrevin PF00957.21 KXH53182.1 - 0.0077 16.0 1.1 0.098 12.5 0.1 2.4 2 0 0 2 2 2 1 Synaptobrevin bZIP_1 PF00170.21 KXH53182.1 - 0.17 12.0 4.5 2.9 8.0 0.0 3.2 2 1 1 3 3 3 0 bZIP transcription factor DUF4472 PF14739.6 KXH53182.1 - 0.59 10.9 10.9 0.88 10.3 3.5 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) Nsp1_C PF05064.13 KXH53182.1 - 0.72 9.7 5.9 2.1 8.2 2.4 2.3 1 1 1 2 2 2 0 Nsp1-like C-terminal region PBECR5 PF18814.1 KXH53182.1 - 1.2 9.1 7.2 1.8 8.4 7.1 1.4 1 1 1 2 2 2 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease5 XhlA PF10779.9 KXH53182.1 - 2.7 8.3 6.2 10 6.4 0.7 2.7 2 2 1 3 3 3 0 Haemolysin XhlA HIP1_clath_bdg PF16515.5 KXH53183.1 - 0.056 14.1 5.7 0.66 10.6 1.6 2.0 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 LPD30 PF18850.1 KXH53183.1 - 0.097 12.4 0.7 0.12 12.1 0.7 1.3 1 0 0 1 1 1 0 Large polyvalent protein associated domain 30 Fungal_TACC PF12709.7 KXH53183.1 - 0.11 13.0 4.1 0.28 11.7 0.9 2.2 1 1 1 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins PHA_gran_rgn PF09650.10 KXH53183.1 - 0.13 12.6 1.8 0.37 11.1 0.2 2.0 1 1 1 2 2 2 0 Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) TMPIT PF07851.13 KXH53183.1 - 0.28 10.4 1.1 0.32 10.2 1.1 1.1 1 0 0 1 1 1 0 TMPIT-like protein FAM184 PF15665.5 KXH53183.1 - 0.33 10.7 8.5 1.3 8.7 8.5 1.7 1 1 0 1 1 1 0 Family with sequence similarity 184, A and B DUF4527 PF15030.6 KXH53184.1 - 0.018 14.5 6.8 0.03 13.8 6.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4527) UDPGT PF00201.18 KXH53184.1 - 0.064 12.0 2.8 0.077 11.8 2.8 1.1 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase DXP_redisom_C PF08436.12 KXH53184.1 - 0.16 12.1 0.2 0.53 10.5 0.0 1.9 2 1 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal domain Caudo_TAP PF02413.17 KXH53184.1 - 0.16 12.1 7.3 0.047 13.8 4.4 1.6 2 0 0 2 2 2 0 Caudovirales tail fibre assembly protein, lambda gpK TolA_bind_tri PF16331.5 KXH53184.1 - 0.23 11.5 10.0 4.4 7.4 7.1 2.2 1 1 1 2 2 2 0 TolA binding protein trimerisation DUF2570 PF10828.8 KXH53184.1 - 5.5 6.9 13.6 5.1 7.0 11.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2570) DUF1043 PF06295.12 KXH53184.1 - 5.8 6.9 12.5 0.2 11.7 5.9 1.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1043) Nop52 PF05997.12 KXH53185.1 - 7.4e-59 199.2 0.5 9.6e-59 198.8 0.5 1.1 1 0 0 1 1 1 1 Nucleolar protein,Nop52 DUF416 PF04222.12 KXH53185.1 - 0.18 11.2 2.6 0.13 11.6 0.7 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF416) DAGK_cat PF00781.24 KXH53186.1 - 4.7e-25 87.6 0.0 1.4e-24 86.1 0.0 1.8 2 0 0 2 2 2 1 Diacylglycerol kinase catalytic domain Glycos_trans_3N PF02885.17 KXH53187.1 - 4.5e-10 39.2 0.0 5.8e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain Glyco_transf_28 PF03033.20 KXH53205.1 - 3.6e-17 62.7 0.0 1.1e-16 61.2 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 KXH53205.1 - 0.0035 16.2 0.0 0.006 15.4 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase VPS13_C PF16909.5 KXH53205.1 - 0.0045 16.8 0.1 0.012 15.4 0.1 1.7 1 0 0 1 1 1 1 Vacuolar-sorting-associated 13 protein C-terminal Glyco_tran_28_C PF04101.16 KXH53205.1 - 0.028 14.4 0.0 0.055 13.4 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain ATG_C PF09333.11 KXH53205.1 - 0.036 14.4 0.1 0.18 12.2 0.0 2.2 2 0 0 2 2 2 0 Autophagy-related protein C terminal domain PSRT PF07636.11 KXH53205.1 - 0.2 11.4 0.8 0.48 10.2 0.8 1.6 1 0 0 1 1 1 0 PSRT MARVEL PF01284.23 KXH53206.1 - 2.9e-07 30.6 13.4 4.3e-07 30.0 13.4 1.3 1 0 0 1 1 1 1 Membrane-associating domain FAD_binding_4 PF01565.23 KXH53207.1 - 2.6e-24 85.5 2.3 5.5e-24 84.5 2.3 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KXH53207.1 - 2e-07 31.0 0.2 4.4e-07 29.9 0.2 1.5 1 0 0 1 1 1 1 Berberine and berberine like Cir_N PF10197.9 KXH53208.1 - 8.8e-09 35.4 3.5 8.8e-09 35.4 3.5 2.9 2 0 0 2 2 2 1 N-terminal domain of CBF1 interacting co-repressor CIR AAA PF00004.29 KXH53209.1 - 2.7e-50 170.2 0.0 1.2e-37 129.2 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KXH53209.1 - 9.1e-10 38.2 0.1 2.5e-09 36.8 0.1 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 KXH53209.1 - 4.7e-08 33.4 0.0 0.00037 20.8 0.0 3.8 2 2 0 2 2 2 1 AAA domain TIP49 PF06068.13 KXH53209.1 - 4.2e-07 29.5 0.0 0.022 14.0 0.0 2.4 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_16 PF13191.6 KXH53209.1 - 7e-07 29.8 0.0 0.04 14.3 0.0 3.0 2 1 0 2 2 2 2 AAA ATPase domain AAA_14 PF13173.6 KXH53209.1 - 1.3e-06 28.5 0.0 0.021 14.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain ATPase_2 PF01637.18 KXH53209.1 - 3.2e-06 27.2 0.1 1.5 8.7 0.0 4.2 2 2 1 4 4 4 1 ATPase domain predominantly from Archaea AAA_2 PF07724.14 KXH53209.1 - 4.2e-06 27.0 0.0 5.5e-05 23.3 0.1 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 KXH53209.1 - 5e-06 26.5 0.0 0.0022 18.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 KXH53209.1 - 2.5e-05 23.7 0.1 0.0041 16.5 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 KXH53209.1 - 3.8e-05 24.2 0.0 0.015 15.9 0.0 2.9 3 0 0 3 3 2 1 AAA domain RuvB_N PF05496.12 KXH53209.1 - 7.6e-05 22.5 0.2 0.062 13.0 0.1 2.9 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 KXH53209.1 - 8.7e-05 22.1 0.1 0.015 14.9 0.0 2.6 3 0 0 3 3 2 1 P-loop containing dynein motor region AAA_24 PF13479.6 KXH53209.1 - 9.5e-05 22.2 0.0 0.033 13.9 0.0 2.7 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KXH53209.1 - 9.7e-05 22.7 0.0 0.29 11.6 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA_33 PF13671.6 KXH53209.1 - 0.00028 21.1 0.0 0.34 11.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 KXH53209.1 - 0.0003 20.6 0.0 0.038 13.7 0.0 3.3 3 0 0 3 3 3 1 IstB-like ATP binding protein ATPase PF06745.13 KXH53209.1 - 0.0027 17.1 0.1 0.13 11.6 0.1 2.7 2 0 0 2 2 2 1 KaiC TsaE PF02367.17 KXH53209.1 - 0.0039 17.2 0.0 0.48 10.4 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 KXH53209.1 - 0.0061 16.2 0.1 4.1 6.9 0.1 2.7 2 1 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 KXH53209.1 - 0.0086 15.8 0.0 0.73 9.5 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_19 PF13245.6 KXH53209.1 - 0.011 16.1 0.1 0.42 10.9 0.1 2.8 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KXH53209.1 - 0.012 16.2 0.1 0.06 13.9 0.1 2.2 2 1 0 2 2 1 0 ABC transporter NACHT PF05729.12 KXH53209.1 - 0.014 15.3 0.6 16 5.4 0.0 3.6 3 1 0 3 3 2 0 NACHT domain AAA_11 PF13086.6 KXH53209.1 - 0.016 15.0 0.0 1.4 8.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain CPT PF07931.12 KXH53209.1 - 0.019 14.8 0.0 0.32 10.8 0.0 2.4 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein NB-ARC PF00931.22 KXH53209.1 - 0.029 13.6 0.1 4.8 6.3 0.1 2.8 3 0 0 3 3 3 0 NB-ARC domain TniB PF05621.11 KXH53209.1 - 0.049 13.0 0.1 6.6 6.1 0.0 3.4 2 1 1 3 3 3 0 Bacterial TniB protein KTI12 PF08433.10 KXH53209.1 - 0.053 13.0 0.0 1.6 8.1 0.0 2.4 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_3 PF07726.11 KXH53209.1 - 0.054 13.3 0.0 0.5 10.2 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.17 KXH53209.1 - 0.061 12.4 0.0 1.6 7.8 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 PhoH PF02562.16 KXH53209.1 - 0.069 12.6 0.0 1 8.8 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein AAA_28 PF13521.6 KXH53209.1 - 0.12 12.6 0.0 0.82 9.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain CDC48_2 PF02933.17 KXH53209.1 - 0.16 11.8 0.7 3.9 7.3 0.1 2.5 2 0 0 2 2 2 0 Cell division protein 48 (CDC48), domain 2 Vps4_C PF09336.10 KXH53209.1 - 0.17 11.9 0.0 0.66 10.0 0.0 2.0 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain YukD PF08817.10 KXH53210.1 - 0.00088 19.9 0.0 0.0013 19.3 0.0 1.3 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukD ubiquitin PF00240.23 KXH53210.1 - 0.0069 16.1 0.0 0.011 15.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family DNA_binding_1 PF01035.20 KXH53211.1 - 8.4e-30 102.7 0.0 1.2e-29 102.2 0.0 1.2 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain SO_alpha_A3 PF17806.1 KXH53211.1 - 0.13 12.6 0.0 0.23 11.8 0.0 1.4 1 0 0 1 1 1 0 Sarcosine oxidase A3 domain PHO4 PF01384.20 KXH53380.1 - 3.3e-112 374.9 17.4 3.9e-112 374.6 17.4 1.1 1 0 0 1 1 1 1 Phosphate transporter family Meiotic_rec114 PF03525.14 KXH53380.1 - 0.078 11.9 0.6 0.12 11.3 0.6 1.2 1 0 0 1 1 1 0 Meiotic recombination protein rec114 HET PF06985.11 KXH53381.1 - 4.1e-30 105.1 0.0 7.6e-30 104.2 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) T2SSM PF04612.12 KXH53381.1 - 0.09 12.8 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M FA_desaturase PF00487.24 KXH53382.1 - 5.2e-32 111.7 19.1 7.7e-32 111.1 19.1 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 KXH53382.1 - 1.1e-09 38.3 0.0 2.5e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain HET PF06985.11 KXH53383.1 - 1e-24 87.5 0.0 9e-24 84.5 0.0 2.4 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Glyco_hydro_7 PF00840.20 KXH53384.1 - 6.3e-140 466.7 12.8 7.9e-140 466.4 12.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 GMC_oxred_N PF00732.19 KXH53385.1 - 7.8e-49 166.6 0.3 5.7e-30 104.7 0.0 2.8 2 1 1 3 3 3 2 GMC oxidoreductase GMC_oxred_C PF05199.13 KXH53385.1 - 2.3e-32 112.5 0.1 3.4e-32 111.9 0.1 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KXH53385.1 - 1e-05 24.8 0.1 1.7e-05 24.1 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein GIDA PF01134.22 KXH53385.1 - 0.0038 16.4 0.0 0.054 12.6 0.0 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 KXH53385.1 - 0.023 14.9 0.0 0.065 13.5 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXH53385.1 - 0.031 13.5 0.0 0.053 12.7 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXH53385.1 - 0.16 11.9 0.1 0.36 10.8 0.1 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Sugar_tr PF00083.24 KXH53388.1 - 2.3e-100 336.6 30.0 2.9e-100 336.3 30.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH53388.1 - 7.3e-21 74.5 34.2 7.3e-21 74.5 34.2 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily PsaL PF02605.15 KXH53388.1 - 0.082 12.6 2.2 0.13 11.9 0.3 2.3 2 0 0 2 2 2 0 Photosystem I reaction centre subunit XI Glyco_hydro_32N PF00251.20 KXH53389.1 - 9.5e-31 107.5 6.8 4.2e-20 72.5 2.8 2.2 2 0 0 2 2 2 2 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 KXH53389.1 - 1.3e-30 106.5 0.3 2.2e-30 105.8 0.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal DUF4975 PF16346.5 KXH53389.1 - 0.00012 22.2 0.0 0.00021 21.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4975) DUF3292 PF11696.8 KXH53390.1 - 4.5e-281 933.9 0.1 4.5e-281 933.9 0.1 2.7 2 1 0 2 2 2 1 Protein of unknown function (DUF3292) Pex24p PF06398.11 KXH53390.1 - 0.0042 16.1 0.0 0.0059 15.6 0.0 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin MFS_1 PF07690.16 KXH53391.1 - 3.3e-26 92.0 26.3 3.3e-26 92.0 26.3 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily APH PF01636.23 KXH53392.1 - 3.2e-09 37.1 0.9 3.2e-08 33.8 0.7 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KXH53392.1 - 0.12 11.9 0.0 1.5 8.4 0.0 2.1 2 0 0 2 2 2 0 Choline/ethanolamine kinase RNA_pol_Rpb1_4 PF05000.17 KXH53393.1 - 0.015 15.2 1.0 0.019 14.9 0.2 1.6 2 0 0 2 2 2 0 RNA polymerase Rpb1, domain 4 cwf18 PF08315.12 KXH53393.1 - 0.023 15.4 5.7 0.026 15.2 5.7 1.2 1 0 0 1 1 1 0 cwf18 pre-mRNA splicing factor DUF3292 PF11696.8 KXH53393.1 - 0.1 10.9 4.4 0.11 10.8 4.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) HisK_sensor PF18698.1 KXH53393.1 - 0.31 11.4 4.1 0.35 11.3 4.1 1.1 1 0 0 1 1 1 0 Histidine kinase sensor domain DUF4246 PF14033.6 KXH53395.1 - 2e-169 564.5 0.0 2.5e-169 564.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) Nop14 PF04147.12 KXH53395.1 - 0.013 13.7 7.5 0.018 13.3 7.5 1.2 1 0 0 1 1 1 0 Nop14-like family Cwf_Cwc_15 PF04889.12 KXH53395.1 - 0.33 10.7 16.5 0.61 9.8 16.5 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RNA_pol_3_Rpc31 PF11705.8 KXH53395.1 - 1.3 9.2 17.4 3 8.0 17.4 1.6 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DUF2457 PF10446.9 KXH53395.1 - 2.4 7.2 21.5 0.94 8.5 18.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) BUD22 PF09073.10 KXH53395.1 - 4.6 6.5 13.4 7.7 5.7 13.4 1.3 1 0 0 1 1 1 0 BUD22 NmrA PF05368.13 KXH53399.1 - 5.7e-27 94.8 0.0 8e-27 94.3 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXH53399.1 - 4.4e-11 43.0 0.1 5.7e-11 42.6 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 KXH53399.1 - 0.001 19.0 0.0 0.0075 16.2 0.0 2.0 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KXH53399.1 - 0.015 14.7 0.0 0.072 12.5 0.0 1.8 1 1 1 2 2 2 0 NAD dependent epimerase/dehydratase family DUF442 PF04273.13 KXH53400.1 - 0.021 14.9 0.2 0.031 14.3 0.2 1.2 1 0 0 1 1 1 0 Putative phosphatase (DUF442) Zn_clus PF00172.18 KXH53402.1 - 9.6e-07 28.8 11.2 1.9e-06 27.9 11.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXH53402.1 - 8.8e-06 24.9 0.1 1.4e-05 24.3 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF678 PF05077.12 KXH53404.1 - 0.051 13.7 0.2 0.14 12.3 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF678) Pro_Al_protease PF02983.14 KXH53406.1 - 0.18 11.9 1.3 6.6 6.9 0.2 2.3 2 0 0 2 2 2 0 Alpha-lytic protease prodomain adh_short PF00106.25 KXH53407.1 - 3.7e-43 147.3 0.1 4.6e-43 147.0 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXH53407.1 - 1.5e-42 145.7 0.0 1.4e-37 129.5 0.0 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH53407.1 - 3.9e-13 49.7 0.0 6.3e-13 49.0 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXH53407.1 - 0.0002 20.9 0.0 0.00074 19.0 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DFP PF04127.15 KXH53407.1 - 0.025 14.4 0.5 1.1 9.0 0.4 2.2 1 1 1 2 2 2 0 DNA / pantothenate metabolism flavoprotein 3HCDH_N PF02737.18 KXH53407.1 - 0.054 13.4 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 KXH53407.1 - 0.079 12.1 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF1776 PF08643.10 KXH53407.1 - 0.081 12.3 0.0 0.085 12.2 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) GDP_Man_Dehyd PF16363.5 KXH53407.1 - 0.11 11.8 0.0 0.4 10.0 0.0 2.0 2 1 0 2 2 2 0 GDP-mannose 4,6 dehydratase Tri3 PF07428.11 KXH53409.1 - 6.6e-107 357.9 0.0 9.8e-107 357.4 0.0 1.2 1 0 0 1 1 1 1 15-O-acetyltransferase Tri3 AATase PF07247.12 KXH53409.1 - 8.4e-08 31.2 0.0 1.1e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 Alcohol acetyltransferase Sugar_tr PF00083.24 KXH53410.1 - 1.1e-78 265.2 24.8 1.3e-78 264.9 24.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH53410.1 - 4.6e-25 88.3 30.6 1.6e-19 70.1 17.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KXH53410.1 - 0.0055 15.0 0.4 0.0055 15.0 0.4 2.4 2 1 1 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family HET PF06985.11 KXH53411.1 - 9.8e-23 81.1 0.4 1.6e-21 77.2 0.0 2.8 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) ADH_zinc_N PF00107.26 KXH53413.1 - 6.9e-22 77.8 1.5 2.3e-21 76.1 1.5 1.9 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXH53413.1 - 2.9e-20 72.2 3.7 2.7e-19 69.0 2.0 2.7 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KXH53413.1 - 1.5e-10 42.2 0.0 1.6e-09 38.9 0.0 2.4 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KXH53413.1 - 2.7e-06 27.0 2.0 4.1e-06 26.4 2.0 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus NAD_binding_2 PF03446.15 KXH53413.1 - 1.2e-05 25.5 0.3 2.2e-05 24.7 0.3 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AlaDh_PNT_C PF01262.21 KXH53413.1 - 0.00018 20.9 5.0 0.00027 20.3 4.2 1.5 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 KXH53413.1 - 0.0005 19.7 0.2 0.0012 18.5 0.1 1.7 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.19 KXH53413.1 - 0.02 14.3 0.1 0.032 13.6 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 KXH53413.1 - 0.036 14.0 0.5 0.061 13.2 0.4 1.5 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PDH PF02153.17 KXH53413.1 - 0.089 11.8 0.1 0.15 11.0 0.1 1.4 1 1 0 1 1 1 0 Prephenate dehydrogenase Porphobil_deamC PF03900.15 KXH53413.1 - 0.09 13.2 0.1 14 6.1 0.1 2.6 2 0 0 2 2 2 0 Porphobilinogen deaminase, C-terminal domain Sugar_tr PF00083.24 KXH53414.1 - 7.6e-86 288.7 22.0 8.7e-86 288.5 22.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH53414.1 - 3.8e-18 65.5 37.0 7.8e-11 41.5 15.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Romo1 PF10247.9 KXH53414.1 - 2 8.8 6.6 6.1 7.3 0.0 3.2 3 0 0 3 3 3 0 Reactive mitochondrial oxygen species modulator 1 DUF2183 PF09949.9 KXH53415.1 - 2.1e-33 114.6 0.1 8.2e-33 112.7 0.0 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2183) Fungal_trans_2 PF11951.8 KXH53417.1 - 3.4e-26 91.9 0.0 1.7e-12 46.9 0.0 2.1 1 1 1 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH53417.1 - 1.8e-05 24.8 8.1 3.4e-05 23.9 8.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAH PF02671.21 KXH53418.1 - 0.00014 21.9 0.2 0.00031 20.8 0.1 1.6 2 0 0 2 2 2 1 Paired amphipathic helix repeat OST-HTH PF12872.7 KXH53418.1 - 0.019 14.8 0.1 0.059 13.2 0.0 1.8 2 0 0 2 2 2 0 OST-HTH/LOTUS domain Amino_oxidase PF01593.24 KXH53419.1 - 5.8e-49 167.6 0.1 6.6e-49 167.4 0.1 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KXH53419.1 - 3.3e-12 46.5 0.2 8.4e-12 45.2 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KXH53419.1 - 2.5e-09 37.0 1.0 4.6e-09 36.1 0.8 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KXH53419.1 - 8.9e-09 34.9 2.5 1.5e-08 34.2 2.5 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KXH53419.1 - 3.1e-08 33.6 0.2 1.4e-07 31.4 0.2 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KXH53419.1 - 1.1e-06 27.6 0.7 1.4e-06 27.3 0.1 1.5 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 KXH53419.1 - 1.6e-06 27.6 0.5 2.5e-06 26.9 0.5 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 KXH53419.1 - 8.9e-06 25.1 0.7 1.4e-05 24.5 0.7 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KXH53419.1 - 9.6e-06 24.9 0.2 1.7e-05 24.1 0.2 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.27 KXH53419.1 - 1.6e-05 25.4 0.5 0.0002 21.8 0.2 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXH53419.1 - 3.6e-05 23.2 0.7 0.0011 18.3 0.2 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KXH53419.1 - 0.00013 21.2 1.1 0.0005 19.2 1.1 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 KXH53419.1 - 0.00066 19.0 0.4 0.0013 18.1 0.4 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 KXH53419.1 - 0.0012 18.2 0.6 0.003 16.9 0.6 1.7 1 0 0 1 1 1 1 FAD binding domain 3HCDH_N PF02737.18 KXH53419.1 - 0.041 13.8 0.1 0.086 12.7 0.1 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FMO-like PF00743.19 KXH53419.1 - 0.12 10.7 0.0 0.46 8.8 0.0 1.8 1 1 1 2 2 2 0 Flavin-binding monooxygenase-like MFS_1 PF07690.16 KXH53420.1 - 1.1e-30 106.8 15.3 1.1e-30 106.8 15.3 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily CbtA PF09490.10 KXH53420.1 - 0.044 13.6 3.2 3.3 7.4 1.6 2.9 3 0 0 3 3 3 0 Probable cobalt transporter subunit (CbtA) MgtC PF02308.16 KXH53420.1 - 0.051 14.0 3.0 1.7 9.0 0.0 2.7 3 0 0 3 3 3 0 MgtC family FMO-like PF00743.19 KXH53421.1 - 9.3e-26 90.3 0.0 4.3e-18 65.1 0.0 3.1 2 1 1 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KXH53421.1 - 6.2e-10 38.8 0.0 1.8e-08 34.0 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXH53421.1 - 9.1e-07 28.3 0.0 0.00011 21.5 0.0 2.9 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KXH53421.1 - 2.3e-06 27.1 0.0 4.1e-05 23.0 0.0 2.4 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXH53421.1 - 0.0044 17.0 0.3 0.026 14.5 0.1 2.4 2 1 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KXH53421.1 - 0.022 15.0 0.0 0.094 13.0 0.0 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KXH53421.1 - 0.15 11.3 0.1 0.36 10.0 0.0 1.5 2 0 0 2 2 2 0 Thi4 family p450 PF00067.22 KXH53423.1 - 1.2e-40 139.7 0.0 1.5e-40 139.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ORF6C PF10552.9 KXH53423.1 - 0.072 13.2 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 ORF6C domain FAD_binding_4 PF01565.23 KXH53424.1 - 8.2e-25 87.2 4.6 1.9e-24 86.0 4.6 1.7 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KXH53424.1 - 0.024 14.7 0.1 0.05 13.7 0.1 1.5 1 0 0 1 1 1 0 Berberine and berberine like polyprenyl_synt PF00348.17 KXH53425.1 - 9.7e-51 172.3 0.0 1.9e-50 171.3 0.0 1.4 1 0 0 1 1 1 1 Polyprenyl synthetase p450 PF00067.22 KXH53426.1 - 5.7e-65 219.8 0.0 7.3e-65 219.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF4105 PF13387.6 KXH53427.1 - 0.00049 19.8 0.2 0.00073 19.2 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4105) DUF778 PF05608.12 KXH53427.1 - 0.00052 20.4 0.0 0.0011 19.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF778) Peptidase_C97 PF05903.14 KXH53427.1 - 0.00077 19.3 0.0 0.0012 18.7 0.0 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.13 KXH53427.1 - 0.044 14.1 0.6 0.59 10.5 0.1 2.3 1 1 0 2 2 2 0 Lecithin retinol acyltransferase p450 PF00067.22 KXH53428.1 - 4.9e-64 216.8 0.0 5.7e-64 216.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 RasGEF PF00617.19 KXH53429.1 - 6e-52 176.4 0.0 1.3e-51 175.4 0.0 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KXH53429.1 - 1e-14 54.6 0.0 3.5e-14 52.9 0.0 1.9 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_9 PF14604.6 KXH53429.1 - 3e-06 27.0 0.0 5.4e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KXH53429.1 - 3.7e-05 23.2 0.0 7e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 SH3 domain Jacalin PF01419.17 KXH53432.1 - 0.02 14.8 0.0 0.034 14.1 0.0 1.4 1 0 0 1 1 1 0 Jacalin-like lectin domain Peptidase_C97 PF05903.14 KXH53434.1 - 0.046 13.6 0.0 0.07 13.0 0.0 1.3 1 0 0 1 1 1 0 PPPDE putative peptidase domain Aldedh PF00171.22 KXH53435.1 - 1.3e-147 492.0 0.0 1.6e-147 491.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KXH53435.1 - 0.17 10.9 0.0 0.28 10.2 0.0 1.4 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) Peptidase_C14 PF00656.22 KXH53437.1 - 2.5e-17 63.7 0.0 3.7e-17 63.1 0.0 1.2 1 0 0 1 1 1 1 Caspase domain CHAT PF12770.7 KXH53438.1 - 1e-34 120.3 0.0 2e-34 119.4 0.0 1.4 1 0 0 1 1 1 1 CHAT domain TPR_10 PF13374.6 KXH53438.1 - 1.1e-10 41.0 23.7 0.4 10.6 0.1 14.5 16 2 0 16 16 16 4 Tetratricopeptide repeat TPR_12 PF13424.6 KXH53438.1 - 1.7e-09 37.8 12.3 0.23 11.8 0.0 9.4 7 3 3 10 10 10 3 Tetratricopeptide repeat TPR_8 PF13181.6 KXH53438.1 - 8.5e-06 25.6 10.3 85 3.8 0.0 11.6 14 0 0 14 14 14 0 Tetratricopeptide repeat Peptidase_C50 PF03568.17 KXH53438.1 - 0.015 14.4 0.0 0.057 12.5 0.0 2.0 1 1 0 1 1 1 0 Peptidase family C50 SMBP PF16785.5 KXH53438.1 - 0.021 15.0 5.3 13 6.1 0.0 6.0 7 0 0 7 7 7 0 Small metal-binding protein DUF4404 PF14357.6 KXH53438.1 - 0.13 12.9 9.7 1.3 9.7 0.1 4.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4404) TPR_16 PF13432.6 KXH53438.1 - 0.22 12.2 5.2 69 4.2 0.0 5.8 7 0 0 7 7 7 0 Tetratricopeptide repeat Fib_alpha PF08702.10 KXH53438.1 - 0.37 11.0 2.2 16 5.7 0.2 3.8 4 0 0 4 4 4 0 Fibrinogen alpha/beta chain family ZapA PF05164.13 KXH53438.1 - 1.5 9.3 9.4 1.4 9.4 0.1 4.6 4 1 1 5 5 5 0 Cell division protein ZapA adh_short PF00106.25 KXH53439.1 - 6e-31 107.4 0.2 1e-30 106.7 0.0 1.4 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXH53439.1 - 7.9e-22 78.0 0.4 1.2e-21 77.3 0.4 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KXH53439.1 - 0.00076 19.0 0.0 0.001 18.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KXH53439.1 - 0.017 15.0 0.8 0.45 10.4 0.8 2.7 1 1 0 1 1 1 0 KR domain Eno-Rase_NADH_b PF12242.8 KXH53439.1 - 0.2 11.4 0.8 0.58 9.9 0.3 2.0 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase adh_short_C2 PF13561.6 KXH53440.1 - 3.8e-54 183.7 4.7 5.2e-54 183.3 4.7 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXH53440.1 - 3.6e-48 163.6 2.6 7.1e-48 162.7 2.6 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXH53440.1 - 2e-10 40.9 0.3 3.3e-10 40.1 0.3 1.3 1 0 0 1 1 1 1 KR domain Hydantoinase_B PF02538.14 KXH53442.1 - 8e-185 615.1 0.8 1.1e-184 614.7 0.8 1.2 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 KXH53442.1 - 1.7e-92 309.8 0.0 3.3e-92 308.9 0.0 1.5 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 KXH53442.1 - 8.5e-52 175.4 0.0 3.8e-49 166.8 0.0 2.6 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region Proteasome_A_N PF10584.9 KXH53442.1 - 0.038 13.7 0.0 0.092 12.4 0.0 1.7 1 0 0 1 1 1 0 Proteasome subunit A N-terminal signature RsgI_N PF12791.7 KXH53442.1 - 0.11 12.5 0.1 4.6 7.2 0.1 3.0 3 0 0 3 3 3 0 Anti-sigma factor N-terminus MFS_1 PF07690.16 KXH53443.1 - 1.1e-20 73.9 26.5 1.9e-20 73.1 26.5 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 KXH53443.1 - 2.5e-12 46.8 6.6 2.5e-12 46.8 6.6 3.0 5 0 0 5 5 5 1 Ion channel regulatory protein UNC-93 7TM_GPCR_Sri PF10327.9 KXH53443.1 - 0.94 8.6 4.9 0.1 11.8 0.5 1.6 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Sri Thioredoxin PF00085.20 KXH53444.1 - 3.4e-23 81.6 0.0 5.4e-23 80.9 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 KXH53444.1 - 1.3e-05 24.8 0.6 1.4e-05 24.7 0.0 1.4 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 KXH53444.1 - 5.2e-05 23.6 0.6 0.00029 21.2 0.5 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Redoxin PF08534.10 KXH53444.1 - 0.00035 20.3 0.1 0.0006 19.5 0.1 1.4 1 1 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 KXH53444.1 - 0.00035 20.5 0.0 0.0042 17.0 0.0 2.0 1 1 1 2 2 2 1 AhpC/TSA family Thioredoxin_8 PF13905.6 KXH53444.1 - 0.00059 20.1 0.0 0.0029 17.9 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_7 PF13899.6 KXH53444.1 - 0.0012 19.0 0.0 0.0022 18.1 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like TraF PF13728.6 KXH53444.1 - 0.0077 16.1 0.0 0.011 15.6 0.0 1.2 1 0 0 1 1 1 1 F plasmid transfer operon protein HyaE PF07449.11 KXH53444.1 - 0.012 15.5 0.0 0.02 14.8 0.0 1.5 1 1 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Thioredoxin_9 PF14595.6 KXH53444.1 - 0.023 14.5 0.0 0.031 14.1 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Sulfotransfer_4 PF17784.1 KXH53445.1 - 1.3e-55 188.5 0.0 1.5e-55 188.3 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KXH53445.1 - 0.055 13.8 0.0 3.8 7.8 0.0 2.4 2 0 0 2 2 2 0 Sulfotransferase family AA_permease PF00324.21 KXH53446.1 - 6.9e-92 308.5 39.6 8.4e-92 308.2 39.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KXH53446.1 - 6e-25 87.9 40.2 7.5e-25 87.6 40.2 1.1 1 0 0 1 1 1 1 Amino acid permease p450 PF00067.22 KXH53448.1 - 1.9e-69 234.6 0.0 2.4e-69 234.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 GH131_N PF18271.1 KXH53449.1 - 6.3e-73 245.6 0.1 7.1e-73 245.4 0.1 1.0 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain Cutinase PF01083.22 KXH53450.1 - 4.8e-29 101.6 6.6 6.6e-29 101.1 6.6 1.2 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 KXH53450.1 - 0.00053 19.6 0.3 0.00067 19.3 0.3 1.2 1 0 0 1 1 1 1 PE-PPE domain Palm_thioest PF02089.15 KXH53450.1 - 0.0073 16.2 0.5 0.0078 16.1 0.5 1.1 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Lipase_3 PF01764.25 KXH53450.1 - 0.0087 15.9 0.2 0.012 15.5 0.2 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_1 PF00561.20 KXH53450.1 - 0.014 15.0 0.1 0.018 14.7 0.1 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 KXH53450.1 - 0.026 14.3 0.0 0.036 13.9 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase MFS_1 PF07690.16 KXH53451.1 - 1.3e-36 126.3 27.0 1.3e-36 126.3 27.0 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily zf-RING_6 PF14835.6 KXH53451.1 - 0.44 10.4 2.2 2.2 8.2 0.2 2.4 2 0 0 2 2 2 0 zf-RING of BARD1-type protein Abhydrolase_1 PF00561.20 KXH53452.1 - 1.5e-24 87.0 0.2 3e-17 63.1 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXH53452.1 - 1.2e-20 73.8 0.1 3.1e-13 49.6 0.1 2.0 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KXH53452.1 - 5e-18 66.5 0.0 6.6e-18 66.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KXH53452.1 - 6.7e-08 32.3 0.0 0.01 15.3 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Ndr PF03096.14 KXH53452.1 - 1.7e-06 26.9 0.0 2.1e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Ndr family Abhydrolase_4 PF08386.10 KXH53452.1 - 0.00036 20.6 0.0 0.00079 19.5 0.0 1.5 2 0 0 2 2 1 1 TAP-like protein Abhydrolase_3 PF07859.13 KXH53452.1 - 0.00059 19.8 0.0 0.0019 18.1 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold FSH1 PF03959.13 KXH53452.1 - 0.001 18.8 0.0 0.0013 18.5 0.0 1.5 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.7 KXH53452.1 - 0.0018 18.0 0.0 1 9.1 0.0 2.3 2 0 0 2 2 2 2 Alpha/beta hydrolase family DUF2920 PF11144.8 KXH53452.1 - 0.0075 15.5 0.0 0.011 14.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2920) AXE1 PF05448.12 KXH53452.1 - 0.011 14.4 0.3 1.9 7.1 0.0 2.9 2 1 1 3 3 3 0 Acetyl xylan esterase (AXE1) UPF0227 PF05728.12 KXH53452.1 - 0.05 13.5 0.0 0.12 12.3 0.0 1.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) Thioesterase PF00975.20 KXH53452.1 - 0.13 12.3 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain BAAT_C PF08840.11 KXH53452.1 - 0.14 12.1 0.0 0.32 10.9 0.0 1.6 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal adh_short PF00106.25 KXH53454.1 - 5e-34 117.5 0.0 6.8e-34 117.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXH53454.1 - 4.9e-24 85.2 0.0 1.3e-23 83.8 0.0 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KXH53454.1 - 0.0035 16.8 0.0 0.011 15.2 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KXH53454.1 - 0.037 13.9 0.0 0.079 12.9 0.0 1.5 1 0 0 1 1 1 0 KR domain Fungal_trans PF04082.18 KXH53455.1 - 2.9e-27 95.4 0.0 4e-27 94.9 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH53455.1 - 1.8e-06 28.0 8.3 3.2e-06 27.2 8.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FMO-like PF00743.19 KXH53456.1 - 3e-36 124.9 0.0 1.5e-20 73.1 0.0 3.0 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KXH53456.1 - 7.6e-16 58.2 0.1 9.9e-10 38.2 0.0 3.2 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXH53456.1 - 9.3e-14 51.3 0.0 1.4e-12 47.5 0.0 2.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXH53456.1 - 2.8e-09 37.1 0.0 8.6e-08 32.3 0.0 2.6 2 1 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.17 KXH53456.1 - 4.9e-08 32.5 0.1 9.8e-06 25.0 0.0 2.2 2 0 0 2 2 2 2 Thi4 family DAO PF01266.24 KXH53456.1 - 1.6e-07 31.3 0.0 0.0059 16.2 0.0 3.1 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXH53456.1 - 2e-07 31.1 0.0 4.8e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KXH53456.1 - 5.8e-07 29.0 0.0 0.00053 19.2 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 KXH53456.1 - 0.00018 22.0 0.0 0.026 15.1 0.0 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KXH53456.1 - 0.0027 17.1 0.0 0.004 16.6 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 KXH53456.1 - 0.0055 16.1 0.0 0.011 15.1 0.0 1.5 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase HI0933_like PF03486.14 KXH53456.1 - 0.014 14.1 0.0 0.026 13.2 0.0 1.6 1 1 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.19 KXH53456.1 - 0.02 14.2 0.0 0.041 13.1 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain Shikimate_DH PF01488.20 KXH53456.1 - 0.095 12.8 0.0 1.1 9.3 0.0 2.6 4 0 0 4 4 4 0 Shikimate / quinate 5-dehydrogenase Glu_dehyd_C PF16912.5 KXH53456.1 - 0.12 11.8 0.0 0.37 10.2 0.0 1.7 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus MCRA PF06100.11 KXH53456.1 - 0.23 10.2 0.0 0.34 9.7 0.0 1.2 1 0 0 1 1 1 0 MCRA family GST_N_2 PF13409.6 KXH53457.1 - 1.8e-20 73.0 0.0 3.4e-20 72.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KXH53457.1 - 6.9e-18 64.4 0.1 1.6e-17 63.3 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KXH53457.1 - 2.4e-09 37.3 0.0 4.5e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KXH53457.1 - 1.8e-05 25.1 0.0 0.1 13.0 0.0 2.5 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KXH53457.1 - 0.0012 19.1 0.0 0.0022 18.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 KXH53457.1 - 0.0054 16.5 0.0 0.01 15.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 KXH53457.1 - 0.028 14.6 0.0 0.28 11.4 0.0 2.3 2 0 0 2 2 2 0 Glutaredoxin Ribonuc_2-5A PF06479.12 KXH53705.1 - 3.6e-42 143.5 0.0 8e-42 142.4 0.0 1.6 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase PF00069.25 KXH53705.1 - 5.2e-41 140.8 0.0 1.5e-39 135.9 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXH53705.1 - 8.5e-21 74.4 0.0 2.4e-19 69.6 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KXH53705.1 - 0.00085 18.7 0.1 0.0023 17.3 0.1 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KXH53705.1 - 0.0027 16.6 0.5 0.0082 15.0 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 KXH53705.1 - 0.15 12.0 0.1 0.15 12.0 0.1 3.0 2 1 0 3 3 3 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 KXH53705.1 - 0.17 11.4 0.0 0.32 10.5 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL zf-C3HC4_3 PF13920.6 KXH53706.1 - 4.7e-06 26.4 8.8 4.7e-06 26.4 8.8 3.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXH53706.1 - 0.00058 19.6 12.3 0.00058 19.6 12.3 2.6 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Nbl1_Borealin_N PF10444.9 KXH53706.1 - 0.26 10.9 0.4 1.5 8.5 0.1 2.1 2 0 0 2 2 2 0 Nbl1 / Borealin N terminal SWIB PF02201.18 KXH53707.1 - 3.3e-31 107.0 0.8 5.6e-31 106.3 0.3 1.7 2 0 0 2 2 2 1 SWIB/MDM2 domain DEK_C PF08766.11 KXH53707.1 - 2.7e-16 59.2 0.7 1.7e-15 56.6 0.8 2.1 2 0 0 2 2 2 1 DEK C terminal domain FXMRP1_C_core PF12235.8 KXH53707.1 - 0.047 14.3 5.7 0.079 13.6 5.7 1.3 1 0 0 1 1 1 0 Fragile X-related 1 protein core C terminal SRP54_N PF02881.19 KXH53707.1 - 0.13 12.5 2.6 0.91 9.8 0.1 3.0 3 0 0 3 3 3 0 SRP54-type protein, helical bundle domain XRCC4 PF06632.12 KXH53707.1 - 0.22 10.3 10.3 0.35 9.7 10.0 1.5 1 1 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 adh_short PF00106.25 KXH53708.1 - 4.4e-21 75.2 0.0 1.1e-19 70.7 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXH53708.1 - 2.3e-12 47.0 0.0 3.6e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH53708.1 - 1.1e-05 25.4 0.0 2.3e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXH53708.1 - 0.00033 20.2 0.0 0.00093 18.7 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 KXH53708.1 - 0.011 15.0 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain RmlD_sub_bind PF04321.17 KXH53708.1 - 0.11 11.6 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain GH131_N PF18271.1 KXH53709.1 - 4.7e-64 216.5 1.1 5.8e-64 216.2 1.1 1.1 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain DUF3445 PF11927.8 KXH53710.1 - 2.3e-77 259.6 0.0 3.6e-77 259.0 0.0 1.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3445) Amidohydro_3 PF07969.11 KXH53711.1 - 2.8e-15 56.8 0.3 3.4e-10 40.0 0.0 3.2 3 0 0 3 3 3 2 Amidohydrolase family Amidohydro_1 PF01979.20 KXH53711.1 - 1.2e-11 44.6 0.0 1e-09 38.2 0.0 3.3 3 1 1 4 4 4 1 Amidohydrolase family LigB PF02900.18 KXH53712.1 - 7.4e-34 117.1 0.0 8.7e-34 116.8 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Glyco_hydro_61 PF03443.14 KXH53714.1 - 1.1e-49 169.2 0.6 1.8e-49 168.5 0.6 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 MGC-24 PF05283.11 KXH53714.1 - 6.9 7.1 10.5 17 5.9 10.5 1.6 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin CHCH PF06747.13 KXH53715.1 - 2.2e-06 27.7 2.7 3.4e-06 27.0 2.7 1.3 1 0 0 1 1 1 1 CHCH domain MTCP1 PF08991.10 KXH53715.1 - 0.0067 16.6 1.5 0.011 16.0 1.5 1.3 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type Pet191_N PF10203.9 KXH53715.1 - 0.041 14.2 2.8 0.14 12.5 2.8 1.8 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.10 KXH53715.1 - 0.21 11.6 3.5 3.9 7.6 0.2 2.4 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like NatB_MDM20 PF09797.9 KXH53716.1 - 8.7e-50 169.7 0.0 2e-49 168.5 0.0 1.6 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_14 PF13428.6 KXH53716.1 - 0.0037 17.9 0.4 22 6.2 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat Atg14 PF10186.9 KXH53716.1 - 0.25 10.4 4.6 0.14 11.2 1.9 1.9 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 zf-RanBP PF00641.18 KXH53716.1 - 1 8.7 7.7 3.5 7.0 7.7 1.9 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others Ilm1 PF10311.9 KXH53717.1 - 3e-51 173.3 2.0 5.7e-38 130.2 0.0 2.1 1 1 1 2 2 2 2 Increased loss of mitochondrial DNA protein 1 Prenyltrans PF00432.21 KXH53718.1 - 3.5e-31 106.6 9.4 2e-07 30.6 0.3 6.1 5 1 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat Pkinase PF00069.25 KXH53719.1 - 1.5e-64 217.9 0.0 2.1e-64 217.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXH53719.1 - 5.5e-40 137.3 0.0 7.6e-40 136.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXH53719.1 - 3e-09 36.6 0.0 6.5e-09 35.5 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 KXH53719.1 - 6.8e-05 22.0 0.2 6.8e-05 22.0 0.2 2.1 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 KXH53719.1 - 0.00061 19.8 6.0 0.02 14.8 0.1 3.5 2 2 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 KXH53719.1 - 0.027 13.8 0.1 0.058 12.7 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 KXH53719.1 - 0.09 11.8 0.0 0.13 11.3 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.22 KXH53719.1 - 2.5 7.7 4.8 0.34 10.5 0.1 1.9 2 0 0 2 2 2 0 RIO1 family M20_dimer PF07687.14 KXH53720.1 - 6.9e-19 67.8 0.1 1.2e-18 66.9 0.1 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 KXH53720.1 - 2.8e-18 66.4 0.5 5.1e-17 62.3 0.5 2.1 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.17 KXH53720.1 - 0.0079 15.9 0.0 0.012 15.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 IF-2B PF01008.17 KXH53721.1 - 2e-77 260.2 2.7 2.4e-77 259.9 2.7 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family TRAPPC10 PF12584.8 KXH53722.1 - 2.3e-24 85.9 0.0 6.2e-24 84.5 0.0 1.8 2 0 0 2 2 2 1 Trafficking protein particle complex subunit 10, TRAPPC10 HTH_3 PF01381.22 KXH53723.1 - 0.027 14.5 0.0 0.038 14.0 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix adh_short_C2 PF13561.6 KXH53724.1 - 2.5e-53 181.1 0.0 3.1e-53 180.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXH53724.1 - 1.6e-44 151.7 0.0 2e-44 151.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXH53724.1 - 9.8e-10 38.6 0.0 1.4e-09 38.1 0.0 1.1 1 0 0 1 1 1 1 KR domain PA PF02225.22 KXH53724.1 - 0.18 11.8 1.2 0.35 10.9 1.2 1.4 1 0 0 1 1 1 0 PA domain MFS_1 PF07690.16 KXH53725.1 - 2.8e-26 92.3 32.9 7.8e-16 57.9 15.1 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily Wzy_C PF04932.15 KXH53725.1 - 2.3 7.9 10.4 24 4.5 10.4 2.5 1 1 0 1 1 1 0 O-Antigen ligase Zn_clus PF00172.18 KXH53726.1 - 0.00077 19.5 2.7 0.0014 18.7 2.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.22 KXH53727.1 - 2.8e-33 115.4 0.1 5.1e-33 114.5 0.1 1.4 1 0 0 1 1 1 1 Cytochrome P450 Cys_Met_Meta_PP PF01053.20 KXH53728.1 - 1.2e-128 428.9 0.0 1.5e-128 428.6 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 KXH53728.1 - 1.2e-08 34.3 0.0 5.2e-08 32.2 0.0 2.0 1 1 1 2 2 2 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 KXH53728.1 - 8.2e-07 28.5 0.0 1.3e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II GDC-P PF02347.16 KXH53728.1 - 0.004 16.0 0.0 0.0059 15.5 0.0 1.2 1 0 0 1 1 1 1 Glycine cleavage system P-protein Met_gamma_lyase PF06838.11 KXH53728.1 - 0.007 14.9 0.0 0.01 14.4 0.0 1.3 1 0 0 1 1 1 1 Methionine gamma-lyase Glycos_transf_2 PF00535.26 KXH53728.1 - 0.014 15.3 0.3 0.67 9.7 0.2 2.4 2 0 0 2 2 2 0 Glycosyl transferase family 2 DegT_DnrJ_EryC1 PF01041.17 KXH53728.1 - 0.027 13.8 0.5 0.057 12.7 0.5 1.5 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family TNV_CP PF03898.13 KXH53728.1 - 0.19 11.0 2.0 0.16 11.2 0.5 1.6 2 0 0 2 2 2 0 Satellite tobacco necrosis virus coat protein adh_short PF00106.25 KXH53729.1 - 3e-31 108.4 0.1 1e-30 106.6 0.1 1.8 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXH53729.1 - 2.2e-20 73.2 0.0 3.8e-20 72.4 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KXH53729.1 - 5.8e-06 25.9 0.0 0.00033 20.2 0.1 2.8 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family PSD2 PF07624.11 KXH53729.1 - 0.015 15.1 0.0 0.052 13.3 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1585) KR PF08659.10 KXH53729.1 - 0.028 14.3 2.6 0.1 12.5 1.6 2.5 2 1 0 2 2 2 0 KR domain Eno-Rase_NADH_b PF12242.8 KXH53729.1 - 0.093 12.5 0.1 0.24 11.2 0.1 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 2OG-FeII_Oxy PF03171.20 KXH53730.1 - 4.1e-14 52.9 0.0 7.4e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 KXH53730.1 - 1.5e-09 38.6 0.0 2.4e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal UQ_con PF00179.26 KXH53852.1 - 3.3e-44 150.0 0.0 3.6e-29 101.2 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin-conjugating enzyme FDC-SP PF15215.6 KXH53852.1 - 0.044 14.3 0.4 0.32 11.5 0.0 2.2 2 0 0 2 2 2 0 Follicular dendritic cell secreted peptide TcpQ PF10671.9 KXH53852.1 - 0.058 13.5 0.1 0.15 12.2 0.1 1.7 1 0 0 1 1 1 0 Toxin co-regulated pilus biosynthesis protein Q CBM32 PF18344.1 KXH53852.1 - 0.059 13.2 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Carbohydrate binding module family 32 Rep_fac_C PF08542.11 KXH53853.1 - 1.9e-21 76.3 0.0 3.7e-21 75.3 0.0 1.5 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.29 KXH53853.1 - 6.3e-17 62.2 0.0 2.4e-16 60.4 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 KXH53853.1 - 7.5e-13 48.6 0.0 5.4e-12 45.8 0.0 2.1 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.15 KXH53853.1 - 2.6e-09 37.3 0.0 5.9e-09 36.1 0.0 1.7 1 1 0 1 1 1 1 Rad17 P-loop domain RuvB_N PF05496.12 KXH53853.1 - 6e-06 26.1 0.0 1.8e-05 24.5 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KXH53853.1 - 2.2e-05 24.9 0.0 0.00057 20.3 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain DNA_pol3_delta PF06144.13 KXH53853.1 - 3.9e-05 23.5 0.0 8.1e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_assoc_2 PF16193.5 KXH53853.1 - 5.2e-05 23.5 0.0 0.00015 22.1 0.0 1.8 1 0 0 1 1 1 1 AAA C-terminal domain AAA_11 PF13086.6 KXH53853.1 - 5.6e-05 23.1 0.1 0.00017 21.5 0.0 1.7 1 1 1 2 2 2 1 AAA domain AAA_22 PF13401.6 KXH53853.1 - 6.2e-05 23.3 0.0 0.0011 19.2 0.0 2.5 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 KXH53853.1 - 0.00031 20.2 0.0 0.014 14.8 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 KXH53853.1 - 0.00045 20.2 0.0 0.00096 19.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KXH53853.1 - 0.0028 18.0 0.0 0.022 15.1 0.0 2.2 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 KXH53853.1 - 0.0035 16.5 0.0 0.0056 15.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_30 PF13604.6 KXH53853.1 - 0.004 16.9 0.0 0.012 15.3 0.0 1.8 2 0 0 2 2 1 1 AAA domain DUF2075 PF09848.9 KXH53853.1 - 0.004 16.4 0.0 0.0084 15.4 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_24 PF13479.6 KXH53853.1 - 0.004 16.9 0.0 0.011 15.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KXH53853.1 - 0.0053 16.8 0.1 0.025 14.6 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 KXH53853.1 - 0.0065 16.7 0.0 0.013 15.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KXH53853.1 - 0.0067 16.0 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region ResIII PF04851.15 KXH53853.1 - 0.015 15.3 0.0 0.27 11.2 0.0 2.2 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit AAA_18 PF13238.6 KXH53853.1 - 0.026 15.1 0.0 0.066 13.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KXH53853.1 - 0.028 14.9 0.0 0.043 14.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KXH53853.1 - 0.035 14.5 0.0 0.081 13.3 0.0 1.7 1 1 0 1 1 1 0 RNA helicase AAA_3 PF07726.11 KXH53853.1 - 0.048 13.5 0.0 0.28 11.0 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DEAD PF00270.29 KXH53853.1 - 0.051 13.3 0.6 1.3 8.8 0.0 2.8 2 1 0 3 3 3 0 DEAD/DEAH box helicase PhoH PF02562.16 KXH53853.1 - 0.072 12.5 0.1 2.3 7.6 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein AAA_33 PF13671.6 KXH53853.1 - 0.13 12.4 0.0 0.27 11.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain Apo-CII PF05355.11 KXH53854.1 - 0.0033 17.5 0.0 3.5 7.9 0.0 2.9 3 0 0 3 3 3 2 Apolipoprotein C-II 3H PF02829.14 KXH53854.1 - 0.077 13.3 1.9 14 6.0 0.4 2.8 2 0 0 2 2 2 0 3H domain Exonuc_VII_S PF02609.16 KXH53854.1 - 0.09 12.9 0.3 0.33 11.0 0.3 2.1 1 0 0 1 1 1 0 Exonuclease VII small subunit Sec63 PF02889.16 KXH53855.1 - 4.2e-165 547.1 0.3 2.2e-92 308.8 0.0 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 KXH53855.1 - 5.8e-49 166.2 0.1 1.6e-28 99.6 0.0 3.3 4 0 0 4 4 4 2 DEAD/DEAH box helicase Helicase_PWI PF18149.1 KXH53855.1 - 3.4e-34 117.4 1.8 9.6e-34 115.9 1.8 1.8 1 0 0 1 1 1 1 N-terminal helicase PWI domain ResIII PF04851.15 KXH53855.1 - 6.1e-24 84.9 0.0 1.5e-13 51.1 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KXH53855.1 - 2.4e-10 40.8 0.0 2.5e-07 31.0 0.0 3.7 2 2 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 KXH53855.1 - 7.3e-06 26.3 0.4 0.018 15.3 0.0 3.6 2 2 0 2 2 2 2 AAA domain T2SSE PF00437.20 KXH53855.1 - 0.0046 16.0 0.0 2 7.4 0.0 2.5 2 0 0 2 2 2 2 Type II/IV secretion system protein PhoH PF02562.16 KXH53855.1 - 0.068 12.6 0.0 3.1 7.2 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein UvrD-helicase PF00580.21 KXH53855.1 - 0.1 12.1 1.1 3.5 7.1 0.0 2.9 3 0 0 3 3 3 0 UvrD/REP helicase N-terminal domain AAA_19 PF13245.6 KXH53855.1 - 0.14 12.5 0.0 26 5.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain BUD22 PF09073.10 KXH53855.1 - 0.26 10.6 14.9 0.5 9.6 14.9 1.4 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 KXH53855.1 - 7.7 5.8 22.8 18 4.6 22.8 1.6 1 0 0 1 1 1 0 SDA1 PWWP PF00855.17 KXH53856.1 - 8.9e-16 58.1 0.0 8.9e-16 58.1 0.0 4.4 3 1 2 5 5 5 1 PWWP domain Med26 PF08711.11 KXH53856.1 - 0.00055 19.9 0.3 0.0015 18.5 0.3 1.8 1 0 0 1 1 1 1 TFIIS helical bundle-like domain ORC3_N PF07034.11 KXH53857.1 - 1.3e-37 129.7 5.5 2.4e-35 122.2 5.5 2.2 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus ORC_WH_C PF18137.1 KXH53857.1 - 2.5e-25 89.2 0.3 2.6e-15 56.7 0.0 2.6 1 1 1 2 2 2 2 Origin recognition complex winged helix C-terminal Pox_I6 PF04595.13 KXH53857.1 - 0.047 12.6 0.0 0.1 11.5 0.0 1.5 1 0 0 1 1 1 0 Poxvirus I6-like family ApoC-I PF04691.12 KXH53857.1 - 0.22 11.5 1.5 11 6.1 0.1 3.0 3 0 0 3 3 3 0 Apolipoprotein C-I (ApoC-1) Sec66 PF09802.9 KXH53859.1 - 4.8e-81 270.6 0.7 5.7e-81 270.4 0.7 1.1 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 DUF3848 PF12959.7 KXH53859.1 - 0.028 14.5 0.2 0.081 13.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3848) PEP-utilisers_N PF05524.13 KXH53859.1 - 0.17 12.1 1.7 0.25 11.5 1.4 1.4 1 1 0 1 1 1 0 PEP-utilising enzyme, N-terminal PaREP1 PF05942.11 KXH53859.1 - 1.4 8.8 4.2 1.8 8.5 0.7 2.1 1 1 1 2 2 2 0 Archaeal PaREP1/PaREP8 family NPL4 PF05021.15 KXH53860.1 - 8.8e-137 455.5 0.0 1.2e-136 455.1 0.0 1.2 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.15 KXH53860.1 - 1.6e-69 232.6 0.1 2.6e-69 231.9 0.1 1.3 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.8 KXH53860.1 - 0.0033 17.9 0.0 0.024 15.1 0.0 2.2 1 1 0 1 1 1 1 Nuclear pore localisation protein NPL4 CPSase_L_D2 PF02786.17 KXH53861.1 - 9.6e-108 358.5 0.0 1.2e-83 279.7 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 KXH53861.1 - 5.4e-40 136.5 0.1 1.6e-39 135.0 0.1 1.9 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp PF02222.22 KXH53861.1 - 2.3e-21 76.1 0.0 1.1e-10 41.3 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.13 KXH53861.1 - 7.3e-19 68.1 0.3 4.1e-08 33.0 0.0 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 KXH53861.1 - 8.8e-11 41.7 0.0 0.00063 19.5 0.0 2.8 3 0 0 3 3 3 2 ATP-grasp in the biosynthetic pathway with Ter operon GARS_A PF01071.19 KXH53861.1 - 1.1e-05 25.4 2.3 0.0067 16.2 0.1 2.8 3 0 0 3 3 3 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_3 PF02655.14 KXH53861.1 - 1.1e-05 25.6 0.4 0.23 11.5 0.0 3.2 3 0 0 3 3 3 2 ATP-grasp domain ATP-grasp_5 PF13549.6 KXH53861.1 - 1.7e-05 24.4 0.0 0.25 10.8 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp domain RimK PF08443.11 KXH53861.1 - 1.7e-05 24.5 0.0 0.021 14.5 0.0 2.6 2 0 0 2 2 2 2 RimK-like ATP-grasp domain ATP-grasp_4 PF13535.6 KXH53861.1 - 0.00063 19.4 0.0 0.0083 15.7 0.0 2.6 2 0 0 2 2 2 1 ATP-grasp domain tRNA-synt_2d PF01409.20 KXH53862.1 - 6.9e-86 287.7 0.0 9.8e-86 287.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD3 PF18553.1 KXH53862.1 - 2e-17 63.2 0.9 4.4e-17 62.1 0.9 1.7 1 0 0 1 1 1 1 PheRS DNA binding domain 3 tRNA_synthFbeta PF17759.1 KXH53862.1 - 6.7e-07 29.0 0.0 0.0031 17.0 0.0 3.1 3 0 0 3 3 3 2 Phenylalanyl tRNA synthetase beta chain CLM domain PheRS_DBD2 PF18554.1 KXH53862.1 - 8.7e-06 25.6 1.9 2.4e-05 24.2 1.9 1.9 1 0 0 1 1 1 1 PheRS DNA binding domain 2 tRNA-synt_2 PF00152.20 KXH53862.1 - 3.4e-05 23.1 0.9 0.0015 17.6 0.0 3.1 4 0 0 4 4 4 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.25 KXH53862.1 - 0.021 14.8 0.0 0.037 14.0 0.0 1.5 1 0 0 1 1 1 0 tRNA synthetase class II core domain (G, H, P, S and T) ESP PF16590.5 KXH53862.1 - 1.1 9.6 3.8 4.9 7.5 0.3 2.6 3 0 0 3 3 3 0 Exocrine gland-secreting peptide DUF1746 PF08508.10 KXH53863.1 - 2e-40 137.7 0.3 2.6e-40 137.3 0.3 1.1 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1746) REV PF00424.18 KXH53863.1 - 0.16 12.0 3.5 0.75 9.9 0.5 2.3 2 0 0 2 2 2 0 REV protein (anti-repression trans-activator protein) RTC_insert PF05189.13 KXH53864.1 - 7.7e-30 103.5 0.1 1.4e-29 102.6 0.1 1.4 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain RTC PF01137.21 KXH53864.1 - 3.7e-28 98.2 0.2 4.6e-28 97.9 0.2 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase PPR_2 PF13041.6 KXH53865.1 - 9.4e-10 38.5 0.0 0.00011 22.4 0.0 4.4 4 0 0 4 4 4 2 PPR repeat family PPR PF01535.20 KXH53865.1 - 0.00011 22.2 0.2 1.8 9.0 0.0 4.7 4 0 0 4 4 4 2 PPR repeat PPR_3 PF13812.6 KXH53865.1 - 0.024 14.7 0.0 3.1 7.9 0.0 3.0 3 0 0 3 3 3 0 Pentatricopeptide repeat domain KIX_2 PF16987.5 KXH53865.1 - 0.069 13.1 0.0 0.29 11.1 0.0 2.1 1 0 0 1 1 1 0 KIX domain ECM11 PF15463.6 KXH53865.1 - 2.1 9.0 5.7 10 6.7 0.1 3.4 4 0 0 4 4 4 0 Extracellular mutant protein 11 DUF4187 PF13821.6 KXH53866.1 - 7.9e-23 80.0 4.3 2.5e-22 78.4 4.3 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.23 KXH53866.1 - 1.1e-09 38.1 3.2 2.3e-09 37.0 3.2 1.6 1 0 0 1 1 1 1 G-patch domain DUF4301 PF14134.6 KXH53866.1 - 0.037 12.8 0.0 0.058 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4301) G-patch_2 PF12656.7 KXH53866.1 - 0.26 11.4 6.4 0.11 12.5 2.4 2.6 2 0 0 2 2 2 0 G-patch domain Nop14 PF04147.12 KXH53867.1 - 3.7e-296 985.0 33.5 4.8e-296 984.6 33.5 1.1 1 0 0 1 1 1 1 Nop14-like family CAP_GLY PF01302.25 KXH53869.1 - 1.6e-15 56.9 0.1 3.4e-15 55.8 0.1 1.6 1 0 0 1 1 1 1 CAP-Gly domain CLIP1_ZNF PF16641.5 KXH53869.1 - 2.4e-07 30.4 11.0 0.0012 18.6 1.1 2.4 2 0 0 2 2 2 2 CLIP1 zinc knuckle AAA_13 PF13166.6 KXH53869.1 - 0.001 17.8 5.0 0.001 17.8 5.0 2.0 1 1 1 2 2 2 1 AAA domain DUF3584 PF12128.8 KXH53869.1 - 0.0039 14.8 22.5 0.0054 14.3 22.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) TMF_DNA_bd PF12329.8 KXH53869.1 - 0.016 15.2 29.2 0.29 11.1 2.2 5.3 5 0 0 5 5 5 0 TATA element modulatory factor 1 DNA binding NPV_P10 PF05531.12 KXH53869.1 - 0.036 14.5 5.4 2.9 8.4 0.1 3.1 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF305 PF03713.13 KXH53869.1 - 0.59 10.3 7.4 0.12 12.5 2.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF305) BLOC1_2 PF10046.9 KXH53869.1 - 0.61 10.4 12.1 0.11 12.9 2.1 3.2 4 0 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 zf_PR_Knuckle PF18445.1 KXH53869.1 - 0.79 9.6 2.8 4.7 7.1 0.1 2.4 2 0 0 2 2 2 0 PR zinc knuckle motif DUF948 PF06103.11 KXH53869.1 - 0.81 10.0 2.8 1.4 9.3 0.3 2.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Spc7 PF08317.11 KXH53869.1 - 1.7 7.5 28.8 0.51 9.2 11.6 3.2 2 1 1 3 3 3 0 Spc7 kinetochore protein Fez1 PF06818.15 KXH53869.1 - 1.7 9.0 31.6 0.52 10.7 12.6 3.2 2 1 1 3 3 3 0 Fez1 Glutaredoxin2_C PF04399.13 KXH53869.1 - 1.9 8.3 3.9 5.4 6.9 0.6 2.4 2 0 0 2 2 2 0 Glutaredoxin 2, C terminal domain KIP1 PF07765.12 KXH53869.1 - 2.9 8.1 6.5 0.97 9.6 2.4 2.3 2 0 0 2 2 2 0 KIP1-like protein DUF812 PF05667.11 KXH53869.1 - 3 6.6 28.3 0.11 11.3 16.8 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF812) HrpB7 PF09486.10 KXH53869.1 - 3 8.2 28.2 3.1 8.2 0.6 3.6 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB7) DUF4407 PF14362.6 KXH53869.1 - 5 6.4 23.9 1.1e+02 2.0 0.5 3.0 1 1 1 2 2 1 0 Domain of unknown function (DUF4407) Fib_alpha PF08702.10 KXH53869.1 - 5.8 7.1 14.4 7.1 6.8 4.5 3.3 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family EMP24_GP25L PF01105.24 KXH53869.1 - 7 6.5 7.4 3.8 7.4 1.1 2.6 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Pkinase PF00069.25 KXH53870.1 - 1.4e-32 113.1 0.0 1.2e-19 70.7 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXH53870.1 - 2e-11 43.7 0.0 0.0011 18.4 0.0 3.1 3 0 0 3 3 3 3 Protein tyrosine kinase APH PF01636.23 KXH53870.1 - 0.0028 17.6 0.1 0.04 13.8 0.1 2.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KXH53870.1 - 0.0047 16.3 0.0 0.43 9.8 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Glyco_hydro_38N PF01074.22 KXH53871.1 - 4.4e-88 295.4 1.5 6.8e-88 294.8 1.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 KXH53871.1 - 1.2e-57 195.4 0.3 1.1e-56 192.3 0.2 2.2 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 KXH53871.1 - 2.8e-27 94.7 0.0 6.4e-27 93.5 0.0 1.7 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 KXH53871.1 - 3e-12 46.5 0.0 1.7e-11 44.0 0.0 2.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain TubC_N PF18563.1 KXH53871.1 - 0.11 12.5 0.0 9.4 6.3 0.0 2.5 2 0 0 2 2 2 0 TubC N-terminal docking domain TFIIA PF03153.13 KXH53872.1 - 2.5e-05 24.5 6.5 4.6e-05 23.6 6.5 1.4 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Thioredoxin_12 PF18400.1 KXH53872.1 - 0.24 11.2 1.1 0.44 10.4 1.1 1.4 1 0 0 1 1 1 0 Thioredoxin-like domain MutS_V PF00488.21 KXH53873.1 - 1.6e-69 233.7 0.0 3.4e-69 232.7 0.0 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KXH53873.1 - 2.1e-46 158.5 5.8 3.7e-46 157.8 5.8 1.4 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 KXH53873.1 - 7.1e-19 68.1 0.0 1.8e-18 66.8 0.0 1.7 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 KXH53873.1 - 1.5e-07 31.8 0.0 3.5e-07 30.6 0.0 1.7 1 0 0 1 1 1 1 MutS domain II AAA_29 PF13555.6 KXH53873.1 - 0.097 12.4 0.8 0.33 10.7 0.1 2.1 1 1 1 2 2 2 0 P-loop containing region of AAA domain AAA_27 PF13514.6 KXH53873.1 - 0.11 12.1 0.1 0.29 10.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 KXH53873.1 - 0.21 12.1 0.0 0.39 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Ribosomal_L10 PF00466.20 KXH53874.1 - 1.2e-22 80.0 0.1 3.6e-22 78.4 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein L10 RL10P_insert PF17777.1 KXH53874.1 - 1.5e-21 76.1 0.0 3.3e-21 75.1 0.0 1.6 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_60s PF00428.19 KXH53874.1 - 6.6e-18 65.1 6.6 7.2e-18 65.0 3.7 2.2 2 0 0 2 2 2 1 60s Acidic ribosomal protein WRNPLPNID PF15017.6 KXH53874.1 - 0.093 13.6 0.8 0.17 12.8 0.8 1.4 1 0 0 1 1 1 0 Putative WW-binding domain and destruction box CPSF_A PF03178.15 KXH53875.1 - 2.5e-05 23.8 0.0 0.00055 19.4 0.0 2.2 1 1 1 2 2 2 1 CPSF A subunit region PQQ_2 PF13360.6 KXH53875.1 - 0.011 15.3 0.1 0.17 11.5 0.0 2.5 2 0 0 2 2 2 0 PQQ-like domain WD40 PF00400.32 KXH53875.1 - 0.023 15.6 0.7 6.9 7.7 0.1 3.7 3 0 0 3 3 3 0 WD domain, G-beta repeat VRP3 PF03536.15 KXH53875.1 - 0.055 13.0 0.1 0.15 11.6 0.0 1.7 2 0 0 2 2 2 0 Salmonella virulence-associated 28kDa protein DUF2694 PF10904.8 KXH53875.1 - 0.056 13.5 0.1 0.26 11.4 0.1 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2694) Lgl_C PF08596.10 KXH53875.1 - 0.1 11.2 0.1 0.17 10.5 0.1 1.3 1 0 0 1 1 1 0 Lethal giant larvae(Lgl) like, C-terminal Cytomega_UL20A PF05984.12 KXH53875.1 - 0.64 10.4 6.1 5.8 7.3 0.0 3.3 4 0 0 4 4 4 0 Cytomegalovirus UL20A protein DnaJ_C PF01556.18 KXH53876.1 - 5.8e-38 130.3 0.1 8.1e-38 129.8 0.1 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KXH53876.1 - 5.3e-26 90.5 3.1 9.1e-26 89.8 3.1 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KXH53876.1 - 8.5e-16 58.1 20.1 1.5e-15 57.3 20.1 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.19 KXH53876.1 - 0.25 11.4 11.0 0.63 10.1 2.6 2.5 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 KXH53876.1 - 0.95 9.5 6.5 5 7.2 0.9 2.3 2 0 0 2 2 2 0 Double zinc ribbon Anti-TRAP PF15777.5 KXH53876.1 - 1.6 8.8 17.3 0.87 9.6 3.1 2.6 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein zinc-ribbons_6 PF07191.12 KXH53876.1 - 3.3 7.8 8.4 3.3 7.8 2.3 2.3 2 0 0 2 2 2 0 zinc-ribbons adh_short_C2 PF13561.6 KXH53877.1 - 7.7e-33 114.0 0.0 1e-20 74.3 0.0 3.1 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXH53877.1 - 9.9e-26 90.4 0.0 1.8e-25 89.6 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase dCMP_cyt_deam_1 PF00383.23 KXH53877.1 - 1.5e-13 50.5 0.3 3.6e-13 49.2 0.3 1.6 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 KXH53877.1 - 7.7e-08 32.6 1.6 3.4e-07 30.5 0.1 2.3 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region KR PF08659.10 KXH53877.1 - 2.2e-07 31.0 0.0 1.2e-06 28.5 0.0 2.0 2 0 0 2 2 2 1 KR domain XOO_2897-deam PF14440.6 KXH53877.1 - 0.019 15.1 0.1 0.79 9.9 0.0 2.3 2 0 0 2 2 2 0 Xanthomonas XOO_2897-like deaminase LmjF365940-deam PF14421.6 KXH53877.1 - 0.068 12.8 1.6 3.6 7.1 0.0 2.3 1 1 1 2 2 2 0 A distinct subfamily of CDD/CDA-like deaminases DEAD PF00270.29 KXH53878.1 - 5.7e-46 156.5 1.3 9.2e-46 155.8 1.3 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXH53878.1 - 6e-32 110.3 0.4 8.7e-31 106.5 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXH53878.1 - 2.6e-06 27.5 0.0 4.3e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 KXH53878.1 - 0.00018 21.3 0.1 0.00037 20.3 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KXH53878.1 - 0.00031 21.1 1.8 0.0012 19.2 0.7 2.2 2 1 0 2 2 2 1 AAA domain CMS1 PF14617.6 KXH53878.1 - 0.024 14.0 0.0 0.051 12.9 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit AAA_22 PF13401.6 KXH53878.1 - 0.031 14.5 0.9 0.19 12.0 0.9 2.2 1 1 0 1 1 1 0 AAA domain Helicase_RecD PF05127.14 KXH53878.1 - 0.058 13.3 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 Helicase UvrD-helicase PF00580.21 KXH53878.1 - 0.07 12.6 0.4 0.1 12.1 0.3 1.4 1 1 0 1 1 1 0 UvrD/REP helicase N-terminal domain Flavi_DEAD PF07652.14 KXH53878.1 - 0.079 12.9 0.2 0.38 10.7 0.2 2.2 1 1 0 1 1 1 0 Flavivirus DEAD domain IL17R_D_N PF16742.5 KXH53878.1 - 0.084 12.9 0.0 0.23 11.5 0.0 1.7 1 0 0 1 1 1 0 N-terminus of interleukin 17 receptor D fragilysinNterm PF16376.5 KXH53878.1 - 0.092 12.5 0.0 0.27 11.0 0.0 1.7 1 0 0 1 1 1 0 N-terminal domain of fragilysin tRNA-synt_1b PF00579.25 KXH53878.1 - 0.093 12.0 0.2 0.47 9.7 0.0 2.1 3 0 0 3 3 3 0 tRNA synthetases class I (W and Y) Cupin_8 PF13621.6 KXH53879.1 - 1.4e-15 57.8 0.1 3.9e-14 53.0 0.1 2.2 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 KXH53879.1 - 2.5e-09 37.6 0.3 1.5e-08 35.0 0.1 2.4 2 1 0 2 2 2 1 JmjC domain, hydroxylase F-box-like PF12937.7 KXH53879.1 - 9.1e-06 25.5 0.4 2.4e-05 24.1 0.3 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KXH53879.1 - 0.00041 20.2 0.2 0.0011 18.7 0.2 1.8 1 0 0 1 1 1 1 F-box domain DUF1771 PF08590.10 KXH53881.1 - 2.5e-15 56.6 11.6 8.5e-15 54.9 11.6 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) zf_CCCH_4 PF18345.1 KXH53881.1 - 3.4e-08 33.3 7.9 1e-05 25.4 0.4 2.9 2 1 0 2 2 2 2 Zinc finger domain Smr PF01713.21 KXH53881.1 - 8.4e-07 29.3 0.0 2.6e-06 27.7 0.0 1.8 1 0 0 1 1 1 1 Smr domain zf-CCCH PF00642.24 KXH53881.1 - 3e-06 27.0 3.4 0.0011 18.8 0.4 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 KXH53881.1 - 0.00025 21.4 4.5 0.11 13.0 0.8 2.4 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger zf-CCCH_4 PF18044.1 KXH53881.1 - 0.00037 20.2 11.1 0.0056 16.4 0.3 3.1 2 1 0 2 2 2 1 CCCH-type zinc finger HBS1_N PF08938.10 KXH53881.1 - 0.0053 17.0 0.0 0.014 15.7 0.0 1.6 1 0 0 1 1 1 1 HBS1 N-terminus zf-CCCH_3 PF15663.5 KXH53881.1 - 0.21 11.8 2.8 9.1 6.5 0.1 2.3 1 1 1 2 2 2 0 Zinc-finger containing family Torus PF16131.5 KXH53881.1 - 0.76 10.5 5.4 1.6 9.4 0.5 2.4 1 1 1 2 2 2 0 Torus domain SNARE_assoc PF09335.11 KXH53882.1 - 3.8e-12 46.8 9.2 3.8e-12 46.8 9.2 2.4 2 0 0 2 2 2 1 SNARE associated Golgi protein GRP PF07172.11 KXH53882.1 - 0.016 15.9 1.4 0.016 15.9 1.4 1.9 2 0 0 2 2 2 0 Glycine rich protein family ZapB PF06005.12 KXH53883.1 - 0.88 10.1 4.4 22 5.5 0.0 2.4 2 0 0 2 2 2 0 Cell division protein ZapB Abhydrolase_1 PF00561.20 KXH53884.1 - 3.6e-13 49.7 0.0 1e-12 48.2 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXH53884.1 - 2.4e-09 36.8 0.0 4.5e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KXH53884.1 - 0.00061 20.5 0.0 0.0039 17.8 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S28 PF05577.12 KXH53884.1 - 0.0025 16.7 0.0 0.0058 15.5 0.0 1.6 2 0 0 2 2 2 1 Serine carboxypeptidase S28 Esterase PF00756.20 KXH53884.1 - 0.0038 16.9 0.0 0.0069 16.1 0.0 1.5 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 KXH53884.1 - 0.0059 16.1 0.0 0.022 14.2 0.0 1.9 1 1 0 1 1 1 1 Prolyl oligopeptidase family LIDHydrolase PF10230.9 KXH53884.1 - 0.073 12.6 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase COesterase PF00135.28 KXH53885.1 - 7.1e-59 200.0 0.0 2e-58 198.5 0.0 1.7 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXH53885.1 - 1.4e-05 25.1 0.1 0.00011 22.1 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KXH53885.1 - 5.7e-05 22.7 0.0 9.4e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family BTB PF00651.31 KXH53886.1 - 7.8e-06 26.1 0.1 2.1e-05 24.7 0.0 1.7 2 0 0 2 2 2 1 BTB/POZ domain HHH_5 PF14520.6 KXH53887.1 - 0.0013 19.3 0.0 0.01 16.4 0.0 2.4 2 0 0 2 2 2 1 Helix-hairpin-helix domain MtlR PF05068.12 KXH53887.1 - 0.035 14.1 0.0 0.079 13.0 0.0 1.6 1 0 0 1 1 1 0 Mannitol repressor DNA_pol_lambd_f PF10391.9 KXH53887.1 - 0.074 12.9 0.0 1.1 9.2 0.0 2.4 2 0 0 2 2 2 0 Fingers domain of DNA polymerase lambda DEAD PF00270.29 KXH53888.1 - 7e-11 42.2 0.0 1.3e-10 41.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KXH53888.1 - 0.076 13.0 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit MFS_1 PF07690.16 KXH53976.1 - 2.7e-32 112.1 54.0 1.9e-31 109.3 47.6 3.1 2 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KXH53976.1 - 3.7e-12 45.5 12.8 3.7e-12 45.5 12.8 1.9 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Transferase PF02458.15 KXH53977.1 - 8.8e-08 31.2 0.5 4.1e-07 29.0 0.1 2.1 2 1 0 2 2 2 1 Transferase family Leucyl-specific PF14795.6 KXH53977.1 - 0.019 15.0 0.1 0.048 13.7 0.1 1.7 1 0 0 1 1 1 0 Leucine-tRNA synthetase-specific domain GFO_IDH_MocA PF01408.22 KXH53978.1 - 8.7e-19 68.5 0.0 2.1e-18 67.3 0.0 1.6 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold tRNA-synt_1f PF01921.18 KXH53978.1 - 0.026 13.4 0.1 0.045 12.7 0.1 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (K) Semialdhyde_dh PF01118.24 KXH53978.1 - 0.17 12.3 0.0 0.36 11.3 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Ank_2 PF12796.7 KXH53979.1 - 2e-11 44.3 0.0 0.00084 19.9 0.0 3.6 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXH53979.1 - 3.8e-11 43.0 0.1 0.0011 19.2 0.0 3.8 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXH53979.1 - 8.8e-10 38.0 0.1 0.0029 18.0 0.0 5.3 5 0 0 5 5 5 2 Ankyrin repeat Ank PF00023.30 KXH53979.1 - 1.6e-09 37.8 2.0 0.00017 21.9 0.0 4.9 6 0 0 6 6 6 2 Ankyrin repeat Ank_4 PF13637.6 KXH53979.1 - 1.4e-07 31.9 0.1 0.34 11.6 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeats (many copies) GFA PF04828.14 KXH53989.1 - 2.3e-12 47.1 0.0 9.5e-07 29.1 0.3 2.3 2 0 0 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme Glutaredoxin PF00462.24 KXH53991.1 - 9.4e-14 51.4 0.0 3.3e-13 49.6 0.0 2.0 1 0 0 1 1 1 1 Glutaredoxin Herpes_UL25 PF01499.16 KXH53991.1 - 0.17 10.3 1.5 0.36 9.3 1.5 1.4 1 0 0 1 1 1 0 Herpesvirus UL25 family PPL5 PF18168.1 KXH53991.1 - 0.36 10.1 4.2 0.55 9.5 4.2 1.2 1 0 0 1 1 1 0 Prim-pol family 5 SAPS PF04499.15 KXH53991.1 - 3 6.5 9.3 5.4 5.7 6.3 2.0 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein F-box PF00646.33 KXH53992.1 - 0.028 14.3 0.0 0.054 13.4 0.0 1.4 1 0 0 1 1 1 0 F-box domain z-alpha PF02295.17 KXH53993.1 - 0.055 13.5 0.0 0.27 11.3 0.0 1.8 1 1 1 2 2 2 0 Adenosine deaminase z-alpha domain ADH_zinc_N PF00107.26 KXH53994.1 - 2.3e-11 43.8 0.6 3.9e-11 43.0 0.2 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXH53994.1 - 5.1e-05 24.3 0.0 0.00016 22.7 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXH53994.1 - 0.0021 17.9 0.0 0.0041 17.0 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Brix PF04427.18 KXH53995.1 - 4.7e-37 128.0 0.0 6.1e-37 127.6 0.0 1.1 1 0 0 1 1 1 1 Brix domain Rrn6 PF10214.9 KXH53996.1 - 0.37 9.2 3.4 0.44 9.0 3.4 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor U79_P34 PF03064.16 KXH53996.1 - 0.67 9.3 5.5 0.8 9.0 5.5 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Ndc1_Nup PF09531.10 KXH53996.1 - 2.2 6.9 3.6 2.5 6.7 3.6 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup BNR_2 PF13088.6 KXH53997.1 - 1e-20 74.2 0.3 2.8e-09 36.7 0.0 2.8 1 1 2 3 3 3 3 BNR repeat-like domain BNR PF02012.20 KXH53997.1 - 3.2e-08 32.4 17.8 0.023 14.6 0.4 5.6 5 0 0 5 5 5 4 BNR/Asp-box repeat CHB_HEX_C PF03174.13 KXH53997.1 - 0.033 14.2 0.2 8.2 6.5 0.0 4.0 5 0 0 5 5 5 0 Chitobiase/beta-hexosaminidase C-terminal domain Sortilin-Vps10 PF15902.5 KXH53997.1 - 0.1 11.4 5.4 0.91 8.2 0.5 3.4 2 2 1 3 3 3 0 Sortilin, neurotensin receptor 3, Mo-co_dimer PF03404.16 KXH53997.1 - 0.85 9.6 4.4 2.9 7.9 0.1 3.0 4 0 0 4 4 4 0 Mo-co oxidoreductase dimerisation domain SGL PF08450.12 KXH53999.1 - 0.0086 15.7 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Dicty_CTDC PF00526.18 KXH53999.1 - 0.3 11.0 0.9 0.57 10.1 0.9 1.5 1 0 0 1 1 1 0 Dictyostelium (slime mold) repeat Tim17 PF02466.19 KXH54000.1 - 2.1e-15 57.1 0.0 3.5e-15 56.3 0.0 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Oxidored_FMN PF00724.20 KXH54002.1 - 8.3e-83 278.5 0.0 1.1e-82 278.1 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Ribosomal_S19 PF00203.21 KXH54003.1 - 4.8e-32 109.7 0.2 6.6e-32 109.2 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 EpmC PF04315.12 KXH54003.1 - 0.14 11.9 0.0 3.8 7.2 0.0 2.1 2 0 0 2 2 2 0 Elongation factor P hydroxylase SIL1 PF16782.5 KXH54004.1 - 2.1e-09 37.0 0.0 3.8e-09 36.2 0.0 1.4 1 1 0 1 1 1 1 Nucleotide exchange factor SIL1 SUI1 PF01253.22 KXH54007.1 - 2.8e-27 95.0 2.1 2.8e-27 95.0 2.1 1.5 2 0 0 2 2 2 1 Translation initiation factor SUI1 zf-MYND PF01753.18 KXH54008.1 - 7.5e-10 38.7 11.1 1.6e-09 37.7 11.1 1.6 1 0 0 1 1 1 1 MYND finger SET PF00856.28 KXH54008.1 - 4.8e-08 33.6 0.0 2e-07 31.6 0.0 2.1 2 1 0 2 2 2 1 SET domain Trimer_CC PF08954.11 KXH54009.1 - 0.00011 21.7 4.2 0.0028 17.2 0.0 3.2 3 0 0 3 3 3 1 Trimerisation motif TMF_TATA_bd PF12325.8 KXH54009.1 - 0.0037 17.5 18.0 0.006 16.8 3.6 3.2 1 1 1 3 3 3 2 TATA element modulatory factor 1 TATA binding FAM72 PF14976.6 KXH54009.1 - 0.0078 16.4 0.2 0.02 15.0 0.2 1.7 1 0 0 1 1 1 1 FAM72 protein DUF4515 PF14988.6 KXH54009.1 - 0.012 15.4 4.6 0.012 15.4 4.6 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4515) Yippee-Mis18 PF03226.14 KXH54009.1 - 0.049 13.9 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly AAA_13 PF13166.6 KXH54009.1 - 0.052 12.2 15.8 0.0072 15.0 11.8 1.5 2 0 0 2 2 2 0 AAA domain LPP PF04728.13 KXH54009.1 - 0.12 12.8 8.6 0.92 10.0 0.3 4.1 4 0 0 4 4 4 0 Lipoprotein leucine-zipper DUF1848 PF08902.11 KXH54009.1 - 0.12 12.1 1.7 0.27 10.9 1.6 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF1848) Hemagglutinin PF00509.18 KXH54009.1 - 0.12 10.7 3.6 0.051 12.0 0.1 1.9 1 1 1 2 2 2 0 Haemagglutinin USP19_linker PF16602.5 KXH54009.1 - 0.17 12.4 3.2 0.27 11.8 1.0 2.3 1 1 1 2 2 2 0 Linker region of USP19 deubiquitinase RPW8 PF05659.11 KXH54009.1 - 0.27 10.9 11.3 8 6.1 3.0 3.5 1 1 2 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Spectrin PF00435.21 KXH54009.1 - 0.34 11.4 10.8 0.45 11.0 0.1 3.3 2 1 1 3 3 3 0 Spectrin repeat DUF4200 PF13863.6 KXH54009.1 - 0.45 10.9 15.0 25 5.3 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4200) YabA PF06156.13 KXH54009.1 - 0.51 11.0 20.1 1.6 9.4 3.6 4.2 1 1 3 4 4 4 0 Initiation control protein YabA Cnn_1N PF07989.11 KXH54009.1 - 0.82 9.9 15.0 14 5.9 8.6 4.1 3 1 1 4 4 4 0 Centrosomin N-terminal motif 1 FlaC_arch PF05377.11 KXH54009.1 - 0.89 10.0 11.6 3.9 7.9 0.3 4.4 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) Fib_alpha PF08702.10 KXH54009.1 - 0.93 9.7 21.1 1.7 8.8 0.3 3.3 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.12 KXH54009.1 - 1.1 9.4 14.2 0.35 10.9 1.0 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DUF4407 PF14362.6 KXH54009.1 - 1.1 8.6 11.3 11 5.2 11.3 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DASH_Dad4 PF08650.10 KXH54009.1 - 1.2 9.1 7.7 7.3 6.6 1.0 3.1 3 0 0 3 3 3 0 DASH complex subunit Dad4 APC_N_CC PF16689.5 KXH54009.1 - 1.2 9.2 14.3 1.1 9.4 2.1 4.4 4 1 1 5 5 4 0 Coiled-coil N-terminus of APC, dimerisation domain BLOC1_2 PF10046.9 KXH54009.1 - 1.4 9.3 15.9 16 5.9 4.1 4.2 2 1 2 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4472 PF14739.6 KXH54009.1 - 1.8 9.3 15.8 0.69 10.7 7.2 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4472) zf-C4H2 PF10146.9 KXH54009.1 - 2.1 8.6 18.7 1.9 8.7 14.5 2.1 1 1 1 2 2 2 0 Zinc finger-containing protein GrpE PF01025.19 KXH54009.1 - 2.1 8.0 9.8 3.9 7.1 1.9 3.2 1 1 1 3 3 3 0 GrpE DUF2730 PF10805.8 KXH54009.1 - 2.3 8.4 11.7 3.5 7.8 0.2 3.9 1 1 1 3 3 3 0 Protein of unknown function (DUF2730) APG6_N PF17675.1 KXH54009.1 - 2.8 8.5 16.1 14 6.2 8.5 2.9 1 1 2 3 3 3 0 Apg6 coiled-coil region Fez1 PF06818.15 KXH54009.1 - 2.9 8.3 18.5 14 6.1 6.0 2.4 1 1 1 2 2 2 0 Fez1 DUF4482 PF14818.6 KXH54009.1 - 4.2 8.2 13.6 0.22 12.4 1.7 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4482) DUF5082 PF16888.5 KXH54009.1 - 4.8 7.5 14.2 0.6 10.4 0.3 3.5 2 1 2 4 4 4 0 Domain of unknown function (DUF5082) RNase_T PF00929.24 KXH54010.1 - 8.6e-06 26.4 0.0 1.3e-05 25.8 0.0 1.3 1 0 0 1 1 1 1 Exonuclease An_peroxidase PF03098.15 KXH54010.1 - 0.19 10.3 0.0 0.34 9.4 0.0 1.3 1 0 0 1 1 1 0 Animal haem peroxidase TPR_2 PF07719.17 KXH54011.1 - 5.8e-24 82.2 5.3 1.3e-06 28.1 0.1 6.0 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_1 PF00515.28 KXH54011.1 - 1.7e-23 81.4 5.3 9.3e-08 31.6 0.0 5.9 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.6 KXH54011.1 - 6.3e-18 63.9 5.7 7.2e-06 26.4 0.0 5.8 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 KXH54011.1 - 1.3e-17 64.1 9.2 2e-06 28.3 2.2 4.4 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 KXH54011.1 - 3.3e-15 55.5 8.6 2.5e-07 30.3 0.0 4.7 3 2 2 5 5 5 3 TPR repeat TPR_8 PF13181.6 KXH54011.1 - 5.7e-15 54.2 0.6 2e-05 24.4 0.0 5.8 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 KXH54011.1 - 1.4e-14 54.3 9.5 0.0003 21.2 1.2 5.2 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 KXH54011.1 - 1.4e-13 50.2 4.3 0.0055 17.0 0.0 5.1 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_7 PF13176.6 KXH54011.1 - 4.5e-13 48.2 3.9 0.032 14.3 0.0 6.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 KXH54011.1 - 2.8e-09 37.0 3.9 0.25 12.1 0.2 6.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.6 KXH54011.1 - 1.3e-08 34.9 2.7 0.015 15.4 0.5 3.6 2 2 1 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KXH54011.1 - 1.3e-08 35.0 9.9 0.00024 21.3 0.4 4.8 3 1 3 6 6 6 4 Tetratricopeptide repeat TPR_20 PF14561.6 KXH54011.1 - 4.2e-07 30.2 9.6 0.004 17.4 0.2 4.6 4 1 1 5 5 4 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KXH54011.1 - 0.0022 18.2 7.6 0.25 11.6 0.5 2.5 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 DUF484 PF04340.12 KXH54011.1 - 0.0046 16.7 0.0 0.011 15.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF484 TPR_15 PF13429.6 KXH54011.1 - 0.023 13.9 9.6 0.14 11.4 0.8 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 KXH54011.1 - 0.024 14.5 0.3 0.024 14.5 0.3 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat NatB_MDM20 PF09797.9 KXH54011.1 - 0.025 13.5 0.0 0.045 12.7 0.0 1.4 1 0 0 1 1 1 0 N-acetyltransferase B complex (NatB) non catalytic subunit DUF4919 PF16266.5 KXH54011.1 - 0.046 13.7 0.1 0.19 11.7 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4919) DUF1641 PF07849.11 KXH54011.1 - 0.1 12.5 0.2 0.24 11.3 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1641) TPR_21 PF09976.9 KXH54011.1 - 1.3 8.7 11.0 8.2 6.1 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat-like domain Cgr1 PF03879.14 KXH54011.1 - 8.2 6.9 8.2 29 5.1 5.1 2.4 2 0 0 2 2 2 0 Cgr1 family Zn_clus PF00172.18 KXH54012.1 - 2.2e-07 30.9 13.1 3.8e-07 30.1 13.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_10 PF13374.6 KXH54068.1 - 1.2e-49 164.9 4.3 4.5e-11 42.3 0.0 6.6 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_12 PF13424.6 KXH54068.1 - 3.3e-45 152.2 7.4 1.6e-15 57.1 0.8 5.9 5 1 1 6 6 5 4 Tetratricopeptide repeat TPR_1 PF00515.28 KXH54068.1 - 8e-26 88.8 18.7 3.8e-05 23.3 0.4 6.9 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_7 PF13176.6 KXH54068.1 - 1.4e-23 81.2 8.9 0.00035 20.4 0.1 7.0 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.6 KXH54068.1 - 8.9e-21 72.3 14.2 0.0021 18.1 0.3 7.1 7 0 0 7 7 6 5 Tetratricopeptide repeat TPR_2 PF07719.17 KXH54068.1 - 1.2e-17 62.5 13.4 0.0061 16.6 0.3 7.0 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_14 PF13428.6 KXH54068.1 - 1.1e-14 53.8 4.9 0.2 12.6 0.0 7.6 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_MalT PF17874.1 KXH54068.1 - 1.2e-14 54.5 1.4 4.8e-14 52.5 0.7 2.2 1 1 1 2 2 2 1 MalT-like TPR region TPR_4 PF07721.14 KXH54068.1 - 6.2e-10 38.7 0.0 0.86 10.4 0.0 6.3 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 KXH54068.1 - 4.4e-08 33.6 8.2 0.18 12.5 0.0 6.6 6 0 0 6 6 6 2 Tetratricopeptide repeat PNP_UDP_1 PF01048.20 KXH54068.1 - 2.8e-07 30.0 0.5 6.5e-07 28.8 0.5 1.6 1 1 0 1 1 1 1 Phosphorylase superfamily TPR_19 PF14559.6 KXH54068.1 - 5.5e-07 30.0 15.2 0.007 16.9 1.5 5.1 3 1 1 5 5 5 3 Tetratricopeptide repeat NB-ARC PF00931.22 KXH54068.1 - 1.5e-06 27.6 0.0 0.037 13.2 0.0 2.3 2 0 0 2 2 2 2 NB-ARC domain TPR_17 PF13431.6 KXH54068.1 - 2.1e-06 27.7 5.4 2.5 8.7 0.1 5.4 5 0 0 5 5 4 2 Tetratricopeptide repeat AAA_16 PF13191.6 KXH54068.1 - 1.3e-05 25.6 0.0 3.4e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain TPR_11 PF13414.6 KXH54068.1 - 0.0018 17.9 11.2 1.4 8.7 0.5 4.9 4 0 0 4 4 4 1 TPR repeat RPN7 PF10602.9 KXH54068.1 - 0.0019 17.9 2.3 1.1 8.9 0.0 3.6 2 1 2 4 4 4 1 26S proteasome subunit RPN7 PPR PF01535.20 KXH54068.1 - 0.015 15.5 0.6 64 4.1 0.0 5.1 5 0 0 5 5 4 0 PPR repeat RPN6_N PF18055.1 KXH54068.1 - 0.031 14.6 1.0 9 6.7 0.1 3.1 1 1 1 3 3 3 0 26S proteasome regulatory subunit RPN6 N-terminal domain AAA_22 PF13401.6 KXH54068.1 - 0.11 12.8 0.0 0.28 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF2225 PF09986.9 KXH54068.1 - 0.36 10.5 5.3 24 4.6 0.5 3.3 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_21 PF09976.9 KXH54068.1 - 0.8 9.4 12.9 4.6 6.9 0.1 4.8 2 1 3 5 5 5 0 Tetratricopeptide repeat-like domain TPR_6 PF13174.6 KXH54068.1 - 0.92 10.3 14.2 1.5e+02 3.4 0.1 6.6 6 0 0 6 6 6 0 Tetratricopeptide repeat RPN6_C_helix PF18503.1 KXH54068.1 - 2.2 8.1 5.0 59 3.5 0.1 4.5 4 0 0 4 4 4 0 26S proteasome subunit RPN6 C-terminal helix domain Rax2 PF12768.7 KXH54073.1 - 5.4e-74 248.3 0.3 5.7e-73 244.9 0.0 2.9 3 0 0 3 3 3 1 Cortical protein marker for cell polarity Syndecan PF01034.20 KXH54073.1 - 0.22 11.5 0.9 0.47 10.4 0.9 1.5 1 0 0 1 1 1 0 Syndecan domain P34-Arc PF04045.14 KXH54074.1 - 2.5e-107 358.1 0.1 3.2e-107 357.7 0.1 1.1 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc DUF4178 PF13785.6 KXH54074.1 - 0.11 12.6 0.0 0.26 11.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4178) WD40 PF00400.32 KXH54075.1 - 1.3e-47 158.8 30.8 8.6e-06 26.4 0.4 11.8 13 0 0 13 13 13 9 WD domain, G-beta repeat Utp12 PF04003.12 KXH54075.1 - 7.1e-19 68.1 0.0 1.4e-18 67.2 0.0 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 KXH54075.1 - 3.6e-15 56.0 5.6 0.0093 16.2 0.1 8.8 5 3 5 10 10 10 5 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KXH54075.1 - 5.4e-05 22.7 0.0 4.5 6.5 0.0 3.4 3 0 0 3 3 3 3 WD40-like domain Nup160 PF11715.8 KXH54075.1 - 0.0011 17.7 4.4 0.26 9.9 0.1 5.0 6 1 0 6 6 6 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 KXH54075.1 - 0.0015 17.3 0.2 0.79 8.4 0.1 4.2 2 2 2 5 5 5 1 Nup133 N terminal like eIF2A PF08662.11 KXH54075.1 - 0.004 17.1 0.2 0.43 10.4 0.0 4.2 4 1 0 4 4 4 1 Eukaryotic translation initiation factor eIF2A Hira PF07569.11 KXH54075.1 - 0.11 12.3 0.1 0.64 9.7 0.0 2.4 2 0 0 2 2 2 0 TUP1-like enhancer of split Alg6_Alg8 PF03155.15 KXH54076.1 - 6.3e-129 431.1 27.9 5.2e-81 273.1 12.7 2.1 2 0 0 2 2 2 2 ALG6, ALG8 glycosyltransferase family BRO1 PF03097.18 KXH54077.1 - 4.5e-12 45.5 0.0 6.2e-12 45.0 0.0 1.2 1 0 0 1 1 1 1 BRO1-like domain Aldedh PF00171.22 KXH54078.1 - 5.9e-125 417.4 0.0 3.3e-124 414.9 0.0 1.8 1 1 0 1 1 1 1 Aldehyde dehydrogenase family CAP_N PF01213.19 KXH54078.1 - 3.1 7.2 5.0 5 6.5 5.0 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal COPIIcoated_ERV PF07970.12 KXH54079.1 - 2.6e-90 302.1 0.2 1.9e-89 299.3 0.1 2.0 2 0 0 2 2 2 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 KXH54079.1 - 3.1e-30 104.4 0.1 1.5e-29 102.2 0.0 2.0 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) CSTF2_hinge PF14327.6 KXH54080.1 - 1.2e-33 115.4 2.5 2.7e-33 114.3 2.5 1.6 1 0 0 1 1 1 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.22 KXH54080.1 - 3e-22 78.2 0.0 5.1e-22 77.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.6 KXH54080.1 - 8.4e-11 41.3 1.2 8.4e-11 41.3 1.2 3.2 4 0 0 4 4 4 1 Transcription termination and cleavage factor C-terminal Spo7_2_N PF15407.6 KXH54080.1 - 0.055 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Sporulation protein family 7 RRM_7 PF16367.5 KXH54080.1 - 0.064 13.4 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif RRM_occluded PF16842.5 KXH54080.1 - 0.15 11.9 0.0 0.36 10.7 0.0 1.6 1 1 0 1 1 1 0 Occluded RNA-recognition motif Sel1 PF08238.12 KXH54081.1 - 3.7e-10 40.2 8.1 0.0051 17.5 0.1 3.6 3 0 0 3 3 3 3 Sel1 repeat Proteasome PF00227.26 KXH54082.1 - 1.3e-47 161.8 0.1 1.5e-47 161.5 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.8 KXH54082.1 - 3.4e-12 45.5 0.1 3.4e-12 45.5 0.1 1.9 3 0 0 3 3 3 1 Proteasome beta subunits C terminal NUP214 PF16755.5 KXH54083.1 - 3.5e-07 29.8 0.0 1.2e-06 28.1 0.0 1.7 1 1 0 1 1 1 1 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 ANAPC4_WD40 PF12894.7 KXH54083.1 - 3.8e-05 23.9 0.0 0.00097 19.4 0.1 3.0 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Syntaxin-6_N PF09177.11 KXH54083.1 - 1.1 9.8 3.3 9.4 6.9 3.1 2.4 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Ribosomal_L35Ae PF01247.18 KXH54084.1 - 3.1e-39 133.0 0.6 4.2e-39 132.6 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 KXH54084.1 - 2.4e-05 24.5 0.1 0.015 15.5 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain G6PD_C PF02781.16 KXH54085.1 - 5.1e-114 380.4 0.0 8.4e-114 379.7 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 KXH54085.1 - 1.7e-60 204.6 0.0 3.2e-60 203.8 0.0 1.4 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Med14 PF08638.11 KXH54086.1 - 2.2e-65 219.7 0.0 4.8e-65 218.6 0.0 1.6 1 0 0 1 1 1 1 Mediator complex subunit MED14 Amino_oxidase PF01593.24 KXH54087.1 - 2.1e-28 99.8 0.0 2.9e-28 99.4 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KXH54087.1 - 2e-13 50.3 0.0 6.2e-13 48.8 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXH54087.1 - 6.8e-08 32.5 0.1 1.5e-06 28.0 0.3 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXH54087.1 - 3.2e-07 29.9 0.1 0.0026 17.0 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXH54087.1 - 0.00042 20.8 2.6 1 10.0 0.0 3.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase MCRA PF06100.11 KXH54087.1 - 0.002 17.0 0.0 0.013 14.3 0.0 2.0 2 0 0 2 2 2 1 MCRA family NAD_binding_9 PF13454.6 KXH54087.1 - 0.002 18.1 0.0 0.11 12.5 0.0 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.17 KXH54087.1 - 0.0034 16.7 0.0 0.0061 15.8 0.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 KXH54087.1 - 0.04 13.0 0.9 0.069 12.2 0.1 1.9 2 0 0 2 2 2 0 FAD binding domain Trp_halogenase PF04820.14 KXH54087.1 - 0.047 12.5 0.0 0.075 11.9 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase BAR_2 PF10455.9 KXH54087.1 - 0.069 12.3 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking Mqo PF06039.15 KXH54087.1 - 0.14 10.6 0.0 0.41 9.1 0.0 1.6 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) zf-CCCH_2 PF14608.6 KXH54088.1 - 6.6e-13 48.6 58.5 2.8e-06 27.6 12.6 5.7 5 1 0 5 5 5 4 RNA-binding, Nab2-type zinc finger Nab2 PF11517.8 KXH54088.1 - 0.008 16.5 0.0 0.015 15.5 0.0 1.4 1 0 0 1 1 1 1 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) Glyco_hydro_20 PF00728.22 KXH54089.1 - 3.1e-85 286.7 0.0 3.9e-85 286.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 KXH54089.1 - 6.8e-32 111.0 0.0 1.3e-31 110.1 0.0 1.5 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 KXH54089.1 - 3e-08 34.5 0.1 1e-06 29.5 0.1 2.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Chlam_OMP6 PF03504.13 KXH54103.1 - 0.036 14.3 0.1 0.045 14.1 0.1 1.1 1 0 0 1 1 1 0 Chlamydia cysteine-rich outer membrane protein 6 GET2 PF08690.10 KXH54167.1 - 4.4 6.9 7.4 8.1 6.0 7.4 1.3 1 0 0 1 1 1 0 GET complex subunit GET2 Glyco_hydro_43 PF04616.14 KXH54168.1 - 5e-36 124.5 0.8 6e-36 124.2 0.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 LRR_10 PF18805.1 KXH54168.1 - 0.029 14.0 0.3 0.11 12.2 0.2 2.0 2 0 0 2 2 2 0 Leucine-rich repeat Na_Ca_ex PF01699.24 KXH54171.1 - 1.7e-07 31.4 13.2 0.0042 17.0 7.5 3.1 1 1 1 2 2 2 2 Sodium/calcium exchanger protein DDDD PF10161.9 KXH54171.1 - 0.11 12.2 0.3 0.33 10.7 0.3 1.8 1 0 0 1 1 1 0 Putative mitochondrial precursor protein Cluap1 PF10234.9 KXH54171.1 - 0.13 11.6 0.0 0.18 11.2 0.0 1.1 1 0 0 1 1 1 0 Clusterin-associated protein-1 Fungal_trans PF04082.18 KXH54172.1 - 4.5e-20 71.8 0.0 1e-19 70.6 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF3295 PF11702.8 KXH54398.1 - 2.6e-59 201.9 23.0 2.6e-59 201.9 23.0 2.7 2 1 0 2 2 2 1 Protein of unknown function (DUF3295) LigD_N PF13298.6 KXH54398.1 - 0.056 13.7 0.1 0.13 12.6 0.1 1.6 1 0 0 1 1 1 0 DNA polymerase Ligase (LigD) InvH PF04741.12 KXH54398.1 - 0.083 12.8 0.5 0.19 11.7 0.5 1.5 1 0 0 1 1 1 0 InvH outer membrane lipoprotein TPR_12 PF13424.6 KXH54401.1 - 0.00016 21.9 3.3 0.06 13.6 0.2 3.9 4 1 0 4 4 4 1 Tetratricopeptide repeat HetR_C PF18460.1 KXH54401.1 - 0.0054 16.6 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 Heterocyst differentiation regulator C-terminal Hood domain TPR_2 PF07719.17 KXH54401.1 - 0.14 12.3 0.6 3 8.2 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 KXH54401.1 - 0.21 11.5 3.6 9.3 6.3 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat EZH2_N PF18601.1 KXH54563.1 - 3.1e-29 101.1 0.1 7.4e-29 99.9 0.1 1.7 1 0 0 1 1 1 1 EZH2 N-terminal domain Ezh2_MCSS PF18600.1 KXH54563.1 - 1.6e-22 78.9 2.9 3.1e-22 77.9 2.9 1.5 1 0 0 1 1 1 1 MCSS domain SET PF00856.28 KXH54563.1 - 6.9e-17 62.3 0.3 5.2e-16 59.5 0.3 2.6 1 1 0 1 1 1 1 SET domain preSET_CXC PF18264.1 KXH54563.1 - 1.2 9.6 37.6 0.89 10.1 28.7 3.4 1 1 1 2 2 2 0 CXC domain Transp_cyt_pur PF02133.15 KXH54564.1 - 4.6e-42 144.3 37.7 5.8e-42 144.0 37.7 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Isochorismatase PF00857.20 KXH54566.1 - 1.1e-26 94.1 0.1 3.1e-25 89.3 0.1 2.6 1 1 0 1 1 1 1 Isochorismatase family ADH_N PF08240.12 KXH54567.1 - 1.7e-27 95.4 2.3 3.7e-27 94.4 2.3 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXH54567.1 - 5.9e-17 61.9 0.0 8.7e-17 61.3 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KXH54567.1 - 1.6e-05 24.5 0.5 0.00083 18.9 0.4 2.4 2 1 0 2 2 2 2 Glucose dehydrogenase C-terminus ATP-synt_G PF04718.15 KXH54568.1 - 1.4e-30 106.1 0.3 4.2e-30 104.5 0.0 1.8 2 0 0 2 2 2 1 Mitochondrial ATP synthase g subunit Rotamase_2 PF13145.6 KXH54568.1 - 0.025 15.4 1.3 0.13 13.1 0.1 2.1 2 0 0 2 2 2 0 PPIC-type PPIASE domain Senescence PF06911.12 KXH54568.1 - 0.05 13.9 7.4 0.12 12.7 7.4 1.6 1 1 0 1 1 1 0 Senescence-associated protein Methyltransf_23 PF13489.6 KXH54569.1 - 8.8e-17 61.4 0.0 1.2e-16 61.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH54569.1 - 1.3e-10 41.9 0.0 3.9e-10 40.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH54569.1 - 3.1e-09 37.4 0.0 6.6e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH54569.1 - 3.6e-07 30.1 0.0 2.9e-06 27.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH54569.1 - 1.7e-05 25.5 0.0 0.00012 22.8 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXH54569.1 - 0.00014 21.3 0.0 0.0004 19.8 0.0 1.7 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.15 KXH54569.1 - 0.044 13.6 0.0 7 6.4 0.0 2.3 2 0 0 2 2 2 0 Hypothetical methyltransferase FtsJ PF01728.19 KXH54569.1 - 0.18 11.9 0.0 0.26 11.4 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase TFIIA PF03153.13 KXH54570.1 - 4.6e-90 303.6 9.2 7.3e-90 302.9 9.2 1.3 1 1 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit ANAPC4_WD40 PF12894.7 KXH54571.1 - 1.6e-17 63.6 5.2 3.3e-05 24.1 0.1 4.4 3 1 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KXH54571.1 - 1.8e-16 60.2 18.3 0.00033 21.4 0.1 6.6 7 0 0 7 7 7 5 WD domain, G-beta repeat Ge1_WD40 PF16529.5 KXH54571.1 - 2.8e-06 26.5 0.1 0.00034 19.7 0.0 3.3 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KXH54571.1 - 3.7e-06 27.0 0.2 0.00059 19.8 0.1 2.6 1 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Kelch_4 PF13418.6 KXH54572.1 - 2.6e-25 88.2 10.7 9.1e-09 35.2 0.0 4.9 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_6 PF13964.6 KXH54572.1 - 6e-22 77.1 4.4 7.7e-05 22.8 0.0 5.1 3 1 2 5 5 5 4 Kelch motif Kelch_5 PF13854.6 KXH54572.1 - 9.4e-22 76.6 3.9 1.5e-06 28.0 0.0 4.8 4 0 0 4 4 4 4 Kelch motif Kelch_1 PF01344.25 KXH54572.1 - 1.3e-19 69.5 1.6 0.00012 21.6 0.0 4.9 5 0 0 5 5 5 3 Kelch motif Kelch_3 PF13415.6 KXH54572.1 - 1.1e-17 63.8 3.2 1.2e-06 28.7 0.1 5.2 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_2 PF07646.15 KXH54572.1 - 8e-16 57.3 5.2 0.0019 18.1 0.0 4.8 4 0 0 4 4 4 4 Kelch motif BTB PF00651.31 KXH54572.1 - 1.9e-09 37.7 0.0 3.3e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 KXH54572.1 - 0.027 14.6 0.0 0.052 13.6 0.0 1.4 1 0 0 1 1 1 0 BTB And C-terminal Kelch zf-C2H2 PF00096.26 KXH54573.1 - 0.00081 19.7 5.7 0.23 12.0 0.4 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_aberr PF17017.5 KXH54573.1 - 0.0021 18.2 1.3 1.4 9.0 0.1 2.3 2 0 0 2 2 2 2 Aberrant zinc-finger zf-H2C2_2 PF13465.6 KXH54573.1 - 0.0098 16.3 9.3 0.089 13.3 0.5 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KXH54573.1 - 0.032 15.0 10.3 0.13 13.2 0.6 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger HIG_1_N PF04588.13 KXH54575.1 - 6.3e-05 23.1 1.7 0.00018 21.7 1.7 1.8 1 0 0 1 1 1 1 Hypoxia induced protein conserved region DUF4079 PF13301.6 KXH54575.1 - 0.042 14.0 0.6 0.063 13.4 0.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4079) Kelch_1 PF01344.25 KXH54576.1 - 2.5e-41 139.0 14.9 1.2e-08 34.4 0.3 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_5 PF13854.6 KXH54576.1 - 2.2e-40 136.1 13.2 6.2e-07 29.3 0.1 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 KXH54576.1 - 5.8e-39 131.7 19.4 3.7e-09 36.6 0.0 6.8 7 0 0 7 7 7 6 Galactose oxidase, central domain Kelch_4 PF13418.6 KXH54576.1 - 2.1e-36 123.6 15.7 4.2e-07 29.9 0.1 6.4 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_6 PF13964.6 KXH54576.1 - 6.4e-34 115.1 15.5 4.6e-07 29.9 0.0 6.5 4 2 2 6 6 6 6 Kelch motif Kelch_2 PF07646.15 KXH54576.1 - 5.1e-32 108.6 15.8 9e-07 28.6 0.0 6.5 6 0 0 6 6 6 6 Kelch motif Ank_2 PF12796.7 KXH54577.1 - 2.1e-13 50.6 0.1 0.0003 21.3 0.0 3.5 3 1 1 4 4 4 2 Ankyrin repeats (3 copies) Ank PF00023.30 KXH54577.1 - 1.2e-07 31.8 2.8 0.31 11.6 0.1 5.3 7 0 0 7 7 7 2 Ankyrin repeat Ank_5 PF13857.6 KXH54577.1 - 4.7e-07 30.0 2.0 0.22 11.9 0.1 4.7 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXH54577.1 - 0.00099 19.6 2.5 0.066 13.8 0.1 4.2 4 2 1 5 5 5 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXH54577.1 - 0.0037 17.6 5.8 21 6.1 0.0 5.6 6 1 0 6 6 6 1 Ankyrin repeat Helo_like_N PF17111.5 KXH54578.1 - 4.2e-06 26.3 0.8 4.2e-06 26.3 0.8 1.8 2 0 0 2 2 2 1 Fungal N-terminal domain of STAND proteins NACHT PF05729.12 KXH54578.1 - 7.6e-06 25.9 0.0 2e-05 24.5 0.0 1.7 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KXH54578.1 - 1.9e-05 25.1 0.1 0.00012 22.5 0.0 2.2 2 1 0 2 2 2 1 AAA ATPase domain CinA_KH PF18146.1 KXH54578.1 - 0.0031 17.6 2.7 0.085 13.0 0.7 3.2 3 1 0 3 3 3 1 Damage-inducible protein CinA KH domain AAA_22 PF13401.6 KXH54578.1 - 0.0041 17.4 0.0 0.016 15.5 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA PF00004.29 KXH54578.1 - 0.085 13.3 1.8 0.48 10.8 0.5 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF1479 PF07350.12 KXH54579.1 - 2.6e-161 537.0 0.0 3.3e-161 536.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) HHH PF00633.23 KXH54580.1 - 0.018 14.9 0.3 0.046 13.6 0.3 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif HHH_5 PF14520.6 KXH54580.1 - 0.057 14.0 0.1 0.71 10.5 0.0 2.5 2 0 0 2 2 2 0 Helix-hairpin-helix domain Ribosomal_60s PF00428.19 KXH54580.1 - 0.61 10.7 3.4 1.3 9.6 1.2 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein zf-met2 PF12907.7 KXH54581.1 - 3.9e-16 58.9 3.1 6.3e-16 58.2 3.1 1.3 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.14 KXH54581.1 - 7.7e-06 26.7 8.5 7.7e-06 26.7 8.5 1.5 2 0 0 2 2 2 1 4F5 protein family DIOX_N PF14226.6 KXH54582.1 - 4.4e-33 114.5 0.0 1.3e-31 109.8 0.0 2.2 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KXH54582.1 - 4.5e-13 49.5 0.0 1e-12 48.4 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily GxGYxYP_C PF14323.6 KXH54582.1 - 0.035 14.0 0.0 0.054 13.4 0.0 1.2 1 0 0 1 1 1 0 GxGYxYP putative glycoside hydrolase C-terminal domain WD40 PF00400.32 KXH54583.1 - 8.4e-08 32.8 14.6 0.02 15.8 0.3 7.2 8 0 0 8 8 8 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXH54583.1 - 5.3e-07 29.8 0.1 1.9 8.8 0.0 5.7 5 1 0 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ PF01011.21 KXH54583.1 - 0.029 14.3 0.0 0.18 11.8 0.0 2.5 1 0 0 1 1 1 0 PQQ enzyme repeat PD40 PF07676.12 KXH54583.1 - 0.033 14.1 0.2 22 5.1 0.0 4.1 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat RNA_pol_N PF01194.17 KXH54584.1 - 4.9e-31 106.8 0.9 5.7e-31 106.6 0.9 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Chordopox_RPO7 PF05864.12 KXH54584.1 - 0.096 12.9 0.6 0.16 12.3 0.6 1.4 1 1 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) 7TMR-HDED PF07697.11 KXH54585.1 - 0.27 11.3 2.1 9.7 6.2 0.8 2.7 2 1 1 3 3 3 0 7TM-HD extracellular Methyltransf_16 PF10294.9 KXH54586.1 - 6.6e-19 68.3 0.0 1.2e-18 67.5 0.0 1.4 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 KXH54586.1 - 0.0095 15.8 0.0 0.016 15.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH54586.1 - 0.019 15.7 0.0 0.055 14.2 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 KXH54586.1 - 0.036 13.5 0.0 0.063 12.7 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KXH54586.1 - 0.039 13.5 0.0 0.094 12.3 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase small domain Dynein_light PF01221.18 KXH54589.1 - 2.3e-39 133.6 1.3 2.6e-39 133.4 1.3 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 SGTA_dimer PF16546.5 KXH54589.1 - 0.033 14.0 0.5 0.048 13.5 0.5 1.2 1 0 0 1 1 1 0 Homodimerisation domain of SGTA RRM_1 PF00076.22 KXH54590.1 - 1.8e-77 255.1 1.7 3.7e-18 65.1 0.0 5.5 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KXH54590.1 - 4.3e-09 36.1 0.0 0.14 12.1 0.0 4.6 5 0 0 5 5 5 3 Occluded RNA-recognition motif Limkain-b1 PF11608.8 KXH54590.1 - 1.9e-06 27.8 0.3 0.69 10.0 0.0 5.8 5 1 0 5 5 5 1 Limkain b1 RRM_7 PF16367.5 KXH54590.1 - 3.5e-06 27.0 0.1 6.8 6.9 0.0 5.0 5 0 0 5 5 5 2 RNA recognition motif Nup35_RRM_2 PF14605.6 KXH54590.1 - 7.8e-06 25.8 0.0 0.98 9.5 0.0 4.3 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 KXH54590.1 - 1.7e-05 24.8 2.9 1.3 9.1 0.0 5.4 6 0 0 6 6 6 1 RNA binding motif Smg4_UPF3 PF03467.15 KXH54590.1 - 2e-05 24.7 1.5 0.0024 17.9 0.3 3.6 3 0 0 3 3 3 1 Smg-4/UPF3 family RRM_Rrp7 PF17799.1 KXH54590.1 - 0.004 17.0 0.0 19 5.0 0.0 4.1 4 0 0 4 4 4 0 Rrp7 RRM-like N-terminal domain RRM_2 PF04059.12 KXH54590.1 - 0.04 14.1 0.0 1.7 8.9 0.0 3.1 3 0 0 3 3 3 0 RNA recognition motif 2 Peptidase_C26 PF07722.13 KXH54590.1 - 0.15 11.8 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 Peptidase C26 SET_assoc PF11767.8 KXH54590.1 - 0.17 11.5 0.0 13 5.6 0.0 3.5 4 0 0 4 4 4 0 Histone lysine methyltransferase SET associated PHM7_cyt PF14703.6 KXH54590.1 - 0.89 9.8 10.7 14 5.9 0.1 6.1 5 3 0 6 6 6 0 Cytosolic domain of 10TM putative phosphate transporter TEA PF01285.18 KXH54591.1 - 9.1e-27 92.9 0.3 2e-26 91.8 0.3 1.6 1 0 0 1 1 1 1 TEA/ATTS domain Pro_isomerase PF00160.21 KXH54593.1 - 9.6e-48 162.4 0.2 1.2e-47 162.1 0.2 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF5545 PF17699.1 KXH54593.1 - 0.052 13.4 0.1 1.7 8.4 0.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5545) Thioredoxin_3 PF13192.6 KXH54593.1 - 0.14 12.2 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin domain DIX PF00778.17 KXH54593.1 - 0.17 11.8 0.0 0.39 10.6 0.0 1.6 1 0 0 1 1 1 0 DIX domain HET PF06985.11 KXH54966.1 - 6.1e-13 49.4 0.3 1.4e-12 48.2 0.3 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF2268 PF10026.9 KXH54966.1 - 0.019 14.5 0.1 0.032 13.8 0.1 1.3 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) FOXP-CC PF16159.5 KXH54966.1 - 0.092 13.4 0.5 0.4 11.3 0.5 2.2 1 1 0 1 1 1 0 FOXP coiled-coil domain tRNA-synt_1b PF00579.25 KXH54978.1 - 1.7e-59 201.6 0.0 2.1e-59 201.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) PNP_UDP_1 PF01048.20 KXH54979.1 - 1.5e-40 138.9 0.3 2e-40 138.5 0.3 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily Med13_C PF06333.12 KXH54980.1 - 8.3e-92 308.0 0.2 8.3e-92 308.0 0.2 2.3 2 0 0 2 2 2 1 Mediator complex subunit 13 C-terminal domain Med13_N PF11597.8 KXH54980.1 - 2e-27 96.4 0.9 3.9e-27 95.5 0.9 1.5 1 0 0 1 1 1 1 Mediator complex subunit 13 N-terminal MID_MedPIWI PF18296.1 KXH54980.1 - 1e-13 51.7 0.6 4.6e-06 26.6 0.0 3.0 3 0 0 3 3 3 2 MID domain of medPIWI DUF499 PF04465.12 KXH54980.1 - 0.29 8.8 0.0 0.54 7.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF499) TMA7 PF09072.10 KXH54980.1 - 1.2 10.0 3.7 1.6 9.6 0.2 2.3 2 0 0 2 2 2 0 Translation machinery associated TMA7 NUC153 PF08159.12 KXH54981.1 - 1.3e-11 44.1 3.2 2.9e-11 43.0 3.2 1.7 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.32 KXH54981.1 - 4.7e-05 24.1 0.1 7.4 7.6 0.0 4.1 4 0 0 4 4 4 2 WD domain, G-beta repeat TMEM210 PF15195.6 KXH54982.1 - 0.033 14.6 0.3 0.047 14.1 0.3 1.2 1 0 0 1 1 1 0 TMEM210 family DUF2371 PF10177.9 KXH54982.1 - 0.051 13.7 0.0 0.068 13.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) DUF3918 PF13056.6 KXH54982.1 - 0.052 13.2 0.2 0.085 12.5 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3918) Ribosomal_L33 PF00471.20 KXH54984.1 - 7.7e-06 26.3 0.0 1.1e-05 25.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L33 Aminotran_1_2 PF00155.21 KXH54985.1 - 1.2e-38 133.2 0.0 1.7e-38 132.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KXH54985.1 - 0.07 11.6 0.0 0.12 10.9 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme RPN7 PF10602.9 KXH54986.1 - 1.4e-56 191.0 2.2 1.4e-56 190.9 0.5 1.8 2 0 0 2 2 2 1 26S proteasome subunit RPN7 PCI PF01399.27 KXH54986.1 - 1.3e-15 57.8 0.0 3e-15 56.6 0.0 1.6 1 0 0 1 1 1 1 PCI domain TPR_14 PF13428.6 KXH54986.1 - 0.089 13.7 1.5 2.5 9.1 0.1 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Pox_MCEL PF03291.16 KXH54987.1 - 5.7e-71 239.3 0.0 4.1e-48 164.2 0.0 2.3 2 0 0 2 2 2 2 mRNA capping enzyme Methyltransf_25 PF13649.6 KXH54987.1 - 8.7e-11 42.4 0.1 9.8e-05 23.0 0.0 2.7 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 KXH54987.1 - 4.6e-09 36.9 0.1 0.0031 18.2 0.0 3.1 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_11 PF08241.12 KXH54987.1 - 2.7e-07 31.2 0.1 0.029 15.0 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 KXH54987.1 - 3.8e-06 26.8 0.0 0.00085 19.1 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 KXH54987.1 - 8.4e-06 25.7 0.0 1.7e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 KXH54987.1 - 0.00027 20.2 0.0 0.00043 19.6 0.0 1.2 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family Methyltransf_9 PF08003.11 KXH54987.1 - 0.17 10.8 0.0 0.38 9.6 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) DDRGK PF09756.9 KXH54987.1 - 7.2 6.2 12.2 0.58 9.7 1.5 2.5 2 0 0 2 2 2 0 DDRGK domain bZIP_1 PF00170.21 KXH54990.1 - 0.082 13.0 1.7 0.23 11.6 1.7 1.8 1 0 0 1 1 1 0 bZIP transcription factor CENP-H PF05837.12 KXH54990.1 - 0.79 10.2 7.5 1.5 9.3 7.5 1.4 1 0 0 1 1 1 0 Centromere protein H (CENP-H) CorA PF01544.18 KXH54992.1 - 8.9e-06 25.2 0.7 1.3e-05 24.7 0.7 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein APH PF01636.23 KXH54994.1 - 1.5e-10 41.5 1.4 2.1e-06 27.8 0.0 3.4 3 1 0 3 3 3 2 Phosphotransferase enzyme family Choline_kinase PF01633.20 KXH54994.1 - 1.5e-06 28.0 0.0 3.2e-06 26.9 0.0 1.4 1 1 0 1 1 1 1 Choline/ethanolamine kinase AF-4 PF05110.13 KXH54994.1 - 0.00066 17.9 11.1 0.00092 17.5 11.1 1.1 1 0 0 1 1 1 1 AF-4 proto-oncoprotein RAP1 PF07218.11 KXH54994.1 - 2.8 6.1 7.1 3.9 5.6 7.1 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Med12 PF09497.10 KXH54995.1 - 1.8e-28 98.6 0.4 1.1e-27 96.1 0.4 2.4 2 0 0 2 2 2 1 Transcription mediator complex subunit Med12 Med12-LCEWAV PF12145.8 KXH54995.1 - 0.18 10.6 0.0 15 4.3 0.0 2.3 2 0 0 2 2 2 0 Eukaryotic Mediator 12 subunit domain UPF0139 PF03669.13 KXH54996.1 - 1.7e-07 31.0 0.0 2.3e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) ATP_transf PF09830.9 KXH54997.1 - 2.7e-13 49.8 0.1 5.6e-13 48.8 0.1 1.6 1 0 0 1 1 1 1 ATP adenylyltransferase MOSC PF03473.17 KXH54998.1 - 6.1e-22 78.0 0.0 1e-21 77.3 0.0 1.3 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 KXH54998.1 - 2.9e-12 46.5 0.0 5.4e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MFS_1 PF07690.16 KXH54999.1 - 6.1e-33 114.2 42.7 6.1e-33 114.2 42.7 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH54999.1 - 3.3e-07 29.5 29.7 1.4e-06 27.4 9.4 2.7 2 1 0 2 2 2 2 Sugar (and other) transporter Tyrosinase PF00264.20 KXH55000.1 - 2e-34 119.9 5.7 2.2e-33 116.4 5.7 2.1 1 1 0 1 1 1 1 Common central domain of tyrosinase TPR_12 PF13424.6 KXH55001.1 - 1.2e-17 64.0 13.5 2e-06 28.0 0.1 6.1 4 2 1 5 5 5 5 Tetratricopeptide repeat TPR_2 PF07719.17 KXH55001.1 - 8.1e-10 38.1 10.8 3.2 8.1 0.4 7.6 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_MalT PF17874.1 KXH55001.1 - 1.3e-09 37.9 9.4 2.5e-07 30.4 3.1 2.3 1 1 1 2 2 2 2 MalT-like TPR region TPR_10 PF13374.6 KXH55001.1 - 4.3e-09 36.0 13.6 1.5 8.8 0.0 8.1 9 0 0 9 9 7 3 Tetratricopeptide repeat TPR_7 PF13176.6 KXH55001.1 - 5.4e-08 32.3 8.6 1.8 8.7 0.0 7.0 7 0 0 7 7 6 1 Tetratricopeptide repeat DUF676 PF05057.14 KXH55001.1 - 1.3e-05 24.9 0.0 3.2e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Putative serine esterase (DUF676) TPR_19 PF14559.6 KXH55001.1 - 2.1e-05 24.9 15.3 0.24 11.9 0.0 6.4 2 1 6 8 8 8 3 Tetratricopeptide repeat TPR_14 PF13428.6 KXH55001.1 - 3.5e-05 24.3 9.2 2.3 9.3 0.1 6.2 7 0 0 7 7 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 KXH55001.1 - 4e-05 23.2 11.4 1.1 9.2 0.1 6.6 7 0 0 7 7 7 1 Tetratricopeptide repeat Abhydrolase_6 PF12697.7 KXH55001.1 - 0.00018 22.2 0.1 0.00035 21.2 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family AAA_22 PF13401.6 KXH55001.1 - 0.00043 20.6 0.0 0.0019 18.5 0.0 2.1 2 0 0 2 2 1 1 AAA domain PGAP1 PF07819.13 KXH55001.1 - 0.00055 19.7 0.0 0.0012 18.6 0.0 1.6 1 0 0 1 1 1 1 PGAP1-like protein TPR_8 PF13181.6 KXH55001.1 - 0.00062 19.8 6.9 24 5.5 0.0 7.1 7 0 0 7 7 7 0 Tetratricopeptide repeat Abhydrolase_8 PF06259.12 KXH55001.1 - 0.0011 18.6 0.0 0.0023 17.6 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase DUF829 PF05705.14 KXH55001.1 - 0.0039 17.1 0.0 0.01 15.7 0.0 1.7 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) TPR_16 PF13432.6 KXH55001.1 - 0.0067 17.1 7.8 0.62 10.8 0.2 4.3 3 1 1 4 4 3 1 Tetratricopeptide repeat TPR_3 PF07720.12 KXH55001.1 - 0.0079 16.2 0.2 0.13 12.3 0.0 2.8 3 0 0 3 3 2 1 Tetratricopeptide repeat NB-ARC PF00931.22 KXH55001.1 - 0.011 15.0 0.0 0.47 9.6 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain TPR_4 PF07721.14 KXH55001.1 - 0.011 16.2 4.0 0.5 11.1 0.4 4.5 4 0 0 4 4 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KXH55001.1 - 0.02 15.1 6.2 12 6.2 0.5 4.8 3 1 2 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 Palm_thioest PF02089.15 KXH55001.1 - 0.036 13.9 0.0 0.068 13.0 0.0 1.5 1 0 0 1 1 1 0 Palmitoyl protein thioesterase TPR_6 PF13174.6 KXH55001.1 - 0.036 14.7 9.4 1.7 9.4 0.1 6.0 6 0 0 6 6 5 0 Tetratricopeptide repeat LCAT PF02450.15 KXH55001.1 - 0.12 11.6 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase PPR PF01535.20 KXH55001.1 - 0.43 10.9 2.8 7.4 7.1 0.0 3.7 4 0 0 4 4 3 0 PPR repeat TPR_17 PF13431.6 KXH55001.1 - 0.79 10.2 2.8 26 5.5 0.0 4.7 6 0 0 6 6 5 0 Tetratricopeptide repeat AAA_16 PF13191.6 KXH55001.1 - 0.95 9.8 0.0 0.95 9.8 0.0 4.0 4 2 1 5 5 4 0 AAA ATPase domain Glyco_hydro_17 PF00332.18 KXH55003.1 - 1.6e-34 119.9 0.1 4.3e-33 115.2 0.1 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 Asp PF00026.23 KXH55004.1 - 3.4e-58 197.5 3.3 4.2e-58 197.3 3.3 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KXH55004.1 - 3.6e-14 53.4 0.8 2.6e-13 50.6 0.4 2.5 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.6 KXH55004.1 - 2.3e-05 24.9 0.0 0.22 12.1 0.0 3.4 2 2 0 2 2 2 2 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KXH55004.1 - 0.00022 21.8 0.1 0.94 10.2 0.0 3.1 2 1 0 2 2 2 2 Aspartyl protease ADH_zinc_N PF00107.26 KXH55006.1 - 3.1e-22 78.9 0.1 4.6e-22 78.4 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXH55006.1 - 2.9e-18 65.8 0.0 6.3e-18 64.6 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KXH55006.1 - 9.5e-09 36.4 0.0 1.7e-08 35.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase IGFBP PF00219.18 KXH55006.1 - 0.0086 16.7 2.5 0.01 16.5 0.3 2.1 2 0 0 2 2 2 1 Insulin-like growth factor binding protein Methyltransf_32 PF13679.6 KXH55006.1 - 0.02 14.9 0.0 0.032 14.2 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 KXH55007.1 - 8.2e-19 68.0 0.0 1.1e-18 67.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH55007.1 - 2.4e-11 44.2 0.0 9.7e-11 42.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH55007.1 - 6.3e-09 36.4 0.0 3.7e-08 33.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH55007.1 - 1.7e-08 34.4 0.0 2.8e-07 30.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH55007.1 - 2.5e-07 31.4 0.0 1.6e-06 28.7 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KXH55007.1 - 0.002 17.6 0.0 0.03 13.8 0.0 2.2 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.14 KXH55007.1 - 0.01 15.4 0.0 0.03 13.9 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase small domain CMAS PF02353.20 KXH55007.1 - 0.013 14.8 0.0 0.025 13.9 0.0 1.4 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase PQ-loop PF04193.14 KXH55008.1 - 3.7e-40 135.5 6.7 6.2e-21 73.9 0.1 2.8 2 0 0 2 2 2 2 PQ loop repeat TMEM132D_C PF15706.5 KXH55008.1 - 0.055 13.2 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term ER_lumen_recept PF00810.18 KXH55008.1 - 0.27 12.0 1.8 8.8 7.1 0.1 2.9 2 2 2 4 4 4 0 ER lumen protein retaining receptor S1-P1_nuclease PF02265.16 KXH55009.1 - 1e-70 238.4 0.1 1.2e-70 238.2 0.1 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease Msg2_C PF12373.8 KXH55011.1 - 0.062 12.7 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Major surface glycoprotein 2 C terminal p450 PF00067.22 KXH55012.1 - 4.7e-46 157.5 0.0 1.4e-43 149.3 0.0 2.1 1 1 0 1 1 1 1 Cytochrome P450 4HBT PF03061.22 KXH55013.1 - 9.4e-06 25.9 0.0 1.6e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.6 KXH55013.1 - 0.047 13.8 0.1 0.088 12.9 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4442) F-box-like PF12937.7 KXH55014.1 - 7.4e-08 32.2 0.4 1.8e-07 31.0 0.4 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXH55014.1 - 2.4e-07 30.5 1.4 5.4e-07 29.3 0.3 2.1 2 0 0 2 2 2 1 F-box domain Bac_rhamnosid6H PF17389.2 KXH55015.1 - 8.6e-14 51.5 2.5 5.5e-12 45.6 2.5 2.1 2 0 0 2 2 2 2 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Glyco_hydro_36 PF17167.4 KXH55015.1 - 0.0045 15.7 0.1 0.0098 14.6 0.1 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase 36 superfamily, catalytic domain GDE_C PF06202.14 KXH55015.1 - 0.0095 14.9 0.1 0.17 10.8 0.0 2.0 2 0 0 2 2 2 1 Amylo-alpha-1,6-glucosidase CFEM PF05730.11 KXH55016.1 - 1.1e-13 51.0 8.8 2.1e-13 50.1 8.8 1.5 1 0 0 1 1 1 1 CFEM domain GMC_oxred_N PF00732.19 KXH55017.1 - 1.1e-25 90.7 0.0 7.7e-18 64.9 0.0 3.1 2 1 0 3 3 3 3 GMC oxidoreductase GMC_oxred_C PF05199.13 KXH55017.1 - 6.5e-21 75.4 0.0 1.1e-20 74.6 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KXH55017.1 - 0.00012 22.2 0.2 0.00062 20.0 0.2 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXH55017.1 - 0.00014 21.2 0.0 0.00026 20.3 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KXH55017.1 - 0.0054 16.0 0.1 0.0079 15.5 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 KXH55017.1 - 0.0073 15.4 0.2 0.01 14.9 0.2 1.1 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 KXH55017.1 - 0.013 14.7 0.2 0.028 13.5 0.2 1.5 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 KXH55017.1 - 0.02 14.1 0.8 4.1 6.6 0.0 2.6 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXH55017.1 - 0.075 11.7 0.1 0.11 11.2 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein NinD PF17466.2 KXH55018.1 - 0.0021 18.1 1.2 0.59 10.3 0.1 2.4 2 0 0 2 2 2 2 Family of unknown function EI24 PF07264.11 KXH55019.1 - 2.9e-14 53.7 3.2 4.5e-14 53.1 3.2 1.3 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Dioxygenase_C PF00775.21 KXH55022.1 - 6.6e-45 152.8 0.0 1e-44 152.2 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 KXH55022.1 - 1.9e-30 104.6 0.0 3.5e-30 103.7 0.0 1.5 1 0 0 1 1 1 1 Catechol dioxygenase N terminus Big_1 PF02369.16 KXH55022.1 - 0.05 13.6 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 1) CarboxypepD_reg PF13620.6 KXH55022.1 - 0.068 13.4 0.0 0.2 11.9 0.0 1.8 1 1 0 1 1 1 0 Carboxypeptidase regulatory-like domain SUI1 PF01253.22 KXH55023.1 - 1e-26 93.3 3.8 1.4e-26 92.8 3.8 1.2 1 0 0 1 1 1 1 Translation initiation factor SUI1 EOS1 PF12326.8 KXH55024.1 - 2.5e-14 53.6 3.4 1.7e-13 50.9 0.7 2.1 1 1 1 2 2 2 2 N-glycosylation protein MBA1 PF07961.11 KXH55025.1 - 6.5e-11 41.7 0.4 8.6e-11 41.3 0.4 1.2 1 0 0 1 1 1 1 MBA1-like protein Tim44 PF04280.15 KXH55025.1 - 2.3e-07 31.0 0.0 5.3e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 Tim44-like domain SSF PF00474.17 KXH55026.1 - 9e-08 31.4 34.8 1.3e-06 27.5 34.8 2.2 1 1 0 1 1 1 1 Sodium:solute symporter family Sel1 PF08238.12 KXH55029.1 - 5.2e-49 163.6 23.3 9.6e-09 35.6 0.1 7.8 7 0 0 7 7 7 7 Sel1 repeat FIST_C PF10442.9 KXH55029.1 - 0.0066 16.4 0.1 0.017 15.1 0.0 1.6 2 0 0 2 2 2 1 FIST C domain CHASE3 PF05227.13 KXH55029.1 - 1.4 8.9 3.8 3.8 7.4 1.6 2.2 2 0 0 2 2 2 0 CHASE3 domain CBP4 PF07960.11 KXH55030.1 - 3.4e-28 98.1 1.1 4.4e-28 97.7 1.1 1.1 1 0 0 1 1 1 1 CBP4 COQ7 PF03232.13 KXH55030.1 - 0.011 15.6 0.0 0.013 15.3 0.0 1.1 1 0 0 1 1 1 0 Ubiquinone biosynthesis protein COQ7 DUF3854 PF12965.7 KXH55030.1 - 0.069 13.1 1.5 0.11 12.5 1.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3854) NAC PF01849.18 KXH55031.1 - 1.9e-24 85.4 0.3 8.3e-24 83.3 0.1 2.0 2 0 0 2 2 2 1 NAC domain A_deamin PF02137.18 KXH55032.1 - 8.7e-32 110.9 0.0 1e-31 110.6 0.0 1.1 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain Ribosomal_L24e PF01246.20 KXH55033.1 - 4.2e-28 97.4 0.1 4.2e-28 97.4 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein L24e Redoxin PF08534.10 KXH55034.1 - 1.3e-34 119.1 0.0 1.4e-34 118.9 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 KXH55034.1 - 9.3e-09 35.3 0.1 1.2e-08 34.9 0.1 1.1 1 0 0 1 1 1 1 AhpC/TSA family N6_Mtase PF02384.16 KXH55034.1 - 0.065 12.5 0.0 0.088 12.1 0.0 1.1 1 0 0 1 1 1 0 N-6 DNA Methylase FAM163 PF15069.6 KXH55034.1 - 0.15 12.5 0.0 0.2 12.1 0.0 1.2 1 0 0 1 1 1 0 FAM163 family DUF1348 PF07080.11 KXH55035.1 - 1.3e-64 215.9 10.8 1.5e-64 215.7 10.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) SnoaL_2 PF12680.7 KXH55035.1 - 1.8e-06 28.5 0.5 2.7e-06 27.9 0.5 1.3 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 KXH55035.1 - 0.0094 16.3 0.0 0.014 15.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) TAD2 PF18521.1 KXH55035.1 - 0.11 12.5 0.8 2.5 8.2 0.1 2.9 2 0 0 2 2 2 0 Transactivation domain 2 RGS PF00615.19 KXH55036.1 - 9.4e-05 22.7 0.1 0.027 14.8 0.0 2.3 2 0 0 2 2 2 2 Regulator of G protein signaling domain Pox_A14 PF05767.12 KXH55036.1 - 0.0044 17.1 0.1 0.01 16.0 0.1 1.6 1 0 0 1 1 1 1 Poxvirus virion envelope protein A14 DUF1170 PF06663.13 KXH55038.1 - 0.031 14.0 0.1 0.039 13.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1170) Nop14 PF04147.12 KXH55039.1 - 0.0036 15.6 19.4 0.0048 15.2 19.4 1.1 1 0 0 1 1 1 1 Nop14-like family SAPS PF04499.15 KXH55039.1 - 0.037 12.8 1.0 0.046 12.5 1.0 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CDC45 PF02724.14 KXH55039.1 - 0.045 12.1 15.0 0.06 11.6 15.0 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 KXH55039.1 - 0.093 12.1 22.7 0.13 11.7 22.7 1.1 1 0 0 1 1 1 0 SDA1 THEG PF14912.6 KXH55039.1 - 0.095 13.2 0.1 0.18 12.3 0.1 1.5 1 0 0 1 1 1 0 Testicular haploid expressed repeat Mpp10 PF04006.12 KXH55039.1 - 1 7.7 20.2 1.4 7.3 20.2 1.1 1 0 0 1 1 1 0 Mpp10 protein TFIIF_alpha PF05793.12 KXH55039.1 - 2 6.9 19.3 2.7 6.5 19.3 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) RRN3 PF05327.11 KXH55039.1 - 2.8 6.4 18.8 4.1 5.8 18.8 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 YL1 PF05764.13 KXH55039.1 - 3 7.9 24.2 5.5 7.0 24.2 1.4 1 0 0 1 1 1 0 YL1 nuclear protein OKR_DC_1_C PF03711.15 KXH55101.1 - 0.042 14.2 0.1 0.064 13.5 0.1 1.2 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, C-terminal domain GATase_6 PF13522.6 KXH55102.1 - 6e-14 52.4 0.0 1.3e-13 51.3 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 KXH55102.1 - 4.5e-13 49.2 0.0 1.2e-12 47.8 0.0 1.7 2 0 0 2 2 2 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 KXH55102.1 - 6.5e-09 35.5 0.1 1.3e-08 34.5 0.1 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.6 KXH55102.1 - 0.00016 20.7 0.0 0.00029 19.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Stc1 PF12898.7 KXH55103.1 - 2.6e-20 72.7 3.2 4.8e-20 71.9 3.2 1.4 1 0 0 1 1 1 1 Stc1 domain BCDHK_Adom3 PF10436.9 KXH55104.1 - 2.4e-76 255.1 0.0 3.4e-76 254.6 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KXH55104.1 - 6.6e-13 49.2 0.0 1.2e-12 48.3 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KXH55104.1 - 0.069 13.0 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase NBP1 PF08537.10 KXH55105.1 - 0.53 9.6 4.9 0.11 11.8 0.9 1.8 2 0 0 2 2 2 0 Fungal Nap binding protein NBP1 Tropomyosin_1 PF12718.7 KXH55105.1 - 0.66 10.1 7.1 0.11 12.7 3.3 1.6 2 0 0 2 2 2 0 Tropomyosin like PilJ PF13675.6 KXH55105.1 - 7.7 6.6 7.2 0.8 9.7 0.5 2.6 3 0 0 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term Alpha-amylase PF00128.24 KXH55106.1 - 5.1e-48 164.4 0.0 1.2e-47 163.1 0.0 1.6 1 1 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.11 KXH55106.1 - 1.2e-12 47.9 0.0 2.7e-12 46.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) SH3_2 PF07653.17 KXH55106.1 - 0.039 13.6 0.0 0.073 12.8 0.0 1.4 1 0 0 1 1 1 0 Variant SH3 domain Sugar_tr PF00083.24 KXH55107.1 - 4.5e-90 302.7 25.5 5.4e-90 302.4 25.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH55107.1 - 4.3e-18 65.4 39.4 4e-15 55.6 7.5 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily DUF726 PF05277.12 KXH55109.1 - 9.4e-132 439.1 5.0 1.2e-131 438.7 5.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) DUF2951 PF11166.8 KXH55109.1 - 1.1 9.5 3.1 1e+02 3.2 4.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) Glu-tRNAGln PF02686.15 KXH55110.1 - 1e-11 44.9 0.0 3.9e-11 43.1 0.0 1.9 1 1 0 1 1 1 1 Glu-tRNAGln amidotransferase C subunit SNAP PF14938.6 KXH55111.1 - 3.5e-108 361.3 17.8 8.7e-94 314.1 9.8 2.0 2 0 0 2 2 2 2 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 KXH55111.1 - 2.6e-07 30.8 10.5 0.00036 20.8 0.1 4.1 3 1 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 KXH55111.1 - 5.6e-05 23.0 8.4 0.46 10.8 0.2 5.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 KXH55111.1 - 7.5e-05 22.5 11.9 0.57 10.4 0.1 6.4 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 KXH55111.1 - 0.00084 19.2 7.5 3.3 8.0 0.3 5.2 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 KXH55111.1 - 0.16 12.5 0.1 0.16 12.5 0.1 4.3 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.6 KXH55111.1 - 0.26 11.4 4.6 4.3 7.6 0.1 3.2 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 KXH55111.1 - 0.37 10.7 0.1 0.37 10.7 0.1 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 KXH55111.1 - 0.49 11.1 13.7 48 4.9 0.1 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_3 PF07720.12 KXH55111.1 - 0.94 9.5 6.9 2.6 8.1 0.5 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 KXH55111.1 - 1.1 10.0 0.0 1.1 10.0 0.0 4.7 4 2 1 5 5 5 0 Tetratricopeptide repeat DENN PF02141.21 KXH55112.1 - 1.3e-58 198.0 0.1 2.1e-58 197.3 0.1 1.3 1 0 0 1 1 1 1 DENN (AEX-3) domain dDENN PF03455.19 KXH55112.1 - 8.7e-16 57.6 1.3 2e-15 56.5 1.3 1.7 1 0 0 1 1 1 1 dDENN domain uDENN PF03456.18 KXH55112.1 - 2.1e-13 50.8 0.0 4.5e-13 49.7 0.0 1.6 1 0 0 1 1 1 1 uDENN domain C1_2 PF03107.16 KXH55112.1 - 0.0018 18.5 7.9 0.0035 17.6 7.9 1.4 1 0 0 1 1 1 1 C1 domain C1_1 PF00130.22 KXH55112.1 - 0.014 15.2 8.9 0.032 14.1 8.9 1.6 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Zf_RING PF16744.5 KXH55112.1 - 0.22 11.7 2.5 0.48 10.6 2.5 1.5 1 0 0 1 1 1 0 KIAA1045 RING finger PHD PF00628.29 KXH55112.1 - 0.37 10.7 6.8 0.86 9.5 6.8 1.7 1 0 0 1 1 1 0 PHD-finger zf-HIT PF04438.16 KXH55112.1 - 5.4 7.0 5.0 11 6.0 5.0 1.4 1 0 0 1 1 1 0 HIT zinc finger DUF974 PF06159.13 KXH55113.1 - 7.5e-80 268.3 0.0 9e-80 268.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF974) KH_1 PF00013.29 KXH55114.1 - 6.1e-09 35.6 0.0 1.7e-06 27.7 0.0 2.6 2 0 0 2 2 2 2 KH domain ALS_ss_C PF10369.9 KXH55115.1 - 1.7e-15 57.0 0.0 2.3e-14 53.3 0.0 2.5 2 1 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.25 KXH55115.1 - 7.1e-15 54.5 0.1 1.3e-14 53.6 0.1 1.5 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.6 KXH55115.1 - 1.3e-08 34.5 0.1 2.9e-08 33.4 0.0 1.6 2 0 0 2 2 2 1 ACT domain ACT_6 PF13740.6 KXH55115.1 - 0.11 12.5 0.0 26 4.9 0.0 2.6 2 0 0 2 2 2 0 ACT domain OTCace_N PF02729.21 KXH55116.1 - 4.9e-44 149.9 0.1 6.9e-44 149.4 0.1 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.24 KXH55116.1 - 2.6e-43 147.8 0.0 5.3e-43 146.8 0.0 1.5 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain DUF3712 PF12505.8 KXH55117.1 - 1.6e-08 34.9 0.0 2.7e-06 27.7 0.1 2.9 2 0 0 2 2 2 2 Protein of unknown function (DUF3712) PEHE PF15275.6 KXH55119.1 - 0.25 12.0 6.4 0.15 12.7 2.3 2.1 1 1 0 2 2 2 0 PEHE domain SART-1 PF03343.13 KXH55120.1 - 2e-184 614.7 68.2 2.3e-184 614.5 68.2 1.0 1 0 0 1 1 1 1 SART-1 family Glyco_hydro_15 PF00723.21 KXH55121.1 - 6.2e-104 348.3 0.0 7.3e-104 348.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.19 KXH55121.1 - 6.4e-35 119.0 0.4 1.3e-34 117.9 0.4 1.6 1 0 0 1 1 1 1 Starch binding domain CPT PF07931.12 KXH55122.1 - 5.5e-05 23.1 0.0 0.0001 22.2 0.0 1.4 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_18 PF13238.6 KXH55122.1 - 0.0018 18.9 0.0 0.0037 17.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KXH55122.1 - 0.039 14.2 0.0 0.063 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain PRK PF00485.18 KXH55122.1 - 0.039 13.7 0.0 0.063 13.0 0.0 1.7 1 1 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family CoaE PF01121.20 KXH55122.1 - 0.11 12.1 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Dephospho-CoA kinase PTH2 PF01981.16 KXH55123.1 - 8.8e-40 135.6 0.8 3.3e-35 120.9 0.1 2.2 2 0 0 2 2 2 2 Peptidyl-tRNA hydrolase PTH2 BING4CT PF08149.11 KXH55124.1 - 1.5e-36 124.0 0.0 2.5e-33 113.7 0.0 3.6 3 0 0 3 3 3 1 BING4CT (NUC141) domain Coatomer_WDAD PF04053.14 KXH55124.1 - 1.9e-05 23.9 0.2 6.9e-05 22.1 0.0 1.8 2 0 0 2 2 2 1 Coatomer WD associated region ANAPC4_WD40 PF12894.7 KXH55124.1 - 2.1e-05 24.7 0.1 3.7 7.9 0.0 5.7 3 1 4 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KXH55124.1 - 2.8e-05 24.8 0.1 0.038 14.9 0.0 4.1 5 0 0 5 5 5 1 WD domain, G-beta repeat RIBIOP_C PF04950.12 KXH55125.1 - 3e-109 365.0 0.0 4.2e-109 364.5 0.0 1.2 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 KXH55125.1 - 6.7e-18 64.6 0.0 1.5e-17 63.4 0.0 1.7 1 0 0 1 1 1 1 AARP2CN (NUC121) domain cobW PF02492.19 KXH55126.1 - 4.6e-34 117.5 0.0 5.9e-34 117.2 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 KXH55126.1 - 0.00015 20.8 0.6 0.0012 17.9 0.6 1.9 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_23 PF13476.6 KXH55126.1 - 0.0028 18.2 0.0 0.0038 17.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 KXH55126.1 - 0.0034 17.4 0.0 0.013 15.6 0.0 2.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase ResIII PF04851.15 KXH55126.1 - 0.082 12.9 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_11 PF13086.6 KXH55126.1 - 0.1 12.3 0.0 14 5.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KXH55126.1 - 0.12 12.8 0.0 0.16 12.3 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 KXH55126.1 - 0.2 11.5 0.0 0.3 11.0 0.0 1.3 1 0 0 1 1 1 0 NACHT domain PPI_Ypi1 PF07491.11 KXH55127.1 - 4.7e-25 87.2 2.6 1.7e-24 85.4 2.6 2.0 1 1 0 1 1 1 1 Protein phosphatase inhibitor CDC45 PF02724.14 KXH55127.1 - 1.3 7.3 5.5 1.4 7.1 5.5 1.1 1 0 0 1 1 1 0 CDC45-like protein MMR_HSR1 PF01926.23 KXH55128.1 - 0.0002 21.4 0.0 1.3 9.1 0.0 2.9 3 0 0 3 3 3 2 50S ribosome-binding GTPase Trypan_PARP PF05887.11 KXH55128.1 - 0.0098 15.9 3.6 0.023 14.7 3.6 1.6 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) SPESP1 PF15754.5 KXH55128.1 - 0.21 10.7 1.2 0.38 9.9 1.2 1.3 1 0 0 1 1 1 0 Sperm equatorial segment protein 1 L51_S25_CI-B8 PF05047.16 KXH55129.1 - 5.1e-13 48.7 0.1 8.2e-13 48.1 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain HECT PF00632.25 KXH55130.1 - 1e-76 258.4 0.0 1.4e-76 258.0 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF3712 PF12505.8 KXH55131.1 - 1.6e-12 47.8 0.0 4.4e-12 46.4 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3712) ADH_N PF08240.12 KXH55132.1 - 1.6e-25 89.1 2.2 3.5e-25 88.0 0.9 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXH55132.1 - 1.1e-14 54.5 0.0 1.8e-14 53.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KXH55132.1 - 8.1e-11 41.8 0.0 1.2e-10 41.2 0.0 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KXH55132.1 - 8e-09 36.6 0.0 1.4e-08 35.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FAD_binding_3 PF01494.19 KXH55132.1 - 0.023 14.0 0.1 0.036 13.3 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain fn3 PF00041.21 KXH55132.1 - 0.05 14.0 0.0 6.5 7.2 0.0 2.4 2 0 0 2 2 2 0 Fibronectin type III domain Staph_opine_DH PF10100.9 KXH55132.1 - 0.18 10.4 0.0 0.24 10.0 0.0 1.2 1 0 0 1 1 1 0 Staphylopine dehydrogenase S10_plectin PF03501.15 KXH55133.1 - 1.6e-42 143.4 0.1 2e-42 143.2 0.1 1.1 1 0 0 1 1 1 1 Plectin/S10 domain Sde2_N_Ubi PF13019.6 KXH55134.1 - 4.3e-70 234.8 0.8 6.3e-70 234.3 0.8 1.2 1 0 0 1 1 1 1 Silencing defective 2 N-terminal ubiquitin domain COX6B PF02297.17 KXH55135.1 - 6.2e-18 64.8 4.4 7e-18 64.6 4.4 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb CX9C PF16860.5 KXH55135.1 - 0.017 15.1 2.4 0.026 14.5 2.4 1.3 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, APOBEC_C PF05240.14 KXH55135.1 - 0.12 12.3 2.3 0.13 12.2 1.4 1.5 1 1 0 1 1 1 0 APOBEC-like C-terminal domain B12D PF06522.11 KXH55136.1 - 5.9e-06 26.0 0.0 7.8e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit RRM_1 PF00076.22 KXH55137.1 - 6.6e-18 64.3 0.0 9.6e-18 63.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KXH55137.1 - 1.3e-05 25.2 0.0 1.8e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif Nup35_RRM_2 PF14605.6 KXH55137.1 - 0.042 13.9 0.0 0.069 13.2 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 KXH55137.1 - 0.077 12.6 0.0 0.16 11.6 0.0 1.4 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 KXH55137.1 - 0.13 12.4 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 Limkain b1 RRM_occluded PF16842.5 KXH55137.1 - 0.15 11.9 0.0 0.45 10.4 0.0 1.9 1 1 0 1 1 1 0 Occluded RNA-recognition motif Sec16_C PF12931.7 KXH55138.1 - 1.8e-11 44.3 0.8 4.8e-10 39.6 0.8 2.4 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 SRA1 PF07304.11 KXH55138.1 - 8.5e-11 41.8 0.0 8.5e-11 41.8 0.0 4.3 3 1 1 4 4 4 1 Steroid receptor RNA activator (SRA1) WD40 PF00400.32 KXH55138.1 - 7e-05 23.5 4.6 0.017 16.0 0.0 4.9 6 0 0 6 6 6 1 WD domain, G-beta repeat Prp18 PF02840.15 KXH55138.1 - 0.018 15.1 0.2 0.05 13.6 0.2 1.8 1 1 0 1 1 1 0 Prp18 domain PALB2_WD40 PF16756.5 KXH55138.1 - 0.036 13.0 0.0 0.23 10.4 0.0 1.9 1 1 1 2 2 2 0 Partner and localizer of BRCA2 WD40 domain GET2 PF08690.10 KXH55139.1 - 1.2e-45 156.5 0.0 1.6e-45 156.2 0.0 1.1 1 0 0 1 1 1 1 GET complex subunit GET2 p450 PF00067.22 KXH55140.1 - 1.6e-40 139.3 0.1 2.3e-25 89.3 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 HLH PF00010.26 KXH55141.1 - 1.7e-07 31.1 0.0 3.6e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain IR1-M PF12185.8 KXH55141.1 - 0.048 13.6 1.2 1.3 9.0 0.0 2.8 2 0 0 2 2 2 0 Nup358/RanBP2 E3 ligase domain DUF4407 PF14362.6 KXH55141.1 - 0.7 9.2 2.7 1 8.7 2.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CDC45 PF02724.14 KXH55141.1 - 7.5 4.7 10.0 12 4.1 10.0 1.2 1 0 0 1 1 1 0 CDC45-like protein TMEM135_C_rich PF15982.5 KXH55142.1 - 0.014 16.0 0.6 0.074 13.6 0.6 2.2 1 1 0 1 1 1 0 N-terminal cysteine-rich region of Transmembrane protein 135 DJ-1_PfpI PF01965.24 KXH55143.1 - 5.9e-20 71.7 0.0 8.3e-20 71.2 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family GATase PF00117.28 KXH55143.1 - 0.036 13.8 0.0 0.044 13.5 0.0 1.2 1 0 0 1 1 1 0 Glutamine amidotransferase class-I Gp_dh_C PF02800.20 KXH55145.1 - 4e-71 237.7 0.1 6.3e-71 237.1 0.1 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 KXH55145.1 - 6.3e-40 135.6 0.1 1.4e-39 134.5 0.1 1.6 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 KXH55145.1 - 0.0027 17.8 0.2 0.012 15.7 0.2 2.2 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus ADH_zinc_N PF00107.26 KXH55145.1 - 0.036 14.0 0.1 0.078 13.0 0.1 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KXH55145.1 - 0.11 11.8 0.2 0.35 10.2 0.0 1.8 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CENP-F_leu_zip PF10473.9 KXH55147.1 - 7.4e-05 22.8 42.9 0.26 11.3 3.6 6.0 3 2 2 5 5 5 4 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.6 KXH55147.1 - 0.0015 17.9 6.1 0.0015 17.9 6.1 5.7 5 1 0 5 5 5 2 Growth-arrest specific micro-tubule binding bZIP_1 PF00170.21 KXH55147.1 - 0.022 14.9 20.5 3.4 7.8 6.2 5.9 2 2 3 5 5 5 0 bZIP transcription factor Spc7 PF08317.11 KXH55147.1 - 0.022 13.7 60.8 0.015 14.2 1.6 5.5 2 2 1 5 5 5 0 Spc7 kinetochore protein DUF1664 PF07889.12 KXH55147.1 - 0.082 13.0 36.8 0.74 9.9 2.1 6.5 3 2 3 6 6 6 0 Protein of unknown function (DUF1664) EzrA PF06160.12 KXH55147.1 - 0.54 8.4 41.0 0.0043 15.3 4.7 4.7 4 1 1 5 5 5 0 Septation ring formation regulator, EzrA Baculo_PEP_C PF04513.12 KXH55147.1 - 2.2 8.3 33.5 0.8 9.7 1.7 6.3 4 2 1 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus Osmo_CC PF08946.10 KXH55147.1 - 2.6 8.4 7.8 9 6.6 0.1 4.8 5 0 0 5 5 5 0 Osmosensory transporter coiled coil Fib_alpha PF08702.10 KXH55147.1 - 8 6.6 55.1 0.017 15.3 5.8 6.9 3 2 5 8 8 8 0 Fibrinogen alpha/beta chain family Taxilin PF09728.9 KXH55147.1 - 8.2 5.5 41.1 0.053 12.7 4.9 4.7 4 1 0 4 4 4 0 Myosin-like coiled-coil protein TIP49 PF06068.13 KXH55148.1 - 5.3e-154 512.6 1.6 6.8e-154 512.3 1.6 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 KXH55148.1 - 9.8e-21 73.7 0.9 3.4e-20 71.9 0.6 2.2 2 0 0 2 2 2 1 TIP49 AAA-lid domain RuvB_N PF05496.12 KXH55148.1 - 3.4e-09 36.6 0.5 3.2e-05 23.7 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA PF00004.29 KXH55148.1 - 2.2e-08 34.6 0.5 5e-05 23.7 0.0 3.2 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) DnaB_C PF03796.15 KXH55148.1 - 3.4e-06 26.6 0.9 7.1e-06 25.5 0.9 1.5 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_16 PF13191.6 KXH55148.1 - 2.6e-05 24.7 0.1 7.4e-05 23.2 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.21 KXH55148.1 - 0.00099 18.5 0.8 0.021 14.2 0.3 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 KXH55148.1 - 0.0057 16.4 0.0 2.2 8.0 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_19 PF13245.6 KXH55148.1 - 0.008 16.5 2.0 0.59 10.5 2.0 2.7 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KXH55148.1 - 0.0099 16.2 0.0 0.7 10.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 KXH55148.1 - 0.016 15.0 0.9 0.11 12.3 0.1 2.1 1 1 1 2 2 2 0 AAA domain AAA_5 PF07728.14 KXH55148.1 - 0.02 14.9 0.1 3.5 7.6 0.0 2.9 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Parvo_NS1 PF01057.17 KXH55148.1 - 0.033 13.3 0.0 0.063 12.4 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_25 PF13481.6 KXH55148.1 - 0.047 13.3 0.1 0.092 12.3 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KXH55148.1 - 0.057 13.6 0.0 0.47 10.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KXH55148.1 - 0.1 12.1 0.1 0.43 10.1 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_28 PF13521.6 KXH55148.1 - 0.13 12.5 0.0 0.29 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain GYF PF02213.16 KXH55149.1 - 8.4e-12 44.6 2.5 2.7e-11 42.9 2.5 1.9 1 0 0 1 1 1 1 GYF domain GYF_2 PF14237.6 KXH55149.1 - 0.0096 15.7 0.2 0.024 14.4 0.2 1.7 1 0 0 1 1 1 1 GYF domain 2 HTH_WhiA PF02650.14 KXH55149.1 - 0.088 13.1 1.4 0.2 12.0 1.4 1.5 1 0 0 1 1 1 0 WhiA C-terminal HTH domain UFD1 PF03152.14 KXH55150.1 - 7e-69 230.7 0.0 8.7e-69 230.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 ORC6 PF05460.13 KXH55154.1 - 0.018 14.3 7.7 0.025 13.9 7.7 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) U79_P34 PF03064.16 KXH55154.1 - 0.024 14.0 1.6 0.03 13.7 1.6 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Pox_Ag35 PF03286.14 KXH55154.1 - 1 9.1 12.1 1.9 8.3 12.1 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein HSP90 PF00183.18 KXH55165.1 - 2.8e-222 739.2 29.9 3.6e-222 738.9 29.9 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 KXH55165.1 - 6.1e-15 55.7 0.1 1.1e-14 54.8 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KXH55165.1 - 1.5e-09 37.8 0.1 4.7e-09 36.2 0.1 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase LOH1CR12 PF10158.9 KXH55165.1 - 0.034 14.2 0.3 0.13 12.3 0.3 2.0 1 0 0 1 1 1 0 Tumour suppressor protein Cofac_haem_bdg PF04187.13 KXH55165.1 - 0.14 12.1 0.4 0.56 10.2 0.1 2.1 2 0 0 2 2 2 0 Haem-binding uptake, Tiki superfamily, ChaN Bac_rhamnosid6H PF17389.2 KXH55166.1 - 5.4e-10 39.0 0.1 9.8e-10 38.2 0.1 1.3 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Trehalase PF01204.18 KXH55166.1 - 0.0074 15.2 0.2 0.011 14.6 0.2 1.1 1 0 0 1 1 1 1 Trehalase Syntaxin-18_N PF10496.9 KXH55176.1 - 0.01 16.1 0.5 0.063 13.5 0.1 2.7 2 1 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus Fungal_trans_2 PF11951.8 KXH55176.1 - 0.045 12.6 0.4 0.093 11.5 0.2 1.6 1 1 0 1 1 1 0 Fungal specific transcription factor domain SNARE PF05739.19 KXH55176.1 - 0.13 12.3 0.0 0.37 10.8 0.0 1.8 1 0 0 1 1 1 0 SNARE domain DUF5365 PF17326.2 KXH55176.1 - 0.3 11.5 1.1 4.3 7.8 0.0 2.7 3 0 0 3 3 3 0 Family of unknown function (DUF5365) Mrr_N PF14338.6 KXH55176.1 - 0.82 9.8 3.2 0.77 9.9 0.2 2.4 3 0 0 3 3 3 0 Mrr N-terminal domain MFS_1 PF07690.16 KXH55177.1 - 2.4e-47 161.6 17.4 2.4e-47 161.6 17.4 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH55177.1 - 2.7e-09 36.4 2.1 2.7e-09 36.4 2.1 2.5 3 0 0 3 3 3 2 Sugar (and other) transporter OATP PF03137.20 KXH55177.1 - 0.085 11.1 1.1 0.17 10.2 1.1 1.5 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family MFS_3 PF05977.13 KXH55177.1 - 0.59 8.5 17.0 0.0074 14.7 7.4 2.3 3 0 0 3 3 3 0 Transmembrane secretion effector DUF1077 PF06417.12 KXH55179.1 - 5e-50 168.4 6.1 7.4e-50 167.9 6.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) Adaptin_N PF01602.20 KXH55180.1 - 3.3e-120 402.1 10.3 4.2e-120 401.8 10.3 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KXH55180.1 - 2e-55 187.3 0.2 2e-55 187.3 0.2 3.3 3 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KXH55180.1 - 2.4e-15 56.7 5.6 5.3e-05 23.5 0.1 4.9 4 1 1 5 5 5 4 HEAT repeats HEAT PF02985.22 KXH55180.1 - 2e-10 40.0 4.3 0.00065 19.8 0.0 5.5 6 0 0 6 6 6 3 HEAT repeat CLASP_N PF12348.8 KXH55180.1 - 0.00015 21.4 0.2 0.045 13.3 0.0 2.7 2 0 0 2 2 2 2 CLASP N terminal HEAT_EZ PF13513.6 KXH55180.1 - 0.0021 18.6 5.1 22 5.7 0.0 6.0 6 0 0 6 6 6 0 HEAT-like repeat Atx10homo_assoc PF09759.9 KXH55180.1 - 0.0024 17.9 0.2 19 5.4 0.0 4.8 5 1 0 5 5 5 1 Spinocerebellar ataxia type 10 protein domain RTP1_C1 PF10363.9 KXH55180.1 - 0.0045 17.1 1.3 0.61 10.3 0.0 3.5 2 1 1 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 Arm PF00514.23 KXH55180.1 - 0.54 10.4 3.4 9.6 6.4 0.1 4.2 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Rad60-SLD_2 PF13881.6 KXH55181.1 - 6.1e-12 45.6 0.0 1.2e-11 44.7 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KXH55181.1 - 0.00014 21.5 0.0 0.00027 20.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 KXH55181.1 - 0.0029 18.1 0.0 0.0073 16.9 0.0 1.6 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain UMP1 PF05348.11 KXH55182.1 - 3.2e-44 150.0 0.1 4.1e-44 149.6 0.1 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 ABC_tran PF00005.27 KXH55183.1 - 4.1e-22 79.2 0.0 6.3e-10 39.7 0.0 3.8 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KXH55183.1 - 7.1e-08 32.6 1.1 0.14 11.9 0.3 3.4 2 1 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 KXH55183.1 - 2.3e-06 27.7 0.2 0.0022 18.2 0.2 2.5 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 KXH55183.1 - 8.4e-05 23.2 0.4 0.33 11.4 0.1 2.2 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 KXH55183.1 - 0.00013 22.2 0.0 1.1 9.5 0.0 3.0 4 0 0 4 4 3 2 AAA domain AAA_29 PF13555.6 KXH55183.1 - 0.00045 19.9 0.1 0.58 9.9 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_24 PF13479.6 KXH55183.1 - 0.0091 15.7 0.0 3.6 7.2 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KXH55183.1 - 0.013 16.0 0.0 6.1 7.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KXH55183.1 - 0.014 15.5 0.0 1.4 9.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KXH55183.1 - 0.033 14.6 0.0 4.5 7.6 0.0 2.5 2 1 0 2 2 2 0 AAA ATPase domain AAA_28 PF13521.6 KXH55183.1 - 0.035 14.3 0.0 10 6.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain Ploopntkinase1 PF18748.1 KXH55183.1 - 0.043 13.3 0.0 0.075 12.5 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase1 RNA_helicase PF00910.22 KXH55183.1 - 0.055 13.9 0.0 2.3 8.6 0.0 2.4 2 0 0 2 2 2 0 RNA helicase AAA PF00004.29 KXH55183.1 - 0.062 13.7 0.1 1.6 9.2 0.0 3.0 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.9 KXH55183.1 - 0.08 12.7 0.0 0.63 9.8 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 KXH55183.1 - 0.12 11.8 0.0 3.6 7.0 0.0 2.2 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit TniB PF05621.11 KXH55183.1 - 0.14 11.6 0.0 11 5.3 0.0 2.2 2 0 0 2 2 2 0 Bacterial TniB protein AAA_14 PF13173.6 KXH55183.1 - 0.19 11.8 0.0 9.7 6.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 KXH55183.1 - 0.23 11.0 0.0 5.4 6.6 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ATPase_2 PF01637.18 KXH55183.1 - 0.26 11.2 0.0 19 5.0 0.0 2.2 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Chitin_synth_1 PF01644.17 KXH55184.1 - 1.9e-76 255.6 0.0 3.2e-76 254.8 0.0 1.4 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 KXH55184.1 - 9.7e-28 95.9 0.2 2.4e-27 94.7 0.2 1.7 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 KXH55184.1 - 4.5e-22 78.4 2.1 4.7e-19 68.4 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 KXH55184.1 - 9.3e-09 35.5 0.2 9.3e-09 35.5 0.2 2.2 3 1 0 3 3 3 1 Glycosyl transferase family group 2 Tyrosinase PF00264.20 KXH55185.1 - 2e-46 159.1 1.6 3.3e-46 158.3 1.6 1.4 1 0 0 1 1 1 1 Common central domain of tyrosinase Tyosinase_C PF18132.1 KXH55185.1 - 1.9e-33 115.7 0.0 3e-33 115.1 0.0 1.3 1 0 0 1 1 1 1 Tyosinase C-terminal domain Tannase PF07519.11 KXH55186.1 - 1.7e-146 488.8 8.5 2e-146 488.6 8.5 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Asparaginase_2 PF01112.18 KXH55187.1 - 2e-71 240.6 7.6 2.5e-71 240.2 7.6 1.0 1 0 0 1 1 1 1 Asparaginase Aminotran_3 PF00202.21 KXH55188.1 - 7e-47 160.0 0.0 2.8e-25 88.8 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-III MFS_1 PF07690.16 KXH55189.1 - 5.5e-45 153.8 30.3 5.5e-45 153.8 30.3 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH55189.1 - 3.1e-12 46.1 12.1 3.1e-12 46.1 12.1 2.2 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 KXH55189.1 - 1.2e-05 24.0 6.2 2e-05 23.2 6.2 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.7 KXH55189.1 - 0.5 9.2 12.4 0.23 10.3 6.0 2.6 2 1 0 2 2 2 0 MFS_1 like family MFS_3 PF05977.13 KXH55189.1 - 5.4 5.3 16.3 0.15 10.4 7.4 2.1 2 0 0 2 2 2 0 Transmembrane secretion effector OATP PF03137.20 KXH55189.1 - 9.3 4.4 10.9 2 6.6 1.9 2.9 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family PTP_tm PF18861.1 KXH55190.1 - 0.068 13.2 0.4 0.11 12.4 0.4 1.3 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J SnoaL_3 PF13474.6 KXH55192.1 - 8.8e-05 22.8 0.2 0.00011 22.5 0.2 1.0 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 KXH55192.1 - 0.0019 18.6 0.1 0.0024 18.3 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) Imm-NTF2 PF15655.6 KXH55192.1 - 0.01 16.1 0.0 0.012 15.9 0.0 1.1 1 0 0 1 1 1 0 NTF2 fold immunity protein DUF3828 PF12883.7 KXH55192.1 - 0.039 14.3 0.0 0.052 13.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3828) Kunitz_legume PF00197.18 KXH55192.1 - 0.046 13.7 0.0 0.053 13.5 0.0 1.1 1 0 0 1 1 1 0 Trypsin and protease inhibitor SnoaL_2 PF12680.7 KXH55192.1 - 0.048 14.3 0.0 0.055 14.1 0.0 1.1 1 0 0 1 1 1 0 SnoaL-like domain DUF3804 PF12707.7 KXH55192.1 - 0.089 12.5 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3804) SnoaL_4 PF13577.6 KXH55192.1 - 0.12 12.5 0.2 0.18 11.9 0.2 1.3 1 1 0 1 1 1 0 SnoaL-like domain DUF2793 PF10983.8 KXH55192.1 - 0.14 12.1 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2793) peroxidase PF00141.23 KXH55193.1 - 9e-85 284.0 0.0 6.1e-46 157.0 0.0 2.3 2 0 0 2 2 2 2 Peroxidase GST_C_3 PF14497.6 KXH55193.1 - 0.031 14.5 0.0 10 6.4 0.0 2.6 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain F-box-like PF12937.7 KXH55194.1 - 0.012 15.4 0.0 0.025 14.5 0.0 1.5 1 0 0 1 1 1 0 F-box-like DUF3827 PF12877.7 KXH55194.1 - 0.066 11.6 0.5 0.081 11.3 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) zf-C3HC4_2 PF13923.6 KXH55194.1 - 0.068 13.0 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF515 PF04415.12 KXH55194.1 - 0.84 8.0 4.6 43 2.3 6.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF515) PAF-AH_p_II PF03403.13 KXH55196.1 - 8.1e-21 74.0 0.0 2.8e-09 36.0 0.0 2.1 1 1 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 KXH55196.1 - 5.2e-08 32.1 0.0 1.8e-07 30.3 0.0 1.9 1 1 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 KXH55196.1 - 0.00037 19.6 0.0 0.0058 15.7 0.0 2.1 2 0 0 2 2 2 1 Chlorophyllase Hydrolase_4 PF12146.8 KXH55196.1 - 0.00069 18.9 0.3 0.87 8.8 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KXH55196.1 - 0.018 15.7 0.2 0.035 14.7 0.2 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 KXH55196.1 - 0.018 14.8 0.0 1.6 8.5 0.0 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KXH55196.1 - 0.078 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Acetyltransf_10 PF13673.7 KXH55197.1 - 1.1e-07 31.8 0.0 1.5e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXH55197.1 - 1.7e-05 25.2 0.0 2.3e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXH55197.1 - 0.00048 20.4 0.0 0.00061 20.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 KXH55197.1 - 0.0027 17.8 0.9 0.016 15.3 0.9 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain NodA PF02474.15 KXH55197.1 - 0.1 12.3 0.0 0.12 12.0 0.0 1.1 1 0 0 1 1 1 0 Nodulation protein A (NodA) Cutinase PF01083.22 KXH55198.1 - 2.8e-29 102.3 0.6 5.1e-29 101.5 0.6 1.4 1 0 0 1 1 1 1 Cutinase Sporozoite_P67 PF05642.11 KXH55198.1 - 0.059 11.5 6.4 0.06 11.4 6.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Peptidase_M28 PF04389.17 KXH55199.1 - 6.6e-37 127.1 0.0 1.1e-36 126.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KXH55199.1 - 1.1e-10 41.4 1.5 2.4e-10 40.3 1.5 1.6 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 KXH55199.1 - 3.5e-05 23.6 0.0 9.2e-05 22.2 0.0 1.7 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Ribosomal_L36e PF01158.18 KXH55202.1 - 0.12 12.7 2.9 0.14 12.4 1.4 1.9 2 0 0 2 2 2 0 Ribosomal protein L36e DEAD PF00270.29 KXH55203.1 - 2.2e-44 151.3 0.1 4.1e-44 150.4 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXH55203.1 - 7.1e-18 65.0 0.0 2e-17 63.5 0.0 1.9 1 1 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KXH55203.1 - 2.9e-15 56.2 0.2 5.9e-15 55.2 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KXH55203.1 - 1.1e-06 28.8 0.0 2.3e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit IBR PF01485.21 KXH55204.1 - 2.6e-11 43.6 16.4 4.6e-09 36.4 4.3 3.6 3 0 0 3 3 3 3 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 KXH55204.1 - 0.0011 18.8 4.6 0.0011 18.8 4.6 2.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXH55204.1 - 0.0048 16.7 3.2 0.0048 16.7 3.2 3.1 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXH55204.1 - 0.005 16.8 8.1 0.005 16.8 8.1 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 KXH55204.1 - 0.015 15.3 7.5 0.015 15.3 7.5 2.9 3 0 0 3 3 3 0 zinc-RING finger domain zf-RING_2 PF13639.6 KXH55204.1 - 0.02 15.2 6.7 0.02 15.2 6.7 3.2 2 1 1 3 3 3 0 Ring finger domain CsiV PF10972.8 KXH55204.1 - 0.18 11.5 0.5 0.22 11.2 0.5 1.2 1 0 0 1 1 1 0 Peptidoglycan-binding protein, CsiV Prok-RING_4 PF14447.6 KXH55204.1 - 8.3 6.4 15.3 3.4 7.6 5.2 3.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 adh_short PF00106.25 KXH55386.1 - 5.5e-44 150.0 0.3 7e-44 149.6 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXH55386.1 - 2.9e-40 138.3 0.7 2.7e-39 135.1 0.7 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KXH55386.1 - 0.0056 16.2 0.1 0.017 14.6 0.0 1.7 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KXH55386.1 - 0.011 15.7 0.3 0.026 14.5 0.3 1.5 1 1 0 1 1 1 0 KR domain DCP2 PF05026.13 KXH55387.1 - 5.1e-31 106.8 0.5 8.7e-31 106.1 0.5 1.4 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.28 KXH55387.1 - 1.7e-15 57.2 0.1 3.1e-15 56.4 0.1 1.4 1 0 0 1 1 1 1 NUDIX domain DUF4112 PF13430.6 KXH55388.1 - 4.1e-36 123.4 0.3 5.3e-36 123.1 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) AgrD PF05931.11 KXH55388.1 - 0.11 12.5 0.3 0.18 11.9 0.3 1.3 1 0 0 1 1 1 0 Staphylococcal AgrD protein Ribonuc_red_sm PF00268.21 KXH55390.1 - 4.6e-121 403.6 2.2 5.8e-121 403.2 2.2 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain SRP9-21 PF05486.12 KXH55391.1 - 2.4e-19 69.5 0.0 4.6e-19 68.6 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) WD40 PF00400.32 KXH55392.1 - 9.8e-16 57.9 3.9 3.2e-07 30.9 0.1 6.4 6 1 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXH55392.1 - 3.4e-05 24.1 0.0 0.59 10.5 0.0 4.4 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Mito_carr PF00153.27 KXH55393.1 - 1.8e-42 143.2 0.9 7.8e-16 57.8 0.4 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Suv3_N PF18114.1 KXH55393.1 - 0.054 13.6 0.0 0.36 11.0 0.0 2.0 2 0 0 2 2 2 0 Suv3 helical N-terminal domain CTU2 PF10288.9 KXH55394.1 - 2.2e-13 50.4 0.1 2e-11 44.1 0.1 2.6 1 1 0 1 1 1 1 Cytoplasmic tRNA 2-thiolation protein 2 DZR PF12773.7 KXH55394.1 - 0.48 10.5 4.6 6.2 6.9 0.1 2.4 2 0 0 2 2 2 0 Double zinc ribbon zf-FPG_IleRS PF06827.14 KXH55394.1 - 3.1 7.8 7.9 5.4 7.0 5.6 2.5 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS APH PF01636.23 KXH55395.1 - 4.5e-07 30.0 0.0 5.5e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KXH55395.1 - 1.3e-06 28.2 0.1 2.1e-06 27.5 0.1 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.20 KXH55395.1 - 1.8e-05 24.2 0.1 3e-05 23.5 0.1 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase Fructosamin_kin PF03881.14 KXH55395.1 - 0.042 13.1 0.0 0.066 12.4 0.0 1.4 1 0 0 1 1 1 0 Fructosamine kinase PH PF00169.29 KXH55396.1 - 2.5e-27 95.4 1.6 3.3e-16 59.7 0.2 2.2 2 0 0 2 2 2 2 PH domain PH_11 PF15413.6 KXH55396.1 - 2.6e-09 37.5 5.3 0.00018 21.9 0.8 3.1 2 1 0 2 2 2 2 Pleckstrin homology domain PH_9 PF15410.6 KXH55396.1 - 7.6e-08 32.7 2.1 3.2e-05 24.3 0.5 3.5 2 2 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.6 KXH55396.1 - 9.8e-06 25.8 0.2 2e-05 24.8 0.2 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.6 KXH55396.1 - 0.0065 16.6 0.6 0.027 14.6 0.3 2.2 2 1 0 2 2 2 1 PH domain Cellulase PF00150.18 KXH55397.1 - 2.1e-19 70.0 0.6 3.6e-19 69.3 0.6 1.3 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) efThoc1 PF11957.8 KXH55398.1 - 4.9e-143 477.4 7.1 4.9e-143 477.4 7.1 1.6 2 0 0 2 2 2 1 THO complex subunit 1 transcription elongation factor Guanylate_kin PF00625.21 KXH55398.1 - 4e-26 91.8 0.0 9.4e-26 90.6 0.0 1.6 1 0 0 1 1 1 1 Guanylate kinase AAA_28 PF13521.6 KXH55398.1 - 0.008 16.4 0.7 0.019 15.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KXH55398.1 - 0.011 15.8 0.0 0.075 13.2 0.0 2.3 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KXH55398.1 - 0.022 15.1 0.4 10 6.6 0.0 3.2 3 0 0 3 3 3 0 RNA helicase AAA_18 PF13238.6 KXH55398.1 - 0.034 14.7 0.1 0.18 12.4 0.0 2.4 2 1 1 3 3 3 0 AAA domain MMR_HSR1 PF01926.23 KXH55398.1 - 0.036 14.2 0.0 0.13 12.4 0.0 2.0 1 0 0 1 1 1 0 50S ribosome-binding GTPase Aquarius_N PF16399.5 KXH55399.1 - 0 1112.1 0.0 0 1111.8 0.0 1.1 1 0 0 1 1 1 1 Intron-binding protein aquarius N-terminus AAA_12 PF13087.6 KXH55399.1 - 1.8e-26 93.0 0.0 3.4e-26 92.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KXH55399.1 - 4.5e-20 72.5 0.7 1.6e-19 70.8 0.0 2.3 2 1 0 2 2 1 1 AAA domain AAA_30 PF13604.6 KXH55399.1 - 1.4e-07 31.4 0.0 0.00021 21.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain ResIII PF04851.15 KXH55399.1 - 6e-06 26.4 0.0 1.5e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KXH55399.1 - 1e-05 25.9 0.0 2.3e-05 24.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KXH55399.1 - 0.00067 20.1 0.7 0.01 16.2 0.0 3.3 2 1 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 KXH55399.1 - 0.0017 18.8 0.0 0.0063 16.9 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DnaB_C PF03796.15 KXH55399.1 - 0.0041 16.5 0.0 0.0088 15.4 0.0 1.5 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain Viral_helicase1 PF01443.18 KXH55399.1 - 0.0049 16.6 0.2 0.38 10.5 0.0 3.2 4 0 0 4 4 4 1 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 KXH55399.1 - 0.033 14.4 0.0 0.14 12.4 0.0 2.1 1 0 0 1 1 1 0 AAA domain DEAD PF00270.29 KXH55399.1 - 0.04 13.7 0.0 0.086 12.6 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase UvrD-helicase PF00580.21 KXH55399.1 - 0.072 12.6 0.3 0.38 10.2 0.0 2.3 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain DUF2075 PF09848.9 KXH55399.1 - 0.14 11.4 0.9 0.2 10.9 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Cation_efflux PF01545.21 KXH55519.1 - 1.2e-12 48.0 12.1 1.7e-12 47.5 12.1 1.1 1 0 0 1 1 1 1 Cation efflux family Oleosin PF01277.17 KXH55519.1 - 0.31 10.8 3.8 0.68 9.7 0.9 2.6 3 0 0 3 3 3 0 Oleosin Dynamin_N PF00350.23 KXH55520.1 - 1.5e-43 148.8 0.0 2.8e-43 147.9 0.0 1.5 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 KXH55520.1 - 4.3e-12 45.9 0.1 1.7e-09 37.4 0.0 2.3 2 0 0 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.23 KXH55520.1 - 9.3e-06 25.7 0.0 0.00013 22.0 0.0 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF4872 PF16169.5 KXH55520.1 - 0.0051 16.6 1.7 0.017 14.9 0.7 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4872) AAA_16 PF13191.6 KXH55520.1 - 0.023 15.1 3.6 0.069 13.5 0.0 2.9 3 1 0 3 3 3 0 AAA ATPase domain AAA_21 PF13304.6 KXH55520.1 - 0.045 13.5 0.0 0.086 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Roc PF08477.13 KXH55520.1 - 0.064 13.5 0.3 0.45 10.7 0.0 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_28 PF13521.6 KXH55520.1 - 0.079 13.2 0.0 0.22 11.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 KXH55520.1 - 0.095 12.4 0.1 0.24 11.1 0.1 1.6 1 0 0 1 1 1 0 AAA ATPase domain GATase_4 PF13230.6 KXH55521.1 - 3.8e-16 58.8 0.0 4.8e-14 51.9 0.0 2.2 1 1 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.6 KXH55521.1 - 3.8e-08 33.6 0.0 1.1e-07 32.1 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase domain DUF2560 PF10834.8 KXH55522.1 - 0.31 11.3 1.1 0.4 10.9 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2560) PQ-loop PF04193.14 KXH55523.1 - 8.5e-33 111.9 9.1 7.2e-17 60.9 0.5 2.4 2 0 0 2 2 2 2 PQ loop repeat Mito_carr PF00153.27 KXH55524.1 - 1.7e-72 239.4 0.3 3.5e-25 87.8 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.32 KXH55524.1 - 1.4e-17 61.8 7.3 1e-07 31.0 0.5 5.2 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.6 KXH55524.1 - 1.5e-17 61.9 4.4 9.6e-08 31.4 0.4 5.4 6 0 0 6 6 6 3 EF-hand domain EF-hand_7 PF13499.6 KXH55524.1 - 1.9e-16 60.2 6.2 1.5e-09 38.2 0.6 3.2 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 KXH55524.1 - 1.1e-12 46.8 6.0 3.6e-06 26.2 1.3 4.4 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 KXH55524.1 - 2.3e-08 33.7 2.8 0.36 10.7 0.0 5.4 5 0 0 5 5 5 4 EF-hand domain pair EF-hand_9 PF14658.6 KXH55524.1 - 0.028 14.7 0.0 17 5.8 0.0 3.5 4 0 0 4 4 4 0 EF-hand domain FAA_hydrolase PF01557.18 KXH55525.1 - 2.3e-51 174.6 0.0 3.2e-51 174.1 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 KXH55525.1 - 1e-14 54.6 0.0 3.9e-14 52.7 0.0 1.9 2 0 0 2 2 2 1 Fumarylacetoacetase N-terminal PepX_C PF08530.10 KXH55526.1 - 4e-46 157.8 0.2 6e-46 157.2 0.2 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Peptidase_S15 PF02129.18 KXH55526.1 - 3.7e-39 134.9 0.1 5.6e-39 134.4 0.1 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.8 KXH55526.1 - 0.054 12.8 0.0 0.087 12.1 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Aldedh PF00171.22 KXH55528.1 - 1e-10 40.7 0.4 1.4e-09 37.0 0.4 2.0 1 1 0 1 1 1 1 Aldehyde dehydrogenase family LigB PF02900.18 KXH55528.1 - 3.3e-10 39.5 0.0 7.6e-10 38.3 0.0 1.6 1 1 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Med5 PF08689.10 KXH55529.1 - 1e-96 324.9 0.0 8.6e-96 321.9 0.0 2.4 1 1 0 1 1 1 1 Mediator complex subunit Med5 SSF PF00474.17 KXH55529.1 - 0.04 12.8 0.2 0.071 12.0 0.2 1.3 1 0 0 1 1 1 0 Sodium:solute symporter family Arm PF00514.23 KXH55530.1 - 9e-96 311.4 16.1 3.9e-13 48.9 0.0 8.4 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat IBB PF01749.20 KXH55530.1 - 2.8e-27 95.0 1.3 2.8e-27 95.0 1.3 1.8 2 0 0 2 2 1 1 Importin beta binding domain Arm_3 PF16186.5 KXH55530.1 - 1.3e-23 82.3 4.9 2.1e-23 81.6 4.2 1.7 2 0 0 2 2 2 1 Atypical Arm repeat HEAT_EZ PF13513.6 KXH55530.1 - 9.7e-23 80.3 8.6 7.4e-09 35.9 0.1 6.4 5 1 1 6 6 6 4 HEAT-like repeat HEAT_2 PF13646.6 KXH55530.1 - 5.3e-19 68.4 0.1 1.5e-08 34.9 0.0 5.3 1 1 5 6 6 6 4 HEAT repeats HEAT PF02985.22 KXH55530.1 - 1.1e-18 65.7 2.6 1.7e-05 24.7 0.0 7.1 8 0 0 8 8 8 4 HEAT repeat Arm_2 PF04826.13 KXH55530.1 - 8.5e-08 32.0 0.0 0.034 13.6 0.0 4.0 2 1 2 4 4 4 3 Armadillo-like Adaptin_N PF01602.20 KXH55530.1 - 3.7e-05 22.5 0.0 0.0022 16.6 0.0 2.6 1 1 1 2 2 2 1 Adaptin N terminal region V-ATPase_H_C PF11698.8 KXH55530.1 - 9.9e-05 22.4 0.0 2 8.5 0.0 4.3 3 2 2 5 5 5 2 V-ATPase subunit H HEAT_PBS PF03130.16 KXH55530.1 - 0.00076 19.9 0.2 1.7 9.6 0.0 4.4 4 0 0 4 4 4 1 PBS lyase HEAT-like repeat Cnd1 PF12717.7 KXH55530.1 - 0.0013 18.8 0.0 2.1 8.4 0.0 2.8 2 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 NopRA1 PF16201.5 KXH55530.1 - 0.028 14.0 0.0 7.4 6.1 0.0 3.8 2 2 2 4 4 4 0 Nucleolar pre-ribosomal-associated protein 1 RICTOR_V PF14668.6 KXH55530.1 - 0.037 14.2 4.9 3.4 8.0 0.1 4.7 3 2 3 6 6 6 0 Rapamycin-insensitive companion of mTOR, domain 5 Glycos_trans_3N PF02885.17 KXH55530.1 - 0.11 12.3 0.0 7.2 6.5 0.0 3.1 3 0 0 3 3 3 0 Glycosyl transferase family, helical bundle domain POT1PC PF16686.5 KXH55531.1 - 2e-48 164.2 0.4 2e-48 164.2 0.4 2.4 3 0 0 3 3 3 1 ssDNA-binding domain of telomere protection protein POT1 PF02765.17 KXH55531.1 - 2.4e-17 63.1 0.0 1e-16 61.0 0.0 2.0 2 0 0 2 2 2 1 Telomeric single stranded DNA binding POT1/CDC13 REPA_OB_2 PF16900.5 KXH55531.1 - 0.0015 18.4 0.0 0.0063 16.4 0.0 2.1 2 0 0 2 2 2 1 Replication protein A OB domain STAG PF08514.11 KXH55532.1 - 3.2e-28 97.9 2.8 7.9e-28 96.6 0.3 3.0 3 0 0 3 3 3 1 STAG domain HEAT_2 PF13646.6 KXH55532.1 - 0.00026 21.3 0.0 2.2 8.7 0.0 3.7 2 1 1 3 3 3 2 HEAT repeats T3SS_basalb_I PF17001.5 KXH55532.1 - 0.023 15.3 0.2 0.092 13.3 0.1 2.2 2 0 0 2 2 2 0 Type III secretion basal body protein I, YscI, HrpB, PscI Cnd1 PF12717.7 KXH55532.1 - 0.046 13.8 0.6 1.4 8.9 0.1 3.1 2 1 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 UreD PF01774.17 KXH55533.1 - 4.8e-76 255.4 0.0 5.8e-76 255.1 0.0 1.1 1 0 0 1 1 1 1 UreD urease accessory protein RNA_pol_Rpc4 PF05132.14 KXH55534.1 - 1.2e-31 110.1 0.1 1.2e-31 110.1 0.1 3.2 4 1 0 4 4 4 1 RNA polymerase III RPC4 FAD_binding_3 PF01494.19 KXH55535.1 - 1.4e-21 77.1 0.0 3e-12 46.5 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 KXH55535.1 - 2.1e-10 40.7 0.5 0.00032 20.4 0.0 2.3 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXH55535.1 - 4.5e-05 22.8 0.0 0.00035 19.9 0.0 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KXH55535.1 - 6.1e-05 22.5 0.2 0.013 14.9 0.0 3.0 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 KXH55535.1 - 0.00015 21.0 0.6 0.0029 16.8 0.6 2.2 1 1 1 2 2 2 1 FAD binding domain HI0933_like PF03486.14 KXH55535.1 - 0.00016 20.5 0.0 0.0099 14.6 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein Lycopene_cycl PF05834.12 KXH55535.1 - 0.00047 19.3 0.5 0.0044 16.1 0.5 2.0 1 1 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 KXH55535.1 - 0.0021 18.2 0.1 0.0057 16.8 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KXH55535.1 - 0.068 13.7 0.0 6.1 7.5 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KXH55535.1 - 0.21 10.4 0.2 0.32 9.8 0.2 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox_3 PF13738.6 KXH55535.1 - 0.25 10.6 0.1 0.37 10.0 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Abhydrolase_6 PF12697.7 KXH55537.1 - 1.3e-07 32.5 1.2 2.2e-07 31.7 1.2 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 KXH55537.1 - 8.1e-07 29.1 0.2 1.1e-05 25.4 0.2 2.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KXH55537.1 - 0.06 12.8 0.0 7.3 6.0 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KXH55537.1 - 0.063 12.5 0.0 0.69 9.1 0.0 2.0 2 0 0 2 2 2 0 Serine aminopeptidase, S33 MFS_1 PF07690.16 KXH55538.1 - 6.1e-31 107.6 57.1 3.7e-30 105.0 39.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2070 PF09843.9 KXH55538.1 - 1.4 7.1 10.3 2 6.6 10.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Zn_clus PF00172.18 KXH55539.1 - 0.00078 19.5 12.0 0.0014 18.7 12.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CHZ PF09649.10 KXH55539.1 - 0.0062 16.0 0.0 0.0062 16.0 0.0 1.9 2 0 0 2 2 2 1 Histone chaperone domain CHZ Forkhead PF00250.18 KXH55554.1 - 1.2e-18 67.1 0.1 3.8e-18 65.5 0.1 1.9 2 0 0 2 2 2 1 Forkhead domain Patatin PF01734.22 KXH55554.1 - 1.5e-11 44.8 0.3 4.7e-11 43.2 0.3 1.9 1 1 0 1 1 1 1 Patatin-like phospholipase CobW_C PF07683.14 KXH55554.1 - 0.04 13.9 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 Cobalamin synthesis protein cobW C-terminal domain zf-C3HC4_2 PF13923.6 KXH55554.1 - 1.2 9.0 4.0 4.2 7.3 4.0 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RHH_5 PF07878.11 KXH55598.1 - 0.07 13.0 0.1 0.16 11.9 0.0 1.6 2 0 0 2 2 2 0 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 zf-RVT PF13966.6 KXH55599.1 - 0.014 16.1 2.3 0.092 13.5 2.3 2.2 1 1 0 1 1 1 0 zinc-binding in reverse transcriptase PapC_N PF13954.6 KXH55599.1 - 0.1 12.6 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 PapC N-terminal domain zf-H2C2_2 PF13465.6 KXH55602.1 - 9.2e-12 44.8 18.1 5.7e-07 29.7 2.5 3.5 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.26 KXH55602.1 - 8e-09 35.5 23.6 0.0069 16.8 3.6 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXH55602.1 - 1.6e-07 31.5 20.6 0.053 14.4 2.4 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger Rad50_zn_hook PF04423.14 KXH55602.1 - 0.0013 18.5 2.5 0.055 13.3 0.6 2.6 2 0 0 2 2 2 1 Rad50 zinc hook motif zf-C2H2_6 PF13912.6 KXH55602.1 - 0.0017 18.3 17.6 0.099 12.7 0.1 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_9 PF16293.5 KXH55602.1 - 0.0049 16.7 3.9 1.2 9.1 0.2 3.3 2 1 1 3 3 3 1 C2H2 type zinc-finger (1 copy) ATG16 PF08614.11 KXH55602.1 - 0.014 15.6 0.0 0.014 15.6 0.0 2.8 3 1 0 4 4 3 0 Autophagy protein 16 (ATG16) Zn-ribbon_8 PF09723.10 KXH55602.1 - 0.034 14.3 5.6 0.12 12.6 1.7 2.4 2 0 0 2 2 2 0 Zinc ribbon domain Laminin_I PF06008.14 KXH55602.1 - 0.058 13.1 0.1 0.096 12.4 0.1 1.2 1 0 0 1 1 1 0 Laminin Domain I zf-Di19 PF05605.12 KXH55602.1 - 0.15 12.4 10.9 0.38 11.1 6.4 2.3 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding DZR PF12773.7 KXH55602.1 - 0.37 10.8 5.2 0.92 9.6 4.7 1.9 1 1 1 2 2 2 0 Double zinc ribbon zf-C2H2_jaz PF12171.8 KXH55602.1 - 0.38 11.1 14.3 5.6 7.4 3.0 4.1 4 1 0 4 4 4 0 Zinc-finger double-stranded RNA-binding FYDLN_acid PF09538.10 KXH55602.1 - 2 9.1 7.2 2.8 8.7 1.2 3.0 1 1 1 2 2 2 0 Protein of unknown function (FYDLN_acid) zf-C2HC_2 PF13913.6 KXH55602.1 - 2.9 7.9 7.4 0.15 12.0 0.7 2.2 2 0 0 2 2 2 0 zinc-finger of a C2HC-type AAA_13 PF13166.6 KXH55602.1 - 2.9 6.4 6.0 1.6 7.2 0.5 2.0 2 0 0 2 2 2 0 AAA domain GAGA PF09237.11 KXH55602.1 - 3.2 7.6 6.1 11 5.9 0.1 2.9 1 1 2 3 3 3 0 GAGA factor Zn_Tnp_IS1595 PF12760.7 KXH55602.1 - 3.4 7.7 7.7 4.6 7.3 2.9 2.3 2 0 0 2 2 2 0 Transposase zinc-ribbon domain DUF2197 PF09963.9 KXH55602.1 - 4.7 7.6 5.7 1.1 9.5 2.1 1.8 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) zf-UDP PF14569.6 KXH55602.1 - 7 6.8 7.4 14 5.9 0.3 2.7 1 1 1 2 2 2 0 Zinc-binding RING-finger zf-BED PF02892.15 KXH55602.1 - 8 6.6 8.4 6.4 6.9 4.3 2.5 1 1 1 2 2 2 0 BED zinc finger zinc_ribbon_9 PF14369.6 KXH55602.1 - 9.6 6.6 8.0 81 3.6 0.3 3.1 2 1 1 3 3 3 0 zinc-ribbon RabGAP-TBC PF00566.18 KXH55603.1 - 1.5e-31 109.8 0.0 3.5e-26 92.2 0.0 2.2 2 0 0 2 2 2 2 Rab-GTPase-TBC domain DUF4072 PF13284.6 KXH55603.1 - 0.015 15.7 1.8 0.14 12.6 1.4 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4072) Sulfate_transp PF00916.20 KXH55605.1 - 1.2e-106 356.7 25.8 1.6e-106 356.3 25.8 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KXH55605.1 - 7.2e-09 35.3 0.0 1.4e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 KXH55605.1 - 0.0039 17.6 3.4 0.0039 17.6 3.4 3.3 2 1 1 3 3 3 2 Molybdate transporter of MFS superfamily Zn_clus PF00172.18 KXH55671.1 - 3.1e-07 30.4 8.6 3.1e-07 30.4 8.6 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SAT PF16073.5 KXH55672.1 - 7.2e-76 255.1 0.2 7.2e-76 255.1 0.2 2.4 3 0 0 3 3 3 1 Starter unit:ACP transacylase in aflatoxin biosynthesis ketoacyl-synt PF00109.26 KXH55672.1 - 9.8e-75 251.4 0.0 2e-74 250.4 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 KXH55672.1 - 1.3e-45 156.3 0.0 2.2e-45 155.6 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KXH55672.1 - 1.8e-36 124.7 2.1 2e-36 124.6 0.6 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.20 KXH55672.1 - 2.4e-23 83.5 0.0 1.1e-22 81.3 0.0 2.2 2 1 0 2 2 2 1 Thioesterase domain PP-binding PF00550.25 KXH55672.1 - 2.6e-21 75.8 2.9 7.3e-11 42.3 0.2 2.6 2 0 0 2 2 2 2 Phosphopantetheine attachment site PS-DH PF14765.6 KXH55672.1 - 1.3e-20 73.8 0.0 2.3e-20 73.1 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Thiolase_N PF00108.23 KXH55672.1 - 0.00026 20.4 0.0 0.0012 18.3 0.0 2.0 2 0 0 2 2 2 1 Thiolase, N-terminal domain KAsynt_C_assoc PF16197.5 KXH55672.1 - 0.00043 20.7 0.0 0.0011 19.4 0.0 1.6 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Hydrolase_4 PF12146.8 KXH55672.1 - 0.01 15.1 0.3 0.13 11.5 0.0 2.4 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Ribosomal_60s PF00428.19 KXH55672.1 - 2.3 8.9 16.7 10 6.8 10.4 3.0 2 0 0 2 2 2 0 60s Acidic ribosomal protein Cyanate_lyase PF02560.14 KXH55721.1 - 2.2e-29 101.1 0.0 4.2e-29 100.2 0.0 1.4 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain HTH_31 PF13560.6 KXH55721.1 - 6.7e-05 23.2 0.0 9.6e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 KXH55721.1 - 0.0014 18.6 0.1 0.0023 18.0 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix Sigma70_r4_2 PF08281.12 KXH55721.1 - 0.0033 17.1 0.0 0.0066 16.1 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_38 PF13936.6 KXH55721.1 - 0.029 14.1 0.0 0.057 13.2 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain DUF3786 PF12654.7 KXH55721.1 - 0.044 13.4 0.0 0.074 12.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3786) Sigma70_r4 PF04545.16 KXH55721.1 - 0.062 12.8 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 Ebp2 PF05890.12 KXH55722.1 - 5.2e-89 298.4 16.3 5.2e-89 298.4 16.3 2.9 2 1 0 2 2 2 1 Eukaryotic rRNA processing protein EBP2 CPDase PF07823.11 KXH55722.1 - 0.043 13.5 0.0 0.076 12.7 0.0 1.4 1 0 0 1 1 1 0 Cyclic phosphodiesterase-like protein zf-MYND PF01753.18 KXH55723.1 - 1.3e-07 31.6 19.6 1.3e-07 31.6 19.6 2.1 2 0 0 2 2 2 1 MYND finger PIG-Y PF15159.6 KXH55724.1 - 4.5e-21 75.5 6.7 7e-21 74.9 6.7 1.3 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y Sdh_cyt PF01127.22 KXH55724.1 - 0.06 13.4 0.7 0.11 12.6 0.7 1.3 1 0 0 1 1 1 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Methyltransf_23 PF13489.6 KXH55795.1 - 0.079 12.8 0.0 0.09 12.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Kelch_5 PF13854.6 KXH55831.1 - 2.2e-10 40.3 13.9 3.1e-10 39.8 0.1 5.2 5 0 0 5 5 5 1 Kelch motif SKG6 PF08693.10 KXH55831.1 - 1.7e-06 27.3 0.2 3.4e-06 26.4 0.2 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Kelch_1 PF01344.25 KXH55831.1 - 0.0006 19.3 0.4 0.17 11.5 0.1 3.7 3 0 0 3 3 3 1 Kelch motif Kelch_2 PF07646.15 KXH55831.1 - 0.014 15.4 5.0 3.2 7.9 0.0 5.3 6 0 0 6 6 6 0 Kelch motif Kelch_6 PF13964.6 KXH55831.1 - 0.039 14.3 12.2 7.7 7.0 0.8 5.0 4 1 1 5 5 5 0 Kelch motif Amnionless PF14828.6 KXH55831.1 - 0.044 12.6 0.0 0.066 12.0 0.0 1.2 1 0 0 1 1 1 0 Amnionless CD99L2 PF12301.8 KXH55831.1 - 0.066 13.5 0.9 0.18 12.1 0.9 1.8 1 0 0 1 1 1 0 CD99 antigen like protein 2 Gram_pos_anchor PF00746.21 KXH55831.1 - 0.17 11.8 2.2 0.46 10.5 2.2 1.8 1 0 0 1 1 1 0 LPXTG cell wall anchor motif Kelch_3 PF13415.6 KXH55831.1 - 2.3 8.6 11.5 0.36 11.2 0.2 4.4 5 0 0 5 5 5 0 Galactose oxidase, central domain GCV_T PF01571.21 KXH55832.1 - 1.8e-05 24.3 0.0 3.1e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain DnaJ PF00226.31 KXH55833.1 - 9.8e-14 51.2 2.1 6.9e-13 48.5 0.6 2.5 2 0 0 2 2 2 1 DnaJ domain WDCP PF15390.6 KXH55833.1 - 2.2 6.6 4.9 2.9 6.1 4.9 1.2 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family SAD_SRA PF02182.17 KXH55834.1 - 1.1e-06 28.4 0.5 2.1e-06 27.5 0.1 1.6 2 0 0 2 2 2 1 SAD/SRA domain Catalase PF00199.19 KXH55835.1 - 4.8e-161 536.1 0.1 6e-161 535.8 0.1 1.1 1 0 0 1 1 1 1 Catalase Catalase_C PF18011.1 KXH55835.1 - 1.2e-47 161.3 0.7 1.9e-47 160.7 0.7 1.3 1 0 0 1 1 1 1 C-terminal domain found in long catalases Catalase-rel PF06628.12 KXH55835.1 - 5.7e-20 71.3 0.0 1.1e-19 70.4 0.0 1.5 1 0 0 1 1 1 1 Catalase-related immune-responsive Ribosomal_S8 PF00410.19 KXH55836.1 - 5.9e-22 78.0 0.0 7.8e-22 77.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 Ribosomal_L7Ae PF01248.26 KXH55837.1 - 4.4e-28 96.9 1.0 5.7e-28 96.5 1.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 KXH55837.1 - 0.09 12.7 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 PELOTA RNA binding domain Rotamase_3 PF13616.6 KXH55838.1 - 2.5e-17 63.5 0.1 5.2e-17 62.5 0.1 1.6 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 KXH55838.1 - 4.2e-16 59.7 0.8 1.2e-15 58.2 0.0 1.8 1 1 1 2 2 2 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 KXH55838.1 - 5.3e-05 24.0 0.5 7.6e-05 23.5 0.1 1.5 1 1 1 2 2 2 1 PPIC-type PPIASE domain DUF563 PF04577.14 KXH55839.1 - 1.2e-32 113.7 0.0 1.9e-32 113.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Asp PF00026.23 KXH55840.1 - 0.00093 18.7 0.2 0.0025 17.3 0.2 1.9 1 1 0 1 1 1 1 Eukaryotic aspartyl protease VSP PF03302.13 KXH55840.1 - 0.0027 16.6 2.5 0.0045 15.9 2.5 1.3 1 0 0 1 1 1 1 Giardia variant-specific surface protein GST_N_3 PF13417.6 KXH55841.1 - 6.1e-15 55.4 0.0 1.1e-14 54.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KXH55841.1 - 7.5e-15 55.0 0.0 1.8e-14 53.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KXH55841.1 - 3.2e-13 49.7 0.0 5.4e-13 49.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KXH55841.1 - 1.5e-10 41.2 0.0 3.1e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KXH55841.1 - 2.1e-10 40.7 0.1 3.9e-10 39.8 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KXH55841.1 - 6.6e-08 32.5 0.5 1.3e-07 31.6 0.5 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain NADH_u_ox_C PF12853.7 KXH55841.1 - 0.03 14.3 0.5 0.072 13.1 0.1 1.8 2 0 0 2 2 2 0 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit MFS_1 PF07690.16 KXH55842.1 - 5.4e-22 78.2 42.2 5.4e-22 78.2 42.2 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH55842.1 - 3.6e-08 32.7 29.1 1.7e-06 27.2 29.1 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter MMPL PF03176.15 KXH55842.1 - 0.01 14.8 1.4 0.025 13.5 1.4 1.6 1 0 0 1 1 1 0 MMPL family PhoLip_ATPase_C PF16212.5 KXH55843.1 - 4.7e-81 272.2 21.2 4.7e-81 272.2 21.2 2.3 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KXH55843.1 - 5.4e-27 93.3 7.1 1.3e-26 92.0 7.1 1.7 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 KXH55843.1 - 7.2e-12 45.2 0.0 3.8e-11 42.9 0.0 2.1 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KXH55843.1 - 5.1e-11 43.2 3.6 7.5e-07 29.6 0.9 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KXH55843.1 - 7.8e-08 32.0 0.0 1.8e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KXH55843.1 - 0.0016 18.2 0.5 0.013 15.2 0.3 2.2 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase DNA_III_psi PF03603.13 KXH55843.1 - 0.17 12.1 0.2 0.38 11.0 0.2 1.5 1 0 0 1 1 1 0 DNA polymerase III psi subunit Cript PF10235.9 KXH55844.1 - 1e-20 74.1 10.3 1.7e-20 73.4 10.3 1.3 1 0 0 1 1 1 1 Microtubule-associated protein CRIPT DZR PF12773.7 KXH55844.1 - 0.19 11.8 17.1 0.11 12.6 10.1 2.8 1 1 1 2 2 2 0 Double zinc ribbon DUF2039 PF10217.9 KXH55844.1 - 0.52 10.7 16.7 0.042 14.2 10.6 2.1 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) zf-ribbon_3 PF13248.6 KXH55844.1 - 0.59 9.6 13.8 0.73 9.3 3.0 3.2 2 1 1 3 3 3 0 zinc-ribbon domain CEBP_ZZ PF16366.5 KXH55844.1 - 1.3 9.3 8.1 0.3 11.4 4.2 1.8 2 0 0 2 2 2 0 Cytoplasmic polyadenylation element-binding protein ZZ domain zinc_ribbon_2 PF13240.6 KXH55844.1 - 1.9 8.3 14.1 2.2 8.1 1.9 3.2 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_15 PF17032.5 KXH55844.1 - 2.1 9.2 13.2 1.6 9.6 8.5 2.7 2 1 0 2 2 2 0 zinc-ribbon family zf-C3HC4_3 PF13920.6 KXH55844.1 - 5 7.1 12.3 8.8 6.3 8.1 2.7 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Abhydrolase_1 PF00561.20 KXH55845.1 - 1.9e-26 93.2 0.1 1.7e-20 73.7 0.2 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXH55845.1 - 9.2e-18 65.7 0.0 1.4e-17 65.