# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- DUF2427 PF10348.9 ORX88624.1 - 0.1 12.4 0.3 0.1 12.4 0.3 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF2427) MAP17 PF15807.5 ORX88624.1 - 0.15 12.3 0.2 0.27 11.5 0.2 1.3 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Cytochrom_B561 PF03188.16 ORX88624.1 - 0.95 9.6 15.4 0.3 11.2 9.3 2.9 1 1 1 2 2 2 0 Eukaryotic cytochrome b561 CorA PF01544.18 ORX88624.1 - 5.3 6.3 5.4 3.1 7.0 3.1 1.7 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein DUF1223 PF06764.11 ORX88690.1 - 5.7e-22 78.7 0.0 6.6e-22 78.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1223) NAD_binding_10 PF13460.6 ORX88887.1 - 0.18 11.7 0.0 1.4 8.8 0.0 2.1 2 0 0 2 2 2 0 NAD(P)H-binding Bax1-I PF01027.20 ORX88908.1 - 1.1e-32 113.6 8.8 1.5e-32 113.1 8.8 1.2 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 FATC PF02260.20 ORX88908.1 - 0.013 15.3 0.1 0.032 14.1 0.1 1.6 1 0 0 1 1 1 0 FATC domain CVNH PF08881.10 ORX88909.1 - 7.6e-28 97.2 0.2 8.4e-28 97.0 0.2 1.0 1 0 0 1 1 1 1 CVNH domain ArfGap PF01412.18 ORX89203.1 - 3.1e-31 107.9 0.0 5.8e-31 107.0 0.0 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf DUF4149 PF13664.6 ORX89215.1 - 5.3e-25 87.7 5.7 2.5e-24 85.6 5.7 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4149) DUF1772 PF08592.11 ORX89215.1 - 0.0017 18.7 0.1 0.0024 18.2 0.1 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF1772) Iwr1 PF08574.10 ORX89336.1 - 5.2e-19 69.0 18.2 5.2e-19 69.0 18.2 2.4 2 0 0 2 2 2 1 Transcription factor Iwr1 ABC2_membrane PF01061.24 ORX89414.1 - 3.1e-41 141.1 28.8 3.1e-41 141.1 28.8 3.9 4 0 0 4 4 4 1 ABC-2 type transporter PDR_CDR PF06422.12 ORX89414.1 - 5.3e-38 128.8 16.7 3e-34 116.8 1.3 3.5 3 1 1 4 4 3 2 CDR ABC transporter ABC_tran PF00005.27 ORX89414.1 - 4.2e-18 66.2 0.0 7.6e-18 65.4 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ORX89414.1 - 8.3e-06 25.8 0.0 0.16 11.8 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 ORX89414.1 - 0.0001 22.7 0.0 0.00023 21.6 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 ORX89414.1 - 0.0002 21.0 0.2 0.00048 19.8 0.2 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_33 PF13671.6 ORX89414.1 - 0.00023 21.3 0.0 0.00044 20.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 ORX89414.1 - 0.00029 20.4 0.0 0.0011 18.4 0.0 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 ORX89414.1 - 0.0003 20.4 0.0 0.00066 19.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 ORX89414.1 - 0.00077 20.0 0.0 0.0016 19.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 ORX89414.1 - 0.0016 18.4 0.0 0.003 17.5 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase cobW PF02492.19 ORX89414.1 - 0.0046 16.6 0.1 0.013 15.1 0.1 1.7 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.6 ORX89414.1 - 0.015 15.8 0.2 0.06 13.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 ORX89414.1 - 0.036 14.3 0.2 0.12 12.7 0.2 2.0 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 ORX89414.1 - 0.081 13.2 0.2 0.21 11.8 0.2 1.7 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 ORX89414.1 - 0.083 12.6 0.1 0.14 11.9 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 ORX89414.1 - 0.17 12.3 0.0 0.34 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain adh_short PF00106.25 ORX89415.1 - 1.5e-34 119.2 0.0 2.1e-34 118.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORX89415.1 - 2e-20 73.4 0.1 3.9e-20 72.4 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORX89415.1 - 1.3e-05 25.2 0.3 7.4e-05 22.7 0.3 1.9 1 1 0 1 1 1 1 KR domain DUF3328 PF11807.8 ORX89431.1 - 2.8e-19 69.8 0.7 3.3e-19 69.5 0.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Glyco_hydro_11 PF00457.17 ORX89432.1 - 9.4e-61 204.5 17.0 1.1e-60 204.3 17.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 MFS_1 PF07690.16 ORX89511.1 - 3.6e-34 118.2 22.2 5.4e-34 117.7 22.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DHDPS PF00701.22 ORX89512.1 - 3.9e-36 124.2 0.0 4.6e-36 124.0 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family PA PF02225.22 ORX89512.1 - 0.057 13.4 0.1 0.12 12.5 0.1 1.5 1 0 0 1 1 1 0 PA domain Pap_E4 PF02711.14 ORX89561.1 - 5.9 7.9 8.2 0.75 10.8 0.8 2.6 2 1 0 2 2 2 0 E4 protein PIN_5 PF08745.11 ORX89685.1 - 0.086 12.3 0.0 0.099 12.1 0.0 1.1 1 0 0 1 1 1 0 PINc domain ribonuclease Pro_isomerase PF00160.21 ORX89707.1 - 4.9e-36 124.4 0.0 6.4e-36 124.0 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Glyco_hydro_43 PF04616.14 ORX89749.1 - 2.5e-69 233.8 2.7 3.2e-69 233.4 2.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 ORX89749.1 - 1.7e-18 67.1 0.0 3.2e-18 66.2 0.0 1.5 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain AAA PF00004.29 ORX89750.1 - 2.2e-35 122.0 0.0 4.3e-35 121.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 ORX89750.1 - 1.4e-21 76.3 1.1 5e-21 74.4 1.1 2.1 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_lid_3 PF17862.1 ORX89750.1 - 7.8e-07 28.8 0.0 1e-05 25.2 0.0 2.4 2 0 0 2 2 2 1 AAA+ lid domain AAA_16 PF13191.6 ORX89750.1 - 2.6e-06 27.9 0.2 0.00097 19.6 0.0 2.6 1 1 1 2 2 2 1 AAA ATPase domain DUF815 PF05673.13 ORX89750.1 - 3e-05 23.3 0.0 0.0032 16.7 0.0 2.5 1 1 1 2 2 2 2 Protein of unknown function (DUF815) AAA_5 PF07728.14 ORX89750.1 - 6.9e-05 22.9 0.0 0.00052 20.0 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 ORX89750.1 - 7.6e-05 22.5 0.0 0.00022 21.0 0.0 1.8 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 ORX89750.1 - 0.00014 22.2 0.1 0.0014 18.9 0.1 2.2 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 ORX89750.1 - 0.00015 21.5 0.0 0.00036 20.3 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 ORX89750.1 - 0.00037 21.1 0.0 0.0014 19.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 ORX89750.1 - 0.00038 20.7 0.0 0.00092 19.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 ORX89750.1 - 0.002 18.5 0.0 0.0052 17.2 0.0 1.8 1 0 0 1 1 1 1 RNA helicase Parvo_NS1 PF01057.17 ORX89750.1 - 0.0025 16.9 0.0 0.0043 16.2 0.0 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 TIP49 PF06068.13 ORX89750.1 - 0.0026 17.0 0.0 0.0044 16.3 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_24 PF13479.6 ORX89750.1 - 0.0044 16.8 0.0 0.0076 16.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 ORX89750.1 - 0.0051 16.5 0.0 0.014 15.2 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 ORX89750.1 - 0.006 16.1 0.0 0.021 14.3 0.0 2.0 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_14 PF13173.6 ORX89750.1 - 0.0078 16.2 0.0 0.019 15.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 ORX89750.1 - 0.0083 16.6 0.0 0.042 14.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.14 ORX89750.1 - 0.012 15.7 0.0 0.035 14.2 0.0 1.8 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_25 PF13481.6 ORX89750.1 - 0.013 15.1 0.2 0.12 12.0 0.0 2.3 1 1 1 2 2 2 0 AAA domain Mg_chelatase PF01078.21 ORX89750.1 - 0.014 14.8 0.0 0.046 13.1 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ATPase PF06745.13 ORX89750.1 - 0.02 14.2 0.2 0.57 9.5 0.0 2.4 2 1 1 3 3 3 0 KaiC Torsin PF06309.11 ORX89750.1 - 0.039 14.0 0.0 0.076 13.1 0.0 1.4 1 0 0 1 1 1 0 Torsin ABC_tran PF00005.27 ORX89750.1 - 0.058 13.9 0.0 0.23 12.0 0.0 2.0 2 0 0 2 2 2 0 ABC transporter ATPase_2 PF01637.18 ORX89750.1 - 0.088 12.7 0.1 2.8 7.8 0.0 2.5 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea PhoH PF02562.16 ORX89750.1 - 0.089 12.2 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein Cytidylate_kin PF02224.18 ORX89750.1 - 0.12 12.1 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 Cytidylate kinase Yae1_N PF09811.9 ORX89751.1 - 7.5e-13 47.9 4.9 1.4e-12 47.1 4.9 1.5 1 0 0 1 1 1 1 Essential protein Yae1, N terminal Ank_2 PF12796.7 ORX89855.1 - 1.1e-15 57.9 0.1 1.5e-06 28.7 0.0 3.8 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORX89855.1 - 4.5e-07 30.3 1.1 0.00062 20.3 0.0 4.5 4 2 1 5 5 5 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 ORX89855.1 - 7.2e-07 29.4 0.3 0.00012 22.3 0.0 3.7 3 1 1 4 4 4 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORX89855.1 - 1.5e-05 25.0 2.4 74 4.4 0.0 6.5 6 0 0 6 6 6 0 Ankyrin repeat Ank PF00023.30 ORX89855.1 - 8.9e-05 22.8 9.8 0.6 10.7 0.2 5.6 4 2 0 4 4 4 2 Ankyrin repeat DUF1751 PF08551.10 ORX89857.1 - 6.5e-28 97.2 3.2 1.3e-27 96.2 3.2 1.5 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.22 ORX89857.1 - 3 7.8 11.2 8.6 6.3 11.1 1.8 1 1 0 1 1 1 0 Rhomboid family WD40 PF00400.32 ORX89858.1 - 3.3e-07 30.9 0.8 2.1 9.3 0.0 4.8 5 0 0 5 5 5 3 WD domain, G-beta repeat LisH PF08513.11 ORX89858.1 - 0.00014 21.7 0.1 0.00035 20.4 0.1 1.7 1 0 0 1 1 1 1 LisH PD40 PF07676.12 ORX89858.1 - 0.015 15.2 0.2 1.6 8.7 0.0 2.8 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat eIF2A PF08662.11 ORX89858.1 - 0.07 13.0 0.0 1.2 9.0 0.0 2.3 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Collagen PF01391.18 ORX89913.1 - 0.00055 19.6 0.7 0.0024 17.6 0.3 2.1 3 0 0 3 3 3 1 Collagen triple helix repeat (20 copies) MFS_1 PF07690.16 ORX89937.1 - 5.3e-35 121.0 35.4 5.3e-35 121.0 35.4 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORX89937.1 - 2.2e-10 40.0 8.6 2.2e-10 40.0 8.6 1.6 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 ORX89937.1 - 1.6e-05 23.6 2.9 2.2e-05 23.1 2.9 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) p450 PF00067.22 ORX89938.1 - 3.2e-50 171.2 0.0 4e-50 170.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Zn_clus PF00172.18 ORX89940.1 - 3.6e-08 33.4 10.2 7.9e-08 32.3 10.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2039 PF10217.9 ORX89940.1 - 0.13 12.6 4.7 0.23 11.8 4.7 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) Anticodon_1 PF08264.13 ORX89940.1 - 0.14 12.1 0.0 0.37 10.7 0.0 1.6 1 0 0 1 1 1 0 Anticodon-binding domain of tRNA PsbJ PF01788.17 ORX89940.1 - 0.18 11.7 1.4 0.35 10.8 1.4 1.4 1 0 0 1 1 1 0 PsbJ Cu-oxidase_3 PF07732.15 ORX89963.1 - 2.5e-43 146.8 1.6 2.5e-43 146.8 1.6 3.0 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 ORX89963.1 - 1.5e-38 131.6 9.3 1.8e-33 115.2 0.5 3.8 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 ORX89963.1 - 4.1e-31 108.3 0.2 1.1e-30 106.9 0.2 1.7 1 0 0 1 1 1 1 Multicopper oxidase fn3 PF00041.21 ORX89963.1 - 0.096 13.0 1.7 5.4 7.4 0.0 3.5 3 0 0 3 3 3 0 Fibronectin type III domain Glyco_hydro_39 PF01229.17 ORX90079.1 - 4.6e-28 98.1 0.0 2.4e-21 75.9 0.0 2.3 1 1 1 2 2 2 2 Glycosyl hydrolases family 39 RhoGAP PF00620.27 ORX90080.1 - 2.1e-39 134.8 0.1 4.3e-39 133.8 0.1 1.5 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.29 ORX90080.1 - 6e-14 52.4 0.0 1.8e-13 50.9 0.0 1.9 2 0 0 2 2 2 1 PH domain PH_11 PF15413.6 ORX90080.1 - 0.00056 20.3 1.0 0.00088 19.7 0.0 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.6 ORX90080.1 - 0.11 12.7 0.1 0.75 10.1 0.0 2.2 2 0 0 2 2 2 0 Pleckstrin homology domain F-box_4 PF15966.5 ORX90193.1 - 0.0076 16.1 0.0 0.022 14.6 0.0 1.8 2 0 0 2 2 2 1 F-box PAF-AH_p_II PF03403.13 ORX90194.1 - 2.7e-31 108.4 0.0 1.8e-29 102.4 0.0 2.1 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 ORX90194.1 - 5.9e-11 41.8 0.0 1.4e-10 40.5 0.0 1.6 1 1 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 ORX90194.1 - 8.4e-07 28.3 0.5 0.00031 19.9 0.0 2.6 3 0 0 3 3 3 2 Chlorophyllase Hydrolase_4 PF12146.8 ORX90194.1 - 2.8e-05 23.5 2.4 0.0082 15.4 0.9 2.4 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ORX90194.1 - 0.013 16.1 2.8 0.013 16.1 2.8 2.3 2 1 0 2 2 2 0 Alpha/beta hydrolase family PPR PF01535.20 ORX90194.1 - 0.24 11.7 0.3 0.62 10.4 0.3 1.7 1 0 0 1 1 1 0 PPR repeat GST_N_2 PF13409.6 ORX90195.1 - 3.5e-20 72.1 0.0 6.3e-20 71.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 ORX90195.1 - 6.1e-16 58.2 0.0 1.3e-15 57.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 ORX90195.1 - 3.3e-05 24.0 0.0 6e-05 23.2 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 ORX90195.1 - 0.00082 19.5 0.0 0.0036 17.5 0.0 2.1 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 ORX90195.1 - 0.0021 18.4 0.0 0.02 15.3 0.0 2.1 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Blt1 PF12754.7 ORX90261.1 - 6.7e-45 153.1 0.2 7.7e-45 152.9 0.2 1.0 1 0 0 1 1 1 1 Blt1 N-terminal domain ubiquitin PF00240.23 ORX90261.1 - 4.9e-05 23.0 0.0 6.5e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 ORX90261.1 - 0.041 13.7 0.0 0.064 13.1 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Methyltr_RsmB-F PF01189.17 ORX90262.1 - 2.6e-77 259.0 0.0 4.2e-77 258.3 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 ORX90262.1 - 3.5e-09 37.0 0.0 8.7e-09 35.8 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of 16S rRNA methyltransferase RsmF Met_10 PF02475.16 ORX90262.1 - 0.016 15.0 0.0 0.03 14.1 0.0 1.4 1 0 0 1 1 1 0 Met-10+ like-protein Flg_new PF09479.10 ORX90262.1 - 0.024 14.8 0.4 0.071 13.3 0.4 1.8 1 0 0 1 1 1 0 Listeria-Bacteroides repeat domain (List_Bact_rpt) FtsJ PF01728.19 ORX90262.1 - 0.036 14.2 0.3 0.12 12.5 0.0 1.9 2 0 0 2 2 2 0 FtsJ-like methyltransferase DUF2431 PF10354.9 ORX90262.1 - 0.11 12.8 0.0 0.18 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2431) DUF4717 PF15838.5 ORX90262.1 - 0.56 10.2 4.0 0.87 9.6 1.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4717) PGC7_Stella PF15549.6 ORX90263.1 - 0.079 13.0 2.1 0.11 12.5 2.1 1.1 1 0 0 1 1 1 0 PGC7/Stella/Dppa3 domain TT_ORF1 PF02956.14 ORX90263.1 - 6.1 5.4 7.2 7.8 5.0 7.2 1.1 1 0 0 1 1 1 0 TT viral orf 1 Sugar_tr PF00083.24 ORX90264.1 - 6.1e-124 414.3 24.0 7.2e-124 414.1 24.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORX90264.1 - 7.1e-19 67.9 35.2 2.1e-18 66.4 30.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Ilm1 PF10311.9 ORX90264.1 - 0.057 13.1 1.0 0.11 12.2 1.0 1.4 1 0 0 1 1 1 0 Increased loss of mitochondrial DNA protein 1 MSP1b PF03429.13 ORX90264.1 - 0.19 9.8 0.3 0.26 9.3 0.3 1.1 1 0 0 1 1 1 0 Major surface protein 1B MBOAT PF03062.19 ORX90265.1 - 9.4e-50 169.9 5.1 1.7e-49 169.1 5.1 1.4 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family DUF3405 PF11885.8 ORX90489.1 - 4.6e-180 599.6 10.7 6e-180 599.2 10.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) Glyco_transf_34 PF05637.12 ORX90489.1 - 0.19 11.4 2.7 0.31 10.7 2.7 1.3 1 0 0 1 1 1 0 galactosyl transferase GMA12/MNN10 family ArabFuran-catal PF09206.11 ORX90505.1 - 9.7e-150 498.2 12.6 1.3e-149 497.8 12.6 1.2 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B, catalytic AbfB PF05270.13 ORX90505.1 - 3.2e-48 163.3 3.0 4.9e-48 162.7 3.0 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B (ABFB) domain DUF4387 PF14330.6 ORX90663.1 - 6.1e-36 123.0 0.0 7.2e-36 122.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4387) Methyltransf_2 PF00891.18 ORX90665.1 - 6.5e-11 41.9 0.2 1.9e-10 40.4 0.2 1.8 1 1 0 1 1 1 1 O-methyltransferase domain Dimerisation PF08100.11 ORX90665.1 - 0.11 12.6 0.7 0.27 11.3 0.1 2.1 2 0 0 2 2 2 0 Dimerisation domain DPBB_1 PF03330.18 ORX90666.1 - 1.4e-08 34.9 0.4 8.3e-08 32.4 0.1 2.5 2 1 0 2 2 2 1 Lytic transglycolase Barwin PF00967.17 ORX90666.1 - 0.0077 16.1 0.1 0.018 14.9 0.1 1.6 1 0 0 1 1 1 1 Barwin family Pollen_allerg_1 PF01357.21 ORX90666.1 - 0.024 14.6 0.6 0.056 13.5 0.6 1.6 1 0 0 1 1 1 0 Pollen allergen Amidase PF01425.21 ORX90686.1 - 1e-45 156.6 3.1 3.8e-25 88.8 0.0 2.6 1 1 1 2 2 2 2 Amidase Glutaredoxin PF00462.24 ORX90686.1 - 0.22 11.8 1.0 24 5.2 0.1 3.3 4 0 0 4 4 4 0 Glutaredoxin PUD1_2 PF18457.1 ORX90687.1 - 2.2e-63 213.4 2.1 2.5e-63 213.2 2.1 1.0 1 0 0 1 1 1 1 Up-Regulated in long-lived daf-2 Aminotran_1_2 PF00155.21 ORX90706.1 - 8.9e-07 28.4 0.0 9.6e-07 28.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aquarius_N PF16399.5 ORX90723.1 - 0 1090.6 0.0 0 1090.3 0.0 1.1 1 0 0 1 1 1 1 Intron-binding protein aquarius N-terminus AAA_11 PF13086.6 ORX90723.1 - 8.1e-22 78.3 0.0 1.2e-20 74.4 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_12 PF13087.6 ORX90723.1 - 6.2e-12 45.6 0.0 9.6e-12 44.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 ORX90723.1 - 9.4e-07 28.7 0.0 0.00039 20.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 ORX90723.1 - 1.5e-05 25.4 0.0 3e-05 24.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 ORX90723.1 - 2.2e-05 24.5 0.0 4.5e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_16 PF13191.6 ORX90723.1 - 0.0011 19.4 0.4 0.0053 17.2 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain DnaB_C PF03796.15 ORX90723.1 - 0.0016 17.9 0.0 0.0027 17.1 0.0 1.3 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA PF00004.29 ORX90723.1 - 0.0062 17.0 0.0 0.014 15.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.9 ORX90723.1 - 0.012 14.9 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DEAD PF00270.29 ORX90723.1 - 0.025 14.3 0.0 0.048 13.4 0.0 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA_22 PF13401.6 ORX90723.1 - 0.028 14.7 1.7 0.27 11.5 0.2 2.9 2 1 1 3 3 3 0 AAA domain AAA_33 PF13671.6 ORX90723.1 - 0.055 13.6 0.0 0.47 10.6 0.0 2.6 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 ORX90723.1 - 0.065 13.2 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Parvo_NS1 PF01057.17 ORX90723.1 - 0.1 11.7 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 UvrD-helicase PF00580.21 ORX90723.1 - 0.17 11.4 0.0 0.38 10.2 0.0 1.6 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain NADH-u_ox-rdase PF10785.9 ORX90724.1 - 1.1e-29 102.9 0.5 3.7e-29 101.2 0.1 2.0 2 1 1 3 3 3 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH_u_ox_C PF12853.7 ORX90724.1 - 8.6e-26 89.8 0.0 1.3e-25 89.2 0.0 1.3 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit Tfb2 PF03849.14 ORX90725.1 - 3.4e-129 430.9 0.5 4e-129 430.6 0.5 1.1 1 0 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 ORX90725.1 - 3.1e-19 69.2 0.1 6.3e-19 68.2 0.1 1.6 1 0 0 1 1 1 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 ORX90725.1 - 0.0076 16.4 0.1 0.095 12.8 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain 4HBT PF03061.22 ORX90726.1 - 1.7e-14 53.9 0.1 2.7e-14 53.3 0.1 1.3 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.6 ORX90726.1 - 0.074 13.2 0.0 0.092 12.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) PBECR2 PF18810.1 ORX90726.1 - 0.15 12.4 0.0 0.23 11.7 0.0 1.3 1 0 0 1 1 1 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease2 MFS_1 PF07690.16 ORX90761.1 - 0.013 14.5 6.8 0.018 14.0 6.9 1.3 1 1 0 1 1 1 0 Major Facilitator Superfamily SYS1 PF09801.9 ORX90761.1 - 0.12 12.6 0.0 0.15 12.2 0.0 1.2 1 0 0 1 1 1 0 Integral membrane protein S linking to the trans Golgi network F-box-like PF12937.7 ORX90762.1 - 6.3e-05 22.8 0.1 0.00013 21.8 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORX90762.1 - 0.17 11.8 2.5 0.55 10.2 2.5 1.9 1 1 0 1 1 1 0 F-box domain PTR2 PF00854.21 ORX90763.1 - 1.8e-67 227.9 5.6 6.5e-67 226.1 5.5 1.8 1 1 0 1 1 1 1 POT family Aminotran_1_2 PF00155.21 ORX90764.1 - 1.3e-36 126.5 0.0 1.6e-36 126.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II HET PF06985.11 ORX90920.1 - 3.3e-22 79.4 0.0 5.5e-22 78.7 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF1793 PF08760.11 ORX90922.1 - 6.4e-71 238.2 0.0 1.4e-70 237.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) DUF4965 PF16335.5 ORX90922.1 - 3.7e-63 212.3 1.3 6.7e-50 169.1 0.1 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4965) DUF5127 PF17168.4 ORX90922.1 - 3.5e-42 144.8 0.1 5.7e-42 144.0 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF4964 PF16334.5 ORX90922.1 - 0.00017 21.1 0.0 0.00047 19.6 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4964) zf-CCHC PF00098.23 ORX90924.1 - 3.1e-10 39.6 7.6 0.00011 22.2 1.4 2.3 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_3 PF13917.6 ORX90924.1 - 0.006 16.5 3.8 0.15 12.1 0.1 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_5 PF14787.6 ORX90924.1 - 0.01 15.5 6.0 0.5 10.1 0.2 2.4 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger CFEM PF05730.11 ORX90945.1 - 0.023 14.8 3.7 0.054 13.6 3.7 1.7 1 1 0 1 1 1 0 CFEM domain Pyr_redox_2 PF07992.14 ORX90946.1 - 0.057 12.6 0.0 0.061 12.5 0.0 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase VKG_Carbox PF05090.14 ORX90973.1 - 0.13 11.1 0.0 0.15 10.9 0.0 1.1 1 0 0 1 1 1 0 Vitamin K-dependent gamma-carboxylase DEAD PF00270.29 ORX90974.1 - 3.5e-41 140.9 0.2 5.4e-41 140.3 0.2 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORX90974.1 - 9.3e-20 71.0 0.1 1.2e-18 67.5 0.0 2.7 4 0 0 4 4 4 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORX90974.1 - 4.5e-06 26.8 0.0 6.9e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit RNA_polI_A34 PF08208.11 ORX90975.1 - 0.012 15.8 33.4 0.023 14.8 33.4 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 DDHD PF02862.17 ORX90975.1 - 0.41 10.8 6.3 0.29 11.3 4.0 2.0 2 0 0 2 2 2 0 DDHD domain DUF2201_N PF13203.6 ORX90975.1 - 3.5 7.1 12.8 5.8 6.4 12.8 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain RNA_pol_Rpc4 PF05132.14 ORX90975.1 - 4.7 7.6 17.5 10 6.5 17.5 1.6 1 0 0 1 1 1 0 RNA polymerase III RPC4 Rtf2 PF04641.12 ORX90975.1 - 7.4 5.9 26.5 13 5.1 26.5 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger DUF1682 PF07946.14 ORX90975.1 - 8.5 5.5 34.9 14 4.8 34.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Ank_4 PF13637.6 ORX91011.1 - 1e-10 41.9 0.1 2.9e-10 40.5 0.1 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 ORX91011.1 - 1.8e-09 37.7 0.1 1.3e-06 28.5 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 ORX91011.1 - 2.3e-09 37.7 0.1 5.2e-09 36.6 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ORX91011.1 - 1.6e-07 31.1 0.0 0.0025 18.2 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 ORX91011.1 - 1.1e-05 25.6 0.1 0.00018 21.8 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeat SesA PF17107.5 ORX91011.1 - 0.0058 16.8 1.3 0.014 15.6 0.6 2.0 2 0 0 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases Helo_like_N PF17111.5 ORX91011.1 - 0.0078 15.6 0.9 0.017 14.5 0.5 1.8 2 0 0 2 2 2 1 Fungal N-terminal domain of STAND proteins Ku_C PF03730.14 ORX91011.1 - 0.039 14.6 3.1 0.089 13.5 1.2 2.3 2 0 0 2 2 2 0 Ku70/Ku80 C-terminal arm Glyco_hydro_43 PF04616.14 ORX91012.1 - 2.2e-70 237.3 4.6 2.8e-70 236.9 4.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 ORX91012.1 - 1.1e-08 35.1 0.0 1.7e-07 31.1 0.0 2.1 1 1 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain PD40 PF07676.12 ORX91012.1 - 0.01 15.8 1.1 0.039 13.9 1.1 2.0 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat CAP59_mtransfer PF11735.8 ORX91025.1 - 3.3e-66 223.4 0.0 4.5e-66 223.0 0.0 1.2 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 TMEM154 PF15102.6 ORX91026.1 - 0.0026 17.7 3.0 0.014 15.3 3.0 1.9 1 1 0 1 1 1 1 TMEM154 protein family SPX PF03105.19 ORX91026.1 - 0.0098 15.9 0.5 0.0098 15.9 0.5 1.1 1 0 0 1 1 1 1 SPX domain Adeno_E3_CR2 PF02439.15 ORX91026.1 - 0.023 14.5 0.1 0.034 13.9 0.1 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Neisseria_TspB PF05616.13 ORX91026.1 - 0.049 12.1 0.6 0.066 11.7 0.6 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein SKG6 PF08693.10 ORX91026.1 - 0.078 12.4 0.2 0.17 11.3 0.2 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain TrbC PF04956.13 ORX91026.1 - 0.13 12.5 1.0 0.22 11.7 0.1 1.7 2 0 0 2 2 2 0 TrbC/VIRB2 family DUF1180 PF06679.12 ORX91026.1 - 0.17 12.3 6.6 0.28 11.6 6.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Syndecan PF01034.20 ORX91026.1 - 0.26 11.2 0.2 0.46 10.4 0.2 1.3 1 0 0 1 1 1 0 Syndecan domain Carb_bind PF10645.9 ORX91026.1 - 0.36 11.1 2.9 1.1 9.5 2.9 1.8 1 0 0 1 1 1 0 Carbohydrate binding Macoilin PF09726.9 ORX91026.1 - 0.64 8.5 4.7 0.78 8.2 4.7 1.1 1 0 0 1 1 1 0 Macoilin family Apt1 PF10351.9 ORX91026.1 - 0.83 8.4 2.2 0.97 8.2 2.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain BUD22 PF09073.10 ORX91026.1 - 3.6 6.8 6.8 4.5 6.5 6.8 1.1 1 0 0 1 1 1 0 BUD22 Mito_fiss_reg PF05308.11 ORX91026.1 - 6.8 6.7 9.8 9.8 6.2 9.8 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator MSA-2c PF12238.8 ORX91026.1 - 7.9 6.4 11.3 13 5.7 11.3 1.4 1 0 0 1 1 1 0 Merozoite surface antigen 2c DUF2183 PF09949.9 ORX91065.1 - 3e-21 75.6 0.0 5.6e-21 74.7 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) P5CR_dimer PF14748.6 ORX91106.1 - 7.9e-30 103.2 2.0 1.8e-29 102.0 2.0 1.6 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 ORX91106.1 - 3.8e-07 30.6 0.3 3e-06 27.7 0.3 2.3 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Amidase PF01425.21 ORX91107.1 - 1.2e-30 106.9 0.0 1.8e-30 106.3 0.0 1.2 1 0 0 1 1 1 1 Amidase SAP PF02037.27 ORX91107.1 - 0.19 11.5 0.0 0.49 10.2 0.0 1.7 2 0 0 2 2 2 0 SAP domain Thioesterase PF00975.20 ORX91109.1 - 1.7e-13 51.3 0.0 1.1e-11 45.3 0.0 2.1 2 0 0 2 2 2 2 Thioesterase domain Abhydrolase_6 PF12697.7 ORX91109.1 - 4.4e-06 27.4 0.4 5.4e-06 27.2 0.4 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 ORX91109.1 - 0.086 12.7 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ORX91109.1 - 0.1 11.8 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 ABC_membrane PF00664.23 ORX91110.1 - 4.9e-81 272.4 37.3 7.7e-41 140.5 13.6 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 ORX91110.1 - 1.6e-66 223.0 0.0 2.3e-33 115.6 0.0 3.4 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 ORX91110.1 - 5.8e-12 45.5 0.3 0.00095 18.7 0.3 4.0 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 ORX91110.1 - 2.7e-09 37.2 0.0 0.00097 19.1 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 ORX91110.1 - 5.6e-09 36.4 0.5 0.017 15.4 0.0 3.9 3 1 0 3 3 3 2 AAA domain AAA_16 PF13191.6 ORX91110.1 - 2e-07 31.5 0.1 0.13 12.6 0.0 3.6 3 0 0 3 3 3 2 AAA ATPase domain AAA_15 PF13175.6 ORX91110.1 - 7.4e-07 29.2 0.4 0.016 15.0 0.1 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 ORX91110.1 - 8e-07 28.7 0.3 0.015 15.0 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 ORX91110.1 - 2.2e-05 25.0 4.9 0.11 12.9 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_30 PF13604.6 ORX91110.1 - 0.00016 21.5 0.0 0.82 9.4 0.0 3.3 4 0 0 4 4 4 2 AAA domain Rad17 PF03215.15 ORX91110.1 - 0.00024 21.1 0.0 0.18 11.7 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain AAA PF00004.29 ORX91110.1 - 0.00031 21.2 0.1 0.88 10.0 0.0 3.9 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 ORX91110.1 - 0.00048 20.3 0.0 1.6 8.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 ORX91110.1 - 0.0007 19.2 0.0 0.52 9.8 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_21 PF13304.6 ORX91110.1 - 0.00089 19.2 0.9 0.21 11.4 0.1 3.4 2 2 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 ORX91110.1 - 0.001 18.7 0.0 1.8 8.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 ORX91110.1 - 0.0011 19.2 0.5 0.55 10.5 0.1 3.1 3 0 0 3 3 3 1 AAA domain AAA_5 PF07728.14 ORX91110.1 - 0.0017 18.4 0.0 1.4 8.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 ORX91110.1 - 0.0039 16.4 0.0 0.62 9.2 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain AAA_18 PF13238.6 ORX91110.1 - 0.0049 17.4 1.3 0.87 10.1 0.0 3.3 3 0 0 3 3 2 1 AAA domain MMR_HSR1 PF01926.23 ORX91110.1 - 0.0053 16.8 0.1 1.8 8.7 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase ATP-synt_ab PF00006.25 ORX91110.1 - 0.0074 16.0 0.0 2.9 7.5 0.0 2.5 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain SRP54 PF00448.22 ORX91110.1 - 0.0079 15.8 0.0 2 8.0 0.0 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain IstB_IS21 PF01695.17 ORX91110.1 - 0.019 14.7 0.0 14 5.4 0.0 3.2 3 0 0 3 3 3 0 IstB-like ATP binding protein RNA_helicase PF00910.22 ORX91110.1 - 0.02 15.3 0.0 8 6.9 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_17 PF13207.6 ORX91110.1 - 0.026 14.9 0.0 1.9 8.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain PRK PF00485.18 ORX91110.1 - 0.048 13.4 0.1 8 6.1 0.0 2.6 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family dNK PF01712.19 ORX91110.1 - 0.17 11.7 0.0 11 5.9 0.0 2.3 2 0 0 2 2 2 0 Deoxynucleoside kinase G-alpha PF00503.20 ORX91110.1 - 0.19 10.8 0.0 20 4.2 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit SbcCD_C PF13558.6 ORX91110.1 - 0.27 11.5 7.7 1.7 9.0 0.1 4.1 3 2 0 3 3 2 0 Putative exonuclease SbcCD, C subunit DUF4470 PF14737.6 ORX91138.1 - 6.8e-15 55.0 0.0 3e-14 53.0 0.0 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF4470) T5orf172 PF10544.9 ORX91140.1 - 7.2e-08 32.9 4.0 2.3e-07 31.3 0.5 2.3 1 1 1 2 2 2 1 T5orf172 domain MUG113 PF13455.6 ORX91140.1 - 1.3e-07 32.1 0.1 1.9e-07 31.7 0.1 1.3 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 UPRTase PF14681.6 ORX91186.1 - 1.7e-80 269.4 0.0 2.2e-80 269.0 0.0 1.1 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 ORX91186.1 - 0.0024 17.4 0.0 0.0035 16.9 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Elf1 PF05129.13 ORX91187.1 - 1.1e-29 102.3 1.0 1.1e-29 102.3 1.0 1.6 2 0 0 2 2 2 1 Transcription elongation factor Elf1 like Zn-ribbon_8 PF09723.10 ORX91187.1 - 0.038 14.1 0.2 0.089 12.9 0.2 1.7 1 0 0 1 1 1 0 Zinc ribbon domain TF_Zn_Ribbon PF08271.12 ORX91187.1 - 0.12 11.9 0.4 0.28 10.7 0.4 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding GTP_CH_N PF12471.8 ORX91188.1 - 8.6e-91 302.9 0.0 1.2e-90 302.4 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.20 ORX91188.1 - 3.2e-17 62.6 0.0 7.9e-17 61.3 0.0 1.6 2 0 0 2 2 2 1 GTP cyclohydrolase II Ank_2 PF12796.7 ORX91189.1 - 1.2e-17 64.3 0.0 9.7e-08 32.5 0.0 4.0 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORX91189.1 - 3.2e-12 46.7 0.3 0.12 13.0 0.0 5.7 6 0 0 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORX91189.1 - 3.7e-11 42.2 2.4 0.057 14.0 0.0 6.5 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 ORX91189.1 - 1.1e-09 38.3 0.1 0.29 11.5 0.0 4.9 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 ORX91189.1 - 2e-07 31.2 0.1 1 9.9 0.0 5.0 4 0 0 4 4 4 2 Ankyrin repeat AbiEii PF08843.11 ORX91337.1 - 0.048 13.6 0.0 0.21 11.5 0.0 1.8 1 1 0 1 1 1 0 Nucleotidyl transferase AbiEii toxin, Type IV TA system DDE_1 PF03184.19 ORX91339.1 - 0.067 12.9 0.0 0.069 12.8 0.0 1.1 1 0 0 1 1 1 0 DDE superfamily endonuclease Fungal_trans PF04082.18 ORX91356.1 - 9.7e-43 146.1 0.1 2.1e-42 145.0 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain FAD_binding_3 PF01494.19 ORX91357.1 - 2.5e-78 263.8 1.2 6.7e-74 249.2 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain Phe_hydrox_dim PF07976.12 ORX91357.1 - 1.8e-27 96.4 0.0 3.9e-27 95.3 0.0 1.5 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox_2 PF07992.14 ORX91357.1 - 7.9e-05 22.0 0.0 0.32 10.2 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ORX91357.1 - 0.00093 18.9 2.6 0.19 11.3 0.0 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.17 ORX91357.1 - 0.0018 17.6 0.0 0.0097 15.2 0.0 2.0 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.27 ORX91357.1 - 0.0025 18.3 0.2 1.4 9.5 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ORX91357.1 - 0.02 13.6 0.1 0.045 12.5 0.1 1.5 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_2 PF00890.24 ORX91357.1 - 0.029 13.5 0.2 0.36 9.9 0.1 2.7 4 0 0 4 4 4 0 FAD binding domain Inj_translocase PF16928.5 ORX91357.1 - 0.093 12.2 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 DNA/protein translocase of phage P22 injectosome Lycopene_cycl PF05834.12 ORX91357.1 - 0.097 11.7 0.1 0.18 10.8 0.1 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Amidase PF01425.21 ORX91358.1 - 1.4e-83 281.4 0.0 1.8e-83 281.0 0.0 1.1 1 0 0 1 1 1 1 Amidase Polysacc_deac_1 PF01522.21 ORX91359.1 - 9.2e-20 70.8 0.0 1.7e-19 69.9 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 ORX91359.1 - 1.1e-05 25.2 0.1 3.9e-05 23.4 0.0 2.0 2 1 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2334) FAD_binding_3 PF01494.19 ORX91360.1 - 7.9e-12 45.1 0.0 1e-11 44.7 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 ORX91360.1 - 3.5e-07 30.1 6.6 0.0046 16.6 0.1 2.3 2 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ORX91360.1 - 7.1e-07 28.7 0.0 0.0012 18.2 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ORX91360.1 - 0.00014 21.1 0.3 0.0002 20.5 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 ORX91360.1 - 0.0011 17.8 0.0 0.081 11.6 0.1 2.0 2 0 0 2 2 2 1 HI0933-like protein Trp_halogenase PF04820.14 ORX91360.1 - 0.0019 17.2 4.7 0.12 11.2 0.1 2.1 1 1 1 2 2 2 2 Tryptophan halogenase NAD_binding_8 PF13450.6 ORX91360.1 - 0.0022 18.2 2.7 0.0047 17.1 1.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 ORX91360.1 - 0.0046 16.1 0.2 0.013 14.6 0.2 1.5 1 1 0 1 1 1 1 Lycopene cyclase protein FAD_oxidored PF12831.7 ORX91360.1 - 0.0049 16.3 0.2 0.0072 15.7 0.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 ORX91360.1 - 0.014 14.7 0.1 0.34 10.2 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 ORX91360.1 - 0.035 14.7 0.2 1.3 9.7 0.3 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 ORX91360.1 - 0.09 11.8 0.2 0.12 11.4 0.2 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 ORX91360.1 - 0.1 11.9 0.4 0.14 11.3 0.4 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ORX91360.1 - 0.2 11.7 2.0 14 5.7 0.5 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding RNase_PH PF01138.21 ORX91393.1 - 1.3e-11 45.1 0.1 2.1e-11 44.5 0.1 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 UQ_con PF00179.26 ORX91394.1 - 9.6e-40 135.5 0.0 1.1e-39 135.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UFC1 PF08694.11 ORX91394.1 - 0.028 14.0 0.0 0.036 13.7 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 Prok-E2_B PF14461.6 ORX91394.1 - 0.042 13.6 0.0 0.049 13.3 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B Gtr1_RagA PF04670.12 ORX91401.1 - 0.088 12.2 0.2 0.31 10.3 0.0 1.9 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region PEP-utilisers_N PF05524.13 ORX91401.1 - 5.6 7.2 8.9 5.1 7.3 1.7 2.8 1 1 0 2 2 2 0 PEP-utilising enzyme, N-terminal DUF1515 PF07439.11 ORX91401.1 - 8.3 6.5 12.6 15 5.6 3.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) Patatin PF01734.22 ORX91403.1 - 3.6e-20 73.0 0.0 5.6e-20 72.4 0.0 1.3 1 0 0 1 1 1 1 Patatin-like phospholipase AAA_12 PF13087.6 ORX91405.1 - 2.1e-23 83.0 0.3 2.3e-23 82.9 0.3 1.0 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 ORX91405.1 - 0.019 14.7 0.0 0.019 14.7 0.0 1.1 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.6 ORX91405.1 - 0.041 13.7 0.4 0.069 13.0 0.4 1.5 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain Ank_2 PF12796.7 ORX91468.1 - 3e-21 75.8 0.0 8e-11 42.4 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORX91468.1 - 1.6e-19 70.0 0.0 7.9e-09 35.9 0.0 3.1 3 0 0 3 3 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORX91468.1 - 6.8e-15 53.7 0.0 0.016 15.7 0.0 5.2 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 ORX91468.1 - 8.3e-15 54.7 0.0 5.3e-07 29.8 0.0 3.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 ORX91468.1 - 2.8e-13 49.7 0.0 0.016 15.7 0.0 5.0 4 0 0 4 4 4 3 Ankyrin repeat NACHT PF05729.12 ORX91468.1 - 3.4e-09 36.8 0.5 1.7e-08 34.5 0.5 2.3 1 1 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 ORX91468.1 - 2e-05 24.9 0.0 0.00012 22.4 0.0 2.3 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 ORX91468.1 - 0.00016 22.1 0.1 0.00099 19.5 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain Helo_like_N PF17111.5 ORX91468.1 - 0.00032 20.1 1.2 0.0016 17.9 0.0 2.7 3 1 0 3 3 3 1 Fungal N-terminal domain of STAND proteins SesA PF17107.5 ORX91468.1 - 0.0068 16.6 0.2 0.048 13.8 0.1 2.6 2 1 0 2 2 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases DUF4495 PF14906.6 ORX91468.1 - 0.013 14.6 0.1 0.027 13.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4495) GvpD PF07088.11 ORX91468.1 - 0.027 13.1 0.0 0.048 12.3 0.0 1.3 1 0 0 1 1 1 0 GvpD gas vesicle protein FliT PF05400.13 ORX91468.1 - 0.03 15.1 1.5 0.49 11.3 0.4 3.2 3 0 0 3 3 2 0 Flagellar protein FliT AAA_19 PF13245.6 ORX91468.1 - 0.066 13.5 0.2 0.62 10.4 0.0 2.6 2 1 1 3 3 3 0 AAA domain RhoGAP PF00620.27 ORX91468.1 - 0.11 12.3 0.1 0.37 10.6 0.1 1.8 1 0 0 1 1 1 0 RhoGAP domain AAA_30 PF13604.6 ORX91468.1 - 0.11 12.2 0.0 0.43 10.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain Bcr-Abl_Oligo PF09036.10 ORX91468.1 - 0.26 11.3 1.0 0.81 9.7 0.1 2.4 2 1 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain tRNA-synt_2b PF00587.25 ORX91470.1 - 1.8e-34 119.2 0.0 3.6e-34 118.3 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 ORX91470.1 - 1.2e-19 70.6 5.6 2.3e-19 69.6 5.6 1.5 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain TssO PF17561.2 ORX91470.1 - 0.14 12.2 3.4 0.28 11.3 3.4 1.5 1 0 0 1 1 1 0 Type VI secretion system, TssO DUF4208 PF13907.6 ORX91470.1 - 0.46 11.0 3.9 1 9.9 3.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4208) PsbQ PF05757.11 ORX91470.1 - 4.9 6.8 8.8 0.52 10.0 3.0 2.1 2 0 0 2 2 2 0 Oxygen evolving enhancer protein 3 (PsbQ) Ras PF00071.22 ORX91471.1 - 3.5e-45 153.5 0.2 4e-45 153.3 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORX91471.1 - 1.1e-15 57.9 0.1 1.5e-15 57.4 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORX91471.1 - 7.8e-08 32.0 0.0 8.4e-08 31.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 ORX91471.1 - 2.1e-05 24.0 0.0 2.6e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 ORX91471.1 - 0.0004 20.0 0.2 0.005 16.4 0.1 2.1 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 ORX91471.1 - 0.00086 19.4 0.0 0.0012 18.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ORX91471.1 - 0.0065 16.4 0.0 1.1 9.1 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase AAA_14 PF13173.6 ORX91471.1 - 0.028 14.5 0.0 0.046 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATP-synt_ab PF00006.25 ORX91471.1 - 0.054 13.1 0.1 0.47 10.1 0.1 2.0 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain WAPL PF07814.13 ORX91472.1 - 3.1e-16 59.1 0.1 6.9e-16 58.0 0.0 1.5 2 0 0 2 2 2 1 Wings apart-like protein regulation of heterochromatin DUF383 PF04063.14 ORX91472.1 - 0.0025 17.5 0.0 0.0034 17.1 0.0 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF383) Tho2 PF11262.8 ORX91512.1 - 0.05 12.8 3.3 0.063 12.5 3.3 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 PBP_GOBP PF01395.22 ORX91512.1 - 0.065 13.4 0.1 0.093 12.9 0.1 1.2 1 0 0 1 1 1 0 PBP/GOBP family MscS_TM PF12794.7 ORX91513.1 - 0.1 11.4 3.0 0.12 11.2 3.0 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 DUF3987 PF13148.6 ORX91513.1 - 0.3 10.1 6.6 0.34 9.9 6.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Pkinase PF00069.25 ORX91514.1 - 5.3e-15 55.5 0.0 9e-11 41.6 0.0 3.0 2 1 1 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORX91514.1 - 1.3e-12 47.5 0.0 2.5e-09 36.8 0.0 2.9 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 ORX91514.1 - 0.027 14.4 2.6 0.064 13.2 0.1 2.6 3 0 0 3 3 3 0 Phosphotransferase enzyme family DUF3723 PF12520.8 ORX91555.1 - 3e-13 49.3 0.0 3.7e-13 49.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3723) BCL9 PF11502.8 ORX91555.1 - 0.032 14.0 0.5 0.057 13.2 0.5 1.3 1 0 0 1 1 1 0 B-cell lymphoma 9 protein Spore_GerQ PF09671.10 ORX91557.1 - 0.034 14.1 0.0 0.044 13.8 0.0 1.1 1 0 0 1 1 1 0 Spore coat protein (Spore_GerQ) Cellulase PF00150.18 ORX91558.1 - 2.6e-44 151.8 6.0 4.2e-44 151.1 6.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_X2 PF03442.14 ORX91558.1 - 1e-16 60.8 1.8 1e-15 57.6 0.1 2.8 3 0 0 3 3 3 1 Carbohydrate binding domain X2 CBM46 PF18448.1 ORX91558.1 - 0.0088 16.3 1.3 0.075 13.3 0.3 3.0 3 0 0 3 3 3 1 Carbohydrate binding domain Gin PF10764.9 ORX91559.1 - 0.061 13.3 0.2 0.091 12.7 0.2 1.2 1 0 0 1 1 1 0 Inhibitor of sigma-G Gin zf-met2 PF12907.7 ORX91559.1 - 0.11 12.7 0.9 0.19 11.9 0.9 1.5 1 0 0 1 1 1 0 Zinc-binding YfhE PF14152.6 ORX91559.1 - 0.12 12.5 0.1 0.2 11.7 0.1 1.4 1 0 0 1 1 1 0 YfhE-like protein Enterotoxin_a PF01375.17 ORX91575.1 - 1.8e-07 31.1 0.0 4.8e-07 29.6 0.0 1.6 1 1 0 1 1 1 1 Heat-labile enterotoxin alpha chain Pertussis_S1 PF02917.14 ORX91575.1 - 0.037 13.8 0.0 0.048 13.4 0.0 1.2 1 0 0 1 1 1 0 Pertussis toxin, subunit 1 Ldh_1_N PF00056.23 ORX91585.1 - 1.7e-32 112.5 0.0 2.5e-32 111.9 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 ORX91585.1 - 8.5e-20 71.3 0.0 1.4e-19 70.6 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain F420_oxidored PF03807.17 ORX91585.1 - 0.0011 19.5 0.0 0.0078 16.8 0.1 2.4 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 ORX91585.1 - 0.0044 16.7 0.1 0.0087 15.7 0.1 1.6 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.18 ORX91585.1 - 0.012 15.8 0.1 0.026 14.8 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain DAO PF01266.24 ORX91585.1 - 0.05 13.2 0.4 3.4 7.1 0.1 2.3 1 1 1 2 2 2 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 ORX91585.1 - 0.09 13.2 0.0 0.2 12.1 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding HBS1_N PF08938.10 ORX91585.1 - 0.09 13.1 0.2 0.16 12.3 0.2 1.3 1 0 0 1 1 1 0 HBS1 N-terminus NAD_Gly3P_dh_N PF01210.23 ORX91585.1 - 0.12 12.3 0.1 7.4 6.5 0.0 2.6 3 0 0 3 3 3 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Peptidase_M19 PF01244.21 ORX91587.1 - 2.2e-101 339.2 0.0 2.6e-101 339.0 0.0 1.1 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Ilm1 PF10311.9 ORX91588.1 - 8.3e-59 197.9 1.1 9.4e-59 197.7 1.1 1.0 1 0 0 1 1 1 1 Increased loss of mitochondrial DNA protein 1 DUF4345 PF14248.6 ORX91588.1 - 0.15 12.0 4.0 1.5 8.7 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4345) DUF202 PF02656.15 ORX91589.1 - 1.7e-17 63.6 0.0 2.6e-16 59.8 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) FAD_binding_3 PF01494.19 ORX91590.1 - 1.5e-10 40.9 0.0 6.1e-10 38.9 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 ORX91590.1 - 7e-07 29.1 0.3 2e-05 24.4 0.0 2.6 2 1 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ORX91590.1 - 5.8e-05 22.5 0.1 0.14 11.4 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORX91590.1 - 0.0044 17.2 0.0 0.012 15.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 ORX91590.1 - 0.096 11.7 0.1 0.18 10.8 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 ORX91590.1 - 0.17 12.5 0.1 21 5.8 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 ORX91590.1 - 0.24 10.2 1.3 0.51 9.1 0.0 2.1 3 0 0 3 3 3 0 Tryptophan halogenase PALP PF00291.25 ORX91591.1 - 1.3e-33 116.7 0.2 1.5e-33 116.5 0.2 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PPTA PF01239.22 ORX91592.1 - 1.6e-42 142.0 15.8 2e-09 36.9 0.4 6.3 6 0 0 6 6 6 6 Protein prenyltransferase alpha subunit repeat TPR_17 PF13431.6 ORX91592.1 - 0.0022 18.2 0.6 5.1 7.7 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 ORX91592.1 - 0.0058 17.4 1.5 77 4.5 0.0 4.4 3 1 1 4 4 4 0 Tetratricopeptide repeat adh_short PF00106.25 ORX91593.1 - 2.2e-43 148.0 1.0 2.8e-43 147.7 1.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORX91593.1 - 3.5e-32 111.8 1.0 4.4e-32 111.5 1.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORX91593.1 - 2.6e-11 43.8 0.2 4e-11 43.1 0.2 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 ORX91593.1 - 0.00032 19.9 0.0 0.00036 19.8 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 ORX91593.1 - 0.0013 18.3 0.2 0.023 14.1 0.2 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 ORX91593.1 - 0.0033 16.8 0.0 0.0046 16.4 0.0 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) MFS_1 PF07690.16 ORX91594.1 - 0.00033 19.7 0.1 0.00035 19.6 0.1 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily adh_short PF00106.25 ORX91624.1 - 1.3e-34 119.4 0.0 1.8e-34 118.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORX91624.1 - 8.7e-29 100.7 0.0 1.1e-28 100.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 ORX91624.1 - 2.1e-05 24.1 0.0 0.16 11.4 0.0 2.4 2 1 0 2 2 2 2 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.6 ORX91624.1 - 7.3e-05 22.7 0.0 0.00019 21.4 0.0 1.6 2 0 0 2 2 2 1 NAD(P)H-binding F420_oxidored PF03807.17 ORX91624.1 - 0.11 13.0 0.0 0.28 11.8 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DUF2053 PF09767.9 ORX91624.1 - 0.14 12.3 0.1 1.8 8.7 0.0 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2053) IlvN PF07991.12 ORX91624.1 - 0.17 11.5 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Methyltransf_2 PF00891.18 ORX91625.1 - 6.5e-19 68.1 0.0 9.7e-19 67.5 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_25 PF13649.6 ORX91625.1 - 5.6e-06 27.0 0.0 1.7e-05 25.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORX91625.1 - 6.5e-05 23.6 0.0 0.00018 22.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 ORX91625.1 - 0.0029 17.2 0.0 0.0049 16.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 ORX91625.1 - 0.016 15.8 0.0 0.043 14.5 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 ORX91625.1 - 0.06 13.2 0.0 0.098 12.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Zn_clus PF00172.18 ORX91626.1 - 5.5e-08 32.8 11.1 1.2e-07 31.7 11.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain YHYH PF14240.6 ORX91626.1 - 0.021 14.8 0.5 0.73 9.8 0.0 2.2 2 0 0 2 2 2 0 YHYH protein Acyl-CoA_dh_1 PF00441.24 ORX91627.1 - 0.072 13.3 0.0 0.082 13.1 0.0 1.1 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.6 ORX91628.1 - 6.8e-08 33.1 0.0 1e-07 32.5 0.0 1.3 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 ORX91628.1 - 0.047 13.9 0.1 0.17 12.1 0.1 1.9 1 1 0 1 1 1 0 Acyl-CoA dehydrogenase, middle domain F-box-like PF12937.7 ORX91629.1 - 0.002 18.0 0.0 0.0033 17.3 0.0 1.4 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 ORX91629.1 - 0.0098 15.8 0.0 0.013 15.4 0.0 1.2 1 1 0 1 1 1 1 F-box F-box PF00646.33 ORX91629.1 - 0.045 13.7 0.0 0.095 12.6 0.0 1.6 1 0 0 1 1 1 0 F-box domain Peptidase_S8 PF00082.22 ORX91632.1 - 9.5e-19 67.8 0.0 1.5e-18 67.1 0.0 1.2 1 0 0 1 1 1 1 Subtilase family Fungal_lectin_2 PF18647.1 ORX91632.1 - 9e-09 35.7 0.1 1.8e-08 34.8 0.1 1.5 1 0 0 1 1 1 1 Alpha-galactosyl-binding fungal lectin ABC_tran PF00005.27 ORX91633.1 - 5e-43 146.9 0.0 1.8e-20 73.8 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 ORX91633.1 - 7.6e-22 78.2 10.1 7.6e-22 78.2 10.1 2.6 3 0 0 3 3 2 1 ABC transporter transmembrane region AAA_21 PF13304.6 ORX91633.1 - 1.4e-10 41.5 1.5 0.27 11.0 0.0 4.3 3 1 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ORX91633.1 - 2.1e-10 40.4 0.1 0.01 15.3 0.0 4.2 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 ORX91633.1 - 1.2e-07 31.3 0.1 0.009 15.7 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 ORX91633.1 - 1e-06 29.1 0.2 0.013 15.7 0.0 2.8 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.6 ORX91633.1 - 1.6e-06 28.6 0.2 0.037 14.4 0.0 2.9 2 0 0 2 2 2 2 AAA ATPase domain T2SSE PF00437.20 ORX91633.1 - 3.7e-06 26.2 0.0 0.0043 16.1 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein MMR_HSR1 PF01926.23 ORX91633.1 - 1.1e-05 25.5 0.0 0.14 12.3 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.6 ORX91633.1 - 1.4e-05 25.7 0.0 0.054 14.0 0.0 2.2 2 0 0 2 2 2 2 AAA domain DUF87 PF01935.17 ORX91633.1 - 3.4e-05 24.0 0.4 0.0049 17.0 0.1 2.2 2 0 0 2 2 2 1 Helicase HerA, central domain RsgA_GTPase PF03193.16 ORX91633.1 - 5.8e-05 23.0 0.0 0.36 10.7 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA PF00004.29 ORX91633.1 - 0.0001 22.7 0.0 0.19 12.2 0.0 3.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 ORX91633.1 - 0.00022 20.8 0.0 0.31 10.5 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_18 PF13238.6 ORX91633.1 - 0.00045 20.8 0.0 0.11 13.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 ORX91633.1 - 0.00051 20.2 0.0 0.058 13.6 0.0 2.8 3 0 0 3 3 2 1 AAA domain Adeno_IVa2 PF02456.15 ORX91633.1 - 0.00064 18.6 0.1 0.44 9.3 0.0 2.6 3 0 0 3 3 3 2 Adenovirus IVa2 protein Dynamin_N PF00350.23 ORX91633.1 - 0.002 18.2 0.1 1.1 9.3 0.0 2.3 2 0 0 2 2 2 1 Dynamin family Mg_chelatase PF01078.21 ORX91633.1 - 0.0022 17.4 0.0 2.6 7.4 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI FtsK_SpoIIIE PF01580.18 ORX91633.1 - 0.0036 16.7 0.1 2.3 7.5 0.1 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family cobW PF02492.19 ORX91633.1 - 0.0039 16.8 0.1 0.73 9.4 0.1 3.4 4 0 0 4 4 3 1 CobW/HypB/UreG, nucleotide-binding domain Zeta_toxin PF06414.12 ORX91633.1 - 0.0047 16.2 0.0 0.93 8.7 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin ATP_bind_1 PF03029.17 ORX91633.1 - 0.0086 15.9 0.1 0.19 11.5 0.1 2.4 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_25 PF13481.6 ORX91633.1 - 0.011 15.3 0.1 1.8 8.1 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_27 PF13514.6 ORX91633.1 - 0.014 15.0 0.0 0.046 13.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 ORX91633.1 - 0.015 15.1 0.0 2.2 7.9 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain DUF815 PF05673.13 ORX91633.1 - 0.021 14.0 0.0 2.4 7.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) SbcCD_C PF13558.6 ORX91633.1 - 0.022 15.0 8.8 1.6 9.1 0.6 4.3 3 1 0 3 3 3 0 Putative exonuclease SbcCD, C subunit RNA_helicase PF00910.22 ORX91633.1 - 0.032 14.6 0.0 8.3 6.9 0.0 2.5 2 0 0 2 2 2 0 RNA helicase IstB_IS21 PF01695.17 ORX91633.1 - 0.043 13.5 3.1 15 5.3 0.0 4.1 5 0 0 5 5 5 0 IstB-like ATP binding protein AAA_5 PF07728.14 ORX91633.1 - 0.051 13.6 0.5 14 5.7 0.0 3.1 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 ORX91633.1 - 0.065 12.9 0.1 5.7 6.6 0.0 2.6 3 0 0 3 3 2 0 AAA domain CLP1_P PF16575.5 ORX91633.1 - 0.077 12.8 0.3 0.76 9.5 0.0 2.2 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop TsaE PF02367.17 ORX91633.1 - 0.13 12.3 0.0 1.8 8.5 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE GTP_EFTU PF00009.27 ORX91633.1 - 0.15 11.6 0.0 14 5.1 0.0 2.8 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 ORX91633.1 - 0.18 11.5 0.2 1.8 8.3 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.12 ORX91633.1 - 0.26 11.2 1.2 23 4.8 0.0 2.9 3 0 0 3 3 2 0 NACHT domain AMP-binding PF00501.28 ORX91634.1 - 5.2e-62 209.8 0.1 9.2e-58 195.8 0.0 2.9 2 1 0 2 2 2 1 AMP-binding enzyme Condensation PF00668.20 ORX91634.1 - 3.1e-14 52.5 0.0 5.1e-14 51.8 0.0 1.2 1 0 0 1 1 1 1 Condensation domain PP-binding PF00550.25 ORX91634.1 - 0.00046 20.5 0.1 0.0012 19.1 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.6 ORX91634.1 - 0.0091 16.9 0.0 0.024 15.6 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain 2OG-FeII_Oxy PF03171.20 ORX91635.1 - 1.1e-12 48.3 0.0 3.6e-12 46.7 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 ORX91635.1 - 3.6e-09 37.4 0.0 6.1e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal TAT_signal PF10518.9 ORX91635.1 - 0.064 13.1 0.1 0.13 12.1 0.1 1.6 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence MRP-S28 PF10213.9 ORX91670.1 - 3e-41 140.8 0.0 6.4e-41 139.7 0.0 1.6 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein KCT2 PF17818.1 ORX91670.1 - 0.013 15.7 0.1 0.021 14.9 0.1 1.3 1 0 0 1 1 1 0 Keratinocyte-associated gene product Glyco_tran_28_C PF04101.16 ORX91671.1 - 1.1e-19 71.1 0.1 1.3e-19 70.7 0.1 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain UDPGT PF00201.18 ORX91671.1 - 0.12 11.1 0.0 0.19 10.5 0.0 1.3 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase Cupin_1 PF00190.22 ORX91672.1 - 5.1e-39 133.3 0.8 5.7e-19 68.2 0.2 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 ORX91672.1 - 1.7e-22 78.9 0.1 1e-12 47.6 0.0 2.5 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 ORX91672.1 - 4e-09 36.0 0.0 0.00043 19.9 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF861) MannoseP_isomer PF01050.18 ORX91672.1 - 4.2e-07 30.0 0.0 7.1e-06 26.0 0.0 2.1 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase 3-HAO PF06052.12 ORX91672.1 - 0.00011 21.9 0.0 0.00073 19.2 0.0 2.0 2 0 0 2 2 2 1 3-hydroxyanthranilic acid dioxygenase AraC_binding PF02311.19 ORX91672.1 - 0.00013 21.9 0.1 0.011 15.6 0.0 2.5 3 0 0 3 3 3 1 AraC-like ligand binding domain Cupin_6 PF12852.7 ORX91672.1 - 0.0031 17.3 0.0 2.3 7.9 0.0 2.4 2 0 0 2 2 2 2 Cupin Cupin_7 PF12973.7 ORX91672.1 - 0.05 13.5 0.0 4.3 7.3 0.0 2.4 2 0 0 2 2 2 0 ChrR Cupin-like domain MFS_1 PF07690.16 ORX91673.1 - 0.00048 19.1 19.7 0.00048 19.1 19.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF5353 PF17304.2 ORX91673.1 - 1.3 8.8 9.7 5.6 6.8 0.1 3.1 2 2 0 2 2 2 0 Family of unknown function (DUF5353) AMP-binding PF00501.28 ORX91674.1 - 2e-94 316.6 0.0 2.5e-94 316.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORX91674.1 - 7.8e-13 49.2 0.2 2e-12 47.9 0.2 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Acetyltransf_8 PF13523.6 ORX91675.1 - 2.8e-45 153.6 1.8 4e-45 153.1 1.8 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain K_oxygenase PF13434.6 ORX91676.1 - 2.3e-53 181.5 0.0 6.8e-53 180.0 0.0 1.6 1 1 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 ORX91676.1 - 0.071 12.4 0.0 0.46 9.7 0.0 2.0 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ABC_membrane PF00664.23 ORX91677.1 - 9.6e-50 169.8 5.5 1.2e-49 169.4 5.5 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region DUF2207 PF09972.9 ORX91677.1 - 0.3 9.8 9.1 1.3 7.7 2.1 2.8 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) SfLAP PF11139.8 ORX91677.1 - 1.6 8.1 8.1 2.7 7.4 0.6 3.3 4 0 0 4 4 4 0 Sap, sulfolipid-1-addressing protein ABC_tran PF00005.27 ORX91678.1 - 2.4e-16 60.5 0.0 3.6e-16 59.9 0.0 1.3 1 0 0 1 1 1 1 ABC transporter APS_kinase PF01583.20 ORX91678.1 - 0.00011 22.2 0.1 0.00015 21.7 0.1 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase Zeta_toxin PF06414.12 ORX91678.1 - 0.00034 19.9 0.0 0.00048 19.5 0.0 1.1 1 0 0 1 1 1 1 Zeta toxin AAA_29 PF13555.6 ORX91678.1 - 0.00092 18.9 0.1 0.0016 18.1 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 ORX91678.1 - 0.0058 17.2 0.0 0.0074 16.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 ORX91678.1 - 0.0064 16.4 0.0 0.0069 16.3 0.0 1.1 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 ORX91678.1 - 0.007 16.8 0.0 0.0088 16.4 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain DUF87 PF01935.17 ORX91678.1 - 0.008 16.3 0.1 0.011 15.8 0.1 1.2 1 0 0 1 1 1 1 Helicase HerA, central domain AAA_22 PF13401.6 ORX91678.1 - 0.0093 16.2 0.0 0.012 15.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 ORX91678.1 - 0.012 15.1 0.0 0.016 14.8 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 ORX91678.1 - 0.014 15.6 0.0 0.016 15.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.6 ORX91678.1 - 0.02 14.7 0.1 0.025 14.4 0.1 1.1 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system NB-ARC PF00931.22 ORX91678.1 - 0.037 13.2 0.0 0.044 13.0 0.0 1.1 1 0 0 1 1 1 0 NB-ARC domain AAA_30 PF13604.6 ORX91678.1 - 0.039 13.7 0.0 0.046 13.4 0.0 1.1 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 ORX91678.1 - 0.06 13.4 0.0 0.1 12.7 0.0 1.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_15 PF13175.6 ORX91678.1 - 0.074 12.8 0.0 0.083 12.6 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 ORX91678.1 - 0.089 13.3 0.0 0.12 12.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF3987 PF13148.6 ORX91678.1 - 0.12 11.4 0.0 0.13 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) SRP54 PF00448.22 ORX91678.1 - 0.12 12.0 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ABC_tran PF00005.27 ORX91739.1 - 1.9e-29 102.9 0.2 7e-15 55.8 0.3 2.7 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 ORX91739.1 - 1.1e-07 32.0 0.0 0.18 11.6 0.0 3.4 3 0 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ORX91739.1 - 0.0018 17.7 0.1 5.1 6.5 0.0 3.1 2 1 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 ORX91739.1 - 0.0096 15.7 0.3 0.023 14.4 0.3 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_27 PF13514.6 ORX91739.1 - 0.011 15.4 0.0 0.019 14.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain EB PF01683.18 ORX91740.1 - 1.1 9.5 23.8 1.9 8.8 10.4 2.2 1 1 1 2 2 2 0 EB module TMEM71 PF15121.6 ORX91749.1 - 0.02 14.6 0.0 0.053 13.2 0.0 1.6 1 0 0 1 1 1 0 TMEM71 protein family Hemerythrin PF01814.23 ORX91751.1 - 0.00025 21.7 0.0 0.00038 21.1 0.0 1.3 1 1 0 1 1 1 1 Hemerythrin HHE cation binding domain ADH_zinc_N PF00107.26 ORX91752.1 - 1.2e-19 70.6 0.0 2.1e-19 69.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ORX91752.1 - 1e-14 55.7 0.0 1.6e-14 55.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ORX91752.1 - 1.6e-07 31.2 0.0 3.7e-07 30.0 0.0 1.6 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 ORX91752.1 - 0.002 17.6 0.0 0.0031 17.0 0.0 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus RLL PF10036.9 ORX91752.1 - 0.09 12.6 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 RNA transcription, translation and transport factor protein WD40 PF00400.32 ORX91769.1 - 7.6e-44 146.8 9.2 2.7e-10 40.6 0.0 5.5 4 1 1 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX91769.1 - 6e-19 68.1 0.0 0.00023 21.4 0.0 4.4 1 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Proteasome_A_N PF10584.9 ORX91769.1 - 9e-13 47.6 0.0 0.26 11.0 0.0 5.3 5 0 0 5 5 5 5 Proteasome subunit A N-terminal signature Ge1_WD40 PF16529.5 ORX91769.1 - 2.4e-11 43.2 0.8 0.024 13.6 0.0 4.1 1 1 4 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 ORX91769.1 - 7.4e-10 38.5 2.4 4.2 7.4 0.0 5.3 5 0 0 5 5 5 4 WD40-like Beta Propeller Repeat Ret2_MD PF18528.1 ORX91769.1 - 5.6e-06 26.7 0.0 5.3 7.5 0.0 4.9 1 1 4 5 5 5 1 RNA editing 3' terminal uridylyl transferase 2 middle domain TruB_C PF09142.11 ORX91769.1 - 0.00035 20.3 1.5 8.4 6.3 0.0 4.6 5 0 0 5 5 5 0 tRNA Pseudouridine synthase II, C terminal SRF-TF PF00319.18 ORX91769.1 - 0.00068 19.1 0.0 55 3.4 0.0 4.9 5 0 0 5 5 5 0 SRF-type transcription factor (DNA-binding and dimerisation domain) IKI3 PF04762.12 ORX91769.1 - 0.00086 17.4 0.3 0.065 11.2 0.2 2.5 1 1 1 2 2 2 2 IKI3 family Nup160 PF11715.8 ORX91769.1 - 0.0028 16.4 0.1 1.7 7.2 0.0 2.9 1 1 2 3 3 3 1 Nucleoporin Nup120/160 Glyoxal_oxid_N PF07250.11 ORX91769.1 - 0.0029 16.8 0.2 8 5.6 0.0 3.8 1 1 3 4 4 4 1 Glyoxal oxidase N-terminus Cytochrom_D1 PF02239.16 ORX91769.1 - 0.0098 14.5 0.1 0.11 11.0 0.1 2.1 1 1 1 2 2 2 1 Cytochrome D1 heme domain eIF2A PF08662.11 ORX91769.1 - 0.011 15.7 0.0 6.3 6.6 0.0 2.7 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A GluRS_N PF18466.1 ORX91769.1 - 0.013 15.9 0.3 55 4.3 0.0 3.3 3 0 0 3 3 3 0 Glutamate--tRNA ligase N-terminal domain Nbas_N PF15492.6 ORX91769.1 - 0.039 13.3 0.7 12 5.1 0.0 3.2 1 1 3 4 4 4 0 Neuroblastoma-amplified sequence, N terminal Nucleoporin_N PF08801.11 ORX91769.1 - 0.041 12.6 0.0 5.9 5.5 0.0 2.5 1 1 2 3 3 3 0 Nup133 N terminal like Tox-GHH PF15636.6 ORX91769.1 - 0.047 13.7 6.3 20 5.2 0.2 3.2 3 0 0 3 3 3 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin VAD1-2 PF15310.6 ORX91769.1 - 0.084 12.7 0.0 1.1e+02 2.5 0.0 3.6 1 1 1 4 4 4 0 Vitamin A-deficiency (VAD) rat model signalling WD40_like PF17005.5 ORX91769.1 - 0.11 11.8 0.0 12 5.2 0.0 2.7 2 1 2 4 4 4 0 WD40-like domain TIP_N PF12457.8 ORX91769.1 - 0.11 12.8 0.0 59 4.1 0.0 3.1 1 1 2 3 3 3 0 Tuftelin interacting protein N terminal Peptidase_S9_N PF02897.15 ORX91769.1 - 0.13 11.1 1.0 29 3.3 0.0 3.4 2 1 1 4 4 4 0 Prolyl oligopeptidase, N-terminal beta-propeller domain DUF2527 PF10736.9 ORX91769.1 - 0.25 11.2 1.9 76 3.3 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2627) LINES_C PF14695.6 ORX91770.1 - 0.15 11.5 0.0 0.29 10.6 0.0 1.4 1 0 0 1 1 1 0 Lines C-terminus RcpC PF16976.5 ORX91771.1 - 0.0092 16.0 1.1 0.016 15.2 1.1 1.5 1 0 0 1 1 1 1 Flp pilus assembly protein RcpC/CpaB Fungal_trans_2 PF11951.8 ORX91772.1 - 4.7e-11 42.1 0.0 6.7e-11 41.6 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain NMDAR2_C PF10565.9 ORX91772.1 - 0.79 8.5 6.9 1 8.1 6.9 1.0 1 0 0 1 1 1 0 N-methyl D-aspartate receptor 2B3 C-terminus HET PF06985.11 ORX91802.1 - 1.3e-11 45.0 0.3 1.5e-11 44.9 0.3 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Abhydrolase_6 PF12697.7 ORX91831.1 - 0.0033 18.1 0.0 0.0038 17.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 ORX91831.1 - 0.026 14.3 0.0 0.027 14.2 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Hydrolase_4 PF12146.8 ORX91831.1 - 0.11 11.8 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 GST_N_4 PF17172.4 ORX91862.1 - 2.9e-18 66.4 0.0 3.9e-18 66.0 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 ORX91862.1 - 0.00017 21.3 0.1 0.0017 18.1 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 ORX91862.1 - 0.035 14.4 0.0 0.047 14.0 0.0 1.2 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein PTPRCAP PF15713.5 ORX91863.1 - 0.14 12.5 8.4 0.29 11.4 8.4 1.5 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Nop14 PF04147.12 ORX91863.1 - 0.26 9.4 10.4 0.44 8.7 10.4 1.3 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 ORX91863.1 - 0.72 9.2 10.2 1.1 8.6 10.2 1.2 1 0 0 1 1 1 0 SDA1 Pes-10 PF07149.11 ORX91863.1 - 2.7 6.9 9.7 3.9 6.4 9.7 1.2 1 0 0 1 1 1 0 Pes-10 AA_permease_2 PF13520.6 ORX91864.1 - 7.1e-53 180.0 42.5 8.5e-53 179.7 42.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ORX91864.1 - 1.6e-28 99.6 30.9 1.6e-28 99.6 30.9 1.4 2 0 0 2 2 2 1 Amino acid permease DUF3328 PF11807.8 ORX91866.1 - 5.1e-26 91.8 1.3 7.4e-26 91.3 1.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Acetyltransf_1 PF00583.25 ORX91867.1 - 1.1e-08 35.3 0.0 1.6e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ORX91867.1 - 4.3e-06 27.1 0.0 1.1e-05 25.7 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ORX91867.1 - 0.00096 19.1 0.0 0.0018 18.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain NMO PF03060.15 ORX91869.1 - 1.1e-56 192.7 1.7 1.5e-56 192.2 1.7 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 ORX91869.1 - 1e-11 44.4 1.6 1.9e-11 43.6 1.6 1.4 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 ORX91869.1 - 1.2e-06 27.8 1.2 2.4e-06 26.8 1.2 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 ORX91869.1 - 8.3e-05 21.9 1.7 0.00013 21.2 1.0 1.6 2 0 0 2 2 2 1 Conserved region in glutamate synthase DHO_dh PF01180.21 ORX91869.1 - 0.0037 16.5 0.1 0.0057 15.9 0.1 1.3 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase HPPK PF01288.20 ORX91870.1 - 1.6e-25 89.8 0.1 3.7e-23 82.2 0.1 2.3 1 1 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) Trs65 PF12735.7 ORX91974.1 - 4.9e-78 262.7 0.0 6.4e-78 262.3 0.0 1.2 1 0 0 1 1 1 1 TRAPP trafficking subunit Trs65 Mpv17_PMP22 PF04117.12 ORX91974.1 - 1e-19 70.5 0.5 2.7e-19 69.2 0.3 1.9 2 0 0 2 2 2 1 Mpv17 / PMP22 family PGK PF00162.19 ORX91975.1 - 1.2e-151 505.0 2.0 1.3e-151 504.8 2.0 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase SBP_bac_8 PF13416.6 ORX91975.1 - 0.023 14.5 0.8 0.036 13.9 0.8 1.3 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein DUF3530 PF12048.8 ORX91975.1 - 0.045 13.2 0.0 0.069 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) DSS1_SEM1 PF05160.13 ORX91976.1 - 7.3e-23 80.4 14.7 8.9e-23 80.1 14.7 1.1 1 0 0 1 1 1 1 DSS1/SEM1 family DUF3808 PF10300.9 ORX91979.1 - 2.6e-139 465.1 0.0 3.4e-139 464.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) Ras PF00071.22 ORX91993.1 - 2.8e-44 150.6 0.0 3.1e-44 150.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORX91993.1 - 4.8e-21 75.2 0.0 5.6e-21 75.0 0.0 1.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORX91993.1 - 2.3e-05 23.9 0.0 2.8e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family DAP3 PF10236.9 ORX91993.1 - 0.24 10.5 0.0 0.28 10.3 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 CMS1 PF14617.6 ORX91995.1 - 1.3e-69 234.3 5.1 1.4e-69 234.2 5.1 1.0 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.29 ORX91995.1 - 0.00042 20.1 0.2 0.00061 19.6 0.2 1.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase CENP-T_C PF15511.6 ORX91996.1 - 1.8e-30 105.2 0.0 4.6e-30 103.9 0.0 1.6 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 ORX91996.1 - 5.4e-07 29.9 0.0 1.2e-06 28.8 0.0 1.5 1 0 0 1 1 1 1 CENP-S protein Histone PF00125.24 ORX91996.1 - 0.0011 19.3 0.0 0.0039 17.5 0.0 1.9 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.13 ORX91996.1 - 0.1 12.7 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Bromodomain associated PAXIP1_C PF15364.6 ORX91996.1 - 0.77 10.1 6.1 3 8.2 6.1 2.0 1 0 0 1 1 1 0 PAXIP1-associated-protein-1 C term PTIP binding protein SURF1 PF02104.15 ORX91997.1 - 2.7e-25 89.6 0.0 1e-24 87.8 0.0 1.8 1 1 0 1 1 1 1 SURF1 family DUF4512 PF14975.6 ORX91998.1 - 0.44 11.4 2.0 0.7 10.7 2.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4512) 2H-phosphodiest PF08975.10 ORX92000.1 - 9.2e-33 112.7 0.0 1.5e-32 112.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1868) CTK3 PF12243.8 ORX92051.1 - 6.5e-44 148.9 0.0 9.1e-44 148.4 0.0 1.2 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.8 ORX92051.1 - 5.8e-18 64.8 11.5 9.6e-18 64.1 11.5 1.4 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 C-terminus Ribosomal_L12 PF00542.19 ORX92052.1 - 1.4e-20 73.4 6.7 5.3e-20 71.5 5.5 2.0 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 ORX92052.1 - 9.6e-12 44.4 17.6 1.3e-10 40.8 13.0 3.5 3 1 0 3 3 3 1 Ribosomal protein L7/L12 dimerisation domain DUF2890 PF11081.8 ORX92052.1 - 0.086 12.9 0.5 0.11 12.5 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Ribosomal_60s PF00428.19 ORX92052.1 - 9.3 6.9 16.2 0.57 10.8 9.1 2.3 1 1 0 2 2 2 0 60s Acidic ribosomal protein AAA_5 PF07728.14 ORX92053.1 - 5.1e-128 421.7 0.2 4.3e-23 81.9 0.0 9.7 9 0 0 9 9 9 9 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 ORX92053.1 - 4.6e-55 184.3 7.8 1.5e-22 79.8 0.1 5.6 5 0 0 5 5 5 4 Midasin AAA lid domain AAA_3 PF07726.11 ORX92053.1 - 8.2e-31 106.6 0.0 9.3e-10 38.5 0.0 8.4 8 0 0 8 8 8 3 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 ORX92053.1 - 1.1e-28 100.0 0.1 3.1e-05 23.6 0.0 7.1 7 0 0 7 7 7 6 P-loop containing dynein motor region AAA PF00004.29 ORX92053.1 - 1.5e-28 99.8 0.0 0.00037 20.9 0.0 7.0 6 0 0 6 6 6 5 ATPase family associated with various cellular activities (AAA) AAA_lid_5 PF17865.1 ORX92053.1 - 1e-26 93.1 0.1 8.5e-26 90.1 0.0 2.6 2 0 0 2 2 2 1 Midasin AAA lid domain AAA_16 PF13191.6 ORX92053.1 - 1.7e-26 93.6 23.5 2.1e-05 25.0 0.7 9.9 9 2 0 9 9 7 6 AAA ATPase domain Dynein_heavy PF03028.15 ORX92053.1 - 9.9e-23 80.5 0.0 0.0014 18.7 0.0 7.4 8 0 0 8 8 6 4 Dynein heavy chain region D6 P-loop domain Sigma54_activat PF00158.26 ORX92053.1 - 1.5e-22 80.1 0.0 0.00036 20.3 0.0 6.2 6 0 0 6 6 5 5 Sigma-54 interaction domain AAA_6 PF12774.7 ORX92053.1 - 2e-22 79.6 0.0 0.00055 19.0 0.0 8.0 8 0 0 8 8 8 5 Hydrolytic ATP binding site of dynein motor region AAA_22 PF13401.6 ORX92053.1 - 3.6e-20 72.6 4.3 0.0003 21.1 0.0 7.6 7 0 0 7 7 6 4 AAA domain Sigma54_activ_2 PF14532.6 ORX92053.1 - 2.1e-19 70.0 1.6 0.00014 22.0 0.0 7.3 7 0 0 7 7 7 3 Sigma-54 interaction domain TsaE PF02367.17 ORX92053.1 - 4.4e-18 65.5 1.9 0.051 13.6 0.0 7.0 7 0 0 7 7 6 4 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 ORX92053.1 - 1.4e-16 60.7 0.0 0.00029 20.9 0.0 7.3 7 0 0 7 7 6 1 AAA domain AAA_18 PF13238.6 ORX92053.1 - 1.6e-16 61.0 6.3 0.25 11.9 0.0 7.9 7 0 0 7 7 6 4 AAA domain AAA_33 PF13671.6 ORX92053.1 - 4.5e-16 59.3 0.0 0.9 9.7 0.0 7.1 6 0 0 6 6 6 4 AAA domain AAA_30 PF13604.6 ORX92053.1 - 4.2e-15 56.0 0.0 0.19 11.4 0.0 7.9 7 1 0 7 7 7 2 AAA domain T2SSE PF00437.20 ORX92053.1 - 9e-15 54.5 3.6 0.0074 15.4 0.0 6.4 6 0 0 6 6 6 4 Type II/IV secretion system protein Mg_chelatase PF01078.21 ORX92053.1 - 6e-14 51.9 0.3 1.5 8.1 0.0 9.4 9 1 1 10 10 9 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 ORX92053.1 - 6.6e-14 52.2 0.8 0.05 14.0 0.0 6.6 6 0 0 6 6 6 3 RNA helicase NACHT PF05729.12 ORX92053.1 - 7.6e-14 52.0 3.0 0.078 12.9 0.0 6.6 6 0 0 6 6 6 3 NACHT domain RuvB_N PF05496.12 ORX92053.1 - 8.7e-14 51.6 2.0 0.014 15.1 0.0 6.7 7 0 0 7 7 6 2 Holliday junction DNA helicase RuvB P-loop domain AAA_19 PF13245.6 ORX92053.1 - 3.5e-12 46.9 3.9 0.84 10.0 0.0 7.3 6 0 0 6 6 6 2 AAA domain ABC_tran PF00005.27 ORX92053.1 - 6.5e-12 46.1 12.0 0.0056 17.2 0.0 8.2 9 1 1 10 10 6 2 ABC transporter IstB_IS21 PF01695.17 ORX92053.1 - 6.6e-11 42.3 0.1 0.086 12.6 0.0 6.1 6 0 0 6 6 6 2 IstB-like ATP binding protein AAA_25 PF13481.6 ORX92053.1 - 9.5e-11 41.6 1.8 0.47 10.0 0.0 6.1 6 0 0 6 6 5 2 AAA domain AAA_29 PF13555.6 ORX92053.1 - 1.6e-09 37.4 0.3 2.4 8.0 0.0 6.7 6 0 0 6 6 6 1 P-loop containing region of AAA domain Zeta_toxin PF06414.12 ORX92053.1 - 4.2e-09 36.0 3.1 0.86 8.8 0.0 6.9 7 0 0 7 7 7 1 Zeta toxin ATPase_2 PF01637.18 ORX92053.1 - 4.8e-09 36.5 0.0 2.2 8.2 0.0 6.3 6 0 0 6 6 6 1 ATPase domain predominantly from Archaea ResIII PF04851.15 ORX92053.1 - 1.7e-08 34.7 1.5 0.49 10.4 0.0 6.1 6 0 0 6 6 6 2 Type III restriction enzyme, res subunit Rad17 PF03215.15 ORX92053.1 - 2.7e-08 33.9 0.7 0.55 10.1 0.0 5.3 6 0 0 6 6 5 2 Rad17 P-loop domain AAA_28 PF13521.6 ORX92053.1 - 2.8e-08 34.2 6.3 1.2 9.3 0.0 6.9 6 0 0 6 6 6 1 AAA domain RsgA_GTPase PF03193.16 ORX92053.1 - 7.8e-08 32.4 0.4 2.9 7.8 0.0 5.9 6 0 0 6 6 5 0 RsgA GTPase TIP49 PF06068.13 ORX92053.1 - 1.5e-07 31.0 1.0 0.013 14.7 0.0 5.6 6 0 0 6 6 5 1 TIP49 P-loop domain PduV-EutP PF10662.9 ORX92053.1 - 2.2e-07 30.7 2.6 0.02 14.7 0.0 5.7 6 0 0 6 6 6 1 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.6 ORX92053.1 - 1.1e-06 28.5 0.4 8.1 6.1 0.0 6.8 6 1 0 6 6 6 0 AAA domain SRP54 PF00448.22 ORX92053.1 - 2.2e-06 27.4 3.1 0.99 9.0 0.0 5.5 6 0 0 6 6 6 2 SRP54-type protein, GTPase domain PhoH PF02562.16 ORX92053.1 - 2.9e-06 26.9 0.1 2.6 7.4 0.0 5.5 6 0 0 6 6 5 1 PhoH-like protein ATPase PF06745.13 ORX92053.1 - 3.1e-06 26.7 0.0 3.5 6.9 0.0 5.3 5 0 0 5 5 4 0 KaiC NTPase_1 PF03266.15 ORX92053.1 - 9.3e-06 25.6 8.1 1.1 9.1 0.1 6.0 6 0 0 6 6 5 1 NTPase SRPRB PF09439.10 ORX92053.1 - 1e-05 25.0 0.1 3.7 6.9 0.0 5.7 5 0 0 5 5 5 0 Signal recognition particle receptor beta subunit Roc PF08477.13 ORX92053.1 - 1.1e-05 25.7 1.1 25 5.1 0.0 5.8 6 0 0 6 6 5 0 Ras of Complex, Roc, domain of DAPkinase DUF815 PF05673.13 ORX92053.1 - 1.2e-05 24.6 0.1 2.6 7.1 0.0 5.0 5 0 0 5 5 5 1 Protein of unknown function (DUF815) TniB PF05621.11 ORX92053.1 - 1.5e-05 24.5 4.9 3.7 6.9 0.0 6.0 7 0 0 7 7 5 0 Bacterial TniB protein Viral_helicase1 PF01443.18 ORX92053.1 - 9.6e-05 22.2 0.0 19 4.9 0.0 5.5 5 0 0 5 5 5 0 Viral (Superfamily 1) RNA helicase MMR_HSR1 PF01926.23 ORX92053.1 - 0.00011 22.3 0.3 45 4.2 0.0 5.9 5 0 0 5 5 5 0 50S ribosome-binding GTPase dNK PF01712.19 ORX92053.1 - 0.00027 20.9 3.3 27 4.5 0.0 5.6 5 0 0 5 5 5 0 Deoxynucleoside kinase cobW PF02492.19 ORX92053.1 - 0.00037 20.1 6.8 2.8 7.5 0.0 6.1 6 0 0 6 6 6 0 CobW/HypB/UreG, nucleotide-binding domain CbiA PF01656.23 ORX92053.1 - 0.00097 19.2 0.0 11 6.1 0.0 5.0 5 0 0 5 5 4 0 CobQ/CobB/MinD/ParA nucleotide binding domain DEAD PF00270.29 ORX92053.1 - 0.0014 18.4 0.1 15 5.3 0.0 5.0 4 0 0 4 4 4 0 DEAD/DEAH box helicase VWA PF00092.28 ORX92053.1 - 0.0016 18.7 0.0 0.0063 16.8 0.0 2.1 2 0 0 2 2 1 1 von Willebrand factor type A domain Bac_DnaA PF00308.18 ORX92053.1 - 0.0018 18.1 0.1 43 3.8 0.0 4.6 5 0 0 5 5 4 0 Bacterial dnaA protein DAP3 PF10236.9 ORX92053.1 - 0.0025 17.0 1.0 3.4 6.7 0.0 4.8 5 0 0 5 5 5 0 Mitochondrial ribosomal death-associated protein 3 Thymidylate_kin PF02223.17 ORX92053.1 - 0.0025 17.5 2.7 0.91 9.2 0.0 4.9 5 0 0 5 5 4 1 Thymidylate kinase DnaB_C PF03796.15 ORX92053.1 - 0.0026 17.2 0.6 4.1 6.7 0.0 4.0 4 0 0 4 4 4 0 DnaB-like helicase C terminal domain KTI12 PF08433.10 ORX92053.1 - 0.0053 16.3 0.0 37 3.6 0.0 5.1 5 0 0 5 5 5 0 Chromatin associated protein KTI12 KAP_NTPase PF07693.14 ORX92053.1 - 0.012 14.8 0.0 5 6.3 0.0 3.7 4 0 0 4 4 3 0 KAP family P-loop domain ATP_bind_1 PF03029.17 ORX92053.1 - 0.032 14.0 12.3 3.3 7.4 0.0 6.6 7 0 0 7 7 7 0 Conserved hypothetical ATP binding protein CPT PF07931.12 ORX92053.1 - 0.044 13.6 1.7 69 3.2 0.1 5.5 5 1 0 5 5 3 0 Chloramphenicol phosphotransferase-like protein TrwB_AAD_bind PF10412.9 ORX92053.1 - 0.048 12.6 1.7 18 4.1 0.0 4.1 5 0 0 5 5 5 0 Type IV secretion-system coupling protein DNA-binding domain FtsK_SpoIIIE PF01580.18 ORX92053.1 - 0.056 12.8 0.1 16 4.7 0.0 4.4 6 0 0 6 6 5 0 FtsK/SpoIIIE family Cytidylate_kin PF02224.18 ORX92053.1 - 0.057 13.2 0.3 24 4.5 0.0 4.2 5 0 0 5 5 5 0 Cytidylate kinase APS_kinase PF01583.20 ORX92053.1 - 0.069 13.0 0.7 16 5.3 0.0 3.9 4 0 0 4 4 3 0 Adenylylsulphate kinase FeoB_N PF02421.18 ORX92053.1 - 0.19 11.2 1.3 37 3.8 0.0 4.1 5 0 0 5 5 3 0 Ferrous iron transport protein B SKI PF01202.22 ORX92053.1 - 0.22 11.6 2.5 12 6.0 0.0 4.2 5 0 0 5 5 2 0 Shikimate kinase MobB PF03205.14 ORX92053.1 - 2.5 8.0 7.7 91 2.9 0.1 5.3 6 0 0 6 6 6 0 Molybdopterin guanine dinucleotide synthesis protein B Gate PF07670.14 ORX92058.1 - 9.1e-06 25.9 2.2 0.029 14.6 1.2 2.4 2 1 0 2 2 2 2 Nucleoside recognition NdhL PF10716.9 ORX92058.1 - 0.17 11.8 2.5 5.5 7.0 0.4 2.7 2 0 0 2 2 2 0 NADH dehydrogenase transmembrane subunit DUF2897 PF11446.8 ORX92058.1 - 0.33 10.8 2.2 4.2 7.3 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2897) adh_short PF00106.25 ORX92059.1 - 4.3e-20 72.0 0.1 1.7e-17 63.5 0.1 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 ORX92059.1 - 1.6e-10 41.0 0.0 8.1e-08 32.1 0.0 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORX92059.1 - 2.3e-08 34.1 0.1 3.9e-08 33.4 0.1 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 ORX92059.1 - 0.0055 15.9 0.0 0.0093 15.1 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DUF3842 PF12953.7 ORX92059.1 - 0.043 14.2 0.4 0.096 13.1 0.1 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF3842) VASP_tetra PF08776.11 ORX92060.1 - 0.14 11.7 1.5 0.34 10.5 1.5 1.6 1 0 0 1 1 1 0 VASP tetramerisation domain MerR-DNA-bind PF09278.11 ORX92060.1 - 7.2 7.2 9.1 35 5.0 1.1 3.3 2 1 1 3 3 3 0 MerR, DNA binding WD40 PF00400.32 ORX92061.1 - 2.5e-24 85.1 14.3 1.3e-05 25.9 0.2 7.3 7 1 1 8 8 8 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX92061.1 - 1.6e-17 63.5 2.2 0.018 15.3 0.0 6.0 2 1 3 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ORX92061.1 - 7.8e-07 29.2 0.6 0.00031 20.7 0.2 2.8 1 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Gmad1 PF10647.9 ORX92061.1 - 0.00045 20.0 0.0 0.067 12.9 0.0 2.6 1 1 1 2 2 2 1 Lipoprotein LpqB beta-propeller domain WD40_like PF17005.5 ORX92061.1 - 0.0046 16.3 1.0 0.0081 15.5 1.0 1.4 1 1 0 1 1 1 1 WD40-like domain PD40 PF07676.12 ORX92061.1 - 0.059 13.3 0.5 1.2e+02 2.7 0.0 4.3 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 ORX92061.1 - 0.25 10.2 5.5 0.47 9.4 2.5 2.7 2 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein F-box PF00646.33 ORX92063.1 - 0.23 11.4 0.7 0.52 10.3 0.7 1.6 1 0 0 1 1 1 0 F-box domain Acyl-CoA_dh_1 PF00441.24 ORX92064.1 - 4.2e-29 101.7 0.1 5.6e-29 101.3 0.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 ORX92064.1 - 1.9e-24 85.7 0.1 3.2e-24 85.0 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 ORX92064.1 - 2.6e-21 76.4 0.1 8.6e-21 74.7 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 ORX92064.1 - 0.06 13.6 0.0 0.094 13.0 0.0 1.2 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.6 ORX92064.1 - 0.07 13.7 0.0 0.15 12.6 0.0 1.5 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal PapJ PF14855.6 ORX92076.1 - 0.072 12.8 0.1 0.11 12.2 0.1 1.2 1 0 0 1 1 1 0 Pilus-assembly fibrillin subunit, chaperone Miga PF10265.9 ORX92076.1 - 0.084 11.8 3.8 0.096 11.6 3.8 1.0 1 0 0 1 1 1 0 Mitoguardin 2OG-FeII_Oxy_3 PF13640.6 ORX92150.1 - 1e-07 32.7 0.0 2e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF4381 PF14316.6 ORX92151.1 - 0.031 14.5 0.1 0.05 13.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) LapA_dom PF06305.11 ORX92151.1 - 0.23 11.3 1.1 0.37 10.6 1.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain CcmD PF04995.14 ORX92151.1 - 0.36 10.9 4.7 0.76 9.9 4.7 1.5 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) Pyr_redox_2 PF07992.14 ORX92173.1 - 2.3e-37 128.8 0.0 3.2e-37 128.4 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORX92173.1 - 1.1e-10 41.9 0.0 2.4e-08 34.4 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.32 ORX92173.1 - 1e-06 27.9 0.3 2.3e-06 26.7 0.3 1.7 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 ORX92173.1 - 8.6e-06 25.3 0.3 3.1e-05 23.6 0.3 2.0 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.6 ORX92173.1 - 9.7e-05 21.7 0.4 0.00023 20.5 0.4 1.7 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 ORX92173.1 - 0.00079 19.8 0.1 0.0022 18.4 0.1 1.8 1 0 0 1 1 1 1 EF-hand domain pair PTPS PF01242.19 ORX92173.1 - 0.0044 17.0 0.1 0.25 11.3 0.0 2.9 3 0 0 3 3 3 1 6-pyruvoyl tetrahydropterin synthase WD40 PF00400.32 ORX92174.1 - 1.8e-29 101.3 11.5 4.7e-06 27.2 0.3 5.9 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.8 ORX92174.1 - 1.4e-08 33.8 3.9 0.15 10.7 0.1 5.0 4 1 1 5 5 5 5 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 ORX92174.1 - 8.7e-07 29.2 0.1 1.3 9.4 0.0 4.8 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain MscS_porin PF12795.7 ORX92174.1 - 0.0017 17.9 1.2 0.003 17.1 1.2 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain BBS2_Mid PF14783.6 ORX92174.1 - 0.0046 17.0 0.0 0.048 13.7 0.0 2.8 4 0 0 4 4 4 1 Ciliary BBSome complex subunit 2, middle region Baculo_p24 PF05073.12 ORX92174.1 - 0.0088 15.8 0.4 0.014 15.2 0.1 1.4 2 0 0 2 2 2 1 Baculovirus P24 capsid protein APG6_N PF17675.1 ORX92174.1 - 0.015 15.8 1.9 0.028 14.9 1.9 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF5046 PF16465.5 ORX92174.1 - 0.038 13.4 0.5 0.95 8.9 0.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5046) Herpes_UL14 PF03580.14 ORX92174.1 - 0.04 14.1 0.6 0.078 13.2 0.6 1.4 1 0 0 1 1 1 0 Herpesvirus UL14-like protein CENP-F_leu_zip PF10473.9 ORX92174.1 - 0.086 12.9 2.4 0.18 11.8 2.4 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Osmo_CC PF08946.10 ORX92174.1 - 2.5 8.4 5.3 17 5.7 1.2 2.6 2 0 0 2 2 2 0 Osmosensory transporter coiled coil ALG3 PF05208.13 ORX92176.1 - 2.2e-140 468.2 8.3 2.5e-140 468.0 8.3 1.0 1 0 0 1 1 1 1 ALG3 protein eIF-1a PF01176.19 ORX92177.1 - 9.7e-19 66.9 0.1 1.3e-18 66.5 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 T4_tail_cap PF11091.8 ORX92177.1 - 0.12 11.2 0.0 0.16 10.9 0.0 1.1 1 0 0 1 1 1 0 Tail-tube assembly protein MFS_1 PF07690.16 ORX92178.1 - 1.2e-16 60.6 14.4 1.5e-16 60.3 14.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORX92178.1 - 0.15 10.9 12.6 0.21 10.4 12.6 1.1 1 0 0 1 1 1 0 Sugar (and other) transporter Glyoxalase PF00903.25 ORX92184.1 - 0.0096 16.1 0.1 0.069 13.3 0.1 1.9 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Methyltransf_11 PF08241.12 ORX92185.1 - 2.9e-10 40.6 0.0 5e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORX92185.1 - 2.2e-09 37.9 0.0 3.8e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORX92185.1 - 1e-05 25.4 0.0 2e-05 24.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORX92185.1 - 2.2e-05 24.3 0.0 2.9e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORX92185.1 - 2.3e-05 25.0 0.0 4.6e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DnaB_bind PF10410.9 ORX92185.1 - 0.0099 16.0 0.0 0.019 15.2 0.0 1.5 1 0 0 1 1 1 1 DnaB-helicase binding domain of primase LYTB PF02401.18 ORX92185.1 - 0.015 14.6 0.0 0.02 14.1 0.0 1.1 1 0 0 1 1 1 0 LytB protein CPBP PF02517.16 ORX92186.1 - 3.5e-16 59.3 9.9 3.5e-16 59.3 9.9 3.2 3 1 0 3 3 3 1 CPBP intramembrane metalloprotease eIF-6 PF01912.18 ORX92188.1 - 1.4e-79 266.1 1.5 1.8e-79 265.7 1.5 1.2 1 0 0 1 1 1 1 eIF-6 family Es2 PF09751.9 ORX92189.1 - 5e-115 385.7 2.3 5.9e-115 385.5 2.3 1.0 1 0 0 1 1 1 1 Nuclear protein Es2 DEAD PF00270.29 ORX92235.1 - 1.8e-17 63.7 0.0 3.5e-17 62.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 ORX92235.1 - 3.5e-12 46.7 0.0 1.1e-11 45.0 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 ORX92235.1 - 2.4e-08 34.3 0.1 7.8e-08 32.6 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SulA PF03846.14 ORX92235.1 - 0.09 12.7 0.1 0.23 11.4 0.1 1.6 1 0 0 1 1 1 0 Cell division inhibitor SulA Esterase_phd PF10503.9 ORX92236.1 - 1.1e-21 77.4 0.1 1.4e-21 77.0 0.1 1.1 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 ORX92236.1 - 1.6e-08 34.3 0.2 2.4e-08 33.7 0.2 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.28 ORX92236.1 - 0.0042 16.0 0.1 0.0076 15.2 0.1 1.3 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 ORX92236.1 - 0.016 15.1 0.0 0.033 14.1 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold SET PF00856.28 ORX92239.1 - 0.051 14.0 0.0 0.064 13.6 0.0 1.3 1 0 0 1 1 1 0 SET domain Pkinase PF00069.25 ORX92290.1 - 8.8e-66 222.0 0.0 1e-65 221.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX92290.1 - 4.6e-25 88.4 0.0 5.8e-25 88.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORX92290.1 - 3.2e-06 26.7 0.0 1.3e-05 24.7 0.0 1.8 1 1 0 2 2 2 1 Kinase-like APH PF01636.23 ORX92290.1 - 0.0021 18.0 0.0 0.0075 16.2 0.0 1.7 1 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 ORX92290.1 - 0.12 11.7 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2015 PF09435.10 ORX92292.1 - 5.6e-45 151.8 0.0 6.4e-45 151.6 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) Ribosomal_L28e PF01778.17 ORX92293.1 - 1.2e-29 103.4 1.0 1.6e-29 103.0 1.0 1.2 1 0 0 1 1 1 1 Ribosomal L28e protein family RRM_1 PF00076.22 ORX92294.1 - 2e-34 117.2 0.0 4.8e-17 61.5 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 ORX92294.1 - 1.3e-05 24.8 0.0 0.18 11.4 0.0 2.2 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 ORX92294.1 - 0.00019 21.5 0.0 0.00093 19.3 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif OB_RNB PF08206.11 ORX92294.1 - 0.0034 17.0 0.9 0.98 9.2 0.1 2.4 2 0 0 2 2 2 2 Ribonuclease B OB domain Cas_Cas2CT1978 PF09707.10 ORX92294.1 - 0.0056 16.7 0.0 1.9 8.6 0.0 2.3 2 0 0 2 2 2 2 CRISPR-associated protein (Cas_Cas2CT1978) Limkain-b1 PF11608.8 ORX92294.1 - 0.03 14.4 0.0 2.8 8.1 0.0 2.2 2 0 0 2 2 2 0 Limkain b1 CMV_1a_C PF12503.8 ORX92294.1 - 0.031 14.3 0.2 5 7.2 0.2 2.7 2 1 1 3 3 3 0 Cucumber mosaic virus 1a protein C terminal Tom7 PF08038.12 ORX92295.1 - 9.6e-22 76.4 0.1 1.2e-21 76.1 0.1 1.1 1 0 0 1 1 1 1 TOM7 family WD40 PF00400.32 ORX92357.1 - 6.9e-15 55.2 5.9 0.00079 20.2 0.1 4.9 4 0 0 4 4 4 4 WD domain, G-beta repeat Glycos_transf_4 PF00953.21 ORX92358.1 - 5.2e-33 114.3 11.7 5.2e-33 114.3 11.7 2.0 2 1 0 2 2 2 1 Glycosyl transferase family 4 SPC12 PF06645.13 ORX92358.1 - 0.73 10.0 4.1 0.5 10.5 0.4 2.7 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) Aconitase PF00330.20 ORX92359.1 - 5.8e-162 539.9 0.0 7e-162 539.6 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 ORX92359.1 - 1.3e-40 138.7 0.0 2.5e-40 137.8 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF4215 PF13948.6 ORX92361.1 - 0.00015 22.1 6.4 0.00015 22.1 6.4 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4215) Pkinase PF00069.25 ORX92387.1 - 7.1e-10 38.7 0.0 1e-09 38.1 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX92387.1 - 4.5e-08 32.7 0.1 1.2e-07 31.3 0.1 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 ORX92387.1 - 0.00035 20.0 0.1 0.00043 19.7 0.1 1.2 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 ORX92387.1 - 0.018 14.3 0.0 0.13 11.5 0.0 1.9 1 1 0 1 1 1 0 Kinase-like adh_short PF00106.25 ORX92395.1 - 2.1e-21 76.3 0.3 2.1e-19 69.7 0.3 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 ORX92395.1 - 2.5e-11 43.6 0.1 3.8e-10 39.7 0.1 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORX92395.1 - 7.6e-09 35.7 0.2 1.1e-08 35.2 0.2 1.2 1 0 0 1 1 1 1 KR domain FAD_binding_4 PF01565.23 ORX92396.1 - 1.2e-21 76.9 3.9 3e-21 75.6 3.9 1.7 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 ORX92396.1 - 1.3e-10 41.2 0.9 2.9e-10 40.1 0.9 1.5 1 0 0 1 1 1 1 Berberine and berberine like CFEM PF05730.11 ORX92397.1 - 1.4e-08 34.7 10.5 1.4e-08 34.7 10.5 2.1 2 0 0 2 2 2 1 CFEM domain Bax1-I PF01027.20 ORX92420.1 - 0.1 12.4 2.4 0.34 10.7 0.0 2.1 1 1 2 3 3 3 0 Inhibitor of apoptosis-promoting Bax1 Cation_efflux PF01545.21 ORX92420.1 - 0.11 12.2 1.0 0.26 11.0 0.0 2.0 2 1 1 3 3 3 0 Cation efflux family DUF1772 PF08592.11 ORX92420.1 - 0.2 11.9 0.2 0.2 11.9 0.2 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF1772) Myb_DNA-binding PF00249.31 ORX92421.1 - 1.1e-12 48.0 2.0 1e-10 41.6 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORX92421.1 - 7.3e-06 26.1 2.7 0.00031 20.9 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain AGOG PF09171.10 ORX92421.1 - 0.031 13.6 0.1 0.033 13.5 0.1 1.2 1 0 0 1 1 1 0 N-glycosylase/DNA lyase Imm31 PF15591.6 ORX92421.1 - 0.037 13.9 0.4 8.3 6.3 0.0 2.2 2 0 0 2 2 2 0 Immunity protein 31 DUF2841 PF11001.8 ORX92422.1 - 6.3e-09 35.9 0.0 1.1e-08 35.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) INO80_Ies4 PF08193.11 ORX92422.1 - 0.48 10.4 11.0 0.82 9.6 11.0 1.3 1 0 0 1 1 1 0 INO80 complex subunit Ies4 TRAM_LAG1_CLN8 PF03798.16 ORX92435.1 - 9.7e-36 123.4 24.5 9.7e-36 123.4 24.5 1.8 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 ORX92435.1 - 5.4e-22 77.2 0.0 5.4e-22 77.2 0.0 2.5 3 0 0 3 3 3 1 TRAM1-like protein VPS38 PF17649.1 ORX92436.1 - 3.9e-15 55.7 0.0 2.4e-08 33.3 0.0 3.9 3 1 1 4 4 4 3 Vacuolar protein sorting 38 Atg14 PF10186.9 ORX92436.1 - 9.5e-14 51.2 12.6 4.7e-13 48.9 12.6 1.9 1 1 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 APG6 PF04111.12 ORX92436.1 - 0.045 13.7 0.0 0.086 12.8 0.0 1.4 1 0 0 1 1 1 0 Apg6 BARA domain Exonuc_VII_L PF02601.15 ORX92436.1 - 0.17 11.4 5.6 0.32 10.5 5.6 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit Spc7 PF08317.11 ORX92436.1 - 0.84 8.5 17.5 1.3 7.8 17.5 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein ATG16 PF08614.11 ORX92436.1 - 0.97 9.6 21.3 0.13 12.5 14.8 2.2 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) FIVAR PF07554.13 ORX92436.1 - 1 10.2 3.9 0.36 11.6 0.4 2.0 2 0 0 2 2 2 0 FIVAR domain DUF4407 PF14362.6 ORX92436.1 - 1.1 8.6 7.5 1.8 7.8 7.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ZYG-11_interact PF05884.12 ORX92436.1 - 1.4 8.3 2.6 7.1 5.9 0.6 2.1 1 1 1 2 2 2 0 Interactor of ZYG-11 DUF1664 PF07889.12 ORX92436.1 - 2.8 8.0 13.6 3.7 7.6 7.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Mhr1 PF12829.7 ORX92437.1 - 4.9e-26 90.6 0.6 2e-25 88.6 0.0 2.4 2 0 0 2 2 2 1 Transcriptional regulation of mitochondrial recombination FTA4 PF13093.6 ORX92438.1 - 1.8e-45 155.3 0.0 2.1e-45 155.1 0.0 1.0 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Nop14 PF04147.12 ORX92439.1 - 2.2 6.4 19.1 3 6.0 19.1 1.1 1 0 0 1 1 1 0 Nop14-like family TFIIF_alpha PF05793.12 ORX92439.1 - 5 5.6 23.5 10 4.6 23.5 1.5 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Apt1 PF10351.9 ORX92439.1 - 9.2 5.0 8.0 12 4.6 8.0 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain Fungal_lectin PF07938.12 ORX92440.1 - 5e-05 22.8 1.5 0.00049 19.6 0.4 1.9 1 1 0 2 2 2 1 Fungal fucose-specific lectin Piwi PF02171.17 ORX92441.1 - 3.7e-20 72.4 0.0 4.7e-20 72.0 0.0 1.1 1 0 0 1 1 1 1 Piwi domain Piwi PF02171.17 ORX92442.1 - 1.9e-16 60.2 0.1 2.1e-16 60.0 0.1 1.0 1 0 0 1 1 1 1 Piwi domain SIKE PF05769.11 ORX92443.1 - 1.3e-10 41.5 3.4 1.7e-10 41.1 3.4 1.1 1 0 0 1 1 1 1 SIKE family DivIC PF04977.15 ORX92443.1 - 0.0033 17.2 5.1 0.058 13.2 0.2 3.4 3 1 0 3 3 3 2 Septum formation initiator Lebercilin PF15619.6 ORX92443.1 - 0.025 14.2 8.1 0.44 10.2 0.2 2.9 2 1 0 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease DUF4357 PF14267.6 ORX92443.1 - 0.46 10.5 6.5 5.2 7.1 4.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4357) BRE1 PF08647.11 ORX92443.1 - 4.5 7.4 8.6 1.4 9.1 0.1 3.2 4 0 0 4 4 4 0 BRE1 E3 ubiquitin ligase PMI_typeI PF01238.21 ORX92444.1 - 9.9e-146 485.7 0.0 1.2e-145 485.5 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I Cas_TM1802 PF09484.10 ORX92444.1 - 0.00081 18.3 0.1 0.001 18.0 0.1 1.1 1 0 0 1 1 1 1 CRISPR-associated protein TM1802 (cas_TM1802) RraB PF06877.11 ORX92444.1 - 0.22 12.2 1.8 0.46 11.2 0.6 2.1 2 0 0 2 2 2 0 Regulator of ribonuclease activity B APH PF01636.23 ORX92461.1 - 6.2e-08 32.9 0.1 1.9e-07 31.2 0.1 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 ORX92461.1 - 1.4e-07 31.4 0.0 2e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.11 ORX92461.1 - 0.00059 18.8 0.0 0.00092 18.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) Pkinase PF00069.25 ORX92461.1 - 0.0012 18.3 0.0 0.13 11.6 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain EcKinase PF02958.20 ORX92461.1 - 0.024 13.9 0.0 0.038 13.3 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase Kdo PF06293.14 ORX92461.1 - 0.15 11.4 0.0 0.42 9.9 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Fig1 PF12351.8 ORX92463.1 - 1.5e-18 67.4 3.4 2.1e-18 66.9 3.4 1.1 1 0 0 1 1 1 1 Ca2+ regulator and membrane fusion protein Fig1 TPPK_C PF12555.8 ORX92463.1 - 0.5 10.5 4.6 14 5.8 0.3 2.5 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal SUR7 PF06687.12 ORX92463.1 - 0.52 9.9 9.1 0.98 9.0 9.1 1.6 1 1 0 1 1 1 0 SUR7/PalI family p450 PF00067.22 ORX92482.1 - 1.1e-40 139.8 0.1 1.2e-40 139.6 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 ORX92483.1 - 2.5e-45 155.1 0.0 3e-45 154.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Arylesterase PF01731.20 ORX92492.1 - 0.0015 18.7 0.1 0.0085 16.3 0.1 2.1 2 0 0 2 2 2 1 Arylesterase GMC_oxred_N PF00732.19 ORX92493.1 - 1.6e-61 208.3 0.0 2.1e-61 207.9 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 ORX92493.1 - 7e-31 107.7 0.0 1.2e-30 106.9 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 ORX92493.1 - 7.8e-05 21.9 0.5 0.079 12.0 0.4 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 ORX92493.1 - 0.00016 20.9 0.1 0.00043 19.4 0.0 1.9 3 0 0 3 3 3 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 ORX92493.1 - 0.0037 16.5 0.1 0.12 11.6 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORX92493.1 - 0.0071 16.5 0.2 0.024 14.9 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ORX92493.1 - 0.014 15.0 1.5 0.27 10.8 0.8 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase Thi4 PF01946.17 ORX92493.1 - 0.029 13.6 0.1 0.05 12.8 0.1 1.3 1 0 0 1 1 1 0 Thi4 family TrkA_N PF02254.18 ORX92493.1 - 0.057 13.7 0.0 0.52 10.6 0.0 2.3 2 0 0 2 2 2 0 TrkA-N domain Pyr_redox_3 PF13738.6 ORX92493.1 - 0.12 11.6 0.6 12 5.0 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NIBRIN_BRCT_II PF16508.5 ORX92495.1 - 2.3e-30 105.3 0.0 1.3e-29 103.0 0.0 2.4 2 0 0 2 2 2 1 Second BRCT domain on Nijmegen syndrome breakage protein FHA PF00498.26 ORX92495.1 - 5.3e-05 23.5 0.0 0.00011 22.5 0.0 1.5 1 0 0 1 1 1 1 FHA domain RTT107_BRCT_5 PF16770.5 ORX92495.1 - 0.0016 18.3 0.0 0.0061 16.4 0.0 2.0 2 0 0 2 2 2 1 Regulator of Ty1 transposition protein 107 BRCT domain Terminase_2 PF03592.16 ORX92495.1 - 0.019 15.4 0.4 0.046 14.2 0.4 1.6 1 0 0 1 1 1 0 Terminase small subunit PTCB-BRCT PF12738.7 ORX92495.1 - 0.036 14.0 0.3 0.076 13.0 0.3 1.5 1 0 0 1 1 1 0 twin BRCT domain Glyco_hydro_61 PF03443.14 ORX92496.1 - 9.1e-66 221.7 0.2 1.1e-65 221.4 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 MG2 PF01835.19 ORX92496.1 - 0.057 13.9 0.0 0.17 12.4 0.0 1.9 1 1 0 1 1 1 0 MG2 domain UbiA PF01040.18 ORX92497.1 - 1.5e-59 201.4 16.2 1.5e-59 201.4 16.2 1.5 1 1 0 1 1 1 1 UbiA prenyltransferase family RPN2_C PF18004.1 ORX92498.1 - 6.1e-56 188.8 7.7 6.1e-56 188.8 7.7 2.0 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 ORX92498.1 - 3.7e-33 112.3 17.1 5.2e-10 39.2 0.0 8.4 8 0 0 8 8 8 6 Proteasome/cyclosome repeat HEAT_2 PF13646.6 ORX92498.1 - 1.2e-18 67.3 0.5 8.2e-14 51.8 0.0 4.5 5 1 2 7 7 7 3 HEAT repeats HEAT_EZ PF13513.6 ORX92498.1 - 6.8e-06 26.5 0.1 0.0084 16.6 0.0 4.0 2 1 1 3 3 3 1 HEAT-like repeat HEAT PF02985.22 ORX92498.1 - 0.00049 20.1 2.2 9.8 6.8 0.0 5.5 5 0 0 5 5 5 1 HEAT repeat ANAPC3 PF12895.7 ORX92498.1 - 0.048 13.9 0.1 13 6.1 0.1 2.8 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Cnd1 PF12717.7 ORX92498.1 - 0.06 13.4 2.4 0.91 9.5 0.1 3.2 3 1 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 TPR_19 PF14559.6 ORX92498.1 - 0.16 12.5 0.3 62 4.2 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat mRNA_triPase PF02940.15 ORX92499.1 - 4.8e-49 167.0 0.2 6.1e-49 166.7 0.2 1.1 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain CREPT PF16566.5 ORX92499.1 - 0.016 15.4 0.1 0.043 14.0 0.1 1.6 1 1 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour PK PF00224.21 ORX92500.1 - 1e-170 567.2 3.5 1.2e-170 567.0 3.5 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 ORX92500.1 - 3.1e-38 130.6 0.0 8.3e-38 129.2 0.0 1.8 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 ORX92500.1 - 0.0008 18.6 0.2 0.0024 17.1 0.1 1.8 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.25 ORX92500.1 - 0.0097 14.9 0.0 0.045 12.8 0.0 2.0 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain NACHT PF05729.12 ORX92514.1 - 1.8e-10 41.0 0.0 1.1e-09 38.5 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 ORX92514.1 - 1.8e-09 38.2 1.4 1.4e-07 32.0 0.0 3.7 3 2 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 ORX92514.1 - 3.1e-05 24.3 0.0 0.00037 20.8 0.0 2.9 2 0 0 2 2 2 1 AAA domain SesA PF17107.5 ORX92514.1 - 8.2e-05 22.8 0.5 0.00069 19.8 0.0 2.8 2 1 0 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases ATPase_2 PF01637.18 ORX92514.1 - 0.0017 18.3 0.1 0.0072 16.3 0.0 2.1 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea KAP_NTPase PF07693.14 ORX92514.1 - 0.0031 16.8 0.3 3.7 6.7 0.0 3.1 3 0 0 3 3 3 2 KAP family P-loop domain RNA_helicase PF00910.22 ORX92514.1 - 0.0068 16.8 0.1 0.02 15.3 0.1 1.8 1 0 0 1 1 1 1 RNA helicase AAA_30 PF13604.6 ORX92514.1 - 0.018 14.8 0.0 0.076 12.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 ORX92514.1 - 0.018 15.6 0.6 0.078 13.5 0.0 2.4 2 0 0 2 2 2 0 ABC transporter AAA_29 PF13555.6 ORX92514.1 - 0.021 14.5 0.0 0.1 12.4 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA PF00004.29 ORX92514.1 - 0.028 14.8 0.0 1.5 9.2 0.0 3.5 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 ORX92514.1 - 0.068 13.7 0.0 0.31 11.6 0.0 2.1 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 ORX92514.1 - 0.096 12.6 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase VWA_2 PF13519.6 ORX92514.1 - 0.11 13.2 0.2 15 6.2 0.0 3.8 2 1 0 3 3 3 0 von Willebrand factor type A domain cobW PF02492.19 ORX92514.1 - 0.14 11.7 0.0 0.34 10.5 0.0 1.7 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain DUF87 PF01935.17 ORX92514.1 - 0.15 12.2 5.7 0.66 10.0 0.0 3.5 3 1 0 3 3 3 0 Helicase HerA, central domain Sec5 PF15469.6 ORX92514.1 - 0.22 11.3 4.2 0.58 9.9 4.2 1.7 1 0 0 1 1 1 0 Exocyst complex component Sec5 AAA_23 PF13476.6 ORX92514.1 - 0.64 10.5 0.0 0.64 10.5 0.0 3.1 2 1 0 2 2 1 0 AAA domain zf-dskA_traR PF01258.17 ORX92515.1 - 0.019 14.9 1.1 0.04 13.9 1.1 1.5 1 0 0 1 1 1 0 Prokaryotic dksA/traR C4-type zinc finger COX4_pro_2 PF07835.12 ORX92516.1 - 0.19 11.8 0.1 0.19 11.8 0.1 1.8 2 0 0 2 2 2 0 Bacterial aa3 type cytochrome c oxidase subunit IV CHAT PF12770.7 ORX92518.1 - 1.5e-33 116.5 0.0 2.5e-33 115.8 0.0 1.3 1 0 0 1 1 1 1 CHAT domain TPR_10 PF13374.6 ORX92518.1 - 3.2e-06 26.8 3.8 0.041 13.8 0.0 5.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 ORX92518.1 - 0.00012 22.3 8.5 3.5 8.0 0.1 6.5 8 0 0 8 8 8 3 Tetratricopeptide repeat SMBP PF16785.5 ORX92518.1 - 0.16 12.2 0.1 3.8 7.8 0.0 2.6 2 0 0 2 2 2 0 Small metal-binding protein Spore_SspJ PF09575.10 ORX92518.1 - 0.29 11.5 1.6 26 5.3 0.2 2.8 2 0 0 2 2 2 0 Small spore protein J (Spore_SspJ) Pkinase_Tyr PF07714.17 ORX92519.1 - 4.9e-17 62.1 0.0 6.6e-17 61.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 ORX92519.1 - 1.5e-15 57.3 0.0 2e-15 56.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain AA_permease_2 PF13520.6 ORX92544.1 - 9.5e-47 159.8 29.8 3.6e-41 141.4 22.8 2.1 1 1 1 2 2 2 2 Amino acid permease AA_permease PF00324.21 ORX92544.1 - 1.4e-08 33.8 29.1 2.4e-08 33.0 29.1 1.3 1 1 0 1 1 1 1 Amino acid permease Cerato-platanin PF07249.12 ORX92545.1 - 0.0009 19.4 0.1 0.0023 18.0 0.1 1.7 1 0 0 1 1 1 1 Cerato-platanin SKG6 PF08693.10 ORX92545.1 - 0.008 15.6 0.7 0.015 14.7 0.7 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain VSP PF03302.13 ORX92545.1 - 0.014 14.2 3.4 0.023 13.5 3.4 1.3 1 0 0 1 1 1 0 Giardia variant-specific surface protein MLANA PF14991.6 ORX92545.1 - 0.016 15.5 0.0 0.03 14.6 0.0 1.4 1 0 0 1 1 1 0 Protein melan-A PTP_tm PF18861.1 ORX92545.1 - 0.024 14.6 0.4 0.044 13.8 0.4 1.4 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J TMEM190 PF15431.6 ORX92545.1 - 0.087 13.0 0.0 0.33 11.1 0.0 1.9 2 0 0 2 2 2 0 Transmembrane protein 190 DUF4448 PF14610.6 ORX92545.1 - 0.13 12.0 0.0 0.19 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Ank_2 PF12796.7 ORX92547.1 - 9.3e-12 45.4 0.0 1.2e-05 25.8 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORX92547.1 - 2.4e-10 40.7 0.0 8.7e-06 26.2 0.0 3.1 1 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORX92547.1 - 2.6e-08 33.5 0.0 0.15 12.7 0.0 3.7 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 ORX92547.1 - 3.8e-06 27.1 0.1 0.89 10.1 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 ORX92547.1 - 2.1e-05 24.7 0.0 1.2 9.5 0.0 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) DUF5564 PF17719.1 ORX92547.1 - 0.12 12.6 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5564) HET PF06985.11 ORX92548.1 - 5.4e-27 94.9 1.6 2.4e-26 92.8 1.6 2.0 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HET PF06985.11 ORX92549.1 - 3.4e-25 89.1 0.2 6.6e-25 88.2 0.2 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Rsa3 PF14615.6 ORX92551.1 - 1.1e-17 63.3 0.0 1.7e-17 62.7 0.0 1.3 1 0 0 1 1 1 1 Ribosome-assembly protein 3 SR-25 PF10500.9 ORX92551.1 - 0.038 13.6 20.1 0.051 13.2 20.1 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Zip PF02535.22 ORX92551.1 - 0.13 11.5 3.3 0.16 11.1 3.3 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter CDC45 PF02724.14 ORX92551.1 - 0.91 7.7 8.6 0.95 7.7 8.6 1.1 1 0 0 1 1 1 0 CDC45-like protein NPR3 PF03666.13 ORX92551.1 - 1.6 7.4 9.7 1.7 7.4 9.7 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Presenilin PF01080.17 ORX92551.1 - 3.2 6.4 7.8 3.5 6.3 7.8 1.1 1 0 0 1 1 1 0 Presenilin Ndc1_Nup PF09531.10 ORX92551.1 - 6.8 5.2 5.3 6.4 5.3 5.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TPR_16 PF13432.6 ORX92552.1 - 2.6e-06 28.0 1.9 7.9e-05 23.2 0.1 2.7 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 ORX92552.1 - 3.4e-06 26.8 0.1 0.004 17.3 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_22 PF18833.1 ORX92552.1 - 5.6e-06 26.4 0.0 1.2e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 ORX92552.1 - 1.7e-05 25.3 1.5 0.0005 20.7 0.1 3.2 2 2 2 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 ORX92552.1 - 5.4e-05 22.8 0.0 0.00014 21.5 0.0 1.8 1 0 0 1 1 1 1 TPR repeat TPR_2 PF07719.17 ORX92552.1 - 0.00085 19.3 0.7 0.015 15.4 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 ORX92552.1 - 0.0019 18.7 0.5 0.086 13.4 0.1 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 ORX92552.1 - 0.012 15.5 0.1 0.042 13.7 0.1 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_7 PF13176.6 ORX92552.1 - 0.11 12.5 0.1 2.1 8.6 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 ORX92553.1 - 3.7e-27 92.7 3.6 0.0061 16.9 0.0 12.7 13 0 0 13 13 13 5 Tetratricopeptide repeat TPR_1 PF00515.28 ORX92553.1 - 9e-27 91.8 31.3 8e-06 25.5 0.0 13.1 14 0 0 14 14 14 6 Tetratricopeptide repeat TPR_2 PF07719.17 ORX92553.1 - 6.8e-26 88.3 54.1 8e-05 22.5 0.0 16.8 17 0 0 17 17 17 7 Tetratricopeptide repeat TPR_8 PF13181.6 ORX92553.1 - 1.4e-19 68.6 31.8 0.012 15.8 0.0 12.4 14 0 0 14 14 13 6 Tetratricopeptide repeat TPR_14 PF13428.6 ORX92553.1 - 3e-19 68.1 30.3 0.39 11.7 0.1 14.4 10 5 4 14 14 13 5 Tetratricopeptide repeat TPR_11 PF13414.6 ORX92553.1 - 5.2e-15 54.9 13.6 0.0033 17.1 0.0 10.1 10 1 1 11 11 11 4 TPR repeat TPR_12 PF13424.6 ORX92553.1 - 2.1e-14 53.5 44.4 0.052 13.8 0.1 12.4 12 4 3 15 15 15 6 Tetratricopeptide repeat TPR_16 PF13432.6 ORX92553.1 - 4.8e-13 49.5 40.6 0.0038 17.8 0.0 13.1 10 5 4 14 14 14 3 Tetratricopeptide repeat TPR_19 PF14559.6 ORX92553.1 - 4.8e-13 49.4 25.9 5.2e-05 23.7 0.9 11.1 10 2 1 11 11 11 3 Tetratricopeptide repeat TPR_7 PF13176.6 ORX92553.1 - 4.2e-12 45.2 22.3 0.083 12.9 0.0 11.7 11 1 1 12 12 12 2 Tetratricopeptide repeat TPR_20 PF14561.6 ORX92553.1 - 0.0005 20.4 7.1 8 6.9 0.0 6.9 6 2 1 7 7 7 1 Tetratricopeptide repeat TPR_6 PF13174.6 ORX92553.1 - 0.0022 18.5 32.6 3.5 8.5 0.0 12.8 15 0 0 15 15 14 1 Tetratricopeptide repeat TPR_9 PF13371.6 ORX92553.1 - 0.0065 16.6 20.9 1.1 9.4 0.0 8.2 10 1 1 11 11 7 1 Tetratricopeptide repeat DUF4192 PF13830.6 ORX92553.1 - 0.016 15.3 7.9 0.092 12.8 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4192) HrpB1_HrpK PF09613.10 ORX92553.1 - 0.019 14.6 1.5 2.2 8.0 0.0 3.7 4 0 0 4 4 4 0 Bacterial type III secretion protein (HrpB1_HrpK) ChAPs PF09295.10 ORX92553.1 - 0.063 12.3 0.1 15 4.5 0.0 4.4 6 0 0 6 6 6 0 ChAPs (Chs5p-Arf1p-binding proteins) FAT PF02259.23 ORX92553.1 - 0.16 11.2 3.4 12 5.0 0.0 3.5 4 0 0 4 4 4 0 FAT domain DUF627 PF04781.12 ORX92553.1 - 1.6 8.8 6.3 2.9 8.0 0.0 4.2 5 1 0 5 5 4 0 Protein of unknown function (DUF627) Sel1 PF08238.12 ORX92553.1 - 3.6 8.4 6.9 58 4.6 0.0 4.5 6 0 0 6 6 3 0 Sel1 repeat Ank_2 PF12796.7 ORX92554.1 - 3.7e-34 117.2 0.6 9.7e-14 51.7 0.7 5.4 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ORX92554.1 - 1.7e-27 95.1 7.9 9.5e-09 35.4 0.3 6.5 6 0 0 6 6 6 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 ORX92554.1 - 2.4e-26 91.7 8.0 8.6e-06 26.2 0.4 6.7 3 1 3 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORX92554.1 - 3.2e-22 76.2 6.1 0.0023 18.3 0.0 7.6 7 0 0 7 7 7 6 Ankyrin repeat Ank PF00023.30 ORX92554.1 - 3.3e-21 74.7 11.2 0.0036 17.7 0.1 7.7 7 0 0 7 7 7 7 Ankyrin repeat Helo_like_N PF17111.5 ORX92554.1 - 3.1e-06 26.7 1.8 5.2e-06 26.0 1.8 1.4 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins SesA PF17107.5 ORX92554.1 - 0.16 12.2 1.1 0.76 10.0 1.1 2.2 1 1 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases COG2 PF06148.11 ORX92554.1 - 1.4 9.0 5.1 1.4 9.0 0.2 2.4 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 FA_desaturase PF00487.24 ORX92555.1 - 9.1e-34 117.4 20.1 1.4e-33 116.8 20.1 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 ORX92555.1 - 4.7e-10 39.5 0.0 8.4e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Mito_fiss_reg PF05308.11 ORX92566.1 - 7.4 6.6 11.7 11 6.0 11.7 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator Pheromone PF08015.11 ORX92566.1 - 7.5 7.7 16.3 0.95 10.5 11.8 1.8 2 0 0 2 2 2 0 Fungal mating-type pheromone zf-RING_5 PF14634.6 ORX92623.1 - 0.01 15.7 0.4 0.01 15.7 0.4 2.5 2 0 0 2 2 2 0 zinc-RING finger domain zf-RING_2 PF13639.6 ORX92623.1 - 0.012 16.0 1.1 0.012 16.0 1.1 3.1 4 0 0 4 4 4 0 Ring finger domain ATP-synt_E_2 PF08112.11 ORX92624.1 - 0.065 13.5 0.0 0.22 11.8 0.0 1.9 1 0 0 1 1 1 0 ATP synthase epsilon subunit Vps23_core PF09454.10 ORX92624.1 - 0.16 11.9 0.1 9.3 6.3 0.0 2.5 2 0 0 2 2 2 0 Vps23 core domain FRQ PF09421.10 ORX92625.1 - 1.9e-133 446.7 55.3 4.4e-132 442.1 55.3 2.5 1 1 0 1 1 1 1 Frequency clock protein DUF3748 PF12566.8 ORX92625.1 - 0.053 13.5 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3748) PTS_2-RNA PF01885.16 ORX92625.1 - 0.11 12.5 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 RNA 2'-phosphotransferase, Tpt1 / KptA family COQ9 PF08511.11 ORX92626.1 - 2.6e-34 116.8 0.2 3.8e-34 116.3 0.2 1.2 1 0 0 1 1 1 1 COQ9 WD40 PF00400.32 ORX92627.1 - 1.6e-10 41.4 3.4 0.15 13.0 0.0 4.9 5 0 0 5 5 5 4 WD domain, G-beta repeat DUF167 PF02594.16 ORX92629.1 - 6.3e-19 67.9 1.6 1e-18 67.2 1.6 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YggU family COG1872 RTA1 PF04479.13 ORX92630.1 - 0.003 17.2 6.2 0.0059 16.2 6.2 1.4 1 0 0 1 1 1 1 RTA1 like protein TctB PF07331.11 ORX92630.1 - 6.4 7.1 12.9 33 4.8 12.9 2.2 1 1 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family Methyltransf_2 PF00891.18 ORX92631.1 - 1.6e-21 76.6 0.0 1e-20 74.0 0.1 2.2 2 1 0 2 2 2 1 O-methyltransferase domain Dimerisation PF08100.11 ORX92631.1 - 0.00091 19.2 0.0 0.0022 18.0 0.0 1.7 1 0 0 1 1 1 1 Dimerisation domain Dimerisation2 PF16864.5 ORX92631.1 - 0.0026 17.7 0.0 0.0064 16.4 0.0 1.6 1 0 0 1 1 1 1 Dimerisation domain Rrf2 PF02082.20 ORX92631.1 - 0.025 14.9 0.0 0.051 13.9 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator HTH_Crp_2 PF13545.6 ORX92631.1 - 0.027 14.4 0.0 0.088 12.8 0.0 1.8 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain FeoC PF09012.10 ORX92631.1 - 0.039 14.0 0.0 0.1 12.7 0.0 1.7 1 0 0 1 1 1 0 FeoC like transcriptional regulator MarR_2 PF12802.7 ORX92631.1 - 0.091 12.7 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 MarR family Peptidase_S24 PF00717.23 ORX92641.1 - 3.1e-09 36.6 0.0 4.4e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase S24-like DHDPS PF00701.22 ORX92642.1 - 5.6e-37 127.0 0.0 1.1e-36 126.1 0.0 1.4 1 1 0 1 1 1 1 Dihydrodipicolinate synthetase family Pantoate_transf PF02548.15 ORX92642.1 - 0.097 12.0 0.0 8.8 5.6 0.0 2.2 2 0 0 2 2 2 0 Ketopantoate hydroxymethyltransferase SBD_N PF07005.11 ORX92643.1 - 1.8e-62 211.1 0.1 1.2e-61 208.4 0.0 1.9 2 0 0 2 2 2 1 Sugar-binding N-terminal domain NBD_C PF17042.5 ORX92643.1 - 7.1e-41 140.5 0.1 1.5e-40 139.5 0.0 1.5 2 0 0 2 2 2 1 Nucleotide-binding C-terminal domain Transp_cyt_pur PF02133.15 ORX92644.1 - 6.9e-73 245.9 35.9 8.6e-73 245.6 35.9 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Aldo_ket_red PF00248.21 ORX92645.1 - 2.4e-66 223.9 0.0 3e-66 223.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Epimerase PF01370.21 ORX92646.1 - 1.7e-07 31.0 0.0 4.2e-06 26.4 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 ORX92646.1 - 6.2e-05 22.3 0.0 0.085 12.0 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.19 ORX92646.1 - 0.0027 16.8 0.0 0.019 14.0 0.0 1.9 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 ORX92646.1 - 0.0082 15.3 0.0 0.051 12.7 0.0 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 ORX92646.1 - 0.012 15.0 0.0 0.23 10.8 0.0 2.1 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Ldh_1_N PF00056.23 ORX92646.1 - 0.072 13.2 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain His_Phos_1 PF00300.22 ORX92646.1 - 0.18 11.5 0.0 0.28 10.8 0.0 1.3 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) Fungal_trans PF04082.18 ORX92647.1 - 0.00075 18.6 0.4 0.0016 17.5 0.4 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORX92647.1 - 0.056 13.6 0.7 0.093 12.9 0.7 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldo_ket_red PF00248.21 ORX92648.1 - 7.5e-33 114.0 0.0 1.3e-32 113.2 0.0 1.4 1 1 0 1 1 1 1 Aldo/keto reductase family Sugar_tr PF00083.24 ORX92649.1 - 3.9e-75 253.5 23.3 2.1e-71 241.1 16.5 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 ORX92649.1 - 1.2e-15 57.3 31.7 3.4e-15 55.8 27.8 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 ORX92649.1 - 0.00019 21.2 0.9 0.00075 19.2 0.9 2.0 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 MFS_5 PF05631.14 ORX92649.1 - 0.0018 17.3 0.2 0.0018 17.3 0.2 2.0 3 0 0 3 3 3 1 Sugar-tranasporters, 12 TM ATP-synt_J PF04911.12 ORX92649.1 - 0.016 14.7 0.0 0.068 12.8 0.0 2.1 1 0 0 1 1 1 0 ATP synthase j chain BNR_2 PF13088.6 ORX92650.1 - 7.2e-49 166.5 0.4 8.9e-49 166.3 0.4 1.0 1 0 0 1 1 1 1 BNR repeat-like domain Sortilin-Vps10 PF15902.5 ORX92650.1 - 0.0027 16.6 0.0 0.27 10.0 0.0 2.1 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, BNR PF02012.20 ORX92650.1 - 0.0083 16.0 12.4 0.27 11.4 0.1 4.2 4 0 0 4 4 4 2 BNR/Asp-box repeat adh_short PF00106.25 ORX92701.1 - 3.1e-36 124.7 3.6 4.1e-36 124.3 3.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORX92701.1 - 8.9e-26 90.9 4.5 1.8e-25 89.9 4.5 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORX92701.1 - 3.8e-16 59.5 0.8 5.2e-16 59.1 0.8 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ORX92701.1 - 0.0002 20.9 1.5 0.0018 17.8 1.5 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 ORX92701.1 - 0.0043 16.2 0.4 0.0054 15.9 0.4 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.20 ORX92701.1 - 0.056 13.5 0.1 0.12 12.4 0.1 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Ldh_1_N PF00056.23 ORX92701.1 - 0.12 12.5 1.2 0.2 11.7 1.2 1.3 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Fungal_trans PF04082.18 ORX92702.1 - 2.3e-10 39.9 0.0 5.2e-10 38.8 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORX92702.1 - 4.8e-09 36.2 10.8 1.1e-08 35.0 10.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Bac_rhodopsin PF01036.18 ORX92702.1 - 0.026 14.1 0.0 0.052 13.1 0.0 1.4 1 0 0 1 1 1 0 Bacteriorhodopsin-like protein DUF1691 PF07950.11 ORX92703.1 - 3.6e-32 111.3 6.3 1.1e-27 96.8 5.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1691) HemY_N PF07219.13 ORX92703.1 - 0.27 11.4 1.5 2.3 8.5 0.5 2.2 2 0 0 2 2 2 0 HemY protein N-terminus DUF3449 PF11931.8 ORX92704.1 - 0.005 16.7 1.0 0.19 11.5 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3449) zf-C2H2_6 PF13912.6 ORX92704.1 - 0.0084 16.1 0.3 0.017 15.1 0.3 1.5 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2 PF00096.26 ORX92704.1 - 0.0094 16.4 0.5 0.0094 16.4 0.5 2.5 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 ORX92704.1 - 0.046 14.0 2.6 0.075 13.4 1.3 2.0 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 ORX92704.1 - 0.13 13.2 0.3 0.13 13.2 0.3 2.0 2 0 0 2 2 2 0 C2H2-type zinc finger Pkinase PF00069.25 ORX92705.1 - 9.2e-12 44.9 0.2 6.1e-07 29.1 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain TTL PF03133.15 ORX92706.1 - 1.8e-54 184.9 0.0 1e-53 182.4 0.0 1.8 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 ORX92706.1 - 1.1e-05 24.9 0.0 6e-05 22.4 0.0 2.0 2 0 0 2 2 2 1 YheC/D like ATP-grasp Sporozoite_P67 PF05642.11 ORX92706.1 - 0.059 11.5 2.5 0.12 10.4 2.5 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DNA_pol_phi PF04931.13 ORX92706.1 - 0.55 8.3 6.0 0.77 7.8 6.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 ORX92706.1 - 0.81 7.8 3.7 1.2 7.2 3.7 1.2 1 0 0 1 1 1 0 Nop14-like family CENP-B_dimeris PF09026.10 ORX92706.1 - 0.9 10.0 8.8 1.8 9.0 8.8 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain SDA1 PF05285.12 ORX92706.1 - 2.3 7.5 7.3 3.5 7.0 7.3 1.1 1 0 0 1 1 1 0 SDA1 Cytomega_UL84 PF06284.11 ORX92706.1 - 5.4 5.4 7.3 8.2 4.7 7.3 1.2 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein zf-primase PF09329.11 ORX92707.1 - 1.3e-18 66.5 1.5 2.4e-18 65.7 1.5 1.4 1 0 0 1 1 1 1 Primase zinc finger tRNA_anti-codon PF01336.25 ORX92707.1 - 0.09 12.8 0.0 0.24 11.4 0.0 1.7 2 0 0 2 2 2 0 OB-fold nucleic acid binding domain RNase_H2-Ydr279 PF09468.10 ORX92708.1 - 2.1e-39 135.3 0.1 2.1e-39 135.3 0.1 2.3 1 1 1 2 2 2 1 Ydr279p protein family (RNase H2 complex component) wHTH domain Ydr279_N PF17745.1 ORX92708.1 - 3.7e-25 88.0 0.7 9.2e-25 86.7 0.1 2.1 2 0 0 2 2 2 1 Ydr279p protein triple barrel domain TPP_enzyme_N PF02776.18 ORX92709.1 - 7.1e-54 182.0 0.2 3.6e-53 179.7 0.1 2.2 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 ORX92709.1 - 6.7e-49 165.6 0.4 1.1e-47 161.6 0.0 2.7 3 1 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 ORX92709.1 - 1.9e-38 131.3 0.5 3.5e-38 130.4 0.5 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain POR_N PF01855.19 ORX92709.1 - 0.078 12.7 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg DUF953 PF06110.11 ORX92709.1 - 0.18 11.4 0.1 0.53 9.9 0.0 1.7 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF953) TPR_19 PF14559.6 ORX92710.1 - 2.3e-08 34.4 0.0 4e-05 24.1 0.0 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 ORX92710.1 - 1.1e-05 25.2 0.0 5.6 7.3 0.0 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 ORX92710.1 - 2e-05 25.1 0.0 0.016 15.9 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_MalT PF17874.1 ORX92710.1 - 6e-05 22.6 0.1 0.00043 19.8 0.0 2.1 2 0 0 2 2 2 1 MalT-like TPR region TPR_6 PF13174.6 ORX92710.1 - 0.001 19.6 0.1 2.5 8.9 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 ORX92710.1 - 0.0023 18.6 1.0 36 5.5 0.0 4.7 4 1 1 5 5 5 0 Tetratricopeptide repeat Surp PF01805.20 ORX92712.1 - 4.3e-13 49.0 0.0 8.6e-13 48.1 0.0 1.5 1 0 0 1 1 1 1 Surp module RRM_1 PF00076.22 ORX92712.1 - 0.019 14.8 0.0 0.68 9.8 0.0 2.6 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Hydrolase_like PF13242.6 ORX92714.1 - 1.4e-08 34.7 0.0 2.6e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 ORX92714.1 - 3.7e-06 27.4 0.0 1.1e-05 25.8 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 ORX92714.1 - 0.00031 20.9 0.0 0.0017 18.4 0.0 2.1 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Fig1 PF12351.8 ORX92741.1 - 1.3 8.9 12.7 0.062 13.2 7.3 1.5 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 GGACT PF06094.12 ORX92742.1 - 8.3e-12 45.8 0.0 1.1e-11 45.4 0.0 1.1 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like Amidoligase_2 PF12224.8 ORX92743.1 - 1.3e-27 97.0 0.0 1.9e-27 96.5 0.0 1.2 1 0 0 1 1 1 1 Putative amidoligase enzyme PPTA PF01239.22 ORX92745.1 - 3.9e-09 35.9 5.4 0.00012 21.7 0.1 4.1 3 1 0 3 3 3 2 Protein prenyltransferase alpha subunit repeat CHD5 PF04420.14 ORX92746.1 - 1e-32 113.2 7.9 4.1e-29 101.5 7.9 2.5 1 1 0 1 1 1 1 CHD5-like protein HET PF06985.11 ORX92747.1 - 5.6e-22 78.7 0.1 1.2e-21 77.6 0.1 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Kelch_5 PF13854.6 ORX92787.1 - 1.1e-10 41.2 13.2 7.6e-08 32.2 0.1 5.9 6 0 0 6 6 6 2 Kelch motif Kelch_6 PF13964.6 ORX92787.1 - 0.00015 21.9 8.6 1.3 9.4 0.0 5.1 4 1 1 5 5 5 2 Kelch motif Kelch_1 PF01344.25 ORX92787.1 - 0.00076 19.0 1.4 2.7 7.7 0.0 4.6 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.15 ORX92787.1 - 0.0095 15.9 9.2 0.86 9.7 0.0 4.5 6 0 0 6 6 6 2 Kelch motif Kelch_3 PF13415.6 ORX92787.1 - 0.02 15.2 0.9 6.7 7.1 0.1 3.1 2 0 0 2 2 2 0 Galactose oxidase, central domain FeoB_associated PF12669.7 ORX92787.1 - 0.21 12.0 1.2 0.41 11.1 1.2 1.4 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein Glyco_hydro_15 PF00723.21 ORX92788.1 - 3.1e-106 355.9 0.1 3.7e-106 355.6 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.19 ORX92788.1 - 8.9e-33 112.1 0.3 2e-32 110.9 0.3 1.6 1 0 0 1 1 1 1 Starch binding domain MFS_1 PF07690.16 ORX92789.1 - 1.8e-34 119.3 40.1 8.1e-31 107.2 15.9 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORX92789.1 - 1.2e-10 40.9 4.2 1.2e-10 40.9 4.2 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.7 ORX92789.1 - 4.5e-05 22.5 0.0 0.036 12.9 3.2 2.7 2 1 0 2 2 2 2 MFS_1 like family TetR_C_14 PF17754.1 ORX92789.1 - 0.1 12.6 0.2 1.5 8.8 0.0 2.6 3 0 0 3 3 3 0 MftR C-terminal domain MFS_3 PF05977.13 ORX92789.1 - 0.47 8.8 7.8 0.047 12.1 2.1 1.9 2 0 0 2 2 2 0 Transmembrane secretion effector Sigma_reg_N PF13800.6 ORX92790.1 - 0.01 16.1 0.3 0.017 15.4 0.3 1.3 1 0 0 1 1 1 0 Sigma factor regulator N-terminal DUF5305 PF17231.2 ORX92790.1 - 0.021 14.2 0.2 0.028 13.8 0.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5305) EVI2A PF05399.11 ORX92790.1 - 0.022 14.4 0.0 0.029 14.0 0.0 1.1 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) DUF2207 PF09972.9 ORX92790.1 - 0.03 13.1 0.0 0.035 12.9 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) NB PF04159.13 ORX92790.1 - 0.055 13.5 0.5 0.077 13.0 0.5 1.2 1 0 0 1 1 1 0 NB glycoprotein TMIE PF16038.5 ORX92790.1 - 0.055 13.3 0.3 0.1 12.4 0.3 1.4 1 0 0 1 1 1 0 TMIE protein Peptidase_S49_N PF08496.10 ORX92790.1 - 0.077 13.1 0.4 0.12 12.4 0.4 1.3 1 1 0 1 1 1 0 Peptidase family S49 N-terminal DUF2371 PF10177.9 ORX92790.1 - 0.082 13.1 0.0 0.11 12.7 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) Sugar_tr PF00083.24 ORX92796.1 - 2.7e-25 89.1 23.9 3.4e-15 55.8 9.4 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 ORX92796.1 - 2.5e-13 49.7 41.6 3.4e-13 49.3 39.8 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily PEMT PF04191.13 ORX92796.1 - 0.31 11.4 5.3 0.43 11.0 0.3 3.3 3 0 0 3 3 3 0 Phospholipid methyltransferase Aminotran_1_2 PF00155.21 ORX92798.1 - 3.1e-34 118.8 0.0 4.7e-34 118.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 ORX92798.1 - 0.13 10.8 0.0 0.2 10.1 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme RPN7 PF10602.9 ORX92799.1 - 1.2e-53 181.4 0.2 2e-53 180.7 0.2 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 ORX92799.1 - 6.8e-14 52.3 0.0 1.3e-13 51.4 0.0 1.5 1 0 0 1 1 1 1 PCI domain TPR_8 PF13181.6 ORX92799.1 - 0.071 13.4 0.0 0.27 11.6 0.0 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat Pox_MCEL PF03291.16 ORX92800.1 - 6.1e-51 173.5 0.0 9.6e-51 172.9 0.0 1.3 1 1 0 1 1 1 1 mRNA capping enzyme Methyltransf_25 PF13649.6 ORX92800.1 - 5e-10 40.0 0.0 0.00018 22.2 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 ORX92800.1 - 2.4e-09 37.8 0.1 4.1e-08 33.9 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORX92800.1 - 3.4e-06 27.6 0.0 0.13 12.9 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 ORX92800.1 - 4.7e-06 26.5 0.0 1.1e-05 25.4 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORX92800.1 - 4.1e-05 23.4 0.0 0.00091 19.0 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 ORX92800.1 - 0.00065 19.0 0.2 0.0025 17.0 0.0 2.0 2 0 0 2 2 2 1 NNMT/PNMT/TEMT family Methyltransf_9 PF08003.11 ORX92800.1 - 0.03 13.2 0.0 0.041 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_32 PF13679.6 ORX92800.1 - 0.086 12.8 1.3 0.28 11.2 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Arm-DNA-bind_3 PF13356.6 ORX92800.1 - 0.09 13.2 0.1 0.09 13.2 0.1 2.6 3 0 0 3 3 2 0 Arm DNA-binding domain DDRGK PF09756.9 ORX92800.1 - 4.1 6.9 11.3 0.16 11.6 5.5 1.5 2 0 0 2 2 2 0 DDRGK domain GatB_Yqey PF02637.18 ORX92816.1 - 0.23 11.3 1.7 0.85 9.5 1.4 2.0 1 1 1 2 2 2 0 GatB domain DUF3181 PF11378.8 ORX92816.1 - 0.56 10.5 4.2 9.3 6.6 0.3 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF3181) DUF3106 PF11304.8 ORX92816.1 - 2 8.9 14.5 3.9 8.0 10.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3106) MinE PF03776.14 ORX92816.1 - 3.4 7.7 12.8 4.4e+02 1.0 7.6 4.3 1 1 2 3 3 3 0 Septum formation topological specificity factor MinE DUF4209 PF13910.6 ORX92816.1 - 7.9 6.8 8.0 5.7e+02 0.8 8.0 3.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4209) DUF5112 PF17139.4 ORX92816.1 - 8.3 5.8 6.4 14 5.0 1.4 2.3 1 1 2 3 3 3 0 Domain of unknown function (DUF5112) Tim17 PF02466.19 ORX92821.1 - 4.4e-41 139.7 2.5 6.4e-41 139.2 2.5 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF4048 PF13257.6 ORX92822.1 - 2.4e-32 112.8 21.0 2.4e-32 112.8 21.0 3.8 2 1 1 3 3 3 1 Domain of unknown function (DUF4048) YjbT PF17089.5 ORX92822.1 - 0.018 15.1 0.5 0.084 12.9 0.3 2.2 2 0 0 2 2 2 0 Uncharacterised protein family Dicty_REP PF05086.12 ORX92822.1 - 9.9 4.0 7.4 13 3.6 7.4 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Pkinase PF00069.25 ORX92823.1 - 2.7e-69 233.5 0.0 4.4e-69 232.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX92823.1 - 5.8e-49 166.7 0.0 9e-49 166.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORX92823.1 - 6.3e-06 25.2 5.6 0.00011 21.1 0.0 2.8 3 0 0 3 3 3 2 Fungal protein kinase Kinase-like PF14531.6 ORX92823.1 - 0.00061 19.2 0.0 0.0036 16.7 0.0 2.0 2 0 0 2 2 2 1 Kinase-like ABC1 PF03109.16 ORX92823.1 - 0.1 12.7 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 ABC1 family ACT_7 PF13840.6 ORX92824.1 - 4.1e-27 93.7 0.0 4.8e-17 61.5 0.0 2.3 2 0 0 2 2 2 2 ACT domain NUP50 PF08911.11 ORX92824.1 - 0.15 12.7 0.1 0.28 11.9 0.1 1.4 1 0 0 1 1 1 0 NUP50 (Nucleoporin 50 kDa) BetR PF08667.10 ORX92826.1 - 0.15 12.1 0.0 9.3 6.3 0.0 2.1 2 0 0 2 2 2 0 BetR domain Nop10p PF04135.12 ORX92828.1 - 3.1e-19 68.8 0.4 3.7e-19 68.5 0.4 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family TPR_MLP1_2 PF07926.12 ORX92830.1 - 0.0019 18.3 19.0 0.0019 18.3 19.0 7.6 2 2 5 7 7 7 4 TPR/MLP1/MLP2-like protein TolA_bind_tri PF16331.5 ORX92830.1 - 0.007 16.4 6.7 0.007 16.4 6.7 9.0 6 3 2 8 8 8 1 TolA binding protein trimerisation DUF4200 PF13863.6 ORX92830.1 - 0.0095 16.3 5.8 0.0095 16.3 5.8 7.9 1 1 6 7 7 7 1 Domain of unknown function (DUF4200) Rab5-bind PF09311.11 ORX92830.1 - 0.01 15.3 6.4 0.01 15.3 6.4 7.6 3 2 4 8 8 8 0 Rabaptin-like protein Rootletin PF15035.6 ORX92830.1 - 0.01 15.9 12.4 0.01 15.9 12.4 5.6 1 1 4 5 5 5 0 Ciliary rootlet component, centrosome cohesion CENP-F_leu_zip PF10473.9 ORX92830.1 - 0.011 15.8 15.4 0.011 15.8 15.4 7.5 1 1 5 6 6 6 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PRKG1_interact PF15898.5 ORX92830.1 - 0.022 15.7 17.1 0.022 15.7 17.1 8.2 3 2 4 7 7 7 0 cGMP-dependent protein kinase interacting domain Shugoshin_N PF07558.11 ORX92830.1 - 0.3 11.0 17.0 2 8.4 3.1 5.0 4 0 0 4 4 4 0 Shugoshin N-terminal coiled-coil region Abhydrolase_2 PF02230.16 ORX92832.1 - 0.00024 21.0 0.0 0.00037 20.4 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Esterase PF00756.20 ORX92832.1 - 0.09 12.4 0.1 5.6 6.5 0.0 2.3 2 0 0 2 2 2 0 Putative esterase Esterase_phd PF10503.9 ORX92832.1 - 0.1 12.1 2.3 0.58 9.6 0.1 2.7 2 1 1 3 3 3 0 Esterase PHB depolymerase MFS_1 PF07690.16 ORX92833.1 - 1.5e-10 40.5 12.2 2e-10 40.2 12.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORX92833.1 - 2e-05 23.6 0.9 2.2e-05 23.5 0.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter DUF1040 PF06288.13 ORX92858.1 - 0.045 14.1 0.1 0.09 13.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1040) Casein PF00363.18 ORX92858.1 - 0.067 13.6 1.3 6.5 7.2 0.3 2.2 2 0 0 2 2 2 0 Casein DUF4778 PF16008.5 ORX92858.1 - 0.12 12.4 4.3 0.16 12.0 4.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) CwsA PF10814.8 ORX92858.1 - 0.29 11.3 7.5 0.28 11.4 0.2 2.1 2 0 0 2 2 2 0 Cell wall synthesis protein CwsA DUF3435 PF11917.8 ORX92877.1 - 8.4e-12 44.7 3.8 8.8e-12 44.7 3.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) zf-H2C2_2 PF13465.6 ORX92894.1 - 3.8e-13 49.2 9.3 5.7e-08 32.8 0.2 3.6 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.26 ORX92894.1 - 8.6e-13 48.0 12.7 2.8e-06 27.5 2.4 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORX92894.1 - 4.7e-09 36.3 10.6 0.00031 21.3 1.5 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 ORX92894.1 - 1.4e-08 34.5 5.8 0.00025 21.0 0.3 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORX92894.1 - 3.5e-06 27.1 0.4 0.068 13.5 0.1 3.4 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ORX92894.1 - 1.7e-05 25.0 0.9 0.01 16.2 0.2 3.1 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-Di19 PF05605.12 ORX92894.1 - 0.034 14.4 1.4 0.066 13.5 1.4 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Zn_ribbon_recom PF13408.6 ORX92894.1 - 0.095 13.2 0.7 0.23 12.0 0.7 1.6 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain LIM PF00412.22 ORX92894.1 - 0.22 11.8 3.0 9.5 6.5 0.2 2.4 1 1 1 2 2 2 0 LIM domain C5HCH PF17982.1 ORX92894.1 - 3 8.1 6.3 12 6.1 1.4 2.7 1 1 1 2 2 2 0 NSD Cys-His rich domain zf-C2H2_11 PF16622.5 ORX92894.1 - 3 7.7 13.6 0.32 10.8 0.7 3.4 4 0 0 4 4 3 0 zinc-finger C2H2-type BRO1 PF03097.18 ORX92895.1 - 2e-125 418.6 0.3 5e-124 414.1 0.0 2.4 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 ORX92895.1 - 1.6e-85 287.0 8.6 1.6e-85 287.0 8.6 2.0 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV SpoU_sub_bind PF08032.12 ORX92895.1 - 0.063 13.6 3.9 10 6.5 0.0 4.3 5 0 0 5 5 5 0 RNA 2'-O ribose methyltransferase substrate binding Cytadhesin_P30 PF07271.11 ORX92895.1 - 0.064 12.8 0.4 0.1 12.1 0.4 1.3 1 0 0 1 1 1 0 Cytadhesin P30/P32 HMA PF00403.26 ORX92896.1 - 8.9e-17 61.3 1.2 1e-16 61.1 1.2 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain DUF211 PF02680.14 ORX92896.1 - 0.013 15.6 0.1 0.017 15.3 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized ArCR, COG1888 Fer2_BFD PF04324.15 ORX92896.1 - 0.1 13.0 0.3 0.21 11.9 0.1 1.7 2 0 0 2 2 2 0 BFD-like [2Fe-2S] binding domain DJ-1_PfpI PF01965.24 ORX92897.1 - 1.4e-08 34.8 0.0 1.8e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family EHN PF06441.12 ORX92897.1 - 0.14 12.5 0.7 0.67 10.4 0.7 2.0 2 1 0 2 2 2 0 Epoxide hydrolase N terminus PRELI PF04707.14 ORX92898.1 - 2e-44 151.1 0.1 2.5e-44 150.8 0.1 1.1 1 0 0 1 1 1 1 PRELI-like family adh_short_C2 PF13561.6 ORX92899.1 - 4.1e-37 128.0 3.3 3.8e-33 115.0 1.4 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORX92899.1 - 8.6e-36 123.2 2.8 1.4e-35 122.5 1.8 1.7 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 ORX92899.1 - 1.8e-14 54.1 1.8 1.2e-13 51.3 1.2 1.9 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 ORX92899.1 - 0.077 12.4 0.4 0.75 9.2 0.4 2.3 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Acyl_transf_1 PF00698.21 ORX92900.1 - 6.2e-14 52.2 0.0 5.3e-08 32.7 0.0 2.1 1 1 0 2 2 2 2 Acyl transferase domain DUF2458 PF10454.9 ORX92900.1 - 0.067 12.8 0.0 0.16 11.6 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2458) Med5 PF08689.10 ORX92901.1 - 7.5e-150 500.9 0.0 4e-149 498.5 0.0 2.1 1 1 0 1 1 1 1 Mediator complex subunit Med5 Asp_protease_2 PF13650.6 ORX92925.1 - 3.1e-11 43.7 0.0 0.00011 22.8 0.0 2.4 2 0 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 ORX92925.1 - 1.2e-07 32.1 0.0 0.024 15.2 0.0 2.4 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 ORX92925.1 - 0.017 14.9 0.0 0.034 13.9 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease DUF5313 PF17240.2 ORX92926.1 - 0.14 12.6 0.5 0.28 11.6 0.5 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5313) DUF983 PF06170.12 ORX92926.1 - 2.3 8.7 4.6 3.1 8.3 4.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF983) PNP_UDP_1 PF01048.20 ORX92928.1 - 2.1e-40 138.5 0.0 2.6e-40 138.2 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily Amidase PF01425.21 ORX92929.1 - 3.4e-74 250.5 0.1 7.6e-74 249.3 0.1 1.5 1 1 0 1 1 1 1 Amidase HET PF06985.11 ORX92930.1 - 1e-27 97.3 0.0 1.2e-27 97.0 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HET PF06985.11 ORX92931.1 - 0.026 14.9 0.4 0.037 14.4 0.4 1.2 1 0 0 1 1 1 0 Heterokaryon incompatibility protein (HET) HNH PF01844.23 ORX92932.1 - 0.0035 17.5 0.1 4 7.7 0.0 2.4 2 0 0 2 2 2 2 HNH endonuclease HNH_5 PF14279.6 ORX92932.1 - 0.032 14.1 0.6 9.1 6.2 0.0 2.3 2 0 0 2 2 2 0 HNH endonuclease Abhydrolase_6 PF12697.7 ORX92933.1 - 6.4e-14 53.1 0.0 7.4e-14 52.9 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Pyr_redox_2 PF07992.14 ORX92934.1 - 1.6e-19 70.2 0.1 5.7e-17 61.9 0.1 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORX92934.1 - 0.00054 20.5 1.6 0.0013 19.3 0.6 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ORX92934.1 - 0.0026 17.8 0.1 0.079 13.0 0.0 3.0 4 0 0 4 4 4 1 FAD-NAD(P)-binding Trp_halogenase PF04820.14 ORX92934.1 - 0.033 13.1 1.2 1.3 7.8 0.0 2.2 2 0 0 2 2 2 0 Tryptophan halogenase CDH-cyt PF16010.5 ORX92935.1 - 8.2e-57 191.8 0.1 1.8e-56 190.7 0.1 1.6 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase GMC_oxred_N PF00732.19 ORX92935.1 - 2.7e-29 102.5 0.0 5.2e-29 101.6 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 ORX92935.1 - 1.5e-20 74.2 0.3 1.5e-20 74.2 0.3 1.8 2 0 0 2 2 2 1 GMC oxidoreductase DAO PF01266.24 ORX92935.1 - 1.3e-05 24.9 1.2 0.0083 15.7 0.2 2.7 3 0 0 3 3 3 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 ORX92935.1 - 3.2e-05 23.2 1.3 0.015 14.4 1.1 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 ORX92935.1 - 0.0056 15.9 0.2 0.39 9.9 0.2 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ORX92935.1 - 0.0059 15.4 1.2 0.021 13.6 0.7 1.9 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 ORX92935.1 - 0.0081 15.5 1.4 0.18 11.1 0.3 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ORX92935.1 - 0.028 14.6 0.3 0.11 12.7 0.3 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 ORX92935.1 - 0.041 12.9 0.1 0.077 12.0 0.1 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein ApbA PF02558.16 ORX92935.1 - 0.11 12.1 0.2 0.27 10.9 0.2 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DOMON PF03351.17 ORX92935.1 - 0.12 12.5 0.2 0.41 10.9 0.0 1.9 2 0 0 2 2 2 0 DOMON domain Pyr_redox PF00070.27 ORX92935.1 - 0.3 11.7 1.9 37 5.0 0.4 3.2 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Glyco_hydro_114 PF03537.13 ORX92936.1 - 1.1e-58 198.3 0.5 1.2e-58 198.2 0.5 1.0 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 GTP_EFTU PF00009.27 ORX92959.1 - 1.7e-48 164.7 0.6 1.7e-48 164.7 0.6 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.10 ORX92959.1 - 3.3e-24 85.0 3.0 3.3e-24 85.0 3.0 1.8 2 0 0 2 2 2 1 HBS1 N-terminus GTP_EFTU_D3 PF03143.17 ORX92959.1 - 6e-08 33.0 0.0 1.6e-07 31.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 ORX92959.1 - 1.2e-07 31.8 0.0 0.00033 20.7 0.0 2.7 1 1 1 2 2 2 2 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 ORX92959.1 - 9e-06 26.0 0.6 7.6e-05 23.0 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu domain 2 Ras PF00071.22 ORX92959.1 - 0.00057 19.5 0.5 0.0046 16.6 0.1 2.1 2 0 0 2 2 2 1 Ras family Roc PF08477.13 ORX92959.1 - 0.0007 19.8 0.1 0.082 13.1 0.0 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 ORX92959.1 - 0.0018 17.7 0.0 0.21 11.0 0.0 2.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 ORX92959.1 - 0.032 13.6 0.1 0.057 12.8 0.1 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 ORX92959.1 - 0.061 12.9 0.1 1.3 8.5 0.1 2.9 2 1 0 2 2 2 0 Ferrous iron transport protein B PTPA PF03095.15 ORX92961.1 - 3.5e-119 397.7 0.0 4.1e-119 397.5 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein MMU163 PF17119.5 ORX92961.1 - 0.13 11.4 0.0 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis PAN_4 PF14295.6 ORX92962.1 - 0.14 12.0 3.8 0.32 10.9 3.8 1.5 1 0 0 1 1 1 0 PAN domain TPR_8 PF13181.6 ORX92966.1 - 0.0052 16.9 0.2 0.087 13.1 0.0 3.0 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 ORX92966.1 - 0.0076 16.3 0.1 0.17 12.1 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 ORX92966.1 - 0.027 15.1 0.3 0.16 12.7 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 ORX92966.1 - 0.029 14.2 0.1 0.21 11.5 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Hid1 PF12722.7 ORX92967.1 - 0.83 7.7 3.3 1 7.4 3.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SAPS PF04499.15 ORX92967.1 - 0.95 8.2 7.8 1.1 8.0 7.8 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Pkinase PF00069.25 ORX92980.1 - 7.5e-72 241.9 0.0 1.1e-71 241.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX92980.1 - 4.4e-34 117.9 0.0 7.2e-34 117.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 ORX92980.1 - 0.0016 17.8 0.0 0.0039 16.6 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 ORX92980.1 - 0.0031 16.5 0.1 0.013 14.5 0.0 1.8 2 0 0 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 ORX92980.1 - 0.0052 16.2 0.0 0.0086 15.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 ORX92980.1 - 0.18 10.5 0.0 0.18 10.5 0.0 2.0 3 0 0 3 3 3 0 Fungal protein kinase AMP-binding PF00501.28 ORX92983.1 - 3.2e-44 151.2 0.0 4.2e-44 150.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 ORX92983.1 - 2.7e-06 27.2 1.6 4.4e-06 26.5 0.4 2.0 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus Peptidase_M54 PF07998.11 ORX92983.1 - 0.086 12.8 0.1 0.15 12.0 0.1 1.3 1 0 0 1 1 1 0 Peptidase family M54 CAF1C_H4-bd PF12265.8 ORX92984.1 - 4.6e-24 84.5 0.5 1.5e-23 82.8 0.2 2.1 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 ORX92984.1 - 3.7e-20 71.9 3.4 0.004 18.0 0.1 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat GDPD_2 PF13653.6 ORX92986.1 - 0.015 15.8 0.7 0.032 14.7 0.7 1.6 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family DUF4996 PF16387.5 ORX92986.1 - 0.14 12.6 0.0 0.94 10.0 0.0 2.3 2 1 1 3 3 3 0 Domain of unknown function Peptidase_C78 PF07910.13 ORX93012.1 - 2.6e-63 213.3 0.0 3.5e-63 212.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C78 zf-RAG1 PF10426.9 ORX93012.1 - 0.0042 17.2 0.1 0.011 15.9 0.1 1.7 1 0 0 1 1 1 1 Recombination-activating protein 1 zinc-finger domain Herpes_UL36 PF03586.13 ORX93012.1 - 0.039 13.3 0.0 0.1 11.9 0.0 1.6 2 0 0 2 2 2 0 Herpesvirus UL36 tegument protein EcsB PF05975.12 ORX93013.1 - 0.014 14.3 0.1 0.016 14.1 0.1 1.0 1 0 0 1 1 1 0 Bacterial ABC transporter protein EcsB Torus PF16131.5 ORX93014.1 - 3.4e-41 140.3 0.1 3.4e-41 140.3 0.1 2.4 3 0 0 3 3 3 1 Torus domain RRM_1 PF00076.22 ORX93014.1 - 1.2e-05 25.1 0.0 2e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 ORX93014.1 - 0.00084 19.3 0.2 0.0022 18.0 0.2 1.7 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 ORX93014.1 - 0.0074 16.2 0.3 0.013 15.4 0.3 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Nup35_RRM_2 PF14605.6 ORX93014.1 - 0.11 12.5 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif CMAS PF02353.20 ORX93015.1 - 2.1e-36 125.6 0.4 2.8e-36 125.2 0.4 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.12 ORX93015.1 - 6.4e-15 55.6 0.0 1.1e-14 54.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORX93015.1 - 2.5e-14 53.8 0.0 4e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORX93015.1 - 2.5e-13 50.1 0.0 3.5e-13 49.6 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORX93015.1 - 3.1e-09 36.9 0.0 4.5e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORX93015.1 - 8.4e-09 36.1 0.0 1.4e-08 35.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ORX93015.1 - 1.5e-06 27.8 0.0 2.8e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain DUF938 PF06080.12 ORX93015.1 - 0.00021 21.1 0.0 0.00034 20.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF938) PCMT PF01135.19 ORX93015.1 - 0.0004 20.2 0.0 0.002 17.9 0.0 2.0 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.18 ORX93015.1 - 0.0007 19.0 0.0 0.001 18.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltr_RsmB-F PF01189.17 ORX93015.1 - 0.00082 19.1 0.0 0.0014 18.3 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltransf_4 PF02390.17 ORX93015.1 - 0.0011 18.5 0.0 0.0024 17.4 0.0 1.5 2 0 0 2 2 2 1 Putative methyltransferase TehB PF03848.14 ORX93015.1 - 0.0037 16.7 0.0 0.0056 16.1 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_2 PF00891.18 ORX93015.1 - 0.0044 16.3 0.0 0.0069 15.7 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain GidB PF02527.15 ORX93015.1 - 0.028 13.7 0.0 0.047 13.0 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G MetW PF07021.12 ORX93015.1 - 0.12 11.9 0.0 0.26 10.9 0.0 1.5 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW NADH_B2 PF14813.6 ORX93016.1 - 0.0086 15.8 0.1 0.0092 15.8 0.1 1.1 1 0 0 1 1 1 1 NADH dehydrogenase 1 beta subcomplex subunit 2 Pkinase PF00069.25 ORX93017.1 - 1.1e-64 218.4 0.0 1.3e-64 218.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX93017.1 - 2.8e-28 98.9 0.0 3.8e-28 98.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORX93017.1 - 0.0015 17.9 0.1 0.029 13.7 0.0 2.2 2 1 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 ORX93017.1 - 0.0065 15.3 0.0 0.01 14.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 ORX93017.1 - 0.0093 15.3 0.1 0.019 14.3 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 ORX93017.1 - 0.038 12.9 0.1 0.11 11.4 0.1 1.6 1 1 0 1 1 1 0 Haspin like kinase domain AA_kinase PF00696.28 ORX93018.1 - 2.2e-42 145.3 0.1 3.7e-42 144.6 0.1 1.4 1 0 0 1 1 1 1 Amino acid kinase family ACT_7 PF13840.6 ORX93018.1 - 2e-09 37.1 0.8 1.9e-07 30.8 0.1 2.6 2 0 0 2 2 2 2 ACT domain ACT PF01842.25 ORX93018.1 - 4e-09 36.1 0.3 3.3e-07 30.0 0.1 2.8 2 0 0 2 2 2 1 ACT domain Pinin_SDK_N PF04697.13 ORX93021.1 - 0.061 14.0 7.3 0.058 14.0 6.4 1.5 1 1 0 1 1 1 0 pinin/SDK conserved region AT_hook PF02178.19 ORX93021.1 - 0.62 10.1 0.2 0.62 10.1 0.2 2.8 2 0 0 2 2 2 0 AT hook motif TT_ORF2 PF02957.15 ORX93021.1 - 3.4 8.6 10.9 7.6 7.5 2.0 2.2 1 1 1 2 2 2 0 TT viral ORF2 AAA PF00004.29 ORX93023.1 - 1.8e-16 60.7 0.0 3.1e-16 60.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.11 ORX93023.1 - 5.6e-14 52.3 0.0 1.7e-13 50.7 0.0 1.8 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 ORX93023.1 - 2.1e-12 47.1 0.0 6.7e-12 45.5 0.0 1.8 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.15 ORX93023.1 - 4.2e-10 39.9 0.0 7.3e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_assoc_2 PF16193.5 ORX93023.1 - 1.6e-06 28.4 0.0 5.9e-06 26.5 0.0 2.1 1 1 0 1 1 1 1 AAA C-terminal domain AAA_16 PF13191.6 ORX93023.1 - 1.9e-06 28.3 0.0 7.2e-06 26.5 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 ORX93023.1 - 2.2e-06 27.6 0.0 3.9e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain DNA_pol3_delta PF06144.13 ORX93023.1 - 2.9e-06 27.2 0.1 5.3e-06 26.3 0.1 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_11 PF13086.6 ORX93023.1 - 3.2e-06 27.1 0.2 0.00011 22.1 0.0 2.1 1 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 ORX93023.1 - 4.8e-06 26.6 0.1 1.4e-05 25.1 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 ORX93023.1 - 1.2e-05 25.1 0.0 2.2e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 ORX93023.1 - 1.5e-05 25.3 0.1 0.00012 22.3 0.1 2.3 2 1 0 2 2 1 1 AAA domain RuvB_N PF05496.12 ORX93023.1 - 3.4e-05 23.6 0.0 0.00013 21.7 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain DUF815 PF05673.13 ORX93023.1 - 7.7e-05 22.0 0.0 0.00013 21.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_3 PF07726.11 ORX93023.1 - 0.00013 21.8 0.1 0.00062 19.6 0.1 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ResIII PF04851.15 ORX93023.1 - 0.00055 20.0 0.0 0.045 13.8 0.0 2.2 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit Mg_chelatase PF01078.21 ORX93023.1 - 0.00068 19.1 0.1 0.016 14.6 0.1 2.6 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 ORX93023.1 - 0.00079 19.8 0.1 0.0029 17.9 0.1 1.8 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 ORX93023.1 - 0.00081 18.9 0.0 0.21 11.0 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein AAA_14 PF13173.6 ORX93023.1 - 0.0013 18.7 0.0 0.0032 17.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 ORX93023.1 - 0.0053 16.5 0.0 0.01 15.5 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain TniB PF05621.11 ORX93023.1 - 0.0056 16.1 0.0 0.062 12.7 0.0 2.2 2 0 0 2 2 2 1 Bacterial TniB protein DUF2075 PF09848.9 ORX93023.1 - 0.0083 15.4 0.0 0.013 14.8 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) NACHT PF05729.12 ORX93023.1 - 0.0097 15.8 0.0 0.02 14.8 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_18 PF13238.6 ORX93023.1 - 0.013 16.0 0.0 0.024 15.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain DEAD PF00270.29 ORX93023.1 - 0.018 14.8 0.1 0.12 12.1 0.1 2.1 1 1 1 2 2 2 0 DEAD/DEAH box helicase AAA_28 PF13521.6 ORX93023.1 - 0.02 15.1 0.0 0.036 14.3 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 ORX93023.1 - 0.027 14.0 0.0 0.072 12.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 ORX93023.1 - 0.028 14.0 0.0 0.06 12.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 ORX93023.1 - 0.047 14.1 0.0 0.17 12.3 0.0 1.8 1 1 0 1 1 1 0 RNA helicase IstB_IS21 PF01695.17 ORX93023.1 - 0.083 12.6 0.0 0.7 9.6 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein ATPase_2 PF01637.18 ORX93023.1 - 0.09 12.7 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea TK PF00265.18 ORX93023.1 - 0.1 12.5 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Thymidine kinase DUF1002 PF06207.11 ORX93023.1 - 0.11 12.0 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1002) PIF1 PF05970.14 ORX93023.1 - 0.12 11.5 0.0 0.34 10.0 0.0 1.6 1 1 0 1 1 1 0 PIF1-like helicase P21-Arc PF04062.14 ORX93024.1 - 1.7e-72 243.1 0.0 2.2e-72 242.8 0.0 1.1 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit DUF1082 PF06449.11 ORX93069.1 - 0.07 13.0 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial domain of unknown function (DUF1082) Pkinase PF00069.25 ORX93070.1 - 0.00017 21.1 0.0 0.00018 21.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain STPPase_N PF16891.5 ORX93121.1 - 0.093 13.2 0.1 15 6.1 0.0 2.4 2 0 0 2 2 2 0 Serine-threonine protein phosphatase N-terminal domain adh_short PF00106.25 ORX93123.1 - 0.033 13.6 0.0 0.042 13.3 0.0 1.0 1 0 0 1 1 1 0 short chain dehydrogenase DUF1664 PF07889.12 ORX93124.1 - 0.0048 16.9 0.3 0.014 15.5 0.3 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) DUF948 PF06103.11 ORX93124.1 - 4.8 7.5 4.7 3.9 7.8 0.7 2.5 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) TcA_TcB_BD PF18276.1 ORX93125.1 - 7.2e-96 320.6 1.5 5.5e-94 314.5 1.5 2.1 1 1 0 1 1 1 1 Tc toxin complex TcA C-terminal TcB-binding domain DUF2721 PF11026.8 ORX93125.1 - 0.19 11.6 2.1 0.46 10.4 2.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) FMO-like PF00743.19 ORX93126.1 - 1.1e-12 47.2 0.0 1.8e-11 43.2 0.0 2.1 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 ORX93126.1 - 1.2e-08 34.5 0.0 2.4e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ORX93126.1 - 5.9e-08 32.2 0.0 1.7e-05 24.2 0.0 2.2 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 ORX93126.1 - 6.4e-08 32.2 0.0 7.6e-07 28.6 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ORX93126.1 - 0.00035 20.6 0.1 0.0018 18.3 0.0 2.3 2 1 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 ORX93126.1 - 0.0019 18.4 0.0 0.0045 17.2 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ORX93126.1 - 0.0049 16.5 0.2 0.83 9.2 0.5 2.3 1 1 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.17 ORX93126.1 - 0.032 13.5 0.0 0.08 12.2 0.0 1.6 1 0 0 1 1 1 0 Thi4 family FMO-like PF00743.19 ORX93127.1 - 3.5e-39 134.7 0.1 5.2e-23 81.3 0.1 3.0 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 ORX93127.1 - 9.2e-15 54.7 0.2 3.7e-08 33.0 0.2 3.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ORX93127.1 - 7.8e-11 41.7 0.0 5.3e-10 39.0 0.0 2.2 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ORX93127.1 - 3.7e-07 29.6 1.0 0.00016 20.9 0.0 3.0 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 ORX93127.1 - 5.8e-07 29.0 0.0 3.6e-05 23.1 0.0 2.1 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.6 ORX93127.1 - 5.8e-06 26.4 0.0 0.0004 20.4 0.0 2.8 3 0 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 ORX93127.1 - 6.3e-06 26.3 0.0 1.5e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ORX93127.1 - 0.00061 19.5 0.0 0.14 11.7 0.0 3.0 3 0 0 3 3 3 1 FAD dependent oxidoreductase HI0933_like PF03486.14 ORX93127.1 - 0.0025 16.6 0.1 0.077 11.7 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 ORX93127.1 - 0.058 14.0 0.0 1.1 9.9 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase CoA_binding PF02629.19 ORX93127.1 - 0.15 12.7 0.0 6.8 7.5 0.0 3.0 3 0 0 3 3 3 0 CoA binding domain Phosphonate-bd PF12974.7 ORX93128.1 - 7.7e-06 25.7 0.0 1.1e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein SBP_bac_3 PF00497.20 ORX93128.1 - 2.1e-05 24.0 0.0 3.8e-05 23.2 0.0 1.5 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 NMT1 PF09084.11 ORX93128.1 - 3e-05 24.1 0.0 0.0001 22.3 0.0 1.7 1 1 0 1 1 1 1 NMT1/THI5 like NAPRTase_N PF17767.1 ORX93128.1 - 0.033 14.6 0.0 0.057 13.8 0.0 1.3 1 0 0 1 1 1 0 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain NMT1_3 PF16868.5 ORX93128.1 - 0.1 12.0 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 NMT1-like family SRP54 PF00448.22 ORX93129.1 - 5.1e-76 254.7 1.1 1.4e-75 253.3 0.5 1.9 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 ORX93129.1 - 5.8e-32 110.3 4.7 5.8e-32 110.3 4.7 3.7 2 1 2 4 4 3 1 Signal peptide binding domain SRP54_N PF02881.19 ORX93129.1 - 1.6e-20 73.1 0.6 3.6e-20 71.9 0.6 1.7 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain AAA_33 PF13671.6 ORX93129.1 - 3.9e-07 30.3 0.1 1.9e-06 28.1 0.0 2.2 2 1 0 2 2 2 1 AAA domain cobW PF02492.19 ORX93129.1 - 6.3e-06 25.9 1.2 3.5e-05 23.5 1.2 2.1 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.6 ORX93129.1 - 0.0001 22.7 0.1 0.0004 20.8 0.1 2.1 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ORX93129.1 - 0.00044 20.7 0.0 0.00081 19.8 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 ORX93129.1 - 0.0017 18.6 0.1 0.005 17.1 0.1 1.9 1 1 0 1 1 1 1 AAA domain CbiA PF01656.23 ORX93129.1 - 0.0026 17.8 0.0 0.0059 16.6 0.0 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_18 PF13238.6 ORX93129.1 - 0.0043 17.6 0.0 0.0099 16.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain SRPRB PF09439.10 ORX93129.1 - 0.0043 16.5 1.0 1.4 8.3 0.1 3.2 2 1 0 3 3 3 1 Signal recognition particle receptor beta subunit AAA_30 PF13604.6 ORX93129.1 - 0.0044 16.8 0.8 0.0096 15.7 0.0 2.0 2 1 0 2 2 2 1 AAA domain APS_kinase PF01583.20 ORX93129.1 - 0.0048 16.8 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 Adenylylsulphate kinase Thymidylate_kin PF02223.17 ORX93129.1 - 0.0049 16.6 0.1 0.036 13.7 0.0 2.3 2 0 0 2 2 2 1 Thymidylate kinase DUF3052 PF11253.8 ORX93129.1 - 0.0066 16.4 0.1 0.023 14.6 0.1 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3052) MobB PF03205.14 ORX93129.1 - 0.0071 16.2 0.0 0.024 14.5 0.0 1.9 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.12 ORX93129.1 - 0.0095 15.2 0.0 0.019 14.2 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin MMR_HSR1 PF01926.23 ORX93129.1 - 0.013 15.5 0.1 0.087 12.9 0.1 2.3 2 1 0 2 2 2 0 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 ORX93129.1 - 0.014 15.2 0.5 0.061 13.1 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_19 PF13245.6 ORX93129.1 - 0.016 15.5 0.0 0.041 14.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 ORX93129.1 - 0.018 15.5 0.0 0.053 14.0 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ResIII PF04851.15 ORX93129.1 - 0.032 14.3 0.3 0.21 11.6 0.3 2.1 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_28 PF13521.6 ORX93129.1 - 0.052 13.8 0.0 0.093 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain 6PF2K PF01591.18 ORX93129.1 - 0.055 12.8 0.0 0.096 12.0 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase TrwB_AAD_bind PF10412.9 ORX93129.1 - 0.056 12.3 0.0 0.11 11.3 0.0 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_31 PF13614.6 ORX93129.1 - 0.062 13.2 0.0 0.16 11.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain ArsA_ATPase PF02374.15 ORX93129.1 - 4.1 6.5 6.1 1.1 8.3 0.1 2.8 2 2 0 3 3 3 0 Anion-transporting ATPase Rrp15p PF07890.12 ORX93130.1 - 7.9e-37 126.6 12.6 7.9e-37 126.6 12.6 2.5 2 1 0 2 2 2 1 Rrp15p Fer2 PF00111.27 ORX93131.1 - 4.8e-14 52.1 0.5 6.5e-14 51.7 0.5 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Mito_carr PF00153.27 ORX93132.1 - 3.6e-11 42.8 0.1 0.0019 18.0 0.0 3.9 3 1 0 3 3 3 2 Mitochondrial carrier protein XhlA PF10779.9 ORX93176.1 - 0.00076 19.6 2.1 0.001 19.2 2.1 1.3 1 0 0 1 1 1 1 Haemolysin XhlA DASH_Spc19 PF08287.11 ORX93176.1 - 0.0037 17.2 1.4 0.0056 16.6 1.4 1.2 1 0 0 1 1 1 1 Spc19 DUF724 PF05266.14 ORX93176.1 - 0.0072 16.2 0.8 0.0091 15.8 0.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF724) LXG PF04740.12 ORX93176.1 - 0.018 14.8 0.0 0.02 14.6 0.0 1.1 1 0 0 1 1 1 0 LXG domain of WXG superfamily Laminin_I PF06008.14 ORX93176.1 - 0.027 14.2 2.6 0.036 13.8 2.6 1.1 1 0 0 1 1 1 0 Laminin Domain I Spc24 PF08286.11 ORX93176.1 - 0.027 14.7 1.7 0.038 14.2 1.7 1.2 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 SYCE1 PF15233.6 ORX93176.1 - 0.03 14.4 3.4 0.041 14.0 3.4 1.1 1 0 0 1 1 1 0 Synaptonemal complex central element protein 1 DUF16 PF01519.16 ORX93176.1 - 0.068 13.7 0.6 0.09 13.3 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF16 FlaC_arch PF05377.11 ORX93176.1 - 0.081 13.3 1.7 0.14 12.6 1.7 1.3 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) RAMP4 PF06624.12 ORX93176.1 - 0.17 12.0 0.1 0.51 10.4 0.0 1.7 1 1 1 2 2 2 0 Ribosome associated membrane protein RAMP4 Apq12 PF12716.7 ORX93178.1 - 2.8e-18 65.6 9.2 2.8e-18 65.6 9.2 1.5 2 0 0 2 2 2 1 Nuclear pore assembly and biogenesis Polyoma_lg_T_C PF06431.11 ORX93178.1 - 0.021 13.7 0.1 0.022 13.7 0.1 1.2 1 0 0 1 1 1 0 Polyomavirus large T antigen C-terminus RNB PF00773.19 ORX93181.1 - 4.2e-99 332.0 0.3 6.6e-99 331.3 0.3 1.3 1 0 0 1 1 1 1 RNB domain Rrp44_CSD1 PF17216.3 ORX93181.1 - 2.7e-32 111.5 0.5 1.2e-31 109.5 0.0 2.3 2 0 0 2 2 2 1 Rrp44-like cold shock domain Rrp44_S1 PF17215.3 ORX93181.1 - 3.5e-31 107.0 0.8 8.4e-31 105.8 0.8 1.7 1 0 0 1 1 1 1 S1 domain OB_Dis3 PF17849.1 ORX93181.1 - 6.8e-20 70.9 0.0 1.9e-19 69.5 0.0 1.8 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) CSD2 PF17876.1 ORX93181.1 - 1.4e-08 34.8 0.0 0.00031 20.8 0.0 3.3 3 0 0 3 3 3 2 Cold shock domain PIN_4 PF13638.6 ORX93181.1 - 2e-08 34.6 0.2 1.6e-07 31.7 0.1 2.5 2 0 0 2 2 2 1 PIN domain Dis3l2_C_term PF17877.1 ORX93181.1 - 0.00044 20.5 0.3 0.0017 18.7 0.0 2.2 2 0 0 2 2 2 1 DIS3-like exonuclease 2 C terminal V-ATPase_H_N PF03224.14 ORX93182.1 - 3.1e-75 253.4 0.0 4.1e-75 253.0 0.0 1.2 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 ORX93182.1 - 3.7e-37 127.0 0.1 2.5e-36 124.3 0.0 2.4 3 0 0 3 3 3 1 V-ATPase subunit H FUSC PF04632.12 ORX93182.1 - 0.11 11.1 1.7 0.19 10.3 1.7 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Epimerase PF01370.21 ORX93183.1 - 2.6e-18 66.4 0.0 3.2e-18 66.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ORX93183.1 - 2.8e-10 40.1 0.3 0.00032 20.2 0.0 2.5 2 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase NmrA PF05368.13 ORX93183.1 - 7e-09 35.6 0.0 1.5e-07 31.2 0.0 2.0 2 0 0 2 2 2 1 NmrA-like family RmlD_sub_bind PF04321.17 ORX93183.1 - 1.2e-06 27.9 0.0 2.3e-06 26.9 0.0 1.4 1 1 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 ORX93183.1 - 1.3e-06 27.7 0.0 4.5e-06 25.9 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 ORX93183.1 - 5.3e-06 26.5 0.0 8.1e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 ORX93183.1 - 0.00061 19.0 0.4 0.03 13.4 0.0 2.1 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein CRC_subunit PF08624.10 ORX93184.1 - 4.5e-53 179.3 0.0 6.6e-53 178.8 0.0 1.2 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit TPR_2 PF07719.17 ORX93200.1 - 2.1e-07 30.5 1.8 0.037 14.1 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat F-box PF00646.33 ORX93200.1 - 4.8e-07 29.5 0.4 3.7e-06 26.7 0.1 2.5 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 ORX93200.1 - 7.9e-06 25.7 0.8 0.00023 21.0 0.1 3.2 2 1 1 3 3 3 1 F-box-like LRR_8 PF13855.6 ORX93200.1 - 0.00055 19.6 2.6 0.0093 15.7 0.1 3.9 5 0 0 5 5 5 1 Leucine rich repeat LRR_4 PF12799.7 ORX93200.1 - 0.0032 17.9 14.8 0.26 11.8 0.0 6.2 3 1 5 8 8 8 2 Leucine Rich repeats (2 copies) TPR_1 PF00515.28 ORX93200.1 - 0.043 13.6 2.2 33 4.5 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat LRR_1 PF00560.33 ORX93200.1 - 0.071 13.7 5.0 71 4.6 0.1 5.2 5 0 0 5 5 5 0 Leucine Rich Repeat DUF2105 PF09878.9 ORX93200.1 - 0.13 11.9 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2105) TPR_12 PF13424.6 ORX93200.1 - 0.22 11.8 1.3 8.6 6.7 0.3 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat LRR_6 PF13516.6 ORX93200.1 - 0.73 10.0 9.3 56 4.2 0.3 5.2 5 0 0 5 5 5 0 Leucine Rich repeat SNF2_N PF00176.23 ORX93201.1 - 5.1e-64 216.2 0.1 9.2e-64 215.3 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ORX93201.1 - 2.6e-17 63.2 0.0 1.7e-16 60.6 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORX93201.1 - 6.6e-09 36.0 0.0 1.8e-08 34.6 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HSA PF07529.13 ORX93201.1 - 6e-06 26.5 5.3 6e-06 26.5 5.3 2.3 1 1 1 2 2 2 1 HSA DEAD PF00270.29 ORX93201.1 - 0.00041 20.2 0.0 0.00081 19.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DEAD_2 PF06733.15 ORX93201.1 - 0.0056 16.3 0.0 0.013 15.1 0.0 1.5 1 0 0 1 1 1 1 DEAD_2 NDUF_B8 PF05821.11 ORX93202.1 - 3.3e-09 36.9 0.4 4e-09 36.6 0.4 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) Cupin_1 PF00190.22 ORX93203.1 - 5.7e-05 22.8 0.0 0.00018 21.1 0.0 1.6 1 1 1 2 2 2 1 Cupin Cupin_2 PF07883.11 ORX93203.1 - 0.00012 21.7 0.3 0.00031 20.4 0.3 1.6 1 1 0 1 1 1 1 Cupin domain Cupin_6 PF12852.7 ORX93203.1 - 0.014 15.1 0.1 0.024 14.4 0.1 1.4 1 1 0 1 1 1 0 Cupin ARD PF03079.14 ORX93203.1 - 0.052 13.7 0.0 0.085 13.0 0.0 1.3 1 0 0 1 1 1 0 ARD/ARD' family AraC_binding PF02311.19 ORX93203.1 - 0.054 13.4 0.2 0.084 12.8 0.2 1.2 1 0 0 1 1 1 0 AraC-like ligand binding domain GPI PF06560.11 ORX93203.1 - 0.16 11.2 0.0 0.22 10.8 0.0 1.1 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) IHO1 PF15771.5 ORX93204.1 - 0.034 12.9 8.3 0.048 12.4 8.3 1.2 1 0 0 1 1 1 0 Interactor of HORMAD1 protein 1 Red1 PF07964.11 ORX93204.1 - 4 5.6 13.2 5.8 5.0 13.2 1.1 1 0 0 1 1 1 0 Rec10 / Red1 FAD-oxidase_C PF02913.19 ORX93205.1 - 1.2e-62 211.8 0.6 2.3e-62 210.9 0.6 1.5 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 ORX93205.1 - 4.1e-37 127.0 0.0 9.5e-37 125.8 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain Glyco_transf_28 PF03033.20 ORX93206.1 - 2.2e-17 63.4 0.0 2.1e-10 40.8 0.0 2.7 2 0 0 2 2 2 2 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 ORX93206.1 - 2.5e-08 33.2 0.0 4.3e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase ATG_C PF09333.11 ORX93206.1 - 0.0017 18.7 0.0 0.0054 17.0 0.0 1.8 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain Glyco_tran_28_C PF04101.16 ORX93206.1 - 0.0017 18.3 0.1 0.0053 16.8 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase family 28 C-terminal domain PT PF04886.12 ORX93218.1 - 3.5e-16 58.5 35.1 1.9e+03 -1.5 35.1 4.6 1 1 0 1 1 1 0 PT repeat DUF1069 PF06370.11 ORX93218.1 - 1.1 8.8 4.3 14 5.2 0.4 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1069) Baculo_LEF-10 PF07206.11 ORX93219.1 - 1.3 9.2 4.7 0.97 9.6 0.3 2.6 2 0 0 2 2 2 0 Baculovirus late expression factor 10 (LEF-10) F-box PF00646.33 ORX93220.1 - 4.8e-09 35.9 0.0 1.2e-08 34.6 0.0 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 ORX93220.1 - 4.8e-08 32.8 0.0 1.2e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 F-box-like DNA_pol_B_palm PF14792.6 ORX93221.1 - 1.4e-31 109.1 0.0 3.5e-31 107.8 0.0 1.7 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.6 ORX93221.1 - 6.1e-23 80.8 0.1 1.2e-22 79.8 0.1 1.5 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.9 ORX93221.1 - 1.7e-18 66.2 0.1 5.3e-18 64.6 0.1 2.0 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.6 ORX93221.1 - 2.1e-16 60.0 0.1 4.1e-16 59.1 0.1 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain NTP_transf_2 PF01909.23 ORX93221.1 - 0.11 12.8 0.0 0.31 11.3 0.0 1.7 1 0 0 1 1 1 0 Nucleotidyltransferase domain CAP59_mtransfer PF11735.8 ORX93222.1 - 4.2e-69 232.9 0.0 5e-69 232.6 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 CHS5_N PF16892.5 ORX93222.1 - 0.19 11.7 0.0 0.38 10.8 0.0 1.4 1 0 0 1 1 1 0 Chitin biosynthesis protein CHS5 N-terminus HET PF06985.11 ORX93224.1 - 2.9e-17 63.4 0.0 5.3e-17 62.5 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ATP-synt_10 PF05176.14 ORX93225.1 - 6.1e-75 251.8 0.0 7.8e-75 251.4 0.0 1.1 1 0 0 1 1 1 1 ATP10 protein PI3K_rbd PF00794.18 ORX93225.1 - 0.027 14.6 0.0 0.058 13.6 0.0 1.5 1 0 0 1 1 1 0 PI3-kinase family, ras-binding domain V-SNARE_C PF12352.8 ORX93226.1 - 2.9e-14 53.1 0.1 2.9e-14 53.1 0.1 2.6 2 1 1 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Vps54_N PF10475.9 ORX93226.1 - 0.066 12.5 1.5 0.11 11.8 0.7 1.6 1 1 1 2 2 2 0 Vacuolar-sorting protein 54, of GARP complex JAKMIP_CC3 PF16034.5 ORX93226.1 - 0.067 13.1 6.0 0.1 12.5 6.0 1.2 1 0 0 1 1 1 0 JAKMIP CC3 domain Syntaxin-6_N PF09177.11 ORX93226.1 - 0.43 11.2 4.9 0.29 11.7 3.0 1.7 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Syntaxin_2 PF14523.6 ORX93226.1 - 0.88 10.0 4.3 5.1 7.5 4.3 2.1 1 1 0 1 1 1 0 Syntaxin-like protein Ribosomal_L29 PF00831.23 ORX93227.1 - 1.2e-16 60.4 0.4 1.2e-16 60.4 0.4 2.1 2 0 0 2 2 2 1 Ribosomal L29 protein GHMP_kinases_N PF00288.26 ORX93228.1 - 3.7e-15 55.9 2.7 9e-15 54.7 2.4 1.8 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 ORX93228.1 - 2.1e-08 34.4 0.1 1.8e-07 31.4 0.1 2.2 1 1 0 1 1 1 1 GHMP kinases C terminal LRRFIP PF09738.9 ORX93228.1 - 0.083 12.4 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 LRRFIP family PPR_2 PF13041.6 ORX93229.1 - 6.4e-43 144.7 6.5 1e-08 35.3 0.0 14.1 12 4 4 16 16 16 9 PPR repeat family PPR_3 PF13812.6 ORX93229.1 - 4.3e-35 119.6 0.1 0.0012 18.8 0.0 10.9 7 2 2 10 10 10 9 Pentatricopeptide repeat domain PPR_long PF17177.4 ORX93229.1 - 2.8e-22 79.1 5.2 2e-07 30.6 0.0 5.9 4 1 1 5 5 5 4 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 ORX93229.1 - 1.2e-21 76.1 5.0 1.3e-06 28.0 0.0 10.7 11 1 0 11 11 11 5 PPR repeat PPR PF01535.20 ORX93229.1 - 6.7e-18 63.6 28.6 0.00067 19.7 0.0 15.2 18 1 0 18 18 18 4 PPR repeat RPM2 PF08579.11 ORX93229.1 - 0.00087 19.7 0.0 0.1 13.0 0.0 3.3 3 0 0 3 3 3 1 Mitochondrial ribonuclease P subunit (RPM2) zf-C2H2_6 PF13912.6 ORX93232.1 - 5.4e-07 29.5 0.6 0.013 15.5 0.0 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORX93232.1 - 1.5e-06 28.4 0.8 1.5e-06 28.4 0.8 3.5 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2 PF00096.26 ORX93232.1 - 3.8e-06 27.0 0.5 3.8e-06 27.0 0.5 3.6 3 2 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORX93232.1 - 0.00082 20.0 7.5 0.0017 19.0 0.4 2.9 3 0 0 3 3 3 1 C2H2-type zinc finger FOXP-CC PF16159.5 ORX93232.1 - 0.00088 19.9 11.3 0.1 13.2 1.9 3.2 3 1 1 4 4 4 2 FOXP coiled-coil domain zf-C2H2_11 PF16622.5 ORX93232.1 - 0.16 11.8 0.3 0.62 9.9 0.0 2.0 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 ORX93232.1 - 0.19 12.1 0.6 2.2 8.7 0.1 2.5 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 ORX93232.1 - 9.7 6.0 7.6 0.74 9.6 0.1 2.6 3 0 0 3 3 3 0 C2H2-type zinc-finger domain Aldo_ket_red PF00248.21 ORX93233.1 - 8.4e-05 21.9 0.0 9.9e-05 21.7 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family HetR_C PF18460.1 ORX93233.1 - 0.13 12.2 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 Heterocyst differentiation regulator C-terminal Hood domain HET PF06985.11 ORX93266.1 - 1.8e-14 54.3 0.0 2.8e-14 53.7 0.0 1.3 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) AidB_N PF18158.1 ORX93267.1 - 1.1e-12 48.1 0.0 2.7e-12 46.9 0.0 1.6 1 1 0 1 1 1 1 Adaptive response protein AidB N-terminal domain Acyl-CoA_dh_1 PF00441.24 ORX93267.1 - 1.4e-12 48.0 0.1 5.9e-12 46.0 0.1 1.9 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 ORX93267.1 - 1.3e-10 41.3 0.0 6.4e-10 39.1 0.0 2.3 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain DUF3543 PF12063.8 ORX93269.1 - 0.093 12.1 0.0 0.097 12.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3543) Amidohydro_3 PF07969.11 ORX93270.1 - 4.2e-52 178.2 4.0 4.9e-52 178.0 4.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 ORX93270.1 - 6.4e-16 58.6 2.3 1e-14 54.6 0.6 2.5 2 1 0 2 2 2 2 Amidohydrolase family SpoVS PF04232.12 ORX93270.1 - 0.083 12.6 0.1 0.33 10.7 0.1 2.0 1 0 0 1 1 1 0 Stage V sporulation protein S (SpoVS) IBR PF01485.21 ORX93271.1 - 0.0074 16.5 26.4 0.24 11.6 6.2 2.7 1 1 1 2 2 2 2 IBR domain, a half RING-finger domain F-box-like PF12937.7 ORX93273.1 - 0.0026 17.6 0.4 0.35 10.8 0.0 3.4 4 0 0 4 4 4 2 F-box-like Aldedh PF00171.22 ORX93281.1 - 2.4e-77 260.4 0.0 2.9e-77 260.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Cyt_bd_oxida_II PF02322.15 ORX93281.1 - 0.057 12.8 0.6 0.091 12.1 0.6 1.2 1 0 0 1 1 1 0 Cytochrome bd terminal oxidase subunit II TcA_TcB_BD PF18276.1 ORX93282.1 - 5.9e-100 334.1 0.0 9.1e-100 333.4 0.0 1.3 1 0 0 1 1 1 1 Tc toxin complex TcA C-terminal TcB-binding domain Neuraminidase PF18413.1 ORX93282.1 - 1.4e-20 73.6 0.4 3.4e-20 72.4 0.4 1.6 1 0 0 1 1 1 1 Neuraminidase-like domain VRP1 PF03538.14 ORX93282.1 - 2.8e-05 23.7 0.0 7.9e-05 22.2 0.0 1.7 2 0 0 2 2 2 1 Salmonella virulence plasmid 28.1kDa A protein Ax_dynein_light PF10211.9 ORX93282.1 - 0.17 11.8 4.7 1.3 8.9 0.1 3.3 4 0 0 4 4 4 0 Axonemal dynein light chain SpvB PF03534.13 ORX93283.1 - 1e-84 284.2 4.2 1.1e-51 175.7 0.0 3.1 2 1 1 3 3 3 2 Salmonella virulence plasmid 65kDa B protein TcdB_toxin_midN PF12256.8 ORX93283.1 - 7.5e-23 80.8 2.7 1.9e-18 66.5 0.0 5.7 5 1 1 6 6 6 1 Insecticide toxin TcdB middle/N-terminal region TcdB_toxin_midC PF12255.8 ORX93283.1 - 4.4e-15 56.0 0.1 8.9e-15 55.0 0.1 1.5 1 0 0 1 1 1 1 Insecticide toxin TcdB middle/C-terminal region VCBS PF13517.6 ORX93283.1 - 5.9e-06 26.8 12.1 0.0016 19.0 3.8 4.4 2 2 1 3 3 3 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella RHS_repeat PF05593.14 ORX93283.1 - 0.00082 19.8 17.4 0.52 10.9 0.2 8.4 7 2 1 8 8 8 2 RHS Repeat Phage_holin_3_6 PF07332.11 ORX93283.1 - 0.47 10.5 2.4 0.81 9.8 2.4 1.3 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III F-box-like PF12937.7 ORX93284.1 - 6e-07 29.3 1.2 1.3e-05 24.9 1.2 2.5 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 ORX93284.1 - 0.018 14.9 1.3 5 7.1 0.2 2.8 2 0 0 2 2 2 0 F-box domain LRR_4 PF12799.7 ORX93284.1 - 1.5 9.3 4.7 52 4.4 0.3 4.0 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) 4HBT PF03061.22 ORX93285.1 - 1.7e-08 34.6 0.1 3.6e-08 33.7 0.1 1.5 1 1 0 1 1 1 1 Thioesterase superfamily BRCT PF00533.26 ORX93286.1 - 6e-21 74.6 0.1 2.5e-06 27.7 0.0 3.2 3 0 0 3 3 3 3 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 ORX93286.1 - 2.1e-10 40.4 0.2 0.036 14.0 0.0 3.4 3 0 0 3 3 3 3 twin BRCT domain Glyco_trans_1_4 PF13692.6 ORX93286.1 - 1e-05 26.0 0.2 0.3 11.5 0.0 3.2 3 0 0 3 3 3 1 Glycosyl transferases group 1 YL1 PF05764.13 ORX93286.1 - 8.5e-05 22.8 10.1 0.00012 22.3 10.1 1.3 1 0 0 1 1 1 1 YL1 nuclear protein SLAM PF06214.11 ORX93286.1 - 0.0001 22.3 0.2 9.1 6.3 0.0 3.2 3 0 0 3 3 3 0 Signaling lymphocytic activation molecule (SLAM) protein Glycos_transf_1 PF00534.20 ORX93286.1 - 0.00023 20.7 2.4 1.1 8.7 0.4 3.3 3 0 0 3 3 3 1 Glycosyl transferases group 1 DUF2890 PF11081.8 ORX93286.1 - 0.0086 16.2 1.3 0.015 15.4 1.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2890) MlrC_C PF07171.12 ORX93286.1 - 0.03 14.5 0.0 5.8 7.0 0.0 2.9 3 0 0 3 3 3 0 MlrC C-terminus Bep_C_terminal PF17841.1 ORX93286.1 - 0.039 14.2 1.0 7.5 6.9 0.0 2.8 3 0 0 3 3 2 0 BID domain of Bartonella effector protein (Bep) CDC45 PF02724.14 ORX93286.1 - 0.04 12.2 7.0 0.049 11.9 7.0 1.1 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 ORX93286.1 - 0.044 13.1 8.6 0.059 12.7 8.6 1.2 1 0 0 1 1 1 0 NOA36 protein SDA1 PF05285.12 ORX93286.1 - 0.12 11.8 15.1 0.17 11.3 15.1 1.2 1 0 0 1 1 1 0 SDA1 Tub_N PF16322.5 ORX93286.1 - 0.12 12.8 9.0 0.19 12.1 9.0 1.4 1 0 0 1 1 1 0 Tubby N-terminal BRCT_2 PF16589.5 ORX93286.1 - 0.15 12.5 1.0 41 4.7 0.0 3.2 3 0 0 3 3 3 0 BRCT domain, a BRCA1 C-terminus domain NtA PF03146.15 ORX93286.1 - 0.16 11.8 0.1 6.5 6.7 0.0 2.8 3 0 0 3 3 3 0 Agrin NtA domain Merozoite_SPAM PF07133.11 ORX93286.1 - 0.17 11.8 23.6 0.25 11.3 23.6 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Glyco_hydro_125 PF06824.11 ORX93286.1 - 0.17 10.7 0.0 0.32 9.8 0.0 1.4 1 0 0 1 1 1 0 Metal-independent alpha-mannosidase (GH125) DUF2457 PF10446.9 ORX93286.1 - 0.3 10.2 13.5 0.5 9.5 13.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nop14 PF04147.12 ORX93286.1 - 0.38 8.9 15.9 0.48 8.6 15.9 1.1 1 0 0 1 1 1 0 Nop14-like family DUF4589 PF15252.6 ORX93286.1 - 0.5 10.3 2.8 0.85 9.6 2.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4589) CENP-B_dimeris PF09026.10 ORX93286.1 - 1 9.8 19.3 1.8 9.0 19.3 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Myc_N PF01056.18 ORX93286.1 - 1.2 9.0 6.7 1.6 8.5 6.7 1.3 1 0 0 1 1 1 0 Myc amino-terminal region PBP1_TM PF14812.6 ORX93286.1 - 1.2 9.6 9.1 2.7 8.4 9.1 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Drc1-Sld2 PF11719.8 ORX93286.1 - 1.3 8.5 10.3 1.7 8.1 10.3 1.1 1 0 0 1 1 1 0 DNA replication and checkpoint protein RNA_pol_Rpc4 PF05132.14 ORX93286.1 - 1.4 9.3 6.3 2.4 8.6 6.3 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 eIF3_subunit PF08597.10 ORX93286.1 - 2.1 8.2 20.4 3.5 7.5 20.4 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit RPN2_C PF18004.1 ORX93286.1 - 2.9 7.8 11.4 4.7 7.1 11.4 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain RR_TM4-6 PF06459.12 ORX93286.1 - 3.3 7.5 10.0 4.6 7.0 10.0 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Paf1 PF03985.13 ORX93286.1 - 3.5 6.5 15.0 4.8 6.1 15.0 1.1 1 0 0 1 1 1 0 Paf1 DUF913 PF06025.12 ORX93286.1 - 3.6 6.5 5.6 5.5 5.9 5.6 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) GEN1_C PF18380.1 ORX93286.1 - 7.1 7.6 10.4 18 6.3 10.4 1.7 1 0 0 1 1 1 0 Holliday junction resolvase Gen1 C-terminal domain DNA_pol_phi PF04931.13 ORX93286.1 - 7.6 4.5 19.4 10 4.1 19.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi 2-Hacid_dh_C PF02826.19 ORX93307.1 - 2.1e-52 177.1 0.0 3.5e-52 176.3 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 ORX93307.1 - 9e-37 125.7 0.0 1.2e-36 125.3 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AdoHcyase_NAD PF00670.21 ORX93307.1 - 8e-05 22.8 0.0 0.0002 21.5 0.0 1.6 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_2 PF03446.15 ORX93307.1 - 0.00052 20.2 0.1 0.0012 19.1 0.1 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 ORX93307.1 - 0.0046 16.5 0.1 0.026 14.1 0.0 2.1 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain DUF4440 PF14534.6 ORX93307.1 - 0.11 12.9 0.0 0.29 11.5 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) 3HCDH_N PF02737.18 ORX93307.1 - 0.11 12.3 0.2 0.67 9.8 0.2 2.2 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ACT PF01842.25 ORX93307.1 - 0.12 12.2 0.1 0.44 10.4 0.0 2.1 2 0 0 2 2 2 0 ACT domain G6PD_C PF02781.16 ORX93308.1 - 5.9e-114 380.1 0.0 9.2e-114 379.5 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 ORX93308.1 - 1.7e-60 204.7 0.0 3.1e-60 203.8 0.0 1.4 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Ribosomal_L35Ae PF01247.18 ORX93309.1 - 4.6e-44 148.5 0.4 5.2e-44 148.3 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 ORX93309.1 - 6e-06 26.4 0.0 0.019 15.2 0.0 2.1 2 0 0 2 2 2 2 RimM N-terminal domain Glyco_hydro_4C PF11975.8 ORX93310.1 - 0.071 13.2 0.0 7.8 6.5 0.0 2.0 2 0 0 2 2 2 0 Family 4 glycosyl hydrolase C-terminal domain RRM_1 PF00076.22 ORX93313.1 - 1.2e-20 73.1 0.0 3.6e-13 49.1 0.0 2.7 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 ORX93313.1 - 0.0011 18.8 0.0 0.0065 16.3 0.0 2.2 2 0 0 2 2 2 1 Occluded RNA-recognition motif Limkain-b1 PF11608.8 ORX93313.1 - 0.047 13.8 0.1 0.23 11.5 0.1 2.3 3 1 0 3 3 3 0 Limkain b1 RRM_5 PF13893.6 ORX93313.1 - 0.092 12.3 0.0 14 5.3 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MFS_2 PF13347.6 ORX93314.1 - 3e-12 45.8 5.5 3e-12 45.8 5.5 2.1 2 1 0 2 2 2 1 MFS/sugar transport protein MFS_1_like PF12832.7 ORX93314.1 - 1.4e-05 24.2 0.0 3e-05 23.1 0.0 1.7 1 1 0 1 1 1 1 MFS_1 like family Nuc_H_symport PF03825.16 ORX93314.1 - 0.024 13.6 0.4 0.024 13.6 0.4 2.3 3 0 0 3 3 3 0 Nucleoside H+ symporter NAP PF00956.18 ORX93315.1 - 1.1e-98 329.8 9.3 1.1e-98 329.8 9.3 1.6 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) AAA_18 PF13238.6 ORX93316.1 - 4e-26 92.1 0.2 8.2e-26 91.1 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 ORX93316.1 - 1.4e-08 35.2 0.2 2e-07 31.5 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 ORX93316.1 - 3.6e-06 27.2 0.0 0.00096 19.3 0.0 2.3 1 1 0 2 2 2 1 AAA domain ADK PF00406.22 ORX93316.1 - 1.8e-05 24.9 0.1 0.0017 18.5 0.0 2.1 2 0 0 2 2 2 1 Adenylate kinase dNK PF01712.19 ORX93316.1 - 3.2e-05 23.9 0.5 0.22 11.3 0.0 2.2 2 0 0 2 2 2 2 Deoxynucleoside kinase AAA_28 PF13521.6 ORX93316.1 - 6.6e-05 23.2 0.7 0.0006 20.1 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA PF00004.29 ORX93316.1 - 6.6e-05 23.3 0.0 0.00016 22.1 0.0 1.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 ORX93316.1 - 0.00021 21.3 0.1 0.00041 20.3 0.0 1.6 2 0 0 2 2 2 1 NTPase KTI12 PF08433.10 ORX93316.1 - 0.00075 19.0 0.0 0.0016 17.9 0.0 1.5 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA_16 PF13191.6 ORX93316.1 - 0.002 18.5 0.1 0.0031 17.9 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain Hydin_ADK PF17213.3 ORX93316.1 - 0.0026 18.1 0.0 0.004 17.5 0.0 1.3 1 0 0 1 1 1 1 Hydin Adenylate kinase-like domain Thymidylate_kin PF02223.17 ORX93316.1 - 0.0026 17.5 0.0 1.8 8.2 0.0 2.2 2 0 0 2 2 2 2 Thymidylate kinase SKI PF01202.22 ORX93316.1 - 0.0036 17.4 0.3 0.21 11.7 0.3 2.3 1 1 0 1 1 1 1 Shikimate kinase AAA_22 PF13401.6 ORX93316.1 - 0.0061 16.8 0.0 0.017 15.4 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 ORX93316.1 - 0.0082 15.9 0.0 0.016 15.0 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 ORX93316.1 - 0.022 14.8 0.0 0.04 14.0 0.0 1.5 2 0 0 2 2 1 0 AAA domain NACHT PF05729.12 ORX93316.1 - 0.023 14.6 0.1 0.083 12.8 0.0 1.8 2 0 0 2 2 2 0 NACHT domain RuvB_N PF05496.12 ORX93316.1 - 0.025 14.3 0.0 0.045 13.5 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 ORX93316.1 - 0.029 14.8 0.0 0.044 14.2 0.0 1.3 1 0 0 1 1 1 0 RNA helicase AAA_19 PF13245.6 ORX93316.1 - 0.036 14.4 0.1 0.068 13.5 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 ORX93316.1 - 0.038 14.0 0.0 0.07 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Cytidylate_kin2 PF13189.6 ORX93316.1 - 0.055 13.6 0.0 0.23 11.6 0.0 1.9 2 0 0 2 2 2 0 Cytidylate kinase-like family AAA_3 PF07726.11 ORX93316.1 - 0.073 12.9 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 ORX93316.1 - 0.076 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Viral_helicase1 PF01443.18 ORX93316.1 - 0.093 12.5 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase MeaB PF03308.16 ORX93316.1 - 0.12 11.3 0.5 0.21 10.6 0.1 1.6 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 ORX93316.1 - 0.15 11.8 1.9 3.9 7.1 1.0 2.2 1 1 1 2 2 2 0 AAA domain Ham1p_like PF01725.16 ORX93317.1 - 5.3e-58 196.0 0.0 6e-58 195.9 0.0 1.0 1 0 0 1 1 1 1 Ham1 family p450 PF00067.22 ORX93318.1 - 0.01 14.6 0.0 0.094 11.4 0.0 2.3 2 0 0 2 2 2 0 Cytochrome P450 3Beta_HSD PF01073.19 ORX93340.1 - 1.1e-32 113.2 0.0 1.5e-32 112.8 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 ORX93340.1 - 4.7e-18 65.5 0.0 6.5e-18 65.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 ORX93340.1 - 8.4e-10 38.2 0.0 6.5e-05 22.2 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein GDP_Man_Dehyd PF16363.5 ORX93340.1 - 1.1e-08 34.8 0.0 1.9e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 ORX93340.1 - 0.0014 17.8 0.0 0.0052 15.9 0.0 1.9 1 1 0 1 1 1 1 RmlD substrate binding domain KR PF08659.10 ORX93340.1 - 0.0074 16.2 0.9 0.044 13.7 0.4 2.5 1 1 1 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 ORX93340.1 - 0.017 14.3 0.0 0.12 11.5 0.0 2.3 2 1 0 2 2 2 0 Polysaccharide biosynthesis protein 2Fe-2S_thioredx PF01257.19 ORX93341.1 - 4.1e-62 208.3 0.1 5.2e-62 208.0 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin UDPG_MGDP_dh PF00984.19 ORX93341.1 - 0.031 14.5 0.0 0.44 10.8 0.0 2.2 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, central domain TauD PF02668.16 ORX93342.1 - 8.6e-46 156.9 0.4 1.3e-43 149.8 0.4 2.1 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.16 ORX93343.1 - 2.6e-33 115.4 12.3 4.2e-33 114.7 12.3 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily FMO-like PF00743.19 ORX93343.1 - 3.9e-26 91.6 0.0 1.2e-13 50.3 0.0 3.9 2 1 1 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 ORX93343.1 - 3.3e-16 59.4 0.0 2.9e-11 43.2 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ORX93343.1 - 1.8e-11 43.8 0.0 7.3e-11 41.8 0.0 2.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORX93343.1 - 5e-10 39.5 0.3 1.4e-08 34.8 0.0 2.9 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 ORX93343.1 - 2e-06 27.9 0.1 9.5e-05 22.4 0.2 2.9 2 1 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.24 ORX93343.1 - 1e-05 25.3 4.4 0.00016 21.4 3.1 2.8 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 ORX93343.1 - 0.00014 21.4 0.0 0.00034 20.1 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 ORX93343.1 - 0.00035 20.0 0.1 0.001 18.5 0.0 1.8 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 ORX93343.1 - 0.00051 20.5 0.9 0.0026 18.3 0.9 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ORX93343.1 - 0.00085 18.5 0.4 0.0014 17.8 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 ORX93343.1 - 0.0013 18.0 0.4 0.0026 17.0 0.4 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 ORX93343.1 - 0.002 16.9 0.8 0.0039 15.9 0.8 1.5 1 0 0 1 1 1 1 HI0933-like protein ApbA PF02558.16 ORX93343.1 - 0.0099 15.5 0.0 0.033 13.8 0.0 1.9 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA GIDA PF01134.22 ORX93343.1 - 0.014 14.5 2.1 0.03 13.4 2.1 1.5 1 0 0 1 1 1 0 Glucose inhibited division protein A Thi4 PF01946.17 ORX93343.1 - 0.018 14.3 1.2 0.025 13.8 0.3 1.6 2 0 0 2 2 2 0 Thi4 family AlaDh_PNT_C PF01262.21 ORX93343.1 - 0.03 13.6 0.3 0.054 12.8 0.3 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 ORX93343.1 - 0.12 12.2 1.1 0.23 11.3 1.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 ORX93343.1 - 0.13 12.5 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 ORX93343.1 - 0.15 11.6 0.2 0.31 10.6 0.2 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain FAD_binding_4 PF01565.23 ORX93345.1 - 6.3e-21 74.6 2.7 9.2e-21 74.0 2.7 1.2 1 0 0 1 1 1 1 FAD binding domain DUF1223 PF06764.11 ORX93373.1 - 1.4e-20 74.2 0.0 2.1e-20 73.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1223) Zn_clus PF00172.18 ORX93374.1 - 7e-10 38.9 10.9 1.1e-09 38.2 10.