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXH55845.1 - 2.3e-13 49.9 0.0 1.1e-12 47.8 0.0 1.8 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 KXH55845.1 - 0.057 13.2 0.0 0.35 10.6 0.0 2.1 2 1 1 3 3 3 0 Phospholipase/Carboxylesterase Abhydrolase_4 PF08386.10 KXH55845.1 - 0.076 13.1 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein Pinin_SDK_memA PF04696.13 KXH55846.1 - 9.2e-33 113.1 13.3 9.2e-33 113.1 13.3 2.8 3 1 0 3 3 3 1 pinin/SDK/memA/ protein conserved region ArAE_2_N PF10337.9 KXH55846.1 - 0.17 10.9 2.6 0.26 10.3 2.6 1.2 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal ATP-synt_E PF05680.12 KXH55846.1 - 4.8 7.6 16.8 2.3 8.6 3.3 3.5 3 1 0 3 3 3 0 ATP synthase E chain ING PF12998.7 KXH55846.1 - 8.6 7.0 10.2 27 5.4 3.7 2.4 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding PHF5 PF03660.14 KXH55847.1 - 3.9e-52 174.8 10.5 4.5e-52 174.6 10.5 1.0 1 0 0 1 1 1 1 PHF5-like protein PolC_DP2 PF03833.13 KXH55847.1 - 0.23 9.3 5.9 0.23 9.3 5.9 1.2 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DZR PF12773.7 KXH55847.1 - 2.9 8.0 15.5 6.5 6.9 2.2 3.0 1 1 1 2 2 2 0 Double zinc ribbon Pex26 PF07163.12 KXH55848.1 - 4e-05 23.1 3.1 0.0013 18.1 2.7 2.2 2 0 0 2 2 2 1 Pex26 protein Merozoite_SPAM PF07133.11 KXH55848.1 - 0.34 10.9 12.0 0.53 10.3 12.0 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) CDC45 PF02724.14 KXH55848.1 - 0.66 8.2 7.3 0.95 7.7 7.3 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF3381 PF11861.8 KXH55848.1 - 3.2 7.5 17.2 5.2 6.8 17.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) CAF1 PF04857.20 KXH55849.1 - 2.1e-79 267.0 0.0 2.6e-79 266.7 0.0 1.1 1 0 0 1 1 1 1 CAF1 family ribonuclease DNA_pol_A_exo1 PF01612.20 KXH55849.1 - 0.0034 17.1 0.0 0.042 13.6 0.1 2.3 2 0 0 2 2 2 1 3'-5' exonuclease DHC_N2 PF08393.13 KXH55849.1 - 0.035 13.2 0.1 0.18 10.8 0.0 2.0 2 0 0 2 2 2 0 Dynein heavy chain, N-terminal region 2 FAD_binding_3 PF01494.19 KXH56007.1 - 5.3e-47 160.7 0.0 7.3e-47 160.3 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KXH56007.1 - 4.3e-08 33.1 0.8 0.00076 19.2 0.3 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXH56007.1 - 2.4e-05 23.7 0.4 0.047 12.9 0.0 2.1 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXH56007.1 - 0.0015 17.4 0.0 0.0046 15.7 0.0 1.8 1 1 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.6 KXH56007.1 - 0.0035 17.5 0.0 0.0086 16.3 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KXH56007.1 - 0.0089 15.2 0.0 0.19 10.8 0.0 2.1 1 1 1 2 2 2 1 FAD binding domain SE PF08491.10 KXH56007.1 - 0.013 14.6 0.0 0.099 11.7 0.0 1.9 2 0 0 2 2 2 0 Squalene epoxidase Pyr_redox_3 PF13738.6 KXH56007.1 - 0.091 12.0 0.0 0.33 10.1 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXH56007.1 - 0.13 12.2 0.1 8.9 6.3 0.0 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KXH56007.1 - 0.18 10.8 0.1 0.69 8.9 0.0 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein UDPG_MGDP_dh_N PF03721.14 KXH56007.1 - 0.19 11.3 0.0 0.3 10.6 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Dioxygenase_C PF00775.21 KXH56008.1 - 9.4e-43 145.7 0.0 1.3e-42 145.3 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 KXH56008.1 - 4.6e-29 100.1 0.0 7.6e-29 99.4 0.0 1.4 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 KXH56008.1 - 6.4e-05 23.2 0.2 0.00015 22.0 0.2 1.5 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain Big_1 PF02369.16 KXH56008.1 - 0.028 14.4 0.0 0.059 13.4 0.0 1.5 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 1) Abhydrolase_3 PF07859.13 KXH56010.1 - 7.6e-27 94.5 0.0 1e-26 94.1 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KXH56010.1 - 9.7e-13 47.7 0.0 4.7e-12 45.4 0.0 1.8 1 1 0 1 1 1 1 Steryl acetyl hydrolase DUF3089 PF11288.8 KXH56010.1 - 0.0025 17.4 0.0 0.0048 16.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3089) COesterase PF00135.28 KXH56010.1 - 0.0039 16.1 0.0 0.0066 15.4 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family Hydrolase_4 PF12146.8 KXH56010.1 - 0.0079 15.5 0.0 0.12 11.6 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 COesterase PF00135.28 KXH56012.1 - 1.7e-64 218.6 0.0 2.2e-64 218.2 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXH56012.1 - 1.6e-07 31.5 0.5 4.1e-05 23.5 0.1 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KXH56012.1 - 0.0037 16.8 0.1 0.0067 15.9 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF4322 PF14210.6 KXH56012.1 - 0.13 12.1 0.1 0.25 11.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4322) FAD_binding_4 PF01565.23 KXH56013.1 - 5.4e-19 68.3 2.8 9.7e-19 67.5 2.0 1.9 1 1 1 2 2 2 1 FAD binding domain BBE PF08031.12 KXH56013.1 - 6.4e-11 42.2 0.4 1.5e-10 41.0 0.4 1.6 1 0 0 1 1 1 1 Berberine and berberine like zf-BED PF02892.15 KXH56023.1 - 0.002 18.1 0.7 0.057 13.4 0.5 2.5 2 0 0 2 2 2 1 BED zinc finger zf_UBZ PF18439.1 KXH56023.1 - 0.0062 16.1 0.0 0.01 15.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger zf-Di19 PF05605.12 KXH56023.1 - 0.2 12.0 0.0 0.87 9.9 0.0 1.9 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding RTA1 PF04479.13 KXH56118.1 - 2.8e-60 203.5 9.8 4.7e-60 202.7 9.8 1.3 1 0 0 1 1 1 1 RTA1 like protein NnrS PF05940.12 KXH56118.1 - 0.091 12.1 15.2 0.88 8.9 11.7 2.0 1 1 1 2 2 2 0 NnrS protein DUF3493 PF11998.8 KXH56118.1 - 0.63 10.3 3.6 15 5.8 0.2 3.5 3 1 0 3 3 3 0 Low psii accumulation1 / Rep27 DUF3007 PF11460.8 KXH56118.1 - 1.9 8.8 3.9 1.9 8.8 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3007) Ecm33 PF12454.8 KXH56119.1 - 0.83 9.8 4.9 4.7 7.4 0.2 2.6 2 0 0 2 2 2 0 GPI-anchored cell wall organization protein Oxidored_FMN PF00724.20 KXH56120.1 - 3.6e-36 125.1 0.0 5e-36 124.7 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family His_biosynth PF00977.21 KXH56120.1 - 0.0013 18.2 0.0 0.002 17.7 0.0 1.2 1 0 0 1 1 1 1 Histidine biosynthesis protein Thoc2 PF11732.8 KXH56120.1 - 0.022 14.8 0.0 0.039 14.0 0.0 1.3 1 0 0 1 1 1 0 Transcription- and export-related complex subunit Ank_2 PF12796.7 KXH56229.1 - 8e-32 109.7 7.6 3e-15 56.6 0.6 3.9 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXH56229.1 - 3.6e-24 84.8 1.1 2.5e-07 31.1 0.0 5.8 2 1 4 6 6 5 5 Ankyrin repeats (many copies) Ank PF00023.30 KXH56229.1 - 1.2e-20 73.0 5.9 0.0057 17.1 0.0 6.2 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 KXH56229.1 - 7.6e-18 64.4 1.1 0.0021 18.3 0.0 5.9 1 1 4 5 5 5 5 Ankyrin repeats (many copies) PNP_UDP_1 PF01048.20 KXH56229.1 - 1.7e-11 43.8 0.0 5.8e-11 42.1 0.0 2.0 1 1 0 1 1 1 1 Phosphorylase superfamily NACHT PF05729.12 KXH56229.1 - 1.6e-10 41.1 0.1 3.4e-10 40.1 0.1 1.6 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 KXH56229.1 - 1.6e-08 34.9 0.0 8.2e-08 32.6 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 KXH56229.1 - 1.4e-06 28.8 2.4 3e-06 27.7 0.2 2.7 3 0 0 3 3 3 1 AAA ATPase domain NB-ARC PF00931.22 KXH56229.1 - 0.00029 20.1 0.0 0.00066 18.9 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain ATPase_2 PF01637.18 KXH56229.1 - 0.0043 17.0 0.0 0.0074 16.2 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Parvo_NS1 PF01057.17 KXH56229.1 - 0.032 13.3 0.0 0.066 12.3 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 KAP_NTPase PF07693.14 KXH56229.1 - 0.068 12.4 0.0 2.1 7.5 0.0 2.2 1 1 0 2 2 2 0 KAP family P-loop domain AAA_14 PF13173.6 KXH56229.1 - 0.075 13.1 0.0 0.4 10.7 0.0 2.2 1 1 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 KXH56229.1 - 0.078 12.7 0.0 10 5.8 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.22 KXH56229.1 - 0.13 12.7 0.0 0.3 11.5 0.0 1.6 1 0 0 1 1 1 0 RNA helicase ResIII PF04851.15 KXH56229.1 - 0.18 11.8 0.0 0.34 10.9 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Pkinase PF00069.25 KXH56284.1 - 4.5e-36 124.6 0.0 6.6e-36 124.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXH56284.1 - 3.7e-18 65.7 0.0 9e-18 64.5 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KXH56284.1 - 5.5e-05 22.6 0.0 9.4e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KXH56284.1 - 0.017 15.0 0.1 0.053 13.4 0.1 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family Methyltransf_25 PF13649.6 KXH56286.1 - 7.9e-17 61.8 0.0 1.2e-16 61.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXH56286.1 - 5.6e-16 58.6 0.0 8.3e-16 58.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 KXH56286.1 - 8.5e-16 58.4 0.0 1.3e-15 57.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH56286.1 - 9.4e-13 48.2 0.0 1.2e-12 47.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH56286.1 - 1.7e-10 41.5 0.0 2.4e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXH56286.1 - 3.6e-08 33.4 0.0 5.3e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 KXH56286.1 - 1.6e-05 24.9 0.0 7.2e-05 22.7 0.0 1.9 2 0 0 2 2 2 1 Hypothetical methyltransferase MTS PF05175.14 KXH56286.1 - 0.0019 17.8 0.0 0.0031 17.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain MetW PF07021.12 KXH56286.1 - 0.0083 15.7 0.1 0.084 12.5 0.1 2.1 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW PCMT PF01135.19 KXH56286.1 - 0.023 14.4 0.0 0.034 13.9 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltr_RsmB-F PF01189.17 KXH56286.1 - 0.024 14.3 0.0 0.039 13.6 0.0 1.2 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F Condensation PF00668.20 KXH56288.1 - 1.6e-07 30.4 0.0 2.8e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Condensation domain ADH_zinc_N PF00107.26 KXH56289.1 - 4.5e-08 33.1 0.0 8.7e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXH56289.1 - 4.2e-07 29.8 0.2 2.6e-06 27.3 0.2 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KXH56289.1 - 0.012 16.6 0.0 0.021 15.9 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase p450 PF00067.22 KXH56290.1 - 1.1e-48 166.2 0.0 1.5e-48 165.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KXH56291.1 - 2.7e-25 89.0 0.0 2.1e-24 86.1 0.0 1.8 1 1 1 2 2 2 2 Cytochrome P450 VASP_tetra PF08776.11 KXH56291.1 - 0.02 14.5 0.6 0.036 13.6 0.6 1.4 1 0 0 1 1 1 0 VASP tetramerisation domain p450 PF00067.22 KXH56293.1 - 8.6e-58 196.2 0.0 1e-57 195.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 AMP-binding PF00501.28 KXH56294.1 - 7.8e-78 261.9 0.0 1.6e-77 260.9 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.26 KXH56294.1 - 1.3e-77 260.8 0.0 2.5e-77 259.9 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KXH56294.1 - 1.3e-53 181.6 0.0 1.2e-49 168.7 0.0 2.6 2 0 0 2 2 2 2 KR domain Condensation PF00668.20 KXH56294.1 - 7.1e-53 179.9 0.0 1.2e-52 179.1 0.0 1.3 1 0 0 1 1 1 1 Condensation domain Acyl_transf_1 PF00698.21 KXH56294.1 - 1.5e-49 169.3 0.2 3.1e-49 168.2 0.2 1.5 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 KXH56294.1 - 5.3e-42 144.1 0.6 8.3e-42 143.4 0.6 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase NAD_binding_4 PF07993.12 KXH56294.1 - 1.5e-36 125.9 0.0 7e-36 123.7 0.0 2.0 2 0 0 2 2 2 1 Male sterility protein Ketoacyl-synt_C PF02801.22 KXH56294.1 - 1.4e-32 112.1 0.2 4.1e-32 110.7 0.2 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 KXH56294.1 - 7.7e-19 68.3 0.0 2.4e-18 66.7 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.21 KXH56294.1 - 2.1e-18 66.7 0.0 6.6e-16 58.5 0.0 3.1 3 0 0 3 3 3 1 NAD dependent epimerase/dehydratase family KAsynt_C_assoc PF16197.5 KXH56294.1 - 8.6e-16 58.4 0.0 2.7e-15 56.8 0.0 1.9 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_25 PF13649.6 KXH56294.1 - 3.5e-14 53.3 0.0 3.5e-13 50.1 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain PP-binding PF00550.25 KXH56294.1 - 3.5e-14 52.9 0.6 9.6e-09 35.5 0.1 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site adh_short PF00106.25 KXH56294.1 - 2.6e-13 49.9 0.0 5.8e-09 35.7 0.0 2.8 3 0 0 3 3 3 2 short chain dehydrogenase Methyltransf_23 PF13489.6 KXH56294.1 - 3.9e-13 49.6 0.0 8.1e-13 48.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH56294.1 - 7.7e-13 48.9 0.0 2.4e-12 47.3 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH56294.1 - 2.3e-09 37.2 0.0 5.1e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXH56294.1 - 1.7e-07 30.9 0.0 3.2e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family GDP_Man_Dehyd PF16363.5 KXH56294.1 - 9.3e-07 28.5 0.0 7.7e-06 25.5 0.0 2.1 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KXH56294.1 - 3.7e-06 26.1 0.0 2.5e-05 23.5 0.0 2.2 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Thiolase_N PF00108.23 KXH56294.1 - 4.3e-05 23.0 0.0 8.9e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_16 PF10294.9 KXH56294.1 - 0.00035 20.3 0.0 0.00081 19.2 0.0 1.5 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 KXH56294.1 - 0.0023 17.5 0.0 0.0059 16.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain DUF938 PF06080.12 KXH56294.1 - 0.0092 15.8 0.0 0.025 14.4 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_33 PF10017.9 KXH56294.1 - 0.042 13.0 0.0 0.083 12.0 0.0 1.4 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent Sacchrp_dh_NADP PF03435.18 KXH56294.1 - 0.046 14.0 0.0 1.2 9.4 0.0 2.9 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain RrnaAD PF00398.20 KXH56294.1 - 0.16 11.0 0.0 0.3 10.1 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase NNMT_PNMT_TEMT PF01234.17 KXH56294.1 - 0.18 11.0 0.0 0.7 9.0 0.0 1.9 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family ACP_syn_III PF08545.10 KXH56294.1 - 0.24 11.3 3.2 0.49 10.3 0.4 3.0 4 0 0 4 4 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III TRAM_LAG1_CLN8 PF03798.16 KXH56295.1 - 6.3e-35 120.7 14.6 6.3e-35 120.7 14.6 1.8 3 0 0 3 3 3 1 TLC domain TRAM1 PF08390.11 KXH56295.1 - 3.1e-24 84.4 1.3 4.3e-24 83.9 0.1 2.0 2 0 0 2 2 2 1 TRAM1-like protein TRAM_LAG1_CLN8 PF03798.16 KXH56296.1 - 6.9e-41 140.2 13.3 6.9e-41 140.2 13.3 1.4 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 KXH56296.1 - 9.3e-22 76.5 0.1 2.4e-21 75.2 0.1 1.7 1 0 0 1 1 1 1 TRAM1-like protein DoxX_3 PF13781.6 KXH56296.1 - 0.018 15.7 0.3 0.067 13.8 0.3 2.0 1 0 0 1 1 1 0 DoxX-like family Mito_carr PF00153.27 KXH56297.1 - 2.1e-40 136.5 8.3 3.2e-17 62.2 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein SnoaL PF07366.12 KXH56298.1 - 4.4e-26 91.1 0.3 3.1e-16 59.3 0.0 2.1 2 0 0 2 2 2 2 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 KXH56298.1 - 7.6e-09 36.1 0.1 0.0016 19.0 0.0 2.3 2 0 0 2 2 2 2 SnoaL-like domain DUF2666 PF10869.8 KXH56298.1 - 0.081 13.1 0.1 15 5.8 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2666) Glyco_hydro_61 PF03443.14 KXH56299.1 - 2.1e-56 191.2 0.0 2.5e-56 190.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Pkinase PF00069.25 KXH56300.1 - 7.4e-24 84.5 0.0 1.2e-23 83.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXH56300.1 - 1.3e-10 41.0 0.0 2.5e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase NuiA PF07924.11 KXH56301.1 - 0.029 14.8 0.0 0.079 13.4 0.0 1.7 1 0 0 1 1 1 0 Nuclease A inhibitor-like protein HEXIM PF15313.6 KXH56301.1 - 0.88 9.7 7.0 0.49 10.6 0.2 2.7 2 0 0 2 2 2 0 Hexamethylene bis-acetamide-inducible protein HeLo PF14479.6 KXH56301.1 - 0.89 9.4 8.5 0.2 11.4 0.1 2.7 2 1 0 3 3 3 0 Prion-inhibition and propagation Peptidase_S8 PF00082.22 KXH56302.1 - 9.9e-11 41.4 0.5 6.3e-09 35.5 0.5 2.9 1 1 0 1 1 1 1 Subtilase family IDEAL PF08858.10 KXH56304.1 - 0.0074 16.0 0.4 0.015 15.1 0.4 1.4 1 0 0 1 1 1 1 IDEAL domain IMPa_helical PF18642.1 KXH56304.1 - 0.016 15.6 0.0 0.03 14.7 0.0 1.4 1 0 0 1 1 1 0 Immunomodulating metalloprotease helical domain CorA PF01544.18 KXH56306.1 - 7.5e-06 25.5 0.2 2.2e-05 23.9 0.2 1.8 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF4472 PF14739.6 KXH56306.1 - 0.17 12.6 0.4 17 6.2 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4472) Glyco_hydro_28 PF00295.17 KXH56307.1 - 8.5e-32 110.5 1.6 7.6e-30 104.1 1.6 2.2 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.6 KXH56307.1 - 0.19 11.6 9.3 0.69 9.7 7.9 2.3 1 1 0 2 2 2 0 Right handed beta helix region Pectate_lyase PF03211.13 KXH56308.1 - 1.5e-79 266.2 9.1 1.9e-79 265.9 9.1 1.1 1 0 0 1 1 1 1 Pectate lyase IBR PF01485.21 KXH56309.1 - 2.9e-08 33.8 40.3 7.3e-05 22.9 6.9 3.6 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain zf-C3HC4_3 PF13920.6 KXH56309.1 - 0.00023 20.9 5.7 0.00023 20.9 5.7 3.7 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXH56309.1 - 0.0012 18.8 6.9 0.0012 18.8 6.9 4.2 3 2 1 4 4 4 1 zinc-RING finger domain zf-RING_2 PF13639.6 KXH56309.1 - 0.0027 18.0 6.6 0.0027 18.0 6.6 3.8 3 0 0 3 3 3 1 Ring finger domain adh_short PF00106.25 KXH56310.1 - 6.9e-54 182.3 0.3 9.1e-54 181.9 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXH56310.1 - 4.6e-41 140.9 0.5 9e-41 139.9 0.5 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH56310.1 - 4.3e-12 46.3 0.2 7.6e-12 45.5 0.2 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KXH56310.1 - 0.014 14.9 0.6 0.085 12.3 0.6 2.1 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KXH56310.1 - 0.019 14.1 0.1 0.027 13.6 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF1482 PF07358.11 KXH56310.1 - 0.066 13.1 0.1 0.14 12.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1482) PCEMA1 PF07418.11 KXH56310.1 - 0.1 12.1 0.1 0.99 8.9 0.0 2.3 2 1 1 3 3 3 0 Acidic phosphoprotein precursor PCEMA1 PMSR PF01625.21 KXH56311.1 - 2.1e-60 203.3 0.3 2.5e-60 203.1 0.3 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Bax1-I PF01027.20 KXH56312.1 - 3.8e-37 128.2 9.9 6.1e-37 127.5 9.9 1.2 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 MF_alpha_N PF05436.11 KXH56313.1 - 0.042 13.7 0.1 0.042 13.7 0.1 2.0 1 1 1 2 2 2 0 Mating factor alpha precursor N-terminus PepSY_2 PF13670.6 KXH56313.1 - 6.5 6.8 11.7 2.8 8.0 1.0 2.1 1 1 1 2 2 2 0 Peptidase propeptide and YPEB domain cNMPbd_u2 PF16643.5 KXH56315.1 - 6e-39 134.0 20.9 6e-39 134.0 20.9 2.0 2 0 0 2 2 2 1 Unstructured region on cNMP-binding protein cNMP_binding PF00027.29 KXH56315.1 - 1.2e-34 118.2 0.0 5.8e-18 64.7 0.0 2.8 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain LRR_6 PF13516.6 KXH56315.1 - 2.5e-08 33.3 7.4 0.17 12.0 0.0 6.4 7 0 0 7 7 7 3 Leucine Rich repeat LRR_4 PF12799.7 KXH56315.1 - 2.9e-08 33.9 2.6 0.022 15.2 0.0 5.4 5 2 2 7 7 7 3 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KXH56315.1 - 4.8e-05 23.2 0.6 0.00021 21.1 0.0 2.3 2 0 0 2 2 2 1 F-box-like LRR_1 PF00560.33 KXH56315.1 - 0.001 19.3 13.6 9.4 7.2 0.0 7.4 8 0 0 8 8 8 2 Leucine Rich Repeat LRR_8 PF13855.6 KXH56315.1 - 0.0014 18.3 0.5 4.5 7.1 0.0 4.2 3 1 2 5 5 5 2 Leucine rich repeat F-box PF00646.33 KXH56315.1 - 0.0015 18.4 0.1 0.0015 18.4 0.1 2.9 3 0 0 3 3 3 1 F-box domain MNSV_P7B PF06692.11 KXH56316.1 - 0.28 11.2 2.1 13 5.8 0.2 2.5 2 0 0 2 2 2 0 Melon necrotic spot virus P7B protein HET PF06985.11 KXH56317.1 - 2.4e-12 47.4 5.6 5.1e-10 39.9 0.9 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) AAA PF00004.29 KXH56318.1 - 1.5e-18 67.5 0.1 1.8e-16 60.7 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KXH56318.1 - 0.00049 20.5 0.0 0.0016 18.9 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KXH56318.1 - 0.0009 19.5 1.4 0.015 15.5 0.1 3.2 2 1 1 3 3 3 1 AAA domain AAA_5 PF07728.14 KXH56318.1 - 0.018 15.0 0.0 0.049 13.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 KXH56318.1 - 0.042 13.6 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Zot PF05707.12 KXH56318.1 - 0.048 13.3 0.2 1 9.0 0.0 2.4 1 1 0 2 2 2 0 Zonular occludens toxin (Zot) Torsin PF06309.11 KXH56318.1 - 0.05 13.7 0.0 0.13 12.3 0.0 1.7 1 0 0 1 1 1 0 Torsin AAA_33 PF13671.6 KXH56318.1 - 0.083 13.1 0.1 0.4 10.8 0.1 2.2 1 0 0 1 1 1 0 AAA domain Phage_int_SAM_5 PF13102.6 KXH56318.1 - 0.096 13.0 0.2 9.4 6.7 0.0 3.0 2 1 1 3 3 3 0 Phage integrase SAM-like domain Sigma54_activat PF00158.26 KXH56318.1 - 0.1 12.3 0.3 0.3 10.8 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF1593 PF07632.11 KXH56319.1 - 0.096 12.1 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1593) NPP1 PF05630.11 KXH56320.1 - 5.3e-09 36.5 2.4 7.7e-09 36.0 1.1 1.8 1 1 1 2 2 2 1 Necrosis inducing protein (NPP1) Toprim_Crpt PF13342.6 KXH56320.1 - 0.17 11.9 0.0 0.25 11.3 0.0 1.3 1 0 0 1 1 1 0 C-terminal repeat of topoisomerase DUF2235 PF09994.9 KXH56321.1 - 1.5e-84 283.8 0.3 2.8e-47 161.5 0.0 2.2 2 0 0 2 2 2 2 Uncharacterized alpha/beta hydrolase domain (DUF2235) MFS_1 PF07690.16 KXH56322.1 - 4.8e-31 108.0 28.4 4.8e-31 108.0 28.4 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily ETRAMP PF09716.10 KXH56322.1 - 2.1 8.5 5.0 47 4.1 1.6 3.1 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Glyco_hydro_125 PF06824.11 KXH56323.1 - 7.8e-179 594.9 0.0 9.1e-179 594.7 0.0 1.0 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) Ank_2 PF12796.7 KXH56325.1 - 6.1e-50 167.7 0.2 7.6e-16 58.5 0.0 4.9 1 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 KXH56325.1 - 4.3e-48 159.7 7.6 0.00017 21.9 0.0 9.5 9 0 0 9 9 9 9 Ankyrin repeat Ank_4 PF13637.6 KXH56325.1 - 7e-46 154.0 1.6 9.5e-10 38.8 0.0 6.3 2 1 3 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXH56325.1 - 9e-40 134.2 12.1 7.4e-09 35.7 0.0 7.5 2 1 6 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXH56325.1 - 4.5e-39 128.0 1.1 0.00068 19.9 0.0 9.5 9 0 0 9 9 9 7 Ankyrin repeat TFIIA PF03153.13 KXH56325.1 - 0.025 14.6 4.7 0.042 13.9 4.7 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TPR_1 PF00515.28 KXH56326.1 - 2.7e-44 147.2 15.8 2.6e-07 30.2 0.1 9.1 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_2 PF07719.17 KXH56326.1 - 2.2e-35 117.9 15.4 7.5e-05 22.6 0.0 9.4 9 0 0 9 9 9 7 Tetratricopeptide repeat STI1 PF17830.1 KXH56326.1 - 1.1e-34 118.1 13.9 4.5e-19 68.1 1.6 3.0 3 0 0 3 3 2 2 STI1 domain TPR_11 PF13414.6 KXH56326.1 - 2.5e-23 81.5 10.8 0.00023 20.8 0.2 8.7 5 2 3 8 8 8 7 TPR repeat TPR_8 PF13181.6 KXH56326.1 - 8.5e-18 63.0 18.6 0.0004 20.4 0.1 8.1 8 0 0 8 8 7 5 Tetratricopeptide repeat TPR_16 PF13432.6 KXH56326.1 - 7.1e-16 58.6 1.0 0.0033 18.0 0.0 5.8 4 1 2 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 KXH56326.1 - 1.6e-15 57.2 12.2 1.8e-10 40.9 0.2 5.2 3 3 2 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 KXH56326.1 - 5.6e-14 52.4 7.4 2.8e-05 24.5 0.0 6.0 6 1 1 7 7 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 KXH56326.1 - 8.4e-13 48.0 5.1 1.4 9.9 0.0 8.1 6 2 3 9 9 8 3 Tetratricopeptide repeat TPR_17 PF13431.6 KXH56326.1 - 1.7e-12 46.8 3.2 0.063 13.7 0.2 7.6 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 KXH56326.1 - 7.1e-12 44.5 7.9 0.0012 18.7 0.0 7.3 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_9 PF13371.6 KXH56326.1 - 8e-11 41.9 0.0 0.0009 19.3 0.0 4.4 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 KXH56326.1 - 5e-06 26.2 9.0 0.029 14.3 0.0 5.9 5 1 1 6 6 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 KXH56326.1 - 0.00039 20.9 12.3 2.4 9.0 0.0 7.3 8 0 0 8 8 6 1 Tetratricopeptide repeat SHNi-TPR PF10516.9 KXH56326.1 - 0.012 15.1 0.6 1.8 8.1 0.1 3.8 4 0 0 4 4 4 0 SHNi-TPR TPR_MalT PF17874.1 KXH56326.1 - 0.013 14.9 0.2 0.074 12.4 0.0 2.3 3 0 0 3 3 3 0 MalT-like TPR region Fis1_TPR_C PF14853.6 KXH56326.1 - 0.013 15.6 1.0 22 5.2 0.1 5.2 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat ANAPC3 PF12895.7 KXH56326.1 - 0.045 14.0 0.7 0.045 14.0 0.7 2.8 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_3 PF07720.12 KXH56326.1 - 0.071 13.1 4.5 0.28 11.2 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF5486 PF17588.2 KXH56326.1 - 0.073 13.0 4.0 0.82 9.6 1.6 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5486) RPN7 PF10602.9 KXH56326.1 - 0.09 12.5 4.5 0.28 10.9 0.5 3.2 3 2 0 3 3 2 0 26S proteasome subunit RPN7 TPM_phosphatase PF04536.14 KXH56326.1 - 4.1 7.6 7.7 31 4.7 0.0 4.2 5 0 0 5 5 4 0 TPM domain MIT PF04212.18 KXH56326.1 - 9.4 6.4 20.8 4.4 7.5 0.9 6.6 6 3 0 6 6 6 0 MIT (microtubule interacting and transport) domain Peptidase_C12 PF01088.21 KXH56327.1 - 1.3e-49 168.8 0.0 1.5e-49 168.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Hemerythrin PF01814.23 KXH56328.1 - 2.3e-07 31.5 0.1 3.1e-07 31.1 0.1 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Ctr PF04145.15 KXH56329.1 - 4e-40 137.8 0.2 5.3e-40 137.5 0.2 1.2 1 0 0 1 1 1 1 Ctr copper transporter family YfhO PF09586.10 KXH56329.1 - 9.1 4.4 8.1 15 3.7 8.1 1.2 1 0 0 1 1 1 0 Bacterial membrane protein YfhO TauD PF02668.16 KXH56330.1 - 3.7e-45 154.8 0.3 4.5e-45 154.5 0.3 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family zf-C2H2_4 PF13894.6 KXH56331.1 - 0.16 12.9 4.6 0.81 10.7 0.1 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KXH56331.1 - 3.6 8.2 8.2 3 8.5 0.1 3.4 3 0 0 3 3 3 0 Zinc finger, C2H2 type Fungal_trans PF04082.18 KXH56332.1 - 1.4e-06 27.6 0.3 4.6e-06 25.9 0.3 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 KXH56333.1 - 1.5e-33 116.2 26.3 1.5e-33 116.2 26.3 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily AtuA PF07287.11 KXH56334.1 - 2.1e-128 428.0 0.0 2.6e-128 427.7 0.0 1.1 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA Fungal_trans PF04082.18 KXH56335.1 - 2.2e-16 59.7 0.0 4.5e-16 58.7 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH56335.1 - 7.4e-09 35.6 11.9 1.4e-08 34.7 11.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Nnf1 PF03980.14 KXH56335.1 - 0.018 15.4 0.7 0.041 14.3 0.7 1.6 1 0 0 1 1 1 0 Nnf1 DUF4140 PF13600.6 KXH56335.1 - 0.23 11.9 1.3 0.52 10.8 1.3 1.5 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DivIC PF04977.15 KXH56335.1 - 0.27 11.0 3.7 0.56 10.0 3.7 1.5 1 0 0 1 1 1 0 Septum formation initiator DUF4250 PF14056.6 KXH56335.1 - 0.73 9.8 3.8 7.7 6.6 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4250) Peptidase_M28 PF04389.17 KXH56336.1 - 1.5e-37 129.2 0.0 2.3e-37 128.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KXH56336.1 - 1.8e-10 40.7 0.2 4e-10 39.6 0.2 1.6 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 KXH56336.1 - 0.0039 16.9 0.0 0.0074 16.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Gly-rich_Ago1 PF12764.7 KXH56336.1 - 0.037 14.8 0.5 0.076 13.8 0.5 1.4 1 0 0 1 1 1 0 Glycine-rich region of argonaut Zip PF02535.22 KXH56337.1 - 5.4e-54 183.6 1.0 6.5e-54 183.4 1.0 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter MGC-24 PF05283.11 KXH56337.1 - 0.033 14.6 0.0 0.073 13.5 0.0 1.5 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin RNA_pol_Rpc34 PF05158.12 KXH56338.1 - 7.9e-101 337.8 0.0 1e-100 337.4 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit RPA_C PF08784.11 KXH56338.1 - 0.021 15.5 0.2 0.13 12.9 0.0 2.4 3 1 1 4 4 4 0 Replication protein A C terminal Pro_isomerase PF00160.21 KXH56339.1 - 4.6e-42 144.0 0.3 5.7e-42 143.7 0.3 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ENTH PF01417.20 KXH56340.1 - 4.1e-46 156.1 0.1 6.5e-46 155.4 0.1 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 KXH56340.1 - 0.00069 18.7 0.0 0.00094 18.2 0.0 1.2 1 0 0 1 1 1 1 ANTH domain DUF5102 PF17104.5 KXH56340.1 - 0.11 12.5 4.3 1.1 9.2 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5102) MARVEL PF01284.23 KXH56341.1 - 0.032 14.3 10.3 0.058 13.4 10.3 1.4 1 0 0 1 1 1 0 Membrane-associating domain Fungal_trans_2 PF11951.8 KXH56342.1 - 9.1e-59 199.2 0.4 9.1e-59 199.2 0.4 1.9 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH56342.1 - 1.3e-07 31.6 6.4 2.9e-07 30.5 6.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAM163 PF15069.6 KXH56342.1 - 0.51 10.8 4.5 0.15 12.5 0.5 2.1 2 0 0 2 2 2 0 FAM163 family Lin-8 PF03353.15 KXH56342.1 - 7.8 6.0 6.9 14 5.1 6.9 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Pkinase PF00069.25 KXH56343.1 - 5.1e-23 81.8 0.0 7.6e-23 81.2 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXH56343.1 - 6e-13 48.7 0.0 9.4e-13 48.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXH56344.1 - 1.8e-18 66.8 0.0 3.4e-18 66.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXH56344.1 - 2.4e-08 33.6 0.0 4.6e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HET PF06985.11 KXH56345.1 - 5.8e-21 75.4 0.0 1.1e-20 74.5 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ORC3_N PF07034.11 KXH56346.1 - 0.21 10.6 0.8 0.92 8.5 0.1 1.9 2 0 0 2 2 2 0 Origin recognition complex (ORC) subunit 3 N-terminus CDC45 PF02724.14 KXH56346.1 - 1.1 7.5 10.4 1.3 7.2 10.4 1.1 1 0 0 1 1 1 0 CDC45-like protein PDCD2_C PF04194.13 KXH56346.1 - 1.1 9.3 7.1 1.7 8.7 7.1 1.2 1 0 0 1 1 1 0 Programmed cell death protein 2, C-terminal putative domain CobT PF06213.12 KXH56346.1 - 1.2 8.5 15.1 1.7 8.0 15.1 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF4746 PF15928.5 KXH56346.1 - 1.4 8.3 7.9 1.9 7.9 7.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Nop14 PF04147.12 KXH56346.1 - 1.7 6.7 14.4 2 6.5 14.4 1.0 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 KXH56346.1 - 2.3 7.5 17.4 3.1 7.2 17.4 1.1 1 0 0 1 1 1 0 SDA1 YL1 PF05764.13 KXH56346.1 - 3.3 7.8 15.7 4.9 7.2 15.7 1.2 1 0 0 1 1 1 0 YL1 nuclear protein DUF4440 PF14534.6 KXH56347.1 - 9.4e-12 45.3 0.0 1.1e-11 45.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) Cutinase PF01083.22 KXH56350.1 - 2.3e-48 164.5 4.7 2.8e-48 164.2 4.7 1.0 1 0 0 1 1 1 1 Cutinase VirJ PF06057.11 KXH56350.1 - 0.0014 18.6 0.0 0.0021 18.0 0.0 1.4 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) PE-PPE PF08237.11 KXH56350.1 - 0.012 15.2 0.1 0.017 14.7 0.1 1.3 1 0 0 1 1 1 0 PE-PPE domain FSH1 PF03959.13 KXH56350.1 - 0.11 12.1 0.0 0.32 10.6 0.0 1.7 2 0 0 2 2 2 0 Serine hydrolase (FSH1) PAF-AH_p_II PF03403.13 KXH56351.1 - 3.2e-38 131.2 0.0 4.6e-38 130.7 0.0 1.1 1 0 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Hydrolase_4 PF12146.8 KXH56351.1 - 0.00072 18.9 0.6 0.012 14.9 0.0 2.5 2 1 1 3 3 3 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KXH56351.1 - 0.0021 18.7 0.0 0.0021 18.7 0.0 2.1 2 1 0 2 2 2 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.7 KXH56351.1 - 0.0039 16.2 0.0 0.03 13.2 0.0 2.1 1 1 0 1 1 1 1 Chlorophyllase enzyme Esterase PF00756.20 KXH56351.1 - 0.038 13.6 0.0 3.5 7.2 0.0 2.3 2 0 0 2 2 2 0 Putative esterase Abhydrolase_3 PF07859.13 KXH56351.1 - 0.11 12.4 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF4267 PF14087.6 KXH56352.1 - 0.047 13.8 2.8 0.094 12.8 2.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4267) CHORD PF04968.12 KXH56354.1 - 0.014 16.1 0.1 0.014 16.1 0.1 2.8 2 1 0 2 2 2 0 CHORD Protamine_3 PF08188.11 KXH56357.1 - 0.017 15.3 4.1 0.035 14.3 4.1 1.5 1 0 0 1 1 1 0 Spermatozal protamine family JAB PF01398.21 KXH56360.1 - 1.8e-32 111.8 0.0 3.2e-32 111.0 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 KXH56360.1 - 6.4e-12 45.9 0.4 1.3e-11 44.9 0.4 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 KXH56360.1 - 3e-07 30.2 0.0 5.4e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain COX2_TM PF02790.15 KXH56361.1 - 0.1 12.8 2.4 0.12 12.6 1.4 1.5 2 0 0 2 2 2 0 Cytochrome C oxidase subunit II, transmembrane domain Hist_deacetyl PF00850.19 KXH56362.1 - 5.1e-81 272.5 0.0 7.7e-81 271.9 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain Nitrate_red_gam PF02665.14 KXH56363.1 - 0.25 10.8 12.2 0.45 10.0 1.3 2.2 1 1 1 2 2 2 0 Nitrate reductase gamma subunit GMC_oxred_N PF00732.19 KXH56364.1 - 1.1e-51 176.0 0.0 1.4e-51 175.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXH56364.1 - 9.6e-35 120.2 0.0 1.6e-34 119.5 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KXH56364.1 - 0.00067 18.8 0.2 0.0016 17.6 0.2 1.6 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KXH56364.1 - 0.0038 16.5 1.7 0.5 9.5 0.1 2.6 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXH56364.1 - 0.0048 17.1 0.3 0.015 15.5 0.3 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXH56364.1 - 0.009 15.6 0.9 0.054 13.1 0.2 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase p450 PF00067.22 KXH56365.1 - 1.8e-35 122.6 0.0 4.1e-34 118.1 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 CTD_bind PF04818.13 KXH56365.1 - 0.2 12.5 0.4 6.6 7.6 0.0 3.0 3 0 0 3 3 3 0 RNA polymerase II-binding domain. MFS_1 PF07690.16 KXH56366.1 - 3.1e-23 82.3 36.3 2.9e-17 62.6 17.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4538 PF15061.6 KXH56366.1 - 0.057 13.2 0.6 6.6 6.6 0.0 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4538) Sugar_tr PF00083.24 KXH56367.1 - 3.6e-82 276.6 15.2 4.2e-82 276.4 15.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH56367.1 - 6.1e-31 107.6 19.5 8.5e-31 107.1 19.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KXH56367.1 - 1.8e-05 23.4 5.5 4.9e-05 21.9 1.4 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Phage_holin_3_2 PF04550.12 KXH56367.1 - 0.021 15.4 1.4 0.081 13.5 1.4 2.0 1 0 0 1 1 1 0 Phage holin family 2 Ada_Zn_binding PF02805.16 KXH56368.1 - 9.5e-27 92.8 1.6 1.4e-26 92.3 1.6 1.2 1 0 0 1 1 1 1 Metal binding domain of Ada HTH_18 PF12833.7 KXH56368.1 - 0.0011 19.2 0.2 0.0029 17.8 0.1 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_AraC PF00165.23 KXH56368.1 - 0.0031 17.6 1.5 0.005 16.9 0.0 2.1 3 0 0 3 3 3 1 Bacterial regulatory helix-turn-helix proteins, AraC family PQ-loop PF04193.14 KXH56369.1 - 1.4e-22 79.2 4.3 1.6e-17 63.0 0.2 2.7 3 0 0 3 3 3 2 PQ loop repeat Sigma_reg_C PF13791.6 KXH56369.1 - 0.066 13.4 0.0 0.096 12.9 0.0 1.2 1 0 0 1 1 1 0 Sigma factor regulator C-terminal Peptidase_S28 PF05577.12 KXH56370.1 - 4.8e-47 160.7 0.1 2.6e-38 132.0 0.0 2.0 2 0 0 2 2 2 2 Serine carboxypeptidase S28 GMC_oxred_N PF00732.19 KXH56371.1 - 1.5e-48 165.7 0.1 1.9e-48 165.4 0.1 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXH56371.1 - 9.8e-37 126.7 0.0 1.5e-36 126.1 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KXH56371.1 - 0.00091 18.4 0.1 0.0026 16.9 0.0 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KXH56371.1 - 0.0035 16.6 0.1 0.0075 15.5 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXH56371.1 - 0.0047 17.1 0.2 0.013 15.8 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXH56371.1 - 0.11 12.0 1.3 0.19 11.2 0.6 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase HHH_5 PF14520.6 KXH56371.1 - 0.11 13.1 0.8 5.9 7.6 0.1 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix domain HI0933_like PF03486.14 KXH56371.1 - 0.13 10.9 0.2 1.1 7.8 0.1 2.0 2 0 0 2 2 2 0 HI0933-like protein Glyoxalase PF00903.25 KXH56375.1 - 4e-09 36.7 0.0 5.5e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily ATP-synt_J PF04911.12 KXH56375.1 - 0.0079 15.8 0.2 0.019 14.5 0.0 1.7 2 0 0 2 2 2 1 ATP synthase j chain PAP2 PF01569.21 KXH56376.1 - 8.2e-27 93.6 2.5 8.2e-27 93.6 2.5 2.2 2 0 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.6 KXH56376.1 - 0.35 11.4 8.7 0.062 13.8 3.6 2.4 2 1 0 2 2 2 0 PAP2 superfamily C-terminal Pectate_lyase PF03211.13 KXH56377.1 - 2.5e-67 226.3 8.5 4.4e-67 225.6 8.5 1.3 1 0 0 1 1 1 1 Pectate lyase AF-4 PF05110.13 KXH56377.1 - 0.55 8.2 13.0 0.77 7.8 13.0 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DIM PF08194.12 KXH56377.1 - 3.7 7.8 9.5 0.69 10.2 0.4 3.0 3 0 0 3 3 3 0 DIM protein Coilin_N PF15862.5 KXH56377.1 - 5.8 6.7 10.1 8.8 6.1 10.1 1.2 1 0 0 1 1 1 0 Coilin N-terminus CFEM PF05730.11 KXH56378.1 - 1.1e-05 25.4 2.1 2e-05 24.6 2.1 1.5 1 0 0 1 1 1 1 CFEM domain EVC2_like PF12297.8 KXH56379.1 - 0.01 14.5 5.5 0.026 13.2 5.6 1.5 2 0 0 2 2 2 0 Ellis van Creveld protein 2 like protein DUF3323 PF11796.8 KXH56379.1 - 0.2 11.5 1.9 0.45 10.4 1.9 1.5 1 0 0 1 1 1 0 Protein of unknown function N-terminus (DUF3323) PhoR PF11808.8 KXH56380.1 - 0.07 13.6 0.2 0.11 13.0 0.2 1.2 1 0 0 1 1 1 0 Phosphate regulon sensor protein PhoR DEC-1_N PF04625.13 KXH56380.1 - 0.24 10.4 3.9 0.27 10.2 3.9 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region DUF2946 PF11162.8 KXH56380.1 - 9.5 6.9 11.5 0.098 13.3 1.8 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2946) NUDIX PF00293.28 KXH56381.1 - 5.2e-16 58.9 0.2 7.3e-16 58.4 0.2 1.2 1 0 0 1 1 1 1 NUDIX domain Fungal_trans PF04082.18 KXH56382.1 - 2.2e-19 69.6 0.0 3.8e-19 68.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH56382.1 - 9e-09 35.3 10.8 1.7e-08 34.4 10.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_76 PF03663.14 KXH56383.1 - 3.5e-132 441.4 16.1 4.1e-132 441.1 16.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 KXH56383.1 - 0.018 14.1 0.1 0.018 14.1 0.1 2.7 2 1 1 3 3 3 0 Glycosyl Hydrolase Family 88 p450 PF00067.22 KXH56384.1 - 1.6e-76 257.9 0.0 1.9e-76 257.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF4735 PF15882.5 KXH56385.1 - 0.088 12.2 0.7 0.12 11.8 0.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4735) DUF1347 PF07079.11 KXH56385.1 - 0.11 11.1 0.1 0.14 10.7 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1347) MFS_1 PF07690.16 KXH56387.1 - 4e-10 39.2 62.5 1.1e-07 31.1 32.0 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KXH56387.1 - 1.3e-05 23.9 19.4 2.1e-05 23.2 19.4 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) SnoaL_2 PF12680.7 KXH56388.1 - 0.00048 20.7 0.0 0.00078 20.1 0.0 1.3 1 1 0 1 1 1 1 SnoaL-like domain EF-hand_1 PF00036.32 KXH56388.1 - 0.074 12.6 0.0 0.43 10.2 0.0 2.1 2 0 0 2 2 2 0 EF hand HET PF06985.11 KXH56389.1 - 6.4e-21 75.2 0.0 2.2e-20 73.5 0.0 2.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) 2-Hacid_dh_C PF02826.19 KXH56390.1 - 2.7e-43 147.4 0.0 1.4e-28 99.4 0.0 2.1 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 KXH56390.1 - 0.15 12.0 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PhyH PF05721.13 KXH56391.1 - 1.1e-09 38.9 0.1 1.7e-09 38.2 0.1 1.4 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 KXH56391.1 - 4.5e-06 25.7 0.0 0.00024 20.0 0.1 2.7 2 1 0 2 2 2 1 Protein of unknown function (DUF1479) 2OG-FeII_Oxy_3 PF13640.6 KXH56391.1 - 0.028 15.3 0.0 0.058 14.3 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.16 KXH56392.1 - 9.9e-12 44.4 28.2 9.9e-12 44.4 28.2 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 KXH56392.1 - 7.5e-08 32.2 6.1 7.5e-08 32.2 6.1 2.6 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 Sugar_tr PF00083.24 KXH56392.1 - 0.00015 20.8 21.7 0.0086 15.0 7.7 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KXH56393.1 - 7.8e-21 74.4 41.6 4.4e-12 45.6 19.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 KXH56393.1 - 0.042 12.2 17.9 0.071 11.5 3.2 2.1 2 0 0 2 2 2 0 Transmembrane secretion effector MFS_4 PF06779.14 KXH56393.1 - 1 8.6 22.2 20 4.4 22.2 2.5 1 1 0 1 1 1 0 Uncharacterised MFS-type transporter YbfB DUF2730 PF10805.8 KXH56395.1 - 0.12 12.5 2.0 0.24 11.5 2.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) Fmp27_WPPW PF10359.9 KXH56395.1 - 1.2 7.9 6.4 1.7 7.4 6.4 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Enkurin PF13864.6 KXH56395.1 - 1.6 9.2 7.3 1.1 9.7 4.8 2.0 2 0 0 2 2 2 0 Calmodulin-binding ABC_tran_Xtn PF12848.7 KXH56395.1 - 1.7 8.7 7.2 2.7 8.1 7.2 1.4 1 0 0 1 1 1 0 ABC transporter bZIP_1 PF00170.21 KXH56395.1 - 5.4 7.2 13.9 27 5.0 13.9 2.1 1 1 0 1 1 1 0 bZIP transcription factor Tannase PF07519.11 KXH56396.1 - 8.8e-95 318.3 0.0 9.8e-95 318.2 0.0 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase MFS_1 PF07690.16 KXH56397.1 - 1.3e-29 103.3 33.3 1.3e-29 103.3 33.3 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily UNC-79 PF14776.6 KXH56398.1 - 0.062 12.1 0.3 0.062 12.1 0.3 1.6 2 0 0 2 2 2 0 Cation-channel complex subunit UNC-79 Lipase_GDSL_2 PF13472.6 KXH56399.1 - 6.6e-16 59.2 0.7 1.2e-15 58.4 0.7 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KXH56399.1 - 2.5e-09 37.4 0.0 5.7e-09 36.2 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase LPP PF04728.13 KXH56399.1 - 0.068 13.6 0.0 0.18 12.2 0.0 1.7 1 0 0 1 1 1 0 Lipoprotein leucine-zipper HPS3_C PF14763.6 KXH56399.1 - 0.13 11.6 0.0 0.18 11.1 0.0 1.1 1 0 0 1 1 1 0 Hermansky-Pudlak syndrome 3, C-terminal DAO PF01266.24 KXH56400.1 - 6.4e-31 108.2 0.0 7.6e-31 108.0 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase SBP_bac_3 PF00497.20 KXH56401.1 - 1.8e-28 99.5 0.1 4.2e-28 98.3 0.1 1.6 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Methyltransf_23 PF13489.6 KXH56403.1 - 2e-21 76.5 0.0 4.1e-21 75.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH56403.1 - 3.5e-12 46.9 0.0 1.4e-11 44.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH56403.1 - 2.4e-10 40.4 0.0 5.8e-05 22.9 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 KXH56403.1 - 9.1e-08 32.7 0.0 2.1e-07 31.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH56403.1 - 4.9e-07 30.4 0.0 7.4e-06 26.6 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXH56403.1 - 0.00076 19.1 0.0 0.0018 17.8 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain PrmA PF06325.13 KXH56403.1 - 0.0095 15.4 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.19 KXH56403.1 - 0.011 15.8 0.0 0.058 13.5 0.0 2.0 2 0 0 2 2 2 0 FtsJ-like methyltransferase Ubie_methyltran PF01209.18 KXH56403.1 - 0.016 14.6 0.0 0.18 11.1 0.0 2.0 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.9 KXH56403.1 - 0.03 14.1 0.0 0.051 13.3 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_4 PF02390.17 KXH56403.1 - 0.057 12.9 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase FAD_binding_4 PF01565.23 KXH56404.1 - 5.8e-08 32.6 1.0 9.7e-08 31.8 1.0 1.4 1 0 0 1 1 1 1 FAD binding domain ALO PF04030.14 KXH56404.1 - 0.078 12.8 0.1 0.2 11.5 0.0 1.7 2 0 0 2 2 2 0 D-arabinono-1,4-lactone oxidase BNR PF02012.20 KXH56405.1 - 6.9e-11 40.5 11.6 0.72 10.1 0.1 6.0 5 0 0 5 5 5 5 BNR/Asp-box repeat BNR_2 PF13088.6 KXH56405.1 - 2.6e-08 33.5 0.0 0.00075 18.9 0.0 3.0 1 1 1 2 2 2 2 BNR repeat-like domain Sortilin-Vps10 PF15902.5 KXH56405.1 - 4.3e-05 22.5 0.0 1.2 7.9 0.0 3.9 4 0 0 4 4 4 2 Sortilin, neurotensin receptor 3, CHB_HEX_C PF03174.13 KXH56405.1 - 0.0045 17.0 0.0 23 5.0 0.0 3.6 4 0 0 4 4 4 1 Chitobiase/beta-hexosaminidase C-terminal domain Lipase_GDSL_2 PF13472.6 KXH56407.1 - 2.7e-06 27.9 2.2 3.6e-06 27.5 2.1 1.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KXH56407.1 - 0.0003 20.8 0.0 0.00048 20.2 0.0 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase RasGAP_C PF03836.15 KXH56407.1 - 0.21 11.7 0.0 26 5.0 0.0 2.3 2 0 0 2 2 2 0 RasGAP C-terminus Glyco_hydro_6 PF01341.17 KXH56408.1 - 9.2e-100 334.3 1.6 1.1e-99 334.0 1.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 MFS_1 PF07690.16 KXH56409.1 - 2e-17 63.2 40.3 3.7e-14 52.4 18.0 2.3 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH56409.1 - 1.6e-07 30.6 9.7 1.6e-07 30.6 9.7 2.8 3 1 0 3 3 3 1 Sugar (and other) transporter GRDP-like PF07173.12 KXH56410.1 - 5e-15 56.4 0.4 2.5e-11 44.4 0.0 3.2 3 0 0 3 3 3 2 Glycine-rich domain-containing protein-like TGT PF01702.18 KXH56410.1 - 0.23 10.6 0.8 2.2 7.3 0.3 2.4 2 0 0 2 2 2 0 Queuine tRNA-ribosyltransferase Prok-E2_D PF14460.6 KXH56411.1 - 0.034 13.8 0.0 0.059 13.1 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family D Sec15 PF04091.12 KXH56411.1 - 0.043 13.2 0.2 0.07 12.5 0.2 1.2 1 0 0 1 1 1 0 Exocyst complex subunit Sec15-like NUDIX PF00293.28 KXH56412.1 - 5.4e-08 32.9 0.0 1.7e-07 31.4 0.0 2.0 1 1 0 1 1 1 1 NUDIX domain Slx4 PF09494.10 KXH56413.1 - 2.8e-22 78.4 0.0 6.5e-22 77.2 0.0 1.6 2 0 0 2 2 2 1 Slx4 endonuclease AT_hook PF02178.19 KXH56413.1 - 0.025 14.4 25.7 0.036 13.9 3.9 4.7 3 0 0 3 3 3 0 AT hook motif Ribosomal_S21e PF01249.18 KXH56414.1 - 1.2e-40 137.4 0.1 1.4e-40 137.3 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e Glyco_hydro2_C5 PF18565.1 KXH56414.1 - 0.024 14.4 0.0 0.03 14.2 0.0 1.2 1 0 0 1 1 1 0 Glycoside hydrolase family 2 C-terminal domain 5 Haem_oxygenas_2 PF14518.6 KXH56414.1 - 0.1 12.4 0.0 0.1 12.3 0.0 1.1 1 0 0 1 1 1 0 Iron-containing redox enzyme MFS_1 PF07690.16 KXH56415.1 - 3.9e-33 114.9 31.0 4.7e-33 114.6 31.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 KXH56415.1 - 1e-05 25.1 6.2 1e-05 25.1 6.2 2.2 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB zf-C2H2_4 PF13894.6 KXH56451.1 - 3.3e-06 27.4 15.6 0.0032 18.2 4.3 2.9 1 1 1 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KXH56451.1 - 1.5e-05 25.2 21.3 0.0062 16.9 6.6 3.2 2 1 1 3 3 3 2 Zinc finger, C2H2 type zf-BED PF02892.15 KXH56451.1 - 0.0037 17.2 14.0 0.3 11.1 4.6 2.5 1 1 1 2 2 2 2 BED zinc finger zf-C2HC_2 PF13913.6 KXH56451.1 - 0.014 15.3 6.0 0.014 15.3 6.0 3.2 4 0 0 4 4 4 0 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.8 KXH56451.1 - 0.024 14.9 7.7 0.11 12.8 0.3 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KXH56451.1 - 0.03 14.3 9.1 0.084 12.9 0.8 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2HE PF16278.5 KXH56451.1 - 0.037 14.5 9.9 0.2 12.1 1.1 2.6 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger HypA PF01155.19 KXH56451.1 - 0.11 12.6 2.4 0.27 11.2 2.4 1.7 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-H2C2_2 PF13465.6 KXH56451.1 - 0.15 12.6 9.9 1 9.9 0.1 3.4 3 0 0 3 3 3 0 Zinc-finger double domain FYVE PF01363.21 KXH56451.1 - 0.15 12.2 9.5 0.17 12.1 7.2 2.3 1 1 1 2 2 2 0 FYVE zinc finger zinc_ribbon_6 PF14599.6 KXH56451.1 - 0.23 11.5 4.4 0.62 10.1 2.8 2.4 2 1 0 2 2 2 0 Zinc-ribbon zinc_ribbon_4 PF13717.6 KXH56451.1 - 0.28 11.1 3.4 0.86 9.6 3.4 1.9 1 1 0 1 1 1 0 zinc-ribbon domain zf-met PF12874.7 KXH56451.1 - 0.35 11.3 7.0 3.9 8.0 0.2 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type PyrI_C PF02748.15 KXH56451.1 - 0.37 10.7 4.0 1.3 9.0 1.0 2.3 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-LYAR PF08790.11 KXH56451.1 - 1.3 9.0 5.6 9.4 6.2 0.8 2.5 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger Zn_ribbon_SprT PF17283.2 KXH56451.1 - 3.3 7.7 15.0 3.6 7.6 7.0 2.7 2 0 0 2 2 2 0 SprT-like zinc ribbon domain EST1_DNA_bind PF10373.9 KXH56453.1 - 1.5e-15 57.4 0.0 3.3e-15 56.3 0.0 1.5 1 1 0 1 1 1 1 Est1 DNA/RNA binding domain DUF2427 PF10348.9 KXH56453.1 - 0.14 12.0 0.1 0.3 10.9 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2427) CCT PF06203.14 KXH56526.1 - 0.7 10.0 6.3 8 6.6 0.4 2.6 2 0 0 2 2 2 0 CCT motif Glyco_hydro_31 PF01055.26 KXH56606.1 - 6.2e-87 292.6 0.8 7.8e-87 292.3 0.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 KXH56606.1 - 7.2e-13 48.7 0.1 1.4e-11 44.5 0.0 3.0 2 1 1 3 3 3 1 Galactose mutarotase-like CN_hydrolase PF00795.22 KXH56608.1 - 1.4e-37 129.5 0.0 1.7e-37 129.2 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Peptidase_S10 PF00450.22 KXH56609.1 - 1.8e-102 343.9 3.1 2.1e-102 343.7 3.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase BetaGal_dom4_5 PF13364.6 KXH56609.1 - 0.014 15.9 0.3 0.048 14.2 0.1 2.0 2 0 0 2 2 2 0 Beta-galactosidase jelly roll domain Sugar_tr PF00083.24 KXH56610.1 - 7.4e-69 232.7 20.0 9e-69 232.5 20.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH56610.1 - 2.9e-11 42.9 18.3 2.9e-11 42.9 18.3 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KXH56610.1 - 5.9e-05 21.7 1.5 0.00012 20.7 0.5 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Folate_carrier PF01770.18 KXH56610.1 - 0.00065 18.5 2.9 0.00074 18.4 1.7 1.6 2 0 0 2 2 2 1 Reduced folate carrier DUF1304 PF06993.12 KXH56610.1 - 0.5 10.4 7.4 0.37 10.8 1.5 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1304) Phage_holin_3_2 PF04550.12 KXH56610.1 - 0.56 10.8 4.1 0.24 11.9 1.4 1.8 2 0 0 2 2 2 0 Phage holin family 2 EpsG PF14897.6 KXH56610.1 - 0.65 9.2 14.5 0.035 13.4 7.1 2.4 2 1 1 3 3 3 0 EpsG family Dynamin_N PF00350.23 KXH56611.1 - 1.7e-32 112.8 0.1 2.7e-32 112.1 0.1 1.4 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 KXH56611.1 - 1.5e-18 67.0 0.0 1.2e-16 60.7 0.0 2.3 2 0 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.23 KXH56611.1 - 2.2e-06 27.8 0.1 2e-05 24.6 0.1 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase GED PF02212.18 KXH56611.1 - 0.0038 17.3 1.7 0.0071 16.5 0.5 2.0 2 0 0 2 2 2 1 Dynamin GTPase effector domain AAA_23 PF13476.6 KXH56611.1 - 0.0061 17.1 0.1 0.04 14.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 KXH56611.1 - 0.014 15.2 0.1 0.032 14.0 0.0 1.6 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system FeoB_N PF02421.18 KXH56611.1 - 0.014 14.9 0.0 1.8 8.1 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_15 PF13175.6 KXH56611.1 - 0.025 14.3 0.0 0.062 13.0 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain Roc PF08477.13 KXH56611.1 - 0.063 13.5 0.0 0.88 9.8 0.0 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase SMC_N PF02463.19 KXH56611.1 - 0.1 12.0 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KXH56611.1 - 0.11 12.3 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Cation_ATPase_C PF00689.21 KXH56612.1 - 8.8e-40 136.4 5.7 8.8e-40 136.4 5.7 3.1 3 0 0 3 3 3 2 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KXH56612.1 - 1.4e-37 128.9 1.1 1.4e-37 128.9 1.1 2.4 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 KXH56612.1 - 1.7e-19 71.0 0.3 1.6e-08 35.1 0.0 3.8 2 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KXH56612.1 - 1.5e-18 66.7 0.0 2.8e-18 65.8 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KXH56612.1 - 6.3e-12 45.0 0.0 1.4e-11 43.9 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KXH56612.1 - 0.0013 18.6 0.4 0.0021 17.9 0.4 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KXH56612.1 - 0.018 15.4 0.1 0.8 10.1 0.1 2.7 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Tmemb_18A PF09771.9 KXH56612.1 - 2.7 8.4 4.5 1.2 9.5 1.3 2.1 2 0 0 2 2 2 0 Transmembrane protein 188 Phage_holin_3_6 PF07332.11 KXH56612.1 - 5.8 7.0 11.6 9.8 6.3 5.2 3.0 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III DUF1933 PF09147.10 KXH56615.1 - 0.017 14.8 0.0 0.052 13.2 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1933) PalH PF08733.10 KXH56616.1 - 0.026 13.6 0.0 0.038 13.0 0.0 1.2 1 0 0 1 1 1 0 PalH/RIM21 DUF2663 PF10864.8 KXH56616.1 - 0.034 14.6 0.0 0.056 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2663) G0-G1_switch_2 PF15103.6 KXH56617.1 - 0.002 18.5 1.2 0.52 10.8 0.1 3.2 2 1 1 3 3 3 1 G0/G1 switch protein 2 Mucin PF01456.17 KXH56617.1 - 0.005 16.8 6.2 0.005 16.8 4.9 1.7 2 0 0 2 2 2 1 Mucin-like glycoprotein FAM176 PF14851.6 KXH56617.1 - 0.007 16.0 1.1 1.3 8.7 0.4 2.4 2 0 0 2 2 2 1 FAM176 family Frizzled PF01534.17 KXH56617.1 - 0.01 14.9 0.0 0.022 13.8 0.0 1.5 1 0 0 1 1 1 0 Frizzled/Smoothened family membrane region Oxidored_q3 PF00499.20 KXH56617.1 - 0.013 15.2 0.0 2.5 7.8 0.0 2.6 2 1 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 CAML PF14963.6 KXH56617.1 - 0.018 15.1 0.7 0.032 14.3 0.7 1.4 1 1 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand EVI2A PF05399.11 KXH56617.1 - 0.025 14.2 3.8 0.051 13.2 3.8 1.4 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) FTR1 PF03239.14 KXH56617.1 - 0.036 13.2 0.6 4.9 6.2 0.0 2.6 2 1 1 3 3 3 0 Iron permease FTR1 family Kei1 PF08552.11 KXH56617.1 - 0.037 13.9 0.4 0.53 10.1 0.1 2.4 2 0 0 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 Presenilin PF01080.17 KXH56617.1 - 0.048 12.4 1.2 0.5 9.1 0.7 2.1 2 0 0 2 2 2 0 Presenilin SARAF PF06682.12 KXH56617.1 - 0.051 13.2 1.8 0.72 9.4 0.2 2.3 2 1 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis SpoIIIAH PF12685.7 KXH56617.1 - 0.065 13.1 9.5 1.5 8.6 6.0 2.2 2 0 0 2 2 2 0 SpoIIIAH-like protein Mucin15 PF15672.5 KXH56617.1 - 0.076 12.5 7.4 3.6 7.0 0.0 2.2 2 0 0 2 2 2 0 Cell-membrane associated Mucin15 Collectrin PF16959.5 KXH56617.1 - 0.092 12.5 0.0 3.1 7.5 0.0 2.5 2 0 0 2 2 2 0 Renal amino acid transporter UPF0239 PF06783.11 KXH56617.1 - 0.13 12.5 2.5 4.8 7.4 0.0 3.0 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0239) DUF4834 PF16118.5 KXH56617.1 - 0.16 12.9 5.1 2.3 9.2 0.8 2.8 2 2 0 2 2 2 0 Domain of unknown function (DUF4834) CPSF100_C PF13299.6 KXH56617.1 - 0.16 12.1 3.9 4.2 7.5 3.8 2.3 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal DUF4027 PF13219.6 KXH56617.1 - 0.29 11.0 3.1 0.22 11.4 1.1 1.9 2 0 0 2 2 1 0 Protein of unknown function (DUF4027) DUF4064 PF13273.6 KXH56617.1 - 0.34 11.2 6.8 16 5.9 0.1 4.0 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) FixS PF03597.15 KXH56617.1 - 1.1 9.1 0.0 1.1 9.1 0.0 2.7 3 0 0 3 3 2 0 Cytochrome oxidase maturation protein cbb3-type DUF2371 PF10177.9 KXH56617.1 - 2.1 8.5 4.7 45 4.2 0.1 3.3 2 2 0 2 2 2 0 Uncharacterised conserved protein (DUF2371) Phage_Gp23 PF10669.9 KXH56617.1 - 2.7 8.3 5.9 8.1 6.8 0.4 2.9 2 1 1 3 3 3 0 Protein gp23 (Bacteriophage A118) ORC_WH_C PF18137.1 KXH56617.1 - 3.1 7.9 5.9 2.9 7.9 0.1 2.3 1 1 0 2 2 2 0 Origin recognition complex winged helix C-terminal DUF3335 PF11814.8 KXH56618.1 - 0.085 12.3 0.1 0.14 11.6 0.0 1.3 1 1 0 1 1 1 0 Peptidase_C39 like family MU117 PF15474.6 KXH56619.1 - 1e-18 68.0 8.8 1.3e-18 67.6 8.8 1.1 1 0 0 1 1 1 1 Meiotically up-regulated gene family Kp4 PF09044.10 KXH56619.1 - 0.099 12.7 7.3 0.19 11.8 7.3 1.4 1 1 0 1 1 1 0 Kp4 Pkinase PF00069.25 KXH56620.1 - 2.5e-35 122.1 0.0 3.5e-35 121.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXH56620.1 - 2.2e-19 69.8 0.0 3.4e-19 69.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXH56620.1 - 0.00037 19.9 0.0 0.033 13.5 0.0 2.3 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 KXH56620.1 - 0.0055 16.7 0.0 0.02 14.8 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family SUR7 PF06687.12 KXH56622.1 - 5e-15 55.7 2.5 6.6e-15 55.3 2.5 1.1 1 0 0 1 1 1 1 SUR7/PalI family DUF2070 PF09843.9 KXH56622.1 - 1.1 7.5 14.5 1.7 6.9 14.5 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) BPL_LplA_LipB PF03099.19 KXH56627.1 - 8.2e-05 22.5 0.0 0.00017 21.5 0.0 1.5 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Phytase PF02333.15 KXH56627.1 - 0.034 13.1 0.0 0.051 12.5 0.0 1.1 1 0 0 1 1 1 0 Phytase SUR7 PF06687.12 KXH56628.1 - 1.5e-30 106.4 10.0 2.2e-30 105.9 10.0 1.2 1 0 0 1 1 1 1 SUR7/PalI family Trp_oprn_chp PF09534.10 KXH56628.1 - 0.00015 21.6 2.6 0.00015 21.6 2.6 1.5 2 0 0 2 2 2 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Amastin PF07344.11 KXH56628.1 - 1.1 9.1 16.7 0.11 12.4 12.3 1.5 2 0 0 2 2 2 0 Amastin surface glycoprotein Clc-like PF07062.12 KXH56628.1 - 2.7 7.4 9.4 0.25 10.8 5.0 1.5 2 0 0 2 2 2 0 Clc-like Pkinase PF00069.25 KXH56629.1 - 1.2e-53 182.2 0.0 1.1e-50 172.5 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXH56629.1 - 1.5e-29 103.1 0.0 3.4e-28 98.6 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Seadorna_VP7 PF07387.11 KXH56629.1 - 0.00047 19.3 0.1 0.0009 18.4 0.1 1.4 1 0 0 1 1 1 1 Seadornavirus VP7 Kinase-like PF14531.6 KXH56629.1 - 0.00078 18.8 0.0 0.0011 18.3 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KXH56629.1 - 0.045 12.7 0.0 0.064 12.2 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 KXH56629.1 - 0.17 10.6 0.0 0.25 10.1 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Presenilin PF01080.17 KXH56630.1 - 6.5 5.4 6.2 7.1 5.3 6.2 1.0 1 0 0 1 1 1 0 Presenilin Mem_trans PF03547.18 KXH56631.1 - 2.7e-46 157.7 6.3 3e-45 154.3 6.3 1.9 1 1 0 1 1 1 1 Membrane transport protein DUF1634 PF07843.11 KXH56631.1 - 3.1 7.9 6.2 0.56 10.3 0.2 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1634) RRM_1 PF00076.22 KXH56632.1 - 3.7e-13 49.1 0.0 2.1e-05 24.2 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4150 PF13665.6 KXH56633.1 - 0.025 14.7 1.0 0.039 14.1 1.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4150) Fasciclin PF02469.22 KXH56634.1 - 8.2e-44 148.9 0.1 5.2e-27 94.6 0.0 2.2 2 0 0 2 2 2 2 Fasciclin domain Glyco_hydro_16 PF00722.21 KXH56635.1 - 6.5e-15 55.0 1.5 1.1e-14 54.3 1.5 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 TaqI_C PF12950.7 KXH56635.1 - 0.096 12.8 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 TaqI-like C-terminal specificity domain Glyco_trans_2_3 PF13632.6 KXH56636.1 - 2.3e-52 177.8 2.7 2.3e-52 177.8 2.7 2.1 2 1 1 3 3 3 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 KXH56636.1 - 2.8e-06 27.2 0.0 6.8e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 KXH56636.1 - 0.0033 16.9 0.0 0.0067 15.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 21 ABC_tran PF00005.27 KXH56637.1 - 1.1e-47 162.0 0.1 7.3e-26 91.3 0.0 4.1 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KXH56637.1 - 1.5e-14 54.5 1.7 5.2e-05 23.2 0.9 4.7 3 1 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KXH56637.1 - 7.7e-13 48.4 0.1 8.6e-05 22.1 0.0 4.2 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KXH56637.1 - 1.8e-09 38.4 1.0 0.00023 21.8 0.1 3.2 3 0 0 3 3 3 2 AAA domain Chromo PF00385.24 KXH56637.1 - 5.6e-08 32.6 0.7 1.4e-07 31.3 0.7 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain MMR_HSR1 PF01926.23 KXH56637.1 - 2.1e-07 31.0 0.0 0.0044 17.1 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KXH56637.1 - 4e-07 30.1 0.0 0.0034 17.3 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 KXH56637.1 - 4.8e-07 29.4 0.4 0.0088 15.8 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_28 PF13521.6 KXH56637.1 - 3e-05 24.3 0.0 0.009 16.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KXH56637.1 - 4.9e-05 23.6 0.1 0.64 10.3 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_18 PF13238.6 KXH56637.1 - 0.0002 21.9 0.0 0.15 12.6 0.0 3.1 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 KXH56637.1 - 0.00035 20.8 0.9 0.63 10.1 0.1 4.0 4 0 0 4 4 4 1 Helicase HerA, central domain RNA_helicase PF00910.22 KXH56637.1 - 0.0009 19.6 0.0 2.5 8.5 0.0 2.6 2 0 0 2 2 2 2 RNA helicase NACHT PF05729.12 KXH56637.1 - 0.00091 19.2 0.2 0.84 9.5 0.0 3.0 3 0 0 3 3 3 1 NACHT domain CLASP_N PF12348.8 KXH56637.1 - 0.00093 18.8 0.0 0.0039 16.8 0.0 2.0 2 0 0 2 2 2 1 CLASP N terminal MeaB PF03308.16 KXH56637.1 - 0.0013 17.7 0.4 0.31 10.0 0.1 2.5 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB ALF PF03752.13 KXH56637.1 - 0.0014 18.5 0.3 1.4 8.9 0.1 3.1 2 0 0 2 2 2 1 Short repeats of unknown function AAA_15 PF13175.6 KXH56637.1 - 0.0016 18.2 4.9 0.39 10.4 1.4 3.1 3 1 0 3 3 2 2 AAA ATPase domain Septin PF00735.18 KXH56637.1 - 0.0031 16.8 0.0 0.74 9.0 0.0 2.5 2 0 0 2 2 2 1 Septin AAA_33 PF13671.6 KXH56637.1 - 0.0039 17.3 1.2 4.3 7.5 0.0 3.4 3 0 0 3 3 2 1 AAA domain AAA_30 PF13604.6 KXH56637.1 - 0.0043 16.8 0.2 2 8.1 0.1 2.9 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 KXH56637.1 - 0.0056 15.9 0.0 1.6 7.8 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_24 PF13479.6 KXH56637.1 - 0.0083 15.9 0.3 0.8 9.4 0.1 2.6 2 0 0 2 2 2 1 AAA domain AAA_13 PF13166.6 KXH56637.1 - 0.0084 14.8 0.4 0.9 8.1 0.0 2.6 3 0 0 3 3 2 1 AAA domain AAA_16 PF13191.6 KXH56637.1 - 0.01 16.2 0.5 4.7 7.6 0.0 3.6 3 1 0 3 3 3 0 AAA ATPase domain AAA PF00004.29 KXH56637.1 - 0.011 16.2 0.0 5.5 7.4 0.0 3.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.9 KXH56637.1 - 0.016 14.9 0.0 0.85 9.4 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_14 PF13173.6 KXH56637.1 - 0.017 15.2 0.0 6.5 6.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_27 PF13514.6 KXH56637.1 - 0.019 14.6 0.7 7.3 6.1 0.0 3.0 3 0 0 3 3 3 0 AAA domain Dynamin_N PF00350.23 KXH56637.1 - 0.042 13.9 0.0 0.94 9.5 0.0 2.8 2 0 0 2 2 2 0 Dynamin family Roc PF08477.13 KXH56637.1 - 0.056 13.7 0.0 12 6.2 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase TsaE PF02367.17 KXH56637.1 - 0.059 13.4 0.4 19 5.3 0.1 2.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NB-ARC PF00931.22 KXH56637.1 - 0.06 12.5 0.1 3.7 6.6 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain CLP1_P PF16575.5 KXH56637.1 - 0.094 12.5 0.4 22 4.8 0.0 3.3 3 0 0 3 3 3 0 mRNA cleavage and polyadenylation factor CLP1 P-loop NTPase_1 PF03266.15 KXH56637.1 - 0.099 12.5 0.3 20 5.0 0.3 3.1 2 0 0 2 2 2 0 NTPase HEAT PF02985.22 KXH56637.1 - 0.11 12.8 1.6 26 5.4 0.1 4.9 5 0 0 5 5 3 0 HEAT repeat SR-25 PF10500.9 KXH56637.1 - 0.14 11.7 4.9 0.29 10.7 4.9 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Glyco_hydro_3_C PF01915.22 KXH56638.1 - 7e-47 160.0 0.0 1.6e-46 158.9 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KXH56638.1 - 2.5e-42 145.4 0.0 4e-42 144.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KXH56638.1 - 1.4e-22 79.5 0.1 2.9e-22 78.5 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF1652 PF07865.11 KXH56639.1 - 0.051 13.4 0.0 0.098 12.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1652) MFS_1 PF07690.16 KXH56640.1 - 3.2e-38 131.6 10.4 5.4e-38 130.8 10.4 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH56640.1 - 2.5e-08 33.2 7.6 2.5e-08 33.2 7.6 3.2 2 2 0 3 3 3 1 Sugar (and other) transporter MFS_3 PF05977.13 KXH56640.1 - 1.7e-05 23.4 9.4 0.00032 19.2 3.5 2.3 2 0 0 2 2 2 2 Transmembrane secretion effector MFS_1_like PF12832.7 KXH56640.1 - 0.91 8.3 10.6 1.6 7.5 5.1 2.4 1 1 1 2 2 2 0 MFS_1 like family DUF4131 PF13567.6 KXH56640.1 - 1.5 8.4 13.3 0.17 11.5 0.4 3.9 3 1 1 4 4 4 0 Domain of unknown function (DUF4131) PBP1_TM PF14812.6 KXH56640.1 - 4.4 7.7 5.9 3 8.3 2.6 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Pox_Ag35 PF03286.14 KXH56640.1 - 4.4 7.0 4.9 5.8 6.6 1.3 2.2 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Glyco_hydro_88 PF07470.13 KXH56641.1 - 3.7e-91 305.8 1.0 4.2e-91 305.6 1.0 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Glyco_hydro_76 PF03663.14 KXH56641.1 - 0.029 13.9 1.0 0.11 11.9 1.1 2.0 1 1 1 2 2 2 0 Glycosyl hydrolase family 76 MFS_1 PF07690.16 KXH56642.1 - 1.6e-36 126.0 19.5 2.4e-36 125.4 19.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Trp_oprn_chp PF09534.10 KXH56642.1 - 0.086 12.6 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF3827 PF12877.7 KXH56642.1 - 0.16 10.3 0.3 0.3 9.4 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) DUF1003 PF06210.11 KXH56642.1 - 0.6 10.2 0.1 0.6 10.2 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1003) Epimerase PF01370.21 KXH56643.1 - 1.4e-17 64.0 0.1 2.3e-17 63.3 0.1 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KXH56643.1 - 1.8e-09 37.1 0.1 2.3e-09 36.7 0.1 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 KXH56643.1 - 1e-08 35.3 0.7 3.6e-08 33.5 0.7 1.8 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KXH56643.1 - 2.6e-08 33.7 0.1 4.2e-08 33.0 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family GDP_Man_Dehyd PF16363.5 KXH56643.1 - 2.1e-06 27.4 0.0 0.0011 18.5 0.0 2.3 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KXH56643.1 - 2.9e-05 23.2 0.1 0.00019 20.5 0.0 1.9 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KXH56643.1 - 0.0077 15.4 0.1 0.14 11.2 0.1 2.1 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 KXH56643.1 - 0.0092 15.2 0.0 3.3 6.8 0.0 2.2 1 1 1 2 2 2 2 Male sterility protein SNAP PF14938.6 KXH56643.1 - 0.016 14.7 0.1 0.024 14.1 0.1 1.2 1 0 0 1 1 1 0 Soluble NSF attachment protein, SNAP DapB_N PF01113.20 KXH56643.1 - 0.044 13.9 0.0 0.14 12.3 0.0 1.8 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.24 KXH56643.1 - 0.13 12.7 0.2 1.3 9.5 0.0 2.3 2 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.25 KXH56644.1 - 5.8e-24 84.6 0.3 1.3e-21 76.9 0.2 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXH56644.1 - 1.4e-12 47.7 0.2 2.7e-11 43.5 0.2 2.1 1 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH56644.1 - 8.1e-09 35.6 0.2 1.5e-08 34.8 0.2 1.4 1 0 0 1 1 1 1 KR domain Aldo_ket_red PF00248.21 KXH56645.1 - 1.7e-64 217.9 0.2 2.6e-64 217.3 0.0 1.3 2 0 0 2 2 2 1 Aldo/keto reductase family Peroxidase_2 PF01328.17 KXH56646.1 - 2.3e-40 139.1 0.0 2.8e-40 138.8 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 PSII_Pbs27 PF13326.6 KXH56646.1 - 0.0077 16.6 0.0 0.011 16.0 0.0 1.5 2 0 0 2 2 2 1 Photosystem II Pbs27 NACHT PF05729.12 KXH56647.1 - 1.4e-10 41.3 0.0 3.3e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KXH56647.1 - 1.5e-05 25.4 0.2 0.00014 22.3 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KXH56647.1 - 0.00095 19.5 0.0 0.0032 17.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 KXH56647.1 - 0.0078 16.6 0.0 0.024 15.0 0.0 1.8 1 0 0 1 1 1 1 RNA helicase An_peroxidase PF03098.15 KXH56647.1 - 0.0082 14.8 0.9 1.6 7.2 0.4 2.2 2 0 0 2 2 2 2 Animal haem peroxidase KAP_NTPase PF07693.14 KXH56647.1 - 0.0092 15.3 0.2 0.79 8.9 0.0 2.5 2 1 0 3 3 3 1 KAP family P-loop domain ATPase PF06745.13 KXH56647.1 - 0.011 15.1 0.5 1.1 8.6 0.5 2.2 2 0 0 2 2 2 0 KaiC AAA PF00004.29 KXH56647.1 - 0.025 15.0 0.0 0.25 11.8 0.0 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DNA_pol_B PF00136.21 KXH56647.1 - 0.025 13.3 0.1 0.032 12.9 0.1 1.1 1 0 0 1 1 1 0 DNA polymerase family B ABC_tran PF00005.27 KXH56647.1 - 0.029 14.9 0.1 0.38 11.3 0.0 2.3 2 0 0 2 2 2 0 ABC transporter NB-ARC PF00931.22 KXH56647.1 - 0.062 12.5 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain MMR_HSR1 PF01926.23 KXH56647.1 - 0.081 13.0 0.3 0.55 10.3 0.0 2.3 2 1 0 2 2 2 0 50S ribosome-binding GTPase cobW PF02492.19 KXH56647.1 - 0.15 11.6 0.0 0.36 10.4 0.0 1.7 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Fib_alpha PF08702.10 KXH56647.1 - 0.53 10.5 5.4 1.2 9.3 5.3 1.6 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF87 PF01935.17 KXH56647.1 - 0.6 10.2 3.3 4.5 7.3 0.1 2.7 2 1 0 2 2 2 0 Helicase HerA, central domain DnaI_N PF07319.11 KXH56647.1 - 0.67 10.7 2.8 4.4 8.1 0.0 2.4 1 1 0 2 2 2 0 Primosomal protein DnaI N-terminus zf-MYND PF01753.18 KXH56791.1 - 2.1e-07 30.9 13.8 4e-07 30.0 13.8 1.5 1 0 0 1 1 1 1 MYND finger Rhodanese_C PF12368.8 KXH56791.1 - 0.37 11.2 3.2 0.71 10.3 3.2 1.4 1 0 0 1 1 1 0 Rhodanase C-terminal OTT_1508_deam PF14441.6 KXH56794.1 - 5.2e-18 64.8 0.2 1.1e-17 63.8 0.2 1.5 1 0 0 1 1 1 1 OTT_1508-like deaminase Dehydratase_hem PF13816.6 KXH56795.1 - 3.9e-113 377.9 0.2 4.5e-113 377.7 0.2 1.0 1 0 0 1 1 1 1 Haem-containing dehydratase DUF4188 PF13826.6 KXH56795.1 - 1.2e-05 25.7 0.0 0.18 12.1 0.1 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4188) DUF4400 PF14348.6 KXH56795.1 - 0.19 11.2 0.0 0.31 10.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4400) PRT_C PF08372.10 KXH56796.1 - 0.46 10.2 2.4 0.54 10.0 0.7 1.9 1 1 1 2 2 2 0 Plant phosphoribosyltransferase C-terminal PyrBI_leader PF08052.11 KXH56797.1 - 0.16 12.0 0.0 2.8 8.0 0.0 2.4 2 0 0 2 2 2 0 PyrBI operon leader peptide Tox-SHH PF15652.6 KXH56798.1 - 0.13 13.2 0.1 0.28 12.2 0.1 1.4 1 0 0 1 1 1 0 HNH/Endo VII superfamily toxin with a SHH signature GPI-anchored PF10342.9 KXH56800.1 - 7.1e-17 61.9 2.0 7.1e-17 61.9 2.0 2.2 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family MFS_1 PF07690.16 KXH56801.1 - 3.9e-20 72.1 42.8 5.7e-20 71.5 42.8 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Methyltransf_23 PF13489.6 KXH56801.1 - 1.4e-19 70.6 0.0 2.5e-19 69.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH56801.1 - 2.7e-11 43.5 0.0 9.8e-11 41.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH56801.1 - 3.3e-11 43.7 0.0 8.1e-11 42.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH56801.1 - 4.2e-08 33.7 0.0 1.1e-07 32.4 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH56801.1 - 4.3e-07 30.6 0.0 5e-06 27.2 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 KXH56801.1 - 0.0002 20.8 0.0 0.00034 20.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KXH56801.1 - 0.013 15.1 0.0 0.026 14.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain MFS_3 PF05977.13 KXH56801.1 - 0.014 13.8 1.3 0.025 13.0 1.3 1.4 1 0 0 1 1 1 0 Transmembrane secretion effector FtsJ PF01728.19 KXH56801.1 - 0.014 15.5 0.0 0.029 14.5 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_16 PF10294.9 KXH56801.1 - 0.04 13.7 0.0 0.083 12.6 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase CheR PF01739.18 KXH56801.1 - 0.079 12.4 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain DUF938 PF06080.12 KXH56801.1 - 0.083 12.6 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Met_10 PF02475.16 KXH56801.1 - 0.09 12.5 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein PCMT PF01135.19 KXH56801.1 - 0.15 11.8 0.0 0.36 10.5 0.0 1.6 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) HET PF06985.11 KXH56802.1 - 2.3e-34 118.8 0.2 4.5e-34 117.9 0.2 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Peptidase_C2 PF00648.21 KXH56803.1 - 1.2e-15 57.4 0.0 1.8e-15 56.7 0.0 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease Peptidase_C1 PF00112.23 KXH56803.1 - 0.1 12.7 0.2 0.16 12.0 0.2 1.3 1 0 0 1 1 1 0 Papain family cysteine protease WSC PF01822.19 KXH56804.1 - 2.8e-08 33.8 15.9 9.3e-05 22.5 1.3 3.2 3 1 0 3 3 3 2 WSC domain FXa_inhibition PF14670.6 KXH56804.1 - 4.6 7.6 8.9 2.1 8.7 1.8 2.5 2 0 0 2 2 2 0 Coagulation Factor Xa inhibitory site Ribonuclease_T2 PF00445.18 KXH56805.1 - 0.00093 19.5 0.0 0.0011 19.2 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease T2 family RGI_lyase PF18370.1 KXH56860.1 - 4.2e-19 68.6 0.0 1.2e-18 67.2 0.0 1.8 1 0 0 1 1 1 1 Rhamnogalacturonan I lyases beta-sheet domain VCBS PF13517.6 KXH56860.1 - 4.6e-08 33.5 16.0 0.0098 16.5 0.2 6.3 6 0 0 6 6 6 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella p450 PF00067.22 KXH56861.1 - 1.4e-58 198.8 0.0 1.6e-58 198.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ICL PF00463.21 KXH56862.1 - 3.3e-10 39.1 0.6 2.2e-09 36.4 0.6 1.9 1 1 0 1 1 1 1 Isocitrate lyase family DUF1481 PF07356.12 KXH56862.1 - 0.095 12.5 0.1 0.2 11.4 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1481) Aminotran_1_2 PF00155.21 KXH56863.1 - 1.2e-18 67.4 0.0 1.6e-18 67.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 KXH56863.1 - 0.014 14.2 0.0 0.034 12.9 0.0 1.7 1 1 0 1 1 1 0 Alanine-glyoxylate amino-transferase Peptidase_M18 PF02127.15 KXH56863.1 - 0.23 10.2 0.0 0.35 9.6 0.0 1.1 1 0 0 1 1 1 0 Aminopeptidase I zinc metalloprotease (M18) MFS_1 PF07690.16 KXH56864.1 - 1.6e-32 112.8 17.7 1.6e-32 112.8 17.7 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 KXH56864.1 - 8.4e-05 21.6 0.1 0.00019 20.5 0.1 1.6 1 1 0 1 1 1 1 MFS_1 like family HpcH_HpaI PF03328.14 KXH56865.1 - 3.3e-15 55.8 0.5 9.2e-15 54.4 0.5 1.7 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PK PF00224.21 KXH56865.1 - 0.034 13.0 0.0 0.049 12.5 0.0 1.2 1 0 0 1 1 1 0 Pyruvate kinase, barrel domain Tetraspanin PF00335.20 KXH56866.1 - 3.2e-05 23.8 0.2 5.5e-05 23.0 0.2 1.4 1 1 0 1 1 1 1 Tetraspanin family PI-PLC-X PF00388.19 KXH56867.1 - 1.9e-49 167.0 0.0 2.9e-49 166.4 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 KXH56867.1 - 2.3e-37 127.8 0.0 3.8e-37 127.1 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 KXH56867.1 - 0.012 15.9 0.0 0.028 14.7 0.0 1.6 1 1 0 1 1 1 0 C2 domain ANAPC15 PF15243.6 KXH56867.1 - 2.1 8.8 7.1 36 4.8 5.7 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 AflR PF08493.10 KXH56900.1 - 3.2e-09 36.7 3.1 3.2e-09 36.7 3.1 2.0 2 1 0 2 2 2 1 Aflatoxin regulatory protein Zn_clus PF00172.18 KXH56900.1 - 6.8e-08 32.5 11.6 6.8e-08 32.5 11.6 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ketoacyl-synt PF00109.26 KXH57050.1 - 1.1e-64 218.4 1.4 9.7e-56 189.2 0.3 2.8 3 0 0 3 3 3 2 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KXH57050.1 - 3.2e-39 133.6 0.1 7.3e-39 132.4 0.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.21 KXH57050.1 - 3.2e-25 89.3 0.0 1.6e-24 87.0 0.0 2.0 2 0 0 2 2 2 1 Acyl transferase domain PS-DH PF14765.6 KXH57050.1 - 6.5e-23 81.4 0.1 1.3e-22 80.4 0.1 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Abhydrolase_3 PF07859.13 KXH57050.1 - 2.4e-16 60.2 0.1 2.8e-14 53.5 0.1 2.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KXH57050.1 - 1.9e-10 40.6 0.0 9.6e-07 28.5 0.0 2.9 3 0 0 3 3 3 2 Prolyl oligopeptidase family PP-binding PF00550.25 KXH57050.1 - 4.4e-08 33.4 0.1 1e-07 32.2 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site SAT PF16073.5 KXH57050.1 - 8.8e-08 32.2 0.9 1.4e-05 25.0 0.0 3.4 3 0 0 3 3 3 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Thiolase_N PF00108.23 KXH57050.1 - 6.3e-07 29.0 0.1 1.6e-06 27.7 0.1 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain KAsynt_C_assoc PF16197.5 KXH57050.1 - 1.4e-05 25.5 0.0 3.5e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Abhydrolase_6 PF12697.7 KXH57050.1 - 1.9e-05 25.4 4.2 0.00017 22.3 1.6 3.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family DLH PF01738.18 KXH57050.1 - 0.00037 20.1 0.5 0.007 15.9 0.0 2.6 3 0 0 3 3 3 1 Dienelactone hydrolase family Esterase PF00756.20 KXH57050.1 - 0.0078 15.9 0.0 0.46 10.1 0.0 2.7 2 0 0 2 2 2 1 Putative esterase Abhydrolase_4 PF08386.10 KXH57050.1 - 0.045 13.9 0.0 0.16 12.1 0.0 1.9 1 0 0 1 1 1 0 TAP-like protein Abhydrolase_2 PF02230.16 KXH57050.1 - 0.098 12.4 0.0 0.41 10.4 0.0 2.0 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase adh_short PF00106.25 KXH57051.1 - 1.8e-10 40.6 0.0 3.8e-09 36.3 0.0 2.2 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXH57051.1 - 8.5e-06 25.5 0.0 9.6e-05 22.0 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ketoacyl-synt PF00109.26 KXH57052.1 - 1.5e-69 234.4 0.0 9.1e-69 231.8 0.0 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain SAT PF16073.5 KXH57052.1 - 7e-42 143.8 0.0 7e-42 143.8 0.0 2.6 3 0 0 3 3 3 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Acyl_transf_1 PF00698.21 KXH57052.1 - 4.2e-34 118.5 0.0 8.4e-34 117.5 0.0 1.6 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KXH57052.1 - 7.7e-32 109.8 0.2 2.1e-31 108.4 0.2 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.6 KXH57052.1 - 5.6e-16 58.6 0.0 1.3e-15 57.4 0.0 1.6 1 0 0 1 1 1 1 Polyketide synthase dehydratase PP-binding PF00550.25 KXH57052.1 - 2.7e-08 34.0 0.2 7.5e-08 32.6 0.2 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thioesterase PF00975.20 KXH57052.1 - 9.9e-06 25.8 0.5 4e-05 23.9 0.0 2.1 2 0 0 2 2 2 1 Thioesterase domain Thiolase_N PF00108.23 KXH57052.1 - 0.0012 18.3 0.8 0.0034 16.8 0.9 1.7 2 0 0 2 2 2 1 Thiolase, N-terminal domain KAsynt_C_assoc PF16197.5 KXH57052.1 - 0.0035 17.8 0.0 0.0093 16.4 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Abhydrolase_3 PF07859.13 KXH57052.1 - 0.11 12.4 0.1 0.32 10.8 0.1 1.8 1 0 0 1 1 1 0 alpha/beta hydrolase fold ADH_zinc_N_2 PF13602.6 KXH57053.1 - 1.3e-14 55.4 0.0 2.5e-14 54.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KXH57053.1 - 1.3e-11 44.6 0.0 2.4e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXH57053.1 - 9.3e-05 22.3 0.0 0.00031 20.6 0.0 1.8 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Peptidase_U32 PF01136.19 KXH57053.1 - 0.079 12.1 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 Peptidase family U32 TrkA_N PF02254.18 KXH57053.1 - 0.11 12.8 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain HTH_7 PF02796.15 KXH57053.1 - 0.13 12.4 0.0 0.38 10.9 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase ketoacyl-synt PF00109.26 KXH57054.1 - 2.4e-63 214.1 0.0 5.7e-63 212.8 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.6 KXH57054.1 - 2.8e-53 181.1 0.0 6.3e-53 179.9 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 KXH57054.1 - 2.5e-47 161.1 0.1 6.6e-47 159.7 0.1 1.8 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.21 KXH57054.1 - 2e-43 149.2 0.6 3.9e-43 148.2 0.1 1.8 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KXH57054.1 - 3.9e-36 123.6 0.7 9.4e-36 122.4 0.7 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KXH57054.1 - 2.4e-13 50.5 0.0 1.7e-12 47.8 0.0 2.6 2 1 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension ADH_N PF08240.12 KXH57054.1 - 2.6e-07 30.5 0.1 6.4e-07 29.2 0.1 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 KXH57054.1 - 4e-07 29.7 0.0 1.2e-06 28.1 0.0 1.9 1 0 0 1 1 1 1 short chain dehydrogenase Thiolase_N PF00108.23 KXH57054.1 - 6.3e-06 25.7 0.2 1.9e-05 24.2 0.2 1.8 1 1 0 1 1 1 1 Thiolase, N-terminal domain ADH_zinc_N_2 PF13602.6 KXH57054.1 - 6.6e-06 27.2 0.1 3.7e-05 24.8 0.0 2.4 2 0 0 2 2 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KXH57054.1 - 7.3e-06 26.0 0.1 2.8e-05 24.1 0.1 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PP-binding PF00550.25 KXH57054.1 - 0.00057 20.2 0.0 0.0017 18.7 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short_C2 PF13561.6 KXH57054.1 - 0.0082 15.7 0.0 0.022 14.3 0.0 1.7 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Methyltransf_23 PF13489.6 KXH57054.1 - 0.024 14.5 0.0 0.18 11.6 0.0 2.3 2 1 0 2 2 2 0 Methyltransferase domain Glu_dehyd_C PF16912.5 KXH57054.1 - 0.084 12.3 0.1 0.36 10.3 0.1 2.0 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus Trp_DMAT PF11991.8 KXH57055.1 - 2.5e-62 211.4 0.0 2.9e-62 211.2 0.0 1.0 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase Epimerase PF01370.21 KXH57056.1 - 1.3e-07 31.4 0.0 1.8e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family p450 PF00067.22 KXH57057.1 - 1.6e-60 205.2 0.0 1.6e-37 129.4 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 p450 PF00067.22 KXH57058.1 - 5.3e-64 216.7 0.0 5.9e-64 216.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_3 PF01494.19 KXH57059.1 - 3.3e-46 158.2 0.0 4.8e-46 157.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Thioesterase PF00975.20 KXH57059.1 - 4e-14 53.3 0.0 7.5e-14 52.4 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain PP-binding PF00550.25 KXH57059.1 - 2.3e-06 27.9 0.1 4.7e-06 26.9 0.1 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site HI0933_like PF03486.14 KXH57059.1 - 7.6e-05 21.6 0.1 0.00077 18.3 0.1 2.0 1 1 0 1 1 1 1 HI0933-like protein DAO PF01266.24 KXH57059.1 - 0.00018 21.2 0.4 0.33 10.5 0.3 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXH57059.1 - 0.00052 20.2 0.2 0.0014 18.8 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KXH57059.1 - 0.0024 17.0 0.1 0.0085 15.2 0.1 1.9 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KXH57059.1 - 0.005 16.1 0.2 0.051 12.8 0.2 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Abhydrolase_6 PF12697.7 KXH57059.1 - 0.0064 17.1 0.2 0.018 15.6 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family SE PF08491.10 KXH57059.1 - 0.036 13.1 0.0 0.055 12.5 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase Pyr_redox_3 PF13738.6 KXH57059.1 - 0.047 12.9 0.1 0.13 11.5 0.1 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KXH57059.1 - 0.06 12.6 0.1 0.21 10.8 0.1 1.8 2 1 0 2 2 2 0 Flavin containing amine oxidoreductase Thi4 PF01946.17 KXH57059.1 - 0.065 12.5 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.24 KXH57059.1 - 0.098 11.7 0.6 0.39 9.7 0.6 1.8 1 1 1 2 2 2 0 FAD binding domain Glu_dehyd_C PF16912.5 KXH57059.1 - 0.2 11.1 0.0 0.36 10.3 0.0 1.3 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus DUF4149 PF13664.6 KXH57105.1 - 0.13 12.6 2.7 13 6.1 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4149) RNA_pol_Rpb5_C PF01191.19 KXH57106.1 - 2.4e-32 110.6 0.3 4.1e-32 109.9 0.3 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 KXH57106.1 - 5.2e-26 91.1 0.0 8e-26 90.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.12 KXH57106.1 - 0.05 13.6 0.0 0.5 10.4 0.0 2.1 2 0 0 2 2 2 0 Restriction endonuclease ABC_tran_CTD PF16326.5 KXH57107.1 - 5.8e-05 23.3 4.5 5.8e-05 23.3 4.5 5.7 4 3 3 7 7 7 1 ABC transporter C-terminal domain Occludin_ELL PF07303.13 KXH57107.1 - 0.027 15.2 2.9 0.027 15.2 2.9 5.2 3 2 1 5 5 5 0 Occludin homology domain BAG PF02179.16 KXH57107.1 - 0.058 13.8 0.8 0.058 13.8 0.8 4.3 4 0 0 4 4 4 0 BAG domain CorA PF01544.18 KXH57107.1 - 1.1 8.5 8.1 0.95 8.7 6.3 1.8 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF4239 PF14023.6 KXH57107.1 - 1.3 8.7 8.9 2.4 7.8 1.8 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF4239) Acyl-CoA_dh_M PF02770.19 KXH57119.1 - 3.3e-06 27.2 0.0 5.8e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain CCCAP PF15964.5 KXH57119.1 - 0.1 10.9 0.0 0.13 10.6 0.0 1.0 1 0 0 1 1 1 0 Centrosomal colon cancer autoantigen protein family F-box-like PF12937.7 KXH57134.1 - 0.00013 21.8 0.0 0.00036 20.4 0.0 1.8 1 0 0 1 1 1 1 F-box-like DUF3951 PF13131.6 KXH57135.1 - 0.027 14.7 1.4 0.09 13.0 1.4 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3951) DUF2975 PF11188.8 KXH57136.1 - 0.74 9.7 4.9 1.4 8.8 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2975) DUF4131 PF13567.6 KXH57136.1 - 0.83 9.3 4.8 1.1 8.9 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF1989 PF09347.10 KXH57137.1 - 1.6e-63 213.3 0.0 2e-63 213.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) Aldo_ket_red PF00248.21 KXH57227.1 - 1.4e-42 145.9 0.0 1.6e-42 145.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family UDPGT PF00201.18 KXH57228.1 - 0.0012 17.7 0.0 0.0018 17.2 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PsaM PF07465.13 KXH57228.1 - 0.022 14.5 1.1 0.055 13.2 1.1 1.6 1 0 0 1 1 1 0 Photosystem I protein M (PsaM) p450 PF00067.22 KXH57229.1 - 1.3e-53 182.4 0.0 1.6e-53 182.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ketoacyl-synt PF00109.26 KXH57230.1 - 4.3e-64 216.5 0.1 7.2e-64 215.8 0.1 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KXH57230.1 - 3.8e-54 183.3 0.1 8.4e-54 182.2 0.1 1.7 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.21 KXH57230.1 - 1.2e-44 153.2 0.1 2.2e-44 152.2 0.1 1.4 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 KXH57230.1 - 1.4e-43 149.3 0.0 2.3e-43 148.5 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 KXH57230.1 - 1.8e-34 118.3 0.0 4.6e-34 117.0 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.26 KXH57230.1 - 8.7e-16 58.1 0.0 1e-13 51.4 0.0 3.1 3 0 0 3 3 3 1 Zinc-binding dehydrogenase KAsynt_C_assoc PF16197.5 KXH57230.1 - 7.3e-14 52.2 0.0 2.6e-13 50.4 0.0 2.0 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 KXH57230.1 - 2.2e-13 50.1 2.2 8.6e-13 48.2 0.2 2.6 3 0 0 3 3 3 1 short chain dehydrogenase ADH_zinc_N_2 PF13602.6 KXH57230.1 - 1.3e-12 48.9 0.0 1.8e-11 45.2 0.0 2.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase PP-binding PF00550.25 KXH57230.1 - 1.4e-07 31.8 0.0 4.2e-07 30.2 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site TIR_2 PF13676.6 KXH57230.1 - 5e-05 23.9 0.0 0.25 11.9 0.0 2.7 2 0 0 2 2 2 2 TIR domain ADH_N PF08240.12 KXH57230.1 - 0.00025 20.9 0.0 0.00099 19.0 0.0 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Thiolase_N PF00108.23 KXH57230.1 - 0.0091 15.4 0.0 0.019 14.4 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain 3Beta_HSD PF01073.19 KXH57230.1 - 0.034 13.2 0.3 0.078 12.0 0.0 1.7 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KXH57230.1 - 0.14 11.3 0.0 0.25 10.4 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Clr5 PF14420.6 KXH57232.1 - 2.6e-13 50.0 0.1 5.6e-13 48.9 0.1 1.6 1 0 0 1 1 1 1 Clr5 domain LID PF17916.1 KXH57232.1 - 0.13 11.9 0.1 0.34 10.6 0.1 1.6 1 0 0 1 1 1 0 LIM interaction domain (LID) Furin-like PF00757.20 KXH57240.1 - 0.028 14.3 10.5 0.035 14.0 10.5 1.1 1 0 0 1 1 1 0 Furin-like cysteine rich region DUF4656 PF15551.6 KXH57240.1 - 5.1 6.5 6.6 5.5 6.4 6.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4656) ADH_N PF08240.12 KXH57370.1 - 8.6e-18 64.2 0.3 1.1e-17 63.9 0.3 1.1 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_assoc PF13823.6 KXH57370.1 - 0.0014 18.5 0.3 0.0039 17.1 0.3 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-associated PIG-S PF10510.9 KXH57465.1 - 3.6e-170 567.2 0.0 4.2e-170 567.0 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein DUF3336 PF11815.8 KXH57467.1 - 4.5e-33 113.9 0.1 1.1e-32 112.6 0.1 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3336) Patatin PF01734.22 KXH57467.1 - 1.9e-22 80.4 0.0 3.7e-22 79.5 0.0 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase CENP-H PF05837.12 KXH57467.1 - 0.64 10.4 6.2 0.41 11.1 1.8 2.2 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Sugar_tr PF00083.24 KXH57468.1 - 1.5e-102 343.8 26.2 1.9e-102 343.5 26.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH57468.1 - 6.3e-24 84.6 22.5 6.3e-24 84.6 22.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Pam17 PF08566.10 KXH57468.1 - 0.52 10.1 2.3 0.4 10.5 0.2 1.9 2 0 0 2 2 2 0 Mitochondrial import protein Pam17 DUF1769 PF08588.10 KXH57469.1 - 5.3e-27 93.8 0.5 1.2e-26 92.6 0.2 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1769) Glyco_hydro_79C PF16862.5 KXH57470.1 - 6.7e-19 68.7 1.4 1.7e-18 67.4 1.4 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 79 C-terminal beta domain Glyco_hydro_61 PF03443.14 KXH57471.1 - 9.1e-64 215.2 0.4 1.1e-63 214.9 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 NPCBM_assoc PF10633.9 KXH57471.1 - 0.011 15.9 0.1 0.92 9.8 0.0 2.6 2 1 0 2 2 2 0 NPCBM-associated, NEW3 domain of alpha-galactosidase SprB PF13573.6 KXH57471.1 - 0.42 10.4 7.4 13 5.7 0.2 3.7 3 0 0 3 3 3 0 SprB repeat SHIPPO-rpt PF07004.12 KXH57471.1 - 1.3 10.1 4.2 25 6.0 2.4 3.0 2 0 0 2 2 2 0 Sperm-tail PG-rich repeat Zn_clus PF00172.18 KXH57472.1 - 7.6e-07 29.2 7.9 1.9e-06 27.9 7.9 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Myc_N PF01056.18 KXH57473.1 - 0.0017 18.4 2.4 0.0025 17.8 2.4 1.3 1 0 0 1 1 1 1 Myc amino-terminal region Sigma70_ner PF04546.13 KXH57473.1 - 0.012 15.5 2.5 0.019 14.9 2.5 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region NOA36 PF06524.12 KXH57473.1 - 0.02 14.3 6.7 0.033 13.5 6.7 1.3 1 0 0 1 1 1 0 NOA36 protein RP-C_C PF11800.8 KXH57473.1 - 0.045 13.9 1.6 0.071 13.2 1.6 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region LAT PF15234.6 KXH57473.1 - 0.068 12.9 7.4 0.1 12.3 7.4 1.3 1 0 0 1 1 1 0 Linker for activation of T-cells BUD22 PF09073.10 KXH57473.1 - 0.12 11.6 7.7 0.17 11.2 7.7 1.1 1 0 0 1 1 1 0 BUD22 Sporozoite_P67 PF05642.11 KXH57473.1 - 0.14 10.2 2.7 0.16 10.0 2.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Radial_spoke PF04712.12 KXH57473.1 - 0.16 10.9 4.8 0.22 10.4 4.8 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein Nop14 PF04147.12 KXH57473.1 - 0.23 9.7 6.7 0.33 9.1 6.7 1.2 1 0 0 1 1 1 0 Nop14-like family Porph_ging PF09697.10 KXH57473.1 - 0.28 11.7 1.1 0.58 10.7 1.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (Porph_ging) Pox_Ag35 PF03286.14 KXH57473.1 - 0.66 9.7 8.7 0.82 9.4 6.7 2.0 3 0 0 3 3 2 0 Pox virus Ag35 surface protein PBP1_TM PF14812.6 KXH57473.1 - 1.4 9.3 5.1 2.4 8.6 5.1 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Pox_RNA_Pol_19 PF05320.12 KXH57473.1 - 1.6 8.7 8.8 3.4 7.6 8.8 1.5 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit RXT2_N PF08595.11 KXH57473.1 - 2.5 8.1 7.8 4.6 7.3 7.8 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal FAM176 PF14851.6 KXH57473.1 - 2.9 7.5 7.5 5.4 6.7 7.5 1.4 1 0 0 1 1 1 0 FAM176 family Tim54 PF11711.8 KXH57473.1 - 5.6 5.6 7.6 7.9 5.1 7.6 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Pkinase PF00069.25 KXH57474.1 - 2e-44 151.9 0.0 1.4e-43 149.2 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXH57474.1 - 2.3e-31 109.1 0.0 3.3e-31 108.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KXH57474.1 - 0.0093 15.3 0.0 0.095 12.0 0.0 2.1 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KXH57474.1 - 0.022 14.1 0.0 0.032 13.6 0.0 1.2 1 0 0 1 1 1 0 Kinase-like adh_short_C2 PF13561.6 KXH57475.1 - 7.4e-50 169.7 0.0 8.6e-50 169.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXH57475.1 - 3.6e-43 147.3 0.1 4.2e-43 147.1 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXH57475.1 - 1.8e-06 28.0 0.4 2.8e-06 27.4 0.4 1.4 1 1 0 1 1 1 1 KR domain Ldh_1_N PF00056.23 KXH57475.1 - 0.013 15.6 0.0 0.021 14.9 0.0 1.3 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain HHH_5 PF14520.6 KXH57475.1 - 0.05 14.2 0.1 0.12 13.0 0.1 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix domain Bacillus_PapR PF05968.11 KXH57475.1 - 0.26 11.2 0.5 0.57 10.1 0.5 1.6 1 0 0 1 1 1 0 Bacillus PapR protein Fungal_trans PF04082.18 KXH57476.1 - 2e-20 73.0 0.0 3.8e-20 72.0 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain CTP_transf_like PF01467.26 KXH57477.1 - 0.0002 21.6 0.0 0.00054 20.2 0.0 1.8 1 1 0 1 1 1 1 Cytidylyltransferase-like F-box-like PF12937.7 KXH57478.1 - 3.6e-05 23.6 0.2 0.00011 22.0 0.2 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXH57478.1 - 0.0002 21.1 0.1 0.00063 19.5 0.1 1.9 1 0 0 1 1 1 1 F-box domain Aldedh PF00171.22 KXH57479.1 - 6.7e-158 526.0 0.0 7.8e-158 525.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KXH57479.1 - 0.097 12.1 0.0 8.2 5.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) adh_short_C2 PF13561.6 KXH57480.1 - 1.2e-41 142.9 0.0 1.5e-41 142.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXH57480.1 - 2.7e-36 124.9 0.0 4.4e-36 124.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXH57480.1 - 2.1e-08 34.3 0.1 3.3e-08 33.7 0.1 1.3 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 KXH57480.1 - 0.12 11.7 0.0 6.2 6.1 0.0 2.1 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KXH57480.1 - 0.16 11.1 0.0 0.23 10.6 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein AMP-binding PF00501.28 KXH57481.1 - 2e-95 319.9 0.0 2.6e-95 319.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXH57481.1 - 2e-11 44.7 1.1 5.1e-11 43.4 1.1 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain WRW PF10206.9 KXH57481.1 - 0.14 12.6 0.0 0.33 11.3 0.0 1.6 1 0 0 1 1 1 0 Mitochondrial F1F0-ATP synthase, subunit f FMO-like PF00743.19 KXH57482.1 - 9.2e-15 54.1 0.0 5.1e-11 41.7 0.0 2.9 2 2 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KXH57482.1 - 5.4e-11 42.6 0.0 1.2e-10 41.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXH57482.1 - 1.2e-06 28.0 0.0 0.002 17.4 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXH57482.1 - 1.7e-06 27.5 0.0 1.7e-05 24.2 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXH57482.1 - 0.0006 19.0 0.0 0.58 9.2 0.0 3.0 3 1 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KXH57482.1 - 0.0011 18.7 0.0 2.8 7.4 0.0 3.4 2 1 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KXH57482.1 - 0.0053 16.7 0.0 0.052 13.5 0.0 2.5 3 0 0 3 3 3 1 FAD-NAD(P)-binding DUF1564 PF07600.11 KXH57483.1 - 0.021 14.5 0.0 0.029 14.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1564) DIM PF08194.12 KXH57483.1 - 0.22 11.8 1.6 3.7 7.8 0.3 2.4 2 0 0 2 2 2 0 DIM protein Apt1 PF10351.9 KXH57484.1 - 0.71 8.7 5.6 0.78 8.5 5.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 KXH57484.1 - 1.6 7.2 11.0 2 6.9 11.0 1.1 1 0 0 1 1 1 0 Macoilin family DUF572 PF04502.13 KXH57484.1 - 4.7 6.7 14.8 8.3 5.9 14.8 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF572) ExoD PF06055.12 KXH57485.1 - 0.14 11.5 0.4 0.2 11.0 0.4 1.3 1 1 0 1 1 1 0 Exopolysaccharide synthesis, ExoD LysM PF01476.20 KXH57486.1 - 1e-09 38.3 0.0 1.7e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 LysM domain Actino_peptide PF14408.6 KXH57486.1 - 0.031 14.4 0.1 0.059 13.5 0.1 1.4 1 0 0 1 1 1 0 Ribosomally synthesised peptide in actinomycetes DUF903 PF06004.12 KXH57486.1 - 0.082 12.8 1.0 0.16 11.9 1.0 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF903) Cellulase PF00150.18 KXH57487.1 - 8.2e-21 74.7 2.6 1.2e-20 74.1 2.6 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.18 KXH57487.1 - 2.1e-13 50.0 15.2 9.2e-13 47.9 15.2 2.3 1 0 0 1 1 1 1 Fungal cellulose binding domain Glyco_hydro_2_C PF02836.17 KXH57487.1 - 3.7e-05 23.0 0.1 5.6e-05 22.4 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain DUF4038 PF13204.6 KXH57487.1 - 9.8e-05 22.1 0.2 0.00015 21.6 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4038) Glyco_hydro_42 PF02449.15 KXH57487.1 - 0.00061 19.2 0.2 0.0014 18.1 0.1 1.5 2 0 0 2 2 2 1 Beta-galactosidase adh_short PF00106.25 KXH57488.1 - 6.5e-31 107.3 0.0 7.9e-31 107.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXH57488.1 - 6.8e-21 74.9 0.1 1.7e-20 73.6 0.1 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH57488.1 - 2e-08 34.3 0.0 3.2e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KXH57488.1 - 9.2e-08 31.6 0.0 1.4e-07 31.0 0.0 1.4 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KXH57488.1 - 0.023 14.1 0.0 0.083 12.3 0.0 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Glyco_tran_WecB PF03808.13 KXH57488.1 - 0.096 12.6 0.0 0.25 11.3 0.0 1.7 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family Glyco_hydro_43 PF04616.14 KXH57489.1 - 1.9e-54 184.9 1.0 3e-54 184.3 1.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 KXH57489.1 - 7.7e-26 91.1 0.0 1.2e-25 90.4 0.0 1.3 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain DUF5005 PF16396.5 KXH57489.1 - 0.023 13.4 0.1 0.34 9.6 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5005) GFA PF04828.14 KXH57490.1 - 1.2e-21 76.9 0.3 1.6e-21 76.4 0.3 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Fungal_trans_2 PF11951.8 KXH57491.1 - 6.9e-05 21.8 0.0 0.00043 19.2 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH57491.1 - 0.0016 18.5 9.3 0.0037 17.3 9.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short_C2 PF13561.6 KXH57492.1 - 6.4e-55 186.3 0.5 8.7e-55 185.8 0.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXH57492.1 - 1.4e-45 155.2 1.6 1.8e-45 154.8 1.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXH57492.1 - 1.4e-13 51.1 1.0 2e-13 50.7 1.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXH57492.1 - 0.0022 17.5 0.2 0.0058 16.1 0.2 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXH57492.1 - 0.083 12.3 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase AA_permease_2 PF13520.6 KXH57494.1 - 1.4e-41 142.7 52.2 1.7e-41 142.5 52.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXH57494.1 - 5.2e-21 74.8 41.4 8.5e-21 74.1 41.4 1.2 1 0 0 1 1 1 1 Amino acid permease PQQ_2 PF13360.6 KXH57495.1 - 0.011 15.3 0.1 0.048 13.2 0.1 2.0 1 1 0 1 1 1 0 PQQ-like domain Tachylectin PF14517.6 KXH57495.1 - 0.047 13.2 0.2 0.14 11.6 0.2 1.6 1 1 0 1 1 1 0 Tachylectin HET PF06985.11 KXH57496.1 - 6.2e-23 81.8 0.0 1.4e-22 80.6 0.0 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) WD40 PF00400.32 KXH57649.1 - 3.4e-07 30.8 13.3 0.00019 22.2 1.2 5.7 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXH57649.1 - 0.0016 18.7 0.2 0.36 11.1 0.1 3.6 2 2 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Zn_Tnp_IS1595 PF12760.7 KXH57649.1 - 0.0082 16.1 1.4 0.0082 16.1 1.4 2.5 4 0 0 4 4 4 1 Transposase zinc-ribbon domain zinc_ribbon_4 PF13717.6 KXH57649.1 - 0.18 11.8 3.9 0.073 13.0 0.7 2.1 1 1 1 2 2 2 0 zinc-ribbon domain Zn_ribbon_17 PF17120.5 KXH57649.1 - 2.2 7.9 17.6 0.071 12.7 9.7 2.3 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type Atg14 PF10186.9 KXH57650.1 - 2.5e-17 63.0 1.4 6.2e-17 61.7 1.4 1.6 1 1 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 VPS38 PF17649.1 KXH57650.1 - 1.1e-12 47.6 0.6 3.1e-07 29.6 0.0 3.5 3 1 0 3 3 3 3 Vacuolar protein sorting 38 DUF4522 PF15022.6 KXH57650.1 - 0.16 12.3 2.2 0.12 12.7 0.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4522) Snapin_Pallidin PF14712.6 KXH57650.1 - 5.8 7.4 11.9 6.3 7.3 2.0 2.8 1 1 1 2 2 2 0 Snapin/Pallidin adh_short PF00106.25 KXH57654.1 - 4.6e-27 94.7 0.0 6.9e-24 84.4 0.1 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXH57654.1 - 3.6e-15 56.2 0.0 1.4e-14 54.2 0.0 1.8 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH57654.1 - 2.1e-08 34.3 0.2 4e-08 33.4 0.2 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXH57654.1 - 0.00018 21.1 0.0 0.0004 19.9 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXH57654.1 - 0.00097 18.6 0.0 0.0015 18.0 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase ADH_zinc_N PF00107.26 KXH57654.1 - 0.012 15.6 0.1 0.056 13.4 0.0 2.1 3 0 0 3 3 3 0 Zinc-binding dehydrogenase Fungal_trans_2 PF11951.8 KXH57655.1 - 0.006 15.4 0.2 0.0081 15.0 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain FAD_binding_4 PF01565.23 KXH57656.1 - 4.7e-27 94.4 6.7 1.4e-26 92.9 6.7 1.9 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KXH57656.1 - 3e-13 49.7 0.4 5.4e-13 48.8 0.4 1.5 1 0 0 1 1 1 1 Berberine and berberine like Cupin_1 PF00190.22 KXH57657.1 - 3.4e-20 72.2 0.4 4.6e-20 71.7 0.4 1.1 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.11 KXH57657.1 - 2.6e-08 33.4 0.0 5e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.7 KXH57657.1 - 0.0064 16.2 0.0 0.0086 15.8 0.0 1.3 1 0 0 1 1 1 1 Cupin MannoseP_isomer PF01050.18 KXH57657.1 - 0.086 12.7 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase AraC_binding PF02311.19 KXH57657.1 - 0.17 11.8 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 AraC-like ligand binding domain Tyrosinase PF00264.20 KXH57658.1 - 1.1e-43 150.1 1.1 1.1e-43 150.1 1.1 1.4 2 0 0 2 2 2 1 Common central domain of tyrosinase Transferase PF02458.15 KXH57659.1 - 1.5e-23 83.1 0.0 9.9e-23 80.5 0.0 1.8 2 0 0 2 2 2 1 Transferase family CCDC106 PF15794.5 KXH57660.1 - 0.085 12.6 5.8 1.8 8.3 0.3 2.1 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 106 MFS_1 PF07690.16 KXH57661.1 - 9.2e-06 24.8 4.9 1.4e-05 24.2 4.9 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Phage_holin_3_6 PF07332.11 KXH57661.1 - 0.0086 16.1 2.0 0.022 14.8 2.0 1.7 1 0 0 1 1 1 1 Putative Actinobacterial Holin-X, holin superfamily III Beta-lactamase PF00144.24 KXH57662.1 - 2.7e-64 217.5 0.0 3.6e-64 217.1 0.0 1.0 1 0 0 1 1 1 1 Beta-lactamase adh_short PF00106.25 KXH57663.1 - 4e-20 72.1 0.0 5.9e-20 71.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXH57663.1 - 1.2e-11 44.6 0.0 1.6e-11 44.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase GDP_Man_Dehyd PF16363.5 KXH57663.1 - 3.3e-05 23.4 0.1 0.00034 20.1 0.1 2.1 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KXH57663.1 - 0.00072 19.1 0.0 0.0018 17.8 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KXH57663.1 - 0.0011 18.9 0.0 0.0014 18.5 0.0 1.1 1 0 0 1 1 1 1 KR domain Sigma54_activ_2 PF14532.6 KXH57663.1 - 0.083 13.0 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain Cellulase PF00150.18 KXH57664.1 - 2.8e-52 177.9 6.5 3.8e-52 177.5 6.5 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.18 KXH57664.1 - 7.9e-12 44.9 13.7 7.9e-12 44.9 13.7 2.6 3 0 0 3 3 3 1 Fungal cellulose binding domain FAD_binding_7 PF03441.14 KXH57665.1 - 6.1e-82 274.0 4.2 1.2e-81 273.0 0.3 2.6 3 0 0 3 3 3 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 KXH57665.1 - 2.4e-37 128.5 0.0 4.1e-37 127.7 0.0 1.3 1 0 0 1 1 1 1 DNA photolyase Cactin_mid PF10312.9 KXH57666.1 - 1.2e-65 221.0 8.2 1.6e-65 220.6 8.2 1.2 1 0 0 1 1 1 1 Conserved mid region of cactin CactinC_cactus PF09732.9 KXH57666.1 - 7.7e-58 193.9 5.3 1.3e-57 193.2 5.3 1.4 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein SF3A2 PF16835.5 KXH57666.1 - 0.0066 16.8 0.0 0.031 14.6 0.0 2.1 2 0 0 2 2 2 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) DUF1087 PF06465.13 KXH57666.1 - 0.15 12.1 2.2 0.59 10.2 0.2 2.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1087) Forkhead PF00250.18 KXH57667.1 - 8.6e-21 74.0 0.1 2.7e-20 72.4 0.1 1.8 1 0 0 1 1 1 1 Forkhead domain XLF PF09302.11 KXH57668.1 - 1.4e-57 194.7 1.0 2.1e-57 194.2 1.0 1.2 1 0 0 1 1 1 1 XLF-Cernunnos, XRcc4-like factor, NHEJ component MerR-DNA-bind PF09278.11 KXH57668.1 - 9.4 6.9 6.4 16 6.1 1.7 2.5 2 0 0 2 2 2 0 MerR, DNA binding FAD_binding_4 PF01565.23 KXH57669.1 - 5.5e-27 94.2 1.9 8.4e-27 93.6 1.9 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KXH57669.1 - 1.3e-12 47.6 0.0 2.4e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like Ribosomal_L14 PF00238.19 KXH57670.1 - 9.7e-33 112.8 0.0 1.2e-32 112.6 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e DUF5427 PF10310.9 KXH57672.1 - 1.7e-181 604.3 0.0 1.9e-181 604.1 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5427) Flu_M1_C PF08289.11 KXH57672.1 - 0.035 14.3 0.3 0.099 12.9 0.3 1.7 1 0 0 1 1 1 0 Influenza Matrix protein (M1) C-terminal domain DUF1631 PF07793.11 KXH57672.1 - 0.91 7.9 9.4 1.4 7.3 9.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) Ndc1_Nup PF09531.10 KXH57672.1 - 3.2 6.3 4.3 4.3 5.9 4.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Malic_M PF03949.15 KXH57673.1 - 6.3e-89 297.6 0.1 8.6e-89 297.2 0.1 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 KXH57673.1 - 2.1e-57 193.9 0.0 3.5e-57 193.1 0.0 1.4 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain COesterase PF00135.28 KXH57674.1 - 9.3e-92 308.5 0.0 1.1e-91 308.2 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXH57674.1 - 6.8e-07 29.4 0.1 3.4e-06 27.1 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold zf-C2H2 PF00096.26 KXH57813.1 - 4.9e-11 42.4 11.0 5.9e-05 23.3 0.7 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXH57813.1 - 7.6e-09 35.7 8.8 0.0012 19.5 0.6 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KXH57813.1 - 4e-08 33.3 11.7 2e-06 27.9 1.2 2.9 3 0 0 3 3 3 2 Zinc-finger double domain BolA PF01722.18 KXH57813.1 - 0.0017 18.6 0.1 2.7 8.3 0.0 2.3 1 1 1 2 2 2 2 BolA-like protein zf-C2H2_jaz PF12171.8 KXH57813.1 - 0.0039 17.4 3.5 0.14 12.5 0.1 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KXH57813.1 - 0.0057 16.4 8.4 0.65 9.8 0.3 2.6 2 0 0 2 2 2 2 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 KXH57813.1 - 0.027 14.4 10.9 0.21 11.6 0.2 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger C5HCH PF17982.1 KXH57813.1 - 0.12 12.6 5.3 0.91 9.7 0.6 2.6 2 0 0 2 2 2 0 NSD Cys-His rich domain zf-met PF12874.7 KXH57813.1 - 0.4 11.1 3.9 0.53 10.7 0.1 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2HE PF16278.5 KXH57813.1 - 1.2 9.6 8.5 2 8.9 1.6 2.4 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-AN1 PF01428.16 KXH57813.1 - 3.7 7.8 8.8 10 6.4 1.5 2.4 1 1 1 2 2 2 0 AN1-like Zinc finger TPR_12 PF13424.6 KXH57863.1 - 0.00023 21.4 3.8 1.2 9.4 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat DUF2533 PF10752.9 KXH57863.1 - 0.00029 21.2 0.1 0.0016 18.9 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2533) TPR_2 PF07719.17 KXH57863.1 - 0.035 14.2 4.1 9.2 6.7 0.0 4.7 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.6 KXH57863.1 - 0.44 11.5 2.4 8.1 7.6 0.0 4.3 4 1 1 5 5 5 0 Tetratricopeptide repeat SIKE PF05769.11 KXH57924.1 - 0.015 15.3 0.2 0.023 14.6 0.2 1.3 1 1 0 1 1 1 0 SIKE family F-box PF00646.33 KXH57925.1 - 0.0018 18.1 0.8 0.042 13.7 0.1 2.5 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KXH57925.1 - 0.027 14.4 0.3 0.082 12.8 0.3 1.9 1 0 0 1 1 1 0 F-box-like p450 PF00067.22 KXH58061.1 - 1.7e-30 106.2 0.0 6.7e-30 104.2 0.0 1.9 2 1 1 3 3 3 1 Cytochrome P450 F-box-like PF12937.7 KXH58062.1 - 1.3e-06 28.2 0.1 2.9e-06 27.1 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXH58062.1 - 0.00067 19.5 0.1 0.0014 18.4 0.1 1.5 1 0 0 1 1 1 1 F-box domain McrBC PF10117.9 KXH58063.1 - 0.02 14.1 0.1 0.031 13.4 0.1 1.2 1 0 0 1 1 1 0 McrBC 5-methylcytosine restriction system component LTXXQ PF07813.12 KXH58063.1 - 3.3 8.5 15.4 4 8.2 2.3 2.4 2 0 0 2 2 2 0 LTXXQ motif family protein Dna2 PF08696.11 KXH58064.1 - 1.8e-70 236.9 0.1 1.8e-70 236.9 0.1 2.1 2 1 0 2 2 2 1 DNA replication factor Dna2 AAA_12 PF13087.6 KXH58064.1 - 1.3e-51 175.1 0.0 2.8e-51 174.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KXH58064.1 - 1.7e-33 116.6 2.5 1.6e-17 64.2 0.0 3.1 2 1 1 3 3 3 2 AAA domain AAA_30 PF13604.6 KXH58064.1 - 8.2e-14 51.8 0.0 2.2e-13 50.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KXH58064.1 - 2e-12 47.7 0.1 5.6e-12 46.2 0.1 1.9 1 0 0 1 1 1 1 AAA domain Cas_Cas4 PF01930.17 KXH58064.1 - 2.6e-11 43.9 1.0 3.5e-08 33.7 0.2 2.4 2 0 0 2 2 2 2 Domain of unknown function DUF83 Viral_helicase1 PF01443.18 KXH58064.1 - 6.3e-07 29.4 0.1 0.31 10.7 0.0 3.5 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.14 KXH58064.1 - 0.00012 22.0 0.0 0.00041 20.3 0.0 2.0 1 1 0 1 1 1 1 Helicase UvrD-helicase PF00580.21 KXH58064.1 - 0.00053 19.6 0.5 0.0014 18.2 0.0 2.0 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain SRP54 PF00448.22 KXH58064.1 - 0.0013 18.4 0.1 0.0028 17.3 0.1 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain PIF1 PF05970.14 KXH58064.1 - 0.0018 17.5 0.1 0.013 14.7 0.1 2.1 1 1 0 1 1 1 1 PIF1-like helicase AAA_16 PF13191.6 KXH58064.1 - 0.0024 18.3 0.0 0.011 16.1 0.0 2.2 1 0 0 1 1 1 1 AAA ATPase domain CbiA PF01656.23 KXH58064.1 - 0.0079 16.2 0.0 0.019 15.0 0.0 1.6 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Csa1 PF06023.12 KXH58064.1 - 0.023 14.1 0.2 0.059 12.7 0.2 1.6 1 1 0 1 1 1 0 CRISPR-associated exonuclease Csa1 AAA_7 PF12775.7 KXH58064.1 - 0.03 13.8 0.0 0.069 12.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region ResIII PF04851.15 KXH58064.1 - 0.039 14.0 0.0 0.12 12.3 0.0 1.9 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DUF87 PF01935.17 KXH58064.1 - 0.04 14.0 0.2 0.12 12.4 0.2 1.8 1 0 0 1 1 1 0 Helicase HerA, central domain cobW PF02492.19 KXH58064.1 - 0.08 12.5 0.0 0.21 11.1 0.0 1.7 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.15 KXH58064.1 - 0.09 12.7 0.2 0.25 11.2 0.2 1.7 1 0 0 1 1 1 0 NTPase MobB PF03205.14 KXH58064.1 - 0.11 12.4 0.2 0.64 9.9 0.0 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.6 KXH58064.1 - 0.11 12.1 0.1 0.41 10.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 KXH58064.1 - 0.12 11.3 0.0 0.25 10.3 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 KXH58064.1 - 0.15 12.6 0.0 0.54 10.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain ESSS PF10183.9 KXH58065.1 - 3.5e-11 43.2 0.0 4.8e-11 42.8 0.0 1.3 1 1 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Aminotran_4 PF01063.19 KXH58066.1 - 3.2e-33 115.5 0.0 4e-33 115.2 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV Pkinase PF00069.25 KXH58067.1 - 1.2e-15 57.6 0.0 6.2e-15 55.3 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXH58067.1 - 1.1e-09 38.0 0.0 2.1e-08 33.8 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase DCB PF16213.5 KXH58067.1 - 0.065 12.9 0.4 0.18 11.5 0.0 1.9 2 0 0 2 2 2 0 Dimerisation and cyclophilin-binding domain of Mon2 SIR2 PF02146.17 KXH58068.1 - 5.6e-63 212.1 0.0 9.5e-63 211.3 0.0 1.4 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.13 KXH58068.1 - 1.1e-05 25.2 0.0 2.6e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.22 KXH58068.1 - 3.9e-05 23.4 0.1 0.043 13.6 0.1 2.7 3 0 0 3 3 3 2 Thiamine pyrophosphate enzyme, central domain Cation_ATPase_C PF00689.21 KXH58069.1 - 2e-42 145.0 7.8 2e-42 145.0 7.8 2.4 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KXH58069.1 - 1.2e-34 119.4 1.7 1.2e-34 119.4 1.7 2.9 3 1 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 KXH58069.1 - 5e-22 77.8 0.0 9.7e-22 76.9 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KXH58069.1 - 7.1e-20 72.2 0.6 2.7e-19 70.3 0.6 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KXH58069.1 - 4.2e-06 26.7 0.6 1.9e-05 24.5 0.4 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KXH58069.1 - 0.00012 21.7 0.0 0.0017 18.0 0.0 2.6 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus HAD PF12710.7 KXH58069.1 - 0.14 12.5 0.0 0.29 11.5 0.0 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase TTL PF03133.15 KXH58071.1 - 4.7e-55 186.8 0.0 7.2e-55 186.2 0.0 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family SurE PF01975.17 KXH58071.1 - 2.8e-52 177.4 0.0 4.4e-52 176.7 0.0 1.3 1 0 0 1 1 1 1 Survival protein SurE ATPgrasp_YheCD PF14398.6 KXH58071.1 - 7.3e-05 22.1 0.0 0.00019 20.7 0.0 1.6 1 0 0 1 1 1 1 YheC/D like ATP-grasp DASH_Duo1 PF08651.10 KXH58073.1 - 4.3e-32 109.7 1.1 6.1e-32 109.2 1.1 1.2 1 0 0 1 1 1 1 DASH complex subunit Duo1 DUF1682 PF07946.14 KXH58073.1 - 0.1 11.8 3.9 0.12 11.5 3.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DUF1035 PF06281.12 KXH58073.1 - 0.21 11.6 0.1 0.36 10.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1035) API5 PF05918.11 KXH58073.1 - 1.5 7.5 5.0 1.7 7.4 5.0 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) RNase_H2-Ydr279 PF09468.10 KXH58074.1 - 6.1e-42 143.5 0.3 6.1e-42 143.5 0.3 1.8 2 0 0 2 2 2 1 Ydr279p protein family (RNase H2 complex component) wHTH domain Ydr279_N PF17745.1 KXH58074.1 - 3.5e-24 84.9 0.0 1.1e-23 83.3 0.0 1.9 1 0 0 1 1 1 1 Ydr279p protein triple barrel domain GEN1_C PF18380.1 KXH58074.1 - 3.7 8.5 10.3 4.1 8.3 0.6 3.1 3 0 0 3 3 3 0 Holliday junction resolvase Gen1 C-terminal domain RAP1 PF07218.11 KXH58074.1 - 5.6 5.1 19.7 11 4.1 19.6 1.5 1 1 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) zf-primase PF09329.11 KXH58075.1 - 1.2e-18 66.7 1.9 2.1e-18 65.9 1.9 1.4 1 0 0 1 1 1 1 Primase zinc finger tRNA_anti-codon PF01336.25 KXH58075.1 - 0.072 13.1 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain Glyco_hydro_92 PF07971.12 KXH58077.1 - 1.8e-146 488.7 0.2 2.1e-146 488.5 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 KXH58077.1 - 2.4e-56 191.3 0.0 4.2e-56 190.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain MFS_5 PF05631.14 KXH58078.1 - 9e-70 235.3 3.7 1.3e-69 234.8 3.7 1.1 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 KXH58078.1 - 1.7e-23 83.1 28.3 1.7e-23 83.1 28.3 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH58078.1 - 6.7e-06 25.2 1.7 6.7e-06 25.2 1.7 3.1 1 1 2 3 3 3 2 Sugar (and other) transporter Tyrosinase PF00264.20 KXH58079.1 - 4.3e-27 95.8 0.0 6.5e-27 95.3 0.0 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase Tyosinase_C PF18132.1 KXH58079.1 - 8.3e-05 23.3 0.0 0.0013 19.3 0.0 2.4 1 1 0 1 1 1 1 Tyosinase C-terminal domain DHDPS PF00701.22 KXH58080.1 - 2.9e-35 121.4 0.0 3.8e-35 121.0 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Toxin_ToxA PF11584.8 KXH58080.1 - 0.14 12.2 0.0 0.36 10.8 0.0 1.7 1 0 0 1 1 1 0 Proteinaceous host-selective toxin ToxA SIR2 PF02146.17 KXH58081.1 - 2.9e-39 134.8 0.0 4.1e-39 134.3 0.0 1.2 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 KXH58081.1 - 0.034 13.9 0.0 1.4 8.6 0.0 2.4 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain DUF1936 PF09151.10 KXH58081.1 - 0.66 9.9 2.1 26 4.8 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1936) ADH_zinc_N PF00107.26 KXH58082.1 - 1.5e-22 80.0 0.0 2.6e-22 79.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXH58082.1 - 5.6e-20 71.2 6.5 9.4e-20 70.5 6.5 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KXH58082.1 - 5.1e-08 34.1 0.0 8.3e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KXH58082.1 - 0.00024 20.5 0.6 0.00045 19.6 0.4 1.5 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 KXH58082.1 - 0.0041 16.5 0.4 0.0065 15.9 0.4 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Gag_MA PF01140.19 KXH58082.1 - 0.0092 15.7 0.0 0.02 14.6 0.0 1.6 1 0 0 1 1 1 1 Matrix protein (MA), p15 Glyco_hydro_16 PF00722.21 KXH58084.1 - 1.6e-46 158.0 1.5 3.5e-46 156.9 1.5 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Macoilin PF09726.9 KXH58084.1 - 3.7 6.0 10.0 4.6 5.7 10.0 1.1 1 0 0 1 1 1 0 Macoilin family Abhydrolase_2 PF02230.16 KXH58085.1 - 7e-09 35.8 0.0 9.6e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 KXH58085.1 - 0.0012 18.4 0.0 0.0015 18.1 0.0 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 KXH58085.1 - 0.045 13.3 0.0 0.053 13.1 0.0 1.1 1 0 0 1 1 1 0 Dienelactone hydrolase family Hydrolase_4 PF12146.8 KXH58085.1 - 0.2 10.9 0.0 0.26 10.5 0.0 1.1 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Striatin PF08232.12 KXH58086.1 - 0.0097 16.5 1.1 0.015 15.9 1.1 1.3 1 0 0 1 1 1 1 Striatin family CENP-B_dimeris PF09026.10 KXH58086.1 - 0.063 13.7 8.2 1.6 9.2 3.4 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain RNA_pol_Rpc4 PF05132.14 KXH58086.1 - 4.1 7.8 5.4 15 6.0 4.9 1.9 2 0 0 2 2 2 0 RNA polymerase III RPC4 FAM176 PF14851.6 KXH58086.1 - 7.1 6.3 9.4 5 6.8 5.8 2.0 2 0 0 2 2 2 0 FAM176 family bZIP_2 PF07716.15 KXH58335.1 - 1e-05 25.5 7.1 3.1e-05 24.0 7.1 1.8 1 1 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 KXH58335.1 - 1.7e-05 24.8 3.5 2.6e-05 24.2 3.5 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 KXH58335.1 - 2.1 8.9 7.5 0.33 11.5 3.7 1.6 2 0 0 2 2 2 0 bZIP Maf transcription factor CreD PF06123.12 KXH58338.1 - 0.059 12.1 0.0 0.081 11.7 0.0 1.1 1 0 0 1 1 1 0 Inner membrane protein CreD 4HBT_3 PF13622.6 KXH58338.1 - 0.1 12.9 0.0 0.13 12.5 0.0 1.2 1 0 0 1 1 1 0 Thioesterase-like superfamily HMA PF00403.26 KXH58360.1 - 7.9e-17 61.5 0.4 1.2e-16 60.9 0.4 1.3 1 0 0 1 1 1 1 Heavy-metal-associated domain Acetyltransf_1 PF00583.25 KXH58361.1 - 0.00014 22.1 0.0 0.0019 18.4 0.0 2.6 2 1 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXH58361.1 - 0.00056 19.9 0.0 1.1 9.2 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_5 PF13444.6 KXH58361.1 - 0.0017 19.1 0.1 0.59 10.9 0.0 3.1 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXH58361.1 - 0.014 15.8 0.0 0.046 14.1 0.0 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Ribosomal_S7 PF00177.21 KXH58362.1 - 1.1e-37 129.0 1.6 1.4e-37 128.7 1.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Ribosomal_S25 PF03297.15 KXH58363.1 - 3.8e-33 113.7 3.5 5e-33 113.3 3.5 1.1 1 0 0 1 1 1 1 S25 ribosomal protein HTH_24 PF13412.6 KXH58363.1 - 0.013 15.0 0.7 0.023 14.2 0.2 1.7 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding MarR_2 PF12802.7 KXH58363.1 - 0.027 14.4 0.1 0.046 13.6 0.1 1.4 1 0 0 1 1 1 0 MarR family HTH_DeoR PF08220.12 KXH58363.1 - 0.08 12.7 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain DASH_Spc34 PF08657.10 KXH58364.1 - 0.008 16.0 1.3 0.0098 15.7 1.3 1.2 1 0 0 1 1 1 1 DASH complex subunit Spc34 FliD_N PF02465.18 KXH58364.1 - 0.024 15.3 0.4 0.032 14.9 0.4 1.3 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus HeLo PF14479.6 KXH58364.1 - 0.052 13.4 1.1 0.063 13.1 1.1 1.1 1 0 0 1 1 1 0 Prion-inhibition and propagation DASH_Spc19 PF08287.11 KXH58364.1 - 0.054 13.4 4.6 0.062 13.2 4.6 1.2 1 0 0 1 1 1 0 Spc19 DivIVA PF05103.13 KXH58364.1 - 0.068 13.3 4.9 0.088 12.9 4.9 1.1 1 0 0 1 1 1 0 DivIVA protein Ribosomal_60s PF00428.19 KXH58364.1 - 0.092 13.3 5.6 0.082 13.5 4.4 1.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein Spc7 PF08317.11 KXH58364.1 - 0.098 11.5 3.8 0.11 11.3 3.8 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein UPF0242 PF06785.11 KXH58364.1 - 0.18 11.9 2.6 0.2 11.7 2.6 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Allexi_40kDa PF05549.11 KXH58364.1 - 0.19 11.2 0.9 0.22 11.0 0.9 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein V_ATPase_I PF01496.19 KXH58364.1 - 0.2 9.5 0.8 0.22 9.4 0.8 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4512 PF14975.6 KXH58364.1 - 0.22 12.3 1.9 0.27 12.0 1.4 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4512) XhlA PF10779.9 KXH58364.1 - 1.1 9.5 4.3 1.9 8.7 4.3 1.4 1 0 0 1 1 1 0 Haemolysin XhlA CCDC53 PF10152.9 KXH58364.1 - 1.1 9.6 6.5 1.4 9.3 6.5 1.1 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex SlyX PF04102.12 KXH58364.1 - 2.3 8.9 8.1 0.11 13.2 2.2 1.8 2 0 0 2 2 2 0 SlyX Asp PF00026.23 KXH58365.1 - 2.5e-29 102.7 0.1 3.4e-29 102.3 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KXH58365.1 - 2.5e-07 31.1 0.0 0.029 14.6 0.0 3.3 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal SRAP PF02586.14 KXH58365.1 - 0.012 15.2 0.0 0.02 14.4 0.0 1.3 1 0 0 1 1 1 0 SOS response associated peptidase (SRAP) HSP70 PF00012.20 KXH58366.1 - 9.5e-58 195.8 10.7 2.8e-55 187.7 0.3 3.4 2 1 2 4 4 4 2 Hsp70 protein FAM104 PF15434.6 KXH58366.1 - 0.022 15.3 0.2 0.022 15.3 0.2 3.1 3 0 0 3 3 3 0 Family 104 MreB_Mbl PF06723.13 KXH58366.1 - 0.042 12.7 0.0 0.099 11.4 0.0 1.6 1 0 0 1 1 1 0 MreB/Mbl protein Phage_TAC_12 PF12363.8 KXH58366.1 - 0.27 11.7 4.4 3.1 8.2 0.2 3.5 3 0 0 3 3 3 0 Phage tail assembly chaperone protein, TAC DUF3484 PF11983.8 KXH58366.1 - 1.7 9.8 0.0 1.7 9.8 0.0 3.8 3 0 0 3 3 3 0 Membrane-attachment and polymerisation-promoting switch Mucin PF01456.17 KXH58366.1 - 2.3 8.2 24.2 1.8 8.5 8.5 3.3 3 0 0 3 3 3 0 Mucin-like glycoprotein Med9 PF07544.13 KXH58366.1 - 2.5 8.3 10.9 24 5.1 0.1 4.4 4 0 0 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 adh_short PF00106.25 KXH58367.1 - 1.7e-44 151.6 0.1 2.3e-44 151.2 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXH58367.1 - 8.1e-43 146.6 0.0 1.1e-42 146.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH58367.1 - 4.6e-11 43.0 0.1 8.5e-11 42.1 0.1 1.4 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 KXH58367.1 - 0.0024 17.3 0.0 0.0042 16.5 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KXH58367.1 - 0.0036 16.8 0.1 0.0082 15.6 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KXH58367.1 - 0.0092 15.9 0.0 0.017 15.0 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KXH58367.1 - 0.012 14.7 0.0 0.016 14.4 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 KXH58367.1 - 0.046 14.0 0.1 0.2 11.9 0.1 2.0 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Cation_ATPase_C PF00689.21 KXH58368.1 - 2.4e-45 154.5 9.1 2.4e-45 154.5 9.1 2.0 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KXH58368.1 - 1e-32 113.1 0.1 1e-32 113.1 0.1 2.7 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 KXH58368.1 - 2.8e-20 72.2 0.0 8e-20 70.7 0.0 1.9 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KXH58368.1 - 2.1e-18 67.4 0.5 1.3e-15 58.3 0.0 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KXH58368.1 - 7.5e-06 25.5 0.0 2.3e-05 24.0 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KXH58368.1 - 0.0017 18.2 0.4 0.0033 17.2 0.4 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase adh_short PF00106.25 KXH58369.1 - 3.4e-23 82.1 0.4 9.8e-23 80.6 0.4 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXH58369.1 - 6.2e-17 61.9 0.5 9.1e-10 38.5 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH58369.1 - 1.4e-07 31.6 0.0 2.3e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 KR domain Bromodomain PF00439.25 KXH58370.1 - 0.0002 21.4 0.0 0.00071 19.6 0.0 1.8 1 1 0 1 1 1 1 Bromodomain Mito_carr PF00153.27 KXH58371.1 - 3.6e-67 222.3 3.8 8.4e-24 83.3 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF4748 PF15932.5 KXH58371.1 - 0.11 12.3 0.6 0.36 10.6 0.6 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4748) CENP-X PF09415.10 KXH58372.1 - 6.7e-24 84.0 0.0 6.7e-24 84.0 0.0 2.0 2 0 0 2 2 2 1 CENP-S associating Centromere protein X Cu_bind_like PF02298.17 KXH58373.1 - 0.025 14.6 0.1 0.09 12.8 0.1 1.9 1 1 0 1 1 1 0 Plastocyanin-like domain Cupredoxin_1 PF13473.6 KXH58373.1 - 0.046 13.8 0.1 0.2 11.8 0.1 1.9 1 1 1 2 2 2 0 Cupredoxin-like domain DUF2263 PF10021.9 KXH58373.1 - 0.13 12.7 0.3 0.2 12.0 0.3 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2263) Cyt-b5 PF00173.28 KXH58374.1 - 1.2e-09 38.1 0.0 1.9e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Macoilin PF09726.9 KXH58375.1 - 0.039 12.5 15.2 0.059 11.9 15.2 1.1 1 0 0 1 1 1 0 Macoilin family DUF4875 PF16175.5 KXH58375.1 - 0.082 13.0 1.3 3.5 7.8 0.7 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4875) BTB_2 PF02214.22 KXH58376.1 - 5.3e-07 29.9 0.1 0.001 19.3 0.0 2.4 2 0 0 2 2 2 2 BTB/POZ domain AMP-binding PF00501.28 KXH58506.1 - 8.2e-44 149.9 0.0 1.1e-43 149.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 KXH58506.1 - 6.7e-11 41.9 1.3 1.6e-10 40.7 0.1 2.1 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 KXH58506.1 - 3.6e-05 24.6 0.6 0.00011 23.1 0.2 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ELFV_dehydrog PF00208.21 KXH58507.1 - 5e-65 219.6 0.0 7.8e-65 219.0 0.0 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 KXH58507.1 - 2.9e-17 61.6 0.0 1.4e-12 46.1 0.0 2.5 2 1 0 3 3 3 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.18 KXH58507.1 - 0.0037 17.1 0.0 0.021 14.7 0.0 2.1 2 0 0 2 2 2 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Aminotran_5 PF00266.19 KXH58509.1 - 5.8e-08 32.1 0.0 1.4e-05 24.2 0.0 2.6 2 1 0 2 2 2 2 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 KXH58509.1 - 0.00012 20.7 0.0 0.00018 20.2 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 KXH58509.1 - 0.0059 16.0 0.1 0.012 15.0 0.1 1.4 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cwf_Cwc_15 PF04889.12 KXH58511.1 - 0.055 13.2 8.0 0.089 12.5 8.0 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SAM_2 PF07647.17 KXH58512.1 - 1.4e-16 60.3 0.0 2.7e-16 59.4 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KXH58512.1 - 1.5e-15 57.4 0.0 2.6e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.23 KXH58512.1 - 8.1e-11 42.4 0.0 1.9e-10 41.3 0.0 1.6 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SAM_4 PF18017.1 KXH58512.1 - 0.00038 20.4 0.0 0.00067 19.6 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) CCDC66 PF15236.6 KXH58512.1 - 0.77 9.6 3.1 2.2 8.1 0.1 2.4 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 66 adh_short PF00106.25 KXH58616.1 - 2.6e-52 177.1 0.0 4.2e-52 176.4 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXH58616.1 - 5.4e-37 127.6 0.0 9.9e-37 126.7 0.0 1.4 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH58616.1 - 9.8e-10 38.6 1.3 6.4e-09 36.0 0.1 2.0 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KXH58616.1 - 0.00024 20.6 0.9 0.00081 18.9 0.1 2.1 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 KXH58616.1 - 0.028 13.8 0.0 0.042 13.2 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) adh_short PF00106.25 KXH58617.1 - 1.6e-25 89.7 0.0 7.8e-25 87.5 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXH58617.1 - 1.5e-15 57.4 0.0 5.5e-15 55.6 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH58617.1 - 4e-07 30.1 1.3 1.2e-06 28.6 1.3 1.8 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KXH58617.1 - 0.00046 19.7 0.1 0.0015 18.0 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXH58617.1 - 0.00094 18.7 0.0 0.028 13.8 0.0 2.0 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase MFS_1 PF07690.16 KXH58618.1 - 1.8e-38 132.4 37.4 4.5e-37 127.8 21.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily p450 PF00067.22 KXH58619.1 - 4.5e-46 157.6 0.0 6e-46 157.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF4199 PF13858.6 KXH58620.1 - 0.071 13.5 1.5 0.1 13.0 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) Dehydrin PF00257.19 KXH58621.1 - 5.4 7.5 16.2 5.7 7.5 16.2 1.1 1 0 0 1 1 1 0 Dehydrin OPT PF03169.15 KXH58623.1 - 2.3e-188 627.7 53.7 2.6e-188 627.5 53.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF2937 PF11157.8 KXH58623.1 - 0.03 14.0 0.1 8.5 6.1 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) EIAV_GP90 PF00971.18 KXH58623.1 - 0.56 8.8 4.9 0.38 9.4 0.1 2.2 2 0 0 2 2 2 0 EIAV coat protein, gp90 Pyridoxal_deC PF00282.19 KXH58624.1 - 8.5e-67 225.5 0.0 1.2e-66 224.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 KXH58624.1 - 0.00089 18.3 0.0 0.0015 17.6 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Rpr2 PF04032.16 KXH58625.1 - 2.8e-24 85.2 1.6 3.7e-24 84.8 1.6 1.2 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain HNH_5 PF14279.6 KXH58625.1 - 0.14 12.1 2.5 0.74 9.7 2.7 2.1 1 1 1 2 2 2 0 HNH endonuclease DEAD PF00270.29 KXH58626.1 - 3.3e-39 134.5 0.1 5.5e-39 133.7 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXH58626.1 - 1.1e-24 86.9 0.3 2.7e-23 82.4 0.1 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXH58626.1 - 5.5e-08 33.0 0.0 1.3e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 KXH58626.1 - 0.033 13.5 0.2 0.15 11.4 0.1 1.9 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit DUF4844 PF16133.5 KXH58626.1 - 0.095 13.3 0.6 0.22 12.1 0.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4844) Cyclin PF08613.11 KXH58627.1 - 6e-07 30.0 0.8 1.3e-06 28.8 0.0 2.0 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 KXH58627.1 - 0.081 12.7 0.0 0.18 11.6 0.0 1.6 1 1 0 1 1 1 0 Cyclin, N-terminal domain ATP12 PF07542.11 KXH58647.1 - 2.1e-41 141.0 0.1 5.3e-41 139.7 0.1 1.7 1 0 0 1 1 1 1 ATP12 chaperone protein Asp PF00026.23 KXH58649.1 - 5.7e-49 167.2 0.0 7.8e-49 166.8 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KXH58649.1 - 1.6e-11 44.8 0.3 1.6e-11 44.8 0.3 2.8 3 1 0 3 3 3 1 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.6 KXH58649.1 - 0.0064 17.0 0.3 2.2 8.9 0.1 3.4 2 1 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KXH58649.1 - 0.013 16.1 0.1 3.7 8.2 0.0 3.2 2 0 0 2 2 2 0 Aspartyl protease Period_C PF12114.8 KXH58649.1 - 10 5.7 6.5 19 4.8 6.5 1.4 1 0 0 1 1 1 0 Period protein 2/3C-terminal region 2OG-FeII_Oxy_2 PF13532.6 KXH58650.1 - 1.3e-20 74.4 0.0 2.8e-20 73.3 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Toxin_2 PF00451.19 KXH58650.1 - 0.14 12.5 2.4 0.46 10.8 2.4 1.9 1 0 0 1 1 1 0 Scorpion short toxin, BmKK2 AMP-binding PF00501.28 KXH58651.1 - 7.5e-73 245.5 0.0 9.5e-73 245.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXH58651.1 - 6e-14 52.8 1.4 3.5e-13 50.3 1.8 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain AAA PF00004.29 KXH58778.1 - 7.7e-44 149.3 0.0 1.3e-43 148.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KXH58778.1 - 2.3e-14 52.9 0.0 4.3e-14 52.0 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 KXH58778.1 - 1.1e-07 31.9 0.0 2.7e-07 30.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KXH58778.1 - 1.4e-07 31.8 0.0 2.6e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KXH58778.1 - 4.4e-06 27.2 0.0 0.00011 22.6 0.0 2.6 2 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 KXH58778.1 - 2.5e-05 24.5 0.2 0.006 16.9 0.2 2.4 1 1 0 1 1 1 1 AAA domain Prot_ATP_ID_OB PF16450.5 KXH58778.1 - 3.3e-05 23.8 2.7 8.8e-05 22.4 2.7 1.8 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain RuvB_N PF05496.12 KXH58778.1 - 5.8e-05 22.9 0.0 0.00011 22.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 KXH58778.1 - 0.00059 20.4 0.0 0.019 15.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 KXH58778.1 - 0.001 18.4 0.0 0.002 17.4 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 KXH58778.1 - 0.0015 18.7 0.0 0.0029 17.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KXH58778.1 - 0.0029 17.4 0.0 0.0052 16.5 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_3 PF07726.11 KXH58778.1 - 0.0032 17.3 0.0 0.01 15.7 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 KXH58778.1 - 0.0061 15.9 0.1 0.019 14.3 0.0 1.8 2 0 0 2 2 2 1 KaiC Prot_ATP_OB_N PF17758.1 KXH58778.1 - 0.0073 15.9 0.1 0.024 14.3 0.1 1.9 1 0 0 1 1 1 1 Proteasomal ATPase OB N-terminal domain Mg_chelatase PF01078.21 KXH58778.1 - 0.008 15.6 0.0 0.017 14.5 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TsaE PF02367.17 KXH58778.1 - 0.011 15.8 0.0 0.02 14.9 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 KXH58778.1 - 0.011 15.9 0.0 0.02 15.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 KXH58778.1 - 0.021 14.0 0.0 0.038 13.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Sigma54_activat PF00158.26 KXH58778.1 - 0.023 14.4 0.0 0.097 12.4 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_7 PF12775.7 KXH58778.1 - 0.027 14.0 0.0 0.044 13.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region PhoH PF02562.16 KXH58778.1 - 0.029 13.8 0.0 0.14 11.6 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein AAA_24 PF13479.6 KXH58778.1 - 0.032 14.0 0.0 0.1 12.3 0.0 1.8 3 0 0 3 3 2 0 AAA domain RNA_helicase PF00910.22 KXH58778.1 - 0.034 14.5 0.0 0.064 13.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.6 KXH58778.1 - 0.034 14.2 0.0 0.059 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain HR1 PF02185.16 KXH58778.1 - 0.052 13.7 1.0 0.13 12.4 1.0 1.6 1 0 0 1 1 1 0 Hr1 repeat AAA_25 PF13481.6 KXH58778.1 - 0.057 13.0 0.0 0.17 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 KXH58778.1 - 0.057 12.5 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF2072 PF09845.9 KXH58778.1 - 0.062 13.6 0.1 0.12 12.6 0.1 1.5 1 0 0 1 1 1 0 Zn-ribbon containing protein Zeta_toxin PF06414.12 KXH58778.1 - 0.11 11.8 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Y_phosphatase PF00102.27 KXH58779.1 - 2.5e-59 200.7 0.0 1e-32 113.6 0.0 3.2 3 0 0 3 3 3 3 Protein-tyrosine phosphatase Rhodanese PF00581.20 KXH58779.1 - 3.7e-12 46.7 0.0 1e-11 45.3 0.0 1.8 1 0 0 1 1 1 1 Rhodanese-like domain DSPc PF00782.20 KXH58779.1 - 0.025 14.4 0.1 0.056 13.3 0.1 1.5 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KXH58779.1 - 0.057 13.4 0.2 0.12 12.4 0.2 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family Tcp11 PF05794.13 KXH58780.1 - 1.5e-99 334.1 0.3 1.5e-99 334.1 0.3 2.5 3 0 0 3 3 3 1 T-complex protein 11 NTS PF15447.6 KXH58780.1 - 0.12 12.9 1.0 13 6.3 0.0 3.4 4 0 0 4 4 4 0 N-terminal segments of PfEMP1 ERAP1_C PF11838.8 KXH58782.1 - 1.3e-87 294.3 0.0 6.1e-87 292.1 0.0 1.9 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 KXH58782.1 - 1.6e-79 266.5 4.0 2.3e-79 266.0 4.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 KXH58782.1 - 8.3e-49 166.3 0.9 1.5e-48 165.5 0.4 1.7 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain DUF45 PF01863.17 KXH58782.1 - 0.046 13.7 0.1 0.29 11.1 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function DUF45 JmjC PF02373.22 KXH58783.1 - 8.7e-37 126.0 0.5 2e-36 124.9 0.5 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase zf-HC5HC2H_2 PF13832.6 KXH58783.1 - 2.4e-21 75.9 5.4 4.3e-21 75.1 5.4 1.4 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 KXH58783.1 - 8.9e-21 73.9 5.4 8.9e-21 73.9 5.4 2.3 2 0 0 2 2 2 1 PHD-like zinc-binding domain JmjN PF02375.17 KXH58783.1 - 1.2e-13 50.8 0.3 2.8e-13 49.6 0.3 1.7 1 0 0 1 1 1 1 jmjN domain Cwf_Cwc_15 PF04889.12 KXH58783.1 - 4.6 6.9 15.9 3.6 7.2 2.8 2.8 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein PAP2 PF01569.21 KXH58784.1 - 3.1e-20 72.3 0.9 1.1e-19 70.5 0.9 1.9 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 KXH58784.1 - 0.00029 20.6 2.3 0.00029 20.6 2.3 2.4 3 0 0 3 3 3 1 PAP2 superfamily Peptidase_U4 PF03419.13 KXH58784.1 - 0.12 11.6 1.7 0.15 11.3 0.1 1.9 2 0 0 2 2 2 0 Sporulation factor SpoIIGA adh_short PF00106.25 KXH58785.1 - 8.9e-24 84.0 0.8 1.3e-13 50.9 0.1 2.0 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXH58785.1 - 4e-17 62.5 2.0 1.1e-11 44.8 0.1 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH58785.1 - 1.5e-10 41.3 0.0 2.1e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXH58785.1 - 1.4e-05 24.7 0.3 6.2e-05 22.6 0.3 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 KXH58785.1 - 0.0005 20.3 0.1 0.0016 18.7 0.1 1.8 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Polysacc_synt_2 PF02719.15 KXH58785.1 - 0.0011 18.2 0.0 0.039 13.1 0.0 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3HCDH_N PF02737.18 KXH58785.1 - 0.0019 18.1 0.0 0.0024 17.8 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 KXH58785.1 - 0.022 15.3 0.0 0.052 14.1 0.0 1.6 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent GDP_Man_Dehyd PF16363.5 KXH58785.1 - 0.04 13.3 0.7 2 7.7 0.7 2.0 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase ApbA PF02558.16 KXH58785.1 - 0.062 12.9 0.0 0.071 12.8 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DFP PF04127.15 KXH58785.1 - 0.07 13.0 1.4 4.9 6.9 0.1 2.1 1 1 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein RmlD_sub_bind PF04321.17 KXH58785.1 - 0.085 11.9 0.0 0.14 11.3 0.0 1.5 1 1 0 1 1 1 0 RmlD substrate binding domain MFS_1 PF07690.16 KXH58793.1 - 2.1e-09 36.8 10.6 7e-09 35.1 8.5 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Tir_receptor_C PF07489.11 KXH58986.1 - 1 9.3 7.4 1.3 8.9 7.4 1.1 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus DUF3439 PF11921.8 KXH58986.1 - 3.4 7.7 12.9 6.1 6.8 12.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Adap_comp_sub PF00928.21 KXH58987.1 - 1.1e-90 303.6 0.0 1.9e-90 302.8 0.0 1.4 2 0 0 2 2 2 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KXH58987.1 - 6.9e-09 35.8 0.2 1.1e-08 35.1 0.2 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain SET PF00856.28 KXH58989.1 - 3.1e-20 73.2 0.0 6.2e-20 72.3 0.0 1.5 1 0 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.11 KXH58989.1 - 4e-12 46.9 0.9 9.7e-12 45.7 0.9 1.7 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding Methyltransf_31 PF13847.6 KXH58990.1 - 0.33 10.7 1.5 1.9 8.3 0.3 2.0 2 0 0 2 2 2 0 Methyltransferase domain DUF3176 PF11374.8 KXH58991.1 - 1.7e-34 118.3 5.4 2.7e-34 117.6 1.5 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) HET PF06985.11 KXH58992.1 - 6.2e-19 68.8 0.2 1.4e-18 67.6 0.2 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DIOX_N PF14226.6 KXH58993.1 - 2.5e-26 92.8 0.1 4e-26 92.1 0.1 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KXH58993.1 - 3.3e-24 85.3 0.0 1e-23 83.8 0.0 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Transp_cyt_pur PF02133.15 KXH58994.1 - 1.9e-100 336.7 45.2 2.2e-100 336.5 45.2 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF3716 PF12511.8 KXH58995.1 - 1e-05 25.5 2.3 2e-05 24.6 2.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) Cupin_3 PF05899.12 KXH58995.1 - 0.13 12.0 0.0 0.49 10.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF861) GP67 PF17634.2 KXH58995.1 - 4.4 7.8 12.3 9.6 6.7 12.3 1.5 1 0 0 1 1 1 0 Gene product 67 Ribosomal_L27 PF01016.19 KXH58996.1 - 1.1e-25 89.5 0.3 2.7e-25 88.2 0.0 1.8 2 0 0 2 2 2 1 Ribosomal L27 protein DUF2076 PF09849.9 KXH58997.1 - 0.0013 18.8 0.4 0.0013 18.8 0.4 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) IPP-2 PF04979.14 KXH58998.1 - 1.2e-24 87.5 12.2 1.2e-24 87.5 12.2 2.0 2 0 0 2 2 2 1 Protein phosphatase inhibitor 2 (IPP-2) AAA_16 PF13191.6 KXH58999.1 - 8.9e-08 32.7 0.2 3.9e-07 30.6 0.2 2.1 1 1 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 KXH58999.1 - 0.00033 20.6 0.0 0.00066 19.7 0.0 1.5 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea DUF815 PF05673.13 KXH58999.1 - 0.00094 18.4 0.0 0.0024 17.1 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_25 PF13481.6 KXH58999.1 - 0.019 14.5 0.0 0.059 12.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KXH58999.1 - 0.026 14.3 0.1 0.069 12.9 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATPase PF06745.13 KXH58999.1 - 0.036 13.4 0.3 0.12 11.7 0.0 1.9 2 0 0 2 2 2 0 KaiC HisKA PF00512.25 KXH58999.1 - 0.064 13.3 0.0 0.2 11.7 0.0 1.7 1 0 0 1 1 1 0 His Kinase A (phospho-acceptor) domain AAA_22 PF13401.6 KXH58999.1 - 0.068 13.4 0.4 0.28 11.5 0.4 2.0 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KXH58999.1 - 0.093 12.2 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region NTPase_1 PF03266.15 KXH58999.1 - 0.14 12.1 0.0 0.33 10.8 0.0 1.6 1 0 0 1 1 1 0 NTPase Dioxygenase_C PF00775.21 KXH59000.1 - 2.6e-07 30.3 0.0 4.4e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Dioxygenase Zn_clus PF00172.18 KXH59001.1 - 6.1e-05 23.1 8.5 6.1e-05 23.1 8.5 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXH59001.1 - 0.00054 19.1 0.1 0.0023 17.0 0.1 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Oxidored_q6 PF01058.22 KXH59002.1 - 1.8e-22 79.6 0.0 2e-22 79.4 0.0 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit DEC-1_C PF04626.13 KXH59002.1 - 0.056 13.8 0.3 0.076 13.4 0.3 1.2 1 0 0 1 1 1 0 Dec-1 protein, C terminal region PAF-AH_p_II PF03403.13 KXH59003.1 - 0.00052 18.6 0.0 0.29 9.6 0.0 2.6 2 1 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II MTES_1575 PF18741.1 KXH59003.1 - 0.21 11.8 0.9 0.91 9.7 0.9 1.9 1 1 0 1 1 1 0 REase_MTES_1575 Glyco_hydro_43 PF04616.14 KXH59004.1 - 8e-59 199.3 0.8 1e-58 198.9 0.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 KXH59004.1 - 7.4e-09 35.6 0.0 1.2e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain Neur_chan_memb PF02932.16 KXH59005.1 - 0.035 14.2 2.1 0.052 13.6 2.1 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CSG2 PF16965.5 KXH59005.1 - 1.7 7.5 3.7 4.2 6.2 3.7 1.7 1 1 0 1 1 1 0 Ceramide synthase regulator DUF3679 PF12438.8 KXH59005.1 - 6.7 6.5 7.3 0.36 10.6 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3679) FAM167 PF11652.8 KXH59006.1 - 0.56 10.7 3.8 5.1 7.6 0.1 2.5 1 1 1 2 2 2 0 FAM167 DEAD PF00270.29 KXH59007.1 - 1.1e-20 74.1 0.3 8e-20 71.3 0.0 2.5 4 0 0 4 4 4 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXH59007.1 - 2.8e-18 66.3 0.0 2.2e-16 60.2 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 KXH59007.1 - 5.4e-05 23.8 2.7 8.9e-05 23.1 0.3 2.4 2 0 0 2 2 2 1 RecQ zinc-binding MFS_1 PF07690.16 KXH59008.1 - 4.7e-25 88.2 31.9 1.3e-24 86.8 24.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH59008.1 - 1e-11 44.4 20.6 3.1e-07 29.6 10.6 3.1 2 1 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.13 KXH59008.1 - 4.7e-08 31.9 3.4 7.5e-08 31.2 3.4 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Pro_racemase PF05544.11 KXH59009.1 - 4.8e-126 420.2 0.0 5.5e-126 420.0 0.0 1.0 1 0 0 1 1 1 1 Proline racemase Fungal_trans_2 PF11951.8 KXH59010.1 - 1.3e-21 76.9 0.1 1.7e-21 76.5 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH59010.1 - 0.00045 20.3 8.5 0.0011 19.0 8.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1035 PF06281.12 KXH59011.1 - 0.33 11.0 2.2 4.3 7.4 0.3 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1035) Glyco_hydro_61 PF03443.14 KXH59012.1 - 2.7e-64 216.9 0.1 2.7e-64 216.9 0.1 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 CBM_1 PF00734.18 KXH59012.1 - 7e-23 80.3 19.6 1.5e-11 44.1 6.0 2.7 2 0 0 2 2 2 2 Fungal cellulose binding domain CSD PF00313.22 KXH59012.1 - 0.088 12.7 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 'Cold-shock' DNA-binding domain Velvet PF11754.8 KXH59012.1 - 0.16 11.9 8.6 0.29 11.0 8.6 1.4 1 0 0 1 1 1 0 Velvet factor KAR9 PF08580.10 KXH59012.1 - 0.39 9.2 12.5 0.49 8.9 12.5 1.0 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Mito_carr PF00153.27 KXH59013.1 - 2.3e-15 56.3 6.5 3.3e-05 23.7 0.1 4.9 3 2 0 3 3 3 3 Mitochondrial carrier protein DUF908 PF06012.12 KXH59013.1 - 0.15 11.5 0.3 0.23 10.8 0.3 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Fer2 PF00111.27 KXH59014.1 - 3.5e-14 52.5 1.0 5e-14 52.0 1.0 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Herpes_UL49_2 PF04823.12 KXH59014.1 - 0.085 13.0 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 Herpesvirus UL49 tegument protein Rrp15p PF07890.12 KXH59015.1 - 3.6e-40 137.4 14.1 3.6e-40 137.4 14.1 2.3 2 1 0 2 2 2 1 Rrp15p Paramyxo_NS_C PF02725.14 KXH59015.1 - 0.64 10.1 3.2 0.3 11.2 0.4 1.8 2 0 0 2 2 2 0 Non-structural protein C Prenyltransf PF01255.19 KXH59133.1 - 0.08 12.4 0.0 0.92 9.0 0.0 2.0 2 0 0 2 2 2 0 Putative undecaprenyl diphosphate synthase 2OG-FeII_Oxy_2 PF13532.6 KXH59134.1 - 2.9e-27 96.1 0.0 3.7e-27 95.8 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Met_10 PF02475.16 KXH59135.1 - 1.8e-72 243.3 0.1 2.8e-72 242.6 0.1 1.3 1 0 0 1 1 1 1 Met-10+ like-protein TRM PF02005.16 KXH59135.1 - 0.048 12.8 0.0 0.077 12.2 0.0 1.2 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase MFS_1 PF07690.16 KXH59139.1 - 1e-31 110.2 25.5 1e-31 110.2 25.5 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1129 PF06570.11 KXH59139.1 - 0.08 12.4 1.2 0.4 10.1 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1129) DUF3830 PF12903.7 KXH59140.1 - 1.9e-27 95.8 0.0 2.2e-27 95.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3830) TauD PF02668.16 KXH59141.1 - 1.8e-45 155.8 0.8 2.4e-45 155.4 0.8 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Fungal_trans PF04082.18 KXH59142.1 - 2.9e-08 33.1 0.4 5.9e-07 28.8 0.2 2.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain Cupin_1 PF00190.22 KXH59143.1 - 1e-06 28.4 0.0 1.4e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.11 KXH59143.1 - 9.9e-06 25.2 0.7 3.9e-05 23.3 0.7 1.9 1 1 0 1 1 1 1 Cupin domain Auxin_BP PF02041.16 KXH59143.1 - 0.061 13.0 0.0 0.083 12.6 0.0 1.2 1 0 0 1 1 1 0 Auxin binding protein RecT PF03837.14 KXH59143.1 - 0.16 11.5 0.0 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 RecT family AA_permease PF00324.21 KXH59144.1 - 2.5e-58 197.8 28.2 5.8e-40 137.3 12.8 2.0 1 1 0 2 2 2 2 Amino acid permease AA_permease_2 PF13520.6 KXH59144.1 - 3.1e-15 56.0 29.7 3.4e-11 42.6 13.2 2.0 1 1 1 2 2 2 2 Amino acid permease FMO-like PF00743.19 KXH59145.1 - 6.5e-11 41.4 0.0 4.1e-10 38.7 0.0 1.9 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KXH59145.1 - 1.5e-10 40.8 0.0 8.7e-09 35.0 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXH59145.1 - 2.6e-09 37.2 0.3 1.6e-08 34.7 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KXH59145.1 - 1.2e-07 31.3 0.0 1.1e-06 28.1 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXH59145.1 - 1.5e-05 25.1 1.0 0.0017 18.3 0.0 3.2 3 0 0 3 3 3 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 KXH59145.1 - 1.8e-05 24.1 0.0 0.0016 17.6 0.0 2.8 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.12 KXH59145.1 - 3.5e-05 23.0 0.0 0.00062 18.9 0.0 2.6 2 1 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.24 KXH59145.1 - 8e-05 22.4 0.0 0.002 17.8 0.0 2.7 3 0 0 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.17 KXH59145.1 - 0.0035 16.6 0.0 0.0083 15.4 0.0 1.5 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 KXH59145.1 - 0.0039 17.7 0.5 0.38 11.3 0.2 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 KXH59145.1 - 0.0053 16.1 0.0 0.012 15.0 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KXH59145.1 - 0.0056 16.8 0.0 2.2 8.4 0.0 2.5 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.24 KXH59145.1 - 0.027 13.6 0.0 0.041 13.0 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 KXH59145.1 - 0.032 12.9 0.0 0.069 11.8 0.0 1.5 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.22 KXH59145.1 - 0.08 12.0 0.1 3.9 6.4 0.1 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_4 PF07993.12 KXH59146.1 - 0.0006 19.1 0.0 0.0069 15.6 0.0 2.0 2 0 0 2 2 2 1 Male sterility protein Epimerase PF01370.21 KXH59146.1 - 0.019 14.4 0.0 0.038 13.5 0.0 1.5 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KXH59146.1 - 0.022 13.8 0.1 0.039 13.0 0.0 1.4 2 0 0 2 2 2 0 RmlD substrate binding domain NAD_binding_10 PF13460.6 KXH59146.1 - 0.074 12.9 0.0 0.16 11.8 0.0 1.5 1 1 0 1 1 1 0 NAD(P)H-binding 3Beta_HSD PF01073.19 KXH59146.1 - 0.11 11.5 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.20 KXH59146.1 - 0.15 12.2 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.24 KXH59146.1 - 0.17 12.3 0.0 0.32 11.5 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain CoA_transf_3 PF02515.17 KXH59147.1 - 8.7e-40 137.0 0.1 3.2e-39 135.1 0.1 1.8 2 0 0 2 2 2 1 CoA-transferase family III 3HCDH_N PF02737.18 KXH59148.1 - 1.1e-48 165.5 0.0 1.5e-48 165.0 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 KXH59148.1 - 2.9e-15 56.6 0.0 6.1e-15 55.6 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain UDPG_MGDP_dh_N PF03721.14 KXH59148.1 - 0.00087 18.9 0.0 0.0014 18.2 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.19 KXH59148.1 - 0.0014 18.0 0.0 0.0026 17.1 0.0 1.5 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 KXH59148.1 - 0.015 15.3 0.0 0.066 13.2 0.0 2.0 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.16 KXH59148.1 - 0.022 14.4 0.1 0.043 13.5 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA AlaDh_PNT_C PF01262.21 KXH59148.1 - 0.031 13.6 0.0 0.069 12.4 0.0 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_2 PF03446.15 KXH59148.1 - 0.096 12.8 0.0 0.096 12.8 0.0 2.4 3 0 0 3 3 3 0 NAD binding domain of 6-phosphogluconate dehydrogenase Ldl_recept_b PF00058.17 KXH59149.1 - 3.9e-11 43.3 5.0 0.0025 18.2 0.1 5.4 5 1 0 5 5 5 3 Low-density lipoprotein receptor repeat class B SGL PF08450.12 KXH59149.1 - 3.3e-05 23.6 0.4 2.6 7.6 0.0 3.1 2 1 0 3 3 3 3 SMP-30/Gluconolactonase/LRE-like region DUF5074 PF16819.5 KXH59149.1 - 0.0029 17.6 0.0 0.053 13.6 0.0 2.7 2 1 2 4 4 4 1 Domain of unknown function (DUF5074) Str_synth PF03088.16 KXH59149.1 - 0.024 14.7 0.0 20 5.4 0.0 3.5 3 0 0 3 3 3 0 Strictosidine synthase EHN PF06441.12 KXH59150.1 - 2.6e-28 98.5 0.1 4.6e-28 97.7 0.1 1.4 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 KXH59150.1 - 5.4e-07 29.5 0.0 2.1e-06 27.6 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXH59150.1 - 0.012 16.2 0.2 0.028 15.0 0.2 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family NmrA PF05368.13 KXH59151.1 - 1.2e-13 51.2 0.0 1.6e-13 50.8 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXH59151.1 - 4.1e-12 46.4 0.1 1.7e-11 44.3 0.1 1.9 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KXH59151.1 - 4.7e-10 39.3 0.8 4e-05 23.2 0.4 2.3 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family KR PF08659.10 KXH59151.1 - 0.014 15.4 0.1 0.021 14.7 0.1 1.4 1 0 0 1 1 1 0 KR domain Semialdhyde_dh PF01118.24 KXH59151.1 - 0.021 15.3 0.1 0.09 13.2 0.1 2.0 2 1 1 3 3 3 0 Semialdehyde dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 KXH59151.1 - 0.031 13.7 0.3 0.53 9.6 0.0 2.1 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase TrkA_N PF02254.18 KXH59151.1 - 0.032 14.5 0.1 0.051 13.8 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain RmlD_sub_bind PF04321.17 KXH59151.1 - 0.15 11.1 0.7 2.3 7.2 0.2 2.1 2 0 0 2 2 2 0 RmlD substrate binding domain Alpha-L-AF_C PF06964.12 KXH59152.1 - 3e-27 95.8 0.0 4.5e-27 95.2 0.0 1.2 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain Aldo_ket_red PF00248.21 KXH59153.1 - 3.9e-58 197.0 0.0 4.4e-58 196.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Rx_N PF18052.1 KXH59154.1 - 0.024 14.9 0.1 0.22 11.8 0.0 2.4 2 0 0 2 2 2 0 Rx N-terminal domain Cu_amine_oxid PF01179.20 KXH59155.1 - 2.8e-152 507.4 0.0 3.4e-152 507.1 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.16 KXH59155.1 - 5e-07 29.9 0.0 8.9e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.16 KXH59155.1 - 1.8e-05 25.0 0.0 4.2e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain adh_short_C2 PF13561.6 KXH59156.1 - 1.7e-50 171.8 2.2 1.9e-50 171.6 2.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXH59156.1 - 5.8e-46 156.4 3.8 7.6e-46 156.0 3.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXH59156.1 - 9.6e-20 71.2 1.1 1.3e-19 70.9 1.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXH59156.1 - 2.7e-05 23.8 1.4 0.00018 21.1 1.4 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXH59156.1 - 0.0054 16.2 0.2 0.46 9.8 0.1 2.1 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase THF_DHG_CYH_C PF02882.19 KXH59156.1 - 0.013 14.8 0.0 0.021 14.1 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Fungal_trans_2 PF11951.8 KXH59157.1 - 1.6e-12 46.9 0.5 1.8e-12 46.8 0.5 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain PhyH PF05721.13 KXH59158.1 - 8.6e-22 78.4 0.2 1.3e-21 77.9 0.2 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Fungal_trans_2 PF11951.8 KXH59158.1 - 4.1e-10 39.0 0.2 7.8e-10 38.1 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH59158.1 - 1.1e-06 28.6 14.4 2.4e-06 27.5 14.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Brix PF04427.18 KXH59159.1 - 8.3e-45 153.3 0.0 1.1e-44 152.8 0.0 1.2 1 0 0 1 1 1 1 Brix domain DUF4647 PF15504.6 KXH59159.1 - 0.02 14.0 4.9 0.029 13.5 4.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) DEAD PF00270.29 KXH59160.1 - 3.1e-46 157.3 0.0 4.9e-46 156.7 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXH59160.1 - 9.5e-31 106.4 0.2 8.9e-30 103.3 0.1 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXH59160.1 - 8.5e-06 25.9 0.0 2e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Kinesin PF00225.23 KXH59161.1 - 4.3e-56 190.2 0.0 6.6e-56 189.6 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KXH59161.1 - 5.9e-12 45.8 0.0 2.7e-09 37.1 0.0 2.4 2 0 0 2 2 2 2 Microtubule binding TSC22 PF01166.18 KXH59161.1 - 0.054 13.8 0.7 0.16 12.3 0.7 1.9 1 0 0 1 1 1 0 TSC-22/dip/bun family NRBF2 PF08961.10 KXH59161.1 - 1.6 8.3 10.3 0.036 13.7 1.6 2.4 2 0 0 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator HsbA PF12296.8 KXH59163.1 - 3.1e-26 92.1 6.0 3.1e-26 92.1 6.0 1.5 2 0 0 2 2 2 1 Hydrophobic surface binding protein A TFIIB PF00382.19 KXH59164.1 - 6.7e-34 115.8 9.8 7.6e-20 70.7 0.1 2.9 3 0 0 3 3 3 2 Transcription factor TFIIB repeat BRF1 PF07741.13 KXH59164.1 - 4.1e-25 88.1 0.9 4.1e-25 88.1 0.9 3.4 4 0 0 4 4 4 1 Brf1-like TBP-binding domain Cyclin_N PF00134.23 KXH59164.1 - 3.3e-07 30.1 0.8 0.019 14.7 0.1 2.4 2 0 0 2 2 2 2 Cyclin, N-terminal domain Thioredoxin PF00085.20 KXH59164.1 - 0.087 12.8 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin DUF1213 PF06740.12 KXH59164.1 - 6.8 7.4 7.8 3.3 8.4 2.2 2.9 1 1 2 3 3 2 0 Protein of unknown function (DUF1213) DUF1349 PF07081.11 KXH59165.1 - 8.5e-28 97.3 0.9 1e-27 97.0 0.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) MARVEL PF01284.23 KXH59166.1 - 1.1 9.3 11.1 1.6 8.7 11.1 1.4 1 1 0 1 1 1 0 Membrane-associating domain Peptidase_S24 PF00717.23 KXH59167.1 - 2e-07 30.8 0.0 3e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase S24-like DHHC PF01529.20 KXH59168.1 - 7.6 6.7 9.2 1.4e+02 2.5 0.0 3.2 2 1 0 2 2 2 0 DHHC palmitoyltransferase BTB PF00651.31 KXH59169.1 - 2.3e-07 31.0 0.0 6e-07 29.7 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain Rubella_E2 PF05749.11 KXH59169.1 - 0.015 14.8 2.4 0.033 13.6 0.1 2.1 2 0 0 2 2 2 0 Rubella membrane glycoprotein E2 Abhydrolase_1 PF00561.20 KXH59170.1 - 1.8e-09 37.7 0.0 5.9e-09 35.9 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXH59170.1 - 5.9e-08 33.6 3.2 1.7e-06 28.8 3.2 2.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXH59170.1 - 1.6e-05 24.3 0.0 0.0021 17.4 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 ATP-synt_E PF05680.12 KXH59170.1 - 0.11 12.9 0.0 0.69 10.3 0.0 2.4 2 0 0 2 2 2 0 ATP synthase E chain DLH PF01738.18 KXH59170.1 - 0.2 11.2 0.0 0.35 10.4 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family FA_hydroxylase PF04116.13 KXH59171.1 - 1.6e-09 38.2 1.7 1.6e-09 38.2 1.7 1.9 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF3808 PF10300.9 KXH59172.1 - 1.1e-129 433.2 0.6 1.4e-129 433.0 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_19 PF14559.6 KXH59172.1 - 0.0012 19.3 9.6 0.18 12.3 0.7 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KXH59172.1 - 0.012 15.7 6.6 11 6.4 0.0 5.8 5 0 0 5 5 5 0 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 KXH59172.1 - 0.015 15.0 3.7 0.017 14.8 1.9 2.0 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_10 PF13374.6 KXH59172.1 - 0.062 13.2 3.7 0.58 10.1 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 KXH59172.1 - 0.81 10.0 0.0 0.81 10.0 0.0 4.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 KXH59172.1 - 0.85 9.8 3.0 6.7 7.0 0.1 3.7 3 1 0 3 3 3 0 Tetratricopeptide repeat PTS_IIA PF02255.16 KXH59172.1 - 1.1 9.4 6.0 3.3 7.8 0.3 3.7 2 1 1 3 3 3 0 PTS system, Lactose/Cellobiose specific IIA subunit TPR_16 PF13432.6 KXH59172.1 - 1.3 9.7 10.4 2.7 8.7 0.1 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.14 KXH59172.1 - 1.4 9.8 0.0 1.4 9.8 0.0 3.7 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KXH59172.1 - 2.5 9.2 15.8 10 7.2 0.0 6.0 6 1 1 7 7 7 0 Tetratricopeptide repeat UQ_con PF00179.26 KXH59173.1 - 1.2e-42 144.9 0.0 1.4e-42 144.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KXH59173.1 - 0.00044 20.0 0.0 0.00061 19.5 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 KXH59173.1 - 0.017 15.0 0.0 0.027 14.3 0.0 1.3 1 0 0 1 1 1 0 UEV domain RWD PF05773.22 KXH59173.1 - 0.088 13.1 0.0 0.11 12.8 0.0 1.4 1 1 0 1 1 1 0 RWD domain DUF4597 PF15366.6 KXH59173.1 - 0.13 12.0 0.2 0.24 11.2 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4597) RabGAP-TBC PF00566.18 KXH59174.1 - 4.2e-12 46.2 0.1 7.5e-12 45.4 0.1 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Candida_ALS PF05792.13 KXH59182.1 - 3.7e-06 27.4 4.1 3.7e-06 27.4 4.1 43.9 42 2 1 43 43 43 2 Candida agglutinin-like (ALS) Globin PF00042.22 KXH59183.1 - 5e-07 30.3 0.0 9.3e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Globin NAD_binding_1 PF00175.21 KXH59183.1 - 7.7e-06 26.5 0.0 2.4e-05 24.9 0.0 1.9 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KXH59183.1 - 6.8e-05 23.2 0.0 0.00011 22.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 KXH59183.1 - 0.0065 16.6 0.0 0.032 14.4 0.0 2.1 3 0 0 3 3 3 1 Ferric reductase NAD binding domain Protoglobin PF11563.8 KXH59183.1 - 0.14 12.1 0.0 0.29 11.0 0.0 1.6 1 1 0 1 1 1 0 Protoglobin DAO PF01266.24 KXH59184.1 - 1.1e-10 41.7 0.0 1.2e-10 41.5 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXH59184.1 - 3.3e-05 24.0 0.0 4e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KXH59184.1 - 0.00034 19.9 0.0 0.00041 19.7 0.0 1.1 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 KXH59184.1 - 0.00088 18.6 0.0 0.00098 18.4 0.0 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXH59184.1 - 0.0017 18.3 0.0 0.0021 18.1 0.0 1.1 1 0 0 1 1 1 1 FAD-NAD(P)-binding MCRA PF06100.11 KXH59184.1 - 0.039 12.7 0.0 0.047 12.5 0.0 1.0 1 0 0 1 1 1 0 MCRA family K_oxygenase PF13434.6 KXH59184.1 - 0.08 12.1 0.0 0.088 11.9 0.0 1.1 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) GAIN_A PF18619.1 KXH59201.1 - 1.6 9.0 4.8 2 8.7 0.1 2.7 2 2 0 2 2 2 0 GPCR-Autoproteolysis-INducing (GAIN) subdomain A Ribosomal_L37ae PF01780.19 KXH59219.1 - 4.9e-41 138.7 8.6 5.4e-41 138.6 8.6 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family zf-RING_13 PF17977.1 KXH59219.1 - 0.039 14.1 2.7 0.055 13.6 2.7 1.2 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain C1_2 PF03107.16 KXH59219.1 - 0.045 14.1 2.3 2.7 8.4 0.1 2.1 1 1 1 2 2 2 0 C1 domain Rep_fac-A_C PF08646.10 KXH59219.1 - 0.074 12.8 0.5 0.1 12.3 0.5 1.3 1 0 0 1 1 1 0 Replication factor-A C terminal domain DUF1451 PF07295.11 KXH59219.1 - 0.1 12.6 1.0 0.14 12.1 1.0 1.2 1 0 0 1 1 1 0 Zinc-ribbon containing domain Zn_Tnp_IS1595 PF12760.7 KXH59219.1 - 0.11 12.4 3.4 0.19 11.7 3.4 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-BED PF02892.15 KXH59219.1 - 0.91 9.6 5.8 2.9 8.0 0.8 2.2 1 1 1 2 2 2 0 BED zinc finger zf_C2HC_14 PF18574.1 KXH59219.1 - 0.94 9.3 0.2 0.94 9.3 0.2 2.5 2 1 0 2 2 2 0 C2HC Zing finger domain Sacchrp_dh_NADP PF03435.18 KXH59220.1 - 6.7e-14 52.3 0.0 1.5e-13 51.1 0.0 1.6 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain DUF155 PF02582.14 KXH59221.1 - 2.9e-53 180.5 0.2 4.4e-53 180.0 0.2 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 HMG_box PF00505.19 KXH59222.1 - 1.9e-12 47.4 2.0 4.5e-12 46.2 2.0 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KXH59222.1 - 3.6e-06 27.5 3.4 3.6e-06 27.5 3.4 2.2 2 0 0 2 2 2 1 HMG-box domain HAUS4 PF14735.6 KXH59222.1 - 0.04 13.6 0.0 0.04 13.6 0.0 1.6 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 4 SlyX PF04102.12 KXH59222.1 - 0.44 11.2 8.8 0.66 10.6 0.3 3.4 2 1 1 3 3 3 0 SlyX ALMT PF11744.8 KXH59222.1 - 6.4 5.5 4.7 19 4.0 0.0 2.1 2 0 0 2 2 2 0 Aluminium activated malate transporter Cpn60_TCP1 PF00118.24 KXH59223.1 - 3.4e-151 504.2 6.1 3.8e-151 504.1 6.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family EAL PF00563.20 KXH59223.1 - 0.0016 18.0 0.0 0.0036 16.8 0.0 1.5 1 0 0 1 1 1 1 EAL domain TetR_C_14 PF17754.1 KXH59223.1 - 0.014 15.4 0.0 1.5 8.8 0.0 2.5 2 0 0 2 2 2 0 MftR C-terminal domain PP1_inhibitor PF05361.12 KXH59223.1 - 0.053 13.5 0.2 0.26 11.3 0.2 2.2 2 1 1 3 3 3 0 PKC-activated protein phosphatase-1 inhibitor PrpR_N PF06506.11 KXH59223.1 - 0.053 13.1 0.1 0.2 11.2 0.1 2.0 2 0 0 2 2 2 0 Propionate catabolism activator BBE PF08031.12 KXH59224.1 - 1.9e-05 24.7 0.2 3.7e-05 23.7 0.2 1.4 1 0 0 1 1 1 1 Berberine and berberine like Pyr_redox_2 PF07992.14 KXH59225.1 - 1.1e-21 77.3 0.0 3.6e-17 62.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KXH59225.1 - 3.8e-18 65.2 0.9 4.2e-16 58.5 0.2 2.4 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KXH59225.1 - 1.4e-13 50.8 0.0 4e-12 46.0 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXH59225.1 - 3.6e-10 39.9 0.2 1.2e-08 35.0 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KXH59225.1 - 9.4e-09 34.9 0.1 3.7e-07 29.6 0.0 2.3 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KXH59225.1 - 1.4e-05 25.1 1.1 0.34 10.9 0.0 4.0 3 1 0 4 4 4 2 FAD-NAD(P)-binding Pyr_redox PF00070.27 KXH59225.1 - 4.5e-05 23.9 1.2 0.19 12.3 0.2 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXH59225.1 - 5.3e-05 23.0 0.2 0.0052 16.4 0.0 3.3 2 1 0 3 3 3 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KXH59225.1 - 0.00019 20.6 0.1 0.076 12.0 0.1 3.5 3 1 0 3 3 3 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 KXH59225.1 - 0.0022 17.2 0.7 0.0034 16.5 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 KXH59225.1 - 0.0032 16.8 1.4 0.27 10.4 0.1 3.0 3 0 0 3 3 3 1 Thi4 family GIDA PF01134.22 KXH59225.1 - 0.0067 15.6 0.1 1 8.4 0.1 3.0 3 0 0 3 3 3 1 Glucose inhibited division protein A Amino_oxidase PF01593.24 KXH59225.1 - 0.022 14.1 0.0 29 3.8 0.0 3.3 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase NAD_binding_7 PF13241.6 KXH59225.1 - 0.085 13.3 0.0 25 5.4 0.0 2.6 2 0 0 2 2 2 0 Putative NAD(P)-binding HI0933_like PF03486.14 KXH59225.1 - 0.22 10.2 3.0 2 7.0 0.1 3.6 5 0 0 5 5 5 0 HI0933-like protein FMO-like PF00743.19 KXH59226.1 - 1e-11 44.0 0.0 4.6e-11 41.8 0.0 1.8 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KXH59226.1 - 2.9e-07 30.1 0.0 7.6e-07 28.7 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXH59226.1 - 6.2e-07 28.9 0.0 5.6e-05 22.5 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXH59226.1 - 6.5e-05 22.2 0.0 0.00011 21.5 0.0 1.2 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 KXH59226.1 - 0.033 14.7 0.0 0.075 13.6 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 KXH59226.1 - 0.095 12.0 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_N PF08240.12 KXH59227.1 - 2e-29 101.7 0.3 3.3e-29 100.9 0.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXH59227.1 - 1.1e-17 64.3 2.4 1.8e-17 63.5 2.4 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXH59227.1 - 6.6e-08 33.7 0.0 1.1e-07 33.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Sacchrp_dh_NADP PF03435.18 KXH59227.1 - 0.045 14.0 0.4 0.068 13.4 0.4 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 KXH59227.1 - 0.061 13.6 0.2 0.1 12.9 0.2 1.4 1 0 0 1 1 1 0 TrkA-N domain HMGL-like PF00682.19 KXH59228.1 - 1.6e-46 159.0 0.0 2e-46 158.7 0.0 1.1 1 0 0 1 1 1 1 HMGL-like ECH_1 PF00378.20 KXH59228.1 - 3e-35 121.7 0.0 5.4e-35 120.9 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXH59228.1 - 5.5e-24 85.3 0.0 8.4e-24 84.7 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ADH_N PF08240.12 KXH59229.1 - 1.5e-05 24.8 0.0 2.7e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXH59229.1 - 0.0001 22.3 0.2 0.00043 20.3 0.0 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase DUF2154 PF09922.9 KXH59229.1 - 0.02 14.8 0.0 0.035 14.0 0.0 1.4 1 0 0 1 1 1 0 Cell wall-active antibiotics response 4TMS YvqF Acyl-CoA_dh_1 PF00441.24 KXH59230.1 - 5.1e-35 120.9 2.0 5.1e-35 120.9 2.0 1.5 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KXH59230.1 - 7.6e-25 87.8 0.0 1.6e-24 86.8 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KXH59230.1 - 8.2e-19 67.6 0.0 1.4e-18 66.9 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KXH59230.1 - 5.7e-12 46.1 0.1 1e-11 45.2 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Mito_carr PF00153.27 KXH59231.1 - 2.2e-55 184.6 1.1 8.7e-19 67.3 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Cation_ATPase PF13246.6 KXH59231.1 - 0.09 12.9 0.0 0.18 11.9 0.0 1.5 1 1 0 1 1 1 0 Cation transport ATPase (P-type) adh_short PF00106.25 KXH59232.1 - 6.1e-30 104.1 0.0 7.7e-30 103.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXH59232.1 - 6.1e-21 75.0 0.0 8.2e-21 74.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH59232.1 - 0.0026 17.7 0.0 0.01 15.8 0.0 1.8 1 1 0 1 1 1 1 KR domain FAD_binding_3 PF01494.19 KXH59233.1 - 1.4e-09 37.7 0.0 2.2e-08 33.8 0.0 2.2 1 1 0 2 2 2 1 FAD binding domain Aldedh PF00171.22 KXH59234.1 - 3.7e-120 401.6 0.3 8.1e-105 351.0 0.4 2.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family DUF1487 PF07368.11 KXH59234.1 - 0.0016 17.9 0.0 0.57 9.6 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) MFS_1 PF07690.16 KXH59235.1 - 1.2e-29 103.4 35.4 1.2e-29 103.4 35.4 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.18 KXH59236.1 - 4.8e-20 71.7 0.1 8.2e-20 70.9 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH59236.1 - 1.9e-06 27.9 8.2 5.1e-06 26.5 8.2 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.24 KXH59237.1 - 2e-70 237.9 19.8 2.3e-70 237.7 19.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH59237.1 - 2.4e-24 85.9 38.8 3e-16 59.3 17.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4131 PF13567.6 KXH59237.1 - 0.36 10.5 0.0 0.36 10.5 0.0 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF4131) CstA_5TM PF13722.6 KXH59237.1 - 1.4 9.3 6.9 0.22 11.9 2.3 2.2 2 0 0 2 2 2 0 5TM C-terminal transporter carbon starvation CstA SepA PF17080.5 KXH59237.1 - 2 8.8 9.1 0.046 14.1 1.9 1.9 2 0 0 2 2 2 0 Multidrug Resistance efflux pump Zn_clus PF00172.18 KXH59238.1 - 6.3e-07 29.4 5.2 1.1e-06 28.6 5.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXH59238.1 - 0.00024 20.2 0.2 0.00033 19.8 0.2 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain AMP-binding PF00501.28 KXH59239.1 - 2.2e-86 290.1 0.0 2.9e-86 289.7 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme adh_short PF00106.25 KXH59240.1 - 4.6e-32 111.1 1.0 5.8e-32 110.7 1.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXH59240.1 - 6e-30 104.5 2.0 7.2e-30 104.3 2.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH59240.1 - 1.5e-10 41.3 2.8 2e-09 37.6 2.7 2.1 1 1 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 KXH59240.1 - 0.00078 18.5 0.3 0.0015 17.6 0.1 1.5 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KXH59240.1 - 0.17 11.3 0.3 0.28 10.6 0.3 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Cyclase PF04199.13 KXH59241.1 - 8.9e-11 42.2 0.0 1.6e-10 41.4 0.0 1.4 1 1 0 1 1 1 1 Putative cyclase HNH_2 PF13391.6 KXH59242.1 - 1.6e-07 31.4 0.0 4e-07 30.1 0.0 1.7 1 0 0 1 1 1 1 HNH endonuclease DUF3328 PF11807.8 KXH59243.1 - 9.4e-43 146.5 0.0 1.3e-42 146.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.8 KXH59245.1 - 1e-20 74.5 2.2 1.9e-20 73.6 2.2 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) 2OG-FeII_Oxy_3 PF13640.6 KXH59246.1 - 8.5e-09 36.2 0.0 1.4e-08 35.5 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Lbh PF15317.6 KXH59247.1 - 1.9 9.4 7.7 44 5.0 0.1 5.0 1 1 7 8 8 8 0 Cardiac transcription factor regulator, Developmental protein PH_10 PF15411.6 KXH59248.1 - 9.4e-30 103.4 0.5 1.6e-29 102.6 0.5 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain VWA PF00092.28 KXH59248.1 - 2.8e-13 50.5 0.0 4.7e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 KXH59248.1 - 2.1e-09 37.5 0.2 1e-08 35.3 0.2 2.1 1 1 0 1 1 1 1 von Willebrand factor type A domain zf-RING_2 PF13639.6 KXH59248.1 - 0.00087 19.6 5.7 0.0015 18.8 5.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KXH59248.1 - 0.0078 16.2 5.4 0.013 15.4 5.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain PH PF00169.29 KXH59248.1 - 0.017 15.6 0.0 0.039 14.4 0.0 1.5 1 0 0 1 1 1 0 PH domain zf-C3HC4_2 PF13923.6 KXH59248.1 - 0.059 13.2 4.5 0.11 12.4 4.5 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KXH59248.1 - 0.063 12.9 6.9 0.012 15.2 3.2 1.6 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-rbx1 PF12678.7 KXH59248.1 - 0.065 13.5 2.6 0.15 12.4 2.6 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING-like PF08746.11 KXH59248.1 - 0.086 13.2 4.3 0.16 12.3 4.3 1.4 1 0 0 1 1 1 0 RING-like domain zf-RING_11 PF17123.5 KXH59248.1 - 0.11 12.3 4.2 0.21 11.4 4.2 1.5 1 0 0 1 1 1 0 RING-like zinc finger zf-C3HC4 PF00097.25 KXH59248.1 - 0.12 12.3 5.4 0.21 11.5 5.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF1147 PF06615.11 KXH59248.1 - 0.15 12.1 0.4 0.42 10.7 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1147) zf-C3H2C3 PF17122.5 KXH59248.1 - 4.2 7.5 4.9 8.7 6.5 4.9 1.6 1 0 0 1 1 1 0 Zinc-finger MFS_1 PF07690.16 KXH59250.1 - 1.1e-29 103.5 28.6 5.1e-29 101.3 28.3 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily U3_snoRNA_assoc PF08297.11 KXH59251.1 - 3e-15 56.7 3.1 3e-15 56.7 3.1 4.6 2 1 2 4 4 4 1 U3 snoRNA associated TFIIA PF03153.13 KXH59251.1 - 5.4 6.9 25.6 7 6.5 25.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TPR_2 PF07719.17 KXH59252.1 - 0.019 15.0 3.6 0.32 11.2 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 KXH59252.1 - 0.16 11.8 1.9 6.5 6.7 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Glyco_hydro_35 PF01301.19 KXH59253.1 - 1.5e-81 274.5 3.4 2.2e-81 273.9 3.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 KXH59253.1 - 8.8e-62 206.7 1.4 1.8e-33 115.5 0.0 2.7 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.9 KXH59253.1 - 1.6e-51 174.7 1.8 3.5e-51 173.6 1.8 1.6 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.6 KXH59253.1 - 6.5e-25 86.5 0.1 2.1e-23 81.7 0.0 2.7 3 0 0 3 3 3 1 Beta-galactosidase, domain 3 Glyco_hydro_42 PF02449.15 KXH59253.1 - 1e-05 25.0 0.0 0.00057 19.3 0.1 2.9 1 1 1 2 2 2 1 Beta-galactosidase Cellulase PF00150.18 KXH59253.1 - 8.2e-05 22.2 0.2 0.00072 19.1 0.0 2.4 2 1 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) 6PGD PF00393.19 KXH59285.1 - 1.3e-128 428.4 0.0 1.8e-128 428.0 0.0 1.2 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 KXH59285.1 - 1.9e-49 167.8 0.0 2.9e-49 167.3 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase DNA_pol3_beta PF00712.19 KXH59285.1 - 0.014 15.6 0.0 0.034 14.3 0.0 1.6 1 0 0 1 1 1 0 DNA polymerase III beta subunit, N-terminal domain PGK PF00162.19 KXH59285.1 - 0.043 12.8 0.0 0.068 12.1 0.0 1.3 1 0 0 1 1 1 0 Phosphoglycerate kinase NAD_binding_11 PF14833.6 KXH59285.1 - 0.046 14.0 0.0 0.17 12.1 0.0 2.0 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 3HCDH_N PF02737.18 KXH59285.1 - 0.24 11.2 0.6 1.2 9.0 0.1 2.0 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SWI-SNF_Ssr4 PF08549.10 KXH59286.1 - 1e-289 963.3 8.1 1.6e-289 962.6 8.1 1.3 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1750) Vir_act_alpha_C PF10400.9 KXH59286.1 - 2.1 9.1 5.6 23 5.8 1.7 2.6 2 0 0 2 2 2 0 Virulence activator alpha C-term GPI-anchored PF10342.9 KXH59287.1 - 2.4e-07 31.4 0.0 6.1e-07 30.1 0.0 1.7 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Glutaredoxin PF00462.24 KXH59288.1 - 6.1e-19 68.0 0.0 5.1e-18 65.0 0.0 2.2 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.20 KXH59288.1 - 6.3e-14 51.8 0.0 1.5e-13 50.6 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 KXH59288.1 - 0.014 15.7 0.0 5.9 7.3 0.0 2.7 1 1 1 2 2 2 0 Thioredoxin-like HyaE PF07449.11 KXH59288.1 - 0.035 14.1 0.0 0.15 12.0 0.0 2.0 2 1 0 2 2 2 0 Hydrogenase-1 expression protein HyaE Thioredoxin_3 PF13192.6 KXH59288.1 - 0.093 12.8 0.0 0.66 10.1 0.0 2.4 2 2 0 2 2 2 0 Thioredoxin domain SH3_9 PF14604.6 KXH59289.1 - 1.5e-28 98.4 4.4 3.4e-14 52.4 0.5 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 KXH59289.1 - 2.9e-26 90.8 4.6 1.2e-12 47.3 0.3 2.4 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 KXH59289.1 - 2.6e-17 62.2 0.0 4.3e-07 29.5 0.0 3.0 3 0 0 3 3 3 2 Variant SH3 domain Cofilin_ADF PF00241.20 KXH59289.1 - 9.1e-15 54.5 0.0 1.7e-14 53.7 0.0 1.4 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein DUF3873 PF12989.7 KXH59289.1 - 0.11 12.9 0.0 2.5 8.5 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function, B. Theta Gene description (DUF3873) CYSTM PF12734.7 KXH59290.1 - 0.00051 20.3 46.0 0.00051 20.3 46.0 4.5 2 1 1 3 3 3 1 Cysteine-rich TM module stress tolerance Glyco_hydro_38C PF07748.13 KXH59303.1 - 2.6e-52 178.0 0.0 4.7e-52 177.2 0.0 1.4 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 KXH59303.1 - 4.8e-12 45.9 0.0 9.3e-12 44.9 0.0 1.4 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 KXH59303.1 - 1.6e-10 41.0 0.0 6.7e-10 38.9 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain WSC PF01822.19 KXH59304.1 - 1.6e-11 44.2 8.8 1.6e-11 44.2 8.8 2.0 2 0 0 2 2 2 1 WSC domain SKG6 PF08693.10 KXH59304.1 - 0.00027 20.3 1.3 0.00068 19.0 1.3 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Trp_oprn_chp PF09534.10 KXH59304.1 - 0.0029 17.4 0.5 0.0083 15.9 0.5 1.9 1 1 0 1 1 1 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) PTP_tm PF18861.1 KXH59304.1 - 0.0043 17.1 0.0 0.0058 16.6 0.0 1.3 1 0 0 1 1 1 1 Transmembrane domain of protein tyrosine phosphatase, receptor type J Gram_pos_anchor PF00746.21 KXH59304.1 - 0.011 15.7 0.1 0.011 15.7 0.1 1.8 2 0 0 2 2 2 0 LPXTG cell wall anchor motif Adeno_E3_CR2 PF02439.15 KXH59304.1 - 0.03 14.1 0.0 0.066 13.0 0.0 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF4366 PF14283.6 KXH59304.1 - 0.065 13.3 0.3 0.2 11.7 0.3 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) DUF2207 PF09972.9 KXH59304.1 - 0.076 11.8 0.0 0.1 11.3 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) EphA2_TM PF14575.6 KXH59304.1 - 0.079 13.9 0.0 0.18 12.7 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF1180 PF06679.12 KXH59304.1 - 0.16 12.3 5.5 0.28 11.6 5.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Podoplanin PF05808.11 KXH59304.1 - 1.1 9.3 18.6 3.4 7.8 18.7 1.7 1 1 0 1 1 1 0 Podoplanin TMEM154 PF15102.6 KXH59304.1 - 3.3 7.6 10.9 4.6 7.1 7.7 2.4 2 1 0 2 2 2 0 TMEM154 protein family NAP PF00956.18 KXH59309.1 - 8.4e-101 336.7 10.3 8.4e-101 336.7 10.3 1.5 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) Striatin PF08232.12 KXH59309.1 - 0.022 15.3 1.8 0.022 15.3 1.8 2.7 2 1 0 2 2 2 0 Striatin family RNA_pol_3_Rpc31 PF11705.8 KXH59309.1 - 9.5 6.4 33.6 1.5 9.0 19.4 2.5 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 2-Hacid_dh_C PF02826.19 KXH59310.1 - 1.1e-53 181.3 0.0 1.8e-53 180.6 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KXH59310.1 - 5.4e-37 126.5 0.2 7.3e-37 126.0 0.2 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KXH59310.1 - 5.2e-06 26.7 0.4 1.5e-05 25.3 0.4 1.7 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.21 KXH59310.1 - 0.0006 19.9 0.1 0.0014 18.8 0.1 1.5 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain IlvN PF07991.12 KXH59310.1 - 0.0025 17.4 0.3 0.021 14.4 0.1 2.1 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain XdhC_C PF13478.6 KXH59310.1 - 0.018 15.5 0.0 0.075 13.5 0.0 2.0 2 0 0 2 2 2 0 XdhC Rossmann domain 3HCDH_N PF02737.18 KXH59310.1 - 0.034 14.0 2.9 1.1 9.1 0.6 2.6 2 1 1 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ACT PF01842.25 KXH59310.1 - 0.058 13.2 0.3 0.18 11.6 0.1 2.0 2 0 0 2 2 2 0 ACT domain Myosin_head PF00063.21 KXH59311.1 - 7.5e-259 860.5 0.2 1.3e-258 859.8 0.2 1.4 1 0 0 1 1 1 1 Myosin head (motor domain) DIL PF01843.19 KXH59311.1 - 2.5e-26 92.0 2.7 2.5e-26 92.0 2.7 2.7 2 0 0 2 2 2 1 DIL domain IQ PF00612.27 KXH59311.1 - 1.1e-19 68.3 31.8 3.8e-05 23.1 1.8 6.9 6 0 0 6 6 6 5 IQ calmodulin-binding motif GAS PF13851.6 KXH59311.1 - 0.00043 19.7 29.7 0.00063 19.2 14.7 2.7 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding Myosin_N PF02736.19 KXH59311.1 - 0.00064 19.5 1.9 0.00064 19.5 1.9 2.0 2 0 0 2 2 2 1 Myosin N-terminal SH3-like domain AAA_16 PF13191.6 KXH59311.1 - 0.0024 18.3 0.6 0.0098 16.3 0.0 2.4 2 0 0 2 2 1 1 AAA ATPase domain AAA_22 PF13401.6 KXH59311.1 - 0.0027 18.0 0.0 0.014 15.7 0.0 2.2 1 0 0 1 1 1 1 AAA domain CALCOCO1 PF07888.11 KXH59311.1 - 0.0029 16.5 25.8 0.0057 15.6 25.8 1.4 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like FlaC_arch PF05377.11 KXH59311.1 - 0.038 14.4 0.2 0.038 14.4 0.2 4.4 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) Baculo_PEP_C PF04513.12 KXH59311.1 - 0.084 12.9 13.6 0.042 13.9 6.5 2.9 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_13 PF13166.6 KXH59311.1 - 0.093 11.4 14.4 0.2 10.2 14.4 1.5 1 0 0 1 1 1 0 AAA domain TMF_TATA_bd PF12325.8 KXH59311.1 - 0.23 11.7 24.9 0.29 11.4 8.4 3.4 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding Leu_zip PF15294.6 KXH59311.1 - 0.5 9.8 20.3 2 7.8 20.2 2.0 1 1 0 1 1 1 0 Leucine zipper DUF5407 PF17401.2 KXH59311.1 - 0.57 10.5 2.4 1.2 9.4 1.1 2.3 2 0 0 2 2 1 0 Family of unknown function (DUF5407) Sec34 PF04136.15 KXH59311.1 - 0.6 10.0 14.1 0.17 11.8 4.3 2.6 1 1 1 2 2 2 0 Sec34-like family DUF812 PF05667.11 KXH59311.1 - 0.73 8.6 28.6 2.7 6.8 28.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF812) ABC_tran PF00005.27 KXH59311.1 - 0.86 10.1 4.1 1.9 9.0 0.0 3.0 2 0 0 2 2 2 0 ABC transporter Phage_GP20 PF06810.11 KXH59311.1 - 0.92 9.3 17.1 0.091 12.6 3.1 3.3 1 1 2 3 3 3 0 Phage minor structural protein GP20 DUF3450 PF11932.8 KXH59311.1 - 1 8.6 29.5 1.6 8.0 15.0 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) ATG16 PF08614.11 KXH59311.1 - 1 9.5 31.8 2.9 8.1 16.7 2.8 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) FPP PF05911.11 KXH59311.1 - 1.2 7.2 23.2 0.47 8.6 3.8 2.2 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil FUSC PF04632.12 KXH59311.1 - 1.2 7.6 16.6 0.11 11.0 11.4 1.6 1 1 0 1 1 1 0 Fusaric acid resistance protein family DUF1664 PF07889.12 KXH59311.1 - 1.4 9.0 13.8 12 6.0 0.4 2.8 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) DUF4665 PF15679.5 KXH59311.1 - 1.6 9.4 13.2 1.3 9.7 3.3 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4665) KASH_CCD PF14662.6 KXH59311.1 - 3 7.6 31.9 5.6 6.8 16.6 2.8 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH APG6_N PF17675.1 KXH59311.1 - 5.3 7.6 32.3 1.8 9.1 23.2 2.9 1 1 1 2 2 2 0 Apg6 coiled-coil region BRE1 PF08647.11 KXH59311.1 - 7 6.8 25.6 0.75 9.9 4.9 3.3 1 1 2 3 3 3 0 BRE1 E3 ubiquitin ligase CENP-F_leu_zip PF10473.9 KXH59311.1 - 9.9 6.2 30.7 2 8.4 5.5 2.7 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_18 PF13238.6 KXH59312.1 - 2.5e-28 99.2 0.2 4.5e-28 98.4 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 KXH59312.1 - 2.2e-08 34.6 0.0 1.4e-07 32.0 0.0 2.1 1 1 1 2 2 2 1 AAA domain ADK PF00406.22 KXH59312.1 - 1.1e-05 25.6 0.0 0.0039 17.3 0.0 2.2 2 0 0 2 2 2 1 Adenylate kinase AAA_33 PF13671.6 KXH59312.1 - 1.3e-05 25.3 0.1 0.0066 16.6 0.0 2.4 1 1 0 2 2 2 2 AAA domain AAA PF00004.29 KXH59312.1 - 1.8e-05 25.2 0.0 0.0022 18.4 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 KXH59312.1 - 4.9e-05 23.6 0.1 0.00054 20.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain Thymidylate_kin PF02223.17 KXH59312.1 - 0.00012 21.8 0.1 0.47 10.1 0.0 2.1 2 0 0 2 2 2 2 Thymidylate kinase AAA_16 PF13191.6 KXH59312.1 - 0.0006 20.2 0.2 0.0018 18.6 0.2 1.9 1 1 0 1 1 1 1 AAA ATPase domain NTPase_1 PF03266.15 KXH59312.1 - 0.00066 19.6 0.1 0.0015 18.4 0.0 1.7 2 0 0 2 2 2 1 NTPase AAA_22 PF13401.6 KXH59312.1 - 0.00085 19.6 0.2 0.003 17.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain Hydin_ADK PF17213.3 KXH59312.1 - 0.0014 18.9 0.0 0.0029 17.9 0.0 1.5 2 0 0 2 2 2 1 Hydin Adenylate kinase-like domain KTI12 PF08433.10 KXH59312.1 - 0.0019 17.7 0.0 0.0059 16.1 0.0 1.7 2 0 0 2 2 2 1 Chromatin associated protein KTI12 Viral_helicase1 PF01443.18 KXH59312.1 - 0.005 16.6 0.0 0.0091 15.8 0.0 1.5 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase SKI PF01202.22 KXH59312.1 - 0.0061 16.7 0.0 4.1 7.5 0.0 2.1 2 0 0 2 2 2 2 Shikimate kinase RNA_helicase PF00910.22 KXH59312.1 - 0.014 15.7 0.0 0.026 14.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase SRP54 PF00448.22 KXH59312.1 - 0.015 15.0 0.0 0.024 14.3 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ATP_bind_1 PF03029.17 KXH59312.1 - 0.015 15.1 0.3 0.038 13.8 0.0 1.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_19 PF13245.6 KXH59312.1 - 0.022 15.1 1.7 0.099 13.0 0.0 2.3 3 0 0 3 3 2 0 AAA domain dNK PF01712.19 KXH59312.1 - 0.023 14.6 0.4 4.6 7.0 0.0 2.2 1 1 0 2 2 2 0 Deoxynucleoside kinase AAA_24 PF13479.6 KXH59312.1 - 0.023 14.4 0.0 0.07 12.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 KXH59312.1 - 0.027 14.5 0.0 0.061 13.3 0.0 1.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 KXH59312.1 - 0.06 13.4 0.0 0.2 11.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain DnaB_2 PF07261.11 KXH59312.1 - 0.063 13.0 0.3 0.13 12.0 0.3 1.5 1 0 0 1 1 1 0 Replication initiation and membrane attachment AAA_30 PF13604.6 KXH59312.1 - 0.1 12.3 1.3 0.95 9.2 0.3 2.3 1 1 1 2 2 2 0 AAA domain MeaB PF03308.16 KXH59312.1 - 0.16 10.9 0.0 0.28 10.1 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Ham1p_like PF01725.16 KXH59313.1 - 2.2e-56 190.8 0.0 2.5e-56 190.6 0.0 1.0 1 0 0 1 1 1 1 Ham1 family Peptidase_C78 PF07910.13 KXH59314.1 - 7.3e-69 231.5 0.0 9.7e-69 231.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C78 Hist_deacetyl PF00850.19 KXH59314.1 - 0.0031 17.0 0.0 0.0044 16.5 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain zf-Di19 PF05605.12 KXH59314.1 - 0.034 14.5 0.8 0.079 13.3 0.1 2.0 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding RNF220 PF15926.5 KXH59314.1 - 0.087 12.4 0.3 0.18 11.4 0.1 1.6 2 0 0 2 2 2 0 E3 ubiquitin-protein ligase RNF220 PRP21_like_P PF12230.8 KXH59314.1 - 0.14 12.0 0.1 0.24 11.2 0.1 1.4 1 0 0 1 1 1 0 Pre-mRNA splicing factor PRP21 like protein RasGEF PF00617.19 KXH59369.1 - 1.2e-59 201.5 0.0 2.1e-59 200.7 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KXH59369.1 - 2.9e-28 98.2 0.7 6e-28 97.2 0.7 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.28 KXH59369.1 - 1.8e-15 56.3 0.1 3.7e-15 55.3 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KXH59369.1 - 4.1e-14 52.2 0.2 8.6e-14 51.1 0.2 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KXH59369.1 - 2.7e-13 49.4 0.1 5.8e-13 48.3 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.26 KXH59369.1 - 0.073 13.2 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 WW domain Lipase_GDSL_2 PF13472.6 KXH59371.1 - 1.1e-09 39.0 0.0 1.8e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KXH59371.1 - 0.00011 22.3 0.0 0.0002 21.4 0.0 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase SPX PF03105.19 KXH59372.1 - 0.083 12.8 0.3 0.093 12.6 0.3 1.1 1 0 0 1 1 1 0 SPX domain SCA7 PF08313.12 KXH59373.1 - 6.7e-32 109.2 0.2 2.4e-31 107.4 0.2 2.0 1 0 0 1 1 1 1 SCA7, zinc-binding domain CDC45 PF02724.14 KXH59373.1 - 0.19 10.0 12.0 0.27 9.5 12.0 1.3 1 0 0 1 1 1 0 CDC45-like protein Mito_carr PF00153.27 KXH59374.1 - 1.1e-42 143.9 0.4 3.1e-14 52.7 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein zf-RING_2 PF13639.6 KXH59375.1 - 1.9e-07 31.3 15.1 3.5e-05 24.0 6.5 2.6 2 0 0 2 2 2 2 Ring finger domain zf-NOSIP PF15906.5 KXH59375.1 - 2.3e-07 30.8 0.0 1.5e-06 28.2 0.0 2.2 2 1 0 2 2 2 1 Zinc-finger of nitric oxide synthase-interacting protein zf-RING_UBOX PF13445.6 KXH59375.1 - 4.9e-07 29.7 12.1 0.002 18.1 5.6 2.9 3 0 0 3 3 3 2 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KXH59375.1 - 5.5e-06 26.1 16.9 0.0026 17.5 7.4 2.7 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXH59375.1 - 2e-05 24.5 6.7 2e-05 24.5 6.7 2.5 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KXH59375.1 - 9.4e-05 22.2 16.7 0.017 15.0 7.4 2.6 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KXH59375.1 - 0.001 19.1 16.4 0.19 11.9 1.7 2.9 2 1 0 2 2 2 2 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KXH59375.1 - 0.076 12.9 20.9 0.086 12.7 7.7 3.4 3 1 1 4 4 4 0 Prokaryotic RING finger family 4 FYVE PF01363.21 KXH59375.1 - 0.24 11.5 13.5 0.39 10.9 6.6 2.8 2 1 0 2 2 2 0 FYVE zinc finger DZR PF12773.7 KXH59375.1 - 0.27 11.3 14.0 0.057 13.4 6.2 2.7 2 0 0 2 2 2 0 Double zinc ribbon zf-RING_10 PF16685.5 KXH59375.1 - 0.64 10.2 13.9 0.27 11.4 5.1 2.7 3 0 0 3 3 3 0 zinc RING finger of MSL2 IBR PF01485.21 KXH59375.1 - 1.3 9.3 11.2 1.4 9.2 4.4 2.8 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain Acyltransferase PF01553.21 KXH59376.1 - 5.3e-14 52.0 0.0 8.1e-14 51.4 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Pkinase PF00069.25 KXH59377.1 - 4.4e-78 262.3 0.0 5.1e-78 262.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXH59377.1 - 4.5e-38 131.0 0.0 6e-38 130.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KXH59377.1 - 0.001 18.1 0.0 0.011 14.6 0.0 2.1 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KXH59377.1 - 0.011 15.1 0.1 0.019 14.3 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXH59377.1 - 0.02 14.8 0.1 0.068 13.1 0.1 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 KXH59377.1 - 0.051 12.9 0.1 0.13 11.5 0.1 1.7 1 1 1 2 2 2 0 Kinase-like Septin PF00735.18 KXH59378.1 - 1.3e-18 67.3 0.0 2.4e-14 53.3 0.0 2.1 2 0 0 2 2 2 2 Septin MMR_HSR1 PF01926.23 KXH59378.1 - 0.0006 19.9 0.0 0.0065 16.5 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KXH59378.1 - 0.011 16.1 0.1 0.032 14.6 0.1 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 KXH59378.1 - 0.03 14.6 0.1 0.083 13.2 0.1 1.7 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KXH59378.1 - 0.034 14.1 0.0 0.24 11.3 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase AAA_24 PF13479.6 KXH59378.1 - 0.089 12.5 0.1 0.96 9.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 KXH59378.1 - 0.12 12.5 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA PF00004.29 KXH59378.1 - 0.19 12.2 0.1 0.33 11.4 0.1 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 KXH59378.1 - 0.23 10.7 0.0 0.4 9.9 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin PAP_central PF04928.17 KXH59379.1 - 2.7e-108 360.7 0.0 4.1e-108 360.1 0.0 1.3 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 KXH59379.1 - 3.5e-65 218.8 5.6 2.9e-64 215.8 5.6 2.3 1 1 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 KXH59379.1 - 4.3e-09 36.6 0.0 9.7e-09 35.4 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain Nrap_D2 PF17403.2 KXH59379.1 - 0.032 14.0 0.1 0.17 11.6 0.1 2.2 3 0 0 3 3 3 0 Nrap protein PAP/OAS-like domain Polbeta PF18765.1 KXH59379.1 - 0.13 12.4 0.0 0.34 11.0 0.0 1.7 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase Tubulin_3 PF14881.6 KXH59380.1 - 9.8e-79 263.2 0.3 1.7e-78 262.5 0.3 1.4 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.9 KXH59380.1 - 3e-42 143.7 0.0 5.3e-42 142.9 0.0 1.4 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin PF00091.25 KXH59380.1 - 6.5e-07 29.7 0.0 0.0028 17.9 0.0 2.4 2 0 0 2 2 2 2 Tubulin/FtsZ family, GTPase domain PARM PF17061.5 KXH59380.1 - 0.046 13.9 1.1 0.1 12.7 1.1 1.5 1 0 0 1 1 1 0 PARM Forkhead PF00250.18 KXH59381.1 - 6e-35 119.4 1.0 1.4e-34 118.2 0.8 1.7 2 0 0 2 2 2 1 Forkhead domain FHA PF00498.26 KXH59381.1 - 1e-08 35.4 0.0 2.8e-08 34.0 0.0 1.8 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KXH59381.1 - 0.00046 20.4 0.0 0.00085 19.6 0.0 1.4 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Linker_histone PF00538.19 KXH59381.1 - 0.068 13.5 0.2 0.16 12.3 0.2 1.6 1 0 0 1 1 1 0 linker histone H1 and H5 family CLU PF13236.6 KXH59382.1 - 3.8e-77 259.1 0.0 6.8e-77 258.2 0.0 1.4 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 KXH59382.1 - 1.6e-53 181.3 0.0 1.6e-53 181.3 0.0 2.1 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.6 KXH59382.1 - 7.4e-24 83.8 11.5 2.5e-10 40.5 0.1 4.1 3 1 1 4 4 4 3 Tetratricopeptide repeat CLU_N PF15044.6 KXH59382.1 - 2.3e-23 82.4 1.3 8.4e-23 80.5 0.1 2.4 2 0 0 2 2 2 1 Mitochondrial function, CLU-N-term TPR_10 PF13374.6 KXH59382.1 - 1.3e-22 78.9 0.5 7.2e-06 25.7 0.0 5.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 KXH59382.1 - 0.00047 20.2 6.8 0.016 15.4 0.2 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 KXH59382.1 - 0.002 18.1 6.5 0.1 12.8 0.1 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat DDHD PF02862.17 KXH59382.1 - 0.0071 16.5 3.3 0.0071 16.5 3.3 2.2 2 0 0 2 2 2 1 DDHD domain DUF727 PF05303.12 KXH59382.1 - 0.0072 16.4 0.0 0.022 14.8 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF727) CDC45 PF02724.14 KXH59382.1 - 0.045 12.1 14.4 0.073 11.4 14.4 1.3 1 0 0 1 1 1 0 CDC45-like protein TPR_MalT PF17874.1 KXH59382.1 - 0.35 10.2 5.1 1.3 8.3 0.1 2.2 1 1 0 2 2 2 0 MalT-like TPR region Menin PF05053.13 KXH59382.1 - 2.5 6.4 14.7 3.9 5.7 9.7 2.2 2 0 0 2 2 2 0 Menin Nop14 PF04147.12 KXH59382.1 - 4.2 5.5 23.3 8.5 4.5 23.3 1.4 1 0 0 1 1 1 0 Nop14-like family Ferric_reduct PF01794.19 KXH59384.1 - 2.4e-24 85.8 9.0 5.8e-24 84.6 9.0 1.7 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KXH59384.1 - 3.2e-19 69.6 0.0 1.3e-16 61.1 0.0 2.4 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Yippee-Mis18 PF03226.14 KXH59384.1 - 2.2e-15 56.7 0.8 4.2e-15 55.8 0.8 1.5 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly FAD_binding_8 PF08022.12 KXH59384.1 - 2.1e-12 47.1 0.0 5.2e-11 42.6 0.0 2.4 1 1 0 1 1 1 1 FAD-binding domain RIG-I_C-RD PF11648.8 KXH59384.1 - 0.076 13.3 1.1 0.14 12.4 1.1 1.4 1 0 0 1 1 1 0 C-terminal domain of RIG-I DUF1345 PF07077.11 KXH59384.1 - 0.56 9.9 9.0 0.1 12.3 4.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1345) Nuc_sug_transp PF04142.15 KXH59385.1 - 4.6e-10 39.2 1.7 1.7e-09 37.3 1.7 1.9 1 1 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 KXH59385.1 - 1.5e-08 34.9 23.6 0.00019 21.6 5.4 2.5 2 1 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 KXH59385.1 - 3.3e-05 23.4 1.6 3.3e-05 23.4 1.6 1.7 2 0 0 2 2 2 1 Triose-phosphate Transporter family PUNUT PF16913.5 KXH59385.1 - 0.0017 17.7 0.6 0.0017 17.7 0.6 1.7 2 0 0 2 2 2 1 Purine nucleobase transmembrane transport DUF2975 PF11188.8 KXH59385.1 - 0.14 12.1 11.9 0.71 9.8 0.9 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2975) DUF423 PF04241.15 KXH59385.1 - 0.88 9.8 7.2 3.7 7.8 0.9 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF423) CRT-like PF08627.10 KXH59385.1 - 1.2 8.0 7.4 0.31 9.9 4.2 1.7 2 0 0 2 2 2 0 CRT-like, chloroquine-resistance transporter-like Gate PF07670.14 KXH59385.1 - 3.5 8.0 10.2 0.14 12.4 2.1 2.7 3 1 0 3 3 3 0 Nucleoside recognition DUF2985 PF11204.8 KXH59386.1 - 1.1e-38 131.3 1.4 1.1e-38 131.3 1.4 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2985) MFS_1 PF07690.16 KXH59454.1 - 8.9e-34 117.0 44.2 8.9e-34 117.0 44.2 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KXH59454.1 - 1.4e-13 50.2 14.7 1.4e-13 50.2 14.7 1.7 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF423 PF04241.15 KXH59454.1 - 5.5 7.3 10.3 0.078 13.2 0.8 3.0 4 0 0 4 4 4 0 Protein of unknown function (DUF423) 4HBT PF03061.22 KXH59470.1 - 3.1e-06 27.4 0.3 7.1e-06 26.3 0.2 1.6 2 0 0 2 2 2 1 Thioesterase superfamily FAD_binding_7 PF03441.14 KXH59471.1 - 8.7e-46 156.0 0.1 1.4e-45 155.3 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 KXH59471.1 - 3.6e-20 72.6 0.0 6.9e-20 71.7 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase Fungal_trans PF04082.18 KXH59473.1 - 9.7e-07 28.1 0.0 2e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain ET PF01684.16 KXH59473.1 - 0.041 14.2 0.4 0.1 13.0 0.4 1.6 1 0 0 1 1 1 0 ET module Peptidase_M43 PF05572.13 KXH59475.1 - 1.9e-11 44.1 0.0 4.4e-11 42.9 0.0 1.6 2 0 0 2 2 2 1 Pregnancy-associated plasma protein-A DUF4953 PF16313.5 KXH59475.1 - 0.00051 19.4 0.0 0.00086 18.6 0.0 1.3 1 0 0 1 1 1 1 Met-zincin Reprolysin_5 PF13688.6 KXH59475.1 - 0.0023 18.1 0.0 0.0035 17.5 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 KXH59475.1 - 0.0091 16.5 0.1 0.018 15.5 0.1 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like VWA_N PF08399.11 KXH59475.1 - 0.025 15.1 0.0 0.049 14.1 0.0 1.5 1 0 0 1 1 1 0 VWA N-terminal Peptidase_M10 PF00413.24 KXH59475.1 - 0.11 12.4 0.5 0.18 11.6 0.5 1.5 1 1 0 1 1 1 0 Matrixin Acetyltransf_9 PF13527.7 KXH59476.1 - 1.6e-06 28.2 0.1 3.8e-06 27.0 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXH59476.1 - 2.7e-05 24.4 0.0 0.00051 20.3 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_15 PF17013.5 KXH59476.1 - 0.00091 18.8 0.0 0.0014 18.1 0.0 1.2 1 0 0 1 1 1 1 Putative acetyl-transferase Acetyltransf_10 PF13673.7 KXH59476.1 - 0.0025 17.8 0.0 0.0048 16.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXH59476.1 - 0.0038 17.6 0.0 0.0077 16.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 KXH59476.1 - 0.0076 16.2 0.0 0.019 14.9 0.0 1.7 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase Phosphodiest PF01663.22 KXH59478.1 - 4.4e-90 302.8 0.3 6e-90 302.4 0.3 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Ntox33 PF15533.6 KXH59478.1 - 0.016 15.7 4.4 0.055 14.0 4.4 1.9 1 0 0 1 1 1 0 Bacterial toxin 33 Sulfatase PF00884.23 KXH59478.1 - 0.075 12.4 0.0 0.49 9.7 0.0 2.1 2 0 0 2 2 2 0 Sulfatase EF-hand_1 PF00036.32 KXH59481.1 - 0.039 13.5 0.0 2.3 7.9 0.0 2.4 2 0 0 2 2 2 0 EF hand EF-hand_6 PF13405.6 KXH59481.1 - 0.086 12.8 0.0 16 5.7 0.0 2.4 2 0 0 2 2 2 0 EF-hand domain p450 PF00067.22 KXH59500.1 - 6.7e-20 71.3 0.0 7.7e-20 71.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Acyl-CoA_dh_M PF02770.19 KXH59544.1 - 1.7e-05 24.9 0.0 3.1e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain DUF1752 PF08550.10 KXH59560.1 - 1.5e-10 40.7 7.3 1.8e-10 40.4 5.8 2.0 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF1752) GOLD_2 PF13897.6 KXH59560.1 - 0.38 11.2 2.6 0.4 11.2 0.4 2.0 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking PBP1_TM PF14812.6 KXH59560.1 - 1.6 9.2 9.3 3 8.3 3.6 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Glyco_hydro_18 PF00704.28 KXH59647.1 - 4.3e-68 230.3 0.1 5.2e-68 230.1 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 PALP PF00291.25 KXH59656.1 - 1.3e-55 188.9 2.1 1.7e-55 188.5 2.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CbeA_antitoxin PF06154.11 KXH59683.1 - 0.037 14.6 0.0 0.72 10.5 0.0 2.5 3 0 0 3 3 3 0 CbeA_antitoxin, type IV, cytoskeleton bundling-enhancing factor A Peptidase_M18 PF02127.15 KXH59690.1 - 1.6e-173 577.5 0.0 5.6e-173 575.7 0.0 1.7 1 1 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 KXH59690.1 - 5.7e-06 25.6 0.2 0.0017 17.4 0.0 2.7 3 0 0 3 3 3 2 M42 glutamyl aminopeptidase DUF3552 PF12072.8 KXH59691.1 - 0.06 12.8 2.1 0.073 12.5 2.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Androgen_recep PF02166.16 KXH59691.1 - 3.8 6.2 7.7 4.6 6.0 7.7 1.1 1 0 0 1 1 1 0 Androgen receptor Peptidase_M3 PF01432.20 KXH59700.1 - 1.7e-118 396.8 0.0 7.7e-118 394.6 0.0 1.8 1 1 0 1 1 1 1 Peptidase family M3 TauD PF02668.16 KXH59701.1 - 2.8e-62 211.0 0.3 3.4e-62 210.7 0.3 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Sugar_tr PF00083.24 KXH59702.1 - 3.8e-129 431.5 27.3 4.3e-129 431.3 27.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH59702.1 - 6.4e-23 81.2 50.0 6.5e-18 64.8 25.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily GRDP-like PF07173.12 KXH59703.1 - 6.3e-21 75.5 0.4 4.9e-15 56.4 0.1 2.6 2 0 0 2 2 2 2 Glycine-rich domain-containing protein-like Pico_P2A PF00947.19 KXH59703.1 - 1.7 8.7 4.7 11 6.0 5.0 2.0 2 0 0 2 2 2 0 Picornavirus core protein 2A DUF1524 PF07510.11 KXH59704.1 - 1.2e-08 34.9 0.0 1.5e-08 34.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1524) Glyco_hydro_16 PF00722.21 KXH59705.1 - 7.1e-43 146.1 0.3 1.4e-42 145.2 0.3 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SOG2 PF10428.9 KXH59705.1 - 0.18 11.0 8.8 0.25 10.5 8.8 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein AAA_18 PF13238.6 KXH59707.1 - 9.2e-12 45.6 0.1 6.6e-10 39.6 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KXH59707.1 - 2.7e-09 37.3 0.0 3.5e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 AAA domain SKI PF01202.22 KXH59707.1 - 2.1e-08 34.4 0.1 0.0029 17.7 0.1 2.1 2 0 0 2 2 2 2 Shikimate kinase AAA_22 PF13401.6 KXH59707.1 - 8.6e-05 22.8 0.0 0.00017 21.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KXH59707.1 - 0.00015 22.2 0.0 0.00024 21.5 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.6 KXH59707.1 - 0.00017 22.0 0.1 0.0019 18.6 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 KXH59707.1 - 0.00028 21.3 0.0 0.00055 20.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) CPT PF07931.12 KXH59707.1 - 0.001 19.0 0.0 0.0095 15.8 0.0 2.1 1 1 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_5 PF07728.14 KXH59707.1 - 0.002 18.1 0.1 0.011 15.8 0.0 2.1 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) ABC_tran PF00005.27 KXH59707.1 - 0.0032 18.0 0.0 0.004 17.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter Zeta_toxin PF06414.12 KXH59707.1 - 0.0036 16.6 0.0 0.0082 15.4 0.0 1.7 1 1 0 1 1 1 1 Zeta toxin APS_kinase PF01583.20 KXH59707.1 - 0.0043 17.0 0.0 0.0061 16.5 0.0 1.6 1 1 0 1 1 1 1 Adenylylsulphate kinase AAA_7 PF12775.7 KXH59707.1 - 0.0043 16.6 0.0 0.0071 15.9 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region CoaE PF01121.20 KXH59707.1 - 0.005 16.5 0.0 0.0096 15.6 0.0 1.5 1 0 0 1 1 1 1 Dephospho-CoA kinase RNA_helicase PF00910.22 KXH59707.1 - 0.0054 17.1 0.0 0.0085 16.5 0.0 1.3 1 0 0 1 1 1 1 RNA helicase NTPase_1 PF03266.15 KXH59707.1 - 0.0057 16.6 0.7 0.014 15.3 0.3 1.8 2 1 1 3 3 2 1 NTPase T2SSE PF00437.20 KXH59707.1 - 0.006 15.7 0.1 0.0092 15.1 0.1 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein Rad17 PF03215.15 KXH59707.1 - 0.0062 16.5 0.0 0.014 15.4 0.0 1.6 2 0 0 2 2 1 1 Rad17 P-loop domain PhoH PF02562.16 KXH59707.1 - 0.0063 16.0 0.0 0.0093 15.4 0.0 1.3 1 0 0 1 1 1 1 PhoH-like protein Sigma54_activ_2 PF14532.6 KXH59707.1 - 0.0069 16.5 0.0 0.016 15.4 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_23 PF13476.6 KXH59707.1 - 0.0073 16.8 0.0 0.017 15.6 0.0 1.6 2 0 0 2 2 1 1 AAA domain TsaE PF02367.17 KXH59707.1 - 0.01 15.8 0.0 0.014 15.4 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NB-ARC PF00931.22 KXH59707.1 - 0.016 14.4 0.1 0.033 13.4 0.0 1.5 2 0 0 2 2 2 0 NB-ARC domain Mg_chelatase PF01078.21 KXH59707.1 - 0.017 14.5 0.0 0.031 13.7 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Cytidylate_kin PF02224.18 KXH59707.1 - 0.019 14.7 0.0 0.03 14.1 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase AAA_28 PF13521.6 KXH59707.1 - 0.021 15.1 1.1 0.084 13.1 0.2 2.1 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KXH59707.1 - 0.023 14.4 0.0 0.028 14.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KXH59707.1 - 0.038 14.0 0.0 0.12 12.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 KXH59707.1 - 0.042 13.4 0.0 0.09 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KXH59707.1 - 0.056 13.2 0.0 0.089 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KXH59707.1 - 0.066 13.0 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sigma54_activat PF00158.26 KXH59707.1 - 0.069 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain dNK PF01712.19 KXH59707.1 - 0.075 12.9 0.1 1.6 8.5 0.0 2.3 1 1 0 2 2 2 0 Deoxynucleoside kinase PIF1 PF05970.14 KXH59707.1 - 0.081 12.1 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase ATPase PF06745.13 KXH59707.1 - 0.094 12.0 0.1 0.19 11.1 0.1 1.4 1 0 0 1 1 1 0 KaiC RuvB_N PF05496.12 KXH59707.1 - 0.1 12.4 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain ResIII PF04851.15 KXH59707.1 - 0.11 12.5 0.0 0.15 12.0 0.0 1.4 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit ATPase_2 PF01637.18 KXH59707.1 - 0.11 12.4 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_19 PF13245.6 KXH59707.1 - 0.12 12.7 0.0 0.26 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KXH59707.1 - 0.14 12.0 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_PrkA PF08298.11 KXH59707.1 - 0.2 10.6 0.0 0.29 10.0 0.0 1.2 1 0 0 1 1 1 0 PrkA AAA domain RsgA_GTPase PF03193.16 KXH59707.1 - 0.2 11.6 0.0 0.34 10.8 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase Aldedh PF00171.22 KXH59708.1 - 1.2e-141 472.5 0.3 1.5e-141 472.1 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KXH59708.1 - 0.0044 16.1 0.0 0.0072 15.4 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.11 KXH59708.1 - 0.012 15.0 0.0 4.7 6.6 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) Transferase PF02458.15 KXH59709.1 - 9.9e-07 27.7 0.0 1.3e-05 24.1 0.0 2.2 2 1 0 2 2 2 2 Transferase family tRNA-synt_2 PF00152.20 KXH59710.1 - 2.9e-72 243.4 0.0 4.7e-72 242.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.9 KXH59710.1 - 2.6e-14 52.9 0.0 3.7e-14 52.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2156) tRNA_anti-codon PF01336.25 KXH59710.1 - 2e-08 34.1 0.0 7e-08 32.3 0.0 2.0 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Rgp1 PF08737.10 KXH59710.1 - 0.095 11.9 3.1 0.34 10.0 0.0 2.1 2 0 0 2 2 2 0 Rgp1 Peptidase_S64 PF08192.11 KXH59710.1 - 0.31 9.5 5.7 0.32 9.4 4.0 1.7 2 0 0 2 2 2 0 Peptidase family S64 Abhydrolase_3 PF07859.13 KXH59711.1 - 1.4e-43 149.2 0.0 2.2e-43 148.6 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXH59711.1 - 1.3e-05 25.9 0.4 1.3e-05 25.9 0.4 1.4 2 0 0 2 2 2 1 Alpha/beta hydrolase family COesterase PF00135.28 KXH59711.1 - 0.0001 21.4 0.0 0.00046 19.2 0.0 1.8 2 0 0 2 2 2 1 Carboxylesterase family Abhydrolase_2 PF02230.16 KXH59711.1 - 0.0076 16.1 0.0 0.022 14.6 0.0 1.7 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Esterase PF00756.20 KXH59711.1 - 0.0093 15.6 0.0 3.3 7.3 0.0 2.4 2 0 0 2 2 2 2 Putative esterase Peptidase_S9 PF00326.21 KXH59711.1 - 0.017 14.6 0.0 0.081 12.4 0.0 2.1 1 1 0 1 1 1 0 Prolyl oligopeptidase family AXE1 PF05448.12 KXH59711.1 - 0.16 10.7 0.0 6.7 5.3 0.0 2.1 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) DUF829 PF05705.14 KXH59711.1 - 0.2 11.5 0.0 0.44 10.4 0.0 1.6 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF829) Methyltransf_23 PF13489.6 KXH59712.1 - 4.6e-24 85.1 0.0 1.2e-23 83.8 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH59712.1 - 2.4e-10 41.0 0.0 1e-09 39.0 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH59712.1 - 1.8e-09 37.5 0.0 4.9e-05 23.2 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 KXH59712.1 - 2.4e-07 31.3 0.0 1e-06 29.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH59712.1 - 6.2e-07 30.1 0.0 6.8e-06 26.7 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 KXH59712.1 - 0.014 15.0 0.0 0.024 14.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain CheR PF01739.18 KXH59712.1 - 0.022 14.2 0.0 0.04 13.4 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain FtsJ PF01728.19 KXH59712.1 - 0.12 12.5 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase PrmA PF06325.13 KXH59712.1 - 0.14 11.5 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Ank_2 PF12796.7 KXH59713.1 - 4.3e-13 49.7 0.0 6.1e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXH59713.1 - 1.5e-12 47.7 0.8 9.1e-07 29.3 0.1 3.1 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXH59713.1 - 1.4e-10 41.2 0.5 4.2e-10 39.7 0.2 1.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXH59713.1 - 1.2e-09 37.5 0.0 4.8e-06 26.5 0.1 2.9 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 KXH59713.1 - 1.4e-09 37.9 0.3 5.7e-07 29.7 0.9 2.4 2 0 0 2 2 2 2 Ankyrin repeat Sec7 PF01369.20 KXH59714.1 - 6.4e-28 97.7 0.2 1.4e-27 96.6 0.0 1.5 2 0 0 2 2 2 1 Sec7 domain PH_9 PF15410.6 KXH59714.1 - 8.2e-18 64.9 0.0 1.9e-17 63.8 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain Methyltransf_16 PF10294.9 KXH59797.1 - 9.5e-43 145.9 0.0 1.2e-42 145.6 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Cons_hypoth95 PF03602.15 KXH59797.1 - 0.027 14.1 0.0 0.039 13.6 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 MTS PF05175.14 KXH59797.1 - 0.049 13.2 0.0 0.078 12.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain He_PIG PF05345.12 KXH59798.1 - 1.3e-11 44.5 18.6 6.9e-05 23.0 0.8 5.8 5 1 1 6 6 6 3 Putative Ig domain Cadherin_C_2 PF16492.5 KXH59798.1 - 0.0011 19.7 0.0 0.013 16.2 0.0 2.6 2 0 0 2 2 2 1 Cadherin cytoplasmic C-terminal TMEM154 PF15102.6 KXH59798.1 - 0.0035 17.3 0.2 0.012 15.5 0.1 2.0 2 0 0 2 2 2 1 TMEM154 protein family Herpes_gE PF02480.16 KXH59798.1 - 0.029 13.1 0.0 0.049 12.4 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF5305 PF17231.2 KXH59798.1 - 0.033 13.6 0.6 0.15 11.4 0.1 2.3 3 0 0 3 3 3 0 Family of unknown function (DUF5305) DUF4448 PF14610.6 KXH59798.1 - 0.039 13.7 0.0 0.077 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) EphA2_TM PF14575.6 KXH59798.1 - 0.089 13.7 0.0 0.22 12.4 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain MGC-24 PF05283.11 KXH59798.1 - 1.1 9.7 3.3 1.6 9.2 0.1 2.6 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin PP2C PF00481.21 KXH59799.1 - 5.2e-85 285.2 0.0 5.2e-85 285.2 0.0 1.5 2 0 0 2 2 2 1 Protein phosphatase 2C PPR_2 PF13041.6 KXH59800.1 - 8.9e-06 25.8 2.3 0.11 12.7 0.1 3.0 2 1 0 2 2 2 2 PPR repeat family mRNA_stabil PF13929.6 KXH59800.1 - 0.00033 19.8 0.0 0.00055 19.0 0.0 1.3 1 0 0 1 1 1 1 mRNA stabilisation SLS PF14611.6 KXH59800.1 - 0.045 13.6 0.0 0.15 11.9 0.0 1.7 1 1 0 1 1 1 0 Mitochondrial inner-membrane-bound regulator PPR PF01535.20 KXH59800.1 - 4.1 7.9 4.7 12 6.4 0.6 2.7 2 0 0 2 2 2 0 PPR repeat DUF3755 PF12579.8 KXH59801.1 - 0.13 11.9 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3755) Peroxin-13_N PF04088.13 KXH59801.1 - 0.89 9.8 3.8 0.57 10.4 0.1 2.4 3 0 0 3 3 3 0 Peroxin 13, N-terminal region RAP1 PF07218.11 KXH59801.1 - 8.5 4.5 13.1 0.37 9.0 2.3 2.0 2 0 0 2 2 2 0 Rhoptry-associated protein 1 (RAP-1) Apolipoprotein PF01442.18 KXH59802.1 - 0.0016 18.4 1.3 0.002 18.0 1.3 1.1 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF1202 PF06717.11 KXH59802.1 - 0.096 12.1 3.4 0.12 11.8 3.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1202) PRP1_N PF06424.12 KXH59803.1 - 7.3e-52 175.7 9.2 1.7e-51 174.5 9.2 1.7 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.6 KXH59803.1 - 1.6e-28 96.9 35.9 0.0013 19.4 0.2 14.0 4 2 12 16 16 15 9 Tetratricopeptide repeat TPR_19 PF14559.6 KXH59803.1 - 2.4e-27 95.2 15.6 4.1e-07 30.4 0.4 10.1 5 3 4 10 10 10 7 Tetratricopeptide repeat TPR_2 PF07719.17 KXH59803.1 - 1.6e-14 52.7 10.9 0.12 12.5 0.0 10.7 11 1 1 12 12 10 2 Tetratricopeptide repeat TPR_16 PF13432.6 KXH59803.1 - 1.8e-14 54.1 18.0 1.1e-06 29.1 0.8 7.6 7 2 2 9 9 8 2 Tetratricopeptide repeat TPR_17 PF13431.6 KXH59803.1 - 1.2e-12 47.3 3.9 0.7 10.4 0.0 9.1 8 1 0 8 8 8 2 Tetratricopeptide repeat TPR_8 PF13181.6 KXH59803.1 - 1.2e-12 46.9 3.7 0.012 15.8 0.1 8.3 9 0 0 9 9 8 3 Tetratricopeptide repeat NARP1 PF12569.8 KXH59803.1 - 8.4e-09 34.9 9.9 0.23 10.3 0.0 6.0 4 1 2 6 6 6 3 NMDA receptor-regulated protein 1 TPR_15 PF13429.6 KXH59803.1 - 2.6e-08 33.4 23.1 0.00012 21.4 6.0 6.5 2 2 3 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 KXH59803.1 - 1.7e-07 30.7 0.3 0.1 12.5 0.0 5.5 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 KXH59803.1 - 8.9e-07 29.0 9.3 0.00073 19.6 0.0 6.4 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_21 PF09976.9 KXH59803.1 - 5.7e-05 22.9 17.3 0.006 16.3 1.0 5.1 3 2 2 5 5 5 2 Tetratricopeptide repeat-like domain Suf PF05843.14 KXH59803.1 - 5.9e-05 23.2 0.2 7.3 6.5 0.0 5.0 5 1 1 6 6 6 2 Suppressor of forked protein (Suf) ANAPC3 PF12895.7 KXH59803.1 - 0.00017 21.7 0.2 1.8 8.8 0.0 4.5 3 1 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 Wzy_C_2 PF11846.8 KXH59803.1 - 0.00021 21.3 1.4 1 9.2 0.1 4.2 3 1 1 4 4 4 1 Virulence factor membrane-bound polymerase, C-terminal TPR_11 PF13414.6 KXH59803.1 - 0.0012 18.5 10.5 4.9 6.9 0.0 6.2 7 0 0 7 7 7 1 TPR repeat TPR_6 PF13174.6 KXH59803.1 - 0.007 16.9 12.5 12 6.8 0.1 8.5 10 0 0 10 10 8 0 Tetratricopeptide repeat DUF3808 PF10300.9 KXH59803.1 - 0.019 13.7 2.4 6.3 5.4 0.0 4.2 4 1 2 6 6 6 0 Protein of unknown function (DUF3808) TPR_7 PF13176.6 KXH59803.1 - 0.029 14.4 1.5 7.5 6.8 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat ChAPs PF09295.10 KXH59803.1 - 0.66 8.9 5.5 4.6 6.1 0.3 3.2 2 1 1 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) RrnaAD PF00398.20 KXH59804.1 - 1.6e-52 178.2 0.0 9.7e-51 172.4 0.0 2.1 1 1 0 1 1 1 1 Ribosomal RNA adenine dimethylase PCMT PF01135.19 KXH59804.1 - 4.5e-05 23.3 0.0 7e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 KXH59804.1 - 7.4e-05 23.4 0.0 0.00015 22.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KXH59804.1 - 0.0013 18.1 0.0 0.002 17.5 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.12 KXH59804.1 - 0.0053 17.4 0.0 0.012 16.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXH59804.1 - 0.0095 15.8 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH59804.1 - 0.011 16.4 0.0 0.03 15.0 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_28 PF02636.17 KXH59804.1 - 0.016 14.9 0.0 0.11 12.1 0.0 2.1 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_4 PF02390.17 KXH59804.1 - 0.04 13.4 0.0 0.13 11.8 0.0 1.8 2 0 0 2 2 2 0 Putative methyltransferase Nop53 PF07767.11 KXH59804.1 - 0.063 12.7 3.2 0.093 12.1 3.2 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) AAA_lid_4 PF17864.1 KXH59804.1 - 0.11 12.3 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 RuvB AAA lid domain Ubie_methyltran PF01209.18 KXH59804.1 - 0.11 11.8 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Cwf_Cwc_15 PF04889.12 KXH59804.1 - 0.15 11.8 8.8 0.21 11.3 8.8 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Sigma70_ner PF04546.13 KXH59804.1 - 0.16 11.9 6.0 0.24 11.3 6.0 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Rhabdo_ncap PF00945.18 KXH59804.1 - 0.35 9.7 6.0 0.21 10.4 3.8 1.6 2 0 0 2 2 2 0 Rhabdovirus nucleocapsid protein CDC45 PF02724.14 KXH59804.1 - 0.86 7.8 4.4 1.1 7.4 4.4 1.1 1 0 0 1 1 1 0 CDC45-like protein SUV3_C PF12513.8 KXH59805.1 - 1 9.3 4.4 4.2 7.4 0.1 2.4 1 1 1 2 2 2 0 Mitochondrial degradasome RNA helicase subunit C terminal Vac7 PF12751.7 KXH59806.1 - 2.8e-144 481.3 13.5 3.6e-126 421.6 1.5 3.7 4 0 0 4 4 4 2 Vacuolar segregation subunit 7 DUF953 PF06110.11 KXH59807.1 - 3.9e-18 65.2 0.0 4.7e-18 64.9 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin PF00085.20 KXH59807.1 - 0.0078 16.2 0.1 0.014 15.3 0.1 1.5 1 1 0 1 1 1 1 Thioredoxin FapA PF03961.13 KXH59808.1 - 0.23 10.0 14.9 0.027 13.1 9.7 1.9 2 0 0 2 2 2 0 Flagellar Assembly Protein A Herpes_UL6 PF01763.16 KXH59808.1 - 0.27 9.7 5.6 0.53 8.7 5.6 1.4 1 0 0 1 1 1 0 Herpesvirus UL6 like DotU PF09850.9 KXH59808.1 - 1.8 8.2 5.4 38 3.9 5.6 2.4 1 1 1 2 2 2 0 Type VI secretion system protein DotU Fez1 PF06818.15 KXH59808.1 - 2.7 8.4 32.5 0.15 12.5 19.4 2.4 2 0 0 2 2 2 0 Fez1 Laminin_II PF06009.12 KXH59808.1 - 4.4 7.3 16.6 2.6 8.1 12.0 2.7 2 1 0 2 2 2 0 Laminin Domain II DUF4615 PF15393.6 KXH59808.1 - 4.5 7.8 12.5 0.37 11.4 6.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4615) ALMT PF11744.8 KXH59808.1 - 5.1 5.8 9.7 9.3 5.0 9.7 1.5 1 0 0 1 1 1 0 Aluminium activated malate transporter Golgin_A5 PF09787.9 KXH59808.1 - 7.5 5.9 36.6 0.15 11.5 20.7 2.2 2 0 0 2 2 2 0 Golgin subfamily A member 5 Ribosomal_L7Ae PF01248.26 KXH59809.1 - 1.5e-23 82.3 0.0 1.8e-23 82.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Ribosomal_L16 PF00252.18 KXH59810.1 - 2.3e-45 153.8 0.1 2.9e-45 153.5 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e FlxA PF14282.6 KXH59812.1 - 0.011 15.7 1.1 0.026 14.5 1.1 1.5 1 0 0 1 1 1 0 FlxA-like protein FUSC_2 PF13515.6 KXH59813.1 - 8.6e-26 90.5 9.5 8.6e-26 90.5 9.5 2.6 2 0 0 2 2 2 1 Fusaric acid resistance protein-like FUSC PF04632.12 KXH59813.1 - 4.7e-05 22.2 1.2 4.7e-05 22.2 1.2 2.6 2 0 0 2 2 2 1 Fusaric acid resistance protein family ArAE_2 PF10334.9 KXH59813.1 - 0.0064 16.4 0.1 0.022 14.6 0.0 2.0 2 0 0 2 2 2 1 Aromatic acid exporter family member 2 ALMT PF11744.8 KXH59813.1 - 0.65 8.8 20.6 22 3.7 0.0 4.4 4 1 0 4 4 4 0 Aluminium activated malate transporter PNTB_4TM PF12769.7 KXH59813.1 - 1.6 9.2 7.9 0.67 10.5 2.2 3.1 3 0 0 3 3 3 0 4TM region of pyridine nucleotide transhydrogenase, mitoch HAD_2 PF13419.6 KXH59815.1 - 6.9e-14 52.3 0.0 7e-13 49.0 0.0 2.1 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KXH59815.1 - 1.4e-11 45.1 0.0 2.4e-08 34.5 0.0 2.2 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KXH59815.1 - 6.3e-06 26.2 0.3 1.4e-05 25.0 0.3 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 KXH59815.1 - 1.7e-05 25.3 0.1 0.00014 22.3 0.1 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 KXH59815.1 - 0.001 18.8 0.1 0.8 9.3 0.0 2.3 2 0 0 2 2 2 2 Mitochondrial PGP phosphatase Acid_PPase PF12689.7 KXH59815.1 - 0.2 11.5 0.0 0.3 10.9 0.0 1.3 1 0 0 1 1 1 0 Acid Phosphatase Pkinase PF00069.25 KXH59816.1 - 7.2e-65 219.0 0.0 9.5e-65 218.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXH59816.1 - 5.7e-40 137.2 0.0 7.4e-40 136.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXH59816.1 - 0.00011 21.7 0.0 0.00022 20.6 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KXH59816.1 - 0.00016 20.6 0.0 0.00026 19.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 KXH59816.1 - 0.036 13.0 0.0 0.049 12.6 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 KXH59816.1 - 0.073 12.1 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 SH2_2 PF14633.6 KXH59817.1 - 1.1e-83 280.0 0.0 1.1e-83 280.0 0.0 2.0 2 0 0 2 2 2 1 SH2 domain HTH_44 PF14641.6 KXH59817.1 - 2.1e-39 134.5 1.0 7e-39 132.8 1.0 1.9 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 HHH_7 PF14635.6 KXH59817.1 - 1.5e-30 105.6 0.0 3.4e-30 104.5 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.6 KXH59817.1 - 3.5e-29 101.5 0.0 1.7e-28 99.3 0.0 2.3 2 0 0 2 2 2 1 Holliday-junction resolvase-like of SPT6 SPT6_acidic PF14632.6 KXH59817.1 - 6.2e-20 71.6 33.1 6.2e-20 71.6 33.1 7.6 4 1 4 8 8 8 1 Acidic N-terminal SPT6 HHH_9 PF17674.1 KXH59817.1 - 3.9e-06 27.7 6.0 2.2e-05 25.3 2.0 4.2 3 1 0 3 3 3 1 HHH domain SH2 PF00017.24 KXH59817.1 - 0.0002 21.4 0.0 0.00052 20.0 0.0 1.8 1 0 0 1 1 1 1 SH2 domain HHH_3 PF12836.7 KXH59817.1 - 0.00036 20.7 0.0 0.001 19.3 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif Glyco_hydro_16 PF00722.21 KXH59818.1 - 0.086 12.3 0.1 0.086 12.3 0.1 3.1 2 1 0 2 2 2 0 Glycosyl hydrolases family 16 RRP7 PF12923.7 KXH59819.1 - 6e-29 100.6 14.6 6e-29 100.6 14.6 1.8 2 0 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain MOSC PF03473.17 KXH59819.1 - 7e-19 68.1 0.0 4.5e-18 65.5 0.0 2.3 1 1 0 1 1 1 1 MOSC domain RRM_Rrp7 PF17799.1 KXH59819.1 - 2.1e-16 60.1 0.0 4.3e-16 59.1 0.0 1.5 1 0 0 1 1 1 1 Rrp7 RRM-like N-terminal domain Fer2 PF00111.27 KXH59819.1 - 1.6e-10 40.8 1.0 4e-10 39.5 1.0 1.6 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain 3-alpha PF03475.14 KXH59819.1 - 7.4e-05 22.5 0.1 0.00025 20.8 0.1 2.0 1 0 0 1 1 1 1 3-alpha domain NAD_binding_1 PF00175.21 KXH59819.1 - 0.00028 21.5 2.5 0.0023 18.6 0.0 3.3 3 1 0 3 3 3 1 Oxidoreductase NAD-binding domain ANF_receptor PF01094.28 KXH59819.1 - 0.11 11.6 0.7 1.1 8.3 0.1 2.3 2 1 0 2 2 2 0 Receptor family ligand binding region Usp PF00582.26 KXH59819.1 - 0.75 10.3 4.5 1.3 9.5 0.4 2.5 2 0 0 2 2 2 0 Universal stress protein family F-box PF00646.33 KXH59820.1 - 1.7e-08 34.1 0.1 4.1e-08 32.9 0.1 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KXH59820.1 - 1.1e-05 25.2 0.0 2.5e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 KXH59820.1 - 0.024 14.5 0.0 0.044 13.7 0.0 1.4 1 0 0 1 1 1 0 F-box BAR PF03114.18 KXH59821.1 - 8.1e-70 235.2 8.3 1.1e-69 234.8 8.3 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 KXH59821.1 - 1.1e-15 57.0 0.1 2.4e-15 55.9 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KXH59821.1 - 3e-14 52.6 0.0 5.2e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KXH59821.1 - 1.1e-10 41.0 0.3 6.1e-10 38.6 0.0 2.3 3 0 0 3 3 3 1 Variant SH3 domain TMPIT PF07851.13 KXH59821.1 - 0.038 13.2 5.4 1.7 7.8 0.0 2.2 1 1 1 2 2 2 0 TMPIT-like protein Aminotran_5 PF00266.19 KXH59822.1 - 3.7e-90 302.5 0.0 4.6e-90 302.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KXH59822.1 - 6.4e-05 22.4 0.0 0.00032 20.1 0.0 1.9 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 KXH59822.1 - 9.4e-05 21.8 0.0 0.00015 21.2 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Pyridoxal_deC PF00282.19 KXH59822.1 - 0.011 14.5 0.0 0.018 13.8 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain Cys_Met_Meta_PP PF01053.20 KXH59822.1 - 0.13 10.7 0.0 0.2 10.1 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme DUF3942 PF13078.6 KXH59822.1 - 0.18 12.1 0.0 0.39 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3942) CsbD PF05532.12 KXH59823.1 - 2.2e-15 56.3 23.2 2.1e-11 43.5 4.8 3.6 2 1 2 4 4 4 2 CsbD-like UPF0444 PF15475.6 KXH59823.1 - 1.9 8.8 6.5 1.3 9.3 0.4 2.7 3 0 0 3 3 3 0 Transmembrane protein C12orf23, UPF0444 CMD PF02627.20 KXH59826.1 - 6.3e-09 35.8 0.0 7.8e-08 32.3 0.0 2.1 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family SPT16 PF08644.11 KXH59827.1 - 2.1e-54 183.8 0.1 2.1e-54 183.8 0.1 2.3 2 0 0 2 2 2 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.6 KXH59827.1 - 3.3e-53 179.8 0.9 1.4e-52 177.7 0.9 2.2 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.24 KXH59827.1 - 7.6e-26 91.1 0.0 1.6e-25 90.1 0.0 1.5 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 KXH59827.1 - 4.4e-16 59.1 1.0 1.7e-15 57.2 0.2 2.5 2 0 0 2 2 2 1 Histone chaperone Rttp106-like CDC50 PF03381.15 KXH59828.1 - 1.5e-104 349.5 0.2 1.8e-104 349.2 0.2 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Asp4 PF16996.5 KXH59828.1 - 0.086 12.6 1.2 0.25 11.1 1.2 1.8 1 0 0 1 1 1 0 Accessory secretory protein Sec Asp4 cNMP_binding PF00027.29 KXH59829.1 - 2.3e-40 136.6 0.0 5.2e-21 74.5 0.0 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain BCAS2 PF05700.11 KXH59830.1 - 9.3e-57 192.1 1.0 1.1e-56 191.9 1.0 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) CFEM PF05730.11 KXH59831.1 - 4.9e-13 49.0 12.6 8.5e-13 48.2 12.6 1.4 1 0 0 1 1 1 1 CFEM domain Antimicrobial_4 PF08024.11 KXH59831.1 - 9.4 6.4 6.0 0.79 9.9 0.3 2.1 2 0 0 2 2 2 0 Ant antimicrobial peptide HABP4_PAI-RBP1 PF04774.15 KXH59833.1 - 0.21 12.4 3.6 0.41 11.5 3.6 1.6 1 1 0 1 1 1 0 Hyaluronan / mRNA binding family Pkr1 PF08636.10 KXH59860.1 - 5.5e-30 103.3 6.6 7.1e-30 103.0 6.6 1.1 1 0 0 1 1 1 1 ER protein Pkr1 TraT PF05818.12 KXH59860.1 - 1.8 8.2 8.9 3.3 7.3 8.9 1.4 1 1 0 1 1 1 0 Enterobacterial TraT complement resistance protein MFS_2 PF13347.6 KXH59861.1 - 9e-13 47.6 11.6 9e-13 47.6 11.6 2.8 3 0 0 3 3 3 1 MFS/sugar transport protein PUCC PF03209.15 KXH59861.1 - 2.3e-05 23.6 3.7 2.3e-05 23.6 3.7 1.5 2 0 0 2 2 2 1 PUCC protein MFS_1_like PF12832.7 KXH59861.1 - 9.3e-05 21.4 5.0 9.3e-05 21.4 5.0 1.8 2 0 0 2 2 2 1 MFS_1 like family DUF2070 PF09843.9 KXH59861.1 - 0.32 9.2 4.2 8.5 4.5 2.7 3.0 2 2 0 2 2 2 0 Predicted membrane protein (DUF2070) HisG PF01634.18 KXH59862.1 - 1.4e-55 187.7 0.1 2.1e-55 187.0 0.1 1.3 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.11 KXH59862.1 - 3.6e-28 97.5 0.1 1.5e-27 95.5 0.1 2.0 2 0 0 2 2 2 1 HisG, C-terminal domain Ferric_reduct PF01794.19 KXH59863.1 - 0.0037 17.4 0.4 0.0064 16.6 0.4 1.3 1 0 0 1 1 1 1 Ferric reductase like transmembrane component Peptidase_C14 PF00656.22 KXH59865.1 - 2.5e-60 204.5 0.0 3.1e-60 204.2 0.0 1.1 1 0 0 1 1 1 1 Caspase domain EF-hand_1 PF00036.32 KXH59866.1 - 8.3e-30 100.1 0.3 9.6e-08 31.1 0.0 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 KXH59866.1 - 4.5e-25 87.2 0.6 9.6e-11 41.4 0.0 3.1 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_7 PF13499.6 KXH59866.1 - 2.2e-23 82.5 0.0 8.2e-13 48.6 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KXH59866.1 - 7.5e-21 72.2 0.0 6.3e-07 28.8 0.0 4.4 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 KXH59866.1 - 7.7e-19 66.3 1.5 2.7e-06 26.6 0.0 4.4 4 0 0 4 4 4 3 EF hand EF-hand_9 PF14658.6 KXH59866.1 - 7.9e-11 42.1 0.0 7.2e-05 23.0 0.0 2.3 2 1 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 KXH59866.1 - 7.7e-06 25.8 0.5 0.11 12.5 0.0 2.8 2 1 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 KXH59866.1 - 0.00013 22.3 0.0 0.0084 16.4 0.0 2.1 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region SurA_N_3 PF13624.6 KXH59866.1 - 0.0019 18.0 0.1 1.4 8.7 0.0 2.2 1 1 0 2 2 2 2 SurA N-terminal domain EF-hand_11 PF08976.11 KXH59866.1 - 0.003 18.4 0.0 0.16 12.8 0.0 2.2 1 1 1 2 2 2 1 EF-hand domain DUF5580 PF17743.1 KXH59866.1 - 0.0052 15.4 0.0 0.0058 15.2 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5580) Dockerin_1 PF00404.18 KXH59866.1 - 0.008 16.4 0.1 2.1 8.6 0.1 2.4 2 1 0 2 2 2 1 Dockerin type I domain SurA_N_2 PF13623.6 KXH59866.1 - 0.031 14.1 0.2 2.8 7.8 0.0 2.3 2 0 0 2 2 2 0 SurA N-terminal domain UPF0154 PF03672.13 KXH59866.1 - 0.089 12.8 0.0 18 5.4 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) CYSTM PF12734.7 KXH59867.1 - 9.7e-08 32.2 20.4 9.7e-08 32.2 20.4 4.3 1 1 3 4 4 4 1 Cysteine-rich TM module stress tolerance G_path_suppress PF15991.5 KXH59867.1 - 9.7 6.2 5.9 10 6.1 5.9 1.0 1 0 0 1 1 1 0 G-protein pathway suppressor WW PF00397.26 KXH59868.1 - 1.2e-09 38.1 3.7 1.2e-09 38.1 3.7 2.2 2 0 0 2 2 2 1 WW domain KinB_sensor PF16767.5 KXH59868.1 - 0.19 12.2 1.9 0.34 11.4 1.9 1.4 1 0 0 1 1 1 0 Sensor domain of alginate biosynthesis sensor protein KinB TPR_2 PF07719.17 KXH59868.1 - 0.63 10.3 7.3 7.8 6.9 0.7 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF4404 PF14357.6 KXH59868.1 - 0.92 10.2 3.2 1.8 9.2 3.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) TPR_10 PF13374.6 KXH59868.1 - 1.9 8.5 7.9 2.7 8.0 1.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Myb_DNA-bind_6 PF13921.6 KXH59869.1 - 0.00053 20.2 0.1 0.00093 19.4 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain CVNH PF08881.10 KXH59932.1 - 1.3e-24 86.8 1.0 1.7e-24 86.4 1.0 1.1 1 0 0 1 1 1 1 CVNH domain Ribosomal_L50 PF10501.9 KXH59934.1 - 2.3e-16 59.9 0.4 4.2e-16 59.0 0.0 1.6 2 0 0 2 2 2 1 Ribosomal subunit 39S RIB43A PF05914.12 KXH59934.1 - 0.014 14.2 6.4 0.021 13.6 6.4 1.2 1 0 0 1 1 1 0 RIB43A SAP PF02037.27 KXH59934.1 - 0.02 14.6 0.0 0.045 13.5 0.0 1.6 1 0 0 1 1 1 0 SAP domain DUF3446 PF11928.8 KXH59935.1 - 0.25 11.7 8.0 12 6.3 5.3 2.3 2 0 0 2 2 2 0 Early growth response N-terminal domain DAHP_synth_1 PF00793.20 KXH59936.1 - 6.6e-104 346.6 0.1 8.2e-104 346.3 0.1 1.0 1 0 0 1 1 1 1 DAHP synthetase I family COX14 PF14880.6 KXH59938.1 - 3e-21 75.0 1.1 5.2e-21 74.3 0.3 1.9 2 0 0 2 2 2 1 Cytochrome oxidase c assembly PRP4 PF08799.11 KXH59938.1 - 0.067 12.8 0.4 0.14 11.8 0.4 1.5 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like Ribosomal_L13e PF01294.18 KXH59940.1 - 2.6e-76 255.5 2.0 3.5e-76 255.1 2.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L13e Sugar_tr PF00083.24 KXH59943.1 - 1.3e-81 274.8 22.7 1.6e-81 274.5 22.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH59943.1 - 2e-31 109.2 53.8 3e-25 88.9 30.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KXH59943.1 - 0.00013 20.6 1.7 0.00013 20.6 1.7 2.1 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Aldo_ket_red PF00248.21 KXH59944.1 - 8.9e-70 235.2 0.1 1.1e-69 234.9 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family FMO-like PF00743.19 KXH59945.1 - 1.1e-63 215.5 0.0 2.3e-63 214.4 0.0 1.5 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KXH59945.1 - 7.3e-14 51.7 0.0 4.5e-11 42.6 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXH59945.1 - 6.9e-10 38.6 0.0 1.6e-08 34.2 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXH59945.1 - 2.4e-09 37.4 0.1 3.1e-06 27.3 0.0 3.9 3 1 0 3 3 3 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 KXH59945.1 - 1e-08 34.7 0.6 6.4e-07 28.8 0.1 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KXH59945.1 - 5e-08 32.9 0.1 0.046 13.3 0.0 3.4 2 1 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXH59945.1 - 1.9e-07 31.2 0.0 6.1e-07 29.6 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KXH59945.1 - 0.00019 20.9 0.1 0.2 10.9 0.0 3.9 5 0 0 5 5 5 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 KXH59945.1 - 0.0014 19.1 0.0 0.072 13.7 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KXH59945.1 - 0.0018 17.6 0.1 0.03 13.6 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain Shikimate_DH PF01488.20 KXH59945.1 - 0.0062 16.6 0.0 3.9 7.6 0.0 2.6 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.17 KXH59945.1 - 0.03 13.5 0.0 0.054 12.7 0.0 1.4 1 0 0 1 1 1 0 Thi4 family IlvN PF07991.12 KXH59945.1 - 0.099 12.2 0.0 0.33 10.5 0.0 1.8 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain DUF1593 PF07632.11 KXH59946.1 - 5.5e-95 317.7 0.0 7.1e-95 317.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1593) REJ PF02010.15 KXH59946.1 - 0.054 12.3 0.0 0.078 11.8 0.0 1.2 1 0 0 1 1 1 0 REJ domain Sugar_tr PF00083.24 KXH59947.1 - 4.5e-67 226.9 19.2 5e-67 226.7 19.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH59947.1 - 3.9e-18 65.5 23.8 3.9e-18 65.5 23.8 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 KXH59947.1 - 0.0015 17.5 6.1 0.34 9.7 0.4 3.0 1 1 1 3 3 3 3 MFS_1 like family MFS_1 PF07690.16 KXH59948.1 - 4.1e-39 134.5 37.9 4.8e-39 134.3 37.9 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH59948.1 - 4.9e-14 52.1 9.8 4.9e-14 52.1 9.8 2.2 3 0 0 3 3 3 1 Sugar (and other) transporter Fungal_trans PF04082.18 KXH59949.1 - 3.7e-13 49.1 0.1 6.2e-13 48.4 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH59949.1 - 3.7e-08 33.4 10.3 6.4e-08 32.6 10.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.22 KXH59952.1 - 8.1e-52 176.5 0.0 1.2e-51 176.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Tox-HDC PF15656.6 KXH59952.1 - 0.064 13.4 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Toxin with a H, D/N and C signature Exo_endo_phos PF03372.23 KXH59954.1 - 8.8e-08 31.9 1.3 1.2e-07 31.5 1.3 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Methyltransf_23 PF13489.6 KXH59955.1 - 2.1e-18 66.7 0.0 4.7e-18 65.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH59955.1 - 2e-10 41.2 0.0 6e-10 39.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH59955.1 - 2.3e-09 37.8 0.0 4.5e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH59955.1 - 1.3e-06 28.3 0.0 0.056 13.2 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 KXH59955.1 - 7.2e-06 26.7 0.0 8.2e-05 23.3 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXH59955.1 - 0.014 14.9 0.0 0.056 13.0 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_2 PF00891.18 KXH59955.1 - 0.021 14.1 0.0 0.038 13.3 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_4 PF02390.17 KXH59955.1 - 0.03 13.8 0.0 0.089 12.3 0.0 1.7 2 0 0 2 2 2 0 Putative methyltransferase Ubie_methyltran PF01209.18 KXH59955.1 - 0.03 13.6 0.0 0.32 10.3 0.0 2.3 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family PrmA PF06325.13 KXH59955.1 - 0.05 13.0 0.0 0.081 12.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_2 PF00891.18 KXH59956.1 - 1.2e-13 50.8 0.0 3e-13 49.6 0.0 1.6 1 1 0 1 1 1 1 O-methyltransferase domain DUF4632 PF15451.6 KXH59957.1 - 0.097 12.8 2.1 8.5 6.5 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4632) Pneumo_att_G PF05539.11 KXH59957.1 - 4.3 6.8 8.8 5.8 6.4 8.8 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G SET PF00856.28 KXH59962.1 - 4.8e-07 30.3 0.0 1.4e-06 28.8 0.0 1.7 1 1 0 1 1 1 1 SET domain MFS_1 PF07690.16 KXH59992.1 - 4.5e-18 65.3 38.2 2.6e-15 56.2 14.8 2.9 2 2 0 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH59992.1 - 2.6e-05 23.3 6.3 6.9e-05 21.9 5.9 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter Ku PF02735.16 KXH59994.1 - 3.2e-44 151.1 0.0 7.3e-44 149.9 0.0 1.6 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 KXH59994.1 - 4.5e-32 111.6 0.0 6.3e-32 111.1 0.0 1.2 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 KXH59994.1 - 9.5e-29 100.0 1.5 3.4e-28 98.2 1.5 2.0 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm SAP PF02037.27 KXH59994.1 - 3.7e-10 39.3 0.3 3.9e-09 36.0 0.2 2.3 2 0 0 2 2 2 1 SAP domain Ferrochelatase PF00762.19 KXH59995.1 - 1.8e-97 326.2 0.0 2.2e-97 326.0 0.0 1.1 1 0 0 1 1 1 1 Ferrochelatase Cytomega_UL20A PF05984.12 KXH59995.1 - 0.13 12.6 0.1 0.29 11.4 0.1 1.5 1 0 0 1 1 1 0 Cytomegalovirus UL20A protein HIT PF01230.23 KXH59996.1 - 1.6e-21 76.8 0.0 2.9e-21 76.0 0.0 1.4 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 KXH59996.1 - 9.2e-06 26.1 0.0 1.9e-05 25.1 0.0 1.5 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding AAA PF00004.29 KXH59997.1 - 4e-11 43.5 0.0 8.3e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KXH59997.1 - 1.5e-06 28.5 0.0 4.3e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KXH59997.1 - 1.5e-05 25.0 0.0 2.9e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KXH59997.1 - 5.2e-05 23.1 0.0 0.0001 22.1 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Rad17 PF03215.15 KXH59997.1 - 5.2e-05 23.3 0.0 0.00022 21.2 0.0 2.0 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_33 PF13671.6 KXH59997.1 - 0.0016 18.6 0.1 0.0051 17.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KXH59997.1 - 0.0018 18.0 0.1 0.0042 16.8 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 KXH59997.1 - 0.0025 17.9 0.0 0.0047 17.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KXH59997.1 - 0.0025 18.2 0.0 0.0092 16.4 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 KXH59997.1 - 0.017 15.6 0.0 0.04 14.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KXH59997.1 - 0.022 13.9 0.0 0.038 13.2 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain NTPase_1 PF03266.15 KXH59997.1 - 0.028 14.3 0.3 0.095 12.6 0.1 1.9 1 1 1 2 2 2 0 NTPase RsgA_GTPase PF03193.16 KXH59997.1 - 0.042 13.7 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase AAA_19 PF13245.6 KXH59997.1 - 0.069 13.5 0.5 0.34 11.3 0.5 2.1 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KXH59997.1 - 0.071 12.6 0.1 0.6 9.6 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region Mg_chelatase PF01078.21 KXH59997.1 - 0.084 12.2 0.0 1.5 8.1 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 KXH59997.1 - 0.095 12.4 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.10 KXH59997.1 - 0.098 12.1 0.1 0.2 11.1 0.1 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 ABC_tran PF00005.27 KXH59997.1 - 0.1 13.1 0.1 0.31 11.6 0.1 1.8 1 0 0 1 1 1 0 ABC transporter TsaE PF02367.17 KXH59997.1 - 0.11 12.5 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE GMC_oxred_N PF00732.19 KXH59998.1 - 1.8e-68 231.1 0.0 9.7e-63 212.3 0.0 2.1 2 0 0 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.13 KXH59998.1 - 1.3e-12 48.5 0.0 2.9e-12 47.3 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 KXH59998.1 - 0.005 16.5 0.1 0.089 12.4 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXH59998.1 - 0.0079 16.4 0.0 0.027 14.7 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KXH59998.1 - 0.025 13.6 0.0 1.4 7.9 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain Radical_SAM PF04055.21 KXH59999.1 - 4.8e-07 30.3 0.0 7.8e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 KXH59999.1 - 3.4e-05 24.1 0.0 7e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 KXH59999.1 - 0.011 15.9 0.0 0.03 14.4 0.0 1.8 1 0 0 1 1 1 0 4Fe-4S single cluster domain DUF1681 PF07933.14 KXH60001.1 - 2.7e-58 195.9 0.0 4.4e-58 195.2 0.0 1.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1681) FctA PF12892.7 KXH60001.1 - 0.1 13.4 0.0 7.6 7.4 0.0 2.6 3 0 0 3 3 3 0 Spy0128-like isopeptide containing domain IF-2B PF01008.17 KXH60002.1 - 2.8e-43 148.2 0.0 3.8e-43 147.7 0.0 1.2 1 0 0 1 1 1 1 Initiation factor 2 subunit family DeoRC PF00455.22 KXH60002.1 - 0.047 13.6 0.0 0.87 9.5 0.0 2.3 2 0 0 2 2 2 0 DeoR C terminal sensor domain Methyltransf_33 PF10017.9 KXH60003.1 - 1.8e-83 280.2 0.0 3e-83 279.5 0.0 1.3 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.16 KXH60003.1 - 7.1e-16 58.6 1.9 1.3e-09 38.0 0.1 2.9 2 1 0 2 2 2 2 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.7 KXH60003.1 - 0.0093 16.5 4.8 0.011 16.2 2.1 2.6 2 1 0 2 2 2 1 DinB superfamily Peptidase_S28 PF05577.12 KXH60004.1 - 1.2e-49 169.4 1.6 5.5e-49 167.1 1.6 1.8 1 1 0 1 1 1 1 Serine carboxypeptidase S28 DUF2920 PF11144.8 KXH60004.1 - 0.2 10.8 0.1 0.32 10.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) Fungal_trans PF04082.18 KXH60005.1 - 1.5e-16 60.3 0.0 2.9e-16 59.3 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH60005.1 - 1.1e-07 31.8 7.7 2.1e-07 31.0 7.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Clr5 PF14420.6 KXH60006.1 - 2.6e-08 34.0 0.1 5.2e-08 33.0 0.1 1.6 1 0 0 1 1 1 1 Clr5 domain DUF1774 PF08611.10 KXH60007.1 - 9e-38 128.5 1.4 9e-38 128.5 1.4 2.8 3 1 1 4 4 4 1 Fungal protein of unknown function (DUF1774) ACPS PF01648.20 KXH60008.1 - 3e-08 33.8 1.0 7.9e-08 32.4 1.0 1.9 1 1 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily 4PPT_N PF17837.1 KXH60008.1 - 9.6e-05 22.4 0.3 0.52 10.5 0.1 2.5 2 0 0 2 2 2 2 4'-phosphopantetheinyl transferase N-terminal domain AAA_6 PF12774.7 KXH60009.1 - 1.5e-126 421.8 0.0 8.1e-126 419.4 0.0 2.4 2 0 0 2 2 1 1 Hydrolytic ATP binding site of dynein motor region DHC_N1 PF08385.12 KXH60009.1 - 2e-117 393.2 7.7 2e-117 393.2 7.7 4.9 4 1 0 4 4 4 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 KXH60009.1 - 4.6e-117 391.5 8.6 4.6e-117 391.5 8.6 6.1 5 2 0 5 5 5 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 KXH60009.1 - 6.2e-73 244.6 1.4 6.2e-73 244.6 1.4 3.1 3 0 0 3 3 2 1 ATP-binding dynein motor region AAA_8 PF12780.7 KXH60009.1 - 2.1e-65 220.7 0.0 6.8e-65 219.0 0.0 2.0 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_7 PF12775.7 KXH60009.1 - 5.3e-43 146.6 0.0 2.7e-36 124.8 0.0 4.9 5 0 0 5 5 5 2 P-loop containing dynein motor region MT PF12777.7 KXH60009.1 - 1.6e-36 126.1 6.7 1.6e-36 126.1 6.7 1.9 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.14 KXH60009.1 - 3.9e-33 114.4 0.1 6.8e-12 45.6 0.0 6.3 5 1 0 5 5 5 4 AAA domain (dynein-related subfamily) Dynein_heavy PF03028.15 KXH60009.1 - 4.3e-29 101.0 0.0 4.7e-27 94.4 0.0 3.4 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain AAA_lid_11 PF18198.1 KXH60009.1 - 1.7e-28 99.5 0.0 4.5e-28 98.1 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_AAA_lid PF17852.1 KXH60009.1 - 1.5e-15 57.5 0.3 1.9e-14 53.9 0.0 3.0 3 0 0 3 3 2 1 Dynein heavy chain AAA lid domain AAA_22 PF13401.6 KXH60009.1 - 4.3e-15 56.2 0.9 0.0097 16.2 0.0 6.2 4 1 0 4 4 4 3 AAA domain AAA PF00004.29 KXH60009.1 - 7e-14 52.4 0.1 0.002 18.5 0.0 5.3 5 0 0 5 5 5 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KXH60009.1 - 9.7e-11 42.3 3.8 1.8 8.9 0.0 7.9 7 0 0 7 7 6 2 AAA ATPase domain AAA_33 PF13671.6 KXH60009.1 - 6.5e-09 36.1 1.1 0.46 10.6 0.1 5.1 4 0 0 4 4 4 3 AAA domain AAA_18 PF13238.6 KXH60009.1 - 2.1e-08 34.7 0.5 0.1 13.2 0.0 5.3 4 0 0 4 4 4 2 AAA domain T2SSE PF00437.20 KXH60009.1 - 1.9e-05 23.9 0.0 0.012 14.6 0.0 3.1 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_29 PF13555.6 KXH60009.1 - 4.1e-05 23.2 0.1 2.3 8.0 0.0 3.7 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_lid_1 PF17857.1 KXH60009.1 - 9.5e-05 22.6 0.4 0.0014 18.8 0.0 3.1 3 0 0 3 3 2 1 AAA+ lid domain Mg_chelatase PF01078.21 KXH60009.1 - 0.00031 20.2 1.0 0.68 9.3 0.0 3.8 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_30 PF13604.6 KXH60009.1 - 0.0013 18.5 0.6 39 3.9 0.0 5.0 4 0 0 4 4 4 0 AAA domain IstB_IS21 PF01695.17 KXH60009.1 - 0.0015 18.3 0.6 0.65 9.7 0.0 4.3 4 0 0 4 4 4 1 IstB-like ATP binding protein BRE1 PF08647.11 KXH60009.1 - 0.0038 17.3 2.6 0.0038 17.3 2.6 4.7 4 0 0 4 4 2 1 BRE1 E3 ubiquitin ligase AAA_19 PF13245.6 KXH60009.1 - 0.0041 17.5 4.0 0.28 11.5 0.0 4.5 5 0 0 5 5 4 1 AAA domain AAA_25 PF13481.6 KXH60009.1 - 0.0074 15.9 3.6 0.24 10.9 0.0 3.6 4 0 0 4 4 3 1 AAA domain RNA_helicase PF00910.22 KXH60009.1 - 0.0085 16.5 0.1 28 5.1 0.0 4.6 4 0 0 4 4 4 0 RNA helicase FtsK_SpoIIIE PF01580.18 KXH60009.1 - 0.016 14.6 2.7 2.4 7.4 0.0 4.3 4 0 0 4 4 4 0 FtsK/SpoIIIE family ABC_tran PF00005.27 KXH60009.1 - 0.026 15.0 5.6 6.2 7.3 0.0 5.0 5 0 0 5 5 3 0 ABC transporter Rad17 PF03215.15 KXH60009.1 - 0.05 13.5 0.1 6.8 6.6 0.0 3.6 4 0 0 4 4 2 0 Rad17 P-loop domain AAA_24 PF13479.6 KXH60009.1 - 0.063 13.0 5.8 11 5.7 0.0 4.8 5 0 0 5 5 5 0 AAA domain DUF4482 PF14818.6 KXH60009.1 - 0.069 14.0 8.2 39 5.1 8.2 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4482) PduV-EutP PF10662.9 KXH60009.1 - 1.1 9.0 3.9 11 5.7 0.1 3.9 4 0 0 4 4 4 0 Ethanolamine utilisation - propanediol utilisation ALMT PF11744.8 KXH60009.1 - 1.3 7.7 5.9 5.7 5.7 5.9 2.1 1 0 0 1 1 1 0 Aluminium activated malate transporter MbeB_N PF04837.12 KXH60009.1 - 1.8 9.0 6.1 2.9 8.3 0.1 4.0 3 0 0 3 3 2 0 MbeB-like, N-term conserved region Hemerythrin PF01814.23 KXH60009.1 - 7.1 7.3 6.3 3.9 8.1 0.0 4.0 5 0 0 5 5 1 0 Hemerythrin HHE cation binding domain NACHT PF05729.12 KXH60009.1 - 8.5 6.3 7.0 32 4.4 0.0 4.3 4 0 0 4 4 3 0 NACHT domain FAR1 PF03101.15 KXH60010.1 - 0.0025 18.4 0.0 0.0057 17.3 0.0 1.5 1 0 0 1 1 1 1 FAR1 DNA-binding domain Phosphodiest PF01663.22 KXH60010.1 - 0.0051 16.4 0.0 0.015 14.9 0.0 1.7 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase FRB_dom PF08771.11 KXH60010.1 - 0.09 13.2 0.3 0.87 10.0 0.1 2.3 2 0 0 2 2 2 0 FKBP12-rapamycin binding domain Golgin_A5 PF09787.9 KXH60010.1 - 4.4 6.7 11.8 0.13 11.7 1.8 2.1 2 0 0 2 2 2 0 Golgin subfamily A member 5 Chromo PF00385.24 KXH60018.1 - 1.2e-05 25.1 0.0 3.7e-05 23.6 0.0 1.8 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain DUF2722 PF10846.8 KXH60019.1 - 0.21 10.5 1.3 0.27 10.1 0.1 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2722) Pkinase PF00069.25 KXH60025.1 - 3.7e-53 180.6 0.0 5.2e-53 180.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXH60025.1 - 1.9e-20 73.2 0.0 3.6e-20 72.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXH60025.1 - 0.057 13.3 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Vmethyltransf_C PF08456.10 KXH60025.1 - 0.062 12.9 0.3 0.11 12.1 0.3 1.3 1 0 0 1 1 1 0 Viral methyltransferase C-terminal RIO1 PF01163.22 KXH60025.1 - 0.26 10.8 0.6 0.52 9.9 0.1 1.8 2 0 0 2 2 2 0 RIO1 family Choline_kinase PF01633.20 KXH60025.1 - 0.79 9.3 4.1 0.17 11.4 0.5 1.7 2 0 0 2 2 2 0 Choline/ethanolamine kinase Choline_transpo PF04515.12 KXH60030.1 - 1.2e-28 100.3 21.9 1.2e-28 100.3 21.9 2.3 2 1 0 2 2 2 1 Plasma-membrane choline transporter WW PF00397.26 KXH60031.1 - 1.2e-11 44.4 4.4 2e-11 43.7 4.4 1.4 1 0 0 1 1 1 1 WW domain Egh16-like PF11327.8 KXH60047.1 - 5.6e-67 225.7 12.8 1.9e-66 224.0 12.8 1.7 1 1 0 1 1 1 1 Egh16-like virulence factor PI-PLC-X PF00388.19 KXH60048.1 - 0.065 12.8 0.0 0.098 12.2 0.0 1.2 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain CorA PF01544.18 KXH60049.1 - 0.056 12.8 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Ribosomal_S14 PF00253.21 KXH60049.1 - 0.34 10.7 1.5 0.55 10.0 0.1 2.1 2 0 0 2 2 2 0 Ribosomal protein S14p/S29e MRC1 PF09444.10 KXH60050.1 - 4e-42 144.2 22.3 4e-42 144.2 22.3 9.3 8 2 1 10 10 10 1 MRC1-like domain Ldi PF18566.1 KXH60051.1 - 2.4e-134 447.8 0.0 2.9e-134 447.6 0.0 1.1 1 0 0 1 1 1 1 Linalool dehydratase/isomerase HepII_C PF18675.1 KXH60051.1 - 0.032 14.3 0.0 0.093 12.8 0.0 1.7 2 0 0 2 2 2 0 Heparinase II C-terminal domain Vps62 PF06101.11 KXH60052.1 - 2.2e-11 42.8 0.5 4.5e-11 41.7 0.5 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 62 TFIIIC_sub6 PF10419.9 KXH60053.1 - 4.4e-27 93.8 0.0 7.2e-27 93.1 0.0 1.3 1 0 0 1 1 1 1 TFIIIC subunit triple barrel domain His_biosynth PF00977.21 KXH60054.1 - 3.4e-48 164.1 0.7 1.2e-47 162.3 0.7 1.9 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.28 KXH60054.1 - 3.1e-17 63.0 0.0 4.8e-17 62.3 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.19 KXH60054.1 - 1.9e-08 34.4 0.0 1.1e-07 31.9 0.0 2.0 1 1 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 KXH60054.1 - 1.3e-05 24.9 0.0 2.8e-05 23.8 0.0 1.6 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Dus PF01207.17 KXH60054.1 - 0.016 14.3 0.0 0.036 13.2 0.0 1.5 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) TMP-TENI PF02581.17 KXH60054.1 - 0.041 13.2 0.2 12 5.2 0.0 3.0 3 0 0 3 3 3 0 Thiamine monophosphate synthase Peptidase_C26 PF07722.13 KXH60054.1 - 0.088 12.6 0.1 0.46 10.2 0.0 2.0 2 0 0 2 2 2 0 Peptidase C26 ODC_AZ PF02100.17 KXH60055.1 - 1.1e-43 147.8 0.4 1.6e-43 147.3 0.4 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme Yippee-Mis18 PF03226.14 KXH60056.1 - 1.6e-17 63.6 0.1 3.2e-17 62.7 0.1 1.5 1 1 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Mito_fiss_reg PF05308.11 KXH60056.1 - 2.5 8.1 13.7 4.2 7.4 13.7 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator SPATA3 PF15662.5 KXH60056.1 - 3.7 8.1 21.5 7.9 7.1 21.5 1.5 1 0 0 1 1 1 0 Spermatogenesis-associated protein 3 family Nop14 PF04147.12 KXH60056.1 - 7.1 4.7 9.8 11 4.1 9.8 1.3 1 0 0 1 1 1 0 Nop14-like family SOG2 PF10428.9 KXH60056.1 - 7.5 5.6 15.9 10 5.2 15.9 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Peptidase_M20 PF01546.28 KXH60057.1 - 8.8e-33 113.8 0.0 1.7e-32 112.8 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KXH60057.1 - 3e-13 49.6 0.0 4.7e-13 49.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain DWNN PF08783.11 KXH60058.1 - 1.1e-30 105.7 0.0 2e-30 104.9 0.0 1.4 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.6 KXH60058.1 - 1.9e-08 34.0 5.5 1.9e-08 34.0 5.5 1.6 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC PF00098.23 KXH60058.1 - 0.0013 18.7 0.9 0.0013 18.7 0.9 1.8 2 0 0 2 2 1 1 Zinc knuckle zf-C3HC4_2 PF13923.6 KXH60058.1 - 0.0019 18.0 10.3 0.0019 18.0 10.3 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.8 KXH60058.1 - 0.029 14.2 6.2 0.076 12.8 6.2 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DUF3332 PF11810.8 KXH60058.1 - 0.034 13.8 2.1 0.071 12.8 2.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3332) zf-RING_2 PF13639.6 KXH60058.1 - 0.056 13.8 7.4 0.12 12.7 7.4 1.6 1 0 0 1 1 1 0 Ring finger domain U-box PF04564.15 KXH60058.1 - 0.073 13.3 0.2 0.26 11.5 0.0 2.0 2 0 0 2 2 2 0 U-box domain zf-RING_4 PF14570.6 KXH60058.1 - 0.33 10.8 5.9 0.72 9.7 5.9 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.6 KXH60058.1 - 0.86 9.7 7.1 1.8 8.6 7.1 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KXH60058.1 - 0.97 9.6 10.4 2.5 8.3 10.4 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING FYVE_2 PF02318.16 KXH60058.1 - 1.1 9.5 5.5 0.17 12.1 1.0 1.9 3 0 0 3 3 2 0 FYVE-type zinc finger zf-C3HC4 PF00097.25 KXH60058.1 - 1.2 9.1 10.7 2.3 8.1 10.7 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Med3 PF11593.8 KXH60058.1 - 1.4 8.0 57.4 0.13 11.4 44.6 2.4 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal zf-RING_5 PF14634.6 KXH60058.1 - 9.1 6.3 13.7 0.87 9.6 8.2 2.1 2 1 0 2 2 2 0 zinc-RING finger domain ArsA_ATPase PF02374.15 KXH60059.1 - 1.3e-113 379.3 0.1 1.5e-113 379.1 0.1 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.6 KXH60059.1 - 2.3e-15 57.0 0.1 4.5e-14 52.8 0.0 2.4 2 1 0 2 2 2 1 AAA domain CbiA PF01656.23 KXH60059.1 - 3.3e-13 49.8 0.0 4.9e-13 49.2 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 KXH60059.1 - 6.4e-07 29.1 2.8 6.6e-05 22.5 1.0 2.6 2 1 0 2 2 2 2 NUBPL iron-transfer P-loop NTPase Fer4_NifH PF00142.18 KXH60059.1 - 1.6e-06 27.8 0.0 2.7e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.22 KXH60059.1 - 2.5e-06 27.3 0.1 0.00032 20.4 0.0 3.0 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain CBP_BcsQ PF06564.12 KXH60059.1 - 3.1e-05 23.6 0.0 8.1e-05 22.2 0.0 1.6 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsQ ATPase PF06745.13 KXH60059.1 - 0.043 13.1 0.5 0.23 10.8 0.0 2.0 2 1 0 2 2 2 0 KaiC PhoH PF02562.16 KXH60059.1 - 0.045 13.2 0.0 0.11 11.9 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 KXH60059.1 - 0.061 12.9 0.4 0.14 11.7 0.4 1.7 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KXH60059.1 - 0.085 12.1 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.6 KXH60059.1 - 0.091 13.3 0.0 0.24 11.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KXH60059.1 - 0.097 11.8 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_16 PF13191.6 KXH60059.1 - 0.11 12.9 0.0 0.18 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain IstB_IS21 PF01695.17 KXH60059.1 - 0.12 12.1 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.6 KXH60059.1 - 0.14 11.9 0.1 0.9 9.2 0.0 2.3 2 1 0 2 2 2 0 AAA domain MipZ PF09140.11 KXH60059.1 - 0.19 11.0 0.1 0.37 10.0 0.1 1.5 1 1 0 1 1 1 0 ATPase MipZ DUF4684 PF15736.5 KXH60060.1 - 0.093 11.4 0.1 0.12 11.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4684) SUR7 PF06687.12 KXH60061.1 - 4.4e-23 82.0 7.5 6.6e-23 81.5 7.5 1.3 1 0 0 1 1 1 1 SUR7/PalI family EphA2_TM PF14575.6 KXH60061.1 - 0.029 15.3 4.1 0.34 11.8 0.0 3.1 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain Claudin_2 PF13903.6 KXH60061.1 - 0.031 14.0 9.9 0.077 12.7 3.1 2.8 1 1 2 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction WBP-1 PF11669.8 KXH60061.1 - 0.057 14.1 0.0 0.14 12.8 0.0 1.6 1 0 0 1 1 1 0 WW domain-binding protein 1 PAG PF15347.6 KXH60061.1 - 0.2 10.6 0.0 0.29 10.1 0.0 1.2 1 0 0 1 1 1 0 Phosphoprotein associated with glycosphingolipid-enriched Herpes_gE PF02480.16 KXH60061.1 - 0.69 8.6 3.5 0.74 8.5 0.2 2.0 1 1 1 2 2 2 0 Alphaherpesvirus glycoprotein E LapA_dom PF06305.11 KXH60061.1 - 1.1 9.2 0.0 1.1 9.2 0.0 2.6 2 1 0 2 2 2 0 Lipopolysaccharide assembly protein A domain DUF1772 PF08592.11 KXH60061.1 - 9.2 6.6 11.2 2.1 8.7 7.1 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1772) Plk4_PB2 PF18409.1 KXH60062.1 - 0.019 15.7 0.3 5.2 7.8 0.2 2.3 2 0 0 2 2 2 0 Polo-like Kinase 4 Polo Box 2 Remorin_C PF03763.13 KXH60063.1 - 0.0092 15.8 1.0 0.019 14.8 1.0 1.5 1 0 0 1 1 1 1 Remorin, C-terminal region Transthyretin PF00576.21 KXH60066.1 - 7.9e-36 123.1 0.1 1.9e-35 121.8 0.1 1.6 1 1 0 1 1 1 1 HIUase/Transthyretin family FAD_binding_8 PF08022.12 KXH60067.1 - 3.2e-18 65.8 0.0 6.9e-18 64.7 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 KXH60067.1 - 1.2e-12 48.0 4.7 2.6e-12 47.0 4.7 1.6 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KXH60067.1 - 1e-08 35.4 0.0 1.2e-05 25.5 0.0 2.8 2 1 0 2 2 2 2 Ferric reductase NAD binding domain EF-hand_7 PF13499.6 KXH60067.1 - 0.0036 17.7 0.4 0.011 16.2 0.2 1.7 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 KXH60067.1 - 0.023 14.2 0.2 0.053 13.1 0.2 1.7 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.6 KXH60067.1 - 0.028 14.3 0.2 0.096 12.7 0.2 2.0 1 0 0 1 1 1 0 EF-hand domain EF-hand_8 PF13833.6 KXH60067.1 - 0.05 13.5 0.2 0.11 12.4 0.2 1.5 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_5 PF13202.6 KXH60067.1 - 0.12 11.9 0.1 0.28 10.7 0.1 1.6 1 0 0 1 1 1 0 EF hand MEDS PF14417.6 KXH60068.1 - 0.099 12.5 0.3 3.7 7.4 0.0 2.5 1 1 1 2 2 2 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain Baculo_IE-1 PF05290.11 KXH60068.1 - 1.1 9.2 8.8 3.6 7.5 0.4 3.0 1 1 2 3 3 3 0 Baculovirus immediate-early protein (IE-0) DUF1366 PF07104.11 KXH60068.1 - 2.8 7.7 12.9 0.1 12.3 1.8 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF1366) Synaptobrevin PF00957.21 KXH60068.1 - 3.1 7.7 9.3 0.34 10.7 2.8 2.6 2 1 0 2 2 2 0 Synaptobrevin DUF4446 PF14584.6 KXH60068.1 - 5.7 6.9 14.6 7.2 6.6 2.9 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF4446) Formyl_trans_N PF00551.19 KXH60070.1 - 2.1e-23 83.0 0.0 3e-23 82.5 0.0 1.2 1 0 0 1 1 1 1 Formyl transferase Glyco_transf_28 PF03033.20 KXH60072.1 - 2.8e-08 33.9 0.0 5.5e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 KXH60072.1 - 9.6e-05 21.4 0.0 0.00025 20.0 0.0 1.6 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 KXH60072.1 - 0.033 14.1 0.0 0.075 13.0 0.0 1.6 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain HET PF06985.11 KXH60095.1 - 8.7e-27 94.3 2.3 6.4e-25 88.2 2.3 2.1 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) GAF_2 PF13185.6 KXH60104.1 - 0.028 14.7 0.0 0.033 14.5 0.0 1.0 1 0 0 1 1 1 0 GAF domain Glyco_hydro_43 PF04616.14 KXH60115.1 - 9.6e-36 123.6 6.8 1.3e-35 123.1 6.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 KXH60115.1 - 3.4e-20 72.6 0.0 7e-20 71.6 0.0 1.5 2 0 0 2 2 2 1 Beta xylosidase C-terminal Concanavalin A-like domain PAP2 PF01569.21 KXH60116.1 - 1.9e-22 79.5 3.3 5.5e-22 78.0 0.4 2.5 2 1 0 2 2 2 1 PAP2 superfamily NAD_binding_6 PF08030.12 KXH60117.1 - 2.5e-18 66.7 0.0 4e-18 66.0 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 KXH60117.1 - 8.9e-15 54.9 13.3 1.1e-14 54.7 10.8 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KXH60117.1 - 5.2e-13 49.0 0.0 1.1e-12 48.0 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 KXH60117.1 - 0.0028 18.3 0.0 0.043 14.5 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FTR1 PF03239.14 KXH60118.1 - 2.2e-77 260.2 10.3 2.6e-77 260.0 10.3 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family DUF4293 PF14126.6 KXH60118.1 - 2 8.6 6.1 2 8.6 0.4 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4293) Cu-oxidase_3 PF07732.15 KXH60119.1 - 1.3e-43 147.8 6.5 1.3e-41 141.3 0.9 4.0 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 KXH60119.1 - 6.3e-40 136.1 4.9 9.7e-37 125.8 0.1 2.8 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.22 KXH60119.1 - 1.2e-38 132.7 0.5 8.7e-36 123.4 0.3 2.5 2 0 0 2 2 2 2 Multicopper oxidase Podoplanin PF05808.11 KXH60120.1 - 0.028 14.5 0.4 0.049 13.7 0.4 1.3 1 0 0 1 1 1 0 Podoplanin Pectate_lyase PF03211.13 KXH60121.1 - 2.9e-59 200.1 1.0 3.9e-53 180.0 1.3 2.1 1 1 1 2 2 2 2 Pectate lyase Sugar_tr PF00083.24 KXH60122.1 - 2.9e-86 290.1 24.1 3.4e-86 289.9 24.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH60122.1 - 1e-19 70.7 38.8 2.2e-14 53.2 12.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MAP65_ASE1 PF03999.12 KXH60123.1 - 0.79 8.4 4.1 1.1 7.9 4.1 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) DUF5597 PF18120.1 KXH60124.1 - 5.6e-27 94.5 0.1 9.1e-27 93.8 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5597) Glyco_hydro_42 PF02449.15 KXH60124.1 - 4.5e-10 39.4 0.0 7.5e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 Beta-galactosidase Glyco_hydro_35 PF01301.19 KXH60124.1 - 2.2e-05 24.2 0.0 0.0029 17.3 0.0 2.1 2 0 0 2 2 2 2 Glycosyl hydrolases family 35 Glyco_hydro_10 PF00331.20 KXH60124.1 - 0.11 11.7 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 10 GFA PF04828.14 KXH60125.1 - 7.5e-11 42.2 0.4 1.2e-10 41.6 0.4 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme SLATT_fungal PF18142.1 KXH60126.1 - 2.3e-23 82.5 0.1 3e-23 82.1 0.1 1.2 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain HD_5 PF13487.6 KXH60126.1 - 0.0092 16.2 0.0 0.022 15.0 0.0 1.6 1 0 0 1 1 1 1 HD domain Lipase_GDSL_2 PF13472.6 KXH60127.1 - 2.4e-17 63.9 0.1 3.4e-17 63.4 0.1 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KXH60127.1 - 1.8e-12 47.6 0.1 2.4e-12 47.3 0.1 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 KXH60127.1 - 0.0014 18.8 0.1 0.002 18.3 0.1 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family DUF4131 PF13567.6 KXH60129.1 - 0.0097 15.6 0.5 0.045 13.4 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4131) Sigma_reg_N PF13800.6 KXH60129.1 - 5.6 7.3 7.2 1.2 9.5 0.0 3.3 4 0 0 4 4 4 0 Sigma factor regulator N-terminal SF3A2 PF16835.5 KXH60130.1 - 2.2e-34 117.7 0.1 3.6e-34 117.0 0.1 1.3 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 KXH60130.1 - 3.4e-06 27.2 0.9 6.9e-06 26.3 0.9 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type CactinC_cactus PF09732.9 KXH60130.1 - 6.1e-05 22.9 0.3 8.9e-05 22.4 0.3 1.2 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein PRP4 PF08799.11 KXH60130.1 - 0.057 13.0 1.5 0.11 12.1 1.5 1.5 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like Tim54 PF11711.8 KXH60132.1 - 4.8e-141 469.9 0.5 5.9e-141 469.6 0.5 1.1 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 FAM110_C PF14160.6 KXH60132.1 - 0.083 14.0 0.4 29 5.8 0.0 2.4 2 0 0 2 2 2 0 Centrosome-associated C terminus Nefa_Nip30_N PF10187.9 KXH60133.1 - 6.1e-28 97.3 12.9 6.1e-28 97.3 12.9 1.6 2 0 0 2 2 2 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 DUF4407 PF14362.6 KXH60133.1 - 0.74 9.1 10.5 0.94 8.8 10.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) APG6_N PF17675.1 KXH60133.1 - 1.6 9.3 10.4 2 9.0 10.4 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region p450 PF00067.22 KXH60217.1 - 0.00018 20.4 0.0 0.00018 20.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF5482 PF17579.2 KXH60217.1 - 0.055 13.4 0.0 0.059 13.2 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5482) Lin-8 PF03353.15 KXH60253.1 - 0.56 9.7 4.7 0.64 9.5 4.7 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SH3_1 PF00018.28 KXH60282.1 - 3.5e-13 48.9 0.0 6e-13 48.2 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KXH60282.1 - 2.7e-08 33.5 0.0 4e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KXH60282.1 - 9.3e-06 25.2 0.0 1.4e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain MSA-2c PF12238.8 KXH60282.1 - 6.9 6.6 8.4 9.5 6.2 8.4 1.2 1 0 0 1 1 1 0 Merozoite surface antigen 2c Membr_traf_MHD PF10540.9 KXH60283.1 - 8.8e-19 68.1 0.3 6.2e-10 39.4 0.2 2.6 1 1 1 2 2 2 2 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.30 KXH60283.1 - 4.2e-17 62.3 0.0 1e-16 61.1 0.0 1.7 1 0 0 1 1 1 1 C2 domain DUF810 PF05664.11 KXH60283.1 - 2.2e-06 26.5 0.2 2.2e-06 26.5 0.2 1.9 3 0 0 3 3 3 1 Plant family of unknown function (DUF810) TFIIF_alpha PF05793.12 KXH60288.1 - 0.0012 17.5 14.4 0.0019 16.9 14.4 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SDA1 PF05285.12 KXH60288.1 - 0.02 14.4 11.9 0.011 15.3 7.0 2.2 2 0 0 2 2 2 0 SDA1 YL1 PF05764.13 KXH60288.1 - 0.057 13.5 10.4 0.12 12.5 10.4 1.6 1 0 0 1 1 1 0 YL1 nuclear protein DUF4637 PF15470.6 KXH60288.1 - 0.11 12.2 6.9 0.26 11.0 6.9 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Nop14 PF04147.12 KXH60288.1 - 0.15 10.3 8.4 0.19 9.9 8.4 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 KXH60288.1 - 0.19 10.0 7.6 0.25 9.6 7.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Sporozoite_P67 PF05642.11 KXH60288.1 - 0.59 8.2 8.5 0.91 7.5 8.5 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PBP1_TM PF14812.6 KXH60288.1 - 0.99 9.8 10.7 3.4 8.1 10.7 2.0 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Pox_Ag35 PF03286.14 KXH60288.1 - 1.7 8.4 10.4 3.8 7.2 10.4 1.6 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Paf1 PF03985.13 KXH60288.1 - 2.5 7.0 11.6 3.9 6.4 11.6 1.2 1 0 0 1 1 1 0 Paf1 FAM176 PF14851.6 KXH60288.1 - 4.8 6.8 5.4 9.3 5.9 5.4 1.5 1 0 0 1 1 1 0 FAM176 family CobT PF06213.12 KXH60288.1 - 5.4 6.3 15.6 10 5.4 15.6 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Glyco_hydro_3 PF00933.21 KXH60289.1 - 1e-44 153.2 0.0 1.6e-44 152.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 KXH60289.1 - 3.8e-41 141.3 0.1 1.4e-40 139.5 0.0 2.0 2 1 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 KXH60289.1 - 9e-24 83.4 0.1 1.7e-23 82.5 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain CARDB PF07705.11 KXH60289.1 - 0.046 14.0 0.0 0.13 12.6 0.0 1.7 1 0 0 1 1 1 0 CARDB Lipase_3 PF01764.25 KXH60290.1 - 1.2e-35 122.4 0.0 2e-35 121.7 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_8 PF06259.12 KXH60290.1 - 0.0032 17.1 0.0 0.0073 16.0 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase Hydrolase_4 PF12146.8 KXH60290.1 - 0.0074 15.6 0.0 0.015 14.6 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KXH60290.1 - 0.011 16.3 0.1 0.014 16.0 0.1 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family SNF2_N PF00176.23 KXH60291.1 - 6.4e-50 169.8 0.2 6.1e-45 153.5 0.0 2.6 3 0 0 3 3 3 2 SNF2 family N-terminal domain Helicase_C PF00271.31 KXH60291.1 - 9.8e-17 61.3 0.0 9.9e-16 58.1 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXH60291.1 - 9.5e-09 35.5 1.2 2e-08 34.5 0.1 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.25 KXH60291.1 - 9.6e-07 28.6 5.5 9.6e-07 28.6 5.5 1.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) AAA_34 PF13872.6 KXH60291.1 - 3.2e-05 23.0 0.0 0.00012 21.1 0.0 1.9 2 0 0 2 2 2 1 P-loop containing NTP hydrolase pore-1 zf-C3HC4_2 PF13923.6 KXH60291.1 - 0.00015 21.5 6.3 0.00015 21.5 6.3 1.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KXH60291.1 - 0.00055 19.7 6.6 0.00055 19.7 6.6 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXH60291.1 - 0.0013 19.0 7.5 0.0013 19.0 7.5 2.5 2 0 0 2 2 2 1 Ring finger domain AT_hook PF02178.19 KXH60291.1 - 0.13 12.2 22.4 3.2 7.9 1.9 4.3 3 0 0 3 3 3 0 AT hook motif zf-RING_UBOX PF13445.6 KXH60291.1 - 0.64 10.1 6.6 1.9 8.6 6.6 1.9 1 0 0 1 1 1 0 RING-type zinc-finger Zn_Tnp_IS91 PF14319.6 KXH60291.1 - 0.7 10.0 7.3 1 9.4 0.7 2.5 2 0 0 2 2 2 0 Transposase zinc-binding domain SPT6_acidic PF14632.6 KXH60291.1 - 7.8 7.2 24.6 0.056 14.0 4.8 3.4 2 1 1 3 3 3 0 Acidic N-terminal SPT6 LRR_8 PF13855.6 KXH60292.1 - 0.086 12.6 0.1 0.76 9.6 0.1 2.6 3 0 0 3 3 3 0 Leucine rich repeat LRR_4 PF12799.7 KXH60292.1 - 0.26 11.8 3.6 50 4.5 0.3 4.9 6 1 1 7 7 7 0 Leucine Rich repeats (2 copies) DUF4604 PF15377.6 KXH60292.1 - 3.2 8.2 20.6 0.85 10.0 17.2 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4604) DHHC PF01529.20 KXH60293.1 - 1.1e-37 129.1 9.7 1.9e-37 128.4 9.7 1.4 1 0 0 1 1 1 1 DHHC palmitoyltransferase DUF4064 PF13273.6 KXH60293.1 - 0.088 13.1 0.1 0.088 13.1 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) FtsX PF02687.21 KXH60293.1 - 7.2 7.2 8.2 55 4.3 8.2 2.2 1 1 1 2 2 2 0 FtsX-like permease family Peptidase_M16_C PF05193.21 KXH60294.1 - 2.8e-18 66.6 0.0 5.5e-15 55.8 0.0 2.7 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KXH60294.1 - 1.8e-06 28.0 0.1 1.1e-05 25.4 0.0 2.1 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) M16C_assoc PF08367.11 KXH60294.1 - 0.001 18.2 3.8 0.77 8.8 3.4 2.3 2 0 0 2 2 2 2 Peptidase M16C associated Sporozoite_P67 PF05642.11 KXH60294.1 - 0.43 8.6 4.4 0.62 8.1 4.4 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Zw10 PF06248.13 KXH60295.1 - 2.3e-07 29.8 1.0 5.3e-06 25.3 1.4 2.6 2 1 0 2 2 2 1 Centromere/kinetochore Zw10 CorA PF01544.18 KXH60295.1 - 0.013 14.8 2.1 0.037 13.3 2.1 1.7 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Dsl1_C PF11989.8 KXH60295.1 - 0.034 13.9 0.0 0.085 12.6 0.0 1.6 1 0 0 1 1 1 0 Retrograde transport protein Dsl1 C terminal Com_YlbF PF06133.11 KXH60295.1 - 0.1 13.2 1.9 7.1 7.3 0.5 3.2 2 0 0 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA CDC45 PF02724.14 KXH60295.1 - 0.28 9.4 10.4 0.025 12.9 5.7 1.5 2 0 0 2 2 2 0 CDC45-like protein Nop14 PF04147.12 KXH60295.1 - 0.43 8.7 14.0 0.72 8.0 14.0 1.2 1 0 0 1 1 1 0 Nop14-like family PI-PLC-X PF00388.19 KXH60296.1 - 7.2e-59 197.5 0.0 1.4e-58 196.6 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 KXH60296.1 - 1.2e-42 144.8 0.1 3.5e-42 143.4 0.1 1.9 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 KXH60296.1 - 4.1e-09 36.7 0.1 2.5e-08 34.2 0.0 2.3 2 1 0 2 2 2 1 C2 domain PH_12 PF16457.5 KXH60296.1 - 0.00046 20.7 0.7 0.003 18.1 0.7 2.4 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 KXH60296.1 - 0.021 15.3 2.4 0.075 13.5 0.9 2.5 2 0 0 2 2 2 0 PH domain EF-hand_like PF09279.11 KXH60296.1 - 0.035 14.6 0.0 0.091 13.3 0.0 1.7 1 0 0 1 1 1 0 Phosphoinositide-specific phospholipase C, efhand-like PH_11 PF15413.6 KXH60296.1 - 0.45 11.0 5.1 0.85 10.1 3.1 2.5 2 1 0 2 2 2 0 Pleckstrin homology domain Rb_C PF08934.10 KXH60299.1 - 1.3 8.8 5.4 1.9 8.2 5.4 1.3 1 0 0 1 1 1 0 Rb C-terminal domain BCS1_N PF08740.11 KXH60300.1 - 1.3e-49 168.8 0.4 2e-49 168.1 0.4 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 KXH60300.1 - 3.8e-15 56.5 0.0 1.5e-06 28.6 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 KXH60300.1 - 0.027 14.1 0.0 0.064 12.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain RuvB_N PF05496.12 KXH60300.1 - 0.032 14.0 0.0 0.055 13.2 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KXH60300.1 - 0.15 12.1 0.0 0.38 10.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ATPase PF06745.13 KXH60300.1 - 0.15 11.4 0.0 0.3 10.4 0.0 1.4 1 0 0 1 1 1 0 KaiC Pheromone PF08015.11 KXH60300.1 - 1.1 10.4 5.5 3.7 8.7 5.5 1.9 1 0 0 1 1 1 0 Fungal mating-type pheromone Tau95 PF09734.9 KXH60301.1 - 1.4e-35 123.1 0.2 3.1e-35 122.0 0.2 1.6 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Tau95_N PF17682.1 KXH60301.1 - 3.3e-35 121.0 0.0 6.5e-35 120.1 0.0 1.5 1 0 0 1 1 1 1 Tau95 Triple barrel domain B56 PF01603.20 KXH60302.1 - 9.7e-193 640.8 4.5 1.2e-192 640.5 4.5 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Sec7_N PF12783.7 KXH60302.1 - 0.0007 19.5 1.7 0.31 10.9 0.0 2.4 2 0 0 2 2 2 2 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF4748 PF15932.5 KXH60303.1 - 1.1e-24 85.9 0.8 1.1e-24 85.9 0.8 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4748) CTD_bind PF04818.13 KXH60303.1 - 1.7e-14 54.4 0.1 1.4e-13 51.4 0.0 2.4 2 0 0 2 2 2 1 RNA polymerase II-binding domain. Exo_endo_phos PF03372.23 KXH60304.1 - 2.7e-10 40.2 0.1 4.5e-10 39.4 0.1 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF2442 PF10387.9 KXH60304.1 - 0.092 13.1 0.0 7.9 6.9 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2442) Orn_Arg_deC_N PF02784.16 KXH60305.1 - 1e-83 280.5 0.0 1.4e-83 280.1 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 KXH60305.1 - 4.2e-19 68.6 0.0 1.4e-18 66.9 0.0 1.7 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain M16C_assoc PF08367.11 KXH60306.1 - 7.9e-85 284.0 0.0 1.1e-84 283.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 KXH60306.1 - 8.5e-34 117.2 0.0 4e-22 79.1 0.0 3.1 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KXH60306.1 - 5.8e-09 36.1 0.1 1.9e-07 31.1 0.0 3.0 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) UvrA_inter PF17760.1 KXH60306.1 - 0.0085 16.2 0.1 0.044 13.9 0.1 2.1 2 0 0 2 2 2 1 UvrA interaction domain Taxilin PF09728.9 KXH60307.1 - 5.8e-89 298.3 59.1 5.8e-89 298.3 59.1 1.6 2 0 0 2 2 2 1 Myosin-like coiled-coil protein DUF4810 PF16068.5 KXH60307.1 - 0.003 18.0 0.1 0.003 18.0 0.1 4.2 5 0 0 5 5 5 1 Domain of unknown function (DUF4810) Cep57_CLD_2 PF14197.6 KXH60307.1 - 0.0035 17.4 1.2 0.0035 17.4 1.2 5.4 3 2 3 6 6 6 1 Centrosome localisation domain of PPC89 DUF1678 PF07913.11 KXH60307.1 - 0.0073 16.1 1.1 0.018 14.8 1.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1678) Syntaxin PF00804.25 KXH60307.1 - 0.012 15.3 5.0 0.012 15.3 5.0 4.9 3 1 3 6 6 6 0 Syntaxin HNF-1B_C PF04812.13 KXH60308.1 - 0.045 13.6 0.4 0.095 12.5 0.4 1.5 1 0 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), beta isoform C terminus NMO PF03060.15 KXH60309.1 - 8.6e-49 166.7 1.2 1.2e-48 166.2 1.2 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KXH60309.1 - 2.9e-07 29.8 0.8 3.3e-06 26.4 0.8 2.1 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KXH60309.1 - 0.01 14.9 2.9 0.017 14.1 2.9 1.3 1 0 0 1 1 1 0 FMN-dependent dehydrogenase IF2_N PF04760.15 KXH60309.1 - 0.18 11.6 0.0 0.45 10.4 0.0 1.7 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region Pol_alpha_B_N PF08418.10 KXH60311.1 - 7.9e-88 294.6 0.1 1e-87 294.2 0.1 1.1 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.16 KXH60311.1 - 1.1e-40 139.3 0.1 1.5e-40 138.8 0.1 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B MFAP1 PF06991.11 KXH60312.1 - 3.1e-69 233.1 27.4 3.1e-69 233.1 27.4 3.1 3 1 0 3 3 3 1 Microfibril-associated/Pre-mRNA processing Alb1 PF09135.11 KXH60313.1 - 1.2e-28 100.1 18.4 1.2e-28 100.1 18.4 1.5 2 0 0 2 2 2 1 Alb1 CDC27 PF09507.10 KXH60313.1 - 2.3 7.5 21.8 2.9 7.2 21.8 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 UCH PF00443.29 KXH60314.1 - 1.2e-36 126.5 0.0 2.2e-36 125.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KXH60314.1 - 2e-07 30.9 0.1 1.9e-06 27.7 0.1 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Cytochrom_B_N_2 PF13631.6 KXH60314.1 - 0.11 12.5 0.1 0.21 11.6 0.1 1.4 1 0 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB TENA_THI-4 PF03070.16 KXH60315.1 - 0.099 12.4 0.0 1.4 8.7 0.0 2.2 2 0 0 2 2 2 0 TENA/THI-4/PQQC family TPT PF03151.16 KXH60316.1 - 1.3e-29 103.5 23.8 1.6e-29 103.2 23.8 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 KXH60316.1 - 0.0002 20.7 24.0 0.00029 20.1 24.0 1.2 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 KXH60316.1 - 0.0052 17.0 42.3 0.021 15.0 15.4 2.7 3 0 0 3 3 3 2 EamA-like transporter family Glyco_transf_17 PF04724.13 KXH60317.1 - 1.2e-50 172.5 1.4 8.7e-50 169.7 1.4 1.9 1 1 0 1 1 1 1 Glycosyltransferase family 17 COMPASS-Shg1 PF05205.12 KXH60318.1 - 8.2e-26 90.7 0.1 8.2e-26 90.7 0.1 2.7 3 0 0 3 3 3 1 COMPASS (Complex proteins associated with Set1p) component shg1 PGA2 PF07543.12 KXH60319.1 - 3.8e-38 130.6 0.3 4.4e-38 130.4 0.3 1.0 1 0 0 1 1 1 1 Protein trafficking PGA2 CENP-S PF15630.6 KXH60320.1 - 1.5e-34 118.2 0.0 2.2e-34 117.7 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 KXH60320.1 - 4.1e-07 30.1 0.0 4.7e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Bromo_TP PF07524.13 KXH60320.1 - 0.00043 20.2 0.1 0.0043 17.0 0.0 2.0 1 1 1 2 2 2 1 Bromodomain associated TFIID-18kDa PF02269.16 KXH60320.1 - 0.0037 17.2 0.0 0.0052 16.8 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Histone PF00125.24 KXH60320.1 - 0.0047 17.3 0.1 0.0066 16.8 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 FliL PF03748.14 KXH60320.1 - 0.013 16.0 0.2 4.8 7.8 0.0 2.1 1 1 1 2 2 2 0 Flagellar basal body-associated protein FliL DUF956 PF06115.11 KXH60320.1 - 0.087 12.5 0.0 0.13 12.0 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF956) SF1-HH PF16275.5 KXH60321.1 - 0.091 13.1 0.1 0.26 11.6 0.1 1.7 1 0 0 1 1 1 0 Splicing factor 1 helix-hairpin domain Utp13 PF08625.11 KXH60322.1 - 4.6e-51 172.5 0.3 7.2e-51 171.8 0.3 1.3 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain WD40 PF00400.32 KXH60322.1 - 1.9e-48 161.4 18.2 0.00013 22.7 0.0 11.7 11 1 0 11 11 11 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXH60322.1 - 2.3e-12 47.0 2.7 1.7 9.0 0.0 8.1 6 2 1 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KXH60322.1 - 1.2e-06 27.5 2.6 0.14 10.7 0.0 5.0 4 2 2 6 6 6 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 KXH60322.1 - 0.002 17.0 1.8 6.2 5.5 0.0 4.7 4 2 1 5 5 5 2 Nup133 N terminal like NQRA PF05896.11 KXH60322.1 - 0.093 12.2 0.0 1.1 8.6 0.0 2.1 2 0 0 2 2 2 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) PNP_UDP_1 PF01048.20 KXH60323.1 - 5.1e-11 42.3 1.0 2.7e-10 39.9 1.0 2.0 1 1 0 1 1 1 1 Phosphorylase superfamily TRAF_BIRC3_bd PF16673.5 KXH60323.1 - 0.073 12.9 0.2 0.23 11.3 0.2 1.8 1 0 0 1 1 1 0 TNF receptor-associated factor BIRC3 binding domain UCH PF00443.29 KXH60324.1 - 4.9e-25 88.5 0.0 7.4e-25 87.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KXH60324.1 - 2.2e-12 47.1 1.6 3.7e-12 46.4 0.3 1.9 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 KXH60324.1 - 0.018 14.6 0.0 0.078 12.6 0.0 2.0 2 0 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase IF4E PF01652.18 KXH60325.1 - 7.7e-50 168.8 0.1 1.1e-49 168.3 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E ANAPC3 PF12895.7 KXH60326.1 - 8.5e-26 90.0 21.2 2.4e-23 82.1 1.1 5.8 4 2 4 8 8 8 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 KXH60326.1 - 2.1e-23 81.1 12.2 4.2e-05 23.2 0.9 9.7 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_19 PF14559.6 KXH60326.1 - 3.3e-22 78.8 19.7 0.00081 19.9 0.0 7.7 5 2 3 8 8 8 7 Tetratricopeptide repeat TPR_2 PF07719.17 KXH60326.1 - 4.7e-21 73.2 23.6 0.0005 20.0 0.4 10.5 12 0 0 12 12 11 5 Tetratricopeptide repeat TPR_8 PF13181.6 KXH60326.1 - 2.7e-18 64.6 5.4 0.0078 16.3 0.3 9.3 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_12 PF13424.6 KXH60326.1 - 5e-16 58.7 19.3 0.00034 20.9 0.1 9.0 5 2 3 8 8 8 6 Tetratricopeptide repeat TPR_14 PF13428.6 KXH60326.1 - 8.2e-15 54.2 18.3 0.16 12.9 0.0 9.8 7 4 2 9 9 9 4 Tetratricopeptide repeat TPR_16 PF13432.6 KXH60326.1 - 2.1e-11 44.3 17.3 0.055 14.1 0.2 8.6 6 3 2 8 8 8 4 Tetratricopeptide repeat TPR_10 PF13374.6 KXH60326.1 - 1.3e-07 31.3 13.4 0.14 12.1 0.0 8.4 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_6 PF13174.6 KXH60326.1 - 1.7e-06 28.3 11.6 0.49 11.2 0.2 7.9 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_7 PF13176.6 KXH60326.1 - 3.1e-06 26.8 18.5 9.3 6.5 0.1 8.9 10 0 0 10 10 9 1 Tetratricopeptide repeat TPR_9 PF13371.6 KXH60326.1 - 5.4e-05 23.3 4.3 2.2 8.5 0.2 5.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_15 PF13429.6 KXH60326.1 - 6.3e-05 22.3 6.3 0.19 10.9 0.0 5.4 3 2 0 5 5 5 1 Tetratricopeptide repeat TPR_4 PF07721.14 KXH60326.1 - 0.00031 21.1 3.3 2.2 9.1 0.0 5.9 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 KXH60326.1 - 0.00056 19.5 13.4 1.3 8.8 0.0 6.3 8 0 0 8 8 8 3 TPR repeat Coatomer_E PF04733.14 KXH60326.1 - 0.019 14.4 0.5 19 4.5 0.0 3.8 3 1 0 4 4 4 0 Coatomer epsilon subunit TPR_21 PF09976.9 KXH60326.1 - 0.072 12.8 6.3 1.3 8.6 0.5 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat-like domain TPR_17 PF13431.6 KXH60326.1 - 0.1 13.1 6.7 74 4.1 0.0 6.9 8 0 0 8 8 8 0 Tetratricopeptide repeat HET PF06985.11 KXH60327.1 - 1.2e-21 77.6 0.0 3.1e-21 76.3 0.0 1.7 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) AMP-binding PF00501.28 KXH60328.1 - 9.3e-43 146.4 0.0 3.1e-42 144.6 0.0 1.7 1 1 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 KXH60328.1 - 7.9e-05 22.5 0.6 0.00017 21.4 0.0 1.9 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 KXH60328.1 - 0.03 15.3 0.0 0.063 14.3 0.0 1.5 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain RecG_N PF17190.4 KXH60330.1 - 0.036 14.8 0.1 1.5 9.6 0.1 2.4 2 0 0 2 2 2 0 RecG N-terminal helical domain Cep57_CLD PF14073.6 KXH60331.1 - 0.00097 19.2 5.9 0.0017 18.4 5.9 1.4 1 1 0 1 1 1 1 Centrosome localisation domain of Cep57 XhlA PF10779.9 KXH60331.1 - 0.0012 18.9 2.8 0.0012 18.9 2.8 1.7 2 0 0 2 2 2 1 Haemolysin XhlA DUF1192 PF06698.11 KXH60331.1 - 0.0015 18.5 3.0 0.012 15.7 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1192) APG6_N PF17675.1 KXH60331.1 - 0.0028 18.2 6.9 0.0035 17.9 6.9 1.2 1 0 0 1 1 1 1 Apg6 coiled-coil region HrpB7 PF09486.10 KXH60331.1 - 0.0064 16.9 8.3 0.0097 16.3 8.3 1.4 1 1 0 1 1 1 1 Bacterial type III secretion protein (HrpB7) TRAF_BIRC3_bd PF16673.5 KXH60331.1 - 0.045 13.6 1.3 0.081 12.7 1.3 1.4 1 0 0 1 1 1 0 TNF receptor-associated factor BIRC3 binding domain AAA_13 PF13166.6 KXH60331.1 - 0.069 11.8 3.9 0.076 11.7 3.9 1.1 1 0 0 1 1 1 0 AAA domain DUF775 PF05603.12 KXH60331.1 - 0.077 12.5 0.7 0.089 12.3 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF775) ATG16 PF08614.11 KXH60331.1 - 0.096 12.9 7.4 0.12 12.6 7.4 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) MerR-DNA-bind PF09278.11 KXH60331.1 - 0.14 12.7 5.3 4.1 8.0 0.3 2.2 1 1 1 2 2 2 0 MerR, DNA binding CENP-H PF05837.12 KXH60331.1 - 0.17 12.3 5.9 0.27 11.7 5.9 1.5 1 1 0 1 1 1 0 Centromere protein H (CENP-H) Spc7 PF08317.11 KXH60331.1 - 0.19 10.6 6.3 0.22 10.3 6.3 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein CC2-LZ PF16516.5 KXH60331.1 - 0.35 11.3 6.2 0.071 13.5 2.9 1.5 2 0 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator DUF724 PF05266.14 KXH60331.1 - 0.45 10.3 3.4 0.61 9.9 3.4 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF724) UPF0515 PF15135.6 KXH60331.1 - 0.73 9.1 3.2 0.83 8.9 3.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein UPF0515 DUF4407 PF14362.6 KXH60331.1 - 0.87 8.9 7.2 2.5 7.4 7.2 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Rnk_N PF14760.6 KXH60331.1 - 1.1 9.7 7.4 5.6 7.5 0.9 2.8 2 1 0 2 2 2 0 Rnk N-terminus Cep57_CLD_2 PF14197.6 KXH60331.1 - 1.7 8.8 8.3 0.47 10.6 3.6 2.4 2 1 0 2 2 2 0 Centrosome localisation domain of PPC89 DivIC PF04977.15 KXH60331.1 - 1.7 8.5 8.5 0.22 11.3 2.2 2.4 1 1 2 3 3 3 0 Septum formation initiator Metal_resist PF13801.6 KXH60332.1 - 0.02 15.1 2.6 0.056 13.6 2.6 1.7 1 0 0 1 1 1 0 Heavy-metal resistance LCM PF04072.14 KXH60332.1 - 0.025 14.5 0.2 0.025 14.5 0.2 2.2 2 1 1 3 3 3 0 Leucine carboxyl methyltransferase FadA PF09403.10 KXH60332.1 - 2.5 8.6 8.9 0.15 12.6 3.0 2.1 2 0 0 2 2 2 0 Adhesion protein FadA BRE1 PF08647.11 KXH60333.1 - 0.004 17.2 2.7 0.0063 16.6 2.7 1.2 1 0 0 1 1 1 1 BRE1 E3 ubiquitin ligase Perilipin PF03036.16 KXH60333.1 - 0.017 14.2 0.6 0.021 13.9 0.6 1.0 1 0 0 1 1 1 0 Perilipin family rRNA_proc-arch PF13234.6 KXH60333.1 - 0.026 14.5 0.2 0.034 14.1 0.2 1.1 1 0 0 1 1 1 0 rRNA-processing arch domain DUF1664 PF07889.12 KXH60333.1 - 0.026 14.6 0.0 0.038 14.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) CCDC-167 PF15188.6 KXH60333.1 - 0.06 13.7 0.6 0.1 13.0 0.2 1.7 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 DUF1296 PF06972.11 KXH60333.1 - 0.067 13.3 0.1 0.12 12.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1296) MT PF12777.7 KXH60333.1 - 0.082 11.9 0.0 0.1 11.6 0.0 1.1 1 0 0 1 1 1 0 Microtubule-binding stalk of dynein motor Octopine_DH PF02317.17 KXH60333.1 - 0.13 12.3 0.1 0.17 12.0 0.1 1.1 1 0 0 1 1 1 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain Tropomyosin_1 PF12718.7 KXH60333.1 - 0.14 12.3 4.3 0.26 11.5 4.3 1.4 1 0 0 1 1 1 0 Tropomyosin like YabA PF06156.13 KXH60333.1 - 0.17 12.5 0.8 0.29 11.8 0.7 1.4 1 1 0 1 1 1 0 Initiation control protein YabA DUF1635 PF07795.11 KXH60333.1 - 0.18 11.6 5.1 3.9 7.3 5.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1635) UPF0242 PF06785.11 KXH60333.1 - 0.29 11.2 4.0 0.41 10.7 4.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Lge1 PF11488.8 KXH60333.1 - 0.45 10.7 3.9 0.64 10.3 1.9 2.1 1 1 1 2 2 2 0 Transcriptional regulatory protein LGE1 THOC7 PF05615.13 KXH60334.1 - 0.011 16.1 7.2 0.011 16.1 7.2 4.7 1 1 3 4 4 4 0 Tho complex subunit 7 DUF4279 PF14106.6 KXH60334.1 - 0.36 11.0 5.9 0.99 9.6 0.1 3.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4279) Abhydrolase_1 PF00561.20 KXH60335.1 - 4.8e-20 72.3 0.0 1.4e-19 70.8 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXH60335.1 - 1.8e-11 45.1 0.3 2.3e-11 44.8 0.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXH60335.1 - 0.00038 19.8 0.0 0.00052 19.4 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Fungal_trans_2 PF11951.8 KXH60336.1 - 3e-24 85.6 0.8 7.9e-24 84.2 0.8 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Methyltransf_23 PF13489.6 KXH60338.1 - 9.6e-24 84.1 0.0 1.4e-23 83.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH60338.1 - 7.9e-10 39.3 0.0 4.3e-09 37.0 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH60338.1 - 1.4e-07 32.1 0.1 9.1e-07 29.6 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH60338.1 - 1.4e-06 28.2 0.0 8.8e-06 25.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH60338.1 - 7.2e-06 26.6 0.0 1.4e-05 25.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXH60338.1 - 0.045 13.3 0.0 0.079 12.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain CMAS PF02353.20 KXH60338.1 - 0.073 12.4 0.0 0.18 11.1 0.0 1.5 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_4 PF02390.17 KXH60338.1 - 0.12 11.9 0.0 0.41 10.1 0.0 1.8 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_2 PF00891.18 KXH60338.1 - 0.16 11.2 0.0 4.2 6.6 0.0 2.5 3 0 0 3 3 3 0 O-methyltransferase domain Methyltransf_16 PF10294.9 KXH60338.1 - 0.21 11.3 0.0 0.32 10.7 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase Fungal_trans PF04082.18 KXH60339.1 - 8.9e-35 120.0 0.8 8.9e-35 120.0 0.8 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH60339.1 - 5.9e-08 32.7 9.6 1e-07 31.9 9.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain POT1 PF02765.17 KXH60341.1 - 3.7e-08 33.3 0.0 6.9e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 FMO-like PF00743.19 KXH60342.1 - 4.3e-41 140.9 0.0 7.2e-24 84.1 0.0 3.1 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KXH60342.1 - 7.8e-17 61.5 0.0 1.6e-09 37.4 0.0 3.2 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXH60342.1 - 5.6e-14 52.1 0.0 1e-12 47.9 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXH60342.1 - 1.5e-10 40.7 0.1 3e-08 33.2 0.0 2.5 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KXH60342.1 - 4e-10 39.9 4.3 1.5e-07 31.5 0.1 4.1 3 2 1 4 4 4 1 FAD-NAD(P)-binding DAO PF01266.24 KXH60342.1 - 4.8e-10 39.5 0.1 3.4e-05 23.6 0.1 4.0 4 0 0 4 4 4 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXH60342.1 - 1.1e-08 35.1 0.0 3.1e-07 30.5 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KXH60342.1 - 4.7e-08 32.6 0.1 7.8e-05 22.0 0.1 2.2 2 0 0 2 2 2 2 Thi4 family Pyr_redox PF00070.27 KXH60342.1 - 1.1e-05 25.9 0.2 0.085 13.4 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KXH60342.1 - 1.7e-05 24.3 0.1 0.003 16.9 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 KXH60342.1 - 2.6e-05 23.1 0.2 0.026 13.2 0.7 2.4 3 0 0 3 3 3 2 HI0933-like protein Amino_oxidase PF01593.24 KXH60342.1 - 3.5e-05 23.3 0.7 0.004 16.5 0.0 3.1 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase Glu_dehyd_C PF16912.5 KXH60342.1 - 4.9e-05 22.9 0.0 0.11 11.9 0.0 2.2 2 0 0 2 2 2 2 Glucose dehydrogenase C-terminus FAD_binding_2 PF00890.24 KXH60342.1 - 0.00078 18.6 0.2 0.051 12.6 0.2 2.7 3 0 0 3 3 3 1 FAD binding domain Lycopene_cycl PF05834.12 KXH60342.1 - 0.00096 18.3 0.1 0.56 9.2 0.0 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein Shikimate_DH PF01488.20 KXH60342.1 - 0.0017 18.4 0.0 0.24 11.5 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 KXH60342.1 - 0.0019 17.6 0.0 0.44 9.9 0.0 2.2 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 KXH60342.1 - 0.009 16.3 0.2 0.27 11.5 0.0 2.4 2 0 0 2 2 2 1 TrkA-N domain NAD_binding_7 PF13241.6 KXH60342.1 - 0.019 15.4 0.1 6.1 7.3 0.0 2.5 2 1 0 2 2 2 0 Putative NAD(P)-binding IlvN PF07991.12 KXH60342.1 - 0.074 12.6 0.0 1.3 8.5 0.0 2.2 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain FAD_oxidored PF12831.7 KXH60342.1 - 0.088 12.1 0.1 0.17 11.2 0.1 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase MCRA PF06100.11 KXH60342.1 - 0.12 11.1 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 MCRA family NAD_Gly3P_dh_N PF01210.23 KXH60342.1 - 0.21 11.6 0.0 2.4 8.1 0.1 2.1 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FGFR3_TM PF18123.1 KXH60342.1 - 0.29 10.7 0.7 0.58 9.7 0.7 1.5 1 0 0 1 1 1 0 Fibroblast growth factor receptor 3 transmembrane domain GAS2 PF02187.17 KXH60343.1 - 1.2e-06 28.5 0.1 2.8e-06 27.3 0.1 1.5 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain Malic_M PF03949.15 KXH60344.1 - 6.6e-93 310.7 0.0 9.1e-93 310.2 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 KXH60344.1 - 3.8e-71 238.6 0.0 6.6e-71 237.9 0.0 1.4 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain SKG6 PF08693.10 KXH60345.1 - 0.00023 20.5 5.4 0.00091 18.6 5.4 2.0 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4010 PF13194.6 KXH60345.1 - 0.0006 19.6 4.5 0.00098 18.9 4.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4010) Mucin PF01456.17 KXH60345.1 - 0.0044 17.0 19.2 0.0044 17.0 19.2 2.9 3 0 0 3 3 3 1 Mucin-like glycoprotein Podoplanin PF05808.11 KXH60345.1 - 0.015 15.4 8.1 0.035 14.2 8.1 1.6 1 0 0 1 1 1 0 Podoplanin FSA_C PF10479.9 KXH60345.1 - 1.8 6.6 12.5 3.4 5.7 12.5 1.4 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus 2-Hacid_dh_C PF02826.19 KXH60347.1 - 3.3e-52 176.4 0.0 5.6e-52 175.7 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KXH60347.1 - 1.7e-15 56.8 0.0 2.7e-15 56.2 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KXH60347.1 - 5.4e-05 23.4 0.0 0.00013 22.1 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AA_permease_2 PF13520.6 KXH60348.1 - 1.2e-51 176.0 36.9 1.7e-51 175.4 36.9 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXH60348.1 - 6e-30 104.3 27.6 6e-30 104.3 27.6 1.8 2 0 0 2 2 2 1 Amino acid permease DUF1754 PF08555.10 KXH60349.1 - 8.3e-12 45.8 22.5 2.3e-11 44.4 22.5 1.7 1 1 0 1 1 1 1 Eukaryotic family of unknown function (DUF1754) CDC27 PF09507.10 KXH60349.1 - 0.09 12.1 18.8 0.11 11.8 18.8 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 ORC2 PF04084.14 KXH60352.1 - 3.1e-118 394.5 0.0 3.5e-118 394.3 0.0 1.0 1 0 0 1 1 1 1 Origin recognition complex subunit 2 T2SSB PF16537.5 KXH60352.1 - 0.11 12.1 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 Type II secretion system protein B DUF806 PF05657.11 KXH60352.1 - 0.14 12.6 0.0 0.26 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF806) SHMT PF00464.19 KXH60400.1 - 2.4e-207 688.3 0.0 2.7e-207 688.1 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.21 KXH60400.1 - 0.0017 17.6 0.0 0.003 16.8 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KXH60400.1 - 0.055 12.0 0.0 0.091 11.3 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Asp PF00026.23 KXH60401.1 - 6.9e-110 367.4 0.1 9.9e-110 366.9 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KXH60401.1 - 3.1e-16 60.1 0.9 2.4e-09 37.7 0.6 2.3 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KXH60401.1 - 0.0001 22.9 0.0 1.1 10.0 0.0 3.3 2 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 KXH60401.1 - 0.00076 20.0 0.0 1.7 9.3 0.0 2.9 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 KXH60401.1 - 0.0033 17.2 0.0 0.019 14.7 0.0 2.2 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Ras PF00071.22 KXH60430.1 - 1e-51 174.7 0.0 1.2e-51 174.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXH60430.1 - 8.2e-20 71.2 0.0 1.2e-19 70.6 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXH60430.1 - 8.5e-11 41.6 0.0 1e-10 41.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KXH60430.1 - 1.6e-05 24.6 0.3 0.00015 21.4 0.2 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KXH60430.1 - 0.00031 20.8 0.0 0.00053 20.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KXH60430.1 - 0.0004 20.3 0.0 0.69 9.8 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase AAA_33 PF13671.6 KXH60430.1 - 0.0051 17.0 0.0 0.009 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KXH60430.1 - 0.044 14.1 0.2 0.63 10.3 0.1 2.6 2 1 0 2 2 2 0 AAA domain Scytalone_dh PF02982.14 KXH60430.1 - 0.045 13.6 0.0 0.17 11.7 0.0 1.8 2 0 0 2 2 2 0 Scytalone dehydratase AAA_16 PF13191.6 KXH60430.1 - 0.045 14.1 0.1 0.23 11.8 0.0 2.2 2 1 0 2 2 2 0 AAA ATPase domain NB-ARC PF00931.22 KXH60430.1 - 0.047 12.9 0.0 0.076 12.2 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Ras PF00071.22 KXH60454.1 - 1.1e-51 174.6 0.0 2e-51 173.8 0.0 1.4 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KXH60454.1 - 5.9e-18 65.2 0.0 8.2e-17 61.5 0.0 2.1 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXH60454.1 - 0.00052 19.5 0.0 0.0019 17.7 0.0 1.8 1 1 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KXH60454.1 - 0.018 15.0 0.0 5.2 6.9 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase Abhydrolase_4 PF08386.10 KXH60454.1 - 0.032 14.3 0.0 0.076 13.1 0.0 1.6 1 0 0 1 1 1 0 TAP-like protein FeoB_N PF02421.18 KXH60454.1 - 0.049 13.2 0.1 0.6 9.6 0.0 2.2 2 1 0 2 2 2 0 Ferrous iron transport protein B AAA_16 PF13191.6 KXH60454.1 - 0.062 13.7 0.0 0.084 13.2 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 KXH60454.1 - 0.14 11.8 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain Septin PF00735.18 KXH60454.1 - 0.19 10.9 0.0 0.4 9.9 0.0 1.5 2 0 0 2 2 2 0 Septin BDM PF10684.9 KXH60461.1 - 0.079 13.3 0.2 0.16 12.4 0.2 1.5 1 0 0 1 1 1 0 Putative biofilm-dependent modulation protein Hce2 PF14856.6 KXH60463.1 - 1.9e-19 69.8 0.0 2.6e-19 69.4 0.0 1.2 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor AAA_16 PF13191.6 KXH60464.1 - 6.8e-08 33.1 0.0 3.3e-07 30.8 0.0 2.2 2 0 0 2 2 1 1 AAA ATPase domain Abhydrolase_6 PF12697.7 KXH60464.1 - 0.00013 22.7 0.0 0.00098 19.8 0.0 2.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF676 PF05057.14 KXH60464.1 - 0.00034 20.2 0.3 0.00081 19.0 0.3 1.6 1 1 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 KXH60464.1 - 0.00042 20.1 0.1 0.00074 19.3 0.1 1.3 1 0 0 1 1 1 1 PGAP1-like protein RuvB_N PF05496.12 KXH60464.1 - 0.016 15.0 0.0 0.042 13.6 0.0 1.7 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 KXH60464.1 - 0.026 14.7 0.0 0.9 9.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 KXH60464.1 - 0.032 13.4 0.0 0.09 12.0 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain TniB PF05621.11 KXH60464.1 - 0.048 13.1 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein Sigma54_activat PF00158.26 KXH60464.1 - 0.18 11.5 0.0 0.35 10.6 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain ATPase PF06745.13 KXH60464.1 - 0.22 10.8 0.0 0.91 8.8 0.0 1.9 2 0 0 2 2 2 0 KaiC Syntaxin-6_N PF09177.11 KXH60464.1 - 0.28 11.7 0.1 0.28 11.7 0.1 2.2 2 0 0 2 2 2 0 Syntaxin 6, N-terminal FHA PF00498.26 KXH60465.1 - 4.9e-15 55.6 0.0 8.2e-15 54.9 0.0 1.4 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KXH60465.1 - 0.0062 16.8 0.0 0.095 13.0 0.0 2.2 1 1 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain VHS PF00790.19 KXH60466.1 - 9.2e-46 155.2 0.1 4e-45 153.1 0.0 2.1 3 0 0 3 3 3 1 VHS domain GAT PF03127.14 KXH60466.1 - 2.7e-18 66.0 0.2 2.7e-18 66.0 0.2 2.3 3 0 0 3 3 3 1 GAT domain Alpha_adaptinC2 PF02883.20 KXH60466.1 - 5.4e-17 62.1 0.0 1.7e-16 60.5 0.0 1.8 1 0 0 1 1 1 1 Adaptin C-terminal domain GGA_N-GAT PF18308.1 KXH60466.1 - 4.4e-08 32.6 0.0 1.3e-07 31.1 0.0 1.8 1 0 0 1 1 1 1 GGA N-GAT domain Ribo_biogen_C PF04034.13 KXH60467.1 - 2.1e-49 166.5 0.0 2.8e-49 166.1 0.0 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 KXH60467.1 - 5.8e-11 42.0 1.1 5.8e-11 42.0 1.1 1.7 2 0 0 2 2 2 1 Possible Fer4-like domain in RNase L inhibitor, RLI GTP_EFTU PF00009.27 KXH60468.1 - 1.9e-34 118.9 3.3 5.1e-33 114.2 3.3 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 KXH60468.1 - 9.4e-27 93.2 1.1 2.5e-26 91.9 0.8 1.9 2 0 0 2 2 2 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 KXH60468.1 - 3.2e-10 40.1 0.1 7.5e-10 38.9 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase IF2_N PF04760.15 KXH60468.1 - 2.7e-07 30.3 0.0 5.6e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region RsgA_GTPase PF03193.16 KXH60468.1 - 4.1e-07 30.1 0.3 3.7e-05 23.7 0.0 2.3 1 1 1 2 2 2 1 RsgA GTPase Arf PF00025.21 KXH60468.1 - 6.7e-05 22.4 0.0 0.00014 21.4 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family FeoB_N PF02421.18 KXH60468.1 - 0.00019 21.0 0.3 0.0006 19.4 0.1 2.0 2 1 0 2 2 2 1 Ferrous iron transport protein B SRPRB PF09439.10 KXH60468.1 - 0.00045 19.7 0.1 0.0011 18.4 0.1 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 KXH60468.1 - 0.0027 17.3 0.1 0.0046 16.6 0.1 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXH60468.1 - 0.0045 17.2 0.0 0.0081 16.4 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU_D4 PF14578.6 KXH60468.1 - 0.011 15.6 1.6 0.017 15.0 0.3 1.9 2 0 0 2 2 2 0 Elongation factor Tu domain 4 PduV-EutP PF10662.9 KXH60468.1 - 0.053 13.3 0.1 0.14 11.9 0.1 1.7 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 KXH60468.1 - 0.16 11.8 0.0 0.61 9.8 0.0 1.8 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein Dynamin_N PF00350.23 KXH60468.1 - 0.29 11.2 0.9 6.8 6.7 0.0 2.7 2 1 1 3 3 3 0 Dynamin family DUF4062 PF13271.6 KXH60469.1 - 0.038 14.4 0.0 0.087 13.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4062) PP28 PF10252.9 KXH60470.1 - 2.7e-26 91.8 18.1 2.7e-26 91.8 18.1 3.3 2 1 1 3 3 3 2 Casein kinase substrate phosphoprotein PP28 CoA_trans PF01144.23 KXH60472.1 - 2.2e-96 321.4 1.4 5.5e-59 199.2 0.0 2.0 2 0 0 2 2 2 2 Coenzyme A transferase Nrap_D4 PF17405.2 KXH60473.1 - 1e-59 201.5 0.0 2.9e-59 200.0 0.0 1.8 2 0 0 2 2 2 1 Nrap protein nucleotidyltransferase domain 4 Nrap_D5 PF17406.2 KXH60473.1 - 2.8e-57 193.0 0.7 2.6e-56 189.8 0.8 2.2 2 0 0 2 2 2 1 Nrap protein PAP/OAS1-like domain 5 Nrap_D2 PF17403.2 KXH60473.1 - 2.9e-52 176.5 0.3 7.7e-49 165.4 0.0 2.6 2 0 0 2 2 2 2 Nrap protein PAP/OAS-like domain Nrap_D3 PF17404.2 KXH60473.1 - 9.2e-47 159.1 0.1 2.1e-46 157.9 0.1 1.7 1 0 0 1 1 1 1 Nrap protein domain 3 Nrap PF03813.14 KXH60473.1 - 4.8e-46 156.6 0.1 8e-46 155.8 0.1 1.4 1 0 0 1 1 1 1 Nrap protein domain 1 Nrap_D6 PF17407.2 KXH60473.1 - 8.2e-36 123.2 0.0 1.8e-35 122.1 0.0 1.7 1 0 0 1 1 1 1 Nrap protein domain 6 Requiem_N PF14051.6 KXH60473.1 - 0.21 11.8 0.5 0.69 10.1 0.1 2.0 2 0 0 2 2 2 0 N-terminal domain of DPF2/REQ. DUF5011 PF16403.5 KXH60474.1 - 0.0072 16.4 0.0 0.063 13.4 0.0 2.8 2 0 0 2 2 2 1 Domain of unknown function (DUF5011) zf-C4H2 PF10146.9 KXH60474.1 - 0.08 13.2 0.0 0.17 12.2 0.0 1.5 1 0 0 1 1 1 0 Zinc finger-containing protein I-set PF07679.16 KXH60474.1 - 0.15 12.2 0.0 11 6.2 0.0 3.8 4 0 0 4 4 4 0 Immunoglobulin I-set domain Peptidase_C12 PF01088.21 KXH60475.1 - 7e-62 208.9 0.0 1e-61 208.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 F-box-like PF12937.7 KXH60476.1 - 1.4e-07 31.3 0.8 3.7e-07 29.9 0.8 1.8 1 0 0 1 1 1 1 F-box-like Transglut_core2 PF13369.6 KXH60476.1 - 1e-06 28.4 0.0 2.2e-06 27.3 0.0 1.6 1 1 0 1 1 1 1 Transglutaminase-like superfamily YccV-like PF08755.11 KXH60476.1 - 0.00013 22.4 0.6 0.0026 18.2 0.6 2.4 1 1 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like F-box PF00646.33 KXH60476.1 - 0.0011 18.8 0.3 0.0026 17.6 0.3 1.7 1 0 0 1 1 1 1 F-box domain DUF2868 PF11067.8 KXH60476.1 - 0.025 14.1 0.2 0.038 13.5 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) Cnn_1N PF07989.11 KXH60477.1 - 3.4e-26 91.2 3.3 3.4e-26 91.2 3.3 18.1 2 1 14 16 16 16 2 Centrosomin N-terminal motif 1 PACT_coil_coil PF10495.9 KXH60477.1 - 1.2e-25 89.8 1.7 1.2e-25 89.8 1.7 6.0 7 1 0 7 7 7 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein Spc7 PF08317.11 KXH60477.1 - 3.1e-05 23.0 223.9 0.0024 16.8 27.3 9.6 1 1 8 10 10 10 7 Spc7 kinetochore protein GAS PF13851.6 KXH60477.1 - 0.0017 17.7 25.9 0.0017 17.7 25.9 11.3 2 1 9 11 11 11 3 Growth-arrest specific micro-tubule binding DUF1664 PF07889.12 KXH60477.1 - 0.0018 18.3 7.4 0.0018 18.3 7.4 13.1 3 2 13 16 16 16 4 Protein of unknown function (DUF1664) MscS_porin PF12795.7 KXH60477.1 - 0.005 16.4 13.9 0.005 16.4 13.9 9.0 2 1 6 8 8 8 3 Mechanosensitive ion channel porin domain KASH_CCD PF14662.6 KXH60477.1 - 0.0056 16.5 17.6 0.0056 16.5 17.6 10.2 3 3 6 9 9 9 3 Coiled-coil region of CCDC155 or KASH Peptidase_C14 PF00656.22 KXH60478.1 - 1.9e-64 218.0 0.0 2.4e-64 217.7 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.6 KXH60478.1 - 0.17 11.8 0.0 0.64 10.0 0.0 1.9 2 0 0 2 2 2 0 Raptor N-terminal CASPase like domain Med25 PF11232.8 KXH60480.1 - 0.023 14.7 0.0 0.028 14.4 0.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 25 PTOV activation and synapsin 2 TLD PF07534.16 KXH60482.1 - 1.1e-24 87.2 0.0 5.2e-13 49.4 0.0 2.2 2 0 0 2 2 2 2 TLD Pkinase PF00069.25 KXH60483.1 - 5.7e-68 229.1 0.0 7.5e-68 228.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXH60483.1 - 5.8e-32 111.0 0.0 7.6e-32 110.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KXH60483.1 - 0.00034 20.0 0.3 0.00056 19.3 0.3 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KXH60483.1 - 0.0011 18.0 0.2 0.0018 17.3 0.2 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KXH60483.1 - 0.0078 15.6 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KXH60483.1 - 0.026 14.5 0.0 0.039 13.9 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KXH60483.1 - 0.058 12.4 0.0 0.089 11.8 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Gag_p6 PF08705.11 KXH60483.1 - 0.1 12.9 0.1 0.2 11.9 0.1 1.4 1 0 0 1 1 1 0 Gag protein p6 S_100 PF01023.19 KXH60483.1 - 0.13 12.0 0.2 0.38 10.5 0.2 1.8 1 0 0 1 1 1 0 S-100/ICaBP type calcium binding domain CbeA_antitoxin PF06154.11 KXH60498.1 - 0.11 13.1 0.0 0.57 10.8 0.0 2.0 2 0 0 2 2 2 0 CbeA_antitoxin, type IV, cytoskeleton bundling-enhancing factor A ADH_zinc_N PF00107.26 KXH60500.1 - 3.9e-08 33.3 0.0 1.1e-07 31.9 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KXH60500.1 - 0.00088 18.8 0.0 0.0014 18.1 0.0 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus FAD_binding_2 PF00890.24 KXH60500.1 - 0.0078 15.3 0.2 0.011 14.9 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KXH60500.1 - 0.016 13.9 0.0 0.021 13.5 0.0 1.1 1 0 0 1 1 1 0 HI0933-like protein AlaDh_PNT_C PF01262.21 KXH60500.1 - 0.026 13.8 0.2 0.037 13.3 0.2 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Amidohydro_3 PF07969.11 KXH60503.1 - 1.9e-05 24.3 5.5 0.00018 21.1 2.0 2.5 2 1 0 2 2 2 2 Amidohydrolase family IalB PF06776.12 KXH60503.1 - 0.0097 15.9 0.0 0.029 14.4 0.0 1.8 1 0 0 1 1 1 1 Invasion associated locus B (IalB) protein DUF2339 PF10101.9 KXH60504.1 - 0.0099 14.5 1.5 0.011 14.4 1.5 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2339) Fungal_trans PF04082.18 KXH60504.1 - 0.041 12.9 1.7 0.068 12.2 1.7 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain Peptidase_M28 PF04389.17 KXH60524.1 - 1.2e-39 136.0 0.0 2.5e-39 135.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KXH60524.1 - 9.1e-11 41.6 0.5 2.6e-10 40.2 0.2 1.9 2 0 0 2 2 2 1 PA domain Peptidase_M20 PF01546.28 KXH60524.1 - 0.00035 20.3 0.0 0.00064 19.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Ank_2 PF12796.7 KXH60525.1 - 1e-21 77.3 0.1 1.8e-07 31.7 0.0 3.7 2 2 2 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.30 KXH60525.1 - 1.2e-16 60.3 0.0 2.4e-05 24.6 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 KXH60525.1 - 3.4e-16 59.1 0.2 7e-06 26.2 0.0 4.0 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXH60525.1 - 3e-13 50.0 0.3 0.0012 19.4 0.0 4.3 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXH60525.1 - 3.3e-13 48.5 0.5 0.0012 19.2 0.0 5.4 6 0 0 6 6 6 2 Ankyrin repeat TPR_MalT PF17874.1 KXH60525.1 - 0.086 12.2 0.6 0.15 11.4 0.6 1.3 1 0 0 1 1 1 0 MalT-like TPR region Sugar_tr PF00083.24 KXH60526.1 - 1.6e-64 218.4 13.7 5.1e-63 213.5 13.7 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH60526.1 - 2e-08 33.6 39.0 1.9e-05 23.7 20.5 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4212 PF13937.6 KXH60526.1 - 0.058 13.8 6.2 0.058 13.8 0.2 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4212) MIP PF00230.20 KXH60527.1 - 2.7e-43 148.3 13.5 3.4e-43 148.0 13.5 1.1 1 0 0 1 1 1 1 Major intrinsic protein Aminotran_3 PF00202.21 KXH60528.1 - 0.00073 18.3 0.0 0.0011 17.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-III 7tm_3 PF00003.22 KXH60528.1 - 0.0073 16.1 1.9 0.023 14.4 1.8 1.7 1 1 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Methyltransf_23 PF13489.6 KXH60529.1 - 8.2e-19 68.0 0.0 2.5e-18 66.4 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH60529.1 - 2.3e-13 50.7 0.0 1e-12 48.6 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH60529.1 - 6.4e-11 42.8 0.0 1.4e-10 41.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH60529.1 - 1.7e-09 38.3 0.0 1.9e-08 35.0 0.0 2.7 3 1 0 3 3 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH60529.1 - 2.5e-08 33.8 0.0 7.3e-07 29.1 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXH60529.1 - 5.8e-05 22.5 0.0 0.00078 18.8 0.0 2.4 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 KXH60529.1 - 0.0003 20.1 0.0 0.0017 17.7 0.0 1.9 1 1 0 1 1 1 1 O-methyltransferase domain MTS PF05175.14 KXH60529.1 - 0.0014 18.2 0.0 0.0097 15.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_4 PF02390.17 KXH60529.1 - 0.0083 15.6 0.0 0.051 13.0 0.0 2.2 3 0 0 3 3 3 1 Putative methyltransferase CMAS PF02353.20 KXH60529.1 - 0.066 12.5 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_16 PF10294.9 KXH60529.1 - 0.069 12.9 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase PrmA PF06325.13 KXH60529.1 - 0.072 12.5 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Hamartin PF04388.12 KXH60529.1 - 2.6 6.6 3.4 3.4 6.2 3.4 1.1 1 0 0 1 1 1 0 Hamartin protein Tyrosinase PF00264.20 KXH60530.1 - 3.7e-54 184.3 0.4 4.9e-54 184.0 0.4 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase Peroxidase_2 PF01328.17 KXH60531.1 - 3.9e-45 154.7 0.0 5.2e-45 154.3 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 Peptidase_M28 PF04389.17 KXH60532.1 - 3.8e-37 127.9 0.0 5.4e-37 127.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KXH60532.1 - 1.8e-14 53.5 1.0 4.2e-14 52.3 1.0 1.7 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 KXH60532.1 - 4.5e-06 26.5 0.1 9e-06 25.5 0.1 1.6 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Ank_2 PF12796.7 KXH60535.1 - 2.9e-40 136.7 21.4 8.1e-06 26.3 0.0 14.9 12 3 2 14 14 14 12 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXH60535.1 - 1.5e-17 63.7 17.9 0.46 11.1 0.1 15.7 15 4 3 18 18 18 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXH60535.1 - 2.4e-14 52.0 23.7 0.0031 17.9 0.0 18.1 23 1 1 24 24 24 2 Ankyrin repeat Ank_5 PF13857.6 KXH60535.1 - 5e-13 49.0 9.3 2.5e-06 27.6 0.0 11.1 14 0 0 14 14 14 2 Ankyrin repeats (many copies) Ank PF00023.30 KXH60535.1 - 5.8e-09 36.0 38.2 0.00044 20.6 0.0 16.2 18 1 1 19 19 19 2 Ankyrin repeat DUF2624 PF11116.8 KXH60535.1 - 0.17 12.8 0.2 65 4.5 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2624) ADH_zinc_N PF00107.26 KXH60536.1 - 4.9e-30 104.2 0.2 8.3e-30 103.4 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXH60536.1 - 3e-22 80.1 0.0 5.1e-22 79.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXH60536.1 - 1.3e-09 37.9 0.0 6.5e-09 35.7 0.0 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 KXH60536.1 - 0.00071 19.5 0.0 0.0017 18.3 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase adh_short PF00106.25 KXH60536.1 - 0.012 15.1 1.7 0.029 13.8 1.7 1.6 1 1 0 1 1 1 0 short chain dehydrogenase GDP_Man_Dehyd PF16363.5 KXH60537.1 - 6.3e-49 167.2 0.0 1.1e-48 166.4 0.0 1.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KXH60537.1 - 1.3e-46 159.0 0.0 1.9e-46 158.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXH60537.1 - 4.9e-19 68.4 0.1 3.1e-18 65.8 0.0 1.9 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KXH60537.1 - 8.8e-16 57.9 0.0 1.1e-13 51.0 0.0 2.2 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KXH60537.1 - 2.8e-12 46.3 0.0 4.1e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 KXH60537.1 - 1.2e-10 41.2 0.0 1.9e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXH60537.1 - 6.1e-09 36.0 0.0 1.1e-08 35.3 0.0 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.12 KXH60537.1 - 3.4e-07 29.7 0.0 1.6e-06 27.5 0.0 1.9 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 KXH60537.1 - 8.1e-05 22.6 0.0 0.00013 21.9 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding adh_short_C2 PF13561.6 KXH60537.1 - 0.0015 18.1 0.0 0.0026 17.3 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase UDPG_MGDP_dh_N PF03721.14 KXH60537.1 - 0.013 15.1 0.0 0.022 14.4 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NmrA PF05368.13 KXH60537.1 - 0.016 14.8 0.0 0.036 13.6 0.0 1.6 2 0 0 2 2 2 0 NmrA-like family Sad1_UNC PF07738.13 KXH60538.1 - 1.1e-08 35.2 0.0 5.3e-08 32.9 0.0 2.0 1 1 0 1 1 1 1 Sad1 / UNC-like C-terminal PP2C_C PF07830.13 KXH60538.1 - 0.086 13.3 0.9 0.86 10.1 0.2 2.6 2 0 0 2 2 2 0 Protein serine/threonine phosphatase 2C, C-terminal domain DEAD PF00270.29 KXH60539.1 - 7.1e-47 159.4 0.0 1.8e-46 158.1 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.6 KXH60539.1 - 1.3e-22 79.8 0.0 3.1e-22 78.6 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.31 KXH60539.1 - 1.1e-21 77.3 0.0 1.6e-20 73.5 0.0 2.8 1 1 1 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXH60539.1 - 1.3e-07 31.8 0.0 3.4e-07 30.4 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Glyoxalase PF00903.25 KXH60540.1 - 1.7e-09 37.9 0.0 2.3e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily YecM PF06185.12 KXH60540.1 - 0.015 15.0 0.0 0.019 14.6 0.0 1.2 1 0 0 1 1 1 0 YecM protein adh_short PF00106.25 KXH60541.1 - 3e-26 92.1 0.0 1.1e-19 70.7 0.0 2.1 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXH60541.1 - 4.1e-12 46.2 0.0 4.8e-10 39.4 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH60541.1 - 2.2e-06 27.7 0.0 3.3e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXH60541.1 - 4.9e-05 22.9 0.0 6.4e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KXH60541.1 - 0.0041 16.3 0.0 0.0062 15.7 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein ERG4_ERG24 PF01222.17 KXH60542.1 - 3.3e-90 302.9 8.3 3.9e-90 302.7 8.3 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 KXH60542.1 - 3.7e-05 23.4 1.7 3.7e-05 23.4 0.3 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) ICMT PF04140.14 KXH60542.1 - 0.00064 20.1 0.0 0.0018 18.7 0.0 1.7 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family p450 PF00067.22 KXH60543.1 - 7.7e-36 123.8 0.0 5.3e-25 88.1 0.0 2.3 2 1 0 2 2 2 2 Cytochrome P450 MBOAT_2 PF13813.6 KXH60544.1 - 5.2e-12 45.9 4.9 1.6e-11 44.3 3.7 2.5 2 1 0 2 2 2 1 Membrane bound O-acyl transferase family HisKA_7TM PF16927.5 KXH60544.1 - 4.5 7.2 14.8 0.033 14.2 3.4 2.7 3 0 0 3 3 3 0 N-terminal 7TM region of histidine kinase p450 PF00067.22 KXH60545.1 - 2e-86 290.6 0.0 8.4e-37 127.0 0.0 4.1 4 0 0 4 4 4 4 Cytochrome P450 PRY PF13765.6 KXH60545.1 - 0.13 11.9 0.5 0.34 10.6 0.1 1.9 2 0 0 2 2 2 0 SPRY-associated domain p450 PF00067.22 KXH60546.1 - 1.2e-59 202.4 0.0 1.5e-59 202.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Beta-lactamase PF00144.24 KXH60547.1 - 1.4e-38 133.0 0.0 1.8e-38 132.6 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Beta-lactamase2 PF13354.6 KXH60547.1 - 0.00091 18.9 0.0 0.002 17.7 0.0 1.6 2 0 0 2 2 2 1 Beta-lactamase enzyme family Adeno_PV PF03910.13 KXH60548.1 - 2.3 6.9 8.8 2.6 6.7 8.8 1.1 1 0 0 1 1 1 0 Adenovirus minor core protein PV DUF2967 PF11179.8 KXH60548.1 - 3.4 5.7 13.6 3.7 5.5 13.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) Glyco_hydro_28 PF00295.17 KXH60550.1 - 7.8e-12 44.9 2.7 1.6e-11 43.8 2.7 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.6 KXH60550.1 - 0.022 14.6 19.7 0.083 12.7 16.0 2.6 2 1 1 3 3 3 0 Right handed beta helix region DUF5123 PF17161.4 KXH60550.1 - 0.12 13.4 1.3 0.26 12.4 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5123) GLEYA PF10528.9 KXH60551.1 - 1.6e-46 156.6 19.1 1.3e-28 99.2 6.0 3.5 2 1 1 3 3 3 2 GLEYA domain PA14 PF07691.12 KXH60551.1 - 3e-22 79.0 0.3 1.3e-10 41.2 0.5 2.4 2 0 0 2 2 2 2 PA14 domain C1q PF00386.21 KXH60551.1 - 0.59 10.3 8.5 4.2 7.6 1.0 2.4 2 0 0 2 2 2 0 C1q domain Romo1 PF10247.9 KXH60551.1 - 0.73 10.2 8.7 53 4.3 0.1 5.5 6 0 0 6 6 6 0 Reactive mitochondrial oxygen species modulator 1 Alginate_lyase PF05426.12 KXH60552.1 - 4.2e-20 72.4 0.2 8.1e-20 71.5 0.2 1.4 1 1 0 1 1 1 1 Alginate lyase Reticulon PF02453.17 KXH60553.1 - 1.3e-17 64.2 0.0 1.9e-17 63.7 0.0 1.3 1 0 0 1 1 1 1 Reticulon FUSC_2 PF13515.6 KXH60553.1 - 0.014 15.5 1.1 0.46 10.6 0.1 2.2 2 0 0 2 2 2 0 Fusaric acid resistance protein-like DLIC PF05783.11 KXH60553.1 - 1.4 7.6 5.9 2 7.2 5.9 1.1 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Glyco_hydro_16 PF00722.21 KXH60554.1 - 0.00032 20.2 0.0 0.0007 19.1 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 OB_NTP_bind PF07717.16 KXH60556.1 - 9e-23 80.5 0.0 1.8e-22 79.5 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 KXH60556.1 - 5e-22 78.2 0.1 5e-22 78.2 0.1 2.7 3 0 0 3 3 3 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KXH60556.1 - 6.9e-13 48.9 0.0 1.7e-12 47.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.23 KXH60556.1 - 4.6e-11 42.9 1.1 9.1e-11 42.0 1.1 1.5 1 0 0 1 1 1 1 S1 RNA binding domain AAA_22 PF13401.6 KXH60556.1 - 3.2e-08 33.9 0.0 7.4e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 KXH60556.1 - 5.8e-06 26.2 0.1 1.4e-05 25.0 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_30 PF13604.6 KXH60556.1 - 0.00012 21.9 0.3 0.00032 20.5 0.3 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KXH60556.1 - 0.00043 20.6 0.3 0.00085 19.7 0.3 1.4 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 KXH60556.1 - 0.0023 17.0 0.0 0.0052 15.9 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein DUF2075 PF09848.9 KXH60556.1 - 0.056 12.7 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 KXH60556.1 - 0.063 12.7 0.0 0.15 11.5 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_14 PF13173.6 KXH60556.1 - 0.077 13.0 0.3 0.66 10.0 0.3 2.2 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KXH60556.1 - 0.11 13.0 0.2 1.6 9.2 0.1 2.5 1 1 0 2 2 2 0 ABC transporter IPK PF03770.16 KXH60557.1 - 7.8e-52 176.0 0.0 1e-51 175.7 0.0 1.1 1 0 0 1 1 1 1 Inositol polyphosphate kinase Arb1 PF09692.10 KXH60558.1 - 1.2e-128 429.7 0.0 1.4e-128 429.5 0.0 1.0 1 0 0 1 1 1 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 Pmp3 PF01679.17 KXH60559.1 - 4.7e-20 71.5 9.1 5.9e-20 71.2 9.1 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator CLP1_P PF16575.5 KXH60560.1 - 3.2e-35 121.7 0.0 5.7e-35 120.8 0.0 1.4 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop CLP1_N PF16573.5 KXH60560.1 - 1.2e-26 92.7 0.0 2.1e-26 92.0 0.0 1.4 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor Clp1 PF06807.14 KXH60560.1 - 3.4e-26 92.0 0.0 7.1e-26 90.9 0.0 1.6 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 ATP_bind_1 PF03029.17 KXH60560.1 - 0.0017 18.2 0.1 0.0036 17.1 0.1 1.5 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_33 PF13671.6 KXH60560.1 - 0.0022 18.2 0.0 0.005 17.0 0.0 1.5 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 KXH60560.1 - 0.0055 16.8 0.1 0.013 15.6 0.1 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_24 PF13479.6 KXH60560.1 - 0.0093 15.7 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain FeoB_N PF02421.18 KXH60560.1 - 0.043 13.3 0.0 0.15 11.6 0.0 1.9 2 0 0 2 2 2 0 Ferrous iron transport protein B KTI12 PF08433.10 KXH60560.1 - 0.052 13.0 0.0 0.69 9.3 0.0 2.1 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_16 PF13191.6 KXH60560.1 - 0.059 13.8 0.0 0.099 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain IstB_IS21 PF01695.17 KXH60560.1 - 0.082 12.6 0.0 0.39 10.4 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_35 PF14516.6 KXH60560.1 - 0.094 11.5 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_28 PF13521.6 KXH60560.1 - 0.11 12.7 0.1 0.22 11.8 0.1 1.5 1 0 0 1 1 1 0 AAA domain CbiA PF01656.23 KXH60560.1 - 0.15 12.1 0.0 0.27 11.3 0.0 1.3 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Transferase PF02458.15 KXH60561.1 - 3.7e-13 48.9 0.0 4.2e-09 35.6 0.0 2.2 2 0 0 2 2 2 2 Transferase family Methyltransf_23 PF13489.6 KXH60562.1 - 1.7e-24 86.5 0.0 2.5e-24 86.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH60562.1 - 2.8e-11 44.0 0.0 7.2e-11 42.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH60562.1 - 2.1e-08 34.8 0.0 8.5e-08 32.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH60562.1 - 7.8e-08 32.3 0.0 3.9e-07 30.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH60562.1 - 9.8e-08 32.5 0.0 1.9e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXH60562.1 - 0.0055 16.3 0.0 0.019 14.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase small domain FtsJ PF01728.19 KXH60562.1 - 0.0068 16.5 0.0 0.0099 16.0 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Ubie_methyltran PF01209.18 KXH60562.1 - 0.068 12.5 0.0 7.1 5.9 0.0 2.4 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.9 KXH60562.1 - 0.14 11.9 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Gamma-thionin PF00304.20 KXH60564.1 - 4.4 7.7 28.2 0.86 9.9 3.8 3.5 3 0 0 3 3 3 0 Gamma-thionin family Colipase PF01114.18 KXH60564.1 - 9.3 6.0 29.6 0.33 10.6 4.9 3.5 3 0 0 3 3 3 0 Colipase, N-terminal domain Acyl_transf_3 PF01757.22 KXH60565.1 - 2.9e-26 92.3 25.4 7.9e-22 77.8 21.8 2.9 2 1 0 2 2 2 2 Acyltransferase family ThrE PF06738.12 KXH60566.1 - 7.6e-64 215.4 27.8 6.4e-61 205.8 4.6 2.9 2 1 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 KXH60566.1 - 1.8e-12 47.5 35.2 1.7e-11 44.4 14.8 2.5 2 0 0 2 2 2 2 Threonine/Serine exporter, ThrE DUF2651 PF10852.8 KXH60566.1 - 0.038 14.6 1.4 0.12 13.1 1.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2651) Synaptobrevin PF00957.21 KXH60567.1 - 0.13 12.1 0.2 0.35 10.7 0.2 1.7 1 0 0 1 1 1 0 Synaptobrevin Pkinase PF00069.25 KXH60568.1 - 2e-19 70.0 0.0 3.4e-19 69.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXH60568.1 - 1.4e-13 50.8 0.0 2.1e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF2540 PF10802.8 KXH60568.1 - 0.16 12.1 0.1 11 6.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2540) HET PF06985.11 KXH60569.1 - 1.5e-24 87.0 0.1 3.1e-24 86.0 0.1 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Pkinase PF00069.25 KXH60569.1 - 3e-23 82.5 0.0 4.7e-23 81.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXH60569.1 - 4.9e-14 52.2 0.0 7.9e-14 51.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PROCT PF08084.11 KXH60569.1 - 0.12 12.3 1.0 0.35 10.8 1.0 1.7 1 1 1 2 2 2 0 PROCT (NUC072) domain Ank_2 PF12796.7 KXH60570.1 - 1.2e-17 64.3 0.0 1.3e-05 25.7 0.0 5.8 4 2 1 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXH60570.1 - 4.4e-13 49.5 0.4 0.14 12.8 0.0 7.3 6 1 1 7 7 7 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXH60570.1 - 2.1e-12 47.0 0.9 0.092 13.1 0.0 6.2 4 1 2 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXH60570.1 - 1.8e-10 40.1 4.4 0.026 15.0 0.0 8.7 10 0 0 10 10 10 2 Ankyrin repeat Ank PF00023.30 KXH60570.1 - 2e-09 37.5 5.6 0.65 10.5 0.0 7.2 7 0 0 7 7 7 3 Ankyrin repeat PAS_9 PF13426.7 KXH60571.1 - 5.1e-13 49.2 0.0 8.2e-12 45.3 0.0 2.5 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.10 KXH60571.1 - 1.4e-05 25.2 0.0 3.9e-05 23.9 0.0 1.8 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 KXH60571.1 - 6.9e-05 22.8 0.0 0.0003 20.8 0.0 2.1 2 0 0 2 2 2 1 PAS fold RGS PF00615.19 KXH60571.1 - 0.0042 17.4 0.1 0.074 13.3 0.1 2.5 1 1 0 1 1 1 1 Regulator of G protein signaling domain Aa_trans PF01490.18 KXH60572.1 - 4.2e-44 150.9 34.6 4.8e-44 150.7 34.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein CAAD PF14159.6 KXH60572.1 - 0.0044 16.8 1.2 0.033 14.0 0.4 3.0 2 0 0 2 2 2 1 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase tRNA_SAD PF07973.14 KXH60573.1 - 4.2e-07 29.9 1.1 4.2e-07 29.9 1.1 1.9 2 0 0 2 2 2 1 Threonyl and Alanyl tRNA synthetase second additional domain tRNA-synt_2c PF01411.19 KXH60573.1 - 0.016 13.7 0.0 0.027 13.0 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class II (A) PH_8 PF15409.6 KXH60573.1 - 0.065 13.5 0.2 0.15 12.3 0.2 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain DUF724 PF05266.14 KXH60573.1 - 0.081 12.7 0.1 0.13 12.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) D-ser_dehydrat PF14031.6 KXH60574.1 - 2.2e-22 79.5 0.1 5.1e-22 78.3 0.1 1.7 1 0 0 1 1 1 1 Putative serine dehydratase domain Ala_racemase_N PF01168.20 KXH60574.1 - 3.1e-10 40.1 0.2 4.5e-10 39.6 0.2 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain HET PF06985.11 KXH60575.1 - 1.4e-27 96.9 0.0 3.7e-27 95.5 0.0 1.8 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Glyco_hydro_3_C PF01915.22 KXH60576.1 - 1e-45 156.2 0.0 1.6e-45 155.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KXH60576.1 - 5.4e-37 127.8 0.0 9e-37 127.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KXH60576.1 - 1e-21 76.8 0.1 1.9e-21 76.0 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Caleosin PF05042.13 KXH60577.1 - 1.8e-77 259.0 0.4 2.4e-77 258.7 0.4 1.1 1 0 0 1 1 1 1 Caleosin related protein EF-hand_6 PF13405.6 KXH60577.1 - 0.19 11.7 1.8 38 4.6 0.1 3.4 3 0 0 3 3 3 0 EF-hand domain Helo_like_N PF17111.5 KXH60579.1 - 0.01 15.2 0.2 0.016 14.6 0.2 1.3 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins DHR10 PF18595.1 KXH60579.1 - 0.012 15.7 0.4 0.017 15.2 0.4 1.2 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain DUF948 PF06103.11 KXH60579.1 - 0.052 13.8 0.9 0.83 10.0 1.1 1.9 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Laminin_II PF06009.12 KXH60579.1 - 0.058 13.4 0.4 0.13 12.2 0.4 1.5 1 1 1 2 2 2 0 Laminin Domain II BLOC1_2 PF10046.9 KXH60579.1 - 0.098 13.0 0.6 0.19 12.1 0.6 1.5 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DivIC PF04977.15 KXH60579.1 - 0.16 11.8 0.1 0.51 10.1 0.0 1.8 2 0 0 2 2 2 0 Septum formation initiator Sec20 PF03908.13 KXH60579.1 - 0.18 11.7 1.5 3.5 7.6 0.3 2.1 1 1 1 2 2 2 0 Sec20 Fzo_mitofusin PF04799.13 KXH60579.1 - 0.21 11.1 1.5 0.78 9.3 1.6 1.7 1 1 1 2 2 2 0 fzo-like conserved region FAD_binding_3 PF01494.19 KXH60580.1 - 4.7e-70 236.6 0.0 6.1e-70 236.2 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 KXH60580.1 - 0.0014 18.0 0.0 0.0029 16.9 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXH60580.1 - 0.0016 17.6 0.1 0.0034 16.5 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KXH60580.1 - 0.002 16.9 0.0 0.004 15.9 0.0 1.4 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.6 KXH60580.1 - 0.0025 18.0 0.1 0.0076 16.5 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXH60580.1 - 0.0053 16.0 0.0 0.019 14.2 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KXH60580.1 - 0.0059 15.7 0.0 0.013 14.6 0.0 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 KXH60580.1 - 0.0094 15.6 0.0 0.035 13.7 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 KXH60580.1 - 0.011 14.9 0.1 0.019 14.2 0.1 1.2 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.22 KXH60580.1 - 0.02 14.0 0.0 0.03 13.4 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_oxidored PF12831.7 KXH60580.1 - 0.062 12.6 0.1 0.097 12.0 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Fungal_trans PF04082.18 KXH60581.1 - 8.5e-22 77.4 0.5 1.4e-21 76.7 0.5 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain FAA_hydrolase PF01557.18 KXH60582.1 - 6.9e-69 231.8 0.0 8.3e-69 231.6 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family DUF2437 PF10370.9 KXH60582.1 - 0.0035 18.2 0.0 0.012 16.5 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF2437) FAD_binding_3 PF01494.19 KXH60583.1 - 1.2e-23 84.0 0.0 1.7e-23 83.4 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KXH60583.1 - 2.7e-08 33.8 3.4 0.007 16.0 0.0 2.7 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KXH60583.1 - 8.2e-07 28.4 2.9 1.8e-06 27.3 2.9 1.6 1 0 0 1 1 1 1 FAD binding domain Glyoxalase PF00903.25 KXH60583.1 - 2.2e-06 27.9 0.1 0.00065 19.9 0.2 2.6 1 1 1 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Pyr_redox_2 PF07992.14 KXH60583.1 - 6.2e-06 25.7 2.7 9.6e-05 21.7 2.7 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXH60583.1 - 8.4e-06 25.9 2.8 1.2e-05 25.5 1.3 2.1 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KXH60583.1 - 8.6e-05 21.9 1.0 0.00021 20.6 0.2 1.9 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 KXH60583.1 - 0.00016 20.6 1.3 0.00027 19.8 0.9 1.5 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 KXH60583.1 - 0.0015 18.0 3.4 0.0021 17.5 2.8 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KXH60583.1 - 0.0016 18.9 0.2 0.039 14.5 0.2 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXH60583.1 - 0.017 14.4 1.2 0.028 13.7 1.2 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KXH60583.1 - 0.074 11.9 0.6 0.31 9.8 0.2 1.9 1 1 1 2 2 2 0 Tryptophan halogenase FMO-like PF00743.19 KXH60583.1 - 0.081 11.3 0.5 0.12 10.8 0.5 1.2 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like GIDA PF01134.22 KXH60583.1 - 0.14 11.2 3.1 0.24 10.4 3.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Zn_clus PF00172.18 KXH60584.1 - 4.3e-07 30.0 12.3 7.9e-07 29.1 12.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_6 PF12697.7 KXH60585.1 - 3e-08 34.5 0.3 5.5e-07 30.4 0.1 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF1100 PF06500.11 KXH60585.1 - 3.2e-07 29.5 0.0 4.6e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Peptidase_S9 PF00326.21 KXH60585.1 - 4e-07 29.7 0.0 1.3e-06 28.1 0.0 1.8 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KXH60585.1 - 3e-05 23.4 0.0 6e-05 22.4 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KXH60585.1 - 0.00028 20.6 0.1 0.001 18.8 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold AXE1 PF05448.12 KXH60585.1 - 0.00058 18.6 0.0 0.0017 17.1 0.0 1.7 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) DUF2920 PF11144.8 KXH60585.1 - 0.028 13.6 0.0 0.045 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) Abhydrolase_3 PF07859.13 KXH60585.1 - 0.054 13.3 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 alpha/beta hydrolase fold BAAT_C PF08840.11 KXH60585.1 - 0.096 12.6 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal UPF0227 PF05728.12 KXH60585.1 - 0.098 12.6 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Sulfotransfer_4 PF17784.1 KXH60586.1 - 8.3e-60 202.3 0.0 1.3e-59 201.6 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KXH60586.1 - 0.00095 19.6 0.0 0.0018 18.7 0.0 1.5 1 0 0 1 1 1 1 Sulfotransferase family SurE PF01975.17 KXH60587.1 - 1.3e-29 103.4 0.1 1.8e-29 102.9 0.1 1.2 1 0 0 1 1 1 1 Survival protein SurE Glyoxalase PF00903.25 KXH60588.1 - 6.1e-09 36.1 5.8 1e-05 25.7 2.2 2.8 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily TPR_2 PF07719.17 KXH60588.1 - 0.028 14.5 0.1 0.37 11.0 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_3 PF07720.12 KXH60588.1 - 0.073 13.1 1.4 0.7 10.0 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 KXH60588.1 - 0.1 12.4 0.5 0.98 9.4 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Acid_PPase PF12689.7 KXH60589.1 - 1.1e-65 220.7 0.0 1.2e-65 220.4 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase CRAL_TRIO PF00650.20 KXH60590.1 - 3.8e-26 91.7 0.0 5.4e-26 91.2 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KXH60590.1 - 1.8e-09 37.6 0.0 4.1e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain F-box-like PF12937.7 KXH60592.1 - 3.8e-05 23.5 0.7 0.0001 22.1 0.7 1.8 1 0 0 1 1 1 1 F-box-like Ank_2 PF12796.7 KXH60592.1 - 0.086 13.4 0.1 3.3 8.4 0.1 3.0 2 2 1 3 3 3 0 Ankyrin repeats (3 copies) CFEM PF05730.11 KXH60594.1 - 0.062 13.4 2.0 0.85 9.8 2.0 2.0 1 1 0 1 1 1 0 CFEM domain R3H-assoc PF13902.6 KXH60595.1 - 8.3e-25 87.7 1.8 1.7e-24 86.7 1.8 1.5 1 0 0 1 1 1 1 R3H-associated N-terminal domain R3H PF01424.22 KXH60595.1 - 0.00077 19.4 0.0 0.0028 17.6 0.0 1.9 1 0 0 1 1 1 1 R3H domain CCD48 PF15799.5 KXH60595.1 - 0.017 13.5 1.4 0.03 12.6 1.4 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 48 PQ-loop PF04193.14 KXH60596.1 - 7.2e-21 73.7 17.0 6.8e-12 45.0 0.8 3.4 3 1 0 3 3 3 2 PQ loop repeat ANAPC4_WD40 PF12894.7 KXH60597.1 - 0.026 14.8 0.0 2.3 8.6 0.0 3.1 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain peroxidase PF00141.23 KXH60598.1 - 3e-29 102.4 0.0 4.3e-29 101.8 0.0 1.2 1 0 0 1 1 1 1 Peroxidase ISG65-75 PF11727.8 KXH60598.1 - 0.13 11.5 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 Invariant surface glycoprotein CUE PF02845.16 KXH60599.1 - 0.019 14.7 0.2 3.3 7.5 0.0 3.0 3 0 0 3 3 3 0 CUE domain DJ-1_PfpI PF01965.24 KXH60600.1 - 1.9e-13 50.5 0.0 2.4e-13 50.2 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family Peptidase_S8 PF00082.22 KXH60601.1 - 2e-41 142.2 0.4 3.4e-41 141.4 0.4 1.4 1 0 0 1 1 1 1 Subtilase family IU_nuc_hydro PF01156.19 KXH60601.1 - 2.1e-18 66.9 0.0 4.2e-18 66.0 0.0 1.4 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase fn3_5 PF06280.12 KXH60601.1 - 7.2e-16 58.9 0.1 1.3e-15 58.1 0.1 1.4 1 0 0 1 1 1 1 Fn3-like domain p450 PF00067.22 KXH60601.1 - 1.1e-13 50.8 0.0 1.4e-06 27.4 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 Cadherin_C PF01049.17 KXH60601.1 - 0.14 12.5 0.1 0.3 11.4 0.1 1.5 1 0 0 1 1 1 0 Cadherin cytoplasmic region Amidase PF01425.21 KXH60602.1 - 4.2e-92 309.5 0.0 5e-92 309.2 0.0 1.1 1 0 0 1 1 1 1 Amidase Fungal_trans PF04082.18 KXH60603.1 - 1.6e-10 40.5 0.0 3e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.25 KXH60603.1 - 0.037 13.5 0.0 0.086 12.3 0.0 1.6 1 0 0 1 1 1 0 short chain dehydrogenase FAD_binding_4 PF01565.23 KXH60604.1 - 4.1e-21 75.2 1.4 4.1e-21 75.2 1.4 1.8 2 0 0 2 2 2 1 FAD binding domain SLATT_1 PF18181.1 KXH60606.1 - 0.048 13.6 0.9 0.14 12.1 0.9 1.8 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 1 Fungal_trans PF04082.18 KXH60607.1 - 6.5e-07 28.6 0.0 1.6e-06 27.4 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KXH60607.1 - 0.059 13.9 2.2 0.12 12.8 2.2 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXH60607.1 - 0.15 13.0 1.6 0.34 11.9 1.6 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger Glyco_hydro_18 PF00704.28 KXH60608.1 - 2.5e-52 178.6 1.6 3.5e-52 178.1 1.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 KXH60608.1 - 1.8e-10 41.1 38.3 5.4e-07 30.0 12.7 3.0 2 0 0 2 2 2 2 Chitin recognition protein Chitin_bind_1 PF00187.19 KXH60609.1 - 7.7e-26 90.3 172.1 2.5e-05 24.6 19.6 8.0 6 2 1 7 7 7 6 Chitin recognition protein ADH_zinc_N PF00107.26 KXH60610.1 - 3.9e-23 81.8 0.4 7.6e-23 80.9 0.4 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXH60610.1 - 1.2e-13 52.2 0.0 2.1e-13 51.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXH60610.1 - 1.4e-10 41.0 0.0 2.6e-09 36.9 0.0 2.3 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 KXH60610.1 - 0.12 12.3 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase FAD_binding_4 PF01565.23 KXH60611.1 - 9.9e-23 80.4 0.5 1.8e-22 79.6 0.5 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KXH60611.1 - 0.00014 21.9 0.3 0.00028 20.9 0.3 1.5 1 0 0 1 1 1 1 Berberine and berberine like 2OG-FeII_Oxy PF03171.20 KXH60613.1 - 1.7e-10 41.3 0.3 7.9e-09 35.9 0.3 2.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 KXH60613.1 - 2.2e-05 25.2 0.1 6.3e-05 23.7 0.0 1.8 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal CDO_I PF05995.12 KXH60614.1 - 1.3e-38 132.0 0.1 1.9e-38 131.5 0.1 1.2 1 0 0 1 1 1 1 Cysteine dioxygenase type I PCO_ADO PF07847.12 KXH60614.1 - 0.002 17.6 0.0 0.0025 17.3 0.0 1.3 1 0 0 1 1 1 1 PCO_ADO MFS_1 PF07690.16 KXH60615.1 - 5.5e-20 71.6 40.1 5.5e-20 71.6 40.1 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 KXH60615.1 - 0.0001 21.3 22.0 0.0066 15.3 7.1 3.0 1 1 2 3 3 3 3 MFS_1 like family DUF1449 PF07290.11 KXH60615.1 - 0.26 10.9 3.4 0.61 9.7 3.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1449) MFS_1 PF07690.16 KXH60617.1 - 1.3e-08 34.2 34.8 1.3e-08 34.2 34.8 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily F-box-like PF12937.7 KXH60619.1 - 4.3e-05 23.3 0.2 0.00012 21.9 0.2 1.8 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 KXH60619.1 - 0.026 14.4 0.0 0.054 13.4 0.0 1.5 1 0 0 1 1 1 0 F-box Ank_2 PF12796.7 KXH60620.1 - 2.7e-11 43.9 6.8 2.3e-05 24.9 0.2 3.9 2 2 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXH60620.1 - 1.5e-10 41.1 3.7 0.0022 18.3 0.1 4.7 4 2 1 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXH60620.1 - 1.7e-09 37.1 5.5 0.0091 16.4 0.1 5.2 6 0 0 6 6 6 2 Ankyrin repeat Ank_4 PF13637.6 KXH60620.1 - 4e-09 36.8 1.6 0.0055 17.3 0.1 4.5 2 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 KXH60620.1 - 2.2e-07 31.0 13.2 0.0089 16.4 0.1 6.0 6 1 0 6 6 6 2 Ankyrin repeat F-box-like PF12937.7 KXH60620.1 - 0.0012 18.7 0.0 0.0059 16.5 0.0 2.2 2 1 0 2 2 2 1 F-box-like DUF4267 PF14087.6 KXH60622.1 - 3.2e-21 75.5 2.0 4.2e-21 75.1 2.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) DUF456 PF04306.13 KXH60622.1 - 0.17 12.2 5.2 0.034 14.4 1.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF456) MFS_1 PF07690.16 KXH60623.1 - 4.4e-26 91.6 33.2 7.8e-26 90.8 33.1 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH60623.1 - 5.7e-10 38.6 27.8 7.1e-09 35.0 27.6 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 KXH60623.1 - 1.2e-06 27.3 5.6 1.7e-06 26.8 5.6 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) SUIM_assoc PF16619.5 KXH60624.1 - 1.6 8.9 15.1 0.3 11.2 8.8 2.6 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 MFS_1 PF07690.16 KXH60625.1 - 1.2e-33 116.5 48.4 1.2e-32 113.2 48.6 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF1345 PF07077.11 KXH60625.1 - 0.007 16.1 3.2 0.018 14.7 2.5 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1345) Gemini_mov PF01708.16 KXH60625.1 - 2 8.2 5.0 40 4.1 0.0 3.1 3 1 0 3 3 3 0 Geminivirus putative movement protein Phospholamban PF04272.14 KXH60625.1 - 8.3 6.0 6.0 2.9 7.4 0.1 2.8 2 0 0 2 2 2 0 Phospholamban p450 PF00067.22 KXH60627.1 - 2.7e-75 253.9 0.0 3.1e-75 253.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Fer4_2 PF12797.7 KXH60628.1 - 0.15 12.2 0.6 0.15 12.2 0.6 2.8 3 0 0 3 3 3 0 4Fe-4S binding domain SnoaL PF07366.12 KXH60629.1 - 0.0098 15.7 0.1 0.07 12.9 0.0 2.2 1 1 0 2 2 2 1 SnoaL-like polyketide cyclase COesterase PF00135.28 KXH60630.1 - 5e-80 269.8 0.0 6.6e-80 269.4 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXH60630.1 - 0.0046 16.8 0.4 0.051 13.4 0.1 2.5 2 1 0 2 2 2 1 alpha/beta hydrolase fold ubiquitin PF00240.23 KXH60631.1 - 4.9e-16 58.3 0.0 8.4e-16 57.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KXH60631.1 - 5.8e-10 38.9 0.0 1.1e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 KXH60631.1 - 0.032 14.3 0.1 0.14 12.3 0.0 2.0 1 1 1 2 2 2 0 Ubiquitin-like domain Ubiquitin_2 PF14560.6 KXH60631.1 - 0.12 12.9 0.0 0.27 11.7 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-like domain ZZ PF00569.17 KXH60635.1 - 7.3e-11 41.7 6.8 1.4e-10 40.8 6.8 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.31 KXH60635.1 - 4.6e-09 36.3 0.0 2.9e-08 33.8 0.0 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain SWIRM PF04433.17 KXH60635.1 - 1.5e-07 31.6 0.0 4.2e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 SWIRM domain GalP_UDP_tr_C PF02744.17 KXH60636.1 - 4.4e-60 202.2 0.5 8.7e-60 201.2 0.2 1.6 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, C-terminal domain GalP_UDP_transf PF01087.22 KXH60636.1 - 1e-50 172.7 1.6 1.5e-41 142.8 0.1 3.1 2 1 1 3 3 3 2 Galactose-1-phosphate uridyl transferase, N-terminal domain HIT PF01230.23 KXH60636.1 - 2.2e-07 31.5 0.2 3.8e-05 24.4 0.0 2.6 2 1 0 2 2 2 2 HIT domain Erg28 PF03694.13 KXH60637.1 - 2.4e-41 140.5 0.8 3e-41 140.2 0.8 1.1 1 0 0 1 1 1 1 Erg28 like protein adh_short PF00106.25 KXH60638.1 - 2.6e-40 138.0 0.0 3.5e-40 137.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXH60638.1 - 3.5e-26 92.2 0.0 5.2e-26 91.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH60638.1 - 3.9e-07 30.2 0.1 1e-06 28.8 0.1 1.6 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KXH60638.1 - 0.00097 18.3 0.0 0.0013 17.9 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 KXH60638.1 - 0.011 15.7 0.1 0.02 14.8 0.1 1.4 1 1 0 1 1 1 0 NAD(P)H-binding Nucleoporin_N PF08801.11 KXH60639.1 - 2.9e-97 326.2 0.0 4.1e-97 325.7 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.14 KXH60639.1 - 3.9e-52 177.8 5.8 1.7e-51 175.7 1.4 2.0 1 1 0 2 2 2 2 Non-repetitive/WGA-negative nucleoporin C-terminal Phasin_2 PF09361.10 KXH60639.1 - 0.0012 19.0 0.6 0.0046 17.2 0.6 2.0 1 0 0 1 1 1 1 Phasin protein Ubie_methyltran PF01209.18 KXH60640.1 - 3.8e-12 46.0 0.0 8.6e-12 44.9 0.0 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 KXH60640.1 - 1.6e-11 44.7 0.0 3.2e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH60640.1 - 4.5e-11 43.3 0.0 8.6e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH60640.1 - 4.6e-07 29.8 0.0 8e-07 29.0 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXH60640.1 - 1e-05 25.4 0.0 1.9e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH60640.1 - 2.9e-05 24.8 0.0 7.1e-05 23.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain DUF1697 PF08002.11 KXH60640.1 - 0.028 14.9 0.0 0.057 13.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1697) Amino_oxidase PF01593.24 KXH60641.1 - 6.3e-61 207.0 0.0 9.7e-60 203.1 0.0 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KXH60641.1 - 5.6e-09 36.1 0.0 1.6e-08 34.7 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXH60641.1 - 0.0013 18.1 0.0 0.027 13.7 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXH60641.1 - 0.0059 15.9 0.1 0.035 13.3 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXH60641.1 - 0.041 14.4 0.1 0.74 10.4 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KXH60641.1 - 0.049 12.9 0.3 0.087 12.1 0.3 1.4 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.22 KXH60641.1 - 0.086 11.9 0.0 0.18 10.8 0.0 1.5 1 0 0 1 1 1 0 Glucose inhibited division protein A Shikimate_DH PF01488.20 KXH60641.1 - 0.15 12.1 0.1 0.28 11.3 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.17 KXH60641.1 - 0.17 11.1 0.1 0.3 10.3 0.1 1.3 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.6 KXH60641.1 - 0.27 11.2 2.1 2.1 8.3 0.1 2.8 2 1 0 2 2 2 0 FAD-NAD(P)-binding Clr5 PF14420.6 KXH60642.1 - 0.069 13.4 0.0 0.2 11.9 0.0 1.9 1 0 0 1 1 1 0 Clr5 domain TPD52 PF04201.15 KXH60642.1 - 0.12 11.9 0.0 0.32 10.6 0.0 1.6 2 0 0 2 2 2 0 Tumour protein D52 family PPE PF00823.19 KXH60642.1 - 0.15 12.1 0.0 0.26 11.4 0.0 1.3 1 0 0 1 1 1 0 PPE family Clr5 PF14420.6 KXH60643.1 - 3.1e-14 52.9 2.4 4.9e-14 52.3 2.4 1.3 1 0 0 1 1 1 1 Clr5 domain DUF2206 PF09971.9 KXH60644.1 - 0.0002 20.3 1.8 0.00021 20.2 1.8 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2206) Glucan_synthase PF02364.15 KXH60644.1 - 0.055 11.6 0.2 0.062 11.5 0.2 1.0 1 0 0 1 1 1 0 1,3-beta-glucan synthase component Lung_7-TM_R PF06814.13 KXH60644.1 - 0.065 12.5 3.8 0.076 12.2 3.8 1.1 1 0 0 1 1 1 0 Lung seven transmembrane receptor p450 PF00067.22 KXH60646.1 - 3.8e-69 233.6 0.0 6e-69 233.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 DUF2781 PF10914.8 KXH60646.1 - 3.6e-36 124.8 12.0 3.6e-36 124.8 12.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2781) MFS_1 PF07690.16 KXH60647.1 - 1.5e-46 159.0 25.1 1.5e-46 159.0 25.1 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH60647.1 - 5e-09 35.5 11.1 5e-09 35.5 11.1 2.0 1 1 1 2 2 2 1 Sugar (and other) transporter MFS_3 PF05977.13 KXH60647.1 - 0.0031 16.0 2.2 0.0041 15.6 2.2 1.2 1 0 0 1 1 1 1 Transmembrane secretion effector CDC50 PF03381.15 KXH60648.1 - 6.9e-52 176.7 1.5 8.4e-52 176.4 1.5 1.0 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family PhoLip_ATPase_C PF16212.5 KXH60649.1 - 1.2e-57 195.5 6.5 1.2e-57 195.5 6.5 1.8 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KXH60649.1 - 2e-23 81.8 0.5 2e-23 81.8 0.5 1.8 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal E1-E2_ATPase PF00122.20 KXH60649.1 - 5.3e-11 42.4 0.0 1.2e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase PF13246.6 KXH60649.1 - 1.1e-10 41.5 0.0 1.1e-09 38.2 0.0 2.4 3 0 0 3 3 3 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KXH60649.1 - 5.3e-09 36.7 0.0 0.0003 21.1 0.0 3.3 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KXH60649.1 - 0.014 15.2 0.2 0.035 13.8 0.0 1.7 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase PBP PF01161.20 KXH60650.1 - 3.4e-11 43.6 0.0 5.4e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein NAD_binding_10 PF13460.6 KXH60651.1 - 8.9e-08 32.2 0.0 1.1e-07 32.0 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding Fungal_trans_2 PF11951.8 KXH60652.1 - 8.8e-46 156.4 0.5 1.3e-45 155.9 0.