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HET PF06985.11 ORX93375.1 - 3.4e-05 24.2 0.0 6.3e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) TPR_14 PF13428.6 ORX93375.1 - 0.062 14.1 0.2 0.88 10.6 0.1 2.6 2 1 1 3 3 3 0 Tetratricopeptide repeat Peptidase_S24 PF00717.23 ORX93376.1 - 7.8e-10 38.6 0.5 7.8e-10 38.6 0.5 1.8 2 1 0 2 2 2 1 Peptidase S24-like DNase_NucA_NucB PF14040.6 ORX93378.1 - 0.00026 21.3 0.9 0.00057 20.2 0.9 1.6 1 0 0 1 1 1 1 Deoxyribonuclease NucA/NucB GP67 PF17634.2 ORX93422.1 - 1.3 9.5 17.5 0.22 11.9 1.6 2.3 2 0 0 2 2 2 0 Gene product 67 CobT PF06213.12 ORX93422.1 - 2 7.7 13.1 2.4 7.5 13.1 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT ORC6 PF05460.13 ORX93422.1 - 6.8 5.8 17.5 8.2 5.6 17.5 1.0 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Presenilin PF01080.17 ORX93422.1 - 9.2 4.9 10.1 10 4.8 10.1 1.2 1 0 0 1 1 1 0 Presenilin HTH_psq PF05225.16 ORX93460.1 - 0.083 12.6 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 helix-turn-helix, Psq domain zf-piccolo PF05715.13 ORX93461.1 - 0.45 10.7 12.5 0.22 11.7 3.4 2.7 2 0 0 2 2 2 0 Piccolo Zn-finger DUF676 PF05057.14 ORX93463.1 - 4.4e-05 23.1 0.0 0.0002 21.0 0.0 1.9 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 ORX93463.1 - 0.00042 21.0 0.0 0.00065 20.4 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORX93463.1 - 0.0016 17.7 0.0 0.0036 16.6 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 ORX93463.1 - 0.047 13.8 0.0 0.079 13.1 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain PGAP1 PF07819.13 ORX93463.1 - 0.055 13.2 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein Lipase_3 PF01764.25 ORX93463.1 - 0.072 13.0 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) LCAT PF02450.15 ORX93463.1 - 0.081 12.1 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase NACHT PF05729.12 ORX93464.1 - 0.00035 20.5 0.2 0.0011 18.9 0.2 1.9 1 1 0 1 1 1 1 NACHT domain CENP-B_dimeris PF09026.10 ORX93464.1 - 0.0052 17.1 11.1 0.011 16.1 11.1 1.5 1 0 0 1 1 1 1 Centromere protein B dimerisation domain AAA_16 PF13191.6 ORX93464.1 - 0.0084 16.5 0.0 0.027 14.9 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 ORX93464.1 - 0.046 14.3 0.5 0.5 10.9 0.0 2.9 3 0 0 3 3 3 0 AAA domain P22_Tail-4 PF11650.8 ORX93464.1 - 0.064 13.2 1.1 0.12 12.4 0.0 2.0 2 1 0 2 2 2 0 P22 tail accessory factor NOA36 PF06524.12 ORX93464.1 - 3.5 6.9 8.8 5.6 6.2 8.8 1.3 1 0 0 1 1 1 0 NOA36 protein SDA1 PF05285.12 ORX93464.1 - 7.6 5.9 6.8 12 5.2 6.8 1.2 1 0 0 1 1 1 0 SDA1 zf-C2H2_4 PF13894.6 ORX93465.1 - 0.032 15.1 4.6 0.59 11.1 0.6 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 ORX93465.1 - 0.32 11.5 9.6 0.75 10.4 0.3 3.0 2 1 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_11 PF16622.5 ORX93465.1 - 0.52 10.1 1.8 1.3 8.8 1.8 1.6 1 1 0 1 1 1 0 zinc-finger C2H2-type zf-BED PF02892.15 ORX93466.1 - 0.0004 20.3 7.2 0.0046 16.9 0.2 3.0 3 0 0 3 3 3 2 BED zinc finger zf-C2H2 PF00096.26 ORX93466.1 - 0.003 17.9 0.7 0.003 17.9 0.7 4.0 3 1 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORX93466.1 - 0.0036 18.0 0.3 0.0036 18.0 0.3 4.6 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 ORX93466.1 - 0.018 15.0 2.1 0.06 13.4 0.1 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-Di19 PF05605.12 ORX93466.1 - 0.097 13.0 2.1 0.46 10.8 0.4 2.9 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-RING_4 PF14570.6 ORX93466.1 - 1.6 8.6 6.4 0.6 9.9 0.9 2.5 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C2H2_4 PF13894.6 ORX93468.1 - 0.00011 22.7 4.4 0.33 11.9 0.5 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORX93468.1 - 0.011 16.1 1.1 0.011 16.1 1.1 3.2 4 0 0 4 4 4 0 Zinc-finger double domain zf-C2H2 PF00096.26 ORX93468.1 - 0.012 16.1 10.7 0.42 11.2 0.4 3.5 2 1 0 2 2 2 0 Zinc finger, C2H2 type zf-Di19 PF05605.12 ORX93468.1 - 0.054 13.8 0.9 0.1 12.9 0.9 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 ORX93468.1 - 0.14 12.2 3.7 1.1 9.3 0.2 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger Ribosomal_L37ae PF01780.19 ORX93468.1 - 1 9.5 3.1 2.2 8.4 0.4 2.2 1 1 1 2 2 2 0 Ribosomal L37ae protein family zf-met PF12874.7 ORX93468.1 - 2.1 8.9 5.0 5.9 7.4 0.1 3.3 3 1 0 3 3 3 0 Zinc-finger of C2H2 type FYVE PF01363.21 ORX93468.1 - 3.3 7.9 6.8 14 5.9 0.6 2.7 2 1 1 3 3 3 0 FYVE zinc finger DUF3746 PF12562.8 ORX93469.1 - 0.022 14.6 0.3 0.046 13.6 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3746) zf-FLZ PF04570.14 ORX93469.1 - 0.023 14.2 0.3 0.046 13.2 0.3 1.4 1 0 0 1 1 1 0 zinc-finger of the FCS-type, C2-C2 Actin PF00022.19 ORX93470.1 - 7.7e-29 100.5 0.0 6.3e-28 97.5 0.0 2.2 2 1 0 2 2 2 1 Actin PilM_2 PF11104.8 ORX93470.1 - 0.075 12.0 0.0 11 5.0 0.0 2.1 2 0 0 2 2 2 0 Type IV pilus assembly protein PilM; Nop PF01798.18 ORX93471.1 - 6.6e-81 271.1 0.4 6.6e-81 271.1 0.4 1.9 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 ORX93471.1 - 4.1e-19 68.7 2.3 4.1e-19 68.7 2.3 2.5 3 0 0 3 3 3 1 NOP5NT (NUC127) domain DUF760 PF05542.11 ORX93471.1 - 0.11 12.9 0.1 0.92 9.9 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF760) RNA_pol_Rpb4 PF03874.16 ORX93472.1 - 3.5e-16 59.6 0.1 7.8e-16 58.5 0.0 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb4 HET PF06985.11 ORX93484.1 - 1.2e-11 45.2 8.7 7.4e-10 39.4 1.8 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) DSPc PF00782.20 ORX93485.1 - 1.8e-26 92.5 0.0 2e-24 85.9 0.0 2.3 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 ORX93485.1 - 0.026 14.1 0.0 0.042 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase CN_hydrolase PF00795.22 ORX93486.1 - 1.4e-46 159.0 0.0 1.6e-46 158.8 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Fungal_trans_2 PF11951.8 ORX93487.1 - 1.3e-51 175.6 1.9 1.7e-51 175.3 1.9 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORX93487.1 - 2e-05 24.6 12.6 4e-05 23.6 12.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SKIP_SNW PF02731.15 ORX93489.1 - 6.7e-70 233.9 2.4 6.7e-70 233.9 2.4 2.2 2 0 0 2 2 2 1 SKIP/SNW domain Dsh_C PF12316.8 ORX93489.1 - 9.3 6.6 14.7 0.78 10.1 6.1 2.4 2 0 0 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal TAFII28 PF04719.14 ORX93490.1 - 6e-25 87.2 0.2 8.2e-24 83.5 0.2 2.1 1 1 0 1 1 1 1 hTAFII28-like protein conserved region Ank_5 PF13857.6 ORX93491.1 - 1e-09 38.4 0.2 4.2e-07 30.1 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 ORX93491.1 - 1.7e-09 38.0 0.0 0.00014 22.3 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 ORX93491.1 - 2.4e-08 34.5 0.0 3.8e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 ORX93491.1 - 2.2e-06 27.8 0.1 0.0005 20.4 0.2 2.5 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 ORX93491.1 - 6.7e-06 26.1 0.0 0.02 15.4 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ribosomal_L4 PF00573.22 ORX93492.1 - 2e-31 109.1 0.8 2.8e-31 108.7 0.8 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 ORX93492.1 - 9.9e-29 99.2 0.4 3.7e-28 97.4 0.1 2.0 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain SMN PF06003.12 ORX93512.1 - 2.1 7.6 5.7 3.7 6.7 5.7 1.4 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) PROL5-SMR PF15621.6 ORX93512.1 - 2.9 8.4 18.3 7.6 7.1 18.3 1.7 1 0 0 1 1 1 0 Proline-rich submaxillary gland androgen-regulated family TRP PF06011.12 ORX93513.1 - 0.059 12.1 0.1 0.06 12.1 0.1 1.0 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel Zn_clus PF00172.18 ORX93515.1 - 2.1e-07 30.9 11.4 5.8e-07 29.5 11.4 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.25 ORX93516.1 - 6.9e-16 58.3 0.0 9.6e-16 57.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORX93516.1 - 1.1e-09 38.2 0.0 1.4e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORX93516.1 - 4.3e-07 30.0 0.8 2.1e-05 24.5 0.8 2.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 ORX93516.1 - 5.3e-05 22.8 0.0 6.6e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 ORX93516.1 - 0.00038 19.6 0.0 0.00054 19.0 0.0 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 ORX93516.1 - 0.0026 17.2 0.0 0.0046 16.4 0.0 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase ERCC3_RAD25_C PF16203.5 ORX93517.1 - 1.4e-121 404.4 0.3 2.5e-121 403.6 0.3 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 ORX93517.1 - 4.3e-30 104.5 0.0 1.2e-29 103.0 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORX93517.1 - 2.7e-16 60.0 0.0 6.4e-16 58.8 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 ORX93517.1 - 2.6e-14 53.5 0.5 1e-13 51.6 0.2 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 ORX93517.1 - 2.2e-06 26.6 0.0 3e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Hid1 PF12722.7 ORX93518.1 - 0 1044.8 0.0 0 1044.7 0.0 1.0 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 ORX93518.1 - 7.3e-110 368.2 0.0 9.1e-110 367.9 0.0 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein EHN PF06441.12 ORX93519.1 - 2.7e-18 66.3 0.0 6.1e-18 65.2 0.0 1.6 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 ORX93519.1 - 0.015 15.0 0.0 0.074 12.7 0.0 1.9 1 1 0 1 1 1 0 alpha/beta hydrolase fold SAM_decarbox PF01536.16 ORX93520.1 - 1.4e-132 442.1 0.0 2.1e-132 441.5 0.0 1.3 1 1 0 1 1 1 1 Adenosylmethionine decarboxylase WD40 PF00400.32 ORX93522.1 - 3.3e-62 204.9 23.1 6.4e-12 45.8 1.0 6.1 5 0 0 5 5 5 5 WD domain, G-beta repeat NACHT PF05729.12 ORX93522.1 - 4.5e-27 95.0 0.1 9.4e-27 94.0 0.1 1.5 1 0 0 1 1 1 1 NACHT domain ANAPC4_WD40 PF12894.7 ORX93522.1 - 6.5e-25 87.3 0.4 0.0011 19.2 0.0 5.9 2 1 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 ORX93522.1 - 9.8e-12 44.5 3.9 0.02 13.9 0.2 5.2 1 1 3 4 4 4 4 WD40 region of Ge1, enhancer of mRNA-decapping protein HET PF06985.11 ORX93522.1 - 3.1e-09 37.3 1.2 3.1e-09 37.3 1.2 3.2 2 1 1 3 3 2 2 Heterokaryon incompatibility protein (HET) Nup160 PF11715.8 ORX93522.1 - 8.7e-08 31.3 2.3 1.5 7.4 0.1 4.9 1 1 2 4 4 4 4 Nucleoporin Nup120/160 AAA_16 PF13191.6 ORX93522.1 - 0.04 14.3 0.0 0.13 12.6 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain RNA_helicase PF00910.22 ORX93522.1 - 0.05 14.0 0.0 0.15 12.4 0.0 1.8 1 0 0 1 1 1 0 RNA helicase PD40 PF07676.12 ORX93522.1 - 0.058 13.4 5.8 1.8e+02 2.2 0.0 5.7 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat DUF2075 PF09848.9 ORX93522.1 - 0.15 11.3 0.0 0.25 10.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RicinB_lectin_2 PF14200.6 ORX93522.1 - 1 10.1 3.0 75 4.2 0.0 4.1 2 1 3 5 5 5 0 Ricin-type beta-trefoil lectin domain-like Acetyltransf_1 PF00583.25 ORX93545.1 - 0.095 12.9 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family DUF4847 PF16139.5 ORX93545.1 - 0.15 11.9 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4847) DUF4632 PF15451.6 ORX93546.1 - 0.023 14.8 1.6 0.038 14.1 0.5 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4632) DUF1996 PF09362.10 ORX93548.1 - 1.4e-78 264.1 4.5 1.4e-78 264.1 4.5 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1996) HET PF06985.11 ORX93549.1 - 2.4e-08 34.4 0.0 2.8e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MuF_C PF18819.1 ORX93549.1 - 0.042 13.8 0.0 4.6 7.3 0.0 2.1 2 0 0 2 2 2 0 Phage MuF-C-terminal domain ABC_tran PF00005.27 ORX93551.1 - 3.6e-27 95.6 0.0 5.8e-27 94.9 0.0 1.3 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 ORX93551.1 - 0.0004 20.3 0.1 0.00071 19.5 0.1 1.3 1 0 0 1 1 1 1 RsgA GTPase T2SSE PF00437.20 ORX93551.1 - 0.0049 16.0 0.0 0.0079 15.3 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_29 PF13555.6 ORX93551.1 - 0.025 14.3 0.4 0.053 13.3 0.4 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 ORX93551.1 - 0.062 13.4 0.3 0.11 12.6 0.3 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_10 PF12846.7 ORX93551.1 - 0.18 10.7 0.2 0.28 10.0 0.2 1.2 1 0 0 1 1 1 0 AAA-like domain DUF87 PF01935.17 ORX93551.1 - 0.7 9.9 2.2 1.4 8.9 2.2 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain LysM PF01476.20 ORX93553.1 - 1.3e-05 25.2 0.3 0.46 10.6 0.0 3.8 3 1 0 3 3 3 3 LysM domain DUF1771 PF08590.10 ORX93577.1 - 8.3e-06 26.1 1.0 2.1e-05 24.8 1.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.21 ORX93577.1 - 0.0038 17.5 0.1 0.011 16.1 0.1 1.8 1 0 0 1 1 1 1 Smr domain CUE PF02845.16 ORX93577.1 - 0.0053 16.4 0.0 0.021 14.5 0.0 2.0 2 0 0 2 2 2 1 CUE domain HECT PF00632.25 ORX93578.1 - 3.8e-78 263.1 0.0 1.4e-77 261.2 0.0 2.0 3 0 0 3 3 3 1 HECT-domain (ubiquitin-transferase) Wap1 PF16997.5 ORX93578.1 - 0.0078 15.4 0.0 0.015 14.5 0.0 1.3 1 0 0 1 1 1 1 Wap1 domain Arm PF00514.23 ORX93578.1 - 0.053 13.6 6.1 24 5.2 0.0 5.6 5 1 1 6 6 6 0 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.20 ORX93578.1 - 0.12 10.9 2.9 0.96 7.9 0.1 2.8 3 0 0 3 3 3 0 Adaptin N terminal region CTP_transf_like PF01467.26 ORX93579.1 - 1.4e-24 86.9 0.0 1.9e-24 86.5 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase-like Cellulase PF00150.18 ORX93580.1 - 2.6e-13 50.0 0.9 2.6e-13 50.0 0.9 2.1 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Glycophorin_A PF01102.18 ORX93580.1 - 0.031 14.5 0.0 0.079 13.2 0.0 1.6 1 0 0 1 1 1 0 Glycophorin A ETRAMP PF09716.10 ORX93580.1 - 0.061 13.4 0.6 0.2 11.7 0.6 1.9 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) TMEM154 PF15102.6 ORX93580.1 - 0.18 11.7 0.0 0.58 10.1 0.0 1.8 1 0 0 1 1 1 0 TMEM154 protein family UPF0258 PF06789.12 ORX93580.1 - 0.63 10.2 2.7 2.2 8.4 1.8 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0258) EphA2_TM PF14575.6 ORX93580.1 - 2.4 9.1 0.0 2.4 9.1 0.0 3.1 3 2 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain DUF676 PF05057.14 ORX93581.1 - 7.7e-10 38.6 0.0 4.2e-09 36.3 0.0 1.9 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 ORX93581.1 - 0.0037 17.9 0.0 0.0062 17.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 ORX93581.1 - 0.06 13.1 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Tnp_DNA_bind PF14706.6 ORX93581.1 - 0.15 11.9 0.0 0.78 9.6 0.0 2.1 2 0 0 2 2 2 0 Transposase DNA-binding LCAT PF02450.15 ORX93581.1 - 0.15 11.2 0.0 0.24 10.5 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Patatin PF01734.22 ORX93582.1 - 5.6e-07 30.0 0.0 8.1e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Patatin-like phospholipase CD99L2 PF12301.8 ORX93583.1 - 0.042 14.1 0.2 0.061 13.6 0.2 1.2 1 0 0 1 1 1 0 CD99 antigen like protein 2 ADH_zinc_N PF00107.26 ORX93584.1 - 4.8e-14 52.4 0.0 8.4e-14 51.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ORX93584.1 - 3.3e-07 31.4 0.0 5.7e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ORX93584.1 - 1.8e-05 24.5 0.0 3.4e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 ORX93584.1 - 0.076 12.9 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase Med7 PF05983.11 ORX93585.1 - 9.7e-57 192.1 0.2 1.3e-56 191.7 0.2 1.2 1 0 0 1 1 1 1 MED7 protein DUF2235 PF09994.9 ORX93586.1 - 5e-55 186.9 0.0 1.4e-54 185.4 0.0 1.7 1 1 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) PhoD PF09423.10 ORX93587.1 - 6.3e-114 380.6 3.0 7.9e-114 380.3 3.0 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase PhoD_N PF16655.5 ORX93587.1 - 1.7e-34 118.2 0.4 3.6e-34 117.2 0.4 1.6 1 0 0 1 1 1 1 PhoD-like phosphatase, N-terminal domain Pur_ac_phosph_N PF16656.5 ORX93587.1 - 9.2e-06 26.2 2.3 2.6e-05 24.7 2.3 1.8 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain ADH_zinc_N_2 PF13602.6 ORX93588.1 - 1.9e-14 54.8 0.0 4.1e-14 53.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 ORX93588.1 - 4e-13 49.5 0.1 4e-13 49.5 0.1 2.0 3 0 0 3 3 3 1 Zinc-binding dehydrogenase Abhydrolase_3 PF07859.13 ORX93610.1 - 4.4e-09 36.5 0.0 2e-06 27.8 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 ORX93610.1 - 4.1e-07 29.7 0.0 2.8e-05 23.7 0.0 2.3 2 0 0 2 2 2 1 Prolyl oligopeptidase family LIP PF03583.14 ORX93610.1 - 0.0029 17.0 0.0 0.014 14.8 0.0 1.8 2 0 0 2 2 2 1 Secretory lipase DLH PF01738.18 ORX93610.1 - 0.0049 16.4 0.0 0.014 15.0 0.0 1.6 2 0 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S15 PF02129.18 ORX93610.1 - 0.02 14.5 0.0 1.5 8.3 0.0 2.3 3 0 0 3 3 3 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_2 PF02230.16 ORX93610.1 - 0.043 13.6 0.0 0.77 9.5 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase p450 PF00067.22 ORX93613.1 - 1.5e-51 175.6 0.0 2e-51 175.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Sdh_cyt PF01127.22 ORX93613.1 - 0.13 12.3 0.1 0.29 11.2 0.1 1.5 1 0 0 1 1 1 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Beta-lactamase PF00144.24 ORX93614.1 - 8.3e-44 150.2 0.0 1.2e-43 149.7 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.8 ORX93614.1 - 2.8e-06 27.7 0.0 5.5e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) FSH1 PF03959.13 ORX93615.1 - 5.8e-24 84.9 0.0 8.6e-24 84.4 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) MFS_1 PF07690.16 ORX93616.1 - 5.1e-33 114.5 51.4 6.7e-32 110.8 51.4 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily KR PF08659.10 ORX93617.1 - 9.5e-64 214.6 0.0 2e-63 213.6 0.0 1.6 1 0 0 1 1 1 1 KR domain ketoacyl-synt PF00109.26 ORX93617.1 - 9.6e-53 179.3 0.0 3.1e-52 177.7 0.0 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.6 ORX93617.1 - 1.2e-41 143.0 0.0 1.8e-41 142.3 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 ORX93617.1 - 1.7e-41 142.8 0.0 3.6e-41 141.7 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 ORX93617.1 - 1.8e-35 121.5 0.0 4.6e-35 120.2 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 ORX93617.1 - 2.8e-20 72.9 0.0 7.7e-20 71.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.6 ORX93617.1 - 3.2e-16 60.6 0.0 1.1e-14 55.7 0.0 3.1 3 0 0 3 3 3 1 Zinc-binding dehydrogenase adh_short PF00106.25 ORX93617.1 - 1.8e-12 47.1 0.0 9.3e-12 44.8 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase ADH_zinc_N PF00107.26 ORX93617.1 - 9.9e-12 45.0 0.0 3.3e-11 43.3 0.0 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase KAsynt_C_assoc PF16197.5 ORX93617.1 - 1.1e-11 45.2 0.0 5.6e-11 42.9 0.0 2.2 1 1 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_31 PF13847.6 ORX93617.1 - 1.8e-11 44.1 0.0 5.4e-11 42.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORX93617.1 - 1.9e-11 44.1 0.0 3.9e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORX93617.1 - 2.8e-11 44.0 0.1 1.3e-10 41.8 0.0 2.3 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORX93617.1 - 9.5e-11 42.2 0.0 2.8e-10 40.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORX93617.1 - 5.5e-08 32.4 0.0 1.7e-07 30.8 0.0 1.7 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family PP-binding PF00550.25 ORX93617.1 - 7.8e-08 32.6 0.3 3.4e-07 30.5 0.2 2.3 2 0 0 2 2 1 1 Phosphopantetheine attachment site ADH_N PF08240.12 ORX93617.1 - 1.5e-06 28.0 0.2 3.7e-06 26.8 0.2 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain adh_short_C2 PF13561.6 ORX93617.1 - 8.3e-05 22.2 0.0 0.00044 19.9 0.0 2.1 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase CoA_trans PF01144.23 ORX93617.1 - 0.00059 19.3 0.1 0.072 12.5 0.0 2.3 2 0 0 2 2 2 1 Coenzyme A transferase PCMT PF01135.19 ORX93617.1 - 0.036 13.8 0.0 0.13 12.0 0.0 1.9 2 0 0 2 2 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_24 PF13578.6 ORX93617.1 - 0.044 14.8 0.0 0.16 13.0 0.0 2.0 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_28 PF02636.17 ORX93617.1 - 0.18 11.4 0.0 0.34 10.5 0.0 1.4 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase FMN_dh PF01070.18 ORX93618.1 - 1.4e-87 294.0 0.0 1.3e-78 264.5 0.0 2.1 1 1 1 2 2 2 2 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 ORX93618.1 - 9.4e-17 60.9 0.0 2.5e-16 59.6 0.0 1.8 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain ZZ PF00569.17 ORX93619.1 - 0.00091 19.0 4.1 0.0015 18.3 4.1 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type BNR_2 PF13088.6 ORX93620.1 - 0.00052 19.4 0.0 0.00063 19.1 0.0 1.0 1 0 0 1 1 1 1 BNR repeat-like domain Pkinase PF00069.25 ORX93632.1 - 2.3e-12 46.8 0.0 2.5e-12 46.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX93632.1 - 1.5e-11 44.1 0.0 1.7e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 ORX93632.1 - 0.00018 21.0 0.3 0.00027 20.4 0.3 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 ORX93632.1 - 0.025 14.5 0.9 0.041 13.8 0.8 1.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.22 ORX93632.1 - 0.045 13.3 0.1 0.067 12.8 0.1 1.2 1 0 0 1 1 1 0 RIO1 family Seadorna_VP7 PF07387.11 ORX93632.1 - 0.083 11.9 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 DUF3465 PF11948.8 ORX93634.1 - 0.021 14.7 0.0 0.05 13.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3465) Ferritin_2 PF13668.6 ORX93634.1 - 0.055 13.7 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 Ferritin-like domain Keratin_B2_2 PF13885.6 ORX93635.1 - 4.8e-08 32.8 46.4 7.9e-06 25.7 23.3 3.6 2 2 1 3 3 3 2 Keratin, high sulfur B2 protein WASH-7_N PF14745.6 ORX93635.1 - 0.018 13.6 0.1 0.026 13.1 0.1 1.1 1 0 0 1 1 1 0 WASH complex subunit 7, N-terminal PMG PF05287.12 ORX93635.1 - 6.9 6.7 26.8 66 3.5 26.6 2.5 1 1 0 1 1 1 0 PMG protein DUF4199 PF13858.6 ORX93636.1 - 0.039 14.4 1.7 0.075 13.4 1.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) ResIII PF04851.15 ORX93639.1 - 0.093 12.7 0.1 0.12 12.4 0.1 1.4 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit zf-C2H2_jaz PF12171.8 ORX93643.1 - 0.013 15.7 3.0 0.013 15.7 3.0 3.5 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 ORX93643.1 - 0.095 13.0 9.8 0.21 11.9 0.1 3.0 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 ORX93643.1 - 6.8 7.8 19.5 1.8 9.6 0.6 4.1 3 1 0 3 3 3 0 C2H2-type zinc finger LAP1C PF05609.12 ORX93644.1 - 8.8 5.3 12.5 11 5.0 12.5 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) HPP PF04982.13 ORX93664.1 - 2.1e-38 131.2 4.7 2.1e-38 131.2 4.7 1.7 2 0 0 2 2 2 1 HPP family Transgly_assoc PF04226.13 ORX93664.1 - 9.1 6.6 14.6 0.61 10.4 1.8 3.1 2 1 0 2 2 2 0 Transglycosylase associated protein p450 PF00067.22 ORX93665.1 - 6.5e-82 275.7 0.0 7.4e-82 275.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 BaffR-Tall_bind PF09256.10 ORX93667.1 - 0.14 11.9 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 BAFF-R, TALL-1 binding Glyco_hydro_72 PF03198.14 ORX93669.1 - 8e-68 229.0 1.2 1.1e-67 228.5 1.2 1.2 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 ORX93669.1 - 0.0069 17.0 0.4 0.023 15.4 0.4 1.9 1 0 0 1 1 1 1 X8 domain TPR_12 PF13424.6 ORX93670.1 - 7.3e-11 42.2 0.0 0.00016 21.9 0.0 2.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 ORX93670.1 - 5.1e-07 29.4 0.0 0.0005 19.9 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 ORX93670.1 - 9.2e-07 28.5 0.0 0.1 12.7 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 ORX93670.1 - 3.3e-06 26.7 0.0 0.0011 18.6 0.0 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 ORX93670.1 - 0.00076 19.9 0.0 0.24 11.9 0.0 2.9 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_21 PF09976.9 ORX93670.1 - 0.0065 16.2 0.0 0.4 10.4 0.0 2.0 1 1 1 2 2 2 2 Tetratricopeptide repeat-like domain TPR_7 PF13176.6 ORX93670.1 - 0.0091 16.0 0.1 21 5.4 0.0 3.5 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 ORX93670.1 - 0.011 15.4 0.0 7.6 6.3 0.0 3.3 3 1 1 4 4 4 0 TPR repeat Coatomer_E PF04733.14 ORX93670.1 - 0.011 15.1 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 Coatomer epsilon subunit ANAPC3 PF12895.7 ORX93670.1 - 0.012 15.8 0.0 0.16 12.2 0.0 2.3 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 ORX93670.1 - 0.014 15.6 0.3 0.46 10.8 0.0 3.2 3 1 2 5 5 5 0 Tetratricopeptide repeat TPR_20 PF14561.6 ORX93670.1 - 0.027 14.8 0.0 8.9 6.7 0.0 2.4 2 1 0 2 2 2 0 Tetratricopeptide repeat DUF3808 PF10300.9 ORX93670.1 - 0.031 13.0 0.1 1.4 7.6 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3808) TPR_14 PF13428.6 ORX93670.1 - 0.041 14.7 0.1 17 6.5 0.1 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 ORX93670.1 - 0.062 14.0 0.1 20 6.1 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat DnaJ PF00226.31 ORX93672.1 - 6.1e-09 35.9 0.0 1.1e-08 35.1 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain FliT PF05400.13 ORX93672.1 - 0.1 13.4 0.6 0.18 12.6 0.6 1.5 1 0 0 1 1 1 0 Flagellar protein FliT PHO4 PF01384.20 ORX93672.1 - 0.19 10.7 0.0 0.19 10.7 0.0 1.1 1 0 0 1 1 1 0 Phosphate transporter family 3Beta_HSD PF01073.19 ORX93674.1 - 7.7e-59 199.0 0.0 1.2e-58 198.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 ORX93674.1 - 1.1e-27 97.1 0.0 1.4e-27 96.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ORX93674.1 - 5.6e-13 49.0 0.0 1.7e-09 37.6 0.0 2.0 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 ORX93674.1 - 2.9e-11 43.0 0.1 5.1e-08 32.4 0.0 2.2 1 1 1 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 ORX93674.1 - 1.5e-06 27.5 0.0 2.3e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 ORX93674.1 - 2.4e-05 24.3 0.0 3.3e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 ORX93674.1 - 5.5e-05 22.4 0.6 0.00011 21.5 0.6 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 ORX93674.1 - 0.0063 16.1 0.1 0.0092 15.6 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family Sacchrp_dh_NADP PF03435.18 ORX93674.1 - 0.022 15.0 0.2 0.038 14.3 0.2 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain KR PF08659.10 ORX93674.1 - 0.027 14.4 0.0 0.04 13.8 0.0 1.4 1 0 0 1 1 1 0 KR domain TrkA_N PF02254.18 ORX93674.1 - 0.046 14.0 0.0 0.1 12.9 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain DapB_N PF01113.20 ORX93674.1 - 0.1 12.8 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus F-box PF00646.33 ORX93675.1 - 0.035 14.0 0.1 0.061 13.2 0.1 1.4 1 0 0 1 1 1 0 F-box domain HET PF06985.11 ORX93676.1 - 4.1e-11 43.4 0.1 5.2e-11 43.1 0.1 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Pyr_redox_2 PF07992.14 ORX93678.1 - 5.5e-36 124.3 0.0 6.9e-36 124.0 0.0 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORX93678.1 - 8.5e-10 39.1 0.1 1.7e-08 34.9 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ORX93678.1 - 1.3e-05 24.6 0.0 2.2e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ORX93678.1 - 0.00029 20.8 1.5 6.9 6.6 0.0 4.1 3 1 1 4 4 4 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 ORX93678.1 - 0.0021 17.3 0.3 0.049 12.8 0.1 2.4 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 ORX93678.1 - 0.74 8.4 3.5 16 4.1 0.0 2.9 1 1 2 3 3 3 0 HI0933-like protein Fungal_trans_2 PF11951.8 ORX93679.1 - 8e-13 47.9 0.0 8.8e-13 47.8 0.0 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Arm-DNA-bind_1 PF09003.10 ORX93679.1 - 0.047 13.8 0.0 0.37 11.0 0.0 2.3 2 1 1 3 3 3 0 Bacteriophage lambda integrase, Arm DNA-binding domain MFS_1 PF07690.16 ORX93693.1 - 9.8e-15 54.3 18.6 9.8e-15 54.3 18.6 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORX93693.1 - 0.0001 21.3 2.4 0.0001 21.3 2.4 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter HLH PF00010.26 ORX93695.1 - 1e-15 57.4 0.1 3.2e-15 55.8 0.2 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Borrelia_orfX PF04160.12 ORX93696.1 - 0.47 10.5 1.7 10 6.2 0.1 2.2 2 0 0 2 2 2 0 Orf-X protein DUF1282 PF06930.12 ORX93697.1 - 0.028 14.2 1.1 0.041 13.6 1.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1282) Hydin_ADK PF17213.3 ORX93697.1 - 0.099 12.9 2.7 0.21 11.9 2.7 1.5 1 1 0 1 1 1 0 Hydin Adenylate kinase-like domain RRM_1 PF00076.22 ORX93698.1 - 1.9e-44 149.3 0.0 2.4e-21 75.3 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 ORX93698.1 - 1.5e-05 25.1 0.0 0.25 11.5 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif RRM_occluded PF16842.5 ORX93698.1 - 0.00044 20.1 0.0 0.071 13.0 0.0 2.4 2 0 0 2 2 2 1 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 ORX93698.1 - 0.0079 16.2 0.0 2.5 8.2 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 ORX93698.1 - 0.029 14.0 0.0 1.5 8.4 0.0 2.3 1 1 1 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 ORX93698.1 - 0.049 13.7 2.1 0.3 11.1 0.0 2.9 3 0 0 3 3 3 0 RNA binding motif FHA PF00498.26 ORX93716.1 - 3.1e-12 46.7 0.0 7.4e-12 45.5 0.0 1.7 1 0 0 1 1 1 1 FHA domain zf-RING_2 PF13639.6 ORX93716.1 - 3.8e-09 36.7 9.1 8.1e-09 35.7 9.1 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 ORX93716.1 - 7e-08 32.2 8.8 1.4e-07 31.2 8.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORX93716.1 - 6.2e-06 26.0 7.1 1.3e-05 25.0 7.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 ORX93716.1 - 7.9e-06 26.1 8.5 3e-05 24.2 8.5 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 ORX93716.1 - 2.2e-05 24.2 4.2 3.9e-05 23.4 4.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 ORX93716.1 - 0.061 13.1 5.9 0.15 11.9 5.9 1.6 1 0 0 1 1 1 0 RING-like zinc finger Yop-YscD_cpl PF16697.5 ORX93716.1 - 0.16 12.3 0.0 26 5.2 0.0 2.6 2 0 0 2 2 2 0 Inner membrane component of T3SS, cytoplasmic domain Prok-RING_4 PF14447.6 ORX93716.1 - 0.19 11.6 6.1 0.4 10.6 6.1 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 ORX93716.1 - 2.8 8.0 7.2 6.9 6.8 7.2 1.7 1 0 0 1 1 1 0 RING-type zinc-finger HA2 PF04408.23 ORX93717.1 - 4.2e-22 78.5 0.1 4.2e-22 78.5 0.1 3.0 3 1 0 3 3 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 ORX93717.1 - 2.3e-21 75.9 0.0 4.9e-21 74.9 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 ORX93717.1 - 1.5e-12 47.8 0.0 8e-12 45.5 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain S1 PF00575.23 ORX93717.1 - 1.1e-10 41.6 1.1 2.3e-10 40.6 1.1 1.5 1 0 0 1 1 1 1 S1 RNA binding domain DEAD PF00270.29 ORX93717.1 - 3.7e-06 26.8 1.1 1.2e-05 25.1 1.1 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 ORX93717.1 - 1.7e-05 25.1 1.7 2e-05 24.9 0.1 1.9 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 ORX93717.1 - 0.00026 20.8 0.4 0.00076 19.2 0.2 1.9 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 ORX93717.1 - 0.00038 19.6 0.0 0.00087 18.4 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.6 ORX93717.1 - 0.0083 16.5 0.2 0.019 15.3 0.2 1.6 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 ORX93717.1 - 0.028 13.7 0.0 0.058 12.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_14 PF13173.6 ORX93717.1 - 0.083 12.9 0.6 0.9 9.6 0.6 2.3 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 ORX93717.1 - 0.083 12.3 0.1 0.25 10.7 0.1 1.8 1 0 0 1 1 1 0 PhoH-like protein IstB_IS21 PF01695.17 ORX93717.1 - 0.089 12.5 0.1 14 5.4 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein Pkinase PF00069.25 ORX93754.1 - 6.2e-06 25.8 0.0 0.00023 20.6 0.0 2.5 2 1 1 3 3 3 2 Protein kinase domain DJ-1_PfpI PF01965.24 ORX93756.1 - 9.6e-12 45.0 0.0 1.2e-11 44.7 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family ABC_membrane PF00664.23 ORX93757.1 - 6e-99 331.1 45.4 2.6e-50 171.6 19.0 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 ORX93757.1 - 1.5e-67 226.4 0.0 3.7e-33 114.9 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 ORX93757.1 - 1.1e-14 54.5 6.2 5.1e-07 29.4 1.4 4.3 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 ORX93757.1 - 1.4e-07 31.1 2.3 0.017 14.9 0.0 3.2 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 ORX93757.1 - 4.4e-06 26.7 1.7 0.27 11.0 0.1 4.1 3 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 ORX93757.1 - 7.1e-06 26.3 2.5 0.057 13.7 0.0 3.8 2 2 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 ORX93757.1 - 1.6e-05 24.3 0.2 0.012 15.0 0.0 2.9 3 0 0 3 3 3 1 Zeta toxin G-alpha PF00503.20 ORX93757.1 - 3.3e-05 23.2 0.0 0.074 12.2 0.0 2.3 2 0 0 2 2 2 2 G-protein alpha subunit RsgA_GTPase PF03193.16 ORX93757.1 - 0.00016 21.7 0.0 0.57 10.1 0.0 2.8 2 0 0 2 2 2 2 RsgA GTPase AAA_25 PF13481.6 ORX93757.1 - 0.0002 21.0 0.5 0.33 10.5 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.6 ORX93757.1 - 0.00024 21.5 4.2 0.12 12.8 0.2 3.4 2 2 0 2 2 2 2 AAA ATPase domain AAA_15 PF13175.6 ORX93757.1 - 0.00039 20.2 0.0 0.81 9.3 0.0 2.6 2 1 0 2 2 2 2 AAA ATPase domain AAA_33 PF13671.6 ORX93757.1 - 0.00041 20.5 0.2 1.5 9.0 0.0 3.5 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 ORX93757.1 - 0.00043 20.0 2.7 0.09 12.5 0.0 3.4 4 0 0 4 4 4 1 AAA domain Ploopntkinase3 PF18751.1 ORX93757.1 - 0.00056 19.9 0.2 0.67 9.8 0.0 2.4 2 0 0 2 2 2 2 P-loop Nucleotide Kinase3 SbcCD_C PF13558.6 ORX93757.1 - 0.0015 18.7 1.8 2.4 8.5 0.2 3.5 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.6 ORX93757.1 - 0.0017 18.9 0.0 2.5 8.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain PRK PF00485.18 ORX93757.1 - 0.0023 17.7 0.0 0.72 9.6 0.0 2.9 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_28 PF13521.6 ORX93757.1 - 0.003 17.8 0.0 2.7 8.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 ORX93757.1 - 0.0034 17.5 0.4 0.93 9.5 0.0 3.1 2 0 0 2 2 2 1 Helicase HerA, central domain ABC_ATPase PF09818.9 ORX93757.1 - 0.0035 16.2 2.0 0.37 9.5 0.0 3.0 3 0 0 3 3 3 1 Predicted ATPase of the ABC class APS_kinase PF01583.20 ORX93757.1 - 0.004 17.1 0.1 1.2 9.1 0.0 2.6 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_24 PF13479.6 ORX93757.1 - 0.007 16.1 0.0 5.6 6.6 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 ORX93757.1 - 0.0095 15.9 0.0 6.5 6.8 0.0 3.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_23 PF13476.6 ORX93757.1 - 0.013 16.0 4.0 0.78 10.2 0.1 3.2 3 0 0 3 3 3 0 AAA domain MMR_HSR1 PF01926.23 ORX93757.1 - 0.017 15.2 0.1 10 6.2 0.0 2.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase NB-ARC PF00931.22 ORX93757.1 - 0.025 13.8 0.8 3 7.0 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain DUF2567 PF10821.8 ORX93757.1 - 0.026 14.6 0.4 0.089 12.9 0.4 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2567) AAA_17 PF13207.6 ORX93757.1 - 0.042 14.3 0.4 2 8.8 0.0 2.9 3 0 0 3 3 2 0 AAA domain AAA_7 PF12775.7 ORX93757.1 - 0.045 13.3 0.1 11 5.5 0.0 2.6 2 0 0 2 2 2 0 P-loop containing dynein motor region FtsK_SpoIIIE PF01580.18 ORX93757.1 - 0.052 12.9 0.2 7.7 5.8 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family Tex_YqgF PF16921.5 ORX93757.1 - 0.063 13.7 3.8 1.1 9.7 0.1 3.1 3 0 0 3 3 2 0 Tex protein YqgF-like domain DEAD PF00270.29 ORX93757.1 - 0.26 11.0 2.3 26 4.5 0.0 3.4 2 1 0 2 2 2 0 DEAD/DEAH box helicase Peptidase_S58 PF03576.14 ORX93758.1 - 1.7e-112 375.8 0.0 2e-112 375.6 0.0 1.0 1 0 0 1 1 1 1 Peptidase family S58 HET PF06985.11 ORX93759.1 - 3.4e-27 95.6 0.0 5.4e-27 94.9 0.0 1.3 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Glyco_transf_24 PF18404.1 ORX93759.1 - 0.11 11.8 0.0 0.14 11.5 0.0 1.1 1 0 0 1 1 1 0 Glucosyltransferase 24 DotA PF11388.8 ORX93760.1 - 0.12 12.6 0.0 0.28 11.4 0.0 1.6 1 0 0 1 1 1 0 Phagosome trafficking protein DotA HET PF06985.11 ORX93761.1 - 5.5e-24 85.2 0.0 7.5e-24 84.7 0.0 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Pheromone PF08015.11 ORX93763.1 - 2.7 9.1 5.5 0.93 10.6 0.8 2.6 2 1 0 2 2 2 0 Fungal mating-type pheromone TFR_dimer PF04253.15 ORX93765.1 - 1.1e-21 77.1 0.0 1.9e-21 76.4 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 ORX93765.1 - 1.8e-21 76.8 0.0 3.2e-21 75.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 ORX93765.1 - 3.8e-09 36.5 0.1 1.3e-08 34.8 0.1 1.9 1 0 0 1 1 1 1 PA domain CFEM PF05730.11 ORX93766.1 - 9.4e-14 51.3 6.7 1.7e-13 50.4 6.7 1.4 1 0 0 1 1 1 1 CFEM domain GST_N_2 PF13409.6 ORX93788.1 - 0.11 12.8 0.0 0.14 12.4 0.0 1.1 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain NMT1 PF09084.11 ORX93789.1 - 0.00019 21.4 0.0 0.0012 18.8 0.0 2.2 2 1 1 3 3 3 1 NMT1/THI5 like NMT1_2 PF13379.6 ORX93789.1 - 0.055 13.2 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 NMT1-like family Fungal_trans PF04082.18 ORX93790.1 - 9.9e-09 34.6 0.3 2.5e-08 33.3 0.1 1.9 2 1 0 2 2 2 1 Fungal specific transcription factor domain Sugar_tr PF00083.24 ORX93791.1 - 6.4e-05 22.0 2.1 6.4e-05 22.0 2.1 2.3 2 1 0 2 2 2 2 Sugar (and other) transporter DUF3784 PF12650.7 ORX93791.1 - 5.4 7.3 8.2 10 6.4 0.8 3.6 3 1 0 3 3 3 0 Domain of unknown function (DUF3784) HET PF06985.11 ORX93792.1 - 6.6e-14 52.5 0.2 1.9e-12 47.8 0.1 2.2 2 0 0 2 2 2 2 Heterokaryon incompatibility protein (HET) adh_short PF00106.25 ORX93793.1 - 1.9e-12 47.0 0.1 2.5e-12 46.7 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORX93793.1 - 2.5e-10 40.3 0.5 3.5e-10 39.9 0.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 ORX93793.1 - 0.00049 19.6 0.0 0.00065 19.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 ORX93793.1 - 0.0038 16.4 0.0 0.0072 15.5 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 ORX93794.1 - 5.7e-25 87.9 0.0 7.9e-25 87.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORX93794.1 - 4.7e-20 72.2 0.0 6.2e-20 71.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORX93794.1 - 5.9e-05 23.1 0.1 0.00041 20.3 0.0 2.1 2 1 0 2 2 2 1 KR domain NAD_binding_10 PF13460.6 ORX93794.1 - 0.0031 17.4 0.0 0.0041 17.0 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding Lar_N PF09861.9 ORX93794.1 - 0.0048 16.1 0.0 0.0071 15.5 0.0 1.4 1 0 0 1 1 1 1 Lactate racemase N-terminal domain Fungal_trans_2 PF11951.8 ORX93795.1 - 5.4e-26 91.3 0.0 7.6e-26 90.8 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORX93795.1 - 1.2e-10 41.3 8.0 2.3e-10 40.4 8.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pyr_redox_2 PF07992.14 ORX93796.1 - 1.4e-47 162.4 1.9 2e-47 161.8 1.9 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NIR_SIR PF01077.22 ORX93796.1 - 7.3e-20 71.1 0.0 1.4e-19 70.2 0.0 1.4 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Pyr_redox PF00070.27 ORX93796.1 - 1.4e-17 64.0 4.5 3.1e-16 59.7 1.8 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Fer2_BFD PF04324.15 ORX93796.1 - 1.9e-16 60.1 7.0 1.1e-12 48.1 5.4 2.9 2 0 0 2 2 2 2 BFD-like [2Fe-2S] binding domain Rieske PF00355.26 ORX93796.1 - 1.6e-14 53.6 0.0 3.7e-14 52.4 0.0 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 ORX93796.1 - 1.7e-13 50.4 0.0 6.6e-13 48.5 0.0 2.1 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain NIR_SIR_ferr PF03460.17 ORX93796.1 - 8e-11 41.6 0.0 1.7e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain NAD_binding_9 PF13454.6 ORX93796.1 - 0.00074 19.5 0.9 5.1 7.1 0.0 3.4 2 1 1 3 3 3 2 FAD-NAD(P)-binding Rubredoxin_C PF18267.1 ORX93796.1 - 0.0013 18.6 0.8 4.7 7.2 0.0 3.6 3 0 0 3 3 3 2 Rubredoxin NAD+ reductase C-terminal domain Pyr_redox_3 PF13738.6 ORX93796.1 - 0.0039 16.5 0.0 0.0091 15.3 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ORX93796.1 - 0.054 12.6 2.3 1.4 7.9 0.1 3.1 3 1 1 4 4 4 0 FAD binding domain NAD_binding_7 PF13241.6 ORX93796.1 - 0.06 13.8 0.2 3.2 8.3 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding Pkinase_fungal PF17667.1 ORX93797.1 - 6e-13 48.3 0.1 6.4e-13 48.3 0.1 1.0 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 ORX93817.1 - 0.0095 15.3 0.0 0.0095 15.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX93817.1 - 0.1 11.8 0.0 0.1 11.8 0.0 1.0 1 0 0 1 1 1 0 Protein tyrosine kinase DUF4834 PF16118.5 ORX93818.1 - 0.007 17.3 1.7 0.0075 17.2 1.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4834) HA2 PF04408.23 ORX93818.1 - 0.25 11.7 3.4 0.31 11.4 3.4 1.2 1 0 0 1 1 1 0 Helicase associated domain (HA2) V_ATPase_I PF01496.19 ORX93818.1 - 0.32 8.9 7.6 0.33 8.8 7.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2956 PF11169.8 ORX93818.1 - 0.53 10.5 10.7 0.65 10.2 10.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) Connexin PF00029.19 ORX93818.1 - 1.1 8.9 5.8 1 9.0 5.8 1.0 1 0 0 1 1 1 0 Connexin Presenilin PF01080.17 ORX93818.1 - 1.4 7.6 6.9 1.3 7.7 6.9 1.0 1 0 0 1 1 1 0 Presenilin UPF0242 PF06785.11 ORX93818.1 - 1.4 8.9 11.1 1.5 8.9 11.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF2828 PF11443.8 ORX93818.1 - 3.5 5.6 8.9 3.6 5.6 8.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) AAA PF00004.29 ORX93819.1 - 0.0011 19.4 0.0 0.0011 19.4 0.0 1.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Spy1 PF11357.8 ORX93819.1 - 0.16 12.2 0.1 0.18 12.1 0.1 1.1 1 0 0 1 1 1 0 Cell cycle regulatory protein Esterase_phd PF10503.9 ORX93855.1 - 2.1e-07 30.6 0.1 6.3e-06 25.8 0.0 2.3 1 1 1 2 2 2 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 ORX93855.1 - 0.00018 21.1 0.2 0.00087 18.8 0.1 1.9 1 1 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 ORX93855.1 - 0.00073 19.4 0.0 0.0011 18.9 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Esterase PF00756.20 ORX93855.1 - 0.0015 18.3 0.1 0.0025 17.5 0.1 1.4 1 1 0 1 1 1 1 Putative esterase Peptidase_S15 PF02129.18 ORX93855.1 - 0.016 14.8 0.1 0.021 14.4 0.1 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) FAD_binding_8 PF08022.12 ORX93856.1 - 0.0076 16.3 0.0 0.021 14.9 0.0 1.8 2 0 0 2 2 2 1 FAD-binding domain Spherulin4 PF12138.8 ORX93857.1 - 1.5e-65 221.2 0.4 1.7e-65 221.1 0.4 1.0 1 0 0 1 1 1 1 Spherulation-specific family 4 Nrap_D2 PF17403.2 ORX93858.1 - 0.013 15.3 0.0 0.016 15.0 0.0 1.2 1 0 0 1 1 1 0 Nrap protein PAP/OAS-like domain Pkinase PF00069.25 ORX93858.1 - 0.067 12.5 0.0 0.081 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain HpaB_N PF11794.8 ORX93859.1 - 0.058 13.0 0.0 0.084 12.5 0.0 1.1 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal APH PF01636.23 ORX93861.1 - 1.3e-14 54.7 0.1 2.3e-14 53.9 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 ORX93861.1 - 0.07 12.4 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase DUF3723 PF12520.8 ORX93862.1 - 0.0049 15.6 0.0 0.007 15.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3723) pXO2-34 PF17362.2 ORX93862.1 - 0.2 11.5 0.3 0.46 10.4 0.3 1.5 1 0 0 1 1 1 0 Family of unknown function NAD_binding_9 PF13454.6 ORX93863.1 - 0.13 12.2 0.0 0.19 11.7 0.0 1.3 1 1 0 1 1 1 0 FAD-NAD(P)-binding Exo_endo_phos PF03372.23 ORX93865.1 - 1.6e-06 27.8 0.0 2.2e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Phage_Coat_A PF05357.13 ORX93865.1 - 0.23 11.3 0.2 0.41 10.5 0.2 1.4 1 0 0 1 1 1 0 Phage Coat Protein A Oxidored_FMN PF00724.20 ORX93866.1 - 7.7e-87 291.7 0.0 3.1e-85 286.4 0.0 2.0 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family AP_endonuc_2 PF01261.24 ORX93866.1 - 0.058 12.8 0.0 7.1 6.0 0.0 2.8 2 1 1 3 3 3 0 Xylose isomerase-like TIM barrel His_biosynth PF00977.21 ORX93866.1 - 0.16 11.4 0.0 0.27 10.7 0.0 1.2 1 0 0 1 1 1 0 Histidine biosynthesis protein FAD_binding_5 PF00941.21 ORX93867.1 - 1.1e-41 142.4 0.0 1.8e-41 141.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Fer2_2 PF01799.20 ORX93867.1 - 1.3e-25 89.2 0.0 2.7e-25 88.2 0.0 1.6 1 0 0 1 1 1 1 [2Fe-2S] binding domain CO_deh_flav_C PF03450.17 ORX93867.1 - 1.9e-16 60.1 0.1 5.3e-16 58.7 0.1 1.8 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain Fer2 PF00111.27 ORX93867.1 - 3.5e-08 33.3 0.0 3.5e-08 33.3 0.0 2.9 3 0 0 3 3 3 1 2Fe-2S iron-sulfur cluster binding domain MFS_1_like PF12832.7 ORX93897.1 - 0.12 11.2 5.2 0.22 10.3 5.2 1.5 1 1 0 1 1 1 0 MFS_1 like family Coiled-coil_56 PF09813.9 ORX93898.1 - 0.022 14.8 2.1 0.037 14.1 2.1 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 56 E_Pc_C PF06752.12 ORX93898.1 - 1.7 8.7 6.6 3.1 7.9 6.6 1.3 1 0 0 1 1 1 0 Enhancer of Polycomb C-terminus PP-binding PF00550.25 ORX93899.1 - 1.2e-05 25.6 0.0 1.8e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.25 ORX93900.1 - 1.2e-15 57.5 0.0 4.7e-14 52.3 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORX93900.1 - 2.2e-09 37.2 0.0 1.5e-07 31.2 0.0 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORX93900.1 - 0.00081 19.3 0.0 0.006 16.5 0.0 1.9 2 0 0 2 2 2 1 KR domain Sugar_tr PF00083.24 ORX93901.1 - 2.1e-51 175.2 24.6 1.5e-48 165.8 24.6 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORX93901.1 - 3.7e-06 26.1 36.1 1.3e-05 24.3 31.8 2.9 1 1 1 2 2 2 2 Major Facilitator Superfamily ADH_N PF08240.12 ORX93902.1 - 4e-22 78.2 1.2 8.6e-22 77.1 1.2 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORX93902.1 - 1.3e-11 44.6 0.0 2e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 ORX93902.1 - 3.1e-06 26.8 0.1 2e-05 24.2 0.1 2.3 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus tRNA_edit PF04073.15 ORX93902.1 - 0.15 12.2 0.0 1.7 8.8 0.0 2.2 2 0 0 2 2 2 0 Aminoacyl-tRNA editing domain Pyr_redox_3 PF13738.6 ORX93902.1 - 0.17 11.1 0.1 1.3 8.2 0.1 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Transketolase_N PF00456.21 ORX93903.1 - 1.3e-35 122.9 1.0 2.1e-20 72.9 0.1 4.8 1 1 3 4 4 4 3 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 ORX93903.1 - 7.2e-31 107.2 0.1 1.2e-30 106.5 0.1 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 ORX93903.1 - 2.2e-06 27.5 0.0 6.9e-06 26.0 0.0 1.9 1 1 0 1 1 1 1 Transketolase, C-terminal domain Fungal_trans_2 PF11951.8 ORX93904.1 - 1.7e-11 43.6 0.1 2.2e-11 43.2 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.18 ORX93904.1 - 0.013 14.6 0.1 0.023 13.7 0.1 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain Zn_clus PF00172.18 ORX93906.1 - 0.0006 19.9 0.8 0.001 19.1 0.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldo_ket_red PF00248.21 ORX93907.1 - 5.7e-31 107.8 0.0 1.9e-30 106.1 0.0 1.6 1 1 0 1 1 1 1 Aldo/keto reductase family Epimerase PF01370.21 ORX93908.1 - 8.1e-11 41.8 0.1 1.5e-10 40.9 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 ORX93908.1 - 4.7e-05 23.1 0.0 8.6e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ORX93908.1 - 0.0015 18.5 0.0 0.0029 17.5 0.0 1.5 2 0 0 2 2 2 1 NAD(P)H-binding NAD_binding_4 PF07993.12 ORX93908.1 - 0.0026 17.0 0.1 0.031 13.4 0.0 2.2 1 1 1 2 2 2 1 Male sterility protein RmlD_sub_bind PF04321.17 ORX93908.1 - 0.0046 16.1 0.0 1.4 8.0 0.0 2.2 2 0 0 2 2 2 2 RmlD substrate binding domain 3Beta_HSD PF01073.19 ORX93908.1 - 0.021 13.9 0.0 0.33 9.9 0.0 2.4 3 0 0 3 3 3 0 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 ORX93908.1 - 0.048 13.1 0.0 7.4 5.9 0.0 2.3 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Semialdhyde_dh PF01118.24 ORX93908.1 - 0.11 13.0 0.0 0.21 12.1 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Y_phosphatase3 PF13350.6 ORX93924.1 - 5.5e-31 108.3 0.0 4.4e-30 105.4 0.0 1.9 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 ORX93924.1 - 0.033 13.8 0.0 0.095 12.3 0.0 1.7 2 0 0 2 2 2 0 Tyrosine phosphatase family PTPlike_phytase PF14566.6 ORX93924.1 - 0.067 13.3 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase PF00102.27 ORX93924.1 - 0.14 11.7 0.0 0.19 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Sugar_tr PF00083.24 ORX93925.1 - 3.2e-96 323.0 20.2 3.6e-96 322.8 20.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORX93925.1 - 7e-30 104.1 25.9 7e-30 104.1 25.9 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily NrsF PF06532.11 ORX93925.1 - 0.097 12.4 6.3 0.33 10.7 6.0 2.0 1 1 0 1 1 1 0 Negative regulator of sigma F MFS_1 PF07690.16 ORX93926.1 - 4.7e-26 91.5 17.7 4.7e-26 91.5 17.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORX93926.1 - 3.1e-13 49.4 0.6 6.4e-13 48.4 0.0 1.9 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 ORX93926.1 - 0.00063 18.3 0.4 0.00093 17.7 0.4 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF4051 PF13260.6 ORX93926.1 - 1.9 8.3 4.6 4.5 7.1 4.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4051) SLATT_1 PF18181.1 ORX93928.1 - 0.088 12.7 4.8 4.9 7.1 1.5 2.1 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 MFS_1 PF07690.16 ORX93929.1 - 4.1e-30 104.9 53.0 8.1e-28 97.4 33.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_holin_2_4 PF16082.5 ORX93929.1 - 3.2e-05 23.6 2.7 0.0029 17.3 0.1 3.7 3 0 0 3 3 3 1 Bacteriophage holin family, superfamily II-like Got1 PF04178.12 ORX93929.1 - 0.051 14.0 1.1 0.051 14.0 1.1 3.4 3 1 0 3 3 3 0 Got1/Sft2-like family UPF0182 PF03699.13 ORX93929.1 - 0.13 10.4 0.2 0.23 9.6 0.2 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) F-box-like_2 PF13013.6 ORX93932.1 - 0.0046 16.9 0.0 0.01 15.8 0.0 1.6 1 0 0 1 1 1 1 F-box-like domain SSXT PF05030.12 ORX93933.1 - 0.094 12.4 6.2 2.8 7.6 0.8 2.6 2 1 0 2 2 2 0 SSXT protein (N-terminal region) Prominin PF05478.11 ORX93933.1 - 0.14 10.1 4.4 0.18 9.8 4.4 1.1 1 0 0 1 1 1 0 Prominin Cor1 PF04803.12 ORX93933.1 - 1.8 8.8 7.7 0.22 11.7 1.6 2.2 1 1 1 2 2 2 0 Cor1/Xlr/Xmr conserved region SlyX PF04102.12 ORX93933.1 - 6.5 7.4 7.2 1.1 9.9 1.0 2.8 2 1 1 3 3 3 0 SlyX MFS_1 PF07690.16 ORX93934.1 - 1.3e-49 169.1 50.9 1.5e-47 162.3 50.9 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 ORX93934.1 - 2.3e-20 72.6 17.1 2.3e-20 72.6 17.1 1.6 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 ORX93934.1 - 1.4e-13 50.6 11.9 1.4e-13 50.6 11.9 2.8 3 0 0 3 3 3 2 Sugar (and other) transporter Ribonucleas_3_3 PF14622.6 ORX93935.1 - 6.3e-08 32.8 0.0 1.6e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 ORX93935.1 - 8e-06 26.4 2.3 1.5e-05 25.6 0.1 2.6 2 2 0 2 2 2 1 Ribonuclease III domain MFS_1 PF07690.16 ORX93937.1 - 1.5e-37 129.4 33.8 1.5e-37 129.4 33.8 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 ORX93937.1 - 3.9e-05 23.1 7.3 3.9e-05 23.1 7.3 1.9 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB p450 PF00067.22 ORX93938.1 - 3.3e-30 105.2 0.0 1.6e-24 86.5 0.0 3.0 1 1 1 2 2 2 2 Cytochrome P450 AAA PF00004.29 ORX93952.1 - 0.0019 18.6 0.1 0.0022 18.4 0.1 1.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RIO1 PF01163.22 ORX93954.1 - 0.0026 17.4 0.1 0.0033 17.0 0.1 1.2 1 0 0 1 1 1 1 RIO1 family Pro_dh PF01619.18 ORX93969.1 - 2.1e-56 191.6 0.0 2.5e-56 191.4 0.0 1.0 1 0 0 1 1 1 1 Proline dehydrogenase DUF3772 PF12607.8 ORX93969.1 - 0.088 12.6 1.5 0.63 9.8 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3772) Cys_Met_Meta_PP PF01053.20 ORX93970.1 - 2.5e-59 200.7 0.0 8e-59 199.1 0.0 1.8 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 ORX93970.1 - 0.00069 18.7 0.0 0.0013 17.7 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V SelA PF03841.13 ORX93970.1 - 0.028 13.4 0.0 0.04 12.9 0.0 1.2 1 0 0 1 1 1 0 L-seryl-tRNA selenium transferase DUF3323 PF11796.8 ORX93970.1 - 0.037 13.9 0.0 0.067 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function N-terminus (DUF3323) Pro_isomerase PF00160.21 ORX93971.1 - 1.9e-42 145.2 0.2 2.4e-42 144.9 0.2 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ENTH PF01417.20 ORX93972.1 - 1.5e-46 157.5 0.2 2.1e-46 157.1 0.2 1.2 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 ORX93972.1 - 0.00041 19.4 0.0 0.00056 19.0 0.0 1.1 1 0 0 1 1 1 1 ANTH domain DUF5102 PF17104.5 ORX93972.1 - 0.0077 16.3 6.9 0.017 15.2 0.9 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF5102) DUF2177 PF09945.9 ORX93973.1 - 5.5 7.1 7.7 8 6.6 7.7 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2177) IMUP PF15761.5 ORX93973.1 - 5.9 7.6 9.1 0.27 12.0 2.8 1.8 2 0 0 2 2 2 0 Immortalisation up-regulated protein DUF3328 PF11807.8 ORX93974.1 - 9e-19 68.1 0.8 2.9e-18 66.5 0.0 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF3328) DUF4040 PF13244.6 ORX93974.1 - 0.12 12.6 0.1 0.12 12.6 0.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4040) Beta-lactamase PF00144.24 ORX93975.1 - 1.7e-44 152.5 0.0 3.7e-44 151.3 0.0 1.5 2 0 0 2 2 2 1 Beta-lactamase DUF3471 PF11954.8 ORX93975.1 - 0.016 15.6 0.0 0.034 14.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3471) p450 PF00067.22 ORX93976.1 - 1.2e-55 189.1 0.0 1.6e-55 188.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 VirB7 PF17413.2 ORX93976.1 - 0.072 12.4 0.5 0.19 11.1 0.0 2.0 2 0 0 2 2 2 0 Outer membrane lipoprotein virB7 Tyrosinase PF00264.20 ORX93978.1 - 1.4e-13 51.7 0.0 1.7e-12 48.1 0.0 2.0 1 1 1 2 2 2 1 Common central domain of tyrosinase Ribosomal_L14 PF00238.19 ORX93979.1 - 2.2e-33 114.9 0.0 2.7e-33 114.7 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e HET PF06985.11 ORX93981.1 - 3.1e-17 63.3 3.8 6.9e-16 58.9 3.8 2.0 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PNMA PF14893.6 ORX93981.1 - 0.027 13.9 0.0 0.027 13.9 0.0 1.0 1 0 0 1 1 1 0 PNMA p450 PF00067.22 ORX93982.1 - 6.7e-52 176.8 0.0 8.8e-52 176.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FMO-like PF00743.19 ORX93983.1 - 2.9e-17 62.3 0.2 2.4e-16 59.3 0.2 2.1 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 ORX93983.1 - 4.3e-14 52.5 0.0 1.1e-13 51.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 ORX93983.1 - 3.9e-10 39.4 0.0 8.6e-07 28.4 0.0 3.2 2 1 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 ORX93983.1 - 8.3e-08 31.8 0.1 1.4e-06 27.8 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ORX93983.1 - 3e-07 30.4 0.0 3.2e-06 27.0 0.0 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ORX93983.1 - 5.6e-07 29.1 0.0 0.00015 21.1 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ORX93983.1 - 0.00053 20.0 0.2 0.0032 17.5 0.0 2.4 3 0 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.17 ORX93983.1 - 0.021 14.1 0.0 0.096 11.9 0.0 2.0 2 0 0 2 2 2 0 Thi4 family HI0933_like PF03486.14 ORX93983.1 - 0.22 10.2 0.0 0.36 9.5 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Tannase PF07519.11 ORX94024.1 - 3.7e-09 36.0 0.3 4.1e-09 35.9 0.3 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Cytochrome_CBB3 PF13442.6 ORX94025.1 - 0.0055 17.0 0.5 0.0093 16.3 0.5 1.4 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 ORX94025.1 - 0.01 17.0 0.1 0.013 16.6 0.1 1.2 1 0 0 1 1 1 0 Cytochrome c HeLo PF14479.6 ORX94026.1 - 1.6e-45 155.5 0.1 2.5e-45 154.8 0.1 1.3 1 0 0 1 1 1 1 Prion-inhibition and propagation Ras PF00071.22 ORX94026.1 - 2.6e-20 72.6 0.1 5.3e-20 71.6 0.1 1.5 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORX94026.1 - 6.7e-11 42.5 0.1 1.3e-10 41.5 0.1 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORX94026.1 - 0.00018 21.0 0.0 0.00037 20.0 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 ORX94026.1 - 0.063 12.7 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF1289 PF06945.13 ORX94027.1 - 0.13 12.1 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1289) Peptidase_S10 PF00450.22 ORX94028.1 - 4.5e-71 240.4 1.6 6.4e-71 239.9 1.6 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase Fungal_trans_2 PF11951.8 ORX94029.1 - 7.7e-11 41.4 0.0 7e-08 31.7 0.0 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 ORX94029.1 - 6e-07 29.5 7.0 1.1e-06 28.7 7.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.22 ORX94030.1 - 2.9e-52 178.0 0.0 3.8e-52 177.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Cnn_1N PF07989.11 ORX94032.1 - 0.13 12.4 0.1 0.21 11.8 0.1 1.3 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 Gly_transf_sug PF04488.15 ORX94067.1 - 5.1e-07 30.2 0.1 2.5e-06 28.0 0.0 2.1 2 1 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 ORX94067.1 - 0.0076 15.6 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 TcdA/TcdB catalytic glycosyltransferase domain DUF4672 PF15716.5 ORX94069.1 - 0.0065 16.1 0.1 0.035 13.8 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4672) DUF3638 PF12340.8 ORX94071.1 - 8.6e-87 290.2 1.0 1.7e-86 289.2 1.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.8 ORX94071.1 - 7.5e-16 57.2 0.1 1.5e-15 56.3 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) MFS_1 PF07690.16 ORX94073.1 - 1.9e-35 122.4 27.9 1.9e-35 122.4 27.9 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORX94073.1 - 1.9e-13 50.1 6.0 1.9e-13 50.1 6.0 1.9 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 ORX94073.1 - 1.5e-08 33.6 3.4 1.5e-08 33.6 3.4 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) p450 PF00067.22 ORX94074.1 - 9.2e-58 196.1 0.0 1.9e-57 195.1 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 Ank_3 PF13606.6 ORX94100.1 - 2.9e-11 42.5 0.1 0.19 12.4 0.0 6.5 6 0 0 6 6 6 2 Ankyrin repeat Ank_4 PF13637.6 ORX94100.1 - 6.5e-10 39.3 0.1 0.003 18.1 0.0 6.2 4 2 3 7 7 7 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 ORX94100.1 - 1.4e-09 38.0 0.2 0.021 15.2 0.0 6.2 3 2 3 6 6 6 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 ORX94100.1 - 6.3e-08 33.1 0.0 4.2e-06 27.3 0.0 2.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 ORX94100.1 - 0.0047 17.3 0.0 7.2 7.2 0.0 3.9 3 1 1 4 4 4 1 Ankyrin repeat Shigella_OspC PF06128.11 ORX94100.1 - 0.045 13.5 0.0 3.5 7.3 0.0 2.1 2 0 0 2 2 2 0 Shigella flexneri OspC protein Epimerase PF01370.21 ORX94102.1 - 1.3e-10 41.1 0.0 2e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 ORX94102.1 - 8.1e-07 28.3 0.0 1.7e-06 27.3 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 ORX94102.1 - 1.4e-06 28.4 0.0 7.9e-06 25.9 0.0 2.2 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 ORX94102.1 - 0.00012 21.7 0.0 0.0002 21.0 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.25 ORX94102.1 - 0.00024 20.6 0.0 0.022 14.2 0.0 2.4 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_4 PF07993.12 ORX94102.1 - 0.00046 19.4 0.0 0.0011 18.2 0.0 1.6 1 0 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 ORX94102.1 - 0.018 14.4 0.0 0.028 13.8 0.0 1.4 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase KR PF08659.10 ORX94102.1 - 0.064 13.2 0.0 0.14 12.1 0.0 1.5 1 1 0 1 1 1 0 KR domain Ammonium_transp PF00909.21 ORX94107.1 - 6.3e-75 252.3 25.1 3.6e-74 249.8 25.1 2.1 1 1 0 1 1 1 1 Ammonium Transporter Family DMA PF03474.14 ORX94107.1 - 0.15 11.7 0.1 0.32 10.6 0.1 1.5 1 0 0 1 1 1 0 DMRTA motif DUF3188 PF11384.8 ORX94107.1 - 0.22 11.3 1.0 19 5.1 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3188) SpoV PF08183.11 ORX94107.1 - 0.58 10.2 6.9 1.4 8.9 1.0 3.3 3 0 0 3 3 3 0 Stage V sporulation protein family MtN3_slv PF03083.16 ORX94107.1 - 1.7 8.7 7.0 2.7 8.1 0.9 3.4 3 0 0 3 3 3 0 Sugar efflux transporter for intercellular exchange RsgA_GTPase PF03193.16 ORX94108.1 - 2.6e-05 24.2 0.0 0.028 14.3 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 ORX94108.1 - 2.6e-05 24.2 0.0 4.5e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 ORX94108.1 - 0.0059 16.9 0.0 0.085 13.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 ORX94108.1 - 0.012 14.8 0.0 0.021 14.0 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain ATP_bind_1 PF03029.17 ORX94108.1 - 0.014 15.2 0.2 5.1 6.8 0.1 2.5 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein ABC_tran PF00005.27 ORX94108.1 - 0.017 15.6 0.0 0.036 14.6 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 ORX94108.1 - 0.018 14.8 0.0 0.022 14.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 ORX94108.1 - 0.02 14.8 0.2 0.086 12.7 0.1 2.0 2 0 0 2 2 2 0 NACHT domain AAA_16 PF13191.6 ORX94108.1 - 0.024 15.0 0.4 0.23 11.8 0.0 2.6 2 1 1 3 3 3 0 AAA ATPase domain FANC_SAP PF18081.1 ORX94108.1 - 0.035 14.3 0.3 0.14 12.4 0.0 2.2 2 0 0 2 2 1 0 Fanconi anemia-associated nuclease SAP domain GTP_EFTU PF00009.27 ORX94108.1 - 0.038 13.5 0.1 0.45 10.0 0.1 2.0 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain Roc PF08477.13 ORX94108.1 - 0.099 12.9 0.0 0.26 11.5 0.0 1.8 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_18 PF13238.6 ORX94108.1 - 0.1 13.2 0.0 0.25 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 ORX94108.1 - 0.14 11.9 0.0 0.31 10.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Ras PF00071.22 ORX94108.1 - 0.18 11.4 0.1 0.77 9.3 0.1 2.0 1 1 0 1 1 1 0 Ras family DUF4360 PF14273.6 ORX94111.1 - 0.0042 17.0 0.4 0.0079 16.1 0.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Glycophorin_A PF01102.18 ORX94111.1 - 0.067 13.4 0.1 0.2 11.9 0.1 1.7 1 0 0 1 1 1 0 Glycophorin A DUF202 PF02656.15 ORX94111.1 - 0.26 11.7 3.0 0.51 10.8 0.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF202) DUF676 PF05057.14 ORX94139.1 - 0.0037 16.8 0.0 0.0052 16.3 0.0 1.1 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 ORX94139.1 - 0.037 13.8 0.2 0.13 11.9 0.0 1.8 2 0 0 2 2 2 0 PGAP1-like protein LIP PF03583.14 ORX94139.1 - 0.037 13.3 0.0 0.052 12.9 0.0 1.1 1 0 0 1 1 1 0 Secretory lipase DUF2278 PF10042.9 ORX94140.1 - 3.5e-73 246.0 0.0 4.5e-73 245.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2278) LTD PF00932.19 ORX94140.1 - 2.4e-10 40.8 0.1 5.5e-10 39.6 0.1 1.6 1 0 0 1 1 1 1 Lamin Tail Domain DUF4734 PF15881.5 ORX94140.1 - 0.18 12.0 0.0 0.38 11.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4734) ASXH PF13919.6 ORX94142.1 - 9.2e-13 48.4 11.8 9.8e-10 38.6 0.7 2.1 1 1 1 2 2 2 2 Asx homology domain Glyco_hydro_61 PF03443.14 ORX94143.1 - 3.2e-32 112.2 0.0 3.9e-32 111.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 SGBP_B_XBD PF18329.1 ORX94143.1 - 0.012 15.6 0.5 0.16 11.9 0.0 2.1 1 1 1 2 2 2 0 Surface glycan-binding protein B xyloglucan binding domain DUF1281_C PF18406.1 ORX94143.1 - 0.022 14.5 0.1 3.8 7.3 0.0 3.2 3 0 0 3 3 3 0 Ferredoxin-like domain in Api92-like protein EMP70 PF02990.16 ORX94144.1 - 0.054 12.2 6.1 0.072 11.8 6.1 1.1 1 0 0 1 1 1 0 Endomembrane protein 70 adh_short_C2 PF13561.6 ORX94145.1 - 6.2e-27 94.7 0.0 6.2e-17 61.9 0.1 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORX94145.1 - 5.9e-25 87.9 2.9 1.1e-11 44.5 1.5 2.1 1 1 1 2 2 2 2 short chain dehydrogenase KR PF08659.10 ORX94145.1 - 1e-06 28.8 1.5 3.3e-06 27.1 0.0 2.0 1 1 1 2 2 2 1 KR domain GDP_Man_Dehyd PF16363.5 ORX94145.1 - 0.012 15.0 0.4 0.018 14.5 0.0 1.4 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 ORX94145.1 - 0.059 12.8 0.2 0.24 10.8 0.1 1.9 1 1 1 2 2 2 0 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 ORX94145.1 - 0.12 11.4 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family p450 PF00067.22 ORX94170.1 - 8.3e-51 173.2 0.0 9.6e-51 173.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 EthD PF07110.11 ORX94172.1 - 2.2e-19 70.4 0.1 2.7e-19 70.1 0.1 1.1 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 ORX94172.1 - 7.9e-08 32.8 0.1 2.5e-07 31.2 0.1 1.7 1 1 0 1 1 1 1 Methylmuconolactone methyl-isomerase UbiA PF01040.18 ORX94173.1 - 1.2e-17 64.1 10.2 1.3e-17 64.0 9.7 1.4 1 1 0 1 1 1 1 UbiA prenyltransferase family SKG6 PF08693.10 ORX94174.1 - 0.076 12.4 0.3 0.18 11.2 0.3 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Amidase PF01425.21 ORX94204.1 - 9.6e-34 117.1 0.4 1.4e-33 116.6 0.4 1.1 1 0 0 1 1 1 1 Amidase DUF2231 PF09990.9 ORX94205.1 - 9.9e-09 35.6 1.3 1.1e-08 35.4 0.4 1.5 2 0 0 2 2 2 1 Predicted membrane protein (DUF2231) CorA PF01544.18 ORX94206.1 - 6.2e-14 52.0 5.7 8.3e-14 51.6 3.5 2.1 2 1 0 2 2 2 1 CorA-like Mg2+ transporter protein LemA PF04011.12 ORX94207.1 - 0.069 13.0 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 LemA family DUF3926 PF13080.6 ORX94207.1 - 0.12 12.4 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3926) DUF2083 PF09856.9 ORX94207.1 - 3.1 7.6 6.7 23 4.8 0.3 3.0 3 0 0 3 3 3 0 Predicted transcriptional regulator (DUF2083) CDH-cyt PF16010.5 ORX94208.1 - 7.7e-51 172.3 7.2 9e-51 172.1 7.2 1.0 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase OppC_N PF12911.7 ORX94210.1 - 1.3 9.1 0.0 1.3 9.1 0.0 2.8 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C SNF2_N PF00176.23 ORX94212.1 - 2.1e-73 247.0 0.0 3.8e-73 246.2 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 ORX94212.1 - 5.8e-42 142.3 1.8 5.8e-42 142.3 1.8 2.7 2 0 0 2 2 2 1 SLIDE HAND PF09110.11 ORX94212.1 - 2e-35 121.9 1.2 2e-35 121.9 1.2 3.3 3 0 0 3 3 2 1 HAND Helicase_C PF00271.31 ORX94212.1 - 1.1e-18 67.6 0.5 2.5e-17 63.2 0.0 3.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORX94212.1 - 8.9e-10 38.8 0.5 1.2e-08 35.1 0.0 3.0 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 ORX94212.1 - 9.7e-06 24.9 0.1 4.2e-05 22.9 0.0 2.1 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 Myb_DNA-binding PF00249.31 ORX94212.1 - 0.00069 19.8 0.1 2.2 8.5 0.0 3.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain ERCC3_RAD25_C PF16203.5 ORX94212.1 - 0.00085 18.6 0.3 0.0019 17.4 0.3 1.6 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase DEAD PF00270.29 ORX94212.1 - 0.0012 18.6 0.0 0.0035 17.1 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 ORX94212.1 - 0.0023 17.6 0.0 0.0089 15.7 0.0 2.1 2 0 0 2 2 2 1 SWI2/SNF2 ATPase DEAD_2 PF06733.15 ORX94212.1 - 0.01 15.5 0.0 0.022 14.4 0.0 1.5 1 0 0 1 1 1 0 DEAD_2 DUF1086 PF06461.11 ORX94212.1 - 0.047 13.6 0.1 0.11 12.3 0.1 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1086) AAA_14 PF13173.6 ORX94212.1 - 0.059 13.4 0.0 0.23 11.5 0.0 2.0 1 0 0 1 1 1 0 AAA domain ArsA_ATPase PF02374.15 ORX94213.1 - 7e-117 390.0 0.1 8e-117 389.8 0.1 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.6 ORX94213.1 - 1.5e-14 54.3 0.3 1.7e-12 47.6 0.0 2.6 2 1 0 2 2 2 1 AAA domain CbiA PF01656.23 ORX94213.1 - 4.6e-13 49.4 0.0 9.4e-13 48.3 0.0 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 ORX94213.1 - 7.9e-08 32.1 0.7 6.6e-05 22.5 0.0 2.6 3 0 0 3 3 3 2 NUBPL iron-transfer P-loop NTPase SRP54 PF00448.22 ORX94213.1 - 8.3e-07 28.8 0.2 0.0002 21.1 0.0 2.7 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain Fer4_NifH PF00142.18 ORX94213.1 - 5.6e-06 26.0 0.0 1.3e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family CBP_BcsQ PF06564.12 ORX94213.1 - 9.3e-06 25.3 0.0 3.2e-05 23.5 0.0 1.8 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsQ PhoH PF02562.16 ORX94213.1 - 0.064 12.7 0.0 0.19 11.2 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein Zeta_toxin PF06414.12 ORX94213.1 - 0.066 12.5 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.6 ORX94213.1 - 0.081 13.5 0.2 0.25 11.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 ORX94213.1 - 0.084 13.2 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain VirC1 PF07015.11 ORX94213.1 - 0.11 11.8 0.1 0.82 8.9 0.0 2.1 2 0 0 2 2 2 0 VirC1 protein NB-ARC PF00931.22 ORX94213.1 - 0.11 11.7 0.1 0.24 10.6 0.1 1.6 1 0 0 1 1 1 0 NB-ARC domain AAA_25 PF13481.6 ORX94213.1 - 0.15 11.6 0.0 0.67 9.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain Lipase_3 PF01764.25 ORX94214.1 - 1.2e-33 116.0 0.0 1.7e-33 115.5 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Lipase3_N PF03893.16 ORX94214.1 - 8.9e-06 25.7 0.0 1.6e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Lipase 3 N-terminal region Hydrolase_4 PF12146.8 ORX94214.1 - 0.00012 21.4 0.0 0.00018 20.8 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_8 PF06259.12 ORX94214.1 - 0.00035 20.2 0.0 0.00067 19.3 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase Cutinase PF01083.22 ORX94214.1 - 0.0067 16.4 0.0 0.013 15.5 0.0 1.4 1 0 0 1 1 1 1 Cutinase Abhydrolase_6 PF12697.7 ORX94214.1 - 0.0083 16.7 0.0 0.012 16.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.14 ORX94214.1 - 0.015 14.8 0.0 0.025 14.1 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) DUF2974 PF11187.8 ORX94214.1 - 0.016 14.8 0.0 0.031 13.8 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_5 PF12695.7 ORX94214.1 - 0.085 12.6 0.1 0.28 10.9 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ORX94214.1 - 0.1 12.2 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Aldolase_II PF00596.21 ORX94216.1 - 2e-29 102.8 0.1 2.9e-29 102.3 0.1 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain FAD_binding_3 PF01494.19 ORX94217.1 - 1.1e-16 61.1 0.0 7.2e-11 41.9 0.0 2.8 2 1 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.6 ORX94217.1 - 8.6e-07 28.5 0.0 8.7e-05 21.9 0.0 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 ORX94217.1 - 4.8e-05 22.6 0.2 0.00011 21.4 0.0 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 ORX94217.1 - 9.6e-05 22.5 0.0 0.00024 21.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ORX94217.1 - 0.00017 21.0 0.0 0.0018 17.5 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ORX94217.1 - 0.00028 20.1 0.0 0.00049 19.3 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 ORX94217.1 - 0.072 11.8 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein DAO PF01266.24 ORX94217.1 - 0.073 12.6 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 ORX94217.1 - 0.084 13.4 0.0 0.83 10.3 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 ORX94217.1 - 0.11 12.8 0.0 0.4 11.0 0.0 1.9 2 0 0 2 2 2 0 TrkA-N domain DUF4350 PF14258.6 ORX94218.1 - 0.0089 16.4 4.7 19 5.8 0.0 5.1 6 0 0 6 6 6 1 Domain of unknown function (DUF4350) DUF3197 PF11432.8 ORX94218.1 - 0.013 15.4 0.0 0.51 10.2 0.0 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3197) AIM5 PF17050.5 ORX94218.1 - 0.6 11.0 5.1 2e+02 2.9 0.0 5.7 5 0 0 5 5 5 0 Altered inheritance of mitochondria 5 F-box-like PF12937.7 ORX94219.1 - 0.012 15.4 0.0 0.083 12.8 0.0 2.3 2 0 0 2 2 2 0 F-box-like F-box PF00646.33 ORX94219.1 - 0.072 13.0 0.0 0.26 11.2 0.0 2.0 1 0 0 1 1 1 0 F-box domain Peptidase_M20 PF01546.28 ORX94220.1 - 4.6e-33 114.7 0.0 8.3e-33 113.8 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 ORX94220.1 - 2.1e-11 43.7 0.0 3.9e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain zf-Mss51 PF13824.6 ORX94221.1 - 0.024 14.8 0.2 0.024 14.7 0.2 1.1 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 RuBisCO_small PF00101.20 ORX94221.1 - 0.04 13.9 0.2 0.048 13.7 0.2 1.1 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase, small chain zf-C2H2_7 PF15269.6 ORX94221.1 - 0.073 13.2 0.1 0.074 13.1 0.1 1.2 1 0 0 1 1 1 0 Zinc-finger RGS PF00615.19 ORX94222.1 - 0.016 15.5 0.2 0.023 15.0 0.2 1.2 1 0 0 1 1 1 0 Regulator of G protein signaling domain SNF2_N PF00176.23 ORX94255.1 - 2e-54 184.6 0.1 4.6e-54 183.5 0.1 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.24 ORX94255.1 - 2.8e-24 84.8 0.9 2.2e-14 53.1 0.0 2.9 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.31 ORX94255.1 - 1.5e-18 67.1 0.0 4.8e-18 65.5 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4208 PF13907.6 ORX94255.1 - 2e-16 60.2 0.0 9.4e-16 58.0 0.0 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4208) Cdh1_DBD_1 PF18196.1 ORX94255.1 - 4.8e-06 26.9 0.8 4.8e-06 26.9 0.8 5.7 5 1 1 6 6 6 2 Chromodomain helicase DNA-binding domain 1 ResIII PF04851.15 ORX94255.1 - 4.3e-05 23.6 0.0 4.3e-05 23.6 0.0 3.0 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit CHDCT2 PF08074.11 ORX94255.1 - 0.00092 19.4 6.3 0.0017 18.6 0.0 3.3 3 0 0 3 3 3 1 CHDCT2 (NUC038) domain SLIDE PF09111.10 ORX94255.1 - 0.0046 17.0 0.0 0.059 13.4 0.0 3.0 1 0 0 1 1 1 1 SLIDE Baculo_PEP_N PF04512.12 ORX94255.1 - 0.12 12.7 0.1 0.32 11.3 0.1 1.7 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, N terminus Metallophos PF00149.28 ORX94256.1 - 2.6e-13 50.9 1.5 4.6e-13 50.1 1.5 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Baculo_F PF12259.8 ORX94256.1 - 0.25 9.8 1.4 0.37 9.3 1.4 1.2 1 0 0 1 1 1 0 Baculovirus F protein Zn_clus PF00172.18 ORX94257.1 - 3.1e-10 40.0 14.2 5.3e-10 39.3 14.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LEA_3 PF03242.13 ORX94257.1 - 0.23 12.2 0.4 3.1 8.6 0.1 2.3 2 1 0 2 2 2 0 Late embryogenesis abundant protein ANAPC5 PF12862.7 ORX94258.1 - 0.032 14.3 0.1 0.044 13.9 0.1 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 5 adh_short PF00106.25 ORX94259.1 - 0.00047 19.7 1.0 0.0046 16.4 1.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORX94259.1 - 0.0015 18.2 0.6 0.0026 17.3 0.6 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Xan_ur_permease PF00860.20 ORX94260.1 - 2.6e-29 102.1 26.4 2e-28 99.2 26.0 2.4 2 1 0 2 2 2 1 Permease family MFS_MOT1 PF16983.5 ORX94260.1 - 0.00066 20.1 3.7 0.00066 20.1 3.7 3.3 3 0 0 3 3 3 1 Molybdate transporter of MFS superfamily DUF2834 PF11196.8 ORX94260.1 - 0.037 14.4 2.2 0.18 12.2 2.2 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2834) Pox_A32 PF04665.12 ORX94260.1 - 0.087 12.3 0.8 0.15 11.5 0.8 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein DUF3488 PF11992.8 ORX94260.1 - 1.4 7.8 3.6 3 6.7 3.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3488) Methyltransf_11 PF08241.12 ORX94261.1 - 0.00056 20.5 0.0 0.0011 19.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORX94261.1 - 0.0021 18.7 0.0 0.0042 17.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Cdc6_C PF09079.11 ORX94261.1 - 0.13 12.3 0.0 0.65 10.0 0.0 2.1 2 0 0 2 2 2 0 CDC6, C terminal winged helix domain AhpC-TSA_2 PF13911.6 ORX94262.1 - 2.4e-06 27.6 0.0 4.1e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 ORX94262.1 - 0.00015 21.6 0.0 0.00024 21.0 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Fungal_trans_2 PF11951.8 ORX94263.1 - 4.9e-15 55.2 0.7 6.8e-15 54.8 0.7 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORX94263.1 - 1.9e-08 34.3 6.9 3e-08 33.6 6.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DHO_dh PF01180.21 ORX94264.1 - 2.6e-20 72.8 0.4 5.3e-11 42.3 0.5 2.1 2 0 0 2 2 2 2 Dihydroorotate dehydrogenase NMO PF03060.15 ORX94264.1 - 2.4 7.4 5.4 3.5 6.9 5.4 1.1 1 0 0 1 1 1 0 Nitronate monooxygenase PAS_9 PF13426.7 ORX94265.1 - 2.1e-16 60.1 0.0 4.7e-15 55.7 0.0 2.8 3 0 0 3 3 3 1 PAS domain PAS PF00989.25 ORX94265.1 - 2.7e-06 27.3 0.0 8.8e-06 25.7 0.0 1.9 1 0 0 1 1 1 1 PAS fold Use1 PF09753.9 ORX94267.1 - 0.083 12.6 0.7 0.12 12.1 0.5 1.4 1 1 0 1 1 1 0 Membrane fusion protein Use1 TRAM_LAG1_CLN8 PF03798.16 ORX94268.1 - 1.9e-42 145.3 4.6 5.5e-41 140.5 4.6 2.2 1 1 0 1 1 1 1 TLC domain DUF2108 PF09881.9 ORX94268.1 - 0.059 13.3 0.1 0.13 12.2 0.1 1.6 1 0 0 1 1 1 0 Predicted membrane protein (DUF2108) RRM_1 PF00076.22 ORX94269.1 - 1.6e-12 47.0 0.5 2.4e-06 27.2 0.0 3.1 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 ORX94269.1 - 0.0049 16.9 0.0 0.0098 16.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif DUF4336 PF14234.6 ORX94282.1 - 2.9e-18 66.1 0.2 5.7e-13 48.7 0.1 2.7 2 1 0 2 2 2 2 Domain of unknown function (DUF4336) RNase_PH PF01138.21 ORX94283.1 - 3.5e-21 76.1 0.0 7.1e-21 75.1 0.0 1.5 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 ORX94283.1 - 3.7e-10 39.7 0.0 6.5e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Cwf_Cwc_15 PF04889.12 ORX94284.1 - 7.5e-79 264.9 25.7 8.7e-79 264.7 25.7 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein IMUP PF15761.5 ORX94284.1 - 0.025 15.3 8.7 0.025 15.3 8.7 1.7 2 0 0 2 2 2 0 Immortalisation up-regulated protein SR-25 PF10500.9 ORX94284.1 - 0.36 10.4 18.1 0.13 11.9 15.6 1.4 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein PA26 PF04636.13 ORX94284.1 - 1.6 7.5 7.1 1.9 7.3 7.1 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Hid1 PF12722.7 ORX94284.1 - 6.7 4.7 10.8 7.4 4.6 10.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein AChE_tetra PF08674.10 ORX94287.1 - 0.01 15.5 0.8 0.019 14.6 0.8 1.4 1 0 0 1 1 1 0 Acetylcholinesterase tetramerisation domain zf-CCHC PF00098.23 ORX94289.1 - 5.4e-12 45.2 23.4 4.2e-05 23.4 3.8 3.2 3 0 0 3 3 3 3 Zinc knuckle zf-CCHC_4 PF14392.6 ORX94289.1 - 1.2e-05 24.9 13.8 0.0024 17.5 0.3 3.0 3 0 0 3 3 3 3 Zinc knuckle zf-CCHC_3 PF13917.6 ORX94289.1 - 3e-05 23.9 8.5 0.22 11.5 1.3 3.1 1 1 2 3 3 3 3 Zinc knuckle zf-CCHC_5 PF14787.6 ORX94289.1 - 0.0008 19.1 2.9 0.0008 19.1 2.9 2.9 2 1 1 3 3 3 1 GAG-polyprotein viral zinc-finger zf-CCHC_2 PF13696.6 ORX94289.1 - 0.025 14.4 4.6 0.025 14.4 4.6 3.4 3 0 0 3 3 3 0 Zinc knuckle CLIP1_ZNF PF16641.5 ORX94289.1 - 0.18 11.7 0.9 0.18 11.7 0.9 3.2 3 0 0 3 3 3 0 CLIP1 zinc knuckle NUDIX PF00293.28 ORX94290.1 - 0.00033 20.7 0.3 0.0012 18.8 0.1 2.1 2 1 0 2 2 2 1 NUDIX domain zf-C3HC4_3 PF13920.6 ORX94291.1 - 3.6e-11 42.7 10.1 3.6e-11 42.7 10.1 2.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 ORX94291.1 - 1.1e-05 25.2 6.8 4.5e-05 23.2 6.8 2.1 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 ORX94291.1 - 0.0029 17.5 8.2 0.0029 17.5 8.2 2.4 2 0 0 2 2 2 1 zinc-RING finger domain Tmemb_170 PF10190.9 ORX94293.1 - 2.1e-21 76.3 11.4 2.4e-21 76.1 11.4 1.0 1 0 0 1 1 1 1 Putative transmembrane protein 170 GTP_EFTU_D4 PF14578.6 ORX94294.1 - 0.16 11.9 0.1 1.8 8.6 0.0 2.1 1 1 1 2 2 2 0 Elongation factor Tu domain 4 FRB_dom PF08771.11 ORX94294.1 - 0.17 12.3 0.1 20 5.7 0.0 2.2 1 1 1 2 2 2 0 FKBP12-rapamycin binding domain NIF PF03031.18 ORX94296.1 - 6.6e-54 181.9 0.1 8.8e-54 181.5 0.1 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Kinesin PF00225.23 ORX94298.1 - 6.9e-104 347.4 0.4 6.9e-104 347.4 0.4 1.7 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 ORX94298.1 - 8.8e-59 197.7 0.0 8.8e-59 197.7 0.0 2.0 2 0 0 2 2 2 1 Microtubule binding AAA_16 PF13191.6 ORX94298.1 - 0.0029 18.0 3.5 0.0029 18.0 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain RuBisCO_large PF00016.20 ORX94298.1 - 0.0072 15.5 0.1 0.013 14.7 0.1 1.3 1 0 0 1 1 1 1 Ribulose bisphosphate carboxylase large chain, catalytic domain AAA_24 PF13479.6 ORX94298.1 - 0.032 14.0 6.5 2.6 7.7 0.0 2.9 2 1 1 3 3 3 0 AAA domain AAA_22 PF13401.6 ORX94298.1 - 1.1 9.6 5.6 0.42 10.9 0.2 2.7 2 2 0 2 2 2 0 AAA domain Metallophos PF00149.28 ORX94299.1 - 5.1e-12 46.7 0.1 1.1e-11 45.6 0.0 1.5 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 ORX94299.1 - 1.7e-05 25.1 0.1 4.6e-05 23.7 0.0 1.7 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain Ras PF00071.22 ORX94300.1 - 5.6e-26 91.1 0.0 8.5e-26 90.5 0.0 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORX94300.1 - 0.00022 21.4 0.0 0.0011 19.1 0.0 2.2 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 ORX94300.1 - 0.00087 19.2 0.0 0.99 9.3 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase PduV-EutP PF10662.9 ORX94300.1 - 0.0029 17.3 0.0 1 9.1 0.0 2.7 3 0 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.6 ORX94300.1 - 0.0048 16.6 0.0 0.0058 16.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain GTP_EFTU PF00009.27 ORX94300.1 - 0.032 13.8 0.1 3.8 7.0 0.1 2.3 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 ORX94300.1 - 0.037 14.3 0.0 0.1 12.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 ORX94300.1 - 0.041 14.3 0.0 0.096 13.1 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain MMR_HSR1 PF01926.23 ORX94300.1 - 0.044 13.9 0.0 0.085 12.9 0.0 1.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase Arf PF00025.21 ORX94300.1 - 0.12 11.8 0.1 1.1 8.7 0.1 2.1 1 1 0 1 1 1 0 ADP-ribosylation factor family AAA_7 PF12775.7 ORX94300.1 - 0.18 11.3 0.0 0.29 10.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region But2 PF09792.9 ORX94301.1 - 1.7e-07 31.7 0.3 3.9e-07 30.5 0.3 1.5 1 1 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain DUF3431 PF11913.8 ORX94325.1 - 2.4e-42 145.1 0.0 2.8e-42 144.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) KR PF08659.10 ORX94326.1 - 5e-23 81.9 0.0 9.7e-23 81.0 0.0 1.5 2 0 0 2 2 2 1 KR domain DUF2157 PF09925.9 ORX94327.1 - 0.007 16.2 4.6 0.007 16.2 4.6 1.9 2 1 0 2 2 2 1 Predicted membrane protein (DUF2157) SCAMP PF04144.13 ORX94327.1 - 0.93 9.8 11.9 0.15 12.3 7.1 2.0 1 1 0 2 2 2 0 SCAMP family DUF4418 PF14387.6 ORX94327.1 - 0.93 9.7 7.1 2.4 8.4 5.5 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4418) UPF0542 PF15086.6 ORX94327.1 - 3.2 7.8 11.1 0.84 9.6 1.8 3.2 2 1 1 3 3 3 0 Uncharacterised protein family UPF0542 ATG11 PF10377.9 ORX94328.1 - 0.14 12.2 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 Autophagy-related protein 11 MFS_1 PF07690.16 ORX94329.1 - 4.6e-38 131.0 43.8 3.4e-36 124.9 44.9 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 ORX94329.1 - 8.3e-14 50.9 13.2 9.3e-14 50.7 13.2 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 ORX94329.1 - 1.5e-06 27.4 16.1 1.5e-06 27.4 16.1 1.8 2 0 0 2 2 2 1 Sugar (and other) transporter p450 PF00067.22 ORX94330.1 - 7.7e-51 173.3 0.0 9.6e-51 172.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 UDPGT PF00201.18 ORX94331.1 - 4.9e-25 88.3 0.0 6.2e-25 88.0 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 ORX94331.1 - 0.0062 16.5 0.0 0.011 15.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain ketoacyl-synt PF00109.26 ORX94332.1 - 2.8e-70 236.8 0.0 1.7e-69 234.2 0.0 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 ORX94332.1 - 1.3e-62 210.9 0.5 2.6e-61 206.7 0.3 2.7 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.21 ORX94332.1 - 2e-55 188.5 0.0 3.2e-55 187.9 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 ORX94332.1 - 7.5e-47 160.0 0.0 1.8e-46 158.7 0.0 1.7 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 ORX94332.1 - 4.1e-38 130.0 0.0 2.2e-37 127.7 0.0 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 ORX94332.1 - 4.1e-16 59.4 0.1 2.9e-15 56.7 0.1 2.6 1 1 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_12 PF08242.12 ORX94332.1 - 6.3e-16 58.9 0.0 6.3e-16 58.9 0.0 3.0 2 0 0 2 2 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.6 ORX94332.1 - 8.3e-16 59.3 0.1 1.6e-14 55.1 0.0 3.1 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 ORX94332.1 - 6e-14 52.1 0.0 3.2e-13 49.8 0.0 2.4 2 0 0 2 2 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 ORX94332.1 - 2e-13 50.3 0.2 9.2e-12 44.8 0.0 2.8 2 0 0 2 2 2 1 short chain dehydrogenase Methyltransf_23 PF13489.6 ORX94332.1 - 9.4e-12 45.1 0.6 3.2e-11 43.4 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORX94332.1 - 8.5e-10 39.2 0.1 4.9e-08 33.6 0.0 3.8 3 0 0 3 3 2 1 Methyltransferase domain adh_short_C2 PF13561.6 ORX94332.1 - 4.7e-09 36.1 0.0 4.7e-09 36.1 0.0 2.6 3 0 0 3 3 3 1 Enoyl-(Acyl carrier protein) reductase Methyltransf_31 PF13847.6 ORX94332.1 - 6.8e-08 32.4 1.3 1.9e-07 31.0 0.0 2.5 2 0 0 2 2 1 1 Methyltransferase domain PP-binding PF00550.25 ORX94332.1 - 2.4e-06 27.8 0.1 7.7e-06 26.2 0.1 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.23 ORX94332.1 - 3.1e-06 26.8 0.3 8.2e-05 22.1 0.0 2.7 2 0 0 2 2 2 1 Thiolase, N-terminal domain Methyltransf_11 PF08241.12 ORX94332.1 - 9.3e-06 26.2 0.1 0.00014 22.5 0.0 3.0 2 0 0 2 2 2 1 Methyltransferase domain ADH_N PF08240.12 ORX94332.1 - 2.9e-05 23.9 0.1 8.2e-05 22.4 0.1 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_16 PF10294.9 ORX94332.1 - 0.0028 17.4 0.0 0.0091 15.7 0.0 1.8 1 1 0 1 1 1 1 Lysine methyltransferase CoA_trans PF01144.23 ORX94332.1 - 0.012 15.0 0.0 4.8 6.5 0.0 2.4 2 0 0 2 2 2 0 Coenzyme A transferase Ubie_methyltran PF01209.18 ORX94332.1 - 0.012 14.9 0.0 0.029 13.7 0.0 1.6 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family DUF2052 PF09747.9 ORX94332.1 - 0.017 15.3 17.5 0.031 14.4 17.5 1.4 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) GAGA_bind PF06217.12 ORX94332.1 - 0.029 14.6 12.1 0.053 13.8 12.1 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family Coilin_N PF15862.5 ORX94332.1 - 0.054 13.3 19.2 0.13 12.1 19.2 1.6 1 0 0 1 1 1 0 Coilin N-terminus FmdE PF02663.14 ORX94332.1 - 0.092 12.8 5.0 0.15 12.1 3.8 1.9 2 0 0 2 2 1 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon AAA_11 PF13086.6 ORX94332.1 - 0.27 11.0 14.4 0.71 9.6 14.4 1.7 1 0 0 1 1 1 0 AAA domain Neur_chan_memb PF02932.16 ORX94332.1 - 1.1 9.3 8.5 1.8 8.5 8.5 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Otopetrin PF03189.13 ORX94332.1 - 1.2 7.8 5.6 2 7.2 5.6 1.2 1 0 0 1 1 1 0 Otopetrin DDHD PF02862.17 ORX94332.1 - 1.7 8.8 10.3 3.4 7.8 10.3 1.5 1 0 0 1 1 1 0 DDHD domain PA26 PF04636.13 ORX94332.1 - 3.3 6.5 14.0 5.9 5.7 14.0 1.4 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) LicD PF04991.13 ORX94332.1 - 4.9 7.2 12.4 51 3.9 11.4 2.5 2 0 0 2 2 2 0 LicD family CDC45 PF02724.14 ORX94332.1 - 5.6 5.1 22.7 8.7 4.5 22.7 1.2 1 0 0 1 1 1 0 CDC45-like protein CLN3 PF02487.17 ORX94332.1 - 7.9 5.4 11.7 15 4.4 11.2 1.7 2 0 0 2 2 2 0 CLN3 protein GFA PF04828.14 ORX94357.1 - 3.5e-20 72.2 0.1 5.2e-20 71.6 0.1 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zf-NADH-PPase PF09297.11 ORX94357.1 - 0.041 13.5 0.8 0.041 13.5 0.8 2.5 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Zn_ribbon_SprT PF17283.2 ORX94357.1 - 3.7 7.5 7.5 15 5.6 0.1 2.8 3 0 0 3 3 3 0 SprT-like zinc ribbon domain Ank_2 PF12796.7 ORX94358.1 - 1.4e-73 243.5 9.0 4e-11 43.3 0.0 17.1 7 4 11 18 18 18 16 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORX94358.1 - 2.3e-50 168.3 23.4 1.1e-07 32.3 0.0 23.6 18 5 9 27 27 27 11 Ankyrin repeats (many copies) Ank PF00023.30 ORX94358.1 - 1.7e-47 157.9 44.2 0.0012 19.2 0.1 24.4 24 3 1 25 25 25 11 Ankyrin repeat Ank_5 PF13857.6 ORX94358.1 - 3.5e-42 141.9 23.0 4.9e-09 36.3 0.1 22.6 20 6 4 24 24 24 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORX94358.1 - 6.3e-41 133.7 14.7 0.00042 20.5 0.0 24.3 25 3 1 26 26 26 5 Ankyrin repeat NACHT PF05729.12 ORX94358.1 - 2.1e-09 37.5 0.0 7.9e-09 35.6 0.0 2.0 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 ORX94358.1 - 2.6e-06 27.9 0.1 5.8e-05 23.5 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 ORX94358.1 - 4e-05 23.9 0.0 0.00024 21.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.9 ORX94358.1 - 0.011 14.9 0.0 0.019 14.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) IstB_IS21 PF01695.17 ORX94358.1 - 0.067 12.9 0.1 0.33 10.7 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein MARVEL PF01284.23 ORX94360.1 - 9.2e-08 32.2 17.6 1.3e-07 31.7 17.1 1.5 1 1 0 1 1 1 1 Membrane-associating domain LRR_6 PF13516.6 ORX94361.1 - 0.0022 17.9 0.1 0.0083 16.1 0.1 2.0 1 0 0 1 1 1 1 Leucine Rich repeat Polbeta PF18765.1 ORX94362.1 - 6.1e-06 26.2 0.0 1.3e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase RlaP PF10127.9 ORX94362.1 - 3.2e-05 23.6 0.3 0.00011 21.9 0.0 1.9 2 0 0 2 2 2 1 RNA repair pathway DNA polymerase beta family NTP_transf_2 PF01909.23 ORX94362.1 - 0.00016 21.9 0.0 0.00023 21.4 0.0 1.6 1 1 0 1 1 1 1 Nucleotidyltransferase domain Abhydrolase_4 PF08386.10 ORX94363.1 - 1.1e-13 51.1 0.0 3e-13 49.8 0.0 1.7 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.20 ORX94363.1 - 2.5e-11 43.7 0.9 5.6e-11 42.6 0.9 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold UPRTase PF14681.6 ORX94364.1 - 1.4e-13 50.8 0.0 2.7e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase AAA_17 PF13207.6 ORX94364.1 - 0.00097 19.6 0.2 0.13 12.7 0.2 2.5 1 1 0 1 1 1 1 AAA domain Pribosyltran PF00156.27 ORX94364.1 - 0.017 14.6 0.0 0.055 13.0 0.0 1.8 1 1 0 1 1 1 0 Phosphoribosyl transferase domain HAD PF12710.7 ORX94364.1 - 0.078 13.4 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Glyco_hydro_32N PF00251.20 ORX94365.1 - 3.7e-10 39.9 0.0 2.8e-08 33.7 0.0 2.1 1 1 1 2 2 2 2 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 ORX94365.1 - 3.4e-06 27.2 0.0 7.4e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal WD40 PF00400.32 ORX94396.1 - 2.8e-73 240.0 31.6 6e-14 52.2 1.9 7.2 6 1 1 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX94396.1 - 2.5e-28 98.2 1.2 9.5e-06 25.8 0.0 5.6 1 1 5 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 ORX94396.1 - 2.1e-16 59.8 4.6 0.0057 15.7 0.2 6.1 1 1 4 5 5 5 4 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 ORX94396.1 - 1.4e-12 47.0 8.9 0.11 11.1 0.0 5.0 1 1 3 5 5 5 5 Nucleoporin Nup120/160 BLUF PF04940.12 ORX94396.1 - 5.5e-08 32.8 0.0 1 9.5 0.0 6.2 3 2 3 6 6 6 1 Sensors of blue-light using FAD CDtoxinA PF03498.14 ORX94396.1 - 1.4e-07 31.2 0.0 0.18 11.4 0.0 4.2 2 1 2 4 4 4 3 Cytolethal distending toxin A/C domain WD40_like PF17005.5 ORX94396.1 - 2.6e-06 27.0 0.0 2.7 7.3 0.0 4.7 4 1 1 5 5 5 2 WD40-like domain Frtz PF11768.8 ORX94396.1 - 0.00033 19.1 0.0 6.1 5.0 0.0 4.2 2 2 0 3 3 3 2 WD repeat-containing and planar cell polarity effector protein Fritz PD40 PF07676.12 ORX94396.1 - 0.00037 20.3 5.7 30 4.7 0.1 5.6 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat DUF5643 PF18705.1 ORX94396.1 - 0.0023 17.9 0.0 62 3.6 0.0 4.3 4 0 0 4 4 4 0 Family of unknown function (DUF5643) RicinB_lectin_2 PF14200.6 ORX94396.1 - 0.0026 18.5 10.3 0.79 10.5 0.9 3.7 2 2 1 3 3 3 2 Ricin-type beta-trefoil lectin domain-like Me-amine-dh_H PF06433.11 ORX94396.1 - 0.016 14.1 0.0 7.1 5.4 0.0 2.9 2 1 0 3 3 3 0 Methylamine dehydrogenase heavy chain (MADH) LytR_cpsA_psr PF03816.14 ORX94396.1 - 0.022 14.9 0.1 67 3.6 0.0 4.1 3 2 0 4 4 4 0 Cell envelope-related transcriptional attenuator domain Prok-E2_E PF14462.6 ORX94396.1 - 0.18 11.6 1.3 8.7 6.2 0.1 2.5 2 0 0 2 2 2 0 Prokaryotic E2 family E DUF2415 PF10313.9 ORX94396.1 - 7.9 6.5 7.5 69 3.5 0.0 4.4 6 0 0 6 6 6 0 Uncharacterised protein domain (DUF2415) DUF2514 PF10721.9 ORX94398.1 - 0.013 15.6 1.7 0.015 15.3 1.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) RSF PF14876.6 ORX94398.1 - 0.04 12.9 0.0 0.04 12.9 0.0 1.2 1 0 0 1 1 1 0 Respiratory growth transcriptional regulator MAS20 PF02064.15 ORX94398.1 - 0.2 11.8 3.7 0.25 11.5 3.7 1.2 1 0 0 1 1 1 0 MAS20 protein import receptor APH PF01636.23 ORX94402.1 - 3.1e-10 40.4 0.0 5.3e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 ORX94402.1 - 0.0027 17.1 0.0 0.0043 16.4 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.11 ORX94402.1 - 0.015 14.2 0.0 0.027 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Choline_kinase PF01633.20 ORX94402.1 - 0.017 14.7 0.0 0.029 14.0 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 ORX94402.1 - 0.11 11.9 0.0 0.23 10.8 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family AA_permease_2 PF13520.6 ORX94415.1 - 1.1e-52 179.4 47.5 1.3e-52 179.0 47.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ORX94415.1 - 4.6e-23 81.5 37.0 6.5e-23 81.1 37.0 1.2 1 0 0 1 1 1 1 Amino acid permease Pyr_redox_3 PF13738.6 ORX94416.1 - 3.9e-15 55.9 0.1 1.9e-13 50.3 0.2 2.6 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 ORX94416.1 - 4.8e-14 51.7 0.0 2.3e-13 49.4 0.0 2.0 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 ORX94416.1 - 2.9e-11 43.1 0.0 5.9e-08 32.2 0.0 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 ORX94416.1 - 1.1e-10 41.2 0.0 2.2e-09 37.0 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORX94416.1 - 6.7e-06 26.2 2.0 2.7e-05 24.3 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 ORX94416.1 - 0.0011 19.5 1.8 0.66 10.6 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 ORX94416.1 - 0.0013 18.8 0.0 6.1 6.9 0.0 3.0 3 0 0 3 3 3 2 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.6 ORX94416.1 - 0.0017 18.4 0.5 0.8 9.7 0.1 3.5 4 0 0 4 4 4 1 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 ORX94416.1 - 0.0053 16.1 0.3 0.33 10.2 0.0 2.2 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 ORX94416.1 - 0.024 13.7 0.8 0.046 12.8 0.8 1.4 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.24 ORX94416.1 - 0.064 12.8 5.1 0.22 11.1 1.6 2.8 2 1 1 3 3 3 0 FAD dependent oxidoreductase 3HCDH_N PF02737.18 ORX94416.1 - 0.12 12.3 0.2 0.24 11.3 0.2 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 ORX94416.1 - 0.14 11.3 0.1 0.25 10.6 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain PCI PF01399.27 ORX94417.1 - 0.006 17.1 0.0 2.4 8.7 0.0 2.7 2 0 0 2 2 2 2 PCI domain Fungal_trans PF04082.18 ORX94418.1 - 4.1e-14 52.3 0.0 7.1e-14 51.5 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORX94418.1 - 7e-07 29.3 7.5 1.1e-06 28.6 7.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2HC5 PF06221.13 ORX94418.1 - 0.099 12.7 2.4 0.23 11.4 2.4 1.5 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type Aminotran_3 PF00202.21 ORX94419.1 - 6.9e-83 278.6 0.0 8.4e-83 278.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Nucleoporin_FG2 PF15967.5 ORX94419.1 - 0.18 10.3 0.0 0.26 9.8 0.0 1.1 1 0 0 1 1 1 0 Nucleoporin FG repeated region Helo_like_N PF17111.5 ORX94420.1 - 0.0064 15.9 0.1 0.0064 15.9 0.1 2.6 2 1 0 2 2 2 1 Fungal N-terminal domain of STAND proteins Toxin_2 PF00451.19 ORX94420.1 - 0.72 10.2 3.2 7 7.1 0.2 2.4 2 0 0 2 2 2 0 Scorpion short toxin, BmKK2 Melibiase PF02065.18 ORX94421.1 - 1.6e-28 99.7 0.0 2.2e-28 99.2 0.0 1.1 1 0 0 1 1 1 1 Melibiase Melibiase_2 PF16499.5 ORX94421.1 - 0.09 11.9 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Alpha galactosidase A Clr5 PF14420.6 ORX94422.1 - 5.1e-17 61.8 6.3 5.1e-17 61.8 6.3 2.1 3 0 0 3 3 3 1 Clr5 domain MFS_1 PF07690.16 ORX94423.1 - 5.6e-41 140.6 52.2 5.6e-41 140.6 52.2 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORX94423.1 - 2.2e-10 40.0 5.9 2.2e-10 40.0 5.9 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter Strabismus PF06638.11 ORX94423.1 - 1.2 7.7 2.5 1.8 7.1 2.5 1.2 1 0 0 1 1 1 0 Strabismus protein MspA PF09203.11 ORX94424.1 - 0.015 15.2 3.2 0.015 15.2 3.2 1.0 1 0 0 1 1 1 0 MspA Fil_haemagg PF05594.14 ORX94424.1 - 0.68 10.5 7.4 2 9.0 7.4 1.7 1 1 0 1 1 1 0 Haemagluttinin repeat Hexapep_2 PF14602.6 ORX94424.1 - 8.8 6.2 13.9 4.5e+03 -2.5 13.9 2.7 1 1 0 1 1 1 0 Hexapeptide repeat of succinyl-transferase Acetyltransf_7 PF13508.7 ORX94425.1 - 1.6e-09 38.1 0.1 5.2e-09 36.4 0.1 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORX94425.1 - 5.2e-08 33.1 0.0 9.8e-08 32.2 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ORX94425.1 - 6.1e-08 32.7 0.0 1.4e-07 31.5 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ORX94425.1 - 7.3e-06 25.9 0.0 1.2e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 ORX94425.1 - 0.0051 17.5 0.0 0.013 16.2 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 ORX94425.1 - 0.11 12.5 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 ORX94425.1 - 0.14 12.3 0.0 0.32 11.2 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase GMC_oxred_N PF00732.19 ORX94427.1 - 3.5e-78 263.0 0.0 4.7e-78 262.6 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 ORX94427.1 - 2.6e-33 115.6 0.0 5.6e-33 114.5 0.0 1.6 1 1 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 ORX94427.1 - 0.00034 19.8 0.1 0.00054 19.1 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 ORX94427.1 - 0.012 14.7 0.1 1.6 7.8 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_2 PF07992.14 ORX94427.1 - 0.014 14.7 0.0 0.029 13.6 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORX94427.1 - 0.063 13.8 0.8 1.3 9.6 0.2 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 ORX94427.1 - 0.067 12.4 0.5 0.12 11.6 0.1 1.5 2 0 0 2 2 2 0 Thi4 family DAO PF01266.24 ORX94427.1 - 0.11 12.1 1.8 0.55 9.8 1.7 2.0 1 1 0 1 1 1 0 FAD dependent oxidoreductase Ank_2 PF12796.7 ORX94428.1 - 5.7e-17 62.1 0.0 7.8e-08 32.8 0.0 4.3 3 1 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ORX94428.1 - 2.4e-10 39.7 0.0 0.23 12.1 0.0 7.2 8 0 0 8 8 8 2 Ankyrin repeat Ank_4 PF13637.6 ORX94428.1 - 3.6e-10 40.2 0.1 0.081 13.5 0.0 6.7 4 2 3 7 7 7 2 Ankyrin repeats (many copies) Ank PF00023.30 ORX94428.1 - 0.0021 18.4 0.1 14 6.4 0.0 5.1 7 0 0 7 7 7 1 Ankyrin repeat Ank_5 PF13857.6 ORX94428.1 - 0.0046 17.2 0.0 77 3.8 0.0 5.5 5 1 2 7 7 7 0 Ankyrin repeats (many copies) AOX PF01786.17 ORX94429.1 - 7.3e-95 316.6 0.6 8.8e-95 316.3 0.6 1.1 1 0 0 1 1 1 1 Alternative oxidase Peptidase_C9 PF01707.16 ORX94429.1 - 0.067 12.8 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Peptidase family C9 DUF1358 PF07096.11 ORX94429.1 - 0.11 12.5 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1358) Acylphosphatase PF00708.18 ORX94430.1 - 1.8e-14 53.9 0.5 6.4e-06 26.5 0.0 3.0 1 1 1 2 2 2 2 Acylphosphatase Antimicrobial14 PF08109.11 ORX94430.1 - 0.051 13.6 0.0 8 6.6 0.0 2.4 2 0 0 2 2 2 0 Lactocin 705 family IF-2 PF11987.8 ORX94430.1 - 0.061 13.5 0.1 0.26 11.4 0.0 2.0 1 1 0 2 2 2 0 Translation-initiation factor 2 CH PF00307.31 ORX94431.1 - 0.0015 18.7 0.1 0.005 17.0 0.0 1.9 1 1 1 2 2 2 1 Calponin homology (CH) domain Cas_APE2256 PF09651.10 ORX94431.1 - 0.0093 15.9 0.0 0.021 14.7 0.0 1.5 1 0 0 1 1 1 1 CRISPR-associated protein (Cas_APE2256) TAF8_C PF10406.9 ORX94431.1 - 0.017 15.7 0.1 0.045 14.3 0.1 1.7 1 0 0 1 1 1 0 Transcription factor TFIID complex subunit 8 C-term YopE_N PF09020.10 ORX94431.1 - 0.11 12.8 1.7 0.32 11.2 1.7 1.8 1 0 0 1 1 1 0 YopE, N terminal Ras PF00071.22 ORX94454.1 - 1.6e-34 118.8 0.1 2.2e-34 118.4 0.1 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORX94454.1 - 2.4e-10 40.6 0.0 6e-10 39.4 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase XPG_I PF00867.18 ORX94456.1 - 4.6e-23 81.4 0.0 9.9e-23 80.3 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 ORX94456.1 - 9.5e-18 64.5 0.0 2.3e-17 63.3 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.7 ORX94456.1 - 4.4e-05 23.1 0.0 6.3e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 XPG domain containing 5_3_exonuc PF01367.20 ORX94456.1 - 0.036 14.7 0.0 0.082 13.5 0.0 1.5 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold Tma16 PF11176.8 ORX94457.1 - 6.9e-51 172.0 1.7 8.9e-51 171.6 1.7 1.1 1 0 0 1 1 1 1 Translation machinery-associated protein 16 p450 PF00067.22 ORX94458.1 - 0.24 10.1 0.1 1.5 7.5 0.0 1.9 2 0 0 2 2 2 0 Cytochrome P450 CRAL_TRIO PF00650.20 ORX94460.1 - 3.3e-35 121.1 0.0 8.1e-35 119.9 0.0 1.6 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 ORX94460.1 - 1.9e-07 31.2 0.0 3.9e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 ORX94460.1 - 0.0025 18.0 0.0 0.0041 17.3 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Exo_endo_phos PF03372.23 ORX94461.1 - 1.5e-20 73.7 0.2 2e-19 70.1 0.2 2.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_8 PF13855.6 ORX94461.1 - 6.7e-08 32.2 10.3 5.5e-07 29.3 8.3 2.6 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 ORX94461.1 - 2e-07 31.2 11.0 0.00031 21.1 2.3 2.5 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORX94461.1 - 7.2 7.6 7.9 14 6.7 0.3 4.1 3 1 0 3 3 3 0 Leucine Rich Repeat Methyltransf_25 PF13649.6 ORX94462.1 - 1.8e-13 51.0 0.0 3.2e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORX94462.1 - 2.6e-11 44.0 0.0 5.3e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORX94462.1 - 9.3e-09 35.3 0.0 2.6e-08 33.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORX94462.1 - 1.9e-07 31.7 0.0 3.8e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORX94462.1 - 2.6e-06 27.3 0.0 4.4e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORX94462.1 - 3.6e-06 26.5 0.0 5.9e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.15 ORX94462.1 - 0.00012 22.0 0.0 0.0002 21.3 0.0 1.3 1 0 0 1 1 1 1 Hypothetical methyltransferase MTS PF05175.14 ORX94462.1 - 0.0014 18.2 0.0 0.0055 16.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase small domain Complex1_LYR PF05347.15 ORX94463.1 - 3.1e-06 27.1 0.3 5.1e-06 26.4 0.3 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 ORX94463.1 - 4.9e-06 27.2 0.8 6.6e-06 26.8 0.8 1.3 1 1 0 1 1 1 1 Complex1_LYR-like 4HBT_2 PF13279.6 ORX94464.1 - 6e-21 75.2 0.0 8.2e-21 74.8 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 ORX94464.1 - 0.047 14.0 0.0 0.096 13.1 0.0 1.5 1 1 0 1 1 1 0 Thioesterase superfamily DUF1741 PF08427.10 ORX94466.1 - 0.99 9.0 8.5 0.91 9.1 4.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1741) ELYS PF13934.6 ORX94471.1 - 1.3e-57 195.3 0.0 1.6e-57 195.0 0.0 1.0 1 0 0 1 1 1 1 Nuclear pore complex assembly RHH_4 PF13467.6 ORX94471.1 - 0.15 12.0 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 Ribbon-helix-helix domain Vps8 PF12816.7 ORX94514.1 - 1.8e-70 236.5 0.1 5.2e-70 235.0 0.1 1.8 1 0 0 1 1 1 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.20 ORX94514.1 - 9.7e-09 35.2 0.5 0.0012 18.7 0.2 3.5 3 0 0 3 3 3 3 Region in Clathrin and VPS zf-C3H2C3 PF17122.5 ORX94514.1 - 0.038 14.0 0.9 0.12 12.4 0.0 2.3 2 0 0 2 2 2 0 Zinc-finger zf-C3HC4_2 PF13923.6 ORX94514.1 - 0.19 11.6 0.6 1.1 9.2 0.0 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF3752 PF12572.8 ORX94515.1 - 5.9e-49 166.5 12.6 5.9e-49 166.5 12.6 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF3752) Dynamitin PF04912.14 ORX94515.1 - 0.0082 15.5 3.5 0.011 15.1 3.5 1.2 1 0 0 1 1 1 1 Dynamitin CSRNP_N PF16019.5 ORX94515.1 - 0.4 10.6 5.1 0.22 11.4 2.7 1.6 2 0 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus F-box-like PF12937.7 ORX94516.1 - 0.0018 18.1 0.0 0.0069 16.3 0.0 2.0 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 ORX94516.1 - 2.1 8.3 5.2 3.1 7.8 0.1 2.8 3 1 0 3 3 3 0 F-box domain DUF2099 PF09872.9 ORX94517.1 - 1.4 8.1 3.5 3 7.0 1.6 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2099) DUF4459 PF14673.6 ORX94518.1 - 0.056 13.4 0.0 0.096 12.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4459) FeS_assembly_P PF01883.19 ORX94519.1 - 4e-08 33.3 0.0 1.1e-07 31.9 0.0 1.8 1 1 0 1 1 1 1 Iron-sulfur cluster assembly protein Fungal_trans PF04082.18 ORX94520.1 - 3.4e-07 29.6 1.1 7.3e-07 28.5 0.3 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORX94520.1 - 7.4e-07 29.2 6.9 1.5e-06 28.2 6.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2020 PF09449.10 ORX94520.1 - 0.018 14.9 0.1 0.048 13.5 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF2020) peroxidase PF00141.23 ORX94522.1 - 3.7e-21 75.9 0.0 5.8e-21 75.2 0.0 1.3 1 0 0 1 1 1 1 Peroxidase Peroxidase_ext PF11895.8 ORX94522.1 - 0.014 15.3 0.0 0.035 14.0 0.0 1.7 1 0 0 1 1 1 0 Fungal peroxidase extension region Dus PF01207.17 ORX94524.1 - 1.6e-44 152.2 0.0 6.8e-44 150.2 0.0 1.8 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) Thump_like PF18096.1 ORX94524.1 - 0.024 14.6 0.2 1 9.3 0.0 2.5 2 0 0 2 2 2 0 THUMP domain-like EF-hand_1 PF00036.32 ORX94545.1 - 6.2e-09 34.8 0.0 0.0023 17.4 0.0 2.4 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 ORX94545.1 - 8.9e-08 32.5 0.0 1.8e-07 31.5 0.0 1.5 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 ORX94545.1 - 6.9e-07 28.7 0.0 0.0036 17.1 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 ORX94545.1 - 8e-07 28.3 0.0 0.015 14.7 0.0 2.4 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 ORX94545.1 - 2.3e-06 27.3 0.0 0.089 12.7 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair Diedel PF13164.6 ORX94545.1 - 0.6 10.6 18.8 0.93 10.0 18.8 1.4 1 0 0 1 1 1 0 Diedel p450 PF00067.22 ORX94548.1 - 2.6e-40 138.6 0.0 6.7e-40 137.2 0.0 1.5 1 1 1 2 2 2 1 Cytochrome P450 Membralin PF09746.9 ORX94548.1 - 0.096 11.7 0.9 0.78 8.7 0.5 2.1 2 0 0 2 2 2 0 Tumour-associated protein MFS_1 PF07690.16 ORX94549.1 - 1.1e-33 116.6 66.9 2.9e-29 102.1 43.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily HET PF06985.11 ORX94551.1 - 5.7e-19 68.9 0.0 5.9e-19 68.9 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) AATase PF07247.12 ORX94552.1 - 1.1e-06 27.5 0.1 1.5e-06 27.0 0.1 1.2 1 0 0 1 1 1 1 Alcohol acetyltransferase Tri3 PF07428.11 ORX94552.1 - 0.15 10.9 0.2 0.21 10.5 0.2 1.1 1 0 0 1 1 1 0 15-O-acetyltransferase Tri3 RNA_pol_3_Rpc31 PF11705.8 ORX94553.1 - 0.0022 18.3 19.9 0.0027 18.0 19.9 1.2 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 Nop14 PF04147.12 ORX94553.1 - 0.04 12.2 20.8 0.045 12.0 20.8 1.1 1 0 0 1 1 1 0 Nop14-like family Mpp10 PF04006.12 ORX94553.1 - 0.044 12.2 19.8 0.062 11.8 19.8 1.2 1 0 0 1 1 1 0 Mpp10 protein Pinin_SDK_N PF04697.13 ORX94553.1 - 0.045 14.4 18.5 0.063 13.9 18.5 1.2 1 0 0 1 1 1 0 pinin/SDK conserved region DNA_pol_phi PF04931.13 ORX94553.1 - 0.46 8.5 18.6 0.51 8.4 18.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi eIF-3_zeta PF05091.12 ORX94553.1 - 0.83 8.6 13.3 0.94 8.4 13.3 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) NOA36 PF06524.12 ORX94553.1 - 0.87 8.8 12.7 1.3 8.3 12.7 1.3 1 0 0 1 1 1 0 NOA36 protein Merozoite_SPAM PF07133.11 ORX94553.1 - 0.9 9.5 31.4 1.4 8.9 31.4 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) RR_TM4-6 PF06459.12 ORX94553.1 - 1 9.1 18.3 1.4 8.7 18.3 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Dsh_C PF12316.8 ORX94553.1 - 1.9 8.9 9.9 2.4 8.5 9.9 1.3 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal DUF2201_N PF13203.6 ORX94553.1 - 1.9 8.0 11.1 2.4 7.7 11.1 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain FAM60A PF15396.6 ORX94553.1 - 2.6 8.0 11.5 3.5 7.6 11.5 1.1 1 0 0 1 1 1 0 Protein Family FAM60A CLN3 PF02487.17 ORX94553.1 - 4.7 6.1 4.8 6.5 5.7 4.8 1.1 1 0 0 1 1 1 0 CLN3 protein COPI_C PF06957.11 ORX94553.1 - 7.4 5.2 12.5 9.3 4.9 12.5 1.1 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus CDC45 PF02724.14 ORX94553.1 - 9 4.5 22.8 11 4.2 22.8 1.2 1 0 0 1 1 1 0 CDC45-like protein Glyco_hydro_92 PF07971.12 ORX94596.1 - 1.9e-33 116.1 0.0 2.1e-33 116.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 p450 PF00067.22 ORX94597.1 - 7.3e-58 196.4 0.0 9.3e-58 196.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 ORX94599.1 - 2.4e-38 132.0 40.1 4.5e-37 127.8 40.1 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 ORX94599.1 - 2.9e-14 52.4 13.8 3.7e-14 52.1 13.8 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 ORX94599.1 - 7.8e-11 41.5 4.9 7.8e-11 41.5 4.9 2.4 2 1 0 2 2 2 2 Sugar (and other) transporter FSH1 PF03959.13 ORX94600.1 - 3.8e-23 82.3 0.0 6.6e-23 81.5 0.0 1.3 1 1 0 1 1 1 1 Serine hydrolase (FSH1) ketoacyl-synt PF00109.26 ORX94601.1 - 1.4e-69 234.5 0.1 2.5e-69 233.7 0.1 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 ORX94601.1 - 2.9e-55 187.0 0.0 5.2e-55 186.1 0.0 1.4 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.21 ORX94601.1 - 7e-42 144.0 0.0 2.4e-41 142.3 0.0 1.8 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 ORX94601.1 - 1.6e-36 124.9 0.0 3.3e-36 123.9 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.6 ORX94601.1 - 2.7e-36 125.4 0.0 4.1e-36 124.8 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase ADH_zinc_N_2 PF13602.6 ORX94601.1 - 2.2e-18 67.6 0.1 2.7e-17 64.0 0.0 2.8 3 0 0 3 3 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 ORX94601.1 - 7.4e-18 64.8 1.5 1.5e-17 63.8 0.2 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.12 ORX94601.1 - 2.3e-16 60.4 0.0 5.9e-16 59.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 ORX94601.1 - 1.2e-15 57.9 0.0 9.5e-15 55.0 0.0 2.4 1 1 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_11 PF08241.12 ORX94601.1 - 1.5e-10 41.6 0.0 4.5e-10 40.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 ORX94601.1 - 1.6e-10 41.2 0.2 1.2e-09 38.4 0.0 2.5 2 0 0 2 2 2 1 Phosphopantetheine attachment site Methyltransf_25 PF13649.6 ORX94601.1 - 2.6e-10 40.9 0.0 1.2e-09 38.7 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORX94601.1 - 8.6e-10 38.6 0.0 3.3e-09 36.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain adh_short PF00106.25 ORX94601.1 - 9.5e-09 35.0 0.0 3.4e-08 33.2 0.0 1.9 1 0 0 1 1 1 1 short chain dehydrogenase Methyltransf_23 PF13489.6 ORX94601.1 - 1.8e-06 27.9 0.0 4.7e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORX94601.1 - 0.00012 21.5 0.0 0.00027 20.3 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family adh_short_C2 PF13561.6 ORX94601.1 - 0.00034 20.3 0.0 0.00071 19.2 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ADH_N PF08240.12 ORX94601.1 - 0.027 14.4 0.0 0.078 12.9 0.0 1.8 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain ACP_syn_III PF08545.10 ORX94601.1 - 0.027 14.3 0.4 0.08 12.8 0.4 1.8 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.23 ORX94601.1 - 0.071 12.5 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 Thiolase, N-terminal domain DUF3328 PF11807.8 ORX94602.1 - 9.4e-13 48.4 0.8 1.1e-12 48.2 0.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Peptidase_M43 PF05572.13 ORX94603.1 - 5e-06 26.5 1.2 1.1e-05 25.4 0.3 2.0 2 1 0 2 2 2 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 ORX94603.1 - 0.0024 18.1 0.3 0.0048 17.1 0.2 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 ORX94603.1 - 0.015 15.8 0.6 0.057 13.9 0.6 2.1 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like SUR7 PF06687.12 ORX94604.1 - 0.01 15.4 0.2 0.013 15.2 0.2 1.2 1 0 0 1 1 1 0 SUR7/PalI family DUF1772 PF08592.11 ORX94604.1 - 0.86 9.9 8.0 9.4 6.6 8.1 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF1772) YccF PF03733.13 ORX94604.1 - 2.4 8.9 14.1 1.6 9.5 0.9 3.7 3 1 1 4 4 4 0 Inner membrane component domain Collagen PF01391.18 ORX94606.1 - 0.037 13.8 0.6 4 7.3 0.1 2.7 1 1 1 2 2 2 0 Collagen triple helix repeat (20 copies) FMO-like PF00743.19 ORX94632.1 - 5.3e-26 91.1 0.1 8.9e-16 57.4 0.1 2.0 1 1 1 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 ORX94632.1 - 1.9e-11 43.8 0.0 2.8e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORX94632.1 - 2e-08 34.3 0.0 8.8e-08 32.3 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 ORX94632.1 - 9.5e-06 25.7 0.0 0.0044 17.0 0.0 2.1 1 1 1 2 2 2 2 FAD-NAD(P)-binding DAO PF01266.24 ORX94632.1 - 1.5e-05 24.8 0.0 0.048 13.2 0.0 2.0 1 1 1 2 2 2 2 FAD dependent oxidoreductase K_oxygenase PF13434.6 ORX94632.1 - 4.2e-05 22.8 0.2 0.0039 16.4 0.1 2.0 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 ORX94632.1 - 7e-05 22.2 0.0 0.016 14.5 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_2 PF03446.15 ORX94632.1 - 0.00068 19.8 0.0 0.00083 19.6 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase HI0933_like PF03486.14 ORX94632.1 - 0.0013 17.6 0.0 0.0018 17.0 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 ORX94632.1 - 0.0028 18.2 0.0 0.0056 17.2 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 ORX94632.1 - 0.0071 15.7 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 ORX94632.1 - 0.0098 15.2 0.1 0.027 13.7 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain IlvN PF07991.12 ORX94632.1 - 0.016 14.7 0.0 0.034 13.7 0.0 1.5 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain 3HCDH_N PF02737.18 ORX94632.1 - 0.018 15.0 0.0 0.029 14.2 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 ORX94632.1 - 0.019 14.9 0.0 0.033 14.2 0.0 1.3 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus AlaDh_PNT_C PF01262.21 ORX94632.1 - 0.033 13.5 0.0 0.04 13.2 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.16 ORX94632.1 - 0.053 13.2 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA XdhC_C PF13478.6 ORX94632.1 - 0.073 13.6 0.0 0.083 13.4 0.0 1.3 1 0 0 1 1 1 0 XdhC Rossmann domain UDPG_MGDP_dh_N PF03721.14 ORX94632.1 - 0.13 11.8 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Thi4 PF01946.17 ORX94632.1 - 0.14 11.4 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 Thi4 family adh_short PF00106.25 ORX94632.1 - 0.14 11.6 0.0 0.18 11.2 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase Shikimate_DH PF01488.20 ORX94632.1 - 0.16 12.1 0.0 0.25 11.4 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Glu_dehyd_C PF16912.5 ORX94632.1 - 0.24 10.9 0.0 0.43 10.0 0.0 1.4 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus FAD_binding_4 PF01565.23 ORX94635.1 - 7.5e-26 90.5 0.2 1.5e-25 89.6 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 ORX94635.1 - 0.0033 17.5 0.0 0.0075 16.4 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like NTF2 PF02136.20 ORX94636.1 - 0.011 16.3 0.0 0.013 16.1 0.0 1.2 1 0 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain SnoaL_3 PF13474.6 ORX94636.1 - 0.02 15.1 0.0 0.023 15.0 0.0 1.1 1 0 0 1 1 1 0 SnoaL-like domain SnoaL_2 PF12680.7 ORX94636.1 - 0.067 13.8 0.0 0.072 13.7 0.0 1.2 1 0 0 1 1 1 0 SnoaL-like domain adh_short PF00106.25 ORX94639.1 - 2.3e-25 89.2 0.5 3.2e-25 88.7 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORX94639.1 - 6.6e-22 78.2 0.3 7.8e-22 78.0 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORX94639.1 - 3.4e-10 40.1 0.1 4.1e-10 39.9 0.1 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 ORX94639.1 - 1.7e-05 24.8 0.0 3.5e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 ORX94639.1 - 0.014 15.6 0.2 3.7 7.8 0.1 2.2 1 1 1 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Toprim_Crpt PF13342.6 ORX94639.1 - 0.057 13.4 3.0 6.5 6.8 0.1 3.7 3 1 1 4 4 4 0 C-terminal repeat of topoisomerase EFG_C PF00679.24 ORX94639.1 - 0.083 12.9 0.1 0.53 10.3 0.0 2.2 2 0 0 2 2 2 0 Elongation factor G C-terminus Epimerase PF01370.21 ORX94639.1 - 0.14 11.6 0.3 0.27 10.6 0.3 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family WD-3 PF09765.9 ORX94639.1 - 0.17 11.1 0.1 0.49 9.7 0.0 1.7 3 0 0 3 3 3 0 WD-repeat region CoA_binding_2 PF13380.6 ORX94640.1 - 2.7e-27 95.6 0.0 3.2e-27 95.3 0.0 1.1 1 0 0 1 1 1 1 CoA binding domain zf-His_Me_endon PF05551.11 ORX94642.1 - 0.023 14.9 4.1 0.033 14.4 4.1 1.3 1 0 0 1 1 1 0 Zinc-binding loop region of homing endonuclease PAXIP1_C PF15364.6 ORX94642.1 - 0.031 14.6 1.0 0.044 14.1 1.0 1.2 1 0 0 1 1 1 0 PAXIP1-associated-protein-1 C term PTIP binding protein ATP_synt_H PF05493.13 ORX94643.1 - 1.5e-22 79.8 4.4 1.7e-22 79.6 4.4 1.0 1 0 0 1 1 1 1 ATP synthase subunit H Yip1 PF04893.17 ORX94643.1 - 0.23 11.2 6.9 0.26 11.0 6.9 1.1 1 0 0 1 1 1 0 Yip1 domain DUF4131 PF13567.6 ORX94643.1 - 0.41 10.3 3.0 0.43 10.2 3.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Arv1 PF04161.13 ORX94644.1 - 8.3e-73 245.0 0.0 9.6e-73 244.8 0.0 1.0 1 0 0 1 1 1 1 Arv1-like family YqeY PF09424.10 ORX94647.1 - 1.2e-24 87.0 0.1 1.3e-24 86.9 0.1 1.0 1 0 0 1 1 1 1 Yqey-like protein Nucleoporin_N PF08801.11 ORX94648.1 - 1.2e-87 294.4 0.0 1.8e-87 293.9 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.14 ORX94648.1 - 1.7e-47 162.5 2.6 2.1e-47 162.2 1.2 1.7 1 1 0 2 2 2 1 Non-repetitive/WGA-negative nucleoporin C-terminal SRI PF08236.11 ORX94648.1 - 0.2 11.8 0.0 0.41 10.8 0.0 1.4 1 0 0 1 1 1 0 SRI (Set2 Rpb1 interacting) domain DUF2781 PF10914.8 ORX94649.1 - 1.2e-37 129.6 5.0 1.4e-37 129.4 5.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) Fungal_trans PF04082.18 ORX94650.1 - 4.4e-73 245.6 0.4 5.7e-73 245.2 0.4 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short_C2 PF13561.6 ORX94662.1 - 6.2e-46 156.8 0.2 2.6e-40 138.5 0.0 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORX94662.1 - 1.5e-43 148.5 0.1 1.9e-43 148.2 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORX94662.1 - 1.6e-14 54.3 0.0 2.2e-14 53.8 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ORX94662.1 - 1.5e-05 24.6 0.0 8.5e-05 22.1 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Ribosomal_L12_N PF16320.5 ORX94662.1 - 0.029 14.1 0.1 0.066 12.9 0.1 1.6 1 0 0 1 1 1 0 Ribosomal protein L7/L12 dimerisation domain DUF1776 PF08643.10 ORX94662.1 - 0.19 11.1 0.0 0.24 10.8 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Meth_synt_2 PF01717.18 ORX94664.1 - 1.1e-153 511.3 0.0 1.7e-147 490.9 0.0 2.4 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 ORX94664.1 - 9.1e-124 413.0 0.0 2.6e-117 391.8 0.0 2.6 3 0 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain URO-D PF01208.17 ORX94664.1 - 8.2e-05 21.9 0.1 0.037 13.2 0.0 2.9 3 0 0 3 3 3 2 Uroporphyrinogen decarboxylase (URO-D) Bac_small_YrzI PF09501.10 ORX94664.1 - 0.49 10.6 3.1 1.6 9.0 3.1 1.9 1 0 0 1 1 1 0 Probable sporulation protein (Bac_small_yrzI) Methyltransf_23 PF13489.6 ORX94668.1 - 4.5e-15 55.9 0.0 6.6e-15 55.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORX94668.1 - 9.9e-08 32.6 0.0 1.7e-05 25.4 0.0 2.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORX94668.1 - 2.3e-07 30.8 0.0 0.0069 16.2 0.0 2.4 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 ORX94668.1 - 6.5e-06 26.7 0.0 0.00012 22.6 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORX94668.1 - 4.7e-05 24.1 0.0 0.0069 17.1 0.0 2.6 2 1 1 3 3 3 1 Methyltransferase domain RRM_1 PF00076.22 ORX94671.1 - 1.8e-05 24.5 0.0 0.11 12.4 0.0 2.6 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1929 PF09118.11 ORX94672.1 - 3.9e-22 78.3 0.4 9e-22 77.2 0.4 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_6 PF13964.6 ORX94672.1 - 4.9e-17 61.5 5.8 0.0003 21.0 0.0 5.0 3 1 2 5 5 5 3 Kelch motif PAN_1 PF00024.26 ORX94672.1 - 5.7e-16 58.3 5.2 1.8e-07 31.0 0.5 2.4 2 0 0 2 2 2 2 PAN domain Kelch_2 PF07646.15 ORX94672.1 - 5.2e-11 42.1 0.0 9.1e-05 22.3 0.0 4.6 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.25 ORX94672.1 - 2.6e-10 39.7 0.2 6.4e-06 25.6 0.0 4.4 4 0 0 4 4 4 1 Kelch motif Glyoxal_oxid_N PF07250.11 ORX94672.1 - 1.1e-07 31.3 0.0 0.00094 18.4 0.0 2.6 2 1 0 2 2 2 2 Glyoxal oxidase N-terminus Kelch_4 PF13418.6 ORX94672.1 - 2.9e-05 24.0 16.4 0.048 13.7 0.3 5.9 5 2 0 5 5 5 2 Galactose oxidase, central domain PAN_4 PF14295.6 ORX94672.1 - 0.00039 20.3 5.7 0.22 11.5 0.5 2.7 2 0 0 2 2 2 2 PAN domain MANEC PF07502.14 ORX94672.1 - 0.32 11.3 6.0 4.6 7.6 0.3 2.4 2 0 0 2 2 2 0 MANEC domain DUF824 PF05688.11 ORX94672.1 - 0.8 9.6 3.3 0.9 9.4 1.1 2.2 2 0 0 2 2 2 0 Salmonella repeat of unknown function (DUF824) RRM_1 PF00076.22 ORX94673.1 - 1.7e-08 34.1 0.0 4e-05 23.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SCAB-Ig PF16709.5 ORX94673.1 - 0.13 12.3 0.0 0.78 9.8 0.0 2.1 2 0 0 2 2 2 0 Ig domain of plant-specific actin-binding protein LAT PF15234.6 ORX94675.1 - 0.64 9.7 4.8 0.27 10.9 0.2 2.3 3 0 0 3 3 3 0 Linker for activation of T-cells DIOX_N PF14226.6 ORX94715.1 - 2e-17 64.0 0.0 3e-17 63.4 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 ORX94715.1 - 9.5e-16 58.1 0.0 2.8e-15 56.6 0.0 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily SKG6 PF08693.10 ORX94715.1 - 0.0016 17.8 0.8 0.003 16.9 0.8 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Mei4 PF13971.6 ORX94716.1 - 0.05 13.1 0.2 0.59 9.6 0.0 2.4 3 0 0 3 3 3 0 Meiosis-specific protein Mei4 CCDC85 PF10226.9 ORX94716.1 - 0.053 13.2 0.4 0.1 12.3 0.1 1.6 2 0 0 2 2 2 0 CCDC85 family Baculo_PP31 PF05311.11 ORX94716.1 - 0.097 12.2 0.2 0.27 10.7 0.0 1.8 2 0 0 2 2 2 0 Baculovirus 33KDa late protein (PP31) SpoIIE PF07228.12 ORX94716.1 - 0.12 12.3 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 Stage II sporulation protein E (SpoIIE) Jnk-SapK_ap_N PF09744.9 ORX94716.1 - 0.12 12.5 0.2 0.31 11.3 0.2 1.6 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Uds1 PF15456.6 ORX94716.1 - 3.2 7.9 7.7 0.14 12.3 0.3 2.4 3 0 0 3 3 3 0 Up-regulated During Septation PBP PF01161.20 ORX94717.1 - 6.6e-09 36.2 0.0 1.1e-08 35.4 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein DUF5137 PF17220.3 ORX94717.1 - 0.05 14.5 0.7 2.6 9.0 0.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF5137) Ribosomal_L4 PF00573.22 ORX94718.1 - 1.1e-43 149.2 0.0 1.4e-43 148.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family IF3_C PF00707.22 ORX94719.1 - 4e-08 33.1 0.1 8e-08 32.1 0.1 1.5 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain mIF3 PF14877.6 ORX94719.1 - 0.0024 17.6 0.0 0.0073 16.0 0.0 1.9 1 1 0 1 1 1 1 Mitochondrial translation initiation factor IF3_N PF05198.16 ORX94719.1 - 0.012 15.9 0.0 0.024 14.9 0.0 1.5 1 0 0 1 1 1 0 Translation initiation factor IF-3, N-terminal domain ATG16 PF08614.11 ORX94720.1 - 3.2e-50 171.2 11.3 3.8e-50 170.9 11.3 1.1 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Golgin_A5 PF09787.9 ORX94720.1 - 5.2e-05 22.9 4.1 6.2e-05 22.6 4.1 1.3 1 0 0 1 1 1 1 Golgin subfamily A member 5 CCDC144C PF14915.6 ORX94720.1 - 0.00082 18.6 17.7 0.0011 18.1 17.7 1.1 1 0 0 1 1 1 1 CCDC144C protein coiled-coil region SlyX PF04102.12 ORX94720.1 - 0.026 15.1 5.1 0.026 15.1 5.1 3.1 1 1 2 3 3 3 0 SlyX Lzipper-MIP1 PF14389.6 ORX94720.1 - 0.028 14.7 3.2 0.028 14.7 3.2 2.0 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 CASP_C PF08172.12 ORX94720.1 - 0.034 13.5 9.7 0.058 12.7 9.7 1.3 1 0 0 1 1 1 0 CASP C terminal YqgB PF11036.8 ORX94720.1 - 0.049 13.4 2.6 0.088 12.5 1.2 2.0 2 0 0 2 2 2 0 Virulence promoting factor DUF1338 PF07063.13 ORX94720.1 - 0.93 8.6 5.3 0.3 10.2 2.6 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1338) UPF0242 PF06785.11 ORX94720.1 - 1.6 8.8 18.2 0.45 10.6 6.5 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF4600 PF15372.6 ORX94720.1 - 1.8 9.0 13.8 2.6 8.5 12.3 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4600) AAA_13 PF13166.6 ORX94720.1 - 2.8 6.5 9.0 3.8 6.0 9.0 1.1 1 0 0 1 1 1 0 AAA domain TPR_MLP1_2 PF07926.12 ORX94720.1 - 4.2 7.4 22.6 0.29 11.2 9.7 2.7 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein CENP-H PF05837.12 ORX94720.1 - 4.5 7.7 19.8 0.35 11.3 3.1 2.4 1 1 1 2 2 2 0 Centromere protein H (CENP-H) PRKG1_interact PF15898.5 ORX94720.1 - 4.7 8.2 20.3 12 6.9 17.5 2.5 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain YabA PF06156.13 ORX94720.1 - 6.9 7.4 14.9 3.1 8.5 5.2 2.2 1 1 1 2 2 2 0 Initiation control protein YabA CENP-F_leu_zip PF10473.9 ORX94720.1 - 8.2 6.5 21.7 14 5.7 8.9 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6_N PF17675.1 ORX94720.1 - 8.8 6.9 25.4 1.4e+02 3.0 23.4 2.8 2 1 0 2 2 2 0 Apg6 coiled-coil region adh_short PF00106.25 ORX94721.1 - 0.0003 20.3 0.2 0.13 11.7 0.2 2.7 1 1 1 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORX94721.1 - 0.026 14.1 0.2 1 8.9 0.2 2.1 1 1 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORX94722.1 - 2.6e-22 79.3 0.0 4.9e-22 78.4 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORX94722.1 - 1.7e-15 57.2 0.0 2.3e-15 56.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase BBE PF08031.12 ORX94723.1 - 0.00012 22.1 0.0 0.00013 22.0 0.0 1.2 1 0 0 1 1 1 1 Berberine and berberine like JAB PF01398.21 ORX94725.1 - 1e-30 106.1 0.1 2e-30 105.2 0.1 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease CSN5_C PF18323.1 ORX94725.1 - 6.1e-17 62.3 0.2 2.4e-16 60.4 0.2 2.0 1 1 0 1 1 1 1 Cop9 signalosome subunit 5 C-terminal domain Prok-JAB PF14464.6 ORX94725.1 - 6.2e-06 26.0 0.0 1.2e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.13 ORX94725.1 - 0.011 15.7 0.0 0.02 15.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) tRNA-synt_2 PF00152.20 ORX94746.1 - 1.2e-77 261.1 0.5 1.6e-77 260.7 0.5 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 ORX94746.1 - 1.1e-06 28.5 0.0 3.7e-05 23.6 0.0 2.5 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 ORX94746.1 - 1.2e-05 25.0 0.2 0.013 15.0 0.1 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Hexokinase_2 PF03727.16 ORX94747.1 - 1.6e-82 276.5 0.0 2.1e-82 276.2 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 ORX94747.1 - 1.6e-71 240.3 0.0 2.6e-71 239.7 0.0 1.3 1 0 0 1 1 1 1 Hexokinase DUF1100 PF06500.11 ORX94749.1 - 6.6e-11 41.6 0.0 9.5e-11 41.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Abhydrolase_1 PF00561.20 ORX94749.1 - 4.8e-05 23.1 0.4 0.026 14.2 0.4 2.3 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ORX94749.1 - 7.2e-05 22.2 0.1 0.00016 21.1 0.0 1.5 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ORX94749.1 - 0.00018 22.2 0.1 0.00041 21.0 0.1 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family USP8_dimer PF08969.11 ORX94749.1 - 0.00058 20.0 0.2 0.0011 19.2 0.2 1.4 1 0 0 1 1 1 1 USP8 dimerisation domain Esterase PF00756.20 ORX94749.1 - 0.0006 19.5 0.0 0.005 16.5 0.0 2.0 1 1 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.16 ORX94749.1 - 0.00094 19.0 0.0 0.0018 18.1 0.0 1.4 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase BAAT_C PF08840.11 ORX94749.1 - 0.0073 16.2 0.0 0.014 15.4 0.0 1.4 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal AXE1 PF05448.12 ORX94749.1 - 0.078 11.6 0.0 0.78 8.3 0.0 2.1 1 1 1 2 2 2 0 Acetyl xylan esterase (AXE1) SET PF00856.28 ORX94752.1 - 0.0094 16.4 0.0 0.11 12.9 0.0 2.3 1 1 0 1 1 1 1 SET domain Cation_efflux PF01545.21 ORX94755.1 - 5.3e-47 160.1 8.2 5.3e-47 160.1 8.2 2.3 2 0 0 2 2 2 1 Cation efflux family Glyco_trans_4_4 PF13579.6 ORX94756.1 - 4.3e-06 27.3 2.3 7.4e-06 26.5 2.3 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.6 ORX94756.1 - 8e-06 26.3 0.0 3e-05 24.5 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 ORX94756.1 - 0.00014 21.4 0.0 0.00043 19.9 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 ORX94756.1 - 0.00015 21.8 1.8 0.00027 21.0 1.8 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 TFIIIC_delta PF12657.7 ORX94757.1 - 1.9e-33 116.0 0.4 2.3e-31 109.2 0.0 3.3 3 0 0 3 3 3 1 Transcription factor IIIC subunit delta N-term zf-TFIIIC PF12660.7 ORX94757.1 - 9.7e-30 102.5 0.1 2.5e-29 101.2 0.1 1.7 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex HET PF06985.11 ORX94759.1 - 2.8e-17 63.4 0.0 4.4e-17 62.8 0.0 1.3 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) AA_permease_2 PF13520.6 ORX94760.1 - 0.0053 15.6 6.7 0.0053 15.6 6.7 1.3 1 1 0 1 1 1 1 Amino acid permease DUF485 PF04341.12 ORX94760.1 - 0.023 14.6 2.4 0.03 14.3 2.4 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF485 Fig1 PF12351.8 ORX94760.1 - 0.088 12.7 2.1 0.11 12.4 2.1 1.0 1 0 0 1 1 1 0 Ca2+ regulator and membrane fusion protein Fig1 DUF4131 PF13567.6 ORX94760.1 - 0.15 11.7 0.1 0.16 11.6 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) SPC25 PF06703.11 ORX94760.1 - 0.2 11.4 0.2 0.24 11.2 0.2 1.1 1 0 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Glyco_hydro_18 PF00704.28 ORX94788.1 - 0.17 11.6 0.0 0.19 11.5 0.0 1.0 1 0 0 1 1 1 0 Glycosyl hydrolases family 18 FAD_binding_3 PF01494.19 ORX94789.1 - 1.1e-23 84.0 1.8 2.4e-23 82.9 1.8 1.4 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 ORX94789.1 - 1.6e-07 30.9 2.1 2.1e-06 27.2 2.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORX94789.1 - 3.2e-07 30.5 0.4 9.7e-07 28.9 0.4 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 ORX94789.1 - 9e-07 28.3 2.2 1.7e-06 27.4 2.2 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 ORX94789.1 - 1.3e-05 25.0 1.9 1.3e-05 25.0 1.9 2.4 1 1 1 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 ORX94789.1 - 8.3e-05 22.0 1.6 0.00074 18.9 0.7 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 ORX94789.1 - 0.00028 20.2 0.4 0.00028 20.2 0.4 1.7 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.7 ORX94789.1 - 0.00037 20.0 0.9 0.00059 19.3 0.9 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 ORX94789.1 - 0.0012 19.4 0.8 0.0027 18.2 0.8 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 ORX94789.1 - 0.0013 18.0 0.8 0.0013 18.0 0.8 1.7 2 0 0 2 2 2 1 Glucose inhibited division protein A Trp_halogenase PF04820.14 ORX94789.1 - 0.002 17.1 3.8 0.068 12.0 0.3 2.5 2 1 0 2 2 2 2 Tryptophan halogenase Lycopene_cycl PF05834.12 ORX94789.1 - 0.002 17.2 3.2 0.026 13.6 3.2 2.0 1 1 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.14 ORX94789.1 - 0.0027 16.5 2.1 0.0031 16.3 0.8 1.6 2 0 0 2 2 2 1 HI0933-like protein Amino_oxidase PF01593.24 ORX94789.1 - 0.0071 15.7 2.7 0.071 12.4 0.3 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase ApbA PF02558.16 ORX94789.1 - 0.012 15.3 0.1 0.024 14.3 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA SE PF08491.10 ORX94789.1 - 0.029 13.4 0.0 0.17 10.9 0.0 2.0 1 1 0 1 1 1 0 Squalene epoxidase AlaDh_PNT_C PF01262.21 ORX94789.1 - 0.038 13.3 0.5 0.074 12.3 0.5 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Abhydro_lipase PF04083.16 ORX94789.1 - 0.06 12.9 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region Rossmann-like PF10727.9 ORX94789.1 - 0.18 11.6 1.5 0.24 11.3 0.3 1.9 2 0 0 2 2 2 0 Rossmann-like domain MCRA PF06100.11 ORX94789.1 - 0.19 10.5 0.1 0.43 9.3 0.3 1.4 2 0 0 2 2 2 0 MCRA family adh_short PF00106.25 ORX94790.1 - 8.3e-14 51.5 0.5 1.3e-13 50.9 0.5 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORX94790.1 - 2e-09 37.4 0.7 2.3e-09 37.2 0.7 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 ORX94790.1 - 8.4e-07 29.1 0.6 1.3e-06 28.5 0.6 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 ORX94790.1 - 1.1e-06 28.4 0.6 1.7e-06 27.7 0.6 1.3 1 0 0 1 1 1 1 NmrA-like family KR PF08659.10 ORX94790.1 - 1.2e-05 25.4 1.1 1.6e-05 24.9 0.2 1.7 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 ORX94790.1 - 0.0053 16.3 0.1 0.0077 15.7 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.20 ORX94790.1 - 0.015 15.4 0.6 0.031 14.4 0.6 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus GDP_Man_Dehyd PF16363.5 ORX94790.1 - 0.028 13.8 0.0 0.038 13.4 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase MFS_1 PF07690.16 ORX94791.1 - 7.6e-49 166.5 36.2 7.6e-49 166.5 36.2 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORX94791.1 - 1.5e-16 60.3 5.1 1.5e-16 60.3 5.1 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 ORX94791.1 - 1.3e-07 30.5 1.0 1.3e-07 30.5 1.0 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 ORX94791.1 - 0.0032 15.8 6.1 0.34 9.1 4.0 3.4 2 1 0 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family Mso1_Sec1_bdg PF14475.6 ORX94812.1 - 3.2e-21 74.6 0.1 6.3e-21 73.7 0.1 1.5 1 0 0 1 1 1 1 Sec1-binding region of Mso1 Abp2 PF09441.10 ORX94813.1 - 1.4e-85 285.6 0.0 2.2e-85 285.0 0.0 1.3 1 0 0 1 1 1 1 ARS binding protein 2 p450 PF00067.22 ORX94815.1 - 1.7e-65 221.6 0.0 2.1e-65 221.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HgmA PF04209.13 ORX94816.1 - 6.9e-154 512.6 0.1 7.8e-154 512.4 0.1 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase Abhydrolase_3 PF07859.13 ORX94817.1 - 1.6e-48 165.4 0.0 3.8e-48 164.1 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 ORX94817.1 - 1.7e-05 23.9 0.0 6e-05 22.1 0.0 1.7 1 1 0 1 1 1 1 Carboxylesterase family Say1_Mug180 PF10340.9 ORX94817.1 - 0.00012 21.1 0.0 0.00017 20.6 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Chlorophyllase2 PF12740.7 ORX94817.1 - 0.00094 18.2 0.0 0.0013 17.7 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase enzyme Peptidase_S9 PF00326.21 ORX94817.1 - 0.0022 17.5 0.0 0.012 15.0 0.0 1.9 1 1 1 2 2 2 1 Prolyl oligopeptidase family Esterase PF00756.20 ORX94817.1 - 0.017 14.8 0.3 4.3 6.9 0.6 3.0 2 1 0 2 2 2 0 Putative esterase Fungal_trans PF04082.18 ORX94818.1 - 1e-19 70.6 0.1 1.5e-19 70.1 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 ORX94819.1 - 2e-42 145.4 26.5 2e-42 145.4 26.5 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORX94819.1 - 9.1e-09 34.7 10.5 9.1e-09 34.7 10.5 3.2 2 1 1 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.13 ORX94819.1 - 5.7e-07 28.4 3.3 9.4e-07 27.6 3.3 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Transp_cyt_pur PF02133.15 ORX94820.1 - 7.9e-34 117.2 33.4 1.2e-32 113.3 33.5 2.0 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Mito_carr PF00153.27 ORX94821.1 - 3.1e-54 180.9 1.7 7.2e-17 61.1 0.0 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein GFO_IDH_MocA PF01408.22 ORX94822.1 - 2.2e-17 64.0 0.1 3e-17 63.5 0.1 1.2 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 ORX94822.1 - 0.02 15.6 0.0 0.029 15.0 0.0 1.2 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Peptidase_M35 PF02102.15 ORX94823.1 - 7.9e-71 238.8 23.8 5.1e-65 219.7 21.0 2.0 1 1 1 2 2 2 2 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.6 ORX94823.1 - 1.8e-43 148.6 5.3 1.8e-43 148.6 5.3 1.6 2 0 0 2 2 2 1 Lysine-specific metallo-endopeptidase HRXXH PF13933.6 ORX94823.1 - 0.01 15.4 6.4 0.019 14.5 6.4 1.4 1 1 0 1 1 1 0 Putative peptidase family FAD_binding_3 PF01494.19 ORX94824.1 - 6.3e-17 61.9 0.0 6e-09 35.6 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Trp_halogenase PF04820.14 ORX94824.1 - 0.0041 16.0 0.1 0.074 11.9 0.1 2.1 2 0 0 2 2 2 1 Tryptophan halogenase NAD_binding_8 PF13450.6 ORX94824.1 - 0.018 15.3 1.0 0.039 14.2 1.0 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ORX94824.1 - 0.081 12.5 2.8 0.26 10.8 2.0 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase UPF0176_N PF17773.1 ORX94824.1 - 0.17 12.2 0.0 0.44 10.9 0.0 1.6 1 0 0 1 1 1 0 UPF0176 acylphosphatase like domain Bys1 PF04681.12 ORX94825.1 - 0.011 15.6 0.0 0.014 15.3 0.0 1.2 1 0 0 1 1 1 0 Blastomyces yeast-phase-specific protein Methyltransf_31 PF13847.6 ORX94826.1 - 2.3e-05 24.2 0.0 8.6e-05 22.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORX94826.1 - 0.0016 18.3 0.0 0.0023 17.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORX94826.1 - 0.0063 17.2 0.0 0.017 15.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Abhydrolase_1 PF00561.20 ORX94827.1 - 2.7e-20 73.1 0.1 1.6e-19 70.5 0.1 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORX94827.1 - 8.1e-16 59.3 0.3 1e-15 58.9 0.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORX94827.1 - 9.9e-16 57.7 0.0 1.5e-15 57.1 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 ORX94827.1 - 2.8e-05 23.0 0.0 4.5e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Ndr family DUF1057 PF06342.12 ORX94827.1 - 0.00098 18.2 0.0 0.0014 17.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Esterase PF00756.20 ORX94827.1 - 0.0019 17.9 0.2 0.0033 17.1 0.2 1.4 1 0 0 1 1 1 1 Putative esterase Acyl_transf_1 PF00698.21 ORX94827.1 - 0.0025 17.4 0.0 0.0035 16.9 0.0 1.2 1 0 0 1 1 1 1 Acyl transferase domain DUF915 PF06028.11 ORX94827.1 - 0.0031 16.9 0.1 0.0049 16.2 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) PGAP1 PF07819.13 ORX94827.1 - 0.014 15.1 0.0 0.023 14.4 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein UPF0227 PF05728.12 ORX94827.1 - 0.032 14.2 0.0 0.048 13.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Abhydrolase_5 PF12695.7 ORX94827.1 - 0.041 13.6 0.0 0.16 11.8 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase family Peptidase_S37 PF05576.11 ORX94827.1 - 0.059 12.0 0.0 0.088 11.5 0.0 1.1 1 0 0 1 1 1 0 PS-10 peptidase S37 Abhydrolase_2 PF02230.16 ORX94827.1 - 0.066 13.0 0.0 0.31 10.8 0.0 1.9 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Abhydrolase_8 PF06259.12 ORX94827.1 - 0.077 12.6 0.1 0.27 10.8 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase Thioesterase PF00975.20 ORX94827.1 - 0.19 11.8 0.3 0.34 11.0 0.3 1.3 1 0 0 1 1 1 0 Thioesterase domain FAD_binding_3 PF01494.19 ORX94848.1 - 4e-20 72.4 0.0 1e-19 71.0 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain SE PF08491.10 ORX94848.1 - 0.0011 18.1 0.0 0.0026 16.9 0.0 1.5 2 0 0 2 2 2 1 Squalene epoxidase DAO PF01266.24 ORX94848.1 - 0.0022 17.6 0.1 0.19 11.3 0.1 2.1 1 1 0 2 2 2 1 FAD dependent oxidoreductase MHC_I PF00129.18 ORX94848.1 - 0.0077 15.8 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 1 Class I Histocompatibility antigen, domains alpha 1 and 2 NAD_binding_8 PF13450.6 ORX94848.1 - 0.015 15.5 0.1 0.033 14.4 0.1 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ORX94848.1 - 0.024 13.9 0.0 0.046 13.0 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 ORX94848.1 - 0.024 13.7 0.2 1.6 7.7 0.0 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_binding_2 PF00890.24 ORX94848.1 - 0.095 11.8 0.1 0.22 10.6 0.1 1.6 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 ORX94848.1 - 0.12 11.0 0.1 0.28 9.8 0.0 1.6 2 0 0 2 2 2 0 HI0933-like protein Glyco_hydro_12 PF01670.16 ORX94849.1 - 3.4e-16 59.9 7.7 6.1e-14 52.5 1.6 2.8 1 1 1 2 2 2 2 Glycosyl hydrolase family 12 Nnf1 PF03980.14 ORX94851.1 - 0.12 12.8 0.9 0.84 10.0 0.4 2.1 2 0 0 2 2 2 0 Nnf1 F-box-like PF12937.7 ORX94852.1 - 2.9e-05 23.9 0.0 9.2e-05 22.3 0.0 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORX94852.1 - 0.0016 18.3 0.0 0.014 15.3 0.0 2.4 2 0 0 2 2 2 1 F-box domain Adap_comp_sub PF00928.21 ORX94853.1 - 1.6e-15 57.2 0.0 2.3e-15 56.7 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 ORX94853.1 - 1.4e-07 31.5 0.3 2.2e-07 30.9 0.3 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain RPM2 PF08579.11 ORX94853.1 - 2.7e-05 24.6 1.8 0.0016 18.8 0.8 2.6 2 0 0 2 2 2 1 Mitochondrial ribonuclease P subunit (RPM2) Helo_like_N PF17111.5 ORX94879.1 - 0.0004 19.8 1.2 0.0008 18.8 1.2 1.5 1 1 0 1 1 1 1 Fungal N-terminal domain of STAND proteins BAR_3 PF16746.5 ORX94879.1 - 0.085 12.5 0.8 0.12 12.1 0.8 1.1 1 0 0 1 1 1 0 BAR domain of APPL family FAD_binding_1 PF00667.20 ORX94880.1 - 5.6e-61 205.9 0.0 1.1e-60 205.0 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 ORX94880.1 - 1.1e-10 42.1 0.0 3.2e-10 40.6 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain PFOR_II PF17147.4 ORX94880.1 - 8.3e-06 26.0 0.1 1.9e-05 24.9 0.1 1.7 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II POR PF01558.18 ORX94880.1 - 0.00075 19.6 0.0 0.0038 17.3 0.0 2.0 2 0 0 2 2 2 1 Pyruvate ferredoxin/flavodoxin oxidoreductase Transketolase_C PF02780.20 ORX94880.1 - 0.0087 15.9 0.1 0.033 14.1 0.1 1.9 1 0 0 1 1 1 1 Transketolase, C-terminal domain FAD_binding_6 PF00970.24 ORX94880.1 - 0.099 13.0 0.1 10 6.6 0.0 3.3 4 0 0 4 4 4 0 Oxidoreductase FAD-binding domain Late_protein_L2 PF00513.18 ORX94882.1 - 0.23 10.4 0.3 0.33 9.9 0.3 1.2 1 0 0 1 1 1 0 Late Protein L2 DUF1304 PF06993.12 ORX94882.1 - 0.43 10.6 6.9 0.91 9.5 6.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1304) FAD_binding_4 PF01565.23 ORX94884.1 - 8.6e-23 80.6 1.0 1.6e-22 79.8 1.0 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 ORX94884.1 - 2.1e-08 34.1 0.6 4.1e-08 33.2 0.6 1.5 1 0 0 1 1 1 1 Berberine and berberine like zf-C2H2 PF00096.26 ORX94885.1 - 1.8e-10 40.7 17.6 0.00024 21.4 2.5 4.1 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORX94885.1 - 8.2e-07 29.3 16.8 0.0078 17.0 2.1 3.9 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 ORX94885.1 - 0.014 15.3 8.9 3.7 7.7 0.0 3.8 3 0 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORX94885.1 - 0.023 15.1 0.5 0.023 15.1 0.5 4.2 4 0 0 4 4 4 0 Zinc-finger double domain Sina PF03145.16 ORX94885.1 - 0.26 11.2 7.6 0.19 11.7 2.2 2.0 1 1 1 2 2 2 0 Seven in absentia protein family zf-C2H2_2 PF12756.7 ORX94885.1 - 0.6 10.5 10.0 32 4.9 9.9 2.2 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2_aberr PF17017.5 ORX94885.1 - 0.92 9.6 6.3 1 9.5 4.3 1.9 1 1 1 2 2 2 0 Aberrant zinc-finger zf-Di19 PF05605.12 ORX94885.1 - 1.1 9.6 10.0 5.2 7.4 2.8 2.4 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding FOXP-CC PF16159.5 ORX94885.1 - 7 7.4 6.6 32 5.2 0.4 2.8 1 1 2 3 3 3 0 FOXP coiled-coil domain Fungal_trans PF04082.18 ORX94888.1 - 1e-19 70.6 0.1 1.5e-19 70.0 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORX94888.1 - 0.006 16.7 7.5 0.012 15.7 7.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Putative_PNPOx PF01243.20 ORX94889.1 - 5.5e-06 26.5 0.0 9.1e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Ank_5 PF13857.6 ORX94927.1 - 0.00021 21.5 2.2 0.01 16.1 0.2 3.6 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 ORX94927.1 - 0.00048 20.7 0.1 0.074 13.7 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ank PF00023.30 ORX94927.1 - 0.00051 20.4 0.7 0.36 11.4 0.0 4.0 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 ORX94927.1 - 0.012 16.2 0.5 8.5 7.1 0.1 4.2 3 1 1 4 4 4 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORX94927.1 - 0.014 15.9 0.2 7.3 7.5 0.0 4.8 5 0 0 5 5 5 0 Ankyrin repeat Helo_like_N PF17111.5 ORX94927.1 - 0.17 11.2 5.8 0.41 10.0 5.8 1.7 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins DUF948 PF06103.11 ORX94927.1 - 0.44 10.9 4.5 2.4 8.5 0.0 3.3 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) TolA_bind_tri PF16331.5 ORX94927.1 - 0.78 9.9 8.6 11 6.2 0.0 4.3 3 1 1 4 4 4 0 TolA binding protein trimerisation Abhydrolase_3 PF07859.13 ORX94928.1 - 8e-21 74.9 0.0 1.1e-20 74.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 ORX94928.1 - 9.2e-18 64.2 0.0 1.7e-17 63.4 0.0 1.3 1 1 0 1 1 1 1 Steryl acetyl hydrolase Hydrolase_4 PF12146.8 ORX94928.1 - 0.0046 16.3 0.0 0.0091 15.3 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 TCRP1 PF14944.6 ORX94928.1 - 0.058 13.3 0.3 0.1 12.5 0.3 1.4 1 0 0 1 1 1 0 Tongue Cancer Chemotherapy Resistant Protein 1 Esterase PF00756.20 ORX94928.1 - 0.097 12.3 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Putative esterase COesterase PF00135.28 ORX94929.1 - 4.8e-78 263.3 0.0 1.1e-68 232.4 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 ORX94929.1 - 0.00061 19.7 0.3 0.0024 17.8 0.3 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF2235 PF09994.9 ORX94931.1 - 5.4e-60 203.2 0.0 7.9e-60 202.6 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Palm_thioest PF02089.15 ORX94931.1 - 0.11 12.4 0.0 0.23 11.3 0.0 1.5 2 0 0 2 2 2 0 Palmitoyl protein thioesterase Asp PF00026.23 ORX94933.1 - 8.6e-12 45.1 0.4 1.2e-11 44.6 0.4 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 ORX94933.1 - 0.015 15.6 0.1 0.067 13.4 0.0 2.0 2 0 0 2 2 2 0 Xylanase inhibitor N-terminal TMEM154 PF15102.6 ORX94933.1 - 0.025 14.5 0.0 0.049 13.5 0.0 1.4 1 0 0 1 1 1 0 TMEM154 protein family LapA_dom PF06305.11 ORX94933.1 - 0.079 12.8 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Zn_clus PF00172.18 ORX94935.1 - 2.2e-07 30.9 9.3 3.9e-07 30.1 9.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NmrA PF05368.13 ORX94936.1 - 4e-38 131.3 0.0 5.1e-38 130.9 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ORX94936.1 - 4.4e-21 75.6 0.1 1.1e-20 74.3 0.0 1.7 2 0 0 2 2 2 1 NAD(P)H-binding SH3_7 PF12914.7 ORX94936.1 - 0.026 14.7 0.0 0.052 13.7 0.0 1.5 1 0 0 1 1 1 0 SH3 domain of SH3b2 type Phage_head_chap PF11113.8 ORX94936.1 - 0.034 14.2 0.0 6.8 6.9 0.0 2.3 2 0 0 2 2 2 0 Head assembly gene product Mur_ligase PF01225.25 ORX94936.1 - 0.046 14.0 0.0 0.14 12.5 0.0 1.8 1 1 0 1 1 1 0 Mur ligase family, catalytic domain Epimerase PF01370.21 ORX94936.1 - 0.052 13.0 0.3 0.18 11.2 0.1 2.1 3 0 0 3 3 3 0 NAD dependent epimerase/dehydratase family Tyrosinase PF00264.20 ORX94962.1 - 1.9e-45 155.8 0.8 3.4e-45 155.0 0.8 1.4 1 0 0 1 1 1 1 Common central domain of tyrosinase Tyosinase_C PF18132.1 ORX94962.1 - 4.5e-15 56.4 0.0 7.4e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 Tyosinase C-terminal domain DUF4834 PF16118.5 ORX94994.1 - 2.6 9.1 4.3 4.1 8.4 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) LigB PF02900.18 ORX94996.1 - 1.8e-19 69.9 0.0 2.1e-19 69.7 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase RR_TM4-6 PF06459.12 ORX94997.1 - 3.6 7.3 9.4 4.5 7.0 9.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 OMPdecase PF00215.24 ORX94998.1 - 1.1e-77 260.7 0.0 1.2e-77 260.5 0.0 1.0 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family DUF3246 PF11596.8 ORX94998.1 - 0.018 14.5 2.8 0.028 13.9 2.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) BetaGal_dom3 PF13363.6 ORX94998.1 - 0.035 13.7 0.0 0.071 12.7 0.0 1.4 1 0 0 1 1 1 0 Beta-galactosidase, domain 3 DUF4611 PF15387.6 ORX94998.1 - 0.043 14.0 0.1 0.082 13.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Cu-oxidase_2 PF07731.14 ORX94999.1 - 3e-49 166.3 4.3 5.6e-42 142.7 0.1 3.5 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 ORX94999.1 - 4.3e-46 155.8 5.9 3.4e-42 143.2 0.9 3.9 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 ORX94999.1 - 7.3e-41 139.9 1.7 1.2e-32 113.2 0.1 3.2 3 0 0 3 3 3 3 Multicopper oxidase Cupredoxin_1 PF13473.6 ORX94999.1 - 6.9e-06 26.1 0.0 0.25 11.5 0.0 4.0 3 2 0 3 3 3 2 Cupredoxin-like domain FTR1 PF03239.14 ORX95000.1 - 3.5e-84 282.6 5.3 4.1e-84 282.4 5.3 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family Rft-1 PF04506.13 ORX95000.1 - 0.017 13.9 0.1 0.026 13.3 0.1 1.2 1 0 0 1 1 1 0 Rft protein B12D PF06522.11 ORX95000.1 - 0.14 12.0 2.0 1.5 8.7 0.4 2.7 2 0 0 2 2 2 0 NADH-ubiquinone reductase complex 1 MLRQ subunit ABC2_membrane_5 PF13346.6 ORX95000.1 - 0.51 9.8 9.2 0.088 12.4 0.3 2.8 2 1 0 2 2 2 0 ABC-2 family transporter protein PNK3P PF08645.11 ORX95001.1 - 9e-44 149.0 0.0 1.2e-43 148.6 0.0 1.2 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.6 ORX95001.1 - 3e-11 43.7 0.1 3.5e-05 24.0 0.0 2.6 2 1 1 3 3 3 2 AAA domain KTI12 PF08433.10 ORX95001.1 - 0.21 11.0 0.0 16 4.9 0.0 2.1 1 1 1 2 2 2 0 Chromatin associated protein KTI12 VWA PF00092.28 ORX95003.1 - 8.7e-08 32.6 0.0 1.2e-07 32.1 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 ORX95003.1 - 2.1e-05 25.1 0.0 4e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain Helo_like_N PF17111.5 ORX95004.1 - 5.3e-09 35.8 2.2 5.8e-07 29.1 0.7 2.3 2 0 0 2 2 2 2 Fungal N-terminal domain of STAND proteins DUF1664 PF07889.12 ORX95004.1 - 0.00095 19.2 1.2 0.16 12.0 0.3 2.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1664) NPV_P10 PF05531.12 ORX95004.1 - 0.012 16.0 3.1 0.92 10.0 0.0 3.4 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein CENP-F_leu_zip PF10473.9 ORX95004.1 - 0.012 15.6 3.4 0.95 9.5 0.1 3.0 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Laminin_II PF06009.12 ORX95004.1 - 0.054 13.5 2.9 5.9 6.9 0.2 2.7 2 0 0 2 2 2 0 Laminin Domain II DASH_Dam1 PF08653.10 ORX95004.1 - 0.057 13.2 0.1 0.43 10.4 0.1 2.6 2 0 0 2 2 2 0 DASH complex subunit Dam1 BLOC1_2 PF10046.9 ORX95004.1 - 0.062 13.6 1.1 1.4 9.3 0.1 3.2 3 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 WXG100 PF06013.12 ORX95004.1 - 0.25 11.6 2.9 10 6.4 0.0 3.4 3 0 0 3 3 3 0 Proteins of 100 residues with WXG Vps51 PF08700.11 ORX95004.1 - 2.4 8.3 6.5 3.3 7.8 0.1 3.1 3 0 0 3 3 3 0 Vps51/Vps67 Pyr_redox_3 PF13738.6 ORX95005.1 - 1.4e-18 67.2 0.0 1.4e-17 63.9 0.0 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 ORX95005.1 - 2.4e-14 52.7 0.0 1.1e-07 30.7 0.0 3.1 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 ORX95005.1 - 5.6e-13 48.8 0.0 5e-10 39.1 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ORX95005.1 - 4.8e-06 25.9 0.0 0.00013 21.3 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.12 ORX95005.1 - 7.3e-05 22.0 0.0 0.00071 18.7 0.0 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.17 ORX95005.1 - 0.00011 21.5 0.0 0.00066 19.0 0.0 2.0 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 ORX95005.1 - 0.00014 21.5 0.0 0.085 12.4 0.0 2.9 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 ORX95005.1 - 0.00023 21.2 0.1 0.19 11.7 0.0 3.2 2 1 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 ORX95005.1 - 0.0018 18.8 0.1 1.1 9.9 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 ORX95005.1 - 0.018 14.1 0.2 4.4 6.3 0.0 2.9 3 0 0 3 3 3 0 Glucose inhibited division protein A FAD_oxidored PF12831.7 ORX95005.1 - 0.026 13.9 0.0 0.041 13.2 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ORX95005.1 - 0.041 14.1 0.1 0.41 10.9 0.0 2.5 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 ORX95005.1 - 0.13 11.5 0.0 0.27 10.5 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain SnoaL PF07366.12 ORX95006.1 - 1.6e-05 24.7 0.0 2.9e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 ORX95006.1 - 0.00078 20.1 0.0 0.0027 18.3 0.0 1.9 1 1 1 2 2 2 1 SnoaL-like domain DLH PF01738.18 ORX95006.1 - 0.016 14.8 0.0 0.033 13.7 0.0 1.7 1 1 0 1 1 1 0 Dienelactone hydrolase family DUF1257 PF06868.11 ORX95006.1 - 0.017 15.3 0.0 0.034 14.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1257) F-box-like PF12937.7 ORX95007.1 - 0.0058 16.5 1.4 0.034 14.0 0.0 2.7 2 1 1 3 3 3 1 F-box-like F-box PF00646.33 ORX95007.1 - 0.056 13.3 0.4 0.96 9.4 0.1 2.7 2 1 0 2 2 2 0 F-box domain SRP19 PF01922.17 ORX95009.1 - 8.5e-35 119.6 0.0 1.3e-34 119.0 0.0 1.3 1 0 0 1 1 1 1 SRP19 protein Aminotran_3 PF00202.21 ORX95010.1 - 2.7e-85 286.5 0.1 3.1e-85 286.3 0.1 1.1 1 0 0 1 1 1 1 Aminotransferase class-III CorA PF01544.18 ORX95036.1 - 0.00039 19.8 2.0 0.00099 18.5 2.0 1.7 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Tim17 PF02466.19 ORX95038.1 - 1.2e-32 112.5 8.9 1.6e-32 112.2 8.9 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Phage_holin_3_3 PF16083.5 ORX95038.1 - 0.065 13.4 8.0 0.052 13.7 2.1 2.3 2 0 0 2 2 2 0 LydA holin phage, holin superfamily III PsaL PF02605.15 ORX95038.1 - 1.9 8.1 4.9 27 4.4 2.0 2.2 2 0 0 2 2 2 0 Photosystem I reaction centre subunit XI RTC PF01137.21 ORX95039.1 - 1.3e-62 210.9 0.0 1.7e-62 210.5 0.0 1.1 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase adh_short_C2 PF13561.6 ORX95040.1 - 3.3e-57 193.7 9.8 9.2e-31 107.2 0.9 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORX95040.1 - 4.9e-47 159.9 2.4 1.5e-27 96.3 0.4 2.0 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 ORX95040.1 - 4.8e-09 36.4 0.8 8.2e-09 35.6 0.7 1.5 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 ORX95040.1 - 0.0068 15.6 0.1 0.0092 15.1 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein SUV3_C PF12513.8 ORX95040.1 - 0.41 10.6 0.7 0.66 10.0 0.0 1.7 2 0 0 2 2 2 0 Mitochondrial degradasome RNA helicase subunit C terminal FSH1 PF03959.13 ORX95041.1 - 6.5e-20 71.7 0.0 8.9e-20 71.3 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) MFS_1 PF07690.16 ORX95042.1 - 1.5e-33 116.2 52.8 1.2e-30 106.7 52.8 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORX95042.1 - 5.9e-09 35.3 14.3 5.9e-09 35.3 14.3 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter YrhK PF14145.6 ORX95042.1 - 0.033 14.1 1.3 0.033 14.1 1.3 3.1 2 1 1 3 3 3 0 YrhK-like protein DUF5592 PF17332.2 ORX95043.1 - 8.5 7.0 7.7 4.7 7.8 0.0 2.8 3 1 0 3 3 3 0 Family of unknown function (DUF5592) ketoacyl-synt PF00109.26 ORX95044.1 - 6.3e-69 232.4 0.1 1.4e-68 231.3 0.1 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 ORX95044.1 - 5.7e-60 202.3 0.3 1.5e-59 201.0 0.3 1.8 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 ORX95044.1 - 7.9e-52 176.3 0.2 1.4e-51 175.5 0.2 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 ORX95044.1 - 1.6e-47 162.6 0.0 4.5e-47 161.1 0.0 1.8 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 ORX95044.1 - 3.6e-22 78.6 0.0 4.2e-13 49.4 0.0 3.0 1 1 1 2 2 2 2 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 ORX95044.1 - 1.2e-16 61.2 0.0 3.1e-16 59.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.6 ORX95044.1 - 1.7e-14 55.0 0.0 1.3e-13 52.1 0.0 2.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase KAsynt_C_assoc PF16197.5 ORX95044.1 - 1.1e-13 51.6 0.0 3e-13 50.2 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N PF00107.26 ORX95044.1 - 1.2e-10 41.5 0.0 4.7e-10 39.5 0.0 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 ORX95044.1 - 3.3e-10 39.7 0.1 8.7e-10 38.4 0.1 1.7 1 0 0 1 1 1 1 short chain dehydrogenase PP-binding PF00550.25 ORX95044.1 - 4.9e-10 39.6 0.0 5.4e-09 36.3 0.0 2.8 3 0 0 3 3 2 1 Phosphopantetheine attachment site Methyltransf_25 PF13649.6 ORX95044.1 - 2.7e-09 37.6 0.0 1.2e-08 35.5 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORX95044.1 - 1.3e-08 34.8 0.0 4.1e-08 33.1 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORX95044.1 - 2.1e-08 34.2 0.0 6.8e-08 32.5 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORX95044.1 - 1.2e-06 29.0 0.0 7e-06 26.6 0.0 2.4 2 0 0 2 2 1 1 Methyltransferase domain adh_short_C2 PF13561.6 ORX95044.1 - 3.6e-06 26.7 0.0 1e-05 25.3 0.0 1.8 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ADH_N PF08240.12 ORX95044.1 - 6.1e-06 26.1 0.0 1.4e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Ubie_methyltran PF01209.18 ORX95044.1 - 7.7e-06 25.4 0.0 1.7e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Thiolase_N PF00108.23 ORX95044.1 - 0.00089 18.7 0.1 0.0019 17.6 0.1 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain NAS PF03059.16 ORX95044.1 - 0.012 15.0 0.0 0.03 13.7 0.0 1.6 1 0 0 1 1 1 0 Nicotianamine synthase protein Methyltransf_16 PF10294.9 ORX95044.1 - 0.051 13.3 0.0 0.14 11.9 0.0 1.7 1 0 0 1 1 1 0 Lysine methyltransferase ACP_syn_III PF08545.10 ORX95044.1 - 0.21 11.5 0.7 0.81 9.6 0.7 2.1 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ABC_membrane PF00664.23 ORX95045.1 - 2.7e-50 171.6 8.1 3.4e-50 171.2 8.1 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 ORX95045.1 - 5e-34 117.7 0.0 1.3e-33 116.4 0.0 1.7 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 ORX95045.1 - 0.00017 21.1 0.0 0.00032 20.2 0.0 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 ORX95045.1 - 0.0041 17.4 0.1 0.038 14.3 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 ORX95045.1 - 0.006 16.3 0.2 0.017 14.9 0.2 1.7 1 1 0 1 1 1 1 AAA domain DUF3987 PF13148.6 ORX95045.1 - 0.037 13.0 0.0 0.072 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) AAA_16 PF13191.6 ORX95045.1 - 0.037 14.4 0.1 0.096 13.1 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 ORX95045.1 - 0.039 14.4 0.1 0.24 11.8 0.1 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.6 ORX95045.1 - 0.12 12.7 0.8 1.5 9.1 0.8 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Cupin_2 PF07883.11 ORX95046.1 - 2.9e-15 55.7 0.6 5.1e-15 55.0 0.6 1.4 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 ORX95046.1 - 2.1e-05 24.4 0.0 2.9e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain ARD PF03079.14 ORX95046.1 - 3.4e-05 24.1 0.4 7.1e-05 23.0 0.0 1.7 1 1 1 2 2 2 1 ARD/ARD' family Cupin_6 PF12852.7 ORX95046.1 - 0.00022 21.0 0.1 0.00025 20.8 0.1 1.1 1 0 0 1 1 1 1 Cupin Cupin_1 PF00190.22 ORX95046.1 - 0.00031 20.4 0.1 0.0004 20.0 0.1 1.2 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.12 ORX95046.1 - 0.0014 18.3 0.3 0.0028 17.3 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF861) MannoseP_isomer PF01050.18 ORX95046.1 - 0.045 13.6 0.0 0.063 13.2 0.0 1.2 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase FAD_binding_1 PF00667.20 ORX95047.1 - 4.1e-49 167.1 0.0 5.8e-49 166.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 ORX95047.1 - 2e-10 41.3 0.0 4e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain TraG-D_C PF12696.7 ORX95047.1 - 0.17 11.9 0.0 1.7 8.6 0.0 2.5 3 0 0 3 3 3 0 TraM recognition site of TraD and TraG WD40 PF00400.32 ORX95048.1 - 4.6e-24 84.2 11.8 4.3e-09 36.9 0.0 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX95048.1 - 1.4e-09 38.2 0.5 0.0016 18.7 0.0 3.7 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 ORX95048.1 - 2e-05 23.7 0.1 0.05 12.5 0.0 3.1 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 ORX95048.1 - 0.00038 19.3 2.9 0.6 8.7 1.7 2.7 2 1 0 2 2 2 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 ORX95048.1 - 0.09 11.5 0.5 5.9 5.5 0.0 2.5 2 1 0 2 2 2 0 Nup133 N terminal like Me-amine-dh_H PF06433.11 ORX95048.1 - 0.091 11.6 0.0 0.3 9.9 0.0 1.8 2 1 0 2 2 2 0 Methylamine dehydrogenase heavy chain (MADH) UL73_N PF12522.8 ORX95048.1 - 4 7.3 13.5 13 5.6 8.7 2.9 2 0 0 2 2 2 0 Cytomegalovirus glycoprotein N terminal Metallophos PF00149.28 ORX95050.1 - 2.2e-10 41.4 1.5 3.3e-10 40.8 1.5 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PA_decarbox PF05870.11 ORX95066.1 - 4.2e-07 29.7 0.1 5.3e-07 29.4 0.1 1.2 1 0 0 1 1 1 1 Phenolic acid decarboxylase (PAD) Helo_like_N PF17111.5 ORX95072.1 - 2e-87 292.0 6.6 2e-82 275.6 2.1 2.1 2 0 0 2 2 2 2 Fungal N-terminal domain of STAND proteins SesA PF17107.5 ORX95072.1 - 8e-05 22.8 1.4 0.00048 20.3 0.0 2.4 2 1 0 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases Prominin PF05478.11 ORX95072.1 - 0.046 11.7 1.3 0.077 10.9 0.7 1.6 2 0 0 2 2 2 0 Prominin DUF4037 PF13228.6 ORX95072.1 - 0.056 14.3 0.1 0.21 12.4 0.1 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4037) KxDL PF10241.9 ORX95072.1 - 0.084 13.2 1.4 3.6 7.9 0.0 3.5 3 1 0 3 3 3 0 Uncharacterized conserved protein NPV_P10 PF05531.12 ORX95072.1 - 0.13 12.7 0.4 6.3 7.3 0.1 2.8 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein PMEI PF04043.15 ORX95072.1 - 0.16 12.3 10.8 3.3 8.0 7.1 3.1 1 1 1 2 2 2 0 Plant invertase/pectin methylesterase inhibitor PRESAN PF09687.10 ORX95072.1 - 0.16 12.5 0.0 0.55 10.8 0.0 1.9 2 0 0 2 2 2 0 Plasmodium RESA N-terminal Spectrin PF00435.21 ORX95072.1 - 0.39 11.2 4.4 17 5.9 0.0 3.3 2 1 1 3 3 3 0 Spectrin repeat AAA PF00004.29 ORX95073.1 - 0.00011 22.6 0.1 0.00012 22.5 0.1 1.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Spy1 PF11357.8 ORX95073.1 - 0.03 14.6 0.1 0.033 14.5 0.1 1.1 1 0 0 1 1 1 0 Cell cycle regulatory protein MerR-DNA-bind PF09278.11 ORX95074.1 - 0.081 13.5 0.0 0.11 13.0 0.0 1.2 1 1 0 1 1 1 0 MerR, DNA binding Fer4_24 PF18109.1 ORX95074.1 - 0.27 11.5 1.1 0.33 11.3 0.0 1.7 3 0 0 3 3 3 0 Ferredoxin I 4Fe-4S cluster domain GNAT_acetyltr_2 PF13718.6 ORX95075.1 - 0.067 12.6 2.9 0.11 11.9 2.9 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase 2 HSDR_N_2 PF13588.6 ORX95075.1 - 0.074 13.0 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 Type I restriction enzyme R protein N terminus (HSDR_N) DUF913 PF06025.12 ORX95075.1 - 0.4 9.6 5.3 0.68 8.8 5.3 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DDRGK PF09756.9 ORX95075.1 - 0.42 10.2 18.4 0.62 9.6 18.4 1.2 1 0 0 1 1 1 0 DDRGK domain Borrelia_P83 PF05262.11 ORX95075.1 - 1.1 7.7 9.4 1.6 7.2 9.4 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Afi1 PF07792.12 ORX95075.1 - 1.9 9.0 7.7 4.2 7.9 7.7 1.6 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking CDC45 PF02724.14 ORX95075.1 - 1.9 6.7 11.8 3.1 6.0 11.8 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF2058 PF09831.9 ORX95075.1 - 2.2 8.4 12.3 3.5 7.8 12.3 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) CCDC53 PF10152.9 ORX95075.1 - 3 8.2 10.2 2.5 8.5 4.1 2.6 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Connexin PF00029.19 ORX95075.1 - 3.9 7.2 6.9 6.7 6.4 6.9 1.3 1 0 0 1 1 1 0 Connexin Cdh1_DBD_1 PF18196.1 ORX95075.1 - 5.2 7.4 12.1 11 6.4 12.1 1.5 1 0 0 1 1 1 0 Chromodomain helicase DNA-binding domain 1 DBINO PF13892.6 ORX95076.1 - 0.62 10.4 5.7 1.4 9.3 5.7 1.6 1 1 0 1 1 1 0 DNA-binding domain Pkinase PF00069.25 ORX95097.1 - 6.9e-66 222.3 0.0 1.1e-65 221.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX95097.1 - 9.2e-33 113.6 0.0 6.6e-32 110.8 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 ORX95097.1 - 0.00058 19.3 0.0 0.001 18.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 ORX95097.1 - 0.0028 16.7 0.0 0.0042 16.1 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 ORX95097.1 - 0.0033 17.1 0.1 0.6 9.7 0.0 2.3 1 1 1 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 ORX95097.1 - 0.0045 16.3 0.3 0.023 14.0 0.0 2.2 2 1 0 2 2 2 1 Kinase-like APH PF01636.23 ORX95097.1 - 0.0076 16.2 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Aldose_epim PF01263.20 ORX95099.1 - 6.2e-44 150.5 0.3 7.7e-44 150.2 0.3 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase FAM183 PF14886.6 ORX95100.1 - 0.043 14.5 2.0 0.27 12.0 0.1 3.4 3 0 0 3 3 3 0 FAM183A and FAM183B related CHCH PF06747.13 ORX95101.1 - 0.092 12.9 0.3 0.13 12.5 0.3 1.2 1 0 0 1 1 1 0 CHCH domain BatD PF13584.6 ORX95102.1 - 0.0067 15.3 0.0 0.0094 14.8 0.0 1.1 1 0 0 1 1 1 1 Oxygen tolerance DUF456 PF04306.13 ORX95102.1 - 0.02 15.2 0.2 0.035 14.4 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF456) TrbL PF04610.14 ORX95102.1 - 0.046 13.5 2.8 0.068 12.9 2.8 1.2 1 0 0 1 1 1 0 TrbL/VirB6 plasmid conjugal transfer protein RIFIN PF02009.16 ORX95102.1 - 0.13 12.1 0.0 0.17 11.8 0.0 1.1 1 0 0 1 1 1 0 Rifin EphA2_TM PF14575.6 ORX95102.1 - 0.17 12.8 0.0 0.32 11.9 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Syndecan PF01034.20 ORX95103.1 - 0.18 11.8 0.0 0.33 10.9 0.0 1.3 1 0 0 1 1 1 0 Syndecan domain GCFC PF07842.12 ORX95104.1 - 1.3e-27 97.1 6.4 1.8e-27 96.7 6.4 1.2 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.23 ORX95104.1 - 1.4e-13 50.5 2.2 1.4e-13 50.5 2.2 1.9 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 ORX95104.1 - 6.6e-06 26.1 0.5 2.1e-05 24.5 0.5 1.9 1 0 0 1 1 1 1 G-patch domain UCR_hinge PF02320.16 ORX95106.1 - 1.2e-26 92.7 9.0 1.8e-26 92.1 9.0 1.3 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein Tmemb_cc2 PF10267.9 ORX95106.1 - 0.12 11.5 0.2 0.14 11.3 0.2 1.0 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Raftlin PF15250.6 ORX95106.1 - 1.3 7.7 5.5 1.4 7.6 5.5 1.0 1 0 0 1 1 1 0 Raftlin Sporozoite_P67 PF05642.11 ORX95106.1 - 1.7 6.6 7.5 1.8 6.5 7.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CDC45 PF02724.14 ORX95106.1 - 4.5 5.4 5.9 4.6 5.4 5.9 1.0 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 ORX95106.1 - 6.8 4.8 12.0 7.2 4.7 12.0 1.0 1 0 0 1 1 1 0 Nop14-like family MFS_1 PF07690.16 ORX95107.1 - 2.5e-22 79.3 37.4 3.4e-22 78.9 37.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Peptidase_M41 PF01434.18 ORX95108.1 - 1.3e-51 175.2 0.1 2.1e-51 174.5 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 ORX95108.1 - 2.2e-43 147.8 0.0 4.1e-43 147.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 ORX95108.1 - 3.8e-08 33.0 0.0 7e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 ORX95108.1 - 1.9e-06 27.9 0.1 9.1e-06 25.7 0.0 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 ORX95108.1 - 1.4e-05 24.5 0.0 5.1e-05 22.6 0.0 1.8 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_22 PF13401.6 ORX95108.1 - 6.3e-05 23.3 0.1 0.062 13.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 ORX95108.1 - 0.0001 22.8 0.2 0.0012 19.3 0.2 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 ORX95108.1 - 0.00022 20.8 0.6 0.17 11.4 0.1 2.3 1 1 1 2 2 2 2 AAA domain RuvB_N PF05496.12 ORX95108.1 - 0.00022 21.0 0.0 0.00064 19.5 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 ORX95108.1 - 0.007 16.5 0.0 0.018 15.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 ORX95108.1 - 0.013 15.2 0.0 0.024 14.4 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_2 PF07724.14 ORX95108.1 - 0.019 15.1 0.0 0.042 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) ATPase PF06745.13 ORX95108.1 - 0.022 14.1 0.0 1.1 8.6 0.0 2.3 2 0 0 2 2 2 0 KaiC Mg_chelatase PF01078.21 ORX95108.1 - 0.023 14.1 0.2 0.052 12.9 0.2 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 ORX95108.1 - 0.1 12.6 0.0 0.23 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 ORX95108.1 - 0.12 12.6 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 ORX95108.1 - 0.13 12.8 0.0 0.31 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 ORX95108.1 - 0.18 11.3 0.1 0.5 9.9 0.1 1.8 1 1 0 1 1 1 0 P-loop containing dynein motor region UCH_1 PF13423.6 ORX95109.1 - 6.1e-88 295.5 5.6 9.7e-87 291.5 4.2 2.5 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.24 ORX95109.1 - 6.1e-21 75.7 0.0 1.4e-20 74.4 0.0 1.7 2 0 0 2 2 2 1 Exonuclease DUF4945 PF16303.5 ORX95109.1 - 0.071 13.0 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4945) Ima1_N PF09779.9 ORX95109.1 - 0.079 13.8 0.6 0.18 12.6 0.6 1.5 1 0 0 1 1 1 0 Ima1 N-terminal domain Rx_N PF18052.1 ORX95110.1 - 0.00011 22.4 0.3 0.00019 21.6 0.3 1.4 1 0 0 1 1 1 1 Rx N-terminal domain Tudor-knot PF11717.8 ORX95110.1 - 0.01 15.7 0.0 0.025 14.5 0.0 1.6 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain Agenet PF05641.12 ORX95110.1 - 0.011 16.2 0.0 0.022 15.2 0.0 1.6 1 0 0 1 1 1 0 Agenet domain Spc7 PF08317.11 ORX95110.1 - 0.21 10.4 1.8 0.31 9.9 1.8 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein HR1 PF02185.16 ORX95110.1 - 1.3 9.2 4.7 2.1 8.5 0.4 2.6 2 1 1 3 3 3 0 Hr1 repeat PAP1 PF08601.10 ORX95130.1 - 7.4e-125 417.5 19.9 8.2e-125 417.4 19.9 1.0 1 0 0 1 1 1 1 Transcription factor PAP1 SPX PF03105.19 ORX95130.1 - 4 7.2 14.6 5.6 6.8 14.6 1.2 1 0 0 1 1 1 0 SPX domain Fringe PF02434.16 ORX95131.1 - 8.9e-11 41.7 0.0 1.7e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 Fringe-like PAN_4 PF14295.6 ORX95131.1 - 0.0068 16.3 3.5 0.0089 15.9 2.1 1.9 2 0 0 2 2 2 1 PAN domain Galactosyl_T PF01762.21 ORX95131.1 - 0.0098 15.7 0.0 0.05 13.4 0.0 2.0 1 1 0 1 1 1 1 Galactosyltransferase PAN_3 PF08277.12 ORX95131.1 - 0.11 12.3 1.2 0.21 11.4 0.4 1.8 2 0 0 2 2 2 0 PAN-like domain NUP PF06516.11 ORX95132.1 - 5.7e-31 107.9 0.0 1.6e-13 50.6 0.0 3.0 1 1 2 3 3 3 3 Purine nucleoside permease (NUP) p450 PF00067.22 ORX95133.1 - 9.2e-51 173.0 0.0 1.2e-50 172.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Thg1 PF04446.12 ORX95135.1 - 4.9e-36 123.5 0.2 8.2e-36 122.8 0.2 1.4 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Ribosomal_L6 PF00347.23 ORX95137.1 - 1.8e-21 76.6 0.0 1.2e-11 45.1 0.0 2.8 2 1 0 2 2 2 2 Ribosomal protein L6 Tht1 PF04163.12 ORX95138.1 - 7.9e-05 21.6 5.5 0.00016 20.6 1.2 2.7 1 1 0 1 1 1 1 Tht1-like nuclear fusion protein Mod_r PF07200.13 ORX95138.1 - 0.013 15.6 1.2 0.013 15.6 1.2 2.6 2 1 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein ATG16 PF08614.11 ORX95138.1 - 0.029 14.6 7.1 0.054 13.7 7.1 1.4 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) BRI3BP PF14965.6 ORX95138.1 - 0.055 13.0 0.1 0.12 11.9 0.1 1.6 1 0 0 1 1 1 0 Negative regulator of p53/TP53 GAS PF13851.6 ORX95138.1 - 0.15 11.4 10.7 2.5 7.4 5.4 2.5 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF5082 PF16888.5 ORX95138.1 - 0.21 11.9 4.6 0.49 10.7 4.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) Med21 PF11221.8 ORX95138.1 - 0.21 11.8 6.1 0.093 13.0 3.3 1.9 1 1 1 2 2 2 0 Subunit 21 of Mediator complex DUF948 PF06103.11 ORX95138.1 - 0.23 11.7 7.8 0.75 10.1 1.4 3.4 3 2 2 5 5 4 0 Bacterial protein of unknown function (DUF948) SKA2 PF16740.5 ORX95138.1 - 1.5 8.6 10.0 0.15 11.8 2.9 3.0 3 2 0 3 3 3 0 Spindle and kinetochore-associated protein 2 DUF4618 PF15397.6 ORX95138.1 - 1.6 8.1 11.7 2.1 7.7 3.8 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4618) HIP1_clath_bdg PF16515.5 ORX95138.1 - 1.7 9.3 13.1 0.36 11.5 3.3 2.9 1 1 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 MCPsignal PF00015.21 ORX95138.1 - 2.1 8.1 9.9 1.5 8.6 2.9 2.4 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF1759 PF03564.15 ORX95138.1 - 3.2 7.7 6.2 17 5.4 0.6 3.3 3 1 1 4 4 4 0 Protein of unknown function (DUF1759) PRKG1_interact PF15898.5 ORX95138.1 - 5.4 8.0 6.5 1.4 9.9 1.8 2.3 2 1 0 2 2 2 0 cGMP-dependent protein kinase interacting domain YabA PF06156.13 ORX95138.1 - 8.8 7.0 6.1 16 6.2 1.0 2.8 1 1 1 2 2 2 0 Initiation control protein YabA zf-C3HC PF07967.13 ORX95139.1 - 9.8e-35 119.5 0.0 1.9e-27 95.9 0.0 2.3 2 0 0 2 2 2 2 C3HC zinc finger-like Rsm1 PF08600.10 ORX95139.1 - 1.3e-22 79.8 0.1 3.7e-22 78.3 0.1 1.9 1 0 0 1 1 1 1 Rsm1-like DUF5129 PF17173.4 ORX95139.1 - 0.01 15.0 0.1 0.036 13.2 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5129) Inositol_P PF00459.25 ORX95140.1 - 9.7e-51 172.9 0.3 4.1e-50 170.8 0.3 1.7 1 1 0 1 1 1 1 Inositol monophosphatase family SLAC1 PF03595.17 ORX95141.1 - 8.2e-81 271.8 56.8 9.3e-81 271.6 56.8 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel ZZ PF00569.17 ORX95144.1 - 1 9.2 8.1 0.16 11.8 3.6 1.8 2 0 0 2 2 2 0 Zinc finger, ZZ type SurE PF01975.17 ORX95145.1 - 8.7e-31 107.2 1.4 1.2e-30 106.8 1.4 1.1 1 0 0 1 1 1 1 Survival protein SurE DHDPS PF00701.22 ORX95146.1 - 1.6e-18 66.5 0.1 3.8e-18 65.2 0.0 1.5 2 0 0 2 2 2 1 Dihydrodipicolinate synthetase family TauD PF02668.16 ORX95147.1 - 1.1e-14 54.9 2.9 2.8e-10 40.5 0.1 2.6 1 1 1 2 2 2 2 Taurine catabolism dioxygenase TauD, TfdA family FMO-like PF00743.19 ORX95149.1 - 2e-11 43.1 0.4 1.6e-10 40.0 0.1 2.4 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 ORX95149.1 - 2e-10 40.8 0.0 4.7e-10 39.5 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 ORX95149.1 - 0.00066 18.9 0.1 0.0028 16.8 0.0 2.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 ORX95149.1 - 0.0013 18.0 0.0 0.084 12.1 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ORX95149.1 - 0.0029 16.9 0.0 0.013 14.7 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ORX95149.1 - 0.12 12.3 0.0 3.8 7.5 0.0 3.0 3 0 0 3 3 3 0 FAD-NAD(P)-binding DUF572 PF04502.13 ORX95150.1 - 0.13 11.9 1.1 0.75 9.3 1.1 1.9 1 1 0 1 1 1 0 Family of unknown function (DUF572) TPR_12 PF13424.6 ORX95173.1 - 1.7e-75 249.3 40.4 9.7e-19 67.4 3.6 4.9 1 1 5 6 6 6 6 Tetratricopeptide repeat TPR_10 PF13374.6 ORX95173.1 - 2.5e-58 192.5 18.6 2.8e-12 46.1 0.2 6.6 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_1 PF00515.28 ORX95173.1 - 2.1e-21 74.8 18.6 5e-05 22.9 1.0 6.3 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_7 PF13176.6 ORX95173.1 - 5e-19 66.9 14.9 0.00013 21.8 0.0 6.6 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.6 ORX95173.1 - 6.6e-15 54.0 15.7 0.027 14.7 0.1 6.5 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_MalT PF17874.1 ORX95173.1 - 1.1e-14 54.6 6.9 1.8e-08 34.2 0.6 2.3 1 1 1 2 2 2 2 MalT-like TPR region TPR_14 PF13428.6 ORX95173.1 - 5.3e-12 45.5 11.6 0.06 14.2 0.1 6.2 3 1 2 5 5 5 4 Tetratricopeptide repeat NB-ARC PF00931.22 ORX95173.1 - 1.3e-11 44.2 0.0 1.9e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain TPR_17 PF13431.6 ORX95173.1 - 1.2e-10 41.0 10.3 0.18 12.2 0.1 7.1 6 2 0 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 ORX95173.1 - 1.9e-10 40.0 24.3 0.00085 19.3 1.6 6.4 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.6 ORX95173.1 - 5.9e-10 39.6 13.5 7.6e-05 23.3 2.5 4.3 2 1 2 4 4 3 3 Tetratricopeptide repeat TPR_4 PF07721.14 ORX95173.1 - 9.4e-07 28.9 6.0 0.99 10.2 0.0 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat CHAD PF05235.14 ORX95173.1 - 1.6e-05 25.0 0.5 0.33 10.9 0.1 3.9 2 1 2 4 4 4 3 CHAD domain AAA_16 PF13191.6 ORX95173.1 - 0.0002 21.8 0.0 0.00074 19.9 0.0 2.0 2 1 0 2 2 1 1 AAA ATPase domain AAA_22 PF13401.6 ORX95173.1 - 0.00084 19.6 0.0 0.0022 18.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain PPR PF01535.20 ORX95173.1 - 0.0017 18.5 1.8 18 5.9 0.0 5.5 6 0 0 6 6 5 0 PPR repeat TPR_6 PF13174.6 ORX95173.1 - 0.0022 18.5 20.6 8.9 7.2 0.3 6.2 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 ORX95173.1 - 0.0041 17.6 9.2 1.2 9.7 1.2 4.2 1 1 3 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 ORX95173.1 - 0.0073 16.5 4.0 3.3 8.0 0.1 3.7 1 1 2 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 ORX95173.1 - 0.023 14.8 13.8 4.6 7.5 0.3 4.8 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_5 PF12688.7 ORX95173.1 - 0.26 11.5 2.4 1 9.6 0.1 2.9 2 1 1 3 3 3 0 Tetratrico peptide repeat DUF4810 PF16068.5 ORX95173.1 - 0.29 11.7 6.4 15 6.2 0.1 4.3 4 0 0 4 4 4 0 Domain of unknown function (DUF4810) MIT PF04212.18 ORX95173.1 - 0.4 10.8 4.1 1.4e+02 2.7 0.1 4.4 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_3 PF07720.12 ORX95173.1 - 0.75 9.9 8.3 0.12 12.4 1.5 3.3 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 ORX95173.1 - 7.7 6.3 17.7 8.5 6.2 0.3 5.6 4 2 0 5 5 5 0 TPR repeat zf-NADH-PPase PF09297.11 ORX95174.1 - 0.064 12.9 0.4 2.5 7.8 0.0 2.5 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Uma2 PF05685.12 ORX95175.1 - 0.07 12.7 0.1 0.21 11.1 0.1 1.9 1 1 0 1 1 1 0 Putative restriction endonuclease WD40 PF00400.32 ORX95176.1 - 6.5e-83 270.5 45.9 4.9e-11 43.0 0.3 9.6 8 1 1 9 9 9 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX95176.1 - 4.4e-29 100.6 1.2 0.00072 19.8 0.0 7.5 1 1 6 7 7 7 7 Anaphase-promoting complex subunit 4 WD40 domain NACHT PF05729.12 ORX95176.1 - 2.5e-18 66.5 0.2 5.2e-18 65.5 0.2 1.5 1 0 0 1 1 1 1 NACHT domain Ge1_WD40 PF16529.5 ORX95176.1 - 1.5e-15 57.0 12.0 0.013 14.5 0.2 8.7 1 1 7 8 8 8 5 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 ORX95176.1 - 4.8e-08 32.1 12.1 0.59 8.7 0.3 6.2 1 1 6 7 7 7 5 Nucleoporin Nup120/160 WD40_like PF17005.5 ORX95176.1 - 0.0049 16.3 1.7 51 3.1 0.0 4.7 2 1 3 6 6 6 0 WD40-like domain KAP_NTPase PF07693.14 ORX95176.1 - 0.025 13.8 0.2 0.057 12.6 0.2 1.5 1 1 0 1 1 1 0 KAP family P-loop domain Slx4 PF09494.10 ORX95176.1 - 0.068 13.1 0.2 0.25 11.3 0.1 2.1 2 0 0 2 2 2 0 Slx4 endonuclease DUF5643 PF18705.1 ORX95176.1 - 0.092 12.7 0.0 23 5.0 0.0 3.4 2 1 0 3 3 3 0 Family of unknown function (DUF5643) TPR_12 PF13424.6 ORX95177.1 - 2e-59 197.8 47.6 9.3e-15 54.7 3.8 5.7 2 1 4 6 6 6 6 Tetratricopeptide repeat TPR_10 PF13374.6 ORX95177.1 - 2e-47 157.8 19.4 2e-10 40.2 0.1 7.6 7 1 1 8 8 8 7 Tetratricopeptide repeat TPR_1 PF00515.28 ORX95177.1 - 8e-24 82.4 37.6 2.7e-05 23.8 0.8 7.2 7 0 0 7 7 6 6 Tetratricopeptide repeat TPR_MalT PF17874.1 ORX95177.1 - 2.9e-22 79.5 10.3 2.1e-09 37.2 1.8 3.3 1 1 2 3 3 3 3 MalT-like TPR region TPR_2 PF07719.17 ORX95177.1 - 1.2e-16 59.4 33.8 0.0022 18.0 0.4 7.6 8 0 0 8 8 7 5 Tetratricopeptide repeat TPR_14 PF13428.6 ORX95177.1 - 4.2e-16 58.3 21.1 0.02 15.7 1.0 7.4 5 2 3 8 8 8 5 Tetratricopeptide repeat TPR_7 PF13176.6 ORX95177.1 - 5.2e-14 51.2 15.2 0.0022 17.9 0.1 7.1 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.6 ORX95177.1 - 7.6e-13 47.6 30.1 0.0031 17.6 0.2 7.5 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_4 PF07721.14 ORX95177.1 - 7.5e-09 35.4 0.0 5.2 8.0 0.0 6.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_21 PF09976.9 ORX95177.1 - 3.8e-08 33.3 23.0 0.26 11.0 0.3 6.4 3 2 3 6 6 6 5 Tetratricopeptide repeat-like domain DUF2225 PF09986.9 ORX95177.1 - 7.6e-08 32.3 9.3 0.0058 16.4 0.6 3.8 1 1 3 4 4 4 3 Uncharacterized protein conserved in bacteria (DUF2225) TPR_16 PF13432.6 ORX95177.1 - 5.3e-07 30.2 28.0 0.11 13.2 0.7 6.3 7 1 0 7 7 6 4 Tetratricopeptide repeat TPR_19 PF14559.6 ORX95177.1 - 8.1e-06 26.3 26.5 0.016 15.7 1.8 5.9 4 2 2 6 6 5 4 Tetratricopeptide repeat RPN7 PF10602.9 ORX95177.1 - 1.2e-05 25.1 10.7 2 8.1 0.1 5.8 3 2 3 6 6 6 2 26S proteasome subunit RPN7 DUF4810 PF16068.5 ORX95177.1 - 2.4e-05 24.8 11.4 2.5 8.7 0.0 5.5 6 0 0 6 6 6 2 Domain of unknown function (DUF4810) TPR_11 PF13414.6 ORX95177.1 - 9.4e-05 22.0 29.3 0.071 12.8 1.0 6.1 5 0 0 5 5 5 3 TPR repeat TPR_17 PF13431.6 ORX95177.1 - 0.00036 20.7 17.6 0.87 10.1 0.2 6.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_3 PF07720.12 ORX95177.1 - 0.00048 20.0 16.7 0.65 10.1 0.0 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat SRP68 PF16969.5 ORX95177.1 - 0.00072 18.7 10.6 0.91 8.4 0.4 4.4 1 1 2 4 4 4 2 RNA-binding signal recognition particle 68 DUF4388 PF14332.6 ORX95177.1 - 0.001 19.3 2.1 15 5.9 0.0 4.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4388) DUF630 PF04783.12 ORX95177.1 - 0.001 19.2 11.5 13 6.1 0.0 5.7 7 0 0 7 7 6 0 Protein of unknown function (DUF630) PPR PF01535.20 ORX95177.1 - 0.01 16.0 7.5 97 3.6 0.0 6.6 7 0 0 7 7 7 0 PPR repeat TPR_6 PF13174.6 ORX95177.1 - 0.021 15.4 29.7 1.1 10.0 0.2 6.6 7 0 0 7 7 7 0 Tetratricopeptide repeat DUF5113 PF17140.4 ORX95177.1 - 0.6 9.9 9.5 30 4.4 0.1 5.0 4 1 1 6 6 6 0 Domain of unknown function (DUF5113) CysG_dimeriser PF10414.9 ORX95177.1 - 0.98 9.2 5.7 1.8e+02 1.9 0.1 5.1 6 0 0 6 6 6 0 Sirohaem synthase dimerisation region BTAD PF03704.17 ORX95177.1 - 2.2 8.7 11.1 22 5.5 0.1 4.7 4 1 1 5 5 5 0 Bacterial transcriptional activator domain MIT PF04212.18 ORX95177.1 - 7.2 6.8 20.5 4.4 7.4 0.6 5.2 6 0 0 6 6 6 0 MIT (microtubule interacting and transport) domain Ribonuc_2-5A PF06479.12 ORX95179.1 - 0.048 13.8 0.0 0.05 13.8 0.0 1.0 1 0 0 1 1 1 0 Ribonuclease 2-5A OPT PF03169.15 ORX95200.1 - 2.8e-91 307.0 18.6 3.2e-91 306.9 18.6 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein CBM_14 PF01607.24 ORX95200.1 - 0.14 12.3 0.2 0.26 11.5 0.2 1.4 1 0 0 1 1 1 0 Chitin binding Peritrophin-A domain Egh16-like PF11327.8 ORX95201.1 - 2.1e-50 171.7 7.4 2.1e-50 171.7 7.4 2.4 2 1 0 2 2 2 1 Egh16-like virulence factor Izumo-Ig PF16706.5 ORX95201.1 - 0.017 15.1 0.0 0.032 14.3 0.0 1.3 1 0 0 1 1 1 0 Izumo-like Immunoglobulin domain I-set PF07679.16 ORX95201.1 - 0.097 12.8 0.1 0.21 11.7 0.1 1.6 1 0 0 1 1 1 0 Immunoglobulin I-set domain Polysacc_deac_1 PF01522.21 ORX95202.1 - 0.086 12.7 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 Polysaccharide deacetylase Anp1 PF03452.14 ORX95203.1 - 2.7 7.3 6.0 4.9 6.5 6.0 1.4 1 0 0 1 1 1 0 Anp1 FMN_bind_2 PF04299.12 ORX95204.1 - 0.018 14.8 0.1 0.035 13.8 0.1 1.4 1 0 0 1 1 1 0 Putative FMN-binding domain ORF6N PF10543.9 ORX95204.1 - 0.06 13.6 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 ORF6N domain DUF3425 PF11905.8 ORX95205.1 - 6.5e-18 64.9 0.5 1.9e-17 63.4 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 ORX95205.1 - 0.11 12.6 5.2 0.18 11.9 5.2 1.3 1 0 0 1 1 1 0 bZIP transcription factor DIOX_N PF14226.6 ORX95206.1 - 0.0038 18.0 0.0 0.0072 17.1 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 ORX95206.1 - 0.014 15.9 0.0 0.029 14.9 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily GCV_T PF01571.21 ORX95207.1 - 7e-09 35.4 0.0 1e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain RTA1 PF04479.13 ORX95210.1 - 9.1e-51 172.4 8.0 1.4e-50 171.8 8.0 1.3 1 0 0 1 1 1 1 RTA1 like protein Lyx_isomer PF07385.12 ORX95210.1 - 0.11 11.7 0.0 0.22 10.7 0.0 1.4 1 0 0 1 1 1 0 D-lyxose isomerase DUF4211 PF13926.6 ORX95211.1 - 1.3e-43 148.5 0.2 4.7e-43 146.7 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4211) BppU_IgG PF18667.1 ORX95211.1 - 0.17 12.0 0.0 0.38 10.9 0.0 1.5 1 0 0 1 1 1 0 Baseplate upper protein immunoglobulin like domain CRAL_TRIO PF00650.20 ORX95212.1 - 9.7e-39 132.6 0.0 1.3e-38 132.3 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 ORX95212.1 - 2.5e-15 56.4 0.8 5.6e-15 55.3 0.8 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 ORX95212.1 - 1.3e-07 31.9 0.0 2.1e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain vWA-TerF-like PF10138.9 ORX95213.1 - 0.00049 20.3 0.0 0.00074 19.7 0.0 1.4 1 0 0 1 1 1 1 vWA found in TerF C terminus Cu_bind_like PF02298.17 ORX95214.1 - 0.011 15.7 0.0 0.019 14.9 0.0 1.4 1 1 0 1 1 1 0 Plastocyanin-like domain Copper-bind PF00127.20 ORX95214.1 - 0.098 13.1 0.2 0.22 12.0 0.2 1.6 1 1 0 1 1 1 0 Copper binding proteins, plastocyanin/azurin family VIR_N PF15912.5 ORX95214.1 - 0.25 10.9 2.9 0.32 10.6 2.9 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal CAP_N PF01213.19 ORX95214.1 - 1 8.7 4.4 1.4 8.3 4.4 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Cys_rich_CPCC PF14206.6 ORX95215.1 - 0.03 14.1 1.3 1.2 9.0 0.0 2.4 1 1 1 2 2 2 0 Cysteine-rich CPCC Pyocin_S PF06958.12 ORX95215.1 - 0.083 13.4 0.1 0.14 12.7 0.1 1.5 1 0 0 1 1 1 0 S-type Pyocin TPPK_C PF12555.8 ORX95215.1 - 0.33 11.0 1.9 0.68 10.0 1.9 1.5 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal DUF745 PF05335.13 ORX95216.1 - 0.32 10.7 10.2 1.5 8.5 4.8 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF745) PI-PLC-X PF00388.19 ORX95217.1 - 2.3e-49 166.7 0.0 3.9e-49 166.0 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 ORX95217.1 - 1e-38 132.2 0.0 1.7e-38 131.5 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 ORX95217.1 - 0.011 16.0 0.0 0.031 14.6 0.0 1.7 1 0 0 1 1 1 0 C2 domain DUF2250 PF10007.9 ORX95219.1 - 0.14 12.2 0.8 0.27 11.4 0.8 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) DUF2069 PF09842.9 ORX95219.1 - 0.25 11.6 6.2 0.087 13.0 1.3 2.6 2 1 0 2 2 2 0 Predicted membrane protein (DUF2069) ChaB PF06150.12 ORX95219.1 - 0.32 11.6 1.5 0.43 11.2 0.4 1.8 2 0 0 2 2 2 0 ChaB DUF2207 PF09972.9 ORX95219.1 - 0.47 9.2 5.1 0.36 9.5 2.7 2.1 1 1 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF4064 PF13273.6 ORX95219.1 - 1.6 9.1 11.2 18 5.7 5.9 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) FMN_dh PF01070.18 ORX95253.1 - 3.4e-88 296.0 0.0 9.2e-85 284.7 0.0 2.0 1 1 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 ORX95253.1 - 2.6e-05 23.4 0.5 0.0019 17.3 0.1 2.2 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.21 ORX95253.1 - 0.0009 18.8 0.0 1.3 8.4 0.0 3.0 3 0 0 3 3 3 2 Histidine biosynthesis protein DHO_dh PF01180.21 ORX95253.1 - 0.0043 16.3 0.0 0.4 9.8 0.0 2.3 2 0 0 2 2 2 1 Dihydroorotate dehydrogenase Glu_synthase PF01645.17 ORX95253.1 - 0.01 15.0 0.0 0.015 14.5 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.15 ORX95253.1 - 0.019 14.4 0.0 0.03 13.7 0.0 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase G3P_antiterm PF04309.12 ORX95253.1 - 0.055 12.9 0.0 1.2 8.6 0.0 2.6 3 0 0 3 3 3 0 Glycerol-3-phosphate responsive antiterminator Peptidase_M19 PF01244.21 ORX95253.1 - 0.063 12.4 0.0 0.24 10.5 0.0 2.0 2 0 0 2 2 2 0 Membrane dipeptidase (Peptidase family M19) GMC_oxred_N PF00732.19 ORX95254.1 - 6.7e-47 160.3 0.0 8.9e-47 159.9 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 ORX95254.1 - 2.4e-35 122.2 0.0 4e-35 121.5 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GIDA PF01134.22 ORX95254.1 - 0.0045 16.1 0.0 0.1 11.6 0.0 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 ORX95254.1 - 0.0099 15.2 0.0 2.7 7.2 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORX95254.1 - 0.015 15.5 0.1 0.034 14.4 0.1 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 ORX95254.1 - 0.02 13.9 0.6 0.052 12.6 0.0 1.9 3 0 0 3 3 3 0 Lycopene cyclase protein Pyr_redox_2 PF07992.14 ORX95254.1 - 0.062 12.5 0.0 0.61 9.3 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Ric8 PF10165.9 ORX95255.1 - 1.2 8.1 4.7 0.74 8.8 3.6 1.2 1 1 0 1 1 1 0 Guanine nucleotide exchange factor synembryn Oxidored_molyb PF00174.19 ORX95256.1 - 1.4e-42 145.2 0.0 3e-42 144.1 0.0 1.5 2 0 0 2 2 2 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 ORX95256.1 - 1.7e-10 41.1 0.3 4.2e-10 39.8 0.3 1.6 1 1 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Big_7 PF17957.1 ORX95256.1 - 0.018 15.8 0.0 0.047 14.5 0.0 1.7 1 0 0 1 1 1 0 Bacterial Ig domain CN_hydrolase PF00795.22 ORX95257.1 - 3.9e-34 118.2 0.0 9.4e-34 116.9 0.0 1.6 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase PAN_4 PF14295.6 ORX95258.1 - 0.0076 16.1 3.8 0.026 14.4 3.8 1.9 1 0 0 1 1 1 1 PAN domain PAN_3 PF08277.12 ORX95258.1 - 0.54 10.1 8.1 0.083 12.7 3.0 2.3 2 0 0 2 2 2 0 PAN-like domain p450 PF00067.22 ORX95259.1 - 3.1e-65 220.7 0.0 4e-65 220.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Ank_4 PF13637.6 ORX95260.1 - 4.2e-20 71.8 0.0 8.3e-09 35.8 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORX95260.1 - 7.3e-17 59.7 0.6 0.00043 20.5 0.0 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_2 PF12796.7 ORX95260.1 - 2.6e-16 60.0 0.0 3.5e-11 43.6 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 ORX95260.1 - 9.7e-15 54.3 0.6 0.0022 18.3 0.0 4.0 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 ORX95260.1 - 2.6e-11 43.5 0.5 9.6e-06 25.8 0.1 3.1 2 2 1 3 3 3 2 Ankyrin repeats (many copies) Det1 PF09737.9 ORX95282.1 - 0.018 14.2 0.3 0.018 14.2 0.3 1.0 1 0 0 1 1 1 0 De-etiolated protein 1 Det1 DUF3530 PF12048.8 ORX95282.1 - 0.093 12.1 0.0 0.095 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) DUF3723 PF12520.8 ORX95283.1 - 1.8e-14 53.3 0.5 2e-14 53.2 0.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3723) Pox_MCEL PF03291.16 ORX95283.1 - 0.02 14.0 0.2 0.021 13.9 0.2 1.1 1 0 0 1 1 1 0 mRNA capping enzyme MULE PF10551.9 ORX95285.1 - 0.0037 17.7 0.0 0.0042 17.5 0.0 1.0 1 0 0 1 1 1 1 MULE transposase domain zf-C2H2 PF00096.26 ORX95303.1 - 1e-05 25.7 26.7 0.03 14.8 0.3 4.4 4 0 0 4 4 4 4 Zinc finger, C2H2 type FOXP-CC PF16159.5 ORX95303.1 - 1.1 10.0 13.5 1.4 9.6 1.8 3.2 2 1 1 3 3 3 0 FOXP coiled-coil domain DUF629 PF04780.12 ORX95303.1 - 1.6 7.2 8.3 0.054 12.0 2.4 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF629) zf-C2H2_4 PF13894.6 ORX95303.1 - 3 8.9 26.7 0.56 11.2 1.4 4.4 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2 PF00096.26 ORX95304.1 - 0.0016 18.8 45.5 1.2 9.7 1.6 7.1 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORX95304.1 - 0.023 15.5 10.6 0.032 15.1 4.9 8.0 9 0 0 9 9 9 0 C2H2-type zinc finger DUF1677 PF07911.13 ORX95304.1 - 2.5 8.6 7.4 1.1 9.7 0.4 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1677) F-box-like PF12937.7 ORX95305.1 - 6.1e-07 29.2 0.0 1.2e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORX95305.1 - 0.012 15.5 0.1 0.03 14.2 0.1 1.7 1 0 0 1 1 1 0 F-box domain ADH_N PF08240.12 ORX95307.1 - 1.1e-25 89.6 5.9 1.7e-25 89.0 5.9 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORX95307.1 - 1.7e-19 70.1 0.0 3.3e-19 69.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ORX95307.1 - 6e-10 40.3 0.0 9.8e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 ORX95307.1 - 0.0025 17.2 0.2 0.0044 16.4 0.2 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 ORX95307.1 - 0.0061 15.9 0.0 0.0092 15.3 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.20 ORX95307.1 - 0.079 13.0 0.0 0.37 10.9 0.0 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 ORX95308.1 - 7.5e-18 64.9 0.5 1.7e-09 37.4 0.1 2.4 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 ORX95308.1 - 1.5e-05 25.1 0.2 4.4e-05 23.6 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ORX95308.1 - 0.00052 19.3 0.0 0.0039 16.5 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORX95308.1 - 0.00074 20.0 0.0 0.0032 18.0 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 ORX95308.1 - 0.0018 17.6 0.0 0.57 9.4 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Thi4 PF01946.17 ORX95308.1 - 0.0079 15.5 0.0 0.013 14.7 0.0 1.3 1 0 0 1 1 1 1 Thi4 family IlvN PF07991.12 ORX95308.1 - 0.008 15.8 0.0 0.021 14.4 0.0 1.7 1 1 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain FAD_binding_2 PF00890.24 ORX95308.1 - 0.011 14.8 0.0 0.022 13.9 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.24 ORX95308.1 - 0.013 15.1 0.3 0.018 14.6 0.3 1.7 1 1 0 1 1 1 0 FAD dependent oxidoreductase PALP PF00291.25 ORX95308.1 - 0.029 13.8 0.0 0.043 13.2 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme ApbA PF02558.16 ORX95308.1 - 0.064 12.9 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.18 ORX95308.1 - 0.07 13.4 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain NAD_Gly3P_dh_N PF01210.23 ORX95308.1 - 0.1 12.5 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Shikimate_DH PF01488.20 ORX95308.1 - 0.14 12.2 0.0 0.24 11.5 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pyr_redox_3 PF13738.6 ORX95308.1 - 0.2 10.9 0.0 0.69 9.1 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_23 PF13489.6 ORX95309.1 - 1.1e-19 70.9 0.7 1.5e-19 70.5 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORX95309.1 - 2.4e-12 47.4 0.0 6.9e-12 45.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORX95309.1 - 3.2e-09 37.3 0.0 7.6e-09 36.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORX95309.1 - 9.1e-09 36.0 0.0 6.8e-08 33.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORX95309.1 - 2.5e-06 27.4 0.0 0.0055 16.5 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Ubie_methyltran PF01209.18 ORX95309.1 - 0.00054 19.4 0.0 0.0039 16.5 0.0 2.0 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 ORX95309.1 - 0.0016 17.8 0.0 0.0044 16.4 0.0 1.5 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_16 PF10294.9 ORX95309.1 - 0.0018 18.0 0.0 0.0029 17.4 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_4 PF02390.17 ORX95309.1 - 0.0058 16.1 0.0 0.0095 15.4 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.14 ORX95309.1 - 0.0061 16.1 0.0 0.018 14.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain PrmA PF06325.13 ORX95309.1 - 0.012 15.1 0.0 0.019 14.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_2 PF00891.18 ORX95309.1 - 0.016 14.5 0.0 0.035 13.4 0.0 1.5 1 0 0 1 1 1 0 O-methyltransferase domain Ank_4 PF13637.6 ORX95310.1 - 5.7e-08 33.1 0.3 0.001 19.6 0.0 3.9 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 ORX95310.1 - 4.8e-06 27.1 0.0 0.00072 20.1 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ORX95310.1 - 2.7e-05 24.3 0.1 0.00037 20.7 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 ORX95310.1 - 0.0094 16.4 0.7 1.2 9.7 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 ORX95310.1 - 0.011 16.2 0.2 17 6.4 0.0 4.3 4 0 0 4 4 4 0 Ankyrin repeat Bim_N PF06773.11 ORX95310.1 - 0.024 14.3 1.9 3.2 7.5 0.7 2.7 2 0 0 2 2 2 0 Bim protein N-terminus E1-E2_ATPase PF00122.20 ORX95311.1 - 1.8e-46 157.9 1.4 3.3e-45 153.8 0.1 3.2 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 ORX95311.1 - 1.1e-35 123.9 0.3 6.1e-35 121.4 0.3 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 ORX95311.1 - 5.8e-26 90.7 0.0 1.9e-10 41.0 0.0 3.5 3 0 0 3 3 3 3 Heavy-metal-associated domain Hydrolase_3 PF08282.12 ORX95311.1 - 0.0049 16.6 1.0 0.01 15.6 0.1 2.0 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 ORX95311.1 - 0.01 16.2 0.0 0.12 12.7 0.0 2.7 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase HMA PF00403.26 ORX95312.1 - 0.00023 21.6 0.0 0.0005 20.5 0.0 1.6 1 1 0 1 1 1 1 Heavy-metal-associated domain TusA PF01206.17 ORX95312.1 - 0.14 12.0 0.0 0.25 11.2 0.0 1.4 1 1 0 1 1 1 0 Sulfurtransferase TusA Tropomyosin_1 PF12718.7 ORX95313.1 - 0.0089 16.2 2.3 0.013 15.7 2.3 1.2 1 0 0 1 1 1 1 Tropomyosin like AJAP1_PANP_C PF15298.6 ORX95313.1 - 0.21 11.8 5.7 0.41 10.8 5.7 1.5 1 0 0 1 1 1 0 AJAP1/PANP C-terminus ORC6 PF05460.13 ORX95313.1 - 1.2 8.3 6.8 1.6 7.9 6.8 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) ATG16 PF08614.11 ORX95313.1 - 1.3 9.2 6.0 0.12 12.6 0.6 1.8 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Glyco_transf_34 PF05637.12 ORX95314.1 - 3.9e-29 102.0 8.6 3.1e-27 95.8 8.6 2.0 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Peptidase_M28 PF04389.17 ORX95315.1 - 5.6e-22 78.4 0.9 6.3e-21 75.0 0.2 2.5 2 1 0 2 2 2 1 Peptidase family M28 Peptidase_M20 PF01546.28 ORX95315.1 - 0.0001 22.1 0.0 0.00017 21.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 ATP_synth_reg PF14960.6 ORX95315.1 - 0.035 13.6 0.8 1.1 8.8 0.0 2.5 2 0 0 2 2 2 0 ATP synthase regulation MaoC_dehydratas PF01575.19 ORX95315.1 - 0.04 13.5 0.8 0.53 9.9 0.3 2.3 2 0 0 2 2 2 0 MaoC like domain GMC_oxred_N PF00732.19 ORX95316.1 - 1.6e-54 185.3 0.0 2.2e-54 184.9 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 ORX95316.1 - 1e-31 110.4 0.0 1.7e-31 109.7 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 ORX95316.1 - 3.7e-06 26.3 0.0 0.02 14.0 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 ORX95316.1 - 0.0079 16.4 0.0 0.0079 16.4 0.0 2.4 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ORX95316.1 - 0.011 15.0 0.0 0.044 13.0 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ORX95316.1 - 0.019 13.7 0.1 0.87 8.2 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Lycopene_cycl PF05834.12 ORX95316.1 - 0.026 13.6 0.0 0.047 12.7 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.17 ORX95316.1 - 0.042 13.1 0.0 0.3 10.3 0.1 2.1 2 0 0 2 2 2 0 Thi4 family Pyr_redox_3 PF13738.6 ORX95316.1 - 0.076 12.3 0.0 0.79 8.9 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ORX95316.1 - 0.13 11.8 0.5 0.32 10.5 0.5 1.8 1 1 0 1 1 1 0 FAD dependent oxidoreductase Beta-lactamase PF00144.24 ORX95317.1 - 1.3e-38 133.1 0.0 2.2e-38 132.3 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase CorA PF01544.18 ORX95318.1 - 1.4e-09 37.7 0.1 2.1e-09 37.1 0.1 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF3533 PF12051.8 ORX95318.1 - 0.27 10.1 0.9 0.39 9.6 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) CSTF2_hinge PF14327.6 ORX95351.1 - 2e-30 105.1 0.5 2e-30 105.1 0.5 2.1 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.22 ORX95351.1 - 2.8e-19 68.7 0.0 4.1e-19 68.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.6 ORX95351.1 - 3.7e-09 36.0 7.9 3.7e-09 36.0 7.9 1.8 2 0 0 2 2 2 1 Transcription termination and cleavage factor C-terminal Cu_amine_oxid PF01179.20 ORX95352.1 - 1.5e-159 531.3 0.0 1.8e-159 531.1 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.16 ORX95352.1 - 1.4e-11 44.4 0.0 3e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.16 ORX95352.1 - 0.0028 18.0 0.0 0.0079 16.6 0.0 1.7 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Glyco_hydro_61 PF03443.14 ORX95353.1 - 2.2e-48 164.9 0.3 2.6e-48 164.7 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 ChiW_Ig_like PF18683.1 ORX95353.1 - 0.069 13.4 0.3 0.12 12.6 0.3 1.4 1 0 0 1 1 1 0 Chitinase W immunoglobulin-like domain ABC_tran PF00005.27 ORX95355.1 - 4e-46 156.9 0.4 2.1e-22 80.1 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC2_membrane PF01061.24 ORX95355.1 - 8.4e-46 156.0 32.2 5.9e-25 87.9 13.6 2.3 2 0 0 2 2 2 2 ABC-2 type transporter RsgA_GTPase PF03193.16 ORX95355.1 - 3.4e-10 40.1 1.4 8.4e-05 22.5 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 ORX95355.1 - 2.4e-09 37.8 0.2 0.0019 18.6 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 ORX95355.1 - 2.4e-08 34.1 11.4 0.015 15.2 0.0 4.3 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 ORX95355.1 - 3.7e-07 30.8 0.2 0.003 18.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.19 ORX95355.1 - 6.5e-07 29.0 1.8 0.012 15.1 0.0 3.8 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 ORX95355.1 - 1.1e-05 25.7 0.2 0.02 15.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 ORX95355.1 - 1.3e-05 24.9 2.7 0.099 12.4 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain NACHT PF05729.12 ORX95355.1 - 4.2e-05 23.5 0.0 0.37 10.7 0.0 2.9 2 0 0 2 2 2 2 NACHT domain AAA_28 PF13521.6 ORX95355.1 - 4.6e-05 23.7 0.9 0.51 10.6 0.3 3.3 4 0 0 4 4 3 2 AAA domain T2SSE PF00437.20 ORX95355.1 - 0.00023 20.3 0.3 0.25 10.4 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein ATPase_2 PF01637.18 ORX95355.1 - 0.00025 21.1 0.1 0.015 15.3 0.0 2.5 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_25 PF13481.6 ORX95355.1 - 0.00027 20.6 0.1 0.54 9.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 ORX95355.1 - 0.00039 20.2 0.0 0.32 10.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 ORX95355.1 - 0.00045 20.6 0.0 1.3 9.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain cobW PF02492.19 ORX95355.1 - 0.00056 19.5 2.0 0.56 9.8 0.1 2.5 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain Roc PF08477.13 ORX95355.1 - 0.00078 19.7 0.3 0.87 9.8 0.1 2.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 ORX95355.1 - 0.00085 19.4 3.1 0.97 9.5 0.1 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_24 PF13479.6 ORX95355.1 - 0.0014 18.4 0.8 1.6 8.5 0.0 2.7 3 0 0 3 3 3 2 AAA domain AAA PF00004.29 ORX95355.1 - 0.0027 18.1 0.1 3.7 8.0 0.0 2.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 ORX95355.1 - 0.004 17.5 0.4 0.52 10.7 0.1 2.8 3 0 0 3 3 2 1 RNA helicase SbcCD_C PF13558.6 ORX95355.1 - 0.0063 16.7 0.2 4.1 7.7 0.1 3.5 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit G-alpha PF00503.20 ORX95355.1 - 0.0071 15.5 0.4 0.63 9.1 0.2 2.6 2 1 0 2 2 2 1 G-protein alpha subunit AAA_5 PF07728.14 ORX95355.1 - 0.0082 16.1 0.9 3.3 7.7 0.0 3.2 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 ORX95355.1 - 0.013 15.7 1.5 4.3 7.5 0.0 2.9 2 1 0 2 2 2 0 AAA domain AAA_15 PF13175.6 ORX95355.1 - 0.016 15.0 1.9 11 5.6 0.0 3.2 3 0 0 3 3 3 0 AAA ATPase domain MobB PF03205.14 ORX95355.1 - 0.017 15.0 1.3 4.3 7.3 0.1 2.9 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B KAP_NTPase PF07693.14 ORX95355.1 - 0.022 14.0 0.0 2.9 7.0 0.0 2.2 2 0 0 2 2 2 0 KAP family P-loop domain DUF2075 PF09848.9 ORX95355.1 - 0.03 13.6 0.2 1.5 8.0 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) ATP_bind_1 PF03029.17 ORX95355.1 - 0.038 13.8 1.0 7.4 6.3 0.2 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_7 PF12775.7 ORX95355.1 - 0.041 13.4 0.4 3.5 7.1 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region PduV-EutP PF10662.9 ORX95355.1 - 0.052 13.3 1.8 4.8 6.9 0.0 2.8 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.23 ORX95355.1 - 0.053 13.6 1.8 8.7 6.4 0.2 2.6 2 0 0 2 2 2 0 Dynamin family FtsK_SpoIIIE PF01580.18 ORX95355.1 - 0.079 12.3 1.0 11 5.3 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family SRPRB PF09439.10 ORX95355.1 - 0.093 12.2 0.9 9.7 5.6 0.1 2.6 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit DUF4388 PF14332.6 ORX95355.1 - 0.13 12.5 0.0 37 4.7 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4388) NTPase_1 PF03266.15 ORX95355.1 - 0.14 12.0 0.2 45 3.9 0.0 3.3 4 0 0 4 4 4 0 NTPase AAA_18 PF13238.6 ORX95355.1 - 0.2 12.2 0.1 18 5.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_35 PF14516.6 ORX95355.1 - 0.21 10.4 0.2 2.7 6.7 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain Pox_A32 PF04665.12 ORX95355.1 - 0.25 10.8 3.2 6.8 6.1 0.6 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein Zeta_toxin PF06414.12 ORX95355.1 - 0.29 10.4 1.1 6.3 6.0 0.2 2.4 2 0 0 2 2 2 0 Zeta toxin PRK PF00485.18 ORX95355.1 - 0.32 10.7 1.2 12 5.6 0.2 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Fungal_trans_2 PF11951.8 ORX95356.1 - 5.2e-57 193.4 0.1 8.4e-57 192.7 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORX95356.1 - 8.1e-09 35.5 11.6 1.6e-08 34.5 11.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Lactamase_B_6 PF16661.5 ORX95357.1 - 1.2e-66 223.8 0.0 1.8e-66 223.2 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain CPSF100_C PF13299.6 ORX95357.1 - 9.4e-50 169.1 0.0 3.2e-49 167.4 0.0 2.0 2 0 0 2 2 2 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.8 ORX95357.1 - 6.8e-19 68.2 0.0 2.1e-18 66.6 0.0 1.9 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.12 ORX95357.1 - 3.4e-12 46.1 0.0 7.2e-12 45.1 0.0 1.6 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain TamB PF04357.13 ORX95357.1 - 0.0007 18.9 0.1 0.0007 18.9 0.1 1.5 2 0 0 2 2 2 1 TamB, inner membrane protein subunit of TAM complex Lactamase_B PF00753.27 ORX95357.1 - 0.0033 17.5 0.0 0.0074 16.3 0.0 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily zf-CCCH PF00642.24 ORX95358.1 - 2e-09 37.1 10.9 3.6e-05 23.5 2.3 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 ORX95358.1 - 1.6e-08 34.1 10.2 1.1e-05 25.0 2.5 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 ORX95358.1 - 1.5e-07 31.2 18.8 0.00049 20.1 3.6 2.4 2 0 0 2 2 2 2 Zinc finger domain Torus PF16131.5 ORX95358.1 - 1.7e-07 31.9 6.9 0.00053 20.7 0.4 2.4 1 1 1 2 2 2 2 Torus domain zf-CCCH_3 PF15663.5 ORX95358.1 - 7.1e-05 23.0 1.0 0.00015 21.9 1.0 1.5 1 0 0 1 1 1 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 ORX95358.1 - 0.084 13.4 13.5 0.96 10.0 2.4 2.6 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger ANAPC4_WD40 PF12894.7 ORX95361.1 - 2e-08 34.4 0.2 0.065 13.5 0.0 4.8 5 1 1 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 ORX95361.1 - 0.00065 20.5 3.4 11 7.1 0.0 5.3 6 0 0 6 6 6 1 WD domain, G-beta repeat PD40 PF07676.12 ORX95361.1 - 0.0021 17.9 0.0 1.6 8.8 0.0 2.7 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat Myb_DNA-bind_6 PF13921.6 ORX95371.1 - 7.7e-05 22.9 0.0 0.00017 21.7 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 ORX95371.1 - 0.00014 22.0 0.0 0.00033 20.8 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Pkinase PF00069.25 ORX95372.1 - 3.2e-20 72.6 0.0 9.5e-19 67.8 0.0 2.6 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX95372.1 - 4.9e-11 42.4 0.0 3e-09 36.6 0.0 2.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 ORX95372.1 - 0.0062 15.9 0.2 0.014 14.8 0.1 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1188 PF06690.11 ORX95372.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1188) AAA PF00004.29 ORX95375.1 - 1.7e-18 67.3 0.0 7.5e-18 65.2 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 ORX95375.1 - 1.2e-06 29.0 0.2 1.1e-05 25.9 0.1 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 ORX95375.1 - 0.00026 21.3 0.2 0.0062 16.8 0.3 3.0 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 ORX95375.1 - 0.0011 19.0 0.0 0.01 15.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.6 ORX95375.1 - 0.028 14.9 0.0 0.089 13.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 ORX95375.1 - 0.066 13.4 0.2 0.38 10.9 0.2 2.3 1 1 0 1 1 1 0 AAA domain RuvB_N PF05496.12 ORX95375.1 - 0.077 12.7 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 ORX95375.1 - 0.077 13.5 0.0 0.31 11.6 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 ORX95375.1 - 0.095 12.4 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.14 ORX95375.1 - 0.15 12.2 0.0 0.38 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_11 PF13086.6 ORX95375.1 - 0.16 11.7 0.0 0.32 10.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Hydin_ADK PF17213.3 ORX95375.1 - 0.18 12.1 0.1 0.35 11.1 0.1 1.4 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Pkinase_fungal PF17667.1 ORX95376.1 - 1.7e-48 165.4 4.3 1.3e-43 149.3 1.0 4.3 1 1 1 2 2 2 2 Fungal protein kinase EamA PF00892.20 ORX95378.1 - 0.018 15.2 1.2 0.023 14.8 0.3 1.6 1 1 1 2 2 2 0 EamA-like transporter family Ad_cyc_g-alpha PF08509.11 ORX95378.1 - 0.1 12.3 0.3 0.16 11.7 0.3 1.3 1 0 0 1 1 1 0 Adenylate cyclase G-alpha binding domain DUF3435 PF11917.8 ORX95381.1 - 8.5e-146 486.1 0.7 1.2e-145 485.7 0.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) UvsY PF11056.8 ORX95381.1 - 0.047 14.0 0.1 0.096 13.0 0.1 1.5 1 0 0 1 1 1 0 Recombination, repair and ssDNA binding protein UvsY CCDC32 PF14989.6 ORX95381.1 - 0.17 11.9 3.1 0.47 10.5 0.8 2.4 2 0 0 2 2 2 0 Coiled-coil domain containing 32 Ste5 PF11610.8 ORX95399.1 - 0.2 11.5 0.4 0.36 10.7 0.4 1.3 1 0 0 1 1 1 0 Scaffold protein Ste5, Fus3-binding region AflR PF08493.10 ORX95400.1 - 7.7e-17 61.7 2.4 1.1e-16 61.2 2.4 1.2 1 0 0 1 1 1 1 Aflatoxin regulatory protein Zn_clus PF00172.18 ORX95400.1 - 5.7e-09 36.0 8.5 1.3e-08 34.8 8.5 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Nitroreductase PF00881.24 ORX95401.1 - 8.5e-09 35.7 0.0 2.2e-08 34.4 0.0 1.6 1 1 0 1 1 1 1 Nitroreductase family Cas_csx3 PF09620.10 ORX95401.1 - 0.09 12.7 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_csx3) Sterol-sensing PF12349.8 ORX95402.1 - 7.3e-11 42.1 3.8 1.8e-10 40.8 0.3 2.9 2 1 1 3 3 3 1 Sterol-sensing domain of SREBP cleavage-activation FxsA PF04186.13 ORX95402.1 - 0.0091 16.1 3.0 0.022 14.9 0.3 2.7 3 0 0 3 3 3 1 FxsA cytoplasmic membrane protein Foamy_virus_ENV PF03408.14 ORX95402.1 - 0.18 9.6 0.0 0.27 9.0 0.0 1.1 1 0 0 1 1 1 0 Foamy virus envelope protein Patched PF02460.18 ORX95402.1 - 0.2 9.7 0.0 0.32 9.0 0.0 1.2 1 0 0 1 1 1 0 Patched family TPR_12 PF13424.6 ORX95403.1 - 9.7e-10 38.6 1.7 6.7e-05 23.1 0.1 4.2 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 ORX95403.1 - 1.8e-08 33.9 0.4 0.0073 16.3 0.0 5.9 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 ORX95403.1 - 1.1e-07 31.4 0.7 0.0051 16.9 0.0 5.3 7 1 0 7 7 6 1 Tetratricopeptide repeat TPR_14 PF13428.6 ORX95403.1 - 1.3e-07 31.9 13.6 0.52 11.3 0.2 5.4 3 2 3 6 6 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 ORX95403.1 - 1.9e-05 24.3 1.1 0.076 12.9 0.0 4.7 7 0 0 7 7 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 ORX95403.1 - 0.00014 22.4 12.4 0.44 11.2 0.0 4.4 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 ORX95403.1 - 0.00029 21.3 12.0 0.37 11.3 0.8 4.3 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 ORX95403.1 - 0.0013 18.9 0.1 5.8 7.5 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 ORX95403.1 - 0.003 17.7 0.1 4 7.7 0.0 3.1 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 ORX95403.1 - 0.0077 16.4 8.2 0.22 11.7 0.5 3.4 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 ORX95403.1 - 0.077 12.9 10.0 7.5 6.6 0.2 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 ORX95403.1 - 0.095 12.8 2.2 6.3 7.1 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_21 PF09976.9 ORX95403.1 - 0.14 11.8 2.9 1.2 8.8 0.0 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat-like domain RsbRD_N PF14361.6 ORX95403.1 - 0.14 12.8 3.6 1.6 9.5 0.2 3.1 3 0 0 3 3 3 0 RsbT co-antagonist protein rsbRD N-terminal domain TPR_11 PF13414.6 ORX95403.1 - 0.15 11.7 1.5 2.1 8.1 0.0 3.4 4 0 0 4 4 4 0 TPR repeat TPR_6 PF13174.6 ORX95403.1 - 0.24 12.1 8.4 52 4.8 0.0 5.4 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_20 PF14561.6 ORX95403.1 - 0.43 11.0 6.2 5.6 7.4 0.0 4.3 3 1 1 4 4 4 0 Tetratricopeptide repeat RWD PF05773.22 ORX95404.1 - 3.1e-25 88.7 1.8 3.1e-25 88.7 1.8 1.7 2 1 0 2 2 2 1 RWD domain DFRP_C PF16543.5 ORX95404.1 - 0.056 13.9 12.3 0.17 12.4 11.8 2.2 1 1 0 1 1 1 0 DRG Family Regulatory Proteins, Tma46 ketoacyl-synt PF00109.26 ORX95404.1 - 0.13 11.8 0.1 0.2 11.2 0.1 1.2 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain Jak1_Phl PF17887.1 ORX95404.1 - 0.51 10.3 4.1 0.99 9.4 4.1 1.4 1 0 0 1 1 1 0 Jak1 pleckstrin homology-like domain Atg14 PF10186.9 ORX95404.1 - 0.64 9.1 8.7 0.9 8.6 8.7 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Complex1_LYR PF05347.15 ORX95405.1 - 2.2e-09 37.2 0.1 4.3e-09 36.3 0.1 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 ORX95405.1 - 0.085 13.6 0.0 0.81 10.5 0.0 2.2 2 0 0 2 2 2 0 Complex1_LYR-like UQ_con PF00179.26 ORX95406.1 - 2.6e-15 56.3 0.0 2.9e-15 56.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 ORX95406.1 - 0.0039 17.4 0.0 0.0041 17.4 0.0 1.2 1 0 0 1 1 1 1 RWD domain DCB PF16213.5 ORX95407.1 - 1.7e-41 141.8 1.8 1.1e-40 139.2 1.8 2.5 1 0 0 1 1 1 1 Dimerisation and cyclophilin-binding domain of Mon2 Sec7_N PF12783.7 ORX95407.1 - 5.1e-40 137.0 3.9 6.4e-37 126.9 0.1 5.6 7 1 0 7 7 7 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Mon2_C PF16206.5 ORX95407.1 - 6e-20 71.0 0.8 2.2e-16 59.2 1.2 2.5 2 0 0 2 2 2 2 C-terminal region of Mon2 protein DUF1981 PF09324.10 ORX95407.1 - 9.7e-05 22.1 1.6 5.2 7.0 0.0 5.8 8 0 0 8 8 8 2 Domain of unknown function (DUF1981) Utp12 PF04003.12 ORX95407.1 - 0.24 11.7 1.6 1.9 8.9 0.1 3.3 3 0 0 3 3 3 0 Dip2/Utp12 Family CK_II_beta PF01214.18 ORX95408.1 - 8.8e-75 250.5 0.2 1.1e-74 250.2 0.2 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit DUF1754 PF08555.10 ORX95410.1 - 0.0049 17.6 19.6 0.25 12.2 16.9 2.4 2 0 0 2 2 2 2 Eukaryotic family of unknown function (DUF1754) RNA_polI_A34 PF08208.11 ORX95410.1 - 0.25 11.4 21.8 0.054 13.6 12.9 2.3 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 Presenilin PF01080.17 ORX95410.1 - 0.44 9.3 2.8 0.63 8.8 2.8 1.2 1 0 0 1 1 1 0 Presenilin Spot_14 PF07084.12 ORX95410.1 - 0.66 10.1 6.7 5.9 7.0 0.0 2.2 2 0 0 2 2 2 0 Thyroid hormone-inducible hepatic protein Spot 14 SLD3 PF08639.10 ORX95412.1 - 2.9e-138 462.0 6.6 4e-138 461.5 6.6 1.2 1 0 0 1 1 1 1 DNA replication regulator SLD3 L27_2 PF09045.10 ORX95412.1 - 0.13 12.3 0.0 0.74 9.8 0.0 2.4 3 0 0 3 3 3 0 L27_2 DUF3435 PF11917.8 ORX95446.1 - 1.8e-11 43.7 4.0 1.9e-11 43.6 4.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) zf-C2H2 PF00096.26 ORX95447.1 - 0.049 14.1 6.6 1.5 9.4 1.3 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORX95447.1 - 0.15 13.0 9.8 0.47 11.4 0.9 2.8 3 0 0 3 3 3 0 C2H2-type zinc finger Pkinase PF00069.25 ORX95448.1 - 0.00049 19.6 0.3 0.0007 19.0 0.3 1.3 1 1 0 1 1 1 1 Protein kinase domain HET PF06985.11 ORX95471.1 - 1.1e-09 38.7 0.0 1.5e-09 38.4 0.0 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.16 ORX95472.1 - 1.7e-47 162.0 31.8 1.7e-47 162.0 31.8 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORX95472.1 - 1.1e-14 54.2 5.8 1.1e-14 54.2 5.8 2.2 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 ORX95472.1 - 5.4e-09 35.8 4.3 5.4e-09 35.8 4.3 2.1 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB MFS_3 PF05977.13 ORX95472.1 - 7.3e-06 24.6 2.6 1.3e-05 23.8 2.4 1.4 1 1 0 1 1 1 1 Transmembrane secretion effector VIT1 PF01988.19 ORX95472.1 - 0.3 10.9 14.4 0.12 12.3 0.5 3.5 3 1 1 4 4 4 0 VIT family OATP PF03137.20 ORX95472.1 - 0.85 7.8 15.9 0.11 10.8 4.8 3.4 1 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Phage_holin_4_2 PF04020.13 ORX95473.1 - 6.6 7.5 7.0 3 8.6 0.5 2.6 2 0 0 2 2 2 0 Mycobacterial 4 TMS phage holin, superfamily IV NACHT PF05729.12 ORX95474.1 - 0.089 12.7 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 NACHT domain Spt20 PF12090.8 ORX95475.1 - 0.0082 15.8 1.6 0.01 15.5 1.6 1.2 1 0 0 1 1 1 1 Spt20 family Protamine_P2 PF00841.19 ORX95475.1 - 0.01 16.3 3.3 0.01 16.3 3.3 2.5 2 0 0 2 2 2 0 Sperm histone P2 Androgen_recep PF02166.16 ORX95475.1 - 0.084 11.7 3.5 0.16 10.8 3.5 1.4 1 0 0 1 1 1 0 Androgen receptor Med3 PF11593.8 ORX95475.1 - 2.1 7.4 12.2 4.6 6.3 12.2 1.5 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF5542 PF17696.1 ORX95475.1 - 4.2 7.6 7.9 38 4.5 0.0 3.1 2 1 1 3 3 3 0 Family of unknown function (DUF5542) Pkinase PF00069.25 ORX95477.1 - 2.9e-54 184.2 0.0 3.9e-54 183.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX95477.1 - 4.3e-32 111.4 0.0 5.3e-32 111.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 ORX95477.1 - 0.00019 21.5 0.0 0.00061 19.8 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 ORX95477.1 - 0.0052 16.2 0.0 0.0079 15.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 ORX95477.1 - 0.0096 15.3 0.0 0.023 14.0 0.0 1.7 1 1 1 2 2 2 1 Kinase-like Choline_kinase PF01633.20 ORX95477.1 - 0.18 11.4 0.0 0.29 10.7 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Haspin_kinase PF12330.8 ORX95477.1 - 0.19 10.7 0.4 0.29 10.0 0.0 1.5 2 0 0 2 2 2 0 Haspin like kinase domain HET PF06985.11 ORX95479.1 - 1.2e-35 123.0 1.7 2.9e-35 121.8 1.7 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DnaJ PF00226.31 ORX95494.1 - 3e-21 75.3 0.1 5.5e-21 74.5 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain Peptidase_M24 PF00557.24 ORX95495.1 - 1.1e-44 152.7 0.1 1.4e-44 152.3 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Pectinesterase PF01095.19 ORX95495.1 - 0.00042 19.1 0.0 0.00075 18.3 0.0 1.3 1 0 0 1 1 1 1 Pectinesterase YL1 PF05764.13 ORX95495.1 - 0.02 15.0 5.7 0.029 14.5 5.7 1.2 1 0 0 1 1 1 0 YL1 nuclear protein CDC45 PF02724.14 ORX95495.1 - 1.6 7.0 5.3 2.2 6.5 5.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Glyco_hydro_61 PF03443.14 ORX95496.1 - 4.1e-54 183.6 2.3 4.6e-54 183.5 2.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 MTTB PF06253.11 ORX95496.1 - 0.095 10.7 0.0 0.13 10.2 0.0 1.1 1 0 0 1 1 1 0 Trimethylamine methyltransferase (MTTB) TPR_12 PF13424.6 ORX95497.1 - 4.9e-09 36.3 6.1 0.041 14.2 0.0 5.7 5 0 0 5 5 5 3 Tetratricopeptide repeat SesA PF17107.5 ORX95497.1 - 2e-07 31.2 0.6 6.1e-07 29.7 0.6 1.9 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases NB-ARC PF00931.22 ORX95497.1 - 2.1e-06 27.1 0.0 4e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 ORX95497.1 - 3.9e-06 27.4 0.1 2e-05 25.0 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain ATPase_2 PF01637.18 ORX95497.1 - 0.039 13.9 0.0 0.082 12.8 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea NACHT PF05729.12 ORX95497.1 - 0.043 13.7 0.0 0.2 11.6 0.0 2.2 2 1 0 2 2 2 0 NACHT domain ResIII PF04851.15 ORX95497.1 - 0.16 12.0 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Imm1 PF14430.6 ORX95498.1 - 0.00094 19.8 0.0 0.0027 18.4 0.0 1.7 2 0 0 2 2 2 1 Immunity protein Imm1 zf-MYND PF01753.18 ORX95498.1 - 0.016 15.3 1.2 0.033 14.3 1.2 1.5 1 0 0 1 1 1 0 MYND finger DUF3884 PF13024.6 ORX95498.1 - 0.098 12.2 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3884) zf-MYND PF01753.18 ORX95499.1 - 4.3e-08 33.1 14.4 6.9e-08 32.5 14.4 1.3 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 ORX95499.1 - 1.1 9.7 11.6 2.1 8.7 11.6 1.5 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding PolC_DP2 PF03833.13 ORX95499.1 - 1.3 6.8 5.2 1.9 6.2 5.2 1.2 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-HIT PF04438.16 ORX95499.1 - 2.1 8.3 10.8 3.8 7.5 10.8 1.5 1 0 0 1 1 1 0 HIT zinc finger Methyltransf_16 PF10294.9 ORX95500.1 - 4.2e-42 143.8 0.0 5.6e-42 143.4 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 ORX95500.1 - 0.055 13.0 0.0 0.083 12.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Ammonium_transp PF00909.21 ORX95501.1 - 9e-71 238.7 21.3 1e-70 238.5 21.3 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family HET PF06985.11 ORX95502.1 - 2.2e-21 76.7 1.2 1.2e-19 71.1 0.0 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) LsmAD PF06741.13 ORX95503.1 - 6.9e-29 100.2 3.2 1.6e-28 99.1 3.2 1.7 1 0 0 1 1 1 1 LsmAD domain SM-ATX PF14438.6 ORX95503.1 - 2e-16 59.9 0.0 5.5e-16 58.5 0.0 1.8 1 0 0 1 1 1 1 Ataxin 2 SM domain AIP3 PF03915.13 ORX95504.1 - 1.3e-154 515.2 10.8 1.3e-154 515.2 10.8 1.7 2 0 0 2 2 2 1 Actin interacting protein 3 HET PF06985.11 ORX95505.1 - 3.5e-33 115.0 0.9 7.7e-33 113.9 0.9 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Mpp10 PF04006.12 ORX95506.1 - 1.4e-115 387.1 36.8 7.4e-115 384.7 36.8 1.8 1 1 0 1 1 1 1 Mpp10 protein 7kD_DNA_binding PF02294.18 ORX95507.1 - 0.026 14.5 0.2 0.068 13.2 0.0 1.7 2 0 0 2 2 2 0 7kD DNA-binding domain Peptidase_S74 PF13884.6 ORX95507.1 - 0.095 13.0 0.0 0.19 12.1 0.0 1.4 1 0 0 1 1 1 0 Chaperone of endosialidase Phage_min_tail PF05939.13 ORX95507.1 - 0.15 12.4 0.0 0.36 11.2 0.0 1.5 1 0 0 1 1 1 0 Phage minor tail protein Thioredoxin_6 PF13848.6 ORX95509.1 - 1.2e-14 54.6 0.0 5.9e-12 45.9 0.0 2.2 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin PF00085.20 ORX95509.1 - 0.00091 19.2 0.1 0.007 16.3 0.0 2.3 2 1 0 2 2 2 1 Thioredoxin Nup153 PF08604.10 ORX95509.1 - 0.011 14.6 0.1 0.024 13.4 0.0 1.4 1 1 0 1 1 1 0 Nucleoporin Nup153-like Nab6_mRNP_bdg PF10567.9 ORX95509.1 - 0.036 13.6 0.6 0.054 13.0 0.6 1.2 1 0 0 1 1 1 0 RNA-recognition motif 2OG-FeII_Oxy_3 PF13640.6 ORX95510.1 - 8.1e-13 49.1 0.0 1.2e-12 48.5 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF1451 PF07295.11 ORX95512.1 - 0.18 11.9 0.5 0.4 10.7 0.1 1.8 2 0 0 2 2 2 0 Zinc-ribbon containing domain UQ_con PF00179.26 ORX95513.1 - 1.9e-26 92.4 0.0 2.1e-26 92.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 ORX95513.1 - 0.00018 21.3 0.1 0.00031 20.6 0.1 1.4 1 1 0 1 1 1 1 UEV domain Lipid_DES PF08557.10 ORX95514.1 - 1.3e-17 62.9 0.5 2e-17 62.4 0.5 1.2 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) FA_desaturase PF00487.24 ORX95514.1 - 1.5e-12 47.9 11.1 2.1e-12 47.4 11.1 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Peptidase_M60 PF13402.6 ORX95514.1 - 0.0074 15.9 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase M60, enhancin and enhancin-like Chitin_synth_1 PF01644.17 ORX95533.1 - 2.4e-69 232.5 0.0 3.5e-69 231.9 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 ORX95533.1 - 6.6e-29 99.7 0.0 1.2e-28 98.8 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 ORX95533.1 - 1.8e-23 83.0 0.1 4.1e-19 68.6 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 ORX95533.1 - 2.7e-08 34.0 4.6 2.7e-08 34.0 4.6 2.8 3 1 0 3 3 3 1 Glycosyl transferase family group 2 DUF218 PF02698.17 ORX95534.1 - 4.3e-05 23.6 0.0 6.8e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 DUF218 domain HET PF06985.11 ORX95536.1 - 9.3e-20 71.5 7.1 1.1e-14 55.0 5.1 3.1 2 1 0 2 2 2 2 Heterokaryon incompatibility protein (HET) zf-RING_2 PF13639.6 ORX95538.1 - 4.1e-07 30.2 9.0 4.1e-07 30.2 9.0 2.0 1 1 1 2 2 2 2 Ring finger domain zf-rbx1 PF12678.7 ORX95538.1 - 2.9e-05 24.3 6.4 5.5e-05 23.4 6.4 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 ORX95538.1 - 0.00025 20.8 4.1 0.001 18.8 0.8 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 ORX95538.1 - 0.0016 18.3 11.5 0.025 14.4 9.5 2.8 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 ORX95538.1 - 0.0025 17.6 4.3 0.0025 17.6 4.3 2.0 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 ORX95538.1 - 0.0067 16.3 7.3 0.011 15.6 4.7 2.4 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORX95538.1 - 0.0088 16.0 6.4 0.015 15.3 6.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 ORX95538.1 - 0.029 14.5 3.3 0.029 14.5 3.3 2.3 2 1 1 3 3 3 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 ORX95538.1 - 0.074 13.2 6.8 0.18 12.0 6.2 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain zf-ANAPC11 PF12861.7 ORX95538.1 - 0.29 11.2 3.5 0.57 10.3 3.5 1.5 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 ORX95538.1 - 0.86 9.7 8.0 2.3 8.3 0.9 2.4 2 1 0 2 2 2 0 RING-type zinc-finger Zn_ribbon_17 PF17120.5 ORX95538.1 - 2.9 7.6 7.6 2.4 7.9 5.6 1.9 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type adh_short_C2 PF13561.6 ORX95539.1 - 1.2e-44 152.6 0.0 1.4e-44 152.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORX95539.1 - 5.2e-31 107.6 0.0 6.2e-31 107.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORX95539.1 - 5.5e-07 29.7 0.0 8.7e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 KR domain EMP24_GP25L PF01105.24 ORX95540.1 - 5e-41 140.6 0.0 6.1e-41 140.3 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD EzrA PF06160.12 ORX95540.1 - 0.22 9.7 0.1 0.3 9.2 0.1 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA RibD_C PF01872.17 ORX95542.1 - 8.2e-33 113.9 0.0 9.6e-33 113.7 0.0 1.0 1 0 0 1 1 1 1 RibD C-terminal domain UQ_con PF00179.26 ORX95543.1 - 2.2e-38 131.0 0.0 2.9e-38 130.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme IlvN PF07991.12 ORX95544.1 - 1.3e-45 155.0 0.0 2.3e-45 154.1 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 ORX95544.1 - 2.9e-39 134.6 0.0 4.5e-39 134.0 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain IF-2B PF01008.17 ORX95546.1 - 3.7e-29 101.8 0.1 4.8e-29 101.4 0.1 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family CPG4 PF15481.6 ORX95546.1 - 0.024 15.3 0.5 0.052 14.2 0.5 1.6 1 1 0 1 1 1 0 Chondroitin proteoglycan 4 TilS_C PF11734.8 ORX95546.1 - 0.034 13.6 0.0 0.079 12.4 0.0 1.6 1 0 0 1 1 1 0 TilS substrate C-terminal domain SopA_C PF13979.6 ORX95546.1 - 0.061 13.1 0.2 0.11 12.2 0.2 1.5 1 0 0 1 1 1 0 SopA-like catalytic domain tRNA-Thr_ED PF08915.11 ORX95546.1 - 0.18 11.9 0.0 1.6 8.8 0.0 2.2 2 0 0 2 2 2 0 Archaea-specific editing domain of threonyl-tRNA synthetase AAA PF00004.29 ORX95550.1 - 1.6e-11 44.8 0.9 1.2e-10 41.9 0.2 2.7 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 ORX95550.1 - 0.00094 19.6 0.0 0.0014 19.0 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 ORX95550.1 - 0.0045 17.3 0.2 0.096 13.0 0.1 2.6 3 0 0 3 3 3 1 AAA domain Zot PF05707.12 ORX95550.1 - 0.019 14.6 0.0 5.3 6.6 0.0 2.3 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) AAA_11 PF13086.6 ORX95550.1 - 0.045 13.5 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 ORX95550.1 - 0.055 12.8 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI T2SSE PF00437.20 ORX95550.1 - 0.079 12.0 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Cutinase PF01083.22 ORX95596.1 - 1.9e-21 76.8 0.4 2.3e-21 76.5 0.4 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 ORX95596.1 - 9.6e-06 25.3 0.0 1.3e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 PE-PPE domain VirJ PF06057.11 ORX95596.1 - 0.0011 18.9 0.0 0.0015 18.4 0.0 1.2 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) Thioesterase PF00975.20 ORX95596.1 - 0.0037 17.4 0.0 0.0048 17.0 0.0 1.1 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_2 PF02230.16 ORX95596.1 - 0.042 13.7 0.0 0.061 13.1 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 ORX95596.1 - 0.18 11.1 0.0 0.29 10.4 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 MFS_1 PF07690.16 ORX95598.1 - 7.1e-23 81.1 23.5 1.8e-22 79.8 23.5 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 ORX95598.1 - 0.00057 19.3 1.1 0.00092 18.6 1.1 1.2 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB UPRTase PF14681.6 ORX95600.1 - 1.2e-38 132.7 0.3 2.2e-38 131.8 0.3 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase HAD PF12710.7 ORX95600.1 - 1.5e-19 71.1 0.1 3.1e-19 70.1 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase AAA_17 PF13207.6 ORX95600.1 - 4.6e-18 66.0 0.0 9.2e-18 65.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain KAP_NTPase PF07693.14 ORX95600.1 - 1.7e-05 24.2 0.0 4.9e-05 22.7 0.0 1.7 2 0 0 2 2 2 1 KAP family P-loop domain PRTase_2 PF15609.6 ORX95600.1 - 2.5e-05 23.9 0.4 0.0022 17.5 0.1 2.4 2 0 0 2 2 2 1 Phosphoribosyl transferase AAA_33 PF13671.6 ORX95600.1 - 3.1e-05 24.1 0.0 7e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ORX95600.1 - 7.5e-05 23.2 0.1 0.00025 21.5 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain Pribosyltran PF00156.27 ORX95600.1 - 0.0026 17.3 0.6 0.0026 17.3 0.6 2.5 2 1 0 2 2 2 1 Phosphoribosyl transferase domain AAA_14 PF13173.6 ORX95600.1 - 0.0028 17.7 0.0 0.71 9.9 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_24 PF13479.6 ORX95600.1 - 0.006 16.3 0.0 0.032 14.0 0.0 2.1 2 1 1 3 3 3 1 AAA domain AAA_22 PF13401.6 ORX95600.1 - 0.0066 16.7 0.0 0.025 14.8 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 ORX95600.1 - 0.0074 16.8 0.0 0.021 15.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 ORX95600.1 - 0.012 14.9 0.1 0.44 9.8 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin AAA PF00004.29 ORX95600.1 - 0.024 15.1 0.0 0.061 13.8 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MeaB PF03308.16 ORX95600.1 - 0.025 13.5 0.0 0.05 12.6 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB FERM_F1 PF18379.1 ORX95600.1 - 0.026 14.5 0.1 0.086 12.9 0.1 1.8 2 0 0 2 2 2 0 FERM F1 ubiquitin-like domain DUF4745 PF15923.5 ORX95600.1 - 0.065 13.2 0.0 11 6.0 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4745) Hydrolase PF00702.26 ORX95600.1 - 0.075 13.3 0.0 0.15 12.4 0.0 1.6 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase NACHT PF05729.12 ORX95600.1 - 0.084 12.8 0.1 0.35 10.8 0.0 2.0 2 0 0 2 2 2 0 NACHT domain NB-ARC PF00931.22 ORX95600.1 - 0.093 11.9 0.0 0.27 10.4 0.0 1.7 1 0 0 1 1 1 0 NB-ARC domain FlgT_N PF16548.5 ORX95600.1 - 0.097 13.3 0.0 0.33 11.5 0.0 2.0 1 0 0 1 1 1 0 Flagellar assembly protein T, N-terminal domain PIF1 PF05970.14 ORX95600.1 - 0.097 11.8 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase Torsin PF06309.11 ORX95600.1 - 0.12 12.5 0.1 1.2 9.3 0.0 2.5 2 0 0 2 2 2 0 Torsin ABC_tran PF00005.27 ORX95600.1 - 0.12 12.9 0.0 0.36 11.3 0.0 1.7 1 0 0 1 1 1 0 ABC transporter Hydrolase_3 PF08282.12 ORX95600.1 - 0.16 11.7 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase AAA_30 PF13604.6 ORX95600.1 - 0.35 10.5 1.9 2.1 8.0 0.0 2.8 3 0 0 3 3 3 0 AAA domain Ribonucleas_3_3 PF14622.6 ORX95601.1 - 0.00011 22.4 0.0 0.00021 21.4 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease-III-like Stork_head PF10264.9 ORX95603.1 - 0.012 15.8 0.0 0.015 15.5 0.0 1.2 1 0 0 1 1 1 0 Winged helix Storkhead-box1 domain WD40 PF00400.32 ORX95604.1 - 2.2e-17 63.1 6.0 0.0022 18.8 0.1 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat PQQ_2 PF13360.6 ORX95604.1 - 0.00054 19.6 0.0 0.2 11.2 0.0 2.9 2 1 1 3 3 3 2 PQQ-like domain WD40_like PF17005.5 ORX95604.1 - 0.00089 18.7 0.0 0.12 11.7 0.0 3.0 2 1 0 2 2 2 1 WD40-like domain ANAPC4_WD40 PF12894.7 ORX95604.1 - 0.017 15.4 0.1 1.4 9.3 0.0 3.4 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 ORX95604.1 - 0.091 13.3 1.0 3.6 8.2 0.1 3.5 3 0 0 3 3 3 0 PQQ-like domain OTT_1508_deam PF14441.6 ORX95605.1 - 5e-16 58.5 0.1 1.1e-15 57.3 0.1 1.6 1 0 0 1 1 1 1 OTT_1508-like deaminase TruB_N PF01509.18 ORX95606.1 - 1.7e-40 138.8 0.1 4.5e-40 137.4 0.0 1.7 2 0 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 ORX95606.1 - 0.017 15.3 0.0 0.033 14.3 0.0 1.5 1 0 0 1 1 1 0 tRNA pseudouridylate synthase B C-terminal domain Fungal_trans PF04082.18 ORX95656.1 - 1.6e-24 86.3 2.6 2.7e-24 85.6 2.6 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORX95656.1 - 3.2e-05 24.0 1.5 5.8e-05 23.1 1.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ECH_1 PF00378.20 ORX95657.1 - 3.9e-23 82.1 0.0 4.8e-23 81.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ORX95657.1 - 2.3e-15 56.9 0.0 2.6e-15 56.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 ORX95658.1 - 1.5e-14 53.9 0.0 2.1e-12 46.9 0.0 2.0 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ORX95658.1 - 1.1e-05 25.2 0.0 6.2e-05 22.6 0.0 1.8 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase Fungal_trans PF04082.18 ORX95659.1 - 6e-06 25.5 0.0 8.8e-06 24.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain AMP-binding PF00501.28 ORX95660.1 - 2.8e-43 148.1 0.1 4.8e-29 101.2 0.0 2.1 1 1 1 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 ORX95660.1 - 7e-10 39.7 0.1 3.3e-09 37.6 0.1 2.2 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain eIF-5a PF01287.20 ORX95660.1 - 0.033 14.3 0.0 0.071 13.2 0.0 1.6 1 0 0 1 1 1 0 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold IMPDH PF00478.25 ORX95660.1 - 0.034 13.2 0.3 0.062 12.3 0.3 1.4 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain MFS_1 PF07690.16 ORX95661.1 - 5.2e-09 35.5 16.8 2e-08 33.6 16.8 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily adh_short_C2 PF13561.6 ORX95663.1 - 1.1e-56 192.1 0.3 1.6e-56 191.5 0.3 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORX95663.1 - 1.2e-41 142.3 1.4 1.7e-41 141.9 1.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase DLH PF01738.18 ORX95663.1 - 1.7e-20 73.5 0.0 3e-20 72.7 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 ORX95663.1 - 0.058 12.9 0.1 0.15 11.5 0.1 1.7 1 0 0 1 1 1 0 Prolyl oligopeptidase family 3HCDH_N PF02737.18 ORX95663.1 - 0.13 12.2 0.3 0.5 10.2 0.3 1.8 1 1 1 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MFS_1 PF07690.16 ORX95664.1 - 1.4e-31 109.7 26.4 1.7e-31 109.4 26.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 ORX95664.1 - 0.0032 16.4 15.5 0.0057 15.5 13.4 1.9 1 1 1 2 2 2 1 MFS_1 like family DUF676 PF05057.14 ORX95666.1 - 0.0013 18.3 0.0 0.0025 17.4 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 ORX95666.1 - 0.0015 19.2 0.0 0.0019 18.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.13 ORX95666.1 - 0.19 11.6 0.0 0.33 10.8 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase WD40 PF00400.32 ORX95667.1 - 2.7e-41 138.8 25.4 3.7e-11 43.4 0.3 8.8 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX95667.1 - 6.4e-14 52.0 8.2 0.0021 18.3 0.0 6.7 1 1 5 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain NACHT PF05729.12 ORX95667.1 - 2.5e-10 40.5 0.0 4.8e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 ORX95667.1 - 2.2e-06 28.2 0.0 5.5e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain WD40_like PF17005.5 ORX95667.1 - 2.7e-06 26.9 2.8 0.3 10.4 0.1 4.2 5 0 0 5 5 5 2 WD40-like domain Cytidylate_kin PF02224.18 ORX95667.1 - 0.001 18.8 0.1 0.24 11.1 0.0 2.3 2 0 0 2 2 2 1 Cytidylate kinase AAA_18 PF13238.6 ORX95667.1 - 0.0013 19.3 0.1 0.0046 17.5 0.1 2.0 1 1 0 1 1 1 1 AAA domain Cytochrom_D1 PF02239.16 ORX95667.1 - 0.0019 16.8 2.3 0.21 10.1 0.3 2.6 2 1 0 2 2 2 2 Cytochrome D1 heme domain Frtz PF11768.8 ORX95667.1 - 0.012 14.0 0.2 0.2 9.9 0.1 2.2 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz AAA_22 PF13401.6 ORX95667.1 - 0.012 15.8 0.1 0.099 12.9 0.0 2.4 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 ORX95667.1 - 0.029 14.7 0.1 0.095 13.1 0.1 1.8 1 1 0 2 2 1 0 RNA helicase APS_kinase PF01583.20 ORX95667.1 - 0.033 14.1 0.1 0.067 13.1 0.1 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase TsaE PF02367.17 ORX95667.1 - 0.05 13.6 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ParA PF10609.9 ORX95667.1 - 0.051 13.0 0.1 0.099 12.1 0.1 1.4 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase AAA_33 PF13671.6 ORX95667.1 - 0.059 13.5 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain CbiA PF01656.23 ORX95667.1 - 0.065 13.3 0.2 0.21 11.7 0.2 1.9 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_30 PF13604.6 ORX95667.1 - 0.08 12.7 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 ORX95667.1 - 0.11 12.9 0.0 0.26 11.7 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PIF1 PF05970.14 ORX95667.1 - 0.12 11.6 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase Ge1_WD40 PF16529.5 ORX95667.1 - 0.55 9.1 7.9 31 3.4 3.8 3.8 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein KAP_NTPase PF07693.14 ORX95667.1 - 0.78 8.9 3.0 6.1 6.0 0.3 2.3 1 1 1 2 2 2 0 KAP family P-loop domain SET PF00856.28 ORX95668.1 - 5e-11 43.3 1.3 2.8e-10 40.8 0.5 2.3 2 1 0 2 2 2 1 SET domain TPR_MalT PF17874.1 ORX95668.1 - 0.0018 17.7 0.7 0.0043 16.5 0.0 1.8 2 0 0 2 2 2 1 MalT-like TPR region p450 PF00067.22 ORX95688.1 - 3.3e-43 148.1 0.0 4.2e-43 147.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Penicillinase_R PF03965.16 ORX95690.1 - 0.06 13.7 0.1 0.13 12.6 0.1 1.5 1 0 0 1 1 1 0 Penicillinase repressor Glyco_hydro_17 PF00332.18 ORX95691.1 - 1.1e-05 25.2 0.4 1.4e-05 24.9 0.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 Glyco_hydro_28 PF00295.17 ORX95694.1 - 3.5e-44 151.2 7.2 2.2e-43 148.6 7.2 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 Thioredoxin PF00085.20 ORX95695.1 - 6e-08 32.6 0.0 7.5e-08 32.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_9 PF14595.6 ORX95695.1 - 0.0023 17.7 0.1 0.077 12.8 0.1 2.0 2 0 0 2 2 2 1 Thioredoxin DUF953 PF06110.11 ORX95695.1 - 0.0091 15.6 0.1 3 7.5 0.0 2.2 2 0 0 2 2 2 2 Eukaryotic protein of unknown function (DUF953) Thioredoxin_3 PF13192.6 ORX95695.1 - 0.044 13.8 0.0 0.08 13.0 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin domain Thioredoxin_2 PF13098.6 ORX95695.1 - 0.062 13.8 0.0 1.3 9.5 0.0 2.1 1 1 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_7 PF13899.6 ORX95695.1 - 0.12 12.5 0.1 0.2 11.8 0.1 1.3 1 0 0 1 1 1 0 Thioredoxin-like Peptidase_C48 PF02902.19 ORX95697.1 - 6.5e-06 26.1 2.9 0.0033 17.3 0.0 2.6 3 0 0 3 3 3 2 Ulp1 protease family, C-terminal catalytic domain Alpha-mann_mid PF09261.11 ORX95698.1 - 0.18 11.9 0.3 0.39 10.9 0.3 1.6 1 0 0 1 1 1 0 Alpha mannosidase middle domain DUF724 PF05266.14 ORX95698.1 - 1.3 8.8 4.0 1.9 8.3 4.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Far-17a_AIG1 PF04750.14 ORX95699.1 - 0.0046 16.3 20.3 0.0074 15.6 20.3 1.3 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein DHHC PF01529.20 ORX95699.1 - 0.013 15.6 3.0 0.013 15.6 3.0 2.6 2 1 1 3 3 3 0 DHHC palmitoyltransferase DUF2700 PF10912.8 ORX95699.1 - 2.7 8.0 10.9 0.26 11.3 5.5 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2700) DUF4834 PF16118.5 ORX95699.1 - 4 8.5 4.2 7.4 7.6 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DUF2070 PF09843.9 ORX95699.1 - 4.2 5.5 16.1 5.5 5.2 16.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) RNase_H2_suC PF08615.11 ORX95701.1 - 1e-27 97.0 0.0 1.2e-27 96.8 0.0 1.0 1 0 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) CMAS PF02353.20 ORX95702.1 - 8.3e-68 228.6 0.1 1.4e-66 224.7 0.1 2.0 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 ORX95702.1 - 1.1e-10 42.1 0.0 2.1e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORX95702.1 - 2.2e-09 37.8 0.0 4.5e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORX95702.1 - 4.1e-08 33.2 0.0 6.4e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORX95702.1 - 6.8e-07 29.2 0.0 1.4e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORX95702.1 - 1.1e-05 26.1 0.0 2.5e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 ORX95702.1 - 0.00026 20.8 0.0 0.00043 20.1 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF938 PF06080.12 ORX95702.1 - 0.0026 17.5 0.0 0.0059 16.4 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_3 PF01596.17 ORX95702.1 - 0.02 14.1 0.0 0.033 13.3 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase RrnaAD PF00398.20 ORX95702.1 - 0.023 13.8 0.0 0.043 12.9 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase DOT1 PF08123.13 ORX95702.1 - 0.043 13.3 0.0 0.091 12.3 0.0 1.5 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_16 PF10294.9 ORX95702.1 - 0.049 13.4 0.0 0.078 12.7 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Tautomerase_3 PF14832.6 ORX95703.1 - 1.8e-09 37.9 0.1 4.4e-09 36.7 0.1 1.6 1 1 0 1 1 1 1 Putative oxalocrotonate tautomerase enzyme His_Phos_1 PF00300.22 ORX95704.1 - 2.6e-20 72.9 0.0 3.6e-20 72.5 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Renin_r PF07850.14 ORX95705.1 - 9.5 6.9 7.9 1.2 9.8 0.2 2.8 3 0 0 3 3 3 0 Renin receptor-like protein HET PF06985.11 ORX95707.1 - 6.7e-25 88.1 0.0 1.1e-24 87.4 0.0 1.3 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MOZ_SAS PF01853.18 ORX95708.1 - 1e-81 272.9 0.0 1.5e-81 272.3 0.0 1.3 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.8 ORX95708.1 - 2.8e-23 81.5 0.3 6.2e-23 80.4 0.3 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain zf-MYST PF17772.1 ORX95708.1 - 8.5e-23 79.7 1.2 1.8e-22 78.7 1.2 1.6 1 0 0 1 1 1 1 MYST family zinc finger domain Acetyltransf_7 PF13508.7 ORX95708.1 - 0.0016 18.8 0.0 0.0033 17.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Condensation PF00668.20 ORX95708.1 - 0.057 12.1 0.1 0.1 11.3 0.1 1.3 1 0 0 1 1 1 0 Condensation domain Acetyltransf_1 PF00583.25 ORX95708.1 - 0.069 13.4 0.0 0.17 12.1 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family RNase_T PF00929.24 ORX95709.1 - 9e-14 52.3 0.0 1.9e-11 44.8 0.0 2.3 1 1 1 2 2 2 2 Exonuclease Aldo_ket_red PF00248.21 ORX95710.1 - 6.9e-66 222.4 0.0 7.9e-66 222.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DNA_pol3_tau_4 PF12168.8 ORX95710.1 - 0.047 14.2 0.9 0.089 13.4 0.9 1.4 1 0 0 1 1 1 0 DNA polymerase III subunits tau domain IV DnaB-binding Paramecium_SA PF01508.16 ORX95725.1 - 3.5 8.1 43.1 7.9 7.0 18.2 3.3 1 1 1 2 2 2 0 Paramecium surface antigen domain HupF_HypC PF01455.18 ORX95726.1 - 0.081 13.1 4.9 0.2 11.8 0.6 2.2 2 0 0 2 2 2 0 HupF/HypC family FAD_binding_4 PF01565.23 ORX95729.1 - 3.1e-18 65.8 0.8 4.9e-18 65.2 0.8 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 ORX95729.1 - 0.14 12.3 0.1 0.32 11.1 0.1 1.6 1 0 0 1 1 1 0 Berberine and berberine like RTA1 PF04479.13 ORX95730.1 - 1.3e-56 191.5 12.6 1.6e-56 191.2 12.6 1.1 1 0 0 1 1 1 1 RTA1 like protein DUF3094 PF11293.8 ORX95730.1 - 0.85 9.4 2.6 12 5.7 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3094) DctQ PF04290.12 ORX95730.1 - 6.4 6.7 13.9 6.1 6.8 6.5 2.4 2 0 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component Zn_clus PF00172.18 ORX95731.1 - 1.1e-09 38.3 7.8 2e-09 37.4 7.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 ORX95731.1 - 1.8e-08 33.6 2.9 2.1e-08 33.4 1.8 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain RTA1 PF04479.13 ORX95732.1 - 8.8e-71 237.8 9.5 8.8e-71 237.8 9.5 1.5 2 0 0 2 2 2 1 RTA1 like protein Tax PF02959.16 ORX95732.1 - 0.12 11.8 0.3 0.49 9.8 0.0 2.1 3 0 0 3 3 3 0 HTLV Tax HEAT_2 PF13646.6 ORX95786.1 - 1.6e-30 105.3 4.9 1.5e-14 54.2 1.0 3.9 2 2 2 4 4 4 2 HEAT repeats HEAT_PBS PF03130.16 ORX95786.1 - 2.7e-21 74.0 0.1 0.0028 18.2 0.0 6.5 6 0 0 6 6 6 5 PBS lyase HEAT-like repeat HEAT PF02985.22 ORX95786.1 - 9.8e-07 28.5 2.2 1.8 9.0 0.0 5.9 7 0 0 7 7 7 2 HEAT repeat HEAT_EZ PF13513.6 ORX95786.1 - 3.7e-06 27.3 5.0 0.61 10.6 0.0 5.8 4 2 3 7 7 7 1 HEAT-like repeat Arm PF00514.23 ORX95786.1 - 0.003 17.6 0.0 0.48 10.5 0.0 3.1 2 0 0 2 2 2 1 Armadillo/beta-catenin-like repeat PUB_1 PF18486.1 ORX95786.1 - 0.11 12.4 0.7 0.35 10.7 0.1 2.2 2 0 0 2 2 2 0 PNGase/UBA- or UBX-containing domain Cnd1 PF12717.7 ORX95786.1 - 0.18 11.8 0.0 31 4.5 0.0 3.4 2 2 2 4 4 4 0 non-SMC mitotic condensation complex subunit 1 TFIIS_C PF01096.18 ORX95787.1 - 2.3e-14 52.9 4.0 2.3e-14 52.9 4.0 3.1 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 ORX95787.1 - 1e-05 25.3 0.3 1e-05 25.3 0.3 2.8 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit zinc_ribbon_2 PF13240.6 ORX95787.1 - 0.002 17.8 8.3 0.79 9.5 0.5 3.8 4 0 0 4 4 4 2 zinc-ribbon domain UCH_1 PF13423.6 ORX95787.1 - 0.0037 16.9 1.9 0.004 16.8 1.9 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-C2H2_12 PF18658.1 ORX95787.1 - 0.03 13.9 0.7 0.093 12.3 0.1 2.0 1 1 1 2 2 2 0 Zinc-finger C2H2-type OrfB_Zn_ribbon PF07282.11 ORX95787.1 - 0.07 13.1 11.9 3.4 7.6 5.4 3.1 3 1 0 3 3 3 0 Putative transposase DNA-binding domain Zn-ribbon_8 PF09723.10 ORX95787.1 - 0.39 10.9 8.9 0.51 10.5 0.5 3.0 3 0 0 3 3 3 0 Zinc ribbon domain zf-trcl PF13451.6 ORX95787.1 - 0.42 10.6 7.0 12 5.8 0.3 3.3 3 0 0 3 3 3 0 Probable zinc-ribbon domain RecR PF02132.15 ORX95787.1 - 0.5 10.0 4.8 0.98 9.0 1.3 2.7 2 1 0 2 2 2 0 RecR protein Cytochrom_c3_2 PF14537.6 ORX95787.1 - 1.9 9.0 10.5 18 5.9 10.5 2.2 1 1 0 1 1 1 0 Cytochrome c3 DZR PF12773.7 ORX95787.1 - 2.1 8.4 11.8 1.4e+02 2.6 12.1 2.6 1 1 0 1 1 1 0 Double zinc ribbon Nipped-B_C PF12830.7 ORX95788.1 - 1.7e-40 139.0 1.4 1.5e-39 135.9 0.2 3.2 3 1 0 3 3 3 1 Sister chromatid cohesion C-terminus Adaptin_N PF01602.20 ORX95788.1 - 2.9e-06 26.1 0.3 9.8e-05 21.1 0.1 2.5 2 0 0 2 2 2 1 Adaptin N terminal region Cnd1 PF12717.7 ORX95788.1 - 6.7e-06 26.2 0.1 0.00059 19.9 0.0 3.7 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 ORX95788.1 - 0.0027 18.1 0.6 0.46 10.9 0.0 4.2 3 1 1 4 4 4 1 HEAT repeats MMS22L_C PF14911.6 ORX95788.1 - 0.08 12.0 0.2 0.17 10.9 0.2 1.5 1 0 0 1 1 1 0 S-phase genomic integrity recombination mediator, C-terminal FAM176 PF14851.6 ORX95788.1 - 5.3 6.7 6.0 0.92 9.2 0.2 2.3 2 0 0 2 2 2 0 FAM176 family Ank_2 PF12796.7 ORX95789.1 - 9.3e-24 83.8 1.5 5.1e-13 49.4 0.3 2.8 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ORX95789.1 - 2.3e-20 70.5 3.9 0.00092 19.5 0.0 5.1 5 0 0 5 5 5 5 Ankyrin repeat Ank PF00023.30 ORX95789.1 - 3e-18 65.3 6.0 2.4e-05 24.6 0.1 5.1 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.6 ORX95789.1 - 3.2e-18 65.8 3.3 6.3e-09 36.2 0.1 4.0 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 ORX95789.1 - 5.6e-18 64.8 6.2 1.1e-06 28.8 0.1 5.0 2 2 3 5 5 5 5 Ankyrin repeats (many copies) DnaJ PF00226.31 ORX95790.1 - 1.2e-10 41.3 0.1 2.1e-10 40.6 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain SOG2 PF10428.9 ORX95790.1 - 1.3 8.1 10.5 1.7 7.7 10.5 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Wyosine_form PF08608.12 ORX95791.1 - 2.8e-21 75.6 0.0 6.6e-21 74.4 0.0 1.7 1 0 0 1 1 1 1 Wyosine base formation Radical_SAM PF04055.21 ORX95791.1 - 2.5e-18 67.0 0.0 6.5e-18 65.7 0.0 1.7 1 1 0 1 1 1 1 Radical SAM superfamily Flavodoxin_1 PF00258.25 ORX95791.1 - 3.5e-09 37.0 0.0 1.9e-07 31.4 0.0 2.5 1 1 0 1 1 1 1 Flavodoxin PAPS_reduct PF01507.19 ORX95792.1 - 3.5e-29 102.1 0.0 8.8e-20 71.4 0.0 2.4 1 1 1 2 2 2 2 Phosphoadenosine phosphosulfate reductase family NIR_SIR PF01077.22 ORX95793.1 - 2e-52 176.9 0.0 1.9e-46 157.5 0.0 2.4 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 ORX95793.1 - 1.9e-29 101.3 0.0 1.2e-13 50.7 0.0 2.7 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.25 ORX95793.1 - 3.6e-29 101.8 0.0 9.5e-29 100.4 0.0 1.8 1 0 0 1 1 1 1 Flavodoxin POR_N PF01855.19 ORX95793.1 - 5.1e-10 39.5 0.3 1.1e-09 38.4 0.3 1.5 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg TauD PF02668.16 ORX95795.1 - 3.2e-54 184.5 0.3 4.6e-54 184.0 0.3 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Glyco_transf_15 PF01793.16 ORX95796.1 - 4.2e-131 437.0 9.8 5.3e-131 436.7 9.8 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase EGF_3 PF12947.7 ORX95796.1 - 0.23 11.7 2.6 0.44 10.8 2.6 1.4 1 0 0 1 1 1 0 EGF domain PAT1 PF09770.9 ORX95797.1 - 0 1160.1 14.8 0 1159.9 14.8 1.0 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Syja_N PF02383.18 ORX95799.1 - 9.8e-78 261.7 0.0 1.5e-77 261.0 0.0 1.3 1 0 0 1 1 1 1 SacI homology domain MFS_1 PF07690.16 ORX95800.1 - 2.8e-32 112.0 13.8 2.8e-32 112.0 13.8 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3915 PF13054.6 ORX95801.1 - 0.43 10.6 1.8 0.57 10.2 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) LapA_dom PF06305.11 ORX95801.1 - 2 8.3 3.6 3.5 7.5 3.6 1.4 1 1 0 1 1 1 0 Lipopolysaccharide assembly protein A domain DUF2345 PF10106.9 ORX95827.1 - 0.057 13.3 0.0 0.071 13.0 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2345) Helo_like_N PF17111.5 ORX95829.1 - 1.1e-05 24.9 0.5 1.9e-05 24.1 0.5 1.3 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins Zn_clus PF00172.18 ORX95830.1 - 6.6e-07 29.3 9.9 6.6e-07 29.3 9.9 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 ORX95831.1 - 1.3e-37 129.6 48.6 1.3e-37 129.6 48.6 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORX95831.1 - 4.1e-07 29.2 18.2 4.1e-07 29.2 18.2 3.5 2 2 2 4 4 4 2 Sugar (and other) transporter Sacchrp_dh_NADP PF03435.18 ORX95834.1 - 1e-13 51.7 0.3 1.9e-13 50.8 0.3 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain p450 PF00067.22 ORX95834.1 - 5.7e-10 38.5 0.0 7.9e-10 38.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 NAD_binding_10 PF13460.6 ORX95834.1 - 0.018 15.0 0.2 0.032 14.1 0.2 1.4 1 0 0 1 1 1 0 NAD(P)H-binding Glyco_hydro2_C5 PF18565.1 ORX95835.1 - 4.6e-28 97.1 0.3 9.7e-28 96.0 0.3 1.6 1 0 0 1 1 1 1 Glycoside hydrolase family 2 C-terminal domain 5 Glyco_hydro_2_C PF02836.17 ORX95835.1 - 8.3e-26 90.8 0.0 3e-25 89.0 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain DUF4982 PF16355.5 ORX95835.1 - 1.7e-23 82.3 0.3 4.7e-23 80.9 0.3 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4982) Glyco_hydro_2_N PF02837.18 ORX95835.1 - 1.4e-18 67.3 0.1 1.2e-17 64.4 0.0 2.6 3 0 0 3 3 3 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.21 ORX95835.1 - 9.5e-18 64.9 0.2 2.1e-17 63.8 0.2 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.6 ORX95835.1 - 2.7e-06 27.9 0.2 0.00015 22.3 0.0 3.3 3 0 0 3 3 3 1 Beta-galactosidase jelly roll domain PEN-2 PF10251.9 ORX95837.1 - 0.71 10.3 9.3 0.31 11.5 6.2 2.1 2 0 0 2 2 2 0 Presenilin enhancer-2 subunit of gamma secretase BTB PF00651.31 ORX95866.1 - 6.1e-07 29.6 0.0 8e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 ORX95867.1 - 6e-11 42.6 0.0 8.6e-11 42.0 0.0 1.3 1 1 0 1 1 1 1 BTB/POZ domain UPF0154 PF03672.13 ORX95867.1 - 0.062 13.3 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) adh_short PF00106.25 ORX95868.1 - 4.1e-41 140.6 0.0 5.6e-41 140.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORX95868.1 - 2.7e-27 95.9 0.0 3.5e-27 95.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORX95868.1 - 3.3e-12 46.7 0.0 4.7e-12 46.2 0.0 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 ORX95868.1 - 1.2e-05 24.9 0.0 1.5e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 ORX95868.1 - 4.3e-05 23.1 0.1 0.00014 21.4 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 ORX95868.1 - 0.00063 19.0 0.0 0.00087 18.5 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 ORX95868.1 - 0.023 15.0 0.1 0.034 14.4 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain RmlD_sub_bind PF04321.17 ORX95868.1 - 0.033 13.3 0.0 0.043 12.9 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain NPBW PF15180.6 ORX95869.1 - 0.11 12.3 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Neuropeptides B and W GH131_N PF18271.1 ORX95871.1 - 4.1e-79 265.9 0.3 4.6e-79 265.7 0.3 1.0 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain FluMu_N PF17891.1 ORX95871.1 - 0.15 11.9 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 Mu-like prophage FluMu N-terminal domain Polysacc_deac_1 PF01522.21 ORX95872.1 - 8.2e-15 54.8 0.0 2e-14 53.5 0.0 1.6 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 ORX95872.1 - 0.0067 16.1 0.0 0.015 15.0 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) Polysacc_deac_2 PF04748.13 ORX95872.1 - 0.051 12.8 0.0 0.17 11.1 0.0 1.9 2 0 0 2 2 2 0 Divergent polysaccharide deacetylase NTP_transf_9 PF04248.12 ORX95874.1 - 1.9e-40 136.7 2.3 9.6e-33 111.9 1.1 2.3 2 1 0 2 2 2 2 Domain of unknown function (DUF427) TauD PF02668.16 ORX95875.1 - 3.1e-36 125.6 0.1 5.6e-36 124.7 0.1 1.4 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family SF-assemblin PF06705.11 ORX95876.1 - 0.67 9.2 15.5 1.4 8.2 15.4 1.5 1 1 0 1 1 1 0 SF-assemblin/beta giardin Exonuc_VII_L PF02601.15 ORX95876.1 - 2.4 7.7 12.6 1.1 8.8 9.7 1.9 2 0 0 2 2 2 0 Exonuclease VII, large subunit V_ATPase_I PF01496.19 ORX95876.1 - 2.7 5.8 8.6 3.8 5.3 8.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spc24 PF08286.11 ORX95876.1 - 3.3 8.0 16.0 5.8 7.2 3.7 3.6 2 1 2 4 4 4 0 Spc24 subunit of Ndc80 DUF4407 PF14362.6 ORX95876.1 - 5.3 6.3 12.1 24 4.2 12.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Glyco_hydro_3_C PF01915.22 ORX95877.1 - 2e-50 171.6 0.1 3.3e-50 170.9 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 ORX95877.1 - 2.6e-33 115.8 0.0 4.7e-33 114.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 ORX95877.1 - 1.5e-20 73.1 0.0 2.9e-20 72.2 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain DNA_pol_B PF00136.21 ORX95879.1 - 6.4e-146 486.7 0.7 1e-145 486.0 0.7 1.4 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 ORX95879.1 - 3.3e-85 286.2 0.0 5e-85 285.6 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 ORX95879.1 - 8.9e-18 64.5 9.0 2.1e-17 63.4 9.0 1.7 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_exo2 PF10108.9 ORX95879.1 - 0.00073 19.3 0.0 0.0016 18.2 0.0 1.5 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB DNA_pol_B_2 PF03175.13 ORX95879.1 - 0.0014 17.6 1.0 0.076 11.9 0.0 2.5 2 0 0 2 2 2 2 DNA polymerase type B, organellar and viral RNase_H_2 PF13482.6 ORX95879.1 - 0.037 14.0 0.6 0.28 11.2 0.6 2.4 1 1 0 1 1 1 0 RNase_H superfamily C1_1 PF00130.22 ORX95879.1 - 0.5 10.3 9.9 0.23 11.4 1.0 2.6 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) HATPase_c_3 PF13589.6 ORX95880.1 - 0.0016 18.3 0.0 0.0037 17.1 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF3883 PF13020.6 ORX95880.1 - 0.1 12.7 0.0 0.26 11.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3883) KcnmB2_inactiv PF09303.10 ORX95880.1 - 0.19 11.6 0.5 0.43 10.4 0.5 1.6 1 0 0 1 1 1 0 KCNMB2, ball and chain domain Amidohydro_2 PF04909.14 ORX95881.1 - 5.1e-31 108.5 0.1 8e-31 107.9 0.1 1.3 1 1 0 1 1 1 1 Amidohydrolase TatD_DNase PF01026.21 ORX95881.1 - 0.00031 20.2 0.0 0.12 11.7 0.0 2.2 2 0 0 2 2 2 2 TatD related DNase DIOX_N PF14226.6 ORX95882.1 - 5.9e-26 91.5 0.0 9.4e-26 90.9 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 ORX95882.1 - 2.1e-17 63.4 0.0 3.3e-17 62.8 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily GAT PF03127.14 ORX95882.1 - 0.19 12.1 0.0 0.44 10.9 0.0 1.6 1 0 0 1 1 1 0 GAT domain Glyco_hydro_20 PF00728.22 ORX95883.1 - 8.6e-25 87.9 0.4 5.3e-22 78.7 0.4 2.8 2 1 0 2 2 2 1 Glycosyl hydrolase family 20, catalytic domain Glyco_hydro_20b PF02838.15 ORX95883.1 - 2.9e-09 37.8 0.0 6.4e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Fungal_trans PF04082.18 ORX95885.1 - 2.8e-15 56.1 4.7 4.5e-15 55.4 4.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORX95885.1 - 6.5e-07 29.4 12.7 1.3e-06 28.4 12.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DSBA PF01323.20 ORX95886.1 - 2.4e-54 184.1 0.0 9.4e-29 100.6 0.0 2.8 2 1 0 2 2 2 2 DSBA-like thioredoxin domain TetR_C_20 PF17925.1 ORX95886.1 - 0.35 11.2 3.7 13 6.1 0.5 2.9 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain Glyco_hydro_43 PF04616.14 ORX95887.1 - 2.8e-101 338.7 1.0 3.3e-101 338.4 0.4 1.4 2 0 0 2 2 2 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 ORX95887.1 - 2.1e-42 145.1 0.0 2.8e-42 144.7 0.0 1.2 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain Glyco_hydro_32N PF00251.20 ORX95887.1 - 0.01 15.4 0.1 0.024 14.2 0.2 1.5 1 1 0 1 1 1 0 Glycosyl hydrolases family 32 N-terminal domain GMC_oxred_N PF00732.19 ORX95916.1 - 7.9e-59 199.4 0.0 9.1e-59 199.2 0.0 1.0 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 ORX95916.1 - 0.016 14.3 0.4 0.025 13.6 0.4 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein DAO PF01266.24 ORX95916.1 - 0.3 10.6 2.7 1.2 8.6 2.7 2.0 1 1 0 1 1 1 0 FAD dependent oxidoreductase Transp_cyt_pur PF02133.15 ORX95917.1 - 6.4e-79 265.8 36.5 7.5e-79 265.5 36.5 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Aldedh PF00171.22 ORX95918.1 - 4.2e-153 510.2 0.4 5e-153 509.9 0.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 ORX95918.1 - 0.011 15.2 0.0 3 7.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) Amdase PF17645.1 ORX95919.1 - 1.2e-19 70.8 0.0 1.4e-19 70.6 0.0 1.1 1 0 0 1 1 1 1 Arylmalonate decarboxylase Asp_Glu_race PF01177.22 ORX95919.1 - 2.7e-06 27.4 0.0 3.5e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase Fungal_trans PF04082.18 ORX95920.1 - 1.7e-19 69.9 0.8 4.1e-19 68.6 0.8 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORX95920.1 - 0.0029 17.7 15.3 0.0055 16.8 15.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Amidohydro_2 PF04909.14 ORX95921.1 - 5.9e-22 78.8 0.0 7.3e-22 78.5 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase FAD_binding_3 PF01494.19 ORX95922.1 - 1.8e-10 40.6 0.6 3.9e-09 36.2 0.6 2.3 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 ORX95922.1 - 0.00017 20.9 2.0 0.0062 15.8 0.5 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORX95922.1 - 0.0032 17.6 0.2 0.0083 16.3 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 ORX95922.1 - 0.015 14.6 0.0 0.028 13.7 0.0 1.4 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 ORX95922.1 - 0.037 13.1 0.3 0.059 12.4 0.3 1.3 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.24 ORX95922.1 - 0.72 9.4 4.0 1.1 8.8 3.5 1.5 1 1 0 1 1 1 0 FAD dependent oxidoreductase zf-RING_2 PF13639.6 ORX95923.1 - 7e-12 45.5 4.0 9.2e-12 45.1 4.0 1.2 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 ORX95923.1 - 5.3e-09 35.7 1.9 9.9e-08 31.6 0.5 2.2 2 0 0 2 2 2 1 RING-like zinc finger zf-ANAPC11 PF12861.7 ORX95923.1 - 1.2e-08 34.9 0.7 1.6e-08 34.5 0.7 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 ORX95923.1 - 3.3e-08 33.7 6.6 1e-07 32.1 6.6 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 ORX95923.1 - 4.2e-08 32.9 3.3 6.3e-08 32.4 3.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORX95923.1 - 3.4e-07 30.2 2.8 1.6e-06 28.0 1.5 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 ORX95923.1 - 7.2e-07 29.0 4.6 1.4e-06 28.0 4.6 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.7 ORX95923.1 - 9.3e-07 28.9 3.3 1.3e-06 28.4 3.3 1.2 1 0 0 1 1 1 1 RING-variant domain Prok-RING_4 PF14447.6 ORX95923.1 - 3.1e-06 27.0 3.8 0.00011 22.0 0.8 2.2 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 ORX95923.1 - 1.3e-05 25.0 2.5 0.00047 20.1 0.4 2.1 2 0 0 2 2 2 1 zinc-RING finger domain Rad50_zn_hook PF04423.14 ORX95923.1 - 3.1e-05 23.7 1.1 0.00038 20.2 0.2 2.1 2 0 0 2 2 2 1 Rad50 zinc hook motif Zn_ribbon_17 PF17120.5 ORX95923.1 - 5.2e-05 22.8 5.8 0.00011 21.8 5.8 1.7 1 1 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 ORX95923.1 - 0.00014 21.6 3.9 0.00047 20.0 3.8 1.7 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 ORX95923.1 - 0.00016 21.4 3.4 0.00032 20.4 3.4 1.5 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 ORX95923.1 - 0.00022 21.3 5.3 0.0023 18.0 5.3 2.0 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_1 PF14446.6 ORX95923.1 - 0.00057 19.8 4.5 0.15 12.0 1.2 2.1 2 0 0 2 2 2 2 Prokaryotic RING finger family 1 Zf_RING PF16744.5 ORX95923.1 - 0.001 19.1 2.5 0.0046 17.1 0.2 2.0 1 1 1 2 2 2 1 KIAA1045 RING finger zf-Nse PF11789.8 ORX95923.1 - 0.002 17.9 2.0 0.004 16.9 2.0 1.5 1 1 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit PHD PF00628.29 ORX95923.1 - 0.0033 17.3 4.2 0.005 16.7 4.2 1.3 1 0 0 1 1 1 1 PHD-finger zf-RING-like PF08746.11 ORX95923.1 - 0.0089 16.3 2.0 0.0089 16.3 2.0 1.9 2 0 0 2 2 2 1 RING-like domain YdjO PF14169.6 ORX95923.1 - 0.0097 15.6 0.4 0.18 11.6 0.0 2.2 2 0 0 2 2 2 1 Cold-inducible protein YdjO FANCL_C PF11793.8 ORX95923.1 - 0.025 14.8 7.6 0.31 11.2 7.6 2.5 1 1 0 1 1 1 0 FANCL C-terminal domain zinc_ribbon_9 PF14369.6 ORX95923.1 - 0.037 14.3 3.7 3.1 8.2 0.2 2.2 2 0 0 2 2 2 0 zinc-ribbon Rubredoxin PF00301.20 ORX95923.1 - 0.051 13.6 2.0 1.7 8.7 0.2 2.4 2 0 0 2 2 2 0 Rubredoxin Zn-ribbon_8 PF09723.10 ORX95923.1 - 0.072 13.2 4.0 1.3 9.2 0.8 2.3 2 0 0 2 2 2 0 Zinc ribbon domain zf-Di19 PF05605.12 ORX95923.1 - 0.14 12.5 4.9 24 5.3 4.9 2.2 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_9 PF16293.5 ORX95923.1 - 0.23 11.3 2.5 0.69 9.8 0.0 2.3 2 1 0 2 2 2 0 C2H2 type zinc-finger (1 copy) GAGA PF09237.11 ORX95923.1 - 0.53 10.1 6.7 4.2 7.2 1.7 2.3 1 1 1 2 2 2 0 GAGA factor C1_1 PF00130.22 ORX95923.1 - 0.58 10.1 4.7 6.8 6.7 0.1 2.4 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-MIZ PF02891.20 ORX95923.1 - 3 7.6 7.4 23 4.8 4.5 2.6 2 1 0 2 2 2 0 MIZ/SP-RING zinc finger SUR7 PF06687.12 ORX95924.1 - 7.9e-12 45.3 9.8 9.7e-12 45.0 9.8 1.1 1 0 0 1 1 1 1 SUR7/PalI family Amelogenin PF02948.15 ORX95924.1 - 0.16 12.6 0.1 0.28 11.8 0.1 1.3 1 0 0 1 1 1 0 Amelogenin ArAE_1 PF06081.11 ORX95924.1 - 3.3 7.9 17.1 24 5.1 4.2 2.3 1 1 1 2 2 2 0 Aromatic acid exporter family member 1 Clostridium_P47 PF06597.11 ORX95924.1 - 9.9 4.8 7.8 8.8 4.9 0.5 2.1 1 1 1 2 2 2 0 Clostridium P-47 protein Glyco_hydro_35 PF01301.19 ORX95925.1 - 4.4e-88 295.9 0.0 5.5e-88 295.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.15 ORX95925.1 - 2.6e-05 23.7 0.4 0.00019 20.9 0.4 2.1 1 1 0 1 1 1 1 Beta-galactosidase BetaGal_dom4_5 PF13364.6 ORX95925.1 - 4.3e-05 24.1 0.0 0.00016 22.2 0.0 2.0 1 0 0 1 1 1 1 Beta-galactosidase jelly roll domain Glyco_hydro_20 PF00728.22 ORX95926.1 - 4.1e-26 92.2 1.7 1.4e-23 83.9 0.1 2.4 1 1 1 2 2 2 2 Glycosyl hydrolase family 20, catalytic domain Glyco_hydro_20b PF02838.15 ORX95926.1 - 1.7e-08 35.3 0.0 3.6e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 DUF1996 PF09362.10 ORX95927.1 - 9.8e-77 258.1 0.5 1.2e-76 257.8 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) PQ-loop PF04193.14 ORX95928.1 - 1.3e-06 28.0 1.9 1.3e-06 28.0 1.9 2.5 2 1 0 2 2 2 1 PQ loop repeat DUF4386 PF14329.6 ORX95928.1 - 0.037 13.9 1.0 0.071 13.0 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4386) Chlorophyllase2 PF12740.7 ORX95929.1 - 1.7e-06 27.1 0.0 2.4e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 ORX95929.1 - 0.00011 21.3 0.0 0.00016 20.8 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase PAF-AH_p_II PF03403.13 ORX95929.1 - 0.00012 20.8 0.1 0.0039 15.8 0.0 2.1 1 1 1 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II AA_permease PF00324.21 ORX95930.1 - 1.5e-143 478.9 36.9 1.9e-143 478.6 36.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ORX95930.1 - 6.1e-36 124.2 42.4 7.9e-36 123.8 42.4 1.2 1 0 0 1 1 1 1 Amino acid permease Peptidase_C48 PF02902.19 ORX95932.1 - 0.0026 17.6 0.0 0.0084 16.0 0.0 1.8 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Sugar_tr PF00083.24 ORX95935.1 - 1.2e-83 281.6 21.2 1.3e-83 281.3 21.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORX95935.1 - 8.9e-41 140.0 51.3 2.9e-32 112.0 27.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 ORX95935.1 - 0.00015 20.2 9.8 0.0045 15.3 1.0 2.7 2 1 1 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family TRI12 PF06609.13 ORX95935.1 - 0.00024 19.7 1.2 0.00024 19.7 1.2 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF3792 PF12670.7 ORX95935.1 - 0.017 15.3 4.1 0.017 15.3 4.1 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF3792) DUF1673 PF07895.11 ORX95935.1 - 0.06 13.0 3.4 0.17 11.6 3.2 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1673) Glyco_hydro_2_C PF02836.17 ORX95936.1 - 6.3e-100 334.2 0.1 9.1e-100 333.7 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.17 ORX95936.1 - 5.8e-70 235.7 0.0 9.7e-70 234.9 0.0 1.4 1 0 0 1 1 1 1 Beta galactosidase small chain Glyco_hydro_2_N PF02837.18 ORX95936.1 - 7.1e-41 139.9 0.3 2.5e-40 138.2 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain DUF4981 PF16353.5 ORX95936.1 - 1e-20 74.0 0.0 6.1e-19 68.3 0.0 2.9 3 0 0 3 3 3 1 Domain of unknown function(DUF4981) Glyco_hydro_2 PF00703.21 ORX95936.1 - 9.9e-14 51.9 0.0 3.1e-13 50.4 0.0 1.9 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.6 ORX95936.1 - 0.015 15.9 0.0 0.049 14.2 0.0 1.9 1 0 0 1 1 1 0 Beta-galactosidase jelly roll domain CN_hydrolase PF00795.22 ORX95960.1 - 4.3e-40 137.7 0.0 5.3e-40 137.4 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.17 ORX95960.1 - 0.018 14.2 0.0 0.03 13.5 0.0 1.2 1 0 0 1 1 1 0 NAD synthase HATPase_c PF02518.26 ORX95962.1 - 1.3e-22 80.4 0.0 2.7e-22 79.4 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 ORX95962.1 - 3.8e-20 72.1 0.5 2.8e-19 69.3 0.4 2.5 3 0 0 3 3 3 1 Response regulator receiver domain HisKA PF00512.25 ORX95962.1 - 1.8e-13 50.3 0.0 3.7e-13 49.3 0.0 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 ORX95962.1 - 0.0074 16.1 0.0 0.019 14.8 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase NPCC PF08058.11 ORX95963.1 - 1.5 8.9 4.2 2.5 8.1 0.6 2.6 2 1 0 2 2 2 0 Nuclear pore complex component Reticulon PF02453.17 ORX95964.1 - 4.2e-32 111.3 4.8 7.1e-32 110.5 4.8 1.4 1 0 0 1 1 1 1 Reticulon Apolipoprotein PF01442.18 ORX95964.1 - 0.01 15.7 1.5 0.28 11.0 0.1 2.1 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain WXG100 PF06013.12 ORX95964.1 - 3.5 7.9 6.8 0.85 9.9 0.7 2.5 2 1 0 2 2 2 0 Proteins of 100 residues with WXG Cupin_8 PF13621.6 ORX95966.1 - 3.8e-34 118.5 0.0 5.8e-34 117.9 0.0 1.3 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 ORX95966.1 - 6.6e-08 32.4 0.0 4.2e-06 26.5 0.0 2.3 2 0 0 2 2 2 2 Cupin superfamily protein JmjC PF02373.22 ORX95966.1 - 0.033 14.6 0.0 0.079 13.4 0.0 1.6 2 0 0 2 2 2 0 JmjC domain, hydroxylase Cupin_2 PF07883.11 ORX95966.1 - 0.12 12.1 0.0 0.6 9.9 0.0 2.0 2 0 0 2 2 2 0 Cupin domain Aminotran_1_2 PF00155.21 ORX95967.1 - 5.2e-63 213.4 0.0 5.9e-63 213.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 ORX95967.1 - 0.0017 17.3 0.0 0.0024 16.7 0.0 1.1 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase Alliinase_C PF04864.13 ORX95967.1 - 0.15 10.9 0.0 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 Allinase Esterase_phd PF10503.9 ORX95968.1 - 1.8e-17 63.6 0.8 4.6e-17 62.3 0.8 1.6 1 1 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 ORX95968.1 - 9.3e-11 41.6 0.3 1.5e-10 40.9 0.3 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 ORX95968.1 - 0.00055 19.7 0.4 0.004 16.8 0.1 2.0 1 1 1 2 2 2 1 alpha/beta hydrolase fold Esterase PF00756.20 ORX95968.1 - 0.00058 19.6 0.3 0.00085 19.0 0.3 1.3 1 1 0 1 1 1 1 Putative esterase COesterase PF00135.28 ORX95968.1 - 0.043 12.7 0.1 0.073 11.9 0.1 1.3 1 0 0 1 1 1 0 Carboxylesterase family DUF782 PF05614.11 ORX95969.1 - 0.13 12.6 0.0 0.31 11.5 0.0 1.6 1 0 0 1 1 1 0 Circovirus protein of unknown function (DUF782) RimM PF01782.18 ORX95969.1 - 0.15 12.3 0.0 0.59 10.4 0.0 2.0 2 0 0 2 2 2 0 RimM N-terminal domain Acetyltransf_18 PF18014.1 ORX95970.1 - 3.5e-10 39.8 0.0 1.2e-09 38.0 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORX95970.1 - 6.8e-07 29.5 0.0 6.6e-06 26.3 0.0 2.4 2 1 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ORX95970.1 - 7.7e-06 25.9 0.0 2.8e-05 24.0 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ORX95970.1 - 7e-05 23.2 0.0 0.0002 21.7 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 ORX95970.1 - 0.059 13.4 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Isochorismatase PF00857.20 ORX95971.1 - 2e-21 77.0 0.0 5.2e-21 75.6 0.0 1.6 1 1 0 1 1 1 1 Isochorismatase family ATP_bind_3 PF01171.20 ORX95972.1 - 1.7e-17 63.8 0.0 2.6e-17 63.2 0.0 1.3 1 0 0 1 1 1 1 PP-loop family zn-ribbon_14 PF16503.5 ORX95972.1 - 2.6e-16 58.8 3.5 2.6e-16 58.8 3.5 3.0 3 0 0 3 3 3 1 Zinc-ribbon RecR PF02132.15 ORX95972.1 - 0.009 15.6 0.7 0.009 15.6 0.7 3.0 3 0 0 3 3 3 1 RecR protein tRNA_Me_trans PF03054.16 ORX95972.1 - 0.046 12.5 0.0 0.078 11.8 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase zf-UBR PF02207.20 ORX95972.1 - 0.21 11.8 4.4 4.7 7.5 0.6 2.5 2 0 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) Glyco_hydro_31 PF01055.26 ORX95973.1 - 3.2e-153 511.1 9.7 5e-153 510.4 9.7 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 ORX95973.1 - 7.5e-35 119.6 0.3 1.9e-34 118.3 0.3 1.7 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 ORX95973.1 - 5.3e-12 45.9 0.5 5.3e-12 45.9 0.5 2.2 2 0 0 2 2 2 1 Galactose mutarotase-like Acid_PPase PF12689.7 ORX95974.1 - 1.4e-63 213.7 0.0 1.7e-63 213.5 0.0 1.1 1 0 0 1 1 1 1 Acid Phosphatase ATG22 PF11700.8 ORX95975.1 - 5.1e-08 32.0 0.3 5.3e-08 31.9 0.3 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like Ank_2 PF12796.7 ORX95977.1 - 2.9e-18 66.2 0.0 0.00062 20.3 0.0 5.3 4 1 0 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ORX95977.1 - 3.6e-16 57.6 0.2 0.059 13.9 0.0 8.8 10 0 0 10 10 10 4 Ankyrin repeat Ank_4 PF13637.6 ORX95977.1 - 1.1e-15 57.8 0.2 0.023 15.3 0.0 6.6 5 1 1 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 ORX95977.1 - 7.9e-13 48.4 0.1 0.0028 17.9 0.0 6.5 5 2 1 6 6 6 3 Ankyrin repeats (many copies) Ank PF00023.30 ORX95977.1 - 0.00055 20.3 3.7 3.4 8.3 0.1 5.8 6 1 0 6 6 6 2 Ankyrin repeat Peptidase_S28 PF05577.12 ORX95978.1 - 6.5e-43 147.1 0.2 6e-42 143.9 0.2 2.1 1 1 0 1 1 1 1 Serine carboxypeptidase S28 zf-trcl PF13451.6 ORX95979.1 - 0.16 11.9 1.4 0.21 11.5 0.4 1.7 2 0 0 2 2 2 0 Probable zinc-ribbon domain ENTH PF01417.20 ORX95980.1 - 2.8e-46 156.6 0.0 4.6e-46 155.9 0.0 1.3 1 0 0 1 1 1 1 ENTH domain DUF4264 PF14084.6 ORX95980.1 - 0.0011 18.6 0.1 0.0022 17.6 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4264) UIM PF02809.20 ORX95980.1 - 0.0026 17.5 9.7 0.0064 16.3 1.0 2.7 2 0 0 2 2 2 2 Ubiquitin interaction motif ANTH PF07651.16 ORX95980.1 - 0.0049 15.9 0.0 0.0089 15.0 0.0 1.4 1 0 0 1 1 1 1 ANTH domain Rax2 PF12768.7 ORX96019.1 - 0.00069 19.1 0.0 0.00093 18.7 0.0 1.2 1 0 0 1 1 1 1 Cortical protein marker for cell polarity VSP PF03302.13 ORX96019.1 - 0.014 14.3 0.2 0.019 13.8 0.2 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein EphA2_TM PF14575.6 ORX96019.1 - 0.031 15.2 0.0 0.058 14.3 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DAP10 PF07213.11 ORX96019.1 - 0.037 14.0 0.0 0.064 13.2 0.0 1.3 1 0 0 1 1 1 0 DAP10 membrane protein DUF4381 PF14316.6 ORX96019.1 - 0.099 12.9 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Peptidase_A22B PF04258.13 ORX96020.1 - 1.5e-60 205.2 3.2 3.2e-59 200.8 3.2 2.5 1 1 0 1 1 1 1 Signal peptide peptidase FAM176 PF14851.6 ORX96020.1 - 0.0013 18.4 0.7 0.79 9.4 0.2 2.5 2 0 0 2 2 2 2 FAM176 family SPP PF06550.11 ORX96020.1 - 0.0017 17.9 5.9 0.0017 17.9 5.9 2.6 2 1 0 2 2 2 1 Signal-peptide peptidase, presenilin aspartyl protease GOLD_2 PF13897.6 ORX96020.1 - 0.041 14.4 1.9 1.5 9.4 1.0 2.7 3 0 0 3 3 3 0 Golgi-dynamics membrane-trafficking CPSF100_C PF13299.6 ORX96020.1 - 0.084 13.1 0.1 7.6 6.7 0.1 2.2 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal CrgA PF06781.12 ORX96020.1 - 0.11 12.6 0.0 0.68 10.0 0.0 2.4 2 0 0 2 2 2 0 Cell division protein CrgA RCC1 PF00415.18 ORX96023.1 - 1.8e-12 47.7 4.5 0.0023 18.5 0.2 5.1 4 1 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 ORX96023.1 - 5.9e-05 22.8 0.7 0.14 12.0 0.0 3.1 3 0 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat Arf PF00025.21 ORX96026.1 - 1.2e-49 168.2 0.0 1.3e-49 168.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 ORX96026.1 - 7e-09 35.3 0.0 1.2e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 G-protein alpha subunit Roc PF08477.13 ORX96026.1 - 0.00055 20.1 0.0 0.00072 19.8 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 ORX96026.1 - 0.0056 16.3 0.0 0.0068 16.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 ORX96026.1 - 0.015 14.6 0.0 0.016 14.6 0.0 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 ORX96026.1 - 0.076 13.1 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 50S ribosome-binding GTPase Nup35_RRM PF05172.13 ORX96027.1 - 0.01 15.8 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Ribosomal_L14e PF01929.17 ORX96029.1 - 5.6e-30 103.6 1.1 8.3e-30 103.1 1.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.29 ORX96029.1 - 4.5e-06 26.4 0.0 1e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 KOW motif NAC PF01849.18 ORX96030.1 - 2.5e-23 81.8 0.1 1.1e-22 79.8 0.0 2.0 2 0 0 2 2 2 1 NAC domain SelP_N PF04592.14 ORX96030.1 - 0.026 13.9 7.1 0.048 13.1 7.0 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region UreE_C PF05194.12 ORX96030.1 - 0.076 13.5 7.3 0.21 12.1 7.3 1.7 1 0 0 1 1 1 0 UreE urease accessory protein, C-terminal domain Cytomega_UL84 PF06284.11 ORX96030.1 - 0.3 9.5 2.1 0.4 9.1 2.1 1.2 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein PGA2 PF07543.12 ORX96030.1 - 1.7 8.7 11.8 1.2 9.1 7.3 2.1 2 0 0 2 2 2 0 Protein trafficking PGA2 DUF3824 PF12868.7 ORX96030.1 - 2.4 8.8 9.0 0.58 10.8 3.8 2.2 2 0 0 2 2 2 0 Domain of unknwon function (DUF3824) Myc_N PF01056.18 ORX96030.1 - 3.3 7.5 14.0 1.2 8.9 10.1 1.8 1 1 1 2 2 2 0 Myc amino-terminal region Pep1_7 PF17232.2 ORX96030.1 - 3.5 8.1 9.5 0.27 11.7 1.1 2.4 2 0 0 2 2 2 0 Elicitor peptide 1-7 DUF4578 PF15147.6 ORX96030.1 - 6.7 7.6 6.2 5.2 8.0 4.7 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4578) Mt_ATP-synt_D PF05873.12 ORX96031.1 - 7.6e-24 84.3 0.8 9.5e-24 84.0 0.8 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) TPR_MLP1_2 PF07926.12 ORX96031.1 - 0.01 15.9 2.3 1.8 8.6 0.0 2.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Dor1 PF04124.12 ORX96031.1 - 0.072 11.8 0.7 0.088 11.5 0.7 1.2 1 0 0 1 1 1 0 Dor1-like family Laminin_II PF06009.12 ORX96031.1 - 0.25 11.3 3.9 17 5.4 0.9 2.9 1 1 2 3 3 3 0 Laminin Domain II Ank PF00023.30 ORX96032.1 - 2e-07 31.2 0.8 0.025 15.0 0.0 2.8 2 1 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 ORX96032.1 - 3e-07 30.6 0.1 4.4e-05 23.7 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 ORX96032.1 - 1.8e-05 25.2 0.1 4.4e-05 24.0 0.1 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORX96032.1 - 3.7e-05 24.2 0.2 0.00077 20.0 0.0 2.4 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORX96032.1 - 0.00042 20.5 0.0 0.053 14.1 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat POP1 PF06978.11 ORX96033.1 - 7.5e-59 199.2 10.2 7.5e-59 199.2 10.2 1.8 2 0 0 2 2 2 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.12 ORX96033.1 - 1.5e-30 105.3 0.8 1.5e-30 105.3 0.8 2.6 3 0 0 3 3 3 1 POPLD (NUC188) domain Coiled PF05710.12 ORX96034.1 - 0.39 11.6 8.4 0.32 11.8 7.3 1.5 1 1 1 2 2 2 0 Coiled coil PIR PF00399.19 ORX96035.1 - 3.3e-15 55.2 41.0 0.0009 18.7 0.7 7.2 7 0 0 7 7 7 6 Yeast PIR protein repeat Collagen PF01391.18 ORX96037.1 - 0.00049 19.8 1.5 0.00069 19.3 1.5 1.3 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Phage_BR0599 PF09356.10 ORX96037.1 - 0.1 12.9 8.2 56 4.2 0.0 4.6 1 1 4 5 5 5 0 Phage conserved hypothetical protein BR0599 4PPT_N PF17837.1 ORX96060.1 - 0.13 12.3 0.0 0.34 11.0 0.0 1.6 1 0 0 1 1 1 0 4'-phosphopantetheinyl transferase N-terminal domain CHCH PF06747.13 ORX96061.1 - 3.2e-05 23.9 2.4 3.2e-05 23.9 2.4 2.2 2 1 1 3 3 3 1 CHCH domain MTCP1 PF08991.10 ORX96061.1 - 0.0008 19.6 0.4 0.0037 17.5 0.2 1.9 2 0 0 2 2 2 1 Mature-T-Cell Proliferation I type COX17 PF05051.13 ORX96061.1 - 0.083 13.3 0.9 0.25 11.7 1.0 1.8 2 0 0 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) GCK PF07802.11 ORX96061.1 - 0.11 12.9 1.2 1.1 9.8 0.1 2.1 1 1 1 2 2 2 0 GCK domain Sod_Fe_C PF02777.18 ORX96062.1 - 1.6e-16 60.3 0.4 2.3e-08 34.1 0.5 2.6 2 1 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain TctB PF07331.11 ORX96063.1 - 0.11 12.8 0.0 0.18 12.1 0.0 1.3 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family DUF5346 PF17281.2 ORX96063.1 - 2.8 8.0 10.8 0.42 10.6 5.3 2.4 1 1 1 2 2 2 0 Family of unknown function (DUF5346) Granulin PF00396.18 ORX96063.1 - 5.6 7.4 27.9 4.5 7.7 8.2 3.4 3 0 0 3 3 3 0 Granulin Zn-C2H2_12 PF18112.1 ORX96064.1 - 0.1 13.1 0.3 0.22 12.0 0.3 1.6 1 0 0 1 1 1 0 Autophagy receptor zinc finger-C2H2 domain zf-RING_UBOX PF13445.6 ORX96064.1 - 0.76 9.8 4.2 6 7.0 4.2 2.3 1 1 0 1 1 1 0 RING-type zinc-finger zf-RING_2 PF13639.6 ORX96065.1 - 0.015 15.6 1.1 0.019 15.3 0.1 1.7 2 0 0 2 2 2 0 Ring finger domain zf-rbx1 PF12678.7 ORX96065.1 - 0.054 13.8 0.5 0.12 12.7 0.0 1.8 2 0 0 2 2 2 0 RING-H2 zinc finger domain Zn_ribbon_17 PF17120.5 ORX96065.1 - 0.17 11.6 0.1 0.32 10.7 0.1 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 ORX96065.1 - 0.21 11.5 0.5 0.86 9.5 0.1 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Glyco_hydro_79C PF16862.5 ORX96066.1 - 5.1e-17 62.6 1.0 5.1e-17 62.6 1.0 2.8 4 0 0 4 4 4 1 Glycosyl hydrolase family 79 C-terminal beta domain DUF1748 PF08520.10 ORX96066.1 - 0.0054 16.6 0.0 0.052 13.5 0.0 2.4 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF1748) DSBA PF01323.20 ORX96067.1 - 5.3e-22 78.5 0.0 6e-22 78.4 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain UCH PF00443.29 ORX96068.1 - 1.8e-24 86.6 0.0 3.3e-24 85.8 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 ORX96068.1 - 2.2e-10 40.7 0.1 4.2e-10 39.8 0.1 1.4 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 ORX96068.1 - 0.026 14.1 0.1 0.38 10.3 0.1 2.2 1 1 1 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase Cpn60_TCP1 PF00118.24 ORX96069.1 - 3.1e-143 478.0 13.3 3.6e-143 477.8 13.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family CRM1_repeat PF18777.1 ORX96069.1 - 0.1 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Chromosome region maintenance or exportin repeat Ribonuc_2-5A PF06479.12 ORX96070.1 - 2.3e-43 147.4 0.1 3.7e-43 146.7 0.1 1.3 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase PF00069.25 ORX96070.1 - 1.5e-42 145.8 0.0 5e-42 144.1 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX96070.1 - 1.4e-18 67.2 0.0 2.7e-18 66.2 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORX96070.1 - 0.00049 19.0 0.0 0.00088 18.2 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase PQQ_2 PF13360.6 ORX96070.1 - 0.0059 16.2 0.1 0.16 11.5 0.0 2.4 1 1 1 2 2 2 1 PQQ-like domain PQQ PF01011.21 ORX96070.1 - 0.015 15.2 0.0 1.3 9.1 0.0 2.7 2 0 0 2 2 2 0 PQQ enzyme repeat APH PF01636.23 ORX96070.1 - 0.038 13.9 0.1 0.57 10.1 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 ORX96070.1 - 0.12 11.7 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CcmD PF04995.14 ORX96071.1 - 0.012 15.7 3.6 0.063 13.4 1.5 2.4 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) OpgC_C PF10129.9 ORX96071.1 - 0.79 8.5 6.5 0.14 11.0 0.3 2.3 2 1 1 3 3 3 0 OpgC protein PLD_C PF12357.8 ORX96072.1 - 0.035 14.0 0.0 0.12 12.3 0.0 1.8 2 0 0 2 2 2 0 Phospholipase D C terminal DUF973 PF06157.11 ORX96072.1 - 0.14 11.2 0.0 0.19 10.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF973) Granulin PF00396.18 ORX96072.1 - 2.9 8.3 11.9 1.1 9.6 0.7 3.3 3 0 0 3 3 3 0 Granulin Methyltransf_12 PF08242.12 ORX96073.1 - 2.7e-14 53.7 0.0 6.9e-14 52.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORX96073.1 - 1.8e-12 47.8 0.0 4.5e-12 46.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORX96073.1 - 1.5e-10 41.1 0.0 2.7e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORX96073.1 - 3.1e-09 37.4 0.0 9.7e-09 35.8 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORX96073.1 - 3.1e-06 27.1 0.0 6.2e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORX96073.1 - 7.2e-06 25.5 0.0 1.2e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_24 PF13578.6 ORX96073.1 - 0.002 19.1 0.0 0.0041 18.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ORX96073.1 - 0.012 15.2 0.0 0.022 14.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Polyketide_cyc PF03364.20 ORX96074.1 - 1.2e-21 77.2 0.0 1.9e-21 76.6 0.0 1.3 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 ORX96074.1 - 0.00023 21.5 0.1 0.0016 18.7 0.1 2.0 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport G_glu_transpept PF01019.21 ORX96075.1 - 3.4e-157 524.3 0.0 3.9e-157 524.1 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase TPR_14 PF13428.6 ORX96077.1 - 3.3e-10 39.9 0.5 0.31 12.0 0.0 5.9 3 1 2 5 5 5 3 Tetratricopeptide repeat Suf PF05843.14 ORX96077.1 - 7.1e-06 26.2 3.6 0.0019 18.2 0.0 3.0 3 0 0 3 3 3 2 Suppressor of forked protein (Suf) NRDE-2 PF08424.10 ORX96077.1 - 0.0019 17.4 1.6 6.8 5.7 0.4 3.9 3 1 0 3 3 3 2 NRDE-2, necessary for RNA interference TPR_12 PF13424.6 ORX96077.1 - 0.012 15.9 0.3 0.093 13.0 0.0 2.7 4 0 0 4 4 4 0 Tetratricopeptide repeat IMCp PF12314.8 ORX96077.1 - 0.028 14.7 0.4 0.057 13.7 0.4 1.4 1 0 0 1 1 1 0 Inner membrane complex protein TPR_19 PF14559.6 ORX96077.1 - 0.091 13.3 0.9 3.7 8.1 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat HAT PF02184.16 ORX96077.1 - 0.12 12.4 18.3 12 5.9 0.1 6.6 7 1 0 7 7 7 0 HAT (Half-A-TPR) repeat Fungal_trans_2 PF11951.8 ORX96079.1 - 3.6e-94 315.7 0.1 5e-94 315.3 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORX96079.1 - 3.6e-06 27.0 9.4 6.6e-06 26.2 9.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.32 ORX96120.1 - 1.4e-42 142.9 27.1 1.6e-10 41.4 0.6 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat NACHT PF05729.12 ORX96120.1 - 3.9e-23 82.2 0.1 7.7e-23 81.2 0.1 1.5 1 0 0 1 1 1 1 NACHT domain ANAPC4_WD40 PF12894.7 ORX96120.1 - 2.3e-16 59.8 3.0 0.0069 16.7 0.0 5.0 1 1 3 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 ORX96120.1 - 7.7e-14 51.4 7.1 3.6e-06 26.2 0.5 3.5 1 1 1 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 ORX96120.1 - 5.1e-13 48.5 5.5 0.024 13.3 0.2 4.4 3 1 1 4 4 4 4 Nucleoporin Nup120/160 Nbas_N PF15492.6 ORX96120.1 - 8.5e-06 25.3 7.7 1.2 8.4 0.1 4.2 1 1 3 4 4 4 4 Neuroblastoma-amplified sequence, N terminal DUF5114 PF17141.4 ORX96120.1 - 0.0014 19.1 0.0 7.2 7.2 0.0 3.7 1 1 3 4 4 4 1 Domain of unknown function (DUF5114) AAA_19 PF13245.6 ORX96120.1 - 0.035 14.4 1.0 0.63 10.4 1.0 2.3 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.9 ORX96120.1 - 0.045 13.0 1.1 0.4 9.9 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) WD40_like PF17005.5 ORX96120.1 - 0.047 13.0 0.0 4 6.7 0.0 3.2 2 1 2 4 4 4 0 WD40-like domain DAP3 PF10236.9 ORX96120.1 - 0.047 12.9 0.7 1.1 8.3 0.7 2.2 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 AAA PF00004.29 ORX96120.1 - 0.15 12.5 0.1 0.93 9.9 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) HET PF06985.11 ORX96120.1 - 0.77 10.1 6.0 0.13 12.6 1.0 2.4 2 0 0 2 2 2 0 Heterokaryon incompatibility protein (HET) Pkinase PF00069.25 ORX96122.1 - 3.7e-11 42.9 0.0 1.4e-10 41.0 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX96122.1 - 1.3e-05 24.7 0.0 0.0045 16.3 0.0 2.6 2 1 0 2 2 2 2 Protein tyrosine kinase DDE_1 PF03184.19 ORX96123.1 - 0.029 14.0 0.0 0.074 12.7 0.0 1.7 1 0 0 1 1 1 0 DDE superfamily endonuclease DUF3328 PF11807.8 ORX96154.1 - 4.2e-46 157.5 0.0 5.5e-46 157.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DnaJ PF00226.31 ORX96155.1 - 1.4e-15 57.1 1.9 9.4e-15 54.5 0.4 2.5 2 0 0 2 2 2 1 DnaJ domain EHN PF06441.12 ORX96155.1 - 1.7 9.1 5.9 2.1 8.7 0.7 2.7 3 0 0 3 3 3 0 Epoxide hydrolase N terminus bZIP_2 PF07716.15 ORX96156.1 - 2.5e-06 27.5 17.5 1.4e-05 25.1 16.0 2.1 1 1 1 2 2 2 2 Basic region leucine zipper bZIP_1 PF00170.21 ORX96156.1 - 0.01 15.9 16.7 0.021 14.9 16.7 1.5 1 1 0 1 1 1 0 bZIP transcription factor Fib_alpha PF08702.10 ORX96156.1 - 0.67 10.1 6.4 0.94 9.7 6.4 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family CFEM PF05730.11 ORX96157.1 - 1.8e-11 43.9 9.7 2.2e-11 43.7 9.7 1.1 1 0 0 1 1 1 1 CFEM domain Antimicrobial25 PF16839.5 ORX96157.1 - 0.2 11.8 10.8 1.1 9.3 10.7 2.1 1 1 0 1 1 1 0 Nematode antimicrobial peptide Ank_2 PF12796.7 ORX96159.1 - 2.7e-15 56.7 0.0 1.7e-07 31.7 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORX96159.1 - 2.8e-12 46.9 0.0 0.00026 21.5 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORX96159.1 - 5.4e-12 44.8 0.5 0.0025 18.2 0.0 4.6 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 ORX96159.1 - 1.4e-06 28.4 0.7 0.15 12.6 0.1 3.6 2 1 1 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 ORX96159.1 - 2.7e-06 27.6 0.3 0.026 14.8 0.0 3.3 2 1 1 3 3 3 3 Ankyrin repeats (many copies) MFS_1 PF07690.16 ORX96160.1 - 9.3e-20 70.8 39.0 1.5e-19 70.2 39.0 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily adh_short PF00106.25 ORX96161.1 - 7.5e-32 110.4 0.7 2.1e-31 108.9 0.7 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORX96161.1 - 6.6e-22 78.2 0.0 7.5e-21 74.7 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 ORX96161.1 - 0.0075 15.7 0.1 3.9 6.8 0.1 2.7 1 1 1 2 2 2 2 Fungal family of unknown function (DUF1776) ADH_zinc_N PF00107.26 ORX96161.1 - 0.015 15.3 0.1 0.076 13.0 0.0 2.0 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Pyridoxal_deC PF00282.19 ORX96162.1 - 5.6e-05 22.0 0.1 9.7e-05 21.2 0.1 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain ImcF-related_N PF14331.6 ORX96162.1 - 0.18 11.1 0.0 0.27 10.5 0.0 1.2 1 0 0 1 1 1 0 ImcF-related N-terminal domain MFS_1 PF07690.16 ORX96165.1 - 3.5e-21 75.5 58.4 1.8e-15 56.8 38.5 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Zn_clus PF00172.18 ORX96166.1 - 5e-07 29.7 12.6 9.6e-07 28.8 12.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2039 PF10217.9 ORX96166.1 - 1.6 9.1 7.3 4 7.9 7.3 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) CAMSAP_CC1 PF17095.5 ORX96168.1 - 0.62 9.9 12.8 1.2 9.0 12.8 1.4 1 0 0 1 1 1 0 Spectrin-binding region of Ca2+-Calmodulin p450 PF00067.22 ORX96169.1 - 2.9e-50 171.4 0.0 3.9e-50 170.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MR_MLE_C PF13378.6 ORX96169.1 - 0.07 12.7 0.0 0.19 11.3 0.0 1.7 2 0 0 2 2 2 0 Enolase C-terminal domain-like AtuA PF07287.11 ORX96172.1 - 7.8e-125 416.2 0.0 9.3e-125 416.0 0.0 1.1 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA SPX PF03105.19 ORX96222.1 - 1e-84 285.7 4.5 2.5e-84 284.4 4.5 1.7 1 0 0 1 1 1 1 SPX domain EXS PF03124.14 ORX96222.1 - 1.1e-79 268.1 32.8 1.8e-59 201.8 13.3 2.1 1 1 1 2 2 2 2 EXS family Ribosom_S30AE_C PF16321.5 ORX96222.1 - 0.17 11.6 0.2 0.4 10.4 0.2 1.6 1 0 0 1 1 1 0 Sigma 54 modulation/S30EA ribosomal protein C terminus DUF3759 PF12585.8 ORX96223.1 - 1.2e-39 134.2 7.2 1.2e-39 134.2 7.2 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3759) DUF3824 PF12868.7 ORX96223.1 - 6.5 7.4 9.6 3.4 8.3 5.4 2.3 1 1 1 2 2 2 0 Domain of unknwon function (DUF3824) Abhydrolase_2 PF02230.16 ORX96224.1 - 5.6e-23 81.9 0.0 7.6e-23 81.5 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 ORX96224.1 - 0.00041 21.0 0.0 0.00051 20.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ORX96224.1 - 0.0005 19.8 0.1 0.0027 17.4 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.18 ORX96224.1 - 0.0036 16.9 0.0 0.005 16.4 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 ORX96224.1 - 0.015 14.6 0.0 1.7 7.8 0.1 2.3 2 1 0 2 2 2 0 Serine aminopeptidase, S33 PE-PPE PF08237.11 ORX96224.1 - 0.16 11.5 0.0 0.53 9.8 0.0 1.8 2 0 0 2 2 2 0 PE-PPE domain DHHA2 PF02833.14 ORX96225.1 - 2.7e-39 134.6 1.5 6.3e-39 133.4 0.4 1.9 2 0 0 2 2 2 1 DHHA2 domain DHH PF01368.20 ORX96225.1 - 0.00084 19.5 0.1 0.0051 17.0 0.0 2.0 2 0 0 2 2 2 1 DHH family BCDHK_Adom3 PF10436.9 ORX96227.1 - 0.042 13.7 0.0 0.092 12.6 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase DUF3328 PF11807.8 ORX96234.1 - 1.6e-40 139.2 0.6 2e-40 138.9 0.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) SR-25 PF10500.9 ORX96235.1 - 0.23 11.0 13.8 0.29 10.7 13.8 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RAP1 PF07218.11 ORX96235.1 - 2.3 6.4 8.4 2.3 6.4 8.4 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) ANAPC1 PF12859.7 ORX96235.1 - 2.6 8.6 11.0 3.3 8.3 11.0 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 1 DUF3328 PF11807.8 ORX96236.1 - 2.6e-30 105.8 1.7 2.8e-30 105.7 1.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Acetyltransf_10 PF13673.7 ORX96237.1 - 0.00017 21.5 0.0 0.00037 20.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ORX96237.1 - 0.00018 21.9 0.0 0.00033 21.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORX96237.1 - 0.00035 20.8 0.0 0.00056 20.1 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Myb_DNA-binding PF00249.31 ORX96237.1 - 0.068 13.4 0.1 0.21 11.8 0.1 1.8 1 0 0 1 1 1 0 Myb-like DNA-binding domain PIRT PF15099.6 ORX96238.1 - 0.49 10.0 7.2 0.034 13.7 1.7 1.9 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family AA_permease_2 PF13520.6 ORX96239.1 - 8.5e-44 150.0 64.4 1e-43 149.7 64.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ORX96239.1 - 2.3e-27 95.7 54.8 3.3e-27 95.2 54.8 1.1 1 0 0 1 1 1 1 Amino acid permease zf-C3HC4 PF00097.25 ORX96240.1 - 5e-09 35.9 6.8 5e-09 35.9 6.8 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORX96240.1 - 2.7e-08 34.0 7.4 2.7e-08 34.0 7.4 2.0 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 ORX96240.1 - 4.9e-07 29.7 4.8 4.9e-07 29.7 4.8 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 ORX96240.1 - 6.7e-06 25.9 7.8 6.7e-06 25.9 7.8 2.5 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 ORX96240.1 - 5.6e-05 23.3 5.7 0.00017 21.8 5.7 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 ORX96240.1 - 0.0001 22.4 7.3 0.0001 22.4 7.3 1.9 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 ORX96240.1 - 0.00015 21.5 8.0 0.00015 21.5 8.0 2.1 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORX96240.1 - 0.00034 20.5 6.1 0.00034 20.5 6.1 2.1 1 1 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 ORX96240.1 - 0.0029 17.4 8.5 0.0029 17.4 8.5 2.6 1 1 2 3 3 3 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 ORX96240.1 - 0.0054 16.8 4.4 0.012 15.6 4.4 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RNA_pol_L_2 PF13656.6 ORX96284.1 - 1.2e-07 31.4 0.5 1.5e-07 31.1 0.0 1.4 2 0 0 2 2 2 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 ORX96284.1 - 0.0044 16.4 0.0 0.0057 16.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Complex1_LYR_2 PF13233.6 ORX96285.1 - 1.1e-07 32.4 0.8 1.7e-07 31.9 0.8 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 ORX96285.1 - 8.4e-06 25.7 0.2 1.5e-05 24.9 0.2 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) G10 PF01125.17 ORX96286.1 - 6.2e-66 220.7 5.1 6.8e-66 220.5 5.1 1.0 1 0 0 1 1 1 1 G10 protein Cu_amine_oxid PF01179.20 ORX96289.1 - 5.1e-158 526.3 0.0 6.5e-158 525.9 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Mito_carr PF00153.27 ORX96289.1 - 3.1e-59 196.9 1.0 8.1e-20 70.6 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Cu_amine_oxidN3 PF02728.16 ORX96289.1 - 2.7e-20 72.6 0.1 6e-20 71.5 0.1 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 ORX96289.1 - 4.3e-12 46.1 0.0 7.4e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain GAIN_A PF18619.1 ORX96290.1 - 0.17 12.1 1.8 7.2 6.9 0.8 2.8 2 0 0 2 2 2 0 GPCR-Autoproteolysis-INducing (GAIN) subdomain A UQ_con PF00179.26 ORX96291.1 - 1.1e-28 99.6 0.0 2.4e-28 98.5 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme U-box PF04564.15 ORX96291.1 - 1.8e-20 72.9 1.2 7.1e-20 71.0 0.2 2.5 2 0 0 2 2 2 1 U-box domain VWA_2 PF13519.6 ORX96291.1 - 1.7e-08 35.1 0.1 1.4e-06 28.9 0.0 2.9 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.28 ORX96291.1 - 6.6e-08 33.0 1.9 1.5e-07 31.9 0.0 2.4 3 0 0 3 3 3 1 von Willebrand factor type A domain Ssl1 PF04056.14 ORX96291.1 - 0.016 15.0 0.0 0.034 13.9 0.0 1.5 1 0 0 1 1 1 0 Ssl1-like DUF4558 PF15104.6 ORX96291.1 - 0.018 15.1 3.2 0.042 13.9 3.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4558) zf-Nse PF11789.8 ORX96291.1 - 0.096 12.5 0.2 0.37 10.6 0.0 2.0 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit Tfb4 PF03850.14 ORX96291.1 - 0.13 11.7 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 Transcription factor Tfb4 DUF4913 PF16259.5 ORX96292.1 - 0.0017 18.4 0.3 1.3 9.2 0.0 3.0 3 0 0 3 3 3 2 Domain of unknown function (DUF4913) YkyA PF10368.9 ORX96292.1 - 0.097 12.3 0.4 0.32 10.7 0.0 1.9 3 0 0 3 3 3 0 Putative cell-wall binding lipoprotein DUF3437 PF11919.8 ORX96292.1 - 0.26 11.2 1.3 33 4.5 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3437) TPR_2 PF07719.17 ORX96293.1 - 3.4e-10 39.2 0.3 0.00085 19.3 0.1 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 ORX96293.1 - 5e-08 32.4 0.0 0.033 14.0 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 ORX96293.1 - 1.2e-05 25.8 0.0 0.013 16.2 0.1 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 ORX96293.1 - 2.8e-05 24.0 0.1 0.016 15.4 0.0 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 ORX96293.1 - 5.4e-05 23.4 0.1 0.095 13.0 0.2 3.1 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 ORX96293.1 - 0.0021 18.5 0.1 0.012 16.1 0.0 2.2 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 ORX96293.1 - 0.005 16.7 0.3 6.5 6.8 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 ORX96293.1 - 0.016 16.0 2.2 0.28 12.1 0.2 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 ORX96293.1 - 0.17 12.6 1.1 0.59 10.9 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 ORX96293.1 - 0.44 10.7 2.8 58 4.1 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Pho88 PF10032.9 ORX96294.1 - 7.1e-83 276.3 0.1 8.1e-83 276.1 0.1 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) DUF4408 PF14364.6 ORX96294.1 - 5.6 6.8 5.6 3.4 7.5 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4408) LIM PF00412.22 ORX96295.1 - 1.3e-19 70.1 41.9 9.8e-09 35.3 7.1 4.7 4 0 0 4 4 4 4 LIM domain Helo_like_N PF17111.5 ORX96295.1 - 5.3e-05 22.7 0.4 0.0001 21.7 0.4 1.5 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins SKG6 PF08693.10 ORX96296.1 - 2.5e-06 26.8 0.3 2.5e-06 26.8 0.3 1.8 2 0 0 2 2 2 1 Transmembrane alpha-helix domain DUF1180 PF06679.12 ORX96296.1 - 0.16 12.4 1.6 0.28 11.6 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) ATP-synt_Z PF16594.5 ORX96297.1 - 0.024 14.1 2.4 0.046 13.2 1.0 2.2 2 0 0 2 2 2 0 Putative AtpZ or ATP-synthase-associated UCH_1 PF13423.6 ORX96299.1 - 1.3e-15 57.8 0.0 7.1e-07 29.1 0.0 2.8 1 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUF4666 PF15697.5 ORX96299.1 - 0.21 12.3 4.9 1.2 9.8 4.9 2.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4666) Zip PF02535.22 ORX96299.1 - 0.88 8.7 7.6 1.8 7.7 7.6 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter FAM176 PF14851.6 ORX96299.1 - 0.96 9.1 5.6 19 4.9 5.3 2.7 2 0 0 2 2 2 0 FAM176 family Tim54 PF11711.8 ORX96299.1 - 1.8 7.3 9.7 0.037 12.8 2.3 1.9 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 FAM76 PF16046.5 ORX96299.1 - 3.5 6.9 11.8 8.8 5.6 11.8 1.6 1 0 0 1 1 1 0 FAM76 protein Ribosomal_L5_C PF00673.21 ORX96300.1 - 5.6e-27 93.7 0.0 4.1e-26 91.0 0.0 2.1 2 0 0 2 2 2 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 ORX96300.1 - 3.8e-10 40.0 0.0 7.1e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L5 SET PF00856.28 ORX96301.1 - 3.7e-12 47.0 0.0 1.1e-11 45.5 0.0 1.7 1 1 0 1 1 1 1 SET domain ATG101 PF07855.12 ORX96303.1 - 9.9e-56 188.0 0.3 1.1e-55 187.8 0.3 1.0 1 0 0 1 1 1 1 Autophagy-related protein 101 Mo-co_dimer PF03404.16 ORX96303.1 - 0.075 13.1 0.1 0.1 12.6 0.1 1.3 1 0 0 1 1 1 0 Mo-co oxidoreductase dimerisation domain Sugar_tr PF00083.24 ORX96304.1 - 8.9e-106 354.4 20.6 1.1e-105 354.1 20.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORX96304.1 - 8.3e-25 87.4 30.6 7.8e-18 64.5 7.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 ORX96304.1 - 0.00016 20.4 22.6 0.0022 16.6 3.1 3.0 2 1 1 3 3 3 2 MFS/sugar transport protein NACHT PF05729.12 ORX96342.1 - 6.5e-08 32.7 0.1 2e-07 31.1 0.1 1.9 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 ORX96342.1 - 5e-06 27.0 1.3 4.6e-05 23.9 0.0 3.1 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 ORX96342.1 - 9.4e-05 22.7 0.1 0.00085 19.6 0.0 2.7 2 1 0 2 2 2 1 AAA domain NB-ARC PF00931.22 ORX96342.1 - 0.00037 19.8 0.0 0.00094 18.4 0.0 1.7 1 0 0 1 1 1 1 NB-ARC domain KAP_NTPase PF07693.14 ORX96342.1 - 0.002 17.4 0.0 1.2 8.3 0.0 2.4 1 1 0 2 2 2 2 KAP family P-loop domain PPV_E1_C PF00519.17 ORX96342.1 - 0.0039 16.1 0.0 0.0068 15.3 0.0 1.3 1 0 0 1 1 1 1 Papillomavirus helicase zf-C2H2 PF00096.26 ORX96342.1 - 0.0091 16.4 1.0 0.052 14.0 0.2 2.7 2 0 0 2 2 2 1 Zinc finger, C2H2 type DUF2075 PF09848.9 ORX96342.1 - 0.01 15.1 0.2 0.031 13.5 0.2 1.8 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_33 PF13671.6 ORX96342.1 - 0.013 15.6 0.3 5.6 7.1 0.0 3.2 3 0 0 3 3 3 0 AAA domain APS_kinase PF01583.20 ORX96342.1 - 0.14 12.1 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase RNA_helicase PF00910.22 ORX96342.1 - 0.14 12.5 0.1 0.41 11.1 0.0 1.8 2 0 0 2 2 1 0 RNA helicase TagF_N PF09867.9 ORX96342.1 - 0.16 12.0 0.5 0.5 10.4 0.5 1.8 1 0 0 1 1 1 0 TagF N-terminal domain, Type VI secretion system-associated Band_7_C PF16200.5 ORX96342.1 - 0.18 11.8 0.1 0.37 10.9 0.1 1.5 1 0 0 1 1 1 0 C-terminal region of band_7 AAA_7 PF12775.7 ORX96342.1 - 0.2 11.2 0.0 0.34 10.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region zf-C2H2_4 PF13894.6 ORX96342.1 - 7.4 7.7 8.0 0.49 11.4 0.3 3.1 3 0 0 3 3 2 0 C2H2-type zinc finger SNF2_N PF00176.23 ORX96343.1 - 3.9e-63 213.3 0.0 5.3e-63 212.8 0.0 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ORX96343.1 - 1.1e-12 48.2 0.0 3e-12 46.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORX96343.1 - 1.2e-07 31.8 0.0 2e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 ORX96343.1 - 0.0032 17.2 0.0 0.014 15.1 0.0 1.9 1 1 0 1 1 1 1 SWI2/SNF2 ATPase ERCC3_RAD25_C PF16203.5 ORX96343.1 - 0.034 13.4 0.0 0.053 12.7 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase HET PF06985.11 ORX96344.1 - 4.8e-15 56.2 0.5 7.9e-15 55.5 0.1 1.7 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) TPR_2 PF07719.17 ORX96346.1 - 2.5e-15 55.3 1.5 0.0019 18.2 0.0 5.7 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_12 PF13424.6 ORX96346.1 - 2e-13 50.4 5.4 0.00067 19.9 0.0 4.2 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_7 PF13176.6 ORX96346.1 - 2e-10 40.0 0.1 0.0066 16.4 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 ORX96346.1 - 1.5e-09 37.2 0.4 0.018 14.9 0.0 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 ORX96346.1 - 9.9e-08 31.6 0.3 0.16 12.3 0.0 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 ORX96346.1 - 1.5e-07 31.0 8.5 0.0053 16.6 0.0 5.6 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 ORX96346.1 - 1.8e-06 28.2 0.5 1 10.1 0.0 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 ORX96346.1 - 2e-06 27.4 0.0 0.016 14.9 0.0 3.8 4 0 0 4 4 4 1 TPR repeat TPR_4 PF07721.14 ORX96346.1 - 2.1e-05 24.7 2.4 0.068 13.8 0.1 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 ORX96346.1 - 6.4e-05 23.5 1.6 1.4 9.7 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 ORX96346.1 - 0.00013 22.5 4.7 3 8.9 0.0 6.0 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_MalT PF17874.1 ORX96346.1 - 0.00066 19.1 1.5 0.0082 15.6 0.1 2.9 2 1 0 2 2 2 1 MalT-like TPR region TPR_19 PF14559.6 ORX96346.1 - 0.0023 18.4 0.3 44 4.7 0.0 4.2 4 1 1 5 5 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 ORX96346.1 - 0.03 14.5 0.6 0.5 10.6 0.1 2.8 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TIR PF01582.20 ORX96346.1 - 0.41 10.4 1.8 4.9 6.9 0.0 2.6 3 0 0 3 3 3 0 TIR domain ADIP PF11559.8 ORX96347.1 - 1.5e-45 155.0 10.5 4.2e-45 153.5 10.5 1.8 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding Golgin_A5 PF09787.9 ORX96347.1 - 0.00064 19.3 10.6 0.00064 19.3 10.6 1.7 2 0 0 2 2 2 1 Golgin subfamily A member 5 RepA_C PF04796.12 ORX96347.1 - 0.0094 16.0 0.4 0.02 14.9 0.4 1.5 1 0 0 1 1 1 1 Plasmid encoded RepA protein K_channel_TID PF07941.11 ORX96347.1 - 0.018 15.5 1.4 0.018 15.5 1.4 2.8 4 0 0 4 4 4 0 Potassium channel Kv1.4 tandem inactivation domain DUF724 PF05266.14 ORX96347.1 - 4.6 7.0 6.5 6.7 6.5 5.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF724) FUSC PF04632.12 ORX96347.1 - 9.9 4.6 8.1 21 3.5 8.1 1.5 1 0 0 1 1 1 0 Fusaric acid resistance protein family AMPK1_CBM PF16561.5 ORX96348.1 - 1.2e-05 25.4 0.1 2.7e-05 24.3 0.1 1.5 1 1 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase Siva PF05458.12 ORX96348.1 - 0.033 13.9 4.5 0.046 13.4 4.5 1.3 1 0 0 1 1 1 0 Cd27 binding protein (Siva) Nucleo_P87 PF07267.11 ORX96348.1 - 2 7.2 4.0 2.5 6.8 4.0 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Trep_Strep PF09605.10 ORX96349.1 - 0.13 12.2 0.1 0.27 11.2 0.0 1.5 2 0 0 2 2 2 0 Hypothetical bacterial integral membrane protein (Trep_Strep) BASP1 PF05466.12 ORX96349.1 - 8.5 6.3 15.8 16 5.4 15.8 1.4 1 0 0 1 1 1 0 Brain acid soluble protein 1 (BASP1 protein) DUF4724 PF15852.5 ORX96350.1 - 0.18 12.3 0.0 0.22 12.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4724) MBDa PF16564.5 ORX96352.1 - 0.09 13.0 0.1 0.21 11.8 0.1 1.6 1 0 0 1 1 1 0 p55-binding region of Methyl-CpG-binding domain proteins MBD DUF1657 PF07870.11 ORX96352.1 - 0.18 11.7 0.1 0.27 11.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1657) PET117 PF15786.5 ORX96354.1 - 2.4e-23 82.2 1.5 2.7e-23 82.0 1.5 1.0 1 0 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial V-ATPase_G PF03179.15 ORX96355.1 - 4.4e-32 110.8 16.0 4.9e-32 110.6 16.0 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit SHE3 PF17078.5 ORX96355.1 - 0.0029 17.4 4.3 0.0032 17.2 4.3 1.1 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 ATP-synt_B PF00430.18 ORX96355.1 - 0.018 15.1 11.2 0.018 15.1 11.2 2.0 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) V-ATPase_G_2 PF16999.5 ORX96355.1 - 0.14 12.6 13.0 0.2 12.1 13.0 1.3 1 1 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit ATP11 PF06644.11 ORX96355.1 - 0.15 11.9 10.4 0.17 11.6 10.4 1.0 1 0 0 1 1 1 0 ATP11 protein OmpH PF03938.14 ORX96355.1 - 0.29 11.5 14.5 0.34 11.2 14.5 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Drf_GBD PF06371.13 ORX96355.1 - 0.45 10.1 4.4 0.5 9.9 4.4 1.2 1 0 0 1 1 1 0 Diaphanous GTPase-binding Domain RRF PF01765.19 ORX96355.1 - 0.47 10.4 11.1 0.65 9.9 11.1 1.3 1 0 0 1 1 1 0 Ribosome recycling factor Ribosomal_S13 PF00416.22 ORX96355.1 - 0.49 10.8 5.6 2.6 8.5 0.2 2.1 1 1 1 2 2 2 0 Ribosomal protein S13/S18 DUF3450 PF11932.8 ORX96355.1 - 1.3 8.3 9.2 1.3 8.3 9.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF3552 PF12072.8 ORX96355.1 - 1.7 8.0 20.7 0.18 11.2 12.9 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) DUF676 PF05057.14 ORX96356.1 - 0.00087 18.9 0.1 0.0014 18.2 0.1 1.4 1 1 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 ORX96356.1 - 0.0067 16.2 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein LCAT PF02450.15 ORX96356.1 - 0.027 13.7 0.0 0.043 13.0 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Abhydrolase_1 PF00561.20 ORX96356.1 - 0.057 13.1 0.0 0.3 10.7 0.0 1.9 1 1 0 1 1 1 0 alpha/beta hydrolase fold Arrestin_N PF00339.29 ORX96357.1 - 1.8e-13 50.8 0.1 4e-11 43.2 0.0 2.9 3 1 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain Bul1_C PF04426.12 ORX96357.1 - 0.16 11.4 0.0 0.29 10.5 0.0 1.4 1 0 0 1 1 1 0 Bul1 C terminus SCP2 PF02036.17 ORX96359.1 - 1.1e-25 90.1 0.6 1.2e-25 89.9 0.6 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 ORX96359.1 - 1e-07 32.3 0.1 1.3e-07 32.0 0.1 1.1 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal MFS_1 PF07690.16 ORX96361.1 - 2.1e-34 119.0 37.0 2.1e-34 119.0 37.0 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORX96361.1 - 1.3e-10 40.8 9.6 1.3e-10 40.8 9.6 2.4 3 0 0 3 3 3 1 Sugar (and other) transporter Pkinase PF00069.25 ORX96384.1 - 3.6e-49 167.5 0.0 5.5e-49 166.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX96384.1 - 8.6e-28 97.3 0.5 3e-27 95.6 0.2 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORX96384.1 - 0.00031 19.7 0.1 0.00043 19.2 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 ORX96384.1 - 0.0022 17.3 0.1 0.0059 16.0 0.1 1.6 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.22 ORX96384.1 - 0.0042 16.7 0.2 0.012 15.2 0.2 1.8 1 1 0 1 1 1 1 RIO1 family Kdo PF06293.14 ORX96384.1 - 0.014 14.8 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 ORX96384.1 - 0.037 13.0 0.0 0.06 12.3 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH PF01636.23 ORX96384.1 - 0.091 12.7 0.1 0.19 11.6 0.1 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family DTHCT PF08070.11 ORX96384.1 - 1.4 9.7 5.8 2.7 8.7 5.8 1.4 1 0 0 1 1 1 0 DTHCT (NUC029) region Cyt-b5 PF00173.28 ORX96386.1 - 1.7e-12 47.3 0.0 2.2e-12 47.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Defensin_2 PF01097.18 ORX96387.1 - 0.31 11.0 1.5 0.63 10.0 1.5 1.5 1 0 0 1 1 1 0 Arthropod defensin DUF3425 PF11905.8 ORX96388.1 - 8e-13 48.5 0.8 1.7e-12 47.4 0.8 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) Zn_clus PF00172.18 ORX96388.1 - 1.6e-07 31.3 14.6 1.6e-07 31.3 14.6 2.4 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF5102 PF17104.5 ORX96388.1 - 0.092 12.8 1.4 0.13 12.2 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5102) Terpene_synth PF01397.21 ORX96388.1 - 0.096 12.4 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Terpene synthase, N-terminal domain SNF2_N PF00176.23 ORX96389.1 - 2.3e-06 26.6 0.0 0.04 12.6 0.0 2.3 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 ORX96389.1 - 0.027 14.8 0.0 0.063 13.6 0.0 1.6 1 0 0 1 1 1 0 Helicase conserved C-terminal domain YfhD PF14151.6 ORX96390.1 - 0.58 10.3 4.6 1.8 8.8 4.6 1.8 1 0 0 1 1 1 0 YfhD-like protein SIN1 PF05422.12 ORX96390.1 - 0.77 10.3 10.8 6 7.4 4.8 2.5 2 0 0 2 2 2 0 Stress-activated map kinase interacting protein 1 (SIN1) MRP-L46 PF11788.8 ORX96425.1 - 6.4e-38 130.2 0.0 1.4e-37 129.0 0.0 1.6 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 Cpn60_TCP1 PF00118.24 ORX96426.1 - 2e-152 508.3 11.0 2.3e-152 508.1 11.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family EAL PF00563.20 ORX96426.1 - 0.0057 16.2 0.0 0.013 15.1 0.0 1.5 1 0 0 1 1 1 1 EAL domain Nitro_FeMo-Co PF02579.17 ORX96426.1 - 0.007 16.7 0.0 0.025 14.9 0.0 1.9 1 0 0 1 1 1 1 Dinitrogenase iron-molybdenum cofactor TetR_C_14 PF17754.1 ORX96426.1 - 0.0076 16.2 0.4 0.73 9.8 0.1 2.4 2 0 0 2 2 2 1 MftR C-terminal domain Isy1 PF06246.12 ORX96427.1 - 4.9e-90 301.5 1.3 5.5e-90 301.4 1.3 1.0 1 0 0 1 1 1 1 Isy1-like splicing family DUF1788 PF08747.11 ORX96428.1 - 0.24 11.4 0.0 0.36 10.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1788) zf-C3HC4_3 PF13920.6 ORX96429.1 - 2.3e-07 30.5 6.6 4e-07 29.8 6.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORX96429.1 - 2.8e-07 30.4 6.6 5.7e-07 29.5 6.6 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-CCCH PF00642.24 ORX96429.1 - 2.9e-07 30.2 3.0 6.3e-07 29.1 3.0 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4 PF00097.25 ORX96429.1 - 4.1e-07 29.7 9.8 7.3e-07 29.0 9.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 ORX96429.1 - 9.2e-07 28.6 8.8 1.7e-06 27.8 8.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORX96429.1 - 6.9e-06 25.9 9.1 1.2e-05 25.2 9.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_10 PF16685.5 ORX96429.1 - 1.2e-05 25.3 4.5 1.2e-05 25.3 4.5 1.7 2 0 0 2 2 1 1 zinc RING finger of MSL2 zf-RING_2 PF13639.6 ORX96429.1 - 0.00013 22.2 7.7 0.00022 21.5 7.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf_CCCH_4 PF18345.1 ORX96429.1 - 0.00049 20.1 6.5 0.00097 19.1 6.5 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-C3HC4_4 PF15227.6 ORX96429.1 - 0.0032 17.6 7.5 0.0075 16.4 7.5 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 ORX96429.1 - 0.011 15.6 6.0 0.02 14.7 6.0 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-CCCH_4 PF18044.1 ORX96429.1 - 0.036 13.9 2.8 0.036 13.9 2.8 1.6 2 0 0 2 2 1 0 CCCH-type zinc finger zf-Nse PF11789.8 ORX96429.1 - 0.038 13.8 2.9 0.071 12.9 2.9 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-rbx1 PF12678.7 ORX96429.1 - 0.11 12.8 4.5 0.21 11.9 4.5 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-CCCH_2 PF14608.6 ORX96429.1 - 0.11 13.0 2.2 0.23 12.0 2.2 1.5 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger GnsAB_toxin PF08178.11 ORX96432.1 - 0.065 13.2 1.6 0.2 11.6 0.6 2.3 2 0 0 2 2 2 0 GnsA/GnsB toxin of bacterial toxin-antitoxin system Abhydrolase_6 PF12697.7 ORX96434.1 - 1.6e-11 45.2 1.4 2.1e-11 44.8 1.4 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORX96434.1 - 0.0038 16.5 0.0 0.0057 16.0 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ORX96434.1 - 0.029 14.0 0.0 0.052 13.2 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Ubiq_cyt_C_chap PF03981.12 ORX96435.1 - 9.9e-37 126.2 1.4 1.7e-36 125.4 0.9 1.5 2 0 0 2 2 2 1 Ubiquinol-cytochrome C chaperone GMC_oxred_N PF00732.19 ORX96436.1 - 6.1e-32 111.2 0.0 1.2e-28 100.4 0.0 3.1 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 ORX96436.1 - 5.7e-27 95.0 0.0 1.8e-26 93.4 0.0 1.8 2 0 0 2 2 2 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 ORX96436.1 - 0.00027 20.3 0.0 0.00056 19.2 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORX96436.1 - 0.0037 17.5 0.0 0.01 16.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 ORX96436.1 - 0.016 14.2 0.0 0.026 13.6 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 ORX96436.1 - 0.045 13.0 0.0 4 6.6 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ORX96436.1 - 0.091 11.8 0.1 0.17 11.0 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain PUF PF00806.19 ORX96437.1 - 7.1e-25 85.3 0.0 5.8e-05 22.5 0.0 6.1 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat RRM_1 PF00076.22 ORX96437.1 - 5.9e-13 48.4 0.0 1.3e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) YL1 PF05764.13 ORX96438.1 - 1.1e-59 202.5 30.7 1.1e-59 202.5 30.7 2.2 2 1 0 2 2 2 1 YL1 nuclear protein YL1_C PF08265.11 ORX96438.1 - 2.2e-07 30.5 0.1 3.8e-07 29.8 0.1 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain YqeY PF09424.10 ORX96438.1 - 1.3 9.1 8.9 2.7 8.1 8.9 1.4 1 0 0 1 1 1 0 Yqey-like protein DNA_pol_phi PF04931.13 ORX96438.1 - 4.8 5.2 9.2 7.7 4.5 9.2 1.2 1 0 0 1 1 1 0 DNA polymerase phi Ribosomal_S24e PF01282.19 ORX96439.1 - 1.4e-34 117.8 0.3 2.4e-34 117.1 0.1 1.5 1 1 0 1 1 1 1 Ribosomal protein S24e Methyltransf_16 PF10294.9 ORX96440.1 - 1.8e-19 70.1 0.0 2.9e-19 69.5 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 ORX96440.1 - 1.8e-06 27.6 0.1 2.8e-06 27.0 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 ORX96440.1 - 0.00016 21.2 0.0 0.00032 20.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Met_10 PF02475.16 ORX96440.1 - 0.014 15.2 0.0 0.024 14.4 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_25 PF13649.6 ORX96440.1 - 0.056 14.2 0.0 0.11 13.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Ecl1 PF12855.7 ORX96441.1 - 2.2e-37 129.9 23.3 2.2e-37 129.9 23.3 2.9 3 0 0 3 3 3 1 ECL1/2/3 zinc binding proteins zf-MYND PF01753.18 ORX96441.1 - 0.0027 17.7 0.6 0.0053 16.8 0.6 1.4 1 0 0 1 1 1 1 MYND finger zf-FLZ PF04570.14 ORX96441.1 - 0.048 13.1 3.9 0.26 10.8 3.9 2.0 1 1 0 1 1 1 0 zinc-finger of the FCS-type, C2-C2 zf_PR_Knuckle PF18445.1 ORX96441.1 - 0.07 13.0 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 PR zinc knuckle motif DUF2256 PF10013.9 ORX96441.1 - 0.81 9.9 5.3 0.45 10.7 1.2 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) Agouti PF05039.12 ORX96442.1 - 0.49 11.1 10.0 0.82 10.4 10.0 1.3 1 0 0 1 1 1 0 Agouti protein MFS_1 PF07690.16 ORX96462.1 - 1.5e-27 96.5 54.2 1.5e-27 96.5 54.2 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORX96462.1 - 3.3e-08 32.8 14.8 3.3e-08 32.8 14.8 3.0 2 1 0 2 2 2 1 Sugar (and other) transporter Helo_like_N PF17111.5 ORX96464.1 - 0.00078 18.9 0.4 0.0011 18.3 0.4 1.3 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins SesA PF17107.5 ORX96464.1 - 0.04 14.1 0.8 0.072 13.3 0.8 1.4 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Ank_4 PF13637.6 ORX96464.1 - 0.11 13.1 0.1 0.66 10.6 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeats (many copies) PCRF PF03462.18 ORX96464.1 - 0.15 11.9 0.2 0.28 11.0 0.2 1.3 1 0 0 1 1 1 0 PCRF domain Glyoxalase PF00903.25 ORX96466.1 - 4.3e-09 36.6 0.0 5e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Fungal_trans PF04082.18 ORX96467.1 - 1.5e-22 79.9 0.5 2.7e-22 79.1 0.2 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain ABC_tran_CTD PF16326.5 ORX96468.1 - 0.098 12.9 4.7 0.26 11.6 1.2 2.3 2 0 0 2 2 2 0 ABC transporter C-terminal domain DUF5082 PF16888.5 ORX96468.1 - 0.3 11.4 4.0 10 6.4 0.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) Ax_dynein_light PF10211.9 ORX96468.1 - 0.73 9.7 5.5 0.39 10.7 2.9 1.8 1 1 1 2 2 2 0 Axonemal dynein light chain APG6_N PF17675.1 ORX96468.1 - 5.2 7.6 10.7 2 9.0 6.7 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF2263 PF10021.9 ORX96469.1 - 1.6e-16 61.0 0.0 2.3e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) Macro PF01661.21 ORX96469.1 - 0.00072 19.6 0.0 0.0014 18.6 0.0 1.5 1 0 0 1 1 1 1 Macro domain Peptidase_S8 PF00082.22 ORX96470.1 - 3.1e-16 59.5 7.0 4.2e-16 59.1 7.0 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 ORX96470.1 - 2.2e-11 44.3 0.0 4.1e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 DAP_B PF07930.12 ORX96471.1 - 6.6e-68 228.3 0.0 9.1e-68 227.8 0.0 1.2 1 0 0 1 1 1 1 D-aminopeptidase, domain B Beta-lactamase PF00144.24 ORX96471.1 - 2.6e-41 142.0 0.0 4.1e-41 141.3 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase G_glu_transpept PF01019.21 ORX96495.1 - 1.9e-40 139.1 0.6 2.4e-40 138.8 0.6 1.1 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase PCRF PF03462.18 ORX96496.1 - 9.7e-50 169.1 0.0 2e-49 168.1 0.0 1.6 1 0 0 1 1 1 1 PCRF domain RF-1 PF00472.20 ORX96496.1 - 5e-33 113.5 1.7 1.1e-32 112.4 1.7 1.6 1 0 0 1 1 1 1 RF-1 domain MIR PF02815.19 ORX96496.1 - 0.015 15.1 0.3 0.049 13.5 0.2 1.5 1 1 0 1 1 1 0 MIR domain PDDEXK_1 PF12705.7 ORX96496.1 - 0.14 12.1 0.2 0.97 9.3 0.2 2.0 2 0 0 2 2 2 0 PD-(D/E)XK nuclease superfamily TRI12 PF06609.13 ORX96497.1 - 2.7e-24 85.6 25.5 3.6e-24 85.1 25.5 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 ORX96497.1 - 5.7e-13 48.5 61.7 1.3e-12 47.3 55.8 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily FeoB_C PF07664.12 ORX96497.1 - 0.21 11.3 1.7 0.8 9.4 0.1 3.0 2 0 0 2 2 2 0 Ferrous iron transport protein B C terminus DUF4618 PF15397.6 ORX96498.1 - 0.013 14.9 1.3 0.022 14.2 1.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) UPF0242 PF06785.11 ORX96498.1 - 0.041 14.0 0.9 0.094 12.8 0.9 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus betaPIX_CC PF16523.5 ORX96498.1 - 0.066 13.0 0.2 0.15 11.9 0.2 1.5 1 0 0 1 1 1 0 betaPIX coiled coil adh_short PF00106.25 ORX96500.1 - 7.4e-26 90.8 0.0 2e-25 89.4 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORX96500.1 - 2.6e-18 66.4 0.0 3.7e-18 65.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORX96500.1 - 7.5e-06 26.0 0.0 1.1e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ORX96500.1 - 0.0017 17.8 0.0 0.0023 17.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 ORX96500.1 - 0.16 11.0 0.0 0.24 10.5 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain Glyco_hydro_12 PF01670.16 ORX96501.1 - 7.8e-56 189.4 11.6 9.6e-56 189.1 11.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 TPR_12 PF13424.6 ORX96502.1 - 2.4e-09 37.4 21.8 1.9 8.8 0.0 9.7 10 0 0 10 10 10 4 Tetratricopeptide repeat AAA_22 PF13401.6 ORX96502.1 - 2.5e-07 31.0 0.1 2.5e-07 31.0 0.1 3.6 4 0 0 4 4 4 1 AAA domain AAA_16 PF13191.6 ORX96502.1 - 6.1e-05 23.5 0.0 0.00027 21.4 0.0 2.2 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 ORX96502.1 - 0.00024 21.0 3.2 0.00031 20.7 0.6 2.7 2 1 0 2 2 2 1 NACHT domain TPR_7 PF13176.6 ORX96502.1 - 0.11 12.6 14.6 35 4.8 0.0 8.0 7 0 0 7 7 7 0 Tetratricopeptide repeat AAA PF00004.29 ORX96502.1 - 0.17 12.3 0.7 1.1 9.7 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) TPR_10 PF13374.6 ORX96502.1 - 1.3 9.0 27.4 2.6 8.0 0.2 8.5 10 0 0 10 10 10 0 Tetratricopeptide repeat Sec1 PF00995.23 ORX96503.1 - 5.7e-128 428.6 0.0 6.5e-128 428.5 0.0 1.0 1 0 0 1 1 1 1 Sec1 family zf_CCCH_4 PF18345.1 ORX96504.1 - 7.3e-07 29.0 3.2 1.4e-06 28.1 3.2 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 ORX96504.1 - 2.2e-06 27.4 0.4 4.6e-06 26.4 0.4 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 ORX96504.1 - 4.4e-06 26.4 1.0 7.7e-06 25.6 1.0 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger Torus PF16131.5 ORX96504.1 - 4.9e-05 24.0 2.8 0.00012 22.7 2.8 1.7 1 0 0 1 1 1 1 Torus domain zf-CCCH_2 PF14608.6 ORX96504.1 - 0.00044 20.6 2.8 0.00093 19.6 2.8 1.6 1 0 0 1 1 1 1 RNA-binding, Nab2-type zinc finger TFIIA PF03153.13 ORX96504.1 - 0.0051 16.9 4.6 0.0051 16.9 4.6 3.5 3 1 0 3 3 3 1 Transcription factor IIA, alpha/beta subunit Dimerisation PF08100.11 ORX96504.1 - 0.044 13.8 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 Dimerisation domain zf-CCCH_3 PF15663.5 ORX96504.1 - 0.11 12.7 0.1 0.26 11.5 0.1 1.6 1 0 0 1 1 1 0 Zinc-finger containing family Cwf_Cwc_15 PF04889.12 ORX96504.1 - 3.6 7.2 11.7 4.5 6.9 1.5 2.8 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Btz PF09405.10 ORX96505.1 - 4.7e-28 98.0 0.8 1.1e-27 96.9 0.8 1.5 1 0 0 1 1 1 1 CASC3/Barentsz eIF4AIII binding SSP160 PF06933.11 ORX96507.1 - 7.5 4.6 16.4 8.8 4.4 16.4 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 TUDOR_5 PF18359.1 ORX96508.1 - 0.11 12.2 0.4 0.26 11.0 0.4 1.6 1 0 0 1 1 1 0 Histone methyltransferase Tudor domain 1 DUF2834 PF11196.8 ORX96510.1 - 1.6e-07 31.6 14.9 0.028 14.8 7.6 4.0 3 1 0 3 3 3 2 Protein of unknown function (DUF2834) Oxidored_q2 PF00420.24 ORX96510.1 - 1.1 9.0 3.8 5.7 6.6 0.1 2.5 2 1 1 3 3 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Aa_trans PF01490.18 ORX96511.1 - 7.5e-83 278.5 25.8 8.8e-83 278.3 25.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein zf-RING_2 PF13639.6 ORX96512.1 - 2e-06 28.0 12.6 2e-06 28.0 12.6 4.2 3 1 1 4 4 4 2 Ring finger domain DUF2089 PF09862.9 ORX96512.1 - 0.035 14.1 0.5 0.074 13.1 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2089) Glyco_hydro81C PF17652.1 ORX96514.1 - 5.9e-132 440.2 0.4 7.7e-132 439.8 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 ORX96514.1 - 6.3e-101 337.7 0.0 8.3e-101 337.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 N-terminal domain F-box-like PF12937.7 ORX96539.1 - 0.0059 16.5 0.3 0.033 14.1 0.3 2.4 1 1 0 1 1 1 1 F-box-like EB PF01683.18 ORX96540.1 - 0.29 11.5 3.7 0.47 10.8 3.7 1.3 1 0 0 1 1 1 0 EB module MSP1a PF11670.8 ORX96540.1 - 1.2 8.4 11.0 2.8 7.2 10.5 1.7 1 1 1 2 2 2 0 Major surface protein 1a (MSP1a) DUF2884 PF11101.8 ORX96543.1 - 0.16 11.4 0.5 4.9 6.6 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2884) Transp_cyt_pur PF02133.15 ORX96545.1 - 1e-14 54.2 16.1 2.4e-10 39.8 6.7 2.3 1 1 1 2 2 2 2 Permease for cytosine/purines, uracil, thiamine, allantoin MFS_1 PF07690.16 ORX96546.1 - 1.3e-40 139.4 33.1 2.7e-39 135.1 31.0 2.9 2 1 0 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 ORX96546.1 - 0.048 12.0 1.7 0.1 10.8 1.1 2.0 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.24 ORX96546.1 - 0.14 10.9 23.9 0.0076 15.2 8.6 3.0 2 1 1 3 3 3 0 Sugar (and other) transporter HlyIII PF03006.20 ORX96546.1 - 0.2 11.4 11.2 2.3 7.9 10.2 2.8 1 1 1 2 2 2 0 Haemolysin-III related p450 PF00067.22 ORX96547.1 - 1.9e-60 204.9 0.0 6.1e-51 173.6 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 Zn_clus PF00172.18 ORX96548.1 - 0.0049 17.0 8.2 0.0082 16.2 8.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Isochorismatase PF00857.20 ORX96549.1 - 3.5e-17 63.2 0.0 4.4e-17 62.8 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family HgmA PF04209.13 ORX96550.1 - 3.8e-104 348.8 1.9 4.7e-80 269.4 0.6 2.9 1 1 1 2 2 2 2 homogentisate 1,2-dioxygenase Pro_CA PF00484.19 ORX96552.1 - 1.7e-11 44.7 0.6 9e-10 39.1 0.6 2.1 1 1 0 1 1 1 1 Carbonic anhydrase SLATT_3 PF18184.1 ORX96552.1 - 0.13 12.4 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 3 DUF4231 PF14015.6 ORX96552.1 - 0.18 12.3 0.0 0.36 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) Yae1_N PF09811.9 ORX96553.1 - 0.028 14.1 4.8 0.023 14.4 2.8 2.0 2 0 0 2 2 2 0 Essential protein Yae1, N terminal Glyco_transf_8 PF01501.20 ORX96554.1 - 1e-11 44.9 0.1 2.5e-11 43.6 0.1 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 8 Nucleotid_trans PF03407.16 ORX96554.1 - 0.0038 17.2 0.1 0.0095 15.9 0.1 1.5 1 1 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Peroxin-3 PF04882.12 ORX96555.1 - 3.5e-170 567.0 0.1 4e-170 566.8 0.1 1.0 1 0 0 1 1 1 1 Peroxin-3 MCPVI PF02993.14 ORX96556.1 - 0.027 14.3 1.0 0.043 13.7 1.0 1.4 1 0 0 1 1 1 0 Minor capsid protein VI DEAD PF00270.29 ORX96557.1 - 7.4e-39 133.3 0.0 1.3e-38 132.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORX96557.1 - 5.9e-23 81.3 0.0 2e-21 76.4 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORX96557.1 - 1.7e-05 24.9 0.0 3.6e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 ORX96557.1 - 0.02 14.6 0.0 0.034 13.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain Carn_acyltransf PF00755.20 ORX96557.1 - 0.023 13.3 0.0 0.039 12.6 0.0 1.2 1 0 0 1 1 1 0 Choline/Carnitine o-acyltransferase ERCC3_RAD25_C PF16203.5 ORX96557.1 - 0.033 13.4 0.0 0.051 12.8 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase HET PF06985.11 ORX96558.1 - 1.5e-23 83.8 0.2 2.4e-23 83.1 0.2 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Amidase PF01425.21 ORX96559.1 - 2.5e-106 356.3 0.0 5.8e-106 355.2 0.0 1.5 1 1 0 1 1 1 1 Amidase RVT_1 PF00078.27 ORX96584.1 - 0.0089 15.6 0.6 0.01 15.4 0.6 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HET PF06985.11 ORX96586.1 - 9.7e-23 81.1 0.1 1.2e-22 80.8 0.1 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Thioredoxin PF00085.20 ORX96590.1 - 1.3e-26 92.5 0.2 1.7e-26 92.2 0.2 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 ORX96590.1 - 1.1e-06 28.8 0.0 0.00073 19.8 0.0 2.2 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.6 ORX96590.1 - 1.7e-05 25.2 0.1 6.3e-05 23.4 0.1 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.21 ORX96590.1 - 9.3e-05 22.3 0.1 0.0021 18.0 0.1 2.5 2 1 1 3 3 3 1 AhpC/TSA family Thioredoxin_9 PF14595.6 ORX96590.1 - 0.00018 21.3 0.0 0.00024 20.9 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 ORX96590.1 - 0.00021 20.8 0.0 0.00026 20.4 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 ORX96590.1 - 0.011 15.9 0.0 0.018 15.2 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like Redoxin PF08534.10 ORX96590.1 - 0.013 15.2 0.2 0.57 9.9 0.1 2.1 1 1 1 2 2 2 0 Redoxin Ntox47 PF15540.6 ORX96590.1 - 0.14 12.4 0.0 0.21 11.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial toxin 47 Na_Ca_ex PF01699.24 ORX96591.1 - 4.4e-19 68.9 32.3 1.3e-09 38.2 11.1 2.4 2 0 0 2 2 2 2 Sodium/calcium exchanger protein MAGE PF01454.19 ORX96591.1 - 0.13 11.9 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 MAGE family RIFIN PF02009.16 ORX96592.1 - 0.0007 19.6 2.1 0.00096 19.1 2.1 1.1 1 0 0 1 1 1 1 Rifin DUF948 PF06103.11 ORX96592.1 - 0.048 13.9 0.9 0.73 10.1 0.9 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) SLATT_5 PF18160.1 ORX96592.1 - 0.05 12.9 0.1 0.13 11.6 0.1 1.6 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 DUF202 PF02656.15 ORX96592.1 - 0.14 12.7 4.5 0.19 12.2 1.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF202) EphA2_TM PF14575.6 ORX96592.1 - 0.19 12.6 0.4 1.3 10.0 0.0 2.3 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain MGC-24 PF05283.11 ORX96592.1 - 0.47 10.9 15.3 0.66 10.4 12.2 2.6 2 1 1 3 3 3 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Adeno_E3_CR2 PF02439.15 ORX96592.1 - 1.3 8.8 11.6 0.23 11.2 1.7 2.4 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 DUF4064 PF13273.6 ORX96592.1 - 2.5 8.4 9.0 4.4e+02 1.2 9.0 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) MHYT PF03707.16 ORX96592.1 - 3 8.1 6.7 4.1 7.7 0.2 2.9 3 0 0 3 3 3 0 Bacterial signalling protein N terminal repeat Syndecan PF01034.20 ORX96592.1 - 8.2 6.4 7.1 0.54 10.2 0.4 2.1 2 0 0 2 2 2 0 Syndecan domain zf-PARP PF00645.18 ORX96593.1 - 7.2e-27 94.1 3.7 1.2e-12 48.5 0.1 2.8 3 0 0 3 3 3 2 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region AT_hook PF02178.19 ORX96593.1 - 0.058 13.3 5.1 0.18 11.8 5.1 1.9 1 0 0 1 1 1 0 AT hook motif Tantalus PF15386.6 ORX96593.1 - 0.1 12.7 0.5 0.27 11.3 0.5 1.7 1 0 0 1 1 1 0 Drosophila Tantalus-like Polyketide_cyc2 PF10604.9 ORX96594.1 - 1.9e-07 31.4 0.1 2.5e-07 31.1 0.1 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 ORX96594.1 - 0.00014 22.0 0.1 0.00029 21.0 0.1 1.6 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Pectinesterase PF01095.19 ORX96595.1 - 1.1e-50 172.1 10.2 1.4e-50 171.7 10.2 1.0 1 0 0 1 1 1 1 Pectinesterase DUF3060 PF11259.8 ORX96595.1 - 0.028 14.1 0.3 0.099 12.4 0.3 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3060) Mem_trans PF03547.18 ORX96598.1 - 5.2e-16 58.0 0.0 1.1e-15 57.0 0.0 1.5 1 1 0 1 1 1 1 Membrane transport protein FSH1 PF03959.13 ORX96599.1 - 8.5e-27 94.2 0.0 4.9e-26 91.7 0.0 1.9 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 ORX96599.1 - 5.8e-05 23.8 0.0 8.5e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 ORX96599.1 - 0.037 13.8 0.2 0.28 11.0 0.2 2.2 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase FSH1 PF03959.13 ORX96600.1 - 5.8e-17 62.1 0.0 9.4e-17 61.4 0.0 1.4 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Hydrolase_4 PF12146.8 ORX96600.1 - 0.079 12.2 0.0 0.082 12.2 0.0 1.1 1 0 0 1 1 1 0 Serine aminopeptidase, S33 MFS_1 PF07690.16 ORX96601.1 - 3.2e-35 121.7 56.6 7.9e-34 117.1 56.6 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily ketoacyl-synt PF00109.26 ORX96602.1 - 2.9e-71 240.0 0.0 5.3e-71 239.2 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 ORX96602.1 - 1.7e-59 200.7 0.3 3.8e-59 199.6 0.3 1.6 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.21 ORX96602.1 - 7e-50 170.3 0.0 1.3e-49 169.5 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 ORX96602.1 - 9.3e-49 166.3 0.0 1.8e-48 165.3 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 ORX96602.1 - 2.2e-36 124.5 0.4 5.9e-36 123.1 0.0 2.1 2 0 0 2 2 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.25 ORX96602.1 - 1.2e-12 47.8 0.1 2.7e-12 46.6 0.1 1.6 1 0 0 1 1 1 1 short chain dehydrogenase KAsynt_C_assoc PF16197.5 ORX96602.1 - 4.9e-11 43.1 0.0 1.3e-10 41.7 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension adh_short_C2 PF13561.6 ORX96602.1 - 5.1e-08 32.8 0.0 1.2e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase PP-binding PF00550.25 ORX96602.1 - 2.9e-06 27.5 0.1 1.1e-05 25.7 0.1 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.23 ORX96602.1 - 5.4e-06 26.0 0.0 1.2e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain ADH_zinc_N PF00107.26 ORX96602.1 - 0.0014 18.6 0.0 0.0048 16.9 0.0 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ORX96602.1 - 0.015 15.2 0.2 0.056 13.3 0.1 2.0 2 0 0 2 2 1 0 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 ORX96602.1 - 0.031 15.3 0.0 0.095 13.8 0.0 1.8 1 0 0 1 1 1 0 Zinc-binding dehydrogenase ACP_syn_III PF08545.10 ORX96602.1 - 0.12 12.2 0.1 0.45 10.4 0.1 2.0 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DUF3573 PF12097.8 ORX96603.1 - 0.027 13.3 0.4 0.076 11.8 0.1 1.7 1 1 0 2 2 2 0 Protein of unknown function (DUF3573) Spc7 PF08317.11 ORX96603.1 - 0.042 12.7 0.2 0.064 12.1 0.2 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF3382 PF11862.8 ORX96603.1 - 0.8 10.0 7.6 2 8.7 7.6 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3382) DUF5336 PF17270.2 ORX96603.1 - 0.94 9.1 6.5 3.1 7.4 2.4 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5336) DUF3087 PF11286.8 ORX96603.1 - 1.8 8.0 8.0 0.89 9.0 1.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3087) Peptidase_C14 PF00656.22 ORX96605.1 - 0.0004 20.4 0.0 0.0015 18.5 0.0 1.4 1 1 0 1 1 1 1 Caspase domain Ceramidase_alk PF04734.13 ORX96606.1 - 1e-107 360.9 0.0 1.2e-107 360.7 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 ORX96606.1 - 2.1e-59 200.2 0.0 3.1e-59 199.6 0.0 1.3 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal MFS_1 PF07690.16 ORX96635.1 - 2.1e-34 119.0 32.1 2.1e-34 119.0 32.1 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORX96635.1 - 2.7e-08 33.1 10.8 2.7e-08 33.1 10.8 2.2 3 1 0 3 3 3 1 Sugar (and other) transporter GFA PF04828.14 ORX96637.1 - 3.7e-17 62.4 4.5 9.6e-11 41.9 3.5 3.0 4 0 0 4 4 4 2 Glutathione-dependent formaldehyde-activating enzyme Rpr2 PF04032.16 ORX96637.1 - 0.00014 22.0 0.1 1.3 9.4 0.0 3.2 3 0 0 3 3 3 2 RNAse P Rpr2/Rpp21/SNM1 subunit domain NOB1_Zn_bind PF08772.11 ORX96637.1 - 0.037 14.2 3.1 2.8 8.2 1.1 2.8 2 1 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like RNA_POL_M_15KD PF02150.16 ORX96637.1 - 0.052 13.4 0.7 0.58 10.1 0.1 2.6 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit zf-NADH-PPase PF09297.11 ORX96637.1 - 3.7 7.3 17.9 1.5 8.5 0.3 4.2 4 0 0 4 4 4 0 NADH pyrophosphatase zinc ribbon domain HET PF06985.11 ORX96638.1 - 1.8e-32 112.7 2.7 4.6e-32 111.4 2.7 1.6 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Fungal_trans_2 PF11951.8 ORX96640.1 - 1.4e-08 34.0 1.2 1.4e-08 34.0 1.2 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORX96640.1 - 1.8e-07 31.2 9.9 3.5e-07 30.2 9.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_6 PF12697.7 ORX96641.1 - 2.7e-10 41.2 0.4 4.2e-10 40.6 0.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORX96641.1 - 3.9e-09 36.1 0.1 1.9e-08 33.9 0.0 1.9 2 0 0 2 2 2 1 Serine aminopeptidase, S33 LIP PF03583.14 ORX96641.1 - 2e-05 24.1 0.9 0.0019 17.6 0.6 2.2 2 0 0 2 2 2 2 Secretory lipase Abhydrolase_1 PF00561.20 ORX96641.1 - 4.6e-05 23.2 0.1 8.8e-05 22.3 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 ORX96641.1 - 0.00029 20.4 0.1 0.0031 17.0 0.1 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family DUF3089 PF11288.8 ORX96641.1 - 0.00061 19.4 0.0 0.001 18.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3089) Abhydrolase_3 PF07859.13 ORX96641.1 - 0.0084 16.0 0.1 0.016 15.1 0.1 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Palm_thioest PF02089.15 ORX96641.1 - 0.048 13.5 0.0 0.075 12.9 0.0 1.3 1 0 0 1 1 1 0 Palmitoyl protein thioesterase p450 PF00067.22 ORX96642.1 - 8e-35 120.5 0.0 2.1e-21 76.2 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 DUF621 PF04789.15 ORX96643.1 - 6.3e-05 22.3 1.9 6.3e-05 22.3 1.9 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF621) COX6C PF02937.15 ORX96643.1 - 0.17 12.0 1.6 0.34 11.1 0.1 2.3 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIc GWT1 PF06423.12 ORX96643.1 - 7.9 6.6 6.9 1 9.5 1.6 2.0 1 1 1 2 2 2 0 GWT1 Sugar_tr PF00083.24 ORX96644.1 - 4.8e-67 226.8 26.1 5.4e-67 226.6 26.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORX96644.1 - 1e-08 34.6 39.9 1.2e-08 34.3 33.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 ORX96644.1 - 0.38 9.6 13.6 0.058 12.3 5.4 2.5 2 0 0 2 2 2 0 MFS_1 like family Glyoxalase_3 PF13468.6 ORX96645.1 - 2.5e-06 27.7 0.0 9.2e-06 25.9 0.0 1.8 2 0 0 2 2 2 1 Glyoxalase-like domain Glyoxalase_4 PF13669.6 ORX96645.1 - 1.3e-05 25.4 0.1 0.00033 20.9 0.0 2.6 2 1 1 3 3 3 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily WD40 PF00400.32 ORX96646.1 - 0.00013 22.7 0.3 0.0015 19.3 0.1 2.9 2 0 0 2 2 2 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX96646.1 - 0.0015 18.8 0.1 11 6.3 0.0 3.8 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ PF01011.21 ORX96646.1 - 0.059 13.3 0.1 0.21 11.6 0.1 2.1 1 0 0 1 1 1 0 PQQ enzyme repeat DUF5114 PF17141.4 ORX96646.1 - 0.14 12.7 0.4 5.1 7.7 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF5114) NICE-1 PF15845.5 ORX96647.1 - 0.0073 17.0 1.0 0.035 14.9 0.0 2.4 2 0 0 2 2 2 1 Cysteine-rich C-terminal 1 family Oxidored_molyb PF00174.19 ORX96648.1 - 1.2e-46 158.5 0.0 1.7e-46 157.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 ORX96648.1 - 6.5e-17 61.8 1.2 1.1e-16 61.1 1.2 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain ACOX PF01756.19 ORX96649.1 - 2.4e-46 157.6 0.0 4.1e-46 156.8 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 ORX96649.1 - 5.3e-16 59.3 0.0 8.8e-16 58.6 0.0 1.4 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 ORX96649.1 - 3.4e-06 27.2 0.0 7.6e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 ORX96649.1 - 8.5e-06 26.0 0.2 1.6e-05 25.2 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain PAN_4 PF14295.6 ORX96651.1 - 0.14 12.1 1.8 0.36 10.8 1.8 1.6 1 0 0 1 1 1 0 PAN domain Alpha_L_fucos PF01120.17 ORX96652.1 - 2.6e-87 293.5 1.4 3.5e-87 293.1 1.4 1.1 1 0 0 1 1 1 1 Alpha-L-fucosidase Fungal_trans_2 PF11951.8 ORX96653.1 - 5.7e-06 25.4 0.2 1.4e-05 24.1 0.2 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain HET PF06985.11 ORX96676.1 - 3.1e-29 102.2 0.1 7.8e-29 100.9 0.1 1.6 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HET PF06985.11 ORX96679.1 - 2.6e-08 34.4 3.8 6.1e-06 26.7 0.9 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) S6PP_C PF08472.10 ORX96679.1 - 0.07 13.0 1.0 0.73 9.7 0.7 2.1 1 1 1 2 2 2 0 Sucrose-6-phosphate phosphohydrolase C-terminal DnaJ PF00226.31 ORX96682.1 - 6.5e-18 64.6 1.1 1.3e-17 63.7 1.1 1.6 1 0 0 1 1 1 1 DnaJ domain Ank_4 PF13637.6 ORX96683.1 - 1.8e-19 69.8 0.3 2e-10 41.0 0.1 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 ORX96683.1 - 1.3e-13 51.3 0.5 2.5e-13 50.4 0.5 1.5 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 ORX96683.1 - 5.8e-13 48.6 5.5 0.00013 22.2 0.1 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 ORX96683.1 - 6e-10 38.5 0.2 0.0088 16.5 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 ORX96683.1 - 1.6e-07 31.5 6.8 0.00098 19.4 0.3 2.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Phosphonate-bd PF12974.7 ORX96683.1 - 0.063 12.9 1.0 1.8 8.1 1.0 2.1 1 1 0 1 1 1 0 ABC transporter, phosphonate, periplasmic substrate-binding protein VWA_3_C PF18571.1 ORX96683.1 - 0.065 13.1 5.0 15 5.6 0.1 3.1 3 0 0 3 3 3 0 von Willebrand factor type A C-terminal domain HTH_16 PF12645.7 ORX96683.1 - 0.23 11.5 0.3 60 3.8 0.0 3.0 3 0 0 3 3 3 0 Helix-turn-helix domain NACHT PF05729.12 ORX96684.1 - 0.014 15.4 0.1 0.026 14.4 0.1 1.6 1 1 0 1 1 1 0 NACHT domain AAA_22 PF13401.6 ORX96684.1 - 0.15 12.3 0.2 0.86 9.9 0.1 2.1 2 1 0 2 2 2 0 AAA domain Helo_like_N PF17111.5 ORX96685.1 - 0.07 12.5 0.1 0.1 12.0 0.1 1.4 1 1 0 1 1 1 0 Fungal N-terminal domain of STAND proteins SesA PF17107.5 ORX96685.1 - 0.091 13.0 0.1 0.33 11.1 0.0 1.8 1 1 1 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases NmrA PF05368.13 ORX96688.1 - 8e-28 97.6 0.1 1e-27 97.2 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ORX96688.1 - 1e-16 61.4 0.0 1.6e-16 60.7 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 ORX96688.1 - 2.7e-05 24.5 0.1 9.5e-05 22.7 0.0 1.8 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain 3Beta_HSD PF01073.19 ORX96688.1 - 0.0045 16.0 0.0 0.0074 15.3 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Shikimate_DH PF01488.20 ORX96688.1 - 0.064 13.3 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Ank_4 PF13637.6 ORX96690.1 - 0.00086 19.8 0.0 0.019 15.5 0.0 2.6 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 ORX96690.1 - 0.0017 18.9 0.1 0.01 16.4 0.1 2.1 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Astro_capsid_p PF12226.8 ORX96691.1 - 0.069 12.3 0.3 0.096 11.8 0.3 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Macro_2 PF14519.6 ORX96711.1 - 1.5e-05 24.5 0.0 1.8e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Macro-like domain Macro PF01661.21 ORX96711.1 - 0.15 12.1 0.0 24 5.0 0.0 2.3 2 0 0 2 2 2 0 Macro domain Mid2 PF04478.12 ORX96712.1 - 0.087 12.7 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor TTC5_OB PF16669.5 ORX96712.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat protein 5 OB fold domain CMAS PF02353.20 ORX96713.1 - 1.1e-39 136.4 0.0 1.4e-39 136.1 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 ORX96713.1 - 5.4e-09 36.1 0.0 8.7e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORX96713.1 - 2.3e-08 34.7 0.0 4.5e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORX96713.1 - 5.2e-08 33.4 0.0 1.3e-07 32.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORX96713.1 - 9.8e-07 29.4 0.0 2.2e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORX96713.1 - 0.16 11.7 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Condensation PF00668.20 ORX96714.1 - 0 2665.6 0.0 6.1e-89 298.8 0.0 12.1 12 0 0 12 12 12 12 Condensation domain AMP-binding PF00501.28 ORX96714.1 - 0 2324.4 5.0 3.9e-74 249.8 0.0 10.2 10 0 0 10 10 10 10 AMP-binding enzyme PP-binding PF00550.25 ORX96714.1 - 4.1e-131 427.5 30.4 1.1e-14 54.5 0.1 11.2 10 0 0 10 10 10 10 Phosphopantetheine attachment site AMP-binding_C PF13193.6 ORX96714.1 - 2.5e-82 271.9 21.4 5.2e-11 43.4 0.2 14.4 13 0 0 13 13 13 11 AMP-binding enzyme C-terminal domain Methyltransf_23 PF13489.6 ORX96714.1 - 8.6e-16 58.2 0.0 0.00095 19.0 0.0 4.9 5 0 0 5 5 5 3 Methyltransferase domain Methyltransf_25 PF13649.6 ORX96714.1 - 1.4e-15 57.8 0.0 0.0013 19.4 0.0 5.0 4 0 0 4 4 4 3 Methyltransferase domain Methyltransf_11 PF08241.12 ORX96714.1 - 2.4e-13 50.6 0.0 0.011 16.3 0.0 5.0 4 0 0 4 4 3 3 Methyltransferase domain Methyltransf_12 PF08242.12 ORX96714.1 - 2e-11 44.5 0.0 0.026 15.2 0.0 4.9 5 0 0 5 5 4 3 Methyltransferase domain DUF547 PF04784.14 ORX96714.1 - 2.2e-10 40.6 0.5 4 7.5 0.0 9.2 9 0 0 9 9 9 1 Protein of unknown function, DUF547 Methyltransf_31 PF13847.6 ORX96714.1 - 5.2e-07 29.6 0.0 0.21 11.4 0.0 3.9 4 0 0 4 4 4 2 Methyltransferase domain Pirin_C PF05726.13 ORX96714.1 - 0.026 14.9 1.0 1.5e+02 2.8 0.0 6.0 6 0 0 6 6 6 0 Pirin C-terminal cupin domain DUF502 PF04367.13 ORX96714.1 - 0.19 11.7 0.3 15 5.5 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF502) CPSase_L_D2 PF02786.17 ORX96714.1 - 1.4 8.4 6.8 1.4e+02 1.8 0.0 5.7 7 0 0 7 7 7 0 Carbamoyl-phosphate synthase L chain, ATP binding domain RTC4 PF14474.6 ORX96748.1 - 1.9e-28 99.0 0.0 2.7e-28 98.6 0.0 1.2 1 0 0 1 1 1 1 RTC4-like domain RTC_insert PF05189.13 ORX96750.1 - 1.2e-32 112.5 0.0 2.6e-32 111.4 0.0 1.6 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain RTC PF01137.21 ORX96750.1 - 1.2e-24 86.8 0.0 3.7e-24 85.2 0.0 1.6 1 1 0 1 1 1 1 RNA 3'-terminal phosphate cyclase Peptidase_S8 PF00082.22 ORX96751.1 - 9.7e-35 120.3 1.3 1.4e-34 119.8 1.3 1.2 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 ORX96751.1 - 1.4e-28 98.8 0.2 3.1e-28 97.6 0.2 1.7 1 0 0 1 1 1 1 Proprotein convertase P-domain S8_pro-domain PF16470.5 ORX96751.1 - 0.00068 20.4 0.4 0.0015 19.3 0.4 1.6 1 0 0 1 1 1 1 Peptidase S8 pro-domain Mucin PF01456.17 ORX96751.1 - 0.082 12.9 4.0 0.16 12.0 4.0 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein PhoD PF09423.10 ORX96752.1 - 4e-08 32.7 0.2 5.2e-07 29.0 0.2 2.1 1 1 0 1 1 1 1 PhoD-like phosphatase Glyco_hydro_61 PF03443.14 ORX96753.1 - 1e-37 130.1 0.0 1.2e-37 129.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 adh_short PF00106.25 ORX96754.1 - 8.4e-11 41.7 0.0 5.6e-07 29.2 0.1 2.7 2 1 1 3 3 3 2 short chain dehydrogenase KR PF08659.10 ORX96754.1 - 1.3e-05 25.1 0.1 2.1e-05 24.5 0.1 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 ORX96754.1 - 0.044 13.3 0.0 0.58 9.7 0.0 2.1 2 0 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase HET PF06985.11 ORX96758.1 - 1.7e-17 64.1 0.0 2.1e-17 63.8 0.0 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) zf-C2H2_2 PF12756.7 ORX96759.1 - 2.5e-24 85.5 4.0 2e-22 79.4 0.2 2.4 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) SAGA-Tad1 PF12767.7 ORX96759.1 - 0.06 13.1 3.1 0.032 14.0 1.0 1.6 1 1 1 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit zf-UBP PF02148.19 ORX96759.1 - 0.11 12.9 4.5 4.2 7.8 0.2 3.2 3 0 0 3 3 3 0 Zn-finger in ubiquitin-hydrolases and other protein zf-C2H2_4 PF13894.6 ORX96759.1 - 0.35 11.8 13.4 1.2 10.2 0.3 3.9 3 1 0 3 3 3 0 C2H2-type zinc finger VIR_N PF15912.5 ORX96759.1 - 1.9 8.0 5.3 3.3 7.2 5.3 1.3 1 0 0 1 1 1 0 Virilizer, N-terminal Glyco_hydro_115 PF15979.5 ORX96760.1 - 5.9e-108 361.3 0.2 4.5e-107 358.4 0.2 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 115 GH115_C PF17829.1 ORX96760.1 - 9.5e-42 142.7 0.0 2.2e-41 141.6 0.0 1.6 1 0 0 1 1 1 1 Gylcosyl hydrolase family 115 C-terminal domain TMEM189_B_dmain PF10520.9 ORX96760.1 - 0.096 12.8 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 B domain of TMEM189, localisation domain Glyoxalase PF00903.25 ORX96761.1 - 1.2e-11 44.9 3.6 2.6e-11 43.8 1.7 2.1 2 0 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 ORX96761.1 - 1.9e-06 28.1 0.1 1.5e-05 25.2 0.1 2.2 2 0 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily FAD_binding_3 PF01494.19 ORX96762.1 - 4.8e-40 137.9 0.0 1.6e-39 136.2 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 ORX96762.1 - 2.3e-05 23.8 0.4 7.8e-05 22.1 0.3 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 ORX96762.1 - 0.0012 18.1 0.0 0.0025 17.1 0.0 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 ORX96762.1 - 0.0018 17.4 0.2 0.0028 16.8 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 ORX96762.1 - 0.003 16.8 0.1 0.0052 16.0 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORX96762.1 - 0.0061 16.8 0.0 0.016 15.5 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ORX96762.1 - 0.014 15.0 0.1 0.029 13.9 0.1 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 ORX96762.1 - 0.03 13.0 0.0 0.046 12.4 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Lycopene_cycl PF05834.12 ORX96762.1 - 0.033 13.2 0.3 0.41 9.6 0.1 2.4 3 0 0 3 3 3 0 Lycopene cyclase protein Phytochelatin PF05023.14 ORX96762.1 - 0.048 12.9 0.0 0.091 12.0 0.0 1.3 1 0 0 1 1 1 0 Phytochelatin synthase FAA_hydrolase PF01557.18 ORX96763.1 - 1.2e-55 188.6 0.0 1.4e-55 188.4 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Fungal_trans PF04082.18 ORX96764.1 - 5.5e-12 45.3 1.1 8.8e-12 44.6 1.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_16 PF00722.21 ORX96793.1 - 9.8e-43 145.7 2.2 1.5e-42 145.0 2.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Chitin_bind_1 PF00187.19 ORX96793.1 - 0.071 13.6 5.6 0.17 12.4 5.6 1.6 1 0 0 1 1 1 0 Chitin recognition protein HET PF06985.11 ORX96794.1 - 1.9e-24 86.7 0.1 4.6e-24 85.4 0.1 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Kp4 PF09044.10 ORX96797.1 - 2.2e-15 56.8 0.0 4e-15 56.0 0.0 1.4 1 0 0 1 1 1 1 Kp4 RRXRR PF14239.6 ORX96798.1 - 0.19 11.5 8.3 0.25 11.2 8.3 1.2 1 0 0 1 1 1 0 RRXRR protein TRP PF06011.12 ORX96799.1 - 8.2e-40 136.8 19.7 1.4e-37 129.5 19.7 2.1 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 ORX96799.1 - 4.9e-20 72.3 0.2 7.2e-20 71.8 0.2 1.3 1 0 0 1 1 1 1 ML-like domain FYVE PF01363.21 ORX96800.1 - 1.2e-21 76.5 2.0 1.2e-21 76.5 2.0 3.2 3 0 0 3 3 3 1 FYVE zinc finger zf-RING_2 PF13639.6 ORX96800.1 - 1e-05 25.8 4.2 1e-05 25.8 4.2 3.3 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.6 ORX96800.1 - 2.9e-05 23.8 2.0 2.9e-05 23.8 2.0 3.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORX96800.1 - 0.0005 19.9 1.0 0.0005 19.9 1.0 3.6 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 ORX96800.1 - 0.0063 16.2 6.3 0.0099 15.6 4.6 2.3 2 0 0 2 2 2 1 RING-like zinc finger FYVE_2 PF02318.16 ORX96800.1 - 0.0098 16.1 0.6 0.0098 16.1 0.6 2.2 2 0 0 2 2 2 1 FYVE-type zinc finger Rad50_zn_hook PF04423.14 ORX96800.1 - 0.12 12.3 2.6 4.7 7.1 0.1 2.3 2 0 0 2 2 2 0 Rad50 zinc hook motif Opy2 PF09463.10 ORX96800.1 - 0.5 10.7 5.7 0.46 10.8 1.6 2.7 2 0 0 2 2 2 0 Opy2 protein zinc_ribbon_2 PF13240.6 ORX96800.1 - 0.52 10.1 7.8 4 7.3 0.3 3.4 3 0 0 3 3 3 0 zinc-ribbon domain HypA PF01155.19 ORX96800.1 - 2.5 8.2 4.2 3.6 7.7 1.8 2.2 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 ORX96800.1 - 2.5 8.2 15.1 4.7 7.3 0.3 3.2 3 0 0 3 3 3 0 Double zinc ribbon zf-B_box PF00643.24 ORX96800.1 - 4.8 7.4 11.4 2.5 8.3 6.2 3.0 2 0 0 2 2 2 0 B-box zinc finger TF_Zn_Ribbon PF08271.12 ORX96800.1 - 7.3 6.2 9.8 3.6 7.2 4.1 2.6 2 1 0 2 2 2 0 TFIIB zinc-binding Fungal_trans PF04082.18 ORX96802.1 - 1.7e-15 56.8 0.1 1.3e-14 53.8 0.0 2.3 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORX96802.1 - 6.9e-06 26.1 16.4 1.6e-05 24.9 16.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RNB PF00773.19 ORX96804.1 - 1.1e-58 199.2 0.0 8.9e-58 196.1 0.0 2.1 1 1 0 1 1 1 1 RNB domain ThiS PF02597.20 ORX96805.1 - 3.8e-10 40.2 0.0 6e-10 39.6 0.0 1.3 1 1 0 1 1 1 1 ThiS family Zn_clus PF00172.18 ORX96806.1 - 1.6e-05 24.9 14.1 2.5e-05 24.3 14.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ORX96806.1 - 3.1e-05 23.1 0.3 0.0001 21.4 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain MerR-DNA-bind PF09278.11 ORX96806.1 - 0.19 12.3 1.2 0.3 11.7 0.1 1.9 2 0 0 2 2 2 0 MerR, DNA binding FAD_binding_7 PF03441.14 ORX96807.1 - 1.9e-72 243.0 0.1 3.4e-72 242.2 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 ORX96807.1 - 2.7e-38 131.5 0.0 5.4e-38 130.6 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase Glyco_hydro_115 PF15979.5 ORX96808.1 - 3.9e-140 467.1 6.8 5.8e-140 466.5 6.8 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 115 GH115_C PF17829.1 ORX96808.1 - 3.5e-49 166.9 0.0 8.2e-49 165.7 0.0 1.7 1 0 0 1 1 1 1 Gylcosyl hydrolase family 115 C-terminal domain S_layer_C PF05124.12 ORX96808.1 - 0.037 14.0 0.3 0.061 13.3 0.3 1.3 1 0 0 1 1 1 0 S-layer like family, C-terminal region DUF2462 PF09495.10 ORX96809.1 - 8.6e-11 42.4 7.8 9.2e-11 42.3 7.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2462) DUF5427 PF10310.9 ORX96810.1 - 2.7e-171 570.6 0.0 3.4e-171 570.3 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5427) Flu_M1_C PF08289.11 ORX96810.1 - 0.035 14.3 0.1 0.11 12.7 0.1 1.8 1 0 0 1 1 1 0 Influenza Matrix protein (M1) C-terminal domain SARAF PF06682.12 ORX96810.1 - 2.5 7.7 9.9 0.77 9.3 6.2 1.8 1 1 1 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis Ndc1_Nup PF09531.10 ORX96810.1 - 6.5 5.3 5.0 8.2 5.0 5.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DNA_pol_phi PF04931.13 ORX96811.1 - 0.45 8.6 11.0 1.5 6.8 1.9 2.2 2 0 0 2 2 2 0 DNA polymerase phi BTB PF00651.31 ORX96834.1 - 2.5e-07 30.9 0.0 3.8e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Aspzincin_M35 PF14521.6 ORX96836.1 - 8.6e-08 32.8 0.9 2.4e-07 31.4 0.9 1.8 1 1 0 1 1 1 1 Lysine-specific metallo-endopeptidase AAA PF00004.29 ORX96837.1 - 1.3e-18 67.6 0.0 2.9e-18 66.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 ORX96837.1 - 0.00039 20.7 0.1 0.0052 17.1 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 ORX96837.1 - 0.0005 20.5 1.4 0.0033 17.8 1.2 2.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 ORX96837.1 - 0.0024 17.9 0.0 0.0047 16.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 ORX96837.1 - 0.0087 16.2 0.0 0.032 14.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 ORX96837.1 - 0.018 15.2 0.0 0.041 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 ORX96837.1 - 0.048 13.4 0.0 0.15 11.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain Zot PF05707.12 ORX96837.1 - 0.05 13.2 0.1 0.41 10.2 0.0 2.1 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) AAA_25 PF13481.6 ORX96837.1 - 0.057 13.0 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 ORX96837.1 - 0.096 13.2 0.0 0.27 11.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 ORX96837.1 - 0.14 11.9 0.0 0.31 10.8 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain NPV_P10 PF05531.12 ORX96838.1 - 0.026 15.0 0.3 2.6 8.6 0.1 3.5 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Goodbye PF17109.5 ORX96838.1 - 0.03 14.8 0.4 2.1 8.8 0.0 3.0 3 1 0 3 3 3 0 fungal STAND N-terminal Goodbye domain Med9 PF07544.13 ORX96838.1 - 0.045 13.8 0.1 0.2 11.8 0.1 2.2 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 CAP_N PF01213.19 ORX96838.1 - 0.13 11.7 3.8 0.083 12.4 0.3 2.4 4 0 0 4 4 4 0 Adenylate cyclase associated (CAP) N terminal Spore_II_R PF09551.10 ORX96838.1 - 0.33 11.4 3.1 0.23 11.9 0.5 2.1 2 0 0 2 2 2 0 Stage II sporulation protein R (spore_II_R) GLTP PF08718.11 ORX96838.1 - 2.1 8.6 4.3 11 6.3 0.5 3.0 1 1 1 3 3 3 0 Glycolipid transfer protein (GLTP) FlaC_arch PF05377.11 ORX96838.1 - 2.7 8.5 4.9 1.9 8.9 0.8 2.9 2 1 2 4 4 4 0 Flagella accessory protein C (FlaC) Cation_efflux PF01545.21 ORX96839.1 - 2.3e-49 167.9 7.4 2.9e-49 167.5 7.4 1.1 1 0 0 1 1 1 1 Cation efflux family BPD_transp_2 PF02653.16 ORX96839.1 - 0.00015 21.0 1.3 0.00015 21.0 1.3 2.6 2 1 1 3 3 3 1 Branched-chain amino acid transport system / permease component zf-met2 PF12907.7 ORX96840.1 - 9.2e-11 41.7 3.3 1.5e-10 41.1 3.3 1.3 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.14 ORX96840.1 - 2.1e-06 28.5 10.5 2.1e-06 28.5 10.5 1.7 2 0 0 2 2 2 1 4F5 protein family DUF2688 PF10892.8 ORX96840.1 - 0.019 14.4 0.0 0.027 13.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2688) DDOST_48kD PF03345.14 ORX96841.1 - 1.8e-154 514.6 0.0 2.1e-154 514.4 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta BTB PF00651.31 ORX96843.1 - 0.0053 17.0 0.0 0.12 12.6 0.0 2.3 2 0 0 2 2 2 1 BTB/POZ domain GST_N_2 PF13409.6 ORX96844.1 - 2.1e-20 72.8 0.0 3.9e-20 71.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 ORX96844.1 - 6.3e-08 32.5 0.0 2e-07 31.0 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 ORX96844.1 - 0.0042 17.2 0.0 0.0084 16.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 ORX96844.1 - 0.025 15.0 0.0 8.3 6.9 0.0 2.5 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain RTA1 PF04479.13 ORX96845.1 - 1.7e-24 86.6 1.7 2.1e-24 86.3 1.7 1.0 1 0 0 1 1 1 1 RTA1 like protein Lectin_N PF03954.14 ORX96845.1 - 0.085 12.6 0.1 0.12 12.1 0.1 1.2 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain Clathrin_lg_ch PF01086.17 ORX96846.1 - 1.8e-75 254.0 0.0 2e-75 253.8 0.0 1.0 1 0 0 1 1 1 1 Clathrin light chain rve_3 PF13683.6 ORX96846.1 - 0.013 15.3 0.4 0.028 14.2 0.4 1.5 1 0 0 1 1 1 0 Integrase core domain VitK2_biosynth PF02621.14 ORX96846.1 - 0.065 12.7 0.1 0.091 12.3 0.1 1.2 1 0 0 1 1 1 0 Menaquinone biosynthesis Tgi2PP PF18250.1 ORX96846.1 - 0.93 9.8 5.1 24 5.3 0.1 3.6 4 0 0 4 4 4 0 Effector immunity protein Tgi2PP CTD_bind PF04818.13 ORX96847.1 - 6.7e-15 55.7 0.3 1.7e-14 54.3 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase II-binding domain. CDC37_N PF03234.14 ORX96848.1 - 9.4e-49 165.6 0.8 9.4e-49 165.6 0.8 2.4 3 0 0 3 3 3 1 Cdc37 N terminal kinase binding CDC37_M PF08565.11 ORX96848.1 - 2.4e-43 146.8 0.1 2.5e-42 143.5 0.1 2.4 2 0 0 2 2 2 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.10 ORX96848.1 - 2.2e-30 104.7 2.1 6.5e-30 103.2 0.1 2.6 3 0 0 3 3 3 1 Cdc37 C terminal domain MecA_N PF05223.11 ORX96848.1 - 0.0073 16.6 0.3 0.2 11.9 0.0 2.7 2 0 0 2 2 2 1 NTF2-like N-terminal transpeptidase domain GFA PF04828.14 ORX96849.1 - 1.1e-14 54.5 2.3 1.9e-14 53.7 2.3 1.4 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Glyco_hydro_61 PF03443.14 ORX96850.1 - 8.8e-64 215.2 0.2 1.1e-63 214.9 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF1304 PF06993.12 ORX96852.1 - 0.22 11.5 2.0 0.4 10.7 2.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1304) Stealth_CR2 PF11380.8 ORX96855.1 - 6.7e-18 64.8 0.2 3.9e-11 43.1 0.0 2.9 2 0 0 2 2 2 2 Stealth protein CR2, conserved region 2 Stealth_CR1 PF17101.5 ORX96855.1 - 1e-07 31.5 0.0 3.2e-07 29.9 0.0 1.9 1 0 0 1 1 1 1 Stealth protein CR1, conserved region 1 Stealth_CR4 PF17103.5 ORX96855.1 - 2.7e-07 30.4 0.0 1e-06 28.5 0.0 2.0 1 0 0 1 1 1 1 Stealth protein CR4, conserved region 4 Stealth_CR3 PF17102.5 ORX96855.1 - 3.2e-05 23.7 1.1 8.7e-05 22.3 1.1 1.8 1 0 0 1 1 1 1 Stealth protein CR3, conserved region 3 Glyco_transf_34 PF05637.12 ORX96856.1 - 1.2e-10 41.6 0.1 1.4e-07 31.5 0.1 2.2 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Glyco_transf_25 PF01755.17 ORX96857.1 - 9.3e-10 38.7 0.0 1.1e-07 31.9 0.0 2.3 2 0 0 2 2 2 2 Glycosyltransferase family 25 (LPS biosynthesis protein) Glyco_transf_25 PF01755.17 ORX96858.1 - 2.6e-10 40.5 0.0 7.8e-08 32.4 0.1 2.1 2 0 0 2 2 2 2 Glycosyltransferase family 25 (LPS biosynthesis protein) Pkinase PF00069.25 ORX96894.1 - 1.4e-07 31.2 0.1 0.0077 15.6 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORX96894.1 - 5.1e-07 29.2 0.0 0.006 15.9 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Ezh2_MCSS PF18600.1 ORX96894.1 - 0.015 14.9 0.1 0.04 13.5 0.0 1.7 2 0 0 2 2 2 0 MCSS domain Asp PF00026.23 ORX96896.1 - 1.3e-63 215.4 9.4 1.6e-63 215.0 9.4 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 ORX96896.1 - 8.3e-08 32.7 4.3 0.0052 17.0 1.0 3.2 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 ORX96896.1 - 6.9e-07 29.8 2.2 0.006 17.2 1.2 3.3 3 1 0 3 3 3 2 Aspartyl protease gag-asp_proteas PF13975.6 ORX96896.1 - 0.0019 18.7 1.5 2.3 8.8 0.3 3.0 2 1 0 2 2 2 2 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 ORX96896.1 - 0.055 13.2 0.6 0.15 11.9 0.0 2.0 3 0 0 3 3 3 0 Xylanase inhibitor C-terminal VSG_B PF13206.6 ORX96897.1 - 0.93 8.7 5.2 1.3 8.2 5.2 1.1 1 0 0 1 1 1 0 Trypanosomal VSG domain ADH_N PF08240.12 ORX96898.1 - 3.3e-28 97.7 0.7 5.5e-28 97.0 0.7 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORX96898.1 - 9.2e-23 80.6 0.1 1.6e-22 79.8 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ORX96898.1 - 4.7e-05 24.5 0.0 8.3e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 ORX96898.1 - 0.0017 17.8 0.2 0.0029 17.0 0.2 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain adh_short PF00106.25 ORX96898.1 - 0.013 14.9 0.3 0.024 14.1 0.3 1.5 1 0 0 1 1 1 0 short chain dehydrogenase DUF4448 PF14610.6 ORX96900.1 - 0.019 14.7 0.0 0.032 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Hexokinase_1 PF00349.21 ORX96901.1 - 1.7e-52 178.2 0.0 2.6e-52 177.6 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.16 ORX96901.1 - 4.8e-52 176.8 0.0 6.1e-52 176.4 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Mso1_Sec1_bdg PF14475.6 ORX96901.1 - 0.11 12.1 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 Sec1-binding region of Mso1 GILT PF03227.16 ORX96902.1 - 9.2e-21 74.1 0.2 1.6e-20 73.3 0.2 1.4 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) DUF1681 PF07933.14 ORX96903.1 - 6.1e-56 188.2 0.0 1.1e-55 187.4 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1681) HAD PF12710.7 ORX96904.1 - 3.8e-23 82.9 0.0 5.6e-23 82.3 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 ORX96904.1 - 0.00011 21.7 0.0 0.11 11.8 0.0 2.1 2 0 0 2 2 2 2 Putative Phosphatase UMPH-1 PF05822.12 ORX96904.1 - 0.0026 17.3 0.1 0.021 14.4 0.0 2.2 2 1 1 3 3 3 1 Pyrimidine 5'-nucleotidase (UMPH-1) DUF2357 PF09823.9 ORX96904.1 - 0.13 11.5 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2357) She9_MDM33 PF05546.11 ORX96905.1 - 5.5e-57 192.8 8.3 7.7e-57 192.3 8.3 1.2 1 0 0 1 1 1 1 She9 / Mdm33 family Exonuc_VII_L PF02601.15 ORX96905.1 - 0.018 14.6 2.4 0.032 13.8 2.4 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF966 PF06136.13 ORX96905.1 - 0.029 14.1 0.7 0.044 13.5 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Nup54 PF13874.6 ORX96905.1 - 0.13 12.4 7.0 0.26 11.4 7.0 1.5 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 YscO-like PF16789.5 ORX96905.1 - 1.4 8.9 21.6 0.44 10.6 3.6 2.6 2 1 1 3 3 3 0 YscO-like protein Aldedh PF00171.22 ORX96907.1 - 1.7e-130 435.7 0.0 1.9e-130 435.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 ORX96907.1 - 0.00032 19.9 0.1 0.0016 17.6 0.1 2.0 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) CdiI_2 PF18593.1 ORX96907.1 - 0.086 13.5 0.1 0.22 12.2 0.1 1.7 1 0 0 1 1 1 0 CdiI immunity protein Fungal_trans PF04082.18 ORX96909.1 - 2.3e-30 105.5 0.0 6.4e-30 104.1 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORX96909.1 - 1.5e-08 34.6 8.6 2.3e-08 34.0 8.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 ORX96909.1 - 0.11 11.3 0.0 0.19 10.5 0.0 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain dsrm PF00035.26 ORX96909.1 - 0.3 11.8 1.8 0.66 10.7 1.8 1.6 1 0 0 1 1 1 0 Double-stranded RNA binding motif Bunya_NS-S PF01104.17 ORX96911.1 - 0.0021 17.8 0.0 0.14 12.0 0.0 2.2 2 0 0 2 2 2 2 Bunyavirus non-structural protein NS-s PQ-loop PF04193.14 ORX96912.1 - 8.4e-19 67.1 10.0 5.9e-11 42.0 1.4 4.0 4 1 0 4 4 4 3 PQ loop repeat DUF4153 PF13687.6 ORX96912.1 - 0.0011 18.6 4.1 0.0011 18.6 4.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4153) MatE PF01554.18 ORX96913.1 - 1.1e-24 86.9 12.9 2e-24 86.1 12.9 1.4 1 0 0 1 1 1 1 MatE Crp PF00325.20 ORX96913.1 - 0.03 14.0 0.7 5.7 6.7 0.0 2.7 2 0 0 2 2 2 0 Bacterial regulatory proteins, crp family 60KD_IMP PF02096.20 ORX96953.1 - 1.4e-23 83.7 0.1 1.9e-23 83.2 0.1 1.2 1 0 0 1 1 1 1 60Kd inner membrane protein Thg1C PF14413.6 ORX96953.1 - 0.32 11.2 1.6 0.72 10.0 0.8 1.9 2 1 0 2 2 2 0 Thg1 C terminal domain PLU-1 PF08429.11 ORX96954.1 - 2e-104 349.4 16.7 3.3e-102 342.1 15.5 2.2 2 0 0 2 2 2 2 PLU-1-like protein JmjC PF02373.22 ORX96954.1 - 3.7e-45 153.0 0.2 9.9e-45 151.6 0.2 1.8 1 0 0 1 1 1 1 JmjC domain, hydroxylase ARID PF01388.21 ORX96954.1 - 3.9e-22 78.7 0.1 1.2e-21 77.2 0.1 1.9 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain PHD PF00628.29 ORX96954.1 - 2.2e-18 65.9 26.4 4.2e-11 42.6 4.8 3.0 3 0 0 3 3 3 2 PHD-finger JmjN PF02375.17 ORX96954.1 - 1.2e-16 60.3 1.2 3e-16 59.1 1.2 1.8 1 0 0 1 1 1 1 jmjN domain zf-C5HC2 PF02928.16 ORX96954.1 - 1.6e-15 57.2 2.3 4.9e-15 55.7 2.3 1.8 1 0 0 1 1 1 1 C5HC2 zinc finger zf-PHD-like PF15446.6 ORX96954.1 - 0.16 11.6 8.8 0.84 9.2 0.4 3.0 3 0 0 3 3 3 0 PHD/FYVE-zinc-finger like domain zf-H2C2_2 PF13465.6 ORX96954.1 - 1.5 9.4 5.1 18 6.0 0.3 4.2 3 0 0 3 3 3 0 Zinc-finger double domain C1_1 PF00130.22 ORX96954.1 - 3.3 7.7 12.1 0.71 9.8 3.0 3.4 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-HC5HC2H PF13771.6 ORX96954.1 - 3.8 7.8 14.5 0.13 12.5 2.1 3.3 3 0 0 3 3 3 0 PHD-like zinc-binding domain zf-RanBP PF00641.18 ORX96954.1 - 6.8 6.1 8.9 4.4 6.7 0.6 2.8 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others GIY-YIG PF01541.24 ORX96955.1 - 1.7e-19 69.8 0.0 3.3e-19 68.9 0.0 1.4 1 0 0 1 1 1 1 GIY-YIG catalytic domain FANCL_C PF11793.8 ORX96955.1 - 8.4e-05 22.7 0.8 8.4e-05 22.7 0.8 1.7 2 0 0 2 2 2 1 FANCL C-terminal domain PHD PF00628.29 ORX96955.1 - 0.002 18.0 1.5 0.0041 17.0 1.5 1.6 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H_2 PF13832.6 ORX96955.1 - 0.011 15.8 0.5 0.022 14.9 0.5 1.4 1 0 0 1 1 1 0 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 ORX96955.1 - 0.026 14.8 0.8 0.06 13.6 0.8 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-RING_2 PF13639.6 ORX96955.1 - 0.083 13.2 3.1 0.16 12.4 3.1 1.5 1 0 0 1 1 1 0 Ring finger domain A2L_zn_ribbon PF08792.10 ORX96955.1 - 0.31 10.8 1.5 0.46 10.2 0.2 1.9 2 0 0 2 2 2 0 A2L zinc ribbon domain Thymidylate_kin PF02223.17 ORX96956.1 - 8.1e-46 156.0 0.0 9.4e-46 155.8 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase NTPase_1 PF03266.15 ORX96956.1 - 0.0023 17.8 0.1 1.6 8.6 0.2 2.2 2 0 0 2 2 2 2 NTPase CPT PF07931.12 ORX96956.1 - 0.01 15.7 0.0 0.026 14.4 0.0 1.6 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein MipZ PF09140.11 ORX96956.1 - 0.014 14.7 0.1 1.3 8.2 0.0 2.1 2 0 0 2 2 2 0 ATPase MipZ AAA_33 PF13671.6 ORX96956.1 - 0.015 15.4 0.0 0.05 13.8 0.0 1.8 1 1 1 2 2 2 0 AAA domain His_Phos_1 PF00300.22 ORX96956.1 - 0.033 13.9 0.1 0.056 13.1 0.1 1.3 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) AAA_18 PF13238.6 ORX96956.1 - 0.054 14.0 0.0 0.11 13.0 0.0 1.7 1 1 1 2 2 2 0 AAA domain KTI12 PF08433.10 ORX96956.1 - 0.057 12.9 0.1 0.16 11.4 0.0 1.8 2 1 0 2 2 2 0 Chromatin associated protein KTI12 PPK2 PF03976.14 ORX96956.1 - 0.062 12.8 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Polyphosphate kinase 2 (PPK2) RE_BstXI PF09552.10 ORX96956.1 - 0.15 11.2 0.2 0.37 9.9 0.1 1.6 2 0 0 2 2 2 0 BstXI restriction endonuclease MFS_1 PF07690.16 ORX96958.1 - 8.9e-19 67.6 31.5 5.9e-18 64.9 31.5 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 ORX96958.1 - 3.9e-09 35.5 4.0 3.9e-09 35.5 4.0 2.7 1 1 1 3 3 3 2 Fungal trichothecene efflux pump (TRI12) Zn_clus PF00172.18 ORX96959.1 - 1.4e-15 57.1 28.4 4.2e-08 33.2 9.8 2.6 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ORX96959.1 - 1.2e-06 27.7 0.2 2.2e-06 26.9 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 ORX96960.1 - 2.4e-42 145.2 32.5 2.4e-42 145.2 32.5 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Deltameth_res PF16020.5 ORX96960.1 - 0.032 14.1 3.0 0.26 11.2 0.1 3.0 2 0 0 2 2 2 0 Deltamethrin resistance LIP PF03583.14 ORX96961.1 - 4.8e-49 167.2 0.3 6.7e-49 166.7 0.3 1.2 1 0 0 1 1 1 1 Secretory lipase Glyco_hydro_88 PF07470.13 ORX96962.1 - 1.1e-29 103.6 0.5 1.3e-29 103.4 0.5 1.1 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 CcmH PF03918.14 ORX96965.1 - 0.084 12.2 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Cytochrome C biogenesis protein NMO PF03060.15 ORX96966.1 - 2e-56 191.8 0.6 2.7e-55 188.1 0.6 1.9 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 ORX96966.1 - 5.2e-14 52.0 0.0 1.4e-12 47.3 0.0 2.2 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 ORX96966.1 - 0.00092 18.3 0.6 0.0018 17.4 0.6 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase DUF1902 PF08972.11 ORX96966.1 - 0.025 14.5 0.0 0.07 13.1 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1902) PBP PF01161.20 ORX96968.1 - 1.8e-18 67.1 0.0 2.4e-18 66.7 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Epiglycanin_TR PF05647.11 ORX96969.1 - 0.14 12.0 5.1 0.26 11.2 5.1 1.5 1 0 0 1 1 1 0 Tandem-repeating region of mucin, epiglycanin-like DNA_pol_A_exo1 PF01612.20 ORX96970.1 - 6.4e-06 26.0 0.0 7.5e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 3'-5' exonuclease HRDC PF00570.23 ORX96971.1 - 1.3e-21 76.3 0.0 2.8e-16 59.3 0.0 2.5 2 0 0 2 2 2 2 HRDC domain HHH PF00633.23 ORX96971.1 - 0.051 13.5 0.3 6.9 6.7 0.1 2.5 2 0 0 2 2 2 0 Helix-hairpin-helix motif Opi1 PF08618.10 ORX96972.1 - 6.2e-37 127.8 14.8 1.2e-24 87.4 11.1 3.1 1 1 1 2 2 2 2 Transcription factor Opi1 Baculo_PEP_C PF04513.12 ORX96972.1 - 0.017 15.2 0.9 0.029 14.4 0.9 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Peptidase_S64 PF08192.11 ORX96972.1 - 0.45 8.9 1.6 0.6 8.5 1.6 1.1 1 0 0 1 1 1 0 Peptidase family S64 AAA PF00004.29 ORX96973.1 - 7.3e-17 62.0 0.0 6e-16 59.1 0.0 2.4 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 ORX96973.1 - 4.6e-05 23.7 0.7 0.001 19.4 0.4 3.1 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 ORX96973.1 - 0.00012 22.5 0.1 0.00072 20.0 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 ORX96973.1 - 0.0014 18.6 0.0 0.005 16.8 0.0 2.0 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Torsin PF06309.11 ORX96973.1 - 0.02 15.0 0.0 0.043 13.9 0.0 1.5 1 0 0 1 1 1 0 Torsin AAA_30 PF13604.6 ORX96973.1 - 0.033 13.9 0.0 0.079 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 ORX96973.1 - 0.044 13.9 0.0 0.11 12.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF4736 PF15883.5 ORX96973.1 - 0.06 13.1 0.1 0.15 11.8 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4736) IstB_IS21 PF01695.17 ORX96973.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein ABC2_membrane PF01061.24 ORX96976.1 - 2.2e-80 269.0 55.3 2.9e-40 137.9 27.7 2.4 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 ORX96976.1 - 2e-35 122.3 0.0 1.9e-16 60.8 0.0 2.7 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.12 ORX96976.1 - 1.6e-27 95.2 7.1 1e-23 83.0 0.0 3.4 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.6 ORX96976.1 - 1.6e-16 60.7 0.2 1.6e-16 60.7 0.2 2.2 2 0 0 2 2 1 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 ORX96976.1 - 8.8e-11 41.5 4.5 8.8e-11 41.5 4.5 3.1 2 1 1 3 3 3 2 ABC-2 family transporter protein AAA_16 PF13191.6 ORX96976.1 - 4.3e-06 27.2 0.0 0.0038 17.6 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 ORX96976.1 - 1.4e-05 25.1 0.0 0.23 11.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 ORX96976.1 - 3.1e-05 24.5 0.4 0.029 14.9 0.0 3.2 4 0 0 4 4 2 1 AAA domain AAA_29 PF13555.6 ORX96976.1 - 0.00019 21.1 0.4 0.014 15.1 0.1 2.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_25 PF13481.6 ORX96976.1 - 0.00086 18.9 0.2 0.02 14.5 0.1 2.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 ORX96976.1 - 0.00097 19.3 0.1 0.76 9.9 0.0 3.2 3 0 0 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 ORX96976.1 - 0.0011 19.0 0.1 0.0046 16.9 0.0 2.0 2 0 0 2 2 2 1 RsgA GTPase SMC_N PF02463.19 ORX96976.1 - 0.018 14.5 0.0 1.1 8.6 0.0 2.8 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 ORX96976.1 - 0.021 15.1 0.0 0.43 10.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 ORX96976.1 - 0.022 15.0 0.1 0.25 11.6 0.1 2.5 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 ORX96976.1 - 0.024 14.6 0.7 3.3 7.6 0.1 2.4 2 0 0 2 2 2 0 NACHT domain AAA_30 PF13604.6 ORX96976.1 - 0.027 14.2 0.1 2 8.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 ORX96976.1 - 0.036 13.8 0.4 9.9 5.9 0.1 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.19 ORX96976.1 - 0.072 12.7 1.3 0.67 9.5 0.2 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.6 ORX96976.1 - 0.11 12.9 0.1 16 5.8 0.0 2.7 3 0 0 3 3 2 0 AAA domain AAA_17 PF13207.6 ORX96976.1 - 0.12 12.8 2.7 7 7.1 0.0 2.9 3 0 0 3 3 2 0 AAA domain AAA_23 PF13476.6 ORX96976.1 - 0.45 11.0 0.0 0.45 11.0 0.0 3.0 3 0 0 3 3 3 0 AAA domain FAM180 PF15173.6 ORX97003.1 - 0.033 14.2 0.8 0.11 12.5 0.1 2.2 3 1 1 4 4 4 0 FAM180 family MerR-DNA-bind PF09278.11 ORX97003.1 - 1 9.9 4.7 5.6 7.6 0.8 3.5 3 1 0 3 3 3 0 MerR, DNA binding Seryl_tRNA_N PF02403.22 ORX97003.1 - 3 8.1 6.7 3.7 7.8 4.9 2.1 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain AMP-binding PF00501.28 ORX97008.1 - 6.6e-68 229.2 0.0 1e-67 228.