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Peptidase_S8 PF00082.22 KXH60653.1 - 3.3e-39 134.9 0.3 5.2e-39 134.3 0.3 1.3 1 0 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 KXH60653.1 - 4e-21 75.8 0.1 1.1e-20 74.5 0.0 1.8 2 0 0 2 2 2 1 Fn3-like domain ADH_zinc_N PF00107.26 KXH60654.1 - 2.3e-22 79.4 0.0 4.9e-22 78.3 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXH60654.1 - 7.1e-21 74.1 3.1 7.1e-21 74.1 3.1 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KXH60654.1 - 8.1e-08 33.4 0.0 1.7e-07 32.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KXH60654.1 - 6.9e-07 28.8 0.1 1.1e-06 28.1 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 KXH60654.1 - 0.00018 20.9 0.1 0.00031 20.1 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KXH60654.1 - 0.054 13.6 0.0 0.12 12.4 0.0 1.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Tannase PF07519.11 KXH60655.1 - 1.4e-89 301.2 0.1 1.6e-89 301.0 0.1 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_S9 PF00326.21 KXH60655.1 - 2.1e-08 33.9 0.1 0.0065 16.0 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KXH60655.1 - 9.4e-05 21.8 0.0 0.0018 17.6 0.0 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Asn_synthase PF00733.21 KXH60656.1 - 9.7e-66 222.8 0.0 1.3e-65 222.5 0.0 1.1 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.6 KXH60656.1 - 6.8e-35 119.7 0.0 1.3e-34 118.8 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 KXH60656.1 - 1.1e-33 116.3 0.0 2.1e-33 115.4 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 KXH60656.1 - 7.3e-06 25.6 0.0 1.4e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.17 KXH60656.1 - 0.049 12.8 0.0 0.083 12.0 0.0 1.3 1 0 0 1 1 1 0 NAD synthase PBP_GOBP PF01395.22 KXH60657.1 - 0.089 13.0 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 PBP/GOBP family NPP1 PF05630.11 KXH60658.1 - 1.9e-30 106.4 0.0 2.5e-30 106.1 0.0 1.1 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) GFO_IDH_MocA PF01408.22 KXH60659.1 - 6.8e-20 72.1 0.1 1.5e-19 71.0 0.0 1.5 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KXH60659.1 - 1.2e-07 31.8 0.0 2.5e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain AAA_33 PF13671.6 KXH60659.1 - 0.00043 20.5 0.0 0.00085 19.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain NAD_binding_3 PF03447.16 KXH60659.1 - 0.0057 17.3 0.0 0.012 16.2 0.0 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.24 KXH60659.1 - 0.057 13.8 0.0 0.1 13.0 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DUF1593 PF07632.11 KXH60660.1 - 3.7e-86 288.7 0.1 4.8e-86 288.4 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1593) REJ PF02010.15 KXH60660.1 - 0.039 12.8 0.0 0.056 12.2 0.0 1.2 1 0 0 1 1 1 0 REJ domain Peptidase_S15 PF02129.18 KXH60662.1 - 1.9e-35 122.7 2.5 3.1e-32 112.2 1.2 2.1 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 KXH60663.1 - 2.6e-11 43.9 0.0 2e-10 41.0 0.0 1.9 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Peptidase_M14 PF00246.24 KXH60664.1 - 5.8e-82 275.8 0.1 6.9e-82 275.5 0.1 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase CorA PF01544.18 KXH60665.1 - 7.6e-42 143.6 0.2 1.1e-41 143.1 0.2 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Transferase PF02458.15 KXH60666.1 - 1.1e-24 86.9 0.0 2.3e-17 62.8 0.0 2.2 2 0 0 2 2 2 2 Transferase family p450 PF00067.22 KXH60667.1 - 2.8e-61 207.7 0.0 3.3e-61 207.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SPC12 PF06645.13 KXH60667.1 - 0.12 12.5 0.7 1.4 9.0 0.1 2.4 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) Cyt-b5 PF00173.28 KXH60668.1 - 1.3e-20 73.3 0.5 1.7e-20 72.9 0.5 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain ketoacyl-synt PF00109.26 KXH60669.1 - 1e-74 251.3 0.6 2.1e-74 250.3 0.0 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KXH60669.1 - 3.3e-59 199.8 0.0 6.9e-59 198.8 0.0 1.6 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 KXH60669.1 - 2.5e-53 181.3 0.0 4e-53 180.6 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 KXH60669.1 - 2.8e-48 165.1 0.1 6.4e-48 163.9 0.1 1.6 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KXH60669.1 - 9.5e-34 115.9 0.0 2.6e-33 114.5 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KXH60669.1 - 1.1e-18 67.7 0.0 2.8e-18 66.4 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 KXH60669.1 - 2.2e-08 33.8 0.1 2e-06 27.4 0.0 2.6 2 0 0 2 2 2 1 short chain dehydrogenase Thiolase_N PF00108.23 KXH60669.1 - 1.4e-05 24.6 0.9 2.2e-05 23.9 0.0 1.7 2 0 0 2 2 2 1 Thiolase, N-terminal domain adh_short_C2 PF13561.6 KXH60669.1 - 0.00094 18.8 0.0 0.0025 17.4 0.0 1.7 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ADH_zinc_N PF00107.26 KXH60669.1 - 0.0027 17.7 0.0 0.0084 16.1 0.0 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_11 PF08241.12 KXH60669.1 - 0.025 15.2 0.0 0.097 13.3 0.0 2.1 1 0 0 1 1 1 0 Methyltransferase domain ACP_syn_III PF08545.10 KXH60669.1 - 0.055 13.3 0.1 0.2 11.5 0.1 2.0 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Methyltransf_23 PF13489.6 KXH60669.1 - 0.092 12.6 0.0 0.24 11.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain FSH1 PF03959.13 KXH60670.1 - 6.5e-27 94.6 0.3 5.6e-26 91.5 0.3 2.3 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 KXH60670.1 - 0.032 14.0 0.2 0.35 10.6 0.1 2.1 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase MFS_1 PF07690.16 KXH60671.1 - 1.2e-40 139.5 39.4 1.2e-40 139.5 39.4 1.7 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KXH60671.1 - 1.5e-09 36.9 24.4 2.5e-09 36.1 24.4 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) ketoacyl-synt PF00109.26 KXH60672.1 - 1.7e-70 237.5 0.0 3e-70 236.7 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.6 KXH60672.1 - 6.6e-59 199.6 0.0 1.1e-58 198.8 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 KXH60672.1 - 1.7e-55 187.7 0.1 8.1e-55 185.5 0.0 2.4 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.21 KXH60672.1 - 1.2e-47 163.0 0.0 2.1e-47 162.2 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KXH60672.1 - 1.6e-40 137.8 0.1 5.4e-40 136.1 0.1 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N_2 PF13602.6 KXH60672.1 - 1.5e-20 74.6 0.0 1.2e-19 71.7 0.0 2.4 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.12 KXH60672.1 - 3.2e-18 66.3 0.0 1.7e-17 64.0 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 KXH60672.1 - 4e-16 59.4 0.0 1.2e-15 58.0 0.0 1.9 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N PF00107.26 KXH60672.1 - 6.1e-15 55.3 0.1 2.1e-14 53.6 0.1 2.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.6 KXH60672.1 - 6.3e-10 39.1 0.0 1.2e-09 38.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH60672.1 - 9.3e-10 39.1 0.0 3.9e-09 37.1 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 KXH60672.1 - 1.7e-09 37.4 0.0 3e-07 30.1 0.0 2.8 3 0 0 3 3 3 1 short chain dehydrogenase Methyltransf_11 PF08241.12 KXH60672.1 - 1.1e-07 32.4 0.0 4.6e-07 30.4 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH60672.1 - 3e-06 27.1 0.0 1.3e-05 25.0 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain adh_short_C2 PF13561.6 KXH60672.1 - 9.9e-05 22.0 0.0 0.001 18.7 0.0 2.3 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Ubie_methyltran PF01209.18 KXH60672.1 - 0.00012 21.5 0.1 0.00024 20.5 0.1 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family ADH_N PF08240.12 KXH60672.1 - 0.00092 19.1 0.0 0.0019 18.1 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.25 KXH60672.1 - 0.0025 18.1 0.0 0.0063 16.8 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_16 PF10294.9 KXH60672.1 - 0.01 15.6 0.0 0.022 14.5 0.0 1.5 1 0 0 1 1 1 0 Lysine methyltransferase Thiolase_N PF00108.23 KXH60672.1 - 0.079 12.3 0.3 0.44 9.9 0.0 2.3 2 0 0 2 2 2 0 Thiolase, N-terminal domain Spermine_synth PF01564.17 KXH60672.1 - 0.2 11.1 1.0 0.44 9.9 0.1 1.9 2 0 0 2 2 2 0 Spermine/spermidine synthase domain p450 PF00067.22 KXH60674.1 - 2.6e-58 197.9 0.0 4e-46 157.7 0.0 2.0 1 1 0 2 2 2 2 Cytochrome P450 HU-CCDC81_bac_2 PF18175.1 KXH60674.1 - 0.072 13.0 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 CCDC81-like prokaryotic HU domain 2 TauD PF02668.16 KXH60675.1 - 3.6e-61 207.3 0.5 4.5e-61 207.0 0.5 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.16 KXH60676.1 - 7.3e-33 113.9 11.8 7.3e-33 113.9 11.8 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 KXH60676.1 - 0.001 18.4 0.6 0.0019 17.6 0.6 1.3 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB Pox_E6 PF04656.12 KXH60676.1 - 0.15 10.5 0.1 1.7 7.0 0.0 2.0 2 0 0 2 2 2 0 Pox virus E6 protein A_deaminase PF00962.22 KXH60677.1 - 1.8e-38 132.7 0.0 2.5e-38 132.2 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase Amidohydro_1 PF01979.20 KXH60677.1 - 0.18 11.1 0.1 0.42 9.9 0.0 1.6 2 1 0 2 2 2 0 Amidohydrolase family MFS_1 PF07690.16 KXH60678.1 - 1.4e-30 106.5 31.2 1.9e-30 106.0 31.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 KXH60678.1 - 1.1e-06 28.2 4.4 1.1e-06 28.2 4.4 2.2 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB SfLAP PF11139.8 KXH60678.1 - 0.04 13.3 0.1 0.04 13.3 0.1 2.5 2 0 0 2 2 2 0 Sap, sulfolipid-1-addressing protein DUF2196 PF09962.9 KXH60679.1 - 3.9e-22 78.0 4.4 7.1e-22 77.2 4.4 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2196) TOBE_2 PF08402.10 KXH60679.1 - 0.028 14.6 0.4 0.059 13.5 0.4 1.6 1 0 0 1 1 1 0 TOBE domain Zn-C2H2_12 PF18112.1 KXH60679.1 - 4.7 7.8 6.3 26 5.4 6.3 2.0 1 1 0 1 1 1 0 Autophagy receptor zinc finger-C2H2 domain Exo5 PF09810.9 KXH60682.1 - 3.1e-139 464.6 0.0 3.8e-139 464.3 0.0 1.1 1 0 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease PDDEXK_1 PF12705.7 KXH60682.1 - 0.049 13.5 0.3 2.7 7.8 0.0 2.6 2 1 0 2 2 2 0 PD-(D/E)XK nuclease superfamily Mac PF12464.8 KXH60683.1 - 1.3e-13 50.9 0.1 2.5e-13 50.0 0.1 1.5 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep_2 PF14602.6 KXH60683.1 - 0.0055 16.4 1.5 0.2 11.4 0.1 2.4 2 0 0 2 2 2 1 Hexapeptide repeat of succinyl-transferase Hexapep PF00132.24 KXH60683.1 - 0.02 14.6 0.1 0.075 12.8 0.0 1.9 2 0 0 2 2 2 0 Bacterial transferase hexapeptide (six repeats) ACT_6 PF13740.6 KXH60683.1 - 0.091 12.8 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 ACT domain DUF349 PF03993.12 KXH60684.1 - 7.4 7.0 0.0 7.4 7.0 0.0 3.2 3 0 0 3 3 3 0 Domain of Unknown Function (DUF349) Tap-RNA_bind PF09162.10 KXH60685.1 - 0.1 12.5 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Tap, RNA-binding DUF4455 PF14643.6 KXH60692.1 - 0.0023 16.7 2.4 0.0027 16.4 2.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4455) SF-assemblin PF06705.11 KXH60692.1 - 0.014 14.8 3.5 0.021 14.2 3.5 1.2 1 0 0 1 1 1 0 SF-assemblin/beta giardin REC114-like PF15165.6 KXH60692.1 - 0.04 13.7 1.2 0.05 13.4 1.2 1.2 1 0 0 1 1 1 0 Meiotic recombination protein REC114-like TLE_N PF03920.15 KXH60692.1 - 0.041 14.0 3.7 0.098 12.7 3.2 2.0 1 1 1 2 2 2 0 Groucho/TLE N-terminal Q-rich domain Collagen_mid PF15984.5 KXH60692.1 - 0.11 12.2 0.6 0.21 11.3 0.6 1.5 1 1 0 1 1 1 0 Bacterial collagen, middle region Tweety PF04906.13 KXH60692.1 - 0.3 9.7 2.6 0.39 9.3 2.6 1.1 1 0 0 1 1 1 0 Tweety OmpH PF03938.14 KXH60692.1 - 1.6 9.0 9.0 2.5 8.4 9.0 1.5 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) DBINO PF13892.6 KXH60692.1 - 2 8.8 9.5 0.22 11.9 3.2 2.0 1 1 1 2 2 2 0 DNA-binding domain DUF3294 PF07957.11 KXH60693.1 - 0.082 12.6 0.0 0.09 12.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3294) MFS_1 PF07690.16 KXH60694.1 - 2e-24 86.2 45.4 3.3e-24 85.5 45.4 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily Osmo_MPGsynth PF09488.10 KXH60695.1 - 7.5e-153 508.8 0.0 9e-153 508.6 0.0 1.1 1 0 0 1 1 1 1 Mannosyl-3-phosphoglycerate synthase (osmo_MPGsynth) CW_binding_2 PF04122.12 KXH60695.1 - 0.073 13.7 0.1 0.2 12.3 0.1 1.8 1 0 0 1 1 1 0 Putative cell wall binding repeat 2 Corona_nucleoca PF00937.18 KXH60695.1 - 0.29 10.1 7.4 0.47 9.4 7.4 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Apt1 PF10351.9 KXH60695.1 - 0.43 9.4 4.7 0.75 8.6 4.7 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain TruB_C_2 PF16198.5 KXH60696.1 - 0.027 14.6 0.0 0.13 12.4 0.0 2.3 1 0 0 1 1 1 0 tRNA pseudouridylate synthase B C-terminal domain RGS PF00615.19 KXH60719.1 - 5.1e-38 130.0 0.7 1.9e-37 128.1 0.0 2.4 3 0 0 3 3 3 1 Regulator of G protein signaling domain DEP PF00610.21 KXH60719.1 - 1.3e-25 89.3 0.6 1.7e-21 76.0 0.0 3.7 4 0 0 4 4 4 3 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Fungal_trans PF04082.18 KXH60747.1 - 0.00025 20.2 0.1 0.0005 19.2 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF5514 PF17633.2 KXH60747.1 - 0.2 11.9 0.0 0.32 11.2 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5514) Peptidase_S15 PF02129.18 KXH60748.1 - 4.5e-38 131.4 3.9 4.9e-32 111.6 0.3 2.4 2 0 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 KXH60748.1 - 1.2e-33 117.0 0.0 3.5e-33 115.4 0.0 1.8 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain EthD PF07110.11 KXH60748.1 - 2.3e-07 31.9 0.0 3.1e-06 28.2 0.0 2.5 2 0 0 2 2 2 1 EthD domain Peptidase_S9 PF00326.21 KXH60748.1 - 0.00098 18.7 0.3 0.0073 15.8 0.3 2.2 1 1 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KXH60748.1 - 0.0091 15.3 0.0 1.8 7.8 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 LRR_4 PF12799.7 KXH60749.1 - 1e-09 38.5 17.3 0.00078 19.8 0.4 5.7 6 1 0 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXH60749.1 - 3e-08 33.3 17.1 0.0061 16.3 3.1 4.9 3 1 2 5 5 5 4 Leucine rich repeat LRRNT_2 PF08263.12 KXH60749.1 - 0.00014 22.1 0.2 0.00029 21.1 0.2 1.6 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain LRR_1 PF00560.33 KXH60749.1 - 0.0016 18.7 13.0 1e+02 4.1 0.4 7.9 8 1 0 8 8 8 0 Leucine Rich Repeat LRR_6 PF13516.6 KXH60749.1 - 0.3 11.2 9.6 23 5.3 0.0 5.5 6 0 0 6 6 6 0 Leucine Rich repeat Glyco_hydro_2_N PF02837.18 KXH60750.1 - 3.7e-17 62.7 0.0 1.3e-16 60.9 0.0 2.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.17 KXH60750.1 - 2e-09 37.0 0.1 6.9e-09 35.2 0.1 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.21 KXH60750.1 - 6.4e-09 36.5 0.0 1.5e-08 35.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.6 KXH60750.1 - 0.066 13.8 2.3 0.1 13.2 0.5 2.1 2 0 0 2 2 2 0 Beta-galactosidase jelly roll domain Aa_trans PF01490.18 KXH60751.1 - 2.1e-44 151.9 27.5 2.3e-44 151.7 27.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KXH60751.1 - 3.4e-05 23.1 10.5 3.4e-05 23.1 10.5 2.1 1 1 1 2 2 2 1 Tryptophan/tyrosine permease family DUF433 PF04255.14 KXH60751.1 - 0.039 13.8 0.1 0.11 12.4 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF433) Bap31 PF05529.12 KXH60751.1 - 0.96 9.3 4.7 0.47 10.3 1.1 2.3 2 0 0 2 2 2 0 Bap31/Bap29 transmembrane region Kelch_5 PF13854.6 KXH60752.1 - 4.4e-16 58.5 7.0 1.7e-06 27.9 0.1 4.9 4 0 0 4 4 4 4 Kelch motif Kelch_6 PF13964.6 KXH60752.1 - 2.9e-11 43.2 4.5 0.0038 17.5 0.0 5.2 5 0 0 5 5 5 3 Kelch motif Kelch_4 PF13418.6 KXH60752.1 - 4.7e-10 39.3 4.6 0.18 11.8 0.1 5.9 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_3 PF13415.6 KXH60752.1 - 2.2e-08 34.2 12.1 0.006 16.8 0.0 6.2 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_1 PF01344.25 KXH60752.1 - 5.7e-06 25.8 7.9 0.0082 15.7 0.1 5.0 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.15 KXH60752.1 - 0.0013 18.6 5.9 0.047 13.7 0.1 4.4 5 0 0 5 5 5 1 Kelch motif Pyr_redox_2 PF07992.14 KXH60753.1 - 5e-14 52.2 0.0 1.7e-08 34.1 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXH60753.1 - 6.3e-05 22.4 0.0 0.012 14.9 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KXH60753.1 - 0.00019 20.7 0.5 0.097 11.7 0.0 2.3 1 1 0 2 2 2 2 Glucose inhibited division protein A K_oxygenase PF13434.6 KXH60753.1 - 0.00031 20.0 0.0 0.13 11.4 0.0 2.2 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KXH60753.1 - 0.00032 20.9 0.1 0.00091 19.4 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KXH60753.1 - 0.00036 19.4 0.1 0.0021 16.8 0.0 1.9 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 KXH60753.1 - 0.0008 18.7 0.0 0.012 14.9 0.1 2.1 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 KXH60753.1 - 0.0014 17.8 2.9 0.0052 15.9 0.1 2.5 2 1 0 3 3 3 1 FAD binding domain NAD_binding_9 PF13454.6 KXH60753.1 - 0.0029 17.6 0.5 1.5 8.8 0.1 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KXH60753.1 - 0.004 16.3 0.0 0.17 10.9 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.24 KXH60753.1 - 0.0046 16.6 1.4 0.08 12.5 0.3 2.2 1 1 1 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KXH60753.1 - 0.0089 15.3 0.0 0.017 14.4 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KXH60753.1 - 0.023 14.1 0.2 0.047 13.0 0.2 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase DIOX_N PF14226.6 KXH60754.1 - 6.6e-16 59.1 0.1 1.2e-15 58.3 0.1 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KXH60754.1 - 3.2e-15 56.5 0.0 6.1e-15 55.5 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily OxoDH_E1alpha_N PF12573.8 KXH60754.1 - 0.33 10.7 3.9 1.9 8.3 0.0 3.0 3 0 0 3 3 3 0 2-oxoisovalerate dehydrogenase E1 alpha subunit N terminal MFS_1 PF07690.16 KXH60755.1 - 1.2e-09 37.6 22.8 9.2e-08 31.4 11.0 2.8 2 1 1 3 3 3 2 Major Facilitator Superfamily Fig1 PF12351.8 KXH60755.1 - 2.5 8.0 7.8 39 4.1 4.8 2.9 3 0 0 3 3 3 0 Ca2+ regulator and membrane fusion protein Fig1 CUE PF02845.16 KXH60756.1 - 1.1e-07 31.4 0.0 1.8e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 CUE domain ADH_zinc_N_2 PF13602.6 KXH60758.1 - 4.4e-29 102.2 0.2 7.9e-29 101.4 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KXH60758.1 - 2e-15 56.9 1.4 3.5e-15 56.1 0.5 2.0 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXH60758.1 - 1.9e-07 30.9 0.4 3e-05 23.8 0.0 2.9 1 1 1 3 3 3 2 Alcohol dehydrogenase GroES-like domain Transferase PF02458.15 KXH60759.1 - 3.1e-22 78.8 0.0 2.4e-15 56.1 0.0 2.7 2 1 0 2 2 2 2 Transferase family Condensation PF00668.20 KXH60759.1 - 0.1 11.2 0.0 0.16 10.6 0.0 1.2 1 0 0 1 1 1 0 Condensation domain Secapin PF17521.2 KXH60760.1 - 0.011 15.5 1.1 0.011 15.5 1.1 19.5 13 8 11 24 24 24 0 Honey bee peptides PAN_4 PF14295.6 KXH60761.1 - 0.092 12.7 9.0 0.095 12.6 2.2 3.1 2 0 0 2 2 2 0 PAN domain DUF966 PF06136.13 KXH60761.1 - 5.2 6.7 16.0 7.3 6.2 16.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) TPR_7 PF13176.6 KXH60762.1 - 0.00052 19.8 0.1 0.79 9.9 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 KXH60762.1 - 0.0046 17.4 5.5 0.48 11.0 0.1 3.8 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KXH60762.1 - 0.17 12.8 3.3 60 4.8 0.0 4.5 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 KXH60762.1 - 1.9 8.8 4.6 2 8.8 0.4 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat Ferric_reduct PF01794.19 KXH60763.1 - 1.3e-14 54.4 9.5 2.5e-14 53.5 9.5 1.5 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KXH60763.1 - 1.4e-13 51.2 0.1 2.2e-11 44.1 0.0 2.4 2 1 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KXH60763.1 - 1.8e-09 37.6 0.0 3.7e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 KXH60763.1 - 0.034 14.8 0.0 3.6 8.3 0.0 2.4 1 1 0 2 2 2 0 Oxidoreductase NAD-binding domain MerC PF03203.14 KXH60763.1 - 5.9 7.4 9.5 50 4.4 9.3 2.2 1 1 1 2 2 2 0 MerC mercury resistance protein MFS_1 PF07690.16 KXH60764.1 - 2.4e-23 82.7 30.7 9.1e-17 61.0 12.0 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH60764.1 - 1e-13 51.0 11.4 1e-13 51.0 11.4 1.5 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH60765.1 - 7e-41 140.3 27.1 1e-40 139.8 27.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily HupE_UreJ PF04955.12 KXH60765.1 - 0.94 8.9 7.4 0.24 10.8 3.5 2.1 2 0 0 2 2 2 0 HupE / UreJ protein Fungal_trans PF04082.18 KXH60766.1 - 4.3e-16 58.7 0.0 7.1e-16 58.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain FAA_hydrolase PF01557.18 KXH60768.1 - 1.5e-64 217.7 0.0 1.8e-64 217.4 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family DnaJ PF00226.31 KXH60769.1 - 2.2e-05 24.5 0.0 0.38 10.9 0.0 2.7 2 0 0 2 2 2 2 DnaJ domain Dehydrin PF00257.19 KXH60769.1 - 0.23 12.0 2.5 0.18 12.3 0.6 1.7 2 0 0 2 2 2 0 Dehydrin DUF883 PF05957.13 KXH60769.1 - 0.65 10.6 5.7 0.14 12.7 2.0 1.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Fungal_trans PF04082.18 KXH60770.1 - 2.6e-14 52.9 2.0 2.6e-14 52.9 2.0 2.1 2 1 0 2 2 2 1 Fungal specific transcription factor domain BTB PF00651.31 KXH60770.1 - 5.7e-05 23.3 0.1 0.0022 18.2 0.0 2.6 2 0 0 2 2 2 1 BTB/POZ domain DUF5082 PF16888.5 KXH60771.1 - 0.091 13.0 0.1 0.57 10.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) MRF_C1 PF13887.6 KXH60771.1 - 0.12 11.5 0.9 0.35 10.1 0.9 1.8 1 1 0 1 1 1 0 Myelin gene regulatory factor -C-terminal domain 1 p450 PF00067.22 KXH60772.1 - 1e-73 248.7 0.0 1.8e-73 247.9 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 Ank PF00023.30 KXH60773.1 - 1.6e-09 37.8 0.5 5.8e-07 29.7 0.2 3.1 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 KXH60773.1 - 8.1e-09 35.6 0.1 3.3e-06 27.3 0.1 2.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXH60773.1 - 1.1e-07 31.6 0.0 0.00011 22.3 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.7 KXH60773.1 - 1.9e-07 31.5 0.0 5.2e-07 30.2 0.0 1.8 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXH60773.1 - 9.8e-05 22.8 0.1 0.00043 20.8 0.0 2.2 2 2 0 2 2 2 1 Ankyrin repeats (many copies) BTB PF00651.31 KXH60775.1 - 0.00059 20.0 0.3 0.0038 17.5 0.1 2.2 2 1 0 2 2 2 1 BTB/POZ domain adh_short_C2 PF13561.6 KXH60777.1 - 8.1e-49 166.3 5.5 3.1e-39 134.9 3.7 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXH60777.1 - 1.1e-43 149.0 3.9 1.4e-43 148.7 3.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXH60777.1 - 1.2e-15 57.9 1.4 1.7e-15 57.4 1.4 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KXH60777.1 - 0.0068 16.3 0.8 0.011 15.7 0.8 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 KXH60777.1 - 0.0069 16.5 0.7 0.011 15.8 0.7 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain THF_DHG_CYH_C PF02882.19 KXH60777.1 - 0.0099 15.2 0.3 0.018 14.4 0.3 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 2-Hacid_dh_C PF02826.19 KXH60777.1 - 0.11 11.8 0.2 0.17 11.2 0.2 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Glycos_transf_2 PF00535.26 KXH60778.1 - 7.9e-36 123.4 0.0 9.4e-36 123.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KXH60778.1 - 5.9e-14 52.5 0.0 7.3e-14 52.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 KXH60778.1 - 1.3e-05 24.9 0.0 1.7e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 KXH60778.1 - 3.6e-05 23.3 0.0 6.2e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 RSN1_7TM PF02714.15 KXH60780.1 - 1.8e-78 263.6 21.2 1.8e-78 263.6 21.2 1.7 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KXH60780.1 - 5e-41 140.1 1.6 1.2e-40 138.8 1.6 1.7 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KXH60780.1 - 2.2e-39 135.5 0.1 3.1e-39 135.0 0.1 1.2 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter SCIMP PF15050.6 KXH60780.1 - 0.21 12.1 1.7 0.82 10.1 0.7 2.4 2 0 0 2 2 2 0 SCIMP protein DUF588 PF04535.12 KXH60780.1 - 0.24 11.2 5.9 0.062 13.1 0.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF588) AATase PF07247.12 KXH60781.1 - 7.2e-20 71.0 0.0 6.8e-16 57.9 0.0 2.1 2 0 0 2 2 2 2 Alcohol acetyltransferase Condensation PF00668.20 KXH60781.1 - 0.092 11.4 0.1 0.51 8.9 0.0 2.0 2 0 0 2 2 2 0 Condensation domain HAD_2 PF13419.6 KXH60783.1 - 3.1e-07 30.6 0.0 5.3e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KXH60783.1 - 0.0017 18.7 0.3 0.006 16.9 0.3 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KXH60783.1 - 0.016 15.6 0.1 0.026 14.9 0.1 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF2226 PF09987.9 KXH60783.1 - 0.025 13.9 0.0 0.032 13.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2226) Hydrolase_6 PF13344.6 KXH60783.1 - 0.032 14.3 0.0 0.2 11.8 0.0 2.0 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase DUF1768 PF08719.11 KXH60784.1 - 8.8e-57 191.8 0.0 1.2e-56 191.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Tim44 PF04280.15 KXH60785.1 - 4.6e-38 130.6 0.0 1.2e-37 129.2 0.0 1.8 2 0 0 2 2 2 1 Tim44-like domain DNA_pol_phi PF04931.13 KXH60785.1 - 3 5.8 10.9 4.4 5.3 10.9 1.2 1 0 0 1 1 1 0 DNA polymerase phi PPL5 PF18168.1 KXH60785.1 - 4.5 6.5 9.4 8.5 5.6 9.4 1.4 1 0 0 1 1 1 0 Prim-pol family 5 Ribosomal_S11 PF00411.19 KXH60786.1 - 2e-09 37.8 0.0 4.7e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S11 Phage_Mu_Gam PF07352.12 KXH60786.1 - 0.063 13.2 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein Peptidase_C97 PF05903.14 KXH60787.1 - 3.9e-34 117.7 0.0 4.9e-34 117.3 0.0 1.1 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.13 KXH60787.1 - 0.0064 16.8 0.0 0.01 16.1 0.0 1.3 1 0 0 1 1 1 1 Lecithin retinol acyltransferase YchF-GTPase_C PF06071.13 KXH60788.1 - 2.8e-33 114.0 0.4 8.3e-33 112.4 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 KXH60788.1 - 9.7e-16 57.9 0.0 2.4e-15 56.6 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase TPR_19 PF14559.6 KXH60788.1 - 0.00015 22.2 0.4 0.16 12.5 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat FeoB_N PF02421.18 KXH60788.1 - 0.001 18.6 0.0 0.0021 17.6 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.21 KXH60788.1 - 0.0027 17.7 0.0 0.0072 16.4 0.0 1.7 1 0 0 1 1 1 1 TGS domain ANAPC3 PF12895.7 KXH60788.1 - 0.013 15.8 0.0 0.025 14.8 0.0 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.14 KXH60788.1 - 0.051 14.2 8.0 2.5 9.0 2.6 4.3 3 0 0 3 3 3 0 Tetratricopeptide repeat BetaGal_dom3 PF13363.6 KXH60788.1 - 0.17 11.4 0.0 0.38 10.4 0.0 1.5 1 0 0 1 1 1 0 Beta-galactosidase, domain 3 TPR_6 PF13174.6 KXH60788.1 - 0.27 12.0 1.0 57 4.7 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 KXH60788.1 - 2.4 8.9 9.5 2.9 8.6 2.1 3.9 3 1 1 4 4 4 0 Tetratricopeptide repeat Peptidase_S8 PF00082.22 KXH60790.1 - 2e-23 83.1 0.2 3.1e-23 82.5 0.2 1.3 1 0 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 KXH60790.1 - 8.1e-09 36.2 0.0 1.6e-08 35.3 0.0 1.5 1 0 0 1 1 1 1 Fn3-like domain Ank_2 PF12796.7 KXH60791.1 - 2.2e-42 143.5 0.0 1.6e-11 44.6 0.0 5.7 1 1 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXH60791.1 - 2.5e-27 94.6 2.7 1.3e-07 31.7 0.1 7.3 5 1 3 8 8 8 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXH60791.1 - 3.4e-27 94.5 2.6 7.1e-08 32.8 0.1 7.6 3 1 6 9 9 9 6 Ankyrin repeats (many copies) Ank PF00023.30 KXH60791.1 - 6e-23 80.2 10.3 0.012 16.0 0.1 9.7 9 0 0 9 9 9 6 Ankyrin repeat Ank_3 PF13606.6 KXH60791.1 - 5.2e-19 66.3 5.9 0.032 14.8 0.1 9.2 10 0 0 10 10 10 4 Ankyrin repeat CorA PF01544.18 KXH60791.1 - 7.9e-09 35.2 1.1 7.9e-09 35.2 1.1 2.0 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein DUF2845 PF11006.8 KXH60791.1 - 0.12 12.5 0.1 9.2 6.5 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2845) SUR7 PF06687.12 KXH60791.1 - 0.41 10.2 3.2 0.71 9.5 3.2 1.3 1 0 0 1 1 1 0 SUR7/PalI family Jnk-SapK_ap_N PF09744.9 KXH60791.1 - 5 7.3 7.9 2.9 8.1 2.3 2.9 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 BTB PF00651.31 KXH60792.1 - 0.0023 18.2 0.0 0.0049 17.1 0.0 1.6 1 1 0 1 1 1 1 BTB/POZ domain ELYS-bb PF16687.5 KXH60793.1 - 0.017 13.8 0.0 0.027 13.1 0.0 1.2 1 0 0 1 1 1 0 beta-propeller of ELYS nucleoporin DUF2457 PF10446.9 KXH60793.1 - 3.1 6.8 12.2 5.5 6.0 12.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) HlyIII PF03006.20 KXH60794.1 - 2.4e-66 223.7 17.1 2.9e-66 223.4 17.1 1.1 1 0 0 1 1 1 1 Haemolysin-III related Mem_trans PF03547.18 KXH60794.1 - 0.029 12.8 0.5 1.3 7.3 0.0 2.1 2 0 0 2 2 2 0 Membrane transport protein TssN PF17555.2 KXH60794.1 - 0.7 9.2 10.3 0.047 13.1 1.5 2.4 1 1 2 3 3 3 0 Type VI secretion system, TssN DUF3285 PF11688.8 KXH60794.1 - 7.1 6.6 5.7 10 6.1 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3285) TMA7 PF09072.10 KXH60795.1 - 6.7e-27 94.1 18.8 7.4e-27 94.0 18.8 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 Pkinase PF00069.25 KXH60796.1 - 2.3e-47 161.6 0.0 1e-46 159.4 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXH60796.1 - 6.2e-22 78.1 0.0 1.3e-21 77.1 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 KXH60796.1 - 0.039 12.9 0.1 0.061 12.3 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase EFF-AFF PF14884.6 KXH60818.1 - 0.081 11.0 0.2 0.11 10.7 0.0 1.3 1 1 0 1 1 1 0 Type I membrane glycoproteins cell-cell fusogen zf-C2H2 PF00096.26 KXH60823.1 - 1.2e-08 35.0 12.2 0.00051 20.4 2.2 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KXH60823.1 - 1.4e-05 25.3 10.9 3.7e-05 24.0 2.0 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KXH60823.1 - 0.00014 22.4 11.4 0.1 13.5 2.4 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KXH60823.1 - 0.011 15.7 0.9 0.011 15.7 0.9 2.0 2 0 0 2 2 2 0 C2H2-type zinc finger zf-met PF12874.7 KXH60823.1 - 0.032 14.6 3.7 0.078 13.4 1.6 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KXH60823.1 - 0.084 13.2 0.4 0.084 13.2 0.4 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding VHS PF00790.19 KXH60829.1 - 2e-22 79.6 0.0 3.9e-22 78.6 0.0 1.5 1 0 0 1 1 1 1 VHS domain GAT PF03127.14 KXH60829.1 - 7.6e-08 32.6 1.0 2.4e-07 30.9 1.0 1.9 1 0 0 1 1 1 1 GAT domain ORC5_C PF14630.6 KXH60829.1 - 0.071 12.6 5.4 0.087 12.3 5.0 1.4 1 1 0 1 1 1 0 Origin recognition complex (ORC) subunit 5 C-terminus YliH PF10799.8 KXH60829.1 - 0.12 12.4 0.2 0.39 10.7 0.1 1.9 1 1 0 1 1 1 0 Biofilm formation protein (YliH/bssR) SR-25 PF10500.9 KXH60829.1 - 0.27 10.8 11.6 0.45 10.1 11.6 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF2461 PF09365.10 KXH60831.1 - 4.8e-84 281.5 0.2 6.6e-84 281.0 0.2 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein (DUF2461) NmrA PF05368.13 KXH60832.1 - 2.5e-17 63.2 0.0 3.1e-17 62.9 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXH60832.1 - 3.2e-12 46.7 0.1 1.2e-11 44.9 0.1 1.9 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KXH60832.1 - 2.8e-07 30.2 0.2 0.00038 20.0 0.1 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family KR PF08659.10 KXH60832.1 - 0.00091 19.2 0.3 0.011 15.7 0.2 2.1 1 1 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 KXH60832.1 - 0.18 10.9 0.2 0.3 10.2 0.2 1.4 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein Fungal_trans PF04082.18 KXH60834.1 - 5.9e-09 35.3 0.2 2e-08 33.6 0.2 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Methyltransf_16 PF10294.9 KXH60835.1 - 1.7e-12 47.5 0.0 2.6e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 KXH60835.1 - 0.016 14.6 0.1 0.02 14.3 0.1 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) GidB PF02527.15 KXH60835.1 - 0.11 11.8 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G DNA_pol_phi PF04931.13 KXH60836.1 - 0.8 7.7 5.4 1.2 7.2 5.4 1.3 1 0 0 1 1 1 0 DNA polymerase phi Surp PF01805.20 KXH60837.1 - 4.3e-10 39.4 0.0 8.3e-10 38.5 0.0 1.5 1 0 0 1 1 1 1 Surp module EF-hand_1 PF00036.32 KXH60838.1 - 3.7e-33 110.6 15.4 3e-09 35.8 2.1 4.5 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.6 KXH60838.1 - 7.2e-30 103.3 4.4 3e-17 62.8 0.4 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KXH60838.1 - 9.1e-27 90.7 9.3 1.3e-08 34.1 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 KXH60838.1 - 1.9e-22 78.8 11.8 5e-11 42.3 0.4 3.8 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 KXH60838.1 - 4.8e-20 70.1 14.5 4.6e-07 29.0 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 KXH60838.1 - 2.3e-14 53.5 0.3 5e-06 26.7 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 KXH60838.1 - 2.4e-07 30.6 0.6 0.002 18.1 0.1 2.2 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_14 PF17959.1 KXH60838.1 - 1.6e-05 25.1 0.1 0.0018 18.6 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain SPARC_Ca_bdg PF10591.9 KXH60838.1 - 0.00016 22.0 0.1 0.033 14.5 0.0 2.2 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EFhand_Ca_insen PF08726.10 KXH60838.1 - 0.011 15.9 0.0 0.021 14.9 0.0 1.5 1 0 0 1 1 1 0 Ca2+ insensitive EF hand Toprim_2 PF13155.6 KXH60838.1 - 0.011 16.1 0.7 1.8 9.1 0.1 2.4 2 1 0 2 2 2 0 Toprim-like UPF0154 PF03672.13 KXH60838.1 - 0.021 14.8 0.0 2 8.5 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) Caleosin PF05042.13 KXH60838.1 - 0.029 14.3 0.1 6.9 6.6 0.0 2.7 2 2 1 3 3 3 0 Caleosin related protein Toprim_4 PF13662.6 KXH60838.1 - 0.032 14.7 1.0 7.2 7.2 0.0 2.9 2 1 1 3 3 3 0 Toprim domain Toprim PF01751.22 KXH60838.1 - 0.067 13.4 0.5 2.4 8.4 0.0 2.5 2 1 0 2 2 2 0 Toprim domain DAO PF01266.24 KXH60839.1 - 4.9e-42 144.8 0.2 5.8e-42 144.5 0.2 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXH60839.1 - 1.6e-06 28.3 0.0 3.6e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KXH60839.1 - 2.8e-06 27.4 0.2 0.024 14.6 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KXH60839.1 - 3.5e-05 23.2 0.0 0.18 11.0 0.0 2.4 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Ribosomal_S25 PF03297.15 KXH60839.1 - 0.0031 17.7 0.6 0.0064 16.7 0.6 1.5 1 0 0 1 1 1 1 S25 ribosomal protein Trp_halogenase PF04820.14 KXH60839.1 - 0.006 15.5 0.0 0.63 8.8 0.0 2.2 2 0 0 2 2 2 1 Tryptophan halogenase Thi4 PF01946.17 KXH60839.1 - 0.0064 15.7 0.0 0.02 14.1 0.0 1.8 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 KXH60839.1 - 0.012 14.8 0.0 1.1 8.3 0.0 2.3 2 0 0 2 2 2 0 FAD binding domain GIDA PF01134.22 KXH60839.1 - 0.013 14.6 0.0 0.046 12.8 0.0 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A Sacchrp_dh_NADP PF03435.18 KXH60839.1 - 0.015 15.5 0.0 0.036 14.3 0.0 1.7 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Glu_dehyd_C PF16912.5 KXH60839.1 - 0.018 14.5 0.0 0.044 13.3 0.0 1.6 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus K_oxygenase PF13434.6 KXH60839.1 - 0.049 12.8 0.0 0.12 11.5 0.0 1.6 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 KXH60839.1 - 0.08 13.5 0.0 0.18 12.4 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MCRA PF06100.11 KXH60839.1 - 0.12 11.2 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 MCRA family TBP PF00352.21 KXH60840.1 - 1.5e-67 223.5 0.1 7.1e-33 112.4 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 KXH60840.1 - 0.00012 22.1 0.0 0.22 11.6 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) Lpp-LpqN PF10738.9 KXH60840.1 - 0.034 13.6 0.1 0.054 13.0 0.1 1.2 1 0 0 1 1 1 0 Probable lipoprotein LpqN DUF4295 PF14128.6 KXH60840.1 - 0.13 12.1 0.1 0.68 9.8 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4295) CENP-T_C PF15511.6 KXH60845.1 - 8e-09 35.6 0.1 9.7e-09 35.3 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 KXH60845.1 - 3.5e-05 24.2 0.1 4.1e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 KXH60845.1 - 8.6e-05 22.6 0.1 0.00013 22.1 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 KXH60845.1 - 0.00036 20.7 0.1 0.00065 19.9 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 KXH60845.1 - 0.00042 20.7 0.1 0.00056 20.2 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 KXH60845.1 - 0.0087 16.1 0.0 0.01 15.9 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KXH60845.1 - 0.023 14.7 0.0 0.027 14.5 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 KXH60845.1 - 0.095 12.5 0.1 0.12 12.2 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) HIGH_NTase1_ass PF16581.5 KXH60845.1 - 0.11 12.5 0.0 0.12 12.4 0.0 1.1 1 0 0 1 1 1 0 Cytidyltransferase-related C-terminal region Histone PF00125.24 KXH60846.1 - 1.6e-51 174.1 2.5 1.8e-51 173.9 2.5 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 KXH60846.1 - 8.4e-06 26.1 0.0 1.3e-05 25.5 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein PAF PF15715.5 KXH60846.1 - 3.4e-05 24.5 1.0 3.9e-05 24.3 1.0 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-T_C PF15511.6 KXH60846.1 - 3.6e-05 23.8 0.4 6.4e-05 23.0 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 KXH60846.1 - 0.0035 17.6 0.3 0.0065 16.7 0.0 1.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KXH60846.1 - 0.028 14.5 0.2 0.046 13.8 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KXH60846.1 - 0.057 13.4 0.0 0.097 12.7 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated PRP3 PF08572.10 KXH60847.1 - 4e-71 239.3 9.0 7.4e-71 238.4 9.0 1.4 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 KXH60847.1 - 3.6e-47 160.1 2.7 3.6e-47 160.1 2.7 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) bZIP_C PF12498.8 KXH60847.1 - 0.015 16.2 0.6 1.2 10.1 0.1 2.9 2 0 0 2 2 2 0 Basic leucine-zipper C terminal BLUF PF04940.12 KXH60847.1 - 0.045 13.9 1.2 5.5 7.2 0.1 3.0 3 0 0 3 3 3 0 Sensors of blue-light using FAD DUF4452 PF14618.6 KXH60849.1 - 6.2e-82 273.5 10.3 7.3e-82 273.3 10.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4452) Abhydrolase_1 PF00561.20 KXH60851.1 - 3.9e-11 43.1 0.4 2.4e-10 40.5 1.0 2.0 2 1 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXH60851.1 - 1.4e-10 40.8 0.0 7.2e-10 38.5 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KXH60851.1 - 7.5e-09 36.5 12.1 7.5e-09 36.5 12.1 2.8 2 1 0 2 2 2 1 Alpha/beta hydrolase family PBP1_TM PF14812.6 KXH60853.1 - 0.1 13.0 5.8 2.2 8.7 4.2 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-B_dimeris PF09026.10 KXH60853.1 - 0.16 12.4 4.2 0.24 11.8 0.0 2.5 3 0 0 3 3 3 0 Centromere protein B dimerisation domain His_Phos_2 PF00328.22 KXH60854.1 - 0.069 12.5 0.0 6.1 6.1 0.0 2.2 2 0 0 2 2 2 0 Histidine phosphatase superfamily (branch 2) Calc_CGRP_IAPP PF00214.19 KXH60854.1 - 0.082 13.3 0.0 0.15 12.5 0.0 1.4 1 0 0 1 1 1 0 Calcitonin / CGRP / IAPP family PPTA PF01239.22 KXH60855.1 - 5.2e-40 134.0 10.9 3.7e-08 32.8 0.1 5.4 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat Pentapeptide PF00805.22 KXH60855.1 - 0.12 12.0 0.2 0.22 11.2 0.2 1.4 1 0 0 1 1 1 0 Pentapeptide repeats (8 copies) Pheromone PF08015.11 KXH60855.1 - 3.4 8.8 7.9 8.6 7.5 7.6 1.9 1 1 0 1 1 1 0 Fungal mating-type pheromone Sporozoite_P67 PF05642.11 KXH60855.1 - 4.7 5.2 4.2 6.9 4.6 4.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen WD40 PF00400.32 KXH60856.1 - 0.0049 17.7 3.0 0.1 13.5 0.1 3.8 5 0 0 5 5 5 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXH60856.1 - 0.014 15.7 0.0 3.1 8.2 0.0 3.5 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain SNARE PF05739.19 KXH60857.1 - 4.3e-09 36.2 1.8 7.9e-09 35.4 1.8 1.5 1 0 0 1 1 1 1 SNARE domain Fusion_gly PF00523.18 KXH60857.1 - 0.1 10.8 0.2 0.15 10.3 0.2 1.1 1 0 0 1 1 1 0 Fusion glycoprotein F0 Metallophos PF00149.28 KXH60858.1 - 1.9e-06 28.5 2.3 6.5e-06 26.8 2.3 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KXH60858.1 - 0.021 15.0 2.1 1.4 9.1 0.2 3.2 3 1 0 3 3 3 0 Calcineurin-like phosphoesterase superfamily domain DUF688 PF05097.12 KXH60858.1 - 0.05 12.8 0.1 0.07 12.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF688) LIM_bind PF01803.16 KXH60859.1 - 8.7e-77 257.9 0.0 8.7e-77 257.9 0.0 4.9 3 1 1 4 4 4 1 LIM-domain binding protein Neisseria_TspB PF05616.13 KXH60859.1 - 3.4 6.0 12.7 7.4 4.9 12.7 1.5 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Tfb5 PF06331.12 KXH60868.1 - 1.8e-24 85.5 0.7 1.9e-24 85.4 0.7 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 DivIC PF04977.15 KXH60877.1 - 0.00083 19.1 5.5 0.00083 19.1 5.5 2.2 2 1 0 2 2 2 1 Septum formation initiator Tmemb_cc2 PF10267.9 KXH60877.1 - 0.00085 18.6 6.4 0.0012 18.1 6.4 1.2 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein DUF812 PF05667.11 KXH60877.1 - 0.0013 17.7 7.1 0.002 17.1 7.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF812) bZIP_1 PF00170.21 KXH60877.1 - 0.0023 18.0 12.6 0.036 14.2 5.8 2.6 2 0 0 2 2 2 1 bZIP transcription factor DUF4795 PF16043.5 KXH60877.1 - 0.0032 17.1 10.9 0.0057 16.3 10.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4795) TMF_DNA_bd PF12329.8 KXH60877.1 - 0.0044 17.0 2.2 0.0044 17.0 2.2 2.5 2 0 0 2 2 2 1 TATA element modulatory factor 1 DNA binding BLOC1_2 PF10046.9 KXH60877.1 - 0.0095 16.2 6.2 0.028 14.7 2.8 2.4 2 0 0 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 ATG16 PF08614.11 KXH60877.1 - 0.011 15.9 12.6 0.023 14.9 12.2 1.7 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Fib_alpha PF08702.10 KXH60877.1 - 0.012 15.8 6.3 0.12 12.5 2.1 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Mod_r PF07200.13 KXH60877.1 - 0.015 15.4 11.0 0.015 15.4 9.5 1.7 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Spc29 PF17082.5 KXH60877.1 - 0.015 15.1 4.2 0.048 13.5 3.6 2.1 2 1 0 2 2 2 0 Spindle Pole Component 29 DUF4315 PF14193.6 KXH60877.1 - 0.018 15.0 4.6 0.057 13.4 4.6 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4315) Laminin_II PF06009.12 KXH60877.1 - 0.022 14.7 2.8 0.031 14.3 1.8 1.6 1 1 0 1 1 1 0 Laminin Domain II Prefoldin_2 PF01920.20 KXH60877.1 - 0.044 13.7 10.9 14 5.6 10.9 2.7 1 1 0 1 1 1 0 Prefoldin subunit NPV_P10 PF05531.12 KXH60877.1 - 0.092 13.2 5.9 1.4 9.4 0.2 2.7 3 0 0 3 3 2 0 Nucleopolyhedrovirus P10 protein YabA PF06156.13 KXH60877.1 - 0.099 13.3 10.8 0.33 11.6 4.5 2.5 1 1 1 2 2 2 0 Initiation control protein YabA SlyX PF04102.12 KXH60877.1 - 0.1 13.3 13.9 0.39 11.4 1.2 2.8 1 1 1 2 2 2 0 SlyX Herpes_UL6 PF01763.16 KXH60877.1 - 0.12 10.8 3.3 0.12 10.9 2.0 1.5 1 1 0 1 1 1 0 Herpesvirus UL6 like Jnk-SapK_ap_N PF09744.9 KXH60877.1 - 0.13 12.4 16.4 0.25 11.6 16.4 1.4 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 7TMR-HDED PF07697.11 KXH60877.1 - 0.34 11.0 7.2 0.63 10.1 7.2 1.4 1 0 0 1 1 1 0 7TM-HD extracellular Aminopep PF10023.9 KXH60877.1 - 0.36 10.1 3.7 0.65 9.3 2.2 2.1 1 1 1 2 2 2 0 Putative aminopeptidase DUF4407 PF14362.6 KXH60877.1 - 0.38 10.0 9.8 0.59 9.4 9.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PspA_IM30 PF04012.12 KXH60877.1 - 0.44 10.1 10.8 0.69 9.4 10.8 1.3 1 0 0 1 1 1 0 PspA/IM30 family DUF1664 PF07889.12 KXH60877.1 - 0.53 10.3 9.3 1 9.4 2.5 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) Atg14 PF10186.9 KXH60877.1 - 0.55 9.3 8.8 0.8 8.7 8.2 1.5 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Uds1 PF15456.6 KXH60877.1 - 0.71 10.0 11.3 9 6.5 0.1 2.6 1 1 1 2 2 2 0 Up-regulated During Septation UL42 PF17638.2 KXH60877.1 - 0.81 9.7 2.7 1.9 8.5 2.7 1.5 1 0 0 1 1 1 0 HCMV UL42 Tropomyosin_1 PF12718.7 KXH60877.1 - 0.94 9.6 15.5 1.4 9.0 14.5 1.7 1 1 0 1 1 1 0 Tropomyosin like Rootletin PF15035.6 KXH60877.1 - 1 9.4 15.3 3.6 7.6 15.3 1.8 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion AATF-Che1 PF13339.6 KXH60877.1 - 1.1 10.0 8.7 38 5.0 8.6 2.6 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor CENP-H PF05837.12 KXH60877.1 - 1.6 9.2 13.7 1.2 9.6 1.3 2.4 1 1 1 2 2 2 0 Centromere protein H (CENP-H) DUF3450 PF11932.8 KXH60877.1 - 1.8 7.8 13.2 0.41 9.9 7.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Ax_dynein_light PF10211.9 KXH60877.1 - 1.9 8.4 15.7 0.35 10.8 7.3 2.3 1 1 1 2 2 2 0 Axonemal dynein light chain CorA PF01544.18 KXH60877.1 - 2.5 7.4 5.1 3 7.1 1.6 2.6 2 1 0 3 3 3 0 CorA-like Mg2+ transporter protein MSG PF02349.15 KXH60877.1 - 2.5 8.3 7.7 0.63 10.3 4.3 1.8 2 0 0 2 2 1 0 Major surface glycoprotein Spc24 PF08286.11 KXH60877.1 - 2.9 8.2 13.2 1.8 8.9 6.1 2.4 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 ZapB PF06005.12 KXH60877.1 - 3.4 8.2 16.5 1.1 9.8 9.4 2.5 1 1 1 2 2 2 0 Cell division protein ZapB Syntaxin-6_N PF09177.11 KXH60877.1 - 3.8 8.1 9.7 76 4.0 9.7 2.5 1 1 0 1 1 1 0 Syntaxin 6, N-terminal UPF0449 PF15136.6 KXH60877.1 - 4.8 7.7 12.1 6.2 7.3 6.9 2.9 1 1 2 3 3 3 0 Uncharacterised protein family UPF0449 XhlA PF10779.9 KXH60877.1 - 4.9 7.4 8.2 1.3 9.2 2.1 2.4 2 0 0 2 2 2 0 Haemolysin XhlA FUSC PF04632.12 KXH60877.1 - 5 5.5 6.1 6.7 5.1 6.1 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family CLZ PF16526.5 KXH60877.1 - 6.1 7.3 12.0 12 6.3 0.7 2.5 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF724 PF05266.14 KXH60877.1 - 6.8 6.5 11.3 0.97 9.2 6.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF724) FlaC_arch PF05377.11 KXH60877.1 - 7.6 7.0 7.9 66 4.0 0.9 3.5 1 1 3 4 4 3 0 Flagella accessory protein C (FlaC) Spc7 PF08317.11 KXH60877.1 - 7.8 5.3 16.0 20 3.9 15.8 1.7 1 1 0 1 1 1 0 Spc7 kinetochore protein GAS PF13851.6 KXH60877.1 - 8.2 5.7 16.2 2.2 7.6 6.5 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding HTH_Tnp_Tc5 PF03221.16 KXH60879.1 - 0.0013 18.7 0.0 0.0057 16.7 0.0 2.1 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain Dynamin_N PF00350.23 KXH60881.1 - 2.1e-34 119.0 0.1 4.5e-34 117.9 0.1 1.6 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 KXH60881.1 - 2.9e-22 79.2 0.0 2.4e-18 66.4 0.0 2.5 2 0 0 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.23 KXH60881.1 - 2.5e-05 24.3 0.1 0.0014 18.7 0.1 2.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KXH60881.1 - 0.022 14.3 0.0 7.1 6.1 0.0 2.6 2 0 0 2 2 2 0 Ferrous iron transport protein B Roc PF08477.13 KXH60881.1 - 0.069 13.4 0.0 0.26 11.5 0.0 2.1 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 KXH60881.1 - 0.072 13.6 0.0 0.16 12.5 0.0 1.7 1 0 0 1 1 1 0 ABC transporter zf-3CxxC PF13695.6 KXH60882.1 - 5e-21 75.1 0.5 6.8e-21 74.6 0.1 1.4 2 0 0 2 2 2 1 Zinc-binding domain RHD_DNA_bind PF00554.22 KXH60882.1 - 0.00066 19.7 0.5 0.0013 18.7 0.1 1.7 1 1 1 2 2 2 1 Rel homology DNA-binding domain zf-3CxxC_2 PF17180.4 KXH60882.1 - 0.026 15.2 5.8 1.1 10.0 0.0 3.0 2 1 0 2 2 2 0 Zinc-binding domain TIG PF01833.24 KXH60882.1 - 0.044 13.9 0.3 0.1 12.7 0.1 1.7 1 1 1 2 2 2 0 IPT/TIG domain Clr5 PF14420.6 KXH60885.1 - 2.5e-05 24.4 1.9 0.00023 21.3 1.9 2.2 1 1 0 1 1 1 1 Clr5 domain DUF3435 PF11917.8 KXH60898.1 - 4e-20 72.1 0.0 4.6e-20 72.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) PhyH PF05721.13 KXH60923.1 - 0.00077 19.8 0.0 0.0012 19.1 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) ubiquitin PF00240.23 KXH60924.1 - 0.042 13.6 0.0 0.92 9.3 0.0 2.4 2 0 0 2 2 2 0 Ubiquitin family TTL PF03133.15 KXH60924.1 - 0.14 11.3 0.1 0.21 10.7 0.1 1.2 1 0 0 1 1 1 0 Tubulin-tyrosine ligase family FAD_binding_7 PF03441.14 KXH60925.1 - 9.4e-77 257.1 1.1 1.4e-76 256.5 1.1 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 KXH60925.1 - 1.1e-35 123.1 0.0 3.5e-35 121.4 0.0 1.8 2 0 0 2 2 2 1 DNA photolyase Velvet PF11754.8 KXH60926.1 - 1.3e-53 182.5 0.2 3e-35 122.3 0.0 3.5 2 2 1 3 3 3 2 Velvet factor MFS_1 PF07690.16 KXH60929.1 - 1.7e-40 139.0 32.9 2.1e-40 138.8 32.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH60929.1 - 1.1e-13 50.8 14.4 1.1e-13 50.8 14.4 2.7 1 1 1 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.13 KXH60929.1 - 2.2e-06 26.4 3.6 4e-06 25.6 3.6 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 KXH60929.1 - 0.00011 20.6 6.0 0.00011 20.6 6.0 2.9 2 1 1 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.7 KXH60929.1 - 0.036 12.9 0.2 0.036 12.9 0.2 2.9 3 1 0 3 3 3 0 MFS_1 like family TcpE PF12648.7 KXH60929.1 - 0.67 10.5 5.0 0.23 12.0 0.7 2.5 2 0 0 2 2 2 0 TcpE family BTB PF00651.31 KXH60931.1 - 2.5e-06 27.7 0.0 4.4e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain MFS_1 PF07690.16 KXH60932.1 - 2.4e-37 128.7 46.0 2.4e-37 128.7 46.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH60932.1 - 0.0097 14.8 31.6 0.0018 17.2 25.0 2.5 1 1 1 2 2 2 1 Sugar (and other) transporter Thioredoxin_6 PF13848.6 KXH60933.1 - 5.3e-17 62.3 0.0 1.9e-08 34.4 0.0 2.1 1 1 1 2 2 2 2 Thioredoxin-like domain Thioredoxin PF00085.20 KXH60933.1 - 0.0012 18.7 0.0 0.0058 16.6 0.0 2.1 3 0 0 3 3 3 1 Thioredoxin DUF1996 PF09362.10 KXH60934.1 - 3.5e-61 207.2 0.9 5.3e-61 206.6 0.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Methyltr_RsmB-F PF01189.17 KXH60934.1 - 8.5e-17 61.5 0.0 1.6e-10 41.0 0.0 2.4 2 0 0 2 2 2 2 16S rRNA methyltransferase RsmB/F Serglycin PF04360.12 KXH60934.1 - 1.5 8.7 5.9 4.8 7.1 5.9 1.8 1 0 0 1 1 1 0 Serglycin Amidohydro_3 PF07969.11 KXH60935.1 - 4.7e-14 52.7 0.4 1.2e-06 28.3 0.0 2.9 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_1 PF01979.20 KXH60935.1 - 3.2e-10 39.8 0.0 4.2e-07 29.6 0.0 2.7 3 0 0 3 3 3 2 Amidohydrolase family Metallophos PF00149.28 KXH60936.1 - 3.6e-16 60.3 2.2 4.7e-16 59.9 2.2 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KXH60936.1 - 5.6e-05 23.4 0.0 0.00013 22.2 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF4159 PF13709.6 KXH60936.1 - 0.0034 16.8 0.0 0.0085 15.5 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4159) Sen15 PF09631.10 KXH60963.1 - 3.4e-26 91.5 0.0 6.1e-26 90.6 0.0 1.4 1 1 0 1 1 1 1 Sen15 protein ADH_N PF08240.12 KXH60964.1 - 6.9e-20 71.0 0.7 1.2e-19 70.2 0.7 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXH60964.1 - 3.2e-16 59.5 0.0 4.7e-16 59.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KXH60964.1 - 6.1e-07 29.1 0.0 9.2e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KXH60964.1 - 0.00018 22.5 0.0 0.00028 21.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KXH60964.1 - 0.0037 16.6 0.0 0.018 14.4 0.0 1.9 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain EXS PF03124.14 KXH61002.1 - 0.0032 16.8 0.3 0.0051 16.2 0.3 1.4 1 0 0 1 1 1 1 EXS family DUF5102 PF17104.5 KXH61003.1 - 0.013 15.6 0.0 0.021 14.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5102) Anti-TRAP PF15777.5 KXH61003.1 - 0.047 13.6 0.0 0.094 12.7 0.0 1.5 1 0 0 1 1 1 0 Tryptophan RNA-binding attenuator protein inhibitory protein Exo_endo_phos_2 PF14529.6 KXH61004.1 - 1e-14 54.4 0.0 2.8e-14 53.0 0.0 1.8 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase BCIP PF13862.6 KXH61005.1 - 1.6e-68 230.6 0.1 2.1e-68 230.2 0.1 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein CM_2 PF01817.21 KXH61006.1 - 0.06 13.7 2.1 8.2 6.9 0.1 2.7 2 2 0 2 2 2 0 Chorismate mutase type II Nitroreductase PF00881.24 KXH61022.1 - 2.1e-15 57.2 0.1 2.8e-15 56.8 0.1 1.1 1 0 0 1 1 1 1 Nitroreductase family EccE PF11203.8 KXH61022.1 - 0.089 13.1 0.2 0.41 11.0 0.0 2.1 1 1 1 2 2 2 0 Putative type VII ESX secretion system translocon, EccE PS_Dcarbxylase PF02666.15 KXH61023.1 - 7.5e-77 257.4 0.0 2.1e-76 255.9 0.0 1.7 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase Biotin_lipoyl PF00364.22 KXH61023.1 - 0.099 12.5 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 Biotin-requiring enzyme Cyt_b-c1_8 PF10890.8 KXH61023.1 - 0.11 12.9 0.0 2.7 8.5 0.0 2.4 2 0 0 2 2 2 0 Cytochrome b-c1 complex subunit 8 ubiquitin PF00240.23 KXH61024.1 - 3.8e-07 29.8 0.0 9.2e-07 28.5 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 KXH61024.1 - 7.7e-05 23.2 0.1 0.00035 21.1 0.1 2.1 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD PF11976.8 KXH61024.1 - 0.095 12.6 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Striatin PF08232.12 KXH61024.1 - 9.4 6.8 11.9 3.2 8.3 7.6 2.3 2 0 0 2 2 2 0 Striatin family zf-CCCH_4 PF18044.1 KXH61025.1 - 0.00012 21.7 5.0 0.00012 21.7 5.0 2.8 2 1 0 2 2 2 1 CCCH-type zinc finger zf-CCCH_2 PF14608.6 KXH61025.1 - 0.0015 19.0 4.3 0.0015 19.0 4.3 2.6 3 0 0 3 3 3 1 RNA-binding, Nab2-type zinc finger zf_CCCH_4 PF18345.1 KXH61025.1 - 0.019 15.0 2.4 0.019 15.0 2.4 3.3 3 1 0 3 3 3 0 Zinc finger domain zf-CCCH_3 PF15663.5 KXH61025.1 - 0.13 12.4 0.5 4.3 7.6 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger containing family zf-CCCH PF00642.24 KXH61025.1 - 0.22 11.5 9.5 0.22 11.5 4.3 2.7 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 KXH61025.1 - 2.3 9.0 5.2 0.38 11.5 0.8 2.0 2 1 0 2 2 2 0 Torus domain SPRY PF00622.28 KXH61026.1 - 2.5e-20 72.8 0.0 4.9e-20 71.8 0.0 1.5 1 0 0 1 1 1 1 SPRY domain HET PF06985.11 KXH61027.1 - 9.7e-29 100.6 0.2 1.6e-28 99.9 0.2 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) adh_short PF00106.25 KXH61028.1 - 5.3e-22 78.2 0.0 1.2e-21 77.1 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXH61028.1 - 2e-12 47.2 0.0 5.2e-12 45.8 0.0 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ADH_zinc_N PF00107.26 KXH61028.1 - 0.015 15.3 0.0 0.027 14.4 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase KR PF08659.10 KXH61028.1 - 0.015 15.2 3.2 0.057 13.3 0.1 2.5 3 0 0 3 3 3 0 KR domain SAM_PNT PF02198.16 KXH61028.1 - 0.028 14.4 0.1 0.063 13.2 0.1 1.6 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain 2-Hacid_dh_C PF02826.19 KXH61028.1 - 0.1 11.9 0.1 0.57 9.5 0.0 1.9 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 KXH61028.1 - 0.12 12.6 0.0 0.37 11.1 0.0 1.7 2 0 0 2 2 2 0 TrkA-N domain 3HCDH_N PF02737.18 KXH61028.1 - 0.5 10.2 1.6 0.7 9.7 0.0 2.0 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GFA PF04828.14 KXH61029.1 - 4.7e-23 81.3 0.9 6.6e-23 80.9 0.9 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme DUF3330 PF11809.8 KXH61029.1 - 0.075 13.1 0.6 0.075 13.1 0.6 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3330) FAD_binding_3 PF01494.19 KXH61030.1 - 1.6e-33 116.4 0.0 4e-33 115.1 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 KXH61030.1 - 1.2e-07 31.3 0.2 1.5e-06 27.7 0.2 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXH61030.1 - 7.4e-07 29.3 0.1 2.4e-06 27.7 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KXH61030.1 - 3.3e-06 26.7 0.0 0.0026 17.1 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase DAO PF01266.24 KXH61030.1 - 2.5e-05 24.0 0.8 0.0025 17.4 1.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KXH61030.1 - 3e-05 23.1 0.2 5.4e-05 22.2 0.1 1.4 1 1 0 1 1 1 1 Tryptophan halogenase Pyr_redox_2 PF07992.14 KXH61030.1 - 3.5e-05 23.2 1.1 0.00047 19.5 0.2 2.1 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXH61030.1 - 5.3e-05 22.1 0.2 0.00059 18.7 0.1 2.0 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 KXH61030.1 - 5.8e-05 23.6 0.5 0.00077 20.0 0.4 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXH61030.1 - 7e-05 22.2 0.3 0.00033 20.0 0.1 1.9 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.7 KXH61030.1 - 7.2e-05 22.3 0.4 0.00031 20.2 0.2 2.1 1 1 1 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KXH61030.1 - 0.00023 20.3 0.3 0.35 9.9 0.1 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein FAD_binding_2 PF00890.24 KXH61030.1 - 0.00081 18.6 0.2 0.0013 18.0 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 KXH61030.1 - 0.034 13.2 0.2 0.065 12.3 0.1 1.5 2 0 0 2 2 2 0 Glucose inhibited division protein A TrkA_N PF02254.18 KXH61030.1 - 0.046 14.0 0.2 0.11 12.8 0.2 1.6 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_9 PF13454.6 KXH61030.1 - 0.1 12.6 0.2 5.7 6.9 0.1 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 KXH61030.1 - 0.14 11.4 0.1 0.24 10.6 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Lipocalin_9 PF17186.4 KXH61031.1 - 1.6e-08 34.9 0.0 3.5e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Lipocalin-like domain CrtC PF07143.11 KXH61031.1 - 3.2e-05 24.7 0.1 9e-05 23.2 0.0 1.8 2 1 0 2 2 2 1 CrtC N-terminal lipocalin domain Methyltransf_23 PF13489.6 KXH61032.1 - 8.8e-23 80.9 0.0 1.6e-22 80.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH61032.1 - 5.1e-13 49.5 0.0 8.8e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH61032.1 - 1.4e-09 38.5 0.0 2.3e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH61032.1 - 3.8e-08 33.3 0.0 8.4e-08 32.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH61032.1 - 5.2e-08 33.5 0.0 8.6e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KXH61032.1 - 0.0062 16.0 0.0 0.013 14.9 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.14 KXH61032.1 - 0.014 15.0 0.0 0.03 13.9 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase small domain CMAS PF02353.20 KXH61032.1 - 0.017 14.4 0.0 0.028 13.7 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase PrmA PF06325.13 KXH61032.1 - 0.14 11.5 0.1 0.25 10.7 0.1 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_2 PF00891.18 KXH61032.1 - 0.15 11.3 0.0 0.26 10.5 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain PRCC PF10253.9 KXH61043.1 - 0.012 16.4 0.4 0.02 15.7 0.4 1.5 1 1 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Amidase PF01425.21 KXH61044.1 - 3.9e-31 108.5 1.8 6.7e-31 107.7 1.8 1.3 1 0 0 1 1 1 1 Amidase MafB PF06255.13 KXH61044.1 - 0.17 11.3 0.0 0.33 10.3 0.0 1.4 2 0 0 2 2 2 0 Neisseria toxin MafB WSC PF01822.19 KXH61046.1 - 8.6e-37 125.2 32.8 2.6e-16 59.6 10.7 5.6 4 1 0 4 4 4 3 WSC domain Peptidase_S15 PF02129.18 KXH61047.1 - 3.4e-15 56.4 0.2 4.7e-15 55.9 0.2 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 KXH61047.1 - 3.9e-11 42.8 0.0 7.1e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KXH61047.1 - 6.8e-11 41.9 0.1 9.2e-11 41.5 0.1 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KXH61047.1 - 1.9e-09 38.5 8.7 1.3e-08 35.7 8.5 1.9 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXH61047.1 - 4.6e-06 26.5 0.1 1e-05 25.3 0.1 1.5 1 1 1 2 2 2 1 alpha/beta hydrolase fold AXE1 PF05448.12 KXH61047.1 - 3.1e-05 22.8 0.1 0.002 16.9 0.1 2.1 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) Abhydrolase_3 PF07859.13 KXH61047.1 - 0.0029 17.5 0.0 0.0054 16.6 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF1100 PF06500.11 KXH61047.1 - 0.032 13.0 0.0 0.044 12.6 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) adh_short PF00106.25 KXH61048.1 - 6.9e-33 113.7 1.3 1.3e-30 106.3 1.3 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXH61048.1 - 2e-20 73.4 0.0 2.8e-20 72.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH61048.1 - 7.2e-08 32.6 0.7 0.0011 18.9 0.1 2.2 2 0 0 2 2 2 2 KR domain RmlD_sub_bind PF04321.17 KXH61048.1 - 0.0056 15.8 0.0 0.0092 15.1 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 KXH61048.1 - 0.028 13.5 0.1 0.041 12.9 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KXH61048.1 - 0.1 12.0 0.0 0.2 11.1 0.0 1.6 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family UPF0181 PF03701.14 KXH61048.1 - 0.17 11.5 0.1 1.2 8.8 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0181) Sugar_tr PF00083.24 KXH61049.1 - 2.2e-64 218.0 20.4 1.6e-39 136.0 7.1 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KXH61049.1 - 1.6e-13 50.3 38.8 2e-12 46.7 30.0 3.1 1 1 2 3 3 3 3 Major Facilitator Superfamily DUF1593 PF07632.11 KXH61050.1 - 1.4e-88 296.7 0.0 1.9e-88 296.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1593) REJ PF02010.15 KXH61050.1 - 0.0021 17.0 0.0 0.0029 16.5 0.0 1.2 1 0 0 1 1 1 1 REJ domain adh_short PF00106.25 KXH61051.1 - 9.1e-23 80.7 0.0 4e-16 59.1 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXH61051.1 - 1.9e-13 50.5 0.0 2.8e-11 43.5 0.0 2.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH61051.1 - 1.1e-07 32.0 0.0 1.9e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXH61051.1 - 0.00015 21.3 0.0 0.0003 20.3 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KXH61051.1 - 0.0095 15.1 0.0 0.014 14.5 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein CTP_transf_like PF01467.26 KXH61052.1 - 1.8e-14 54.1 0.4 4.6e-14 52.8 0.0 2.0 2 1 0 2 2 2 1 Cytidylyltransferase-like VLPT PF07122.11 KXH61052.1 - 0.18 11.5 0.9 0.5 10.2 0.3 2.0 2 0 0 2 2 2 0 Variable length PCR target protein (VLPT) CTP_transf_like PF01467.26 KXH61053.1 - 4.2e-17 62.7 0.0 6.3e-17 62.1 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase-like TPR_12 PF13424.6 KXH61054.1 - 5.9e-40 135.4 20.5 7.1e-13 48.7 1.0 5.2 1 1 3 5 5 5 5 Tetratricopeptide repeat TPR_10 PF13374.6 KXH61054.1 - 1.8e-35 119.8 24.0 5.3e-08 32.5 0.9 7.9 7 1 1 8 8 7 6 Tetratricopeptide repeat TPR_2 PF07719.17 KXH61054.1 - 3.5e-13 48.6 16.4 7e-05 22.7 0.5 6.2 5 0 0 5 5 5 4 Tetratricopeptide repeat NB-ARC PF00931.22 KXH61054.1 - 1.3e-11 44.2 0.0 2.9e-11 43.0 0.0 1.6 1 1 0 1 1 1 1 NB-ARC domain TPR_7 PF13176.6 KXH61054.1 - 1.3e-10 40.6 18.2 0.15 12.2 0.1 7.0 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_1 PF00515.28 KXH61054.1 - 2.1e-10 39.9 12.6 0.00049 19.8 0.2 6.5 6 0 0 6 6 6 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KXH61054.1 - 1.4e-09 38.0 8.1 0.083 13.1 0.1 5.5 2 2 2 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 KXH61054.1 - 4.2e-09 36.5 19.3 0.15 13.0 0.7 7.2 6 1 1 7 7 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 KXH61054.1 - 7.7e-09 35.9 12.7 0.21 12.1 0.1 5.8 4 2 2 6 6 5 4 Tetratricopeptide repeat TPR_MalT PF17874.1 KXH61054.1 - 2.8e-08 33.5 9.5 6.5e-05 22.5 4.0 2.3 2 0 0 2 2 2 2 MalT-like TPR region TPR_16 PF13432.6 KXH61054.1 - 1.9e-07 31.6 18.0 0.13 12.9 0.1 6.6 6 1 0 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 KXH61054.1 - 4.6e-06 26.6 3.5 0.75 10.3 0.1 5.9 6 0 0 6 6 6 1 Tetratricopeptide repeat AAA_22 PF13401.6 KXH61054.1 - 1.7e-05 25.1 0.0 6e-05 23.3 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KXH61054.1 - 1.9e-05 25.1 0.8 0.00012 22.5 0.3 2.5 2 1 0 2 2 1 1 AAA ATPase domain TPR_8 PF13181.6 KXH61054.1 - 0.00012 22.1 7.9 0.5 10.7 0.1 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TniB PF05621.11 KXH61054.1 - 0.00041 19.8 0.0 0.00087 18.7 0.0 1.5 1 0 0 1 1 1 1 Bacterial TniB protein TPR_4 PF07721.14 KXH61054.1 - 0.0011 19.3 11.7 2.9 8.8 0.0 5.8 5 1 0 5 5 5 1 Tetratricopeptide repeat PNP_UDP_1 PF01048.20 KXH61054.1 - 0.0018 17.6 0.0 0.0032 16.8 0.0 1.3 1 0 0 1 1 1 1 Phosphorylase superfamily NACHT PF05729.12 KXH61054.1 - 0.0064 16.4 0.0 0.013 15.4 0.0 1.5 1 0 0 1 1 1 1 NACHT domain SRP54 PF00448.22 KXH61054.1 - 0.0073 16.0 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain IstB_IS21 PF01695.17 KXH61054.1 - 0.0098 15.6 0.0 0.028 14.1 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein TPR_11 PF13414.6 KXH61054.1 - 0.015 14.9 0.1 0.015 14.9 0.1 4.6 5 0 0 5 5 5 0 TPR repeat ATPase_2 PF01637.18 KXH61054.1 - 0.018 14.9 0.0 0.033 14.1 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea TPR_21 PF09976.9 KXH61054.1 - 0.035 13.8 3.9 0.93 9.2 0.2 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat-like domain PPR PF01535.20 KXH61054.1 - 0.041 14.2 1.3 33 5.0 0.0 4.4 4 0 0 4 4 3 0 PPR repeat GMC_oxred_N PF00732.19 KXH61057.1 - 1.8e-55 188.4 0.0 2.6e-55 187.9 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXH61057.1 - 2.5e-28 99.4 0.3 4.7e-28 98.5 0.1 1.6 2 0 0 2 2 2 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KXH61057.1 - 0.00018 20.7 0.1 0.00036 19.7 0.0 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.24 KXH61057.1 - 0.0021 17.7 0.1 2.1 7.8 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase GIDA PF01134.22 KXH61057.1 - 0.0058 15.8 0.1 0.22 10.6 0.0 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 KXH61057.1 - 0.0081 15.4 0.0 0.85 8.8 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXH61057.1 - 0.0091 15.1 0.7 0.12 11.4 0.7 2.1 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KXH61057.1 - 0.027 14.7 0.1 0.072 13.3 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Mqo PF06039.15 KXH61057.1 - 0.12 10.9 0.0 0.2 10.2 0.0 1.3 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) Mtc PF03820.17 KXH61058.1 - 3.9e-119 397.3 0.2 4.7e-119 397.1 0.2 1.1 1 0 0 1 1 1 1 Tricarboxylate carrier Fungal_trans_2 PF11951.8 KXH61064.1 - 0.00045 19.1 0.1 0.00074 18.4 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH61064.1 - 0.075 13.2 1.9 0.15 12.2 1.9 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain AT_hook PF02178.19 KXH61064.1 - 0.2 11.7 2.8 0.56 10.3 2.8 1.8 1 0 0 1 1 1 0 AT hook motif FMO-like PF00743.19 KXH61065.1 - 5.6e-25 87.8 0.0 3.2e-21 75.4 0.0 2.5 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KXH61065.1 - 2e-08 33.9 0.0 1.9e-06 27.3 0.0 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXH61065.1 - 1.3e-07 31.1 0.0 3.6e-07 29.7 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXH61065.1 - 1.6e-07 31.5 0.0 3.3e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KXH61065.1 - 1.9e-05 24.0 0.1 0.0032 16.7 0.0 3.1 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KXH61065.1 - 0.00085 19.0 0.6 0.0036 17.0 0.2 2.1 2 1 1 3 3 3 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KXH61065.1 - 0.0019 18.2 0.0 0.0079 16.2 0.0 2.1 1 1 0 1 1 1 1 FAD-NAD(P)-binding Thi4 PF01946.17 KXH61065.1 - 0.022 14.0 0.1 0.04 13.2 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.27 KXH61065.1 - 0.072 13.7 1.3 0.36 11.4 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Gcd10p PF04189.13 KXH61066.1 - 1.9e-124 414.6 0.0 2.4e-124 414.4 0.0 1.1 1 0 0 1 1 1 1 Gcd10p family FeoB_Cyto PF17910.1 KXH61066.1 - 0.041 14.4 0.1 0.24 12.0 0.1 2.3 1 1 0 1 1 1 0 FeoB cytosolic helical domain P21-Arc PF04062.14 KXH61067.1 - 1.2e-71 240.3 0.0 1.4e-71 240.1 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit COesterase PF00135.28 KXH61069.1 - 2.4e-77 261.0 0.0 3.6e-77 260.4 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXH61069.1 - 2.5e-05 24.2 2.7 8.9e-05 22.4 0.8 2.4 2 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KXH61069.1 - 0.0037 16.8 0.3 0.0057 16.1 0.3 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Zn_clus PF00172.18 KXH61070.1 - 6.3e-06 26.2 11.5 1.2e-05 25.3 11.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3112 PF11309.8 KXH61071.1 - 2.1e-09 37.2 0.4 2.1e-09 37.2 0.4 1.9 2 1 1 3 3 3 1 Protein of unknown function (DUF3112) Acetyltransf_10 PF13673.7 KXH61072.1 - 1.2e-06 28.5 0.0 2.7e-06 27.4 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXH61072.1 - 4.2e-06 27.0 0.1 1.4e-05 25.3 0.1 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXH61072.1 - 0.00021 21.6 0.0 0.00049 20.5 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain OST_IS PF18246.1 KXH61072.1 - 0.026 14.8 0.0 0.049 13.9 0.0 1.4 1 0 0 1 1 1 0 Oligosaccharyltransferase Insert domain Acetyltransf_9 PF13527.7 KXH61072.1 - 0.093 12.8 0.3 0.53 10.4 0.0 2.2 3 1 0 3 3 3 0 Acetyltransferase (GNAT) domain AAA PF00004.29 KXH61073.1 - 1.3e-15 58.0 0.0 2.6e-15 57.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.11 KXH61073.1 - 4.9e-14 52.5 0.0 1.3e-13 51.1 0.0 1.8 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 KXH61073.1 - 7.1e-12 45.4 0.0 4.8e-11 42.7 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.15 KXH61073.1 - 3.4e-08 33.6 0.0 7e-08 32.6 0.0 1.5 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_assoc_2 PF16193.5 KXH61073.1 - 2.1e-07 31.2 0.1 6.1e-07 29.7 0.0 1.9 2 0 0 2 2 1 1 AAA C-terminal domain AAA_30 PF13604.6 KXH61073.1 - 1.5e-06 28.1 0.0 4.3e-06 26.6 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KXH61073.1 - 6.4e-06 26.5 0.0 2.7e-05 24.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KXH61073.1 - 1.3e-05 25.2 0.1 0.00011 22.1 0.0 2.2 1 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KXH61073.1 - 1.3e-05 25.7 0.1 0.00012 22.5 0.0 2.4 2 2 0 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 KXH61073.1 - 3.9e-05 23.7 0.1 0.00013 22.0 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF815 PF05673.13 KXH61073.1 - 6.2e-05 22.3 0.0 0.0001 21.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) DNA_pol3_delta PF06144.13 KXH61073.1 - 6.9e-05 22.7 0.0 0.00013 21.8 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit RuvB_N PF05496.12 KXH61073.1 - 0.00018 21.3 0.0 0.001 18.8 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 KXH61073.1 - 0.0002 21.1 0.0 0.0004 20.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KXH61073.1 - 0.00041 20.7 0.4 0.0011 19.3 0.1 1.9 2 1 0 2 2 1 1 AAA domain AAA_3 PF07726.11 KXH61073.1 - 0.00043 20.2 0.1 0.0028 17.5 0.1 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KXH61073.1 - 0.00069 19.4 0.0 0.0014 18.4 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_14 PF13173.6 KXH61073.1 - 0.0012 18.9 0.0 0.0023 18.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 KXH61073.1 - 0.0017 17.8 0.1 0.0082 15.5 0.1 2.1 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI PhoH PF02562.16 KXH61073.1 - 0.002 17.6 0.3 0.99 8.8 0.0 2.6 1 1 0 2 2 2 1 PhoH-like protein AAA_28 PF13521.6 KXH61073.1 - 0.005 17.1 0.0 0.0098 16.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain TniB PF05621.11 KXH61073.1 - 0.0067 15.8 0.0 0.053 12.9 0.0 2.1 2 0 0 2 2 2 1 Bacterial TniB protein ResIII PF04851.15 KXH61073.1 - 0.012 15.7 0.0 0.06 13.3 0.0 1.9 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit AAA_18 PF13238.6 KXH61073.1 - 0.012 16.2 0.0 0.021 15.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KXH61073.1 - 0.012 15.1 0.0 0.026 14.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase_2 PF01637.18 KXH61073.1 - 0.02 14.8 0.0 0.3 11.0 0.0 2.1 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea AAA_25 PF13481.6 KXH61073.1 - 0.059 12.9 0.0 0.15 11.6 0.0 1.7 2 0 0 2 2 1 0 AAA domain DEAD PF00270.29 KXH61073.1 - 0.069 12.9 0.0 0.44 10.3 0.0 2.1 1 1 1 2 2 2 0 DEAD/DEAH box helicase RNA_helicase PF00910.22 KXH61073.1 - 0.072 13.5 0.0 0.18 12.2 0.0 1.8 1 1 0 1 1 1 0 RNA helicase DUF2075 PF09848.9 KXH61073.1 - 0.075 12.3 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Fringe PF02434.16 KXH61074.1 - 1.1e-05 25.1 1.9 0.00012 21.6 1.8 2.2 1 1 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 KXH61074.1 - 0.027 14.3 0.1 0.1 12.4 0.1 1.8 1 1 1 2 2 2 0 Galactosyltransferase PAN_4 PF14295.6 KXH61074.1 - 0.036 14.0 0.7 0.036 14.0 0.7 2.2 2 0 0 2 2 2 0 PAN domain CAP_N PF01213.19 KXH61074.1 - 1.8 8.0 7.4 3.2 7.1 7.4 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal 2OG-FeII_Oxy_3 PF13640.6 KXH61075.1 - 2.6e-10 41.0 0.1 4.5e-10 40.3 0.1 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Peptidase_M24 PF00557.24 KXH61076.1 - 2.6e-41 141.6 0.0 2.5e-40 138.4 0.0 2.1 1 1 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.18 KXH61076.1 - 0.0023 18.6 0.0 0.0052 17.4 0.0 1.7 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain Sugar_tr PF00083.24 KXH61077.1 - 7.8e-32 110.7 30.9 1.9e-16 60.0 11.5 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KXH61077.1 - 3.3e-26 92.1 42.0 1.3e-15 57.2 9.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Nuc_H_symport PF03825.16 KXH61077.1 - 3.3e-05 23.1 10.6 0.0038 16.3 2.6 2.3 2 0 0 2 2 2 2 Nucleoside H+ symporter MFS_2 PF13347.6 KXH61077.1 - 5.1e-05 22.0 26.5 0.03 12.9 12.7 2.4 1 1 1 2 2 2 2 MFS/sugar transport protein OPT PF03169.15 KXH61078.1 - 9.8e-125 417.5 38.4 1.1e-124 417.3 38.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Phage_holin_5_2 PF16079.5 KXH61078.1 - 0.0096 16.2 0.9 0.0096 16.2 0.9 3.8 4 0 0 4 4 4 1 Phage holin family Hol44, in holin superfamily V CrgA PF06781.12 KXH61078.1 - 0.11 12.6 4.6 0.39 10.8 0.2 3.0 3 0 0 3 3 3 0 Cell division protein CrgA DUF3093 PF11292.8 KXH61078.1 - 1.7 8.9 6.2 5.3 7.3 6.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3093) Pyr_redox_2 PF07992.14 KXH61080.1 - 2.9e-15 56.3 0.0 6.7e-11 42.0 0.0 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXH61080.1 - 2.1e-12 46.9 0.0 5e-12 45.7 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KXH61080.1 - 1.2e-09 37.1 0.0 1.9e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KXH61080.1 - 6.5e-08 32.1 0.0 4.8e-06 26.0 0.0 2.3 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KXH61080.1 - 3.5e-06 27.1 0.0 1.4e-05 25.2 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KXH61080.1 - 1.3e-05 24.1 0.2 0.0067 15.2 0.0 3.0 3 0 0 3 3 3 1 HI0933-like protein Pyr_redox PF00070.27 KXH61080.1 - 1.4e-05 25.5 0.1 0.043 14.4 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KXH61080.1 - 7.1e-05 22.0 0.0 0.00075 18.6 0.0 2.3 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_3 PF01494.19 KXH61080.1 - 0.00019 20.8 0.0 0.0006 19.2 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain FAD_binding_2 PF00890.24 KXH61080.1 - 0.001 18.2 0.1 0.0026 16.9 0.1 1.7 1 0 0 1 1 1 1 FAD binding domain TrkA_N PF02254.18 KXH61080.1 - 0.0031 17.7 0.0 0.0067 16.7 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain DAO PF01266.24 KXH61080.1 - 0.0077 15.9 0.2 0.12 11.9 0.1 2.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KXH61080.1 - 0.019 15.0 0.1 3.6 7.6 0.0 3.0 3 0 0 3 3 3 0 FAD-NAD(P)-binding F420_oxidored PF03807.17 KXH61080.1 - 0.048 14.3 0.0 8.4 7.1 0.0 2.7 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Thi4 PF01946.17 KXH61080.1 - 0.062 12.5 0.0 0.14 11.4 0.0 1.5 1 0 0 1 1 1 0 Thi4 family 2-Hacid_dh_C PF02826.19 KXH61080.1 - 0.083 12.2 0.0 2.4 7.5 0.0 2.3 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 KXH61080.1 - 0.15 11.7 0.0 0.45 10.1 0.0 1.8 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.6 KXH61080.1 - 0.16 12.4 0.0 5.3 7.5 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding Ank_2 PF12796.7 KXH61081.1 - 3.4e-27 94.8 4.7 7.6e-12 45.7 0.0 4.2 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXH61081.1 - 2.6e-18 66.1 6.2 2.3e-05 24.9 0.5 5.5 2 2 4 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 KXH61081.1 - 4.8e-18 64.7 11.8 0.052 14.0 0.2 7.2 7 0 0 7 7 7 5 Ankyrin repeat Ank_3 PF13606.6 KXH61081.1 - 5.8e-18 63.1 3.8 0.31 11.7 0.0 7.3 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 KXH61081.1 - 2e-14 53.4 3.2 0.015 15.6 0.3 5.6 2 2 3 5 5 5 4 Ankyrin repeats (many copies) DUF1843 PF08898.10 KXH61081.1 - 0.034 14.6 3.6 59 4.3 0.1 4.8 4 1 0 4 4 4 0 Domain of unknown function (DUF1843) p450 PF00067.22 KXH61122.1 - 0.00025 19.9 0.0 0.00025 19.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF5482 PF17579.2 KXH61122.1 - 0.063 13.2 0.0 0.067 13.1 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5482) Cnd3 PF12719.7 KXH61123.1 - 0.048 12.8 0.2 0.055 12.7 0.2 1.0 1 0 0 1 1 1 0 Nuclear condensing complex subunits, C-term domain ketoacyl-synt PF00109.26 KXH61164.1 - 1.7e-74 250.6 0.0 3.8e-74 249.5 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KXH61164.1 - 5e-46 156.9 0.0 9.6e-46 155.9 0.0 1.5 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.21 KXH61164.1 - 8.7e-46 156.9 0.0 1.5e-45 156.1 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 KXH61164.1 - 2e-45 155.3 0.0 3e-45 154.8 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 KXH61164.1 - 7e-29 100.2 1.8 7.9e-29 100.1 0.1 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.25 KXH61164.1 - 4e-11 42.8 0.0 1e-10 41.4 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase KAsynt_C_assoc PF16197.5 KXH61164.1 - 1.1e-09 38.7 0.0 2.7e-09 37.5 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension adh_short_C2 PF13561.6 KXH61164.1 - 0.00014 21.5 0.0 0.00031 20.4 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Thiolase_N PF00108.23 KXH61164.1 - 0.00039 19.9 0.1 0.00073 19.0 0.1 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain SAT PF16073.5 KXH61164.1 - 0.0019 18.0 0.2 0.011 15.5 0.2 2.1 1 1 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Methyltransf_31 PF13847.6 KXH61164.1 - 0.038 13.8 0.0 0.098 12.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain PP-binding PF00550.25 KXH61164.1 - 0.071 13.5 0.0 0.23 11.9 0.0 1.9 1 0 0 1 1 1 0 Phosphopantetheine attachment site CBM_1 PF00734.18 KXH61165.1 - 1.9e-11 43.7 15.9 1.9e-11 43.7 15.9 2.8 3 0 0 3 3 3 1 Fungal cellulose binding domain Lipase_GDSL_2 PF13472.6 KXH61165.1 - 7.7e-08 32.9 0.4 1.3e-07 32.2 0.4 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KXH61165.1 - 0.00016 21.7 0.0 0.00023 21.2 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Acetyltransf_1 PF00583.25 KXH61167.1 - 1.1e-12 48.2 0.0 1.5e-12 47.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXH61167.1 - 8.5e-09 35.4 0.0 1e-08 35.2 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXH61167.1 - 1.4e-08 35.0 0.0 2.2e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXH61167.1 - 0.0004 20.3 0.0 0.00068 19.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 KXH61167.1 - 0.0008 19.5 0.0 0.0016 18.6 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase NMT PF01233.19 KXH61167.1 - 0.00088 19.1 0.0 0.0011 18.9 0.0 1.2 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_3 PF13302.7 KXH61167.1 - 0.031 14.9 0.0 0.037 14.7 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KXH61167.1 - 0.045 13.8 0.0 0.057 13.5 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 KXH61167.1 - 0.077 13.0 0.0 0.2 11.7 0.0 1.6 1 1 1 2 2 2 0 ESCO1/2 acetyl-transferase Peptidase_M20 PF01546.28 KXH61170.1 - 1.3e-31 109.9 0.0 1.8e-31 109.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KXH61170.1 - 0.00032 20.6 0.0 0.00065 19.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KXH61170.1 - 0.014 15.1 0.0 0.024 14.3 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M28 PriA_C PF18074.1 KXH61170.1 - 0.12 13.3 0.0 0.38 11.6 0.0 1.8 2 0 0 2 2 2 0 Primosomal protein N C-terminal domain Fungal_lectin PF07938.12 KXH61171.1 - 0.00087 18.8 0.5 0.0043 16.5 0.2 2.2 1 1 1 2 2 2 2 Fungal fucose-specific lectin DUF3328 PF11807.8 KXH61171.1 - 0.16 11.7 0.1 0.23 11.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) WW PF00397.26 KXH61172.1 - 8.3e-13 48.2 1.1 2.2e-12 46.8 1.1 1.8 1 0 0 1 1 1 1 WW domain Shadoo PF14999.6 KXH61172.1 - 8.1 6.5 18.7 5.5 7.1 2.7 3.4 3 0 0 3 3 3 0 Shadow of prion protein, neuroprotective Methyltransf_23 PF13489.6 KXH61173.1 - 5e-20 72.0 0.0 7.7e-20 71.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH61173.1 - 1.1e-09 38.9 0.0 4e-09 37.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH61173.1 - 4.4e-08 33.1 0.0 4.8e-07 29.7 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH61173.1 - 8.4e-08 32.9 0.0 3.6e-07 30.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH61173.1 - 3.5e-07 30.8 0.0 8e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXH61173.1 - 0.0061 16.1 0.0 0.0097 15.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 KXH61173.1 - 0.018 14.8 0.0 0.027 14.2 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 KXH61173.1 - 0.06 12.7 0.0 0.15 11.4 0.0 1.6 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_2 PF00891.18 KXH61173.1 - 0.09 12.1 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Porin_OmpG_1_2 PF16946.5 KXH61173.1 - 0.11 11.7 0.2 0.17 11.1 0.2 1.2 1 0 0 1 1 1 0 OMPG-porin 1 family Peptidase_C23 PF05379.11 KXH61174.1 - 0.0001 22.4 0.0 0.00021 21.4 0.0 1.5 1 0 0 1 1 1 1 Carlavirus endopeptidase MTCP1 PF08991.10 KXH61175.1 - 0.084 13.1 0.1 0.12 12.7 0.1 1.2 1 0 0 1 1 1 0 Mature-T-Cell Proliferation I type CX9C PF16860.5 KXH61175.1 - 0.094 12.7 0.2 0.14 12.2 0.2 1.2 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, GerE PF00196.19 KXH61175.1 - 0.2 11.2 0.0 0.41 10.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family PH_10 PF15411.6 KXH61176.1 - 5.6e-41 139.6 0.2 1.2e-40 138.6 0.2 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain CDC24 PF06395.11 KXH61176.1 - 2.9e-32 110.8 0.0 6.3e-32 109.7 0.0 1.6 1 0 0 1 1 1 1 CDC24 Calponin RhoGEF PF00621.20 KXH61176.1 - 3.4e-29 102.4 0.0 5.5e-29 101.7 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain PB1 PF00564.24 KXH61176.1 - 2.2e-08 33.9 0.0 5.1e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 PB1 domain DUF5319 PF17252.2 KXH61176.1 - 0.16 12.2 0.3 0.56 10.5 0.0 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5319) DUF3613 PF12266.8 KXH61177.1 - 0.07 12.9 0.2 4 7.3 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3613) WD40 PF00400.32 KXH61178.1 - 7.2e-29 99.4 6.7 9.2e-05 23.2 0.0 7.0 6 0 0 6 6 6 6 WD domain, G-beta repeat F-box-like PF12937.7 KXH61178.1 - 1.1e-10 41.2 1.8 1.6e-10 40.7 0.4 2.0 2 0 0 2 2 2 1 F-box-like ANAPC4_WD40 PF12894.7 KXH61178.1 - 5.6e-06 26.6 0.3 0.036 14.4 0.0 4.0 3 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KXH61178.1 - 0.0007 18.4 0.1 0.16 10.6 0.0 2.4 2 0 0 2 2 2 2 Nucleoporin Nup120/160 F-box PF00646.33 KXH61178.1 - 0.00071 19.4 0.8 0.0014 18.4 0.1 1.9 2 0 0 2 2 2 1 F-box domain WD40_like PF17005.5 KXH61178.1 - 0.0059 16.0 0.2 0.048 13.0 0.1 2.3 2 1 0 2 2 2 1 WD40-like domain F-box_4 PF15966.5 KXH61178.1 - 0.02 14.7 0.0 0.059 13.3 0.0 1.8 1 0 0 1 1 1 0 F-box Snf7 PF03357.21 KXH61179.1 - 1.6e-44 151.5 14.5 1.9e-44 151.3 14.5 1.1 1 0 0 1 1 1 1 Snf7 NPV_P10 PF05531.12 KXH61179.1 - 0.0021 18.4 9.1 1.2 9.7 0.1 3.2 2 1 0 2 2 2 2 Nucleopolyhedrovirus P10 protein Mod_r PF07200.13 KXH61179.1 - 0.0072 16.4 7.2 0.0072 16.4 7.2 2.0 1 1 1 2 2 2 1 Modifier of rudimentary (Mod(r)) protein CENP-F_leu_zip PF10473.9 KXH61179.1 - 0.038 14.0 11.2 2.3 8.3 9.2 2.6 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FapA PF03961.13 KXH61179.1 - 0.057 12.0 9.8 0.38 9.3 3.8 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A Alpha-2-MRAP_C PF06401.11 KXH61179.1 - 0.075 13.0 5.7 0.58 10.1 5.2 2.1 1 1 1 2 2 2 0 Alpha-2-macroglobulin RAP, C-terminal domain Prefoldin PF02996.17 KXH61179.1 - 0.08 12.9 9.2 2.5 8.0 0.1 3.6 3 1 1 4 4 4 0 Prefoldin subunit CLZ PF16526.5 KXH61179.1 - 0.17 12.3 10.0 0.51 10.7 0.0 3.7 3 1 1 4 4 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF4844 PF16133.5 KXH61179.1 - 0.27 11.8 4.3 1.5 9.4 4.3 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4844) Endotoxin_N PF03945.14 KXH61179.1 - 0.28 10.9 6.8 0.46 10.2 0.6 2.1 1 1 1 2 2 2 0 delta endotoxin, N-terminal domain DUF848 PF05852.11 KXH61179.1 - 0.28 11.3 6.0 0.33 11.1 4.6 1.8 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) ING PF12998.7 KXH61179.1 - 0.33 11.6 6.3 0.38 11.4 4.2 2.0 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding Muted PF14942.6 KXH61179.1 - 0.6 10.4 9.9 3.6 7.9 5.9 2.4 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein FlxA PF14282.6 KXH61179.1 - 0.64 10.0 14.2 0.59 10.1 12.4 1.8 1 1 0 1 1 1 0 FlxA-like protein DUF4407 PF14362.6 KXH61179.1 - 0.91 8.8 8.6 1.5 8.1 8.6 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) CorA PF01544.18 KXH61179.1 - 1.1 8.5 4.8 15 4.8 4.4 2.0 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein DUF4337 PF14235.6 KXH61179.1 - 1.3 9.1 8.2 5.6 7.1 2.7 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) Atg14 PF10186.9 KXH61179.1 - 1.4 7.9 9.3 3.4 6.7 9.1 1.6 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF2205 PF10224.9 KXH61179.1 - 1.5 8.9 7.9 0.35 10.9 2.6 2.6 2 1 1 3 3 3 0 Short coiled-coil protein DASH_Dam1 PF08653.10 KXH61179.1 - 1.7 8.5 4.7 11 5.9 0.1 3.3 3 0 0 3 3 3 0 DASH complex subunit Dam1 FlaC_arch PF05377.11 KXH61179.1 - 1.7 9.1 12.1 3.5 8.1 0.1 3.9 2 1 2 4 4 3 0 Flagella accessory protein C (FlaC) FUSC PF04632.12 KXH61179.1 - 2.8 6.4 3.3 5.3 5.4 0.6 1.8 1 1 1 2 2 2 0 Fusaric acid resistance protein family DUF4446 PF14584.6 KXH61179.1 - 3.1 7.8 8.4 5.1 7.1 1.8 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF4446) Uso1_p115_C PF04871.13 KXH61179.1 - 5.2 7.5 18.7 1.3e+02 2.9 17.6 2.6 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region TMPIT PF07851.13 KXH61179.1 - 7 5.8 8.8 7.8 5.6 6.5 1.8 1 1 1 2 2 2 0 TMPIT-like protein Ion_trans PF00520.31 KXH61180.1 - 0.00036 19.9 15.9 0.012 14.8 18.1 2.3 1 1 1 2 2 2 1 Ion transport protein PKD_channel PF08016.12 KXH61180.1 - 0.77 8.4 11.6 1.7 7.2 1.6 2.3 2 0 0 2 2 2 0 Polycystin cation channel DUF1961 PF09224.11 KXH61181.1 - 1.3e-101 338.4 0.0 1.5e-101 338.2 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1961) DUF1080 PF06439.11 KXH61181.1 - 0.034 14.2 0.0 0.039 14.0 0.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1080) DSPc PF00782.20 KXH61183.1 - 1.2e-11 44.6 0.0 5.7e-05 22.9 0.0 3.3 3 0 0 3 3 3 3 Dual specificity phosphatase, catalytic domain rRNA_methylase PF06962.12 KXH61183.1 - 0.0012 18.9 0.9 0.0019 18.2 0.2 1.7 2 0 0 2 2 2 1 Putative rRNA methylase DUF1840 PF08895.11 KXH61183.1 - 0.41 11.0 2.8 5.8 7.3 0.8 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) zf-H2C2_2 PF13465.6 KXH61184.1 - 0.0087 16.5 0.3 0.0087 16.5 0.3 3.3 5 0 0 5 5 5 1 Zinc-finger double domain zf-C2H2 PF00096.26 KXH61184.1 - 0.027 14.9 22.2 0.05 14.1 0.8 5.0 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-CHCC PF10276.9 KXH61184.1 - 0.14 12.2 2.4 6.8 6.8 0.3 2.5 2 0 0 2 2 2 0 Zinc-finger domain zf-C2H2_4 PF13894.6 KXH61184.1 - 4.9 8.3 23.9 0.23 12.4 1.4 5.1 4 0 0 4 4 4 0 C2H2-type zinc finger RRM_1 PF00076.22 KXH61213.1 - 6e-10 38.8 0.0 2.1e-09 37.0 0.0 2.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CMS1 PF14617.6 KXH61214.1 - 5.6e-48 163.5 0.4 6.8e-48 163.2 0.4 1.1 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit NUDIX PF00293.28 KXH61265.1 - 6.5e-18 65.0 0.2 8.5e-18 64.7 0.2 1.1 1 0 0 1 1 1 1 NUDIX domain PAP1 PF08601.10 KXH61270.1 - 8.1e-86 289.1 53.8 9.8e-62 209.8 4.5 4.1 1 1 3 4 4 4 3 Transcription factor PAP1 bZIP_1 PF00170.21 KXH61270.1 - 7.6e-11 41.9 11.9 1.7e-10 40.8 11.9 1.6 1 0 0 1 1 1 1 bZIP transcription factor Spc29 PF17082.5 KXH61270.1 - 0.0012 18.8 2.6 0.0012 18.8 2.6 1.8 2 0 0 2 2 2 1 Spindle Pole Component 29 SlyX PF04102.12 KXH61270.1 - 0.0051 17.4 1.6 0.0053 17.3 0.2 1.8 2 0 0 2 2 1 1 SlyX bZIP_2 PF07716.15 KXH61270.1 - 0.0051 16.9 12.1 0.038 14.1 12.1 2.1 1 1 0 1 1 1 1 Basic region leucine zipper DUF812 PF05667.11 KXH61270.1 - 0.007 15.3 7.9 0.012 14.5 7.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF812) APG6_N PF17675.1 KXH61270.1 - 0.0092 16.5 4.4 0.02 15.4 4.4 1.5 1 0 0 1 1 1 1 Apg6 coiled-coil region SHE3 PF17078.5 KXH61270.1 - 0.01 15.5 6.1 0.01 15.5 6.1 1.9 3 0 0 3 3 2 0 SWI5-dependent HO expression protein 3 Prominin PF05478.11 KXH61270.1 - 0.02 12.9 0.7 0.03 12.3 0.7 1.1 1 0 0 1 1 1 0 Prominin IFT57 PF10498.9 KXH61270.1 - 0.031 13.3 6.0 0.06 12.3 6.0 1.4 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 NPV_P10 PF05531.12 KXH61270.1 - 0.048 14.1 0.8 0.048 14.1 0.8 1.9 2 0 0 2 2 1 0 Nucleopolyhedrovirus P10 protein DUF5082 PF16888.5 KXH61270.1 - 0.11 12.8 5.9 0.37 11.1 5.9 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) Cluap1 PF10234.9 KXH61270.1 - 0.14 11.6 6.3 0.3 10.5 6.3 1.5 1 0 0 1 1 1 0 Clusterin-associated protein-1 Herpes_UL6 PF01763.16 KXH61270.1 - 0.17 10.4 1.3 0.24 9.9 1.3 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like DOG1 PF14144.6 KXH61270.1 - 0.18 12.1 0.1 0.43 10.8 0.1 1.6 1 0 0 1 1 1 0 Seed dormancy control UPF0242 PF06785.11 KXH61270.1 - 0.18 11.9 5.8 0.36 10.9 5.8 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF1664 PF07889.12 KXH61270.1 - 0.19 11.8 0.6 0.5 10.4 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) JIP_LZII PF16471.5 KXH61270.1 - 0.3 11.3 4.5 3.9 7.7 2.8 2.4 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II Atg14 PF10186.9 KXH61270.1 - 0.38 9.8 7.3 0.77 8.8 7.3 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 V_ATPase_I PF01496.19 KXH61270.1 - 0.42 8.5 2.1 0.7 7.7 2.1 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TolA_bind_tri PF16331.5 KXH61270.1 - 0.43 10.7 2.8 0.44 10.7 0.2 2.1 2 0 0 2 2 2 0 TolA binding protein trimerisation FlaC_arch PF05377.11 KXH61270.1 - 0.58 10.6 2.6 1.2 9.5 2.6 1.5 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) Jnk-SapK_ap_N PF09744.9 KXH61270.1 - 0.67 10.2 7.2 1.4 9.2 7.2 1.4 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 TMCO5 PF14992.6 KXH61270.1 - 0.68 9.5 5.7 1.3 8.5 5.7 1.4 1 0 0 1 1 1 0 TMCO5 family DUF4407 PF14362.6 KXH61270.1 - 0.94 8.8 4.1 1.5 8.1 4.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF724 PF05266.14 KXH61270.1 - 1 9.1 7.1 1.7 8.4 7.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) bZIP_Maf PF03131.17 KXH61270.1 - 1.3 9.6 11.4 0.38 11.3 8.4 1.7 2 0 0 2 2 1 0 bZIP Maf transcription factor Snapin_Pallidin PF14712.6 KXH61270.1 - 1.6 9.2 6.7 0.94 9.9 1.1 2.4 2 0 0 2 2 2 0 Snapin/Pallidin DivIC PF04977.15 KXH61270.1 - 1.7 8.5 4.5 4.3 7.2 4.5 1.7 1 0 0 1 1 1 0 Septum formation initiator Prefoldin_2 PF01920.20 KXH61270.1 - 4.9 7.2 10.4 0.72 9.8 6.1 1.8 2 0 0 2 2 1 0 Prefoldin subunit TMPIT PF07851.13 KXH61270.1 - 5.9 6.0 7.0 1.8 7.8 3.2 1.8 2 0 0 2 2 2 0 TMPIT-like protein LegC3_N PF18654.1 KXH61270.1 - 7.2 5.8 12.0 1.8 7.7 8.5 1.7 2 0 0 2 2 2 0 LegC3 N-terminal coiled-coil domain XhlA PF10779.9 KXH61270.1 - 7.9 6.8 5.7 16 5.7 5.7 1.5 1 0 0 1 1 1 0 Haemolysin XhlA Pyr_redox_2 PF07992.14 KXH61295.1 - 6.4e-22 78.1 0.0 7.6e-22 77.9 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXH61295.1 - 8.7e-13 48.6 0.2 1.6e-12 47.8 0.2 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXH61295.1 - 0.00088 18.5 0.1 0.0017 17.6 0.0 1.4 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.12 KXH61295.1 - 0.003 16.7 0.0 0.0051 15.9 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KXH61295.1 - 0.0042 16.4 0.1 0.0063 15.8 0.1 1.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXH61295.1 - 0.013 15.5 0.3 6.1 6.8 0.0 3.1 3 0 0 3 3 3 0 FAD-NAD(P)-binding Trp_halogenase PF04820.14 KXH61295.1 - 0.014 14.3 0.1 3 6.6 0.1 2.1 2 0 0 2 2 2 0 Tryptophan halogenase HI0933_like PF03486.14 KXH61295.1 - 0.026 13.2 0.3 0.55 8.9 0.2 2.1 1 1 1 2 2 2 0 HI0933-like protein DAO PF01266.24 KXH61295.1 - 0.042 13.4 1.1 0.25 10.9 0.2 2.5 3 0 0 3 3 3 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KXH61295.1 - 0.059 12.6 0.0 2.8 7.1 0.1 2.1 2 0 0 2 2 2 0 FAD binding domain FLYWCH_N PF15423.6 KXH61295.1 - 0.15 12.1 0.2 25 5.0 0.0 2.9 3 0 0 3 3 3 0 FLYWCH-type zinc finger-containing protein HET PF06985.11 KXH61321.1 - 5.1e-17 62.6 0.1 8.2e-17 61.9 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) AA_permease_2 PF13520.6 KXH61322.1 - 1.1e-79 268.3 34.9 1.3e-79 268.0 34.9 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXH61322.1 - 1.7e-20 73.1 29.3 2.2e-20 72.7 29.3 1.1 1 0 0 1 1 1 1 Amino acid permease DUF2619 PF10942.8 KXH61322.1 - 1.8 8.7 7.1 1.4 9.0 0.5 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2619) CHZ PF09649.10 KXH61323.1 - 3e-05 23.4 0.8 6e-05 22.4 0.8 1.5 1 0 0 1 1 1 1 Histone chaperone domain CHZ Zn_clus PF00172.18 KXH61325.1 - 0.00035 20.6 0.8 0.00086 19.4 0.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain bZIP_2 PF07716.15 KXH61325.1 - 9.5 6.4 11.5 3.4 7.8 6.6 2.2 2 0 0 2 2 2 0 Basic region leucine zipper Peptidase_S8 PF00082.22 KXH61327.1 - 1.7e-34 119.5 0.0 7.6e-34 117.3 0.0 2.1 1 1 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 KXH61327.1 - 4.8e-12 46.6 0.8 1.6e-11 44.9 0.0 2.2 2 0 0 2 2 2 1 Fn3-like domain FixG_C PF11614.8 KXH61327.1 - 0.032 14.5 0.0 0.16 12.2 0.0 2.2 2 0 0 2 2 2 0 IG-like fold at C-terminal of FixG, putative oxidoreductase DUF916 PF06030.12 KXH61327.1 - 0.053 13.6 0.2 0.19 11.8 0.2 1.9 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF916) MSP1_C PF07462.11 KXH61327.1 - 3.5 6.2 4.7 6.7 5.3 4.7 1.4 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus zf-C2H2 PF00096.26 KXH61328.1 - 0.25 11.9 7.1 0.25 11.9 0.0 3.6 3 0 0 3 3 3 0 Zinc finger, C2H2 type CUE PF02845.16 KXH61329.1 - 3.3e-06 26.7 0.0 5.8e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 CUE domain NOA36 PF06524.12 KXH61329.1 - 1 8.6 4.4 1.6 7.9 4.4 1.2 1 0 0 1 1 1 0 NOA36 protein Ribosomal_S10 PF00338.22 KXH61330.1 - 3.7e-26 91.2 0.2 4.7e-26 90.9 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Fibrillarin_2 PF10113.9 KXH61330.1 - 0.00078 18.2 0.0 0.00086 18.1 0.0 1.1 1 0 0 1 1 1 1 Fibrillarin-like archaeal protein PriA_C PF18074.1 KXH61330.1 - 0.16 12.8 0.4 0.71 10.7 0.0 1.9 2 0 0 2 2 2 0 Primosomal protein N C-terminal domain Cellulase PF00150.18 KXH61331.1 - 9.8e-19 67.8 0.2 2.5e-18 66.5 0.2 1.6 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) p450 PF00067.22 KXH61332.1 - 3.7e-60 204.0 0.0 4.9e-60 203.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Frag1 PF10277.9 KXH61333.1 - 3.4e-36 124.8 10.9 3.4e-36 124.8 10.9 2.7 2 0 0 2 2 2 1 Frag1/DRAM/Sfk1 family Exo_endo_phos PF03372.23 KXH61333.1 - 0.03 13.8 0.0 0.073 12.6 0.0 1.6 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family U3_assoc_6 PF08640.11 KXH61334.1 - 5.1e-28 97.0 5.0 1.9e-27 95.1 1.1 2.6 2 1 1 3 3 3 1 U3 small nucleolar RNA-associated protein 6 NRDE-2 PF08424.10 KXH61334.1 - 7.9e-05 21.9 0.5 0.00016 20.9 0.2 1.6 2 0 0 2 2 2 1 NRDE-2, necessary for RNA interference TPR_14 PF13428.6 KXH61334.1 - 0.0062 17.3 0.0 15 6.7 0.0 3.7 3 1 1 4 4 4 2 Tetratricopeptide repeat RPN2_C PF18004.1 KXH61334.1 - 4.1 7.3 6.6 7.5 6.5 6.6 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain EVE PF01878.18 KXH61335.1 - 2.1e-42 144.5 0.1 2.1e-42 144.5 0.1 1.8 2 0 0 2 2 2 1 EVE domain SRP-alpha_N PF04086.13 KXH61335.1 - 6.5 6.6 13.6 12 5.7 13.6 1.4 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal PALP PF00291.25 KXH61336.1 - 5.6e-61 206.5 6.9 6.3e-61 206.3 6.9 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF2484 PF10658.9 KXH61338.1 - 0.1 12.9 0.7 0.1 12.9 0.7 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2484) PLDc_N PF13396.6 KXH61338.1 - 0.11 12.5 2.6 0.74 9.8 2.6 2.5 1 0 0 1 1 1 0 Phospholipase_D-nuclease N-terminal PBP PF01161.20 KXH61339.1 - 2.6e-17 63.3 0.1 4.2e-17 62.7 0.1 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein DUF1179 PF06678.11 KXH61339.1 - 0.71 9.9 5.0 27 4.8 1.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1179) p450 PF00067.22 KXH61340.1 - 2.1e-55 188.3 0.0 9.7e-55 186.1 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 Amidase PF01425.21 KXH61341.1 - 1.5e-70 238.4 0.8 1.8e-67 228.3 0.1 2.1 2 0 0 2 2 2 2 Amidase Methyltransf_23 PF13489.6 KXH61342.1 - 1.5e-24 86.7 0.0 2.1e-24 86.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH61342.1 - 6.7e-09 36.3 0.0 1.6e-08 35.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH61342.1 - 7.4e-07 29.8 0.0 3.6e-06 27.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH61342.1 - 2.1e-06 28.3 0.0 4.4e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH61342.1 - 2.2e-05 24.3 0.0 0.035 13.9 0.0 2.1 2 0 0 2 2 2 2 Methyltransferase domain Ubie_methyltran PF01209.18 KXH61342.1 - 0.0043 16.4 0.0 0.045 13.1 0.0 2.3 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family PrmA PF06325.13 KXH61342.1 - 0.017 14.6 0.0 0.027 13.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.19 KXH61342.1 - 0.017 15.2 0.0 0.025 14.7 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_16 PF10294.9 KXH61342.1 - 0.043 13.5 0.0 0.064 13.0 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase Sugar_tr PF00083.24 KXH61343.1 - 4.1e-81 273.1 27.4 4.9e-81 272.9 27.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH61343.1 - 1.9e-17 63.2 30.6 1.9e-17 63.2 30.6 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily PAH PF02671.21 KXH61344.1 - 8.8e-06 25.8 0.0 2.8e-05 24.2 0.1 1.7 2 0 0 2 2 2 1 Paired amphipathic helix repeat HET PF06985.11 KXH61345.1 - 1.5e-40 138.9 0.1 2.5e-40 138.2 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HET PF06985.11 KXH61346.1 - 4.8e-23 82.1 0.0 9.2e-23 81.2 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Sugar_tr PF00083.24 KXH61348.1 - 3e-87 293.3 17.6 3.7e-87 293.1 17.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH61348.1 - 3.9e-36 124.7 42.8 9.7e-28 97.1 27.0 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KXH61348.1 - 9.8e-05 21.0 7.5 0.00033 19.2 2.9 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Folate_carrier PF01770.18 KXH61348.1 - 0.0029 16.4 0.1 0.65 8.7 0.0 2.2 2 0 0 2 2 2 2 Reduced folate carrier DUF3792 PF12670.7 KXH61348.1 - 0.017 15.2 0.3 0.017 15.2 0.3 4.5 5 0 0 5 5 5 0 Protein of unknown function (DUF3792) Phage_holin_3_2 PF04550.12 KXH61348.1 - 0.081 13.5 0.1 0.23 12.0 0.1 1.7 1 0 0 1 1 1 0 Phage holin family 2 CTP_synth_N PF06418.14 KXH61349.1 - 1.1e-121 405.2 0.1 1.5e-121 404.8 0.1 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 KXH61349.1 - 2e-51 174.5 0.0 3.1e-51 173.9 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KXH61349.1 - 0.0059 16.4 0.0 0.023 14.4 0.0 2.0 1 1 0 1 1 1 1 Peptidase C26 TPP_enzyme_M_2 PF16582.5 KXH61349.1 - 0.016 15.0 0.0 0.026 14.2 0.0 1.3 1 0 0 1 1 1 0 Middle domain of thiamine pyrophosphate CbiA PF01656.23 KXH61349.1 - 0.11 12.5 0.0 0.66 10.0 0.0 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Frankia_peptide PF14407.6 KXH61350.1 - 0.12 12.3 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. ARID PF01388.21 KXH61351.1 - 2.9e-19 69.5 0.4 1e-18 67.7 0.0 2.2 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain CDC73_N PF16050.5 KXH61351.1 - 0.35 10.1 5.6 0.035 13.4 0.5 1.8 2 0 0 2 2 2 0 Paf1 complex subunit CDC73 N-terminal Img2 PF05046.14 KXH61352.1 - 9.2e-22 77.1 0.0 1.2e-21 76.7 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) SUI1 PF01253.22 KXH61352.1 - 0.032 14.8 0.0 0.048 14.2 0.0 1.3 1 0 0 1 1 1 0 Translation initiation factor SUI1 Poly_export PF02563.16 KXH61352.1 - 0.032 14.4 0.0 2.8 8.2 0.0 2.2 2 0 0 2 2 2 0 Polysaccharide biosynthesis/export protein eIF3_N PF09440.10 KXH61353.1 - 1.2e-44 152.0 0.6 4.8e-44 150.0 0.2 2.2 2 0 0 2 2 2 1 eIF3 subunit 6 N terminal domain PCI PF01399.27 KXH61353.1 - 1.2e-13 51.5 0.0 3.8e-13 49.9 0.0 1.9 1 0 0 1 1 1 1 PCI domain RPN7 PF10602.9 KXH61353.1 - 0.014 15.1 0.1 0.046 13.4 0.1 1.8 2 0 0 2 2 2 0 26S proteasome subunit RPN7 TPR_14 PF13428.6 KXH61353.1 - 0.48 11.4 3.4 6.3 7.9 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC1 PF12859.7 KXH61354.1 - 1.6e-41 141.9 0.4 5e-41 140.3 0.4 1.9 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.22 KXH61354.1 - 0.64 10.6 8.2 2.4 8.7 0.2 4.4 5 0 0 5 5 5 0 Proteasome/cyclosome repeat Clathrin PF00637.20 KXH61355.1 - 2.5e-19 69.6 3.5 2.5e-19 69.6 3.5 2.4 2 1 0 2 2 2 1 Region in Clathrin and VPS BUD22 PF09073.10 KXH61355.1 - 0.00036 20.0 13.9 0.00036 20.0 13.9 2.2 2 0 0 2 2 2 1 BUD22 YL1 PF05764.13 KXH61355.1 - 0.0024 18.0 10.6 0.0059 16.8 10.6 1.7 1 0 0 1 1 1 1 YL1 nuclear protein Vps39_1 PF10366.9 KXH61355.1 - 0.0036 17.5 0.6 0.011 15.9 0.6 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 1 NBP1 PF08537.10 KXH61355.1 - 0.0097 15.4 1.9 0.017 14.5 1.9 1.3 1 0 0 1 1 1 1 Fungal Nap binding protein NBP1 CDC45 PF02724.14 KXH61355.1 - 0.01 14.2 11.8 0.021 13.1 11.8 1.5 1 0 0 1 1 1 0 CDC45-like protein zf-RING_5 PF14634.6 KXH61355.1 - 0.015 15.3 3.8 0.037 14.0 3.8 1.7 1 1 0 1 1 1 0 zinc-RING finger domain WD40_like PF17005.5 KXH61355.1 - 0.017 14.5 0.0 0.036 13.4 0.0 1.5 2 0 0 2 2 2 0 WD40-like domain WD40 PF00400.32 KXH61355.1 - 0.078 13.9 0.8 15 6.7 0.0 3.8 3 0 0 3 3 3 0 WD domain, G-beta repeat Tom6 PF17112.5 KXH61355.1 - 0.082 12.4 0.0 0.22 11.0 0.0 1.7 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom6, fungal zf-RING_2 PF13639.6 KXH61355.1 - 0.26 11.6 2.9 0.28 11.6 0.6 2.1 2 0 0 2 2 2 0 Ring finger domain Mpp10 PF04006.12 KXH61355.1 - 0.27 9.6 20.8 0.51 8.7 20.8 1.3 1 0 0 1 1 1 0 Mpp10 protein DUF913 PF06025.12 KXH61355.1 - 0.27 10.1 2.7 0.55 9.1 2.7 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) SpoIIIAH PF12685.7 KXH61355.1 - 0.32 10.8 7.8 0.24 11.2 5.3 2.0 2 0 0 2 2 2 0 SpoIIIAH-like protein DNA_pol_phi PF04931.13 KXH61355.1 - 0.51 8.4 37.3 0.99 7.4 37.3 1.3 1 0 0 1 1 1 0 DNA polymerase phi zf-RING_11 PF17123.5 KXH61355.1 - 0.66 9.8 4.3 1.4 8.8 4.3 1.6 1 0 0 1 1 1 0 RING-like zinc finger SAPS PF04499.15 KXH61355.1 - 1.2 7.9 10.9 3.9 6.1 10.3 1.9 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein zf-RING_UBOX PF13445.6 KXH61355.1 - 1.6 8.8 5.1 0.14 12.2 0.2 1.8 2 0 0 2 2 1 0 RING-type zinc-finger Pox_Ag35 PF03286.14 KXH61355.1 - 9.4 6.0 17.8 32 4.2 16.8 2.2 2 0 0 2 2 2 0 Pox virus Ag35 surface protein DUF1180 PF06679.12 KXH61357.1 - 0.17 12.3 2.1 0.2 12.1 2.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) GatB_N PF02934.15 KXH61359.1 - 5.8e-100 334.2 0.0 2.2e-99 332.3 0.0 1.8 2 0 0 2 2 2 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 KXH61359.1 - 1.9e-08 34.3 1.0 3.4e-08 33.5 0.0 1.8 2 0 0 2 2 2 1 GatB domain DnaJ PF00226.31 KXH61360.1 - 7.9e-08 32.3 0.7 7.9e-08 32.3 0.7 2.3 3 0 0 3 3 3 1 DnaJ domain Spc110_C PF18520.1 KXH61360.1 - 0.092 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Spindle pole body component 110 C-terminal domain Pex14_N PF04695.13 KXH61360.1 - 0.14 12.9 6.5 0.14 12.8 0.2 2.7 2 1 1 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DEAD PF00270.29 KXH61361.1 - 5.6e-43 146.7 0.0 8.3e-43 146.2 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXH61361.1 - 7.4e-28 97.1 0.6 7.2e-27 93.9 0.3 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXH61361.1 - 0.00098 19.2 0.0 0.0017 18.4 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 KXH61361.1 - 0.093 12.1 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit AAA_16 PF13191.6 KXH61362.1 - 4.2e-10 40.3 1.5 0.00082 19.8 0.0 4.6 5 0 0 5 5 5 3 AAA ATPase domain NACHT PF05729.12 KXH61362.1 - 2.6e-08 34.0 0.2 6.6e-05 22.9 0.0 4.1 3 1 0 3 3 3 1 NACHT domain AAA_22 PF13401.6 KXH61362.1 - 2.9e-06 27.6 0.0 0.004 17.4 0.0 4.3 4 0 0 4 4 4 1 AAA domain SesA PF17107.5 KXH61362.1 - 0.0015 18.8 2.0 0.04 14.1 2.9 2.8 2 0 0 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases ABC_tran PF00005.27 KXH61362.1 - 0.0083 16.6 1.1 0.082 13.4 0.0 2.5 2 0 0 2 2 2 1 ABC transporter AAA PF00004.29 KXH61362.1 - 0.0089 16.5 0.0 13 6.2 0.0 3.6 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) BLOC1_2 PF10046.9 KXH61362.1 - 0.012 15.8 0.6 4.2 7.8 0.1 3.1 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 NB-ARC PF00931.22 KXH61362.1 - 0.015 14.5 0.0 0.056 12.6 0.0 1.9 1 0 0 1 1 1 0 NB-ARC domain APS_kinase PF01583.20 KXH61362.1 - 0.016 15.1 0.0 0.2 11.5 0.0 2.4 2 0 0 2 2 2 0 Adenylylsulphate kinase RNA_helicase PF00910.22 KXH61362.1 - 0.017 15.5 0.0 0.057 13.8 0.0 1.9 1 0 0 1 1 1 0 RNA helicase DUF5100 PF17029.5 KXH61362.1 - 0.018 14.9 0.5 0.037 13.9 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5100) ATPase_2 PF01637.18 KXH61362.1 - 0.04 13.8 0.0 5.8 6.8 0.0 3.2 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea DUF4795 PF16043.5 KXH61362.1 - 0.12 12.0 1.0 8.1 6.0 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) AAA_18 PF13238.6 KXH61362.1 - 0.14 12.7 0.0 1 9.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 KXH61362.1 - 0.14 12.5 0.0 12 6.2 0.0 3.2 2 1 0 2 2 2 0 AAA domain Syntaxin PF00804.25 KXH61362.1 - 0.2 11.3 5.1 0.64 9.6 3.3 2.4 2 0 0 2 2 2 0 Syntaxin AAA_23 PF13476.6 KXH61362.1 - 0.52 10.8 3.2 64 4.0 4.0 3.3 3 0 0 3 3 3 0 AAA domain LrgB PF04172.16 KXH61364.1 - 6.2e-55 186.0 9.0 6.2e-55 186.0 9.0 2.4 2 0 0 2 2 2 1 LrgB-like family LrgA PF03788.14 KXH61364.1 - 0.011 15.7 10.3 0.011 15.7 10.3 3.7 4 1 1 5 5 5 0 LrgA family DUF1614 PF07758.11 KXH61364.1 - 1.9 8.5 22.9 0.3 11.1 1.2 4.0 3 1 1 4 4 4 0 Protein of unknown function (DUF1614) COesterase PF00135.28 KXH61365.1 - 4.8e-73 246.8 0.0 1.5e-72 245.2 0.0 1.6 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXH61365.1 - 0.0022 17.9 2.7 0.0087 15.9 2.7 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF1752 PF08550.10 KXH61374.1 - 1.6e-12 47.0 0.4 3e-12 46.2 0.4 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Med3 PF11593.8 KXH61374.1 - 0.21 10.7 15.5 0.34 10.1 15.5 1.6 1 1 0 1 1 1 0 Mediator complex subunit 3 fungal Spt20 PF12090.8 KXH61374.1 - 2.4 7.7 16.1 0.25 10.9 11.6 1.5 2 0 0 2 2 2 0 Spt20 family tRNA_int_end_N2 PF12928.7 KXH61389.1 - 8.1e-20 70.8 0.3 1.6e-19 69.9 0.3 1.5 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term G6PD_bact PF10786.9 KXH61389.1 - 0.013 15.0 0.8 0.47 10.0 0.1 2.1 2 0 0 2 2 2 0 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) tRNA_int_endo_N PF02778.14 KXH61389.1 - 0.05 13.3 0.0 0.16 11.7 0.2 1.7 2 0 0 2 2 2 0 tRNA intron endonuclease, N-terminal domain DUF3437 PF11919.8 KXH61389.1 - 0.15 12.0 0.1 12 5.9 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3437) Epimerase PF01370.21 KXH61392.1 - 3.5e-21 75.8 0.0 4.8e-21 75.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXH61392.1 - 4.5e-14 52.1 0.0 6.7e-14 51.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KXH61392.1 - 3.9e-11 42.6 0.0 1e-10 41.2 0.0 1.6 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 KXH61392.1 - 1.1e-10 41.7 0.1 1.6e-10 41.2 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KXH61392.1 - 4.5e-09 36.2 0.0 6.7e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KXH61392.1 - 2.3e-07 30.3 0.0 3.9e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 KXH61392.1 - 2.4e-06 27.6 0.1 4e-06 26.9 0.1 1.3 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 KXH61392.1 - 0.00012 21.7 0.0 0.00054 19.5 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase F420_oxidored PF03807.17 KXH61392.1 - 0.0028 18.2 0.0 0.012 16.2 0.0 2.1 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent RmlD_sub_bind PF04321.17 KXH61392.1 - 0.0045 16.1 0.1 0.014 14.5 0.1 2.1 1 1 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.13 KXH61392.1 - 0.013 15.0 0.3 0.034 13.7 0.2 1.9 2 1 0 2 2 2 0 NmrA-like family adh_short_C2 PF13561.6 KXH61392.1 - 0.033 13.7 0.3 0.068 12.7 0.3 1.5 1 1 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Glyco_trans_4_4 PF13579.6 KXH61392.1 - 0.061 13.8 0.9 0.18 12.2 0.9 1.9 1 1 0 1 1 1 0 Glycosyl transferase 4-like domain Flg_hook PF02120.16 KXH61392.1 - 0.077 12.9 0.0 0.27 11.1 0.0 1.9 2 0 0 2 2 2 0 Flagellar hook-length control protein FliK GDPD PF03009.17 KXH61396.1 - 1.9e-69 234.3 0.0 6.6e-69 232.5 0.0 1.9 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.7 KXH61396.1 - 1.4e-35 121.7 0.3 2.4e-15 56.9 0.1 4.0 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXH61396.1 - 2e-23 82.4 0.9 3.3e-07 30.7 0.1 5.6 4 1 1 5 5 5 4 Ankyrin repeats (many copies) SPX PF03105.19 KXH61396.1 - 1.4e-21 77.8 9.3 1e-10 42.1 0.1 3.8 2 1 1 4 4 4 3 SPX domain Ank_5 PF13857.6 KXH61396.1 - 1.3e-17 63.6 0.6 2.6e-06 27.6 0.0 5.6 2 2 3 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXH61396.1 - 3.7e-16 57.6 0.2 0.0073 16.7 0.0 7.3 7 0 0 7 7 7 3 Ankyrin repeat Ank PF00023.30 KXH61396.1 - 3.5e-15 55.7 1.4 0.002 18.5 0.0 6.4 6 0 0 6 6 6 3 Ankyrin repeat zf-MYND PF01753.18 KXH61398.1 - 0.0045 17.0 0.6 0.0045 17.0 0.6 1.8 2 0 0 2 2 2 1 MYND finger PPR_3 PF13812.6 KXH61398.1 - 0.028 14.5 0.0 0.21 11.7 0.0 2.2 2 0 0 2 2 2 0 Pentatricopeptide repeat domain DUF866 PF05907.13 KXH61399.1 - 2.9e-66 222.2 1.0 3.2e-66 222.0 1.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) HalOD2 PF18547.1 KXH61399.1 - 0.11 12.5 1.0 1.2 9.1 0.1 2.2 2 0 0 2 2 2 0 Halobacterial output domain 2 Zn_ribbon_SprT PF17283.2 KXH61399.1 - 0.12 12.3 2.8 3.8 7.5 0.1 2.2 2 0 0 2 2 2 0 SprT-like zinc ribbon domain Zn-ribbon_8 PF09723.10 KXH61399.1 - 0.13 12.4 0.4 17 5.7 0.0 2.5 2 0 0 2 2 2 0 Zinc ribbon domain DUF4379 PF14311.6 KXH61399.1 - 0.61 10.5 5.9 0.19 12.1 1.5 2.3 1 1 1 2 2 2 0 Probable Zinc-ribbon domain Metallophos PF00149.28 KXH61400.1 - 1.3e-31 110.7 0.0 2.4e-27 96.8 0.0 2.5 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Glyco_hydro_65N PF03636.15 KXH61400.1 - 0.053 13.1 0.0 0.092 12.4 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain Smg4_UPF3 PF03467.15 KXH61401.1 - 1.7e-48 164.9 0.0 1.7e-48 164.9 0.0 3.8 4 0 0 4 4 4 1 Smg-4/UPF3 family RRM_1 PF00076.22 KXH61401.1 - 3.3e-07 30.0 0.1 9.4e-05 22.2 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HalX PF08663.10 KXH61403.1 - 0.057 13.7 3.2 0.092 13.1 2.4 1.8 1 1 0 1 1 1 0 HalX domain VPS38 PF17649.1 KXH61403.1 - 0.13 11.2 2.5 0.17 10.8 2.5 1.2 1 0 0 1 1 1 0 Vacuolar protein sorting 38 YabA PF06156.13 KXH61403.1 - 0.18 12.5 6.6 0.59 10.8 6.6 2.0 1 1 0 1 1 1 0 Initiation control protein YabA ZapB PF06005.12 KXH61403.1 - 0.87 10.1 15.3 0.25 11.8 8.5 2.6 2 1 0 2 2 2 0 Cell division protein ZapB HALZ PF02183.18 KXH61403.1 - 9.5 6.5 9.8 7.6 6.8 1.4 2.7 1 1 1 2 2 2 0 Homeobox associated leucine zipper KASH_CCD PF14662.6 KXH61404.1 - 0.00011 22.1 9.5 0.0032 17.3 0.4 3.0 2 1 1 3 3 3 2 Coiled-coil region of CCDC155 or KASH ADIP PF11559.8 KXH61404.1 - 0.0017 18.4 3.8 0.0017 18.4 3.8 2.1 2 0 0 2 2 2 1 Afadin- and alpha -actinin-Binding ZapB PF06005.12 KXH61404.1 - 0.02 15.3 14.6 5.5 7.5 0.4 3.1 2 1 0 2 2 2 0 Cell division protein ZapB GAS PF13851.6 KXH61404.1 - 0.094 12.1 8.9 1.7 8.0 0.2 2.6 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding ATG16 PF08614.11 KXH61404.1 - 0.13 12.4 9.3 0.035 14.3 3.0 2.1 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Effector_1 PF04518.12 KXH61404.1 - 0.25 10.4 0.2 0.34 10.0 0.2 1.1 1 0 0 1 1 1 0 Effector from type III secretion system XRCC4 PF06632.12 KXH61404.1 - 0.29 9.9 2.1 7 5.4 0.1 2.3 1 1 1 2 2 2 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 PRKG1_interact PF15898.5 KXH61404.1 - 0.48 11.3 9.6 5 8.1 0.0 3.9 3 1 1 4 4 4 0 cGMP-dependent protein kinase interacting domain YabA PF06156.13 KXH61404.1 - 0.72 10.5 6.5 8.5 7.1 0.7 3.2 1 1 2 3 3 3 0 Initiation control protein YabA NYD-SP28_assoc PF14775.6 KXH61404.1 - 0.82 9.8 9.0 2.9 8.1 0.1 3.9 4 0 0 4 4 4 0 Sperm tail C-terminal domain SMP PF04927.12 KXH61406.1 - 0.0038 17.7 2.1 0.0041 17.6 0.1 2.0 1 1 1 2 2 2 1 Seed maturation protein Thr_synth_N PF14821.6 KXH61407.1 - 1.5e-27 95.6 0.0 3.4e-27 94.5 0.0 1.7 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.25 KXH61407.1 - 1.4e-19 70.7 0.0 1.6e-18 67.2 0.0 2.0 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme AT_hook PF02178.19 KXH61408.1 - 2.1 8.5 27.2 0.13 12.2 3.8 3.7 3 0 0 3 3 3 0 AT hook motif RTP1_C1 PF10363.9 KXH61409.1 - 1.1e-24 86.7 2.8 1.8e-24 86.1 0.2 2.7 3 1 1 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 RTP1_C2 PF10304.9 KXH61409.1 - 7.6e-15 54.3 0.8 2.1e-14 52.8 0.8 1.8 1 0 0 1 1 1 1 Required for nuclear transport of RNA pol II C-terminus 2 Adaptin_N PF01602.20 KXH61409.1 - 0.0097 14.5 0.1 0.021 13.4 0.1 1.5 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KXH61409.1 - 0.04 14.0 0.7 1.2 9.2 0.0 2.9 2 1 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 RNA_pol_Rpc82 PF05645.13 KXH61409.1 - 0.058 13.1 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 DNA_alkylation PF08713.11 KXH61409.1 - 0.071 12.8 0.0 0.32 10.7 0.0 2.0 2 0 0 2 2 2 0 DNA alkylation repair enzyme DUF3361 PF11841.8 KXH61409.1 - 6.4 6.7 6.1 5.7 6.9 0.1 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF3361) DUF2183 PF09949.9 KXH61411.1 - 3e-22 78.8 0.1 6.9e-22 77.7 0.1 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) adh_short_C2 PF13561.6 KXH61431.1 - 7.5e-18 64.9 0.1 8.1e-18 64.8 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXH61431.1 - 1.2e-16 60.8 0.1 1.2e-16 60.7 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase Pkinase PF00069.25 KXH61442.1 - 8.2e-50 169.6 0.0 1.2e-49 169.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXH61442.1 - 2.5e-27 95.8 0.0 3.3e-27 95.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXH61442.1 - 0.00045 19.6 0.0 0.00092 18.6 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KXH61442.1 - 0.021 14.2 0.0 0.038 13.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXH61442.1 - 0.084 12.8 0.1 0.72 9.7 0.0 2.4 2 1 1 3 3 3 0 Phosphotransferase enzyme family RIO1 PF01163.22 KXH61442.1 - 0.11 12.0 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 RIO1 family ADH_zinc_N PF00107.26 KXH61447.1 - 1.3e-07 31.6 0.0 4.5e-07 29.9 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KXH61447.1 - 0.00024 20.6 0.0 0.00045 19.8 0.0 1.4 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus HI0933_like PF03486.14 KXH61447.1 - 0.025 13.3 0.0 0.031 13.0 0.0 1.1 1 0 0 1 1 1 0 HI0933-like protein AlaDh_PNT_C PF01262.21 KXH61447.1 - 0.036 13.4 0.1 0.051 12.9 0.1 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 KXH61447.1 - 0.046 12.8 0.1 0.055 12.6 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Acetyltransf_7 PF13508.7 KXH61457.1 - 1.2e-05 25.6 0.0 3.7e-05 24.1 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXH61457.1 - 0.00051 20.3 0.2 0.049 13.9 0.2 3.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXH61457.1 - 0.0007 19.5 0.0 0.42 10.5 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXH61457.1 - 0.044 13.8 0.0 1.7 8.7 0.0 2.1 2 0 0 2 2 2 0 FR47-like protein Kelch_3 PF13415.6 KXH61458.1 - 6.9e-29 99.6 3.7 5.4e-07 29.7 0.0 6.3 5 1 1 6 6 6 6 Galactose oxidase, central domain Kelch_4 PF13418.6 KXH61458.1 - 9.6e-29 99.1 0.1 3.3e-12 46.2 0.0 6.2 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_6 PF13964.6 KXH61458.1 - 1.3e-15 57.0 0.0 0.00069 19.8 0.0 6.2 5 1 1 6 6 6 4 Kelch motif Kelch_1 PF01344.25 KXH61458.1 - 2e-14 52.9 0.0 0.02 14.5 0.0 6.4 6 0 0 6 6 6 4 Kelch motif Kelch_5 PF13854.6 KXH61458.1 - 2.6e-10 40.1 1.6 0.72 9.9 0.1 5.3 5 0 0 5 5 5 4 Kelch motif Kelch_2 PF07646.15 KXH61458.1 - 1.4e-08 34.3 0.3 2.5 8.2 0.0 5.2 6 0 0 6 6 6 4 Kelch motif PTP_tm PF18861.1 KXH61494.1 - 0.027 14.5 0.0 0.048 13.7 0.0 1.3 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J Spc7 PF08317.11 KXH61496.1 - 3.3e-12 45.9 183.3 0.0038 16.2 22.5 7.5 1 1 5 7 7 7 7 Spc7 kinetochore protein Rab5-bind PF09311.11 KXH61496.1 - 4e-07 29.7 147.3 2.5e-05 23.8 12.0 9.7 1 1 5 8 8 8 6 Rabaptin-like protein HMMR_N PF15905.5 KXH61496.1 - 2.2e-05 24.1 172.5 0.018 14.5 29.1 7.0 1 1 4 6 6 6 4 Hyaluronan mediated motility receptor N-terminal Tup_N PF08581.10 KXH61496.1 - 0.0016 18.7 106.7 0.019 15.2 2.7 14.6 3 2 12 16 16 16 7 Tup N-terminal FliJ PF02050.16 KXH61496.1 - 0.0097 16.1 0.9 0.0097 16.1 0.9 11.0 2 2 9 11 11 11 3 Flagellar FliJ protein Pox_A_type_inc PF04508.12 KXH61496.1 - 2.3 8.2 7.9 46 4.1 0.3 5.2 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat Lebercilin PF15619.6 KXH61496.1 - 3.7 7.2 175.2 0.22 11.1 30.6 9.1 1 1 7 8 8 8 0 Ciliary protein causing Leber congenital amaurosis disease Filament PF00038.21 KXH61496.1 - 5.3 6.5 158.8 0.79 9.2 50.6 8.4 1 1 5 7 7 7 0 Intermediate filament protein DUF3584 PF12128.8 KXH61496.1 - 5.4 4.4 186.2 0.46 7.9 62.1 4.2 1 1 3 4 4 4 0 Protein of unknown function (DUF3584) Cu_amine_oxid PF01179.20 KXH61497.1 - 9.7e-159 528.7 0.0 1.2e-158 528.4 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 KXH61497.1 - 1.3e-19 70.4 0.0 3.9e-19 68.9 0.0 1.8 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 KXH61497.1 - 2.8e-10 40.3 0.0 5.3e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain DDE_Tnp_1 PF01609.21 KXH61497.1 - 0.1 12.2 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 Transposase DDE domain AA_permease_2 PF13520.6 KXH61498.1 - 1.3e-53 182.4 47.0 1.8e-53 182.0 47.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXH61498.1 - 3.4e-21 75.4 37.8 4.6e-21 75.0 37.8 1.0 1 0 0 1 1 1 1 Amino acid permease DUF3493 PF11998.8 KXH61498.1 - 0.039 14.1 0.3 0.15 12.3 0.0 2.2 2 0 0 2 2 2 0 Low psii accumulation1 / Rep27 DUF1182 PF06681.13 KXH61498.1 - 2 8.0 11.4 0.035 13.7 1.9 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1182) AMP-binding PF00501.28 KXH61499.1 - 1.2e-70 238.2 0.0 2.1e-54 184.8 0.0 2.0 2 0 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 KXH61499.1 - 6.6e-15 55.8 0.0 1.3e-14 54.9 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Vhr1 PF04001.13 KXH61499.1 - 0.0025 18.1 0.0 0.0056 17.0 0.0 1.5 1 0 0 1 1 1 1 Transcription factor Vhr1 7TM_GPCR_Srv PF10323.9 KXH61499.1 - 0.14 11.5 0.1 0.22 10.8 0.1 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv ADH_N PF08240.12 KXH61500.1 - 1.9e-17 63.1 0.9 3.3e-17 62.4 0.9 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXH61500.1 - 1.1e-15 57.7 0.2 2.1e-15 56.9 0.1 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXH61500.1 - 7.1e-12 46.5 0.0 1.3e-11 45.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KXH61500.1 - 0.019 14.3 0.3 0.028 13.7 0.3 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain adh_short_C2 PF13561.6 KXH61501.1 - 3.4e-56 190.4 2.5 4.3e-56 190.1 2.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXH61501.1 - 3.4e-47 160.5 2.4 4.6e-47 160.0 2.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Abhydrolase_3 PF07859.13 KXH61502.1 - 1.2e-51 175.6 0.0 1.5e-51 175.2 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KXH61502.1 - 2.2e-11 43.3 0.7 1.9e-10 40.3 0.7 1.9 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 KXH61502.1 - 0.00016 21.2 0.1 0.089 12.3 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 KXH61502.1 - 0.0073 16.9 0.1 0.012 16.2 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 KXH61502.1 - 0.11 12.1 0.0 0.42 10.1 0.0 1.8 2 0 0 2 2 2 0 Dienelactone hydrolase family Chlorophyllase2 PF12740.7 KXH61502.1 - 0.11 11.3 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Pyr_redox_3 PF13738.6 KXH61503.1 - 6.4e-14 51.9 0.0 5e-13 49.0 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KXH61503.1 - 1.7e-13 49.9 0.0 3.3e-13 48.9 0.0 1.4 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KXH61503.1 - 1.5e-11 44.1 0.0 1.8e-09 37.3 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXH61503.1 - 3.4e-09 36.3 0.0 2.7e-07 30.1 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KXH61503.1 - 8.6e-08 32.1 0.2 0.001 18.7 0.1 2.9 2 1 1 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXH61503.1 - 6.3e-07 29.5 0.1 5.6e-06 26.5 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KXH61503.1 - 0.00064 18.9 0.0 0.0014 17.8 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 KXH61503.1 - 0.0017 18.4 0.1 9.2 6.2 0.0 3.8 3 1 0 3 3 3 1 FAD-NAD(P)-binding HI0933_like PF03486.14 KXH61503.1 - 0.0026 16.6 0.0 0.13 10.9 0.1 2.6 3 0 0 3 3 3 1 HI0933-like protein Thi4 PF01946.17 KXH61503.1 - 0.005 16.1 0.0 0.012 14.9 0.0 1.5 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 KXH61503.1 - 0.012 16.1 0.3 2.9 8.5 0.3 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KXH61503.1 - 0.041 13.1 0.8 1.6 7.9 0.7 2.2 1 1 1 2 2 2 0 FAD binding domain NAD_binding_7 PF13241.6 KXH61503.1 - 0.049 14.1 0.0 1.1 9.7 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding Shikimate_DH PF01488.20 KXH61503.1 - 0.087 12.9 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Lactamase_B PF00753.27 KXH61504.1 - 2.3e-09 37.5 0.0 5.2e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KXH61504.1 - 0.011 15.2 0.0 0.028 13.9 0.0 1.7 1 1 0 1 1 1 0 Beta-lactamase superfamily domain MFS_1 PF07690.16 KXH61505.1 - 1.6e-33 116.1 31.4 1.6e-33 116.1 31.4 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Na_Pi_cotrans PF02690.15 KXH61505.1 - 0.0081 16.3 4.0 0.13 12.3 0.3 2.6 2 0 0 2 2 2 2 Na+/Pi-cotransporter Fungal_trans PF04082.18 KXH61506.1 - 3.8e-12 45.8 0.3 6.1e-12 45.1 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH61506.1 - 1.2e-05 25.3 8.0 2.1e-05 24.5 8.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Elf1 PF05129.13 KXH61506.1 - 0.42 10.7 3.7 0.83 9.7 3.7 1.4 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like FMO-like PF00743.19 KXH61507.1 - 4.3e-16 58.4 0.0 1.2e-15 56.9 0.0 1.7 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KXH61507.1 - 6.8e-10 39.0 0.0 2.7e-09 37.1 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KXH61507.1 - 9.1e-08 31.7 0.0 7.5e-06 25.4 0.0 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXH61507.1 - 1.1e-05 24.8 0.0 0.0039 16.5 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXH61507.1 - 3.5e-05 23.1 0.0 0.0005 19.3 0.0 2.5 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KXH61507.1 - 0.0016 18.5 0.3 0.1 12.6 0.0 3.2 3 0 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.24 KXH61507.1 - 0.017 14.7 0.3 0.96 9.0 0.3 2.8 1 1 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.17 KXH61507.1 - 0.017 14.3 0.0 8.5 5.5 0.0 2.8 3 0 0 3 3 3 0 Thi4 family Amino_oxidase PF01593.24 KXH61507.1 - 0.081 12.2 0.1 0.59 9.4 0.0 2.4 2 2 1 3 3 3 0 Flavin containing amine oxidoreductase adh_short PF00106.25 KXH61508.1 - 1.7e-29 102.6 0.0 2.4e-29 102.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXH61508.1 - 8e-23 81.2 0.0 1.2e-22 80.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH61508.1 - 1.9e-08 34.4 0.0 3.6e-06 27.0 0.0 2.2 2 0 0 2 2 2 2 KR domain Proton_antipo_C PF01010.19 KXH61509.1 - 0.001 18.8 0.2 0.0017 18.0 0.2 1.3 1 0 0 1 1 1 1 NADH-dehyrogenase subunit F, TMs, (complex I) C-terminus CD99L2 PF12301.8 KXH61509.1 - 0.01 16.1 0.2 0.01 16.1 0.2 2.2 1 1 1 2 2 2 0 CD99 antigen like protein 2 EphA2_TM PF14575.6 KXH61510.1 - 0.003 18.4 0.0 0.0033 18.3 0.0 1.1 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Shisa PF13908.6 KXH61510.1 - 0.0059 16.9 0.1 0.0076 16.5 0.1 1.1 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Adeno_E3_CR2 PF02439.15 KXH61510.1 - 0.13 12.1 5.9 0.2 11.5 5.9 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 RCR PF12273.8 KXH61510.1 - 0.13 12.9 1.8 0.26 11.9 1.8 1.7 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red Sugar_tr PF00083.24 KXH61511.1 - 7.5e-101 338.2 14.1 8.6e-101 338.0 14.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH61511.1 - 3.6e-34 118.3 29.0 5.4e-25 88.1 11.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KXH61511.1 - 3.3e-09 35.8 10.5 2.7e-06 26.2 0.6 2.4 2 1 0 2 2 2 2 MFS/sugar transport protein Alpha-L-AF_C PF06964.12 KXH61512.1 - 9.1e-31 107.2 0.1 1.5e-30 106.6 0.1 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain Glyco_hydro_47 PF01532.20 KXH61513.1 - 1.9e-173 577.6 0.0 2.2e-173 577.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 ABC_tran PF00005.27 KXH61520.1 - 7e-33 114.0 0.0 1.8e-32 112.7 0.0 1.7 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 KXH61520.1 - 7.8e-24 84.8 3.2 7.8e-24 84.8 3.2 2.2 3 0 0 3 3 3 1 ABC transporter transmembrane region SMC_N PF02463.19 KXH61520.1 - 4.4e-05 23.0 0.0 0.00016 21.2 0.0 1.7 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain PAM2 PF07145.15 KXH61520.1 - 0.00074 19.0 0.2 0.024 14.3 0.1 2.5 2 0 0 2 2 2 1 Ataxin-2 C-terminal region RsgA_GTPase PF03193.16 KXH61520.1 - 0.0051 16.7 0.1 0.011 15.7 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase T2SSE PF00437.20 KXH61520.1 - 0.0081 15.3 0.0 0.17 10.9 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_30 PF13604.6 KXH61520.1 - 0.036 13.8 0.0 0.092 12.5 0.0 1.6 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KXH61520.1 - 0.045 13.0 0.3 0.17 11.2 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin AAA_29 PF13555.6 KXH61520.1 - 0.11 12.3 0.3 0.32 10.8 0.3 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_15 PF13175.6 KXH61520.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain MTABC_N PF16185.5 KXH61520.1 - 6.1 6.3 11.6 4 6.8 0.1 3.4 3 0 0 3 3 3 0 Mitochondrial ABC-transporter N-terminal five TM region SGTA_dimer PF16546.5 KXH61521.1 - 9.2e-25 86.2 0.5 2e-24 85.1 0.5 1.6 1 0 0 1 1 1 1 Homodimerisation domain of SGTA TPR_1 PF00515.28 KXH61521.1 - 1.1e-15 56.6 4.7 7.8e-07 28.7 0.3 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KXH61521.1 - 1.2e-13 50.0 7.4 7.1e-06 25.8 0.2 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 KXH61521.1 - 4.8e-09 35.8 3.2 3.9e-05 23.3 0.6 3.2 2 1 1 3 3 3 3 TPR repeat TPR_8 PF13181.6 KXH61521.1 - 1.6e-08 34.1 3.4 0.17 12.2 0.0 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 KXH61521.1 - 1.7e-07 31.8 31.4 7.3e-05 23.3 2.0 2.9 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 KXH61521.1 - 4e-06 26.8 2.6 0.0011 19.2 0.4 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KXH61521.1 - 0.00021 21.8 14.1 0.084 13.7 0.1 4.3 2 1 3 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 KXH61521.1 - 0.00025 21.5 0.8 0.00025 21.5 0.8 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 KXH61521.1 - 0.0008 19.3 0.2 0.33 11.1 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 KXH61521.1 - 0.0012 18.9 1.4 0.036 14.2 0.7 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat STI1 PF17830.1 KXH61521.1 - 0.0015 18.5 13.6 0.0018 18.2 8.8 2.4 2 0 0 2 2 2 1 STI1 domain TPR_12 PF13424.6 KXH61521.1 - 0.0026 18.0 7.4 0.0074 16.6 2.6 3.1 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 KXH61521.1 - 0.041 13.8 4.1 0.76 9.7 0.3 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat BTAD PF03704.17 KXH61521.1 - 0.16 12.4 9.1 0.29 11.6 1.1 2.8 1 1 2 3 3 3 0 Bacterial transcriptional activator domain XPC-binding PF09280.11 KXH61521.1 - 0.33 10.7 4.5 0.26 11.1 2.8 1.7 2 0 0 2 2 2 0 XPC-binding domain TPR_6 PF13174.6 KXH61521.1 - 1.9 9.3 5.5 3 8.7 0.3 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat adh_short PF00106.25 KXH61536.1 - 9.2e-41 139.5 3.3 1.2e-40 139.1 3.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXH61536.1 - 1.4e-34 119.7 2.5 1.9e-34 119.2 2.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH61536.1 - 3.5e-14 53.1 1.8 5.2e-14 52.6 1.8 1.2 1 0 0 1 1 1 1 KR domain Gpi1 PF05024.15 KXH61549.1 - 4.6e-77 258.3 8.5 8.2e-77 257.5 8.5 1.4 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) UPF0203 PF05254.12 KXH61549.1 - 2.8e-25 88.3 2.5 6e-25 87.3 2.5 1.6 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) 7tm_1 PF00001.21 KXH61549.1 - 0.004 16.5 0.8 0.004 16.5 0.8 1.9 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) COX17 PF05051.13 KXH61549.1 - 0.0073 16.6 0.4 0.015 15.6 0.4 1.5 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.10 KXH61549.1 - 0.34 11.0 3.1 1.2 9.2 0.1 2.5 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like DNA_pol_A_exo1 PF01612.20 KXH61550.1 - 1.6e-40 138.6 0.3 2.6e-40 138.0 0.3 1.3 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.12 KXH61550.1 - 1.5e-23 83.3 0.4 1.5e-23 83.3 0.4 2.4 2 0 0 2 2 2 1 PMC2NT (NUC016) domain HRDC PF00570.23 KXH61550.1 - 3e-11 43.2 1.2 9.5e-11 41.5 0.0 2.5 3 0 0 3 3 3 1 HRDC domain Borrelia_P83 PF05262.11 KXH61550.1 - 0.06 11.8 40.3 0.11 11.0 40.3 1.4 1 0 0 1 1 1 0 Borrelia P83/100 protein RNA_pol_3_Rpc31 PF11705.8 KXH61550.1 - 7.3 6.8 30.7 3.7 7.7 28.0 1.9 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 2-Hacid_dh_C PF02826.19 KXH61551.1 - 2e-37 128.3 0.1 2.6e-36 124.6 0.1 2.3 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KXH61551.1 - 1.6e-19 69.9 0.0 2.4e-19 69.3 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KXH61551.1 - 0.0004 20.6 1.1 0.00093 19.4 0.4 2.0 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KXH61551.1 - 0.0055 17.3 0.6 0.02 15.5 0.1 2.3 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent ADH_zinc_N PF00107.26 KXH61551.1 - 0.0078 16.2 2.2 0.024 14.6 1.5 2.1 2 1 0 2 2 2 1 Zinc-binding dehydrogenase AdoHcyase_NAD PF00670.21 KXH61551.1 - 0.017 15.2 1.7 0.75 9.8 0.7 2.7 2 1 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain XdhC_C PF13478.6 KXH61551.1 - 0.048 14.2 0.0 0.11 13.0 0.0 1.6 1 0 0 1 1 1 0 XdhC Rossmann domain IlvN PF07991.12 KXH61551.1 - 0.06 12.9 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_Gly3P_dh_N PF01210.23 KXH61551.1 - 0.064 13.2 0.1 0.13 12.3 0.1 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Sacchrp_dh_NADP PF03435.18 KXH61551.1 - 0.12 12.6 0.0 0.27 11.5 0.0 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Methyltransf_23 PF13489.6 KXH61553.1 - 6.7e-20 71.6 0.0 1e-19 70.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH61553.1 - 3.4e-10 40.5 0.0 7.1e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH61553.1 - 3.9e-08 33.8 0.0 7.3e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH61553.1 - 9.4e-08 32.0 0.0 1e-06 28.6 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH61553.1 - 1e-07 32.6 0.0 6.9e-07 29.9 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXH61553.1 - 0.0092 15.5 0.0 0.018 14.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 KXH61553.1 - 0.012 14.9 0.0 0.025 13.9 0.0 1.4 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase PrmA PF06325.13 KXH61553.1 - 0.1 12.0 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DUF3120 PF11318.8 KXH61554.1 - 0.026 14.9 1.4 0.032 14.6 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3120) HpcH_HpaI PF03328.14 KXH61555.1 - 3.5e-28 98.2 0.0 4.5e-28 97.9 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PK PF00224.21 KXH61555.1 - 0.00088 18.2 0.1 0.0013 17.7 0.1 1.2 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain Aminotran_1_2 PF00155.21 KXH61556.1 - 1.4e-68 231.7 0.0 1.7e-68 231.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Methyltransf_2 PF00891.18 KXH61557.1 - 2.3e-18 66.3 0.0 3.2e-18 65.8 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain MarR_2 PF12802.7 KXH61557.1 - 6.1e-05 22.8 0.0 0.00013 21.8 0.0 1.4 1 0 0 1 1 1 1 MarR family Rrf2 PF02082.20 KXH61557.1 - 0.00048 20.4 0.0 0.00097 19.4 0.0 1.4 1 0 0 1 1 1 1 Transcriptional regulator MarR PF01047.22 KXH61557.1 - 0.0015 18.4 0.0 0.0031 17.4 0.0 1.4 1 0 0 1 1 1 1 MarR family HTH_24 PF13412.6 KXH61557.1 - 0.0018 17.8 0.0 0.0033 17.0 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_5 PF01022.20 KXH61557.1 - 0.003 17.4 0.0 0.0055 16.6 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_IclR PF09339.10 KXH61557.1 - 0.014 15.2 0.1 0.032 14.0 0.1 1.6 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_Crp_2 PF13545.6 KXH61557.1 - 0.028 14.4 0.0 0.055 13.5 0.0 1.4 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain Fe_dep_repress PF01325.19 KXH61557.1 - 0.034 14.3 0.0 0.065 13.4 0.0 1.4 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain HTH_27 PF13463.6 KXH61557.1 - 0.049 14.1 0.0 0.1 13.1 0.0 1.5 1 0 0 1 1 1 0 Winged helix DNA-binding domain HTH_6 PF01418.17 KXH61557.1 - 0.071 13.1 0.0 0.22 11.5 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain, rpiR family Dimerisation PF08100.11 KXH61557.1 - 0.082 12.9 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Dimerisation domain Phage_holin_5_2 PF16079.5 KXH61558.1 - 0.098 13.0 0.3 0.098 13.0 0.3 2.9 3 1 0 3 3 3 0 Phage holin family Hol44, in holin superfamily V MFS_1 PF07690.16 KXH61560.1 - 7.6e-14 51.4 31.9 6.5e-13 48.3 32.1 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF2929 PF11151.8 KXH61560.1 - 0.042 14.1 0.1 0.042 14.1 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2929) Sugar_tr PF00083.24 KXH61560.1 - 0.11 11.3 13.0 0.17 10.7 13.0 1.3 1 0 0 1 1 1 0 Sugar (and other) transporter MFS_2 PF13347.6 KXH61560.1 - 0.3 9.6 13.8 0.019 13.6 4.4 2.3 1 1 0 2 2 2 0 MFS/sugar transport protein Amidohydro_1 PF01979.20 KXH61561.1 - 5.9e-43 147.5 0.2 7.1e-43 147.2 0.2 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KXH61561.1 - 1.9e-21 77.1 0.1 6.6e-14 52.2 0.1 2.2 2 0 0 2 2 2 2 Amidohydrolase family DPBB_1 PF03330.18 KXH61562.1 - 2e-07 31.2 1.0 7.1e-07 29.4 0.2 2.4 2 1 0 2 2 2 1 Lytic transglycolase Pollen_allerg_1 PF01357.21 KXH61562.1 - 1.2e-05 25.2 2.2 2.8e-05 24.0 2.2 1.6 1 0 0 1 1 1 1 Pollen allergen Barwin PF00967.17 KXH61562.1 - 0.00029 20.7 0.6 0.00067 19.5 0.1 1.9 2 0 0 2 2 2 1 Barwin family Toxin_28 PF08115.11 KXH61562.1 - 0.51 10.2 11.2 0.21 11.5 3.4 2.4 2 0 0 2 2 2 0 SFI toxin family Fungal_trans PF04082.18 KXH61563.1 - 1e-18 67.4 0.1 5.6e-18 64.9 0.1 2.3 2 1 0 2 2 2 1 Fungal specific transcription factor domain AA_permease PF00324.21 KXH61564.1 - 1.3e-112 376.9 44.7 1.5e-112 376.6 44.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KXH61564.1 - 1.6e-34 119.4 44.6 2e-34 119.2 44.6 1.1 1 0 0 1 1 1 1 Amino acid permease ADH_zinc_N PF00107.26 KXH61565.1 - 1.5e-08 34.7 0.2 4e-08 33.3 0.1 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXH61565.1 - 2.7e-06 27.2 0.0 4.8e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain TMEM215 PF15746.5 KXH61565.1 - 0.063 12.7 1.4 0.17 11.3 0.6 1.8 2 0 0 2 2 2 0 TMEM215 family zf-LITAF-like PF10601.9 KXH61566.1 - 3.6e-15 56.0 16.4 5.2e-15 55.5 16.4 1.2 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain HET PF06985.11 KXH61567.1 - 3.8e-12 46.8 7.1 3.8e-10 40.3 1.8 2.8 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Ribosomal_60s PF00428.19 KXH61567.1 - 2.4 8.8 4.8 0.62 10.7 0.4 2.3 3 0 0 3 3 3 0 60s Acidic ribosomal protein Lyase_1 PF00206.20 KXH61568.1 - 4e-89 299.1 0.0 5.1e-89 298.8 0.0 1.1 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.6 KXH61568.1 - 1.6e-25 89.7 0.0 3.4e-25 88.6 0.0 1.6 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal Methyltransf_11 PF08241.12 KXH61574.1 - 2.7e-16 60.0 0.2 6.2e-16 58.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH61574.1 - 4.1e-16 59.5 0.2 8.9e-16 58.4 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXH61574.1 - 5.6e-15 55.3 0.0 2e-14 53.5 0.0 1.7 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 KXH61574.1 - 4.9e-12 45.9 0.0 7.3e-12 45.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH61574.1 - 3.6e-09 37.3 0.0 5.8e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXH61574.1 - 1e-07 31.9 0.0 1.6e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXH61574.1 - 0.001 18.7 0.1 0.0017 17.9 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_8 PF05148.15 KXH61574.1 - 0.0035 17.2 0.0 0.013 15.4 0.0 1.8 2 0 0 2 2 2 1 Hypothetical methyltransferase TehB PF03848.14 KXH61574.1 - 0.0046 16.4 0.0 0.0082 15.6 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB MetW PF07021.12 KXH61574.1 - 0.0087 15.7 0.1 0.044 13.4 0.1 1.9 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltr_RsmB-F PF01189.17 KXH61574.1 - 0.094 12.3 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F DNA_PPF PF02916.15 KXH61574.1 - 0.16 12.4 0.0 0.28 11.6 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase processivity factor PTR2 PF00854.21 KXH61576.1 - 2.2e-90 303.4 4.8 4.3e-90 302.4 4.8 1.4 1 1 0 1 1 1 1 POT family MFS_1 PF07690.16 KXH61576.1 - 1.1e-05 24.5 20.1 1.1e-05 24.5 20.1 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily adh_short_C2 PF13561.6 KXH61577.1 - 3.1e-42 144.7 0.2 2e-39 135.5 0.1 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXH61577.1 - 3.2e-40 137.7 0.0 4e-40 137.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXH61577.1 - 2.4e-12 47.2 0.1 3.4e-12 46.6 0.1 1.1 1 0 0 1 1 1 1 KR domain OB_aCoA_assoc PF01796.17 KXH61577.1 - 0.0051 16.8 0.1 0.014 15.4 0.1 1.7 1 0 0 1 1 1 1 DUF35 OB-fold domain, acyl-CoA-associated Epimerase PF01370.21 KXH61577.1 - 0.038 13.5 0.1 0.099 12.1 0.1 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Fibrillarin PF01269.17 KXH61577.1 - 0.038 13.1 0.0 0.062 12.4 0.0 1.3 1 0 0 1 1 1 0 Fibrillarin Ribosomal_L26 PF16906.5 KXH61577.1 - 0.11 13.0 0.0 0.15 12.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal proteins L26 eukaryotic, L24P archaeal Methyltransf_3 PF01596.17 KXH61579.1 - 3.9e-22 78.5 0.0 5.2e-22 78.1 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 KXH61579.1 - 1.3e-11 45.5 0.0 2.2e-11 44.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH61579.1 - 2.3e-07 31.4 0.0 5.1e-07 30.3 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH61579.1 - 9.3e-07 29.4 0.0 1.9e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH61579.1 - 6.1e-06 26.1 0.0 9.5e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.10 KXH61579.1 - 0.00075 19.1 0.0 0.00099 18.7 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Cons_hypoth95 PF03602.15 KXH61579.1 - 0.0075 15.9 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_23 PF13489.6 KXH61579.1 - 0.016 15.0 0.0 0.024 14.5 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 KXH61579.1 - 0.096 12.4 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MARVEL PF01284.23 KXH61580.1 - 6.8e-07 29.4 13.3 6.1e-06 26.3 13.3 1.9 1 1 0 1 1 1 1 Membrane-associating domain VIT1 PF01988.19 KXH61580.1 - 0.32 10.8 2.9 0.45 10.3 2.9 1.3 1 0 0 1 1 1 0 VIT family Spo7 PF03907.13 KXH61580.1 - 0.49 9.8 2.3 0.54 9.7 1.4 1.4 2 0 0 2 2 2 0 Spo7-like protein Abhydrolase_1 PF00561.20 KXH61581.1 - 4.9e-14 52.6 0.0 9.8e-14 51.6 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXH61581.1 - 1.5e-10 42.1 0.0 1.9e-10 41.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXH61581.1 - 5.9e-09 35.5 0.0 9e-09 34.9 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 KXH61581.1 - 0.025 14.7 0.0 0.047 13.8 0.0 1.4 1 1 0 1 1 1 0 Thioesterase domain Abhydrolase_3 PF07859.13 KXH61581.1 - 0.037 13.9 0.0 0.057 13.3 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF2048 PF09752.9 KXH61581.1 - 0.059 12.5 0.0 0.085 11.9 0.0 1.2 1 0 0 1 1 1 0 Abhydrolase domain containing 18 Esterase PF00756.20 KXH61581.1 - 0.069 12.8 0.0 0.11 12.2 0.0 1.4 1 1 0 1 1 1 0 Putative esterase Methyltransf_24 PF13578.6 KXH61583.1 - 9.4e-15 55.5 0.0 1.6e-14 54.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.17 KXH61583.1 - 9.9e-08 31.4 0.0 1.4e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Sugar_tr PF00083.24 KXH61584.1 - 1.3e-86 291.3 21.1 1.5e-86 291.1 21.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH61584.1 - 5.1e-25 88.2 24.5 5.1e-25 88.2 24.5 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 KXH61584.1 - 0.012 14.0 0.5 0.012 14.0 0.5 2.7 2 1 1 3 3 3 0 Transmembrane secretion effector TRI12 PF06609.13 KXH61584.1 - 0.77 8.1 10.3 0.062 11.7 3.2 2.0 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) FAD_binding_3 PF01494.19 KXH61585.1 - 9.8e-13 48.1 0.7 4.1e-09 36.2 0.1 2.5 2 1 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 KXH61585.1 - 3.6e-07 29.7 0.1 0.0006 19.1 0.0 2.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXH61585.1 - 9.5e-06 25.8 0.0 3e-05 24.2 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KXH61585.1 - 1.5e-05 24.3 0.0 3.3e-05 23.2 0.0 1.5 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 KXH61585.1 - 4.1e-05 23.3 0.0 0.003 17.2 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KXH61585.1 - 4.5e-05 22.3 0.0 0.0034 16.1 0.0 2.2 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 KXH61585.1 - 0.00024 20.3 0.0 0.00061 19.0 0.0 1.6 1 1 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 KXH61585.1 - 0.0009 18.6 0.0 0.14 11.4 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KXH61585.1 - 0.0044 15.9 0.1 0.62 8.8 0.0 2.5 3 0 0 3 3 3 2 Tryptophan halogenase Pyr_redox PF00070.27 KXH61585.1 - 0.0051 17.3 0.0 0.068 13.7 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KXH61585.1 - 0.0096 15.3 0.0 1.4 8.1 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 KXH61585.1 - 0.02 14.3 0.0 0.036 13.4 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 KXH61585.1 - 0.13 11.5 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DUF4870 PF09685.10 KXH61586.1 - 1.8 8.7 11.1 0.12 12.4 3.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4870) Pectate_lyase PF03211.13 KXH61587.1 - 1.1e-78 263.5 8.3 1.2e-78 263.3 8.3 1.0 1 0 0 1 1 1 1 Pectate lyase Glyco_hydro_79C PF16862.5 KXH61588.1 - 5.6e-18 65.7 3.8 1.2e-17 64.7 0.7 2.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 79 C-terminal beta domain CDO_I PF05995.12 KXH61588.1 - 0.14 11.5 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 Cysteine dioxygenase type I Secretin_N_2 PF07655.13 KXH61588.1 - 4.2 8.0 9.8 13 6.4 9.8 1.7 1 0 0 1 1 1 0 Secretin N-terminal domain SR-25 PF10500.9 KXH61589.1 - 0.001 18.7 8.3 0.0011 18.7 8.3 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein AP3D1 PF06375.11 KXH61589.1 - 0.0089 16.3 8.6 0.011 16.0 8.6 1.2 1 0 0 1 1 1 1 AP-3 complex subunit delta-1 SPT6_acidic PF14632.6 KXH61589.1 - 0.08 13.5 6.2 0.13 12.8 6.2 1.3 1 0 0 1 1 1 0 Acidic N-terminal SPT6 Protocadherin PF08374.11 KXH61589.1 - 0.29 11.1 5.5 0.41 10.6 5.5 1.2 1 0 0 1 1 1 0 Protocadherin Med19 PF10278.9 KXH61589.1 - 0.82 9.6 13.4 1.1 9.1 13.4 1.1 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Peptidase_S49_N PF08496.10 KXH61589.1 - 0.93 9.5 8.6 1.4 9.0 8.6 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal OAD_gamma PF04277.13 KXH61589.1 - 4.1 8.1 4.7 6.6 7.4 4.7 1.3 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Cutinase PF01083.22 KXH61590.1 - 2e-25 89.8 1.2 2.9e-25 89.2 1.2 1.3 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 KXH61590.1 - 0.17 11.4 0.1 0.27 10.8 0.1 1.2 1 0 0 1 1 1 0 PE-PPE domain PAP2 PF01569.21 KXH61591.1 - 1.1e-23 83.5 4.4 1.1e-23 83.5 4.4 1.9 3 0 0 3 3 3 1 PAP2 superfamily PAP2_3 PF14378.6 KXH61591.1 - 0.01 15.5 6.4 0.057 13.1 5.7 2.2 1 1 0 1 1 1 0 PAP2 superfamily DUF4231 PF14015.6 KXH61591.1 - 0.075 13.5 0.4 0.075 13.5 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) Mobilization_B PF17511.2 KXH61591.1 - 0.49 10.7 2.2 1.1 9.7 2.2 1.6 1 0 0 1 1 1 0 Mobilization protein B GMC_oxred_N PF00732.19 KXH61593.1 - 3.2e-61 207.3 0.4 5.9e-61 206.4 0.2 1.5 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXH61593.1 - 2.2e-33 115.8 0.3 4.5e-33 114.8 0.3 1.6 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KXH61593.1 - 7.4e-07 28.6 0.0 0.00097 18.3 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 KXH61593.1 - 0.00018 21.2 0.1 0.013 15.1 0.0 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXH61593.1 - 0.00024 21.3 0.5 0.0016 18.7 0.1 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXH61593.1 - 0.00049 19.4 1.3 0.1 11.8 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KXH61593.1 - 0.00078 18.6 0.6 0.0013 17.8 0.0 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.17 KXH61593.1 - 0.003 16.8 1.8 0.014 14.7 0.1 2.1 2 0 0 2 2 2 1 Thi4 family Pyr_redox_3 PF13738.6 KXH61593.1 - 0.008 15.5 0.0 3.8 6.7 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXH61593.1 - 0.035 14.7 0.6 0.92 10.1 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 KXH61593.1 - 0.053 13.8 0.4 0.23 11.7 0.1 2.1 2 0 0 2 2 2 0 TrkA-N domain HI0933_like PF03486.14 KXH61593.1 - 0.089 11.5 0.0 0.15 10.7 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Glyco_hydro_31 PF01055.26 KXH61594.1 - 6.6e-113 378.2 5.1 1e-112 377.6 5.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 KXH61594.1 - 0.0001 22.6 0.7 0.00056 20.2 0.1 2.5 2 1 0 2 2 2 1 Galactose mutarotase-like MFS_1 PF07690.16 KXH61595.1 - 3.6e-40 138.0 46.9 3.6e-40 138.0 46.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH61595.1 - 0.00039 19.4 19.9 0.00039 19.4 19.9 2.7 2 1 0 2 2 2 1 Sugar (and other) transporter DUF1269 PF06897.12 KXH61595.1 - 0.044 14.1 0.3 0.41 11.0 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1269) adh_short_C2 PF13561.6 KXH61596.1 - 3.3e-61 206.8 3.1 5e-61 206.2 3.1 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXH61596.1 - 9.7e-47 159.0 2.0 1.7e-46 158.2 2.0 1.3 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXH61596.1 - 6.6e-10 39.2 0.7 3.1e-09 37.0 0.7 1.9 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KXH61596.1 - 5.1e-06 25.8 0.3 1.3e-05 24.5 0.1 1.7 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KXH61596.1 - 0.00074 19.1 0.9 0.0018 17.7 0.9 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXH61596.1 - 0.078 12.0 0.1 0.12 11.3 0.1 1.5 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family FMO-like PF00743.19 KXH61597.1 - 2.6e-19 69.0 0.2 6.3e-18 64.5 0.0 2.3 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KXH61597.1 - 2.5e-11 43.6 0.0 4.6e-08 33.2 0.0 2.9 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KXH61597.1 - 2.9e-08 33.3 0.0 1.1e-05 24.8 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KXH61597.1 - 2.1e-07 30.5 0.0 1.1e-05 24.8 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXH61597.1 - 1.9e-06 27.4 0.0 0.0002 20.7 0.0 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXH61597.1 - 2.3e-05 23.8 0.0 0.016 14.4 0.0 2.8 3 0 0 3 3 3 2 Thi4 family DAO PF01266.24 KXH61597.1 - 0.00046 19.9 0.0 0.069 12.7 0.0 3.4 3 1 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KXH61597.1 - 0.00071 19.6 0.0 0.29 11.1 0.0 3.3 4 0 0 4 4 4 1 FAD-NAD(P)-binding 2-Hacid_dh_C PF02826.19 KXH61597.1 - 0.0093 15.3 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KXH61597.1 - 0.011 15.8 0.0 0.068 13.2 0.0 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Semialdhyde_dh PF01118.24 KXH61597.1 - 0.018 15.5 0.0 0.12 12.9 0.0 2.4 3 0 0 3 3 3 0 Semialdehyde dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 KXH61597.1 - 0.044 12.9 0.0 0.071 12.2 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 KXH61597.1 - 0.066 12.2 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein AA_permease PF00324.21 KXH61598.1 - 2e-108 363.0 47.5 2.6e-108 362.7 47.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KXH61598.1 - 1.4e-22 80.1 52.2 1.9e-22 79.7 52.2 1.0 1 0 0 1 1 1 1 Amino acid permease Fungal_trans_2 PF11951.8 KXH61599.1 - 4.3e-46 157.5 0.2 5.8e-46 157.0 0.2 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH61599.1 - 3.7e-07 30.2 5.8 7.1e-07 29.2 5.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short_C2 PF13561.6 KXH61600.1 - 7.1e-60 202.5 1.3 8.2e-60 202.3 1.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXH61600.1 - 8e-46 156.0 0.9 1.1e-45 155.6 0.9 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXH61600.1 - 6.8e-12 45.7 0.9 9.9e-12 45.1 0.9 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KXH61600.1 - 1.2e-05 25.3 0.2 2e-05 24.6 0.2 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ADH_zinc_N PF00107.26 KXH61600.1 - 0.0037 17.3 0.9 0.21 11.6 0.9 2.3 1 1 0 1 1 1 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.14 KXH61600.1 - 0.078 12.5 0.2 0.17 11.4 0.1 1.7 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Ldh_1_N PF00056.23 KXH61600.1 - 0.096 12.8 0.1 0.16 12.0 0.1 1.3 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Cutinase PF01083.22 KXH61601.1 - 4.9e-50 169.9 0.1 5.9e-50 169.7 0.1 1.1 1 0 0 1 1 1 1 Cutinase VirJ PF06057.11 KXH61601.1 - 0.0011 18.9 0.0 0.0015 18.4 0.0 1.1 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) Abhydrolase_2 PF02230.16 KXH61601.1 - 0.023 14.5 0.0 0.036 13.9 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase PE-PPE PF08237.11 KXH61601.1 - 0.067 12.7 0.1 0.094 12.3 0.1 1.2 1 0 0 1 1 1 0 PE-PPE domain zf-C2H2_3 PF13878.6 KXH61602.1 - 1.3e-09 37.7 0.1 2.2e-09 37.0 0.1 1.4 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO zf-C2H2_12 PF18658.1 KXH61602.1 - 0.18 11.4 0.2 8.9 6.0 0.0 2.3 2 0 0 2 2 2 0 Zinc-finger C2H2-type Vma12 PF11712.8 KXH61603.1 - 4.3e-45 153.2 0.0 6e-45 152.7 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF1772 PF08592.11 KXH61603.1 - 0.095 13.0 2.4 0.18 12.1 2.4 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1772) polyprenyl_synt PF00348.17 KXH61604.1 - 2e-74 249.9 0.0 3.4e-74 249.1 0.0 1.3 1 1 0 1 1 1 1 Polyprenyl synthetase HEPPP_synt_1 PF07307.11 KXH61604.1 - 0.018 14.7 0.0 0.028 14.0 0.0 1.2 1 0 0 1 1 1 0 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 Amidohydro_1 PF01979.20 KXH61605.1 - 6.9e-27 94.7 0.0 8.2e-26 91.1 0.0 2.2 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KXH61605.1 - 4.1e-15 56.2 0.1 1.1e-08 35.0 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Myb_DNA-binding PF00249.31 KXH61606.1 - 7.1e-22 77.3 9.4 4.9e-11 42.6 0.1 4.3 3 1 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KXH61606.1 - 2.7e-19 69.2 11.4 2.3e-09 37.4 0.1 4.6 3 1 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 KXH61606.1 - 0.039 14.3 5.4 0.1 13.0 0.6 3.0 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Sugar_tr PF00083.24 KXH61608.1 - 9.5e-124 413.7 29.6 1.1e-123 413.5 29.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH61608.1 - 2.3e-17 62.9 62.2 4e-15 55.6 39.4 2.6 1 1 2 3 3 3 2 Major Facilitator Superfamily Glyco_hydro_10 PF00331.20 KXH61609.1 - 1.5e-99 333.2 0.4 1.8e-99 332.9 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Glyco_hydro_42 PF02449.15 KXH61609.1 - 0.02 14.2 0.2 0.29 10.4 0.1 2.2 2 1 0 2 2 2 0 Beta-galactosidase AAA_16 PF13191.6 KXH61611.1 - 4.2e-10 40.3 0.2 1.6e-09 38.4 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain ATPase_2 PF01637.18 KXH61611.1 - 0.00011 22.2 0.1 0.00017 21.6 0.1 1.2 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea DUF815 PF05673.13 KXH61611.1 - 0.0029 16.8 0.0 0.0064 15.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_25 PF13481.6 KXH61611.1 - 0.0051 16.4 1.0 0.084 12.4 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_7 PF12775.7 KXH61611.1 - 0.0069 15.9 0.0 0.019 14.5 0.0 1.7 1 0 0 1 1 1 1 P-loop containing dynein motor region RsgA_GTPase PF03193.16 KXH61611.1 - 0.086 12.7 0.7 7.6 6.4 0.0 2.7 3 0 0 3 3 3 0 RsgA GTPase DNA_pol3_delta PF06144.13 KXH61611.1 - 0.15 11.8 0.1 0.24 11.2 0.1 1.2 1 0 0 1 1 1 0 DNA polymerase III, delta subunit AAA_29 PF13555.6 KXH61611.1 - 0.17 11.7 0.6 0.33 10.7 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain Fungal_trans_2 PF11951.8 KXH61612.1 - 9.3e-28 97.1 3.5 1.7e-15 56.7 0.8 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH61612.1 - 1e-08 35.1 12.2 1.9e-08 34.3 12.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AT_hook PF02178.19 KXH61612.1 - 0.13 12.2 7.0 0.21 11.6 5.4 2.2 2 0 0 2 2 2 0 AT hook motif Peptidase_M20 PF01546.28 KXH61613.1 - 1.9e-32 112.7 0.0 3.7e-32 111.7 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KXH61613.1 - 1.2e-13 50.9 0.0 4.1e-13 49.2 0.0 2.0 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KXH61613.1 - 0.0014 18.4 0.0 0.0027 17.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 ABC_tran PF00005.27 KXH61614.1 - 8.2e-51 172.1 0.1 3.9e-24 85.7 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC2_membrane PF01061.24 KXH61614.1 - 1.2e-50 171.9 32.5 6.2e-28 97.7 10.8 3.1 3 0 0 3 3 3 2 ABC-2 type transporter AAA_21 PF13304.6 KXH61614.1 - 1.8e-15 57.5 8.9 0.0019 18.1 0.0 4.3 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KXH61614.1 - 3.4e-10 39.8 0.4 4.1e-05 23.1 0.0 3.5 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KXH61614.1 - 4e-09 36.6 1.2 0.00096 19.1 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 KXH61614.1 - 3.8e-08 34.1 1.8 0.00084 19.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KXH61614.1 - 3.8e-08 32.9 1.7 0.0089 15.7 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KXH61614.1 - 8.2e-08 32.8 0.2 0.013 15.9 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 KXH61614.1 - 9.7e-08 32.4 0.1 0.079 13.2 0.0 3.6 3 0 0 3 3 3 2 AAA domain AAA_28 PF13521.6 KXH61614.1 - 4.5e-06 27.0 0.2 0.0096 16.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain PDR_CDR PF06422.12 KXH61614.1 - 7.8e-06 25.7 0.1 2.2e-05 24.3 0.1 1.7 1 0 0 1 1 1 1 CDR ABC transporter NACHT PF05729.12 KXH61614.1 - 1.5e-05 25.0 0.1 0.26 11.2 0.1 2.5 2 0 0 2 2 2 2 NACHT domain AAA_30 PF13604.6 KXH61614.1 - 4e-05 23.4 1.7 0.08 12.7 0.0 3.2 3 0 0 3 3 3 2 AAA domain T2SSE PF00437.20 KXH61614.1 - 6.3e-05 22.2 0.3 0.32 10.0 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_15 PF13175.6 KXH61614.1 - 0.00012 21.9 1.2 2.7 7.6 0.1 3.3 3 0 0 3 3 3 2 AAA ATPase domain MMR_HSR1 PF01926.23 KXH61614.1 - 0.00018 21.6 1.4 0.12 12.5 0.1 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_18 PF13238.6 KXH61614.1 - 0.00019 22.0 0.0 0.55 10.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 KXH61614.1 - 0.00047 20.5 0.6 0.076 13.3 0.2 2.8 2 1 0 2 2 2 1 AAA domain cobW PF02492.19 KXH61614.1 - 0.00065 19.3 2.0 0.53 9.8 0.3 2.4 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.6 KXH61614.1 - 0.00066 19.5 0.3 1 9.0 0.1 2.6 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 KXH61614.1 - 0.00072 19.2 0.3 1.1 8.8 0.0 2.7 3 0 0 3 3 2 2 AAA domain ATP_bind_1 PF03029.17 KXH61614.1 - 0.0012 18.7 0.1 0.81 9.4 0.0 2.4 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein FtsK_SpoIIIE PF01580.18 KXH61614.1 - 0.002 17.6 0.6 0.42 9.9 0.1 2.6 2 0 0 2 2 2 1 FtsK/SpoIIIE family PDR_assoc PF08370.11 KXH61614.1 - 0.0022 17.7 0.3 0.011 15.4 0.3 2.2 1 0 0 1 1 1 1 Plant PDR ABC transporter associated AAA_7 PF12775.7 KXH61614.1 - 0.0035 16.9 0.2 1.4 8.4 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region Pox_A32 PF04665.12 KXH61614.1 - 0.0048 16.4 1.4 0.15 11.5 0.1 2.6 2 1 0 2 2 2 1 Poxvirus A32 protein RNA_helicase PF00910.22 KXH61614.1 - 0.0049 17.2 0.1 4.8 7.6 0.0 2.9 3 0 0 3 3 2 0 RNA helicase PduV-EutP PF10662.9 KXH61614.1 - 0.0051 16.6 0.2 1.3 8.7 0.1 2.4 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_33 PF13671.6 KXH61614.1 - 0.0075 16.4 0.0 4.2 7.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 KXH61614.1 - 0.0077 16.2 0.0 1.3 8.9 0.0 2.3 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea Roc PF08477.13 KXH61614.1 - 0.01 16.0 0.1 4 7.7 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase SbcCD_C PF13558.6 KXH61614.1 - 0.014 15.6 1.6 5.4 7.3 0.2 3.7 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit KAP_NTPase PF07693.14 KXH61614.1 - 0.017 14.4 0.0 0.15 11.3 0.0 2.1 2 0 0 2 2 2 0 KAP family P-loop domain MobB PF03205.14 KXH61614.1 - 0.029 14.3 0.2 1.8 8.4 0.1 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_ATPase PF09818.9 KXH61614.1 - 0.032 13.0 0.2 1.1 7.9 0.2 2.8 3 0 0 3 3 3 0 Predicted ATPase of the ABC class IstB_IS21 PF01695.17 KXH61614.1 - 0.033 13.9 0.2 9.3 5.9 0.0 3.3 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_5 PF07728.14 KXH61614.1 - 0.034 14.1 0.2 12 5.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) SRPRB PF09439.10 KXH61614.1 - 0.043 13.2 0.6 7.8 5.9 0.0 2.4 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Septin PF00735.18 KXH61614.1 - 0.043 13.1 0.2 1.2 8.3 0.0 2.2 2 0 0 2 2 2 0 Septin AAA_11 PF13086.6 KXH61614.1 - 0.063 13.1 0.2 4.8 6.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain PRK PF00485.18 KXH61614.1 - 0.085 12.6 0.3 2.9 7.6 0.1 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Zeta_toxin PF06414.12 KXH61614.1 - 0.092 12.0 0.3 5.4 6.3 0.1 2.4 2 0 0 2 2 2 0 Zeta toxin NTPase_1 PF03266.15 KXH61614.1 - 0.1 12.5 0.2 7.2 6.5 0.0 3.3 4 0 0 4 4 4 0 NTPase ATP-synt_ab PF00006.25 KXH61614.1 - 0.12 12.0 0.1 2.9 7.5 0.0 2.5 3 0 0 3 3 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Dynamin_N PF00350.23 KXH61614.1 - 0.17 12.0 1.3 7.9 6.5 0.1 2.6 2 0 0 2 2 2 0 Dynamin family PhoH PF02562.16 KXH61614.1 - 0.17 11.3 0.2 7.7 5.9 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein DUF2075 PF09848.9 KXH61614.1 - 0.2 10.9 0.0 13 4.9 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_17 PF13207.6 KXH61614.1 - 0.2 12.1 0.1 2.6 8.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 KXH61614.1 - 0.22 11.6 1.1 1.3 9.1 0.9 2.4 3 0 0 3 3 1 0 Helicase HerA, central domain dNK PF01712.19 KXH61614.1 - 0.34 10.7 1.7 29 4.4 0.1 3.1 3 0 0 3 3 3 0 Deoxynucleoside kinase Glyco_hydro_43 PF04616.14 KXH61615.1 - 1.3e-51 175.6 3.4 1.6e-51 175.4 3.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 E1-E2_ATPase PF00122.20 KXH61616.1 - 1.9e-36 125.3 16.1 5.8e-30 104.1 0.2 3.5 3 0 0 3 3 3 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 KXH61616.1 - 2.7e-24 85.9 6.8 2.7e-24 85.9 6.8 2.5 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KXH61616.1 - 2.8e-19 70.2 0.0 1.2e-17 64.9 0.0 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KXH61616.1 - 9.2e-19 67.3 0.0 2e-18 66.3 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KXH61616.1 - 4.8e-13 48.6 0.1 4.8e-13 48.6 0.1 2.0 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KXH61616.1 - 0.00037 20.3 0.1 0.0024 17.6 0.2 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Exo_endo_phos PF03372.23 KXH61617.1 - 3.7e-10 39.7 0.0 1.3e-09 37.9 0.0 2.0 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family ADH_zinc_N PF00107.26 KXH61619.1 - 5.9e-26 91.0 0.2 1.1e-25 90.1 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXH61619.1 - 2.2e-18 67.6 0.0 7.4e-18 65.9 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXH61619.1 - 2.3e-09 37.1 0.0 2e-08 34.1 0.0 2.2 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 KXH61619.1 - 0.022 14.0 0.8 0.022 14.0 0.8 1.8 1 1 1 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Glyco_hydro_12 PF01670.16 KXH61620.1 - 1.4e-18 67.7 7.2 1.8e-18 67.3 7.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 PhzC-PhzF PF02567.16 KXH61621.1 - 5.6e-41 140.9 0.1 1.5e-40 139.4 0.1 1.6 1 1 0 1 1 1 1 Phenazine biosynthesis-like protein PALP PF00291.25 KXH61622.1 - 4e-59 200.5 2.3 6.5e-59 199.7 2.3 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Peptidase_M20 PF01546.28 KXH61622.1 - 7.2e-24 84.6 0.1 2.6e-23 82.8 0.0 1.9 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KXH61622.1 - 1.5e-17 63.5 0.0 3.2e-17 62.4 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KXH61622.1 - 0.0014 18.3 0.1 0.0048 16.6 0.0 1.9 2 0 0 2 2 2 1 Peptidase family M28 XPC-binding PF09280.11 KXH61622.1 - 0.15 11.9 0.0 3.4 7.5 0.0 2.5 2 0 0 2 2 2 0 XPC-binding domain RrnaAD PF00398.20 KXH61624.1 - 1.5e-06 27.5 0.0 4.1e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Glyco_transf_90 PF05686.12 KXH61625.1 - 2.8e-12 46.3 7.0 7.8e-11 41.5 0.0 2.6 3 0 0 3 3 3 2 Glycosyl transferase family 90 Arginase PF00491.21 KXH61626.1 - 3e-74 250.0 0.0 3.7e-74 249.7 0.0 1.0 1 0 0 1 1 1 1 Arginase family MARVEL PF01284.23 KXH61627.1 - 2.8e-07 30.6 17.3 5.4e-07 29.7 17.3 1.5 1 1 0 1 1 1 1 Membrane-associating domain DUF2070 PF09843.9 KXH61627.1 - 0.34 9.2 12.4 0.4 8.9 12.4 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Cnn_1N PF07989.11 KXH61629.1 - 8.2e-22 77.2 9.0 8.2e-22 77.2 9.0 11.9 8 2 4 13 13 13 4 Centrosomin N-terminal motif 1 Mto2_bdg PF12808.7 KXH61629.1 - 3.1e-12 46.6 8.8 3.1e-12 46.6 8.8 13.3 14 2 2 16 16 16 2 Micro-tubular organiser Mto1 C-term Mto2-binding region DegS PF05384.11 KXH61629.1 - 0.0012 18.3 3.4 0.0012 18.3 3.4 7.9 5 1 2 8 8 8 2 Sensor protein DegS DUF1479 PF07350.12 KXH61630.1 - 5.1e-164 546.0 0.0 5.8e-164 545.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) PhyH PF05721.13 KXH61630.1 - 0.1 12.9 0.1 8.5 6.6 0.0 2.3 2 0 0 2 2 2 0 Phytanoyl-CoA dioxygenase (PhyH) Methyltransf_11 PF08241.12 KXH61631.1 - 6.5e-07 29.9 0.0 1.4e-06 28.9 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH61631.1 - 2.9e-06 27.9 0.0 7.5e-06 26.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH61631.1 - 3.2e-05 23.8 0.0 3.9e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH61631.1 - 0.0021 18.8 0.0 0.003 18.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DUF1993 PF09351.10 KXH61632.1 - 1.3e-53 181.4 0.0 1.5e-53 181.3 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) DUF2235 PF09994.9 KXH61633.1 - 2.5e-77 260.1 0.4 3.7e-77 259.5 0.4 1.3 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) An_peroxidase PF03098.15 KXH61634.1 - 2.5e-39 135.3 0.0 7.8e-22 77.5 0.0 3.9 1 1 2 3 3 3 3 Animal haem peroxidase p450 PF00067.22 KXH61634.1 - 2e-06 26.9 0.1 9.2e-06 24.7 0.0 1.9 2 0 0 2 2 2 1 Cytochrome P450 PI_PP_C PF18365.1 KXH61634.1 - 0.19 11.7 0.3 0.58 10.1 0.3 1.8 1 0 0 1 1 1 0 Phosphoinositide phosphatase C-terminal domain CDH-cyt PF16010.5 KXH61635.1 - 1.5e-56 190.9 4.4 1.5e-56 190.9 4.4 2.2 3 0 0 3 3 3 1 Cytochrome domain of cellobiose dehydrogenase GMC_oxred_N PF00732.19 KXH61635.1 - 9.9e-33 113.8 0.0 1.9e-32 112.8 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXH61635.1 - 2.6e-20 73.4 0.3 9.7e-20 71.6 0.4 1.9 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KXH61635.1 - 2.5e-06 26.8 1.7 9.7e-06 24.9 0.8 2.3 3 0 0 3 3 3 1 FAD binding domain DAO PF01266.24 KXH61635.1 - 8.5e-06 25.6 2.3 4.1e-05 23.3 2.3 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KXH61635.1 - 4.7e-05 22.3 0.7 0.0003 19.6 0.6 2.0 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.6 KXH61635.1 - 0.00072 19.7 2.4 0.00074 19.7 0.3 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KXH61635.1 - 0.002 17.3 0.1 0.0038 16.3 0.1 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_oxidored PF12831.7 KXH61635.1 - 0.0039 16.6 1.1 0.0084 15.5 0.4 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXH61635.1 - 0.012 14.9 0.2 0.041 13.1 0.1 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KXH61635.1 - 0.02 14.2 0.3 0.036 13.3 0.3 1.4 1 0 0 1 1 1 0 FAD binding domain AF-4 PF05110.13 KXH61635.1 - 0.46 8.5 7.6 0.66 8.0 7.6 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Abhydrolase_3 PF07859.13 KXH61636.1 - 9.8e-44 149.7 1.0 1.2e-43 149.4 1.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KXH61636.1 - 5.4e-07 28.9 0.2 2.7e-06 26.6 0.2 1.7 1 1 0 1 1 1 1 Carboxylesterase family Tri3 PF07428.11 KXH61637.1 - 2.1e-119 399.1 0.0 2.6e-119 398.8 0.0 1.0 1 0 0 1 1 1 1 15-O-acetyltransferase Tri3 AATase PF07247.12 KXH61637.1 - 1.5e-05 23.8 0.0 9.6e-05 21.1 0.0 1.8 1 1 0 1 1 1 1 Alcohol acetyltransferase AMP-binding PF00501.28 KXH61638.1 - 2.4e-145 484.3 0.0 1.2e-76 258.1 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.20 KXH61638.1 - 3e-48 164.7 0.0 1.2e-35 123.1 0.0 3.4 2 1 0 2 2 2 2 Condensation domain PP-binding PF00550.25 KXH61638.1 - 1.8e-19 69.9 0.4 9.6e-10 38.7 0.0 3.2 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KXH61638.1 - 0.00015 22.7 0.1 1.5 9.8 0.0 3.3 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain p450 PF00067.22 KXH61639.1 - 5.5e-38 130.9 0.1 8.4e-38 130.3 0.1 1.2 1 0 0 1 1 1 1 Cytochrome P450 PAS_11 PF14598.6 KXH61639.1 - 0.081 13.1 0.0 17 5.6 0.0 2.4 2 0 0 2 2 2 0 PAS domain TRI5 PF06330.11 KXH61640.1 - 5.3e-158 525.6 1.7 6.2e-158 525.4 1.7 1.0 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) p450 PF00067.22 KXH61641.1 - 2.7e-36 125.3 0.0 3e-35 121.9 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 DUF3504 PF12012.8 KXH61641.1 - 0.19 11.6 0.0 0.44 10.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3504) ABC_membrane PF00664.23 KXH61642.1 - 5.1e-89 298.6 24.9 3.7e-47 161.3 6.8 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KXH61642.1 - 4.6e-66 221.5 0.0 1.4e-33 116.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KXH61642.1 - 8.2e-13 48.3 0.0 3e-05 23.6 0.1 3.7 3 2 1 4 4 3 3 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 KXH61642.1 - 1.6e-06 27.2 1.4 0.015 14.2 0.1 2.8 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_29 PF13555.6 KXH61642.1 - 9e-06 25.3 0.5 0.0032 17.2 0.0 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.6 KXH61642.1 - 5e-05 23.8 0.4 0.55 10.6 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 KXH61642.1 - 0.00014 22.2 0.2 0.046 14.0 0.0 3.5 2 2 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KXH61642.1 - 0.00062 19.7 0.1 0.38 10.7 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase Dala_Dala_lig_N PF01820.21 KXH61642.1 - 0.0018 18.7 0.0 4.5 7.8 0.0 2.9 3 0 0 3 3 2 2 D-ala D-ala ligase N-terminus Zeta_toxin PF06414.12 KXH61642.1 - 0.0092 15.3 0.0 0.065 12.5 0.0 2.1 2 0 0 2 2 2 1 Zeta toxin AAA_21 PF13304.6 KXH61642.1 - 0.016 15.0 0.1 2.9 7.6 0.0 3.2 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system PRK PF00485.18 KXH61642.1 - 0.017 14.9 0.1 7 6.3 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_5 PF07728.14 KXH61642.1 - 0.033 14.2 0.4 14 5.6 0.0 3.8 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) SbcCD_C PF13558.6 KXH61642.1 - 0.036 14.3 2.1 5.9 7.2 0.1 3.6 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit ATP-synt_ab PF00006.25 KXH61642.1 - 0.041 13.5 0.1 1.1 8.8 0.0 2.9 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_25 PF13481.6 KXH61642.1 - 0.049 13.2 0.0 0.41 10.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 KXH61642.1 - 0.11 12.4 0.2 1.8 8.4 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_23 PF13476.6 KXH61642.1 - 0.12 12.9 0.2 0.76 10.