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORX97008.1 - 1.8e-09 38.4 0.0 3.5e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Nodulin_late PF07127.11 ORX97009.1 - 0.025 14.9 12.7 0.65 10.4 0.4 3.2 3 0 0 3 3 3 0 Late nodulin protein Gamma-thionin PF00304.20 ORX97009.1 - 0.053 13.8 33.3 0.6 10.4 4.0 3.3 3 0 0 3 3 3 0 Gamma-thionin family DUF5500 PF17604.2 ORX97009.1 - 0.064 13.4 0.0 2.2 8.4 0.0 2.7 3 0 0 3 3 3 0 Family of unknown function (DUF5500) FMO-like PF00743.19 ORX97011.1 - 4.1e-10 38.7 1.1 7.3e-09 34.6 1.1 2.3 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 ORX97011.1 - 0.0018 17.5 0.0 0.0061 15.7 0.0 1.7 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 ORX97011.1 - 0.0033 17.6 0.0 0.014 15.6 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 ORX97011.1 - 0.024 13.9 0.0 0.18 11.0 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 ORX97011.1 - 0.11 11.7 0.0 0.71 9.1 0.0 1.9 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase 3Beta_HSD PF01073.19 ORX97012.1 - 2.6e-41 141.5 0.0 3.8e-41 140.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 ORX97012.1 - 3.9e-19 69.1 0.0 5.7e-19 68.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ORX97012.1 - 1.8e-12 47.3 0.1 1.1e-11 44.8 0.0 2.1 3 0 0 3 3 3 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 ORX97012.1 - 7.9e-10 38.3 0.0 6.4e-08 32.1 0.0 2.3 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 ORX97012.1 - 2.1e-07 31.0 0.0 3.2e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 ORX97012.1 - 1.5e-06 27.5 0.0 4.7e-06 25.9 0.0 1.7 2 0 0 2 2 2 1 RmlD substrate binding domain NmrA PF05368.13 ORX97012.1 - 0.0001 21.9 0.0 0.00017 21.3 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family KR PF08659.10 ORX97012.1 - 0.003 17.5 0.0 0.0083 16.1 0.0 1.7 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 ORX97012.1 - 0.02 14.1 0.0 0.045 12.9 0.0 1.6 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein Semialdhyde_dh PF01118.24 ORX97012.1 - 0.062 13.7 0.1 2 8.9 0.0 2.3 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Sbt_1 PF05982.12 ORX97013.1 - 0.0011 18.3 0.1 0.0011 18.2 0.1 1.0 1 0 0 1 1 1 1 Na+-dependent bicarbonate transporter superfamily DUF1485 PF07364.12 ORX97014.1 - 1.3e-105 352.8 0.7 1.7e-105 352.5 0.1 1.3 2 0 0 2 2 2 1 Metallopeptidase family M81 MlrC_C PF07171.12 ORX97014.1 - 3e-57 193.7 0.1 4.5e-57 193.1 0.1 1.3 1 0 0 1 1 1 1 MlrC C-terminus Sugar_tr PF00083.24 ORX97015.1 - 2.3e-68 231.1 16.2 2.7e-68 230.9 16.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORX97015.1 - 1.2e-26 93.5 21.1 1.2e-26 93.5 21.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Tetraspanin PF00335.20 ORX97016.1 - 0.11 12.2 0.0 0.11 12.2 0.0 1.9 2 0 0 2 2 2 0 Tetraspanin family Cation_ATPase_C PF00689.21 ORX97019.1 - 3.1e-45 154.1 2.7 3.1e-45 154.1 2.7 2.4 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 ORX97019.1 - 2e-35 121.9 1.6 2e-35 121.9 1.6 2.5 4 0 0 4 4 4 1 E1-E2 ATPase Cation_ATPase PF13246.6 ORX97019.1 - 1.6e-21 76.1 0.0 3.5e-21 75.1 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 ORX97019.1 - 5.2e-19 69.4 0.6 1.3e-18 68.1 0.6 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 ORX97019.1 - 9.7e-13 47.6 0.2 3.4e-11 42.6 0.0 2.7 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 ORX97019.1 - 9.6e-05 22.2 0.4 0.0027 17.5 0.3 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase LptF_LptG PF03739.14 ORX97019.1 - 0.46 9.3 7.0 0.099 11.5 3.1 1.9 2 0 0 2 2 2 0 Lipopolysaccharide export system permease LptF/LptG Acetyltransf_2 PF00797.17 ORX97020.1 - 1e-36 126.9 0.0 2e-36 126.0 0.0 1.5 1 1 0 1 1 1 1 N-acetyltransferase HET PF06985.11 ORX97021.1 - 6e-22 78.6 0.1 7.5e-22 78.3 0.1 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PAP2 PF01569.21 ORX97022.1 - 1.5e-10 41.0 0.6 2.9e-10 40.1 0.6 1.4 1 0 0 1 1 1 1 PAP2 superfamily CHAT PF12770.7 ORX97025.1 - 3.6e-32 111.9 0.0 4.4e-32 111.7 0.0 1.0 1 0 0 1 1 1 1 CHAT domain DHOR PF06537.11 ORX97025.1 - 0.024 13.3 0.1 0.031 12.9 0.1 1.1 1 0 0 1 1 1 0 Di-haem oxidoreductase, putative peroxidase Xylo_C PF12529.8 ORX97025.1 - 0.028 14.0 0.0 0.041 13.5 0.0 1.2 1 0 0 1 1 1 0 Xylosyltransferase C terminal Peptidase_C25 PF01364.18 ORX97025.1 - 0.058 12.6 0.0 0.063 12.5 0.0 1.1 1 0 0 1 1 1 0 Peptidase family C25 HIP1_clath_bdg PF16515.5 ORX97026.1 - 0.0035 17.9 6.3 0.0035 17.9 6.3 3.9 2 2 1 4 4 4 1 Clathrin-binding domain of Huntingtin-interacting protein 1 HALZ PF02183.18 ORX97026.1 - 0.012 15.8 4.1 26 5.1 0.1 4.4 4 0 0 4 4 4 0 Homeobox associated leucine zipper 3HCDH_N PF02737.18 ORX97026.1 - 0.048 13.5 5.4 0.06 13.2 4.7 1.5 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain KASH_CCD PF14662.6 ORX97026.1 - 0.27 11.1 20.5 0.2 11.5 9.0 2.5 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH DUF4472 PF14739.6 ORX97026.1 - 1.8 9.3 16.1 0.13 13.0 6.5 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4472) Tup_N PF08581.10 ORX97026.1 - 6.1 7.2 13.7 0.54 10.6 0.7 4.0 3 1 1 4 4 4 0 Tup N-terminal ATG16 PF08614.11 ORX97027.1 - 1.7e-05 25.2 13.1 0.0091 16.2 1.4 2.2 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) CASP_C PF08172.12 ORX97027.1 - 0.00017 21.0 2.0 0.00017 21.0 2.0 2.2 2 0 0 2 2 2 1 CASP C terminal ABC_tran_CTD PF16326.5 ORX97027.1 - 0.00052 20.2 13.4 0.001 19.3 1.1 3.7 2 1 1 4 4 4 1 ABC transporter C-terminal domain ADIP PF11559.8 ORX97027.1 - 0.0051 16.9 13.1 0.058 13.5 0.8 2.4 1 1 1 2 2 2 2 Afadin- and alpha -actinin-Binding DUF4407 PF14362.6 ORX97027.1 - 0.0053 16.2 9.8 0.26 10.6 3.5 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF4407) TMF_TATA_bd PF12325.8 ORX97027.1 - 0.0066 16.7 10.6 0.4 10.9 0.3 3.2 1 1 1 3 3 3 1 TATA element modulatory factor 1 TATA binding Lebercilin PF15619.6 ORX97027.1 - 0.012 15.3 14.5 0.029 14.0 14.3 1.7 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease KASH_CCD PF14662.6 ORX97027.1 - 0.015 15.1 14.4 0.091 12.6 4.6 2.7 1 1 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH HIP1_clath_bdg PF16515.5 ORX97027.1 - 0.022 15.3 9.7 0.5 11.0 2.2 2.6 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Filament PF00038.21 ORX97027.1 - 0.029 14.0 12.7 0.048 13.2 8.7 2.1 1 1 1 2 2 2 0 Intermediate filament protein Ubiquitin_3 PF14836.6 ORX97027.1 - 0.036 14.1 1.0 0.56 10.2 0.1 2.4 1 1 0 2 2 2 0 Ubiquitin-like domain DUF724 PF05266.14 ORX97027.1 - 0.058 13.2 10.9 0.052 13.4 1.3 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF724) OmpH PF03938.14 ORX97027.1 - 0.071 13.5 12.3 0.86 9.9 6.2 2.3 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) SF3b1 PF08920.10 ORX97027.1 - 0.089 13.3 0.6 1.7 9.2 0.0 2.7 3 0 0 3 3 3 0 Splicing factor 3B subunit 1 DUF3450 PF11932.8 ORX97027.1 - 0.12 11.7 12.2 0.16 11.2 0.8 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) E2F_CC-MB PF16421.5 ORX97027.1 - 0.19 12.1 5.0 1.7 9.1 0.6 2.6 1 1 1 2 2 2 0 E2F transcription factor CC-MB domain CdvA PF18822.1 ORX97027.1 - 0.33 10.8 12.1 0.59 10.0 1.2 3.6 1 1 2 3 3 3 0 CdvA-like coiled-coil domain APG6_N PF17675.1 ORX97027.1 - 0.46 11.0 13.5 1.6e+02 2.8 10.8 2.9 1 1 0 1 1 1 0 Apg6 coiled-coil region Prominin PF05478.11 ORX97027.1 - 0.56 8.1 6.1 1 7.3 5.5 1.6 1 1 1 2 2 2 0 Prominin BLOC1_2 PF10046.9 ORX97027.1 - 0.56 10.5 7.0 0.62 10.4 0.9 2.9 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 JIP_LZII PF16471.5 ORX97027.1 - 0.89 9.8 4.6 24 5.2 0.0 3.9 4 1 0 4 4 4 0 JNK-interacting protein leucine zipper II CtIP_N PF10482.9 ORX97027.1 - 0.95 9.5 9.3 0.57 10.2 5.1 2.7 1 1 1 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain SHE3 PF17078.5 ORX97027.1 - 0.99 9.1 16.4 2.2 7.9 16.4 1.6 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 Snf7 PF03357.21 ORX97027.1 - 1 8.9 13.2 2 8.0 0.0 2.9 2 1 1 3 3 3 0 Snf7 Atg14 PF10186.9 ORX97027.1 - 1.5 7.8 14.7 11 5.0 13.7 2.0 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF1664 PF07889.12 ORX97027.1 - 1.6 8.7 6.0 6.6 6.8 0.3 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Cep57_CLD_2 PF14197.6 ORX97027.1 - 1.7 8.8 6.1 16 5.6 0.6 3.1 2 1 0 2 2 2 0 Centrosome localisation domain of PPC89 DUF16 PF01519.16 ORX97027.1 - 2 9.0 8.5 3.1 8.3 3.3 3.0 1 1 1 2 2 2 0 Protein of unknown function DUF16 CENP-H PF05837.12 ORX97027.1 - 2.3 8.7 14.9 4.8 7.6 5.4 2.7 1 1 3 4 4 4 0 Centromere protein H (CENP-H) TPR_MLP1_2 PF07926.12 ORX97027.1 - 2.3 8.3 12.6 3.1 7.9 8.4 2.7 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF4200 PF13863.6 ORX97027.1 - 2.4 8.6 15.4 0.25 11.8 2.0 3.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4200) Exonuc_VII_L PF02601.15 ORX97027.1 - 2.5 7.6 8.6 4.5 6.8 8.7 1.4 1 1 0 1 1 1 0 Exonuclease VII, large subunit PI3K_P85_iSH2 PF16454.5 ORX97027.1 - 3.7 7.1 14.1 0.29 10.7 5.9 2.8 2 1 2 4 4 3 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain 60KD_IMP PF02096.20 ORX97027.1 - 3.8 7.4 0.0 3.8 7.4 0.0 2.6 3 0 0 3 3 3 0 60Kd inner membrane protein TMPIT PF07851.13 ORX97027.1 - 4.4 6.4 11.1 2.3 7.4 3.2 2.3 1 1 1 2 2 2 0 TMPIT-like protein TMCO5 PF14992.6 ORX97027.1 - 5.5 6.5 12.7 1.6 8.2 9.9 1.5 2 0 0 2 2 1 0 TMCO5 family CEP209_CC5 PF16574.5 ORX97027.1 - 6 7.1 12.4 2.5 8.3 7.0 2.4 1 1 2 3 3 3 0 Coiled-coil region of centrosome protein CE290 SlyX PF04102.12 ORX97027.1 - 7.2 7.3 9.8 12 6.6 0.7 3.9 2 1 2 4 4 4 0 SlyX ADH_zinc_N PF00107.26 ORX97045.1 - 0.00055 19.9 0.0 0.00081 19.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase MFS_1 PF07690.16 ORX97047.1 - 7.9e-39 133.6 59.4 7.9e-39 133.6 59.4 3.0 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 ORX97047.1 - 4.1e-16 58.5 26.0 7.8e-16 57.6 26.0 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 ORX97047.1 - 7.6e-11 41.5 29.6 4.4e-10 39.0 15.9 2.5 2 0 0 2 2 2 2 Sugar (and other) transporter Ysc84 PF04366.12 ORX97047.1 - 0.49 10.2 2.7 0.41 10.4 0.2 2.1 2 0 0 2 2 2 0 Las17-binding protein actin regulator RPA43_OB PF17875.1 ORX97049.1 - 4.7e-13 49.8 0.3 4.7e-13 49.8 0.3 2.6 2 1 0 2 2 2 1 RPA43 OB domain in RNA Pol I SHS2_Rpb7-N PF03876.17 ORX97049.1 - 3.3e-05 24.2 0.0 5.8e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Brix PF04427.18 ORX97050.1 - 6.2e-29 101.5 0.0 7.6e-29 101.2 0.0 1.1 1 0 0 1 1 1 1 Brix domain adh_short_C2 PF13561.6 ORX97052.1 - 3.1e-66 223.3 0.0 3.9e-66 223.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORX97052.1 - 1.1e-52 178.3 0.2 1.4e-52 178.0 0.2 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORX97052.1 - 2.5e-16 60.1 0.1 3.4e-16 59.7 0.1 1.1 1 0 0 1 1 1 1 KR domain ADH_zinc_N PF00107.26 ORX97052.1 - 0.17 11.9 1.0 1.5 8.8 1.0 2.2 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Phage_holin_3_6 PF07332.11 ORX97056.1 - 0.11 12.5 0.5 0.19 11.8 0.5 1.4 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Pheromone PF08015.11 ORX97057.1 - 1.6 9.8 6.5 6 8.0 3.0 3.1 3 0 0 3 3 3 0 Fungal mating-type pheromone IU_nuc_hydro PF01156.19 ORX97058.1 - 5.1e-51 174.0 0.0 1.7e-50 172.4 0.0 1.8 1 1 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase SURF4 PF02077.15 ORX97059.1 - 3.2e-94 315.5 5.8 3.7e-94 315.3 5.8 1.0 1 0 0 1 1 1 1 SURF4 family NMN_transporter PF04973.12 ORX97059.1 - 0.022 14.8 9.8 0.042 13.8 9.8 1.5 1 0 0 1 1 1 0 Nicotinamide mononucleotide transporter DUF1405 PF07187.11 ORX97059.1 - 0.084 12.9 6.5 0.034 14.1 3.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1405) UPF0139 PF03669.13 ORX97059.1 - 0.69 9.8 4.5 0.64 9.9 0.9 2.5 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0139) DoxX PF07681.12 ORX97059.1 - 1.3 9.6 19.0 2.9 8.6 0.1 3.7 3 2 1 4 4 4 0 DoxX PorA PF11271.8 ORX97062.1 - 0.099 11.9 9.4 0.0096 15.2 5.0 1.5 2 0 0 2 2 2 0 Porin PorA SNF5 PF04855.12 ORX97063.1 - 2.2e-84 283.0 0.0 2.9e-84 282.6 0.0 1.1 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 GATA PF00320.27 ORX97063.1 - 0.0042 16.7 4.3 0.012 15.3 4.3 1.8 1 1 0 1 1 1 1 GATA zinc finger CBM_19 PF03427.13 ORX97065.1 - 0.00061 19.7 8.4 0.0011 18.9 6.5 2.5 1 1 1 2 2 2 1 Carbohydrate binding domain (family 19) Glyco_hydro_61 PF03443.14 ORX97065.1 - 0.019 14.9 1.6 0.021 14.8 0.1 2.0 2 1 0 2 2 2 0 Glycosyl hydrolase family 61 Peptidase_C97 PF05903.14 ORX97066.1 - 0.092 12.6 0.4 0.32 10.8 0.3 1.9 1 1 1 2 2 2 0 PPPDE putative peptidase domain Piwi PF02171.17 ORX97093.1 - 3.2e-84 282.7 0.0 4.3e-84 282.3 0.0 1.1 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 ORX97093.1 - 4.5e-18 66.2 0.0 1.6e-17 64.4 0.0 2.0 2 0 0 2 2 2 1 N-terminal domain of argonaute ArgoL1 PF08699.10 ORX97093.1 - 9.5e-15 54.0 0.1 2.4e-14 52.7 0.1 1.7 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoL2 PF16488.5 ORX97093.1 - 1.9e-09 37.7 0.0 5.5e-09 36.2 0.0 1.9 1 0 0 1 1 1 1 Argonaute linker 2 domain PAZ PF02170.22 ORX97093.1 - 5.7e-05 22.9 0.0 0.00017 21.4 0.0 1.7 1 0 0 1 1 1 1 PAZ domain Ribosomal_S7 PF00177.21 ORX97097.1 - 3.4e-28 98.2 0.0 6.2e-28 97.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Usp PF00582.26 ORX97098.1 - 3.8e-22 79.3 0.5 6.6e-15 55.8 0.1 2.6 2 0 0 2 2 2 2 Universal stress protein family TetR_C_28 PF17937.1 ORX97098.1 - 0.094 13.2 0.0 0.25 11.8 0.0 1.7 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain HET PF06985.11 ORX97099.1 - 2.4e-17 63.6 0.0 4.8e-17 62.7 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Cellulase PF00150.18 ORX97100.1 - 1.9e-49 168.6 0.2 2.6e-49 168.2 0.2 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Acetyltransf_1 PF00583.25 ORX97101.1 - 5.3e-12 46.0 0.0 7.9e-12 45.4 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ORX97101.1 - 8e-11 42.2 0.0 1.6e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ORX97101.1 - 2.9e-08 33.5 0.0 2.3e-07 30.7 0.0 2.1 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_10 PF13673.7 ORX97101.1 - 3.4e-08 33.5 0.0 7.2e-08 32.4 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 ORX97101.1 - 3.4e-05 23.5 0.0 6e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 GNAT acetyltransferase Acetyltransf_9 PF13527.7 ORX97101.1 - 3.9e-05 23.7 0.0 0.00013 22.0 0.0 1.9 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 ORX97101.1 - 0.0048 17.0 0.0 0.0098 16.0 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.7 ORX97101.1 - 0.091 13.4 0.0 0.38 11.4 0.0 2.0 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Patatin PF01734.22 ORX97103.1 - 3.6e-11 43.6 0.0 7.3e-11 42.6 0.0 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase ABC_tran PF00005.27 ORX97103.1 - 0.00096 19.7 0.0 0.0024 18.4 0.0 1.6 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 ORX97103.1 - 0.0089 15.9 0.0 0.018 15.0 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase Zeta_toxin PF06414.12 ORX97103.1 - 0.022 14.0 0.0 0.054 12.8 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_22 PF13401.6 ORX97103.1 - 0.09 13.1 0.0 0.29 11.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.17 ORX97103.1 - 0.094 12.8 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_16 PF13191.6 ORX97103.1 - 0.11 12.9 0.1 0.67 10.3 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain MMR_HSR1 PF01926.23 ORX97103.1 - 0.2 11.7 0.0 0.43 10.7 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_29 PF13555.6 ORX97103.1 - 0.22 11.3 0.1 0.54 10.0 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 ORX97103.1 - 0.23 12.0 0.1 0.67 10.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain Glyco_hydro_43 PF04616.14 ORX97104.1 - 6.1e-32 111.1 2.6 3.6e-31 108.5 2.6 2.2 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_68 PF02435.16 ORX97104.1 - 0.0034 16.3 0.1 0.38 9.6 0.0 2.8 3 1 0 3 3 3 2 Levansucrase/Invertase ArlS_N PF18719.1 ORX97104.1 - 0.15 12.3 0.0 0.26 11.5 0.0 1.4 1 0 0 1 1 1 0 ArlS sensor domain WYL PF13280.6 ORX97104.1 - 0.17 11.9 0.0 3 7.9 0.0 2.4 2 1 0 3 3 3 0 WYL domain Oxysterol_BP PF01237.18 ORX97106.1 - 1.1e-112 376.6 0.0 2.4e-112 375.5 0.0 1.6 1 1 0 1 1 1 1 Oxysterol-binding protein PH_8 PF15409.6 ORX97106.1 - 1.1e-38 131.3 1.6 1.3e-38 131.2 0.2 1.8 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 ORX97106.1 - 2.2e-07 31.4 0.2 7.2e-07 29.7 0.0 2.0 2 0 0 2 2 2 1 PH domain Plus-3 PF03126.18 ORX97107.1 - 1.3e-22 80.4 0.0 5.8e-22 78.3 0.0 2.0 2 0 0 2 2 2 1 Plus-3 domain COQ7 PF03232.13 ORX97108.1 - 2.4e-70 235.8 0.1 2.9e-70 235.5 0.1 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.17 ORX97108.1 - 0.0067 16.8 0.0 0.012 16.0 0.0 1.3 1 0 0 1 1 1 1 Rubrerythrin MRC1 PF09444.10 ORX97109.1 - 1.8e-36 125.9 20.0 1.8e-36 125.9 20.0 9.0 6 4 4 10 10 10 1 MRC1-like domain Mut7-C PF01927.16 ORX97110.1 - 0.017 15.2 2.3 0.017 15.2 2.3 2.0 1 1 1 2 2 2 0 Mut7-C RNAse domain zf-MIZ PF02891.20 ORX97110.1 - 2 8.2 6.3 9.7 6.0 0.3 3.6 3 0 0 3 3 3 0 MIZ/SP-RING zinc finger LIM PF00412.22 ORX97110.1 - 2.6 8.3 8.9 8.5 6.7 8.7 2.1 1 1 0 1 1 1 0 LIM domain zf-C2H2_2 PF12756.7 ORX97110.1 - 3.6 8.0 8.2 3.4 8.1 0.0 3.4 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 ORX97110.1 - 5 8.2 16.2 1.9 9.6 0.9 3.9 3 0 0 3 3 3 0 C2H2-type zinc finger zf-Di19 PF05605.12 ORX97110.1 - 7.1 7.0 11.2 5.3 7.4 5.3 2.9 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding MOSC PF03473.17 ORX97111.1 - 2e-28 99.0 0.0 2.8e-28 98.6 0.0 1.2 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 ORX97111.1 - 7.8e-18 64.5 0.0 1.2e-17 63.8 0.0 1.3 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain FAD_binding_4 PF01565.23 ORX97112.1 - 3.4e-22 78.7 0.7 1.2e-21 76.9 0.4 1.9 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 ORX97112.1 - 0.00013 22.0 0.2 0.00024 21.1 0.2 1.5 1 0 0 1 1 1 1 Berberine and berberine like ADH_zinc_N PF00107.26 ORX97113.1 - 6e-08 32.7 0.2 1.8e-07 31.2 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ORX97113.1 - 1.5e-05 24.8 0.0 9.2e-05 22.3 0.0 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Mor PF08765.11 ORX97113.1 - 0.11 12.5 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Mor transcription activator family Pkinase_fungal PF17667.1 ORX97137.1 - 1.6e-32 112.8 1.6 2.9e-16 59.2 3.2 2.6 1 1 1 2 2 2 2 Fungal protein kinase DUF3727 PF12527.8 ORX97139.1 - 0.078 13.2 0.3 0.14 12.4 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3727) RINT1_TIP1 PF04437.13 ORX97139.1 - 0.13 11.1 0.0 0.16 10.8 0.0 1.0 1 0 0 1 1 1 0 RINT-1 / TIP-1 family Pkinase PF00069.25 ORX97141.1 - 3.1e-19 69.4 0.0 4.6e-19 68.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX97141.1 - 1.5e-18 67.1 0.0 1.5e-17 63.7 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 ORX97141.1 - 0.00011 21.6 0.6 0.00018 20.9 0.6 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 ORX97141.1 - 0.0088 15.4 0.2 0.28 10.5 0.2 2.0 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 ORX97141.1 - 0.08 12.9 0.5 0.2 11.6 0.4 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 ORX97141.1 - 0.12 12.0 0.1 0.18 11.3 0.1 1.3 1 0 0 1 1 1 0 RIO1 family Seadorna_VP7 PF07387.11 ORX97141.1 - 0.14 11.2 0.1 0.2 10.7 0.1 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 PMG PF05287.12 ORX97142.1 - 0.031 14.3 0.0 0.19 11.8 0.0 1.9 1 1 0 1 1 1 0 PMG protein GETHR PF05671.11 ORX97142.1 - 1.3 8.4 14.9 14 5.2 1.5 5.0 1 1 4 5 5 5 0 GETHR pentapeptide repeat (5 copies) CBP_BcsF PF11120.8 ORX97142.1 - 9.4 6.4 27.5 5.2 7.3 3.8 4.7 1 1 3 4 4 4 0 Cellulose biosynthesis protein BcsF Ank_2 PF12796.7 ORX97166.1 - 7e-23 81.0 4.1 4.2e-15 56.1 1.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 ORX97166.1 - 4.6e-16 58.5 2.1 1.8e-07 31.3 0.2 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 ORX97166.1 - 5.3e-16 58.8 0.1 2.7e-15 56.5 0.1 2.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORX97166.1 - 2.9e-14 51.8 0.3 6.2e-06 26.2 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 ORX97166.1 - 2.8e-12 46.6 4.6 3.8e-07 30.3 0.1 2.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) FliS_cochap PF16522.5 ORX97166.1 - 0.15 12.0 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 Flagellar FLiS export co-chaperone, HP1076 WW PF00397.26 ORX97167.1 - 2.6e-09 37.0 3.0 5.8e-09 35.9 3.0 1.6 1 0 0 1 1 1 1 WW domain WRW PF10206.9 ORX97167.1 - 0.054 13.9 0.3 0.12 12.7 0.3 1.5 1 0 0 1 1 1 0 Mitochondrial F1F0-ATP synthase, subunit f Fungal_trans PF04082.18 ORX97169.1 - 7.3e-13 48.2 0.1 2e-12 46.7 0.0 1.9 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORX97169.1 - 2.4e-05 24.4 10.7 4.4e-05 23.5 10.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gtr1_RagA PF04670.12 ORX97170.1 - 1.8e-92 308.9 0.0 2.4e-92 308.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 ORX97170.1 - 4.4e-08 33.4 0.0 8e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 ORX97170.1 - 9.3e-08 31.8 0.0 1.5e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Ras family Arf PF00025.21 ORX97170.1 - 1.5e-07 31.0 0.0 3e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 ORX97170.1 - 8.8e-07 29.0 0.0 1.9e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 ORX97170.1 - 0.0017 17.9 0.0 0.0044 16.6 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 ORX97170.1 - 0.0021 18.0 0.1 0.14 12.0 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase DUF815 PF05673.13 ORX97170.1 - 0.0026 16.9 0.1 0.0042 16.3 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) G-alpha PF00503.20 ORX97170.1 - 0.025 13.7 2.7 2.5 7.2 0.0 2.8 2 1 1 3 3 3 0 G-protein alpha subunit ABC_tran PF00005.27 ORX97170.1 - 0.03 14.8 0.1 0.059 13.9 0.1 1.6 1 1 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 ORX97170.1 - 0.063 13.0 0.1 0.17 11.6 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 ORX97170.1 - 0.14 11.7 0.1 0.47 9.9 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region AIG1 PF04548.16 ORX97170.1 - 0.17 11.2 0.2 1.2 8.4 0.1 2.2 2 0 0 2 2 2 0 AIG1 family DUF1688 PF07958.11 ORX97171.1 - 3.9e-182 605.6 0.0 4.5e-182 605.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) TPR_1 PF00515.28 ORX97172.1 - 8.6e-06 25.4 0.5 1.2 9.1 0.2 3.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 ORX97172.1 - 3.2e-05 23.7 2.7 0.49 10.6 0.5 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat DnaJ PF00226.31 ORX97172.1 - 0.037 14.2 0.1 0.1 12.7 0.1 1.7 1 0 0 1 1 1 0 DnaJ domain PQ-loop PF04193.14 ORX97173.1 - 3.5e-39 132.4 16.9 1.3e-20 72.9 2.4 2.8 3 0 0 3 3 3 2 PQ loop repeat DUF962 PF06127.11 ORX97174.1 - 1.1e-22 80.0 0.0 1.7e-22 79.3 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF962) Sugar_tr PF00083.24 ORX97175.1 - 3.2e-91 306.5 17.4 4e-91 306.2 17.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORX97175.1 - 3e-13 49.4 34.9 6e-11 41.9 31.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily UAA PF08449.11 ORX97175.1 - 0.0054 16.0 0.2 0.012 14.8 0.2 1.5 1 0 0 1 1 1 1 UAA transporter family SPC22 PF04573.12 ORX97176.1 - 2e-38 131.6 0.2 1.4e-36 125.5 0.2 2.1 1 1 0 1 1 1 1 Signal peptidase subunit Imm_superinfect PF14373.6 ORX97176.1 - 0.27 11.2 2.0 0.63 10.0 2.0 1.6 1 0 0 1 1 1 0 Superinfection immunity protein HET PF06985.11 ORX97177.1 - 4e-27 95.3 0.0 1.2e-26 93.8 0.0 1.9 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) CMV_1a PF12467.8 ORX97177.1 - 0.0012 19.3 0.0 0.0025 18.2 0.0 1.5 1 0 0 1 1 1 1 Cucumber mosaic virus 1a protein family UIM PF02809.20 ORX97177.1 - 0.14 12.2 4.8 0.43 10.6 4.8 1.9 1 0 0 1 1 1 0 Ubiquitin interaction motif Glyco_hydro_61 PF03443.14 ORX97179.1 - 0.009 16.0 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_19 PF03427.13 ORX97179.1 - 4.9 7.2 13.2 3.7 7.6 8.5 3.4 2 1 0 2 2 2 0 Carbohydrate binding domain (family 19) Metallophos PF00149.28 ORX97180.1 - 5.9e-37 128.2 0.1 1.2e-36 127.2 0.1 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase MPP6 PF10175.9 ORX97182.1 - 3.7e-07 30.7 10.9 0.0029 18.1 2.1 2.1 2 0 0 2 2 2 2 M-phase phosphoprotein 6 zf-CCHC PF00098.23 ORX97182.1 - 1.1e-06 28.5 2.5 1.8e-06 27.8 2.5 1.4 1 0 0 1 1 1 1 Zinc knuckle Cwf_Cwc_15 PF04889.12 ORX97182.1 - 4.7e-05 23.2 6.0 5.9e-05 22.9 6.0 1.1 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein zf-CCHC_4 PF14392.6 ORX97182.1 - 0.018 14.8 1.1 0.039 13.7 1.1 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_3 PF13917.6 ORX97182.1 - 0.25 11.4 0.2 0.25 11.4 0.2 1.7 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_2 PF13696.6 ORX97182.1 - 0.82 9.5 2.6 1.3 8.9 2.6 1.3 1 0 0 1 1 1 0 Zinc knuckle EthD PF07110.11 ORX97183.1 - 1.9e-18 67.4 0.2 2.4e-18 67.1 0.2 1.1 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 ORX97183.1 - 2.1e-06 28.1 0.3 3.4e-06 27.5 0.3 1.3 1 1 0 1 1 1 1 Methylmuconolactone methyl-isomerase Benyvirus_P25 PF05744.11 ORX97183.1 - 0.052 12.9 0.1 0.064 12.5 0.1 1.1 1 0 0 1 1 1 0 Benyvirus P25/P26 protein Peptidase_M16_M PF16187.5 ORX97184.1 - 2.9e-92 308.9 1.1 7.2e-92 307.6 1.1 1.7 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16_C PF05193.21 ORX97184.1 - 2.3e-36 125.5 0.0 1e-22 81.1 0.0 3.0 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 ORX97184.1 - 3.8e-27 95.1 9.3 1.1e-12 48.2 0.0 4.1 3 2 1 4 4 4 2 Insulinase (Peptidase family M16) HBD PF18534.1 ORX97184.1 - 0.66 10.1 3.4 10 6.3 0.2 3.6 4 0 0 4 4 4 0 Helical bundle domain UPF0029 PF01205.19 ORX97185.1 - 1.6e-34 118.3 0.0 2.5e-34 117.7 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.22 ORX97185.1 - 4.7e-07 30.1 0.0 1.7e-06 28.3 0.0 1.9 1 1 0 1 1 1 1 RWD domain DUF2247 PF10004.9 ORX97225.1 - 0.011 15.6 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2247) GIT1_C PF12205.8 ORX97225.1 - 0.099 12.8 0.1 0.33 11.1 0.0 1.8 2 0 0 2 2 2 0 G protein-coupled receptor kinase-interacting protein 1 C term PilZ_2 PF16823.5 ORX97229.1 - 0.00052 20.2 0.5 0.00079 19.6 0.5 1.2 1 0 0 1 1 1 1 Atypical PilZ domain, cyclic di-GMP receptor mCpol PF18182.1 ORX97230.1 - 0.087 13.2 0.8 0.36 11.2 0.8 1.9 1 1 0 1 1 1 0 minimal CRISPR polymerase domain V_ATPase_I PF01496.19 ORX97230.1 - 0.11 10.4 2.5 0.12 10.2 2.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Striatin PF08232.12 ORX97230.1 - 0.53 10.9 8.6 0.7 10.5 8.6 1.1 1 0 0 1 1 1 0 Striatin family F-box PF00646.33 ORX97234.1 - 1.4e-05 24.8 0.0 2.8e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 ORX97234.1 - 2.5e-05 24.1 1.4 7.7e-05 22.5 0.3 2.1 2 0 0 2 2 2 1 F-box-like Ish1 PF10281.9 ORX97236.1 - 2.8e-56 187.5 20.2 9.5e-15 54.6 0.1 5.3 5 0 0 5 5 5 5 Putative stress-responsive nuclear envelope protein SAP PF02037.27 ORX97236.1 - 6.4e-06 25.8 0.0 0.57 10.0 0.0 3.6 3 0 0 3 3 3 2 SAP domain HeH PF12949.7 ORX97236.1 - 0.00046 19.8 0.0 3.8 7.3 0.0 4.0 4 0 0 4 4 4 1 HeH/LEM domain Slx4 PF09494.10 ORX97236.1 - 0.00071 19.5 1.1 6.8 6.7 0.0 3.8 5 0 0 5 5 5 2 Slx4 endonuclease PG_binding_1 PF01471.18 ORX97236.1 - 0.12 12.6 0.4 5.7 7.2 0.1 3.3 3 1 0 3 3 3 0 Putative peptidoglycan binding domain Lsr2 PF11774.8 ORX97236.1 - 0.56 10.4 5.9 0.55 10.4 0.2 3.0 3 1 0 3 3 3 0 Lsr2 CytochromB561_N PF09786.9 ORX97237.1 - 5.4 5.9 7.3 5.9 5.8 7.3 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal IBR PF01485.21 ORX97238.1 - 2.8e-12 46.7 40.7 3.5e-07 30.3 11.3 3.3 3 0 0 3 3 3 3 IBR domain, a half RING-finger domain DUF2158 PF09926.9 ORX97238.1 - 0.0017 18.0 0.1 0.0035 17.0 0.1 1.4 1 0 0 1 1 1 1 Uncharacterized small protein (DUF2158) Cation_efflux PF01545.21 ORX97239.1 - 2.7e-09 37.1 8.8 3.6e-09 36.7 8.8 1.1 1 0 0 1 1 1 1 Cation efflux family PIG-Y PF15159.6 ORX97240.1 - 1e-22 80.8 8.1 1.9e-22 79.9 8.1 1.5 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y DUF1218 PF06749.12 ORX97240.1 - 0.012 16.1 2.7 1.6 9.3 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) DUF2956 PF11169.8 ORX97240.1 - 1.9 8.8 5.4 0.96 9.7 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) Cyclin_N PF00134.23 ORX97242.1 - 0.0003 20.5 0.0 0.024 14.4 0.0 2.2 2 0 0 2 2 2 2 Cyclin, N-terminal domain ADD_ATRX PF17981.1 ORX97243.1 - 0.21 11.5 1.8 43 4.1 0.0 3.5 3 0 0 3 3 3 0 Cysteine Rich ADD domain adh_short PF00106.25 ORX97244.1 - 5.8e-20 71.6 0.0 1.8e-15 56.9 0.0 2.4 3 0 0 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.6 ORX97244.1 - 4.1e-14 52.7 0.0 4.8e-13 49.2 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORX97244.1 - 0.032 14.2 0.0 0.057 13.3 0.0 1.4 1 0 0 1 1 1 0 KR domain Apc15p PF05841.11 ORX97245.1 - 0.031 15.1 2.5 0.081 13.7 2.5 1.7 1 1 0 1 1 1 0 Apc15p protein DAO PF01266.24 ORX97246.1 - 4.8e-12 46.1 3.1 4.3e-11 43.0 0.0 2.1 1 1 1 2 2 2 1 FAD dependent oxidoreductase MFS_1 PF07690.16 ORX97247.1 - 0.001 18.1 11.2 0.0012 17.9 11.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily HET PF06985.11 ORX97248.1 - 5.5e-32 111.1 2.1 1.1e-31 110.2 2.1 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) 3HCDH_N PF02737.18 ORX97249.1 - 8.6e-53 178.9 0.4 1.1e-52 178.5 0.4 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 ORX97249.1 - 7.5e-34 116.2 0.0 1.4e-33 115.3 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Sacchrp_dh_NADP PF03435.18 ORX97249.1 - 0.00062 20.0 0.1 0.0011 19.2 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_2 PF03446.15 ORX97249.1 - 0.001 19.3 0.2 0.0027 17.9 0.1 1.7 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase UDPG_MGDP_dh_N PF03721.14 ORX97249.1 - 0.0034 17.0 0.0 0.008 15.8 0.0 1.6 1 1 1 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.16 ORX97249.1 - 0.0062 16.2 0.2 0.029 14.0 0.0 1.9 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.19 ORX97249.1 - 0.013 14.9 0.2 0.043 13.2 0.1 1.9 1 1 2 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 ORX97249.1 - 0.087 12.8 0.0 0.15 12.0 0.0 1.5 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DAO PF01266.24 ORX97249.1 - 0.095 12.3 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase TIMELESS PF04821.14 ORX97250.1 - 2.4e-79 266.5 0.1 6.2e-79 265.1 0.1 1.7 1 0 0 1 1 1 1 Timeless protein TIMELESS_C PF05029.13 ORX97250.1 - 4e-25 89.0 27.9 1.2e-22 80.8 27.9 3.5 1 1 0 1 1 1 1 Timeless protein C terminal region zf-RING_2 PF13639.6 ORX97280.1 - 1.1e-06 28.8 7.2 1.1e-06 28.8 7.2 1.7 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 ORX97280.1 - 0.00025 20.9 6.8 0.00047 20.0 6.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORX97280.1 - 0.00034 20.6 3.8 0.00071 19.5 3.8 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 ORX97280.1 - 0.0054 16.7 5.6 0.0097 15.9 5.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 ORX97280.1 - 0.0055 17.0 4.5 0.013 15.8 4.5 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 ORX97280.1 - 0.069 13.2 4.3 0.066 13.3 2.4 1.9 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 ORX97280.1 - 0.097 12.4 2.1 0.33 10.7 2.1 1.8 1 0 0 1 1 1 0 RING-like zinc finger zf-C3HC4_2 PF13923.6 ORX97280.1 - 0.64 9.9 7.3 1.3 8.9 7.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 ORX97280.1 - 0.82 9.6 8.3 1.7 8.5 8.3 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Tyrosinase PF00264.20 ORX97281.1 - 1.2e-45 156.6 1.4 2.6e-45 155.4 1.4 1.6 1 0 0 1 1 1 1 Common central domain of tyrosinase Tyosinase_C PF18132.1 ORX97281.1 - 4.3e-20 72.6 0.0 1.4e-19 70.9 0.0 1.9 1 1 0 1 1 1 1 Tyosinase C-terminal domain TPP_enzyme_N PF02776.18 ORX97283.1 - 4e-31 107.9 0.0 6.4e-31 107.3 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 ORX97283.1 - 8.6e-22 77.4 0.0 1.4e-21 76.7 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 ORX97283.1 - 2e-12 47.2 0.0 3.8e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain ANTH PF07651.16 ORX97283.1 - 0.25 10.3 0.0 1.7 7.6 0.0 1.9 2 0 0 2 2 2 0 ANTH domain Pkinase PF00069.25 ORX97284.1 - 1.4e-64 218.0 0.0 2e-64 217.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX97284.1 - 1.1e-46 159.2 0.0 1.8e-46 158.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORX97284.1 - 4.6e-10 39.3 0.0 9.7e-07 28.4 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 ORX97284.1 - 0.014 14.7 0.0 0.027 13.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 ORX97284.1 - 0.034 12.9 0.0 0.065 12.0 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase HET PF06985.11 ORX97285.1 - 4.6e-12 46.5 4.0 3e-10 40.6 0.1 2.2 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) AAA_14 PF13173.6 ORX97285.1 - 0.13 12.3 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain Egh16-like PF11327.8 ORX97286.1 - 1.6e-47 162.3 11.6 2.6e-47 161.6 11.6 1.3 1 0 0 1 1 1 1 Egh16-like virulence factor DUF4149 PF13664.6 ORX97287.1 - 0.054 13.8 6.1 0.089 13.1 3.3 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4149) Phage_holin_7_1 PF16081.5 ORX97287.1 - 0.098 12.8 0.8 0.15 12.3 0.6 1.4 1 1 0 1 1 1 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family MRAP PF15183.6 ORX97287.1 - 0.23 11.4 1.2 1.2 9.1 0.1 2.3 1 1 1 2 2 2 0 Melanocortin-2 receptor accessory protein family Vpu PF00558.19 ORX97287.1 - 0.39 10.5 7.2 0.79 9.5 0.0 3.1 3 1 1 4 4 4 0 Vpu protein SPX PF03105.19 ORX97288.1 - 2e-49 169.6 0.4 3.7e-49 168.7 0.4 1.4 1 1 0 1 1 1 1 SPX domain zf-C3HC4_4 PF15227.6 ORX97288.1 - 4.8e-08 33.0 9.5 6.4e-08 32.6 8.4 1.8 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 ORX97288.1 - 3.6e-07 29.9 9.3 6.5e-07 29.1 9.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORX97288.1 - 4e-06 26.8 7.0 9.2e-06 25.6 7.0 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 ORX97288.1 - 2.2e-05 24.7 11.3 4.6e-05 23.7 11.3 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 ORX97288.1 - 5.6e-05 22.9 9.6 5.6e-05 22.9 9.6 1.7 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 ORX97288.1 - 5.8e-05 22.8 11.2 5.8e-05 22.8 11.2 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORX97288.1 - 0.00026 20.9 11.7 0.0049 16.8 12.6 2.3 1 1 1 2 2 2 1 zinc-RING finger domain TerY_C PF15616.6 ORX97288.1 - 0.0013 18.8 0.7 0.0024 18.0 0.7 1.4 1 0 0 1 1 1 1 TerY-C metal binding domain Prok-RING_4 PF14447.6 ORX97288.1 - 0.0016 18.2 9.3 0.012 15.4 9.4 2.1 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 Cep57_MT_bd PF06657.13 ORX97288.1 - 0.024 15.1 0.4 5.4 7.5 0.1 2.7 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 zf-RING_4 PF14570.6 ORX97288.1 - 0.031 14.1 10.3 0.21 11.4 10.2 2.2 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain XLF PF09302.11 ORX97288.1 - 0.075 13.2 0.0 0.25 11.5 0.0 2.0 2 0 0 2 2 2 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component zf-RING_6 PF14835.6 ORX97288.1 - 0.24 11.3 2.6 0.51 10.2 2.6 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 ORX97288.1 - 1.2 9.5 11.5 5.9 7.3 11.6 2.0 1 1 1 2 2 2 0 RING-H2 zinc finger domain DnaJ PF00226.31 ORX97289.1 - 1e-23 83.2 0.6 1e-23 83.2 0.6 2.5 2 0 0 2 2 2 1 DnaJ domain zf-C2H2_jaz PF12171.8 ORX97289.1 - 2.4e-10 40.4 6.1 2.4e-10 40.4 6.1 2.6 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ORX97289.1 - 7e-09 35.8 7.3 1.7e-08 34.6 2.4 2.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 ORX97289.1 - 4.6e-08 33.3 7.7 0.001 19.4 2.3 2.5 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 ORX97289.1 - 0.00092 19.9 7.8 0.21 12.5 0.6 2.8 2 1 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 ORX97289.1 - 0.0013 19.1 6.5 0.1 13.1 0.9 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type RPT PF13446.6 ORX97289.1 - 0.071 13.0 0.1 0.48 10.4 0.0 2.4 3 0 0 3 3 3 0 A repeated domain in UCH-protein zf-C2H2_8 PF15909.5 ORX97289.1 - 0.096 13.0 0.8 0.81 10.0 0.1 2.3 2 0 0 2 2 2 0 C2H2-type zinc ribbon zf-LYAR PF08790.11 ORX97289.1 - 0.098 12.6 2.0 0.18 11.7 0.2 2.3 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-C2H2_6 PF13912.6 ORX97289.1 - 0.57 10.2 3.5 16 5.6 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2HE PF16278.5 ORX97289.1 - 1.1 9.8 5.4 6 7.4 0.4 3.1 3 0 0 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger Lyase_aromatic PF00221.19 ORX97290.1 - 2.7e-155 517.6 0.7 3.5e-155 517.2 0.7 1.1 1 0 0 1 1 1 1 Aromatic amino acid lyase AbiEi_4 PF13338.6 ORX97290.1 - 0.0015 18.6 1.5 0.66 10.2 0.2 2.7 2 0 0 2 2 2 2 Transcriptional regulator, AbiEi antitoxin zf-CCCH_4 PF18044.1 ORX97291.1 - 5.2e-06 26.1 3.5 1.1e-05 25.1 3.5 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger Nucleoporin_FG PF13634.6 ORX97291.1 - 2.7e-05 24.9 126.6 0.25 12.2 41.0 6.3 2 1 5 7 7 7 5 Nucleoporin FG repeat region zf_CCCH_4 PF18345.1 ORX97291.1 - 0.00027 20.9 6.3 0.00048 20.1 6.3 1.4 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 ORX97291.1 - 0.011 15.7 3.2 0.019 14.9 3.2 1.3 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) NupH_GANP PF16768.5 ORX97291.1 - 0.011 15.4 12.1 0.011 15.4 12.1 5.3 1 1 5 6 6 6 0 Nucleoporin homology of Germinal-centre associated nuclear protein Tachystatin_B PF11478.8 ORX97291.1 - 0.1 12.5 1.4 0.25 11.3 1.4 1.6 1 0 0 1 1 1 0 Antimicrobial chitin binding protein tachystatin B Gpi1 PF05024.15 ORX97293.1 - 1.9e-76 256.4 9.0 3e-76 255.7 9.0 1.3 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) CDC45 PF02724.14 ORX97293.1 - 0.0015 16.9 0.8 0.0021 16.4 0.8 1.2 1 0 0 1 1 1 1 CDC45-like protein RNA_pol_Rpc4 PF05132.14 ORX97293.1 - 0.43 11.0 2.2 0.72 10.3 2.2 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 MMR_HSR1 PF01926.23 ORX97294.1 - 1.6e-08 34.6 0.0 3.7e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 ORX97294.1 - 8.7e-07 28.5 0.0 1.5e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 AIG1 family RsgA_GTPase PF03193.16 ORX97294.1 - 0.00071 19.5 0.2 0.00071 19.5 0.2 1.8 2 0 0 2 2 2 1 RsgA GTPase Septin PF00735.18 ORX97294.1 - 0.0014 18.0 0.0 0.16 11.2 0.0 2.4 2 0 0 2 2 2 1 Septin CdvA PF18822.1 ORX97294.1 - 0.021 14.6 1.4 0.12 12.2 1.4 2.0 1 1 0 1 1 1 0 CdvA-like coiled-coil domain ABC_tran PF00005.27 ORX97294.1 - 0.028 15.0 2.6 0.065 13.7 0.0 2.3 2 1 0 2 2 2 0 ABC transporter DUF87 PF01935.17 ORX97294.1 - 0.034 14.3 2.5 0.16 12.0 0.3 2.2 2 0 0 2 2 2 0 Helicase HerA, central domain zf-C4H2 PF10146.9 ORX97294.1 - 0.046 14.0 0.5 0.077 13.3 0.5 1.3 1 0 0 1 1 1 0 Zinc finger-containing protein Dynamin_N PF00350.23 ORX97294.1 - 0.063 13.3 7.5 1.4 9.0 0.3 2.9 2 2 1 3 3 3 0 Dynamin family AAA_33 PF13671.6 ORX97294.1 - 0.071 13.3 0.3 0.18 11.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain SHE3 PF17078.5 ORX97294.1 - 0.1 12.3 7.1 0.16 11.6 7.1 1.2 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 IIGP PF05049.13 ORX97294.1 - 0.11 11.5 0.2 0.32 10.0 0.0 1.7 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) AAA_24 PF13479.6 ORX97294.1 - 0.17 11.6 0.0 0.34 10.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.10 ORX97294.1 - 0.18 11.3 1.3 0.2 11.1 0.0 1.7 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit V-ATPase_G_2 PF16999.5 ORX97294.1 - 0.45 11.0 4.0 0.52 10.8 0.1 2.2 2 0 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit AAA_23 PF13476.6 ORX97294.1 - 0.58 10.6 5.2 4.5 7.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 ORX97295.1 - 1.6e-09 37.9 1.4 3.1e-09 36.9 0.0 2.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase AIG1 PF04548.16 ORX97295.1 - 1.1e-06 28.1 6.1 2e-06 27.3 0.0 2.3 2 0 0 2 2 2 1 AIG1 family SRPRB PF09439.10 ORX97295.1 - 1.7e-05 24.4 0.0 1.7e-05 24.4 0.0 2.7 3 0 0 3 3 3 1 Signal recognition particle receptor beta subunit Septin PF00735.18 ORX97295.1 - 0.00045 19.6 0.0 0.0012 18.2 0.0 1.8 1 0 0 1 1 1 1 Septin AAA_22 PF13401.6 ORX97295.1 - 0.0033 17.7 3.9 0.0072 16.6 0.1 3.0 1 1 1 2 2 2 1 AAA domain Spore_IV_A PF09547.10 ORX97295.1 - 0.005 15.8 0.0 0.013 14.5 0.0 1.6 1 0 0 1 1 1 1 Stage IV sporulation protein A (spore_IV_A) FeoB_N PF02421.18 ORX97295.1 - 0.0061 16.1 0.0 0.013 15.1 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA_18 PF13238.6 ORX97295.1 - 0.0087 16.6 0.0 0.0087 16.6 0.0 3.2 2 1 1 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 ORX97295.1 - 0.0092 15.9 0.3 0.0092 15.9 0.3 1.8 2 0 0 2 2 1 1 RsgA GTPase DUF87 PF01935.17 ORX97295.1 - 0.012 15.7 0.1 0.012 15.7 0.1 2.9 2 1 1 3 3 2 0 Helicase HerA, central domain Viral_helicase1 PF01443.18 ORX97295.1 - 0.014 15.2 0.0 0.032 14.0 0.0 1.6 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Gtr1_RagA PF04670.12 ORX97295.1 - 0.034 13.5 0.0 0.079 12.3 0.0 1.6 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_29 PF13555.6 ORX97295.1 - 0.039 13.7 0.1 0.081 12.7 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Dynamin_N PF00350.23 ORX97295.1 - 0.052 13.6 0.0 0.052 13.6 0.0 4.5 2 2 1 3 3 2 0 Dynamin family AAA_33 PF13671.6 ORX97295.1 - 0.079 13.1 2.1 0.13 12.5 0.0 2.4 2 1 0 2 2 2 0 AAA domain GTP_EFTU PF00009.27 ORX97295.1 - 0.11 12.1 3.6 0.51 9.8 0.2 2.8 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 ORX97295.1 - 0.12 12.1 0.2 0.12 12.1 0.2 2.6 3 1 1 4 4 4 0 Conserved hypothetical ATP binding protein MeaB PF03308.16 ORX97295.1 - 0.13 11.3 8.4 0.13 11.2 0.1 2.6 2 1 1 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB FtsK_SpoIIIE PF01580.18 ORX97295.1 - 0.14 11.5 0.1 0.14 11.5 0.1 2.3 2 1 0 2 2 2 0 FtsK/SpoIIIE family IIGP PF05049.13 ORX97295.1 - 0.17 10.9 0.1 0.17 10.9 0.1 2.4 2 1 0 2 2 2 0 Interferon-inducible GTPase (IIGP) AAA_16 PF13191.6 ORX97295.1 - 0.19 12.1 0.0 0.19 12.1 0.0 2.9 2 1 0 2 2 1 0 AAA ATPase domain Dehydrin PF00257.19 ORX97295.1 - 0.24 11.9 3.5 0.79 10.3 3.5 1.9 1 0 0 1 1 1 0 Dehydrin Arf PF00025.21 ORX97295.1 - 0.32 10.4 4.6 0.74 9.2 0.0 2.7 2 1 1 3 3 3 0 ADP-ribosylation factor family ABC_tran PF00005.27 ORX97295.1 - 0.56 10.7 0.0 0.56 10.7 0.0 2.7 2 1 0 2 2 1 0 ABC transporter G-alpha PF00503.20 ORX97295.1 - 0.86 8.7 8.8 0.19 10.9 0.1 2.8 2 2 1 3 3 3 0 G-protein alpha subunit V_ATPase_I PF01496.19 ORX97295.1 - 0.92 7.3 9.4 1.3 6.9 9.4 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family MMR_HSR1 PF01926.23 ORX97296.1 - 1.6e-11 44.2 0.1 6.6e-10 39.1 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 ORX97296.1 - 1.7e-05 24.9 3.8 0.077 13.1 0.1 3.2 2 1 1 3 3 3 2 Dynamin family RsgA_GTPase PF03193.16 ORX97296.1 - 0.00011 22.2 0.2 0.00011 22.2 0.2 1.9 2 1 0 2 2 2 1 RsgA GTPase ABC_tran PF00005.27 ORX97296.1 - 0.00034 21.1 1.7 0.00087 19.8 0.0 2.2 1 1 1 2 2 2 1 ABC transporter AIG1 PF04548.16 ORX97296.1 - 0.00084 18.7 0.0 0.0018 17.7 0.0 1.5 1 0 0 1 1 1 1 AIG1 family Rab5-bind PF09311.11 ORX97296.1 - 0.0015 18.0 7.1 0.0022 17.5 7.1 1.1 1 0 0 1 1 1 1 Rabaptin-like protein Septin PF00735.18 ORX97296.1 - 0.002 17.5 1.3 0.0024 17.2 0.0 1.8 2 0 0 2 2 2 1 Septin IIGP PF05049.13 ORX97296.1 - 0.0061 15.7 3.0 0.057 12.5 0.1 2.4 3 0 0 3 3 3 1 Interferon-inducible GTPase (IIGP) AAA_18 PF13238.6 ORX97296.1 - 0.007 16.9 0.5 0.14 12.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain FeoB_N PF02421.18 ORX97296.1 - 0.0098 15.4 0.0 0.019 14.5 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA_22 PF13401.6 ORX97296.1 - 0.012 15.9 0.2 0.066 13.5 0.0 2.3 1 1 1 2 2 2 0 AAA domain NB-ARC PF00931.22 ORX97296.1 - 0.019 14.1 0.4 0.043 13.0 0.4 1.6 1 0 0 1 1 1 0 NB-ARC domain ATP_bind_1 PF03029.17 ORX97296.1 - 0.033 14.0 3.7 1.2 8.8 0.7 3.0 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein DUF87 PF01935.17 ORX97296.1 - 0.057 13.5 0.9 0.057 13.5 0.9 2.2 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_33 PF13671.6 ORX97296.1 - 0.069 13.3 0.4 0.3 11.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain ComGG PF14173.6 ORX97296.1 - 0.12 12.8 1.3 0.31 11.5 0.8 1.9 2 0 0 2 2 2 0 ComG operon protein 7 PRK PF00485.18 ORX97296.1 - 0.12 12.1 0.0 0.28 10.9 0.0 1.6 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family ApoO PF09769.9 ORX97296.1 - 0.13 12.3 0.3 0.49 10.4 0.3 2.1 1 1 0 1 1 1 0 Apolipoprotein O AAA_24 PF13479.6 ORX97296.1 - 0.16 11.7 0.6 0.44 10.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF5081 PF16887.5 ORX97296.1 - 0.23 10.5 2.5 0.33 10.0 2.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5081) AAA_23 PF13476.6 ORX97296.1 - 1.8 9.0 11.0 7.3 7.0 0.3 2.3 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 ORX97297.1 - 7.6e-09 35.7 3.6 2e-08 34.3 0.0 2.6 2 1 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 ORX97297.1 - 1.3e-05 25.4 13.6 0.014 15.5 0.0 3.9 2 2 1 3 3 2 2 Dynamin family AIG1 PF04548.16 ORX97297.1 - 0.00013 21.3 0.0 0.00013 21.3 0.0 2.3 2 1 0 2 2 1 1 AIG1 family AAA_18 PF13238.6 ORX97297.1 - 0.00037 21.0 3.1 0.00064 20.3 0.0 2.6 2 1 0 2 2 2 1 AAA domain Septin PF00735.18 ORX97297.1 - 0.00084 18.7 10.0 0.0027 17.0 0.0 2.9 2 2 1 3 3 3 1 Septin AAA_22 PF13401.6 ORX97297.1 - 0.003 17.9 1.5 0.0058 16.9 0.0 2.3 2 1 0 2 2 2 1 AAA domain FeoB_N PF02421.18 ORX97297.1 - 0.0034 16.9 0.0 0.0098 15.4 0.0 1.8 1 0 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 ORX97297.1 - 0.0051 16.7 0.1 0.0051 16.7 0.1 3.0 2 2 0 2 2 1 1 RsgA GTPase Torsin PF06309.11 ORX97297.1 - 0.016 15.3 0.0 0.92 9.6 0.0 2.6 2 0 0 2 2 2 0 Torsin CENP-Q PF13094.6 ORX97297.1 - 0.064 13.5 23.1 0.11 12.7 23.1 1.4 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF87 PF01935.17 ORX97297.1 - 0.072 13.2 0.0 0.072 13.2 0.0 3.0 2 1 0 2 2 1 0 Helicase HerA, central domain SRP54 PF00448.22 ORX97297.1 - 0.079 12.6 3.5 0.11 12.1 0.0 2.8 3 1 0 3 3 3 0 SRP54-type protein, GTPase domain ABC_tran PF00005.27 ORX97297.1 - 0.1 13.1 0.0 0.1 13.1 0.0 2.7 2 1 0 2 2 1 0 ABC transporter Exonuc_VII_L PF02601.15 ORX97297.1 - 0.3 10.6 17.3 0.45 10.0 17.3 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit ATP_bind_1 PF03029.17 ORX97297.1 - 0.65 9.7 0.0 0.65 9.7 0.0 3.1 3 1 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_28 PF13521.6 ORX97297.1 - 1.4 9.2 0.0 1.4 9.2 0.0 3.6 3 1 1 4 4 4 0 AAA domain Atg14 PF10186.9 ORX97297.1 - 5.5 6.0 21.5 8.3 5.4 21.5 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Peptidase_C15 PF01470.17 ORX97298.1 - 1.4e-10 41.7 0.0 9.8e-05 22.6 0.0 2.9 2 1 0 2 2 2 2 Pyroglutamyl peptidase Sec23_trunk PF04811.15 ORX97298.1 - 0.023 14.3 0.0 0.032 13.8 0.0 1.1 1 0 0 1 1 1 0 Sec23/Sec24 trunk domain FAD_binding_3 PF01494.19 ORX97299.1 - 2.9e-14 53.1 0.9 1.9e-11 43.8 0.1 2.5 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.24 ORX97299.1 - 2.2e-05 24.2 0.1 4.9e-05 23.1 0.1 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase SE PF08491.10 ORX97299.1 - 2.4e-05 23.6 0.0 0.00012 21.2 0.0 1.9 1 1 0 1 1 1 1 Squalene epoxidase NAD_binding_8 PF13450.6 ORX97299.1 - 3e-05 24.2 2.1 3.6e-05 23.9 0.6 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ORX97299.1 - 0.001 18.4 0.1 0.0019 17.5 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ORX97299.1 - 0.0047 16.9 0.2 0.098 12.6 0.3 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding CHASE2 PF05226.11 ORX97299.1 - 0.0053 16.5 0.0 0.036 13.8 0.0 2.0 1 1 0 1 1 1 1 CHASE2 domain HI0933_like PF03486.14 ORX97299.1 - 0.027 13.2 0.2 0.041 12.6 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.22 ORX97299.1 - 0.066 12.3 0.3 0.098 11.7 0.3 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Trp_halogenase PF04820.14 ORX97299.1 - 0.074 11.9 0.1 0.26 10.1 0.1 1.8 2 0 0 2 2 2 0 Tryptophan halogenase FAD_binding_2 PF00890.24 ORX97299.1 - 0.1 11.7 1.5 0.15 11.1 1.5 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 ORX97299.1 - 0.15 12.6 0.4 0.49 11.0 0.3 1.9 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase Abhydrolase_1 PF00561.20 ORX97300.1 - 1.5e-14 54.3 0.0 2.6e-14 53.5 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ORX97300.1 - 5.8e-10 38.8 0.0 1.9e-09 37.2 0.0 1.8 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S37 PF05576.11 ORX97300.1 - 0.00068 18.4 0.0 0.0012 17.6 0.0 1.4 1 0 0 1 1 1 1 PS-10 peptidase S37 Esterase PF00756.20 ORX97300.1 - 0.012 15.3 0.0 0.02 14.5 0.0 1.5 1 0 0 1 1 1 0 Putative esterase Peptidase_S9 PF00326.21 ORX97300.1 - 0.014 14.9 0.0 0.067 12.7 0.0 2.0 1 1 0 1 1 1 0 Prolyl oligopeptidase family Kelch_3 PF13415.6 ORX97301.1 - 9.1e-25 86.4 1.8 8.6e-09 35.5 0.0 4.2 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_4 PF13418.6 ORX97301.1 - 5.1e-23 80.8 6.0 5.2e-10 39.2 0.0 3.6 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_5 PF13854.6 ORX97301.1 - 4.5e-20 71.2 3.4 4.2e-09 36.2 0.1 3.6 4 0 0 4 4 4 3 Kelch motif Kelch_6 PF13964.6 ORX97301.1 - 5e-19 67.9 3.7 1.2e-05 25.5 0.1 3.3 2 1 1 3 3 3 3 Kelch motif Kelch_1 PF01344.25 ORX97301.1 - 2e-13 49.7 10.1 5.3e-06 25.9 0.1 4.0 4 1 0 4 4 4 3 Kelch motif Kelch_2 PF07646.15 ORX97301.1 - 9e-08 31.8 6.3 0.011 15.7 0.1 3.9 3 1 0 3 3 3 3 Kelch motif GET2 PF08690.10 ORX97301.1 - 0.4 10.3 3.0 0.48 10.0 3.0 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 AP3D1 PF06375.11 ORX97301.1 - 2.4 8.4 12.0 3.5 7.8 12.0 1.3 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 Ribosomal_S25 PF03297.15 ORX97301.1 - 3.8 7.8 13.5 7.2 6.9 13.5 1.4 1 0 0 1 1 1 0 S25 ribosomal protein TFIIF_alpha PF05793.12 ORX97301.1 - 4.9 5.6 15.1 6.7 5.2 15.1 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) MscS_TM PF12794.7 ORX97301.1 - 9 5.1 5.0 13 4.6 5.0 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 DUF2236 PF09995.9 ORX97340.1 - 4.5e-33 115.3 0.0 6.2e-33 114.9 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) DUF2718 PF10918.8 ORX97340.1 - 0.032 14.7 0.0 0.059 13.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2718) SIMPL PF04402.14 ORX97341.1 - 0.033 14.6 0.1 0.071 13.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF541) Torus PF16131.5 ORX97341.1 - 0.15 12.8 6.4 2.1 9.1 0.3 3.1 3 0 0 3 3 3 0 Torus domain zf-CCCH PF00642.24 ORX97341.1 - 8.7 6.4 12.1 0.12 12.3 2.0 2.7 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) adh_short PF00106.25 ORX97342.1 - 4.2e-28 98.1 0.0 5.6e-28 97.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORX97342.1 - 4.1e-20 72.4 0.0 5.3e-20 72.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORX97342.1 - 1.5e-07 31.5 0.0 2.1e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ORX97342.1 - 0.0017 17.8 0.0 0.0032 17.0 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 ORX97342.1 - 0.0095 15.8 0.0 0.017 15.0 0.0 1.7 1 1 0 1 1 1 1 NAD(P)H-binding Halo_GVPC PF05465.13 ORX97342.1 - 0.12 12.6 0.6 0.3 11.4 0.6 1.7 1 0 0 1 1 1 0 Halobacterial gas vesicle protein C (GVPC) repeat Cytochrom_C PF00034.21 ORX97343.1 - 7.8e-11 43.0 0.0 1.1e-10 42.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 ORX97343.1 - 5.8e-08 32.9 1.3 3.4e-07 30.5 1.3 1.9 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 ORX97343.1 - 0.014 15.1 2.1 0.078 12.7 2.1 2.1 1 1 0 1 1 1 0 Cytochrome c-550 domain Cytochrome-c551 PF10643.9 ORX97343.1 - 0.061 12.9 0.0 0.079 12.5 0.0 1.1 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 BCDHK_Adom3 PF10436.9 ORX97344.1 - 6.8e-75 250.3 0.0 1.1e-74 249.7 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 ORX97344.1 - 6.2e-10 39.6 0.0 1.3e-09 38.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 ORX97344.1 - 0.064 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Rgp1 PF08737.10 ORX97345.1 - 7.6e-145 483.2 0.0 2e-144 481.9 0.0 1.7 2 0 0 2 2 2 1 Rgp1 Arrestin_N PF00339.29 ORX97345.1 - 0.0056 16.7 0.0 0.011 15.8 0.0 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain DUF3584 PF12128.8 ORX97346.1 - 0.0042 14.7 0.0 0.0054 14.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) RNF111_N PF15303.6 ORX97348.1 - 0.027 14.2 0.7 0.048 13.4 0.7 1.3 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase Arkadia N-terminus Methyltransf_3 PF01596.17 ORX97349.1 - 1.8e-33 115.5 0.0 2.3e-33 115.2 0.0 1.0 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 ORX97349.1 - 1.5e-12 48.5 0.0 2.4e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 ORX97349.1 - 7.1e-08 32.5 0.0 1.2e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORX97349.1 - 2.6e-05 24.1 0.0 9.3e-05 22.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 ORX97349.1 - 0.00016 21.3 0.0 0.00029 20.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 ORX97349.1 - 0.00087 19.9 0.0 0.0025 18.5 0.0 1.8 2 1 0 2 2 1 1 Methyltransferase domain TrmK PF04816.12 ORX97349.1 - 0.0017 18.0 0.0 0.0025 17.4 0.0 1.2 1 0 0 1 1 1 1 tRNA (adenine(22)-N(1))-methyltransferase PCMT PF01135.19 ORX97349.1 - 0.0019 18.0 0.0 0.0028 17.4 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.12 ORX97349.1 - 0.038 14.7 0.0 0.085 13.6 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain CMAS PF02353.20 ORX97349.1 - 0.04 13.2 0.0 0.065 12.5 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_15 PF09445.10 ORX97349.1 - 0.054 13.1 0.0 0.077 12.6 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_11 PF08241.12 ORX97349.1 - 0.06 14.0 0.0 0.11 13.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.17 ORX97349.1 - 0.08 12.4 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase UPF0020 PF01170.18 ORX97349.1 - 0.099 12.3 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 GCD14 PF08704.10 ORX97349.1 - 0.12 12.1 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit ICL PF00463.21 ORX97352.1 - 7.8e-196 651.6 0.4 9.1e-196 651.4 0.4 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 ORX97352.1 - 6.7e-09 35.6 0.2 1.4e-08 34.5 0.0 1.6 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase Citrate_synt PF00285.21 ORX97353.1 - 4.1e-98 328.8 0.0 5e-98 328.5 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Glyco_hydro_3_C PF01915.22 ORX97354.1 - 3e-47 161.2 0.0 5.5e-47 160.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 ORX97354.1 - 1.8e-39 136.0 0.0 2.6e-39 135.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 ORX97354.1 - 9.1e-20 70.6 2.0 2e-10 40.6 0.2 2.4 2 0 0 2 2 2 2 Fibronectin type III-like domain ABC_tran PF00005.27 ORX97355.1 - 6.9e-48 162.7 0.1 2.3e-25 89.7 0.0 4.1 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 ORX97355.1 - 6.3e-17 62.3 0.8 0.00018 21.4 0.1 4.3 3 1 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ORX97355.1 - 5e-13 49.0 0.1 0.00087 18.8 0.0 4.3 3 2 1 4 4 4 2 RecF/RecN/SMC N terminal domain Chromo PF00385.24 ORX97355.1 - 3.1e-08 33.4 0.0 6.2e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_23 PF13476.6 ORX97355.1 - 2.1e-07 31.6 0.0 0.029 14.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 ORX97355.1 - 4.9e-07 29.8 0.0 0.0037 17.3 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 ORX97355.1 - 9.7e-07 28.4 0.5 0.012 15.3 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 ORX97355.1 - 8.4e-06 25.8 0.1 0.054 13.4 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase HEAT PF02985.22 ORX97355.1 - 8.9e-06 25.5 0.6 0.32 11.4 0.0 5.7 6 0 0 6 6 5 1 HEAT repeat AAA_28 PF13521.6 ORX97355.1 - 5.7e-05 23.4 0.0 0.027 14.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 ORX97355.1 - 0.00019 21.3 0.2 0.16 11.7 0.4 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 ORX97355.1 - 0.00026 21.3 0.1 0.85 9.9 0.0 3.0 2 1 0 2 2 2 2 AAA domain HEAT_EZ PF13513.6 ORX97355.1 - 0.0003 21.2 6.1 8.3 7.0 0.1 5.0 5 1 0 5 5 4 0 HEAT-like repeat Cnd1 PF12717.7 ORX97355.1 - 0.00074 19.6 0.1 0.22 11.6 0.0 3.0 2 2 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 DUF87 PF01935.17 ORX97355.1 - 0.00093 19.3 0.2 0.19 11.8 0.1 2.7 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_18 PF13238.6 ORX97355.1 - 0.0014 19.2 0.0 0.7 10.4 0.0 2.9 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 ORX97355.1 - 0.0023 17.9 0.0 1.3 9.0 0.0 2.5 2 0 0 2 2 2 1 NACHT domain RNA_helicase PF00910.22 ORX97355.1 - 0.0024 18.2 0.1 3.4 8.1 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_33 PF13671.6 ORX97355.1 - 0.0027 17.9 0.0 1.8 8.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 ORX97355.1 - 0.0049 17.1 0.1 2.3 8.5 0.0 3.2 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit MeaB PF03308.16 ORX97355.1 - 0.0055 15.7 0.3 1.2 8.1 0.0 2.5 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_13 PF13166.6 ORX97355.1 - 0.0068 15.1 0.0 1.6 7.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 ORX97355.1 - 0.0087 15.2 0.5 0.2 10.8 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) CLASP_N PF12348.8 ORX97355.1 - 0.0087 15.6 0.0 0.12 11.9 0.0 2.3 2 0 0 2 2 2 1 CLASP N terminal AAA_30 PF13604.6 ORX97355.1 - 0.021 14.5 0.1 6.9 6.3 0.0 2.8 3 0 0 3 3 2 0 AAA domain PduV-EutP PF10662.9 ORX97355.1 - 0.022 14.5 0.1 0.79 9.5 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.6 ORX97355.1 - 0.028 14.1 0.2 2.6 7.7 0.1 2.6 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 ORX97355.1 - 0.031 14.7 0.0 4.9 7.5 0.0 2.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_27 PF13514.6 ORX97355.1 - 0.033 13.8 0.0 6.4 6.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF3584 PF12128.8 ORX97355.1 - 0.044 11.3 1.1 2.8 5.3 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Roc PF08477.13 ORX97355.1 - 0.055 13.7 0.0 9.6 6.4 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 ORX97355.1 - 0.067 13.3 0.0 1.1 9.3 0.0 2.5 2 1 0 2 2 2 0 Dynamin family Ploopntkinase3 PF18751.1 ORX97355.1 - 0.071 13.0 0.0 12 5.8 0.0 2.4 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 TsaE PF02367.17 ORX97355.1 - 0.11 12.6 0.0 15 5.6 0.0 2.8 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Septin PF00735.18 ORX97355.1 - 0.12 11.6 0.0 6.2 6.0 0.0 2.3 2 0 0 2 2 2 0 Septin Alginate_lyase2 PF08787.11 ORX97355.1 - 0.15 11.9 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 Alginate lyase Zeta_toxin PF06414.12 ORX97355.1 - 0.16 11.2 0.5 6.5 6.0 0.1 2.5 2 0 0 2 2 2 0 Zeta toxin ALF PF03752.13 ORX97355.1 - 0.24 11.4 0.5 2.2 8.3 0.0 2.5 2 0 0 2 2 2 0 Short repeats of unknown function Sugar_tr PF00083.24 ORX97357.1 - 3.3e-80 270.2 19.7 4e-80 269.9 19.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORX97357.1 - 1.3e-21 77.0 29.7 8.8e-17 61.1 2.4 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily UCR_UQCRX_QCR9 PF05365.12 ORX97357.1 - 1.6 8.7 3.9 20 5.2 0.1 3.0 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like RGS PF00615.19 ORX97358.1 - 1.1e-05 25.7 0.0 0.0024 18.1 0.0 2.3 2 0 0 2 2 2 2 Regulator of G protein signaling domain Astacin PF01400.24 ORX97359.1 - 1e-05 25.2 0.0 0.034 13.8 0.0 2.4 2 1 0 2 2 2 2 Astacin (Peptidase family M12A) Astacin PF01400.24 ORX97360.1 - 1.9e-14 53.7 4.3 2.4e-11 43.6 0.5 2.8 2 1 1 3 3 3 2 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.24 ORX97360.1 - 0.0015 18.4 1.4 0.0032 17.3 1.4 1.7 1 1 0 1 1 1 1 Matrixin Reprolysin_3 PF13582.6 ORX97360.1 - 0.0085 16.6 2.7 0.013 16.0 0.6 2.1 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 ORX97360.1 - 0.023 14.8 0.7 0.023 14.8 0.7 1.9 1 1 1 2 2 2 0 Metallo-peptidase family M12 Metallopep PF12044.8 ORX97360.1 - 0.024 13.2 0.1 0.032 12.9 0.1 1.1 1 0 0 1 1 1 0 Putative peptidase family Reprolysin_4 PF13583.6 ORX97360.1 - 0.027 14.1 1.1 0.044 13.4 1.1 1.5 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M43 PF05572.13 ORX97360.1 - 0.063 13.2 0.4 0.11 12.4 0.4 1.4 1 0 0 1 1 1 0 Pregnancy-associated plasma protein-A DUF4157 PF13699.6 ORX97360.1 - 0.21 11.8 2.8 1.8 8.9 2.8 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4157) Glyco_hydro_cc PF11790.8 ORX97361.1 - 9.5e-37 126.8 0.6 7.5e-36 123.9 0.6 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase catalytic core FAD_binding_3 PF01494.19 ORX97385.1 - 4e-22 78.9 0.1 2.5e-11 43.4 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 ORX97385.1 - 1.7e-05 25.0 0.0 3.9e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 ORX97385.1 - 0.0039 16.3 0.0 0.0056 15.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 ORX97385.1 - 0.015 14.5 0.0 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORX97385.1 - 0.021 15.4 0.0 0.053 14.1 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 ORX97385.1 - 0.13 11.3 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein SGL PF08450.12 ORX97386.1 - 9.5e-27 94.1 0.0 1.5e-26 93.5 0.0 1.2 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 ORX97386.1 - 0.0003 20.9 0.0 0.00079 19.6 0.0 1.7 1 0 0 1 1 1 1 Arylesterase Str_synth PF03088.16 ORX97386.1 - 0.0015 18.6 0.0 0.025 14.7 0.0 2.6 1 1 1 2 2 2 1 Strictosidine synthase Cu-oxidase_3 PF07732.15 ORX97387.1 - 9.9e-38 128.8 0.1 5.6e-37 126.4 0.1 2.3 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 ORX97387.1 - 2.2e-37 127.8 3.3 8.3e-36 122.7 0.2 2.8 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.22 ORX97387.1 - 5.4e-29 101.4 0.1 1.4e-28 100.0 0.0 1.7 2 0 0 2 2 2 1 Multicopper oxidase Cytochrom_B561 PF03188.16 ORX97388.1 - 5.3e-11 42.8 9.7 1.1e-10 41.8 9.7 1.5 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 CDH-cyt PF16010.5 ORX97388.1 - 1.3e-08 34.8 0.0 3.2e-08 33.5 0.0 1.7 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase DUF2427 PF10348.9 ORX97388.1 - 2e-08 34.0 0.5 2e-08 34.0 0.5 2.2 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) EMP70 PF02990.16 ORX97388.1 - 0.014 14.0 1.2 0.021 13.5 1.2 1.3 1 0 0 1 1 1 0 Endomembrane protein 70 DUF3290 PF11694.8 ORX97388.1 - 0.031 14.2 3.0 4.4 7.3 0.1 2.7 3 0 0 3 3 2 0 Protein of unknown function (DUF3290) Neurensin PF14927.6 ORX97388.1 - 0.051 13.3 1.2 4.6 7.0 0.1 2.7 1 1 1 2 2 2 0 Neurensin DUF1129 PF06570.11 ORX97388.1 - 0.061 12.8 1.9 6.1 6.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) Phage_holin_2_4 PF16082.5 ORX97388.1 - 0.076 12.8 2.7 3.7 7.4 0.4 2.6 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like MHYT PF03707.16 ORX97388.1 - 0.12 12.5 1.8 11 6.3 0.0 2.9 3 0 0 3 3 2 0 Bacterial signalling protein N terminal repeat DUF2231 PF09990.9 ORX97388.1 - 0.13 12.8 3.3 0.19 12.1 0.4 2.5 1 1 1 2 2 2 0 Predicted membrane protein (DUF2231) FeoB_associated PF12669.7 ORX97388.1 - 0.21 12.0 0.8 1.3 9.5 0.8 2.4 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein DUF1361 PF07099.11 ORX97388.1 - 0.91 9.5 4.7 0.7 9.8 2.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1361) DUF373 PF04123.13 ORX97388.1 - 1.2 8.6 5.1 1.8 8.0 5.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DUF3483 PF11982.8 ORX97388.1 - 1.8 8.2 8.0 0.49 10.0 0.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3483) DUF998 PF06197.13 ORX97388.1 - 2.6 7.6 15.3 0.059 13.0 2.8 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF998) Cation_ATPase_C PF00689.21 ORX97388.1 - 2.7 7.7 5.8 60 3.3 5.8 2.4 1 1 0 1 1 1 0 Cation transporting ATPase, C-terminus DUF3792 PF12670.7 ORX97388.1 - 2.7 8.2 9.0 0.23 11.6 0.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3792) Phage_holin_3_6 PF07332.11 ORX97388.1 - 6.5 6.8 16.4 0.11 12.6 2.1 3.1 2 1 1 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III MerC PF03203.14 ORX97388.1 - 9.1 6.8 10.8 1.7e+03 -0.6 12.2 3.0 1 1 0 1 1 1 0 MerC mercury resistance protein Pkinase PF00069.25 ORX97389.1 - 5.6e-44 150.5 0.1 9.3e-44 149.8 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX97389.1 - 2.3e-28 99.2 0.0 3.8e-28 98.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase TPR_10 PF13374.6 ORX97389.1 - 1.2e-06 28.2 9.6 0.071 13.0 0.1 4.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 ORX97389.1 - 0.0025 18.0 11.2 1.8 8.9 0.1 4.4 3 1 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 ORX97389.1 - 0.0034 18.0 7.2 0.039 14.6 0.8 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat Kdo PF06293.14 ORX97389.1 - 0.023 14.1 2.2 0.052 12.9 0.0 2.1 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 ORX97389.1 - 0.043 13.4 0.3 0.095 12.3 0.3 1.5 1 0 0 1 1 1 0 RIO1 family TPR_1 PF00515.28 ORX97389.1 - 0.056 13.3 4.8 2 8.4 0.2 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 ORX97389.1 - 0.13 13.1 10.7 23 6.1 1.5 4.8 4 1 1 5 5 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 ORX97389.1 - 1.2 9.4 9.8 9.6 6.6 0.8 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat APH PF01636.23 ORX97389.1 - 1.5 8.7 5.8 12 5.7 0.1 3.2 2 1 1 3 3 3 0 Phosphotransferase enzyme family TPR_19 PF14559.6 ORX97389.1 - 5.2 7.6 7.9 20 5.8 0.2 3.8 3 1 1 4 4 4 0 Tetratricopeptide repeat NOA36 PF06524.12 ORX97389.1 - 6 6.1 8.9 12 5.2 8.9 1.4 1 0 0 1 1 1 0 NOA36 protein OTT_1508_deam PF14441.6 ORX97390.1 - 5.1e-20 71.3 0.4 1e-19 70.3 0.4 1.5 1 0 0 1 1 1 1 OTT_1508-like deaminase Aldedh PF00171.22 ORX97392.1 - 2.9e-136 454.7 0.4 3.4e-136 454.4 0.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Voltage_CLC PF00654.20 ORX97394.1 - 1.2e-88 297.8 17.9 2.2e-88 296.9 17.9 1.4 1 0 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.28 ORX97394.1 - 0.0014 19.0 0.0 0.0031 17.9 0.0 1.6 1 0 0 1 1 1 1 CBS domain Phage_holin_2_3 PF16080.5 ORX97394.1 - 3.9 7.3 5.4 4.1 7.2 0.3 2.7 2 0 0 2 2 2 0 Bacteriophage holin family HP1 Glyco_hydro_43 PF04616.14 ORX97395.1 - 1e-26 94.0 1.1 1.2e-26 93.7 1.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 RRM_1 PF00076.22 ORX97396.1 - 1e-14 54.1 0.2 1.4e-14 53.6 0.2 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glyco_hydro_72 PF03198.14 ORX97397.1 - 5.1e-51 173.8 0.0 7.7e-51 173.2 0.0 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 ORX97397.1 - 5.2e-12 46.3 0.9 1.2e-11 45.1 0.9 1.6 1 0 0 1 1 1 1 X8 domain SKG6 PF08693.10 ORX97397.1 - 1.6 8.2 4.8 3 7.3 4.8 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain FANCI_S1-cap PF14674.6 ORX97398.1 - 0.0047 17.0 0.0 0.0064 16.6 0.0 1.2 1 0 0 1 1 1 1 FANCI solenoid 1 cap Zw10 PF06248.13 ORX97399.1 - 0.011 14.3 0.0 0.013 14.1 0.0 1.0 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 6PGD PF00393.19 ORX97400.1 - 2.6e-88 296.2 0.1 3.1e-88 295.9 0.1 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 ORX97400.1 - 3.7e-28 98.7 0.0 6.4e-28 97.9 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 ORX97400.1 - 0.0021 18.3 0.0 0.0046 17.2 0.0 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase FA_desaturase PF00487.24 ORX97401.1 - 0.44 10.3 2.4 0.89 9.3 2.4 1.5 1 0 0 1 1 1 0 Fatty acid desaturase Malic_M PF03949.15 ORX97403.1 - 4.9e-92 307.8 0.0 7.4e-92 307.2 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 ORX97403.1 - 4.4e-67 225.4 0.0 6.4e-67 224.9 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Helicase_IV_N PF12462.8 ORX97403.1 - 0.064 13.2 0.1 0.12 12.3 0.1 1.4 1 0 0 1 1 1 0 DNA helicase IV / RNA helicase N terminal Helo_like_N PF17111.5 ORX97435.1 - 2e-05 24.1 0.2 3e-05 23.5 0.2 1.3 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins YbjQ_1 PF01906.17 ORX97435.1 - 0.019 15.6 0.0 0.12 13.1 0.0 2.2 2 0 0 2 2 2 0 Putative heavy-metal-binding DUF4748 PF15932.5 ORX97436.1 - 1.4e-19 69.6 1.0 1.4e-19 69.6 1.0 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4748) NPCC PF08058.11 ORX97437.1 - 1.9e-26 92.7 0.0 2.7e-26 92.2 0.0 1.2 1 0 0 1 1 1 1 Nuclear pore complex component UL42 PF17638.2 ORX97437.1 - 0.22 11.5 2.9 0.54 10.2 2.9 1.7 1 0 0 1 1 1 0 HCMV UL42 AMP-binding PF00501.28 ORX97438.1 - 7.1e-13 47.9 0.1 7.6e-12 44.5 0.1 2.0 1 1 0 1 1 1 1 AMP-binding enzyme Transp_cyt_pur PF02133.15 ORX97439.1 - 2.5e-99 333.0 45.7 3e-99 332.8 45.7 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin NPP1 PF05630.11 ORX97440.1 - 3e-56 190.7 0.6 3.6e-56 190.4 0.6 1.1 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) Pkinase PF00069.25 ORX97441.1 - 7.1e-39 133.7 0.0 9.1e-39 133.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX97441.1 - 1.2e-24 87.0 0.0 2.1e-23 83.0 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase C2 PF00168.30 ORX97441.1 - 5.8e-08 33.0 0.0 1.4e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 C2 domain Pkinase_fungal PF17667.1 ORX97441.1 - 0.014 14.2 0.0 0.017 13.9 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 ORX97441.1 - 0.028 14.3 0.0 0.057 13.3 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 ORX97441.1 - 0.036 13.4 0.0 0.071 12.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 ORX97441.1 - 0.075 12.6 0.1 0.53 9.9 0.0 2.0 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 ORX97441.1 - 0.1 12.2 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 RIO1 family WD40 PF00400.32 ORX97444.1 - 6.5e-46 153.4 24.9 1.3e-09 38.5 0.2 12.0 12 0 0 12 12 12 9 WD domain, G-beta repeat Utp12 PF04003.12 ORX97444.1 - 1.4e-25 89.7 0.0 2.1e-25 89.1 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 ORX97444.1 - 9.9e-22 77.1 0.0 0.039 14.3 0.0 10.5 5 2 6 11 11 11 8 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 ORX97444.1 - 1.6e-09 37.2 0.1 0.49 9.3 0.0 5.7 3 2 2 5 5 5 4 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 ORX97444.1 - 6.9e-06 25.0 4.3 1.6 7.3 0.0 4.8 3 2 2 5 5 5 3 Nucleoporin Nup120/160 eIF2A PF08662.11 ORX97444.1 - 1.5e-05 24.9 0.6 0.089 12.7 0.0 4.9 4 2 1 5 5 5 2 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.6 ORX97444.1 - 0.00077 18.9 0.3 9.3 5.5 0.0 4.2 3 2 1 4 4 4 2 Neuroblastoma-amplified sequence, N terminal WD40_like PF17005.5 ORX97444.1 - 0.0036 16.7 0.0 1.6 8.0 0.0 3.5 4 0 0 4 4 4 1 WD40-like domain PQQ_3 PF13570.6 ORX97444.1 - 0.011 16.2 4.7 3.2 8.4 0.2 5.1 6 0 0 6 6 6 0 PQQ-like domain PALB2_WD40 PF16756.5 ORX97444.1 - 0.12 11.3 0.0 5.8 5.7 0.0 2.7 3 0 0 3 3 3 0 Partner and localizer of BRCA2 WD40 domain Septin PF00735.18 ORX97445.1 - 3.3e-112 374.4 0.2 4.7e-112 373.9 0.2 1.2 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 ORX97445.1 - 4.5e-07 30.0 0.0 9.2e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ORX97445.1 - 9.1e-06 25.7 0.1 6.4e-05 22.9 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 ORX97445.1 - 2.9e-05 23.7 4.0 0.00012 21.7 0.5 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 ORX97445.1 - 0.001 19.3 0.2 0.0058 16.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain Pox_A32 PF04665.12 ORX97445.1 - 0.0036 16.8 0.1 0.0064 16.0 0.1 1.3 1 0 0 1 1 1 1 Poxvirus A32 protein Roc PF08477.13 ORX97445.1 - 0.0071 16.6 0.1 0.016 15.4 0.1 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase IIGP PF05049.13 ORX97445.1 - 0.011 14.8 0.0 0.021 13.9 0.0 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_24 PF13479.6 ORX97445.1 - 0.011 15.4 0.0 0.02 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AIG1 PF04548.16 ORX97445.1 - 0.012 14.9 0.0 0.024 14.0 0.0 1.5 1 0 0 1 1 1 0 AIG1 family FOXP-CC PF16159.5 ORX97445.1 - 0.017 15.8 1.9 0.057 14.1 1.9 2.0 1 0 0 1 1 1 0 FOXP coiled-coil domain AAA_16 PF13191.6 ORX97445.1 - 0.02 15.3 0.1 0.091 13.1 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.27 ORX97445.1 - 0.038 14.5 1.0 0.11 13.0 0.0 2.1 2 1 0 2 2 2 0 ABC transporter Ras PF00071.22 ORX97445.1 - 0.04 13.5 0.9 0.12 12.0 0.6 2.0 2 1 0 2 2 2 0 Ras family KAP_NTPase PF07693.14 ORX97445.1 - 0.05 12.8 0.0 0.069 12.4 0.0 1.6 1 1 0 1 1 1 0 KAP family P-loop domain T2SSE PF00437.20 ORX97445.1 - 0.053 12.6 0.5 0.16 11.0 0.1 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein NACHT PF05729.12 ORX97445.1 - 0.077 12.9 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Sigma54_activat PF00158.26 ORX97445.1 - 0.095 12.4 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain PduV-EutP PF10662.9 ORX97445.1 - 0.12 12.2 0.4 4.7 7.0 0.4 2.5 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation RNA_helicase PF00910.22 ORX97445.1 - 0.14 12.6 0.0 0.38 11.2 0.0 1.9 1 0 0 1 1 1 0 RNA helicase ATP_bind_1 PF03029.17 ORX97445.1 - 0.2 11.4 0.8 14 5.4 0.2 2.6 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Dynamin_N PF00350.23 ORX97445.1 - 0.3 11.1 6.6 2.6 8.1 0.1 3.2 2 1 1 3 3 3 0 Dynamin family DUF1043 PF06295.12 ORX97445.1 - 1.3 9.1 5.7 0.42 10.6 1.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) DUF1664 PF07889.12 ORX97445.1 - 1.6 8.8 4.3 0.6 10.1 1.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) AAA_11 PF13086.6 ORX97445.1 - 3.1 7.5 6.2 29 4.3 0.1 2.2 2 0 0 2 2 2 0 AAA domain Myc-LZ PF02344.15 ORX97445.1 - 4.6 7.4 7.0 2.8 8.1 1.4 2.5 2 0 0 2 2 2 0 Myc leucine zipper domain Glyco_hydro_61 PF03443.14 ORX97448.1 - 4e-61 206.6 0.0 4.6e-61 206.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CDH-cyt PF16010.5 ORX97449.1 - 7.9e-54 182.1 1.8 1.4e-53 181.3 1.8 1.4 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase GMC_oxred_N PF00732.19 ORX97449.1 - 3.7e-24 85.6 0.1 1.2e-23 83.9 0.1 2.0 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 ORX97449.1 - 5e-20 72.5 0.0 9.3e-20 71.6 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase CBM_1 PF00734.18 ORX97449.1 - 1.2e-12 47.5 11.3 4.1e-12 45.8 11.3 2.0 1 0 0 1 1 1 1 Fungal cellulose binding domain FAD_binding_2 PF00890.24 ORX97449.1 - 4.9e-07 29.2 0.6 0.00045 19.4 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain HI0933_like PF03486.14 ORX97449.1 - 0.00054 18.8 0.1 0.0035 16.1 0.1 2.0 2 0 0 2 2 2 1 HI0933-like protein DOMON PF03351.17 ORX97449.1 - 0.0021 18.3 0.6 0.01 16.0 0.0 2.4 3 0 0 3 3 3 1 DOMON domain Pyr_redox_2 PF07992.14 ORX97449.1 - 0.0022 17.3 0.2 0.011 14.9 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORX97449.1 - 0.0079 16.4 0.0 0.0079 16.4 0.0 2.5 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 ORX97449.1 - 0.074 12.1 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 ORX97449.1 - 0.085 12.1 0.6 0.19 10.9 0.6 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORX97449.1 - 0.12 13.0 0.0 2 9.1 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase WAK_assoc PF14380.6 ORX97450.1 - 0.0024 18.6 1.7 0.0026 18.4 1.7 1.2 1 0 0 1 1 1 1 Wall-associated receptor kinase C-terminal PSI PF01437.25 ORX97450.1 - 0.035 14.6 8.5 0.059 13.9 8.5 1.4 1 0 0 1 1 1 0 Plexin repeat PSI_integrin PF17205.3 ORX97450.1 - 0.16 11.8 4.9 0.28 11.0 4.9 1.4 1 0 0 1 1 1 0 Integrin plexin domain NOB1_Zn_bind PF08772.11 ORX97456.1 - 1.2e-28 99.0 1.1 1.2e-28 99.0 1.1 1.8 2 0 0 2 2 2 1 Nin one binding (NOB1) Zn-ribbon like PIN_6 PF17146.4 ORX97456.1 - 8.9e-28 96.6 0.2 8.9e-28 96.6 0.2 2.4 3 0 0 3 3 3 1 PIN domain of ribonuclease zf-NADH-PPase PF09297.11 ORX97456.1 - 0.0013 18.3 0.4 0.0013 18.3 0.4 2.3 2 0 0 2 2 2 1 NADH pyrophosphatase zinc ribbon domain HypA PF01155.19 ORX97456.1 - 0.14 12.2 0.1 0.33 11.0 0.1 1.6 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc-ribbons_6 PF07191.12 ORX97456.1 - 0.15 12.1 0.8 0.32 11.0 0.8 1.4 1 0 0 1 1 1 0 zinc-ribbons Zn-ribbon_8 PF09723.10 ORX97456.1 - 0.2 11.8 2.7 0.45 10.7 1.1 2.2 2 0 0 2 2 2 0 Zinc ribbon domain Voldacs PF03517.13 ORX97457.1 - 2.6e-21 76.2 0.0 4.7e-21 75.4 0.0 1.4 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling DUF669 PF05037.13 ORX97457.1 - 0.15 12.2 0.0 0.27 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF669) WD40 PF00400.32 ORX97458.1 - 3.2e-28 97.4 17.2 2.2e-07 31.5 0.5 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX97458.1 - 9.1e-06 25.9 0.2 1.8 8.9 0.0 4.8 2 2 3 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ PF01011.21 ORX97458.1 - 0.0003 20.6 0.0 5.5 7.1 0.0 4.4 4 0 0 4 4 4 1 PQQ enzyme repeat WD40_like PF17005.5 ORX97458.1 - 0.00065 19.1 0.1 0.014 14.7 0.0 2.2 2 1 1 3 3 3 1 WD40-like domain Nup160 PF11715.8 ORX97458.1 - 0.0024 16.6 0.5 0.092 11.4 0.0 3.1 3 1 2 5 5 5 1 Nucleoporin Nup120/160 BAT PF15915.5 ORX97458.1 - 0.059 13.2 0.1 0.78 9.6 0.0 2.4 2 0 0 2 2 2 0 GAF and HTH_10 associated domain PQQ_3 PF13570.6 ORX97458.1 - 1.9 9.1 7.1 38 5.0 0.0 4.5 5 0 0 5 5 5 0 PQQ-like domain CcmD PF04995.14 ORX97459.1 - 0.055 13.6 0.6 0.11 12.6 0.6 1.5 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) FixQ PF05545.11 ORX97459.1 - 0.25 11.4 0.5 0.48 10.4 0.5 1.4 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ MauE PF07291.11 ORX97497.1 - 1 9.1 4.9 0.66 9.7 2.1 2.0 2 0 0 2 2 2 0 Methylamine utilisation protein MauE Peroxidase_2 PF01328.17 ORX97498.1 - 3.7e-14 53.7 2.1 9.6e-06 26.2 0.1 3.1 2 1 1 3 3 3 3 Peroxidase, family 2 p450 PF00067.22 ORX97499.1 - 8.6e-67 225.9 0.0 1e-66 225.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MPDZ_u10 PF16667.5 ORX97501.1 - 0.041 14.8 0.5 0.089 13.7 0.0 1.8 2 0 0 2 2 2 0 Unstructured region 10 on multiple PDZ protein Qua1 PF16274.5 ORX97501.1 - 0.13 12.1 0.0 17 5.3 0.0 2.6 2 0 0 2 2 2 0 Qua1 domain AA_permease_2 PF13520.6 ORX97502.1 - 8.9e-52 176.3 43.8 1.1e-51 176.0 43.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ORX97502.1 - 5.1e-29 101.2 40.2 7.1e-29 100.7 40.2 1.1 1 0 0 1 1 1 1 Amino acid permease YlaH PF14036.6 ORX97502.1 - 0.11 12.8 0.4 0.11 12.8 0.4 2.7 2 0 0 2 2 2 0 YlaH-like protein GMC_oxred_N PF00732.19 ORX97503.1 - 3.3e-35 121.9 0.0 4.9e-33 114.8 0.0 2.4 1 1 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 ORX97503.1 - 3.9e-27 95.5 0.0 7.4e-27 94.6 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 ORX97503.1 - 0.00013 21.3 0.0 0.0049 16.1 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORX97503.1 - 0.00069 19.8 0.0 0.0024 18.1 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 ORX97503.1 - 0.0017 17.6 0.0 1.5 8.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ORX97503.1 - 0.0027 16.8 0.1 0.044 12.9 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 ORX97503.1 - 0.019 13.7 0.0 0.071 11.8 0.0 1.8 2 0 0 2 2 2 0 HI0933-like protein Lycopene_cycl PF05834.12 ORX97503.1 - 0.034 13.2 0.0 0.05 12.6 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein DAO PF01266.24 ORX97503.1 - 0.037 13.6 0.1 1.1 8.8 0.1 2.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase HHH PF00633.23 ORX97503.1 - 0.22 11.5 0.3 1.8 8.6 0.0 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix motif ADH_zinc_N PF00107.26 ORX97505.1 - 9.6e-26 90.3 1.3 9.6e-26 90.3 1.3 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ORX97505.1 - 1e-19 70.4 0.3 2.2e-19 69.3 0.3 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 ORX97505.1 - 0.009 15.9 0.0 0.039 13.9 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 ORX97505.1 - 0.013 16.6 0.0 0.024 15.7 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase adh_short PF00106.25 ORX97505.1 - 0.13 11.7 0.5 0.27 10.7 0.5 1.6 1 1 0 1 1 1 0 short chain dehydrogenase DUF4532 PF15046.6 ORX97507.1 - 0.12 11.5 0.1 0.16 11.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4532) Toxin_trans PF07952.12 ORX97507.1 - 1.6 7.8 2.8 1.9 7.5 2.8 1.1 1 0 0 1 1 1 0 Clostridium neurotoxin, Translocation domain Sugar_tr PF00083.24 ORX97509.1 - 6.9e-99 331.7 31.5 8e-99 331.5 31.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORX97509.1 - 6.9e-22 77.8 43.2 7.2e-21 74.5 42.8 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily UPF0182 PF03699.13 ORX97509.1 - 0.093 10.8 1.2 0.19 9.8 1.2 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) DHDPS PF00701.22 ORX97510.1 - 1.6e-41 141.9 0.0 2e-41 141.6 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Fungal_trans_2 PF11951.8 ORX97511.1 - 8.2e-23 80.8 0.0 1.1e-22 80.4 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pkinase PF00069.25 ORX97513.1 - 0.006 16.0 0.1 0.0092 15.4 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain zf-RING_2 PF13639.6 ORX97514.1 - 3.8e-09 36.7 11.1 4.5e-09 36.5 11.1 1.1 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 ORX97514.1 - 1e-08 34.9 10.0 1.2e-08 34.6 10.0 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORX97514.1 - 1.4e-08 34.5 12.0 1.7e-08 34.2 12.0 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORX97514.1 - 2.6e-07 30.6 6.8 3.7e-07 30.0 6.8 1.3 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 ORX97514.1 - 5.4e-07 29.4 10.7 7.9e-07 28.8 10.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 ORX97514.1 - 6.6e-07 29.1 7.6 8.3e-07 28.8 7.6 1.1 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 ORX97514.1 - 5.5e-06 26.2 12.2 8e-06 25.7 12.2 1.3 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 ORX97514.1 - 3.4e-05 23.9 10.8 0.00011 22.2 10.8 1.7 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 ORX97514.1 - 0.00014 21.6 9.5 0.00029 20.6 9.5 1.5 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 ORX97514.1 - 0.0002 21.6 8.4 0.00025 21.3 8.4 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger domain DZR PF12773.7 ORX97514.1 - 0.11 12.5 10.5 0.68 10.0 10.5 2.0 1 1 0 1 1 1 0 Double zinc ribbon zf-MIZ PF02891.20 ORX97514.1 - 0.13 12.0 9.9 0.16 11.7 9.9 1.2 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-ANAPC11 PF12861.7 ORX97514.1 - 0.16 12.0 6.7 0.25 11.4 6.7 1.3 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger OrfB_Zn_ribbon PF07282.11 ORX97514.1 - 3.7 7.6 8.5 43 4.1 8.5 2.1 1 1 0 1 1 1 0 Putative transposase DNA-binding domain eIF3g PF12353.8 ORX97515.1 - 0.0015 19.0 0.0 0.006 17.0 0.0 2.1 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G zf-C3HC4 PF00097.25 ORX97515.1 - 0.002 17.9 4.6 0.0047 16.8 4.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORX97515.1 - 0.0037 17.6 3.6 0.0075 16.6 3.6 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 ORX97515.1 - 0.035 14.0 4.1 0.08 12.8 4.1 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 ORX97515.1 - 0.1 12.9 2.1 0.27 11.5 2.1 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 ORX97515.1 - 0.91 9.6 3.0 2.2 8.4 3.0 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-HIT PF04438.16 ORX97515.1 - 1.4 8.8 4.4 8.3 6.4 0.2 2.8 2 0 0 2 2 2 0 HIT zinc finger zf-RING_5 PF14634.6 ORX97515.1 - 1.8 8.6 6.1 3.5 7.6 6.1 1.5 1 0 0 1 1 1 0 zinc-RING finger domain BBE PF08031.12 ORX97516.1 - 4.5e-05 23.4 0.0 7.9e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Berberine and berberine like WW PF00397.26 ORX97541.1 - 2.8e-11 43.3 0.4 7.7e-11 41.9 0.4 1.8 1 0 0 1 1 1 1 WW domain PhoD PF09423.10 ORX97541.1 - 0.0049 15.9 0.1 0.0096 15.0 0.1 1.4 1 0 0 1 1 1 1 PhoD-like phosphatase DUF1640 PF07798.11 ORX97542.1 - 3.5e-54 183.5 13.7 4.3e-54 183.2 13.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) LMBR1 PF04791.16 ORX97542.1 - 0.013 14.4 1.6 0.016 14.2 1.6 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein XhlA PF10779.9 ORX97542.1 - 0.14 12.4 1.5 0.34 11.1 0.2 2.3 2 0 0 2 2 2 0 Haemolysin XhlA 14-3-3 PF00244.20 ORX97543.1 - 3.3e-107 357.1 1.6 3.8e-107 356.8 1.6 1.0 1 0 0 1 1 1 1 14-3-3 protein Orbi_VP5 PF00901.17 ORX97543.1 - 0.086 11.2 1.0 0.14 10.5 1.0 1.3 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 zf-CSL PF05207.13 ORX97544.1 - 3.4e-14 52.3 0.3 3.4e-14 52.3 0.3 1.7 2 0 0 2 2 2 1 CSL zinc finger DnaJ PF00226.31 ORX97544.1 - 5.4e-08 32.9 1.1 4.8e-05 23.4 0.1 2.3 2 0 0 2 2 2 2 DnaJ domain Zn_clus PF00172.18 ORX97546.1 - 4e-06 26.9 9.2 1e-05 25.5 9.2 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ORX97546.1 - 3.9e-05 22.8 1.6 4.6e-05 22.6 0.2 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain C2 PF00168.30 ORX97548.1 - 3.1e-24 85.2 0.0 2.4e-11 43.9 0.0 3.1 3 0 0 3 3 3 2 C2 domain SMP_LBD PF17047.5 ORX97548.1 - 0.1 12.0 0.0 0.97 8.9 0.0 2.2 2 0 0 2 2 2 0 Synaptotagmin-like mitochondrial-lipid-binding domain Aldo_ket_red PF00248.21 ORX97549.1 - 1.1e-39 136.4 0.0 2.2e-37 128.9 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family P3A PF08727.11 ORX97549.1 - 1e-05 24.8 0.2 0.08 12.3 0.9 3.5 3 0 0 3 3 3 2 Poliovirus 3A protein like IF-2B PF01008.17 ORX97550.1 - 8.2e-74 248.3 1.0 1e-73 248.1 1.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family CLZ PF16526.5 ORX97551.1 - 0.00093 19.5 0.2 0.0012 19.1 0.2 1.2 1 0 0 1 1 1 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DASH_Spc19 PF08287.11 ORX97551.1 - 0.017 15.1 1.3 0.018 15.0 1.3 1.2 1 1 0 1 1 1 0 Spc19 KxDL PF10241.9 ORX97551.1 - 0.07 13.4 0.0 0.089 13.1 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein DUF4407 PF14362.6 ORX97551.1 - 0.079 12.3 0.5 0.08 12.3 0.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) IL11 PF07400.11 ORX97551.1 - 0.092 12.4 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 Interleukin 11 Sas10_Utp3 PF04000.15 ORX97551.1 - 0.15 12.7 1.3 0.21 12.3 1.3 1.2 1 0 0 1 1 1 0 Sas10/Utp3/C1D family EF-hand_4 PF12763.7 ORX97552.1 - 9.9e-27 92.9 0.2 2.2e-13 50.1 0.0 2.9 3 0 0 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.6 ORX97552.1 - 1.4e-05 25.4 0.3 0.019 15.4 0.0 3.6 3 0 0 3 3 3 2 EF-hand domain pair DUF1720 PF08226.11 ORX97552.1 - 0.00049 20.5 25.5 0.00049 20.5 25.5 7.3 5 2 2 7 7 7 2 Domain of unknown function (DUF1720) E3_binding PF02817.17 ORX97552.1 - 0.019 15.3 0.1 0.058 13.8 0.1 1.8 1 0 0 1 1 1 0 e3 binding domain EF-hand_8 PF13833.6 ORX97552.1 - 0.022 14.6 0.1 18 5.2 0.0 3.3 3 0 0 3 3 3 0 EF-hand domain pair EF-hand_6 PF13405.6 ORX97552.1 - 0.13 12.2 0.1 5.1 7.3 0.1 3.0 3 0 0 3 3 3 0 EF-hand domain Abhydrolase_4 PF08386.10 ORX97553.1 - 5.1e-19 68.3 0.0 9.9e-19 67.4 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.20 ORX97553.1 - 2.3e-16 60.2 0.0 8.4e-16 58.4 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold RNA_pol_L_2 PF13656.6 ORX97554.1 - 4.2e-21 74.5 0.0 5.2e-21 74.2 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 ORX97554.1 - 0.00012 21.5 0.0 0.00028 20.3 0.0 1.6 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Glyco_hydro_79C PF16862.5 ORX97555.1 - 3e-23 82.6 0.5 8.2e-23 81.2 0.5 1.8 1 0 0 1 1 1 1 Glycosyl hydrolase family 79 C-terminal beta domain Glyco_hydro_79n PF03662.14 ORX97555.1 - 0.056 12.4 0.6 0.92 8.4 0.1 2.7 4 0 0 4 4 4 0 Glycosyl hydrolase family 79, N-terminal domain NAD_binding_4 PF07993.12 ORX97556.1 - 8e-41 139.9 0.0 1.2e-40 139.3 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 ORX97556.1 - 4.7e-20 71.6 0.0 9.4e-20 70.6 0.0 1.4 1 1 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 ORX97556.1 - 4.8e-11 42.6 0.0 7.7e-11 41.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 ORX97556.1 - 4.8e-07 30.0 0.2 1.4e-06 28.5 0.2 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site KR PF08659.10 ORX97556.1 - 0.00054 19.9 0.0 0.028 14.3 0.2 2.5 2 1 0 2 2 2 1 KR domain 3Beta_HSD PF01073.19 ORX97556.1 - 0.0018 17.3 0.0 0.0062 15.6 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 ORX97556.1 - 0.0058 17.1 0.0 0.011 16.1 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.13 ORX97556.1 - 0.058 12.9 0.0 0.093 12.3 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family DapB_N PF01113.20 ORX97556.1 - 0.18 11.9 0.0 0.37 10.9 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus DXP_reductoisom PF02670.16 ORX97556.1 - 0.18 12.5 0.0 0.37 11.5 0.0 1.5 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Polysacc_synt_2 PF02719.15 ORX97556.1 - 0.22 10.7 0.0 0.64 9.1 0.0 1.7 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein p450 PF00067.22 ORX97557.1 - 2.2e-73 247.6 0.0 2.9e-73 247.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 K-box PF01486.17 ORX97557.1 - 0.054 13.7 0.0 0.2 11.8 0.0 1.9 2 0 0 2 2 2 0 K-box region Pkinase PF00069.25 ORX97558.1 - 1e-72 244.7 0.0 1.4e-72 244.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX97558.1 - 8.3e-35 120.3 0.0 1.1e-34 119.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 ORX97558.1 - 1.6e-16 60.4 0.1 3.2e-16 59.4 0.1 1.5 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.6 ORX97558.1 - 2.5e-10 40.1 0.0 1.3e-09 37.8 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 ORX97558.1 - 5.3e-06 25.5 0.0 1.1e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Yop-YscD_cpl PF16697.5 ORX97558.1 - 1.6e-05 25.1 0.0 3.6e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Kdo PF06293.14 ORX97558.1 - 0.012 15.0 0.1 0.023 14.0 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2961 PF11175.8 ORX97558.1 - 0.013 15.2 0.0 5.7 6.5 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2961) Pox_ser-thr_kin PF05445.11 ORX97558.1 - 0.12 11.3 0.0 0.17 10.8 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Autophagy_act_C PF03987.15 ORX97559.1 - 1.4e-14 54.4 2.7 5.5e-14 52.5 2.3 2.0 2 0 0 2 2 2 1 Autophagocytosis associated protein, active-site domain CorA PF01544.18 ORX97560.1 - 1.3e-07 31.3 1.7 2.5e-07 30.3 1.7 1.5 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Fig1 PF12351.8 ORX97561.1 - 9.6e-33 113.7 0.9 9.6e-33 113.7 0.9 1.7 1 1 1 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.12 ORX97561.1 - 0.0012 18.5 11.9 0.0024 17.6 11.9 1.5 1 1 0 1 1 1 1 SUR7/PalI family DUF2207 PF09972.9 ORX97561.1 - 3.9 6.1 7.0 4 6.1 6.1 1.5 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Caps_synth_CapC PF14102.6 ORX97561.1 - 5.3 7.5 9.9 15 6.1 2.9 3.1 2 1 1 3 3 3 0 Capsule biosynthesis CapC DAGAT PF03982.13 ORX97595.1 - 7.5e-70 235.2 0.0 8.4e-70 235.0 0.0 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase FIT1_2 PF17357.2 ORX97596.1 - 0.014 15.4 3.9 0.061 13.4 3.9 2.0 1 0 0 1 1 1 0 Facilitor Of iron transport 1 and 2 Inhibitor_Mig-6 PF11555.8 ORX97596.1 - 0.04 14.0 0.3 14 5.9 0.1 3.1 2 0 0 2 2 2 0 EGFR receptor inhibitor Mig-6 zf-C2HE PF16278.5 ORX97596.1 - 2.5 8.6 7.3 5.3 7.6 0.3 3.0 2 1 1 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger Acyl_transf_3 PF01757.22 ORX97597.1 - 0.001 18.2 38.8 0.004 16.3 38.8 2.0 1 1 0 1 1 1 1 Acyltransferase family Glyco_trans_2_3 PF13632.6 ORX97598.1 - 1.4e-21 77.3 2.5 1.4e-21 77.3 2.5 2.2 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 ORX97598.1 - 8.5e-19 68.4 0.0 1.1e-18 68.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 ORX97598.1 - 7.5e-06 25.5 0.0 1.1e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 ORX97598.1 - 2.5e-05 24.2 0.0 3.8e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_hydro_16 PF00722.21 ORX97599.1 - 6.2e-08 32.3 0.9 4.4e-07 29.5 0.9 2.2 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 Acyl_transf_3 PF01757.22 ORX97599.1 - 2e-05 23.8 41.2 2e-05 23.8 41.2 1.8 2 0 0 2 2 2 1 Acyltransferase family Erv26 PF04148.13 ORX97601.1 - 2.5e-91 305.1 0.0 2.9e-91 304.9 0.0 1.0 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 Cytochrom_C_asm PF01578.20 ORX97601.1 - 0.0073 16.1 0.4 0.0073 16.1 0.4 1.7 1 1 1 2 2 2 1 Cytochrome C assembly protein AA_permease PF00324.21 ORX97604.1 - 1.1e-64 218.9 32.0 5.6e-64 216.5 32.0 1.8 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ORX97604.1 - 5.3e-22 78.2 23.0 6.7e-22 77.9 23.0 1.1 1 0 0 1 1 1 1 Amino acid permease DUF3413 PF11893.8 ORX97604.1 - 0.56 9.3 14.0 0.096 11.8 8.6 2.5 3 1 0 3 3 3 0 Domain of unknown function (DUF3413) DUF3675 PF12428.8 ORX97604.1 - 0.61 10.6 3.4 0.49 11.0 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3675) WBS_methylT PF12589.8 ORX97605.1 - 1.5e-14 54.5 9.8 2.7e-14 53.7 9.8 1.4 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_25 PF13649.6 ORX97605.1 - 2.9e-08 34.3 0.0 5.2e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORX97605.1 - 8.7e-08 32.7 0.0 1.6e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORX97605.1 - 0.0064 17.2 0.0 0.016 15.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 ORX97605.1 - 0.016 15.0 0.0 0.027 14.2 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 ORX97605.1 - 0.017 14.9 0.0 0.026 14.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 ORX97605.1 - 0.078 12.8 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Iso_dh PF00180.20 ORX97606.1 - 1.3e-84 284.3 0.0 1.6e-84 284.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase NAD_binding_2 PF03446.15 ORX97607.1 - 2.4e-29 102.5 0.0 3.6e-29 102.0 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 ORX97607.1 - 1.1e-20 74.0 0.0 1.7e-20 73.5 0.0 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 ORX97607.1 - 0.0017 18.9 0.0 0.004 17.7 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 ORX97607.1 - 0.0025 17.2 0.0 0.0056 16.0 0.0 1.5 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NTF2 PF02136.20 ORX97608.1 - 0.0086 16.6 0.0 0.055 14.0 0.0 2.1 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RP-C PF03428.13 ORX97609.1 - 0.25 11.0 5.8 0.84 9.3 6.3 1.7 2 0 0 2 2 2 0 Replication protein C N-terminal domain APG6_N PF17675.1 ORX97609.1 - 3 8.4 17.7 0.22 12.1 10.9 2.6 2 0 0 2 2 2 0 Apg6 coiled-coil region GAS PF13851.6 ORX97609.1 - 7.4 5.9 19.3 14 4.9 19.3 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Ribosomal_L38e PF01781.18 ORX97611.1 - 3.9e-33 113.4 3.9 4.3e-33 113.2 3.9 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family CLTH PF10607.9 ORX97611.1 - 0.0099 15.8 0.3 0.011 15.6 0.3 1.1 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain HipN PF18253.1 ORX97611.1 - 0.14 11.9 0.4 0.63 9.8 0.0 2.1 2 0 0 2 2 2 0 Hsp70-interacting protein N N-terminal domain Lactamase_B_2 PF12706.7 ORX97612.1 - 7.8e-15 54.9 0.2 1.5e-14 54.0 0.2 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 ORX97612.1 - 2e-11 44.1 0.5 1.5e-10 41.2 0.5 2.0 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 ORX97612.1 - 0.021 14.8 2.3 0.021 14.8 2.3 2.8 3 1 0 3 3 3 0 Metallo-beta-lactamase superfamily Glyco_hydro_47 PF01532.20 ORX97613.1 - 6.2e-170 566.0 0.0 7.6e-170 565.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 FMO-like PF00743.19 ORX97615.1 - 2.3e-16 59.3 0.1 6e-16 58.0 0.0 1.6 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 ORX97615.1 - 1.3e-12 47.6 0.0 1.4e-10 40.9 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ORX97615.1 - 1e-11 44.7 0.0 5.7e-10 38.9 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ORX97615.1 - 1.9e-10 40.4 0.0 7.4e-08 31.9 0.0 2.2 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 ORX97615.1 - 3.8e-08 33.4 0.0 6.5e-07 29.5 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 ORX97615.1 - 0.00012 22.1 0.6 0.038 14.0 0.0 3.7 3 1 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 ORX97615.1 - 0.002 18.6 0.4 2.3 8.8 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 ORX97615.1 - 0.027 14.6 0.1 0.19 11.8 0.0 2.1 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DAO PF01266.24 ORX97615.1 - 0.031 13.9 0.5 11 5.4 0.0 3.2 3 0 0 3 3 3 0 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.19 ORX97615.1 - 0.038 13.4 0.0 0.079 12.3 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 ORX97615.1 - 0.12 12.0 1.0 0.73 9.4 0.1 2.1 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_7 PF13241.6 ORX97615.1 - 0.22 12.0 0.0 29 5.2 0.0 2.7 3 0 0 3 3 3 0 Putative NAD(P)-binding Gelsolin PF00626.22 ORX97616.1 - 4.4e-26 90.6 0.2 2.7e-09 36.8 0.0 3.2 3 0 0 3 3 3 3 Gelsolin repeat DUF1292 PF06949.11 ORX97616.1 - 0.047 14.7 0.4 0.26 12.3 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1292) MFS_1 PF07690.16 ORX97617.1 - 5.9e-31 107.7 17.8 5.9e-31 107.7 17.8 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily GHMP_kinases_N PF00288.26 ORX97617.1 - 0.072 13.3 0.9 1.9 8.8 0.1 2.7 2 0 0 2 2 2 0 GHMP kinases N terminal domain Phage_holin_4_1 PF05105.12 ORX97617.1 - 0.21 11.7 3.2 8.7 6.5 1.3 3.0 3 0 0 3 3 3 0 Bacteriophage holin family Esterase PF00756.20 ORX97618.1 - 7.7e-10 38.8 0.0 2.7e-09 37.1 0.0 1.8 1 1 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 ORX97618.1 - 1.6e-06 27.5 0.0 2.3e-05 23.8 0.0 2.0 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 ORX97618.1 - 3.8e-06 26.5 0.0 7.5e-06 25.6 0.0 1.5 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 ORX97618.1 - 0.2 11.5 0.0 0.38 10.5 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase ABC2_membrane_2 PF12679.7 ORX97620.1 - 1.2 8.4 8.2 1.7 7.9 8.2 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein SLATT_5 PF18160.1 ORX97620.1 - 2.3 7.5 8.5 6.2 6.1 3.1 2.2 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 Shadoo PF14999.6 ORX97621.1 - 0.072 13.2 7.3 0.084 13.0 7.3 1.1 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective BioY PF02632.14 ORX97621.1 - 0.41 10.7 9.4 0.47 10.5 9.4 1.0 1 0 0 1 1 1 0 BioY family Dot_icm_IcmQ PF09475.10 ORX97637.1 - 0.13 11.7 0.1 0.16 11.5 0.1 1.1 1 0 0 1 1 1 0 Dot/Icm secretion system protein (dot_icm_IcmQ) Hep_core_N PF08290.11 ORX97638.1 - 0.01 15.7 0.3 0.017 15.0 0.3 1.3 1 0 0 1 1 1 0 Hepatitis core protein, putative zinc finger ISK_Channel PF02060.15 ORX97675.1 - 0.17 11.6 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 Slow voltage-gated potassium channel Abhydrolase_6 PF12697.7 ORX97677.1 - 0.034 14.8 0.1 0.18 12.4 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase family DUF3693 PF12472.8 ORX97677.1 - 0.14 11.9 0.0 0.33 10.6 0.0 1.6 1 0 0 1 1 1 0 Phage related protein Pkinase PF00069.25 ORX97678.1 - 2.8e-24 85.9 0.0 4e-24 85.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX97678.1 - 1.5e-19 70.4 0.0 2.4e-19 69.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORX97678.1 - 0.0054 15.6 0.0 0.0066 15.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 ORX97678.1 - 0.0073 15.7 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 ORX97678.1 - 0.011 15.7 0.0 0.02 14.8 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 ORX97678.1 - 0.03 13.7 0.0 0.049 13.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 ORX97678.1 - 0.12 11.3 0.0 0.18 10.7 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH_6_hur PF04655.14 ORX97678.1 - 0.17 11.2 0.0 0.33 10.3 0.0 1.4 1 0 0 1 1 1 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase Yip1 PF04893.17 ORX97679.1 - 0.062 13.0 6.9 0.023 14.4 4.3 1.6 2 0 0 2 2 2 0 Yip1 domain Herpes_UL43 PF05072.13 ORX97679.1 - 0.072 12.2 1.2 0.1 11.7 1.2 1.1 1 0 0 1 1 1 0 Herpesvirus UL43 protein Pkinase PF00069.25 ORX97680.1 - 2.3e-24 86.2 0.0 3.7e-24 85.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX97680.1 - 3.6e-15 55.9 0.0 5.9e-15 55.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_3 PF13606.6 ORX97680.1 - 5.6e-05 23.2 0.0 0.02 15.4 0.0 4.6 4 0 0 4 4 4 1 Ankyrin repeat Ank_4 PF13637.6 ORX97680.1 - 0.00016 22.1 0.0 0.23 12.1 0.0 3.9 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank PF00023.30 ORX97680.1 - 0.00037 20.8 0.0 0.2 12.2 0.0 3.7 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 ORX97680.1 - 0.0027 18.0 0.0 0.038 14.3 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Kdo PF06293.14 ORX97680.1 - 0.0042 16.5 0.1 0.0076 15.6 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Ank_2 PF12796.7 ORX97680.1 - 0.014 16.0 0.0 0.53 10.9 0.0 3.1 3 0 0 3 3 3 0 Ankyrin repeats (3 copies) Kinase-like PF14531.6 ORX97680.1 - 0.024 14.0 0.0 0.038 13.3 0.0 1.2 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 ORX97680.1 - 0.025 14.5 0.2 0.081 12.8 0.1 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family Phage_sheath_1 PF04984.14 ORX97680.1 - 0.19 11.6 0.0 0.34 10.7 0.0 1.4 1 0 0 1 1 1 0 Phage tail sheath protein subtilisin-like domain Asparaginase PF00710.20 ORX97681.1 - 2.8e-35 121.6 0.0 4.5e-35 120.9 0.0 1.3 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 ORX97681.1 - 2.3e-12 47.1 0.0 5.7e-12 45.9 0.0 1.7 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain PA PF02225.22 ORX97681.1 - 0.071 13.1 0.1 0.19 11.8 0.1 1.7 1 0 0 1 1 1 0 PA domain Sod_Fe_C PF02777.18 ORX97683.1 - 7.5e-36 122.4 0.0 1.3e-35 121.6 0.0 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 ORX97683.1 - 1.8e-19 70.0 5.4 1.8e-19 70.0 5.4 2.0 2 1 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Esterase_phd PF10503.9 ORX97684.1 - 4.5e-22 78.6 1.2 6.1e-22 78.2 1.2 1.1 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 ORX97684.1 - 4.6e-06 26.2 0.5 5.9e-06 25.9 0.5 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 ORX97684.1 - 0.00015 21.6 0.1 0.00021 21.1 0.1 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Esterase PF00756.20 ORX97684.1 - 0.0011 18.7 0.8 0.0014 18.3 0.8 1.4 1 1 0 1 1 1 1 Putative esterase Baculo_E66 PF04850.12 ORX97684.1 - 0.0049 15.7 0.2 0.0071 15.2 0.2 1.2 1 0 0 1 1 1 1 Baculovirus E66 occlusion-derived virus envelope protein Tannase PF07519.11 ORX97684.1 - 0.013 14.4 0.2 0.016 14.1 0.2 1.3 1 0 0 1 1 1 0 Tannase and feruloyl esterase Abhydrolase_1 PF00561.20 ORX97684.1 - 0.019 14.6 0.2 0.025 14.2 0.2 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 ORX97684.1 - 0.029 14.2 0.1 0.05 13.5 0.1 1.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold COesterase PF00135.28 ORX97684.1 - 0.036 13.0 0.6 0.041 12.8 0.5 1.3 1 1 0 1 1 1 0 Carboxylesterase family BAAT_C PF08840.11 ORX97684.1 - 0.042 13.8 0.2 0.059 13.3 0.2 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Prok_Ub PF14454.6 ORX97684.1 - 0.15 11.7 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic Ubiquitin DUF2920 PF11144.8 ORX97684.1 - 0.18 10.9 0.3 0.26 10.4 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) Sugar_tr PF00083.24 ORX97685.1 - 2.3e-120 402.5 21.6 7.8e-120 400.8 21.6 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORX97685.1 - 1.3e-27 96.7 32.7 8.5e-20 71.0 10.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Peptidase_M28 PF04389.17 ORX97687.1 - 2.8e-33 115.3 0.0 8.4e-33 113.7 0.0 1.7 1 1 0 1 1 1 1 Peptidase family M28 Glyco_hydro_61 PF03443.14 ORX97689.1 - 2.5e-58 197.4 0.1 3.1e-58 197.1 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 adh_short PF00106.25 ORX97690.1 - 3.5e-18 65.8 0.0 5.5e-18 65.1 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORX97690.1 - 5.6e-11 42.4 0.1 2.5e-09 37.1 0.1 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase AdoHcyase_NAD PF00670.21 ORX97690.1 - 0.058 13.5 0.3 0.2 11.7 0.1 1.8 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KR PF08659.10 ORX97690.1 - 0.2 11.5 1.0 0.54 10.1 0.6 2.0 1 1 0 1 1 1 0 KR domain Fib_alpha PF08702.10 ORX97746.1 - 0.0014 18.8 26.1 0.0034 17.6 11.5 2.3 2 0 0 2 2 2 2 Fibrinogen alpha/beta chain family Fez1 PF06818.15 ORX97746.1 - 0.0024 18.3 23.9 0.0024 18.3 23.9 3.0 1 1 2 3 3 3 2 Fez1 ATG16 PF08614.11 ORX97746.1 - 0.014 15.7 13.3 0.014 15.7 13.3 2.6 1 1 0 2 2 2 0 Autophagy protein 16 (ATG16) BLOC1_2 PF10046.9 ORX97746.1 - 0.018 15.3 1.3 0.018 15.3 1.3 3.9 3 1 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Med9 PF07544.13 ORX97746.1 - 0.019 15.1 3.9 0.019 15.1 3.9 5.2 3 2 2 5 5 4 0 RNA polymerase II transcription mediator complex subunit 9 Laminin_II PF06009.12 ORX97746.1 - 0.064 13.3 22.1 0.047 13.7 1.9 3.5 2 1 1 3 3 3 0 Laminin Domain II Spc7 PF08317.11 ORX97746.1 - 0.44 9.4 43.0 0.091 11.6 17.1 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF1664 PF07889.12 ORX97746.1 - 0.46 10.5 15.7 0.055 13.5 2.8 3.0 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) TMPIT PF07851.13 ORX97746.1 - 2.9 7.0 23.9 1.1 8.4 7.3 2.5 1 1 2 3 3 3 0 TMPIT-like protein DUF4686 PF15742.5 ORX97746.1 - 3.2 6.8 42.6 0.52 9.4 11.3 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4686) Filament PF00038.21 ORX97746.1 - 4.8 6.7 34.1 0.8 9.2 13.4 2.9 1 1 0 2 2 2 0 Intermediate filament protein PhoU PF01895.19 ORX97746.1 - 5.1 7.6 8.9 0.78 10.2 0.5 3.3 2 1 1 3 3 3 0 PhoU domain FlaC_arch PF05377.11 ORX97746.1 - 5.9 7.4 16.7 8.2 6.9 1.3 4.9 3 1 0 4 4 4 0 Flagella accessory protein C (FlaC) ATP_transf PF09830.9 ORX97748.1 - 5.4e-12 45.7 0.0 9.5e-12 44.9 0.0 1.4 1 0 0 1 1 1 1 ATP adenylyltransferase p450 PF00067.22 ORX97749.1 - 4.5e-50 170.7 0.0 7.5e-50 170.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 ORX97750.1 - 8.3e-37 126.9 42.9 2.3e-36 125.4 42.9 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 ORX97750.1 - 3.8e-11 42.1 20.6 4.4e-11 41.9 20.6 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Mpv17_PMP22 PF04117.12 ORX97750.1 - 0.047 13.9 0.4 0.22 11.8 0.2 2.3 2 0 0 2 2 2 0 Mpv17 / PMP22 family Sugar_tr PF00083.24 ORX97751.1 - 2.5e-88 297.0 21.7 2.8e-88 296.7 21.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORX97751.1 - 1.2e-32 113.2 17.8 1.2e-32 113.2 17.8 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2826 PF11442.8 ORX97751.1 - 0.095 12.5 0.2 0.2 11.5 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2826) RseC_MucC PF04246.12 ORX97751.1 - 0.16 11.9 1.0 16 5.4 0.1 2.9 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Beta-lactamase PF00144.24 ORX97752.1 - 4.2e-43 147.8 0.0 8.7e-43 146.8 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.8 ORX97752.1 - 4e-07 30.5 0.0 7.8e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) PLD_C PF12357.8 ORX97752.1 - 0.045 13.7 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 Phospholipase D C terminal Peptidase_S11 PF00768.20 ORX97752.1 - 0.11 12.0 0.0 0.52 9.7 0.0 1.9 2 0 0 2 2 2 0 D-alanyl-D-alanine carboxypeptidase MFS_1 PF07690.16 ORX97753.1 - 8.6e-25 87.4 61.3 8.3e-24 84.2 45.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 ORX97753.1 - 0.14 10.5 11.1 0.0094 14.4 5.1 1.8 2 0 0 2 2 2 0 Transmembrane secretion effector Myco_19_kDa PF05481.12 ORX97754.1 - 0.0094 16.2 0.6 0.76 10.1 0.1 2.6 2 0 0 2 2 2 2 Mycobacterium 19 kDa lipoprotein antigen DUF4407 PF14362.6 ORX97756.1 - 0.037 13.4 0.5 0.08 12.3 0.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1640 PF07798.11 ORX97756.1 - 0.067 13.2 0.1 0.15 12.1 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) YscO PF07321.12 ORX97756.1 - 0.56 10.2 5.2 0.12 12.3 0.9 1.8 2 0 0 2 2 2 0 Type III secretion protein YscO BRE1 PF08647.11 ORX97757.1 - 0.13 12.3 0.7 8.7 6.5 0.0 2.1 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase zf-His_Me_endon PF05551.11 ORX97758.1 - 1.8e-09 37.8 5.2 3.2e-09 37.0 5.2 1.4 1 0 0 1 1 1 1 Zinc-binding loop region of homing endonuclease zf-B_box PF00643.24 ORX97760.1 - 0.056 13.6 1.3 0.36 11.0 1.3 2.4 2 0 0 2 2 2 0 B-box zinc finger Mod_r PF07200.13 ORX97761.1 - 0.22 11.6 13.5 0.089 12.9 1.3 3.3 3 1 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein Rootletin PF15035.6 ORX97761.1 - 0.65 10.0 10.9 0.035 14.1 3.7 2.4 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion V_ATPase_I PF01496.19 ORX97761.1 - 0.96 7.3 3.9 1.7 6.5 0.7 2.3 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DivIC PF04977.15 ORX97761.1 - 3.7 7.4 9.0 0.75 9.6 1.2 3.1 3 0 0 3 3 3 0 Septum formation initiator CENP-H PF05837.12 ORX97761.1 - 3.9 7.9 11.1 0.86 10.0 1.4 2.7 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Cep57_CLD_2 PF14197.6 ORX97761.1 - 5.4 7.2 10.5 10 6.3 0.2 4.0 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 FliD_N PF02465.18 ORX97761.1 - 6.4 7.5 9.1 1 10.1 0.7 3.0 3 0 0 3 3 3 0 Flagellar hook-associated protein 2 N-terminus Seryl_tRNA_N PF02403.22 ORX97761.1 - 9.1 6.6 12.1 0.19 12.0 1.5 2.9 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain But2 PF09792.9 ORX97793.1 - 5.5e-08 33.3 0.0 7e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain Tyrosinase PF00264.20 ORX97795.1 - 5.1e-52 177.4 0.2 6.7e-52 177.0 0.2 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase NACHT PF05729.12 ORX97796.1 - 3.5e-11 43.3 0.1 9e-05 22.4 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_16 PF13191.6 ORX97796.1 - 6.4e-10 39.7 0.0 0.0015 19.0 0.0 2.9 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 ORX97796.1 - 6.2e-06 26.5 0.0 0.11 12.8 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_18 PF13238.6 ORX97796.1 - 3e-05 24.6 0.0 0.19 12.2 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA_33 PF13671.6 ORX97796.1 - 0.00015 22.0 0.1 0.16 12.1 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_14 PF13173.6 ORX97796.1 - 0.00043 20.3 0.0 0.17 11.9 0.0 3.8 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.6 ORX97796.1 - 0.0008 19.8 0.0 0.43 11.0 0.0 2.9 2 0 0 2 2 2 1 AAA domain Ploopntkinase3 PF18751.1 ORX97796.1 - 0.0021 18.0 0.0 1.7 8.5 0.0 2.7 2 0 0 2 2 2 2 P-loop Nucleotide Kinase3 ATP_bind_1 PF03029.17 ORX97796.1 - 0.0021 17.9 0.0 1.3 8.7 0.0 2.5 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein NB-ARC PF00931.22 ORX97796.1 - 0.0064 15.7 0.0 4.1 6.5 0.0 3.0 3 0 0 3 3 3 2 NB-ARC domain APS_kinase PF01583.20 ORX97796.1 - 0.017 15.0 0.0 0.4 10.6 0.0 2.3 2 0 0 2 2 2 0 Adenylylsulphate kinase WD40 PF00400.32 ORX97796.1 - 0.038 14.9 1.6 45 5.2 0.0 5.6 7 0 0 7 7 3 0 WD domain, G-beta repeat MeaB PF03308.16 ORX97796.1 - 0.063 12.3 0.0 10 5.0 0.0 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_29 PF13555.6 ORX97796.1 - 0.064 13.0 0.2 3.8 7.3 0.0 3.2 3 0 0 3 3 3 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 ORX97796.1 - 0.069 13.2 0.1 10 6.3 0.0 3.3 3 0 0 3 3 3 0 50S ribosome-binding GTPase Zeta_toxin PF06414.12 ORX97796.1 - 0.072 12.4 0.0 8.5 5.6 0.0 3.2 3 0 0 3 3 3 0 Zeta toxin ATPase_2 PF01637.18 ORX97796.1 - 0.074 13.0 0.2 2.4 8.0 0.0 2.8 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea AAA_30 PF13604.6 ORX97796.1 - 0.19 11.4 0.0 6 6.5 0.0 2.7 3 0 0 3 3 3 0 AAA domain Fructosamin_kin PF03881.14 ORX97797.1 - 4e-25 88.6 0.2 5.2e-25 88.2 0.2 1.2 1 0 0 1 1 1 1 Fructosamine kinase DUF4070 PF13282.6 ORX97797.1 - 0.058 13.5 0.1 0.11 12.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4070) DUF2318 PF10080.9 ORX97798.1 - 0.03 14.4 0.0 0.056 13.6 0.0 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) zinc-ribbons_6 PF07191.12 ORX97798.1 - 0.077 13.0 0.6 0.077 13.0 0.6 1.6 2 0 0 2 2 2 0 zinc-ribbons zf-TFIIB PF13453.6 ORX97798.1 - 0.28 10.5 1.9 0.74 9.2 1.9 1.7 1 0 0 1 1 1 0 Transcription factor zinc-finger SET PF00856.28 ORX97799.1 - 2e-15 57.6 0.0 7.8e-15 55.7 0.0 1.9 1 1 0 1 1 1 1 SET domain zf-C2HCIx2C PF10782.9 ORX97799.1 - 0.0094 15.9 0.6 0.027 14.4 0.6 1.7 1 0 0 1 1 1 1 Zinc-finger YHS PF04945.13 ORX97799.1 - 0.11 12.6 0.1 1.9 8.6 0.1 2.4 2 0 0 2 2 2 0 YHS domain 4HBT PF03061.22 ORX97800.1 - 1.1e-07 32.1 0.1 1.9e-07 31.4 0.1 1.3 1 0 0 1 1 1 1 Thioesterase superfamily DUF4918 PF16265.5 ORX97800.1 - 0.17 11.3 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4918) Metallopep PF12044.8 ORX97802.1 - 3.5e-132 441.0 0.0 4.2e-132 440.8 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family Jacalin PF01419.17 ORX97802.1 - 0.03 14.3 0.0 0.06 13.3 0.0 1.4 1 0 0 1 1 1 0 Jacalin-like lectin domain Lipoprotein_15 PF03640.15 ORX97802.1 - 0.068 12.7 1.7 0.21 11.2 1.7 1.8 1 0 0 1 1 1 0 Secreted repeat of unknown function Peptidase_M66 PF10462.9 ORX97802.1 - 0.13 11.2 0.2 0.26 10.2 0.2 1.4 1 0 0 1 1 1 0 Peptidase M66 Polyketide_cyc2 PF10604.9 ORX97803.1 - 0.00079 19.7 0.0 0.0023 18.2 0.0 1.8 2 0 0 2 2 2 1 Polyketide cyclase / dehydrase and lipid transport HTH_23 PF13384.6 ORX97803.1 - 0.047 13.5 0.0 0.48 10.3 0.0 2.3 2 0 0 2 2 2 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 ORX97803.1 - 0.16 12.2 0.0 0.28 11.5 0.0 1.3 1 0 0 1 1 1 0 Transposase DDE_3 PF13358.6 ORX97804.1 - 0.0035 17.1 0.0 0.0043 16.8 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease zf-CCCH PF00642.24 ORX97805.1 - 2.8e-09 36.6 15.0 3.1e-07 30.1 2.5 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.22 ORX97805.1 - 1.5e-06 27.9 0.0 2.8e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 ORX97805.1 - 0.0059 16.6 3.3 0.0059 16.6 3.3 2.5 2 0 0 2 2 2 1 Zinc finger domain Torus PF16131.5 ORX97805.1 - 0.01 16.5 2.8 0.5 11.1 0.2 2.5 2 0 0 2 2 2 0 Torus domain zf-CCCH_3 PF15663.5 ORX97805.1 - 0.024 14.9 2.8 0.15 12.3 0.3 2.3 2 0 0 2 2 2 0 Zinc-finger containing family PAM2 PF07145.15 ORX97806.1 - 0.26 11.0 6.6 7.3 6.5 3.0 3.1 2 0 0 2 2 2 0 Ataxin-2 C-terminal region UL45 PF05473.12 ORX97806.1 - 0.28 10.8 1.6 0.62 9.7 0.0 2.1 2 1 1 3 3 3 0 UL45 protein, carbohydrate-binding C-type lectin-like DUF3605 PF12239.8 ORX97807.1 - 3.7e-54 183.2 4.7 4.5e-54 182.9 4.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) HTH_Tnp_ISL3 PF13542.6 ORX97807.1 - 0.21 11.1 0.9 18 4.8 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 HMG-CoA_red PF00368.18 ORX97809.1 - 2.2e-140 467.8 9.2 2.9e-140 467.5 9.2 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HPIH PF13323.6 ORX97809.1 - 1.8e-43 148.1 0.0 3.2e-43 147.3 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain with HPIH motif Sterol-sensing PF12349.8 ORX97809.1 - 2.4e-16 59.9 4.5 5.1e-16 58.9 4.5 1.5 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 ORX97809.1 - 0.0012 17.0 5.0 0.0012 17.0 5.0 1.5 2 0 0 2 2 2 1 Patched family Glyco_hydro_76 PF03663.14 ORX97810.1 - 6.6e-89 299.0 2.8 8.4e-89 298.6 2.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 ORX97810.1 - 0.00067 18.8 0.6 0.1 11.6 0.1 2.5 2 1 0 2 2 2 2 Glycosyl Hydrolase Family 88 p450 PF00067.22 ORX97811.1 - 4.2e-46 157.7 0.0 7.7e-46 156.8 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Fungal_trans_2 PF11951.8 ORX97812.1 - 5.2e-07 28.8 0.2 3.3e-06 26.2 0.2 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORX97812.1 - 0.0038 17.3 2.2 0.0066 16.6 2.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF498 PF04430.14 ORX97815.1 - 1.3e-29 102.4 0.0 1.9e-29 101.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) Ank_2 PF12796.7 ORX97816.1 - 0.001 19.6 0.0 0.0012 19.4 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 ORX97816.1 - 0.0018 18.7 0.0 0.0022 18.4 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeat Phage_Gp17 PF17549.2 ORX97816.1 - 0.035 14.1 0.1 0.036 14.1 0.1 1.0 1 0 0 1 1 1 0 Gene Product 17 Ank_5 PF13857.6 ORX97816.1 - 0.058 13.7 0.0 0.065 13.6 0.0 1.1 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank_4 PF13637.6 ORX97816.1 - 0.082 13.5 0.1 0.95 10.1 0.0 1.9 1 1 1 2 2 2 0 Ankyrin repeats (many copies) bZIP_1 PF00170.21 ORX97848.1 - 7.2e-06 26.0 10.6 1.7e-05 24.8 10.6 1.6 1 0 0 1 1 1 1 bZIP transcription factor Mito_fiss_reg PF05308.11 ORX97848.1 - 0.0075 16.4 3.9 0.014 15.5 3.9 1.4 1 0 0 1 1 1 1 Mitochondrial fission regulator ABC_tran_Xtn PF12848.7 ORX97848.1 - 0.046 13.8 2.4 0.082 13.0 2.4 1.3 1 0 0 1 1 1 0 ABC transporter YabA PF06156.13 ORX97848.1 - 0.05 14.2 0.2 0.1 13.2 0.2 1.6 1 0 0 1 1 1 0 Initiation control protein YabA LURAP PF14854.6 ORX97848.1 - 0.079 12.9 0.0 0.079 12.9 0.0 1.7 2 0 0 2 2 2 0 Leucine rich adaptor protein DUF5392 PF17370.2 ORX97848.1 - 0.16 12.1 1.9 0.47 10.5 1.5 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5392) NRBF2 PF08961.10 ORX97848.1 - 0.53 9.9 5.8 0.082 12.5 1.2 1.9 2 0 0 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator bZIP_2 PF07716.15 ORX97848.1 - 1.5 9.0 13.4 0.58 10.3 10.7 1.7 2 0 0 2 2 2 0 Basic region leucine zipper Arg_decarbox_C PF17944.1 ORX97849.1 - 0.096 13.3 0.9 0.2 12.2 0.1 2.0 2 1 0 2 2 2 0 Arginine decarboxylase C-terminal helical extension Lactonase PF10282.9 ORX97850.1 - 0.00027 20.3 0.1 0.0022 17.3 0.0 2.3 2 1 1 3 3 3 1 Lactonase, 7-bladed beta-propeller Peptidase_M14 PF00246.24 ORX97852.1 - 1.7e-39 136.4 1.5 2.5e-39 135.8 1.5 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase DUF3433 PF11915.8 ORX97853.1 - 8.5e-24 83.8 15.0 3.7e-19 69.0 1.5 3.3 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) LtrA PF06772.11 ORX97855.1 - 8.7e-23 81.1 16.0 8.7e-23 81.1 16.0 2.0 2 0 0 2 2 2 1 Bacterial low temperature requirement A protein (LtrA) HlyIII PF03006.20 ORX97855.1 - 4.1 7.1 29.1 0.19 11.4 5.1 3.3 2 1 1 3 3 3 0 Haemolysin-III related GH131_N PF18271.1 ORX97856.1 - 5e-58 196.8 0.0 6.5e-58 196.4 0.0 1.0 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain RAP1 PF07218.11 ORX97857.1 - 3 6.0 4.3 3.6 5.7 4.3 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF4107 PF13389.6 ORX97857.1 - 4.9 7.3 5.5 18 5.5 5.4 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF4107) MFS_1 PF07690.16 ORX97859.1 - 3.7e-40 138.0 40.8 1.1e-31 110.1 22.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORX97859.1 - 3.9e-13 49.1 3.7 3.9e-13 49.1 3.7 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.7 ORX97859.1 - 5.8e-05 22.1 8.3 0.00063 18.7 2.3 3.4 2 2 1 3 3 3 3 MFS_1 like family MFS_2 PF13347.6 ORX97859.1 - 0.00013 20.7 11.1 0.077 11.5 3.9 3.6 2 2 1 3 3 3 3 MFS/sugar transport protein LacY_symp PF01306.19 ORX97859.1 - 0.0041 15.9 1.9 0.17 10.6 0.2 2.4 2 1 0 2 2 2 2 LacY proton/sugar symporter TRI12 PF06609.13 ORX97859.1 - 0.01 14.3 0.6 0.016 13.7 0.6 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Folate_carrier PF01770.18 ORX97859.1 - 0.092 11.5 0.0 0.2 10.4 0.0 1.5 1 0 0 1 1 1 0 Reduced folate carrier DJ-1_PfpI PF01965.24 ORX97860.1 - 5.4e-18 65.3 0.0 7.6e-18 64.9 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family SKG6 PF08693.10 ORX97861.1 - 0.0031 16.9 0.2 0.0042 16.4 0.2 1.2 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Croc_4 PF17691.1 ORX97861.1 - 0.048 13.7 0.6 0.076 13.1 0.5 1.4 2 0 0 2 2 2 0 Contingent replication of cDNA 4 Aspzincin_M35 PF14521.6 ORX97862.1 - 0.00019 22.0 0.6 0.87 10.1 0.2 2.3 2 0 0 2 2 2 2 Lysine-specific metallo-endopeptidase HRXXH PF13933.6 ORX97862.1 - 0.00095 18.8 0.0 0.0016 18.1 0.0 1.4 1 0 0 1 1 1 1 Putative peptidase family Esterase PF00756.20 ORX97864.1 - 0.00026 20.7 0.2 0.0016 18.1 0.2 2.1 1 1 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.16 ORX97864.1 - 0.0004 20.3 0.1 0.0011 18.9 0.0 1.8 1 1 1 2 2 2 1 Phospholipase/Carboxylesterase Peptidase_S15 PF02129.18 ORX97864.1 - 0.0077 15.9 0.1 0.011 15.3 0.1 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Esterase_phd PF10503.9 ORX97864.1 - 0.0095 15.4 0.9 0.05 13.1 0.2 2.1 1 1 1 2 2 2 1 Esterase PHB depolymerase DLH PF01738.18 ORX97864.1 - 0.027 14.0 0.2 0.07 12.7 0.1 1.7 1 1 1 2 2 2 0 Dienelactone hydrolase family NUDIX PF00293.28 ORX97865.1 - 2e-11 44.0 0.1 7.3e-11 42.2 0.0 1.7 2 0 0 2 2 2 1 NUDIX domain Abhydrolase_1 PF00561.20 ORX97868.1 - 2.3e-11 43.9 0.0 2.5e-07 30.6 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORX97868.1 - 2.4e-09 38.1 0.0 3.4e-09 37.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORX97868.1 - 3.3e-06 26.6 0.0 0.024 13.9 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 ORX97868.1 - 0.00021 21.4 0.0 0.00064 19.8 0.0 1.8 2 0 0 2 2 2 1 TAP-like protein DLH PF01738.18 ORX97868.1 - 0.0017 18.0 0.0 0.036 13.6 0.0 2.1 2 0 0 2 2 2 1 Dienelactone hydrolase family FSH1 PF03959.13 ORX97868.1 - 0.0091 15.7 0.0 0.098 12.3 0.0 2.1 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Peptidase_S9 PF00326.21 ORX97868.1 - 0.031 13.8 0.0 0.17 11.3 0.0 2.0 2 0 0 2 2 2 0 Prolyl oligopeptidase family BAAT_C PF08840.11 ORX97868.1 - 0.14 12.1 0.0 2.5 8.0 0.0 2.1 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal PhoPQ_related PF10142.9 ORX97868.1 - 0.15 10.7 0.0 0.2 10.3 0.0 1.2 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein Zn_clus PF00172.18 ORX97869.1 - 2.9e-07 30.5 7.1 5.4e-07 29.6 7.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2HC5 PF06221.13 ORX97871.1 - 1.2e-23 82.8 6.8 1.9e-23 82.2 6.8 1.3 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type Pro_isomerase PF00160.21 ORX97872.1 - 8e-55 185.4 0.0 9.1e-55 185.3 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ADH_N PF08240.12 ORX97873.1 - 2.3e-26 91.8 0.1 4.1e-26 91.0 0.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORX97873.1 - 1.2e-07 31.7 0.1 2.4e-07 30.8 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.6 ORX97873.1 - 9.7e-06 25.4 0.2 9.7e-06 25.4 0.2 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-associated Glu_dehyd_C PF16912.5 ORX97873.1 - 0.00082 18.9 0.0 0.0049 16.4 0.0 1.9 2 0 0 2 2 2 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 ORX97873.1 - 0.0064 15.8 0.1 0.011 15.1 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 ORX97873.1 - 0.037 12.7 0.6 0.13 11.0 0.3 1.8 2 0 0 2 2 2 0 HI0933-like protein Ank_5 PF13857.6 ORX97901.1 - 3.2e-08 33.7 0.0 3.8e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 ORX97901.1 - 1.2e-05 25.8 0.0 0.0037 17.8 0.0 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 ORX97901.1 - 0.0057 17.1 0.0 0.25 11.9 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 ORX97901.1 - 0.0085 16.7 0.0 0.063 13.9 0.0 1.9 1 1 0 1 1 1 1 Ankyrin repeats (many copies) PRIMA1 PF16101.5 ORX97904.1 - 0.057 13.5 7.2 0.089 12.8 7.2 1.3 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 AAA_16 PF13191.6 ORX97905.1 - 8.1e-05 23.1 0.9 0.0025 18.2 0.2 3.5 2 1 0 2 2 2 1 AAA ATPase domain TPR_12 PF13424.6 ORX97905.1 - 0.0002 21.6 11.9 0.2 12.0 0.1 6.7 6 1 2 8 8 8 1 Tetratricopeptide repeat AAA PF00004.29 ORX97905.1 - 0.0052 17.2 0.0 0.032 14.6 0.0 2.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 ORX97905.1 - 0.0053 16.7 0.7 0.041 13.8 0.1 2.9 2 1 0 2 2 2 1 NACHT domain AAA_19 PF13245.6 ORX97905.1 - 0.027 14.8 0.5 0.18 12.1 0.0 2.7 2 1 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 ORX97905.1 - 0.1 12.5 0.3 0.62 10.0 0.0 2.4 2 0 0 2 2 2 0 NTPase AAA_22 PF13401.6 ORX97905.1 - 0.11 12.8 0.0 0.11 12.8 0.0 3.8 4 1 1 5 5 5 0 AAA domain DUF726 PF05277.12 ORX97906.1 - 3.5e-118 394.4 0.1 4.9e-118 394.0 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Cutinase PF01083.22 ORX97906.1 - 0.016 15.1 0.0 0.033 14.2 0.0 1.4 1 0 0 1 1 1 0 Cutinase Thioesterase PF00975.20 ORX97906.1 - 0.028 14.5 0.0 0.072 13.2 0.0 1.6 1 0 0 1 1 1 0 Thioesterase domain FliP PF00813.20 ORX97944.1 - 0.082 12.8 3.0 1.9 8.4 0.2 2.4 2 0 0 2 2 2 0 FliP family SBD PF17882.1 ORX97944.1 - 0.1 12.5 0.0 1.4 8.8 0.0 2.1 2 0 0 2 2 2 0 OAA-family lectin sugar binding domain AMPK1_CBM PF16561.5 ORX97946.1 - 1.2e-26 92.7 0.0 1.8e-26 92.2 0.0 1.3 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase AMPKBI PF04739.15 ORX97946.1 - 5.1e-25 87.6 1.5 1.8e-24 85.8 1.5 2.0 1 0 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interaction domain CBM53 PF16760.5 ORX97946.1 - 0.092 13.3 0.0 0.18 12.4 0.0 1.4 1 0 0 1 1 1 0 Starch/carbohydrate-binding module (family 53) DUF4695 PF15766.5 ORX97946.1 - 0.14 12.4 0.0 19 5.5 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4695) Peptidase_M22 PF00814.25 ORX97947.1 - 5.4e-83 278.8 0.0 6.8e-83 278.5 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family DUF3107 PF11305.8 ORX97947.1 - 0.056 13.7 0.0 0.19 12.0 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3107) Carbam_trans_N PF02543.15 ORX97947.1 - 0.1 12.3 0.0 1.3 8.6 0.0 2.0 2 0 0 2 2 2 0 Carbamoyltransferase N-terminus SET PF00856.28 ORX97948.1 - 9.6e-23 81.4 0.0 2.1e-22 80.3 0.0 1.6 1 0 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.11 ORX97948.1 - 2.5e-06 28.2 0.0 9e-06 26.4 0.0 1.9 2 0 0 2 2 2 1 Rubisco LSMT substrate-binding EPL1 PF10513.9 ORX97949.1 - 2.3e-24 86.6 0.2 2.3e-24 86.6 0.2 2.7 2 1 0 2 2 2 1 Enhancer of polycomb-like Zn_clus PF00172.18 ORX97950.1 - 1e-11 44.7 10.5 1.8e-11 44.0 10.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 ORX97950.1 - 0.0011 17.9 0.0 0.0016 17.3 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Patatin PF01734.22 ORX97951.1 - 3e-08 34.1 0.3 3.4e-07 30.6 0.3 2.2 1 1 0 1 1 1 1 Patatin-like phospholipase DUF3341 PF11821.8 ORX97952.1 - 0.33 10.6 2.6 0.4 10.3 0.4 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF3341) MAGE_N PF12440.8 ORX97952.1 - 4.6 8.0 6.0 2 9.1 2.3 2.3 2 0 0 2 2 2 0 Melanoma associated antigen family N terminal PAP2 PF01569.21 ORX97953.1 - 2.5e-28 98.6 1.7 6.9e-28 97.1 0.2 2.0 1 1 1 2 2 2 2 PAP2 superfamily DUF2339 PF10101.9 ORX97953.1 - 0.024 13.2 7.3 0.15 10.6 3.4 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2339) RseC_MucC PF04246.12 ORX97953.1 - 1 9.3 6.0 1.1 9.2 0.5 2.9 3 1 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC Nro1 PF12753.7 ORX97954.1 - 0.12 11.3 0.2 0.17 10.8 0.2 1.1 1 0 0 1 1 1 0 Nuclear pore complex subunit Nro1 Methyltransf_23 PF13489.6 ORX97955.1 - 3.1e-13 49.9 0.0 4.8e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORX97955.1 - 5.6e-07 30.2 0.0 5.9e-05 23.7 0.0 3.1 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORX97955.1 - 7e-07 29.2 0.0 0.00029 20.7 0.0 2.7 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_12 PF08242.12 ORX97955.1 - 1.5e-05 25.6 0.0 0.00029 21.5 0.0 2.5 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORX97955.1 - 0.00018 22.1 0.0 0.31 11.7 0.0 3.0 3 0 0 3 3 3 2 Methyltransferase domain FtsJ PF01728.19 ORX97955.1 - 0.00048 20.3 0.0 0.0036 17.4 0.0 2.1 2 0 0 2 2 2 1 FtsJ-like methyltransferase MTS PF05175.14 ORX97955.1 - 0.00056 19.5 1.1 0.00073 19.1 0.0 1.7 3 0 0 3 3 3 1 Methyltransferase small domain Methyltransf_2 PF00891.18 ORX97955.1 - 0.0042 16.4 0.0 0.0066 15.8 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain PrmA PF06325.13 ORX97955.1 - 0.005 16.3 0.0 0.079 12.3 0.0 2.1 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.17 ORX97955.1 - 0.0073 15.8 0.0 0.018 14.5 0.0 1.6 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_32 PF13679.6 ORX97955.1 - 0.14 12.1 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain HGTP_anticodon PF03129.20 ORX97956.1 - 1.4e-21 76.4 0.0 5.3e-21 74.6 0.0 2.1 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 ORX97956.1 - 1.4e-08 34.9 0.0 1.4e-07 31.7 0.0 2.2 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Brix PF04427.18 ORX97957.1 - 2.9e-23 83.0 0.0 4.6e-23 82.3 0.0 1.3 1 0 0 1 1 1 1 Brix domain BUD22 PF09073.10 ORX97957.1 - 0.0046 16.4 30.9 0.0063 15.9 30.9 1.1 1 0 0 1 1 1 1 BUD22 Nop14 PF04147.12 ORX97957.1 - 0.021 13.1 23.6 0.026 12.8 23.6 1.1 1 0 0 1 1 1 0 Nop14-like family RRN3 PF05327.11 ORX97957.1 - 0.33 9.5 8.6 0.49 8.9 8.6 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DNA_pol_phi PF04931.13 ORX97957.1 - 3.2 5.7 19.0 5.2 5.0 19.0 1.2 1 0 0 1 1 1 0 DNA polymerase phi CAF1 PF04857.20 ORX97958.1 - 2.4e-17 63.1 0.0 2.3e-07 30.3 0.0 2.4 2 0 0 2 2 2 2 CAF1 family ribonuclease NDUF_B12 PF08122.12 ORX97959.1 - 5.8e-23 80.7 0.5 8.9e-23 80.1 0.5 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family DUF5539 PF17693.1 ORX97959.1 - 0.042 13.5 0.0 0.044 13.5 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5539) PBD PF00786.28 ORX97961.1 - 0.084 13.2 0.1 0.23 11.8 0.1 1.8 1 0 0 1 1 1 0 P21-Rho-binding domain FAD_binding_3 PF01494.19 ORX97962.1 - 1.5e-07 31.0 3.6 1.6e-06 27.7 0.1 2.7 1 1 1 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 ORX97962.1 - 0.0098 16.1 0.0 0.029 14.6 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ORX97962.1 - 0.079 12.2 0.0 0.19 10.9 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase zf-RING_7 PF02591.15 ORX97964.1 - 0.03 14.5 0.2 0.2 11.9 0.0 2.4 2 0 0 2 2 2 0 C4-type zinc ribbon domain zf-C2H2_4 PF13894.6 ORX97964.1 - 0.044 14.6 0.4 0.27 12.2 0.4 2.5 1 0 0 1 1 1 0 C2H2-type zinc finger Zn_Tnp_IS1595 PF12760.7 ORX97964.1 - 0.2 11.7 3.3 0.46 10.5 3.3 1.6 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-C2H2 PF00096.26 ORX97964.1 - 0.26 11.8 2.1 0.71 10.4 0.3 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type Glycophorin_A PF01102.18 ORX97965.1 - 0.022 15.0 0.9 0.034 14.4 0.9 1.4 1 1 0 1 1 1 0 Glycophorin A DiS_P_DiS PF06750.13 ORX97965.1 - 0.025 14.7 0.1 0.065 13.4 0.1 1.6 1 1 0 1 1 1 0 Bacterial Peptidase A24 N-terminal domain FeoB_associated PF12669.7 ORX97965.1 - 0.12 12.8 0.2 0.31 11.5 0.2 1.7 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein Prominin PF05478.11 ORX97965.1 - 0.16 9.9 0.2 0.23 9.4 0.2 1.1 1 0 0 1 1 1 0 Prominin Pyocin_S PF06958.12 ORX97965.1 - 0.28 11.7 2.3 0.37 11.3 2.3 1.1 1 0 0 1 1 1 0 S-type Pyocin Mg_trans_NIPA PF05653.14 ORX97966.1 - 1.2e-62 211.7 1.8 1.9e-59 201.2 1.0 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 ORX97966.1 - 0.0066 16.6 0.5 0.0066 16.6 0.5 3.2 3 0 0 3 3 3 2 EamA-like transporter family CD20 PF04103.15 ORX97966.1 - 0.16 12.0 2.1 2 8.5 0.0 3.1 3 1 1 4 4 4 0 CD20-like family MIF4G_like PF09088.11 ORX97967.1 - 2.8e-75 252.3 0.1 4.4e-75 251.7 0.1 1.3 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.11 ORX97967.1 - 3.1e-68 230.1 0.1 3.1e-68 230.1 0.1 1.7 2 0 0 2 2 2 1 MIF4G like FACT-Spt16_Nlob PF14826.6 ORX97967.1 - 0.15 11.9 0.1 0.33 10.7 0.1 1.5 1 0 0 1 1 1 0 FACT complex subunit SPT16 N-terminal lobe domain DUF4156 PF13698.6 ORX98019.1 - 0.064 13.6 0.2 0.12 12.7 0.0 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4156) Dynein_IC2 PF11540.8 ORX98021.1 - 0.039 13.9 5.7 28 4.8 0.1 5.2 5 0 0 5 5 5 0 Cytoplasmic dynein 1 intermediate chain 2 Cluap1 PF10234.9 ORX98021.1 - 0.058 12.8 23.2 0.13 11.7 7.8 2.2 1 1 1 2 2 2 0 Clusterin-associated protein-1 CENP-F_leu_zip PF10473.9 ORX98021.1 - 0.067 13.2 29.2 0.29 11.2 6.9 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 COG2 PF06148.11 ORX98021.1 - 0.3 11.2 14.9 0.058 13.5 2.3 2.8 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 PKcGMP_CC PF16808.5 ORX98021.1 - 0.5 10.3 0.0 0.5 10.3 0.0 4.0 3 1 1 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF812 PF05667.11 ORX98021.1 - 0.56 9.0 24.7 0.84 8.4 24.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Filament PF00038.21 ORX98021.1 - 0.74 9.3 29.4 0.19 11.3 14.6 2.3 1 1 1 2 2 2 0 Intermediate filament protein Spc7 PF08317.11 ORX98021.1 - 1 8.2 32.6 0.8 8.5 14.9 2.1 1 1 0 2 2 2 0 Spc7 kinetochore protein DUF1664 PF07889.12 ORX98021.1 - 1.2 9.1 14.9 0.69 10.0 2.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) FliJ PF02050.16 ORX98021.1 - 2.1 8.6 33.4 4.9 7.4 12.3 2.3 2 0 0 2 2 2 0 Flagellar FliJ protein DUF2353 PF09789.9 ORX98021.1 - 2.9 7.2 24.7 5 6.4 24.7 1.3 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) DUF641 PF04859.12 ORX98021.1 - 6 7.2 18.5 2.1 8.7 6.8 2.7 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) HOOK PF05622.12 ORX98021.1 - 7.4 4.6 32.3 2.3 6.3 3.7 2.1 1 1 1 2 2 2 0 HOOK protein CENP-H PF05837.12 ORX98021.1 - 7.9 6.9 22.9 6.3 7.2 6.4 2.4 2 0 0 2 2 2 0 Centromere protein H (CENP-H) RR_TM4-6 PF06459.12 ORX98022.1 - 1 9.1 27.4 1.6 8.5 27.4 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4569 PF15133.6 ORX98022.1 - 7.3 6.2 13.9 15 5.2 13.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) SAPS PF04499.15 ORX98022.1 - 9.2 4.9 11.0 15 4.2 11.0 1.4 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein MscL PF01741.18 ORX98025.1 - 3.4e-19 69.3 0.1 4.4e-19 69.0 0.1 1.1 1 0 0 1 1 1 1 Large-conductance mechanosensitive channel, MscL C1_1 PF00130.22 ORX98025.1 - 0.065 13.1 1.8 0.11 12.4 1.8 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zinc_ribbon_2 PF13240.6 ORX98025.1 - 1.2 8.9 4.4 2.3 8.1 4.4 1.4 1 0 0 1 1 1 0 zinc-ribbon domain AAA PF00004.29 ORX98026.1 - 9.3e-11 42.3 0.0 1.9e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 ORX98026.1 - 0.11 11.8 0.8 0.37 10.1 0.1 1.9 2 0 0 2 2 2 0 KaiC DUF4360 PF14273.6 ORX98027.1 - 4.5e-66 222.1 6.7 5.6e-66 221.8 6.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Velvet PF11754.8 ORX98028.1 - 0.00022 21.3 0.0 0.00032 20.7 0.0 1.3 1 1 0 1 1 1 1 Velvet factor Glyco_transf_90 PF05686.12 ORX98030.1 - 3.2e-12 46.1 7.1 6.1e-09 35.3 2.3 3.5 2 1 0 2 2 2 2 Glycosyl transferase family 90 tRNA-synt_1d PF00750.19 ORX98031.1 - 1.1e-98 330.5 9.7 4.3e-97 325.2 9.7 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 ORX98031.1 - 6.7e-28 97.3 1.1 2.7e-27 95.3 0.2 2.3 2 0 0 2 2 2 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 ORX98031.1 - 6.9e-05 23.4 0.0 0.00017 22.1 0.0 1.7 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain DUF4393 PF14337.6 ORX98031.1 - 0.13 12.0 0.5 0.22 11.3 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4393) DUF148 PF02520.17 ORX98031.1 - 0.2 11.8 1.2 2.4 8.3 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF148 IMS PF00817.20 ORX98034.1 - 2.6e-39 134.6 0.0 4.5e-39 133.8 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family zf_UBZ PF18439.1 ORX98034.1 - 1.7e-13 49.9 0.9 3.4e-13 48.9 0.9 1.5 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger IMS_C PF11799.8 ORX98034.1 - 2.1e-09 38.1 0.0 1.3e-08 35.6 0.0 2.3 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 ORX98034.1 - 0.009 16.3 0.0 0.032 14.6 0.0 2.0 1 0 0 1 1 1 1 IMS family HHH motif zf-CCCH_6 PF18585.1 ORX98035.1 - 0.096 12.6 5.8 0.32 10.9 2.6 2.4 2 0 0 2 2 2 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 NDUF_B12 PF08122.12 ORX98035.1 - 0.13 12.3 0.4 0.13 12.3 0.4 2.0 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B12 subunit family Fez1 PF06818.15 ORX98037.1 - 0.003 18.0 0.7 0.0034 17.9 0.7 1.1 1 0 0 1 1 1 1 Fez1 Oberon_cc PF16312.5 ORX98037.1 - 0.0033 17.3 2.4 0.0042 17.0 2.4 1.1 1 0 0 1 1 1 1 Coiled-coil region of Oberon PV-1 PF06637.11 ORX98037.1 - 0.081 11.7 0.5 0.098 11.5 0.5 1.1 1 0 0 1 1 1 0 PV-1 protein (PLVAP) HET PF06985.11 ORX98068.1 - 5.1e-20 72.3 0.0 6.1e-20 72.1 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Nucleolin_bd PF16725.5 ORX98069.1 - 0.027 14.1 0.0 4.8 6.9 0.0 2.8 3 0 0 3 3 3 0 Nucleolin binding domain HET PF06985.11 ORX98069.1 - 0.092 13.1 0.2 0.15 12.4 0.2 1.4 1 0 0 1 1 1 0 Heterokaryon incompatibility protein (HET) Acetyltransf_3 PF13302.7 ORX98070.1 - 1.1e-12 48.9 0.0 1.6e-12 48.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Peptidase_S68 PF10461.9 ORX98072.1 - 0.15 12.3 0.0 0.26 11.5 0.0 1.4 1 0 0 1 1 1 0 Peptidase S68 Tuberculin PF12198.8 ORX98073.1 - 0.17 12.0 0.1 0.3 11.2 0.1 1.3 1 0 0 1 1 1 0 Theoretical tuberculin protein Mitochondr_Som1 PF11093.8 ORX98076.1 - 1.4e-05 24.9 1.2 2.8e-05 24.0 1.2 1.6 1 0 0 1 1 1 1 Mitochondrial export protein Som1 DEC-1_N PF04625.13 ORX98076.1 - 9.8 5.1 12.0 16 4.4 12.0 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region WD40 PF00400.32 ORX98078.1 - 1.8e-107 348.2 65.3 7.7e-11 42.4 0.4 12.7 11 1 1 12 12 12 12 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX98078.1 - 1.2e-31 108.8 22.1 0.00039 20.7 0.2 9.9 1 1 9 10 10 10 10 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ORX98078.1 - 4.9e-19 68.4 29.1 0.096 11.3 0.2 10.0 1 1 9 10 10 10 9 Nucleoporin Nup120/160 CDtoxinA PF03498.14 ORX98078.1 - 6.6e-13 48.5 0.6 0.24 11.0 0.0 6.0 1 1 5 6 6 6 5 Cytolethal distending toxin A/C domain NACHT PF05729.12 ORX98078.1 - 1.5e-12 47.8 0.2 2.9e-12 46.8 0.2 1.4 1 0 0 1 1 1 1 NACHT domain Ge1_WD40 PF16529.5 ORX98078.1 - 9e-11 41.3 31.8 0.023 13.6 4.0 7.2 1 1 5 6 6 6 6 WD40 region of Ge1, enhancer of mRNA-decapping protein Ricin_B_lectin PF00652.22 ORX98078.1 - 2.1e-06 28.0 11.8 0.036 14.3 0.5 4.5 2 2 3 5 5 5 3 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 ORX98078.1 - 4.3e-06 27.4 14.0 3.1 8.6 0.3 6.1 3 1 3 6 6 6 3 Ricin-type beta-trefoil lectin domain-like WD40_like PF17005.5 ORX98078.1 - 1.8e-05 24.3 0.3 9.2 5.5 0.0 4.4 1 1 0 4 4 4 1 WD40-like domain Cytochrom_D1 PF02239.16 ORX98078.1 - 0.0036 15.9 4.7 2.7 6.4 0.1 3.9 1 1 2 4 4 4 2 Cytochrome D1 heme domain HTH_Bact PF18768.1 ORX98078.1 - 0.049 13.2 0.1 36 4.0 0.0 4.0 4 0 0 4 4 4 0 Helix-turn-helix bacterial domain TPR_10 PF13374.6 ORX98079.1 - 2.7e-106 345.0 35.8 1.3e-13 50.3 0.1 13.2 12 1 1 13 13 13 12 Tetratricopeptide repeat TPR_12 PF13424.6 ORX98079.1 - 3.4e-74 245.1 27.9 1.3e-13 51.1 0.8 9.9 2 2 9 11 11 11 11 Tetratricopeptide repeat TPR_7 PF13176.6 ORX98079.1 - 3.8e-31 104.8 17.7 0.018 15.0 0.0 11.8 12 0 0 12 12 12 8 Tetratricopeptide repeat TPR_2 PF07719.17 ORX98079.1 - 8.1e-16 56.8 12.5 0.72 10.1 0.0 9.5 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_17 PF13431.6 ORX98079.1 - 3.7e-15 55.1 14.1 0.25 11.8 0.1 9.8 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_4 PF07721.14 ORX98079.1 - 1.6e-13 49.9 2.6 0.84 10.5 0.0 8.1 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_1 PF00515.28 ORX98079.1 - 7.3e-11 41.4 4.0 0.99 9.3 0.0 7.7 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 ORX98079.1 - 6.1e-09 36.3 2.8 5.7 7.5 0.1 7.4 5 1 2 7 7 7 1 Tetratricopeptide repeat TPR_8 PF13181.6 ORX98079.1 - 3.3e-06 26.9 10.6 0.3 11.4 0.1 7.8 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_16 PF13432.6 ORX98079.1 - 5.5e-06 26.9 1.8 28 5.5 0.0 6.3 7 0 0 7 7 7 0 Tetratricopeptide repeat AlaDh_PNT_N PF05222.15 ORX98079.1 - 0.011 16.0 8.9 1 9.6 0.1 5.2 5 2 1 6 6 6 0 Alanine dehydrogenase/PNT, N-terminal domain ANAPC3 PF12895.7 ORX98079.1 - 0.012 15.8 0.7 36 4.7 0.0 4.8 3 2 1 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 Putative_G5P PF17426.2 ORX98079.1 - 0.034 14.2 0.1 97 3.1 0.0 4.5 5 1 1 6 6 5 0 Putative Gamma DNA binding protein G5P DUF4119 PF13494.6 ORX98079.1 - 0.17 12.0 10.3 9.9 6.4 0.0 5.5 2 1 0 5 5 5 0 Domain of unknown function, B. Theta Gene description (DUF4119) PIN_9 PF18477.1 ORX98079.1 - 0.52 10.6 4.2 13 6.2 0.5 4.2 1 1 1 4 4 4 0 PIN like domain cwf21 PF08312.12 ORX98079.1 - 0.88 9.8 23.0 0.55 10.4 0.2 4.6 1 1 3 4 4 4 0 cwf21 domain TPR_14 PF13428.6 ORX98079.1 - 1.8 9.6 15.8 77 4.5 0.0 6.9 8 0 0 8 8 7 0 Tetratricopeptide repeat PALP PF00291.25 ORX98081.1 - 1.1e-78 264.7 0.3 1.3e-78 264.4 0.3 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 ORX98081.1 - 8.9e-42 140.8 0.0 1.3e-19 69.7 0.0 2.3 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase PRR18 PF15671.5 ORX98082.1 - 0.055 13.4 0.2 0.1 12.5 0.2 1.4 1 0 0 1 1 1 0 Proline-rich protein family 18 NGP1NT PF08153.12 ORX98089.1 - 1.2e-45 154.9 0.7 1.8e-45 154.3 0.7 1.3 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 ORX98089.1 - 6e-18 65.0 0.0 1.2e-13 51.1 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 ORX98089.1 - 6.8e-07 28.9 0.0 8e-06 25.5 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 ORX98089.1 - 0.00015 21.8 0.1 0.63 10.1 0.0 3.5 2 1 1 3 3 3 1 Dynamin family RsgA_GTPase PF03193.16 ORX98089.1 - 0.00036 20.5 0.0 0.0011 18.9 0.0 1.8 1 1 0 1 1 1 1 RsgA GTPase GTP_EFTU PF00009.27 ORX98089.1 - 0.0033 17.0 0.1 0.21 11.1 0.0 2.9 1 1 2 3 3 3 1 Elongation factor Tu GTP binding domain Arf PF00025.21 ORX98089.1 - 0.0038 16.7 0.1 0.19 11.1 0.0 2.3 2 0 0 2 2 2 1 ADP-ribosylation factor family AAA_18 PF13238.6 ORX98089.1 - 0.1 13.2 0.1 0.5 10.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain BTB PF00651.31 ORX98105.1 - 0.0035 17.6 0.1 0.0082 16.4 0.0 1.6 2 0 0 2 2 2 1 BTB/POZ domain Rx_N PF18052.1 ORX98105.1 - 0.026 14.8 0.0 0.34 11.2 0.0 2.8 2 1 1 4 4 4 0 Rx N-terminal domain MnmE_helical PF12631.7 ORX98105.1 - 0.13 12.4 0.9 0.2 11.8 0.9 1.3 1 0 0 1 1 1 0 MnmE helical domain CSTF2_hinge PF14327.6 ORX98105.1 - 0.26 11.8 1.4 0.62 10.6 1.4 1.6 1 0 0 1 1 1 0 Hinge domain of cleavage stimulation factor subunit 2 Pkinase PF00069.25 ORX98106.1 - 1.4e-32 113.1 0.0 2.3e-32 112.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Rad4 PF03835.15 ORX98106.1 - 2.4e-31 108.4 0.2 9.2e-31 106.5 0.0 2.2 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain BHD_3 PF10405.9 ORX98106.1 - 4.4e-28 97.5 0.6 8.2e-28 96.6 0.1 1.8 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 3 Pkinase_Tyr PF07714.17 ORX98106.1 - 7.7e-21 74.5 0.0 1.8e-20 73.3 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase BHD_1 PF10403.9 ORX98106.1 - 1.4e-16 60.1 0.1 3.7e-16 58.7 0.1 1.8 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 ORX98106.1 - 9.2e-15 55.4 1.9 9.2e-15 55.4 1.9 3.4 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.19 ORX98106.1 - 0.027 14.9 0.0 0.08 13.4 0.0 1.8 1 0 0 1 1 1 0 Transglutaminase-like superfamily zf-C2H2_4 PF13894.6 ORX98107.1 - 3.4e-09 36.8 22.1 0.003 18.3 1.4 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.26 ORX98107.1 - 2.2e-07 30.9 31.7 0.00011 22.5 2.6 4.2 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORX98107.1 - 0.0018 18.6 23.4 0.0055 17.1 4.3 4.5 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_6 PF13912.6 ORX98107.1 - 0.032 14.2 0.7 0.032 14.2 0.7 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger zinc_ribbon_9 PF14369.6 ORX98107.1 - 0.84 10.0 7.7 0.49 10.7 0.7 2.7 2 0 0 2 2 2 0 zinc-ribbon zf-met PF12874.7 ORX98107.1 - 1.4 9.4 0.0 1.4 9.4 0.0 3.4 4 0 0 4 4 4 0 Zinc-finger of C2H2 type NAGLU PF05089.12 ORX98108.1 - 6.3e-132 439.6 6.4 1.1e-131 438.8 6.4 1.4 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain NAGLU_C PF12972.7 ORX98108.1 - 8.9e-64 215.6 1.3 4.5e-63 213.3 0.8 2.0 2 0 0 2 2 2 1 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain NAGLU_N PF12971.7 ORX98108.1 - 2.2e-16 59.4 0.0 4.9e-16 58.3 0.0 1.6 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain Cyclin PF08613.11 ORX98110.1 - 1.5e-25 90.4 0.0 3.3e-25 89.3 0.0 1.4 2 0 0 2 2 2 1 Cyclin KRE9 PF05390.11 ORX98111.1 - 1.5e-18 67.4 4.4 1.5e-18 67.4 4.4 2.1 3 0 0 3 3 3 1 Yeast cell wall synthesis protein KRE9/KNH1 GPI-anchored PF10342.9 ORX98111.1 - 1.8e-14 54.2 1.3 6.7e-14 52.4 0.1 2.3 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF5034 PF16437.5 ORX98111.1 - 0.15 12.1 0.0 5.9 6.9 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF5034) Big_7 PF17957.1 ORX98111.1 - 0.24 12.2 5.1 0.14 12.9 1.2 2.7 2 1 0 2 2 2 0 Bacterial Ig domain Peptidase_M24 PF00557.24 ORX98112.1 - 8.7e-57 192.2 0.0 1.2e-56 191.8 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 ORX98112.1 - 1.9e-26 92.2 0.0 3.2e-26 91.5 0.0 1.3 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain DUF5497 PF17601.2 ORX98112.1 - 0.073 13.4 0.1 0.24 11.7 0.1 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5497) Glyco_hydro_61 PF03443.14 ORX98113.1 - 1e-58 198.7 0.7 1.4e-58 198.2 0.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.18 ORX98113.1 - 1.4e-09 37.7 11.2 1.4e-09 37.7 11.2 2.4 2 0 0 2 2 2 1 Fungal cellulose binding domain Acetyltransf_1 PF00583.25 ORX98115.1 - 5.2e-11 42.8 0.0 7.7e-11 42.3 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ORX98115.1 - 3.3e-09 36.8 0.0 4.7e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ORX98115.1 - 5.9e-08 33.0 0.0 9.2e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 ORX98115.1 - 0.0012 19.0 0.0 0.0018 18.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 ORX98115.1 - 0.003 17.6 0.0 0.006 16.7 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 ORX98115.1 - 0.015 15.3 0.0 0.029 14.4 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_9 PF13527.7 ORX98115.1 - 0.072 13.2 0.0 0.23 11.5 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain ubiquitin PF00240.23 ORX98117.1 - 1.5e-10 40.7 0.0 2.6e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family YukD PF08817.10 ORX98117.1 - 0.0086 16.8 0.6 0.21 12.3 0.0 2.8 2 1 0 2 2 2 1 WXG100 protein secretion system (Wss), protein YukD Rad60-SLD PF11976.8 ORX98117.1 - 0.043 13.6 0.0 0.13 12.1 0.0 1.8 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like UN_NPL4 PF11543.8 ORX98117.1 - 0.057 13.9 0.0 0.1 13.1 0.0 1.4 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Methyltransf_8 PF05148.15 ORX98118.1 - 2.3e-52 178.0 0.1 1.2e-49 169.1 0.0 3.5 3 1 0 3 3 3 1 Hypothetical methyltransferase Methyltransf_11 PF08241.12 ORX98118.1 - 6.4e-08 33.1 0.0 3.4e-07 30.8 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORX98118.1 - 1.4e-05 25.7 0.0 0.00022 21.9 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORX98118.1 - 0.00018 21.4 0.0 0.057 13.2 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain MTS PF05175.14 ORX98118.1 - 0.046 13.3 0.0 3.4 7.2 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_32 PF13679.6 ORX98118.1 - 0.049 13.6 0.0 0.049 13.6 0.0 2.7 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.12 ORX98118.1 - 1 10.1 0.0 1 10.1 0.0 3.3 5 1 0 5 5 5 0 Methyltransferase domain DUF3982 PF13138.6 ORX98119.1 - 0.35 10.7 1.0 0.55 10.1 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3982) Ank_2 PF12796.7 ORX98120.1 - 2.1e-12 47.4 0.0 7.4e-09 36.1 0.1 2.5 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 ORX98120.1 - 3.1e-09 36.9 0.3 1 9.9 0.0 4.7 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.6 ORX98120.1 - 6.2e-09 36.2 0.1 0.0065 17.0 0.0 4.1 2 2 2 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORX98120.1 - 2e-08 33.8 0.0 0.3 11.8 0.0 4.6 4 1 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 ORX98120.1 - 6.7e-05 23.1 0.1 0.013 15.8 0.0 3.9 3 1 1 4 4 4 2 Ankyrin repeats (many copies) GFA PF04828.14 ORX98122.1 - 4.8e-07 30.0 0.4 4.8e-07 30.0 0.4 1.8 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme PAP2_3 PF14378.6 ORX98124.1 - 1.2e-24 87.1 15.3 1.1e-20 74.1 4.0 2.4 2 0 0 2 2 2 2 PAP2 superfamily PAP2 PF01569.21 ORX98124.1 - 1.2 8.9 11.3 0.64 9.8 8.3 2.0 1 1 1 2 2 2 0 PAP2 superfamily BTB PF00651.31 ORX98125.1 - 8.7e-05 22.7 0.0 0.0016 18.6 0.0 2.3 2 0 0 2 2 2 1 BTB/POZ domain Rot1 PF10681.9 ORX98126.1 - 2.5e-95 317.9 0.2 2.9e-95 317.7 0.2 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal 5-FTHF_cyc-lig PF01812.20 ORX98127.1 - 2.4e-34 118.8 0.0 1.5e-33 116.2 0.0 1.8 1 1 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family LSM PF01423.22 ORX98128.1 - 1.1e-16 60.2 0.1 1.3e-16 60.0 0.1 1.1 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 ORX98128.1 - 0.0048 16.5 0.0 0.0073 15.9 0.0 1.3 1 0 0 1 1 1 1 Hfq protein Xpo1 PF08389.12 ORX98129.1 - 1.1e-27 96.9 0.4 1.3e-26 93.4 0.3 2.8 2 0 0 2 2 2 1 Exportin 1-like protein IBN_N PF03810.19 ORX98129.1 - 6e-08 32.5 0.0 3.1e-07 30.2 0.0 2.3 2 0 0 2 2 2 1 Importin-beta N-terminal domain HEAT_EZ PF13513.6 ORX98129.1 - 8.2e-06 26.2 1.1 0.00011 22.6 0.0 3.6 4 0 0 4 4 4 1 HEAT-like repeat HEAT_2 PF13646.6 ORX98129.1 - 0.00043 20.6 0.1 0.0034 17.7 0.0 2.7 2 0 0 2 2 2 1 HEAT repeats HEAT PF02985.22 ORX98129.1 - 0.069 13.4 0.4 74 4.0 0.0 4.1 3 0 0 3 3 3 0 HEAT repeat Adaptin_N PF01602.20 ORX98129.1 - 0.098 11.2 0.3 0.61 8.6 0.1 2.1 2 0 0 2 2 2 0 Adaptin N terminal region MaoC_dehydratas PF01575.19 ORX98170.1 - 0.0018 17.8 0.0 0.0033 17.0 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain PDT PF00800.18 ORX98171.1 - 1.1e-54 185.0 0.0 2.3e-54 184.0 0.0 1.5 1 1 0 1 1 1 1 Prephenate dehydratase ACT PF01842.25 ORX98171.1 - 6.2e-06 25.9 0.1 2e-05 24.3 0.0 1.9 2 0 0 2 2 2 1 ACT domain eRF1_2 PF03464.15 ORX98172.1 - 3.9e-47 159.9 0.1 6.2e-47 159.2 0.1 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 ORX98172.1 - 1e-39 135.5 0.5 2.2e-39 134.5 0.5 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 ORX98172.1 - 4.9e-21 75.1 0.0 7.9e-21 74.4 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 baeRF_family10 PF18854.1 ORX98172.1 - 1.2e-09 38.5 0.0 2.1e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 acVLRF1 PF18859.1 ORX98172.1 - 8.3e-09 35.8 0.0 1.3e-08 35.2 0.0 1.3 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor Rad50_zn_hook PF04423.14 ORX98172.1 - 0.045 13.6 0.9 6.8 6.6 0.1 3.1 3 0 0 3 3 3 0 Rad50 zinc hook motif DUF4825 PF16107.5 ORX98172.1 - 0.046 13.9 0.0 3.5 7.8 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4825) Aa_trans PF01490.18 ORX98173.1 - 5.9e-65 219.6 28.3 7.2e-65 219.3 28.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein zf-Tim10_DDP PF02953.15 ORX98174.1 - 3.3e-22 77.9 0.1 4.2e-22 77.6 0.1 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF228 PF02989.14 ORX98174.1 - 0.081 12.7 0.0 0.1 12.4 0.0 1.1 1 0 0 1 1 1 0 Lyme disease proteins of unknown function PAZ_siRNAbind PF12212.8 ORX98174.1 - 0.13 12.1 0.0 0.16 11.8 0.0 1.1 1 0 0 1 1 1 0 PAZ domain Ribosomal_L23eN PF03939.13 ORX98175.1 - 1.8e-25 88.9 7.7 4e-25 87.8 7.7 1.6 1 0 0 1 1 1 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 ORX98175.1 - 2.2e-14 53.6 0.6 2.2e-14 53.6 0.6 1.6 2 0 0 2 2 2 1 Ribosomal protein L23 TusA PF01206.17 ORX98175.1 - 0.076 12.9 0.1 0.14 12.0 0.1 1.4 1 0 0 1 1 1 0 Sulfurtransferase TusA Bmt2 PF11968.8 ORX98176.1 - 1e-83 280.5 0.0 1.3e-83 280.2 0.0 1.1 1 0 0 1 1 1 1 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 zf-H3C2 PF16721.5 ORX98177.1 - 0.12 12.7 0.0 0.28 11.6 0.0 1.7 1 1 0 1 1 1 0 Zinc-finger like, probable DNA-binding TPR_12 PF13424.6 ORX98178.1 - 1.1e-25 89.7 3.3 1.4e-10 41.3 0.2 5.7 3 2 2 6 6 5 4 Tetratricopeptide repeat NB-ARC PF00931.22 ORX98178.1 - 3.7e-15 55.8 0.0 6.7e-15 55.0 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain TPR_10 PF13374.6 ORX98178.1 - 5.7e-12 45.1 14.0 0.0074 16.1 1.2 6.8 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 ORX98178.1 - 3.4e-10 39.3 3.3 0.00028 20.6 0.4 5.4 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 ORX98178.1 - 6.2e-09 35.4 2.1 0.11 12.7 0.0 5.6 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 ORX98178.1 - 7.2e-09 35.1 7.5 0.55 10.4 0.1 7.2 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_MalT PF17874.1 ORX98178.1 - 1.4e-07 31.3 0.3 6e-06 25.9 0.2 2.9 2 1 0 2 2 2 1 MalT-like TPR region TPR_14 PF13428.6 ORX98178.1 - 1.7e-06 28.3 10.1 4.2 8.4 0.0 6.5 7 0 0 7 7 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 ORX98178.1 - 2.7e-06 27.1 9.4 8.5 6.8 0.0 7.6 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_19 PF14559.6 ORX98178.1 - 7.4e-06 26.4 3.2 0.21 12.2 0.1 5.4 5 1 1 6 6 6 1 Tetratricopeptide repeat AAA_16 PF13191.6 ORX98178.1 - 5.8e-05 23.5 0.0 0.0003 21.2 0.0 2.3 1 0 0 1 1 1 1 AAA ATPase domain TPR_16 PF13432.6 ORX98178.1 - 0.00098 19.7 5.6 9 7.0 0.1 5.3 6 0 0 6 6 5 1 Tetratricopeptide repeat PPR PF01535.20 ORX98178.1 - 0.0016 18.6 0.4 0.14 12.4 0.0 3.9 3 0 0 3 3 3 1 PPR repeat TPR_6 PF13174.6 ORX98178.1 - 0.003 18.1 1.9 7.3 7.5 0.0 5.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_4 PF07721.14 ORX98178.1 - 0.0056 17.2 0.0 17 6.4 0.0 4.5 4 0 0 4 4 3 0 Tetratricopeptide repeat ArsA_ATPase PF02374.15 ORX98178.1 - 0.026 13.7 0.0 0.049 12.8 0.0 1.4 1 0 0 1 1 1 0 Anion-transporting ATPase DUF5100 PF17029.5 ORX98178.1 - 0.11 12.3 0.1 4.6 7.1 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF5100) TPR_17 PF13431.6 ORX98178.1 - 0.14 12.6 0.1 40 4.9 0.0 3.8 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 ORX98178.1 - 0.84 9.4 2.5 9.5 6.0 0.5 3.4 3 0 0 3 3 3 0 TPR repeat Peptidase_M49 PF03571.15 ORX98180.1 - 2.9e-210 699.3 0.0 3.3e-210 699.1 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M49 APH PF01636.23 ORX98181.1 - 1.5e-17 64.4 0.0 5.3e-17 62.6 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 ORX98181.1 - 7.2e-07 28.8 0.0 1.1e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.11 ORX98181.1 - 0.00018 20.5 0.0 0.00027 19.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) Choline_kinase PF01633.20 ORX98181.1 - 0.00083 19.0 0.0 0.0023 17.6 0.0 1.7 1 1 0 1 1 1 1 Choline/ethanolamine kinase Fructosamin_kin PF03881.14 ORX98181.1 - 0.029 13.6 0.0 0.86 8.7 0.0 2.2 2 0 0 2 2 2 0 Fructosamine kinase Abhydrolase_1 PF00561.20 ORX98182.1 - 9e-25 87.8 0.0 8.6e-24 84.6 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORX98182.1 - 1e-16 62.2 0.0 1.7e-16 61.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORX98182.1 - 4.1e-11 42.6 0.0 5.7e-11 42.1 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 ORX98182.1 - 5.5e-07 29.5 0.1 0.00016 21.5 0.1 2.2 1 1 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.20 ORX98182.1 - 9.9e-05 22.6 0.0 0.00016 21.9 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain DUF676 PF05057.14 ORX98182.1 - 0.0019 17.8 0.0 0.0028 17.2 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) LCAT PF02450.15 ORX98182.1 - 0.0045 16.2 0.0 0.0066 15.7 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF915 PF06028.11 ORX98182.1 - 0.0072 15.7 0.1 1.6 8.0 0.0 2.3 1 1 0 2 2 2 2 Alpha/beta hydrolase of unknown function (DUF915) BAAT_C PF08840.11 ORX98182.1 - 0.0077 16.2 0.0 0.012 15.6 0.0 1.2 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Chlorophyllase2 PF12740.7 ORX98182.1 - 0.011 14.7 0.1 0.018 14.0 0.1 1.5 1 1 0 1 1 1 0 Chlorophyllase enzyme Palm_thioest PF02089.15 ORX98182.1 - 0.016 15.0 0.0 0.023 14.6 0.0 1.1 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Ndr PF03096.14 ORX98182.1 - 0.037 12.7 0.0 0.066 11.9 0.0 1.4 1 0 0 1 1 1 0 Ndr family DUF900 PF05990.12 ORX98182.1 - 0.055 13.0 0.1 0.099 12.1 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Esterase PF00756.20 ORX98182.1 - 0.15 11.6 0.0 0.22 11.1 0.0 1.4 1 1 0 1 1 1 0 Putative esterase Astacin PF01400.24 ORX98183.1 - 2e-15 56.9 0.2 7.3e-11 42.0 0.1 2.3 2 0 0 2 2 2 2 Astacin (Peptidase family M12A) TPR_12 PF13424.6 ORX98184.1 - 3.1e-44 149.2 4.2 8.5e-14 51.6 0.1 4.6 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.6 ORX98184.1 - 7.9e-43 143.2 7.8 6.3e-11 41.8 0.1 6.0 6 0 0 6 6 5 4 Tetratricopeptide repeat Patatin PF01734.22 ORX98184.1 - 1.9e-18 67.4 0.1 2.4e-08 34.4 0.0 2.7 1 1 0 2 2 2 2 Patatin-like phospholipase TPR_7 PF13176.6 ORX98184.1 - 3.6e-12 45.4 0.0 0.00026 20.8 0.0 5.0 5 0 0 5 5 4 2 Tetratricopeptide repeat NB-ARC PF00931.22 ORX98184.1 - 1.3e-09 37.6 0.0 2.5e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain TPR_2 PF07719.17 ORX98184.1 - 1.9e-09 36.9 0.0 1.9 8.8 0.0 5.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 ORX98184.1 - 2.8e-09 36.5 0.4 0.062 13.5 0.0 5.5 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_MalT PF17874.1 ORX98184.1 - 1.1e-07 31.5 0.3 2e-07 30.7 0.3 1.3 1 0 0 1 1 1 1 MalT-like TPR region TPR_17 PF13431.6 ORX98184.1 - 1.6e-05 24.9 0.4 0.74 10.3 0.1 5.0 5 0 0 5 5 4 1 Tetratricopeptide repeat ATPase_2 PF01637.18 ORX98184.1 - 2.2e-05 24.5 0.1 0.00013 22.0 0.0 2.2 3 0 0 3 3 3 1 ATPase domain predominantly from Archaea NACHT PF05729.12 ORX98184.1 - 2.9e-05 24.0 0.0 6.1e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 NACHT domain TPR_4 PF07721.14 ORX98184.1 - 9.6e-05 22.7 0.0 4.6 8.2 0.1 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat AAA_16 PF13191.6 ORX98184.1 - 0.0002 21.8 0.2 0.0008 19.8 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain TPR_19 PF14559.6 ORX98184.1 - 0.00036 21.0 0.2 0.22 12.0 0.1 3.7 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 ORX98184.1 - 0.00049 20.7 0.0 2 9.1 0.5 4.3 2 1 3 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 ORX98184.1 - 0.00078 19.2 0.1 1.1 9.2 0.0 4.2 5 0 0 5 5 5 1 Tetratricopeptide repeat AAA_22 PF13401.6 ORX98184.1 - 0.007 16.6 0.0 0.2 11.9 0.0 2.6 1 1 0 1 1 1 1 AAA domain TPR_14 PF13428.6 ORX98184.1 - 0.0081 16.9 0.0 3.7 8.6 0.0 4.7 7 0 0 7 7 2 1 Tetratricopeptide repeat SNAP PF14938.6 ORX98184.1 - 0.11 11.9 0.1 0.38 10.1 0.0 1.7 1 1 1 2 2 2 0 Soluble NSF attachment protein, SNAP TPR_6 PF13174.6 ORX98184.1 - 0.76 10.6 3.2 44 5.0 0.1 4.4 5 0 0 5 5 4 0 Tetratricopeptide repeat DUF2310 PF10071.9 ORX98185.1 - 0.043 13.1 0.0 0.055 12.7 0.0 1.1 1 0 0 1 1 1 0 Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310) Ank_2 PF12796.7 ORX98186.1 - 7.4e-13 48.9 0.0 8.3e-07 29.5 0.0 4.4 2 1 1 4 4 4 3 Ankyrin repeats (3 copies) NACHT PF05729.12 ORX98186.1 - 1.9e-11 44.1 0.9 1.2e-10 41.5 0.3 2.3 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 ORX98186.1 - 4.3e-11 43.5 0.7 3e-10 40.8 0.1 2.7 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 ORX98186.1 - 2.4e-09 37.6 0.2 8.2e-09 35.9 0.2 2.0 1 0 0 1 1 1 1 AAA domain Ank_5 PF13857.6 ORX98186.1 - 3.3e-07 30.5 0.6 0.2 12.0 0.1 4.9 5 0 0 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORX98186.1 - 4e-07 29.8 2.3 2.4 9.0 0.1 6.7 6 0 0 6 6 6 1 Ankyrin repeat Ank_4 PF13637.6 ORX98186.1 - 6.4e-07 29.8 0.6 0.5 11.0 0.0 4.9 4 1 0 5 5 4 2 Ankyrin repeats (many copies) KAP_NTPase PF07693.14 ORX98186.1 - 3.1e-06 26.7 0.1 4e-05 23.0 0.1 2.3 1 1 1 2 2 2 1 KAP family P-loop domain ATPase_2 PF01637.18 ORX98186.1 - 0.057 13.3 0.0 0.37 10.7 0.0 2.2 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Ank PF00023.30 ORX98186.1 - 0.085 13.3 1.5 27 5.4 0.0 5.1 6 1 0 6 6 5 0 Ankyrin repeat AAA_19 PF13245.6 ORX98186.1 - 0.091 13.1 0.0 0.33 11.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 ORX98186.1 - 0.098 13.1 0.1 0.48 10.9 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Cation_efflux PF01545.21 ORX98187.1 - 2.9e-24 85.9 5.4 3.6e-24 85.6 5.4 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 ORX98187.1 - 0.0011 19.0 0.0 0.0025 17.9 0.0 1.5 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter Tudor-knot PF11717.8 ORX98187.1 - 0.034 14.0 0.2 0.076 12.9 0.2 1.6 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain PIRT PF15099.6 ORX98187.1 - 7.8 6.1 6.3 0.64 9.6 1.1 1.8 2 1 0 2 2 2 0 Phosphoinositide-interacting protein family Pkinase PF00069.25 ORX98189.1 - 2.5e-39 135.2 0.0 3.7e-39 134.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX98189.1 - 1.9e-26 92.9 0.0 2.7e-26 92.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_4 PF13637.6 ORX98190.1 - 1.1e-08 35.5 0.1 2.1e-08 34.6 0.1 1.4 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORX98190.1 - 5.2e-07 29.5 0.1 0.049 14.2 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 ORX98190.1 - 1.1e-06 29.2 0.0 1.6e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 ORX98190.1 - 9.6e-06 25.8 0.1 0.0033 17.8 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 ORX98190.1 - 0.00065 19.9 0.0 0.0013 19.0 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) TauD PF02668.16 ORX98191.1 - 3e-33 115.8 0.1 4.6e-33 115.1 0.1 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 ORX98191.1 - 0.01 15.0 0.0 0.016 14.4 0.0 1.2 1 0 0 1 1 1 0 CsiD TilS PF09179.11 ORX98191.1 - 0.053 14.0 2.6 0.52 10.8 1.3 2.6 2 0 0 2 2 2 0 TilS substrate binding domain Amidase PF01425.21 ORX98192.1 - 5.8e-37 127.7 0.0 9.5e-37 127.0 0.0 1.2 1 0 0 1 1 1 1 Amidase NT5C PF06941.12 ORX98192.1 - 0.073 12.9 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) Zn_clus PF00172.18 ORX98193.1 - 0.049 13.8 4.6 0.084 13.0 4.6 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain CorA PF01544.18 ORX98194.1 - 0.0012 18.2 0.4 0.002 17.5 0.4 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Paramecium_SA PF01508.16 ORX98213.1 - 6 7.4 46.7 1.8e+04 -18.9 46.7 3.5 1 1 0 1 1 1 0 Paramecium surface antigen domain Viral_NABP PF05515.11 ORX98241.1 - 0.038 13.8 0.1 0.06 13.2 0.1 1.3 1 0 0 1 1 1 0 Viral nucleic acid binding Glyco_hydro_71 PF03659.14 ORX98242.1 - 1.4e-126 422.4 2.5 1.8e-126 422.0 2.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Abhydrolase_6 PF12697.7 ORX98243.1 - 3e-09 37.8 0.5 1.2e-08 35.9 0.5 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Haem_degrading PF03928.14 ORX98244.1 - 1e-29 103.0 0.4 1.2e-29 102.8 0.4 1.0 1 0 0 1 1 1 1 Haem-degrading EthD PF07110.11 ORX98245.1 - 0.00083 20.5 0.0 0.0011 20.1 0.0 1.2 1 0 0 1 1 1 1 EthD domain Mito_fiss_reg PF05308.11 ORX98246.1 - 0.42 10.7 4.8 0.58 10.2 4.8 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator RPN2_C PF18004.1 ORX98246.1 - 2 8.3 4.9 24 4.8 4.9 2.2 1 1 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Inhibitor_I9 PF05922.16 ORX98247.1 - 0.00092 19.8 0.1 0.0012 19.4 0.1 1.3 1 0 0 1 1 1 1 Peptidase inhibitor I9 RIBIOP_C PF04950.12 ORX98248.1 - 7.9e-96 320.9 0.1 7.9e-96 320.9 0.1 2.0 2 0 0 2 2 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 ORX98248.1 - 3e-28 97.7 0.0 9e-28 96.2 0.0 1.9 1 0 0 1 1 1 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.27 ORX98248.1 - 1.6e-06 27.8 0.0 0.0004 20.0 0.0 2.4 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 ORX98248.1 - 3e-05 24.3 0.0 8e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ORX98248.1 - 0.00053 20.4 0.0 0.0015 18.9 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.23 ORX98248.1 - 0.00085 19.4 0.0 0.0025 17.9 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA PF00004.29 ORX98248.1 - 0.0013 19.2 0.0 0.0034 17.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 ORX98248.1 - 0.0035 17.5 0.0 0.0035 17.5 0.0 2.9 3 0 0 3 3 2 1 AAA domain NB-ARC PF00931.22 ORX98248.1 - 0.0063 15.7 0.0 0.012 14.8 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain ABC_tran PF00005.27 ORX98248.1 - 0.0079 16.7 0.1 0.0079 16.7 0.1 2.1 2 0 0 2 2 1 1 ABC transporter KAP_NTPase PF07693.14 ORX98248.1 - 0.014 14.7 0.0 0.027 13.7 0.0 1.4 1 0 0 1 1 1 0 KAP family P-loop domain AAA_19 PF13245.6 ORX98248.1 - 0.02 15.2 0.1 0.041 14.2 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 ORX98248.1 - 0.025 14.1 0.0 0.076 12.5 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region cobW PF02492.19 ORX98248.1 - 0.026 14.1 0.1 0.05 13.2 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 ORX98248.1 - 0.027 14.4 0.0 0.056 13.4 0.0 1.4 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.22 ORX98248.1 - 0.04 14.3 0.0 0.1 13.0 0.0 1.7 1 0 0 1 1 1 0 RNA helicase PduV-EutP PF10662.9 ORX98248.1 - 0.041 13.6 0.1 0.31 10.8 0.1 2.0 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation MobB PF03205.14 ORX98248.1 - 0.048 13.6 0.5 0.18 11.7 0.1 2.2 3 0 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_30 PF13604.6 ORX98248.1 - 0.048 13.4 0.0 0.093 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 ORX98248.1 - 0.053 14.1 0.2 0.053 14.1 0.2 3.7 4 0 0 4 4 3 0 AAA domain NTPase_1 PF03266.15 ORX98248.1 - 0.063 13.2 0.3 0.12 12.3 0.3 1.4 1 0 0 1 1 1 0 NTPase AAA_14 PF13173.6 ORX98248.1 - 0.098 12.7 0.1 0.38 10.8 0.1 1.9 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 ORX98248.1 - 0.11 12.5 0.1 0.31 11.0 0.1 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RsgA_GTPase PF03193.16 ORX98248.1 - 0.11 12.4 0.0 0.43 10.5 0.0 1.9 2 0 0 2 2 2 0 RsgA GTPase Roc PF08477.13 ORX98248.1 - 0.16 12.2 0.0 0.38 11.0 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 ORX98248.1 - 0.16 11.7 0.0 0.35 10.6 0.0 1.6 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein MeaB PF03308.16 ORX98248.1 - 0.2 10.6 0.0 0.2 10.6 0.0 2.2 2 0 0 2 2 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Mitofilin PF09731.9 ORX98290.1 - 1.3e-136 457.1 20.3 6.1e-117 392.0 17.2 2.0 1 1 1 2 2 2 2 Mitochondrial inner membrane protein Focal_AT PF03623.13 ORX98290.1 - 0.0038 17.2 1.0 0.0038 17.2 1.0 2.3 1 1 1 2 2 2 1 Focal adhesion targeting region Exonuc_VII_L PF02601.15 ORX98290.1 - 0.038 13.6 5.7 0.059 12.9 5.7 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit RPW8 PF05659.11 ORX98290.1 - 0.66 9.7 4.2 1.4 8.6 4.2 1.6 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Baculo_PEP_C PF04513.12 ORX98290.1 - 0.8 9.7 3.6 2.7 8.0 0.2 2.4 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4449 PF14613.6 ORX98290.1 - 1.8 8.6 8.8 7 6.7 8.8 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF4449) ALMT PF11744.8 ORX98290.1 - 8.9 5.0 12.3 17 4.1 12.3 1.4 1 1 0 1 1 1 0 Aluminium activated malate transporter Syja_N PF02383.18 ORX98292.1 - 1.8e-86 290.3 0.0 2.4e-86 290.0 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain Ras PF00071.22 ORX98293.1 - 1e-58 197.5 0.3 1.2e-58 197.3 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORX98293.1 - 5.3e-36 123.5 0.2 9.1e-36 122.7 0.1 1.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORX98293.1 - 1.3e-14 54.0 0.1 1.7e-14 53.7 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 ORX98293.1 - 9.5e-07 28.9 0.0 1.6e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 ORX98293.1 - 1.8e-06 27.5 0.0 2.2e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 ORX98293.1 - 2.3e-06 27.3 0.0 3.3e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 ORX98293.1 - 2e-05 24.5 1.4 0.1 12.5 0.2 2.4 1 1 2 3 3 3 2 RsgA GTPase AAA_16 PF13191.6 ORX98293.1 - 0.005 17.2 0.3 0.01 16.2 0.3 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 ORX98293.1 - 0.021 15.1 0.0 2.4 8.4 0.0 2.3 1 1 1 2 2 2 0 AAA domain TniB PF05621.11 ORX98293.1 - 0.15 11.4 0.0 0.35 10.2 0.0 1.6 1 0 0 1 1 1 0 Bacterial TniB protein CMAS PF02353.20 ORX98296.1 - 8.3e-15 54.8 0.0 1.1e-14 54.4 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.6 ORX98296.1 - 4.2e-13 49.3 0.0 5.4e-13 49.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORX98296.1 - 4.3e-13 49.8 0.0 6e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORX98296.1 - 4.6e-13 49.6 0.0 6.4e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORX98296.1 - 1.9e-10 40.8 0.0 2.5e-10 40.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORX98296.1 - 7.4e-08 33.0 0.0 1.1e-07 32.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 ORX98296.1 - 1.6e-06 28.0 0.0 2e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 ORX98296.1 - 1.8e-06 27.6 0.0 2.4e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 ORX98296.1 - 2.1e-06 27.3 0.0 3e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) UPF0020 PF01170.18 ORX98296.1 - 7.7e-06 25.7 0.1 1.9e-05 24.4 0.0 1.4 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 MetW PF07021.12 ORX98296.1 - 1.6e-05 24.6 0.0 2.2e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_15 PF09445.10 ORX98296.1 - 0.00011 21.8 0.0 0.00014 21.4 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_18 PF12847.7 ORX98296.1 - 0.00015 21.7 0.0 0.0002 21.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain TPMT PF05724.11 ORX98296.1 - 0.00025 20.8 0.0 0.00037 20.2 0.0 1.3 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Ubie_methyltran PF01209.18 ORX98296.1 - 0.0022 17.4 0.0 0.0028 17.0 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_9 PF08003.11 ORX98296.1 - 0.0037 16.2 0.0 0.0046 15.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Met_10 PF02475.16 ORX98296.1 - 0.0043 16.8 0.0 0.0056 16.4 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein GRA6 PF05084.13 ORX98296.1 - 0.005 16.8 0.1 0.0083 16.1 0.1 1.3 1 0 0 1 1 1 1 Granule antigen protein (GRA6) Methyltransf_32 PF13679.6 ORX98296.1 - 0.0053 16.8 0.0 0.0064 16.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_10 PF05971.12 ORX98296.1 - 0.032 13.6 0.0 0.038 13.3 0.0 1.1 1 0 0 1 1 1 0 RNA methyltransferase Methyltransf_4 PF02390.17 ORX98296.1 - 0.081 12.4 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase TehB PF03848.14 ORX98296.1 - 0.12 11.8 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB TrmK PF04816.12 ORX98296.1 - 0.17 11.4 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 tRNA (adenine(22)-N(1))-methyltransferase COesterase PF00135.28 ORX98297.1 - 1.2e-57 196.0 0.0 1.5e-57 195.6 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 ORX98297.1 - 3.6e-06 27.0 0.0 0.015 15.2 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 ORX98297.1 - 0.022 14.3 0.0 0.036 13.6 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF2974 PF11187.8 ORX98297.1 - 0.11 12.1 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Sugar_tr PF00083.24 ORX98298.1 - 1.7e-78 264.5 24.8 2e-78 264.3 24.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORX98298.1 - 3.1e-17 62.5 36.4 3.1e-17 62.5 36.4 2.1 1 1 2 3 3 3 3 Major Facilitator Superfamily Arteri_Gl PF00951.18 ORX98298.1 - 3.9 7.3 6.9 1 9.1 2.7 2.2 1 1 1 2 2 2 0 Arterivirus GL envelope glycoprotein Zn_clus PF00172.18 ORX98299.1 - 1.3e-05 25.2 11.8 1.3e-05 25.2 11.8 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_32N PF00251.20 ORX98300.1 - 5.4e-42 144.4 0.0 1.6e-41 142.9 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 ORX98300.1 - 3.5e-26 92.1 0.0 5.1e-26 91.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal BNR_6 PF15899.5 ORX98300.1 - 0.068 13.3 0.7 13 6.2 0.1 3.5 3 0 0 3 3 3 0 BNR-Asp box repeat BNR PF02012.20 ORX98300.1 - 0.43 10.8 6.1 2.6 8.4 0.8 3.4 2 0 0 2 2 2 0 BNR/Asp-box repeat CBM_20 PF00686.19 ORX98301.1 - 7.3e-30 102.7 0.4 2.1e-29 101.3 0.4 1.8 2 0 0 2 2 2 1 Starch binding domain LPMO_10 PF03067.15 ORX98301.1 - 8.9e-08 33.0 2.8 1.1e-07 32.7 2.0 1.6 2 0 0 2 2 2 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Glyco_hydro_61 PF03443.14 ORX98301.1 - 0.0027 17.7 0.3 0.018 15.0 0.1 2.3 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 Alpha-amylase PF00128.24 ORX98302.1 - 6.2e-58 196.9 0.1 3.6e-57 194.4 0.1 1.9 1 1 0 1 1 1 1 Alpha amylase, catalytic domain CBM_20 PF00686.19 ORX98302.1 - 4e-31 106.8 0.7 8.9e-31 105.7 0.7 1.6 1 0 0 1 1 1 1 Starch binding domain DUF1966 PF09260.11 ORX98302.1 - 0.00012 22.2 0.1 0.00035 20.8 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) hDGE_amylase PF14701.6 ORX98302.1 - 0.012 14.7 0.0 0.019 14.1 0.0 1.2 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain TRAM_LAG1_CLN8 PF03798.16 ORX98304.1 - 6.8e-15 55.3 0.0 8.5e-15 55.0 0.0 1.1 1 0 0 1 1 1 1 TLC domain p450 PF00067.22 ORX98305.1 - 3.4e-13 49.2 0.0 1.5e-12 47.0 0.0 1.8 2 0 0 2 2 2 1 Cytochrome P450 MFS_1 PF07690.16 ORX98306.1 - 1.4e-19 70.3 28.4 1.4e-19 70.3 28.4 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 ORX98306.1 - 7.7e-07 27.8 6.7 1.8e-06 26.6 6.7 1.7 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family PAP2_3 PF14378.6 ORX98307.1 - 0.0047 16.6 0.8 0.0079 15.9 0.3 1.4 1 1 0 1 1 1 1 PAP2 superfamily Peptidase_M56 PF05569.11 ORX98307.1 - 0.081 12.1 0.2 0.11 11.7 0.2 1.3 1 1 0 1 1 1 0 BlaR1 peptidase M56 FA_hydroxylase PF04116.13 ORX98308.1 - 2.6e-10 40.8 9.7 2.6e-10 40.8 9.7 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily CDP-OH_P_transf PF01066.21 ORX98309.1 - 1.6e-10 41.6 3.5 1.8e-10 41.4 0.3 2.4 3 0 0 3 3 3 1 CDP-alcohol phosphatidyltransferase SPT16 PF08644.11 ORX98310.1 - 7.9e-54 181.9 0.3 7.9e-54 181.9 0.3 3.3 5 0 0 5 5 5 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.6 ORX98310.1 - 2.1e-47 160.9 1.7 3e-47 160.4 0.3 2.2 2 0 0 2 2 2 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.24 ORX98310.1 - 2.9e-25 89.2 0.0 4.9e-25 88.5 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 ORX98310.1 - 9.6e-16 58.0 0.1 3.2e-15 56.3 0.0 2.0 2 0 0 2 2 2 1 Histone chaperone Rttp106-like Mito_carr PF00153.27 ORX98311.1 - 1.8e-16 59.8 1.1 5.5e-12 45.5 0.1 3.2 3 1 0 3 3 3 2 Mitochondrial carrier protein SAP PF02037.27 ORX98313.1 - 2.3e-12 46.3 0.1 4.8e-12 45.3 0.1 1.6 1 0 0 1 1 1 1 SAP domain Tho1_MOS11_C PF18592.1 ORX98313.1 - 0.047 13.5 1.8 0.047 13.5 1.8 2.1 2 0 0 2 2 2 0 Tho1/MOS11 C-terminal domain MFS_1 PF07690.16 ORX98314.1 - 6.4e-25 87.8 73.3 1.3e-20 73.6 40.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TMEM40 PF15817.5 ORX98314.1 - 9.6 6.0 7.3 1 9.1 2.2 2.0 2 0 0 2 2 2 0 Transmembrane protein 40 family RRM_1 PF00076.22 ORX98315.1 - 5.1e-09 35.8 0.0 1.7e-08 34.1 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ANAPC4_WD40 PF12894.7 ORX98316.1 - 9.9e-07 29.0 0.0 0.00064 20.0 0.0 2.7 2 1 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 ORX98316.1 - 3.9e-06 27.5 5.8 0.048 14.5 0.7 5.0 4 1 0 4 4 4 3 WD domain, G-beta repeat LisH PF08513.11 ORX98316.1 - 0.079 12.9 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 LisH PQQ PF01011.21 ORX98316.1 - 0.17 11.9 0.0 0.66 10.0 0.0 1.9 2 0 0 2 2 2 0 PQQ enzyme repeat SET PF00856.28 ORX98317.1 - 1e-05 26.0 0.0 0.00014 22.3 0.0 2.4 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.18 ORX98317.1 - 0.00075 19.5 5.8 0.00075 19.5 5.8 2.1 2 0 0 2 2 2 1 MYND finger zf-C2HCIx2C PF10782.9 ORX98317.1 - 0.21 11.6 1.6 0.39 10.7 0.0 2.3 3 0 0 3 3 3 0 Zinc-finger AviRa PF11599.8 ORX98318.1 - 0.037 13.5 0.1 0.048 13.1 0.1 1.2 1 0 0 1 1 1 0 RRNA methyltransferase AviRa NACHT PF05729.12 ORX98360.1 - 3.4e-08 33.6 0.1 3.7e-07 30.2 0.0 2.5 2 1 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 ORX98360.1 - 6.8e-06 26.4 0.0 2e-05 24.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ORX98360.1 - 3.9e-05 24.1 0.0 0.00011 22.7 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain NACHT_N PF17100.5 ORX98360.1 - 4.2e-05 23.5 0.2 8.8e-05 22.5 0.2 1.5 1 0 0 1 1 1 1 N-terminal domain of NWD NACHT-NTPase Ank_2 PF12796.7 ORX98360.1 - 0.0034 17.9 0.1 0.053 14.1 0.0 2.8 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ORX98360.1 - 0.027 15.0 0.1 0.32 11.7 0.0 2.9 2 0 0 2 2 2 0 Ankyrin repeat AAA_19 PF13245.6 ORX98360.1 - 0.044 14.1 0.0 0.16 12.3 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 ORX98360.1 - 0.053 13.9 0.0 0.37 11.2 0.0 2.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Ank PF00023.30 ORX98360.1 - 0.054 14.0 0.2 0.91 10.1 0.1 3.1 2 1 0 2 2 2 0 Ankyrin repeat Get5_C PF18514.1 ORX98360.1 - 0.097 12.4 0.1 1.4 8.7 0.0 2.8 2 0 0 2 2 2 0 Get5 C-terminal domain Viral_helicase1 PF01443.18 ORX98360.1 - 0.17 11.6 0.0 0.44 10.2 0.0 1.7 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Ank_2 PF12796.7 ORX98361.1 - 1.9e-19 70.0 4.0 0.0006 20.3 0.1 5.9 3 2 3 6 6 6 6 Ankyrin repeats (3 copies) DUF1024 PF06260.12 ORX98361.1 - 2.5e-06 27.7 26.0 30 5.0 0.1 11.7 5 4 8 13 13 13 0 Protein of unknown function (DUF1024) Head_binding PF09008.10 ORX98361.1 - 1.3e-05 25.5 24.9 7.2 6.9 0.1 10.4 1 1 9 12 12 12 1 Head binding Rtf2 PF04641.12 ORX98361.1 - 0.00061 19.2 5.0 11 5.3 0.0 5.6 4 3 3 7 7 7 1 Rtf2 RING-finger IRF-2BP1_2 PF11261.8 ORX98361.1 - 0.0023 17.4 2.3 13 5.4 0.0 5.2 6 0 0 6 6 6 0 Interferon regulatory factor 2-binding protein zinc finger DUF3888 PF13027.6 ORX98361.1 - 0.0038 17.6 9.0 29 5.2 0.1 7.2 5 3 3 9 9 9 0 Protein of unknown function (DUF3888) YqgF PF14639.6 ORX98361.1 - 0.015 15.1 12.6 12 5.6 0.2 6.5 2 2 5 8 8 8 0 Holliday-junction resolvase-like of SPT6 PepSY_like PF11396.8 ORX98361.1 - 0.017 15.7 1.9 1.4e+02 3.1 0.0 5.2 4 2 2 6 6 6 0 Putative beta-lactamase-inhibitor-like, PepSY-like Fil_haemagg PF05594.14 ORX98361.1 - 0.018 15.6 39.0 32 5.2 1.2 10.5 3 3 6 9 9 9 0 Haemagluttinin repeat SseB_C PF14581.6 ORX98361.1 - 0.34 11.0 9.8 42 4.3 0.2 5.8 1 1 9 10 10 10 0 SseB protein C-terminal domain AAA PF00004.29 ORX98361.1 - 0.7 10.3 11.8 12 6.3 0.4 5.6 2 1 1 5 5 5 0 ATPase family associated with various cellular activities (AAA) Fer2_4 PF13510.6 ORX98361.1 - 0.76 9.9 11.5 75 3.5 0.1 6.7 5 2 4 9 9 9 0 2Fe-2S iron-sulfur cluster binding domain Succ_CoA_lig PF13607.6 ORX98361.1 - 1.9 8.3 6.8 0.87 9.4 0.6 3.1 2 1 1 3 3 3 0 Succinyl-CoA ligase like flavodoxin domain FTR_C PF02741.15 ORX98361.1 - 7.4 6.6 13.0 19 5.2 0.1 4.6 3 1 0 4 4 4 0 FTR, proximal lobe Ank_2 PF12796.7 ORX98362.1 - 8.6e-09 35.9 0.0 1e-08 35.6 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ORX98362.1 - 1.4e-08 34.3 0.1 0.0019 18.5 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 ORX98362.1 - 4.2e-08 33.3 0.2 0.012 16.1 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 ORX98362.1 - 4.3e-07 30.1 1.2 0.00035 20.8 0.1 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 ORX98362.1 - 8.7e-06 26.2 0.1 5.6e-05 23.6 0.1 1.9 1 1 0 1 1 1 1 Ankyrin repeats (many copies) NmrA PF05368.13 ORX98363.1 - 1.1e-07 31.7 0.0 1.4e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ORX98363.1 - 6.2e-07 29.5 0.0 7e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 ORX98363.1 - 1.5e-06 27.5 0.0 1.7e-06 27.3 0.0 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 ORX98363.1 - 0.00025 20.6 0.0 0.00029 20.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 ORX98363.1 - 0.00028 21.3 0.1 0.00046 20.6 0.1 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 ORX98363.1 - 0.0003 21.1 0.1 0.00044 20.5 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_4 PF07993.12 ORX98363.1 - 0.00053 19.2 0.6 0.007 15.6 0.0 2.1 2 1 0 2 2 2 1 Male sterility protein Shikimate_DH PF01488.20 ORX98363.1 - 0.0017 18.4 0.0 0.0024 17.9 0.0 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase PNP_UDP_1 PF01048.20 ORX98363.1 - 0.0092 15.3 0.0 0.01 15.1 0.0 1.2 1 0 0 1 1 1 1 Phosphorylase superfamily GGACT PF06094.12 ORX98363.1 - 0.029 15.0 0.1 0.088 13.4 0.1 1.7 1 1 1 2 2 2 0 Gamma-glutamyl cyclotransferase, AIG2-like DapB_N PF01113.20 ORX98363.1 - 0.037 14.1 0.0 0.054 13.6 0.0 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus ADH_N PF08240.12 ORX98364.1 - 5.7e-18 64.8 0.0 1e-17 64.0 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORX98364.1 - 4.3e-12 46.1 0.1 7e-12 45.5 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 ORX98364.1 - 0.00049 19.7 0.1 0.00093 18.7 0.1 1.4 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 ORX98364.1 - 0.00053 21.1 0.0 0.0009 20.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_7 PF13241.6 ORX98364.1 - 0.0055 17.1 0.0 0.0095 16.4 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding DAO PF01266.24 ORX98364.1 - 0.019 14.5 0.3 0.17 11.4 0.6 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 ORX98364.1 - 0.036 13.3 0.5 0.058 12.6 0.5 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.14 ORX98364.1 - 0.055 12.7 0.3 0.077 12.2 0.3 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase zf-ribbon_3 PF13248.6 ORX98364.1 - 6.8 6.3 6.0 3.3 7.3 3.1 1.9 2 0 0 2 2 2 0 zinc-ribbon domain Glyco_hydro_cc PF11790.8 ORX98365.1 - 1.1e-47 162.6 0.0 1.4e-47 162.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core DUF4392 PF14336.6 ORX98365.1 - 0.04 13.4 0.0 0.057 12.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4392) Amidohydro_3 PF07969.11 ORX98366.1 - 2.3e-12 47.1 1.3 1.6e-07 31.2 0.1 2.9 3 0 0 3 3 3 2 Amidohydrolase family Amidohydro_1 PF01979.20 ORX98366.1 - 6.2e-08 32.3 0.0 1.9e-06 27.5 0.0 2.4 2 0 0 2 2 2 1 Amidohydrolase family FixH PF05751.11 ORX98368.1 - 0.15 12.1 0.1 0.19 11.8 0.1 1.2 1 0 0 1 1 1 0 FixH Alpha-amylase PF00128.24 ORX98373.1 - 1.3e-19 71.0 0.5 3.8e-19 69.4 0.5 1.9 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.11 ORX98373.1 - 3.4e-16 59.7 0.1 6.7e-16 58.7 0.1 1.4 1 0 0 1 1 1 1 Starch synthase catalytic domain Glyco_trans_1_4 PF13692.6 ORX98373.1 - 5.3e-06 26.9 0.0 1.2e-05 25.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 ORX98373.1 - 6.2e-05 22.6 0.0 0.00012 21.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 ORX98373.1 - 0.054 13.5 0.0 0.16 12.0 0.0 1.7 1 0 0 1 1 1 0 Glycosyltransferase Family 4 Beta-lactamase PF00144.24 ORX98374.1 - 7.2e-10 38.6 0.0 8.1e-10 38.4 0.0 1.0 1 0 0 1 1 1 1 Beta-lactamase p450 PF00067.22 ORX98375.1 - 2.6e-31 108.9 0.0 6.2e-31 107.7 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 DUF2997 PF11211.8 ORX98375.1 - 0.12 12.2 0.4 0.49 10.2 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2997) BNR_2 PF13088.6 ORX98376.1 - 0.0084 15.4 0.1 0.019 14.3 0.1 1.5 1 1 0 1 1 1 1 BNR repeat-like domain Pkinase PF00069.25 ORX98418.1 - 2e-65 220.8 0.0 2.4e-65 220.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX98418.1 - 1e-34 120.0 0.0 1.2e-34 119.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 ORX98418.1 - 0.0013 17.8 0.0 0.0029 16.6 0.0 1.6 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 ORX98418.1 - 0.022 14.1 0.2 0.063 12.6 0.2 1.7 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 ORX98418.1 - 0.026 14.4 0.1 0.037 13.9 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 ORX98418.1 - 0.054 12.8 0.1 0.19 11.0 0.0 1.7 1 1 0 2 2 2 0 Kinase-like WD40 PF00400.32 ORX98419.1 - 6e-19 68.0 10.1 1.4e-05 25.7 0.2 6.8 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX98419.1 - 0.013 15.8 0.0 0.072 13.4 0.0 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain DPM2 PF07297.12 ORX98420.1 - 2.2e-32 111.2 2.2 2.5e-32 111.0 2.2 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.12 ORX98420.1 - 0.00011 22.0 1.7 0.00013 21.9 1.7 1.1 1 0 0 1 1 1 1 PIG-P COX14 PF14880.6 ORX98420.1 - 0.0046 16.8 2.8 0.024 14.5 0.1 2.1 2 0 0 2 2 2 1 Cytochrome oxidase c assembly DUF2198 PF09964.9 ORX98420.1 - 0.0062 16.6 2.1 0.52 10.4 0.3 2.2 2 0 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2198) DUF4229 PF14012.6 ORX98420.1 - 0.0077 16.3 0.2 0.0077 16.3 0.2 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF4229) LapA_dom PF06305.11 ORX98420.1 - 0.014 15.2 0.2 0.014 15.2 0.2 1.9 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain MA3 PF02847.17 ORX98421.1 - 4e-25 88.0 0.4 1.1e-24 86.5 0.1 2.0 2 0 0 2 2 2 1 MA3 domain MIF4G PF02854.19 ORX98421.1 - 6.7e-10 39.0 0.8 1.5e-09 37.9 0.8 1.6 1 0 0 1 1 1 1 MIF4G domain Cnd1 PF12717.7 ORX98421.1 - 0.12 12.4 0.5 0.26 11.3 0.5 1.5 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 Saf_2TM PF18303.1 ORX98423.1 - 0.15 11.6 1.8 8.9 5.9 0.1 2.4 2 0 0 2 2 2 0 SAVED-fused 2TM effector domain DUF4064 PF13273.6 ORX98423.1 - 4.7 7.5 8.5 30 5.0 3.9 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) HET PF06985.11 ORX98424.1 - 1.2e-36 126.3 0.7 2.7e-36 125.1 0.2 1.9 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Stealth_CR4 PF17103.5 ORX98424.1 - 0.086 12.7 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Stealth protein CR4, conserved region 4 Fer2_3 PF13085.6 ORX98425.1 - 0.0022 18.0 3.7 0.0036 17.3 3.7 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain zf-B_box PF00643.24 ORX98425.1 - 0.11 12.7 9.5 1.7 8.9 5.2 2.6 2 1 0 2 2 2 0 B-box zinc finger FYVE_2 PF02318.16 ORX98425.1 - 0.42 10.8 4.5 0.87 9.8 4.5 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger Memo PF01875.17 ORX98426.1 - 6.6e-68 228.8 0.0 8.9e-68 228.4 0.0 1.1 1 0 0 1 1 1 1 Memo-like protein APH PF01636.23 ORX98427.1 - 2.2e-10 40.9 0.1 5.5e-09 36.3 0.1 2.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 ORX98427.1 - 0.00073 18.8 0.0 0.0012 18.1 0.0 1.3 1 0 0 1 1 1 1 Fructosamine kinase DUF4853 PF16145.5 ORX98427.1 - 0.14 12.3 0.1 0.79 9.9 0.0 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4853) AMP-binding PF00501.28 ORX98428.1 - 3e-67 227.1 0.0 4.3e-67 226.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORX98428.1 - 2.2e-13 51.0 0.2 5.9e-13 49.6 0.1 1.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain BolA PF01722.18 ORX98429.1 - 4.8e-31 106.9 1.6 6e-31 106.5 1.6 1.1 1 0 0 1 1 1 1 BolA-like protein Cofilin_ADF PF00241.20 ORX98429.1 - 0.074 12.9 0.1 0.091 12.6 0.1 1.2 1 0 0 1 1 1 0 Cofilin/tropomyosin-type actin-binding protein NADH_dehy_S2_C PF06444.11 ORX98430.1 - 2.9 8.5 5.7 11 6.6 0.1 2.7 3 0 0 3 3 3 0 NADH dehydrogenase subunit 2 C-terminus Gpr1_Fun34_YaaH PF01184.19 ORX98431.1 - 1.7e-87 292.4 15.5 2e-87 292.1 15.5 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Adeno_E3B PF03376.14 ORX98431.1 - 0.064 13.5 0.3 0.16 12.3 0.3 1.6 1 0 0 1 1 1 0 Adenovirus E3B protein AAA PF00004.29 ORX98434.1 - 2.1e-17 63.8 0.0 3.9e-17 62.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 ORX98434.1 - 0.018 15.3 0.0 0.048 13.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 ORX98434.1 - 0.16 12.4 0.1 0.49 10.8 0.1 2.0 1 1 0 1 1 1 0 RNA helicase WD40 PF00400.32 ORX98436.1 - 2.8e-27 94.4 6.1 8e-07 29.7 0.0 7.1 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX98436.1 - 9.9e-13 48.2 0.0 0.017 15.4 0.0 4.6 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ORX98436.1 - 0.0011 18.9 0.0 4.7 7.0 0.0 3.3 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.6 ORX98436.1 - 0.022 14.4 0.0 0.089 12.4 0.0 2.0 1 1 0 1 1 1 0 PQQ-like domain Cornichon PF03311.14 ORX98437.1 - 1.3e-50 170.8 12.7 1.5e-50 170.6 12.7 1.0 1 0 0 1 1 1 1 Cornichon protein Peptidase_M24 PF00557.24 ORX98438.1 - 2.6e-45 154.7 0.0 3.1e-45 154.4 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 ORX98438.1 - 1.8e-18 66.6 9.9 4.3e-18 65.4 9.9 1.7 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 ORX98438.1 - 0.00063 19.8 7.1 0.00063 19.8 7.1 2.4 2 0 0 2 2 2 1 MYND finger zf-HIT PF04438.16 ORX98438.1 - 2.8 7.9 8.0 0.66 9.9 4.0 2.1 2 0 0 2 2 2 0 HIT zinc finger FAD_binding_3 PF01494.19 ORX98439.1 - 2.5e-19 69.7 0.0 5.7e-19 68.6 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 ORX98439.1 - 6.9e-06 25.5 0.0 1.5e-05 24.4 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORX98439.1 - 1.1e-05 25.8 0.0 0.0031 18.0 0.0 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 ORX98439.1 - 0.00044 19.4 0.0 0.00077 18.6 0.0 1.3 1 0 0 1 1 1 1 Squalene epoxidase GIDA PF01134.22 ORX98439.1 - 0.0014 17.8 0.0 0.0021 17.2 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 ORX98439.1 - 0.0054 16.1 0.0 0.0084 15.4 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 ORX98439.1 - 0.0062 16.2 0.2 0.015 14.9 0.2 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 ORX98439.1 - 0.029 13.1 0.1 0.043 12.5 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein FAD_oxidored PF12831.7 ORX98439.1 - 0.062 12.6 0.4 0.16 11.3 0.4 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ORX98439.1 - 0.11 12.8 0.1 0.28 11.4 0.1 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain zf-RING_2 PF13639.6 ORX98440.1 - 3.3e-05 24.1 2.3 6.6e-05 23.2 2.3 1.5 1 1 0 1 1 1 1 Ring finger domain zf-ANAPC11 PF12861.7 ORX98440.1 - 0.00015 21.7 0.6 0.00025 21.0 0.6 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 ORX98440.1 - 0.00079 19.7 1.6 0.0013 18.9 1.6 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 ORX98440.1 - 0.0019 18.1 1.7 0.0035 17.3 1.7 1.5 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 ORX98440.1 - 0.024 14.5 2.5 0.041 13.8 2.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 ORX98440.1 - 0.1 12.4 1.0 0.23 11.3 1.0 1.6 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 BIR PF00653.21 ORX98440.1 - 0.11 13.1 0.0 9.5 7.0 0.0 2.6 2 0 0 2 2 2 0 Inhibitor of Apoptosis domain zf-RING_UBOX PF13445.6 ORX98440.1 - 0.14 12.2 4.9 0.088 12.8 2.9 1.7 1 1 1 2 2 2 0 RING-type zinc-finger zf-RING_11 PF17123.5 ORX98440.1 - 0.19 11.5 2.8 7.9 6.3 0.4 2.3 2 0 0 2 2 2 0 RING-like zinc finger zf-C3HC4_2 PF13923.6 ORX98440.1 - 2.5 8.0 6.0 0.61 10.0 2.0 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DMPK_coil PF08826.10 ORX98441.1 - 0.004 17.2 0.2 0.0063 16.6 0.2 1.2 1 0 0 1 1 1 1 DMPK coiled coil domain like Lipase_GDSL_2 PF13472.6 ORX98444.1 - 6e-22 78.9 0.5 1.2e-21 77.9 0.5 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 ORX98444.1 - 5e-12 46.2 0.1 7.6e-12 45.6 0.1 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Pkinase PF00069.25 ORX98445.1 - 1.8e-36 125.9 0.0 2e-36 125.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX98445.1 - 3e-24 85.7 0.0 3.7e-24 85.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 ORX98445.1 - 0.0018 17.7 0.1 0.0024 17.3 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 ORX98445.1 - 0.074 12.0 0.1 0.093 11.7 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH PF01636.23 ORX98445.1 - 0.087 12.7 0.0 0.17 11.8 0.0 1.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family Abhydrolase_6 PF12697.7 ORX98447.1 - 6.5e-20 72.7 0.1 7.5e-20 72.5 0.1 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORX98447.1 - 0.00017 20.9 0.0 0.0012 18.1 0.0 2.2 1 1 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 ORX98447.1 - 0.0014 18.4 0.1 0.0023 17.7 0.1 1.4 1 0 0 1 1 1 1 PGAP1-like protein Lipase_2 PF01674.18 ORX98447.1 - 0.01 15.4 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 2) LRR_8 PF13855.6 ORX98520.1 - 3.5e-06 26.7 0.1 7.1e-06 25.7 0.1 1.5 1 1 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 ORX98520.1 - 3.2e-05 24.2 0.2 0.0017 18.7 0.0 2.2 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 ORX98520.1 - 0.068 13.3 0.4 26 5.2 0.0 3.2 3 0 0 3 3 3 0 Leucine Rich repeat LRR_1 PF00560.33 ORX98520.1 - 0.21 12.3 0.2 2e+02 3.2 0.0 3.4 3 0 0 3 3 3 0 Leucine Rich Repeat RGS PF00615.19 ORX98523.1 - 2.8e-11 43.7 0.0 4.5e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain DUF647 PF04884.14 ORX98524.1 - 4.3e-109 363.8 2.3 7.5e-109 363.0 2.3 1.4 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis DAO PF01266.24 ORX98526.1 - 6.8e-50 170.6 0.0 1.2e-49 169.8 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 ORX98526.1 - 6.4e-42 142.4 0.2 1.1e-41 141.6 0.2 1.4 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_binding_2 PF00890.24 ORX98526.1 - 4.5e-07 29.3 0.5 1.8e-06 27.3 0.5 1.8 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 ORX98526.1 - 0.0014 18.1 0.8 0.0073 15.7 0.5 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ORX98526.1 - 0.0021 17.4 0.6 0.0064 15.7 0.6 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORX98526.1 - 0.011 16.0 1.3 0.038 14.2 0.3 2.5 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 ORX98526.1 - 0.039 13.2 0.1 0.1 11.8 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 ORX98526.1 - 0.083 12.8 0.6 0.16 11.9 0.1 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.14 ORX98526.1 - 0.1 11.3 0.2 0.17 10.5 0.2 1.3 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.27 ORX98526.1 - 0.14 12.8 0.3 0.41 11.2 0.3 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase VTC PF09359.10 ORX98527.1 - 1.1e-09 38.2 0.0 2.2e-08 33.9 0.0 2.3 1 1 0 1 1 1 1 VTC domain SPX PF03105.19 ORX98527.1 - 1.2e-06 28.8 21.8 0.0013 18.7 0.0 4.6 3 2 1 4 4 4 3 SPX domain DUF3915 PF13054.6 ORX98527.1 - 0.086 12.8 0.1 0.17 11.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) ALS_ss_C PF10369.9 ORX98528.1 - 1.1e-14 54.4 0.0 9.9e-14 51.3 0.0 2.2 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.25 ORX98528.1 - 7.4e-13 48.0 0.1 1.5e-12 47.1 0.1 1.6 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.6 ORX98528.1 - 2e-08 34.0 0.0 4.7e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 ACT domain HHH_6 PF14579.6 ORX98528.1 - 0.13 12.6 0.0 0.31 11.3 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif Aconitase PF00330.20 ORX98529.1 - 1.6e-141 472.5 0.0 2.4e-141 471.9 0.0 1.3 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 ORX98529.1 - 5.7e-38 130.2 0.0 1e-37 129.4 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain KH_1 PF00013.29 ORX98529.1 - 1.2e-07 31.4 0.0 1.1e-05 25.2 0.0 2.6 2 0 0 2 2 2 1 KH domain DUF1857 PF08982.11 ORX98530.1 - 8.4e-49 165.2 0.0 9.4e-49 165.0 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1857) Sigma70_r4_2 PF08281.12 ORX98530.1 - 0.057 13.1 0.1 0.1 12.3 0.1 1.3 1 0 0 1 1 1 0 Sigma-70, region 4 DSPc PF00782.20 ORX98531.1 - 2.1e-27 95.5 0.0 3.1e-27 95.0 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Yippee-Mis18 PF03226.14 ORX98531.1 - 0.047 13.9 2.4 0.2 11.9 1.4 2.3 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zinc_ribbon_4 PF13717.6 ORX98531.1 - 0.34 10.8 2.8 23 5.0 0.1 2.9 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2 PF00096.26 ORX98533.1 - 0.00012 22.3 19.2 0.012 16.0 1.2 4.7 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORX98533.1 - 0.057 14.3 22.9 0.57 11.2 1.6 4.9 4 0 0 4 4 4 0 C2H2-type zinc finger zf-CHCC PF10276.9 ORX98533.1 - 0.41 10.8 2.4 15 5.7 0.1 2.4 2 0 0 2 2 2 0 Zinc-finger domain Ogr_Delta PF04606.12 ORX98535.1 - 0.037 14.0 2.5 0.087 12.8 0.5 2.3 2 1 0 2 2 2 0 Ogr/Delta-like zinc finger Vfa1 PF08432.10 ORX98536.1 - 2.1e-55 187.8 14.7 2.4e-55 187.7 14.7 1.0 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 MTBP_N PF14918.6 ORX98536.1 - 0.0044 16.5 4.3 0.0097 15.4 4.3 1.6 1 1 0 1 1 1 1 MDM2-binding CDC45 PF02724.14 ORX98536.1 - 0.1 10.9 9.7 0.099 10.9 9.7 1.0 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.12 ORX98536.1 - 0.12 12.2 7.7 0.14 12.0 7.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF3449 PF11931.8 ORX98536.1 - 0.2 11.5 8.0 0.29 10.9 8.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) DUF913 PF06025.12 ORX98536.1 - 0.5 9.3 2.3 0.62 9.0 2.3 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) GCD14 PF08704.10 ORX98536.1 - 0.79 9.4 5.5 1.2 8.8 5.5 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Paramyxo_ncap PF00973.19 ORX98536.1 - 2 7.2 5.8 2.3 7.0 5.8 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein FAM60A PF15396.6 ORX98536.1 - 2.1 8.3 12.5 3.3 7.7 9.8 2.0 2 0 0 2 2 2 0 Protein Family FAM60A DUF4407 PF14362.6 ORX98536.1 - 2.7 7.3 7.9 3.1 7.1 7.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Afi1 PF07792.12 ORX98536.1 - 4.4 7.8 14.0 6.5 7.2 13.7 1.4 1 1 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking PPL5 PF18168.1 ORX98536.1 - 5 6.3 9.7 6.2 6.0 9.7 1.1 1 0 0 1 1 1 0 Prim-pol family 5 Connexin PF00029.19 ORX98536.1 - 5.2 6.8 7.2 6.7 6.4 7.2 1.2 1 0 0 1 1 1 0 Connexin Presenilin PF01080.17 ORX98536.1 - 5.7 5.6 7.4 6.6 5.4 7.4 1.1 1 0 0 1 1 1 0 Presenilin EMC3_TMCO1 PF01956.16 ORX98536.1 - 8.9 6.0 9.7 8.9 6.0 9.1 1.4 1 1 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like TatD_DNase PF01026.21 ORX98537.1 - 1.4e-52 178.6 0.0 1.7e-52 178.3 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase Hydrolase PF00702.26 ORX98537.1 - 0.05 13.9 0.0 0.18 12.0 0.0 1.8 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Glyco_hydro_16 PF00722.21 ORX98538.1 - 0.0031 17.0 0.0 0.0059 16.1 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 UbiA PF01040.18 ORX98539.1 - 6e-43 147.0 20.2 7.7e-43 146.6 20.2 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family JmjC PF02373.22 ORX98540.1 - 2.3e-10 40.9 0.4 1.6e-09 38.2 0.4 2.3 1 1 0 1 1 1 1 JmjC domain, hydroxylase zf-4CXXC_R1 PF10497.9 ORX98540.1 - 1.5e-08 34.8 7.0 1.5e-08 34.8 7.0 2.6 2 0 0 2 2 2 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Cupin_2 PF07883.11 ORX98540.1 - 0.0029 17.3 0.0 0.008 15.9 0.0 1.7 1 0 0 1 1 1 1 Cupin domain HHH PF00633.23 ORX98541.1 - 0.0029 17.4 0.1 0.0092 15.8 0.1 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.6 ORX98541.1 - 0.047 14.3 0.2 0.13 12.9 0.0 1.9 2 0 0 2 2 2 0 Helix-hairpin-helix domain HalX PF08663.10 ORX98541.1 - 0.081 13.3 0.6 0.21 12.0 0.6 1.6 1 0 0 1 1 1 0 HalX domain CENP-N PF05238.13 ORX98542.1 - 3.1e-122 408.9 0.0 3.5e-122 408.7 0.0 1.0 1 0 0 1 1 1 1 Kinetochore protein CHL4 like DUF3511 PF12023.8 ORX98542.1 - 0.12 12.3 0.5 0.22 11.4 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3511) bZIP_2 PF07716.15 ORX98543.1 - 1.2e-12 47.7 15.0 2.2e-12 46.9 15.0 1.4 1 0 0 1 1 1 1 Basic region leucine zipper XhlA PF10779.9 ORX98543.1 - 0.012 15.8 3.5 0.022 15.0 3.5 1.4 1 0 0 1 1 1 0 Haemolysin XhlA bZIP_1 PF00170.21 ORX98543.1 - 0.028 14.5 10.9 0.069 13.2 10.9 1.6 1 1 0 1 1 1 0 bZIP transcription factor TSC22 PF01166.18 ORX98543.1 - 0.034 14.4 0.3 0.06 13.7 0.3 1.4 1 0 0 1 1 1 0 TSC-22/dip/bun family Shugoshin_N PF07558.11 ORX98543.1 - 0.044 13.7 1.3 0.074 12.9 1.3 1.4 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region Matrilin_ccoil PF10393.9 ORX98543.1 - 0.053 13.4 1.0 0.22 11.4 1.4 1.8 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin bZIP_Maf PF03131.17 ORX98543.1 - 0.098 13.2 6.1 0.16 12.5 6.1 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor GIT_CC PF16559.5 ORX98543.1 - 0.25 11.2 1.9 0.45 10.4 1.9 1.3 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor PspB PF06667.12 ORX98543.1 - 0.49 10.5 1.6 0.87 9.7 1.6 1.4 1 0 0 1 1 1 0 Phage shock protein B DUF1192 PF06698.11 ORX98543.1 - 0.51 10.4 7.6 0.77 9.9 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) Tctex-1 PF03645.13 ORX98544.1 - 5.5e-35 119.7 0.1 6.1e-35 119.6 0.1 1.0 1 0 0 1 1 1 1 Tctex-1 family DUF202 PF02656.15 ORX98545.1 - 2.3e-14 53.6 8.5 3.4e-14 53.0 2.8 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF202) Jnk-SapK_ap_N PF09744.9 ORX98600.1 - 0.013 15.7 1.6 0.013 15.7 1.6 3.5 2 1 2 4 4 4 0 JNK_SAPK-associated protein-1 RasGAP_C PF03836.15 ORX98600.1 - 0.021 14.9 2.0 0.021 14.9 2.0 3.3 3 2 2 5 5 5 0 RasGAP C-terminus CHDCT2 PF08074.11 ORX98600.1 - 0.49 10.6 9.6 0.11 12.6 1.1 2.8 2 0 0 2 2 2 0 CHDCT2 (NUC038) domain Cnn_1N PF07989.11 ORX98600.1 - 3.2 8.0 18.8 0.82 9.9 1.3 4.3 1 1 3 4 4 4 0 Centrosomin N-terminal motif 1 bZIP_1 PF00170.21 ORX98600.1 - 3.6 7.8 14.7 0.19 11.8 0.9 4.6 3 1 0 4 4 4 0 bZIP transcription factor TRAUB PF08164.12 ORX98600.1 - 5.6 7.5 7.4 15 6.2 3.5 3.0 2 0 0 2 2 2 0 Apoptosis-antagonizing transcription factor, C-terminal DUF5320 PF17253.2 ORX98600.1 - 8.5 7.5 6.9 35 5.6 0.2 3.5 3 1 0 3 3 3 0 Family of unknown function (DUF5320) RNA_polI_A34 PF08208.11 ORX98601.1 - 7.7e-44 150.3 2.4 7.7e-44 150.3 2.4 2.9 2 1 1 3 3 3 1 DNA-directed RNA polymerase I subunit RPA34.5 DUF4667 PF15700.5 ORX98601.1 - 4.6 7.3 14.6 0.086 12.9 7.6 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4667) CLP1_P PF16575.5 ORX98602.1 - 2.1e-13 50.5 0.0 1.2e-12 48.0 0.0 2.1 1 1 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_33 PF13671.6 ORX98602.1 - 0.13 12.5 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Lactamase_B_3 PF13483.6 ORX98603.1 - 4.2e-08 33.2 0.0 8.2e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 ORX98603.1 - 0.011 15.3 0.0 0.016 14.7 0.0 1.2 1 0 0 1 1 1 0 Beta-lactamase superfamily domain C1_2 PF03107.16 ORX98604.1 - 4.1 7.8 10.7 1.7 9.0 7.7 2.0 2 0 0 2 2 2 0 C1 domain GRASP55_65 PF04495.14 ORX98606.1 - 2.6e-48 163.8 0.0 2.7e-45 154.1 0.0 2.1 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_6 PF17820.1 ORX98606.1 - 0.00026 20.7 0.1 0.16 11.8 0.0 2.4 2 0 0 2 2 2 2 PDZ domain Methyltransf_15 PF09445.10 ORX98607.1 - 2.4e-48 163.8 0.0 3e-48 163.5 0.0 1.1 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Met_10 PF02475.16 ORX98607.1 - 6e-08 32.7 0.0 8.9e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein UPF0020 PF01170.18 ORX98607.1 - 0.00045 20.0 0.0 0.002 17.9 0.0 1.8 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Cons_hypoth95 PF03602.15 ORX98607.1 - 0.00084 19.0 0.0 0.0012 18.5 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_5 PF01795.19 ORX98607.1 - 0.0025 17.4 0.0 0.0034 16.9 0.0 1.2 1 0 0 1 1 1 1 MraW methylase family MTS PF05175.14 ORX98607.1 - 0.017 14.7 0.0 0.022 14.3 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_18 PF12847.7 ORX98607.1 - 0.026 14.5 0.0 0.041 13.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 ORX98607.1 - 0.033 14.9 0.0 0.056 14.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DNA_methylase PF00145.17 ORX98607.1 - 0.035 13.4 0.1 0.049 13.0 0.1 1.2 1 0 0 1 1 1 0 C-5 cytosine-specific DNA methylase TRM PF02005.16 ORX98607.1 - 0.037 13.2 0.0 0.052 12.7 0.0 1.2 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_31 PF13847.6 ORX98607.1 - 0.058 13.2 0.0 0.071 12.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 ORX98607.1 - 0.12 11.7 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DUF3591 PF12157.8 ORX98608.1 - 2.4e-174 580.1 0.1 2.4e-174 580.1 0.1 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3591) zf-CCHC PF00098.23 ORX98608.1 - 0.0043 17.1 0.7 0.0087 16.1 0.7 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 ORX98608.1 - 0.011 15.5 1.2 0.032 14.1 1.2 1.7 1 0 0 1 1 1 0 Zinc knuckle zf-C2H2_4 PF13894.6 ORX98610.1 - 3.2e-05 24.4 10.9 0.12 13.2 0.1 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.26 ORX98610.1 - 0.0012 19.2 14.4 0.019 15.4 0.1 3.7 3 1 0 3 3 3 3 Zinc finger, C2H2 type FOXP-CC PF16159.5 ORX98610.1 - 0.0013 19.3 4.1 0.0089 16.6 0.0 2.4 2 0 0 2 2 2 1 FOXP coiled-coil domain FixP_N PF14715.6 ORX98612.1 - 0.14 12.0 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of cytochrome oxidase-cbb3, FixP Dopey_N PF04118.14 ORX98613.1 - 1.5e-114 382.3 0.0 4.6e-114 380.7 0.0 1.9 1 0 0 1 1 1 1 Dopey, N-terminal MazG PF03819.17 ORX98613.1 - 0.089 13.0 0.0 1.7 8.9 0.0 2.9 2 0 0 2 2 2 0 MazG nucleotide pyrophosphohydrolase domain HEAT_EZ PF13513.6 ORX98613.1 - 1.5 9.4 5.5 90 3.7 0.0 5.1 5 0 0 5 5 5 0 HEAT-like repeat Aldose_epim PF01263.20 ORX98614.1 - 6.2e-62 209.6 0.1 7.8e-62 209.3 0.1 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Zn_clus PF00172.18 ORX98615.1 - 6e-09 35.9 13.4 1.2e-08 34.9 13.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Y_phosphatase PF00102.27 ORX98617.1 - 5e-56 189.9 0.0 6.3e-56 189.6 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 ORX98617.1 - 0.0022 17.8 0.0 0.0059 16.4 0.0 1.8 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Mrx7 PF10906.8 ORX98618.1 - 8.7e-07 29.1 0.0 9.4e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 MIOREX complex component 7 TonB_2 PF13103.6 ORX98618.1 - 0.066 13.5 0.0 0.1 12.9 0.0 1.3 1 0 0 1 1 1 0 TonB C terminal Mon1 PF03164.14 ORX98619.1 - 2.4e-144 481.4 0.0 2.8e-144 481.1 0.0 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 HeLo PF14479.6 ORX98620.1 - 1.1e-43 149.5 0.0 1.7e-43 148.9 0.0 1.3 1 0 0 1 1 1 1 Prion-inhibition and propagation Ras PF00071.22 ORX98620.1 - 1e-15 57.7 0.0 1.6e-15 57.1 0.0 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORX98620.1 - 2.2e-05 24.7 0.0 4.1e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AMP-binding PF00501.28 ORX98661.1 - 1.4e-26 93.1 0.0 2.3e-26 92.4 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 ORX98661.1 - 7.3e-26 90.8 0.4 2.7e-23 82.4 0.0 2.6 3 0 0 3 3 3 2 Condensation domain PP-binding PF00550.25 ORX98661.1 - 0.0001 22.6 0.1 0.00024 21.4 0.1 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site TPR_12 PF13424.6 ORX98663.1 - 3.9e-16 59.1 13.9 2.4e-07 31.0 0.1 5.2 3 2 1 4 4 4 2 Tetratricopeptide repeat NB-ARC PF00931.22 ORX98663.1 - 1.9e-11 43.6 0.0 1.4e-10 40.8 0.0 2.1 1 1 0 1 1 1 1 NB-ARC domain TPR_1 PF00515.28 ORX98663.1 - 2.1e-09 36.8 6.0 0.00064 19.4 0.2 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 ORX98663.1 - 2.2e-08 33.7 15.2 0.00087 19.1 0.1 5.9 6 0 0 6 6 6 3 Tetratricopeptide repeat PGAP1 PF07819.13 ORX98663.1 - 2.7e-06 27.3 0.0 5.7e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein TPR_2 PF07719.17 ORX98663.1 - 5.4e-06 26.1 21.8 7.1e-05 22.6 0.6 5.7 7 0 0 7 7 6 3 Tetratricopeptide repeat AAA_16 PF13191.6 ORX98663.1 - 6.2e-06 26.7 0.8 5.3e-05 23.7 0.0 3.1 4 1 0 4 4 3 1 AAA ATPase domain Abhydrolase_6 PF12697.7 ORX98663.1 - 1.3e-05 25.9 2.8 1.5e-05 25.7 0.2 2.3 3 0 0 3 3 3 1 Alpha/beta hydrolase family TPR_7 PF13176.6 ORX98663.1 - 0.00021 21.1 4.8 1.9 8.7 0.0 5.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_MalT PF17874.1 ORX98663.1 - 0.00035 20.0 1.7 0.00035 20.0 1.7 2.0 2 0 0 2 2 2 1 MalT-like TPR region DUF676 PF05057.14 ORX98663.1 - 0.0012 18.4 0.0 0.0021 17.6 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) AAA_22 PF13401.6 ORX98663.1 - 0.0061 16.8 0.0 0.073 13.3 0.0 2.8 3 0 0 3 3 3 1 AAA domain TPR_4 PF07721.14 ORX98663.1 - 0.0083 16.7 0.3 0.6 10.9 0.0 4.4 5 0 0 5 5 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 ORX98663.1 - 0.016 15.8 0.3 4.7 7.9 0.1 2.9 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 ORX98663.1 - 0.024 14.8 8.9 0.079 13.2 0.4 4.6 5 0 0 5 5 4 0 Tetratricopeptide repeat LCAT PF02450.15 ORX98663.1 - 0.03 13.5 0.0 0.13 11.3 0.0 2.0 2 0 0 2 2 2 0 Lecithin:cholesterol acyltransferase TPR_11 PF13414.6 ORX98663.1 - 0.035 13.8 3.7 5.2 6.9 0.2 4.4 3 1 0 3 3 3 0 TPR repeat IstB_IS21 PF01695.17 ORX98663.1 - 0.038 13.7 0.0 0.11 12.2 0.0 1.8 1 0 0 1 1 1 0 IstB-like ATP binding protein TPR_19 PF14559.6 ORX98663.1 - 0.04 14.4 0.1 0.04 14.4 0.1 4.1 6 0 0 6 6 3 0 Tetratricopeptide repeat NACHT PF05729.12 ORX98663.1 - 0.074 13.0 0.0 0.36 10.7 0.0 2.3 2 1 0 2 2 1 0 NACHT domain TniB PF05621.11 ORX98663.1 - 0.1 12.0 0.0 0.29 10.5 0.0 1.7 1 0 0 1 1 1 0 Bacterial TniB protein Parvo_NS1 PF01057.17 ORX98663.1 - 0.13 11.3 0.0 0.28 10.2 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 TPR_14 PF13428.6 ORX98663.1 - 2.6 9.1 17.1 24 6.1 0.0 7.2 8 1 1 9 9 6 0 Tetratricopeptide repeat MFS_1 PF07690.16 ORX98664.1 - 2.5e-45 154.9 37.3 2.5e-45 154.9 37.3 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORX98664.1 - 1.9e-12 46.8 10.9 1.9e-12 46.8 10.9 2.0 2 1 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 ORX98664.1 - 2e-08 33.1 4.9 3.6e-08 32.3 4.9 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) FA_desaturase PF00487.24 ORX98664.1 - 0.77 9.5 13.5 0.23 11.3 1.2 2.9 2 1 1 3 3 3 0 Fatty acid desaturase Pox_G9-A16 PF03003.16 ORX98665.1 - 0.074 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Pox virus entry-fusion-complex G9/A16 CorA PF01544.18 ORX98667.1 - 7.4e-09 35.3 0.2 1.8e-08 34.1 0.2 1.6 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Glyco_hydro_11 PF00457.17 ORX98668.1 - 1e-60 204.4 13.4 1.3e-60 204.1 13.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 CENP-O PF09496.10 ORX98669.1 - 1.5e-52 178.7 0.1 3.1e-52 177.6 0.1 1.5 1 1 0 1 1 1 1 Cenp-O kinetochore centromere component Acatn PF13000.7 ORX98670.1 - 9.1e-165 549.3 14.2 2.5e-83 280.4 5.8 3.1 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 AhpC-TSA PF00578.21 ORX98671.1 - 2.7e-31 108.1 0.0 3.6e-31 107.7 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.9 ORX98671.1 - 5.9e-14 51.6 0.2 1.1e-13 50.8 0.2 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.10 ORX98671.1 - 1.5e-12 47.4 0.0 1.9e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 Redoxin PLA2_B PF01735.18 ORX98672.1 - 7.3e-176 585.4 3.7 8.9e-176 585.1 3.7 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain Ion_trans_2 PF07885.16 ORX98673.1 - 7.6e-28 96.3 19.7 1.6e-16 60.0 5.0 3.2 3 0 0 3 3 3 2 Ion channel Htr2 PF17909.1 ORX98673.1 - 0.017 15.4 1.2 0.11 12.8 0.5 2.5 2 0 0 2 2 2 0 Htr2 transmembrane domain zf-CHY PF05495.12 ORX98673.1 - 0.044 14.3 0.2 0.12 12.9 0.2 1.6 1 0 0 1 1 1 0 CHY zinc finger IBV_3C PF03620.13 ORX98673.1 - 0.13 12.8 2.3 1.8 9.1 0.2 2.8 2 0 0 2 2 2 0 IBV 3C protein CrgA PF06781.12 ORX98673.1 - 0.23 11.6 1.1 1.5 9.0 0.1 2.6 2 0 0 2 2 2 0 Cell division protein CrgA Neur_chan_memb PF02932.16 ORX98673.1 - 0.27 11.3 1.1 1.7 8.7 1.1 2.3 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Lig_chan PF00060.26 ORX98673.1 - 0.7 9.7 6.8 0.66 9.8 0.2 3.2 2 1 0 2 2 2 0 Ligand-gated ion channel ETRAMP PF09716.10 ORX98673.1 - 2.4 8.3 3.8 58 3.9 0.1 3.2 3 0 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) G6B PF15096.6 ORX98675.1 - 0.1 12.4 0.4 0.1 12.4 0.4 2.0 1 1 1 2 2 2 0 G6B family Endostatin PF06482.11 ORX98675.1 - 0.72 9.3 4.0 0.79 9.1 4.0 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin SID-1_RNA_chan PF13965.6 ORX98675.1 - 0.89 7.9 5.9 0.86 7.9 5.9 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Plasmodium_Vir PF05795.11 ORX98675.1 - 6.3 6.1 19.1 6.8 6.0 19.1 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein AAA_11 PF13086.6 ORX98675.1 - 9.4 5.9 15.7 10 5.8 15.7 1.2 1 0 0 1 1 1 0 AAA domain p450 PF00067.22 ORX98676.1 - 1.8e-48 165.5 0.0 2.2e-48 165.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Sugar_tr PF00083.24 ORX98677.1 - 1.4e-79 268.1 26.3 1.7e-79 267.8 26.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORX98677.1 - 3.7e-23 82.0 34.9 1.9e-20 73.1 26.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_3_C PF01915.22 ORX98678.1 - 1.1e-46 159.4 0.0 1.5e-46 159.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 ORX98678.1 - 1.1e-43 149.8 0.0 1.7e-43 149.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 ORX98678.1 - 6.9e-12 45.3 0.5 1.6e-11 44.2 0.5 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 ORX98678.1 - 2.3e-06 27.5 0.0 7.2e-06 25.9 0.0 1.8 1 1 1 2 2 2 1 PA14 domain MFS_1 PF07690.16 ORX98679.1 - 7.1e-23 81.1 55.0 9.4e-13 47.8 17.8 2.4 1 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 ORX98679.1 - 2e-07 29.9 28.2 2.7e-07 29.4 28.2 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Lipase_3 PF01764.25 ORX98680.1 - 1.7e-05 24.7 0.0 3.2e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 ORX98680.1 - 0.0093 15.2 0.0 0.015 14.5 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 ORX98680.1 - 0.028 14.2 0.0 0.053 13.3 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family UPF0227 PF05728.12 ORX98680.1 - 0.17 11.8 0.0 0.27 11.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Fructosamin_kin PF03881.14 ORX98681.1 - 3.4e-73 246.4 0.0 3.9e-73 246.2 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 ORX98681.1 - 0.0088 16.0 0.0 0.015 15.3 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 ORX98681.1 - 0.0091 14.9 0.0 0.013 14.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) DUF1772 PF08592.11 ORX98682.1 - 3e-17 63.2 2.8 3.7e-17 62.9 2.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) Lipase_GDSL_2 PF13472.6 ORX98683.1 - 1.1e-16 61.8 0.1 1.2e-15 58.4 0.1 2.1 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 ORX98683.1 - 1.5e-08 34.8 0.1 3.9e-08 33.5 0.1 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Baculo_ME53 PF06061.11 ORX98683.1 - 0.048 12.9 0.0 0.069 12.4 0.0 1.2 1 0 0 1 1 1 0 Baculoviridae ME53 GFA PF04828.14 ORX98685.1 - 2.6e-23 82.1 0.4 3.9e-23 81.6 0.4 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zf-NADH-PPase PF09297.11 ORX98685.1 - 0.046 13.4 0.4 0.046 13.4 0.4 2.3 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain zinc_ribbon_2 PF13240.6 ORX98685.1 - 0.05 13.3 4.6 0.14 12.0 0.3 2.5 2 0 0 2 2 2 0 zinc-ribbon domain Sgf11 PF08209.11 ORX98685.1 - 0.13 11.8 0.9 0.13 11.8 0.9 2.0 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) Porin_10 PF14121.6 ORX98685.1 - 0.18 10.3 0.0 0.21 10.1 0.0 1.1 1 0 0 1 1 1 0 Putative porin OTT_1508_deam PF14441.6 ORX98686.1 - 9.6e-19 67.2 0.1 2.5e-18 65.9 0.1 1.7 1 0 0 1 1 1 1 OTT_1508-like deaminase zf-MYND PF01753.18 ORX98686.1 - 0.0074 16.4 10.0 0.015 15.4 10.0 1.6 1 0 0 1 1 1 1 MYND finger DUF1965 PF09248.10 ORX98686.1 - 0.011 15.5 0.3 0.031 14.0 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1965) Cullin PF00888.22 ORX98722.1 - 3.8e-190 633.6 11.9 5.3e-190 633.1 11.9 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 ORX98722.1 - 1e-26 92.7 4.7 4.4e-26 90.7 4.7 2.2 1 0 0 1 1 1 1 Cullin protein neddylation domain WAC_Acf1_DNA_bd PF10537.9 ORX98722.1 - 0.027 15.0 1.8 0.13 12.8 0.7 2.8 2 0 0 2 2 2 0 ATP-utilising chromatin assembly and remodelling N-terminal MT-A70 PF05063.14 ORX98722.1 - 1.2 9.1 4.4 1.9 8.4 1.2 2.3 2 0 0 2 2 2 0 MT-A70 DUF1803 PF08820.10 ORX98722.1 - 5.1 7.2 8.0 12 6.0 0.2 3.9 3 2 0 3 3 3 0 Domain of unknown function (DUF1803) MARVEL PF01284.23 ORX98723.1 - 0.00021 21.4 6.3 0.0003 20.8 6.3 1.2 1 0 0 1 1 1 1 Membrane-associating domain Mit_KHE1 PF10173.9 ORX98724.1 - 6.6e-60 202.5 2.1 6.6e-60 202.5 2.1 1.7 2 0 0 2 2 2 1 Mitochondrial K+-H+ exchange-related Lipin_N PF04571.14 ORX98724.1 - 0.12 12.4 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 lipin, N-terminal conserved region adh_short_C2 PF13561.6 ORX98725.1 - 1.1e-64 218.2 0.0 1.4e-64 217.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORX98725.1 - 3.5e-51 173.4 0.0 5.2e-51 172.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORX98725.1 - 3.6e-07 30.3 0.1 9.5e-07 28.9 0.1 1.7 1 1 0 1 1 1 1 KR domain PALP PF00291.25 ORX98725.1 - 0.0086 15.5 0.1 0.014 14.8 0.1 1.4 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme 2-Hacid_dh_C PF02826.19 ORX98725.1 - 0.073 12.4 0.0 0.16 11.3 0.0 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TatD_DNase PF01026.21 ORX98726.1 - 2.4e-23 82.8 0.0 8.5e-23 81.0 0.0 1.8 1 1 0 1 1 1 1 TatD related DNase RXT2_N PF08595.11 ORX98726.1 - 0.048 13.7 0.2 0.083 12.9 0.2 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF1664 PF07889.12 ORX98726.1 - 0.073 13.1 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Tyrosinase PF00264.20 ORX98727.1 - 2.7e-52 178.3 2.2 3.4e-52 177.9 2.2 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase GAD-like PF08887.11 ORX98728.1 - 0.024 14.4 0.1 0.079 12.7 0.0 1.8 1 1 1 2 2 2 0 GAD-like domain APH PF01636.23 ORX98729.1 - 1.4e-12 48.1 0.0 4.5e-12 46.4 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 ORX98729.1 - 0.00016 21.0 0.1 0.0013 18.1 0.1 2.2 2 1 1 3 3 3 1 Fructosamine kinase Pkinase PF00069.25 ORX98729.1 - 0.0023 17.3 0.2 0.6 9.4 0.1 2.1 2 0 0 2 2 2 2 Protein kinase domain Choline_kinase PF01633.20 ORX98729.1 - 0.027 14.0 0.1 0.17 11.5 0.1 2.0 1 1 0 1 1 1 0 Choline/ethanolamine kinase HrpJ PF07201.11 ORX98729.1 - 0.2 11.9 0.0 0.34 11.2 0.0 1.3 1 0 0 1 1 1 0 HrpJ-like domain Glyco_hydro_45 PF02015.16 ORX98730.1 - 1.7e-66 224.2 15.7 1.7e-66 224.2 15.7 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 45 CBM_1 PF00734.18 ORX98730.1 - 2.5e-24 84.9 54.5 4.4e-12 45.7 7.7 5.0 5 0 0 5 5 5 3 Fungal cellulose binding domain ATG_C PF09333.11 ORX98731.1 - 1.5e-05 25.3 0.0 9.7e-05 22.6 0.0 2.5 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain VPS13_C PF16909.5 ORX98731.1 - 0.11 12.3 1.5 0.2 11.4 0.3 2.1 3 0 0 3 3 3 0 Vacuolar-sorting-associated 13 protein C-terminal E1-E2_ATPase PF00122.20 ORX98733.1 - 2.8e-20 72.6 0.0 6.5e-20 71.4 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 ORX98733.1 - 2.8e-15 57.2 4.3 1.4e-09 38.6 1.8 3.0 3 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 ORX98733.1 - 9.8e-05 22.4 0.1 0.1 12.7 0.1 2.7 2 0 0 2 2 2 2 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 ORX98733.1 - 0.015 15.0 0.0 0.038 13.7 0.0 1.7 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 ORX98733.1 - 0.019 14.7 0.1 0.17 11.6 0.1 2.4 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase DUF4059 PF13268.6 ORX98733.1 - 0.071 13.5 0.2 3.8 8.0 0.0 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4059) G0-G1_switch_2 PF15103.6 ORX98733.1 - 5.4 7.5 5.2 10 6.6 0.0 2.8 3 0 0 3 3 3 0 G0/G1 switch protein 2 DUF4291 PF14124.6 ORX98745.1 - 2.3e-62 210.1 0.1 2.8e-62 209.8 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4291) HMG_CoA_synt_C PF08540.10 ORX98748.1 - 1.1e-104 350.0 0.2 1.4e-104 349.6 0.2 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 ORX98748.1 - 5.4e-96 319.5 0.1 7.9e-96 318.9 0.1 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal COX16 PF14138.6 ORX98749.1 - 3.7e-34 117.1 0.1 5.5e-34 116.5 0.1 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 DUF2304 PF10066.9 ORX98749.1 - 0.16 12.2 0.0 0.25 11.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2304) PI3_PI4_kinase PF00454.27 ORX98750.1 - 2.8e-53 181.3 0.0 6.4e-53 180.1 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 ORX98750.1 - 1.2e-36 126.6 0.0 3.1e-36 125.3 0.0 1.7 1 0 0 1 1 1 1 FAT domain UME PF08064.13 ORX98750.1 - 2.1e-33 114.3 0.0 7.9e-33 112.4 0.0 2.2 1 0 0 1 1 1 1 UME (NUC010) domain FATC PF02260.20 ORX98750.1 - 1.7e-15 56.6 3.1 6.5e-15 54.7 0.0 3.2 3 0 0 3 3 3 1 FATC domain TPR_19 PF14559.6 ORX98750.1 - 0.0072 16.8 0.4 0.27 11.8 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF3385 PF11865.8 ORX98750.1 - 0.025 14.5 0.0 0.1 12.5 0.0 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3385) IFRD PF05004.13 ORX98750.1 - 0.061 12.4 1.5 7 5.7 0.0 3.0 3 0 0 3 3 3 0 Interferon-related developmental regulator (IFRD) dCMP_cyt_deam_1 PF00383.23 ORX98751.1 - 1.7e-21 76.0 0.0 3.6e-21 75.0 0.0 1.5 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 ORX98751.1 - 4.8e-15 55.5 0.0 9e-15 54.6 0.0 1.4 1 1 0 1 1 1 1 MafB19-like deaminase APOBEC3 PF18771.1 ORX98751.1 - 0.00098 19.2 0.0 0.0015 18.6 0.0 1.2 1 0 0 1 1 1 1 APOBEC3 SNAD4 PF18750.1 ORX98751.1 - 0.0038 17.3 0.0 0.0064 16.6 0.0 1.3 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 Bd3614-deam PF14439.6 ORX98751.1 - 0.04 14.0 1.0 0.11 12.6 1.0 1.7 1 1 0 1 1 1 0 Bd3614-like deaminase NAD1 PF18778.1 ORX98751.1 - 0.12 12.4 0.0 0.18 11.8 0.0 1.2 1 0 0 1 1 1 0 Novel AID APOBEC clade 1 APOBEC_N PF08210.11 ORX98751.1 - 0.2 11.5 0.0 0.28 11.0 0.0 1.2 1 0 0 1 1 1 0 APOBEC-like N-terminal domain Cg6151-P PF10233.9 ORX98752.1 - 2e-43 147.3 18.3 2.4e-43 147.0 18.3 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P TraP PF07296.11 ORX98752.1 - 0.098 11.8 0.6 0.15 11.3 0.6 1.2 1 0 0 1 1 1 0 TraP protein T_cell_tran_alt PF15128.6 ORX98752.1 - 0.12 12.2 0.0 0.12 12.2 0.0 1.8 2 0 0 2 2 2 0 T-cell leukemia translocation-altered Cytochrom_B558a PF05038.13 ORX98752.1 - 0.71 9.4 7.4 0.15 11.6 0.2 2.5 2 1 1 3 3 3 0 Cytochrome Cytochrome b558 alpha-subunit CbiN PF02553.15 ORX98752.1 - 0.76 9.8 5.5 0.31 11.1 0.5 2.4 2 0 0 2 2 2 0 Cobalt transport protein component CbiN UPF0258 PF06789.12 ORX98752.1 - 1.2 9.2 3.2 5.1 7.2 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0258) Dpy19 PF10034.9 ORX98752.1 - 1.4 7.0 12.0 1.7 6.8 12.0 1.0 1 0 0 1 1 1 0 Q-cell neuroblast polarisation DUF2721 PF11026.8 ORX98752.1 - 1.6 8.6 18.5 1.3 8.9 6.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) MPS-4 PF17523.2 ORX98752.1 - 6.8 6.9 9.6 0.55 10.4 3.6 2.1 2 1 0 2 2 2 0 MinK-related peptide, potassium channel accessory sub-unit protein 4 Phage_holin_3_6 PF07332.11 ORX98752.1 - 7.9 6.6 17.0 3.3 7.8 6.2 2.1 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Aim21 PF11489.8 ORX98753.1 - 1.3e-219 731.8 66.4 1.3e-219 731.8 66.4 2.2 2 0 0 2 2 2 1 Altered inheritance of mitochondria protein 21 Ank_2 PF12796.7 ORX98755.1 - 4.3e-26 91.3 3.5 2.3e-10 40.9 0.1 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 ORX98755.1 - 3.1e-17 62.1 6.2 0.0047 17.3 0.2 5.1 5 0 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.6 ORX98755.1 - 4.3e-16 59.1 0.5 2.6e-05 24.7 0.0 3.6 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORX98755.1 - 1.4e-13 49.7 0.5 0.021 15.3 0.1 4.9 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 ORX98755.1 - 1.8e-08 34.5 0.9 0.0025 18.1 0.1 4.3 2 2 3 5 5 5 5 Ankyrin repeats (many copies) CorA PF01544.18 ORX98756.1 - 8.3e-13 48.3 0.1 1.6e-12 47.4 0.1 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein TB2_DP1_HVA22 PF03134.19 ORX98757.1 - 2.3e-21 75.5 5.9 4.2e-21 74.7 5.9 1.4 1 0 0 1 1 1 1 TB2/DP1, HVA22 family ABC_tran_Xtn PF12848.7 ORX98757.1 - 0.096 12.7 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Mgm101p PF06420.12 ORX98758.1 - 4.5e-86 286.6 0.0 6.2e-86 286.2 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 p450 PF00067.22 ORX98759.1 - 3.8e-68 230.3 0.0 4.8e-68 230.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CHCH PF06747.13 ORX98760.1 - 1.9e-06 27.8 6.8 2.8e-06 27.3 6.8 1.3 1 0 0 1 1 1 1 CHCH domain CX9C PF16860.5 ORX98760.1 - 0.0023 17.9 1.2 0.072 13.1 0.2 2.2 2 0 0 2 2 2 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Cmc1 PF08583.10 ORX98760.1 - 0.029 14.4 3.8 0.082 12.9 3.8 1.7 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like COX17 PF05051.13 ORX98760.1 - 0.064 13.6 2.3 0.092 13.1 2.3 1.2 1 0 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) BPL_N PF09825.9 ORX98761.1 - 2.3e-146 487.7 0.0 2.8e-146 487.4 0.0 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.19 ORX98761.1 - 1.6e-24 86.3 0.0 3.6e-24 85.2 0.0 1.6 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Glyco_hydro_42M PF08532.10 ORX98761.1 - 0.17 11.3 0.3 0.52 9.8 0.1 1.9 2 0 0 2 2 2 0 Beta-galactosidase trimerisation domain GMC_oxred_N PF00732.19 ORX98764.1 - 3.2e-51 174.4 0.0 5.3e-51 173.8 0.0 1.3 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 ORX98764.1 - 5e-36 124.4 0.0 7.6e-36 123.8 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 ORX98764.1 - 6.8e-05 22.1 0.0 9.7e-05 21.6 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 ORX98764.1 - 0.00017 20.8 0.4 0.36 9.9 0.0 2.5 3 0 0 3 3 3 2 FAD binding domain NAD_binding_8 PF13450.6 ORX98764.1 - 0.00023 21.3 0.1 0.0007 19.8 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ORX98764.1 - 0.0015 18.2 0.1 0.016 14.8 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 ORX98764.1 - 0.032 13.1 0.0 0.047 12.6 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox_2 PF07992.14 ORX98764.1 - 0.043 13.1 0.0 0.18 11.0 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORX98764.1 - 0.098 13.2 0.1 2.9 8.5 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Aldedh PF00171.22 ORX98765.1 - 2.6e-156 520.8 0.2 3e-156 520.6 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Aldo_ket_red PF00248.21 ORX98766.1 - 1.2e-58 198.6 0.0 1.6e-58 198.2 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family adh_short PF00106.25 ORX98767.1 - 4.4e-34 117.6 0.1 6.8e-34 117.0 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORX98767.1 - 6.9e-26 91.2 0.1 1.5e-25 90.2 0.1 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORX98767.1 - 9.7e-13 48.4 0.1 1.5e-12 47.8 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ORX98767.1 - 4.9e-05 22.9 0.3 0.00018 21.0 0.3 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 ORX98767.1 - 0.013 14.7 0.0 0.016 14.4 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein PA PF02225.22 ORX98767.1 - 0.036 14.1 0.2 0.078 13.0 0.2 1.5 1 0 0 1 1 1 0 PA domain RraA-like PF03737.15 ORX98767.1 - 0.083 13.1 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 Aldolase/RraA Shikimate_DH PF01488.20 ORX98767.1 - 0.15 12.1 0.1 0.25 11.4 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase MFS_1 PF07690.16 ORX98769.1 - 8.2e-40 136.8 70.0 3.9e-32 111.5 46.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORX98769.1 - 3.4e-07 29.5 31.1 1.9e-05 23.7 5.2 3.2 3 0 0 3 3 3 3 Sugar (and other) transporter Hva1_TUDOR PF11160.8 ORX98770.1 - 1.7e-14 53.7 1.1 1.9e-14 53.6 1.1 1.0 1 0 0 1 1 1 1 Hypervirulence associated proteins TUDOR domain HlyIII PF03006.20 ORX98771.1 - 1.4e-62 211.3 13.7 1.9e-62 210.9 13.7 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF962 PF06127.11 ORX98771.1 - 0.0069 16.5 0.5 0.023 14.8 0.0 2.4 1 1 1 2 2 2 1 Protein of unknown function (DUF962) TssN PF17555.2 ORX98771.1 - 2.3 7.5 7.8 1.7 8.0 3.5 2.1 1 1 0 2 2 2 0 Type VI secretion system, TssN Colicin_V PF02674.16 ORX98771.1 - 6.5 6.7 9.9 0.29 11.1 3.3 2.1 2 1 0 2 2 2 0 Colicin V production protein Brix PF04427.18 ORX98773.1 - 1.7e-49 168.6 0.0 2.3e-49 168.2 0.0 1.1 1 0 0 1 1 1 1 Brix domain DEAD PF00270.29 ORX98774.1 - 3e-45 154.1 0.0 4.5e-45 153.5 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORX98774.1 - 6.8e-31 106.9 0.0 3.2e-30 104.7 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORX98774.1 - 0.0017 18.4 0.0 0.0033 17.5 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF305 PF03713.13 ORX98774.1 - 0.24 11.6 0.2 0.24 11.6 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF305) Pox_Ag35 PF03286.14 ORX98774.1 - 0.55 10.0 8.6 1.2 8.9 8.6 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein MerB PF03243.15 ORX98775.1 - 0.069 13.3 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Alkylmercury lyase Pkinase PF00069.25 ORX98810.1 - 2.1e-37 128.9 0.0 3e-37 128.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX98810.1 - 2.1e-18 66.6 0.0 2.7e-18 66.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 ORX98810.1 - 0.03 13.7 0.0 0.055 12.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 ORX98810.1 - 0.034 14.1 0.1 0.76 9.6 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Sugar_tr PF00083.24 ORX98812.1 - 1.1e-25 90.4 15.3 2.3e-16 59.7 3.1 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 ORX98812.1 - 1.8e-17 63.3 27.5 1.3e-16 60.5 27.0 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily DnaJ PF00226.31 ORX98815.1 - 1.6e-19 69.8 0.5 1.6e-19 69.8 0.5 2.2 2 0 0 2 2 2 1 DnaJ domain RhgB_N PF09284.10 ORX98816.1 - 9.8e-100 333.2 0.2 1.5e-99 332.6 0.2 1.3 1 0 0 1 1 1 1 Rhamnogalacturonan lyase B, N-terminal CBM-like PF14683.6 ORX98816.1 - 1e-34 119.8 0.0 2.1e-34 118.8 0.0 1.6 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.6 ORX98816.1 - 4.8e-20 71.1 0.6 4.8e-20 71.1 0.6 2.3 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.6 ORX98816.1 - 0.0014 18.9 1.5 0.0088 16.3 0.2 2.7 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain Acylphosphatase PF00708.18 ORX98816.1 - 0.11 12.9 0.0 0.29 11.6 0.0 1.7 1 0 0 1 1 1 0 Acylphosphatase baeRF_family3 PF18845.1 ORX98817.1 - 0.18 12.1 5.3 1.3 9.2 0.6 2.3 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 3 Gly-zipper_YMGG PF13441.6 ORX98817.1 - 1.6 8.5 30.0 35 4.3 2.5 2.3 1 1 1 2 2 2 0 YMGG-like Gly-zipper Gly-zipper_Omp PF13488.6 ORX98817.1 - 2 8.5 29.7 3.5e+02 1.3 29.7 2.4 1 1 0 1 1 1 0 Glycine zipper ZapB PF06005.12 ORX98818.1 - 0.053 14.0 0.3 0.085 13.3 0.3 1.2 1 0 0 1 1 1 0 Cell division protein ZapB REF PF05755.12 ORX98818.1 - 0.055 13.3 0.1 0.087 12.6 0.1 1.2 1 0 0 1 1 1 0 Rubber elongation factor protein (REF) CD225 PF04505.12 ORX98818.1 - 0.077 13.1 0.1 14 5.9 0.0 2.2 2 0 0 2 2 2 0 Interferon-induced transmembrane protein ApoC-I PF04691.12 ORX98818.1 - 0.12 12.3 0.5 0.2 11.6 0.5 1.3 1 0 0 1 1 1 0 Apolipoprotein C-I (ApoC-1) HET PF06985.11 ORX98819.1 - 4.3e-18 66.1 0.1 4.5e-18 66.0 0.1 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DAHP_synth_1 PF00793.20 ORX98819.1 - 0.013 14.3 0.1 0.041 12.7 0.0 1.7 1 1 1 2 2 2 0 DAHP synthetase I family FAD_binding_4 PF01565.23 ORX98821.1 - 2.1e-20 72.9 0.6 4e-20 72.0 0.6 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 ORX98821.1 - 1.6e-10 40.9 0.0 3.5e-10 39.8 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like adh_short PF00106.25 ORX98823.1 - 2.2e-17 63.2 0.0 3.1e-17 62.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORX98823.1 - 3.1e-06 26.9 0.1 4.4e-06 26.4 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORX98823.1 - 0.0025 17.7 0.0 0.0039 17.1 0.0 1.2 1 0 0 1 1 1 1 KR domain Csm1_B PF18211.1 ORX98823.1 - 0.0075 16.1 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 Csm1 subunit domain B GHMP_kinases_C PF08544.13 ORX98823.1 - 0.015 15.6 0.0 0.033 14.6 0.0 1.5 1 0 0 1 1 1 0 GHMP kinases C terminal Stig1 PF04885.13 ORX98824.1 - 0.0052 17.3 2.6 0.011 16.2 2.6 1.4 1 0 0 1 1 1 1 Stigma-specific protein, Stig1 Fungal_trans PF04082.18 ORX98825.1 - 1.4e-13 50.5 0.2 2.5e-13 49.7 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORX98826.1 - 6.6e-10 39.0 7.8 9.3e-10 38.5 7.8 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2841 PF11001.8 ORX98826.1 - 0.072 13.1 0.1 0.12 12.4 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2841) MFS_1 PF07690.16 ORX98827.1 - 1.9e-34 119.1 40.5 1.9e-34 119.1 40.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORX98827.1 - 1.7e-10 40.4 6.2 1.7e-10 40.4 6.2 3.0 2 1 1 3 3 3 2 Sugar (and other) transporter zf-3CxxC PF13695.6 ORX98829.1 - 6.5e-22 77.9 3.8 1.2e-21 77.1 3.8 1.4 1 0 0 1 1 1 1 Zinc-binding domain zf-3CxxC_2 PF17180.4 ORX98829.1 - 0.003 18.2 4.5 1 10.1 1.7 2.9 2 1 0 2 2 2 2 Zinc-binding domain Sugar_tr PF00083.24 ORX98864.1 - 2.1e-15 56.5 6.6 2.6e-12 46.4 6.5 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter Ferric_reduct PF01794.19 ORX98868.1 - 9e-14 51.7 11.9 9e-14 51.7 11.9 1.9 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 ORX98868.1 - 2e-10 40.7 0.0 4.7e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 ORX98868.1 - 0.00012 22.2 0.0 0.00021 21.5 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain DUF4405 PF14358.6 ORX98868.1 - 9.2 6.9 12.5 17 6.0 2.4 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4405) Glyco_hydro_2_C PF02836.17 ORX98871.1 - 1.2e-42 146.1 0.6 6.7e-21 74.7 0.1 3.2 1 1 2 3 3 3 3 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.18 ORX98871.1 - 2.1e-05 24.5 0.1 0.06 13.2 0.0 2.6 2 0 0 2 2 2 2 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.21 ORX98871.1 - 0.017 15.8 0.0 0.05 14.3 0.0 1.8 1 1 0 1 1 1 0 Glycosyl hydrolases family 2 peroxidase PF00141.23 ORX98872.1 - 6e-79 265.0 0.0 1.4e-40 139.5 0.0 2.3 2 0 0 2 2 2 2 Peroxidase NAD_binding_8 PF13450.6 ORX98874.1 - 2.1e-11 43.9 0.4 5.6e-11 42.5 0.1 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 ORX98874.1 - 4.8e-11 42.6 0.1 1.1e-05 24.9 0.1 2.3 2 1 0 2 2 2 2 Flavin containing amine oxidoreductase Thi4 PF01946.17 ORX98874.1 - 0.00065 19.0 0.0 0.0011 18.3 0.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 ORX98874.1 - 0.00068 19.1 0.4 0.0012 18.2 0.2 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 ORX98874.1 - 0.0023 16.7 0.0 0.004 15.9 0.0 1.4 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.24 ORX98874.1 - 0.0073 15.9 0.3 0.014 15.0 0.3 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 ORX98874.1 - 0.0085 16.1 0.3 0.024 14.6 0.1 1.8 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 ORX98874.1 - 0.024 13.7 0.1 0.041 13.0 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.14 ORX98874.1 - 0.032 13.5 0.1 0.054 12.7 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORX98874.1 - 0.04 14.5 0.2 0.15 12.6 0.0 2.0 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.19 ORX98874.1 - 0.17 11.2 0.0 0.3 10.4 0.0 1.3 1 0 0 1 1 1 0 GMC oxidoreductase adh_short PF00106.25 ORX98876.1 - 1.4e-43 148.6 0.4 1.8e-43 148.3 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORX98876.1 - 1.4e-34 119.7 0.0 1.8e-34 119.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORX98876.1 - 5.4e-11 42.7 1.0 7.5e-11 42.3 1.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 ORX98876.1 - 3e-08 33.8 0.1 8.7e-08 32.3 0.1 1.7 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 ORX98876.1 - 6.2e-08 32.5 0.1 1.9e-07 30.9 0.1 1.7 2 0 0 2 2 2 1 NmrA-like family Epimerase PF01370.21 ORX98876.1 - 0.00023 20.7 0.0 0.00035 20.1 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 ORX98876.1 - 0.0013 18.2 0.0 0.16 11.3 0.0 2.2 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) Rossmann-like PF10727.9 ORX98876.1 - 0.0014 18.5 1.3 0.0041 17.0 0.2 2.2 2 1 1 3 3 3 1 Rossmann-like domain Ub-RnfH PF03658.14 ORX98876.1 - 0.0091 16.4 0.0 5.9 7.4 0.0 2.2 2 0 0 2 2 2 2 RnfH family Ubiquitin GDP_Man_Dehyd PF16363.5 ORX98876.1 - 0.0097 15.3 0.0 0.018 14.4 0.0 1.5 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase DFP PF04127.15 ORX98876.1 - 0.01 15.7 0.5 0.018 14.9 0.5 1.3 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein ADH_zinc_N PF00107.26 ORX98876.1 - 0.026 14.5 0.0 0.049 13.6 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase DDE_3 PF13358.6 ORX98883.1 - 0.00011 22.0 0.1 0.00011 21.9 0.1 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease UDPG_MGDP_dh PF00984.19 ORX98928.1 - 2.5e-11 43.6 0.0 3.4e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain CTD_bind PF04818.13 ORX98929.1 - 0.061 14.2 0.0 0.16 12.8 0.0 1.7 2 0 0 2 2 2 0 RNA polymerase II-binding domain. Aminotran_1_2 PF00155.21 ORX98930.1 - 3.6e-10 39.5 0.0 4.1e-10 39.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II EthD PF07110.11 ORX98931.1 - 2.5e-12 47.8 1.4 2.9e-12 47.6 1.4 1.1 1 0 0 1 1 1 1 EthD domain Protocadherin PF08374.11 ORX98932.1 - 0.00031 20.8 0.0 0.00038 20.5 0.0 1.1 1 0 0 1 1 1 1 Protocadherin Mid2 PF04478.12 ORX98932.1 - 0.0013 18.6 0.2 0.0017 18.2 0.2 1.1 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor TMEM154 PF15102.6 ORX98932.1 - 0.014 15.3 0.1 0.018 15.0 0.1 1.2 1 0 0 1 1 1 0 TMEM154 protein family SIT PF15330.6 ORX98932.1 - 0.015 15.7 0.0 0.022 15.2 0.0 1.3 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT SKG6 PF08693.10 ORX98932.1 - 0.017 14.5 0.6 0.034 13.5 0.6 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Amnionless PF14828.6 ORX98932.1 - 0.053 12.3 0.0 0.054 12.3 0.0 1.1 1 0 0 1 1 1 0 Amnionless EphA2_TM PF14575.6 ORX98932.1 - 0.054 14.4 0.5 0.074 13.9 0.0 1.5 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Syndecan PF01034.20 ORX98932.1 - 0.061 13.2 1.3 0.061 13.2 1.3 1.6 2 0 0 2 2 2 0 Syndecan domain DUF2207 PF09972.9 ORX98932.1 - 0.067 12.0 0.0 0.075 11.8 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) CcmD PF04995.14 ORX98932.1 - 1.2 9.3 5.2 16 5.7 1.5 2.3 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) EamA PF00892.20 ORX98933.1 - 0.00097 19.3 7.7 0.00097 19.3 7.7 2.2 2 0 0 2 2 2 2 EamA-like transporter family DUF1077 PF06417.12 ORX98933.1 - 0.079 13.0 1.7 11 6.1 0.1 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1077) Beta-lactamase PF00144.24 ORX98934.1 - 5.7e-11 42.2 0.0 7.1e-11 41.9 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase DUF5527 PF17665.1 ORX98934.1 - 0.062 12.8 0.1 0.17 11.4 0.0 1.7 1 1 1 2 2 2 0 Family of unknown function (DUF5527) Beta-lactamase PF00144.24 ORX98935.1 - 1.4e-13 50.8 0.0 1.7e-13 50.6 0.0 1.0 1 0 0 1 1 1 1 Beta-lactamase Ifi-6-16 PF06140.13 ORX98939.1 - 1.2e-08 34.8 16.9 1.7e-08 34.3 16.9 1.2 1 0 0 1 1 1 1 Interferon-induced 6-16 family EVE PF01878.18 ORX98940.1 - 5.8e-48 162.6 0.0 9.8e-48 161.8 0.0 1.4 1 0 0 1 1 1 1 EVE domain Glyco_hydro_61 PF03443.14 ORX98941.1 - 5.2e-51 173.5 0.1 6.9e-51 173.1 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 BACON PF13004.7 ORX98941.1 - 0.64 10.1 7.2 0.26 11.3 3.4 2.3 2 1 0 2 2 2 0 Putative binding domain, N-terminal CDH-cyt PF16010.5 ORX98942.1 - 1.3e-43 148.8 8.0 1.6e-43 148.5 8.0 1.1 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase DUF2112 PF09885.9 ORX98942.1 - 0.065 13.3 0.1 0.14 12.2 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2112) ABC2_membrane_3 PF12698.7 ORX98943.1 - 0.028 13.6 0.0 0.04 13.0 0.0 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein Pkinase PF00069.25 ORX98944.1 - 2e-15 56.9 0.0 5.1e-15 55.6 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX98944.1 - 0.00016 21.0 0.0 0.00029 20.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase RACo_linker PF17650.1 ORX98944.1 - 0.14 12.1 0.1 2.5 8.0 0.0 2.7 2 0 0 2 2 2 0 RACo linker region GFO_IDH_MocA PF01408.22 ORX98945.1 - 0.00047 21.0 0.0 0.00084 20.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold KilA-N PF04383.13 ORX98947.1 - 0.17 11.8 0.1 0.37 10.7 0.1 1.5 1 0 0 1 1 1 0 KilA-N domain NAD_binding_8 PF13450.6 ORX98949.1 - 4.8e-12 45.9 0.0 1e-11 44.9 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 ORX98949.1 - 1.8e-11 44.0 0.0 3.6e-11 43.0 0.0 1.6 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Thi4 PF01946.17 ORX98949.1 - 5e-06 25.9 0.0 8.2e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 ORX98949.1 - 1.7e-05 24.1 0.0 3.1e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 ORX98949.1 - 1.8e-05 24.1 0.0 2.9e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 ORX98949.1 - 2.2e-05 23.9 0.0 3.7e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 ORX98949.1 - 2.4e-05 23.2 0.3 3.5e-05 22.7 0.3 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.14 ORX98949.1 - 0.00013 21.4 0.0 0.00018 20.9 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 ORX98949.1 - 0.00014 21.4 0.0 0.00022 20.7 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 ORX98949.1 - 0.00037 19.7 0.1 0.0046 16.1 0.1 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A DAO PF01266.24 ORX98949.1 - 0.0022 17.6 0.0 0.0039 16.8 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 ORX98949.1 - 0.1 11.9 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DJ-1_PfpI PF01965.24 ORX98950.1 - 8e-13 48.5 0.0 1.5e-12 47.7 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family Aldo_ket_red PF00248.21 ORX98951.1 - 1.8e-25 89.7 0.0 2.1e-25 89.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family CorA PF01544.18 ORX98952.1 - 1.1e-05 24.9 0.1 2.4e-05 23.8 0.1 1.5 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein EMP70 PF02990.16 ORX98952.1 - 0.12 11.0 0.1 0.19 10.4 0.1 1.2 1 0 0 1 1 1 0 Endomembrane protein 70 GFO_IDH_MocA PF01408.22 ORX98953.1 - 0.001 19.9 0.1 0.0014 19.4 0.1 1.1 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold YbbR PF07949.12 ORX98953.1 - 0.1 13.0 0.0 0.13 12.6 0.0 1.2 1 0 0 1 1 1 0 YbbR-like protein DUF2148 PF09918.9 ORX98953.1 - 2.6 8.2 4.5 0.49 10.5 0.3 1.9 2 1 0 2 2 2 0 Uncharacterized protein containing a ferredoxin domain (DUF2148) SGL PF08450.12 ORX98954.1 - 5.5e-21 75.3 0.0 7.4e-21 74.8 0.0 1.2 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 ORX98954.1 - 0.0015 18.7 0.0 0.0037 17.4 0.0 1.7 1 1 0 1 1 1 1 Arylesterase Str_synth PF03088.16 ORX98954.1 - 0.0037 17.3 0.0 0.019 15.1 0.0 2.2 3 1 0 3 3 3 1 Strictosidine synthase Methyltransf_23 PF13489.6 ORX98955.1 - 8.5e-11 42.0 0.0 1.4e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORX98955.1 - 0.00012 22.7 0.0 0.00023 21.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORX98955.1 - 0.00033 21.3 0.0 0.00068 20.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain SCNM1_acidic PF15805.5 ORX98955.1 - 0.15 11.8 0.3 0.15 11.8 0.3 2.1 3 0 0 3 3 3 0 Acidic C-terminal region of sodium channel modifier 1 SCNM1 Methyltransf_11 PF08241.12 ORX98955.1 - 0.22 12.2 0.0 0.42 11.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain ABC2_membrane PF01061.24 ORX98957.1 - 1.2e-33 116.4 6.1 1.2e-33 116.4 6.1 1.8 2 0 0 2 2 2 1 ABC-2 type transporter PDR_CDR PF06422.12 ORX98957.1 - 2.6e-22 78.5 0.0 9.4e-22 76.7 0.0 2.0 1 0 0 1 1 1 1 CDR ABC transporter ABC_tran PF00005.27 ORX98957.1 - 2.6e-11 44.2 0.0 4.9e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter TPR_10 PF13374.6 ORX99018.1 - 0.0084 15.9 0.0 0.011 15.6 0.0 1.2 1 0 0 1 1 1 1 Tetratricopeptide repeat Fungal_trans PF04082.18 ORX99020.1 - 1e-13 51.0 0.1 1.7e-13 50.3 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORX99020.1 - 4.8e-07 29.8 6.5 8.5e-07 29.0 6.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_7 PF00840.20 ORX99021.1 - 6.3e-204 677.6 25.0 7.1e-204 677.4 25.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Glyco_hydro_61 PF03443.14 ORX99022.1 - 1.3e-44 152.6 0.1 1.6e-44 152.3 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 p450 PF00067.22 ORX99023.1 - 2.3e-25 89.3 0.0 2.3e-24 86.0 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 Astacin PF01400.24 ORX99024.1 - 4.8e-18 65.5 0.0 8.9e-18 64.6 0.0 1.5 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) DUF4215 PF13948.6 ORX99024.1 - 4e-08 33.6 8.4 4e-08 33.6 8.4 3.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4215) EGF_3 PF12947.7 ORX99024.1 - 0.0016 18.6 3.4 0.0076 16.4 3.4 2.2 1 0 0 1 1 1 1 EGF domain Reprolysin_5 PF13688.6 ORX99024.1 - 0.019 15.1 0.1 0.041 14.0 0.1 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 ORX99024.1 - 0.051 14.1 0.0 0.092 13.3 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 ORX99024.1 - 0.079 12.8 0.2 0.15 11.9 0.2 1.4 1 0 0 1 1 1 0 Matrixin DUF4953 PF16313.5 ORX99024.1 - 0.43 9.7 0.8 0.59 9.3 0.8 1.1 1 0 0 1 1 1 0 Met-zincin Pro-kuma_activ PF09286.11 ORX99025.1 - 2.4e-18 66.8 0.0 8.3e-18 65.0 0.0 1.9 1 1 1 2 2 2 1 Pro-kumamolisin, activation domain Form_Nir_trans PF01226.17 ORX99026.1 - 3.5e-32 111.6 17.4 5.2e-18 65.3 11.8 2.1 1 1 1 2 2 2 2 Formate/nitrite transporter DUF202 PF02656.15 ORX99026.1 - 7 7.2 7.2 14 6.2 1.3 3.0 2 2 0 2 2 2 0 Domain of unknown function (DUF202) GCV_T PF01571.21 ORX99027.1 - 8.4e-82 274.4 0.0 1.1e-81 274.0 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 ORX99027.1 - 4.1e-23 81.1 0.7 9.3e-23 80.0 0.2 1.8 2 0 0 2 2 2 1 Glycine cleavage T-protein C-terminal barrel domain DUF3659 PF12396.8 ORX99027.1 - 0.031 14.2 0.4 0.11 12.4 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3659) V-ATPase_C PF03223.15 ORX99028.1 - 2.6e-129 431.8 0.6 3e-129 431.7 0.6 1.0 1 0 0 1 1 1 1 V-ATPase subunit C TFIID_20kDa PF03847.13 ORX99028.1 - 0.11 13.0 0.0 18 5.9 0.0 2.7 2 0 0 2 2 2 0 Transcription initiation factor TFIID subunit A DUF5364 PF17322.2 ORX99028.1 - 0.23 11.7 5.8 1.8 8.9 0.6 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5364) AMP-binding PF00501.28 ORX99029.1 - 2.1e-75 253.9 0.0 2.8e-75 253.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORX99029.1 - 0.00012 23.0 0.0 0.00022 22.1 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Aldedh PF00171.22 ORX99030.1 - 4.2e-186 619.0 2.7 4.7e-186 618.8 2.7 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 ORX99030.1 - 0.21 11.0 0.1 13 5.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) FoP_duplication PF13865.6 ORX99031.1 - 6.2e-06 26.7 9.1 9.6e-06 26.1 9.1 1.4 1 1 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 RRM_1 PF00076.22 ORX99031.1 - 0.00027 20.7 0.0 0.00045 20.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 ORX99031.1 - 0.0032 17.3 0.0 0.005 16.7 0.0 1.3 1 0 0 1 1 1 1 Occluded RNA-recognition motif RE_Bsp6I PF09504.10 ORX99031.1 - 0.11 12.1 0.0 0.15 11.6 0.0 1.1 1 0 0 1 1 1 0 Bsp6I restriction endonuclease Clathrin PF00637.20 ORX99032.1 - 5.5e-22 78.2 2.1 1.4e-19 70.4 1.7 2.9 3 0 0 3 3 3 1 Region in Clathrin and VPS VPS11_C PF12451.8 ORX99032.1 - 2e-19 69.5 0.1 5.9e-19 68.0 0.1 1.9 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal zf-C3H2C3 PF17122.5 ORX99032.1 - 4.3e-06 26.7 7.2 9.8e-06 25.5 7.2 1.6 1 0 0 1 1 1 1 Zinc-finger zf-C3HC4_2 PF13923.6 ORX99032.1 - 4.9e-06 26.3 6.8 1e-05 25.3 6.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORX99032.1 - 5.7e-05 23.4 6.7 0.00011 22.5 6.7 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 ORX99032.1 - 7e-05 22.7 5.1 0.00013 21.8 5.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 ORX99032.1 - 0.00024 21.0 4.4 0.00024 21.0 4.4 1.8 2 0 0 2 2 1 1 RING-type zinc-finger TPR_11 PF13414.6 ORX99032.1 - 0.00025 20.6 0.4 0.0015 18.2 0.1 2.5 2 0 0 2 2 2 1 TPR repeat zf-ANAPC11 PF12861.7 ORX99032.1 - 0.0011 19.0 1.2 0.0026 17.8 1.2 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 ORX99032.1 - 0.0079 16.1 6.1 0.015 15.2 6.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 ORX99032.1 - 0.0082 16.4 3.8 0.021 15.1 3.8 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain TPR_14 PF13428.6 ORX99032.1 - 0.0085 16.8 0.0 5.8 8.0 0.0 4.0 2 0 0 2 2 2 1 Tetratricopeptide repeat DUF4810 PF16068.5 ORX99032.1 - 0.042 14.4 0.1 15 6.2 0.1 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4810) TPR_8 PF13181.6 ORX99032.1 - 0.047 13.9 2.0 0.43 10.9 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Vps8 PF12816.7 ORX99032.1 - 0.079 12.5 0.5 0.38 10.2 0.1 2.2 2 0 0 2 2 2 0 Golgi CORVET complex core vacuolar protein 8 zf-C3HC4_4 PF15227.6 ORX99032.1 - 0.21 11.8 6.7 0.43 10.8 6.7 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.5 ORX99032.1 - 0.44 10.3 4.9 1.3 8.8 4.9 1.8 1 0 0 1 1 1 0 RING-like zinc finger zf-Nse PF11789.8 ORX99032.1 - 0.5 10.2 4.1 1.2 9.0 4.1 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit ANAPC3 PF12895.7 ORX99032.1 - 0.52 10.6 5.7 24 5.2 0.9 3.7 2 2 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 PHD PF00628.29 ORX99032.1 - 2.4 8.1 5.8 5.3 7.0 5.8 1.6 1 0 0 1 1 1 0 PHD-finger zf-C3HC4_3 PF13920.6 ORX99032.1 - 2.8 7.9 4.8 5 7.1 4.8 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TPR_19 PF14559.6 ORX99032.1 - 4.5 7.8 5.9 10 6.7 0.3 3.6 4 0 0 4 4 3 0 Tetratricopeptide repeat Prok-RING_4 PF14447.6 ORX99032.1 - 5.1 7.1 6.1 11 6.0 6.1 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Glyco_hydro_79C PF16862.5 ORX99033.1 - 8e-21 74.9 0.2 2.6e-20 73.2 0.2 1.9 1 0 0 1 1 1 1 Glycosyl hydrolase family 79 C-terminal beta domain Git3 PF11710.8 ORX99035.1 - 1.6e-21 77.0 13.1 2.8e-21 76.2 13.1 1.3 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.21 ORX99035.1 - 6.5e-11 42.0 2.8 8.4e-11 41.7 2.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) GPR_Gpa2_C PF11970.8 ORX99035.1 - 2.1e-07 30.9 0.3 2.1e-07 30.9 0.3 2.2 2 1 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term 7TM_GPCR_Srsx PF10320.9 ORX99035.1 - 0.00016 21.2 1.8 0.00023 20.6 1.8 1.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx DUF2104 PF09877.9 ORX99035.1 - 9.4 6.6 8.8 1.3 9.4 0.1 3.2 4 0 0 4 4 4 0 Predicted membrane protein (DUF2104) PXA PF02194.15 ORX99036.1 - 1.1e-48 165.6 0.2 1.4e-47 162.0 0.0 2.7 3 0 0 3 3 3 1 PXA domain Nexin_C PF08628.12 ORX99036.1 - 4.2e-25 88.5 0.1 1.2e-24 87.0 0.1 1.9 1 0 0 1 1 1 1 Sorting nexin C terminal PX PF00787.24 ORX99036.1 - 1.5e-20 73.3 0.3 4.5e-20 71.7 0.3 1.9 1 0 0 1 1 1 1 PX domain RGS PF00615.19 ORX99036.1 - 7.9e-10 39.0 0.0 2.3e-09 37.6 0.0 1.9 1 0 0 1 1 1 1 Regulator of G protein signaling domain Mod_r PF07200.13 ORX99036.1 - 0.13 12.4 2.8 0.83 9.7 2.8 2.4 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein RRP36 PF06102.12 ORX99036.1 - 1 9.3 6.1 0.22 11.4 1.0 2.3 2 0 0 2 2 2 0 rRNA biogenesis protein RRP36 adh_short PF00106.25 ORX99037.1 - 1.4e-24 86.7 0.0 1.9e-24 86.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORX99037.1 - 2.1e-15 56.9 0.0 2.8e-15 56.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORX99037.1 - 7.5e-08 32.5 0.0 1e-07 32.0 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ORX99037.1 - 0.07 12.6 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Aa_trans PF01490.18 ORX99073.1 - 2e-33 115.7 26.5 4.3e-19 68.5 12.2 2.0 1 1 1 2 2 2 2 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 ORX99073.1 - 0.0009 18.4 8.7 0.0009 18.4 8.7 2.0 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family DUF2105 PF09878.9 ORX99073.1 - 0.015 15.0 5.4 0.015 15.0 5.4 2.0 2 1 0 2 2 2 0 Predicted membrane protein (DUF2105) F-box PF00646.33 ORX99074.1 - 0.12 12.3 0.2 0.12 12.3 0.2 2.3 3 0 0 3 3 3 0 F-box domain Cpn60_TCP1 PF00118.24 ORX99075.1 - 2.4e-153 511.3 6.6 2.8e-153 511.1 6.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FtsA PF14450.6 ORX99075.1 - 0.23 11.9 1.4 0.45 11.0 0.9 2.0 1 1 0 1 1 1 0 Cell division protein FtsA F-box-like PF12937.7 ORX99076.1 - 1.7e-08 34.2 0.3 3.6e-08 33.2 0.3 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORX99076.1 - 8e-05 22.4 0.6 0.00015 21.5 0.6 1.5 1 0 0 1 1 1 1 F-box domain Mito_carr PF00153.27 ORX99077.1 - 2.3e-63 210.1 0.3 2.1e-20 72.4 0.0 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 ORX99077.1 - 0.0097 15.1 0.4 0.2 10.8 0.1 2.4 2 0 0 2 2 2 1 Gammaproteobacterial serine protease YtxH PF12732.7 ORX99077.1 - 0.024 15.1 0.1 0.1 13.2 0.0 2.0 2 0 0 2 2 2 0 YtxH-like protein DUF4148 PF13663.6 ORX99077.1 - 1.1 9.6 5.4 0.16 12.2 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) Lipocalin_2 PF08212.12 ORX99078.1 - 0.25 11.2 0.5 12 5.9 0.1 2.1 1 1 1 2 2 2 0 Lipocalin-like domain Pkinase_Tyr PF07714.17 ORX99079.1 - 4e-05 23.0 0.2 4.9e-05 22.7 0.2 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 ORX99079.1 - 6.8e-05 22.4 0.1 8.1e-05 22.1 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Cypo_polyhedrin PF05865.11 ORX99079.1 - 0.18 11.1 0.0 0.18 11.1 0.0 1.0 1 0 0 1 1 1 0 Cypovirus polyhedrin protein AAA PF00004.29 ORX99080.1 - 2.5e-05 24.7 0.0 2.8e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) 2OG-FeII_Oxy PF03171.20 ORX99126.1 - 0.011 16.1 0.1 0.041 14.4 0.0 1.7 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily Pkinase PF00069.25 ORX99129.1 - 0.0044 16.4 0.5 0.014 14.8 0.5 1.7 1 1 0 1 1 1 1 Protein kinase domain EKLF_TAD2 PF16833.5 ORX99129.1 - 0.15 12.1 0.6 2.5 8.2 0.0 2.2 2 0 0 2 2 2 0 Erythroid krueppel-like transcription factor, transactivation 2 DUF3435 PF11917.8 ORX99130.1 - 1.7e-09 37.1 0.5 1.8e-09 37.1 0.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) Lon_C PF05362.13 ORX99135.1 - 9.1e-64 214.8 0.0 1.8e-63 213.8 0.0 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.29 ORX99135.1 - 1.2e-21 77.5 0.0 3.2e-21 76.1 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) LON_substr_bdg PF02190.16 ORX99135.1 - 7.6e-13 48.8 0.2 1.7e-12 47.7 0.2 1.6 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA_2 PF07724.14 ORX99135.1 - 1.5e-06 28.5 0.0 5.4e-06 26.6 0.0 2.0 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 ORX99135.1 - 5.7e-06 26.4 0.0 1.4e-05 25.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.6 ORX99135.1 - 1.8e-05 24.5 0.0 4.6e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_22 PF13401.6 ORX99135.1 - 2.5e-05 24.6 0.1 0.00062 20.1 0.1 2.6 1 1 0 1 1 1 1 AAA domain AAA_PrkA PF08298.11 ORX99135.1 - 4.3e-05 22.6 0.0 8.5e-05 21.6 0.0 1.4 1 0 0 1 1 1 1 PrkA AAA domain RuvB_N PF05496.12 ORX99135.1 - 4.3e-05 23.3 0.1 0.00085 19.1 0.0 2.7 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 ORX99135.1 - 0.00068 20.1 0.5 0.0064 16.9 0.0 2.6 2 1 1 3 3 3 1 AAA ATPase domain AAA_14 PF13173.6 ORX99135.1 - 0.0082 16.2 0.0 0.02 15.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 ORX99135.1 - 0.0092 15.7 0.0 0.066 12.9 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_30 PF13604.6 ORX99135.1 - 0.032 14.0 0.0 0.076 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain SKI PF01202.22 ORX99135.1 - 0.038 14.1 0.1 0.4 10.8 0.0 2.4 2 0 0 2 2 2 0 Shikimate kinase RsgA_GTPase PF03193.16 ORX99135.1 - 0.095 12.6 0.0 0.36 10.7 0.0 2.0 1 0 0 1 1 1 0 RsgA GTPase AAA_7 PF12775.7 ORX99135.1 - 0.098 12.2 0.0 0.24 10.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region F-box-like_2 PF13013.6 ORX99135.1 - 0.1 12.6 0.0 0.31 11.0 0.0 1.8 1 0 0 1 1 1 0 F-box-like domain AAA_33 PF13671.6 ORX99135.1 - 0.11 12.6 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 ORX99135.1 - 0.12 13.0 0.0 0.12 13.0 0.0 3.1 4 0 0 4 4 2 0 AAA domain DNTTIP1_dimer PF18192.1 ORX99135.1 - 0.14 12.6 1.2 9 6.7 0.1 3.2 2 2 0 2 2 2 0 DNTTIP1 dimerisation domain RNA_helicase PF00910.22 ORX99135.1 - 0.14 12.5 0.0 0.41 11.0 0.0 1.9 1 0 0 1 1 1 0 RNA helicase Latrophilin PF02354.16 ORX99135.1 - 0.25 10.4 0.7 0.54 9.3 0.7 1.5 1 0 0 1 1 1 0 Latrophilin Cytoplasmic C-terminal region Pkinase PF00069.25 ORX99137.1 - 5.8e-13 48.8 0.1 1.3e-11 44.4 0.1 2.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX99137.1 - 4.3e-11 42.6 0.0 7.5e-10 38.5 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Methyltransf_23 PF13489.6 ORX99139.1 - 4.7e-06 26.5 0.0 6.7e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORX99139.1 - 4.9e-06 27.2 0.0 1.3e-05 25.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 ORX99139.1 - 2.9e-05 23.9 0.0 5.7e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 ORX99139.1 - 0.0019 18.0 0.0 0.0048 16.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 ORX99139.1 - 0.0033 17.1 0.0 0.0057 16.3 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_12 PF08242.12 ORX99139.1 - 0.0046 17.7 0.0 0.01 16.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 ORX99139.1 - 0.015 14.6 0.0 0.023 14.0 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 ORX99139.1 - 0.023 14.1 0.0 0.035 13.4 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 ORX99139.1 - 0.084 13.5 0.0 0.17 12.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.19 ORX99139.1 - 0.17 12.0 0.0 0.26 11.4 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Na_Ca_ex PF01699.24 ORX99140.1 - 4.5e-28 98.1 25.4 1.7e-14 54.0 12.5 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF443 PF04276.12 ORX99140.1 - 0.015 15.1 0.7 0.033 14.0 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF443) Ribosomal_S17e PF00833.18 ORX99141.1 - 2e-59 198.8 0.8 2.4e-59 198.6 0.8 1.1 1 0 0 1 1 1 1 Ribosomal S17 GUCT PF08152.12 ORX99141.1 - 0.089 13.1 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 GUCT (NUC152) domain Glyco_transf_20 PF00982.21 ORX99146.1 - 6.6e-30 104.2 0.2 2.8e-16 59.2 0.1 2.0 1 1 1 2 2 2 2 Glycosyltransferase family 20 OmpH PF03938.14 ORX99147.1 - 0.56 10.5 9.6 0.75 10.1 9.6 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF3433 PF11915.8 ORX99149.1 - 1.5e-27 95.9 24.5 2.9e-17 62.9 4.5 3.8 4 0 0 4 4 4 2 Protein of unknown function (DUF3433) CrgA PF06781.12 ORX99149.1 - 2.4 8.3 5.7 1.3 9.1 0.0 3.1 3 0 0 3 3 3 0 Cell division protein CrgA Abhydrolase_4 PF08386.10 ORX99201.1 - 3.7e-19 68.8 0.0 8.3e-19 67.6 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.20 ORX99201.1 - 1.8e-18 67.1 0.0 3.5e-18 66.2 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold FAD_binding_4 PF01565.23 ORX99202.1 - 3.2e-13 49.6 1.1 6.3e-13 48.7 0.6 1.8 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 ORX99202.1 - 7.9e-09 35.5 0.1 1.6e-08 34.5 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like MIP PF00230.20 ORX99203.1 - 0.15 11.7 0.0 0.17 11.6 0.0 1.1 1 0 0 1 1 1 0 Major intrinsic protein GPI-anchored PF10342.9 ORX99205.1 - 1.9e-05 25.4 0.0 0.00015 22.4 0.0 2.3 1 1 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family RNase_T PF00929.24 ORX99206.1 - 1e-25 91.2 0.0 1.2e-25 91.0 0.0 1.0 1 0 0 1 1 1 1 Exonuclease DNA_pol_B PF00136.21 ORX99207.1 - 6.5e-114 381.2 0.1 1.1e-113 380.4 0.1 1.4 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.10 ORX99207.1 - 3.9e-63 212.5 0.0 7.8e-63 211.6 0.0 1.5 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.19 ORX99207.1 - 5.6e-46 157.2 0.0 1.6e-45 155.7 0.0 1.8 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.8 ORX99207.1 - 2.5e-26 91.6 11.7 2.3e-25 88.4 7.2 2.7 2 0 0 2 2 2 2 DNA polymerase alpha subunit p180 N terminal DNA_pol_B_2 PF03175.13 ORX99207.1 - 0.03 13.2 0.0 0.069 12.0 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral Aminotran_5 PF00266.19 ORX99208.1 - 4.6e-10 39.0 0.0 7.2e-08 31.8 0.0 2.8 2 2 1 3 3 3 2 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 ORX99208.1 - 0.011 14.3 0.0 0.018 13.6 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme DUF5427 PF10310.9 ORX99208.1 - 1.2 8.0 4.1 0.57 9.1 1.0 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5427) Fe-S_biosyn PF01521.20 ORX99209.1 - 1.8e-13 50.6 0.0 2.4e-13 50.2 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis GatB_Yqey PF02637.18 ORX99210.1 - 0.03 14.2 0.3 0.039 13.8 0.3 1.1 1 0 0 1 1 1 0 GatB domain CDH1_2_SANT_HL1 PF18375.1 ORX99210.1 - 0.4 11.4 4.1 0.34 11.6 1.2 2.0 1 1 1 2 2 2 0 CDH1/2 SANT-Helical linker 1 HMG-CoA_red PF00368.18 ORX99211.1 - 3.1e-87 293.0 0.6 3.8e-87 292.7 0.6 1.0 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HET PF06985.11 ORX99212.1 - 1.6e-32 112.9 0.1 3.4e-32 111.8 0.1 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF2046 PF09755.9 ORX99213.1 - 0.01 15.1 0.3 0.14 11.3 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) GreA_GreB_N PF03449.15 ORX99213.1 - 0.48 10.6 5.8 0.14 12.3 1.7 1.9 2 0 0 2 2 2 0 Transcription elongation factor, N-terminal ATG16 PF08614.11 ORX99213.1 - 1.6 8.9 8.4 0.29 11.3 0.2 2.6 3 0 0 3 3 3 0 Autophagy protein 16 (ATG16) Paf67 PF10255.9 ORX99214.1 - 3.4e-160 533.5 0.0 4e-160 533.3 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.17 ORX99214.1 - 0.033 14.3 0.0 0.16 12.2 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat EthD PF07110.11 ORX99215.1 - 2e-19 70.5 0.0 2.6e-19 70.1 0.0 1.2 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 ORX99215.1 - 7.4e-06 26.4 0.1 6e-05 23.5 0.1 1.9 1 1 0 1 1 1 1 Methylmuconolactone methyl-isomerase CN_hydrolase PF00795.22 ORX99216.1 - 2e-33 115.8 0.0 2.7e-33 115.4 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase EthD PF07110.11 ORX99217.1 - 8.2e-12 46.1 0.0 1e-11 45.8 0.0 1.1 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 ORX99217.1 - 0.0018 18.7 0.1 0.0057 17.1 0.1 1.9 1 1 0 1 1 1 1 Methylmuconolactone methyl-isomerase BCS1_N PF08740.11 ORX99219.1 - 6.9e-43 146.8 0.0 1.1e-42 146.2 0.0 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 ORX99219.1 - 1.3e-18 67.7 0.0 2.5e-18 66.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 ORX99219.1 - 9.6e-05 21.7 0.0 0.00016 21.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.6 ORX99219.1 - 0.00022 21.7 0.1 0.0012 19.3 0.0 2.3 2 1 1 3 3 2 1 AAA ATPase domain AAA_21 PF13304.6 ORX99219.1 - 0.0025 17.7 0.0 0.0045 16.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_7 PF12775.7 ORX99219.1 - 0.0026 17.3 0.0 0.0051 16.3 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_5 PF07728.14 ORX99219.1 - 0.0027 17.7 0.0 0.0096 15.9 0.0 2.0 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 ORX99219.1 - 0.0038 17.8 0.0 0.018 15.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 ORX99219.1 - 0.0048 16.6 0.0 0.13 12.0 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.6 ORX99219.1 - 0.0063 16.1 0.0 0.03 13.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain PPV_E1_C PF00519.17 ORX99219.1 - 0.0074 15.2 0.0 0.02 13.7 0.0 1.7 2 0 0 2 2 2 1 Papillomavirus helicase AAA_29 PF13555.6 ORX99219.1 - 0.014 15.1 0.0 0.085 12.6 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain RNA_helicase PF00910.22 ORX99219.1 - 0.015 15.7 0.0 0.081 13.3 0.0 2.3 2 0 0 2 2 2 0 RNA helicase AAA_33 PF13671.6 ORX99219.1 - 0.059 13.5 0.0 0.26 11.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 ORX99219.1 - 0.061 12.7 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_28 PF13521.6 ORX99219.1 - 0.064 13.5 0.0 0.36 11.1 0.0 2.2 3 0 0 3 3 3 0 AAA domain AAA_22 PF13401.6 ORX99219.1 - 0.075 13.3 0.0 0.21 11.9 0.0 1.8 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 ORX99219.1 - 0.076 13.1 0.0 0.22 11.6 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.27 ORX99219.1 - 0.087 13.3 0.0 0.17 12.4 0.0 1.6 1 0 0 1 1 1 0 ABC transporter RsgA_GTPase PF03193.16 ORX99219.1 - 0.15 11.9 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase GTSE1_N PF15259.6 ORX99219.1 - 0.2 11.8 0.0 0.35 11.0 0.0 1.3 1 0 0 1 1 1 0 G-2 and S-phase expressed 1 OPT PF03169.15 ORX99220.1 - 9.3e-200 665.4 30.5 1.1e-199 665.1 30.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Pkinase PF00069.25 ORX99221.1 - 9.5e-41 139.9 0.0 1.5e-40 139.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX99221.1 - 3.9e-24 85.3 0.0 7.5e-24 84.4 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORX99221.1 - 0.0001 21.2 0.0 0.00022 20.1 0.0 1.4 1 1 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 ORX99221.1 - 0.0019 17.8 0.0 0.0032 17.1 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 ORX99221.1 - 0.11 11.8 0.3 0.41 10.0 0.1 2.0 2 1 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family FA_hydroxylase PF04116.13 ORX99222.1 - 1e-27 97.1 16.5 1e-27 97.1 16.5 1.9 2 1 1 3 3 3 1 Fatty acid hydroxylase superfamily Oxysterol_BP PF01237.18 ORX99223.1 - 6.1e-65 219.5 5.7 6.1e-58 196.4 0.0 2.0 1 1 1 2 2 2 2 Oxysterol-binding protein F-box-like PF12937.7 ORX99224.1 - 0.0057 16.5 0.2 0.014 15.3 0.2 1.7 1 0 0 1 1 1 1 F-box-like Aldo_ket_red PF00248.21 ORX99226.1 - 2.4e-51 174.7 0.0 6.4e-51 173.3 0.0 1.6 1 1 0 1 1 1 1 Aldo/keto reductase family ScsC_N PF18312.1 ORX99226.1 - 0.15 11.9 0.0 19 5.2 0.0 2.4 2 0 0 2 2 2 0 Copper resistance protein ScsC N-terminal domain Hydrolase_6 PF13344.6 ORX99227.1 - 1.9e-22 79.3 0.0 4e-22 78.2 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ORX99227.1 - 5.2e-19 68.1 0.0 2.1e-18 66.1 0.0 2.1 2 1 0 2 2 2 1 HAD-hyrolase-like HAD_2 PF13419.6 ORX99227.1 - 0.026 14.6 0.0 0.28 11.3 0.0 2.2 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ORX99227.1 - 0.031 14.6 0.1 2.8 8.2 0.0 2.6 2 1 0 3 3 3 0 haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 ORX99227.1 - 0.15 11.7 0.0 0.29 10.7 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial PGP phosphatase CUE PF02845.16 ORX99229.1 - 0.00052 19.7 0.0 0.00087 18.9 0.0 1.4 1 0 0 1 1 1 1 CUE domain zf-C3HC4_4 PF15227.6 ORX99230.1 - 0.029 14.5 0.1 0.029 14.5 0.1 2.2 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING An_peroxidase PF03098.15 ORX99277.1 - 1.3e-38 132.9 0.0 8.8e-24 84.0 0.0 3.1 1 1 2 3 3 3 3 Animal haem peroxidase Steroid_dh PF02544.16 ORX99278.1 - 6.4e-35 120.3 0.4 8.8e-35 119.9 0.4 1.2 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 ORX99278.1 - 0.00018 21.1 0.3 0.00023 20.7 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.13 ORX99278.1 - 0.0002 21.7 1.2 0.00054 20.3 0.6 2.0 2 1 0 2 2 2 1 Phospholipid methyltransferase ATE_C PF04377.15 ORX99279.1 - 5.7e-47 159.7 1.7 1e-46 158.9 1.7 1.4 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 ORX99279.1 - 1.6e-26 92.5 3.6 2.7e-25 88.6 3.6 2.3 2 0 0 2 2 2 1 Arginine-tRNA-protein transferase, N terminus DUF1571 PF07608.11 ORX99279.1 - 0.075 12.5 1.1 1.7 8.1 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1571) NUDIX PF00293.28 ORX99281.1 - 5.7e-18 65.2 0.5 7.5e-18 64.8 0.5 1.1 1 0 0 1 1 1 1 NUDIX domain VasL PF12486.8 ORX99281.1 - 0.028 14.3 1.9 0.028 14.3 1.9 1.8 3 0 0 3 3 3 0 Type VI secretion system, EvfB, or VasL FAD_binding_4 PF01565.23 ORX99282.1 - 6.4e-05 22.7 0.1 0.011 15.4 0.0 2.3 1 1 1 2 2 2 2 FAD binding domain Beta-lactamase PF00144.24 ORX99283.1 - 2.6e-32 112.4 0.0 3.8e-32 111.8 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Zn_clus PF00172.18 ORX99284.1 - 6.4e-07 29.4 9.5 1.2e-06 28.5 9.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 ORX99284.1 - 0.00015 20.7 0.3 0.00025 20.0 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain V-SNARE_C PF12352.8 ORX99284.1 - 0.059 13.7 3.5 0.13 12.6 0.0 3.2 4 0 0 4 4 4 0 Snare region anchored in the vesicle membrane C-terminus FAD_binding_2 PF00890.24 ORX99285.1 - 8e-118 394.1 6.0 1e-117 393.8 6.0 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 ORX99285.1 - 9.2e-37 125.9 1.9 1.4e-36 125.3 1.9 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Thi4 PF01946.17 ORX99285.1 - 0.00018 20.8 0.5 0.091 12.0 0.1 2.4 2 0 0 2 2 2 2 Thi4 family Pyr_redox_2 PF07992.14 ORX99285.1 - 0.00043 19.6 2.4 0.0035 16.6 0.6 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 ORX99285.1 - 0.00092 18.4 2.6 0.11 11.6 2.7 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_3 PF01494.19 ORX99285.1 - 0.0026 17.1 0.6 0.0055 16.0 0.6 1.5 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 ORX99285.1 - 0.16 10.7 2.0 0.38 9.4 0.7 2.1 2 0 0 2 2 2 0 HI0933-like protein NTP_transf_4 PF13562.6 ORX99285.1 - 0.18 12.0 0.1 0.31 11.2 0.1 1.3 1 0 0 1 1 1 0 Sugar nucleotidyl transferase Pyr_redox_3 PF13738.6 ORX99285.1 - 1.2 8.3 3.3 1.3 8.3 1.6 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Tetraspanin PF00335.20 ORX99286.1 - 0.00095 18.9 1.7 0.0025 17.5 0.5 2.2 2 1 1 3 3 3 2 Tetraspanin family SCIMP PF15050.6 ORX99287.1 - 1.6 9.2 4.6 1.6 9.2 2.5 2.1 1 1 1 2 2 2 0 SCIMP protein GMC_oxred_N PF00732.19 ORX99288.1 - 2.1e-40 138.9 0.0 2.7e-25 89.4 0.0 2.2 1 1 1 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.13 ORX99288.1 - 1.2e-28 100.4 0.0 2e-28 99.7 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_3 PF13738.6 ORX99288.1 - 6.2e-05 22.4 0.0 0.0082 15.4 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORX99288.1 - 7.9e-05 22.8 0.1 0.00028 21.1 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 ORX99288.1 - 0.00059 19.0 0.0 0.029 13.5 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 ORX99288.1 - 0.00079 18.7 0.0 0.3 10.3 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ORX99288.1 - 0.00082 19.0 0.2 0.0076 15.9 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 ORX99288.1 - 0.011 14.5 0.2 0.037 12.7 0.0 1.9 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.17 ORX99288.1 - 0.02 14.2 0.0 0.089 12.0 0.1 1.9 2 0 0 2 2 2 0 Thi4 family TrkA_N PF02254.18 ORX99288.1 - 0.043 14.1 0.2 0.097 12.9 0.2 1.6 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_9 PF13454.6 ORX99288.1 - 0.065 13.2 0.2 0.23 11.4 0.0 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 ORX99288.1 - 0.084 11.9 0.1 0.22 10.5 0.0 1.8 1 1 0 1 1 1 0 Lycopene cyclase protein Fungal_trans_2 PF11951.8 ORX99290.1 - 0.052 12.3 0.2 0.067 12.0 0.2 1.1 1 0 0 1 1 1 0 Fungal specific transcription factor domain TetR PF13972.6 ORX99291.1 - 0.039 13.7 0.0 0.097 12.4 0.0 1.6 2 0 0 2 2 2 0 Bacterial transcriptional repressor Med26_M PF15694.5 ORX99292.1 - 0.025 14.6 0.4 0.035 14.2 0.4 1.1 1 0 0 1 1 1 0 Mediator complex subunit 26 middle domain Sugar_tr PF00083.24 ORX99293.1 - 9.8e-91 304.9 27.9 1.2e-90 304.5 27.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORX99293.1 - 3.9e-17 62.2 56.6 1e-16 60.9 26.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Glycophorin_A PF01102.18 ORX99294.1 - 0.14 12.4 2.4 6.1 7.1 0.0 2.9 3 0 0 3 3 3 0 Glycophorin A DUF2207 PF09972.9 ORX99294.1 - 0.17 10.6 0.1 1.7 7.3 0.0 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Cellulase PF00150.18 ORX99296.1 - 2.7e-20 73.0 0.9 3.6e-20 72.6 0.9 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DNMT1-RFD PF12047.8 ORX99296.1 - 0.0034 17.4 0.1 0.014 15.5 0.1 2.0 2 0 0 2 2 2 1 Cytosine specific DNA methyltransferase replication foci domain Glyco_hydro_2_C PF02836.17 ORX99296.1 - 0.0068 15.6 0.3 0.015 14.4 0.3 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain AP_endonuc_2 PF01261.24 ORX99296.1 - 0.03 13.8 0.0 0.12 11.8 0.0 1.9 1 1 1 2 2 2 0 Xylose isomerase-like TIM barrel GCN5L1 PF06320.13 ORX99297.1 - 2.3e-22 79.3 3.8 2.7e-22 79.1 3.8 1.0 1 0 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) VP4_2 PF08935.10 ORX99297.1 - 0.02 15.4 0.3 0.039 14.5 0.3 1.5 1 0 0 1 1 1 0 Viral protein VP4 subunit YdaT_toxin PF06254.11 ORX99297.1 - 0.093 13.3 0.3 0.15 12.7 0.3 1.3 1 0 0 1 1 1 0 Putative bacterial toxin ydaT DUF913 PF06025.12 ORX99298.1 - 5.5e-128 427.1 0.0 5.5e-128 427.1 0.0 6.2 7 0 0 7 7 7 1 Domain of Unknown Function (DUF913) DUF908 PF06012.12 ORX99298.1 - 3.5e-104 349.1 0.0 3.5e-104 349.1 0.0 4.4 4 0 0 4 4 4 1 Domain of Unknown Function (DUF908) HECT PF00632.25 ORX99298.1 - 6.4e-93 311.6 0.0 1.1e-92 310.9 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) UBM PF14377.6 ORX99298.1 - 4.3e-30 102.2 22.3 1.3e-10 40.4 0.8 4.5 4 0 0 4 4 4 3 Ubiquitin binding region UBA PF00627.31 ORX99298.1 - 0.023 14.6 0.1 0.065 13.2 0.1 1.8 1 0 0 1 1 1 0 UBA/TS-N domain MMR1 PF08505.10 ORX99298.1 - 0.61 10.3 12.5 0.029 14.7 3.3 2.6 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein Talin_middle PF09141.10 ORX99299.1 - 0.054 13.5 3.0 0.096 12.7 3.0 1.4 1 0 0 1 1 1 0 Talin, middle domain Pkinase_fungal PF17667.1 ORX99347.1 - 1.1e-17 63.9 2.8 5.1e-10 38.7 0.1 2.5 1 1 1 2 2 2 2 Fungal protein kinase HTH_38 PF13936.6 ORX99350.1 - 0.00029 20.5 0.2 0.00042 20.0 0.2 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain Pkinase PF00069.25 ORX99351.1 - 0.00063 19.2 0.3 0.00064 19.2 0.3 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 ORX99351.1 - 0.049 13.0 0.0 0.054 12.8 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4510 PF14971.6 ORX99353.1 - 0.043 14.2 5.8 0.077 13.3 5.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4510) DDRGK PF09756.9 ORX99353.1 - 0.23 11.0 9.4 0.31 10.6 9.4 1.2 1 0 0 1 1 1 0 DDRGK domain PUMA PF15826.5 ORX99353.1 - 0.52 10.5 5.0 0.85 9.8 5.0 1.3 1 0 0 1 1 1 0 Bcl-2-binding component 3, p53 upregulated modulator of apoptosis Hep_core_N PF08290.11 ORX99354.1 - 0.024 14.6 1.2 0.044 13.7 0.3 1.8 2 0 0 2 2 2 0 Hepatitis core protein, putative zinc finger TPPII_N PF12583.8 ORX99354.1 - 0.29 11.7 1.4 6.6 7.3 0.1 2.0 1 1 1 2 2 2 0 Tripeptidyl peptidase II N terminal DUF1996 PF09362.10 ORX99400.1 - 5e-85 285.2 0.6 5e-85 285.2 0.6 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1996) WSC PF01822.19 ORX99400.1 - 3.8e-20 71.8 11.6 3.8e-20 71.8 11.6 2.8 2 0 0 2 2 2 1 WSC domain Spc7_N PF15402.6 ORX99400.1 - 4.7 5.3 12.0 6.7 4.8 12.0 1.1 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 Ribosomal_L7Ae PF01248.26 ORX99401.1 - 4e-27 93.8 0.1 4.7e-27 93.6 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 ORX99401.1 - 3.1e-05 24.1 0.2 4.7e-05 23.5 0.2 1.3 1 1 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.6 ORX99401.1 - 0.00094 19.0 0.0 0.0013 18.6 0.0 1.2 1 0 0 1 1 1 1 PELOTA RNA binding domain ATP-synt_C PF00137.21 ORX99402.1 - 4.3e-35 119.9 33.7 7e-22 77.5 14.8 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Glycophorin_A PF01102.18 ORX99402.1 - 9.4 6.5 5.5 0.71 10.1 0.4 1.6 2 0 0 2 2 2 0 Glycophorin A Piwi PF02171.17 ORX99403.1 - 1.2e-66 225.0 0.0 3.1e-66 223.7 0.0 1.7 1 0 0 1 1 1 1 Piwi domain ArgoL1 PF08699.10 ORX99403.1 - 1.5e-09 37.4 0.4 4.5e-09 35.8 0.4 1.8 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoL2 PF16488.5 ORX99403.1 - 0.0098 16.2 0.0 0.048 14.0 0.0 2.2 2 0 0 2 2 2 1 Argonaute linker 2 domain PQ-loop PF04193.14 ORX99405.1 - 1.2e-35 121.0 13.3 3.6e-18 65.1 3.4 2.4 2 0 0 2 2 2 2 PQ loop repeat YrhC PF14143.6 ORX99405.1 - 0.042 13.9 0.4 0.16 12.1 0.1 2.1 2 0 0 2 2 2 0 YrhC-like protein Pyr_redox_2 PF07992.14 ORX99407.1 - 8.5e-50 169.6 0.0 1.1e-49 169.3 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORX99407.1 - 6.7e-12 45.8 0.0 7.6e-10 39.2 0.0 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ORX99407.1 - 0.01 15.1 0.0 3.5 6.8 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FlxA PF14282.6 ORX99407.1 - 0.024 14.6 4.1 0.054 13.5 4.1 1.5 1 0 0 1 1 1 0 FlxA-like protein DUF4391 PF14335.6 ORX99407.1 - 0.14 11.9 2.9 0.22 11.2 2.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4391) NmrA PF05368.13 ORX99408.1 - 4.2e-34 118.1 0.0 5e-34 117.9 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ORX99408.1 - 2.4e-09 37.4 0.0 3.3e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 ORX99408.1 - 8.8e-05 22.1 0.0 0.01 15.3 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 ORX99408.1 - 0.016 14.2 0.0 0.022 13.8 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 ORX99408.1 - 0.049 13.5 0.0 0.083 12.8 0.0 1.3 1 0 0 1 1 1 0 KR domain DUF4093 PF13331.6 ORX99408.1 - 0.13 12.7 0.0 0.32 11.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4093) Semialdhyde_dh PF01118.24 ORX99408.1 - 0.14 12.6 0.0 0.42 11.1 0.0 1.8 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain NTP_transf_9 PF04248.12 ORX99409.1 - 4.4e-31 106.6 1.1 5.1e-31 106.4 1.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF427) Bystin PF05291.11 ORX99410.1 - 1.2e-128 428.5 0.0 1.5e-128 428.2 0.0 1.1 1 0 0 1 1 1 1 Bystin SPRY PF00622.28 ORX99411.1 - 0.00054 20.1 0.0 0.95 9.6 0.0 3.7 3 1 0 3 3 3 2 SPRY domain Pyridoxal_deC PF00282.19 ORX99413.1 - 6.4e-113 377.3 0.0 8.3e-113 376.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_1_2 PF00155.21 ORX99413.1 - 0.0017 17.6 0.0 0.0028 16.9 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II YCII PF03795.14 ORX99413.1 - 0.21 12.0 0.8 12 6.4 0.1 2.6 3 0 0 3 3 3 0 YCII-related domain Methyltransf_25 PF13649.6 ORX99414.1 - 9.2e-05 23.1 0.0 0.00035 21.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORX99414.1 - 0.00025 21.7 0.0 0.0016 19.2 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORX99414.1 - 0.00093 19.1 0.0 0.0018 18.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORX99414.1 - 0.0063 17.1 0.0 0.018 15.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 ORX99414.1 - 0.049 12.8 0.1 0.13 11.4 0.0 1.8 3 0 0 3 3 3 0 NNMT/PNMT/TEMT family Methyltransf_31 PF13847.6 ORX99414.1 - 0.076 12.8 0.0 0.17 11.7 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain MFS_1 PF07690.16 ORX99415.1 - 4e-20 72.0 29.2 4e-20 72.0 29.2 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORX99415.1 - 0.0013 17.7 0.6 0.0013 17.7 0.6 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter DHFR_1 PF00186.19 ORX99416.1 - 1.4e-27 96.3 0.0 3.7e-27 95.0 0.0 1.8 1 1 0 1 1 1 1 Dihydrofolate reductase GAIN PF16489.5 ORX99416.1 - 0.12 11.8 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 GPCR-Autoproteolysis INducing (GAIN) domain DUF3328 PF11807.8 ORX99417.1 - 7.1e-28 97.9 2.5 8.5e-28 97.6 2.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Coq4 PF05019.13 ORX99417.1 - 0.058 12.7 0.1 5.3 6.3 0.0 2.1 2 0 0 2 2 2 0 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 HET PF06985.11 ORX99419.1 - 4.6e-21 75.7 0.0 7.4e-21 75.0 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) RRM_8 PF11835.8 ORX99419.1 - 0.013 15.7 0.0 0.034 14.3 0.0 1.6 1 0 0 1 1 1 0 RRM-like domain F-box-like PF12937.7 ORX99422.1 - 8.3e-06 25.6 0.2 8.3e-06 25.6 0.2 3.2 4 0 0 4 4 4 1 F-box-like Tyr-DNA_phospho PF06087.12 ORX99423.1 - 5.7e-69 233.1 0.1 6.1e-68 229.7 0.1 2.1 1 1 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase UIM PF02809.20 ORX99423.1 - 2.5e-06 27.0 2.8 0.00014 21.5 0.6 2.5 2 0 0 2 2 2 2 Ubiquitin interaction motif Urm1 PF09138.11 ORX99424.1 - 4.2e-36 123.2 0.0 5.1e-36 122.9 0.0 1.1 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.20 ORX99424.1 - 0.01 16.4 0.0 0.016 15.8 0.0 1.4 1 0 0 1 1 1 0 ThiS family WD40 PF00400.32 ORX99425.1 - 5.7e-40 134.6 22.6 4.6e-05 24.1 0.0 11.6 12 0 0 12 12 12 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX99425.1 - 1.9e-09 37.7 5.3 0.53 10.6 0.1 7.8 6 2 2 8 8 8 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 ORX99425.1 - 0.0046 16.0 0.0 16 4.3 0.1 4.4 4 1 0 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein BBS2_Mid PF14783.6 ORX99425.1 - 0.011 15.8 0.1 1.7 8.7 0.0 4.3 6 0 0 6 6 6 0 Ciliary BBSome complex subunit 2, middle region Cytochrom_D1 PF02239.16 ORX99425.1 - 0.044 12.3 0.0 0.94 7.9 0.0 2.4 1 1 1 2 2 2 0 Cytochrome D1 heme domain ComS PF17584.2 ORX99426.1 - 0.039 13.5 2.0 0.19 11.2 2.0 2.2 1 0 0 1 1 1 0 Bacillus competence protein S Chlorovi_GP_rpt PF06598.11 ORX99427.1 - 0.44 10.6 1.5 0.63 10.2 0.0 2.0 2 0 0 2 2 2 0 Chlorovirus glycoprotein repeat Kelch_5 PF13854.6 ORX99428.1 - 0.045 13.8 0.4 6.4 6.9 0.0 2.9 3 0 0 3 3 3 0 Kelch motif Kelch_4 PF13418.6 ORX99428.1 - 0.059 13.4 2.6 6.1 6.9 0.1 3.3 3 0 0 3 3 3 0 Galactose oxidase, central domain Fmp27 PF10344.9 ORX99429.1 - 4.8e-210 700.0 0.0 6.4e-210 699.6 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial protein from FMP27 Fmp27_GFWDK PF10347.9 ORX99429.1 - 5.5e-59 198.7 0.1 1.1e-58 197.8 0.1 1.5 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.9 ORX99429.1 - 4.7e-58 195.5 0.1 1.2e-57 194.2 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.9 ORX99429.1 - 1.6e-29 102.7 0.2 1.4e-28 99.6 0.0 2.8 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain Rax2 PF12768.7 ORX99478.1 - 0.013 15.0 0.0 0.018 14.5 0.0 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity PAP_PilO PF06864.12 ORX99478.1 - 0.02 13.7 0.0 0.03 13.2 0.0 1.2 1 0 0 1 1 1 0 Pilin accessory protein (PilO) TMEM154 PF15102.6 ORX99478.1 - 0.099 12.6 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family Vpu PF00558.19 ORX99478.1 - 0.16 11.8 0.0 0.25 11.1 0.0 1.2 1 0 0 1 1 1 0 Vpu protein Glyco_hydro_53 PF07745.13 ORX99484.1 - 1.6e-106 356.1 0.8 1.9e-106 355.9 0.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 RRM_1 PF00076.22 ORX99485.1 - 6.8e-31 105.9 0.1 1.7e-06 27.8 0.1 5.4 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 ORX99485.1 - 6.1e-28 96.5 0.0 1.3e-22 79.4 0.0 3.7 4 0 0 4 4 4 2 Occluded RNA-recognition motif RRM_3 PF08777.11 ORX99485.1 - 0.064 13.3 0.0 0.064 13.3 0.0 4.4 5 0 0 5 5 5 0 RNA binding motif RRM_Rrp7 PF17799.1 ORX99485.1 - 0.065 13.0 3.9 0.22 11.3 0.0 3.1 3 1 1 4 4 4 0 Rrp7 RRM-like N-terminal domain TetR_C_2 PF08361.11 ORX99485.1 - 0.17 12.0 0.1 0.46 10.6 0.1 1.7 1 0 0 1 1 1 0 MAATS-type transcriptional repressor, C-terminal region Neur_chan_memb PF02932.16 ORX99485.1 - 3.4 7.7 4.7 1.5 8.8 0.3 2.4 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Ribosomal_L22 PF00237.19 ORX99486.1 - 1.1e-17 64.1 0.7 1.1e-14 54.5 0.7 2.9 1 1 0 1 1 1 1 Ribosomal protein L22p/L17e PA26 PF04636.13 ORX99486.1 - 2.4 7.0 4.9 0.68 8.8 1.2 1.7 1 1 1 2 2 2 0 PA26 p53-induced protein (sestrin) UTP15_C PF09384.10 ORX99487.1 - 1.5e-42 144.7 0.0 5.2e-42 143.0 0.0 1.9 2 0 0 2 2 2 1 UTP15 C terminal WD40 PF00400.32 ORX99487.1 - 5.6e-20 71.3 3.1 0.00015 22.4 0.1 6.4 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX99487.1 - 9e-08 32.3 0.8 0.13 12.6 0.1 4.9 2 1 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain RAB3GAP2_N PF14655.6 ORX99487.1 - 0.066 12.5 0.0 2.8 7.1 0.0 2.2 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Homeodomain PF00046.29 ORX99488.1 - 9.7e-10 38.2 0.3 3.4e-09 36.4 0.3 1.9 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 ORX99488.1 - 1.9e-08 34.0 0.6 6.1e-08 32.4 0.6 1.9 1 0 0 1 1 1 1 Homeobox KN domain Sdh5 PF03937.16 ORX99489.1 - 1.3e-23 82.7 0.4 2.4e-23 81.9 0.4 1.4 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase Homeodomain PF00046.29 ORX99490.1 - 1.8e-11 43.7 0.2 3.7e-11 42.7 0.2 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 ORX99490.1 - 3.8e-07 29.9 0.5 3.8e-07 29.9 0.5 2.6 2 0 0 2 2 2 1 Homeobox KN domain zf-C2H2_4 PF13894.6 ORX99490.1 - 0.036 14.9 2.2 0.036 14.9 2.2 6.8 6 0 0 6 6 6 0 C2H2-type zinc finger Homeodomain PF00046.29 ORX99491.1 - 1.2e-12 47.4 0.1 3.2e-12 46.1 0.1 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 ORX99491.1 - 2.2e-07 30.7 0.2 9e-07 28.7 0.1 2.1 2 0 0 2 2 2 1 Homeobox KN domain MlrC_C PF07171.12 ORX99491.1 - 0.23 11.6 0.0 0.56 10.4 0.0 1.6 2 0 0 2 2 2 0 MlrC C-terminus zf-C2H2 PF00096.26 ORX99491.1 - 0.51 10.9 26.6 1 9.9 4.0 5.8 5 0 0 5 5 5 0 Zinc finger, C2H2 type Homeodomain PF00046.29 ORX99492.1 - 1.1e-11 44.4 0.2 1.9e-11 43.6 0.2 1.3 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 ORX99492.1 - 4.1e-07 29.8 0.5 9.2e-07 28.7 0.5 1.5 1 0 0 1 1 1 1 Homeobox KN domain PLDc_2 PF13091.6 ORX99493.1 - 1.3e-23 83.4 0.0 8.6e-17 61.3 0.0 2.6 2 1 0 2 2 2 2 PLD-like domain PLDc PF00614.22 ORX99493.1 - 1.1e-06 28.5 0.1 0.0006 19.9 0.0 2.4 2 0 0 2 2 2 2 Phospholipase D Active site motif Regulator_TrmB PF11495.8 ORX99493.1 - 0.0072 15.5 0.3 0.75 8.9 0.0 2.4 2 0 0 2 2 2 2 Archaeal transcriptional regulator TrmB Tyr-DNA_phospho PF06087.12 ORX99493.1 - 0.069 12.0 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 Tyrosyl-DNA phosphodiesterase ECR1_N PF14382.6 ORX99494.1 - 8.4e-16 57.5 0.8 2.2e-15 56.1 0.8 1.8 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region KH_6 PF15985.5 ORX99494.1 - 7.7e-05 23.0 0.1 0.00014 22.1 0.1 1.4 1 0 0 1 1 1 1 KH domain Rrp40_N PF18311.1 ORX99494.1 - 0.038 13.9 0.3 0.096 12.6 0.3 1.6 1 0 0 1 1 1 0 Exosome complex exonuclease Rrp40 N-terminal domain EXOSC1 PF10447.9 ORX99494.1 - 0.065 13.8 0.4 1.3 9.6 0.0 2.7 3 0 0 3 3 3 0 Exosome component EXOSC1/CSL4 TMEM234 PF10639.9 ORX99496.1 - 1.2e-41 141.4 0.6 1.4e-41 141.1 0.6 1.0 1 0 0 1 1 1 1 Putative transmembrane family 234 EamA PF00892.20 ORX99496.1 - 3.3e-05 24.1 8.2 0.023 14.9 4.5 2.4 2 1 0 2 2 2 2 EamA-like transporter family DUF3431 PF11913.8 ORX99497.1 - 1e-84 283.7 0.0 1.3e-84 283.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) DUF4690 PF15756.5 ORX99498.1 - 0.018 15.6 4.6 0.052 14.1 4.6 1.7 1 0 0 1 1 1 0 Small Novel Rich in Cartilage Glycophorin_A PF01102.18 ORX99498.1 - 0.025 14.8 0.1 0.062 13.6 0.1 1.6 1 0 0 1 1 1 0 Glycophorin A SAYSvFN PF10260.9 ORX99498.1 - 0.18 11.7 0.6 0.36 10.8 0.6 1.4 1 0 0 1 1 1 0 Uncharacterized conserved domain (SAYSvFN) FSA_C PF10479.9 ORX99498.1 - 3.4 5.7 7.2 4.7 5.2 7.2 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus PhyH PF05721.13 ORX99499.1 - 4.1e-48 164.4 0.0 6.6e-48 163.7 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Ole-e-6 PF09253.10 ORX99500.1 - 0.86 9.6 6.2 2.9 7.9 6.2 1.8 1 0 0 1 1 1 0 Pollen allergen ole e 6 adh_short PF00106.25 ORX99502.1 - 1.6e-34 119.1 0.0 3.6e-34 117.9 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORX99502.1 - 9.2e-25 87.6 0.0 1.3e-24 87.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORX99502.1 - 6.6e-07 29.4 0.0 1.5e-06 28.2 0.0 1.6 1 1 0 1 1 1 1 KR domain NAD_binding_7 PF13241.6 ORX99502.1 - 0.002 18.5 0.0 0.077 13.4 0.0 2.3 2 0 0 2 2 2 1 Putative NAD(P)-binding Epimerase PF01370.21 ORX99502.1 - 0.0047 16.4 0.3 0.06 12.8 0.0 2.5 3 0 0 3 3 3 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ORX99502.1 - 0.049 13.0 0.0 0.15 11.4 0.0 1.7 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase CMD PF02627.20 ORX99503.1 - 0.064 13.3 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Carboxymuconolactone decarboxylase family Ost5 PF05251.12 ORX99504.1 - 0.0025 18.0 0.7 0.0081 16.4 0.7 1.8 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit 5 MFS_1 PF07690.16 ORX99504.1 - 0.055 12.4 7.7 0.059 12.3 7.7 1.0 1 0 0 1 1 1 0 Major Facilitator Superfamily Cu-oxidase PF00394.22 ORX99505.1 - 3.1e-32 111.9 0.0 2.7e-29 102.3 0.0 2.4 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 ORX99505.1 - 2.7e-26 91.9 1.1 4.8e-26 91.1 0.0 2.0 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 ORX99505.1 - 1.6e-18 66.7 9.2 2.4e-16 59.7 3.3 3.5 3 2 0 3 3 3 2 Multicopper oxidase EAP30 PF04157.16 ORX99537.1 - 5.7e-64 215.6 0.5 6.5e-64 215.5 0.5 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family AAR2 PF05282.11 ORX99538.1 - 5e-94 315.6 0.1 8.9e-94 314.8 0.1 1.3 1 0 0 1 1 1 1 AAR2 protein zf-LITAF-like PF10601.9 ORX99539.1 - 4.5e-23 81.3 5.1 6.2e-23 80.9 5.1 1.2 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain Zn-ribbon_8 PF09723.10 ORX99539.1 - 0.015 15.4 0.2 0.13 12.4 0.1 2.3 2 0 0 2 2 2 0 Zinc ribbon domain NCD3G PF07562.14 ORX99539.1 - 0.31 11.0 5.3 1 9.4 5.3 1.8 1 1 0 1 1 1 0 Nine Cysteines Domain of family 3 GPCR Lar_restr_allev PF14354.6 ORX99539.1 - 0.45 10.9 5.3 2.1 8.8 5.3 2.0 1 1 0 1 1 1 0 Restriction alleviation protein Lar Zn_Tnp_IS1595 PF12760.7 ORX99539.1 - 0.7 9.9 6.0 8.5 6.5 0.1 2.4 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zf-ISL3 PF14690.6 ORX99539.1 - 0.96 10.2 5.0 7.1 7.4 0.4 2.4 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 AAA PF00004.29 ORX99542.1 - 1.5e-60 203.4 0.1 2.5e-43 147.7 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 ORX99542.1 - 7e-17 61.0 0.0 1.9e-08 34.0 0.0 3.0 3 0 0 3 3 2 2 AAA+ lid domain AAA_16 PF13191.6 ORX99542.1 - 3.9e-13 50.2 0.1 0.0026 18.2 0.0 4.4 2 2 1 4 4 4 2 AAA ATPase domain AAA_5 PF07728.14 ORX99542.1 - 9.2e-12 45.1 0.0 3.9e-07 30.1 0.0 2.8 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 ORX99542.1 - 9.8e-08 32.4 0.2 0.0025 18.1 0.0 3.6 2 2 1 4 4 4 2 AAA domain AAA_14 PF13173.6 ORX99542.1 - 2.4e-07 30.9 0.0 0.0049 16.9 0.0 2.3 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 ORX99542.1 - 4e-07 30.1 0.3 0.038 13.9 0.0 3.5 2 2 1 3 3 3 2 NACHT domain Sigma54_activ_2 PF14532.6 ORX99542.1 - 2e-06 28.0 0.0 0.066 13.3 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain RNA_helicase PF00910.22 ORX99542.1 - 4.9e-06 26.9 0.0 0.056 13.8 0.0 2.5 2 0 0 2 2 2 2 RNA helicase AAA_2 PF07724.14 ORX99542.1 - 5e-06 26.7 0.0 0.0011 19.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) TniB PF05621.11 ORX99542.1 - 3.5e-05 23.3 0.0 0.51 9.7 0.0 3.8 3 1 0 4 4 4 1 Bacterial TniB protein Bac_DnaA PF00308.18 ORX99542.1 - 3.8e-05 23.6 0.0 0.0019 18.1 0.0 2.4 2 0 0 2 2 2 1 Bacterial dnaA protein Mg_chelatase PF01078.21 ORX99542.1 - 7.2e-05 22.3 0.1 0.36 10.2 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 ORX99542.1 - 9e-05 22.1 0.0 0.25 10.8 0.0 2.6 2 1 0 2 2 2 2 P-loop containing dynein motor region Vps4_C PF09336.10 ORX99542.1 - 0.00013 21.9 0.2 0.11 12.5 0.0 3.2 3 0 0 3 3 3 1 Vps4 C terminal oligomerisation domain AAA_33 PF13671.6 ORX99542.1 - 0.00027 21.1 0.0 0.065 13.4 0.0 2.6 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.12 ORX99542.1 - 0.00029 20.6 0.0 0.0054 16.5 0.0 2.6 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 ORX99542.1 - 0.00041 20.6 0.0 0.03 14.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 ORX99542.1 - 0.00045 19.5 0.0 0.005 16.1 0.0 2.3 2 0 0 2 2 2 1 TIP49 P-loop domain ATPase PF06745.13 ORX99542.1 - 0.0006 19.2 0.1 0.047 13.0 0.0 2.9 3 1 0 3 3 3 1 KaiC AAA_25 PF13481.6 ORX99542.1 - 0.00078 19.1 0.4 4.4 6.8 0.0 3.6 2 2 2 4 4 4 1 AAA domain ATPase_2 PF01637.18 ORX99542.1 - 0.001 19.0 0.0 1.3 8.9 0.0 3.1 2 1 0 2 2 2 1 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 ORX99542.1 - 0.0012 18.6 0.0 1.3 8.7 0.0 2.8 2 1 0 2 2 2 1 Sigma-54 interaction domain Zeta_toxin PF06414.12 ORX99542.1 - 0.0014 18.0 0.0 1.1 8.5 0.0 3.1 3 0 0 3 3 3 1 Zeta toxin DUF815 PF05673.13 ORX99542.1 - 0.0024 17.1 0.0 1.3 8.2 0.0 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 ORX99542.1 - 0.0034 17.1 0.0 1.2 8.8 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein CDC48_N PF02359.18 ORX99542.1 - 0.0043 17.2 0.0 0.016 15.4 0.0 1.9 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain Rad17 PF03215.15 ORX99542.1 - 0.0057 16.6 0.0 1.6 8.7 0.0 2.6 2 1 0 2 2 2 1 Rad17 P-loop domain AAA_18 PF13238.6 ORX99542.1 - 0.014 16.0 0.0 0.89 10.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.25 ORX99542.1 - 0.017 14.8 0.0 0.42 10.2 0.0 2.6 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain ABC_tran PF00005.27 ORX99542.1 - 0.026 15.0 0.0 0.57 10.7 0.0 2.4 2 0 0 2 2 2 0 ABC transporter SRPRB PF09439.10 ORX99542.1 - 0.059 12.8 0.1 7.8 5.9 0.0 3.1 2 1 0 3 3 3 0 Signal recognition particle receptor beta subunit AAA_24 PF13479.6 ORX99542.1 - 0.063 13.0 0.0 0.75 9.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 ORX99542.1 - 0.077 12.7 0.0 0.99 9.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain Molydop_binding PF01568.21 ORX99542.1 - 0.098 12.7 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Molydopterin dinucleotide binding domain AAA_3 PF07726.11 ORX99542.1 - 0.14 12.0 0.0 1.7 8.5 0.0 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 ORX99542.1 - 0.17 11.8 0.0 51 3.7 0.0 3.4 3 1 0 3 3 3 0 NTPase DAP3 PF10236.9 ORX99542.1 - 0.19 10.9 0.0 3.3 6.8 0.0 2.3 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 AAA_23 PF13476.6 ORX99542.1 - 0.35 11.3 0.8 1.1 9.7 0.0 2.1 2 1 1 3 3 1 0 AAA domain Phage_lysis PF03245.13 ORX99543.1 - 0.015 15.4 0.4 0.015 15.4 0.4 2.6 2 0 0 2 2 2 0 Bacteriophage Rz lysis protein Death PF00531.22 ORX99543.1 - 0.045 13.9 0.0 0.18 12.0 0.0 2.0 2 0 0 2 2 2 0 Death domain Abhydrolase_3 PF07859.13 ORX99544.1 - 8.8e-44 149.9 0.0 3.9e-29 102.0 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold COesterase PF00135.28 ORX99544.1 - 3.1e-05 23.0 0.0 6e-05 22.1 0.0 1.4 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 ORX99544.1 - 0.039 13.4 0.0 0.84 9.1 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family Foie-gras_1 PF11817.8 ORX99545.1 - 0.037 13.6 0.0 0.038 13.6 0.0 1.1 1 0 0 1 1 1 0 Foie gras liver health family 1 DNA_binding_1 PF01035.20 ORX99546.1 - 5.9e-24 84.0 0.1 7.9e-24 83.6 0.1 1.1 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Bud13 PF09736.9 ORX99547.1 - 1.9e-46 158.0 3.7 1.9e-46 158.0 3.7 2.7 2 1 1 3 3 3 1 Pre-mRNA-splicing factor of RES complex Ribosomal_L50 PF10501.9 ORX99548.1 - 3.8e-12 46.3 0.0 8.9e-12 45.1 0.0 1.6 1 0 0 1 1 1 1 Ribosomal subunit 39S Actin PF00022.19 ORX99549.1 - 1.6e-85 287.2 0.0 1.6e-84 283.9 0.0 1.9 1 1 0 1 1 1 1 Actin CorA PF01544.18 ORX99550.1 - 0.0017 17.7 2.5 0.0041 16.5 2.5 1.6 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF1289 PF06945.13 ORX99550.1 - 0.082 12.7 0.3 0.22 11.3 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1289) Pkinase PF00069.25 ORX99551.1 - 5.8e-21 75.0 0.0 8.6e-21 74.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX99551.1 - 4.2e-11 42.6 0.0 1.2e-10 41.2 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase HRI1 PF16815.5 ORX99552.1 - 9.4e-58 195.6 0.1 1.1e-57 195.5 0.1 1.0 1 0 0 1 1 1 1 Protein HRI1 DUF4453 PF14627.6 ORX99552.1 - 0.0036 17.4 0.0 0.11 12.7 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4453) Ribosomal_L13e PF01294.18 ORX99553.1 - 3.9e-74 248.4 3.1 5.6e-74 247.9 3.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L13e HrcA_DNA-bdg PF03444.15 ORX99553.1 - 0.018 14.7 0.0 0.028 14.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding KIAA1430 PF13879.6 ORX99554.1 - 0.17 12.6 8.8 0.8 10.5 8.8 2.2 1 0 0 1 1 1 0 KIAA1430 homologue Cep57_CLD_2 PF14197.6 ORX99554.1 - 0.61 10.2 11.4 0.072 13.2 6.0 2.3 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 DUF4200 PF13863.6 ORX99554.1 - 1.1 9.7 9.5 6.1 7.3 9.5 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) LRR_8 PF13855.6 ORX99555.1 - 2.3e-30 104.1 46.6 3.3e-07 30.0 0.4 9.4 4 3 8 12 12 12 11 Leucine rich repeat LRR_4 PF12799.7 ORX99555.1 - 8.1e-25 86.5 50.4 0.00016 21.9 0.2 11.2 5 3 10 15 15 15 11 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 ORX99555.1 - 3.4e-06 26.7 21.8 0.015 14.8 0.4 5.7 2 2 2 5 5 5 4 Leucine-rich repeat LRR_6 PF13516.6 ORX99555.1 - 0.0012 18.7 28.7 0.84 9.9 0.3 9.3 11 0 0 11 11 11 3 Leucine Rich repeat LRR_1 PF00560.33 ORX99555.1 - 0.011 16.2 26.2 4.7 8.1 0.1 10.2 11 0 0 11 11 11 0 Leucine Rich Repeat Aldo_ket_red PF00248.21 ORX99556.1 - 1.7e-66 224.4 0.0 2e-66 224.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family MFS_1 PF07690.16 ORX99557.1 - 3.8e-26 91.8 33.1 5.6e-26 91.3 33.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily COX14 PF14880.6 ORX99557.1 - 0.04 13.8 0.1 0.13 12.1 0.1 1.8 1 0 0 1 1 1 0 Cytochrome oxidase c assembly DUF2244 PF10003.9 ORX99557.1 - 0.58 9.8 0.0 0.58 9.8 0.0 3.0 3 0 0 3 3 3 0 Integral membrane protein (DUF2244) Pectate_lyase_3 PF12708.7 ORX99558.1 - 2e-91 305.6 14.3 3.1e-77 259.3 2.3 3.2 3 0 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 ORX99558.1 - 1.9e-07 30.7 3.2 0.0016 18.1 0.1 2.6 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase 4HBT PF03061.22 ORX99559.1 - 3.8e-08 33.6 0.0 1.3e-07 31.9 0.0 1.8 2 0 0 2 2 2 1 Thioesterase superfamily Inositol_P PF00459.25 ORX99560.1 - 1.5e-66 224.7 0.0 1.7e-66 224.5 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Pribosyltran PF00156.27 ORX99561.1 - 1e-06 28.4 0.0 1.8e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain DPM3 PF08285.11 ORX99561.1 - 0.19 11.9 0.2 0.39 10.9 0.2 1.5 1 0 0 1 1 1 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) F-box-like PF12937.7 ORX99562.1 - 8.7e-06 25.5 0.0 2.4e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORX99562.1 - 0.12 12.3 2.0 0.2 11.5 0.0 2.5 3 0 0 3 3 3 0 F-box domain HSF_DNA-bind PF00447.17 ORX99563.1 - 1.1e-29 102.9 0.9 1.8e-29 102.2 0.9 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding BTB PF00651.31 ORX99564.1 - 3.7e-07 30.4 0.0 1.3e-06 28.6 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain Skp1_POZ PF03931.15 ORX99564.1 - 0.0071 16.5 0.0 0.019 15.1 0.0 1.7 1 1 1 2 2 2 1 Skp1 family, tetramerisation domain UQ_con PF00179.26 ORX99565.1 - 2.1e-43 147.3 0.1 2.4e-43 147.1 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 ORX99565.1 - 3.3e-05 23.6 0.0 4.1e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 ORX99565.1 - 0.00017 21.8 0.0 0.0002 21.6 0.0 1.3 1 1 0 1 1 1 1 RWD domain UEV PF05743.13 ORX99565.1 - 0.054 13.3 0.0 0.07 13.0 0.0 1.2 1 0 0 1 1 1 0 UEV domain Ysc84 PF04366.12 ORX99605.1 - 2.4e-39 134.0 0.3 4.1e-39 133.3 0.3 1.4 1 0 0 1 1 1 1 Las17-binding protein actin regulator SH3_1 PF00018.28 ORX99605.1 - 8.1e-14 51.0 0.6 2.8e-13 49.3 0.2 2.0 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 ORX99605.1 - 1.1e-11 44.2 0.2 2.9e-11 42.9 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.6 ORX99605.1 - 4.9e-10 39.1 0.0 9.5e-10 38.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain TGF_beta_GS PF08515.12 ORX99605.1 - 4.7 6.8 5.5 2.6 7.6 2.9 2.0 2 0 0 2 2 2 0 Transforming growth factor beta type I GS-motif Asparaginase_2 PF01112.18 ORX99606.1 - 2e-56 191.3 0.0 3.6e-49 167.5 0.0 2.4 2 0 0 2 2 2 2 Asparaginase Acetyltransf_7 PF13508.7 ORX99606.1 - 0.15 12.5 0.0 0.29 11.6 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Asp PF00026.23 ORX99608.1 - 1.5e-11 44.3 0.0 2e-11 43.9 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease VSP PF03302.13 ORX99608.1 - 0.00057 18.8 0.1 0.00088 18.2 0.1 1.1 1 0 0 1 1 1 1 Giardia variant-specific surface protein DUF4448 PF14610.6 ORX99609.1 - 0.11 12.2 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) CcmD PF04995.14 ORX99609.1 - 5.4 7.2 9.2 5.7 7.1 0.3 3.3 3 0 0 3 3 3 0 Heme exporter protein D (CcmD) HET PF06985.11 ORX99610.1 - 1.8e-27 96.4 0.1 3.4e-27 95.6 0.1 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Phage_holin_3_6 PF07332.11 ORX99610.1 - 0.13 12.3 5.3 0.33 11.0 5.3 1.6 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DUF2207 PF09972.9 ORX99610.1 - 8.1 5.1 10.6 14 4.3 10.6 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) HET PF06985.11 ORX99611.1 - 3.2e-11 43.8 8.5 1.7e-09 38.2 0.8 2.2 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Fungal_trans PF04082.18 ORX99612.1 - 1e-15 57.5 0.3 1.3e-14 53.9 0.0 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORX99612.1 - 1.8e-07 31.1 9.7 3.7e-07 30.2 9.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dioxygenase_C PF00775.21 ORX99613.1 - 2.7e-37 128.0 0.0 3.6e-37 127.6 0.0 1.1 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 ORX99613.1 - 5.6e-25 87.0 0.1 8.6e-25 86.4 0.1 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 ORX99613.1 - 0.012 15.9 0.0 0.043 14.1 0.0 1.8 1 1 0 1 1 1 0 Carboxypeptidase regulatory-like domain DUF3295 PF11702.8 ORX99617.1 - 8.9e-138 460.7 49.8 2e-137 459.5 49.8 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3295) DUF1752 PF08550.10 ORX99617.1 - 8e-09 35.2 1.4 1.6e-08 34.2 1.4 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) FdhE PF04216.12 ORX99619.1 - 0.058 13.3 0.3 0.11 12.3 0.3 1.4 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation His_Me_b4a2 PF18275.1 ORX99619.1 - 0.3 11.2 4.4 0.61 10.2 4.4 1.5 1 0 0 1 1 1 0 His-Me finger endonuclease beta4-alpha2 domain Cpn60_TCP1 PF00118.24 ORX99622.1 - 4.7e-149 497.2 3.5 5.8e-149 496.9 3.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Enolase_N PF03952.16 ORX99622.1 - 0.11 12.6 2.2 3.8 7.7 0.1 3.2 3 0 0 3 3 3 0 Enolase, N-terminal domain Chromo_shadow PF01393.19 ORX99623.1 - 4.5e-16 58.7 0.3 9.8e-16 57.6 0.1 1.7 2 0 0 2 2 2 1 Chromo shadow domain Chromo PF00385.24 ORX99623.1 - 9.1e-12 44.7 1.3 9.1e-12 44.7 1.3 2.0 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain HET PF06985.11 ORX99625.1 - 3.3e-18 66.5 0.1 3.6e-18 66.3 0.1 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.16 ORX99628.1 - 4.7e-25 88.3 37.0 4.7e-22 78.4 10.3 2.3 1 1 0 2 2 2 2 Major Facilitator Superfamily Per1 PF04080.13 ORX99673.1 - 2e-22 80.2 1.6 2.1e-22 80.1 1.6 1.0 1 0 0 1 1 1 1 Per1-like family PAP2 PF01569.21 ORX99674.1 - 7.8e-26 90.5 3.0 7.8e-26 90.5 3.0 2.0 3 0 0 3 3 3 1 PAP2 superfamily PAP2_C PF14360.6 ORX99674.1 - 1.6 9.3 6.7 0.18 12.3 1.4 2.2 2 1 0 2 2 2 0 PAP2 superfamily C-terminal TPPK_C PF12555.8 ORX99674.1 - 3.5 7.7 6.4 2.5 8.2 3.2 2.3 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal TNFR_16_TM PF18422.1 ORX99674.1 - 3.7 7.6 5.6 15 5.6 0.4 2.6 2 0 0 2 2 2 0 Tumor necrosis factor receptor member 16 trans-membrane domain DUF983 PF06170.12 ORX99674.1 - 5.8 7.4 6.5 31 5.0 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF983) CDC45 PF02724.14 ORX99675.1 - 0.0027 16.1 8.9 0.0035 15.7 8.9 1.1 1 0 0 1 1 1 1 CDC45-like protein DUF3516 PF12029.8 ORX99675.1 - 0.022 13.9 0.5 0.022 13.9 0.5 2.4 2 2 0 2 2 2 0 Domain of unknown function (DUF3516) CobT PF06213.12 ORX99675.1 - 0.023 14.1 19.3 0.035 13.5 19.3 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Roughex PF06020.11 ORX99675.1 - 0.19 10.8 6.5 0.28 10.2 6.5 1.2 1 0 0 1 1 1 0 Drosophila roughex protein DUF2722 PF10846.8 ORX99675.1 - 1.1 8.1 6.9 1.9 7.4 6.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) SDA1 PF05285.12 ORX99675.1 - 3.4 7.0 26.2 6 6.2 26.2 1.3 1 0 0 1 1 1 0 SDA1 TPX2 PF06886.11 ORX99675.1 - 8.1 6.8 10.9 20 5.5 10.9 1.7 1 0 0 1 1 1 0 Targeting protein for Xklp2 (TPX2) eIF-3c_N PF05470.12 ORX99676.1 - 1.5e-169 565.2 18.5 8e-139 463.7 1.0 2.6 3 0 0 3 3 3 2 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 ORX99676.1 - 7.6e-14 52.1 2.3 1.7e-13 51.0 0.1 2.7 3 0 0 3 3 3 1 PCI domain Sigma70_ner PF04546.13 ORX99676.1 - 0.33 10.8 11.5 1.3 8.8 11.5 2.0 1 0 0 1 1 1 0 Sigma-70, non-essential region Nop14 PF04147.12 ORX99676.1 - 1.1 7.4 13.5 1.7 6.8 13.5 1.2 1 0 0 1 1 1 0 Nop14-like family Pkinase PF00069.25 ORX99677.1 - 4.8e-50 170.4 0.0 8.6e-50 169.5 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX99677.1 - 1.7e-23 83.3 0.0 3.2e-23 82.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 ORX99677.1 - 0.0021 18.0 1.4 0.005 16.8 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 ORX99677.1 - 0.0085 15.7 1.8 0.011 15.3 0.2 1.9 2 1 0 2 2 2 1 RIO1 family K_oxygenase PF13434.6 ORX99678.1 - 4.5e-103 345.0 0.0 5.8e-103 344.6 0.0 1.1 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 ORX99678.1 - 4e-06 26.3 0.0 0.0001 21.6 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ORX99678.1 - 5.6e-06 25.8 0.1 0.00028 20.3 0.0 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Cyclase PF04199.13 ORX99678.1 - 0.019 15.2 0.0 0.038 14.2 0.0 1.4 1 0 0 1 1 1 0 Putative cyclase AMP-binding PF00501.28 ORX99680.1 - 1e-302 1002.8 0.0 5e-81 272.5 0.0 4.3 4 0 0 4 4 4 4 AMP-binding enzyme Condensation PF00668.20 ORX99680.1 - 2.4e-210 699.0 0.0 1.3e-42 146.0 0.0 6.4 6 0 0 6 6 6 6 Condensation domain PP-binding PF00550.25 ORX99680.1 - 1.8e-49 166.0 13.9 8.2e-10 38.9 0.0 7.1 6 0 0 6 6 6 6 Phosphopantetheine attachment site AMP-binding_C PF13193.6 ORX99680.1 - 5e-16 59.4 0.5 0.0056 17.6 0.0 5.0 4 0 0 4 4 4 3 AMP-binding enzyme C-terminal domain WES_acyltransf PF03007.16 ORX99680.1 - 3.6e-05 23.7 0.0 5.7 6.6 0.0 4.5 4 0 0 4 4 4 2 Wax ester synthase-like Acyl-CoA acyltransferase domain Aldo_ket_red PF00248.21 ORX99680.1 - 0.18 11.0 0.0 1.8 7.7 0.0 2.5 3 0 0 3 3 3 0 Aldo/keto reductase family PE PF00934.20 ORX99680.1 - 0.38 11.1 1.9 1.4 9.3 0.2 2.6 2 0 0 2 2 2 0 PE family TFR_dimer PF04253.15 ORX99681.1 - 6.4e-32 110.2 0.0 1.1e-31 109.4 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 ORX99681.1 - 4.5e-17 62.4 0.0 7.7e-17 61.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 ORX99681.1 - 1e-12 47.9 0.0 2.4e-12 46.7 0.0 1.6 1 0 0 1 1 1 1 PA domain adh_short_C2 PF13561.6 ORX99682.1 - 8e-48 163.0 4.7 1.7e-44 152.1 4.7 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORX99682.1 - 6.8e-43 146.4 3.6 8.4e-43 146.1 3.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORX99682.1 - 1.9e-14 53.9 0.3 3e-14 53.3 0.3 1.3 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 ORX99682.1 - 0.0024 17.8 0.7 0.004 17.1 0.7 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 ORX99682.1 - 0.0075 16.3 0.4 0.014 15.5 0.4 1.5 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Shikimate_DH PF01488.20 ORX99682.1 - 0.11 12.6 0.1 0.22 11.6 0.1 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase RRM_1 PF00076.22 ORX99683.1 - 7.8e-23 80.1 0.0 6.4e-11 41.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 ORX99683.1 - 0.049 13.5 0.0 0.47 10.3 0.0 2.0 2 0 0 2 2 2 0 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 ORX99683.1 - 0.17 11.9 0.0 1.5 8.9 0.0 2.1 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif ETF_QO PF05187.13 ORX99684.1 - 1.8e-48 163.0 0.3 3e-48 162.3 0.3 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S DAO PF01266.24 ORX99684.1 - 3.1e-08 33.6 0.2 0.00037 20.2 0.2 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 ORX99684.1 - 5.3e-07 29.1 0.6 0.0055 15.8 0.3 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 ORX99684.1 - 1.4e-06 28.4 0.0 4.9e-06 26.7 0.0 2.0 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 ORX99684.1 - 6.4e-06 25.6 0.0 0.0025 17.1 0.0 2.2 2 0 0 2 2 2 2 Thi4 family Pyr_redox_2 PF07992.14 ORX99684.1 - 3.5e-05 23.2 0.0 6.7e-05 22.3 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ORX99684.1 - 0.00048 18.9 0.1 0.00074 18.3 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.19 ORX99684.1 - 0.00053 19.3 0.1 0.0011 18.3 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 ORX99684.1 - 0.001 18.5 0.0 0.0016 17.8 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 ORX99684.1 - 0.0023 17.9 0.2 0.0063 16.5 0.2 1.9 1 1 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 ORX99684.1 - 0.0072 16.9 0.1 5.4 7.6 0.1 2.7 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ORX99684.1 - 0.0095 15.2 0.1 0.014 14.7 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_7 PF12838.7 ORX99684.1 - 0.032 14.8 0.8 0.085 13.5 0.8 1.7 1 0 0 1 1 1 0 4Fe-4S dicluster domain Trp_halogenase PF04820.14 ORX99684.1 - 0.046 12.6 0.0 0.27 10.1 0.0 1.9 1 1 1 2 2 2 0 Tryptophan halogenase Lycopene_cycl PF05834.12 ORX99684.1 - 0.052 12.6 0.2 0.086 11.9 0.2 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Amino_oxidase PF01593.24 ORX99684.1 - 0.084 12.1 0.0 0.18 11.1 0.0 1.5 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.21 ORX99684.1 - 0.12 11.7 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 ORX99684.1 - 0.13 11.3 0.0 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Utp14 PF04615.13 ORX99685.1 - 0.46 9.0 29.3 0.58 8.7 29.3 1.2 1 0 0 1 1 1 0 Utp14 protein Seipin PF06775.14 ORX99689.1 - 9.2e-50 169.5 0.0 1.3e-49 169.0 0.0 1.2 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) Oleosin PF01277.17 ORX99689.1 - 0.14 11.9 0.7 0.37 10.6 0.7 1.6 1 0 0 1 1 1 0 Oleosin Pex24p PF06398.11 ORX99689.1 - 0.15 11.0 0.4 0.32 9.9 0.4 1.5 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin PAN_4 PF14295.6 ORX99690.1 - 0.00012 21.9 3.0 0.0003 20.6 3.0 1.7 1 1 0 1 1 1 1 PAN domain PAN_1 PF00024.26 ORX99690.1 - 0.0004 20.3 0.1 0.00079 19.3 0.1 1.4 1 0 0 1 1 1 1 PAN domain DUF1412 PF07203.11 ORX99690.1 - 0.093 12.9 0.0 0.24 11.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1412) FRB_dom PF08771.11 ORX99692.1 - 0.12 12.8 0.0 0.45 11.0 0.0 1.9 1 0 0 1 1 1 0 FKBP12-rapamycin binding domain zf-PARP PF00645.18 ORX99693.1 - 3.1e-25 88.9 1.1 1e-24 87.2 1.1 2.0 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region CHZ PF09649.10 ORX99694.1 - 0.0013 18.2 0.3 0.0013 18.2 0.3 1.7 2 0 0 2 2 2 1 Histone chaperone domain CHZ p450 PF00067.22 ORX99697.1 - 5.9e-42 144.0 0.0 8.1e-42 143.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Abhydrolase_3 PF07859.13 ORX99698.1 - 4e-41 141.2 0.0 8e-41 140.2 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 ORX99698.1 - 0.039 12.8 0.2 0.28 10.0 0.2 2.0 1 1 0 1 1 1 0 Steryl acetyl hydrolase WD40 PF00400.32 ORX99754.1 - 3.2e-108 350.6 14.4 1.4e-10 41.6 0.0 10.7 11 0 0 11 11 11 10 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX99754.1 - 3.5e-36 123.4 0.0 0.0012 19.1 0.0 9.8 1 1 8 9 9 9 9 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 ORX99754.1 - 2.6e-14 53.0 2.2 4.7 6.1 0.0 9.5 1 1 7 10 10 10 5 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 ORX99754.1 - 8.2e-12 44.2 0.0 5.1 5.3 0.0 8.7 8 1 1 9 9 9 2 WD repeat-containing and planar cell polarity effector protein Fritz DUF1652 PF07865.11 ORX99754.1 - 9.9e-12 44.5 2.2 3.6 7.5 0.0 9.6 10 0 0 10 10 10 2 Protein of unknown function (DUF1652) PALB2_WD40 PF16756.5 ORX99754.1 - 2.6e-11 43.1 6.0 2.2 7.1 0.0 9.4 1 1 9 10 10 10 1 Partner and localizer of BRCA2 WD40 domain Nup160 PF11715.8 ORX99754.1 - 8.5e-11 41.2 9.4 4 5.9 0.0 9.4 1 1 8 10 10 10 3 Nucleoporin Nup120/160 Crust_neuro_H PF03858.13 ORX99754.1 - 2.3e-07 31.5 0.8 1.8e+02 3.0 0.0 8.6 9 0 0 9 9 9 0 Crustacean neurohormone H SecA_PP_bind PF01043.20 ORX99754.1 - 1.2e-05 25.9 0.4 1.7e+02 2.9 0.0 8.3 7 3 3 10 10 10 0 SecA preprotein cross-linking domain DUF3313 PF11769.8 ORX99754.1 - 1.3e-05 25.1 4.3 18 5.1 0.0 7.5 7 2 1 9 9 9 0 Protein of unknown function (DUF3313) 5-FTHF_cyc-lig PF01812.20 ORX99754.1 - 0.0014 18.5 7.2 19 5.0 0.1 6.3 4 2 0 7 7 7 0 5-formyltetrahydrofolate cyclo-ligase family OpuAC PF04069.12 ORX99754.1 - 0.0038 16.8 2.5 11 5.4 0.0 5.1 2 1 2 4 4 4 0 Substrate binding domain of ABC-type glycine betaine transport system WXG100 PF06013.12 ORX99754.1 - 0.03 14.5 0.0 1.2e+02 3.0 0.0 5.7 9 0 0 9 9 9 0 Proteins of 100 residues with WXG IKI3 PF04762.12 ORX99754.1 - 0.041 11.9 0.0 11 3.8 0.0 3.7 2 1 1 5 5 5 0 IKI3 family DUF3467 PF11950.8 ORX99754.1 - 0.085 13.1 0.0 4e+02 1.3 0.0 5.1 5 3 1 6 6 6 0 Protein of unknown function (DUF3467) WD40_like PF17005.5 ORX99754.1 - 0.14 11.4 0.0 1.1e+02 1.9 0.0 4.3 3 2 4 7 7 7 0 WD40-like domain DUF3261 PF11659.8 ORX99754.1 - 0.33 10.8 7.0 27 4.6 0.0 5.6 1 1 7 8 8 8 0 Protein of unknown function (DUF3261) CT_C_D PF02682.16 ORX99794.1 - 0.16 11.7 0.6 0.56 9.9 0.1 2.0 2 0 0 2 2 2 0 Carboxyltransferase domain, subdomain C and D Sugar_tr PF00083.24 ORX99796.1 - 2.7e-90 303.4 26.6 3.1e-90 303.2 26.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORX99796.1 - 1.5e-27 96.5 62.2 4.5e-25 88.3 35.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1996 PF09362.10 ORX99798.1 - 1e-81 274.4 6.7 1.2e-81 274.2 3.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1996) DUF1996 PF09362.10 ORX99799.1 - 2.7e-79 266.5 1.9 3.3e-79 266.2 1.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Coprogen_oxidas PF01218.18 ORX99800.1 - 7.5e-146 484.5 0.1 8.6e-146 484.3 0.1 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase Atg8 PF02991.16 ORX99801.1 - 2.4e-51 172.3 0.3 2.8e-51 172.0 0.3 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 ORX99801.1 - 3.2e-06 27.5 0.0 3.7e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 NCE101 PF11654.8 ORX99802.1 - 2.3e-10 40.0 0.0 2.7e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 Non-classical export protein 1 zf-CCCH PF00642.24 ORX99803.1 - 0.0022 17.9 3.8 0.0022 17.9 3.8 3.2 3 1 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3H1 PF10650.9 ORX99803.1 - 2.8 7.7 11.9 1.1 9.1 2.7 2.7 2 0 0 2 2 2 0 Putative zinc-finger domain NUDE_C PF04880.13 ORX99803.1 - 8.4 6.8 7.5 14 6.1 7.5 1.4 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region GST_C_3 PF14497.6 ORX99804.1 - 2.6e-28 98.1 0.6 6.6e-28 96.8 0.3 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 ORX99804.1 - 4.1e-05 23.7 0.1 8.3e-05 22.7 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 ORX99804.1 - 0.00079 19.4 0.0 0.0018 18.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Ribosomal_S7e PF01251.18 ORX99805.1 - 7e-82 273.6 0.1 8.2e-82 273.4 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e MIP PF00230.20 ORX99806.1 - 2.3e-29 102.7 5.3 2.8e-29 102.5 5.3 1.1 1 0 0 1 1 1 1 Major intrinsic protein Acetyltransf_1 PF00583.25 ORX99807.1 - 0.0033 17.6 0.0 0.0043 17.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ORX99807.1 - 0.035 14.0 0.0 0.67 9.9 0.0 2.0 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain PGG PF13962.6 ORX99808.1 - 0.47 10.3 4.7 0.14 12.0 1.2 1.9 2 0 0 2 2 2 0 Domain of unknown function Ank_5 PF13857.6 ORX99809.1 - 1.8e-05 24.9 0.2 0.12 12.7 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 ORX99809.1 - 0.0042 17.6 0.1 0.018 15.6 0.0 1.9 1 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 ORX99809.1 - 0.011 16.2 2.1 1.8 9.2 0.1 3.2 3 1 1 4 4 4 0 Ankyrin repeat Ank_4 PF13637.6 ORX99809.1 - 0.099 13.3 0.5 0.26 11.9 0.0 2.0 2 1 0 2 2 2 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 ORX99810.1 - 6.2e-17 62.0 0.2 9.9e-12 45.3 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORX99810.1 - 2.5e-14 53.4 0.0 1.3e-07 32.0 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORX99810.1 - 2.4e-13 48.9 0.1 0.00013 22.1 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 ORX99810.1 - 2.2e-12 47.0 0.0 0.0011 19.2 0.0 2.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 ORX99810.1 - 4.1e-12 46.0 0.5 9.1e-06 25.9 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat GHMP_kinases_C PF08544.13 ORX99810.1 - 0.024 15.0 0.4 0.047 14.1 0.2 1.6 1 1 1 2 2 2 0 GHMP kinases C terminal DHquinase_II PF01220.19 ORX99810.1 - 0.062 13.0 0.1 0.077 12.7 0.1 1.1 1 0 0 1 1 1 0 Dehydroquinase class II HD PF01966.22 ORX99812.1 - 1.9e-07 31.4 0.7 2.9e-07 30.8 0.7 1.3 1 0 0 1 1 1 1 HD domain Pex16 PF08610.10 ORX99813.1 - 3.2e-143 476.7 0.1 3.7e-143 476.6 0.1 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) MitMem_reg PF13012.6 ORX99814.1 - 5.9e-38 129.7 0.0 1.1e-37 128.8 0.0 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 ORX99814.1 - 4.8e-31 107.2 0.1 1.5e-30 105.6 0.0 1.8 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease tRNA_bind_2 PF13725.6 ORX99814.1 - 0.018 14.8 2.7 0.027 14.2 2.7 1.2 1 0 0 1 1 1 0 Possible tRNA binding domain SWIM PF04434.17 ORX99815.1 - 0.0024 17.5 4.8 0.0026 17.4 0.1 2.3 2 0 0 2 2 2 1 SWIM zinc finger CXCL17 PF15211.6 ORX99816.1 - 0.061 14.1 0.2 0.14 13.0 0.2 1.6 1 0 0 1 1 1 0 VEGF co-regulated chemokine 1 SWIRM PF04433.17 ORX99817.1 - 1.9e-13 50.5 0.1 3.8e-13 49.6 0.1 1.5 1 0 0 1 1 1 1 SWIRM domain PAF-AH_p_II PF03403.13 ORX99818.1 - 1.5e-10 40.1 0.0 2e-07 29.9 0.0 2.2 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 ORX99818.1 - 1.3e-06 27.5 0.1 3.5e-06 26.1 0.1 1.6 1 1 0 1 1 1 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 ORX99818.1 - 3.2e-05 23.3 0.0 0.012 14.9 0.1 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ORX99818.1 - 4.8e-05 24.1 2.6 7.5e-05 23.4 2.6 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 ORX99818.1 - 0.0011 18.8 0.1 0.71 9.6 0.0 2.3 2 0 0 2 2 2 2 Alpha/beta hydrolase family Chlorophyllase PF07224.11 ORX99818.1 - 0.014 14.5 0.0 0.36 9.8 0.0 2.3 2 0 0 2 2 2 0 Chlorophyllase Lipase_3 PF01764.25 ORX99818.1 - 0.018 14.9 0.1 0.035 14.0 0.1 1.4 1 0 0 1 1 1 0 Lipase (class 3) AXE1 PF05448.12 ORX99818.1 - 0.045 12.4 0.0 0.069 11.8 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Abhydrolase_1 PF00561.20 ORX99818.1 - 0.051 13.2 0.2 0.87 9.2 0.2 2.5 1 1 0 1 1 1 0 alpha/beta hydrolase fold Esterase PF00756.20 ORX99818.1 - 0.11 12.2 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Peptidase_S9 PF00326.21 ORX99818.1 - 0.18 11.3 0.0 0.3 10.5 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family CDC50 PF03381.15 ORX99820.1 - 3.3e-99 331.9 0.0 4.2e-99 331.6 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Peptidase_M43 PF05572.13 ORX99821.1 - 3.3e-09 36.8 1.1 3.3e-09 36.8 1.1 2.7 2 2 0 2 2 2 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 ORX99821.1 - 6.9e-06 26.3 0.2 1.3e-05 25.5 0.2 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M10 PF00413.24 ORX99821.1 - 0.0028 17.5 0.2 0.0053 16.6 0.2 1.6 1 1 0 1 1 1 1 Matrixin Reprolysin_4 PF13583.6 ORX99821.1 - 0.0078 15.9 0.3 0.017 14.7 0.2 1.7 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 ORX99821.1 - 0.011 16.3 0.4 0.036 14.6 0.4 2.0 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Metallopep PF12044.8 ORX99821.1 - 0.037 12.7 2.3 0.054 12.1 2.3 1.2 1 0 0 1 1 1 0 Putative peptidase family DUF4953 PF16313.5 ORX99821.1 - 0.15 11.2 0.1 0.26 10.4 0.1 1.3 1 0 0 1 1 1 0 Met-zincin PGAP1 PF07819.13 ORX99822.1 - 0.0019 18.0 0.0 0.0025 17.6 0.0 1.3 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 ORX99822.1 - 0.02 15.5 0.0 0.02 15.5 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF676 PF05057.14 ORX99822.1 - 0.032 13.7 0.0 0.034 13.6 0.0 1.1 1 0 0 1 1 1 0 Putative serine esterase (DUF676) BC10 PF06726.12 ORX99823.1 - 2e-12 47.2 8.9 2.9e-12 46.6 8.9 1.2 1 0 0 1 1 1 1 Bladder cancer-related protein BC10 Adeno_PV PF03910.13 ORX99823.1 - 0.59 8.8 1.7 0.71 8.5 1.7 1.0 1 0 0 1 1 1 0 Adenovirus minor core protein PV Peptidase_M1 PF01433.20 ORX99824.1 - 4.4e-83 278.1 5.2 7.1e-83 277.5 5.2 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 ORX99824.1 - 1.2e-78 264.8 0.0 2.3e-78 263.9 0.0 1.5 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 ORX99824.1 - 6.3e-44 150.4 0.4 1.3e-42 146.1 0.1 2.5 2 1 0 2 2 2 1 Peptidase M1 N-terminal domain DUF45 PF01863.17 ORX99824.1 - 0.079 13.0 0.0 0.21 11.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function DUF45 UCH PF00443.29 ORX99825.1 - 8.2e-11 41.9 0.0 1.3e-10 41.2 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DNA_mis_repair PF01119.19 ORX99871.1 - 5.9e-12 45.3 0.0 1.3e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 ORX99871.1 - 3.3e-09 36.7 0.0 6.7e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 ORX99871.1 - 1.4e-06 28.8 0.0 2.8e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase EutC PF05985.11 ORX99871.1 - 0.12 11.7 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine ammonia-lyase light chain (EutC) Ada_Zn_binding PF02805.16 ORX99872.1 - 3.3e-28 97.5 5.7 5e-28 96.9 5.7 1.3 1 0 0 1 1 1 1 Metal binding domain of Ada HTH_AraC PF00165.23 ORX99872.1 - 3.3e-09 36.6 0.0 5.9e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_18 PF12833.7 ORX99872.1 - 4.3e-06 26.9 0.0 8.8e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain VHP PF02209.19 ORX99872.1 - 0.0014 18.6 0.3 0.0014 18.6 0.3 2.1 3 0 0 3 3 3 1 Villin headpiece domain ANTH PF07651.16 ORX99872.1 - 0.13 11.2 0.3 5.2 6.0 0.1 2.1 2 0 0 2 2 2 0 ANTH domain Ephrin PF00812.17 ORX99873.1 - 0.022 14.7 0.0 0.031 14.3 0.0 1.1 1 0 0 1 1 1 0 Ephrin Cu-oxidase_2 PF07731.14 ORX99874.1 - 5.6e-22 77.9 1.2 2.5e-19 69.4 0.1 2.7 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 ORX99874.1 - 6.2e-20 71.4 1.1 1.1e-19 70.5 0.1 2.0 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.22 ORX99874.1 - 0.00052 20.2 0.0 0.047 13.8 0.0 3.3 3 1 0 3 3 3 1 Multicopper oxidase AA_permease PF00324.21 ORX99876.1 - 1.1e-115 387.0 45.3 1.4e-115 386.7 45.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ORX99876.1 - 5.5e-23 81.5 50.8 1.3e-22 80.3 49.5 1.8 1 1 1 2 2 2 2 Amino acid permease Pet100 PF09803.9 ORX99876.1 - 0.053 14.0 0.0 0.14 12.7 0.0 1.7 1 0 0 1 1 1 0 Pet100 NCE101 PF11654.8 ORX99876.1 - 0.11 12.2 1.4 0.26 11.0 0.4 2.1 2 0 0 2 2 2 0 Non-classical export protein 1 Glyco_hydro_17 PF00332.18 ORX99877.1 - 0.00039 20.1 0.3 0.49 9.9 0.1 2.3 2 0 0 2 2 2 2 Glycosyl hydrolases family 17 Epimerase PF01370.21 ORX99878.1 - 8e-17 61.5 0.0 2.3e-16 60.0 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ORX99878.1 - 5.7e-06 26.0 0.0 1.1e-05 25.0 0.0 1.6 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 ORX99878.1 - 6.7e-05 22.0 0.0 0.0001 21.4 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 ORX99878.1 - 0.0058 16.5 0.1 0.033 14.1 0.1 2.1 1 1 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 ORX99878.1 - 0.022 13.9 0.1 0.15 11.1 0.0 1.9 2 0 0 2 2 2 0 RmlD substrate binding domain FAD_binding_3 PF01494.19 ORX99879.1 - 1.8e-19 70.2 0.0 5.4e-19 68.6 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain SE PF08491.10 ORX99879.1 - 0.0039 16.3 0.0 0.012 14.7 0.0 1.8 2 0 0 2 2 2 1 Squalene epoxidase DUF2235 PF09994.9 ORX99880.1 - 1.5e-84 283.8 0.0 2.2e-84 283.2 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Amino_oxidase PF01593.24 ORX99882.1 - 2.9e-38 132.3 0.1 8.2e-38 130.9 0.1 1.7 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 ORX99882.1 - 2e-06 27.9 0.0 4.6e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 ORX99882.1 - 0.041 13.1 0.1 0.08 12.2 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain Fae PF08714.11 ORX99882.1 - 0.12 12.3 0.2 0.23 11.4 0.2 1.3 1 0 0 1 1 1 0 Formaldehyde-activating enzyme (Fae) Glyco_hydro_18 PF00704.28 ORX99883.1 - 2.7e-54 185.0 0.1 3.1e-54 184.8 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 ORX99883.1 - 1.1e-10 41.7 34.7 1.2e-09 38.4 21.0 2.9 2 0 0 2 2 2 2 Chitin recognition protein Glyco_hydro_16 PF00722.21 ORX99884.1 - 2e-07 30.7 0.7 2.8e-07 30.2 0.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Chitin_bind_1 PF00187.19 ORX99885.1 - 7.7e-18 64.7 78.0 2.7e-07 30.9 18.9 4.4 3 1 1 4 4 4 3 Chitin recognition protein LysM PF01476.20 ORX99885.1 - 0.015 15.3 0.0 0.025 14.7 0.0 1.3 1 0 0 1 1 1 0 LysM domain PPR_2 PF13041.6 ORX99886.1 - 2.5e-06 27.6 0.1 1.6 9.0 0.0 5.0 4 1 1 5 5 5 3 PPR repeat family PPR PF01535.20 ORX99886.1 - 0.0057 16.8 0.5 62 4.2 0.0 5.4 6 0 0 6 6 6 0 PPR repeat TPR_14 PF13428.6 ORX99886.1 - 1.1 10.3 3.6 8.9 7.4 0.0 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF3606 PF12244.8 ORX99887.1 - 0.29 11.1 1.7 0.56 10.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3606) Pkinase PF00069.25 ORX99888.1 - 1.9e-54 184.8 0.0 2.8e-54 184.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX99888.1 - 4.6e-35 121.1 0.0 7.1e-35 120.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 ORX99888.1 - 0.00041 19.4 0.1 0.016 14.2 0.0 2.2 2 0 0 2 2 2 1 Haspin like kinase domain Pkinase_fungal PF17667.1 ORX99888.1 - 0.00053 18.9 0.0 0.0017 17.2 0.0 1.8 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 ORX99888.1 - 0.00098 19.1 0.0 0.13 12.1 0.0 3.2 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.6 ORX99888.1 - 0.0055 16.1 0.0 0.013 14.9 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 ORX99888.1 - 0.031 13.6 0.0 0.062 12.7 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RRN3 PF05327.11 ORX99889.1 - 3.6e-178 593.6 0.1 3.6e-178 593.6 0.1 2.0 2 0 0 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 RecO_C PF02565.15 ORX99889.1 - 0.0012 18.7 0.0 0.0027 17.5 0.0 1.6 2 0 0 2 2 2 1 Recombination protein O C terminal Pro_isomerase PF00160.21 ORX99890.1 - 1.8e-49 168.0 0.4 2e-49 167.9 0.4 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf-RING_2 PF13639.6 ORX99891.1 - 8.4e-13 48.4 6.8 1.3e-12 47.8 6.8 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 ORX99891.1 - 3e-09 36.4 0.7 5.5e-09 35.6 0.7 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 ORX99891.1 - 1.9e-08 34.0 6.5 3.1e-08 33.3 6.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORX99891.1 - 2.1e-08 33.9 4.2 3.3e-08 33.3 4.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORX99891.1 - 1.2e-06 28.4 4.1 1.9e-06 27.7 4.1 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 ORX99891.1 - 2e-06 28.0 10.0 1.4e-05 25.2 10.0 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 ORX99891.1 - 5e-05 23.2 1.0 5e-05 23.2 1.0 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 ORX99891.1 - 0.00035 20.4 2.8 0.00073 19.3 2.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 ORX99891.1 - 0.0013 18.7 2.8 0.0035 17.4 2.8 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 ORX99891.1 - 0.031 14.1 6.2 0.054 13.3 6.2 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD PF00628.29 ORX99891.1 - 0.036 14.0 6.0 0.065 13.1 6.0 1.5 1 0 0 1 1 1 0 PHD-finger Zn_ribbon_17 PF17120.5 ORX99891.1 - 0.039 13.6 4.5 0.074 12.7 4.5 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.6 ORX99891.1 - 0.083 13.1 4.8 0.17 12.1 4.8 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING RINGv PF12906.7 ORX99891.1 - 0.13 12.4 3.6 0.27 11.4 3.6 1.6 1 1 0 1 1 1 0 RING-variant domain Prok-RING_4 PF14447.6 ORX99891.1 - 0.13 12.1 5.9 0.21 11.5 4.9 1.8 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 OAD_gamma PF04277.13 ORX99891.1 - 0.21 12.2 0.0 0.21 12.2 0.0 3.4 3 1 0 3 3 2 0 Oxaloacetate decarboxylase, gamma chain FANCL_C PF11793.8 ORX99891.1 - 0.77 10.0 3.8 2.1 8.6 3.8 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3H2C3 PF17122.5 ORX99891.1 - 2 8.5 5.9 4.2 7.5 5.9 1.6 1 1 0 1 1 1 0 Zinc-finger Prok-RING_1 PF14446.6 ORX99891.1 - 2.3 8.2 8.7 0.074 13.0 1.4 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 MinE PF03776.14 ORX99892.1 - 0.06 13.4 0.1 0.18 11.8 0.1 1.9 1 0 0 1 1 1 0 Septum formation topological specificity factor MinE SWIRM PF04433.17 ORX99892.1 - 0.12 12.7 0.1 0.36 11.2 0.1 1.8 1 0 0 1 1 1 0 SWIRM domain AAA PF00004.29 ORX99893.1 - 1.4e-17 64.4 0.0 2.8e-17 63.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 ORX99893.1 - 2.2e-05 24.7 2.1 0.0034 17.7 0.1 3.2 1 1 2 3 3 3 1 AAA domain AAA_16 PF13191.6 ORX99893.1 - 0.0013 19.2 0.7 0.0073 16.7 0.6 2.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 ORX99893.1 - 0.011 15.7 0.1 0.035 14.1 0.1 2.1 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 ORX99893.1 - 0.013 15.9 2.3 0.11 12.8 1.9 2.8 1 1 1 2 2 2 0 AAA domain AAA_30 PF13604.6 ORX99893.1 - 0.015 15.0 0.2 0.066 12.9 0.2 1.9 1 1 0 1 1 1 0 AAA domain Vps36_ESCRT-II PF11605.8 ORX99893.1 - 0.037 14.2 0.1 0.48 10.6 0.0 2.3 2 0 0 2 2 2 0 Vacuolar protein sorting protein 36 Vps36 Mg_chelatase PF01078.21 ORX99893.1 - 0.35 10.2 0.7 0.63 9.4 0.2 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Epimerase PF01370.21 ORX99895.1 - 2e-19 70.0 0.0 2.8e-19 69.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 ORX99895.1 - 4e-08 32.7 0.0 6.4e-08 32.0 0.0 1.4 1 1 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 ORX99895.1 - 5.5e-06 26.0 0.0 7.6e-06 25.5 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 ORX99895.1 - 4.6e-05 22.6 0.0 9.5e-05 21.5 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Sacchrp_dh_NADP PF03435.18 ORX99895.1 - 0.0052 17.1 0.0 0.01 16.1 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Topoisom_I PF01028.20 ORX99896.1 - 8.3e-97 323.0 4.7 8.3e-97 323.0 4.7 2.3 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.15 ORX99896.1 - 2e-96 321.6 3.8 2e-96 321.6 3.8 4.1 5 0 0 5 5 5 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topo_C_assoc PF14370.6 ORX99896.1 - 3.9e-34 116.4 1.5 1.2e-33 114.8 1.5 2.0 1 0 0 1 1 1 1 C-terminal topoisomerase domain ATP-synt PF00231.19 ORX99897.1 - 4.5e-79 266.1 1.1 5.6e-79 265.8 1.1 1.0 1 0 0 1 1 1 1 ATP synthase RNA_pol_A_bac PF01000.26 ORX99899.1 - 4.4e-23 81.8 0.0 8.4e-23 80.9 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 ORX99899.1 - 3.1e-19 68.2 0.0 5.6e-19 67.3 0.0 1.4 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Complex1_49kDa PF00346.19 ORX99900.1 - 2.8e-31 108.6 0.0 4.3e-31 108.0 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.19 ORX99900.1 - 0.0022 17.0 0.0 0.004 16.1 0.0 1.4 1 1 0 1 1 1 1 Nickel-dependent hydrogenase CbiJ PF02571.14 ORX99900.1 - 0.19 11.2 0.0 0.28 10.6 0.0 1.2 1 0 0 1 1 1 0 Precorrin-6x reductase CbiJ/CobK MFS_1 PF07690.16 ORX99948.1 - 9.7e-15 54.3 30.5 1.7e-14 53.5 30.5 1.5 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 ORX99948.1 - 1.4e-11 44.4 8.6 1.4e-11 44.4 8.6 2.1 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 DUF1345 PF07077.11 ORX99948.1 - 0.072 12.8 3.8 0.13 12.0 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1345) Ank_2 PF12796.7 ORX99949.1 - 2.2e-14 53.8 0.0 5.2e-08 33.4 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORX99949.1 - 3.4e-12 46.6 0.0 1.6e-06 28.6 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 ORX99949.1 - 1.1e-10 41.5 0.0 0.012 15.9 0.0 4.5 3 1 1 4 4 4 2 Ankyrin repeats (many copies) TPR_12 PF13424.6 ORX99949.1 - 7e-07 29.4 13.5 5.5e-06 26.6 3.4 3.8 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.6 ORX99949.1 - 1.1e-05 25.1 4.2 0.0011 18.8 0.7 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat Ank_3 PF13606.6 ORX99949.1 - 0.0006 20.1 4.1 2.5 9.0 0.0 4.8 6 0 0 6 6 5 2 Ankyrin repeat Ank PF00023.30 ORX99949.1 - 0.00072 19.9 0.0 5.4 7.6 0.0 4.2 4 0 0 4 4 4 1 Ankyrin repeat TPR_2 PF07719.17 ORX99949.1 - 0.00085 19.3 6.4 0.7 10.2 0.1 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat SPO22 PF08631.10 ORX99949.1 - 0.0034 16.9 2.3 0.007 15.9 2.3 1.5 1 0 0 1 1 1 1 Meiosis protein SPO22/ZIP4 like TPR_19 PF14559.6 ORX99949.1 - 0.0064 17.0 8.3 11 6.7 0.0 4.6 3 2 2 5 5 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 ORX99949.1 - 0.014 15.6 5.9 0.095 13.0 0.0 3.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 ORX99949.1 - 3 8.7 6.7 1.7 9.5 0.1 4.0 3 2 0 3 3 3 0 Tetratricopeptide repeat Proton_antipo_C PF01010.19 ORX99950.1 - 0.087 12.4 4.5 0.031 13.9 1.0 2.0 1 1 2 3 3 3 0 NADH-dehyrogenase subunit F, TMs, (complex I) C-terminus MSL2-CXC PF16682.5 ORX99950.1 - 0.42 10.8 6.5 0.54 10.4 1.0 2.6 2 0 0 2 2 2 0 CXC domain of E3 ubiquitin-protein ligase MSL2 OppC_N PF12911.7 ORX99950.1 - 2.9 7.9 6.1 0.96 9.5 0.4 2.5 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C Acetyltransf_1 PF00583.25 ORX99951.1 - 4.2e-17 62.5 0.0 5e-17 62.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ORX99951.1 - 2.3e-09 37.5 0.0 3.8e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ORX99951.1 - 2.5e-08 33.9 0.0 3.5e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ORX99951.1 - 2.2e-07 30.7 0.0 4.9e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 ORX99951.1 - 0.00011 22.8 0.0 0.00014 22.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 ORX99951.1 - 0.015 15.4 0.0 0.024 14.8 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase GNAT_acetyltran PF12746.7 ORX99951.1 - 0.033 13.7 0.0 0.048 13.2 0.0 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase Acetyltransf_9 PF13527.7 ORX99951.1 - 0.086 12.9 0.0 0.14 12.2 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 ORX99951.1 - 0.094 12.2 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 Putative acetyl-transferase Complex1_LYR PF05347.15 ORX99952.1 - 6.8e-05 22.8 3.9 0.00019 21.4 3.9 1.8 1 0 0 1 1 1 1 Complex 1 protein (LYR family) ADP_ribosyl_GH PF03747.14 ORX99952.1 - 0.17 11.6 0.7 0.3 10.8 0.3 1.5 2 0 0 2 2 2 0 ADP-ribosylglycohydrolase TilS PF09179.11 ORX99952.1 - 4.7 7.8 12.0 2.1 8.9 1.4 2.8 3 0 0 3 3 3 0 TilS substrate binding domain Ank_2 PF12796.7 ORX99953.1 - 1.4e-09 38.4 0.9 0.0015 19.1 0.1 3.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORX99953.1 - 5.9e-08 33.1 0.3 0.006 17.1 0.1 3.2 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORX99953.1 - 1e-07 31.7 3.2 0.038 14.5 0.0 4.6 4 1 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 ORX99953.1 - 1.9e-07 31.2 1.5 0.1 13.1 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 ORX99953.1 - 0.00031 21.0 2.3 1.1 9.7 0.0 3.7 3 1 1 4 4 4 2 Ankyrin repeats (many copies) KilA-N PF04383.13 ORX99953.1 - 0.00046 20.0 1.3 0.0041 17.0 0.2 2.7 2 1 0 2 2 2 1 KilA-N domain Pkinase PF00069.25 ORX99954.1 - 1.4e-46 159.0 0.0 1.7e-46 158.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX99954.1 - 4.7e-26 91.6 0.0 5.8e-26 91.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 ORX99954.1 - 0.0007 19.0 0.0 0.0012 18.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 ORX99954.1 - 0.0046 15.8 0.0 0.007 15.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 ORX99954.1 - 0.016 15.1 0.1 0.029 14.3 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 ORX99954.1 - 0.054 12.4 0.0 0.09 11.7 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Sugar_tr PF00083.24 ORX99956.1 - 6.9e-102 341.6 17.5 7.9e-102 341.4 17.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORX99956.1 - 1.4e-27 96.6 29.0 1.1e-22 80.5 14.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Alpha-L-AF_C PF06964.12 ORX99957.1 - 4.2e-31 108.3 0.2 6.3e-31 107.8 0.2 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain Glyco_hydro_44 PF12891.7 ORX99957.1 - 0.093 12.7 0.5 0.23 11.4 0.5 1.6 1 1 0 1 1 1 0 Glycoside hydrolase family 44 OPT PF03169.15 ORX99958.1 - 1.1e-16 60.7 0.3 1.1e-16 60.6 0.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Peptidase_M6 PF05547.11 ORX99959.1 - 3.3e-07 29.0 0.9 0.0015 16.9 1.6 2.1 2 0 0 2 2 2 2 Immune inhibitor A peptidase M6 AA_permease_2 PF13520.6 ORX99961.1 - 4.9e-62 210.1 50.9 6.4e-62 209.8 50.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ORX99961.1 - 8.6e-14 51.0 39.7 1.5e-13 50.1 39.7 1.4 1 1 0 1 1 1 1 Amino acid permease Phosphodiest PF01663.22 ORX99962.1 - 1.7e-24 87.1 0.0 2.7e-24 86.4 0.0 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 ORX99962.1 - 0.00029 20.3 0.0 0.00064 19.2 0.0 1.6 1 0 0 1 1 1 1 Sulfatase Glyoxalase PF00903.25 ORX99962.1 - 0.0019 18.4 0.0 0.53 10.5 0.0 2.3 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DUF229 PF02995.17 ORX99962.1 - 0.18 10.4 0.0 0.24 10.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Macro PF01661.21 ORX99963.1 - 1.1e-37 128.7 0.0 2.5e-37 127.5 0.0 1.6 2 0 0 2 2 2 1 Macro domain Glyco_hydro_47 PF01532.20 ORX99964.1 - 4.3e-112 375.3 0.0 5e-112 375.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF1772 PF08592.11 ORX99966.1 - 4e-31 108.1 1.6 5e-31 107.8 1.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) Pex2_Pex12 PF04757.14 ORX99966.1 - 0.053 13.1 0.8 0.076 12.6 0.8 1.3 1 0 0 1 1 1 0 Pex2 / Pex12 amino terminal region DUF2610 PF11020.8 ORX99966.1 - 0.15 12.0 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2610) DUF2189 PF09955.9 ORX99966.1 - 0.22 11.8 5.1 0.12 12.6 1.3 2.2 2 0 0 2 2 2 0 Predicted integral membrane protein (DUF2189) FAD_binding_3 PF01494.19 ORX99967.1 - 4.7e-14 52.4 0.1 1.8e-13 50.5 0.1 1.9 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 ORX99967.1 - 1.2e-07 31.6 2.5 0.0018 17.9 0.2 3.0 1 1 1 3 3 3 2 FAD dependent oxidoreductase HI0933_like PF03486.14 ORX99967.1 - 4.5e-05 22.3 0.1 0.00054 18.8 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 ORX99967.1 - 0.0021 17.2 0.3 0.007 15.5 0.1 1.9 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 ORX99967.1 - 0.0025 17.1 0.0 0.12 11.6 0.0 2.2 2 0 0 2 2 2 1 Thi4 family Pyr_redox_3 PF13738.6 ORX99967.1 - 0.0028 17.0 0.0 0.014 14.7 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 ORX99967.1 - 0.013 14.9 0.0 0.024 14.0 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ORX99967.1 - 0.014 15.6 0.1 0.035 14.3 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ORX99967.1 - 0.019 14.2 0.2 0.11 11.7 0.2 2.0 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF4467 PF14729.6 ORX99968.1 - 0.034 14.5 0.1 0.049 14.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function with cystatin-like fold (DUF4467) Methyltransf_11 PF08241.12 ORX99969.1 - 0.00056 20.5 0.0 0.0046 17.6 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORX99969.1 - 0.00082 20.0 0.1 0.019 15.7 0.1 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORX99969.1 - 0.057 13.3 0.0 0.091 12.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 ORX99969.1 - 0.066 14.0 0.2 2.5 8.9 0.1 2.8 1 1 1 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.6 ORX99969.1 - 0.15 11.8 0.1 2.3 8.0 0.1 2.1 1 1 0 1 1 1 0 Methyltransferase domain adh_short PF00106.25 ORX99970.1 - 7.2e-19 68.0 0.1 7e-11 41.9 0.0 2.1 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 ORX99970.1 - 5.3e-11 42.5 0.2 7.6e-10 38.7 0.0 1.9 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORX99970.1 - 4.6e-07 29.9 0.2 3.9e-06 26.9 0.0 2.0 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 ORX99970.1 - 0.00022 20.8 0.0 0.043 13.3 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 ORX99970.1 - 0.0012 18.0 0.0 0.0031 16.7 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Scytalone_dh PF02982.14 ORX99971.1 - 1.3e-70 236.3 0.2 1.6e-70 236.1 0.2 1.0 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.6 ORX99971.1 - 4.9e-06 26.7 0.1 6.3e-06 26.3 0.1 1.1 1 0 0 1 1 1 1 SnoaL-like domain HicA_toxin PF07927.12 ORX99972.1 - 9.6e-10 38.4 0.5 4.9e-09 36.1 0.0 2.3 2 0 0 2 2 2 1 HicA toxin of bacterial toxin-antitoxin, Retrotrans_gag PF03732.17 ORX99972.1 - 0.5 10.7 3.4 4.4 7.6 0.4 3.5 4 0 0 4 4 4 0 Retrotransposon gag protein Mito_carr PF00153.27 ORX99973.1 - 2.8e-57 190.6 3.5 1.1e-19 70.2 0.5 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein tRNA-synt_1g PF09334.11 ORY00001.1 - 1.1e-95 320.7 0.0 4.8e-94 315.3 0.0 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 ORY00001.1 - 4.3e-22 78.1 2.1 2.1e-09 36.2 0.0 3.8 2 2 2 4 4 4 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 ORY00001.1 - 2.6e-07 30.3 0.0 0.015 14.7 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 ORY00001.1 - 0.11 11.4 0.0 0.54 9.1 0.0 1.9 2 0 0 2 2 2 0 tRNA synthetases class I (K) NatB_MDM20 PF09797.9 ORY00002.1 - 1.2e-27 96.8 2.3 1.9e-26 92.9 2.3 2.2 1 1 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit Serine_rich PF08824.10 ORY00002.1 - 8.5e-05 22.6 0.1 0.00026 21.0 0.1 1.8 1 0 0 1 1 1 1 Serine rich protein interaction domain SWIB PF02201.18 ORY00003.1 - 3.7e-30 103.6 0.2 6.4e-30 102.9 0.2 1.4 1 0 0 1 1 1 1 SWIB/MDM2 domain DEK_C PF08766.11 ORY00003.1 - 2.9e-14 52.7 1.1 1.8e-13 50.2 0.3 2.3 2 0 0 2 2 2 1 DEK C terminal domain CDC27 PF09507.10 ORY00003.1 - 0.14 11.6 21.8 0.15 11.4 21.8 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Macoilin PF09726.9 ORY00003.1 - 0.21 10.1 11.1 0.25 9.9 11.1 1.1 1 0 0 1 1 1 0 Macoilin family GREB1 PF15782.5 ORY00003.1 - 1.2 6.2 7.7 1.4 6.0 7.7 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DTHCT PF08070.11 ORY00003.1 - 1.4 9.7 32.3 0.32 11.8 10.6 2.8 2 1 1 3 3 3 0 DTHCT (NUC029) region SRP-alpha_N PF04086.13 ORY00003.1 - 5.5 6.8 19.6 7.6 6.4 19.6 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Sec10 PF07393.11 ORY00004.1 - 5.3e-168 560.7 0.0 6.9e-168 560.3 0.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 DUF5302 PF17227.2 ORY00004.1 - 0.19 12.7 3.5 0.5 11.4 3.5 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5302) CFEM PF05730.11 ORY00005.1 - 8.6e-14 51.4 11.0 8.6e-14 51.4 11.0 2.0 2 1 0 2 2 2 1 CFEM domain DUF413 PF04219.12 ORY00006.1 - 0.0096 15.9 0.1 0.016 15.2 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF RIP PF00161.19 ORY00006.1 - 0.14 11.7 0.2 0.21 11.1 0.2 1.5 1 1 0 1 1 1 0 Ribosome inactivating protein TraQ PF09679.10 ORY00006.1 - 1.5 8.8 3.9 14 5.6 3.9 2.1 1 1 0 1 1 1 0 Type-F conjugative transfer system pilin chaperone (TraQ) DUF3602 PF12223.8 ORY00007.1 - 2e-16 60.3 11.7 6.2e-14 52.4 1.0 2.7 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) WD40 PF00400.32 ORY00008.1 - 5.8e-15 55.4 6.7 0.0013 19.5 0.0 5.6 5 0 0 5 5 5 5 WD domain, G-beta repeat Nucleoporin_N PF08801.11 ORY00008.1 - 0.14 10.9 0.0 8 5.1 0.0 2.4 3 0 0 3 3 3 0 Nup133 N terminal like AAA PF00004.29 ORY00009.1 - 9e-43 145.9 0.0 1.5e-42 145.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 ORY00009.1 - 1e-10 41.4 0.0 3.8e-10 39.6 0.0 1.9 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 ORY00009.1 - 1.4e-10 40.8 0.2 3.2e-10 39.7 0.1 1.7 2 0 0 2 2 1 1 AAA+ lid domain AAA_16 PF13191.6 ORY00009.1 - 8.8e-08 32.7 0.0 5.7e-05 23.6 0.1 2.9 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 ORY00009.1 - 1.8e-06 28.0 0.1 3.2e-05 23.9 0.1 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 ORY00009.1 - 2.6e-06 27.6 0.0 9.4e-06 25.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 ORY00009.1 - 7.2e-06 25.8 0.0 1.5e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 ORY00009.1 - 0.00018 21.8 0.1 0.0036 17.6 0.1 2.4 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 ORY00009.1 - 0.00039 19.7 0.0 0.00085 18.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 ORY00009.1 - 0.00087 19.8 0.1 0.0028 18.2 0.0 1.9 2 1 0 2 2 1 1 AAA domain AAA_7 PF12775.7 ORY00009.1 - 0.0012 18.4 0.0 0.0024 17.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region TIP49 PF06068.13 ORY00009.1 - 0.0024 17.1 0.0 0.0044 16.3 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 ORY00009.1 - 0.0034 17.5 0.0 0.01 16.0 0.0 1.9 2 0 0 2 2 1 1 AAA domain Mg_chelatase PF01078.21 ORY00009.1 - 0.0043 16.5 0.0 0.008 15.6 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TsaE PF02367.17 ORY00009.1 - 0.0047 16.9 0.0 0.0093 16.0 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 ORY00009.1 - 0.0061 16.9 0.0 0.012 16.0 0.0 1.5 1 0 0 1 1 1 1 RNA helicase IstB_IS21 PF01695.17 ORY00009.1 - 0.0061 16.3 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.6 ORY00009.1 - 0.0073 16.4 0.0 0.017 15.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 ORY00009.1 - 0.0079 15.9 0.0 0.028 14.1 0.0 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.11 ORY00009.1 - 0.013 15.3 0.0 0.03 14.2 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 ORY00009.1 - 0.023 14.1 0.1 0.13 11.6 0.0 2.2 2 0 0 2 2 2 0 KaiC AAA_24 PF13479.6 ORY00009.1 - 0.027 14.2 0.0 0.057 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 ORY00009.1 - 0.039 13.7 0.0 0.11 12.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain Prot_ATP_OB_N PF17758.1 ORY00009.1 - 0.04 13.6 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 Proteasomal ATPase OB N-terminal domain NACHT PF05729.12 ORY00009.1 - 0.054 13.4 0.1 0.15 12.0 0.0 1.7 2 0 0 2 2 2 0 NACHT domain PhoH PF02562.16 ORY00009.1 - 0.066 12.7 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_28 PF13521.6 ORY00009.1 - 0.089 13.0 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 ORY00009.1 - 0.093 12.3 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 ORY00009.1 - 0.12 12.1 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 ORY00009.1 - 0.13 11.6 0.0 0.26 10.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Parvo_NS1 PF01057.17 ORY00009.1 - 0.13 11.3 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 eIF-1a PF01176.19 ORY00009.1 - 0.16 11.8 0.0 0.3 10.9 0.0 1.4 1 0 0 1 1 1 0 Translation initiation factor 1A / IF-1 Acetyltransf_3 PF13302.7 ORY00010.1 - 9.3e-26 91.2 0.0 1.2e-25 90.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 ORY00010.1 - 4.5e-05 23.2 0.6 0.16 11.7 0.7 3.0 3 0 0 3 3 3 2 Acetyltransferase (GNAT) domain FR47 PF08445.10 ORY00010.1 - 0.0088 16.0 0.0 0.23 11.5 0.0 2.2 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_4 PF13420.7 ORY00010.1 - 0.059 13.5 0.1 6.9 6.8 0.0 2.4 2 1 1 3 3 3 0 Acetyltransferase (GNAT) domain DUF2014 PF09427.10 ORY00011.1 - 0.039 13.3 0.2 0.05 13.0 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2014) 3Beta_HSD PF01073.19 ORY00012.1 - 5.8e-56 189.6 0.0 6.8e-56 189.3 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 ORY00012.1 - 1.6e-35 122.7 0.0 2e-35 122.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 ORY00012.1 - 1.3e-17 63.8 0.0 1.9e-17 63.3 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 ORY00012.1 - 1.3e-16 61.0 0.0 2.9e-16 59.8 0.0 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 ORY00012.1 - 3e-13 49.5 0.1 2e-08 33.7 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 ORY00012.1 - 1e-11 45.1 0.0 1.4e-11 44.6 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 ORY00012.1 - 1.6e-10 40.6 0.3 7.5e-09 35.1 0.2 2.6 2 2 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.10 ORY00012.1 - 1.3e-06 28.4 0.2 7.8e-06 25.9 0.2 1.9 1 1 0 1 1 1 1 KR domain NmrA PF05368.13 ORY00012.1 - 0.00045 19.9 0.3 0.00069 19.2 0.3 1.3 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.25 ORY00012.1 - 0.0026 17.2 0.1 0.0043 16.5 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase DapB_N PF01113.20 ORY00012.1 - 0.014 15.6 0.0 0.037 14.1 0.0 1.8 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus rOmpB PF12334.8 ORY00012.1 - 0.02 14.3 2.0 0.15 11.5 0.1 2.2 1 1 1 2 2 2 0 Rickettsia outer membrane protein B TrkA_N PF02254.18 ORY00012.1 - 0.03 14.6 0.0 0.056 13.7 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain ATP11 PF06644.11 ORY00014.1 - 9.9e-90 301.0 0.0 1.1e-89 300.8 0.0 1.0 1 0 0 1 1 1 1 ATP11 protein ArfGap PF01412.18 ORY00015.1 - 9.1e-35 119.3 1.2 2.1e-34 118.1 0.0 2.2 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf BAR_3 PF16746.5 ORY00015.1 - 2.7e-20 73.1 17.1 4.4e-20 72.4 17.1 1.2 1 0 0 1 1 1 1 BAR domain of APPL family PH PF00169.29 ORY00015.1 - 4.5e-12 46.4 0.2 1.4e-11 44.8 0.2 1.9 1 0 0 1 1 1 1 PH domain TF_Zn_Ribbon PF08271.12 ORY00015.1 - 0.057 12.9 0.0 0.15 11.6 0.0 1.7 1 0 0 1 1 1 0 TFIIB zinc-binding FdhE PF04216.12 ORY00015.1 - 6.1 6.6 7.2 6.3 6.6 1.0 2.5 1 1 1 2 2 2 0 Protein involved in formate dehydrogenase formation eIF2A PF08662.11 ORY00016.1 - 7.3e-39 133.6 4.6 6.5e-36 124.0 0.2 4.3 4 2 0 4 4 4 2 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.22 ORY00016.1 - 0.00094 19.0 0.0 0.0021 17.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.32 ORY00016.1 - 0.078 13.9 0.4 21 6.2 0.0 4.2 4 0 0 4 4 4 0 WD domain, G-beta repeat Syja_N PF02383.18 ORY00017.1 - 1.5e-77 261.1 0.0 2.3e-77 260.4 0.0 1.3 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.23 ORY00017.1 - 1.8e-08 34.2 0.0 4.2e-08 33.0 0.0 1.7 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RhoGAP PF00620.27 ORY00019.1 - 2.6e-16 59.8 0.0 8.4e-16 58.1 0.0 1.8 2 0 0 2 2 2 1 RhoGAP domain DEP PF00610.21 ORY00019.1 - 1.9e-10 40.6 0.0 4.1e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) FCH PF00611.23 ORY00019.1 - 2.4e-09 37.4 0.0 1.5e-08 34.8 0.0 2.3 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain MAS20 PF02064.15 ORY00019.1 - 0.12 12.5 0.1 2.8 8.0 0.1 2.6 2 0 0 2 2 2 0 MAS20 protein import receptor Prenyltrans PF00432.21 ORY00020.1 - 1.1e-30 105.0 5.4 2.2e-06 27.3 0.1 5.4 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 ORY00020.1 - 0.085 11.9 0.0 0.26 10.3 0.0 1.8 2 1 0 2 2 2 0 Squalene-hopene cyclase C-terminal domain DUF2059 PF09832.9 ORY00020.1 - 0.13 12.4 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2059) DUF3710 PF12502.8 ORY00020.1 - 0.18 11.4 0.1 0.31 10.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3710) Nop25 PF09805.9 ORY00021.1 - 1.1e-41 142.5 8.3 1.1e-41 142.5 8.3 2.6 2 1 0 2 2 2 1 Nucleolar protein 12 (25kDa) Tropomyosin_1 PF12718.7 ORY00022.1 - 1.4e-51 174.4 27.9 1.6e-51 174.2 27.9 1.0 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.20 ORY00022.1 - 4.1e-09 36.2 27.7 2e-05 24.1 14.7 2.9 1 1 1 2 2 2 2 Tropomyosin GAS PF13851.6 ORY00022.1 - 0.0023 17.3 25.2 0.033 13.6 16.2 2.3 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding KLRAQ PF10205.9 ORY00022.1 - 0.0054 16.9 5.9 0.0054 16.9 5.9 2.3 1 1 1 2 2 2 1 Predicted coiled-coil domain-containing protein FlaC_arch PF05377.11 ORY00022.1 - 0.0056 17.1 13.4 0.029 14.7 3.1 3.4 3 0 0 3 3 3 1 Flagella accessory protein C (FlaC) HMMR_N PF15905.5 ORY00022.1 - 0.0069 15.9 26.5 0.01 15.3 26.5 1.3 1 1 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal DUF3450 PF11932.8 ORY00022.1 - 0.0098 15.2 24.1 0.024 14.0 8.7 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3450) ATG16 PF08614.11 ORY00022.1 - 0.016 15.4 27.8 0.38 11.0 10.2 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Fib_alpha PF08702.10 ORY00022.1 - 0.017 15.3 11.6 0.059 13.6 2.7 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family CENP-F_leu_zip PF10473.9 ORY00022.1 - 0.02 14.9 30.2 0.043 13.9 4.3 3.1 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fez1 PF06818.15 ORY00022.1 - 0.02 15.4 22.7 0.017 15.6 21.2 1.5 1 1 0 1 1 1 0 Fez1 ADIP PF11559.8 ORY00022.1 - 0.023 14.8 23.5 0.28 11.3 9.0 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Jnk-SapK_ap_N PF09744.9 ORY00022.1 - 0.027 14.7 27.3 0.037 14.2 22.9 2.0 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 TMF_TATA_bd PF12325.8 ORY00022.1 - 0.04 14.1 21.7 1.2 9.4 10.6 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding CLZ PF16526.5 ORY00022.1 - 0.061 13.7 21.3 0.17 12.3 2.1 3.8 1 1 3 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels KxDL PF10241.9 ORY00022.1 - 0.065 13.5 1.1 0.065 13.5 1.1 3.4 1 1 2 3 3 3 0 Uncharacterized conserved protein DUF724 PF05266.14 ORY00022.1 - 0.067 13.0 21.4 0.24 11.2 7.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Spc7 PF08317.11 ORY00022.1 - 0.073 11.9 29.5 0.46 9.3 11.4 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein KASH_CCD PF14662.6 ORY00022.1 - 0.075 12.9 26.0 0.43 10.4 8.2 2.2 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH BLOC1_2 PF10046.9 ORY00022.1 - 0.091 13.1 19.5 2.2 8.6 0.9 3.1 1 1 3 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4200 PF13863.6 ORY00022.1 - 0.1 13.0 29.6 0.089 13.2 8.3 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) Uso1_p115_C PF04871.13 ORY00022.1 - 0.11 12.8 31.4 0.68 10.3 12.2 2.3 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Cep57_CLD_2 PF14197.6 ORY00022.1 - 0.13 12.4 22.6 0.55 10.3 1.7 3.7 3 1 0 3 3 3 0 Centrosome localisation domain of PPC89 UPF0242 PF06785.11 ORY00022.1 - 0.13 12.3 28.3 0.37 10.9 10.9 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus CENP-K PF11802.8 ORY00022.1 - 0.15 11.6 18.4 0.41 10.2 18.4 1.7 1 1 0 1 1 1 0 Centromere-associated protein K DUF1664 PF07889.12 ORY00022.1 - 0.16 12.0 12.8 0.18 11.9 2.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DHR10 PF18595.1 ORY00022.1 - 0.16 12.0 29.0 0.13 12.4 9.0 2.5 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain DUF812 PF05667.11 ORY00022.1 - 0.16 10.8 25.5 0.3 9.9 25.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF812) DUF3584 PF12128.8 ORY00022.1 - 0.24 8.9 20.9 0.29 8.6 20.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Sec20 PF03908.13 ORY00022.1 - 0.25 11.3 6.2 0.95 9.4 0.7 2.6 2 1 0 2 2 2 0 Sec20 Lebercilin PF15619.6 ORY00022.1 - 0.27 10.9 28.1 1 9.0 15.7 2.3 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease HOOK PF05622.12 ORY00022.1 - 0.27 9.3 22.3 0.34 9.0 22.3 1.1 1 0 0 1 1 1 0 HOOK protein APG6_N PF17675.1 ORY00022.1 - 0.35 11.4 35.1 1.5 9.4 12.8 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region ERM PF00769.19 ORY00022.1 - 0.35 10.6 32.7 11 5.8 33.5 1.9 1 1 0 1 1 1 0 Ezrin/radixin/moesin family EzrA PF06160.12 ORY00022.1 - 0.36 8.9 21.5 0.16 10.1 5.8 2.0 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA TMF_DNA_bd PF12329.8 ORY00022.1 - 0.37 10.8 33.4 0.55 10.3 14.2 3.0 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding YjcZ PF13990.6 ORY00022.1 - 0.38 10.1 6.9 0.16 11.3 3.7 1.7 1 1 1 2 2 2 0 YjcZ-like protein ZapB PF06005.12 ORY00022.1 - 0.41 11.1 32.4 2.4 8.6 4.5 3.7 2 2 2 4 4 4 0 Cell division protein ZapB IFT46_B_C PF12317.8 ORY00022.1 - 0.46 10.2 8.2 0.061 13.0 3.2 1.8 1 1 1 2 2 2 0 Intraflagellar transport complex B protein 46 C terminal TACC_C PF05010.14 ORY00022.1 - 0.58 9.9 22.1 3.2 7.5 14.8 2.5 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF4407 PF14362.6 ORY00022.1 - 0.75 9.1 19.9 3.8 6.8 19.9 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) bZIP_1 PF00170.21 ORY00022.1 - 0.84 9.8 26.4 0.35 11.0 6.3 4.1 3 1 1 4 4 4 0 bZIP transcription factor E2F_CC-MB PF16421.5 ORY00022.1 - 0.9 9.9 10.8 4.8 7.6 0.1 2.9 2 1 0 2 2 2 0 E2F transcription factor CC-MB domain FH2 PF02181.23 ORY00022.1 - 0.96 8.5 14.9 0.72 8.9 6.9 2.3 1 1 1 2 2 2 0 Formin Homology 2 Domain Syntaxin_2 PF14523.6 ORY00022.1 - 0.98 9.8 10.9 0.33 11.4 7.0 2.0 1 1 1 2 2 2 0 Syntaxin-like protein DUF4201 PF13870.6 ORY00022.1 - 0.98 9.1 24.0 2.5 7.8 7.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) Rootletin PF15035.6 ORY00022.1 - 1.4 8.9 24.1 0.6 10.1 6.1 2.0 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion HAP1_N PF04849.13 ORY00022.1 - 1.4 8.1 23.1 5.1 6.2 23.1 2.2 1 1 0 1 1 1 0 HAP1 N-terminal conserved region NPV_P10 PF05531.12 ORY00022.1 - 1.4 9.4 6.2 21 5.6 0.2 3.4 2 2 2 4 4 4 0 Nucleopolyhedrovirus P10 protein SlyX PF04102.12 ORY00022.1 - 1.6 9.4 17.9 4.3 8.0 2.1 3.2 1 1 3 4 4 4 0 SlyX LPP PF04728.13 ORY00022.1 - 1.7 9.1 13.1 0.42 11.0 0.7 3.5 4 0 0 4 4 3 0 Lipoprotein leucine-zipper DUF2937 PF11157.8 ORY00022.1 - 1.8 8.3 8.1 4.1 7.1 2.9 2.9 1 1 3 4 4 4 0 Protein of unknown function (DUF2937) Dor1 PF04124.12 ORY00022.1 - 1.8 7.2 12.7 0.53 8.9 4.1 2.1 1 1 1 2 2 2 0 Dor1-like family DUF5595 PF18077.1 ORY00022.1 - 2 8.6 17.8 0.062 13.4 5.1 3.2 3 1 0 3 3 3 0 Domain of unknown function (DUF5595) TMCO5 PF14992.6 ORY00022.1 - 2.2 7.8 25.8 2 7.9 16.3 2.0 1 1 1 2 2 2 0 TMCO5 family Laminin_II PF06009.12 ORY00022.1 - 2.5 8.1 14.5 0.2 11.6 2.4 2.2 1 1 1 2 2 2 0 Laminin Domain II Fungal_TACC PF12709.7 ORY00022.1 - 2.6 8.5 24.8 3.3 8.2 6.6 3.6 2 2 1 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins TPR_MLP1_2 PF07926.12 ORY00022.1 - 3.2 7.8 33.8 5.4 7.1 4.1 3.2 1 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein CtIP_N PF10482.9 ORY00022.1 - 3.3 7.8 19.6 0.14 12.2 5.1 2.8 1 1 1 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain Fmp27_WPPW PF10359.9 ORY00022.1 - 3.7 6.3 22.1 4.8e+02 -0.7 22.1 2.0 1 1 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF4472 PF14739.6 ORY00022.1 - 3.7 8.3 23.6 4 8.2 7.9 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) Atg14 PF10186.9 ORY00022.1 - 3.8 6.5 22.9 1.3 8.0 6.6 2.0 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 FUSC PF04632.12 ORY00022.1 - 4.2 5.8 5.3 4.9 5.5 5.3 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family GvpL_GvpF PF06386.11 ORY00022.1 - 5 7.0 15.3 0.68 9.8 11.1 1.6 1 1 1 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF Ax_dynein_light PF10211.9 ORY00022.1 - 5.2 7.0 27.6 5.2 7.0 2.5 3.5 1 1 2 3 3 3 0 Axonemal dynein light chain BRE1 PF08647.11 ORY00022.1 - 6.1 7.0 29.8 4.9 7.3 5.7 2.9 1 1 2 3 3 3 0 BRE1 E3 ubiquitin ligase AAA_13 PF13166.6 ORY00022.1 - 7.7 5.0 20.3 39 2.7 20.3 1.8 1 1 0 1 1 1 0 AAA domain HemX PF04375.14 ORY00022.1 - 9.2 5.4 19.2 5.6 6.1 4.8 2.3 1 1 1 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase XhlA PF10779.9 ORY00022.1 - 9.3 6.5 22.6 5.2 7.3 1.7 3.8 2 2 3 5 5 5 0 Haemolysin XhlA Swi5 PF07061.11 ORY00022.1 - 9.6 6.4 25.2 3.9 7.6 1.1 3.9 1 1 3 4 4 4 0 Swi5 Pro_isomerase PF00160.21 ORY00024.1 - 1.4e-49 168.4 0.3 3e-49 167.3 0.3 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 ORY00024.1 - 4e-12 46.4 1.8 0.00013 22.7 0.0 5.0 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY00024.1 - 0.00062 20.0 0.0 0.03 14.6 0.0 2.9 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain bMG3 PF11974.8 ORY00024.1 - 0.004 17.2 0.0 2.2 8.4 0.0 2.5 2 0 0 2 2 2 2 Bacterial alpha-2-macroglobulin MG3 domain Ge1_WD40 PF16529.5 ORY00024.1 - 0.0045 16.0 0.5 0.26 10.2 0.1 2.4 1 1 1 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF5643 PF18705.1 ORY00024.1 - 0.033 14.2 0.1 0.11 12.5 0.1 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5643) DUF4115 PF13464.6 ORY00024.1 - 0.12 12.5 0.1 46 4.3 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4115) Ring_hydroxyl_A PF00848.19 ORY00025.1 - 0.022 14.7 0.0 0.047 13.7 0.0 1.5 1 0 0 1 1 1 0 Ring hydroxylating alpha subunit (catalytic domain) Methyltransf_3 PF01596.17 ORY00026.1 - 9.8e-13 47.8 0.0 1.4e-12 47.3 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 ORY00026.1 - 6.6e-11 43.2 0.0 1.1e-10 42.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DHQ_synthase PF01761.20 ORY00027.1 - 3.9e-53 180.3 0.0 5.3e-53 179.8 0.0 1.1 1 0 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.6 ORY00027.1 - 3.1e-12 46.7 0.0 4.6e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH PF00465.19 ORY00027.1 - 0.006 15.5 0.0 0.0094 14.8 0.0 1.4 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Proteasome PF00227.26 ORY00028.1 - 2.9e-38 131.3 0.0 3.4e-38 131.1 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Enolase_C PF00113.22 ORY00029.1 - 1.4e-154 513.6 0.0 1.9e-154 513.2 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 ORY00029.1 - 1.4e-57 193.4 0.5 2.4e-57 192.7 0.5 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 ORY00029.1 - 1.8e-07 31.0 0.0 3.7e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 ORY00029.1 - 0.018 14.2 1.5 0.93 8.6 0.2 2.9 3 0 0 3 3 3 0 Methylaspartate ammonia-lyase C-terminus Mid1 PF12929.7 ORY00032.1 - 0.095 11.9 0.1 0.13 11.4 0.1 1.1 1 0 0 1 1 1 0 Stretch-activated Ca2+-permeable channel component DUF2700 PF10912.8 ORY00033.1 - 0.00077 19.5 4.5 0.45 10.5 0.1 2.7 3 0 0 3 3 3 2 Protein of unknown function (DUF2700) MARVEL PF01284.23 ORY00033.1 - 0.008 16.2 8.8 0.008 16.2 8.8 1.9 1 1 1 2 2 2 1 Membrane-associating domain EphA2_TM PF14575.6 ORY00033.1 - 0.022 15.6 0.1 0.84 10.6 0.0 2.9 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain TMEM192 PF14802.6 ORY00033.1 - 0.054 12.6 2.2 4.1 6.4 0.2 2.2 2 0 0 2 2 2 0 TMEM192 family DUF2070 PF09843.9 ORY00033.1 - 0.071 11.4 2.5 0.1 10.9 2.5 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Yip1 PF04893.17 ORY00033.1 - 0.09 12.5 4.3 0.16 11.7 4.0 1.6 1 1 0 1 1 1 0 Yip1 domain Cation_efflux PF01545.21 ORY00033.1 - 0.3 10.8 4.1 0.12 12.0 1.4 1.6 2 1 0 2 2 2 0 Cation efflux family DUF1772 PF08592.11 ORY00033.1 - 0.99 9.7 4.9 1.6 9.0 4.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1772) 7TMR-DISM_7TM PF07695.11 ORY00033.1 - 0.99 9.3 9.6 0.12 12.2 5.1 1.7 2 0 0 2 2 2 0 7TM diverse intracellular signalling DUF202 PF02656.15 ORY00033.1 - 1.1 9.8 6.6 11 6.6 3.6 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF202) DUF3290 PF11694.8 ORY00033.1 - 2.4 8.1 3.9 7.9 6.4 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3290) Ribosomal_L5_C PF00673.21 ORY00035.1 - 1.3e-22 79.7 0.0 1.9e-22 79.2 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 ORY00035.1 - 3.4e-20 72.1 0.0 7.3e-20 71.1 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L5 LSM PF01423.22 ORY00036.1 - 8.5e-18 63.8 0.0 1e-17 63.5 0.0 1.1 1 0 0 1 1 1 1 LSM domain MPC PF03650.13 ORY00037.1 - 2.8e-36 124.0 0.0 3.2e-36 123.8 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers AAA PF00004.29 ORY00038.1 - 2.7e-44 150.8 0.0 4.7e-44 150.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 ORY00038.1 - 3.5e-10 39.5 0.8 2.1e-09 37.0 0.0 2.3 2 0 0 2 2 2 1 AAA+ lid domain AAA_16 PF13191.6 ORY00038.1 - 4.2e-05 24.0 0.4 0.024 15.0 0.1 2.8 1 1 1 2 2 2 2 AAA ATPase domain RuvB_N PF05496.12 ORY00038.1 - 0.00076 19.3 0.0 0.0032 17.2 0.0 2.0 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 ORY00038.1 - 0.0056 16.3 0.1 0.36 10.4 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.14 ORY00038.1 - 0.009 16.1 0.0 0.024 14.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 ORY00038.1 - 0.018 15.3 0.1 1.1 9.5 0.2 2.9 1 1 2 3 3 3 0 AAA domain AAA_33 PF13671.6 ORY00038.1 - 0.018 15.2 0.0 0.047 13.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 ORY00038.1 - 0.027 14.9 1.0 0.57 10.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 ORY00038.1 - 0.078 13.0 0.1 0.41 10.6 0.1 2.2 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 ORY00038.1 - 0.085 12.2 0.1 0.21 10.9 0.1 1.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI NACHT PF05729.12 ORY00038.1 - 0.11 12.5 0.2 4.1 7.3 0.1 2.4 2 0 0 2 2 2 0 NACHT domain DUF3433 PF11915.8 ORY00087.1 - 2.3e-31 108.1 24.1 5.5e-21 74.8 2.8 4.0 4 0 0 4 4 4 2 Protein of unknown function (DUF3433) DUF2160 PF09928.9 ORY00087.1 - 0.00016 21.9 1.3 0.001 19.4 1.3 2.4 1 0 0 1 1 1 1 Predicted small integral membrane protein (DUF2160) CHASE PF03924.13 ORY00087.1 - 0.15 12.0 0.2 0.31 10.9 0.2 1.4 1 0 0 1 1 1 0 CHASE domain LeuA_dimer PF08502.10 ORY00088.1 - 1.3e-22 80.1 0.4 3e-22 79.0 0.4 1.6 1 1 0 1 1 1 1 LeuA allosteric (dimerisation) domain HMGL-like PF00682.19 ORY00088.1 - 8.4e-14 51.8 0.4 3.1e-13 49.9 0.1 1.9 2 0 0 2 2 2 1 HMGL-like Glyco_hydro_7 PF00840.20 ORY00089.1 - 5.6e-85 285.7 21.8 5.8e-28 97.8 1.0 5.0 1 1 3 4 4 4 4 Glycosyl hydrolase family 7 HET PF06985.11 ORY00090.1 - 4.1e-16 59.6 0.1 4.8e-16 59.4 0.1 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SnoaL_4 PF13577.6 ORY00093.1 - 1.1e-57 193.6 1.0 1.8e-22 79.8 0.2 3.3 3 0 0 3 3 3 3 SnoaL-like domain SnoaL_2 PF12680.7 ORY00093.1 - 9e-05 23.1 0.4 0.63 10.7 0.1 3.0 3 1 0 3 3 3 2 SnoaL-like domain p450 PF00067.22 ORY00094.1 - 1.2e-63 215.5 0.0 1.5e-63 215.