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 KXH61642.1 - 0.14 11.9 0.0 1.2 8.8 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain MMR_HSR1 PF01926.23 KXH61642.1 - 0.16 12.1 0.1 72 3.5 0.1 3.7 3 0 0 3 3 3 0 50S ribosome-binding GTPase MoaE PF02391.17 KXH61642.1 - 0.22 11.8 0.8 26 5.1 0.1 2.6 2 0 0 2 2 2 0 MoaE protein DUF87 PF01935.17 KXH61642.1 - 0.24 11.4 1.1 9.7 6.2 0.2 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain Glyco_hydro_43 PF04616.14 KXH61643.1 - 1.3e-49 169.1 7.6 1.3e-49 169.1 7.6 1.4 2 0 0 2 2 2 1 Glycosyl hydrolases family 43 CBM_6 PF03422.15 KXH61643.1 - 2.8e-37 127.8 2.3 2.8e-37 127.8 2.3 1.9 2 0 0 2 2 2 1 Carbohydrate binding module (family 6) DUF5010_C PF18099.1 KXH61643.1 - 1.8e-07 31.3 0.1 5.2e-07 29.8 0.1 1.7 1 0 0 1 1 1 1 DUF5010 C-terminal domain Glyco_hydro_32N PF00251.20 KXH61643.1 - 0.0016 18.1 5.9 0.0029 17.2 5.8 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain NFACT-C PF11923.8 KXH61682.1 - 1.4e-41 140.7 0.8 1.4e-41 140.7 0.8 3.3 2 1 1 3 3 3 1 NFACT protein C-terminal domain NFACT-R_1 PF05670.13 KXH61682.1 - 1.9e-33 115.4 0.0 5.4e-33 113.9 0.0 1.9 1 0 0 1 1 1 1 NFACT protein RNA binding domain FbpA PF05833.11 KXH61682.1 - 2.4e-29 102.4 17.2 2.4e-29 102.4 17.2 2.8 2 1 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) DUF5590 PF17881.1 KXH61682.1 - 0.12 12.5 0.0 0.32 11.1 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF5590) Rad17 PF03215.15 KXH61713.1 - 2.4e-23 83.1 0.0 8.2e-23 81.3 0.0 1.9 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 KXH61713.1 - 0.00035 21.0 0.0 0.00077 19.9 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KXH61713.1 - 0.00059 20.3 0.0 0.0016 18.9 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 KXH61713.1 - 0.0046 16.7 0.0 0.0098 15.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 KXH61713.1 - 0.0047 16.9 0.0 0.0094 16.0 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 KXH61713.1 - 0.03 14.6 0.0 0.059 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KXH61713.1 - 0.037 14.2 0.0 0.087 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 KXH61713.1 - 0.042 12.9 0.0 0.067 12.2 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein NACHT PF05729.12 KXH61713.1 - 0.048 13.6 0.1 0.11 12.4 0.1 1.6 1 0 0 1 1 1 0 NACHT domain AAA_28 PF13521.6 KXH61713.1 - 0.092 13.0 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KXH61713.1 - 0.11 13.0 0.0 0.33 11.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain Questin_oxidase PF14027.6 KXH61714.1 - 3.6e-95 319.4 2.8 4.3e-95 319.1 2.8 1.1 1 0 0 1 1 1 1 Questin oxidase-like p450 PF00067.22 KXH61735.1 - 7.1e-49 166.8 0.0 4.3e-48 164.2 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 Ank_2 PF12796.7 KXH61737.1 - 2.1e-11 44.2 0.0 5.9e-06 26.8 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXH61737.1 - 1.4e-09 37.4 0.0 8.1 7.4 0.0 6.4 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 KXH61737.1 - 1.2e-06 28.7 0.0 0.0056 17.0 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KXH61737.1 - 9.9e-06 25.8 0.4 5.6 7.6 0.0 5.2 5 0 0 5 5 5 2 Ankyrin repeat Ank_4 PF13637.6 KXH61737.1 - 0.0002 21.9 0.5 7.8 7.2 0.0 5.0 3 2 3 6 6 6 2 Ankyrin repeats (many copies) F-box PF00646.33 KXH61737.1 - 0.04 13.8 0.1 0.25 11.3 0.0 2.3 2 0 0 2 2 2 0 F-box domain SIKE PF05769.11 KXH61738.1 - 0.00045 20.2 0.0 0.00053 20.0 0.0 1.1 1 0 0 1 1 1 1 SIKE family IFT57 PF10498.9 KXH61738.1 - 0.0081 15.2 0.2 0.01 14.8 0.2 1.1 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 Apolipoprotein PF01442.18 KXH61738.1 - 0.0095 15.8 0.4 0.013 15.4 0.4 1.1 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Ald_deCOase PF11266.8 KXH61738.1 - 0.034 13.9 0.0 0.044 13.5 0.0 1.1 1 0 0 1 1 1 0 Long-chain fatty aldehyde decarbonylase Baculo_PEP_C PF04513.12 KXH61738.1 - 0.039 14.0 0.2 0.057 13.5 0.2 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Not3 PF04065.15 KXH61738.1 - 0.11 11.9 0.0 0.14 11.5 0.0 1.1 1 0 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component DUF2205 PF10224.9 KXH61738.1 - 0.12 12.4 1.2 9.5 6.3 0.3 2.2 1 1 1 2 2 2 0 Short coiled-coil protein DUF16 PF01519.16 KXH61738.1 - 0.13 12.7 0.4 11 6.5 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function DUF16 Rcd1 PF04078.13 KXH61748.1 - 1.3e-125 417.9 4.2 1.8e-125 417.4 4.2 1.2 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like TFIIA PF03153.13 KXH61748.1 - 0.0021 18.1 24.8 0.0029 17.7 24.8 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit RskA PF10099.9 KXH61748.1 - 0.0056 17.0 5.4 0.01 16.1 5.4 1.4 1 0 0 1 1 1 1 Anti-sigma-K factor rskA Androgen_recep PF02166.16 KXH61748.1 - 0.12 11.2 23.5 0.16 10.8 23.5 1.2 1 0 0 1 1 1 0 Androgen receptor EPL1 PF10513.9 KXH61748.1 - 0.16 12.3 6.0 0.28 11.6 6.0 1.4 1 0 0 1 1 1 0 Enhancer of polycomb-like eIF-3_zeta PF05091.12 KXH61748.1 - 0.18 10.7 9.3 0.24 10.3 9.3 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) SLC12 PF03522.15 KXH61748.1 - 0.39 9.7 6.5 0.53 9.3 6.5 1.2 1 0 0 1 1 1 0 Solute carrier family 12 PAT1 PF09770.9 KXH61748.1 - 0.4 8.9 17.9 0.5 8.6 17.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SprA-related PF12118.8 KXH61748.1 - 0.51 9.4 21.0 0.74 8.9 21.0 1.2 1 0 0 1 1 1 0 SprA-related family Pex14_N PF04695.13 KXH61748.1 - 0.92 10.1 18.1 1.6 9.4 18.1 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Velvet PF11754.8 KXH61748.1 - 0.94 9.4 9.9 1.4 8.8 9.9 1.3 1 0 0 1 1 1 0 Velvet factor Connexin PF00029.19 KXH61748.1 - 1 9.1 5.0 1.7 8.3 5.0 1.4 1 0 0 1 1 1 0 Connexin FAM60A PF15396.6 KXH61748.1 - 1.1 9.2 5.4 1.7 8.6 5.4 1.3 1 0 0 1 1 1 0 Protein Family FAM60A Otopetrin PF03189.13 KXH61748.1 - 1.3 7.8 6.7 0.076 11.8 1.5 1.5 2 0 0 2 2 2 0 Otopetrin HAUS6_N PF14661.6 KXH61748.1 - 1.3 8.5 12.8 13 5.3 10.4 2.2 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus Presenilin PF01080.17 KXH61748.1 - 1.5 7.5 12.7 2.2 7.0 12.7 1.2 1 0 0 1 1 1 0 Presenilin DivIC PF04977.15 KXH61748.1 - 2.2 8.1 14.2 5.9 6.7 14.2 1.8 1 0 0 1 1 1 0 Septum formation initiator Med15 PF09606.10 KXH61748.1 - 2.6 6.6 28.7 3.3 6.3 28.7 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal ALMT PF11744.8 KXH61748.1 - 3 6.6 7.3 4.6 6.0 7.3 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter RR_TM4-6 PF06459.12 KXH61748.1 - 3.3 7.5 9.3 5 6.9 9.3 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Suf PF05843.14 KXH61748.1 - 3.4 7.6 14.3 5.1 7.0 14.3 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Kei1 PF08552.11 KXH61748.1 - 3.5 7.5 8.5 6.6 6.6 8.5 1.4 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 PepSY_TM PF03929.16 KXH61748.1 - 3.6 7.2 6.1 5.2 6.7 6.1 1.2 1 0 0 1 1 1 0 PepSY-associated TM region CCDC53 PF10152.9 KXH61748.1 - 4.8 7.6 12.6 10 6.5 12.6 1.5 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex CPSF100_C PF13299.6 KXH61748.1 - 4.8 7.3 8.9 8 6.6 8.9 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Plasmodium_Vir PF05795.11 KXH61748.1 - 6 6.2 7.8 8.7 5.6 7.8 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Roughex PF06020.11 KXH61748.1 - 6.2 5.8 10.5 8.5 5.4 10.5 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Spore_coat_CotO PF14153.6 KXH61748.1 - 8 6.3 17.0 12 5.8 17.0 1.2 1 0 0 1 1 1 0 Spore coat protein CotO DND1_DSRM PF14709.7 KXH61752.1 - 0.0013 18.9 0.2 0.0022 18.2 0.2 1.5 1 1 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 dsrm PF00035.26 KXH61752.1 - 0.0076 16.9 0.0 0.016 15.9 0.0 1.6 1 0 0 1 1 1 1 Double-stranded RNA binding motif AA_kinase PF00696.28 KXH61759.1 - 1.4e-37 129.6 0.0 2.7e-37 128.6 0.0 1.5 1 0 0 1 1 1 1 Amino acid kinase family ACT PF01842.25 KXH61759.1 - 4e-10 39.3 0.7 0.00037 20.2 0.0 2.6 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.6 KXH61759.1 - 1.1e-07 31.6 3.1 0.0043 16.8 0.1 2.6 2 0 0 2 2 2 2 ACT domain RFX_DNA_binding PF02257.15 KXH61760.1 - 1.9e-27 95.7 0.1 4.5e-27 94.5 0.1 1.6 1 0 0 1 1 1 1 RFX DNA-binding domain TB2_DP1_HVA22 PF03134.19 KXH61761.1 - 2.5e-28 97.8 9.0 4.1e-28 97.1 9.0 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Mid1 PF12929.7 KXH61762.1 - 7.7e-155 516.3 4.8 9e-155 516.0 4.8 1.0 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.22 KXH61762.1 - 0.0008 20.0 8.2 0.009 16.6 4.0 2.5 2 0 0 2 2 2 2 Fz domain RAMP4 PF06624.12 KXH61764.1 - 9.7e-22 76.8 0.1 1.2e-21 76.6 0.1 1.1 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 SMAP PF15477.6 KXH61765.1 - 8.5e-11 42.7 4.6 8.5e-11 42.7 4.6 5.8 2 1 0 2 2 2 1 Small acidic protein family bZIP_1 PF00170.21 KXH61766.1 - 0.024 14.7 6.2 0.024 14.7 6.2 1.6 2 0 0 2 2 2 0 bZIP transcription factor IGR PF09597.10 KXH61767.1 - 9e-23 80.1 0.1 1.8e-22 79.2 0.1 1.5 1 0 0 1 1 1 1 IGR protein motif SNF2_N PF00176.23 KXH61768.1 - 2.3e-60 204.2 0.0 4e-60 203.4 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-C3HC4_3 PF13920.6 KXH61768.1 - 1e-09 38.1 10.7 2.2e-09 37.1 10.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXH61768.1 - 9.1e-08 31.9 13.7 2e-07 30.7 13.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXH61768.1 - 1.2e-07 31.9 13.1 2.4e-07 31.0 13.1 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KXH61768.1 - 8.9e-07 28.6 14.2 2e-06 27.5 14.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KXH61768.1 - 1.5e-06 27.9 10.0 3.2e-06 26.9 10.0 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 KXH61768.1 - 0.00011 22.4 12.0 0.00028 21.1 12.0 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain Helicase_C PF00271.31 KXH61768.1 - 0.00034 20.9 0.0 0.00068 20.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.6 KXH61768.1 - 0.00053 19.9 12.6 0.0012 18.8 12.6 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KXH61768.1 - 0.0063 16.5 11.4 0.018 15.1 11.4 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_4 PF14570.6 KXH61768.1 - 0.012 15.4 6.9 0.033 14.0 6.9 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain IBR PF01485.21 KXH61768.1 - 0.071 13.3 6.3 0.19 12.0 6.3 1.8 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain zf-C3HC4_4 PF15227.6 KXH61768.1 - 0.075 13.2 9.8 0.18 12.0 9.8 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 KXH61768.1 - 0.39 10.8 6.8 0.79 9.8 6.8 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_10 PF16685.5 KXH61768.1 - 0.96 9.6 7.3 2.2 8.5 7.3 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 DZR PF12773.7 KXH61768.1 - 1.3 9.1 5.2 3.4 7.8 5.2 1.7 1 0 0 1 1 1 0 Double zinc ribbon Sec10 PF07393.11 KXH61769.1 - 1.9e-165 552.3 0.0 2.3e-165 551.9 0.0 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 F-box-like PF12937.7 KXH61769.1 - 1.2e-07 31.5 0.3 5.4e-07 29.4 0.0 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KXH61769.1 - 0.0017 18.2 0.0 0.0037 17.1 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 KXH61769.1 - 0.042 13.7 0.0 0.12 12.3 0.0 1.7 1 0 0 1 1 1 0 F-box Pkinase PF00069.25 KXH61770.1 - 1.9e-64 217.6 0.0 2.3e-64 217.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXH61770.1 - 2.6e-35 122.0 0.0 3.6e-35 121.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXH61770.1 - 0.0011 18.3 0.0 0.0021 17.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Frag1 PF10277.9 KXH61771.1 - 1.4e-42 145.7 22.5 1.6e-42 145.5 22.5 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family Eisosome1 PF12757.7 KXH61772.1 - 4.9e-40 136.7 14.6 4.9e-40 136.7 14.6 3.9 3 2 1 4 4 4 1 Eisosome protein 1 DUF4718 PF15842.5 KXH61772.1 - 2.9 7.7 8.2 0.29 10.9 2.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4718) Y_phosphatase3 PF13350.6 KXH61773.1 - 3.6e-44 151.5 0.0 6.9e-44 150.5 0.0 1.4 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 KXH61773.1 - 1.4e-07 31.2 0.0 5.2e-07 29.4 0.0 1.7 2 0 0 2 2 2 1 Tyrosine phosphatase family Myotub-related PF06602.14 KXH61773.1 - 0.0016 17.4 0.0 0.0026 16.7 0.0 1.3 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain DSPc PF00782.20 KXH61773.1 - 0.0039 17.0 0.0 1.4 8.7 0.0 2.2 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KXH61773.1 - 0.0073 15.9 0.0 0.01 15.4 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Methyltransf_12 PF08242.12 KXH61774.1 - 5.1e-16 59.2 0.1 1.8e-15 57.5 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH61774.1 - 6.8e-15 55.6 0.0 1.7e-14 54.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH61774.1 - 1e-11 45.3 0.0 2.4e-11 44.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXH61774.1 - 3.9e-11 43.1 0.0 7.1e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH61774.1 - 7.5e-09 35.6 0.0 1.2e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 KXH61774.1 - 4.4e-06 27.7 0.0 1e-05 26.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXH61774.1 - 2.1e-05 24.0 0.0 3.3e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KXH61774.1 - 5e-05 22.9 0.0 8.7e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_8 PF05148.15 KXH61774.1 - 0.0036 17.2 0.0 0.052 13.4 0.0 2.3 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_32 PF13679.6 KXH61774.1 - 0.0058 16.6 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 KXH61774.1 - 0.0062 16.3 0.0 0.0099 15.6 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase DUF3419 PF11899.8 KXH61774.1 - 0.0088 15.3 0.0 0.017 14.4 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3419) PrmA PF06325.13 KXH61774.1 - 0.038 13.4 0.0 0.062 12.7 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) TPR_11 PF13414.6 KXH61775.1 - 3.8e-14 52.1 1.3 4.1e-05 23.2 0.0 3.9 3 1 1 4 4 4 3 TPR repeat TPR_14 PF13428.6 KXH61775.1 - 4.3e-10 39.6 9.8 0.00029 21.4 0.1 6.0 3 1 4 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 KXH61775.1 - 1.1e-08 35.4 5.2 1.6e-06 28.5 0.5 4.4 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 KXH61775.1 - 3.4e-07 29.9 0.4 0.031 14.5 0.2 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 KXH61775.1 - 4e-07 29.7 6.9 0.00013 21.8 0.5 5.2 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 KXH61775.1 - 5.1e-07 30.2 3.8 4.3e-05 24.1 0.5 3.6 4 1 0 4 4 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 KXH61775.1 - 2.5e-06 27.6 0.8 4.9e-05 23.4 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 KXH61775.1 - 3.6e-06 27.0 0.4 0.0012 19.1 0.1 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 KXH61775.1 - 1.7e-05 25.0 6.2 0.29 11.5 1.3 4.6 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 KXH61775.1 - 0.00031 21.2 0.5 1.3 9.8 0.1 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 KXH61775.1 - 0.00039 20.1 0.3 0.00039 20.1 0.3 3.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_20 PF14561.6 KXH61775.1 - 0.0007 19.9 2.4 0.0041 17.4 0.1 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat Methyltransf_1N PF02870.15 KXH61775.1 - 0.003 18.3 0.0 0.011 16.5 0.0 2.0 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain ChAPs PF09295.10 KXH61775.1 - 0.0075 15.3 0.0 0.0097 15.0 0.0 1.1 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_7 PF13176.6 KXH61775.1 - 0.018 15.1 3.5 0.11 12.6 0.3 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat NCA2 PF08637.10 KXH61775.1 - 0.024 13.8 0.0 0.055 12.6 0.0 1.5 2 0 0 2 2 2 0 ATP synthase regulation protein NCA2 ANAPC3 PF12895.7 KXH61775.1 - 0.029 14.6 0.2 0.098 12.9 0.1 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 BTAD PF03704.17 KXH61775.1 - 0.12 12.8 3.0 0.91 10.0 0.0 3.0 2 2 1 3 3 3 0 Bacterial transcriptional activator domain Polyketide_cyc PF03364.20 KXH61777.1 - 2.4e-26 92.5 0.0 5.5e-26 91.3 0.0 1.5 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 KXH61777.1 - 0.0011 19.3 0.8 0.0045 17.3 0.8 1.8 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport AA_permease PF00324.21 KXH61797.1 - 2.5e-93 313.3 41.6 3.1e-93 313.0 41.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KXH61797.1 - 5e-23 81.6 42.3 6.2e-23 81.3 42.3 1.1 1 0 0 1 1 1 1 Amino acid permease Bacteriocin_IId PF09221.10 KXH61797.1 - 4.2 7.6 10.9 0.15 12.2 1.4 3.0 3 0 0 3 3 3 0 Bacteriocin class IId cyclical uberolysin-like Ssu72 PF04722.13 KXH61799.1 - 4.2e-77 258.0 0.0 5.1e-77 257.8 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein Hema_HEFG PF02710.14 KXH61800.1 - 0.15 12.3 0.0 0.24 11.6 0.0 1.3 1 0 0 1 1 1 0 Hemagglutinin domain of haemagglutinin-esterase-fusion glycoprotein DUF3533 PF12051.8 KXH61827.1 - 3.8e-96 322.3 6.0 4.4e-96 322.1 6.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) ABC_tran PF00005.27 KXH61828.1 - 2.3e-46 157.7 0.4 4.1e-25 88.9 0.0 2.8 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 KXH61828.1 - 1.1e-29 103.7 45.0 1.6e-19 70.3 27.5 2.7 2 2 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.6 KXH61828.1 - 1.7e-21 77.3 2.4 0.00017 21.5 0.7 4.5 3 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KXH61828.1 - 2.2e-08 33.7 2.3 0.00035 20.3 0.3 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.19 KXH61828.1 - 1.5e-07 31.1 2.3 0.12 11.7 0.0 4.1 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KXH61828.1 - 1.7e-07 32.0 2.5 0.0081 16.7 0.3 2.5 2 0 0 2 2 2 2 AAA domain AAA_27 PF13514.6 KXH61828.1 - 0.00013 21.6 0.5 0.17 11.5 0.1 2.3 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KXH61828.1 - 0.00018 21.4 0.4 0.44 10.4 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_15 PF13175.6 KXH61828.1 - 0.00035 20.4 0.2 0.76 9.4 0.1 3.2 3 0 0 3 3 3 1 AAA ATPase domain AAA_16 PF13191.6 KXH61828.1 - 0.00078 19.9 0.1 1.9 8.8 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_30 PF13604.6 KXH61828.1 - 0.0015 18.3 2.0 1.7 8.3 0.1 3.1 3 1 0 3 3 3 2 AAA domain AAA_22 PF13401.6 KXH61828.1 - 0.02 15.1 0.6 8.8 6.6 0.0 3.3 2 1 0 2 2 2 0 AAA domain SRP54 PF00448.22 KXH61828.1 - 0.051 13.2 0.3 8.5 5.9 0.1 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Rad17 PF03215.15 KXH61828.1 - 0.09 12.7 0.0 9.5 6.1 0.0 2.6 3 0 0 3 3 3 0 Rad17 P-loop domain AAA_28 PF13521.6 KXH61828.1 - 0.1 12.9 0.1 7.9 6.7 0.1 2.4 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KXH61828.1 - 0.11 11.8 0.1 22 4.3 0.1 2.8 3 0 0 3 3 3 0 Zeta toxin Tail_VII PF17091.5 KXH61828.1 - 0.13 12.2 0.9 0.43 10.5 0.9 1.8 1 0 0 1 1 1 0 Inovirus G7P protein MukB PF04310.12 KXH61828.1 - 0.21 11.4 0.7 24 4.6 0.2 2.5 2 0 0 2 2 2 0 MukB N-terminal RraA-like PF03737.15 KXH61829.1 - 6.1e-37 127.1 0.1 7.6e-37 126.8 0.1 1.1 1 0 0 1 1 1 1 Aldolase/RraA Amidohydro_2 PF04909.14 KXH61830.1 - 5.5e-12 46.1 0.7 6.1e-12 45.9 0.7 1.1 1 0 0 1 1 1 1 Amidohydrolase Mycobact_memb PF05423.13 KXH61830.1 - 0.063 13.2 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Mycobacterium membrane protein Aconitase PF00330.20 KXH61832.1 - 1.7e-135 452.7 0.0 2.2e-135 452.2 0.0 1.2 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KXH61832.1 - 5e-37 127.2 0.0 9.5e-37 126.2 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF521 PF04412.13 KXH61832.1 - 0.012 14.4 0.0 0.023 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF521) MFS_1 PF07690.16 KXH61833.1 - 1.8e-29 102.8 16.5 2.9e-29 102.1 16.5 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Acetyltransf_1 PF00583.25 KXH61833.1 - 0.034 14.4 0.0 0.071 13.4 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family FAD_binding_3 PF01494.19 KXH61834.1 - 8.8e-14 51.5 3.0 3.8e-10 39.6 0.8 2.7 2 1 0 2 2 2 2 FAD binding domain SE PF08491.10 KXH61834.1 - 0.00055 19.1 0.0 0.0026 16.9 0.0 2.0 3 0 0 3 3 3 1 Squalene epoxidase Pyr_redox_2 PF07992.14 KXH61834.1 - 0.0043 16.3 0.2 0.066 12.4 0.1 2.0 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXH61834.1 - 0.047 13.9 0.4 0.15 12.3 0.1 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Methyltransf_11 PF08241.12 KXH61835.1 - 1.5e-07 31.9 0.1 3.2e-07 30.9 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH61835.1 - 1.6e-07 31.9 0.0 3.2e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH61835.1 - 7.6e-06 26.6 0.0 1e-05 26.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH61835.1 - 3.1e-05 23.8 0.0 4.6e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXH61835.1 - 0.0014 18.4 0.0 0.0017 18.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 KXH61835.1 - 0.041 13.5 0.0 0.063 12.9 0.0 1.3 1 1 0 1 1 1 0 Nodulation protein S (NodS) Oxidored_FMN PF00724.20 KXH61836.1 - 2.5e-89 299.9 0.0 2.9e-89 299.7 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family AP_endonuc_2 PF01261.24 KXH61836.1 - 0.012 15.1 0.0 3.2 7.1 0.0 2.4 1 1 1 2 2 2 0 Xylose isomerase-like TIM barrel DUF1848 PF08902.11 KXH61836.1 - 0.1 12.3 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1848) GFO_IDH_MocA PF01408.22 KXH61837.1 - 1.6e-19 70.9 0.1 2.8e-19 70.1 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.24 KXH61837.1 - 4e-05 24.1 0.0 8.1e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain GFO_IDH_MocA_C PF02894.17 KXH61837.1 - 0.0021 18.1 0.0 0.0046 17.0 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain PTN13_u3 PF16599.5 KXH61838.1 - 0.0025 17.9 1.4 0.0026 17.8 1.4 1.1 1 0 0 1 1 1 1 Unstructured linker region on PTN13 protein between PDZ DUF1349 PF07081.11 KXH61839.1 - 1.2e-21 77.2 0.0 1.7e-21 76.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) Aminotran_3 PF00202.21 KXH61840.1 - 2.4e-81 273.5 0.0 2.9e-81 273.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III MFS_1 PF07690.16 KXH61841.1 - 1.2e-25 90.2 49.2 1e-15 57.5 21.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3094 PF11293.8 KXH61841.1 - 8 6.3 6.2 14 5.5 0.7 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3094) HAD_2 PF13419.6 KXH61842.1 - 1.1e-16 61.4 0.0 1.4e-16 61.1 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KXH61842.1 - 4.3e-07 30.4 0.1 2.9e-06 27.7 0.1 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KXH61842.1 - 1.9e-05 24.7 0.1 7.5e-05 22.7 0.1 2.0 2 0 0 2 2 2 1 HAD-hyrolase-like NIF PF03031.18 KXH61842.1 - 0.0067 16.2 0.0 0.25 11.1 0.0 2.2 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase DUF4974 PF16344.5 KXH61842.1 - 0.011 15.8 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4974) GMC_oxred_N PF00732.19 KXH61843.1 - 8.4e-56 189.5 0.0 1.3e-55 188.9 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXH61843.1 - 2.6e-30 105.8 0.0 5.6e-30 104.8 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_3 PF13738.6 KXH61843.1 - 1e-06 28.2 0.1 0.029 13.6 0.0 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXH61843.1 - 0.00012 22.3 0.1 0.00034 20.8 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXH61843.1 - 0.00048 19.8 0.1 0.00081 19.1 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KXH61843.1 - 0.0016 17.6 0.1 0.0025 17.0 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 KXH61843.1 - 0.0031 16.7 0.4 0.031 13.4 0.3 2.1 2 0 0 2 2 2 1 FAD binding domain TrkA_N PF02254.18 KXH61843.1 - 0.0033 17.7 0.0 0.0069 16.6 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain Pyr_redox_2 PF07992.14 KXH61843.1 - 0.0064 15.8 0.1 0.011 15.0 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KXH61843.1 - 0.02 14.2 1.0 0.034 13.4 0.1 1.8 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.17 KXH61843.1 - 0.027 13.7 0.0 0.053 12.7 0.0 1.4 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.14 KXH61843.1 - 0.095 11.4 0.0 0.16 10.7 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Sugar_tr PF00083.24 KXH61845.1 - 2.4e-57 194.8 24.4 2.9e-57 194.5 24.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH61845.1 - 3.8e-14 52.4 34.5 3.8e-14 52.4 34.5 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KXH61845.1 - 3.9e-05 22.3 3.5 3.9e-05 22.3 3.5 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) zf-RNPHF PF08080.12 KXH61845.1 - 0.14 12.2 0.0 0.34 10.9 0.0 1.7 1 0 0 1 1 1 0 RNPHF zinc finger Glyco_hydro_43 PF04616.14 KXH61846.1 - 1.4e-60 205.1 0.0 1.8e-60 204.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 KXH61846.1 - 1.3e-14 54.4 0.0 1.9e-14 53.9 0.0 1.2 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain Abhydrolase_2 PF02230.16 KXH61847.1 - 1.2e-26 93.9 0.0 5.6e-26 91.7 0.0 1.9 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 KXH61847.1 - 0.00062 19.3 0.0 0.003 17.1 0.0 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 KXH61847.1 - 0.001 19.0 0.1 0.27 11.1 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXH61847.1 - 0.0018 18.9 0.0 0.11 13.1 0.0 2.1 1 1 1 2 2 2 1 Alpha/beta hydrolase family FSH1 PF03959.13 KXH61847.1 - 0.0043 16.7 0.0 0.0073 16.0 0.0 1.5 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Hydrolase_4 PF12146.8 KXH61847.1 - 0.071 12.4 0.0 31 3.7 0.0 2.9 3 0 0 3 3 3 0 Serine aminopeptidase, S33 MFS_1 PF07690.16 KXH61849.1 - 4.1e-17 62.1 82.9 8e-13 48.0 46.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KXH61849.1 - 2.7 6.2 11.3 0.22 9.8 3.9 2.3 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Peptidase_S10 PF00450.22 KXH61850.1 - 2.8e-80 270.8 0.0 3.4e-80 270.5 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase DUF3079 PF11278.8 KXH61851.1 - 0.11 12.4 1.0 0.11 12.4 1.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3079) Fructosamin_kin PF03881.14 KXH61852.1 - 4.2e-15 55.7 0.0 6.6e-15 55.1 0.0 1.2 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 KXH61852.1 - 0.012 15.5 0.0 0.1 12.5 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family DUF5039 PF16442.5 KXH61852.1 - 0.066 12.7 0.1 0.11 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5039) HLH PF00010.26 KXH61855.1 - 0.00012 22.0 0.1 0.00026 20.9 0.1 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain HALZ PF02183.18 KXH61855.1 - 0.058 13.6 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper TAL_FSA PF00923.19 KXH61856.1 - 1.7e-20 73.6 0.0 2.6e-20 72.9 0.0 1.3 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase Sugar_tr PF00083.24 KXH61857.1 - 2e-86 290.7 24.8 2.5e-86 290.3 24.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH61857.1 - 1.9e-14 53.4 48.9 2.9e-08 33.1 22.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2838 PF10998.8 KXH61857.1 - 7.9 6.8 9.7 1.6 9.0 1.7 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2838) Bac_rhamnosid_C PF17390.2 KXH61858.1 - 3.7e-07 29.8 0.1 8e-07 28.8 0.1 1.6 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain Bac_rhamnosid6H PF17389.2 KXH61858.1 - 0.00033 20.0 0.0 0.093 12.0 0.0 2.3 2 0 0 2 2 2 2 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain DUF1080 PF06439.11 KXH61858.1 - 0.0021 18.2 0.0 0.0049 17.0 0.0 1.6 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1080) DUF608 PF04685.13 KXH61858.1 - 0.014 14.6 0.0 0.023 13.9 0.0 1.2 1 0 0 1 1 1 0 Glycosyl-hydrolase family 116, catalytic region Laminin_G_3 PF13385.6 KXH61858.1 - 0.11 12.6 0.1 0.23 11.6 0.1 1.4 1 0 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily Fungal_trans PF04082.18 KXH61859.1 - 4.5e-16 58.7 0.8 7.6e-16 57.9 0.8 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ank_2 PF12796.7 KXH61862.1 - 4.7e-21 75.2 0.2 1.7e-07 31.7 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXH61862.1 - 1.1e-16 59.2 0.1 0.0089 16.5 0.0 4.8 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 KXH61862.1 - 1.5e-15 57.1 0.1 0.00012 22.3 0.1 3.6 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXH61862.1 - 3.3e-13 49.9 0.1 2.7e-05 24.6 0.0 4.1 3 1 0 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 KXH61862.1 - 1.7e-09 37.7 3.0 0.00014 22.2 0.0 4.2 3 1 1 4 4 4 2 Ankyrin repeat F-box PF00646.33 KXH61862.1 - 0.025 14.5 0.1 0.054 13.4 0.1 1.5 1 0 0 1 1 1 0 F-box domain Thiamine_BP PF01910.17 KXH61873.1 - 4.6e-11 42.5 0.0 5.3e-11 42.3 0.0 1.1 1 0 0 1 1 1 1 Thiamine-binding protein Cpn60_TCP1 PF00118.24 KXH61888.1 - 3.2e-143 477.9 11.5 3.8e-143 477.7 11.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Mei5 PF10376.9 KXH61888.1 - 0.13 12.1 0.6 0.88 9.4 0.1 2.3 2 0 0 2 2 2 0 Double-strand recombination repair protein Acetyltransf_7 PF13508.7 KXH61889.1 - 3.4e-07 30.6 0.0 7.2e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXH61889.1 - 0.0014 18.9 0.1 0.057 13.6 0.0 2.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXH61889.1 - 0.0031 17.5 0.0 0.13 12.2 0.0 2.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KXH61889.1 - 0.11 12.6 0.2 0.54 10.3 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Sporozoite_P67 PF05642.11 KXH61890.1 - 0.35 8.9 7.7 0.43 8.6 7.7 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen FGE-sulfatase PF03781.16 KXH61891.1 - 3.6e-40 138.2 1.1 5.3e-40 137.6 1.1 1.2 1 0 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 AAA_16 PF13191.6 KXH61891.1 - 5.7e-06 26.8 2.3 0.00061 20.2 2.3 2.6 1 1 0 1 1 1 1 AAA ATPase domain DUF953 PF06110.11 KXH61891.1 - 1.3e-05 24.8 0.0 2.4e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Rad17 PF03215.15 KXH61891.1 - 3.3e-05 23.9 0.0 5.4e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 KXH61891.1 - 6.2e-05 23.3 0.7 0.00036 20.8 0.7 2.1 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 KXH61891.1 - 0.00036 20.5 1.1 0.00088 19.2 0.2 2.2 2 1 0 2 2 2 1 NACHT domain AAA_18 PF13238.6 KXH61891.1 - 0.0011 19.5 0.0 0.0022 18.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 KXH61891.1 - 0.0025 17.4 0.0 0.0054 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 KXH61891.1 - 0.0026 18.3 0.0 0.0041 17.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.6 KXH61891.1 - 0.004 17.3 0.0 0.0083 16.2 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_29 PF13555.6 KXH61891.1 - 0.0085 15.8 0.0 0.02 14.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain T2SSE PF00437.20 KXH61891.1 - 0.013 14.5 0.0 0.022 13.8 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_14 PF13173.6 KXH61891.1 - 0.018 15.1 0.0 0.22 11.6 0.0 2.5 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KXH61891.1 - 0.021 15.0 0.0 0.047 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KXH61891.1 - 0.024 14.4 0.0 0.039 13.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KXH61891.1 - 0.025 14.6 0.5 0.07 13.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) APS_kinase PF01583.20 KXH61891.1 - 0.026 14.4 0.0 0.05 13.5 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase PhoH PF02562.16 KXH61891.1 - 0.028 13.9 0.0 0.6 9.5 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein TsaE PF02367.17 KXH61891.1 - 0.036 14.1 0.0 0.072 13.1 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase_2 PF01637.18 KXH61891.1 - 0.044 13.7 0.0 0.26 11.2 0.0 1.9 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea ABC_tran PF00005.27 KXH61891.1 - 0.057 13.9 0.3 0.14 12.7 0.1 1.6 2 0 0 2 2 1 0 ABC transporter IstB_IS21 PF01695.17 KXH61891.1 - 0.06 13.1 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein NTPase_1 PF03266.15 KXH61891.1 - 0.066 13.1 0.1 0.11 12.4 0.1 1.3 1 0 0 1 1 1 0 NTPase AAA PF00004.29 KXH61891.1 - 0.073 13.5 0.1 0.16 12.4 0.1 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 KXH61891.1 - 0.074 12.6 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 KXH61891.1 - 0.075 13.4 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 RNA helicase Pox_A32 PF04665.12 KXH61891.1 - 0.075 12.5 0.2 0.51 9.8 0.0 2.0 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_30 PF13604.6 KXH61891.1 - 0.085 12.6 0.0 0.18 11.5 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KXH61891.1 - 0.17 12.2 0.0 2.1 8.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 KXH61891.1 - 0.18 11.1 0.0 0.3 10.4 0.0 1.2 1 0 0 1 1 1 0 KaiC SBP_bac_5 PF00496.22 KXH61892.1 - 8e-46 156.7 0.0 1.1e-45 156.3 0.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle MFS_1 PF07690.16 KXH61893.1 - 9.8e-16 57.6 2.9 1.3e-15 57.3 2.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 KXH61893.1 - 0.011 15.0 0.4 0.015 14.6 0.4 1.1 1 0 0 1 1 1 0 Uncharacterised MFS-type transporter YbfB Sel_put PF04328.13 KXH61893.1 - 0.099 12.7 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Selenoprotein, putative GCV_H PF01597.19 KXH61906.1 - 2.6e-35 121.0 1.4 3.2e-35 120.7 1.4 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein RnfC_N PF13375.6 KXH61906.1 - 0.045 13.7 0.1 0.067 13.1 0.1 1.3 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain Biotin_lipoyl PF00364.22 KXH61906.1 - 0.071 13.0 0.9 0.11 12.3 0.2 1.7 2 0 0 2 2 2 0 Biotin-requiring enzyme MCR_alpha PF02249.17 KXH61906.1 - 0.088 13.3 0.0 0.12 12.8 0.0 1.2 1 0 0 1 1 1 0 Methyl-coenzyme M reductase alpha subunit, C-terminal domain Porphobil_deam PF01379.20 KXH61907.1 - 1.4e-75 253.3 0.0 2.1e-75 252.7 0.0 1.3 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 KXH61907.1 - 1.9e-17 63.4 0.2 3.6e-17 62.5 0.2 1.5 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain ELO PF01151.18 KXH61909.1 - 4.2e-63 213.2 15.3 5e-63 212.9 15.3 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family COX5A PF02284.16 KXH61910.1 - 5.9e-41 138.7 0.1 7.3e-41 138.4 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va EMP24_GP25L PF01105.24 KXH61911.1 - 1.9e-46 158.3 1.3 2.3e-46 158.0 1.3 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD PhoD PF09423.10 KXH61912.1 - 1.3e-44 152.7 0.0 2.1e-44 152.0 0.0 1.3 1 0 0 1 1 1 1 PhoD-like phosphatase Cyclase PF04199.13 KXH61913.1 - 9.8e-13 48.5 0.0 1.8e-12 47.7 0.0 1.5 1 0 0 1 1 1 1 Putative cyclase Metallophos PF00149.28 KXH61914.1 - 1e-37 130.6 0.0 2.8e-37 129.2 0.0 1.7 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase adh_short_C2 PF13561.6 KXH61915.1 - 8.6e-60 202.2 3.4 2e-59 201.0 3.4 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXH61915.1 - 1.1e-34 119.7 4.5 7e-34 117.0 4.5 1.9 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXH61915.1 - 1.4e-06 28.3 1.0 5.2e-06 26.5 1.0 1.8 1 1 0 1 1 1 1 KR domain 2-Hacid_dh_C PF02826.19 KXH61915.1 - 0.028 13.8 0.0 0.058 12.7 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 KXH61915.1 - 0.029 14.3 0.1 0.06 13.2 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TauD PF02668.16 KXH61916.1 - 1.4e-38 133.3 0.2 2e-38 132.8 0.2 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Granulin PF00396.18 KXH61917.1 - 3.7 8.0 29.9 3.2 8.2 4.1 3.5 2 1 1 3 3 3 0 Granulin Promethin PF16015.5 KXH61918.1 - 0.48 10.4 2.9 0.95 9.4 2.9 1.4 1 0 0 1 1 1 0 Promethin Methyltransf_23 PF13489.6 KXH61919.1 - 7.2e-08 32.4 0.0 1.1e-07 31.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH61919.1 - 1.3e-07 32.2 0.0 2.5e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH61919.1 - 2.7e-05 24.7 0.0 6.2e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH61919.1 - 0.00029 21.5 0.0 0.00059 20.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH61919.1 - 0.00038 20.3 0.0 0.00088 19.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXH61919.1 - 0.0089 15.4 0.0 0.014 14.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family F-box-like PF12937.7 KXH61924.1 - 2.7e-09 36.8 4.0 1.8e-08 34.1 4.0 2.4 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 KXH61924.1 - 0.0034 17.2 6.3 0.0041 17.0 2.2 2.7 2 1 0 2 2 2 1 F-box domain Glycogen_syn PF05693.13 KXH61925.1 - 0 1173.3 0.0 0 1173.0 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glyco_transf_4 PF13439.6 KXH61925.1 - 1.1e-05 25.5 0.4 2.3e-05 24.5 0.4 1.7 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 KXH61925.1 - 5.3e-05 23.7 0.1 0.00012 22.5 0.1 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_5 PF08323.11 KXH61925.1 - 6.2e-05 22.8 0.1 0.00012 21.9 0.1 1.5 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 KXH61925.1 - 0.00018 21.1 0.0 0.028 13.9 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KXH61925.1 - 0.00067 20.1 0.0 0.48 10.9 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 Pkinase PF00069.25 KXH61926.1 - 4.1e-67 226.3 0.0 5.5e-67 225.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXH61926.1 - 4.3e-36 124.5 0.0 8.7e-36 123.5 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXH61926.1 - 0.00031 20.2 0.0 0.00051 19.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KXH61926.1 - 0.0022 17.4 0.1 0.0053 16.1 0.1 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KXH61926.1 - 0.051 13.2 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Haspin_kinase PF12330.8 KXH61926.1 - 0.072 12.0 0.1 0.11 11.5 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 KXH61926.1 - 0.14 10.9 0.0 0.14 10.9 0.0 2.2 3 0 0 3 3 3 0 Fungal protein kinase Pmp3 PF01679.17 KXH61928.1 - 8.5e-20 70.7 7.3 1.1e-19 70.4 7.3 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator zf-RanBP PF00641.18 KXH61929.1 - 2.5e-18 65.1 13.3 8.6e-11 41.0 1.6 2.3 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others RRM_1 PF00076.22 KXH61929.1 - 5.2e-08 32.6 0.0 1e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNase_T PF00929.24 KXH61929.1 - 1.8e-06 28.6 0.0 2.7e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Exonuclease CAF1C_H4-bd PF12265.8 KXH61930.1 - 1.4e-26 92.5 0.2 1.5e-25 89.2 0.2 2.7 3 0 0 3 3 3 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 KXH61930.1 - 3.4e-26 91.0 4.9 3.5e-06 27.7 0.1 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXH61930.1 - 6e-06 26.5 0.8 0.15 12.3 0.1 4.2 2 1 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Leader_Erm PF08253.11 KXH61930.1 - 0.4 11.0 1.0 3.2 8.3 0.4 2.4 2 0 0 2 2 2 0 Erm Leader peptide XRN_M PF17846.1 KXH61931.1 - 1.5e-97 327.3 3.0 2.6e-97 326.6 3.0 1.3 1 0 0 1 1 1 1 Xrn1 helical domain XRN_N PF03159.18 KXH61931.1 - 5.2e-94 314.2 0.0 7.8e-94 313.6 0.0 1.3 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN1_D1 PF18332.1 KXH61931.1 - 1.4e-69 233.7 0.0 2.7e-69 232.8 0.0 1.5 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D1 domain XRN1_D2_D3 PF18334.1 KXH61931.1 - 8.9e-35 118.8 0.0 2.5e-34 117.3 0.0 1.8 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D2/D3 domain SH3_12 PF18129.1 KXH61931.1 - 2.1e-22 79.0 0.1 4.3e-22 78.0 0.1 1.6 1 0 0 1 1 1 1 Xrn1 SH3-like domain Xrn1_D3 PF18194.1 KXH61931.1 - 1.8e-06 27.9 0.0 3.9e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 Exoribonuclease 1 Domain-3 SPC22 PF04573.12 KXH61932.1 - 6.1e-40 136.5 2.1 7.8e-39 132.9 2.1 1.9 1 1 0 1 1 1 1 Signal peptidase subunit Phage_ABA_S PF18066.1 KXH61932.1 - 0.062 14.0 0.0 0.14 12.8 0.0 1.6 1 0 0 1 1 1 0 Phage ABA sandwich domain Peptidase_C48 PF02902.19 KXH61933.1 - 1.2e-30 107.0 0.0 2.2e-30 106.1 0.0 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain WD40 PF00400.32 KXH61934.1 - 1.6e-24 85.7 2.0 4.7e-06 27.2 0.0 5.7 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXH61934.1 - 0.00041 20.6 0.0 0.13 12.6 0.0 3.0 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KXH61934.1 - 0.021 14.1 0.0 0.17 11.1 0.0 2.3 3 1 0 4 4 4 0 WD40-like domain Nha1_C PF08619.10 KXH61934.1 - 0.044 13.0 11.6 0.078 12.2 11.6 1.3 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus PRR20 PF15708.5 KXH61934.1 - 0.057 13.3 1.8 0.11 12.4 1.8 1.4 1 0 0 1 1 1 0 Proline-rich protein family 20 Proteasome PF00227.26 KXH61935.1 - 2.4e-23 82.6 0.0 7.2e-20 71.3 0.0 2.0 2 0 0 2 2 2 2 Proteasome subunit PNTB PF02233.16 KXH61940.1 - 1.1e-167 558.7 26.7 1.2e-167 558.5 26.7 1.0 1 0 0 1 1 1 1 NAD(P) transhydrogenase beta subunit TPP_enzyme_M PF00205.22 KXH61940.1 - 0.029 14.1 0.3 0.37 10.5 0.1 2.5 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Cytochrom_B561 PF03188.16 KXH61940.1 - 6.8 6.8 10.9 0.45 10.6 3.9 2.6 2 2 0 2 2 2 0 Eukaryotic cytochrome b561 zf-C2H2 PF00096.26 KXH61941.1 - 3.5e-05 24.0 17.8 0.67 10.5 0.9 4.8 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXH61941.1 - 5.6 8.1 26.9 0.68 10.9 0.8 5.5 5 1 0 5 5 5 0 C2H2-type zinc finger HSP70 PF00012.20 KXH62009.1 - 5.3e-11 41.4 0.3 1.5e-09 36.6 0.2 2.0 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 KXH62009.1 - 0.012 14.5 0.1 0.062 12.1 0.0 1.9 2 0 0 2 2 2 0 MreB/Mbl protein Thaumatin PF00314.17 KXH62010.1 - 3.3e-66 223.0 5.1 4.6e-66 222.5 5.1 1.2 1 0 0 1 1 1 1 Thaumatin family Glyco_hydro_64 PF16483.5 KXH62010.1 - 0.13 11.5 0.1 10 5.2 0.0 2.2 2 0 0 2 2 2 0 Beta-1,3-glucanase Ank_4 PF13637.6 KXH62011.1 - 2.2e-08 34.5 0.0 3.4e-06 27.5 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXH62011.1 - 7.7e-08 32.8 0.0 1e-06 29.2 0.0 2.2 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXH62011.1 - 3.8e-07 29.9 0.1 0.0068 16.8 0.0 4.0 4 1 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 KXH62011.1 - 2.8e-06 27.5 0.0 0.39 11.2 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 KXH62011.1 - 2.8e-05 24.3 0.0 0.67 10.3 0.0 3.2 2 1 0 2 2 2 2 Ankyrin repeats (many copies) TFIIS_C PF01096.18 KXH62012.1 - 2.5e-21 75.2 2.4 2.5e-21 75.2 2.4 2.7 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 KXH62012.1 - 4.5e-07 29.6 2.0 3.8e-06 26.7 0.2 2.4 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.7 KXH62012.1 - 0.00095 19.1 5.8 0.037 14.0 0.6 2.4 2 1 0 2 2 2 2 Transposase zinc-ribbon domain IBR PF01485.21 KXH62012.1 - 0.012 15.9 6.4 1 9.6 0.2 2.4 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain Desulfoferrod_N PF06397.12 KXH62012.1 - 0.019 14.6 0.6 0.18 11.5 0.1 2.3 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain zf-3CxxC_2 PF17180.4 KXH62012.1 - 0.15 12.8 4.3 5.3 7.8 0.1 2.3 2 1 0 2 2 2 0 Zinc-binding domain zinc_ribbon_4 PF13717.6 KXH62012.1 - 3.6 7.6 8.9 23 5.0 0.2 3.7 4 0 0 4 4 4 0 zinc-ribbon domain Med31 PF05669.12 KXH62013.1 - 1.2e-36 124.6 1.1 1.4e-36 124.3 1.1 1.0 1 0 0 1 1 1 1 SOH1 SIP1 PF04938.12 KXH62014.1 - 6.2e-07 29.3 0.0 0.00026 20.8 0.0 3.1 2 1 0 2 2 2 2 Survival motor neuron (SMN) interacting protein 1 (SIP1) RNR_inhib PF08591.10 KXH62015.1 - 1.4e-34 119.6 0.0 2.4e-34 118.9 0.0 1.3 1 0 0 1 1 1 1 Ribonucleotide reductase inhibitor Ribosomal_S27e PF01667.17 KXH62016.1 - 4.5e-28 96.7 7.5 6.1e-28 96.3 7.5 1.2 1 0 0 1 1 1 1 Ribosomal protein S27 TF_Zn_Ribbon PF08271.12 KXH62016.1 - 0.2 11.2 3.7 0.3 10.6 3.7 1.2 1 0 0 1 1 1 0 TFIIB zinc-binding zf-C2HC5 PF06221.13 KXH62016.1 - 1.1 9.3 7.1 3.8 7.6 4.4 2.3 2 1 0 2 2 2 0 Putative zinc finger motif, C2HC5-type Phosducin PF02114.16 KXH62017.1 - 2.4e-13 49.6 0.2 3.7e-13 49.0 0.2 1.2 1 0 0 1 1 1 1 Phosducin Thioredoxin PF00085.20 KXH62017.1 - 0.0034 17.3 0.0 0.006 16.5 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin NPH-II PF12011.8 KXH62017.1 - 0.039 13.8 0.0 0.057 13.3 0.0 1.3 1 0 0 1 1 1 0 RNA helicase NPH-II LRR_8 PF13855.6 KXH62018.1 - 8e-08 31.9 4.9 4.9e-06 26.2 2.5 3.1 2 1 1 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 KXH62018.1 - 7.3e-07 29.4 0.2 2.5e-05 24.5 0.1 3.3 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KXH62018.1 - 0.012 16.1 1.9 18 6.4 0.0 4.5 4 0 0 4 4 4 0 Leucine Rich Repeat RTC PF01137.21 KXH62019.1 - 1.6e-48 164.8 0.4 6.6e-37 126.8 0.0 2.2 2 0 0 2 2 2 2 RNA 3'-terminal phosphate cyclase AhpC-TSA PF00578.21 KXH62021.1 - 2e-37 127.9 0.0 2.6e-37 127.5 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KXH62021.1 - 7.5e-12 45.2 0.0 1.1e-11 44.7 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 KXH62021.1 - 2.2e-11 43.4 0.0 4.2e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin CDC45 PF02724.14 KXH62022.1 - 2.5 6.3 9.3 2.6 6.2 9.3 1.0 1 0 0 1 1 1 0 CDC45-like protein adh_short PF00106.25 KXH62026.1 - 3e-13 49.7 0.0 4.1e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXH62026.1 - 3e-09 36.8 0.0 3.8e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 KXH62026.1 - 3.2e-07 30.4 0.7 5.6e-07 29.6 0.7 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KXH62026.1 - 4e-06 26.6 1.0 6.4e-06 25.9 1.0 1.3 1 0 0 1 1 1 1 NmrA-like family KR PF08659.10 KXH62026.1 - 0.00039 20.4 0.0 0.00048 20.1 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXH62026.1 - 0.0061 16.0 0.0 0.0092 15.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.17 KXH62026.1 - 0.026 15.1 0.1 0.073 13.7 0.0 1.7 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent PALP PF00291.25 KXH62026.1 - 0.089 12.2 0.1 0.13 11.7 0.1 1.2 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme DapB_N PF01113.20 KXH62026.1 - 0.15 12.2 0.2 1.8 8.7 0.2 2.0 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus MFS_1 PF07690.16 KXH62027.1 - 2.7e-25 89.0 19.4 2.7e-25 89.0 19.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH62027.1 - 5e-08 32.2 2.5 5e-08 32.2 2.5 3.3 2 2 1 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.13 KXH62027.1 - 0.0003 19.4 0.5 0.00047 18.7 0.5 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2263 PF10021.9 KXH62028.1 - 7.7e-20 71.8 0.0 2.1e-19 70.4 0.0 1.7 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) Macro PF01661.21 KXH62028.1 - 0.0039 17.2 0.0 0.049 13.7 0.0 2.2 2 0 0 2 2 2 1 Macro domain DUF735 PF05246.11 KXH62028.1 - 0.0091 16.0 0.1 0.015 15.3 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF735) DivIC PF04977.15 KXH62028.1 - 0.17 11.7 0.8 0.34 10.7 0.8 1.4 1 0 0 1 1 1 0 Septum formation initiator DASH_Spc19 PF08287.11 KXH62028.1 - 0.17 11.7 1.1 0.33 10.8 0.7 1.5 1 1 0 1 1 1 0 Spc19 FlaC_arch PF05377.11 KXH62028.1 - 0.23 11.9 1.8 0.47 10.9 1.8 1.4 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) EcKinase PF02958.20 KXH62029.1 - 7.9e-14 51.7 0.0 1.2e-13 51.0 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase APH PF01636.23 KXH62029.1 - 9.4e-07 29.0 0.2 3.7e-06 27.1 0.0 2.0 2 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KXH62029.1 - 0.00068 19.3 0.0 0.0011 18.6 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.11 KXH62029.1 - 0.17 10.7 0.0 0.28 10.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Hydrophobin PF01185.18 KXH62031.1 - 1.2e-10 41.8 10.6 1.7e-10 41.3 10.6 1.2 1 0 0 1 1 1 1 Fungal hydrophobin Transferase PF02458.15 KXH62032.1 - 2.3e-08 33.1 0.0 1.3e-07 30.6 0.0 2.2 2 1 0 2 2 2 1 Transferase family DUF3433 PF11915.8 KXH62034.1 - 7.7e-29 100.0 29.2 1.3e-20 73.6 1.7 4.4 5 0 0 5 5 5 2 Protein of unknown function (DUF3433) Abhydrolase_3 PF07859.13 KXH62035.1 - 3.1e-11 43.6 0.8 1.4e-09 38.2 0.8 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KXH62035.1 - 1e-07 31.7 0.0 1.2e-06 28.2 0.0 2.0 1 1 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 KXH62035.1 - 6.4e-07 29.1 0.0 0.00014 21.5 0.0 2.9 3 0 0 3 3 3 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 KXH62035.1 - 1.3e-06 27.9 0.0 0.002 17.4 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KXH62035.1 - 1.6e-05 24.7 0.1 0.019 14.6 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Esterase_phd PF10503.9 KXH62035.1 - 0.015 14.8 0.3 0.17 11.4 0.3 2.0 1 1 0 1 1 1 0 Esterase PHB depolymerase LIP PF03583.14 KXH62035.1 - 0.036 13.4 0.1 0.39 10.0 0.0 2.0 2 0 0 2 2 2 0 Secretory lipase YjeF_N PF03853.15 KXH62035.1 - 0.08 12.8 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 YjeF-related protein N-terminus DUF829 PF05705.14 KXH62035.1 - 0.084 12.8 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF829) Glyco_trans_4_4 PF13579.6 KXH62035.1 - 0.19 12.2 2.7 8.9 6.7 0.1 2.2 2 0 0 2 2 2 0 Glycosyl transferase 4-like domain DUF2048 PF09752.9 KXH62035.1 - 0.25 10.4 0.0 0.37 9.8 0.0 1.1 1 0 0 1 1 1 0 Abhydrolase domain containing 18 Abhydrolase_2 PF02230.16 KXH62035.1 - 0.26 11.1 0.0 0.79 9.5 0.0 1.6 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Fungal_trans PF04082.18 KXH62036.1 - 5.7e-16 58.3 0.5 1.4e-15 57.1 0.4 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH62036.1 - 1.1e-06 28.6 14.2 1.8e-06 27.9 14.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BacteriocIIc_cy PF12173.8 KXH62036.1 - 0.19 12.0 0.0 0.88 9.9 0.0 2.0 2 0 0 2 2 2 0 Bacteriocin class IIc cyclic gassericin A-like p450 PF00067.22 KXH62037.1 - 1.1e-69 235.4 0.0 1.3e-69 235.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HSP70 PF00012.20 KXH62038.1 - 4.6e-59 200.1 0.0 4.8e-31 107.6 0.0 2.2 1 1 1 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 KXH62038.1 - 1.2e-06 27.6 0.0 1.6e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 MreB/Mbl protein Atg29_N PF18388.1 KXH62039.1 - 1.2e-26 92.2 0.7 2e-26 91.6 0.7 1.4 1 0 0 1 1 1 1 Atg29 N-terminal domain Phage_holin_2_4 PF16082.5 KXH62040.1 - 0.047 13.4 0.9 0.055 13.2 0.0 1.5 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like EphA2_TM PF14575.6 KXH62040.1 - 0.18 12.7 0.0 0.26 12.2 0.0 1.4 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF2371 PF10177.9 KXH62040.1 - 0.19 11.9 0.0 0.27 11.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) p450 PF00067.22 KXH62041.1 - 1.7e-63 215.0 0.0 2.2e-63 214.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_76 PF03663.14 KXH62042.1 - 3.8e-154 513.6 17.1 4.6e-154 513.4 17.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Synaptobrevin PF00957.21 KXH62043.1 - 3.7e-33 113.2 1.0 4.2e-33 113.0 1.0 1.1 1 0 0 1 1 1 1 Synaptobrevin AKNA PF12443.8 KXH62043.1 - 0.061 14.0 0.1 0.13 13.0 0.1 1.6 1 1 0 1 1 1 0 AT-hook-containing transcription factor NAT PF04768.13 KXH62044.1 - 6.1e-50 169.2 0.1 2.4e-49 167.2 0.0 2.0 2 0 0 2 2 2 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase AA_kinase PF00696.28 KXH62044.1 - 1.2e-31 110.2 0.1 2.9e-30 105.6 0.0 2.2 2 0 0 2 2 2 1 Amino acid kinase family Semialdhyde_dh PF01118.24 KXH62044.1 - 9.5e-30 103.5 0.0 2.6e-29 102.1 0.0 1.8 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 KXH62044.1 - 0.034 14.3 0.0 0.088 12.9 0.0 1.8 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Sacchrp_dh_NADP PF03435.18 KXH62044.1 - 0.17 12.2 0.0 0.36 11.1 0.0 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain HET PF06985.11 KXH62045.1 - 2.7e-12 47.3 4.7 3.3e-10 40.5 0.6 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Fasciclin PF02469.22 KXH62046.1 - 1e-41 142.1 5.5 5.2e-22 78.4 0.2 2.1 2 0 0 2 2 2 2 Fasciclin domain DUF3176 PF11374.8 KXH62048.1 - 2.2e-29 101.8 3.0 2.2e-29 101.8 3.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) NiFe_hyd_3_EhaA PF17367.2 KXH62048.1 - 0.0077 16.4 0.7 0.0077 16.4 0.7 1.7 2 0 0 2 2 2 1 NiFe-hydrogenase-type-3 Eha complex subunit A Cellulase PF00150.18 KXH62049.1 - 3.4e-14 53.0 2.0 8e-14 51.7 2.0 1.6 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) FAD_binding_4 PF01565.23 KXH62050.1 - 8e-25 87.2 2.0 2.1e-24 85.8 1.3 2.0 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 KXH62050.1 - 3.8e-10 39.7 0.0 1.8e-09 37.5 0.0 2.0 2 0 0 2 2 2 1 Berberine and berberine like RNase_Zc3h12a PF11977.8 KXH62051.1 - 0.01 15.6 0.0 0.015 15.1 0.0 1.2 1 0 0 1 1 1 0 Zc3h12a-like Ribonuclease NYN domain TALPID3 PF15324.6 KXH62051.1 - 0.16 9.6 0.3 0.21 9.2 0.3 1.1 1 0 0 1 1 1 0 Hedgehog signalling target PRIMA1 PF16101.5 KXH62051.1 - 0.92 9.6 5.0 1.3 9.0 5.0 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Metallophos PF00149.28 KXH62052.1 - 4.4e-09 37.1 3.1 3e-08 34.4 3.1 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KXH62052.1 - 1.2e-06 28.8 0.1 2e-05 24.9 0.1 2.3 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain CPSF100_C PF13299.6 KXH62052.1 - 6.2 7.0 10.1 9.8 6.3 1.1 3.3 3 0 0 3 3 3 0 Cleavage and polyadenylation factor 2 C-terminal TAL_FSA PF00923.19 KXH62053.1 - 2.6e-93 312.5 1.6 3e-93 312.3 1.6 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase MT0933_antitox PF14013.6 KXH62053.1 - 0.013 15.8 0.7 0.045 14.0 0.2 2.2 2 0 0 2 2 2 0 MT0933-like antitoxin protein SNase PF00565.17 KXH62054.1 - 1.3e-74 247.6 3.5 5e-22 78.4 0.0 5.4 5 0 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.24 KXH62054.1 - 4.2e-23 81.7 0.0 8.4e-23 80.7 0.0 1.4 1 0 0 1 1 1 1 Tudor domain SMN PF06003.12 KXH62054.1 - 6.2e-06 25.7 0.0 3.3e-05 23.3 0.0 2.1 2 0 0 2 2 2 1 Survival motor neuron protein (SMN) Sod_Cu PF00080.20 KXH62055.1 - 2.6e-45 154.1 6.9 3e-45 153.9 6.9 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) CNH PF00780.22 KXH62056.1 - 3.4e-67 227.0 0.0 5.6e-67 226.2 0.0 1.2 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.20 KXH62056.1 - 9.8e-33 113.9 0.9 1.7e-32 113.1 0.9 1.4 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.6 KXH62056.1 - 1.1e-12 48.2 0.0 4.3e-12 46.3 0.0 2.0 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 KXH62056.1 - 0.00017 22.1 0.0 0.0013 19.2 0.0 2.3 2 0 0 2 2 2 1 PH domain PH_13 PF16652.5 KXH62056.1 - 0.18 11.6 0.0 0.79 9.5 0.0 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain PH_16 PF17838.1 KXH62056.1 - 0.18 11.6 0.1 22 4.9 0.0 2.4 2 0 0 2 2 2 0 PH domain Tropomyosin PF00261.20 KXH62056.1 - 0.53 9.6 5.1 1.1 8.6 5.1 1.3 1 0 0 1 1 1 0 Tropomyosin Beta-lactamase PF00144.24 KXH62057.1 - 1.2e-31 110.2 0.5 1.7e-31 109.7 0.5 1.2 1 0 0 1 1 1 1 Beta-lactamase Pkinase PF00069.25 KXH62060.1 - 2.5e-26 92.6 0.0 3.2e-26 92.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXH62060.1 - 7.1e-14 51.7 0.0 9.9e-14 51.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXH62060.1 - 4.1e-09 35.7 0.0 6.6e-09 35.0 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KXH62060.1 - 0.00017 21.6 0.0 0.0015 18.5 0.0 2.2 1 1 0 2 2 2 1 Phosphotransferase enzyme family RabGAP-TBC PF00566.18 KXH62062.1 - 2.1e-47 161.6 0.0 3.5e-47 160.8 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_6 PF13405.6 KXH62062.1 - 1e-06 28.2 0.5 0.014 15.3 0.3 3.7 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 KXH62062.1 - 0.00019 21.8 0.2 0.0019 18.6 0.1 2.7 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 KXH62062.1 - 0.0008 18.8 1.6 0.074 12.6 0.6 3.5 3 0 0 3 3 3 1 EF hand GRAM PF02893.20 KXH62062.1 - 0.0088 15.9 0.0 0.019 14.8 0.0 1.5 1 0 0 1 1 1 1 GRAM domain EF-hand_5 PF13202.6 KXH62062.1 - 0.039 13.5 0.2 0.14 11.7 0.2 2.0 1 0 0 1 1 1 0 EF hand WSC PF01822.19 KXH62063.1 - 1.6e-16 60.2 40.9 1.4e-10 41.2 0.6 5.1 4 1 0 4 4 4 3 WSC domain BUD22 PF09073.10 KXH62063.1 - 1.9 7.7 14.3 3.1 7.0 14.3 1.2 1 0 0 1 1 1 0 BUD22 Glyco_transf_8 PF01501.20 KXH62077.1 - 3.1e-11 43.3 0.0 2.7e-10 40.3 0.0 2.0 1 1 0 1 1 1 1 Glycosyl transferase family 8 SNF2_N PF00176.23 KXH62078.1 - 2e-52 178.1 0.2 2.9e-52 177.5 0.2 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain VIGSSK PF14773.6 KXH62078.1 - 1.4e-24 86.0 2.2 1.4e-24 86.0 2.2 2.4 2 0 0 2 2 2 1 Helicase-associated putative binding domain, C-terminal Helicase_C PF00271.31 KXH62078.1 - 1.9e-19 70.1 0.0 2.6e-18 66.4 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 KXH62078.1 - 7.5e-08 31.9 0.4 3.6e-07 29.7 0.0 2.2 2 1 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 KXH62078.1 - 1.9e-07 31.2 0.0 1.7e-06 28.2 0.0 2.6 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_34 PF13872.6 KXH62078.1 - 0.023 13.6 0.7 4.9 5.9 0.1 2.5 2 0 0 2 2 2 0 P-loop containing NTP hydrolase pore-1 RNA_pol_Rpb2_5 PF04567.17 KXH62078.1 - 0.041 14.4 0.1 0.52 10.9 0.0 2.6 2 0 0 2 2 2 0 RNA polymerase Rpb2, domain 5 HILPDA PF15220.6 KXH62079.1 - 0.045 13.9 0.5 0.85 9.8 0.0 2.9 2 0 0 2 2 2 0 Hypoxia-inducible lipid droplet-associated Tweety PF04906.13 KXH62079.1 - 0.12 11.0 2.2 0.17 10.5 2.2 1.2 1 0 0 1 1 1 0 Tweety Acyl-CoA_dh_1 PF00441.24 KXH62080.1 - 4.8e-17 62.6 0.0 2.6e-16 60.2 0.0 2.1 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain AidB_N PF18158.1 KXH62080.1 - 5.6e-11 42.6 0.0 1.1e-10 41.6 0.0 1.5 1 0 0 1 1 1 1 Adaptive response protein AidB N-terminal domain Acyl-CoA_dh_M PF02770.19 KXH62080.1 - 9.6e-08 32.1 0.0 2.5e-07 30.8 0.0 1.7 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain MARVEL PF01284.23 KXH62081.1 - 3.8e-20 72.4 12.3 4.5e-20 72.1 12.3 1.1 1 0 0 1 1 1 1 Membrane-associating domain Solute_trans_a PF03619.16 KXH62081.1 - 0.082 12.4 1.8 0.16 11.5 1.8 1.5 1 1 0 1 1 1 0 Organic solute transporter Ostalpha DUF2976 PF11190.8 KXH62081.1 - 0.73 9.7 4.3 0.78 9.6 0.4 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF2976) WD40 PF00400.32 KXH62083.1 - 2.2e-21 75.7 15.5 2.3e-05 25.0 0.1 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXH62083.1 - 1.9e-11 44.1 0.7 0.0055 17.0 0.0 4.2 2 2 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KXH62083.1 - 0.0024 16.6 0.9 0.22 10.2 0.0 3.1 2 1 0 3 3 3 1 Nucleoporin Nup120/160 Hira PF07569.11 KXH62083.1 - 0.14 11.9 0.0 1.7 8.3 0.0 2.4 2 1 1 3 3 3 0 TUP1-like enhancer of split UAF_Rrn10 PF05234.11 KXH62084.1 - 0.012 15.8 0.0 0.081 13.2 0.0 2.1 1 1 0 1 1 1 0 UAF complex subunit Rrn10 Zn_clus PF00172.18 KXH62087.1 - 1.3e-08 34.9 13.1 1.9e-08 34.3 13.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BTB PF00651.31 KXH62096.1 - 2.1e-05 24.7 0.0 6.6e-05 23.1 0.0 1.8 1 1 0 1 1 1 1 BTB/POZ domain FRQ PF09421.10 KXH62097.1 - 0 1396.1 52.1 0 1395.9 52.1 1.0 1 0 0 1 1 1 1 Frequency clock protein Fungal_trans PF04082.18 KXH62098.1 - 4e-08 32.6 0.2 7e-08 31.8 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH62099.1 - 6.2e-06 26.2 6.0 1.2e-05 25.4 6.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NTP_transferase PF00483.23 KXH62134.1 - 1.6e-52 178.6 0.0 3.6e-52 177.4 0.0 1.5 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep PF00132.24 KXH62134.1 - 7.6e-18 63.5 17.7 1e-10 40.9 1.4 3.6 2 2 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 KXH62134.1 - 9.7e-12 45.5 0.0 1.3e-11 45.1 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 KXH62134.1 - 1.2e-06 28.1 5.2 2.5e-05 23.9 0.4 3.3 3 1 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 KXH62134.1 - 0.0073 14.5 0.0 0.016 13.4 0.0 1.5 1 1 1 2 2 2 1 Domain of unknown function (DUF4954) IspD PF01128.19 KXH62134.1 - 0.0081 15.9 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase CTP_transf_3 PF02348.19 KXH62134.1 - 0.01 15.8 0.0 0.031 14.2 0.0 1.7 2 0 0 2 2 2 0 Cytidylyltransferase FGGY_C PF02782.16 KXH62135.1 - 4.8e-72 241.9 0.5 8.5e-72 241.1 0.5 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 KXH62135.1 - 3e-66 223.5 0.0 4e-66 223.1 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain DUF4164 PF13747.6 KXH62153.1 - 0.037 14.3 0.2 1 9.7 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) 2OG-FeII_Oxy_2 PF13532.6 KXH62156.1 - 5.9e-30 104.9 0.0 8.8e-30 104.4 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Isochorismatase PF00857.20 KXH62156.1 - 2.5e-22 79.9 0.0 1.3e-21 77.5 0.0 2.1 2 0 0 2 2 2 1 Isochorismatase family GST_C_2 PF13410.6 KXH62156.1 - 5.8e-07 29.4 0.0 1.2e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KXH62156.1 - 3.6e-05 23.9 0.0 7.6e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KXH62156.1 - 4e-05 23.8 0.1 8e-05 22.8 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain SHMT PF00464.19 KXH62157.1 - 9.5e-196 650.1 0.0 1.1e-195 649.9 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.21 KXH62157.1 - 0.0097 15.2 0.0 0.027 13.7 0.0 1.7 1 1 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 KXH62157.1 - 0.02 14.2 0.0 0.029 13.7 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Gcn1_N PF12074.8 KXH62158.1 - 2.1e-124 415.5 12.9 3.7e-124 414.7 10.3 3.0 2 0 0 2 2 2 1 Generalcontrol nonderepressible 1 (Gcn1) N-terminal Ribosomal_L19e PF01280.20 KXH62158.1 - 3.4e-53 179.6 7.3 6.8e-35 120.2 0.7 2.7 2 0 0 2 2 2 2 Ribosomal protein L19e HEAT PF02985.22 KXH62158.1 - 1.3e-29 99.7 46.9 0.013 15.7 0.1 22.9 28 0 0 28 28 25 8 HEAT repeat HEAT_EZ PF13513.6 KXH62158.1 - 8.1e-28 96.5 52.2 1.3e-05 25.6 0.0 19.7 19 4 6 25 25 20 6 HEAT-like repeat HEAT_2 PF13646.6 KXH62158.1 - 4.6e-24 84.6 52.5 0.00011 22.5 3.9 16.0 11 4 6 19 19 18 10 HEAT repeats Cnd1 PF12717.7 KXH62158.1 - 5.9e-14 52.4 4.0 0.58 10.2 0.3 10.4 7 3 5 12 12 11 3 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 KXH62158.1 - 3e-13 50.2 0.0 0.4 11.3 0.0 9.5 7 2 3 10 10 10 2 Vacuolar 14 Fab1-binding region ParcG PF10274.9 KXH62158.1 - 4.9e-11 43.1 1.0 0.00096 19.3 0.0 6.5 4 2 2 6 6 6 2 Parkin co-regulated protein CLASP_N PF12348.8 KXH62158.1 - 1.3e-10 41.3 0.0 0.14 11.7 0.0 6.0 4 1 1 5 5 5 2 CLASP N terminal Adaptin_N PF01602.20 KXH62158.1 - 2e-07 30.0 12.7 0.15 10.6 5.1 8.3 8 2 2 10 10 10 2 Adaptin N terminal region MMS19_C PF12460.8 KXH62158.1 - 3.3e-07 29.8 14.8 0.0012 18.1 0.2 6.5 5 2 1 6 6 6 2 RNAPII transcription regulator C-terminal TIP120 PF08623.10 KXH62158.1 - 7.6e-05 22.5 2.6 0.04 13.7 0.0 5.6 6 1 0 6 6 5 1 TATA-binding protein interacting (TIP20) DUF3385 PF11865.8 KXH62158.1 - 0.00027 20.9 0.0 1.6 8.6 0.0 5.6 6 2 0 6 6 6 1 Domain of unknown function (DUF3385) DUF937 PF06078.11 KXH62158.1 - 0.00046 20.8 6.7 4.3 7.9 0.0 7.1 6 2 1 7 7 6 1 Bacterial protein of unknown function (DUF937) Ecm29 PF13001.7 KXH62158.1 - 0.00063 18.5 0.4 3.5 6.2 0.0 5.1 4 2 1 5 5 5 1 Proteasome stabiliser FANCI_S2 PF14676.6 KXH62158.1 - 0.0044 17.3 0.4 1.8 8.9 0.1 4.3 4 0 0 4 4 4 1 FANCI solenoid 2 TFCD_C PF12612.8 KXH62158.1 - 0.012 15.5 0.7 0.19 11.6 0.0 3.5 3 0 0 3 3 3 0 Tubulin folding cofactor D C terminal Tti2 PF10521.9 KXH62158.1 - 0.029 13.9 6.4 6.8 6.1 0.0 6.4 7 1 1 8 8 8 0 Tti2 family Ipi1_N PF12333.8 KXH62158.1 - 0.052 14.1 0.4 1.5 9.5 0.1 3.9 4 0 0 4 4 2 0 Rix1 complex component involved in 60S ribosome maturation RIX1 PF08167.12 KXH62158.1 - 0.3 10.8 4.2 0.68 9.6 0.2 3.7 2 1 0 2 2 2 0 rRNA processing/ribosome biogenesis HEAT_PBS PF03130.16 KXH62158.1 - 3.4 8.6 18.8 37 5.4 0.6 8.2 8 0 0 8 8 6 0 PBS lyase HEAT-like repeat HA2 PF04408.23 KXH62159.1 - 1.8e-14 53.9 0.0 1.8e-14 53.9 0.0 3.0 4 0 0 4 4 3 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KXH62159.1 - 3.5e-13 49.9 0.0 9.3e-13 48.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KXH62159.1 - 4.8e-11 42.8 0.0 9.8e-11 41.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KXH62159.1 - 6.7e-08 32.9 0.1 3e-07 30.8 0.1 2.1 1 0 0 1 1 1 1 AAA domain OB_NTP_bind PF07717.16 KXH62159.1 - 1.4e-05 25.4 0.0 2.9e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold ABC_tran PF00005.27 KXH62159.1 - 0.0045 17.5 0.1 0.023 15.2 0.0 2.2 2 0 0 2 2 2 1 ABC transporter Neuraminidase PF18413.1 KXH62159.1 - 0.024 14.3 0.2 0.024 14.3 0.2 2.1 2 0 0 2 2 2 0 Neuraminidase-like domain ATPase PF06745.13 KXH62159.1 - 0.032 13.6 0.0 0.078 12.3 0.0 1.6 1 0 0 1 1 1 0 KaiC AAA_29 PF13555.6 KXH62159.1 - 0.042 13.6 0.0 0.096 12.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain T2SSE PF00437.20 KXH62159.1 - 0.067 12.2 0.0 0.14 11.2 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein NACHT PF05729.12 KXH62159.1 - 0.092 12.7 0.2 0.45 10.4 0.0 2.2 2 0 0 2 2 2 0 NACHT domain RsgA_GTPase PF03193.16 KXH62159.1 - 0.15 12.0 0.0 0.52 10.2 0.0 1.9 2 0 0 2 2 2 0 RsgA GTPase AAA_23 PF13476.6 KXH62159.1 - 0.75 10.3 0.0 0.75 10.3 0.0 3.4 4 0 0 4 4 4 0 AAA domain RRM_1 PF00076.22 KXH62160.1 - 8.7e-44 147.2 0.1 5.4e-14 51.8 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KXH62160.1 - 1.6e-33 114.4 0.0 1.1e-26 92.5 0.0 3.6 3 0 0 3 3 3 3 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 KXH62160.1 - 2e-08 34.1 0.0 0.0018 18.2 0.0 3.4 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 KXH62160.1 - 2.8e-08 33.4 0.0 5.5e-07 29.2 0.0 2.7 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM PF05172.13 KXH62160.1 - 0.00013 21.8 0.0 0.23 11.4 0.0 2.9 1 1 1 2 2 2 2 Nup53/35/40-type RNA recognition motif TPR_14 PF13428.6 KXH62160.1 - 0.0033 18.1 1.4 0.89 10.5 0.0 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat Neur_chan_memb PF02932.16 KXH62160.1 - 1.3 9.0 3.6 3.4 7.7 3.6 1.6 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF702 PF05142.12 KXH62160.1 - 3.8 8.0 6.7 14 6.2 6.7 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF702) CFEM PF05730.11 KXH62161.1 - 1.3e-12 47.7 7.1 2e-12 47.0 7.1 1.3 1 0 0 1 1 1 1 CFEM domain SKG6 PF08693.10 KXH62161.1 - 0.00019 20.7 1.3 0.00041 19.7 1.3 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain SPX PF03105.19 KXH62161.1 - 0.38 10.6 6.4 0.48 10.3 6.4 1.2 1 0 0 1 1 1 0 SPX domain Ecl1 PF12855.7 KXH62161.1 - 1.2 10.3 24.9 1.9 9.7 24.9 1.2 1 0 0 1 1 1 0 ECL1/2/3 zinc binding proteins Ndc1_Nup PF09531.10 KXH62161.1 - 5.8 5.5 10.9 7.2 5.2 10.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Ribosomal_L22 PF00237.19 KXH62162.1 - 8.7e-20 70.9 0.1 1.8e-19 69.9 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e DUF3619 PF12279.8 KXH62162.1 - 0.44 10.9 2.4 2.6 8.4 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3619) COX6C PF02937.15 KXH62163.1 - 0.0031 17.6 0.0 0.0037 17.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIc Mitochondr_Som1 PF11093.8 KXH62164.1 - 2.7e-26 91.4 0.1 3.4e-26 91.1 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial export protein Som1 NTP_transferase PF00483.23 KXH62165.1 - 0.073 12.6 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Nucleotidyl transferase Hydrolase_6 PF13344.6 KXH62166.1 - 1.6e-23 82.7 0.0 4.2e-23 81.4 0.0 1.8 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KXH62166.1 - 5.1e-14 52.1 0.0 2.3e-13 50.0 0.0 2.2 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 KXH62166.1 - 0.0032 17.8 0.0 4.8 7.4 0.0 3.0 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase adh_short_C2 PF13561.6 KXH62167.1 - 1.8e-52 178.2 0.2 2.4e-52 177.8 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXH62167.1 - 2.9e-40 137.8 1.5 4.8e-40 137.1 1.5 1.3 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXH62167.1 - 1.1e-08 35.2 0.8 1.6e-08 34.6 0.8 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KXH62167.1 - 0.028 13.5 0.0 0.05 12.7 0.0 1.4 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein MR_MLE_C PF13378.6 KXH62168.1 - 2.8e-42 144.8 0.0 3.7e-42 144.4 0.0 1.1 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 KXH62168.1 - 1.3e-09 38.2 0.0 2.1e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Glyco_hydro_42 PF02449.15 KXH62168.1 - 0.079 12.3 0.0 0.7 9.2 0.0 2.0 2 0 0 2 2 2 0 Beta-galactosidase Fungal_trans PF04082.18 KXH62169.1 - 3.6e-26 91.8 2.3 6.8e-26 90.9 2.3 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain PBP1_TM PF14812.6 KXH62169.1 - 8 6.9 7.8 1.6 9.1 3.9 1.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Ctr PF04145.15 KXH62170.1 - 2.9e-38 131.8 0.2 3.5e-38 131.5 0.2 1.1 1 0 0 1 1 1 1 Ctr copper transporter family Ferric_reduct PF01794.19 KXH62171.1 - 1.4e-24 86.6 7.9 3.5e-24 85.3 7.9 1.7 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KXH62171.1 - 1.1e-15 58.1 0.0 1.7e-15 57.5 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KXH62171.1 - 5.5e-11 42.5 0.0 1.2e-10 41.5 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 KXH62171.1 - 8.6e-06 26.4 0.0 1.9e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Transgly_assoc PF04226.13 KXH62171.1 - 4.2 7.7 8.5 0.11 12.8 1.1 2.2 3 0 0 3 3 3 0 Transglycosylase associated protein AF-4 PF05110.13 KXH62171.1 - 6.9 4.6 5.9 9.4 4.2 5.9 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein NPP1 PF05630.11 KXH62173.1 - 1.2e-38 133.2 0.8 1.9e-37 129.3 0.8 2.0 1 1 0 1 1 1 1 Necrosis inducing protein (NPP1) HSF_DNA-bind PF00447.17 KXH62174.1 - 7.9e-31 106.5 2.5 1.6e-30 105.6 2.5 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding Response_reg PF00072.24 KXH62174.1 - 3.2e-21 75.6 0.0 7.4e-21 74.4 0.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain YabA PF06156.13 KXH62174.1 - 0.11 13.2 5.1 0.24 12.1 5.1 1.5 1 0 0 1 1 1 0 Initiation control protein YabA DUF16 PF01519.16 KXH62174.1 - 0.14 12.7 5.5 0.27 11.7 5.5 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF16 USP8_interact PF08941.10 KXH62174.1 - 0.99 9.2 4.8 1.9 8.2 4.8 1.4 1 0 0 1 1 1 0 USP8 interacting DivIC PF04977.15 KXH62174.1 - 1.1 9.1 4.2 2.1 8.2 4.2 1.5 1 0 0 1 1 1 0 Septum formation initiator SlyX PF04102.12 KXH62174.1 - 1.3 9.7 10.7 1.5 9.5 8.6 2.2 1 1 1 2 2 2 0 SlyX PHD PF00628.29 KXH62187.1 - 4.7e-09 36.0 7.7 8.1e-09 35.2 7.7 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 KXH62187.1 - 2.5e-06 26.9 3.0 4.2e-06 26.2 3.0 1.4 1 0 0 1 1 1 1 PHD-finger PHF5 PF03660.14 KXH62187.1 - 0.00077 19.6 1.7 0.0013 18.9 1.7 1.3 1 0 0 1 1 1 1 PHF5-like protein zf-PHD-like PF15446.6 KXH62187.1 - 0.0012 18.5 1.8 0.0028 17.3 1.8 1.6 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain Prok-RING_1 PF14446.6 KXH62187.1 - 0.072 13.0 2.5 0.14 12.1 2.5 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zf-rbx1 PF12678.7 KXH62187.1 - 0.51 10.7 5.8 0.56 10.5 4.2 1.9 1 1 1 2 2 2 0 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KXH62187.1 - 0.74 10.2 7.3 1.5 9.2 7.3 1.5 1 0 0 1 1 1 0 Ring finger domain MRP-L46 PF11788.8 KXH62188.1 - 6.4e-24 85.0 0.0 1.1e-23 84.3 0.0 1.4 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 NUDIX PF00293.28 KXH62188.1 - 0.019 15.0 0.2 0.045 13.8 0.2 1.6 1 1 0 1 1 1 0 NUDIX domain RPA PF10134.9 KXH62188.1 - 0.084 12.3 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Replication initiator protein A Rxt3 PF08642.10 KXH62216.1 - 1.9e-44 151.5 0.0 4.4e-44 150.3 0.0 1.7 1 0 0 1 1 1 1 Histone deacetylation protein Rxt3 LCCL PF03815.19 KXH62216.1 - 0.00078 19.5 0.0 0.01 16.0 0.0 2.2 2 0 0 2 2 2 1 LCCL domain DUF1674 PF07896.12 KXH62217.1 - 1.5e-18 67.0 2.2 1.5e-18 67.0 2.2 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1674) DUF5569 PF17729.1 KXH62217.1 - 0.13 12.1 1.4 0.17 11.8 1.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5569) SSP160 PF06933.11 KXH62217.1 - 4.4 5.4 10.5 5.1 5.2 10.5 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Glyco_hydro_43 PF04616.14 KXH62218.1 - 1.2e-31 110.1 1.8 1.4e-31 109.9 1.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 DUF763 PF05559.11 KXH62220.1 - 0.29 10.3 0.0 0.29 10.3 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF763) Whib PF02467.16 KXH62220.1 - 3.2 8.4 8.1 23 5.7 3.7 3.4 2 1 2 4 4 4 0 Transcription factor WhiB SPO22 PF08631.10 KXH62229.1 - 1.4e-73 247.8 0.3 6.2e-70 235.8 0.0 3.3 3 0 0 3 3 3 2 Meiosis protein SPO22/ZIP4 like Sel1 PF08238.12 KXH62229.1 - 0.025 15.3 0.2 3.2 8.6 0.0 3.3 3 0 0 3 3 3 0 Sel1 repeat TPR_2 PF07719.17 KXH62229.1 - 0.057 13.5 1.3 6.7 7.1 0.2 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat PAS PF00989.25 KXH62229.1 - 0.094 12.7 0.1 0.41 10.7 0.0 2.1 2 0 0 2 2 2 0 PAS fold TPR_19 PF14559.6 KXH62229.1 - 0.31 11.6 2.0 1.5 9.4 2.0 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat Pyridoxal_deC PF00282.19 KXH62230.1 - 4.7e-77 259.2 0.0 6.1e-77 258.8 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 KXH62230.1 - 1.8e-07 30.4 0.0 2.9e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KXH62230.1 - 0.015 14.6 0.7 0.043 13.1 0.1 1.9 2 1 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family DUF4431 PF14485.6 KXH62230.1 - 0.12 12.2 0.0 0.39 10.5 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4431) Yip1 PF04893.17 KXH62232.1 - 5.7e-12 45.7 17.2 8e-12 45.2 17.0 1.4 1 1 0 1 1 1 1 Yip1 domain DUF1282 PF06930.12 KXH62232.1 - 0.044 13.6 4.9 0.076 12.8 4.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) Ran_BP1 PF00638.18 KXH62233.1 - 1.6e-11 44.5 0.1 0.0002 21.6 0.0 2.5 2 0 0 2 2 2 2 RanBP1 domain SDA1 PF05285.12 KXH62233.1 - 6.3 6.1 33.4 0.38 10.1 6.4 2.1 2 0 0 2 2 2 0 SDA1 DEAD PF00270.29 KXH62234.1 - 1.6e-28 99.7 0.0 3.7e-28 98.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1998 PF09369.10 KXH62234.1 - 1.3e-20 73.9 0.2 3.9e-20 72.4 0.2 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) Helicase_C PF00271.31 KXH62234.1 - 1.4e-11 44.7 0.0 7e-11 42.5 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXH62234.1 - 3.4e-07 30.4 0.0 7.1e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CDT1 PF08839.11 KXH62234.1 - 3.5e-06 27.4 0.2 8.9e-06 26.1 0.2 1.8 1 1 0 1 1 1 1 DNA replication factor CDT1 like TMCO5 PF14992.6 KXH62234.1 - 0.07 12.7 0.1 0.16 11.6 0.1 1.5 1 0 0 1 1 1 0 TMCO5 family Na_Ca_ex PF01699.24 KXH62236.1 - 6.9e-27 94.3 25.7 2.2e-13 50.4 6.9 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein 7tm_7 PF08395.12 KXH62236.1 - 0.039 13.2 0.0 0.039 13.2 0.0 2.6 2 1 2 4 4 4 0 7tm Chemosensory receptor DUF4536 PF15055.6 KXH62236.1 - 0.046 14.0 2.8 0.054 13.8 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4536) DUF1298 PF06974.13 KXH62236.1 - 0.14 12.1 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1298) DUF5337 PF17272.2 KXH62236.1 - 0.18 11.7 1.2 1.3 8.9 0.1 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5337) Na_Ala_symp PF01235.17 KXH62236.1 - 2.3 7.4 13.1 1 8.6 0.2 3.1 2 1 0 3 3 3 0 Sodium:alanine symporter family Mo-co_dimer PF03404.16 KXH62237.1 - 1.4e-60 203.3 0.1 2.7e-60 202.3 0.1 1.5 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Oxidored_molyb PF00174.19 KXH62237.1 - 2.1e-55 187.0 0.0 3.4e-55 186.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain FAD_binding_6 PF00970.24 KXH62237.1 - 9.1e-34 115.8 0.0 1.8e-33 114.8 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 KXH62237.1 - 2.5e-23 82.8 0.0 6.6e-23 81.4 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.28 KXH62237.1 - 2.3e-14 53.3 0.0 6.1e-14 51.9 0.0 1.8 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 KXH62237.1 - 0.012 15.8 0.0 0.076 13.1 0.0 2.1 2 0 0 2 2 2 0 Ferric reductase NAD binding domain MIF4G PF02854.19 KXH62238.1 - 8.1e-59 198.8 0.0 1.3e-31 109.9 0.0 3.5 3 1 0 3 3 3 2 MIF4G domain Upf2 PF04050.14 KXH62238.1 - 3.7e-39 134.6 6.8 3.7e-39 134.6 6.8 2.8 2 0 0 2 2 2 1 Up-frameshift suppressor 2 Nop14 PF04147.12 KXH62238.1 - 0.0029 15.9 13.9 0.0078 14.5 13.9 1.7 1 0 0 1 1 1 1 Nop14-like family CDC45 PF02724.14 KXH62238.1 - 0.0043 15.4 6.9 0.0098 14.2 6.9 1.5 1 0 0 1 1 1 1 CDC45-like protein Astro_capsid_p PF12226.8 KXH62238.1 - 0.032 13.4 10.1 0.072 12.2 10.1 1.5 1 0 0 1 1 1 0 Turkey astrovirus capsid protein CBP4 PF07960.11 KXH62238.1 - 0.06 13.2 0.0 0.06 13.2 0.0 2.4 3 0 0 3 3 3 0 CBP4 TGS PF02824.21 KXH62238.1 - 0.14 12.2 1.9 0.34 11.0 0.0 2.6 3 0 0 3 3 3 0 TGS domain TCTP PF00838.17 KXH62238.1 - 4.4 7.6 5.9 1.6 9.0 0.5 2.9 3 0 0 3 3 3 0 Translationally controlled tumour protein DUF349 PF03993.12 KXH62238.1 - 6.2 7.2 8.8 24 5.3 5.2 3.3 2 1 0 2 2 2 0 Domain of Unknown Function (DUF349) Chitin_synth_2 PF03142.15 KXH62239.1 - 5.2e-25 88.1 7.8 2.1e-24 86.1 2.6 2.9 3 0 0 3 3 3 2 Chitin synthase Glyco_trans_2_3 PF13632.6 KXH62239.1 - 3.6e-16 59.7 4.4 3.6e-16 59.7 4.4 2.4 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KXH62239.1 - 1.6e-12 47.8 0.0 3.4e-12 46.8 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KXH62239.1 - 0.0026 17.6 0.2 0.4 10.5 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferase family 2 HSP70 PF00012.20 KXH62240.1 - 6.4e-163 543.1 6.9 6.4e-163 543.1 6.9 2.5 1 1 1 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 KXH62240.1 - 9.4e-14 50.9 0.2 8.6e-13 47.8 0.0 2.2 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 KXH62240.1 - 0.0038 17.6 6.6 0.073 13.5 0.1 3.1 3 1 0 3 3 3 2 Cell division protein FtsA GTP_EFTU PF00009.27 KXH62241.1 - 3.7e-33 114.7 3.1 3.9e-33 114.6 0.0 2.7 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 KXH62241.1 - 1.1e-19 70.5 0.0 3e-19 69.1 0.0 1.8 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D4 PF14578.6 KXH62241.1 - 5.7e-08 32.6 1.3 3.8e-07 29.9 1.3 2.4 1 1 0 1 1 1 1 Elongation factor Tu domain 4 GTP_EFTU_D2 PF03144.25 KXH62241.1 - 1.4e-07 31.8 9.5 3e-07 30.7 0.1 3.3 3 0 0 3 3 3 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KXH62241.1 - 6e-07 29.5 0.1 1.4e-05 25.1 0.0 3.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase Roc PF08477.13 KXH62241.1 - 0.0013 19.0 0.0 0.0038 17.4 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 KXH62241.1 - 0.021 14.6 0.0 0.021 14.6 0.0 2.4 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 KXH62241.1 - 2.8 7.8 4.6 5.6 6.8 0.2 3.4 2 1 1 3 3 3 0 RsgA GTPase RabGAP-TBC PF00566.18 KXH62243.1 - 4.4e-19 69.0 0.0 6.5e-19 68.4 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Vps52 PF04129.12 KXH62244.1 - 3.2e-126 422.1 0.0 4.2e-126 421.7 0.0 1.0 1 0 0 1 1 1 1 Vps52 / Sac2 family Sec3_C PF09763.9 KXH62244.1 - 4.3e-06 25.4 1.7 3.1e-05 22.6 1.8 1.9 1 1 0 1 1 1 1 Exocyst complex component Sec3 Exo70 PF03081.15 KXH62244.1 - 0.0072 15.4 0.0 0.017 14.2 0.0 1.6 1 0 0 1 1 1 1 Exo70 exocyst complex subunit Filament PF00038.21 KXH62244.1 - 0.21 11.1 3.6 0.89 9.1 0.0 2.6 3 0 0 3 3 3 0 Intermediate filament protein eIF-5a PF01287.20 KXH62245.1 - 2.3e-27 94.9 1.6 3.3e-27 94.4 1.6 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 KXH62245.1 - 0.0038 17.2 0.1 0.02 14.9 0.0 2.1 2 0 0 2 2 2 1 Elongation factor P (EF-P) KOW-like domain zf-RRN7 PF11781.8 KXH62246.1 - 1.7e-05 24.4 0.6 2.9e-05 23.6 0.6 1.4 1 0 0 1 1 1 1 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Yip1 PF04893.17 KXH62247.1 - 2.2e-11 43.8 16.9 2.2e-11 43.8 16.9 1.4 1 1 0 1 1 1 1 Yip1 domain Rhodanese PF00581.20 KXH62248.1 - 3.4e-13 50.0 0.0 5.3e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain p450 PF00067.22 KXH62249.1 - 1e-49 169.5 0.0 1.9e-49 168.7 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 Phage_T7_Capsid PF05396.11 KXH62249.1 - 0.065 13.6 0.0 0.21 11.9 0.0 1.8 2 0 0 2 2 2 0 Phage T7 capsid assembly protein SR-25 PF10500.9 KXH62250.1 - 0.026 14.1 36.6 0.037 13.7 36.6 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF4228 PF14009.6 KXH62250.1 - 0.26 11.7 11.7 0.32 11.4 11.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) Apt1 PF10351.9 KXH62250.1 - 2.2 7.1 20.8 2.4 6.9 20.8 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain DLIC PF05783.11 KXH62250.1 - 5.1 5.8 10.7 5.7 5.6 10.7 1.0 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) DUF572 PF04502.13 KXH62250.1 - 6.5 6.3 11.8 7.4 6.1 11.8 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) DASH_Ask1 PF08655.10 KXH62251.1 - 5.2e-31 106.3 0.3 8e-31 105.7 0.3 1.3 1 0 0 1 1 1 1 DASH complex subunit Ask1 DUF3073 PF11273.8 KXH62251.1 - 1 10.2 3.8 0.77 10.6 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3073) GCP_C_terminal PF04130.13 KXH62252.1 - 1.5e-80 271.0 0.0 5.7e-79 265.8 0.0 2.1 2 0 0 2 2 2 2 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 KXH62252.1 - 3.6e-31 108.9 0.1 5.8e-31 108.3 0.1 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal DUF3510 PF12022.8 KXH62252.1 - 0.038 14.4 0.0 0.11 12.8 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3510) Eaf7 PF07904.13 KXH62253.1 - 3.4e-26 91.7 0.2 3.4e-26 91.7 0.2 2.4 2 1 0 2 2 2 1 Chromatin modification-related protein EAF7 Myb_DNA-binding PF00249.31 KXH62254.1 - 0.054 13.7 1.1 0.2 11.8 0.0 2.6 3 0 0 3 3 3 0 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KXH62254.1 - 0.065 13.1 1.2 0.8 9.6 0.0 2.8 3 0 0 3 3 3 0 Myb DNA-binding like ResIII PF04851.15 KXH62255.1 - 1.3e-26 93.6 0.0 5.1e-26 91.7 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KXH62255.1 - 6.3e-17 61.9 0.1 3e-15 56.5 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KXH62255.1 - 1.6e-12 47.6 0.0 2.6e-11 43.6 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 KXH62255.1 - 4.6e-06 26.5 0.0 1e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 SWI2/SNF2 ATPase ERCC3_RAD25_C PF16203.5 KXH62255.1 - 0.00024 20.4 0.0 0.00041 19.6 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase DUF2075 PF09848.9 KXH62255.1 - 0.0062 15.8 0.0 0.012 14.9 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) UvrD-helicase PF00580.21 KXH62255.1 - 0.075 12.5 0.1 6.5 6.2 0.0 2.5 1 1 1 2 2 2 0 UvrD/REP helicase N-terminal domain T2SSE PF00437.20 KXH62255.1 - 0.079 12.0 0.0 0.15 11.1 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Helicase_C_2 PF13307.6 KXH62255.1 - 0.08 13.1 0.1 1.1 9.4 0.0 2.5 2 0 0 2 2 2 0 Helicase C-terminal domain SwrA PF17423.2 KXH62255.1 - 0.082 12.9 0.0 0.21 11.6 0.0 1.7 1 0 0 1 1 1 0 Swarming motility protein AAA_22 PF13401.6 KXH62255.1 - 0.14 12.4 0.0 0.67 10.2 0.0 2.1 1 1 0 1 1 1 0 AAA domain KH_1 PF00013.29 KXH62256.1 - 2.9e-30 103.9 1.0 3.5e-07 30.0 0.0 7.6 8 0 0 8 8 8 5 KH domain Xpo1 PF08389.12 KXH62257.1 - 6.9e-37 126.8 0.1 6.9e-37 126.8 0.1 3.2 3 1 0 3 3 3 1 Exportin 1-like protein HEAT PF02985.22 KXH62257.1 - 0.004 17.3 0.0 13 6.4 0.0 4.0 3 0 0 3 3 3 2 HEAT repeat HNOB PF07700.15 KXH62257.1 - 0.018 15.0 0.3 0.94 9.4 0.0 3.3 3 1 1 4 4 4 0 Haem-NO-binding Prefoldin_2 PF01920.20 KXH62257.1 - 0.1 12.6 0.2 12 5.9 0.0 2.7 2 0 0 2 2 2 0 Prefoldin subunit Vps39_2 PF10367.9 KXH62271.1 - 2.4e-07 31.1 0.0 5.9e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.9 KXH62271.1 - 0.011 16.0 0.0 0.043 14.1 0.0 2.0 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 CASP_C PF08172.12 KXH62272.1 - 4e-96 321.2 12.8 7e-94 313.9 0.0 3.8 3 1 2 5 5 5 1 CASP C terminal TolA_bind_tri PF16331.5 KXH62272.1 - 0.0048 16.9 32.2 0.23 11.6 0.2 6.1 6 0 0 6 6 6 2 TolA binding protein trimerisation bZIP_2 PF07716.15 KXH62272.1 - 0.0053 16.8 1.4 0.0053 16.8 1.4 7.7 8 1 0 8 8 8 2 Basic region leucine zipper DUF4164 PF13747.6 KXH62272.1 - 0.0074 16.5 1.1 0.0074 16.5 1.1 5.8 5 1 0 5 5 5 1 Domain of unknown function (DUF4164) ADIP PF11559.8 KXH62272.1 - 0.0087 16.2 7.0 0.0087 16.2 7.0 6.6 3 1 4 7 7 7 2 Afadin- and alpha -actinin-Binding SlyX PF04102.12 KXH62272.1 - 0.015 15.9 0.0 0.015 15.9 0.0 6.7 7 0 0 7 7 7 0 SlyX Filament PF00038.21 KXH62272.1 - 0.041 13.5 48.7 0.14 11.8 4.4 3.9 3 1 2 5 5 5 0 Intermediate filament protein CENP-H PF05837.12 KXH62272.1 - 0.12 12.8 0.2 0.12 12.8 0.2 6.0 5 1 1 6 6 6 0 Centromere protein H (CENP-H) DUF1664 PF07889.12 KXH62272.1 - 0.16 12.0 0.1 0.16 12.0 0.1 5.8 5 1 1 6 6 5 0 Protein of unknown function (DUF1664) DUF4407 PF14362.6 KXH62272.1 - 0.3 10.4 33.6 1.6 8.0 10.8 4.5 2 1 2 4 4 4 0 Domain of unknown function (DUF4407) GTP-bdg_M PF16360.5 KXH62272.1 - 0.35 11.5 0.0 0.35 11.5 0.0 5.5 4 1 1 5 5 4 0 GTP-binding GTPase Middle Region Metal_resist PF13801.6 KXH62272.1 - 0.47 10.6 0.0 0.47 10.6 0.0 3.6 4 0 0 4 4 3 0 Heavy-metal resistance PI3K_P85_iSH2 PF16454.5 KXH62272.1 - 0.57 9.8 37.5 0.14 11.7 5.4 4.9 3 1 2 5 5 5 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain ZapB PF06005.12 KXH62272.1 - 0.59 10.6 0.1 0.59 10.6 0.1 6.5 4 2 2 6 6 6 0 Cell division protein ZapB Fez1 PF06818.15 KXH62272.1 - 0.77 10.2 47.5 2.1 8.8 4.0 4.7 3 1 2 5 5 5 0 Fez1 IFP_35_N PF07334.13 KXH62272.1 - 0.96 9.6 0.0 0.96 9.6 0.0 4.5 5 0 0 5 5 4 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus YabA PF06156.13 KXH62272.1 - 1.7 9.4 37.1 1.7 9.3 0.0 6.1 2 1 3 6 6 6 0 Initiation control protein YabA APG6_N PF17675.1 KXH62272.1 - 2.1 8.9 61.8 4.1 7.9 0.2 5.8 2 1 3 5 5 5 0 Apg6 coiled-coil region TPR_MLP1_2 PF07926.12 KXH62272.1 - 2.9 8.0 63.6 0.8 9.8 8.5 6.8 4 1 2 6 6 6 0 TPR/MLP1/MLP2-like protein DUF2400 PF09674.10 KXH62272.1 - 3.2 7.7 8.0 0.68 9.9 0.3 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2400) Fib_alpha PF08702.10 KXH62272.1 - 3.5 7.8 36.2 2 8.6 7.2 4.9 5 0 0 5 5 5 0 Fibrinogen alpha/beta chain family WD40_alt PF14077.6 KXH62272.1 - 4 7.4 7.7 10 6.1 0.0 4.2 3 1 1 4 4 4 0 Alternative WD40 repeat motif SKA1 PF07160.12 KXH62272.1 - 6 6.7 27.0 10 5.9 0.0 4.5 3 1 1 4 4 4 0 Spindle and kinetochore-associated protein 1 FlaC_arch PF05377.11 KXH62272.1 - 6.9 7.2 35.9 0.47 10.9 0.2 6.9 6 1 1 7 7 7 0 Flagella accessory protein C (FlaC) Med1 PF10744.9 KXH62280.1 - 3e-126 421.8 0.0 3.7e-126 421.5 0.0 1.1 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription subunit 1 KilA-N PF04383.13 KXH62281.1 - 0.00082 19.2 0.0 0.011 15.6 0.0 2.2 1 1 0 1 1 1 1 KilA-N domain adh_short_C2 PF13561.6 KXH62283.1 - 0.19 11.2 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase F-box-like PF12937.7 KXH62284.1 - 2.4e-09 37.0 0.0 5.3e-09 35.8 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXH62284.1 - 0.016 15.1 0.0 0.036 13.9 0.0 1.6 1 0 0 1 1 1 0 F-box domain ASFV_J13L PF05568.11 KXH62284.1 - 0.097 12.4 0.7 0.18 11.5 0.7 1.4 1 0 0 1 1 1 0 African swine fever virus J13L protein Mito_carr PF00153.27 KXH62285.1 - 2.7e-61 203.5 4.4 1.4e-20 73.0 0.1 4.1 3 1 0 3 3 3 3 Mitochondrial carrier protein UDG PF03167.19 KXH62286.1 - 2.5e-23 82.8 0.0 5.1e-23 81.8 0.0 1.4 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily RhgB_N PF09284.10 KXH62287.1 - 4.9e-85 285.1 1.0 6.8e-85 284.6 1.0 1.2 1 0 0 1 1 1 1 Rhamnogalacturonan lyase B, N-terminal CBM-like PF14683.6 KXH62287.1 - 8.1e-33 113.6 0.1 8.1e-33 113.6 0.1 2.6 4 1 0 4 4 4 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.6 KXH62287.1 - 1.5e-17 63.1 4.4 4.4e-17 61.6 4.4 1.8 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.6 KXH62287.1 - 0.0008 19.6 1.7 0.0012 19.0 0.4 2.0 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain Cupin_5 PF06172.11 KXH62287.1 - 0.14 12.3 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 Cupin superfamily (DUF985) Vps8 PF12816.7 KXH62288.1 - 2.2e-74 249.3 0.1 4.6e-74 248.2 0.1 1.6 1 0 0 1 1 1 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.20 KXH62288.1 - 3.6e-05 23.7 0.0 0.058 13.3 0.0 3.0 2 0 0 2 2 2 2 Region in Clathrin and VPS zf-RING_5 PF14634.6 KXH62288.1 - 0.008 16.1 0.0 0.008 16.1 0.0 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KXH62288.1 - 0.032 14.3 0.2 0.079 13.0 0.2 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_11 PF17123.5 KXH62288.1 - 0.065 13.0 0.1 0.13 12.0 0.1 1.5 1 0 0 1 1 1 0 RING-like zinc finger zf-rbx1 PF12678.7 KXH62288.1 - 0.088 13.1 0.0 0.21 11.9 0.0 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3H2C3 PF17122.5 KXH62288.1 - 0.12 12.4 0.2 0.3 11.1 0.2 1.6 1 0 0 1 1 1 0 Zinc-finger zf-RING_2 PF13639.6 KXH62288.1 - 0.21 12.0 0.1 0.21 12.0 0.1 1.9 2 0 0 2 2 2 0 Ring finger domain PHD PF00628.29 KXH62288.1 - 5.9 6.9 5.9 0.9 9.5 0.3 2.4 2 0 0 2 2 2 0 PHD-finger DUF3752 PF12572.8 KXH62289.1 - 2e-50 171.2 11.1 4.3e-50 170.2 11.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3752) zf-RING_2 PF13639.6 KXH62290.1 - 2.2e-11 43.9 6.8 3.4e-11 43.3 6.8 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KXH62290.1 - 7.1e-08 32.1 1.3 1.1e-07 31.4 1.3 1.3 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KXH62290.1 - 7.7e-08 32.1 6.4 1.2e-07 31.4 6.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXH62290.1 - 1e-07 31.7 4.2 1.6e-07 31.0 4.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KXH62290.1 - 5.1e-06 26.7 9.8 2.6e-05 24.4 9.8 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KXH62290.1 - 1.3e-05 25.0 3.8 2e-05 24.4 3.8 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 KXH62290.1 - 0.0016 18.4 1.7 0.0033 17.4 1.7 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 KXH62290.1 - 0.0034 17.2 2.7 0.0052 16.6 2.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXH62290.1 - 0.0037 17.2 1.0 0.0037 17.2 1.0 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_4 PF14570.6 KXH62290.1 - 0.019 14.8 6.6 0.032 14.0 6.6 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 KXH62290.1 - 0.22 11.4 4.7 0.45 10.4 4.7 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 PHD PF00628.29 KXH62290.1 - 0.25 11.3 5.8 0.43 10.5 5.8 1.4 1 0 0 1 1 1 0 PHD-finger FANCL_C PF11793.8 KXH62290.1 - 0.46 10.7 3.2 1.2 9.4 3.2 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 KXH62290.1 - 0.62 9.7 4.8 1.1 9.0 4.8 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-UDP PF14569.6 KXH62290.1 - 0.68 10.1 3.8 0.75 10.0 0.6 2.4 2 0 0 2 2 2 0 Zinc-binding RING-finger OAD_gamma PF04277.13 KXH62290.1 - 1 10.0 0.0 1 10.0 0.0 3.3 3 1 0 3 3 2 0 Oxaloacetate decarboxylase, gamma chain zf-C3HC4_4 PF15227.6 KXH62290.1 - 1.1 9.4 4.7 2.4 8.4 4.7 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING RNase_PH PF01138.21 KXH62292.1 - 3.8e-16 59.8 0.0 7.7e-16 58.8 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KXH62292.1 - 0.00012 22.0 0.1 0.00021 21.3 0.1 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 PTPA PF03095.15 KXH62293.1 - 6.4e-113 377.2 0.0 7.8e-113 376.9 0.0 1.1 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein K_channel_TID PF07941.11 KXH62295.1 - 0.34 11.4 2.6 0.85 10.1 1.7 1.9 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain HAD PF12710.7 KXH62297.1 - 6.7e-16 59.2 0.1 1.2e-14 55.1 0.0 2.5 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KXH62297.1 - 0.049 13.9 0.2 0.95 9.7 0.2 2.1 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KXH62297.1 - 0.068 13.3 0.3 15 5.7 0.1 3.1 2 2 0 2 2 2 0 Haloacid dehalogenase-like hydrolase TFIIF_beta_N PF17683.1 KXH62298.1 - 3.3e-32 112.0 0.5 7.7e-32 110.8 0.1 1.8 2 0 0 2 2 2 1 TFIIF, beta subunit N-terminus TFIIF_beta PF02270.15 KXH62298.1 - 5.5e-23 80.9 0.3 1e-22 80.0 0.3 1.5 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain Elongin_A PF06881.11 KXH62299.1 - 1.1e-28 99.8 2.0 2.2e-28 98.9 2.0 1.4 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A Macoilin PF09726.9 KXH62299.1 - 0.71 8.4 5.3 0.97 7.9 5.3 1.3 1 0 0 1 1 1 0 Macoilin family Band_7 PF01145.25 KXH62300.1 - 2.8e-23 82.9 2.6 5.5e-23 81.9 2.6 1.5 1 0 0 1 1 1 1 SPFH domain / Band 7 family ubiquitin PF00240.23 KXH62300.1 - 6.9e-18 64.2 0.1 1.4e-17 63.2 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KXH62300.1 - 1e-06 28.4 0.0 2.4e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KXH62300.1 - 0.025 15.0 0.0 0.073 13.5 0.0 1.7 1 1 0 1 1 1 0 Ubiquitin-like domain Trehalase PF01204.18 KXH62301.1 - 1.8e-117 393.3 8.0 1.3e-116 390.5 8.0 1.9 1 1 0 1 1 1 1 Trehalase GDE_C PF06202.14 KXH62301.1 - 2.4e-05 23.4 0.2 7.1e-05 21.9 0.0 1.7 2 0 0 2 2 2 1 Amylo-alpha-1,6-glucosidase RFX5_N PF18326.1 KXH62301.1 - 0.02 14.6 0.1 0.21 11.4 0.0 2.5 3 0 0 3 3 3 0 RFX5 N-terminal domain Beta_elim_lyase PF01212.21 KXH62302.1 - 1.1e-68 231.6 0.0 1.4e-68 231.4 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 KXH62302.1 - 3.7e-05 23.1 0.0 4.5e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KXH62302.1 - 6e-05 21.8 0.0 0.00011 20.8 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 KXH62302.1 - 0.0015 17.9 0.6 0.0054 16.1 0.6 1.9 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Glyco_transf_17 PF04724.13 KXH62303.1 - 3.1e-51 174.5 0.1 1.5e-50 172.2 0.1 2.0 1 1 0 1 1 1 1 Glycosyltransferase family 17 Arf PF00025.21 KXH62304.1 - 2e-44 151.1 0.1 2.4e-44 150.9 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 KXH62304.1 - 8.7e-21 74.2 0.0 1e-20 74.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXH62304.1 - 2.5e-16 60.0 0.0 3.6e-16 59.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 KXH62304.1 - 6e-08 32.3 0.0 7.8e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KXH62304.1 - 3.1e-07 30.4 0.0 4.5e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 KXH62304.1 - 3.9e-06 26.3 0.1 1.3e-05 24.6 0.0 1.9 1 1 1 2 2 2 1 G-protein alpha subunit SRPRB PF09439.10 KXH62304.1 - 8.1e-06 25.4 0.0 9.8e-06 25.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 KXH62304.1 - 0.0042 16.7 0.0 0.021 14.4 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 KXH62304.1 - 0.0068 16.5 0.1 0.55 10.3 0.1 2.1 1 1 1 2 2 2 1 Dynamin family FeoB_N PF02421.18 KXH62304.1 - 0.034 13.7 0.4 0.067 12.7 0.4 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B ATP_bind_1 PF03029.17 KXH62304.1 - 0.062 13.1 0.0 0.099 12.4 0.0 1.3 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein PduV-EutP PF10662.9 KXH62304.1 - 0.083 12.6 0.1 2.5 7.8 0.0 2.5 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1_Xtn PF16897.5 KXH62304.1 - 0.12 12.4 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain DUF1979 PF09322.10 KXH62304.1 - 0.17 11.8 0.4 9.8 6.2 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1979) TRAM_LAG1_CLN8 PF03798.16 KXH62313.1 - 4.2e-36 124.5 19.7 7.1e-36 123.8 19.7 1.4 1 0 0 1 1 1 1 TLC domain TRAM1 PF08390.11 KXH62313.1 - 1.4e-25 88.7 1.6 5.1e-25 86.9 0.0 2.4 2 0 0 2 2 2 1 TRAM1-like protein ABC_tran PF00005.27 KXH62314.1 - 2.4e-32 112.3 0.1 1.1e-31 110.1 0.0 2.1 2 0 0 2 2 2 1 ABC transporter ABC_membrane PF00664.23 KXH62314.1 - 1.6e-29 103.5 8.2 1.6e-29 103.5 8.2 1.9 2 0 0 2 2 2 1 ABC transporter transmembrane region SMC_N PF02463.19 KXH62314.1 - 3.2e-06 26.8 0.0 2.2e-05 24.0 0.0 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KXH62314.1 - 0.013 15.5 0.0 0.029 14.3 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 KXH62314.1 - 0.059 13.1 0.1 0.23 11.2 0.1 2.0 1 0 0 1 1 1 0 P-loop containing region of AAA domain 4HB_MCP_1 PF12729.7 KXH62314.1 - 0.06 12.9 1.1 0.12 11.9 1.1 1.4 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction Forkhead PF00250.18 KXH62319.1 - 0.014 15.6 0.3 0.025 14.8 0.3 1.4 1 0 0 1 1 1 0 Forkhead domain Zn_clus PF00172.18 KXH62319.1 - 0.034 14.3 3.3 0.12 12.6 3.4 1.9 1 1 1 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain RAD51_interact PF15696.5 KXH62319.1 - 0.055 13.6 0.1 0.18 11.9 0.1 1.9 1 0 0 1 1 1 0 RAD51 interacting motif AltA1 PF16541.5 KXH62341.1 - 0.045 14.6 0.0 0.26 12.2 0.0 1.9 1 1 1 2 2 2 0 Alternaria alternata allergen 1 Helo_like_N PF17111.5 KXH62343.1 - 7e-10 38.6 0.2 1.6e-09 37.4 0.2 1.6 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins Ank_2 PF12796.7 KXH62343.1 - 1.3e-05 25.7 1.0 0.014 16.0 0.1 4.3 3 1 1 4 4 4 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXH62343.1 - 0.0069 16.7 0.9 19 5.7 0.0 4.2 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXH62343.1 - 0.16 12.6 1.2 43 4.8 0.1 4.0 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Ank PF00023.30 KXH62343.1 - 0.19 12.2 8.8 14 6.3 0.1 5.8 6 1 1 7 7 7 0 Ankyrin repeat CHASE3 PF05227.13 KXH62343.1 - 0.2 11.5 1.5 0.4 10.6 0.4 2.0 2 0 0 2 2 2 0 CHASE3 domain DUF3431 PF11913.8 KXH62344.1 - 1.9e-15 57.2 0.1 4.2e-15 56.1 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3431) Dehydratase_hem PF13816.6 KXH62344.1 - 0.16 11.4 0.0 0.53 9.6 0.0 1.7 2 0 0 2 2 2 0 Haem-containing dehydratase FMO-like PF00743.19 KXH62353.1 - 3.3e-12 45.6 0.0 1.4e-10 40.3 0.0 2.4 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KXH62353.1 - 1.3e-10 41.4 0.0 5.5e-10 39.3 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KXH62353.1 - 3.5e-08 33.1 0.2 3.3e-07 29.9 0.1 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXH62353.1 - 3.6e-07 29.7 0.0 1.5e-05 24.4 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXH62353.1 - 6.3e-06 25.6 0.1 0.00031 20.0 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 KXH62353.1 - 0.00072 18.9 0.0 0.0037 16.5 0.0 2.0 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.6 KXH62353.1 - 0.0022 18.0 0.5 0.55 10.2 0.0 3.4 3 1 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.24 KXH62353.1 - 0.029 14.0 0.3 5.6 6.4 0.0 2.6 2 1 0 2 2 2 0 FAD dependent oxidoreductase OmdA PF13376.6 KXH62353.1 - 2 8.5 4.3 3 7.9 0.4 3.1 3 1 0 3 3 3 0 Bacteriocin-protection, YdeI or OmpD-Associated MFS_1 PF07690.16 KXH62354.1 - 1.6e-08 33.9 33.2 1.6e-08 33.9 33.2 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 KXH62354.1 - 3.4e-06 26.9 3.6 3.4e-06 26.9 3.6 3.0 3 0 0 3 3 3 2 Ion channel regulatory protein UNC-93 Bac_luciferase PF00296.20 KXH62355.1 - 8.8e-58 196.2 1.2 1.2e-57 195.7 1.2 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase AcetylCoA_hydro PF02550.15 KXH62356.1 - 1.2e-49 169.0 0.0 1.9e-49 168.4 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.6 KXH62356.1 - 2.5e-43 147.7 0.0 3.6e-43 147.2 0.0 1.2 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain UDPGT PF00201.18 KXH62357.1 - 1.5e-15 57.0 0.0 2e-13 50.0 0.0 2.0 2 0 0 2 2 2 2 UDP-glucoronosyl and UDP-glucosyl transferase NEMO PF11577.8 KXH62359.1 - 0.068 13.2 1.0 0.15 12.1 0.4 1.8 2 0 0 2 2 2 0 NF-kappa-B essential modulator NEMO FlaC_arch PF05377.11 KXH62359.1 - 0.26 11.7 0.4 0.49 10.8 0.4 1.4 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) DivIC PF04977.15 KXH62359.1 - 1.2 9.0 4.0 2.1 8.1 1.9 2.2 2 0 0 2 2 2 0 Septum formation initiator bZIP_1 PF00170.21 KXH62359.1 - 2 8.6 7.8 4.9 7.3 7.8 1.6 1 1 0 1 1 1 0 bZIP transcription factor adh_short PF00106.25 KXH62360.1 - 7.3e-27 94.1 0.1 1e-26 93.6 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXH62360.1 - 2.6e-21 76.3 1.0 4.8e-21 75.4 1.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH62360.1 - 7.8e-15 55.2 0.4 1.7e-14 54.2 0.4 1.5 1 1 0 1 1 1 1 KR domain PAC2 PF09754.9 KXH62360.1 - 0.0026 17.8 0.1 0.0044 17.1 0.1 1.3 1 0 0 1 1 1 1 PAC2 family Polysacc_synt_2 PF02719.15 KXH62360.1 - 0.066 12.3 0.0 0.077 12.1 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein ThiF PF00899.21 KXH62360.1 - 0.16 11.3 1.7 3.3 7.0 0.3 2.1 2 0 0 2 2 2 0 ThiF family DUF3799 PF12684.7 KXH62360.1 - 0.21 11.3 0.2 0.58 9.9 0.2 1.8 1 1 0 1 1 1 0 PDDEXK-like domain of unknown function (DUF3799) PHF12_MRG_bd PF16737.5 KXH62361.1 - 0.06 13.1 0.2 0.17 11.6 0.2 1.8 1 0 0 1 1 1 0 PHD finger protein 12 MRG binding domain Hydrophobin_2 PF06766.11 KXH62362.1 - 1.1e-12 47.7 10.2 1.8e-12 47.0 10.2 1.3 1 0 0 1 1 1 1 Fungal hydrophobin Hydrophobin PF01185.18 KXH62362.1 - 0.0087 16.7 0.3 0.0087 16.7 0.3 1.8 2 0 0 2 2 2 1 Fungal hydrophobin MFS_1 PF07690.16 KXH62363.1 - 6.6e-16 58.2 22.4 7.5e-15 54.7 16.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.16 KXH62363.1 - 1.6e-08 34.4 2.0 5.8e-08 32.6 2.0 2.0 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 EGF_2 PF07974.13 KXH62364.1 - 0.00025 21.3 10.4 0.0005 20.4 10.4 1.5 1 0 0 1 1 1 1 EGF-like domain Nodulin_late PF07127.11 KXH62364.1 - 0.018 15.4 0.2 0.04 14.3 0.2 1.6 1 0 0 1 1 1 0 Late nodulin protein hEGF PF12661.7 KXH62364.1 - 0.27 11.9 3.9 0.58 10.9 3.9 1.6 1 0 0 1 1 1 0 Human growth factor-like EGF EB PF01683.18 KXH62364.1 - 0.6 10.4 5.7 1.2 9.4 5.7 1.4 1 0 0 1 1 1 0 EB module Pectate_lyase PF03211.13 KXH62365.1 - 1.2e-59 201.3 2.3 1.4e-59 201.1 2.3 1.0 1 0 0 1 1 1 1 Pectate lyase Fungal_trans_2 PF11951.8 KXH62366.1 - 4e-11 42.3 3.3 4.2e-09 35.7 0.7 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH62366.1 - 1.6e-06 28.1 8.0 2.9e-06 27.3 8.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.24 KXH62367.1 - 2.6e-76 257.3 29.2 3.2e-76 257.0 29.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH62367.1 - 1.6e-26 93.1 57.9 8.6e-25 87.4 37.8 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily US6 PF17616.2 KXH62367.1 - 0.16 11.9 0.1 0.38 10.7 0.1 1.6 1 0 0 1 1 1 0 Viral unique short region 6 Mem_trans PF03547.18 KXH62367.1 - 5.2 5.3 17.4 0.017 13.5 2.1 3.0 2 1 1 3 3 3 0 Membrane transport protein ThiS-like PF14453.6 KXH62368.1 - 0.038 14.0 0.0 0.066 13.3 0.0 1.4 1 0 0 1 1 1 0 ThiS-like ubiquitin PCO_ADO PF07847.12 KXH62368.1 - 0.075 12.5 0.0 0.082 12.4 0.0 1.1 1 0 0 1 1 1 0 PCO_ADO VPS9 PF02204.18 KXH62369.1 - 6.6e-18 64.8 0.1 1.4e-17 63.8 0.1 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ank_5 PF13857.6 KXH62369.1 - 6.7e-17 61.3 0.1 4.6e-12 45.9 0.0 4.4 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXH62369.1 - 6.8e-13 49.0 0.4 0.00022 21.7 0.0 4.3 3 1 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXH62369.1 - 9.7e-09 35.6 0.7 0.17 12.5 0.0 6.0 5 1 0 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXH62369.1 - 4.6e-07 29.6 0.3 0.28 11.9 0.0 5.3 5 0 0 5 5 5 2 Ankyrin repeat Ank PF00023.30 KXH62369.1 - 0.00054 20.3 0.0 1.3 9.6 0.0 4.4 4 0 0 4 4 4 1 Ankyrin repeat PX PF00787.24 KXH62369.1 - 0.16 11.9 0.0 0.68 9.9 0.0 2.1 1 0 0 1 1 1 0 PX domain NAD_binding_1 PF00175.21 KXH62371.1 - 4.5e-29 101.3 0.0 8.5e-29 100.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KXH62371.1 - 2.1e-14 53.7 0.0 3.7e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 KXH62371.1 - 5.7e-07 29.8 0.1 0.0031 17.7 0.0 2.7 2 1 1 3 3 3 2 Ferric reductase NAD binding domain ProRS-C_1 PF09180.11 KXH62371.1 - 0.19 12.0 0.0 0.34 11.1 0.0 1.3 1 0 0 1 1 1 0 Prolyl-tRNA synthetase, C-terminal DUF1593 PF07632.11 KXH62373.1 - 2.3e-83 279.6 0.0 3e-83 279.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1593) REJ PF02010.15 KXH62373.1 - 7.8e-05 21.6 0.0 0.00012 21.0 0.0 1.2 1 0 0 1 1 1 1 REJ domain Fungal_trans PF04082.18 KXH62374.1 - 1.9e-05 23.9 0.0 3.9e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain TPR_10 PF13374.6 KXH62374.1 - 0.1 12.5 0.1 28 4.7 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-C2H2 PF00096.26 KXH62431.1 - 0.00015 22.1 14.5 0.0012 19.2 4.2 3.7 2 1 0 2 2 2 2 Zinc finger, C2H2 type FOXP-CC PF16159.5 KXH62431.1 - 0.024 15.3 0.5 0.024 15.3 0.5 3.5 3 1 1 4 4 4 0 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 KXH62431.1 - 0.036 14.9 3.2 0.036 14.9 3.2 4.0 4 0 0 4 4 4 0 C2H2-type zinc finger YdjO PF14169.6 KXH62431.1 - 0.076 12.8 0.1 5.8 6.7 0.1 2.6 2 0 0 2 2 2 0 Cold-inducible protein YdjO IBR PF01485.21 KXH62431.1 - 0.17 12.1 2.7 2.7 8.3 2.5 2.4 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain LRR_6 PF13516.6 KXH62432.1 - 0.005 16.8 2.1 0.92 9.7 0.0 3.4 3 0 0 3 3 3 2 Leucine Rich repeat LRR_4 PF12799.7 KXH62432.1 - 0.25 11.9 7.2 12 6.5 0.0 5.1 6 1 1 7 7 7 0 Leucine Rich repeats (2 copies) Glyco_hydro_12 PF01670.16 KXH62433.1 - 5.8e-48 163.7 10.9 7.1e-48 163.4 10.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 Phage_holin_5_1 PF06946.11 KXH62433.1 - 0.027 14.8 3.7 0.2 12.0 2.0 2.4 2 1 0 2 2 2 0 Bacteriophage A118-like holin, Hol118 PPV_E2_C PF00511.17 KXH62433.1 - 7.3 6.8 8.8 23 5.2 0.3 2.5 1 1 1 2 2 2 0 E2 (early) protein, C terminal FAD_binding_4 PF01565.23 KXH62434.1 - 5.6e-20 71.5 4.1 8e-20 71.0 2.1 2.1 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 KXH62434.1 - 5.7e-05 23.1 0.1 0.00012 22.2 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like YqhR PF11085.8 KXH62435.1 - 0.089 12.7 1.7 0.26 11.2 0.9 2.2 1 1 1 2 2 2 0 Conserved membrane protein YqhR IgGFc_binding PF17517.2 KXH62436.1 - 0.021 14.1 0.0 0.028 13.7 0.0 1.2 1 0 0 1 1 1 0 IgGFc binding protein Auxin_BP PF02041.16 KXH62436.1 - 0.061 13.0 0.0 0.085 12.5 0.0 1.2 1 0 0 1 1 1 0 Auxin binding protein ThuA PF06283.11 KXH62437.1 - 1.8e-46 159.0 1.9 5.1e-45 154.3 1.9 2.0 1 1 0 1 1 1 1 Trehalose utilisation LysM PF01476.20 KXH62438.1 - 2.3e-20 72.4 1.6 3.7e-07 30.1 0.2 3.3 3 0 0 3 3 3 3 LysM domain SBE2 PF17076.5 KXH62438.1 - 0.072 11.3 0.3 0.091 11.0 0.3 1.1 1 0 0 1 1 1 0 SBE2, cell-wall formation UPF0203 PF05254.12 KXH62438.1 - 0.13 12.5 3.9 4.8 7.5 0.4 2.6 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0203) Mucin PF01456.17 KXH62438.1 - 0.62 10.1 29.3 0.21 11.6 22.0 2.3 2 0 0 2 2 2 0 Mucin-like glycoprotein Glyco_hydro_18 PF00704.28 KXH62440.1 - 5.8e-46 157.7 0.4 1.4e-45 156.4 0.4 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 Hce2 PF14856.6 KXH62440.1 - 1.1e-27 96.3 1.0 3.1e-27 94.9 1.0 1.9 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor LysM PF01476.20 KXH62440.1 - 1e-05 25.5 0.0 0.28 11.3 0.0 3.3 3 0 0 3 3 3 2 LysM domain Chitin_bind_1 PF00187.19 KXH62440.1 - 2e-05 24.9 8.6 2e-05 24.9 8.6 3.7 2 1 0 2 2 2 1 Chitin recognition protein OPT PF03169.15 KXH62442.1 - 5.1e-161 537.4 52.8 5.8e-161 537.2 52.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein 3HCDH_N PF02737.18 KXH62443.1 - 2.1e-27 96.1 0.0 3.5e-27 95.4 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 KXH62443.1 - 7.6e-13 48.9 0.0 1.4e-12 48.0 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Sox17_18_mid PF12067.8 KXH62443.1 - 0.12 12.5 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 Sox 17/18 central domain AlaDh_PNT_C PF01262.21 KXH62443.1 - 0.16 11.3 0.0 6.4 6.0 0.0 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain IlvN PF07991.12 KXH62443.1 - 0.18 11.4 0.0 1.1 8.8 0.0 2.0 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Histidinol_dh PF00815.20 KXH62444.1 - 1.6e-137 458.9 0.0 1.9e-137 458.6 0.0 1.0 1 0 0 1 1 1 1 Histidinol dehydrogenase FlbD PF06289.11 KXH62444.1 - 0.13 11.9 0.0 0.42 10.3 0.0 1.8 1 0 0 1 1 1 0 Flagellar and Swarming motility proteins Fungal_trans PF04082.18 KXH62445.1 - 0.024 13.7 0.2 0.047 12.7 0.2 1.5 1 0 0 1 1 1 0 Fungal specific transcription factor domain Acyl_transf_3 PF01757.22 KXH62446.1 - 4.9e-28 98.2 28.8 2.7e-27 95.7 28.8 2.0 1 1 0 1 1 1 1 Acyltransferase family DUF3176 PF11374.8 KXH62447.1 - 8e-31 106.4 4.1 8e-31 106.4 4.1 2.1 3 0 0 3 3 3 1 Protein of unknown function (DUF3176) PRIMA1 PF16101.5 KXH62447.1 - 0.46 10.5 5.0 0.94 9.5 5.0 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Dioxygenase_C PF00775.21 KXH62448.1 - 2e-39 134.9 0.0 2.8e-39 134.4 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 KXH62448.1 - 6.1e-26 90.1 0.0 9.3e-26 89.5 0.0 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus SpaA PF17802.1 KXH62448.1 - 0.00096 19.4 0.1 0.0027 18.0 0.1 1.7 1 0 0 1 1 1 1 Prealbumin-like fold domain CarboxypepD_reg PF13620.6 KXH62448.1 - 0.073 13.3 0.0 0.35 11.2 0.0 2.1 1 1 0 1 1 1 0 Carboxypeptidase regulatory-like domain adh_short PF00106.25 KXH62449.1 - 8.3e-47 159.2 1.2 1.1e-46 158.8 1.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXH62449.1 - 9.1e-35 120.3 0.3 1.1e-34 120.0 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH62449.1 - 1.2e-09 38.4 0.1 2.2e-09 37.5 0.1 1.4 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KXH62449.1 - 0.0005 19.3 1.3 0.0013 18.0 1.3 1.7 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.20 KXH62449.1 - 0.0011 19.0 0.3 0.0025 17.9 0.3 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.21 KXH62449.1 - 0.0012 18.4 1.3 0.095 12.1 0.3 2.4 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KXH62449.1 - 0.0031 17.4 0.7 0.037 13.9 0.7 2.1 1 1 0 1 1 1 1 NAD(P)H-binding ADH_zinc_N PF00107.26 KXH62449.1 - 0.0067 16.4 0.4 0.023 14.7 0.2 2.0 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ApbA PF02558.16 KXH62449.1 - 0.085 12.5 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DLH PF01738.18 KXH62450.1 - 1.3e-17 64.1 0.0 1.7e-17 63.7 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 KXH62450.1 - 0.0084 16.7 0.2 0.04 14.5 0.2 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KXH62450.1 - 0.13 11.7 0.2 0.74 9.3 0.0 1.9 1 1 1 2 2 2 0 Prolyl oligopeptidase family NmrA PF05368.13 KXH62451.1 - 1.2e-28 100.3 0.0 1.5e-28 99.9 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXH62451.1 - 4.3e-13 49.6 0.0 1.3e-12 48.0 0.0 1.8 1 1 1 2 2 2 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KXH62451.1 - 0.00097 19.4 0.1 0.0027 18.0 0.0 1.7 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 KXH62451.1 - 0.022 15.2 0.1 0.045 14.2 0.1 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.12 KXH62451.1 - 0.13 11.4 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein DapB_N PF01113.20 KXH62451.1 - 0.15 12.2 0.1 0.25 11.5 0.1 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus MFS_1 PF07690.16 KXH62452.1 - 8.1e-29 100.6 31.2 8.1e-29 100.6 31.2 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily DEAD PF00270.29 KXH62453.1 - 9.5e-17 61.3 0.0 1.9e-16 60.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KXH62453.1 - 8.3e-13 48.7 0.0 2e-12 47.5 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KXH62453.1 - 7.8e-06 26.2 0.3 3.1e-05 24.3 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain PhoH PF02562.16 KXH62453.1 - 0.033 13.6 0.0 0.073 12.5 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein Pyr_redox_2 PF07992.14 KXH62454.1 - 1.1e-18 67.5 0.0 4.7e-15 55.6 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXH62454.1 - 2e-12 47.2 0.3 1.4e-08 34.8 0.2 2.7 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KXH62454.1 - 9.1e-11 41.6 0.0 6.9e-08 32.1 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXH62454.1 - 8.2e-08 31.8 0.1 0.00024 20.4 0.0 2.3 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KXH62454.1 - 8.6e-07 29.1 0.3 0.3 11.1 0.0 3.5 3 0 0 3 3 3 2 FAD-NAD(P)-binding FMO-like PF00743.19 KXH62454.1 - 3.8e-06 25.6 0.0 0.00025 19.6 0.0 2.2 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like DAO PF01266.24 KXH62454.1 - 1.5e-05 24.8 8.3 0.013 15.1 0.9 3.7 2 2 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 KXH62454.1 - 5.4e-05 23.7 0.9 0.17 12.4 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXH62454.1 - 0.0005 19.4 1.4 0.091 12.0 0.1 2.7 3 0 0 3 3 3 2 Thi4 family GIDA PF01134.22 KXH62454.1 - 0.001 18.2 4.0 0.53 9.3 0.0 3.0 3 0 0 3 3 3 2 Glucose inhibited division protein A FAD_binding_2 PF00890.24 KXH62454.1 - 0.0011 18.2 2.0 0.0028 16.8 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 KXH62454.1 - 0.0039 16.6 0.1 0.0086 15.5 0.1 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KXH62454.1 - 0.0098 14.6 1.9 1.6 7.3 0.2 3.0 3 0 0 3 3 3 1 HI0933-like protein ThiF PF00899.21 KXH62454.1 - 0.017 14.5 0.2 3.8 6.8 0.0 2.3 2 0 0 2 2 2 0 ThiF family Lycopene_cycl PF05834.12 KXH62454.1 - 0.017 14.2 1.8 0.21 10.6 0.1 3.1 3 1 0 3 3 3 0 Lycopene cyclase protein NAD_binding_7 PF13241.6 KXH62454.1 - 0.023 15.1 0.0 0.9 10.0 0.0 2.8 3 0 0 3 3 3 0 Putative NAD(P)-binding Semialdhyde_dh PF01118.24 KXH62454.1 - 0.025 15.0 0.0 0.2 12.1 0.0 2.3 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 KXH62454.1 - 0.028 13.8 0.0 0.049 13.0 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KXH62454.1 - 0.043 13.9 0.1 0.19 11.8 0.0 2.0 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 KXH62454.1 - 0.045 13.0 0.3 0.44 9.7 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain bZIP_1 PF00170.21 KXH62456.1 - 1.8e-08 34.3 12.6 3.7e-08 33.3 12.6 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KXH62456.1 - 0.00033 20.7 11.1 0.00033 20.7 11.1 2.3 2 0 0 2 2 2 1 Basic region leucine zipper DivIC PF04977.15 KXH62456.1 - 0.046 13.5 15.1 0.079 12.7 2.5 2.6 2 0 0 2 2 2 0 Septum formation initiator GMC_oxred_N PF00732.19 KXH62457.1 - 1.8e-58 198.2 0.0 2.9e-58 197.6 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXH62457.1 - 7.7e-34 117.3 0.0 1.7e-33 116.2 0.0 1.6 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KXH62457.1 - 7.3e-06 25.3 0.0 0.00049 19.3 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.6 KXH62457.1 - 7.3e-05 22.2 0.2 0.037 13.3 0.1 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXH62457.1 - 0.00029 21.0 0.0 0.00074 19.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXH62457.1 - 0.0022 17.7 0.1 0.099 12.2 0.0 2.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KXH62457.1 - 0.0025 16.9 0.1 0.0039 16.3 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_3 PF01494.19 KXH62457.1 - 0.016 14.5 0.0 0.024 13.9 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 KXH62457.1 - 0.06 12.0 0.0 0.087 11.5 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.17 KXH62457.1 - 0.11 11.7 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 Thi4 family TrkA_N PF02254.18 KXH62457.1 - 0.13 12.5 0.0 0.26 11.6 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Ribonucleas_3_3 PF14622.6 KXH62458.1 - 6.6e-10 39.2 0.0 1.1e-09 38.6 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 KXH62458.1 - 3.3e-07 30.9 0.1 2.9e-06 27.8 0.1 2.2 1 1 0 1 1 1 1 Ribonuclease III domain His_Me_b4a2 PF18275.1 KXH62460.1 - 0.36 10.9 1.9 0.81 9.8 1.9 1.6 1 0 0 1 1 1 0 His-Me finger endonuclease beta4-alpha2 domain Amidase PF01425.21 KXH62461.1 - 1.6e-30 106.5 0.0 2.4e-30 105.9 0.0 1.2 1 0 0 1 1 1 1 Amidase adh_short PF00106.25 KXH62461.1 - 7.2e-20 71.3 0.0 1.3e-17 63.9 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXH62461.1 - 2.7e-09 36.9 0.0 4.5e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH62461.1 - 1.3e-06 28.4 0.0 2.5e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 KR domain Sugar_tr PF00083.24 KXH62462.1 - 7.2e-105 351.4 19.5 8.3e-105 351.3 19.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH62462.1 - 2e-32 112.5 33.5 2.2e-28 99.2 16.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_5 PF05631.14 KXH62462.1 - 1.6e-06 27.3 1.7 1.6e-06 27.3 1.7 1.9 3 0 0 3 3 3 1 Sugar-tranasporters, 12 TM Phage_holin_3_2 PF04550.12 KXH62462.1 - 2.2 8.9 9.6 0.21 12.1 2.9 2.8 3 0 0 3 3 3 0 Phage holin family 2 Bac_rhamnosid6H PF17389.2 KXH62463.1 - 3.1e-91 306.2 0.5 4e-91 305.8 0.5 1.1 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_N PF08531.10 KXH62463.1 - 9.7e-51 172.0 0.0 1.5e-50 171.4 0.0 1.3 1 0 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain Bac_rhamnosid PF05592.11 KXH62463.1 - 3.6e-18 65.4 0.0 1.2e-17 63.8 0.0 1.9 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase concanavalin-like domain Bac_rhamnosid_C PF17390.2 KXH62463.1 - 7.8e-17 60.8 0.3 2.3e-16 59.3 0.1 1.9 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase C-terminal domain DUF2914 PF11141.8 KXH62463.1 - 0.43 10.4 2.4 7.4 6.4 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2914) Aldedh PF00171.22 KXH62464.1 - 1.5e-176 587.5 1.6 1.8e-176 587.2 1.6 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KXH62464.1 - 0.046 13.2 0.0 1.4 8.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) Alpha-amylase PF00128.24 KXH62465.1 - 2.8e-24 86.3 6.2 6.4e-24 85.1 6.2 1.4 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.16 KXH62465.1 - 3.1e-07 29.0 2.4 0.097 10.8 0.1 3.1 3 0 0 3 3 3 3 Glycosyl hydrolase family 70 DUF1939 PF09154.10 KXH62465.1 - 0.023 14.9 0.3 0.1 12.7 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1939) Peptidase_S8 PF00082.22 KXH62466.1 - 1.3e-27 96.9 6.0 1.3e-27 96.9 6.0 1.8 2 1 0 2 2 2 1 Subtilase family Inhibitor_I9 PF05922.16 KXH62466.1 - 6.5e-10 39.5 0.0 1.2e-09 38.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 FMN_bind PF04205.14 KXH62466.1 - 0.013 16.0 2.4 0.034 14.7 2.4 1.7 1 0 0 1 1 1 0 FMN-binding domain NAD_binding_2 PF03446.15 KXH62467.1 - 1.8e-30 106.2 0.8 2.9e-30 105.5 0.8 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KXH62467.1 - 3.2e-08 33.8 0.4 7.3e-08 32.7 0.0 1.7 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase MerR_2 PF13591.6 KXH62467.1 - 0.091 12.6 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 MerR HTH family regulatory protein MFS_1 PF07690.16 KXH62468.1 - 1e-19 70.7 13.4 1.4e-19 70.3 13.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans_2 PF11951.8 KXH62469.1 - 6.7e-18 64.7 1.8 8.8e-18 64.3 0.7 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH62469.1 - 9.7e-12 44.8 6.2 1.8e-11 43.9 5.7 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldolase_II PF00596.21 KXH62470.1 - 1.1e-48 165.7 0.0 1.3e-48 165.4 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain DUF3148 PF11347.8 KXH62470.1 - 0.085 12.6 0.0 0.47 10.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3148) Amino_oxidase PF01593.24 KXH62472.1 - 1.1e-55 189.8 0.1 1.3e-55 189.5 0.1 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Ribonuc_L-PSP PF01042.21 KXH62472.1 - 1.1e-15 57.8 0.0 1.9e-15 56.9 0.0 1.4 1 0 0 1 1 1 1 Endoribonuclease L-PSP NAD_binding_8 PF13450.6 KXH62472.1 - 2.6e-14 53.2 0.1 7.1e-14 51.8 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KXH62472.1 - 5.1e-10 39.0 0.1 1.4e-09 37.6 0.2 1.6 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 KXH62472.1 - 7.9e-09 35.0 0.3 6.6e-06 25.4 0.4 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein DAO PF01266.24 KXH62472.1 - 6.4e-07 29.3 0.0 1.3e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KXH62472.1 - 8e-07 28.8 0.1 1.3e-06 28.1 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KXH62472.1 - 1.6e-06 27.5 0.1 2.9e-06 26.7 0.1 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 KXH62472.1 - 7.4e-06 25.4 1.0 1.1e-05 24.8 1.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KXH62472.1 - 1.8e-05 24.1 0.1 5.4e-05 22.6 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXH62472.1 - 7.1e-05 21.7 0.4 0.00021 20.1 0.2 1.8 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.6 KXH62472.1 - 9e-05 21.9 1.7 0.0012 18.2 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KXH62472.1 - 0.00079 18.6 0.5 0.0019 17.3 0.5 1.6 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.27 KXH62472.1 - 0.0054 17.3 0.8 0.014 16.0 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KXH62472.1 - 0.0065 15.8 0.1 0.016 14.5 0.1 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain DUF3723 PF12520.8 KXH62482.1 - 2e-77 261.0 0.2 9.9e-76 255.4 0.2 2.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3723) DUF908 PF06012.12 KXH62495.1 - 0.29 10.5 7.8 0.43 9.9 7.8 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) CRC_subunit PF08624.10 KXH62499.1 - 3.4e-53 179.7 0.0 5.2e-53 179.1 0.0 1.3 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit Nop14 PF04147.12 KXH62499.1 - 0.19 9.9 18.5 0.27 9.4 18.5 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 KXH62499.1 - 0.3 9.3 12.4 0.43 8.8 12.4 1.2 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 KXH62499.1 - 0.57 9.6 18.6 0.99 8.8 18.6 1.3 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 KXH62499.1 - 3.8 6.8 18.3 6.1 6.1 18.3 1.3 1 0 0 1 1 1 0 BUD22 Vfa1 PF08432.10 KXH62499.1 - 4.1 7.7 13.1 33 4.7 0.1 2.3 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Paf1 PF03985.13 KXH62499.1 - 8.4 5.3 21.7 14 4.6 21.7 1.2 1 0 0 1 1 1 0 Paf1 TFIIB PF00382.19 KXH62500.1 - 1.4e-42 143.5 1.4 2.2e-23 82.1 0.0 2.2 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 KXH62500.1 - 2.2e-14 52.7 1.8 4e-14 51.9 1.8 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_C PF02984.19 KXH62500.1 - 2.2e-05 24.5 0.0 0.098 12.8 0.1 2.4 2 1 0 2 2 2 2 Cyclin, C-terminal domain RB_B PF01857.20 KXH62500.1 - 0.0067 16.5 0.0 0.032 14.3 0.0 1.9 1 1 0 2 2 2 1 Retinoblastoma-associated protein B domain Trp_repressor PF01371.19 KXH62500.1 - 0.0088 16.2 0.0 5.7 7.1 0.0 2.5 2 0 0 2 2 2 2 Trp repressor protein HTH_Tnp_ISL3 PF13542.6 KXH62500.1 - 0.011 15.1 0.1 0.27 10.7 0.0 2.6 2 1 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 Sigma70_r4_2 PF08281.12 KXH62500.1 - 0.022 14.4 0.0 0.074 12.7 0.0 1.9 1 0 0 1 1 1 0 Sigma-70, region 4 YceG PF02618.16 KXH62500.1 - 0.029 14.0 0.1 0.099 12.2 0.1 1.7 1 1 0 1 1 1 0 YceG-like family zf-ribbon_3 PF13248.6 KXH62500.1 - 0.057 12.9 1.4 0.79 9.2 0.0 2.6 2 0 0 2 2 2 0 zinc-ribbon domain Sigma70_r4 PF04545.16 KXH62500.1 - 0.1 12.1 0.0 0.7 9.5 0.0 2.3 3 0 0 3 3 3 0 Sigma-70, region 4 PAPA-1 PF04795.12 KXH62501.1 - 0.12 13.2 1.7 0.27 12.1 1.7 1.6 1 0 0 1 1 1 0 PAPA-1-like conserved region CitMHS PF03600.16 KXH62502.1 - 2.7e-13 49.8 2.2 5.6e-13 48.7 2.2 1.5 1 0 0 1 1 1 1 Citrate transporter ArsB PF02040.15 KXH62502.1 - 1.1e-12 48.0 15.7 1.1e-08 34.9 5.4 2.2 2 0 0 2 2 2 2 Arsenical pump membrane protein CEND1 PF15677.5 KXH62502.1 - 9.1 6.8 10.5 0.58 10.7 0.3 2.3 2 0 0 2 2 2 0 Cell cycle exit and neuronal differentiation protein 1 CoA_transf_3 PF02515.17 KXH62504.1 - 5.5e-124 414.0 0.0 6.3e-124 413.8 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III PHD PF00628.29 KXH62505.1 - 0.00019 21.2 5.2 0.00033 20.5 5.2 1.4 1 0 0 1 1 1 1 PHD-finger DUF2397 PF09660.10 KXH62506.1 - 0.4 9.5 1.0 0.55 9.1 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2397) DUF3176 PF11374.8 KXH62508.1 - 7e-34 116.2 1.0 7e-34 116.2 1.0 3.4 3 0 0 3 3 3 1 Protein of unknown function (DUF3176) MFS_1 PF07690.16 KXH62508.1 - 3.2e-22 78.9 44.4 6.9e-16 58.1 17.3 3.7 3 1 1 4 4 4 3 Major Facilitator Superfamily MFS_1_like PF12832.7 KXH62508.1 - 1.7e-06 27.1 13.8 0.0015 17.5 2.8 2.4 2 0 0 2 2 2 2 MFS_1 like family Sugar_tr PF00083.24 KXH62508.1 - 8.7e-06 24.9 4.9 8.7e-06 24.9 4.9 2.5 2 0 0 2 2 2 1 Sugar (and other) transporter Asn_synthase PF00733.21 KXH62509.1 - 5.6e-20 72.3 1.6 3.3e-09 36.9 0.1 3.2 2 1 1 3 3 3 3 Asparagine synthase GATase_7 PF13537.6 KXH62509.1 - 2.3e-07 30.7 0.0 1.4e-06 28.2 0.0 2.3 1 1 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 KXH62509.1 - 0.00045 20.4 0.0 0.0011 19.2 0.0 1.6 1 1 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 KXH62509.1 - 0.00092 18.7 0.0 0.0015 18.0 0.0 1.2 1 0 0 1 1 1 1 Aluminium induced protein 3HCDH_N PF02737.18 KXH62510.1 - 1.5e-26 93.3 0.0 2.7e-26 92.5 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 KXH62510.1 - 2.5e-14 53.7 0.0 3.9e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain AlaDh_PNT_C PF01262.21 KXH62510.1 - 0.15 11.4 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.14 KXH62510.1 - 0.16 11.2 0.0 0.24 10.6 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 KXH62510.1 - 0.17 11.2 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain BTB PF00651.31 KXH62511.1 - 0.00044 20.5 0.0 0.00074 19.7 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Peptidase_M28 PF04389.17 KXH62513.1 - 6.8e-35 120.5 0.0 9.2e-35 120.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 MFS_1 PF07690.16 KXH62514.1 - 5.8e-24 84.7 33.8 2.3e-23 82.7 33.8 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH62514.1 - 5.7e-06 25.5 9.6 5.7e-06 25.5 9.6 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter HSP70 PF00012.20 KXH62515.1 - 2e-13 49.4 0.0 4.8e-12 44.9 0.0 2.0 2 0 0 2 2 2 2 Hsp70 protein ATG19_autophagy PF12744.7 KXH62515.1 - 0.12 11.6 0.1 0.22 10.7 0.1 1.4 1 0 0 1 1 1 0 Autophagy protein Atg19, Atg8-binding PilM_2 PF11104.8 KXH62515.1 - 0.16 10.9 0.0 0.27 10.2 0.0 1.2 1 0 0 1 1 1 0 Type IV pilus assembly protein PilM; BcrAD_BadFG PF01869.20 KXH62515.1 - 0.21 11.1 0.0 6.2 6.2 0.0 2.3 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Not3 PF04065.15 KXH62516.1 - 0.001 18.6 3.5 0.003 17.0 3.5 1.7 1 1 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component DUF2408 PF10303.9 KXH62516.1 - 0.0068 17.0 1.8 0.013 16.0 1.8 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2408) DUF1664 PF07889.12 KXH62516.1 - 0.013 15.5 2.1 0.44 10.6 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Atg14 PF10186.9 KXH62516.1 - 0.015 14.4 3.3 0.023 13.8 3.3 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 APG6_N PF17675.1 KXH62516.1 - 0.077 13.5 14.1 0.14 12.7 14.1 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region TSC22 PF01166.18 KXH62516.1 - 0.087 13.2 0.6 0.087 13.2 0.6 2.3 2 0 0 2 2 2 0 TSC-22/dip/bun family Phage_GPO PF05929.11 KXH62516.1 - 0.11 12.1 2.4 0.17 11.5 2.4 1.4 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase V_ATPase_I PF01496.19 KXH62516.1 - 0.13 10.1 0.5 0.14 10.0 0.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FapA PF03961.13 KXH62516.1 - 0.2 10.2 2.7 0.29 9.7 2.7 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Prefoldin PF02996.17 KXH62516.1 - 0.22 11.4 6.8 3.6 7.5 1.0 2.5 2 0 0 2 2 2 0 Prefoldin subunit Tropomyosin PF00261.20 KXH62516.1 - 0.24 10.8 15.7 0.097 12.0 12.7 1.7 1 1 1 2 2 2 0 Tropomyosin DUF4795 PF16043.5 KXH62516.1 - 0.35 10.4 7.9 2 8.0 7.8 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) Exonuc_VII_L PF02601.15 KXH62516.1 - 0.54 9.8 3.0 0.78 9.2 3.0 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Herpes_BLRF2 PF05812.12 KXH62516.1 - 0.55 10.4 4.6 1.9 8.7 4.6 1.9 1 1 0 1 1 1 0 Herpesvirus BLRF2 protein DUF5082 PF16888.5 KXH62516.1 - 0.81 10.0 5.4 1.8 8.9 5.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) TMF_TATA_bd PF12325.8 KXH62516.1 - 0.88 9.8 10.6 2.2 8.5 10.4 1.8 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding RF-1 PF00472.20 KXH62516.1 - 0.89 9.5 3.1 2.2 8.2 3.0 1.7 1 1 0 1 1 1 0 RF-1 domain FlaC_arch PF05377.11 KXH62516.1 - 0.97 9.9 2.9 37 4.8 0.1 2.9 3 0 0 3 3 2 0 Flagella accessory protein C (FlaC) Nup54 PF13874.6 KXH62516.1 - 1.4 9.0 7.0 3 8.0 7.0 1.5 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 GAS PF13851.6 KXH62516.1 - 1.5 8.1 11.7 2.9 7.2 11.7 1.5 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding COG2 PF06148.11 KXH62516.1 - 1.6 8.8 4.5 5.3 7.1 0.7 2.3 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Prefoldin_2 PF01920.20 KXH62516.1 - 3.2 7.7 8.2 3.3e+02 1.3 8.2 2.6 1 1 0 1 1 1 0 Prefoldin subunit XhlA PF10779.9 KXH62516.1 - 3.4 8.0 5.1 16 5.8 0.1 2.6 2 0 0 2 2 2 0 Haemolysin XhlA TMPIT PF07851.13 KXH62516.1 - 3.7 6.7 4.4 6.1 6.0 4.4 1.4 1 0 0 1 1 1 0 TMPIT-like protein ERM PF00769.19 KXH62516.1 - 4.2 7.1 16.4 6.4 6.5 16.4 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Spc7 PF08317.11 KXH62516.1 - 6.2 5.6 13.9 16 4.2 13.9 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF4407 PF14362.6 KXH62516.1 - 6.9 5.9 8.4 11 5.2 8.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) MFS_1 PF07690.16 KXH62517.1 - 9e-35 120.2 44.5 2.6e-30 105.6 40.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KXH62517.1 - 0.0025 17.2 21.8 0.0058 16.0 21.8 1.5 1 1 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB CorA PF01544.18 KXH62518.1 - 0.004 16.5 0.0 0.004 16.5 0.0 1.7 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein CAP PF00188.26 KXH62519.1 - 1.5e-11 45.3 0.0 2.2e-11 44.7 0.0 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family DPBB_1 PF03330.18 KXH62519.1 - 2.2e-05 24.7 0.0 4.6e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Lytic transglycolase Amidoligase_2 PF12224.8 KXH62520.1 - 1.9e-14 54.0 0.1 1.4e-07 31.4 0.0 5.1 4 2 0 4 4 4 3 Putative amidoligase enzyme SNF5 PF04855.12 KXH62521.1 - 2.1e-91 306.0 0.0 2.7e-91 305.6 0.0 1.1 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 GATA PF00320.27 KXH62521.1 - 0.011 15.3 4.5 0.03 13.9 4.5 1.8 1 0 0 1 1 1 0 GATA zinc finger Glyco_hydro_7 PF00840.20 KXH62522.1 - 1.4e-195 650.1 15.6 1.4e-195 650.1 15.6 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 7 CBM_1 PF00734.18 KXH62522.1 - 1.5e-12 47.3 14.3 1.5e-12 47.3 14.3 4.9 4 1 0 4 4 4 1 Fungal cellulose binding domain Fungal_trans PF04082.18 KXH62523.1 - 2.9e-11 42.9 0.0 4.8e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH62523.1 - 2.9e-06 27.3 13.3 4.6e-06 26.6 13.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXH62524.1 - 4.1e-15 55.5 0.0 1.3e-14 53.9 0.1 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH62524.1 - 3.4e-07 30.3 9.3 5.3e-07 29.7 9.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAT1 PF09770.9 KXH62524.1 - 1.2 7.3 24.1 1.8 6.7 24.1 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Sugar_tr PF00083.24 KXH62525.1 - 8e-100 334.8 23.8 9.1e-100 334.6 23.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH62525.1 - 4.1e-32 111.5 26.2 7.8e-26 90.8 3.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KXH62525.1 - 0.0026 16.1 2.4 0.0026 16.1 2.4 2.9 1 1 1 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family LRR19-TM PF15176.6 KXH62525.1 - 0.16 12.0 0.8 1.5 8.8 0.0 2.8 3 0 0 3 3 3 0 Leucine-rich repeat family 19 TM domain TPR_9 PF13371.6 KXH62526.1 - 0.02 15.0 0.1 0.069 13.3 0.1 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat PD40 PF07676.12 KXH62527.1 - 0.052 13.5 0.9 0.83 9.7 0.1 3.3 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat SIP1 PF04938.12 KXH62528.1 - 0.017 14.9 0.1 0.17 11.6 0.1 2.0 2 0 0 2 2 2 0 Survival motor neuron (SMN) interacting protein 1 (SIP1) vWA-TerF-like PF10138.9 KXH62528.1 - 0.043 13.9 0.0 0.12 12.5 0.0 1.7 2 0 0 2 2 2 0 vWA found in TerF C terminus FAD_binding_4 PF01565.23 KXH62529.1 - 1.6e-28 99.2 0.2 2.3e-28 98.7 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KXH62529.1 - 5.1e-11 42.5 0.2 1.4e-10 41.1 0.2 1.8 1 0 0 1 1 1 1 Berberine and berberine like DUF3050 PF11251.8 KXH62529.1 - 0.039 13.6 0.0 0.069 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3050) Glyco_hydro_2_C PF02836.17 KXH62530.1 - 0.022 13.9 0.0 0.033 13.3 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain DUF2154 PF09922.9 KXH62530.1 - 0.19 11.6 0.1 0.38 10.6 0.1 1.4 1 0 0 1 1 1 0 Cell wall-active antibiotics response 4TMS YvqF Alpha_L_fucos PF01120.17 KXH62534.1 - 4.2e-88 296.1 5.8 5.8e-88 295.7 5.8 1.1 1 0 0 1 1 1 1 Alpha-L-fucosidase GHL6 PF14871.6 KXH62534.1 - 0.11 12.6 0.0 0.28 11.3 0.0 1.7 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase 6 PKD_3 PF16820.5 KXH62534.1 - 8.3 6.2 6.8 5.4 6.9 0.1 3.4 4 0 0 4 4 4 0 PKD-like domain Lipase_3 PF01764.25 KXH62535.1 - 1.1e-05 25.3 0.0 2.4e-05 24.2 0.0 1.8 1 0 0 1 1 1 1 Lipase (class 3) EFG_IV PF03764.18 KXH62535.1 - 0.18 11.6 0.0 0.43 10.4 0.0 1.6 2 0 0 2 2 2 0 Elongation factor G, domain IV Cutinase PF01083.22 KXH62536.1 - 1.8e-46 158.3 2.4 2.4e-46 157.9 2.4 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 KXH62536.1 - 8.9e-05 22.1 0.2 0.00018 21.1 0.2 1.5 1 1 0 1 1 1 1 PE-PPE domain VirJ PF06057.11 KXH62536.1 - 0.13 12.1 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Glyco_hydro_43 PF04616.14 KXH62537.1 - 2.2e-43 148.6 3.4 3.1e-43 148.2 3.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 KXH62537.1 - 1.6e-22 80.3 0.0 2.2e-22 79.8 0.0 1.2 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain GST_N PF02798.20 KXH62538.1 - 3.4e-08 33.7 0.0 5.7e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KXH62538.1 - 1.5e-07 31.5 0.0 2.7e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KXH62538.1 - 1.5e-06 28.1 0.0 4.7e-06 26.5 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KXH62538.1 - 2.1e-05 24.8 0.0 4e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KXH62538.1 - 2.3e-05 24.5 0.0 4.2e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KXH62538.1 - 0.001 19.3 0.0 0.0019 18.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Fungal_trans PF04082.18 KXH62539.1 - 1.8e-09 37.0 0.6 7.9e-09 34.9 0.5 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain G10 PF01125.17 KXH62539.1 - 0.086 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 G10 protein DIOX_N PF14226.6 KXH62540.1 - 2.6e-15 57.2 0.0 4.4e-14 53.2 0.0 2.3 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KXH62540.1 - 2.2e-11 44.1 0.0 4e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.16 KXH62541.1 - 4.5e-34 117.9 22.0 6.1e-34 117.5 21.7 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Zn_clus PF00172.18 KXH62542.1 - 2.2e-09 37.3 8.1 5.4e-09 36.0 8.1 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KXH62542.1 - 4.3e-09 35.7 2.3 2.5e-08 33.2 2.3 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.18 KXH62542.1 - 0.0011 18.0 0.8 0.0043 16.1 0.0 2.1 1 1 1 2 2 2 1 Fungal specific transcription factor domain ADH_zinc_N PF00107.26 KXH62543.1 - 1.8e-21 76.4 0.3 3e-21 75.8 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXH62543.1 - 2.4e-21 75.7 2.2 6.6e-21 74.2 1.5 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 KXH62543.1 - 0.078 12.4 1.6 0.76 9.2 1.7 2.2 2 0 0 2 2 2 0 short chain dehydrogenase ADH_zinc_N_2 PF13602.6 KXH62543.1 - 0.1 13.7 0.0 0.17 13.0 0.0 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase TrkA_N PF02254.18 KXH62543.1 - 0.15 12.3 0.3 0.25 11.6 0.3 1.4 1 0 0 1 1 1 0 TrkA-N domain p450 PF00067.22 KXH62545.1 - 4.7e-49 167.4 0.1 6.1e-49 167.0 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 RTA1 PF04479.13 KXH62546.1 - 1.1e-73 247.3 4.1 1.1e-73 247.3 4.1 1.6 2 0 0 2 2 2 1 RTA1 like protein Stevor PF17410.2 KXH62546.1 - 0.17 11.4 0.0 0.25 10.9 0.0 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame DUF4173 PF13777.6 KXH62546.1 - 0.74 9.2 6.6 1.4 8.3 0.5 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4173) DUF3522 PF12036.8 KXH62546.1 - 0.8 10.0 7.3 4.1 7.6 1.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3522) 7TMR-DISM_7TM PF07695.11 KXH62546.1 - 1.3 8.9 17.1 0.059 13.3 4.1 2.5 2 1 0 2 2 2 0 7TM diverse intracellular signalling Cation_ATPase_C PF00689.21 KXH62546.1 - 2.4 7.8 8.7 1.4 8.6 1.1 2.7 2 2 0 2 2 2 0 Cation transporting ATPase, C-terminus Glyco_transf_28 PF03033.20 KXH62547.1 - 4.7e-26 91.5 0.0 1.1e-25 90.2 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain VPS13_C PF16909.5 KXH62547.1 - 6.9e-05 22.7 1.3 0.00029 20.7 0.4 2.1 2 0 0 2 2 2 1 Vacuolar-sorting-associated 13 protein C-terminal UDPGT PF00201.18 KXH62547.1 - 0.0034 16.2 0.0 0.0064 15.3 0.0 1.4 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase DUF3172 PF11371.8 KXH62548.1 - 3.2 7.5 5.2 28 4.4 0.2 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF3172) DUF4140 PF13600.6 KXH62548.1 - 5.5 7.5 24.8 11 6.6 0.6 6.8 1 1 7 8 8 8 0 N-terminal domain of unknown function (DUF4140) Lactamase_B PF00753.27 KXH62549.1 - 3.2e-16 59.9 0.0 4.5e-16 59.5 0.0 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KXH62549.1 - 3e-05 23.6 0.0 4.4e-05 23.1 0.0 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KXH62549.1 - 0.033 14.1 0.1 0.24 11.3 0.0 2.0 2 0 0 2 2 2 0 Beta-lactamase superfamily domain Tautomerase_3 PF14832.6 KXH62550.1 - 1.5e-42 145.0 0.0 1.8e-42 144.8 0.0 1.0 1 0 0 1 1 1 1 Putative oxalocrotonate tautomerase enzyme Tautomerase PF01361.21 KXH62550.1 - 0.032 14.1 0.0 0.069 13.1 0.0 1.5 1 1 0 1 1 1 0 Tautomerase enzyme DUF2538 PF10804.8 KXH62551.1 - 0.34 10.7 5.2 0.58 9.9 5.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2538) WSC PF01822.19 KXH62552.1 - 9.3e-08 32.2 9.1 1.7e-07 31.3 9.1 1.4 1 0 0 1 1 1 1 WSC domain VPS9 PF02204.18 KXH62553.1 - 6.2e-30 103.5 0.1 1.1e-29 102.7 0.1 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 KXH62553.1 - 8.8e-17 61.2 0.1 1.9e-16 60.1 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5601) CUE PF02845.16 KXH62553.1 - 1.3e-10 40.8 0.2 1e-09 37.9 0.0 2.2 2 0 0 2 2 2 1 CUE domain Cutinase PF01083.22 KXH62554.1 - 6e-47 159.9 2.3 7.2e-47 159.6 2.3 1.1 1 0 0 1 1 1 1 Cutinase VirJ PF06057.11 KXH62554.1 - 4.5e-05 23.4 0.0 6e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) PE-PPE PF08237.11 KXH62554.1 - 0.0014 18.2 0.0 0.002 17.7 0.0 1.2 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_2 PF02230.16 KXH62554.1 - 0.023 14.5 0.0 0.065 13.0 0.0 1.7 1 1 1 2 2 2 0 Phospholipase/Carboxylesterase DUF2974 PF11187.8 KXH62554.1 - 0.063 12.8 0.0 0.092 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Hydrolase_4 PF12146.8 KXH62554.1 - 0.14 11.4 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 PhoLip_ATPase_C PF16212.5 KXH62555.1 - 5.4e-66 222.9 19.3 1.2e-65 221.8 19.3 1.6 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KXH62555.1 - 1.2e-22 79.3 1.0 2.1e-21 75.4 0.0 2.5 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 KXH62555.1 - 1.3e-11 44.4 0.0 1.8e-10 40.8 0.0 2.5 3 0 0 3 3 3 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KXH62555.1 - 9e-10 39.2 0.1 3.3e-05 24.3 0.0 3.5 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KXH62555.1 - 1.7e-09 37.4 0.1 1.7e-09 37.4 0.1 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KXH62555.1 - 0.0084 15.9 0.0 0.083 12.6 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase p450 PF00067.22 KXH62556.1 - 3.7e-26 91.9 0.0 8.2e-23 80.9 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 MFS_1 PF07690.16 KXH62557.1 - 3.1e-40 138.2 58.8 1.8e-39 135.7 56.9 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily Saf_2TM PF18303.1 KXH62557.1 - 3.6 7.2 13.0 0.056 13.0 0.7 3.4 3 0 0 3 3 3 0 SAVED-fused 2TM effector domain F-box PF00646.33 KXH62559.1 - 4.3e-05 23.3 0.1 0.00013 21.7 0.1 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KXH62559.1 - 0.00021 21.1 0.1 0.00044 20.1 0.1 1.5 1 0 0 1 1 1 1 F-box-like p450 PF00067.22 KXH62560.1 - 1.1e-53 182.6 0.0 1.6e-53 182.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 2OG-FeII_Oxy_3 PF13640.6 KXH62563.1 - 0.012 16.4 0.0 0.031 15.2 0.0 1.6 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily Aldedh PF00171.22 KXH62564.1 - 3.7e-155 516.9 0.0 4.2e-155 516.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KXH62564.1 - 0.06 12.8 0.0 0.26 10.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) CVNH PF08881.10 KXH62565.1 - 1.7e-35 121.7 0.1 2.7e-35 121.1 0.1 1.3 1 0 0 1 1 1 1 CVNH domain LysM PF01476.20 KXH62565.1 - 4.4e-15 55.5 0.0 8.1e-15 54.6 0.0 1.5 1 0 0 1 1 1 1 LysM domain Rick_17kDa_Anti PF05433.15 KXH62565.1 - 1.3e-08 34.5 11.5 1.3e-08 34.5 11.5 2.2 2 0 0 2 2 2 1 Glycine zipper 2TM domain Gly-zipper_YMGG PF13441.6 KXH62565.1 - 0.00056 19.6 14.0 0.0021 17.8 14.0 2.0 1 0 0 1 1 1 1 YMGG-like Gly-zipper Gly-zipper_Omp PF13488.6 KXH62565.1 - 0.018 15.1 16.1 0.086 12.9 15.9 2.4 1 1 0 1 1 1 0 Glycine zipper DUF533 PF04391.12 KXH62565.1 - 0.062 12.9 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF533) Zip PF02535.22 KXH62565.1 - 0.24 10.6 1.7 0.31 10.2 1.7 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter SelP_N PF04592.14 KXH62565.1 - 1.6 8.1 11.1 3.3 7.0 11.1 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF4128 PF13554.6 KXH62567.1 - 0.033 14.3 0.0 0.039 14.0 0.0 1.1 1 0 0 1 1 1 0 Bacteriophage related domain of unknown function Glyco_hydro_3_C PF01915.22 KXH62568.1 - 1.1e-54 185.5 0.0 2.1e-54 184.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KXH62568.1 - 2e-50 172.0 0.0 3.1e-50 171.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KXH62568.1 - 2.8e-22 78.6 0.2 5.8e-22 77.6 0.2 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 KXH62568.1 - 3.8e-06 26.8 0.0 7.4e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 PA14 domain DUF4519 PF15012.6 KXH62569.1 - 0.4 10.9 4.1 6.8 6.9 0.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) MFS_1 PF07690.16 KXH62570.1 - 2.7e-25 89.1 23.8 4.2e-25 88.4 23.8 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily RPE65 PF03055.15 KXH62571.1 - 3.9e-105 352.7 0.0 4.6e-105 352.5 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein OPT PF03169.15 KXH62572.1 - 1.1e-117 394.2 41.6 1.3e-117 394.0 41.6 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF4131 PF13567.6 KXH62572.1 - 8.7 6.0 12.3 0.48 10.1 0.2 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) CVNH PF08881.10 KXH62573.1 - 6.2e-21 75.0 8.0 1.7e-11 44.7 0.3 3.5 2 1 2 4 4 4 3 CVNH domain His_Phos_1 PF00300.22 KXH62574.1 - 4.2e-15 56.0 4.6 9.8e-09 35.2 0.3 3.5 2 1 1 3 3 3 3 Histidine phosphatase superfamily (branch 1) ERCC4 PF02732.15 KXH62575.1 - 1.4e-29 103.3 0.0 2.7e-29 102.4 0.0 1.4 1 0 0 1 1 1 1 ERCC4 domain CPSF100_C PF13299.6 KXH62575.1 - 0.47 10.6 10.3 0.4 10.9 7.3 2.1 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Tim54 PF11711.8 KXH62575.1 - 6.8 5.4 14.5 6.4 5.5 11.4 2.0 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Hid1 PF12722.7 KXH62575.1 - 8.4 4.4 8.7 13 3.8 8.7 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF805 PF05656.14 KXH62576.1 - 5.6 7.4 14.0 1.7 9.1 6.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF805) Kinesin PF00225.23 KXH62577.1 - 1.5e-91 306.8 0.0 1.5e-91 306.8 0.0 3.0 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 KXH62577.1 - 3.7e-16 59.4 0.2 3.5e-13 49.7 0.0 3.5 2 1 0 3 3 3 2 Microtubule binding Spc7 PF08317.11 KXH62577.1 - 0.0013 17.7 17.3 0.0013 17.7 17.3 10.5 5 3 4 11 11 11 3 Spc7 kinetochore protein ABC_tran_Xtn PF12848.7 KXH62577.1 - 0.013 15.5 0.1 0.013 15.5 0.1 10.3 10 3 0 11 11 11 0 ABC transporter Fib_alpha PF08702.10 KXH62577.1 - 0.075 13.2 104.8 0.3 11.3 5.2 9.7 8 2 2 10 10 10 0 Fibrinogen alpha/beta chain family DNA_binding_1 PF01035.20 KXH62578.1 - 6.8e-24 83.8 1.6 2.9e-22 78.6 1.6 2.1 1 1 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Cmc1 PF08583.10 KXH62579.1 - 2.9 8.0 4.0 1.4 9.0 0.1 2.3 3 0 0 3 3 3 0 Cytochrome c oxidase biogenesis protein Cmc1 like Abhydrolase_3 PF07859.13 KXH62580.1 - 5.7e-40 137.4 0.0 7e-40 137.1 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KXH62580.1 - 0.00058 18.9 0.8 0.01 14.7 0.8 2.1 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S51 PF03575.17 KXH62580.1 - 0.12 12.0 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 Peptidase family S51 Epimerase PF01370.21 KXH62581.1 - 0.045 13.2 0.0 0.1 12.1 0.0 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family VIR_N PF15912.5 KXH62583.1 - 0.31 10.6 5.8 0.38 10.3 5.8 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal FAP PF07174.11 KXH62583.1 - 0.92 8.9 15.0 1.3 8.4 15.0 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Sulfate_transp PF00916.20 KXH62584.1 - 2.5e-112 375.4 18.8 3.1e-112 375.1 18.8 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KXH62584.1 - 3.9e-08 32.9 0.0 7e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 KXH62584.1 - 1.9e-05 25.0 4.6 1.9e-05 25.0 4.6 3.3 2 2 0 2 2 2 2 Molybdate transporter of MFS superfamily YdjM PF04307.14 KXH62584.1 - 0.002 17.5 0.0 0.019 14.3 0.0 2.6 2 2 0 2 2 2 1 LexA-binding, inner membrane-associated putative hydrolase DUF917 PF06032.12 KXH62585.1 - 6.8e-126 419.8 1.1 1.1e-125 419.1 1.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF917) Hydant_A_N PF05378.13 KXH62585.1 - 1.9e-29 102.6 1.7 1.2e-26 93.5 0.0 3.2 3 0 0 3 3 3 2 Hydantoinase/oxoprolinase N-terminal region Hydantoinase_A PF01968.18 KXH62585.1 - 2.3e-29 102.6 6.2 4.6e-26 91.8 0.2 3.6 3 1 1 4 4 4 2 Hydantoinase/oxoprolinase BcrAD_BadFG PF01869.20 KXH62585.1 - 1e-05 25.2 3.8 0.0033 17.0 0.0 3.7 2 1 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family MutL PF13941.6 KXH62585.1 - 0.00014 20.6 0.3 0.0054 15.4 0.0 2.4 2 0 0 2 2 2 1 MutL protein ROK PF00480.20 KXH62585.1 - 0.00028 20.4 0.2 0.0027 17.2 0.0 2.7 3 0 0 3 3 3 1 ROK family StbA PF06406.11 KXH62585.1 - 0.031 13.5 0.1 1.8 7.7 0.0 2.3 2 0 0 2 2 2 0 StbA protein FtsA PF14450.6 KXH62585.1 - 0.55 10.7 5.3 5.8 7.4 0.1 3.6 3 2 0 3 3 3 0 Cell division protein FtsA Glyco_hydro_92 PF07971.12 KXH62586.1 - 7.5e-141 470.2 0.0 9.7e-141 469.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 KXH62586.1 - 5.4e-60 203.2 0.7 8.4e-60 202.6 0.7 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain GFA PF04828.14 KXH62587.1 - 3.7e-16 59.2 0.5 3.7e-16 59.2 0.5 1.3 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Transpos_assoc PF13963.6 KXH62587.1 - 0.12 12.7 3.7 4.4 7.7 0.0 2.2 2 0 0 2 2 2 0 Transposase-associated domain zf-NADH-PPase PF09297.11 KXH62587.1 - 0.14 11.9 1.4 0.14 11.9 1.4 2.6 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Myticin-prepro PF10690.9 KXH62587.1 - 0.96 9.7 5.2 0.22 11.8 0.6 1.9 1 1 1 2 2 2 0 Myticin pre-proprotein from the mussel Antimicrobial25 PF16839.5 KXH62587.1 - 2.2 8.4 10.8 14 5.9 0.2 2.2 2 0 0 2 2 2 0 Nematode antimicrobial peptide Sulfatase PF00884.23 KXH62588.1 - 7.7e-66 222.6 0.2 1.1e-65 222.1 0.2 1.2 1 0 0 1 1 1 1 Sulfatase DUF4976 PF16347.5 KXH62588.1 - 0.014 15.6 0.0 0.04 14.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4976) Phosphodiest PF01663.22 KXH62588.1 - 0.017 14.8 0.7 0.85 9.1 0.1 2.2 2 0 0 2 2 2 0 Type I phosphodiesterase / nucleotide pyrophosphatase Glyco_hydro_18 PF00704.28 KXH62590.1 - 2.1e-75 254.4 1.7 2.4e-75 254.2 1.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 PapA_C PF16911.5 KXH62590.1 - 0.12 12.5 0.0 0.27 11.3 0.0 1.6 1 0 0 1 1 1 0 Phthiocerol/phthiodiolone dimycocerosyl transferase C-terminus Zn_clus PF00172.18 KXH62591.1 - 4.7e-06 26.6 8.5 9e-06 25.7 8.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4570 PF15134.6 KXH62591.1 - 0.13 12.3 0.2 0.27 11.3 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4570) Aldo_ket_red PF00248.21 KXH62592.1 - 1.7e-70 237.6 0.0 2e-70 237.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Shal-type PF11601.8 KXH62592.1 - 0.14 11.7 0.6 0.29 10.7 0.6 1.5 1 0 0 1 1 1 0 Shal-type voltage-gated potassium channels, N-terminal Epimerase PF01370.21 KXH62593.1 - 6.1e-22 78.3 0.0 7.7e-22 77.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXH62593.1 - 1.7e-15 56.8 0.0 2.4e-15 56.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KXH62593.1 - 2.6e-10 40.2 0.0 4.2e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KXH62593.1 - 3.5e-07 29.6 0.0 5.2e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 KXH62593.1 - 1.3e-06 27.7 0.0 0.045 12.9 0.0 2.5 2 1 0 2 2 2 2 Male sterility protein adh_short PF00106.25 KXH62593.1 - 0.00052 19.5 0.0 0.015 14.8 0.0 2.6 2 1 0 2 2 2 1 short chain dehydrogenase NAD_binding_10 PF13460.6 KXH62593.1 - 0.00098 19.1 0.0 0.0014 18.6 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KXH62593.1 - 0.017 14.3 0.0 0.34 10.0 0.0 2.1 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Ldh_1_N PF00056.23 KXH62593.1 - 0.018 15.1 0.0 0.034 14.2 0.0 1.6 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain NmrA PF05368.13 KXH62593.1 - 0.043 13.4 0.2 1.7 8.1 0.0 2.2 2 0 0 2 2 2 0 NmrA-like family FMN_dh PF01070.18 KXH62594.1 - 2.9e-116 388.3 0.0 3.5e-116 388.0 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 KXH62594.1 - 1.8e-19 69.7 0.0 4.4e-19 68.4 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 KXH62594.1 - 0.00033 19.9 0.0 0.0007 18.8 0.0 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase ThiG PF05690.14 KXH62594.1 - 0.0022 17.4 0.1 0.099 11.9 0.0 2.3 1 1 1 2 2 2 1 Thiazole biosynthesis protein ThiG IMPDH PF00478.25 KXH62594.1 - 0.003 16.6 0.2 0.0085 15.1 0.2 1.7 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 KXH62594.1 - 0.037 13.4 0.0 0.061 12.7 0.0 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase DHDPS PF00701.22 KXH62595.1 - 2.7e-40 137.9 0.0 3.4e-40 137.6 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family GGDEF_2 PF17853.1 KXH62595.1 - 0.089 13.1 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 GGDEF-like domain BNR_2 PF13088.6 KXH62596.1 - 2.8e-65 220.4 0.7 3.4e-65 220.1 0.7 1.0 1 0 0 1 1 1 1 BNR repeat-like domain BNR PF02012.20 KXH62596.1 - 0.0005 19.7 13.0 0.5 10.6 0.2 4.6 5 0 0 5 5 5 2 BNR/Asp-box repeat BNR_4 PF15892.5 KXH62596.1 - 0.0038 16.6 0.0 1.7 8.0 0.0 2.3 2 0 0 2 2 2 2 BNR repeat-containing family member Glyco_hydro_43 PF04616.14 KXH62596.1 - 0.013 14.9 0.1 0.03 13.6 0.1 1.6 1 1 0 1 1 1 0 Glycosyl hydrolases family 43 PSII_BNR PF14870.6 KXH62596.1 - 0.023 13.9 0.9 0.41 9.9 0.1 2.7 3 0 0 3 3 3 0 Photosynthesis system II assembly factor YCF48 Sortilin-Vps10 PF15902.5 KXH62596.1 - 0.046 12.5 0.6 0.51 9.1 0.1 2.5 2 1 0 2 2 2 0 Sortilin, neurotensin receptor 3, Sugar_tr PF00083.24 KXH62597.1 - 3.8e-98 329.3 16.5 4.3e-98 329.1 16.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH62597.1 - 2.5e-23 82.6 15.0 2.5e-23 82.6 15.0 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_5 PF05631.14 KXH62597.1 - 0.00043 19.3 2.2 0.0024 16.9 0.1 2.6 3 1 0 3 3 3 1 Sugar-tranasporters, 12 TM p450 PF00067.22 KXH62598.1 - 7.1e-69 232.7 0.0 8.8e-69 232.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 End_N_terminal PF12218.8 KXH62598.1 - 0.064 13.0 0.0 11 5.9 0.0 2.6 3 0 0 3 3 3 0 N terminal extension of bacteriophage endosialidase Fungal_trans_2 PF11951.8 KXH62599.1 - 1.9e-47 161.9 1.0 2.4e-47 161.6 1.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Aminotran_3 PF00202.21 KXH62600.1 - 8e-88 294.8 0.0 1e-87 294.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III MID_MedPIWI PF18296.1 KXH62601.1 - 0.0052 16.6 1.3 0.0071 16.2 1.3 1.2 1 0 0 1 1 1 1 MID domain of medPIWI AJAP1_PANP_C PF15298.6 KXH62601.1 - 0.14 12.4 11.3 0.19 12.0 11.3 1.2 1 0 0 1 1 1 0 AJAP1/PANP C-terminus PH_12 PF16457.5 KXH62601.1 - 0.25 11.9 3.9 0.56 10.7 3.9 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain Pec_lyase_C PF00544.19 KXH62602.1 - 2.2e-42 145.0 5.6 3.4e-42 144.4 5.6 1.2 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 KXH62602.1 - 3.6e-06 26.9 7.2 4.4e-05 23.4 7.2 2.2 1 1 0 1 1 1 1 Right handed beta helix region PSI_PsaH PF03244.14 KXH62602.1 - 0.02 14.4 0.1 0.046 13.2 0.1 1.6 1 0 0 1 1 1 0 Photosystem I reaction centre subunit VI MIP PF00230.20 KXH62603.1 - 6e-48 163.5 13.0 7.7e-48 163.2 13.0 1.1 1 0 0 1 1 1 1 Major intrinsic protein HPP PF04982.13 KXH62604.1 - 1.1e-31 109.5 4.5 1.1e-31 109.5 4.5 1.9 2 1 0 2 2 2 1 HPP family adh_short PF00106.25 KXH62605.1 - 2.5e-26 92.4 0.4 2.2e-22 79.5 0.4 2.3 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXH62605.1 - 2.4e-14 53.5 0.1 1.4e-12 47.7 0.2 2.1 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH62605.1 - 2.2e-05 24.5 0.1 5.1e-05 23.3 0.0 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KXH62605.1 - 0.0039 16.7 0.2 0.011 15.2 0.2 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KXH62605.1 - 0.017 14.2 0.0 0.073 12.2 0.0 1.9 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KXH62605.1 - 0.051 13.0 0.1 0.098 12.0 0.1 1.5 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase Methyltransf_PK PF05891.12 KXH62605.1 - 0.095 12.2 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase DUF3176 PF11374.8 KXH62606.1 - 0.019 15.2 1.3 0.042 14.0 1.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3176) p450 PF00067.22 KXH62607.1 - 9.5e-42 143.3 0.0 1.4e-41 142.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 TFR_dimer PF04253.15 KXH62608.1 - 1.7e-23 83.0 0.0 3.6e-23 82.0 0.0 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 KXH62608.1 - 2.7e-20 72.9 0.0 4.9e-20 72.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KXH62608.1 - 1.2e-11 44.5 0.3 1.4e-10 41.1 0.3 2.5 1 1 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 KXH62608.1 - 0.025 14.3 0.0 0.045 13.4 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 DUF4165 PF13752.6 KXH62608.1 - 0.15 12.0 0.0 1.2 9.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4165) AAA PF00004.29 KXH62609.1 - 4.5e-18 65.9 0.0 8.3e-18 65.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KXH62609.1 - 0.00032 21.1 0.0 0.001 19.5 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 KXH62609.1 - 0.0025 17.6 0.0 0.0052 16.5 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 KXH62609.1 - 0.0041 17.7 0.4 0.29 11.7 0.0 3.6 3 1 0 3 3 3 1 AAA domain AAA_22 PF13401.6 KXH62609.1 - 0.0091 16.3 0.1 0.039 14.2 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KXH62609.1 - 0.042 13.9 0.1 0.13 12.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KXH62609.1 - 0.048 13.8 0.0 0.39 10.8 0.0 2.3 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_17 PF13207.6 KXH62609.1 - 0.086 13.3 0.0 0.26 11.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KXH62609.1 - 0.11 12.7 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain CBM_20 PF00686.19 KXH62610.1 - 9e-34 115.3 0.8 1.7e-33 114.3 0.8 1.5 1 0 0 1 1 1 1 Starch binding domain LPMO_10 PF03067.15 KXH62610.1 - 3.6e-11 44.1 3.5 3.6e-11 44.1 3.5 1.9 2 0 0 2 2 2 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Glyco_hydro_61 PF03443.14 KXH62610.1 - 0.00016 21.7 0.2 0.0013 18.7 0.1 2.2 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 DUF805 PF05656.14 KXH62611.1 - 2.2 8.7 15.3 1.6 9.2 12.8 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF805) Abhydrolase_6 PF12697.7 KXH62612.1 - 7.3e-06 26.7 0.0 9.5e-05 23.1 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXH62612.1 - 0.11 11.8 0.1 14 4.9 0.0 2.3 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Peptidase_S8 PF00082.22 KXH62613.1 - 1.3e-52 178.9 0.0 2.4e-52 178.1 0.0 1.4 1 1 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 KXH62613.1 - 5e-08 33.6 0.0 1.1e-07 32.5 0.0 1.6 1 0 0 1 1 1 1 Fn3-like domain BNR PF02012.20 KXH62614.1 - 0.00055 19.5 2.3 0.91 9.8 0.0 3.7 3 0 0 3 3 3 2 BNR/Asp-box repeat BNR_2 PF13088.6 KXH62614.1 - 0.005 16.2 0.0 0.014 14.7 0.0 1.7 1 1 0 1 1 1 1 BNR repeat-like domain Sortilin-Vps10 PF15902.5 KXH62614.1 - 0.08 11.7 0.2 11 4.7 0.1 2.8 3 1 1 4 4 4 0 Sortilin, neurotensin receptor 3, Glyco_hydro_35 PF01301.19 KXH62615.1 - 5.3e-90 302.3 1.1 7.8e-90 301.7 1.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.9 KXH62615.1 - 1.6e-60 204.0 5.0 3.3e-60 203.0 5.0 1.5 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.6 KXH62615.1 - 1.7e-57 192.9 4.4 1.3e-30 106.3 0.0 3.0 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.6 KXH62615.1 - 8.4e-22 76.5 1.1 3.6e-21 74.5 0.1 2.5 2 0 0 2 2 2 1 Beta-galactosidase, domain 3 Fve PF09259.11 KXH62615.1 - 0.026 14.7 0.3 0.14 12.3 0.0 2.3 2 0 0 2 2 2 0 Fungal immunomodulatory protein Fve Glyco_hydro_28 PF00295.17 KXH62616.1 - 2.4e-115 385.1 21.9 2.9e-115 384.8 21.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 MFS_1 PF07690.16 KXH62617.1 - 2.3e-15 56.4 27.5 6.6e-13 48.3 22.8 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KXH62617.1 - 9.7 4.6 15.6 0.087 11.4 6.4 2.1 2 1 1 3 3 3 0 MFS/sugar transport protein HSP70 PF00012.20 KXH62618.1 - 4.2e-16 58.3 0.2 7.1e-14 50.9 0.3 2.2 2 0 0 2 2 2 2 Hsp70 protein NTP_transf_7 PF07984.12 KXH62618.1 - 0.066 12.4 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 Nucleotidyltransferase TPR_MLP1_2 PF07926.12 KXH62619.1 - 0.00079 19.5 4.0 0.0012 18.9 4.0 1.3 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein Jnk-SapK_ap_N PF09744.9 KXH62619.1 - 0.0015 18.8 3.2 0.0022 18.2 3.2 1.2 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 Tropomyosin PF00261.20 KXH62619.1 - 0.0048 16.3 5.4 0.0074 15.7 5.4 1.3 1 0 0 1 1 1 1 Tropomyosin DUF4407 PF14362.6 KXH62619.1 - 0.016 14.6 2.0 0.022 14.1 2.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SIKE PF05769.11 KXH62619.1 - 0.025 14.5 2.4 0.038 13.9 2.4 1.2 1 0 0 1 1 1 0 SIKE family Herpes_BLRF2 PF05812.12 KXH62619.1 - 0.029 14.5 0.7 0.068 13.3 0.1 1.9 1 1 1 2 2 2 0 Herpesvirus BLRF2 protein KASH_CCD PF14662.6 KXH62619.1 - 0.041 13.7 1.9 0.064 13.1 1.9 1.3 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH HAUS-augmin3 PF14932.6 KXH62619.1 - 0.048 13.2 0.9 0.074 12.6 0.9 1.3 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 GIT_CC PF16559.5 KXH62619.1 - 0.06 13.2 0.2 0.18 11.7 0.2 1.7 1 1 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor HAUS6_N PF14661.6 KXH62619.1 - 0.071 12.7 2.2 0.053 13.1 0.9 1.4 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus GAS PF13851.6 KXH62619.1 - 0.086 12.2 4.1 0.45 9.8 0.6 2.0 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Cep57_CLD_2 PF14197.6 KXH62619.1 - 0.1 12.7 2.2 9.2 6.4 0.1 2.4 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 DivIC PF04977.15 KXH62619.1 - 0.11 12.3 3.2 0.18 11.6 0.1 2.1 2 0 0 2 2 2 0 Septum formation initiator Phage_GP20 PF06810.11 KXH62619.1 - 0.11 12.3 1.4 0.25 11.1 0.3 1.9 1 1 1 2 2 2 0 Phage minor structural protein GP20 DUF724 PF05266.14 KXH62619.1 - 0.13 12.1 2.1 0.24 11.2 2.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF724) CENP-F_leu_zip PF10473.9 KXH62619.1 - 0.14 12.1 4.1 0.3 11.1 4.0 1.5 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Baculo_PEP_C PF04513.12 KXH62619.1 - 0.17 11.9 0.8 0.27 11.3 0.8 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Lebercilin PF15619.6 KXH62619.1 - 0.2 11.3 6.4 0.35 10.5 0.4 2.0 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Spc7 PF08317.11 KXH62619.1 - 0.21 10.4 3.8 0.34 9.7 3.8 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein XhlA PF10779.9 KXH62619.1 - 0.39 10.9 3.6 8.9 6.6 0.5 2.3 1 1 1 2 2 2 0 Haemolysin XhlA Atg14 PF10186.9 KXH62619.1 - 0.4 9.7 3.2 0.59 9.2 3.2 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 ZapB PF06005.12 KXH62619.1 - 0.45 11.0 5.7 0.17 12.3 0.6 2.2 1 1 1 2 2 2 0 Cell division protein ZapB Fez1 PF06818.15 KXH62619.1 - 0.73 10.3 4.0 1.1 9.6 4.0 1.3 1 0 0 1 1 1 0 Fez1 Cnn_1N PF07989.11 KXH62619.1 - 0.94 9.7 4.6 4.7 7.4 4.6 2.1 1 1 0 1 1 1 0 Centrosomin N-terminal motif 1 TMF_DNA_bd PF12329.8 KXH62619.1 - 0.95 9.5 5.4 3.5 7.7 0.3 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding TSC22 PF01166.18 KXH62619.1 - 1.3 9.4 5.0 3.4 8.0 0.4 2.6 1 1 0 2 2 2 0 TSC-22/dip/bun family DUF4200 PF13863.6 KXH62619.1 - 1.4 9.4 6.0 49 4.4 6.0 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) JIP_LZII PF16471.5 KXH62619.1 - 2 8.6 6.1 3.6 7.8 0.1 2.6 2 1 1 3 3 3 0 JNK-interacting protein leucine zipper II APG6_N PF17675.1 KXH62619.1 - 2.8 8.5 6.4 5.4 7.5 6.4 1.5 1 1 0 1 1 1 0 Apg6 coiled-coil region IBR PF01485.21 KXH62620.1 - 1e-10 41.7 1.5 1e-10 41.7 1.5 2.5 2 1 0 2 2 2 1 IBR domain, a half RING-finger domain zinc_ribbon_12 PF11331.8 KXH62620.1 - 0.03 14.1 2.6 0.11 12.3 1.0 2.3 2 0 0 2 2 2 0 Probable zinc-ribbon domain ABC_membrane_2 PF06472.15 KXH62621.1 - 4.2e-103 344.4 0.4 4.2e-103 344.4 0.4 1.4 2 0 0 2 2 2 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 KXH62621.1 - 1.5e-17 64.4 0.0 3.3e-17 63.3 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KXH62621.1 - 0.0002 21.3 0.0 0.00057 19.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KXH62621.1 - 0.0095 16.3 0.5 0.39 11.1 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 KXH62621.1 - 0.022 15.3 0.0 0.15 12.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 KXH62621.1 - 0.079 12.4 0.0 0.25 10.8 0.0 1.8 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KXH62621.1 - 0.084 12.6 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RuvB_N PF05496.12 KXH62621.1 - 0.12 12.1 0.0 0.33 10.7 0.0 1.7 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Rad17 PF03215.15 KXH62621.1 - 0.15 12.0 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain zf-CSL PF05207.13 KXH62622.1 - 3.6e-23 81.0 0.7 4.9e-23 80.6 0.7 1.2 1 0 0 1 1 1 1 CSL zinc finger Zn-ribbon_8 PF09723.10 KXH62622.1 - 2.2e-05 24.5 0.6 3.4e-05 23.9 0.6 1.3 1 0 0 1 1 1 1 Zinc ribbon domain Terminase_GpA PF05876.12 KXH62622.1 - 0.033 12.7 0.1 0.039 12.5 0.1 1.1 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) Prok-RING_1 PF14446.6 KXH62622.1 - 0.32 11.0 3.5 0.68 9.9 3.5 1.6 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 DUF4244 PF14029.6 KXH62630.1 - 0.013 14.9 0.4 0.037 13.5 0.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4244) PGG PF13962.6 KXH62630.1 - 0.086 12.7 0.1 0.086 12.7 0.1 2.2 3 0 0 3 3 3 0 Domain of unknown function CPG4 PF15481.6 KXH62630.1 - 0.1 13.2 0.2 0.24 12.1 0.2 1.5 1 0 0 1 1 1 0 Chondroitin proteoglycan 4 E1-E2_ATPase PF00122.20 KXH62630.1 - 0.17 11.4 2.4 0.18 11.3 0.1 1.9 2 0 0 2 2 2 0 E1-E2 ATPase DUF3176 PF11374.8 KXH62630.1 - 1 9.6 7.0 0.1 12.8 2.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3176) adh_short PF00106.25 KXH62631.1 - 2.3e-45 154.5 2.7 3e-45 154.1 2.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXH62631.1 - 9e-41 140.0 1.4 1.1e-40 139.6 1.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH62631.1 - 2.5e-09 37.3 0.4 4.7e-09 36.4 0.2 1.6 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 KXH62631.1 - 0.001 18.3 0.1 0.0015 17.8 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3HCDH_N PF02737.18 KXH62631.1 - 0.0018 18.2 0.4 0.0032 17.4 0.4 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.21 KXH62631.1 - 0.032 13.7 0.1 0.037 13.5 0.1 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Mito_carr PF00153.27 KXH62633.1 - 9.1e-39 131.3 6.2 1.6e-16 59.9 0.2 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KXH62633.1 - 0.003 16.8 0.2 0.007 15.6 0.2 1.7 1 0 0 1 1 1 1 Gammaproteobacterial serine protease Metallophos PF00149.28 KXH62636.1 - 1.7e-10 41.7 0.8 3.6e-10 40.7 0.8 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase 5_nucleotid_C PF02872.18 KXH62636.1 - 0.082 13.1 0.0 0.21 11.8 0.0 1.6 1 1 0 1 1 1 0 5'-nucleotidase, C-terminal domain zf-C2H2 PF00096.26 KXH62644.1 - 1.2e-09 38.1 11.5 2.6e-05 24.4 4.5 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KXH62644.1 - 4.7e-09 36.3 13.8 5.7e-05 23.4 0.5 3.6 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KXH62644.1 - 1.3e-06 28.8 11.1 0.0015 19.2 3.2 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 KXH62644.1 - 7.7e-06 26.1 1.3 2.1e-05 24.7 1.3 1.8 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KXH62644.1 - 0.00014 21.8 2.4 0.00014 21.8 2.4 2.6 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KXH62644.1 - 0.00088 19.5 1.8 0.00088 19.5 1.8 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KXH62644.1 - 0.039 14.3 0.9 0.039 14.3 0.9 2.1 2 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2HC_2 PF13913.6 KXH62644.1 - 0.26 11.2 5.3 3.4 7.7 0.4 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_11 PF16622.5 KXH62644.1 - 0.78 9.6 8.3 8.3 6.3 1.2 2.8 2 0 0 2 2 2 0 zinc-finger C2H2-type OTT_1508_deam PF14441.6 KXH62680.1 - 1.7e-19 69.6 1.2 4.1e-19 68.3 1.2 1.7 1 0 0 1 1 1 1 OTT_1508-like deaminase LMBR1 PF04791.16 KXH62680.1 - 0.0095 14.9 0.1 0.0095 14.9 0.1 1.2 1 0 0 1 1 1 1 LMBR1-like membrane protein DUF327 PF03885.13 KXH62680.1 - 0.3 11.0 4.5 4.3 7.3 0.4 2.8 3 1 0 3 3 3 0 Protein of unknown function (DUF327) Orbi_VP1 PF05788.12 KXH62681.1 - 0.02 12.5 0.1 0.022 12.4 0.1 1.0 1 0 0 1 1 1 0 Orbivirus RNA-dependent RNA polymerase (VP1) DUF4804 PF16062.5 KXH62681.1 - 0.063 12.1 0.0 0.065 12.1 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4804) zf-C2H2_jaz PF12171.8 KXH62682.1 - 6.9e-34 115.4 16.8 4.5e-05 23.6 0.1 6.7 6 0 0 6 6 6 6 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KXH62682.1 - 2.6e-24 84.8 17.1 0.0015 18.9 0.2 6.6 6 0 0 6 6 6 6 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 KXH62682.1 - 4.9e-24 83.4 21.6 0.0026 18.1 0.3 7.5 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXH62682.1 - 3.5e-19 67.9 18.3 0.047 14.5 0.2 7.9 8 0 0 8 8 7 6 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KXH62682.1 - 2.4e-16 59.3 14.0 0.0095 15.9 0.1 6.8 6 0 0 6 6 6 5 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KXH62682.1 - 2.3e-15 56.2 20.0 0.0089 16.4 0.1 7.6 8 0 0 8 8 8 4 Zinc-finger double domain zf-C2HC_2 PF13913.6 KXH62682.1 - 4.8e-14 51.8 14.5 0.0063 16.4 0.2 6.5 6 0 0 6 6 6 5 zinc-finger of a C2HC-type zf-C2H2_2 PF12756.7 KXH62682.1 - 1.1e-11 44.9 19.5 0.021 15.1 0.3 6.9 2 1 5 7 7 7 5 C2H2 type zinc-finger (2 copies) zf_C2H2_ZHX PF18387.1 KXH62682.1 - 8.5e-07 28.5 16.5 2.6 7.7 0.1 6.3 5 1 1 6 6 6 3 Zinc-fingers and homeoboxes C2H2 finger domain LIM PF00412.22 KXH62682.1 - 2.8e-06 27.4 11.1 0.37 11.1 1.1 4.4 1 1 4 5 5 5 5 LIM domain zf_UBZ PF18439.1 KXH62682.1 - 9.7e-06 25.1 17.3 3.5 7.3 0.1 6.4 6 0 0 6 6 6 2 Ubiquitin-Binding Zinc Finger DUF2256 PF10013.9 KXH62682.1 - 2.6e-05 24.2 5.4 24 5.1 0.1 6.0 6 0 0 6 6 6 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2H2_11 PF16622.5 KXH62682.1 - 0.00055 19.6 18.2 0.31 10.9 0.6 6.8 5 1 2 7 7 7 1 zinc-finger C2H2-type C1_4 PF07975.12 KXH62682.1 - 0.001 19.2 20.1 0.92 9.8 0.9 4.9 1 1 4 5 5 5 3 TFIIH C1-like domain zf-AN1 PF01428.16 KXH62682.1 - 0.022 14.9 15.5 23 5.3 0.1 6.3 6 0 0 6 6 6 0 AN1-like Zinc finger Actin_micro PF17003.5 KXH62682.1 - 0.05 12.8 6.3 0.68 9.1 0.2 4.0 1 1 1 2 2 2 0 Putative actin-like family zinc_ribbon_15 PF17032.5 KXH62682.1 - 0.08 13.7 16.9 1.9 9.3 2.0 3.8 1 1 2 3 3 3 0 zinc-ribbon family zf-C2H2_8 PF15909.5 KXH62682.1 - 0.25 11.7 10.0 0.27 11.6 0.8 3.6 2 1 3 5 5 5 0 C2H2-type zinc ribbon HNH_5 PF14279.6 KXH62682.1 - 0.56 10.1 19.4 6.3 6.8 1.6 6.1 5 1 0 5 5 5 0 HNH endonuclease Extensin_1 PF02095.15 KXH62682.1 - 0.72 10.2 12.6 3 8.3 0.3 3.6 4 0 0 4 4 3 0 Extensin-like protein repeat DUF2225 PF09986.9 KXH62682.1 - 5 6.8 9.8 3.1 7.5 0.6 4.1 1 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) Cript PF10235.9 KXH62682.1 - 7.2 7.3 12.6 68 4.1 0.4 4.8 2 1 3 5 5 4 0 Microtubule-associated protein CRIPT DNA_pol_A_exo1 PF01612.20 KXH62683.1 - 1.6e-13 50.8 0.0 2.2e-13 50.3 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease FtsJ PF01728.19 KXH62684.1 - 9.4e-14 51.9 0.0 1.3e-13 51.5 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltr_RsmB-F PF01189.17 KXH62684.1 - 0.0075 15.9 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F DUF2263 PF10021.9 KXH62700.1 - 1.4e-10 41.7 0.0 2.5e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) BORCS6 PF10157.9 KXH62700.1 - 1.4 9.2 4.0 2.1 8.6 4.0 1.2 1 0 0 1 1 1 0 BLOC-1-related complex sub-unit 6 CCDC24 PF15669.5 KXH62700.1 - 1.7 8.4 3.3 3.2 7.6 3.3 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family RSRP PF17069.5 KXH62700.1 - 2.7 7.5 17.4 4.5 6.8 17.4 1.3 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 SR-25 PF10500.9 KXH62700.1 - 4.1 6.9 20.2 6.2 6.4 20.2 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RAP1 PF07218.11 KXH62700.1 - 9.5 4.4 9.2 13 4.0 9.2 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) tRNA-synt_2 PF00152.20 KXH62701.1 - 9.5e-79 264.7 0.0 1.1e-78 264.5 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.25 KXH62701.1 - 0.058 13.4 0.0 0.14 12.2 0.0 1.6 2 0 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2d PF01409.20 KXH62701.1 - 0.082 12.4 0.1 2 7.9 0.0 2.1 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) DUF2434 PF10361.9 KXH62719.1 - 1.1e-129 431.6 6.7 1.4e-129 431.3 6.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2434) CitMHS PF03600.16 KXH62719.1 - 0.045 12.9 0.0 0.067 12.4 0.0 1.3 1 1 0 1 1 1 0 Citrate transporter ABC2_membrane_2 PF12679.7 KXH62719.1 - 0.046 13.0 0.0 0.096 11.9 0.0 1.5 1 0 0 1 1 1 0 ABC-2 family transporter protein COG5 PF10392.9 KXH62720.1 - 2.1e-38 131.5 4.9 2.8e-38 131.1 0.6 2.5 3 0 0 3 3 3 1 Golgi transport complex subunit 5 SRX PF09201.10 KXH62720.1 - 0.029 14.2 0.0 0.056 13.3 0.0 1.4 1 0 0 1 1 1 0 SRX, signal recognition particle receptor alpha subunit ATG16 PF08614.11 KXH62720.1 - 0.03 14.5 1.0 0.067 13.4 1.0 1.6 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DHFR_2 PF06442.11 KXH62720.1 - 0.049 13.5 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 R67 dihydrofolate reductase AAA_13 PF13166.6 KXH62720.1 - 0.056 12.1 0.8 1.2 7.6 0.1 2.0 2 0 0 2 2 2 0 AAA domain Lebercilin PF15619.6 KXH62720.1 - 0.066 12.9 2.3 0.14 11.8 2.3 1.5 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease GrpE PF01025.19 KXH62720.1 - 0.1 12.3 1.6 0.2 11.3 1.6 1.4 1 0 0 1 1 1 0 GrpE p450 PF00067.22 KXH62722.1 - 3.7e-54 184.2 0.0 5e-54 183.