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HSP20 PF00011.21 ORY00096.1 - 6.9e-17 61.5 2.4 2.1e-09 37.5 0.0 2.4 2 0 0 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 ORY00096.1 - 1.5e-05 24.5 0.0 0.097 12.2 0.0 2.4 2 0 0 2 2 2 2 HSP20-like domain found in ArsA eIF3_subunit PF08597.10 ORY00096.1 - 0.019 14.9 3.1 0.019 14.9 3.1 1.9 1 1 1 2 2 2 0 Translation initiation factor eIF3 subunit Copper-bind PF00127.20 ORY00097.1 - 0.0041 17.5 0.7 0.043 14.2 0.7 2.2 1 1 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Cu_bind_like PF02298.17 ORY00097.1 - 0.0047 16.9 0.8 0.011 15.7 0.8 1.6 1 1 0 1 1 1 1 Plastocyanin-like domain MFS_1 PF07690.16 ORY00098.1 - 9.1e-29 100.5 33.8 9.1e-29 100.5 33.8 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily OspD PF03207.13 ORY00099.1 - 0.022 14.1 0.7 0.031 13.6 0.7 1.2 1 0 0 1 1 1 0 Borrelia outer surface protein D (OspD) DUF1489 PF07370.11 ORY00099.1 - 0.045 13.5 0.5 0.087 12.5 0.1 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1489) Aa_trans PF01490.18 ORY00100.1 - 8e-79 265.2 21.9 9.6e-79 265.0 21.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 ORY00100.1 - 1.2e-05 24.6 10.3 1.2e-05 24.6 10.3 2.0 3 0 0 3 3 3 1 Tryptophan/tyrosine permease family HET PF06985.11 ORY00101.1 - 9.3e-25 87.7 0.0 1.6e-24 86.9 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Tachystatin_B PF11478.8 ORY00102.1 - 0.99 9.4 6.7 3.1 7.8 6.7 1.9 1 0 0 1 1 1 0 Antimicrobial chitin binding protein tachystatin B Lustrin_cystein PF14625.6 ORY00102.1 - 5.2 7.5 26.3 1.5 9.2 12.7 2.9 1 1 1 2 2 2 0 Lustrin, cysteine-rich repeated domain Ran-binding PF05508.11 ORY00149.1 - 2.3e-121 404.6 0.0 2.9e-121 404.2 0.0 1.1 1 0 0 1 1 1 1 RanGTP-binding protein GTP_EFTU PF00009.27 ORY00150.1 - 3.8e-42 144.0 0.0 6.9e-42 143.2 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 ORY00150.1 - 4.3e-29 101.1 0.0 8.7e-29 100.1 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 ORY00150.1 - 4.5e-06 26.9 0.1 1e-05 25.8 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 ORY00150.1 - 0.0034 17.4 0.1 0.021 14.9 0.1 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase TFIIA PF03153.13 ORY00150.1 - 0.9 9.5 20.7 1.7 8.5 20.7 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DEAD PF00270.29 ORY00152.1 - 5.4e-42 143.5 0.0 1.2e-41 142.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY00152.1 - 6.7e-27 94.0 0.0 1.6e-26 92.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY00152.1 - 0.00022 21.3 0.2 0.00098 19.2 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 ORY00152.1 - 0.003 17.8 0.3 0.14 12.4 0.1 2.9 2 1 0 2 2 2 1 AAA domain AAA_11 PF13086.6 ORY00152.1 - 0.0098 15.7 6.1 6 6.6 3.5 3.5 3 0 0 3 3 3 2 AAA domain DUF1266 PF06889.11 ORY00152.1 - 5.8 6.9 6.5 11 6.0 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1266) FtsJ PF01728.19 ORY00153.1 - 1.2e-63 214.4 0.0 1.5e-63 214.1 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF4448 PF14610.6 ORY00154.1 - 0.047 13.5 0.0 0.066 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) MGC-24 PF05283.11 ORY00154.1 - 0.051 14.0 3.6 0.049 14.1 2.3 1.7 1 1 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Syndecan PF01034.20 ORY00154.1 - 0.12 12.3 0.9 0.21 11.5 0.9 1.4 1 0 0 1 1 1 0 Syndecan domain Orf78 PF06024.12 ORY00154.1 - 0.19 12.0 0.0 0.31 11.4 0.0 1.2 1 0 0 1 1 1 0 Orf78 (ac78) Trypan_PARP PF05887.11 ORY00155.1 - 0.0016 18.4 5.8 0.0027 17.7 5.8 1.3 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) Herpes_gE PF02480.16 ORY00155.1 - 0.0037 16.1 0.0 0.0052 15.6 0.0 1.1 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E Glyco_hydro_61 PF03443.14 ORY00156.1 - 2.4e-33 115.8 0.0 2.8e-33 115.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 SNF2_N PF00176.23 ORY00157.1 - 4.9e-57 193.2 0.0 6.9e-57 192.7 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ORY00157.1 - 8.6e-12 45.4 0.0 1.7e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Methyltrans_RNA PF04452.14 ORY00157.1 - 0.039 13.3 0.0 0.076 12.3 0.0 1.4 1 0 0 1 1 1 0 RNA methyltransferase WD40 PF00400.32 ORY00158.1 - 2e-28 98.1 15.5 1e-07 32.5 1.6 7.8 7 0 0 7 7 7 5 WD domain, G-beta repeat NACHT PF05729.12 ORY00158.1 - 4.9e-08 33.1 0.2 9.9e-08 32.1 0.0 1.6 2 0 0 2 2 1 1 NACHT domain AAA_22 PF13401.6 ORY00158.1 - 1.3e-06 28.8 0.0 9.7e-06 25.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 ORY00158.1 - 9.5e-05 22.8 0.4 0.00074 19.9 0.0 2.6 3 0 0 3 3 3 1 AAA ATPase domain PQQ_2 PF13360.6 ORY00158.1 - 0.00064 19.4 0.1 0.079 12.5 0.0 2.3 2 0 0 2 2 2 1 PQQ-like domain RNA_helicase PF00910.22 ORY00158.1 - 0.0069 16.8 0.0 0.016 15.6 0.0 1.6 1 0 0 1 1 1 1 RNA helicase KinB_sensor PF16767.5 ORY00158.1 - 0.011 16.2 1.4 0.56 10.7 0.1 2.8 3 0 0 3 3 2 0 Sensor domain of alginate biosynthesis sensor protein KinB AAA PF00004.29 ORY00158.1 - 0.011 16.1 0.0 0.03 14.7 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MeaB PF03308.16 ORY00158.1 - 0.018 14.1 0.0 0.035 13.1 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NB-ARC PF00931.22 ORY00158.1 - 0.026 13.7 0.1 0.34 10.0 0.0 2.3 1 1 1 2 2 2 0 NB-ARC domain AAA_18 PF13238.6 ORY00158.1 - 0.039 14.5 0.6 1.3 9.6 0.0 3.0 1 1 1 2 2 2 0 AAA domain DUF2075 PF09848.9 ORY00158.1 - 0.089 12.0 0.0 0.51 9.5 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_7 PF12775.7 ORY00158.1 - 0.093 12.2 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Ge1_WD40 PF16529.5 ORY00158.1 - 0.1 11.5 0.4 31 3.4 0.1 3.6 1 1 2 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein ATPase_2 PF01637.18 ORY00158.1 - 0.13 12.2 0.0 0.26 11.1 0.0 1.5 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea NTPase_1 PF03266.15 ORY00158.1 - 0.19 11.6 0.0 0.42 10.5 0.0 1.5 1 0 0 1 1 1 0 NTPase Ploopntkinase3 PF18751.1 ORY00158.1 - 0.21 11.5 0.2 0.59 10.0 0.0 1.9 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 Cupin_1 PF00190.22 ORY00159.1 - 5.7e-37 126.6 0.0 2.4e-17 62.9 0.0 2.1 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 ORY00159.1 - 2.8e-26 91.0 0.5 3.9e-12 45.7 0.0 2.3 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.19 ORY00159.1 - 1.3e-09 38.1 0.6 0.00013 21.9 0.1 2.3 2 0 0 2 2 2 2 AraC-like ligand binding domain CENP-C_C PF11699.8 ORY00159.1 - 2.5e-05 24.4 0.0 0.012 15.8 0.0 2.4 2 0 0 2 2 2 2 Mif2/CENP-C like Cupin_3 PF05899.12 ORY00159.1 - 3.6e-05 23.4 0.0 0.14 11.9 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF861) 3-HAO PF06052.12 ORY00159.1 - 0.00012 21.8 0.0 0.29 10.7 0.0 2.2 2 0 0 2 2 2 2 3-hydroxyanthranilic acid dioxygenase Ectoine_synth PF06339.12 ORY00159.1 - 0.00015 21.9 0.1 0.088 13.0 0.0 2.2 2 0 0 2 2 2 2 Ectoine synthase ARD PF03079.14 ORY00159.1 - 0.0042 17.3 0.0 0.25 11.5 0.0 2.2 2 0 0 2 2 2 1 ARD/ARD' family Cupin_4 PF08007.12 ORY00159.1 - 0.007 15.9 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_6 PF12852.7 ORY00159.1 - 0.0071 16.1 0.0 0.049 13.3 0.0 2.0 2 0 0 2 2 2 1 Cupin SLAC1 PF03595.17 ORY00160.1 - 5.6e-25 88.3 22.2 3.9e-14 52.7 3.4 2.0 1 1 0 2 2 2 2 Voltage-dependent anion channel MAT1-1-2 PF17043.5 ORY00160.1 - 0.062 13.2 0.0 2.8 7.8 0.0 2.2 2 0 0 2 2 2 0 Mating type protein 1-1-2 of unknown function YlaC PF10777.9 ORY00160.1 - 9.6 6.0 6.6 12 5.8 0.4 2.9 3 0 0 3 3 3 0 Inner membrane protein YlaC Thiolase_C PF02803.18 ORY00161.1 - 1.5e-12 47.2 0.9 2.9e-11 43.1 0.2 2.8 2 1 1 3 3 3 1 Thiolase, C-terminal domain Thiolase_N PF00108.23 ORY00161.1 - 3.4e-12 46.3 0.1 7.9e-10 38.5 0.1 3.0 2 1 0 2 2 2 1 Thiolase, N-terminal domain ACP_syn_III PF08545.10 ORY00161.1 - 6.3e-07 29.2 0.0 0.0001 22.1 0.1 2.6 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.26 ORY00161.1 - 0.00036 20.2 0.1 0.0021 17.7 0.0 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 ORY00161.1 - 0.012 15.7 0.0 0.22 11.5 0.0 2.5 2 0 0 2 2 2 0 Beta-ketoacyl synthase, C-terminal domain DUF4811 PF16069.5 ORY00161.1 - 0.039 13.8 0.2 0.063 13.2 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4811) SpoVAD PF07451.11 ORY00161.1 - 0.078 11.7 0.1 0.84 8.3 0.1 2.1 2 0 0 2 2 2 0 Stage V sporulation protein AD (SpoVAD) ABC2_membrane PF01061.24 ORY00162.1 - 3e-27 95.4 28.1 4.7e-27 94.8 28.1 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 ORY00162.1 - 5.4e-26 91.7 0.1 1e-25 90.9 0.1 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ORY00162.1 - 1.8e-05 24.7 0.0 0.11 12.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 ORY00162.1 - 4.9e-05 23.3 0.4 0.00014 21.8 0.1 1.8 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 ORY00162.1 - 0.0002 21.0 0.5 0.00039 20.1 0.0 1.6 2 0 0 2 2 1 1 AAA domain AAA_22 PF13401.6 ORY00162.1 - 0.00048 20.4 0.0 0.003 17.9 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ORY00162.1 - 0.00056 20.3 0.1 0.001 19.5 0.1 1.4 1 0 0 1 1 1 1 AAA ATPase domain T2SSE PF00437.20 ORY00162.1 - 0.0019 17.3 0.4 0.0034 16.5 0.1 1.5 2 0 0 2 2 2 1 Type II/IV secretion system protein SMC_N PF02463.19 ORY00162.1 - 0.003 17.0 0.0 0.036 13.5 0.0 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_14 PF13173.6 ORY00162.1 - 0.0048 16.9 0.0 0.013 15.6 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_29 PF13555.6 ORY00162.1 - 0.0059 16.3 0.2 0.018 14.8 0.2 1.8 2 0 0 2 2 1 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 ORY00162.1 - 0.0087 16.1 0.1 0.018 15.1 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA PF00004.29 ORY00162.1 - 0.016 15.6 0.2 0.24 11.8 0.0 2.6 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) SRPRB PF09439.10 ORY00162.1 - 0.021 14.3 0.1 0.039 13.4 0.1 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_28 PF13521.6 ORY00162.1 - 0.021 15.0 0.1 0.041 14.1 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 ORY00162.1 - 0.023 15.3 0.0 0.042 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 ORY00162.1 - 0.025 14.6 0.0 0.066 13.2 0.0 1.7 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 ORY00162.1 - 0.029 13.9 0.0 0.056 13.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 ORY00162.1 - 0.035 14.3 0.0 0.056 13.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 ORY00162.1 - 0.04 13.8 0.0 0.076 12.9 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_13 PF13166.6 ORY00162.1 - 0.041 12.5 0.5 0.75 8.4 0.1 2.1 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 ORY00162.1 - 0.042 14.2 0.1 0.25 11.8 0.0 2.1 2 0 0 2 2 2 0 RNA helicase IstB_IS21 PF01695.17 ORY00162.1 - 0.055 13.2 0.2 0.24 11.1 0.0 2.1 3 0 0 3 3 2 0 IstB-like ATP binding protein AAA_30 PF13604.6 ORY00162.1 - 0.059 13.1 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 ORY00162.1 - 0.059 13.1 0.1 0.21 11.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 ORY00162.1 - 0.077 12.6 0.0 0.077 12.6 0.0 1.5 2 0 0 2 2 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.6 ORY00162.1 - 0.1 13.0 0.1 0.16 12.3 0.1 1.3 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 ORY00162.1 - 0.11 12.4 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain Septin PF00735.18 ORY00162.1 - 0.14 11.4 0.0 0.27 10.5 0.0 1.4 1 0 0 1 1 1 0 Septin ATPase_2 PF01637.18 ORY00162.1 - 0.16 11.9 0.0 0.26 11.2 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea LUC7 PF03194.15 ORY00163.1 - 4.5e-71 239.5 3.8 5.5e-71 239.2 3.8 1.0 1 0 0 1 1 1 1 LUC7 N_terminus LLC1 PF14945.6 ORY00163.1 - 0.098 13.2 0.3 0.18 12.4 0.3 1.4 1 0 0 1 1 1 0 Normal lung function maintenance, Low in Lung Cancer 1 protein Laminin_II PF06009.12 ORY00163.1 - 0.11 12.6 1.0 0.18 11.8 1.0 1.3 1 0 0 1 1 1 0 Laminin Domain II MCPsignal PF00015.21 ORY00163.1 - 0.13 12.1 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain V_ATPase_I PF01496.19 ORY00163.1 - 0.33 8.8 1.1 0.43 8.4 1.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF496 PF04363.12 ORY00163.1 - 1.2 9.2 4.5 2.3 8.3 0.6 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF496) Gpi16 PF04113.14 ORY00164.1 - 1.3e-239 796.3 0.0 1.6e-239 796.1 0.0 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component Fe-ADH PF00465.19 ORY00165.1 - 5.6e-103 344.5 0.0 7.1e-103 344.2 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 ORY00165.1 - 4e-15 56.2 0.0 1.4e-11 44.5 0.0 2.3 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Peripla_BP_6 PF13458.6 ORY00165.1 - 0.038 13.7 0.0 0.073 12.7 0.0 1.4 1 0 0 1 1 1 0 Periplasmic binding protein Zds_C PF08632.10 ORY00166.1 - 8.3e-29 99.1 1.2 1.5e-28 98.3 1.2 1.5 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term EF_assoc_2 PF08356.12 ORY00167.1 - 1.1e-33 115.1 0.0 2.3e-33 114.0 0.0 1.6 1 0 0 1 1 1 1 EF hand associated EF_assoc_1 PF08355.12 ORY00167.1 - 7.3e-29 99.2 0.2 1.2e-28 98.4 0.2 1.4 1 0 0 1 1 1 1 EF hand associated Ras PF00071.22 ORY00167.1 - 4.6e-26 91.4 0.0 1.5e-14 53.9 0.0 2.2 2 0 0 2 2 2 2 Ras family Roc PF08477.13 ORY00167.1 - 3.9e-13 49.7 0.0 1.1e-07 32.1 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 ORY00167.1 - 6.7e-09 35.8 0.0 1.8e-05 24.8 0.0 2.9 2 1 0 2 2 2 2 50S ribosome-binding GTPase EF-hand_6 PF13405.6 ORY00167.1 - 9.7e-07 28.2 4.3 0.018 14.9 0.2 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 ORY00167.1 - 2.3e-06 26.7 1.2 0.0099 15.4 0.3 2.8 2 0 0 2 2 2 2 EF hand AAA_16 PF13191.6 ORY00167.1 - 1.9e-05 25.1 0.1 0.028 14.8 0.0 2.8 3 0 0 3 3 3 1 AAA ATPase domain RsgA_GTPase PF03193.16 ORY00167.1 - 2.1e-05 24.5 0.0 0.35 10.8 0.0 3.3 3 0 0 3 3 3 1 RsgA GTPase AAA_22 PF13401.6 ORY00167.1 - 9.9e-05 22.6 0.0 0.16 12.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 ORY00167.1 - 0.00016 21.4 0.0 0.21 11.4 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain EF-hand_7 PF13499.6 ORY00167.1 - 0.00036 20.9 0.6 0.51 10.8 0.2 2.7 2 0 0 2 2 2 1 EF-hand domain pair RNA_helicase PF00910.22 ORY00167.1 - 0.00086 19.7 0.0 0.33 11.4 0.0 2.6 2 0 0 2 2 2 1 RNA helicase ABC_tran PF00005.27 ORY00167.1 - 0.001 19.6 0.0 0.83 10.2 0.0 2.4 2 0 0 2 2 2 1 ABC transporter Septin PF00735.18 ORY00167.1 - 0.004 16.5 0.0 0.89 8.8 0.0 2.2 2 0 0 2 2 2 1 Septin Dynamin_N PF00350.23 ORY00167.1 - 0.0079 16.3 0.3 5.3 7.1 0.1 2.4 2 0 0 2 2 2 1 Dynamin family EF-hand_5 PF13202.6 ORY00167.1 - 0.008 15.6 3.5 0.16 11.6 1.7 2.8 2 0 0 2 2 2 1 EF hand AAA_24 PF13479.6 ORY00167.1 - 0.011 15.4 0.1 0.91 9.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 ORY00167.1 - 0.014 14.9 0.0 2.3 7.7 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_28 PF13521.6 ORY00167.1 - 0.014 15.7 0.0 2.4 8.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 ORY00167.1 - 0.015 15.3 0.1 4.3 7.2 0.0 2.9 3 0 0 3 3 2 0 NACHT domain DUF815 PF05673.13 ORY00167.1 - 0.076 12.2 0.0 7 5.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_18 PF13238.6 ORY00167.1 - 0.077 13.5 5.5 1.2 9.6 0.2 3.7 3 2 1 4 4 3 0 AAA domain AAA_23 PF13476.6 ORY00167.1 - 0.079 13.5 0.1 9.4 6.7 0.1 2.4 2 0 0 2 2 2 0 AAA domain AIG1 PF04548.16 ORY00167.1 - 0.086 12.2 0.1 0.8 9.0 0.0 2.1 2 0 0 2 2 2 0 AIG1 family Ploopntkinase3 PF18751.1 ORY00167.1 - 0.09 12.7 0.0 2 8.3 0.0 2.2 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 EF-hand_10 PF14788.6 ORY00167.1 - 0.1 12.5 0.6 0.82 9.6 0.1 2.3 2 0 0 2 2 2 0 EF hand AAA_33 PF13671.6 ORY00167.1 - 0.14 12.3 0.4 8.5 6.5 0.0 2.9 3 1 0 4 4 2 0 AAA domain Viral_helicase1 PF01443.18 ORY00167.1 - 0.15 11.7 0.2 7.6 6.2 0.0 2.8 2 1 1 3 3 3 0 Viral (Superfamily 1) RNA helicase FtsK_SpoIIIE PF01580.18 ORY00167.1 - 0.17 11.2 0.0 2.9 7.2 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family ATP_bind_1 PF03029.17 ORY00167.1 - 0.2 11.4 0.7 37 4.0 0.0 3.1 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein WD40 PF00400.32 ORY00168.1 - 4.9e-13 49.3 13.3 0.00013 22.6 0.1 6.0 5 1 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY00168.1 - 8.8e-10 38.8 0.0 0.0063 16.8 0.0 3.8 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.12 ORY00168.1 - 0.00046 18.3 0.0 0.0011 17.1 0.0 1.5 1 1 1 2 2 2 1 IKI3 family eIF2A PF08662.11 ORY00168.1 - 0.00055 19.9 0.1 0.0066 16.4 0.0 2.1 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 ORY00168.1 - 0.0083 16.0 0.0 2.5 8.1 0.0 2.8 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat Utp8 PF10395.9 ORY00168.1 - 0.016 13.8 0.0 0.024 13.2 0.0 1.2 1 0 0 1 1 1 0 Utp8 family Cytochrom_D1 PF02239.16 ORY00168.1 - 0.03 12.9 0.0 0.12 10.9 0.0 1.7 1 1 0 1 1 1 0 Cytochrome D1 heme domain Arrestin_N PF00339.29 ORY00171.1 - 1.1e-12 48.3 0.0 2.6e-12 47.0 0.0 1.5 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 ORY00171.1 - 7.2e-10 39.4 0.1 2.8e-09 37.5 0.0 1.9 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain UBA PF00627.31 ORY00173.1 - 9e-06 25.5 0.1 0.00011 22.0 0.0 2.3 2 0 0 2 2 2 1 UBA/TS-N domain Glyco_hydro_18 PF00704.28 ORY00173.1 - 1.1e-05 25.3 0.0 0.047 13.4 0.0 2.6 3 0 0 3 3 3 2 Glycosyl hydrolases family 18 HET PF06985.11 ORY00174.1 - 7.6e-34 117.2 0.0 1.3e-33 116.4 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Pkinase PF00069.25 ORY00175.1 - 1.2e-72 244.5 0.0 1.5e-72 244.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY00175.1 - 5.6e-33 114.3 0.0 7e-33 114.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY00175.1 - 9.9e-05 21.8 0.1 0.00055 19.3 0.0 2.0 2 1 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 ORY00175.1 - 0.0011 18.0 0.1 0.058 12.3 0.0 2.1 2 0 0 2 2 2 2 Haspin like kinase domain APH PF01636.23 ORY00175.1 - 0.0094 15.9 0.1 0.021 14.7 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 ORY00175.1 - 0.074 12.1 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 2OG-FeII_Oxy_2 PF13532.6 ORY00176.1 - 8.8e-32 110.9 0.0 3.3e-31 109.0 0.0 1.9 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PAF-AH_p_II PF03403.13 ORY00177.1 - 2.3e-09 36.2 0.0 1.9e-06 26.7 0.0 2.3 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Hydrolase_4 PF12146.8 ORY00177.1 - 2.5e-07 30.2 0.0 0.01 15.1 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 ORY00177.1 - 9.3e-06 25.5 0.0 0.14 12.0 0.0 2.3 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_6 PF12697.7 ORY00177.1 - 5.3e-05 23.9 2.0 0.00011 22.9 2.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ORY00177.1 - 9.8e-05 22.1 0.7 0.00099 18.8 0.7 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 ORY00177.1 - 0.15 10.9 0.1 0.28 10.1 0.1 1.4 1 1 0 1 1 1 0 Chlorophyllase enzyme IZUMO PF15005.6 ORY00178.1 - 0.16 12.4 0.1 0.48 10.9 0.0 1.8 1 1 0 1 1 1 0 Izumo sperm-egg fusion, Ig domain-associated DUF572 PF04502.13 ORY00179.1 - 2.1e-64 218.2 0.0 2.6e-64 218.0 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) G-alpha PF00503.20 ORY00180.1 - 1.1e-62 212.3 0.4 8.9e-62 209.3 0.4 2.2 1 1 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 ORY00180.1 - 3.6e-05 23.3 0.5 0.0035 16.8 0.0 2.7 3 0 0 3 3 3 2 ADP-ribosylation factor family Helo_like_N PF17111.5 ORY00180.1 - 0.00026 20.4 3.9 0.00055 19.4 3.9 1.6 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins MGC-24 PF05283.11 ORY00182.1 - 0.0033 17.9 1.3 0.0052 17.2 1.3 1.3 1 0 0 1 1 1 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin EphA2_TM PF14575.6 ORY00182.1 - 0.0062 17.4 0.1 0.013 16.4 0.1 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Mid2 PF04478.12 ORY00182.1 - 0.0096 15.8 0.1 0.016 15.0 0.1 1.3 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Syndecan PF01034.20 ORY00182.1 - 0.05 13.5 1.4 0.065 13.2 0.1 1.8 2 0 0 2 2 2 0 Syndecan domain Herpes_gE PF02480.16 ORY00182.1 - 0.085 11.6 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Protocadherin PF08374.11 ORY00182.1 - 0.1 12.6 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Protocadherin TMEM154 PF15102.6 ORY00182.1 - 0.11 12.4 0.0 0.25 11.3 0.0 1.7 1 1 0 1 1 1 0 TMEM154 protein family Helicase_C PF00271.31 ORY00223.1 - 4.9e-20 71.9 0.1 1.8e-19 70.1 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY00223.1 - 7.3e-20 71.7 0.0 1.5e-19 70.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 ORY00223.1 - 8.6e-17 61.5 0.0 2.2e-16 60.1 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 ORY00223.1 - 0.0067 16.1 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 SWI2/SNF2 ATPase ERCC3_RAD25_C PF16203.5 ORY00223.1 - 0.048 12.9 0.0 0.088 12.0 0.0 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase PLDc_N PF13396.6 ORY00225.1 - 5.6e-12 45.4 2.8 5.6e-12 45.4 2.8 1.6 2 0 0 2 2 2 1 Phospholipase_D-nuclease N-terminal DUF2207 PF09972.9 ORY00225.1 - 0.029 13.1 1.0 0.028 13.2 1.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Phage_holin_3_6 PF07332.11 ORY00225.1 - 0.073 13.1 0.2 0.11 12.6 0.1 1.4 1 1 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DUF1673 PF07895.11 ORY00225.1 - 0.17 11.6 1.8 0.26 11.0 1.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1673) DUF608 PF04685.13 ORY00226.1 - 0.18 10.9 0.0 0.21 10.8 0.0 1.1 1 0 0 1 1 1 0 Glycosyl-hydrolase family 116, catalytic region zf-HC5HC2H_2 PF13832.6 ORY00228.1 - 2.2e-19 69.7 25.9 4.9e-19 68.5 1.3 3.9 3 1 0 3 3 3 2 PHD-zinc-finger like domain BAH PF01426.18 ORY00228.1 - 1.6e-14 53.8 0.1 3.6e-14 52.7 0.1 1.5 1 0 0 1 1 1 1 BAH domain zf-HC5HC2H PF13771.6 ORY00228.1 - 4e-14 52.6 1.7 4e-14 52.6 1.7 4.6 4 0 0 4 4 4 2 PHD-like zinc-binding domain PHD PF00628.29 ORY00228.1 - 5.8e-10 38.9 56.7 6.4e-06 26.0 8.4 6.4 7 0 0 7 7 7 3 PHD-finger PHD_2 PF13831.6 ORY00228.1 - 4.8e-07 29.2 5.9 4.8e-07 29.2 5.9 5.1 6 0 0 6 6 6 1 PHD-finger C1_2 PF03107.16 ORY00228.1 - 0.016 15.5 0.3 0.016 15.5 0.3 6.1 6 0 0 6 6 6 0 C1 domain RCR PF12273.8 ORY00229.1 - 7.6e-09 36.3 17.0 4e-08 33.9 17.0 1.9 1 1 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red COX1 PF00115.20 ORY00229.1 - 0.069 12.0 0.4 0.087 11.7 0.4 1.1 1 0 0 1 1 1 0 Cytochrome C and Quinol oxidase polypeptide I tRNA-synt_2c PF01411.19 ORY00231.1 - 1.4e-218 726.9 0.0 1.9e-218 726.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 ORY00231.1 - 4.9e-18 65.0 0.4 1.2e-17 63.8 0.4 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 ORY00231.1 - 1.7e-07 31.7 4.2 1.7e-07 31.7 4.2 2.3 2 0 0 2 2 2 1 DHHA1 domain adh_short_C2 PF13561.6 ORY00232.1 - 2e-30 106.1 0.0 5.5e-30 104.7 0.0 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY00232.1 - 1.8e-23 83.0 0.0 3e-23 82.3 0.0 1.3 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORY00232.1 - 6.8e-05 22.8 0.0 0.0004 20.3 0.0 1.9 2 0 0 2 2 2 1 KR domain dCMP_cyt_deam_1 PF00383.23 ORY00233.1 - 1.7e-09 37.5 0.6 1.3e-08 34.6 0.6 2.0 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 ORY00233.1 - 0.00064 19.9 0.8 0.31 11.2 0.3 2.9 2 1 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.6 ORY00233.1 - 0.0024 17.5 3.2 0.089 12.4 0.1 2.1 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases HSCB_C PF07743.13 ORY00234.1 - 4.2e-21 75.2 9.1 1.5e-20 73.4 7.4 2.1 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 ORY00234.1 - 8e-06 25.9 0.4 1.7e-05 24.8 0.4 1.5 1 0 0 1 1 1 1 DnaJ domain DUF1283 PF06932.11 ORY00234.1 - 0.12 12.6 0.7 0.22 11.7 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1283) DUF1117 PF06547.12 ORY00234.1 - 0.57 10.7 2.5 1.6 9.3 1.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1117) Pkinase PF00069.25 ORY00235.1 - 4.9e-68 229.4 0.0 7.2e-68 228.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY00235.1 - 1.5e-37 129.3 0.0 2.7e-37 128.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase PRKCSH PF07915.13 ORY00235.1 - 8.8e-18 65.1 0.0 8.8e-18 65.1 0.0 2.3 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein FHA PF00498.26 ORY00235.1 - 1.6e-08 34.8 0.4 1.1e-07 32.1 0.2 2.3 2 0 0 2 2 2 1 FHA domain Kdo PF06293.14 ORY00235.1 - 0.00055 19.4 0.1 0.001 18.4 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 ORY00235.1 - 0.0014 18.0 0.0 0.0025 17.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Yop-YscD_cpl PF16697.5 ORY00235.1 - 0.038 14.3 0.0 0.13 12.6 0.0 1.9 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain Pkinase_fungal PF17667.1 ORY00235.1 - 0.06 12.1 0.0 0.06 12.1 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase RIO1 PF01163.22 ORY00235.1 - 0.17 11.4 0.3 0.37 10.4 0.3 1.4 1 0 0 1 1 1 0 RIO1 family ABC_membrane PF00664.23 ORY00236.1 - 4.8e-96 321.6 32.2 1.5e-54 185.5 7.8 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 ORY00236.1 - 3.1e-62 209.1 0.0 1.7e-32 112.8 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 ORY00236.1 - 1.6e-14 53.9 0.2 0.0011 18.5 0.0 4.3 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 ORY00236.1 - 1e-09 38.8 0.5 0.0043 17.3 0.0 3.5 3 1 0 3 3 2 2 AAA domain ABC_ATPase PF09818.9 ORY00236.1 - 4e-08 32.5 0.4 0.018 13.8 0.1 3.3 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_21 PF13304.6 ORY00236.1 - 6e-08 32.9 0.3 1.1 9.0 0.0 4.3 2 2 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 ORY00236.1 - 7.6e-08 32.0 0.4 0.0015 18.2 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 ORY00236.1 - 1.2e-07 32.2 1.3 0.0027 18.1 0.0 3.1 2 1 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 ORY00236.1 - 1.6e-06 28.1 0.1 0.091 12.7 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 ORY00236.1 - 5.4e-05 23.8 0.2 0.069 13.6 0.1 2.4 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 ORY00236.1 - 5.5e-05 23.4 0.3 0.1 12.7 0.0 2.8 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_30 PF13604.6 ORY00236.1 - 0.00013 21.8 2.9 0.32 10.7 0.0 3.9 5 0 0 5 5 5 2 AAA domain AAA_15 PF13175.6 ORY00236.1 - 0.00014 21.7 0.0 0.65 9.6 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_5 PF07728.14 ORY00236.1 - 0.00019 21.5 0.0 0.12 12.4 0.0 3.4 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) SbcCD_C PF13558.6 ORY00236.1 - 0.0003 21.0 2.3 1.8 8.9 0.4 4.1 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.6 ORY00236.1 - 0.00031 21.3 0.4 0.39 11.3 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 ORY00236.1 - 0.00035 20.7 0.0 0.77 9.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 ORY00236.1 - 0.00052 20.4 0.3 8 6.9 0.0 4.1 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 ORY00236.1 - 0.00061 19.8 0.1 0.062 13.2 0.0 2.7 3 0 0 3 3 2 1 Rad17 P-loop domain AAA_7 PF12775.7 ORY00236.1 - 0.0013 18.2 0.1 0.12 11.9 0.0 2.7 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_25 PF13481.6 ORY00236.1 - 0.0024 17.5 0.0 2.2 7.8 0.0 2.9 3 0 0 3 3 3 1 AAA domain DUF3987 PF13148.6 ORY00236.1 - 0.0031 16.6 0.0 0.16 11.0 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3987) SRP54 PF00448.22 ORY00236.1 - 0.0044 16.7 0.0 0.7 9.5 0.0 2.5 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain RNA_helicase PF00910.22 ORY00236.1 - 0.0058 17.0 0.0 1.2 9.6 0.0 2.6 2 0 0 2 2 2 1 RNA helicase TniB PF05621.11 ORY00236.1 - 0.0083 15.6 0.0 8.6 5.7 0.0 3.4 3 0 0 3 3 3 0 Bacterial TniB protein MMR_HSR1 PF01926.23 ORY00236.1 - 0.012 15.7 0.0 5.3 7.2 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase Zeta_toxin PF06414.12 ORY00236.1 - 0.023 14.0 0.0 3 7.1 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin dNK PF01712.19 ORY00236.1 - 0.025 14.4 0.0 1.3 8.9 0.0 2.3 2 0 0 2 2 2 0 Deoxynucleoside kinase AAA_24 PF13479.6 ORY00236.1 - 0.025 14.3 0.3 1.9 8.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 ORY00236.1 - 0.027 14.7 0.4 1.4 9.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain PRK PF00485.18 ORY00236.1 - 0.028 14.2 0.1 3.8 7.2 0.0 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family ATP_bind_1 PF03029.17 ORY00236.1 - 0.03 14.1 0.5 4.5 7.0 0.1 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_10 PF12846.7 ORY00236.1 - 0.04 12.9 0.0 4.2 6.2 0.0 2.5 2 0 0 2 2 2 0 AAA-like domain DUF1400 PF07176.11 ORY00236.1 - 0.043 14.1 0.1 0.33 11.2 0.0 2.5 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1400) AAA_17 PF13207.6 ORY00236.1 - 0.12 12.8 0.2 3.2 8.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.20 ORY00236.1 - 0.13 11.4 0.0 15 4.7 0.0 2.3 2 0 0 2 2 2 0 G-protein alpha subunit ATP-synt_ab PF00006.25 ORY00236.1 - 0.15 11.7 0.5 1.7 8.2 0.0 2.6 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain ATPase PF06745.13 ORY00236.1 - 0.3 10.4 3.3 0.83 8.9 0.0 2.6 3 0 0 3 3 2 0 KaiC Cornifin PF02389.15 ORY00237.1 - 0.0025 18.0 0.1 0.0039 17.4 0.1 1.3 1 1 0 1 1 1 1 Cornifin (SPRR) family PTP_tm PF18861.1 ORY00238.1 - 0.054 13.5 0.0 0.089 12.8 0.0 1.4 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J DUF4690 PF15756.5 ORY00238.1 - 0.18 12.4 2.4 0.19 12.3 0.5 2.0 1 1 1 2 2 2 0 Small Novel Rich in Cartilage Kelch_1 PF01344.25 ORY00239.1 - 3.8e-30 103.2 18.4 1.6e-08 33.9 0.0 6.2 7 1 0 7 7 7 5 Kelch motif Kelch_6 PF13964.6 ORY00239.1 - 3.5e-29 100.1 9.2 1.1e-08 35.0 0.0 6.8 1 1 6 7 7 7 6 Kelch motif Kelch_2 PF07646.15 ORY00239.1 - 2.7e-19 68.3 2.0 8.9e-05 22.3 0.0 5.8 6 0 0 6 6 6 4 Kelch motif Kelch_4 PF13418.6 ORY00239.1 - 2.9e-18 65.6 14.2 8.5e-06 25.7 0.0 6.3 5 1 1 6 6 6 4 Galactose oxidase, central domain Kelch_3 PF13415.6 ORY00239.1 - 4.4e-16 58.7 4.6 4.8e-07 29.9 0.0 5.7 6 1 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.6 ORY00239.1 - 1.9e-13 50.1 0.4 0.0005 20.0 0.0 5.5 5 0 0 5 5 5 3 Kelch motif Bromodomain PF00439.25 ORY00242.1 - 2.1e-36 123.8 0.1 2.7e-18 65.8 0.1 2.4 2 0 0 2 2 2 2 Bromodomain Pkinase PF00069.25 ORY00243.1 - 1.2e-67 228.1 0.0 1.5e-67 227.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY00243.1 - 2.4e-36 125.3 0.0 3.3e-36 124.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY00243.1 - 2.6e-07 30.3 0.0 3.9e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like TetR_C_27 PF17935.1 ORY00243.1 - 0.0057 16.7 0.0 0.015 15.4 0.0 1.6 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain Kdo PF06293.14 ORY00243.1 - 0.0084 15.5 0.0 0.018 14.4 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RNA_pol_Rpo13 PF12136.8 ORY00243.1 - 0.02 14.8 0.5 0.043 13.7 0.5 1.5 1 0 0 1 1 1 0 RNA polymerase Rpo13 subunit HTH domain YrbL-PhoP_reg PF10707.9 ORY00243.1 - 0.034 13.7 0.0 0.16 11.5 0.0 2.1 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL DUF1381 PF07129.11 ORY00244.1 - 0.0032 17.3 0.1 0.0066 16.3 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1381) Glyco_hydro_72 PF03198.14 ORY00245.1 - 2.6e-09 36.8 0.0 2.9e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 Glucanosyltransferase DUF3905 PF13045.6 ORY00246.1 - 0.18 11.8 0.0 0.31 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3905) DUF4199 PF13858.6 ORY00247.1 - 0.0096 16.3 0.0 0.01 16.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4199) DUF4538 PF15061.6 ORY00247.1 - 0.025 14.3 0.1 0.04 13.7 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4538) UxaE PF16257.5 ORY00247.1 - 0.22 10.1 0.0 0.26 9.9 0.0 1.0 1 0 0 1 1 1 0 tagaturonate epimerase DUF1294 PF06961.13 ORY00248.1 - 4.2e-25 87.7 0.2 7.5e-25 86.9 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1294) DUF962 PF06127.11 ORY00248.1 - 0.12 12.4 1.1 0.15 12.1 1.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF962) zf-C2H2_4 PF13894.6 ORY00249.1 - 1.3e-07 31.9 6.4 0.0016 19.1 0.0 3.8 4 0 0 4 4 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 ORY00249.1 - 4.5e-05 23.3 2.5 0.00079 19.4 0.0 2.9 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2 PF00096.26 ORY00249.1 - 0.00018 21.8 5.6 0.067 13.7 0.0 3.7 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 ORY00249.1 - 0.0004 20.6 0.1 0.001 19.3 0.1 1.8 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ORY00249.1 - 0.0033 17.8 5.4 0.045 14.2 0.1 3.2 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-Di19 PF05605.12 ORY00249.1 - 0.023 15.0 3.5 1.5 9.1 1.5 2.5 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_9 PF16293.5 ORY00249.1 - 0.093 12.6 0.7 3.2 7.7 0.1 2.5 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) zf-C2H2_2 PF12756.7 ORY00249.1 - 0.11 12.8 3.1 13 6.1 0.1 2.9 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2HC_2 PF13913.6 ORY00249.1 - 0.99 9.4 0.0 0.99 9.4 0.0 3.3 3 0 0 3 3 2 0 zinc-finger of a C2HC-type zf-CRD PF17979.1 ORY00249.1 - 2.8 8.0 9.6 7.1 6.7 0.6 2.2 1 1 1 2 2 2 0 Cysteine rich domain with multizinc binding regions zf-H2C2_2 PF13465.6 ORY00249.1 - 9.1 6.9 10.6 13 6.5 0.1 3.3 3 0 0 3 3 3 0 Zinc-finger double domain Glyco_hydro_114 PF03537.13 ORY00250.1 - 1.8e-78 263.1 0.0 2.2e-78 262.7 0.0 1.1 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 CBM_1 PF00734.18 ORY00250.1 - 3.2e-07 30.2 19.3 2.1e-06 27.6 15.0 2.6 2 0 0 2 2 2 2 Fungal cellulose binding domain SOG2 PF10428.9 ORY00250.1 - 3.5 6.7 25.6 5 6.2 25.6 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein zf-RING_2 PF13639.6 ORY00251.1 - 3.8e-06 27.1 15.3 4.9e-06 26.8 6.7 2.9 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 ORY00251.1 - 6.4e-06 26.0 10.3 2.6e-05 24.0 8.8 2.6 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 ORY00251.1 - 4.5e-05 23.2 3.1 4.5e-05 23.2 3.1 2.2 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 ORY00251.1 - 0.0003 20.6 7.5 0.0003 20.6 7.5 2.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 ORY00251.1 - 0.00036 20.8 6.5 0.00036 20.8 6.5 2.6 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 ORY00251.1 - 0.0011 18.8 5.5 0.0011 18.8 5.5 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORY00251.1 - 0.005 16.8 4.8 0.005 16.8 4.8 2.6 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_4 PF14570.6 ORY00251.1 - 0.011 15.5 1.6 0.011 15.5 1.6 2.8 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.6 ORY00251.1 - 0.064 13.3 12.4 0.48 10.5 5.1 2.8 2 0 0 2 2 2 0 RING-type zinc-finger Cript PF10235.9 ORY00251.1 - 0.22 12.1 3.3 0.86 10.2 0.3 2.3 2 0 0 2 2 2 0 Microtubule-associated protein CRIPT zf-C3HC4_4 PF15227.6 ORY00251.1 - 0.39 10.9 13.0 0.3 11.3 5.5 2.9 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 ORY00251.1 - 0.85 9.7 10.6 1.9 8.6 4.8 2.5 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Agouti PF05039.12 ORY00251.1 - 6.2 7.6 9.9 1.6 9.5 0.8 2.8 3 0 0 3 3 3 0 Agouti protein F-box-like PF12937.7 ORY00252.1 - 1.1e-09 38.0 0.8 2.3e-09 37.0 0.8 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY00252.1 - 0.00046 20.0 0.5 0.00099 18.9 0.5 1.6 1 0 0 1 1 1 1 F-box domain Ribosomal_L21p PF00829.21 ORY00253.1 - 1.1e-07 32.1 0.0 2e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein Ribosomal_S8e PF01201.22 ORY00254.1 - 2.1e-46 157.5 1.9 3.3e-46 156.9 1.9 1.3 1 1 0 1 1 1 1 Ribosomal protein S8e PCI PF01399.27 ORY00255.1 - 7.1e-13 49.0 0.0 2.6e-12 47.2 0.0 2.0 2 0 0 2 2 2 1 PCI domain RPN7 PF10602.9 ORY00255.1 - 8.7e-05 22.3 0.2 0.00016 21.4 0.2 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 ComR_TPR PF18710.1 ORY00255.1 - 0.029 13.9 0.2 0.07 12.7 0.1 1.7 1 1 0 1 1 1 0 ComR tetratricopeptide TFIIF_beta_N PF17683.1 ORY00256.1 - 5e-23 82.3 0.0 1.1e-22 81.2 0.0 1.5 2 0 0 2 2 2 1 TFIIF, beta subunit N-terminus TFIIF_beta PF02270.15 ORY00256.1 - 4e-22 78.1 0.1 7.7e-22 77.2 0.1 1.5 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain Tau95 PF09734.9 ORY00256.1 - 3.6e-05 24.6 0.4 3.6e-05 24.6 0.4 1.8 2 1 0 2 2 2 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain DDE_Tnp_IS66_C PF13817.6 ORY00256.1 - 0.064 13.5 0.0 1.5 9.1 0.0 2.6 2 0 0 2 2 2 0 IS66 C-terminal element Rad17 PF03215.15 ORY00257.1 - 7.7e-28 97.7 0.0 1.8e-27 96.5 0.0 1.6 1 1 0 1 1 1 1 Rad17 P-loop domain T2SSE PF00437.20 ORY00257.1 - 0.0067 15.5 0.1 0.011 14.8 0.1 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_16 PF13191.6 ORY00257.1 - 0.017 15.5 0.0 0.039 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Zeta_toxin PF06414.12 ORY00257.1 - 0.024 13.9 0.0 0.05 12.9 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin TsaE PF02367.17 ORY00257.1 - 0.073 13.1 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 ORY00257.1 - 0.096 12.4 0.1 0.2 11.4 0.1 1.4 1 0 0 1 1 1 0 AAA domain TMF_DNA_bd PF12329.8 ORY00258.1 - 4.6e-05 23.3 14.4 4.6e-05 23.3 14.4 2.3 1 1 1 2 2 2 1 TATA element modulatory factor 1 DNA binding MAP70 PF07058.11 ORY00258.1 - 0.003 16.4 8.6 0.0045 15.8 8.6 1.2 1 0 0 1 1 1 1 Microtubule-associated protein 70 HMMR_N PF15905.5 ORY00258.1 - 0.038 13.5 18.6 0.061 12.8 18.6 1.2 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal DUF3584 PF12128.8 ORY00258.1 - 0.041 11.4 13.6 0.065 10.7 13.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) ACCA PF03255.14 ORY00258.1 - 3.8 7.4 7.1 2.4 8.1 4.9 1.7 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit TMF_TATA_bd PF12325.8 ORY00258.1 - 4.5 7.5 21.7 3.7 7.8 2.3 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding FAM76 PF16046.5 ORY00258.1 - 5.4 6.3 9.7 11 5.2 9.7 1.5 1 0 0 1 1 1 0 FAM76 protein Atg14 PF10186.9 ORY00258.1 - 9.9 5.1 16.7 17 4.4 16.7 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 adh_short PF00106.25 ORY00290.1 - 2.1e-26 92.6 0.0 8.4e-26 90.6 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY00290.1 - 3e-16 59.7 0.0 2.6e-15 56.6 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY00290.1 - 3.7e-07 30.2 0.1 1.7e-06 28.1 0.1 1.9 1 1 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 ORY00290.1 - 0.014 14.8 0.0 0.032 13.6 0.0 1.6 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Hpre_diP_synt_I PF07456.11 ORY00290.1 - 0.061 13.3 0.3 0.13 12.3 0.3 1.4 1 0 0 1 1 1 0 Heptaprenyl diphosphate synthase component I DUF2069 PF09842.9 ORY00290.1 - 0.11 12.8 1.0 1.8 8.8 0.0 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2069) HdeA PF06411.11 ORY00292.1 - 0.058 13.6 0.1 0.12 12.6 0.1 1.6 1 1 0 1 1 1 0 HdeA/HdeB family Cu_amine_oxid PF01179.20 ORY00293.1 - 2e-167 557.3 0.0 2.5e-167 557.0 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 ORY00293.1 - 0.00011 22.5 0.0 0.00024 21.4 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Fungal_trans PF04082.18 ORY00294.1 - 1.2e-13 50.7 0.0 1.9e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY00294.1 - 6.1e-08 32.6 6.5 9.7e-08 32.0 6.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Lipase_GDSL PF00657.22 ORY00295.1 - 2e-07 31.2 0.0 2.5e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 ORY00295.1 - 5.3e-07 30.2 2.5 8.6e-07 29.5 2.5 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Abhydrolase_3 PF07859.13 ORY00296.1 - 6.7e-37 127.4 0.0 9.6e-37 126.9 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 ORY00296.1 - 1.6e-10 40.4 0.0 2e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Aldo_ket_red PF00248.21 ORY00297.1 - 6e-68 229.2 0.0 6.9e-68 229.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family HTH_8 PF02954.19 ORY00297.1 - 2.5 7.9 5.6 3.3 7.6 0.0 3.3 4 0 0 4 4 4 0 Bacterial regulatory protein, Fis family Zn_clus PF00172.18 ORY00298.1 - 3.1e-06 27.2 12.3 5.8e-06 26.3 12.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 ORY00298.1 - 4.2e-06 25.8 0.1 6.7e-06 25.1 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Aldedh PF00171.22 ORY00299.1 - 1.6e-153 511.6 0.1 1.8e-153 511.4 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 ORY00299.1 - 5.5e-06 26.0 0.1 0.061 12.8 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) DUF2157 PF09925.9 ORY00305.1 - 0.3 10.9 4.6 0.44 10.3 4.6 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) TMEM72 PF16054.5 ORY00305.1 - 0.7 9.6 3.0 1.3 8.6 3.0 1.4 1 0 0 1 1 1 0 Transmembrane protein family 72 TRAPP PF04051.16 ORY00306.1 - 3e-41 140.6 0.0 3.8e-41 140.2 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Ldh_1_C PF02866.18 ORY00307.1 - 1.9e-46 158.1 0.0 2.8e-46 157.5 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 ORY00307.1 - 7.2e-44 149.3 0.0 9.9e-44 148.9 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 ORY00307.1 - 0.004 17.1 0.0 0.0089 15.9 0.0 1.7 2 0 0 2 2 2 1 NAD(P)H-binding 3Beta_HSD PF01073.19 ORY00307.1 - 0.0053 15.8 0.0 0.0083 15.2 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_hydro_4 PF02056.16 ORY00307.1 - 0.16 11.5 0.1 0.35 10.4 0.0 1.5 1 1 0 1 1 1 0 Family 4 glycosyl hydrolase CBFD_NFYB_HMF PF00808.23 ORY00308.1 - 3.4e-19 68.9 0.5 4.8e-19 68.4 0.5 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 ORY00308.1 - 1e-14 55.0 0.2 1.9e-14 54.2 0.2 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.10 ORY00308.1 - 0.058 13.7 0.0 0.1 12.9 0.0 1.4 1 0 0 1 1 1 0 CENP-S associating Centromere protein X Fcf2 PF08698.11 ORY00309.1 - 5.9e-37 126.0 0.4 5.9e-37 126.0 0.4 1.8 2 0 0 2 2 2 1 Fcf2 pre-rRNA processing PNP_UDP_1 PF01048.20 ORY00310.1 - 1.6e-54 184.6 1.3 3.3e-54 183.6 1.3 1.5 1 1 0 1 1 1 1 Phosphorylase superfamily Ribosomal_S10 PF00338.22 ORY00311.1 - 1.8e-24 85.8 0.1 5.1e-24 84.3 0.0 1.8 3 0 0 3 3 3 1 Ribosomal protein S10p/S20e DUF1688 PF07958.11 ORY00313.1 - 1e-172 574.6 0.0 1.1e-172 574.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) Q_salvage PF10343.9 ORY00313.1 - 0.0029 17.3 0.0 1.9 8.0 0.0 2.2 2 0 0 2 2 2 2 Potential Queuosine, Q, salvage protein family PepSY_2 PF13670.6 ORY00313.1 - 0.21 11.6 0.0 0.52 10.3 0.0 1.6 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain TraX PF05857.11 ORY00314.1 - 0.2 11.7 6.8 0.053 13.6 1.4 2.4 1 1 2 3 3 3 0 TraX protein Abhydrolase_9_N PF15420.6 ORY00314.1 - 4.4 7.2 18.1 2.9 7.8 5.6 3.0 2 1 1 3 3 3 0 Alpha/beta-hydrolase family N-terminus HET PF06985.11 ORY00316.1 - 3.4e-09 37.2 1.1 3.6e-06 27.4 0.0 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) DUF1996 PF09362.10 ORY00317.1 - 4.7e-75 252.6 6.3 6.1e-75 252.2 6.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Erf4 PF10256.9 ORY00319.1 - 0.0074 16.4 0.0 0.018 15.1 0.0 1.6 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family Spo12 PF05032.12 ORY00320.1 - 4.9e-14 51.9 1.8 4.9e-14 51.9 1.8 2.1 3 0 0 3 3 3 1 Spo12 family Herpes_BTRF1 PF04682.12 ORY00320.1 - 0.0029 17.0 0.8 0.0036 16.7 0.8 1.1 1 0 0 1 1 1 1 Herpesvirus BTRF1 protein conserved region UreF PF01730.16 ORY00321.1 - 2.2e-24 86.6 1.5 3.3e-24 85.9 1.5 1.3 1 0 0 1 1 1 1 UreF Sugarporin_N PF11471.8 ORY00321.1 - 0.0051 16.7 0.2 0.015 15.2 0.2 1.9 1 0 0 1 1 1 1 Maltoporin periplasmic N-terminal extension Pox_A_type_inc PF04508.12 ORY00321.1 - 0.11 12.4 1.2 0.64 10.0 0.2 2.3 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Lipase_GDSL_2 PF13472.6 ORY00322.1 - 2.1e-12 47.8 0.6 4.9e-12 46.6 0.6 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 ORY00322.1 - 1.1e-05 25.5 0.0 3.2e-05 24.0 0.0 1.8 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Gas_vesicle_C PF01304.17 ORY00322.1 - 0.0012 18.8 1.7 0.0026 17.7 1.7 1.5 1 0 0 1 1 1 1 Gas vesicles protein GVPc repeated domain Glyco_hydro_31 PF01055.26 ORY00323.1 - 1.3e-89 301.5 5.6 2.1e-89 300.8 5.6 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 DUF5110 PF17137.4 ORY00323.1 - 8.9e-06 25.9 0.0 6.5e-05 23.1 0.0 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF5110) DUF4968 PF16338.5 ORY00323.1 - 0.025 14.9 0.0 0.057 13.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4968) Gly_transf_sug PF04488.15 ORY00326.1 - 2.9e-15 56.7 0.0 6.5e-15 55.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Cu_amine_oxid PF01179.20 ORY00355.1 - 8.3e-102 341.1 2.1 1e-74 251.9 0.1 2.0 1 1 1 2 2 2 2 Copper amine oxidase, enzyme domain TauD PF02668.16 ORY00358.1 - 5.8e-23 82.0 0.0 7.7e-23 81.6 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Acetyltransf_1 PF00583.25 ORY00360.1 - 0.0028 17.9 0.0 0.0044 17.2 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ORY00360.1 - 0.0053 16.7 0.0 0.0096 15.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ORY00360.1 - 0.017 15.5 0.0 0.046 14.2 0.0 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain p450 PF00067.22 ORY00362.1 - 1.5e-49 169.0 0.0 1.7e-49 168.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF1996 PF09362.10 ORY00365.1 - 3.1e-66 223.7 0.5 4.6e-66 223.2 0.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) AAA_17 PF13207.6 ORY00366.1 - 2.5e-09 37.7 0.1 5.9e-09 36.5 0.0 1.7 2 0 0 2 2 2 1 AAA domain ADK PF00406.22 ORY00366.1 - 3.5e-08 33.7 0.0 1e-07 32.1 0.0 1.8 1 1 0 1 1 1 1 Adenylate kinase AAA_18 PF13238.6 ORY00366.1 - 0.00019 22.0 0.1 0.00057 20.4 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 ORY00366.1 - 0.00056 20.1 0.0 0.00095 19.3 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ORY00366.1 - 0.0062 16.9 0.0 0.0067 16.8 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 ORY00366.1 - 0.0065 16.7 0.0 0.01 16.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain Ploopntkinase3 PF18751.1 ORY00366.1 - 0.011 15.6 0.0 0.015 15.2 0.0 1.2 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 Cytidylate_kin PF02224.18 ORY00366.1 - 0.013 15.3 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase Zeta_toxin PF06414.12 ORY00366.1 - 0.016 14.5 0.0 0.026 13.8 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Rad17 PF03215.15 ORY00366.1 - 0.2 11.6 0.0 0.45 10.4 0.0 1.5 1 1 0 1 1 1 0 Rad17 P-loop domain Ifi-6-16 PF06140.13 ORY00367.1 - 9.6e-08 31.8 12.8 2.4e-06 27.3 7.6 2.2 2 0 0 2 2 2 2 Interferon-induced 6-16 family Ifi-6-16 PF06140.13 ORY00368.1 - 1.3e-11 44.2 11.1 2.4e-11 43.4 11.1 1.4 1 0 0 1 1 1 1 Interferon-induced 6-16 family DUF883 PF05957.13 ORY00368.1 - 0.018 15.6 0.0 0.047 14.3 0.0 1.7 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Promethin PF16015.5 ORY00368.1 - 1.8 8.5 8.6 26 4.8 8.6 2.1 1 1 0 1 1 1 0 Promethin Abhydrolase_2 PF02230.16 ORY00369.1 - 1.1e-60 205.1 0.0 1.3e-60 204.9 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 ORY00369.1 - 3.4e-06 26.7 1.6 0.00021 20.8 0.0 2.6 3 0 0 3 3 3 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 ORY00369.1 - 1.7e-05 24.2 1.0 0.0047 16.2 0.0 3.0 2 1 1 3 3 3 1 Serine aminopeptidase, S33 FSH1 PF03959.13 ORY00369.1 - 0.00011 21.9 0.0 0.0013 18.4 0.0 2.3 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 ORY00369.1 - 0.00074 20.2 0.0 0.00092 19.9 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 ORY00369.1 - 0.00086 18.9 0.0 0.0012 18.4 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 ORY00369.1 - 0.0033 17.3 0.1 0.53 10.1 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Esterase_phd PF10503.9 ORY00369.1 - 0.077 12.5 0.0 4.2 6.8 0.0 2.1 2 0 0 2 2 2 0 Esterase PHB depolymerase Cutinase PF01083.22 ORY00369.1 - 0.15 12.0 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 Cutinase HhH-GPD PF00730.25 ORY00370.1 - 0.00056 20.3 0.0 0.0012 19.3 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 ORY00370.1 - 0.0098 15.7 0.0 0.027 14.3 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif Glyco_hydro_76 PF03663.14 ORY00371.1 - 7.4e-38 131.0 15.7 9.5e-38 130.6 15.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 ORY00371.1 - 1.3e-09 37.6 4.4 2.7e-07 30.0 0.0 2.7 1 1 1 2 2 2 2 Glycosyl Hydrolase Family 88 C5-epim_C PF06662.13 ORY00371.1 - 0.00025 20.6 3.1 0.069 12.6 0.7 2.5 2 0 0 2 2 2 2 D-glucuronyl C5-epimerase C-terminus GlcNAc_2-epim PF07221.11 ORY00371.1 - 0.0033 16.7 0.8 0.7 9.1 0.0 3.2 3 1 0 3 3 3 2 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) Glyco_hydro_127 PF07944.12 ORY00371.1 - 0.02 13.4 0.1 0.91 7.9 0.0 2.3 2 0 0 2 2 2 0 Beta-L-arabinofuranosidase, GH127 HSP9_HSP12 PF04119.12 ORY00373.1 - 2.7e-25 88.5 3.6 3.2e-25 88.3 0.9 2.0 2 0 0 2 2 2 1 Heat shock protein 9/12 Grg1 PF11034.8 ORY00373.1 - 0.054 13.7 5.8 1.6 9.0 0.1 2.6 2 1 1 3 3 3 0 Glucose-repressible protein Grg1 Wbp11 PF09429.10 ORY00374.1 - 8.5e-22 77.4 15.9 8.5e-22 77.4 15.9 2.1 2 0 0 2 2 2 1 WW domain binding protein 11 Strep_SA_rep PF06696.11 ORY00374.1 - 0.0083 16.1 1.3 0.0083 16.1 1.3 2.2 2 0 0 2 2 2 1 Streptococcal surface antigen repeat CsgG PF03783.14 ORY00374.1 - 1.3 8.2 6.5 0.87 8.8 0.2 2.7 2 1 1 3 3 3 0 Curli production assembly/transport component CsgG 17kDa_Anti_2 PF16998.5 ORY00375.1 - 0.0027 17.6 0.2 0.0056 16.6 0.2 1.5 1 0 0 1 1 1 1 17 kDa outer membrane surface antigen AP3D1 PF06375.11 ORY00375.1 - 0.0034 17.6 2.2 0.0082 16.4 2.2 1.6 1 0 0 1 1 1 1 AP-3 complex subunit delta-1 BRF1 PF07741.13 ORY00375.1 - 2.3 8.6 10.7 0.2 12.0 5.3 2.0 2 0 0 2 2 2 0 Brf1-like TBP-binding domain AMP-binding PF00501.28 ORY00376.1 - 2.2e-75 253.9 0.0 2.7e-75 253.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORY00376.1 - 2.8e-13 50.7 0.1 9.9e-13 48.9 0.1 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Fasciclin PF02469.22 ORY00377.1 - 9.4e-47 158.4 0.0 1.4e-24 86.8 0.0 2.2 2 0 0 2 2 2 2 Fasciclin domain AMP_N PF05195.16 ORY00377.1 - 0.095 12.4 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 Aminopeptidase P, N-terminal domain DUF211 PF02680.14 ORY00377.1 - 0.14 12.3 0.0 0.52 10.5 0.0 1.9 1 0 0 1 1 1 0 Uncharacterized ArCR, COG1888 Phasin PF05597.11 ORY00377.1 - 0.18 11.8 0.1 0.36 10.8 0.1 1.4 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Pyridoxal_deC PF00282.19 ORY00378.1 - 1e-56 192.3 0.0 1.9e-56 191.4 0.0 1.5 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 ORY00378.1 - 4.4e-05 22.6 0.0 6.7e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V OKR_DC_1 PF01276.20 ORY00378.1 - 0.054 12.2 0.0 0.087 11.5 0.0 1.2 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain FAD_binding_7 PF03441.14 ORY00379.1 - 9.9e-44 149.2 0.1 2.1e-43 148.1 0.0 1.5 2 0 0 2 2 2 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 ORY00379.1 - 2e-12 47.4 0.0 1e-11 45.2 0.0 2.1 1 1 0 1 1 1 1 DNA photolyase DnaJ PF00226.31 ORY00380.1 - 3.9e-08 33.3 0.0 1.7e-07 31.3 0.0 2.1 1 1 0 1 1 1 1 DnaJ domain UreE_C PF05194.12 ORY00380.1 - 0.23 12.0 0.4 0.43 11.1 0.4 1.4 1 0 0 1 1 1 0 UreE urease accessory protein, C-terminal domain Trypsin_2 PF13365.6 ORY00381.1 - 2.3e-24 87.0 0.0 3.7e-24 86.3 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain Peptidase_S46 PF10459.9 ORY00381.1 - 0.084 11.5 0.0 0.12 11.0 0.0 1.1 1 0 0 1 1 1 0 Peptidase S46 Sgf11 PF08209.11 ORY00382.1 - 4.3e-15 55.0 1.7 4.6e-14 51.7 0.1 2.3 2 0 0 2 2 2 1 Sgf11 (transcriptional regulation protein) zf-RING_7 PF02591.15 ORY00382.1 - 0.2 11.9 1.1 21 5.4 0.0 2.8 3 0 0 3 3 3 0 C4-type zinc ribbon domain zf-ribbon_3 PF13248.6 ORY00382.1 - 0.47 9.9 2.7 12 5.5 0.3 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2HC_2 PF13913.6 ORY00382.1 - 0.72 9.8 8.6 0.25 11.3 1.2 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-Di19 PF05605.12 ORY00382.1 - 1.3 9.4 5.6 6.4 7.1 0.6 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Adaptin_binding PF10199.9 ORY00386.1 - 0.08 13.6 0.2 0.08 13.6 0.2 2.0 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 Metallophos PF00149.28 ORY00389.1 - 2.3e-10 41.3 0.2 3.4e-10 40.8 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 ORY00389.1 - 1.3e-08 35.2 0.0 0.00022 21.5 0.0 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain HLH PF00010.26 ORY00391.1 - 7.8e-14 51.4 0.1 1.5e-13 50.5 0.1 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Bromodomain PF00439.25 ORY00393.1 - 5.8e-08 32.7 0.0 4.2e-07 29.9 0.0 2.2 1 1 0 1 1 1 1 Bromodomain SKA1 PF07160.12 ORY00394.1 - 0.0033 17.3 0.7 0.0037 17.2 0.7 1.1 1 0 0 1 1 1 1 Spindle and kinetochore-associated protein 1 SlyX PF04102.12 ORY00394.1 - 0.0036 17.9 2.6 0.004 17.7 1.7 1.6 1 1 0 1 1 1 1 SlyX Sugarporin_N PF11471.8 ORY00394.1 - 0.0063 16.4 6.8 0.013 15.4 6.8 1.4 1 0 0 1 1 1 1 Maltoporin periplasmic N-terminal extension AAA_lid_9 PF17871.1 ORY00394.1 - 0.0094 15.9 2.2 0.011 15.6 1.6 1.4 1 1 0 1 1 1 1 AAA lid domain Csm1_N PF18504.1 ORY00394.1 - 0.033 14.5 0.9 0.033 14.5 0.9 1.6 2 0 0 2 2 2 0 Csm1 N-terminal domain Atg14 PF10186.9 ORY00394.1 - 0.044 12.9 1.8 0.053 12.6 1.8 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 RIC3 PF15361.6 ORY00394.1 - 0.094 13.1 0.5 0.094 13.1 0.5 1.7 2 0 0 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 zf-C3HC4 PF00097.25 ORY00440.1 - 2.2e-08 33.8 6.0 3.8e-08 33.1 6.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORY00440.1 - 5.2e-07 29.6 5.0 1.1e-06 28.5 5.0 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 ORY00440.1 - 1e-06 28.5 4.3 6.2e-06 26.0 1.4 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 ORY00440.1 - 2.7e-06 27.1 4.5 5.1e-06 26.3 4.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORY00440.1 - 7e-06 26.3 5.7 1.8e-05 25.0 5.7 1.7 1 1 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 ORY00440.1 - 1.5e-05 24.9 4.7 3.8e-05 23.6 4.8 1.6 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 ORY00440.1 - 2.1e-05 24.6 3.2 5e-05 23.4 3.3 1.7 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 ORY00440.1 - 0.051 13.9 4.4 0.15 12.4 4.4 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 ORY00440.1 - 0.13 12.2 11.0 1.9 8.4 10.0 2.7 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 UCH PF00443.29 ORY00441.1 - 7.3e-43 146.9 0.0 1.4e-42 145.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 ORY00441.1 - 4e-07 29.9 0.0 0.0057 16.3 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 ORY00441.1 - 0.13 11.7 0.0 19 4.6 0.0 3.0 3 0 0 3 3 3 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase DUF572 PF04502.13 ORY00441.1 - 0.29 10.7 6.4 0.56 9.8 6.4 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) Methyltransf_11 PF08241.12 ORY00442.1 - 0.21 12.3 0.0 0.52 11.0 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Mur_ligase_M PF08245.12 ORY00443.1 - 5e-06 26.6 0.0 7.2e-05 22.9 0.0 2.6 1 1 0 1 1 1 1 Mur ligase middle domain DUF2188 PF09954.9 ORY00443.1 - 0.14 12.4 0.1 11 6.3 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2188) Mur_ligase_C PF02875.21 ORY00443.1 - 0.15 12.4 0.0 0.44 10.8 0.0 1.9 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain zf-RING_2 PF13639.6 ORY00444.1 - 8.1e-05 22.9 4.6 0.0002 21.6 4.6 1.7 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 ORY00444.1 - 0.0022 17.8 0.4 0.0045 16.8 0.4 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 ORY00444.1 - 0.0072 16.6 4.7 0.017 15.4 4.7 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 ORY00444.1 - 0.012 15.6 2.9 0.032 14.3 2.9 1.8 1 1 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_2 PF13923.6 ORY00444.1 - 0.016 15.1 1.9 0.038 13.8 1.9 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 ORY00444.1 - 0.027 14.3 1.3 0.049 13.5 1.3 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORY00444.1 - 0.039 13.8 2.2 0.07 13.0 2.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C2H2_9 PF16293.5 ORY00444.1 - 0.063 13.1 0.0 0.53 10.2 0.0 2.2 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) zf-RING_11 PF17123.5 ORY00444.1 - 0.069 12.9 1.4 0.14 11.9 1.4 1.6 1 0 0 1 1 1 0 RING-like zinc finger Zn_ribbon_17 PF17120.5 ORY00444.1 - 0.38 10.4 2.5 0.74 9.5 2.5 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_2 PF13639.6 ORY00445.1 - 1.2e-09 38.4 9.3 2.6e-09 37.3 9.3 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 ORY00445.1 - 5.3e-05 22.9 8.2 0.00015 21.4 8.2 1.9 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 ORY00445.1 - 9.2e-05 22.7 8.6 0.00022 21.4 8.6 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 ORY00445.1 - 0.00092 19.2 3.1 0.0019 18.2 3.1 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 ORY00445.1 - 0.0016 18.3 7.5 0.0034 17.3 7.5 1.6 1 0 0 1 1 1 1 zinc-RING finger domain RINGv PF12906.7 ORY00445.1 - 0.0046 17.1 7.4 0.016 15.3 7.4 2.0 1 0 0 1 1 1 1 RING-variant domain zf-C3HC4 PF00097.25 ORY00445.1 - 0.0099 15.7 8.8 0.018 14.9 8.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 ORY00445.1 - 0.011 15.9 6.5 0.037 14.2 6.6 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_3 PF13920.6 ORY00445.1 - 0.012 15.5 5.8 0.022 14.6 5.8 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 ORY00445.1 - 0.013 15.3 9.9 0.021 14.7 8.9 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 ORY00445.1 - 0.043 13.5 3.8 0.095 12.3 3.8 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 ORY00445.1 - 0.043 13.7 6.0 0.082 12.8 6.0 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 PHD PF00628.29 ORY00445.1 - 0.097 12.6 6.4 0.19 11.6 6.4 1.5 1 0 0 1 1 1 0 PHD-finger KAP_NTPase PF07693.14 ORY00446.1 - 0.00023 20.5 0.0 0.00046 19.5 0.0 1.5 1 0 0 1 1 1 1 KAP family P-loop domain DUF4014 PF13198.6 ORY00446.1 - 0.061 13.7 0.0 0.14 12.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4014) HET PF06985.11 ORY00448.1 - 1.4e-11 45.0 7.1 9.1e-09 35.8 1.5 2.1 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) zf-C3HC4 PF00097.25 ORY00450.1 - 0.00029 20.6 1.9 0.00049 19.9 1.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 ORY00450.1 - 0.0018 18.1 1.6 0.0029 17.5 1.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORY00450.1 - 0.0021 18.1 0.4 0.0032 17.4 0.4 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 ORY00450.1 - 0.0083 16.4 1.3 0.014 15.7 1.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_4 PF14570.6 ORY00450.1 - 0.011 15.6 1.4 0.017 14.9 1.4 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_2 PF13923.6 ORY00450.1 - 0.026 14.4 2.0 0.048 13.5 2.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORY00450.1 - 0.064 13.2 1.2 0.12 12.4 1.2 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-MIZ PF02891.20 ORY00450.1 - 0.091 12.5 2.1 0.18 11.6 2.1 1.5 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger DUF4428 PF14471.6 ORY00450.1 - 0.11 12.4 0.4 0.17 11.8 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) ADP_ribosyl_GH PF03747.14 ORY00453.1 - 1.4e-57 195.7 0.3 1.6e-57 195.5 0.3 1.0 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase NIPSNAP PF07978.13 ORY00454.1 - 7.1e-42 141.8 0.4 2.3e-28 98.4 0.0 2.3 2 0 0 2 2 2 2 NIPSNAP CDP-OH_P_transf PF01066.21 ORY00455.1 - 8e-16 58.6 0.1 8e-16 58.6 0.1 3.1 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase DUF5313 PF17240.2 ORY00455.1 - 0.36 11.3 2.1 7.1 7.1 0.6 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5313) Stig1 PF04885.13 ORY00458.1 - 3.1e-06 27.7 3.0 3.1e-06 27.7 3.0 1.5 2 0 0 2 2 2 1 Stigma-specific protein, Stig1 Fer4_6 PF12837.7 ORY00458.1 - 9.2 6.5 10.8 8.7 6.6 1.3 3.5 4 0 0 4 4 4 0 4Fe-4S binding domain SIP1 PF04938.12 ORY00459.1 - 1.7e-16 60.6 0.0 6.1e-15 55.5 0.0 2.4 2 0 0 2 2 2 2 Survival motor neuron (SMN) interacting protein 1 (SIP1) OPT PF03169.15 ORY00460.1 - 5e-84 283.1 49.4 5.9e-84 282.8 49.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein SCO1-SenC PF02630.14 ORY00462.1 - 1.1e-48 164.5 0.0 1.8e-48 163.9 0.0 1.3 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 ORY00462.1 - 0.00015 21.6 0.0 0.00044 20.2 0.0 1.7 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 ORY00462.1 - 0.011 16.0 0.0 0.022 15.1 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like Redoxin PF08534.10 ORY00462.1 - 0.021 14.5 0.1 0.25 11.0 0.1 2.3 1 1 0 1 1 1 0 Redoxin MFS_1 PF07690.16 ORY00463.1 - 5.4e-46 157.1 24.3 5.4e-46 157.1 24.3 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY00463.1 - 6.3e-12 45.1 17.8 3.4e-11 42.7 17.9 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter YbgT_YccB PF08173.11 ORY00463.1 - 0.066 13.4 0.4 0.066 13.4 0.4 2.0 2 0 0 2 2 2 0 Membrane bound YbgT-like protein DUF389 PF04087.14 ORY00463.1 - 0.6 10.1 6.9 0.86 9.6 0.0 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF389) APH PF01636.23 ORY00535.1 - 0.00055 19.9 0.1 0.077 12.9 0.1 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase PF00069.25 ORY00535.1 - 0.00092 18.7 0.0 0.0026 17.1 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Choline_kinase PF01633.20 ORY00535.1 - 0.0086 15.7 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 ORY00535.1 - 0.014 14.8 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 ORY00535.1 - 0.031 13.9 0.0 0.044 13.4 0.0 1.3 1 1 0 1 1 1 0 RIO1 family Pkinase_Tyr PF07714.17 ORY00535.1 - 0.11 11.7 0.0 0.11 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase DUF3045 PF11243.8 ORY00537.1 - 0.021 15.0 0.0 0.038 14.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3045) bVLRF1 PF18826.1 ORY00537.1 - 1.1 9.1 4.4 6 6.7 0.1 2.7 3 0 0 3 3 3 0 bacteroidetes VLRF1 release factor STE3 PF02076.15 ORY00539.1 - 0.035 13.3 0.1 0.053 12.7 0.1 1.2 1 0 0 1 1 1 0 Pheromone A receptor AATase PF07247.12 ORY00540.1 - 1.4e-10 40.3 0.0 1.7e-10 40.1 0.0 1.0 1 0 0 1 1 1 1 Alcohol acetyltransferase CcmD PF04995.14 ORY00541.1 - 0.0083 16.2 0.6 0.012 15.7 0.6 1.3 1 0 0 1 1 1 1 Heme exporter protein D (CcmD) DUF4448 PF14610.6 ORY00541.1 - 0.11 12.2 0.2 0.17 11.6 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) FMO-like PF00743.19 ORY00542.1 - 2.7e-18 65.7 0.0 9.5e-17 60.6 0.0 2.2 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 ORY00542.1 - 1.8e-13 50.5 0.2 1.5e-10 40.9 0.1 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ORY00542.1 - 6.8e-10 38.7 0.0 4.3e-07 29.5 0.0 2.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ORY00542.1 - 7.2e-10 38.5 0.5 1.3e-05 24.5 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 ORY00542.1 - 9.8e-08 32.1 0.0 4.1e-07 30.1 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ORY00542.1 - 1.1e-06 28.5 0.0 2.1e-05 24.3 0.0 2.4 2 1 1 3 3 3 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 ORY00542.1 - 0.00023 21.2 0.0 0.0024 17.9 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.17 ORY00542.1 - 0.0048 16.2 0.3 0.016 14.5 0.1 1.8 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 ORY00542.1 - 0.0062 15.7 0.3 0.0097 15.0 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain Shikimate_DH PF01488.20 ORY00542.1 - 0.0078 16.3 0.0 5.1 7.2 0.1 2.3 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 ORY00542.1 - 0.0099 15.2 0.1 0.92 8.7 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain NAD_binding_7 PF13241.6 ORY00542.1 - 0.12 12.8 0.0 0.83 10.1 0.0 2.2 2 0 0 2 2 2 0 Putative NAD(P)-binding Lycopene_cycl PF05834.12 ORY00542.1 - 0.13 11.2 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Glyco_hydro_3_C PF01915.22 ORY00543.1 - 2.3e-54 184.4 0.9 4e-54 183.7 0.2 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 ORY00543.1 - 4.7e-45 154.3 0.0 7.3e-45 153.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 ORY00543.1 - 4.2e-26 90.9 0.0 7.6e-26 90.0 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF3372 PF11852.8 ORY00543.1 - 0.15 11.5 0.5 0.27 10.7 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3372) Zn_clus PF00172.18 ORY00544.1 - 1.4e-06 28.3 29.3 6.4e-06 26.2 16.1 3.3 2 1 1 3 3 3 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Mitofilin PF09731.9 ORY00544.1 - 0.22 10.3 3.1 0.34 9.7 3.1 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein SRP-alpha_N PF04086.13 ORY00544.1 - 6.2 6.7 10.0 8.7 6.2 10.0 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Ras PF00071.22 ORY00545.1 - 9.7e-53 178.1 0.0 1.2e-52 177.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY00545.1 - 5.8e-19 68.5 0.0 7.9e-19 68.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY00545.1 - 2.8e-06 26.9 0.0 3.9e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Spectrin PF00435.21 ORY00546.1 - 0.0034 17.8 4.1 0.61 10.6 0.2 2.4 1 1 1 2 2 2 2 Spectrin repeat Laminin_II PF06009.12 ORY00546.1 - 0.05 13.6 1.7 0.087 12.8 1.7 1.3 1 0 0 1 1 1 0 Laminin Domain II FragX_IP PF05994.11 ORY00546.1 - 0.076 11.1 0.2 0.1 10.6 0.2 1.1 1 0 0 1 1 1 0 Cytoplasmic Fragile-X interacting family DUF948 PF06103.11 ORY00546.1 - 0.21 11.9 2.6 1.5 9.2 0.0 2.6 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF16 PF01519.16 ORY00546.1 - 0.4 11.2 2.1 0.98 9.9 2.1 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF16 Myosin_tail_1 PF01576.19 ORY00546.1 - 0.5 8.1 3.3 0.68 7.7 3.3 1.1 1 0 0 1 1 1 0 Myosin tail Pkinase PF00069.25 ORY00547.1 - 8.8e-42 143.3 0.0 4.7e-41 140.9 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY00547.1 - 1.3e-24 86.9 0.0 1.8e-24 86.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORY00547.1 - 0.0062 15.4 0.0 0.01 14.6 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase TMPIT PF07851.13 ORY00548.1 - 5.2 6.2 6.5 7.5 5.7 6.5 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF4407 PF14362.6 ORY00548.1 - 8 5.7 9.1 2.7 7.2 5.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Pkinase PF00069.25 ORY00549.1 - 3.3e-24 85.7 0.0 4.7e-24 85.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY00549.1 - 9.1e-15 54.6 0.0 3.5e-14 52.7 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY00549.1 - 0.0087 15.4 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 ORY00549.1 - 0.025 14.5 0.1 0.072 13.0 0.1 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.25 ORY00551.1 - 9.8e-21 74.3 0.0 2.2e-20 73.1 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY00551.1 - 9e-11 41.5 0.0 3e-10 39.8 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase DUF1492 PF07374.11 ORY00551.1 - 0.15 12.2 0.0 0.38 10.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1492) CorA PF01544.18 ORY00553.1 - 0.00024 20.5 0.0 0.00031 20.2 0.0 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF2207 PF09972.9 ORY00553.1 - 0.054 12.3 0.1 0.07 11.9 0.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Pkinase PF00069.25 ORY00554.1 - 2.3e-21 76.3 0.0 3.1e-20 72.7 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY00554.1 - 1.7e-08 34.1 0.0 3.1e-07 30.0 0.0 2.4 1 1 0 1 1 1 1 Protein tyrosine kinase PTS_EIIC PF02378.18 ORY00555.1 - 0.057 12.4 5.5 0.067 12.2 5.5 1.1 1 0 0 1 1 1 0 Phosphotransferase system, EIIC UL2 PF08196.11 ORY00555.1 - 0.098 12.6 1.2 0.27 11.2 1.2 1.7 1 0 0 1 1 1 0 UL2 protein Ank_2 PF12796.7 ORY00556.1 - 0.16 12.6 0.0 0.69 10.5 0.0 2.0 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) WEMBL PF05701.11 ORY00590.1 - 0.0019 17.0 21.1 0.0039 15.9 21.1 1.4 1 0 0 1 1 1 1 Weak chloroplast movement under blue light ALIX_LYPXL_bnd PF13949.6 ORY00590.1 - 0.002 17.5 22.2 0.002 17.5 22.2 2.6 2 1 1 3 3 3 1 ALIX V-shaped domain binding to HIV V_ATPase_I PF01496.19 ORY00590.1 - 0.12 10.3 17.3 0.025 12.5 14.1 1.4 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DASH_Dam1 PF08653.10 ORY00590.1 - 0.16 11.8 0.1 0.16 11.8 0.1 3.0 3 0 0 3 3 3 0 DASH complex subunit Dam1 ZapB PF06005.12 ORY00590.1 - 0.26 11.8 48.2 0.071 13.6 15.6 5.6 3 3 2 5 5 5 0 Cell division protein ZapB bZIP_1 PF00170.21 ORY00590.1 - 1.3 9.2 17.6 0.93 9.6 1.6 4.2 2 1 3 5 5 5 0 bZIP transcription factor PKcGMP_CC PF16808.5 ORY00590.1 - 3.2 7.7 10.1 13 5.7 0.1 4.5 4 0 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase TMF_DNA_bd PF12329.8 ORY00590.1 - 5.6 7.0 33.6 4.2 7.4 1.8 5.7 3 1 2 5 5 5 0 TATA element modulatory factor 1 DNA binding Phlebovirus_NSM PF07246.11 ORY00590.1 - 7.1 5.9 18.8 1.1 8.6 4.5 2.5 1 1 1 2 2 2 0 Phlebovirus nonstructural protein NS-M PHM7_cyt PF14703.6 ORY00590.1 - 8.1 6.6 18.6 0.13 12.5 0.8 2.8 2 1 1 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter TMF_TATA_bd PF12325.8 ORY00590.1 - 9.1 6.5 30.7 0.059 13.6 11.0 3.9 2 1 2 4 4 4 0 TATA element modulatory factor 1 TATA binding adh_short PF00106.25 ORY00591.1 - 6.7e-37 126.9 0.3 9.9e-37 126.3 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY00591.1 - 7.2e-27 94.5 0.2 1.1e-26 93.8 0.2 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY00591.1 - 9.3e-06 25.7 3.4 0.0004 20.3 3.3 2.3 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 ORY00591.1 - 0.12 11.8 0.0 0.21 11.0 0.0 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Patatin PF01734.22 ORY00592.1 - 6.6e-22 78.7 0.0 4.7e-21 75.9 0.0 2.2 1 1 0 1 1 1 1 Patatin-like phospholipase MDM10 PF12519.8 ORY00592.1 - 0.19 10.5 0.0 0.27 10.0 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 WW PF00397.26 ORY00593.1 - 1.5e-06 28.2 0.3 2.9e-06 27.2 0.3 1.6 1 0 0 1 1 1 1 WW domain S-AdoMet_synt_C PF02773.16 ORY00594.1 - 1.9e-67 225.5 0.5 9.1e-67 223.3 0.0 1.9 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 ORY00594.1 - 1.1e-45 154.8 0.0 1.7e-45 154.1 0.0 1.3 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 ORY00594.1 - 9.7e-15 55.1 0.2 3.6e-14 53.2 0.0 2.0 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain ATP_bind_1 PF03029.17 ORY00595.1 - 6e-79 265.2 0.0 8.8e-79 264.7 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein CLP1_P PF16575.5 ORY00595.1 - 3.1e-05 23.9 0.0 5.7e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_14 PF13173.6 ORY00595.1 - 0.0017 18.4 0.0 0.0041 17.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ORY00595.1 - 0.0018 18.7 0.0 0.12 12.8 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 ORY00595.1 - 0.0063 17.1 0.0 0.017 15.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 ORY00595.1 - 0.0073 16.0 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 ORY00595.1 - 0.0075 16.5 0.0 0.016 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 ORY00595.1 - 0.0088 16.4 0.0 0.019 15.4 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_30 PF13604.6 ORY00595.1 - 0.023 14.4 0.0 0.073 12.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 ORY00595.1 - 0.026 15.0 0.0 0.071 13.6 0.0 1.6 2 0 0 2 2 1 0 ABC transporter RsgA_GTPase PF03193.16 ORY00595.1 - 0.033 14.1 0.0 0.25 11.2 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase AAA_33 PF13671.6 ORY00595.1 - 0.037 14.2 0.0 0.064 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 ORY00595.1 - 0.043 13.7 0.0 0.083 12.8 0.0 1.4 1 0 0 1 1 1 0 NACHT domain ATPase PF06745.13 ORY00595.1 - 0.043 13.2 0.0 0.1 11.9 0.0 1.6 2 0 0 2 2 2 0 KaiC AAA PF00004.29 ORY00595.1 - 0.052 14.0 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 ORY00595.1 - 0.053 13.0 0.0 0.13 11.8 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_19 PF13245.6 ORY00595.1 - 0.056 13.8 0.0 0.86 9.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 ORY00595.1 - 0.067 12.9 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 ORY00595.1 - 0.068 12.9 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain CbiA PF01656.23 ORY00595.1 - 0.079 13.0 0.0 0.11 12.6 0.0 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ATPase_2 PF01637.18 ORY00595.1 - 0.097 12.6 0.0 0.29 11.0 0.0 1.7 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea MMR_HSR1 PF01926.23 ORY00595.1 - 0.097 12.8 0.0 0.39 10.8 0.0 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_PrkA PF08298.11 ORY00595.1 - 0.1 11.5 0.0 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 PrkA AAA domain GTP_EFTU PF00009.27 ORY00595.1 - 0.12 11.9 0.0 14 5.1 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Cytidylate_kin PF02224.18 ORY00595.1 - 0.12 12.0 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 Cytidylate kinase MeaB PF03308.16 ORY00595.1 - 0.13 11.2 0.0 0.64 9.0 0.0 1.8 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB KAP_NTPase PF07693.14 ORY00595.1 - 0.14 11.4 0.0 0.19 10.9 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain T2SSE PF00437.20 ORY00595.1 - 0.14 11.2 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein cobW PF02492.19 ORY00595.1 - 0.16 11.5 0.0 2.5 7.7 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SRP54 PF00448.22 ORY00595.1 - 0.18 11.4 0.0 0.44 10.1 0.0 1.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain TsaE PF02367.17 ORY00595.1 - 0.2 11.6 0.0 0.36 10.8 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Thymidylate_kin PF02223.17 ORY00595.1 - 0.2 11.3 0.0 0.36 10.5 0.0 1.4 1 0 0 1 1 1 0 Thymidylate kinase Ppx-GppA PF02541.16 ORY00596.1 - 5.5e-46 157.3 0.0 8.8e-46 156.6 0.0 1.3 1 0 0 1 1 1 1 Ppx/GppA phosphatase family GDA1_CD39 PF01150.17 ORY00596.1 - 0.0028 16.4 0.1 0.0056 15.4 0.1 1.4 2 0 0 2 2 2 1 GDA1/CD39 (nucleoside phosphatase) family ELFV_dehydrog PF00208.21 ORY00597.1 - 4.4e-68 229.6 0.0 6.8e-68 229.0 0.0 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 ORY00597.1 - 6.9e-16 57.0 0.0 1.8e-10 39.1 0.0 2.1 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.18 ORY00597.1 - 0.18 11.7 0.0 0.61 10.0 0.0 1.8 2 0 0 2 2 2 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Asp4 PF16996.5 ORY00598.1 - 0.36 10.6 12.7 0.36 10.7 1.4 2.6 1 1 1 2 2 2 0 Accessory secretory protein Sec Asp4 Rft-1 PF04506.13 ORY00599.1 - 4.2e-149 497.6 1.0 4.8e-149 497.4 1.0 1.0 1 0 0 1 1 1 1 Rft protein Polysacc_synt_3 PF13440.6 ORY00599.1 - 0.087 12.0 0.0 0.087 12.0 0.0 2.9 4 0 0 4 4 4 0 Polysaccharide biosynthesis protein Acetyltransf_3 PF13302.7 ORY00600.1 - 5.5e-25 88.6 0.0 6.9e-25 88.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORY00600.1 - 0.00069 19.8 0.0 0.00098 19.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family SSF PF00474.17 ORY00601.1 - 4.5e-19 68.6 27.2 7.3e-19 67.9 27.2 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family Peptidase_M20 PF01546.28 ORY00602.1 - 8.6e-11 41.9 0.1 2.2e-10 40.6 0.1 1.8 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Malic_M PF03949.15 ORY00603.1 - 8.3e-94 313.6 0.0 1e-93 313.3 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 ORY00603.1 - 6.6e-61 205.3 0.0 1e-60 204.6 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain DUF4449 PF14613.6 ORY00604.1 - 0.00025 21.2 0.0 0.00025 21.2 0.0 3.1 4 1 0 4 4 4 1 Protein of unknown function (DUF4449) AbiH PF14253.6 ORY00604.1 - 0.015 15.2 2.6 0.02 14.8 0.9 1.9 2 0 0 2 2 2 0 Bacteriophage abortive infection AbiH EntA_Immun PF08951.10 ORY00604.1 - 0.057 13.8 0.3 5 7.6 0.0 3.0 3 0 0 3 3 3 0 Enterocin A Immunity Ku_PK_bind PF08785.11 ORY00604.1 - 0.27 11.4 1.9 3.7 7.7 0.2 2.8 2 0 0 2 2 2 0 Ku C terminal domain like Homeobox_KN PF05920.11 ORY00605.1 - 5.2e-09 35.9 0.3 1.7e-08 34.2 0.3 1.9 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 ORY00605.1 - 6.1e-09 35.6 1.0 1.6e-08 34.3 1.0 1.7 1 0 0 1 1 1 1 Homeodomain zf-C2H2_4 PF13894.6 ORY00605.1 - 0.00032 21.3 24.7 0.0019 18.9 1.2 5.4 5 1 1 6 6 6 3 C2H2-type zinc finger zf-C2H2 PF00096.26 ORY00605.1 - 0.014 15.8 18.0 0.033 14.6 1.5 4.7 4 0 0 4 4 4 0 Zinc finger, C2H2 type Rep_fac-A_C PF08646.10 ORY00605.1 - 0.12 12.1 1.8 2.2 8.0 0.2 2.4 1 1 1 2 2 2 0 Replication factor-A C terminal domain zf-DBF PF07535.12 ORY00605.1 - 0.16 12.1 3.7 0.41 10.8 3.7 1.6 1 0 0 1 1 1 0 DBF zinc finger zf-C2H2_2 PF12756.7 ORY00605.1 - 3.4 8.1 9.5 10 6.5 0.1 3.9 3 1 1 4 4 4 0 C2H2 type zinc-finger (2 copies) PDZ_1 PF12812.7 ORY00606.1 - 8.7e-60 198.7 0.0 5.9e-36 122.3 0.0 2.7 2 0 0 2 2 2 2 PDZ-like domain Trypsin_2 PF13365.6 ORY00606.1 - 5.8e-25 88.9 0.5 1.2e-21 78.2 0.1 2.4 2 0 0 2 2 2 2 Trypsin-like peptidase domain PDZ_6 PF17820.1 ORY00606.1 - 1.9e-13 50.1 0.3 2.2e-06 27.4 0.4 4.4 4 0 0 4 4 4 2 PDZ domain PDZ_2 PF13180.6 ORY00606.1 - 1.6e-10 41.1 0.2 0.00021 21.6 0.1 3.7 3 0 0 3 3 3 2 PDZ domain PDZ PF00595.24 ORY00606.1 - 1.2e-08 35.2 0.0 0.00041 20.6 0.0 3.4 3 0 0 3 3 3 2 PDZ domain Trypsin PF00089.26 ORY00606.1 - 7.6e-07 29.2 0.0 2.5e-06 27.5 0.0 1.8 1 1 0 1 1 1 1 Trypsin Peptidase_S46 PF10459.9 ORY00606.1 - 0.018 13.7 0.1 0.037 12.7 0.1 1.4 1 0 0 1 1 1 0 Peptidase S46 Peptidase_S7 PF00949.21 ORY00606.1 - 0.023 14.5 0.1 0.053 13.3 0.1 1.5 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease Tricorn_PDZ PF14685.6 ORY00606.1 - 0.032 14.2 0.4 0.74 9.8 0.1 2.8 3 0 0 3 3 3 0 Tricorn protease PDZ domain DUF31 PF01732.16 ORY00606.1 - 0.033 13.7 0.4 0.057 13.0 0.4 1.3 1 0 0 1 1 1 0 Putative peptidase (DUF31) 4HPAD_g_N PF18671.1 ORY00606.1 - 0.048 13.4 0.0 0.37 10.5 0.0 2.4 2 0 0 2 2 2 0 4-Hydroxyphenylacetate decarboxylase subunit gamma N-terminal Fungal_trans_2 PF11951.8 ORY00608.1 - 6.4e-09 35.1 0.0 1.3e-06 27.5 0.0 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY00608.1 - 1.8e-07 31.1 9.9 3.3e-07 30.3 9.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2114 PF09887.9 ORY00609.1 - 0.076 11.5 0.0 0.094 11.2 0.0 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2114) p450 PF00067.22 ORY00610.1 - 6.1e-67 226.4 0.0 8.9e-67 225.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 NTPase_1 PF03266.15 ORY00610.1 - 0.15 12.0 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 NTPase Glyco_transf_20 PF00982.21 ORY00611.1 - 9.3e-201 667.6 0.0 1.1e-200 667.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glyco_trans_1_4 PF13692.6 ORY00611.1 - 0.00014 22.3 0.0 0.00035 21.0 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 ORY00611.1 - 0.005 16.6 0.0 0.0096 15.6 0.0 1.5 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 ORY00611.1 - 0.011 15.3 0.5 0.16 11.5 0.1 2.6 2 1 0 2 2 2 0 Glycosyl transferases group 1 PKcGMP_CC PF16808.5 ORY00611.1 - 0.49 10.3 2.6 0.59 10.0 0.4 2.2 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF5310 PF17237.2 ORY00613.1 - 5.4e-21 74.2 0.7 6.2e-21 74.0 0.7 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5310) Adaptin_N PF01602.20 ORY00614.1 - 4.2e-137 457.9 1.7 5.4e-137 457.5 1.7 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 ORY00614.1 - 1.1e-64 217.4 3.3 7.3e-62 208.2 0.5 2.9 3 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 ORY00614.1 - 1.9e-15 57.0 0.3 5.8e-06 26.6 0.0 5.2 3 2 2 5 5 5 3 HEAT repeats HEAT PF02985.22 ORY00614.1 - 1.7e-12 46.5 2.8 0.011 15.9 0.0 6.7 7 0 0 7 7 7 3 HEAT repeat Arm PF00514.23 ORY00614.1 - 0.00092 19.2 1.2 36 4.6 0.0 5.7 4 1 1 5 5 5 0 Armadillo/beta-catenin-like repeat CLASP_N PF12348.8 ORY00614.1 - 0.0017 18.0 0.1 1.5 8.3 0.0 3.5 2 1 1 3 3 3 1 CLASP N terminal HEAT_EZ PF13513.6 ORY00614.1 - 0.0042 17.6 0.9 2.5 8.7 0.0 4.8 4 1 1 5 5 5 1 HEAT-like repeat UNC45-central PF11701.8 ORY00614.1 - 0.0069 16.4 0.1 2.8 7.9 0.0 3.0 2 1 0 2 2 2 1 Myosin-binding striated muscle assembly central Sec7_N PF12783.7 ORY00614.1 - 0.038 13.9 0.5 0.13 12.2 0.1 2.2 2 0 0 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF5578 PF17741.1 ORY00614.1 - 0.27 10.6 5.0 7.6 5.9 0.1 3.4 2 1 2 4 4 4 0 Family of unknown function (DUF5578) VID27 PF08553.10 ORY00615.1 - 9.3e-190 630.2 0.1 1.2e-189 629.8 0.1 1.1 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain VID27_N PF17748.1 ORY00615.1 - 4.8e-74 247.9 0.2 4.8e-74 247.9 0.2 3.0 2 1 1 3 3 3 1 VID27 N-terminal region VID27_PH PF17747.1 ORY00615.1 - 1.3e-44 151.0 1.3 4.1e-44 149.3 0.5 2.1 2 0 0 2 2 2 1 VID27 PH-like domain UPF0149 PF03695.13 ORY00615.1 - 0.17 12.2 4.3 0.2 11.9 2.5 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0149) DNA_pol_phi PF04931.13 ORY00615.1 - 8.6 4.3 14.3 12 3.8 14.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi ATP19 PF11022.8 ORY00651.1 - 9.9 6.6 5.4 4.4 7.8 0.0 3.0 3 0 0 3 3 3 0 ATP synthase subunit K GMC_oxred_N PF00732.19 ORY00652.1 - 1.2e-24 87.2 0.0 2.8e-24 86.0 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 ORY00652.1 - 6.3e-24 85.1 0.2 1.4e-23 84.0 0.2 1.6 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 ORY00652.1 - 1e-10 41.3 0.1 0.00024 20.3 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 ORY00652.1 - 5.7e-05 23.3 0.1 0.00023 21.3 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ORY00652.1 - 0.00067 19.0 0.0 0.0022 17.3 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ORY00652.1 - 0.00098 18.8 0.1 0.019 14.6 0.0 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 ORY00652.1 - 0.0033 16.9 0.0 1.7 7.9 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.14 ORY00652.1 - 0.011 14.5 0.0 0.015 14.0 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.6 ORY00652.1 - 0.018 14.3 0.2 0.048 12.9 0.1 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 ORY00652.1 - 0.022 13.8 0.0 0.033 13.2 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_3 PF01494.19 ORY00652.1 - 0.088 12.0 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Peptidase_M50B PF13398.6 ORY00652.1 - 0.13 11.8 1.2 0.28 10.8 1.2 1.4 1 0 0 1 1 1 0 Peptidase M50B-like Thi4 PF01946.17 ORY00652.1 - 0.14 11.4 0.2 0.25 10.5 0.2 1.4 1 0 0 1 1 1 0 Thi4 family MTHFR PF02219.17 ORY00653.1 - 3.9e-115 384.1 0.0 5.3e-115 383.7 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase TIM PF00121.18 ORY00654.1 - 9.5e-52 175.8 0.0 1.1e-51 175.6 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase Fe-ADH PF00465.19 ORY00655.1 - 1.4e-64 218.2 0.0 1.8e-64 217.8 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 ORY00655.1 - 6.8e-14 52.2 0.0 9.5e-14 51.7 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase bZIP_1 PF00170.21 ORY00657.1 - 3.1e-08 33.6 5.9 3.1e-08 33.6 5.9 1.7 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 ORY00657.1 - 0.00016 21.7 5.8 0.00016 21.7 5.8 1.9 2 0 0 2 2 2 1 Basic region leucine zipper SHE3 PF17078.5 ORY00657.1 - 0.0016 18.2 2.8 0.0019 18.0 1.9 1.4 1 1 0 1 1 1 1 SWI5-dependent HO expression protein 3 bZIP_Maf PF03131.17 ORY00657.1 - 0.0025 18.3 6.7 0.0025 18.3 6.7 1.5 2 0 0 2 2 2 1 bZIP Maf transcription factor CENP-H PF05837.12 ORY00657.1 - 0.0059 17.0 2.9 0.0079 16.6 2.9 1.3 1 0 0 1 1 1 1 Centromere protein H (CENP-H) PspA_IM30 PF04012.12 ORY00657.1 - 0.0098 15.5 4.2 0.014 15.0 4.2 1.1 1 0 0 1 1 1 1 PspA/IM30 family DUF4407 PF14362.6 ORY00657.1 - 0.018 14.4 3.9 0.023 14.0 3.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Nucleo_P87 PF07267.11 ORY00657.1 - 0.042 12.7 1.5 0.049 12.5 1.5 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 GvpL_GvpF PF06386.11 ORY00657.1 - 0.051 13.5 4.4 0.058 13.3 3.7 1.4 1 1 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF V_ATPase_I PF01496.19 ORY00657.1 - 0.11 10.4 1.6 0.12 10.2 1.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2951 PF11166.8 ORY00657.1 - 0.21 11.8 1.3 0.29 11.4 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) YabA PF06156.13 ORY00657.1 - 0.21 12.2 1.3 0.32 11.6 1.3 1.3 1 0 0 1 1 1 0 Initiation control protein YabA M PF02370.16 ORY00657.1 - 0.3 11.8 1.5 5.5 7.9 0.2 2.5 1 1 1 2 2 2 0 M protein repeat DUF4140 PF13600.6 ORY00659.1 - 1.2 9.6 6.6 4.4 7.8 4.8 2.5 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) adh_short PF00106.25 ORY00661.1 - 1.1e-81 272.9 8.1 2.3e-43 148.0 1.8 2.4 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 ORY00661.1 - 1.1e-65 221.4 3.2 6.9e-35 120.7 0.6 2.8 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase MaoC_dehydratas PF01575.19 ORY00661.1 - 2.7e-34 117.4 0.0 6.4e-34 116.2 0.0 1.6 1 0 0 1 1 1 1 MaoC like domain KR PF08659.10 ORY00661.1 - 2.7e-27 95.8 3.8 3.5e-14 53.1 0.2 2.4 2 0 0 2 2 2 2 KR domain THF_DHG_CYH_C PF02882.19 ORY00661.1 - 0.003 16.9 1.2 0.014 14.7 0.1 2.2 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain MaoC_dehydrat_N PF13452.6 ORY00661.1 - 0.015 15.4 0.0 2.2 8.4 0.0 2.7 3 0 0 3 3 3 0 N-terminal half of MaoC dehydratase PRK PF00485.18 ORY00662.1 - 9.5e-05 22.2 0.0 0.00015 21.6 0.0 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.6 ORY00662.1 - 0.0032 17.6 0.0 0.0092 16.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain cobW PF02492.19 ORY00662.1 - 0.025 14.1 0.0 0.038 13.6 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain TsaE PF02367.17 ORY00662.1 - 0.034 14.1 0.0 0.069 13.2 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MobB PF03205.14 ORY00662.1 - 0.047 13.6 0.0 0.32 10.9 0.0 2.1 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B KAP_NTPase PF07693.14 ORY00662.1 - 0.052 12.8 0.0 0.07 12.4 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain NACHT PF05729.12 ORY00662.1 - 0.056 13.4 0.0 0.091 12.7 0.0 1.3 1 0 0 1 1 1 0 NACHT domain SRP54 PF00448.22 ORY00662.1 - 0.063 12.9 0.0 0.11 12.1 0.0 1.4 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_18 PF13238.6 ORY00662.1 - 0.066 13.8 0.0 0.24 11.9 0.0 2.0 2 1 0 2 2 2 0 AAA domain MeaB PF03308.16 ORY00662.1 - 0.079 11.9 0.0 0.17 10.9 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ABC_tran PF00005.27 ORY00662.1 - 0.1 13.1 0.0 0.18 12.3 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Septin PF00735.18 ORY00662.1 - 0.13 11.5 0.0 0.23 10.7 0.0 1.5 1 0 0 1 1 1 0 Septin NB-ARC PF00931.22 ORY00662.1 - 0.14 11.3 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA PF00004.29 ORY00662.1 - 0.19 12.1 0.0 0.35 11.3 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 ORY00662.1 - 0.19 11.7 0.0 0.38 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Methyltransf_23 PF13489.6 ORY00663.1 - 1.4e-13 51.1 0.0 1.9e-13 50.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY00663.1 - 3.9e-09 37.1 0.0 7.7e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY00663.1 - 1.8e-06 28.5 0.0 3.5e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY00663.1 - 2.5e-05 24.9 0.0 4.8e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY00663.1 - 7.3e-05 22.6 0.0 0.00011 22.1 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 ORY00663.1 - 0.0069 15.9 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase FtsJ PF01728.19 ORY00663.1 - 0.022 14.9 0.0 0.1 12.7 0.0 1.8 2 0 0 2 2 2 0 FtsJ-like methyltransferase MTS PF05175.14 ORY00663.1 - 0.07 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Lipase_GDSL PF00657.22 ORY00664.1 - 4e-11 43.3 0.0 5.9e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 ORY00664.1 - 3.5e-06 27.5 0.8 1.9e-05 25.1 0.8 2.2 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Urocanase PF01175.18 ORY00665.1 - 0.13 11.9 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 Urocanase Rossmann-like domain DUF1998 PF09369.10 ORY00666.1 - 2.6e-19 69.8 1.6 9.5e-19 67.9 1.6 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) DEAD PF00270.29 ORY00666.1 - 3.8e-15 56.1 0.0 6.6e-15 55.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY00666.1 - 1.7e-13 50.9 0.0 5.8e-13 49.2 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CDT1 PF08839.11 ORY00666.1 - 9e-07 29.3 0.2 1.7e-06 28.4 0.2 1.5 1 0 0 1 1 1 1 DNA replication factor CDT1 like HD_3 PF13023.6 ORY00668.1 - 6.2e-50 169.4 0.2 9.7e-50 168.7 0.2 1.3 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 ORY00668.1 - 1e-13 51.4 0.1 1.4e-13 51.1 0.1 1.2 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme eIF3g PF12353.8 ORY00668.1 - 0.072 13.5 0.1 1.5 9.2 0.1 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G HD PF01966.22 ORY00668.1 - 0.12 12.6 0.0 0.29 11.4 0.0 1.6 1 1 0 1 1 1 0 HD domain HAUS6_N PF14661.6 ORY00669.1 - 8.8e-48 162.9 1.5 8.8e-48 162.9 1.5 1.8 2 0 0 2 2 2 1 HAUS augmin-like complex subunit 6 N-terminus P4Ha_N PF08336.11 ORY00669.1 - 0.12 12.4 1.0 0.21 11.6 0.1 1.9 2 0 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region SMC_N PF02463.19 ORY00671.1 - 9.9e-71 237.7 0.0 3.4e-70 235.9 0.0 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 ORY00671.1 - 1.9e-21 76.6 0.1 1.1e-20 74.1 0.1 2.4 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 ORY00671.1 - 6.3e-13 49.7 5.0 6.3e-13 49.7 5.0 6.8 2 2 3 5 5 5 1 AAA domain AAA_21 PF13304.6 ORY00671.1 - 2.1e-12 47.5 0.5 6.1e-05 23.0 0.0 3.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system MscS_porin PF12795.7 ORY00671.1 - 7.3e-05 22.4 30.5 7.3e-05 22.4 30.5 6.2 3 2 2 5 5 5 1 Mechanosensitive ion channel porin domain AAA_29 PF13555.6 ORY00671.1 - 9.9e-05 22.0 0.2 0.00023 20.8 0.2 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain HIP1_clath_bdg PF16515.5 ORY00671.1 - 0.006 17.2 10.0 0.006 17.2 10.0 9.6 3 2 5 9 9 9 1 Clathrin-binding domain of Huntingtin-interacting protein 1 ABC_tran PF00005.27 ORY00671.1 - 0.03 14.8 0.1 0.03 14.8 0.1 6.0 4 3 0 4 4 4 0 ABC transporter HSBP1 PF06825.12 ORY00671.1 - 2.3 8.1 13.6 0.066 13.1 0.4 5.1 5 0 0 5 5 5 0 Heat shock factor binding protein 1 OPT PF03169.15 ORY00672.1 - 1e-126 424.1 42.7 1.2e-126 423.9 42.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein ECM11 PF15463.6 ORY00673.1 - 3.5e-34 118.2 0.7 3.5e-34 118.2 0.7 2.7 3 0 0 3 3 3 1 Extracellular mutant protein 11 CPSase_L_D3 PF02787.19 ORY00673.1 - 0.039 14.3 0.3 0.097 13.0 0.3 1.6 1 0 0 1 1 1 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain NOA36 PF06524.12 ORY00673.1 - 1.3 8.3 13.6 2.1 7.6 13.6 1.3 1 0 0 1 1 1 0 NOA36 protein F-box-like PF12937.7 ORY00674.1 - 4.7e-06 26.4 1.2 1.1e-05 25.2 1.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY00674.1 - 0.011 15.6 0.4 0.022 14.6 0.4 1.5 1 0 0 1 1 1 0 F-box domain TPR_1 PF00515.28 ORY00732.1 - 3.2e-38 128.0 19.1 6.3e-07 29.0 0.1 8.4 8 1 1 9 9 9 6 Tetratricopeptide repeat TPR_2 PF07719.17 ORY00732.1 - 2.6e-33 111.4 16.7 4e-06 26.5 0.0 8.6 8 0 0 8 8 8 7 Tetratricopeptide repeat DnaJ PF00226.31 ORY00732.1 - 3.1e-27 94.5 5.3 3.1e-27 94.5 5.3 2.4 2 0 0 2 2 1 1 DnaJ domain TPR_16 PF13432.6 ORY00732.1 - 1.2e-24 86.7 4.9 4e-06 27.4 0.2 6.3 5 2 1 6 6 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 ORY00732.1 - 1.3e-24 85.5 14.8 6.9e-09 35.2 0.5 7.3 5 2 3 8 8 8 4 TPR repeat TPR_19 PF14559.6 ORY00732.1 - 9.2e-23 80.5 16.6 4.3e-06 27.1 0.1 6.3 4 3 2 6 6 5 5 Tetratricopeptide repeat TPR_14 PF13428.6 ORY00732.1 - 2.4e-17 62.1 11.6 0.00052 20.6 0.0 8.4 6 2 3 9 9 8 5 Tetratricopeptide repeat TPR_17 PF13431.6 ORY00732.1 - 1.1e-16 59.9 12.8 0.00051 20.2 0.6 6.8 7 0 0 7 7 6 5 Tetratricopeptide repeat TPR_8 PF13181.6 ORY00732.1 - 7.4e-16 57.0 13.6 0.018 15.2 0.0 7.4 7 1 0 7 7 6 5 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY00732.1 - 1.9e-14 53.6 5.3 0.00018 21.7 0.1 3.6 2 1 1 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 ORY00732.1 - 3.5e-13 49.6 11.8 0.013 15.8 0.1 6.7 4 2 1 6 6 6 4 Tetratricopeptide repeat TPR_9 PF13371.6 ORY00732.1 - 3.7e-12 46.2 4.5 0.00034 20.7 0.0 4.8 4 2 2 6 6 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 ORY00732.1 - 6.5e-09 35.2 10.9 0.3 11.2 0.0 7.3 7 1 0 7 7 6 3 Tetratricopeptide repeat TPR_6 PF13174.6 ORY00732.1 - 1.4e-08 34.8 13.9 0.17 12.6 0.1 8.2 8 1 1 9 9 8 2 Tetratricopeptide repeat TPR_15 PF13429.6 ORY00732.1 - 8.2e-08 31.8 4.5 0.036 13.3 0.0 3.5 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 ORY00732.1 - 1.6e-07 31.0 10.8 0.29 11.1 0.1 6.5 7 0 0 7 7 6 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 ORY00732.1 - 2.6e-07 30.6 6.7 1.2 9.3 0.1 5.6 4 2 2 6 6 5 2 Fis1 C-terminal tetratricopeptide repeat TPR_4 PF07721.14 ORY00732.1 - 1.2e-05 25.5 7.6 0.83 10.5 0.2 5.1 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_20 PF14561.6 ORY00732.1 - 1.8e-05 25.0 16.0 0.35 11.2 0.4 5.4 3 2 2 5 5 5 2 Tetratricopeptide repeat BTAD PF03704.17 ORY00732.1 - 8.4e-05 23.0 5.9 1.1 9.6 0.2 4.0 2 1 2 4 4 4 1 Bacterial transcriptional activator domain DUF3597 PF12200.8 ORY00732.1 - 0.00081 19.9 0.2 0.00081 19.9 0.2 3.8 3 2 1 4 4 2 1 Domain of unknown function (DUF3597) DUF3856 PF12968.7 ORY00732.1 - 0.0083 16.2 3.5 26 4.9 0.0 5.6 4 2 1 5 5 5 0 Domain of Unknown Function (DUF3856) Alkyl_sulf_dimr PF14863.6 ORY00732.1 - 0.0095 16.4 2.6 9.2 6.7 0.7 3.5 2 1 0 2 2 2 0 Alkyl sulfatase dimerisation ChAPs PF09295.10 ORY00732.1 - 0.014 14.4 1.2 0.17 10.9 0.0 2.6 2 1 1 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) RRM_3 PF08777.11 ORY00732.1 - 0.028 14.5 1.5 0.099 12.7 0.2 2.3 2 0 0 2 2 2 0 RNA binding motif TPR_21 PF09976.9 ORY00732.1 - 0.67 9.6 15.5 0.46 10.2 0.3 4.8 3 3 1 4 4 4 0 Tetratricopeptide repeat-like domain MIT PF04212.18 ORY00732.1 - 1.5 8.9 9.3 2.3 8.3 0.0 4.4 5 1 0 5 5 4 0 MIT (microtubule interacting and transport) domain PrsW-protease PF13367.6 ORY00733.1 - 0.032 13.7 0.2 0.046 13.2 0.2 1.2 1 0 0 1 1 1 0 PrsW family intramembrane metalloprotease BTB PF00651.31 ORY00737.1 - 0.14 12.4 0.0 0.31 11.3 0.0 1.6 1 1 0 1 1 1 0 BTB/POZ domain Cauli_VI PF01693.16 ORY00738.1 - 5.8e-08 32.9 0.1 9.4e-08 32.2 0.1 1.4 1 0 0 1 1 1 1 Caulimovirus viroplasmin DNA_ligase_A_N PF04675.14 ORY00741.1 - 1.8e-45 155.3 0.0 3.2e-45 154.6 0.0 1.4 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_M PF01068.21 ORY00741.1 - 5.9e-42 143.6 0.0 1.5e-41 142.3 0.0 1.7 1 0 0 1 1 1 1 ATP dependent DNA ligase domain BRCT_2 PF16589.5 ORY00741.1 - 1.7e-16 60.4 0.0 5.7e-13 49.1 0.0 2.7 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain DNA_ligase_A_C PF04679.15 ORY00741.1 - 2.4e-15 56.9 0.0 6.4e-15 55.6 0.0 1.8 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 ORY00741.1 - 6.4e-15 55.8 0.0 1.2e-14 54.9 0.0 1.5 1 0 0 1 1 1 1 RNA ligase BRCT PF00533.26 ORY00741.1 - 1.6e-09 38.0 0.1 3.4e-08 33.8 0.1 2.6 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 ORY00741.1 - 3.7e-07 30.4 0.0 0.00037 20.7 0.0 2.5 2 0 0 2 2 2 2 DNA ligase 3 BRCT domain DNA_ligase_IV PF11411.8 ORY00741.1 - 7.7e-06 25.9 0.0 2.2e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 DNA ligase IV EF-hand_4 PF12763.7 ORY00742.1 - 0.0011 18.9 0.0 0.0019 18.1 0.0 1.3 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand Cupin_8 PF13621.6 ORY00743.1 - 1.7e-66 224.6 0.2 2.2e-66 224.2 0.2 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 ORY00743.1 - 1e-06 28.4 0.0 6.2e-05 22.6 0.0 2.4 2 0 0 2 2 2 2 Cupin superfamily protein KSHV_K8 PF07188.11 ORY00743.1 - 0.011 15.2 0.0 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 Kaposi's sarcoma-associated herpesvirus (KSHV) K8 protein Peptidase_S26 PF10502.9 ORY00744.1 - 4.6e-05 23.2 0.0 0.00011 22.0 0.0 1.7 1 1 0 1 1 1 1 Signal peptidase, peptidase S26 Peptidase_S24 PF00717.23 ORY00744.1 - 0.00056 19.8 0.5 0.0034 17.3 0.5 2.2 1 1 0 1 1 1 1 Peptidase S24-like S4_2 PF13275.6 ORY00744.1 - 0.06 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 S4 domain Peptidase_M35 PF02102.15 ORY00746.1 - 1.7e-107 359.5 18.1 1.8e-107 359.3 18.1 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.6 ORY00746.1 - 2.5e-40 138.4 3.1 2.5e-40 138.4 3.1 1.7 1 1 1 2 2 2 1 Lysine-specific metallo-endopeptidase Ig_GlcNase PF18368.1 ORY00746.1 - 0.076 13.2 1.3 1.8 8.7 0.0 3.0 3 0 0 3 3 3 0 Exo-beta-D-glucosaminidase Ig-fold domain HET PF06985.11 ORY00747.1 - 3e-32 112.0 0.2 8.6e-32 110.5 0.2 1.7 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DHDPS PF00701.22 ORY00747.1 - 0.24 10.1 0.0 0.34 9.6 0.0 1.1 1 0 0 1 1 1 0 Dihydrodipicolinate synthetase family Glyco_hydro_62 PF03664.13 ORY00750.1 - 6.3e-149 494.7 15.2 7.3e-149 494.5 15.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 2OG-FeII_Oxy PF03171.20 ORY00818.1 - 0.00026 21.4 0.0 0.00052 20.5 0.0 1.4 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Ank_4 PF13637.6 ORY00819.1 - 9.9e-21 73.8 0.1 8.1e-10 39.0 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 ORY00819.1 - 1.8e-15 56.6 0.9 4.1e-05 23.8 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.7 ORY00819.1 - 9.8e-13 48.5 0.2 2.3e-12 47.3 0.2 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ORY00819.1 - 5.5e-07 29.4 0.0 0.11 13.1 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 ORY00819.1 - 1e-05 25.7 0.2 0.17 12.3 0.1 2.5 1 1 2 3 3 3 2 Ankyrin repeats (many copies) HicA_toxin PF07927.12 ORY00819.1 - 0.048 13.7 0.0 14 5.8 0.0 2.3 2 0 0 2 2 2 0 HicA toxin of bacterial toxin-antitoxin, Ribonuc_2-5A PF06479.12 ORY00821.1 - 0.062 13.5 0.1 0.068 13.4 0.1 1.1 1 0 0 1 1 1 0 Ribonuclease 2-5A DUF3435 PF11917.8 ORY00822.1 - 6.2e-13 48.5 3.1 6.5e-13 48.4 3.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) CorA PF01544.18 ORY00877.1 - 0.046 13.0 0.3 0.054 12.8 0.3 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein TauD PF02668.16 ORY00880.1 - 7.3e-27 94.8 0.1 3.4e-26 92.6 0.1 2.0 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF676 PF05057.14 ORY00881.1 - 0.0098 15.4 0.1 0.014 14.9 0.1 1.3 1 1 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 ORY00881.1 - 0.01 15.6 0.0 0.012 15.3 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein NB-ARC PF00931.22 ORY00882.1 - 2.7e-05 23.5 0.0 0.0021 17.3 0.0 2.0 2 0 0 2 2 2 2 NB-ARC domain AAA_16 PF13191.6 ORY00882.1 - 0.00019 21.9 0.9 0.00056 20.3 0.9 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 ORY00882.1 - 0.00049 20.4 0.0 0.00073 19.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 ORY00882.1 - 0.0052 16.4 0.1 0.01 15.4 0.1 1.6 1 1 0 1 1 1 1 AAA domain Epimerase PF01370.21 ORY00883.1 - 2.9e-08 33.5 0.0 0.0025 17.3 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 ORY00883.1 - 7.2e-06 25.3 0.0 1.2e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.19 ORY00883.1 - 0.0015 17.6 0.0 0.011 14.8 0.0 1.9 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 ORY00883.1 - 0.0018 18.7 0.0 0.0029 18.0 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 ORY00883.1 - 0.083 12.3 0.1 0.87 8.9 0.0 2.2 2 1 0 2 2 2 0 GDP-mannose 4,6 dehydratase NmrA PF05368.13 ORY00883.1 - 0.21 11.1 0.0 0.3 10.6 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family TPR_12 PF13424.6 ORY00884.1 - 1.1e-30 105.7 5.9 2.4e-16 59.8 1.4 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 ORY00884.1 - 3.8e-27 93.4 1.8 2.2e-12 46.4 0.1 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 ORY00884.1 - 2.5e-09 36.5 3.5 9.5e-05 22.2 0.1 4.1 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 ORY00884.1 - 8.9e-07 29.5 3.0 3.8e-05 24.2 1.3 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 ORY00884.1 - 2.7e-06 27.0 6.0 0.00058 19.6 0.0 3.8 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 ORY00884.1 - 3.1e-05 24.4 4.0 0.018 15.8 0.3 3.6 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_3 PF07720.12 ORY00884.1 - 0.00026 20.9 2.3 0.027 14.4 1.4 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 ORY00884.1 - 0.0021 18.0 8.0 0.12 12.5 0.1 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 ORY00884.1 - 0.0025 17.9 3.1 0.12 12.6 0.0 3.4 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_MalT PF17874.1 ORY00884.1 - 0.06 12.7 0.1 0.1 12.0 0.1 1.4 1 0 0 1 1 1 0 MalT-like TPR region MIT PF04212.18 ORY00884.1 - 0.093 12.8 2.8 8.1 6.6 0.2 2.8 2 1 1 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_6 PF13174.6 ORY00884.1 - 0.46 11.2 4.3 10 7.0 0.2 3.6 3 1 0 3 3 3 0 Tetratricopeptide repeat Ank_4 PF13637.6 ORY00885.1 - 3.1e-24 85.0 0.1 8.8e-09 35.7 0.1 4.9 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 ORY00885.1 - 3.8e-22 78.7 0.1 8.8e-10 39.1 0.7 3.1 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 ORY00885.1 - 4.7e-13 48.9 0.8 0.00068 20.0 0.0 6.3 5 1 0 5 5 5 2 Ankyrin repeat Ank_3 PF13606.6 ORY00885.1 - 1.4e-11 43.5 0.1 0.29 11.8 0.0 6.3 6 1 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 ORY00885.1 - 1.7e-11 44.1 1.4 0.04 14.2 0.3 5.0 1 1 3 4 4 4 4 Ankyrin repeats (many copies) NACHT PF05729.12 ORY00885.1 - 9e-07 29.0 0.0 1.8e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 ORY00885.1 - 1.2e-05 25.6 0.2 0.00038 20.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 ORY00885.1 - 0.18 12.2 0.1 0.78 10.2 0.1 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) C1_2 PF03107.16 ORY00885.1 - 0.43 10.9 4.4 1.4 9.3 4.4 1.9 1 0 0 1 1 1 0 C1 domain DUF2039 PF10217.9 ORY00885.1 - 0.94 9.9 4.5 3.9 7.9 3.3 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) Peptidase_C14 PF00656.22 ORY00886.1 - 9.1e-08 32.3 0.1 2.6e-06 27.6 0.0 2.1 1 1 1 2 2 2 2 Caspase domain Raptor_N PF14538.6 ORY00886.1 - 0.0077 16.2 0.0 0.018 15.0 0.0 1.6 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain FtsK_4TM PF13491.6 ORY00888.1 - 0.018 14.8 0.7 0.026 14.2 0.7 1.2 1 0 0 1 1 1 0 4TM region of DNA translocase FtsK/SpoIIIE Ferric_reduct PF01794.19 ORY00888.1 - 0.97 9.6 4.2 0.41 10.8 1.8 1.6 2 0 0 2 2 2 0 Ferric reductase like transmembrane component adh_short_C2 PF13561.6 ORY00891.1 - 9.4e-24 84.3 0.0 1.4e-23 83.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY00891.1 - 1e-14 54.5 0.2 1.4e-13 50.7 0.0 2.2 2 1 0 2 2 2 1 short chain dehydrogenase Fungal_trans PF04082.18 ORY00892.1 - 3.8e-11 42.5 0.1 6.2e-11 41.8 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain GMC_oxred_N PF00732.19 ORY00893.1 - 6e-49 167.0 0.1 2.7e-36 125.5 0.0 2.2 1 1 1 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.13 ORY00893.1 - 4.7e-26 92.0 0.0 7.6e-26 91.3 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 ORY00893.1 - 0.00075 19.7 0.5 0.0021 18.3 0.3 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 ORY00893.1 - 0.00077 18.6 0.1 0.0013 17.8 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 ORY00893.1 - 0.002 17.4 0.2 0.0043 16.3 0.2 1.5 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 ORY00893.1 - 0.009 15.1 1.2 0.058 12.5 0.6 2.3 3 0 0 3 3 3 1 FAD binding domain Pyr_redox_2 PF07992.14 ORY00893.1 - 0.033 13.4 0.1 0.08 12.2 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ORY00893.1 - 0.078 12.2 0.1 3.5 6.8 0.3 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ORY00893.1 - 0.097 12.2 2.4 0.21 11.1 2.4 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase Trp_halogenase PF04820.14 ORY00893.1 - 0.12 11.2 1.3 0.39 9.5 0.6 1.9 2 0 0 2 2 2 0 Tryptophan halogenase HI0933_like PF03486.14 ORY00893.1 - 0.18 10.5 0.1 0.29 9.8 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein p450 PF00067.22 ORY00895.1 - 6.3e-63 213.1 0.0 1.9e-61 208.2 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 DUF756 PF05506.12 ORY00895.1 - 0.12 13.3 0.1 0.29 12.1 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF756) MFS_1 PF07690.16 ORY00896.1 - 1.9e-34 119.2 26.9 2.4e-34 118.8 26.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily RseC_MucC PF04246.12 ORY00896.1 - 6.7 6.7 7.5 12 5.8 0.7 3.1 3 1 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC HET PF06985.11 ORY00898.1 - 1.5e-18 67.5 0.0 2.7e-18 66.7 0.0 1.4 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) F-box-like PF12937.7 ORY00900.1 - 9.2e-07 28.7 0.0 1.9e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY00900.1 - 0.00057 19.7 2.2 0.0013 18.5 0.1 2.4 2 0 0 2 2 2 1 F-box domain Ammonium_transp PF00909.21 ORY00901.1 - 1.8e-78 264.0 37.2 2e-78 263.9 37.2 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Phosphoesterase PF04185.14 ORY00906.1 - 1.6e-34 119.7 1.3 4.7e-34 118.1 1.3 1.7 1 1 0 1 1 1 1 Phosphoesterase family HIF-1a_CTAD PF08778.10 ORY00906.1 - 0.062 12.9 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 HIF-1 alpha C terminal transactivation domain WLM PF08325.10 ORY00906.1 - 0.086 12.9 0.0 13 5.8 0.0 2.3 2 0 0 2 2 2 0 WLM domain Glyco_transf_90 PF05686.12 ORY00907.1 - 8.8e-36 123.6 1.3 1.4e-35 123.0 1.3 1.3 1 1 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.6 ORY00907.1 - 0.014 15.8 0.0 0.026 14.9 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferases group 1 Thioredoxin PF00085.20 ORY00908.1 - 0.00012 22.0 0.1 0.00016 21.6 0.1 1.4 1 1 0 1 1 1 1 Thioredoxin HyaE PF07449.11 ORY00908.1 - 0.064 13.2 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Thioredoxin_2 PF13098.6 ORY00908.1 - 0.1 13.1 0.1 0.15 12.5 0.1 1.5 1 1 0 1 1 1 0 Thioredoxin-like domain DUF3176 PF11374.8 ORY00909.1 - 2e-23 82.6 2.7 4.6e-23 81.5 2.7 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) NmrA PF05368.13 ORY00910.1 - 1.4e-25 90.3 0.3 1.7e-25 90.0 0.3 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ORY00910.1 - 3e-09 37.0 1.0 5.2e-09 36.2 0.3 1.8 2 1 0 2 2 2 1 NAD(P)H-binding 3Beta_HSD PF01073.19 ORY00910.1 - 3.9e-06 26.1 0.2 5.8e-06 25.5 0.2 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 ORY00910.1 - 0.00043 20.2 0.0 0.00089 19.2 0.0 1.5 1 0 0 1 1 1 1 KR domain Semialdhyde_dh PF01118.24 ORY00910.1 - 0.0006 20.2 0.2 0.0018 18.7 0.1 1.8 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.21 ORY00910.1 - 0.0038 16.7 0.2 0.28 10.6 0.1 2.2 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.20 ORY00910.1 - 0.01 16.0 0.5 0.023 14.8 0.2 1.8 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus PrpR_N PF06506.11 ORY00910.1 - 0.011 15.3 0.3 2.1 7.9 0.1 2.4 1 1 1 2 2 2 0 Propionate catabolism activator IlvN PF07991.12 ORY00910.1 - 0.033 13.8 0.0 4.8 6.7 0.0 2.2 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain DXP_reductoisom PF02670.16 ORY00910.1 - 0.045 14.5 0.1 0.1 13.3 0.1 1.6 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mur_ligase PF01225.25 ORY00910.1 - 0.055 13.8 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 Mur ligase family, catalytic domain ColG_sub PF18496.1 ORY00910.1 - 0.055 13.6 0.1 0.28 11.4 0.0 2.0 2 0 0 2 2 2 0 Collagenase G catalytic helper subdomain Polysacc_synt_2 PF02719.15 ORY00910.1 - 0.064 12.4 0.0 0.094 11.8 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Phage_lysozyme2 PF18013.1 ORY00951.1 - 0.00099 19.1 0.4 0.0024 17.9 0.4 1.6 1 0 0 1 1 1 1 Phage tail lysozyme Glyco_hydro_39 PF01229.17 ORY00951.1 - 0.0061 15.2 0.2 0.0082 14.8 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 39 MFS_MOT1 PF16983.5 ORY00952.1 - 0.048 14.1 0.6 0.048 14.1 0.6 2.8 1 1 1 2 2 2 0 Molybdate transporter of MFS superfamily adh_short_C2 PF13561.6 ORY00953.1 - 5.7e-42 143.9 1.1 8.2e-42 143.4 1.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY00953.1 - 1.6e-32 112.6 0.8 2e-32 112.2 0.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORY00953.1 - 3.8e-07 30.2 0.8 6e-07 29.6 0.8 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 ORY00953.1 - 0.047 12.8 0.1 0.15 11.2 0.1 1.7 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein FMN_dh PF01070.18 ORY00954.1 - 6.3e-15 55.1 0.1 7.1e-15 54.9 0.1 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase STAT_alpha PF01017.20 ORY00955.1 - 3.7 7.4 11.4 2.7 7.8 0.7 2.2 2 0 0 2 2 2 0 STAT protein, all-alpha domain Peptidase_M50B PF13398.6 ORY00956.1 - 2.1e-60 203.8 19.1 2.7e-60 203.4 19.1 1.1 1 0 0 1 1 1 1 Peptidase M50B-like Peptidase_M50 PF02163.22 ORY00956.1 - 0.0062 15.8 0.2 0.012 14.9 0.2 1.4 1 0 0 1 1 1 1 Peptidase family M50 Patched PF02460.18 ORY00956.1 - 0.08 11.0 5.7 0.12 10.4 5.7 1.2 1 0 0 1 1 1 0 Patched family MLANA PF14991.6 ORY00956.1 - 0.4 11.0 4.5 0.15 12.4 0.8 2.1 1 1 1 2 2 2 0 Protein melan-A YlaC PF10777.9 ORY00956.1 - 2.8 7.7 5.2 0.38 10.6 0.4 1.9 2 0 0 2 2 2 0 Inner membrane protein YlaC Sugar_tr PF00083.24 ORY00957.1 - 1.8e-71 241.4 41.5 2.7e-37 128.7 10.0 3.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 ORY00957.1 - 1.8e-05 23.9 9.3 1.8e-05 23.9 9.3 3.0 2 1 1 3 3 3 1 Major Facilitator Superfamily DUF2530 PF10745.9 ORY00957.1 - 0.49 10.7 7.6 0.33 11.2 0.3 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2530) Saf_2TM PF18303.1 ORY00957.1 - 3.1 7.4 6.8 0.77 9.3 0.3 2.6 3 0 0 3 3 3 0 SAVED-fused 2TM effector domain MFS_1 PF07690.16 ORY00958.1 - 3.7e-24 85.3 30.3 1.7e-23 83.2 30.3 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily FAD_binding_3 PF01494.19 ORY00960.1 - 2.3e-15 56.7 0.1 5.9e-11 42.2 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 ORY00960.1 - 7.6e-06 26.1 0.3 2.2e-05 24.6 0.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ORY00960.1 - 0.00066 19.4 0.8 0.0018 17.9 0.3 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ORY00960.1 - 0.0008 18.7 0.1 0.0024 17.1 0.1 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 ORY00960.1 - 0.015 14.3 0.0 0.13 11.3 0.0 2.0 2 0 0 2 2 2 0 Squalene epoxidase HI0933_like PF03486.14 ORY00960.1 - 0.026 13.2 0.1 0.041 12.6 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Lycopene_cycl PF05834.12 ORY00960.1 - 0.04 13.0 0.0 0.32 10.0 0.0 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox PF00070.27 ORY00960.1 - 0.067 13.8 0.1 0.14 12.7 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ORY00960.1 - 0.086 11.9 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 ORY00960.1 - 0.21 10.8 0.2 0.41 9.9 0.2 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Zn_clus PF00172.18 ORY00963.1 - 1e-07 31.9 8.0 1.6e-07 31.3 8.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TauD PF02668.16 ORY00964.1 - 3e-46 158.4 0.1 4.2e-46 157.9 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CCSMST1 PF15013.6 ORY00964.1 - 0.073 13.2 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 CCSMST1 family MFS_1 PF07690.16 ORY00965.1 - 3.2e-18 65.8 14.8 4.2e-18 65.4 14.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily CBM_2 PF00553.19 ORY00965.1 - 0.18 12.2 1.4 0.36 11.2 1.4 1.4 1 0 0 1 1 1 0 Cellulose binding domain VKOR PF07884.14 ORY00965.1 - 8.1 6.6 13.5 1.1 9.5 2.1 2.5 2 0 0 2 2 2 0 Vitamin K epoxide reductase family CVNH PF08881.10 ORY00967.1 - 2.9e-08 34.3 0.7 4.8e-08 33.6 0.7 1.3 1 0 0 1 1 1 1 CVNH domain Rap1a PF18602.1 ORY00968.1 - 0.03 14.6 0.3 0.19 12.1 0.1 1.9 2 0 0 2 2 2 0 Rap1a immunity proteins Glyco_hydro_61 PF03443.14 ORY00969.1 - 5.8e-63 212.5 0.1 9.7e-63 211.8 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.18 ORY00969.1 - 2.2e-11 43.5 12.1 6e-11 42.1 12.1 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain GFO_IDH_MocA PF01408.22 ORY00970.1 - 2.7e-18 66.9 0.1 4.4e-18 66.3 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 ORY00970.1 - 0.0019 18.8 0.1 0.0031 18.2 0.1 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain OpuAC PF04069.12 ORY00970.1 - 0.06 12.9 0.2 0.33 10.5 0.1 2.2 2 1 1 3 3 3 0 Substrate binding domain of ABC-type glycine betaine transport system 3Beta_HSD PF01073.19 ORY00971.1 - 1.3e-33 116.2 0.0 1.7e-33 115.8 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 ORY00971.1 - 7.5e-22 78.0 0.0 9.5e-22 77.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ORY00971.1 - 8e-19 68.2 0.0 4.5e-15 55.9 0.0 2.3 2 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 ORY00971.1 - 3e-16 59.3 0.2 6.1e-16 58.4 0.2 1.5 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 ORY00971.1 - 8e-11 41.6 0.0 2.8e-10 39.8 0.0 1.7 1 1 1 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.10 ORY00971.1 - 3.5e-10 40.1 0.0 1.6e-09 37.9 0.0 2.0 2 0 0 2 2 2 1 KR domain RmlD_sub_bind PF04321.17 ORY00971.1 - 5.7e-08 32.2 0.0 7.8e-08 31.8 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 ORY00971.1 - 5e-05 23.3 0.0 8.2e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 ORY00971.1 - 0.11 12.7 0.0 0.93 9.8 0.0 2.2 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Glyco_hydro_106 PF17132.4 ORY00972.1 - 4.3e-15 55.1 2.1 6e-15 54.6 2.1 1.2 1 0 0 1 1 1 1 alpha-L-rhamnosidase BrkDBD PF09607.10 ORY00972.1 - 0.18 11.6 0.0 0.42 10.4 0.0 1.5 1 0 0 1 1 1 0 Brinker DNA-binding domain MFS_1 PF07690.16 ORY00973.1 - 6.4e-27 94.4 38.3 2.3e-20 72.8 16.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily F-box PF00646.33 ORY00974.1 - 5.6e-08 32.5 0.2 1.4e-07 31.2 0.2 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 ORY00974.1 - 6.9e-05 22.7 0.2 0.00027 20.8 0.0 2.1 2 0 0 2 2 2 1 F-box-like FAD_binding_4 PF01565.23 ORY00977.1 - 7.5e-28 97.0 0.0 1.2e-27 96.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.19 ORY00977.1 - 5.9e-07 29.4 0.0 1.2e-06 28.4 0.0 1.4 2 0 0 2 2 2 1 FAD linked oxidases, C-terminal domain CorA PF01544.18 ORY01030.1 - 2.1e-45 155.3 0.0 3.2e-45 154.7 0.0 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein MFS_1 PF07690.16 ORY01031.1 - 5.4e-33 114.4 27.3 5.4e-33 114.4 27.3 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily CLN3 PF02487.17 ORY01031.1 - 0.27 10.2 3.3 1.1 8.2 0.4 2.3 2 1 0 2 2 2 0 CLN3 protein Acyltransferase PF01553.21 ORY01033.1 - 6.8e-28 97.0 0.0 1.4e-27 95.9 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 ORY01033.1 - 2.9e-12 46.5 0.2 7.1e-12 45.2 0.2 1.7 1 0 0 1 1 1 1 Acyltransferase C-terminus Hep_59 PF07052.11 ORY01036.1 - 3e-16 60.1 1.3 5e-16 59.4 0.1 2.0 2 0 0 2 2 2 1 Hepatocellular carcinoma-associated antigen 59 PTR2 PF00854.21 ORY01038.1 - 1.4e-85 287.5 9.2 2.1e-85 287.0 9.2 1.2 1 0 0 1 1 1 1 POT family Helicase_C_2 PF13307.6 ORY01038.1 - 7.1e-53 179.3 0.0 1.5e-52 178.2 0.0 1.6 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 ORY01038.1 - 3e-37 127.9 0.0 9.4e-37 126.3 0.0 1.8 1 1 0 1 1 1 1 DEAD_2 ResIII PF04851.15 ORY01038.1 - 0.00085 19.4 0.0 0.51 10.3 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit SVIP PF15811.5 ORY01038.1 - 3 8.3 7.8 8.8 6.9 7.8 1.7 1 0 0 1 1 1 0 Small VCP/p97-interacting protein WD40 PF00400.32 ORY01039.1 - 4.9e-37 125.3 25.0 7.4e-05 23.5 1.6 10.8 11 0 0 11 11 11 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY01039.1 - 6.6e-19 68.0 1.2 8.7e-06 26.0 0.0 6.9 4 3 4 8 8 8 6 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 ORY01039.1 - 0.00029 21.2 14.6 0.1 13.1 0.0 6.7 6 1 1 7 7 7 1 PQQ-like domain WD40_like PF17005.5 ORY01039.1 - 0.0081 15.5 0.0 2.3 7.4 0.0 2.4 1 1 1 2 2 2 2 WD40-like domain Mcl1_mid PF12341.8 ORY01039.1 - 0.011 15.1 0.0 0.054 12.8 0.0 2.0 1 1 0 1 1 1 0 Minichromosome loss protein, Mcl1, middle region PQQ PF01011.21 ORY01039.1 - 0.019 14.9 0.3 11 6.2 0.0 3.8 4 0 0 4 4 4 0 PQQ enzyme repeat PD40 PF07676.12 ORY01039.1 - 0.026 14.5 0.7 61 3.7 0.0 4.5 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat SelA PF03841.13 ORY01039.1 - 0.24 10.3 0.0 0.35 9.8 0.0 1.1 1 0 0 1 1 1 0 L-seryl-tRNA selenium transferase PROL5-SMR PF15621.6 ORY01040.1 - 1.4 9.5 10.1 18 5.9 0.3 2.1 1 1 1 2 2 2 0 Proline-rich submaxillary gland androgen-regulated family Sugar_tr PF00083.24 ORY01044.1 - 1.5e-93 314.2 20.2 1.8e-93 313.9 20.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY01044.1 - 1.4e-18 66.9 33.1 2e-17 63.2 11.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2663 PF10864.8 ORY01044.1 - 1.5 9.2 3.7 0.78 10.2 0.2 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2663) DUF4246 PF14033.6 ORY01046.1 - 3.6e-171 570.3 0.0 4.1e-171 570.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) GST_N_3 PF13417.6 ORY01047.1 - 1.3e-15 57.6 0.0 2.2e-15 56.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 ORY01047.1 - 2e-15 56.9 0.0 3.7e-15 56.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 ORY01047.1 - 2.1e-14 53.5 0.0 4.2e-14 52.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 ORY01047.1 - 8.5e-11 42.0 0.0 1.7e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 ORY01047.1 - 8.9e-10 38.7 0.0 1.7e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 ORY01047.1 - 1.2e-05 25.2 0.0 2.2e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 ORY01047.1 - 0.00033 21.2 0.0 0.026 15.1 0.0 2.2 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 ORY01047.1 - 0.04 14.7 0.0 0.097 13.4 0.0 1.7 1 1 0 1 1 1 0 Glutathione S-transferase N-terminal domain CorA PF01544.18 ORY01048.1 - 2.4e-06 27.1 0.2 3.6e-06 26.5 0.2 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein baeRF_family10 PF18854.1 ORY01049.1 - 0.028 14.7 0.4 0.037 14.3 0.4 1.2 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 10 p450 PF00067.22 ORY01050.1 - 7.7e-62 209.5 0.0 1e-61 209.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 TRI12 PF06609.13 ORY01051.1 - 8.7e-61 206.1 19.2 1.1e-60 205.7 19.2 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 ORY01051.1 - 9.7e-20 70.8 37.9 9.7e-20 70.8 37.9 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY01051.1 - 5.1e-13 48.7 4.5 5.1e-13 48.7 4.5 2.6 2 0 0 2 2 2 2 Sugar (and other) transporter DUF3040 PF11239.8 ORY01051.1 - 0.22 11.8 0.0 0.22 11.8 0.0 4.8 4 1 0 5 5 5 0 Protein of unknown function (DUF3040) Gpr1_Fun34_YaaH PF01184.19 ORY01052.1 - 2.2e-30 105.8 22.2 2.7e-30 105.5 22.2 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Cu-oxidase_3 PF07732.15 ORY01053.1 - 6.1e-40 135.9 5.6 5.2e-39 132.9 1.1 2.8 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 ORY01053.1 - 1.2e-39 135.2 6.5 1.2e-36 125.5 0.2 4.2 3 2 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 ORY01053.1 - 2.2e-37 128.6 1.1 4.3e-37 127.7 0.3 2.0 2 0 0 2 2 2 1 Multicopper oxidase PAP_RNA-bind PF04926.15 ORY01053.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 Poly(A) polymerase predicted RNA binding domain Cupin_5 PF06172.11 ORY01054.1 - 2.1e-39 134.9 0.0 2.4e-39 134.7 0.0 1.0 1 0 0 1 1 1 1 Cupin superfamily (DUF985) S4 PF01479.25 ORY01056.1 - 1.8e-12 46.7 0.0 3.1e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.19 ORY01056.1 - 1.2e-10 42.2 0.1 1.7e-10 41.7 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain His_biosynth PF00977.21 ORY01057.1 - 1.2e-46 159.1 0.4 6.5e-46 156.6 0.4 2.2 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.28 ORY01057.1 - 5.3e-21 75.2 0.0 8.7e-21 74.5 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.19 ORY01057.1 - 1.6e-10 41.2 0.0 2.7e-07 30.6 0.0 2.2 2 0 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.14 ORY01057.1 - 5.5e-07 29.4 0.0 2.8e-06 27.1 0.0 1.9 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_C26 PF07722.13 ORY01057.1 - 0.024 14.4 0.3 0.3 10.8 0.3 2.2 1 1 0 1 1 1 0 Peptidase C26 Dus PF01207.17 ORY01057.1 - 0.078 12.1 0.1 0.23 10.5 0.0 1.7 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) SOR_SNZ PF01680.17 ORY01057.1 - 0.14 11.9 0.0 0.33 10.7 0.0 1.5 1 0 0 1 1 1 0 SOR/SNZ family RrnaAD PF00398.20 ORY01058.1 - 2.5e-65 220.2 0.0 4e-65 219.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 ORY01058.1 - 1e-06 29.4 0.0 2e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY01058.1 - 3.3e-05 24.4 0.0 8.5e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 ORY01058.1 - 0.00022 21.1 0.0 0.00036 20.3 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 ORY01058.1 - 0.001 18.6 0.0 0.0018 17.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 ORY01058.1 - 0.0012 18.7 0.0 0.0019 18.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY01058.1 - 0.0041 17.8 0.0 0.011 16.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_28 PF02636.17 ORY01058.1 - 0.051 13.2 0.0 0.089 12.4 0.0 1.4 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase AAA_lid_4 PF17864.1 ORY01058.1 - 0.074 12.8 0.1 0.17 11.7 0.1 1.5 1 0 0 1 1 1 0 RuvB AAA lid domain NodS PF05401.11 ORY01058.1 - 0.084 12.5 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Nodulation protein S (NodS) Cons_hypoth95 PF03602.15 ORY01058.1 - 0.13 11.9 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 AP_endonuc_2 PF01261.24 ORY01059.1 - 2.2e-30 105.7 0.0 3.1e-30 105.2 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel TPR_12 PF13424.6 ORY01060.1 - 2.8e-62 207.0 27.9 1.5e-15 57.3 0.1 8.1 3 2 6 9 9 9 9 Tetratricopeptide repeat TPR_10 PF13374.6 ORY01060.1 - 4e-62 204.6 25.6 1.9e-09 37.1 0.0 11.8 12 0 0 12 12 12 9 Tetratricopeptide repeat NB-ARC PF00931.22 ORY01060.1 - 4.1e-13 49.1 0.0 9.2e-13 48.0 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain TPR_16 PF13432.6 ORY01060.1 - 2.1e-12 47.5 21.6 0.0056 17.3 0.1 7.7 8 2 0 8 8 8 3 Tetratricopeptide repeat TPR_7 PF13176.6 ORY01060.1 - 2.3e-12 46.0 12.7 0.0097 15.9 0.1 8.2 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_MalT PF17874.1 ORY01060.1 - 3.4e-11 43.1 16.7 4.3e-05 23.0 0.0 3.5 1 1 1 3 3 3 2 MalT-like TPR region TPR_2 PF07719.17 ORY01060.1 - 2.3e-10 39.7 27.8 0.011 15.8 0.3 9.7 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_1 PF00515.28 ORY01060.1 - 6.1e-09 35.3 14.0 0.0086 15.9 0.1 7.7 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_8 PF13181.6 ORY01060.1 - 4e-08 32.8 15.5 0.00043 20.3 0.1 7.6 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_14 PF13428.6 ORY01060.1 - 4.1e-08 33.4 15.6 0.87 10.6 0.0 9.0 8 2 2 10 10 10 2 Tetratricopeptide repeat TPR_4 PF07721.14 ORY01060.1 - 4.8e-08 32.9 16.2 0.2 12.3 0.1 6.1 6 0 0 6 6 4 3 Tetratricopeptide repeat NACHT PF05729.12 ORY01060.1 - 2.6e-05 24.2 0.0 6.5e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 NACHT domain TPR_17 PF13431.6 ORY01060.1 - 2.7e-05 24.3 0.5 27 5.5 0.0 6.3 6 0 0 6 6 6 0 Tetratricopeptide repeat AAA_16 PF13191.6 ORY01060.1 - 0.00056 20.3 0.2 0.0042 17.5 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain TPR_19 PF14559.6 ORY01060.1 - 0.00063 20.2 13.8 5.2 7.7 0.0 6.3 3 2 2 7 7 7 2 Tetratricopeptide repeat GyrI-like PF06445.15 ORY01060.1 - 0.0038 17.5 0.0 0.0091 16.3 0.0 1.6 1 0 0 1 1 1 1 GyrI-like small molecule binding domain AAA_22 PF13401.6 ORY01060.1 - 0.05 13.9 0.0 0.24 11.6 0.0 2.2 1 0 0 1 1 1 0 AAA domain TPR_20 PF14561.6 ORY01060.1 - 0.22 11.9 7.6 7.6 6.9 0.0 5.6 6 0 0 6 6 5 0 Tetratricopeptide repeat AAA_25 PF13481.6 ORY01060.1 - 3.8 7.0 5.4 4.1 6.9 0.1 3.5 3 1 0 3 3 3 0 AAA domain FAD_binding_3 PF01494.19 ORY01061.1 - 0.00084 18.7 0.0 0.0013 18.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Zn_clus PF00172.18 ORY01062.1 - 2.1e-07 30.9 12.1 5.6e-07 29.6 12.1 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain IU_nuc_hydro PF01156.19 ORY01063.1 - 1.4e-13 51.1 0.0 1.8e-13 50.8 0.0 1.1 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Methyltransf_16 PF10294.9 ORY01105.1 - 4.2e-05 23.4 0.0 5.5e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase DUF3782 PF12644.7 ORY01105.1 - 0.061 13.5 0.0 5.8 7.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3782) Methyltransf_31 PF13847.6 ORY01106.1 - 7.4e-21 74.5 0.0 9.6e-21 74.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY01106.1 - 2.6e-08 34.5 0.0 5.2e-08 33.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY01106.1 - 7.6e-08 33.0 0.0 1.2e-07 32.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY01106.1 - 2e-07 31.0 0.0 3.7e-07 30.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY01106.1 - 7.6e-06 26.5 0.0 1.8e-05 25.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 ORY01106.1 - 0.00017 21.6 0.0 0.00024 21.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ORY01106.1 - 0.0048 16.4 0.0 0.0076 15.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 ORY01106.1 - 0.012 14.9 0.0 0.019 14.3 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase MetW PF07021.12 ORY01106.1 - 0.018 14.7 0.0 0.041 13.5 0.0 1.5 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW AdoMet_MTase PF07757.13 ORY01106.1 - 0.021 15.2 0.0 0.095 13.0 0.0 1.9 1 1 1 2 2 2 0 Predicted AdoMet-dependent methyltransferase NapE PF06796.11 ORY01107.1 - 1.2 8.7 4.4 0.33 10.5 1.0 1.8 2 0 0 2 2 2 0 Periplasmic nitrate reductase protein NapE KIX_2 PF16987.5 ORY01108.1 - 6.7e-08 32.4 0.5 6.7e-08 32.4 0.5 3.0 2 0 0 2 2 2 1 KIX domain MDM10 PF12519.8 ORY01108.1 - 0.096 11.5 11.6 0.25 10.2 11.6 1.6 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 PPL5 PF18168.1 ORY01108.1 - 0.43 9.8 8.9 0.87 8.8 8.9 1.4 1 0 0 1 1 1 0 Prim-pol family 5 SpoIIP PF07454.11 ORY01108.1 - 1.9 7.9 20.0 6.8 6.1 20.0 1.9 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) FTO_NTD PF12933.7 ORY01108.1 - 2 7.5 8.8 5.2 6.2 8.8 1.6 1 0 0 1 1 1 0 FTO catalytic domain SID-1_RNA_chan PF13965.6 ORY01108.1 - 2.2 6.6 3.5 3.7 5.9 3.5 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 CSRNP_N PF16019.5 ORY01108.1 - 3.1 7.7 21.3 0.21 11.5 14.5 2.5 2 0 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus CLN3 PF02487.17 ORY01108.1 - 3.7 6.5 10.2 9.6 5.1 10.2 1.6 1 0 0 1 1 1 0 CLN3 protein WD40 PF00400.32 ORY01110.1 - 3.6e-23 81.4 18.9 6.9e-06 26.7 0.2 7.1 6 0 0 6 6 6 6 WD domain, G-beta repeat F-box-like PF12937.7 ORY01110.1 - 2.6e-08 33.6 0.4 1.2e-07 31.5 0.1 2.2 2 0 0 2 2 2 1 F-box-like Nup160 PF11715.8 ORY01110.1 - 1.8e-05 23.6 0.3 0.0092 14.7 0.1 2.9 1 1 1 3 3 3 2 Nucleoporin Nup120/160 PQQ_3 PF13570.6 ORY01110.1 - 0.078 13.5 1.5 9.1 6.9 0.0 3.9 5 0 0 5 5 5 0 PQQ-like domain F-box PF00646.33 ORY01110.1 - 0.1 12.5 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 F-box domain bZIP_1 PF00170.21 ORY01112.1 - 0.0013 18.8 7.3 0.004 17.2 7.3 1.8 1 0 0 1 1 1 1 bZIP transcription factor Asparaginase PF00710.20 ORY01113.1 - 2e-26 92.8 0.0 2.9e-26 92.2 0.0 1.2 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 ORY01113.1 - 1.2e-12 48.0 0.0 2.7e-12 46.9 0.0 1.6 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain DEAD PF00270.29 ORY01114.1 - 1.1e-19 70.9 0.7 4.5e-19 68.9 0.0 2.3 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY01114.1 - 7.6e-19 68.1 0.0 2.1e-15 57.0 0.0 2.8 2 0 0 2 2 2 2 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 ORY01114.1 - 5.5e-06 27.0 0.3 1.9e-05 25.3 0.3 2.0 1 0 0 1 1 1 1 RecQ zinc-binding NPC1_N PF16414.5 ORY01114.1 - 0.099 12.2 0.4 0.26 10.8 0.2 1.7 2 0 0 2 2 2 0 Niemann-Pick C1 N terminus Bac_globin PF01152.21 ORY01114.1 - 0.14 12.3 0.0 2.1 8.5 0.0 2.5 2 0 0 2 2 2 0 Bacterial-like globin Ku_C PF03730.14 ORY01114.1 - 0.29 11.9 1.4 6.1 7.6 0.0 2.9 3 1 0 3 3 3 0 Ku70/Ku80 C-terminal arm Glyco_hydro_18 PF00704.28 ORY01115.1 - 0.14 11.9 0.0 0.14 11.8 0.0 1.0 1 0 0 1 1 1 0 Glycosyl hydrolases family 18 Lipase_3 PF01764.25 ORY01116.1 - 1.1e-13 51.2 0.0 2.3e-13 50.2 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) MFS_1 PF07690.16 ORY01117.1 - 3.5e-22 78.8 21.0 3.9e-22 78.7 21.0 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily ATP-synt_I PF03899.15 ORY01117.1 - 0.00047 20.5 2.4 1.1 9.7 0.0 3.3 2 2 1 3 3 3 2 ATP synthase I chain OATP PF03137.20 ORY01117.1 - 1.8 6.7 6.5 2.8 6.1 0.4 2.7 1 1 2 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Asp PF00026.23 ORY01118.1 - 9.5e-61 205.9 0.0 1.1e-60 205.7 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 ORY01118.1 - 9.2e-11 42.3 1.2 6.4e-08 33.0 0.8 2.8 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 ORY01118.1 - 0.007 17.0 0.2 11 6.7 0.0 3.2 2 1 0 2 2 2 2 Aspartyl protease N_BRCA1_IG PF16158.5 ORY01119.1 - 3.2e-28 98.4 0.0 1e-27 96.8 0.0 1.9 1 0 0 1 1 1 1 Ig-like domain from next to BRCA1 gene ZZ PF00569.17 ORY01119.1 - 8.1e-19 67.2 52.2 7.6e-07 28.8 7.2 4.4 4 0 0 4 4 4 4 Zinc finger, ZZ type CsgE PF10627.9 ORY01119.1 - 0.13 12.5 0.2 3.9 7.7 0.0 2.7 2 0 0 2 2 2 0 Curli assembly protein CsgE RRM_1 PF00076.22 ORY01120.1 - 1e-21 76.5 0.0 1.5e-12 47.1 0.0 3.7 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 ORY01120.1 - 2.1e-05 24.5 0.0 0.037 14.1 0.0 2.7 2 1 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 ORY01120.1 - 0.062 13.3 0.0 0.19 11.8 0.0 1.8 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Aldo_ket_red PF00248.21 ORY01121.1 - 5.5e-64 216.2 0.0 6.7e-64 215.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Zn_clus PF00172.18 ORY01122.1 - 5.7e-08 32.8 8.5 1.4e-07 31.5 8.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-met PF12874.7 ORY01122.1 - 0.072 13.5 0.2 0.22 11.9 0.2 1.9 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 ORY01122.1 - 0.3 12.1 1.6 1.3 10.0 1.6 2.2 1 0 0 1 1 1 0 C2H2-type zinc finger Zn_ribbon_recom PF13408.6 ORY01122.1 - 2.8 8.5 9.8 8.9 6.9 9.8 1.8 1 1 0 1 1 1 0 Recombinase zinc beta ribbon domain Fungal_trans PF04082.18 ORY01124.1 - 2.6e-11 43.1 0.0 6.3e-11 41.8 0.0 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY01124.1 - 1.5e-08 34.6 8.0 2.8e-08 33.7 8.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HET PF06985.11 ORY01169.1 - 3.2e-32 111.9 0.0 6.4e-32 110.9 0.0 1.5 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Abhydrolase_6 PF12697.7 ORY01171.1 - 3.9e-11 44.0 0.3 5.1e-11 43.6 0.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORY01171.1 - 4.8e-06 26.0 0.0 0.03 13.6 0.1 2.5 2 1 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ORY01171.1 - 0.00013 21.7 0.1 0.0016 18.1 0.1 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 ORY01171.1 - 0.00027 20.8 0.3 0.0031 17.4 0.3 2.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.13 ORY01171.1 - 0.0029 17.4 0.1 0.0044 16.8 0.1 1.2 1 0 0 1 1 1 1 PGAP1-like protein Lipase_3 PF01764.25 ORY01171.1 - 0.003 17.4 0.0 0.0043 16.9 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) LIDHydrolase PF10230.9 ORY01171.1 - 0.011 15.3 0.0 0.016 14.8 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Esterase PF00756.20 ORY01171.1 - 0.1 12.2 1.3 0.15 11.6 1.3 1.4 1 1 0 1 1 1 0 Putative esterase MAGE PF01454.19 ORY01172.1 - 5.2e-35 121.1 0.0 1.2e-34 119.9 0.0 1.7 1 0 0 1 1 1 1 MAGE family PHD PF00628.29 ORY01172.1 - 3.2e-10 39.7 8.8 7.3e-10 38.6 8.8 1.7 1 0 0 1 1 1 1 PHD-finger zf-CpG_bind_C PF12269.8 ORY01172.1 - 0.0072 16.1 0.6 0.019 14.8 0.6 1.6 1 0 0 1 1 1 1 CpG binding protein zinc finger C terminal domain PHB_acc_N PF07879.11 ORY01172.1 - 0.21 11.7 0.1 0.42 10.7 0.1 1.4 1 0 0 1 1 1 0 PHB/PHA accumulation regulator DNA-binding domain MAGE PF01454.19 ORY01173.1 - 4.3e-06 26.6 1.2 4.8e-06 26.4 0.0 1.6 2 0 0 2 2 2 1 MAGE family Pox_Ag35 PF03286.14 ORY01173.1 - 0.05 13.4 2.6 0.049 13.4 2.6 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Chalcone_2 PF16035.5 ORY01174.1 - 2.7e-63 213.5 0.0 4.8e-63 212.6 0.0 1.4 1 0 0 1 1 1 1 Chalcone isomerase like Chalcone_3 PF16036.5 ORY01174.1 - 0.019 15.1 0.1 0.12 12.5 0.0 2.2 2 0 0 2 2 2 0 Chalcone isomerase-like Nucleoporin2 PF04096.14 ORY01174.1 - 0.097 12.8 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 Nucleoporin autopeptidase Pam16 PF03656.13 ORY01175.1 - 8e-07 29.1 0.0 8.7e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 Pam16 DnaJ PF00226.31 ORY01175.1 - 0.00022 21.3 0.0 0.00033 20.7 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain Ribosomal_L24e PF01246.20 ORY01176.1 - 8.9e-32 109.1 4.5 1.7e-31 108.2 4.5 1.5 1 0 0 1 1 1 1 Ribosomal protein L24e GST_N_3 PF13417.6 ORY01177.1 - 2.6e-12 46.9 0.0 4.4e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 ORY01177.1 - 1.1e-05 25.6 0.0 2.2e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 ORY01177.1 - 0.00039 20.4 0.0 0.00078 19.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 ORY01177.1 - 0.06 13.7 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 ORY01177.1 - 0.22 12.3 0.0 1.3 9.8 0.0 2.0 1 1 0 1 1 1 0 Glutathione S-transferase N-terminal domain MFS_1 PF07690.16 ORY01178.1 - 0.035 13.0 0.0 0.035 13.0 0.0 1.0 1 0 0 1 1 1 0 Major Facilitator Superfamily Patatin PF01734.22 ORY01180.1 - 7.6e-21 75.2 0.3 1.7e-20 74.1 0.3 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase zf-RING_UBOX PF13445.6 ORY01180.1 - 5.3e-05 23.1 2.1 5.3e-05 23.1 2.1 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 ORY01180.1 - 0.00081 19.2 1.3 0.003 17.4 1.3 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORY01180.1 - 0.0049 16.7 4.5 0.015 15.1 4.5 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 ORY01180.1 - 0.009 16.2 7.9 0.009 16.2 7.9 2.6 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 ORY01180.1 - 0.027 14.4 1.7 0.081 12.8 1.7 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 ORY01180.1 - 0.027 14.4 7.6 0.074 13.0 7.6 1.8 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.6 ORY01180.1 - 0.044 14.1 9.5 0.061 13.7 6.2 2.7 1 1 1 2 2 2 0 Ring finger domain zf-C3HC4_3 PF13920.6 ORY01180.1 - 0.17 11.8 6.6 0.52 10.2 6.6 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) AAA_23 PF13476.6 ORY01181.1 - 0.00012 22.6 0.1 0.00065 20.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 ORY01181.1 - 0.0045 16.7 0.0 0.011 15.5 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 ORY01181.1 - 0.0048 17.4 1.8 0.0071 16.9 0.1 2.1 3 0 0 3 3 3 1 ABC transporter MMR_HSR1 PF01926.23 ORY01181.1 - 0.0092 16.1 0.0 0.039 14.0 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 ORY01181.1 - 0.014 15.6 0.1 0.069 13.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 ORY01181.1 - 0.02 14.8 0.0 0.036 14.0 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 ORY01181.1 - 0.02 15.2 0.0 0.059 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 ORY01181.1 - 0.037 13.9 0.0 0.72 9.8 0.0 2.3 2 0 0 2 2 2 0 NACHT domain RNA_helicase PF00910.22 ORY01181.1 - 0.086 13.2 0.1 3.7 8.0 0.0 2.6 2 0 0 2 2 2 0 RNA helicase DUF87 PF01935.17 ORY01181.1 - 0.12 12.4 0.1 0.29 11.2 0.1 1.6 1 0 0 1 1 1 0 Helicase HerA, central domain TMEM173 PF15009.6 ORY01184.1 - 0.05 12.7 2.7 0.082 12.1 2.2 1.5 1 1 1 2 2 2 0 Transmembrane protein 173 NACHT PF05729.12 ORY01187.1 - 1.3e-20 74.0 0.1 2.7e-20 73.0 0.1 1.5 1 0 0 1 1 1 1 NACHT domain HET PF06985.11 ORY01187.1 - 7.2e-12 45.9 14.4 1.3e-10 41.8 0.5 3.4 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) RNA_helicase PF00910.22 ORY01187.1 - 0.043 14.2 0.0 2 8.9 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_11 PF13086.6 ORY01187.1 - 0.17 11.6 0.0 0.3 10.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 ORY01187.1 - 0.21 11.9 0.0 0.41 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain WD40 PF00400.32 ORY01188.1 - 1.3e-20 73.4 2.2 9.3e-13 48.5 0.2 2.6 2 0 0 2 2 2 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY01188.1 - 6.7e-07 29.5 0.0 1.2e-05 25.5 0.0 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 ORY01188.1 - 0.037 13.0 0.5 0.31 10.0 0.2 2.0 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 ORY01188.1 - 0.21 9.8 0.0 0.31 9.3 0.0 1.1 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz Fungal_trans PF04082.18 ORY01191.1 - 3.8e-28 98.3 0.0 8.1e-28 97.2 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY01191.1 - 3.2e-09 36.7 13.0 5.6e-09 36.0 13.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ORC6 PF05460.13 ORY01191.1 - 0.66 9.2 4.9 8.3 5.6 0.4 2.2 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) DUF3720 PF12517.8 ORY01191.1 - 4.6 8.2 9.7 33 5.5 5.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3720) Abhydrolase_1 PF00561.20 ORY01192.1 - 7.2e-13 48.8 0.0 2e-12 47.3 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORY01192.1 - 9.4e-10 39.5 0.0 1.2e-09 39.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORY01192.1 - 1.6e-08 34.1 0.0 4.7e-08 32.6 0.0 1.8 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DUF2048 PF09752.9 ORY01192.1 - 0.0051 16.0 0.1 0.0093 15.1 0.1 1.4 1 0 0 1 1 1 1 Abhydrolase domain containing 18 Esterase PF00756.20 ORY01192.1 - 0.0067 16.1 0.0 0.01 15.5 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 ORY01192.1 - 0.011 15.3 0.0 1.5 8.2 0.0 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family Thioesterase PF00975.20 ORY01192.1 - 0.033 14.3 0.0 0.052 13.7 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain Palm_thioest PF02089.15 ORY01192.1 - 0.18 11.6 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 Palmitoyl protein thioesterase UIM PF02809.20 ORY01195.1 - 0.014 15.3 0.9 0.045 13.7 0.9 1.9 1 0 0 1 1 1 0 Ubiquitin interaction motif DUF676 PF05057.14 ORY01196.1 - 5.1e-06 26.2 0.0 5.9e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 ORY01196.1 - 0.047 13.4 0.1 0.096 12.4 0.0 1.4 1 1 0 1 1 1 0 PGAP1-like protein Abhydrolase_6 PF12697.7 ORY01196.1 - 0.11 13.0 0.0 0.13 12.8 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORY01196.1 - 0.13 11.5 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Sulfotransfer_4 PF17784.1 ORY01198.1 - 4.3e-16 59.4 0.3 1.4e-15 57.7 0.3 1.8 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 ORY01198.1 - 0.0056 17.1 0.0 0.0071 16.8 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase family SMI1_KNR4 PF09346.10 ORY01199.1 - 1.1e-06 29.1 0.0 1.7e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) SUKH_6 PF14568.6 ORY01199.1 - 3.8e-05 24.1 0.0 7.3e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 SMI1-KNR4 cell-wall SUKH_5 PF14567.6 ORY01199.1 - 0.00012 21.8 0.0 0.00023 20.9 0.0 1.5 1 0 0 1 1 1 1 SMI1-KNR4 cell-wall NUFIP1 PF10453.9 ORY01199.1 - 0.062 13.2 1.3 1 9.2 1.0 2.3 2 0 0 2 2 2 0 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) MARVEL PF01284.23 ORY01200.1 - 0.027 14.5 8.2 0.041 13.9 8.2 1.3 1 1 0 1 1 1 0 Membrane-associating domain UCR_UQCRX_QCR9 PF05365.12 ORY01200.1 - 0.056 13.4 0.6 0.18 11.8 0.6 1.9 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like UAA PF08449.11 ORY01201.1 - 5.8e-43 147.2 13.6 7.4e-43 146.9 13.6 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 ORY01201.1 - 1.3e-06 28.6 23.7 0.00081 19.6 8.3 3.5 3 1 0 3 3 3 2 EamA-like transporter family Nuc_sug_transp PF04142.15 ORY01201.1 - 0.00019 20.7 1.9 0.035 13.3 0.0 2.2 2 0 0 2 2 2 2 Nucleotide-sugar transporter KH_1 PF00013.29 ORY01203.1 - 2.9e-41 139.1 9.8 6.3e-18 64.4 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 ORY01203.1 - 5.5e-10 38.9 11.7 0.0042 16.9 1.6 3.5 3 1 0 3 3 3 3 KH domain KH_4 PF13083.6 ORY01203.1 - 1.8e-08 34.1 6.5 0.034 14.0 0.4 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 ORY01203.1 - 8.7e-05 22.5 6.5 0.13 12.3 0.1 3.4 3 0 0 3 3 3 2 NusA-like KH domain ADH_N PF08240.12 ORY01204.1 - 3.5e-32 110.5 0.7 5.5e-32 109.9 0.7 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORY01204.1 - 8.6e-13 48.4 0.0 1.3e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.6 ORY01204.1 - 0.0011 18.8 1.6 0.0018 18.2 0.1 2.3 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-associated Glu_dehyd_C PF16912.5 ORY01204.1 - 0.0039 16.7 0.0 0.0072 15.8 0.0 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus Yippee-Mis18 PF03226.14 ORY01205.1 - 3.6e-16 59.3 0.7 4e-16 59.1 0.7 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.8 ORY01205.1 - 0.0024 18.1 1.1 0.0033 17.6 1.1 1.3 1 0 0 1 1 1 1 C-terminal domain of RIG-I Zn_ribbon_SprT PF17283.2 ORY01205.1 - 0.026 14.4 2.7 2.3 8.2 0.2 2.3 2 0 0 2 2 2 0 SprT-like zinc ribbon domain zf-RRPl_C4 PF17026.5 ORY01205.1 - 0.029 14.5 2.0 0.15 12.1 1.5 2.0 1 1 1 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type Evr1_Alr PF04777.13 ORY01205.1 - 0.096 13.2 1.2 3.5 8.2 0.1 2.1 1 1 1 2 2 2 0 Erv1 / Alr family FAD_binding_3 PF01494.19 ORY01262.1 - 4.5e-17 62.3 1.4 2.7e-16 59.7 1.4 2.2 1 1 0 1 1 1 1 FAD binding domain SE PF08491.10 ORY01262.1 - 0.00026 20.1 0.0 0.0062 15.6 0.0 2.1 2 0 0 2 2 2 1 Squalene epoxidase NAD_binding_8 PF13450.6 ORY01262.1 - 0.011 15.9 0.4 0.032 14.5 0.4 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ORY01262.1 - 0.029 13.6 0.0 0.045 13.0 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORY01262.1 - 0.29 11.7 1.6 0.55 10.8 0.4 2.2 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Forkhead PF00250.18 ORY01263.1 - 0.039 14.2 0.0 0.088 13.1 0.0 1.6 1 0 0 1 1 1 0 Forkhead domain BUD22 PF09073.10 ORY01264.1 - 0.00078 18.9 6.4 0.001 18.5 6.4 1.1 1 0 0 1 1 1 1 BUD22 YL1 PF05764.13 ORY01264.1 - 0.0016 18.6 11.0 0.0022 18.1 11.0 1.1 1 0 0 1 1 1 1 YL1 nuclear protein RR_TM4-6 PF06459.12 ORY01264.1 - 0.1 12.4 1.8 0.15 11.8 1.8 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF913 PF06025.12 ORY01264.1 - 0.84 8.5 3.3 1.2 8.1 3.3 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) RNA_polI_A34 PF08208.11 ORY01264.1 - 1.6 8.7 16.1 2.6 8.1 16.1 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 SDA1 PF05285.12 ORY01264.1 - 1.8 7.9 17.2 2.6 7.4 17.2 1.1 1 0 0 1 1 1 0 SDA1 RRN3 PF05327.11 ORY01264.1 - 1.9 7.0 10.7 2.6 6.5 10.7 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 MAP17 PF15807.5 ORY01264.1 - 1.9 8.7 10.0 3.1 8.0 10.0 1.2 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 DUF3381 PF11861.8 ORY01264.1 - 2.1 8.1 14.5 3 7.6 14.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) Nop14 PF04147.12 ORY01264.1 - 2.2 6.4 15.6 3 5.9 15.6 1.0 1 0 0 1 1 1 0 Nop14-like family TFIIF_alpha PF05793.12 ORY01264.1 - 3.1 6.3 19.7 4.3 5.8 19.7 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) TLP-20 PF06088.11 ORY01264.1 - 6.9 6.5 7.7 11 5.9 7.7 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) His_Phos_1 PF00300.22 ORY01265.1 - 2.6e-09 37.1 0.0 1.4e-08 34.7 0.0 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Amidase PF01425.21 ORY01268.1 - 7.3e-18 64.8 0.0 9.6e-15 54.5 0.0 2.9 2 1 1 3 3 3 2 Amidase Forkhead PF00250.18 ORY01269.1 - 0.00014 22.0 0.0 0.00038 20.7 0.0 1.7 1 0 0 1 1 1 1 Forkhead domain bZIP_1 PF00170.21 ORY01269.1 - 0.27 11.3 3.6 0.55 10.4 2.3 2.2 2 0 0 2 2 2 0 bZIP transcription factor BRF1 PF07741.13 ORY01269.1 - 5.4 7.4 6.9 13 6.2 6.9 1.7 1 1 0 1 1 1 0 Brf1-like TBP-binding domain Sugarporin_N PF11471.8 ORY01269.1 - 5.9 6.9 6.0 0.39 10.7 0.3 2.0 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension bZIP_2 PF07716.15 ORY01269.1 - 9.9 6.3 6.9 9.3 6.4 4.8 2.1 2 0 0 2 2 2 0 Basic region leucine zipper FAA_hydrolase PF01557.18 ORY01270.1 - 2.8e-57 193.9 0.0 3.7e-57 193.5 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Ribosomal_L20 PF00453.18 ORY01271.1 - 0.028 14.5 0.0 0.071 13.2 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein L20 End3 PF12761.7 ORY01271.1 - 0.082 13.1 0.1 0.1 12.7 0.1 1.2 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 UvrD-helicase PF00580.21 ORY01273.1 - 2.3e-61 208.1 2.6 7.4e-60 203.1 2.6 2.3 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 ORY01273.1 - 5.8e-59 200.2 0.1 1e-56 192.8 0.0 2.9 2 1 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 ORY01273.1 - 1.7e-31 109.5 1.0 3.2e-31 108.6 0.1 2.0 2 0 0 2 2 2 1 AAA domain UvrD_C_2 PF13538.6 ORY01273.1 - 4.5e-14 52.0 0.0 3e-13 49.4 0.0 2.4 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 ORY01273.1 - 3.5e-08 33.4 0.3 1.7e-05 24.6 0.0 2.7 2 1 0 3 3 3 2 AAA domain Viral_helicase1 PF01443.18 ORY01273.1 - 0.00016 21.5 0.0 0.44 10.2 0.0 3.1 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.6 ORY01273.1 - 0.0045 16.8 0.3 0.025 14.4 0.3 2.3 1 1 0 1 1 1 1 AAA domain AAA_12 PF13087.6 ORY01273.1 - 0.012 15.3 0.0 0.049 13.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain NLPC_P60 PF00877.19 ORY01274.1 - 2.6e-09 37.0 0.1 4.1e-09 36.4 0.1 1.2 1 0 0 1 1 1 1 NlpC/P60 family GFA PF04828.14 ORY01276.1 - 3.4e-20 72.2 0.1 5.3e-20 71.5 0.1 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Rab_eff_C PF04698.12 ORY01276.1 - 0.013 13.9 2.5 0.015 13.6 2.5 1.1 1 0 0 1 1 1 0 Rab effector MyRIP/melanophilin C-terminus DUF4820 PF16091.5 ORY01276.1 - 0.19 11.1 2.6 0.23 10.8 2.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Epimerase PF01370.21 ORY01277.1 - 4.3e-10 39.5 0.2 1.8e-09 37.5 0.1 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 ORY01277.1 - 4.8e-09 35.6 0.0 6.4e-09 35.2 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 ORY01277.1 - 4.7e-08 33.1 0.0 5.7e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 ORY01277.1 - 0.064 12.3 0.0 0.085 11.9 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 ORY01277.1 - 0.13 11.7 0.3 0.87 8.9 0.2 2.2 2 1 0 2 2 2 0 GDP-mannose 4,6 dehydratase Ldh_1_N PF00056.23 ORY01277.1 - 0.18 11.9 0.0 0.28 11.3 0.0 1.3 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Cutinase PF01083.22 ORY01278.1 - 3.8e-46 157.3 2.9 4.5e-46 157.0 2.9 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 ORY01278.1 - 0.0027 17.3 1.2 0.0044 16.6 0.9 1.7 1 1 0 1 1 1 1 PE-PPE domain VirJ PF06057.11 ORY01278.1 - 0.0048 16.8 0.0 0.0079 16.1 0.0 1.2 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) DUF2974 PF11187.8 ORY01278.1 - 0.0063 16.1 0.1 0.026 14.1 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2974) Abhydrolase_2 PF02230.16 ORY01278.1 - 0.025 14.4 0.0 0.036 13.9 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Lipase_3 PF01764.25 ORY01278.1 - 0.086 12.7 0.2 0.12 12.2 0.2 1.2 1 0 0 1 1 1 0 Lipase (class 3) DUF4360 PF14273.6 ORY01280.1 - 7.5e-10 39.0 0.1 9.2e-10 38.7 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DNA_pack_C PF02499.15 ORY01280.1 - 0.024 13.6 0.1 0.027 13.4 0.1 1.0 1 0 0 1 1 1 0 Probable DNA packing protein, C-terminus Glyco_hydro_43 PF04616.14 ORY01281.1 - 3.3e-33 115.2 0.7 4.3e-33 114.9 0.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 FMO-like PF00743.19 ORY01282.1 - 1.8e-20 72.9 1.8 5.7e-17 61.3 0.2 3.0 1 1 1 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 ORY01282.1 - 1.8e-11 44.1 0.0 4.7e-11 42.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 ORY01282.1 - 6e-10 38.9 0.0 1.5e-08 34.3 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ORY01282.1 - 9.8e-09 34.9 0.0 4.7e-06 26.1 0.0 2.4 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ORY01282.1 - 1.2e-08 34.5 0.0 0.00012 21.4 0.0 3.9 3 1 1 4 4 4 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 ORY01282.1 - 7.8e-05 22.4 0.0 0.013 15.1 0.0 2.5 2 0 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.17 ORY01282.1 - 0.0014 17.9 0.7 0.0071 15.6 0.0 2.3 3 0 0 3 3 3 1 Thi4 family NAD_binding_9 PF13454.6 ORY01282.1 - 0.015 15.3 3.0 0.2 11.6 0.0 3.0 3 0 0 3 3 3 0 FAD-NAD(P)-binding GIDA PF01134.22 ORY01282.1 - 0.1 11.6 0.4 7.3 5.6 0.1 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 ORY01282.1 - 0.2 10.6 0.0 0.35 9.9 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein HI0933_like PF03486.14 ORY01282.1 - 0.22 10.2 0.5 0.59 8.8 0.1 1.9 2 0 0 2 2 2 0 HI0933-like protein Fe-ADH PF00465.19 ORY01283.1 - 4.1e-64 216.7 0.0 5.4e-64 216.3 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 ORY01283.1 - 7.5e-06 25.8 0.3 0.0084 15.8 0.1 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase ERbeta_N PF12497.8 ORY01283.1 - 0.1 12.4 0.0 0.29 11.0 0.0 1.7 1 0 0 1 1 1 0 Estrogen receptor beta Sugar_tr PF00083.24 ORY01285.1 - 2.4e-55 188.2 24.9 2.4e-25 89.3 0.0 3.0 1 1 2 3 3 3 3 Sugar (and other) transporter MFS_1 PF07690.16 ORY01285.1 - 8.1e-09 34.9 26.7 3.1e-07 29.7 10.2 3.3 1 1 2 3 3 3 3 Major Facilitator Superfamily Abhydrolase_3 PF07859.13 ORY01286.1 - 1.4e-18 67.5 0.0 2e-18 67.0 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S51 PF03575.17 ORY01286.1 - 0.062 12.9 0.0 0.097 12.3 0.0 1.2 1 0 0 1 1 1 0 Peptidase family S51 AMP-binding PF00501.28 ORY01287.1 - 3.2e-62 210.5 0.1 6e-61 206.3 0.1 2.4 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORY01287.1 - 8.7e-13 49.1 0.0 3.7e-12 47.0 0.0 2.1 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain Orthopox_A43R PF06517.11 ORY01287.1 - 0.15 11.9 0.1 0.25 11.1 0.1 1.3 1 0 0 1 1 1 0 Orthopoxvirus A43R protein Caps_synth PF05704.12 ORY01288.1 - 5e-13 49.1 0.2 1.1e-12 48.0 0.2 1.4 1 1 0 1 1 1 1 Capsular polysaccharide synthesis protein Gly_transf_sug PF04488.15 ORY01288.1 - 1.7e-05 25.3 0.0 3.9e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif FKBP_C PF00254.28 ORY01293.1 - 9.6e-33 112.4 0.0 1.2e-32 112.1 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase NAD_binding_10 PF13460.6 ORY01295.1 - 2.3e-09 37.4 0.3 3.5e-09 36.8 0.3 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 ORY01295.1 - 1.1e-08 35.0 0.5 2.1e-08 34.0 0.5 1.5 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 ORY01295.1 - 4.3e-07 29.6 0.7 1.3e-05 24.8 0.7 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.19 ORY01295.1 - 0.00022 20.6 0.2 0.00033 20.1 0.2 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 ORY01295.1 - 0.0031 16.9 0.4 0.0054 16.0 0.4 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.20 ORY01295.1 - 0.0072 16.4 0.4 0.011 15.8 0.4 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 ORY01295.1 - 0.0076 16.1 0.1 0.012 15.5 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.18 ORY01295.1 - 0.0095 16.2 1.1 0.021 15.1 0.6 1.8 2 0 0 2 2 2 1 TrkA-N domain Sacchrp_dh_NADP PF03435.18 ORY01295.1 - 0.015 15.6 0.3 0.029 14.6 0.3 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain ApbA PF02558.16 ORY01295.1 - 0.021 14.5 0.1 0.037 13.7 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3Beta_HSD PF01073.19 ORY01295.1 - 0.044 12.8 0.1 0.18 10.8 0.1 1.8 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family F-box PF00646.33 ORY01296.1 - 2.6e-06 27.2 1.1 7.8e-06 25.6 1.1 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 ORY01296.1 - 0.00057 19.7 0.7 0.0015 18.4 0.7 1.6 1 0 0 1 1 1 1 F-box-like Ras PF00071.22 ORY01328.1 - 3.4e-52 176.3 0.3 3.4e-51 173.1 0.3 1.9 1 1 0 1 1 1 1 Ras family Roc PF08477.13 ORY01328.1 - 1.4e-18 67.3 0.0 7.8e-17 61.6 0.0 2.3 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY01328.1 - 0.00035 20.1 0.0 0.0012 18.3 0.0 1.7 2 0 0 2 2 2 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 ORY01328.1 - 0.023 14.6 0.0 6.9 6.6 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase LcrG PF07216.12 ORY01328.1 - 0.028 14.4 0.2 0.048 13.6 0.2 1.4 1 0 0 1 1 1 0 LcrG protein FeoB_N PF02421.18 ORY01328.1 - 0.036 13.6 0.1 0.53 9.8 0.0 2.3 2 1 1 3 3 3 0 Ferrous iron transport protein B GTP_EFTU PF00009.27 ORY01328.1 - 0.039 13.5 0.1 3.7 7.0 0.0 2.9 2 1 1 3 3 3 0 Elongation factor Tu GTP binding domain Septin PF00735.18 ORY01328.1 - 0.047 13.0 0.1 0.097 11.9 0.0 1.5 2 0 0 2 2 2 0 Septin MMR_HSR1 PF01926.23 ORY01328.1 - 0.058 13.5 0.0 0.096 12.8 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.6 ORY01328.1 - 0.13 12.7 0.0 0.2 12.0 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 ORY01328.1 - 0.18 11.3 0.0 0.35 10.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AMP-binding PF00501.28 ORY01329.1 - 2.7e-77 260.2 0.0 3.4e-77 259.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 ORY01329.1 - 2.1e-18 66.0 0.9 5.4e-18 64.7 0.2 2.1 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 ORY01329.1 - 7.7e-16 58.8 0.0 1.6e-15 57.8 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Hydrolase PF00702.26 ORY01330.1 - 9.4e-09 35.9 0.0 1.3e-08 35.4 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 ORY01330.1 - 2.7e-07 30.8 0.0 4.6e-07 30.1 0.0 1.7 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ORY01330.1 - 0.00053 20.0 0.0 0.0013 18.7 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like CENP-T_C PF15511.6 ORY01331.1 - 8e-09 35.6 0.1 9.7e-09 35.3 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 ORY01331.1 - 2.4e-05 24.7 0.1 2.8e-05 24.5 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 ORY01331.1 - 7.2e-05 22.9 0.1 0.0001 22.4 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 ORY01331.1 - 0.0002 21.6 0.1 0.00035 20.8 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 ORY01331.1 - 0.0004 20.7 0.1 0.00056 20.2 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 ORY01331.1 - 0.0085 16.2 0.0 0.01 15.9 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 ORY01331.1 - 0.031 14.3 0.0 0.037 14.0 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 ORY01331.1 - 0.052 13.3 0.2 0.064 13.0 0.2 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) HIGH_NTase1_ass PF16581.5 ORY01331.1 - 0.11 12.5 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 Cytidyltransferase-related C-terminal region Histone PF00125.24 ORY01332.1 - 4e-52 176.0 2.5 4.5e-52 175.9 2.5 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 ORY01332.1 - 6e-06 26.5 0.0 9e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein PAF PF15715.5 ORY01332.1 - 4e-05 24.2 1.2 4.7e-05 24.0 1.2 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-T_C PF15511.6 ORY01332.1 - 4.3e-05 23.6 0.3 7.9e-05 22.7 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 ORY01332.1 - 0.0038 17.5 0.4 0.0065 16.7 0.0 1.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 ORY01332.1 - 0.028 14.5 0.2 0.048 13.7 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit AhpC-TSA PF00578.21 ORY01333.1 - 0.0015 18.4 0.0 0.0023 17.8 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family AhpC-TSA_2 PF13911.6 ORY01333.1 - 0.0021 18.1 0.0 0.0035 17.4 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme Exo5 PF09810.9 ORY01334.1 - 1.8e-122 409.4 0.0 2.4e-122 409.0 0.0 1.2 1 0 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease PDDEXK_1 PF12705.7 ORY01334.1 - 7.1e-05 22.8 0.0 0.38 10.6 0.0 2.5 2 1 0 2 2 2 2 PD-(D/E)XK nuclease superfamily Glyco_hydro_43 PF04616.14 ORY01335.1 - 0.00068 19.0 0.3 0.0019 17.6 0.3 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 RED_N PF07808.13 ORY01336.1 - 4.5e-06 26.4 0.2 4.5e-06 26.4 0.2 2.1 2 0 0 2 2 2 1 RED-like protein N-terminal region Proteasome PF00227.26 ORY01337.1 - 9.5e-47 158.9 0.2 1.1e-46 158.7 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit CorA PF01544.18 ORY01338.1 - 2.6e-11 43.4 0.0 4.3e-11 42.7 0.0 1.4 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF1330 PF07045.11 ORY01338.1 - 0.084 13.2 0.4 2.9 8.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1330) ATP-synt_F6 PF05511.11 ORY01338.1 - 0.086 13.3 0.0 0.32 11.4 0.0 1.9 1 0 0 1 1 1 0 Mitochondrial ATP synthase coupling factor 6 TFIID_20kDa PF03847.13 ORY01339.1 - 3.4e-23 81.9 0.2 5.3e-23 81.3 0.2 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A MgsA_C PF12002.8 ORY01339.1 - 0.048 13.6 4.2 0.12 12.3 4.2 1.7 1 0 0 1 1 1 0 MgsA AAA+ ATPase C terminal UPF0242 PF06785.11 ORY01339.1 - 0.25 11.4 19.4 0.64 10.1 19.4 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus UvrD_C PF13361.6 ORY01339.1 - 2 7.7 11.5 3.6 6.9 11.0 1.6 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain V_ATPase_I PF01496.19 ORY01339.1 - 2.7 5.8 15.9 6.2 4.6 15.9 1.5 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Seryl_tRNA_N PF02403.22 ORY01339.1 - 5.4 7.3 15.6 13 6.0 15.6 1.7 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain MRP-S27 PF10037.9 ORY01339.1 - 6.6 5.5 16.5 11 4.8 15.8 1.6 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S27 Exo_endo_phos PF03372.23 ORY01340.1 - 1.8e-14 53.9 0.0 3.1e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family WD40 PF00400.32 ORY01341.1 - 4e-62 204.7 14.5 1.5e-11 44.6 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY01341.1 - 7.9e-21 74.2 0.2 0.0065 16.7 0.0 6.1 3 2 3 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ORY01341.1 - 2.6e-07 30.7 0.0 0.017 15.0 0.0 3.6 2 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 ORY01341.1 - 6.7e-07 28.6 0.1 0.47 9.4 0.0 4.4 1 1 2 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 ORY01341.1 - 1.2e-06 27.5 1.3 0.038 12.6 0.7 3.8 2 2 0 2 2 2 2 Nucleoporin Nup120/160 WD40_like PF17005.5 ORY01341.1 - 1.8e-05 24.3 0.0 0.00021 20.7 0.0 2.5 3 0 0 3 3 3 1 WD40-like domain PD40 PF07676.12 ORY01341.1 - 0.00017 21.4 0.6 19 5.3 0.1 4.5 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat DUF1513 PF07433.11 ORY01341.1 - 0.0032 16.6 0.2 0.84 8.7 0.0 3.3 1 1 2 3 3 3 1 Protein of unknown function (DUF1513) Frtz PF11768.8 ORY01341.1 - 0.0038 15.6 0.0 0.012 13.9 0.0 1.7 3 0 0 3 3 3 1 WD repeat-containing and planar cell polarity effector protein Fritz VID27 PF08553.10 ORY01341.1 - 0.032 13.3 0.0 3.9 6.4 0.0 3.1 2 1 2 4 4 4 0 VID27 C-terminal WD40-like domain Nucleoporin_N PF08801.11 ORY01341.1 - 0.035 12.9 0.3 38 2.9 0.0 3.9 2 2 2 4 4 4 0 Nup133 N terminal like PALB2_WD40 PF16756.5 ORY01341.1 - 1.5 7.7 3.4 3.6 6.4 0.1 2.7 3 1 1 4 4 4 0 Partner and localizer of BRCA2 WD40 domain polyprenyl_synt PF00348.17 ORY01342.1 - 1.8e-71 240.2 0.0 3.3e-71 239.3 0.0 1.4 1 1 0 1 1 1 1 Polyprenyl synthetase HEPPP_synt_1 PF07307.11 ORY01342.1 - 0.12 12.0 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 DUF3659 PF12396.8 ORY01342.1 - 0.17 11.9 0.1 6 6.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3659) Vma12 PF11712.8 ORY01343.1 - 9.9e-46 155.3 0.0 1.4e-45 154.8 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF4386 PF14329.6 ORY01343.1 - 0.081 12.8 0.0 0.11 12.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4386) Vac14_Fig4_bd PF11916.8 ORY01344.1 - 1.5e-81 272.3 6.8 1.5e-81 272.3 6.8 2.1 2 0 0 2 2 2 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 ORY01344.1 - 2.6e-48 162.6 0.2 1.1e-42 144.6 0.0 4.5 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 ORY01344.1 - 4.1e-11 43.1 3.1 0.0096 16.4 0.0 6.4 6 0 0 6 6 6 2 HEAT-like repeat HEAT PF02985.22 ORY01344.1 - 1.4e-08 34.2 3.8 0.001 19.1 0.0 6.4 6 0 0 6 6 6 1 HEAT repeat HEAT_2 PF13646.6 ORY01344.1 - 1.2e-07 32.0 1.0 0.18 12.2 0.0 5.3 5 0 0 5 5 5 2 HEAT repeats Cnd1 PF12717.7 ORY01344.1 - 1.9e-07 31.2 2.4 0.015 15.4 0.4 4.1 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Arm PF00514.23 ORY01344.1 - 4.4e-05 23.4 0.2 12 6.1 0.0 5.7 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat DENN PF02141.21 ORY01345.1 - 7.5e-05 22.8 0.1 0.0013 18.7 0.1 2.3 1 1 0 1 1 1 1 DENN (AEX-3) domain SPA PF08616.10 ORY01345.1 - 0.0072 16.3 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 Stabilization of polarity axis MCM PF00493.23 ORY01346.1 - 2.3e-102 340.9 0.0 3.4e-102 340.3 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 ORY01346.1 - 2.7e-39 133.9 0.1 4.8e-39 133.1 0.1 1.4 1 0 0 1 1 1 1 MCM OB domain MCM2_N PF12619.8 ORY01346.1 - 1.1e-28 100.5 30.1 1.1e-28 100.5 30.1 2.1 3 0 0 3 3 2 1 Mini-chromosome maintenance protein 2 MCM_lid PF17855.1 ORY01346.1 - 1.3e-23 83.2 0.4 3.3e-23 81.9 0.4 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 ORY01346.1 - 2.5e-14 53.7 0.1 6e-14 52.5 0.1 1.6 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 ORY01346.1 - 2.4e-08 33.6 0.1 2.2e-06 27.2 0.0 2.5 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 ORY01346.1 - 3.7e-06 27.0 0.0 7.9e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 ORY01346.1 - 0.00013 21.8 0.0 0.00054 19.8 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 ORY01346.1 - 0.014 15.1 0.1 0.077 12.7 0.1 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_30 PF13604.6 ORY01346.1 - 0.074 12.8 0.1 0.14 11.8 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 ORY01346.1 - 0.1 13.0 0.0 0.29 11.5 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) zf-UBR PF02207.20 ORY01347.1 - 8.3e-14 51.5 3.5 8.3e-14 51.5 3.5 2.8 3 0 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) NIF3 PF01784.18 ORY01348.1 - 5.2e-58 196.6 0.0 6.9e-58 196.2 0.0 1.1 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) BolA PF01722.18 ORY01349.1 - 6.7e-19 68.0 0.1 6.4e-18 64.8 0.0 2.2 2 1 0 2 2 2 1 BolA-like protein COG6 PF06419.11 ORY01350.1 - 7.6e-218 724.7 7.6 8.7e-218 724.6 7.6 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 MNE1 PF13762.6 ORY01350.1 - 0.014 15.4 0.0 0.03 14.3 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial splicing apparatus component COG2 PF06148.11 ORY01350.1 - 0.061 13.4 0.5 4.2 7.5 0.3 3.2 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Peptidase_C12 PF01088.21 ORY01350.1 - 0.083 12.6 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase, family 1 Muted PF14942.6 ORY01350.1 - 5.6 7.3 8.2 2.2 8.6 1.5 3.4 2 2 1 3 3 3 0 Organelle biogenesis, Muted-like protein APG9 PF04109.16 ORY01351.1 - 4.9e-181 602.9 12.8 5.8e-181 602.7 12.8 1.0 1 0 0 1 1 1 1 Autophagy protein Apg9 Ribosomal_L7Ae PF01248.26 ORY01352.1 - 2.4e-24 84.9 0.0 2.8e-24 84.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Ribosomal_L16 PF00252.18 ORY01353.1 - 5.5e-45 152.6 0.1 7.3e-45 152.2 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e DUF1490 PF07371.12 ORY01353.1 - 0.15 12.1 0.0 0.32 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1490) Kinesin PF00225.23 ORY01355.1 - 1.2e-83 280.9 0.8 1.2e-83 280.9 0.8 1.5 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 ORY01355.1 - 2.8e-19 69.5 0.0 5.6e-19 68.5 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding HHH PF00633.23 ORY01355.1 - 7.9e-06 25.5 0.5 0.071 13.0 0.0 2.7 2 0 0 2 2 2 2 Helix-hairpin-helix motif HHH_5 PF14520.6 ORY01355.1 - 0.0064 17.1 5.0 0.74 10.5 0.4 3.0 2 1 1 3 3 3 2 Helix-hairpin-helix domain Trimer_CC PF08954.11 ORY01355.1 - 0.09 12.4 1.9 0.13 11.9 0.1 2.2 2 0 0 2 2 2 0 Trimerisation motif CdvA PF18822.1 ORY01355.1 - 3.2 7.6 8.7 0.33 10.8 3.0 2.2 2 0 0 2 2 2 0 CdvA-like coiled-coil domain DUF3796 PF12676.7 ORY01356.1 - 1 9.8 2.7 1.5 9.3 2.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3796) zf-C2H2 PF00096.26 ORY01357.1 - 0.00017 21.9 13.3 0.04 14.4 2.9 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY01357.1 - 0.00028 21.2 6.1 0.00031 21.0 3.8 2.4 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORY01357.1 - 0.02 15.7 12.6 0.082 13.8 2.9 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger TylF PF05711.11 ORY01357.1 - 0.15 11.3 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 Macrocin-O-methyltransferase (TylF) Sec23_trunk PF04811.15 ORY01358.1 - 3.6e-70 236.3 0.0 1.2e-69 234.6 0.0 1.8 2 0 0 2 2 2 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 ORY01358.1 - 7.4e-22 77.1 0.0 2.2e-21 75.6 0.0 1.8 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 ORY01358.1 - 2.4e-17 63.5 0.0 5.2e-17 62.4 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 ORY01358.1 - 2.7e-17 62.5 4.3 5e-17 61.7 4.3 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 ORY01358.1 - 1e-08 34.9 0.0 2.1e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat Vps36-NZF-N PF16988.5 ORY01358.1 - 0.013 14.9 0.1 0.028 13.8 0.1 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Pil1 PF13805.6 ORY01360.1 - 1.7e-99 332.6 7.9 2e-99 332.4 7.9 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 Catalase PF00199.19 ORY01363.1 - 1e-161 538.4 0.0 1.3e-161 538.0 0.0 1.2 1 0 0 1 1 1 1 Catalase Catalase_C PF18011.1 ORY01363.1 - 1.1e-39 135.5 0.3 1.7e-39 134.9 0.3 1.3 1 0 0 1 1 1 1 C-terminal domain found in long catalases Catalase-rel PF06628.12 ORY01363.1 - 1.2e-13 51.0 0.0 2.2e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 Catalase-related immune-responsive Methyltransf_23 PF13489.6 ORY01364.1 - 2.3e-14 53.5 0.0 3.4e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY01364.1 - 1.5e-11 44.9 0.0 2.5e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY01364.1 - 6.4e-11 42.3 0.0 8.6e-11 41.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY01364.1 - 3.3e-10 40.5 0.0 5.8e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY01364.1 - 3.8e-10 40.4 0.0 6.5e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 ORY01364.1 - 0.00022 21.4 0.0 0.00035 20.7 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.14 ORY01364.1 - 0.00043 19.9 0.0 0.00076 19.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.18 ORY01364.1 - 0.00052 19.4 0.0 0.0008 18.8 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_4 PF02390.17 ORY01364.1 - 0.00066 19.2 0.0 0.0016 17.9 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase Ubie_methyltran PF01209.18 ORY01364.1 - 0.0018 17.7 0.0 0.0044 16.4 0.0 1.6 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 ORY01364.1 - 0.19 11.7 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain XFP_N PF09364.10 ORY01365.1 - 2.6e-173 575.9 0.0 3.9e-173 575.4 0.0 1.2 1 0 0 1 1 1 1 XFP N-terminal domain XFP_C PF09363.10 ORY01365.1 - 5.6e-88 293.7 0.0 8.9e-88 293.0 0.0 1.3 1 0 0 1 1 1 1 XFP C-terminal domain XFP PF03894.15 ORY01365.1 - 2.5e-81 271.6 0.0 3.9e-81 271.0 0.0 1.3 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase PIG-L PF02585.17 ORY01366.1 - 0.0017 19.0 1.2 0.04 14.5 1.2 2.4 1 1 0 1 1 1 1 GlcNAc-PI de-N-acetylase dCache_2 PF08269.11 ORY01416.1 - 0.84 8.7 0.0 0.84 8.7 0.0 3.9 2 1 1 3 3 3 0 Cache domain Hepar_II_III PF07940.13 ORY01417.1 - 0.036 13.7 0.0 0.043 13.4 0.0 1.2 1 0 0 1 1 1 0 Heparinase II/III-like protein Otopetrin PF03189.13 ORY01418.1 - 0.036 12.9 3.2 0.059 12.2 3.2 1.2 1 0 0 1 1 1 0 Otopetrin Abhydrolase_3 PF07859.13 ORY01419.1 - 6e-28 98.2 0.0 7.5e-28 97.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 ORY01419.1 - 0.0038 16.1 0.0 0.0053 15.7 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Glyco_hydro_7 PF00840.20 ORY01420.1 - 3.3e-166 553.4 13.1 9e-166 551.9 13.1 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 7 FlaE PF07559.14 ORY01420.1 - 0.058 14.0 0.0 0.14 12.7 0.0 1.7 2 0 0 2 2 2 0 Flagellar basal body protein FlaE Phytase PF02333.15 ORY01421.1 - 7.8e-70 235.7 0.2 1.5e-69 234.8 0.2 1.3 1 0 0 1 1 1 1 Phytase EGF_2 PF07974.13 ORY01421.1 - 1.5e-05 25.2 39.0 0.0055 17.1 13.9 2.6 2 0 0 2 2 2 2 EGF-like domain Metallophos PF00149.28 ORY01422.1 - 2.2e-10 41.4 0.2 3.4e-10 40.8 0.2 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 ORY01422.1 - 0.00014 22.1 0.1 0.001 19.3 0.1 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain TspO_MBR PF03073.15 ORY01423.1 - 0.0063 16.6 0.3 0.0063 16.6 0.3 2.5 2 0 0 2 2 2 1 TspO/MBR family 7tm_7 PF08395.12 ORY01423.1 - 1.5 7.9 6.4 3.7 6.7 0.9 2.1 2 0 0 2 2 2 0 7tm Chemosensory receptor Lipase_3 PF01764.25 ORY01424.1 - 2.2e-06 27.6 0.0 4e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_3 PF07859.13 ORY01424.1 - 0.0063 16.4 0.0 0.0096 15.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold AIRS PF00586.24 ORY01424.1 - 0.048 14.3 0.1 0.092 13.4 0.1 1.5 1 0 0 1 1 1 0 AIR synthase related protein, N-terminal domain DUF2974 PF11187.8 ORY01424.1 - 0.1 12.1 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_2 PF02230.16 ORY01424.1 - 0.12 12.2 0.1 0.18 11.5 0.1 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase p450 PF00067.22 ORY01425.1 - 1.2e-62 212.1 0.0 1.6e-62 211.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 SBF PF01758.16 ORY01426.1 - 0.0059 16.3 3.6 0.0059 16.3 3.6 1.9 1 1 1 2 2 2 1 Sodium Bile acid symporter family ThrE PF06738.12 ORY01426.1 - 0.38 10.1 5.2 0.85 8.9 5.2 1.5 1 0 0 1 1 1 0 Putative threonine/serine exporter DUF3671 PF12420.8 ORY01426.1 - 0.53 10.4 9.4 9.5 6.3 2.0 3.2 2 1 1 3 3 3 0 Protein of unknown function FAD_binding_8 PF08022.12 ORY01428.1 - 2.9e-19 69.1 0.0 6.7e-19 68.0 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 ORY01428.1 - 6.5e-12 45.8 0.0 1.8e-11 44.4 0.0 1.8 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 ORY01428.1 - 1.4e-11 44.6 7.8 2e-11 44.1 6.8 1.8 1 1 0 1 1 1 1 Ferric reductase like transmembrane component ZZ PF00569.17 ORY01429.1 - 0.0031 17.3 6.9 0.0072 16.1 6.9 1.6 1 0 0 1 1 1 1 Zinc finger, ZZ type CTP_transf_like PF01467.26 ORY01430.1 - 0.0036 17.5 0.4 0.016 15.4 0.4 2.0 1 1 0 1 1 1 1 Cytidylyltransferase-like cobW PF02492.19 ORY01431.1 - 2.3e-27 95.7 4.4 1e-14 54.5 0.6 2.2 1 1 1 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 ORY01431.1 - 9.1e-18 64.0 0.0 5.8e-13 48.6 0.0 2.5 2 0 0 2 2 2 2 Cobalamin synthesis protein cobW C-terminal domain COPR5 PF15340.6 ORY01431.1 - 0.036 14.7 0.1 0.13 12.9 0.1 1.9 1 0 0 1 1 1 0 Cooperator of PRMT5 family FAA_hydrolase PF01557.18 ORY01432.1 - 1.9e-52 178.1 0.0 2.6e-52 177.7 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 ORY01432.1 - 9.4e-19 67.6 0.0 6.1e-18 65.0 0.0 2.1 2 0 0 2 2 2 1 Fumarylacetoacetase N-terminal zf-rbx1 PF12678.7 ORY01433.1 - 3.8e-08 33.5 0.6 6.3e-08 32.8 0.6 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 ORY01433.1 - 6.8e-08 32.7 0.3 2.2e-07 31.1 0.3 1.8 1 1 0 1 1 1 1 Ring finger domain zf-ANAPC11 PF12861.7 ORY01433.1 - 1.2e-06 28.5 0.4 1.9e-06 27.8 0.4 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 ORY01433.1 - 2.5e-06 27.4 0.9 4.8e-06 26.5 0.9 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 ORY01433.1 - 0.00025 20.9 0.7 0.00046 20.1 0.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 ORY01433.1 - 0.0012 18.7 0.5 0.013 15.3 0.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORY01433.1 - 0.0021 17.9 0.1 0.006 16.4 0.1 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 ORY01433.1 - 0.0086 16.2 0.1 0.018 15.2 0.1 1.5 1 0 0 1 1 1 1 FANCL C-terminal domain zf-C3HC4_4 PF15227.6 ORY01433.1 - 0.011 15.9 0.9 0.02 15.0 0.1 1.8 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING AAL_decarboxy PF03306.13 ORY01434.1 - 2.3e-28 99.0 0.0 7.5e-26 90.8 0.0 2.0 1 1 0 1 1 1 1 Alpha-acetolactate decarboxylase HET PF06985.11 ORY01435.1 - 1.2e-26 93.8 0.0 1.4e-26 93.6 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Clr2 PF10383.9 ORY01435.1 - 0.019 15.8 0.0 0.079 13.7 0.0 1.7 1 1 1 2 2 2 0 Transcription-silencing protein Clr2 DUF4131 PF13567.6 ORY01436.1 - 0.15 11.7 1.4 2 8.1 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Amidohydro_3 PF07969.11 ORY01437.1 - 5.2e-71 240.5 1.4 5.9e-71 240.4 1.4 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 ORY01437.1 - 8.8e-11 41.7 2.0 2.4e-07 30.4 0.6 2.7 2 1 0 2 2 2 2 Amidohydrolase family YbjQ_1 PF01906.17 ORY01439.1 - 2.3e-20 73.2 1.1 2.9e-20 72.9 1.1 1.1 1 0 0 1 1 1 1 Putative heavy-metal-binding DUF5507 PF17612.2 ORY01439.1 - 0.17 11.6 0.0 0.22 11.2 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5507) DIOX_N PF14226.6 ORY01440.1 - 6.9e-19 68.7 0.0 1.1e-18 68.1 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 ORY01440.1 - 2.8e-17 63.0 0.0 9.9e-17 61.3 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Transp_cyt_pur PF02133.15 ORY01441.1 - 2.8e-33 115.4 15.5 6.5e-25 87.8 8.2 2.6 1 1 2 3 3 3 2 Permease for cytosine/purines, uracil, thiamine, allantoin Peptidase_S10 PF00450.22 ORY01442.1 - 1.5e-95 321.1 2.7 2e-95 320.7 2.7 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_1 PF00561.20 ORY01443.1 - 2e-10 40.8 0.1 9.6e-07 28.7 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORY01443.1 - 4e-08 34.1 2.6 5.7e-08 33.6 2.6 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORY01443.1 - 1.1e-05 24.8 0.1 0.00021 20.6 0.1 2.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 UPF0227 PF05728.12 ORY01443.1 - 0.072 13.0 0.0 0.27 11.1 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) DUF2852 PF11014.8 ORY01444.1 - 0.0025 17.9 0.4 2.1 8.5 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF2852) Peptidase_M24 PF00557.24 ORY01445.1 - 1e-37 129.9 0.7 1.4e-37 129.4 0.7 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Fungal_trans PF04082.18 ORY01446.1 - 0.021 13.8 0.0 0.046 12.7 0.0 1.5 1 0 0 1 1 1 0 Fungal specific transcription factor domain DUF3176 PF11374.8 ORY01447.1 - 0.0084 16.3 0.2 0.014 15.6 0.1 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3176) TRAPPC10 PF12584.8 ORY01488.1 - 6.1e-34 117.0 0.0 1.1e-33 116.2 0.0 1.4 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 TPR_9 PF13371.6 ORY01488.1 - 0.026 14.7 1.4 7 6.9 0.7 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat SNAP PF14938.6 ORY01488.1 - 0.15 11.5 0.2 0.25 10.7 0.2 1.3 1 0 0 1 1 1 0 Soluble NSF attachment protein, SNAP Rep_fac_C PF08542.11 ORY01490.1 - 1.5e-23 83.0 0.1 5.8e-23 81.1 0.0 2.0 3 0 0 3 3 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 ORY01490.1 - 2e-12 47.2 0.0 9.8e-09 35.2 0.0 2.3 1 1 1 2 2 2 2 DNA polymerase III, delta subunit AAA PF00004.29 ORY01490.1 - 1.4e-10 41.7 0.0 2.2e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 ORY01490.1 - 7.9e-07 29.2 0.0 1.7e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ORY01490.1 - 3.8e-06 27.4 0.0 0.0002 21.8 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain Viral_helicase1 PF01443.18 ORY01490.1 - 2.7e-05 24.0 0.0 4.2e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 ORY01490.1 - 8.8e-05 22.8 0.1 0.12 12.7 0.0 2.5 1 1 1 2 2 2 2 AAA domain RuvB_N PF05496.12 ORY01490.1 - 0.0001 22.1 0.0 0.00024 20.9 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_3 PF07726.11 ORY01490.1 - 0.00021 21.2 0.0 0.00036 20.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta PF06144.13 ORY01490.1 - 0.0017 18.2 0.0 0.0025 17.6 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.15 ORY01490.1 - 0.0029 17.6 0.0 0.0054 16.7 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain Mg_chelatase PF01078.21 ORY01490.1 - 0.0029 17.0 0.0 0.02 14.3 0.0 2.0 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI MeaB PF03308.16 ORY01490.1 - 0.0052 15.8 0.0 0.0094 15.0 0.0 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_11 PF13086.6 ORY01490.1 - 0.013 15.3 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 ORY01490.1 - 0.02 14.8 0.0 0.077 12.9 0.0 2.0 3 0 0 3 3 2 0 NTPase AAA_19 PF13245.6 ORY01490.1 - 0.023 15.0 0.2 0.1 12.9 0.2 2.0 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 ORY01490.1 - 0.028 14.1 0.1 0.081 12.6 0.1 1.7 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 ORY01490.1 - 0.032 13.6 0.0 3.2 7.1 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein DEAD PF00270.29 ORY01490.1 - 0.037 13.8 0.1 1.1 9.0 0.0 2.3 1 1 1 2 2 2 0 DEAD/DEAH box helicase AAA_assoc_2 PF16193.5 ORY01490.1 - 0.04 14.3 0.0 0.13 12.6 0.0 1.9 1 0 0 1 1 1 0 AAA C-terminal domain KTI12 PF08433.10 ORY01490.1 - 0.058 12.8 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_24 PF13479.6 ORY01490.1 - 0.084 12.6 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 ORY01490.1 - 0.14 11.7 0.0 0.7 9.4 0.1 2.1 2 1 0 2 2 2 0 AAA domain Asp PF00026.23 ORY01491.1 - 1.9e-75 254.2 0.9 2.2e-75 254.0 0.9 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 ORY01491.1 - 9.8e-13 48.7 1.4 6.8e-12 46.0 0.4 2.6 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 ORY01491.1 - 6.3e-05 23.5 0.4 1.7 9.3 0.1 3.9 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.6 ORY01491.1 - 0.001 18.8 0.0 0.026 14.3 0.0 2.7 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal ER_lumen_recept PF00810.18 ORY01492.1 - 8.2e-55 185.7 7.8 1.4e-54 184.9 7.8 1.4 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.14 ORY01492.1 - 0.0031 17.2 11.1 0.73 9.6 0.1 4.3 4 1 1 5 5 5 3 PQ loop repeat Glyco_hydro_85 PF03644.13 ORY01493.1 - 1.9e-78 264.0 0.0 2.8e-78 263.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 DUF445 PF04286.12 ORY01494.1 - 0.0046 16.8 3.5 0.0046 16.8 3.5 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF445) MARVEL PF01284.23 ORY01495.1 - 1.7e-14 54.1 16.9 2.1e-14 53.8 16.9 1.1 1 0 0 1 1 1 1 Membrane-associating domain LVIVD PF08309.11 ORY01495.1 - 0.081 12.3 0.1 0.22 10.8 0.1 1.7 1 0 0 1 1 1 0 LVIVD repeat Rad51 PF08423.11 ORY01497.1 - 0.008 15.5 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 Rad51 Carn_acyltransf PF00755.20 ORY01498.1 - 1.8e-207 690.6 0.0 2.8e-207 690.0 0.0 1.3 1 1 0 1 1 1 1 Choline/Carnitine o-acyltransferase zf-rbx1 PF12678.7 ORY01498.1 - 0.18 12.1 0.1 0.49 10.7 0.1 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain DUF1387 PF07139.11 ORY01499.1 - 0.22 11.2 5.1 0.29 10.8 5.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) DNA_pol_phi PF04931.13 ORY01499.1 - 1.4 6.9 6.2 1.7 6.7 6.2 1.2 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 ORY01499.1 - 7.4 5.8 7.0 18 4.6 7.0 1.6 1 0 0 1 1 1 0 NOA36 protein Astro_capsid_p PF12226.8 ORY01499.1 - 8.6 5.4 10.6 15 4.6 10.6 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein RNase_HII PF01351.18 ORY01500.1 - 2.1e-50 171.4 0.0 4.8e-49 166.9 0.0 2.0 1 1 0 1 1 1 1 Ribonuclease HII AWPM-19 PF05512.11 ORY01500.1 - 0.019 15.2 0.0 0.032 14.4 0.0 1.3 1 0 0 1 1 1 0 AWPM-19-like family WD40 PF00400.32 ORY01501.1 - 2.2e-22 78.9 5.6 0.016 16.1 0.0 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat PQQ_2 PF13360.6 ORY01501.1 - 0.00016 21.4 1.5 0.054 13.1 0.1 2.7 1 1 1 3 3 3 2 PQQ-like domain ANAPC4_WD40 PF12894.7 ORY01501.1 - 0.00083 19.6 0.2 4 7.8 0.1 3.7 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ORY01501.1 - 0.0019 16.9 0.1 4.5 5.8 0.1 3.8 2 1 1 4 4 4 2 Nucleoporin Nup120/160 Gp5_OB PF06714.11 ORY01502.1 - 0.074 13.3 0.0 0.095 12.9 0.0 1.1 1 0 0 1 1 1 0 Gp5 N-terminal OB domain DUF3585 PF12130.8 ORY01504.1 - 0.0013 18.9 2.0 0.0026 17.9 2.0 1.5 1 0 0 1 1 1 1 Bivalent Mical/EHBP Rab binding domain XRCC4 PF06632.12 ORY01504.1 - 0.0014 17.6 16.8 0.0065 15.4 16.3 1.9 1 1 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 YycI PF09648.10 ORY01504.1 - 0.0062 16.2 2.3 0.64 9.6 0.0 2.1 1 1 1 2 2 2 1 YycH protein DUF4473 PF14747.6 ORY01504.1 - 0.039 14.5 0.3 0.1 13.2 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4473) NPV_P10 PF05531.12 ORY01504.1 - 0.11 13.0 1.7 0.27 11.7 1.7 1.7 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein tRNA-synt_1g PF09334.11 ORY01504.1 - 0.23 10.2 0.4 0.32 9.7 0.4 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (M) DUF4407 PF14362.6 ORY01504.1 - 0.41 10.0 9.8 0.26 10.6 7.9 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) AAA_13 PF13166.6 ORY01504.1 - 7 5.2 9.6 10 4.6 9.6 1.1 1 0 0 1 1 1 0 AAA domain Aminotran_3 PF00202.21 ORY01507.1 - 2.3e-122 408.6 0.0 2.6e-122 408.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III SET PF00856.28 ORY01508.1 - 1.2e-19 71.4 0.3 1.2e-19 71.4 0.3 3.3 2 2 0 2 2 2 1 SET domain SRI PF08236.11 ORY01508.1 - 1.1e-16 60.8 10.8 1.1e-16 60.8 10.8 2.4 2 0 0 2 2 2 1 SRI (Set2 Rpb1 interacting) domain AWS PF17907.1 ORY01508.1 - 3e-10 40.0 12.0 3e-10 40.0 12.0 2.6 2 0 0 2 2 2 1 AWS domain WW PF00397.26 ORY01508.1 - 3.3e-07 30.3 1.9 9.6e-07 28.8 1.9 1.9 1 0 0 1 1 1 1 WW domain Med26 PF08711.11 ORY01508.1 - 1.4e-05 25.0 0.1 4.2e-05 23.5 0.1 1.9 1 0 0 1 1 1 1 TFIIS helical bundle-like domain BEN PF10523.9 ORY01508.1 - 0.012 15.8 0.3 10 6.5 0.0 2.7 2 0 0 2 2 2 0 BEN domain KorB PF08535.10 ORY01508.1 - 0.028 14.4 0.8 0.085 12.9 0.8 1.8 1 0 0 1 1 1 0 KorB domain PRIMA1 PF16101.5 ORY01508.1 - 0.14 12.2 16.7 0.87 9.6 7.9 3.0 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Trp_dioxygenase PF03301.13 ORY01508.1 - 0.48 9.7 4.5 0.76 9.0 4.5 1.2 1 0 0 1 1 1 0 Tryptophan 2,3-dioxygenase VEFS-Box PF09733.9 ORY01510.1 - 2.6e-12 46.7 0.0 5.7e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 VEFS-Box of polycomb protein zf-C2HE PF16278.5 ORY01510.1 - 0.015 15.7 0.1 0.046 14.2 0.1 1.8 1 0 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_2 PF12756.7 ORY01510.1 - 0.028 14.7 4.3 0.031 14.6 2.6 1.9 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 ORY01510.1 - 0.18 12.7 4.0 0.91 10.5 4.0 2.3 1 0 0 1 1 1 0 C2H2-type zinc finger zf-BED PF02892.15 ORY01510.1 - 2.3 8.3 6.5 0.54 10.3 1.8 2.3 2 0 0 2 2 2 0 BED zinc finger LRR_4 PF12799.7 ORY01511.1 - 0.014 15.8 2.9 1.8 9.1 0.1 3.9 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 ORY01511.1 - 0.03 14.2 0.6 0.073 13.0 0.6 1.6 1 0 0 1 1 1 0 F-box-like WW PF00397.26 ORY01512.1 - 3.5e-07 30.2 0.2 0.0024 17.9 0.1 2.5 2 0 0 2 2 2 2 WW domain DUF4629 PF15442.6 ORY01513.1 - 0.033 14.4 0.1 0.051 13.