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 RTA1 PF04479.13 KXH62723.1 - 5e-61 205.9 13.8 6.8e-61 205.5 13.8 1.2 1 0 0 1 1 1 1 RTA1 like protein Bac_export_2 PF01312.19 KXH62723.1 - 1.1 8.3 3.0 6.7 5.8 3.0 2.0 1 1 0 1 1 1 0 FlhB HrpN YscU SpaS Family adh_short_C2 PF13561.6 KXH62724.1 - 4.3e-46 157.4 0.0 5.6e-46 157.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXH62724.1 - 6.9e-37 126.8 0.0 9.6e-37 126.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXH62724.1 - 5.6e-13 49.2 0.0 8e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 KR domain Rieske PF00355.26 KXH62724.1 - 6.5e-08 32.4 0.0 1.3e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Epimerase PF01370.21 KXH62724.1 - 1.1e-06 28.3 0.0 3.1e-06 26.8 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KXH62724.1 - 0.00053 19.2 0.0 0.00098 18.3 0.0 1.3 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KXH62724.1 - 0.0031 17.0 0.0 0.0046 16.4 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase TrkA_N PF02254.18 KXH62724.1 - 0.036 14.3 0.0 0.091 13.0 0.0 1.7 2 0 0 2 2 2 0 TrkA-N domain Pyr_redox PF00070.27 KXH62724.1 - 0.053 14.1 0.0 0.12 13.0 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase RmlD_sub_bind PF04321.17 KXH62724.1 - 0.058 12.5 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain NAD_binding_2 PF03446.15 KXH62724.1 - 0.071 13.3 0.0 1.2 9.3 0.0 2.2 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 KXH62724.1 - 0.079 12.8 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KXH62724.1 - 0.13 11.3 0.0 0.46 9.4 0.0 1.9 1 1 1 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Ank_2 PF12796.7 KXH62725.1 - 9.8e-31 106.2 1.3 5e-08 33.4 0.0 4.4 2 1 4 6 6 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXH62725.1 - 1.6e-23 82.8 0.1 0.00039 20.9 0.0 6.2 4 2 1 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXH62725.1 - 8e-18 62.7 0.0 0.061 13.9 0.0 8.0 8 0 0 8 8 8 3 Ankyrin repeat Ank PF00023.30 KXH62725.1 - 5e-14 52.0 0.1 0.22 12.1 0.0 7.8 8 0 0 8 8 8 3 Ankyrin repeat Ank_5 PF13857.6 KXH62725.1 - 9.1e-13 48.2 1.1 0.18 12.2 0.1 5.9 4 3 2 6 6 6 5 Ankyrin repeats (many copies) NACHT PF05729.12 KXH62725.1 - 2.9e-09 37.0 0.0 8.3e-09 35.6 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KXH62725.1 - 3.8e-06 27.4 0.1 2.9e-05 24.5 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain KAP_NTPase PF07693.14 KXH62725.1 - 2.3e-05 23.8 1.2 0.035 13.3 0.4 2.9 2 1 1 3 3 3 2 KAP family P-loop domain AAA_22 PF13401.6 KXH62725.1 - 7.1e-05 23.1 0.1 0.00041 20.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KXH62725.1 - 0.042 14.3 0.1 0.36 11.2 0.0 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 KXH62725.1 - 0.097 11.8 0.0 0.2 10.8 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain BUD22 PF09073.10 KXH62726.1 - 0.081 12.3 24.4 0.0097 15.3 20.0 1.6 2 0 0 2 2 2 0 BUD22 Phage_holin_2_3 PF16080.5 KXH62726.1 - 0.13 12.0 0.7 0.24 11.2 0.7 1.4 1 0 0 1 1 1 0 Bacteriophage holin family HP1 TFIIF_alpha PF05793.12 KXH62726.1 - 0.14 10.7 14.1 0.25 9.9 14.1 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) RIFIN PF02009.16 KXH62726.1 - 2 8.2 0.0 2 8.2 0.0 2.6 3 0 0 3 3 3 0 Rifin cobW PF02492.19 KXH62727.1 - 3.3e-49 166.9 5.1 1.7e-36 125.5 0.3 2.2 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 KXH62727.1 - 4e-17 61.9 0.0 1.1e-13 50.9 0.0 2.6 2 0 0 2 2 2 2 Cobalamin synthesis protein cobW C-terminal domain MeaB PF03308.16 KXH62727.1 - 3.2e-06 26.3 0.8 0.00026 20.0 0.0 2.3 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB MobB PF03205.14 KXH62727.1 - 0.0047 16.8 0.0 0.0089 15.9 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.6 KXH62727.1 - 0.0078 16.6 2.1 0.014 15.8 0.5 2.3 2 1 0 2 2 2 1 AAA ATPase domain Viral_helicase1 PF01443.18 KXH62727.1 - 0.01 15.6 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RsgA_GTPase PF03193.16 KXH62727.1 - 0.01 15.7 0.6 1.6 8.6 0.1 2.4 2 0 0 2 2 2 0 RsgA GTPase TsaE PF02367.17 KXH62727.1 - 0.024 14.6 0.0 0.056 13.5 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 KXH62727.1 - 0.037 14.2 0.2 0.26 11.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain Nop14 PF04147.12 KXH62727.1 - 0.046 12.0 11.6 0.073 11.3 11.6 1.2 1 0 0 1 1 1 0 Nop14-like family Drc1-Sld2 PF11719.8 KXH62727.1 - 0.23 11.0 3.9 0.34 10.4 3.9 1.2 1 0 0 1 1 1 0 DNA replication and checkpoint protein TFIIA PF03153.13 KXH62727.1 - 0.48 10.4 9.0 0.71 9.8 9.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit AAA_18 PF13238.6 KXH62727.1 - 1.2 9.7 0.0 1.2 9.7 0.0 2.8 3 0 0 3 3 2 0 AAA domain DUF3295 PF11702.8 KXH62727.1 - 2 7.7 14.6 2.9 7.1 14.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) RRN3 PF05327.11 KXH62727.1 - 2.7 6.4 8.7 5.1 5.5 8.7 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 BUD22 PF09073.10 KXH62727.1 - 2.9 7.1 11.5 0.18 11.1 6.2 1.6 2 0 0 2 2 2 0 BUD22 Roughex PF06020.11 KXH62727.1 - 4.9 6.1 10.3 7.7 5.5 10.3 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Glyco_hydro_61 PF03443.14 KXH62728.1 - 1.2e-54 185.4 0.1 1.6e-54 184.9 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 MG2 PF01835.19 KXH62728.1 - 0.023 15.1 0.0 0.042 14.3 0.0 1.4 1 0 0 1 1 1 0 MG2 domain HET PF06985.11 KXH62729.1 - 5.1e-19 69.1 0.1 1.1e-16 61.5 0.1 2.5 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) GAF_2 PF13185.6 KXH62729.1 - 0.13 12.5 0.0 0.28 11.5 0.0 1.4 1 0 0 1 1 1 0 GAF domain Pyr_redox_3 PF13738.6 KXH62730.1 - 6.4e-18 65.0 0.0 2e-15 56.8 0.0 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXH62730.1 - 2.1e-14 53.4 0.0 2.6e-12 46.6 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KXH62730.1 - 1.1e-12 47.1 0.3 4.8e-10 38.5 0.1 2.4 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KXH62730.1 - 1.7e-09 37.3 0.0 3.4e-06 26.4 0.0 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KXH62730.1 - 1.6e-06 28.2 0.0 6.7e-06 26.3 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KXH62730.1 - 3.1e-05 23.4 0.0 0.005 16.1 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain 2-Hacid_dh_C PF02826.19 KXH62730.1 - 5.8e-05 22.5 0.1 0.0019 17.6 0.1 2.2 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox PF00070.27 KXH62730.1 - 0.00018 22.0 0.0 1.5 9.5 0.0 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXH62730.1 - 0.0017 17.7 0.0 0.027 13.7 0.0 2.2 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 KXH62730.1 - 0.0041 15.9 0.1 0.012 14.4 0.1 1.8 2 0 0 2 2 2 1 HI0933-like protein 3HCDH_N PF02737.18 KXH62730.1 - 0.0042 17.0 0.2 0.94 9.3 0.0 2.3 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DAO PF01266.24 KXH62730.1 - 0.005 16.5 0.0 0.065 12.8 0.0 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KXH62730.1 - 0.0059 15.7 0.2 0.023 13.8 0.6 1.8 2 0 0 2 2 2 1 FAD binding domain SnoaL_2 PF12680.7 KXH62730.1 - 0.0097 16.5 0.0 0.033 14.8 0.0 1.8 1 1 0 1 1 1 1 SnoaL-like domain TrkA_N PF02254.18 KXH62730.1 - 0.015 15.6 0.1 0.13 12.5 0.0 2.2 2 0 0 2 2 2 0 TrkA-N domain IlvN PF07991.12 KXH62730.1 - 0.017 14.7 0.1 0.89 9.1 0.0 2.4 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Lycopene_cycl PF05834.12 KXH62730.1 - 0.017 14.2 0.0 0.03 13.4 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Shikimate_DH PF01488.20 KXH62730.1 - 0.017 15.2 0.0 7.1 6.7 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase SnoaL_4 PF13577.6 KXH62730.1 - 0.021 15.0 0.0 0.051 13.7 0.0 1.8 1 0 0 1 1 1 0 SnoaL-like domain NAD_binding_9 PF13454.6 KXH62730.1 - 0.057 13.4 0.0 0.52 10.3 0.0 2.4 3 0 0 3 3 3 0 FAD-NAD(P)-binding COX1 PF00115.20 KXH62731.1 - 0.95 8.2 17.0 0.034 13.0 0.7 2.1 1 1 1 2 2 2 0 Cytochrome C and Quinol oxidase polypeptide I 2TM PF13239.6 KXH62731.1 - 2.2 8.6 3.9 3.2 8.1 1.6 2.3 2 0 0 2 2 2 0 2TM domain DUF917 PF06032.12 KXH62732.1 - 1.2e-126 422.3 2.6 1.2e-126 422.3 0.1 2.1 2 1 1 3 3 3 1 Protein of unknown function (DUF917) Hydantoinase_A PF01968.18 KXH62732.1 - 2.9e-28 99.0 5.0 2.9e-28 98.9 2.5 2.0 1 1 1 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 KXH62732.1 - 3e-15 56.4 2.7 2.3e-14 53.5 0.1 2.9 3 0 0 3 3 3 1 Hydantoinase/oxoprolinase N-terminal region FtsA PF14450.6 KXH62732.1 - 0.97 9.9 4.3 36 4.8 0.1 3.4 2 1 0 2 2 2 0 Cell division protein FtsA Transp_cyt_pur PF02133.15 KXH62733.1 - 1e-100 337.6 29.9 1.1e-100 337.4 29.9 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Tyrosinase PF00264.20 KXH62734.1 - 7.4e-49 167.0 0.0 1.1e-48 166.5 0.0 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase DUF1190 PF06693.11 KXH62735.1 - 0.026 14.9 0.3 0.039 14.3 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1190) MFS_1 PF07690.16 KXH62736.1 - 3.2e-40 138.2 26.4 4.1e-40 137.8 26.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH62736.1 - 1.2e-08 34.3 9.5 2.4e-08 33.3 8.7 1.8 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.6 KXH62736.1 - 0.28 9.7 17.9 0.0051 15.4 8.5 2.3 2 1 1 3 3 3 0 MFS/sugar transport protein Lipase_GDSL_2 PF13472.6 KXH62737.1 - 1.1e-13 51.9 0.5 1.5e-13 51.6 0.5 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KXH62737.1 - 1.4e-05 25.2 0.0 1.8e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DHquinase_I PF01487.15 KXH62737.1 - 0.047 13.9 0.0 0.065 13.5 0.0 1.1 1 0 0 1 1 1 0 Type I 3-dehydroquinase DUF3328 PF11807.8 KXH62738.1 - 1.6e-35 122.9 0.3 2.3e-35 122.4 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) CBP_BcsF PF11120.8 KXH62739.1 - 0.0034 17.5 1.4 54 4.0 0.0 4.5 5 0 0 5 5 5 0 Cellulose biosynthesis protein BcsF PGA_cap PF09587.10 KXH62739.1 - 0.0065 15.9 1.5 0.22 10.9 0.2 2.2 1 1 1 2 2 2 2 Bacterial capsule synthesis protein PGA_cap COX_ARM PF06481.14 KXH62739.1 - 0.044 13.7 0.2 35 4.4 0.0 3.2 3 0 0 3 3 3 0 COX Aromatic Rich Motif GGA_N-GAT PF18308.1 KXH62739.1 - 0.098 12.3 3.5 48 3.7 0.1 3.8 3 0 0 3 3 3 0 GGA N-GAT domain DUF3048_C PF17479.2 KXH62739.1 - 0.28 11.6 3.3 15 6.0 0.3 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3048) C-terminal domain PAS_6 PF08348.11 KXH62739.1 - 0.87 9.5 5.4 24 4.8 0.1 3.2 1 1 3 4 4 4 0 YheO-like PAS domain Glyco_transf_28 PF03033.20 KXH62740.1 - 2.2e-20 73.1 0.0 5.2e-20 71.9 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 KXH62740.1 - 3.6e-05 22.7 0.0 5.9e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 KXH62740.1 - 0.15 12.1 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain ketoacyl-synt PF00109.26 KXH62741.1 - 1.4e-74 250.9 0.4 2.8e-74 249.9 0.0 1.8 2 0 0 2 2 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KXH62741.1 - 5e-58 196.0 0.2 5e-58 196.0 0.2 2.6 3 0 0 3 3 2 1 KR domain PS-DH PF14765.6 KXH62741.1 - 9.8e-56 189.2 0.2 1.8e-55 188.3 0.2 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 KXH62741.1 - 5.8e-47 160.8 0.2 2.2e-46 158.9 0.2 1.9 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KXH62741.1 - 2.8e-34 117.7 0.5 1e-33 115.9 0.0 2.3 3 0 0 3 3 2 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 KXH62741.1 - 9.9e-21 74.3 0.0 3.3e-20 72.7 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 KXH62741.1 - 1.8e-17 63.4 1.3 2.2e-12 46.8 0.1 3.0 2 1 1 3 3 3 2 short chain dehydrogenase KAsynt_C_assoc PF16197.5 KXH62741.1 - 3.6e-14 53.2 0.0 2.8e-13 50.3 0.0 2.4 1 1 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_25 PF13649.6 KXH62741.1 - 1.8e-13 51.0 0.1 1.7e-12 47.8 0.0 2.9 3 0 0 3 3 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXH62741.1 - 4.4e-12 46.1 0.0 1.7e-11 44.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH62741.1 - 1e-10 42.1 0.0 4.7e-10 40.0 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH62741.1 - 3.3e-10 40.0 0.0 8.4e-10 38.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain adh_short_C2 PF13561.6 KXH62741.1 - 1.4e-09 37.9 0.7 6.5e-07 29.1 0.1 2.8 3 0 0 3 3 3 2 Enoyl-(Acyl carrier protein) reductase PP-binding PF00550.25 KXH62741.1 - 7.8e-09 35.8 0.3 2.3e-08 34.3 0.3 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_zinc_N PF00107.26 KXH62741.1 - 1.3e-08 34.8 0.0 5.7e-08 32.8 0.0 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Ubie_methyltran PF01209.18 KXH62741.1 - 6.1e-06 25.7 0.0 1.2e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Thiolase_N PF00108.23 KXH62741.1 - 0.00019 20.9 0.2 0.0013 18.2 0.0 2.3 2 0 0 2 2 2 1 Thiolase, N-terminal domain ADH_zinc_N_2 PF13602.6 KXH62741.1 - 0.0012 19.9 0.0 0.01 16.9 0.0 2.8 3 0 0 3 3 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXH62741.1 - 0.0012 18.7 0.1 0.0029 17.4 0.1 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PCMT PF01135.19 KXH62741.1 - 0.004 16.9 0.0 0.011 15.5 0.0 1.7 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 KXH62742.1 - 1.1e-09 38.3 0.0 1.6e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH62742.1 - 0.00089 19.9 0.0 0.0019 18.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH62742.1 - 0.0034 17.2 0.0 0.0092 15.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH62742.1 - 0.0039 17.8 0.0 0.0075 16.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH62742.1 - 0.009 16.7 0.0 0.024 15.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain CT47 PF15623.6 KXH62742.1 - 0.21 11.4 3.1 0.32 10.8 3.1 1.2 1 0 0 1 1 1 0 Cancer/testis gene family 47 Methyltransf_25 PF13649.6 KXH62743.1 - 2.9e-06 27.9 0.0 5e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH62743.1 - 4.8e-06 27.2 0.0 9.6e-06 26.3 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXH62743.1 - 1.5e-05 24.9 0.0 1.9e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXH62743.1 - 0.022 14.3 0.0 0.041 13.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Sugar_tr PF00083.24 KXH62744.1 - 9.8e-92 308.2 26.7 1.2e-91 307.8 26.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH62744.1 - 6.9e-28 97.6 25.9 6.9e-28 97.6 25.9 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KXH62744.1 - 0.0014 17.2 2.8 0.0014 17.2 2.8 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) PT-VENN PF04829.13 KXH62744.1 - 0.012 15.7 0.7 0.039 14.0 0.7 1.9 1 0 0 1 1 1 0 Pre-toxin domain with VENN motif DUF1385 PF07136.11 KXH62744.1 - 0.38 10.0 4.3 0.44 9.8 0.9 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1385) Glyco_hydro_11 PF00457.17 KXH62745.1 - 1.9e-82 275.2 20.7 2.3e-82 275.0 20.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 Ank_2 PF12796.7 KXH62746.1 - 1.8e-14 54.1 0.0 9.6e-05 22.9 0.0 3.6 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXH62746.1 - 7e-12 44.4 0.1 0.16 12.6 0.0 6.0 7 0 0 7 7 7 3 Ankyrin repeat Ank_5 PF13857.6 KXH62746.1 - 3.4e-09 36.8 0.3 0.045 14.1 0.0 4.5 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXH62746.1 - 1.2e-08 35.3 0.4 0.0066 17.0 0.0 4.8 2 2 4 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.30 KXH62746.1 - 5.6e-08 32.9 0.7 2.4 8.8 0.0 5.3 6 0 0 6 6 6 3 Ankyrin repeat Ank_2 PF12796.7 KXH62747.1 - 1e-09 38.9 0.0 0.02 15.5 0.0 3.2 3 0 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXH62747.1 - 1.5e-09 37.9 0.0 0.1 13.0 0.0 4.0 3 1 0 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXH62747.1 - 2.4e-09 36.7 0.8 0.013 16.0 0.0 4.5 5 0 0 5 5 5 2 Ankyrin repeat Ank PF00023.30 KXH62747.1 - 6.4e-07 29.5 0.3 0.32 11.5 0.0 4.5 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 KXH62747.1 - 2.2e-06 28.1 0.2 0.23 12.1 0.0 4.3 3 1 1 4 4 4 3 Ankyrin repeats (many copies) F-box-like PF12937.7 KXH62748.1 - 0.00019 21.2 0.2 0.00064 19.6 0.2 1.9 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KXH62748.1 - 0.00072 19.9 3.3 2.7 8.5 0.1 5.0 3 2 1 4 4 4 3 Leucine Rich repeats (2 copies) ADH_N_2 PF16884.5 KXH62749.1 - 2.3e-30 104.6 0.0 4.4e-30 103.8 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 KXH62749.1 - 1.6e-19 70.2 0.0 2.5e-19 69.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXH62749.1 - 9.1e-07 30.0 0.0 1.7e-06 29.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PCP_red PF08369.10 KXH62750.1 - 0.011 15.9 1.9 0.016 15.4 0.6 1.9 2 0 0 2 2 2 0 Proto-chlorophyllide reductase 57 kD subunit Oxidored_FMN PF00724.20 KXH62751.1 - 4.6e-91 305.6 0.0 5.3e-91 305.4 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family PRAI PF00697.22 KXH62751.1 - 0.21 11.3 0.0 0.47 10.2 0.0 1.5 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase MFS_1 PF07690.16 KXH62752.1 - 3.4e-37 128.2 45.5 1.1e-35 123.2 45.5 2.9 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KXH62752.1 - 1.1e-18 67.0 9.4 1.8e-18 66.3 9.4 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KXH62752.1 - 1.2e-09 37.6 12.4 1.2e-09 37.6 12.4 3.3 3 1 0 3 3 3 2 Sugar (and other) transporter VirB8 PF04335.13 KXH62752.1 - 0.22 11.3 0.2 1.9 8.2 0.1 2.3 2 0 0 2 2 2 0 VirB8 protein Polysacc_deac_1 PF01522.21 KXH62753.1 - 9e-12 45.0 0.0 1.5e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Fungal_trans PF04082.18 KXH62754.1 - 6.1e-31 107.4 1.6 6.1e-31 107.4 1.6 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Transp_cyt_pur PF02133.15 KXH62755.1 - 1.3e-85 287.8 41.8 1.6e-85 287.6 41.8 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Amidase PF01425.21 KXH62756.1 - 8.9e-71 239.2 0.1 2.6e-70 237.6 0.1 1.7 1 1 0 1 1 1 1 Amidase Suv3_C_1 PF18147.1 KXH62757.1 - 0.08 12.8 0.1 0.16 11.8 0.1 1.5 1 0 0 1 1 1 0 Suv3 C-terminal domain 1 Aminotran_1_2 PF00155.21 KXH62758.1 - 2.8e-11 43.2 0.0 3.3e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 KXH62758.1 - 0.18 10.5 0.0 0.67 8.7 0.0 1.8 1 1 0 1 1 1 0 Alanine-glyoxylate amino-transferase mRNA_cap_C PF03919.15 KXH62759.1 - 0.14 12.8 0.0 0.29 11.8 0.0 1.5 1 0 0 1 1 1 0 mRNA capping enzyme, C-terminal domain TPP_enzyme_N PF02776.18 KXH62760.1 - 3.6e-29 101.6 0.3 5.2e-29 101.0 0.3 1.2 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KXH62760.1 - 2.2e-17 63.2 0.0 1.5e-16 60.6 0.0 2.2 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KXH62760.1 - 3.3e-16 59.3 0.0 6.7e-16 58.3 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain ADH_zinc_N PF00107.26 KXH62761.1 - 7.8e-12 45.3 0.0 1.3e-11 44.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXH62761.1 - 0.017 15.0 0.0 0.03 14.2 0.0 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 KXH62761.1 - 0.025 14.0 0.1 0.042 13.3 0.1 1.3 1 0 0 1 1 1 0 short chain dehydrogenase HET PF06985.11 KXH62762.1 - 5.8e-34 117.5 0.1 9.3e-34 116.9 0.1 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Zip PF02535.22 KXH62763.1 - 2.1e-29 102.8 40.0 2.3e-12 46.8 4.0 3.5 3 1 1 4 4 4 3 ZIP Zinc transporter MFS_1 PF07690.16 KXH62766.1 - 2e-28 99.3 17.9 2.6e-28 99.0 17.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH62766.1 - 3.3e-05 22.9 10.0 6.7e-05 21.9 10.0 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter DIOX_N PF14226.6 KXH62767.1 - 1.1e-15 58.4 0.0 2.7e-15 57.1 0.0 1.7 1 1 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KXH62767.1 - 8e-14 52.0 0.0 1.4e-13 51.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily HET PF06985.11 KXH62768.1 - 0.00023 21.5 0.3 0.00044 20.6 0.3 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) BNR PF02012.20 KXH62769.1 - 0.058 13.4 2.3 8.6 6.8 0.2 3.1 2 0 0 2 2 2 0 BNR/Asp-box repeat Tryp_inh PF17983.1 KXH62769.1 - 3.7 7.7 6.1 3.9 7.7 0.4 2.3 2 0 0 2 2 2 0 Trypsin inhibitors 1,2 and 3 TolA_bind_tri PF16331.5 KXH62770.1 - 0.048 13.7 2.5 5.7 7.1 0.2 2.9 2 0 0 2 2 2 0 TolA binding protein trimerisation BST2 PF16716.5 KXH62770.1 - 0.99 10.0 4.4 1.1 9.9 0.0 2.9 3 1 0 3 3 3 0 Bone marrow stromal antigen 2 GST_N_3 PF13417.6 KXH62771.1 - 3.8e-10 40.0 0.2 1.8e-09 37.9 0.1 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KXH62771.1 - 1.4e-09 38.1 0.0 2.2e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KXH62771.1 - 1.1e-08 35.2 0.0 2.4e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KXH62771.1 - 2e-05 24.7 0.0 0.00016 21.8 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KXH62771.1 - 3.9e-05 23.8 0.0 8.4e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KXH62771.1 - 0.0032 17.5 0.0 0.0083 16.1 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain FAA_hydrolase PF01557.18 KXH62772.1 - 1.5e-57 194.7 0.0 2.3e-57 194.2 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 KXH62772.1 - 2.6e-32 111.2 0.0 4.6e-32 110.4 0.0 1.4 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal Zn_clus PF00172.18 KXH62773.1 - 0.00091 19.3 7.6 0.0016 18.6 7.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RIC3 PF15361.6 KXH62773.1 - 0.095 13.1 0.2 0.24 11.8 0.0 1.8 2 0 0 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 Fungal_trans PF04082.18 KXH62774.1 - 7.7e-20 71.0 0.1 1.6e-19 70.0 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 KXH62775.1 - 1.1e-34 119.9 19.1 1.1e-34 119.9 19.1 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily APS_kinase PF01583.20 KXH62776.1 - 0.0023 17.8 0.0 0.0046 16.9 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.6 KXH62776.1 - 0.0031 17.7 0.0 0.006 16.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KXH62776.1 - 0.017 15.7 0.0 0.045 14.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain Torsin PF06309.11 KXH62776.1 - 0.023 14.8 0.0 0.12 12.5 0.0 2.0 2 0 0 2 2 2 0 Torsin AAA_16 PF13191.6 KXH62776.1 - 0.032 14.6 0.0 0.053 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain MeaB PF03308.16 KXH62776.1 - 0.045 12.7 0.0 0.065 12.2 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Zeta_toxin PF06414.12 KXH62776.1 - 0.064 12.5 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin NB-ARC PF00931.22 KXH62776.1 - 0.092 11.9 0.1 1.4 8.0 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain Iso_dh PF00180.20 KXH62777.1 - 6.5e-88 295.2 0.0 7.3e-88 295.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase SAM_2 PF07647.17 KXH62777.1 - 0.045 13.9 0.0 0.13 12.4 0.0 1.8 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) DUF4875 PF16175.5 KXH62777.1 - 0.059 13.5 0.1 0.26 11.4 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4875) MFS_Mycoplasma PF07672.13 KXH62778.1 - 0.0076 15.6 0.3 0.0076 15.6 0.3 2.0 2 0 0 2 2 2 1 Mycoplasma MFS transporter MFS_1 PF07690.16 KXH62779.1 - 1.9e-31 109.3 39.5 3.2e-31 108.6 39.0 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 KXH62779.1 - 0.0081 15.5 17.9 0.033 13.5 5.3 2.2 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB FixQ PF05545.11 KXH62779.1 - 2 8.4 0.0 2 8.4 0.0 3.5 3 0 0 3 3 3 0 Cbb3-type cytochrome oxidase component FixQ DUF1516 PF07457.11 KXH62779.1 - 5.5 7.2 9.1 1.1 9.5 0.6 3.3 2 1 0 3 3 3 0 Protein of unknown function (DUF1516) Shisa PF13908.6 KXH62780.1 - 5.2 7.3 12.2 38 4.4 12.2 2.3 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator ISN1 PF06437.11 KXH62806.1 - 4.2e-103 345.4 0.0 4.8e-103 345.2 0.0 1.0 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase Herpes_DNAp_acc PF04929.12 KXH62814.1 - 0.05 12.6 4.3 0.07 12.1 4.3 1.3 1 0 0 1 1 1 0 Herpes DNA replication accessory factor SOG2 PF10428.9 KXH62814.1 - 0.39 9.9 15.0 0.44 9.7 15.0 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein hDGE_amylase PF14701.6 KXH62815.1 - 6.9e-180 598.8 0.0 8.7e-180 598.5 0.0 1.1 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain GDE_C PF06202.14 KXH62815.1 - 6.1e-117 390.8 0.2 1.1e-116 389.9 0.0 1.5 2 0 0 2 2 2 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.6 KXH62815.1 - 2.5e-89 299.3 0.0 1.2e-88 297.0 0.0 2.1 2 0 0 2 2 2 1 Central domain of human glycogen debranching enzyme hGDE_N PF14699.6 KXH62815.1 - 1.1e-30 105.6 0.0 2.6e-30 104.4 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme DUF4381 PF14316.6 KXH62817.1 - 0.03 14.6 0.8 0.045 14.0 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) UPF0370 PF13980.6 KXH62817.1 - 0.07 13.2 2.8 0.11 12.6 2.8 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0370) RCR PF12273.8 KXH62817.1 - 0.4 11.4 3.6 0.87 10.3 3.6 1.7 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red DUF4231 PF14015.6 KXH62817.1 - 2.4 8.7 5.1 5.2 7.6 5.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF4231) RGS PF00615.19 KXH62818.1 - 0.0006 20.1 0.0 0.0023 18.2 0.0 1.9 1 1 0 1 1 1 1 Regulator of G protein signaling domain Meth_synt_2 PF01717.18 KXH62819.1 - 4.3e-09 36.1 0.0 7.9e-08 31.9 0.0 2.5 2 1 0 2 2 2 1 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 KXH62819.1 - 0.0018 17.9 0.1 0.008 15.7 0.0 2.1 3 0 0 3 3 3 1 Cobalamin-independent synthase, N-terminal domain Epimerase PF01370.21 KXH62822.1 - 1e-09 38.3 0.1 4.7e-09 36.1 0.1 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXH62822.1 - 1.3e-06 27.7 0.0 1.9e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KXH62822.1 - 2.4e-06 27.6 0.0 3.5e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KXH62822.1 - 4e-06 26.2 0.0 0.0002 20.6 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 KXH62822.1 - 1e-05 25.1 0.1 3.1e-05 23.6 0.0 1.9 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 KXH62822.1 - 0.00021 21.0 0.0 0.00029 20.5 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.25 KXH62822.1 - 0.037 13.5 0.0 0.13 11.7 0.0 1.9 2 0 0 2 2 2 0 short chain dehydrogenase KR PF08659.10 KXH62822.1 - 0.053 13.4 0.1 11 5.9 0.0 2.2 2 0 0 2 2 2 0 KR domain OPT PF03169.15 KXH62823.1 - 5.6e-162 540.6 42.4 6.4e-162 540.4 42.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein MFS_1 PF07690.16 KXH62824.1 - 1.6e-20 73.4 57.4 1.5e-10 40.6 24.6 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Csd3_N PF18059.1 KXH62824.1 - 0.055 14.0 0.0 0.11 13.0 0.0 1.5 1 0 0 1 1 1 0 Csd3 N-terminal PolyG_pol PF01518.16 KXH62824.1 - 0.088 11.5 0.1 0.14 10.8 0.1 1.2 1 0 0 1 1 1 0 Sigma NS protein ADH_zinc_N PF00107.26 KXH62825.1 - 5.4e-14 52.3 0.0 8.7e-14 51.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXH62825.1 - 7.1e-14 53.0 0.0 1.4e-13 52.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXH62825.1 - 4.8e-06 26.4 0.1 2.4e-05 24.2 0.0 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Epimerase PF01370.21 KXH62825.1 - 0.019 14.5 0.0 0.027 13.9 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family PEP-utilizers_C PF02896.18 KXH62825.1 - 0.019 14.1 0.0 0.028 13.5 0.0 1.1 1 0 0 1 1 1 0 PEP-utilising enzyme, TIM barrel domain Abhydrolase_4 PF08386.10 KXH62826.1 - 2e-18 66.4 0.0 4.8e-18 65.2 0.0 1.7 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.20 KXH62826.1 - 6.6e-09 35.8 0.0 4.1e-07 29.9 0.0 2.8 2 1 0 2 2 2 1 alpha/beta hydrolase fold MLTR_LBD PF17765.1 KXH62826.1 - 0.13 12.4 0.1 24 5.0 0.0 2.5 2 0 0 2 2 2 0 MmyB-like transcription regulator ligand binding domain Tannase PF07519.11 KXH62828.1 - 4.1e-81 273.3 1.9 5.3e-81 272.9 1.9 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Fungal_trans_2 PF11951.8 KXH62828.1 - 1.5e-06 27.3 0.0 2.4e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Peptidase_S9 PF00326.21 KXH62828.1 - 0.0012 18.4 0.0 0.042 13.3 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family Zn_clus PF00172.18 KXH62828.1 - 0.75 10.0 4.0 1.6 8.9 4.0 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_1 PF00561.20 KXH62829.1 - 1.7e-16 60.7 0.0 2.4e-16 60.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXH62829.1 - 2e-06 28.6 0.0 2.5e-06 28.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXH62829.1 - 2e-05 24.0 0.0 3.1e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Esterase PF00756.20 KXH62829.1 - 0.00098 18.8 0.0 0.0018 18.0 0.0 1.4 1 0 0 1 1 1 1 Putative esterase PGAP1 PF07819.13 KXH62829.1 - 0.037 13.8 0.0 3.8 7.2 0.0 2.1 1 1 0 2 2 2 0 PGAP1-like protein Peptidase_S28 PF05577.12 KXH62829.1 - 0.037 12.8 0.0 0.049 12.4 0.0 1.1 1 0 0 1 1 1 0 Serine carboxypeptidase S28 DUF3425 PF11905.8 KXH62830.1 - 9.1e-24 83.8 0.0 1.6e-23 83.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) Glyco_hydro_7 PF00840.20 KXH62831.1 - 2e-185 616.7 7.7 2.2e-185 616.5 7.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Gamma-thionin PF00304.20 KXH62831.1 - 0.077 13.3 0.7 0.077 13.3 0.7 3.1 4 0 0 4 4 4 0 Gamma-thionin family DUF5013 PF16405.5 KXH62831.1 - 0.078 13.3 0.3 0.14 12.4 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5013) MFS_1 PF07690.16 KXH62832.1 - 8.9e-35 120.2 56.8 1.3e-25 90.1 33.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2304 PF10066.9 KXH62832.1 - 0.17 12.1 1.1 0.58 10.4 0.1 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) DLH PF01738.18 KXH62833.1 - 1.8e-24 86.5 0.0 2.4e-24 86.1 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 KXH62833.1 - 1.9e-05 24.5 0.0 7.1e-05 22.6 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Chlorophyllase PF07224.11 KXH62833.1 - 0.0011 18.0 0.0 0.0015 17.6 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase Fungal_trans_2 PF11951.8 KXH62834.1 - 0.0011 17.9 2.9 0.0018 17.2 2.9 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 KXH62835.1 - 7.2e-32 110.7 27.4 9e-32 110.3 24.5 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily DivIC PF04977.15 KXH62835.1 - 0.12 12.2 0.0 0.28 11.0 0.0 1.6 1 0 0 1 1 1 0 Septum formation initiator PhoLip_ATPase_C PF16212.5 KXH62835.1 - 1.4 8.6 11.5 0.046 13.5 3.2 2.5 3 0 0 3 3 3 0 Phospholipid-translocating P-type ATPase C-terminal Fungal_trans_2 PF11951.8 KXH62836.1 - 4.1e-07 29.2 0.2 6e-07 28.6 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pap_E4 PF02711.14 KXH62836.1 - 3.9 8.5 8.8 9.5 7.3 8.8 1.6 1 0 0 1 1 1 0 E4 protein Glyco_hydro_76 PF03663.14 KXH62838.1 - 2.5e-123 412.2 8.9 3.1e-123 411.9 8.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 BCS1_N PF08740.11 KXH62839.1 - 1.1e-36 126.5 1.7 1.8e-36 125.9 0.1 1.9 2 0 0 2 2 2 1 BCS1 N terminal AAA PF00004.29 KXH62839.1 - 1.5e-17 64.3 0.0 8.5e-17 61.8 0.0 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KXH62839.1 - 9.6e-06 25.4 0.0 1.8e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_11 PF13086.6 KXH62839.1 - 0.0015 18.4 0.5 0.32 10.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KXH62839.1 - 0.02 15.3 0.0 0.082 13.3 0.0 2.1 1 1 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.14 KXH62839.1 - 0.024 14.7 0.0 0.14 12.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) ATPase PF06745.13 KXH62839.1 - 0.06 12.7 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_24 PF13479.6 KXH62839.1 - 0.066 12.9 0.3 2.1 8.0 0.1 2.4 1 1 1 2 2 2 0 AAA domain AAA_18 PF13238.6 KXH62839.1 - 0.067 13.7 0.1 0.29 11.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 KXH62839.1 - 0.1 12.3 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein PrmC_N PF17827.1 KXH62839.1 - 0.18 12.4 1.0 30 5.3 0.0 3.0 3 0 0 3 3 3 0 PrmC N-terminal domain Hydin_ADK PF17213.3 KXH62839.1 - 0.32 11.3 7.4 30 4.8 0.0 2.3 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain AAA_13 PF13166.6 KXH62839.1 - 3.8 6.1 8.4 1.1 7.9 0.1 2.1 2 0 0 2 2 2 0 AAA domain Abhydrolase_6 PF12697.7 KXH62840.1 - 2.8e-17 64.1 0.0 3.6e-17 63.7 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF900 PF05990.12 KXH62840.1 - 0.009 15.5 0.0 0.024 14.2 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF900) Hydrolase_4 PF12146.8 KXH62840.1 - 0.076 12.3 0.0 0.085 12.1 0.0 1.4 1 1 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_8 PF06259.12 KXH62840.1 - 0.094 12.3 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase DUF676 PF05057.14 KXH62840.1 - 0.2 11.1 0.0 0.26 10.7 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) HET PF06985.11 KXH62841.1 - 2.8e-26 92.6 0.8 4.8e-26 91.9 0.2 1.8 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) ADC PF06314.11 KXH62842.1 - 0.00048 19.8 0.0 0.00073 19.2 0.0 1.3 1 0 0 1 1 1 1 Acetoacetate decarboxylase (ADC) HET PF06985.11 KXH62843.1 - 3.8e-38 131.1 0.8 6.3e-38 130.4 0.8 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Inhibitor_I9 PF05922.16 KXH62844.1 - 0.019 15.6 0.0 0.048 14.3 0.0 1.7 1 0 0 1 1 1 0 Peptidase inhibitor I9 p450 PF00067.22 KXH62845.1 - 2e-69 234.6 0.0 2.5e-69 234.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DDE_Tnp_IS66_C PF13817.6 KXH62846.1 - 0.091 13.0 0.4 12 6.2 0.0 2.4 2 0 0 2 2 2 0 IS66 C-terminal element Oxidored_q6 PF01058.22 KXH62847.1 - 2.1e-22 79.3 0.0 3e-22 78.9 0.0 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit WBS_methylT PF12589.8 KXH62848.1 - 1.8e-16 60.7 6.9 3.3e-16 59.8 6.9 1.5 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.12 KXH62848.1 - 6.2e-12 46.0 0.0 1.2e-11 45.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH62848.1 - 6.9e-11 42.7 0.0 1.9e-10 41.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH62848.1 - 1.8e-05 25.4 0.0 8.1e-05 23.3 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain PCMT PF01135.19 KXH62848.1 - 0.00087 19.1 0.0 0.0014 18.4 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 KXH62848.1 - 0.001 18.9 0.0 0.0015 18.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXH62848.1 - 0.0024 17.7 0.0 0.0038 17.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KXH62848.1 - 0.0025 17.1 0.0 0.06 12.6 0.0 2.1 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 KXH62848.1 - 0.038 13.3 0.0 0.12 11.7 0.0 1.8 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 KXH62848.1 - 0.11 11.8 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_33 PF10017.9 KXH62848.1 - 0.16 11.0 0.0 0.24 10.5 0.0 1.2 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent Erv26 PF04148.13 KXH62849.1 - 2.6e-93 311.6 3.5 3.1e-93 311.3 3.5 1.0 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 Cytochrom_C_asm PF01578.20 KXH62849.1 - 0.0029 17.4 0.2 0.0029 17.4 0.2 1.7 3 0 0 3 3 3 1 Cytochrome C assembly protein DUF3377 PF11857.8 KXH62849.1 - 0.014 15.3 0.8 0.37 10.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) adh_short PF00106.25 KXH62851.1 - 2.6e-25 89.0 0.0 9.3e-19 67.7 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXH62851.1 - 9.6e-15 54.8 0.0 5.9e-14 52.2 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH62851.1 - 0.00027 20.9 0.0 0.00043 20.2 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KXH62851.1 - 0.016 14.4 0.0 0.022 13.9 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Dynamin_N PF00350.23 KXH62852.1 - 9.9e-32 110.3 0.0 2.5e-31 109.0 0.0 1.7 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 KXH62852.1 - 2.8e-15 56.3 0.0 2.2e-14 53.4 0.0 2.2 1 1 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.23 KXH62852.1 - 2.1e-05 24.6 0.1 8.3e-05 22.6 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase ABC_tran PF00005.27 KXH62852.1 - 0.053 14.0 0.0 0.18 12.3 0.0 1.9 1 0 0 1 1 1 0 ABC transporter VPS13_C PF16909.5 KXH62852.1 - 0.16 11.8 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 Vacuolar-sorting-associated 13 protein C-terminal AAA_15 PF13175.6 KXH62852.1 - 0.23 11.1 1.4 0.98 9.1 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain ADH_zinc_N PF00107.26 KXH62853.1 - 7.5e-20 71.2 0.0 1.1e-19 70.7 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KXH62853.1 - 1.1e-19 70.3 0.0 4.3e-19 68.4 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 KXH62853.1 - 4.2e-09 37.5 0.0 7.3e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TetR_N PF00440.23 KXH62854.1 - 0.035 13.9 0.6 2.3 8.1 0.1 2.6 2 0 0 2 2 2 0 Bacterial regulatory proteins, tetR family NAAA-beta PF15508.6 KXH62855.1 - 6.5e-11 42.4 0.0 1.3e-10 41.4 0.0 1.6 1 0 0 1 1 1 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase p450 PF00067.22 KXH62856.1 - 3.3e-58 197.6 0.0 4.6e-58 197.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Iso_dh PF00180.20 KXH62858.1 - 3.6e-82 276.3 0.1 4.1e-82 276.1 0.1 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Methyltransf_11 PF08241.12 KXH62860.1 - 2.1e-20 73.2 0.0 4.3e-20 72.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH62860.1 - 3.3e-19 69.4 0.0 7e-19 68.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH62860.1 - 3.2e-17 62.7 0.0 4.8e-17 62.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXH62860.1 - 2e-13 50.5 0.0 3e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH62860.1 - 4e-11 43.5 0.0 8.2e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KXH62860.1 - 5.5e-11 42.3 0.0 7.4e-11 41.8 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 KXH62860.1 - 3.3e-10 39.7 0.0 1.9e-09 37.2 0.0 1.9 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KXH62860.1 - 3.4e-05 23.5 0.0 5.5e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain MetW PF07021.12 KXH62860.1 - 3.5e-05 23.5 0.0 5.8e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW TehB PF03848.14 KXH62860.1 - 0.00031 20.2 0.0 0.00057 19.4 0.0 1.4 1 0 0 1 1 1 1 Tellurite resistance protein TehB PCMT PF01135.19 KXH62860.1 - 0.0011 18.8 0.0 0.0019 18.0 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 KXH62860.1 - 0.0013 18.2 0.0 0.0018 17.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_8 PF05148.15 KXH62860.1 - 0.0052 16.7 0.0 0.072 12.9 0.0 2.2 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_2 PF00891.18 KXH62860.1 - 0.022 14.1 0.0 0.042 13.1 0.0 1.5 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_4 PF02390.17 KXH62860.1 - 0.027 14.0 0.0 0.081 12.4 0.0 1.8 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_32 PF13679.6 KXH62860.1 - 0.031 14.2 0.0 0.057 13.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DREV PF05219.12 KXH62860.1 - 0.042 12.9 0.0 0.074 12.1 0.0 1.4 1 0 0 1 1 1 0 DREV methyltransferase DOT1 PF08123.13 KXH62860.1 - 0.051 13.1 0.0 0.081 12.4 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltr_RsmB-F PF01189.17 KXH62860.1 - 0.063 12.9 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F RrnaAD PF00398.20 KXH62860.1 - 0.15 11.1 0.0 0.24 10.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase TPR_12 PF13424.6 KXH62888.1 - 3.1e-06 27.4 1.4 0.00023 21.4 0.8 2.7 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 KXH62888.1 - 0.17 12.1 2.8 0.49 10.6 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 KXH62888.1 - 0.33 10.9 1.3 2.4 8.1 0.1 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3295 PF11702.8 KXH62891.1 - 2.1e-58 199.0 15.1 3.6e-58 198.1 15.1 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3295) AMP-binding PF00501.28 KXH62892.1 - 4.1e-224 743.8 0.0 1.2e-76 258.1 0.0 3.5 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.20 KXH62892.1 - 1.1e-187 624.3 1.6 2.1e-35 122.3 0.1 7.3 6 2 0 6 6 6 6 Condensation domain PP-binding PF00550.25 KXH62892.1 - 9.4e-55 182.9 20.7 5.2e-11 42.7 0.2 7.7 8 0 0 8 8 8 6 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KXH62892.1 - 8e-11 42.8 0.0 0.0094 16.9 0.0 4.2 3 0 0 3 3 3 3 AMP-binding enzyme C-terminal domain Transferase PF02458.15 KXH62892.1 - 1.7e-08 33.6 0.0 0.23 10.1 0.0 5.4 6 0 0 6 6 6 3 Transferase family WES_acyltransf PF03007.16 KXH62892.1 - 3.1e-06 27.2 1.2 1 9.1 0.0 5.6 6 0 0 6 6 6 2 Wax ester synthase-like Acyl-CoA acyltransferase domain Peptidase_M36 PF02128.15 KXH62893.1 - 1.5e-161 537.7 2.6 2e-161 537.3 2.6 1.1 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.13 KXH62893.1 - 1.8e-17 62.9 5.6 1.8e-17 62.9 5.6 2.3 3 0 0 3 3 3 1 Fungalysin/Thermolysin Propeptide Motif Peptidase_M4_C PF02868.15 KXH62893.1 - 0.022 14.6 0.0 0.048 13.5 0.0 1.6 1 0 0 1 1 1 0 Thermolysin metallopeptidase, alpha-helical domain Goodbye PF17109.5 KXH62894.1 - 2.2e-23 83.0 0.0 6.1e-23 81.6 0.0 1.8 1 0 0 1 1 1 1 fungal STAND N-terminal Goodbye domain NACHT PF05729.12 KXH62894.1 - 0.031 14.2 0.0 0.086 12.8 0.0 1.8 1 0 0 1 1 1 0 NACHT domain Endonuc_Holl PF10107.9 KXH62894.1 - 0.059 13.2 0.6 0.19 11.6 0.6 1.9 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase Dis3l2_C_term PF17877.1 KXH62894.1 - 0.15 12.4 0.0 0.51 10.7 0.0 1.9 1 0 0 1 1 1 0 DIS3-like exonuclease 2 C terminal FliT PF05400.13 KXH62894.1 - 0.95 10.3 5.3 7.1 7.5 0.2 3.9 3 0 0 3 3 3 0 Flagellar protein FliT DUF3176 PF11374.8 KXH62895.1 - 5.9e-29 100.4 2.8 1.8e-28 98.9 1.7 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) NiFe_hyd_3_EhaA PF17367.2 KXH62895.1 - 0.12 12.5 0.7 0.32 11.2 0.7 1.7 1 0 0 1 1 1 0 NiFe-hydrogenase-type-3 Eha complex subunit A RTA1 PF04479.13 KXH62896.1 - 2e-69 233.3 7.3 2e-69 233.3 7.3 1.5 2 0 0 2 2 2 1 RTA1 like protein Cpta_toxin PF07254.12 KXH62896.1 - 0.049 13.6 0.2 4.1 7.4 0.0 2.7 1 1 1 2 2 2 0 Membrane-bound toxin component of toxin-antitoxin system Zn_clus PF00172.18 KXH62897.1 - 5.6e-08 32.8 9.9 9.6e-08 32.0 9.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KXH62897.1 - 9.1e-05 21.4 5.4 9.1e-05 21.4 5.4 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF2264 PF10022.9 KXH62898.1 - 5.3e-133 443.5 0.4 7.8e-133 442.9 0.4 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) IBR PF01485.21 KXH62899.1 - 0.0012 19.0 7.6 0.0012 19.0 7.6 6.0 4 2 1 5 5 5 2 IBR domain, a half RING-finger domain PI-PLC-C1 PF16670.5 KXH62900.1 - 1.4e-132 441.7 0.0 1.7e-132 441.5 0.0 1.0 1 0 0 1 1 1 1 Phosphoinositide phospholipase C, Ca2+-dependent DUF4185 PF13810.6 KXH62901.1 - 2.7e-13 49.9 1.3 4.6e-13 49.1 1.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4185) Glyco_hydro_43 PF04616.14 KXH62901.1 - 0.0037 16.6 0.2 0.11 11.8 0.0 2.3 1 1 1 2 2 2 2 Glycosyl hydrolases family 43 bZIP_1 PF00170.21 KXH62902.1 - 5.2e-07 29.7 4.9 1.2e-06 28.5 4.9 1.5 1 0 0 1 1 1 1 bZIP transcription factor WDCP PF15390.6 KXH62902.1 - 1.1 7.5 5.3 2.1 6.6 5.3 1.3 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family Complex1_LYR PF05347.15 KXH62903.1 - 2.8e-06 27.3 0.1 1.5e-05 24.9 0.1 2.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) DUF3669 PF12417.8 KXH62904.1 - 4.2e-27 94.1 0.2 1.5e-26 92.3 0.1 1.9 2 0 0 2 2 2 1 Zinc finger protein DUF3669 PF12417.8 KXH62905.1 - 3.3e-16 59.2 0.0 6.9e-16 58.2 0.0 1.6 1 0 0 1 1 1 1 Zinc finger protein OGG_N PF07934.12 KXH62906.1 - 0.079 13.0 0.6 0.12 12.5 0.6 1.4 1 0 0 1 1 1 0 8-oxoguanine DNA glycosylase, N-terminal domain PRANC PF09372.10 KXH62906.1 - 0.087 13.2 0.0 0.24 11.7 0.0 1.7 1 0 0 1 1 1 0 PRANC domain DUF1143 PF06608.11 KXH62906.1 - 0.45 10.6 3.2 3 7.9 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1143) adh_short_C2 PF13561.6 KXH62907.1 - 1.6e-31 109.7 1.4 2.1e-31 109.3 1.4 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXH62907.1 - 7.3e-24 84.3 0.1 1.1e-23 83.7 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXH62907.1 - 0.00022 21.2 0.2 0.00033 20.6 0.2 1.3 1 0 0 1 1 1 1 KR domain Phage_TAC_10 PF10963.8 KXH62907.1 - 0.14 12.4 0.1 0.26 11.5 0.1 1.5 1 0 0 1 1 1 0 Phage tail assembly chaperone DUF4334 PF14232.6 KXH62908.1 - 8.1e-29 99.4 1.5 2e-28 98.1 0.9 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4334) GXWXG PF14231.6 KXH62908.1 - 9.1e-24 83.3 0.1 1.6e-23 82.5 0.1 1.4 1 0 0 1 1 1 1 GXWXG protein FAD_binding_4 PF01565.23 KXH62908.1 - 8.7e-15 54.7 0.0 1.4e-14 54.0 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Ndc80_HEC PF03801.13 KXH62908.1 - 0.12 12.0 0.0 0.33 10.6 0.0 1.7 1 1 0 1 1 1 0 HEC/Ndc80p family DUF2427 PF10348.9 KXH62909.1 - 0.0014 18.4 0.5 0.0058 16.4 0.5 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF2427) DUF2269 PF10027.9 KXH62909.1 - 1.9 8.5 5.7 1.5 8.8 0.5 2.4 1 1 1 2 2 2 0 Predicted integral membrane protein (DUF2269) FAD_binding_4 PF01565.23 KXH62910.1 - 7.1e-24 84.1 0.1 1.3e-23 83.2 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KXH62910.1 - 0.007 16.4 0.1 0.007 16.4 0.1 2.7 3 0 0 3 3 3 1 Berberine and berberine like Nuc_sug_transp PF04142.15 KXH62911.1 - 2.4e-104 348.9 8.4 3.5e-104 348.3 8.4 1.2 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.11 KXH62911.1 - 1.9e-07 30.6 6.9 8e-05 22.0 2.6 2.2 2 0 0 2 2 2 2 UAA transporter family EamA PF00892.20 KXH62911.1 - 9.5e-07 29.1 25.8 0.0008 19.6 4.3 2.5 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 KXH62911.1 - 0.0018 17.7 14.1 0.063 12.6 6.0 2.3 2 0 0 2 2 2 2 Triose-phosphate Transporter family DUF2306 PF10067.9 KXH62911.1 - 0.19 11.9 5.4 0.56 10.4 5.4 1.8 1 0 0 1 1 1 0 Predicted membrane protein (DUF2306) DMT_6 PF04342.12 KXH62911.1 - 1.1 9.5 8.3 6.4 7.0 1.2 2.7 3 0 0 3 3 3 0 Putative member of DMT superfamily (DUF486) TMEM234 PF10639.9 KXH62911.1 - 8.7 6.4 9.3 2.2 8.4 1.2 2.4 2 0 0 2 2 2 0 Putative transmembrane family 234 FAF PF11250.8 KXH62912.1 - 0.04 14.2 0.0 0.13 12.5 0.0 1.8 2 0 0 2 2 2 0 Fantastic Four meristem regulator Sec63 PF02889.16 KXH62913.1 - 1.1e-07 31.3 0.0 1.4e-07 31.0 0.0 1.1 1 0 0 1 1 1 1 Sec63 Brl domain ACPS PF01648.20 KXH62913.1 - 0.11 12.7 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 4'-phosphopantetheinyl transferase superfamily Peptidase_M4_C PF02868.15 KXH62914.1 - 4e-46 156.9 0.0 1.2e-45 155.4 0.0 1.8 2 0 0 2 2 2 1 Thermolysin metallopeptidase, alpha-helical domain Peptidase_M4 PF01447.18 KXH62914.1 - 3.1e-28 99.1 1.0 4.7e-28 98.5 1.0 1.3 1 0 0 1 1 1 1 Thermolysin metallopeptidase, catalytic domain PLN_propep PF16485.5 KXH62914.1 - 5.1e-21 74.1 1.9 5.4e-13 48.4 0.7 2.4 2 0 0 2 2 2 2 Protealysin propeptide Senescence PF06911.12 KXH62914.1 - 0.017 15.4 0.0 0.074 13.4 0.0 2.0 2 0 0 2 2 2 0 Senescence-associated protein Spermine_synth PF01564.17 KXH62914.1 - 0.056 12.8 0.0 0.13 11.6 0.0 1.5 1 1 1 2 2 2 0 Spermine/spermidine synthase domain Cecropin PF00272.19 KXH62914.1 - 0.11 12.2 0.1 3.7 7.3 0.2 2.8 2 0 0 2 2 2 0 Cecropin family Pec_lyase_C PF00544.19 KXH62915.1 - 8.9e-44 149.6 8.6 1.3e-43 149.0 8.6 1.2 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 KXH62915.1 - 0.00026 20.9 11.9 0.0016 18.3 11.1 2.2 1 1 0 1 1 1 1 Right handed beta helix region MFS_1 PF07690.16 KXH62916.1 - 2.3e-39 135.3 60.6 4.5e-38 131.1 55.5 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1418 PF07214.12 KXH62916.1 - 0.034 14.0 0.1 0.37 10.7 0.0 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1418) Fungal_trans_2 PF11951.8 KXH62917.1 - 8.5e-31 107.1 1.6 1e-30 106.8 1.6 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH62917.1 - 8.7e-06 25.8 8.3 1.4e-05 25.1 8.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RCC1 PF00415.18 KXH62918.1 - 1.3e-52 176.2 13.0 3.2e-10 40.5 0.3 7.2 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KXH62918.1 - 3.4e-32 109.6 38.7 3.7e-07 29.8 1.7 6.6 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat Glyco_hydro_3_C PF01915.22 KXH62920.1 - 1.3e-41 142.8 0.0 2e-41 142.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KXH62920.1 - 8.5e-30 104.2 0.0 1.3e-29 103.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KXH62920.1 - 2.3e-07 30.8 0.0 5e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Band_7 PF01145.25 KXH62923.1 - 1.3e-30 106.7 0.4 2.4e-30 105.9 0.4 1.4 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_C PF16200.5 KXH62923.1 - 2.1e-23 82.1 0.6 6.2e-23 80.6 0.6 1.9 1 0 0 1 1 1 1 C-terminal region of band_7 Pox_A11 PF05061.13 KXH62923.1 - 0.027 13.8 0.2 0.042 13.1 0.2 1.4 1 0 0 1 1 1 0 Poxvirus A11 Protein GSH-S_N PF02951.14 KXH62923.1 - 0.13 12.4 0.1 0.27 11.4 0.1 1.6 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, N-terminal domain UQ_con PF00179.26 KXH62924.1 - 1.8e-16 60.0 0.0 2e-16 59.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KXH62924.1 - 0.002 18.4 0.0 0.0021 18.3 0.0 1.2 1 0 0 1 1 1 1 RWD domain DCB PF16213.5 KXH62925.1 - 8.2e-48 162.4 5.6 1.5e-46 158.3 3.5 2.9 2 0 0 2 2 2 1 Dimerisation and cyclophilin-binding domain of Mon2 Sec7_N PF12783.7 KXH62925.1 - 1.2e-41 142.3 7.9 1.2e-41 142.2 0.0 4.4 6 1 0 6 6 6 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Mon2_C PF16206.5 KXH62925.1 - 4.1e-30 104.6 12.6 5.9e-22 77.7 2.0 4.1 3 1 0 3 3 3 3 C-terminal region of Mon2 protein DUF1981 PF09324.10 KXH62925.1 - 1.9e-07 30.8 0.7 0.00018 21.3 0.0 4.1 4 0 0 4 4 4 1 Domain of unknown function (DUF1981) DUF2398 PF09661.10 KXH62925.1 - 0.2 10.9 4.3 0.86 8.8 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2398) F_actin_bund_C PF18060.1 KXH62925.1 - 0.44 10.7 4.3 0.93 9.7 4.3 1.5 1 0 0 1 1 1 0 F actin bundling C terminal Sugar_tr PF00083.24 KXH62926.1 - 1.4e-80 271.3 20.3 1.7e-80 271.1 20.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH62926.1 - 3.8e-26 91.8 18.9 5.4e-26 91.3 18.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 KXH62926.1 - 7e-05 21.6 0.6 7e-05 21.6 0.6 2.8 3 0 0 3 3 3 2 MFS/sugar transport protein PTR2 PF00854.21 KXH62926.1 - 0.00077 18.4 2.4 0.00077 18.4 2.4 2.0 2 0 0 2 2 2 1 POT family UNC-93 PF05978.16 KXH62926.1 - 0.0059 16.3 2.4 0.0059 16.3 2.4 2.4 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 Dynamin_N PF00350.23 KXH62927.1 - 4.6e-22 78.8 0.0 3.1e-21 76.1 0.0 2.3 1 1 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 KXH62927.1 - 2e-16 60.1 3.2 7.3e-08 32.0 0.3 2.3 2 0 0 2 2 2 2 Dynamin central region GED PF02212.18 KXH62927.1 - 1.3e-05 25.2 0.0 5.5e-05 23.3 0.0 2.0 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KXH62927.1 - 0.00039 20.5 0.0 0.005 16.9 0.0 2.6 2 1 0 2 2 2 1 50S ribosome-binding GTPase Condensin2nSMC PF12422.8 KXH62927.1 - 0.13 12.4 0.9 0.4 10.9 0.2 2.0 2 0 0 2 2 2 0 Condensin II non structural maintenance of chromosomes subunit NTP_transferase PF00483.23 KXH62928.1 - 2.4e-31 109.2 0.0 3e-31 108.9 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 KXH62928.1 - 1.1e-10 40.8 5.4 1.5e-06 27.7 0.0 3.6 3 0 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 KXH62928.1 - 5.4e-06 26.9 0.0 7.9e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain zf-U1 PF06220.12 KXH62932.1 - 4.2e-07 29.6 0.2 6.5e-07 29.0 0.2 1.3 1 0 0 1 1 1 1 U1 zinc finger Zn_clus PF00172.18 KXH62933.1 - 0.015 15.4 8.3 0.025 14.7 8.3 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.24 KXH62934.1 - 7.9e-85 285.4 18.6 9.1e-85 285.2 18.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH62934.1 - 3.1e-18 65.8 23.0 7.9e-17 61.2 17.3 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KXH62934.1 - 9.7e-05 21.1 21.1 0.0077 14.8 6.7 2.9 2 1 1 3 3 3 2 MFS/sugar transport protein Folate_carrier PF01770.18 KXH62934.1 - 0.0001 21.2 0.0 0.0002 20.2 0.0 1.4 1 0 0 1 1 1 1 Reduced folate carrier COX7C PF02935.16 KXH62934.1 - 9.5 6.6 7.9 60 4.0 3.0 2.9 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIIc Alpha-amylase PF00128.24 KXH62935.1 - 9.5e-109 364.0 0.0 1.3e-108 363.5 0.0 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF4434 PF14488.6 KXH62935.1 - 0.02 14.9 0.0 0.036 14.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4434) hDGE_amylase PF14701.6 KXH62935.1 - 0.066 12.3 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain HEAT PF02985.22 KXH62937.1 - 7.2e-14 50.7 1.3 0.0044 17.2 0.1 7.7 7 0 0 7 7 7 2 HEAT repeat HEAT_2 PF13646.6 KXH62937.1 - 1.8e-10 41.1 11.5 0.088 13.2 0.0 7.4 5 1 3 8 8 8 4 HEAT repeats HEAT_EZ PF13513.6 KXH62937.1 - 5.7e-10 39.5 12.2 0.00051 20.5 0.1 7.8 7 1 2 9 9 8 4 HEAT-like repeat Cnd1 PF12717.7 KXH62937.1 - 2.8e-07 30.7 2.8 0.0025 17.9 0.0 3.9 4 1 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 RIX1 PF08167.12 KXH62937.1 - 5.8e-06 26.2 0.0 0.55 9.9 0.0 3.6 3 0 0 3 3 3 2 rRNA processing/ribosome biogenesis IBN_N PF03810.19 KXH62937.1 - 8.1e-06 25.7 1.1 3.8e-05 23.5 0.4 2.6 2 0 0 2 2 2 1 Importin-beta N-terminal domain CLASP_N PF12348.8 KXH62937.1 - 0.00012 21.7 0.0 0.0026 17.4 0.0 3.1 3 0 0 3 3 3 1 CLASP N terminal Adaptin_N PF01602.20 KXH62937.1 - 0.00027 19.6 0.0 0.14 10.7 0.0 2.9 2 0 0 2 2 2 2 Adaptin N terminal region UME PF08064.13 KXH62937.1 - 0.00055 19.8 0.0 0.99 9.4 0.0 4.4 4 0 0 4 4 4 1 UME (NUC010) domain Vac14_Fab1_bd PF12755.7 KXH62937.1 - 0.0014 19.2 0.1 0.93 10.1 0.0 3.9 4 0 0 4 4 3 1 Vacuolar 14 Fab1-binding region Arm PF00514.23 KXH62937.1 - 0.0014 18.6 5.7 4.4 7.5 0.1 6.0 7 0 0 7 7 6 1 Armadillo/beta-catenin-like repeat IFRD PF05004.13 KXH62937.1 - 0.0028 16.8 2.4 2 7.5 0.0 4.2 3 1 2 5 5 5 1 Interferon-related developmental regulator (IFRD) Tti2 PF10521.9 KXH62937.1 - 0.026 14.1 0.1 7.3 6.0 0.0 3.0 2 0 0 2 2 2 0 Tti2 family RTP1_C1 PF10363.9 KXH62937.1 - 0.055 13.7 1.2 1.4 9.1 0.0 3.3 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 Cerato-platanin PF07249.12 KXH62938.1 - 1.2e-59 199.7 4.0 1.3e-59 199.5 4.0 1.0 1 0 0 1 1 1 1 Cerato-platanin GHMP_kinases_N PF00288.26 KXH62939.1 - 1.1e-09 38.4 0.0 2.2e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KXH62939.1 - 0.00018 21.8 0.0 0.00041 20.7 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal PfkB PF00294.24 KXH62940.1 - 3.3e-14 52.9 0.0 5e-14 52.3 0.0 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase WD40 PF00400.32 KXH62942.1 - 6.1e-14 52.2 9.9 0.027 15.3 0.1 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXH62942.1 - 0.00026 21.2 0.0 0.046 14.0 0.0 3.4 2 2 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KXH62942.1 - 0.0033 16.8 0.0 0.0053 16.1 0.0 1.3 1 0 0 1 1 1 1 WD40-like domain FliO PF04347.13 KXH62942.1 - 0.17 12.2 0.0 0.7 10.2 0.0 2.1 1 0 0 1 1 1 0 Flagellar biosynthesis protein, FliO His_Phos_1 PF00300.22 KXH62943.1 - 7.1e-07 29.1 0.0 2.3e-06 27.5 0.0 1.9 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) CTP_transf_like PF01467.26 KXH62944.1 - 4.5e-24 85.3 0.0 2.6e-19 69.8 0.0 3.2 3 0 0 3 3 3 3 Cytidylyltransferase-like FAD_syn PF06574.12 KXH62944.1 - 0.18 11.7 0.3 27 4.6 0.2 3.0 3 0 0 3 3 3 0 FAD synthetase Aminotran_4 PF01063.19 KXH62945.1 - 1.8e-23 83.6 0.0 2.4e-23 83.2 0.0 1.2 1 0 0 1 1 1 1 Amino-transferase class IV Carb_anhydrase PF00194.21 KXH62989.1 - 3.4e-32 112.0 0.0 2.1e-15 57.0 0.0 2.1 2 0 0 2 2 2 2 Eukaryotic-type carbonic anhydrase UPF0164 PF03687.13 KXH62989.1 - 0.031 13.1 0.0 0.043 12.6 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0164) DUF3704 PF12488.8 KXH62990.1 - 0.32 10.7 2.6 1 9.1 2.6 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3704) AAA PF00004.29 KXH62991.1 - 4e-46 156.7 0.0 4.2e-42 143.7 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KXH62991.1 - 5.6e-09 35.7 0.0 3.1e-08 33.3 0.0 2.3 3 0 0 3 3 1 1 AAA+ lid domain AAA_16 PF13191.6 KXH62991.1 - 1.6e-08 35.1 0.1 0.0011 19.4 0.3 3.4 2 1 0 2 2 2 2 AAA ATPase domain IstB_IS21 PF01695.17 KXH62991.1 - 3e-06 27.1 0.0 4.8e-05 23.2 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_2 PF07724.14 KXH62991.1 - 8.1e-06 26.1 0.0 2.3e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KXH62991.1 - 0.00016 21.9 0.1 0.054 13.8 0.2 3.9 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KXH62991.1 - 0.0017 18.3 0.0 0.0079 16.2 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 KXH62991.1 - 0.0071 16.9 0.1 0.048 14.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KXH62991.1 - 0.0096 16.1 5.6 0.029 14.5 0.0 3.8 4 0 0 4 4 4 1 AAA domain RuvB_N PF05496.12 KXH62991.1 - 0.0096 15.7 0.0 0.024 14.4 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 KXH62991.1 - 0.012 16.0 0.0 0.077 13.4 0.0 2.3 2 0 0 2 2 2 0 RNA helicase TIP49 PF06068.13 KXH62991.1 - 0.012 14.8 0.0 0.025 13.8 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_14 PF13173.6 KXH62991.1 - 0.048 13.7 0.0 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KXH62991.1 - 0.06 13.6 0.0 0.18 12.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KXH62991.1 - 0.07 12.5 0.1 0.16 11.3 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Torsin PF06309.11 KXH62991.1 - 0.07 13.2 0.1 2 8.5 0.0 2.3 2 0 0 2 2 2 0 Torsin Parvo_NS1 PF01057.17 KXH62991.1 - 0.12 11.5 0.0 0.22 10.6 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_3 PF07726.11 KXH62991.1 - 0.13 12.1 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 KXH62991.1 - 0.19 11.3 0.0 0.54 9.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region adh_short PF00106.25 KXH62992.1 - 6.9e-34 117.0 0.3 3.5e-24 85.3 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXH62992.1 - 2e-25 89.7 0.3 2.6e-23 82.8 0.3 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH62992.1 - 1.9e-06 27.9 0.0 9.6e-06 25.6 0.0 2.1 3 0 0 3 3 3 1 KR domain DUF1776 PF08643.10 KXH62992.1 - 0.0016 17.9 0.0 0.12 11.7 0.0 2.2 2 1 0 2 2 2 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 KXH62992.1 - 0.0044 16.5 0.0 0.0087 15.5 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Peripla_BP_6 PF13458.6 KXH62992.1 - 0.038 13.7 1.3 0.67 9.5 0.4 2.1 2 0 0 2 2 2 0 Periplasmic binding protein THF_DHG_CYH_C PF02882.19 KXH62992.1 - 0.096 12.0 0.1 0.19 11.0 0.1 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_2 PF03446.15 KXH62992.1 - 0.11 12.6 0.1 0.48 10.6 0.0 1.8 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_10 PF13460.6 KXH62992.1 - 0.13 12.1 1.2 2.1 8.2 1.2 2.3 1 1 0 1 1 1 0 NAD(P)H-binding DSBA PF01323.20 KXH62993.1 - 2.1e-13 50.5 0.0 2e-05 24.5 0.0 2.1 2 0 0 2 2 2 2 DSBA-like thioredoxin domain BCNT PF07572.12 KXH62994.1 - 1.7e-23 82.5 2.5 3.2e-23 81.6 2.5 1.5 1 0 0 1 1 1 1 Bucentaur or craniofacial development WD40 PF00400.32 KXH62996.1 - 2.1e-08 34.7 15.6 0.012 16.5 0.4 5.7 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXH62996.1 - 0.0013 19.0 0.0 1.1 9.6 0.0 4.1 3 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain MraZ PF02381.18 KXH62996.1 - 0.07 13.1 0.0 16 5.6 0.0 2.7 2 0 0 2 2 2 0 MraZ protein, putative antitoxin-like NOA36 PF06524.12 KXH62996.1 - 0.34 10.2 3.0 0.54 9.5 3.0 1.2 1 0 0 1 1 1 0 NOA36 protein Cwf_Cwc_15 PF04889.12 KXH62996.1 - 0.55 9.9 8.3 0.18 11.5 4.8 1.8 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein YL1 PF05764.13 KXH62996.1 - 1.5 8.8 6.2 2.6 8.1 6.2 1.4 1 0 0 1 1 1 0 YL1 nuclear protein SNF2_N PF00176.23 KXH62997.1 - 8.1e-72 241.8 0.8 8.1e-72 241.8 0.8 1.9 3 0 0 3 3 3 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KXH62997.1 - 4.6e-20 72.0 0.1 9.3e-19 67.8 0.0 3.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain Bromodomain PF00439.25 KXH62997.1 - 1.6e-18 66.5 0.1 4.1e-18 65.2 0.1 1.7 1 0 0 1 1 1 1 Bromodomain HSA PF07529.13 KXH62997.1 - 1.1e-16 60.8 13.2 1.1e-16 60.8 13.2 5.1 6 0 0 6 6 6 1 HSA SnAC PF14619.6 KXH62997.1 - 7.6e-14 52.1 0.4 7.6e-14 52.1 0.4 3.8 3 0 0 3 3 3 1 Snf2-ATP coupling, chromatin remodelling complex QLQ PF08880.11 KXH62997.1 - 4.3e-11 42.4 7.8 4.3e-11 42.4 7.8 2.4 2 0 0 2 2 2 1 QLQ ResIII PF04851.15 KXH62997.1 - 9.8e-11 41.9 0.0 9.8e-11 41.9 0.0 3.5 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit RBR PF17208.3 KXH62997.1 - 0.78 10.5 9.8 0.35 11.6 5.3 2.8 1 1 1 2 2 2 0 RNA binding Region HET PF06985.11 KXH62998.1 - 3.7e-22 79.2 0.1 4.3e-20 72.5 0.1 2.5 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MA3 PF02847.17 KXH62999.1 - 4.6e-24 84.6 0.0 1.4e-23 83.0 0.0 1.9 2 0 0 2 2 2 1 MA3 domain MIF4G PF02854.19 KXH62999.1 - 6.9e-08 32.4 0.0 1.4e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 MIF4G domain Cnd1 PF12717.7 KXH62999.1 - 0.069 13.2 0.1 0.15 12.1 0.1 1.5 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 DPM2 PF07297.12 KXH63000.1 - 7.7e-31 106.2 1.4 9.1e-31 106.0 1.4 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.12 KXH63000.1 - 2.2e-05 24.3 0.9 2.6e-05 24.1 0.9 1.1 1 0 0 1 1 1 1 PIG-P DUF4229 PF14012.6 KXH63000.1 - 0.0067 16.5 0.4 0.0067 16.5 0.4 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF4229) LapA_dom PF06305.11 KXH63000.1 - 0.04 13.7 0.5 0.04 13.7 0.5 1.9 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain COX14 PF14880.6 KXH63000.1 - 0.068 13.0 4.8 0.89 9.4 0.0 2.1 2 0 0 2 2 2 0 Cytochrome oxidase c assembly SnoaL_2 PF12680.7 KXH63003.1 - 0.0064 17.1 0.3 0.01 16.5 0.3 1.4 1 1 0 1 1 1 1 SnoaL-like domain SnoaL_4 PF13577.6 KXH63003.1 - 0.02 15.0 3.0 0.052 13.7 3.0 1.7 1 1 0 1 1 1 0 SnoaL-like domain XPG_I PF00867.18 KXH63004.1 - 3.7e-24 84.9 0.0 7e-24 84.0 0.0 1.5 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 KXH63004.1 - 2.5e-05 24.7 0.0 6.3e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain Pneumo_M2 PF07380.11 KXH63004.1 - 0.01 16.1 0.0 0.023 15.0 0.0 1.5 1 0 0 1 1 1 0 Pneumovirus M2 protein XPG_I_2 PF12813.7 KXH63004.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 XPG domain containing AAA PF00004.29 KXH63006.1 - 4.7e-30 104.7 0.0 1.1e-29 103.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KXH63006.1 - 8e-07 28.8 0.0 1.4e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 KXH63006.1 - 0.00014 22.1 0.1 0.11 12.8 0.1 2.3 1 1 1 2 2 2 2 AAA domain AAA_33 PF13671.6 KXH63006.1 - 0.00097 19.3 0.1 0.0028 17.8 0.0 1.9 3 0 0 3 3 2 1 AAA domain DUF815 PF05673.13 KXH63006.1 - 0.0025 17.0 0.0 0.0042 16.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 KXH63006.1 - 0.0046 17.0 0.1 0.012 15.7 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KXH63006.1 - 0.0069 16.8 0.1 0.079 13.3 0.1 2.2 1 1 0 2 2 2 1 AAA ATPase domain RNA_helicase PF00910.22 KXH63006.1 - 0.021 15.2 0.0 0.043 14.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_28 PF13521.6 KXH63006.1 - 0.036 14.3 0.0 0.72 10.1 0.0 2.2 1 1 1 2 2 2 0 AAA domain AAA_14 PF13173.6 KXH63006.1 - 0.036 14.1 0.0 0.078 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 KXH63006.1 - 0.063 13.0 0.0 0.16 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KXH63006.1 - 0.064 12.6 0.0 0.22 10.9 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 KXH63006.1 - 0.13 11.8 0.2 0.43 10.1 0.1 1.8 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KXH63006.1 - 0.14 11.6 0.2 0.44 10.0 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region TniB PF05621.11 KXH63006.1 - 0.17 11.3 0.2 8.5 5.7 0.0 3.0 2 1 1 3 3 3 0 Bacterial TniB protein AAA PF00004.29 KXH63007.1 - 4.4e-28 98.3 0.0 9.2e-13 48.8 0.0 3.6 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KXH63007.1 - 1.4e-10 41.3 0.7 0.011 15.7 0.0 4.3 3 1 0 3 3 3 3 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KXH63007.1 - 3.1e-10 40.0 0.0 0.026 14.3 0.0 4.0 3 1 0 3 3 3 3 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KXH63007.1 - 4.4e-10 40.0 1.9 0.8 10.0 0.5 5.7 4 1 0 4 4 4 2 AAA domain AAA_lid_6 PF17866.1 KXH63007.1 - 5.7e-10 39.2 0.3 1.4e-06 28.3 0.0 3.1 2 0 0 2 2 2 2 AAA lid domain AAA_18 PF13238.6 KXH63007.1 - 6.2e-07 30.0 0.1 0.22 12.1 0.0 4.0 3 0 0 3 3 3 2 AAA domain Mg_chelatase PF01078.21 KXH63007.1 - 1.6e-05 24.4 2.7 1.3 8.4 0.0 3.6 4 0 0 4 4 3 3 Magnesium chelatase, subunit ChlI AAA_30 PF13604.6 KXH63007.1 - 6.5e-05 22.7 1.4 0.48 10.1 0.0 3.7 3 1 0 3 3 3 1 AAA domain TniB PF05621.11 KXH63007.1 - 0.0001 21.8 0.1 0.94 8.9 0.0 3.8 4 1 1 5 5 5 2 Bacterial TniB protein AAA_33 PF13671.6 KXH63007.1 - 0.0001 22.4 0.3 1.1 9.4 0.0 3.6 4 0 0 4 4 3 2 AAA domain AAA_19 PF13245.6 KXH63007.1 - 0.00023 21.5 1.3 0.94 9.8 0.0 3.9 3 1 0 4 4 4 1 AAA domain IstB_IS21 PF01695.17 KXH63007.1 - 0.00045 20.0 0.2 0.2 11.4 0.0 3.1 3 0 0 3 3 3 1 IstB-like ATP binding protein Sigma54_activat PF00158.26 KXH63007.1 - 0.00066 19.4 0.8 1.5 8.5 0.1 4.5 3 2 0 3 3 3 1 Sigma-54 interaction domain AAA_11 PF13086.6 KXH63007.1 - 0.00075 19.4 2.4 1.1 8.9 0.0 3.8 4 0 0 4 4 3 1 AAA domain AAA_16 PF13191.6 KXH63007.1 - 0.00086 19.7 0.4 2.9 8.2 0.0 3.7 3 1 0 3 3 3 1 AAA ATPase domain RNA_helicase PF00910.22 KXH63007.1 - 0.0013 19.1 1.3 3.5 8.1 0.0 4.0 4 0 0 4 4 3 1 RNA helicase Viral_helicase1 PF01443.18 KXH63007.1 - 0.0015 18.3 0.0 0.92 9.2 0.0 2.7 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_24 PF13479.6 KXH63007.1 - 0.0022 17.8 1.9 3.2 7.4 0.0 3.9 4 0 0 4 4 4 1 AAA domain Torsin PF06309.11 KXH63007.1 - 0.0061 16.7 0.0 3.2 7.9 0.0 3.2 3 0 0 3 3 3 1 Torsin AAA_7 PF12775.7 KXH63007.1 - 0.017 14.7 0.4 21 4.6 0.0 3.3 3 0 0 3 3 3 0 P-loop containing dynein motor region Hydin_ADK PF17213.3 KXH63007.1 - 0.033 14.5 0.0 0.033 14.5 0.0 2.6 3 0 0 3 3 2 0 Hydin Adenylate kinase-like domain ResIII PF04851.15 KXH63007.1 - 0.036 14.1 0.0 25 4.8 0.0 3.8 3 1 1 4 4 3 0 Type III restriction enzyme, res subunit AAA_28 PF13521.6 KXH63007.1 - 0.038 14.2 0.3 19 5.5 0.0 3.1 3 0 0 3 3 3 0 AAA domain NTPase_1 PF03266.15 KXH63007.1 - 0.13 12.2 1.7 12 5.7 0.0 3.4 3 0 0 3 3 3 0 NTPase Bactofilin PF04519.13 KXH63008.1 - 0.014 15.7 0.8 0.021 15.1 0.8 1.3 1 0 0 1 1 1 0 Polymer-forming cytoskeletal FapA PF03961.13 KXH63008.1 - 0.031 12.9 0.9 0.041 12.5 0.9 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A MinC_C PF03775.16 KXH63008.1 - 0.1 12.6 0.2 0.17 11.9 0.2 1.5 1 1 0 1 1 1 0 Septum formation inhibitor MinC, C-terminal domain Zn_clus PF00172.18 KXH63010.1 - 9.4e-07 28.9 13.4 1.9e-06 27.8 13.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KXH63010.1 - 0.00016 20.7 2.4 0.00024 20.1 2.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Myb_DNA-bind_3 PF12776.7 KXH63011.1 - 0.11 13.5 0.0 0.19 12.8 0.0 1.3 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Ank_3 PF13606.6 KXH63012.1 - 1.7e-07 30.9 0.2 1.3 9.8 0.0 5.1 5 0 0 5 5 5 3 Ankyrin repeat Ank_2 PF12796.7 KXH63012.1 - 5.2e-05 23.8 0.2 0.95 10.1 0.0 3.6 2 2 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXH63012.1 - 0.00046 20.7 0.5 2.5 8.8 0.1 3.9 3 1 1 4 4 4 3 Ankyrin repeats (many copies) F-box-like PF12937.7 KXH63012.1 - 0.0012 18.7 0.1 0.0039 17.1 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 KXH63012.1 - 0.0039 17.1 0.0 0.0082 16.0 0.0 1.6 1 0 0 1 1 1 1 F-box MFS_1 PF07690.16 KXH63013.1 - 2.1e-29 102.6 51.2 1.6e-18 66.7 36.9 3.4 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.13 KXH63013.1 - 2.2e-09 36.3 29.2 7.4e-08 31.3 29.2 2.8 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Kinocilin PF15033.6 KXH63013.1 - 0.05 13.3 2.5 1.6 8.3 0.5 3.2 2 1 0 2 2 2 0 Kinocilin protein Sulfatase PF00884.23 KXH63016.1 - 0.15 11.5 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 Sulfatase Golgin_A5 PF09787.9 KXH63018.1 - 0.021 14.3 1.7 0.032 13.7 1.7 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF4599 PF15371.6 KXH63018.1 - 0.1 13.2 1.3 0.27 11.8 1.3 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4599) DUF3740 PF12548.8 KXH63018.1 - 0.16 12.4 3.3 0.16 12.4 1.2 2.0 2 0 0 2 2 2 0 Sulfatase protein DUF5082 PF16888.5 KXH63018.1 - 0.27 11.5 3.3 1.1 9.5 3.1 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) DUF4449 PF14613.6 KXH63018.1 - 0.43 10.7 3.6 0.74 9.9 3.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4449) TolA_bind_tri PF16331.5 KXH63018.1 - 0.51 10.5 5.9 5.5 7.1 6.4 2.2 1 1 1 2 2 2 0 TolA binding protein trimerisation Lge1 PF11488.8 KXH63018.1 - 0.74 10.0 4.6 5.4 7.3 0.2 2.3 1 1 1 2 2 2 0 Transcriptional regulatory protein LGE1 DivIC PF04977.15 KXH63018.1 - 5.4 6.9 7.0 11 5.9 7.0 1.5 1 0 0 1 1 1 0 Septum formation initiator Ric8 PF10165.9 KXH63029.1 - 6.3e-128 427.7 0.1 7.5e-128 427.4 0.1 1.1 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn VGPC1_C PF16799.5 KXH63029.1 - 0.047 13.7 0.4 0.13 12.2 0.4 1.8 1 0 0 1 1 1 0 C-terminal membrane-localisation domain of ion-channel, VCN1 Rif1_N PF12231.8 KXH63030.1 - 3.1e-140 467.4 1.5 5.8e-140 466.5 1.5 1.5 1 0 0 1 1 1 1 Rap1-interacting factor 1 N terminal Neurochondrin PF05536.11 KXH63030.1 - 0.028 12.8 0.3 0.061 11.7 0.1 1.6 2 0 0 2 2 2 0 Neurochondrin Aldose_epim PF01263.20 KXH63031.1 - 1.2e-10 41.2 0.0 1.3e-10 41.1 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase SET PF00856.28 KXH63058.1 - 2.5e-08 34.5 0.0 2.7e-07 31.1 0.0 2.3 1 1 0 1 1 1 1 SET domain RGS PF00615.19 KXH63107.1 - 2.7e-10 40.6 0.0 3.5e-10 40.2 0.0 1.1 1 0 0 1 1 1 1 Regulator of G protein signaling domain MAGE_N PF12440.8 KXH63113.1 - 0.2 12.4 6.2 0.3 11.8 6.2 1.3 1 1 0 1 1 1 0 Melanoma associated antigen family N terminal AMP-binding PF00501.28 KXH63114.1 - 6.2e-85 285.3 0.0 7.4e-85 285.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXH63114.1 - 2.2e-18 67.0 0.0 5.2e-18 65.8 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GH3 PF03321.13 KXH63114.1 - 0.00011 21.3 0.0 0.00096 18.1 0.0 2.0 2 0 0 2 2 2 1 GH3 auxin-responsive promoter RTX_C PF08339.10 KXH63114.1 - 0.049 13.7 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 RTX C-terminal domain Methyltr_RsmB-F PF01189.17 KXH63119.1 - 6.4e-32 110.8 0.0 3.9e-25 88.7 0.0 3.1 2 1 0 2 2 2 2 16S rRNA methyltransferase RsmB/F Hamartin PF04388.12 KXH63119.1 - 1.2 7.7 9.9 1.8 7.1 9.9 1.2 1 0 0 1 1 1 0 Hamartin protein RibD_C PF01872.17 KXH63136.1 - 3.6e-36 124.9 0.0 4.2e-36 124.7 0.0 1.0 1 0 0 1 1 1 1 RibD C-terminal domain Transp_cyt_pur PF02133.15 KXH63137.1 - 2.5e-27 95.8 26.2 6.4e-27 94.4 26.2 1.6 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin p450 PF00067.22 KXH63138.1 - 1.8e-60 205.0 0.0 2.3e-60 204.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PfkB PF00294.24 KXH63139.1 - 5e-56 190.2 0.9 5.7e-56 190.0 0.9 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase HemY_N PF07219.13 KXH63140.1 - 0.15 12.2 0.2 0.3 11.3 0.2 1.5 1 0 0 1 1 1 0 HemY protein N-terminus DDDD PF10161.9 KXH63140.1 - 0.22 11.3 3.8 0.36 10.6 0.0 2.7 2 1 1 3 3 3 0 Putative mitochondrial precursor protein Ccdc124 PF06244.12 KXH63142.1 - 1.6e-29 103.0 15.7 1.1e-28 100.3 15.7 2.1 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 124 /Oxs1 MFS_1 PF07690.16 KXH63144.1 - 5.8e-40 137.3 33.4 8.8e-39 133.4 10.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH63144.1 - 5.7e-12 45.2 1.1 5.7e-12 45.2 1.1 2.0 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_3 PF05977.13 KXH63144.1 - 0.035 12.5 2.3 0.14 10.5 2.4 1.8 1 1 0 1 1 1 0 Transmembrane secretion effector Antimicrobial24 PF16049.5 KXH63144.1 - 0.093 12.7 4.8 2.4 8.2 0.3 2.7 2 0 0 2 2 2 0 Frog antimicrobial peptide Fungal_trans PF04082.18 KXH63145.1 - 9.8e-31 106.7 0.0 1.5e-30 106.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH63145.1 - 6.3e-09 35.8 9.5 9.9e-09 35.2 9.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SUIM_assoc PF16619.5 KXH63145.1 - 2.8 8.1 10.0 77 3.5 9.2 2.7 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 CagS PF16707.5 KXH63146.1 - 0.074 13.1 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Cag pathogenicity island protein S of Helicobacter pylori Romo1 PF10247.9 KXH63147.1 - 0.13 12.7 2.6 0.24 11.8 2.4 1.6 1 1 1 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 SGL PF08450.12 KXH63148.1 - 0.00045 19.9 0.0 0.0019 17.8 0.0 2.0 2 1 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region PD40 PF07676.12 KXH63148.1 - 0.024 14.6 0.1 2.8 8.0 0.0 2.6 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Peptidase_M23 PF01551.22 KXH63148.1 - 0.058 13.6 0.1 5.5 7.3 0.0 2.6 2 0 0 2 2 2 0 Peptidase family M23 DUF4805 PF16063.5 KXH63148.1 - 0.072 12.4 0.0 1.8 7.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4805) RCC1_2 PF13540.6 KXH63148.1 - 0.16 11.8 1.0 17 5.4 0.3 2.7 2 0 0 2 2 2 0 Regulator of chromosome condensation (RCC1) repeat GFA PF04828.14 KXH63149.1 - 5.6e-10 39.4 4.0 3.7e-05 24.0 0.0 3.0 3 0 0 3 3 3 2 Glutathione-dependent formaldehyde-activating enzyme Nudix_N_2 PF14803.6 KXH63149.1 - 0.0087 16.0 0.9 7.2 6.6 0.1 3.2 2 0 0 2 2 2 2 Nudix N-terminal Rsm1 PF08600.10 KXH63149.1 - 0.034 14.3 0.1 2.9 8.1 0.0 2.4 2 0 0 2 2 2 0 Rsm1-like zf-NADH-PPase PF09297.11 KXH63149.1 - 0.051 13.3 0.0 0.051 13.3 0.0 2.5 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain zinc_ribbon_2 PF13240.6 KXH63149.1 - 1.2 8.9 9.7 3.7 7.4 0.5 3.2 3 0 0 3 3 3 0 zinc-ribbon domain 2OG-FeII_Oxy_2 PF13532.6 KXH63150.1 - 3.2e-36 125.4 0.0 4.3e-36 124.9 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-GRF PF06839.12 KXH63150.1 - 1.1e-09 38.2 6.8 1.9e-09 37.5 6.8 1.4 1 0 0 1 1 1 1 GRF zinc finger CUE PF02845.16 KXH63150.1 - 0.13 12.0 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 CUE domain MIF4G PF02854.19 KXH63150.1 - 0.17 11.5 0.0 0.26 10.9 0.0 1.2 1 0 0 1 1 1 0 MIF4G domain WD40 PF00400.32 KXH63151.1 - 2.7e-16 59.7 13.3 0.00075 20.3 0.0 6.6 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXH63151.1 - 0.00016 21.9 0.1 0.35 11.2 0.0 3.8 2 2 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 KXH63151.1 - 0.031 14.3 0.0 0.38 10.8 0.0 2.5 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region DEAD PF00270.29 KXH63152.1 - 1.2e-42 145.6 0.0 3.1e-42 144.3 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXH63152.1 - 2.9e-20 72.6 0.1 7.2e-20 71.4 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 KXH63152.1 - 0.00075 18.8 0.0 0.0012 18.1 0.0 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 KXH63152.1 - 0.013 15.5 0.0 0.027 14.5 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_18 PF13238.6 KXH63153.1 - 0.12 12.9 0.2 0.57 10.7 0.2 2.0 1 1 0 1 1 1 0 AAA domain HSP70 PF00012.20 KXH63154.1 - 8e-07 27.6 0.0 8e-07 27.6 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein RNA12 PF10443.9 KXH63155.1 - 3.7e-160 533.5 3.3 5.2e-160 533.0 0.5 1.9 2 0 0 2 2 2 1 RNA12 protein RRM_1 PF00076.22 KXH63155.1 - 1.7e-06 27.8 0.0 7.2e-06 25.7 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ATPase_2 PF01637.18 KXH63155.1 - 0.00031 20.7 1.2 0.037 13.9 0.0 2.7 2 1 0 2 2 2 2 ATPase domain predominantly from Archaea DUF2487 PF10673.9 KXH63155.1 - 0.087 12.8 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2487) LDcluster4 PF18306.1 KXH63155.1 - 0.15 11.6 0.0 0.34 10.5 0.0 1.7 1 0 0 1 1 1 0 SLOG cluster4 family DUF3128 PF11326.8 KXH63156.1 - 1.1e-27 96.1 5.7 2.2e-27 95.2 5.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) Ndc1_Nup PF09531.10 KXH63156.1 - 0.039 12.6 4.5 0.039 12.7 4.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup HSP70 PF00012.20 KXH63157.1 - 3.1e-259 861.2 6.2 3.5e-259 861.0 6.2 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KXH63157.1 - 5.4e-17 61.6 0.1 1.3e-15 57.1 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 KXH63157.1 - 0.0013 18.5 0.0 0.003 17.3 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.18 KXH63157.1 - 0.0092 15.3 0.1 0.024 13.9 0.1 1.7 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase FtsA PF14450.6 KXH63157.1 - 0.012 16.0 0.6 11 6.5 0.0 3.4 3 1 0 3 3 3 0 Cell division protein FtsA BcrAD_BadFG PF01869.20 KXH63157.1 - 0.035 13.6 0.0 2.2 7.7 0.0 2.3 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family FAM91_C PF14648.6 KXH63157.1 - 0.18 10.6 0.2 0.35 9.7 0.2 1.4 1 0 0 1 1 1 0 FAM91 C-terminus Golgin_A5 PF09787.9 KXH63157.1 - 0.48 9.8 8.1 0.47 9.9 5.5 1.9 2 0 0 2 2 2 0 Golgin subfamily A member 5 MutS_III PF05192.18 KXH63157.1 - 2.5 8.3 5.1 9.2 6.4 0.7 2.5 2 1 0 2 2 2 0 MutS domain III RNase_HII PF01351.18 KXH63159.1 - 5.3e-47 160.2 0.0 7.2e-47 159.8 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease HII CENP-C_C PF11699.8 KXH63160.1 - 7.5e-35 119.0 0.3 1.4e-34 118.1 0.3 1.5 1 0 0 1 1 1 1 Mif2/CENP-C like Mif2_N PF15624.6 KXH63160.1 - 1e-33 116.9 5.2 1e-33 116.9 5.2 3.7 3 1 1 4 4 4 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Cupin_2 PF07883.11 KXH63160.1 - 1.4e-07 31.1 0.0 4.3e-07 29.5 0.0 1.8 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 KXH63160.1 - 0.0012 18.5 0.0 0.0037 16.9 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_1 PF00190.22 KXH63160.1 - 0.023 14.3 0.1 0.044 13.4 0.1 1.3 1 0 0 1 1 1 0 Cupin RHD3 PF05879.12 KXH63161.1 - 0 1057.7 0.0 0 1057.4 0.0 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.19 KXH63161.1 - 1.9e-09 37.2 0.4 3.1e-09 36.5 0.4 1.2 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.23 KXH63161.1 - 3.1e-07 30.6 0.1 6e-07 29.7 0.1 1.5 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 KXH63161.1 - 5e-05 23.3 0.0 0.00011 22.3 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_28 PF13521.6 KXH63161.1 - 0.00046 20.5 0.0 0.0017 18.7 0.0 2.0 1 0 0 1 1 1 1 AAA domain Septin PF00735.18 KXH63161.1 - 0.031 13.5 0.1 0.052 12.8 0.1 1.3 1 0 0 1 1 1 0 Septin Fructosamin_kin PF03881.14 KXH63162.1 - 1.9e-72 243.9 0.0 2.2e-72 243.7 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 KXH63162.1 - 0.00089 19.2 0.0 0.0017 18.3 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 KXH63162.1 - 0.057 12.3 0.0 0.083 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) ATP-grasp_2 PF08442.10 KXH63165.1 - 4.4e-76 255.0 0.8 4.4e-76 255.0 0.8 1.7 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.19 KXH63165.1 - 3.7e-27 95.0 0.4 7.8e-27 94.0 0.4 1.6 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 KXH63165.1 - 6.7e-07 29.0 0.1 1.5e-06 27.9 0.1 1.6 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 KXH63165.1 - 0.0016 18.2 1.9 0.035 13.9 0.2 2.6 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain OKR_DC_1_N PF03709.15 KXH63165.1 - 0.12 12.6 0.2 0.7 10.2 0.0 2.4 2 1 0 2 2 2 0 Orn/Lys/Arg decarboxylase, N-terminal domain DUF2721 PF11026.8 KXH63166.1 - 0.093 12.6 0.1 0.23 11.3 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) Neugrin PF06413.11 KXH63167.1 - 1.4e-10 41.6 1.0 1.9e-10 41.2 0.2 1.7 1 1 0 1 1 1 1 Neugrin MRP-L20 PF12824.7 KXH63167.1 - 3.7e-06 27.2 3.5 3.7e-06 27.2 3.5 1.9 2 1 0 2 2 2 1 Mitochondrial ribosomal protein subunit L20 Skp1 PF01466.19 KXH63167.1 - 0.0021 18.1 0.2 0.0021 18.1 0.2 1.8 2 0 0 2 2 2 1 Skp1 family, dimerisation domain DUF5642 PF18702.1 KXH63167.1 - 0.22 11.3 0.0 0.42 10.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5642) DUF2236 PF09995.9 KXH63168.1 - 1.5e-35 123.5 0.4 1.5e-35 123.5 0.4 1.7 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2236) Calcipressin PF04847.12 KXH63169.1 - 1.8e-51 174.6 0.1 2.3e-51 174.2 0.1 1.1 1 0 0 1 1 1 1 Calcipressin MAGI_u5 PF16666.5 KXH63171.1 - 0.016 15.4 2.8 0.084 13.0 0.0 2.2 2 0 0 2 2 2 0 Unstructured region on MAGI tRNA-synt_2d PF01409.20 KXH63172.1 - 4.6e-48 163.8 0.6 7.1e-25 87.9 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 KXH63172.1 - 6e-25 87.5 0.0 1.6e-24 86.1 0.0 1.8 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain Mito_carr PF00153.27 KXH63173.1 - 2.8e-49 165.0 4.0 2.1e-18 66.0 0.2 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KXH63173.1 - 0.11 11.6 0.3 0.31 10.2 0.1 1.8 2 0 0 2 2 2 0 Gammaproteobacterial serine protease RNA_pol_A_bac PF01000.26 KXH63174.1 - 2.1e-33 115.0 0.0 3.4e-33 114.4 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 KXH63174.1 - 7.8e-19 66.9 0.0 1e-18 66.5 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain PriA_CRR PF18319.1 KXH63174.1 - 0.053 13.5 1.7 0.15 12.1 1.7 1.8 1 0 0 1 1 1 0 PriA DNA helicase Cys-rich region (CRR) domain GrpE PF01025.19 KXH63175.1 - 2.2e-49 167.3 5.7 2.8e-49 167.0 5.7 1.1 1 0 0 1 1 1 1 GrpE M-inducer_phosp PF06617.13 KXH63175.1 - 0.0044 16.4 1.1 0.0061 15.9 1.1 1.3 1 0 0 1 1 1 1 M-phase inducer phosphatase DUF334 PF03904.13 KXH63175.1 - 0.031 13.8 0.1 0.045 13.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF334) GPS2_interact PF15784.5 KXH63175.1 - 0.057 13.9 1.3 0.057 13.9 1.3 2.2 2 0 0 2 2 2 0 G-protein pathway suppressor 2-interacting domain APG6_N PF17675.1 KXH63175.1 - 4.4 7.8 11.0 1.5 9.4 7.3 1.8 1 1 1 2 2 2 0 Apg6 coiled-coil region RFC1 PF08519.12 KXH63177.1 - 2e-57 193.8 0.0 4.8e-57 192.5 0.0 1.7 1 0 0 1 1 1 1 Replication factor RFC1 C terminal domain BRCT PF00533.26 KXH63177.1 - 8.6e-15 54.9 0.0 1.9e-14 53.8 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.29 KXH63177.1 - 1.1e-08 35.6 0.1 6.5e-08 33.1 0.1 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 KXH63177.1 - 1.5e-06 28.3 0.0 3.6e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_18 PF13238.6 KXH63177.1 - 0.0015 19.1 0.1 0.008 16.7 0.1 2.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KXH63177.1 - 0.0032 17.7 0.0 0.014 15.7 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KXH63177.1 - 0.0059 17.0 0.1 0.036 14.5 0.1 2.1 1 1 0 2 2 2 1 AAA ATPase domain AAA_28 PF13521.6 KXH63177.1 - 0.011 16.0 0.3 0.17 12.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 KXH63177.1 - 0.035 14.2 0.1 0.13 12.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KXH63177.1 - 0.045 13.9 0.3 0.2 11.8 0.0 2.3 2 0 0 2 2 1 0 AAA domain RuvB_N PF05496.12 KXH63177.1 - 0.091 12.5 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain DNA_pol3_delta PF06144.13 KXH63177.1 - 0.1 12.4 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 DNA polymerase III, delta subunit NTPase_1 PF03266.15 KXH63177.1 - 0.12 12.3 0.0 0.29 11.0 0.0 1.7 1 0 0 1 1 1 0 NTPase PTCB-BRCT PF12738.7 KXH63177.1 - 0.13 12.3 0.0 0.32 11.0 0.0 1.8 1 0 0 1 1 1 0 twin BRCT domain AAA_17 PF13207.6 KXH63177.1 - 2 8.8 7.8 2.1 8.8 0.0 3.6 4 0 0 4 4 4 0 AAA domain Ribosomal_L16 PF00252.18 KXH63178.1 - 3.8e-33 114.3 0.6 5.2e-33 113.9 0.6 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e DNA_pol3_delta2 PF13177.6 KXH63179.1 - 1.3e-10 41.3 0.0 2.8e-10 40.2 0.0 1.6 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA_22 PF13401.6 KXH63179.1 - 8.7e-07 29.3 0.1 1.9e-05 24.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KXH63179.1 - 1.6e-06 28.6 0.1 3.8e-06 27.4 0.1 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KXH63179.1 - 0.00031 21.2 1.2 0.01 16.2 0.4 2.9 2 1 0 2 2 2 1 AAA ATPase domain Rep_fac_C PF08542.11 KXH63179.1 - 0.00065 20.1 0.0 0.002 18.5 0.0 1.8 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA_24 PF13479.6 KXH63179.1 - 0.00068 19.4 0.3 0.002 17.9 0.3 1.7 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 KXH63179.1 - 0.014 15.9 0.0 0.029 14.9 0.0 1.6 1 0 0 1 1 1 0 ABC transporter T4SS-DNA_transf PF02534.14 KXH63179.1 - 0.029 13.2 0.1 0.13 11.0 0.0 1.9 2 0 0 2 2 2 0 Type IV secretory system Conjugative DNA transfer Rad17 PF03215.15 KXH63179.1 - 0.034 14.1 0.0 0.059 13.3 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_5 PF07728.14 KXH63179.1 - 0.18 11.8 0.5 0.59 10.1 0.4 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.6 KXH63179.1 - 0.21 11.4 0.1 4.6 7.1 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain AMP-binding PF00501.28 KXH63180.1 - 5.8e-86 288.7 0.1 7.1e-86 288.4 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXH63180.1 - 1.3e-26 93.3 0.7 3e-25 89.0 0.5 2.5 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 KXH63180.1 - 1.5e-19 69.6 0.4 4.5e-19 68.1 0.4 1.9 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus Reprolysin_5 PF13688.6 KXH63181.1 - 1.2e-61 208.3 9.2 1.2e-61 208.3 9.2 3.0 2 1 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 KXH63181.1 - 2.1e-53 181.1 3.9 2.1e-53 181.1 3.9 2.0 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KXH63181.1 - 3.7e-49 167.1 5.0 6.5e-49 166.3 5.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.23 KXH63181.1 - 4.8e-17 62.5 32.6 4.8e-17 62.5 32.6 4.7 3 1 0 3 3 3 1 Disintegrin Reprolysin_3 PF13582.6 KXH63181.1 - 2.2e-13 50.8 0.1 5.8e-13 49.4 0.1 1.8 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin PF01421.19 KXH63181.1 - 8.6e-05 22.5 8.4 8.6e-05 22.5 8.4 3.2 2 1 0 2 2 2 1 Reprolysin (M12B) family zinc metalloprotease ADAM_CR_2 PF17771.1 KXH63181.1 - 0.00047 20.6 14.4 0.00047 20.6 14.4 5.2 2 1 2 4 4 4 1 ADAM cysteine-rich domain Pep_M12B_propep PF01562.19 KXH63181.1 - 0.013 15.7 0.2 0.028 14.6 0.2 1.5 1 0 0 1 1 1 0 Reprolysin family propeptide DUF4953 PF16313.5 KXH63181.1 - 0.24 10.6 0.0 0.4 9.8 0.0 1.3 1 0 0 1 1 1 0 Met-zincin WD40 PF00400.32 KXH63183.1 - 2.8e-07 31.1 3.6 0.46 11.4 0.0 6.0 6 0 0 6 6 6 2 WD domain, G-beta repeat LisH PF08513.11 KXH63183.1 - 6.4e-07 29.1 0.1 1.5e-06 28.0 0.1 1.6 1 0 0 1 1 1 1 LisH ANAPC4_WD40 PF12894.7 KXH63183.1 - 6.2e-06 26.4 0.2 0.079 13.3 0.0 4.7 3 3 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KXH63183.1 - 0.17 11.9 0.5 19 5.3 0.0 3.3 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat IKI3 PF04762.12 KXH63183.1 - 0.28 9.1 0.0 0.61 8.0 0.0 1.5 1 0 0 1 1 1 0 IKI3 family Epimerase PF01370.21 KXH63185.1 - 1.2e-13 51.2 0.0 2.1e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KXH63185.1 - 2.4e-10 40.6 0.0 4e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KXH63185.1 - 5.3e-09 35.9 0.0 8.6e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KXH63185.1 - 1.3e-08 34.2 0.0 1.8e-08 33.7 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KXH63185.1 - 4e-06 26.2 0.0 0.00064 19.0 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein NmrA PF05368.13 KXH63185.1 - 0.00012 21.8 0.0 0.00022 20.9 0.0 1.5 1 1 0 1 1 1 1 NmrA-like family adh_short PF00106.25 KXH63185.1 - 0.022 14.2 0.5 0.038 13.4 0.0 1.7 2 1 0 2 2 2 0 short chain dehydrogenase Polysacc_synt_2 PF02719.15 KXH63185.1 - 0.056 12.6 0.0 0.076 12.1 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Sel1 PF08238.12 KXH63186.1 - 3.8e-16 59.2 28.2 1e-06 29.2 0.2 7.8 7 0 0 7 7 7 5 Sel1 repeat TPR_1 PF00515.28 KXH63186.1 - 0.00053 19.7 1.1 0.0019 18.0 0.2 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 KXH63186.1 - 5.6 7.4 8.8 1.5 9.2 0.2 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat ECH_1 PF00378.20 KXH63198.1 - 8.6e-36 123.5 0.0 1e-35 123.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXH63198.1 - 1.2e-16 61.2 0.0 1.6e-16 60.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase LppA PF16708.5 KXH63198.1 - 0.027 14.4 0.0 0.048 13.6 0.0 1.3 1 0 0 1 1 1 0 Lipoprotein confined to pathogenic Mycobacterium SPRY PF00622.28 KXH63199.1 - 2.4e-07 30.9 0.2 1.1e-06 28.8 0.0 2.1 3 0 0 3 3 3 1 SPRY domain Na_Ca_ex PF01699.24 KXH63200.1 - 3.9e-41 140.5 38.5 1.5e-21 77.0 18.7 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Pkinase PF00069.25 KXH63201.1 - 9.4e-65 218.6 0.0 1.9e-64 217.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXH63201.1 - 7e-37 127.1 0.0 4.9e-31 107.9 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KXH63201.1 - 3.5e-07 29.8 0.0 3.2e-05 23.4 0.0 2.2 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 KXH63201.1 - 0.00024 21.1 0.0 0.00052 20.0 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KXH63201.1 - 0.016 14.2 0.2 0.026 13.5 0.2 1.3 1 0 0 1 1 1 0 Haspin like kinase domain RIO1 PF01163.22 KXH63201.1 - 0.02 14.5 0.0 0.041 13.5 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 KXH63201.1 - 0.029 13.7 0.0 0.055 12.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family GWT1 PF06423.12 KXH63202.1 - 9.8e-44 149.1 2.4 9.8e-44 149.1 2.4 1.9 2 0 0 2 2 2 1 GWT1 DUF4818 PF16089.5 KXH63202.1 - 0.00017 22.0 0.9 0.00076 19.9 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4818) PDZ_assoc PF10600.9 KXH63203.1 - 0.13 13.1 2.2 0.45 11.4 0.3 2.1 2 0 0 2 2 2 0 PDZ-associated domain of NMDA receptors COX16 PF14138.6 KXH63203.1 - 0.13 12.8 0.0 0.17 12.4 0.0 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein COX16 Glyco_tranf_2_3 PF13641.6 KXH63205.1 - 4.3e-22 79.1 0.0 5.7e-22 78.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 KXH63205.1 - 6.4e-06 25.8 0.0 1.6e-05 24.5 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 KXH63205.1 - 0.00017 21.5 0.0 0.00054 19.8 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 2 ALMT PF11744.8 KXH63206.1 - 8.9 5.0 8.6 12 4.6 8.6 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Amidase PF01425.21 KXH63207.1 - 2.5e-12 46.5 0.0 4.3e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 Amidase CobW_C PF07683.14 KXH63208.1 - 0.092 12.7 0.0 0.26 11.2 0.0 1.8 1 0 0 1 1 1 0 Cobalamin synthesis protein cobW C-terminal domain RskA PF10099.9 KXH63224.1 - 0.0077 16.5 2.4 0.0089 16.3 2.4 1.0 1 0 0 1 1 1 1 Anti-sigma-K factor rskA HpcH_HpaI PF03328.14 KXH63227.1 - 4.4e-46 156.8 0.0 7.9e-46 155.9 0.0 1.4 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 KXH63227.1 - 4.8e-13 49.0 0.1 3.4e-06 26.5 0.0 2.1 2 0 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold PK PF00224.21 KXH63227.1 - 0.0048 15.8 0.0 0.0067 15.4 0.0 1.2 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain Malate_synthase PF01274.22 KXH63227.1 - 0.075 11.3 0.0 7.9 4.6 0.0 2.7 3 0 0 3 3 3 0 Malate synthase PEPcase_2 PF14010.6 KXH63227.1 - 0.17 10.3 0.0 0.3 9.6 0.0 1.3 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxylase DUF846 PF05832.12 KXH63228.1 - 8.3e-46 155.5 14.7 1.7e-42 144.8 7.2 2.1 2 0 0 2 2 2 2 Eukaryotic protein of unknown function (DUF846) Phage_holin_5_1 PF06946.11 KXH63228.1 - 0.31 11.4 1.6 0.67 10.4 0.8 2.0 2 0 0 2 2 2 0 Bacteriophage A118-like holin, Hol118 Promethin PF16015.5 KXH63228.1 - 1.4 8.8 15.5 6.3 6.8 0.2 3.1 3 0 0 3 3 3 0 Promethin Pkinase PF00069.25 KXH63229.1 - 5.3e-61 206.3 0.0 1.6e-60 204.7 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXH63229.1 - 1.3e-27 96.7 0.0 2.7e-27 95.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 KXH63229.1 - 1.1e-10 41.7 0.0 1.6e-08 34.7 0.0 2.8 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 KXH63229.1 - 0.00098 19.4 0.0 0.0035 17.6 0.0 1.9 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Kinase-like PF14531.6 KXH63229.1 - 0.042 13.2 0.0 0.1 11.9 0.0 1.5 1 1 0 1 1 1 0 Kinase-like Kdo PF06293.14 KXH63229.1 - 0.1 11.9 0.1 0.18 11.1 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KXH63229.1 - 0.13 11.0 0.0 0.29 9.8 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 KXH63229.1 - 0.41 10.5 2.0 2.2 8.1 0.3 2.5 2 1 1 3 3 3 0 Phosphotransferase enzyme family PH PF00169.29 KXH63230.1 - 2.1e-07 31.4 0.1 4.8e-06 27.0 0.0 2.5 2 0 0 2 2 2 1 PH domain PH_9 PF15410.6 KXH63230.1 - 0.0052 17.1 0.0 0.017 15.5 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain DUF4055 PF13264.6 KXH63230.1 - 2.5 8.3 10.7 5.5 7.2 10.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4055) PP2C PF00481.21 KXH63233.1 - 0.00011 22.0 0.0 0.014 15.1 0.0 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.12 KXH63233.1 - 0.0076 16.2 0.0 0.022 14.6 0.0 1.9 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) APOC4 PF15119.6 KXH63233.1 - 0.15 12.3 0.3 0.5 10.7 0.1 1.9 2 0 0 2 2 2 0 Apolipoprotein C4 Fcf1 PF04900.12 KXH63234.1 - 3.1e-30 104.5 0.2 5.1e-30 103.8 0.2 1.4 1 0 0 1 1 1 1 Fcf1 DUF726 PF05277.12 KXH63235.1 - 9.1e-127 422.7 0.4 1.3e-126 422.2 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Podoplanin PF05808.11 KXH63236.1 - 3.1e-05 24.1 0.4 3.1e-05 24.1 0.4 2.9 3 1 1 4 4 4 1 Podoplanin VSP PF03302.13 KXH63236.1 - 0.00043 19.3 0.2 0.00067 18.6 0.2 1.3 1 0 0 1 1 1 1 Giardia variant-specific surface protein Yip1 PF04893.17 KXH63236.1 - 0.0075 16.0 0.1 0.014 15.1 0.1 1.4 1 0 0 1 1 1 1 Yip1 domain Adeno_E3_CR2 PF02439.15 KXH63236.1 - 0.0093 15.7 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Zip PF02535.22 KXH63236.1 - 0.015 14.5 1.1 0.027 13.7 1.1 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Syndecan PF01034.20 KXH63236.1 - 0.047 13.6 0.0 0.086 12.8 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain EphA2_TM PF14575.6 KXH63236.1 - 0.15 13.0 0.0 0.39 11.6 0.0 1.8 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain STT3 PF02516.14 KXH63238.1 - 3.6e-144 481.3 35.1 2.6e-139 465.3 32.7 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit ATP-synt_E PF05680.12 KXH63239.1 - 1.5e-24 86.2 0.1 1.6e-24 86.1 0.1 1.0 1 0 0 1 1 1 1 ATP synthase E chain Drf_GBD PF06371.13 KXH63239.1 - 0.054 13.1 0.0 0.056 13.0 0.0 1.1 1 0 0 1 1 1 0 Diaphanous GTPase-binding Domain WD40 PF00400.32 KXH63240.1 - 1.9e-06 28.5 8.4 0.37 11.7 0.9 5.7 6 1 0 6 6 6 3 WD domain, G-beta repeat Aldo_ket_red PF00248.21 KXH63241.1 - 2.6e-62 210.7 0.0 3e-62 210.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family zf-CCCH_4 PF18044.1 KXH63242.1 - 0.00036 20.3 3.9 0.00053 19.7 3.9 1.3 1 0 0 1 1 1 1 CCCH-type zinc finger Torus PF16131.5 KXH63242.1 - 0.00061 20.5 0.3 0.0014 19.3 0.3 1.6 1 0 0 1 1 1 1 Torus domain zf-CCCH PF00642.24 KXH63242.1 - 0.0074 16.2 3.2 0.011 15.6 3.2 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF3135 PF11333.8 KXH63242.1 - 0.13 12.5 0.0 0.25 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3135) zf_CCCH_4 PF18345.1 KXH63242.1 - 0.14 12.3 9.2 0.2 11.7 9.2 1.3 1 0 0 1 1 1 0 Zinc finger domain CAP_GLY PF01302.25 KXH63243.1 - 6.4e-18 64.5 0.0 1.1e-17 63.8 0.0 1.4 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.7 KXH63243.1 - 1.7e-12 47.4 1.4 0.0014 18.9 0.1 4.5 2 1 3 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXH63243.1 - 1.9e-11 43.5 9.3 4.1e-05 23.3 3.5 4.4 4 2 0 4 4 4 2 Leucine rich repeat LRR_6 PF13516.6 KXH63243.1 - 6.8e-07 28.8 1.4 3.7 7.8 0.0 5.9 6 0 0 6 6 6 3 Leucine Rich repeat LRR_9 PF14580.6 KXH63243.1 - 2.9e-05 23.6 0.0 0.11 12.0 0.0 3.2 1 1 2 3 3 3 3 Leucine-rich repeat LRR_1 PF00560.33 KXH63243.1 - 0.013 16.0 5.6 96 4.2 0.0 5.9 6 1 0 6 6 6 0 Leucine Rich Repeat MaoC_dehydratas PF01575.19 KXH63244.1 - 5.4e-22 77.7 0.0 9.2e-22 76.9 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 KXH63244.1 - 0.00021 21.4 0.0 0.035 14.3 0.0 2.7 2 1 0 2 2 2 2 N-terminal half of MaoC dehydratase PI-PLC-X PF00388.19 KXH63247.1 - 7.6e-09 35.3 0.0 1.2e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain TOH_N PF12549.8 KXH63251.1 - 0.014 15.2 3.3 0.035 13.9 3.3 1.7 1 0 0 1 1 1 0 Tyrosine hydroxylase N terminal S-AdoMet_synt_C PF02773.16 KXH63252.1 - 2.5e-65 218.7 0.6 5.4e-65 217.5 0.0 1.8 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 KXH63252.1 - 1.2e-45 154.6 0.0 2.4e-45 153.7 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 KXH63252.1 - 4.6e-43 145.9 0.4 1.1e-42 144.7 0.0 1.8 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain AdoMet_Synthase PF01941.19 KXH63252.1 - 0.096 11.5 0.4 0.65 8.7 0.1 2.0 1 1 0 2 2 2 0 S-adenosylmethionine synthetase (AdoMet synthetase) ATP_bind_1 PF03029.17 KXH63253.1 - 1.9e-71 240.7 0.0 2.6e-71 240.3 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_24 PF13479.6 KXH63253.1 - 0.0005 19.9 0.0 0.00081 19.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain CLP1_P PF16575.5 KXH63253.1 - 0.00053 19.8 0.0 0.0012 18.7 0.0 1.5 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_14 PF13173.6 KXH63253.1 - 0.00076 19.5 0.0 0.0019 18.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 KXH63253.1 - 0.0038 17.6 0.0 0.0089 16.4 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_18 PF13238.6 KXH63253.1 - 0.0043 17.6 0.0 0.01 16.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain CbiA PF01656.23 KXH63253.1 - 0.0097 16.0 0.0 0.011 15.8 0.0 1.3 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain RsgA_GTPase PF03193.16 KXH63253.1 - 0.013 15.4 0.1 0.46 10.4 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase GTP_EFTU PF00009.27 KXH63253.1 - 0.015 14.9 0.0 3.6 7.1 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 KXH63253.1 - 0.015 15.6 0.0 0.031 14.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KXH63253.1 - 0.018 15.2 0.0 0.027 14.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KXH63253.1 - 0.048 13.2 0.0 0.088 12.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 KXH63253.1 - 0.076 13.4 0.0 0.25 11.7 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.27 KXH63253.1 - 0.078 13.5 0.0 0.16 12.5 0.0 1.5 1 0 0 1 1 1 0 ABC transporter SRP54 PF00448.22 KXH63253.1 - 0.078 12.6 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain PPV_E1_C PF00519.17 KXH63253.1 - 0.092 11.6 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase Cytidylate_kin PF02224.18 KXH63253.1 - 0.1 12.3 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Cytidylate kinase AAA_29 PF13555.6 KXH63253.1 - 0.11 12.3 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Septin PF00735.18 KXH63253.1 - 0.11 11.8 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Septin KAP_NTPase PF07693.14 KXH63253.1 - 0.11 11.7 0.0 0.2 10.9 0.0 1.3 1 1 0 1 1 1 0 KAP family P-loop domain NACHT PF05729.12 KXH63253.1 - 0.13 12.2 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 NACHT domain MMR_HSR1 PF01926.23 KXH63253.1 - 0.14 12.3 0.0 0.41 10.7 0.0 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase cobW PF02492.19 KXH63253.1 - 0.15 11.6 0.1 7.1 6.2 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 KXH63253.1 - 0.15 11.8 0.0 1.7 8.4 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_25 PF13481.6 KXH63253.1 - 0.17 11.4 0.0 1.1 8.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain Apq12 PF12716.7 KXH63254.1 - 4.4e-16 58.6 14.1 7.8e-16 57.8 14.1 1.4 1 0 0 1 1 1 1 Nuclear pore assembly and biogenesis Antimicrobial_7 PF08102.11 KXH63254.1 - 0.0019 18.4 0.3 0.14 12.4 0.0 2.6 3 0 0 3 3 3 1 Scorpion antimicrobial peptide YqjK PF13997.6 KXH63254.1 - 2.6 8.4 8.0 1 9.6 1.5 2.5 2 1 1 3 3 3 0 YqjK-like protein THF_DHG_CYH PF00763.23 KXH63256.1 - 1.5e-22 80.0 0.1 2.9e-22 79.1 0.1 1.5 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.19 KXH63256.1 - 4.7e-15 55.3 0.0 1.1e-08 34.6 0.0 2.4 2 0 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain MMS19_N PF14500.6 KXH63257.1 - 2.5e-53 181.3 0.0 6.3e-53 180.0 0.0 1.7 1 0 0 1 1 1 1 Dos2-interacting transcription regulator of RNA-Pol-II SPC25 PF06703.11 KXH63258.1 - 3e-54 183.2 0.2 3.5e-54 183.0 0.2 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) EMC3_TMCO1 PF01956.16 KXH63259.1 - 2.2e-52 177.2 0.8 2.7e-52 176.9 0.8 1.1 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like RNA_pol_Rbc25 PF08292.12 KXH63260.1 - 3.1e-32 111.5 1.7 2.1e-31 108.9 1.7 2.0 1 1 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 KXH63260.1 - 7.9e-15 55.0 0.0 1.2e-14 54.4 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 NUFIP1 PF10453.9 KXH63261.1 - 4.5e-07 29.6 1.2 8.8e-07 28.7 0.0 2.1 2 0 0 2 2 2 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf_CCCH_4 PF18345.1 KXH63261.1 - 0.038 14.1 6.8 0.072 13.2 6.8 1.5 1 0 0 1 1 1 0 Zinc finger domain zf-CCCH PF00642.24 KXH63261.1 - 0.19 11.7 5.9 0.44 10.5 5.9 1.6 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) MCM3AP_GANP PF16769.5 KXH63261.1 - 0.75 8.0 4.4 1.1 7.4 4.4 1.1 1 0 0 1 1 1 0 MCM3AP domain of GANP DUF4358 PF14270.6 KXH63261.1 - 0.82 10.0 2.1 1.5 9.2 2.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4358) DUF3295 PF11702.8 KXH63263.1 - 1.9e-167 558.6 28.1 2.3e-167 558.3 28.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3295) DUF1752 PF08550.10 KXH63263.1 - 1.2e-12 47.4 2.0 2.5e-12 46.4 2.0 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) SUR7 PF06687.12 KXH63266.1 - 1.8e-25 89.9 8.3 2.4e-25 89.4 8.3 1.1 1 0 0 1 1 1 1 SUR7/PalI family 7TM_GPCR_Srd PF10317.9 KXH63266.1 - 0.85 8.7 7.3 0.84 8.8 6.3 1.4 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srd ABC1 PF03109.16 KXH63267.1 - 5.8e-22 78.1 0.0 1.4e-21 76.9 0.0 1.6 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 KXH63267.1 - 2.2e-05 24.5 0.0 5.4e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family K_oxygenase PF13434.6 KXH63268.1 - 3.5e-109 365.1 0.0 9.3e-109 363.7 0.0 1.6 1 1 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KXH63268.1 - 5.3e-07 29.2 0.0 3.7e-06 26.4 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXH63268.1 - 2.4e-06 27.0 0.0 5.3e-05 22.6 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXH63268.1 - 3.7e-06 27.0 0.1 0.0068 16.4 0.0 2.6 2 1 0 2 2 2 2 FAD-NAD(P)-binding Fungal_trans PF04082.18 KXH63269.1 - 1.7e-14 53.5 0.0 3.4e-14 52.5 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH63269.1 - 2.2e-06 27.7 11.4 4.1e-06 26.8 11.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain IF-2B PF01008.17 KXH63270.1 - 1.3e-22 80.3 0.0 1.8e-22 79.9 0.0 1.2 1 0 0 1 1 1 1 Initiation factor 2 subunit family NUDIX PF00293.28 KXH63270.1 - 1.4e-12 47.7 0.1 3.1e-12 46.7 0.1 1.5 1 0 0 1 1 1 1 NUDIX domain Acyl-CoA_dh_2 PF08028.11 KXH63270.1 - 0.09 13.1 0.0 1.1 9.6 0.0 2.5 3 0 0 3 3 3 0 Acyl-CoA dehydrogenase, C-terminal domain MFS_1 PF07690.16 KXH63271.1 - 3.4e-30 105.1 22.9 3.4e-30 105.1 22.9 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily ESSS PF10183.9 KXH63271.1 - 0.32 11.2 0.8 2.3 8.4 0.1 2.5 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) CD20 PF04103.15 KXH63271.1 - 7.6 6.6 9.7 0.2 11.8 1.4 2.4 2 0 0 2 2 2 0 CD20-like family Cytochrom_B561 PF03188.16 KXH63272.1 - 3.3e-05 24.0 9.8 3.3e-05 24.0 9.8 1.9 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 DUF4079 PF13301.6 KXH63272.1 - 0.0016 18.6 4.9 0.0016 18.6 4.9 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF4079) DUF2306 PF10067.9 KXH63272.1 - 0.021 15.0 1.0 0.021 15.0 1.0 2.3 1 1 2 3 3 3 0 Predicted membrane protein (DUF2306) Saf_2TM PF18303.1 KXH63272.1 - 0.026 14.1 0.0 0.026 14.1 0.0 2.7 1 1 2 3 3 3 0 SAVED-fused 2TM effector domain MWFE PF15879.5 KXH63272.1 - 5.3 7.3 0.0 5.3 7.3 0.0 3.2 4 0 0 4 4 4 0 NADH-ubiquinone oxidoreductase MWFE subunit DUF5592 PF17332.2 KXH63272.1 - 6.4 7.4 6.5 11 6.7 0.1 2.7 2 1 1 3 3 3 0 Family of unknown function (DUF5592) FF PF01846.19 KXH63273.1 - 1.1e-10 41.5 5.6 2.9e-09 37.0 0.5 3.2 3 0 0 3 3 3 2 FF domain WW PF00397.26 KXH63273.1 - 2.1e-08 34.1 2.1 2.1e-08 34.1 2.1 2.8 3 0 0 3 3 3 1 WW domain DUF5641 PF18701.1 KXH63273.1 - 1.2 9.3 4.4 0.84 9.8 1.6 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5641) PAP2 PF01569.21 KXH63274.1 - 2.4e-27 95.3 0.9 2.4e-27 95.3 0.9 2.2 2 0 0 2 2 2 1 PAP2 superfamily TM140 PF14985.6 KXH63274.1 - 0.044 13.3 0.2 0.13 11.7 0.0 1.8 2 0 0 2 2 2 0 TM140 protein family HisKA_7TM PF16927.5 KXH63274.1 - 0.11 12.6 11.0 0.12 12.4 6.2 2.4 1 1 0 2 2 2 0 N-terminal 7TM region of histidine kinase PAP2_3 PF14378.6 KXH63274.1 - 1.8 8.2 10.7 15 5.2 9.5 2.6 1 1 0 1 1 1 0 PAP2 superfamily Proteasome PF00227.26 KXH63275.1 - 1.3e-60 204.2 0.1 1.6e-60 203.8 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KXH63275.1 - 2.8e-13 49.3 0.1 8.7e-13 47.7 0.1 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DUF5624 PF18538.1 KXH63275.1 - 0.011 15.9 0.7 0.035 14.2 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5624) Nitrate_red_gam PF02665.14 KXH63275.1 - 0.022 14.3 0.0 0.032 13.8 0.0 1.2 1 0 0 1 1 1 0 Nitrate reductase gamma subunit SPOC PF07744.13 KXH63276.1 - 3.2e-26 92.1 0.0 5e-26 91.4 0.0 1.3 1 0 0 1 1 1 1 SPOC domain TFIIS_M PF07500.14 KXH63276.1 - 8.8e-15 55.2 1.6 8.8e-15 55.2 1.6 1.8 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain PHD PF00628.29 KXH63276.1 - 4.6e-09 36.0 8.5 8.8e-09 35.1 8.5 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 KXH63276.1 - 0.66 9.6 3.2 1.1 8.8 3.2 1.4 1 0 0 1 1 1 0 PHD-finger CDC45 PF02724.14 KXH63276.1 - 0.87 7.8 9.5 1.5 7.0 9.5 1.4 1 0 0 1 1 1 0 CDC45-like protein FXMRP1_C_core PF12235.8 KXH63276.1 - 9.9 6.8 21.6 4.1 8.1 1.3 2.6 2 0 0 2 2 2 0 Fragile X-related 1 protein core C terminal Med7 PF05983.11 KXH63277.1 - 2.6e-59 200.5 0.1 3.1e-59 200.3 0.1 1.1 1 0 0 1 1 1 1 MED7 protein TBCC_N PF16752.5 KXH63277.1 - 0.084 13.3 0.0 0.53 10.7 0.0 2.2 2 0 0 2 2 2 0 Tubulin-specific chaperone C N-terminal domain zf-C2H2_jaz PF12171.8 KXH63278.1 - 0.007 16.6 0.1 0.013 15.7 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding DUF1677 PF07911.13 KXH63278.1 - 0.17 12.3 0.1 0.17 12.3 0.1 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1677) zf-met PF12874.7 KXH63278.1 - 0.18 12.3 0.1 0.29 11.6 0.1 1.3 1 0 0 1 1 1 0 Zinc-finger of C2H2 type AbiH PF14253.6 KXH63278.1 - 0.19 11.6 0.3 0.26 11.1 0.3 1.2 1 0 0 1 1 1 0 Bacteriophage abortive infection AbiH LAMTOR PF15454.6 KXH63280.1 - 1e-11 45.3 0.1 1.6e-11 44.6 0.1 1.3 1 0 0 1 1 1 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator Exo_endo_phos_2 PF14529.6 KXH63282.1 - 2.3e-05 24.2 0.0 5.8e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Cas_GSU0053 PF09617.10 KXH63284.1 - 0.016 15.1 0.0 0.04 13.9 0.0 1.6 1 0 0 1 1 1 0 CRISPR-associated protein GSU0053 (Cas_GSU0053) Med8 PF10232.9 KXH63285.1 - 3e-34 118.6 0.0 3.8e-34 118.3 0.0 1.1 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 GEN1_C PF18380.1 KXH63285.1 - 0.049 14.5 0.5 0.084 13.8 0.5 1.4 1 0 0 1 1 1 0 Holliday junction resolvase Gen1 C-terminal domain NOA36 PF06524.12 KXH63285.1 - 1.6 8.0 4.9 2.2 7.5 4.9 1.1 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.12 KXH63285.1 - 6.4 4.8 6.7 4.5 5.4 4.5 1.7 2 0 0 2 2 2 0 Nop14-like family Sulfatase PF00884.23 KXH63286.1 - 8.9e-57 192.8 0.0 1.1e-56 192.5 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Choline_sulf_C PF12411.8 KXH63286.1 - 2.9e-26 91.0 1.6 2.9e-26 91.0 1.6 2.6 3 0 0 3 3 3 1 Choline sulfatase enzyme C terminal Phosphodiest PF01663.22 KXH63286.1 - 2.8e-09 37.0 0.0 0.0013 18.4 0.0 2.3 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4976 PF16347.5 KXH63286.1 - 0.0019 18.4 0.0 0.0037 17.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4976) DUF229 PF02995.17 KXH63286.1 - 0.096 11.3 0.0 0.13 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) DUF4994 PF16385.5 KXH63286.1 - 0.14 12.1 0.0 16 5.5 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function RasGAP PF00616.19 KXH63287.1 - 6e-52 176.4 0.0 1.5e-51 175.1 0.0 1.7 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 KXH63287.1 - 3.3e-49 166.5 3.2 3.3e-49 166.5 3.2 2.3 2 0 0 2 2 2 1 RasGAP C-terminus IQ PF00612.27 KXH63287.1 - 2.6e-19 67.1 29.6 0.0018 17.9 0.1 14.2 15 0 0 15 15 15 5 IQ calmodulin-binding motif CH PF00307.31 KXH63287.1 - 6.1e-11 42.5 0.0 2.1e-10 40.7 0.0 1.9 1 0 0 1 1 1 1 Calponin homology (CH) domain DUF2067 PF09840.9 KXH63287.1 - 0.03 13.9 0.3 0.13 11.8 0.3 2.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2067) Trimer_CC PF08954.11 KXH63287.1 - 0.27 10.8 4.7 0.15 11.6 0.4 3.0 3 0 0 3 3 3 0 Trimerisation motif Spc7 PF08317.11 KXH63287.1 - 0.53 9.1 21.0 0.1 11.5 5.1 3.3 3 0 0 3 3 3 0 Spc7 kinetochore protein Sipho_Gp157 PF05565.11 KXH63287.1 - 2.5 8.1 7.6 0.52 10.3 1.2 2.8 2 0 0 2 2 2 0 Siphovirus Gp157 DUF29 PF01724.16 KXH63287.1 - 2.5 8.3 6.9 2 8.6 0.2 3.0 2 0 0 2 2 2 0 Domain of unknown function DUF29 IMPDH PF00478.25 KXH63288.1 - 8.9e-127 422.8 2.8 1e-126 422.6 2.8 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 KXH63288.1 - 6.3e-16 58.6 0.1 1.2e-07 32.0 0.1 2.5 2 0 0 2 2 2 2 CBS domain FMN_dh PF01070.18 KXH63288.1 - 4.1e-09 35.9 0.4 8.7e-07 28.3 0.5 2.3 2 0 0 2 2 2 2 FMN-dependent dehydrogenase NMO PF03060.15 KXH63288.1 - 4.8e-09 36.0 2.0 0.0017 17.8 1.5 2.3 2 0 0 2 2 2 2 Nitronate monooxygenase His_biosynth PF00977.21 KXH63288.1 - 0.0001 21.8 3.3 0.016 14.7 0.2 3.0 3 1 1 4 4 4 2 Histidine biosynthesis protein YpsA PF06908.11 KXH63288.1 - 0.034 14.2 0.2 0.076 13.0 0.0 1.6 2 0 0 2 2 2 0 YspA SLOG family ThiG PF05690.14 KXH63288.1 - 0.041 13.2 1.1 0.13 11.5 0.3 2.1 1 1 1 2 2 2 0 Thiazole biosynthesis protein ThiG MFS_1 PF07690.16 KXH63289.1 - 1.1e-36 126.6 34.4 4.2e-27 95.0 4.6 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KXH63289.1 - 0.0007 18.1 0.2 0.0007 18.1 0.2 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) TFR_dimer PF04253.15 KXH63290.1 - 9.1e-27 93.6 0.0 1.7e-26 92.7 0.0 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 KXH63290.1 - 2.4e-19 69.8 0.0 4.1e-19 69.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KXH63290.1 - 5.6e-10 39.1 0.7 4.2e-09 36.3 0.1 2.3 2 0 0 2 2 2 1 PA domain NAD_binding_1 PF00175.21 KXH63291.1 - 7.5e-33 113.4 0.0 1.6e-32 112.4 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KXH63291.1 - 9.6e-23 80.4 0.0 1.7e-22 79.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 KXH63291.1 - 9.4e-10 38.8 0.0 4.3e-05 23.7 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 KXH63291.1 - 0.032 14.5 0.0 0.057 13.6 0.0 1.4 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain SH3_1 PF00018.28 KXH63292.1 - 8.4e-10 38.1 0.0 1.4e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KXH63292.1 - 5.1e-08 32.7 0.1 1.1e-07 31.6 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KXH63292.1 - 1e-05 25.1 0.0 3.5e-05 23.4 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain DSPc PF00782.20 KXH63294.1 - 3.9e-20 72.0 0.0 4.7e-13 49.1 0.0 3.3 2 1 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KXH63294.1 - 0.0028 17.3 0.1 0.027 14.0 0.1 2.1 2 0 0 2 2 2 1 Protein-tyrosine phosphatase DUF910 PF06014.11 KXH63338.1 - 0.02 14.9 0.0 0.025 14.6 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF910) SHOCT PF09851.9 KXH63338.1 - 0.038 13.7 0.0 0.05 13.3 0.0 1.2 1 0 0 1 1 1 0 Short C-terminal domain CtsR_C PF17727.1 KXH63338.1 - 0.038 14.1 0.0 0.047 13.8 0.0 1.1 1 0 0 1 1 1 0 CtsR C-terminal dimerization domain CARD PF00619.21 KXH63338.1 - 0.12 12.4 0.0 0.12 12.4 0.0 1.1 1 0 0 1 1 1 0 Caspase recruitment domain MmgE_PrpD PF03972.14 KXH63339.1 - 1.8e-148 494.7 0.0 2.1e-148 494.5 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family EAF PF09816.9 KXH63340.1 - 4.7e-23 81.5 0.0 1e-22 80.4 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor TMF_DNA_bd PF12329.8 KXH63351.1 - 0.0092 16.0 0.1 0.024 14.6 0.1 1.7 1 0 0 1 1 1 1 TATA element modulatory factor 1 DNA binding DUF3717 PF12512.8 KXH63351.1 - 0.011 15.6 0.2 0.066 13.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3717) ADIP PF11559.8 KXH63351.1 - 0.016 15.3 0.3 0.033 14.3 0.3 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Arm PF00514.23 KXH63351.1 - 0.018 15.0 1.2 1.3 9.2 0.3 2.6 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat RHINO PF15319.6 KXH63351.1 - 0.034 14.2 0.7 1 9.3 0.2 2.1 2 0 0 2 2 2 0 RAD9, RAD1, HUS1-interacting nuclear orphan protein ComZ PF10815.8 KXH63351.1 - 0.048 13.7 0.0 3.2 7.8 0.0 2.5 2 0 0 2 2 2 0 ComZ Kringle PF00051.18 KXH63351.1 - 0.094 13.0 1.2 24 5.3 0.0 3.0 3 0 0 3 3 3 0 Kringle domain DivIC PF04977.15 KXH63351.1 - 1.8 8.4 5.3 1.4 8.8 0.7 2.3 2 0 0 2 2 2 0 Septum formation initiator UIM PF02809.20 KXH63351.1 - 4.8 7.3 7.9 31 4.8 1.1 3.4 2 0 0 2 2 2 0 Ubiquitin interaction motif L71 PF02448.15 KXH63351.1 - 7.2 7.1 6.6 6.7 7.2 0.7 3.2 4 0 0 4 4 4 0 L71 family Melibiase_2 PF16499.5 KXH63353.1 - 1.2e-20 73.9 0.1 2.3e-20 73.0 0.1 1.4 1 1 0 1 1 1 1 Alpha galactosidase A Melibiase PF02065.18 KXH63353.1 - 1.2e-06 27.7 0.0 1.4e-06 27.6 0.0 1.0 1 0 0 1 1 1 1 Melibiase Raffinose_syn PF05691.12 KXH63353.1 - 1.2e-05 23.4 0.0 1.4e-05 23.2 0.0 1.0 1 0 0 1 1 1 1 Raffinose synthase or seed imbibition protein Sip1 TrbC PF04956.13 KXH63353.1 - 0.006 16.8 0.0 0.0078 16.4 0.0 1.1 1 0 0 1 1 1 1 TrbC/VIRB2 family Fasciclin PF02469.22 KXH63354.1 - 8.5e-18 64.8 0.0 1.2e-17 64.4 0.0 1.1 1 0 0 1 1 1 1 Fasciclin domain SRF-TF PF00319.18 KXH63356.1 - 5.9e-21 73.7 0.1 8.2e-21 73.2 0.1 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) MRI PF15325.6 KXH63356.1 - 1.2 10.3 3.8 0.94 10.6 0.5 2.1 2 0 0 2 2 2 0 Modulator of retrovirus infection DUF2273 PF10031.9 KXH63372.1 - 0.026 14.5 5.1 0.026 14.5 5.1 2.5 2 0 0 2 2 2 0 Small integral membrane protein (DUF2273) Ion_trans PF00520.31 KXH63372.1 - 0.035 13.3 1.8 0.043 13.0 1.8 1.2 1 0 0 1 1 1 0 Ion transport protein Ank_2 PF12796.7 KXH63373.1 - 1.4e-44 150.5 13.2 2.5e-09 37.6 0.0 7.8 4 2 3 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXH63373.1 - 5.3e-31 106.6 4.2 2.5e-06 27.9 0.1 9.8 6 3 4 10 10 10 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXH63373.1 - 1.9e-28 95.4 15.2 0.00055 20.2 0.1 13.1 14 0 0 14 14 14 5 Ankyrin repeat Ank_5 PF13857.6 KXH63373.1 - 7.1e-28 96.3 9.3 6.5e-07 29.5 0.0 9.6 4 2 6 10 10 10 6 Ankyrin repeats (many copies) Ank PF00023.30 KXH63373.1 - 3.4e-23 81.0 21.0 0.0031 17.9 0.0 11.3 12 0 0 12 12 11 4 Ankyrin repeat Cutinase PF01083.22 KXH63373.1 - 1.4e-05 25.1 0.0 0.00044 20.3 0.0 2.4 2 0 0 2 2 2 1 Cutinase DUF676 PF05057.14 KXH63373.1 - 4.7e-05 23.0 0.0 9.4e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 KXH63373.1 - 0.00024 20.9 0.0 0.0005 19.8 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein Hydrolase_4 PF12146.8 KXH63373.1 - 0.00024 20.4 0.1 0.00096 18.5 0.0 2.1 3 0 0 3 3 3 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KXH63373.1 - 0.00067 20.3 0.0 0.0038 17.9 0.0 2.3 2 0 0 2 2 2 1 Alpha/beta hydrolase family AAA_16 PF13191.6 KXH63373.1 - 0.0031 17.9 0.0 0.034 14.5 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KXH63373.1 - 0.0035 17.6 0.1 0.033 14.5 0.0 2.5 1 1 1 2 2 2 1 AAA domain LCAT PF02450.15 KXH63373.1 - 0.0053 16.0 0.0 0.031 13.5 0.0 2.2 2 0 0 2 2 2 1 Lecithin:cholesterol acyltransferase Abhydrolase_9 PF10081.9 KXH63373.1 - 0.034 13.2 0.0 0.075 12.1 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta-hydrolase family Esterase PF00756.20 KXH63373.1 - 0.038 13.6 0.0 0.08 12.6 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Acetyltransf_1 PF00583.25 KXH63375.1 - 8.3e-18 64.7 0.0 1e-17 64.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXH63375.1 - 8.8e-11 41.8 0.0 1.2e-10 41.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXH63375.1 - 2.8e-10 40.5 0.0 4e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KXH63375.1 - 2.5e-08 34.7 0.0 3e-08 34.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KXH63375.1 - 0.0001 22.3 0.0 0.00013 22.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KXH63375.1 - 0.00015 21.9 0.0 0.00024 21.3 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KXH63375.1 - 0.00017 21.7 0.0 0.00037 20.6 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 KXH63375.1 - 0.00071 19.5 0.0 0.0011 18.9 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_13 PF13880.6 KXH63375.1 - 0.058 13.4 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Methyltransf_1N PF02870.15 KXH63375.1 - 0.061 14.1 0.0 0.1 13.4 0.0 1.4 1 0 0 1 1 1 0 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain Acetyltransf_5 PF13444.6 KXH63375.1 - 0.069 13.9 0.0 0.14 12.9 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain GNAT_acetyltr_2 PF13718.6 KXH63375.1 - 0.11 11.9 0.0 1.1 8.6 0.0 2.0 2 0 0 2 2 2 0 GNAT acetyltransferase 2 FAD_binding_4 PF01565.23 KXH63376.1 - 6.2e-27 94.0 0.8 1.3e-26 93.0 0.8 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KXH63376.1 - 0.011 15.8 0.1 0.022 14.9 0.1 1.5 1 0 0 1 1 1 0 Berberine and berberine like DUF1996 PF09362.10 KXH63377.1 - 1.2e-44 153.1 0.3 1.6e-44 152.7 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) WSC PF01822.19 KXH63378.1 - 2.6e-13 50.0 4.5 2.6e-13 50.0 4.5 4.0 4 1 0 4 4 4 1 WSC domain MFS_1 PF07690.16 KXH63379.1 - 4.1e-41 141.1 31.2 4.1e-41 141.1 31.2 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily HET PF06985.11 KXH63379.1 - 7e-34 117.3 0.1 1.7e-33 116.0 0.1 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Sugar_tr PF00083.24 KXH63379.1 - 3.4e-10 39.4 4.9 3.4e-10 39.4 4.9 2.9 3 0 0 3 3 3 1 Sugar (and other) transporter OATP PF03137.20 KXH63379.1 - 0.0002 19.8 11.8 0.0071 14.7 0.7 2.7 2 1 1 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family LAB_N PF07578.11 KXH63379.1 - 0.039 14.0 0.5 0.12 12.4 0.5 1.8 1 0 0 1 1 1 0 Lipid A Biosynthesis N-terminal domain YhfC PF10086.9 KXH63379.1 - 0.045 13.1 0.3 0.045 13.1 0.3 1.8 2 0 0 2 2 2 0 YhfC intramembrane metalloprotease UDPGT PF00201.18 KXH63380.1 - 3.3e-10 39.4 0.0 4.9e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_transf_28 PF03033.20 KXH63380.1 - 0.1 12.6 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase family 28 N-terminal domain TPR_2 PF07719.17 KXH63381.1 - 1e-10 40.9 4.5 0.0084 16.2 0.0 4.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 KXH63381.1 - 4.9e-08 32.5 0.1 0.012 15.4 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 KXH63381.1 - 7.6e-07 29.3 0.9 0.17 12.2 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 KXH63381.1 - 0.00016 21.2 0.0 1 9.1 0.0 4.3 4 1 1 5 5 5 2 TPR repeat TPR_8 PF13181.6 KXH63381.1 - 0.00031 20.7 0.1 2.6 8.5 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 KXH63381.1 - 0.00034 21.2 8.7 0.00067 20.2 0.8 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 KXH63381.1 - 0.0083 16.3 0.7 0.084 13.0 0.1 3.0 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 KXH63381.1 - 0.014 15.4 0.6 6.5 7.0 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat WXG100 PF06013.12 KXH63381.1 - 0.028 14.6 0.1 0.088 13.0 0.1 1.9 1 0 0 1 1 1 0 Proteins of 100 residues with WXG SHNi-TPR PF10516.9 KXH63381.1 - 0.043 13.3 0.0 0.12 11.9 0.0 1.7 1 0 0 1 1 1 0 SHNi-TPR TPR_14 PF13428.6 KXH63381.1 - 0.12 13.3 17.1 0.21 12.5 0.1 5.8 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 KXH63381.1 - 0.2 12.4 4.2 30 5.5 0.1 4.3 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 KXH63381.1 - 0.44 11.1 5.5 5.4 7.6 0.1 4.0 4 1 1 5 5 4 0 Tetratricopeptide repeat GYF PF02213.16 KXH63382.1 - 8.5e-19 67.0 0.3 1.8e-18 65.9 0.3 1.6 1 0 0 1 1 1 1 GYF domain GYF_2 PF14237.6 KXH63382.1 - 0.0047 16.7 0.0 0.014 15.2 0.0 1.9 1 0 0 1 1 1 1 GYF domain 2 Med26 PF08711.11 KXH63383.1 - 0.038 14.0 0.0 0.079 13.0 0.0 1.6 1 0 0 1 1 1 0 TFIIS helical bundle-like domain DUF1304 PF06993.12 KXH63384.1 - 2.3e-43 146.7 1.8 2.6e-43 146.5 1.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1304) Dynamin_N PF00350.23 KXH63385.1 - 3.2e-18 66.4 1.6 1e-17 64.7 0.0 2.4 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 KXH63385.1 - 1.4e-05 25.1 0.0 0.00017 21.7 0.0 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KXH63385.1 - 0.00043 20.7 0.7 0.0055 17.1 0.0 3.2 4 0 0 4 4 3 1 AAA ATPase domain NPV_P10 PF05531.12 KXH63385.1 - 0.00052 20.4 2.1 7.4 7.1 0.0 4.5 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein RsgA_GTPase PF03193.16 KXH63385.1 - 0.00073 19.5 0.0 0.0069 16.3 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase CENP-F_leu_zip PF10473.9 KXH63385.1 - 0.0016 18.5 11.5 0.074 13.1 0.2 3.6 3 0 0 3 3 3 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ABC_tran PF00005.27 KXH63385.1 - 0.0017 18.9 0.0 0.0017 18.9 0.0 2.8 2 1 0 2 2 1 1 ABC transporter APG6_N PF17675.1 KXH63385.1 - 0.0061 17.1 13.7 0.11 13.1 4.8 3.5 3 0 0 3 3 3 2 Apg6 coiled-coil region AAA_22 PF13401.6 KXH63385.1 - 0.011 16.0 0.1 0.24 11.7 0.0 3.1 2 1 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KXH63385.1 - 0.022 14.0 0.0 0.086 12.1 0.0 2.0 1 0 0 1 1 1 0 Zeta toxin IIGP PF05049.13 KXH63385.1 - 0.033 13.2 0.0 0.078 12.0 0.0 1.5 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AIG1 PF04548.16 KXH63385.1 - 0.043 13.1 0.0 0.17 11.2 0.0 2.0 2 0 0 2 2 2 0 AIG1 family Spc7 PF08317.11 KXH63385.1 - 0.18 10.7 9.6 3.1 6.6 0.3 3.4 4 0 0 4 4 4 0 Spc7 kinetochore protein NAM-associated PF14303.6 KXH63385.1 - 0.25 12.0 12.3 0.77 10.5 12.3 1.8 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain YabA PF06156.13 KXH63385.1 - 0.5 11.0 3.3 28 5.4 0.6 3.6 3 0 0 3 3 2 0 Initiation control protein YabA DUF4140 PF13600.6 KXH63385.1 - 1.2 9.7 10.0 10 6.6 0.3 3.5 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) BLOC1_2 PF10046.9 KXH63385.1 - 1.7 9.0 5.6 12 6.3 0.0 3.4 3 0 0 3 3 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TPR_MLP1_2 PF07926.12 KXH63385.1 - 1.9 8.5 11.1 3.7 7.6 0.2 3.5 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein DASH_Dad2 PF08654.10 KXH63385.1 - 2 8.9 8.1 1.8 9.1 0.1 3.7 2 1 1 3 3 3 0 DASH complex subunit Dad2 DUF1043 PF06295.12 KXH63385.1 - 2.2 8.3 9.9 1.1 9.3 0.3 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1043) DUF908 PF06012.12 KXH63385.1 - 2.5 7.4 7.1 5 6.4 7.1 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Fungal_TACC PF12709.7 KXH63385.1 - 3.4 8.2 9.4 1.3 9.5 0.4 2.9 2 0 0 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins Fib_alpha PF08702.10 KXH63385.1 - 3.4 7.8 7.0 22 5.2 0.3 3.9 4 0 0 4 4 3 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.12 KXH63385.1 - 3.8 7.6 4.8 3.2 7.8 0.6 2.8 3 0 0 3 3 2 0 Protein of unknown function (DUF1664) Spc24 PF08286.11 KXH63385.1 - 5.6 7.3 10.2 5 7.4 0.3 3.8 3 0 0 3 3 3 0 Spc24 subunit of Ndc80 DUF4661 PF15576.6 KXH63385.1 - 7.6 6.4 8.1 16 5.3 8.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) DivIC PF04977.15 KXH63385.1 - 8.6 6.2 9.0 57 3.6 0.1 3.1 2 0 0 2 2 2 0 Septum formation initiator Tugs PF17840.1 KXH63386.1 - 0.099 12.8 1.0 0.24 11.6 1.0 1.6 1 0 0 1 1 1 0 Tethering Ubl4a to BAGS domain Beta-lactamase PF00144.24 KXH63387.1 - 1.1e-51 176.0 0.7 1.5e-51 175.6 0.7 1.1 1 0 0 1 1 1 1 Beta-lactamase CHASE PF03924.13 KXH63387.1 - 0.15 12.0 0.0 11 5.9 0.0 2.3 2 0 0 2 2 2 0 CHASE domain DUF3425 PF11905.8 KXH63388.1 - 2.7e-14 53.2 0.0 8.4e-14 51.6 0.0 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) Mto2_bdg PF12808.7 KXH63388.1 - 0.00093 19.4 8.0 0.0074 16.6 7.8 2.5 2 1 0 2 2 2 1 Micro-tubular organiser Mto1 C-term Mto2-binding region bZIP_1 PF00170.21 KXH63388.1 - 0.014 15.5 16.3 0.082 13.0 16.3 2.1 1 1 0 1 1 1 0 bZIP transcription factor HAUS-augmin3 PF14932.6 KXH63388.1 - 0.062 12.9 5.9 0.094 12.3 5.9 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF1471 PF07338.13 KXH63388.1 - 0.079 13.0 0.0 0.22 11.5 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1471) Fib_alpha PF08702.10 KXH63388.1 - 0.15 12.2 5.8 0.3 11.3 5.8 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family ZapB PF06005.12 KXH63388.1 - 0.34 11.4 8.6 0.77 10.2 8.6 1.7 1 1 0 1 1 1 0 Cell division protein ZapB UPF0242 PF06785.11 KXH63388.1 - 0.35 10.9 7.8 0.62 10.1 7.8 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Med21 PF11221.8 KXH63388.1 - 0.4 10.9 6.4 0.089 13.0 2.1 2.0 1 1 1 2 2 2 0 Subunit 21 of Mediator complex Jnk-SapK_ap_N PF09744.9 KXH63388.1 - 0.49 10.6 11.2 0.81 9.9 11.2 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 DUF4763 PF15960.5 KXH63388.1 - 0.81 8.9 9.7 3.2 7.0 9.7 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4763) DUF5320 PF17253.2 KXH63388.1 - 1.3 10.2 3.2 2.3 9.4 3.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5320) Beta_elim_lyase PF01212.21 KXH63389.1 - 6.4e-39 134.0 0.0 8.6e-39 133.6 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 KXH63389.1 - 1.8e-05 24.1 0.0 2.5e-05 23.6 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KXH63389.1 - 0.001 18.1 0.0 0.0013 17.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Toprim PF01751.22 KXH63389.1 - 0.13 12.5 0.0 0.37 11.1 0.0 1.7 1 1 0 1 1 1 0 Toprim domain AhpC-TSA_2 PF13911.6 KXH63390.1 - 2e-05 24.6 0.0 3.1e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 KXH63390.1 - 8.8e-05 22.4 0.0 0.00011 22.2 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KXH63390.1 - 0.14 11.9 0.0 0.29 10.8 0.0 1.5 1 1 0 2 2 2 0 Redoxin Cyt-b5 PF00173.28 KXH63391.1 - 5.7e-13 48.8 0.0 5.9e-07 29.5 0.0 4.2 4 0 0 4 4 4 3 Cytochrome b5-like Heme/Steroid binding domain Cyt-b5 PF00173.28 KXH63392.1 - 1.4e-12 47.6 0.1 4.5e-11 42.7 0.0 3.3 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain ABC_tran PF00005.27 KXH63393.1 - 1.6e-47 161.5 0.2 1e-23 84.4 0.0 3.9 2 2 0 2 2 2 2 ABC transporter 4HB PF17947.1 KXH63393.1 - 6.6e-27 93.4 0.3 6.6e-27 93.4 0.3 2.1 2 0 0 2 2 1 1 Four helical bundle domain AAA_21 PF13304.6 KXH63393.1 - 7e-18 65.5 0.0 0.002 18.0 0.0 5.3 5 0 0 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KXH63393.1 - 4.5e-16 58.9 0.6 2.1e-05 24.1 0.1 4.1 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KXH63393.1 - 1.8e-09 38.4 5.4 0.0003 21.4 0.1 3.3 3 1 0 3 3 2 2 AAA domain RsgA_GTPase PF03193.16 KXH63393.1 - 9.1e-09 35.4 0.1 0.00012 22.0 0.0 2.9 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 KXH63393.1 - 1.3e-08 34.4 0.1 0.0047 16.6 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KXH63393.1 - 2e-07 31.1 0.0 0.0019 18.3 0.0 3.2 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.6 KXH63393.1 - 9.2e-07 29.2 0.0 0.015 15.6 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_28 PF13521.6 KXH63393.1 - 1e-06 29.1 0.0 0.017 15.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 KXH63393.1 - 1.2e-06 28.5 0.9 0.059 13.1 0.0 4.2 5 0 0 5 5 4 2 AAA ATPase domain AAA_18 PF13238.6 KXH63393.1 - 6.8e-06 26.7 0.2 0.15 12.6 0.0 3.5 4 0 0 4 4 2 2 AAA domain AAA PF00004.29 KXH63393.1 - 1.6e-05 25.4 0.0 0.39 11.1 0.0 4.2 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KXH63393.1 - 1.7e-05 25.2 0.1 0.23 11.8 0.0 3.7 4 0 0 4 4 3 2 AAA ATPase domain PduV-EutP PF10662.9 KXH63393.1 - 5e-05 23.1 0.1 0.053 13.3 0.0 3.0 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.23 KXH63393.1 - 5.5e-05 23.3 1.7 0.0022 18.0 0.0 3.1 4 0 0 4 4 2 1 Dynamin family AAA_33 PF13671.6 KXH63393.1 - 6.3e-05 23.2 0.0 0.53 10.4 0.0 3.0 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 KXH63393.1 - 8e-05 23.0 0.0 0.95 9.9 0.0 3.1 2 0 0 2 2 2 2 RNA helicase MeaB PF03308.16 KXH63393.1 - 0.00016 20.8 1.5 0.36 9.8 0.0 2.8 3 0 0 3 3 3 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_27 PF13514.6 KXH63393.1 - 0.00022 20.9 0.0 0.14 11.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 KXH63393.1 - 0.00043 20.3 0.0 0.43 10.5 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain G-alpha PF00503.20 KXH63393.1 - 0.00055 19.2 0.1 0.74 8.9 0.0 3.1 3 1 0 3 3 3 1 G-protein alpha subunit AAA_24 PF13479.6 KXH63393.1 - 0.00065 19.5 0.3 1.3 8.7 0.0 3.2 3 0 0 3 3 3 1 AAA domain NACHT PF05729.12 KXH63393.1 - 0.00068 19.6 0.0 0.19 11.7 0.0 2.5 2 0 0 2 2 2 1 NACHT domain MMS19_N PF14500.6 KXH63393.1 - 0.00092 18.9 0.7 0.22 11.1 0.5 2.8 2 0 0 2 2 2 1 Dos2-interacting transcription regulator of RNA-Pol-II DUF87 PF01935.17 KXH63393.1 - 0.00099 19.3 1.5 1.1 9.3 0.0 4.2 5 0 0 5 5 4 1 Helicase HerA, central domain AAA_14 PF13173.6 KXH63393.1 - 0.0016 18.4 0.0 4.5 7.3 0.0 3.4 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.6 KXH63393.1 - 0.0024 17.6 0.0 3.2 7.4 0.0 3.2 3 0 0 3 3 3 1 AAA domain cobW PF02492.19 KXH63393.1 - 0.0028 17.3 0.3 4.2 6.9 0.0 3.5 4 0 0 4 4 3 0 CobW/HypB/UreG, nucleotide-binding domain SbcCD_C PF13558.6 KXH63393.1 - 0.0037 17.5 0.0 1.1 9.6 0.0 3.4 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit NB-ARC PF00931.22 KXH63393.1 - 0.0056 15.9 0.1 0.31 10.2 0.0 2.6 2 0 0 2 2 2 1 NB-ARC domain Roc PF08477.13 KXH63393.1 - 0.0066 16.7 0.1 9.5 6.5 0.0 3.3 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase PRK PF00485.18 KXH63393.1 - 0.0066 16.2 0.0 0.39 10.4 0.0 2.5 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family ATPase_2 PF01637.18 KXH63393.1 - 0.0098 15.8 0.0 3.2 7.6 0.0 3.2 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea ATP_bind_1 PF03029.17 KXH63393.1 - 0.014 15.2 0.0 7.8 6.2 0.0 2.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein CLP1_P PF16575.5 KXH63393.1 - 0.019 14.8 0.0 0.8 9.5 0.0 2.7 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Septin PF00735.18 KXH63393.1 - 0.02 14.2 0.2 4.1 6.6 0.0 2.9 3 0 0 3 3 3 0 Septin Ploopntkinase3 PF18751.1 KXH63393.1 - 0.02 14.8 0.1 3.4 7.5 0.0 2.4 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 DRIM PF07539.12 KXH63393.1 - 0.026 12.9 2.5 0.33 9.2 0.3 2.3 2 0 0 2 2 2 0 Down-regulated in metastasis IstB_IS21 PF01695.17 KXH63393.1 - 0.027 14.2 0.0 5.6 6.7 0.0 2.9 3 0 0 3 3 2 0 IstB-like ATP binding protein AAA_7 PF12775.7 KXH63393.1 - 0.029 13.9 0.0 4.1 6.9 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_13 PF13166.6 KXH63393.1 - 0.032 12.9 3.7 2.4 6.7 0.0 3.8 4 0 0 4 4 3 0 AAA domain Mg_chelatase PF01078.21 KXH63393.1 - 0.042 13.2 0.0 3.7 6.9 0.0 2.9 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI ATP-synt_ab PF00006.25 KXH63393.1 - 0.042 13.5 0.0 13 5.3 0.0 2.6 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Cytidylate_kin PF02224.18 KXH63393.1 - 0.044 13.5 0.0 12 5.6 0.0 2.7 2 0 0 2 2 2 0 Cytidylate kinase RPN6_C_helix PF18503.1 KXH63393.1 - 0.053 13.3 1.1 0.094 12.5 0.1 2.0 2 0 0 2 2 1 0 26S proteasome subunit RPN6 C-terminal helix domain DUF1280 PF06918.14 KXH63393.1 - 0.076 12.6 0.5 0.25 10.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1280) NTPase_1 PF03266.15 KXH63393.1 - 0.077 12.9 0.1 20 5.0 0.1 2.9 2 0 0 2 2 2 0 NTPase HEAT PF02985.22 KXH63393.1 - 0.12 12.7 0.0 37 4.9 0.0 3.6 3 0 0 3 3 2 0 HEAT repeat FeoB_N PF02421.18 KXH63393.1 - 0.13 11.7 0.2 1.1 8.8 0.1 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B TsaE PF02367.17 KXH63393.1 - 0.13 12.2 0.1 55 3.8 0.0 3.2 2 1 1 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MukB PF04310.12 KXH63393.1 - 0.15 11.8 0.0 17 5.1 0.0 2.4 2 0 0 2 2 2 0 MukB N-terminal SpoIIIAH PF12685.7 KXH63393.1 - 0.39 10.5 6.1 0.1 12.4 1.1 2.5 2 1 1 3 3 3 0 SpoIIIAH-like protein COMP PF11598.8 KXH63404.1 - 0.13 12.8 0.2 0.22 12.0 0.2 1.3 1 0 0 1 1 1 0 Cartilage oligomeric matrix protein CENP-B_dimeris PF09026.10 KXH63404.1 - 0.22 11.9 8.6 0.43 11.0 8.6 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain ZapA PF05164.13 KXH63404.1 - 0.51 10.8 2.9 0.97 9.9 2.9 1.4 1 0 0 1 1 1 0 Cell division protein ZapA CDC45 PF02724.14 KXH63404.1 - 0.83 7.9 6.8 1.2 7.3 6.8 1.2 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 KXH63404.1 - 2.2 7.5 9.5 3.3 7.0 9.5 1.2 1 0 0 1 1 1 0 NOA36 protein Nop53 PF07767.11 KXH63404.1 - 4.9 6.4 10.5 7.9 5.7 10.5 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) HlyIII PF03006.20 KXH63406.1 - 1.3e-14 54.5 8.8 1.8e-14 54.0 8.8 1.1 1 0 0 1 1 1 1 Haemolysin-III related ADH_zinc_N_2 PF13602.6 KXH63407.1 - 5.6e-19 69.5 0.3 1.4e-18 68.2 0.2 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KXH63407.1 - 1.5e-12 47.6 1.5 2.8e-12 46.7 1.5 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KXH63407.1 - 0.029 13.8 0.6 0.051 13.1 0.6 1.3 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus Helo_like_N PF17111.5 KXH63419.1 - 1.6e-80 269.4 13.0 3.3e-76 255.3 4.2 2.0 2 0 0 2 2 2 2 Fungal N-terminal domain of STAND proteins SesA PF17107.5 KXH63419.1 - 0.00011 22.4 1.6 0.00022 21.4 0.1 2.2 3 0 0 3 3 3 1 N-terminal domain on NACHT_NTPase and P-loop NTPases Rx_N PF18052.1 KXH63419.1 - 0.00094 19.4 1.6 0.39 11.0 0.0 3.7 3 2 1 4 4 4 1 Rx N-terminal domain Phasin PF05597.11 KXH63419.1 - 0.04 13.9 2.4 0.24 11.4 0.1 2.7 3 0 0 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF1043 PF06295.12 KXH63419.1 - 0.053 13.5 3.5 3.2 7.8 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1043) Laminin_II PF06009.12 KXH63419.1 - 0.073 13.1 4.7 1.7 8.7 0.0 3.3 3 1 0 3 3 3 0 Laminin Domain II Spore_YpjB PF09577.10 KXH63419.1 - 0.082 12.7 4.2 4.7 6.9 0.7 2.5 3 0 0 3 3 3 0 Sporulation protein YpjB (SpoYpjB) NPV_P10 PF05531.12 KXH63419.1 - 0.11 13.0 7.7 1.5 9.3 1.1 3.2 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Cob_adeno_trans PF01923.18 KXH63419.1 - 0.12 12.5 3.7 16 5.6 0.0 3.1 2 1 0 3 3 3 0 Cobalamin adenosyltransferase SLATT_5 PF18160.1 KXH63419.1 - 0.15 11.3 0.7 0.35 10.2 0.7 1.6 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 DUF2959 PF11172.8 KXH63419.1 - 0.16 12.1 2.8 1.2 9.2 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2959) Spectrin PF00435.21 KXH63419.1 - 0.18 12.3 4.3 5.1 7.6 0.3 3.1 3 0 0 3 3 3 0 Spectrin repeat DUF2730 PF10805.8 KXH63419.1 - 0.24 11.5 2.8 2.5 8.3 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2730) SHE3 PF17078.5 KXH63419.1 - 0.24 11.1 6.0 0.46 10.2 0.3 2.7 3 0 0 3 3 3 0 SWI5-dependent HO expression protein 3 DUF948 PF06103.11 KXH63419.1 - 0.29 11.4 6.5 7.4 6.9 0.1 3.0 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) FAM184 PF15665.5 KXH63419.1 - 0.3 10.9 4.6 0.83 9.4 0.4 2.6 3 0 0 3 3 3 0 Family with sequence similarity 184, A and B TMPIT PF07851.13 KXH63419.1 - 0.34 10.1 3.3 7 5.8 0.0 2.9 3 0 0 3 3 3 0 TMPIT-like protein Spc7 PF08317.11 KXH63419.1 - 0.47 9.3 5.2 2.5 6.9 0.1 2.9 3 0 0 3 3 3 0 Spc7 kinetochore protein SKA2 PF16740.5 KXH63419.1 - 0.97 9.2 7.7 15 5.4 0.2 3.2 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 2 Prefoldin PF02996.17 KXH63419.1 - 1.2 9.0 6.5 17 5.4 0.4 4.0 3 1 0 3 3 3 0 Prefoldin subunit DUF1690 PF07956.11 KXH63419.1 - 1.4 9.4 7.3 3.7 8.0 0.2 3.1 3 0 0 3 3 3 0 Protein of Unknown function (DUF1690) ATG16 PF08614.11 KXH63419.1 - 1.5 9.0 8.7 2 8.6 0.3 2.7 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF4481 PF14800.6 KXH63419.1 - 1.5 8.2 4.4 1.9 7.9 0.2 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4481) BLOC1_2 PF10046.9 KXH63419.1 - 1.6 9.0 8.0 12 6.2 0.1 3.0 3 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fib_alpha PF08702.10 KXH63419.1 - 1.7 8.9 12.7 0.9 9.7 0.8 3.3 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family DUF16 PF01519.16 KXH63419.1 - 2 8.9 5.7 4.6 7.8 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function DUF16 Med10 PF09748.9 KXH63419.1 - 3.8 7.5 5.3 13 5.8 1.1 2.8 3 0 0 3 3 3 0 Transcription factor subunit Med10 of Mediator complex Muted PF14942.6 KXH63419.1 - 3.9 7.8 8.3 8.3 6.8 0.2 3.1 3 0 0 3 3 3 0 Organelle biogenesis, Muted-like protein DASH_Dad3 PF08656.10 KXH63419.1 - 5.5 7.1 6.1 25 5.0 0.1 3.0 3 1 0 3 3 3 0 DASH complex subunit Dad3 DUF3328 PF11807.8 KXH63420.1 - 4.1e-18 66.0 0.1 4.8e-18 65.7 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.8 KXH63421.1 - 0.03 14.1 5.4 0.5 10.1 0.1 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF3328) YqaJ PF09588.10 KXH63421.1 - 0.12 12.5 0.1 0.19 11.9 0.1 1.3 1 0 0 1 1 1 0 YqaJ-like viral recombinase domain Ribosomal_S28e PF01200.18 KXH63423.1 - 0.00093 19.1 2.2 11 6.1 0.0 4.1 1 1 3 4 4 4 1 Ribosomal protein S28e TT1725 PF18324.1 KXH63423.1 - 0.02 15.0 0.0 0.62 10.2 0.0 2.1 1 1 1 2 2 2 0 Hypothetical protein TT1725 Dehydratase_LU PF02286.15 KXH63423.1 - 0.026 13.1 0.4 1.1 7.7 0.2 2.1 1 1 1 2 2 2 0 Dehydratase large subunit DUF5317 PF17248.2 KXH63423.1 - 0.066 13.2 1.4 5.5 7.0 0.2 2.8 1 1 3 4 4 4 0 Family of unknown function (DUF5317) BHD_2 PF10404.9 KXH63423.1 - 1.4 9.9 2.9 93 4.1 0.0 3.7 4 0 0 4 4 4 0 Rad4 beta-hairpin domain 2 ProQ_C PF17516.2 KXH63423.1 - 4 6.9 6.7 43 3.6 0.1 3.4 1 1 2 3 3 3 0 ProQ C-terminal domain Ank_2 PF12796.7 KXH63424.1 - 1.2e-52 176.4 6.1 1.5e-12 47.9 0.1 4.9 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXH63424.1 - 4.4e-39 132.4 8.8 3e-08 34.0 0.0 5.8 3 2 4 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXH63424.1 - 7e-34 112.0 4.8 0.0076 16.7 0.0 8.1 8 0 0 8 8 8 8 Ankyrin repeat Ank PF00023.30 KXH63424.1 - 1.6e-30 104.2 16.1 0.00043 20.6 0.1 8.1 8 0 0 8 8 8 8 Ankyrin repeat Ank_5 PF13857.6 KXH63424.1 - 2.4e-14 53.2 10.9 0.00038 20.7 0.1 6.8 3 2 5 8 8 8 3 Ankyrin repeats (many copies) DUF1843 PF08898.10 KXH63424.1 - 0.5 10.9 0.0 0.5 10.9 0.0 3.3 5 0 0 5 5 5 0 Domain of unknown function (DUF1843) Nitro_FeMo-Co PF02579.17 KXH63424.1 - 0.85 10.0 3.0 26 5.2 0.0 3.8 3 1 2 5 5 5 0 Dinitrogenase iron-molybdenum cofactor DUF3328 PF11807.8 KXH63425.1 - 1.2e-21 77.5 0.0 1.4e-21 77.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) p450 PF00067.22 KXH63426.1 - 1.6e-23 83.2 0.0 4.9e-12 45.3 0.0 2.1 1 1 1 2 2 2 2 Cytochrome P450 HET PF06985.11 KXH63427.1 - 3.8e-31 108.4 1.1 1.1e-30 106.9 1.1 1.9 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) AMP-binding PF00501.28 KXH63457.1 - 0.008 14.8 0.0 0.015 14.0 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme Acyl-CoA_dh_1 PF00441.24 KXH63458.1 - 2.5e-28 99.2 0.4 3.7e-28 98.6 0.4 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KXH63458.1 - 1.4e-24 86.1 0.0 2.4e-24 85.4 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KXH63458.1 - 2e-21 76.8 0.0 6.2e-21 75.2 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KXH63458.1 - 1.8e-05 25.0 0.3 3.5e-05 24.1 0.3 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain 4HBT PF03061.22 KXH63459.1 - 3.8e-07 30.4 0.0 6e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily adh_short PF00106.25 KXH63460.1 - 4.9e-35 120.8 0.0 6e-35 120.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXH63460.1 - 7.5e-17 61.7 0.0 9.2e-17 61.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH63460.1 - 3.7e-06 27.0 0.1 7.6e-06 26.0 0.1 1.4 1 1 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 KXH63460.1 - 0.003 17.8 0.1 0.0054 17.0 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 KXH63460.1 - 0.016 15.1 0.0 0.023 14.6 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding Epimerase PF01370.21 KXH63460.1 - 0.041 13.3 0.1 0.084 12.3 0.1 1.5 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.17 KXH63460.1 - 0.049 14.2 0.1 0.13 12.8 0.1 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 KXH63460.1 - 0.16 12.2 0.0 0.34 11.1 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase DUF1992 PF09350.10 KXH63461.1 - 1.6e-20 73.0 0.4 1.6e-20 73.0 0.4 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF1992) TRCF PF03461.15 KXH63461.1 - 0.027 14.8 0.0 0.065 13.6 0.0 1.6 1 0 0 1 1 1 0 TRCF domain p450 PF00067.22 KXH63462.1 - 3e-36 125.2 0.0 3.7e-36 124.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FMN_dh PF01070.18 KXH63463.1 - 1.6e-128 428.6 0.1 1.9e-128 428.4 0.1 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 KXH63463.1 - 5e-11 42.2 1.2 1.1e-10 41.1 0.3 2.1 2 1 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 KXH63463.1 - 3e-09 36.7 0.2 5.2e-09 36.0 0.2 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase Glu_synthase PF01645.17 KXH63463.1 - 1.7e-06 27.5 0.6 3e-06 26.6 0.6 1.4 1 1 0 1 1 1 1 Conserved region in glutamate synthase ThiG PF05690.14 KXH63463.1 - 5.9e-06 25.8 1.3 0.0013 18.1 0.2 2.5 2 1 1 3 3 3 2 Thiazole biosynthesis protein ThiG DHO_dh PF01180.21 KXH63463.1 - 6.1e-05 22.4 0.4 0.00057 19.2 0.1 2.1 1 1 1 2 2 2 1 Dihydroorotate dehydrogenase His_biosynth PF00977.21 KXH63463.1 - 7.7e-05 22.3 0.7 0.0067 15.9 0.1 2.4 1 1 1 2 2 2 2 Histidine biosynthesis protein Dus PF01207.17 KXH63463.1 - 0.00069 18.8 0.1 0.0016 17.6 0.0 1.6 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) G3P_antiterm PF04309.12 KXH63463.1 - 0.0009 18.7 0.2 0.93 8.9 0.0 2.4 2 0 0 2 2 2 2 Glycerol-3-phosphate responsive antiterminator PcrB PF01884.17 KXH63463.1 - 0.003 17.1 0.2 5.6 6.3 0.0 3.6 4 0 0 4 4 4 1 PcrB family Aspzincin_M35 PF14521.6 KXH63464.1 - 0.0023 18.5 0.1 1.8 9.1 0.0 2.9 3 0 0 3 3 3 2 Lysine-specific metallo-endopeptidase MFS_1 PF07690.16 KXH63465.1 - 1.9e-31 109.3 34.0 2.4e-31 109.0 34.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 KXH63465.1 - 1.5e-06 27.7 6.8 1.5e-06 27.7 6.8 2.4 2 1 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB Fungal_trans PF04082.18 KXH63466.1 - 6.2e-14 51.7 0.3 1.2e-13 50.8 0.3 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH63466.1 - 3.9e-06 26.9 6.7 7.6e-06 26.0 6.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain COesterase PF00135.28 KXH63467.1 - 1.5e-29 103.3 0.0 1.8e-29 103.0 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family DUF916 PF06030.12 KXH63468.1 - 0.11 12.6 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF916) DGF-1_C PF11040.8 KXH63470.1 - 0.088 12.8 1.0 0.53 10.3 1.0 2.3 1 0 0 1 1 1 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus Herpes_gE PF02480.16 KXH63470.1 - 0.11 11.3 0.0 0.24 10.1 0.0 1.5 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Peptidase_S8 PF00082.22 KXH63471.1 - 2.9e-24 85.9 0.0 5.9e-24 84.9 0.0 1.4 1 0 0 1 1 1 1 Subtilase family TPR_12 PF13424.6 KXH63471.1 - 2.1e-06 27.9 0.3 4.5e-05 23.7 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 KXH63471.1 - 2.8e-06 26.9 0.5 3.2e-05 23.6 0.1 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 KXH63471.1 - 0.00015 21.6 0.0 0.0044 16.9 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 KXH63471.1 - 0.00019 21.3 0.3 0.00019 21.3 0.3 2.8 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 KXH63471.1 - 0.00039 20.2 0.2 0.0035 17.1 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 KXH63471.1 - 0.0009 19.3 0.1 0.0038 17.3 0.1 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_6 PF13174.6 KXH63471.1 - 0.0046 17.5 0.0 0.029 15.0 0.0 2.5 1 0 0 1 1 1 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KXH63471.1 - 0.051 13.8 0.4 0.25 11.6 0.1 2.3 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 KXH63471.1 - 0.3 11.8 2.4 0.77 10.5 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KXH63471.1 - 0.3 12.0 2.4 0.8 10.7 0.0 3.0 3 0 0 3 3 2 0 Tetratricopeptide repeat Methyltransf_31 PF13847.6 KXH63473.1 - 6e-19 68.3 0.0 8.6e-19 67.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH63473.1 - 2.9e-18 66.3 0.0 4.5e-18 65.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXH63473.1 - 2.6e-17 63.2 0.0 3.8e-17 62.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH63473.1 - 6.2e-17 62.1 0.0 1.1e-16 61.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH63473.1 - 4.5e-14 53.0 0.0 6.7e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KXH63473.1 - 4.1e-12 46.0 0.0 4.9e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 KXH63473.1 - 9.1e-12 44.8 0.0 5.7e-10 38.9 0.0 2.1 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KXH63473.1 - 6.3e-07 29.1 0.0 1e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain MetW PF07021.12 KXH63473.1 - 1.3e-06 28.1 0.0 2.7e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.6 KXH63473.1 - 3.3e-06 27.2 0.0 4.9e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 KXH63473.1 - 1e-05 25.5 0.0 1.5e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 KXH63473.1 - 3.8e-05 22.8 0.0 5.3e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) GCD14 PF08704.10 KXH63473.1 - 0.00011 22.0 0.2 0.002 17.8 0.1 2.1 1 1 0 2 2 2 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 KXH63473.1 - 0.00016 21.5 0.0 0.00023 21.0 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) UPF0020 PF01170.18 KXH63473.1 - 0.0011 18.7 0.0 0.0017 18.1 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 NodS PF05401.11 KXH63473.1 - 0.0016 18.1 0.0 0.0023 17.6 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_PK PF05891.12 KXH63473.1 - 0.0035 16.9 0.0 0.005 16.4 0.0 1.2 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase TehB PF03848.14 KXH63473.1 - 0.0043 16.5 0.0 0.0064 15.9 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltr_RsmB-F PF01189.17 KXH63473.1 - 0.021 14.5 0.0 0.032 13.9 0.0 1.2 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F Methyltransf_4 PF02390.17 KXH63473.1 - 0.03 13.8 0.0 0.18 11.2 0.0 1.9 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_2 PF00891.18 KXH63473.1 - 0.071 12.4 0.0 0.094 12.0 0.0 1.3 1 1 0 1 1 1 0 O-methyltransferase domain RrnaAD PF00398.20 KXH63473.1 - 0.096 11.7 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase PrmA PF06325.13 KXH63473.1 - 0.12 11.8 0.0 0.16 11.3 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_5 PF01795.19 KXH63473.1 - 0.15 11.6 0.1 0.26 10.8 0.1 1.3 1 0 0 1 1 1 0 MraW methylase family Methyltransf_8 PF05148.15 KXH63473.1 - 0.2 11.5 0.0 1.3 8.8 0.0 2.0 1 1 0 1 1 1 0 Hypothetical methyltransferase Peptidase_M49 PF03571.15 KXH63474.1 - 7.8e-202 671.5 0.0 9.1e-202 671.3 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M49 UDPGT PF00201.18 KXH63475.1 - 6.8e-05 21.8 0.1 7.9e-05 21.6 0.1 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase HET PF06985.11 KXH63476.1 - 3.5e-24 85.8 0.0 6.3e-24 85.0 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF2653 PF10850.8 KXH63477.1 - 0.13 12.5 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2653) DUF2157 PF09925.9 KXH63478.1 - 0.097 12.5 4.2 0.15 11.8 4.2 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) Gate PF07670.14 KXH63478.1 - 0.71 10.2 3.0 9.2 6.6 1.2 2.2 2 0 0 2 2 2 0 Nucleoside recognition Ank_2 PF12796.7 KXH63479.1 - 1e-14 54.8 0.0 1.6e-06 28.6 0.0 3.9 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXH63479.1 - 9.2e-09 35.4 0.1 0.11 12.8 0.0 4.4 3 1 1 4 4 4 3 Ankyrin repeats (many copies) CorA PF01544.18 KXH63479.1 - 1e-08 34.8 0.2 1e-08 34.8 0.2 2.4 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein Ank_3 PF13606.6 KXH63479.1 - 1.1e-08 34.6 0.0 3.5 8.5 0.0 5.6 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.6 KXH63479.1 - 2.9e-08 34.1 0.0 0.0097 16.5 0.0 4.3 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 KXH63479.1 - 6.7e-07 29.5 0.0 0.84 10.2 0.0 4.7 5 0 0 5 5 5 2 Ankyrin repeat Abhydrolase_2 PF02230.16 KXH63480.1 - 5.3e-22 78.7 0.0 2.8e-21 76.3 0.0 2.1 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 KXH63480.1 - 0.0051 16.1 0.1 0.63 9.3 0.0 2.6 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KXH63480.1 - 0.0064 16.0 0.0 0.0095 15.4 0.0 1.4 1 1 0 1 1 1 1 Prolyl oligopeptidase family LIP PF03583.14 KXH63480.1 - 0.02 14.2 0.0 0.06 12.7 0.0 1.6 1 1 1 2 2 2 0 Secretory lipase PGM_PMM_IV PF00408.20 KXH63480.1 - 0.023 14.9 0.0 0.04 14.1 0.0 1.4 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, C-terminal domain MgsA_C PF12002.8 KXH63481.1 - 1.7e-60 203.8 0.1 2.8e-60 203.1 0.1 1.3 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA_assoc_2 PF16193.5 KXH63481.1 - 7.5e-21 74.3 0.2 1.7e-20 73.2 0.2 1.6 1 0 0 1 1 1 1 AAA C-terminal domain AAA PF00004.29 KXH63481.1 - 2.7e-13 50.5 0.0 6.4e-13 49.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KXH63481.1 - 1.8e-08 34.3 0.0 3.7e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activat PF00158.26 KXH63481.1 - 3.6e-06 26.8 0.0 3.9e-05 23.4 0.0 2.1 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_16 PF13191.6 KXH63481.1 - 6.7e-06 26.6 0.9 0.0036 17.7 0.0 3.0 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 KXH63481.1 - 5.2e-05 23.3 0.1 0.0011 19.0 0.0 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 KXH63481.1 - 0.00023 20.6 0.1 0.14 11.6 0.0 2.2 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 KXH63481.1 - 0.00034 20.9 0.3 0.0027 18.0 0.1 2.4 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.6 KXH63481.1 - 0.0033 17.5 0.0 0.0056 16.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 KXH63481.1 - 0.0041 16.4 0.0 0.007 15.6 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain DUF815 PF05673.13 KXH63481.1 - 0.0062 15.7 0.0 0.01 15.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_19 PF13245.6 KXH63481.1 - 0.018 15.4 0.1 0.19 12.0 0.2 2.3 1 1 1 2 2 2 0 AAA domain ResIII PF04851.15 KXH63481.1 - 0.023 14.7 0.2 0.9 9.5 0.0 2.2 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit AAA_3 PF07726.11 KXH63481.1 - 0.042 13.7 0.0 0.21 11.4 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.6 KXH63481.1 - 0.043 13.9 0.0 0.079 13.1 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain DNA_pol3_delta2 PF13177.6 KXH63481.1 - 0.044 13.6 0.0 3.2 7.5 0.0 2.4 1 1 1 2 2 2 0 DNA polymerase III, delta subunit SKI PF01202.22 KXH63481.1 - 0.045 13.9 0.1 0.081 13.0 0.1 1.4 1 0 0 1 1 1 0 Shikimate kinase TRAF6_Z2 PF18048.1 KXH63481.1 - 0.078 13.1 0.2 0.13 12.4 0.2 1.4 1 0 0 1 1 1 0 TNF receptor-associated factor 6 zinc finger 2 AAA_24 PF13479.6 KXH63481.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain CPT PF07931.12 KXH63481.1 - 0.15 11.9 0.1 0.34 10.7 0.1 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein TniB PF05621.11 KXH63481.1 - 0.17 11.3 0.0 0.35 10.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein Fe-S_biosyn PF01521.20 KXH63482.1 - 4.5e-18 65.5 0.0 6.6e-18 64.9 0.0 1.3 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis Mucin PF01456.17 KXH63482.1 - 0.00016 21.7 19.2 0.00018 21.5 19.2 1.2 1 0 0 1 1 1 1 Mucin-like glycoprotein MAP65_ASE1 PF03999.12 KXH63482.1 - 0.005 15.6 6.0 0.0055 15.5 6.0 1.1 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) Suf PF05843.14 KXH63482.1 - 0.11 12.4 2.2 0.18 11.8 2.2 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Ndc1_Nup PF09531.10 KXH63482.1 - 0.19 10.4 5.8 0.2 10.3 5.8 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Pneumo_att_G PF05539.11 KXH63482.1 - 0.45 10.1 14.1 0.51 9.9 14.1 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G SOG2 PF10428.9 KXH63482.1 - 2 7.5 15.7 2.5 7.2 15.7 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein TFIIA PF03153.13 KXH63482.1 - 3.8 7.4 8.1 4.6 7.1 8.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ecl1 PF12855.7 KXH63482.1 - 4.4 8.4 21.8 6 8.0 21.8 1.1 1 0 0 1 1 1 0 ECL1/2/3 zinc binding proteins Dicty_REP PF05086.12 KXH63482.1 - 5.5 4.8 6.4 6.5 4.6 6.4 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Hamartin PF04388.12 KXH63482.1 - 7.9 5.0 13.1 9 4.8 13.1 1.0 1 0 0 1 1 1 0 Hamartin protein DUF1741 PF08427.10 KXH63483.1 - 3.2e-88 295.3 0.1 5.9e-88 294.4 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1741) Asp_protease_2 PF13650.6 KXH63484.1 - 3e-14 53.4 0.0 1.2e-08 35.5 0.0 3.6 3 1 0 3 3 3 2 Aspartyl protease gag-asp_proteas PF13975.6 KXH63484.1 - 3.8e-14 53.0 0.0 1.5e-09 38.2 0.0 3.8 3 1 0 3 3 3 2 gag-polyprotein putative aspartyl protease DnaJ PF00226.31 KXH63484.1 - 7.1e-08 32.5 0.6 3e-06 27.3 0.0 2.9 2 1 0 2 2 2 1 DnaJ domain Asp_protease PF09668.10 KXH63484.1 - 0.00073 19.3 0.0 0.062 13.1 0.0 2.8 2 2 0 2 2 2 1 Aspartyl protease HAUS2 PF15003.6 KXH63485.1 - 0.0028 17.4 0.6 0.0075 16.0 0.3 1.7 2 0 0 2 2 2 1 HAUS augmin-like complex subunit 2 UCR_Fe-S_N PF10399.9 KXH63485.1 - 0.29 10.5 2.2 1.2 8.6 2.5 1.8 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Cytotoxic PF09000.10 KXH63487.1 - 0.042 14.2 0.4 0.15 12.4 0.1 2.1 2 0 0 2 2 2 0 Cytotoxic Abhydrolase_1 PF00561.20 KXH63488.1 - 1.7e-17 63.9 0.2 2.8e-17 63.2 0.2 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXH63488.1 - 9.1e-15 55.9 0.1 1.1e-14 55.6 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXH63488.1 - 4e-06 26.3 0.0 6.9e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 EHN PF06441.12 KXH63488.1 - 0.023 15.1 0.3 0.046 14.1 0.3 1.5 1 0 0 1 1 1 0 Epoxide hydrolase N terminus AXE1 PF05448.12 KXH63488.1 - 0.14 10.8 0.0 0.2 10.3 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Pro_racemase PF05544.11 KXH63489.1 - 2.9e-57 194.2 4.9 6.5e-30 104.3 1.3 2.3 1 1 1 2 2 2 2 Proline racemase Bromodomain PF00439.25 KXH63490.1 - 2.1e-34 117.4 0.2 1.8e-18 66.4 0.1 2.9 3 0 0 3 3 3 2 Bromodomain BET PF17035.5 KXH63490.1 - 4.5e-14 52.4 1.5 1e-13 51.2 1.5 1.7 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation Prefoldin PF02996.17 KXH63490.1 - 0.069 13.1 2.3 3.1 7.7 0.1 3.0 2 0 0 2 2 2 0 Prefoldin subunit Utp12 PF04003.12 KXH63492.1 - 1.2e-18 67.4 0.4 8.7e-18 64.6 0.0 2.1 2 0 0 2 2 2 1 Dip2/Utp12 Family BSP_II PF05432.11 KXH63492.1 - 0.29 10.8 13.7 0.05 13.3 9.8 1.7 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) Esterase_phd PF10503.9 KXH63493.1 - 8.5e-24 84.3 0.3 1.1e-23 83.9 0.3 1.1 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 KXH63493.1 - 1.3e-07 31.3 0.1 1.9e-07 30.8 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 KXH63493.1 - 0.017 15.0 0.0 0.028 14.3 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF3328 PF11807.8 KXH63494.1 - 0.026 14.3 3.4 2.4 7.9 0.0 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF3328) Zn_clus PF00172.18 KXH63495.1 - 4e-05 23.7 13.8 8e-05 22.7 13.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain M20_dimer PF07687.14 KXH63496.1 - 2.4e-08 33.9 0.1 8.5e-08 32.1 0.1 2.0 1 1 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 KXH63496.1 - 3.3e-07 30.2 3.3 6.8e-07 29.2 3.1 1.6 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 CFEM PF05730.11 KXH63499.1 - 2.9e-05 24.1 5.4 5.5e-05 23.2 5.4 1.4 1 0 0 1 1 1 1 CFEM domain DUF2628 PF10947.8 KXH63499.1 - 0.0035 17.7 7.4 0.96 9.8 0.0 2.8 2 1 1 3 3 3 2 Protein of unknown function (DUF2628) Phage_holin_2_2 PF10746.9 KXH63499.1 - 1 9.1 7.7 1.2 8.8 0.5 3.2 4 0 0 4 4 4 0 Phage holin T7 family, holin superfamily II Methyltransf_25 PF13649.6 KXH63502.1 - 1.7e-14 54.3 0.0 3.6e-14 53.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH63502.1 - 1.2e-09 38.7 0.0 2.7e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXH63502.1 - 2e-07 31.0 0.0 5.8e-07 29.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH63502.1 - 4.2e-05 23.4 0.0 0.0001 22.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH63502.1 - 0.00041 21.0 0.0 0.00095 19.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXH63502.1 - 0.0013 18.1 0.0 0.0021 17.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.19 KXH63502.1 - 0.0089 16.1 0.0 0.018 15.1 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Dicty_REP PF05086.12 KXH63502.1 - 1.2 7.1 13.2 1.6 6.6 13.2 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein TFIIA PF03153.13 KXH63502.1 - 1.9 8.4 12.3 3.2 7.7 12.3 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit rve_3 PF13683.6 KXH63503.1 - 0.033 14.0 0.1 2.5 8.0 0.0 2.8 2 0 0 2 2 2 0 Integrase core domain Heme_oxygenase PF01126.20 KXH63503.1 - 0.053 13.3 0.1 0.088 12.6 0.1 1.3 1 0 0 1 1 1 0 Heme oxygenase DUF3287 PF11690.8 KXH63504.1 - 0.036 13.8 0.9 0.11 12.3 0.7 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3287) DUF1772 PF08592.11 KXH63508.1 - 1.9e-15 57.4 0.2 2.1e-15 57.2 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) Fungal_trans PF04082.18 KXH63509.1 - 4.5e-08 32.5 1.4 7.1e-08 31.8 1.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Filament_head PF04732.14 KXH63509.1 - 1.8 9.5 9.0 1e+03 0.7 9.0 2.4 1 1 0 1 1 1 0 Intermediate filament head (DNA binding) region NmrA PF05368.13 KXH63510.1 - 2.6e-21 76.3 0.0 3.4e-21 75.9 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXH63510.1 - 4.7e-13 49.4 0.5 1.3e-12 48.0 0.1 1.8 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 KXH63510.1 - 0.0001 21.9 0.2 0.005 16.3 0.3 2.5 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 KXH63510.1 - 0.00079 19.5 0.5 0.013 15.6 0.1 2.2 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase KR PF08659.10 KXH63510.1 - 0.0038 17.2 0.0 0.0074 16.2 0.0 1.5 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.17 KXH63510.1 - 0.004 17.7 0.6 0.012 16.2 0.1 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent MFS_1 PF07690.16 KXH63511.1 - 4.4e-34 117.9 35.0 1.2e-33 116.5 34.9 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KXH63511.1 - 0.00018 20.5 10.0 0.00018 20.5 10.0 1.4 1 1 0 1 1 1 1 MFS_1 like family 7tm_1 PF00001.21 KXH63512.1 - 0.00039 19.8 0.6 0.0008 18.8 0.6 1.5 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) ATP-synt_8 PF00895.20 KXH63512.1 - 8.6 6.9 5.4 6.4 7.3 0.5 2.6 2 0 0 2 2 2 0 ATP synthase protein 8 FAD_binding_3 PF01494.19 KXH63513.1 - 4.7e-17 62.3 0.0 5e-09 35.9 0.0 2.3 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KXH63513.1 - 0.00014 22.0 0.0 0.00029 21.0 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXH63513.1 - 0.00076 18.8 0.0 0.22 10.7 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXH63513.1 - 0.017 14.4 0.0 2.2 7.5 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXH63513.1 - 0.019 14.6 0.1 0.034 13.7 0.1 1.5 1 1 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.17 KXH63513.1 - 0.066 12.4 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.12 KXH63513.1 - 0.14 11.2 0.0 2 7.4 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein PKD_channel PF08016.12 KXH63514.1 - 0.14 10.8 4.8 0.066 11.9 0.5 2.0 1 1 0 2 2 2 0 Polycystin cation channel Acyl-CoA_dh_1 PF00441.24 KXH63515.1 - 9.1e-30 103.8 3.5 1.3e-29 103.4 3.5 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KXH63515.1 - 4.1e-24 85.4 0.2 3.3e-23 82.5 0.0 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KXH63515.1 - 1.1e-15 57.6 0.2 2e-07 31.1 0.1 2.3 2 0 0 2 2 2 2 Acyl-CoA dehydrogenase, middle domain Zn_clus PF00172.18 KXH63516.1 - 7.5e-07 29.2 7.5 1.1e-06 28.6 7.5 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Response_reg PF00072.24 KXH63517.1 - 8e-28 96.8 0.6 1.5e-27 96.0 0.6 1.4 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 KXH63517.1 - 1.3e-26 93.2 0.4 1.9e-24 86.3 0.1 3.2 2 1 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KXH63517.1 - 2.7e-14 52.9 0.0 6e-14 51.8 0.0 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 KXH63517.1 - 0.011 16.1 0.3 0.059 13.8 0.1 2.2 2 0 0 2 2 2 0 HAMP domain zf-CCHC PF00098.23 KXH63518.1 - 6.2e-42 139.8 79.5 1.6e-08 34.3 1.9 8.7 9 0 0 9 9 9 8 Zinc knuckle zf-CCHC_4 PF14392.6 KXH63518.1 - 1.1e-13 50.7 48.3 0.0065 16.2 0.2 8.2 8 0 0 8 8 8 7 Zinc knuckle zf-CCHC_2 PF13696.6 KXH63518.1 - 8.6e-11 41.4 62.2 0.0024 17.7 0.9 8.6 9 0 0 9 9 9 6 Zinc knuckle zf-CCHC_6 PF15288.6 KXH63518.1 - 1.2e-06 28.2 62.4 0.014 15.2 2.9 8.2 5 2 3 8 8 8 6 Zinc knuckle zf-CCHC_3 PF13917.6 KXH63518.1 - 7.4e-06 25.8 61.0 0.0072 16.3 0.9 8.5 2 2 7 9 9 9 6 Zinc knuckle DUF1929 PF09118.11 KXH63527.1 - 3.1e-22 78.7 0.0 7.5e-22 77.4 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) PAN_1 PF00024.26 KXH63527.1 - 2e-19 69.3 17.8 1.9e-06 27.7 2.8 3.3 3 0 0 3 3 3 3 PAN domain Kelch_6 PF13964.6 KXH63527.1 - 3.4e-15 55.7 1.7 0.0063 16.8 0.0 5.7 4 1 1 5 5 5 3 Kelch motif Kelch_1 PF01344.25 KXH63527.1 - 7.7e-12 44.6 3.4 3.2e-05 23.4 0.0 5.5 4 1 0 4 4 4 3 Kelch motif Kelch_4 PF13418.6 KXH63527.1 - 3.7e-10 39.6 7.5 0.17 11.9 0.3 5.8 4 1 0 4 4 4 4 Galactose oxidase, central domain Kelch_2 PF07646.15 KXH63527.1 - 2.3e-09 36.9 0.0 0.0027 17.6 0.0 4.8 4 0 0 4 4 4 2 Kelch motif PAN_4 PF14295.6 KXH63527.1 - 2.6e-08 33.6 16.5 0.02 14.8 0.6 3.7 3 0 0 3 3 3 3 PAN domain Glyoxal_oxid_N PF07250.11 KXH63527.1 - 5.4e-08 32.3 0.0 0.0061 15.8 0.0 3.2 2 1 1 3 3 3 2 Glyoxal oxidase N-terminus PAN_3 PF08277.12 KXH63527.1 - 0.0015 18.3 15.2 0.14 12.0 1.2 3.7 3 0 0 3 3 3 3 PAN-like domain Kelch_3 PF13415.6 KXH63527.1 - 0.073 13.4 0.5 22 5.5 0.0 4.0 4 0 0 4 4 3 0 Galactose oxidase, central domain MANEC PF07502.14 KXH63527.1 - 1.9 8.8 18.0 2.7 8.3 1.5 3.4 3 0 0 3 3 3 0 MANEC domain DUF5122 PF17164.4 KXH63527.1 - 3.4 8.0 12.5 46 4.4 0.4 5.1 5 0 0 5 5 5 0 Domain of unknown function (DUF5122) beta-propeller PAN_2 PF08276.11 KXH63527.1 - 6.7 6.9 25.0 0.72 10.0 2.7 3.6 3 0 0 3 3 3 0 PAN-like domain RRM_1 PF00076.22 KXH63532.1 - 9.9e-24 83.0 0.0 7.6e-11 41.7 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KXH63532.1 - 0.012 15.4 0.0 0.53 10.2 0.0 2.1 2 0 0 2 2 2 0 Occluded RNA-recognition motif PEX11 PF05648.14 KXH63533.1 - 6.9e-73 244.8 0.4 7.7e-73 244.6 0.4 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) FBPase PF00316.20 KXH63534.1 - 1.4e-72 243.2 0.1 1.9e-72 242.7 0.1 1.2 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain DUF1295 PF06966.12 KXH63535.1 - 3.4e-40 138.0 1.7 1.7e-38 132.5 1.7 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.16 KXH63535.1 - 0.0027 17.7 0.0 0.0065 16.5 0.0 1.7 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase GST_N PF02798.20 KXH63535.1 - 0.084 13.2 0.0 0.28 11.6 0.0 1.9 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain Tom6 PF17112.5 KXH63535.1 - 0.37 10.3 2.3 4.2 6.9 0.0 2.6 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom6, fungal Homoserine_dh PF00742.19 KXH63536.1 - 2.1e-52 177.5 0.0 2.7e-52 177.2 0.0 1.1 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 KXH63536.1 - 1.8e-17 64.1 0.0 3e-17 63.4 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain IGPS PF00218.21 KXH63536.1 - 0.13 11.4 0.1 0.23 10.6 0.1 1.3 1 0 0 1 1 1 0 Indole-3-glycerol phosphate synthase CIA30 PF08547.12 KXH63537.1 - 2.7e-37 128.2 0.0 3.4e-37 127.9 0.0 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) CBM_11 PF03425.13 KXH63537.1 - 0.031 14.2 0.0 0.042 13.7 0.0 1.2 1 0 0 1 1 1 0 Carbohydrate binding domain (family 11) bZIP_1 PF00170.21 KXH63538.1 - 0.0021 18.1 8.4 0.0033 17.5 8.4 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KXH63538.1 - 0.01 15.9 7.8 0.016 15.3 7.8 1.2 1 0 0 1 1 1 0 Basic region leucine zipper DUF4051 PF13260.6 KXH63551.1 - 0.033 13.9 2.4 5 6.9 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4051) F-box PF00646.33 KXH63551.1 - 0.073 13.0 4.8 5.6 7.0 0.0 3.3 3 0 0 3 3 3 0 F-box domain A2M_recep PF07677.14 KXH63551.1 - 0.19 12.5 0.0 4.2 8.1 0.0 2.3 1 1 1 2 2 2 0 A-macroglobulin receptor binding domain PilA4 PF18682.1 KXH63551.1 - 0.28 11.6 1.0 13 6.2 0.1 2.2 2 0 0 2 2 2 0 Pilin A4 DUF4164 PF13747.6 KXH63551.1 - 1.1 9.5 4.8 8.1 6.8 0.3 2.8 2 1 0 3 3 3 0 Domain of unknown function (DUF4164) EFF-AFF PF14884.6 KXH63552.1 - 0.12 10.5 0.0 0.19 9.8 0.0 1.2 1 1 0 1 1 1 0 Type I membrane glycoproteins cell-cell fusogen DUF4131 PF13567.6 KXH63552.1 - 1.5 8.4 4.9 2.7 7.6 1.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Patatin PF01734.22 KXH63557.1 - 5.4e-06 26.7 0.0 1.4e-05 25.4 0.0 1.5 2 0 0 2 2 2 1 Patatin-like phospholipase BacteriocIIc_cy PF12173.8 KXH63582.1 - 0.16 12.2 5.8 4.6 7.5 0.1 3.8 3 0 0 3 3 3 0 Bacteriocin class IIc cyclic gassericin A-like Attractin PF08037.11 KXH63582.1 - 0.24 11.4 4.8 0.77 9.8 4.8 1.9 1 0 0 1 1 1 0 Attractin family DSPc PF00782.20 KXH63595.1 - 1.4e-24 86.4 0.1 4.4e-23 81.6 0.1 2.2 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KXH63595.1 - 0.0039 16.8 0.0 0.0071 15.9 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 KXH63595.1 - 0.067 13.5 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 Rit1 DUSP-like domain Ufd2P_core PF10408.9 KXH63596.1 - 9.1e-215 715.0 10.9 1.2e-214 714.6 10.9 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 KXH63596.1 - 1.2e-25 89.5 1.1 3.7e-25 87.9 1.1 1.9 1 0 0 1 1 1 1 U-box domain zf-TRAF PF02176.18 KXH63597.1 - 1.1e-09 38.8 8.2 1.1e-09 38.8 8.2 4.1 2 1 2 4 4 3 2 TRAF-type zinc finger zf-C3HC4_3 PF13920.6 KXH63597.1 - 1.5e-07 31.1 5.0 1.5e-07 31.1 5.0 3.6 2 1 2 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXH63597.1 - 4.4e-06 26.4 10.1 4.4e-06 26.4 10.1 3.9 2 1 3 5 5 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXH63597.1 - 7.8e-06 26.1 9.3 7.8e-06 26.1 9.3 4.4 3 1 1 4 4 3 1 Ring finger domain zf-C3HC4 PF00097.25 KXH63597.1 - 1.4e-05 24.8 10.5 1.4e-05 24.8 10.5 3.5 2 1 1 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXH63597.1 - 2.6e-05 24.2 13.8 0.00011 22.1 13.0 2.6 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 KXH63597.1 - 2.9e-05 23.9 6.7 2.9e-05 23.9 6.7 3.6 2 2 1 3 3 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KXH63597.1 - 4.7e-05 23.2 8.3 4.7e-05 23.2 8.3 2.9 3 1 0 3 3 2 1 Prokaryotic RING finger family 4 zf-TRAF_2 PF15965.5 KXH63597.1 - 0.00016 22.1 30.5 0.0011 19.4 10.0 3.4 1 1 1 3 3 3 2 TRAF-like zinc-finger Sina PF03145.16 KXH63597.1 - 0.00058 19.9 9.2 0.0081 16.1 0.6 3.7 2 2 2 4 4 4 2 Seven in absentia protein family zf-C3HC4_4 PF15227.6 KXH63597.1 - 0.0009 19.4 6.6 0.0009 19.4 6.6 2.6 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 KXH63597.1 - 0.003 17.8 7.6 0.003 17.8 7.6 4.3 2 2 1 3 3 1 1 RING-H2 zinc finger domain U-box PF04564.15 KXH63597.1 - 0.017 15.3 1.0 0.063 13.5 0.5 2.3 2 0 0 2 2 1 0 U-box domain PRP1_N PF06424.12 KXH63597.1 - 0.066 13.6 1.0 0.14 12.5 1.0 1.5 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal Spc7 PF08317.11 KXH63597.1 - 0.099 11.5 5.6 1.2 7.9 1.5 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein DivIC PF04977.15 KXH63597.1 - 0.14 11.9 3.0 0.34 10.7 1.2 2.2 2 0 0 2 2 2 0 Septum formation initiator BLOC1_2 PF10046.9 KXH63597.1 - 0.15 12.4 3.0 1.5 9.2 0.1 2.6 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 zf_C2HC_14 PF18574.1 KXH63597.1 - 0.17 11.7 0.1 0.17 11.7 0.1 4.3 4 1 1 5 5 4 0 C2HC Zing finger domain zf-P11 PF03854.14 KXH63597.1 - 0.38 10.4 11.5 0.35 10.6 3.0 2.9 1 1 1 2 2 2 0 P-11 zinc finger zf_C2H2_13 PF18508.1 KXH63597.1 - 0.7 9.5 5.2 3.4 7.3 0.7 2.7 2 0 0 2 2 2 0 Zinc finger domain DUF16 PF01519.16 KXH63597.1 - 1.5 9.4 7.4 2.2 8.8 6.2 1.9 1 1 1 2 2 2 0 Protein of unknown function DUF16 GAS PF13851.6 KXH63597.1 - 1.5 8.1 8.5 0.37 10.1 1.9 2.4 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding SlyX PF04102.12 KXH63597.1 - 4 8.1 7.3 2 9.1 1.1 2.9 2 1 0 2 2 2 0 SlyX DUF2408 PF10303.9 KXH63597.1 - 4 8.0 7.1 0.92 10.1 2.2 2.2 2 1 1 3 3 2 0 Protein of unknown function (DUF2408) DUF848 PF05852.11 KXH63597.1 - 6.1 7.0 10.8 6.1 6.9 0.4 2.7 2 1 1 3 3 2 0 Gammaherpesvirus protein of unknown function (DUF848) Pyr_redox_2 PF07992.14 KXH63598.1 - 3.6e-13 49.4 0.0 2.8e-08 33.4 0.0 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXH63598.1 - 1.6e-10 40.8 0.0 3e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KXH63598.1 - 5.5e-08 31.7 0.0 9.9e-08 30.8 0.0 1.4 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KXH63598.1 - 3.9e-07 29.5 0.0 1.4e-06 27.7 0.0 1.8 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 KXH63598.1 - 2.9e-05 24.6 0.4 0.13 12.9 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXH63598.1 - 0.00021 21.5 0.1 0.00061 20.0 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KXH63598.1 - 0.0009 18.0 0.4 0.4 9.3 0.1 3.0 3 0 0 3 3 3 1 HI0933-like protein FAD_binding_3 PF01494.19 KXH63598.1 - 0.0034 16.7 0.5 0.0069 15.7 0.2 1.7 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 KXH63598.1 - 0.047 12.7 0.3 0.27 10.2 0.3 2.2 2 1 0 2 2 2 0 Lycopene cyclase protein 2-Hacid_dh_C PF02826.19 KXH63598.1 - 0.15 11.4 0.0 4.4 6.6 0.0 2.3 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain XdhC_C PF13478.6 KXH63598.1 - 0.18 12.3 0.0 1.2 9.6 0.0 2.1 2 0 0 2 2 2 0 XdhC Rossmann domain Zn_clus PF00172.18 KXH63611.1 - 4.9e-08 32.9 12.3 1.1e-07 31.9 12.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.22 KXH63631.1 - 4.7e-38 131.1 0.0 5.8e-38 130.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF4131 PF13567.6 KXH63631.1 - 0.0099 15.5 0.0 0.19 11.4 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4131) ApbA_C PF08546.11 KXH63631.1 - 0.14 12.4 0.1 0.37 11.0 0.1 1.6 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA C terminal Dioxygenase_C PF00775.21 KXH63632.1 - 5.9e-09 35.6 0.0 4.8e-08 32.7 0.0 2.2 1 1 0 1 1 1 1 Dioxygenase UxaC PF02614.14 KXH63632.1 - 0.14 11.0 0.0 0.19 10.5 0.0 1.1 1 0 0 1 1 1 0 Glucuronate isomerase HET PF06985.11 KXH63633.1 - 5e-24 85.3 0.0 8.9e-24 84.5 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF3787 PF12655.7 KXH63633.1 - 0.14 12.1 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3787) Glyco_hydro_5_C PF18564.1 KXH63634.1 - 2.5e-23 82.4 0.2 5.1e-23 81.4 0.2 1.6 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain Cellulase PF00150.18 KXH63634.1 - 3.6e-13 49.6 0.0 1.3e-05 24.8 0.0 3.0 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Aldo_ket_red PF00248.21 KXH63635.1 - 1.5e-41 142.6 0.1 2.2e-32 112.4 0.0 2.0 2 0 0 2 2 2 2 Aldo/keto reductase family DUF2110 PF09883.9 KXH63635.1 - 0.069 12.7 0.0 0.68 9.5 0.0 2.4 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2110) BPL_LplA_LipB PF03099.19 KXH63635.1 - 0.075 12.9 0.0 0.24 11.3 0.0 1.8 1 0 0 1 1 1 0 Biotin/lipoate A/B protein ligase family Fungal_trans PF04082.18 KXH63636.1 - 1.3e-09 37.5 0.6 2.3e-09 36.7 0.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH63636.1 - 2.9e-07 30.5 10.0 6.8e-07 29.3 10.0 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FRG2 PF15315.6 KXH63636.1 - 2.2 8.4 6.9 5.2 7.2 6.9 1.5 1 0 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 FAD_binding_3 PF01494.19 KXH63637.1 - 5.2e-71 239.7 0.1 6.4e-71 239.4 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 KXH63637.1 - 7.8e-08 32.5 0.0 2.9e-07 30.7 0.0 1.9 2 0 0 2 2 2 1 Phenol hydroxylase, C-terminal dimerisation domain DAO PF01266.24 KXH63637.1 - 5e-06 26.3 0.2 1.1e-05 25.2 0.2 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KXH63637.1 - 0.00014 21.2 0.1 0.00035 19.9 0.1 1.7 1 1 1 2 2 2 1 Thi4 family Pyr_redox_3 PF13738.6 KXH63637.1 - 0.00039 19.8 1.0 0.00079 18.8 0.3 1.8 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXH63637.1 - 0.00045 19.4 0.2 0.00073 18.7 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KXH63637.1 - 0.0011 18.3 0.4 0.0028 16.9 0.1 1.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KXH63637.1 - 0.0025 17.2 0.3 0.0053 16.2 0.3 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXH63637.1 - 0.0091 16.2 0.1 0.022 15.0 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain UDPG_MGDP_dh_N PF03721.14 KXH63637.1 - 0.022 14.3 0.0 0.049 13.2 0.0 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.16 KXH63637.1 - 0.023 14.3 0.1 0.06 13.0 0.1 1.7 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA HI0933_like PF03486.14 KXH63637.1 - 0.027 13.2 0.1 0.042 12.6 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Shikimate_DH PF01488.20 KXH63637.1 - 0.076 13.1 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase GIDA PF01134.22 KXH63637.1 - 0.085 11.9 1.1 0.17 10.9 0.3 1.8 1 1 1 2 2 2 0 Glucose inhibited division protein A Glu_dehyd_C PF16912.5 KXH63637.1 - 0.088 12.3 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus NAD_binding_7 PF13241.6 KXH63637.1 - 0.14 12.6 0.0 0.26 11.7 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Glyco_hydro_47 PF01532.20 KXH63638.1 - 3.1e-169 563.7 0.0 3.6e-169 563.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_76 PF03663.14 KXH63638.1 - 0.0027 17.3 0.0 2.6 7.5 0.0 2.5 3 0 0 3 3 3 2 Glycosyl hydrolase family 76 DOG1 PF14144.6 KXH63638.1 - 0.052 13.8 0.3 0.14 12.4 0.3 1.7 1 0 0 1 1 1 0 Seed dormancy control PGF-CTERM PF18204.1 KXH63639.1 - 3.4 7.8 4.9 5.5 7.1 4.9 1.3 1 0 0 1 1 1 0 PGF-CTERM motif DUF3433 PF11915.8 KXH63640.1 - 3.3e-17 62.7 4.2 9.3e-11 42.0 0.4 3.5 4 0 0 4 4 4 2 Protein of unknown function (DUF3433) Neur_chan_LBD PF02931.23 KXH63642.1 - 0.2 11.1 0.0 0.28 10.6 0.0 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel ligand binding domain Trypan_PARP PF05887.11 KXH63652.1 - 1.4 8.9 6.9 3.2 7.8 6.9 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Methyltransf_23 PF13489.6 KXH63653.1 - 1.3e-06 28.4 0.0 1.5e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH63653.1 - 0.012 16.3 0.0 0.022 15.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain FAD_binding_4 PF01565.23 KXH63659.1 - 2.9e-21 75.7 0.3 1.6e-16 60.3 0.3 2.5 2 0 0 2 2 2 2 FAD binding domain Na_Ca_ex PF01699.24 KXH63661.1 - 3.3e-34 118.0 35.1 2.9e-17 63.0 9.9 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Peptidase_C2 PF00648.21 KXH63662.1 - 1.8e-44 152.0 0.8 9e-43 146.4 0.8 2.5 1 1 0 1 1 1 1 Calpain family cysteine protease F-box-like PF12937.7 KXH63663.1 - 1.4e-06 28.1 1.0 3.5e-06 26.8 1.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXH63663.1 - 1.6e-05 24.6 0.5 1.6e-05 24.6 0.5 1.9 2 0 0 2 2 2 1 F-box domain Cep57_CLD_2 PF14197.6 KXH63664.1 - 0.00042 20.3 2.6 0.00063 19.8 2.6 1.2 1 0 0 1 1 1 1 Centrosome localisation domain of PPC89 KASH_CCD PF14662.6 KXH63664.1 - 0.0014 18.5 1.3 0.0023 17.8 1.3 1.3 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH GAS PF13851.6 KXH63664.1 - 0.0031 16.9 0.3 0.0043 16.4 0.3 1.1 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding ZapB PF06005.12 KXH63664.1 - 0.0034 17.8 4.7 0.073 13.5 4.3 2.1 1 1 1 2 2 2 2 Cell division protein ZapB DUF3450 PF11932.8 KXH63664.1 - 0.0036 16.6 0.6 0.0047 16.3 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) DivIC PF04977.15 KXH63664.1 - 0.0048 16.6 5.8 0.019 14.7 3.8 2.1 1 1 1 2 2 2 2 Septum formation initiator Taxilin PF09728.9 KXH63664.1 - 0.0062 15.7 0.1 0.0077 15.5 0.1 1.1 1 0 0 1 1 1 1 Myosin-like coiled-coil protein APG6_N PF17675.1 KXH63664.1 - 0.0079 16.7 0.8 0.01 16.4 0.8 1.2 1 0 0 1 1 1 1 Apg6 coiled-coil region ADIP PF11559.8 KXH63664.1 - 0.0094 16.1 3.8 0.014 15.5 3.8 1.1 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding DUF4795 PF16043.5 KXH63664.1 - 0.014 15.0 0.1 0.021 14.4 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) JIP_LZII PF16471.5 KXH63664.1 - 0.018 15.2 0.3 0.037 14.2 0.3 1.5 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II Spc7 PF08317.11 KXH63664.1 - 0.023 13.6 2.7 0.031 13.2 2.7 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein GIT_CC PF16559.5 KXH63664.1 - 0.024 14.5 1.7 1.3 8.9 0.3 2.3 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor TMF_TATA_bd PF12325.8 KXH63664.1 - 0.03 14.5 4.0 0.046 13.9 4.0 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding TPR_MLP1_2 PF07926.12 KXH63664.1 - 0.038 14.0 3.7 0.058 13.5 3.7 1.3 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF4686 PF15742.5 KXH63664.1 - 0.052 12.7 2.9 0.067 12.3 2.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4686) BRE1 PF08647.11 KXH63664.1 - 0.056 13.5 4.7 0.079 13.0 4.7 1.2 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase FPP PF05911.11 KXH63664.1 - 0.056 11.6 1.5 0.074 11.2 1.5 1.1 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil HALZ PF02183.18 KXH63664.1 - 0.069 13.4 7.4 0.11 12.7 0.8 2.4 1 1 1 2 2 2 0 Homeobox associated leucine zipper Spc24 PF08286.11 KXH63664.1 - 0.1 12.9 0.5 0.18 12.0 0.5 1.4 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 DUF724 PF05266.14 KXH63664.1 - 0.11 12.3 1.8 0.16 11.8 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) TSC22 PF01166.18 KXH63664.1 - 0.11 12.8 3.0 3 8.2 0.2 2.3 2 0 0 2 2 2 0 TSC-22/dip/bun family HOOK PF05622.12 KXH63664.1 - 0.11 10.6 3.7 0.15 10.2 3.7 1.1 1 0 0 1 1 1 0 HOOK protein DUF3552 PF12072.8 KXH63664.1 - 0.21 11.0 6.0 0.28 10.6 6.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DUF4337 PF14235.6 KXH63664.1 - 0.38 10.8 0.9 0.53 10.4 0.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF3287 PF11690.8 KXH63664.1 - 1.4 8.6 4.7 3.3 7.5 4.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3287) SlyX PF04102.12 KXH63664.1 - 4.2 8.0 5.1 33 5.2 5.0 2.1 1 1 0 1 1 1 0 SlyX dsrm PF00035.26 KXH63665.1 - 3.9e-05 24.3 0.0 6e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Double-stranded RNA binding motif DND1_DSRM PF14709.7 KXH63665.1 - 0.00084 19.6 0.1 0.0034 17.6 0.1 1.9 1 1 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 DUF2850 PF11012.8 KXH63665.1 - 0.12 12.7 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2850) Pkinase_fungal PF17667.1 KXH63667.1 - 1.3e-133 445.8 0.0 2.3e-133 445.0 0.0 1.4 2 0 0 2 2 2 1 Fungal protein kinase Pkinase PF00069.25 KXH63667.1 - 0.00097 18.6 0.0 0.0019 17.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KXH63667.1 - 0.0051 16.8 0.2 0.33 10.8 0.1 3.2 3 1 1 4 4 4 1 Phosphotransferase enzyme family BTB PF00651.31 KXH63668.1 - 0.039 14.2 0.0 0.077 13.2 0.0 1.4 1 0 0 1 1 1 0 BTB/POZ domain Vta1 PF04652.16 KXH63669.1 - 0.14 12.1 0.0 0.17 11.9 0.0 1.1 1 0 0 1 1 1 0 Vta1 like TetR_C_11 PF16859.5 KXH63670.1 - 0.17 12.2 1.4 18 5.7 0.1 2.5 2 1 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain TetR_C_28 PF17937.1 KXH63670.1 - 3.2 8.3 6.2 4.5 7.8 0.1 2.7 2 1 1 3 3 3 0 Tetracyclin repressor-like, C-terminal domain GAS PF13851.6 KXH63671.1 - 0.00024 20.5 11.4 0.00037 19.9 11.4 1.2 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding PSII_Pbs27 PF13326.6 KXH63671.1 - 0.01 16.2 0.4 0.084 13.2 0.2 2.6 2 1 0 2 2 2 0 Photosystem II Pbs27 Tropomyosin_1 PF12718.7 KXH63671.1 - 0.052 13.7 7.7 0.11 12.6 7.7 1.6 1 0 0 1 1 1 0 Tropomyosin like RE_Bsp6I PF09504.10 KXH63671.1 - 0.098 12.3 0.3 0.17 11.5 0.3 1.4 1 0 0 1 1 1 0 Bsp6I restriction endonuclease Rsbr_N PF08678.10 KXH63671.1 - 0.16 12.1 2.3 0.35 11.0 2.3 1.6 1 0 0 1 1 1 0 Rsbr N terminal DivIC PF04977.15 KXH63671.1 - 0.28 11.0 5.4 0.85 9.4 5.4 1.9 1 0 0 1 1 1 0 Septum formation initiator DUF445 PF04286.12 KXH63671.1 - 0.3 10.8 3.1 0.48 10.2 3.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) bZIP_1 PF00170.21 KXH63671.1 - 0.54 10.4 7.7 0.12 12.5 2.5 2.3 2 1 1 3 3 3 0 bZIP transcription factor GIT_CC PF16559.5 KXH63671.1 - 0.7 9.8 5.2 2.1 8.3 5.2 1.7 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor RD3 PF14473.6 KXH63671.1 - 1.1 9.1 7.6 2.8 7.8 5.0 2.4 2 0 0 2 2 2 0 RD3 protein ZapB PF06005.12 KXH63671.1 - 6.3 7.3 13.5 3.9 8.0 9.1 2.4 1 1 1 2 2 2 0 Cell division protein ZapB TSC22 PF01166.18 KXH63671.1 - 7.5 6.9 11.1 1.6 9.1 3.8 3.3 2 1 1 3 3 3 0 TSC-22/dip/bun family Cytotoxic PF09000.10 KXH63709.1 - 0.0058 16.9 0.0 0.013 15.8 0.0 1.6 1 0 0 1 1 1 1 Cytotoxic AMPK1_CBM PF16561.5 KXH63710.1 - 1.5e-05 25.1 0.0 3.3e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase HAMP PF00672.25 KXH63710.1 - 0.039 14.3 0.3 15 6.0 0.0 2.6 2 0 0 2 2 2 0 HAMP domain Iwr1 PF08574.10 KXH63711.1 - 3.3e-06 28.0 1.3 3.3e-06 28.0 1.3 4.3 3 1 1 4 4 4 2 Transcription factor Iwr1 FAD_binding_2 PF00890.24 KXH63729.1 - 9e-83 278.7 0.7 1.1e-82 278.4 0.7 1.1 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.28 KXH63729.1 - 2e-21 75.9 0.0 1.5e-20 73.1 0.0 2.5 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.24 KXH63729.1 - 1.1e-13 51.5 0.2 2e-13 50.7 0.2 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KXH63729.1 - 5.7e-10 39.1 0.9 3.5e-09 36.5 0.9 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXH63729.1 - 1.4e-07 31.6 2.7 6.3e-07 29.5 0.8 2.8 2 1 1 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXH63729.1 - 9.2e-07 28.4 0.2 1.4e-05 24.5 0.1 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXH63729.1 - 2.6e-05 23.7 0.0 0.18 11.1 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KXH63729.1 - 5.9e-05 22.5 0.3 0.00013 21.4 0.4 1.4 1 1 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KXH63729.1 - 0.00012 20.9 4.1 0.011 14.5 0.5 3.3 3 1 0 3 3 3 1 HI0933-like protein Thi4 PF01946.17 KXH63729.1 - 0.0009 18.6 1.9 0.062 12.5 0.9 2.4 2 0 0 2 2 2 1 Thi4 family Amino_oxidase PF01593.24 KXH63729.1 - 0.002 17.5 0.7 0.26 10.5 0.2 2.9 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase GIDA PF01134.22 KXH63729.1 - 0.0087 15.2 3.7 0.17 11.0 1.5 2.3 2 0 0 2 2 2 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 KXH63729.1 - 0.042 13.1 0.8 0.077 12.3 0.8 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 KXH63729.1 - 0.084 13.4 2.3 2.1 9.0 0.5 2.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Sin3a_C PF16879.5 KXH63730.1 - 2.7e-75 253.7 0.9 2.7e-75 253.7 0.9 2.5 4 0 0 4 4 4 1 C-terminal domain of Sin3a protein PAH PF02671.21 KXH63730.1 - 2.1e-44 149.4 8.6 8.4e-18 64.2 2.8 4.4 3 1 1 4 4 4 3 Paired amphipathic helix repeat Sin3_corepress PF08295.12 KXH63730.1 - 8.1e-39 131.7 0.0 1.9e-38 130.5 0.0 1.7 1 0 0 1 1 1 1 Sin3 family co-repressor DUF2764 PF10962.8 KXH63730.1 - 0.1 12.1 0.2 0.41 10.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2764) TSP_NTD PF17804.1 KXH63730.1 - 3.7 7.8 12.9 0.54 10.5 0.4 3.4 3 1 0 3 3 3 0 Tail specific protease N-terminal domain Herpes_U30 PF04523.13 KXH63732.1 - 0.046 11.6 0.2 0.067 11.1 0.2 1.2 1 0 0 1 1 1 0 Herpes virus tegument protein U30 TFIIA PF03153.13 KXH63732.1 - 0.1 12.6 17.6 0.14 12.2 17.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PPP4R2 PF09184.11 KXH63732.1 - 1.5 8.4 19.9 2.4 7.7 19.9 1.3 1 0 0 1 1 1 0 PPP4R2 zf-HYPF PF07503.12 KXH63740.1 - 0.03 14.1 1.8 0.082 12.7 1.8 1.8 1 0 0 1 1 1 0 HypF finger FYDLN_acid PF09538.10 KXH63740.1 - 0.12 13.1 0.1 0.12 13.1 0.1 3.2 4 0 0 4 4 4 0 Protein of unknown function (FYDLN_acid) APG5 PF04106.12 KXH63741.1 - 1e-42 146.3 0.0 4.8e-42 144.1 0.0 1.9 1 1 0 1 1 1 1 Autophagy protein Apg5 Methyltransf_3 PF01596.17 KXH63794.1 - 1.5e-29 102.7 0.0 2.4e-29 102.0 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase PCMT PF01135.19 KXH63794.1 - 2.6e-10 40.4 0.0 3.4e-10 40.0 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_24 PF13578.6 KXH63794.1 - 3.3e-09 37.7 0.0 7.2e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH63794.1 - 1.9e-08 34.3 0.0 2.8e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH63794.1 - 5e-06 27.1 0.0 8.3e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KXH63794.1 - 0.015 14.8 0.0 0.025 14.1 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_12 PF08242.12 KXH63794.1 - 0.034 14.9 0.0 0.055 14.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Fibrillarin PF01269.17 KXH63794.1 - 0.094 11.8 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Fibrillarin CAP_N PF01213.19 KXH63795.1 - 2.7 7.4 4.7 3.9 6.9 4.7 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Methyltransf_23 PF13489.6 KXH63797.1 - 3.2e-25 88.9 0.0 4.7e-25 88.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH63797.1 - 4.4e-11 43.3 0.0 1.2e-10 42.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH63797.1 - 2.2e-09 37.3 0.0 0.0012 18.7 0.0 2.1 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 KXH63797.1 - 3.1e-08 34.1 0.0 5.6e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH63797.1 - 1.7e-07 31.9 0.0 1.6e-06 28.7 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXH63797.1 - 0.0081 15.7 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.19 KXH63797.1 - 0.027 14.6 0.0 0.046 13.8 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase PCMT PF01135.19 KXH63797.1 - 0.032 14.0 0.0 0.049 13.4 0.0 1.4 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 KXH63797.1 - 0.085 12.2 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Maf1 PF09174.10 KXH63798.1 - 7.2e-56 189.1 0.0 1.4e-55 188.2 0.0 1.5 1 0 0 1 1 1 1 Maf1 regulator Clat_adaptor_s PF01217.20 KXH63798.1 - 5.3e-50 169.0 1.5 8.1e-50 168.5 1.5 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Aldo_ket_red PF00248.21 KXH63799.1 - 1.2e-08 34.5 0.0 1.7e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family ECR1_N PF14382.6 KXH63800.1 - 8e-18 64.0 1.4 1.6e-17 63.0 1.4 1.5 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region KH_6 PF15985.5 KXH63800.1 - 0.00046 20.5 0.1 0.00091 19.5 0.1 1.5 1 0 0 1 1 1 1 KH domain EXOSC1 PF10447.9 KXH63800.1 - 0.061 13.9 4.4 0.62 10.7 0.1 3.5 3 1 1 4 4 4 0 Exosome component EXOSC1/CSL4 DUF4536 PF15055.6 KXH63801.1 - 1.1e-05 25.6 5.0 2.7e-05 24.3 5.0 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4536) Adap_comp_sub PF00928.21 KXH63802.1 - 1.6e-70 237.5 0.0 2e-70 237.2 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KXH63802.1 - 3e-05 24.0 0.0 4.6e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Acyl_transf_1 PF00698.21 KXH63803.1 - 3.7e-18 66.1 0.0 7.4e-13 48.7 0.0 2.2 2 0 0 2 2 2 2 Acyl transferase domain DUF2458 PF10454.9 KXH63803.1 - 0.16 11.6 0.0 0.25 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2458) AFG1_ATPase PF03969.16 KXH63805.1 - 4.9e-54 183.6 0.0 3.6e-27 95.2 0.0 4.7 4 1 1 5 5 5 4 AFG1-like ATPase AAA_16 PF13191.6 KXH63805.1 - 3.1e-05 24.4 1.7 0.0032 17.9 0.2 3.0 2 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 KXH63805.1 - 0.00024 21.1 0.0 0.00058 19.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KXH63805.1 - 0.0024 18.1 0.0 0.0077 16.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 KXH63805.1 - 0.014 15.8 0.0 0.03 14.8 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Bac_DnaA PF00308.18 KXH63805.1 - 0.033 14.0 0.0 0.45 10.3 0.0 2.3 2 0 0 2 2 2 0 Bacterial dnaA protein AAA_29 PF13555.6 KXH63805.1 - 0.051 13.3 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 KXH63805.1 - 0.053 13.5 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KXH63805.1 - 0.11 12.4 0.0 0.36 10.7 0.0 1.9 2 0 0 2 2 2 0 NACHT domain TsaE PF02367.17 KXH63805.1 - 0.13 12.3 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 KXH63805.1 - 0.14 12.7 0.2 4.1 7.9 0.1 2.5 1 1 1 2 2 2 0 ABC transporter Nucleoporin_C PF03177.14 KXH63806.1 - 1.7e-194 648.0 18.1 2.1e-194 647.7 18.1 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.11 KXH63806.1 - 1.4e-84 284.3 0.0 1.8e-84 284.0 0.0 1.1 1 0 0 1 1 1 1 Nup133 N terminal like Pkinase PF00069.25 KXH63807.1 - 4.9e-27 95.0 0.0 6.3e-27 94.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXH63807.1 - 2.6e-14 53.2 0.0 3.3e-14 52.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXH63807.1 - 1.1e-06 27.7 0.0 1.5e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Peptidase_M44 PF03410.13 KXH63807.1 - 0.17 10.4 0.0 0.24 9.9 0.0 1.1 1 0 0 1 1 1 0 Metallopeptidase from vaccinia pox Fungal_trans PF04082.18 KXH63808.1 - 1.6e-12 47.0 0.0 2.6e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH63808.1 - 2e-05 24.6 7.0 3.6e-05 23.8 7.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Hexapep_2 PF14602.6 KXH63809.1 - 6.1e-15 54.7 23.4 7.6e-10 38.4 3.7 3.2 4 0 0 4 4 4 2 Hexapeptide repeat of succinyl-transferase Mac PF12464.8 KXH63809.1 - 2.3e-13 50.1 0.4 7.8e-13 48.5 0.0 2.0 2 0 0 2 2 2 1 Maltose acetyltransferase Hexapep PF00132.24 KXH63809.1 - 3e-13 48.9 20.3 3.8e-09 35.9 3.2 4.0 4 1 0 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Zn_clus PF00172.18 KXH63809.1 - 1.2e-09 38.1 8.6 2.3e-09 37.2 8.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SANT_DAMP1_like PF16282.5 KXH63810.1 - 4.2e-31 107.0 0.2 9e-31 105.9 0.2 1.6 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 DUF809 PF05663.11 KXH63810.1 - 0.00016 21.8 0.1 0.00056 20.1 0.1 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF809) EMP24_GP25L PF01105.24 KXH63811.1 - 6.5e-53 179.4 0.0 7.3e-53 179.2 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD HXXSHH PF07586.11 KXH63811.1 - 0.095 12.3 0.2 0.15 11.7 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) Thymosin PF01290.20 KXH63811.1 - 0.12 12.1 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Thymosin beta-4 family PPR_2 PF13041.6 KXH63812.1 - 2.6e-20 72.3 0.0 1.6e-06 28.2 0.0 5.4 4 1 1 5 5 5 4 PPR repeat family PPR_1 PF12854.7 KXH63812.1 - 2.3e-17 62.4 0.0 2.1e-05 24.1 0.0 5.5 5 0 0 5 5 5 3 PPR repeat PPR_3 PF13812.6 KXH63812.1 - 1.1e-11 44.6 0.0 4.4e-05 23.5 0.0 3.3 3 0 0 3 3 3 2 Pentatricopeptide repeat domain PPR PF01535.20 KXH63812.1 - 6.8e-10 38.5 1.3 0.12 12.7 0.0 5.7 5 2 0 5 5 5 2 PPR repeat PPR_long PF17177.4 KXH63812.1 - 2.3e-05 23.9 0.0 0.033 13.6 0.0 2.8 3 0 0 3 3 3 2 Pentacotripeptide-repeat region of PRORP DUF5039 PF16442.5 KXH63812.1 - 0.035 13.6 0.3 0.072 12.6 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5039) cwf18 PF08315.12 KXH63813.1 - 1.1e-45 155.6 7.3 1.1e-45 155.6 7.3 1.6 2 0 0 2 2 2 1 cwf18 pre-mRNA splicing factor TraI PF07057.11 KXH63813.1 - 0.082 13.0 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 DNA helicase TraI Pam16 PF03656.13 KXH63813.1 - 0.18 11.8 2.6 0.31 11.1 1.5 1.9 1 1 1 2 2 2 0 Pam16 zf-CCHC_3 PF13917.6 KXH63814.1 - 1.7e-13 50.2 6.2 4.1e-10 39.4 1.1 2.7 2 0 0 2 2 2 2 Zinc knuckle SUZ PF12752.7 KXH63815.1 - 8.2e-16 58.5 4.8 8.2e-16 58.5 4.8 3.3 4 0 0 4 4 4 1 SUZ domain R3H PF01424.22 KXH63815.1 - 2.8e-08 33.6 0.0 7.1e-08 32.3 0.0 1.7 1 0 0 1 1 1 1 R3H domain MitMem_reg PF13012.6 KXH63816.1 - 8e-18 64.9 0.3 1.7e-17 63.8 0.1 1.7 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function JAB PF01398.21 KXH63816.1 - 3.1e-15 56.2 0.0 5.5e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease UTP25 PF06862.12 KXH63817.1 - 8e-197 654.7 0.3 9.9e-197 654.4 0.3 1.1 1 0 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Pox_Ag35 PF03286.14 KXH63817.1 - 2.9 7.6 12.2 5.4 6.8 12.2 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Nop14 PF04147.12 KXH63817.1 - 6.6 4.8 18.2 9.1 4.4 18.2 1.2 1 0 0 1 1 1 0 Nop14-like family Ribosomal_L17 PF01196.19 KXH63818.1 - 1.9e-32 112.0 0.1 1.9e-32 112.0 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein L17 SBDS PF01172.18 KXH63818.1 - 0.04 14.0 0.7 0.07 13.2 0.2 1.6 2 0 0 2 2 2 0 Shwachman-Bodian-Diamond syndrome (SBDS) protein Mrpl_C PF18502.1 KXH63818.1 - 0.21 11.9 2.0 0.2 12.0 0.6 1.7 2 0 0 2 2 2 0 54S ribosomal protein L8 C-terminal domain AIM5 PF17050.5 KXH63819.1 - 1.3e-18 67.6 3.3 1.3e-18 67.6 3.3 2.2 2 0 0 2 2 2 1 Altered inheritance of mitochondria 5 Borrelia_P83 PF05262.11 KXH63819.1 - 0.061 11.8 9.7 0.072 11.6 9.7 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Remorin_N PF03766.13 KXH63820.1 - 0.17 12.0 0.7 16 5.6 0.0 2.3 2 0 0 2 2 2 0 Remorin, N-terminal region Aldedh PF00171.22 KXH63821.1 - 1.3e-82 277.8 0.0 1.5e-82 277.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family MRP-S28 PF10213.9 KXH63822.1 - 1.5e-48 164.4 0.8 3.1e-48 163.4 0.8 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein DUF1682 PF07946.14 KXH63822.1 - 0.05 12.8 3.9 0.099 11.8 3.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) CDC13_N PF16853.5 KXH63822.1 - 0.17 11.4 0.3 0.34 10.4 0.3 1.4 1 0 0 1 1 1 0 Cell division control protein 13 N-terminus Ank_2 PF12796.7 KXH63823.1 - 2.1e-57 191.7 6.3 9e-12 45.4 0.1 7.2 3 2 2 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXH63823.1 - 7.6e-43 144.4 2.6 5.4e-07 30.0 0.0 9.6 5 3 4 10 10 10 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXH63823.1 - 9.7e-35 114.7 2.9 0.0019 18.5 0.0 11.5 11 0 0 11 11 10 7 Ankyrin repeat Ank PF00023.30 KXH63823.1 - 1.2e-32 110.8 15.1 0.00016 21.9 0.0 11.5 13 0 0 13 13 13 7 Ankyrin repeat Ank_5 PF13857.6 KXH63823.1 - 5.6e-29 99.8 14.7 1.5e-07 31.6 0.4 9.5 4 2 5 10 10 10 6 Ankyrin repeats (many copies) Sigma70_ner PF04546.13 KXH63823.1 - 7.2e-06 26.0 3.9 0.021 14.7 0.0 3.1 2 1 0 2 2 2 1 Sigma-70, non-essential region Abhydrolase_6 PF12697.7 KXH63823.1 - 3.8e-05 24.4 0.0 3.8e-05 24.4 0.0 2.8 2 1 1 3 3 1 1 Alpha/beta hydrolase family AAA_16 PF13191.6 KXH63823.1 - 3.8e-05 24.1 1.0 0.00017 22.0 0.1 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KXH63823.1 - 0.00018 21.8 0.0 0.00061 20.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain DUF676 PF05057.14 KXH63823.1 - 0.00077 19.0 0.0 0.0016 18.0 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 KXH63823.1 - 0.0063 15.8 0.0 0.015 14.6 0.0 1.6 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 KXH63823.1 - 0.011 15.5 0.0 0.023 14.4 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein Cutinase PF01083.22 KXH63823.1 - 0.011 15.7 0.4 0.063 13.2 0.0 2.3 3 0 0 3 3 3 0 Cutinase Thioesterase PF00975.20 KXH63823.1 - 0.057 13.5 0.0 1.1 9.3 0.0 2.7 2 0 0 2 2 2 0 Thioesterase domain Lipase_3 PF01764.25 KXH63823.1 - 0.091 12.6 0.0 0.24 11.2 0.0 1.7 1 0 0 1 1 1 0 Lipase (class 3) CDC45 PF02724.14 KXH63823.1 - 1.1 7.5 18.0 0.35 9.1 4.8 2.3 2 0 0 2 2 2 0 CDC45-like protein SDA1 PF05285.12 KXH63823.1 - 8.5 5.7 26.3 1.2 8.4 10.7 2.4 2 0 0 2 2 2 0 SDA1 Glyco_tran_28_C PF04101.16 KXH63825.1 - 1.7e-18 67.2 0.0 3.7e-18 66.1 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain WD40 PF00400.32 KXH63826.1 - 1.2e-28 98.7 36.7 7.5e-05 23.4 0.1 10.8 11 0 0 11 11 11 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXH63826.1 - 3.5e-15 56.1 6.7 0.00034 20.8 0.1 6.5 5 2 2 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KXH63826.1 - 1.2e-05 25.1 0.5 5.9 7.0 0.0 4.4 4 0 0 4 4 4 3 WD40-like Beta Propeller Repeat Nbas_N PF15492.6 KXH63826.1 - 0.0001 21.8 0.7 0.79 9.0 0.1 3.5 3 0 0 3 3 3 2 Neuroblastoma-amplified sequence, N terminal Ge1_WD40 PF16529.5 KXH63826.1 - 0.00095 18.2 4.6 0.25 10.3 0.2 4.2 3 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein CPSF_A PF03178.15 KXH63826.1 - 0.003 16.9 0.0 0.016 14.5 0.0 2.0 2 0 0 2 2 2 1 CPSF A subunit region SNF2_N PF00176.23 KXH63827.1 - 9.7e-77 258.0 0.1 2e-76 257.0 0.1 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 KXH63827.1 - 2.4e-42 143.5 1.5 2.4e-42 143.5 1.5 2.6 2 0 0 2 2 2 1 SLIDE HAND PF09110.11 KXH63827.1 - 9.4e-34 116.5 6.1 9.4e-34 116.5 6.1 4.4 4 0 0 4 4 4 1 HAND Helicase_C PF00271.31 KXH63827.1 - 2.8e-18 66.3 0.6 1.4e-17 64.0 0.0 2.6 3 0 0 3 3 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXH63827.1 - 5.3e-11 42.8 0.1 3.9e-10 40.0 0.0 2.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Myb_DNA-binding PF00249.31 KXH63827.1 - 4.1e-05 23.7 0.0 0.071 13.3 0.0 3.0 2 0 0 2 2 2 2 Myb-like DNA-binding domain HDA2-3 PF11496.8 KXH63827.1 - 0.00013 21.3 0.0 0.00048 19.4 0.0 2.0 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 KXH63827.1 - 0.00037 20.3 0.0 0.0017 18.1 0.0 2.2 3 0 0 3 3 3 1 DEAD/DEAH box helicase DUF1086 PF06461.11 KXH63827.1 - 0.0034 17.2 0.1 0.0084 16.0 0.1 1.6 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1086) Occludin_ELL PF07303.13 KXH63827.1 - 0.077 13.7 4.5 0.29 11.9 4.5 2.0 1 0 0 1 1 1 0 Occludin homology domain Tn7_Tnp_TnsA_C PF08721.11 KXH63827.1 - 0.77 10.4 3.9 5.4 7.7 0.1 3.4 3 0 0 3 3 3 0 TnsA endonuclease C terminal DUF4588 PF15251.6 KXH63828.1 - 3.3e-08 33.6 1.7 6.4e-08 32.7 1.7 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4588) Cytochrom_B562 PF07361.11 KXH63828.1 - 0.036 14.7 0.0 0.058 14.0 0.0 1.4 1 0 0 1 1 1 0 Cytochrome b562 WD40 PF00400.32 KXH63829.1 - 7.5e-23 80.4 0.2 8.7e-08 32.7 0.2 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXH63829.1 - 5.7e-13 49.0 0.0 0.0083 16.4 0.0 4.9 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KXH63829.1 - 0.0026 17.7 0.1 3.3 7.5 0.0 2.8 2 2 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KXH63829.1 - 0.0046 16.3 0.0 0.14 11.4 0.0 2.7 1 1 1 2 2 2 1 WD40-like domain Coatomer_WDAD PF04053.14 KXH63829.1 - 0.014 14.5 0.1 0.16 10.9 0.0 2.0 1 1 0 2 2 2 0 Coatomer WD associated region PQQ_2 PF13360.6 KXH63829.1 - 0.017 14.7 0.0 0.38 10.3 0.0 2.3 1 1 0 1 1 1 0 PQQ-like domain Nup160 PF11715.8 KXH63829.1 - 0.036 12.7 0.0 0.048 12.3 0.0 1.2 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 KXH63829.1 - 0.046 12.5 0.0 0.058 12.1 0.0 1.2 1 0 0 1 1 1 0 Nup133 N terminal like FTHFS PF01268.19 KXH63830.1 - 4.7e-254 843.7 0.1 6.7e-254 843.2 0.1 1.2 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.19 KXH63830.1 - 8.9e-67 223.4 2.8 9.9e-67 223.2 0.7 2.0 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 KXH63830.1 - 1.5e-38 131.6 0.6 3.5e-38 130.4 0.6 1.7 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Glyco_trans_1_4 PF13692.6 KXH63830.1 - 0.038 14.4 0.0 0.19 12.1 0.1 2.2 2 0 0 2 2 2 0 Glycosyl transferases group 1 OCD_Mu_crystall PF02423.15 KXH63830.1 - 0.065 12.2 0.6 0.12 11.2 0.1 1.6 2 0 0 2 2 2 0 Ornithine cyclodeaminase/mu-crystallin family GTP_EFTU PF00009.27 KXH63830.1 - 0.16 11.5 0.0 0.42 10.1 0.0 1.7 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain NAD_binding_6 PF08030.12 KXH63831.1 - 1.4e-21 77.2 0.0 2e-21 76.7 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 KXH63831.1 - 8.9e-13 48.4 13.1 8.9e-13 48.4 13.1 1.8 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KXH63831.1 - 8.8e-08 32.2 0.0 2.1e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain S19 PF06756.11 KXH63831.1 - 0.079 12.9 0.3 0.22 11.5 0.0 1.8 2 0 0 2 2 2 0 Chorion protein S19 C-terminal Peptidase_M15_2 PF05951.13 KXH63832.1 - 0.046 13.4 0.1 0.13 11.9 0.1 1.8 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF882) Rhomboid PF01694.22 KXH63834.1 - 6.2e-18 65.2 4.6 1.2e-17 64.3 4.6 1.4 1 0 0 1 1 1 1 Rhomboid family RTA1 PF04479.13 KXH63835.1 - 1.4e-27 96.7 5.9 1.8e-27 96.3 5.9 1.1 1 0 0 1 1 1 1 RTA1 like protein PGAP1 PF07819.13 KXH63836.1 - 1.4e-06 28.2 0.1 2.4e-06 27.5 0.1 1.3 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.14 KXH63836.1 - 5.9e-06 25.9 0.0 7.7e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 KXH63836.1 - 8.9e-05 22.4 0.0 0.00015 21.7 0.0 1.4 2 0 0 2 2 2 1 Palmitoyl protein thioesterase Abhydrolase_6 PF12697.7 KXH63836.1 - 0.00037 21.2 0.2 0.00043 21.0 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family LCAT PF02450.15 KXH63836.1 - 0.00077 18.7 0.0 0.0011 18.2 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF915 PF06028.11 KXH63836.1 - 0.021 14.2 0.0 0.064 12.6 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Ser_hydrolase PF06821.13 KXH63836.1 - 0.031 14.2 0.0 0.05 13.4 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase Lipase_2 PF01674.18 KXH63836.1 - 0.057 12.9 0.0 0.13 11.8 0.1 1.5 2 0 0 2 2 2 0 Lipase (class 2) Abhydrolase_1 PF00561.20 KXH63836.1 - 0.059 13.0 0.0 0.073 12.7 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF900 PF05990.12 KXH63836.1 - 0.11 12.0 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Arrestin_N PF00339.29 KXH63837.1 - 2e-15 57.1 0.1 8.8e-11 42.1 0.0 3.0 4 0 0 4 4 4 2 Arrestin (or S-antigen), N-terminal domain zf-MIZ PF02891.20 KXH63838.1 - 2.1e-08 33.8 4.6 1.1e-06 28.2 0.5 2.6 2 0 0 2 2 2 2 MIZ/SP-RING zinc finger Hid1 PF12722.7 KXH63838.1 - 0.01 14.0 2.4 0.018 13.2 2.4 1.4 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Glycoprotein_G PF00802.19 KXH63838.1 - 0.02 14.3 5.6 0.043 13.2 5.6 1.5 1 0 0 1 1 1 0 Pneumovirus attachment glycoprotein G R3H PF01424.22 KXH63838.1 - 0.056 13.4 2.9 0.14 12.2 2.9 1.7 1 0 0 1 1 1 0 R3H domain SAM_2 PF07647.17 KXH63839.1 - 3.6e-14 52.6 0.0 7.6e-14 51.6 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_9 PF14604.6 KXH63839.1 - 5e-12 45.5 0.0 1.3e-11 44.1 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KXH63839.1 - 2.1e-10 40.0 0.0 4.1e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 SH3 domain PH PF00169.29 KXH63839.1 - 8e-10 39.2 0.0 2.7e-09 37.5 0.0 1.9 1 0 0 1 1 1 1 PH domain SH3_2 PF07653.17 KXH63839.1 - 0.00028 20.5 0.0 0.00063 19.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain PH_11 PF15413.6 KXH63839.1 - 0.0016 18.8 0.0 0.0042 17.5 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 KXH63839.1 - 0.03 14.6 0.0 0.19 12.0 0.0 2.2 2 0 0 2 2 2 0 Pleckstrin homology domain SAM_1 PF00536.30 KXH63839.1 - 0.078 13.4 0.0 0.15 12.5 0.0 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Coatomer_E PF04733.14 KXH63841.1 - 1.3e-61 208.6 7.6 1.5e-61 208.4 7.6 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit ANAPC3 PF12895.7 KXH63841.1 - 1.6e-06 28.2 0.7 1.8 8.8 0.0 3.5 3 0 0 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 KXH63841.1 - 1.9e-05 25.1 25.4 0.0057 17.1 5.5 4.1 3 1 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 KXH63841.1 - 0.00036 20.8 16.8 0.15 12.3 2.3 4.7 4 2 1 5 5 5 4 Tetratricopeptide repeat TPR_1 PF00515.28 KXH63841.1 - 0.013 15.3 5.9 2.4 8.1 0.1 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.14 KXH63841.1 - 0.021 15.4 2.9 0.1 13.3 1.3 5.4 8 0 0 8 8 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 KXH63841.1 - 0.29 11.3 9.1 28 5.0 0.0 5.1 5 1 1 6 6 6 0 Tetratricopeptide repeat Type_III_YscG PF09477.10 KXH63841.1 - 0.33 11.0 3.5 4 7.5 0.1 3.3 1 1 3 4 4 4 0 Bacterial type II secretion system chaperone protein (type_III_yscG) TPR_14 PF13428.6 KXH63841.1 - 0.49 11.3 18.5 0.16 12.9 3.1 5.3 3 3 1 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 KXH63841.1 - 1.1 9.6 16.9 0.18 12.0 0.8 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.6 KXH63841.1 - 1.3 9.4 3.9 5.5 7.5 0.0 3.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 KXH63841.1 - 9 7.2 8.1 9 7.2 0.2 4.2 5 0 0 5 5 4 0 Tetratricopeptide repeat HAD PF12710.7 KXH63843.1 - 1.9e-24 87.1 0.1 2.6e-24 86.7 0.1 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 KXH63843.1 - 0.0024 17.3 0.0 0.012 15.1 0.0 1.8 1 1 0 1 1 1 1 Putative Phosphatase Hydrolase PF00702.26 KXH63843.1 - 0.059 13.6 1.0 0.09 13.1 0.1 1.9 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.12 KXH63843.1 - 0.068 12.7 0.0 0.15 11.5 0.0 1.7 2 0 0 2 2 2 0 Pyrimidine 5'-nucleotidase (UMPH-1) ETF_QO PF05187.13 KXH63863.1 - 7.5e-49 164.2 0.6 1.3e-48 163.4 0.6 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S DAO PF01266.24 KXH63863.1 - 3.2e-10 40.1 0.2 0.00014 21.6 0.4 2.4 1 1 1 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXH63863.1 - 1.6e-07 31.5 0.0 7.7e-07 29.2 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KXH63863.1 - 4e-06 26.2 0.4 0.00035 19.8 0.9 2.2 1 1 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 KXH63863.1 - 6.5e-06 25.6 0.1 5e-05 22.7 0.1 2.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXH63863.1 - 9.5e-05 21.3 0.5 0.00014 20.8 0.5 1.2 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.17 KXH63863.1 - 0.0001 21.6 0.0 0.00037 19.8 0.1 1.7 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.27 KXH63863.1 - 0.00019 21.9 0.1 0.88 10.2 0.2 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KXH63863.1 - 0.00097 18.1 0.1 0.063 12.1 0.2 2.2 2 0 0 2 2 2 1 Tryptophan halogenase FAD_oxidored PF12831.7 KXH63863.1 - 0.0011 18.4 0.1 0.0018 17.7 0.0 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KXH63863.1 - 0.0011 18.3 0.2 0.002 17.4 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 KXH63863.1 - 0.0019 18.2 0.2 0.0049 16.9 0.2 1.6 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 KXH63863.1 - 0.0048 16.2 0.2 0.0075 15.6 0.2 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KXH63863.1 - 0.0097 15.2 0.1 0.017 14.4 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 KXH63863.1 - 0.01 14.9 0.2 0.016 14.3 0.2 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Fer4_7 PF12838.7 KXH63863.1 - 0.036 14.7 0.9 0.097 13.3 0.9 1.7 1 0 0 1 1 1 0 4Fe-4S dicluster domain GIDA PF01134.22 KXH63863.1 - 0.059 12.4 0.1 0.09 11.8 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Fer4_2 PF12797.7 KXH63863.1 - 0.18 12.0 0.7 0.46 10.7 0.7 1.6 1 0 0 1 1 1 0 4Fe-4S binding domain Glyco_hydro_92 PF07971.12 KXH63864.1 - 1.1e-145 486.2 0.1 1.3e-145 485.9 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 KXH63864.1 - 1.4e-67 228.1 0.3 2.1e-67 227.5 0.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain Glyco_hydro_125 PF06824.11 KXH63865.1 - 6.9e-176 585.2 0.0 7.9e-176 585.0 0.0 1.0 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) HECT PF00632.25 KXH63866.1 - 8.8e-83 278.3 0.0 1.4e-82 277.6 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) RRM_1 PF00076.22 KXH63867.1 - 1.5e-83 274.6 7.2 1.5e-21 76.0 0.2 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 KXH63867.1 - 3.4e-26 91.2 0.8 1.6e-25 89.1 0.8 2.1 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.6 KXH63867.1 - 3.3e-09 36.4 0.0 0.019 14.6 0.0 5.0 2 1 2 5 5 5 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KXH63867.1 - 1.9e-05 24.5 0.1 0.0082 16.0 0.0 3.5 4 0 0 4 4 4 1 Occluded RNA-recognition motif RRM_7 PF16367.5 KXH63867.1 - 6e-05 23.1 0.3 0.84 9.8 0.0 5.1 5 0 0 5 5 5 1 RNA recognition motif Nup35_RRM_2 PF14605.6 KXH63867.1 - 0.0004 20.3 1.4 14 5.7 0.1 4.9 4 1 0 4 4 4 0 Nup53/35/40-type RNA recognition motif CbiG_mid PF11761.8 KXH63867.1 - 0.0011 19.1 0.0 14 5.8 0.0 3.7 3 0 0 3 3 3 0 Cobalamin biosynthesis central region YflT PF11181.8 KXH63867.1 - 0.031 14.8 6.2 0.27 11.8 0.5 3.4 3 0 0 3 3 3 0 Heat induced stress protein YflT OB_RNB PF08206.11 KXH63867.1 - 0.045 13.5 1.8 9 6.1 0.0 3.6 3 0 0 3 3 3 0 Ribonuclease B OB domain YqfQ PF14181.6 KXH63867.1 - 0.32 11.2 9.6 1.5 8.9 9.6 2.2 1 0 0 1 1 1 0 YqfQ-like protein NPR3 PF03666.13 KXH63867.1 - 0.44 9.3 7.2 0.73 8.6 7.2 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 PhetRS_B1 PF18262.1 KXH63867.1 - 0.54 10.5 3.7 30 4.9 0.0 3.4 3 1 0 3 3 3 0 Phe-tRNA synthetase beta subunit B1 domain CDC45 PF02724.14 KXH63867.1 - 1.6 7.0 13.6 2.3 6.4 13.6 1.2 1 0 0 1 1 1 0 CDC45-like protein Zip PF02535.22 KXH63867.1 - 2.6 7.2 4.0 4.4 6.4 4.0 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter DUF913 PF06025.12 KXH63867.1 - 3.3 6.6 5.3 5.6 5.8 5.3 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DHHA1 PF02272.19 KXH63867.1 - 3.7 8.0 10.7 5.6 7.4 0.2 3.1 3 0 0 3 3 2 0 DHHA1 domain Presenilin PF01080.17 KXH63867.1 - 6.6 5.4 8.2 9.5 4.9 8.2 1.2 1 0 0 1 1 1 0 Presenilin zf-C2H2 PF00096.26 KXH63918.1 - 0.0012 19.2 13.7 0.0077 16.6 0.5 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXH63918.1 - 0.0024 18.6 12.4 0.025 15.4 0.3 3.6 2 1 1 3 3 3 2 C2H2-type zinc finger Zap1_zf2 PF18217.1 KXH63918.1 - 0.008 16.1 0.7 0.017 15.1 0.7 1.5 1 0 0 1 1 1 1 Zap1 zinc finger 2 OTT_1508_deam PF14441.6 KXH63920.1 - 6.5e-17 61.3 0.1 1.3e-16 60.4 0.1 1.5 1 0 0 1 1 1 1 OTT_1508-like deaminase Rad52_Rad22 PF04098.15 KXH63923.1 - 8.3e-29 100.5 0.1 1.2e-28 100.0 0.1 1.1 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein Glyco_hydro_53 PF07745.13 KXH63925.1 - 4.6e-102 341.5 0.3 5.2e-102 341.3 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 Zn_clus PF00172.18 KXH63926.1 - 1.1e-08 35.1 9.3 1.7e-08 34.4 9.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KXH63926.1 - 0.03 13.1 0.2 0.044 12.6 0.2 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain Cys_Met_Meta_PP PF01053.20 KXH63927.1 - 3.8e-140 466.8 0.1 4.4e-140 466.6 0.1 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 KXH63927.1 - 7.4e-08 31.7 0.5 1.5e-07 30.7 0.5 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 KXH63927.1 - 1.8e-07 30.6 0.2 2.9e-07 30.0 0.2 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 KXH63927.1 - 5.2e-06 26.0 1.0 8.9e-06 25.2 1.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family GDC-P PF02347.16 KXH63927.1 - 0.013 14.4 0.5 0.021 13.7 0.5 1.2 1 0 0 1 1 1 0 Glycine cleavage system P-protein 2-Hacid_dh PF00389.30 KXH63927.1 - 0.056 13.1 0.1 0.11 12.1 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain F-box-like PF12937.7 KXH63928.1 - 0.011 15.6 1.1 0.025 14.5 0.5 2.0 2 0 0 2 2 2 0 F-box-like SBF PF01758.16 KXH63929.1 - 9.6e-47 159.2 16.1 9.6e-47 159.2 16.1 1.9 3 0 0 3 3 3 1 Sodium Bile acid symporter family Kinocilin PF15033.6 KXH63929.1 - 1.2 8.8 5.3 4.8 6.8 1.2 2.8 2 0 0 2 2 2 0 Kinocilin protein DUF1765 PF08578.10 KXH63930.1 - 4.8e-44 149.8 3.5 1.1e-43 148.7 3.5 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) Dicty_REP PF05086.12 KXH63930.1 - 2.6 5.9 9.5 4.9 5.0 9.5 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DDE_Tnp_1_assoc PF13808.6 KXH63931.1 - 0.18 11.8 0.0 0.36 10.9 0.0 1.4 1 0 0 1 1 1 0 DDE_Tnp_1-associated Ribosomal_S8e PF01201.22 KXH63932.1 - 2.8e-43 147.4 5.7 1.1e-42 145.5 5.7 1.9 1 1 0 1 1 1 1 Ribosomal protein S8e Red1 PF07964.11 KXH63932.1 - 3.4 5.8 11.3 4 5.5 11.3 1.0 1 0 0 1 1 1 0 Rec10 / Red1 Bud13 PF09736.9 KXH63932.1 - 5.4 7.4 17.6 12 6.2 17.6 1.6 1 1 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex Ribosomal_L21p PF00829.21 KXH63933.1 - 3.1e-11 43.4 0.0 4.1e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein Pkinase PF00069.25 KXH63934.1 - 3.7e-46 157.6 0.0 5.6e-46 157.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXH63934.1 - 2.9e-19 69.4 0.0 4.3e-19 68.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXH63934.1 - 0.0038 17.2 0.0 0.71 9.7 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 KXH63934.1 - 0.033 13.5 0.0 0.098 12.0 0.0 1.7 2 0 0 2 2 2 0 Kinase-like RIO1 PF01163.22 KXH63934.1 - 0.12 12.0 0.0 0.25 10.9 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Ribosomal_60s PF00428.19 KXH63935.1 - 1e-26 93.3 11.0 1.2e-26 93.1 11.0 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein EF-hand_14 PF17959.1 KXH63935.1 - 0.01 16.2 0.0 0.015 15.7 0.0 1.3 1 0 0 1 1 1 0 EF-hand domain UBA_6 PF18039.1 KXH63935.1 - 0.11 12.4 0.7 0.2 11.6 0.1 1.6 2 0 0 2 2 2 0 UBA-like domain EPL1 PF10513.9 KXH63936.1 - 6.3 7.2 9.8 10 6.5 9.6 1.7 1 1 0 1 1 1 0 Enhancer of polycomb-like eIF3_subunit PF08597.10 KXH63968.1 - 1.2e-71 241.5 23.9 1.3e-71 241.4 23.9 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit Anillin_N PF16018.5 KXH63968.1 - 0.011 16.4 0.2 0.011 16.4 0.2 3.2 3 1 1 4 4 4 0 Anillin N-terminus DUF572 PF04502.13 KXH63968.1 - 0.07 12.7 16.8 0.11 12.1 16.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) PRP4 PF08799.11 KXH63968.1 - 0.81 9.3 5.3 1.7 8.3 5.3 1.5 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like Nop53 PF07767.11 KXH63968.1 - 2.2 7.6 26.3 0.24 10.8 18.0 2.1 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) CDC45 PF02724.14 KXH63968.1 - 4.6 5.4 13.9 7 4.8 13.9 1.3 1 0 0 1 1 1 0 CDC45-like protein AOX PF01786.17 KXH63970.1 - 1.6e-90 302.4 0.0 2.1e-90 302.0 0.0 1.2 1 0 0 1 1 1 1 Alternative oxidase Rad4 PF03835.15 KXH63972.1 - 1.7e-14 53.7 0.9 3e-14 52.9 0.9 1.4 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Transglut_core PF01841.19 KXH63972.1 - 1.2e-11 45.1 1.5 2.7e-11 43.9 1.5 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily Fungal_trans PF04082.18 KXH64005.1 - 9.6e-10 37.9 0.0 2.1e-09 36.8 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH64005.1 - 3.2e-07 30.4 15.1 5.3e-07 29.7 15.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NAD_binding_10 PF13460.6 KXH64006.1 - 4.2e-10 39.8 0.0 4.5e-10 39.7 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding TTc_toxin_rep PF18807.1 KXH64006.1 - 0.15 11.9 0.1 0.25 11.2 0.1 1.3 1 0 0 1 1 1 0 Tripartite Tc toxins repeat Ras PF00071.22 KXH64027.1 - 3.6e-54 182.7 0.0 4.1e-54 182.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXH64027.1 - 1.9e-21 76.5 0.0 2.7e-21 76.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXH64027.1 - 8.5e-07 28.6 0.0 1.1e-06 28.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Epimerase PF01370.21 KXH64028.1 - 3.7e-12 46.2 0.0 6.4e-12 45.5 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXH64028.1 - 6.9e-07 28.6 0.0 2e-06 27.1 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KXH64028.1 - 0.00028 20.8 0.3 0.0028 17.6 0.3 2.4 1 1 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KXH64028.1 - 0.0015 17.8 0.7 0.021 14.0 0.7 2.1 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 KXH64028.1 - 0.011 15.1 0.0 0.021 14.2 0.0 1.5 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase adh_short PF00106.25 KXH64028.1 - 0.081 12.4 1.0 4.9 6.6 0.4 2.8 2 1 0 2 2 2 0 short chain dehydrogenase CENP-T_C PF15511.6 KXH64029.1 - 5.4e-45 151.9 0.1 9.1e-45 151.2 0.1 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KXH64029.1 - 1.9e-08 34.6 0.0 3.1e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein Histone PF00125.24 KXH64029.1 - 0.00012 22.4 0.0 0.00032 21.1 0.0 1.8 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KXH64029.1 - 0.0013 19.0 0.0 0.0029 17.9 0.0 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone SURF1 PF02104.15 KXH64030.1 - 4e-49 167.2 0.1 5.7e-49 166.7 0.1 1.1 1 0 0 1 1 1 1 SURF1 family UBX PF00789.20 KXH64031.1 - 3.3e-10 40.0 0.0 5.9e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 UBX domain TFIIA PF03153.13 KXH64031.1 - 0.099 12.6 8.5 0.13 12.2 8.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Thioredoxin_7 PF13899.6 KXH64031.1 - 0.12 12.6 0.5 0.48 10.6 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin-like TMPIT PF07851.13 KXH64031.1 - 7.7 5.7 5.1 11 5.1 5.1 1.1 1 0 0 1 1 1 0 TMPIT-like protein Borrelia_P83 PF05262.11 KXH64031.1 - 8.4 4.8 17.0 12 4.3 17.0 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF2076 PF09849.9 KXH64032.1 - 3.2e-07 30.7 13.8 4.1e-07 30.3 13.8 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.13 KXH64032.1 - 0.00015 21.8 4.0 0.0002 21.4 4.0 1.2 1 0 0 1 1 1 1 CHCH domain GCK PF07802.11 KXH64032.1 - 0.017 15.5 0.4 0.034 14.5 0.4 1.5 1 1 0 1 1 1 0 GCK domain Trypan_glycop_C PF10659.9 KXH64032.1 - 0.039 14.3 2.0 0.06 13.7 2.0 1.3 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein C-terminal domain Kisspeptin PF15152.6 KXH64032.1 - 0.28 12.0 3.7 5 8.0 0.2 2.3 2 0 0 2 2 2 0 Kisspeptin CX9C PF16860.5 KXH64032.1 - 2.1 8.5 5.1 0.7 10.0 0.7 1.6 1 1 1 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Sas10_Utp3 PF04000.15 KXH64033.1 - 2.4e-15 56.9 0.9 2.4e-15 56.9 0.9 1.9 2 0 0 2 2 2 1 Sas10/Utp3/C1D family DUF3619 PF12279.8 KXH64033.1 - 0.2 12.0 1.8 0.43 10.9 1.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3619) COG2 PF06148.11 KXH64033.1 - 0.3 11.2 3.4 6.4 6.9 0.0 2.8 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF5302 PF17227.2 KXH64033.1 - 0.91 10.6 6.9 0.57 11.2 4.7 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5302) ApbA_C PF08546.11 KXH64034.1 - 3.7e-18 65.9 0.0 8.8e-18 64.7 0.0 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 KXH64034.1 - 1.2e-06 28.3 0.0 2.4e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA dsDNA_bind PF01984.20 KXH64035.1 - 2.1e-42 143.9 14.0 2.5e-42 143.7 14.0 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain K_channel_TID PF07941.11 KXH64035.1 - 0.011 16.1 7.7 0.022 15.2 7.7 1.5 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain Fes1 PF08609.10 KXH64035.1 - 0.044 14.7 2.5 0.062 14.2 1.4 1.7 1 1 0 1 1 1 0 Nucleotide exchange factor Fes1 DUF2973 PF11189.8 KXH64035.1 - 0.21 11.7 0.4 0.43 10.7 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2973) Tom5 PF10642.9 KXH64035.1 - 0.43 10.7 2.6 1.3 9.1 2.6 1.8 1 0 0 1 1 1 0 Mitochondrial import receptor subunit or translocase CDT1_C PF16679.5 KXH64035.1 - 0.87 10.1 6.6 1.4 9.4 6.6 1.4 1 1 0 1 1 1 0 DNA replication factor Cdt1 C-terminal domain DUF4670 PF15709.5 KXH64035.1 - 4.6 6.4 17.1 6.3 6.0 17.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4670) Coq4 PF05019.13 KXH64036.1 - 1.3e-92 309.1 0.0 1.6e-92 308.8 0.0 1.1 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 SET PF00856.28 KXH64037.1 - 4e-10 40.3 0.0 5.6e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 SET domain RRM_1 PF00076.22 KXH64038.1 - 0.00065 19.5 0.0 0.0011 18.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Prothymosin PF03247.14 KXH64038.1 - 1.7 9.2 14.6 5.1 7.6 14.6 1.8 1 0 0 1 1 1 0 Prothymosin/parathymosin family SecE PF00584.20 KXH64039.1 - 1e-14 54.2 0.0 1.1e-14 54.0 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex WD40 PF00400.32 KXH64040.1 - 1.3e-21 76.5 17.8 0.00017 22.3 0.6 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXH64040.1 - 0.00031 21.0 0.0 0.15 12.4 0.0 3.4 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 KXH64040.1 - 0.0021 16.6 4.5 0.26 9.8 0.0 3.9 3 1 1 4 4 4 2 Cytochrome D1 heme domain PD40 PF07676.12 KXH64040.1 - 0.021 14.7 0.3 0.15 12.0 0.0 2.6 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat BUD22 PF09073.10 KXH64040.1 - 0.66 9.2 8.2 1 8.6 8.2 1.3 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 KXH64040.1 - 1.7 8.0 6.8 2.5 7.4 6.8 1.3 1 0 0 1 1 1 0 SDA1 UPF0016 PF01169.19 KXH64041.1 - 8.3e-41 138.2 25.0 2.1e-20 72.8 7.2 2.2 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 UPF0370 PF13980.6 KXH64041.1 - 0.092 12.8 0.1 0.27 11.3 0.1 1.8 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0370) HET PF06985.11 KXH64042.1 - 5.2e-23 82.0 0.0 1.9e-22 80.2 0.0 2.0 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Pkinase PF00069.25 KXH64043.1 - 3.8e-10 39.6 0.0 6.6e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain AA_permease_2 PF13520.6 KXH64044.1 - 1.3e-31 109.9 14.5 1.3e-31 109.9 14.5 2.1 1 1 0 2 2 2 1 Amino acid permease MerT PF02411.15 KXH64044.1 - 0.12 12.4 2.1 0.46 10.5 0.4 2.7 2 0 0 2 2 2 0 MerT mercuric transport protein Frag1 PF10277.9 KXH64044.1 - 9.1 5.7 18.1 0.47 10.0 1.9 3.4 2 2 0 2 2 2 0 Frag1/DRAM/Sfk1 family AhpC-TSA PF00578.21 KXH64045.1 - 1.3e-29 102.7 0.0 1.7e-29 102.3 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KXH64045.1 - 6.2e-12 45.5 0.0 8.3e-12 45.1 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 KXH64045.1 - 2.7e-11 43.1 0.1 5.9e-11 42.0 0.1 1.6 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Abhydrolase_6 PF12697.7 KXH64046.1 - 3.8e-07 31.0 11.0 5.2e-07 30.5 11.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXH64046.1 - 2.1e-05 24.3 0.1 6.7e-05 22.7 0.2 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold AMP-binding PF00501.28 KXH64048.1 - 5.6e-74 249.2 0.0 8.5e-74 248.6 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXH64048.1 - 2.3e-10 41.3 0.1 5.4e-10 40.1 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Coronavirus_5 PF05528.11 KXH64048.1 - 0.12 12.4 0.0 20 5.3 0.0 3.5 4 0 0 4 4 4 0 Coronavirus gene 5 protein Yip1 PF04893.17 KXH64050.1 - 0.046 13.4 0.6 0.088 12.5 0.6 1.6 1 0 0 1 1 1 0 Yip1 domain Syndecan PF01034.20 KXH64050.1 - 0.13 12.2 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 Syndecan domain Rick_17kDa_Anti PF05433.15 KXH64050.1 - 1.4 8.8 22.7 0.82 9.6 0.4 3.5 3 0 0 3 3 3 0 Glycine zipper 2TM domain ABC_tran PF00005.27 KXH64062.1 - 1.8e-49 167.7 0.0 5.4e-29 101.5 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KXH64062.1 - 4.4e-38 131.5 19.9 3.9e-19 69.4 6.0 3.3 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 KXH64062.1 - 8.7e-09 35.1 2.1 0.0081 15.6 0.0 4.2 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KXH64062.1 - 2.2e-07 31.6 2.9 0.00023 21.7 0.1 2.7 3 0 0 3 3 2 2 AAA domain AAA_29 PF13555.6 KXH64062.1 - 9e-07 28.5 1.8 0.021 14.5 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KXH64062.1 - 5.8e-06 26.8 0.1 0.052 13.9 0.0 2.9 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.6 KXH64062.1 - 7.2e-06 25.7 0.0 0.15 11.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.6 KXH64062.1 - 8.8e-05 22.4 2.3 2.3 8.0 0.5 3.6 3 1 0 4 4 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KXH64062.1 - 0.0001 22.6 0.2 0.57 10.5 0.1 3.2 2 1 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KXH64062.1 - 0.00011 22.1 0.0 0.36 10.7 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase NB-ARC PF00931.22 KXH64062.1 - 0.00024 20.4 0.0 0.46 9.6 0.0 3.5 3 1 0 3 3 3 1 NB-ARC domain T2SSE PF00437.20 KXH64062.1 - 0.00026 20.1 0.4 0.064 12.3 0.1 2.6 2 0 0 2 2 2 1 Type II/IV secretion system protein Viral_helicase1 PF01443.18 KXH64062.1 - 0.00034 20.4 0.1 0.14 11.9 0.0 2.6 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase MMR_HSR1 PF01926.23 KXH64062.1 - 0.00041 20.4 0.7 0.04 14.0 0.1 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase SbcCD_C PF13558.6 KXH64062.1 - 0.0012 19.1 0.0 1 9.6 0.0 2.9 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit cobW PF02492.19 KXH64062.1 - 0.0021 17.7 2.3 0.61 9.7 1.2 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 KXH64062.1 - 0.0024 17.8 0.3 2.5 8.0 0.1 2.5 2 0 0 2 2 2 2 NACHT domain DUF87 PF01935.17 KXH64062.1 - 0.0034 17.5 4.8 0.0046 17.1 0.1 2.3 2 0 0 2 2 2 1 Helicase HerA, central domain Pox_A32 PF04665.12 KXH64062.1 - 0.01 15.3 2.4 0.4 10.1 0.1 2.3 2 0 0 2 2 2 1 Poxvirus A32 protein AAA_33 PF13671.6 KXH64062.1 - 0.013 15.7 0.2 8.4 6.5 0.1 2.7 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KXH64062.1 - 0.016 14.9 0.8 1.3 8.7 0.1 2.9 3 0 0 3 3 3 0 AAA domain MobB PF03205.14 KXH64062.1 - 0.018 14.9 0.7 1.2 9.0 0.1 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.18 KXH64062.1 - 0.023 14.0 0.1 0.45 9.8 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family DEAD PF00270.29 KXH64062.1 - 0.025 14.4 0.1 2.9 7.6 0.1 2.8 2 1 0 2 2 2 0 DEAD/DEAH box helicase Dynamin_N PF00350.23 KXH64062.1 - 0.025 14.6 0.8 4 7.5 0.1 2.4 2 0 0 2 2 2 0 Dynamin family AAA_18 PF13238.6 KXH64062.1 - 0.035 14.7 0.1 10 6.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 KXH64062.1 - 0.052 13.3 0.3 1.5 8.4 0.1 2.2 2 0 0 2 2 2 0 AAA ATPase domain NTPase_1 PF03266.15 KXH64062.1 - 0.058 13.3 2.1 6.3 6.7 0.0 2.5 2 0 0 2 2 2 0 NTPase CbiA PF01656.23 KXH64062.1 - 0.067 13.2 0.1 6 6.9 0.0 2.9 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_10 PF12846.7 KXH64062.1 - 0.069 12.1 0.0 0.13 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain DUF2075 PF09848.9 KXH64062.1 - 0.072 12.3 0.2 0.75 9.0 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_14 PF13173.6 KXH64062.1 - 0.13 12.3 0.1 14 5.7 0.0 2.7 3 0 0 3 3 2 0 AAA domain AAA_24 PF13479.6 KXH64062.1 - 0.17 11.6 0.3 9.5 5.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KXH64062.1 - 0.23 10.9 0.2 3 7.3 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region Septin PF00735.18 KXH64062.1 - 0.24 10.7 0.1 13 5.0 0.0 2.2 2 0 0 2 2 2 0 Septin ATPase PF06745.13 KXH64062.1 - 0.29 10.4 3.1 38 3.5 0.0 3.2 3 0 0 3 3 3 0 KaiC Aldolase_II PF00596.21 KXH64063.1 - 3e-44 151.2 0.0 5.4e-44 150.3 0.0 1.4 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain DUF3148 PF11347.8 KXH64063.1 - 0.19 11.5 0.0 0.45 10.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3148) NAD_binding_10 PF13460.6 KXH64114.1 - 3.1e-12 46.8 0.0 3.5e-12 46.6 0.0 1.0 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KXH64114.1 - 2.3e-06 27.3 0.0 2.6e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 KXH64114.1 - 0.0035 16.8 0.0 0.0039 16.7 0.0 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GARS_N PF02844.15 KXH64114.1 - 0.19 12.5 0.0 0.19 12.5 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, N domain AAR2 PF05282.11 KXH64124.1 - 2.3e-53 181.9 0.0 4.6e-53 180.9 0.0 1.4 1 1 0 1 1 1 1 AAR2 protein DEAD PF00270.29 KXH64125.1 - 6.4e-50 169.3 0.0 7.9e-49 165.8 0.0 2.1 1 1 2 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXH64125.1 - 1.4e-30 105.9 0.0 4.2e-30 104.4 0.1 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXH64125.1 - 4.5e-05 23.5 0.0 0.00031 20.8 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 KXH64125.1 - 0.0029 16.4 0.0 0.39 9.4 0.0 2.3 2 0 0 2 2 2 2 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 AAA_19 PF13245.6 KXH64125.1 - 0.018 15.4 0.0 9 6.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain Helicase_C_2 PF13307.6 KXH64125.1 - 0.019 15.2 0.0 0.032 14.4 0.0 1.3 1 0 0 1 1 1 0 Helicase C-terminal domain DUF2443 PF10398.9 KXH64125.1 - 0.12 12.5 0.3 0.26 11.3 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2443) RICTOR_N PF14664.6 KXH64126.1 - 2.8e-130 434.6 3.2 1.1e-129 432.6 3.4 1.9 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, N-term RasGEF_N_2 PF14663.6 KXH64126.1 - 5e-38 129.8 0.6 2.5e-33 114.7 0.0 3.9 3 0 0 3 3 3 2 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_M PF14666.6 KXH64126.1 - 2.9e-37 126.6 0.0 6.9e-34 115.7 0.0 4.2 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, middle domain RICTOR_V PF14668.6 KXH64126.1 - 8.4e-31 106.0 0.2 1.9e-28 98.5 0.1 4.1 5 0 0 5 5 5 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.16 KXH64126.1 - 2.7e-14 53.0 9.6 8.9e-14 51.4 9.6 2.0 1 0 0 1 1 1 1 Hr1 repeat Uds1 PF15456.6 KXH64126.1 - 0.023 14.9 5.0 0.07 13.3 5.0 1.9 1 0 0 1 1 1 0 Up-regulated During Septation V_ATPase_I PF01496.19 KXH64126.1 - 0.28 9.1 0.7 0.46 8.4 0.7 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF883 PF05957.13 KXH64126.1 - 6 7.5 6.3 18 6.0 2.1 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) CENP-K PF11802.8 KXH64126.1 - 8.7 5.8 8.7 3.5 7.1 5.8 1.7 2 0 0 2 2 2 0 Centromere-associated protein K Uricase PF01014.18 KXH64128.1 - 9.1e-78 258.9 0.7 1.6e-40 138.4 0.4 2.0 2 0 0 2 2 2 2 Uricase Ribosomal_L13 PF00572.18 KXH64129.1 - 5.2e-41 139.8 0.0 7.5e-41 139.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L13 HMA PF00403.26 KXH64130.1 - 7.6e-10 39.1 0.1 1.3e-09 38.4 0.1 1.3 1 0 0 1 1 1 1 Heavy-metal-associated domain Sod_Cu PF00080.20 KXH64130.1 - 1.8e-09 37.9 0.0 2.8e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Chordopox_RPO7 PF05864.12 KXH64130.1 - 0.037 14.3 0.3 0.8 10.0 0.0 2.2 2 0 0 2 2 2 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) TPR_1 PF00515.28 KXH64131.1 - 4.1e-18 64.4 6.8 7.4e-09 35.1 0.0 4.6 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.17 KXH64131.1 - 7.4e-16 56.9 6.9 1.2e-06 28.2 0.0 4.6 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_12 PF13424.6 KXH64131.1 - 1.7e-11 44.2 0.6 2.9e-07 30.7 0.1 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KXH64131.1 - 5.6e-11 41.7 3.8 3e-06 27.0 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 KXH64131.1 - 6.7e-09 35.8 0.4 0.061 14.0 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 KXH64131.1 - 3.5e-08 32.9 0.2 9.9e-06 25.2 0.0 3.6 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 KXH64131.1 - 6.9e-08 32.0 1.7 6.4e-06 25.8 0.2 3.7 2 1 1 3 3 3 1 TPR repeat PB1 PF00564.24 KXH64131.1 - 1.6e-06 28.0 0.1 3e-06 27.1 0.1 1.4 1 0 0 1 1 1 1 PB1 domain TPR_16 PF13432.6 KXH64131.1 - 5.6e-05 23.7 0.1 0.0061 17.2 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 KXH64131.1 - 8.2e-05 22.7 0.1 0.15 12.5 0.1 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 KXH64131.1 - 0.00013 22.0 0.2 0.19 11.9 0.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 KXH64131.1 - 0.00086 19.1 1.1 0.23 11.4 0.0 3.7 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 KXH64131.1 - 0.0036 18.0 0.2 0.18 12.7 0.0 3.3 1 1 2 3 3 3 1 Tetratricopeptide repeat DUF3808 PF10300.9 KXH64131.1 - 0.078 11.7 0.0 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3808) TPR_4 PF07721.14 KXH64131.1 - 0.095 13.4 0.4 46 5.0 0.0 3.8 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 KXH64131.1 - 0.1 13.1 0.0 1.3 9.6 0.0 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat tRNA-synt_1c PF00749.21 KXH64132.1 - 1.2e-92 310.1 0.0 1.7e-92 309.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain DnaJ_C PF01556.18 KXH64133.1 - 3.5e-37 127.8 0.1 4.7e-37 127.3 0.1 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KXH64133.1 - 3e-23 81.7 4.6 5.2e-23 80.9 4.6 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KXH64133.1 - 1.1e-12 48.1 21.2 1.9e-12 47.4 21.2 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 KXH64133.1 - 0.069 13.1 14.3 0.96 9.5 3.7 2.5 2 0 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 KXH64133.1 - 2.3 8.3 11.2 5.5 7.0 1.0 2.3 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF1356 PF07092.12 KXH64133.1 - 4.1 6.6 4.8 7.2 5.8 0.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1356) Ribosomal_L32e PF01655.18 KXH64134.1 - 4e-49 165.5 0.8 4e-49 165.5 0.8 1.4 1 1 1 2 2 2 1 Ribosomal protein L32 SH3_1 PF00018.28 KXH64136.1 - 3.6e-05 23.3 0.0 7.4e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KXH64136.1 - 0.052 13.4 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Variant SH3 domain Crystall_4 PF17945.1 KXH64136.1 - 0.11 12.9 0.1 0.45 11.0 0.0 2.0 2 0 0 2 2 2 0 Beta/Gamma crystallin Bac_rhamnosid_C PF17390.2 KXH64137.1 - 5.6e-07 29.3 0.9 1.1e-06 28.3 0.9 1.5 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain GDE_C PF06202.14 KXH64137.1 - 8.6e-07 28.2 0.0 1.2e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase Bac_rhamnosid6H PF17389.2 KXH64137.1 - 1.6e-06 27.6 0.3 3.3e-06 26.6 0.1 1.5 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Glyco_hydro_36 PF17167.4 KXH64137.1 - 0.014 14.1 0.4 0.03 13.0 0.4 1.4 1 1 0 1 1 1 0 Glycosyl hydrolase 36 superfamily, catalytic domain DUF608 PF04685.13 KXH64137.1 - 0.025 13.8 0.1 0.039 13.1 0.1 1.2 1 0 0 1 1 1 0 Glycosyl-hydrolase family 116, catalytic region Glyco_hydro_76 PF03663.14 KXH64137.1 - 0.058 12.9 0.5 0.12 11.9 0.5 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 76 Ig_6 PF18452.1 KXH64138.1 - 0.067 12.8 0.6 0.099 12.2 0.6 1.2 1 0 0 1 1 1 0 Immunoglobulin domain Aminotran_1_2 PF00155.21 KXH64139.1 - 3.6e-60 204.0 0.0 4.8e-60 203.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Cobl PF09469.10 KXH64142.1 - 0.15 12.3 0.0 0.29 11.4 0.0 1.4 1 0 0 1 1 1 0 Cordon-bleu ubiquitin-like domain Aldo_ket_red PF00248.21 KXH64151.1 - 4.4e-67 226.4 0.0 5.4e-67 226.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family COesterase PF00135.28 KXH64152.1 - 3e-82 277.1 0.0 3.9e-82 276.7 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXH64152.1 - 0.00031 20.7 0.1 0.0017 18.2 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Pec_lyase_C PF00544.19 KXH64153.1 - 2.4e-33 115.5 7.5 3.3e-33 115.0 7.5 1.1 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 KXH64153.1 - 2.7e-05 24.0 7.5 0.0006 19.7 7.3 2.2 1 1 0 1 1 1 1 Right handed beta helix region DAGK_cat PF00781.24 KXH64187.1 - 6.3e-08 32.3 0.0 2.4e-07 30.4 0.0 1.9 1 1 0 1 1 1 1 Diacylglycerol kinase catalytic domain TRM PF02005.16 KXH64188.1 - 2e-106 356.4 0.0 3.4e-93 312.8 0.0 2.1 2 0 0 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase FixO PF02433.15 KXH64188.1 - 0.04 13.4 1.2 0.097 12.1 1.2 1.6 1 0 0 1 1 1 0 Cytochrome C oxidase, mono-heme subunit/FixO TFB6 PF17110.5 KXH64188.1 - 3.2 7.5 6.6 7 6.4 6.6 1.5 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH DSBA PF01323.20 KXH64220.1 - 2.1e-20 73.3 0.0 2.3e-20 73.2 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain zf-RING_2 PF13639.6 KXH64221.1 - 1.3e-07 31.8 13.8 2.2e-07 31.1 13.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KXH64221.1 - 2.4e-05 24.5 11.0 5.5e-05 23.4 11.0 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 KXH64221.1 - 4.9e-05 23.1 10.0 7.2e-05 22.6 10.0 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXH64221.1 - 0.00012 21.8 10.2 0.0002 21.1 10.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXH64221.1 - 0.00026 20.7 13.9 0.00043 20.1 13.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KXH64221.1 - 0.095 12.6 7.5 0.17 11.8 7.5 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KXH64221.1 - 1.7 8.8 6.4 4.3 7.5 6.5 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 KXH64221.1 - 1.7 8.4 9.6 4.2 7.2 9.6 1.6 1 0 0 1 1 1 0 RING-like zinc finger Drc1-Sld2 PF11719.8 KXH64222.1 - 2.5e-92 310.8 29.3 2.8e-92 310.6 29.3 1.0 1 0 0 1 1 1 1 DNA replication and checkpoint protein RRN3 PF05327.11 KXH64222.1 - 0.18 10.3 2.8 0.28 9.7 2.8 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Inhibitor_I53 PF11714.8 KXH64222.1 - 0.58 10.4 3.9 2.1 8.6 3.9 2.0 1 0 0 1 1 1 0 Thrombin inhibitor Madanin NUDIX_5 PF16705.5 KXH64223.1 - 0.17 11.6 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 NUDIX, or N-terminal NPxY motif-rich, region of KRIT FMO-like PF00743.19 KXH64224.1 - 2.8e-30 105.2 0.0 6.6e-15 54.5 0.0 3.0 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KXH64224.1 - 2.2e-14 53.4 0.0 2e-09 37.1 0.0 2.5 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXH64224.1 - 8e-13 48.3 0.3 1.2e-07 31.4 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXH64224.1 - 1.1e-11 45.0 0.1 1.5e-05 25.0 0.0 3.5 3 0 0 3 3 3 3 FAD-NAD(P)-binding K_oxygenase PF13434.6 KXH64224.1 - 1.8e-09 37.2 0.5 1.6e-06 27.5 0.0 3.3 3 1 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KXH64224.1 - 0.00061 20.0 0.4 0.0018 18.5 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXH64224.1 - 0.00065 19.4 2.4 0.2 11.2 0.5 3.4 3 0 0 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.17 KXH64224.1 - 0.0021 17.3 0.3 0.031 13.5 0.1 2.2 2 0 0 2 2 2 1 Thi4 family UPF0149 PF03695.13 KXH64224.1 - 0.012 16.0 0.3 0.019 15.3 0.3 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0149) Semialdhyde_dh PF01118.24 KXH64224.1 - 0.15 12.5 0.0 0.47 10.9 0.0 1.9 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain MFS_1 PF07690.16 KXH64225.1 - 2.6e-35 122.0 18.6 2.6e-35 122.0 18.6 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily CbtA PF09490.10 KXH64225.1 - 0.0045 16.8 5.2 0.61 9.8 1.4 3.2 3 0 0 3 3 3 2 Probable cobalt transporter subunit (CbtA) Cation_ATPase_C PF00689.21 KXH64225.1 - 0.45 10.2 0.0 0.45 10.2 0.0 3.3 2 2 1 3 3 3 0 Cation transporting ATPase, C-terminus Alk_phosphatase PF00245.20 KXH64226.1 - 9.9e-84 281.7 0.0 1.2e-83 281.5 0.0 1.0 1 0 0 1 1 1 1 Alkaline phosphatase DNA_methylase PF00145.17 KXH64228.1 - 2.6e-32 112.5 0.0 5.1e-32 111.5 0.0 1.4 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase BAH PF01426.18 KXH64228.1 - 4.2e-06 26.6 0.0 0.0061 16.4 0.0 2.5 2 0 0 2 2 2 2 BAH domain DUF155 PF02582.14 KXH64229.1 - 9.2e-48 162.6 0.0 1.3e-47 162.1 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Cupin_1 PF00190.22 KXH64229.1 - 0.18 11.4 0.0 0.34 10.5 0.0 1.5 1 0 0 1 1 1 0 Cupin BTB PF00651.31 KXH64231.1 - 0.00067 19.9 0.2 0.0031 17.7 0.2 2.3 1 1 0 1 1 1 1 BTB/POZ domain FAM27 PF15832.5 KXH64232.1 - 0.036 14.6 5.0 0.072 13.6 5.0 1.5 1 0 0 1 1 1 0 FAM27 D and E protein family TPP_enzyme_N PF02776.18 KXH64232.1 - 0.16 11.6 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain DUF3915 PF13054.6 KXH64232.1 - 2.6 8.0 8.8 2.2 8.3 7.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3915) Atrophin-1 PF03154.15 KXH64232.1 - 5.1 5.3 12.6 7.4 4.7 12.6 1.2 1 0 0 1 1 1 0 Atrophin-1 family DIE2_ALG10 PF04922.12 KXH64239.1 - 7.3e-120 400.9 4.1 9e-83 278.7 0.3 2.1 2 0 0 2 2 2 2 DIE2/ALG10 family GST_C_2 PF13410.6 KXH64239.1 - 0.32 11.0 1.6 10 6.2 0.2 2.7 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Spt20 PF12090.8 KXH64240.1 - 1.1 8.8 6.8 1.4 8.5 6.8 1.0 1 0 0 1 1 1 0 Spt20 family DUF1180 PF06679.12 KXH64240.1 - 1.3 9.5 5.4 1.5 9.2 5.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Miga PF10265.9 KXH64240.1 - 5.3 5.9 5.9 6.4 5.6 5.9 1.0 1 0 0 1 1 1 0 Mitoguardin ToxB_N PF18224.1 KXH64241.1 - 1e-24 86.2 0.3 1.2e-24 86.0 0.3 1.1 1 0 0 1 1 1 1 ToxB N-terminal domain U-box PF04564.15 KXH64243.1 - 1.3e-18 66.9 0.0 2.5e-18 66.0 0.0 1.5 1 0 0 1 1 1 1 U-box domain TPR_2 PF07719.17 KXH64243.1 - 5e-10 38.7 7.5 0.00014 21.7 0.2 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KXH64243.1 - 4.8e-07 29.3 6.3 0.0084 15.9 0.2 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 KXH64243.1 - 6.5e-07 28.9 0.5 6.5e-07 28.9 0.5 2.7 2 1 1 3 3 3 1 TPR repeat TPR_19 PF14559.6 KXH64243.1 - 8.3e-07 29.4 4.8 0.0008 19.9 0.1 2.6 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 KXH64243.1 - 5.4e-06 27.0 7.0 0.00024 21.7 0.2 3.0 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 KXH64243.1 - 6.4e-06 26.6 4.5 0.0049 17.6 0.1 3.1 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 KXH64243.1 - 9.3e-05 22.7 7.2 0.06 13.6 3.7 3.2 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 KXH64243.1 - 0.00011 22.3 2.4 0.038 14.4 0.1 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 KXH64243.1 - 0.0077 16.4 0.7 0.038 14.1 0.1 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KXH64243.1 - 0.0091 16.2 3.4 0.036 14.3 3.4 2.0 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 KXH64243.1 - 0.013 15.7 1.5 2.7 8.4 0.0 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 KXH64243.1 - 0.022 14.6 9.5 0.044 13.7 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat CHIP_TPR_N PF18391.1 KXH64243.1 - 0.063 14.1 13.2 0.16 12.7 13.2 1.7 1 0 0 1 1 1 0 CHIP N-terminal tetratricopeptide repeat domain TPR_4 PF07721.14 KXH64243.1 - 0.14 12.8 0.9 7.3 7.5 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KXH64243.1 - 0.2 11.7 3.1 0.37 10.9 0.5 2.8 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 KXH64243.1 - 0.33 11.4 2.7 1.1 9.7 0.1 2.3 1 1 0 2 2 2 0 Alkyl sulfatase dimerisation TPR_7 PF13176.6 KXH64243.1 - 0.51 10.5 3.7 2.6 8.3 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 KXH64243.1 - 1.1 10.1 6.4 5.4 7.9 1.0 3.5 4 0 0 4 4 2 0 Tetratricopeptide repeat SAE2 PF08573.10 KXH64243.1 - 1.1 10.4 4.4 1.9 9.6 4.4 1.4 1 0 0 1 1 1 0 DNA repair protein endonuclease SAE2/CtIP C-terminus GMC_oxred_N PF00732.19 KXH64245.1 - 7.7e-69 232.3 0.0 1e-68 231.9 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXH64245.1 - 3.3e-37 128.2 0.0 6.9e-37 127.2 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_3 PF13738.6 KXH64245.1 - 6.5e-06 25.6 0.4 0.12 11.6 0.0 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXH64245.1 - 1.5e-05 24.8 5.4 0.00012 21.8 5.4 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KXH64245.1 - 2.1e-05 23.8 1.7 0.029 13.5 0.6 2.5 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.17 KXH64245.1 - 6.1e-05 22.4 0.0 0.00012 21.4 0.0 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 KXH64245.1 - 0.00015 22.0 1.1 0.00028 21.1 0.3 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXH64245.1 - 0.00092 18.5 1.3 0.31 10.2 0.4 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KXH64245.1 - 0.0014 17.8 0.2 0.0023 17.0 0.2 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.14 KXH64245.1 - 0.0071 15.1 1.1 0.094 11.4 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein K_oxygenase PF13434.6 KXH64245.1 - 0.12 11.5 0.2 5.7 6.0 0.0 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 KXH64245.1 - 0.18 12.4 0.3 7 7.3 0.1 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXH64245.1 - 0.21 11.6 1.5 0.3 11.1 0.1 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding 2-Hacid_dh_C PF02826.19 KXH64246.1 - 9.9e-40 135.8 0.0 1.9e-39 134.9 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KXH64246.1 - 2.4e-10 40.2 0.0 3.5e-10 39.7 0.0 1.4 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KXH64246.1 - 0.0025 18.0 0.1 0.0053 16.9 0.1 1.5 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KXH64246.1 - 0.0065 17.0 0.1 0.013 16.1 0.1 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent UDPG_MGDP_dh_C PF03720.15 KXH64246.1 - 0.0092 16.4 0.2 1.1 9.7 0.1 2.5 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Sacchrp_dh_NADP PF03435.18 KXH64246.1 - 0.0096 16.2 0.2 0.098 12.9 0.1 2.2 1 1 1 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Gp_dh_N PF00044.24 KXH64246.1 - 0.02 15.3 0.0 0.063 13.6 0.0 1.8 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KXH64246.1 - 0.03 14.4 0.0 0.055 13.5 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DapB_N PF01113.20 KXH64246.1 - 0.053 13.6 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus GFO_IDH_MocA PF01408.22 KXH64246.1 - 0.12 13.3 0.0 0.2 12.5 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold adh_short_C2 PF13561.6 KXH64247.1 - 1.6e-21 76.9 9.4 1.7e-14 53.9 2.8 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXH64247.1 - 4.4e-16 58.9 4.3 4e-10 39.5 0.2 2.2 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 KXH64247.1 - 3.8e-06 26.9 3.4 6.5e-06 26.2 1.3 2.1 1 1 1 2 2 2 1 KR domain Sacchrp_dh_NADP PF03435.18 KXH64247.1 - 0.00013 22.2 1.5 0.00028 21.2 0.2 2.1 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain ApbA PF02558.16 KXH64247.1 - 0.003 17.2 0.2 0.0052 16.4 0.2 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA DAO PF01266.24 KXH64247.1 - 0.0093 15.6 6.0 0.17 11.4 4.9 2.2 1 1 1 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXH64247.1 - 0.034 13.4 2.4 0.056 12.7 2.1 1.6 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 3Beta_HSD PF01073.19 KXH64247.1 - 0.056 12.4 0.1 0.085 11.8 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family F420_oxidored PF03807.17 KXH64247.1 - 0.1 13.2 5.3 0.092 13.3 0.8 2.7 2 2 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Mg_trans_NIPA PF05653.14 KXH64249.1 - 2.4e-90 302.6 22.9 3.3e-90 302.2 22.9 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 KXH64249.1 - 1.4e-05 25.3 7.0 1.4e-05 25.3 7.0 3.1 3 0 0 3 3 3 1 EamA-like transporter family SLC35F PF06027.12 KXH64249.1 - 2.1 7.8 15.1 5.7 6.3 13.6 2.2 1 1 1 2 2 2 0 Solute carrier family 35 DUF1929 PF09118.11 KXH64250.1 - 5.3e-26 90.7 0.3 3.1e-25 88.3 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1929) WSC PF01822.19 KXH64250.1 - 8.4e-24 83.6 25.4 4.6e-13 49.2 11.7 2.7 2 0 0 2 2 2 2 WSC domain Kelch_6 PF13964.6 KXH64250.1 - 1e-11 44.7 3.4 0.00012 22.2 0.0 4.8 5 0 0 5 5 5 3 Kelch motif Kelch_2 PF07646.15 KXH64250.1 - 1.5e-08 34.2 0.9 0.28 11.2 0.1 4.9 4 0 0 4 4 4 3 Kelch motif Glyoxal_oxid_N PF07250.11 KXH64250.1 - 1.3e-06 27.8 0.1 0.02 14.1 0.1 2.5 2 0 0 2 2 2 2 Glyoxal oxidase N-terminus Kelch_1 PF01344.25 KXH64250.1 - 4.2e-06 26.2 10.6 0.00063 19.3 0.0 4.6 4 2 0 4 4 4 2 Kelch motif Kelch_4 PF13418.6 KXH64250.1 - 1.3e-05 25.1 8.4 0.2 11.7 0.0 5.1 4 1 0 4 4 4 2 Galactose oxidase, central domain Dioxygenase_C PF00775.21 KXH64251.1 - 0.00015 21.2 0.1 0.00045 19.7 0.1 1.8 1 1 0 1 1 1 1 Dioxygenase OPT PF03169.15 KXH64252.1 - 8.6e-114 381.4 43.8 4.2e-81 273.4 31.3 2.0 1 1 1 2 2 2 2 OPT oligopeptide transporter protein HET PF06985.11 KXH64253.1 - 6.7e-32 110.8 0.4 1.2e-31 110.0 0.4 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Beta_helix PF13229.6 KXH64257.1 - 0.00028 20.8 22.1 0.025 14.4 12.9 2.3 1 1 1 2 2 2 2 Right handed beta helix region Methylase_S PF01420.19 KXH64257.1 - 0.22 11.7 0.0 0.46 10.7 0.0 1.5 1 0 0 1 1 1 0 Type I restriction modification DNA specificity domain Sugar_tr PF00083.24 KXH64258.1 - 9.6e-07 28.0 0.8 0.0018 17.2 0.0 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter CcmD PF04995.14 KXH64259.1 - 0.0031 17.5 1.7 0.01 15.9 1.7 1.9 1 0 0 1 1 1 1 Heme exporter protein D (CcmD) TMEM100 PF16311.5 KXH64259.1 - 0.036 13.6 0.3 0.061 12.9 0.3 1.4 1 0 0 1 1 1 0 Transmembrane protein 100 Glyco_tranf_2_3 PF13641.6 KXH64260.1 - 3.4e-20 72.9 0.2 4.6e-20 72.5 0.2 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 KXH64260.1 - 3.4e-08 33.2 0.3 1.1e-07 31.5 0.3 1.8 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 KXH64260.1 - 3e-07 30.4 0.0 4.2e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_5 PF13712.6 KXH64260.1 - 0.014 15.1 0.0 0.032 13.9 0.0 1.6 2 0 0 2 2 2 0 Glycosyltransferase like family Ceramidase PF05875.12 KXH64261.1 - 8.4e-59 199.1 9.3 1e-58 198.8 9.3 1.0 1 0 0 1 1 1 1 Ceramidase SID-1_RNA_chan PF13965.6 KXH64261.1 - 0.12 10.8 0.8 0.17 10.3 0.8 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 F-box-like PF12937.7 KXH64262.1 - 0.0047 16.8 2.1 0.012 15.5 0.1 2.5 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KXH64263.1 - 0.0012 18.6 0.0 0.0031 17.4 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KXH64263.1 - 0.029 14.3 0.0 0.066 13.1 0.0 1.6 1 0 0 1 1 1 0 F-box-like RabGAP-TBC PF00566.18 KXH64267.1 - 3.1e-14 53.1 0.0 1.9e-11 44.1 0.0 2.4 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Stk19 PF10494.9 KXH64281.1 - 6.1e-83 278.3 0.0 7.2e-83 278.0 0.0 1.0 1 0 0 1 1 1 1 Serine-threonine protein kinase 19 zf-C2H2 PF00096.26 KXH64287.1 - 0.31 11.6 1.3 0.49 10.9 0.2 2.0 2 0 0 2 2 2 0 Zinc finger, C2H2 type FOXP-CC PF16159.5 KXH64287.1 - 0.52 11.0 2.7 0.37 11.5 0.5 2.0 2 0 0 2 2 2 0 FOXP coiled-coil domain TAF4 PF05236.14 KXH64287.1 - 1.1 9.0 7.9 0.082 12.6 2.8 1.7 2 0 0 2 2 2 0 Transcription initiation factor TFIID component TAF4 family YabA PF06156.13 KXH64287.1 - 8.1 7.1 6.1 3.9 8.1 0.2 2.2 1 1 1 2 2 2 0 Initiation control protein YabA TGT PF01702.18 KXH64291.1 - 3.3e-138 460.6 0.0 3.9e-138 460.4 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Mit_ribos_Mrp51 PF11709.8 KXH64292.1 - 2.4e-130 435.4 0.0 2.9e-130 435.1 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit Ribosomal_S17e PF00833.18 KXH64293.1 - 3.4e-59 198.1 0.2 4.2e-59 197.8 0.2 1.0 1 0 0 1 1 1 1 Ribosomal S17 RPAP2_Rtr1 PF04181.13 KXH64294.1 - 5.5e-23 81.1 0.1 1.1e-22 80.1 0.1 1.5 1 0 0 1 1 1 1 Rtr1/RPAP2 family SH3_1 PF00018.28 KXH64295.1 - 3.6e-08 32.9 0.1 3.6e-08 32.9 0.1 2.0 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 KXH64295.1 - 8.9e-07 28.5 0.0 1.6e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KXH64295.1 - 2e-06 27.6 0.1 4.3e-06 26.5 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain DNase-RNase PF02577.14 KXH64295.1 - 0.13 11.9 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 Bifunctional nuclease MCM PF00493.23 KXH64303.1 - 9.8e-106 351.9 0.3 7e-105 349.1 0.1 2.0 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 KXH64303.1 - 1.3e-36 125.2 0.1 2.4e-36 124.3 0.1 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KXH64303.1 - 1.4e-27 96.0 1.7 3.5e-27 94.7 1.7 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KXH64303.1 - 5.5e-16 59.0 1.3 1.4e-15 57.8 1.3 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KXH64303.1 - 1.6e-06 27.7 0.0 0.00023 20.6 0.0 2.4 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KXH64303.1 - 2e-05 24.6 0.0 4.5e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KXH64303.1 - 0.00043 20.1 0.0 0.0018 18.1 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KXH64303.1 - 0.057 13.1 0.0 1.2 8.9 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain DNA_RNApol_7kD PF03604.13 KXH64303.1 - 0.16 11.6 0.5 15 5.4 0.0 2.6 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit Vps54 PF07928.12 KXH64304.1 - 1.1e-51 174.8 1.8 8.4e-51 171.9 0.0 3.1 4 0 0 4 4 4 1 Vps54-like protein Vps54_N PF10475.9 KXH64304.1 - 4.4e-06 26.2 0.8 1.2e-05 24.8 0.8 1.6 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex DUF2451 PF10474.9 KXH64304.1 - 0.00016 21.5 0.0 0.00047 20.0 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function C-terminus (DUF2451) Sec8_exocyst PF04048.14 KXH64304.1 - 0.11 12.4 0.4 0.68 9.8 0.2 2.4 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain Tn7_Tnp_TnsA_C PF08721.11 KXH64304.1 - 0.11 13.1 0.5 49 4.7 0.1 4.6 4 0 0 4 4 4 0 TnsA endonuclease C terminal DUF296 PF03479.15 KXH64304.1 - 0.12 12.8 0.0 0.49 10.8 0.0 2.0 2 0 0 2 2 2 0 Plants and Prokaryotes Conserved (PCC) domain COG5 PF10392.9 KXH64304.1 - 1.5 9.0 5.4 15 5.7 1.3 2.9 2 0 0 2 2 2 0 Golgi transport complex subunit 5 COG2 PF06148.11 KXH64304.1 - 1.9 8.6 5.4 0.55 10.3 1.0 2.4 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 ANAPC8 PF04049.13 KXH64307.1 - 2.7e-46 157.1 0.6 6.6e-46 155.8 0.0 1.9 2 0 0 2 2 2 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_8 PF13181.6 KXH64307.1 - 3.2e-23 80.0 7.0 6.8e-05 22.8 0.0 7.3 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 KXH64307.1 - 5.2e-22 76.7 1.5 0.00036 20.2 0.0 7.7 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_2 PF07719.17 KXH64307.1 - 3.7e-16 57.9 15.0 0.075 13.2 0.0 8.8 9 0 0 9 9 8 5 Tetratricopeptide repeat TPR_14 PF13428.6 KXH64307.1 - 5.1e-11 42.4 11.5 0.0056 17.4 0.1 8.2 7 2 1 8 8 7 2 Tetratricopeptide repeat TPR_11 PF13414.6 KXH64307.1 - 1.9e-08 33.8 0.2 1.1e-06 28.2 0.1 3.1 3 0 0 3 3 3 1 TPR repeat TPR_16 PF13432.6 KXH64307.1 - 1.9e-08 34.8 3.1 2.5e-05 24.8 0.0 5.7 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_12 PF13424.6 KXH64307.1 - 9.6e-06 25.8 16.9 0.5 10.7 0.1 7.2 6 1 1 7 7 7 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KXH64307.1 - 1.7e-05 25.0 6.2 0.087 13.1 0.3 5.4 4 1 2 6 6 6 1 Anaphase-promoting complex, cyclosome, subunit 3 DUF3856 PF12968.7 KXH64307.1 - 0.00035 20.7 0.7 0.039 14.0 0.1 3.1 1 1 1 2 2 2 1 Domain of Unknown Function (DUF3856) TPR_7 PF13176.6 KXH64307.1 - 0.00076 19.3 9.2 0.2 11.8 0.0 5.5 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 KXH64307.1 - 0.0016 18.9 10.1 21 6.0 0.0 6.9 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_19 PF14559.6 KXH64307.1 - 0.002 18.6 10.2 6 7.5 0.0 6.8 8 1 1 9 9 8 2 Tetratricopeptide repeat TPR_17 PF13431.6 KXH64307.1 - 0.0049 17.2 0.0 6.9 7.3 0.0 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 KXH64307.1 - 0.012 15.7 9.3 2.2 8.5 0.3 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat Say1_Mug180 PF10340.9 KXH64307.1 - 0.11 11.3 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 Steryl acetyl hydrolase ChAPs PF09295.10 KXH64307.1 - 0.15 11.0 0.0 2.2 7.2 0.0 2.1 2 0 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_10 PF13374.6 KXH64307.1 - 2.4 8.1 6.4 57 3.8 0.1 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat Sel1 PF08238.12 KXH64307.1 - 4.3 8.2 10.1 1.1e+02 3.7 0.0 5.5 6 0 0 6 6 5 0 Sel1 repeat polyprenyl_synt PF00348.17 KXH64308.1 - 2.3e-90 302.1 0.0 3.1e-90 301.7 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase PH PF00169.29 KXH64309.1 - 0.0018 18.8 0.4 0.0036 17.8 0.4 1.4 1 0 0 1 1 1 1 PH domain DUF4207 PF13904.6 KXH64309.1 - 0.006 16.3 10.8 0.022 14.5 10.8 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4207) DUF5523 PF17661.1 KXH64309.1 - 0.82 9.3 10.0 1.6 8.4 10.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5523) CSN5_C PF18323.1 KXH64309.1 - 3.6 8.6 6.1 1e+02 3.9 0.0 2.8 2 0 0 2 2 2 0 Cop9 signalosome subunit 5 C-terminal domain RmlD_sub_bind PF04321.17 KXH64310.1 - 5.7e-55 186.4 0.0 6.8e-55 186.2 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 KXH64310.1 - 1.3e-20 73.9 0.0 1.6e-20 73.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KXH64310.1 - 1.4e-11 44.0 0.0 7.9e-10 38.3 0.0 2.2 2 0 0 2 2 2 1 Male sterility protein GDP_Man_Dehyd PF16363.5 KXH64310.1 - 1.9e-09 37.4 0.0 3.9e-09 36.4 0.0 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KXH64310.1 - 5.9e-08 32.0 0.0 2e-07 30.3 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KXH64310.1 - 2.2e-06 27.0 0.1 0.00034 19.9 0.0 2.9 1 1 1 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.10 KXH64310.1 - 0.16 11.9 0.5 16 5.3 0.1 2.3 1 1 1 2 2 2 0 KR domain FAD_binding_4 PF01565.23 KXH64312.1 - 3.8e-24 85.0 1.1 7.9e-24 84.0 1.1 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KXH64312.1 - 6.3e-06 26.2 0.2 1.4e-05 25.1 0.2 1.6 1 0 0 1 1 1 1 Berberine and berberine like TPR_2 PF07719.17 KXH64313.1 - 3.8e-08 32.8 0.6 0.15 12.3 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 KXH64313.1 - 1.5e-06 27.8 0.0 0.0011 18.7 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 KXH64313.1 - 0.00037 20.9 0.0 0.21 12.1 0.0 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 KXH64313.1 - 0.0023 18.6 6.8 3 8.9 0.0 4.6 2 1 2 4 4 4 2 Tetratricopeptide repeat SesA PF17107.5 KXH64313.1 - 0.011 15.9 0.2 0.048 13.9 0.1 2.2 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases TPR_16 PF13432.6 KXH64313.1 - 0.021 15.5 12.4 6.1 7.6 0.6 4.4 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 KXH64313.1 - 0.038 14.2 0.0 20 5.7 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF4472 PF14739.6 KXH64313.1 - 0.053 14.3 0.0 0.14 12.9 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4472) TPR_9 PF13371.6 KXH64313.1 - 0.1 12.8 2.6 0.15 12.3 0.3 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TOBE_2 PF08402.10 KXH64313.1 - 0.11 12.7 0.1 0.26 11.5 0.1 1.6 1 0 0 1 1 1 0 TOBE domain TPR_12 PF13424.6 KXH64313.1 - 0.79 10.1 6.0 4 7.8 0.1 3.6 3 1 0 3 3 3 0 Tetratricopeptide repeat SKIP_SNW PF02731.15 KXH64314.1 - 8.2e-72 240.1 5.3 8.2e-72 240.1 5.3 2.5 3 0 0 3 3 3 1 SKIP/SNW domain Nucleo_P87 PF07267.11 KXH64314.1 - 3 6.6 9.6 5.9 5.6 9.6 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 zf-HIT PF04438.16 KXH64315.1 - 0.2 11.6 0.3 0.39 10.6 0.3 1.4 1 0 0 1 1 1 0 HIT zinc finger Mobilization_B PF17511.2 KXH64315.1 - 0.31 11.4 1.4 0.7 10.3 1.4 1.5 1 0 0 1 1 1 0 Mobilization protein B Tim17 PF02466.19 KXH64316.1 - 2.1e-37 127.9 7.2 2.8e-37 127.5 7.2 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF543 PF04418.12 KXH64316.1 - 0.029 14.4 0.2 0.43 10.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF543) Gly-zipper_Omp PF13488.6 KXH64316.1 - 8 6.6 13.7 0.071 13.1 3.7 2.6 3 0 0 3 3 3 0 Glycine zipper USP7_ICP0_bdg PF12436.8 KXH64317.1 - 1.7e-87 292.7 0.1 5.1e-86 287.9 0.1 2.3 2 0 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.6 KXH64317.1 - 6.1e-80 267.8 4.1 1.5e-74 250.1 3.3 4.1 3 1 0 3 3 3 2 Ubiquitin-specific protease C-terminal UCH PF00443.29 KXH64317.1 - 6.8e-47 160.1 2.6 1.1e-46 159.5 2.6 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KXH64317.1 - 1e-19 71.3 0.2 2.6e-19 70.0 0.2 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.26 KXH64317.1 - 7.9e-11 42.1 0.1 6.9e-10 39.1 0.0 2.6 2 1 1 3 3 3 1 MATH domain BCDHK_Adom3 PF10436.9 KXH64318.1 - 5.9e-48 162.8 0.1 1.1e-47 161.8 0.1 1.5 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KXH64318.1 - 3.3e-07 30.8 0.0 1.3e-06 28.8 0.0 1.9 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KXH64318.1 - 0.0049 16.7 0.0 0.01 15.7 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Septin PF00735.18 KXH64319.1 - 6.9e-114 379.9 0.2 1e-113 379.3 0.2 1.3 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 KXH64319.1 - 2.6e-07 30.7 0.0 5.4e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KXH64319.1 - 7.1e-06 26.0 1.6 3.1e-05 23.9 0.0 2.6 3 0 0 3 3 3 1 RsgA GTPase GTP_EFTU PF00009.27 KXH64319.1 - 1.2e-05 24.9 4.2 7.7e-05 22.3 0.1 2.8 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 KXH64319.1 - 0.002 18.4 0.8 0.0056 16.9 0.1 2.1 2 1 0 2 2 2 1 AAA domain Pox_A32 PF04665.12 KXH64319.1 - 0.0025 17.3 0.1 0.0052 16.3 0.1 1.5 1 0 0 1 1 1 1 Poxvirus A32 protein Roc PF08477.13 KXH64319.1 - 0.0035 17.5 0.1 0.0078 16.4 0.1 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AIG1 PF04548.16 KXH64319.1 - 0.0071 15.7 0.0 0.015 14.6 0.0 1.5 1 0 0 1 1 1 1 AIG1 family IIGP PF05049.13 KXH64319.1 - 0.0089 15.1 0.0 0.016 14.3 0.0 1.4 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) Casc1_N PF15927.5 KXH64319.1 - 0.012 15.3 11.4 0.03 14.0 11.4 1.6 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus AAA_24 PF13479.6 KXH64319.1 - 0.013 15.3 0.0 0.027 14.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain Ras PF00071.22 KXH64319.1 - 0.02 14.5 0.5 0.062 12.9 0.5 1.8 1 1 0 1 1 1 0 Ras family KAP_NTPase PF07693.14 KXH64319.1 - 0.028 13.7 0.0 0.04 13.1 0.0 1.6 1 1 0 1 1 1 0 KAP family P-loop domain AAA_16 PF13191.6 KXH64319.1 - 0.035 14.5 1.1 0.095 13.1 0.0 2.2 2 1 0 2 2 2 0 AAA ATPase domain T2SSE PF00437.20 KXH64319.1 - 0.045 12.8 0.5 0.18 10.9 0.0 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein NACHT PF05729.12 KXH64319.1 - 0.048 13.6 0.0 0.099 12.6 0.0 1.5 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 KXH64319.1 - 0.053 14.0 0.3 0.2 12.2 0.0 2.0 2 0 0 2 2 2 0 ABC transporter FOXP-CC PF16159.5 KXH64319.1 - 0.066 13.8 1.2 0.066 13.8 1.2 2.5 2 1 1 3 3 2 0 FOXP coiled-coil domain AAA_25 PF13481.6 KXH64319.1 - 0.072 12.7 0.3 0.27 10.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 KXH64319.1 - 0.081 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain PduV-EutP PF10662.9 KXH64319.1 - 0.13 12.0 0.4 8.3 6.2 0.1 2.7 1 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation RNA_helicase PF00910.22 KXH64319.1 - 0.14 12.5 0.0 0.43 11.0 0.0 1.9 2 0 0 2 2 1 0 RNA helicase Dynamin_N PF00350.23 KXH64319.1 - 0.54 10.3 7.3 4.2 7.4 0.1 3.1 2 1 1 3 3 3 0 Dynamin family FUSC PF04632.12 KXH64319.1 - 3.2 6.2 4.6 4.4 5.7 4.6 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family AAA_11 PF13086.6 KXH64319.1 - 3.8 7.2 7.5 23 4.7 0.1 2.2 2 0 0 2 2 2 0 AAA domain Myc-LZ PF02344.15 KXH64319.1 - 4.3 7.5 9.1 5.2 7.3 3.1 3.2 2 1 0 2 2 2 0 Myc leucine zipper domain WD40 PF00400.32 KXH64320.1 - 1.8e-37 126.7 29.5 1.6e-08 35.0 0.0 12.5 14 0 0 14 14 14 7 WD domain, G-beta repeat Utp12 PF04003.12 KXH64320.1 - 5.5e-24 84.5 0.0 9.7e-24 83.7 0.0 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 KXH64320.1 - 1e-19 70.6 0.0 0.012 15.9 0.0 10.0 5 2 5 11 11 11 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KXH64320.1 - 2.7e-07 29.9 1.0 0.69 8.8 0.0 5.8 4 3 2 6 6 6 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KXH64320.1 - 2.3e-05 24.4 5.7 0.075 12.9 0.2 5.7 6 1 1 7 7 7 2 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.6 KXH64320.1 - 0.0028 17.0 0.4 3.9 6.7 0.0 3.8 3 1 1 4 4 4 2 Neuroblastoma-amplified sequence, N terminal Cytochrom_D1 PF02239.16 KXH64320.1 - 0.027 13.0 0.1 1.1 7.7 0.1 3.3 1 1 2 3 3 3 0 Cytochrome D1 heme domain PD40 PF07676.12 KXH64320.1 - 0.051 13.5 0.3 30 4.7 0.0 4.3 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Nup160 PF11715.8 KXH64320.1 - 0.06 12.0 3.9 5.6 5.5 0.0 3.6 3 2 1 4 4 4 0 Nucleoporin Nup120/160 Questin_oxidase PF14027.6 KXH64321.1 - 1.2e-97 327.5 0.3 1.5e-97 327.2 0.3 1.1 1 0 0 1 1 1 1 Questin oxidase-like ACP_PD PF04336.12 KXH64321.1 - 0.071 13.5 0.2 0.071 13.5 0.2 2.0 2 0 0 2 2 2 0 Acyl carrier protein phosphodiesterase Kelch_5 PF13854.6 KXH64322.1 - 6.6e-14 51.5 4.3 3.6e-11 42.8 0.3 3.6 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.6 KXH64322.1 - 0.00077 19.7 9.2 0.087 13.2 0.2 4.4 5 0 0 5 5 5 2 Kelch motif Kelch_4 PF13418.6 KXH64322.1 - 0.0024 17.8 15.0 0.03 14.3 0.3 5.2 6 0 0 6 6 6 3 Galactose oxidase, central domain Ntox21 PF15526.6 KXH64322.1 - 0.095 13.0 0.2 0.44 10.9 0.2 2.1 1 1 0 1 1 1 0 Novel toxin 21 Kelch_2 PF07646.15 KXH64322.1 - 0.14 12.2 8.6 7 6.8 0.0 4.6 5 0 0 5 5 5 0 Kelch motif NAP PF00956.18 KXH64323.1 - 1.7e-29 102.8 2.6 1.1e-26 93.6 0.1 2.3 1 1 1 2 2 2 2 Nucleosome assembly protein (NAP) CENP-B_dimeris PF09026.10 KXH64323.1 - 7.7 7.0 17.3 5.3 7.5 3.0 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Zn_clus PF00172.18 KXH64324.1 - 3.8e-09 36.5 12.8 6.8e-09 35.7 12.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KXH64324.1 - 5.4e-06 25.5 0.1 1.1e-05 24.5 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Peptidase_S8 PF00082.22 KXH64325.1 - 4.9e-22 78.6 3.7 1.4e-21 77.1 3.7 1.6 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 KXH64325.1 - 2.1e-08 34.7 0.0 4.9e-08 33.5 0.0 1.7 1 0 0 1 1 1 1 Peptidase inhibitor I9 zf-rbx1 PF12678.7 KXH64326.1 - 4.9e-10 39.5 0.6 9e-10 38.7 0.6 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KXH64326.1 - 6e-08 32.9 2.2 6e-08 32.9 2.2 2.1 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 KXH64326.1 - 6.9e-07 29.0 0.5 1.1e-06 28.3 0.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXH64326.1 - 1.7e-06 27.8 1.4 3.8e-06 26.8 1.4 1.6 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KXH64326.1 - 3.9e-06 26.8 1.4 5.1e-05 23.2 0.1 3.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KXH64326.1 - 7.8e-06 25.6 6.2 2.3e-05 24.1 1.8 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KXH64326.1 - 1.7e-05 24.6 0.7 3.5e-05 23.6 0.7 1.5 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 KXH64326.1 - 0.00018 21.3 1.2 0.00018 21.3 1.2 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DUF2921 PF11145.8 KXH64326.1 - 0.00089 17.2 0.9 0.0013 16.7 0.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2921) Zn_ribbon_17 PF17120.5 KXH64326.1 - 0.0054 16.3 0.7 0.013 15.1 0.7 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 KXH64326.1 - 0.0076 16.0 0.6 0.0076 16.0 0.6 3.2 3 0 0 3 3 3 1 RING-like zinc finger zf-ANAPC11 PF12861.7 KXH64326.1 - 0.018 15.1 0.9 0.047 13.8 0.9 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger HSBP1 PF06825.12 KXH64327.1 - 1.1e-15 57.1 0.2 1.5e-15 56.8 0.2 1.1 1 0 0 1 1 1 1 Heat shock factor binding protein 1 Baculo_PEP_C PF04513.12 KXH64327.1 - 0.024 14.7 0.1 0.03 14.4 0.1 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DASH_Spc19 PF08287.11 KXH64327.1 - 0.056 13.3 0.0 0.075 12.9 0.0 1.1 1 0 0 1 1 1 0 Spc19 CheX PF13690.6 KXH64327.1 - 0.08 13.1 0.0 0.091 12.9 0.0 1.2 1 0 0 1 1 1 0 Chemotaxis phosphatase CheX Thioredoxin PF00085.20 KXH64328.1 - 4.3e-57 190.5 0.0 2.1e-29 101.5 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.12 KXH64328.1 - 3.9e-27 95.0 2.0 6.9e-27 94.2 0.9 2.0 2 0 0 2 2 2 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.6 KXH64328.1 - 7.9e-15 55.2 0.0 4e-07 30.5 0.0 3.0 2 0 0 2 2 2 2 Thioredoxin-like domain OST3_OST6 PF04756.13 KXH64328.1 - 1.8e-13 50.5 0.0 3.4e-06 26.6 0.0 2.1 1 1 1 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 KXH64328.1 - 6.2e-08 32.7 0.7 0.0024 18.0 0.0 2.8 3 0 0 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.21 KXH64328.1 - 1.8e-07 31.1 0.0 0.0016 18.4 0.0 2.4 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_8 PF13905.6 KXH64328.1 - 6.2e-07 29.7 0.0 0.0024 18.2 0.0 3.1 2 1 1 3 3 3 2 Thioredoxin-like TraF PF13728.6 KXH64328.1 - 7.5e-05 22.6 0.0 0.39 10.5 0.0 2.5 2 0 0 2 2 2 2 F plasmid transfer operon protein Redoxin PF08534.10 KXH64328.1 - 8.9e-05 22.2 0.1 0.024 14.3 0.0 2.4 2 0 0 2 2 2 2 Redoxin HyaE PF07449.11 KXH64328.1 - 0.0006 19.8 0.0 0.022 14.7 0.0 2.5 2 0 0 2 2 2 1 Hydrogenase-1 expression protein HyaE Thioredoxin_9 PF14595.6 KXH64328.1 - 0.0011 18.8 0.0 0.67 9.7 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin ERp29_N PF07912.13 KXH64328.1 - 0.0014 18.8 0.6 0.0044 17.2 0.0 2.1 3 0 0 3 3 3 1 ERp29, N-terminal domain Thioredoxin_4 PF13462.6 KXH64328.1 - 0.013 15.7 1.1 13 5.9 0.1 3.7 3 2 1 4 4 4 0 Thioredoxin Glutaredoxin PF00462.24 KXH64328.1 - 0.013 15.7 0.2 3.6 7.9 0.0 2.9 2 1 0 2 2 2 0 Glutaredoxin Ribosomal_S14 PF00253.21 KXH64329.1 - 4.9e-15 55.0 3.3 6.3e-15 54.7 3.3 1.2 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e ZZ PF00569.17 KXH64329.1 - 0.3 11.0 4.2 3.1 7.7 4.2 2.2 1 1 0 1 1 1 0 Zinc finger, ZZ type GTP_EFTU PF00009.27 KXH64330.1 - 4.6e-57 192.7 0.2 6.3e-57 192.3 0.2 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KXH64330.1 - 1.8e-26 92.6 0.1 4.8e-26 91.3 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KXH64330.1 - 1.6e-15 57.2 2.3 1.6e-15 57.2 2.3 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KXH64330.1 - 1.4e-05 25.1 0.1 2.8e-05 24.2 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KXH64330.1 - 0.00095 19.1 0.0 0.003 17.5 0.0 1.9 2 0 0 2 2 2 1 RsgA GTPase cobW PF02492.19 KXH64330.1 - 0.023 14.3 0.3 0.14 11.7 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 KXH64330.1 - 0.085 12.6 0.2 15 5.3 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF2011 PF09428.10 KXH64331.1 - 9.7e-21 73.8 0.0 2.6e-20 72.4 0.0 1.8 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2011) Cyclin PF08613.11 KXH64366.1 - 8.7e-41 140.0 7.6 1.4e-24 87.3 0.1 2.7 3 0 0 3 3 3 2 Cyclin FAM176 PF14851.6 KXH64366.1 - 0.2 11.3 1.9 10 5.8 1.7 2.4 2 0 0 2 2 2 0 FAM176 family Hamartin PF04388.12 KXH64366.1 - 1.1 7.8 15.5 1.7 7.2 15.5 1.2 1 0 0 1 1 1 0 Hamartin protein DHQ_synthase PF01761.20 KXH64381.1 - 1.3e-39 136.0 0.0 2e-39 135.4 0.0 1.2 1 0 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.6 KXH64381.1 - 0.0045 16.7 0.0 0.0074 16.0 0.0 1.3 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Methyltransf_3 PF01596.17 KXH64382.1 - 1e-11 44.4 0.0 1.3e-11 44.0 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 KXH64382.1 - 2.9e-09 37.9 0.0 4.9e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DUF5122 PF17164.4 KXH64382.1 - 0.13 12.6 0.0 0.29 11.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5122) beta-propeller Mito_carr PF00153.27 KXH64383.1 - 1.2e-60 201.4 4.4 2.3e-22 78.7 0.1 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KXH64383.1 - 0.12 11.5 0.0 4.2 6.4 0.0 2.5 2 1 0 2 2 2 0 Gammaproteobacterial serine protease MT-A70 PF05063.14 KXH64384.1 - 3.6e-33 114.9 0.0 5.1e-33 114.4 0.0 1.2 1 0 0 1 1 1 1 MT-A70 Renin_r PF07850.14 KXH64390.1 - 0.98 10.1 2.7 14 6.4 0.1 2.8 2 1 1 3 3 3 0 Renin receptor-like protein SAP PF02037.27 KXH64391.1 - 1.3e-12 47.2 0.7 2.7e-12 46.1 0.7 1.6 1 0 0 1 1 1 1 SAP domain PseudoU_synth_2 PF00849.22 KXH64413.1 - 8e-33 113.8 0.0 1.1e-32 113.3 0.0 1.2 1 0 0 1 1 1 1 RNA pseudouridylate synthase Ub-Mut7C PF14451.6 KXH64413.1 - 0.0019 18.0 0.1 0.0044 16.8 0.1 1.6 1 0 0 1 1 1 1 Mut7-C ubiquitin DnaB_bind PF10410.9 KXH64413.1 - 0.12 12.5 0.0 0.32 11.2 0.0 1.7 1 0 0 1 1 1 0 DnaB-helicase binding domain of primase PAD_porph PF04371.15 KXH64413.1 - 0.12 11.6 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Porphyromonas-type peptidyl-arginine deiminase 4HBT PF03061.22 KXH64414.1 - 2.2e-06 27.9 0.0 3.2e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily Acyl-ACP_TE PF01643.17 KXH64414.1 - 2.1e-05 23.9 1.0 2.5e-05 23.7 1.0 1.3 1 1 0 1 1 1 1 Acyl-ACP thioesterase 4HBT_2 PF13279.6 KXH64414.1 - 3.3e-05 24.3 0.0 4.2e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Epsilon_antitox PF08998.11 KXH64414.1 - 0.079 13.2 0.3 0.76 10.1 0.0 2.1 2 0 0 2 2 2 0 Bacterial epsilon antitoxin GFO_IDH_MocA PF01408.22 KXH64415.1 - 5.3e-19 69.2 0.0 8.9e-19 68.5 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KXH64415.1 - 0.015 15.3 0.0 0.025 14.6 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain MatE PF01554.18 KXH64416.1 - 3.2e-52 176.4 20.8 2.8e-26 92.1 9.3 2.3 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 KXH64416.1 - 0.00027 21.0 14.0 0.00027 21.0 14.0 4.4 3 2 0 3 3 3 1 Polysaccharide biosynthesis C-terminal domain Fungal_trans_2 PF11951.8 KXH64417.1 - 3.3e-11 42.6 0.1 1.3e-10 40.7 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Patatin PF01734.22 KXH64418.1 - 1.4e-15 58.0 0.0 4.4e-15 56.4 0.0 1.8 1 1 0 1 1 1 1 Patatin-like phospholipase zf-C2H2 PF00096.26 KXH64419.1 - 0.011 16.1 19.8 0.1 13.1 0.8 4.7 4 1 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXH64419.1 - 0.027 15.3 19.1 0.096 13.6 0.7 5.1 4 1 0 4 4 4 0 C2H2-type zinc finger Sina PF03145.16 KXH64419.1 - 1.9 8.4 7.2 0.25 11.3 2.9 1.7 2 0 0 2 2 2 0 Seven in absentia protein family Glyco_hydro_43 PF04616.14 KXH64420.1 - 1.5e-18 67.1 5.4 2.7e-18 66.3 5.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_31 PF01055.26 KXH64421.1 - 2.2e-156 521.5 1.7 2.8e-156 521.1 1.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 KXH64421.1 - 6.9e-40 135.9 0.1 1.3e-39 135.0 0.1 1.4 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 KXH64421.1 - 1.1e-14 54.5 4.1 2.1e-14 53.6 1.6 2.8 3 0 0 3 3 3 1 Galactose mutarotase-like DUF4763 PF15960.5 KXH64423.1 - 0.058 12.7 0.2 0.058 12.7 0.2 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4763) V_ATPase_I PF01496.19 KXH64423.1 - 3.6 5.4 8.9 2.2 6.1 2.3 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family AA_permease PF00324.21 KXH64424.1 - 1.5e-101 340.4 34.3 1.8e-101 340.1 34.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KXH64424.1 - 7.5e-34 117.3 39.8 9.1e-34 117.0 39.8 1.0 1 0 0 1 1 1 1 Amino acid permease zf-UBR PF02207.20 KXH64425.1 - 4.4e-14 52.4 5.3 4.4e-14 52.4 5.3 3.3 4 0 0 4 4 4 1 Putative zinc finger in N-recognin (UBR box) DEC-1_N PF04625.13 KXH64425.1 - 0.42 9.6 6.3 0.93 8.4 6.2 1.7 1 1 0 1 1 1 0 DEC-1 protein, N-terminal region DHODB_Fe-S_bind PF10418.9 KXH64425.1 - 7.1 6.5 10.0 0.85 9.5 3.9 2.7 3 0 0 3 3 3 0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B MCM PF00493.23 KXH64426.1 - 1.7e-99 331.5 0.6 2.4e-99 331.0 0.0 1.6 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 KXH64426.1 - 7.7e-39 132.4 0.1 1.5e-38 131.5 0.1 1.5 1 0 0 1 1 1 1 MCM OB domain MCM2_N PF12619.8 KXH64426.1 - 2.8e-32 112.1 33.2 2.8e-32 112.1 33.2 2.5 3 0 0 3 3 3 1 Mini-chromosome maintenance protein 2 MCM_lid PF17855.1 KXH64426.1 - 3.9e-26 91.3 1.1 1.2e-25 89.8 1.1 1.9 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KXH64426.1 - 9.2e-14 51.9 1.1 1.5e-13 51.2 0.2 1.9 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 KXH64426.1 - 8.4e-08 31.8 0.0 5.9e-06 25.8 0.0 2.7 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KXH64426.1 - 1.8e-06 28.0 0.0 4.5e-06 26.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KXH64426.1 - 0.003 17.4 0.1 0.014 15.2 0.0 2.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KXH64426.1 - 0.0035 17.1 0.2 0.024 14.3 0.2 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain Zn_ribbon_2 PF12674.7 KXH64426.1 - 0.063 13.9 0.5 0.19 12.4 0.5 1.8 1 0 0 1 1 1 0 Putative zinc ribbon domain zf-TFIIB PF13453.6 KXH64426.1 - 0.12 11.7 1.7 0.28 10.6 1.7 1.6 1 0 0 1 1 1 0 Transcription factor zinc-finger Zn_clus PF00172.18 KXH64429.1 - 3.5 7.8 6.9 8.6 6.6 6.9 1.7 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Ni_hydr_CYTB PF01292.20 KXH64430.1 - 0.023 14.3 0.0 0.023 14.3 0.0 1.1 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 MFS_MOT1 PF16983.5 KXH64431.1 - 4.6e-64 213.7 27.8 5.1e-35 120.2 11.0 2.5 2 0 0 2 2 2 2 Molybdate transporter of MFS superfamily Sulfate_transp PF00916.20 KXH64431.1 - 0.01 14.6 17.2 0.22 10.2 17.2 2.3 1 1 0 1 1 1 0 Sulfate permease family Forkhead PF00250.18 KXH64432.1 - 1.6e-14 53.9 0.0 3.3e-14 52.9 0.0 1.5 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 KXH64432.1 - 4.2e-05 23.8 0.1 8.5e-05 22.8 0.1 1.5 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KXH64432.1 - 0.11 12.9 0.0 0.28 11.5 0.0 1.7 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain TMEM154 PF15102.6 KXH64433.1 - 0.00022 21.1 5.6 0.00069 19.5 5.6 1.8 1 1 0 1 1 1 1 TMEM154 protein family EphA2_TM PF14575.6 KXH64433.1 - 0.00091 20.1 0.0 0.0018 19.1 0.0 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain DUF5305 PF17231.2 KXH64433.1 - 0.0012 18.3 3.3 0.002 17.6 3.3 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5305) RCR PF12273.8 KXH64433.1 - 0.0078 16.9 0.4 0.047 14.4 0.0 2.0 2 0 0 2 2 2 1 Chitin synthesis regulation, resistance to Congo red Amnionless PF14828.6 KXH64433.1 - 0.012 14.5 0.1 0.013 14.3 0.1 1.1 1 0 0 1 1 1 0 Amnionless TrkH PF02386.16 KXH64433.1 - 0.018 13.5 1.3 0.023 13.2 1.3 1.0 1 0 0 1 1 1 0 Cation transport protein T4SS_CagC PF16943.5 KXH64433.1 - 0.024 14.8 0.0 0.048 13.8 0.0 1.4 1 0 0 1 1 1 0 Cag pathogenicity island, type IV secretory system SKG6 PF08693.10 KXH64433.1 - 0.03 13.7 3.7 0.066 12.6 3.7 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Beta-APP PF03494.13 KXH64433.1 - 0.052 13.4 4.9 0.086 12.7 4.9 1.3 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) Phage_holin_2_1 PF04971.12 KXH64433.1 - 0.11 12.5 0.9 0.22 11.6 0.9 1.7 1 1 0 1 1 1 0 Bacteriophage P21 holin S DUF2163 PF09931.9 KXH64433.1 - 0.18 12.0 0.8 0.23 11.7 0.8 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2163) SARAF PF06682.12 KXH64433.1 - 0.29 10.8 7.7 0.36 10.4 7.7 1.2 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Mucin PF01456.17 KXH64433.1 - 2.7 8.0 23.9 4.9 7.1 23.9 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein CAP59_mtransfer PF11735.8 KXH64434.1 - 1.8e-65 221.0 0.0 2.3e-65 220.7 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 MSA-2c PF12238.8 KXH64434.1 - 2.5 8.0 6.2 4 7.4 6.2 1.2 1 0 0 1 1 1 0 Merozoite surface antigen 2c Pox_Ag35 PF03286.14 KXH64435.1 - 0.22 11.3 4.8 0.34 10.7 4.8 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Methyltransf_31 PF13847.6 KXH64436.1 - 1.8e-20 73.3 0.0 2.6e-20 72.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH64436.1 - 2.5e-17 63.4 0.0 1.1e-16 61.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH64436.1 - 1.4e-15 57.7 0.0 1e-14 54.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXH64436.1 - 1.1e-14 54.3 0.0 2.3e-14 53.3 0.0 1.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KXH64436.1 - 8.3e-13 48.9 0.0 1.9e-12 47.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXH64436.1 - 5.3e-09 36.1 0.0 9.4e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KXH64436.1 - 4.2e-07 29.9 0.0 7.6e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TPMT PF05724.11 KXH64436.1 - 0.00026 20.7 0.0 0.00042 20.0 0.0 1.3 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Fibrillarin PF01269.17 KXH64436.1 - 0.0048 16.0 0.0 0.0089 15.2 0.0 1.4 1 0 0 1 1 1 1 Fibrillarin UPF0020 PF01170.18 KXH64436.1 - 0.011 15.5 0.0 0.031 14.0 0.0 1.9 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_24 PF13578.6 KXH64436.1 - 0.015 16.3 0.0 0.068 14.2 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Methyltr_RsmB-F PF01189.17 KXH64436.1 - 0.025 14.2 0.0 0.042 13.5 0.0 1.3 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F CMAS PF02353.20 KXH64436.1 - 0.033 13.5 0.0 0.13 11.5 0.0 1.8 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase FtsJ PF01728.19 KXH64436.1 - 0.063 13.4 0.0 0.63 10.1 0.0 2.2 1 1 0 1 1 1 0 FtsJ-like methyltransferase CheR PF01739.18 KXH64436.1 - 0.09 12.2 0.0 7.2 6.0 0.0 2.3 1 1 0 2 2 2 0 CheR methyltransferase, SAM binding domain N6_N4_Mtase PF01555.18 KXH64436.1 - 0.094 12.4 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 DNA methylase HAD_2 PF13419.6 KXH64437.1 - 0.00043 20.4 0.0 0.00089 19.4 0.0 1.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Phi29_Phage_SSB PF17427.2 KXH64437.1 - 0.088 13.0 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Phage Single-stranded DNA-binding protein Ribosomal_L5e PF17144.4 KXH64438.1 - 1.5e-77 259.2 0.1 1.5e-77 259.2 0.1 1.6 2 0 0 2 2 2 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 KXH64438.1 - 5.3e-35 120.2 12.6 5.3e-35 120.2 12.6 2.1 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region LRR_6 PF13516.6 KXH64439.1 - 0.3 11.2 13.8 21 5.5 0.0 6.2 7 0 0 7 7 7 0 Leucine Rich repeat Tim54 PF11711.8 KXH64439.1 - 2.4 6.9 9.9 4.9 5.8 9.9 1.5 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 RR_TM4-6 PF06459.12 KXH64439.1 - 8.7 6.1 14.1 21 4.8 14.1 1.6 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF1996 PF09362.10 KXH64440.1 - 6.9e-46 157.1 0.4 8.3e-46 156.9 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) PS_Dcarbxylase PF02666.15 KXH64441.1 - 2.5e-56 190.4 0.0 4.1e-56 189.7 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.30 KXH64441.1 - 2.6e-38 130.4 0.0 5.9e-18 65.1 0.0 2.9 3 0 0 3 3 3 2 C2 domain EF-hand_5 PF13202.6 KXH64441.1 - 0.0011 18.3 0.0 0.013 14.9 0.0 2.5 2 0 0 2 2 2 1 EF hand EF-hand_1 PF00036.32 KXH64441.1 - 0.0072 15.8 0.0 0.032 13.8 0.0 2.2 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 KXH64441.1 - 0.015 15.2 0.0 0.11 12.5 0.0 2.6 2 0 0 2 2 2 0 EF-hand domain EF-hand_7 PF13499.6 KXH64441.1 - 0.037 14.5 0.2 0.11 13.0 0.2 1.8 1 0 0 1 1 1 0 EF-hand domain pair ERp29 PF07749.12 KXH64441.1 - 0.74 10.8 3.2 1.4 9.9 0.6 2.6 2 1 1 3 3 3 0 Endoplasmic reticulum protein ERp29, C-terminal domain p450 PF00067.22 KXH64478.1 - 4.7e-66 223.4 0.0 6.5e-66 223.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.18 KXH64479.1 - 0.00011 21.3 0.2 0.00095 18.3 0.0 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain RVT_3 PF13456.6 KXH64484.1 - 0.00018 21.3 0.0 0.00021 21.1 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase-like IL32 PF15225.6 KXH64484.1 - 0.007 16.7 0.2 0.035 14.5 0.1 1.9 1 1 1 2 2 2 1 Interleukin 32 Trimer_CC PF08954.11 KXH64484.1 - 1.5 8.5 4.9 0.32 10.6 0.4 2.2 3 0 0 3 3 3 0 Trimerisation motif Aldo_ket_red PF00248.21 KXH64489.1 - 8.5e-57 192.6 0.0 1e-56 192.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family HET PF06985.11 KXH64490.1 - 3.5e-26 92.3 0.0 5.5e-26 91.7 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Aminotran_3 PF00202.21 KXH64491.1 - 1.7e-122 409.0 0.0 1.9e-122 408.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 KXH64491.1 - 0.00052 19.4 0.0 0.0011 18.3 0.0 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase DUF3543 PF12063.8 KXH64493.1 - 2.3e-89 299.1 0.2 3.4e-89 298.5 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase PF00069.25 KXH64493.1 - 2e-59 201.1 0.0 3.5e-59 200.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXH64493.1 - 2.8e-42 144.8 0.0 5e-42 144.0 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase MIT PF04212.18 KXH64493.1 - 0.0025 17.8 0.3 0.24 11.5 0.1 2.5 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain RRM_1 PF00076.22 KXH64516.1 - 4.6e-14 52.0 0.0 9e-14 51.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Asp-B-Hydro_N PF05279.11 KXH64516.1 - 3.2 7.7 24.4 5.4 7.0 24.4 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region TP53IP5 PF15331.6 KXH64516.1 - 6.6 6.8 13.5 10 6.2 13.5 1.4 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 DUF4407 PF14362.6 KXH64516.1 - 8.2 5.7 12.8 12 5.2 12.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2052 PF09747.9 KXH64516.1 - 9 6.4 21.2 20 5.2 21.2 1.6 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) HET PF06985.11 KXH64518.1 - 5.5e-12 46.3 5.4 1.6e-09 38.3 0.4 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Fmp27 PF10344.9 KXH64519.1 - 5.9e-233 775.8 0.0 1.1e-232 774.9 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial protein from FMP27 Apt1 PF10351.9 KXH64519.1 - 8.4e-199 661.3 0.9 8.4e-199 661.3 0.9 3.2 3 0 0 3 3 3 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.9 KXH64519.1 - 3.8e-181 603.2 0.0 8.4e-181 602.0 0.0 1.6 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.9 KXH64519.1 - 7e-57 191.7 0.1 2e-56 190.2 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_GFWDK PF10347.9 KXH64519.1 - 3e-56 189.9 0.0 6e-56 188.9 0.0 1.6 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Fmp27_SW PF10305.9 KXH64519.1 - 1.4e-32 112.5 0.0 1.1e-31 109.5 0.0 2.7 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain TFIIA PF03153.13 KXH64520.1 - 6.2 6.7 9.9 3.7 7.5 2.0 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit JAB PF01398.21 KXH64521.1 - 4.6e-32 110.5 0.1 7.9e-32 109.7 0.1 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease CSN5_C PF18323.1 KXH64521.1 - 9.8e-25 87.3 0.1 1.8e-24 86.5 0.1 1.4 1 0 0 1 1 1 1 Cop9 signalosome subunit 5 C-terminal domain Prok-JAB PF14464.6 KXH64521.1 - 0.00012 21.9 0.0 0.00022 21.0 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain DUF3328 PF11807.8 KXH64523.1 - 1.2e-48 165.8 0.4 1.6e-48 165.4 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) MFS_1 PF07690.16 KXH64524.1 - 1.4e-33 116.3 26.5 1.4e-33 116.3 26.5 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Trp_oprn_chp PF09534.10 KXH64524.1 - 1.2 8.9 11.4 2.3 8.0 3.5 3.1 3 0 0 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) RdRP PF05183.12 KXH64525.1 - 5.3e-181 603.2 0.0 7.3e-181 602.8 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase FAD-oxidase_C PF02913.19 KXH64525.1 - 3.2e-59 200.6 0.0 5.4e-59 199.8 0.0 1.4 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KXH64525.1 - 7e-33 113.3 0.0 1.4e-32 112.4 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain RRM_1 PF00076.22 KXH64525.1 - 1.8e-07 30.9 0.0 4.7e-05 23.1 0.0 3.6 4 0 0 4 4 4 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_S4e PF00900.20 KXH64527.1 - 7.5e-36 121.9 0.3 1.9e-35 120.6 0.1 1.8 2 0 0 2 2 2 1 Ribosomal family S4e 40S_S4_C PF16121.5 KXH64527.1 - 1.9e-24 85.0 0.1 3.7e-24 84.1 0.1 1.5 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 KXH64527.1 - 9.8e-18 64.0 4.9 1.9e-17 63.1 4.9 1.5 1 0 0 1 1 1 1 RS4NT (NUC023) domain KOW PF00467.29 KXH64527.1 - 1.4e-05 24.8 1.8 1.4e-05 24.8 1.8 3.0 3 0 0 3 3 3 1 KOW motif S4 PF01479.25 KXH64527.1 - 2.2e-05 24.0 0.0 5.1e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 S4 domain Myb_DNA-binding PF00249.31 KXH64528.1 - 1e-14 54.4 0.0 4.6e-07 29.9 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KXH64528.1 - 1.3e-09 38.2 0.0 0.00068 19.8 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 KXH64528.1 - 5.7e-05 23.1 0.5 0.15 12.1 0.0 2.6 3 0 0 3 3 3 2 SLIDE CHDCT2 PF08074.11 KXH64528.1 - 0.036 14.3 0.0 0.19 11.9 0.0 2.2 2 0 0 2 2 2 0 CHDCT2 (NUC038) domain SANT_DAMP1_like PF16282.5 KXH64528.1 - 0.1 12.8 0.0 0.25 11.5 0.0 1.6 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 Egh16-like PF11327.8 KXH64545.1 - 2.2e-67 227.1 11.2 2.8e-67 226.7 11.2 1.1 1 0 0 1 1 1 1 Egh16-like virulence factor zf-CCHC PF00098.23 KXH64546.1 - 0.00092 19.2 0.6 0.0017 18.4 0.6 1.4 1 0 0 1 1 1 1 Zinc knuckle Metallophos PF00149.28 KXH64547.1 - 3.5e-37 128.9 0.7 4.7e-37 128.5 0.7 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KXH64547.1 - 0.069 13.6 0.4 0.18 12.2 0.4 1.7 1 1 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Metallophos_2 PF12850.7 KXH64547.1 - 0.15 12.3 0.0 0.24 11.6 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Rho_GDI PF02115.17 KXH64548.1 - 1.7e-60 204.1 0.3 1.7e-60 204.1 0.3 1.9 2 0 0 2 2 2 1 RHO protein GDP dissociation inhibitor KilA-N PF04383.13 KXH64549.1 - 0.016 15.0 0.0 0.24 11.3 0.0 2.4 1 1 0 1 1 1 0 KilA-N domain NAD_binding_2 PF03446.15 KXH64550.1 - 8.1e-37 126.8 0.1 1.3e-36 126.2 0.1 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KXH64550.1 - 8.4e-29 100.3 0.0 1.4e-28 99.6 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 KXH64550.1 - 1.1e-06 29.1 0.0 3.2e-06 27.6 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent OCD_Mu_crystall PF02423.15 KXH64550.1 - 0.00013 21.0 0.0 0.00023 20.2 0.0 1.3 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family TrkA_N PF02254.18 KXH64550.1 - 0.00026 21.2 0.0 0.00048 20.4 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain Ldh_1_N PF00056.23 KXH64550.1 - 0.024 14.7 0.1 0.053 13.6 0.1 1.5 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KXH64550.1 - 0.032 14.3 0.0 0.057 13.5 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 KXH64550.1 - 0.042 13.7 0.1 0.2 11.5 0.1 2.0 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 KXH64550.1 - 0.11 13.3 0.0 0.23 12.3 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Glyco_hydro_4 PF02056.16 KXH64550.1 - 0.15 11.6 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Family 4 glycosyl hydrolase RTA1 PF04479.13 KXH64552.1 - 1.3e-71 240.5 4.8 1.8e-71 240.0 4.8 1.2 1 0 0 1 1 1 1 RTA1 like protein PGG PF13962.6 KXH64552.1 - 0.033 14.0 0.2 0.088 12.6 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function Adaptin_N PF01602.20 KXH64553.1 - 7.1e-106 354.8 0.0 8.6e-106 354.6 0.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KXH64553.1 - 8.9e-15 55.1 0.2 8.4e-14 51.9 0.0 2.7 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KXH64553.1 - 7.4e-11 42.3 3.1 0.00046 20.5 0.0 5.6 4 2 3 7 7 6 3 HEAT repeats HEAT PF02985.22 KXH64553.1 - 2.8e-09 36.4 0.4 0.03 14.6 0.0 5.9 6 0 0 6 6 6 1 HEAT repeat HEAT_EZ PF13513.6 KXH64553.1 - 0.00025 21.5 3.2 0.11 13.1 0.0 4.7 4 1 0 4 4 4 1 HEAT-like repeat Cohesin_HEAT PF12765.7 KXH64553.1 - 0.00026 21.2 1.1 0.053 13.8 0.0 3.1 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion TAP42 PF04177.12 KXH64553.1 - 0.0049 16.0 5.8 0.0085 15.3 5.8 1.3 1 0 0 1 1 1 1 TAP42-like family TFIIA PF03153.13 KXH64553.1 - 0.088 12.8 18.3 0.13 12.3 18.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit VHS PF00790.19 KXH64553.1 - 0.12 12.2 0.2 40 4.1 0.1 3.3 4 0 0 4 4 4 0 VHS domain CDC45 PF02724.14 KXH64553.1 - 0.21 9.8 19.8 0.32 9.2 19.8 1.2 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 KXH64553.1 - 0.29 10.5 23.9 0.4 10.0 23.9 1.2 1 0 0 1 1 1 0 SDA1 Cwf_Cwc_15 PF04889.12 KXH64553.1 - 0.48 10.1 19.0 0.71 9.6 19.0 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.12 KXH64553.1 - 1.8 6.7 28.4 2.3 6.3 28.4 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 KXH64553.1 - 1.8 7.8 20.1 2.6 7.3 20.1 1.2 1 0 0 1 1 1 0 BUD22 DUF913 PF06025.12 KXH64553.1 - 7.1 5.5 6.2 36 3.2 7.4 1.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) Nuf2 PF03800.14 KXH64555.1 - 2.7e-42 144.2 0.0 7.5e-42 142.7 0.0 1.8 1 0 0 1 1 1 1 Nuf2 family DHR10 PF18595.1 KXH64555.1 - 9.9e-37 125.6 17.2 9.9e-37 125.6 17.2 3.9 3 1 0 3 3 3 1 Designed helical repeat protein 10 domain Troponin PF00992.20 KXH64555.1 - 2.5 8.4 45.4 2 8.7 16.5 3.4 2 2 1 3 3 3 0 Troponin TetR_C_13 PF16925.5 KXH64555.1 - 8.8 6.3 7.7 3.9 7.4 1.0 2.7 2 1 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain RFXA_RFXANK_bdg PF15289.6 KXH64556.1 - 0.0081 16.5 1.0 0.036 14.4 1.0 2.2 1 0 0 1 1 1 1 Regulatory factor X-associated C-terminal binding domain Trypan_PARP PF05887.11 KXH64556.1 - 0.77 9.7 9.1 3.2 7.7 9.1 2.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) HET PF06985.11 KXH64557.1 - 1e-10 42.1 4.0 2.4e-07 31.2 0.5 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) GluR_Homer-bdg PF10606.9 KXH64557.1 - 0.0082 16.3 0.4 0.1 12.8 0.0 2.9 2 0 0 2 2 2 1 Homer-binding domain of metabotropic glutamate receptor DHO_dh PF01180.21 KXH64558.1 - 4.5e-69 232.9 0.5 1.1e-57 195.5 0.0 2.1 2 0 0 2 2 2 2 Dihydroorotate dehydrogenase Mpv17_PMP22 PF04117.12 KXH64558.1 - 5.3e-15 55.4 0.2 1e-14 54.4 0.2 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family PcrB PF01884.17 KXH64558.1 - 0.0092 15.5 0.6 0.42 10.0 0.1 2.3 2 0 0 2 2 2 1 PcrB family FMN_dh PF01070.18 KXH64558.1 - 0.016 14.2 0.5 0.3 10.1 0.3 2.2 2 0 0 2 2 2 0 FMN-dependent dehydrogenase PEP_hydrolase PF09370.10 KXH64558.1 - 0.15 11.3 0.1 5.7 6.1 0.0 2.5 3 0 0 3 3 3 0 Phosphoenolpyruvate hydrolase-like DIT1_PvcA PF05141.12 KXH64559.1 - 3.4e-87 292.4 0.0 5.7e-87 291.7 0.0 1.3 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein MFS_1 PF07690.16 KXH64560.1 - 4.7e-24 85.0 52.4 5.5e-24 84.7 39.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Cu-oxidase_3 PF07732.15 KXH64561.1 - 5.1e-40 136.2 8.9 2e-38 131.0 2.5 3.5 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 KXH64561.1 - 7e-28 97.7 0.0 1.4e-27 96.7 0.0 1.5 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KXH64561.1 - 3.8e-26 91.5 16.0 1.1e-25 89.9 1.9 3.5 3 1 0 3 3 3 2 Multicopper oxidase Acyl-CoA_dh_1 PF00441.24 KXH64562.1 - 6.3e-23 81.6 0.0 1.2e-22 80.8 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KXH64562.1 - 1.8e-14 54.4 0.0 3.8e-14 53.3 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KXH64562.1 - 3.8e-05 24.0 0.1 8e-05 22.9 0.0 1.5 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KXH64562.1 - 0.006 16.8 0.0 0.014 15.5 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Pectate_lyase PF03211.13 KXH64563.1 - 3e-77 258.8 6.5 3.6e-77 258.5 6.5 1.0 1 0 0 1 1 1 1 Pectate lyase Rhodanese PF00581.20 KXH64564.1 - 6.8e-12 45.9 0.0 1.2e-11 45.1 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain Meth_synt_2 PF01717.18 KXH64565.1 - 3.2e-11 43.1 0.0 2.2e-08 33.8 0.0 2.9 2 1 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain MFS_1 PF07690.16 KXH64566.1 - 9.1e-21 74.2 36.1 4.9e-20 71.8 36.1 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KXH64566.1 - 2.8e-09 36.0 5.2 2.8e-09 36.0 5.2 1.8 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) AMP-binding PF00501.28 KXH64567.1 - 5.8e-149 496.3 0.0 1.5e-75 254.4 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.20 KXH64567.1 - 5.3e-41 140.8 0.0 3.8e-35 121.4 0.0 2.7 2 1 0 2 2 2 2 Condensation domain NAD_binding_4 PF07993.12 KXH64567.1 - 7.8e-37 126.8 0.0 1.7e-36 125.7 0.0 1.6 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.25 KXH64567.1 - 6.6e-20 71.2 0.2 3.5e-13 49.7 0.1 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site Epimerase PF01370.21 KXH64567.1 - 2.6e-07 30.4 0.0 8.8e-07 28.6 0.0 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family AMP-binding_C PF13193.6 KXH64567.1 - 1.5e-05 25.9 0.0 0.014 16.4 0.0 2.8 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain NAD_binding_10 PF13460.6 KXH64567.1 - 0.02 14.8 0.5 0.37 10.6 0.2 2.7 2 0 0 2 2 2 0 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KXH64567.1 - 0.066 12.6 0.2 0.39 10.1 0.2 2.0 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase FMN_dh PF01070.18 KXH64568.1 - 4.1e-107 358.2 0.0 4.9e-107 358.0 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 KXH64568.1 - 0.0001 21.6 0.1 0.00015 21.1 0.1 1.1 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 KXH64568.1 - 0.00011 21.4 0.2 0.00018 20.6 0.2 1.2 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.21 KXH64568.1 - 0.0084 15.6 1.9 0.027 14.0 0.3 2.3 2 1 1 3 3 3 1 Histidine biosynthesis protein GMC_oxred_N PF00732.19 KXH64569.1 - 1.1e-78 264.6 0.0 1.6e-78 264.1 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXH64569.1 - 5.6e-34 117.7 0.1 1.1e-33 116.8 0.1 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KXH64569.1 - 0.00033 19.8 0.1 0.00052 19.2 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 KXH64569.1 - 0.00084 18.5 0.0 0.65 9.0 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 KXH64569.1 - 0.01 15.1 0.0 0.018 14.3 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXH64569.1 - 0.015 14.9 0.6 0.091 12.3 0.6 2.2 1 1 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.17 KXH64569.1 - 0.018 14.3 0.0 0.033 13.4 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.27 KXH64569.1 - 0.12 13.0 0.0 0.36 11.4 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 KXH64569.1 - 0.18 12.1 0.0 0.41 10.9 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain MFS_1 PF07690.16 KXH64570.1 - 7.5e-36 123.8 41.3 2.6e-25 89.1 21.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KXH64570.1 - 2.7e-13 49.2 15.6 1e-12 47.3 15.6 1.7 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KXH64570.1 - 3.6e-08 32.7 10.8 3.6e-08 32.7 10.8 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_3 PF05977.13 KXH64570.1 - 0.65 8.3 11.9 0.049 12.0 5.1 2.1 2 0 0 2 2 2 0 Transmembrane secretion effector Pkinase_C PF00433.24 KXH64572.1 - 2.1e-13 50.7 2.8 6.3e-13 49.2 2.2 2.1 2 0 0 2 2 2 1 Protein kinase C terminal domain C2 PF00168.30 KXH64572.1 - 0.031 14.5 0.0 0.052 13.9 0.0 1.3 1 0 0 1 1 1 0 C2 domain Dabb PF07876.12 KXH64595.1 - 6.2e-06 26.8 0.0 1.1e-05 26.0 0.0 1.5 1 1 0 1 1 1 1 Stress responsive A/B Barrel Domain Topo_Zn_Ribbon PF08272.11 KXH64595.1 - 0.15 11.7 0.8 0.51 10.0 0.0 2.2 3 0 0 3 3 3 0 Topoisomerase I zinc-ribbon-like FlxA PF14282.6 KXH64596.1 - 6.4 6.8 13.5 20 5.2 0.2 2.7 2 0 0 2 2 2 0 FlxA-like protein 2OG-FeII_Oxy_3 PF13640.6 KXH64598.1 - 4.7e-09 37.0 0.0 9.3e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Tannase PF07519.11 KXH64601.1 - 3.7e-99 332.7 5.9 4.4e-99 332.5 5.9 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Zn_clus PF00172.18 KXH64603.1 - 3.6e-07 30.2 9.9 3.6e-07 30.2 9.9 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KXH64603.1 - 0.06 12.1 0.1 0.11 11.3 0.0 1.4 2 0 0 2 2 2 0 Fungal specific transcription factor domain TPR_MalT PF17874.1 KXH64603.1 - 0.21 10.9 0.0 0.34 10.2 0.0 1.3 1 0 0 1 1 1 0 MalT-like TPR region Methyltransf_23 PF13489.6 KXH64604.1 - 4.2e-18 65.7 0.0 7.2e-18 65.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH64604.1 - 8.1e-11 42.5 0.0 1.7e-10 41.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH64604.1 - 9.9e-09 35.2 0.0 4.4e-08 33.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH64604.1 - 5.7e-08 33.3 0.0 1.4e-07 32.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH64604.1 - 9.6e-06 26.3 0.0 0.00014 22.5 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KXH64604.1 - 0.00046 19.7 0.0 0.00066 19.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 KXH64604.1 - 0.0062 15.9 0.0 0.044 13.1 0.0 2.0 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.19 KXH64604.1 - 0.017 15.2 0.0 0.029 14.5 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase MTS PF05175.14 KXH64604.1 - 0.041 13.4 0.0 0.13 11.8 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_16 PF10294.9 KXH64604.1 - 0.047 13.4 0.0 0.096 12.4 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase CheR PF01739.18 KXH64604.1 - 0.082 12.4 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain SPR1 PF15356.6 KXH64617.1 - 0.067 13.7 0.7 0.067 13.7 0.7 1.8 2 0 0 2 2 2 0 Psoriasis susceptibility locus 2 RNB PF00773.19 KXH64635.1 - 1.2e-56 192.5 0.0 2.2e-56 191.6 0.0 1.5 1 0 0 1 1 1 1 RNB domain Rhomboid PF01694.22 KXH64636.1 - 8.8e-23 81.0 13.1 8.8e-23 81.0 13.1 2.1 1 1 1 2 2 2 1 Rhomboid family Pex14_N PF04695.13 KXH64636.1 - 8.2 7.1 9.6 1.5 9.5 2.2 3.1 2 1 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PepSY_2 PF13670.6 KXH64638.1 - 0.11 12.6 0.1 8.4 6.5 0.0 2.4 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain DUF2735 PF10931.8 KXH64639.1 - 0.18 12.5 0.2 0.76 10.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2735) IU_nuc_hydro PF01156.19 KXH64641.1 - 3.1e-55 187.9 0.0 5.4e-55 187.1 0.0 1.3 1 1 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase LSM PF01423.22 KXH64642.1 - 7.6e-16 57.6 0.0 9.5e-16 57.3 0.0 1.1 1 0 0 1 1 1 1 LSM domain HECT_2 PF09814.9 KXH64644.1 - 5.3e-97 325.0 0.0 6e-97 324.8 0.0 1.0 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Kelch_6 PF13964.6 KXH64645.1 - 2.5e-06 27.5 2.2 0.28 11.6 0.0 4.7 4 0 0 4 4 4 2 Kelch motif Glycophorin_A PF01102.18 KXH64645.1 - 0.00055 20.1 1.1 0.0016 18.7 1.1 1.8 1 0 0 1 1 1 1 Glycophorin A Podoplanin PF05808.11 KXH64645.1 - 0.0011 19.1 3.6 0.0037 17.4 3.1 2.2 2 0 0 2 2 2 1 Podoplanin RIFIN PF02009.16 KXH64645.1 - 0.0054 16.7 0.0 0.0087 16.0 0.0 1.2 1 0 0 1 1 1 1 Rifin Kelch_3 PF13415.6 KXH64645.1 - 0.014 15.7 0.1 0.014 15.7 0.1 5.6 7 0 0 7 7 7 0 Galactose oxidase, central domain Amnionless PF14828.6 KXH64645.1 - 0.02 13.7 0.1 0.032 13.1 0.1 1.3 1 0 0 1 1 1 0 Amnionless TMEM154 PF15102.6 KXH64645.1 - 0.028 14.3 4.2 0.11 12.4 4.2 2.0 1 1 0 1 1 1 0 TMEM154 protein family CD34_antigen PF06365.12 KXH64645.1 - 0.073 12.6 2.7 0.39 10.3 0.1 2.2 1 1 1 2 2 2 0 CD34/Podocalyxin family Apt1 PF10351.9 KXH64645.1 - 0.13 11.1 1.3 0.2 10.4 1.3 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Mid2 PF04478.12 KXH64645.1 - 0.17 11.7 0.0 0.17 11.7 0.0 2.3 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor Stevor PF17410.2 KXH64645.1 - 0.18 11.3 1.5 0.3 10.6 1.5 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame AJAP1_PANP_C PF15298.6 KXH64645.1 - 0.22 11.7 7.1 0.54 10.4 7.1 1.6 1 0 0 1 1 1 0 AJAP1/PANP C-terminus RAP1 PF07218.11 KXH64645.1 - 9.7 4.3 18.6 13 3.9 18.6 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) TAP_C PF03943.13 KXH64646.1 - 8.3e-19 67.0 0.1 1.4e-18 66.2 0.1 1.4 1 0 0 1 1 1 1 TAP C-terminal domain LRR_4 PF12799.7 KXH64646.1 - 2.1e-09 37.5 5.9 5.3e-06 26.7 0.9 3.0 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXH64646.1 - 4e-06 26.5 0.2 1.2e-05 25.0 0.2 1.9 1 0 0 1 1 1 1 Leucine rich repeat NTF2 PF02136.20 KXH64646.1 - 1.3e-05 25.7 0.0 3.4e-05 24.4 0.0 1.8 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_9 PF18444.1 KXH64646.1 - 2.4e-05 24.1 0.1 8.4e-05 22.3 0.1 1.9 1 1 0 1 1 1 1 RNA recognition motif LRR_9 PF14580.6 KXH64646.1 - 0.00023 20.7 0.1 0.00041 19.9 0.1 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_1 PF00560.33 KXH64646.1 - 0.03 14.8 0.3 13 6.8 0.0 3.5 2 0 0 2 2 2 0 Leucine Rich Repeat LRR_6 PF13516.6 KXH64646.1 - 0.11 12.6 3.3 1.1 9.5 0.2 3.3 3 0 0 3 3 3 0 Leucine Rich repeat ResIII PF04851.15 KXH64647.1 - 3.4e-24 85.8 0.0 8.5e-24 84.5 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KXH64647.1 - 9.6e-22 77.4 0.1 2.2e-21 76.3 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KXH64647.1 - 4.8e-17 62.3 0.2 3.7e-16 59.4 0.0 2.5 4 0 0 4 4 4 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 KXH64647.1 - 1.9e-05 24.4 0.0 4.2e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 SWI2/SNF2 ATPase FANCM-MHF_bd PF16783.5 KXH64647.1 - 0.0048 17.0 0.0 0.0099 15.9 0.0 1.5 1 0 0 1 1 1 1 FANCM to MHF binding domain AAA_22 PF13401.6 KXH64647.1 - 0.011 16.0 0.0 0.05 13.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain TSP_3 PF02412.18 KXH64647.1 - 1.8 8.3 5.7 5.4 6.8 5.7 1.8 1 0 0 1 1 1 0 Thrombospondin type 3 repeat zf-C2H2 PF00096.26 KXH64648.1 - 0.0082 16.6 2.7 0.0082 16.6 2.7 2.7 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 KXH64648.1 - 0.04 13.7 0.4 0.04 13.7 0.4 2.9 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-RanBP PF00641.18 KXH64648.1 - 0.11 11.8 1.1 0.25 10.7 1.1 1.6 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others DUF2956 PF11169.8 KXH64649.1 - 0.36 11.0 0.0 0.36 11.0 0.0 3.1 4 2 0 4 4 4 0 Protein of unknown function (DUF2956) Isy1 PF06246.12 KXH64650.1 - 0.019 14.5 0.9 0.043 13.4 0.9 1.5 1 0 0 1 1 1 0 Isy1-like splicing family CDC45 PF02724.14 KXH64650.1 - 1.4 7.1 3.1 2.9 6.1 3.1 1.4 1 0 0 1 1 1 0 CDC45-like protein CAP59_mtransfer PF11735.8 KXH64651.1 - 1.2e-81 273.9 0.0 1.6e-81 273.6 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 PMT PF02366.18 KXH64653.1 - 1.1e-79 267.4 16.8 3.7e-79 265.8 16.8 1.9 1 1 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 KXH64653.1 - 3.3e-70 235.8 4.6 3.3e-70 235.8 4.6 2.9 2 1 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 KXH64653.1 - 5.3e-21 75.3 0.5 1.5e-20 73.8 0.2 1.7 1 1 1 2 2 2 2 MIR domain RAMP4 PF06624.12 KXH64653.1 - 0.02 14.9 0.4 0.73 9.9 0.2 2.7 2 0 0 2 2 2 0 Ribosome associated membrane protein RAMP4 DUF334 PF03904.13 KXH64653.1 - 1.5 8.3 2.7 0.68 9.4 0.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF334) Ribonuc_L-PSP PF01042.21 KXH64654.1 - 3.5e-41 140.0 0.0 4.3e-41 139.7 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP UCR_UQCRX_QCR9 PF05365.12 KXH64655.1 - 8.2e-20 70.5 1.3 9e-20 70.4 1.3 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Cation_ATPase_C PF00689.21 KXH64656.1 - 6.8e-45 153.0 3.7 6.8e-45 153.0 3.7 2.5 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KXH64656.1 - 5.4e-39 133.6 0.4 5.4e-39 133.6 0.4 2.7 4 0 0 4 4 4 1 E1-E2 ATPase Cation_ATPase PF13246.6 KXH64656.1 - 1.3e-22 79.7 0.0 2.6e-22 78.7 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KXH64656.1 - 1.5e-18 67.8 0.0 3.7e-18 66.6 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KXH64656.1 - 2.4e-07 30.3 0.2 8.7e-07 28.5 0.0 2.1 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KXH64656.1 - 1.2e-05 25.2 0.3 0.00083 19.2 0.2 2.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KXH64656.1 - 0.04 14.3 0.0 0.12 12.8 0.0 1.8 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Viral_Beta_CD PF04530.12 KXH64656.1 - 0.085 13.2 0.0 0.9 9.8 0.0 2.5 2 0 0 2 2 2 0 Viral Beta C/D like family Mago-bind PF09282.10 KXH64657.1 - 1.3e-14 53.7 3.1 2.5e-14 52.8 3.1 1.5 1 0 0 1 1 1 1 Mago binding Nucleo_P87 PF07267.11 KXH64657.1 - 0.083 11.7 3.4 0.084 11.7 3.4 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF4407 PF14362.6 KXH64657.1 - 0.81 9.0 5.8 0.85 8.9 5.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RR_TM4-6 PF06459.12 KXH64657.1 - 0.81 9.5 7.5 0.93 9.3 7.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 NPR3 PF03666.13 KXH64657.1 - 3.3 6.4 5.1 3.8 6.2 5.1 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Presenilin PF01080.17 KXH64657.1 - 5.6 5.6 4.5 6.3 5.4 4.5 1.1 1 0 0 1 1 1 0 Presenilin Sortilin-Vps10 PF15902.5 KXH64658.1 - 8.4e-295 977.3 27.3 2e-152 508.1 12.8 2.1 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 KXH64658.1 - 1.4e-90 302.1 37.0 6.2e-50 169.9 10.8 3.4 3 0 0 3 3 3 2 Sortilin, neurotensin receptor 3, C-terminal BNR PF02012.20 KXH64658.1 - 1.1e-12 45.9 41.8 0.25 11.5 0.1 11.4 10 0 0 10 10 10 7 BNR/Asp-box repeat PSII_BNR PF14870.6 KXH64658.1 - 1.2e-05 24.8 6.5 0.17 11.1 0.0 5.6 4 1 1 5 5 5 2 Photosynthesis system II assembly factor YCF48 CHB_HEX_C PF03174.13 KXH64658.1 - 0.00022 21.1 3.3 0.43 10.6 0.1 4.4 4 0 0 4 4 4 2 Chitobiase/beta-hexosaminidase C-terminal domain DUF2561 PF10812.8 KXH64658.1 - 0.058 13.4 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) preSET_CXC PF18264.1 KXH64658.1 - 1.7 9.2 10.2 4.6 7.8 1.2 2.8 2 0 0 2 2 2 0 CXC domain TPT PF03151.16 KXH64663.1 - 8.8e-35 120.4 16.2 1.1e-34 120.1 16.2 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 KXH64663.1 - 0.00066 19.0 18.6 0.0017 17.7 18.6 1.8 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 KXH64663.1 - 0.024 14.8 34.0 0.35 11.0 14.0 2.5 2 1 0 2 2 2 0 EamA-like transporter family BTP PF05232.12 KXH64663.1 - 0.28 11.3 5.5 15 5.8 0.0 3.5 3 0 0 3 3 3 0 Chlorhexidine efflux transporter DUF2235 PF09994.9 KXH64665.1 - 1.2e-83 280.8 0.0 1.5e-83 280.5 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) SBP_bac_6 PF13343.6 KXH64666.1 - 2.2e-13 50.2 0.1 3.1e-13 49.7 0.1 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 KXH64666.1 - 6.7e-08 32.7 0.2 5.1e-07 29.8 0.1 2.0 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.6 KXH64666.1 - 5.9e-05 22.9 0.1 9.1e-05 22.3 0.1 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 KXH64666.1 - 0.0079 16.2 0.2 0.015 15.3 0.2 1.8 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein RIIa PF02197.17 KXH64666.1 - 0.056 13.1 0.1 0.12 12.1 0.1 1.6 1 0 0 1 1 1 0 Regulatory subunit of type II PKA R-subunit PhrC_PhrF PF11131.8 KXH64667.1 - 0.087 12.4 0.4 0.14 11.7 0.4 1.3 1 0 0 1 1 1 0 Rap-phr extracellular signalling Peptidase_S3 PF00944.19 KXH64667.1 - 0.1 12.4 0.1 0.13 12.1 0.1 1.2 1 0 0 1 1 1 0 Alphavirus core protein GST_N_2 PF13409.6 KXH64668.1 - 0.012 15.9 0.0 0.018 15.3 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KXH64668.1 - 0.13 12.7 0.0 0.24 11.9 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Ank_2 PF12796.7 KXH64669.1 - 5.5e-24 84.6 0.0 1.6e-12 47.8 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KXH64669.1 - 7e-11 42.1 2.4 0.01 16.3 0.0 4.1 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.6 KXH64669.1 - 7.4e-10 39.2 0.1 0.048 14.3 0.0 3.6 2 2 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXH64669.1 - 9.8e-10 37.8 0.3 0.015 15.8 0.0 4.4 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 KXH64669.1 - 3.1e-07 30.5 0.3 6.9e-05 23.1 0.0 3.1 2 1 1 3 3 3 1 Ankyrin repeats (many copies) F-box PF00646.33 KXH64669.1 - 1.7e-06 27.7 0.0 3.4e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KXH64669.1 - 3.1e-05 23.8 0.0 5.2e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 F-box-like PRANC PF09372.10 KXH64669.1 - 0.029 14.7 0.1 0.05 13.9 0.1 1.3 1 0 0 1 1 1 0 PRANC domain Sulfatase PF00884.23 KXH64671.1 - 6.3e-75 252.4 0.0 7.4e-75 252.2 0.0 1.0 1 0 0 1 1 1 1 Sulfatase DUF229 PF02995.17 KXH64671.1 - 0.0027 16.4 0.0 0.0039 15.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Phosphodiest PF01663.22 KXH64671.1 - 0.011 15.3 0.0 2.2 7.8 0.0 2.3 2 0 0 2 2 2 0 Type I phosphodiesterase / nucleotide pyrophosphatase RNA_pol_Rpb1_4 PF05000.17 KXH64671.1 - 0.028 14.4 0.1 0.067 13.1 0.1 1.6 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 4 DUF4976 PF16347.5 KXH64671.1 - 0.045 14.0 0.0 0.16 12.3 0.0 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4976) Sugar_tr PF00083.24 KXH64672.1 - 7.2e-71 239.4 16.2 8.5e-71 239.1 16.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH64672.1 - 3.7e-23 82.0 17.6 3.7e-23 82.0 17.6 1.6 1 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KXH64672.1 - 0.028 12.8 4.8 0.0083 14.6 1.5 1.7 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) ArAE_1 PF06081.11 KXH64672.1 - 6.2 7.0 7.3 10 6.3 0.9 3.0 2 1 1 3 3 3 0 Aromatic acid exporter family member 1 MPLKIP PF15502.6 KXH64673.1 - 0.1 12.8 0.2 0.14 12.4 0.2 1.3 1 0 0 1 1 1 0 M-phase-specific PLK1-interacting protein Sugar_tr PF00083.24 KXH64675.1 - 1.1e-62 212.4 14.4 6.4e-61 206.6 14.4 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH64675.1 - 2.7e-20 72.6 24.8 1.5e-15 57.0 10.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KXH64675.1 - 2.9e-06 26.0 0.7 4.2e-06 25.5 0.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.7 KXH64675.1 - 0.00082 18.3 0.0 0.0048 15.8 0.0 2.2 1 1 0 1 1 1 1 MFS_1 like family p450 PF00067.22 KXH64676.1 - 1.9e-63 214.8 0.0 2.3e-63 214.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 TadE PF07811.12 KXH64676.1 - 0.16 12.3 0.3 0.39 11.0 0.3 1.7 1 0 0 1 1 1 0 TadE-like protein C166 PF17615.2 KXH64678.1 - 2.5e-25 89.5 7.6 3.3e-25 89.1 7.6 1.1 1 0 0 1 1 1 1 Family of unknown function HsbA PF12296.8 KXH64678.1 - 4.5e-05 23.9 0.0 0.00017 22.0 0.0 1.9 1 1 0 1 1 1 1 Hydrophobic surface binding protein A GMC_oxred_N PF00732.19 KXH64679.1 - 2.2e-30 106.1 0.0 8.7e-28 97.5 0.0 2.7 1 1 1 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.13 KXH64679.1 - 8.4e-30 104.2 0.0 1.4e-29 103.5 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 KXH64679.1 - 4e-05 23.0 0.0 0.00013 21.3 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXH64679.1 - 0.00023 20.4 0.3 0.0036 16.4 0.4 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 KXH64679.1 - 0.00032 20.9 0.0 0.00078 19.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KXH64679.1 - 0.0024 17.3 0.0 0.0042 16.5 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KXH64679.1 - 0.015 14.0 0.0 0.026 13.3 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.19 KXH64679.1 - 0.034 13.4 0.2 0.056 12.7 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 KXH64679.1 - 0.045 12.8 0.3 0.097 11.7 0.2 1.5 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox PF00070.27 KXH64679.1 - 0.08 13.5 0.1 0.32 11.6 0.1 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXH64679.1 - 0.14 11.4 0.1 16 4.6 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF4013 PF13197.6 KXH64680.1 - 0.00093 19.1 0.2 0.0015 18.4 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4013) RDD PF06271.12 KXH64680.1 - 0.048 13.9 1.6 0.082 13.1 1.6 1.3 1 0 0 1 1 1 0 RDD family Ank_2 PF12796.7 KXH64681.1 - 2.3e-51 172.3 15.7 1.9e-11 44.4 0.0 8.1 1 1 6 8 8 8 7 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXH64681.1 - 1.7e-35 117.0 13.4 0.016 15.7 0.0 14.1 14 0 0 14 14 14 8 Ankyrin repeat Ank_4 PF13637.6 KXH64681.1 - 2.7e-35 120.3 9.4 7.1e-06 26.5 0.2 10.3 7 3 4 11 11 11 9 Ankyrin repeats (many copies) Ank PF00023.30 KXH64681.1 - 4.7e-24 83.7 28.9 0.001 19.4 0.4 12.5 13 0 0 13 13 12 6 Ankyrin repeat Ank_5 PF13857.6 KXH64681.1 - 7e-24 83.6 22.8 0.00041 20.6 0.2 11.7 7 4 6 13 13 13 8 Ankyrin repeats (many copies) Abhydrolase_6 PF12697.7 KXH64681.1 - 0.00016 22.4 0.0 0.00044 20.9 0.0 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXH64681.1 - 0.00033 20.0 0.0 0.00077 18.8 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF676 PF05057.14 KXH64681.1 - 0.001 18.6 0.0 0.0023 17.5 0.0 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) AAA_16 PF13191.6 KXH64681.1 - 0.0012 19.2 0.5 0.034 14.5 0.0 3.6 3 0 0 3 3 3 1 AAA ATPase domain PGAP1 PF07819.13 KXH64681.1 - 0.0022 17.8 0.0 0.0066 16.2 0.0 1.7 2 0 0 2 2 2 1 PGAP1-like protein Esterase PF00756.20 KXH64681.1 - 0.037 13.7 0.0 0.1 12.2 0.0 1.7 1 0 0 1 1 1 0 Putative esterase Pox_A_type_inc PF04508.12 KXH64681.1 - 0.052 13.4 2.2 0.41 10.6 0.1 3.1 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat AAA_11 PF13086.6 KXH64681.1 - 0.58 9.9 0.0 0.58 9.9 0.0 3.0 2 1 1 3 3 1 0 AAA domain DUF2046 PF09755.9 KXH64681.1 - 1.1 8.4 17.3 2.2 7.5 17.3 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein H4 (DUF2046) SOGA PF11365.8 KXH64681.1 - 1.9 9.7 9.2 0.19 12.9 0.2 3.0 2 0 0 2 2 2 0 Protein SOGA COesterase PF00135.28 KXH64682.1 - 2.5e-91 307.1 0.0 6.1e-91 305.8 0.0 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXH64682.1 - 2.6e-09 37.3 0.0 2.6e-08 34.0 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KXH64682.1 - 0.013 15.0 0.0 0.022 14.2 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family NmrA PF05368.13 KXH64683.1 - 2e-10 40.7 0.0 2.5e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXH64683.1 - 4.6e-10 39.7 0.0 6.8e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KXH64684.1 - 0.038 13.5 0.0 0.052 13.0 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF3176 PF11374.8 KXH64701.1 - 1.3e-34 118.6 1.2 1.3e-34 118.6 1.2 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) DUF3382 PF11862.8 KXH64701.1 - 8.6 6.7 10.8 10 6.5 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3382) Fungal_trans PF04082.18 KXH64703.1 - 4e-12 45.7 0.1 1.3e-11 44.0 0.1 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain Malate_synthase PF01274.22 KXH64704.1 - 4.2e-214 711.7 0.0 4.7e-214 711.5 0.0 1.0 1 0 0 1 1 1 1 Malate synthase HpcH_HpaI PF03328.14 KXH64704.1 - 0.0028 16.8 0.0 0.0057 15.8 0.0 1.5 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family KdgM PF06178.13 KXH64704.1 - 0.13 11.9 0.0 0.21 11.2 0.0 1.2 1 0 0 1 1 1 0 Oligogalacturonate-specific porin protein (KdgM) GMC_oxred_N PF00732.19 KXH64707.1 - 3.4e-46 158.0 0.0 5.1e-46 157.4 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXH64707.1 - 9.4e-25 87.8 0.4 1.7e-24 87.0 0.4 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KXH64707.1 - 0.14 12.4 0.1 0.45 10.8 0.0 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Peptidase_S28 PF05577.12 KXH64708.1 - 3.8e-52 177.6 0.0 2e-51 175.2 0.0 1.8 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Abhydrolase_1 PF00561.20 KXH64709.1 - 2.5e-23 83.1 0.1 1.8e-22 80.2 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXH64709.1 - 3.5e-14 53.9 2.2 7.2e-14 52.9 2.2 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXH64709.1 - 1e-10 41.3 0.0 1.5e-09 37.5 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 KXH64709.1 - 0.076 11.7 0.0 0.12 11.0 0.0 1.2 1 0 0 1 1 1 0 Ndr family TauD PF02668.16 KXH64711.1 - 2.6e-45 155.3 0.3 3.8e-45 154.8 0.3 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family FtsH_ext PF06480.15 KXH64712.1 - 0.89 9.9 2.9 0.63 10.4 1.1 1.7 2 0 0 2 2 2 0 FtsH Extracellular DEAD PF00270.29 KXH64713.1 - 7.7e-42 143.0 0.1 1.3e-41 142.3 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXH64713.1 - 2.7e-33 114.6 0.0 9.7e-33 112.8 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 KXH64713.1 - 0.0005 19.8 0.1 0.00075 19.3 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KXH64713.1 - 0.0014 18.9 0.1 0.012 16.0 0.1 2.2 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 KXH64713.1 - 0.0023 18.0 0.0 0.0045 17.0 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF5393 PF17371.2 KXH64713.1 - 0.053 11.7 0.1 0.084 11.0 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5393) Flavi_DEAD PF07652.14 KXH64713.1 - 0.054 13.5 0.2 0.18 11.8 0.0 2.0 2 1 0 2 2 2 0 Flavivirus DEAD domain TniB PF05621.11 KXH64713.1 - 0.068 12.6 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein Helicase_RecD PF05127.14 KXH64713.1 - 0.081 12.8 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Helicase AAA_22 PF13401.6 KXH64713.1 - 0.17 12.2 1.0 0.82 9.9 1.0 2.0 1 1 0 1 1 1 0 AAA domain DUF3449 PF11931.8 KXH64714.1 - 7.1e-79 263.9 0.4 2.5e-78 262.1 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3449) SF3A3 PF16837.5 KXH64714.1 - 8e-26 90.4 0.5 1.6e-25 89.4 0.5 1.5 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 SF3a60_bindingd PF12108.8 KXH64714.1 - 5e-12 45.5 0.1 1e-11 44.5 0.1 1.6 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-met PF12874.7 KXH64714.1 - 9.1e-09 35.4 1.6 7e-07 29.4 0.7 2.4 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KXH64714.1 - 7.6e-07 29.3 0.8 7.6e-07 29.3 0.8 2.6 2 1 0 2 2 2 1 Zinc-finger double-stranded RNA-binding PRP9_N PF16958.5 KXH64714.1 - 2.9e-05 24.1 4.2 0.041 13.9 0.7 2.9 1 1 1 2 2 2 2 Pre-mRNA-splicing factor PRP9 N-terminus zf-C2H2_2 PF12756.7 KXH64714.1 - 0.0012 19.1 1.5 0.016 15.6 0.6 2.6 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 KXH64714.1 - 0.017 15.9 1.0 2.6 9.1 0.1 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-U1 PF06220.12 KXH64714.1 - 0.13 12.1 0.4 0.38 10.6 0.4 1.8 1 0 0 1 1 1 0 U1 zinc finger zf-C2H2 PF00096.26 KXH64714.1 - 0.51 10.9 4.8 0.88 10.1 0.7 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type Pkinase PF00069.25 KXH64715.1 - 2e-29 102.8 0.0 2.5e-29 102.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXH64715.1 - 2.8e-14 53.0 0.0 5.8e-14 52.0 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXH64715.1 - 0.015 14.1 0.0 0.021 13.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Pox_ser-thr_kin PF05445.11 KXH64715.1 - 0.24 10.3 0.0 0.33 9.9 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase GIY-YIG PF01541.24 KXH64717.1 - 6.2e-12 45.6 0.0 1.1e-11 44.8 0.0 1.4 1 0 0 1 1 1 1 GIY-YIG catalytic domain zf-HC5HC2H PF13771.6 KXH64717.1 - 0.00023 21.4 1.8 0.00042 20.5 1.8 1.3 1 0 0 1 1 1 1 PHD-like zinc-binding domain FANCL_C PF11793.8 KXH64717.1 - 0.00072 19.7 3.0 0.0012 19.0 3.0 1.3 1 0 0 1 1 1 1 FANCL C-terminal domain zf-HC5HC2H_2 PF13832.6 KXH64717.1 - 0.0013 18.9 2.2 0.0022 18.1 2.2 1.3 1 0 0 1 1 1 1 PHD-zinc-finger like domain PHD_Oberon PF07227.11 KXH64717.1 - 0.0086 16.0 1.0 0.014 15.3 1.0 1.2 1 0 0 1 1 1 1 PHD - plant homeodomain finger protein zf-RING-like PF08746.11 KXH64717.1 - 0.096 13.0 6.5 0.22 11.9 6.5 1.7 1 1 0 1 1 1 0 RING-like domain T5orf172 PF10544.9 KXH64717.1 - 0.12 12.9 0.0 0.28 11.7 0.0 1.6 1 0 0 1 1 1 0 T5orf172 domain Prok-RING_1 PF14446.6 KXH64717.1 - 1.8 8.6 9.3 0.14 12.1 2.7 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 PHD PF00628.29 KXH64717.1 - 8.4 6.4 7.5 15 5.6 7.5 1.4 1 0 0 1 1 1 0 PHD-finger PLU-1 PF08429.11 KXH64718.1 - 2.4e-109 365.6 17.2 2.2e-106 355.9 15.7 2.2 2 0 0 2 2 2 2 PLU-1-like protein JmjC PF02373.22 KXH64718.1 - 6.9e-44 148.9 0.2 1.7e-43 147.7 0.2 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase ARID PF01388.21 KXH64718.1 - 2.3e-21 76.2 0.0 7.3e-21 74.6 0.0 2.0 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain PHD PF00628.29 KXH64718.1 - 4.9e-18 64.8 32.3 8.6e-10 38.4 7.7 3.8 3 0 0 3 3 3 2 PHD-finger JmjN PF02375.17 KXH64718.1 - 9e-16 57.5 1.3 2.2e-15 56.3 1.3 1.7 1 0 0 1 1 1 1 jmjN domain zf-C5HC2 PF02928.16 KXH64718.1 - 2e-12 47.3 4.7 2e-12 47.3 4.7 1.9 2 0 0 2 2 1 1 C5HC2 zinc finger zf-HC5HC2H PF13771.6 KXH64718.1 - 0.0055 16.9 18.6 0.029 14.6 1.5 3.5 3 0 0 3 3 3 2 PHD-like zinc-binding domain C1_1 PF00130.22 KXH64718.1 - 0.023 14.6 17.1 0.24 11.3 0.6 3.4 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-HC5HC2H_2 PF13832.6 KXH64718.1 - 0.04 14.1 17.5 0.14 12.4 0.2 3.3 3 0 0 3 3 3 0 PHD-zinc-finger like domain zf-PHD-like PF15446.6 KXH64718.1 - 0.45 10.1 16.2 0.028 14.0 2.0 3.1 3 0 0 3 3 3 0 PHD/FYVE-zinc-finger like domain PHD_2 PF13831.6 KXH64718.1 - 1.9 8.1 12.4 0.081 12.5 1.8 2.9 2 0 0 2 2 2 0 PHD-finger zf-RING_2 PF13639.6 KXH64718.1 - 8.8 6.8 23.0 13 6.2 8.2 3.0 2 0 0 2 2 2 0 Ring finger domain DJ-1_PfpI PF01965.24 KXH64719.1 - 3.7e-14 52.9 0.0 2.1e-13 50.4 0.0 2.1 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 KXH64719.1 - 5.2e-12 45.9 0.1 2.3e-11 43.8 0.0 1.8 1 1 0 1 1 1 1 ThiJ/PfpI family-like GATase_3 PF07685.14 KXH64719.1 - 0.061 12.9 0.0 0.096 12.3 0.0 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain Methyltransf_23 PF13489.6 KXH64720.1 - 2.5e-24 86.0 0.0 3.7e-24 85.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH64720.1 - 4.6e-11 43.3 0.0 1.2e-10 42.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH64720.1 - 4.3e-08 33.1 0.0 5.1e-07 29.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH64720.1 - 5.9e-08 33.4 0.0 3.7e-07 30.8 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH64720.1 - 6.8e-06 26.7 0.0 1.4e-05 25.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KXH64720.1 - 0.0014 18.1 0.0 0.0021 17.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.9 KXH64720.1 - 0.0056 16.4 0.0 0.022 14.5 0.0 1.8 2 0 0 2 2 2 1 Lysine methyltransferase MTS PF05175.14 KXH64720.1 - 0.028 14.0 0.0 0.054 13.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain CMAS PF02353.20 KXH64720.1 - 0.039 13.2 0.0 0.059 12.7 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_4 PF02390.17 KXH64720.1 - 0.043 13.3 0.0 0.12 11.8 0.0 1.7 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_2 PF00891.18 KXH64720.1 - 0.058 12.7 0.0 0.25 10.6 0.0 2.0 2 0 0 2 2 2 0 O-methyltransferase domain FtsJ PF01728.19 KXH64720.1 - 0.087 12.9 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase DUF938 PF06080.12 KXH64720.1 - 0.09 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Aldo_ket_red PF00248.21 KXH64721.1 - 5.2e-66 222.8 0.0 6.1e-66 222.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family TAF6_C PF07571.13 KXH64722.1 - 8.5e-28 96.5 0.0 1.8e-27 95.5 0.0 1.6 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain TAF PF02969.17 KXH64722.1 - 1.3e-21 76.5 0.0 3.5e-21 75.1 0.0 1.8 2 0 0 2 2 2 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 KXH64722.1 - 0.0093 16.2 0.0 0.03 14.6 0.0 1.9 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KXH64722.1 - 0.022 15.1 0.1 0.036 14.4 0.1 1.4 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.13 KXH64722.1 - 0.074 13.1 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 Bromodomain associated Sdh_cyt PF01127.22 KXH64723.1 - 5.8e-15 55.4 5.5 7.5e-15 55.0 5.5 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit MFS_1 PF07690.16 KXH64724.1 - 3.6e-50 170.9 56.8 5.2e-41 140.7 39.4 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KXH64724.1 - 1.6e-19 69.8 22.9 2.1e-19 69.4 22.9 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KXH64724.1 - 5.3e-17 61.8 5.8 5.3e-17 61.8 5.8 3.6 3 1 1 4 4 4 1 Sugar (and other) transporter MerC PF03203.14 KXH64724.1 - 2.4 8.7 0.0 2.4 8.7 0.0 4.8 3 1 2 5 5 5 0 MerC mercury resistance protein PALP PF00291.25 KXH64725.1 - 5e-30 104.9 0.0 8.2e-30 104.2 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Rhodanese PF00581.20 KXH64725.1 - 0.009 16.5 0.0 0.025 15.1 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain Oxidored_FMN PF00724.20 KXH64726.1 - 2.7e-41 142.0 0.0 7.6e-35 120.8 0.0 1.9 2 0 0 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family p450 PF00067.22 KXH64727.1 - 3.3e-69 233.8 0.0 4.4e-69 233.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.20 KXH64727.1 - 4.1e-25 88.7 0.0 7.9e-25 87.7 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KXH64727.1 - 1.7e-21 76.9 0.0 3.3e-21 76.0 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 KXH64727.1 - 7.9e-08 32.9 0.0 1.7e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 KXH64727.1 - 0.00069 19.9 0.0 0.0012 19.1 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin domain Syntaxin PF00804.25 KXH64727.1 - 0.0027 17.4 0.0 0.0047 16.6 0.0 1.3 1 0 0 1 1 1 1 Syntaxin FAD_binding_6 PF00970.24 KXH64727.1 - 0.19 12.1 0.0 0.55 10.6 0.0 1.7 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain Aminotran_1_2 PF00155.21 KXH64728.1 - 1.8e-22 80.0 0.0 1.4e-08 34.3 0.0 3.4 3 0 0 3 3 3 3 Aminotransferase class I and II OKR_DC_1 PF01276.20 KXH64728.1 - 0.0013 17.6 0.0 0.0019 17.0 0.0 1.2 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain Beta_elim_lyase PF01212.21 KXH64728.1 - 0.099 11.9 0.2 1.6 7.9 0.0 2.5 3 0 0 3 3 3 0 Beta-eliminating lyase TIP120 PF08623.10 KXH64728.1 - 0.13 12.0 0.0 0.41 10.4 0.0 1.8 1 0 0 1 1 1 0 TATA-binding protein interacting (TIP20) hNIFK_binding PF12196.8 KXH64728.1 - 0.15 11.6 0.1 0.3 10.6 0.1 1.5 1 0 0 1 1 1 0 FHA Ki67 binding domain of hNIFK GRP PF07172.11 KXH64729.1 - 0.00049 20.7 11.5 0.00049 20.7 11.5 1.8 2 1 0 2 2 2 1 Glycine rich protein family DUF4407 PF14362.6 KXH64729.1 - 0.0067 15.8 0.3 0.0067 15.8 0.3 1.8 1 1 1 2 2 2 1 Domain of unknown function (DUF4407) RhlB PF12300.8 KXH64729.1 - 1.2 9.3 8.3 1.6 8.9 3.6 2.0 1 1 1 2 2 2 0 ATP-dependent RNA helicase RhlB CsbD PF05532.12 KXH64731.1 - 2e-07 30.8 9.8 0.00024 21.0 1.6 2.2 1 1 1 2 2 2 2 CsbD-like Sugar_tr PF00083.24 KXH64732.1 - 6.9e-96 321.9 17.3 8.1e-96 321.6 17.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH64732.1 - 1.4e-23 83.4 26.1 1.4e-23 83.4 26.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KXH64732.1 - 0.00017 20.2 3.5 0.00026 19.6 0.4 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Phage_holin_3_2 PF04550.12 KXH64732.1 - 0.43 11.2 4.2 0.34 11.5 0.9 2.5 2 0 0 2 2 2 0 Phage holin family 2 HET PF06985.11 KXH64733.1 - 5.7e-22 78.6 0.1 8.9e-22 78.0 0.1 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) FAD_binding_3 PF01494.19 KXH64734.1 - 7.2e-27 94.5 0.0 1.2e-25 90.5 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KXH64734.1 - 3.7e-06 26.4 0.5 0.00056 19.2 0.3 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXH64734.1 - 2.1e-05 23.9 0.3 0.0048 16.2 0.7 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KXH64734.1 - 4.7e-05 22.4 3.5 0.032 13.1 0.5 3.0 2 1 1 3 3 3 2 Tryptophan halogenase SE PF08491.10 KXH64734.1 - 5.4e-05 22.4 0.0 0.0015 17.6 0.0 2.1 2 0 0 2 2 2 1 Squalene epoxidase HI0933_like PF03486.14 KXH64734.1 - 9.4e-05 21.3 0.0 0.0022 16.7 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.24 KXH64734.1 - 0.00018 21.2 0.3 0.03 13.9 0.3 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXH64734.1 - 0.0022 18.2 0.1 0.0045 17.2 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KXH64734.1 - 0.0069 15.5 0.1 0.54 9.3 0.1 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein GIDA PF01134.22 KXH64734.1 - 0.017 14.2 0.2 0.023 13.8 0.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_binding_2 PF00890.24 KXH64734.1 - 0.035 13.2 0.9 0.065 12.3 0.8 1.5 1 1 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.7 KXH64734.1 - 0.059 12.7 0.1 0.077 12.3 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.17 KXH64734.1 - 0.19 10.9 0.2 0.38 9.9 0.2 1.4 1 0 0 1 1 1 0 Thi4 family F_bP_aldolase PF01116.20 KXH64735.1 - 5.9e-86 288.4 0.1 6.6e-86 288.3 0.1 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II NAD_binding_11 PF14833.6 KXH64736.1 - 2.5e-40 137.5 0.1 3.3e-26 91.9 0.0 2.6 2 1 0 2 2 2 2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.15 KXH64736.1 - 4.1e-33 114.8 0.5 7.1e-33 114.0 0.5 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KXH64736.1 - 0.0001 22.8 0.5 0.0015 19.0 0.1 2.8 2 1 1 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 KXH64736.1 - 0.015 15.2 0.2 0.039 13.8 0.2 1.7 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 KXH64736.1 - 0.028 13.8 0.0 0.048 13.0 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain YL1 PF05764.13 KXH64737.1 - 0.00049 20.3 0.8 0.00049 20.3 0.8 1.1 1 0 0 1 1 1 1 YL1 nuclear protein PGA2 PF07543.12 KXH64737.1 - 0.0032 17.5 0.9 0.004 17.1 0.9 1.1 1 0 0 1 1 1 1 Protein trafficking PGA2 GAGA_bind PF06217.12 KXH64737.1 - 0.021 15.1 1.4 0.025 14.9 1.4 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family ETRAMP PF09716.10 KXH64737.1 - 0.029 14.4 0.1 0.041 14.0 0.1 1.2 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) MecA PF05389.12 KXH64737.1 - 0.03 13.9 0.7 0.041 13.5 0.7 1.1 1 0 0 1 1 1 0 Negative regulator of genetic competence (MecA) SR-25 PF10500.9 KXH64737.1 - 0.09 12.4 6.5 0.12 12.0 6.5 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Peptidase_C37 PF05416.12 KXH64737.1 - 0.14 10.7 1.6 0.16 10.5 1.6 1.1 1 0 0 1 1 1 0 Southampton virus-type processing peptidase PBP1_TM PF14812.6 KXH64737.1 - 0.18 12.2 4.8 0.3 11.5 4.8 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal LCD1 PF09798.9 KXH64737.1 - 0.23 9.9 0.1 0.28 9.7 0.1 1.0 1 0 0 1 1 1 0 DNA damage checkpoint protein ECM1 PF05782.11 KXH64737.1 - 0.53 9.2 7.6 0.58 9.0 7.6 1.1 1 0 0 1 1 1 0 Extracellular matrix protein 1 (ECM1) Epimerase PF01370.21 KXH64738.1 - 6.6e-05 22.5 0.0 0.00022 20.7 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Peptidase_C24 PF03510.14 KXH64739.1 - 0.12 12.8 0.0 0.13 12.8 0.0 1.1 1 0 0 1 1 1 0 2C endopeptidase (C24) cysteine protease family Acetyltransf_1 PF00583.25 KXH64740.1 - 2e-11 44.2 0.0 4.7e-11 42.9 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXH64740.1 - 8.7e-10 38.6 0.0 5.5e-09 36.0 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXH64740.1 - 1.3e-09 38.4 0.1 1e-08 35.5 0.1 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KXH64740.1 - 6.9e-06 26.2 0.0 4.5e-05 23.5 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXH64740.1 - 2e-05 24.5 0.0 4.5e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 KXH64740.1 - 0.02 15.0 0.0 0.12 12.5 0.0 2.2 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase DUF3669 PF12417.8 KXH64741.1 - 2.4e-22 78.9 0.1 5.1e-22 77.9 0.1 1.6 1 0 0 1 1 1 1 Zinc finger protein TRI12 PF06609.13 KXH64742.1 - 6.8e-50 170.1 24.1 9e-50 169.7 24.1 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 KXH64742.1 - 3e-25 88.9 58.2 3.5e-23 82.1 57.9 3.0 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH64742.1 - 4.5e-08 32.4 15.1 4.5e-08 32.4 15.1 3.5 4 0 0 4 4 4 1 Sugar (and other) transporter DUF4516 PF14990.6 KXH64742.1 - 2.7 7.8 4.9 7.5 6.4 0.5 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4516) SKG6 PF08693.10 KXH64743.1 - 1e-07 31.2 0.2 1.9e-07 30.4 0.2 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain VSP PF03302.13 KXH64743.1 - 0.0059 15.5 6.0 0.0092 14.9 6.0 1.2 1 0 0 1 1 1 1 Giardia variant-specific surface protein DUF4448 PF14610.6 KXH64743.1 - 0.0059 16.4 0.0 0.01 15.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Rax2 PF12768.7 KXH64743.1 - 0.0083 15.6 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 Cortical protein marker for cell polarity SdrD_B PF17210.3 KXH64743.1 - 0.0087 16.3 0.5 0.022 15.0 0.1 1.9 1 1 0 1 1 1 1 SdrD B-like domain Botulinum_HA-17 PF05588.11 KXH64743.1 - 0.072 13.2 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 Clostridium botulinum HA-17 domain GDE_C PF06202.14 KXH64745.1 - 1.2e-05 24.5 0.5 2.2e-05 23.6 0.5 1.3 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase Glyco_hydro_63 PF03200.16 KXH64745.1 - 0.0025 16.6 3.3 0.028 13.2 3.3 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 63 C-terminal domain Ank_2 PF12796.7 KXH64748.1 - 3.6e-46 155.6 4.6 1.5e-15 57.6 0.3 6.4 3 2 2 6 6 6 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXH64748.1 - 4.3e-42 142.0 5.0 3.9e-09 36.9 0.0 8.5 4 2 3 8 8 8 6 Ankyrin repeats (many copies) Ank PF00023.30 KXH64748.1 - 3.1e-37 125.4 0.9 3.1e-07 30.5 0.0 10.1 10 0 0 10 10 10 7 Ankyrin repeat Ank_3 PF13606.6 KXH64748.1 - 1.1e-34 114.5 7.3 0.00052 20.3 0.0 10.6 11 0 0 11 11 11 7 Ankyrin repeat Ank_5 PF13857.6 KXH64748.1 - 3.8e-21 74.9 4.3 0.00065 19.9 0.1 7.6 4 2 2 7 7 7 5 Ankyrin repeats (many copies) PNP_UDP_1 PF01048.20 KXH64748.1 - 3.8e-11 42.7 0.2 7.4e-11 41.7 0.2 1.5 1 0 0 1 1 1 1 Phosphorylase superfamily NACHT PF05729.12 KXH64748.1 - 0.00029 20.8 0.0 0.00082 19.3 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KXH64748.1 - 0.0027 18.1 0.1 0.13 12.7 0.0 3.2 3 0 0 3 3 3 1 AAA ATPase domain AAA_7 PF12775.7 KXH64748.1 - 0.072 12.6 0.0 0.21 11.1 0.0 1.8 1 0 0 1 1 1 0 P-loop containing dynein motor region Rad17 PF03215.15 KXH64748.1 - 0.16 11.9 0.0 0.3 11.0 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain LapA_dom PF06305.11 KXH64749.1 - 0.059 13.2 0.1 0.12 12.2 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain DUF1308 PF07000.11 KXH64750.1 - 5e-07 29.8 0.0 3.7e-06 27.0 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1308) DUF5614 PF18474.1 KXH64750.1 - 0.013 14.8 0.0 0.028 13.7 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5614) DUF1688 PF07958.11 KXH64751.1 - 1.9e-182 606.7 0.0 2.2e-182 606.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) 60KD_IMP PF02096.20 KXH64753.1 - 7.6e-21 74.7 0.5 1.2e-20 74.1 0.5 1.3 1 0 0 1 1 1 1 60Kd inner membrane protein HemY_N PF07219.13 KXH64753.1 - 2.5 8.3 7.0 14 5.9 0.3 2.5 2 0 0 2 2 2 0 HemY protein N-terminus TOM13 PF08219.11 KXH64754.1 - 5.9e-37 125.5 0.0 7.7e-37 125.1 0.0 1.1 1 0 0 1 1 1 1 Outer membrane protein TOM13 SEP PF08059.13 KXH64755.1 - 2.4e-23 82.5 0.0 4.8e-23 81.5 0.0 1.5 1 0 0 1 1 1 1 SEP domain UBX PF00789.20 KXH64755.1 - 1.4e-10 41.2 0.0 2.2e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.6 KXH64755.1 - 2.2e-10 40.2 0.0 4e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 UBA-like domain TAP_C PF03943.13 KXH64755.1 - 0.0014 18.3 0.0 0.0022 17.6 0.0 1.3 1 0 0 1 1 1 1 TAP C-terminal domain Gtr1_RagA PF04670.12 KXH64756.1 - 2.8e-93 311.5 0.0 3.8e-93 311.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.22 KXH64756.1 - 1e-07 31.7 0.0 2.1e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXH64756.1 - 1.2e-07 31.9 0.0 2.3e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KXH64756.1 - 2.4e-07 30.8 0.0 4.1e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 KXH64756.1 - 2.4e-06 27.1 0.0 3.7e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 KXH64756.1 - 0.0027 16.9 3.6 1.1 8.4 0.6 2.9 2 1 1 3 3 3 2 G-protein alpha subunit ABC_tran PF00005.27 KXH64756.1 - 0.0034 17.9 0.1 0.016 15.7 0.0 2.0 2 1 0 2 2 2 1 ABC transporter AAA_29 PF13555.6 KXH64756.1 - 0.0038 16.9 0.9 0.054 13.2 0.2 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KXH64756.1 - 0.015 15.2 0.3 0.27 11.1 0.1 2.2 2 0 0 2 2 2 0 RsgA GTPase DUF815 PF05673.13 KXH64756.1 - 0.019 14.1 0.0 0.044 13.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 KXH64756.1 - 0.034 13.7 0.0 0.44 10.0 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region SRPRB PF09439.10 KXH64756.1 - 0.19 11.1 0.0 0.34 10.3 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit zf-C2H2_4 PF13894.6 KXH64758.1 - 0.05 14.4 5.8 0.2 12.6 0.1 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KXH64758.1 - 0.55 10.8 3.3 0.59 10.7 0.8 2.4 2 0 0 2 2 2 0 Zinc-finger double domain DUF1295 PF06966.12 KXH64759.1 - 1e-31 110.3 0.1 1.5e-31 109.7 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.14 KXH64759.1 - 0.00047 20.5 0.0 0.001 19.4 0.0 1.5 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Steroid_dh PF02544.16 KXH64759.1 - 0.0012 18.8 0.0 0.0023 17.9 0.0 1.3 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase Aspzincin_M35 PF14521.6 KXH64759.1 - 0.015 15.9 0.1 1.3e+02 3.1 0.0 5.1 4 2 2 6 6 6 0 Lysine-specific metallo-endopeptidase DUF2062 PF09835.9 KXH64759.1 - 0.055 13.3 1.0 1.1 9.1 0.6 2.4 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2062) PEMT PF04191.13 KXH64759.1 - 0.14 12.6 0.0 0.29 11.5 0.0 1.5 1 0 0 1 1 1 0 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 KXH64759.1 - 0.22 10.3 0.0 0.35 9.6 0.0 1.2 1 0 0 1 1 1 0 Ergosterol biosynthesis ERG4/ERG24 family MT0933_antitox PF14013.6 KXH64759.1 - 8.5 6.8 9.5 30 5.0 0.4 3.9 3 1 1 4 4 4 0 MT0933-like antitoxin protein AA_permease_2 PF13520.6 KXH64761.1 - 6.5e-59 199.9 46.6 7.5e-59 199.6 46.