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4629) Gluconate_2-dh3 PF13618.6 ORY01514.1 - 0.16 12.2 1.8 0.71 10.1 0.7 2.5 2 0 0 2 2 2 0 Gluconate 2-dehydrogenase subunit 3 FAA_hydro_N_2 PF18288.1 ORY01514.1 - 0.89 10.0 4.7 1.1 9.8 0.1 3.7 4 0 0 4 4 4 0 Fumarylacetoacetase N-terminal domain 2 MetOD1 PF18546.1 ORY01514.1 - 1.1 9.2 4.4 0.39 10.7 0.3 2.3 3 0 0 3 3 3 0 Metanogen output domain 1 DUF16 PF01519.16 ORY01514.1 - 3.3 8.2 40.3 0.09 13.3 0.5 7.9 4 3 2 6 6 6 0 Protein of unknown function DUF16 LPP PF04728.13 ORY01514.1 - 8.2 6.9 13.7 8.9 6.8 0.2 6.0 6 0 0 6 6 6 0 Lipoprotein leucine-zipper Not1 PF04054.15 ORY01514.1 - 9.8 5.0 6.3 2.4 7.0 0.4 2.7 2 1 0 2 2 2 0 CCR4-Not complex component, Not1 TIP49 PF06068.13 ORY01515.1 - 1.9e-153 510.8 2.7 2.6e-153 510.4 2.7 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 ORY01515.1 - 7.5e-22 77.2 0.3 4.5e-21 74.7 0.2 2.4 2 0 0 2 2 2 1 TIP49 AAA-lid domain RuvB_N PF05496.12 ORY01515.1 - 1.2e-09 38.1 0.5 1.2e-05 25.1 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA PF00004.29 ORY01515.1 - 3.4e-08 34.0 0.3 0.00014 22.3 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) DnaB_C PF03796.15 ORY01515.1 - 9.4e-06 25.1 0.9 1.9e-05 24.1 0.9 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_16 PF13191.6 ORY01515.1 - 3e-05 24.5 0.6 0.00025 21.5 0.6 2.5 1 1 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.21 ORY01515.1 - 0.00029 20.3 1.2 0.0063 15.9 0.5 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 ORY01515.1 - 0.0024 17.9 0.2 0.47 10.4 0.0 3.0 2 1 1 3 3 3 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 ORY01515.1 - 0.0028 17.9 0.2 0.37 11.1 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.6 ORY01515.1 - 0.0074 16.6 2.3 0.23 11.8 2.3 2.7 1 1 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 ORY01515.1 - 0.014 15.1 0.1 5.4 6.7 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_11 PF13086.6 ORY01515.1 - 0.014 15.2 3.4 0.1 12.4 1.3 2.4 2 1 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 ORY01515.1 - 0.03 13.4 0.0 0.047 12.8 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_25 PF13481.6 ORY01515.1 - 0.064 12.8 0.1 0.14 11.7 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 ORY01515.1 - 0.068 13.3 0.0 0.19 11.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain LicD PF04991.13 ORY01516.1 - 2.6e-21 76.8 14.5 2.5e-17 63.8 2.7 2.8 2 1 1 3 3 3 2 LicD family WLM PF08325.10 ORY01517.1 - 1.5e-52 178.4 0.0 2.2e-52 177.9 0.0 1.2 1 0 0 1 1 1 1 WLM domain SprT-like PF10263.9 ORY01517.1 - 0.004 17.0 0.0 0.0076 16.1 0.0 1.5 1 0 0 1 1 1 1 SprT-like family DUF45 PF01863.17 ORY01517.1 - 0.015 15.3 0.0 0.027 14.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF45 ubiquitin PF00240.23 ORY01517.1 - 0.052 13.3 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin family DUF3245 PF11595.8 ORY01518.1 - 0.042 14.3 1.9 0.3 11.6 2.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) HET PF06985.11 ORY01567.1 - 1.6e-28 99.9 0.4 4.3e-28 98.5 0.4 1.8 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Cutinase PF01083.22 ORY01568.1 - 1.3e-37 129.5 0.0 1.5e-37 129.3 0.0 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 ORY01568.1 - 1.5e-05 24.6 0.0 3.4e-05 23.5 0.0 1.6 2 0 0 2 2 2 1 PE-PPE domain VirJ PF06057.11 ORY01568.1 - 0.014 15.2 0.0 0.02 14.8 0.0 1.3 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Cu2_monooxygen PF01082.20 ORY01568.1 - 0.041 14.1 0.0 0.073 13.3 0.0 1.4 1 0 0 1 1 1 0 Copper type II ascorbate-dependent monooxygenase, N-terminal domain DUF1996 PF09362.10 ORY01569.1 - 1.8e-83 280.1 1.8 2.2e-83 279.8 1.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Ribosomal_L40e PF01020.17 ORY01569.1 - 0.0036 17.2 1.1 0.0064 16.4 0.1 1.9 2 0 0 2 2 2 1 Ribosomal L40e family HsbA PF12296.8 ORY01571.1 - 3.2e-21 76.0 4.7 4e-21 75.7 4.7 1.1 1 0 0 1 1 1 1 Hydrophobic surface binding protein A Mce4_CUP1 PF11887.8 ORY01571.1 - 0.00013 21.5 2.2 0.021 14.3 0.5 2.0 1 1 1 2 2 2 2 Cholesterol uptake porter CUP1 of Mce4, putative UBN_AB PF14075.6 ORY01571.1 - 0.1 12.3 0.1 0.15 11.8 0.1 1.3 1 0 0 1 1 1 0 Ubinuclein conserved middle domain Ank_2 PF12796.7 ORY01573.1 - 1.5e-13 51.2 0.7 2.7e-06 27.9 0.3 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ORY01573.1 - 1.6e-12 46.4 0.8 2.1e-06 27.6 0.4 2.8 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 ORY01573.1 - 5.1e-12 45.7 0.8 8.6e-06 26.0 1.0 2.4 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 ORY01573.1 - 4.6e-11 43.0 4.3 0.0012 19.3 0.3 2.7 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 ORY01573.1 - 4.1e-08 33.3 0.2 0.01 16.1 0.2 2.2 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Glyco_hydro_18 PF00704.28 ORY01574.1 - 7.8e-40 137.5 2.2 1.6e-39 136.5 0.1 2.3 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 LysM PF01476.20 ORY01575.1 - 4.6e-29 100.2 3.8 6.7e-06 26.1 0.1 5.4 5 0 0 5 5 5 5 LysM domain HTH_28 PF13518.6 ORY01575.1 - 0.00024 21.2 0.0 4 7.6 0.0 3.9 4 0 0 4 4 4 2 Helix-turn-helix domain DUF2960 PF11173.8 ORY01575.1 - 0.00049 20.5 0.0 21 5.6 0.0 4.7 5 0 0 5 5 5 1 Protein of unknown function (DUF2960) HTH_23 PF13384.6 ORY01575.1 - 0.0024 17.6 0.0 11 6.0 0.0 4.3 5 0 0 5 5 5 1 Homeodomain-like domain UPF0203 PF05254.12 ORY01575.1 - 0.0029 17.8 5.7 27 5.1 0.1 4.5 4 0 0 4 4 4 0 Uncharacterised protein family (UPF0203) DUF4383 PF14325.6 ORY01575.1 - 0.038 14.3 0.1 4.4 7.6 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4383) HTH_29 PF13551.6 ORY01575.1 - 0.061 13.3 0.0 86 3.3 0.0 4.2 5 0 0 5 5 5 0 Winged helix-turn helix LysM PF01476.20 ORY01576.1 - 0.022 14.8 0.0 0.04 14.0 0.0 1.4 1 0 0 1 1 1 0 LysM domain Abhydrolase_1 PF00561.20 ORY01578.1 - 5.5e-15 55.7 0.0 9.3e-15 55.0 0.0 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ORY01578.1 - 2.9e-10 39.8 0.0 5.1e-10 39.0 0.0 1.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ORY01578.1 - 5.4e-07 30.4 0.0 8.1e-07 29.9 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 ORY01578.1 - 0.0012 18.5 0.0 0.0027 17.3 0.0 1.5 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 ORY01578.1 - 0.087 12.3 0.0 4.2 6.8 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family GMC_oxred_N PF00732.19 ORY01579.1 - 4.4e-70 236.4 0.0 5.6e-70 236.0 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 ORY01579.1 - 1.7e-26 93.4 0.0 3.5e-26 92.4 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 ORY01579.1 - 4.3e-05 22.8 0.1 0.031 13.4 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.17 ORY01579.1 - 0.00034 19.9 0.1 0.00068 18.9 0.1 1.4 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 ORY01579.1 - 0.00038 20.1 0.2 0.0073 15.9 0.0 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ORY01579.1 - 0.0028 17.8 0.1 0.0072 16.5 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 ORY01579.1 - 0.0045 16.1 0.0 0.0068 15.5 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein EthD PF07110.11 ORY01580.1 - 6.2e-23 81.8 0.3 7.8e-23 81.4 0.3 1.1 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 ORY01580.1 - 4.4e-07 30.4 0.0 5.6e-07 30.0 0.0 1.3 1 1 0 1 1 1 1 Methylmuconolactone methyl-isomerase Peptidase_M4_C PF02868.15 ORY01581.1 - 1.2e-46 158.6 0.0 2e-46 157.9 0.0 1.3 1 0 0 1 1 1 1 Thermolysin metallopeptidase, alpha-helical domain Peptidase_M4 PF01447.18 ORY01581.1 - 3.2e-28 99.1 0.2 5.3e-28 98.3 0.2 1.3 1 0 0 1 1 1 1 Thermolysin metallopeptidase, catalytic domain Tannase PF07519.11 ORY01583.1 - 1.8e-117 393.2 0.1 2.3e-117 392.8 0.1 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Hydrolase_4 PF12146.8 ORY01583.1 - 0.0046 16.3 0.0 0.099 11.9 0.0 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Response_reg PF00072.24 ORY01584.1 - 7.7e-25 87.2 0.4 2.8e-24 85.4 0.0 2.1 2 0 0 2 2 2 1 Response regulator receiver domain HATPase_c PF02518.26 ORY01584.1 - 3.3e-22 79.1 0.0 7.3e-22 78.0 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 ORY01584.1 - 8.7e-09 35.3 0.0 2.3e-08 33.9 0.0 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_4 PF08448.10 ORY01584.1 - 7.8e-08 32.5 0.0 0.0004 20.6 0.0 2.8 2 0 0 2 2 2 2 PAS fold DUF1828 PF08861.10 ORY01584.1 - 0.0014 18.8 0.0 0.0036 17.5 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function DUF1828 LpxC PF03331.13 ORY01584.1 - 0.0015 18.1 0.0 0.0029 17.2 0.0 1.4 1 0 0 1 1 1 1 UDP-3-O-acyl N-acetylglycosamine deacetylase HATPase_c_3 PF13589.6 ORY01584.1 - 0.016 15.0 0.1 0.037 13.8 0.1 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Oxidored_nitro PF00148.19 ORY01584.1 - 0.095 11.4 0.0 1.1 7.9 0.0 2.3 2 0 0 2 2 2 0 Nitrogenase component 1 type Oxidoreductase TALPID3 PF15324.6 ORY01584.1 - 8.6 3.9 6.4 13 3.3 6.4 1.2 1 0 0 1 1 1 0 Hedgehog signalling target TP1 PF02079.16 ORY01585.1 - 0.34 10.9 30.3 39 4.2 0.1 10.4 1 1 9 10 10 10 0 Nuclear transition protein 1 Pkinase PF00069.25 ORY01586.1 - 7.2e-31 107.5 0.0 7.9e-31 107.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY01586.1 - 1.1e-18 67.5 0.0 1.2e-18 67.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 ORY01586.1 - 6.1e-06 26.3 0.2 6.3e-06 26.3 0.2 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 ORY01586.1 - 5.7e-05 22.6 0.0 8.3e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 ORY01586.1 - 0.00018 20.9 0.0 0.00025 20.5 0.0 1.2 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 ORY01586.1 - 0.0072 15.3 0.0 0.0095 14.9 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 ORY01586.1 - 0.011 15.4 0.0 0.013 15.1 0.0 1.1 1 0 0 1 1 1 0 RIO1 family Pkinase_fungal PF17667.1 ORY01586.1 - 0.027 13.3 0.0 0.033 13.0 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Seadorna_VP7 PF07387.11 ORY01586.1 - 0.043 12.9 0.0 0.055 12.5 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Choline_kinase PF01633.20 ORY01586.1 - 0.051 13.2 0.0 0.069 12.7 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase PIP49_C PF12260.8 ORY01586.1 - 0.051 13.2 0.0 0.066 12.9 0.0 1.1 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 EIIA-man PF03610.16 ORY01586.1 - 0.056 13.7 0.0 0.083 13.1 0.0 1.2 1 0 0 1 1 1 0 PTS system fructose IIA component PAS_9 PF13426.7 ORY01587.1 - 6.1e-14 52.1 0.0 8e-14 51.8 0.0 1.1 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 ORY01587.1 - 0.018 15.0 0.0 0.035 14.1 0.0 1.5 1 1 0 1 1 1 0 PAS fold PAS_8 PF13188.7 ORY01587.1 - 0.022 14.8 0.0 0.037 14.1 0.0 1.3 1 0 0 1 1 1 0 PAS domain PAS_3 PF08447.12 ORY01587.1 - 0.023 14.9 0.0 0.058 13.7 0.0 1.6 2 0 0 2 2 2 0 PAS fold PAS_4 PF08448.10 ORY01587.1 - 0.13 12.5 0.0 0.27 11.5 0.0 1.5 1 1 0 1 1 1 0 PAS fold HET PF06985.11 ORY01590.1 - 0.00071 19.9 0.3 0.00087 19.7 0.3 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) TPR_12 PF13424.6 ORY01656.1 - 1.4e-28 99.0 13.6 3.3e-08 33.7 0.1 7.5 3 1 5 8 8 8 7 Tetratricopeptide repeat TPR_10 PF13374.6 ORY01656.1 - 1.9e-19 68.9 10.6 0.062 13.2 0.0 8.9 8 1 0 8 8 8 5 Tetratricopeptide repeat Helo_like_N PF17111.5 ORY01656.1 - 3.7e-05 23.2 0.6 0.00011 21.7 0.6 1.8 1 1 0 1 1 1 1 Fungal N-terminal domain of STAND proteins NB-ARC PF00931.22 ORY01656.1 - 0.00013 21.2 0.0 0.00042 19.6 0.0 1.9 2 0 0 2 2 2 1 NB-ARC domain TPR_MalT PF17874.1 ORY01656.1 - 0.00036 20.0 2.4 0.013 14.9 0.8 3.0 1 1 2 3 3 3 1 MalT-like TPR region NACHT PF05729.12 ORY01656.1 - 0.0079 16.1 0.0 0.025 14.5 0.0 1.8 2 0 0 2 2 2 1 NACHT domain TPR_16 PF13432.6 ORY01656.1 - 0.0084 16.7 0.4 6.3 7.5 0.0 4.5 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 ORY01656.1 - 0.0086 16.8 1.8 71 4.6 0.0 5.4 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 ORY01656.1 - 0.011 16.3 0.6 0.78 10.3 0.0 3.8 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 ORY01656.1 - 0.023 14.5 4.3 0.62 10.0 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 ORY01656.1 - 0.038 14.1 6.1 0.48 10.7 0.1 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 ORY01656.1 - 0.048 13.9 2.0 31 5.1 0.1 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Cation_efflux PF01545.21 ORY01657.1 - 1e-16 61.3 9.4 1.3e-16 60.9 9.4 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 ORY01657.1 - 1.4e-11 44.4 2.6 1.6e-11 44.2 0.8 2.0 2 0 0 2 2 2 1 Dimerisation domain of Zinc Transporter DHHC PF01529.20 ORY01657.1 - 1.3 9.1 4.3 0.31 11.1 0.3 2.0 3 0 0 3 3 3 0 DHHC palmitoyltransferase APH PF01636.23 ORY01658.1 - 1.1e-08 35.3 0.0 2e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 ORY01658.1 - 0.033 13.8 0.0 0.048 13.2 0.0 1.1 1 0 0 1 1 1 0 Choline/ethanolamine kinase AA_permease_2 PF13520.6 ORY01659.1 - 5.8e-46 157.2 60.0 7.3e-46 156.9 60.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ORY01659.1 - 1.4e-27 96.4 51.6 1.8e-27 96.1 51.6 1.0 1 0 0 1 1 1 1 Amino acid permease GAPT PF11770.8 ORY01659.1 - 0.079 12.8 0.1 0.079 12.8 0.1 1.9 2 0 0 2 2 2 0 GRB2-binding adapter (GAPT) 2-Hacid_dh_C PF02826.19 ORY01660.1 - 1.8e-37 128.4 0.0 4.3e-37 127.2 0.0 1.6 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 ORY01660.1 - 1.6e-24 86.1 0.0 2e-24 85.8 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain IlvN PF07991.12 ORY01660.1 - 0.02 14.4 0.0 0.29 10.7 0.0 2.2 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain F420_oxidored PF03807.17 ORY01660.1 - 0.03 14.9 0.0 0.11 13.1 0.0 1.9 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent AdoHcyase_NAD PF00670.21 ORY01660.1 - 0.084 12.9 0.0 0.48 10.5 0.0 2.0 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain XdhC_C PF13478.6 ORY01660.1 - 0.09 13.3 0.0 3.3 8.2 0.0 2.3 2 0 0 2 2 2 0 XdhC Rossmann domain PHD PF00628.29 ORY01661.1 - 2.4e-05 24.1 7.5 3.9e-05 23.4 7.5 1.3 1 0 0 1 1 1 1 PHD-finger SDA1 PF05285.12 ORY01662.1 - 3.3e-96 322.8 31.2 3.3e-96 322.8 31.2 2.2 2 0 0 2 2 2 2 SDA1 NUC130_3NT PF08158.12 ORY01662.1 - 3.3e-23 81.8 0.1 7.6e-23 80.6 0.1 1.7 1 0 0 1 1 1 1 NUC130/3NT domain p450 PF00067.22 ORY01663.1 - 4.8e-22 78.3 0.0 5.5e-21 74.8 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 Glyco_hydro_11 PF00457.17 ORY01665.1 - 1.8e-62 210.1 16.6 2.1e-62 209.9 16.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 DUF4870 PF09685.10 ORY01666.1 - 0.0068 16.5 3.6 2.3 8.4 0.0 3.5 3 0 0 3 3 3 2 Domain of unknown function (DUF4870) HET PF06985.11 ORY01668.1 - 2.5e-30 105.7 0.1 3e-30 105.5 0.1 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Pentaxin PF00354.17 ORY01668.1 - 0.053 13.2 0.0 0.23 11.2 0.0 1.9 2 0 0 2 2 2 0 Pentaxin family 7TMR-DISM_7TM PF07695.11 ORY01669.1 - 0.011 15.7 11.5 0.63 9.9 5.5 2.3 2 0 0 2 2 2 0 7TM diverse intracellular signalling FAD_binding_4 PF01565.23 ORY01670.1 - 1.8e-20 73.1 1.1 3.8e-20 72.0 1.1 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 ORY01670.1 - 1.4e-14 53.9 0.0 4.3e-14 52.3 0.0 1.9 1 0 0 1 1 1 1 Berberine and berberine like PhyH PF05721.13 ORY01672.1 - 2.8e-09 37.5 0.2 1e-08 35.7 0.0 2.0 2 1 0 2 2 2 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 ORY01672.1 - 8e-05 21.6 0.1 0.56 8.9 0.0 3.0 3 0 0 3 3 3 3 Protein of unknown function (DUF1479) 2OG-FeII_Oxy_5 PF13759.6 ORY01672.1 - 0.07 13.5 0.0 0.14 12.6 0.0 1.4 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase PNP_UDP_1 PF01048.20 ORY01672.1 - 0.16 11.2 0.0 0.25 10.5 0.0 1.3 1 0 0 1 1 1 0 Phosphorylase superfamily FAD_binding_3 PF01494.19 ORY01673.1 - 1e-19 71.0 0.0 1.9e-19 70.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.14 ORY01673.1 - 6.8e-09 35.1 0.9 0.00077 18.4 0.5 2.9 2 1 0 3 3 3 2 Tryptophan halogenase Pyr_redox_2 PF07992.14 ORY01673.1 - 5.4e-08 32.4 0.7 0.0001 21.6 0.2 2.3 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ORY01673.1 - 2.3e-07 30.7 2.7 3.7e-05 23.5 1.5 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ORY01673.1 - 1.5e-06 28.3 0.1 3.6e-06 27.1 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 ORY01673.1 - 0.00012 21.4 0.8 0.00022 20.5 0.8 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 ORY01673.1 - 0.00048 19.5 0.2 0.0012 18.2 0.1 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ORY01673.1 - 0.0015 17.3 0.5 0.0028 16.4 0.2 1.6 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_9 PF13454.6 ORY01673.1 - 0.0055 16.7 0.9 0.13 12.2 0.9 2.5 1 1 0 1 1 1 1 FAD-NAD(P)-binding GIDA PF01134.22 ORY01673.1 - 0.0074 15.4 1.6 0.021 14.0 1.6 1.7 1 1 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.27 ORY01673.1 - 0.024 15.2 0.3 0.055 14.0 0.3 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 ORY01673.1 - 0.025 13.9 0.4 1.4 8.1 0.1 2.3 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.21 ORY01673.1 - 0.035 13.4 0.3 0.093 12.0 0.2 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 ORY01673.1 - 0.035 13.2 2.3 0.37 9.8 2.4 2.2 2 1 0 2 2 2 0 Lycopene cyclase protein Thi4 PF01946.17 ORY01673.1 - 0.053 12.8 0.1 0.092 12.0 0.1 1.4 1 0 0 1 1 1 0 Thi4 family FAD_oxidored PF12831.7 ORY01673.1 - 0.056 12.8 0.2 0.089 12.1 0.2 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase SE PF08491.10 ORY01673.1 - 0.099 11.7 0.0 10 5.0 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase MCRA PF06100.11 ORY01673.1 - 0.11 11.3 0.1 0.16 10.7 0.1 1.2 1 0 0 1 1 1 0 MCRA family zf-H2C2_2 PF13465.6 ORY01674.1 - 3.1e-07 30.5 1.1 2.7e-05 24.4 0.6 2.4 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2 PF00096.26 ORY01674.1 - 7.9e-06 26.1 9.1 0.00066 20.0 2.9 3.0 2 1 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY01674.1 - 6.3e-05 23.5 5.1 0.013 16.3 2.4 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 ORY01674.1 - 0.0061 16.5 2.0 0.0061 16.5 2.0 1.9 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_11 PF16622.5 ORY01674.1 - 0.019 14.7 1.9 0.61 9.9 0.4 2.7 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_3 PF13878.6 ORY01674.1 - 0.022 14.6 1.6 0.48 10.3 0.0 2.2 1 1 1 2 2 2 0 zinc-finger of acetyl-transferase ESCO zf-met PF12874.7 ORY01674.1 - 0.064 13.7 1.4 0.064 13.7 1.4 2.3 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zinc_ribbon_15 PF17032.5 ORY01674.1 - 0.072 13.9 0.5 0.11 13.3 0.5 1.2 1 0 0 1 1 1 0 zinc-ribbon family Spore_III_AB PF09548.10 ORY01674.1 - 0.12 12.5 0.0 0.17 12.0 0.0 1.1 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) zf-C2HE PF16278.5 ORY01674.1 - 0.21 12.1 1.9 1.1 9.8 0.2 2.2 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger Cytochrome_C7 PF14522.6 ORY01674.1 - 0.22 11.5 3.9 0.56 10.2 3.7 1.6 1 1 1 2 2 2 0 Cytochrome c7 and related cytochrome c zf-C2H2_jaz PF12171.8 ORY01674.1 - 1.5 9.2 5.6 0.79 10.1 0.7 2.4 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Fungal_trans PF04082.18 ORY01675.1 - 7e-05 22.0 0.3 0.00015 20.9 0.3 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain PreAtp-grasp PF18604.1 ORY01675.1 - 0.15 11.7 0.1 0.79 9.4 0.1 2.0 2 0 0 2 2 2 0 Pre ATP-grasp domain MFS_1 PF07690.16 ORY01676.1 - 1.5e-14 53.7 24.6 1.5e-14 53.7 24.6 2.9 1 1 2 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY01676.1 - 4e-06 26.0 10.7 4e-06 26.0 10.7 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter Peptidase_S15 PF02129.18 ORY01678.1 - 2.2e-37 129.1 0.0 6.5e-36 124.3 0.0 2.1 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 ORY01678.1 - 5.7e-33 114.7 0.0 1.2e-32 113.7 0.0 1.5 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain PhyH PF05721.13 ORY01679.1 - 1.3e-05 25.6 0.1 8.7e-05 22.9 0.1 2.0 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 ORY01679.1 - 0.00031 19.6 0.0 0.17 10.6 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1479) CFEM PF05730.11 ORY01680.1 - 2e-11 43.8 13.6 3.5e-11 43.0 13.6 1.4 1 0 0 1 1 1 1 CFEM domain Tenui_NS3 PF05310.12 ORY01680.1 - 0.028 14.5 0.0 0.052 13.7 0.0 1.3 1 0 0 1 1 1 0 Tenuivirus movement protein LIN52 PF10044.9 ORY01681.1 - 0.17 12.6 1.1 4.1 8.2 0.3 2.8 3 0 0 3 3 3 0 Retinal tissue protein Sugar_tr PF00083.24 ORY01682.1 - 9.6e-78 262.0 23.6 2.5e-66 224.4 10.1 1.9 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 ORY01682.1 - 3e-29 102.0 22.7 4e-28 98.4 19.0 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_5 PF05631.14 ORY01682.1 - 1.6e-05 24.0 5.9 3.9e-05 22.8 0.9 2.2 2 0 0 2 2 2 2 Sugar-tranasporters, 12 TM MFS_2 PF13347.6 ORY01682.1 - 2.6e-05 23.0 22.9 8.1e-05 21.4 2.2 3.0 3 0 0 3 3 3 2 MFS/sugar transport protein TRI12 PF06609.13 ORY01682.1 - 9.1e-05 21.1 0.3 9.1e-05 21.1 0.3 2.7 3 0 0 3 3 3 2 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.7 ORY01682.1 - 0.6 8.9 25.3 0.29 9.9 8.6 3.2 3 0 0 3 3 3 0 MFS_1 like family Glyco_hydro_61 PF03443.14 ORY01684.1 - 8.6e-31 107.5 0.0 1.1e-30 107.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Alpha_E3_glycop PF01563.16 ORY01684.1 - 0.089 12.9 0.0 0.24 11.5 0.0 1.7 1 0 0 1 1 1 0 Alphavirus E3 glycoprotein Citrate_synt PF00285.21 ORY01722.1 - 0.024 13.7 0.0 0.032 13.3 0.0 1.1 1 0 0 1 1 1 0 Citrate synthase, C-terminal domain Pec_lyase_C PF00544.19 ORY01723.1 - 4.7e-37 127.6 8.8 5.9e-37 127.3 8.8 1.2 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 ORY01723.1 - 5.6e-05 23.1 12.5 0.00069 19.5 12.5 2.2 1 1 0 1 1 1 1 Right handed beta helix region MFS_1 PF07690.16 ORY01724.1 - 3.2e-37 128.3 49.1 3.6e-37 128.1 45.3 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 ORY01724.1 - 1.3e-19 70.1 12.0 1.3e-19 70.1 12.0 1.4 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 ORY01724.1 - 2.7e-11 43.0 13.2 2.7e-11 43.0 13.2 3.0 3 0 0 3 3 3 1 Sugar (and other) transporter OATP PF03137.20 ORY01724.1 - 0.0036 15.7 1.7 0.0036 15.7 1.7 2.1 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family p450 PF00067.22 ORY01725.1 - 1.2e-31 110.0 0.0 1.7e-29 102.9 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 Glyco_tran_28_C PF04101.16 ORY01728.1 - 3e-08 33.8 0.1 4.3e-08 33.3 0.1 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain UDPGT PF00201.18 ORY01728.1 - 2.6e-06 26.5 0.2 8.1e-06 24.9 0.2 1.8 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_trans_1_4 PF13692.6 ORY01728.1 - 0.049 14.1 0.1 0.093 13.2 0.1 1.5 1 0 0 1 1 1 0 Glycosyl transferases group 1 MFS_1 PF07690.16 ORY01729.1 - 4.5e-42 144.2 49.8 4.5e-42 144.2 49.8 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY01729.1 - 1.3e-07 30.8 32.5 2.4e-05 23.4 12.4 2.7 2 1 0 2 2 2 2 Sugar (and other) transporter GFA PF04828.14 ORY01731.1 - 3.7e-21 75.2 2.7 9.7e-13 48.3 0.2 3.5 2 1 1 3 3 3 2 Glutathione-dependent formaldehyde-activating enzyme Cys_rich_CWC PF14375.6 ORY01731.1 - 6.3 7.3 9.9 0.66 10.4 3.3 2.5 2 1 0 2 2 2 0 Cysteine-rich CWC CorA PF01544.18 ORY01732.1 - 0.0039 16.5 1.7 0.0048 16.3 1.7 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein BatD PF13584.6 ORY01732.1 - 0.12 11.2 0.6 0.12 11.1 0.6 1.1 1 0 0 1 1 1 0 Oxygen tolerance AKAP95 PF04988.12 ORY01733.1 - 0.083 13.1 0.0 0.21 11.8 0.0 1.7 2 0 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) DUF1077 PF06417.12 ORY01735.1 - 2e-45 153.6 2.9 2.5e-45 153.3 2.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) Adaptin_N PF01602.20 ORY01736.1 - 1.3e-122 410.0 7.1 1.7e-122 409.7 7.1 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 ORY01736.1 - 1.2e-56 191.2 6.0 3.6e-56 189.7 0.2 3.2 3 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 ORY01736.1 - 3.4e-13 48.6 0.5 0.00026 21.0 0.0 5.4 5 0 0 5 5 5 3 HEAT repeat HEAT_2 PF13646.6 ORY01736.1 - 9.4e-13 48.4 4.0 1.6e-07 31.6 0.2 4.2 4 0 0 4 4 4 3 HEAT repeats HEAT_EZ PF13513.6 ORY01736.1 - 0.00032 21.1 0.2 0.42 11.2 0.0 4.9 4 1 1 5 5 5 1 HEAT-like repeat Arm PF00514.23 ORY01736.1 - 0.00082 19.3 0.9 3.2 7.9 0.0 4.2 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat CLASP_N PF12348.8 ORY01736.1 - 0.0027 17.3 1.5 0.44 10.1 0.0 3.5 4 0 0 4 4 4 1 CLASP N terminal RTP1_C1 PF10363.9 ORY01736.1 - 0.0075 16.4 1.6 1.3 9.2 0.1 3.3 2 1 1 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 DUF2496 PF10689.9 ORY01736.1 - 0.021 14.6 0.2 0.11 12.3 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2496) T_hemolysin PF12261.8 ORY01736.1 - 0.15 11.8 0.0 0.55 10.0 0.0 1.8 2 0 0 2 2 2 0 Thermostable hemolysin MMR_HSR1 PF01926.23 ORY01737.1 - 0.0031 17.6 0.0 0.021 14.9 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 ORY01737.1 - 0.016 14.6 0.5 5.4 6.3 0.1 3.3 3 0 0 3 3 3 0 FtsK/SpoIIIE family Sugar_tr PF00083.24 ORY01739.1 - 1.2e-74 251.9 23.5 1.4e-74 251.6 23.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY01739.1 - 7.1e-21 74.5 23.6 9.7e-21 74.1 23.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Lipase_GDSL_2 PF13472.6 ORY01740.1 - 1.4e-07 32.1 1.3 6.9e-06 26.6 0.2 2.6 2 1 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 ORY01740.1 - 0.00042 20.3 0.3 0.0023 17.9 0.3 2.2 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Elf4 PF07011.11 ORY01740.1 - 0.025 14.5 0.6 0.049 13.6 0.6 1.4 1 0 0 1 1 1 0 Early Flowering 4 domain DUF1774 PF08611.10 ORY01743.1 - 1.5e-37 127.8 2.2 1.5e-37 127.8 2.2 3.0 3 1 1 4 4 4 1 Fungal protein of unknown function (DUF1774) Hist_deacetyl PF00850.19 ORY01744.1 - 1.4e-48 165.9 0.0 2.4e-48 165.2 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain RTP801_C PF07809.11 ORY01744.1 - 0.12 12.3 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 RTP801 C-terminal region F-box-like PF12937.7 ORY01745.1 - 5.3e-06 26.2 0.4 5.3e-06 26.2 0.4 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 ORY01745.1 - 0.00021 21.1 0.3 0.00021 21.1 0.3 1.8 2 0 0 2 2 2 1 F-box domain F-box_4 PF15966.5 ORY01745.1 - 0.081 12.8 0.4 0.21 11.5 0.1 1.8 2 0 0 2 2 2 0 F-box Peptidase_M28 PF04389.17 ORY01747.1 - 8.8e-37 126.7 0.0 1.3e-36 126.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 ORY01747.1 - 2e-10 40.5 0.1 4.7e-10 39.4 0.1 1.7 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 ORY01747.1 - 0.0027 17.5 0.0 0.0045 16.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 UCH PF00443.29 ORY01748.1 - 0.023 14.2 0.1 0.04 13.4 0.1 1.2 1 1 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase adh_short PF00106.25 ORY01749.1 - 4.3e-32 111.2 0.0 7.4e-32 110.4 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY01749.1 - 3.4e-26 92.2 0.0 4.9e-26 91.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY01749.1 - 2.2e-07 31.0 0.0 3.2e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 ORY01749.1 - 6.7e-06 25.7 0.0 8.7e-06 25.3 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) MFS_1 PF07690.16 ORY01750.1 - 6.7e-36 123.9 24.8 1e-35 123.3 24.8 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 ORY01750.1 - 2.1e-07 30.6 2.7 2.1e-07 30.6 2.7 2.3 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB DUF3593 PF12159.8 ORY01750.1 - 0.039 14.0 0.5 0.19 11.8 0.5 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3593) Saf_2TM PF18303.1 ORY01750.1 - 0.19 11.3 3.8 0.61 9.7 0.0 3.0 3 1 0 3 3 3 0 SAVED-fused 2TM effector domain IspA PF04279.15 ORY01750.1 - 5.8 7.1 12.3 0.14 12.4 0.4 3.3 2 2 0 3 3 3 0 Intracellular septation protein A Transp_cyt_pur PF02133.15 ORY01751.1 - 4.4e-74 249.8 33.7 2.3e-73 247.4 33.7 1.8 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin PrgI PF12666.7 ORY01751.1 - 9.5 7.0 20.4 0.18 12.5 0.9 3.9 3 1 0 3 3 3 0 PrgI family protein Fungal_trans PF04082.18 ORY01752.1 - 1.6e-28 99.5 0.3 2.5e-28 98.9 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY01752.1 - 9.9e-08 32.0 8.7 9.9e-08 32.0 8.7 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Amidase PF01425.21 ORY01753.1 - 2.3e-14 53.2 0.0 1.4e-12 47.4 0.0 2.4 1 1 0 1 1 1 1 Amidase HET PF06985.11 ORY01801.1 - 1.9e-27 96.4 0.1 4e-27 95.4 0.1 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) AAA PF00004.29 ORY01802.1 - 6.5e-21 75.1 0.0 1.3e-20 74.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 ORY01802.1 - 0.00034 20.6 1.6 0.0014 18.6 0.2 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 ORY01802.1 - 0.00062 20.1 1.6 0.028 14.7 1.6 2.9 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 ORY01802.1 - 0.0023 17.7 0.0 0.0052 16.5 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 ORY01802.1 - 0.0024 18.3 0.1 0.0085 16.5 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 ORY01802.1 - 0.005 17.4 0.0 0.033 14.7 0.0 2.4 2 1 0 2 2 2 1 AAA domain ATPase PF06745.13 ORY01802.1 - 0.0087 15.4 0.8 0.21 10.9 0.2 2.4 2 0 0 2 2 2 1 KaiC IstB_IS21 PF01695.17 ORY01802.1 - 0.013 15.3 0.0 0.27 10.9 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_17 PF13207.6 ORY01802.1 - 0.016 15.7 0.0 0.047 14.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain Zot PF05707.12 ORY01802.1 - 0.019 14.6 0.1 0.31 10.6 0.1 2.3 1 1 0 2 2 2 0 Zonular occludens toxin (Zot) AAA_2 PF07724.14 ORY01802.1 - 0.042 14.0 0.0 0.13 12.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 ORY01802.1 - 0.051 12.8 0.3 0.099 11.8 0.0 1.5 2 0 0 2 2 2 0 TIP49 P-loop domain Rad17 PF03215.15 ORY01802.1 - 0.062 13.2 0.8 0.27 11.2 0.0 2.6 4 0 0 4 4 4 0 Rad17 P-loop domain AAA_14 PF13173.6 ORY01802.1 - 0.073 13.1 0.0 0.41 10.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 ORY01802.1 - 0.11 11.9 0.1 0.22 10.9 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Vps36_ESCRT-II PF11605.8 ORY01802.1 - 0.17 12.1 0.1 1.1 9.4 0.0 2.4 3 0 0 3 3 3 0 Vacuolar protein sorting protein 36 Vps36 AAA_19 PF13245.6 ORY01802.1 - 0.35 11.2 2.1 1.7 9.0 2.1 2.0 1 1 0 1 1 1 0 AAA domain Heme_oxygenase PF01126.20 ORY01804.1 - 7.8e-12 45.4 0.0 2.2e-10 40.7 0.0 2.3 2 0 0 2 2 2 2 Heme oxygenase zf-C2H2_4 PF13894.6 ORY01805.1 - 5.2e-08 33.1 32.5 0.22 12.5 0.3 8.0 7 1 0 7 7 7 4 C2H2-type zinc finger zf-C2H2 PF00096.26 ORY01805.1 - 6.7e-08 32.6 33.0 0.04 14.4 0.0 6.9 6 1 0 6 6 6 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY01805.1 - 3.4e-05 24.1 42.1 0.055 13.9 0.2 7.8 8 0 0 8 8 8 3 Zinc-finger double domain zf-C2H2_2 PF12756.7 ORY01805.1 - 0.0012 19.2 19.0 0.014 15.7 0.1 4.1 3 1 1 4 4 4 3 C2H2 type zinc-finger (2 copies) IBR PF01485.21 ORY01805.1 - 0.015 15.5 1.1 0.015 15.5 1.1 4.4 2 1 2 4 4 4 0 IBR domain, a half RING-finger domain Actin_micro PF17003.5 ORY01805.1 - 0.055 12.7 0.0 0.13 11.4 0.0 1.5 1 1 0 1 1 1 0 Putative actin-like family zf-C2HE PF16278.5 ORY01805.1 - 0.76 10.3 13.0 9.5 6.8 0.1 4.1 4 0 0 4 4 4 0 C2HE / C2H2 / C2HC zinc-binding finger DJ-1_PfpI PF01965.24 ORY01806.1 - 1.3e-07 31.5 0.0 5.1e-07 29.6 0.0 1.9 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 ORY01806.1 - 0.14 11.9 0.1 0.31 10.7 0.0 1.6 2 0 0 2 2 2 0 ThiJ/PfpI family-like UQ_con PF00179.26 ORY01807.1 - 2.7e-19 69.2 0.0 4e-19 68.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 ORY01807.1 - 0.084 13.2 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 RWD domain Fringe PF02434.16 ORY01811.1 - 1.7e-05 24.4 0.5 0.0001 21.9 0.5 2.1 1 1 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 ORY01811.1 - 0.007 16.2 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 Galactosyltransferase PAN_3 PF08277.12 ORY01811.1 - 0.016 15.0 0.8 0.037 13.8 0.8 1.6 1 0 0 1 1 1 0 PAN-like domain PAN_4 PF14295.6 ORY01811.1 - 0.022 14.6 4.3 0.061 13.2 4.3 1.8 1 0 0 1 1 1 0 PAN domain Rep_fac-A_3 PF08661.11 ORY01813.1 - 2.5e-24 85.6 0.0 2.8e-24 85.5 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 Spb1_C PF07780.12 ORY01815.1 - 1.4e-85 286.3 18.4 1.4e-85 286.3 18.4 3.4 4 1 0 4 4 4 1 Spb1 C-terminal domain FtsJ PF01728.19 ORY01815.1 - 2.4e-55 187.4 0.0 4.7e-55 186.4 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.8 ORY01815.1 - 3.5e-51 173.3 14.7 3.5e-51 173.3 14.7 4.4 5 1 1 6 6 6 1 Domain of unknown function (DUF3381) ICL PF00463.21 ORY01816.1 - 5.7e-116 388.1 0.7 6.8e-116 387.8 0.7 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 ORY01816.1 - 1e-06 28.4 0.0 1.7e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Choline_sulf_C PF12411.8 ORY01816.1 - 0.17 11.7 1.2 0.32 10.8 0.3 1.9 2 0 0 2 2 2 0 Choline sulfatase enzyme C terminal MFS_1 PF07690.16 ORY01817.1 - 1.2e-32 113.2 25.9 1.8e-32 112.7 25.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily GATase PF00117.28 ORY01818.1 - 0.0037 17.1 0.0 0.005 16.6 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Aminotran_1_2 PF00155.21 ORY01819.1 - 3.1e-14 52.9 0.0 4.6e-14 52.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 ORY01819.1 - 0.0021 16.9 0.2 0.0067 15.3 0.0 1.8 2 0 0 2 2 2 1 Alanine-glyoxylate amino-transferase RNase_Zc3h12a PF11977.8 ORY01819.1 - 0.069 12.9 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Zc3h12a-like Ribonuclease NYN domain Hydantoinase_B PF02538.14 ORY01820.1 - 1.3e-196 654.0 0.3 1.7e-196 653.7 0.3 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 ORY01820.1 - 7e-96 320.9 0.2 1.9e-95 319.5 0.1 1.8 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 ORY01820.1 - 9e-59 198.2 0.1 7.4e-57 191.9 0.0 2.4 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region Proteasome_A_N PF10584.9 ORY01820.1 - 0.023 14.4 0.0 0.049 13.3 0.0 1.6 1 0 0 1 1 1 0 Proteasome subunit A N-terminal signature SOG2 PF10428.9 ORY01822.1 - 9.9 5.2 14.8 11 5.1 14.8 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein 6PF2K PF01591.18 ORY01823.1 - 4.9e-62 209.1 0.0 7e-62 208.6 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 ORY01823.1 - 2e-22 79.9 0.2 1.1e-21 77.5 0.2 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 ORY01823.1 - 0.019 15.2 0.0 0.048 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF1771 PF08590.10 ORY01823.1 - 0.089 13.2 1.2 9.8 6.6 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF1771) Porin_3 PF01459.22 ORY01824.1 - 1.9e-82 276.8 0.0 2.2e-82 276.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic porin Tom22 PF04281.13 ORY01825.1 - 1.7e-48 163.9 1.7 1.9e-48 163.8 1.7 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 Pollen_allerg_1 PF01357.21 ORY01827.1 - 9.7e-11 41.6 0.0 1.9e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 Pollen allergen CBM_1 PF00734.18 ORY01827.1 - 6.2e-10 38.9 7.5 6.2e-10 38.9 7.5 2.5 2 0 0 2 2 2 1 Fungal cellulose binding domain DPBB_1 PF03330.18 ORY01827.1 - 5.1e-05 23.5 0.0 0.00018 21.7 0.0 2.0 1 1 0 1 1 1 1 Lytic transglycolase DUF5348 PF17295.2 ORY01827.1 - 0.057 13.3 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5348) IPPT PF01715.17 ORY01828.1 - 8.2e-63 212.3 0.0 1.1e-62 211.8 0.0 1.1 1 0 0 1 1 1 1 IPP transferase IPT PF01745.16 ORY01828.1 - 7.3e-05 22.3 0.0 0.00013 21.5 0.0 1.4 1 0 0 1 1 1 1 Isopentenyl transferase ABC_tran PF00005.27 ORY01828.1 - 0.0034 17.9 0.0 0.0094 16.5 0.0 1.8 1 0 0 1 1 1 1 ABC transporter zf-met PF12874.7 ORY01828.1 - 0.0039 17.5 0.1 0.009 16.4 0.1 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 ORY01828.1 - 0.0045 17.2 0.0 0.012 15.9 0.0 1.8 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding AAA_33 PF13671.6 ORY01828.1 - 0.01 16.0 0.0 0.47 10.6 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.6 ORY01828.1 - 0.032 14.6 0.0 0.067 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 ORY01828.1 - 0.037 13.6 0.0 0.28 10.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 ORY01828.1 - 0.041 14.4 0.0 1.5 9.4 0.0 2.8 2 0 0 2 2 2 0 AAA domain Rpr2 PF04032.16 ORY01828.1 - 0.066 13.5 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Ploopntkinase3 PF18751.1 ORY01828.1 - 0.066 13.1 0.2 0.63 9.9 0.0 2.4 3 0 0 3 3 3 0 P-loop Nucleotide Kinase3 DUF87 PF01935.17 ORY01828.1 - 0.11 12.5 0.1 0.54 10.3 0.0 2.0 2 0 0 2 2 2 0 Helicase HerA, central domain ABC_tran PF00005.27 ORY01829.1 - 1.2e-15 58.2 0.0 9e-15 55.4 0.0 2.0 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ORY01829.1 - 9.1e-11 42.1 1.6 8.3e-05 22.5 0.2 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ORY01829.1 - 0.0012 18.3 0.0 0.27 10.6 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 ORY01829.1 - 0.0025 17.5 0.2 0.02 14.6 0.1 2.1 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF3584 PF12128.8 ORY01829.1 - 0.0064 14.1 0.0 0.0084 13.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) AAA_28 PF13521.6 ORY01829.1 - 0.012 15.8 0.4 0.059 13.6 0.3 2.0 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 ORY01829.1 - 0.021 15.4 0.0 0.042 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 ORY01829.1 - 0.028 14.2 0.0 0.043 13.6 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 ORY01829.1 - 0.03 14.2 0.0 0.049 13.5 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_25 PF13481.6 ORY01829.1 - 0.034 13.7 0.1 0.063 12.9 0.1 1.4 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 ORY01829.1 - 0.059 13.0 0.0 0.092 12.4 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_15 PF13175.6 ORY01829.1 - 0.068 12.9 0.0 0.093 12.4 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 ORY01829.1 - 0.11 12.9 0.1 0.78 10.2 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 ORY01829.1 - 0.13 12.7 2.1 0.74 10.2 2.1 2.0 1 1 0 1 1 1 0 AAA ATPase domain AAA_13 PF13166.6 ORY01829.1 - 0.13 10.9 0.0 0.18 10.4 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 ORY01829.1 - 0.29 11.4 0.7 0.8 10.0 0.1 2.0 2 0 0 2 2 2 0 AAA domain DUF3176 PF11374.8 ORY01830.1 - 4.9e-10 39.6 0.1 1e-09 38.5 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) DUF2066 PF09839.9 ORY01830.1 - 0.14 11.5 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2066) Anp1 PF03452.14 ORY01832.1 - 2.5e-106 354.9 0.0 2.9e-106 354.7 0.0 1.0 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.26 ORY01832.1 - 0.0016 18.3 0.0 0.0025 17.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 DSX_dimer PF08828.10 ORY01832.1 - 0.12 12.0 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Doublesex dimerisation domain DUF202 PF02656.15 ORY01833.1 - 8.1e-23 80.7 0.5 8.1e-23 80.7 0.5 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Scm3 PF10384.9 ORY01833.1 - 0.087 12.6 0.1 0.14 11.9 0.1 1.3 1 0 0 1 1 1 0 Centromere protein Scm3 DEAD PF00270.29 ORY01834.1 - 1.7e-33 115.8 0.1 4.6e-33 114.4 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY01834.1 - 1.7e-26 92.7 0.0 7.9e-26 90.6 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 ORY01834.1 - 0.0071 16.1 0.0 0.034 13.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain FCH PF00611.23 ORY01835.1 - 1.6e-24 86.0 0.1 1.6e-24 86.0 0.1 2.8 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.6 ORY01835.1 - 1.1e-19 70.0 0.2 9.9e-12 44.5 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain C1_1 PF00130.22 ORY01835.1 - 5.2e-14 51.9 4.2 8.6e-14 51.2 4.2 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_1 PF00018.28 ORY01835.1 - 1e-13 50.6 0.0 1.8e-05 24.2 0.0 2.5 2 0 0 2 2 2 2 SH3 domain SH3_3 PF08239.11 ORY01835.1 - 0.0012 19.1 0.0 0.18 12.1 0.0 2.7 2 0 0 2 2 2 1 Bacterial SH3 domain SH3_10 PF17902.1 ORY01835.1 - 0.014 15.4 0.0 1.7 8.8 0.0 2.7 2 0 0 2 2 2 0 SH3 domain C1_2 PF03107.16 ORY01835.1 - 0.035 14.4 5.4 0.067 13.5 5.4 1.4 1 0 0 1 1 1 0 C1 domain SH3_2 PF07653.17 ORY01835.1 - 0.11 12.2 0.0 1.4 8.7 0.0 2.3 2 0 0 2 2 2 0 Variant SH3 domain TyeA PF09059.10 ORY01835.1 - 0.11 12.6 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 TyeA FapA PF03961.13 ORY01835.1 - 0.2 10.2 6.7 0.1 11.2 1.7 2.5 3 0 0 3 3 3 0 Flagellar Assembly Protein A USP8_interact PF08941.10 ORY01835.1 - 3.2 7.6 5.1 9.3 6.0 0.6 3.1 3 0 0 3 3 3 0 USP8 interacting Aa_trans PF01490.18 ORY01836.1 - 2e-38 132.2 33.3 2.2e-38 132.0 33.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF4538 PF15061.6 ORY01836.1 - 0.037 13.7 1.8 0.037 13.7 1.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4538) Bap31 PF05529.12 ORY01836.1 - 0.1 12.4 1.3 0.39 10.6 1.3 2.0 1 0 0 1 1 1 0 Bap31/Bap29 transmembrane region DUF4305 PF14146.6 ORY01836.1 - 0.11 12.7 5.7 0.27 11.5 0.6 3.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4305) SKG6 PF08693.10 ORY01837.1 - 2.7e-05 23.5 0.1 5.7e-05 22.4 0.1 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Fringe PF02434.16 ORY01838.1 - 0.00011 21.7 0.1 0.00095 18.7 0.1 2.1 1 1 0 1 1 1 1 Fringe-like PAN_4 PF14295.6 ORY01838.1 - 0.038 13.9 1.7 0.077 12.9 1.7 1.5 1 0 0 1 1 1 0 PAN domain COesterase PF00135.28 ORY01839.1 - 2.9e-12 46.3 0.0 3.5e-12 46.0 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Myb_DNA-binding PF00249.31 ORY01889.1 - 4.8e-06 26.7 0.0 1.1e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORY01889.1 - 0.0011 19.1 0.0 0.003 17.8 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Tox-GHH PF15636.6 ORY01889.1 - 0.17 11.9 0.7 0.41 10.6 0.7 1.6 1 0 0 1 1 1 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin zf-RING_2 PF13639.6 ORY01890.1 - 1.4e-09 38.1 10.1 1.4e-09 38.1 10.1 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 ORY01890.1 - 2.2e-08 33.9 10.1 2.2e-08 33.9 10.1 2.5 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 ORY01890.1 - 5.4e-08 32.6 9.1 5.4e-08 32.6 9.1 3.0 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORY01890.1 - 6.6e-08 32.4 9.8 6.6e-08 32.4 9.8 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 ORY01890.1 - 1.6e-07 31.1 6.5 1.6e-07 31.1 6.5 2.6 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORY01890.1 - 1.8e-07 31.1 2.6 1.8e-07 31.1 2.6 3.2 2 1 1 3 3 3 1 RING-type zinc-finger Prok-RING_4 PF14447.6 ORY01890.1 - 3.3e-06 26.8 7.3 3.3e-06 26.8 7.3 2.6 2 1 0 2 2 2 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 ORY01890.1 - 2.3e-05 24.6 9.6 2.3e-05 24.6 9.6 2.7 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 ORY01890.1 - 5.7e-05 23.2 8.7 5.7e-05 23.2 8.7 2.8 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_10 PF16685.5 ORY01890.1 - 0.024 14.8 6.0 0.024 14.8 6.0 2.5 1 1 1 2 2 1 0 zinc RING finger of MSL2 zf-RING_6 PF14835.6 ORY01890.1 - 0.028 14.3 4.1 0.028 14.3 4.1 2.5 2 0 0 2 2 2 0 zf-RING of BARD1-type protein DUF1244 PF06844.11 ORY01890.1 - 0.054 13.7 3.3 0.16 12.2 3.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1244) zf-Nse PF11789.8 ORY01890.1 - 0.12 12.2 2.9 0.27 11.1 2.9 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-P11 PF03854.14 ORY01890.1 - 0.53 10.0 10.6 1.1 9.0 7.1 2.9 2 1 0 2 2 2 0 P-11 zinc finger APH PF01636.23 ORY01891.1 - 2e-12 47.5 0.0 2.5e-10 40.7 0.0 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 ORY01891.1 - 6.6e-09 35.7 0.0 1e-08 35.1 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Ras PF00071.22 ORY01895.1 - 2.3e-18 66.3 0.0 2.9e-18 66.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY01895.1 - 9.7e-08 32.3 0.0 5e-07 30.0 0.0 1.9 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 ORY01895.1 - 0.0082 16.5 0.0 0.019 15.4 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_7 PF12775.7 ORY01895.1 - 0.011 15.2 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Arf PF00025.21 ORY01895.1 - 0.013 14.9 0.1 0.022 14.2 0.1 1.4 1 1 0 1 1 1 0 ADP-ribosylation factor family AAA_22 PF13401.6 ORY01895.1 - 0.023 15.0 0.0 0.036 14.3 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 ORY01895.1 - 0.027 14.5 0.0 0.047 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 ORY01895.1 - 0.042 13.9 0.0 0.057 13.5 0.0 1.6 1 1 0 1 1 1 0 Dynamin family DUF2291 PF10054.9 ORY01895.1 - 0.05 13.3 0.0 0.069 12.9 0.0 1.2 1 0 0 1 1 1 0 Predicted periplasmic lipoprotein (DUF2291) Septin PF00735.18 ORY01895.1 - 0.064 12.5 0.0 0.09 12.0 0.0 1.3 1 0 0 1 1 1 0 Septin RNA_helicase PF00910.22 ORY01895.1 - 0.077 13.4 0.0 0.22 11.9 0.0 1.8 1 1 0 1 1 1 0 RNA helicase Tir_receptor_C PF07489.11 ORY01895.1 - 0.087 12.8 1.5 0.12 12.4 1.1 1.4 1 1 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus MMR_HSR1 PF01926.23 ORY01895.1 - 0.091 12.8 0.1 0.19 11.8 0.1 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_24 PF13479.6 ORY01895.1 - 0.094 12.4 0.0 0.23 11.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain zf-C3H2C3 PF17122.5 ORY01896.1 - 0.19 11.8 3.9 0.29 11.2 3.9 1.5 1 1 0 1 1 1 0 Zinc-finger Synthase_beta PF11421.8 ORY01900.1 - 0.13 13.0 1.0 0.87 10.3 0.0 2.7 3 0 0 3 3 3 0 ATP synthase F1 beta subunit Pkinase PF00069.25 ORY01901.1 - 1.8e-31 109.5 0.0 3e-31 108.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY01901.1 - 1.6e-11 44.0 0.0 2.1e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 ORY01901.1 - 0.0051 16.4 0.0 0.0092 15.6 0.0 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 ORY01901.1 - 0.023 14.6 0.5 0.27 11.1 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family NDT80_PhoG PF05224.12 ORY01907.1 - 9.7e-36 123.7 0.4 1.9e-35 122.8 0.4 1.5 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family FAM60A PF15396.6 ORY01908.1 - 0.025 14.6 0.3 0.037 14.0 0.3 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Zn_clus PF00172.18 ORY01909.1 - 2.4 8.3 8.2 5.7 7.1 8.2 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain HD_3 PF13023.6 ORY01910.1 - 1.1e-37 129.5 0.0 1.5e-37 129.1 0.0 1.2 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 ORY01910.1 - 5.2e-12 45.9 0.0 8.2e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 ORY01910.1 - 0.011 15.9 0.0 0.022 15.0 0.0 1.5 1 0 0 1 1 1 0 HD domain STELLO PF03385.17 ORY01910.1 - 0.11 11.2 0.0 0.15 10.8 0.0 1.1 1 0 0 1 1 1 0 STELLO glycosyltransferases PDE4_UCR PF18100.1 ORY01911.1 - 0.044 14.4 0.0 0.067 13.8 0.0 1.3 1 0 0 1 1 1 0 Phosphodiesterase 4 upstream conserved regions (UCR) DUF5101 PF17031.5 ORY01911.1 - 0.15 12.1 0.0 0.27 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5101) Myb_DNA-binding PF00249.31 ORY01912.1 - 5.7e-12 45.6 0.5 2.9e-10 40.2 0.1 2.3 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORY01912.1 - 4e-06 27.0 0.1 4.3e-05 23.7 0.0 2.2 1 1 1 2 2 2 1 Myb-like DNA-binding domain Aida_C2 PF14186.6 ORY01912.1 - 0.14 11.7 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 Cytoskeletal adhesion LMBR1 PF04791.16 ORY01972.1 - 4e-22 78.8 17.3 1.8e-21 76.7 0.8 2.6 2 1 1 3 3 3 2 LMBR1-like membrane protein Abhydrolase_1 PF00561.20 ORY01973.1 - 2.3e-23 83.2 0.0 3.2e-23 82.7 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORY01973.1 - 1.1e-11 45.7 0.0 1.4e-11 45.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORY01973.1 - 2.5e-11 43.3 0.0 3.1e-10 39.7 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 ORY01973.1 - 0.0024 17.5 0.0 0.0044 16.6 0.0 1.3 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_5 PF12695.7 ORY01973.1 - 0.16 11.8 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF3328 PF11807.8 ORY01974.1 - 4.4e-40 137.8 4.5 5.4e-40 137.5 4.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) WYL PF13280.6 ORY01975.1 - 0.0028 17.7 0.2 0.017 15.2 0.2 2.0 1 1 0 1 1 1 1 WYL domain tRNA_NucTransf2 PF09249.11 ORY01975.1 - 0.0077 16.5 1.5 0.31 11.3 1.2 2.2 1 1 0 1 1 1 1 tRNA nucleotidyltransferase, second domain DUF1198 PF06711.11 ORY01975.1 - 0.14 12.2 0.0 0.31 11.1 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1198) DUF996 PF06195.13 ORY01976.1 - 0.022 15.0 0.2 0.022 15.0 0.2 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF996) CRPA PF05745.11 ORY01976.1 - 2 8.4 5.3 18 5.3 0.1 2.3 2 0 0 2 2 2 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) AA_permease_2 PF13520.6 ORY01977.1 - 7.5e-50 170.0 46.3 9.5e-50 169.6 46.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ORY01977.1 - 4.3e-19 68.5 41.1 6.7e-19 67.8 41.1 1.3 1 1 0 1 1 1 1 Amino acid permease F-box-like_2 PF13013.6 ORY01978.1 - 0.059 13.3 0.5 0.25 11.3 0.0 2.1 3 0 0 3 3 3 0 F-box-like domain IBR PF01485.21 ORY01980.1 - 1.3e-17 63.7 14.1 2.4e-09 37.3 4.0 2.2 2 0 0 2 2 2 2 IBR domain, a half RING-finger domain zf-C2HC5 PF06221.13 ORY01980.1 - 0.094 12.7 0.5 0.094 12.7 0.5 2.7 3 0 0 3 3 3 0 Putative zinc finger motif, C2HC5-type Elf1 PF05129.13 ORY01980.1 - 3.1 7.9 7.0 2.4 8.3 0.3 2.3 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like Stc1 PF12898.7 ORY01981.1 - 0.02 15.5 0.6 0.02 15.5 0.6 2.8 4 0 0 4 4 4 0 Stc1 domain zf-RING_2 PF13639.6 ORY01981.1 - 0.084 13.2 8.4 0.16 12.4 8.4 1.5 1 0 0 1 1 1 0 Ring finger domain SF3b1 PF08920.10 ORY01982.1 - 8.9e-22 77.8 8.3 9.6e-21 74.5 8.3 2.5 1 1 0 1 1 1 1 Splicing factor 3B subunit 1 HEAT PF02985.22 ORY01982.1 - 2.8e-11 42.7 11.7 0.01 16.0 0.1 9.6 12 0 0 12 12 11 3 HEAT repeat HEAT_2 PF13646.6 ORY01982.1 - 4.9e-10 39.7 10.9 0.8 10.1 0.1 8.4 6 1 4 10 10 10 3 HEAT repeats Adaptin_N PF01602.20 ORY01982.1 - 4.5e-08 32.1 0.1 0.021 13.4 0.4 3.6 1 1 2 3 3 3 3 Adaptin N terminal region Cnd1 PF12717.7 ORY01982.1 - 3.5e-07 30.4 6.5 0.81 9.7 0.0 6.4 6 2 1 7 7 7 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 ORY01982.1 - 4.6e-06 27.0 20.4 0.21 12.1 0.0 8.3 9 2 1 10 10 10 3 HEAT-like repeat Vac14_Fab1_bd PF12755.7 ORY01982.1 - 0.00017 22.1 2.8 12 6.6 0.0 6.0 6 1 1 7 7 7 1 Vacuolar 14 Fab1-binding region UNC45-central PF11701.8 ORY01982.1 - 0.0021 18.0 0.0 0.0087 16.0 0.0 2.0 2 0 0 2 2 2 1 Myosin-binding striated muscle assembly central CLASP_N PF12348.8 ORY01982.1 - 0.0097 15.5 0.2 2.1 7.9 0.0 3.8 5 0 0 5 5 5 1 CLASP N terminal DUF4903 PF16246.5 ORY01982.1 - 0.071 12.7 0.1 0.15 11.7 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4903) NUC173 PF08161.12 ORY01982.1 - 0.091 12.4 0.1 5.4 6.6 0.0 3.8 4 1 0 5 5 5 0 NUC173 domain CAS_CSE1 PF03378.15 ORY01982.1 - 0.14 10.7 3.2 1 7.8 0.0 3.3 2 2 2 4 4 4 0 CAS/CSE protein, C-terminus Raco_middle PF17651.1 ORY01982.1 - 0.14 11.8 0.3 15 5.2 0.2 2.8 2 0 0 2 2 2 0 RACo middle region MFS_1 PF07690.16 ORY01985.1 - 6.5e-18 64.8 14.8 9.3e-18 64.3 14.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Peptidase_M56 PF05569.11 ORY01985.1 - 0.017 14.3 0.1 0.017 14.3 0.1 1.9 1 1 0 2 2 2 0 BlaR1 peptidase M56 RAP PF08373.10 ORY01985.1 - 0.2 11.8 1.9 15 5.8 0.3 3.2 3 0 0 3 3 3 0 RAP domain SnoaL PF07366.12 ORY01987.1 - 6.7e-05 22.7 0.0 0.00011 22.0 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase MFS_1 PF07690.16 ORY01990.1 - 1.3e-39 136.1 56.5 2.9e-39 135.0 55.5 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 ORY01990.1 - 6.1e-22 77.8 28.2 1.9e-21 76.1 28.2 1.8 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 ORY01990.1 - 6.1e-14 51.7 7.5 6.1e-14 51.7 7.5 2.5 2 0 0 2 2 2 1 Sugar (and other) transporter Rax2 PF12768.7 ORY01991.1 - 8.3e-65 218.2 0.1 8.3e-65 218.2 0.1 3.3 3 1 0 4 4 4 1 Cortical protein marker for cell polarity fn3_3 PF14686.6 ORY01991.1 - 0.078 12.8 0.1 0.33 10.8 0.1 2.1 1 0 0 1 1 1 0 Polysaccharide lyase family 4, domain II Gmad1 PF10647.9 ORY01991.1 - 1.2 8.9 5.1 0.41 10.4 0.8 2.3 3 0 0 3 3 3 0 Lipoprotein LpqB beta-propeller domain Sec1 PF00995.23 ORY01992.1 - 4.9e-112 376.0 0.0 5.5e-112 375.9 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Vta1 PF04652.16 ORY01993.1 - 3.8e-49 166.4 6.3 3.8e-49 166.4 6.3 1.5 2 0 0 2 2 2 1 Vta1 like Vta1_C PF18097.1 ORY01993.1 - 1.4e-15 56.7 0.1 2.5e-15 55.9 0.1 1.5 1 0 0 1 1 1 1 Vta1 C-terminal domain Thioredoxin PF00085.20 ORY01994.1 - 4.5e-31 106.9 0.1 8.3e-25 86.8 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin OST3_OST6 PF04756.13 ORY01994.1 - 7.3e-08 32.1 0.0 7.4e-05 22.2 0.0 2.2 2 0 0 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 ORY01994.1 - 1.9e-06 28.3 1.0 0.085 13.3 0.1 2.9 1 1 1 2 2 2 2 Thioredoxin-like domain TraF PF13728.6 ORY01994.1 - 0.00025 21.0 7.9 0.0072 16.2 0.0 3.4 3 0 0 3 3 3 1 F plasmid transfer operon protein Thioredoxin_8 PF13905.6 ORY01994.1 - 0.022 15.0 0.1 5.6 7.4 0.0 3.3 2 1 1 3 3 3 0 Thioredoxin-like AhpC-TSA PF00578.21 ORY01994.1 - 0.052 13.5 0.0 0.21 11.5 0.0 1.9 2 0 0 2 2 2 0 AhpC/TSA family Thioredoxin_3 PF13192.6 ORY01994.1 - 0.056 13.5 0.2 16 5.6 0.1 2.5 2 0 0 2 2 2 0 Thioredoxin domain Calsequestrin PF01216.17 ORY01994.1 - 0.089 11.8 0.0 0.17 10.9 0.0 1.4 1 0 0 1 1 1 0 Calsequestrin Thioredoxin_7 PF13899.6 ORY01994.1 - 0.16 12.2 0.0 0.43 10.8 0.0 1.7 1 0 0 1 1 1 0 Thioredoxin-like Dynamin_M PF01031.20 ORY01995.1 - 1.2e-28 100.2 0.1 1.3e-20 73.8 0.0 2.7 2 0 0 2 2 2 2 Dynamin central region Dynamin_N PF00350.23 ORY01995.1 - 2.5e-26 92.7 1.1 5e-26 91.7 0.1 2.1 3 0 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.23 ORY01995.1 - 1.3e-05 25.2 0.7 8.4e-05 22.6 0.1 2.7 3 1 0 3 3 3 1 50S ribosome-binding GTPase GED PF02212.18 ORY01995.1 - 0.00022 21.3 1.9 0.00057 20.0 0.0 2.6 3 0 0 3 3 3 1 Dynamin GTPase effector domain LemA PF04011.12 ORY01995.1 - 0.022 14.6 0.5 0.092 12.6 0.1 2.3 2 0 0 2 2 2 0 LemA family AAA_16 PF13191.6 ORY01995.1 - 0.085 13.2 0.3 0.4 11.1 0.0 2.3 3 0 0 3 3 3 0 AAA ATPase domain OSK PF17182.4 ORY01998.1 - 0.1 11.8 0.0 0.14 11.4 0.0 1.1 1 0 0 1 1 1 0 OSK domain Ank_2 PF12796.7 ORY01999.1 - 2e-12 47.5 0.3 1.6e-05 25.4 0.0 3.8 2 1 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY01999.1 - 1.4e-05 25.5 0.1 0.26 11.9 0.0 4.1 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY01999.1 - 0.00012 22.2 0.6 26 5.8 0.0 6.8 7 0 0 7 7 7 1 Ankyrin repeat Ank_5 PF13857.6 ORY01999.1 - 0.0013 19.0 0.1 0.0076 16.5 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) LtrA PF06772.11 ORY02000.1 - 7.4e-29 101.1 18.7 7.4e-29 101.1 18.7 2.0 2 0 0 2 2 2 1 Bacterial low temperature requirement A protein (LtrA) Hum_adeno_E3A PF05393.11 ORY02000.1 - 8.4 6.4 7.9 2.8 8.0 0.0 3.8 5 0 0 5 5 5 0 Human adenovirus early E3A glycoprotein Fungal_trans PF04082.18 ORY02033.1 - 1.5e-41 142.2 0.0 2.6e-41 141.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Hemerythrin PF01814.23 ORY02035.1 - 1.5e-11 45.0 3.1 2.1e-11 44.6 3.1 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Dcc1 PF09724.9 ORY02036.1 - 1.3e-28 100.3 0.0 1.7e-28 99.9 0.0 1.0 1 0 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 RhoGEF PF00621.20 ORY02037.1 - 1.7e-21 77.3 0.3 4.9e-21 75.8 0.0 1.9 2 0 0 2 2 2 1 RhoGEF domain Nod1 PF17114.5 ORY02037.1 - 6.2e-08 32.9 0.0 1.6e-07 31.6 0.0 1.7 1 0 0 1 1 1 1 Gef2-related medial cortical node protein Nod1 Sugarporin_N PF11471.8 ORY02037.1 - 0.00067 19.6 1.7 0.002 18.0 1.7 1.8 1 0 0 1 1 1 1 Maltoporin periplasmic N-terminal extension DUF3507 PF12015.8 ORY02037.1 - 0.0037 17.0 0.0 0.0068 16.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3507) AD PF09793.9 ORY02037.1 - 0.32 11.2 1.8 4.7 7.4 0.0 3.4 4 0 0 4 4 4 0 Anticodon-binding domain Seryl_tRNA_N PF02403.22 ORY02037.1 - 2.5 8.4 13.6 3.8 7.8 6.1 2.8 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain HALZ PF02183.18 ORY02037.1 - 3.7 7.9 5.3 0.71 10.1 0.2 2.6 3 0 0 3 3 3 0 Homeobox associated leucine zipper Cpn60_TCP1 PF00118.24 ORY02038.1 - 5.3e-154 513.5 12.7 6.1e-154 513.3 12.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family ProRS-C_1 PF09180.11 ORY02039.1 - 4.9e-24 84.3 0.6 9.7e-24 83.4 0.6 1.5 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal HGTP_anticodon PF03129.20 ORY02039.1 - 1.9e-19 69.6 0.0 4.6e-19 68.4 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 ORY02039.1 - 5.4e-17 62.3 0.0 1e-16 61.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) C_Hendra PF16821.5 ORY02039.1 - 0.18 11.7 1.8 0.23 11.3 0.1 2.0 2 0 0 2 2 2 0 C protein from hendra and measles viruses PKI PF02827.16 ORY02039.1 - 0.66 10.2 3.3 2.3 8.5 2.8 2.2 2 0 0 2 2 2 0 cAMP-dependent protein kinase inhibitor RPN1_RPN2_N PF17781.1 ORY02040.1 - 5.1e-118 394.0 0.5 8.2e-118 393.3 0.5 1.3 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 ORY02040.1 - 1.1e-29 102.2 0.0 1.9e-29 101.5 0.0 1.4 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 ORY02040.1 - 1.7e-21 75.5 21.9 7.2e-06 26.2 0.4 8.7 8 0 0 8 8 8 4 Proteasome/cyclosome repeat HEAT_2 PF13646.6 ORY02040.1 - 6.4e-05 23.3 1.8 0.53 10.7 0.1 4.1 3 1 1 4 4 4 3 HEAT repeats RIO1 PF01163.22 ORY02041.1 - 2.2e-42 144.8 0.0 5e-42 143.6 0.0 1.5 1 1 0 1 1 1 1 RIO1 family Rio2_N PF09202.11 ORY02041.1 - 5.6e-31 106.6 0.0 1.3e-30 105.5 0.0 1.6 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.23 ORY02041.1 - 6.2e-08 32.9 0.1 0.0034 17.4 0.0 2.8 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 ORY02041.1 - 8.6e-06 25.2 0.1 0.0013 18.1 0.1 2.2 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4385 PF14328.6 ORY02042.1 - 2.2e-12 47.2 0.0 3.3e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4385) Glycos_transf_1 PF00534.20 ORY02043.1 - 7.9e-33 113.4 0.0 9.7e-32 109.9 0.0 2.1 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 ORY02043.1 - 2.3e-16 60.2 0.0 3.7e-16 59.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 ORY02043.1 - 2.7e-13 50.5 0.0 7.4e-13 49.1 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 ORY02043.1 - 1e-06 29.3 0.0 2.4e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain ALG11_N PF15924.5 ORY02043.1 - 0.0048 17.0 0.1 1.6 8.7 0.0 2.8 1 1 1 2 2 2 2 ALG11 mannosyltransferase N-terminus Glyco_trans_1_2 PF13524.6 ORY02043.1 - 0.0055 17.1 0.0 0.013 15.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Pkinase PF00069.25 ORY02044.1 - 1.1e-26 93.8 0.0 1.6e-26 93.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain HEAT PF02985.22 ORY02044.1 - 2.5e-11 42.8 6.0 0.05 13.9 0.0 7.1 7 0 0 7 7 7 3 HEAT repeat Pkinase_Tyr PF07714.17 ORY02044.1 - 1.1e-06 28.2 0.0 1.9e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase WD40 PF00400.32 ORY02044.1 - 3e-06 27.9 8.9 1e-05 26.2 0.1 5.5 5 1 1 6 6 6 1 WD domain, G-beta repeat HEAT_2 PF13646.6 ORY02044.1 - 1.9e-05 25.0 1.1 1 9.8 0.0 4.8 3 2 0 5 5 5 1 HEAT repeats Kinase-like PF14531.6 ORY02044.1 - 0.0037 16.6 0.0 0.0086 15.4 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Cnd1 PF12717.7 ORY02044.1 - 0.0071 16.4 0.3 9 6.3 0.0 3.2 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 ORY02044.1 - 0.022 15.2 0.4 26 5.5 0.0 3.7 4 0 0 4 4 4 0 HEAT-like repeat Ge1_WD40 PF16529.5 ORY02044.1 - 0.067 12.1 0.0 0.21 10.5 0.0 1.8 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein RTA1 PF04479.13 ORY02045.1 - 8.3e-69 231.3 12.7 1e-68 231.0 12.7 1.1 1 0 0 1 1 1 1 RTA1 like protein Abhydrolase_9_N PF15420.6 ORY02045.1 - 0.078 13.0 4.3 0.033 14.2 0.8 1.9 1 1 1 2 2 2 0 Alpha/beta-hydrolase family N-terminus PIG-P PF08510.12 ORY02045.1 - 0.96 9.4 7.0 4.9 7.1 1.0 2.7 2 0 0 2 2 2 0 PIG-P Statherin PF03875.13 ORY02046.1 - 0.033 14.3 2.1 3.7 7.7 0.7 2.4 2 0 0 2 2 2 0 Statherin Nucleoporin_FG PF13634.6 ORY02047.1 - 4.6e-19 69.1 87.8 1.4e-08 35.4 30.0 3.8 3 1 1 4 4 4 3 Nucleoporin FG repeat region MIP-T3_C PF17749.1 ORY02047.1 - 0.016 15.2 8.2 0.057 13.4 0.5 3.2 4 0 0 4 4 4 0 Microtubule-binding protein MIP-T3 C-terminal region DUF1664 PF07889.12 ORY02047.1 - 0.017 15.2 0.5 1.6 8.8 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) SKA1 PF07160.12 ORY02047.1 - 0.078 12.8 4.0 0.13 12.1 0.1 2.7 2 1 1 3 3 3 0 Spindle and kinetochore-associated protein 1 Fib_alpha PF08702.10 ORY02047.1 - 0.11 12.7 2.5 19 5.4 0.1 3.2 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Not3 PF04065.15 ORY02047.1 - 0.13 11.7 0.4 0.41 10.0 0.1 1.8 1 1 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component Fip1 PF05182.13 ORY02048.1 - 1.5e-19 69.3 0.7 2.9e-19 68.3 0.7 1.5 1 0 0 1 1 1 1 Fip1 motif TFIIF_alpha PF05793.12 ORY02048.1 - 8.1 4.9 8.3 11 4.4 8.3 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) LRR_9 PF14580.6 ORY02049.1 - 8.2e-43 145.9 0.0 1e-42 145.6 0.0 1.1 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 ORY02049.1 - 7.7e-10 38.9 5.7 5e-06 26.8 0.8 2.7 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY02049.1 - 2.9e-08 33.4 0.4 5.5e-08 32.5 0.1 1.7 2 0 0 2 2 2 1 Leucine rich repeat LRR_6 PF13516.6 ORY02049.1 - 0.17 12.0 0.3 40 4.6 0.1 3.6 4 0 0 4 4 4 0 Leucine Rich repeat GST_N_2 PF13409.6 ORY02051.1 - 4.6e-21 74.9 0.0 1.1e-20 73.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 ORY02051.1 - 1.4e-14 53.8 0.0 3.5e-14 52.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 ORY02051.1 - 4.9e-05 23.7 0.0 0.0013 19.1 0.0 2.6 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 ORY02051.1 - 0.00017 21.7 0.0 0.00037 20.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain zf-Di19 PF05605.12 ORY02052.1 - 0.035 14.4 0.2 0.062 13.6 0.2 1.4 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding FNIP_N PF14636.6 ORY02054.1 - 9.4e-28 98.1 0.0 9.4e-28 98.1 0.0 4.7 3 1 1 4 4 4 1 Folliculin-interacting protein N-terminus Corona_nucleoca PF00937.18 ORY02054.1 - 0.2 10.6 9.2 0.41 9.6 9.2 1.4 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein FNIP_M PF14637.6 ORY02054.1 - 0.25 11.3 0.1 0.5 10.3 0.1 1.4 1 0 0 1 1 1 0 Folliculin-interacting protein middle domain IML1 PF12257.8 ORY02057.1 - 5.6e-118 393.2 0.0 7.8e-118 392.7 0.0 1.2 1 0 0 1 1 1 1 Vacuolar membrane-associated protein Iml1 DEP PF00610.21 ORY02057.1 - 4.6e-28 97.1 0.7 8.8e-28 96.2 0.7 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) NAD_binding_10 PF13460.6 ORY02059.1 - 6.5e-19 68.5 0.0 3.2e-18 66.3 0.0 1.9 1 1 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 ORY02059.1 - 0.026 13.6 0.0 0.062 12.4 0.0 1.6 1 0 0 1 1 1 0 RmlD substrate binding domain Epimerase PF01370.21 ORY02059.1 - 0.034 13.6 0.0 0.06 12.8 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Ribosom_S12_S23 PF00164.25 ORY02061.1 - 3.5e-33 113.6 1.8 4.7e-33 113.2 1.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Ribosomal_S12 PF17487.2 ORY02061.1 - 0.17 12.6 0.0 0.37 11.5 0.0 1.5 1 1 0 1 1 1 0 Ribosomal protein S12 DUF4246 PF14033.6 ORY02063.1 - 1.6e-51 175.8 0.3 2.9e-41 142.0 0.0 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF4246) YcaO PF02624.16 ORY02063.1 - 0.057 12.7 0.2 0.34 10.2 0.0 1.9 2 0 0 2 2 2 0 YcaO cyclodehydratase, ATP-ad Mg2+-binding adh_short PF00106.25 ORY02065.1 - 1.1e-18 67.4 0.0 3.9e-16 59.1 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 ORY02065.1 - 1.2e-08 34.8 0.0 1.7e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY02065.1 - 0.0001 22.3 0.0 0.00018 21.4 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ORY02065.1 - 0.001 18.6 0.0 0.0013 18.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NMD3 PF04981.13 ORY02067.1 - 2.2e-77 259.8 0.2 3.1e-77 259.3 0.2 1.2 1 0 0 1 1 1 1 NMD3 family FYVE PF01363.21 ORY02067.1 - 0.83 9.8 3.9 6.3 7.0 1.2 2.6 2 1 0 2 2 2 0 FYVE zinc finger HypA PF01155.19 ORY02067.1 - 1 9.4 3.0 27 4.8 0.2 2.6 2 1 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Tnp_zf-ribbon_2 PF13842.6 ORY02067.1 - 1.2 10.0 5.7 1 10.2 0.3 2.9 3 0 0 3 3 3 0 DDE_Tnp_1-like zinc-ribbon DZR PF12773.7 ORY02067.1 - 2.7 8.1 8.2 1.6e+02 2.4 8.2 2.8 1 1 0 1 1 1 0 Double zinc ribbon RsfS PF02410.15 ORY02068.1 - 4.5e-13 49.5 0.0 1.2e-12 48.1 0.0 1.8 1 1 0 1 1 1 1 Ribosomal silencing factor during starvation Npa1 PF11707.8 ORY02070.1 - 1e-62 212.5 0.0 3.9e-62 210.6 0.0 1.9 2 0 0 2 2 2 1 Ribosome 60S biogenesis N-terminal NopRA1 PF16201.5 ORY02070.1 - 1.4e-57 194.6 0.0 2.9e-57 193.5 0.0 1.6 1 0 0 1 1 1 1 Nucleolar pre-ribosomal-associated protein 1 RasGEF PF00617.19 ORY02070.1 - 0.064 13.5 0.6 0.3 11.3 0.1 2.1 1 1 0 2 2 2 0 RasGEF domain APH PF01636.23 ORY02123.1 - 5.6e-05 23.2 0.1 0.0046 16.9 0.1 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 ORY02123.1 - 0.0013 18.4 0.2 0.0022 17.6 0.2 1.3 1 1 0 1 1 1 1 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 ORY02127.1 - 1.8e-12 46.8 7.7 1.1e-08 34.3 0.3 2.8 1 1 2 3 3 3 3 Fungal protein kinase Acetyltransf_13 PF13880.6 ORY02129.1 - 0.0042 17.0 0.2 0.021 14.8 0.1 2.2 2 1 1 3 3 3 1 ESCO1/2 acetyl-transferase Acetyltransf_1 PF00583.25 ORY02129.1 - 0.0046 17.2 0.0 0.019 15.2 0.0 1.8 1 1 1 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ORY02129.1 - 0.0087 16.5 0.0 0.024 15.1 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain PanZ PF12568.8 ORY02129.1 - 0.019 14.7 0.0 0.03 14.1 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_10 PF13673.7 ORY02129.1 - 0.03 14.2 0.0 0.069 13.1 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain TPR_8 PF13181.6 ORY02130.1 - 6.6e-05 22.8 0.0 0.31 11.4 0.0 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 ORY02130.1 - 0.00027 20.8 0.0 0.25 11.5 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat Choline_kinase PF01633.20 ORY02130.1 - 0.083 12.5 0.0 6.8 6.2 0.0 2.5 2 0 0 2 2 2 0 Choline/ethanolamine kinase TPR_1 PF00515.28 ORY02130.1 - 0.13 12.2 0.0 5.6 6.9 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_MalT PF17874.1 ORY02130.1 - 0.18 11.1 0.0 23 4.2 0.0 2.9 2 1 1 3 3 3 0 MalT-like TPR region RNA_helicase PF00910.22 ORY02131.1 - 0.0018 18.6 0.6 0.043 14.2 0.1 2.2 2 0 0 2 2 2 1 RNA helicase AAA PF00004.29 ORY02131.1 - 0.0026 18.2 0.2 0.007 16.8 0.2 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 ORY02131.1 - 0.049 13.1 0.0 0.086 12.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_28 PF13521.6 ORY02131.1 - 0.11 12.8 0.9 1.2 9.4 0.5 2.0 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 ORY02131.1 - 0.12 12.8 0.0 0.34 11.3 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain DTW PF03942.15 ORY02131.1 - 0.13 11.9 0.1 0.15 11.7 0.1 1.1 1 0 0 1 1 1 0 DTW domain AAA_22 PF13401.6 ORY02131.1 - 0.18 12.1 0.2 0.71 10.1 0.1 1.8 2 0 0 2 2 2 0 AAA domain Pkinase PF00069.25 ORY02134.1 - 0.059 12.7 0.1 0.067 12.5 0.1 1.3 1 1 0 1 1 1 0 Protein kinase domain p450 PF00067.22 ORY02167.1 - 4.2e-21 75.2 0.0 5.4e-21 74.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 NUDIX PF00293.28 ORY02168.1 - 2.1e-12 47.2 0.4 2.2e-11 43.9 0.1 2.2 1 1 2 3 3 3 1 NUDIX domain Bys1 PF04681.12 ORY02170.1 - 5e-06 26.5 0.1 5.9e-06 26.3 0.1 1.2 1 0 0 1 1 1 1 Blastomyces yeast-phase-specific protein SKG6 PF08693.10 ORY02171.1 - 0.0006 19.2 1.3 0.0013 18.1 1.3 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Podoplanin PF05808.11 ORY02171.1 - 0.00087 19.4 0.7 0.00087 19.4 0.7 2.1 2 0 0 2 2 2 1 Podoplanin DUF347 PF03988.12 ORY02171.1 - 0.011 15.9 0.1 0.018 15.2 0.1 1.3 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) Abhydrolase_6 PF12697.7 ORY02172.1 - 1.7e-11 45.1 0.0 2.1e-11 44.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family OrsD PF12013.8 ORY02173.1 - 2.6e-27 95.5 1.3 5.1e-27 94.6 0.5 1.9 2 0 0 2 2 2 1 Orsellinic acid/F9775 biosynthesis cluster protein D FOXP-CC PF16159.5 ORY02173.1 - 0.0045 17.6 1.1 0.013 16.1 0.1 2.3 2 0 0 2 2 2 1 FOXP coiled-coil domain Nepo_coat_C PF03688.14 ORY02173.1 - 0.021 14.7 0.0 0.13 12.2 0.0 2.2 1 1 0 1 1 1 0 Nepovirus coat protein, C-terminal domain SgrT PF15894.5 ORY02173.1 - 0.15 12.0 0.1 12 6.0 0.0 3.0 3 0 0 3 3 3 0 Inhibitor of glucose uptake transporter SgrT ADH_zinc_N PF00107.26 ORY02174.1 - 6.9e-11 42.2 0.8 1.3e-09 38.2 0.1 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ORY02174.1 - 3.7e-10 39.6 0.3 4.2e-09 36.2 0.2 2.3 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain SM-ATX PF14438.6 ORY02174.1 - 0.048 13.8 0.0 0.17 12.1 0.0 1.9 1 1 0 1 1 1 0 Ataxin 2 SM domain ADH_N_2 PF16884.5 ORY02174.1 - 0.094 12.6 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase TRI12 PF06609.13 ORY02176.1 - 2e-22 79.3 21.6 2.7e-22 79.0 21.6 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 ORY02176.1 - 1.5e-14 53.7 40.8 1.5e-14 53.7 40.8 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily Phage_holin_3_6 PF07332.11 ORY02176.1 - 0.27 11.3 0.1 0.27 11.3 0.1 5.3 3 2 2 5 5 5 0 Putative Actinobacterial Holin-X, holin superfamily III dCMP_cyt_deam_1 PF00383.23 ORY02177.1 - 2.7e-09 36.8 0.1 6.5e-09 35.6 0.1 1.7 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 ORY02177.1 - 0.00055 19.7 0.2 0.0059 16.4 0.0 2.1 2 0 0 2 2 2 1 MafB19-like deaminase ORC5_C PF14630.6 ORY02178.1 - 1.8e-63 214.7 0.0 2.9e-63 214.0 0.0 1.3 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.6 ORY02178.1 - 1.9e-15 57.7 0.0 4.5e-15 56.4 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 ORY02178.1 - 0.039 14.2 0.5 0.092 13.0 0.1 1.8 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.6 ORY02178.1 - 0.059 13.5 0.0 0.14 12.4 0.0 1.6 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 ORY02178.1 - 0.063 12.5 0.0 0.21 10.7 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain AAA_17 PF13207.6 ORY02179.1 - 0.045 14.2 0.5 0.084 13.3 0.0 1.6 2 0 0 2 2 2 0 AAA domain PQQ PF01011.21 ORY02179.1 - 0.19 11.7 0.5 10 6.2 0.2 2.6 2 0 0 2 2 2 0 PQQ enzyme repeat UPF0061 PF02696.14 ORY02181.1 - 8.5e-128 427.0 0.0 1.2e-127 426.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family CFEM PF05730.11 ORY02182.1 - 6.6e-06 26.1 13.3 9.9e-06 25.6 13.3 1.3 1 0 0 1 1 1 1 CFEM domain PTP_tm PF18861.1 ORY02182.1 - 0.00027 21.0 0.1 0.0006 19.9 0.1 1.6 1 0 0 1 1 1 1 Transmembrane domain of protein tyrosine phosphatase, receptor type J SKG6 PF08693.10 ORY02182.1 - 0.0075 15.7 3.6 0.02 14.3 3.6 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Rax2 PF12768.7 ORY02182.1 - 0.027 13.9 0.1 0.036 13.5 0.1 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity DUF3067 PF11267.8 ORY02183.1 - 0.18 12.4 0.0 0.35 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3067) DUF3291 PF11695.8 ORY02184.1 - 0.046 13.4 0.2 0.094 12.4 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3291) DUF4381 PF14316.6 ORY02186.1 - 0.073 13.3 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) TFIIS_M PF07500.14 ORY02186.1 - 0.5 10.9 1.9 2.2 8.8 0.5 2.6 2 1 1 3 3 3 0 Transcription factor S-II (TFIIS), central domain Haem_degrading PF03928.14 ORY02188.1 - 2.5e-28 98.5 0.1 3.3e-28 98.1 0.1 1.1 1 0 0 1 1 1 1 Haem-degrading Pyr_redox_2 PF07992.14 ORY02189.1 - 1.2e-09 37.9 0.0 6.2e-05 22.4 0.0 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ORY02189.1 - 1.7e-08 34.1 0.0 7.1e-06 25.5 0.0 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 ORY02189.1 - 6.5e-07 28.2 0.0 0.00022 19.8 0.0 2.6 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Shikimate_DH PF01488.20 ORY02189.1 - 2.7e-05 24.2 0.0 0.0055 16.8 0.0 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_8 PF13450.6 ORY02189.1 - 0.00079 19.6 0.1 0.0031 17.7 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 ORY02189.1 - 0.00098 18.3 0.1 0.0017 17.5 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain K_oxygenase PF13434.6 ORY02189.1 - 0.0078 15.4 0.0 2.6 7.1 0.0 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 ORY02189.1 - 0.011 15.3 1.7 0.8 9.2 0.4 2.8 3 0 0 3 3 3 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 ORY02189.1 - 0.036 14.5 0.1 4.5 7.8 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.19 ORY02189.1 - 0.085 12.2 1.1 0.11 11.8 0.0 1.8 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox PF00070.27 ORY02189.1 - 0.11 13.0 1.1 13 6.5 0.0 3.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 6PF2K PF01591.18 ORY02190.1 - 2e-73 246.4 0.1 1.1e-51 175.2 0.0 2.2 2 0 0 2 2 2 2 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 ORY02190.1 - 2e-29 102.7 0.1 2.4e-22 79.6 0.0 2.6 3 0 0 3 3 3 2 Histidine phosphatase superfamily (branch 1) Nudix_N PF12535.8 ORY02190.1 - 0.0077 15.8 0.1 0.029 14.0 0.0 2.0 2 0 0 2 2 2 1 Hydrolase of X-linked nucleoside diphosphate N terminal DUF2313 PF10076.9 ORY02190.1 - 0.059 13.2 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2313) KTI12 PF08433.10 ORY02190.1 - 0.091 12.2 0.0 0.44 9.9 0.0 1.9 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_33 PF13671.6 ORY02190.1 - 0.12 12.5 0.1 1.2 9.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF202 PF02656.15 ORY02192.1 - 0.02 15.4 8.5 0.13 12.7 8.5 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF202) Peptidase_M90 PF06167.12 ORY02192.1 - 0.034 13.8 0.0 0.046 13.3 0.0 1.2 1 0 0 1 1 1 0 Glucose-regulated metallo-peptidase M90 RNase_H PF00075.24 ORY02193.1 - 8.5e-33 113.5 0.0 1.7e-32 112.6 0.0 1.5 1 0 0 1 1 1 1 RNase H Cauli_VI PF01693.16 ORY02193.1 - 7.9e-32 109.3 11.1 3.2e-18 65.7 1.8 3.2 2 1 0 2 2 2 2 Caulimovirus viroplasmin FeThRed_A PF02941.15 ORY02194.1 - 0.038 14.1 0.0 0.054 13.6 0.0 1.2 1 0 0 1 1 1 0 Ferredoxin thioredoxin reductase variable alpha chain Sugar_tr PF00083.24 ORY02196.1 - 7e-59 199.9 35.0 1.2e-37 129.9 17.0 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 ORY02196.1 - 1.4e-05 24.2 48.0 0.0043 16.0 25.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_tran_28_C PF04101.16 ORY02200.1 - 0.028 14.4 0.4 0.045 13.7 0.1 1.4 2 0 0 2 2 2 0 Glycosyltransferase family 28 C-terminal domain EphA2_TM PF14575.6 ORY02200.1 - 0.057 14.3 0.0 0.089 13.7 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Fucose_iso_N2 PF07882.12 ORY02201.1 - 0.39 10.3 3.6 0.22 11.1 1.2 1.8 2 0 0 2 2 2 0 L-fucose isomerase, second N-terminal domain TPR_10 PF13374.6 ORY02205.1 - 6.3e-69 226.2 30.8 3.4e-11 42.6 0.1 8.4 7 1 0 7 7 7 7 Tetratricopeptide repeat TPR_12 PF13424.6 ORY02205.1 - 7.3e-60 199.2 33.1 2.3e-17 63.0 2.0 6.8 4 1 4 8 8 6 6 Tetratricopeptide repeat TPR_1 PF00515.28 ORY02205.1 - 4.6e-29 99.0 36.5 3.2e-05 23.6 0.2 8.5 7 1 0 7 7 7 5 Tetratricopeptide repeat TPR_7 PF13176.6 ORY02205.1 - 3.3e-26 89.4 17.5 0.0022 17.9 0.0 7.8 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_8 PF13181.6 ORY02205.1 - 3.5e-22 76.7 24.3 0.0018 18.3 0.1 7.7 7 1 0 7 7 7 5 Tetratricopeptide repeat Patatin PF01734.22 ORY02205.1 - 4.9e-21 75.9 0.0 1.4e-20 74.3 0.0 1.9 1 0 0 1 1 1 1 Patatin-like phospholipase TPR_2 PF07719.17 ORY02205.1 - 5.8e-21 72.9 31.9 0.0052 16.8 0.1 8.6 8 1 0 8 8 7 5 Tetratricopeptide repeat TPR_14 PF13428.6 ORY02205.1 - 1.4e-19 69.1 11.8 0.25 12.2 0.1 8.4 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_MalT PF17874.1 ORY02205.1 - 1.5e-19 70.6 13.5 3.8e-09 36.4 1.5 4.3 2 1 2 4 4 4 3 MalT-like TPR region TPR_17 PF13431.6 ORY02205.1 - 1.2e-12 47.3 17.9 0.2 12.1 0.1 7.6 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_4 PF07721.14 ORY02205.1 - 1.2e-12 47.2 0.9 1.3 9.8 0.0 7.4 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 ORY02205.1 - 1.7e-08 34.9 34.4 0.0017 19.0 3.8 7.8 6 2 0 7 7 5 3 Tetratricopeptide repeat PPR PF01535.20 ORY02205.1 - 7.8e-07 28.9 5.1 13 6.3 0.0 6.6 6 0 0 6 6 6 0 PPR repeat TPR_21 PF09976.9 ORY02205.1 - 6.7e-06 25.9 23.8 3.1 7.4 0.1 6.8 2 2 4 6 6 6 4 Tetratricopeptide repeat-like domain RPN7 PF10602.9 ORY02205.1 - 2.9e-05 23.8 7.7 3 7.5 0.1 5.8 3 1 4 7 7 6 1 26S proteasome subunit RPN7 AAA_16 PF13191.6 ORY02205.1 - 0.00012 22.5 0.1 0.0004 20.8 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain TPR_19 PF14559.6 ORY02205.1 - 0.00019 21.8 19.8 0.16 12.5 0.8 5.3 3 2 1 4 4 4 3 Tetratricopeptide repeat NB-ARC PF00931.22 ORY02205.1 - 0.00068 18.9 0.0 0.0019 17.5 0.0 1.7 1 0 0 1 1 1 1 NB-ARC domain ATPase_2 PF01637.18 ORY02205.1 - 0.00086 19.3 0.0 0.0019 18.2 0.0 1.6 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea SNAP PF14938.6 ORY02205.1 - 0.0017 17.8 3.5 0.29 10.5 0.1 3.3 2 1 1 3 3 3 2 Soluble NSF attachment protein, SNAP RPN6_N PF18055.1 ORY02205.1 - 0.037 14.4 6.0 32 4.9 0.1 5.0 1 1 5 6 6 6 0 26S proteasome regulatory subunit RPN6 N-terminal domain DUF1644 PF07800.12 ORY02205.1 - 0.044 13.8 0.0 0.095 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1644) DUF2225 PF09986.9 ORY02205.1 - 0.052 13.3 1.6 10 5.8 0.1 3.1 1 1 2 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) NACHT PF05729.12 ORY02205.1 - 0.076 12.9 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 NACHT domain TniB PF05621.11 ORY02205.1 - 0.1 12.0 0.0 0.22 10.9 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein AAA_22 PF13401.6 ORY02205.1 - 0.12 12.7 0.0 1 9.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain TPR_11 PF13414.6 ORY02205.1 - 0.12 12.1 37.7 0.75 9.5 0.8 7.2 7 0 0 7 7 7 0 TPR repeat RPN6_C_helix PF18503.1 ORY02205.1 - 0.43 10.3 13.0 62 3.5 0.1 6.2 6 0 0 6 6 6 0 26S proteasome subunit RPN6 C-terminal helix domain DUF4810 PF16068.5 ORY02205.1 - 1 10.0 13.6 25 5.5 0.1 5.8 6 0 0 6 6 5 0 Domain of unknown function (DUF4810) GTP_EFTU PF00009.27 ORY02255.1 - 2.3e-55 187.2 0.1 4.1e-55 186.3 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 ORY02255.1 - 6.1e-42 142.5 0.0 1.3e-41 141.4 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 ORY02255.1 - 3.5e-13 49.7 2.9 3.5e-13 49.7 2.9 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 ORY02255.1 - 0.00061 19.9 0.1 0.015 15.4 0.1 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase SLS PF14611.6 ORY02256.1 - 5.6e-31 108.1 0.0 8.4e-31 107.5 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial inner-membrane-bound regulator NT-C2 PF10358.9 ORY02258.1 - 3.5e-34 117.6 0.1 4.7e-34 117.2 0.1 1.2 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins A_deamin PF02137.18 ORY02259.1 - 8.5e-25 87.9 0.0 4e-23 82.4 0.0 2.0 2 0 0 2 2 2 2 Adenosine-deaminase (editase) domain Fungal_trans_2 PF11951.8 ORY02260.1 - 2.6e-15 56.2 0.0 7.7e-15 54.6 0.0 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY02260.1 - 0.00018 21.6 9.1 0.00042 20.4 9.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-RRPl_C4 PF17026.5 ORY02260.1 - 0.0047 17.0 1.5 0.0089 16.1 1.5 1.4 1 0 0 1 1 1 1 Putative ribonucleoprotein zinc-finger pf C4 type DUF4684 PF15736.5 ORY02260.1 - 0.097 11.3 1.2 0.16 10.6 1.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4684) DUF4805 PF16063.5 ORY02260.1 - 0.12 11.7 0.5 0.21 10.9 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4805) RhoGEF PF00621.20 ORY02261.1 - 2e-06 28.2 0.2 1.6e-05 25.2 0.0 2.6 2 0 0 2 2 2 1 RhoGEF domain Helo_like_N PF17111.5 ORY02261.1 - 0.0039 16.6 1.1 0.024 14.0 0.2 2.4 2 0 0 2 2 2 1 Fungal N-terminal domain of STAND proteins adh_short PF00106.25 ORY02262.1 - 1.1e-41 142.4 0.0 1.4e-41 142.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY02262.1 - 6.8e-41 140.3 0.1 1.8e-40 138.9 0.1 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY02262.1 - 0.00016 21.7 0.0 0.00024 21.1 0.0 1.2 1 0 0 1 1 1 1 KR domain Na_Ca_ex PF01699.24 ORY02263.1 - 5e-40 136.9 41.2 7.9e-22 77.8 17.7 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Red1 PF07964.11 ORY02263.1 - 0.13 10.5 7.5 0.18 10.0 7.5 1.1 1 0 0 1 1 1 0 Rec10 / Red1 SpoIIIAH PF12685.7 ORY02263.1 - 0.18 11.6 2.8 0.51 10.1 2.8 1.8 1 1 0 1 1 1 0 SpoIIIAH-like protein CRCB PF02537.15 ORY02263.1 - 0.2 12.0 5.0 0.88 9.9 4.9 2.2 1 1 0 1 1 1 0 CrcB-like protein, Camphor Resistance (CrcB) ATP-synt_8 PF00895.20 ORY02263.1 - 0.49 10.9 1.5 1.8 9.1 0.1 2.7 2 0 0 2 2 2 0 ATP synthase protein 8 Amidohydro_1 PF01979.20 ORY02264.1 - 7.6e-24 84.7 0.8 1.2e-23 84.0 0.8 1.3 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 ORY02264.1 - 2.4e-13 50.4 0.4 7.9e-09 35.5 0.1 2.2 2 0 0 2 2 2 2 Amidohydrolase family Fungal_trans_2 PF11951.8 ORY02265.1 - 8.3e-15 54.5 0.0 1.1e-14 54.0 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY02265.1 - 7.9e-10 38.7 13.4 1.5e-09 37.8 13.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SirB PF04247.12 ORY02265.1 - 0.16 12.1 0.1 0.33 11.0 0.1 1.5 1 0 0 1 1 1 0 Invasion gene expression up-regulator, SirB Polysacc_deac_1 PF01522.21 ORY02266.1 - 2.2e-25 89.0 0.0 2.9e-25 88.6 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 ORY02266.1 - 0.0023 17.2 0.0 0.0028 16.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 ADH_zinc_N PF00107.26 ORY02267.1 - 1.8e-11 44.1 0.2 3.1e-11 43.3 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ORY02267.1 - 0.00019 21.3 0.1 0.00037 20.3 0.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 ORY02267.1 - 0.031 15.3 0.0 0.075 14.1 0.0 1.7 1 1 0 1 1 1 0 Zinc-binding dehydrogenase HD PF01966.22 ORY02268.1 - 0.0047 17.1 0.0 0.0053 17.0 0.0 1.2 1 0 0 1 1 1 1 HD domain UPF0270 PF06794.12 ORY02269.1 - 0.14 12.2 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0270) Glyco_hydro_61 PF03443.14 ORY02272.1 - 2.7e-57 194.0 0.5 3.3e-57 193.7 0.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DDR PF08841.10 ORY02273.1 - 0.0073 15.3 0.1 0.012 14.6 0.1 1.2 1 0 0 1 1 1 1 Diol dehydratase reactivase ATPase-like domain HSP70 PF00012.20 ORY02273.1 - 0.13 10.4 0.0 0.19 9.9 0.0 1.2 1 0 0 1 1 1 0 Hsp70 protein TraL PF07178.11 ORY02274.1 - 0.04 14.4 0.0 0.16 12.5 0.0 1.9 2 0 0 2 2 2 0 TraL protein FeoB_associated PF12669.7 ORY02274.1 - 0.23 11.9 1.2 0.47 10.9 1.2 1.5 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein DUF5538 PF17692.1 ORY02275.1 - 0.04 14.0 0.8 0.04 14.0 0.8 2.3 2 1 1 3 3 3 0 Family of unknown function (DUF5538) HeLo PF14479.6 ORY02276.1 - 0.00017 21.5 0.0 0.0002 21.3 0.0 1.2 1 0 0 1 1 1 1 Prion-inhibition and propagation Nuc_deoxyri_tr2 PF15891.5 ORY02277.1 - 0.14 12.5 0.1 0.2 12.0 0.1 1.2 1 0 0 1 1 1 0 Nucleoside 2-deoxyribosyltransferase like Ras PF00071.22 ORY02278.1 - 2.5e-57 193.0 0.0 3.1e-57 192.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY02278.1 - 1.5e-34 118.8 0.0 2.2e-34 118.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY02278.1 - 1e-13 51.1 0.0 2e-13 50.2 0.0 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 ORY02278.1 - 7.9e-06 25.5 0.0 1.7e-05 24.4 0.0 1.4 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 ORY02278.1 - 1.8e-05 24.2 0.0 2.3e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 ORY02278.1 - 2.1e-05 24.6 0.0 3e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 ORY02278.1 - 0.00013 22.4 0.3 0.00017 22.0 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 ORY02278.1 - 0.0026 17.7 0.0 1.2 9.1 0.0 2.8 2 1 0 2 2 2 2 RsgA GTPase TniB PF05621.11 ORY02278.1 - 0.14 11.6 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein Fungal_trans_2 PF11951.8 ORY02280.1 - 2.7e-10 39.6 0.0 4.5e-10 38.9 0.0 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain TFIIS_C PF01096.18 ORY02282.1 - 7.2e-18 64.2 3.1 7.2e-18 64.2 3.1 2.6 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 ORY02282.1 - 2.5e-07 30.4 2.9 0.013 15.4 0.1 3.2 3 0 0 3 3 3 2 RNA polymerases M/15 Kd subunit zf-Mss51 PF13824.6 ORY02282.1 - 0.12 12.4 2.8 0.59 10.3 0.2 2.2 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-ZPR1 PF03367.13 ORY02282.1 - 0.31 10.9 3.2 3.8 7.3 0.1 2.1 2 0 0 2 2 2 0 ZPR1 zinc-finger domain C1_4 PF07975.12 ORY02282.1 - 0.42 10.9 6.0 6.7 7.0 0.4 2.9 2 2 1 3 3 3 0 TFIIH C1-like domain zf-C3HC PF07967.13 ORY02282.1 - 0.7 9.9 8.1 11 6.1 0.3 2.8 1 1 1 2 2 2 0 C3HC zinc finger-like Ank_3 PF13606.6 ORY02283.1 - 4.4e-09 35.8 0.3 0.0064 16.9 0.0 4.2 3 1 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 ORY02283.1 - 2.1e-08 34.2 0.7 0.00083 19.6 0.1 3.6 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 ORY02283.1 - 1.1e-06 28.8 0.0 0.059 13.9 0.0 2.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 ORY02283.1 - 1.1e-06 29.1 0.0 1e-05 26.0 0.0 2.4 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY02283.1 - 4.9e-06 27.0 0.0 0.00022 21.7 0.0 2.8 3 0 0 3 3 3 1 Ankyrin repeats (many copies) SF3b10 PF07189.11 ORY02284.1 - 9e-38 128.3 0.0 1e-37 128.1 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) bZIP_C PF12498.8 ORY02286.1 - 0.47 11.4 2.0 0.8 10.7 2.0 1.3 1 0 0 1 1 1 0 Basic leucine-zipper C terminal Abhydrolase_1 PF00561.20 ORY02287.1 - 3.3e-12 46.6 0.0 3.2e-08 33.5 0.1 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORY02287.1 - 1.4e-11 45.5 4.4 1.6e-10 42.0 4.4 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORY02287.1 - 2.2e-07 30.4 0.0 8.2e-07 28.5 0.0 1.9 2 0 0 2 2 2 1 Serine aminopeptidase, S33 EHN PF06441.12 ORY02287.1 - 0.051 14.0 0.0 0.1 12.9 0.0 1.4 1 0 0 1 1 1 0 Epoxide hydrolase N terminus APH PF01636.23 ORY02288.1 - 4.2e-14 53.0 0.0 7.7e-14 52.2 0.0 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 ORY02288.1 - 0.014 15.0 0.0 0.028 14.0 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Choline_kinase PF01633.20 ORY02288.1 - 0.079 12.5 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Homeobox_KN PF05920.11 ORY02289.1 - 3.3e-16 58.9 0.2 6.9e-16 57.9 0.2 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 ORY02289.1 - 1.7e-10 40.6 0.0 5.6e-10 38.9 0.0 1.8 1 0 0 1 1 1 1 Homeodomain Fungal_trans PF04082.18 ORY02290.1 - 5.9e-23 81.2 0.4 2e-22 79.5 0.1 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain CoA_transf_3 PF02515.17 ORY02291.1 - 3.9e-39 134.8 0.1 7.7e-38 130.6 0.0 2.5 3 0 0 3 3 3 2 CoA-transferase family III 7TM_GPCR_Srv PF10323.9 ORY02292.1 - 0.047 13.0 0.8 0.08 12.3 0.1 1.6 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srv DUF1345 PF07077.11 ORY02292.1 - 0.083 12.6 0.4 0.16 11.7 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1345) DUF3262 PF11660.8 ORY02292.1 - 0.65 10.4 4.3 0.2 12.1 0.3 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3262) DctQ PF04290.12 ORY02292.1 - 0.78 9.7 7.6 0.17 11.8 1.0 2.6 3 0 0 3 3 3 0 Tripartite ATP-independent periplasmic transporters, DctQ component DUF3021 PF11457.8 ORY02292.1 - 0.95 9.8 5.7 0.36 11.2 0.3 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3021) DUF805 PF05656.14 ORY02293.1 - 8.8 6.8 6.9 32 5.0 6.8 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF805) RelA_SpoT PF04607.17 ORY02294.1 - 1.3e-10 41.6 0.5 6.6e-09 36.1 0.5 2.5 1 1 0 1 1 1 1 Region found in RelA / SpoT proteins Gp_dh_C PF02800.20 ORY02294.1 - 0.13 11.8 0.4 0.23 11.1 0.4 1.4 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain CorA PF01544.18 ORY02295.1 - 2.1e-09 37.1 0.1 3.2e-09 36.5 0.1 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Nod1 PF17114.5 ORY02295.1 - 0.054 13.6 0.1 0.11 12.6 0.1 1.5 1 0 0 1 1 1 0 Gef2-related medial cortical node protein Nod1 Not3 PF04065.15 ORY02295.1 - 0.16 11.4 0.1 0.24 10.8 0.1 1.1 1 0 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component HOOK PF05622.12 ORY02348.1 - 0.051 11.7 0.4 0.087 11.0 0.4 1.3 1 0 0 1 1 1 0 HOOK protein NAD_binding_10 PF13460.6 ORY02349.1 - 1.7e-15 57.4 0.0 2.3e-15 57.0 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 ORY02349.1 - 2.8e-07 30.3 0.0 3.8e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 ORY02349.1 - 2.6e-05 23.8 0.0 3.5e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.25 ORY02349.1 - 0.032 13.7 0.0 0.044 13.2 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase GDP_Man_Dehyd PF16363.5 ORY02349.1 - 0.096 12.1 0.0 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 ORY02349.1 - 0.18 10.9 0.0 0.24 10.5 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein HSP70 PF00012.20 ORY02350.1 - 7.4e-13 47.5 0.0 1.3e-12 46.7 0.0 1.4 1 1 0 1 1 1 1 Hsp70 protein AIG1 PF04548.16 ORY02351.1 - 6.1e-07 29.0 0.0 1.1e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.23 ORY02351.1 - 2.8e-06 27.4 0.0 5.1e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.18 ORY02351.1 - 3.2e-06 26.6 0.0 4.9e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Septin RsgA_GTPase PF03193.16 ORY02351.1 - 3.7e-05 23.7 0.1 8e-05 22.6 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase Dynamin_N PF00350.23 ORY02351.1 - 0.003 17.6 4.0 0.99 9.4 0.1 2.9 2 1 1 3 3 3 2 Dynamin family AAA_22 PF13401.6 ORY02351.1 - 0.032 14.5 0.0 0.072 13.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain GBP PF02263.19 ORY02351.1 - 0.062 12.6 0.1 0.13 11.5 0.0 1.4 1 1 0 1 1 1 0 Guanylate-binding protein, N-terminal domain AAA_16 PF13191.6 ORY02351.1 - 0.063 13.7 0.1 0.42 11.0 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain DUF87 PF01935.17 ORY02351.1 - 0.12 12.4 0.1 0.32 11.0 0.1 1.7 1 0 0 1 1 1 0 Helicase HerA, central domain IGFL PF14653.6 ORY02351.1 - 0.14 12.2 0.3 1.1 9.2 0.0 2.1 2 0 0 2 2 2 0 Insulin growth factor-like family UPF0242 PF06785.11 ORY02352.1 - 0.036 14.2 0.1 0.059 13.5 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus CC2-LZ PF16516.5 ORY02352.1 - 0.04 14.3 0.5 0.082 13.3 0.5 1.5 1 0 0 1 1 1 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Geminin PF07412.12 ORY02352.1 - 0.15 11.8 3.0 0.27 11.0 3.0 1.3 1 0 0 1 1 1 0 Geminin Cep57_CLD_2 PF14197.6 ORY02352.1 - 0.29 11.2 5.0 0.38 10.9 3.9 1.7 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 Methyltransf_2 PF00891.18 ORY02353.1 - 2.7e-20 72.6 0.0 4.2e-20 72.0 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 ORY02353.1 - 0.033 14.2 0.0 0.077 13.0 0.0 1.6 1 0 0 1 1 1 0 Dimerisation domain Inhibitor_I66 PF16850.5 ORY02354.1 - 0.098 12.5 0.1 0.15 11.9 0.1 1.2 1 0 0 1 1 1 0 Peptidase inhibitor I66 Methyltransf_2 PF00891.18 ORY02356.1 - 4.4e-24 84.9 0.0 6.5e-24 84.4 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain AMP-binding PF00501.28 ORY02357.1 - 5.3e-53 180.1 0.0 7.6e-53 179.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Thioesterase PF00975.20 ORY02357.1 - 1e-24 88.0 0.0 1.8e-24 87.2 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain PP-binding PF00550.25 ORY02357.1 - 3.9e-11 43.1 0.0 8.7e-11 42.0 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Tim54 PF11711.8 ORY02358.1 - 7.1e-146 485.8 1.0 7.1e-146 485.8 1.0 1.9 2 0 0 2 2 2 1 Inner membrane protein import complex subunit Tim54 Pre-PUA PF17832.1 ORY02359.1 - 1e-25 90.2 0.6 1.3e-25 89.9 0.6 1.2 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 ORY02359.1 - 1.3e-13 50.7 0.3 1.7e-12 47.1 0.3 2.1 1 1 0 1 1 1 1 PUA domain DUF1947 PF09183.10 ORY02359.1 - 0.0035 17.6 0.1 0.0063 16.8 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1947) Argos PF11581.8 ORY02360.1 - 0.2 11.7 0.5 2.2 8.3 0.2 2.0 1 1 1 2 2 2 0 Antagonist of EGFR signalling, Argos Vut_1 PF02592.15 ORY02361.1 - 0.018 15.4 0.4 0.096 13.0 0.0 2.2 2 0 0 2 2 2 0 Putative vitamin uptake transporter Band_7 PF01145.25 ORY02363.1 - 3.2e-30 105.4 0.5 6.2e-30 104.5 0.5 1.5 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_C PF16200.5 ORY02363.1 - 1.9e-23 82.3 1.2 5.6e-23 80.8 1.2 1.9 1 0 0 1 1 1 1 C-terminal region of band_7 Pox_A11 PF05061.13 ORY02363.1 - 0.035 13.4 0.6 0.054 12.8 0.6 1.3 1 0 0 1 1 1 0 Poxvirus A11 Protein F-box-like PF12937.7 ORY02370.1 - 7.3e-05 22.6 0.0 0.00017 21.4 0.0 1.7 1 0 0 1 1 1 1 F-box-like CFEM PF05730.11 ORY02371.1 - 0.00014 21.9 6.0 0.00014 21.9 6.0 1.7 2 0 0 2 2 2 1 CFEM domain SWI-SNF_Ssr4 PF08549.10 ORY02371.1 - 0.4 9.3 5.3 0.47 9.0 5.3 1.0 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) p450 PF00067.22 ORY02372.1 - 1.3e-76 258.2 0.0 1.7e-76 257.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.20 ORY02372.1 - 2.3e-33 115.6 0.0 4.2e-33 114.8 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 ORY02372.1 - 9.6e-27 93.9 0.0 2e-26 92.9 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 ORY02372.1 - 1.7e-12 47.9 0.0 6e-12 46.2 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 ORY02372.1 - 0.0048 17.1 0.0 0.012 15.8 0.0 1.7 1 0 0 1 1 1 1 Flavodoxin domain MATalpha_HMGbox PF04769.12 ORY02374.1 - 0.076 12.3 0.1 0.11 11.7 0.1 1.2 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 HMG-box NPR3 PF03666.13 ORY02375.1 - 4.1e-136 454.5 0.1 4.4e-135 451.1 0.0 2.2 2 0 0 2 2 2 1 Nitrogen Permease regulator of amino acid transport activity 3 Dicty_REP PF05086.12 ORY02375.1 - 2 6.3 3.8 3.4 5.5 3.8 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein tRNA_lig_CPD PF08302.11 ORY02376.1 - 3e-85 285.7 0.0 6.5e-85 284.6 0.0 1.5 2 0 0 2 2 2 1 Fungal tRNA ligase phosphodiesterase domain RNA_lig_T4_1 PF09511.10 ORY02376.1 - 3e-83 279.0 0.0 5.2e-83 278.2 0.0 1.4 1 0 0 1 1 1 1 RNA ligase tRNA_lig_kinase PF08303.11 ORY02376.1 - 2.5e-53 180.6 0.6 2e-52 177.7 0.0 2.2 2 0 0 2 2 2 1 tRNA ligase kinase domain DUF1990 PF09348.10 ORY02376.1 - 0.016 15.2 0.0 2.1 8.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1990) AAA_18 PF13238.6 ORY02376.1 - 0.045 14.3 0.0 0.19 12.3 0.0 2.2 1 0 0 1 1 1 0 AAA domain dNK PF01712.19 ORY02376.1 - 0.062 13.1 0.0 0.26 11.1 0.0 2.0 1 1 1 2 2 2 0 Deoxynucleoside kinase DUF1653 PF07866.11 ORY02376.1 - 0.078 13.3 0.0 0.21 11.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1653) HgmA PF04209.13 ORY02377.1 - 1.5e-164 547.8 0.0 1.7e-164 547.5 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase Got1 PF04178.12 ORY02378.1 - 3.3e-30 104.8 13.2 6.6e-30 103.8 13.2 1.5 1 1 0 1 1 1 1 Got1/Sft2-like family HLH PF00010.26 ORY02380.1 - 6.4e-12 45.2 0.0 2.5e-11 43.4 0.0 1.9 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain CHCH PF06747.13 ORY02381.1 - 3.2e-05 23.9 0.3 4.8e-05 23.4 0.3 1.3 1 0 0 1 1 1 1 CHCH domain Pet191_N PF10203.9 ORY02381.1 - 0.0056 16.9 1.4 0.019 15.3 1.4 1.8 1 1 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 CX9C PF16860.5 ORY02381.1 - 0.073 13.1 0.2 0.13 12.3 0.2 1.5 1 1 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, COX17 PF05051.13 ORY02381.1 - 0.26 11.7 1.4 2.6 8.4 0.2 2.1 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) DUF2828 PF11443.8 ORY02442.1 - 5.3e-238 791.2 1.6 8.5e-238 790.6 1.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2828) zf-ANAPC11 PF12861.7 ORY02443.1 - 2.2e-43 146.2 8.5 2.9e-43 145.8 8.5 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 ORY02443.1 - 1.3e-22 79.8 12.0 2.5e-22 78.9 12.0 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 ORY02443.1 - 8.9e-08 32.3 14.8 5e-07 29.9 14.8 2.0 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 ORY02443.1 - 2.2e-06 27.4 11.5 5.7e-06 26.1 11.5 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORY02443.1 - 5.7e-05 23.1 11.2 0.0007 19.6 7.5 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 ORY02443.1 - 0.00052 19.8 8.6 0.00052 19.8 8.6 2.6 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORY02443.1 - 0.0011 18.8 13.9 0.0054 16.7 13.9 2.0 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 ORY02443.1 - 0.0029 17.4 12.2 0.25 11.2 12.5 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 ORY02443.1 - 0.0088 15.6 6.1 0.0088 15.6 6.1 1.9 1 1 1 2 2 2 1 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.6 ORY02443.1 - 0.0088 16.2 4.8 0.0088 16.2 4.8 2.1 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 ORY02443.1 - 0.011 15.5 11.1 0.36 10.6 8.4 2.6 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain Rad50_zn_hook PF04423.14 ORY02443.1 - 0.028 14.2 0.1 0.028 14.2 0.1 1.7 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-RING-like PF08746.11 ORY02443.1 - 0.049 14.0 8.1 0.049 14.0 8.1 1.7 2 1 0 2 2 1 0 RING-like domain zf-HIT PF04438.16 ORY02443.1 - 0.069 13.0 9.3 0.09 12.7 3.9 2.3 2 0 0 2 2 2 0 HIT zinc finger FANCL_C PF11793.8 ORY02443.1 - 0.085 13.1 13.6 0.69 10.1 13.6 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain zf-Nse PF11789.8 ORY02443.1 - 0.17 11.7 9.7 0.065 13.1 6.5 2.1 2 1 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_11 PF17123.5 ORY02443.1 - 0.18 11.6 13.2 0.5 10.2 10.1 2.8 2 1 0 2 2 2 0 RING-like zinc finger RecR PF02132.15 ORY02443.1 - 0.63 9.7 9.0 0.67 9.6 0.3 3.1 3 0 0 3 3 3 0 RecR protein RINGv PF12906.7 ORY02443.1 - 0.87 9.8 12.9 4.9 7.4 12.9 2.1 1 1 0 1 1 1 0 RING-variant domain DZR PF12773.7 ORY02443.1 - 7.8 6.6 13.9 1.4e+03 -0.6 13.5 2.5 1 1 0 1 1 1 0 Double zinc ribbon Rhodanese PF00581.20 ORY02444.1 - 4.9e-19 68.8 0.0 1.2e-11 45.0 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain DUF2076 PF09849.9 ORY02445.1 - 1.3e-08 35.2 15.2 1.8e-08 34.8 15.2 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.13 ORY02445.1 - 9.3e-05 22.5 0.9 0.0017 18.4 1.9 2.1 1 1 1 2 2 2 2 CHCH domain CX9C PF16860.5 ORY02445.1 - 0.0019 18.2 0.3 0.0029 17.6 0.3 1.2 1 0 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, ApbA_C PF08546.11 ORY02446.1 - 1.4e-31 109.2 0.1 2.2e-31 108.6 0.1 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 ORY02446.1 - 3.2e-20 72.3 0.0 5.3e-19 68.3 0.0 2.1 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Sas10_Utp3 PF04000.15 ORY02447.1 - 1e-14 54.9 0.1 1.3e-14 54.5 0.1 1.1 1 0 0 1 1 1 1 Sas10/Utp3/C1D family Aminotran_3 PF00202.21 ORY02448.1 - 4.2e-42 144.2 0.4 2.6e-26 92.2 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-III adh_short PF00106.25 ORY02449.1 - 8.9e-27 93.8 0.0 1.4e-26 93.2 0.0 1.3 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY02449.1 - 1.4e-21 77.2 0.0 1.9e-21 76.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY02449.1 - 3.7e-12 46.5 0.1 5e-12 46.1 0.1 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 ORY02449.1 - 1.9e-07 30.5 0.0 2.5e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 ORY02449.1 - 1.3e-06 28.1 0.1 4.5e-06 26.3 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family TetR_C_16 PF17920.1 ORY02449.1 - 0.0011 19.2 0.0 0.0072 16.5 0.0 2.3 3 0 0 3 3 3 1 Tetracyclin repressor-like, C-terminal domain GDP_Man_Dehyd PF16363.5 ORY02449.1 - 0.033 13.6 0.0 0.05 13.0 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Eno-Rase_NADH_b PF12242.8 ORY02449.1 - 0.035 13.9 0.0 0.093 12.5 0.1 1.7 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase RmlD_sub_bind PF04321.17 ORY02449.1 - 0.091 11.8 0.0 0.16 11.1 0.0 1.5 1 0 0 1 1 1 0 RmlD substrate binding domain CAP59_mtransfer PF11735.8 ORY02450.1 - 3e-68 230.1 0.0 3.5e-66 223.3 0.0 2.1 1 1 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Phage-tail_3 PF13550.6 ORY02450.1 - 0.058 13.2 0.0 0.21 11.5 0.0 1.8 1 1 1 2 2 2 0 Putative phage tail protein Chromate_transp PF02417.15 ORY02451.1 - 9.4e-59 198.0 37.6 3.3e-33 115.1 14.0 2.6 3 0 0 3 3 3 2 Chromate transporter Acetyltransf_10 PF13673.7 ORY02452.1 - 7.6e-10 38.8 0.0 1.1e-09 38.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORY02452.1 - 6.3e-09 36.1 0.0 9.1e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 ORY02452.1 - 9.8e-08 31.9 0.0 1.6e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 ORY02452.1 - 5.1e-05 23.6 0.0 7.8e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 ORY02452.1 - 0.00027 21.0 0.0 0.0004 20.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 ORY02452.1 - 0.092 12.9 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PAS_9 PF13426.7 ORY02453.1 - 3.1e-14 53.1 0.0 1.4e-11 44.5 0.0 2.6 2 0 0 2 2 2 2 PAS domain DUF2336 PF10098.9 ORY02453.1 - 0.11 12.0 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2336) PQ-loop PF04193.14 ORY02455.1 - 2.8e-36 123.1 12.2 3.3e-18 65.2 4.0 2.5 2 0 0 2 2 2 2 PQ loop repeat RRN9 PF10680.9 ORY02459.1 - 4.5e-13 49.3 6.0 5.3e-13 49.1 3.2 2.7 2 1 0 2 2 2 1 RNA polymerase I specific transcription initiation factor IBR PF01485.21 ORY02460.1 - 4.1e-19 68.5 23.1 6.3e-11 42.3 9.3 3.9 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain HscB_4_cys PF18256.1 ORY02460.1 - 2.8 7.8 7.9 25 4.8 0.1 3.9 3 0 0 3 3 3 0 Co-chaperone HscB tetracysteine metal binding motif OrfB_Zn_ribbon PF07282.11 ORY02460.1 - 6.8 6.7 22.6 1.3 9.0 4.6 3.6 3 0 0 3 3 3 0 Putative transposase DNA-binding domain F-box-like PF12937.7 ORY02461.1 - 4.3e-06 26.5 1.6 7.4e-06 25.8 0.1 2.1 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 ORY02461.1 - 0.00014 22.2 4.5 0.62 10.6 0.0 4.4 3 1 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 ORY02461.1 - 0.018 15.0 5.7 1.2 9.4 0.1 4.0 4 0 0 4 4 4 0 Leucine Rich repeat F-box PF00646.33 ORY02461.1 - 0.019 14.8 1.7 0.05 13.5 0.0 2.5 3 0 0 3 3 3 0 F-box domain LRR_8 PF13855.6 ORY02461.1 - 0.092 12.5 4.4 6.3 6.7 0.3 4.1 4 1 0 4 4 4 0 Leucine rich repeat DUF4079 PF13301.6 ORY02462.1 - 9.1 6.4 7.6 9 6.4 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF4079) NnrU PF07298.11 ORY02463.1 - 0.13 11.8 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 NnrU protein Kelch_4 PF13418.6 ORY02464.1 - 5.2e-17 61.6 0.1 1.4e-06 28.2 0.0 4.9 4 1 0 4 4 4 2 Galactose oxidase, central domain Kelch_3 PF13415.6 ORY02464.1 - 2.9e-15 56.1 5.1 2.4e-10 40.4 0.0 4.9 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_5 PF13854.6 ORY02464.1 - 4.5e-14 52.1 0.5 4.2e-05 23.4 0.1 4.0 3 1 0 3 3 3 2 Kelch motif Kelch_1 PF01344.25 ORY02464.1 - 6.3e-13 48.1 0.0 0.00089 18.8 0.0 4.0 3 1 0 3 3 3 3 Kelch motif Kelch_6 PF13964.6 ORY02464.1 - 1.2e-09 38.1 3.5 0.014 15.6 0.0 5.5 3 1 1 4 4 4 2 Kelch motif Kelch_2 PF07646.15 ORY02464.1 - 4.1e-07 29.7 0.3 0.00021 21.1 0.0 4.2 3 1 0 3 3 3 1 Kelch motif BTB PF00651.31 ORY02464.1 - 0.034 14.4 0.0 0.15 12.3 0.1 1.9 2 0 0 2 2 2 0 BTB/POZ domain AhpC-TSA PF00578.21 ORY02465.1 - 1.8e-30 105.4 0.0 2.4e-30 105.0 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 ORY02465.1 - 2.5e-11 43.5 0.0 3.6e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 ORY02465.1 - 3.1e-10 39.7 0.1 6.3e-10 38.7 0.1 1.6 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin MFS_1 PF07690.16 ORY02466.1 - 2.9e-39 135.0 34.6 2.9e-39 135.0 34.6 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 ORY02466.1 - 2.8e-08 32.7 8.5 5.4e-08 31.7 8.5 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 ORY02466.1 - 1.8e-05 23.8 18.8 1.8e-05 23.8 18.8 2.8 2 2 0 2 2 2 1 Sugar (and other) transporter PQ-loop PF04193.14 ORY02467.1 - 4.8e-20 71.1 7.7 2.8e-11 43.0 3.0 2.5 2 0 0 2 2 2 2 PQ loop repeat Sugar_tr PF00083.24 ORY02468.1 - 2.4e-116 389.3 20.5 2.8e-116 389.1 20.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY02468.1 - 1.9e-20 73.1 27.6 1.9e-20 73.1 27.6 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_5 PF05631.14 ORY02468.1 - 0.00016 20.8 1.1 0.00016 20.8 1.1 1.7 2 0 0 2 2 2 1 Sugar-tranasporters, 12 TM TRI12 PF06609.13 ORY02468.1 - 0.0013 17.3 1.0 0.0025 16.3 1.0 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2264 PF10022.9 ORY02469.1 - 2.1e-139 464.6 1.2 2.5e-139 464.3 1.2 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) RPEL PF02755.15 ORY02470.1 - 9.5e-34 114.1 10.1 6.9e-11 41.5 0.3 3.6 3 0 0 3 3 3 3 RPEL repeat DUF5538 PF17692.1 ORY02471.1 - 0.047 13.8 0.5 0.052 13.6 0.5 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5538) Bac_rhodopsin PF01036.18 ORY02472.1 - 1.8e-49 168.4 18.5 2e-49 168.2 18.5 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein Heliorhodopsin PF18761.1 ORY02472.1 - 0.006 15.9 14.7 0.0094 15.3 13.3 1.9 1 1 1 2 2 2 1 Heliorhodopsin DUF21 PF01595.20 ORY02472.1 - 0.011 15.5 6.8 0.05 13.3 2.1 2.2 2 0 0 2 2 2 0 Cyclin M transmembrane N-terminal domain SLATT_fungal PF18142.1 ORY02472.1 - 0.013 15.4 0.3 0.088 12.8 0.0 2.0 1 1 1 2 2 2 0 SMODS and SLOG-associating 2TM effector domain MerC PF03203.14 ORY02472.1 - 0.29 11.6 13.9 0.86 10.1 8.0 2.4 2 0 0 2 2 2 0 MerC mercury resistance protein DUF4131 PF13567.6 ORY02472.1 - 0.74 9.5 4.8 2.5 7.7 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) TssN PF17555.2 ORY02472.1 - 1.4 8.2 6.6 0.2 11.0 0.6 2.0 2 0 0 2 2 2 0 Type VI secretion system, TssN DUF4381 PF14316.6 ORY02472.1 - 1.8 8.8 5.3 0.91 9.8 0.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) TMEM208_SND2 PF05620.11 ORY02472.1 - 1.9 8.2 6.2 0.91 9.3 0.1 2.8 3 0 0 3 3 3 0 SRP-independent targeting protein 2/TMEM208 DUF1129 PF06570.11 ORY02472.1 - 2.8 7.4 7.7 1.3 8.5 1.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) DUF3810 PF12725.7 ORY02472.1 - 3.5 6.9 9.1 4.3 6.6 1.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) Zip PF02535.22 ORY02474.1 - 3.2e-68 230.4 2.1 3.6e-68 230.3 2.1 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter Polyketide_cyc2 PF10604.9 ORY02475.1 - 7.2e-06 26.3 0.1 3.4e-05 24.1 0.1 1.9 2 0 0 2 2 2 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 ORY02475.1 - 0.034 14.4 0.0 0.045 13.9 0.0 1.3 1 0 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport Shadoo PF14999.6 ORY02476.1 - 0.4 10.8 11.7 0.038 14.1 6.4 2.0 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective IMS PF00817.20 ORY02478.1 - 1.8e-41 141.7 0.2 3.1e-41 140.9 0.2 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 ORY02478.1 - 3e-14 53.7 0.1 8.5e-14 52.3 0.1 1.7 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 ORY02478.1 - 0.00042 20.5 0.0 0.001 19.3 0.0 1.7 1 0 0 1 1 1 1 IMS family HHH motif Vps36-NZF-N PF16988.5 ORY02478.1 - 5 6.6 8.6 24 4.4 5.4 3.1 2 1 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Pil1 PF13805.6 ORY02479.1 - 3.5e-128 426.7 0.4 4.4e-128 426.3 0.4 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 FAM92 PF06730.11 ORY02479.1 - 0.095 12.1 3.4 0.08 12.3 1.2 1.8 1 1 1 2 2 2 0 FAM92 protein Octopine_DH PF02317.17 ORY02479.1 - 0.13 12.3 0.2 0.45 10.6 0.2 1.9 1 1 0 1 1 1 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain Tom37 PF10568.9 ORY02480.1 - 1.8e-32 112.3 0.2 3e-32 111.6 0.2 1.4 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_6 PF17171.4 ORY02480.1 - 1.1e-14 53.9 0.0 2.1e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 ORY02480.1 - 1.8e-05 25.4 0.0 3.1e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_2 PF13410.6 ORY02480.1 - 0.04 13.9 0.1 0.11 12.6 0.1 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Spc7 PF08317.11 ORY02486.1 - 5.3e-112 373.7 8.5 6.5e-112 373.4 8.5 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein Spc7_C2 PF15577.6 ORY02486.1 - 5.5e-20 71.2 0.2 1.1e-19 70.2 0.2 1.5 1 0 0 1 1 1 1 Spc7_C2 FapA PF03961.13 ORY02486.1 - 0.016 13.8 0.7 0.024 13.2 0.7 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A FliJ PF02050.16 ORY02486.1 - 0.023 14.9 8.3 0.05 13.8 8.3 1.6 1 0 0 1 1 1 0 Flagellar FliJ protein DUF4407 PF14362.6 ORY02486.1 - 0.21 10.9 4.8 0.44 9.9 4.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Exonuc_VII_L PF02601.15 ORY02486.1 - 3.8 7.0 8.1 6 6.3 7.6 1.4 1 1 0 1 1 1 0 Exonuclease VII, large subunit Seryl_tRNA_N PF02403.22 ORY02486.1 - 9.3 6.5 10.9 10 6.4 8.8 2.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain M20_dimer PF07687.14 ORY02545.1 - 2.7e-13 49.8 0.0 4.8e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 ORY02545.1 - 3.7e-12 46.4 0.0 3.7e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Chitin_synth_2 PF03142.15 ORY02546.1 - 0.00042 19.1 0.1 0.00045 19.0 0.1 1.0 1 0 0 1 1 1 1 Chitin synthase Ceramidase PF05875.12 ORY02547.1 - 0.045 13.2 0.3 0.073 12.5 0.3 1.2 1 0 0 1 1 1 0 Ceramidase F-box PF00646.33 ORY02549.1 - 3.5e-05 23.6 0.1 0.00013 21.7 0.1 2.0 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 ORY02549.1 - 0.0015 18.4 0.1 0.0051 16.7 0.1 1.9 1 0 0 1 1 1 1 F-box-like MgtE_N PF03448.17 ORY02549.1 - 0.046 14.3 0.0 0.1 13.2 0.0 1.5 1 0 0 1 1 1 0 MgtE intracellular N domain PRANC PF09372.10 ORY02549.1 - 0.15 12.4 0.0 0.35 11.2 0.0 1.6 1 0 0 1 1 1 0 PRANC domain Arc PF03869.14 ORY02550.1 - 0.017 14.9 0.1 0.031 14.1 0.1 1.4 1 0 0 1 1 1 0 Arc-like DNA binding domain His_Phos_2 PF00328.22 ORY02552.1 - 1.5e-27 97.0 0.0 2.7e-27 96.1 0.0 1.4 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Fungal_trans_2 PF11951.8 ORY02553.1 - 1.2e-41 142.8 0.9 1.8e-41 142.2 0.9 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY02553.1 - 2.2e-08 34.1 11.4 4.3e-08 33.2 11.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TIG PF01833.24 ORY02554.1 - 0.035 14.2 0.5 0.28 11.3 0.0 2.1 2 0 0 2 2 2 0 IPT/TIG domain adh_short PF00106.25 ORY02555.1 - 8.5e-31 106.9 0.0 1.2e-30 106.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY02555.1 - 9.2e-25 87.6 0.0 1.9e-24 86.5 0.0 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY02555.1 - 1.8e-07 31.3 0.1 6.1e-06 26.3 0.0 2.1 2 0 0 2 2 2 1 KR domain Methyltransf_25 PF13649.6 ORY02555.1 - 0.029 15.1 0.0 0.052 14.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Eno-Rase_NADH_b PF12242.8 ORY02555.1 - 0.073 12.8 0.1 0.14 11.9 0.1 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase HI0933_like PF03486.14 ORY02555.1 - 0.11 11.2 0.2 0.13 10.9 0.2 1.1 1 0 0 1 1 1 0 HI0933-like protein DUF3176 PF11374.8 ORY02557.1 - 4e-29 101.0 1.1 4e-29 101.0 1.1 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3176) DUF4328 PF14219.6 ORY02557.1 - 0.0058 16.2 1.1 0.0058 16.2 1.1 1.9 1 1 1 2 2 2 1 Domain of unknown function (DUF4328) Cu_amine_oxid PF01179.20 ORY02558.1 - 2.7e-72 244.0 0.2 5.2e-52 177.1 0.0 3.1 2 1 0 2 2 2 2 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.16 ORY02558.1 - 0.039 14.2 0.0 0.098 12.9 0.0 1.7 1 0 0 1 1 1 0 Copper amine oxidase, N2 domain zf-C2H2 PF00096.26 ORY02559.1 - 1.3e-11 44.2 11.0 0.004 17.5 0.3 3.3 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY02559.1 - 8.8e-09 35.5 11.4 0.0068 17.2 0.6 3.2 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORY02559.1 - 3.7e-06 27.1 13.1 0.049 14.1 0.5 4.2 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_11 PF16622.5 ORY02559.1 - 6e-05 22.7 3.9 0.024 14.4 0.1 3.4 3 0 0 3 3 3 1 zinc-finger C2H2-type zf_UBZ PF18439.1 ORY02559.1 - 0.00082 18.9 0.9 0.39 10.3 0.1 2.6 2 0 0 2 2 2 2 Ubiquitin-Binding Zinc Finger zf-C2H2_3rep PF18868.1 ORY02559.1 - 0.0029 18.3 2.0 0.0029 18.3 2.0 2.2 2 1 1 3 3 3 1 Zinc finger C2H2-type, 3 repeats zf-C2H2_aberr PF17017.5 ORY02559.1 - 0.0032 17.6 1.5 0.0034 17.5 0.5 1.5 1 1 1 2 2 2 1 Aberrant zinc-finger C1_4 PF07975.12 ORY02559.1 - 0.007 16.6 3.1 0.007 16.6 3.1 2.9 1 1 2 3 3 3 1 TFIIH C1-like domain DZR PF12773.7 ORY02559.1 - 0.012 15.7 3.9 0.031 14.3 0.4 2.2 2 0 0 2 2 2 0 Double zinc ribbon XPA_N PF01286.18 ORY02559.1 - 0.013 15.6 0.6 5.6 7.1 0.1 2.4 2 0 0 2 2 2 0 XPA protein N-terminal zinc_ribbon_5 PF13719.6 ORY02559.1 - 0.04 13.7 1.1 10 6.0 0.0 2.6 3 0 0 3 3 3 0 zinc-ribbon domain IBR PF01485.21 ORY02559.1 - 0.047 13.9 7.4 0.29 11.4 0.4 2.6 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain PhnA_Zn_Ribbon PF08274.12 ORY02559.1 - 0.078 13.0 1.5 4.4 7.3 0.1 2.3 2 0 0 2 2 2 0 PhnA Zinc-Ribbon zinc_ribbon_4 PF13717.6 ORY02559.1 - 0.098 12.6 6.0 3.1 7.8 0.1 3.5 3 1 1 4 4 4 0 zinc-ribbon domain zinc-ribbons_6 PF07191.12 ORY02559.1 - 0.16 11.9 4.4 0.37 10.8 2.4 2.3 1 1 0 1 1 1 0 zinc-ribbons zf-C2H2_jaz PF12171.8 ORY02559.1 - 0.24 11.7 3.9 5.8 7.3 0.7 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Rubredoxin_2 PF18073.1 ORY02559.1 - 0.95 9.2 5.1 1 9.2 0.3 2.3 2 0 0 2 2 2 0 Rubredoxin metal binding domain Zn-ribbon_8 PF09723.10 ORY02559.1 - 1.4 9.1 7.6 6.1 7.0 4.9 2.5 1 1 1 2 2 2 0 Zinc ribbon domain PHD PF00628.29 ORY02559.1 - 2 8.3 8.4 0.6 10.0 3.2 2.6 2 2 2 4 4 4 0 PHD-finger Zn_ribbon_recom PF13408.6 ORY02559.1 - 2.8 8.5 11.9 7.7 7.1 11.9 2.0 1 1 0 1 1 1 0 Recombinase zinc beta ribbon domain OrfB_Zn_ribbon PF07282.11 ORY02559.1 - 6.6 6.7 10.9 2.7 8.0 5.4 2.7 1 1 1 2 2 2 0 Putative transposase DNA-binding domain zf-MYST PF17772.1 ORY02559.1 - 7.2 6.3 8.5 12 5.6 0.5 3.1 2 1 1 3 3 3 0 MYST family zinc finger domain Zn_Tnp_IS1595 PF12760.7 ORY02559.1 - 8.5 6.4 13.8 2.9 8.0 8.2 2.3 2 1 0 2 2 2 0 Transposase zinc-ribbon domain SKG6 PF08693.10 ORY02560.1 - 0.012 15.0 0.1 0.022 14.1 0.1 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain zf-C2H2 PF00096.26 ORY02560.1 - 0.062 13.8 13.5 0.16 12.5 1.0 4.5 5 0 0 5 5 5 0 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 ORY02560.1 - 0.14 12.2 4.9 3.2 7.9 0.2 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger Voltage_CLC PF00654.20 ORY02561.1 - 1.9e-87 293.8 21.8 1.9e-87 293.8 21.8 2.0 2 0 0 2 2 2 2 Voltage gated chloride channel Lipase_GDSL_2 PF13472.6 ORY02562.1 - 2.5e-23 83.4 0.0 4.4e-23 82.6 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 ORY02562.1 - 9.4e-18 64.9 0.0 1.1e-17 64.7 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase UCH PF00443.29 ORY02564.1 - 1.7e-65 221.1 0.0 4e-65 219.9 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 ORY02564.1 - 8.4e-11 42.0 0.0 0.00067 19.3 0.1 3.0 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 ORY02564.1 - 1.1e-08 35.5 0.1 4.3e-08 33.7 0.0 2.1 3 0 0 3 3 3 1 DUSP domain USP7_C2 PF14533.6 ORY02564.1 - 0.00051 19.8 0.0 0.00092 19.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-specific protease C-terminal CCDC106 PF15794.5 ORY02564.1 - 9.7 5.8 11.3 29 4.3 11.3 1.8 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Sulfate_transp PF00916.20 ORY02566.1 - 6.3e-22 77.8 14.2 1e-21 77.2 14.2 1.3 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 ORY02566.1 - 0.021 14.4 0.0 0.047 13.3 0.0 1.5 1 0 0 1 1 1 0 STAS domain p450 PF00067.22 ORY02568.1 - 4.5e-73 246.6 0.0 5.3e-73 246.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 2OG-FeII_Oxy PF03171.20 ORY02569.1 - 1.3e-15 57.7 0.0 2.4e-15 56.9 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 ORY02569.1 - 1.9e-12 48.0 0.0 3.4e-12 47.1 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal LPD11 PF18824.1 ORY02569.1 - 0.012 15.7 0.3 0.59 10.3 0.1 2.4 2 0 0 2 2 2 0 Large polyvalent protein-associated domain 11 MFS_1 PF07690.16 ORY02570.1 - 2.5e-16 59.6 36.5 5.2e-16 58.5 36.5 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Phage_holin_2_4 PF16082.5 ORY02570.1 - 0.0049 16.6 0.0 0.017 14.9 0.0 1.9 1 0 0 1 1 1 1 Bacteriophage holin family, superfamily II-like HET PF06985.11 ORY02571.1 - 0.0043 17.4 0.0 0.0061 16.9 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ASTN_2_hairpin PF18577.1 ORY02571.1 - 0.06 13.5 0.0 0.093 12.9 0.0 1.3 1 0 0 1 1 1 0 Astrotactin-2 C-terminal beta-hairpin domain Pkinase PF00069.25 ORY02572.1 - 4.9e-37 127.7 0.0 1.3e-36 126.4 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY02572.1 - 3.9e-21 75.5 0.0 9.8e-21 74.2 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase IMPa_N_2 PF18650.1 ORY02572.1 - 0.041 13.2 0.0 0.069 12.4 0.0 1.3 1 0 0 1 1 1 0 Immunomodulating metalloprotease N-terminal domain Pkinase_fungal PF17667.1 ORY02572.1 - 0.052 12.3 0.0 0.071 11.9 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Dimer_Tnp_hAT PF05699.14 ORY02573.1 - 0.0021 17.8 0.7 0.0023 17.7 0.7 1.3 1 1 0 1 1 1 1 hAT family C-terminal dimerisation region Peptidase_M17_N PF02789.17 ORY02574.1 - 0.17 11.8 0.0 0.25 11.2 0.0 1.2 1 0 0 1 1 1 0 Cytosol aminopeptidase family, N-terminal domain ADH_zinc_N PF00107.26 ORY02576.1 - 1.1e-11 44.8 0.0 2.2e-11 43.8 0.0 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ORY02576.1 - 6.7e-07 29.2 0.0 0.0001 22.1 0.0 2.4 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 ORY02576.1 - 0.092 13.8 0.0 0.19 12.8 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Epimerase PF01370.21 ORY02577.1 - 5.6e-11 42.4 0.1 1e-10 41.5 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 ORY02577.1 - 1.2e-07 31.8 0.0 4.7e-07 29.9 0.0 2.0 1 1 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 ORY02577.1 - 4.2e-05 22.7 0.1 7.2e-05 21.9 0.1 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 ORY02577.1 - 5.8e-05 22.8 0.1 0.00012 21.7 0.1 1.5 1 0 0 1 1 1 1 NmrA-like family GDP_Man_Dehyd PF16363.5 ORY02577.1 - 0.00055 19.4 0.2 0.00088 18.8 0.1 1.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 ORY02577.1 - 0.003 17.0 0.2 0.02 14.4 0.1 2.2 2 1 0 2 2 2 1 short chain dehydrogenase Polysacc_synt_2 PF02719.15 ORY02577.1 - 0.0044 16.2 0.0 0.0064 15.7 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein FAD_binding_3 PF01494.19 ORY02578.1 - 4e-05 23.0 1.0 0.014 14.7 0.0 2.7 3 0 0 3 3 3 2 FAD binding domain DAO PF01266.24 ORY02578.1 - 0.00022 20.9 0.8 0.1 12.2 0.0 2.3 2 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 ORY02578.1 - 0.0012 19.4 0.1 0.56 10.8 0.0 2.8 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DUF4621 PF15414.6 ORY02578.1 - 0.11 11.4 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4621) NAD_binding_8 PF13450.6 ORY02578.1 - 0.17 12.1 0.0 0.17 12.1 0.0 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain dCMP_cyt_deam_1 PF00383.23 ORY02579.1 - 1.1e-08 34.8 0.0 1.8e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 ORY02579.1 - 8.7e-06 25.5 0.0 1.7e-05 24.6 0.0 1.6 1 1 0 1 1 1 1 MafB19-like deaminase SET PF00856.28 ORY02653.1 - 1.7e-10 41.5 0.5 3.6e-10 40.5 0.2 1.6 2 0 0 2 2 2 1 SET domain T2SSG PF08334.11 ORY02653.1 - 0.088 12.9 0.1 0.18 11.9 0.1 1.6 1 1 0 1 1 1 0 Type II secretion system (T2SS), protein G Cu-oxidase_3 PF07732.15 ORY02655.1 - 1.9e-43 147.2 2.2 5.3e-40 136.1 0.3 4.0 4 1 0 4 4 4 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 ORY02655.1 - 7.2e-40 135.9 7.1 9.8e-37 125.7 1.2 3.5 3 1 0 3 3 3 3 Multicopper oxidase Cu-oxidase PF00394.22 ORY02655.1 - 1.3e-28 100.2 0.9 5.4e-27 94.9 0.1 3.0 3 0 0 3 3 3 1 Multicopper oxidase AAA_12 PF13087.6 ORY02657.1 - 9.8e-40 136.3 0.0 1.7e-39 135.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 ORY02657.1 - 4.2e-24 85.8 0.0 7.9e-24 84.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 ORY02657.1 - 1.3e-08 35.3 0.0 1.1e-07 32.2 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 ORY02657.1 - 3.8e-05 23.5 0.0 0.0092 15.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain DUF2075 PF09848.9 ORY02657.1 - 4.4e-05 22.9 0.1 0.34 10.1 0.0 2.9 2 1 1 3 3 3 2 Uncharacterized conserved protein (DUF2075) UvrD-helicase PF00580.21 ORY02657.1 - 0.049 13.1 0.2 0.25 10.8 0.0 2.2 2 1 0 2 2 2 0 UvrD/REP helicase N-terminal domain zf_CCCH_4 PF18345.1 ORY02657.1 - 0.14 12.3 6.7 0.43 10.7 6.7 2.0 1 0 0 1 1 1 0 Zinc finger domain F-actin_cap_A PF01267.17 ORY02658.1 - 1.8e-96 322.7 0.0 2e-96 322.5 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit CdiI_2 PF18593.1 ORY02658.1 - 0.09 13.4 0.1 0.29 11.8 0.0 1.8 2 0 0 2 2 2 0 CdiI immunity protein VHS PF00790.19 ORY02661.1 - 3.6e-26 91.7 0.1 8.8e-26 90.4 0.0 1.6 2 0 0 2 2 2 1 VHS domain GAT PF03127.14 ORY02661.1 - 0.00016 21.9 0.6 0.00039 20.7 0.6 1.7 1 0 0 1 1 1 1 GAT domain PGAP1 PF07819.13 ORY02662.1 - 0.13 12.0 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein DUF5518 PF17647.1 ORY02662.1 - 0.3 11.2 8.6 0.45 10.7 8.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5518) Sugar_tr PF00083.24 ORY02663.1 - 3.2e-81 273.5 24.4 3.9e-81 273.2 24.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY02663.1 - 4.9e-21 75.0 60.4 1.2e-18 67.2 29.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 ORY02663.1 - 1.6e-05 24.4 9.9 1.6e-05 24.4 9.9 2.3 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Phage_holin_5_1 PF06946.11 ORY02663.1 - 9 6.8 8.3 21 5.6 0.5 3.1 2 1 1 3 3 3 0 Bacteriophage A118-like holin, Hol118 Fungal_trans_2 PF11951.8 ORY02664.1 - 1.1e-10 40.9 3.1 1.1e-07 31.0 0.7 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain DUF89 PF01937.19 ORY02665.1 - 1.4e-104 349.9 0.1 1.6e-104 349.7 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 AnmK PF03702.14 ORY02666.1 - 2.1e-78 264.0 0.0 2.7e-78 263.7 0.0 1.0 1 0 0 1 1 1 1 Anhydro-N-acetylmuramic acid kinase FGGY_C PF02782.16 ORY02666.1 - 0.019 14.7 0.0 0.036 13.8 0.0 1.4 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain A_thal_3526 PF09713.10 ORY02666.1 - 0.043 14.1 0.0 0.086 13.1 0.0 1.5 1 0 0 1 1 1 0 Plant protein 1589 of unknown function (A_thal_3526) PRIMA1 PF16101.5 ORY02667.1 - 0.22 11.6 4.1 0.45 10.6 4.1 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Cytomega_UL20A PF05984.12 ORY02668.1 - 0.37 11.1 1.1 11 6.3 0.1 2.6 2 0 0 2 2 2 0 Cytomegalovirus UL20A protein Methyltransf_23 PF13489.6 ORY02669.1 - 1.9e-24 86.3 0.0 4e-24 85.3 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY02669.1 - 4.2e-09 36.4 0.0 4.9e-08 32.9 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY02669.1 - 5.3e-09 36.7 0.0 1.8e-08 35.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY02669.1 - 1.6e-06 28.7 0.0 3.5e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY02669.1 - 1.6e-05 25.5 0.0 0.00013 22.6 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORY02669.1 - 0.00059 19.3 0.0 0.012 15.0 0.0 2.6 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family KH_1 PF00013.29 ORY02671.1 - 8.7e-100 326.6 35.7 9.8e-14 50.9 0.2 14.0 14 1 0 14 14 14 11 KH domain SLS PF14611.6 ORY02671.1 - 7e-16 58.7 0.8 0.08 12.8 0.1 7.7 4 2 4 8 8 8 5 Mitochondrial inner-membrane-bound regulator KH_2 PF07650.17 ORY02671.1 - 9.2e-11 41.4 22.9 0.12 12.2 0.2 8.7 7 1 0 8 8 8 5 KH domain ZU5 PF00791.20 ORY02671.1 - 0.12 12.7 0.1 6.7 7.1 0.0 3.7 3 1 0 3 3 3 0 ZU5 domain KH_5 PF13184.6 ORY02671.1 - 0.51 10.5 9.9 57 3.9 0.1 5.3 5 0 0 5 5 5 0 NusA-like KH domain BMC PF00936.19 ORY02671.1 - 1.8 8.6 3.8 22 5.1 0.0 4.0 5 0 0 5 5 5 0 BMC domain Nrf1_activ_bdg PF10492.9 ORY02671.1 - 8.8 7.1 6.8 35 5.2 0.1 4.1 4 0 0 4 4 4 0 Nrf1 activator activation site binding domain 12TM_1 PF09847.9 ORY02673.1 - 0.2 10.7 0.2 0.34 10.0 0.2 1.3 1 0 0 1 1 1 0 Membrane protein of 12 TMs VHS PF00790.19 ORY02674.1 - 2e-35 121.7 1.0 3.3e-35 121.0 1.0 1.4 1 0 0 1 1 1 1 VHS domain SH3_1 PF00018.28 ORY02674.1 - 2e-16 59.3 0.0 4.2e-16 58.3 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 ORY02674.1 - 1.4e-14 53.7 0.0 2.6e-14 52.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 ORY02674.1 - 2.4e-14 52.8 0.0 4.4e-14 51.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain GAT PF03127.14 ORY02674.1 - 1.7e-11 44.3 0.9 3.8e-11 43.1 0.1 1.9 2 0 0 2 2 2 1 GAT domain UIM PF02809.20 ORY02674.1 - 0.0045 16.8 3.8 0.011 15.6 3.8 1.7 1 0 0 1 1 1 1 Ubiquitin interaction motif Pkinase PF00069.25 ORY02675.1 - 1.4e-71 241.0 0.0 1.8e-71 240.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY02675.1 - 3.1e-44 151.2 0.0 4.6e-44 150.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 ORY02675.1 - 1.8e-22 79.4 0.2 4e-22 78.3 0.2 1.6 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.6 ORY02675.1 - 4.7e-07 29.4 0.0 8.5e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 ORY02675.1 - 1.7e-06 27.1 0.0 3.3e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 ORY02675.1 - 0.016 14.2 1.0 0.084 11.8 1.0 2.0 1 1 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 ORY02675.1 - 0.034 13.5 0.4 0.2 11.0 0.0 2.1 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DSHCT PF08148.12 ORY02675.1 - 0.054 13.2 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 DSHCT (NUC185) domain APH PF01636.23 ORY02675.1 - 0.11 12.4 0.1 0.73 9.7 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family PHY PF00360.20 ORY02677.1 - 9.5e-29 100.0 0.0 2.5e-28 98.6 0.0 1.7 1 0 0 1 1 1 1 Phytochrome region HATPase_c PF02518.26 ORY02677.1 - 1.6e-19 70.5 0.1 3.3e-19 69.4 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 ORY02677.1 - 8.5e-15 54.9 0.0 2.9e-14 53.2 0.0 2.0 1 0 0 1 1 1 1 Response regulator receiver domain GAF PF01590.26 ORY02677.1 - 1.5e-12 48.3 0.0 1.3e-11 45.3 0.0 2.3 2 0 0 2 2 2 1 GAF domain HisKA PF00512.25 ORY02677.1 - 2.1e-12 46.9 2.7 2.6e-12 46.6 1.1 2.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_2 PF08446.11 ORY02677.1 - 2.2e-07 31.5 0.0 5.3e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 PAS fold HATPase_c_3 PF13589.6 ORY02677.1 - 0.0096 15.8 1.2 0.18 11.7 0.1 2.3 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 ORY02677.1 - 0.013 15.5 0.1 0.035 14.1 0.1 1.7 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain HATPase_c_5 PF14501.6 ORY02677.1 - 0.044 13.7 0.0 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 GHKL domain Flavoprotein PF02441.19 ORY02678.1 - 7e-13 48.6 0.0 1.2e-12 47.8 0.0 1.5 1 0 0 1 1 1 1 Flavoprotein GH-E PF14410.6 ORY02678.1 - 0.098 13.1 1.6 6.5 7.2 0.2 2.7 2 0 0 2 2 2 0 HNH/ENDO VII superfamily nuclease with conserved GHE residues Dimer_Tnp_hAT PF05699.14 ORY02678.1 - 0.81 9.5 7.0 16 5.4 0.1 4.7 5 1 1 6 6 6 0 hAT family C-terminal dimerisation region Cyt-b5 PF00173.28 ORY02679.1 - 2e-21 75.9 0.2 2.7e-21 75.5 0.2 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain U62_UL91 PF17442.2 ORY02679.1 - 0.019 15.0 0.0 0.034 14.1 0.0 1.3 1 0 0 1 1 1 0 Functional domain of U62 and UL91 proteins Abhydrolase_2 PF02230.16 ORY02680.1 - 6.7e-22 78.4 0.0 1.3e-10 41.4 0.0 3.1 3 0 0 3 3 3 3 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 ORY02680.1 - 1.2e-05 24.9 0.0 0.00025 20.6 0.0 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 ORY02680.1 - 2.9e-05 24.8 0.0 4.4e-05 24.2 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 ORY02680.1 - 0.026 14.1 0.0 0.056 13.1 0.0 1.7 1 1 0 1 1 1 0 Putative esterase Hydrolase_4 PF12146.8 ORY02680.1 - 0.055 12.7 0.0 0.41 9.9 0.0 2.1 2 0 0 2 2 2 0 Serine aminopeptidase, S33 APH PF01636.23 ORY02681.1 - 4.2e-12 46.5 0.0 1.1e-11 45.1 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 ORY02681.1 - 0.0021 17.7 0.0 0.0031 17.1 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 ORY02681.1 - 0.0067 16.0 0.0 0.16 11.6 0.0 2.1 2 0 0 2 2 2 1 RIO1 family DUF3770 PF12603.8 ORY02681.1 - 0.11 12.0 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3770) NUC153 PF08159.12 ORY02682.1 - 1.6e-11 43.8 1.8 4e-11 42.5 1.8 1.7 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.32 ORY02682.1 - 0.00015 22.5 0.6 7.1 7.7 0.0 4.3 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY02682.1 - 0.063 13.6 0.0 0.28 11.5 0.0 2.1 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain Med13_C PF06333.12 ORY02683.1 - 1.4e-70 238.2 0.6 1.4e-70 238.2 0.6 2.7 4 0 0 4 4 4 1 Mediator complex subunit 13 C-terminal domain Med13_N PF11597.8 ORY02683.1 - 8.3e-51 173.2 0.8 1.9e-50 172.0 0.8 1.7 1 0 0 1 1 1 1 Mediator complex subunit 13 N-terminal MID_MedPIWI PF18296.1 ORY02683.1 - 7.7e-31 107.8 0.5 1.1e-28 100.7 0.0 3.4 2 1 0 2 2 2 1 MID domain of medPIWI YMF19 PF02326.15 ORY02684.1 - 0.0079 16.9 0.2 0.021 15.6 0.2 1.8 1 1 0 1 1 1 1 Plant ATP synthase F0 Presenilin PF01080.17 ORY02684.1 - 0.89 8.2 4.4 1.2 7.8 4.4 1.2 1 0 0 1 1 1 0 Presenilin DHHC PF01529.20 ORY02685.1 - 2.6e-34 118.2 2.1 2.6e-34 118.2 2.1 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase IGFBP PF00219.18 ORY02685.1 - 2.2 9.0 6.2 3.6 8.3 6.2 1.2 1 0 0 1 1 1 0 Insulin-like growth factor binding protein Myb_DNA-bind_2 PF08914.11 ORY02686.1 - 1.2e-19 70.2 0.4 3e-19 68.9 0.4 1.7 1 0 0 1 1 1 1 Rap1 Myb domain Rap1_C PF11626.8 ORY02686.1 - 1e-15 57.5 0.1 2.9e-15 56.1 0.1 1.8 1 0 0 1 1 1 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain BRCT_2 PF16589.5 ORY02686.1 - 3.6e-09 36.9 0.0 7.7e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain HMG_box PF00505.19 ORY02686.1 - 3e-07 30.8 1.2 1.3e-06 28.7 1.2 2.1 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 ORY02686.1 - 0.0017 18.9 1.1 0.0053 17.3 1.1 1.9 1 0 0 1 1 1 1 HMG-box domain Rap1-DNA-bind PF09197.10 ORY02686.1 - 0.003 18.1 0.1 0.003 18.1 0.1 2.9 3 1 0 3 3 3 1 Rap1, DNA-binding F-box-like_2 PF13013.6 ORY02687.1 - 0.013 15.5 0.2 0.037 14.0 0.2 1.8 1 1 0 1 1 1 0 F-box-like domain Phage_fiber_C PF06820.12 ORY02687.1 - 0.049 14.0 0.3 0.14 12.5 0.1 1.9 2 0 0 2 2 2 0 Putative prophage tail fibre C-terminus TPR_2 PF07719.17 ORY02687.1 - 0.94 9.8 6.3 4.3 7.7 0.8 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat AA_permease PF00324.21 ORY02730.1 - 4.8e-114 381.6 39.9 5.9e-114 381.3 39.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ORY02730.1 - 7.2e-33 114.0 46.7 9e-33 113.7 46.7 1.0 1 0 0 1 1 1 1 Amino acid permease Herpes_US9 PF06072.11 ORY02731.1 - 0.19 11.6 0.0 0.31 10.9 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 MFS_1 PF07690.16 ORY02732.1 - 9.1e-16 57.7 32.3 9.1e-16 57.7 32.3 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.18 ORY02734.1 - 1.6e-16 60.1 0.1 2.6e-16 59.4 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain FliS PF02561.14 ORY02734.1 - 0.038 14.3 0.0 0.095 13.0 0.0 1.6 1 0 0 1 1 1 0 Flagellar protein FliS F-box PF00646.33 ORY02735.1 - 0.0012 18.7 0.1 0.0041 16.9 0.1 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 ORY02735.1 - 0.021 14.7 1.4 0.036 14.0 0.3 1.9 2 0 0 2 2 2 0 F-box-like DUF1768 PF08719.11 ORY02736.1 - 2.1e-53 180.8 0.2 2.7e-53 180.5 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Enkurin PF13864.6 ORY02737.1 - 0.014 15.8 0.5 0.034 14.6 0.5 1.6 1 0 0 1 1 1 0 Calmodulin-binding DegS PF05384.11 ORY02737.1 - 0.017 14.7 1.3 0.029 13.9 1.3 1.3 1 0 0 1 1 1 0 Sensor protein DegS DUF4140 PF13600.6 ORY02737.1 - 0.07 13.6 1.6 0.26 11.8 0.9 2.3 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) PEARLI-4 PF05278.12 ORY02737.1 - 0.18 11.4 0.4 0.29 10.7 0.4 1.2 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) bZIP_2 PF07716.15 ORY02737.1 - 0.36 10.9 6.2 0.95 9.6 6.2 1.7 1 0 0 1 1 1 0 Basic region leucine zipper DivIC PF04977.15 ORY02737.1 - 0.43 10.4 1.8 1.1 9.1 1.8 1.6 1 0 0 1 1 1 0 Septum formation initiator Oxidored-like PF09791.9 ORY02738.1 - 1e-25 89.1 3.8 2.3e-25 88.0 3.8 1.6 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal DPM3 PF08285.11 ORY02739.1 - 2.2e-36 123.9 0.1 2.4e-36 123.8 0.1 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DUF2523 PF10734.9 ORY02739.1 - 0.077 13.6 0.1 0.14 12.7 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2523) Arm PF00514.23 ORY02740.1 - 0.0035 17.3 1.0 0.043 13.9 0.2 3.5 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.20 ORY02742.1 - 6.9e-123 411.0 4.6 9e-123 410.6 4.6 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.16 ORY02742.1 - 2.6e-48 162.9 0.0 5.9e-48 161.7 0.0 1.6 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.20 ORY02742.1 - 2e-16 60.2 0.0 4e-16 59.3 0.0 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 ORY02742.1 - 6.6e-05 23.0 0.1 0.026 14.5 0.0 2.7 1 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 ORY02742.1 - 0.07 13.5 0.7 2.5 8.6 0.1 3.5 3 1 0 3 3 3 0 HEAT repeats HET PF06985.11 ORY02743.1 - 1.9e-27 96.4 0.0 2.8e-27 95.9 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ketoacyl-synt PF00109.26 ORY02745.1 - 2.5e-74 250.0 0.0 5.1e-74 249.0 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 ORY02745.1 - 5.3e-51 173.1 1.2 2.3e-49 167.8 0.1 3.1 3 0 0 3 3 3 1 KR domain PS-DH PF14765.6 ORY02745.1 - 6e-48 163.6 0.9 2.7e-47 161.4 0.3 2.2 2 0 0 2 2 2 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 ORY02745.1 - 1.4e-43 149.7 0.1 2.5e-43 148.8 0.1 1.3 1 0 0 1 1 1 1 Acyl transferase domain NAD_binding_4 PF07993.12 ORY02745.1 - 8.5e-31 107.0 0.0 1.8e-30 106.0 0.0 1.6 1 0 0 1 1 1 1 Male sterility protein Ketoacyl-synt_C PF02801.22 ORY02745.1 - 7.4e-28 96.9 0.0 1.9e-27 95.6 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 ORY02745.1 - 1.6e-20 73.7 0.0 3.3e-19 69.5 0.0 3.1 4 0 0 4 4 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY02745.1 - 2.4e-15 57.0 0.0 2.7e-14 53.6 0.0 3.0 3 0 0 3 3 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY02745.1 - 2.7e-15 56.6 0.0 6.1e-15 55.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.21 ORY02745.1 - 1.9e-14 53.7 0.0 5.7e-11 42.3 0.0 2.8 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family Methyltransf_11 PF08241.12 ORY02745.1 - 1.4e-13 51.2 0.0 4.9e-13 49.6 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 ORY02745.1 - 1.5e-13 51.1 0.0 5e-13 49.5 0.0 1.9 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 ORY02745.1 - 1.3e-12 47.6 0.0 1e-11 44.7 0.1 2.5 3 0 0 3 3 3 1 short chain dehydrogenase Methyltransf_31 PF13847.6 ORY02745.1 - 2.1e-10 40.6 0.0 4.8e-10 39.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORY02745.1 - 1.5e-08 34.3 0.0 3.6e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family 3Beta_HSD PF01073.19 ORY02745.1 - 9.1e-07 28.2 0.0 4.6e-05 22.6 0.0 2.5 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Thiolase_N PF00108.23 ORY02745.1 - 6e-06 25.8 0.1 1.5e-05 24.5 0.1 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain adh_short_C2 PF13561.6 ORY02745.1 - 8.2e-05 22.3 0.1 0.00019 21.0 0.1 1.6 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase GDP_Man_Dehyd PF16363.5 ORY02745.1 - 0.01 15.3 0.0 5 6.4 0.0 3.0 3 0 0 3 3 3 0 GDP-mannose 4,6 dehydratase PP-binding PF00550.25 ORY02745.1 - 0.017 15.5 0.1 0.059 13.7 0.1 2.0 1 1 0 1 1 1 0 Phosphopantetheine attachment site Methyltransf_33 PF10017.9 ORY02745.1 - 0.098 11.8 0.0 0.4 9.8 0.0 2.0 2 0 0 2 2 2 0 Histidine-specific methyltransferase, SAM-dependent NNMT_PNMT_TEMT PF01234.17 ORY02745.1 - 0.15 11.2 0.0 1.4 8.0 0.0 2.4 3 0 0 3 3 3 0 NNMT/PNMT/TEMT family PCMT PF01135.19 ORY02745.1 - 0.16 11.7 0.0 0.36 10.5 0.0 1.5 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MFS_1 PF07690.16 ORY02746.1 - 1.1e-43 149.5 47.7 1.1e-43 149.5 47.7 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 ORY02746.1 - 4.3e-11 42.0 18.9 2.2e-10 39.6 18.9 2.0 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2830 PF11125.8 ORY02746.1 - 0.3 11.1 4.0 0.67 10.0 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2830) ADH_zinc_N PF00107.26 ORY02747.1 - 8.8e-09 35.4 0.2 1.8e-08 34.4 0.2 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ORY02747.1 - 0.00031 20.6 0.1 0.0028 17.5 0.2 2.4 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 ORY02747.1 - 0.015 16.3 0.0 0.026 15.6 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase adh_short PF00106.25 ORY02748.1 - 1.8e-22 79.7 0.0 1.5e-21 76.7 0.1 1.9 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY02748.1 - 2.2e-14 53.6 0.0 2e-13 50.4 0.0 1.9 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY02748.1 - 6.3e-09 36.0 0.0 8.6e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ORY02748.1 - 0.00052 19.5 0.0 0.00097 18.7 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family TIR-like PF10137.9 ORY02748.1 - 0.014 15.3 0.0 0.021 14.8 0.0 1.2 1 0 0 1 1 1 0 Predicted nucleotide-binding protein containing TIR-like domain THF_DHG_CYH_C PF02882.19 ORY02748.1 - 0.024 13.9 0.0 0.04 13.2 0.0 1.2 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GDP_Man_Dehyd PF16363.5 ORY02748.1 - 0.032 13.6 0.0 0.049 13.0 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Shikimate_DH PF01488.20 ORY02748.1 - 0.076 13.1 0.1 0.11 12.5 0.1 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase p450 PF00067.22 ORY02749.1 - 1.7e-63 215.0 0.0 2.3e-63 214.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 AATase PF07247.12 ORY02750.1 - 7.7e-12 44.5 0.0 2.1e-11 43.1 0.0 1.6 1 1 0 1 1 1 1 Alcohol acetyltransferase ketoacyl-synt PF00109.26 ORY02751.1 - 4.4e-71 239.4 0.1 1.7e-70 237.5 0.0 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 ORY02751.1 - 2.2e-57 193.9 0.2 5.2e-57 192.6 0.2 1.7 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 ORY02751.1 - 2.8e-53 181.1 0.0 4.7e-53 180.3 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 ORY02751.1 - 1.9e-41 142.6 0.1 3.4e-41 141.8 0.1 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 ORY02751.1 - 3.9e-41 139.8 0.1 8.9e-41 138.6 0.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N_2 PF13602.6 ORY02751.1 - 2.1e-20 74.1 0.0 8.5e-17 62.5 0.0 3.6 3 0 0 3 3 3 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.12 ORY02751.1 - 8.1e-19 68.2 0.0 4.7e-18 65.8 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain ADH_zinc_N PF00107.26 ORY02751.1 - 2.1e-15 56.8 0.1 1.7e-14 53.9 0.0 2.5 3 0 0 3 3 2 1 Zinc-binding dehydrogenase KAsynt_C_assoc PF16197.5 ORY02751.1 - 3.8e-14 53.1 0.0 2.7e-12 47.1 0.0 2.6 1 1 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_23 PF13489.6 ORY02751.1 - 3e-12 46.7 0.0 8.7e-12 45.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY02751.1 - 1e-10 42.2 0.1 1.1e-09 38.8 0.0 3.0 3 0 0 3 3 1 1 Methyltransferase domain adh_short PF00106.25 ORY02751.1 - 1.1e-09 38.0 1.7 1.2e-09 37.9 0.2 1.9 2 0 0 2 2 2 1 short chain dehydrogenase Methyltransf_11 PF08241.12 ORY02751.1 - 1e-08 35.7 0.1 8.3e-08 32.8 0.0 2.7 3 0 0 3 3 2 1 Methyltransferase domain PP-binding PF00550.25 ORY02751.1 - 2.2e-07 31.1 0.1 9.8e-07 29.0 0.1 2.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site Ubie_methyltran PF01209.18 ORY02751.1 - 8.8e-07 28.5 0.0 2.1e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 ORY02751.1 - 2e-06 27.7 0.0 5.5e-06 26.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.23 ORY02751.1 - 0.00021 20.8 0.2 0.00049 19.5 0.2 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain Sacchrp_dh_NADP PF03435.18 ORY02751.1 - 0.0029 17.8 0.1 0.014 15.6 0.1 2.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain F420_oxidored PF03807.17 ORY02751.1 - 0.023 15.3 1.0 0.093 13.3 0.1 2.6 2 0 0 2 2 1 0 NADP oxidoreductase coenzyme F420-dependent ACP_syn_III PF08545.10 ORY02751.1 - 0.028 14.3 0.2 0.086 12.7 0.2 1.9 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III TrkA_N PF02254.18 ORY02751.1 - 0.031 14.5 0.1 0.14 12.5 0.1 2.1 1 0 0 1 1 1 0 TrkA-N domain Methyltransf_16 PF10294.9 ORY02751.1 - 0.042 13.6 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 Lysine methyltransferase Polysacc_synt_2 PF02719.15 ORY02751.1 - 0.062 12.4 0.0 0.094 11.8 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Methyltransf_2 PF00891.18 ORY02751.1 - 0.066 12.5 0.0 1.5 8.0 0.0 2.7 2 1 1 3 3 3 0 O-methyltransferase domain Methyltransf_8 PF05148.15 ORY02751.1 - 0.079 12.8 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Hypothetical methyltransferase 3Beta_HSD PF01073.19 ORY02751.1 - 0.081 11.9 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 ORY02751.1 - 0.091 12.6 0.2 0.28 11.0 0.2 1.9 1 0 0 1 1 1 0 NAD(P)H-binding p450 PF00067.22 ORY02752.1 - 4.6e-68 230.1 0.0 6e-68 229.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 ORY02753.1 - 9.3e-39 133.3 51.7 1.9e-37 129.0 26.5 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily PsbH PF00737.20 ORY02753.1 - 7.2 6.4 7.2 7.8 6.3 0.1 2.9 2 0 0 2 2 2 0 Photosystem II 10 kDa phosphoprotein FAD_binding_4 PF01565.23 ORY02754.1 - 1.5e-14 54.0 3.3 2.5e-14 53.2 3.3 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 ORY02754.1 - 1e-10 41.5 0.4 6.4e-10 39.0 0.0 2.3 2 0 0 2 2 2 1 Berberine and berberine like Cytokin-bind PF09265.10 ORY02754.1 - 0.13 11.6 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding p450 PF00067.22 ORY02755.1 - 8.8e-33 113.7 0.3 5.3e-32 111.2 0.3 2.0 1 1 0 1 1 1 1 Cytochrome P450 FAD_binding_4 PF01565.23 ORY02756.1 - 1.1e-27 96.5 0.5 1.7e-27 95.8 0.5 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 ORY02756.1 - 0.00018 21.6 0.0 0.00035 20.6 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like Zn_clus PF00172.18 ORY02759.1 - 4.7e-06 26.6 5.1 7.6e-06 26.0 5.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ras PF00071.22 ORY02829.1 - 5.1e-16 58.7 0.0 8.2e-16 58.0 0.0 1.3 1 1 0 1 1 1 1 Ras family Roc PF08477.13 ORY02829.1 - 0.00049 20.3 0.0 0.0018 18.5 0.0 1.9 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase DUF4360 PF14273.6 ORY02831.1 - 5.4e-09 36.2 0.1 7e-09 35.8 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) MFS_1 PF07690.16 ORY02832.1 - 2.3e-28 99.1 24.6 3.8e-28 98.4 24.6 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF3894 PF13033.6 ORY02832.1 - 1.7 8.8 6.6 1.5 9.0 0.1 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF3894) Dor1 PF04124.12 ORY02833.1 - 4.7e-52 176.7 2.5 2.3e-40 138.4 5.3 2.2 2 0 0 2 2 2 2 Dor1-like family DUF4208 PF13907.6 ORY02833.1 - 0.0026 18.1 0.1 0.0073 16.7 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4208) IFT46_B_C PF12317.8 ORY02833.1 - 0.0028 17.4 0.5 0.0061 16.3 0.1 1.7 2 0 0 2 2 2 1 Intraflagellar transport complex B protein 46 C terminal SLX9 PF15341.6 ORY02833.1 - 0.18 12.2 2.0 0.51 10.7 2.0 1.9 1 1 0 1 1 1 0 Ribosome biogenesis protein SLX9 UQ_con PF00179.26 ORY02834.1 - 1.8e-21 76.3 0.0 3.1e-21 75.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 ORY02834.1 - 0.0028 17.5 0.0 0.0059 16.5 0.0 1.6 1 0 0 1 1 1 1 UEV domain TPR_12 PF13424.6 ORY02835.1 - 3.1e-170 552.9 71.1 5.2e-20 71.5 0.4 11.2 1 1 11 12 12 12 12 Tetratricopeptide repeat TPR_10 PF13374.6 ORY02835.1 - 1.6e-137 444.2 24.1 2e-12 46.5 0.0 12.8 13 0 0 13 13 12 12 Tetratricopeptide repeat TPR_7 PF13176.6 ORY02835.1 - 1.5e-34 115.4 24.4 0.00082 19.2 0.0 12.6 12 0 0 12 12 12 9 Tetratricopeptide repeat TPR_8 PF13181.6 ORY02835.1 - 6.2e-32 107.1 20.2 0.05 13.8 0.0 12.3 12 0 0 12 12 12 8 Tetratricopeptide repeat TPR_1 PF00515.28 ORY02835.1 - 1.6e-29 100.5 24.7 0.0035 17.1 0.1 12.5 12 0 0 12 12 12 9 Tetratricopeptide repeat TPR_2 PF07719.17 ORY02835.1 - 3.4e-27 92.3 34.4 0.011 15.7 0.5 12.5 12 0 0 12 12 12 9 Tetratricopeptide repeat TPR_14 PF13428.6 ORY02835.1 - 9.1e-26 88.3 31.2 0.12 13.3 0.0 12.6 9 3 3 12 12 12 6 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY02835.1 - 2.2e-21 75.8 0.0 0.0071 16.6 0.2 9.6 1 1 9 10 10 10 6 Anaphase-promoting complex, cyclosome, subunit 3 TPR_MalT PF17874.1 ORY02835.1 - 1.1e-20 74.4 27.2 5.2e-08 32.6 3.2 6.0 2 1 5 7 7 7 5 MalT-like TPR region TPR_16 PF13432.6 ORY02835.1 - 2e-19 69.9 36.1 5.7e-05 23.7 0.3 10.1 6 3 3 9 9 8 7 Tetratricopeptide repeat TPR_4 PF07721.14 ORY02835.1 - 1e-18 66.0 15.4 0.73 10.6 0.2 12.3 12 0 0 12 12 12 2 Tetratricopeptide repeat Clr5 PF14420.6 ORY02835.1 - 3.6e-14 52.7 2.2 8.4e-14 51.5 0.2 2.6 2 0 0 2 2 2 1 Clr5 domain TPR_19 PF14559.6 ORY02835.1 - 1.1e-08 35.5 21.0 0.45 11.1 0.0 8.2 3 2 7 10 10 10 4 Tetratricopeptide repeat TPR_17 PF13431.6 ORY02835.1 - 1.4e-08 34.5 6.0 1.6e+02 3.0 0.0 10.8 12 0 0 12 12 12 0 Tetratricopeptide repeat NRBF2_MIT PF17169.4 ORY02835.1 - 1.3e-06 28.5 8.6 7.8 6.8 0.0 9.2 8 2 0 9 9 9 0 MIT domain of nuclear receptor-binding factor 2 TPR_9 PF13371.6 ORY02835.1 - 8.8e-06 25.8 7.1 5.6 7.2 0.3 6.8 4 1 1 6 6 6 1 Tetratricopeptide repeat DUF1925 PF09094.11 ORY02835.1 - 0.00013 22.2 1.9 76 3.7 0.0 8.0 10 0 0 10 10 10 0 Domain of unknown function (DUF1925) Atu4866 PF11512.8 ORY02835.1 - 0.002 18.5 20.3 42 4.6 0.0 9.2 8 2 2 10 10 10 0 Agrobacterium tumefaciens protein Atu4866 TetR_C_34 PF17929.1 ORY02835.1 - 0.0082 16.2 0.1 55 3.9 0.0 5.0 6 0 0 6 6 5 0 Tetracyclin repressor-like, C-terminal domain FPP PF05911.11 ORY02835.1 - 0.019 13.2 9.8 0.032 12.5 9.8 1.2 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil TPR_11 PF13414.6 ORY02835.1 - 0.2 11.4 25.7 16 5.3 0.0 9.6 11 0 0 11 11 11 0 TPR repeat FliD_N PF02465.18 ORY02835.1 - 2 9.1 4.7 99 3.7 4.1 2.6 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Exonuc_VII_L PF02601.15 ORY02835.1 - 3 7.3 6.5 9.1 5.7 6.5 1.8 1 0 0 1 1 1 0 Exonuclease VII, large subunit Phage_lysis PF03245.13 ORY02835.1 - 3.7 7.7 10.5 17 5.6 10.5 2.0 1 1 0 1 1 1 0 Bacteriophage Rz lysis protein AAA_23 PF13476.6 ORY02835.1 - 4.2 7.8 6.2 10 6.6 6.2 1.7 1 0 0 1 1 1 0 AAA domain GDPD PF03009.17 ORY02836.1 - 5.7e-12 45.9 0.0 1.7e-11 44.4 0.0 1.8 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Glyco_hydro_11 PF00457.17 ORY02837.1 - 2.8e-77 258.4 25.1 3.4e-77 258.1 25.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 DUF4133 PF13571.6 ORY02839.1 - 0.0028 17.9 0.4 0.0028 17.9 0.4 1.8 2 1 0 2 2 2 1 Domain of unknown function (DUF4133) Amidase PF01425.21 ORY02840.1 - 7.7e-91 305.3 0.0 1.1e-90 304.7 0.0 1.2 1 1 0 1 1 1 1 Amidase MFS_1 PF07690.16 ORY02841.1 - 9.8e-33 113.5 27.6 9.8e-33 113.5 27.6 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF4337 PF14235.6 ORY02841.1 - 1.4 9.0 0.0 1.4 9.0 0.0 2.5 3 1 0 3 3 3 0 Domain of unknown function (DUF4337) Fungal_trans_2 PF11951.8 ORY02842.1 - 1.4e-06 27.4 1.0 4.7e-06 25.7 1.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY02842.1 - 0.0093 16.1 12.9 0.016 15.3 12.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 ORY02843.1 - 2.9e-44 151.5 42.1 2.9e-44 151.5 42.1 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 ORY02843.1 - 1e-20 73.8 15.4 1.8e-20 72.9 15.4 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 ORY02843.1 - 9.6e-07 28.0 4.3 9.6e-07 28.0 4.3 4.5 1 1 3 4 4 4 3 Sugar (and other) transporter MFS_2 PF13347.6 ORY02843.1 - 0.067 11.7 35.5 0.051 12.1 5.1 4.1 2 1 2 4 4 4 0 MFS/sugar transport protein OGFr_III PF04680.13 ORY02844.1 - 0.0042 17.6 8.8 14 6.5 0.1 4.7 5 0 0 5 5 5 3 Opioid growth factor receptor repeat MazG PF03819.17 ORY02844.1 - 0.011 15.9 0.4 13 6.0 0.1 3.7 3 2 0 3 3 3 0 MazG nucleotide pyrophosphohydrolase domain Pox_A_type_inc PF04508.12 ORY02844.1 - 0.15 12.0 3.6 1.3 9.0 0.1 2.5 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat Microtub_bind PF13931.6 ORY02844.1 - 2.7 8.4 4.5 3e+02 1.7 0.0 4.3 5 0 0 5 5 5 0 Kinesin-associated microtubule-binding DUF3328 PF11807.8 ORY02845.1 - 1.2e-22 80.8 0.2 2e-22 80.1 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Acetyltransf_1 PF00583.25 ORY02847.1 - 6.5e-07 29.6 0.0 9.2e-07 29.1 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ORY02847.1 - 2.1e-06 28.1 0.0 3e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ORY02847.1 - 2.9e-06 27.2 0.0 5.1e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain AA_permease_2 PF13520.6 ORY02848.1 - 3.1e-50 171.3 49.6 3.8e-50 171.0 49.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ORY02848.1 - 3.2e-27 95.3 42.4 4.3e-27 94.8 42.4 1.1 1 0 0 1 1 1 1 Amino acid permease FAD_binding_4 PF01565.23 ORY02849.1 - 6.3e-23 81.1 1.7 1.3e-22 80.1 1.7 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 ORY02849.1 - 1.8e-07 31.1 0.1 4.4e-07 29.9 0.1 1.7 1 0 0 1 1 1 1 Berberine and berberine like CBM_1 PF00734.18 ORY02850.1 - 5.8e-12 45.4 12.4 5.8e-12 45.4 12.4 2.4 2 0 0 2 2 2 1 Fungal cellulose binding domain DPBB_1 PF03330.18 ORY02850.1 - 0.0089 16.3 0.1 0.0089 16.3 0.1 3.3 3 1 0 3 3 3 1 Lytic transglycolase MSP1_C PF07462.11 ORY02850.1 - 1.3 7.6 3.0 1.6 7.3 3.0 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus F-box-like PF12937.7 ORY02851.1 - 3e-07 30.2 0.2 1.2e-06 28.3 0.2 2.1 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY02851.1 - 0.0021 17.9 0.4 0.0056 16.5 0.0 2.0 2 0 0 2 2 2 1 F-box domain F-box_4 PF15966.5 ORY02851.1 - 0.0038 17.1 0.1 0.044 13.7 0.0 2.5 1 1 1 2 2 2 1 F-box Bac_rhamnosid_C PF17390.2 ORY02852.1 - 1.3e-07 31.3 0.0 2.5e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain Bac_rhamnosid6H PF17389.2 ORY02852.1 - 0.031 13.5 0.1 3.2 6.9 0.0 3.0 2 1 1 3 3 3 0 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Glyco_hydro_36 PF17167.4 ORY02852.1 - 0.18 10.5 0.0 0.32 9.6 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase 36 superfamily, catalytic domain DUF3117 PF11314.8 ORY02852.1 - 0.2 11.5 0.0 0.47 10.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3117) Ank_2 PF12796.7 ORY02854.1 - 1.4e-37 128.1 1.0 1.5e-11 44.7 0.3 6.4 2 2 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY02854.1 - 2.2e-37 127.0 4.2 2.1e-06 28.2 0.0 9.2 6 3 4 10 10 10 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY02854.1 - 1.6e-32 107.9 5.2 0.0033 17.8 0.0 11.9 12 0 0 12 12 12 7 Ankyrin repeat Ank PF00023.30 ORY02854.1 - 7.9e-17 60.9 1.7 0.093 13.2 0.0 9.0 9 0 0 9 9 9 4 Ankyrin repeat Clr5 PF14420.6 ORY02854.1 - 3.4e-15 56.0 8.3 9.4e-15 54.6 8.3 1.8 1 0 0 1 1 1 1 Clr5 domain Ank_5 PF13857.6 ORY02854.1 - 2.8e-12 46.6 4.6 0.021 15.1 0.0 8.0 4 2 4 8 8 8 3 Ankyrin repeats (many copies) DUF3447 PF11929.8 ORY02854.1 - 7e-05 22.7 2.9 3.8 7.5 1.0 4.8 5 1 0 5 5 5 2 Domain of unknown function (DUF3447) Grg1 PF11034.8 ORY02856.1 - 1.3e-27 95.7 9.4 1.6e-27 95.5 9.4 1.1 1 0 0 1 1 1 1 Glucose-repressible protein Grg1 AAA PF00004.29 ORY02917.1 - 1.9e-40 138.3 0.0 3.8e-40 137.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 ORY02917.1 - 3e-19 68.7 0.4 5.8e-19 67.8 0.4 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 ORY02917.1 - 4.5e-07 29.6 0.0 1e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 ORY02917.1 - 0.00014 22.3 1.6 0.018 15.4 0.0 2.9 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 ORY02917.1 - 0.00016 21.7 1.0 0.00049 20.1 0.1 2.3 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 ORY02917.1 - 0.00028 20.7 0.0 0.00068 19.4 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 ORY02917.1 - 0.00099 19.3 0.5 0.01 15.9 0.0 2.8 3 1 0 3 3 3 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 ORY02917.1 - 0.0012 19.1 1.7 0.075 13.3 0.0 3.0 2 1 1 3 3 3 1 AAA domain PhoH PF02562.16 ORY02917.1 - 0.0045 16.5 0.2 0.075 12.5 0.1 2.3 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.21 ORY02917.1 - 0.0061 16.0 0.1 0.019 14.4 0.0 1.8 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI CLZ PF16526.5 ORY02917.1 - 0.0075 16.6 5.0 0.042 14.2 5.0 2.4 1 0 0 1 1 1 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels AAA_33 PF13671.6 ORY02917.1 - 0.013 15.7 0.0 0.031 14.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 ORY02917.1 - 0.014 14.6 0.7 0.028 13.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 ORY02917.1 - 0.076 12.7 0.1 0.17 11.6 0.1 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.6 ORY02917.1 - 0.079 12.7 0.2 0.25 11.1 0.0 2.1 2 1 0 2 2 1 0 AAA domain AAA_18 PF13238.6 ORY02917.1 - 0.085 13.4 0.7 3.5 8.2 0.0 2.9 2 1 0 2 2 2 0 AAA domain AAA_7 PF12775.7 ORY02917.1 - 0.11 12.1 0.0 0.34 10.4 0.0 1.9 1 1 0 1 1 1 0 P-loop containing dynein motor region TMF_TATA_bd PF12325.8 ORY02917.1 - 0.34 11.1 6.9 0.081 13.2 1.9 2.4 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding AAA_11 PF13086.6 ORY02917.1 - 0.41 10.4 0.0 0.41 10.4 0.0 2.7 2 1 1 3 3 3 0 AAA domain TauD PF02668.16 ORY02918.1 - 1.5e-40 139.7 0.0 2.3e-40 139.1 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 ORY02918.1 - 1.2e-14 54.7 0.0 8.3e-14 52.0 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF971) CsiD PF08943.10 ORY02918.1 - 0.033 13.3 0.0 0.49 9.5 0.0 2.1 2 0 0 2 2 2 0 CsiD ECH_1 PF00378.20 ORY02919.1 - 6.2e-70 235.4 0.1 7.8e-70 235.0 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ORY02919.1 - 2.1e-32 113.0 0.5 8e-30 104.5 0.3 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Rer1 PF03248.13 ORY02920.1 - 1.5e-76 255.9 4.8 1.7e-76 255.7 4.8 1.0 1 0 0 1 1 1 1 Rer1 family Ferric_reduct PF01794.19 ORY02921.1 - 2.4e-19 69.7 10.2 5e-19 68.6 10.2 1.6 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 ORY02921.1 - 4.8e-07 29.8 0.1 4.8e-07 29.8 0.1 2.9 2 1 1 3 3 3 1 FAD-binding domain NAD_binding_6 PF08030.12 ORY02921.1 - 0.00051 20.2 0.0 0.039 14.1 0.0 2.3 2 0 0 2 2 2 1 Ferric reductase NAD binding domain TssN PF17555.2 ORY02921.1 - 1.1 8.6 12.6 0.39 10.1 5.4 2.1 2 0 0 2 2 2 0 Type VI secretion system, TssN Collagen_mid PF15984.5 ORY02922.1 - 0.0006 19.6 13.1 0.00065 19.5 13.1 1.0 1 0 0 1 1 1 1 Bacterial collagen, middle region Chlorosome_CsmC PF11098.8 ORY02922.1 - 0.042 13.8 7.0 0.052 13.5 7.0 1.1 1 0 0 1 1 1 0 Chlorosome envelope protein C MIF4G PF02854.19 ORY02923.1 - 9.3e-49 165.9 0.0 9.3e-49 165.9 0.0 1.7 2 0 0 2 2 2 1 MIF4G domain eIF_4G1 PF12152.8 ORY02923.1 - 5.6e-22 77.7 0.4 5.6e-22 77.7 0.4 2.3 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 4G1 DUF4880 PF16220.5 ORY02924.1 - 0.058 13.3 1.6 0.058 13.3 1.6 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4880) Homeodomain PF00046.29 ORY02927.1 - 5.8e-17 61.3 3.8 1.1e-16 60.4 3.8 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 ORY02927.1 - 0.023 14.6 0.1 0.054 13.4 0.1 1.6 1 0 0 1 1 1 0 Homeobox KN domain efThoc1 PF11957.8 ORY02928.1 - 4.9e-111 371.8 0.1 6.1e-111 371.5 0.1 1.0 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor SWIRM PF04433.17 ORY02928.1 - 0.1 13.0 0.1 0.3 11.4 0.1 1.8 1 0 0 1 1 1 0 SWIRM domain Swi3 PF07962.12 ORY02929.1 - 3.6e-31 107.0 0.4 5.3e-31 106.4 0.4 1.3 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 DSHCT PF08148.12 ORY02930.1 - 1.4e-50 171.2 0.3 3e-50 170.1 0.3 1.6 1 0 0 1 1 1 1 DSHCT (NUC185) domain Ski2_N PF17911.1 ORY02930.1 - 1.8e-39 134.6 0.0 3.8e-39 133.6 0.0 1.5 1 0 0 1 1 1 1 Ski2 N-terminal region rRNA_proc-arch PF13234.6 ORY02930.1 - 9.3e-22 78.2 0.1 1.5e-21 77.5 0.1 1.4 1 0 0 1 1 1 1 rRNA-processing arch domain DEAD PF00270.29 ORY02930.1 - 8.4e-18 64.7 0.0 5e-17 62.2 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY02930.1 - 1.1e-06 28.9 0.0 3.8e-06 27.2 0.0 2.0 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY02930.1 - 5.9e-05 23.1 0.0 0.00012 22.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit IBN_N PF03810.19 ORY02931.1 - 4.3e-13 49.0 0.0 4.8e-11 42.4 0.0 3.1 2 0 0 2 2 2 1 Importin-beta N-terminal domain Cse1 PF08506.10 ORY02931.1 - 1.6e-05 23.9 0.3 9.4e-05 21.4 0.0 2.3 2 0 0 2 2 2 1 Cse1 Xpo1 PF08389.12 ORY02931.1 - 0.0051 16.9 3.1 0.4 10.7 0.1 4.3 4 1 1 5 5 5 1 Exportin 1-like protein RTP1_C1 PF10363.9 ORY02931.1 - 0.016 15.4 0.5 0.34 11.1 0.1 2.8 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 RIX1 PF08167.12 ORY02931.1 - 0.13 12.0 0.5 3 7.6 0.0 3.3 3 0 0 3 3 3 0 rRNA processing/ribosome biogenesis MOR2-PAG1_C PF14225.6 ORY02931.1 - 0.13 12.0 0.8 1.5 8.6 0.1 2.7 2 0 0 2 2 2 0 Cell morphogenesis C-terminal HEAT_EZ PF13513.6 ORY02931.1 - 0.3 11.6 2.7 44 4.7 0.4 4.8 5 0 0 5 5 5 0 HEAT-like repeat Astro_capsid_p PF12226.8 ORY02931.1 - 2.7 7.0 9.8 5 6.2 9.8 1.4 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Pyr_redox_2 PF07992.14 ORY02932.1 - 1.9e-19 70.0 0.0 1.2e-16 60.8 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 ORY02932.1 - 1.1e-16 60.4 0.7 6.5e-16 57.8 0.0 2.0 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 ORY02932.1 - 1.5e-15 57.3 0.0 9.2e-14 51.4 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ORY02932.1 - 1e-11 44.6 0.0 7.7e-10 38.4 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 ORY02932.1 - 1.7e-10 41.0 0.0 7.5e-07 29.3 0.0 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 ORY02932.1 - 4.8e-07 29.9 0.6 2.8 7.9 0.0 4.4 4 1 0 4 4 4 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 ORY02932.1 - 1.3e-05 24.5 0.0 0.013 14.6 0.0 2.8 2 1 0 2 2 2 2 Lycopene cyclase protein Pyr_redox PF00070.27 ORY02932.1 - 2.7e-05 24.6 1.3 0.012 16.1 0.0 2.8 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ORY02932.1 - 0.00057 19.1 0.0 0.055 12.5 0.0 2.8 3 0 0 3 3 3 1 FAD binding domain DAO PF01266.24 ORY02932.1 - 0.00072 19.2 2.3 0.57 9.7 0.2 3.5 2 2 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.14 ORY02932.1 - 0.0035 16.1 0.9 4.2 6.0 0.1 3.1 3 0 0 3 3 3 2 HI0933-like protein Thi4 PF01946.17 ORY02932.1 - 0.0062 15.8 0.3 0.75 9.0 0.0 2.3 2 0 0 2 2 2 1 Thi4 family 2-Hacid_dh_C PF02826.19 ORY02932.1 - 0.0083 15.5 0.0 0.06 12.7 0.0 2.1 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 ORY02932.1 - 0.0096 16.0 0.1 0.097 12.7 0.1 2.2 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 ORY02932.1 - 0.018 14.9 0.0 0.084 12.7 0.0 2.0 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 ORY02932.1 - 0.027 13.7 0.1 0.32 10.2 0.0 2.3 2 0 0 2 2 2 0 FAD binding domain NAD_binding_7 PF13241.6 ORY02932.1 - 0.084 13.3 0.0 0.34 11.4 0.0 2.0 2 0 0 2 2 2 0 Putative NAD(P)-binding GIDA PF01134.22 ORY02932.1 - 0.088 11.9 0.0 58 2.6 0.0 3.6 4 0 0 4 4 4 0 Glucose inhibited division protein A NAD_Gly3P_dh_N PF01210.23 ORY02932.1 - 0.13 12.2 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.15 ORY02932.1 - 0.15 12.3 0.0 0.33 11.1 0.0 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase ThiF PF00899.21 ORY02932.1 - 0.19 11.1 0.1 17 4.7 0.0 2.4 2 0 0 2 2 2 0 ThiF family TrkA_N PF02254.18 ORY02932.1 - 0.37 11.1 1.0 3.5 7.9 0.0 2.9 3 0 0 3 3 3 0 TrkA-N domain SAP PF02037.27 ORY02933.1 - 1.1e-05 25.1 6.6 1.6e-05 24.6 0.5 3.0 3 0 0 3 3 3 1 SAP domain Myb_DNA-binding PF00249.31 ORY02933.1 - 0.0054 16.9 0.1 0.019 15.1 0.1 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORY02933.1 - 0.046 14.0 0.4 0.16 12.2 0.1 2.1 2 0 0 2 2 2 0 Myb-like DNA-binding domain Herpes_pp85 PF04637.12 ORY02934.1 - 0.5 8.7 2.8 0.42 9.0 2.8 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) SR-25 PF10500.9 ORY02934.1 - 1.1 8.9 9.1 1 8.9 9.1 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein UPF0184 PF03670.13 ORY02935.1 - 0.038 14.4 0.5 0.097 13.1 0.5 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0184) BT1 PF03092.16 ORY02935.1 - 0.14 10.4 0.0 0.21 9.8 0.0 1.2 1 0 0 1 1 1 0 BT1 family POX PF07526.11 ORY02935.1 - 0.18 12.4 5.5 0.059 14.0 1.8 2.0 2 0 0 2 2 2 0 Associated with HOX Methyltransf_23 PF13489.6 ORY02936.1 - 1.4e-23 83.6 0.0 1.9e-23 83.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY02936.1 - 3.6e-13 50.0 0.0 8.6e-13 48.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY02936.1 - 5.8e-11 42.4 0.0 2.3e-10 40.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY02936.1 - 8.6e-10 39.1 0.0 1.8e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY02936.1 - 4.5e-07 30.5 0.0 1.5e-06 28.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 ORY02936.1 - 1.5e-05 25.2 0.0 2.6e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.14 ORY02936.1 - 0.0011 18.5 0.0 0.0018 17.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 ORY02936.1 - 0.0064 16.0 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Ubie_methyltran PF01209.18 ORY02936.1 - 0.0091 15.4 0.0 0.081 12.2 0.0 2.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 ORY02936.1 - 0.025 13.9 0.0 0.046 13.0 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.11 ORY02936.1 - 0.026 13.4 0.0 0.61 9.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) PrmA PF06325.13 ORY02936.1 - 0.028 13.8 0.0 0.045 13.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_2 PF00891.18 ORY02936.1 - 0.12 11.6 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain p450 PF00067.22 ORY02937.1 - 1.4e-42 146.1 0.0 1.7e-42 145.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAR1 PF03101.15 ORY02938.1 - 6.9e-08 33.1 0.4 1.5e-07 32.0 0.4 1.5 1 0 0 1 1 1 1 FAR1 DNA-binding domain Laminin_II PF06009.12 ORY02938.1 - 0.044 13.8 3.2 0.26 11.3 0.1 2.3 2 0 0 2 2 2 0 Laminin Domain II BAR_2 PF10455.9 ORY02938.1 - 0.092 11.9 4.4 0.053 12.7 1.9 1.7 1 1 1 2 2 2 0 Bin/amphiphysin/Rvs domain for vesicular trafficking HIP1_clath_bdg PF16515.5 ORY02938.1 - 0.17 12.5 7.0 0.23 12.1 5.8 1.8 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 PFK PF00365.20 ORY02939.1 - 7e-190 629.3 1.8 3.8e-108 361.1 0.3 2.0 2 0 0 2 2 2 2 Phosphofructokinase DAGK_cat PF00781.24 ORY02939.1 - 0.054 13.1 0.4 0.38 10.4 0.2 2.6 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain ADH_zinc_N PF00107.26 ORY02940.1 - 8e-15 55.0 0.0 1.5e-14 54.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ORY02940.1 - 0.095 12.6 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain MRJP PF03022.16 ORY02941.1 - 1.8e-29 103.0 0.0 4.1e-29 101.8 0.0 1.4 1 1 0 1 1 1 1 Major royal jelly protein SGL PF08450.12 ORY02941.1 - 0.011 15.4 0.0 0.027 14.0 0.0 1.7 1 0 0 1 1 1 0 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 ORY02941.1 - 0.047 13.8 1.6 19 5.5 0.0 4.7 4 2 0 4 4 4 0 NHL repeat Med17 PF10156.9 ORY02942.1 - 1.8e-76 257.8 0.0 2.2e-76 257.4 0.0 1.1 1 0 0 1 1 1 1 Subunit 17 of Mediator complex ISN1 PF06437.11 ORY02943.1 - 2e-193 642.9 0.0 2.3e-193 642.7 0.0 1.0 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase Ndc80_HEC PF03801.13 ORY02945.1 - 4.8e-58 195.1 0.9 1.1e-57 193.9 0.9 1.7 1 0 0 1 1 1 1 HEC/Ndc80p family DHR10 PF18595.1 ORY02945.1 - 0.0086 16.1 13.7 0.0086 16.1 13.7 5.5 4 2 1 5 5 5 1 Designed helical repeat protein 10 domain AKNA PF12443.8 ORY02945.1 - 0.076 13.7 6.4 0.99 10.1 0.3 4.6 3 1 0 3 3 3 0 AT-hook-containing transcription factor NPV_P10 PF05531.12 ORY02945.1 - 0.48 10.9 8.6 6.2 7.4 0.6 4.2 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Baculo_F PF12259.8 ORY02945.1 - 6.3 5.2 14.8 0.035 12.7 3.9 2.4 2 1 0 2 2 2 0 Baculovirus F protein DUF3584 PF12128.8 ORY02945.1 - 6.8 4.1 40.3 0.54 7.7 12.8 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3584) DUF4094 PF13334.6 ORY02945.1 - 9.5 6.7 16.6 28 5.2 2.9 4.4 3 2 1 4 4 4 0 Domain of unknown function (DUF4094) ATP-grasp_2 PF08442.10 ORY02946.1 - 4.2e-77 258.3 0.8 4.2e-77 258.3 0.8 1.7 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.19 ORY02946.1 - 6e-26 91.1 0.2 1.2e-25 90.1 0.2 1.5 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 ORY02946.1 - 2.4e-10 40.2 0.4 5.7e-10 39.0 0.4 1.7 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 ORY02946.1 - 0.00021 21.1 1.3 0.0048 16.7 0.2 2.5 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain VID27_N PF17748.1 ORY02946.1 - 0.074 12.9 0.5 0.13 12.1 0.5 1.3 1 0 0 1 1 1 0 VID27 N-terminal region DUF3245 PF11595.8 ORY02947.1 - 5.4e-15 56.1 0.4 5.4e-15 56.1 0.4 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3245) Thiolase_N PF00108.23 ORY02948.1 - 3.2e-74 249.6 0.7 4.3e-74 249.2 0.7 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 ORY02948.1 - 1.6e-40 137.6 0.4 4.3e-40 136.2 0.4 1.7 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 ORY02948.1 - 5e-05 23.0 0.2 0.00012 21.8 0.2 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain NTF2 PF02136.20 ORY02949.1 - 5.1e-31 107.7 0.1 5.7e-31 107.6 0.1 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4440 PF14534.6 ORY02949.1 - 2.7e-06 27.8 0.0 3.2e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) MFS_1 PF07690.16 ORY02950.1 - 3.6e-29 101.8 25.0 3.6e-29 101.8 25.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY02950.1 - 4.9e-09 35.6 6.5 4.9e-09 35.6 6.5 1.9 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.7 ORY02950.1 - 0.00031 19.7 2.8 0.00031 19.7 2.8 2.2 3 0 0 3 3 3 1 MFS_1 like family Tom6 PF17112.5 ORY02951.1 - 3.2e-05 23.3 0.0 3.5e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom6, fungal TPR_1 PF00515.28 ORY02953.1 - 4.3e-16 58.0 9.6 1e-06 28.3 0.0 4.9 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 ORY02953.1 - 1.3e-14 53.1 8.2 4.6e-05 23.2 0.0 5.0 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_12 PF13424.6 ORY02953.1 - 1.6e-09 37.9 0.2 1.1e-05 25.6 0.0 3.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 ORY02953.1 - 2.9e-09 36.4 0.7 0.0012 18.9 0.0 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat PB1 PF00564.24 ORY02953.1 - 6.3e-08 32.4 0.1 1.3e-07 31.4 0.1 1.5 1 0 0 1 1 1 1 PB1 domain TPR_6 PF13174.6 ORY02953.1 - 2.1e-07 31.1 0.1 1.6 9.5 0.0 4.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 ORY02953.1 - 5.5e-07 29.2 0.6 0.00013 21.5 0.1 3.7 2 1 1 3 3 3 1 TPR repeat TPR_7 PF13176.6 ORY02953.1 - 6e-07 29.1 3.0 0.00013 21.7 0.0 4.1 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 ORY02953.1 - 0.0013 19.3 1.9 0.054 14.1 0.1 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 ORY02953.1 - 0.0014 18.7 0.8 0.29 11.3 0.1 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 ORY02953.1 - 0.003 18.3 1.4 0.79 10.7 0.1 3.6 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_4 PF07721.14 ORY02953.1 - 0.0034 17.9 2.3 40 5.3 0.0 5.3 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 ORY02953.1 - 0.031 14.2 3.2 5.3 7.0 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.6 ORY02953.1 - 0.048 14.1 0.5 3.2 8.3 0.0 3.5 4 0 0 4 4 3 0 Tetratricopeptide repeat SIN1 PF05422.12 ORY02953.1 - 0.27 11.8 8.5 0.65 10.5 7.4 2.2 2 0 0 2 2 2 0 Stress-activated map kinase interacting protein 1 (SIN1) SPATA48 PF15073.6 ORY02953.1 - 1.9 8.8 7.2 23 5.3 0.3 3.3 2 1 1 3 3 3 0 Spermatogenesis-associated protein 48 HMA PF00403.26 ORY02954.1 - 7.1e-13 48.8 0.0 1.3e-12 48.0 0.0 1.4 1 0 0 1 1 1 1 Heavy-metal-associated domain Sod_Cu PF00080.20 ORY02954.1 - 1.2e-09 38.4 0.0 2.1e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Ribosomal_L13 PF00572.18 ORY02955.1 - 1.2e-40 138.7 0.0 1.6e-40 138.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L13 Uricase PF01014.18 ORY02956.1 - 6.7e-76 252.8 1.2 6.3e-40 136.5 0.5 2.0 2 0 0 2 2 2 2 Uricase RICTOR_N PF14664.6 ORY02958.1 - 1.7e-135 451.8 1.0 2.6e-134 447.9 0.1 2.9 3 1 1 4 4 4 1 Rapamycin-insensitive companion of mTOR, N-term RasGEF_N_2 PF14663.6 ORY02958.1 - 5.7e-40 136.1 0.1 5.6e-36 123.2 0.0 3.8 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_M PF14666.6 ORY02958.1 - 7.4e-36 122.1 0.3 5.9e-33 112.7 0.0 3.6 4 1 1 5 5 5 2 Rapamycin-insensitive companion of mTOR, middle domain RICTOR_V PF14668.6 ORY02958.1 - 1.3e-28 99.0 0.3 7.2e-27 93.4 0.2 3.5 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.16 ORY02958.1 - 8.3e-13 48.3 13.8 1.8e-12 47.2 13.3 1.9 2 0 0 2 2 2 1 Hr1 repeat LON_substr_bdg PF02190.16 ORY02959.1 - 1.7e-29 103.2 0.0 2.5e-29 102.7 0.0 1.2 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain zf-RING_UBOX PF13445.6 ORY02959.1 - 3.7e-12 46.1 24.2 1.4e-05 25.0 7.1 3.7 3 0 0 3 3 3 2 RING-type zinc-finger zf-C3HC4_2 PF13923.6 ORY02959.1 - 6.7e-12 45.0 23.3 1.9e-09 37.2 13.9 2.6 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 ORY02959.1 - 7.1e-11 42.1 18.1 4.4e-05 23.5 9.4 3.3 2 1 1 3 3 3 2 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 ORY02959.1 - 8e-09 35.2 22.4 6.4e-05 22.7 13.6 2.6 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORY02959.1 - 3.2e-08 33.4 25.3 0.00011 22.0 12.6 2.6 2 0 0 2 2 2 2 zinc-RING finger domain zf-RING_2 PF13639.6 ORY02959.1 - 5.9e-08 32.9 25.5 2.9e-06 27.5 13.3 2.7 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4_3 PF13920.6 ORY02959.1 - 1.7e-07 31.0 22.0 4.9e-05 23.1 12.5 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 ORY02959.1 - 8.3e-05 22.4 22.8 0.0017 18.2 11.5 2.6 2 1 0 2 2 2 2 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 ORY02959.1 - 0.00034 20.3 11.4 0.0036 17.0 7.9 3.2 2 1 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-RING_10 PF16685.5 ORY02959.1 - 0.00038 20.5 18.9 0.0025 17.9 8.9 2.6 2 0 0 2 2 2 2 zinc RING finger of MSL2 Baculo_IE-1 PF05290.11 ORY02959.1 - 0.0015 18.5 2.3 0.0015 18.5 2.3 2.0 2 0 0 2 2 2 1 Baculovirus immediate-early protein (IE-0) zf-P11 PF03854.14 ORY02959.1 - 0.012 15.3 10.3 0.012 15.3 10.3 3.2 2 1 0 2 2 2 0 P-11 zinc finger U-box PF04564.15 ORY02959.1 - 0.086 13.0 0.1 0.26 11.5 0.1 1.8 1 0 0 1 1 1 0 U-box domain zf-rbx1 PF12678.7 ORY02959.1 - 0.18 12.1 14.2 0.13 12.6 8.3 2.7 2 0 0 2 2 2 0 RING-H2 zinc finger domain RCC1 PF00415.18 ORY02960.1 - 1.4e-65 217.7 0.0 1.1e-10 42.0 0.0 7.6 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 ORY02960.1 - 3.6e-37 125.4 27.3 7.2e-08 32.0 0.9 6.5 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat sCache_3_2 PF17203.4 ORY02960.1 - 0.0063 16.6 0.0 0.89 9.7 0.0 2.4 2 0 0 2 2 2 2 Single cache domain 3 Metallophos PF00149.28 ORY02961.1 - 1.3e-11 45.4 5.6 1.5e-11 45.2 5.6 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Forkhead PF00250.18 ORY03026.1 - 7.2e-23 80.7 0.3 1.2e-22 79.9 0.3 1.4 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 ORY03026.1 - 3e-07 30.7 0.0 7.4e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 FHA domain MukF_M PF17192.4 ORY03026.1 - 0.15 11.8 0.1 0.27 11.0 0.1 1.2 1 0 0 1 1 1 0 MukF middle domain Snf7 PF03357.21 ORY03027.1 - 9.4e-40 136.0 16.9 9.4e-40 136.0 16.9 2.0 2 0 0 2 2 2 1 Snf7 Phage_lysozyme2 PF18013.1 ORY03027.1 - 0.13 12.3 3.6 0.14 12.1 1.3 2.1 1 1 1 2 2 2 0 Phage tail lysozyme DUF3138 PF11336.8 ORY03027.1 - 1 7.9 6.5 0.88 8.1 3.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3138) Allexi_40kDa PF05549.11 ORY03027.1 - 1.1 8.7 6.0 1.6 8.2 6.0 1.4 1 1 0 1 1 1 0 Allexivirus 40kDa protein DASH_Spc19 PF08287.11 ORY03027.1 - 8.6 6.2 19.6 3.6 7.5 7.8 2.2 2 0 0 2 2 2 0 Spc19 Ten1 PF12658.7 ORY03028.1 - 5.4e-34 116.8 0.0 5.9e-34 116.6 0.0 1.0 1 0 0 1 1 1 1 Telomere capping, CST complex subunit Ten1_2 PF15490.6 ORY03028.1 - 3e-07 30.2 0.0 3.5e-07 30.0 0.0 1.0 1 0 0 1 1 1 1 Telomere-capping, CST complex subunit Rep_fac-A_3 PF08661.11 ORY03028.1 - 0.0026 18.1 0.0 0.004 17.5 0.0 1.4 1 1 0 1 1 1 1 Replication factor A protein 3 DUF4360 PF14273.6 ORY03030.1 - 2e-49 167.9 4.5 2.3e-49 167.7 4.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) NPCBM_assoc PF10633.9 ORY03030.1 - 0.045 14.0 0.0 0.12 12.6 0.0 1.8 1 0 0 1 1 1 0 NPCBM-associated, NEW3 domain of alpha-galactosidase Lpp-LpqN PF10738.9 ORY03030.1 - 0.11 12.0 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Probable lipoprotein LpqN Glyco_hydro_11 PF00457.17 ORY03032.1 - 1.7e-62 210.2 6.4 2e-62 209.9 6.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 DUF4231 PF14015.6 ORY03033.1 - 0.024 15.1 5.4 0.13 12.7 0.3 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF4231) MARVEL PF01284.23 ORY03033.1 - 0.035 14.1 8.5 0.12 12.4 8.7 1.8 1 1 0 1 1 1 0 Membrane-associating domain DUF5336 PF17270.2 ORY03033.1 - 0.97 9.0 7.0 0.91 9.1 0.9 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF5336) FA_desaturase PF00487.24 ORY03033.1 - 1 9.1 7.8 0.25 11.2 5.0 1.4 1 1 0 1 1 1 0 Fatty acid desaturase Molybdop_Fe4S4 PF04879.16 ORY03034.1 - 0.092 12.8 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin oxidoreductase Fe4S4 domain p450 PF00067.22 ORY03036.1 - 2.1e-63 214.7 0.0 2.5e-63 214.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 He_PIG_assoc PF10632.9 ORY03036.1 - 0.045 13.4 1.6 0.32 10.7 0.0 2.6 3 0 0 3 3 3 0 He_PIG associated, NEW1 domain of bacterial glycohydrolase IRK_N PF08466.10 ORY03036.1 - 0.099 12.8 0.2 0.98 9.6 0.0 2.5 2 1 0 2 2 2 0 Inward rectifier potassium channel N-terminal ketoacyl-synt PF00109.26 ORY03037.1 - 2.2e-51 174.9 0.0 3.2e-51 174.3 0.0 1.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 ORY03037.1 - 1.6e-24 86.2 0.1 2.7e-24 85.4 0.1 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 ORY03037.1 - 1.3e-05 24.7 0.2 2.1e-05 24.0 0.2 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain EthD PF07110.11 ORY03038.1 - 0.008 17.3 0.5 0.021 16.0 0.5 1.6 1 1 0 1 1 1 1 EthD domain DUF3455 PF11937.8 ORY03040.1 - 3.5e-33 115.2 0.0 4.1e-33 115.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) Methyltransf_23 PF13489.6 ORY03041.1 - 0.013 15.3 0.0 0.03 14.1 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain TRI12 PF06609.13 ORY03042.1 - 5.2e-46 157.3 17.9 6e-46 157.1 17.9 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 ORY03042.1 - 4.6e-18 65.3 37.0 4.6e-18 65.3 37.0 2.5 2 2 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY03042.1 - 3.5e-09 36.0 6.0 3.5e-09 36.0 6.0 2.7 3 0 0 3 3 3 1 Sugar (and other) transporter Neurensin PF14927.6 ORY03042.1 - 0.078 12.7 0.6 3.6 7.3 0.0 3.2 3 0 0 3 3 3 0 Neurensin DUF3328 PF11807.8 ORY03044.1 - 7.5e-18 65.1 3.3 9.7e-18 64.7 2.4 1.7 1 1 1 2 2 2 1 Domain of unknown function (DUF3328) Aminotran_4 PF01063.19 ORY03046.1 - 1.5e-15 57.7 0.0 1.5e-09 38.0 0.0 3.0 3 0 0 3 3 3 2 Amino-transferase class IV TPR_1 PF00515.28 ORY03047.1 - 3.6e-33 112.0 29.3 0.00047 19.9 0.2 11.3 11 0 0 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.17 ORY03047.1 - 4.6e-33 110.6 27.7 0.00022 21.1 0.1 11.4 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_16 PF13432.6 ORY03047.1 - 2.2e-18 66.6 12.7 1.6e-05 25.4 0.5 6.9 6 1 1 7 7 7 5 Tetratricopeptide repeat TPR_17 PF13431.6 ORY03047.1 - 1e-17 63.2 11.6 0.0036 17.6 0.0 9.0 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_8 PF13181.6 ORY03047.1 - 1.3e-17 62.5 32.0 0.011 15.9 0.1 10.6 11 0 0 11 11 10 5 Tetratricopeptide repeat TPR_11 PF13414.6 ORY03047.1 - 1.2e-16 60.1 22.3 0.00068 19.3 0.0 8.4 7 1 1 8 8 8 6 TPR repeat TPR_12 PF13424.6 ORY03047.1 - 1e-12 48.2 25.7 0.0031 17.8 0.4 8.3 3 1 5 8 8 8 5 Tetratricopeptide repeat TPR_9 PF13371.6 ORY03047.1 - 3.8e-10 39.8 4.5 0.00019 21.5 0.1 4.7 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 ORY03047.1 - 1.9e-09 37.9 23.6 3.5e-05 24.2 0.2 6.8 5 1 4 9 9 8 4 Tetratricopeptide repeat TPR_14 PF13428.6 ORY03047.1 - 1.3e-08 35.0 17.4 0.032 15.1 0.3 7.8 5 2 4 9 9 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 ORY03047.1 - 1.4e-06 27.9 18.3 0.051 13.6 0.1 8.4 8 1 1 9 9 9 2 Tetratricopeptide repeat TPR_10 PF13374.6 ORY03047.1 - 3.7e-06 26.6 19.7 0.029 14.2 0.2 8.0 9 0 0 9 9 8 1 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY03047.1 - 3.4e-05 24.0 12.1 0.15 12.3 0.2 4.9 3 1 2 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_MalT PF17874.1 ORY03047.1 - 3.8e-05 23.2 1.3 7.3e-05 22.3 0.6 1.8 1 1 0 1 1 1 1 MalT-like TPR region SHNi-TPR PF10516.9 ORY03047.1 - 0.00083 18.8 6.7 1.5 8.3 0.0 5.5 5 0 0 5 5 5 2 SHNi-TPR MAS20 PF02064.15 ORY03047.1 - 0.0034 17.5 7.2 0.24 11.5 0.9 4.0 3 1 1 4 4 4 1 MAS20 protein import receptor Sel1 PF08238.12 ORY03047.1 - 0.0048 17.5 3.7 1.7 9.5 0.0 4.1 4 0 0 4 4 3 1 Sel1 repeat DUF3856 PF12968.7 ORY03047.1 - 0.005 16.9 6.8 4.9 7.2 0.0 5.4 4 1 1 5 5 5 1 Domain of Unknown Function (DUF3856) TAF1_subA PF14929.6 ORY03047.1 - 0.026 14.0 1.2 0.085 12.3 0.3 2.2 2 1 0 2 2 2 0 TAF RNA Polymerase I subunit A Phage_CP76 PF06892.11 ORY03047.1 - 0.049 13.2 0.0 0.13 11.8 0.0 1.7 1 0 0 1 1 1 0 Phage regulatory protein CII (CP76) DUF3808 PF10300.9 ORY03047.1 - 0.1 11.3 4.3 1.4 7.5 0.0 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF3808) TPR_6 PF13174.6 ORY03047.1 - 1.4 9.7 19.9 13 6.7 0.5 7.4 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_3 PF07720.12 ORY03047.1 - 4.4 7.4 11.3 26 5.0 0.5 5.1 5 0 0 5 5 4 0 Tetratricopeptide repeat Arylsulfotran_2 PF14269.6 ORY03048.1 - 1.3e-53 182.3 1.1 2.2e-53 181.6 1.1 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 ORY03048.1 - 1.3e-16 60.5 1.9 6.5e-16 58.2 0.8 2.3 2 1 0 2 2 2 1 Arylsulfotransferase (ASST) PQQ PF01011.21 ORY03048.1 - 0.087 12.8 1.2 2.5 8.2 0.1 3.3 3 0 0 3 3 3 0 PQQ enzyme repeat HET PF06985.11 ORY03049.1 - 2.1e-25 89.8 0.2 4.3e-25 88.8 0.2 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF3328 PF11807.8 ORY03051.1 - 7.7e-36 123.9 0.5 8.8e-36 123.7 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) FERM_F1 PF18379.1 ORY03051.1 - 0.0023 17.9 0.0 0.0035 17.3 0.0 1.3 1 0 0 1 1 1 1 FERM F1 ubiquitin-like domain Methyltransf_23 PF13489.6 ORY03053.1 - 5.7e-06 26.3 0.0 1.1e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY03053.1 - 2.9e-05 24.7 0.0 6.4e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY03053.1 - 0.003 18.2 0.0 0.0064 17.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.18 ORY03053.1 - 0.012 15.0 0.0 0.019 14.5 0.0 1.2 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain RNase_H PF00075.24 ORY03054.1 - 3.8e-24 85.5 0.0 6.6e-24 84.7 0.0 1.4 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.6 ORY03054.1 - 0.00037 20.3 0.0 0.0061 16.4 0.0 2.2 1 1 0 1 1 1 1 Reverse transcriptase-like DUF2288 PF10052.9 ORY03055.1 - 0.15 12.2 0.1 0.23 11.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2288) Pkinase PF00069.25 ORY03056.1 - 4.3e-74 249.2 0.0 5.9e-74 248.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY03056.1 - 8.5e-39 133.4 0.0 1.2e-38 132.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase AdenylateSensor PF16579.5 ORY03056.1 - 1.9e-18 67.0 0.0 7.9e-08 32.8 0.0 3.5 3 0 0 3 3 3 3 Adenylate sensor of SNF1-like protein kinase UBA_2 PF08587.11 ORY03056.1 - 9e-16 57.7 0.1 1.8e-15 56.7 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.6 ORY03056.1 - 1e-05 25.0 0.0 1.9e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 ORY03056.1 - 0.013 15.1 0.3 0.047 13.3 0.1 1.9 2 0 0 2 2 2 0 RIO1 family Haspin_kinase PF12330.8 ORY03056.1 - 0.016 14.1 0.1 0.028 13.4 0.1 1.4 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 ORY03056.1 - 0.058 13.3 0.2 0.24 11.3 0.1 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family YukC PF10140.9 ORY03056.1 - 0.067 12.0 0.0 0.099 11.5 0.0 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC Kdo PF06293.14 ORY03056.1 - 0.17 11.2 0.1 0.36 10.1 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RSRP PF17069.5 ORY03056.1 - 0.73 9.4 32.3 1.6 8.3 32.3 1.4 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 MFS_1 PF07690.16 ORY03058.1 - 5.9e-32 110.9 27.6 5.9e-32 110.9 27.6 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 ORY03058.1 - 0.0017 18.1 1.9 0.0036 17.0 1.9 1.6 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 Imm57 PF15596.6 ORY03058.1 - 0.084 13.2 0.0 0.15 12.4 0.0 1.3 1 0 0 1 1 1 0 Immunity protein 57 LMWPc PF01451.21 ORY03060.1 - 1.2e-32 113.3 0.0 1.7e-32 112.7 0.0 1.3 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase DUF3586 PF12131.8 ORY03060.1 - 1.1 9.5 4.7 1.1 9.5 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3586) Chitin_synth_1 PF01644.17 ORY03061.1 - 1.9e-75 252.3 0.8 3.1e-75 251.6 0.8 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 ORY03061.1 - 2.3e-30 104.4 0.0 4.3e-30 103.5 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 ORY03061.1 - 4.6e-21 75.0 5.4 3.4e-17 62.3 0.0 2.4 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 ORY03061.1 - 9.4e-08 32.2 6.4 9.4e-08 32.2 6.4 2.5 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 ORY03061.1 - 0.0083 16.0 0.0 0.023 14.6 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase like family 2 GCP_C_terminal PF04130.13 ORY03062.1 - 6e-98 328.1 0.1 2.5e-97 326.1 0.0 1.9 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 ORY03062.1 - 1.3e-81 274.6 0.0 5.1e-81 272.7 0.0 2.0 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal tRNA-synt_1b PF00579.25 ORY03064.1 - 5.8e-22 78.4 0.0 8.7e-22 77.8 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) PRELI PF04707.14 ORY03065.1 - 3.9e-21 75.5 0.0 1e-18 67.6 0.0 2.2 2 0 0 2 2 2 2 PRELI-like family Ribosomal_60s PF00428.19 ORY03065.1 - 1.2 9.8 4.0 22 5.7 3.7 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein Y_phosphatase PF00102.27 ORY03066.1 - 0.0053 16.4 0.0 0.0076 15.8 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Zn_clus PF00172.18 ORY03067.1 - 1.3e-09 38.0 10.2 2e-09 37.4 10.