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXH64761.1 - 6.2e-24 84.4 37.9 8.1e-24 84.0 37.9 1.0 1 0 0 1 1 1 1 Amino acid permease Glucosamine_iso PF01182.20 KXH64762.1 - 1e-24 87.7 0.0 1.4e-24 87.3 0.0 1.2 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase FAD_binding_8 PF08022.12 KXH64762.1 - 0.038 14.1 0.0 0.074 13.1 0.0 1.4 1 0 0 1 1 1 0 FAD-binding domain Hexokinase_2 PF03727.16 KXH64764.1 - 4.9e-68 229.1 0.0 3.1e-51 174.1 0.0 2.2 2 0 0 2 2 2 2 Hexokinase Hexokinase_1 PF00349.21 KXH64764.1 - 7.5e-66 221.8 0.0 1.1e-65 221.3 0.0 1.2 1 0 0 1 1 1 1 Hexokinase HMGL-like PF00682.19 KXH64764.1 - 0.029 13.9 0.0 0.055 13.0 0.0 1.4 1 0 0 1 1 1 0 HMGL-like Alginate_lyase PF05426.12 KXH64765.1 - 6.8e-06 25.8 3.4 2.3e-05 24.1 3.4 1.8 1 1 0 1 1 1 1 Alginate lyase Alginate_lyase PF05426.12 KXH64766.1 - 1.7e-10 40.9 4.7 2.8e-10 40.2 4.7 1.3 1 0 0 1 1 1 1 Alginate lyase Amino_oxidase PF01593.24 KXH64767.1 - 1.7e-37 129.8 0.0 2.2e-37 129.4 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KXH64767.1 - 6.5e-09 35.9 0.0 2.7e-08 33.9 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXH64767.1 - 6.8e-06 25.5 0.0 0.0041 16.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXH64767.1 - 0.0022 18.5 0.5 0.012 16.2 0.1 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXH64767.1 - 0.026 14.1 3.7 0.31 10.6 3.7 2.4 1 1 0 1 1 1 0 FAD dependent oxidoreductase Amidase PF01425.21 KXH64768.1 - 2.7e-26 92.6 0.1 5.8e-26 91.5 0.0 1.6 2 0 0 2 2 2 1 Amidase Myb_Cef PF11831.8 KXH64770.1 - 5.5e-52 176.7 8.7 5.5e-52 176.7 8.7 2.9 3 1 1 4 4 4 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.31 KXH64770.1 - 2.9e-23 81.8 5.3 8.5e-11 41.9 0.9 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KXH64770.1 - 5e-22 77.9 6.8 6.3e-15 55.2 2.8 3.1 2 1 1 3 3 3 2 Myb-like DNA-binding domain Rap1_C PF11626.8 KXH64770.1 - 0.22 11.6 0.1 0.22 11.6 0.1 3.5 4 0 0 4 4 4 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain MFS_1 PF07690.16 KXH64771.1 - 6e-43 147.1 83.6 1.7e-40 139.0 52.9 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH64771.1 - 4.1e-12 45.7 12.6 4.1e-12 45.7 12.6 2.9 2 1 1 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 KXH64771.1 - 2.8e-09 36.0 16.5 4.1e-09 35.4 16.5 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 KXH64771.1 - 0.0033 15.8 1.1 0.0033 15.8 1.1 1.9 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family F-box-like PF12937.7 KXH64772.1 - 0.041 13.8 0.0 0.2 11.5 0.0 2.2 1 1 0 1 1 1 0 F-box-like Mito_carr PF00153.27 KXH64773.1 - 7.4e-16 57.9 0.0 1.3e-09 37.8 0.0 3.0 3 0 0 3 3 3 2 Mitochondrial carrier protein Lactamase_B PF00753.27 KXH64773.1 - 0.0017 18.4 0.2 0.0041 17.2 0.2 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Abhydrolase_4 PF08386.10 KXH64774.1 - 2.5e-22 78.9 0.0 1.9e-21 76.1 0.0 2.1 2 0 0 2 2 2 1 TAP-like protein Abhydrolase_1 PF00561.20 KXH64774.1 - 6e-21 75.3 0.0 2.6e-20 73.2 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold FSH1 PF03959.13 KXH64774.1 - 0.013 15.2 0.0 0.025 14.3 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Orbi_VP7 PF00897.17 KXH64774.1 - 0.054 12.5 0.0 0.079 11.9 0.0 1.2 1 0 0 1 1 1 0 Orbivirus inner capsid protein VP7 T5orf172 PF10544.9 KXH64775.1 - 2.1e-14 53.9 0.1 4.5e-14 52.8 0.1 1.5 1 0 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 KXH64775.1 - 1.8e-06 28.5 0.1 3.8e-06 27.5 0.1 1.6 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 FMO-like PF00743.19 KXH64776.1 - 3.7e-27 95.0 0.0 5e-18 64.8 0.0 2.8 3 0 0 3 3 3 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KXH64776.1 - 6.1e-08 32.3 0.0 1.7e-06 27.5 0.0 2.3 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXH64776.1 - 0.00068 18.9 0.0 0.88 8.7 0.0 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXH64776.1 - 0.0011 18.2 0.0 0.039 13.1 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) CMD PF02627.20 KXH64777.1 - 2.2e-18 66.1 0.1 3.7e-18 65.4 0.1 1.4 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family TraC PF07820.12 KXH64777.1 - 0.075 13.4 0.3 0.76 10.2 0.1 2.3 2 0 0 2 2 2 0 TraC-like protein PAF-AH_p_II PF03403.13 KXH64779.1 - 1.4e-13 50.2 0.0 7.2e-07 28.1 0.0 2.6 1 1 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 KXH64779.1 - 9.8e-08 31.2 0.0 2.6e-07 29.8 0.0 1.6 2 0 0 2 2 2 1 Chlorophyllase enzyme Abhydrolase_6 PF12697.7 KXH64779.1 - 5.3e-06 27.2 0.5 9e-06 26.4 0.5 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXH64779.1 - 7.2e-06 25.4 0.1 8.2e-05 22.0 0.1 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 KXH64779.1 - 0.00018 21.4 0.0 0.00027 20.8 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Chlorophyllase PF07224.11 KXH64779.1 - 0.0027 16.8 0.0 0.011 14.8 0.0 1.9 1 1 0 1 1 1 1 Chlorophyllase Abhydrolase_1 PF00561.20 KXH64779.1 - 0.019 14.6 0.6 0.16 11.6 0.6 2.0 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 KXH64779.1 - 0.039 13.7 0.1 2 8.2 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KXH64779.1 - 0.087 12.3 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family NAD_binding_2 PF03446.15 KXH64780.1 - 7.5e-14 52.2 1.0 7.7e-14 52.2 0.1 1.5 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KXH64780.1 - 9.5e-07 29.3 0.1 2.3e-06 28.1 0.1 1.7 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 KXH64780.1 - 3.3e-06 26.6 0.1 5.9e-06 25.8 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 KXH64780.1 - 0.00044 20.3 3.2 0.019 15.0 3.2 2.2 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Shikimate_DH PF01488.20 KXH64780.1 - 0.00052 20.1 0.2 0.00076 19.6 0.2 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 KXH64780.1 - 0.055 13.4 0.1 0.091 12.6 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 KXH64780.1 - 0.1 12.3 0.1 0.23 11.1 0.1 1.6 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.14 KXH64780.1 - 0.13 11.8 1.1 3.5 7.2 0.6 2.5 1 1 1 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain zf-C2H2 PF00096.26 KXH64781.1 - 0.033 14.6 10.8 0.69 10.5 0.1 3.6 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXH64781.1 - 0.037 14.9 13.0 2.9 9.0 0.4 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger Ank_2 PF12796.7 KXH64782.1 - 2.1e-26 92.3 0.0 1.4e-09 38.4 0.0 3.6 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXH64782.1 - 2.5e-19 69.4 0.0 6.8e-08 32.9 0.0 3.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXH64782.1 - 1.2e-17 62.2 0.1 0.0045 17.4 0.0 6.1 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 KXH64782.1 - 3e-13 49.7 0.0 0.00011 22.4 0.0 4.7 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 KXH64782.1 - 5.8e-10 39.2 0.2 0.09 13.3 0.0 5.5 7 0 0 7 7 7 2 Ankyrin repeat YicC_N PF03755.13 KXH64782.1 - 0.13 12.7 0.8 0.45 11.0 0.1 2.3 2 1 0 2 2 2 0 YicC-like family, N-terminal region Rib_5-P_isom_A PF06026.14 KXH64783.1 - 2e-21 76.4 0.0 2.5e-21 76.1 0.0 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) Ank_2 PF12796.7 KXH64800.1 - 4.5e-14 52.8 0.2 1.2e-05 25.8 0.4 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXH64800.1 - 2.7e-13 50.1 0.3 1.8e-05 25.2 0.0 3.4 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 KXH64800.1 - 1.8e-11 43.9 0.0 0.0013 19.1 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 KXH64800.1 - 9.5e-11 41.7 0.2 5.3e-05 23.4 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXH64800.1 - 9.4e-10 37.9 0.0 0.068 13.8 0.0 4.6 4 0 0 4 4 4 2 Ankyrin repeat KilA-N PF04383.13 KXH64800.1 - 7.7e-08 32.2 0.2 7.5e-07 29.0 0.2 2.4 1 1 0 1 1 1 1 KilA-N domain Aldo_ket_red PF00248.21 KXH64801.1 - 2.5e-52 177.9 0.0 2.9e-52 177.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family EamA PF00892.20 KXH64802.1 - 1.2e-10 41.7 27.9 7.7e-06 26.1 3.7 3.0 2 1 1 3 3 3 2 EamA-like transporter family CSG2 PF16965.5 KXH64802.1 - 0.0017 17.4 20.4 0.0037 16.3 5.9 3.4 2 1 1 3 3 3 2 Ceramide synthase regulator Nuc_sug_transp PF04142.15 KXH64802.1 - 0.0032 16.7 3.6 0.014 14.5 3.6 1.9 1 1 0 1 1 1 1 Nucleotide-sugar transporter SLC35F PF06027.12 KXH64802.1 - 0.0069 15.9 2.4 0.0069 15.9 2.4 2.0 2 0 0 2 2 2 1 Solute carrier family 35 DUF5453 PF17534.2 KXH64802.1 - 0.13 12.3 0.2 0.3 11.0 0.2 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5453) DUF2723 PF11028.8 KXH64802.1 - 0.32 10.9 10.5 0.54 10.2 4.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2723) DUF202 PF02656.15 KXH64802.1 - 0.33 11.4 14.2 0.18 12.3 1.2 4.5 4 1 0 4 4 4 0 Domain of unknown function (DUF202) DUF2070 PF09843.9 KXH64802.1 - 6.6 4.9 10.4 0.88 7.8 2.9 2.1 1 1 0 2 2 2 0 Predicted membrane protein (DUF2070) zf_CCCH_4 PF18345.1 KXH64807.1 - 0.14 12.3 0.2 0.14 12.3 0.2 2.2 2 0 0 2 2 2 0 Zinc finger domain zf-CCCH_4 PF18044.1 KXH64807.1 - 0.23 11.3 3.1 1.2 9.0 0.5 2.5 2 0 0 2 2 2 0 CCCH-type zinc finger zf-CCCH_2 PF14608.6 KXH64807.1 - 6 7.5 6.1 5.3 7.7 1.8 2.8 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger PP-binding PF00550.25 KXH64808.1 - 3.9e-11 43.1 0.1 5.7e-11 42.6 0.1 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 KXH64808.1 - 2.8e-05 24.3 0.1 3.5e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 Acyl-carrier Baculo_PEP_C PF04513.12 KXH64818.1 - 0.00012 22.1 1.4 0.00012 22.1 1.4 7.2 2 2 4 7 7 6 2 Baculovirus polyhedron envelope protein, PEP, C terminus Spc7 PF08317.11 KXH64818.1 - 0.0055 15.6 0.8 0.0055 15.6 0.8 6.7 1 1 7 8 8 8 2 Spc7 kinetochore protein ATG16 PF08614.11 KXH64818.1 - 0.0083 16.4 1.4 0.0083 16.4 1.4 6.4 3 1 2 5 5 5 1 Autophagy protein 16 (ATG16) Fib_alpha PF08702.10 KXH64818.1 - 0.012 15.8 0.1 0.012 15.8 0.1 6.0 4 1 1 5 5 4 0 Fibrinogen alpha/beta chain family TPR_MLP1_2 PF07926.12 KXH64818.1 - 0.012 15.7 2.2 0.012 15.7 2.2 6.3 4 2 3 7 7 7 0 TPR/MLP1/MLP2-like protein Prefoldin_2 PF01920.20 KXH64818.1 - 0.019 14.9 1.4 0.019 14.9 1.4 7.0 4 1 2 6 6 4 0 Prefoldin subunit BLOC1_2 PF10046.9 KXH64818.1 - 0.021 15.1 0.2 0.021 15.1 0.2 6.4 4 1 3 7 7 6 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 XhlA PF10779.9 KXH64818.1 - 0.025 14.8 1.2 0.025 14.8 1.2 5.6 5 0 0 5 5 5 0 Haemolysin XhlA DUF1664 PF07889.12 KXH64818.1 - 0.025 14.6 0.1 0.025 14.6 0.1 6.6 2 2 4 9 9 9 0 Protein of unknown function (DUF1664) DUF4795 PF16043.5 KXH64818.1 - 0.03 13.9 0.1 0.03 13.9 0.1 4.2 3 1 0 4 4 3 0 Domain of unknown function (DUF4795) GCR PF02155.15 KXH64818.1 - 0.036 13.1 1.6 0.072 12.1 0.3 2.2 2 0 0 2 2 2 0 Glucocorticoid receptor Lebercilin PF15619.6 KXH64818.1 - 0.16 11.7 56.1 1.1 8.9 16.4 4.2 3 1 1 4 4 4 0 Ciliary protein causing Leber congenital amaurosis disease DUF1319 PF07028.11 KXH64818.1 - 0.44 10.8 6.7 0.23 11.7 0.4 3.8 3 1 0 3 3 2 0 Protein of unknown function (DUF1319) Exonuc_VII_S PF02609.16 KXH64818.1 - 0.61 10.2 11.9 2.6 8.2 3.4 4.5 2 2 1 3 3 3 0 Exonuclease VII small subunit ApoO PF09769.9 KXH64818.1 - 1.7 8.6 5.2 15 5.6 0.2 3.7 3 1 1 4 4 4 0 Apolipoprotein O Osmo_CC PF08946.10 KXH64818.1 - 3 8.2 12.4 1.1 9.5 0.6 4.7 3 1 1 4 4 4 0 Osmosensory transporter coiled coil DUF1192 PF06698.11 KXH64818.1 - 6.3 6.9 13.9 8.8 6.5 2.0 4.6 3 1 0 3 3 3 0 Protein of unknown function (DUF1192) GAS PF13851.6 KXH64818.1 - 7.7 5.8 52.3 0.65 9.3 0.4 4.8 2 1 1 4 4 4 0 Growth-arrest specific micro-tubule binding Cast PF10174.9 KXH64821.1 - 0.00095 17.5 9.8 0.00095 17.5 9.8 2.2 1 1 1 2 2 2 1 RIM-binding protein of the cytomatrix active zone Laminin_I PF06008.14 KXH64821.1 - 0.0047 16.7 17.4 0.0067 16.2 9.5 2.3 1 1 1 2 2 2 1 Laminin Domain I HIP1_clath_bdg PF16515.5 KXH64821.1 - 0.012 16.2 24.8 0.02 15.5 6.1 3.6 2 2 1 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 TMF_DNA_bd PF12329.8 KXH64821.1 - 0.024 14.6 2.1 0.024 14.6 2.1 4.2 3 1 1 4 4 4 0 TATA element modulatory factor 1 DNA binding NBP1 PF08537.10 KXH64821.1 - 0.024 14.0 20.4 0.032 13.7 7.7 2.1 2 0 0 2 2 2 0 Fungal Nap binding protein NBP1 hDGE_amylase PF14701.6 KXH64821.1 - 0.034 13.3 8.6 0.011 14.8 4.9 1.7 1 1 1 2 2 2 0 Glycogen debranching enzyme, glucanotransferase domain APG6_N PF17675.1 KXH64821.1 - 0.041 14.4 28.0 0.11 13.1 14.7 2.9 1 1 2 3 3 3 0 Apg6 coiled-coil region DUF4407 PF14362.6 KXH64821.1 - 0.047 13.0 17.2 0.71 9.2 17.2 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Fib_alpha PF08702.10 KXH64821.1 - 0.052 13.7 15.9 0.27 11.4 3.1 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family FliJ PF02050.16 KXH64821.1 - 0.053 13.7 16.5 0.15 12.3 6.0 3.1 2 2 1 3 3 3 0 Flagellar FliJ protein Filament PF00038.21 KXH64821.1 - 0.059 12.9 25.2 0.78 9.3 25.2 2.4 1 1 0 1 1 1 0 Intermediate filament protein Cnn_1N PF07989.11 KXH64821.1 - 0.1 12.8 24.5 0.27 11.4 1.3 4.7 2 2 2 4 4 4 0 Centrosomin N-terminal motif 1 Golgin_A5 PF09787.9 KXH64821.1 - 0.18 11.3 20.9 0.17 11.3 17.8 2.0 1 1 0 1 1 1 0 Golgin subfamily A member 5 Spc7 PF08317.11 KXH64821.1 - 0.2 10.5 24.5 1.5 7.7 4.8 2.5 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF745 PF05335.13 KXH64821.1 - 0.32 10.7 12.7 1.4 8.6 3.7 2.8 1 1 3 4 4 4 0 Protein of unknown function (DUF745) GAS PF13851.6 KXH64821.1 - 0.45 9.8 27.8 2.4 7.5 16.7 2.8 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Fez1 PF06818.15 KXH64821.1 - 0.49 10.8 26.5 2.3 8.6 5.1 3.1 1 1 1 3 3 3 0 Fez1 Baculo_PEP_C PF04513.12 KXH64821.1 - 0.64 10.1 9.3 0.46 10.5 3.2 2.8 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus TPR_MLP1_2 PF07926.12 KXH64821.1 - 0.68 10.0 27.6 0.21 11.7 2.8 3.7 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein KxDL PF10241.9 KXH64821.1 - 0.72 10.2 14.7 4.7 7.6 0.1 4.2 3 1 1 4 4 4 0 Uncharacterized conserved protein DUF489 PF04356.12 KXH64821.1 - 1.1 9.2 5.8 3 7.8 2.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF489) CortBP2 PF09727.9 KXH64821.1 - 1.2 9.0 23.7 0.61 10.0 14.2 3.1 1 1 1 2 2 2 0 Cortactin-binding protein-2 Laminin_II PF06009.12 KXH64821.1 - 1.6 8.7 17.9 0.64 10.0 1.1 3.2 1 1 2 3 3 3 0 Laminin Domain II LPP PF04728.13 KXH64821.1 - 2.1 8.8 11.0 1.6 9.2 0.7 3.8 4 0 0 4 4 4 0 Lipoprotein leucine-zipper Prominin PF05478.11 KXH64821.1 - 2.2 6.1 14.4 8.3 4.2 14.6 1.6 1 1 0 1 1 1 0 Prominin T6PP_N PF18572.1 KXH64821.1 - 2.3 8.1 12.9 0.052 13.4 2.6 2.8 1 1 2 3 3 3 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain CENP-H PF05837.12 KXH64821.1 - 2.8 8.4 24.6 0.82 10.1 5.5 3.2 1 1 2 3 3 3 0 Centromere protein H (CENP-H) Prefoldin_2 PF01920.20 KXH64821.1 - 3.3 7.7 22.4 1.4 8.9 1.2 4.0 4 0 0 4 4 4 0 Prefoldin subunit CENP-F_leu_zip PF10473.9 KXH64821.1 - 5.3 7.1 28.8 0.5 10.4 4.1 3.1 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 BRE1 PF08647.11 KXH64821.1 - 7.7 6.7 23.7 2.3 8.4 3.1 3.8 2 2 0 3 3 3 0 BRE1 E3 ubiquitin ligase Spectrin PF00435.21 KXH64821.1 - 9.4 6.8 19.9 5.7 7.5 3.5 3.2 2 1 1 3 3 3 0 Spectrin repeat Tom22 PF04281.13 KXH64822.1 - 2.8e-43 147.0 0.0 3.3e-43 146.8 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 DUF572 PF04502.13 KXH64824.1 - 0.00086 19.0 2.2 0.0014 18.4 2.2 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF572) DUF2461 PF09365.10 KXH64824.1 - 0.012 15.6 4.7 0.033 14.1 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical protein (DUF2461) Rrn6 PF10214.9 KXH64824.1 - 0.056 11.9 7.1 0.09 11.3 7.1 1.3 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Fungal_trans PF04082.18 KXH64838.1 - 6.6e-12 45.0 0.7 1.3e-11 44.1 0.7 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.6 KXH64838.1 - 1.5e-06 28.4 7.3 1.9e-05 24.9 1.1 2.9 2 0 0 2 2 2 2 Zinc-finger double domain zf-Di19 PF05605.12 KXH64838.1 - 0.00077 19.7 4.4 0.0016 18.7 4.4 1.5 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 KXH64838.1 - 0.0014 19.3 15.1 0.065 14.1 5.8 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KXH64838.1 - 0.18 12.1 3.1 9 6.7 0.8 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 KXH64838.1 - 0.35 11.4 14.6 0.38 11.3 7.3 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type Actin PF00022.19 KXH64840.1 - 6.3e-16 58.0 0.0 2.1e-14 53.0 0.0 2.7 3 0 0 3 3 3 1 Actin FtsA PF14450.6 KXH64840.1 - 0.065 13.7 0.0 0.14 12.6 0.0 1.8 1 1 0 1 1 1 0 Cell division protein FtsA DUF4969 PF16339.5 KXH64840.1 - 0.23 11.9 0.9 0.48 10.8 0.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4969) Serglycin PF04360.12 KXH64841.1 - 0.044 13.7 0.8 0.06 13.3 0.8 1.2 1 0 0 1 1 1 0 Serglycin AF-4 PF05110.13 KXH64841.1 - 0.052 11.6 0.3 0.059 11.5 0.3 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein TRP_2 PF08344.11 KXH64841.1 - 0.077 13.2 0.2 0.12 12.6 0.2 1.3 1 0 0 1 1 1 0 Transient receptor ion channel II Ysc84 PF04366.12 KXH64842.1 - 5.2e-31 107.1 0.0 9.3e-31 106.2 0.0 1.5 1 0 0 1 1 1 1 Las17-binding protein actin regulator Halogen_Hydrol PF10112.9 KXH64843.1 - 0.11 12.5 0.1 0.14 12.2 0.1 1.0 1 0 0 1 1 1 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Ribonuc_L-PSP PF01042.21 KXH64844.1 - 1e-26 93.3 0.3 1.1e-26 93.2 0.3 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP DUF1320 PF07030.12 KXH64844.1 - 0.029 14.5 0.0 0.045 13.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1320) SAP PF02037.27 KXH64845.1 - 1.6e-07 30.9 0.1 2.8e-07 30.1 0.1 1.4 1 0 0 1 1 1 1 SAP domain zf-RING_2 PF13639.6 KXH64845.1 - 0.00049 20.4 11.2 0.00049 20.4 11.2 2.0 2 0 0 2 2 2 1 Ring finger domain PHD PF00628.29 KXH64845.1 - 0.0085 16.0 11.8 0.018 14.9 11.8 1.6 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.6 KXH64845.1 - 0.031 14.2 8.9 0.031 14.2 8.9 1.7 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 DUF2116 PF09889.9 KXH64845.1 - 0.85 9.6 6.3 1.8 8.6 6.3 1.6 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) zf-RING_5 PF14634.6 KXH64845.1 - 1.1 9.3 15.5 0.4 10.7 11.7 2.1 2 0 0 2 2 2 0 zinc-RING finger domain C1_1 PF00130.22 KXH64845.1 - 7.6 6.5 14.3 0.61 10.0 8.1 2.2 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Ank_2 PF12796.7 KXH64846.1 - 2.4e-42 143.4 0.0 2.5e-14 53.6 0.2 5.7 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXH64846.1 - 2.2e-32 111.0 3.5 5.4e-07 30.0 0.0 7.6 4 3 4 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXH64846.1 - 6.4e-26 87.6 1.9 0.00052 20.3 0.0 11.0 11 0 0 11 11 11 4 Ankyrin repeat Ank_5 PF13857.6 KXH64846.1 - 1.6e-25 88.8 2.2 1.4e-05 25.2 0.0 7.7 4 1 2 7 7 7 5 Ankyrin repeats (many copies) Ank PF00023.30 KXH64846.1 - 4.3e-24 83.8 0.2 0.024 15.1 0.0 9.1 8 0 0 8 8 8 6 Ankyrin repeat CENP-B_dimeris PF09026.10 KXH64846.1 - 0.52 10.7 5.7 1.2 9.6 5.7 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain RNA_pol_3_Rpc31 PF11705.8 KXH64846.1 - 3.5 7.8 9.2 6.5 6.9 9.2 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Sulf_transp PF04143.14 KXH64847.1 - 1.4e-31 110.3 27.2 2e-31 109.7 26.6 1.6 1 1 0 1 1 1 1 Sulphur transport Lactamase_B PF00753.27 KXH64848.1 - 2.6e-17 63.5 0.6 4e-17 62.9 0.6 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KXH64848.1 - 0.032 13.7 0.0 0.055 13.0 0.0 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain ADH_zinc_N PF00107.26 KXH64849.1 - 1.8e-21 76.5 0.5 2.8e-21 75.9 0.5 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXH64849.1 - 8.9e-11 43.0 0.1 2.5e-10 41.5 0.1 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXH64849.1 - 0.00091 19.1 0.0 0.0021 17.9 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 KXH64849.1 - 0.14 11.5 0.7 0.29 10.6 0.5 1.5 1 1 0 1 1 1 0 short chain dehydrogenase KH_8 PF17903.1 KXH64851.1 - 1.7e-30 105.0 0.0 3.7e-30 103.9 0.0 1.6 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 KXH64851.1 - 0.0044 16.8 0.0 0.011 15.5 0.0 1.7 1 0 0 1 1 1 1 KH domain GATA PF00320.27 KXH64852.1 - 1.9e-15 56.2 2.6 1.1e-14 53.7 2.7 2.1 2 0 0 2 2 2 1 GATA zinc finger DUF834 PF05754.14 KXH64852.1 - 0.006 16.6 2.2 0.015 15.3 2.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF834) ATG16 PF08614.11 KXH64852.1 - 0.014 15.6 9.4 0.014 15.6 9.4 3.0 3 0 0 3 3 3 0 Autophagy protein 16 (ATG16) LcrG PF07216.12 KXH64852.1 - 0.11 12.4 0.3 0.11 12.4 0.3 2.2 2 0 0 2 2 2 0 LcrG protein HOOK PF05622.12 KXH64852.1 - 0.15 10.1 10.1 0.011 13.9 5.1 1.6 2 0 0 2 2 2 0 HOOK protein TF_Zn_Ribbon PF08271.12 KXH64852.1 - 0.26 10.8 0.5 0.45 10.1 0.5 1.3 1 0 0 1 1 1 0 TFIIB zinc-binding Chlam_PMP PF02415.17 KXH64852.1 - 0.79 10.3 5.1 1.2 9.8 1.1 2.9 2 0 0 2 2 2 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Cnn_1N PF07989.11 KXH64852.1 - 1.5 9.0 11.2 18 5.6 0.0 3.4 3 0 0 3 3 3 0 Centrosomin N-terminal motif 1 DUF1296 PF06972.11 KXH64853.1 - 0.03 14.5 0.4 2.5 8.3 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1296) Mit_KHE1 PF10173.9 KXH64854.1 - 2.3e-62 210.5 0.1 2.3e-62 210.5 0.1 1.4 2 0 0 2 2 2 1 Mitochondrial K+-H+ exchange-related Bcl-2_3 PF15286.6 KXH64855.1 - 0.008 16.9 0.0 0.015 16.0 0.0 1.4 1 0 0 1 1 1 1 Apoptosis regulator M11, B cell 2 leukaemia/lymphoma like MARVEL PF01284.23 KXH64855.1 - 0.19 11.8 3.8 0.29 11.2 3.8 1.3 1 0 0 1 1 1 0 Membrane-associating domain Cullin PF00888.22 KXH64856.1 - 3.3e-196 653.6 10.0 4.5e-196 653.2 10.0 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KXH64856.1 - 3.5e-26 91.0 6.5 5.5e-26 90.4 4.6 2.5 2 0 0 2 2 2 1 Cullin protein neddylation domain DUF1803 PF08820.10 KXH64856.1 - 0.14 12.2 1.6 3.4 7.8 0.1 3.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1803) WAC_Acf1_DNA_bd PF10537.9 KXH64856.1 - 0.29 11.7 3.4 0.32 11.6 0.5 2.6 3 0 0 3 3 3 0 ATP-utilising chromatin assembly and remodelling N-terminal DUF3176 PF11374.8 KXH64857.1 - 3.4e-32 110.8 2.1 3.4e-32 110.8 2.1 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) DUF2034 PF10356.9 KXH64858.1 - 3e-29 101.8 0.0 6.3e-15 55.1 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF2034) Mrr_cat PF04471.12 KXH64858.1 - 3.7e-07 30.2 0.0 1.1e-06 28.7 0.0 1.7 2 0 0 2 2 2 1 Restriction endonuclease Med21 PF11221.8 KXH64859.1 - 4.1e-48 163.3 7.1 4.5e-48 163.2 7.1 1.0 1 0 0 1 1 1 1 Subunit 21 of Mediator complex GAS PF13851.6 KXH64859.1 - 0.00029 20.3 4.4 0.063 12.6 0.1 2.1 2 0 0 2 2 2 2 Growth-arrest specific micro-tubule binding Med9 PF07544.13 KXH64859.1 - 0.001 19.1 1.0 0.001 19.1 1.0 3.0 2 1 1 3 3 3 1 RNA polymerase II transcription mediator complex subunit 9 T3SS_needle_E PF08988.10 KXH64859.1 - 0.059 13.5 1.9 0.54 10.4 0.8 2.3 2 0 0 2 2 2 0 Type III secretion system, cytoplasmic E component of needle DUF3802 PF12290.8 KXH64859.1 - 0.074 13.6 1.5 0.17 12.4 1.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3802) Fib_alpha PF08702.10 KXH64859.1 - 0.21 11.8 2.9 0.46 10.7 1.2 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family TMF_DNA_bd PF12329.8 KXH64859.1 - 0.57 10.2 6.9 5.2 7.1 6.9 2.2 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding HIP1_clath_bdg PF16515.5 KXH64859.1 - 1.6 9.4 8.1 1.2 9.8 1.3 2.6 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 HAD_2 PF13419.6 KXH64860.1 - 3.6e-12 46.7 0.0 5.5e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KXH64860.1 - 1.1e-11 45.5 0.0 4.6e-11 43.4 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KXH64860.1 - 0.0017 18.4 0.0 0.003 17.6 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 KXH64860.1 - 0.016 15.6 0.0 0.024 15.0 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Fungal_trans_2 PF11951.8 KXH64864.1 - 3.4e-27 95.3 0.0 4.6e-27 94.8 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH64864.1 - 0.00034 20.7 16.5 0.00063 19.8 16.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Spheroidin PF05541.12 KXH64864.1 - 5.6 4.7 4.8 7.5 4.2 4.8 1.1 1 0 0 1 1 1 0 Entomopoxvirus spheroidin protein Fungal_trans PF04082.18 KXH64866.1 - 3.1e-11 42.8 0.0 6e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH64866.1 - 1.4e-08 34.7 12.4 2.4e-08 33.9 12.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CorA PF01544.18 KXH64867.1 - 6e-06 25.8 0.0 7.4e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF2637 PF10935.8 KXH64868.1 - 0.2 11.5 0.0 0.34 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2637) ADH_N PF08240.12 KXH64869.1 - 1.1e-29 102.5 0.1 1.1e-29 102.5 0.1 1.9 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXH64869.1 - 5.5e-23 81.4 0.2 8.9e-23 80.7 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KXH64869.1 - 5.5e-09 35.8 0.4 8.7e-09 35.2 0.4 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 KXH64869.1 - 2.8e-06 26.8 1.5 4.1e-06 26.3 1.5 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.6 KXH64869.1 - 0.00034 21.7 0.0 0.0014 19.6 0.0 2.1 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Pyr_redox_2 PF07992.14 KXH64869.1 - 0.004 16.4 0.3 0.0082 15.4 0.3 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 KXH64869.1 - 0.0042 16.7 0.1 0.0084 15.7 0.0 1.6 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain HI0933_like PF03486.14 KXH64869.1 - 0.036 12.8 0.4 0.056 12.2 0.4 1.2 1 0 0 1 1 1 0 HI0933-like protein AdoHcyase_NAD PF00670.21 KXH64869.1 - 0.047 13.8 0.5 0.44 10.6 0.3 2.2 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 KXH64869.1 - 0.054 12.9 0.1 0.1 11.9 0.1 1.5 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_25 PF13649.6 KXH64869.1 - 0.1 13.3 0.1 0.2 12.4 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase domain Pyr_redox_3 PF13738.6 KXH64869.1 - 0.11 11.8 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FtsJ PF01728.19 KXH64869.1 - 0.15 12.2 0.1 0.21 11.7 0.1 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase NmrA PF05368.13 KXH64872.1 - 8.9e-06 25.4 1.3 0.013 15.1 0.1 2.0 1 1 1 2 2 2 2 NmrA-like family KR PF08659.10 KXH64872.1 - 0.0002 21.3 0.0 0.00023 21.1 0.0 1.1 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.17 KXH64872.1 - 0.0089 16.6 0.1 0.011 16.3 0.1 1.3 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_10 PF13460.6 KXH64872.1 - 0.011 15.7 0.1 0.022 14.6 0.1 1.5 1 1 1 2 2 2 0 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KXH64872.1 - 0.038 13.1 0.0 0.038 13.1 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DapB_N PF01113.20 KXH64872.1 - 0.055 13.6 0.0 0.071 13.2 0.0 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus IMS PF00817.20 KXH64873.1 - 1.5e-39 135.4 0.0 4.8e-39 133.8 0.0 1.8 2 0 0 2 2 2 1 impB/mucB/samB family zf_UBZ PF18439.1 KXH64873.1 - 4.7e-12 45.3 1.7 1e-11 44.2 1.7 1.6 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger IMS_C PF11799.8 KXH64873.1 - 1.2e-11 45.4 0.2 1.6e-10 41.7 0.0 2.8 4 0 0 4 4 4 1 impB/mucB/samB family C-terminal domain AP_endonuc_2 PF01261.24 KXH64874.1 - 1.1e-07 31.6 0.0 3.5e-07 29.9 0.0 1.8 1 1 0 1 1 1 1 Xylose isomerase-like TIM barrel Mannosidase_ig PF17786.1 KXH64875.1 - 7.4e-17 61.7 0.8 2.5e-16 60.1 0.2 2.2 2 0 0 2 2 2 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 KXH64875.1 - 2.3e-12 47.5 0.7 5.3e-12 46.4 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Ig_mannosidase PF17753.1 KXH64875.1 - 3.8e-06 26.5 0.0 1.1e-05 25.1 0.0 1.8 1 0 0 1 1 1 1 Ig-fold domain Glyco_hydro_2_C PF02836.17 KXH64875.1 - 0.00085 18.5 1.1 0.0072 15.5 1.1 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.18 KXH64875.1 - 0.0013 18.6 0.0 0.0036 17.2 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Ig_GlcNase PF18368.1 KXH64875.1 - 0.017 15.2 0.1 0.12 12.6 0.0 2.4 2 0 0 2 2 2 0 Exo-beta-D-glucosaminidase Ig-fold domain Ras PF00071.22 KXH64876.1 - 7.5e-43 145.9 0.0 1.3e-42 145.1 0.0 1.4 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KXH64876.1 - 5e-30 104.2 0.0 7.4e-30 103.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXH64876.1 - 7.4e-11 41.8 0.0 2.7e-10 40.0 0.0 1.7 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KXH64876.1 - 0.00028 20.9 0.0 0.00054 20.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.6 KXH64876.1 - 0.0025 18.0 0.0 0.0039 17.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain Gtr1_RagA PF04670.12 KXH64876.1 - 0.0048 16.3 0.0 0.0062 15.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KXH64876.1 - 0.017 14.6 0.0 0.024 14.1 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 KXH64876.1 - 0.02 14.4 0.0 0.099 12.2 0.0 2.1 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KXH64876.1 - 0.022 14.7 0.0 0.1 12.5 0.0 2.0 1 1 1 2 2 2 0 RsgA GTPase PduV-EutP PF10662.9 KXH64876.1 - 0.031 14.0 0.0 0.58 9.9 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.6 KXH64876.1 - 0.051 13.8 0.0 0.074 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KXH64876.1 - 0.078 13.3 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KXH64876.1 - 0.1 13.0 0.0 0.17 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 KXH64876.1 - 0.14 12.7 0.0 0.25 11.9 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_7 PF12775.7 KXH64876.1 - 0.15 11.6 0.0 0.23 10.9 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region Tropomodulin PF03250.14 KXH64876.1 - 0.18 11.8 0.0 0.29 11.2 0.0 1.2 1 0 0 1 1 1 0 Tropomodulin adh_short PF00106.25 KXH64877.1 - 1.5e-34 119.2 0.1 1.8e-34 118.9 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXH64877.1 - 1.3e-31 110.0 0.2 1.5e-31 109.8 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH64877.1 - 1.3e-09 38.2 0.4 4.4e-09 36.5 0.4 1.9 1 1 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 KXH64877.1 - 0.0017 17.4 0.1 0.0031 16.6 0.1 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Flu_PB1 PF00602.17 KXH64877.1 - 0.021 13.0 0.3 0.038 12.1 0.0 1.5 2 0 0 2 2 2 0 Influenza RNA-dependent RNA polymerase subunit PB1 LRR_4 PF12799.7 KXH64879.1 - 0.0088 16.4 0.1 32 5.1 0.0 4.0 4 0 0 4 4 4 1 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KXH64879.1 - 0.036 14.0 0.5 0.18 11.7 0.0 2.3 1 1 1 2 2 2 0 F-box-like F-box PF00646.33 KXH64879.1 - 0.059 13.3 1.6 0.069 13.1 0.1 2.0 2 0 0 2 2 2 0 F-box domain F-box_4 PF15966.5 KXH64879.1 - 0.18 11.7 0.1 0.41 10.5 0.1 1.6 1 0 0 1 1 1 0 F-box F-box-like PF12937.7 KXH64880.1 - 0.0041 17.0 0.0 0.0079 16.1 0.0 1.5 1 0 0 1 1 1 1 F-box-like E3_UbLigase_R4 PF13764.6 KXH64880.1 - 0.054 11.7 0.0 0.068 11.3 0.0 1.1 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase UBR4 Mei4 PF13971.6 KXH64880.1 - 0.22 11.0 1.4 0.82 9.1 0.1 2.0 2 0 0 2 2 2 0 Meiosis-specific protein Mei4 Fungal_trans_2 PF11951.8 KXH64881.1 - 9.5e-06 24.7 0.1 1.5e-05 24.0 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain PTR2 PF00854.21 KXH64882.1 - 5e-75 252.8 9.1 6.8e-75 252.3 9.1 1.2 1 0 0 1 1 1 1 POT family MFS_1_like PF12832.7 KXH64882.1 - 0.00011 21.2 0.5 0.0032 16.4 0.3 2.7 1 1 1 2 2 2 1 MFS_1 like family DAP_epimerase PF01678.19 KXH64882.1 - 0.17 12.1 0.0 0.36 11.0 0.0 1.5 1 0 0 1 1 1 0 Diaminopimelate epimerase GFA PF04828.14 KXH64884.1 - 1.6e-09 38.0 0.1 1.6e-09 38.0 0.1 1.6 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme FMO-like PF00743.19 KXH64885.1 - 2e-13 49.6 0.1 7.1e-13 47.8 0.0 1.9 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KXH64885.1 - 1.1e-07 32.0 0.1 7.1e-07 29.4 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXH64885.1 - 1.1e-07 31.4 0.0 1.5e-05 24.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXH64885.1 - 1.1e-06 28.1 0.0 2.3e-06 27.1 0.0 1.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXH64885.1 - 1.9e-06 27.3 0.0 0.00031 20.0 0.0 2.3 2 0 0 2 2 2 2 Thi4 family DAO PF01266.24 KXH64885.1 - 5.2e-06 26.3 2.3 0.014 15.0 0.2 3.6 2 1 1 4 4 4 2 FAD dependent oxidoreductase Mqo PF06039.15 KXH64885.1 - 0.019 13.6 0.0 0.36 9.3 0.0 2.3 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) GIDA PF01134.22 KXH64885.1 - 0.062 12.4 0.9 2.6 7.0 0.1 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Amino_oxidase PF01593.24 KXH64885.1 - 0.2 10.9 0.1 0.6 9.3 0.0 1.9 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase PKHD_C PF18331.1 KXH64886.1 - 1.6e-05 24.8 0.4 6.3 6.9 0.0 3.7 3 0 0 3 3 3 3 PKHD-type hydroxylase C-terminal domain Attacin_N PF03768.15 KXH64886.1 - 0.027 14.6 0.1 62 3.8 0.0 3.2 3 0 0 3 3 3 0 Attacin, N-terminal region TMF_DNA_bd PF12329.8 KXH64886.1 - 0.032 14.2 1.7 13 5.8 0.1 3.1 2 1 0 3 3 3 0 TATA element modulatory factor 1 DNA binding Wzz PF02706.15 KXH64886.1 - 0.042 14.2 2.7 3.4 8.0 0.1 3.4 1 1 3 4 4 4 0 Chain length determinant protein RDM PF11002.8 KXH64886.1 - 0.047 13.7 3.1 81 3.3 0.0 4.8 5 0 0 5 5 5 0 RFPL defining motif (RDM) PSD3 PF07626.11 KXH64886.1 - 0.049 14.1 7.7 15 6.1 0.2 4.4 1 1 4 5 5 5 0 Protein of unknown function (DUF1587) Erythro-docking PF09277.11 KXH64886.1 - 0.075 12.9 11.7 3.3 7.7 1.1 3.3 3 0 0 3 3 3 0 Erythronolide synthase, docking DUF2275 PF10039.9 KXH64886.1 - 0.12 12.5 4.5 1.6 8.8 0.5 2.3 1 1 1 2 2 2 0 Predicted integral membrane protein (DUF2275) RIIa PF02197.17 KXH64886.1 - 0.17 11.6 3.1 25 4.6 0.1 3.3 3 0 0 3 3 3 0 Regulatory subunit of type II PKA R-subunit Sigma54_AID PF00309.20 KXH64886.1 - 0.19 11.6 3.7 12 5.8 0.0 3.3 3 0 0 3 3 3 0 Sigma-54 factor, Activator interacting domain (AID) DUF4404 PF14357.6 KXH64886.1 - 0.84 10.3 8.7 16 6.2 2.1 3.4 1 1 2 3 3 3 0 Domain of unknown function (DUF4404) Trypan_PARP PF05887.11 KXH64886.1 - 0.97 9.4 9.3 13 5.7 1.7 3.1 1 1 2 3 3 3 0 Procyclic acidic repetitive protein (PARP) ThiS PF02597.20 KXH64886.1 - 1.3 9.7 8.8 9.7 6.9 0.5 3.1 1 1 2 3 3 3 0 ThiS family DUF4407 PF14362.6 KXH64886.1 - 2.7 7.3 14.0 6.1 6.1 13.3 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Abhydrolase_1 PF00561.20 KXH64887.1 - 1.3e-18 67.6 0.1 6.5e-16 58.7 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXH64887.1 - 6.7e-11 41.9 0.0 2.2e-10 40.2 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KXH64887.1 - 8e-10 39.7 0.0 1e-09 39.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 KXH64887.1 - 2e-05 24.2 0.2 0.0056 16.2 0.0 2.1 2 0 0 2 2 2 2 Dienelactone hydrolase family FSH1 PF03959.13 KXH64887.1 - 0.0011 18.7 0.0 0.0065 16.2 0.0 2.0 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_4 PF08386.10 KXH64887.1 - 0.0037 17.3 0.0 0.007 16.5 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein BAAT_C PF08840.11 KXH64887.1 - 0.037 13.9 0.1 0.49 10.3 0.0 2.0 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Thioesterase PF00975.20 KXH64887.1 - 0.062 13.4 0.0 0.084 13.0 0.0 1.4 1 1 0 1 1 1 0 Thioesterase domain Peptidase_S9 PF00326.21 KXH64887.1 - 0.068 12.6 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family Esterase PF00756.20 KXH64887.1 - 0.12 12.0 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Putative esterase ADH_N PF08240.12 KXH64888.1 - 1.9e-17 63.1 2.5 2.1e-16 59.8 0.2 2.9 2 2 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXH64888.1 - 3.2e-15 56.3 2.8 3.2e-15 56.3 2.8 2.0 2 1 0 2 2 2 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KXH64888.1 - 2.9e-05 23.6 2.6 4.6e-05 23.0 2.6 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus 2-Hacid_dh_C PF02826.19 KXH64888.1 - 0.00037 19.9 0.4 0.00091 18.6 0.1 1.8 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KXH64888.1 - 0.00045 19.6 1.4 0.00045 19.6 1.4 1.9 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.6 KXH64888.1 - 0.00047 21.2 1.1 0.00066 20.7 0.3 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase DUF5441 PF17513.2 KXH64888.1 - 0.00078 19.2 2.7 0.0012 18.7 2.7 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5441) NAD_binding_2 PF03446.15 KXH64888.1 - 0.0016 18.6 1.8 0.18 12.0 0.0 2.3 1 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase UDPG_MGDP_dh_N PF03721.14 KXH64888.1 - 0.027 14.1 0.1 0.049 13.2 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Ribosom_S12_S23 PF00164.25 KXH64888.1 - 0.038 13.6 0.1 0.29 10.8 0.0 2.4 2 1 1 3 3 3 0 Ribosomal protein S12/S23 Methyltransf_2 PF00891.18 KXH64889.1 - 1e-19 70.7 0.0 1.8e-19 69.9 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_31 PF13847.6 KXH64889.1 - 0.035 13.9 0.0 0.069 12.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain HTH_Tnp_ISL3 PF13542.6 KXH64889.1 - 0.17 11.3 0.0 0.54 9.7 0.0 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 p450 PF00067.22 KXH64890.1 - 2.5e-49 168.3 0.0 3.3e-49 167.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Gly_transf_sug PF04488.15 KXH64891.1 - 3.9e-10 40.2 0.0 6.2e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 KXH64891.1 - 0.065 12.5 0.3 0.16 11.2 0.0 1.7 2 1 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain PS_Dcarbxylase PF02666.15 KXH64892.1 - 8e-46 156.1 0.0 1e-45 155.8 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase MFS_1 PF07690.16 KXH64893.1 - 1.3e-28 100.0 31.4 1.3e-28 100.0 31.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH64893.1 - 1.3e-12 47.3 15.6 2e-12 46.7 14.8 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter AAA PF00004.29 KXH64894.1 - 1.8e-15 57.5 0.0 3.6e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KXH64894.1 - 2.1e-05 25.0 1.2 0.00028 21.3 1.2 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KXH64894.1 - 3.4e-05 24.1 0.6 0.0028 18.0 0.1 2.6 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 KXH64894.1 - 0.031 14.3 0.0 0.096 12.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 KXH64894.1 - 0.062 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain Metal_resist PF13801.6 KXH64894.1 - 1.2 9.3 4.2 29 4.9 0.0 3.1 3 0 0 3 3 3 0 Heavy-metal resistance HMG-CoA_red PF00368.18 KXH64895.1 - 1e-140 469.0 4.6 1.3e-140 468.6 4.6 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HPIH PF13323.6 KXH64895.1 - 2.7e-51 173.5 2.0 4.6e-51 172.8 2.0 1.4 1 0 0 1 1 1 1 N-terminal domain with HPIH motif Sterol-sensing PF12349.8 KXH64895.1 - 9.6e-13 48.2 4.7 4.2e-11 42.9 4.7 2.6 1 1 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 KXH64895.1 - 3.4e-05 22.1 0.9 5.8e-05 21.4 0.9 1.3 1 0 0 1 1 1 1 Patched family Lig_chan PF00060.26 KXH64895.1 - 0.0093 15.8 2.0 1.4 8.7 0.0 2.5 2 0 0 2 2 2 1 Ligand-gated ion channel Isochorismatase PF00857.20 KXH64896.1 - 2.1e-24 86.7 0.1 3.7e-24 85.8 0.1 1.4 1 1 0 1 1 1 1 Isochorismatase family S1-P1_nuclease PF02265.16 KXH64898.1 - 4.8e-63 213.3 0.0 5.5e-63 213.1 0.0 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease ECH_1 PF00378.20 KXH64899.1 - 1.8e-45 155.2 0.0 2.3e-45 154.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXH64899.1 - 3.1e-25 89.4 0.0 7.2e-25 88.2 0.0 1.5 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase NAD_binding_8 PF13450.6 KXH64900.1 - 6.5e-13 48.7 0.1 1.6e-12 47.5 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXH64900.1 - 4.8e-09 36.3 0.0 4.7e-07 29.7 0.0 2.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXH64900.1 - 1.4e-06 27.7 0.1 0.00017 20.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KXH64900.1 - 6.7e-06 25.6 0.8 0.29 10.4 0.0 3.4 3 1 0 3 3 3 2 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 KXH64900.1 - 9.3e-05 22.9 0.1 0.58 10.8 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXH64900.1 - 0.00041 19.6 0.0 0.00068 18.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KXH64900.1 - 0.00053 18.8 0.0 0.033 12.9 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_9 PF13454.6 KXH64900.1 - 0.0011 19.0 0.0 0.0061 16.6 0.0 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.17 KXH64900.1 - 0.002 17.4 0.0 0.0036 16.6 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 KXH64900.1 - 0.072 12.1 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_3 PF01494.19 KXH64900.1 - 0.1 11.8 0.0 0.28 10.4 0.0 1.7 2 0 0 2 2 2 0 FAD binding domain zf-C2H2_2 PF12756.7 KXH64901.1 - 5.8e-24 84.4 2.0 1.3e-23 83.2 2.0 1.5 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) NTP_transf_7 PF07984.12 KXH64901.1 - 0.047 12.9 0.0 0.069 12.4 0.0 1.2 1 0 0 1 1 1 0 Nucleotidyltransferase adh_short PF00106.25 KXH64904.1 - 1.1e-16 60.8 0.1 4.9e-08 32.7 0.0 2.5 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXH64904.1 - 2.3e-12 47.0 0.1 2.3e-07 30.6 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase DUF1582 PF07621.11 KXH64904.1 - 0.059 13.3 0.1 0.13 12.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1582) OmdA PF13376.6 KXH64905.1 - 4.1e-21 74.7 2.2 6.7e-21 74.1 0.9 2.0 2 0 0 2 2 2 1 Bacteriocin-protection, YdeI or OmpD-Associated Phage_tail_2 PF06199.11 KXH64905.1 - 0.12 12.4 0.1 0.21 11.7 0.1 1.3 1 0 0 1 1 1 0 Phage tail tube protein Lipase_GDSL_2 PF13472.6 KXH64907.1 - 7.1e-21 75.4 1.3 1.2e-20 74.6 1.3 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KXH64907.1 - 0.00055 20.0 0.1 0.0024 17.9 0.1 2.0 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase T3SS_needle_E PF08988.10 KXH64908.1 - 0.03 14.4 0.1 0.11 12.7 0.0 2.0 2 0 0 2 2 2 0 Type III secretion system, cytoplasmic E component of needle Herpes_LP PF03363.13 KXH64908.1 - 0.082 12.7 2.5 0.25 11.1 0.3 2.1 2 0 0 2 2 2 0 Herpesvirus leader protein ALMT PF11744.8 KXH64908.1 - 8.4 5.1 6.5 9.6 4.9 6.5 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter SRP_TPR_like PF17004.5 KXH64909.1 - 2.2e-21 76.0 10.6 5.5e-21 74.8 1.5 3.1 2 1 1 3 3 3 1 Putative TPR-like repeat SRP72 PF08492.12 KXH64909.1 - 2.5e-15 56.6 6.9 2.5e-15 56.6 6.9 2.6 2 0 0 2 2 2 1 SRP72 RNA-binding domain TPR_14 PF13428.6 KXH64909.1 - 4.3e-07 30.2 16.9 1.8 9.6 0.0 8.5 8 1 1 9 9 8 2 Tetratricopeptide repeat TPR_2 PF07719.17 KXH64909.1 - 8.1e-07 28.7 13.5 0.033 14.3 0.1 6.5 7 0 0 7 7 7 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KXH64909.1 - 1.8e-05 24.8 2.8 0.0023 18.1 0.4 4.3 4 0 0 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 KXH64909.1 - 2.4e-05 24.5 18.7 6 7.2 0.4 7.1 6 2 1 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 KXH64909.1 - 0.00021 21.7 23.1 3.1 8.4 0.0 6.6 4 2 3 7 7 7 3 Tetratricopeptide repeat SPO22 PF08631.10 KXH64909.1 - 0.00031 20.3 4.2 0.047 13.2 0.3 3.2 2 1 1 3 3 3 1 Meiosis protein SPO22/ZIP4 like TPR_10 PF13374.6 KXH64909.1 - 0.00032 20.4 6.8 1.9 8.5 0.1 5.6 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 KXH64909.1 - 0.0012 18.5 4.6 24 4.9 0.0 5.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.14 KXH64909.1 - 0.0044 17.5 1.2 28 5.7 0.2 5.1 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 KXH64909.1 - 0.0066 17.1 19.2 0.021 15.5 0.7 5.8 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_11 PF13414.6 KXH64909.1 - 0.009 15.7 2.8 0.79 9.5 0.0 4.0 4 0 0 4 4 4 1 TPR repeat TPR_MalT PF17874.1 KXH64909.1 - 0.02 14.3 6.0 0.86 8.9 0.1 3.7 3 2 0 3 3 3 0 MalT-like TPR region TPR_8 PF13181.6 KXH64909.1 - 0.072 13.3 4.1 45 4.6 0.0 5.0 6 0 0 6 6 4 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KXH64909.1 - 0.2 11.7 2.8 40 4.4 0.1 4.1 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.6 KXH64909.1 - 0.32 11.7 9.5 69 4.4 0.2 6.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_9 PF13371.6 KXH64909.1 - 0.68 10.1 12.5 21 5.3 0.0 5.7 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_7 PF13176.6 KXH64909.1 - 2.3 8.5 9.6 1.4e+02 2.9 0.4 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat Sec7 PF01369.20 KXH64910.1 - 6.4e-31 107.4 0.1 9.9e-31 106.8 0.1 1.2 1 0 0 1 1 1 1 Sec7 domain PH PF00169.29 KXH64910.1 - 5.7e-07 30.0 0.1 1.4e-06 28.8 0.1 1.7 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 KXH64910.1 - 2.4e-05 24.7 0.1 5.2e-05 23.6 0.1 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain Steroid_dh PF02544.16 KXH64912.1 - 4.8e-15 55.8 0.1 1.1e-14 54.7 0.1 1.6 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 KXH64912.1 - 0.0016 18.0 0.2 0.004 16.7 0.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.13 KXH64912.1 - 0.011 16.1 0.0 0.044 14.2 0.0 2.1 1 0 0 1 1 1 0 Phospholipid methyltransferase 2OG-FeII_Oxy_2 PF13532.6 KXH64913.1 - 8.8e-06 26.0 0.0 8.3e-05 22.9 0.0 2.2 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Ank_2 PF12796.7 KXH64914.1 - 5.7e-21 74.9 0.0 4.8e-13 49.5 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXH64914.1 - 4.1e-14 52.7 0.0 3e-07 30.8 0.0 4.7 2 2 4 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 KXH64914.1 - 4.2e-12 45.9 2.7 0.00017 21.9 0.1 4.6 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 KXH64914.1 - 3.1e-10 39.4 0.5 0.0027 18.0 0.1 5.3 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 KXH64914.1 - 1.7e-08 34.5 2.5 0.00065 19.9 0.4 3.4 3 1 2 5 5 5 3 Ankyrin repeats (many copies) MMR_HSR1_Xtn PF16897.5 KXH64915.1 - 2.1e-37 127.3 0.5 4.1e-37 126.4 0.5 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 KXH64915.1 - 1.9e-21 76.2 0.1 1.3e-20 73.6 0.1 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KXH64915.1 - 3.7e-10 39.5 0.1 2.8e-09 36.7 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KXH64915.1 - 7.9e-05 22.8 0.1 0.03 14.4 0.0 2.4 1 1 1 2 2 2 2 Dynamin family GTP_EFTU PF00009.27 KXH64915.1 - 0.00066 19.3 0.5 3.6 7.1 0.0 4.1 2 2 0 2 2 2 2 Elongation factor Tu GTP binding domain MeaB PF03308.16 KXH64915.1 - 0.0059 15.6 0.2 0.018 14.0 0.1 1.8 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AIG1 PF04548.16 KXH64915.1 - 0.013 14.9 0.0 0.019 14.3 0.0 1.2 1 0 0 1 1 1 0 AIG1 family Arf PF00025.21 KXH64915.1 - 0.033 13.6 0.3 8 5.9 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KXH64915.1 - 0.035 14.0 1.2 2.8 7.8 0.3 2.9 2 1 0 2 2 2 0 RsgA GTPase Roc PF08477.13 KXH64915.1 - 0.066 13.4 0.1 3.6 7.8 0.0 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 KXH64915.1 - 0.098 12.9 0.1 0.78 10.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KXH64915.1 - 0.2 11.8 0.1 2.1 8.5 0.1 2.1 2 0 0 2 2 2 0 AAA domain His_Phos_2 PF00328.22 KXH64920.1 - 8.7e-07 28.6 2.2 0.00011 21.8 0.1 2.4 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) PDGLE PF13190.6 KXH64920.1 - 0.077 12.9 0.1 0.29 11.1 0.1 2.0 1 0 0 1 1 1 0 PDGLE domain Insulin_TMD PF17870.1 KXH64920.1 - 0.18 11.9 0.4 0.41 10.8 0.4 1.5 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment DUF2613 PF11021.8 KXH64920.1 - 6.1 7.0 10.3 0.32 11.1 2.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2613) Glyco_hydro_61 PF03443.14 KXH64921.1 - 1.9e-63 214.1 0.1 3.9e-63 213.1 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Tyrosinase PF00264.20 KXH64923.1 - 3.6e-48 164.8 0.8 5.1e-48 164.3 0.8 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase SET PF00856.28 KXH64926.1 - 3.1e-08 34.2 0.3 3.1e-08 34.2 0.3 2.4 2 2 0 2 2 2 1 SET domain DUF4438 PF14505.6 KXH64926.1 - 0.096 11.6 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4438) HypA PF01155.19 KXH64926.1 - 0.68 10.0 4.4 0.16 12.0 0.2 2.1 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Ribosomal_L14 PF00238.19 KXH64927.1 - 2.4e-45 153.5 3.1 2.9e-45 153.3 3.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e RNA_POL_M_15KD PF02150.16 KXH64928.1 - 1.1e-11 44.4 3.0 1.1e-11 44.4 3.0 2.9 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit TFIIS_C PF01096.18 KXH64928.1 - 2.7e-07 30.3 0.9 2.7e-07 30.3 0.9 4.5 5 0 0 5 5 5 1 Transcription factor S-II (TFIIS) DZR PF12773.7 KXH64928.1 - 1.3 9.1 13.3 1.9e+02 2.2 1.4 3.7 2 1 1 3 3 3 0 Double zinc ribbon zf-C3HC4_3 PF13920.6 KXH64928.1 - 2.4 8.1 17.1 0.19 11.6 1.0 3.7 3 1 1 4 4 4 0 Zinc finger, C3HC4 type (RING finger) Rotamase PF00639.21 KXH64929.1 - 4.8e-23 81.9 0.0 6.9e-23 81.4 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 KXH64929.1 - 5.5e-16 59.1 0.0 7.9e-16 58.7 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.26 KXH64929.1 - 1.6e-08 34.5 0.6 1.6e-08 34.5 0.6 1.8 2 0 0 2 2 2 1 WW domain Rotamase_2 PF13145.6 KXH64929.1 - 4.2e-05 24.4 0.0 5.7e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW_1 PF18507.1 KXH64929.1 - 0.00082 19.0 0.6 0.0014 18.3 0.6 1.4 1 0 0 1 1 1 1 WW domain LrgB PF04172.16 KXH64930.1 - 1.1e-20 74.1 10.8 1.1e-20 74.1 10.8 2.5 2 1 0 2 2 2 1 LrgB-like family GT87 PF09594.10 KXH64930.1 - 0.0053 16.5 6.7 0.0053 16.5 6.7 3.2 3 2 0 3 3 3 1 Glycosyltransferase family 87 OAD_gamma PF04277.13 KXH64930.1 - 0.051 14.2 2.4 1.8 9.2 0.0 3.4 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain STAT_alpha PF01017.20 KXH64931.1 - 0.007 16.3 16.2 0.024 14.5 9.4 2.9 3 0 0 3 3 3 1 STAT protein, all-alpha domain MamL-1 PF09596.10 KXH64931.1 - 0.014 15.6 0.0 0.085 13.1 0.0 2.4 1 0 0 1 1 1 0 MamL-1 domain HAUS-augmin3 PF14932.6 KXH64931.1 - 0.034 13.7 20.7 0.042 13.4 16.5 2.9 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 UPF0176_N PF17773.1 KXH64931.1 - 0.15 12.5 0.7 1.2 9.5 0.0 2.8 3 0 0 3 3 3 0 UPF0176 acylphosphatase like domain DUF501 PF04417.12 KXH64931.1 - 0.18 11.6 5.7 0.3 10.9 3.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF501) DLP_helical PF18709.1 KXH64931.1 - 0.26 10.5 14.4 0.016 14.4 5.1 2.7 2 1 0 2 2 2 0 Dynamin-like helical domain AKNA PF12443.8 KXH64931.1 - 0.37 11.5 11.9 5.9 7.6 0.1 4.2 4 2 0 4 4 4 0 AT-hook-containing transcription factor Sec34 PF04136.15 KXH64931.1 - 0.42 10.5 15.8 0.45 10.4 1.4 3.1 2 1 0 2 2 2 0 Sec34-like family V_ATPase_I PF01496.19 KXH64931.1 - 0.61 7.9 4.9 1 7.2 4.9 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DivIC PF04977.15 KXH64931.1 - 3.8 7.3 12.0 3.8 7.3 2.7 3.6 2 1 1 3 3 3 0 Septum formation initiator EDR1 PF14381.6 KXH64931.1 - 8.1 6.1 7.8 34 4.1 2.4 2.9 2 1 1 3 3 3 0 Ethylene-responsive protein kinase Le-CTR1 Allexi_40kDa PF05549.11 KXH64931.1 - 8.8 5.8 16.9 2.8 7.4 6.5 2.6 1 1 0 2 2 2 0 Allexivirus 40kDa protein Sugar_tr PF00083.24 KXH64932.1 - 3.2e-89 299.9 21.3 3.8e-89 299.6 21.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH64932.1 - 1e-18 67.4 40.1 2.2e-12 46.6 12.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Peptidase_M24 PF00557.24 KXH64933.1 - 3.5e-52 177.1 0.0 4.8e-52 176.7 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 KXH64933.1 - 8.2e-26 90.1 0.0 1.6e-25 89.3 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Peptidase_C12 PF01088.21 KXH64934.1 - 2.7e-51 174.3 0.0 3.1e-51 174.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 NicO PF03824.16 KXH64935.1 - 6.2e-68 229.2 5.3 9.2e-68 228.6 5.3 1.2 1 0 0 1 1 1 1 High-affinity nickel-transport protein Peptidase_C2 PF00648.21 KXH64937.1 - 1.8e-59 201.2 0.3 4.6e-58 196.6 0.3 2.3 1 1 0 1 1 1 1 Calpain family cysteine protease FAD_binding_2 PF00890.24 KXH64938.1 - 1.7e-80 271.2 0.8 2.2e-80 270.8 0.8 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KXH64938.1 - 2.6e-07 30.5 0.4 0.0002 21.1 0.2 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXH64938.1 - 1.5e-06 27.7 1.3 0.00061 19.1 0.4 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KXH64938.1 - 2e-06 27.4 0.8 3.9e-06 26.5 0.8 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KXH64938.1 - 0.0001 21.6 2.1 0.00059 19.2 0.7 2.2 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 KXH64938.1 - 0.00018 20.4 0.8 0.00018 20.4 0.8 1.6 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.6 KXH64938.1 - 0.00019 21.6 3.0 0.00049 20.3 3.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KXH64938.1 - 0.00087 18.6 1.8 0.0037 16.6 0.7 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KXH64938.1 - 0.031 13.5 0.9 0.059 12.6 0.9 1.4 1 0 0 1 1 1 0 FAD binding domain UPF0227 PF05728.12 KXH64938.1 - 0.18 11.7 0.0 0.32 10.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) GIDA PF01134.22 KXH64938.1 - 0.21 10.7 1.6 7.7 5.5 1.8 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A MFS_1 PF07690.16 KXH64939.1 - 5.2e-19 68.4 18.2 5.2e-19 68.4 18.2 1.7 2 1 0 2 2 2 1 Major Facilitator Superfamily F-box-like PF12937.7 KXH64939.1 - 0.0015 18.4 1.6 0.0028 17.5 0.4 2.3 2 0 0 2 2 2 1 F-box-like FNIP PF05725.12 KXH64939.1 - 0.22 11.7 2.5 16 5.8 0.3 2.9 2 0 0 2 2 2 0 FNIP Repeat DUF4201 PF13870.6 KXH64942.1 - 2.7e-05 24.0 1.7 2.7e-05 24.0 1.7 2.8 2 1 0 3 3 3 1 Domain of unknown function (DUF4201) TRAF_BIRC3_bd PF16673.5 KXH64942.1 - 0.00099 18.9 2.0 0.00099 18.9 2.0 3.2 4 1 1 5 5 5 1 TNF receptor-associated factor BIRC3 binding domain Vac17 PF17321.2 KXH64942.1 - 0.12 11.8 0.4 0.19 11.2 0.4 1.2 1 0 0 1 1 1 0 Vacuole-related protein 17 UvrD_C PF13361.6 KXH64942.1 - 0.12 11.8 2.4 0.16 11.3 2.4 1.2 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain TcpS PF17456.2 KXH64942.1 - 0.26 11.3 2.7 0.47 10.5 2.7 1.4 1 0 0 1 1 1 0 Toxin-coregulated pilus protein S V_ATPase_I PF01496.19 KXH64942.1 - 9.1 4.1 10.4 2.4 6.0 4.4 2.2 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Zn_clus PF00172.18 KXH64943.1 - 5.8e-09 35.9 7.7 1.3e-08 34.8 7.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXH64943.1 - 0.00058 19.0 0.6 0.0011 18.1 0.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Git3 PF11710.8 KXH64944.1 - 9.3e-09 35.3 9.4 9.2e-08 32.1 9.4 2.4 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 DUF2207 PF09972.9 KXH64944.1 - 0.017 13.9 0.6 4.5 5.9 0.0 2.6 2 1 0 3 3 3 0 Predicted membrane protein (DUF2207) OapA_N PF08525.11 KXH64944.1 - 0.099 12.6 0.0 0.24 11.4 0.0 1.7 1 0 0 1 1 1 0 Opacity-associated protein A N-terminal motif DUF872 PF05915.12 KXH64945.1 - 0.023 14.9 0.1 0.042 14.0 0.1 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) DNA_ligase_A_C PF04679.15 KXH64945.1 - 0.03 14.9 0.0 0.061 13.9 0.0 1.5 1 0 0 1 1 1 0 ATP dependent DNA ligase C terminal region DIOX_N PF14226.6 KXH64946.1 - 2.2e-23 83.3 0.0 3.5e-23 82.6 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KXH64946.1 - 4.6e-22 78.4 0.0 1.5e-21 76.8 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Peptidase_M35 PF02102.15 KXH64947.1 - 1.3e-67 228.3 6.6 1.6e-67 227.9 6.6 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.6 KXH64947.1 - 1.7e-38 132.4 0.9 1.7e-38 132.4 0.9 1.8 1 1 1 2 2 2 1 Lysine-specific metallo-endopeptidase HRXXH PF13933.6 KXH64947.1 - 0.0069 16.0 7.2 0.13 11.9 7.2 2.1 1 1 0 1 1 1 1 Putative peptidase family CARDB PF07705.11 KXH64947.1 - 0.049 13.9 0.2 0.2 11.9 0.1 2.1 2 0 0 2 2 2 0 CARDB GFO_IDH_MocA PF01408.22 KXH64948.1 - 2.1e-17 64.0 0.1 3e-17 63.5 0.1 1.2 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Sugar_tr PF00083.24 KXH64949.1 - 9.1e-87 291.8 16.1 1e-86 291.6 16.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH64949.1 - 1.1e-33 116.6 42.8 4.7e-25 88.3 18.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KXH64949.1 - 0.081 11.3 9.2 0.029 12.8 0.3 3.0 3 0 0 3 3 3 0 Fungal trichothecene efflux pump (TRI12) GFO_IDH_MocA PF01408.22 KXH64950.1 - 1.8e-16 61.1 0.0 4.2e-16 59.8 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Methyltransf_25 PF13649.6 KXH64950.1 - 0.081 13.6 0.0 0.2 12.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 KXH64950.1 - 0.21 12.3 0.3 0.55 11.0 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain PAN_1 PF00024.26 KXH64952.1 - 4.3e-12 45.8 20.4 1e-05 25.4 1.2 4.7 3 1 1 4 4 4 4 PAN domain PAN_4 PF14295.6 KXH64952.1 - 1.2e-05 25.1 27.3 0.0081 16.1 0.5 5.0 4 2 0 4 4 4 3 PAN domain PAN_2 PF08276.11 KXH64952.1 - 2.5 8.3 12.2 0.55 10.4 1.4 3.7 3 0 0 3 3 3 0 PAN-like domain Asparaginase_2 PF01112.18 KXH64953.1 - 0.21 10.6 5.5 0.24 10.4 5.5 1.1 1 0 0 1 1 1 0 Asparaginase Glyco_hydro_43 PF04616.14 KXH64954.1 - 3.6e-11 42.9 2.9 6.4e-11 42.1 2.9 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 tRNA-synt_1g PF09334.11 KXH64955.1 - 1.6e-142 474.9 1.1 1.3e-140 468.6 1.1 2.2 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 KXH64955.1 - 2.2e-06 26.2 8.7 0.00047 18.5 0.0 4.0 5 0 0 5 5 5 2 tRNA synthetases class I (I, L, M and V) 3HCDH_N PF02737.18 KXH64955.1 - 0.35 10.7 7.1 0.71 9.7 7.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ADH_N PF08240.12 KXH64957.1 - 9.9e-26 89.8 2.9 1.6e-25 89.1 2.9 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXH64957.1 - 1.1e-14 54.5 0.1 5.9e-14 52.2 0.0 2.1 2 1 1 3 3 3 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KXH64957.1 - 7.3e-05 22.2 0.2 0.00013 21.4 0.2 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 KXH64957.1 - 0.015 15.0 0.0 0.023 14.4 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA ADH_zinc_N_2 PF13602.6 KXH64957.1 - 0.15 13.1 0.0 0.25 12.4 0.0 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase WD40 PF00400.32 KXH64959.1 - 4.5e-31 106.4 11.7 1.1e-06 29.3 0.0 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.7 KXH64959.1 - 4.4e-08 32.9 0.1 1.1e-07 31.7 0.0 1.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KXH64959.1 - 2.4e-07 30.5 0.0 5e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 F-box domain ANAPC4_WD40 PF12894.7 KXH64959.1 - 4.3e-07 30.1 0.6 0.02 15.2 0.0 4.7 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KXH64959.1 - 5.4e-05 22.0 0.6 1.2 7.7 0.0 3.7 1 1 1 4 4 4 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 KXH64959.1 - 0.0035 15.9 0.0 0.0064 15.1 0.0 1.3 1 0 0 1 1 1 1 Cytochrome D1 heme domain Ge1_WD40 PF16529.5 KXH64959.1 - 0.029 13.3 0.1 0.16 10.9 0.0 2.0 2 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_2 PF13360.6 KXH64959.1 - 0.053 13.1 0.1 0.19 11.3 0.1 1.9 1 1 0 1 1 1 0 PQQ-like domain PQQ PF01011.21 KXH64959.1 - 0.14 12.2 0.1 6.5 6.9 0.0 3.5 4 0 0 4 4 4 0 PQQ enzyme repeat Pectate_lyase_3 PF12708.7 KXH64960.1 - 3e-91 305.1 23.1 1.3e-82 276.9 11.4 3.2 3 1 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 KXH64960.1 - 1.4e-05 24.7 1.0 0.18 11.5 0.0 2.8 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Scs3p PF10261.9 KXH64961.1 - 2e-75 253.5 7.5 2.5e-75 253.2 7.5 1.1 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM ATP_transf PF09830.9 KXH64962.1 - 2.3e-20 72.5 0.0 5.2e-20 71.4 0.0 1.6 1 0 0 1 1 1 1 ATP adenylyltransferase Myb_DNA-bind_4 PF13837.6 KXH64963.1 - 0.0061 16.9 0.3 0.016 15.6 0.0 1.9 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KXH64963.1 - 0.081 13.2 0.0 0.28 11.5 0.0 2.0 1 0 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KXH64963.1 - 0.09 13.0 0.1 0.23 11.7 0.1 1.8 1 0 0 1 1 1 0 Myb-like DNA-binding domain p450 PF00067.22 KXH64964.1 - 6.8e-35 120.7 0.0 2.5e-34 118.8 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 Hydrolase_4 PF12146.8 KXH64970.1 - 4e-17 62.3 0.0 1e-12 47.9 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KXH64970.1 - 1.7e-11 44.3 0.1 1.2e-07 31.6 0.1 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold AXE1 PF05448.12 KXH64970.1 - 3.6e-05 22.6 0.0 0.013 14.2 0.0 3.0 2 1 1 3 3 3 1 Acetyl xylan esterase (AXE1) Abhydrolase_6 PF12697.7 KXH64970.1 - 0.00014 22.6 0.1 0.0003 21.4 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF818 PF05677.12 KXH64970.1 - 0.0011 18.0 0.0 0.0016 17.5 0.0 1.1 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) FSH1 PF03959.13 KXH64970.1 - 0.0013 18.5 0.0 0.0039 16.9 0.0 1.7 2 0 0 2 2 2 1 Serine hydrolase (FSH1) Peptidase_S9 PF00326.21 KXH64970.1 - 0.0022 17.5 0.0 0.024 14.1 0.0 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 KXH64970.1 - 0.004 16.7 0.0 0.061 12.9 0.0 2.2 1 1 0 1 1 1 1 Dienelactone hydrolase family BAAT_C PF08840.11 KXH64970.1 - 0.048 13.6 0.0 1 9.2 0.0 2.3 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S15 PF02129.18 KXH64970.1 - 0.066 12.8 0.0 7.8 6.0 0.0 2.2 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_3 PF07859.13 KXH64970.1 - 0.076 12.9 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 KXH64970.1 - 0.15 11.9 0.0 6.4 6.5 0.0 2.3 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase Pex2_Pex12 PF04757.14 KXH64972.1 - 3.3e-40 138.1 0.9 4.1e-40 137.8 0.9 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.6 KXH64972.1 - 1e-11 44.5 8.8 1.6e-11 43.9 8.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXH64972.1 - 4.1e-11 43.0 9.2 6.3e-11 42.4 9.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KXH64972.1 - 3.6e-10 39.6 6.2 5.4e-10 39.0 6.2 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXH64972.1 - 5.5e-10 39.0 6.9 8.4e-10 38.4 6.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KXH64972.1 - 2.3e-07 31.0 5.3 4.1e-07 30.2 5.3 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KXH64972.1 - 2.7e-07 30.5 7.4 5.2e-07 29.6 7.4 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KXH64972.1 - 6.3e-07 29.3 5.9 1e-06 28.6 5.9 1.3 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KXH64972.1 - 1.9e-06 27.6 7.0 3.1e-06 27.0 7.0 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KXH64972.1 - 3.4e-06 27.1 8.0 5.6e-06 26.4 8.0 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_10 PF16685.5 KXH64972.1 - 0.00021 21.4 5.1 0.00035 20.7 5.1 1.3 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-RING_6 PF14835.6 KXH64972.1 - 0.001 18.9 2.5 0.0019 18.0 2.5 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-Nse PF11789.8 KXH64972.1 - 0.0099 15.7 1.4 0.018 14.9 1.4 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.6 KXH64972.1 - 0.04 13.7 6.1 0.085 12.7 6.1 1.5 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 KXH64972.1 - 0.1 12.7 2.5 0.18 11.9 2.5 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF2817 PF10994.8 KXH64972.1 - 0.25 10.7 0.3 0.4 10.0 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2817) zf-RING_11 PF17123.5 KXH64972.1 - 0.38 10.6 3.4 0.78 9.5 3.4 1.6 1 0 0 1 1 1 0 RING-like zinc finger CN_hydrolase PF00795.22 KXH64973.1 - 5.6e-43 147.2 0.0 7.9e-43 146.7 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.17 KXH64973.1 - 1.3e-22 80.1 0.0 6.5e-22 77.8 0.0 2.0 1 1 0 1 1 1 1 NAD synthase Dioxygenase_C PF00775.21 KXH64974.1 - 7.5e-07 28.8 0.0 1.3e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Dioxygenase WSC PF01822.19 KXH64975.1 - 7.7e-85 279.2 83.6 4.4e-17 62.1 5.7 5.6 5 0 0 5 5 5 5 WSC domain Glyoxal_oxid_N PF07250.11 KXH64975.1 - 1e-24 87.1 0.0 2.3e-24 85.9 0.0 1.6 1 0 0 1 1 1 1 Glyoxal oxidase N-terminus DUF1929 PF09118.11 KXH64975.1 - 2.9e-22 78.8 0.0 6.9e-22 77.5 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_2 PF07646.15 KXH64975.1 - 0.012 15.5 0.0 6.3 6.9 0.3 3.9 2 1 1 3 3 3 0 Kelch motif SCIMP PF15050.6 KXH64976.1 - 0.076 13.5 1.9 0.17 12.4 1.9 1.5 1 0 0 1 1 1 0 SCIMP protein bZIP_1 PF00170.21 KXH64976.1 - 1.1 9.4 7.4 2.7 8.2 7.4 1.6 1 1 0 1 1 1 0 bZIP transcription factor RRN3 PF05327.11 KXH64977.1 - 4.4e-173 576.8 0.0 4.4e-173 576.8 0.0 1.6 2 0 0 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 IBN_N PF03810.19 KXH64977.1 - 0.067 13.1 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 Importin-beta N-terminal domain PAC3 PF10178.9 KXH64977.1 - 0.095 12.9 0.0 0.3 11.3 0.0 1.8 1 0 0 1 1 1 0 Proteasome assembly chaperone 3 Sigma70_ner PF04546.13 KXH64977.1 - 2.9 7.7 7.3 6.4 6.6 1.2 2.5 2 0 0 2 2 2 0 Sigma-70, non-essential region CBFD_NFYB_HMF PF00808.23 KXH64978.1 - 1.7e-29 101.9 1.0 2.4e-29 101.4 1.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KXH64978.1 - 2.1e-06 28.1 0.0 3.5e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.16 KXH64978.1 - 0.0014 18.6 0.0 0.002 18.1 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.13 KXH64978.1 - 0.0019 18.1 0.1 0.0033 17.4 0.1 1.3 1 0 0 1 1 1 1 Bromodomain associated CENP-T_C PF15511.6 KXH64978.1 - 0.0028 17.8 0.0 0.0037 17.4 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TFIID_20kDa PF03847.13 KXH64978.1 - 0.062 13.8 0.0 0.11 13.0 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Prefoldin_2 PF01920.20 KXH64979.1 - 3.4e-24 84.8 11.1 4.1e-24 84.6 11.1 1.1 1 0 0 1 1 1 1 Prefoldin subunit IIGP PF05049.13 KXH64979.1 - 0.013 14.6 1.0 0.015 14.4 1.0 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) DUF2205 PF10224.9 KXH64979.1 - 0.033 14.2 2.3 0.033 14.2 2.3 2.1 2 0 0 2 2 2 0 Short coiled-coil protein DUF4757 PF15949.5 KXH64979.1 - 0.048 14.1 3.6 0.073 13.5 3.6 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4757) MIP-T3_C PF17749.1 KXH64979.1 - 0.069 13.1 8.5 0.08 12.9 0.6 2.0 1 1 1 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region Golgin_A5 PF09787.9 KXH64979.1 - 0.083 12.3 8.7 0.086 12.3 8.7 1.0 1 0 0 1 1 1 0 Golgin subfamily A member 5 RUN PF02759.19 KXH64979.1 - 0.086 12.8 0.2 0.11 12.5 0.2 1.2 1 0 0 1 1 1 0 RUN domain SLATT_1 PF18181.1 KXH64979.1 - 0.32 10.9 2.1 0.5 10.3 0.5 1.9 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 DUF4795 PF16043.5 KXH64979.1 - 0.7 9.5 8.6 0.38 10.3 1.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) Cmc1 PF08583.10 KXH64980.1 - 1.1e-15 57.3 4.0 1.4e-15 57.0 4.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like bZIP_1 PF00170.21 KXH64980.1 - 0.31 11.2 9.0 0.49 10.5 9.0 1.2 1 0 0 1 1 1 0 bZIP transcription factor Tmemb_14 PF03647.13 KXH64981.1 - 4.2e-24 85.1 5.3 4.7e-24 84.9 5.3 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C Aim19 PF10315.9 KXH64981.1 - 0.09 13.1 0.1 0.72 10.2 0.1 2.2 1 1 0 1 1 1 0 Altered inheritance of mitochondria protein 19 DAD PF02109.16 KXH64982.1 - 1.4e-50 170.1 2.7 1.7e-50 169.9 2.7 1.1 1 0 0 1 1 1 1 DAD family DUF1180 PF06679.12 KXH64982.1 - 0.034 14.6 2.8 0.048 14.1 2.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) NifW PF03206.14 KXH64982.1 - 0.19 12.2 0.0 0.34 11.4 0.0 1.4 1 0 0 1 1 1 0 Nitrogen fixation protein NifW Tail_spike_N PF18668.1 KXH64982.1 - 0.8 9.6 3.4 0.29 11.0 0.6 1.7 2 0 0 2 2 2 0 Tail spike TSP1/Gp66 receptor binding N-terminal domain GRASP55_65 PF04495.14 KXH64983.1 - 8e-47 159.0 0.0 1e-45 155.4 0.0 2.0 1 1 1 2 2 2 1 GRASP55/65 PDZ-like domain PDZ_6 PF17820.1 KXH64983.1 - 8.1e-06 25.6 0.0 0.15 11.9 0.0 2.5 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 KXH64983.1 - 0.053 13.9 0.0 12 6.4 0.0 2.7 3 0 0 3 3 3 0 PDZ domain PDZ_2 PF13180.6 KXH64983.1 - 0.09 13.1 0.0 0.24 11.8 0.0 1.7 2 0 0 2 2 2 0 PDZ domain Methyltransf_15 PF09445.10 KXH64984.1 - 7.3e-47 159.0 0.0 1e-46 158.6 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Met_10 PF02475.16 KXH64984.1 - 3.4e-05 23.7 0.0 3.6e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Cons_hypoth95 PF03602.15 KXH64984.1 - 0.0016 18.1 0.0 0.0028 17.3 0.0 1.4 1 1 0 1 1 1 1 Conserved hypothetical protein 95 UPF0020 PF01170.18 KXH64984.1 - 0.059 13.0 0.0 0.14 11.8 0.0 1.6 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_25 PF13649.6 KXH64984.1 - 0.09 13.5 0.0 0.21 12.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_5 PF01795.19 KXH64984.1 - 0.2 11.1 0.0 0.27 10.7 0.0 1.1 1 0 0 1 1 1 0 MraW methylase family Dopey_N PF04118.14 KXH64985.1 - 5.7e-119 396.8 0.0 2.1e-118 394.9 0.0 2.0 2 0 0 2 2 2 1 Dopey, N-terminal Mon1 PF03164.14 KXH64986.1 - 1.6e-151 505.0 0.0 1.9e-151 504.7 0.0 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 CDC45 PF02724.14 KXH64987.1 - 0.069 11.4 7.3 0.1 10.9 7.3 1.5 1 0 0 1 1 1 0 CDC45-like protein Noggin PF05806.12 KXH64987.1 - 0.4 10.6 3.1 0.98 9.3 3.1 1.6 1 0 0 1 1 1 0 Noggin FlxA PF14282.6 KXH64987.1 - 6.1 6.9 14.1 0.036 14.1 3.7 2.3 2 0 0 2 2 2 0 FlxA-like protein Thioredoxin PF00085.20 KXH64989.1 - 3.3e-63 210.1 8.7 2.5e-31 107.7 0.1 4.0 4 0 0 4 4 4 3 Thioredoxin Thioredoxin_6 PF13848.6 KXH64989.1 - 2.7e-48 164.3 1.6 2.2e-36 125.5 0.2 3.7 2 2 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KXH64989.1 - 8.2e-11 42.1 0.1 0.0014 18.9 0.0 4.3 3 2 1 4 4 4 2 Thioredoxin-like Thioredoxin_7 PF13899.6 KXH64989.1 - 2.4e-09 37.2 0.1 0.0017 18.5 0.0 3.1 3 0 0 3 3 2 2 Thioredoxin-like Thioredoxin_2 PF13098.6 KXH64989.1 - 4.4e-09 36.8 1.0 0.0011 19.4 0.0 3.3 2 1 0 2 2 2 2 Thioredoxin-like domain OST3_OST6 PF04756.13 KXH64989.1 - 1.2e-08 34.7 2.6 0.0094 15.3 0.0 3.2 2 1 1 3 3 3 2 OST3 / OST6 family, transporter family Calsequestrin PF01216.17 KXH64989.1 - 3.7e-08 32.8 0.8 3.7e-08 32.8 0.8 2.7 1 1 1 3 3 3 1 Calsequestrin AhpC-TSA PF00578.21 KXH64989.1 - 4.2e-08 33.1 1.2 0.0061 16.5 0.1 3.0 3 0 0 3 3 3 2 AhpC/TSA family Redoxin PF08534.10 KXH64989.1 - 1.5e-06 28.0 2.2 0.0034 17.1 0.0 3.3 3 1 0 3 3 3 2 Redoxin Thioredoxin_3 PF13192.6 KXH64989.1 - 0.0089 16.1 0.2 0.049 13.7 0.1 2.3 2 0 0 2 2 2 1 Thioredoxin domain DSBA PF01323.20 KXH64989.1 - 0.028 14.2 0.3 13 5.5 0.0 4.0 3 1 0 3 3 3 0 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 KXH64989.1 - 1.5 9.0 10.8 10 6.2 2.2 4.2 3 2 0 3 3 3 0 Thioredoxin TraF PF13728.6 KXH64989.1 - 9.5 6.0 8.2 14 5.4 0.0 3.2 2 1 1 3 3 3 0 F plasmid transfer operon protein CENP-Q PF13094.6 KXH64990.1 - 0.029 14.6 0.3 0.038 14.2 0.3 1.1 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Trimer_CC PF08954.11 KXH64990.1 - 0.031 13.8 1.3 0.12 11.9 0.2 2.1 2 0 0 2 2 2 0 Trimerisation motif DUF1664 PF07889.12 KXH64990.1 - 0.07 13.2 0.0 0.092 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) zf-HIT PF04438.16 KXH64991.1 - 1.1e-09 38.0 5.1 1.6e-09 37.4 5.1 1.3 1 0 0 1 1 1 1 HIT zinc finger TrkH PF02386.16 KXH64994.1 - 4.1e-90 302.6 15.4 1.2e-86 291.1 3.2 2.2 2 0 0 2 2 2 2 Cation transport protein DUF4451 PF14616.6 KXH65003.1 - 1.2e-23 83.6 0.1 1.2e-23 83.6 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4451) F-box PF00646.33 KXH65004.1 - 3.9e-08 33.0 0.6 8.2e-08 31.9 0.6 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KXH65004.1 - 2.2e-05 24.2 0.3 5.3e-05 23.0 0.3 1.6 1 0 0 1 1 1 1 F-box-like RNA_pol_3_Rpc31 PF11705.8 KXH65005.1 - 0.06 13.6 13.7 3.7 7.7 12.9 2.4 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 DUF4148 PF13663.6 KXH65005.1 - 0.25 11.5 1.6 0.55 10.5 1.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) DNA_pol_phi PF04931.13 KXH65005.1 - 0.78 7.8 10.7 1.2 7.1 10.7 1.2 1 0 0 1 1 1 0 DNA polymerase phi Methyltransf_11 PF08241.12 KXH65006.1 - 0.0023 18.5 0.0 0.0056 17.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH65006.1 - 0.013 16.2 0.0 0.029 15.1 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain SWIRM-assoc_2 PF16496.5 KXH65010.1 - 0.00055 18.9 0.7 0.00055 18.9 0.7 2.1 2 0 0 2 2 2 1 SWIRM-associated domain at the N-terminal PTCB-BRCT PF12738.7 KXH65010.1 - 0.19 11.7 0.1 6.8 6.7 0.1 2.3 2 0 0 2 2 2 0 twin BRCT domain DAHP_synth_2 PF01474.16 KXH65013.1 - 1.1e-201 670.1 0.0 1.3e-201 669.9 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family Amidase PF01425.21 KXH65014.1 - 2.8e-94 316.6 0.0 4.7e-94 315.9 0.0 1.3 1 1 0 1 1 1 1 Amidase UPF0180 PF03698.13 KXH65014.1 - 0.14 12.4 0.0 0.32 11.2 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0180) Methyltransf_25 PF13649.6 KXH65015.1 - 1.2e-13 51.5 0.0 5.7e-13 49.4 0.0 2.1 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH65015.1 - 2.1e-12 47.1 0.0 2.6e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH65015.1 - 1.3e-08 35.3 0.0 8.5e-08 32.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.19 KXH65015.1 - 3.6e-07 30.2 0.0 7.1e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.12 KXH65015.1 - 3.1e-06 27.8 0.0 6.5e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXH65015.1 - 8.1e-05 22.2 0.0 0.00013 21.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 KXH65015.1 - 0.0001 22.2 0.0 0.00015 21.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXH65015.1 - 0.00048 19.5 0.0 0.00087 18.7 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 KXH65015.1 - 0.00054 20.0 0.0 0.00075 19.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 KXH65015.1 - 0.0014 18.3 0.0 0.03 14.0 0.0 2.3 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 PrmA PF06325.13 KXH65015.1 - 0.0017 17.8 0.2 0.0028 17.1 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) RrnaAD PF00398.20 KXH65015.1 - 0.023 13.8 0.0 0.032 13.3 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_18 PF12847.7 KXH65015.1 - 0.023 14.6 0.0 0.037 13.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_9 PF08003.11 KXH65015.1 - 0.032 13.1 0.0 0.058 12.3 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1698) NAD_binding_6 PF08030.12 KXH65016.1 - 1.4e-23 83.7 0.0 2.1e-23 83.1 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KXH65016.1 - 1.1e-22 80.2 0.0 2.4e-22 79.1 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 KXH65016.1 - 1.6e-18 67.0 10.5 1.6e-18 67.0 10.5 2.3 1 1 1 2 2 2 1 Ferric reductase like transmembrane component Myosin_head PF00063.21 KXH65018.1 - 8.9e-239 794.2 2.5 1.1e-238 793.9 2.5 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 KXH65018.1 - 1.7e-48 164.8 0.0 3.6e-48 163.7 0.0 1.6 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding SH3_1 PF00018.28 KXH65018.1 - 9.9e-13 47.5 0.2 2.5e-12 46.2 0.2 1.8 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KXH65018.1 - 1e-11 44.5 0.1 2.5e-11 43.2 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KXH65018.1 - 6.2e-09 35.4 0.0 1.7e-08 34.0 0.0 1.9 1 0 0 1 1 1 1 Variant SH3 domain F-box-like PF12937.7 KXH65018.1 - 5.6e-07 29.4 0.2 5.6e-07 29.4 0.2 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KXH65018.1 - 5.5e-06 26.1 0.3 1.3e-05 25.0 0.3 1.6 1 0 0 1 1 1 1 F-box domain IQ PF00612.27 KXH65018.1 - 0.011 15.4 10.0 0.27 11.1 2.4 2.8 1 1 1 2 2 2 0 IQ calmodulin-binding motif AAA_22 PF13401.6 KXH65018.1 - 0.063 13.6 0.0 0.21 11.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KXH65018.1 - 0.13 12.6 0.0 0.5 10.7 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain DUF4913 PF16259.5 KXH65018.1 - 0.18 11.9 0.9 0.54 10.3 0.9 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4913) Hpr_kinase_C PF07475.12 KXH65018.1 - 0.21 11.1 0.3 8.2 5.9 0.0 2.3 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain DHHC PF01529.20 KXH65019.1 - 9.6e-30 103.4 1.8 1.8e-29 102.5 1.8 1.4 1 0 0 1 1 1 1 DHHC palmitoyltransferase Transglut_core3 PF13471.6 KXH65019.1 - 0.088 12.7 0.7 0.23 11.4 0.7 1.7 1 0 0 1 1 1 0 Transglutaminase-like superfamily Glyco_transf_90 PF05686.12 KXH65020.1 - 1e-06 27.9 0.4 0.0031 16.5 0.2 3.5 2 1 0 2 2 2 2 Glycosyl transferase family 90 Phage_holin_3_3 PF16083.5 KXH65020.1 - 0.26 11.4 1.7 5.9 7.1 0.0 3.2 3 0 0 3 3 3 0 LydA holin phage, holin superfamily III Aldose_epim PF01263.20 KXH65021.1 - 1.4e-20 73.8 0.0 1.7e-20 73.5 0.0 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase PalH PF08733.10 KXH65028.1 - 1.3e-110 369.5 0.5 1.7e-110 369.1 0.5 1.1 1 0 0 1 1 1 1 PalH/RIM21 CAAD PF14159.6 KXH65028.1 - 0.081 12.8 0.6 0.25 11.2 0.1 2.0 2 0 0 2 2 2 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase MRP-L47 PF06984.13 KXH65033.1 - 6.6e-24 83.8 0.5 1.3e-23 82.9 0.5 1.5 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) GDI PF00996.18 KXH65034.1 - 5.7e-195 647.9 0.0 6.4e-195 647.7 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.6 KXH65034.1 - 0.008 16.4 0.0 0.019 15.2 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KXH65034.1 - 0.11 13.1 0.3 0.96 10.1 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NOG1_N PF17835.1 KXH65035.1 - 4.5e-49 166.5 0.8 7.9e-49 165.7 0.0 1.9 2 0 0 2 2 2 1 NOG1 N-terminal helical domain NOGCT PF08155.11 KXH65035.1 - 1.7e-28 98.3 1.3 4.2e-28 97.1 1.3 1.7 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.14 KXH65035.1 - 4.2e-26 90.5 0.7 9.7e-26 89.3 0.7 1.7 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.23 KXH65035.1 - 6.4e-15 55.2 0.0 1.5e-14 54.1 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KXH65035.1 - 2.8e-08 33.5 0.0 5.2e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B Gtr1_RagA PF04670.12 KXH65035.1 - 0.0045 16.4 0.1 0.0076 15.6 0.1 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 KXH65035.1 - 0.027 14.8 0.1 0.19 12.1 0.1 2.6 1 1 0 1 1 1 0 AAA ATPase domain MMR_HSR1_Xtn PF16897.5 KXH65035.1 - 0.035 14.1 0.0 0.095 12.7 0.0 1.7 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain RsgA_GTPase PF03193.16 KXH65035.1 - 0.057 13.3 3.4 0.29 11.0 0.1 3.0 3 1 0 3 3 3 0 RsgA GTPase Dynamin_N PF00350.23 KXH65035.1 - 2.9 7.9 8.4 2 8.5 0.0 3.1 4 0 0 4 4 4 0 Dynamin family Pribosyltran PF00156.27 KXH65036.1 - 1e-15 57.6 0.4 1.6e-15 56.9 0.4 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KXH65036.1 - 0.11 11.9 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Acetyltransf_10 PF13673.7 KXH65037.1 - 8.2e-09 35.5 0.1 1.5e-08 34.6 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXH65037.1 - 2.5e-08 34.1 0.0 3.9e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXH65037.1 - 4.2e-07 30.3 0.0 6.4e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KXH65037.1 - 0.069 13.3 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Asp_protease PF09668.10 KXH65038.1 - 2.3e-59 198.6 0.4 3.3e-59 198.1 0.4 1.2 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KXH65038.1 - 6.1e-24 84.4 0.1 1.2e-23 83.4 0.1 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KXH65038.1 - 1.5e-11 44.8 0.1 2.9e-11 43.9 0.1 1.5 1 0 0 1 1 1 1 Aspartyl protease ubiquitin PF00240.23 KXH65038.1 - 5.9e-10 38.7 0.0 1.3e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 KXH65038.1 - 1e-09 38.1 0.1 2.6e-09 36.8 0.1 1.7 1 0 0 1 1 1 1 UBA/TS-N domain RVP PF00077.20 KXH65038.1 - 0.00014 22.1 0.0 0.00041 20.6 0.0 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP_2 PF08284.11 KXH65038.1 - 0.00031 20.5 0.0 0.00051 19.8 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Rad60-SLD PF11976.8 KXH65038.1 - 0.0022 17.8 0.1 0.0054 16.5 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like CUE PF02845.16 KXH65038.1 - 0.04 13.6 0.0 1.2 8.9 0.0 2.8 2 0 0 2 2 2 0 CUE domain TBK1_ULD PF18396.1 KXH65038.1 - 0.1 12.6 0.1 0.42 10.6 0.1 2.1 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain Methyltransf_8 PF05148.15 KXH65039.1 - 1.7e-58 198.1 0.0 3.4e-57 193.8 0.0 2.7 3 0 0 3 3 3 1 Hypothetical methyltransferase Methyltransf_11 PF08241.12 KXH65039.1 - 4.4e-05 24.1 0.0 0.00016 22.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH65039.1 - 0.00068 20.3 0.0 0.031 15.0 0.0 2.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH65039.1 - 0.0097 15.7 0.1 1 9.1 0.1 2.3 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXH65039.1 - 0.02 14.5 0.0 2.1 7.9 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_32 PF13679.6 KXH65039.1 - 0.042 13.9 0.0 0.042 13.9 0.0 3.2 2 1 0 2 2 2 0 Methyltransferase domain Fungal_trans_2 PF11951.8 KXH65040.1 - 1e-17 64.0 0.5 5.1e-11 42.0 0.1 3.1 3 0 0 3 3 3 3 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH65040.1 - 3.5e-08 33.4 11.5 5.9e-08 32.7 11.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Proteasome PF00227.26 KXH65041.1 - 1.3e-56 191.1 0.1 1.7e-56 190.7 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KXH65041.1 - 1.8e-12 46.7 0.0 3.6e-12 45.7 0.0 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature GCP_N_terminal PF17681.1 KXH65042.1 - 4.3e-63 213.8 0.0 6.7e-63 213.1 0.0 1.2 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 KXH65042.1 - 3.5e-56 190.9 0.8 5.4e-56 190.3 0.0 1.6 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal YqeY PF09424.10 KXH65043.1 - 2.6e-24 85.9 7.2 3.2e-24 85.6 7.2 1.1 1 0 0 1 1 1 1 Yqey-like protein DUF2017 PF09438.10 KXH65043.1 - 0.0028 17.6 4.9 0.0028 17.6 4.9 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF2017) Sun2_CC2 PF18580.1 KXH65043.1 - 0.15 12.3 1.7 0.65 10.3 0.4 2.4 2 0 0 2 2 2 0 SUN2 coiled coil domain 2 IFRD PF05004.13 KXH65048.1 - 3e-70 236.8 4.2 4e-70 236.4 4.2 1.2 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) HEAT_EZ PF13513.6 KXH65048.1 - 1.7e-06 28.4 0.1 0.00083 19.8 0.0 4.4 5 0 0 5 5 5 1 HEAT-like repeat HEAT_2 PF13646.6 KXH65048.1 - 0.0026 18.1 0.1 0.082 13.3 0.0 2.9 2 1 0 2 2 2 1 HEAT repeats HEAT PF02985.22 KXH65048.1 - 0.031 14.5 0.0 1.3 9.5 0.0 3.1 3 0 0 3 3 3 0 HEAT repeat POX PF07526.11 KXH65048.1 - 0.041 14.5 1.5 0.27 11.8 0.5 2.4 2 0 0 2 2 2 0 Associated with HOX Adaptin_N PF01602.20 KXH65048.1 - 0.085 11.4 0.0 0.24 9.9 0.0 1.7 1 1 0 1 1 1 0 Adaptin N terminal region Arm PF00514.23 KXH65048.1 - 0.15 12.2 0.1 7.2 6.8 0.0 2.9 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat FHA PF00498.26 KXH65049.1 - 2.6e-11 43.7 0.0 6.9e-11 42.3 0.0 1.8 1 0 0 1 1 1 1 FHA domain Sulfotransfer_4 PF17784.1 KXH65050.1 - 1.2e-53 182.1 0.0 1.4e-53 181.9 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KXH65050.1 - 2.1e-05 25.0 0.6 0.00089 19.7 0.0 2.5 2 1 1 3 3 3 2 Sulfotransferase family ketoacyl-synt PF00109.26 KXH65051.1 - 2.9e-41 141.7 2.7 6.2e-41 140.6 2.7 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 KXH65051.1 - 9.4e-38 130.5 0.2 1.8e-37 129.6 0.2 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KXH65051.1 - 4.1e-33 113.9 0.0 1.1e-32 112.5 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.20 KXH65051.1 - 1.9e-23 83.8 1.7 5.3e-21 75.8 0.2 3.7 3 1 0 3 3 3 1 Thioesterase domain PS-DH PF14765.6 KXH65051.1 - 5.9e-19 68.4 0.1 1e-18 67.7 0.1 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase PP-binding PF00550.25 KXH65051.1 - 5.5e-10 39.4 0.3 1.4e-09 38.1 0.3 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site KAsynt_C_assoc PF16197.5 KXH65051.1 - 2.9e-07 30.9 0.0 8.7e-07 29.4 0.0 1.9 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Abhydrolase_6 PF12697.7 KXH65051.1 - 0.0012 19.5 1.0 0.07 13.7 0.1 2.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Thiolase_N PF00108.23 KXH65051.1 - 0.0027 17.1 0.6 0.0071 15.7 0.2 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain MFS_1 PF07690.16 KXH65080.1 - 5.6e-08 32.1 4.0 6.1e-08 32.0 4.0 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily EMC1_C PF07774.13 KXH65081.1 - 3.9e-77 258.7 0.0 6.4e-77 258.0 0.0 1.3 1 0 0 1 1 1 1 ER membrane protein complex subunit 1, C-terminal PQQ_2 PF13360.6 KXH65081.1 - 1.6e-20 73.8 6.1 3.5e-18 66.0 2.6 2.7 3 0 0 3 3 3 2 PQQ-like domain PQQ PF01011.21 KXH65081.1 - 3.4 7.8 6.7 16 5.6 0.1 4.7 5 0 0 5 5 5 0 PQQ enzyme repeat Isy1 PF06246.12 KXH65082.1 - 4.1e-90 301.8 0.9 5.1e-90 301.5 0.9 1.0 1 0 0 1 1 1 1 Isy1-like splicing family Ribosomal_S14 PF00253.21 KXH65083.1 - 4.7e-23 80.7 0.8 1.2e-21 76.2 0.6 2.1 2 0 0 2 2 2 2 Ribosomal protein S14p/S29e Fungal_trans PF04082.18 KXH65086.1 - 1.9e-09 36.9 0.3 6.4e-09 35.2 0.2 1.9 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH65086.1 - 3.5e-05 23.8 10.0 6.1e-05 23.1 10.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fcf1 PF04900.12 KXH65087.1 - 1.1e-32 112.3 0.2 3.3e-32 110.8 0.1 1.8 2 0 0 2 2 2 1 Fcf1 PIN_9 PF18477.1 KXH65087.1 - 1.3e-10 41.6 0.0 6.5e-10 39.3 0.0 1.9 2 0 0 2 2 2 1 PIN like domain GCV_T PF01571.21 KXH65087.1 - 0.12 11.7 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Aminomethyltransferase folate-binding domain ABC_membrane PF00664.23 KXH65089.1 - 4.7e-54 183.9 35.8 2.8e-33 115.8 16.4 3.3 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.27 KXH65089.1 - 7.4e-48 162.5 0.0 3.1e-27 95.8 0.0 2.8 2 0 0 2 2 2 2 ABC transporter AAA_16 PF13191.6 KXH65089.1 - 1e-05 26.0 0.0 0.21 12.0 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.19 KXH65089.1 - 2.4e-05 23.9 0.3 1.3 8.4 0.2 3.6 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.12 KXH65089.1 - 4.6e-05 22.8 0.0 0.0048 16.2 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin MMR_HSR1 PF01926.23 KXH65089.1 - 4.8e-05 23.4 1.8 0.054 13.6 0.1 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KXH65089.1 - 0.00013 22.0 1.1 0.067 13.1 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 KXH65089.1 - 0.00038 20.1 1.4 0.46 10.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_30 PF13604.6 KXH65089.1 - 0.001 18.8 1.4 0.48 10.1 0.1 2.6 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 KXH65089.1 - 0.0011 19.5 4.5 0.32 11.5 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_21 PF13304.6 KXH65089.1 - 0.0017 18.2 0.6 1.8 8.3 0.1 2.8 3 0 0 3 3 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KXH65089.1 - 0.0037 17.5 0.8 3.7 7.8 0.0 3.1 2 1 0 2 2 2 1 AAA domain DUF87 PF01935.17 KXH65089.1 - 0.0051 16.9 2.3 0.14 12.2 0.4 2.4 2 0 0 2 2 2 1 Helicase HerA, central domain TrwB_AAD_bind PF10412.9 KXH65089.1 - 0.0052 15.8 0.3 0.64 8.9 0.0 2.4 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain AAA_28 PF13521.6 KXH65089.1 - 0.028 14.7 0.9 0.13 12.5 0.0 2.5 3 0 0 3 3 2 0 AAA domain Roc PF08477.13 KXH65089.1 - 0.029 14.6 0.1 6.5 7.0 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_15 PF13175.6 KXH65089.1 - 0.04 13.6 0.2 0.84 9.3 0.1 2.5 2 0 0 2 2 2 0 AAA ATPase domain AAA_7 PF12775.7 KXH65089.1 - 0.042 13.4 0.7 2.1 7.8 0.1 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region MeaB PF03308.16 KXH65089.1 - 0.05 12.6 1.5 0.58 9.1 0.2 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB SRP54 PF00448.22 KXH65089.1 - 0.072 12.7 0.5 0.64 9.6 0.1 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain FtsK_SpoIIIE PF01580.18 KXH65089.1 - 0.072 12.4 0.0 7.3 5.9 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family NACHT PF05729.12 KXH65089.1 - 0.08 12.9 0.7 0.58 10.0 0.0 2.3 2 0 0 2 2 2 0 NACHT domain AAA_18 PF13238.6 KXH65089.1 - 0.086 13.4 0.0 6.6 7.3 0.0 2.8 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 KXH65089.1 - 0.086 12.9 3.9 0.71 9.9 0.3 2.6 2 0 0 2 2 2 0 Dynamin family ATP_bind_1 PF03029.17 KXH65089.1 - 0.51 10.1 2.1 13 5.5 0.3 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein NB-ARC PF00931.22 KXH65089.1 - 0.84 8.8 2.1 14 4.8 0.6 2.3 2 0 0 2 2 2 0 NB-ARC domain cobW PF02492.19 KXH65089.1 - 1.2 8.7 3.2 1.7 8.2 0.3 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DEAD PF00270.29 KXH65091.1 - 5.7e-49 166.2 0.0 1.8e-48 164.6 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXH65091.1 - 1.2e-31 109.3 0.0 3.3e-31 107.9 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXH65091.1 - 0.0022 18.0 0.0 0.004 17.2 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 KXH65091.1 - 0.024 14.0 0.0 0.042 13.2 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit PTR2 PF00854.21 KXH65099.1 - 7.5e-56 189.7 6.2 7.8e-56 189.6 3.8 1.9 1 1 1 2 2 2 1 POT family p450 PF00067.22 KXH65101.1 - 6.4e-38 130.7 0.0 9e-38 130.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PV_NSP1 PF12433.8 KXH65101.1 - 0.057 13.8 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein 1 LAGLIDADG_2 PF03161.13 KXH65101.1 - 0.073 13.1 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 LAGLIDADG DNA endonuclease family Aldedh PF00171.22 KXH65102.1 - 3e-155 517.2 0.0 3.4e-155 517.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF4083 PF13314.6 KXH65103.1 - 0.093 12.7 0.0 0.25 11.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) Herpes_UL33 PF03581.13 KXH65103.1 - 0.16 12.4 0.0 0.42 11.0 0.0 1.7 1 0 0 1 1 1 0 Herpesvirus UL33-like protein MFS_1 PF07690.16 KXH65104.1 - 2.6e-32 112.1 52.8 3.5e-32 111.7 49.9 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily Methyltransf_22 PF13383.6 KXH65105.1 - 2.4e-14 53.5 0.3 3.4e-14 53.0 0.3 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.12 KXH65105.1 - 5.3e-09 36.3 0.0 7.5e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase FkbM domain SspK PF08176.12 KXH65106.1 - 0.019 15.2 0.5 8.6 6.7 0.1 2.4 2 0 0 2 2 2 0 Small acid-soluble spore protein K family Med19 PF10278.9 KXH65108.1 - 1.1 9.2 8.8 1.9 8.4 8.8 1.4 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Nucleo_P87 PF07267.11 KXH65108.1 - 1.6 7.5 7.7 2.7 6.7 7.7 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Presenilin PF01080.17 KXH65108.1 - 3.8 6.2 3.5 5 5.8 3.5 1.3 1 0 0 1 1 1 0 Presenilin FAD_binding_3 PF01494.19 KXH65109.1 - 2.2e-12 46.9 0.0 3.2e-11 43.1 0.0 2.3 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KXH65109.1 - 1.6e-08 34.1 0.0 0.001 18.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXH65109.1 - 5.8e-08 32.7 0.3 0.0011 18.6 0.2 2.3 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXH65109.1 - 1.3e-07 31.7 0.0 3.9e-07 30.2 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KXH65109.1 - 3.5e-05 23.1 0.2 7e-05 22.1 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 KXH65109.1 - 3.6e-05 23.2 0.1 0.00038 19.8 0.0 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXH65109.1 - 6.2e-05 21.9 0.1 0.003 16.3 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein Lycopene_cycl PF05834.12 KXH65109.1 - 0.00023 20.3 0.2 0.027 13.5 0.1 2.8 2 1 0 2 2 2 1 Lycopene cyclase protein GIDA PF01134.22 KXH65109.1 - 0.00059 19.0 0.1 0.058 12.5 0.0 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox PF00070.27 KXH65109.1 - 0.0017 18.9 0.1 0.034 14.7 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KXH65109.1 - 0.012 15.0 0.1 0.02 14.3 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 KXH65109.1 - 0.046 13.0 0.1 0.084 12.2 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GFO_IDH_MocA PF01408.22 KXH65111.1 - 6.2e-21 75.5 0.1 1.2e-20 74.5 0.1 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KXH65111.1 - 0.00016 21.7 0.0 0.00027 20.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain FRB_dom PF08771.11 KXH65111.1 - 0.16 12.4 0.0 0.3 11.5 0.0 1.4 1 0 0 1 1 1 0 FKBP12-rapamycin binding domain GFO_IDH_MocA PF01408.22 KXH65112.1 - 2e-14 54.4 0.0 3.4e-14 53.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold FAD_binding_3 PF01494.19 KXH65113.1 - 2.2e-10 40.4 0.0 6.9e-10 38.7 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KXH65113.1 - 0.0033 16.7 0.5 0.0072 15.6 0.5 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXH65113.1 - 0.0089 15.3 0.1 0.015 14.6 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXH65113.1 - 0.043 14.1 0.1 0.18 12.1 0.1 2.1 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Glyco_hydro_88 PF07470.13 KXH65113.1 - 0.075 12.1 0.1 0.11 11.6 0.1 1.2 1 0 0 1 1 1 0 Glycosyl Hydrolase Family 88 HI0933_like PF03486.14 KXH65113.1 - 0.081 11.6 0.2 0.16 10.7 0.2 1.5 1 0 0 1 1 1 0 HI0933-like protein Tannase PF07519.11 KXH65114.1 - 6.2e-109 365.0 0.1 7.4e-109 364.7 0.1 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_S9 PF00326.21 KXH65114.1 - 0.00032 20.2 0.1 0.65 9.4 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KXH65114.1 - 0.011 15.4 0.1 0.066 12.9 0.0 2.0 2 0 0 2 2 2 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXH65114.1 - 0.096 11.9 0.0 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Transp_cyt_pur PF02133.15 KXH65115.1 - 1.5e-35 122.8 30.6 1.4e-34 119.7 30.6 2.0 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin PIRT PF15099.6 KXH65115.1 - 0.22 11.1 1.1 1.4 8.5 0.2 2.6 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family PhyH PF05721.13 KXH65116.1 - 4.1e-19 69.7 0.0 5.3e-19 69.3 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_3 PF13640.6 KXH65116.1 - 0.0051 17.7 0.0 0.0097 16.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_5 PF13759.6 KXH65116.1 - 0.13 12.7 0.0 0.32 11.4 0.0 1.7 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase Asp_Arg_Hydrox PF05118.15 KXH65116.1 - 0.18 11.7 0.0 0.39 10.5 0.0 1.6 1 0 0 1 1 1 0 Aspartyl/Asparaginyl beta-hydroxylase SSF PF00474.17 KXH65119.1 - 5.8e-20 71.5 27.0 5.8e-20 71.5 27.0 1.8 2 0 0 2 2 2 1 Sodium:solute symporter family FAD_binding_3 PF01494.19 KXH65120.1 - 5.7e-81 272.5 0.0 7.1e-81 272.2 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 KXH65120.1 - 2.5e-41 141.5 0.0 2.8e-40 138.1 0.0 2.3 2 0 0 2 2 2 1 Phenol hydroxylase, C-terminal dimerisation domain FAD_binding_2 PF00890.24 KXH65120.1 - 0.00023 20.4 0.1 0.001 18.2 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain SE PF08491.10 KXH65120.1 - 0.00069 18.7 0.0 0.0016 17.5 0.0 1.6 1 1 0 1 1 1 1 Squalene epoxidase Thi4 PF01946.17 KXH65120.1 - 0.0015 17.9 0.0 0.0036 16.6 0.0 1.6 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 KXH65120.1 - 0.0028 17.1 0.2 0.0093 15.4 0.2 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 KXH65120.1 - 0.0058 16.3 0.6 0.042 13.4 0.1 2.2 1 1 1 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXH65120.1 - 0.019 14.2 0.1 0.062 12.5 0.1 1.8 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXH65120.1 - 0.069 13.4 0.1 0.18 12.1 0.1 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Polyketide_cyc2 PF10604.9 KXH65121.1 - 1.5e-07 31.7 0.2 1.7e-07 31.6 0.2 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport DUF4520 PF15016.6 KXH65121.1 - 0.021 14.9 0.0 0.044 13.9 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4520) adh_short PF00106.25 KXH65122.1 - 5.6e-35 120.6 0.0 1.2e-34 119.5 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXH65122.1 - 6e-17 62.0 0.0 1.2e-16 61.0 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase FMO-like PF00743.19 KXH65122.1 - 5.5e-10 38.3 0.0 1e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KXH65122.1 - 8e-10 38.4 0.4 3.4e-09 36.3 0.1 2.1 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KXH65122.1 - 5.1e-06 26.0 0.0 2.1e-05 23.9 0.0 2.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase KR PF08659.10 KXH65122.1 - 7.4e-06 26.0 0.0 3.7e-05 23.7 0.0 2.0 1 1 0 1 1 1 1 KR domain Pyr_redox_2 PF07992.14 KXH65122.1 - 0.0003 20.1 0.0 0.001 18.4 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 3Beta_HSD PF01073.19 KXH65122.1 - 0.0031 16.6 0.0 0.0051 15.9 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KXH65122.1 - 0.0044 16.5 0.0 0.0075 15.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 KXH65122.1 - 0.023 14.1 0.0 0.044 13.2 0.0 1.4 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) NAD_binding_8 PF13450.6 KXH65122.1 - 0.045 14.0 0.0 0.14 12.4 0.0 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Abhydrolase_3 PF07859.13 KXH65123.1 - 3.3e-21 76.1 0.0 4.5e-21 75.7 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KXH65123.1 - 1e-16 60.8 0.0 1.3e-16 60.4 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_2 PF02230.16 KXH65123.1 - 0.0085 15.9 0.1 0.59 9.9 0.0 2.9 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase Pes-10 PF07149.11 KXH65124.1 - 6.4 5.7 6.3 8.9 5.3 6.3 1.1 1 0 0 1 1 1 0 Pes-10 Amidohydro_2 PF04909.14 KXH65125.1 - 2.5e-22 80.0 0.0 3.1e-22 79.7 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase HET PF06985.11 KXH65126.1 - 9.5e-07 29.3 0.0 2.6e-06 27.9 0.0 1.8 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Glyco_hydro_10 PF00331.20 KXH65127.1 - 1.8e-100 336.2 0.8 2.1e-100 336.0 0.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Aldo_ket_red PF00248.21 KXH65128.1 - 4.5e-43 147.5 0.0 9.6e-43 146.5 0.0 1.5 1 1 0 1 1 1 1 Aldo/keto reductase family AA_permease_2 PF13520.6 KXH65129.1 - 1.1e-49 169.5 38.5 1.4e-49 169.1 38.5 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXH65129.1 - 6.7e-18 64.5 24.7 6.7e-18 64.5 24.7 2.2 2 0 0 2 2 2 2 Amino acid permease GAF PF01590.26 KXH65129.1 - 2.8e-09 37.7 0.0 8.9e-09 36.1 0.0 1.9 1 0 0 1 1 1 1 GAF domain PHY PF00360.20 KXH65129.1 - 3.1e-05 23.4 0.0 6.5e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Phytochrome region RNF220 PF15926.5 KXH65131.1 - 0.3 10.7 0.7 0.53 9.9 0.7 1.3 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase RNF220 zf-MYND PF01753.18 KXH65132.1 - 0.00044 20.3 10.0 0.00044 20.3 10.0 2.1 2 0 0 2 2 2 1 MYND finger PolC_DP2 PF03833.13 KXH65132.1 - 0.003 15.5 4.7 0.0034 15.3 4.7 1.0 1 0 0 1 1 1 1 DNA polymerase II large subunit DP2 SAUGI PF06106.11 KXH65132.1 - 0.059 13.9 0.0 0.088 13.3 0.0 1.2 1 0 0 1 1 1 0 S. aureus uracil DNA glycosylase inhibitor zf-HIT PF04438.16 KXH65132.1 - 2.8 7.9 10.6 33 4.5 0.0 2.6 2 0 0 2 2 2 0 HIT zinc finger Mitofilin PF09731.9 KXH65135.1 - 5.4 5.7 8.7 6.8 5.4 8.7 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF1664 PF07889.12 KXH65154.1 - 8.5e-05 22.6 0.8 0.00013 22.0 0.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) WEMBL PF05701.11 KXH65154.1 - 0.0005 18.9 0.5 0.00068 18.5 0.5 1.1 1 0 0 1 1 1 1 Weak chloroplast movement under blue light LPP PF04728.13 KXH65154.1 - 0.00073 19.9 3.9 0.019 15.3 0.2 2.0 1 1 2 3 3 3 3 Lipoprotein leucine-zipper EzrA PF06160.12 KXH65154.1 - 0.0025 16.1 0.3 0.0035 15.6 0.3 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA DUF3584 PF12128.8 KXH65154.1 - 0.0029 15.2 0.9 0.0039 14.8 0.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Baculo_PEP_C PF04513.12 KXH65154.1 - 0.0033 17.5 0.3 0.0053 16.8 0.3 1.2 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus CCDC154 PF15450.6 KXH65154.1 - 0.0037 15.9 1.5 0.0052 15.4 1.5 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 154 NPV_P10 PF05531.12 KXH65154.1 - 0.0069 16.8 3.5 0.022 15.2 3.6 1.8 1 1 0 1 1 1 1 Nucleopolyhedrovirus P10 protein DUF2353 PF09789.9 KXH65154.1 - 0.014 14.8 2.8 0.023 14.1 2.8 1.3 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) Golgin_A5 PF09787.9 KXH65154.1 - 0.02 14.3 0.3 0.029 13.9 0.3 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 CreD PF06123.12 KXH65154.1 - 0.031 13.1 0.0 0.044 12.6 0.0 1.1 1 0 0 1 1 1 0 Inner membrane protein CreD DivIC PF04977.15 KXH65154.1 - 0.033 14.0 0.1 0.087 12.6 0.1 1.8 1 0 0 1 1 1 0 Septum formation initiator COG7 PF10191.9 KXH65154.1 - 0.033 12.4 0.2 0.044 12.0 0.2 1.1 1 0 0 1 1 1 0 Golgi complex component 7 (COG7) DUF848 PF05852.11 KXH65154.1 - 0.034 14.3 0.8 0.058 13.5 0.8 1.3 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) NleF_casp_inhib PF16809.5 KXH65154.1 - 0.034 14.1 0.1 0.11 12.4 0.1 1.8 1 1 0 1 1 1 0 NleF caspase inhibitor DUF4988 PF16378.5 KXH65154.1 - 0.034 13.8 0.1 0.058 13.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function MAD PF05557.13 KXH65154.1 - 0.035 12.5 0.1 0.049 12.0 0.1 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein CdvA PF18822.1 KXH65154.1 - 0.037 13.8 0.8 0.28 11.0 0.3 2.1 1 1 1 2 2 2 0 CdvA-like coiled-coil domain Lectin_N PF03954.14 KXH65154.1 - 0.042 13.6 0.7 0.55 10.0 0.1 2.1 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain Filament PF00038.21 KXH65154.1 - 0.048 13.2 0.8 0.069 12.7 0.8 1.2 1 0 0 1 1 1 0 Intermediate filament protein Fez1 PF06818.15 KXH65154.1 - 0.053 14.0 0.0 0.083 13.3 0.0 1.3 1 0 0 1 1 1 0 Fez1 zf-C4H2 PF10146.9 KXH65154.1 - 0.06 13.6 0.1 0.1 12.9 0.1 1.3 1 1 0 1 1 1 0 Zinc finger-containing protein Fzo_mitofusin PF04799.13 KXH65154.1 - 0.067 12.7 0.4 0.19 11.2 0.1 1.7 1 1 1 2 2 2 0 fzo-like conserved region Halo_GVPC PF05465.13 KXH65154.1 - 0.069 13.4 1.1 5.9 7.3 0.2 2.6 2 0 0 2 2 2 0 Halobacterial gas vesicle protein C (GVPC) repeat TPR_MLP1_2 PF07926.12 KXH65154.1 - 0.069 13.2 0.2 0.34 11.0 0.1 1.9 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 KXH65154.1 - 0.07 12.0 0.9 0.11 11.4 0.9 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Seryl_tRNA_N PF02403.22 KXH65154.1 - 0.076 13.2 1.3 0.24 11.7 0.2 2.1 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain CALCOCO1 PF07888.11 KXH65154.1 - 0.11 11.4 1.2 0.15 10.9 1.2 1.2 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF4140 PF13600.6 KXH65154.1 - 0.14 12.6 0.4 0.3 11.6 0.4 1.6 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) YabA PF06156.13 KXH65154.1 - 0.15 12.7 0.3 0.28 11.9 0.3 1.4 1 0 0 1 1 1 0 Initiation control protein YabA DUF2730 PF10805.8 KXH65154.1 - 0.16 12.1 0.9 1.3 9.2 0.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) Type2_restr_D3 PF16902.5 KXH65154.1 - 0.2 11.6 3.0 1.9 8.5 0.5 2.4 1 1 1 2 2 2 0 Type-2 restriction enzyme D3 domain betaPIX_CC PF16523.5 KXH65154.1 - 0.21 11.4 2.1 2.6 7.9 2.1 2.4 1 1 0 1 1 1 0 betaPIX coiled coil Atg14 PF10186.9 KXH65154.1 - 0.22 10.6 0.8 0.31 10.1 0.8 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF2746 PF10874.8 KXH65154.1 - 1.3 9.5 3.5 3.2 8.2 2.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2746) zf-Nse PF11789.8 KXH65170.1 - 7.8e-20 70.5 0.1 3.2e-19 68.5 0.1 2.0 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 KXH65170.1 - 7.5e-06 25.9 0.2 1.6e-05 24.8 0.2 1.6 1 0 0 1 1 1 1 RING-type zinc-finger U-box PF04564.15 KXH65170.1 - 0.00024 21.2 0.0 0.0007 19.7 0.0 1.6 1 1 0 1 1 1 1 U-box domain zf-C3HC4_2 PF13923.6 KXH65170.1 - 0.00061 19.6 0.1 0.0012 18.6 0.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KXH65170.1 - 0.019 15.2 0.0 0.043 14.1 0.0 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 KXH65170.1 - 0.025 14.8 0.1 0.078 13.1 0.0 1.8 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-MIZ PF02891.20 KXH65170.1 - 0.27 11.0 1.4 0.31 10.8 0.3 1.7 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger tRNA_bind_2 PF13725.6 KXH65170.1 - 2.6 7.7 6.1 0.55 9.9 1.4 2.0 2 0 0 2 2 2 0 Possible tRNA binding domain Hexokinase_2 PF03727.16 KXH65171.1 - 5e-54 183.3 0.0 8.3e-54 182.5 0.0 1.4 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 KXH65171.1 - 4.3e-38 131.2 0.0 7.2e-38 130.5 0.0 1.3 1 0 0 1 1 1 1 Hexokinase dbPDZ_assoc PF16610.5 KXH65171.1 - 0.22 11.8 2.5 5.6 7.3 0.1 2.6 2 0 0 2 2 2 0 Unstructured region between two PDZ domains on Dlg5 Glucosamine_iso PF01182.20 KXH65172.1 - 2.7e-20 73.2 0.0 4.6e-20 72.5 0.0 1.3 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase DUF3464 PF11947.8 KXH65172.1 - 0.04 13.7 2.5 1.5 8.6 0.2 2.3 1 1 1 2 2 2 0 Photosynthesis affected mutant 68 NDT80_PhoG PF05224.12 KXH65173.1 - 3.3e-33 115.5 0.0 5.9e-33 114.6 0.0 1.4 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family Amidohydro_1 PF01979.20 KXH65174.1 - 2.6e-16 59.9 0.2 4e-16 59.3 0.2 1.3 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KXH65174.1 - 5.3e-10 39.4 0.5 1.6e-08 34.5 0.1 2.8 3 0 0 3 3 3 1 Amidohydrolase family Glyco_hydro_3 PF00933.21 KXH65175.1 - 1.2e-63 215.5 0.0 1.7e-63 214.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 KXH65175.1 - 0.0023 17.9 0.0 0.0044 17.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Acetyltransf_1 PF00583.25 KXH65175.1 - 0.055 13.7 0.0 0.19 11.9 0.0 1.9 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Glyco_hydro_31 PF01055.26 KXH65176.1 - 4.2e-111 372.3 0.7 5.1e-111 372.0 0.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 KXH65176.1 - 8.4e-14 51.6 0.2 7.2e-13 48.7 0.1 2.5 2 0 0 2 2 2 1 Galactose mutarotase-like Glyco_hydro_3 PF00933.21 KXH65177.1 - 2.1e-59 201.5 0.0 3.2e-59 200.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 KXH65177.1 - 1.5e-52 178.5 0.1 2.3e-52 177.9 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 KXH65177.1 - 4.8e-23 81.0 0.3 1.1e-22 79.9 0.3 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF11 PF01345.18 KXH65177.1 - 0.0083 16.4 0.1 0.026 14.8 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function DUF11 Sugar-bind PF04198.13 KXH65177.1 - 0.14 11.2 0.0 0.27 10.3 0.0 1.3 1 0 0 1 1 1 0 Putative sugar-binding domain RINGv PF12906.7 KXH65183.1 - 0.00013 22.0 7.0 0.00022 21.3 7.0 1.4 1 0 0 1 1 1 1 RING-variant domain FANCL_C PF11793.8 KXH65183.1 - 0.00027 21.0 3.0 0.00051 20.2 3.0 1.5 1 0 0 1 1 1 1 FANCL C-terminal domain zf-RING_2 PF13639.6 KXH65183.1 - 0.00098 19.4 5.9 0.0016 18.7 5.9 1.4 1 0 0 1 1 1 1 Ring finger domain Band_7 PF01145.25 KXH65184.1 - 9.7e-28 97.4 2.7 1.4e-27 96.8 2.7 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 KXH65184.1 - 0.014 15.1 0.2 0.022 14.5 0.2 1.3 1 0 0 1 1 1 0 SPFH domain-Band 7 family DUF1788 PF08747.11 KXH65184.1 - 0.094 12.7 0.1 0.55 10.2 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1788) TT_ORF2 PF02957.15 KXH65186.1 - 9.3 7.2 12.4 2.8 8.9 3.5 2.4 2 0 0 2 2 2 0 TT viral ORF2 KxDL PF10241.9 KXH65187.1 - 1.9e-30 105.0 2.3 2.7e-30 104.5 2.3 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein DUF2385 PF09539.10 KXH65187.1 - 0.0045 17.5 0.6 0.012 16.1 0.6 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2385) Herpes_capsid PF06112.11 KXH65187.1 - 0.28 11.2 8.0 0.51 10.4 8.0 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein XylR_N PF06505.11 KXH65187.1 - 0.34 10.7 1.1 0.46 10.3 0.1 1.7 2 0 0 2 2 2 0 Activator of aromatic catabolism DUF883 PF05957.13 KXH65187.1 - 0.89 10.2 5.8 5.7 7.6 1.6 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) DEAD PF00270.29 KXH65189.1 - 2.9e-37 128.1 0.0 7.1e-37 126.9 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXH65189.1 - 1.4e-23 83.4 0.0 4.1e-23 81.9 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KXH65189.1 - 2e-20 72.8 0.0 3.3e-20 72.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KXH65189.1 - 0.0027 17.7 0.0 0.0088 16.1 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SprA-related PF12118.8 KXH65189.1 - 6.1 5.9 11.2 9.2 5.3 11.2 1.1 1 0 0 1 1 1 0 SprA-related family Ank_2 PF12796.7 KXH65190.1 - 1e-33 115.7 5.5 9.4e-12 45.4 0.3 7.0 4 3 1 6 6 6 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXH65190.1 - 2.8e-30 104.3 8.3 3.8e-07 30.5 0.0 8.3 5 2 5 10 10 10 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXH65190.1 - 8e-28 93.4 9.1 0.00035 20.8 0.0 10.0 9 0 0 9 9 9 7 Ankyrin repeat Ank_5 PF13857.6 KXH65190.1 - 5.4e-20 71.2 8.8 0.00068 19.9 0.2 8.5 5 2 4 9 9 9 5 Ankyrin repeats (many copies) Ank PF00023.30 KXH65190.1 - 3.3e-14 52.6 18.8 0.012 16.0 0.4 8.8 9 0 0 9 9 9 5 Ankyrin repeat Clr5 PF14420.6 KXH65190.1 - 5.5e-10 39.3 0.0 2.9e-09 37.0 0.1 2.2 2 0 0 2 2 2 1 Clr5 domain RasGEF PF00617.19 KXH65191.1 - 6.7e-48 163.2 0.5 1.1e-47 162.6 0.5 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KXH65191.1 - 5.1e-11 42.8 0.0 1.1e-10 41.7 0.0 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif Ribosomal_S2 PF00318.20 KXH65192.1 - 5.6e-27 94.4 0.1 4.5e-15 55.5 0.1 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 KXH65192.1 - 6.2e-07 30.7 11.9 1.1e-06 29.9 11.9 1.4 1 0 0 1 1 1 1 40S ribosomal protein SA C-terminus Ribosomal_S15 PF00312.22 KXH65193.1 - 1.8e-22 79.3 1.0 7e-22 77.4 0.4 2.1 2 0 0 2 2 2 1 Ribosomal protein S15 vATP-synt_AC39 PF01992.16 KXH65194.1 - 2.6e-108 362.5 0.0 2.9e-108 362.4 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Nop PF01798.18 KXH65195.1 - 1.5e-76 256.9 0.0 1.5e-76 256.9 0.0 2.3 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 KXH65195.1 - 3.9e-18 65.6 0.5 3.9e-18 65.6 0.5 3.3 3 0 0 3 3 3 1 NOP5NT (NUC127) domain GARS_A PF01071.19 KXH65197.1 - 2.1e-73 246.3 0.0 3.1e-73 245.7 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ANAPC10 PF03256.16 KXH65197.1 - 1.2e-47 161.9 0.0 2.2e-47 161.1 0.0 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) HET PF06985.11 KXH65197.1 - 1.1e-31 110.2 0.0 1.8e-31 109.5 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) GARS_N PF02844.15 KXH65197.1 - 4e-30 104.5 0.0 8e-30 103.5 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.16 KXH65197.1 - 6.5e-23 80.8 0.1 2.7e-22 78.9 0.1 2.2 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, C domain ATP-grasp_3 PF02655.14 KXH65197.1 - 0.0091 16.1 0.0 0.065 13.3 0.0 2.2 2 0 0 2 2 2 1 ATP-grasp domain CPSase_L_D2 PF02786.17 KXH65197.1 - 0.18 11.3 0.2 0.4 10.1 0.0 1.7 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, ATP binding domain NAD_binding_10 PF13460.6 KXH65198.1 - 7.9e-11 42.2 0.0 1.9e-10 40.9 0.0 1.6 2 0 0 2 2 2 1 NAD(P)H-binding MFS_1 PF07690.16 KXH65199.1 - 2.2e-26 92.6 50.7 4.5e-17 62.0 31.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KXH65199.1 - 0.0034 16.3 20.3 0.0054 15.6 7.9 2.6 1 1 0 2 2 2 2 MFS_1 like family DUF5597 PF18120.1 KXH65200.1 - 2.7e-26 92.3 0.0 4.1e-26 91.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5597) Glyco_hydro_42 PF02449.15 KXH65200.1 - 2.3e-12 47.0 0.0 3.7e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 Beta-galactosidase Glyco_hydro_35 PF01301.19 KXH65200.1 - 1.7e-07 31.1 0.0 3.2e-06 27.0 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 35 Fungal_trans PF04082.18 KXH65201.1 - 2.1e-10 40.1 2.2 4e-10 39.2 2.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans_2 PF11951.8 KXH65201.1 - 0.0014 17.5 0.3 0.002 17.0 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sugar_tr PF00083.24 KXH65202.1 - 1.6e-85 287.6 24.8 1.8e-85 287.5 24.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH65202.1 - 3.7e-20 72.1 39.7 2.5e-16 59.6 11.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PTR2 PF00854.21 KXH65202.1 - 0.097 11.5 14.1 0.21 10.4 4.2 2.3 2 0 0 2 2 2 0 POT family F-box PF00646.33 KXH65203.1 - 2.8e-05 23.9 0.0 5.5e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KXH65203.1 - 7e-05 22.6 0.0 0.00015 21.5 0.0 1.6 1 0 0 1 1 1 1 F-box-like PHD_Oberon PF07227.11 KXH65203.1 - 0.037 13.9 0.2 0.065 13.1 0.2 1.3 1 0 0 1 1 1 0 PHD - plant homeodomain finger protein PRANC PF09372.10 KXH65203.1 - 0.17 12.3 0.0 0.34 11.3 0.0 1.4 1 0 0 1 1 1 0 PRANC domain DUF2177 PF09945.9 KXH65203.1 - 0.24 11.5 6.4 0.82 9.8 0.2 2.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2177) DUF2070 PF09843.9 KXH65203.1 - 3.1 6.0 6.0 4.3 5.5 6.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Actin PF00022.19 KXH65204.1 - 9.3e-65 218.8 0.0 1.4e-62 211.6 0.0 2.0 1 1 0 1 1 1 1 Actin Histone PF00125.24 KXH65205.1 - 1.6e-17 64.1 0.0 2.1e-17 63.7 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 KXH65205.1 - 1.1e-12 47.4 0.8 1.9e-12 46.7 0.1 1.8 2 0 0 2 2 2 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 KXH65205.1 - 6.3e-05 23.2 0.0 9.7e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone HET PF06985.11 KXH65208.1 - 2.7e-30 105.7 2.0 3.9e-30 105.1 2.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ZZ PF00569.17 KXH65208.1 - 2.3e-05 24.1 4.7 6.5e-05 22.7 4.7 1.7 1 0 0 1 1 1 1 Zinc finger, ZZ type C1_2 PF03107.16 KXH65208.1 - 0.00049 20.4 10.6 0.0014 18.9 10.6 1.8 1 1 0 1 1 1 1 C1 domain AA_permease PF00324.21 KXH65209.1 - 9.9e-146 486.1 37.8 1.3e-145 485.7 37.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KXH65209.1 - 1.1e-39 136.5 43.6 2e-39 135.6 43.6 1.4 1 0 0 1 1 1 1 Amino acid permease Tri3 PF07428.11 KXH65210.1 - 0.0003 19.8 0.4 0.00095 18.2 0.4 1.7 1 1 0 1 1 1 1 15-O-acetyltransferase Tri3 MCR_beta_N PF02783.15 KXH65212.1 - 0.085 12.5 0.0 0.099 12.3 0.0 1.1 1 0 0 1 1 1 0 Methyl-coenzyme M reductase beta subunit, N-terminal domain RAG2 PF03089.14 KXH65212.1 - 0.089 11.8 0.0 0.1 11.6 0.0 1.0 1 0 0 1 1 1 0 Recombination activating protein 2 F-box-like PF12937.7 KXH65214.1 - 6.1e-11 42.0 4.1 6.2e-11 42.0 0.1 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KXH65214.1 - 1e-07 31.6 0.6 2.2e-07 30.6 0.0 1.8 2 0 0 2 2 2 1 F-box domain LRR_4 PF12799.7 KXH65214.1 - 0.00066 20.0 2.1 2 9.0 0.6 3.6 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) TPR_1 PF00515.28 KXH65214.1 - 0.0025 17.5 0.5 1.7 8.6 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 KXH65214.1 - 0.058 13.5 6.2 3.7 7.9 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KXH65214.1 - 0.15 13.0 0.6 0.68 10.9 0.6 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat ADIP PF11559.8 KXH65215.1 - 1.6e-40 138.7 3.9 4.6e-40 137.2 3.9 1.9 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding DUF4686 PF15742.5 KXH65215.1 - 0.0012 18.0 1.0 0.0028 16.9 1.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4686) Golgin_A5 PF09787.9 KXH65215.1 - 0.0041 16.6 2.8 0.015 14.8 2.8 1.9 1 0 0 1 1 1 1 Golgin subfamily A member 5 DUF641 PF04859.12 KXH65215.1 - 0.13 12.6 5.1 1.2 9.5 1.2 3.0 2 1 1 3 3 3 0 Plant protein of unknown function (DUF641) Phage_GP20 PF06810.11 KXH65215.1 - 0.2 11.5 2.1 3 7.6 0.7 2.4 1 1 1 2 2 2 0 Phage minor structural protein GP20 Macoilin PF09726.9 KXH65215.1 - 0.32 9.5 8.4 0.025 13.2 2.0 2.0 2 0 0 2 2 2 0 Macoilin family DegS PF05384.11 KXH65215.1 - 0.45 10.0 6.0 1.3 8.5 6.0 1.7 1 0 0 1 1 1 0 Sensor protein DegS Spc7 PF08317.11 KXH65215.1 - 1.3 7.8 7.3 0.8 8.5 5.2 1.7 2 0 0 2 2 2 0 Spc7 kinetochore protein Fez1 PF06818.15 KXH65215.1 - 3.6 8.0 13.2 0.46 10.9 4.9 2.7 1 1 1 2 2 2 0 Fez1 TPR_MLP1_2 PF07926.12 KXH65215.1 - 3.9 7.6 11.5 3.4 7.7 5.6 3.2 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein AdoMet_MTase PF07757.13 KXH65216.1 - 3.2e-39 133.7 0.0 5e-39 133.1 0.0 1.3 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_23 PF13489.6 KXH65216.1 - 0.036 13.9 0.0 0.078 12.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.6 KXH65216.1 - 0.072 13.1 0.0 1.9 8.5 0.0 2.4 3 0 0 3 3 3 0 Methyltransferase domain NMO PF03060.15 KXH65217.1 - 1.3e-32 113.5 12.2 4.1e-32 111.9 12.2 1.7 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KXH65217.1 - 1.3e-13 50.7 5.0 1.9e-13 50.1 5.0 1.2 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KXH65217.1 - 1.9e-06 27.1 9.7 3e-06 26.5 9.7 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 KXH65217.1 - 0.00025 20.3 3.9 0.00037 19.7 3.9 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase Aldo_ket_red PF00248.21 KXH65218.1 - 1.1e-69 234.9 0.0 1.2e-69 234.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family IDEAL PF08858.10 KXH65218.1 - 0.033 13.9 0.8 0.079 12.7 0.8 1.6 1 0 0 1 1 1 0 IDEAL domain FliG_M PF14841.6 KXH65218.1 - 0.11 12.7 0.2 0.18 12.1 0.2 1.3 1 0 0 1 1 1 0 FliG middle domain CedA PF10729.9 KXH65218.1 - 0.11 12.3 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 Cell division activator CedA NAT PF04768.13 KXH65219.1 - 8.5e-50 168.7 0.0 3.4e-49 166.8 0.0 1.8 2 0 0 2 2 2 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase NAD_binding_2 PF03446.15 KXH65220.1 - 3.9e-27 95.4 0.1 6.1e-27 94.7 0.1 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KXH65220.1 - 1.3e-12 48.0 0.3 1.1e-10 41.8 0.0 2.2 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Shikimate_DH PF01488.20 KXH65220.1 - 2.9e-09 37.1 0.0 1.2e-08 35.1 0.0 1.9 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 KXH65220.1 - 8.4e-09 35.9 0.0 2.1e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 KXH65220.1 - 0.00018 21.8 0.1 0.00046 20.4 0.1 1.8 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_3 PF03447.16 KXH65220.1 - 0.0014 19.2 0.1 0.0036 18.0 0.1 1.7 1 1 1 2 2 2 1 Homoserine dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 KXH65220.1 - 0.0023 17.3 0.0 0.0034 16.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 KXH65220.1 - 0.016 15.5 0.2 0.053 13.8 0.2 1.9 1 1 0 1 1 1 0 TrkA-N domain KR PF08659.10 KXH65220.1 - 0.028 14.3 0.2 0.24 11.3 0.0 2.3 2 1 1 3 3 3 0 KR domain HTH_Tnp_Mu_2 PF09039.11 KXH65220.1 - 0.03 14.4 0.0 0.13 12.4 0.0 1.9 2 0 0 2 2 2 0 Mu DNA binding, I gamma subdomain UDPG_MGDP_dh_N PF03721.14 KXH65220.1 - 0.045 13.3 0.2 0.25 10.9 0.1 2.3 2 1 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain GFO_IDH_MocA PF01408.22 KXH65220.1 - 0.073 13.9 0.0 0.17 12.7 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.24 KXH65220.1 - 0.08 13.4 0.0 0.21 12.0 0.0 1.7 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain ATP_synt_H PF05493.13 KXH65221.1 - 8.3e-24 83.8 1.8 9.5e-24 83.6 1.8 1.0 1 0 0 1 1 1 1 ATP synthase subunit H DUF4131 PF13567.6 KXH65221.1 - 0.034 13.8 1.3 0.036 13.7 1.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Flavi_NS4A PF01350.17 KXH65221.1 - 0.038 13.9 0.6 0.044 13.7 0.6 1.1 1 0 0 1 1 1 0 Flavivirus non-structural protein NS4A PsbX PF06596.11 KXH65221.1 - 0.076 13.0 0.6 0.16 12.0 0.6 1.5 1 0 0 1 1 1 0 Photosystem II reaction centre X protein (PsbX) ARL6IP6 PF15062.6 KXH65221.1 - 0.13 12.4 0.1 0.17 12.0 0.1 1.4 1 1 0 1 1 1 0 Haemopoietic lineage transmembrane helix DUF2070 PF09843.9 KXH65221.1 - 0.14 10.4 0.1 0.15 10.3 0.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Arv1 PF04161.13 KXH65222.1 - 2.6e-79 266.2 0.7 3.2e-79 266.0 0.7 1.1 1 0 0 1 1 1 1 Arv1-like family LysM PF01476.20 KXH65223.1 - 0.025 14.6 0.0 0.045 13.8 0.0 1.5 1 0 0 1 1 1 0 LysM domain Fungal_trans PF04082.18 KXH65224.1 - 2.6e-38 131.6 0.0 4.4e-38 130.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Lipocalin_9 PF17186.4 KXH65226.1 - 6.6e-09 36.1 0.2 3.1e-08 34.0 0.1 2.0 2 0 0 2 2 2 1 Lipocalin-like domain CrtC PF07143.11 KXH65226.1 - 1.5e-05 25.8 0.2 2.6e-05 24.9 0.2 1.5 1 0 0 1 1 1 1 CrtC N-terminal lipocalin domain RTA1 PF04479.13 KXH65227.1 - 4.6e-65 219.1 8.4 6.7e-65 218.6 8.4 1.2 1 0 0 1 1 1 1 RTA1 like protein DUF3176 PF11374.8 KXH65228.1 - 2.6e-36 124.0 0.3 3.3e-35 120.5 0.3 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) Zn_clus PF00172.18 KXH65229.1 - 7.5e-10 38.8 8.5 1.4e-09 37.9 8.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Corazonin PF17308.2 KXH65229.1 - 0.039 14.3 0.4 0.055 13.8 0.4 1.2 1 0 0 1 1 1 0 Pro-corazonin EndIII_4Fe-2S PF10576.9 KXH65229.1 - 1.7 9.1 9.2 5 7.6 1.0 2.9 2 0 0 2 2 2 0 Iron-sulfur binding domain of endonuclease III Croc_4 PF17691.1 KXH65230.1 - 0.021 14.9 0.0 0.041 13.9 0.0 1.5 1 0 0 1 1 1 0 Contingent replication of cDNA 4 Lipase_GDSL PF00657.22 KXH65231.1 - 1.6e-07 31.5 0.0 2.2e-07 31.0 0.0 1.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 KXH65231.1 - 0.0026 18.2 5.9 0.0044 17.4 5.9 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Homeobox_KN PF05920.11 KXH65234.1 - 3.8e-22 77.9 0.6 8.3e-22 76.8 0.6 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 KXH65234.1 - 9.8e-09 34.9 1.4 2.6e-08 33.6 1.4 1.7 1 0 0 1 1 1 1 Homeodomain Fungal_trans PF04082.18 KXH65236.1 - 1.3e-13 50.6 2.0 3.5e-13 49.2 0.3 2.5 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH65236.1 - 9e-10 38.5 10.9 1.6e-09 37.7 10.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Bac_export_2 PF01312.19 KXH65238.1 - 0.15 11.2 0.8 0.27 10.4 0.3 1.4 1 1 0 1 1 1 0 FlhB HrpN YscU SpaS Family DUF4118 PF13493.6 KXH65238.1 - 0.86 9.4 12.5 0.02 14.7 3.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4118) DUF5527 PF17665.1 KXH65238.1 - 6.9 6.2 5.3 1.2 8.7 0.2 2.3 2 1 1 3 3 3 0 Family of unknown function (DUF5527) GMC_oxred_N PF00732.19 KXH65239.1 - 3e-59 200.8 0.0 4.1e-59 200.4 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXH65239.1 - 6.3e-38 130.5 0.0 1.2e-37 129.6 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KXH65239.1 - 0.0013 18.9 0.1 0.0032 17.7 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXH65239.1 - 0.002 17.4 0.3 0.86 8.8 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXH65239.1 - 0.024 14.2 0.1 0.18 11.4 0.1 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KXH65239.1 - 0.038 13.0 0.3 0.068 12.2 0.3 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein AIG2_2 PF13772.6 KXH65240.1 - 3e-07 30.7 0.0 3.7e-06 27.2 0.0 2.2 1 1 0 1 1 1 1 AIG2-like family GGACT PF06094.12 KXH65240.1 - 7.2e-07 29.8 0.0 1.1e-06 29.3 0.0 1.3 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like Asp PF00026.23 KXH65241.1 - 8.9e-73 245.4 6.0 1.1e-72 245.2 6.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KXH65241.1 - 2.4e-13 50.7 4.9 1.8e-11 44.6 3.8 3.5 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KXH65241.1 - 2.3e-06 28.1 1.7 0.021 15.4 0.3 3.8 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.6 KXH65241.1 - 0.0052 16.6 0.0 0.03 14.1 0.0 2.1 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal ATP-synt_C PF00137.21 KXH65242.1 - 8.7e-30 102.9 25.8 1.9e-21 76.1 10.5 2.1 2 0 0 2 2 2 2 ATP synthase subunit C SH PF01445.17 KXH65242.1 - 2.9 7.9 5.5 1.8 8.6 0.8 2.4 3 0 0 3 3 3 0 Viral small hydrophobic protein SLATT_5 PF18160.1 KXH65242.1 - 7.3 5.9 7.0 4.7 6.5 0.8 2.4 2 1 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 Pep3_Vps18 PF05131.14 KXH65243.1 - 6.2e-48 162.4 0.0 1.5e-47 161.2 0.0 1.7 1 0 0 1 1 1 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 KXH65243.1 - 9.2e-11 41.8 2.8 5.8e-09 36.0 0.1 3.2 3 0 0 3 3 3 1 Region in Clathrin and VPS zf-C3HC4_2 PF13923.6 KXH65243.1 - 0.00043 20.1 0.5 0.00089 19.1 0.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF2175 PF09943.9 KXH65243.1 - 0.00058 20.1 0.0 0.002 18.4 0.0 1.9 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2175) zf-RING_5 PF14634.6 KXH65243.1 - 0.0012 18.8 0.4 0.0012 18.8 0.4 1.6 2 0 0 2 2 1 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 KXH65243.1 - 0.0019 17.8 0.1 0.0037 16.9 0.1 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_2 PF13639.6 KXH65243.1 - 0.0038 17.5 0.5 0.0091 16.3 0.5 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KXH65243.1 - 0.015 15.3 0.5 0.035 14.1 0.5 1.6 1 0 0 1 1 1 0 RING-type zinc-finger Vps39_2 PF10367.9 KXH65243.1 - 0.064 13.7 0.0 0.19 12.2 0.0 1.9 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 zf-C3HC4 PF00097.25 KXH65243.1 - 0.1 12.5 0.2 0.27 11.1 0.2 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) UCH PF00443.29 KXH65243.1 - 0.18 11.3 0.1 0.28 10.7 0.1 1.3 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase zf-rbx1 PF12678.7 KXH65243.1 - 0.19 12.0 0.2 0.44 10.9 0.2 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3H2C3 PF17122.5 KXH65243.1 - 0.36 10.9 6.8 0.053 13.6 2.5 1.8 2 0 0 2 2 2 0 Zinc-finger zf-RING_11 PF17123.5 KXH65243.1 - 1.7 8.5 11.5 0.054 13.2 4.3 2.1 2 0 0 2 2 2 0 RING-like zinc finger Methyltransf_23 PF13489.6 KXH65244.1 - 2.5e-14 53.4 0.0 4.5e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH65244.1 - 2.4e-10 41.0 0.0 7.5e-10 39.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH65244.1 - 9.5e-08 32.7 0.0 2.6e-07 31.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH65244.1 - 2.8e-07 30.5 0.0 2.2e-06 27.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH65244.1 - 5.6e-07 30.1 0.0 1.6e-06 28.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXH65244.1 - 5.8e-05 22.5 0.0 0.00043 19.7 0.0 2.2 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 KXH65244.1 - 0.0021 17.6 0.0 0.0036 16.8 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.14 KXH65244.1 - 0.0032 17.0 0.0 0.0068 16.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.18 KXH65244.1 - 0.0054 16.0 0.0 0.017 14.4 0.0 1.9 2 0 0 2 2 2 1 O-methyltransferase domain Terminase_1 PF03354.15 KXH65244.1 - 0.044 12.3 0.0 0.062 11.8 0.0 1.1 1 0 0 1 1 1 0 Phage Terminase DUF938 PF06080.12 KXH65244.1 - 0.15 11.8 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) FMO-like PF00743.19 KXH65275.1 - 7.6e-14 51.0 0.0 4.9e-11 41.7 0.0 3.0 3 0 0 3 3 3 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KXH65275.1 - 3.9e-12 46.0 0.0 2.1e-10 40.3 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXH65275.1 - 8.5e-11 41.6 0.0 1e-09 38.1 0.0 2.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXH65275.1 - 1.9e-10 40.8 0.0 5.5e-08 32.9 0.0 3.0 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KXH65275.1 - 1.4e-07 31.0 0.0 0.00076 18.7 0.0 3.7 4 0 0 4 4 4 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 KXH65275.1 - 0.0002 21.8 0.1 0.13 12.9 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXH65275.1 - 0.00046 19.5 2.4 0.025 13.8 0.0 3.9 5 0 0 5 5 5 1 Thi4 family 2-Hacid_dh_C PF02826.19 KXH65275.1 - 0.0044 16.4 0.0 0.0084 15.5 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DAO PF01266.24 KXH65275.1 - 0.0047 16.6 0.0 0.044 13.4 0.0 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KXH65275.1 - 0.009 16.0 0.5 12 5.8 0.0 4.2 5 0 0 5 5 5 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 KXH65275.1 - 0.01 15.0 0.0 0.018 14.2 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 KXH65275.1 - 0.094 11.4 0.3 0.23 10.1 0.1 1.7 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_7 PF13241.6 KXH65275.1 - 0.17 12.3 0.0 0.55 10.7 0.0 1.9 1 0 0 1 1 1 0 Putative NAD(P)-binding Chromo PF00385.24 KXH65279.1 - 3.4e-05 23.7 0.1 9.4e-05 22.2 0.1 1.8 1 1 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain UL42 PF17638.2 KXH65280.1 - 0.26 11.3 4.7 0.41 10.6 4.7 1.3 1 0 0 1 1 1 0 HCMV UL42 Fumble PF03630.14 KXH65281.1 - 4e-145 483.1 0.0 5e-145 482.8 0.0 1.1 1 0 0 1 1 1 1 Fumble Gag_p12 PF01141.18 KXH65282.1 - 0.083 13.2 0.4 0.12 12.8 0.4 1.2 1 0 0 1 1 1 0 Gag polyprotein, inner coat protein p12 PAN_3 PF08277.12 KXH65282.1 - 0.15 11.9 4.0 0.21 11.4 4.0 1.3 1 0 0 1 1 1 0 PAN-like domain NLE PF08154.12 KXH65283.1 - 1.9e-15 57.1 0.7 3.6e-15 56.2 0.2 1.7 2 0 0 2 2 2 1 NLE (NUC135) domain WD40 PF00400.32 KXH65283.1 - 1.9e-10 41.1 4.8 0.093 13.6 0.0 4.6 4 0 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.8 KXH65283.1 - 0.0058 15.3 0.3 0.047 12.3 0.1 2.0 2 0 0 2 2 2 1 Nucleoporin Nup120/160 MIF4G_like PF09088.11 KXH65284.1 - 1.2e-90 302.4 0.1 1.8e-90 301.8 0.1 1.3 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.11 KXH65284.1 - 3.8e-74 249.5 0.0 6.9e-74 248.7 0.0 1.5 1 0 0 1 1 1 1 MIF4G like Tape_meas_lam_C PF09718.10 KXH65284.1 - 0.13 12.4 0.6 0.49 10.6 0.1 2.1 2 0 0 2 2 2 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) Pkinase PF00069.25 KXH65285.1 - 2.3e-64 217.3 0.0 2.8e-64 217.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXH65285.1 - 3.5e-25 88.8 0.0 4.5e-25 88.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXH65285.1 - 2.1e-06 27.3 0.0 9.9e-06 25.1 0.0 1.9 1 1 1 2 2 2 1 Kinase-like APH PF01636.23 KXH65285.1 - 0.0033 17.4 0.2 0.014 15.3 0.0 1.9 2 1 1 3 3 3 1 Phosphotransferase enzyme family DUF1229 PF06797.11 KXH65285.1 - 0.006 16.8 0.2 0.0095 16.2 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1229) Kdo PF06293.14 KXH65285.1 - 0.1 11.9 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KXH65285.1 - 0.14 11.7 0.0 0.25 10.9 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 PX PF00787.24 KXH65296.1 - 6.9e-17 61.5 0.0 1.1e-16 60.8 0.0 1.3 1 0 0 1 1 1 1 PX domain SlyX PF04102.12 KXH65296.1 - 0.91 10.2 5.1 2.4 8.8 0.2 2.8 1 1 1 2 2 2 0 SlyX EB1 PF03271.17 KXH65297.1 - 2.2e-17 63.0 2.1 4.7e-17 61.9 2.1 1.6 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.31 KXH65297.1 - 2.6e-07 30.8 0.8 4.8e-07 29.9 0.8 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain CH_2 PF06294.11 KXH65297.1 - 0.049 13.7 0.3 0.076 13.1 0.3 1.4 1 0 0 1 1 1 0 CH-like domain in sperm protein DEAD PF00270.29 KXH65298.1 - 1.8e-45 154.8 0.1 1.8e-45 154.8 0.1 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXH65298.1 - 3e-30 104.8 0.2 3.7e-29 101.3 0.2 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF2183 PF09949.9 KXH65298.1 - 2.1e-26 92.1 0.0 7.4e-26 90.4 0.0 2.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) UTP25 PF06862.12 KXH65298.1 - 0.00074 18.4 1.5 0.001 17.9 0.1 1.9 2 1 1 3 3 3 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Pectate_lyase PF03211.13 KXH65299.1 - 9.4e-76 253.9 10.8 1.3e-75 253.4 10.8 1.1 1 0 0 1 1 1 1 Pectate lyase Beta-lactamase PF00144.24 KXH65300.1 - 9.1e-36 123.7 0.2 1.4e-35 123.2 0.2 1.2 1 0 0 1 1 1 1 Beta-lactamase BTRD1 PF17660.1 KXH65300.1 - 4.3e-34 116.1 1.5 4.9e-13 48.7 0.1 4.2 4 0 0 4 4 4 3 Bacterial tandem repeat domain 1 p450 PF00067.22 KXH65301.1 - 1.8e-68 231.4 0.0 2.3e-68 231.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Hira PF07569.11 KXH65301.1 - 0.033 13.9 0.1 0.4 10.4 0.0 2.2 2 0 0 2 2 2 0 TUP1-like enhancer of split Sugar_tr PF00083.24 KXH65302.1 - 4.2e-98 329.1 17.4 4.9e-98 328.9 17.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH65302.1 - 4.8e-33 114.6 41.6 1.5e-26 93.2 20.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4017 PF13209.6 KXH65302.1 - 4.1 7.4 8.3 2.3 8.2 0.2 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4017) GWT1 PF06423.12 KXH65303.1 - 0.11 12.6 1.6 0.16 12.1 1.6 1.3 1 0 0 1 1 1 0 GWT1 adh_short_C2 PF13561.6 KXH65304.1 - 2.2e-61 207.4 1.9 2.6e-61 207.2 1.9 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXH65304.1 - 9e-40 136.2 1.2 1.1e-39 136.0 1.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXH65304.1 - 7e-15 55.4 0.4 1e-14 54.8 0.4 1.2 1 0 0 1 1 1 1 KR domain YjeF_N PF03853.15 KXH65304.1 - 0.034 14.1 0.1 0.092 12.6 0.1 1.7 2 0 0 2 2 2 0 YjeF-related protein N-terminus SRF-TF PF00319.18 KXH65304.1 - 0.069 12.7 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 SRF-type transcription factor (DNA-binding and dimerisation domain) Alpha-2-MRAP_C PF06401.11 KXH65304.1 - 0.076 13.0 0.1 0.45 10.4 0.0 1.9 2 0 0 2 2 2 0 Alpha-2-macroglobulin RAP, C-terminal domain Glyoxalase_3 PF13468.6 KXH65306.1 - 8.4e-21 74.9 0.0 1.3e-20 74.2 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase-like domain Cellulase PF00150.18 KXH65307.1 - 7.9e-47 160.0 0.0 1.1e-46 159.6 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) SOG2 PF10428.9 KXH65307.1 - 3.1 6.9 10.2 4.1 6.5 10.2 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Lactamase_B_4 PF13691.6 KXH65308.1 - 1.3e-20 72.8 0.1 1.9e-19 69.1 0.0 2.3 2 0 0 2 2 2 1 tRNase Z endonuclease Lactamase_B_2 PF12706.7 KXH65308.1 - 2.3e-15 56.6 0.0 4.8e-15 55.6 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KXH65308.1 - 0.00085 19.4 0.0 0.0021 18.1 0.0 1.7 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Flavin_Reduct PF01613.18 KXH65309.1 - 8.6e-16 58.4 0.0 1.4e-15 57.7 0.0 1.3 1 0 0 1 1 1 1 Flavin reductase like domain PDEase_II PF02112.15 KXH65310.1 - 2e-49 168.5 0.2 5.9e-43 147.3 0.2 2.9 2 1 0 2 2 2 2 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.7 KXH65310.1 - 0.12 11.8 0.0 0.27 10.7 0.0 1.6 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Acyl_transf_3 PF01757.22 KXH65312.1 - 2.9e-31 108.8 28.1 7.4e-31 107.4 28.1 1.7 1 1 0 1 1 1 1 Acyltransferase family AMP-binding PF00501.28 KXH65313.1 - 1.3e-65 221.6 0.4 2.6e-35 121.9 0.0 4.2 2 2 0 2 2 2 2 AMP-binding enzyme DMAP_binding PF06464.11 KXH65313.1 - 8.5e-10 39.4 0.0 2e-09 38.3 0.0 1.6 1 0 0 1 1 1 1 DMAP1-binding Domain GvpG PF05120.12 KXH65313.1 - 0.026 14.5 1.6 0.065 13.2 1.6 1.6 1 0 0 1 1 1 0 Gas vesicle protein G Transferase PF02458.15 KXH65315.1 - 2.8e-12 46.0 0.0 3.7e-12 45.6 0.0 1.1 1 0 0 1 1 1 1 Transferase family Glyco_hydro81C PF17652.1 KXH65316.1 - 2.8e-131 437.9 5.1 4.5e-131 437.2 5.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 KXH65316.1 - 1.3e-103 346.6 0.9 1.7e-103 346.2 0.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 N-terminal domain Glu_cyclase_2 PF05096.12 KXH65316.1 - 0.015 14.8 0.0 0.026 13.9 0.0 1.3 1 0 0 1 1 1 0 Glutamine cyclotransferase Fungal_trans PF04082.18 KXH65317.1 - 1.4e-09 37.4 0.4 2.2e-09 36.8 0.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXH65317.1 - 1e-05 25.6 7.3 1.7e-05 24.9 7.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LigB PF02900.18 KXH65318.1 - 3.7e-26 91.8 0.0 4.6e-26 91.5 0.0 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Shisa PF13908.6 KXH65319.1 - 0.04 14.2 0.0 0.057 13.7 0.0 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Glyco_transf_25 PF01755.17 KXH65320.1 - 1.2e-15 57.9 0.0 4.8e-11 42.9 0.0 2.1 2 0 0 2 2 2 2 Glycosyltransferase family 25 (LPS biosynthesis protein) Methyltransf_23 PF13489.6 KXH65321.1 - 3.5e-19 69.2 0.0 6.1e-19 68.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH65321.1 - 1.4e-08 35.3 0.0 4.1e-08 33.8 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH65321.1 - 7.4e-07 29.1 0.0 7.9e-06 25.7 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH65321.1 - 1.8e-05 25.3 0.0 4.2e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH65321.1 - 0.00059 20.5 0.1 0.0089 16.7 0.1 2.6 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KXH65321.1 - 0.0051 16.2 0.0 0.0087 15.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KXH65321.1 - 0.0057 16.2 0.0 0.0086 15.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.18 KXH65321.1 - 0.012 14.9 0.0 0.018 14.4 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain GidB PF02527.15 KXH65321.1 - 0.04 13.2 0.0 0.24 10.7 0.0 1.9 2 0 0 2 2 2 0 rRNA small subunit methyltransferase G PCMT PF01135.19 KXH65321.1 - 0.06 13.1 0.1 0.11 12.2 0.1 1.4 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.20 KXH65321.1 - 0.11 11.7 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase RrnaAD PF00398.20 KXH65321.1 - 0.15 11.1 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase FAD_binding_4 PF01565.23 KXH65323.1 - 5.2e-25 87.8 4.7 8.5e-25 87.1 4.7 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KXH65323.1 - 8.6e-06 25.8 0.0 1.6e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Berberine and berberine like ALO PF04030.14 KXH65323.1 - 0.14 11.9 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 D-arabinono-1,4-lactone oxidase Methyltransf_23 PF13489.6 KXH65325.1 - 3.7e-20 72.4 0.0 6e-20 71.7 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH65325.1 - 9.6e-12 45.5 0.0 2.8e-11 44.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH65325.1 - 4.5e-09 36.3 0.0 1e-07 31.8 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH65325.1 - 1.8e-07 31.7 0.0 3.5e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH65325.1 - 4.6e-07 30.5 0.0 3.3e-06 27.8 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KXH65325.1 - 0.00043 19.8 0.0 0.0026 17.3 0.0 2.1 2 0 0 2 2 2 1 Putative methyltransferase PrmA PF06325.13 KXH65325.1 - 0.0039 16.6 0.0 0.0068 15.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KXH65325.1 - 0.0086 15.6 0.0 0.021 14.4 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain Ubie_methyltran PF01209.18 KXH65325.1 - 0.013 14.9 0.0 0.048 13.0 0.0 1.8 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family FtsJ PF01728.19 KXH65325.1 - 0.04 14.0 0.0 0.069 13.3 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase DUF938 PF06080.12 KXH65325.1 - 0.073 12.8 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) P_C PF06640.11 KXH65325.1 - 0.12 12.5 3.1 0.24 11.5 3.1 1.4 1 0 0 1 1 1 0 P protein C-terminus Methyltransf_16 PF10294.9 KXH65325.1 - 0.14 11.9 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_23 PF13489.6 KXH65326.1 - 2.1e-18 66.7 0.0 3.8e-18 65.9 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH65326.1 - 5e-10 40.0 0.0 1.8e-09 38.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH65326.1 - 1.1e-06 29.1 0.0 3.4e-06 27.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH65326.1 - 1.2e-06 28.5 0.0 0.0013 18.5 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 KXH65326.1 - 6.7e-05 23.6 0.0 0.001 19.7 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXH65326.1 - 0.0022 17.4 0.0 0.16 11.3 0.0 2.1 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 KXH65326.1 - 0.0064 16.0 0.0 0.016 14.7 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.14 KXH65326.1 - 0.012 15.2 0.0 0.023 14.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain FtsJ PF01728.19 KXH65326.1 - 0.025 14.7 0.0 0.035 14.2 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase PrmA PF06325.13 KXH65326.1 - 0.03 13.7 0.0 0.061 12.7 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.9 KXH65326.1 - 0.091 12.5 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase HAD_2 PF13419.6 KXH65328.1 - 3.2e-07 30.6 0.0 4.8e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KXH65328.1 - 0.00012 22.1 0.0 0.00025 21.0 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 KXH65328.1 - 0.0012 19.1 0.0 0.0019 18.5 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase PG_binding_1 PF01471.18 KXH65328.1 - 0.16 12.2 0.0 0.5 10.6 0.0 1.8 2 0 0 2 2 2 0 Putative peptidoglycan binding domain bZIP_1 PF00170.21 KXH65329.1 - 0.0028 17.7 7.7 0.011 15.8 7.7 2.0 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KXH65329.1 - 0.018 15.1 7.3 0.018 15.1 7.3 1.9 2 0 0 2 2 2 0 Basic region leucine zipper IL2 PF00715.17 KXH65329.1 - 0.077 12.9 0.2 0.34 10.8 0.0 2.1 2 0 0 2 2 2 0 Interleukin 2 COesterase PF00135.28 KXH65330.1 - 2.9e-79 267.3 0.0 3.8e-79 266.9 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXH65330.1 - 2.9e-07 30.6 1.4 6.9e-07 29.3 0.3 2.2 2 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KXH65330.1 - 0.0098 15.4 0.1 0.12 11.9 0.0 2.3 2 0 0 2 2 2 1 Prolyl oligopeptidase family DUF4265 PF14085.6 KXH65330.1 - 0.032 14.2 0.0 0.059 13.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4265) Acetyltransf_1 PF00583.25 KXH65332.1 - 1.8e-05 25.0 0.0 2.7e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 KXH65332.1 - 1.8e-05 24.6 0.0 2.9e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 KXH65332.1 - 0.023 15.4 0.0 0.034 14.8 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 KXH65332.1 - 0.17 11.4 0.1 0.25 10.9 0.1 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase Pro_CA PF00484.19 KXH65333.1 - 5.1e-51 173.0 0.0 7.2e-51 172.6 0.0 1.2 1 0 0 1 1 1 1 Carbonic anhydrase DUF4448 PF14610.6 KXH65334.1 - 2.7e-28 99.0 0.2 8.6e-20 71.3 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF4448) DUF2207 PF09972.9 KXH65334.1 - 0.027 13.3 0.0 0.042 12.6 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) TMEM171 PF15471.6 KXH65334.1 - 0.17 10.9 0.0 0.25 10.3 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein family 171 CAAD PF14159.6 KXH65334.1 - 0.3 10.9 1.0 0.58 10.0 1.0 1.4 1 0 0 1 1 1 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase Dynactin_p62 PF05502.13 KXH65335.1 - 2.5e-208 692.7 3.7 6.1e-208 691.4 3.7 1.5 1 1 0 1 1 1 1 Dynactin p62 family zf-H2C2_2 PF13465.6 KXH65339.1 - 0.077 13.5 5.9 0.64 10.5 1.5 3.0 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 KXH65339.1 - 0.65 11.0 9.4 0.36 11.8 0.8 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KXH65339.1 - 0.67 10.5 11.2 1.7 9.2 0.9 3.6 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 KXH65339.1 - 0.8 9.5 3.0 2.1 8.2 3.0 1.8 1 0 0 1 1 1 0 C2H2-type zinc-finger domain zf-MIZ PF02891.20 KXH65342.1 - 0.062 13.1 1.4 0.15 11.8 1.4 1.7 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-RING_UBOX PF13445.6 KXH65342.1 - 0.57 10.2 5.1 0.39 10.8 2.2 2.3 2 0 0 2 2 2 0 RING-type zinc-finger Formyl_trans_N PF00551.19 KXH65343.1 - 3.7e-36 124.6 0.1 4.8e-36 124.2 0.1 1.2 1 0 0 1 1 1 1 Formyl transferase ACT PF01842.25 KXH65343.1 - 8.1e-08 31.9 0.0 1.9e-07 30.7 0.0 1.7 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.6 KXH65343.1 - 0.034 14.1 0.1 0.21 11.6 0.0 2.3 3 0 0 3 3 3 0 ACT domain Asp PF00026.23 KXH65344.1 - 3.4e-05 23.4 0.1 0.0076 15.7 0.0 2.1 2 0 0 2 2 2 2 Eukaryotic aspartyl protease VSP PF03302.13 KXH65344.1 - 0.0076 15.2 0.6 0.011 14.7 0.6 1.1 1 0 0 1 1 1 1 Giardia variant-specific surface protein Cutinase PF01083.22 KXH65345.1 - 6.5e-46 156.5 1.9 8.2e-46 156.2 1.9 1.1 1 0 0 1 1 1 1 Cutinase DUF2974 PF11187.8 KXH65345.1 - 0.0062 16.1 0.1 0.0094 15.5 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) PE-PPE PF08237.11 KXH65345.1 - 0.01 15.4 0.3 0.018 14.6 0.3 1.4 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_1 PF00561.20 KXH65345.1 - 0.029 14.0 0.0 0.035 13.7 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 KXH65345.1 - 0.053 13.4 0.6 0.091 12.6 0.6 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 KXH65345.1 - 0.058 12.3 0.1 0.086 11.7 0.1 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme VirJ PF06057.11 KXH65345.1 - 0.06 13.2 0.0 0.095 12.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Lipase_3 PF01764.25 KXH65345.1 - 0.067 13.1 0.1 0.088 12.7 0.1 1.3 1 0 0 1 1 1 0 Lipase (class 3) Methyltransf_23 PF13489.6 KXH65349.1 - 8.6e-19 68.0 0.0 1.3e-18 67.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXH65349.1 - 1.4e-09 38.6 0.0 3.2e-09 37.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXH65349.1 - 5.1e-08 32.9 0.0 4.5e-07 29.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXH65349.1 - 7.8e-07 29.7 0.0 2e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXH65349.1 - 6.4e-06 26.8 0.0 5.7e-05 23.8 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXH65349.1 - 0.049 13.2 0.0 0.095 12.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_4 PF02390.17 KXH65349.1 - 0.14 11.6 0.0 0.3 10.5 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase O-antigen_lig PF13425.6 KXH65350.1 - 0.0084 14.9 1.4 0.01 14.7 1.4 1.1 1 0 0 1 1 1 1 O-antigen ligase like membrane protein RXLR PF16810.5 KXH65350.1 - 0.37 11.2 11.2 0.71 10.3 11.2 1.7 1 1 0 1 1 1 0 RXLR phytopathogen effector protein, Avirulence activity Hamartin PF04388.12 KXH65350.1 - 4.7 5.7 10.2 5.8 5.5 10.2 1.0 1 0 0 1 1 1 0 Hamartin protein Presenilin PF01080.17 KXH65350.1 - 5.7 5.6 8.2 6.3 5.4 8.2 1.3 1 0 0 1 1 1 0 Presenilin Macoilin PF09726.9 KXH65350.1 - 7.6 5.0 15.4 9.6 4.6 15.4 1.1 1 0 0 1 1 1 0 Macoilin family NmrA PF05368.13 KXH65351.1 - 2.7e-18 66.4 0.0 3.6e-18 66.0 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXH65351.1 - 6.1e-09 36.0 0.1 1.1e-08 35.2 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KXH65351.1 - 0.00022 20.8 0.0 0.00034 20.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXH65351.1 - 0.033 13.2 0.0 0.074 12.0 0.0 1.6 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Sacchrp_dh_NADP PF03435.18 KXH65351.1 - 0.12 12.6 0.0 0.28 11.4 0.0 1.7 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain RibD_C PF01872.17 KXH65352.1 - 3.7e-18 66.1 0.0 6.6e-18 65.3 0.0 1.4 1 1 0 1 1 1 1 RibD C-terminal domain DHFR_1 PF00186.19 KXH65352.1 - 1.6e-05 24.7 0.0 2.1e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Dihydrofolate reductase NAD_binding_10 PF13460.6 KXH65353.1 - 8.5e-08 32.3 0.0 1.9e-07 31.1 0.0 1.6 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KXH65353.1 - 2.4e-05 24.0 0.0 0.018 14.6 0.0 2.1 2 0 0 2 2 2 2 NmrA-like family Epimerase PF01370.21 KXH65353.1 - 0.0096 15.4 0.0 0.096 12.1 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KXH65353.1 - 0.078 12.1 0.0 0.17 11.0 0.0 1.5 1 0 0 1 1 1 0 RmlD substrate binding domain Glyco_hydro_106 PF17132.4 KXH65354.1 - 1.2e-07 30.5 0.0 0.0003 19.2 0.0 3.0 2 1 0 2 2 2 2 alpha-L-rhamnosidase Glyco_hydro_42M PF08532.10 KXH65354.1 - 0.0034 16.9 0.0 0.0064 16.0 0.0 1.4 1 0 0 1 1 1 1 Beta-galactosidase trimerisation domain Melibiase PF02065.18 KXH65355.1 - 1.9e-36 125.7 0.1 2.8e-36 125.2 0.1 1.2 1 0 0 1 1 1 1 Melibiase Glyco_hydro_36N PF16875.5 KXH65355.1 - 2.6e-09 37.0 0.0 4.6e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 36 N-terminal domain Melibiase_2 PF16499.5 KXH65355.1 - 0.00095 18.4 0.0 0.0017 17.6 0.0 1.4 1 0 0 1 1 1 1 Alpha galactosidase A Glyco_hydro_127 PF07944.12 KXH65356.1 - 8.1e-115 384.2 0.1 1e-114 383.9 0.1 1.0 1 0 0 1 1 1 1 Beta-L-arabinofuranosidase, GH127 BRO1 PF03097.18 KXH65356.1 - 0.13 11.0 0.1 0.19 10.5 0.1 1.1 1 0 0 1 1 1 0 BRO1-like domain Sugar_tr PF00083.24 KXH65357.1 - 5.4e-67 226.6 17.4 5.4e-67 226.6 17.4 1.4 1 1 1 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH65357.1 - 6.6e-17 61.5 24.4 6.6e-17 61.5 24.4 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Trehalase PF01204.18 KXH65359.1 - 1e-09 37.8 0.1 1.5e-09 37.2 0.1 1.2 1 0 0 1 1 1 1 Trehalase Glyco_hydro_63 PF03200.16 KXH65359.1 - 1.3e-06 27.5 2.5 0.15 10.8 0.2 3.8 2 1 1 3 3 3 2 Glycosyl hydrolase family 63 C-terminal domain DNA_pol_A_exoN PF18305.1 KXH65359.1 - 0.063 13.6 0.6 0.58 10.5 0.5 2.4 2 0 0 2 2 2 0 3' to 5' exonuclease C-terminal domain DUF3995 PF13160.6 KXH65361.1 - 0.19 12.1 5.5 0.43 11.0 2.2 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF3995) Neuraminidase PF18413.1 KXH65361.1 - 0.2 11.3 0.2 0.32 10.6 0.2 1.2 1 0 0 1 1 1 0 Neuraminidase-like domain Methyltransf_2 PF00891.18 KXH65362.1 - 5.4e-17 61.8 0.0 9.9e-17 60.9 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain GFO_IDH_MocA_C PF02894.17 KXH65363.1 - 4.1e-17 62.2 0.3 1.3e-16 60.6 0.3 1.9 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain GFO_IDH_MocA PF01408.22 KXH65363.1 - 3e-16 60.3 0.0 5.6e-16 59.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold MFS_1 PF07690.16 KXH65364.1 - 5.9e-33 114.2 31.8 5.9e-33 114.2 31.8 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Cutinase PF01083.22 KXH65365.1 - 5.8e-41 140.4 0.4 7e-41 140.1 0.4 1.1 1 0 0 1 1 1 1 Cutinase Hydrolase_4 PF12146.8 KXH65365.1 - 0.0021 17.4 0.0 0.0031 16.8 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PE-PPE PF08237.11 KXH65365.1 - 0.0093 15.5 0.0 0.013 15.0 0.0 1.2 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_2 PF02230.16 KXH65365.1 - 0.024 14.4 0.0 0.045 13.6 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Amidohydro_3 PF07969.11 KXH65366.1 - 1.1e-67 229.5 4.3 1.3e-67 229.3 4.3 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 KXH65366.1 - 3.7e-14 52.8 0.1 4.5e-09 36.1 0.0 2.7 2 1 0 2 2 2 2 Amidohydrolase family Dynamin_N PF00350.23 KXH65367.1 - 4e-16 59.5 0.0 1.6e-15 57.6 0.0 2.1 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 KXH65367.1 - 0.00025 21.1 0.2 0.0075 16.3 0.1 2.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase AIG1 PF04548.16 KXH65367.1 - 0.0036 16.6 0.0 0.029 13.7 0.0 2.2 2 0 0 2 2 2 1 AIG1 family GTP_EFTU PF00009.27 KXH65367.1 - 0.013 15.1 1.8 0.86 9.1 1.4 2.9 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 KXH65367.1 - 0.024 15.1 0.0 0.11 13.0 0.0 2.2 1 0 0 1 1 1 0 ABC transporter AAA_16 PF13191.6 KXH65367.1 - 0.033 14.6 0.6 0.5 10.7 0.0 3.0 2 1 0 2 2 2 0 AAA ATPase domain RsgA_GTPase PF03193.16 KXH65367.1 - 0.043 13.7 0.0 0.18 11.7 0.0 2.1 1 0 0 1 1 1 0 RsgA GTPase IIGP PF05049.13 KXH65367.1 - 0.1 11.6 0.0 0.45 9.5 0.0 2.0 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) MHB PF16525.5 KXH65367.1 - 0.13 12.5 0.1 0.56 10.5 0.1 2.1 1 0 0 1 1 1 0 Haemophore, haem-binding DUF87 PF01935.17 KXH65367.1 - 0.22 11.6 2.4 0.38 10.8 0.0 2.7 3 1 0 3 3 3 0 Helicase HerA, central domain DASH_Spc19 PF08287.11 KXH65367.1 - 0.74 9.7 7.7 0.25 11.2 3.3 2.5 2 0 0 2 2 2 0 Spc19 HNH_2 PF13391.6 KXH65368.1 - 0.012 15.7 0.0 0.035 14.2 0.0 1.9 2 1 0 2 2 2 0 HNH endonuclease Herpes_US12 PF05363.12 KXH65368.1 - 0.084 13.6 0.0 14 6.5 0.0 2.4 2 0 0 2 2 2 0 Herpesvirus US12 family BHD_1 PF10403.9 KXH65369.1 - 0.053 13.4 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Rad4 beta-hairpin domain 1 HET PF06985.11 KXH65370.1 - 1e-05 25.9 5.0 0.004 17.5 0.1 2.8 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) TPR_12 PF13424.6 KXH65371.1 - 0.00014 22.1 6.1 4.7 7.6 0.0 5.6 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_10 PF13374.6 KXH65371.1 - 0.026 14.4 3.8 11 6.0 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 KXH65371.1 - 0.049 13.8 1.8 3.9 7.8 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Peptidase_M14 PF00246.24 KXH65372.1 - 7e-75 252.5 0.1 8.4e-75 252.2 0.1 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase K_channel_TID PF07941.11 KXH65372.1 - 0.053 14.0 0.1 0.18 12.3 0.1 1.9 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain F-box-like PF12937.7 KXH65373.1 - 4.1e-05 23.4 0.0 8.8e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXH65373.1 - 0.022 14.6 3.4 0.5 10.3 2.4 3.1 1 1 1 2 2 2 0 F-box domain Rsa3 PF14615.6 KXH65373.1 - 0.025 14.1 0.1 0.12 12.0 0.0 2.2 2 0 0 2 2 2 0 Ribosome-assembly protein 3 CAAP1 PF15335.6 KXH65373.1 - 0.079 13.5 0.0 0.17 12.4 0.0 1.6 1 0 0 1 1 1 0 Caspase activity and apoptosis inhibitor 1 F-box_4 PF15966.5 KXH65374.1 - 0.0011 18.8 0.0 0.0069 16.3 0.0 2.2 2 0 0 2 2 2 1 F-box F-box-like PF12937.7 KXH65374.1 - 0.0056 16.6 0.0 0.013 15.4 0.0 1.7 1 0 0 1 1 1 1 F-box-like VacA2 PF03077.14 KXH65375.1 - 0.15 11.9 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 Putative vacuolating cytotoxin Tyrosinase PF00264.20 KXH65376.1 - 7.4e-45 153.9 0.0 1.5e-44 152.9 0.0 1.5 1 0 0 1 1 1 1 Common central domain of tyrosinase RIO1 PF01163.22 KXH65377.1 - 3.4e-69 232.2 0.0 7.6e-69 231.1 0.0 1.6 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 KXH65377.1 - 0.0018 18.3 0.1 1.1 9.2 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 KXH65377.1 - 0.022 14.1 0.0 0.62 9.4 0.0 2.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family B12D PF06522.11 KXH65379.1 - 0.069 13.0 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 NADH-ubiquinone reductase complex 1 MLRQ subunit Sulfotransfer_4 PF17784.1 KXH65380.1 - 2.2e-62 210.7 0.1 2.9e-62 210.3 0.1 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KXH65380.1 - 0.00032 21.2 0.1 0.0017 18.8 0.1 2.0 1 1 0 1 1 1 1 Sulfotransferase family Ank_2 PF12796.7 KXH65381.1 - 4.3e-10 40.1 0.1 0.013 16.1 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXH65381.1 - 2e-05 24.6 3.2 8.1 7.4 0.0 6.8 7 0 0 7 7 7 1 Ankyrin repeat Ank PF00023.30 KXH65381.1 - 2.9e-05 24.3 4.4 1.4 9.4 0.0 6.1 7 0 0 7 7 7 1 Ankyrin repeat Ank_4 PF13637.6 KXH65381.1 - 3e-05 24.5 3.5 7 7.4 0.2 5.4 5 2 2 7 7 7 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXH65381.1 - 0.00061 20.0 2.1 0.23 11.8 0.0 4.6 6 0 0 6 6 6 1 Ankyrin repeats (many copies) SUKH-4 PF14435.6 KXH65381.1 - 0.06 13.4 0.2 0.14 12.2 0.1 1.6 1 1 0 1 1 1 0 SUKH-4 immunity protein PUF PF00806.19 KXH65384.1 - 0.016 14.9 0.0 0.03 14.0 0.0 1.4 1 0 0 1 1 1 0 Pumilio-family RNA binding repeat PNGaseA PF12222.8 KXH65402.1 - 1e-147 492.5 3.2 1.3e-147 492.1 3.2 1.1 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A ssDBP PF17878.1 KXH65402.1 - 0.041 14.1 0.1 0.12 12.7 0.1 1.7 1 0 0 1 1 1 0 Single-stranded DNA-binding protein adh_short PF00106.25 KXH65403.1 - 4.5e-24 85.0 0.1 6e-24 84.6 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXH65403.1 - 3.3e-20 72.7 0.0 4e-20 72.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH65403.1 - 8.9e-18 64.8 0.2 1.2e-17 64.4 0.2 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KXH65403.1 - 3.4e-07 29.7 0.0 4.5e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KXH65403.1 - 3.5e-05 23.4 0.0 4.6e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family ThiF PF00899.21 KXH65403.1 - 0.0047 16.3 0.6 1 8.7 0.1 2.4 2 1 0 2 2 2 2 ThiF family GDP_Man_Dehyd PF16363.5 KXH65403.1 - 0.01 15.3 0.0 0.012 15.0 0.0 1.1 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Eno-Rase_NADH_b PF12242.8 KXH65403.1 - 0.075 12.8 0.3 0.15 11.8 0.3 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Shikimate_DH PF01488.20 KXH65403.1 - 0.19 11.8 0.2 0.31 11.1 0.2 1.5 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase LysM PF01476.20 KXH65404.1 - 2.9e-07 30.5 0.0 0.0053 16.8 0.0 3.5 3 0 0 3 3 3 3 LysM domain Zn_clus PF00172.18 KXH65405.1 - 7.2e-10 38.8 4.9 1.5e-09 37.9 4.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KXH65405.1 - 0.00083 18.3 0.3 0.0051 15.7 0.1 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain BTB PF00651.31 KXH65406.1 - 0.0086 16.3 0.0 0.027 14.7 0.0 1.8 1 1 0 1 1 1 1 BTB/POZ domain F-box-like PF12937.7 KXH65407.1 - 0.0059 16.5 0.1 0.015 15.2 0.1 1.7 1 0 0 1 1 1 1 F-box-like Cas_Csm6 PF09659.10 KXH65407.1 - 0.085 11.6 0.1 0.12 11.1 0.1 1.1 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csm6) DAO PF01266.24 KXH65408.1 - 4.1e-19 69.4 0.1 6.8e-19 68.6 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Formyl_trans_N PF00551.19 KXH65408.1 - 2.1e-10 40.6 0.0 3.9e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 Formyl transferase NAD_binding_8 PF13450.6 KXH65408.1 - 9e-05 22.6 0.0 0.00029 21.0 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KXH65408.1 - 0.00099 19.6 0.0 0.35 11.5 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXH65408.1 - 0.0016 17.8 0.0 1.4 8.1 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KXH65408.1 - 0.002 17.4 0.0 0.0041 16.4 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KXH65408.1 - 0.033 12.9 0.1 6 5.4 0.0 2.3 2 0 0 2 2 2 0 HI0933-like protein 3HCDH_N PF02737.18 KXH65408.1 - 0.038 13.9 0.0 0.064 13.1 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 KXH65408.1 - 0.093 11.8 0.0 0.17 10.9 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Shikimate_DH PF01488.20 KXH65408.1 - 0.16 12.0 0.0 0.31 11.1 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase AlaDh_PNT_C PF01262.21 KXH65408.1 - 0.22 10.8 0.0 0.41 9.9 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain MFS_1 PF07690.16 KXH65409.1 - 1e-35 123.3 35.4 1e-35 123.3 35.4 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily GATase PF00117.28 KXH65410.1 - 3.5e-12 46.5 0.0 4.8e-12 46.1 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KXH65410.1 - 0.0063 16.3 0.1 0.12 12.1 0.1 2.5 1 1 0 1 1 1 1 Peptidase C26 Sortilin-Vps10 PF15902.5 KXH65411.1 - 4.7e-14 52.0 4.7 0.00023 20.1 0.0 5.7 4 2 2 7 7 7 5 Sortilin, neurotensin receptor 3, CBM_1 PF00734.18 KXH65411.1 - 3.6e-12 46.0 17.3 1e-11 44.6 17.3 1.9 1 0 0 1 1 1 1 Fungal cellulose binding domain BNR PF02012.20 KXH65411.1 - 0.00011 21.7 31.2 1.7 9.0 0.1 9.3 10 0 0 10 10 9 3 BNR/Asp-box repeat BNR_2 PF13088.6 KXH65411.1 - 0.0018 17.6 13.7 0.46 9.7 0.0 5.7 4 2 1 5 5 5 2 BNR repeat-like domain Kelch_4 PF13418.6 KXH65411.1 - 0.012 15.6 1.2 0.044 13.8 0.2 2.6 2 0 0 2 2 2 0 Galactose oxidase, central domain BNR_6 PF15899.5 KXH65411.1 - 0.013 15.5 10.5 5.6 7.3 0.1 6.5 7 0 0 7 7 7 0 BNR-Asp box repeat Toxin_7 PF05980.12 KXH65411.1 - 0.028 14.6 2.0 0.049 13.9 2.0 1.4 1 0 0 1 1 1 0 Toxin 7 Kelch_1 PF01344.25 KXH65411.1 - 0.052 13.1 1.4 0.11 12.1 0.2 2.3 2 0 0 2 2 2 0 Kelch motif Kelch_3 PF13415.6 KXH65411.1 - 0.064 13.6 0.5 0.064 13.6 0.5 4.0 5 1 0 5 5 5 0 Galactose oxidase, central domain BNR_3 PF13859.6 KXH65411.1 - 0.29 10.4 5.5 3.1 7.0 0.0 4.3 4 1 1 5 5 5 0 BNR repeat-like domain Paramyxo_P_V_N PF13825.6 KXH65411.1 - 6.1 6.2 13.2 11 5.3 13.2 1.3 1 0 0 1 1 1 0 Paramyxovirus structural protein V/P N-terminus Sugar_tr PF00083.24 KXH65412.1 - 3.4e-88 296.5 26.8 4e-88 296.3 26.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXH65412.1 - 8.6e-37 126.9 23.1 8.6e-37 126.9 23.1 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KXH65412.1 - 1.5e-05 23.7 4.8 1.5e-05 23.7 4.8 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 KXH65412.1 - 0.00025 19.5 2.9 0.00025 19.5 2.9 3.5 1 1 1 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family RseC_MucC PF04246.12 KXH65412.1 - 1.3 9.0 3.4 1.6 8.7 0.7 2.6 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Glyco_hydro_2_C PF02836.17 KXH65413.1 - 1.3e-100 336.4 0.1 2e-100 335.8 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.17 KXH65413.1 - 1.3e-64 218.1 0.0 2.5e-64 217.2 0.0 1.4 1 0 0 1 1 1 1 Beta galactosidase small chain Glyco_hydro_2_N PF02837.18 KXH65413.1 - 4.2e-40 137.4 0.3 8.4e-40 136.4 0.3 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain DUF4981 PF16353.5 KXH65413.1 - 3.9e-21 75.3 0.0 1.2e-20 73.8 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function(DUF4981) Glyco_hydro_2 PF00703.21 KXH65413.1 - 1.9e-11 44.6 0.1 1.7e-10 41.5 0.0 2.4 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.6 KXH65413.1 - 0.022 15.3 0.0 0.068 13.8 0.0 1.8 1 0 0 1 1 1 0 Beta-galactosidase jelly roll domain Mito_carr PF00153.27 KXH65415.1 - 3.1e-38 129.6 7.6 3.4e-16 58.9 0.4 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Aminotran_4 PF01063.19 KXH65416.1 - 2.1e-20 73.5 0.0 4.4e-20 72.5 0.0 1.5 1 1 0 1 1 1 1 Amino-transferase class IV 2-Hacid_dh_C PF02826.19 KXH65417.1 - 3e-37 127.7 0.0 1e-36 126.0 0.0 1.8 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 KXH65417.1 - 2.1e-05 24.7 0.0 3.2e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh PF00389.30 KXH65417.1 - 0.0002 21.1 0.0 0.00048 19.8 0.0 1.7 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain F420_oxidored PF03807.17 KXH65417.1 - 0.00022 21.7 0.0 0.00039 20.9 0.0 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent AlaDh_PNT_C PF01262.21 KXH65417.1 - 0.00073 18.9 0.0 0.0012 18.2 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_Gly3P_dh_N PF01210.23 KXH65417.1 - 0.0025 17.8 0.0 0.0036 17.3 0.0 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus XdhC_C PF13478.6 KXH65417.1 - 0.0054 17.2 0.0 0.0097 16.4 0.0 1.5 1 0 0 1 1 1 1 XdhC Rossmann domain 3HCDH_N PF02737.18 KXH65417.1 - 0.0063 16.4 0.0 0.0097 15.8 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 KXH65417.1 - 0.015 15.0 0.0 0.023 14.3 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.27 KXH65417.1 - 0.032 14.8 0.0 0.065 13.8 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 KXH65417.1 - 0.033 14.4 0.1 0.097 12.9 0.1 1.8 2 0 0 2 2 2 0 TrkA-N domain Pyr_redox_2 PF07992.14 KXH65417.1 - 0.038 13.2 0.0 0.066 12.4 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 KXH65417.1 - 0.051 14.0 0.0 0.1 13.0 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.14 KXH65417.1 - 0.079 12.5 0.0 0.16 11.5 0.0 1.6 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain RRM_7 PF16367.5 KXH65417.1 - 0.12 12.5 0.0 0.37 11.0 0.0 1.7 2 0 0 2 2 2 0 RNA recognition motif Peptidase_M1 PF01433.20 KXH65418.1 - 4e-36 124.6 0.2 6.7e-36 123.9 0.2 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 KXH65418.1 - 4.8e-30 103.9 0.0 1.1e-29 102.8 0.0 1.6 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M20 PF01546.28 KXH65418.1 - 9.6e-30 103.8 0.0 6.5e-29 101.1 0.0 2.0 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KXH65418.1 - 4.3e-10 39.5 0.0 9.7e-10 38.3 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M1_N PF17900.1 KXH65418.1 - 0.013 15.7 0.0 0.046 13.9 0.0 1.7 1 1 0 2 2 2 0 Peptidase M1 N-terminal domain Peptidase_MA_2 PF13485.6 KXH65418.1 - 0.13 11.9 1.6 0.73 9.5 1.6 2.0 1 1 0 1 1 1 0 Peptidase MA superfamily WG_beta_rep PF14903.6 KXH65418.1 - 0.13 12.6 0.1 0.33 11.3 0.1 1.7 1 0 0 1 1 1 0 WG containing repeat Tyrosinase PF00264.20 KXH65419.1 - 8e-39 134.2 4.3 2.1e-38 132.9 2.9 2.1 1 1 0 1 1 1 1 Common central domain of tyrosinase adh_short PF00106.25 KXH65420.1 - 8.3e-30 103.7 0.0 1.2e-29 103.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXH65420.1 - 4.5e-18 65.7 0.0 6.3e-18 65.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH65420.1 - 0.014 15.3 0.0 0.059 13.3 0.0 1.8 2 0 0 2 2 2 0 KR domain Epimerase PF01370.21 KXH65420.1 - 0.019 14.4 0.1 0.075 12.5 0.1 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_2 PF03446.15 KXH65420.1 - 0.1 12.7 0.0 0.98 9.6 0.0 2.1 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Abhydrolase_1 PF00561.20 KXH65421.1 - 3.9e-24 85.7 0.0 6.2e-21 75.2 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXH65421.1 - 1.2e-13 52.2 1.8 2.6e-13 51.1 1.8 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXH65421.1 - 3.5e-07 29.8 0.0 3.7e-05 23.1 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 EHN PF06441.12 KXH65421.1 - 0.064 13.6 0.3 0.26 11.7 0.0 2.2 2 0 0 2 2 2 0 Epoxide hydrolase N terminus Cellulase PF00150.18 KXH65422.1 - 9.2e-14 51.5 0.0 1.4e-13 51.0 0.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) adh_short PF00106.25 KXH65423.1 - 9.5e-29 100.2 0.1 1.3e-28 99.8 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXH65423.1 - 5.6e-20 71.9 0.1 7.4e-20 71.5 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXH65423.1 - 0.0005 20.0 0.1 0.0011 18.9 0.1 1.6 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KXH65423.1 - 0.0088 15.9 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ArfA PF03889.13 KXH65423.1 - 2.5 7.7 4.6 0.54 9.8 0.3 2.1 2 0 0 2 2 2 0 Alternative ribosome-rescue factor A Fructosamin_kin PF03881.14 KXH65424.1 - 4.9e-23 81.7 0.0 7.9e-23 81.1 0.0 1.3 1 1 0 1 1 1 1 Fructosamine kinase ANAPC4_WD40 PF12894.7 KXH65425.1 - 1.1e-09 38.4 0.0 0.029 14.6 0.0 5.3 2 1 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain NACHT PF05729.12 KXH65425.1 - 6.7e-09 35.9 0.1 2.4e-08 34.1 0.0 2.0 2 0 0 2 2 2 1 NACHT domain PGAP1 PF07819.13 KXH65425.1 - 1.4e-08 34.8 0.0 4.1e-08 33.2 0.0 1.7 2 0 0 2 2 2 1 PGAP1-like protein Abhydrolase_1 PF00561.20 KXH65425.1 - 1.3e-05 24.9 0.5 4.7e-05 23.2 0.1 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXH65425.1 - 3.5e-05 24.5 1.3 4.9e-05 24.0 0.1 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF676 PF05057.14 KXH65425.1 - 0.0044 16.6 0.0 0.0096 15.4 0.0 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) WD40 PF00400.32 KXH65425.1 - 0.033 15.1 2.5 3.2 8.8 0.0 4.8 5 0 0 5 5 3 0 WD domain, G-beta repeat AAA_7 PF12775.7 KXH65425.1 - 0.039 13.5 0.0 0.07 12.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA PF00004.29 KXH65425.1 - 0.079 13.4 0.0 0.23 11.9 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KXH65425.1 - 0.086 13.2 0.0 0.23 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.6 KXH65425.1 - 0.093 13.1 0.0 0.26 11.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain Hydrolase_4 PF12146.8 KXH65425.1 - 0.15 11.3 0.0 0.3 10.3 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 TelA PF05816.11 KXH65425.1 - 0.17 10.9 0.0 0.3 10.1 0.0 1.2 1 0 0 1 1 1 0 Toxic anion resistance protein (TelA) MFS_1 PF07690.16 KXH65426.1 - 1.5e-45 155.7 27.5 9.8e-41 139.8 10.8 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXH65426.1 - 8.9e-11 41.3 5.8 8.9e-11 41.3 5.8 2.0 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KXH65426.1 - 7.7e-08 31.2 1.1 7.7e-08 31.2 1.1 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF1640 PF07798.11 KXH65440.1 - 0.47 10.5 3.3 0.32 11.0 1.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) Peptidase_S10 PF00450.22 KXH65441.1 - 2.1e-74 251.4 0.1 3.7e-74 250.6 0.1 1.3 1 1 0 1 1 1 1 Serine carboxypeptidase Fapy_DNA_glyco PF01149.24 KXH65442.1 - 4.3e-30 104.7 0.0 9.6e-30 103.6 0.0 1.6 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.14 KXH65442.1 - 2.8e-20 72.1 0.0 5.9e-20 71.1 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain FbpA PF05833.11 KXH65442.1 - 0.015 14.0 0.0 0.028 13.2 0.0 1.3 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) Cupin_2 PF07883.11 KXH65443.1 - 1.1e-13 50.6 0.0 1.8e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 KXH65443.1 - 3.9e-06 26.6 0.0 5.1e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.19 KXH65443.1 - 0.00038 20.4 0.0 0.00054 19.9 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain CENP-C_C PF11699.8 KXH65443.1 - 0.0054 16.9 0.0 0.0083 16.3 0.0 1.3 1 0 0 1 1 1 1 Mif2/CENP-C like MannoseP_isomer PF01050.18 KXH65443.1 - 0.012 15.6 0.0 0.015 15.2 0.0 1.2 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase Cupin_6 PF12852.7 KXH65443.1 - 0.029 14.1 0.0 0.037 13.8 0.0 1.2 1 0 0 1 1 1 0 Cupin PAS_9 PF13426.7 KXH65444.1 - 3.5e-15 56.1 0.0 5.1e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 KXH65444.1 - 0.00088 19.3 0.0 0.028 14.4 0.0 2.1 1 1 0 1 1 1 1 PAS fold PAS_3 PF08447.12 KXH65444.1 - 0.018 15.3 0.0 3.2 8.1 0.0 2.7 3 0 0 3 3 3 0 PAS fold Putative_PNPOx PF01243.20 KXH65445.1 - 0.0075 16.4 0.0 1.7 8.9 0.0 2.7 2 1 0 2 2 2 2 Pyridoxamine 5'-phosphate oxidase FAD_binding_6 PF00970.24 KXH65445.1 - 0.0076 16.6 0.0 0.43 11.0 0.0 2.4 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain KCH PF16944.5 KXH65446.1 - 1e-100 336.7 9.6 1.2e-100 336.4 9.6 1.1 1 0 0 1 1 1 1 Fungal potassium channel Pkinase PF00069.25 KXH65447.1 - 0.00096 18.6 0.0 1.3 8.3 0.0 2.4 3 0 0 3 3 3 2 Protein kinase domain DUF3439 PF11921.8 KXH65451.1 - 0.25 11.3 6.8 0.36 10.8 6.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) MFS_1 PF07690.16 KXH65452.1 - 5.7e-41 140.6 52.4 3.3e-40 138.1 50.5 2.4 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KXH65452.1 - 2.2e-13 49.5 26.8 3.4e-13 48.9 26.8 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF5535 PF17687.1 KXH65453.1 - 0.23 11.6 3.0 0.86 9.8 0.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5535) Abhydrolase_6 PF12697.7 KXH65454.1 - 6.3e-11 43.3 9.1 3.5e-10 40.9 9.1 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXH65454.1 - 0.00012 21.4 0.0 0.00022 20.6 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KXH65454.1 - 0.0038 16.9 0.0 0.0068 16.1 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 KXH65454.1 - 0.18 10.7 0.0 0.29 10.0 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Peptidase_S9 PF00326.21 KXH65454.1 - 0.19 11.2 0.0 0.46 9.9 0.0 1.6 2 0 0 2 2 2 0 Prolyl oligopeptidase family Gryzun PF07919.12 KXH65455.1 - 1.6e-239 796.7 0.0 1.9e-239 796.4 0.0 1.1 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi Foie-gras_1 PF11817.8 KXH65455.1 - 2.4e-94 315.8 7.0 4.4e-88 295.2 5.4 2.2 2 0 0 2 2 2 2 Foie gras liver health family 1 Gryzun-like PF12742.7 KXH65455.1 - 0.00026 20.9 0.0 0.00061 19.7 0.0 1.7 1 0 0 1 1 1 1 Gryzun, putative Golgi trafficking RXT2_N PF08595.11 KXH65456.1 - 3.6e-43 147.3 0.0 3.6e-43 147.3 0.0 3.1 3 1 0 3 3 3 1 RXT2-like, N-terminal cNMPbd_u2 PF16643.5 KXH65456.1 - 0.22 12.0 5.8 1.8 9.0 0.2 2.6 1 1 1 2 2 2 0 Unstructured region on cNMP-binding protein PEMT PF04191.13 KXH65457.1 - 5.8e-34 116.7 2.8 1.2e-33 115.7 2.8 1.4 1 0 0 1 1 1 1 Phospholipid methyltransferase Nramp PF01566.18 KXH65458.1 - 3.2e-80 269.8 28.0 3.2e-80 269.8 28.0 2.5 2 1 0 2 2 2 1 Natural resistance-associated macrophage protein DUF5466 PF17554.2 KXH65458.1 - 0.18 12.0 1.8 16 5.8 0.1 3.0 2 0 0 2 2 2 0 Family of unknown function (DUF5466) # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Colletotrichum_nymphaeae_SA-01-CNYM01/GCA_001563115.1_CNYM01_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Colletotrichum_nymphaeae_SA-01-CNYM01/GCA_001563115.1_CNYM01_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Colletotrichum_nymphaeae_SA-01-CNYM01/GCA_001563115.1_CNYM01_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Colletotrichum_nymphaeae_SA-01-CNYM01/GCA_001563115.1_CNYM01_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Sun Mar 24 19:10:35 2019 # [ok]