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ORY03068.1 - 1.6e-15 56.9 2.4 4.5e-15 55.4 2.4 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain DNA_pol_A_exo1 PF01612.20 ORY03126.1 - 5e-12 45.9 0.0 7.7e-12 45.3 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease Mid2 PF04478.12 ORY03127.1 - 0.012 15.4 0.1 0.023 14.5 0.1 1.5 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Macoilin PF09726.9 ORY03127.1 - 0.43 9.1 2.3 0.52 8.8 2.3 1.1 1 0 0 1 1 1 0 Macoilin family DUF4267 PF14087.6 ORY03128.1 - 2.6e-17 62.9 1.1 3e-17 62.7 1.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) Ank_4 PF13637.6 ORY03130.1 - 2.4e-22 79.0 0.4 1.4e-05 25.6 0.0 6.4 5 2 1 6 6 6 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 ORY03130.1 - 2.9e-22 79.1 0.0 3.2e-09 37.3 0.0 4.6 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ORY03130.1 - 3.2e-21 73.1 0.7 0.00011 22.4 0.0 7.5 6 2 1 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 ORY03130.1 - 9.2e-19 67.3 2.9 4e-07 30.2 0.0 6.7 6 2 2 8 8 8 2 Ankyrin repeats (many copies) Ank PF00023.30 ORY03130.1 - 3e-11 43.2 3.1 0.12 12.9 0.0 6.4 7 1 1 8 8 8 4 Ankyrin repeat SAMP PF05924.11 ORY03130.1 - 0.11 11.8 0.1 0.3 10.4 0.1 1.8 1 0 0 1 1 1 0 SAMP Motif SIR2 PF02146.17 ORY03131.1 - 1.4e-53 181.4 0.0 2.6e-53 180.6 0.0 1.5 1 0 0 1 1 1 1 Sir2 family Glyco_hydro_30 PF02055.16 ORY03134.1 - 7.6e-10 38.3 0.2 1.1e-09 37.7 0.2 1.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_30C PF17189.4 ORY03134.1 - 1.8e-08 34.5 0.2 4.1e-08 33.3 0.2 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain Glyco_hydro_59 PF02057.15 ORY03134.1 - 2.7e-08 33.4 0.1 3.9e-08 32.9 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 Glyco_hydr_30_2 PF14587.6 ORY03134.1 - 0.0026 17.4 1.5 0.01 15.5 0.0 2.1 1 1 0 2 2 2 1 O-Glycosyl hydrolase family 30 dCMP_cyt_deam_1 PF00383.23 ORY03135.1 - 2.6e-26 91.4 1.8 3.6e-26 91.0 1.8 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 ORY03135.1 - 4.9e-10 39.3 0.2 8.1e-10 38.6 0.2 1.3 1 0 0 1 1 1 1 MafB19-like deaminase ATG7_N PF16420.5 ORY03136.1 - 1.8e-112 375.9 0.0 2.2e-112 375.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus ThiF PF00899.21 ORY03136.1 - 1.5e-38 132.5 0.0 2.4e-38 131.9 0.0 1.2 1 0 0 1 1 1 1 ThiF family DUF3696 PF12476.8 ORY03136.1 - 0.11 12.9 0.1 0.45 11.0 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3696) p450 PF00067.22 ORY03138.1 - 4.8e-56 190.4 0.0 6.9e-56 189.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 KilA-N PF04383.13 ORY03142.1 - 1e-05 25.3 0.3 0.00041 20.2 0.0 2.7 2 1 0 2 2 2 1 KilA-N domain Ank_2 PF12796.7 ORY03143.1 - 3.4e-09 37.2 0.0 0.0018 18.9 0.0 2.7 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ORY03143.1 - 5.2e-08 32.6 0.2 3.8 8.4 0.0 4.8 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 ORY03143.1 - 4.1e-05 23.8 0.1 3.7 8.0 0.0 4.4 3 1 1 4 4 4 2 Ankyrin repeats (many copies) MFS_1 PF07690.16 ORY03145.1 - 7.1e-30 104.1 44.2 7.1e-30 104.1 44.2 1.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Prenyltrans PF00432.21 ORY03146.1 - 0.0049 16.6 0.2 6.6 6.6 0.0 3.3 3 0 0 3 3 3 2 Prenyltransferase and squalene oxidase repeat Sulfotransfer_4 PF17784.1 ORY03147.1 - 5.9e-58 196.2 0.0 6.8e-58 196.0 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 ORY03147.1 - 5e-05 23.8 0.0 0.00013 22.4 0.0 1.9 1 1 1 2 2 2 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 ORY03147.1 - 0.14 11.6 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 Sulfotransferase domain PspB PF06667.12 ORY03148.1 - 0.083 13.0 0.1 0.26 11.4 0.1 1.9 1 0 0 1 1 1 0 Phage shock protein B DUF2140 PF09911.9 ORY03148.1 - 0.2 11.2 0.6 0.55 9.8 0.6 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2140) Keratin_assoc PF09775.9 ORY03148.1 - 9.3 5.9 11.9 0.14 11.8 0.4 2.7 3 0 0 3 3 3 0 Keratinocyte-associated protein 2 p450 PF00067.22 ORY03149.1 - 2.3e-62 211.3 0.0 2.9e-62 210.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SRP72 PF08492.12 ORY03149.1 - 0.026 14.9 0.3 0.053 14.0 0.3 1.5 1 0 0 1 1 1 0 SRP72 RNA-binding domain DUF4635 PF15466.6 ORY03151.1 - 0.12 11.9 0.5 0.42 10.1 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4635) CH PF00307.31 ORY03152.1 - 2.2e-74 246.6 0.1 1.5e-20 73.4 0.0 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.6 ORY03152.1 - 2.6e-06 27.8 1.3 1.6e-05 25.3 0.4 2.5 2 0 0 2 2 2 1 EF-hand domain pair CAMSAP_CH PF11971.8 ORY03152.1 - 5.7e-05 22.9 0.0 0.061 13.2 0.0 3.4 3 0 0 3 3 3 1 CAMSAP CH domain EF-hand_6 PF13405.6 ORY03152.1 - 0.00037 20.2 0.4 0.019 14.9 0.1 2.9 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 ORY03152.1 - 0.00067 19.0 0.5 0.51 10.0 0.0 3.5 3 0 0 3 3 3 1 EF hand HET PF06985.11 ORY03155.1 - 2.9e-28 99.1 0.0 4.9e-28 98.3 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.7 ORY03156.1 - 1.4e-21 76.9 0.0 1e-14 54.9 0.2 3.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ORY03156.1 - 2.4e-14 53.2 0.3 6.1e-11 42.4 0.1 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 ORY03156.1 - 4.5e-14 52.6 0.1 2.8e-07 31.0 0.0 3.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 ORY03156.1 - 1.8e-12 47.1 2.9 5.4e-08 32.9 0.3 4.5 4 0 0 4 4 3 2 Ankyrin repeat Ank_3 PF13606.6 ORY03156.1 - 7.2e-12 44.4 0.1 0.0031 17.9 0.1 5.0 4 0 0 4 4 4 2 Ankyrin repeat NACHT PF05729.12 ORY03156.1 - 2.5e-09 37.3 0.1 7e-09 35.8 0.1 1.8 1 0 0 1 1 1 1 NACHT domain Helo_like_N PF17111.5 ORY03156.1 - 6.1e-07 29.0 2.1 2.6e-06 27.0 2.1 2.2 1 1 0 1 1 1 1 Fungal N-terminal domain of STAND proteins AAA_16 PF13191.6 ORY03156.1 - 2e-05 25.1 0.1 7.5e-05 23.2 0.0 2.0 2 0 0 2 2 1 1 AAA ATPase domain AAA_22 PF13401.6 ORY03156.1 - 4.4e-05 23.8 0.7 0.00086 19.6 0.0 3.2 3 1 0 3 3 3 1 AAA domain NB-ARC PF00931.22 ORY03156.1 - 0.0025 17.0 0.0 0.013 14.7 0.0 2.0 1 1 0 1 1 1 1 NB-ARC domain AAA PF00004.29 ORY03156.1 - 0.074 13.5 0.0 0.33 11.4 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 ORY03156.1 - 0.13 12.0 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain Baculo_PEP_C PF04513.12 ORY03156.1 - 0.2 11.7 5.5 2.6 8.1 0.4 3.2 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus 4HBT PF03061.22 ORY03157.1 - 3.4e-10 40.1 0.3 4.8e-10 39.7 0.3 1.2 1 0 0 1 1 1 1 Thioesterase superfamily PXA PF02194.15 ORY03158.1 - 2.8e-32 112.2 0.0 2.8e-32 112.2 0.0 2.1 3 0 0 3 3 3 1 PXA domain Nexin_C PF08628.12 ORY03158.1 - 5.8e-20 72.0 0.0 1.4e-19 70.7 0.0 1.7 1 0 0 1 1 1 1 Sorting nexin C terminal PX PF00787.24 ORY03158.1 - 2.9e-08 33.7 0.0 1.3e-07 31.6 0.0 2.1 2 0 0 2 2 2 1 PX domain FliJ PF02050.16 ORY03158.1 - 0.79 10.0 10.5 2.3 8.5 10.5 1.7 1 1 0 1 1 1 0 Flagellar FliJ protein Prominin PF05478.11 ORY03159.1 - 0.00023 19.3 7.1 0.00023 19.3 7.1 6.6 5 2 1 6 6 6 1 Prominin DUF3502 PF12010.8 ORY03159.1 - 0.02 15.6 0.6 1.3 9.7 0.3 4.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3502) TAFH PF07531.14 ORY03159.1 - 0.11 12.7 0.1 6.6 6.9 0.0 3.5 3 0 0 3 3 3 0 NHR1 homology to TAF Hpt PF01627.23 ORY03159.1 - 2.4 8.5 14.4 28 5.0 3.2 6.3 3 2 2 5 5 5 0 Hpt domain RPN6_N PF18055.1 ORY03160.1 - 1.6e-45 154.3 1.7 2.4e-45 153.6 0.6 1.9 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN6 N-terminal domain TPR_MalT PF17874.1 ORY03160.1 - 2.9e-07 30.2 1.8 0.00016 21.2 1.8 2.9 1 1 2 3 3 3 2 MalT-like TPR region TPR_14 PF13428.6 ORY03160.1 - 0.0021 18.7 1.5 1.3 10.0 0.0 4.3 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 ORY03160.1 - 0.0094 16.4 2.4 4.1 8.0 0.0 4.3 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 ORY03160.1 - 0.01 16.1 7.1 0.67 10.3 0.6 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat Prefoldin_2 PF01920.20 ORY03160.1 - 0.05 13.6 0.9 0.15 12.0 0.4 2.1 2 0 0 2 2 2 0 Prefoldin subunit TPR_7 PF13176.6 ORY03160.1 - 0.075 13.1 0.6 12 6.2 0.1 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 ORY03160.1 - 0.12 13.0 2.5 1.4 9.7 0.0 3.8 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 ORY03160.1 - 0.27 11.4 2.5 12 6.3 0.1 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat MDM10 PF12519.8 ORY03204.1 - 1.7e-150 502.0 4.0 2.3e-132 442.2 1.6 2.0 1 1 1 2 2 2 2 Mitochondrial distribution and morphology protein 10 Porin_3 PF01459.22 ORY03204.1 - 2.8e-07 30.3 0.0 0.011 15.2 0.0 3.1 3 1 0 3 3 3 2 Eukaryotic porin Homeodomain PF00046.29 ORY03205.1 - 1.8e-19 69.3 4.2 3.5e-19 68.4 4.2 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 ORY03205.1 - 0.0017 18.2 0.6 0.004 17.0 0.6 1.6 1 0 0 1 1 1 1 Homeobox KN domain Aminotran_1_2 PF00155.21 ORY03206.1 - 1.8e-61 208.3 0.0 2.6e-61 207.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II TPR_22 PF18833.1 ORY03207.1 - 0.056 13.6 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat B-block_TFIIIC PF04182.12 ORY03208.1 - 5.5e-19 68.1 0.0 1.1e-18 67.1 0.0 1.6 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC AT_hook PF02178.19 ORY03208.1 - 1 9.5 14.8 3.3 7.9 5.6 3.4 2 0 0 2 2 2 0 AT hook motif CSRNP_N PF16019.5 ORY03209.1 - 2.5 8.0 4.7 3.8 7.4 4.7 1.2 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus GDPD_2 PF13653.6 ORY03211.1 - 0.0039 17.6 0.4 0.008 16.6 0.4 1.6 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GATase_4 PF13230.6 ORY03212.1 - 1e-15 57.4 0.0 4.1e-14 52.1 0.0 2.2 2 0 0 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.6 ORY03212.1 - 1.2e-09 38.5 0.0 2.1e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain Arm PF00514.23 ORY03213.1 - 2.9e-98 319.3 14.3 8.9e-14 51.0 0.2 8.4 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat IBB PF01749.20 ORY03213.1 - 4e-26 91.3 1.6 4e-26 91.3 1.6 2.0 2 0 0 2 2 2 1 Importin beta binding domain Arm_3 PF16186.5 ORY03213.1 - 2.2e-23 81.5 1.7 5.2e-23 80.4 1.7 1.7 1 0 0 1 1 1 1 Atypical Arm repeat HEAT_EZ PF13513.6 ORY03213.1 - 7.1e-22 77.5 8.5 1.8e-08 34.7 0.1 6.7 6 1 1 7 7 7 5 HEAT-like repeat HEAT_2 PF13646.6 ORY03213.1 - 2.8e-20 72.5 2.7 2.4e-09 37.5 0.1 5.7 2 1 3 5 5 5 3 HEAT repeats HEAT PF02985.22 ORY03213.1 - 7.6e-19 66.2 2.2 1.8e-05 24.6 0.0 7.3 8 0 0 8 8 8 4 HEAT repeat Arm_2 PF04826.13 ORY03213.1 - 1.3e-08 34.6 0.0 0.086 12.3 0.0 4.1 2 1 2 4 4 4 3 Armadillo-like Adaptin_N PF01602.20 ORY03213.1 - 2.7e-06 26.2 0.0 7.7e-05 21.4 0.0 2.5 1 1 2 3 3 3 1 Adaptin N terminal region V-ATPase_H_C PF11698.8 ORY03213.1 - 4.4e-05 23.6 0.0 1.6 8.9 0.0 4.7 3 2 2 5 5 5 2 V-ATPase subunit H Cnd1 PF12717.7 ORY03213.1 - 0.00049 20.2 0.0 0.78 9.8 0.0 3.2 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_PBS PF03130.16 ORY03213.1 - 0.0043 17.6 6.5 0.66 10.8 0.3 5.1 5 0 0 5 5 5 1 PBS lyase HEAT-like repeat NopRA1 PF16201.5 ORY03213.1 - 0.0062 16.1 0.0 11 5.6 0.0 3.8 1 1 2 4 4 4 1 Nucleolar pre-ribosomal-associated protein 1 RICTOR_V PF14668.6 ORY03213.1 - 0.029 14.6 6.2 2.4 8.4 0.1 4.9 3 2 3 6 6 6 0 Rapamycin-insensitive companion of mTOR, domain 5 Glycos_trans_3N PF02885.17 ORY03213.1 - 0.034 14.0 0.0 33 4.4 0.0 3.5 3 0 0 3 3 3 0 Glycosyl transferase family, helical bundle domain POT1PC PF16686.5 ORY03214.1 - 3.5e-27 95.2 0.0 1.7e-26 93.0 0.0 2.1 1 1 0 1 1 1 1 ssDNA-binding domain of telomere protection protein POT1 PF02765.17 ORY03214.1 - 2.8e-05 24.0 0.0 5.7e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 KdpC PF02669.15 ORY03214.1 - 0.16 11.8 0.2 0.29 11.0 0.2 1.3 1 0 0 1 1 1 0 K+-transporting ATPase, c chain AMP-binding PF00501.28 ORY03219.1 - 6.4e-39 133.7 0.0 1e-38 133.1 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 ORY03219.1 - 7.2e-10 38.6 0.2 7.2e-10 38.6 0.2 2.8 3 0 0 3 3 3 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 ORY03219.1 - 0.0007 20.5 1.2 0.0018 19.2 0.2 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain IBR PF01485.21 ORY03220.1 - 2.9e-13 49.8 29.5 3.5e-07 30.3 7.7 3.6 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain zf_CCCH_4 PF18345.1 ORY03220.1 - 1.1e-08 34.9 17.9 0.00035 20.5 1.3 3.9 3 0 0 3 3 3 3 Zinc finger domain Torus PF16131.5 ORY03220.1 - 3.4e-08 34.1 7.2 0.0013 19.4 0.2 3.2 2 1 1 3 3 3 2 Torus domain zf-CCCH PF00642.24 ORY03220.1 - 5.9e-08 32.4 17.5 4.1e-05 23.4 1.0 4.0 4 0 0 4 4 4 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.22 ORY03220.1 - 9.2e-06 25.4 0.0 0.3 10.9 0.0 3.8 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH_3 PF15663.5 ORY03220.1 - 0.00015 21.9 3.8 0.26 11.5 0.4 3.3 2 1 0 2 2 2 2 Zinc-finger containing family zf-CCCH_4 PF18044.1 ORY03220.1 - 0.0027 17.5 0.3 0.0027 17.5 0.3 4.3 5 0 0 5 5 5 2 CCCH-type zinc finger zf-RING_5 PF14634.6 ORY03220.1 - 0.0041 17.0 6.2 0.0041 17.0 6.2 3.6 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4 PF00097.25 ORY03220.1 - 0.0077 16.1 6.6 0.0077 16.1 6.6 4.0 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) Acetyltransf_7 PF13508.7 ORY03221.1 - 0.00072 19.9 0.0 0.002 18.5 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ORY03221.1 - 0.0013 18.7 0.0 0.0025 17.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORY03221.1 - 0.0015 18.7 0.0 0.0028 17.9 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 ORY03221.1 - 0.011 15.8 0.0 3.2 7.8 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Cu-oxidase_2 PF07731.14 ORY03222.1 - 4.3e-20 71.8 0.9 2.5e-17 62.9 0.5 2.5 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 ORY03222.1 - 6.6e-19 68.1 0.1 1.6e-18 66.8 0.1 1.6 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase PF00394.22 ORY03222.1 - 3.7e-05 23.9 0.0 0.00067 19.8 0.0 2.5 2 0 0 2 2 2 1 Multicopper oxidase Glyco_hydro_2 PF00703.21 ORY03223.1 - 0.038 14.7 0.8 0.13 12.9 0.8 1.9 1 0 0 1 1 1 0 Glycosyl hydrolases family 2 DUF1102 PF06510.11 ORY03223.1 - 0.07 13.3 0.1 0.18 12.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1102) CEL_III_C PF18054.1 ORY03223.1 - 0.23 11.5 1.4 0.54 10.3 1.4 1.5 1 0 0 1 1 1 0 CEL-III C-terminal EGF_3 PF12947.7 ORY03224.1 - 0.011 15.9 1.5 0.045 13.9 1.5 2.1 1 0 0 1 1 1 0 EGF domain FAIM1 PF06905.13 ORY03226.1 - 0.12 12.1 0.2 0.18 11.5 0.2 1.2 1 0 0 1 1 1 0 Fas apoptotic inhibitory molecule (FAIM1) A_deaminase PF00962.22 ORY03229.1 - 1e-29 103.9 0.0 1.3e-29 103.6 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase WD40 PF00400.32 ORY03230.1 - 2.3e-36 123.2 18.8 1.5e-05 25.6 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY03230.1 - 1.1e-16 60.8 0.0 0.00028 21.1 0.1 5.1 1 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ORY03230.1 - 7.8e-05 22.6 0.0 0.039 13.8 0.0 2.7 1 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 ORY03230.1 - 0.0011 18.4 0.0 0.034 13.5 0.0 2.8 2 1 1 3 3 3 1 WD40-like domain Cytochrom_D1 PF02239.16 ORY03230.1 - 0.097 11.2 0.1 0.19 10.2 0.0 1.5 2 0 0 2 2 2 0 Cytochrome D1 heme domain Atg14 PF10186.9 ORY03230.1 - 0.33 10.0 1.6 0.48 9.5 1.6 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Phosducin PF02114.16 ORY03233.1 - 1.5e-09 37.2 0.0 2.1e-06 26.9 0.0 2.2 1 1 1 2 2 2 2 Phosducin SIP1 PF04938.12 ORY03233.1 - 0.092 12.4 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Survival motor neuron (SMN) interacting protein 1 (SIP1) FA_desaturase PF00487.24 ORY03236.1 - 3.2e-11 43.5 21.2 5.8e-11 42.7 21.2 1.4 1 0 0 1 1 1 1 Fatty acid desaturase OAD_gamma PF04277.13 ORY03237.1 - 0.024 15.2 0.0 0.035 14.7 0.0 1.2 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain HET PF06985.11 ORY03239.1 - 4.1e-13 49.9 0.2 4.1e-13 49.9 0.2 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) GDA1_CD39 PF01150.17 ORY03240.1 - 1.7e-102 343.2 0.0 2.2e-102 342.9 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.16 ORY03240.1 - 0.02 14.4 0.0 0.031 13.7 0.0 1.2 1 0 0 1 1 1 0 Ppx/GppA phosphatase family Flavodoxin_5 PF12724.7 ORY03298.1 - 3.7e-22 79.1 0.0 5.2e-22 78.7 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin domain Flavodoxin_1 PF00258.25 ORY03298.1 - 3.3e-05 24.1 0.0 5.6e-05 23.4 0.0 1.6 1 1 0 1 1 1 1 Flavodoxin Flavodoxin_3 PF12641.7 ORY03298.1 - 0.011 15.4 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 0 Flavodoxin domain GCP_N_terminal PF17681.1 ORY03299.1 - 5.8e-41 141.1 0.2 1.7e-40 139.6 0.0 1.8 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 ORY03299.1 - 2.2e-27 96.4 0.4 5.6e-27 95.0 0.1 1.9 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal GCP5-Mod21 PF14609.6 ORY03299.1 - 2.8e-05 22.7 0.6 0.04 12.3 0.0 2.9 3 0 0 3 3 3 2 gamma-Tubulin ring complex non-core subunit mod21 Glyco_transf_15 PF01793.16 ORY03300.1 - 2.5e-113 378.6 9.9 2.9e-113 378.4 9.9 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase COX5A PF02284.16 ORY03301.1 - 9.5e-40 134.8 0.2 1.2e-39 134.4 0.2 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va PHO4 PF01384.20 ORY03302.1 - 8e-110 367.0 8.9 9.2e-110 366.8 8.9 1.0 1 0 0 1 1 1 1 Phosphate transporter family Caveolin PF01146.17 ORY03302.1 - 0.02 14.8 0.1 0.077 13.0 0.1 1.9 1 0 0 1 1 1 0 Caveolin Phage_Coat_B PF05356.11 ORY03302.1 - 0.095 12.6 0.5 0.5 10.3 0.5 2.3 1 0 0 1 1 1 0 Phage Coat protein B MIG-14_Wnt-bd PF06664.12 ORY03302.1 - 4.5 6.4 6.5 4.7 6.4 0.1 3.0 3 0 0 3 3 3 0 Wnt-binding factor required for Wnt secretion DUF373 PF04123.13 ORY03302.1 - 9.7 5.5 14.4 0.56 9.6 2.3 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF373) GATase_5 PF13507.6 ORY03303.1 - 4.5e-101 337.3 0.0 8.3e-101 336.5 0.0 1.5 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 ORY03303.1 - 1.3e-38 132.6 0.3 3.2e-25 89.1 0.0 2.4 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain FGAR-AT_N PF18076.1 ORY03303.1 - 7.8e-32 109.7 0.0 1.4e-31 108.8 0.0 1.5 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase N-terminal FGAR-AT_linker PF18072.1 ORY03303.1 - 4.7e-21 75.1 0.5 1.6e-20 73.3 0.1 2.2 2 0 0 2 2 2 1 Formylglycinamide ribonucleotide amidotransferase linker domain B56 PF01603.20 ORY03304.1 - 6.9e-192 638.0 4.7 8.2e-192 637.7 4.7 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Sec7_N PF12783.7 ORY03304.1 - 0.00059 19.8 1.3 0.3 11.0 0.0 2.4 2 0 0 2 2 2 2 Guanine nucleotide exchange factor in Golgi transport N-terminal SOG2 PF10428.9 ORY03304.1 - 2.1 7.4 7.0 18 4.4 0.0 2.2 2 0 0 2 2 2 0 RAM signalling pathway protein ELO PF01151.18 ORY03305.1 - 1.4e-61 208.2 22.0 1.6e-61 208.0 22.0 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Kelch_5 PF13854.6 ORY03305.1 - 0.031 14.3 0.0 0.1 12.6 0.0 2.0 1 0 0 1 1 1 0 Kelch motif Tau95_N PF17682.1 ORY03306.1 - 6.4e-31 107.2 0.0 1.5e-30 106.0 0.0 1.7 1 0 0 1 1 1 1 Tau95 Triple barrel domain Tau95 PF09734.9 ORY03306.1 - 2.6e-28 99.6 0.2 5.1e-28 98.6 0.2 1.5 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Hox9_act PF04617.13 ORY03306.1 - 0.074 13.8 0.1 0.19 12.5 0.1 1.6 1 0 0 1 1 1 0 Hox9 activation region SDA1 PF05285.12 ORY03306.1 - 5 6.4 25.3 7.4 5.9 25.3 1.2 1 0 0 1 1 1 0 SDA1 TFIIA PF03153.13 ORY03306.1 - 5.8 6.8 18.9 12 5.8 18.9 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RNA_pol_3_Rpc31 PF11705.8 ORY03306.1 - 6.4 7.0 23.0 20 5.3 23.0 2.0 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 FAT PF02259.23 ORY03307.1 - 3.8e-72 243.4 8.0 9.6e-72 242.1 8.0 1.8 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.27 ORY03307.1 - 5.4e-35 121.4 0.0 1.7e-34 119.8 0.0 2.0 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 ORY03307.1 - 1.5e-06 27.9 0.2 3.9e-06 26.6 0.2 1.8 1 0 0 1 1 1 1 FATC domain Thymidylat_synt PF00303.19 ORY03307.1 - 0.0088 15.2 0.4 0.036 13.2 0.3 1.9 2 0 0 2 2 2 1 Thymidylate synthase Ank_2 PF12796.7 ORY03308.1 - 2.2e-09 37.7 0.1 4.2e-09 36.9 0.1 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY03308.1 - 9.4e-09 35.7 0.1 1e-07 32.3 0.2 2.4 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 ORY03308.1 - 2.1e-07 31.1 0.0 0.001 19.4 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 ORY03308.1 - 2.6e-05 24.3 0.1 0.07 13.7 0.0 2.8 2 1 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 ORY03308.1 - 0.00047 20.4 0.3 0.018 15.4 0.1 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) p450 PF00067.22 ORY03309.1 - 8.9e-15 54.4 0.0 1.1e-14 54.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_61 PF03443.14 ORY03311.1 - 1.3e-49 168.9 0.1 1.6e-49 168.6 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Transglut_core PF01841.19 ORY03312.1 - 1.6e-12 47.8 0.1 4.2e-12 46.5 0.1 1.7 1 0 0 1 1 1 1 Transglutaminase-like superfamily SH3_2 PF07653.17 ORY03312.1 - 1.6e-08 34.1 0.1 3.8e-08 32.9 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 ORY03312.1 - 2.2e-07 30.4 0.1 4.9e-07 29.2 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 ORY03312.1 - 0.00079 19.2 0.1 0.002 18.0 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain tRNA-synt_1c PF00749.21 ORY03313.1 - 2.4e-106 355.2 0.0 3.2e-106 354.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 ORY03313.1 - 5.8e-34 117.5 0.1 1e-33 116.7 0.1 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_3 PF14497.6 ORY03313.1 - 0.042 14.1 0.0 0.38 11.0 0.0 2.3 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 ORY03313.1 - 0.083 13.1 0.0 0.19 12.0 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain UQ_con PF00179.26 ORY03314.1 - 5.4e-51 171.9 0.0 6.1e-51 171.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 ORY03314.1 - 0.19 11.4 0.2 0.52 10.0 0.2 1.7 1 1 0 1 1 1 0 Prokaryotic E2 family B Oxidored_molyb PF00174.19 ORY03315.1 - 3.2e-59 199.4 0.0 5.9e-59 198.5 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 ORY03315.1 - 1.7e-26 92.9 0.8 2.9e-26 92.1 0.8 1.3 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain bMG3 PF11974.8 ORY03315.1 - 0.06 13.4 0.0 0.33 11.0 0.0 2.0 2 0 0 2 2 2 0 Bacterial alpha-2-macroglobulin MG3 domain Scramblase PF03803.15 ORY03317.1 - 1.3e-53 181.5 0.0 8e-30 103.8 0.0 2.9 1 1 1 2 2 2 2 Scramblase Caleosin PF05042.13 ORY03318.1 - 5.1e-79 264.1 0.4 1.1e-78 263.1 0.7 1.3 2 0 0 2 2 2 1 Caleosin related protein tRNA_int_endo PF01974.17 ORY03319.1 - 8.1e-18 64.3 0.1 1.9e-17 63.1 0.1 1.6 1 1 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.14 ORY03319.1 - 1e-05 25.1 0.0 0.0049 16.5 0.0 2.4 2 0 0 2 2 2 2 tRNA intron endonuclease, N-terminal domain Apis_Csd PF11671.8 ORY03320.1 - 2 8.4 8.9 4.5 7.3 8.9 1.6 1 0 0 1 1 1 0 Complementary sex determiner protein Borrelia_P83 PF05262.11 ORY03322.1 - 2.1 6.8 5.0 3.9 5.9 5.0 1.4 1 0 0 1 1 1 0 Borrelia P83/100 protein Alpha-L-AF_C PF06964.12 ORY03323.1 - 9.3e-27 94.2 0.1 2.2e-26 93.0 0.0 1.6 2 0 0 2 2 2 1 Alpha-L-arabinofuranosidase C-terminal domain phage_tail_N PF08400.10 ORY03323.1 - 0.076 13.0 0.1 0.23 11.4 0.0 1.8 2 0 0 2 2 2 0 Prophage tail fibre N-terminal Fungal_trans PF04082.18 ORY03324.1 - 6.6e-33 113.9 0.1 1.1e-32 113.2 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY03324.1 - 1.3e-06 28.4 9.0 1.3e-06 28.4 9.0 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NAD_binding_4 PF07993.12 ORY03325.1 - 9.8e-25 87.2 0.0 2.6e-24 85.8 0.0 1.6 2 0 0 2 2 2 1 Male sterility protein AMP-binding PF00501.28 ORY03325.1 - 1.4e-15 56.9 0.0 6.3e-15 54.7 0.0 1.8 1 1 1 2 2 2 1 AMP-binding enzyme Epimerase PF01370.21 ORY03325.1 - 1e-05 25.1 0.0 2.1e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family HET PF06985.11 ORY03326.1 - 1.4e-20 74.2 0.1 1.6e-20 74.0 0.1 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.16 ORY03329.1 - 1.6e-32 112.9 32.5 1.6e-32 112.9 32.5 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 ORY03329.1 - 2.3e-05 23.1 6.0 0.00064 18.3 2.3 2.3 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Glyco_hydro_10 PF00331.20 ORY03330.1 - 4.2e-103 344.8 1.2 5e-103 344.6 1.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Anoctamin PF04547.12 ORY03331.1 - 2.3e-31 109.1 0.3 1.2e-13 50.7 0.1 3.0 2 1 1 3 3 3 3 Calcium-activated chloride channel DUF5027 PF16430.5 ORY03332.1 - 0.17 11.6 0.0 0.22 11.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5027) DUF2293 PF10056.9 ORY03334.1 - 1.2e-32 112.0 0.9 4e-32 110.3 0.1 1.9 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2293) DUF2122 PF09895.9 ORY03334.1 - 0.019 15.4 0.0 0.035 14.5 0.0 1.4 1 1 0 1 1 1 0 RecB-family nuclease (DUF2122) DUF5598 PF18127.1 ORY03334.1 - 0.1 13.0 0.0 0.17 12.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5598) NmrA PF05368.13 ORY03335.1 - 4e-14 52.7 0.0 5.6e-14 52.3 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ORY03335.1 - 8.7e-13 48.6 0.1 1.7e-12 47.6 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 ORY03335.1 - 0.00017 21.2 0.0 0.00028 20.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 ORY03335.1 - 0.00043 20.7 0.1 0.00077 19.9 0.1 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 ORY03335.1 - 0.004 18.0 0.0 0.0071 17.2 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold CoA_binding PF02629.19 ORY03335.1 - 0.0091 16.7 0.5 0.025 15.3 0.3 1.8 2 0 0 2 2 2 1 CoA binding domain Shikimate_DH PF01488.20 ORY03335.1 - 0.03 14.4 0.0 0.052 13.6 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DapB_N PF01113.20 ORY03335.1 - 0.1 12.7 0.1 0.24 11.5 0.1 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus DUF166 PF02593.14 ORY03335.1 - 0.13 11.7 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function 3Beta_HSD PF01073.19 ORY03335.1 - 0.16 10.9 0.1 0.28 10.2 0.1 1.5 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_2 PF00891.18 ORY03336.1 - 3.5e-17 62.4 0.0 6.1e-17 61.6 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain HTH_27 PF13463.6 ORY03336.1 - 0.0053 17.2 0.0 0.017 15.6 0.0 1.8 1 0 0 1 1 1 1 Winged helix DNA-binding domain HDA2-3 PF11496.8 ORY03337.1 - 1e-10 41.3 2.3 0.00022 20.5 0.0 3.0 3 0 0 3 3 3 2 Class II histone deacetylase complex subunits 2 and 3 Seadorna_VP6 PF07407.11 ORY03337.1 - 0.44 9.5 2.7 0.85 8.5 2.7 1.4 1 0 0 1 1 1 0 Seadornavirus VP6 protein FH2 PF02181.23 ORY03337.1 - 3.5 6.7 24.0 0.091 11.9 2.7 3.2 2 1 1 3 3 3 0 Formin Homology 2 Domain HET PF06985.11 ORY03404.1 - 1e-28 100.5 0.3 3.9e-28 98.6 0.3 1.8 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) AMP-binding PF00501.28 ORY03405.1 - 2.4e-11 42.9 0.0 2.7e-11 42.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Sugar_tr PF00083.24 ORY03406.1 - 1.2e-31 110.1 7.0 1.3e-31 109.9 7.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY03406.1 - 6.6e-14 51.6 3.2 8.7e-14 51.2 3.2 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 ORY03406.1 - 3.1e-06 25.8 0.5 3.7e-06 25.5 0.5 1.1 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family DUF2938 PF11158.8 ORY03406.1 - 0.064 12.7 1.5 0.096 12.2 0.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2938) ECF_trnsprt PF12822.7 ORY03406.1 - 1.4 9.0 11.3 0.58 10.2 6.8 2.1 1 1 1 2 2 2 0 ECF transporter, substrate-specific component BTB PF00651.31 ORY03408.1 - 2.1e-07 31.2 0.0 3.5e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain IBR PF01485.21 ORY03408.1 - 4.8 7.5 8.7 0.33 11.2 3.2 1.9 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain KH_1 PF00013.29 ORY03409.1 - 9.9e-43 143.8 3.4 3.3e-18 65.3 0.2 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 ORY03409.1 - 7.3e-12 45.0 0.8 0.0047 16.7 0.2 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 ORY03409.1 - 5.3e-05 23.2 4.1 0.22 11.6 0.2 3.3 3 0 0 3 3 3 2 NusA-like KH domain KH_4 PF13083.6 ORY03409.1 - 5.4e-05 23.0 1.3 1.3 8.9 0.1 3.3 3 0 0 3 3 3 2 KH domain MOEP19 PF16005.5 ORY03409.1 - 6.2e-05 22.9 0.0 0.0078 16.2 0.0 2.9 3 0 0 3 3 3 1 KH-like RNA-binding domain DUF2362 PF10154.9 ORY03410.1 - 1.1e-05 24.6 1.7 1.5e-05 24.1 1.7 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2362) CENP-K PF11802.8 ORY03410.1 - 0.018 14.6 5.6 4.3 6.8 0.0 2.8 2 1 0 2 2 2 0 Centromere-associated protein K Fib_alpha PF08702.10 ORY03410.1 - 5.6 7.1 8.8 3.2 8.0 0.4 2.5 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Laminin_II PF06009.12 ORY03410.1 - 5.7 7.0 10.3 1.4 9.0 1.8 2.8 1 1 2 4 4 4 0 Laminin Domain II Bys1 PF04681.12 ORY03411.1 - 0.072 13.0 0.0 0.1 12.6 0.0 1.2 1 0 0 1 1 1 0 Blastomyces yeast-phase-specific protein DUF543 PF04418.12 ORY03412.1 - 0.88 9.6 5.4 0.55 10.2 0.5 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF543) CP2 PF04516.15 ORY03414.1 - 3e-81 272.1 0.0 4.6e-81 271.5 0.0 1.2 1 0 0 1 1 1 1 CP2 transcription factor AKNA PF12443.8 ORY03414.1 - 0.0097 16.5 0.2 0.033 14.9 0.2 1.9 1 0 0 1 1 1 1 AT-hook-containing transcription factor PemK_toxin PF02452.17 ORY03414.1 - 0.14 12.5 0.0 0.43 11.0 0.0 1.8 1 0 0 1 1 1 0 PemK-like, MazF-like toxin of type II toxin-antitoxin system MAM33 PF02330.16 ORY03416.1 - 4.4e-72 242.5 5.4 1.3e-71 241.0 5.4 1.6 1 1 0 1 1 1 1 Mitochondrial glycoprotein MukF_C PF17193.4 ORY03416.1 - 0.02 15.1 0.1 0.038 14.1 0.1 1.4 1 0 0 1 1 1 0 MukF C-terminal domain Ribosomal_60s PF00428.19 ORY03416.1 - 0.025 15.1 1.7 0.032 14.8 0.1 2.0 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF4166 PF13761.6 ORY03416.1 - 0.063 13.1 0.1 4.7 6.9 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4166) GED PF02212.18 ORY03416.1 - 0.073 13.2 1.3 0.15 12.2 1.3 1.5 1 0 0 1 1 1 0 Dynamin GTPase effector domain Mito_carr PF00153.27 ORY03417.1 - 3.8e-51 171.0 4.9 3.2e-21 75.1 0.1 4.0 4 0 0 4 4 4 4 Mitochondrial carrier protein Fungal_trans PF04082.18 ORY03418.1 - 8.1e-14 51.3 0.0 1.4e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY03418.1 - 4.4e-09 36.3 7.8 7.9e-09 35.5 7.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cep3 PF16846.5 ORY03418.1 - 0.044 12.3 0.0 0.066 11.7 0.0 1.2 1 0 0 1 1 1 0 Centromere DNA-binding protein complex CBF3 subunit B Chorion_1 PF01723.16 ORY03418.1 - 0.72 9.8 5.0 0.14 12.1 1.4 1.5 2 0 0 2 2 2 0 Chorion protein ABM PF03992.16 ORY03419.1 - 4.9e-08 33.0 0.0 1.8e-06 28.0 0.0 2.3 2 0 0 2 2 2 1 Antibiotic biosynthesis monooxygenase DUF1330 PF07045.11 ORY03419.1 - 7.6e-05 23.0 0.0 0.16 12.3 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF1330) Pkinase PF00069.25 ORY03420.1 - 9e-29 100.6 0.0 2.7e-27 95.8 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY03420.1 - 3.2e-13 49.6 0.0 5.3e-11 42.3 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase TSNR_N PF04705.12 ORY03420.1 - 0.066 13.3 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 Thiostrepton-resistance methylase, N terminus UQ_con PF00179.26 ORY03421.1 - 2.1e-36 124.6 0.0 2.5e-36 124.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 ORY03421.1 - 0.042 13.6 0.0 0.045 13.4 0.0 1.1 1 0 0 1 1 1 0 Prokaryotic E2 family B Pentapeptide_4 PF13599.6 ORY03424.1 - 0.0057 16.8 0.0 3 8.1 0.0 3.7 4 2 0 4 4 4 2 Pentapeptide repeats (9 copies) Glyco_hydro_92 PF07971.12 ORY03464.1 - 5.3e-153 510.3 0.1 6.6e-153 509.9 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 ORY03464.1 - 1.6e-27 97.0 0.0 2.5e-27 96.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain IBR PF01485.21 ORY03465.1 - 1.5e-10 41.1 14.7 8.9e-10 38.7 4.1 3.0 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain Dicty_CAD PF05720.12 ORY03466.1 - 0.083 12.9 0.1 0.53 10.3 0.1 2.1 2 0 0 2 2 2 0 Cell-cell adhesion domain Amidohydro_2 PF04909.14 ORY03467.1 - 8.4e-25 88.1 0.1 1.2e-24 87.7 0.1 1.2 1 0 0 1 1 1 1 Amidohydrolase PfkB PF00294.24 ORY03468.1 - 8.9e-12 44.9 0.0 9.4e-11 41.6 0.0 2.1 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Zn_clus PF00172.18 ORY03470.1 - 2.1e-09 37.3 7.9 5.5e-09 36.0 7.9 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ketoacyl-synt PF00109.26 ORY03471.1 - 3e-71 240.0 0.0 5e-71 239.2 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 ORY03471.1 - 2.6e-62 209.9 0.1 5.6e-62 208.8 0.1 1.6 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 ORY03471.1 - 4.5e-53 180.4 0.0 7e-53 179.8 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 ORY03471.1 - 1.8e-39 136.1 0.0 3.5e-39 135.2 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 ORY03471.1 - 5.2e-39 132.9 0.0 1.3e-38 131.6 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 ORY03471.1 - 1.7e-19 70.4 0.0 5.2e-19 68.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.6 ORY03471.1 - 1.8e-17 64.6 0.0 6.3e-15 56.4 0.0 3.3 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 ORY03471.1 - 9.8e-16 57.9 0.2 1.6e-14 54.0 0.1 2.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase KAsynt_C_assoc PF16197.5 ORY03471.1 - 6.2e-14 52.4 0.0 1.3e-13 51.4 0.0 1.6 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_25 PF13649.6 ORY03471.1 - 8.6e-13 48.8 0.3 2.3e-11 44.3 0.0 3.2 3 0 0 3 3 3 1 Methyltransferase domain adh_short PF00106.25 ORY03471.1 - 1.7e-12 47.2 0.8 7.4e-11 41.9 0.1 2.4 2 0 0 2 2 2 1 short chain dehydrogenase Methyltransf_23 PF13489.6 ORY03471.1 - 1.2e-11 44.7 0.0 3.3e-11 43.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY03471.1 - 4.3e-11 43.3 0.2 9.2e-10 39.0 0.0 3.2 4 0 0 4 4 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY03471.1 - 7.1e-08 32.4 0.0 3.2e-07 30.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Thiolase_N PF00108.23 ORY03471.1 - 4.3e-06 26.3 0.1 1.2e-05 24.8 0.1 1.7 1 0 0 1 1 1 1 Thiolase, N-terminal domain adh_short_C2 PF13561.6 ORY03471.1 - 2e-05 24.3 0.9 3.7e-05 23.4 0.0 1.8 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Ubie_methyltran PF01209.18 ORY03471.1 - 3e-05 23.5 0.0 6.4e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PP-binding PF00550.25 ORY03471.1 - 6.6e-05 23.2 0.1 0.00024 21.4 0.1 2.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_2 PF00891.18 ORY03471.1 - 0.0038 16.6 0.0 0.01 15.1 0.0 1.7 1 0 0 1 1 1 1 O-methyltransferase domain 3Beta_HSD PF01073.19 ORY03471.1 - 0.0067 15.5 0.0 0.013 14.6 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 ORY03471.1 - 0.012 14.7 0.0 0.021 14.0 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Methyltransf_16 PF10294.9 ORY03471.1 - 0.022 14.5 0.0 0.057 13.2 0.0 1.6 1 0 0 1 1 1 0 Lysine methyltransferase Transferase PF02458.15 ORY03472.1 - 5.3e-11 41.8 0.0 5.6e-09 35.2 0.0 2.8 3 0 0 3 3 3 2 Transferase family Peptidase_M7 PF02031.16 ORY03472.1 - 0.16 12.1 0.0 0.29 11.2 0.0 1.4 1 0 0 1 1 1 0 Streptomyces extracellular neutral proteinase (M7) family WES_acyltransf PF03007.16 ORY03472.1 - 0.18 11.5 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 Wax ester synthase-like Acyl-CoA acyltransferase domain DUF3237 PF11578.8 ORY03473.1 - 3.9e-30 104.7 0.1 4.4e-30 104.5 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) GXWXG PF14231.6 ORY03473.1 - 0.12 12.5 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 GXWXG protein FAD_binding_3 PF01494.19 ORY03474.1 - 1.5e-23 83.6 0.0 4.5e-23 82.0 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 ORY03474.1 - 3.4e-06 26.9 2.3 2.2e-05 24.2 1.8 2.0 1 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ORY03474.1 - 4e-06 26.3 0.6 0.0019 17.5 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORY03474.1 - 5.9e-06 26.4 0.4 6.5e-05 23.1 0.5 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 ORY03474.1 - 1.8e-05 24.1 0.5 2.5e-05 23.6 0.5 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 ORY03474.1 - 7.4e-05 22.2 0.1 0.0002 20.7 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 ORY03474.1 - 0.00022 20.6 0.1 0.029 13.6 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.12 ORY03474.1 - 0.0066 15.6 0.4 0.022 13.8 0.4 1.8 1 1 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 ORY03474.1 - 0.039 13.2 0.0 0.065 12.5 0.0 1.3 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.14 ORY03474.1 - 0.063 12.0 0.3 0.11 11.1 0.3 1.4 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.22 ORY03474.1 - 0.073 12.1 0.1 0.24 10.4 0.3 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox PF00070.27 ORY03474.1 - 0.12 13.0 0.5 0.12 13.0 0.5 2.5 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase adh_short_C2 PF13561.6 ORY03475.1 - 3e-55 187.3 6.0 3.4e-55 187.2 6.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY03475.1 - 6.8e-43 146.4 4.8 8e-43 146.2 4.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORY03475.1 - 4.9e-10 39.6 1.7 8.2e-10 38.9 1.7 1.3 1 0 0 1 1 1 1 KR domain Ldh_1_N PF00056.23 ORY03475.1 - 0.0001 22.4 0.1 0.00027 21.1 0.1 1.6 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.6 ORY03476.1 - 1.5e-13 50.7 0.0 9.3e-12 44.8 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 ORY03476.1 - 9.4e-12 44.1 0.0 1.4e-07 30.3 0.0 2.8 3 0 0 3 3 3 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 ORY03476.1 - 2.9e-08 33.3 0.0 4.9e-05 22.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ORY03476.1 - 1.1e-07 31.3 0.0 1.1e-06 28.1 0.0 2.3 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 ORY03476.1 - 4.1e-07 30.1 0.7 0.021 14.8 0.1 3.3 2 1 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 ORY03476.1 - 6.4e-06 26.3 0.0 1.8e-05 24.9 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 ORY03476.1 - 0.00062 19.1 0.0 0.0011 18.2 0.0 1.3 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 ORY03476.1 - 0.0015 17.3 0.0 0.75 8.4 0.0 2.4 2 0 0 2 2 2 2 HI0933-like protein DAO PF01266.24 ORY03476.1 - 0.0049 16.5 3.2 3.9 7.0 1.6 3.2 2 1 0 3 3 3 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 ORY03476.1 - 0.0087 15.1 0.0 0.012 14.6 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 ORY03476.1 - 0.013 14.6 0.0 0.17 10.9 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain DUF2834 PF11196.8 ORY03477.1 - 0.023 15.0 8.4 0.042 14.2 1.5 3.2 3 1 1 4 4 4 0 Protein of unknown function (DUF2834) DUF805 PF05656.14 ORY03477.1 - 10 6.6 9.3 25 5.3 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF805) ketoacyl-synt PF00109.26 ORY03478.1 - 1.1e-70 238.1 0.0 2.6e-70 236.9 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.6 ORY03478.1 - 7.9e-70 235.4 0.0 1.3e-69 234.7 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 ORY03478.1 - 8e-59 198.6 0.6 2.4e-58 197.0 0.6 1.9 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.21 ORY03478.1 - 8.1e-56 189.8 0.0 2e-55 188.6 0.0 1.6 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 ORY03478.1 - 6.4e-29 100.4 0.0 2e-28 98.8 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 ORY03478.1 - 3.6e-22 79.0 0.0 1.7e-21 76.7 0.0 2.3 2 0 0 2 2 1 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 ORY03478.1 - 6e-11 42.2 0.6 1.9e-09 37.2 0.1 2.6 2 0 0 2 2 2 1 short chain dehydrogenase ADH_N PF08240.12 ORY03478.1 - 7.7e-06 25.8 0.0 1.8e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Thiolase_N PF00108.23 ORY03478.1 - 0.00042 19.8 0.2 0.0011 18.4 0.2 1.7 1 0 0 1 1 1 1 Thiolase, N-terminal domain ADH_zinc_N PF00107.26 ORY03478.1 - 0.00087 19.3 0.0 0.0034 17.4 0.0 2.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PP-binding PF00550.25 ORY03478.1 - 0.016 15.6 0.0 0.037 14.4 0.0 1.6 1 0 0 1 1 1 0 Phosphopantetheine attachment site ACP_syn_III PF08545.10 ORY03478.1 - 0.039 13.8 0.2 0.11 12.4 0.2 1.8 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III adh_short PF00106.25 ORY03480.1 - 1.2e-21 77.1 0.0 1.4e-16 60.6 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 ORY03480.1 - 5e-15 55.7 0.0 1.1e-10 41.4 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY03480.1 - 9.4e-06 25.7 0.0 1.4e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 ORY03480.1 - 0.14 12.4 0.0 0.27 11.5 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Zn_clus PF00172.18 ORY03481.1 - 1.3e-07 31.6 11.5 2.2e-07 30.9 11.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PilJ PF13675.6 ORY03481.1 - 0.14 12.2 3.7 7.4 6.6 0.2 2.6 2 1 1 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term KxDL PF10241.9 ORY03481.1 - 1.2 9.5 5.6 9 6.7 0.3 2.9 2 1 1 3 3 3 0 Uncharacterized conserved protein SH3BP5 PF05276.14 ORY03481.1 - 2.8 7.7 7.9 0.2 11.5 2.7 1.6 2 0 0 2 2 2 0 SH3 domain-binding protein 5 (SH3BP5) adh_short PF00106.25 ORY03482.1 - 4.2e-22 78.6 0.0 1.1e-16 60.9 0.0 2.0 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 ORY03482.1 - 2.5e-13 50.2 0.0 4.2e-12 46.1 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY03482.1 - 0.00012 22.0 0.0 0.00017 21.6 0.0 1.2 1 0 0 1 1 1 1 KR domain GMC_oxred_N PF00732.19 ORY03483.1 - 1.7e-54 185.2 0.0 2.3e-54 184.8 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 ORY03483.1 - 3.7e-35 121.5 0.0 5.9e-35 120.9 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 ORY03483.1 - 7.6e-08 32.3 0.8 0.0016 18.1 0.4 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 ORY03483.1 - 3.7e-05 23.0 1.1 0.17 10.9 0.5 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 ORY03483.1 - 0.0006 20.0 0.8 0.0017 18.5 0.8 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ORY03483.1 - 0.0028 16.9 0.2 0.087 12.0 0.2 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 ORY03483.1 - 0.0092 15.1 0.1 0.014 14.5 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox PF00070.27 ORY03483.1 - 0.092 13.3 0.7 9.7 6.8 0.0 3.0 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase p450 PF00067.22 ORY03484.1 - 6.5e-63 213.1 0.0 8.4e-63 212.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Apolipoprotein PF01442.18 ORY03485.1 - 0.0016 18.3 9.2 0.086 12.7 6.7 3.5 1 1 1 2 2 2 2 Apolipoprotein A1/A4/E domain XH PF03469.14 ORY03485.1 - 0.0088 16.0 11.6 0.75 9.7 0.2 4.3 2 1 2 4 4 4 2 XH domain Tam41_Mmp37 PF09139.11 ORY03485.1 - 0.018 14.5 0.5 0.032 13.7 0.5 1.4 1 0 0 1 1 1 0 Phosphatidate cytidylyltransferase, mitochondrial RE_HaeIII PF09556.10 ORY03485.1 - 0.02 14.0 0.9 0.059 12.4 0.0 2.0 2 0 0 2 2 2 0 HaeIII restriction endonuclease HisKA_3 PF07730.13 ORY03485.1 - 0.034 14.7 2.4 4.9 7.8 0.0 4.1 5 0 0 5 5 5 0 Histidine kinase HAUS-augmin3 PF14932.6 ORY03485.1 - 0.076 12.6 4.0 8.8 5.8 2.6 3.1 2 1 1 3 3 3 0 HAUS augmin-like complex subunit 3 CspB_prodomain PF18425.1 ORY03485.1 - 0.098 12.7 0.5 0.34 10.9 0.0 2.1 2 0 0 2 2 2 0 Csp protease B prodomain DUF4404 PF14357.6 ORY03485.1 - 0.14 12.8 10.9 19 5.9 0.0 4.6 4 1 2 6 6 6 0 Domain of unknown function (DUF4404) DnaI_N PF07319.11 ORY03485.1 - 0.15 12.7 2.7 0.18 12.5 0.3 2.5 2 1 0 2 2 2 0 Primosomal protein DnaI N-terminus DUF3235 PF11574.8 ORY03485.1 - 0.16 12.8 1.2 38 5.2 0.2 3.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3235) YtxH PF12732.7 ORY03485.1 - 0.16 12.5 24.2 15 6.2 2.5 5.5 1 1 2 3 3 3 0 YtxH-like protein Phasin_2 PF09361.10 ORY03485.1 - 0.29 11.4 7.4 5.5 7.3 0.1 3.9 4 0 0 4 4 4 0 Phasin protein Senescence PF06911.12 ORY03485.1 - 0.34 11.2 3.8 1.5 9.1 0.2 3.6 2 2 1 3 3 3 0 Senescence-associated protein Rep_fac_C PF08542.11 ORY03485.1 - 0.35 11.3 2.1 72 3.9 0.0 3.7 4 0 0 4 4 4 0 Replication factor C C-terminal domain FAM184 PF15665.5 ORY03485.1 - 0.73 9.6 12.0 9.3 6.0 0.0 3.4 3 0 0 3 3 3 0 Family with sequence similarity 184, A and B DUF883 PF05957.13 ORY03485.1 - 0.8 10.3 9.7 19 6.0 1.4 5.0 2 1 2 5 5 5 0 Bacterial protein of unknown function (DUF883) DUF4533 PF15047.6 ORY03485.1 - 1.1 8.8 9.5 0.055 13.0 0.9 2.9 3 1 1 4 4 4 0 Protein of unknown function (DUF4533) RRP36 PF06102.12 ORY03485.1 - 1.9 8.5 11.2 0.16 12.0 3.3 2.8 3 0 0 3 3 3 0 rRNA biogenesis protein RRP36 ApoLp-III PF07464.11 ORY03485.1 - 2.2 8.3 20.4 6.6 6.8 2.5 4.3 4 1 0 4 4 4 0 Apolipophorin-III precursor (apoLp-III) IL22 PF14565.6 ORY03485.1 - 2.7 8.2 4.4 4.2 7.6 0.2 2.9 2 1 0 3 3 3 0 Interleukin 22 IL-10-related T-cell-derived-inducible factor Fib_alpha PF08702.10 ORY03485.1 - 5.7 7.1 7.9 2 8.6 0.5 3.4 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Glyco_transf_34 PF05637.12 ORY03487.1 - 2.3e-54 184.6 0.0 2.9e-54 184.3 0.0 1.1 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.14 ORY03487.1 - 0.013 15.1 0.0 0.045 13.3 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function, DUF273 Yeast-kill-tox PF09207.11 ORY03488.1 - 0.072 13.7 0.1 0.12 13.0 0.1 1.3 1 0 0 1 1 1 0 Yeast killer toxin dCMP_cyt_deam_1 PF00383.23 ORY03489.1 - 5e-08 32.7 0.1 7.3e-08 32.2 0.1 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 ORY03489.1 - 7.1e-06 25.8 0.1 9.4e-06 25.4 0.1 1.3 1 0 0 1 1 1 1 MafB19-like deaminase APOBEC_N PF08210.11 ORY03489.1 - 0.00095 19.1 0.8 0.0017 18.2 0.8 1.5 1 1 0 1 1 1 1 APOBEC-like N-terminal domain SNAD4 PF18750.1 ORY03489.1 - 0.0023 18.0 0.6 0.0071 16.5 0.7 1.7 2 0 0 2 2 2 1 Secreted Novel AID/APOBEC-like Deaminase 4 NAD1 PF18778.1 ORY03489.1 - 0.0054 16.8 0.3 0.0085 16.2 0.3 1.4 1 0 0 1 1 1 1 Novel AID APOBEC clade 1 NAD2 PF18782.1 ORY03489.1 - 0.0065 16.6 0.2 0.01 16.0 0.2 1.4 1 0 0 1 1 1 1 Novel AID APOBEC clade 2 APOBEC3 PF18771.1 ORY03489.1 - 0.021 14.9 0.3 0.037 14.2 0.3 1.3 1 0 0 1 1 1 0 APOBEC3 Bd3614-deam PF14439.6 ORY03489.1 - 0.028 14.5 0.2 0.05 13.7 0.2 1.5 1 0 0 1 1 1 0 Bd3614-like deaminase APOBEC2 PF18772.1 ORY03489.1 - 0.044 13.8 2.6 0.078 13.0 2.1 1.5 1 1 0 1 1 1 0 APOBEC2 5-FTHF_cyc-lig PF01812.20 ORY03490.1 - 4.8e-13 49.4 0.0 6.7e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family Pescadillo_N PF06732.11 ORY03493.1 - 1.2e-122 408.7 0.7 1.8e-122 408.2 0.0 1.5 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT_2 PF16589.5 ORY03493.1 - 3.3e-05 24.2 0.0 0.00016 22.0 0.0 2.2 1 1 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 ORY03493.1 - 0.0016 18.8 0.0 0.0042 17.4 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 ORY03493.1 - 0.078 13.3 0.1 0.23 11.7 0.1 1.8 1 1 0 1 1 1 0 DNA ligase 3 BRCT domain PIG-U PF06728.13 ORY03494.1 - 7.5e-122 407.1 25.7 8.6e-122 406.9 25.7 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U 8TM_micro PF17028.5 ORY03494.1 - 1.2 8.8 8.5 5.1 6.7 8.5 1.9 1 1 0 1 1 1 0 8TM Microsporidial transmembrane domain DUF4661 PF15576.6 ORY03495.1 - 0.093 12.6 1.4 0.12 12.3 1.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) Hamartin PF04388.12 ORY03495.1 - 0.12 11.0 1.4 0.13 10.9 1.4 1.1 1 0 0 1 1 1 0 Hamartin protein Ubiquitin_2 PF14560.6 ORY03495.1 - 0.16 12.5 0.0 0.33 11.4 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-like domain Ets PF00178.22 ORY03495.1 - 0.16 12.4 0.2 1.4 9.5 0.0 2.4 2 1 0 2 2 2 0 Ets-domain MAP65_ASE1 PF03999.12 ORY03495.1 - 0.66 8.6 3.5 0.8 8.3 3.5 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) MutS_V PF00488.21 ORY03496.1 - 1.4e-66 224.2 0.1 3.4e-66 222.9 0.1 1.7 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 ORY03496.1 - 3.1e-41 141.7 0.0 7.8e-41 140.4 0.0 1.7 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 ORY03496.1 - 9.9e-33 112.8 0.1 3e-32 111.2 0.0 1.9 2 0 0 2 2 2 1 MutS domain I MutS_II PF05188.17 ORY03496.1 - 3e-13 50.2 0.0 8.7e-13 48.7 0.0 1.8 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 ORY03496.1 - 4.5e-09 36.5 0.2 1.3e-08 35.1 0.1 1.9 2 0 0 2 2 2 1 MutS family domain IV AAA_29 PF13555.6 ORY03496.1 - 0.081 12.7 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 ORY03496.1 - 0.088 13.3 0.0 0.41 11.1 0.1 2.1 2 0 0 2 2 2 0 AAA domain PBP1_TM PF14812.6 ORY03496.1 - 3.5 8.0 9.4 4.7 7.7 5.8 2.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal SBF_like PF13593.6 ORY03497.1 - 8.6e-92 307.8 24.7 9.9e-92 307.6 24.7 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) ASC PF00858.24 ORY03497.1 - 0.18 10.8 0.6 0.32 9.9 0.6 1.5 1 0 0 1 1 1 0 Amiloride-sensitive sodium channel Comm PF15957.5 ORY03497.1 - 2.7 8.4 6.2 0.2 12.0 0.3 2.2 3 0 0 3 3 3 0 Commissureless 2-Hacid_dh_C PF02826.19 ORY03498.1 - 3.4e-41 140.6 0.0 1.7e-39 135.0 0.0 2.2 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 ORY03498.1 - 2.2e-10 40.3 0.0 1.7e-09 37.4 0.0 2.0 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Caskin-Pro-rich PF16907.5 ORY03499.1 - 1.7 9.2 5.5 3 8.4 5.5 1.5 1 1 0 1 1 1 0 Proline rich region of Caskin proteins IBR PF01485.21 ORY03551.1 - 2.9e-19 69.1 21.1 3.5e-12 46.3 3.1 4.4 4 1 0 4 4 4 2 IBR domain, a half RING-finger domain HET PF06985.11 ORY03552.1 - 2.3e-25 89.7 4.5 1e-22 81.1 0.1 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) GST_C PF00043.25 ORY03554.1 - 9.1e-07 29.0 0.0 1.9e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 ORY03554.1 - 1.6e-05 24.8 0.2 3.2e-05 23.9 0.2 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 ORY03554.1 - 4.7e-05 23.6 0.0 0.00037 20.8 0.0 2.2 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 ORY03554.1 - 0.00011 22.5 0.0 0.00019 21.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 ORY03554.1 - 0.00094 19.4 0.0 0.002 18.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 ORY03554.1 - 0.00099 19.3 0.0 0.0022 18.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain PHD PF00628.29 ORY03556.1 - 8.2e-08 32.0 10.5 1.5e-07 31.2 10.5 1.4 1 0 0 1 1 1 1 PHD-finger ING PF12998.7 ORY03556.1 - 1.4e-05 25.6 1.5 1.8e-05 25.2 0.0 2.0 2 0 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding zf-HC5HC2H PF13771.6 ORY03556.1 - 0.056 13.7 3.0 0.12 12.6 3.0 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 ORY03556.1 - 0.066 13.4 1.6 0.12 12.5 1.6 1.4 1 0 0 1 1 1 0 PHD-zinc-finger like domain PIEZO PF15917.5 ORY03556.1 - 0.98 8.8 3.0 0.6 9.6 0.7 1.7 2 0 0 2 2 2 0 Piezo DEC-1_N PF04625.13 ORY03558.1 - 0.43 9.5 1.5 0.53 9.2 1.5 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region NACHT_N PF17100.5 ORY03559.1 - 2.4e-08 34.1 0.1 6.2e-08 32.8 0.1 1.7 1 1 0 1 1 1 1 N-terminal domain of NWD NACHT-NTPase NACHT PF05729.12 ORY03559.1 - 1.3e-07 31.7 0.0 3.3e-07 30.4 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 ORY03559.1 - 0.00011 22.4 0.0 0.00051 20.3 0.0 2.1 1 0 0 1 1 1 1 AAA domain KAP_NTPase PF07693.14 ORY03559.1 - 0.0005 19.4 0.5 0.024 13.9 0.3 2.4 1 1 1 2 2 2 1 KAP family P-loop domain AAA_16 PF13191.6 ORY03559.1 - 0.00065 20.1 0.2 0.007 16.8 0.0 2.8 2 1 0 2 2 2 1 AAA ATPase domain Methyltransf_2 PF00891.18 ORY03559.1 - 0.15 11.4 0.0 0.43 9.8 0.0 1.7 1 0 0 1 1 1 0 O-methyltransferase domain HCO3_cotransp PF00955.21 ORY03560.1 - 1.3e-84 284.9 15.2 1.8e-46 159.0 6.4 2.1 1 1 1 2 2 2 2 HCO3- transporter family HET PF06985.11 ORY03562.1 - 7.3e-24 84.8 1.4 8.7e-24 84.5 1.4 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) GATase PF00117.28 ORY03563.1 - 5.1e-10 39.4 0.0 6.9e-10 39.0 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 ORY03563.1 - 2.2e-06 27.6 0.6 2.6e-05 24.1 0.6 2.2 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.24 ORY03563.1 - 0.098 12.4 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 DJ-1/PfpI family Lipase_GDSL_2 PF13472.6 ORY03563.1 - 0.18 12.1 0.0 0.25 11.7 0.0 1.2 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family DUF924 PF06041.11 ORY03564.1 - 3.8e-20 72.8 0.0 7.4e-20 71.8 0.0 1.4 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF924) HU-CCDC81_euk_1 PF14908.6 ORY03564.1 - 0.13 12.4 0.0 0.28 11.4 0.0 1.5 1 0 0 1 1 1 0 CCDC81 eukaryotic HU domain 1 HlyIII PF03006.20 ORY03565.1 - 2e-51 174.9 19.2 2.8e-51 174.4 19.2 1.1 1 0 0 1 1 1 1 Haemolysin-III related ATP_synt_H PF05493.13 ORY03565.1 - 0.12 12.9 0.1 0.12 12.9 0.1 2.8 3 1 0 3 3 3 0 ATP synthase subunit H TssN PF17555.2 ORY03565.1 - 3.1 7.1 12.6 0.12 11.8 2.9 2.1 1 1 0 2 2 2 0 Type VI secretion system, TssN Colicin_V PF02674.16 ORY03565.1 - 4.7 7.2 11.8 1.3 9.0 1.9 2.4 1 1 1 2 2 2 0 Colicin V production protein Ank_2 PF12796.7 ORY03566.1 - 5.1e-11 43.0 0.0 3e-07 30.9 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY03566.1 - 1e-10 41.9 0.3 2.3e-07 31.2 0.0 3.0 3 0 0 3 3 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY03566.1 - 5e-09 35.7 0.3 0.087 13.4 0.0 4.5 4 0 0 4 4 3 2 Ankyrin repeat Ank PF00023.30 ORY03566.1 - 4.5e-08 33.2 0.6 0.16 12.4 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeat NACHT PF05729.12 ORY03566.1 - 1.6e-07 31.4 0.0 3.3e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 ORY03566.1 - 3.9e-07 30.6 0.4 1.5e-06 28.8 0.0 2.0 2 1 1 3 3 3 1 AAA ATPase domain Ank_5 PF13857.6 ORY03566.1 - 6.5e-05 23.1 0.0 0.12 12.7 0.0 2.9 3 0 0 3 3 2 2 Ankyrin repeats (many copies) ATPase PF06745.13 ORY03566.1 - 0.00046 19.6 0.0 0.00085 18.7 0.0 1.4 1 0 0 1 1 1 1 KaiC AAA_25 PF13481.6 ORY03566.1 - 0.00046 19.8 0.0 0.0032 17.1 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 ORY03566.1 - 0.00097 19.4 0.0 0.0028 17.9 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_14 PF13173.6 ORY03566.1 - 0.025 14.6 0.0 5.5 7.0 0.0 2.4 1 1 1 2 2 2 0 AAA domain Cas_Csy2 PF09614.10 ORY03566.1 - 0.068 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy2) DUF676 PF05057.14 ORY03567.1 - 2e-08 34.1 0.0 4.5e-08 32.9 0.0 1.5 1 1 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 ORY03567.1 - 7.8e-07 29.0 0.0 1.3e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 ORY03567.1 - 0.0007 20.3 0.0 0.0011 19.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Cutinase PF01083.22 ORY03567.1 - 0.0012 18.9 0.0 0.0024 17.9 0.0 1.5 1 0 0 1 1 1 1 Cutinase Abhydrolase_1 PF00561.20 ORY03567.1 - 0.002 17.8 0.0 0.0039 16.9 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_8 PF06259.12 ORY03567.1 - 0.01 15.5 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase Palm_thioest PF02089.15 ORY03567.1 - 0.02 14.7 0.0 0.043 13.7 0.0 1.5 1 1 0 1 1 1 0 Palmitoyl protein thioesterase Hydrolase_4 PF12146.8 ORY03567.1 - 0.028 13.7 0.0 0.063 12.5 0.0 1.6 1 0 0 1 1 1 0 Serine aminopeptidase, S33 LCAT PF02450.15 ORY03567.1 - 0.083 12.0 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase SBP56 PF05694.11 ORY03568.1 - 1.5e-09 37.2 0.0 5.5e-09 35.3 0.0 2.0 1 1 0 1 1 1 1 56kDa selenium binding protein (SBP56) Lactonase PF10282.9 ORY03568.1 - 0.0089 15.3 0.0 3.5 6.8 0.0 2.7 3 1 0 3 3 3 2 Lactonase, 7-bladed beta-propeller PQQ_3 PF13570.6 ORY03568.1 - 0.064 13.8 1.7 0.14 12.7 0.1 2.4 2 0 0 2 2 2 0 PQQ-like domain SGL PF08450.12 ORY03568.1 - 0.096 12.2 0.1 2 7.9 0.0 2.6 3 0 0 3 3 3 0 SMP-30/Gluconolactonase/LRE-like region Cupin_1 PF00190.22 ORY03569.1 - 2.5e-34 118.1 0.0 1.6e-17 63.5 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 ORY03569.1 - 3.2e-22 78.0 1.6 4.4e-11 42.3 0.1 2.5 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 ORY03569.1 - 1.5e-06 27.8 0.1 0.0058 16.3 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.19 ORY03569.1 - 5.2e-05 23.2 1.5 0.12 12.3 0.1 2.3 2 0 0 2 2 2 2 AraC-like ligand binding domain Cupin_6 PF12852.7 ORY03569.1 - 0.0092 15.7 0.0 4.1 7.1 0.0 2.3 2 0 0 2 2 2 2 Cupin WBP-1 PF11669.8 ORY03570.1 - 0.16 12.7 2.3 0.18 12.5 0.1 2.2 2 0 0 2 2 2 0 WW domain-binding protein 1 TssO PF17561.2 ORY03570.1 - 5.6 7.1 5.1 0.59 10.2 0.1 2.0 2 0 0 2 2 2 0 Type VI secretion system, TssO p450 PF00067.22 ORY03571.1 - 5.7e-27 94.6 0.0 7.8e-27 94.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 ORY03573.1 - 3.4e-08 32.7 0.0 8.7e-08 31.3 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 ABC2_membrane PF01061.24 ORY03574.1 - 1.8e-74 249.7 35.7 2e-39 135.2 12.5 2.6 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 ORY03574.1 - 7.2e-39 133.4 0.0 1.2e-18 68.0 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 ORY03574.1 - 2.7e-22 78.5 5.2 2.5e-20 72.2 0.0 3.5 4 0 0 4 4 3 2 CDR ABC transporter ABC2_membrane_3 PF12698.7 ORY03574.1 - 6.8e-09 35.3 22.3 8.4e-05 21.8 6.2 2.6 3 0 0 3 3 3 2 ABC-2 family transporter protein AAA_25 PF13481.6 ORY03574.1 - 3.4e-08 33.3 0.7 0.00021 20.9 0.1 3.2 2 1 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 ORY03574.1 - 1.9e-05 24.6 0.1 0.0031 17.5 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 ORY03574.1 - 4.3e-05 23.2 0.3 0.088 12.6 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.19 ORY03574.1 - 6.3e-05 22.5 0.0 0.62 9.5 0.0 3.3 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 ORY03574.1 - 0.00032 21.1 0.1 0.6 10.5 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_33 PF13671.6 ORY03574.1 - 0.00036 20.7 0.0 0.054 13.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 ORY03574.1 - 0.0015 19.1 0.0 0.28 11.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 ORY03574.1 - 0.0031 17.5 0.5 0.91 9.4 0.1 2.7 2 0 0 2 2 2 1 NACHT domain AAA_21 PF13304.6 ORY03574.1 - 0.004 17.0 0.0 1.6 8.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 ORY03574.1 - 0.0061 16.8 0.0 1.5 9.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 ORY03574.1 - 0.0071 16.8 0.2 0.39 11.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 ORY03574.1 - 0.015 15.4 0.1 7.9 6.6 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase ABC_trans_N PF14510.6 ORY03574.1 - 0.021 15.4 0.0 0.057 14.0 0.0 1.8 1 0 0 1 1 1 0 ABC-transporter N-terminal AAA_30 PF13604.6 ORY03574.1 - 0.048 13.4 0.3 2.1 8.0 0.1 2.3 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 ORY03574.1 - 0.07 12.5 0.4 13 5.0 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_28 PF13521.6 ORY03574.1 - 0.13 12.5 0.0 8.1 6.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 ORY03574.1 - 0.15 12.6 0.0 0.35 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 ORY03574.1 - 0.35 10.4 2.1 2 8.0 0.4 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF1129 PF06570.11 ORY03574.1 - 5.1 6.5 6.9 13 5.2 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) DUF3384 PF11864.8 ORY03576.1 - 2.2e-104 350.0 3.2 3.5e-104 349.4 3.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3384) Rap_GAP PF02145.15 ORY03576.1 - 5.3e-51 172.8 0.0 1.4e-50 171.4 0.0 1.8 2 0 0 2 2 2 1 Rap/ran-GAP Tuberin PF03542.16 ORY03576.1 - 1.7e-35 122.8 9.3 2.5e-33 115.6 1.6 3.2 3 0 0 3 3 3 2 Tuberin CAS_CSE1 PF03378.15 ORY03577.1 - 3.5e-185 615.7 0.6 3.5e-185 615.7 0.6 2.4 4 0 0 4 4 4 1 CAS/CSE protein, C-terminus Cse1 PF08506.10 ORY03577.1 - 4.3e-146 486.5 4.1 6.2e-146 486.0 4.1 1.2 1 0 0 1 1 1 1 Cse1 IBN_N PF03810.19 ORY03577.1 - 4.5e-15 55.3 0.4 2.3e-14 53.1 0.1 2.5 3 0 0 3 3 3 1 Importin-beta N-terminal domain Xpo1 PF08389.12 ORY03577.1 - 0.0037 17.3 0.1 0.064 13.3 0.0 3.2 3 1 0 3 3 3 1 Exportin 1-like protein DUF87 PF01935.17 ORY03577.1 - 0.14 12.3 0.1 0.58 10.2 0.1 2.0 2 0 0 2 2 2 0 Helicase HerA, central domain ECH_1 PF00378.20 ORY03578.1 - 7.6e-14 51.6 0.0 5.6e-13 48.8 0.0 2.0 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ORY03578.1 - 6.9e-13 48.8 0.0 9.7e-13 48.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase DUF1640 PF07798.11 ORY03579.1 - 2e-41 141.9 0.4 2.6e-41 141.6 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) DUF3144 PF11342.8 ORY03579.1 - 0.031 14.6 0.3 0.063 13.6 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3144) DUF2353 PF09789.9 ORY03579.1 - 0.067 12.5 1.2 0.11 11.9 1.2 1.3 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) Pet100 PF09803.9 ORY03580.1 - 2.5e-21 76.0 1.1 3.1e-21 75.7 1.1 1.1 1 0 0 1 1 1 1 Pet100 Auts2 PF15336.6 ORY03580.1 - 2.1 8.5 5.4 2.4 8.2 5.4 1.0 1 0 0 1 1 1 0 Autism susceptibility gene 2 protein Transcrip_reg PF01709.20 ORY03581.1 - 8.5e-67 225.1 6.5 1.5e-65 221.0 6.5 2.0 1 1 0 1 1 1 1 Transcriptional regulator 1-cysPrx_C PF10417.9 ORY03581.1 - 0.11 12.3 0.4 0.81 9.6 0.1 2.3 2 0 0 2 2 2 0 C-terminal domain of 1-Cys peroxiredoxin HEAT PF02985.22 ORY03582.1 - 1.2e-11 43.8 12.8 2.8 8.4 0.0 9.9 9 0 0 9 9 9 3 HEAT repeat HEAT_2 PF13646.6 ORY03582.1 - 7.1e-10 39.1 6.7 0.027 14.9 0.0 8.1 6 2 3 9 9 9 3 HEAT repeats Vac14_Fab1_bd PF12755.7 ORY03582.1 - 0.0024 18.4 0.0 0.1 13.2 0.0 3.7 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 ORY03582.1 - 0.024 13.2 0.2 10 4.5 0.0 4.2 4 0 0 4 4 4 0 Adaptin N terminal region CLASP_N PF12348.8 ORY03582.1 - 0.041 13.4 0.6 37 3.8 0.0 4.7 5 1 1 6 6 6 0 CLASP N terminal Arm PF00514.23 ORY03582.1 - 0.041 13.9 2.3 23 5.2 0.5 4.9 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 ORY03582.1 - 0.053 14.1 23.6 3.2 8.4 0.1 9.9 12 1 2 14 14 14 0 HEAT-like repeat TrbC PF04956.13 ORY03582.1 - 2.7 8.3 6.3 19 5.6 0.1 3.8 3 0 0 3 3 3 0 TrbC/VIRB2 family DUF3684 PF12449.8 ORY03583.1 - 0 1176.5 0.0 0 1176.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) HATPase_c_3 PF13589.6 ORY03583.1 - 0.016 15.0 0.0 0.055 13.3 0.0 1.9 1 1 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ThrE_2 PF12821.7 ORY03583.1 - 0.045 13.9 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 Threonine/Serine exporter, ThrE WLM PF08325.10 ORY03583.1 - 0.05 13.7 0.1 0.14 12.2 0.1 1.7 1 0 0 1 1 1 0 WLM domain TRAPPC9-Trs120 PF08626.11 ORY03584.1 - 0 1444.3 0.0 0 1444.1 0.0 1.0 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit F-box PF00646.33 ORY03585.1 - 0.0024 17.7 0.1 0.0091 15.9 0.0 2.0 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 ORY03585.1 - 0.0041 17.0 0.0 0.011 15.6 0.0 1.8 1 0 0 1 1 1 1 F-box-like ATP-synt_DE_N PF02823.16 ORY03585.1 - 0.065 13.1 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 ATP synthase, Delta/Epsilon chain, beta-sandwich domain zf-H2C2_2 PF13465.6 ORY03641.1 - 1.8e-05 24.9 12.2 3e-05 24.2 3.4 5.1 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2 PF00096.26 ORY03641.1 - 5.7e-05 23.3 14.0 0.0017 18.7 4.4 3.4 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 ORY03641.1 - 0.019 15.0 2.0 6.5 6.9 0.4 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger FOXP-CC PF16159.5 ORY03641.1 - 0.075 13.7 2.3 0.37 11.5 0.1 2.7 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-C2H2_jaz PF12171.8 ORY03641.1 - 1.3 9.4 9.0 0.31 11.4 0.4 3.4 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Rad51 PF08423.11 ORY03643.1 - 1.7e-07 30.8 0.0 3e-06 26.7 0.0 2.3 1 1 0 1 1 1 1 Rad51 ATPase PF06745.13 ORY03643.1 - 6.8e-07 28.9 0.1 1.7e-06 27.6 0.0 1.6 2 0 0 2 2 2 1 KaiC AAA_25 PF13481.6 ORY03643.1 - 5.2e-05 22.9 0.6 0.00076 19.1 0.6 2.5 1 1 0 1 1 1 1 AAA domain RecA PF00154.21 ORY03643.1 - 5.3e-05 22.8 0.0 9.4e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 recA bacterial DNA recombination protein IstB_IS21 PF01695.17 ORY03643.1 - 0.0015 18.3 0.1 0.0028 17.4 0.1 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein ATPase_2 PF01637.18 ORY03643.1 - 0.0064 16.4 0.0 0.011 15.7 0.0 1.2 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_24 PF13479.6 ORY03643.1 - 0.067 12.9 0.1 0.42 10.3 0.1 2.0 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 ORY03643.1 - 0.072 12.5 0.1 0.15 11.5 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein CbiA PF01656.23 ORY03643.1 - 0.14 12.2 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain MOSC PF03473.17 ORY03644.1 - 6.1e-27 94.2 0.0 1e-26 93.5 0.0 1.4 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 ORY03644.1 - 6.4e-13 48.6 0.0 1.2e-12 47.8 0.0 1.5 1 1 0 1 1 1 1 MOSC N-terminal beta barrel domain Flavi_M PF01004.19 ORY03645.1 - 0.11 12.3 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Flavivirus envelope glycoprotein M zf-RING_2 PF13639.6 ORY03647.1 - 5.8e-10 39.3 7.0 1.6e-09 37.9 7.0 1.8 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 ORY03647.1 - 2.4e-09 37.3 5.8 2.4e-09 37.3 5.8 1.8 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 ORY03647.1 - 1.1e-06 28.6 2.8 1.1e-06 28.6 2.8 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 ORY03647.1 - 2.8e-06 27.2 4.7 5.5e-06 26.2 4.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 ORY03647.1 - 1.6e-05 24.8 3.1 3.6e-05 23.7 3.1 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 ORY03647.1 - 3.1e-05 24.0 0.9 8.7e-05 22.6 0.9 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 ORY03647.1 - 0.00013 21.8 0.5 0.00013 21.8 0.5 2.0 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 ORY03647.1 - 0.004 17.0 1.5 0.004 17.0 1.5 2.0 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 ORY03647.1 - 0.012 15.5 5.4 0.012 15.5 5.4 2.5 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 ORY03647.1 - 0.03 14.2 4.7 0.089 12.7 4.7 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Peptidase_S78_2 PF14550.6 ORY03647.1 - 0.091 12.8 0.1 0.19 11.8 0.1 1.5 1 0 0 1 1 1 0 Putative phage serine protease XkdF DUF2464 PF10240.9 ORY03647.1 - 0.15 11.6 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 Multivesicular body subunit 12 ETC_C1_NDUFA5 PF04716.14 ORY03648.1 - 3.7e-25 87.5 0.1 3.2e-23 81.3 0.0 2.4 2 0 0 2 2 2 2 ETC complex I subunit conserved region Thioredoxin PF00085.20 ORY03649.1 - 2.3e-44 149.6 0.4 2.1e-23 82.2 0.0 4.4 3 1 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 ORY03649.1 - 2.2e-10 40.8 0.0 3.2e-05 23.9 0.0 4.0 3 1 1 4 4 4 3 Thioredoxin-like domain Thioredoxin_8 PF13905.6 ORY03649.1 - 9.9e-06 25.8 0.6 0.32 11.4 0.0 3.6 3 0 0 3 3 3 2 Thioredoxin-like OST3_OST6 PF04756.13 ORY03649.1 - 8.5e-05 22.0 0.1 0.0084 15.5 0.1 2.4 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 ORY03649.1 - 0.00029 21.2 2.2 0.13 12.8 0.2 3.6 3 1 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 ORY03649.1 - 0.04 14.1 0.5 0.3 11.3 0.1 2.6 2 0 0 2 2 2 0 Thioredoxin-like Orthopox_C10L PF07020.11 ORY03649.1 - 0.16 12.7 1.5 0.3 11.8 1.5 1.4 1 0 0 1 1 1 0 Orthopoxvirus C10L protein Shisa PF13908.6 ORY03650.1 - 0.069 13.4 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator PAS_3 PF08447.12 ORY03652.1 - 4.1e-10 39.8 0.0 8.5e-08 32.4 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 ORY03652.1 - 2.1e-05 24.7 0.0 0.0017 18.6 0.0 2.4 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 ORY03652.1 - 2.6e-05 24.2 0.0 0.0056 16.7 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_11 PF14598.6 ORY03652.1 - 5.4e-05 23.3 0.0 0.00011 22.3 0.0 1.6 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 ORY03652.1 - 0.0003 21.0 0.0 0.15 12.3 0.0 2.8 3 0 0 3 3 3 2 PAS fold DUF448 PF04296.13 ORY03652.1 - 0.13 12.1 0.0 0.52 10.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF448) WD40 PF00400.32 ORY03654.1 - 5.3e-13 49.2 5.5 0.00054 20.7 0.0 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY03654.1 - 0.00023 21.4 0.0 6.3 7.2 0.0 3.6 2 1 0 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Fungal_trans PF04082.18 ORY03657.1 - 1.6e-16 60.1 0.4 3.2e-16 59.2 0.4 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.6 ORY03657.1 - 5.4e-09 36.1 11.0 9.4e-07 29.0 4.1 2.6 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORY03657.1 - 0.0012 19.5 19.8 0.038 14.8 6.0 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-Di19 PF05605.12 ORY03657.1 - 0.02 15.2 5.6 0.042 14.2 5.6 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.26 ORY03657.1 - 0.04 14.4 17.7 0.4 11.2 7.8 2.9 2 0 0 2 2 2 0 Zinc finger, C2H2 type Zn_Tnp_IS1595 PF12760.7 ORY03657.1 - 0.7 9.9 3.1 1.9 8.5 3.1 1.7 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Zn_ribbon_SprT PF17283.2 ORY03657.1 - 3.7 7.5 7.1 9.1 6.3 7.1 1.7 1 0 0 1 1 1 0 SprT-like zinc ribbon domain Peptidase_M3 PF01432.20 ORY03659.1 - 7.7e-159 529.8 0.0 1e-158 529.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 Pro_isomerase PF00160.21 ORY03660.1 - 5.3e-05 23.5 0.0 9.2e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD U-box PF04564.15 ORY03661.1 - 1.5e-22 79.5 0.0 3.2e-22 78.5 0.0 1.6 1 0 0 1 1 1 1 U-box domain TPR_1 PF00515.28 ORY03661.1 - 3.2e-12 45.7 1.6 6.3e-06 25.8 0.2 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 ORY03661.1 - 4.9e-11 41.9 1.2 7.1e-05 22.6 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 ORY03661.1 - 3.2e-08 33.1 0.2 1e-07 31.5 0.2 2.0 2 0 0 2 2 2 1 TPR repeat TPR_7 PF13176.6 ORY03661.1 - 1.9e-05 24.3 0.1 0.015 15.3 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY03661.1 - 5.4e-05 23.4 2.0 0.0016 18.6 0.3 2.7 1 1 2 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 ORY03661.1 - 0.00049 20.3 1.9 0.089 13.2 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 ORY03661.1 - 0.00094 19.6 0.2 0.21 12.2 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat CHIP_TPR_N PF18391.1 ORY03661.1 - 0.0013 19.5 0.5 0.0026 18.5 0.5 1.6 1 0 0 1 1 1 1 CHIP N-terminal tetratricopeptide repeat domain TPR_12 PF13424.6 ORY03661.1 - 0.0023 18.2 2.1 1.9 8.9 0.1 3.3 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 ORY03661.1 - 0.0045 17.6 0.0 0.022 15.4 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat zf-NOSIP PF15906.5 ORY03661.1 - 0.0086 16.2 0.0 0.03 14.5 0.0 1.9 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein DNA_pol3_finger PF17657.1 ORY03661.1 - 0.02 14.3 0.0 0.035 13.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial DNA polymerase III alpha subunit finger domain TPR_8 PF13181.6 ORY03661.1 - 0.04 14.1 1.5 0.1 12.9 0.1 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Peptidase_M1 PF01433.20 ORY03662.1 - 3.1e-40 138.1 0.0 5.2e-40 137.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 ORY03662.1 - 4.1e-35 120.3 0.0 8.5e-35 119.3 0.0 1.6 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 ORY03662.1 - 2.5e-31 109.3 0.1 3.9e-31 108.7 0.1 1.2 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_M61 PF05299.12 ORY03662.1 - 2.1 8.8 5.4 4.5 7.7 2.5 2.5 2 1 0 2 2 2 0 M61 glycyl aminopeptidase LysM PF01476.20 ORY03663.1 - 0.047 13.8 0.0 0.089 12.9 0.0 1.5 1 0 0 1 1 1 0 LysM domain NUDIX PF00293.28 ORY03665.1 - 6.7e-22 77.9 0.4 9.4e-22 77.5 0.4 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 ORY03665.1 - 0.017 15.1 0.0 0.027 14.5 0.0 1.4 1 0 0 1 1 1 0 NUDIX domain Fungal_trans PF04082.18 ORY03666.1 - 1.1e-31 109.8 0.0 3.1e-31 108.4 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY03666.1 - 1e-07 32.0 8.7 1.7e-07 31.3 8.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LacAB_rpiB PF02502.18 ORY03668.1 - 2.4e-46 157.2 0.2 2.7e-46 157.0 0.2 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase Gly_rich_SFCGS PF14272.6 ORY03668.1 - 0.073 13.1 0.3 0.85 9.7 0.1 2.1 1 1 0 2 2 2 0 Glycine-rich SFCGS Rhodanese PF00581.20 ORY03669.1 - 3.9e-13 49.9 0.0 5.1e-13 49.5 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain HET PF06985.11 ORY03670.1 - 7.1e-26 91.3 4.4 1.1e-24 87.5 0.1 2.1 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) DUF664 PF04978.12 ORY03670.1 - 0.14 12.6 0.1 1.5 9.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF664) MFS_1 PF07690.16 ORY03674.1 - 9e-25 87.3 75.6 2.6e-23 82.6 47.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Zn_clus PF00172.18 ORY03675.1 - 3.3e-06 27.1 13.7 3.3e-06 27.1 13.7 2.0 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ORY03675.1 - 0.094 11.7 1.0 0.19 10.7 1.0 1.4 1 0 0 1 1 1 0 Fungal specific transcription factor domain Lipase_GDSL_2 PF13472.6 ORY03676.1 - 4e-05 24.1 0.0 9.9e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family zf-MYND PF01753.18 ORY03678.1 - 1.6e-10 40.9 8.1 2.7e-10 40.2 8.1 1.4 1 0 0 1 1 1 1 MYND finger TraC_F_IV PF11130.8 ORY03679.1 - 0.083 12.5 0.1 0.19 11.3 0.1 1.5 1 1 0 1 1 1 0 F pilus assembly Type-IV secretion system for plasmid transfer SLX9 PF15341.6 ORY03679.1 - 1.8 9.0 5.8 3.3 8.1 5.8 1.5 1 0 0 1 1 1 0 Ribosome biogenesis protein SLX9 LMBR1 PF04791.16 ORY03679.1 - 2.2 7.1 6.2 3 6.7 6.2 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein TF_AP-2 PF03299.14 ORY03679.1 - 4.5 7.2 8.5 1.9 8.4 3.3 2.7 2 2 0 2 2 2 0 Transcription factor AP-2 adh_short PF00106.25 ORY03680.1 - 2.9e-36 124.8 0.0 1.7e-27 96.1 0.0 2.1 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 ORY03680.1 - 3.4e-22 79.2 0.0 2.9e-16 59.8 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY03680.1 - 1e-09 38.5 0.0 1.8e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 ORY03680.1 - 0.0022 17.2 0.0 0.0033 16.6 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 ORY03680.1 - 0.0054 16.2 0.1 0.015 14.7 0.0 1.6 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 ORY03680.1 - 0.0065 16.0 0.0 0.039 13.4 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 ORY03680.1 - 0.15 11.0 0.0 0.24 10.4 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family EAP30 PF04157.16 ORY03681.1 - 2.5e-42 144.8 0.2 3.2e-42 144.5 0.2 1.1 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36-NZF-N PF16988.5 ORY03681.1 - 1.1e-23 82.4 1.9 1.1e-23 82.4 1.9 2.6 2 1 0 2 2 2 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain Vps36_ESCRT-II PF11605.8 ORY03681.1 - 3.9e-22 78.2 0.0 6.2e-22 77.6 0.0 1.3 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 zf-Sec23_Sec24 PF04810.15 ORY03681.1 - 3.8e-06 26.8 5.2 0.0019 18.2 0.2 2.5 2 0 0 2 2 2 2 Sec23/Sec24 zinc finger zf-RanBP PF00641.18 ORY03681.1 - 0.0043 16.3 13.5 0.0076 15.5 1.1 2.8 3 0 0 3 3 3 2 Zn-finger in Ran binding protein and others DZR PF12773.7 ORY03681.1 - 0.057 13.5 4.4 0.063 13.3 0.5 2.4 2 0 0 2 2 2 0 Double zinc ribbon GRAM PF02893.20 ORY03681.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 GRAM domain SAC3_GANP PF03399.16 ORY03682.1 - 7.1e-27 94.5 0.3 8.5e-25 87.7 0.3 2.2 1 1 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 ORY03682.1 - 0.0001 22.3 0.1 0.0022 18.0 0.0 2.3 2 0 0 2 2 2 1 CSN8/PSMD8/EIF3K family TCP PF03634.13 ORY03682.1 - 0.0095 16.5 5.2 0.37 11.4 0.0 2.3 2 0 0 2 2 2 1 TCP family transcription factor PCI PF01399.27 ORY03682.1 - 0.16 12.5 0.0 0.47 11.0 0.0 1.9 1 1 0 1 1 1 0 PCI domain SH3_1 PF00018.28 ORY03684.1 - 7.6e-25 86.3 0.0 1.5e-11 43.7 0.0 2.8 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 ORY03684.1 - 4.5e-17 61.7 0.2 6.8e-08 32.2 0.2 2.8 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.17 ORY03684.1 - 8.6e-14 51.0 0.0 1.4e-09 37.5 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain PX PF00787.24 ORY03684.1 - 1.5e-11 44.2 0.0 3.1e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 PX domain PB1 PF00564.24 ORY03684.1 - 6.7e-05 22.7 0.1 0.00012 22.0 0.1 1.4 1 0 0 1 1 1 1 PB1 domain SPX PF03105.19 ORY03684.1 - 0.98 9.3 11.7 1.7 8.5 9.0 2.4 2 1 0 2 2 2 0 SPX domain Glyco_hydro_7 PF00840.20 ORY03728.1 - 6.5e-92 308.5 0.3 7.3e-92 308.4 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 HIM1 PF08732.10 ORY03730.1 - 2.5e-08 33.6 0.0 1.2e-07 31.5 0.0 1.7 1 1 1 2 2 2 1 HIM1 NAD_binding_10 PF13460.6 ORY03730.1 - 0.00026 20.9 0.0 0.00041 20.3 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 ORY03730.1 - 0.002 17.6 0.0 0.0036 16.8 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 ORY03730.1 - 0.049 12.8 0.0 0.14 11.3 0.0 1.7 2 0 0 2 2 2 0 Male sterility protein Semialdhyde_dh PF01118.24 ORY03730.1 - 0.1 13.1 0.0 0.22 12.0 0.0 1.8 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 ORY03731.1 - 6.7e-58 195.0 0.3 1.9e-57 193.5 0.0 1.8 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 ORY03731.1 - 7e-39 132.6 0.2 1.5e-38 131.5 0.2 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain XdhC_C PF13478.6 ORY03731.1 - 0.016 15.7 0.0 0.044 14.3 0.0 1.8 1 0 0 1 1 1 0 XdhC Rossmann domain Glyoxalase PF00903.25 ORY03732.1 - 4.6e-40 136.8 0.1 1.2e-19 70.8 0.1 2.1 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 ORY03732.1 - 7e-14 52.0 0.1 8.8e-07 29.2 0.0 3.6 1 1 2 3 3 3 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 ORY03732.1 - 4.7e-08 33.8 0.0 0.0022 18.8 0.0 2.8 2 1 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_3 PF13468.6 ORY03732.1 - 1.2e-06 28.7 0.0 0.084 13.0 0.0 2.8 2 1 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_2 PF12681.7 ORY03732.1 - 9.5e-06 25.5 1.5 3.9 7.4 0.2 4.4 3 1 0 3 3 3 3 Glyoxalase-like domain MoaF PF10703.9 ORY03732.1 - 0.014 15.3 0.1 0.66 9.9 0.0 2.3 2 0 0 2 2 2 0 MoaF N-terminal domain PRT_C PF08372.10 ORY03732.1 - 0.02 14.6 0.0 1.8 8.3 0.0 2.2 2 0 0 2 2 2 0 Plant phosphoribosyltransferase C-terminal DUF1338 PF07063.13 ORY03732.1 - 0.046 12.9 0.0 7.7 5.6 0.0 3.1 4 0 0 4 4 4 0 Domain of unknown function (DUF1338) MOSC PF03473.17 ORY03734.1 - 1.3e-23 83.5 0.0 2.9e-23 82.3 0.0 1.6 1 0 0 1 1 1 1 MOSC domain Fer2 PF00111.27 ORY03734.1 - 1.4e-12 47.3 2.4 3.3e-12 46.2 2.4 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain 3-alpha PF03475.14 ORY03734.1 - 5.3e-09 35.8 0.2 1.2e-08 34.6 0.0 1.7 2 0 0 2 2 2 1 3-alpha domain NAD_binding_1 PF00175.21 ORY03734.1 - 0.0092 16.6 0.1 0.87 10.3 0.0 2.4 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 ORY03734.1 - 0.011 15.8 0.0 4 7.5 0.0 2.3 2 0 0 2 2 2 0 Ferric reductase NAD binding domain DUF2083 PF09856.9 ORY03737.1 - 0.013 15.3 1.3 0.017 14.9 1.3 1.3 1 0 0 1 1 1 0 Predicted transcriptional regulator (DUF2083) zf-CCHC_2 PF13696.6 ORY03737.1 - 6.9 6.6 8.4 4.4 7.2 2.5 2.5 2 0 0 2 2 2 0 Zinc knuckle ABC_tran PF00005.27 ORY03739.1 - 3.8e-32 111.6 0.0 6.4e-32 110.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 ORY03739.1 - 5.9e-30 104.8 8.9 1.1e-29 103.9 8.9 1.5 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 ORY03739.1 - 0.00082 18.9 0.0 0.01 15.3 0.0 1.5 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_10 PF12846.7 ORY03739.1 - 0.0018 17.3 0.0 0.0029 16.6 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain AAA_16 PF13191.6 ORY03739.1 - 0.049 14.0 0.1 0.15 12.4 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 ORY03739.1 - 0.055 13.4 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase SbcCD_C PF13558.6 ORY03739.1 - 0.084 13.1 0.1 0.69 10.2 0.1 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_7 PF12775.7 ORY03739.1 - 0.088 12.3 0.0 2.2 7.8 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region Zeta_toxin PF06414.12 ORY03739.1 - 0.18 11.1 0.0 0.39 10.0 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_29 PF13555.6 ORY03739.1 - 0.19 11.5 0.3 0.63 9.8 0.1 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain p450 PF00067.22 ORY03741.1 - 6.2e-81 272.5 0.0 7e-81 272.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DivIC PF04977.15 ORY03744.1 - 0.005 16.6 0.3 0.005 16.6 0.3 2.8 3 0 0 3 3 3 1 Septum formation initiator Sas10 PF09368.10 ORY03744.1 - 7.5 7.1 7.7 1.1 9.7 1.5 2.7 2 0 0 2 2 2 0 Sas10 C-terminal domain HeLo PF14479.6 ORY03747.1 - 4.3e-27 95.3 0.1 7.7e-27 94.5 0.1 1.4 1 0 0 1 1 1 1 Prion-inhibition and propagation adh_short PF00106.25 ORY03748.1 - 0.021 14.3 0.0 0.12 11.8 0.0 2.0 2 0 0 2 2 2 0 short chain dehydrogenase SH3_3 PF08239.11 ORY03748.1 - 0.14 12.5 0.4 0.37 11.1 0.4 1.7 1 0 0 1 1 1 0 Bacterial SH3 domain Pkinase PF00069.25 ORY03749.1 - 6.2e-21 74.9 0.0 1e-20 74.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY03749.1 - 1.8e-19 70.1 0.0 3.1e-19 69.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_2 PF12796.7 ORY03749.1 - 1.8e-16 60.5 0.0 1.1e-05 25.9 0.0 5.4 5 0 0 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY03749.1 - 2.6e-13 50.2 2.6 0.013 16.0 0.0 6.6 5 1 1 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY03749.1 - 2.2e-10 39.8 12.8 0.0005 20.3 0.0 7.5 9 0 0 9 9 9 3 Ankyrin repeat Ank_5 PF13857.6 ORY03749.1 - 5.2e-09 36.2 2.1 0.0002 21.6 0.0 4.9 6 0 0 6 6 6 2 Ankyrin repeats (many copies) Ank PF00023.30 ORY03749.1 - 2e-06 28.0 12.9 0.0021 18.4 0.0 6.3 6 0 0 6 6 6 2 Ankyrin repeat adh_short PF00106.25 ORY03750.1 - 8.9e-21 74.2 0.0 1.4e-19 70.4 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY03750.1 - 1.4e-13 50.9 0.0 7.7e-13 48.5 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase FAD_binding_3 PF01494.19 ORY03751.1 - 3.3e-19 69.3 0.0 6e-19 68.5 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 ORY03751.1 - 2.1e-10 40.4 0.1 3.7e-05 23.1 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ORY03751.1 - 2.3e-07 29.9 0.2 0.00063 18.6 0.1 2.3 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.24 ORY03751.1 - 2.4e-07 30.2 1.3 4.4e-07 29.3 0.7 1.7 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 ORY03751.1 - 5.5e-06 26.0 0.0 8.1e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ORY03751.1 - 5.8e-06 26.5 0.4 1.5e-05 25.2 0.1 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ORY03751.1 - 6e-06 26.1 4.0 0.00069 19.3 1.0 2.5 1 1 0 2 2 2 2 FAD dependent oxidoreductase GIDA PF01134.22 ORY03751.1 - 1.9e-05 23.9 0.1 4.6e-05 22.7 0.0 1.6 2 0 0 2 2 2 1 Glucose inhibited division protein A 3HCDH_N PF02737.18 ORY03751.1 - 0.0018 18.2 0.1 0.0037 17.2 0.1 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.27 ORY03751.1 - 0.003 18.1 0.2 0.19 12.3 0.2 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 ORY03751.1 - 0.0057 15.7 0.3 0.017 14.2 0.3 1.7 1 1 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 ORY03751.1 - 0.032 13.5 0.1 0.067 12.4 0.1 1.5 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.6 ORY03751.1 - 0.11 11.7 0.5 0.71 9.1 0.2 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_2 PF00891.18 ORY03752.1 - 2.5e-17 62.9 0.0 2.4e-16 59.7 0.0 2.0 1 1 0 1 1 1 1 O-methyltransferase domain Methyltransf_25 PF13649.6 ORY03752.1 - 0.0011 19.6 0.0 0.0026 18.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ORY03752.1 - 0.032 13.8 0.0 0.056 13.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_16 PF10294.9 ORY03752.1 - 0.037 13.7 0.0 0.065 13.0 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_12 PF08242.12 ORY03752.1 - 0.062 14.1 0.0 0.18 12.6 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain ADH_N PF08240.12 ORY03753.1 - 3.7e-19 68.6 1.3 6.8e-19 67.8 1.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORY03753.1 - 4.1e-14 52.7 0.0 7e-14 51.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_11 PF08241.12 ORY03753.1 - 0.0049 17.5 0.1 0.011 16.3 0.1 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY03753.1 - 0.005 16.6 0.0 0.01 15.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY03753.1 - 0.0078 16.9 0.0 0.015 16.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.6 ORY03753.1 - 0.081 14.0 0.0 0.19 12.8 0.0 1.7 1 1 1 2 2 2 0 Zinc-binding dehydrogenase Methyltransf_12 PF08242.12 ORY03753.1 - 0.12 13.2 0.0 0.23 12.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Sugar_tr PF00083.24 ORY03754.1 - 1.9e-74 251.2 17.1 2.1e-74 251.0 17.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY03754.1 - 1.3e-25 90.1 20.7 1.3e-25 90.1 20.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF5504 PF17608.2 ORY03754.1 - 0.0098 16.0 7.5 2.2 8.4 1.3 3.4 3 1 0 3 3 3 2 Family of unknown function (DUF5504) SMP_LBD PF17047.5 ORY03755.1 - 0.12 11.9 0.3 6.6 6.2 0.1 2.2 1 1 1 2 2 2 0 Synaptotagmin-like mitochondrial-lipid-binding domain TssN PF17555.2 ORY03755.1 - 0.14 11.5 5.2 0.043 13.2 2.2 1.6 2 0 0 2 2 2 0 Type VI secretion system, TssN DUF423 PF04241.15 ORY03755.1 - 0.19 11.9 4.7 3.7 7.8 2.2 3.3 2 1 0 2 2 2 0 Protein of unknown function (DUF423) Abhydrolase_6 PF12697.7 ORY03757.1 - 0.0022 18.6 1.4 0.0022 18.6 1.4 2.6 1 1 0 2 2 2 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.7 ORY03757.1 - 0.01 14.8 0.5 0.025 13.5 0.5 1.5 1 1 0 1 1 1 0 Chlorophyllase enzyme Abhydrolase_1 PF00561.20 ORY03757.1 - 0.026 14.1 0.3 0.15 11.6 0.3 2.1 2 1 0 2 2 2 0 alpha/beta hydrolase fold MFS_1 PF07690.16 ORY03758.1 - 2.2e-37 128.8 25.4 2.2e-37 128.8 25.4 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily DNA_pol_A_exo1 PF01612.20 ORY03760.1 - 0.00027 20.7 0.0 0.0018 18.0 0.0 2.1 2 0 0 2 2 2 1 3'-5' exonuclease PSI PF01437.25 ORY03760.1 - 0.086 13.4 1.5 0.17 12.4 1.5 1.5 1 1 0 1 1 1 0 Plexin repeat ABC_membrane PF00664.23 ORY03827.1 - 2e-39 135.9 13.0 2.9e-39 135.4 13.0 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 ORY03827.1 - 7.4e-36 123.7 0.0 1.2e-35 123.0 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 ORY03827.1 - 3.2e-07 30.0 1.1 0.011 15.2 0.1 2.7 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 ORY03827.1 - 3.8e-05 22.7 0.3 0.0073 15.2 0.1 2.1 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_29 PF13555.6 ORY03827.1 - 0.00015 21.4 0.0 0.00042 20.0 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 ORY03827.1 - 0.00034 20.5 0.0 0.00048 19.9 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 ORY03827.1 - 0.00056 20.5 0.2 0.0012 19.4 0.2 1.4 1 0 0 1 1 1 1 AAA domain AAA_21 PF13304.6 ORY03827.1 - 0.00058 19.8 0.1 0.0092 15.8 0.0 2.1 1 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 ORY03827.1 - 0.00069 19.5 0.7 0.0063 16.4 0.0 2.7 3 0 0 3 3 3 1 RsgA GTPase AAA_22 PF13401.6 ORY03827.1 - 0.0017 18.7 0.1 0.012 15.8 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ORY03827.1 - 0.0019 18.6 0.1 0.0055 17.1 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 ORY03827.1 - 0.0059 16.3 0.2 0.046 13.4 0.2 2.2 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 ORY03827.1 - 0.035 14.5 0.1 1.7 9.1 0.1 2.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 ORY03827.1 - 0.057 12.9 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_18 PF13238.6 ORY03827.1 - 0.058 14.0 0.0 0.14 12.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 ORY03827.1 - 0.058 13.6 0.1 0.71 10.2 0.1 2.5 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.6 ORY03827.1 - 0.094 12.9 0.0 0.23 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 ORY03827.1 - 0.12 11.9 0.1 0.73 9.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain FSH1 PF03959.13 ORY03828.1 - 8.2e-27 94.2 0.0 9.6e-27 94.0 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) DUF3530 PF12048.8 ORY03828.1 - 0.16 11.4 0.0 0.22 10.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) adh_short_C2 PF13561.6 ORY03829.1 - 7e-59 199.2 2.7 8.2e-59 199.0 2.7 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY03829.1 - 4.9e-52 176.2 1.2 6.2e-52 175.9 1.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORY03829.1 - 4.8e-13 49.4 0.4 8.8e-13 48.6 0.4 1.3 1 0 0 1 1 1 1 KR domain DUF2620 PF10941.8 ORY03829.1 - 0.015 15.5 1.6 0.028 14.6 0.8 2.0 2 0 0 2 2 2 0 Protein of unknown function DUF2620 Sacchrp_dh_NADP PF03435.18 ORY03829.1 - 0.02 15.1 0.1 0.034 14.4 0.1 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain DUF1776 PF08643.10 ORY03829.1 - 0.026 13.9 0.0 0.04 13.3 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) THF_DHG_CYH_C PF02882.19 ORY03829.1 - 0.18 11.1 1.6 1 8.6 0.3 2.5 2 1 1 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain adh_short PF00106.25 ORY03830.1 - 1.9e-39 135.2 0.4 2.6e-39 134.7 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY03830.1 - 2.9e-30 105.6 0.1 3.7e-30 105.2 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY03830.1 - 3.9e-07 30.2 4.5 6.3e-06 26.2 4.5 2.1 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 ORY03830.1 - 0.0003 20.3 0.1 0.0011 18.5 0.1 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_2 PF03446.15 ORY03830.1 - 0.0093 16.1 0.0 0.042 14.0 0.0 2.0 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3Beta_HSD PF01073.19 ORY03830.1 - 0.015 14.3 0.0 0.021 13.8 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family 2-Hacid_dh_C PF02826.19 ORY03830.1 - 0.043 13.2 0.0 0.12 11.7 0.0 1.7 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.17 ORY03830.1 - 0.045 12.9 0.0 0.068 12.3 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain 3HCDH_N PF02737.18 ORY03830.1 - 0.11 12.3 2.9 0.94 9.3 2.9 2.2 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ketoacyl-synt PF00109.26 ORY03831.1 - 1.4e-66 224.6 0.1 3.6e-66 223.3 0.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 ORY03831.1 - 1.4e-58 197.8 0.7 7.6e-58 195.4 0.2 2.4 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.21 ORY03831.1 - 3.1e-43 148.5 0.0 6.5e-43 147.4 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 ORY03831.1 - 2.8e-36 125.3 0.0 5.2e-36 124.4 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 ORY03831.1 - 9e-32 109.6 0.0 4.4e-31 107.4 0.0 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.25 ORY03831.1 - 5.8e-18 65.0 1.3 2.5e-16 59.7 0.2 2.4 2 0 0 2 2 2 1 short chain dehydrogenase KAsynt_C_assoc PF16197.5 ORY03831.1 - 1.6e-15 57.5 0.0 4.6e-15 56.1 0.0 1.9 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension adh_short_C2 PF13561.6 ORY03831.1 - 2.2e-12 47.0 1.5 1.1e-11 44.8 0.1 2.4 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase PP-binding PF00550.25 ORY03831.1 - 6.6e-07 29.6 0.0 1.9e-06 28.1 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.23 ORY03831.1 - 1.9e-05 24.1 1.2 4.5e-05 22.9 1.2 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain Epimerase PF01370.21 ORY03831.1 - 0.00016 21.2 0.1 0.0014 18.2 0.0 2.3 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family ACP_syn_III PF08545.10 ORY03831.1 - 0.0062 16.4 0.9 0.02 14.7 0.9 2.0 1 1 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ADH_N PF08240.12 ORY03831.1 - 0.093 12.6 0.1 0.3 11.0 0.1 1.9 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain Polysacc_synt_2 PF02719.15 ORY03831.1 - 0.12 11.5 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 3HCDH PF00725.22 ORY03832.1 - 2.9e-14 53.4 0.1 1.1e-13 51.6 0.1 2.1 3 0 0 3 3 3 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Arylesterase PF01731.20 ORY03832.1 - 0.0005 20.2 0.0 2 8.7 0.0 3.6 4 0 0 4 4 4 2 Arylesterase NHL PF01436.21 ORY03832.1 - 0.00064 19.6 0.0 2.3 8.4 0.0 4.0 4 0 0 4 4 4 1 NHL repeat SGL PF08450.12 ORY03832.1 - 0.0058 16.2 0.0 0.12 11.9 0.0 2.4 2 1 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region 3HCDH_N PF02737.18 ORY03832.1 - 0.018 14.9 0.0 0.029 14.3 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ldl_recept_b PF00058.17 ORY03832.1 - 0.018 15.5 0.3 6.6 7.3 0.0 4.4 6 0 0 6 6 6 0 Low-density lipoprotein receptor repeat class B Str_synth PF03088.16 ORY03832.1 - 0.019 15.1 0.0 0.066 13.3 0.0 1.9 1 0 0 1 1 1 0 Strictosidine synthase INCENP_ARK-bind PF03941.15 ORY03833.1 - 2.2e-17 62.7 2.3 2.2e-17 62.7 2.3 2.5 2 0 0 2 2 2 1 Inner centromere protein, ARK binding region Acyl-CoA_dh_1 PF00441.24 ORY03834.1 - 2.2e-31 109.1 3.1 3.9e-31 108.3 3.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 ORY03834.1 - 4.3e-22 78.9 0.2 1e-21 77.7 0.1 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 ORY03834.1 - 2.6e-20 72.4 0.0 4.5e-20 71.7 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 ORY03834.1 - 9e-18 64.8 3.3 8.2e-17 61.7 1.1 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Tam41_Mmp37 PF09139.11 ORY03835.1 - 1.7e-118 395.8 0.0 2e-118 395.5 0.0 1.1 1 0 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial BIR PF00653.21 ORY03836.1 - 4.3e-46 155.5 1.2 3.2e-22 79.0 0.1 2.4 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain Peptidase_S64 PF08192.11 ORY03836.1 - 0.36 9.3 12.0 0.53 8.7 12.0 1.1 1 0 0 1 1 1 0 Peptidase family S64 COG5 PF10392.9 ORY03837.1 - 0.0018 18.5 0.1 0.0038 17.4 0.1 1.6 1 0 0 1 1 1 1 Golgi transport complex subunit 5 PARP PF00644.20 ORY03838.1 - 2.5e-09 37.0 0.1 5.6e-09 35.9 0.1 1.5 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain UQ_con PF00179.26 ORY03838.1 - 3.7e-07 29.9 0.0 7.2e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme GEN1_C PF18380.1 ORY03839.1 - 4.8e-28 98.1 0.2 4.8e-28 98.1 0.2 2.7 3 0 0 3 3 3 1 Holliday junction resolvase Gen1 C-terminal domain XPG_I PF00867.18 ORY03839.1 - 4e-23 81.6 0.0 7.5e-23 80.7 0.0 1.4 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 ORY03839.1 - 3.2e-10 40.4 0.0 6.4e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.7 ORY03839.1 - 0.079 12.4 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 XPG domain containing AT_hook PF02178.19 ORY03840.1 - 0.03 14.2 13.5 0.98 9.5 0.9 3.4 2 0 0 2 2 2 0 AT hook motif Peptidase_M24 PF00557.24 ORY03842.1 - 3e-52 177.4 0.0 5.1e-52 176.6 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 ORY03842.1 - 4.5e-40 136.2 0.0 8e-40 135.4 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain SIR2 PF02146.17 ORY03843.1 - 4.4e-40 137.5 0.0 8.6e-40 136.5 0.0 1.5 1 1 0 1 1 1 1 Sir2 family Zn_clus PF00172.18 ORY03844.1 - 2.4e-09 37.2 12.5 3.6e-09 36.6 12.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ORY03844.1 - 1.7e-07 30.6 4.5 3.3e-07 29.6 0.5 3.0 2 1 0 2 2 2 1 Fungal specific transcription factor domain TFIIA PF03153.13 ORY03844.1 - 3.1 7.7 25.7 0.2 11.6 15.5 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit EAP30 PF04157.16 ORY03844.1 - 9.8 5.4 9.2 40 3.4 9.1 2.0 2 0 0 2 2 2 0 EAP30/Vps36 family Copper-fist PF00649.18 ORY03845.1 - 9.2e-21 73.1 1.4 9.2e-21 73.1 1.4 2.0 2 0 0 2 2 2 1 Copper fist DNA binding domain Ank_2 PF12796.7 ORY03847.1 - 4.9e-07 30.3 0.0 5.5e-07 30.1 0.0 1.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ORY03847.1 - 0.00064 20.0 0.0 0.78 10.5 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 ORY03847.1 - 0.0013 19.2 0.0 0.0015 19.0 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 ORY03847.1 - 0.004 17.4 0.0 0.54 10.7 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 ORY03847.1 - 0.019 15.4 0.0 3.2 8.4 0.0 2.1 2 0 0 2 2 2 0 Ankyrin repeat WW PF00397.26 ORY03848.1 - 0.00027 21.0 0.5 0.00042 20.4 0.5 1.3 1 0 0 1 1 1 1 WW domain Pkinase PF00069.25 ORY03849.1 - 8.7e-63 212.1 0.0 1.2e-62 211.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY03849.1 - 2.4e-32 112.2 0.0 3.3e-32 111.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY03849.1 - 2.3e-05 23.9 0.0 3.7e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 ORY03849.1 - 0.00041 19.2 0.1 0.0011 17.8 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 ORY03849.1 - 0.00054 19.4 0.3 0.0012 18.2 0.3 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 ORY03849.1 - 0.0051 16.8 1.8 0.012 15.6 0.2 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Endonuc_Holl PF10107.9 ORY03849.1 - 0.16 11.8 0.1 0.45 10.3 0.0 1.7 2 0 0 2 2 2 0 Endonuclease related to archaeal Holliday junction resolvase Haspin_kinase PF12330.8 ORY03849.1 - 0.21 10.5 0.0 0.32 9.9 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain 5_nucleotid_C PF02872.18 ORY03852.1 - 3.4e-38 131.3 0.0 5.7e-38 130.6 0.0 1.3 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 ORY03852.1 - 0.00033 21.2 0.1 0.00055 20.5 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase ING PF12998.7 ORY03853.1 - 4.9e-06 27.1 0.4 0.00017 22.1 0.4 2.4 1 1 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 ORY03853.1 - 8.5e-05 22.4 8.8 0.00014 21.7 8.8 1.3 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 ORY03853.1 - 0.15 12.4 2.1 0.3 11.4 2.1 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain Aldolase_II PF00596.21 ORY03855.1 - 1.4e-48 165.3 0.0 1.8e-48 165.0 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain His_Phos_1 PF00300.22 ORY03856.1 - 6.9e-05 22.6 0.8 4.4 7.0 0.1 3.8 4 0 0 4 4 4 3 Histidine phosphatase superfamily (branch 1) PSP1 PF04468.12 ORY03857.1 - 1.2e-21 76.7 0.6 2.1e-21 76.0 0.6 1.4 1 0 0 1 1 1 1 PSP1 C-terminal conserved region MARVEL PF01284.23 ORY03861.1 - 4.5e-29 101.3 13.9 5.4e-29 101.1 13.9 1.0 1 0 0 1 1 1 1 Membrane-associating domain Alpha-amylase_N PF02903.14 ORY03863.1 - 0.026 14.7 0.0 0.048 13.8 0.0 1.4 1 0 0 1 1 1 0 Alpha amylase, N-terminal ig-like domain Gastrin PF00918.17 ORY03863.1 - 0.08 13.9 2.1 0.1 13.6 0.7 1.8 2 0 0 2 2 2 0 Gastrin/cholecystokinin family MMR1 PF08505.10 ORY03863.1 - 0.52 10.6 5.3 0.64 10.3 4.9 1.4 1 1 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein SurA_N_2 PF13623.6 ORY03863.1 - 7 6.5 9.6 0.64 9.9 2.7 2.1 1 1 1 2 2 2 0 SurA N-terminal domain Ribosomal_L15e PF00827.17 ORY03864.1 - 3.7e-90 300.8 11.0 4.5e-90 300.5 11.0 1.0 1 0 0 1 1 1 1 Ribosomal L15 DnaJ PF00226.31 ORY03865.1 - 5.3e-24 84.1 0.9 6.3e-24 83.9 0.9 1.1 1 0 0 1 1 1 1 DnaJ domain Cellulase PF00150.18 ORY03921.1 - 1.3e-49 169.1 5.0 1.7e-49 168.7 5.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.18 ORY03921.1 - 1.9e-13 50.1 8.3 1.9e-13 50.1 8.3 2.8 3 0 0 3 3 3 1 Fungal cellulose binding domain sCache_3_3 PF17202.4 ORY03921.1 - 0.14 12.6 0.0 0.27 11.7 0.0 1.5 1 0 0 1 1 1 0 Single cache domain 3 Syntaxin-6_N PF09177.11 ORY03922.1 - 0.002 18.7 4.4 0.43 11.2 0.3 3.4 2 1 1 3 3 3 1 Syntaxin 6, N-terminal Myosin_tail_1 PF01576.19 ORY03922.1 - 0.012 13.4 4.3 0.81 7.4 0.1 2.2 2 0 0 2 2 2 0 Myosin tail CENP-F_leu_zip PF10473.9 ORY03922.1 - 0.022 14.8 3.7 1.3 9.1 0.0 3.4 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3138 PF11336.8 ORY03922.1 - 0.044 12.4 0.2 0.044 12.4 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) DASH_Dad2 PF08654.10 ORY03922.1 - 0.061 13.8 0.6 0.25 11.8 0.1 2.4 2 0 0 2 2 2 0 DASH complex subunit Dad2 DivIC PF04977.15 ORY03922.1 - 0.07 12.9 3.6 0.97 9.2 0.0 3.3 3 0 0 3 3 3 0 Septum formation initiator Ax_dynein_light PF10211.9 ORY03922.1 - 0.11 12.4 8.2 1.2 9.1 4.3 2.9 2 1 1 3 3 3 0 Axonemal dynein light chain FlaC_arch PF05377.11 ORY03922.1 - 0.16 12.4 3.7 9.2 6.7 0.0 3.9 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) TMPIT PF07851.13 ORY03922.1 - 0.24 10.6 0.3 1.3 8.2 0.1 1.9 2 0 0 2 2 2 0 TMPIT-like protein Cob_adeno_trans PF01923.18 ORY03922.1 - 0.3 11.2 5.9 0.57 10.3 0.5 2.9 3 0 0 3 3 3 0 Cobalamin adenosyltransferase DHR10 PF18595.1 ORY03922.1 - 0.3 11.1 11.2 0.45 10.6 0.1 3.3 3 1 1 4 4 4 0 Designed helical repeat protein 10 domain DUF1515 PF07439.11 ORY03922.1 - 0.38 10.8 3.6 0.19 11.8 0.4 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1515) Filament PF00038.21 ORY03922.1 - 0.49 9.9 7.8 0.37 10.3 1.4 2.5 3 0 0 3 3 3 0 Intermediate filament protein Med9 PF07544.13 ORY03922.1 - 0.95 9.6 4.6 4.4 7.5 2.0 2.8 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Laminin_II PF06009.12 ORY03922.1 - 1.2 9.1 6.7 10 6.1 0.1 3.0 3 0 0 3 3 3 0 Laminin Domain II BLOC1_2 PF10046.9 ORY03922.1 - 1.5 9.2 8.9 1.2 9.5 0.1 3.8 4 0 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Seryl_tRNA_N PF02403.22 ORY03922.1 - 2.2 8.5 8.3 5.3 7.3 1.3 2.8 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF4407 PF14362.6 ORY03923.1 - 0.0048 16.3 0.6 0.0062 15.9 0.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) MRP-S26 PF14943.6 ORY03923.1 - 0.34 10.8 8.0 0.067 13.1 3.9 1.8 2 0 0 2 2 2 0 Mitochondrial ribosome subunit S26 Septin PF00735.18 ORY03924.1 - 2e-111 371.8 0.2 2.5e-111 371.5 0.2 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 ORY03924.1 - 6.3e-08 32.7 0.0 1.1e-07 32.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 ORY03924.1 - 4.5e-06 26.2 0.0 8e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 AIG1 family RsgA_GTPase PF03193.16 ORY03924.1 - 4.2e-05 23.5 0.1 0.00028 20.8 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 ORY03924.1 - 0.00013 21.6 0.6 0.013 15.1 0.1 2.4 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 ORY03924.1 - 0.00095 19.3 0.2 0.69 9.9 0.1 2.5 1 1 1 2 2 2 2 Dynamin family NB-ARC PF00931.22 ORY03924.1 - 0.0029 16.8 0.1 0.0051 16.0 0.1 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_7 PF12775.7 ORY03924.1 - 0.0036 16.8 0.1 0.013 15.0 0.0 1.9 2 0 0 2 2 2 1 P-loop containing dynein motor region ABC_tran PF00005.27 ORY03924.1 - 0.0098 16.4 0.4 0.016 15.8 0.2 1.7 1 1 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 ORY03924.1 - 0.01 16.2 0.0 0.019 15.3 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 ORY03924.1 - 0.021 15.1 0.1 0.041 14.2 0.1 1.6 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 ORY03924.1 - 0.05 13.0 0.0 0.084 12.2 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Gtr1_RagA PF04670.12 ORY03924.1 - 0.062 12.6 0.1 0.61 9.4 0.0 2.1 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region Roc PF08477.13 ORY03924.1 - 0.068 13.4 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 ORY03924.1 - 0.096 11.8 0.5 0.18 11.0 0.5 1.7 1 1 0 1 1 1 0 G-protein alpha subunit T2SSE PF00437.20 ORY03924.1 - 0.14 11.2 0.0 0.3 10.1 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.6 ORY03924.1 - 0.18 11.6 0.0 0.34 10.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Ribosomal_L32p PF01783.23 ORY03925.1 - 2.6e-12 46.8 1.4 2.6e-12 46.8 1.4 2.5 2 1 0 2 2 2 1 Ribosomal L32p protein family DUF2913 PF11140.8 ORY03925.1 - 0.1 12.3 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2913) GRAB PF10375.9 ORY03926.1 - 4e-08 32.8 0.1 8.5e-08 31.8 0.1 1.6 1 0 0 1 1 1 1 GRIP-related Arf-binding domain Tup_N PF08581.10 ORY03926.1 - 0.0072 16.6 1.4 0.0072 16.6 1.4 5.0 4 1 0 4 4 4 1 Tup N-terminal COG2 PF06148.11 ORY03926.1 - 0.05 13.7 0.6 0.05 13.7 0.6 4.4 2 1 1 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF641 PF04859.12 ORY03926.1 - 0.07 13.5 29.2 1.8 8.9 2.2 3.8 3 1 0 3 3 3 0 Plant protein of unknown function (DUF641) BST2 PF16716.5 ORY03926.1 - 0.096 13.3 41.4 0.11 13.1 11.7 4.7 2 2 2 4 4 4 0 Bone marrow stromal antigen 2 DUF4407 PF14362.6 ORY03926.1 - 0.28 10.5 42.2 0.93 8.8 16.6 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) Golgin_A5 PF09787.9 ORY03926.1 - 0.3 10.5 49.2 11 5.4 29.2 3.2 1 1 1 2 2 2 0 Golgin subfamily A member 5 ATG16 PF08614.11 ORY03926.1 - 0.37 11.0 59.8 7.5 6.7 9.4 4.0 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) TPR_MLP1_2 PF07926.12 ORY03926.1 - 0.68 10.0 64.2 5.3 7.1 9.4 4.6 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein FAM184 PF15665.5 ORY03926.1 - 0.77 9.5 48.3 1.2 8.9 24.9 2.5 1 1 1 2 2 2 0 Family with sequence similarity 184, A and B COMM_domain PF07258.14 ORY03926.1 - 0.83 9.8 4.0 1.3 9.2 0.9 2.6 2 0 0 2 2 2 0 COMM domain Shugoshin_N PF07558.11 ORY03926.1 - 1.5 8.7 8.0 3 7.8 3.1 2.7 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region Atg14 PF10186.9 ORY03926.1 - 1.7 7.7 43.4 0.23 10.5 18.9 3.1 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 GBR2_CC PF18455.1 ORY03926.1 - 2 8.6 5.0 0.99 9.6 0.4 2.8 3 0 0 3 3 3 0 Gamma-aminobutyric acid type B receptor subunit 2 coiled-coil domain Fib_alpha PF08702.10 ORY03926.1 - 2.2 8.5 26.9 2.1 8.5 8.3 4.0 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family ApoO PF09769.9 ORY03926.1 - 2.8 7.9 13.4 5.2 7.0 0.1 4.0 2 1 1 4 4 4 0 Apolipoprotein O DUF1664 PF07889.12 ORY03926.1 - 2.9 8.0 22.3 0.71 9.9 1.1 4.0 2 2 3 5 5 5 0 Protein of unknown function (DUF1664) DUF1515 PF07439.11 ORY03926.1 - 2.9 7.9 17.3 2.9 7.9 0.4 4.0 3 1 1 4 4 4 0 Protein of unknown function (DUF1515) Filament PF00038.21 ORY03926.1 - 3 7.4 49.0 1.9 8.0 8.9 2.8 1 1 1 2 2 2 0 Intermediate filament protein HOOK PF05622.12 ORY03926.1 - 7.4 4.6 50.6 0.55 8.3 21.6 3.2 1 1 1 2 2 2 0 HOOK protein KxDL PF10241.9 ORY03926.1 - 8 6.8 29.3 0.16 12.3 4.9 4.7 4 1 1 5 5 4 0 Uncharacterized conserved protein XhlA PF10779.9 ORY03926.1 - 8.2 6.7 27.2 0.33 11.2 0.4 5.6 4 1 1 5 5 5 0 Haemolysin XhlA Zw10 PF06248.13 ORY03926.1 - 8.2 4.9 20.8 0.91 8.0 15.0 1.7 1 1 1 2 2 2 0 Centromere/kinetochore Zw10 Cnn_1N PF07989.11 ORY03926.1 - 8.5 6.6 37.2 1.4 9.2 5.9 5.5 3 2 1 4 4 4 0 Centrosomin N-terminal motif 1 DUF1045 PF06299.12 ORY03926.1 - 8.8 6.3 12.8 0.48 10.4 6.7 2.0 2 0 0 2 2 1 0 Protein of unknown function (DUF1045) Catalase PF00199.19 ORY03927.1 - 1.1e-08 34.6 0.0 6.6e-07 28.8 0.0 2.1 2 0 0 2 2 2 2 Catalase Peptidase_S41 PF03572.18 ORY03927.1 - 0.17 11.4 0.0 0.26 10.8 0.0 1.2 1 0 0 1 1 1 0 Peptidase family S41 Zn_clus PF00172.18 ORY03928.1 - 0.0026 17.8 6.1 0.0056 16.8 6.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Thiolase_N PF00108.23 ORY03930.1 - 6.2e-17 61.8 0.0 8.7e-16 58.1 0.0 2.3 2 1 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 ORY03930.1 - 1.5e-10 40.8 3.4 2.4e-10 40.1 1.1 2.5 2 1 1 3 3 3 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 ORY03930.1 - 2.3e-05 24.1 0.1 5.4e-05 22.9 0.0 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 ORY03930.1 - 3.9e-05 23.4 0.1 0.0006 19.6 0.0 2.4 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III SpoVAD PF07451.11 ORY03930.1 - 0.069 11.8 0.3 0.68 8.6 0.1 2.2 2 0 0 2 2 2 0 Stage V sporulation protein AD (SpoVAD) Ketoacyl-synt_C PF02801.22 ORY03930.1 - 0.085 12.9 2.6 0.46 10.5 0.5 3.0 3 1 0 3 3 3 0 Beta-ketoacyl synthase, C-terminal domain DUF1996 PF09362.10 ORY03931.1 - 2e-83 279.9 1.2 2.5e-83 279.7 1.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Arm_2 PF04826.13 ORY03932.1 - 0.015 14.8 0.0 0.016 14.7 0.0 1.0 1 0 0 1 1 1 0 Armadillo-like 60KD_IMP PF02096.20 ORY03933.1 - 3.1e-09 36.9 0.0 4.1e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 60Kd inner membrane protein ALG11_N PF15924.5 ORY03934.1 - 4.2e-84 281.8 0.0 5.6e-84 281.4 0.0 1.1 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 ORY03934.1 - 5e-20 71.7 0.0 8.5e-20 71.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 ORY03934.1 - 1.1e-09 38.9 0.0 3.6e-09 37.1 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 ORY03934.1 - 7.6e-05 22.8 0.5 0.00018 21.6 0.5 1.6 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Prok-JAB PF14464.6 ORY03934.1 - 0.87 9.4 3.5 1.3 8.8 1.7 2.1 2 0 0 2 2 2 0 Prokaryotic homologs of the JAB domain DENN PF02141.21 ORY03936.1 - 1.3e-57 194.8 0.1 2.3e-57 194.0 0.1 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 ORY03936.1 - 9.8e-16 58.3 0.1 2.8e-15 56.8 0.1 1.9 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.19 ORY03936.1 - 7.7e-15 54.6 1.1 1.8e-14 53.4 1.1 1.7 1 0 0 1 1 1 1 dDENN domain C1_2 PF03107.16 ORY03936.1 - 0.00075 19.8 5.2 0.0017 18.6 5.2 1.6 1 0 0 1 1 1 1 C1 domain C1_1 PF00130.22 ORY03936.1 - 0.043 13.7 9.3 0.1 12.5 9.3 1.6 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD PF00628.29 ORY03936.1 - 0.24 11.3 7.7 0.064 13.2 3.9 1.9 1 1 1 2 2 2 0 PHD-finger Zf_RING PF16744.5 ORY03936.1 - 0.36 11.0 5.1 0.75 9.9 5.1 1.5 1 0 0 1 1 1 0 KIAA1045 RING finger DUF974 PF06159.13 ORY03937.1 - 2.7e-76 256.7 0.0 3.2e-76 256.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF974) SET PF00856.28 ORY03938.1 - 4.4e-15 56.5 0.0 4.6e-13 49.9 0.0 2.1 1 1 0 1 1 1 1 SET domain SAF PF08666.12 ORY03938.1 - 0.099 13.3 0.1 2.4 8.8 0.0 2.4 2 1 0 2 2 2 0 SAF domain DUF2408 PF10303.9 ORY03939.1 - 5.6e-46 156.5 8.8 4.2e-28 98.6 0.8 6.0 3 2 1 4 4 4 4 Protein of unknown function (DUF2408) AAA_13 PF13166.6 ORY03939.1 - 0.07 11.8 0.0 0.1 11.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain CCDC92 PF14916.6 ORY03939.1 - 0.075 12.8 0.1 0.35 10.7 0.0 2.1 2 0 0 2 2 2 0 Coiled-coil domain of unknown function EF-hand_13 PF17958.1 ORY03939.1 - 0.12 12.2 0.0 0.3 10.9 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain KorB PF08535.10 ORY03939.1 - 0.15 12.1 0.1 0.46 10.5 0.1 1.8 1 0 0 1 1 1 0 KorB domain SRP68 PF16969.5 ORY03939.1 - 0.17 10.8 1.9 0.34 9.9 0.3 1.9 1 1 0 2 2 2 0 RNA-binding signal recognition particle 68 Ribosomal_60s PF00428.19 ORY03940.1 - 7.3e-25 87.4 12.2 9e-25 87.1 12.2 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Cytomega_UL84 PF06284.11 ORY03940.1 - 0.44 8.9 1.0 0.54 8.7 1.0 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein DUF3824 PF12868.7 ORY03940.1 - 3.5 8.3 4.8 5.4 7.7 4.8 1.2 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) Cyclase PF04199.13 ORY03941.1 - 7.7e-13 48.9 0.0 9.9e-13 48.5 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase Sugar_tr PF00083.24 ORY03942.1 - 3.3e-74 250.4 22.4 3.8e-74 250.2 22.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY03942.1 - 1.4e-18 66.9 49.7 5.3e-15 55.2 23.3 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2070 PF09843.9 ORY03942.1 - 0.0073 14.7 0.5 0.014 13.7 0.5 1.4 1 0 0 1 1 1 1 Predicted membrane protein (DUF2070) RseC_MucC PF04246.12 ORY03943.1 - 0.25 11.3 1.5 1.2 9.0 0.2 2.1 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC DUF4203 PF13886.6 ORY03943.1 - 0.4 10.3 3.8 1.3 8.6 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4203) Shugoshin_N PF07558.11 ORY03944.1 - 3.1e-17 62.1 7.0 6.9e-17 61.0 7.0 1.6 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region Shugoshin_C PF07557.11 ORY03944.1 - 3.3e-12 46.0 5.5 3.3e-12 46.0 5.5 2.8 3 0 0 3 3 3 1 Shugoshin C terminus DUF3915 PF13054.6 ORY03944.1 - 0.058 13.4 3.6 0.14 12.1 3.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Mod_r PF07200.13 ORY03944.1 - 0.067 13.3 3.0 0.069 13.2 1.0 2.0 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein HALZ PF02183.18 ORY03944.1 - 0.2 11.9 2.3 36 4.7 2.7 2.4 2 0 0 2 2 2 0 Homeobox associated leucine zipper GIT_CC PF16559.5 ORY03944.1 - 0.35 10.8 2.7 0.82 9.6 2.7 1.6 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor TMCO5 PF14992.6 ORY03944.1 - 4.6 6.7 10.7 0.061 12.9 2.9 1.7 2 0 0 2 2 2 0 TMCO5 family DASH_Dad2 PF08654.10 ORY03945.1 - 1.4e-33 115.3 0.2 1.7e-33 115.0 0.2 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad2 DASH_Duo1 PF08651.10 ORY03945.1 - 0.095 12.5 0.1 0.14 11.9 0.1 1.2 1 0 0 1 1 1 0 DASH complex subunit Duo1 PAX PF00292.18 ORY03945.1 - 0.16 11.9 0.0 0.8 9.6 0.1 1.9 1 1 0 1 1 1 0 'Paired box' domain PPI_Ypi1 PF07491.11 ORY03946.1 - 6e-24 83.6 4.8 6e-24 83.6 4.8 2.2 2 1 0 2 2 2 1 Protein phosphatase inhibitor SURF2 PF05477.11 ORY03946.1 - 0.0077 15.9 2.8 0.0083 15.8 2.8 1.1 1 0 0 1 1 1 1 Surfeit locus protein 2 (SURF2) DUF4692 PF15763.5 ORY03946.1 - 0.053 14.0 1.4 0.095 13.2 1.4 1.4 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) CDC45 PF02724.14 ORY03946.1 - 0.52 8.5 5.9 0.55 8.5 5.9 1.0 1 0 0 1 1 1 0 CDC45-like protein SelP_N PF04592.14 ORY03946.1 - 0.68 9.3 4.6 0.8 9.1 4.6 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Cuticle_2 PF08184.11 ORY03947.1 - 0.42 10.7 4.0 0.38 10.8 1.7 2.1 2 0 0 2 2 2 0 Cuticle protein 7 isoform family Queuosine_synth PF02547.15 ORY03947.1 - 1.1 8.3 7.1 0.17 11.0 1.1 2.1 1 1 0 2 2 2 0 Queuosine biosynthesis protein adh_short PF00106.25 ORY03950.1 - 3.5e-30 104.9 0.0 5.6e-30 104.3 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY03950.1 - 1.8e-20 73.5 0.1 2.3e-20 73.2 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY03950.1 - 0.0036 17.2 0.1 0.25 11.2 0.0 2.5 2 1 0 2 2 2 1 KR domain Eno-Rase_NADH_b PF12242.8 ORY03950.1 - 0.02 14.7 0.0 0.043 13.6 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Ldh_1_N PF00056.23 ORY03950.1 - 0.082 13.0 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain ThiC-associated PF13667.6 ORY03950.1 - 0.14 12.0 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 ThiC-associated domain EMP24_GP25L PF01105.24 ORY03951.1 - 6.3e-50 169.6 0.0 7.2e-50 169.4 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD F-box PF00646.33 ORY03952.1 - 0.002 18.0 0.2 0.0056 16.5 0.2 1.8 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 ORY03952.1 - 0.02 14.8 0.7 0.05 13.5 0.0 2.1 3 0 0 3 3 3 0 F-box CbiG_mid PF11761.8 ORY03952.1 - 0.055 13.6 0.0 0.19 11.9 0.0 1.9 1 0 0 1 1 1 0 Cobalamin biosynthesis central region Cyclase PF04199.13 ORY03953.1 - 3.1e-17 63.1 0.4 1.1e-16 61.3 0.2 1.7 1 1 1 2 2 2 1 Putative cyclase Sugar_tr PF00083.24 ORY03954.1 - 3.7e-74 250.2 20.4 4.5e-74 250.0 20.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY03954.1 - 4.2e-18 65.4 26.1 4.2e-18 65.4 26.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily CIAPIN1 PF05093.13 ORY03956.1 - 6.7e-44 148.5 4.2 1.1e-43 147.7 4.2 1.4 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DRE2_N PF16803.5 ORY03956.1 - 9.5e-39 132.6 0.0 1.3e-38 132.2 0.0 1.2 1 0 0 1 1 1 1 Fe-S cluster assembly protein DRE2 N-terminus DUF2240 PF09999.9 ORY03956.1 - 0.062 12.9 0.0 1.7 8.2 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2240) HABP4_PAI-RBP1 PF04774.15 ORY03957.1 - 0.75 10.6 9.4 2.9 8.7 9.4 1.9 1 1 0 1 1 1 0 Hyaluronan / mRNA binding family Nucleoporin_C PF03177.14 ORY03958.1 - 2.8e-134 449.1 8.6 3.7e-134 448.7 8.6 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.11 ORY03958.1 - 8e-40 136.9 0.0 1.1e-39 136.5 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Pkinase PF00069.25 ORY03959.1 - 1.4e-27 96.8 0.0 1.8e-27 96.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY03959.1 - 1.1e-14 54.4 0.0 1.4e-14 54.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORY03959.1 - 7.3e-07 28.3 0.0 1.1e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase SANT_DAMP1_like PF16282.5 ORY03960.1 - 9e-28 96.3 0.4 2.4e-27 95.0 0.4 1.8 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 BUD22 PF09073.10 ORY03960.1 - 0.006 16.0 25.1 0.015 14.6 25.1 1.6 1 0 0 1 1 1 1 BUD22 Myb_DNA-binding PF00249.31 ORY03960.1 - 0.062 13.5 0.0 0.28 11.4 0.1 2.1 2 0 0 2 2 2 0 Myb-like DNA-binding domain HTH_AraC PF00165.23 ORY03998.1 - 0.037 14.2 0.1 0.089 12.9 0.0 1.7 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix proteins, AraC family SPC25 PF06703.11 ORY03999.1 - 5.4e-57 192.1 0.1 6.4e-57 191.9 0.1 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) EMC3_TMCO1 PF01956.16 ORY04000.1 - 1.3e-57 194.3 1.0 1.6e-57 193.9 1.0 1.1 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like EI24 PF07264.11 ORY04000.1 - 0.02 15.1 0.0 0.039 14.2 0.0 1.4 1 1 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) zf-C2H2_4 PF13894.6 ORY04002.1 - 0.13 13.2 0.2 0.13 13.2 0.2 4.7 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2 PF00096.26 ORY04002.1 - 1.5 9.4 11.8 3 8.5 0.1 4.0 4 0 0 4 4 4 0 Zinc finger, C2H2 type Presenilin PF01080.17 ORY04002.1 - 1.5 7.5 3.4 2.7 6.7 3.4 1.4 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 ORY04002.1 - 3.7 5.7 6.9 5.7 5.1 6.9 1.2 1 0 0 1 1 1 0 CDC45-like protein STT3 PF02516.14 ORY04003.1 - 3.6e-144 481.3 38.0 2.6e-140 468.6 34.6 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit RNase_T PF00929.24 ORY04005.1 - 1.5e-06 28.9 0.0 4.5e-06 27.3 0.0 1.8 1 1 0 1 1 1 1 Exonuclease CDC45 PF02724.14 ORY04005.1 - 0.15 10.3 11.5 0.24 9.6 11.5 1.2 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.12 ORY04005.1 - 4.8 6.9 6.7 11 5.8 6.7 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RRP7 PF12923.7 ORY04005.1 - 4.9 7.3 16.9 0.35 11.0 8.0 3.0 3 1 0 3 3 3 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain Yippee-Mis18 PF03226.14 ORY04006.1 - 0.00066 19.9 0.0 0.036 14.3 0.1 2.4 1 1 1 2 2 2 2 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Tropomyosin_1 PF12718.7 ORY04006.1 - 4.4 7.4 8.1 4.9 7.3 0.6 2.7 2 0 0 2 2 2 0 Tropomyosin like Fibrillarin_2 PF10113.9 ORY04007.1 - 0.035 12.7 0.0 0.046 12.4 0.0 1.1 1 0 0 1 1 1 0 Fibrillarin-like archaeal protein UAA PF08449.11 ORY04009.1 - 9.9e-82 274.5 11.7 1.3e-81 274.1 11.7 1.0 1 0 0 1 1 1 1 UAA transporter family SLC35F PF06027.12 ORY04009.1 - 0.23 10.9 7.6 1.1 8.8 1.6 2.3 2 0 0 2 2 2 0 Solute carrier family 35 TssN PF17555.2 ORY04009.1 - 3 7.1 8.5 0.85 9.0 1.6 2.5 2 1 0 2 2 2 0 Type VI secretion system, TssN WD40 PF00400.32 ORY04010.1 - 3.7e-12 46.6 4.8 0.12 13.3 0.3 6.5 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY04010.1 - 0.015 15.5 0.1 3.5 8.0 0.0 3.6 4 2 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain AF-4 PF05110.13 ORY04010.1 - 0.24 9.4 0.6 0.34 9.0 0.6 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Ribosomal_L3 PF00297.22 ORY04011.1 - 8.3e-183 607.4 8.3 9.4e-183 607.3 8.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 FAD_binding_2 PF00890.24 ORY04012.1 - 3.1e-125 418.5 2.1 3.9e-125 418.2 2.1 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 ORY04012.1 - 3.4e-45 153.2 0.8 5.1e-45 152.6 0.8 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Thi4 PF01946.17 ORY04012.1 - 4.4e-05 22.8 0.2 0.018 14.3 0.1 2.5 2 0 0 2 2 2 2 Thi4 family Pyr_redox_2 PF07992.14 ORY04012.1 - 8.1e-05 22.0 0.3 0.036 13.3 0.0 2.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 ORY04012.1 - 0.00016 20.9 2.2 0.066 12.3 1.6 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_3 PF01494.19 ORY04012.1 - 0.0092 15.3 0.5 0.017 14.4 0.1 1.6 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 ORY04012.1 - 0.11 12.0 2.1 0.51 9.9 2.1 2.1 1 1 0 1 1 1 0 FAD dependent oxidoreductase AAA PF00004.29 ORY04014.1 - 6.2e-41 139.9 0.0 1.1e-40 139.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 ORY04014.1 - 5.9e-06 26.0 0.0 1.4e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 ORY04014.1 - 7.2e-05 23.1 0.0 0.0059 16.9 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 ORY04014.1 - 0.0001 22.3 0.1 0.00043 20.3 0.0 2.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 ORY04014.1 - 0.00017 21.7 0.0 0.00069 19.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 ORY04014.1 - 0.00056 20.3 0.1 0.012 16.1 0.0 2.2 1 1 0 2 2 2 1 AAA ATPase domain DUF815 PF05673.13 ORY04014.1 - 0.0014 17.9 0.0 0.0027 16.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 ORY04014.1 - 0.0079 15.9 0.0 0.016 15.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 ORY04014.1 - 0.024 14.9 0.0 0.063 13.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 ORY04014.1 - 0.029 13.9 0.0 0.097 12.2 0.0 1.9 1 1 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 ORY04014.1 - 0.04 14.3 0.0 0.16 12.4 0.0 2.0 2 0 0 2 2 2 0 RNA helicase AAA_30 PF13604.6 ORY04014.1 - 0.047 13.4 0.1 0.59 9.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 ORY04014.1 - 0.048 13.8 0.0 0.094 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 ORY04014.1 - 0.082 12.8 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 ORY04014.1 - 0.11 13.1 0.0 0.49 10.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 ORY04014.1 - 0.11 12.3 0.6 0.54 10.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 ORY04014.1 - 0.14 11.5 0.0 0.36 10.2 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Cpn60_TCP1 PF00118.24 ORY04015.1 - 2.7e-146 488.0 16.8 3.1e-146 487.8 16.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Lactamase_B PF00753.27 ORY04016.1 - 3.8e-13 49.9 4.7 5.4e-13 49.4 4.7 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 ORY04016.1 - 0.00016 21.2 0.2 0.00022 20.8 0.2 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_6 PF16661.5 ORY04016.1 - 0.011 15.2 0.9 3.9 6.9 0.1 2.6 3 0 0 3 3 3 0 Metallo-beta-lactamase superfamily domain PBP PF01161.20 ORY04017.1 - 0.13 12.6 0.0 0.32 11.3 0.0 1.7 1 1 0 1 1 1 0 Phosphatidylethanolamine-binding protein zf-BED PF02892.15 ORY04018.1 - 0.00041 20.3 15.0 0.013 15.5 0.6 3.5 3 0 0 3 3 3 2 BED zinc finger zf-C2H2 PF00096.26 ORY04018.1 - 0.0017 18.7 9.2 0.0018 18.6 1.6 3.1 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY04018.1 - 0.0069 17.1 1.5 0.0069 17.1 1.5 2.9 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_11 PF16622.5 ORY04018.1 - 0.083 12.7 0.5 0.37 10.6 0.5 2.2 1 0 0 1 1 1 0 zinc-finger C2H2-type zinc_ribbon_4 PF13717.6 ORY04018.1 - 0.71 9.9 3.9 0.83 9.6 0.2 2.3 2 0 0 2 2 2 0 zinc-ribbon domain PWWP PF00855.17 ORY04020.1 - 1.1e-15 57.9 0.2 1.1e-15 57.9 0.2 2.8 3 0 0 3 3 3 1 PWWP domain WD40 PF00400.32 ORY04021.1 - 5.8e-16 58.6 6.0 0.0067 17.3 0.3 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY04021.1 - 2.1e-06 27.9 0.2 0.018 15.3 0.1 4.0 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ORY04021.1 - 2.5e-05 23.2 1.0 7.6e-05 21.5 0.2 2.0 2 1 0 2 2 2 1 Nucleoporin Nup120/160 Ribosomal_L37 PF08561.10 ORY04023.1 - 5.2e-41 139.9 0.0 8e-41 139.3 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L37 Shisa PF13908.6 ORY04023.1 - 2.2 8.5 6.5 3.1 8.0 6.5 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF3818 PF12825.7 ORY04024.1 - 2e-131 438.0 4.4 3.8e-131 437.1 4.4 1.5 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 ORY04024.1 - 3e-39 134.0 1.7 7e-39 132.8 1.7 1.7 1 0 0 1 1 1 1 PX-associated PX PF00787.24 ORY04024.1 - 3.6e-12 46.3 0.1 2.6e-11 43.5 0.1 2.4 1 1 0 1 1 1 1 PX domain GFD1 PF17331.2 ORY04024.1 - 0.59 10.4 5.5 2.3 8.5 5.5 2.0 1 0 0 1 1 1 0 GFD1 mRNA transport factor DUF3546 PF12066.8 ORY04026.1 - 1.2e-31 109.1 8.7 1.2e-31 109.1 8.7 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3546) ARS2 PF04959.13 ORY04026.1 - 2.4e-12 47.6 0.4 2.4e-12 47.6 0.4 2.2 1 1 1 2 2 2 1 Arsenite-resistance protein 2 DUF4187 PF13821.6 ORY04026.1 - 1.3e-11 44.1 0.2 3.6e-11 42.7 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) Ribosomal_60s PF00428.19 ORY04026.1 - 0.19 12.3 6.2 23 5.6 4.1 2.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein TspO_MBR PF03073.15 ORY04027.1 - 6.2e-47 159.0 7.1 7.5e-47 158.8 7.1 1.1 1 0 0 1 1 1 1 TspO/MBR family CRISPR_Cas6 PF10040.9 ORY04027.1 - 0.13 12.9 0.0 0.25 12.0 0.0 1.6 1 1 0 1 1 1 0 CRISPR-associated endoribonuclease Cas6 BBP1_C PF15272.6 ORY04028.1 - 0.0064 16.3 1.1 0.012 15.5 1.1 1.4 1 0 0 1 1 1 1 Spindle pole body component BBP1, C-terminal YtxH PF12732.7 ORY04028.1 - 0.23 12.0 0.8 1.6 9.3 0.8 2.4 1 1 0 1 1 1 0 YtxH-like protein DUF3683 PF12447.8 ORY04028.1 - 0.58 10.3 2.7 3 8.0 0.1 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3683) SelP_N PF04592.14 ORY04028.1 - 0.61 9.4 16.4 1.6 8.1 16.4 1.8 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF5082 PF16888.5 ORY04028.1 - 1.2 9.4 4.8 2.3 8.5 3.6 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) Spc7 PF08317.11 ORY04028.1 - 1.6 7.6 9.9 2.2 7.1 9.9 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF948 PF06103.11 ORY04028.1 - 2 8.7 4.2 2.9 8.2 0.7 2.7 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Fib_alpha PF08702.10 ORY04028.1 - 2.3 8.4 3.9 4.4 7.5 3.4 1.6 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family THOC7 PF05615.13 ORY04028.1 - 3.3 8.0 11.4 6.7 7.0 7.9 2.3 1 1 1 2 2 2 0 Tho complex subunit 7 Cgr1 PF03879.14 ORY04029.1 - 1.7e-33 115.2 33.3 1.9e-33 115.0 33.3 1.0 1 0 0 1 1 1 1 Cgr1 family Peptidase_C37 PF05416.12 ORY04029.1 - 1.9 6.9 9.9 2.2 6.7 9.9 1.0 1 0 0 1 1 1 0 Southampton virus-type processing peptidase DUF4192 PF13830.6 ORY04029.1 - 6.1 6.8 9.9 7.5 6.5 9.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) RR_TM4-6 PF06459.12 ORY04029.1 - 8.8 6.1 15.1 9.5 5.9 15.1 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Mito_carr PF00153.27 ORY04030.1 - 4.2e-62 206.1 1.3 4.4e-21 74.6 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF1925 PF09094.11 ORY04030.1 - 0.053 13.9 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1925) Tim17 PF02466.19 ORY04031.1 - 3.5e-13 49.9 0.5 5.9e-13 49.2 0.5 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Wzy_C PF04932.15 ORY04034.1 - 0.17 11.5 0.0 0.17 11.5 0.0 2.6 2 1 0 2 2 2 0 O-Antigen ligase Zn_ribbon_SprT PF17283.2 ORY04035.1 - 0.022 14.7 0.1 0.039 13.9 0.1 1.3 1 0 0 1 1 1 0 SprT-like zinc ribbon domain Fasciclin PF02469.22 ORY04036.1 - 0.00023 21.4 0.0 0.00042 20.5 0.0 1.5 1 1 0 1 1 1 1 Fasciclin domain HIRA_B PF09453.10 ORY04036.1 - 0.0014 18.4 0.2 0.0029 17.4 0.2 1.5 1 0 0 1 1 1 1 HIRA B motif DUF3807 PF12720.7 ORY04037.1 - 1.5e-26 93.8 1.5 2.2e-26 93.3 1.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3807) NACHT PF05729.12 ORY04110.1 - 1.6e-08 34.6 0.0 5.7e-08 32.8 0.0 1.9 1 0 0 1 1 1 1 NACHT domain NACHT_N PF17100.5 ORY04110.1 - 0.0013 18.7 0.4 0.0055 16.6 0.4 1.9 1 1 0 1 1 1 1 N-terminal domain of NWD NACHT-NTPase AAA_22 PF13401.6 ORY04110.1 - 0.0025 18.1 1.1 0.027 14.8 0.0 3.0 3 0 0 3 3 3 1 AAA domain Goodbye PF17109.5 ORY04110.1 - 0.0061 17.0 0.8 0.1 13.1 0.0 2.6 2 1 1 3 3 3 1 fungal STAND N-terminal Goodbye domain AAA_19 PF13245.6 ORY04110.1 - 0.016 15.5 0.0 0.049 14.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 ORY04110.1 - 0.025 14.6 0.1 0.43 10.6 0.0 2.3 1 1 0 2 2 2 0 Type III restriction enzyme, res subunit APS_kinase PF01583.20 ORY04110.1 - 0.026 14.4 0.1 7.1 6.5 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_26 PF13500.6 ORY04110.1 - 0.14 12.0 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain Phage_GPO PF05929.11 ORY04110.1 - 0.15 11.7 0.3 0.58 9.7 0.2 1.9 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase AAA PF00004.29 ORY04111.1 - 3.4e-13 50.2 0.0 8.6e-13 48.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 ORY04111.1 - 0.0092 16.4 0.2 0.024 15.0 0.2 1.8 1 1 0 1 1 1 1 AAA ATPase domain Linocin_M18 PF04454.12 ORY04111.1 - 0.05 12.9 0.0 0.14 11.4 0.0 1.7 2 0 0 2 2 2 0 Encapsulating protein for peroxidase Zeta_toxin PF06414.12 ORY04111.1 - 0.079 12.2 0.1 0.18 11.1 0.1 1.5 1 0 0 1 1 1 0 Zeta toxin Torsin PF06309.11 ORY04111.1 - 0.1 12.7 0.0 0.28 11.3 0.0 1.7 1 0 0 1 1 1 0 Torsin AAA_22 PF13401.6 ORY04111.1 - 0.16 12.2 0.2 0.41 10.9 0.2 1.7 1 1 0 1 1 1 0 AAA domain Mannosyl_trans3 PF11051.8 ORY04112.1 - 4e-61 206.8 0.1 4.9e-37 127.8 0.0 2.1 1 1 1 2 2 2 2 Mannosyltransferase putative Peptidase_S8 PF00082.22 ORY04114.1 - 1.6e-32 113.0 17.4 4e-32 111.7 17.4 1.6 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 ORY04114.1 - 8.3e-06 26.4 0.3 6.9e-05 23.4 0.3 2.2 1 1 0 1 1 1 1 Peptidase inhibitor I9 DUF4653 PF15546.6 ORY04114.1 - 0.28 10.8 0.7 0.39 10.3 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4653) Peptidase_S8 PF00082.22 ORY04116.1 - 1.5e-31 109.8 13.3 3.6e-31 108.5 13.0 1.5 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 ORY04116.1 - 7.9e-09 36.1 0.0 5.3e-08 33.4 0.0 2.2 1 1 0 1 1 1 1 Peptidase inhibitor I9 Cu-oxidase_2 PF07731.14 ORY04117.1 - 6.2e-42 142.6 3.2 1.8e-37 128.2 0.1 3.8 3 1 0 3 3 3 3 Multicopper oxidase Cu-oxidase_3 PF07732.15 ORY04117.1 - 1.8e-40 137.7 1.0 1.8e-40 137.7 1.0 3.0 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase PF00394.22 ORY04117.1 - 2.6e-34 118.6 0.9 2.7e-33 115.3 0.3 2.5 2 0 0 2 2 2 1 Multicopper oxidase DUF11 PF01345.18 ORY04117.1 - 0.015 15.6 0.4 1.3 9.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF11 Cep57_MT_bd PF06657.13 ORY04122.1 - 2.1e-24 85.8 0.9 2.1e-24 85.8 0.9 5.9 6 1 0 7 7 7 1 Centrosome microtubule-binding domain of Cep57 Cep57_CLD_2 PF14197.6 ORY04122.1 - 4.2e-16 58.8 5.6 4.2e-16 58.8 5.6 7.0 4 1 2 6 6 6 1 Centrosome localisation domain of PPC89 HALZ PF02183.18 ORY04122.1 - 0.0009 19.4 32.6 0.016 15.4 0.9 7.1 5 1 2 7 7 7 3 Homeobox associated leucine zipper HIP1_clath_bdg PF16515.5 ORY04122.1 - 0.012 16.2 11.4 0.012 16.2 11.4 7.2 4 3 2 7 7 7 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF956 PF06115.11 ORY04123.1 - 0.2 11.4 0.0 0.37 10.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF956) Pkinase PF00069.25 ORY04124.1 - 8.4e-44 149.9 0.0 2.6e-43 148.3 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY04124.1 - 3.1e-30 105.3 0.0 4.7e-30 104.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY04124.1 - 0.0027 17.1 0.0 0.0049 16.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 ORY04124.1 - 0.032 13.6 0.0 0.061 12.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-C2HC_2 PF13913.6 ORY04124.1 - 0.15 12.0 0.7 0.47 10.4 0.7 1.9 1 0 0 1 1 1 0 zinc-finger of a C2HC-type APH PF01636.23 ORY04124.1 - 0.29 11.0 2.7 1.8 8.4 0.3 2.9 2 1 0 2 2 2 0 Phosphotransferase enzyme family Aldose_epim PF01263.20 ORY04125.1 - 3e-40 138.4 0.0 3.5e-40 138.2 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase DUF3126 PF11324.8 ORY04125.1 - 0.029 14.2 0.1 0.21 11.4 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3126) Rif1_N PF12231.8 ORY04126.1 - 5.6e-107 358.0 2.4 9.6e-107 357.2 2.4 1.4 1 0 0 1 1 1 1 Rap1-interacting factor 1 N terminal PWI PF01480.17 ORY04126.1 - 0.09 13.1 0.2 0.73 10.2 0.0 2.7 3 0 0 3 3 3 0 PWI domain Ric8 PF10165.9 ORY04127.1 - 1.1e-129 433.4 2.2 1.3e-129 433.2 2.2 1.0 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn Arg_decarbox_C PF17944.1 ORY04127.1 - 0.032 14.8 0.1 0.14 12.7 0.1 2.2 1 0 0 1 1 1 0 Arginine decarboxylase C-terminal helical extension zf-RING_2 PF13639.6 ORY04129.1 - 5.3e-09 36.3 7.0 7.3e-09 35.8 7.0 1.2 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 ORY04129.1 - 2.5e-06 27.7 7.1 3.9e-06 27.0 7.1 1.4 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 ORY04129.1 - 0.00013 21.9 4.9 0.00018 21.5 4.9 1.3 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 ORY04129.1 - 0.00031 20.7 1.7 0.00084 19.3 1.7 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 ORY04129.1 - 0.00052 19.8 4.2 0.0014 18.5 4.2 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 ORY04129.1 - 0.0026 17.5 1.9 0.0085 15.8 1.9 1.9 1 1 0 1 1 1 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 ORY04129.1 - 0.0033 17.2 5.9 0.0073 16.1 5.9 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 ORY04129.1 - 0.025 14.4 6.5 0.19 11.6 6.5 2.1 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 ORY04129.1 - 0.04 13.8 9.8 1.2 9.1 9.8 2.4 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 ORY04129.1 - 0.15 12.2 6.0 0.51 10.5 6.0 1.9 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-UDP PF14569.6 ORY04129.1 - 0.9 9.7 4.4 2.4 8.4 4.4 1.7 1 1 0 1 1 1 0 Zinc-binding RING-finger zf-RING_4 PF14570.6 ORY04129.1 - 2.6 7.9 8.8 58 3.6 8.8 2.2 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain His_Phos_2 PF00328.22 ORY04131.1 - 8.5e-09 35.2 0.1 1.2e-06 28.2 0.0 2.8 2 1 1 3 3 3 2 Histidine phosphatase superfamily (branch 2) DUF2567 PF10821.8 ORY04131.1 - 0.11 12.6 1.0 5.6 7.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2567) HET PF06985.11 ORY04132.1 - 4.7e-05 23.8 0.0 9.3e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Cyclin_C_2 PF16899.5 ORY04132.1 - 0.12 12.7 0.0 33 4.9 0.0 2.6 2 0 0 2 2 2 0 Cyclin C-terminal domain MFS_MOT1 PF16983.5 ORY04133.1 - 2.2e-56 189.0 27.9 2.4e-30 105.2 8.5 2.4 2 0 0 2 2 2 2 Molybdate transporter of MFS superfamily zf-RING_2 PF13639.6 ORY04135.1 - 1.5e-09 38.0 2.8 2.2e-09 37.5 2.8 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 ORY04135.1 - 1e-06 28.9 4.4 1.3e-05 25.4 4.5 2.2 1 1 1 2 2 2 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 ORY04135.1 - 0.00033 20.7 0.5 0.0005 20.1 0.5 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 ORY04135.1 - 0.00038 20.2 5.1 0.0027 17.5 5.2 2.0 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 ORY04135.1 - 0.0016 18.2 1.7 0.0026 17.5 1.7 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 ORY04135.1 - 0.0017 18.4 5.3 0.0029 17.6 5.3 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 ORY04135.1 - 0.0055 16.6 1.6 0.01 15.7 1.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PUL PF08324.11 ORY04135.1 - 0.098 11.9 0.2 0.59 9.3 0.1 1.9 1 1 1 2 2 2 0 PUL domain zf-C3HC4_3 PF13920.6 ORY04135.1 - 0.16 11.8 1.7 0.79 9.6 1.6 1.9 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Fungal_trans PF04082.18 ORY04136.1 - 7.2e-05 21.9 0.1 0.00013 21.1 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain F-box-like PF12937.7 ORY04137.1 - 0.11 12.4 2.8 0.39 10.6 0.5 2.5 2 0 0 2 2 2 0 F-box-like Diphthamide_syn PF01866.17 ORY04138.1 - 3.6e-86 289.3 0.0 5.8e-86 288.7 0.0 1.3 1 1 0 1 1 1 1 Putative diphthamide synthesis protein SRP-alpha_N PF04086.13 ORY04138.1 - 0.052 13.5 0.8 0.097 12.6 0.8 1.4 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal CFC PF09443.10 ORY04139.1 - 0.12 12.2 0.3 0.12 12.2 0.3 1.9 2 0 0 2 2 2 0 Cripto_Frl-1_Cryptic (CFC) HET PF06985.11 ORY04140.1 - 2.3e-05 24.8 0.1 7.2e-05 23.2 0.0 1.9 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) PLA2_B PF01735.18 ORY04141.1 - 9.2e-192 637.8 3.9 1.1e-191 637.6 3.9 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain His_Phos_1 PF00300.22 ORY04142.1 - 2.3e-17 63.3 0.0 3.2e-17 62.9 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) MFS_1 PF07690.16 ORY04143.1 - 1.2e-23 83.7 44.4 1.2e-23 83.7 44.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Zn_clus PF00172.18 ORY04144.1 - 6e-05 23.1 7.7 0.00011 22.3 7.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ORY04144.1 - 0.00015 20.9 0.1 0.00032 19.8 0.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF3509 PF12021.8 ORY04144.1 - 0.13 12.0 0.3 0.67 9.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3509) Abhydrolase_6 PF12697.7 ORY04145.1 - 2e-13 51.4 0.1 3.4e-13 50.7 0.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ORY04145.1 - 2.5e-13 50.2 0.1 3.7e-13 49.7 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ORY04145.1 - 0.00019 20.8 0.0 0.00026 20.3 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 ORY04145.1 - 0.003 17.7 0.0 0.0035 17.5 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_3 PF07859.13 ORY04145.1 - 0.051 13.4 0.0 0.073 12.9 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Ndr PF03096.14 ORY04145.1 - 0.12 11.0 0.0 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 Ndr family Uso1_p115_head PF04869.14 ORY04146.1 - 4.2e-112 374.3 0.0 1.1e-111 372.9 0.0 1.8 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.13 ORY04146.1 - 9.7e-18 64.8 35.9 9.7e-18 64.8 35.9 3.6 1 1 1 2 2 2 1 Uso1 / p115 like vesicle tethering protein, C terminal region MFS_1 PF07690.16 ORY04147.1 - 7e-47 160.1 49.4 7e-47 160.1 49.4 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily XRN_M PF17846.1 ORY04148.1 - 3.6e-137 458.0 5.2 1.2e-136 456.2 0.1 2.5 2 1 0 2 2 2 1 Xrn1 helical domain XRN_N PF03159.18 ORY04148.1 - 1.5e-100 335.6 0.0 2.3e-100 335.0 0.0 1.3 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus Med21 PF11221.8 ORY04189.1 - 0.014 15.6 1.3 0.014 15.6 1.3 5.1 5 0 0 5 5 5 0 Subunit 21 of Mediator complex DUF4407 PF14362.6 ORY04189.1 - 1.4 8.2 9.1 0.29 10.4 0.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Spt20 PF12090.8 ORY04189.1 - 6.7 6.2 20.8 23 4.5 20.8 1.9 1 0 0 1 1 1 0 Spt20 family zf-C3H1 PF10650.9 ORY04190.1 - 4.2e-11 42.3 2.3 6.7e-11 41.7 2.3 1.3 1 0 0 1 1 1 1 Putative zinc-finger domain adh_short PF00106.25 ORY04191.1 - 1.1e-26 93.5 0.0 1.9e-26 92.7 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY04191.1 - 4.8e-22 78.7 0.0 1.3e-21 77.2 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY04191.1 - 0.031 14.2 0.0 3.9 7.4 0.0 2.1 2 0 0 2 2 2 0 KR domain TAL_FSA PF00923.19 ORY04192.1 - 4.6e-94 315.0 1.2 5.2e-94 314.8 1.2 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase C5-epim_C PF06662.13 ORY04192.1 - 0.027 14.0 0.0 0.047 13.2 0.0 1.3 1 0 0 1 1 1 0 D-glucuronyl C5-epimerase C-terminus Sod_Cu PF00080.20 ORY04193.1 - 1e-46 158.6 6.7 1.2e-46 158.4 6.7 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) SNase PF00565.17 ORY04194.1 - 4.8e-75 249.0 4.6 9.6e-26 90.4 0.0 5.5 5 0 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.24 ORY04194.1 - 1.2e-23 83.4 0.0 2.5e-23 82.4 0.0 1.5 1 0 0 1 1 1 1 Tudor domain Ferric_reduct PF01794.19 ORY04196.1 - 2.5e-19 69.6 6.2 2.5e-19 69.6 6.2 3.1 3 1 0 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 ORY04196.1 - 1.8e-13 50.9 0.0 2.8e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 ORY04196.1 - 4.6e-12 46.0 0.0 1.2e-11 44.7 0.0 1.7 1 1 0 1 1 1 1 FAD-binding domain DUF745 PF05335.13 ORY04197.1 - 0.00026 20.8 4.0 0.0003 20.6 4.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF745) HemX PF04375.14 ORY04197.1 - 0.24 10.7 3.9 0.26 10.6 3.9 1.0 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase Atg14 PF10186.9 ORY04197.1 - 0.27 10.3 2.2 0.31 10.1 2.2 1.0 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF531 PF04407.12 ORY04198.1 - 0.15 12.2 0.0 0.16 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF531) DUF3435 PF11917.8 ORY04199.1 - 5.7e-07 28.8 0.0 5.8e-07 28.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) Pyr_redox_2 PF07992.14 ORY04258.1 - 7.6e-40 137.0 0.0 4.4e-35 121.3 0.0 2.1 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORY04258.1 - 7.9e-11 42.4 0.0 3.3e-09 37.2 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ORY04258.1 - 0.00014 21.6 0.0 7.1 6.1 0.0 3.2 2 1 0 3 3 3 3 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ORY04258.1 - 0.032 14.5 0.0 2.8 8.2 0.0 2.9 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.20 ORY04258.1 - 0.17 12.0 0.0 0.38 10.8 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase TPR_2 PF07719.17 ORY04259.1 - 0.0022 18.0 0.1 0.0063 16.5 0.1 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 ORY04259.1 - 0.003 17.3 0.1 0.0063 16.3 0.1 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 ORY04259.1 - 0.0042 17.2 0.0 0.012 15.8 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.6 ORY04259.1 - 0.0079 15.9 0.3 0.014 15.0 0.3 1.4 1 0 0 1 1 1 1 TPR repeat TPR_12 PF13424.6 ORY04259.1 - 0.013 15.8 0.4 0.043 14.1 0.3 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat FAT PF02259.23 ORY04259.1 - 0.027 13.7 0.2 0.027 13.7 0.2 1.5 2 0 0 2 2 2 0 FAT domain TRAPPC9-Trs120 PF08626.11 ORY04259.1 - 0.029 11.8 0.0 0.029 11.8 0.0 1.7 2 1 0 2 2 2 0 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit TPR_14 PF13428.6 ORY04259.1 - 0.031 15.1 0.4 0.35 11.8 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat RasGAP PF00616.19 ORY04260.1 - 4.8e-59 199.6 0.5 1.7e-58 197.8 0.0 2.0 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 ORY04260.1 - 7.1e-30 103.9 3.2 7.1e-30 103.9 3.2 2.7 3 0 0 3 3 3 1 RasGAP C-terminus DUF1647 PF07801.11 ORY04260.1 - 0.098 12.4 1.7 0.18 11.5 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1647) RANK_CRD_2 PF18278.1 ORY04261.1 - 0.11 12.7 0.1 0.26 11.5 0.1 1.5 1 0 0 1 1 1 0 Receptor activator of the NF-KB cysteine-rich repeat domain 2 Mis14 PF08641.12 ORY04262.1 - 1.1e-06 29.0 0.0 2.5e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Kinetochore protein Mis14 like Ribosomal_S15 PF00312.22 ORY04262.1 - 0.3 11.3 1.9 3.8 7.8 0.1 2.3 2 0 0 2 2 2 0 Ribosomal protein S15 MOZ_SAS PF01853.18 ORY04263.1 - 1.2e-65 220.5 0.0 1.6e-65 220.1 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 ORY04263.1 - 7.9e-17 60.6 0.2 1.4e-16 59.8 0.2 1.4 1 0 0 1 1 1 1 MYST family zinc finger domain Acetyltransf_7 PF13508.7 ORY04263.1 - 0.0025 18.2 0.0 0.0058 17.0 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORY04263.1 - 0.025 14.8 0.0 0.11 12.8 0.0 2.0 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ORY04263.1 - 0.084 12.8 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain SAGA-Tad1 PF12767.7 ORY04265.1 - 0.15 11.8 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit HEM4 PF02602.15 ORY04266.1 - 1e-38 133.0 0.0 1.7e-37 129.0 0.0 2.2 2 0 0 2 2 2 1 Uroporphyrinogen-III synthase HemD Pyrid_ox_like PF16242.5 ORY04268.1 - 2.3e-27 95.4 0.0 3.4e-27 94.9 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase like Putative_PNPOx PF01243.20 ORY04268.1 - 9.9e-08 32.1 0.0 2.1e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase FMN_bind_2 PF04299.12 ORY04268.1 - 0.13 12.0 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 Putative FMN-binding domain RNA_pol_Rpb2_6 PF00562.28 ORY04269.1 - 4.2e-108 361.9 0.0 3.4e-105 352.3 0.0 2.1 2 0 0 2 2 2 2 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 ORY04269.1 - 4.1e-36 124.4 0.0 6.5e-36 123.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 ORY04269.1 - 6.5e-27 93.5 0.0 1.4e-26 92.4 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpa2_4 PF06883.12 ORY04269.1 - 1.9e-25 88.6 0.0 4.3e-25 87.5 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_2 PF04561.14 ORY04269.1 - 6.6e-23 81.3 0.0 1.1e-22 80.6 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 ORY04269.1 - 6.1e-15 55.4 0.0 5.9e-14 52.2 0.0 2.4 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 7 Carla_C4 PF01623.17 ORY04269.1 - 0.16 11.9 0.7 0.42 10.6 0.7 1.6 1 0 0 1 1 1 0 Carlavirus putative nucleic acid binding protein Arf PF00025.21 ORY04270.1 - 2.9e-44 150.6 0.0 3.5e-44 150.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 ORY04270.1 - 3.8e-18 65.6 0.0 4.4e-18 65.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY04270.1 - 1.9e-15 57.1 0.0 3e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 ORY04270.1 - 3.9e-07 29.7 0.0 4.7e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 ORY04270.1 - 2e-06 27.8 0.0 2.8e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 ORY04270.1 - 6e-06 25.8 0.0 7e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 ORY04270.1 - 0.0021 17.3 0.2 0.0096 15.1 0.0 2.0 1 1 1 2 2 2 1 G-protein alpha subunit FeoB_N PF02421.18 ORY04270.1 - 0.0067 16.0 0.2 0.015 14.8 0.2 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 ORY04270.1 - 0.1 12.6 0.1 0.3 11.1 0.1 1.6 1 1 1 2 2 2 0 Dynamin family MMR_HSR1_Xtn PF16897.5 ORY04270.1 - 0.15 12.1 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain PP1_inhibitor PF05361.12 ORY04270.1 - 0.18 11.8 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 PKC-activated protein phosphatase-1 inhibitor RCR PF12273.8 ORY04272.1 - 6.5e-22 78.4 11.9 8e-22 78.1 11.9 1.1 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red SARAF PF06682.12 ORY04272.1 - 0.00011 22.0 0.5 0.00013 21.8 0.5 1.1 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis Shisa PF13908.6 ORY04272.1 - 0.00027 21.2 0.0 0.00039 20.7 0.0 1.1 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator CYYR1 PF10873.8 ORY04272.1 - 0.0084 16.6 1.9 0.0084 16.6 1.9 1.6 1 1 1 2 2 2 1 Cysteine and tyrosine-rich protein 1 DUF2207 PF09972.9 ORY04272.1 - 0.12 11.1 0.1 0.13 11.0 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) K_oxygenase PF13434.6 ORY04273.1 - 2.1e-17 63.3 0.0 3e-15 56.2 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 ORY04273.1 - 1.9e-14 53.6 0.1 1.1e-11 44.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ORY04273.1 - 1.1e-12 47.8 0.0 1.9e-11 43.8 0.0 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 ORY04273.1 - 8.7e-10 37.6 0.0 1.2e-08 33.8 0.0 2.2 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 ORY04273.1 - 7.4e-07 29.3 0.1 5.6e-05 23.3 0.0 2.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 ORY04273.1 - 2.5e-06 27.6 1.5 0.0089 16.0 0.0 3.7 3 1 0 3 3 3 2 FAD-NAD(P)-binding Thi4 PF01946.17 ORY04273.1 - 5.8e-06 25.7 1.1 0.00078 18.7 0.2 2.3 2 0 0 2 2 2 2 Thi4 family HI0933_like PF03486.14 ORY04273.1 - 0.00051 18.9 2.1 0.47 9.1 0.1 4.0 5 0 0 5 5 5 2 HI0933-like protein DAO PF01266.24 ORY04273.1 - 0.00082 19.0 7.4 0.052 13.1 0.3 3.5 3 1 1 4 4 4 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 ORY04273.1 - 0.018 14.1 0.5 0.11 11.5 0.1 2.5 3 1 0 3 3 3 0 Lycopene cyclase protein FAD_binding_2 PF00890.24 ORY04273.1 - 0.023 13.8 2.6 0.15 11.1 0.1 2.6 3 0 0 3 3 3 0 FAD binding domain FAD_oxidored PF12831.7 ORY04273.1 - 0.024 14.0 0.2 0.25 10.6 0.0 2.3 3 0 0 3 3 3 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 ORY04273.1 - 0.024 15.2 1.2 13 6.4 0.0 3.1 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 ORY04273.1 - 0.034 13.2 1.9 2.5 7.1 0.1 3.1 3 0 0 3 3 3 0 Glucose inhibited division protein A adh_short_C2 PF13561.6 ORY04274.1 - 4.8e-41 140.8 0.1 6e-40 137.3 0.1 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY04274.1 - 1.3e-30 106.4 0.1 1.5e-29 102.8 0.1 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORY04274.1 - 1e-09 38.6 0.1 1.5e-09 38.0 0.1 1.2 1 0 0 1 1 1 1 KR domain HATPase_c PF02518.26 ORY04274.1 - 0.049 14.1 0.0 0.12 12.9 0.0 1.6 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase FAD_binding_3 PF01494.19 ORY04275.1 - 6.2e-05 22.4 0.0 0.00013 21.3 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain FAA_hydrolase PF01557.18 ORY04276.1 - 5e-58 196.3 0.0 5.9e-58 196.1 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family eIF-1a PF01176.19 ORY04276.1 - 0.13 12.0 0.1 0.68 9.8 0.0 2.1 2 0 0 2 2 2 0 Translation initiation factor 1A / IF-1 Tnp_P_element_C PF12596.8 ORY04276.1 - 0.17 12.4 0.1 0.36 11.4 0.1 1.5 1 0 0 1 1 1 0 87kDa Transposase Cupin_2 PF07883.11 ORY04277.1 - 1.8e-27 94.8 0.9 2.1e-15 56.2 0.1 2.3 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.19 ORY04277.1 - 1.1e-05 25.3 0.1 0.00072 19.5 0.0 2.3 2 0 0 2 2 2 1 AraC-like ligand binding domain Cupin_3 PF05899.12 ORY04277.1 - 7.1e-05 22.4 0.0 0.37 10.5 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) CENP-C_C PF11699.8 ORY04277.1 - 0.0014 18.8 0.0 0.0033 17.6 0.0 1.5 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_1 PF00190.22 ORY04277.1 - 0.0025 17.4 0.0 0.59 9.7 0.0 2.4 2 0 0 2 2 2 2 Cupin ARD PF03079.14 ORY04277.1 - 0.0091 16.2 0.1 1.2 9.3 0.0 2.4 2 0 0 2 2 2 1 ARD/ARD' family EutQ PF06249.12 ORY04277.1 - 0.21 11.3 0.0 10 5.8 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation protein EutQ Lipocalin_5 PF13924.6 ORY04278.1 - 3.7e-16 59.2 0.0 4.9e-16 58.8 0.0 1.2 1 0 0 1 1 1 1 Lipocalin-like domain NFACT-C PF11923.8 ORY04279.1 - 4.8e-38 129.3 0.0 4.8e-38 129.3 0.0 3.4 4 0 0 4 4 4 1 NFACT protein C-terminal domain FbpA PF05833.11 ORY04279.1 - 5.1e-36 124.4 3.6 5.1e-36 124.4 3.6 1.8 2 1 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) NFACT-R_1 PF05670.13 ORY04279.1 - 3.7e-28 98.4 0.0 8.1e-28 97.2 0.0 1.6 1 0 0 1 1 1 1 NFACT protein RNA binding domain Serine_rich PF08824.10 ORY04279.1 - 0.31 11.0 4.2 0.087 12.8 0.8 1.8 2 0 0 2 2 2 0 Serine rich protein interaction domain Clat_adaptor_s PF01217.20 ORY04280.1 - 6.9e-13 48.7 0.9 1.3e-12 47.8 0.9 1.4 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Sterol_MT_C PF08498.10 ORY04286.1 - 7.6e-18 64.6 0.2 1.5e-17 63.6 0.2 1.5 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_25 PF13649.6 ORY04286.1 - 5e-05 23.9 2.0 0.012 16.3 0.1 2.5 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 ORY04286.1 - 0.00036 21.1 3.3 0.0017 19.0 0.1 2.8 1 1 1 2 2 2 1 Methyltransferase domain CMAS PF02353.20 ORY04286.1 - 0.00048 19.5 0.0 0.00084 18.7 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 ORY04286.1 - 0.0035 17.2 0.0 0.0067 16.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY04286.1 - 0.017 14.9 0.7 0.81 9.5 0.2 2.6 1 1 1 2 2 2 0 Methyltransferase domain PCMT PF01135.19 ORY04286.1 - 0.038 13.8 0.0 0.06 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.18 ORY04286.1 - 0.063 12.6 0.2 1.4 8.1 0.0 2.4 1 1 1 2 2 2 0 ubiE/COQ5 methyltransferase family SNF2_N PF00176.23 ORY04287.1 - 7.5e-58 195.9 0.0 1.2e-57 195.2 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.10 ORY04287.1 - 2.1e-57 194.2 0.8 3.9e-57 193.3 0.8 1.4 1 0 0 1 1 1 1 Rad54 N terminal Helicase_C PF00271.31 ORY04287.1 - 5.6e-15 55.7 0.0 2.5e-14 53.6 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY04287.1 - 1.4e-06 28.4 0.0 2.6e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 ORY04287.1 - 0.13 11.9 0.0 0.37 10.4 0.0 1.8 1 0 0 1 1 1 0 SWI2/SNF2 ATPase ADH_zinc_N PF00107.26 ORY04288.1 - 7.6e-26 90.6 0.0 1.3e-25 89.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ORY04288.1 - 1.5e-20 73.1 5.3 2.7e-20 72.3 5.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 ORY04288.1 - 0.0017 17.7 0.1 0.0025 17.1 0.1 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 ORY04288.1 - 0.002 17.5 0.1 0.0035 16.7 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_25 PF13649.6 ORY04288.1 - 0.0043 17.7 0.1 0.022 15.4 0.1 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY04288.1 - 0.017 14.9 0.1 0.031 14.1 0.1 1.4 1 0 0 1 1 1 0 Methyltransferase domain ADH_N_2 PF16884.5 ORY04288.1 - 0.018 14.9 0.0 0.04 13.8 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase Methyltransf_11 PF08241.12 ORY04288.1 - 0.035 14.8 0.1 0.19 12.4 0.1 2.2 2 0 0 2 2 2 0 Methyltransferase domain 3HCDH_N PF02737.18 ORY04288.1 - 0.085 12.7 0.2 0.12 12.3 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PglD_N PF17836.1 ORY04288.1 - 0.11 13.2 0.6 0.3 11.8 0.6 1.8 1 0 0 1 1 1 0 PglD N-terminal domain MFS_1 PF07690.16 ORY04289.1 - 1.9e-33 115.9 26.8 3e-33 115.2 26.8 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Cellulase PF00150.18 ORY04290.1 - 1.7e-20 73.6 4.8 2.4e-20 73.1 4.8 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) ADH_zinc_N_2 PF13602.6 ORY04291.1 - 1.8e-17 64.7 0.0 4e-17 63.5 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 ORY04291.1 - 1.6e-16 60.5 0.0 3.5e-16 59.3 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ORY04291.1 - 4.2e-11 42.7 0.0 1.1e-07 31.7 0.0 2.8 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 ORY04291.1 - 0.084 12.8 0.0 0.24 11.3 0.0 1.8 1 1 0 1 1 1 0 N-terminal domain of oxidoreductase Glyoxalase PF00903.25 ORY04292.1 - 2.4e-07 31.0 0.0 3.9e-07 30.3 0.0 1.4 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily CutC PF03932.14 ORY04293.1 - 1.1e-37 129.5 0.2 1.6e-25 89.8 0.0 2.0 1 1 1 2 2 2 2 CutC family TP_methylase PF00590.20 ORY04297.1 - 2.2e-25 89.8 0.5 4.6e-25 88.8 0.5 1.5 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases PLRV_ORF5 PF01690.17 ORY04297.1 - 0.22 10.2 0.0 0.23 10.1 0.0 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein TFIID-18kDa PF02269.16 ORY04298.1 - 1.4e-23 82.7 0.2 5.4e-23 80.8 0.1 1.9 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit ALMS_repeat PF18727.1 ORY04298.1 - 0.2 11.6 0.2 0.38 10.7 0.2 1.4 1 0 0 1 1 1 0 Alstrom syndrome repeat Ribosomal_L19e PF01280.20 ORY04299.1 - 9.5e-53 178.1 12.3 2.1e-51 173.8 12.3 2.6 1 1 0 1 1 1 1 Ribosomal protein L19e FUSC_2 PF13515.6 ORY04299.1 - 1.8e-31 108.9 5.5 1.8e-31 108.9 5.5 3.0 2 1 1 3 3 3 1 Fusaric acid resistance protein-like ArAE_2 PF10334.9 ORY04299.1 - 0.00043 20.2 0.2 0.0026 17.6 0.0 2.1 2 0 0 2 2 2 1 Aromatic acid exporter family member 2 ALMT PF11744.8 ORY04299.1 - 0.00068 18.6 2.0 0.00068 18.6 2.0 4.1 5 0 0 5 5 5 2 Aluminium activated malate transporter Phage_holin_Dp1 PF16938.5 ORY04299.1 - 0.042 14.1 3.8 0.43 10.8 0.1 3.3 3 0 0 3 3 3 0 Putative phage holin Dp-1 FUSC PF04632.12 ORY04299.1 - 0.11 11.0 12.4 1 7.8 0.0 3.7 4 0 0 4 4 4 0 Fusaric acid resistance protein family ABC2_membrane_3 PF12698.7 ORY04299.1 - 0.27 10.3 11.3 0.6 9.1 11.3 1.5 1 0 0 1 1 1 0 ABC-2 family transporter protein Peptidase_U4 PF03419.13 ORY04299.1 - 1 8.6 17.8 0.016 14.5 1.8 2.9 2 1 1 3 3 3 0 Sporulation factor SpoIIGA Phage_holin_3_7 PF05449.11 ORY04299.1 - 1.2 9.2 6.2 3.3 7.8 1.8 3.2 2 1 1 3 3 3 0 Putative 3TM holin, Phage_holin_3 MPLKIP PF15502.6 ORY04300.1 - 7.5e-05 22.9 0.3 0.00022 21.4 0.0 1.9 2 0 0 2 2 2 1 M-phase-specific PLK1-interacting protein SNRNP27 PF08648.12 ORY04300.1 - 0.026 14.6 0.1 0.062 13.4 0.1 1.6 2 0 0 2 2 2 0 U4/U6.U5 small nuclear ribonucleoproteins KxDL PF10241.9 ORY04301.1 - 6.2e-32 109.7 0.2 7.9e-32 109.4 0.2 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein AAA PF00004.29 ORY04302.1 - 1.6e-44 151.5 0.0 5.1e-28 98.1 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 ORY04302.1 - 3.4e-11 42.8 0.1 1.1e-10 41.1 0.1 1.9 2 0 0 2 2 2 1 AAA+ lid domain AAA_22 PF13401.6 ORY04302.1 - 4.7e-06 26.9 0.1 0.044 14.1 0.0 3.8 2 1 1 3 3 3 1 AAA domain AAA_2 PF07724.14 ORY04302.1 - 0.00055 20.1 0.2 0.21 11.7 0.1 2.7 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 ORY04302.1 - 0.0006 20.2 0.1 0.006 17.0 0.0 2.6 3 1 1 4 4 4 1 AAA ATPase domain AAA_14 PF13173.6 ORY04302.1 - 0.0017 18.4 0.0 0.031 14.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 ORY04302.1 - 0.0022 17.3 0.0 0.0038 16.5 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_24 PF13479.6 ORY04302.1 - 0.0023 17.7 0.1 0.0086 15.8 0.0 2.0 2 1 0 2 2 2 1 AAA domain NACHT PF05729.12 ORY04302.1 - 0.0039 17.1 0.2 0.033 14.1 0.0 2.5 3 0 0 3 3 3 1 NACHT domain RuvB_N PF05496.12 ORY04302.1 - 0.0055 16.5 0.1 0.1 12.3 0.0 2.9 4 0 0 4 4 4 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 ORY04302.1 - 0.021 15.0 0.0 0.043 14.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 ORY04302.1 - 0.025 14.5 0.0 28 4.5 0.0 3.1 2 1 0 3 3 3 0 ATPase domain predominantly from Archaea NB-ARC PF00931.22 ORY04302.1 - 0.03 13.5 0.0 0.079 12.1 0.0 1.6 1 1 0 1 1 1 0 NB-ARC domain AAA_25 PF13481.6 ORY04302.1 - 0.053 13.1 0.6 0.78 9.3 0.1 2.7 3 0 0 3 3 3 0 AAA domain AAA_17 PF13207.6 ORY04302.1 - 0.066 13.6 0.0 0.18 12.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 ORY04302.1 - 0.1 13.1 0.0 2.2 8.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 ORY04302.1 - 0.1 13.0 0.0 0.26 11.7 0.0 1.7 1 0 0 1 1 1 0 RNA helicase MGC-24 PF05283.11 ORY04351.1 - 0.0015 19.0 5.5 0.0034 17.8 5.5 1.6 1 0 0 1 1 1 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin Gram_pos_anchor PF00746.21 ORY04351.1 - 0.092 12.7 1.0 4.1 7.4 1.2 2.5 2 0 0 2 2 2 0 LPXTG cell wall anchor motif OppC_N PF12911.7 ORY04351.1 - 0.64 10.0 4.0 1.8 8.6 0.6 2.5 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C Alpha_GJ PF03229.13 ORY04351.1 - 7.7 7.1 16.3 0.3 11.6 10.1 1.8 2 0 0 2 2 2 0 Alphavirus glycoprotein J Metallophos PF00149.28 ORY04352.1 - 3.8e-08 34.1 0.3 8.4e-08 33.0 0.3 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase CrgA PF06781.12 ORY04352.1 - 1.1 9.3 3.1 1.8 8.7 1.3 2.0 2 0 0 2 2 2 0 Cell division protein CrgA MTHFR PF02219.17 ORY04353.1 - 3.4e-99 331.8 0.0 4.8e-99 331.3 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Amidohydro_2 PF04909.14 ORY04354.1 - 5.3e-33 115.0 0.4 8.6e-33 114.4 0.4 1.3 1 1 0 1 1 1 1 Amidohydrolase FAD-oxidase_C PF02913.19 ORY04355.1 - 1.5e-59 201.7 0.0 2e-59 201.3 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 ORY04355.1 - 9.3e-36 122.6 0.2 1.8e-35 121.7 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain Proteasome PF00227.26 ORY04356.1 - 1.6e-56 190.8 0.1 2.1e-56 190.5 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 ORY04356.1 - 6.2e-13 48.2 0.3 2.1e-12 46.5 0.1 2.0 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature JHBP PF06585.11 ORY04356.1 - 0.17 11.0 0.0 0.25 10.5 0.0 1.2 1 0 0 1 1 1 0 Haemolymph juvenile hormone binding protein (JHBP) MAT1-1-2 PF17043.5 ORY04356.1 - 0.2 11.5 0.0 0.34 10.7 0.0 1.3 1 0 0 1 1 1 0 Mating type protein 1-1-2 of unknown function zf-CHY PF05495.12 ORY04357.1 - 6.6e-13 49.0 16.3 1.4e-12 47.9 16.3 1.5 1 0 0 1 1 1 1 CHY zinc finger zf_UBZ PF18439.1 ORY04357.1 - 0.0017 17.9 5.5 1.7 8.3 0.2 3.3 3 0 0 3 3 3 2 Ubiquitin-Binding Zinc Finger ArfGap PF01412.18 ORY04357.1 - 0.0092 16.1 0.8 0.0092 16.1 0.8 1.6 1 1 0 1 1 1 1 Putative GTPase activating protein for Arf zinc_ribbon_9 PF14369.6 ORY04357.1 - 0.02 15.1 3.6 0.02 15.1 3.6 2.6 1 1 2 3 3 3 0 zinc-ribbon HypA PF01155.19 ORY04357.1 - 0.41 10.7 9.8 2.5 8.2 9.7 2.1 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C2H2 PF00096.26 ORY04357.1 - 0.89 10.1 8.4 4.3 8.0 0.7 3.5 3 0 0 3 3 3 0 Zinc finger, C2H2 type Evr1_Alr PF04777.13 ORY04357.1 - 1.2 9.6 10.1 90 3.6 10.1 2.7 1 1 0 1 1 1 0 Erv1 / Alr family Zn-ribbon_8 PF09723.10 ORY04357.1 - 3.9 7.7 15.9 0.14 12.3 5.6 2.6 1 1 2 3 3 3 0 Zinc ribbon domain GFA PF04828.14 ORY04359.1 - 7.3e-10 39.1 1.4 7.3e-10 39.1 1.4 1.8 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme zf-LSD1 PF06943.12 ORY04359.1 - 0.47 10.4 5.4 7.3 6.5 0.3 2.6 2 0 0 2 2 2 0 LSD1 zinc finger DUF3176 PF11374.8 ORY04361.1 - 3.6e-28 97.9 2.7 3.6e-28 97.9 2.7 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) AMP-binding PF00501.28 ORY04362.1 - 3.8e-93 312.4 0.0 4.9e-93 312.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORY04362.1 - 7e-12 46.2 0.3 1.8e-11 44.8 0.3 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain adh_short PF00106.25 ORY04363.1 - 1.9e-46 158.0 0.0 2.4e-46 157.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY04363.1 - 1.9e-32 112.7 0.0 2.4e-32 112.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY04363.1 - 1.3e-12 48.0 0.0 1.9e-12 47.5 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 ORY04363.1 - 0.0077 15.4 0.0 0.014 14.5 0.0 1.4 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.8 ORY04363.1 - 0.039 13.7 0.6 0.079 12.7 0.6 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase HAMP PF00672.25 ORY04363.1 - 0.059 13.7 0.0 0.15 12.5 0.0 1.6 1 0 0 1 1 1 0 HAMP domain Sacchrp_dh_NADP PF03435.18 ORY04363.1 - 0.17 12.2 0.0 0.3 11.3 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain UPF0047 PF01894.17 ORY04364.1 - 1.9e-37 127.9 0.0 2.4e-37 127.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 zf-CHCC PF10276.9 ORY04365.1 - 6.5e-17 61.3 1.3 1e-16 60.6 1.3 1.3 1 0 0 1 1 1 1 Zinc-finger domain FLILHELTA PF10306.9 ORY04367.1 - 3.4e-32 110.7 0.3 5.3e-32 110.1 0.3 1.3 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA DUF1279 PF06916.13 ORY04367.1 - 0.0036 17.8 0.3 0.0045 17.5 0.3 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1279) GMC_oxred_N PF00732.19 ORY04369.1 - 2.7e-58 197.7 0.0 3.4e-58 197.3 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 ORY04369.1 - 9.3e-33 113.8 0.1 1.5e-32 113.1 0.1 1.3 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 ORY04369.1 - 7.2e-05 22.9 0.0 0.00024 21.3 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ORY04369.1 - 0.00092 18.9 3.2 0.013 15.1 3.2 2.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 ORY04369.1 - 0.0016 17.5 0.0 0.0028 16.8 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 ORY04369.1 - 0.0058 15.9 0.0 0.038 13.2 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ORY04369.1 - 0.075 13.0 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding Dynamin_N PF00350.23 ORY04371.1 - 0.074 13.1 0.3 0.39 10.8 0.1 2.1 2 0 0 2 2 2 0 Dynamin family AAA_18 PF13238.6 ORY04371.1 - 0.15 12.6 0.0 22 5.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 ORY04371.1 - 0.16 12.5 0.1 1.5 9.3 0.0 2.6 2 0 0 2 2 2 0 ABC transporter DUF2231 PF09990.9 ORY04372.1 - 0.1 13.1 0.3 0.28 11.6 0.3 1.8 1 0 0 1 1 1 0 Predicted membrane protein (DUF2231) ADIP PF11559.8 ORY04373.1 - 0.00081 19.5 6.6 0.00081 19.5 6.6 5.8 2 2 4 6 6 6 2 Afadin- and alpha -actinin-Binding FOXP-CC PF16159.5 ORY04373.1 - 0.36 11.5 11.4 1.7 9.4 2.4 3.2 2 0 0 2 2 2 0 FOXP coiled-coil domain TSC22 PF01166.18 ORY04373.1 - 6.4 7.2 9.9 2.6 8.4 0.2 4.5 5 0 0 5 5 5 0 TSC-22/dip/bun family HET PF06985.11 ORY04374.1 - 0.49 10.7 5.3 3.7 7.9 1.0 3.0 2 2 1 3 3 3 0 Heterokaryon incompatibility protein (HET) CoaE PF01121.20 ORY04377.1 - 1.3e-41 142.2 0.0 2e-41 141.6 0.0 1.2 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_33 PF13671.6 ORY04377.1 - 0.0037 17.4 0.0 0.03 14.5 0.0 2.3 1 1 0 1 1 1 1 AAA domain CcmH PF03918.14 ORY04377.1 - 0.031 13.6 0.3 0.054 12.8 0.3 1.4 1 0 0 1 1 1 0 Cytochrome C biogenesis protein AAA_18 PF13238.6 ORY04377.1 - 0.033 14.7 0.4 0.53 10.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF1691 PF07950.11 ORY04377.1 - 1.5 9.6 4.3 1.5 9.5 0.9 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1691) NUDIX_2 PF13869.6 ORY04378.1 - 6.6e-80 267.1 0.0 7.9e-80 266.9 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase RmlD_sub_bind PF04321.17 ORY04379.1 - 2.8e-53 180.9 0.0 3.5e-53 180.6 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 ORY04379.1 - 2.6e-22 79.5 0.0 3.3e-22 79.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 ORY04379.1 - 1.8e-11 43.8 0.3 4.4e-09 35.9 0.1 2.9 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 ORY04379.1 - 2.3e-11 43.7 0.0 4e-11 42.9 0.0 1.3 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 ORY04379.1 - 5e-10 38.9 0.0 2.1e-09 36.8 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 ORY04379.1 - 1.4e-08 34.3 0.0 9.6e-08 31.5 0.0 2.0 2 0 0 2 2 2 1 Male sterility protein NmrA PF05368.13 ORY04379.1 - 0.2 11.2 0.0 1.3 8.5 0.0 2.0 2 0 0 2 2 2 0 NmrA-like family KR PF08659.10 ORY04379.1 - 0.3 11.0 0.5 16 5.3 0.0 2.4 1 1 1 2 2 2 0 KR domain Ribonuc_L-PSP PF01042.21 ORY04381.1 - 5.2e-12 45.9 0.0 6.2e-12 45.6 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP BT1 PF03092.16 ORY04382.1 - 0.048 11.9 0.3 0.081 11.1 0.3 1.3 1 0 0 1 1 1 0 BT1 family DUF4149 PF13664.6 ORY04382.1 - 0.13 12.5 4.4 1.5 9.2 0.6 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4149) DUF3278 PF11683.8 ORY04382.1 - 0.21 11.7 1.0 0.76 9.9 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3278) DUF4064 PF13273.6 ORY04382.1 - 0.28 11.5 4.5 1.4 9.2 0.5 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF4064) DUF2207 PF09972.9 ORY04382.1 - 0.58 8.8 0.0 0.58 8.8 0.0 2.8 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) PDR_CDR PF06422.12 ORY04382.1 - 0.78 9.7 3.0 55 3.8 0.1 3.7 3 1 0 3 3 3 0 CDR ABC transporter CcmH PF03918.14 ORY04382.1 - 1.7 8.0 3.5 37 3.6 0.0 3.1 3 0 0 3 3 3 0 Cytochrome C biogenesis protein DUF3894 PF13033.6 ORY04382.1 - 2.2 8.4 6.0 0.73 10.0 2.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3894) Hap4_Hap_bind PF10297.9 ORY04384.1 - 3.5e-06 26.9 6.9 7.5e-06 25.9 6.9 1.6 1 0 0 1 1 1 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 bZIP_1 PF00170.21 ORY04384.1 - 0.12 12.5 18.5 0.03 14.4 13.1 2.4 1 1 1 2 2 2 0 bZIP transcription factor Mitofilin PF09731.9 ORY04384.1 - 0.47 9.2 8.6 0.67 8.7 8.6 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein AAA_13 PF13166.6 ORY04384.1 - 0.85 8.2 4.3 1.4 7.5 4.3 1.2 1 0 0 1 1 1 0 AAA domain Spc7 PF08317.11 ORY04384.1 - 1.8 7.4 10.6 2.7 6.8 10.6 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein RTA1 PF04479.13 ORY04386.1 - 1.3e-69 233.9 4.1 1.3e-69 233.9 4.1 1.7 2 0 0 2 2 2 1 RTA1 like protein DUF4328 PF14219.6 ORY04386.1 - 0.044 13.3 0.0 0.044 13.3 0.0 2.3 3 1 0 3 3 3 0 Domain of unknown function (DUF4328) FixQ PF05545.11 ORY04386.1 - 0.9 9.6 4.1 0.44 10.5 0.8 2.3 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ DUF4956 PF16316.5 ORY04386.1 - 1.6 8.3 4.4 0.98 9.1 1.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4956) Glyco_hydro_61 PF03443.14 ORY04387.1 - 3.8e-33 115.2 0.0 4.7e-33 114.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 WD40 PF00400.32 ORY04388.1 - 2.5e-07 31.3 6.4 0.00026 21.7 0.1 4.6 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY04388.1 - 0.00016 21.9 0.0 0.27 11.6 0.0 2.9 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ORY04388.1 - 0.0003 20.7 0.0 0.00055 19.9 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 ORY04388.1 - 0.0027 17.6 1.9 1.5 8.9 0.0 4.1 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Abhydrolase_1 PF00561.20 ORY04389.1 - 3.2e-11 43.4 0.3 1.1e-09 38.3 0.3 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORY04389.1 - 1.2e-05 26.0 0.3 1.7e-05 25.6 0.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 ORY04389.1 - 0.016 14.8 0.0 0.024 14.3 0.0 1.4 1 1 0 1 1 1 0 Putative esterase FSH1 PF03959.13 ORY04389.1 - 0.057 13.1 0.0 0.088 12.5 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) LysM PF01476.20 ORY04390.1 - 1.2e-20 73.3 0.8 1.1e-07 31.8 0.1 3.9 4 0 0 4 4 4 3 LysM domain Glyco_hydro_18 PF00704.28 ORY04392.1 - 6.7e-71 239.6 0.7 1.2e-70 238.7 0.7 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 ORY04392.1 - 8.4e-10 39.0 17.9 8.4e-10 39.0 17.9 5.8 7 1 0 7 7 7 2 Chitin recognition protein SnoaL PF07366.12 ORY04393.1 - 0.059 13.2 0.3 0.56 10.0 0.2 2.0 1 1 1 2 2 2 0 SnoaL-like polyketide cyclase Glyco_transf_34 PF05637.12 ORY04394.1 - 4.9e-08 33.0 0.6 1e-07 31.9 0.6 1.5 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Nucleotid_trans PF03407.16 ORY04394.1 - 3.6e-06 27.1 0.1 1.3e-05 25.2 0.0 1.9 2 0 0 2 2 2 1 Nucleotide-diphospho-sugar transferase DUF273 PF03314.14 ORY04394.1 - 6.1e-06 26.0 0.0 1.1e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF273 PQQ_2 PF13360.6 ORY04447.1 - 6.3e-11 42.3 1.3 0.00025 20.7 0.2 4.0 2 2 2 4 4 4 4 PQQ-like domain PQQ_3 PF13570.6 ORY04447.1 - 2.6e-07 30.9 15.8 0.043 14.3 0.4 6.5 6 1 0 6 6 6 4 PQQ-like domain PQQ PF01011.21 ORY04447.1 - 0.0005 19.9 1.2 4.7 7.3 0.1 4.5 4 0 0 4 4 4 2 PQQ enzyme repeat PS-DH PF14765.6 ORY04448.1 - 4.1e-70 236.4 0.0 6.6e-70 235.7 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase ketoacyl-synt PF00109.26 ORY04448.1 - 4.2e-69 232.9 0.0 1.4e-68 231.2 0.0 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 ORY04448.1 - 1.2e-54 184.9 0.6 2.8e-54 183.8 0.6 1.7 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.21 ORY04448.1 - 5.8e-49 167.3 0.0 1.4e-48 166.1 0.0 1.6 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 ORY04448.1 - 1.9e-35 121.4 0.1 4.8e-35 120.1 0.1 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 ORY04448.1 - 3.8e-20 72.5 0.0 4.9e-19 68.9 0.0 2.8 3 0 0 3 3 2 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 ORY04448.1 - 4.1e-15 56.2 2.3 6.8e-11 42.6 0.1 3.0 3 0 0 3 3 3 2 Ketoacyl-synthetase C-terminal extension Methyltransf_25 PF13649.6 ORY04448.1 - 1.6e-13 51.1 0.0 1.3e-12 48.2 0.0 2.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY04448.1 - 2.6e-12 47.2 0.0 2.6e-11 44.0 0.0 3.0 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 ORY04448.1 - 4.1e-12 46.0 1.2 1.9e-11 43.8 0.2 2.4 3 0 0 3 3 3 1 short chain dehydrogenase Methyltransf_31 PF13847.6 ORY04448.1 - 2.4e-11 43.6 0.0 2.8e-10 40.2 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY04448.1 - 3.1e-10 40.2 0.0 7.7e-10 38.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.26 ORY04448.1 - 3e-08 33.7 0.1 9.9e-07 28.8 0.1 2.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase PP-binding PF00550.25 ORY04448.1 - 9.5e-07 29.1 0.4 7.8e-06 26.2 0.2 2.6 2 0 0 2 2 2 1 Phosphopantetheine attachment site adh_short_C2 PF13561.6 ORY04448.1 - 5.1e-06 26.2 0.4 1.6e-05 24.6 0.4 1.8 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Ubie_methyltran PF01209.18 ORY04448.1 - 5.2e-06 26.0 0.0 1.4e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family ADH_zinc_N_2 PF13602.6 ORY04448.1 - 9.8e-06 26.7 0.0 0.0015 19.6 0.0 3.4 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ORY04448.1 - 0.00017 21.4 0.0 0.0007 19.4 0.0 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Thiolase_N PF00108.23 ORY04448.1 - 0.00082 18.8 0.2 0.002 17.6 0.2 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain MTS PF05175.14 ORY04448.1 - 0.00091 18.8 0.0 0.0033 17.0 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase small domain 3Beta_HSD PF01073.19 ORY04448.1 - 0.0021 17.1 0.1 0.0035 16.4 0.1 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 ORY04448.1 - 0.0036 16.5 0.0 0.0057 15.8 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Methyltransf_33 PF10017.9 ORY04448.1 - 0.0052 16.0 0.0 0.021 14.0 0.0 2.0 2 0 0 2 2 2 1 Histidine-specific methyltransferase, SAM-dependent ACP_syn_III PF08545.10 ORY04448.1 - 0.013 15.4 0.2 0.042 13.7 0.2 1.9 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Methyltransf_2 PF00891.18 ORY04449.1 - 2.8e-20 72.5 0.0 4.6e-20 71.8 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_25 PF13649.6 ORY04449.1 - 0.0015 19.2 0.1 0.0065 17.1 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 ORY04449.1 - 0.0045 16.6 0.0 0.0075 15.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain GidB PF02527.15 ORY04449.1 - 0.094 12.0 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_31 PF13847.6 ORY04449.1 - 0.11 12.3 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Zn_clus PF00172.18 ORY04450.1 - 0.14 12.3 20.1 0.042 14.0 16.1 2.2 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.22 ORY04451.1 - 1.7e-39 135.8 0.0 1.1e-27 97.0 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 ANP PF00212.18 ORY04451.1 - 0.24 11.6 1.6 1.4 9.2 0.4 2.3 2 0 0 2 2 2 0 Atrial natriuretic peptide MFS_1 PF07690.16 ORY04452.1 - 6.8e-36 123.9 53.8 6.8e-36 123.9 53.8 3.1 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 ORY04452.1 - 4e-08 32.2 24.7 7.4e-08 31.3 24.5 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Zn_clus PF00172.18 ORY04454.1 - 5.5e-10 39.2 8.5 7e-10 38.9 8.5 1.1 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MBOAT_2 PF13813.6 ORY04455.1 - 2.7e-21 75.6 0.9 7.3e-21 74.2 0.9 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family FAD_binding_4 PF01565.23 ORY04456.1 - 2.2e-15 56.6 0.0 8.3e-15 54.8 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain Methyltransf_25 PF13649.6 ORY04457.1 - 2.4e-16 60.2 0.0 3.2e-15 56.6 0.0 2.7 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY04457.1 - 1.6e-14 54.3 0.0 9.1e-14 51.9 0.0 2.2 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY04457.1 - 1.3e-12 47.8 0.0 2.1e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORY04457.1 - 3.8e-11 42.8 0.0 8e-11 41.7 0.0 1.6 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 ORY04457.1 - 6.4e-11 42.3 0.0 1.2e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY04457.1 - 1.3e-05 25.9 0.0 4.5e-05 24.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ORY04457.1 - 0.0057 16.2 0.0 0.016 14.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase small domain Methyltr_RsmB-F PF01189.17 ORY04457.1 - 0.098 12.3 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F NAD_binding_6 PF08030.12 ORY04459.1 - 0.029 14.5 0.5 0.093 12.8 0.1 1.8 2 0 0 2 2 2 0 Ferric reductase NAD binding domain TPALS PF18178.1 ORY04459.1 - 0.12 11.8 0.1 2.9 7.3 0.0 2.0 2 0 0 2 2 2 0 TIR- and PNP-associating SLOG family DUF1996 PF09362.10 ORY04460.1 - 2.3e-79 266.7 3.8 2.9e-79 266.3 3.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Sugar_tr PF00083.24 ORY04462.1 - 7.1e-76 255.9 25.5 8.2e-76 255.7 25.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY04462.1 - 4.1e-24 85.2 26.1 3.1e-22 79.0 16.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 ORY04462.1 - 3.1e-06 26.0 22.2 5.5e-05 21.9 7.1 2.5 2 0 0 2 2 2 2 MFS/sugar transport protein MFS_4 PF06779.14 ORY04462.1 - 0.0002 20.8 1.3 0.0002 20.8 1.3 2.2 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB TRI12 PF06609.13 ORY04462.1 - 0.0058 15.1 1.5 0.0058 15.1 1.5 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) YrhK PF14145.6 ORY04462.1 - 0.018 14.9 0.9 0.018 14.9 0.9 3.5 2 1 1 3 3 3 0 YrhK-like protein MerC PF03203.14 ORY04462.1 - 4.5 7.8 11.8 4.2 7.8 3.5 3.1 3 1 0 3 3 3 0 MerC mercury resistance protein DUF4267 PF14087.6 ORY04464.1 - 8e-14 51.7 5.4 1e-13 51.3 5.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) DUF2157 PF09925.9 ORY04464.1 - 1.4 8.7 9.9 0.43 10.4 6.7 1.7 1 1 1 2 2 2 0 Predicted membrane protein (DUF2157) ATP1G1_PLM_MAT8 PF02038.16 ORY04464.1 - 4.6 6.7 6.7 5.2 6.6 0.1 3.0 3 0 0 3 3 3 0 ATP1G1/PLM/MAT8 family DUF4407 PF14362.6 ORY04464.1 - 9.8 5.4 8.6 0.41 10.0 3.3 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) COesterase PF00135.28 ORY04465.1 - 3.7e-83 280.1 0.0 4.5e-83 279.9 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 ORY04465.1 - 1.2e-08 35.1 0.1 2.2e-08 34.2 0.1 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold HET PF06985.11 ORY04466.1 - 6.8e-18 65.4 0.0 1.5e-17 64.3 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Kdo PF06293.14 ORY04467.1 - 9.9e-05 21.8 1.2 0.00017 21.0 0.3 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 ORY04467.1 - 0.039 13.5 0.0 0.07 12.7 0.0 1.4 1 0 0 1 1 1 0 RIO1 family HAD_2 PF13419.6 ORY04468.1 - 4.1e-09 36.8 0.0 2.4e-08 34.2 0.0 1.9 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ORY04468.1 - 0.0018 18.6 0.0 0.076 13.3 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HET PF06985.11 ORY04469.1 - 2e-06 28.2 0.0 2.6e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Peptidase_A4 PF01828.17 ORY04470.1 - 9.8e-41 139.5 12.0 1.1e-40 139.3 12.0 1.0 1 0 0 1 1 1 1 Peptidase A4 family DUF1996 PF09362.10 ORY04471.1 - 1.3e-79 267.4 1.1 1.7e-79 267.2 1.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Lys PF00062.20 ORY04471.1 - 0.066 13.5 0.1 0.18 12.0 0.1 1.7 1 0 0 1 1 1 0 C-type lysozyme/alpha-lactalbumin family Staufen_C PF16482.5 ORY04472.1 - 0.071 13.3 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Staufen C-terminal domain TPR_12 PF13424.6 ORY04473.1 - 4.4e-24 84.6 16.2 3.2e-05 24.1 0.5 7.4 6 1 1 7 7 7 6 Tetratricopeptide repeat TPR_10 PF13374.6 ORY04473.1 - 1.7e-10 40.4 9.5 0.6 10.1 0.2 7.9 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.6 ORY04473.1 - 1.3e-08 34.2 1.7 0.047 13.7 0.0 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 ORY04473.1 - 0.00029 20.8 4.3 2.7 8.4 0.5 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 ORY04473.1 - 0.00073 19.5 14.7 1.1 9.5 0.5 7.7 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_16 PF13432.6 ORY04473.1 - 0.001 19.7 0.2 14 6.5 0.2 6.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 ORY04473.1 - 0.0015 19.0 7.2 43 5.1 0.0 6.5 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_19 PF14559.6 ORY04473.1 - 0.015 15.8 11.0 0.94 10.0 1.2 5.7 5 2 1 6 6 6 0 Tetratricopeptide repeat TBCC_N PF16752.5 ORY04473.1 - 0.02 15.4 1.0 0.096 13.1 0.1 2.5 2 0 0 2 2 2 0 Tubulin-specific chaperone C N-terminal domain TPR_4 PF07721.14 ORY04473.1 - 0.023 15.3 3.2 0.78 10.5 0.4 4.6 4 0 0 4 4 3 0 Tetratricopeptide repeat DUF2225 PF09986.9 ORY04473.1 - 0.11 12.3 0.9 0.57 9.9 0.2 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_1 PF00515.28 ORY04473.1 - 0.37 10.7 0.0 0.37 10.7 0.0 4.4 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF1899 PF08953.11 ORY04474.1 - 4.8e-35 119.2 0.8 1.5e-34 117.7 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 ORY04474.1 - 4.1e-18 65.0 0.1 8.2e-18 64.0 0.1 1.5 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 ORY04474.1 - 1.1e-17 64.1 5.4 5.8e-05 23.8 0.2 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY04474.1 - 4.9e-07 30.0 0.1 0.00093 19.4 0.0 3.5 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 ORY04474.1 - 0.0034 16.4 0.0 0.56 9.1 0.0 2.6 1 1 2 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 ORY04474.1 - 0.0061 15.3 0.1 0.74 8.4 0.1 2.3 1 1 1 2 2 2 2 Nucleoporin Nup120/160 eIF2A PF08662.11 ORY04474.1 - 0.025 14.5 0.0 0.38 10.6 0.0 2.2 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A SlyX PF04102.12 ORY04474.1 - 0.089 13.4 4.4 0.073 13.7 1.8 2.2 2 0 0 2 2 2 0 SlyX TolA_bind_tri PF16331.5 ORY04474.1 - 0.11 12.6 3.7 0.21 11.7 3.7 1.3 1 0 0 1 1 1 0 TolA binding protein trimerisation PKcGMP_CC PF16808.5 ORY04474.1 - 0.13 12.1 5.5 0.36 10.7 5.5 1.7 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase PEX11 PF05648.14 ORY04476.1 - 7.2e-09 35.4 0.0 1.3e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Sugar_tr PF00083.24 ORY04477.1 - 6.6e-87 292.2 28.1 7.9e-87 292.0 28.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY04477.1 - 4.4e-17 62.1 68.2 3.3e-15 55.9 36.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TAL_FSA PF00923.19 ORY04478.1 - 3.6e-36 125.0 0.0 1.1e-35 123.4 0.0 1.6 1 1 1 2 2 2 1 Transaldolase/Fructose-6-phosphate aldolase HLH PF00010.26 ORY04479.1 - 1.2e-06 28.4 1.4 2.5e-06 27.3 1.4 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain NmrA PF05368.13 ORY04480.1 - 1.2e-39 136.3 0.0 2e-39 135.6 0.0 1.3 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ORY04480.1 - 2.7e-13 50.2 0.0 4.5e-13 49.5 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 ORY04480.1 - 0.00032 20.2 0.0 0.00044 19.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 ORY04480.1 - 0.037 13.0 0.0 0.048 12.7 0.0 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.18 ORY04480.1 - 0.063 13.5 0.0 0.49 10.7 0.0 2.1 2 0 0 2 2 2 0 TrkA-N domain DXP_reductoisom PF02670.16 ORY04480.1 - 0.083 13.6 0.1 0.55 10.9 0.2 2.3 2 1 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Pyr_redox_2 PF07992.14 ORY04482.1 - 4.8e-27 94.9 0.0 6.9e-27 94.4 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORY04482.1 - 1.4e-11 44.8 0.1 8e-10 39.2 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ORY04482.1 - 3e-05 23.3 0.0 0.0012 18.1 0.0 2.1 1 1 1 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 ORY04482.1 - 0.00013 21.4 0.0 0.0032 16.8 0.0 2.1 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 ORY04482.1 - 0.00034 19.8 0.2 0.12 11.4 0.0 2.4 2 1 1 3 3 3 2 Lycopene cyclase protein NAD_binding_9 PF13454.6 ORY04482.1 - 0.00039 20.4 0.6 4 7.4 0.0 4.0 3 1 0 4 4 4 1 FAD-NAD(P)-binding DAO PF01266.24 ORY04482.1 - 0.0068 16.0 0.8 6.3 6.3 0.1 3.3 3 1 1 4 4 4 2 FAD dependent oxidoreductase ApbA PF02558.16 ORY04482.1 - 0.028 14.1 0.0 5.4 6.6 0.0 2.8 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA Ldh_1_N PF00056.23 ORY04482.1 - 0.12 12.5 0.0 11 6.2 0.0 3.0 2 1 1 3 3 3 0 lactate/malate dehydrogenase, NAD binding domain TauD PF02668.16 ORY04483.1 - 2.9e-41 142.0 1.1 3.3e-41 141.9 1.1 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family PrpF PF04303.13 ORY04536.1 - 2e-22 79.7 0.3 4.8e-15 55.4 0.1 2.2 2 0 0 2 2 2 2 PrpF protein Fungal_trans PF04082.18 ORY04536.1 - 6.8e-21 74.5 0.2 1e-20 73.9 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF2985 PF11204.8 ORY04537.1 - 2.5e-25 88.4 0.7 2.5e-25 88.4 0.7 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF2985) Ubiq-assoc PF09145.10 ORY04537.1 - 0.3 11.1 1.2 0.49 10.4 1.2 1.3 1 0 0 1 1 1 0 Ubiquitin-associated Glyco_transf_28 PF03033.20 ORY04538.1 - 1.7e-18 67.0 0.5 2.1e-12 47.2 0.1 2.6 2 0 0 2 2 2 2 Glycosyltransferase family 28 N-terminal domain ATG_C PF09333.11 ORY04538.1 - 3.3e-05 24.2 0.0 0.00011 22.5 0.0 1.8 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain UDPGT PF00201.18 ORY04538.1 - 4.2e-05 22.5 0.0 6.4e-05 21.9 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 ORY04538.1 - 0.012 15.6 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain Abhydrolase_4 PF08386.10 ORY04539.1 - 1e-17 64.1 0.0 2.3e-17 63.0 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.20 ORY04539.1 - 3.4e-14 53.1 0.0 3.2e-11 43.4 0.0 2.4 2 1 0 2 2 2 2 alpha/beta hydrolase fold ESSS PF10183.9 ORY04539.1 - 0.058 13.6 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Peptidase_S28 PF05577.12 ORY04539.1 - 0.064 12.0 0.0 0.091 11.5 0.0 1.1 1 0 0 1 1 1 0 Serine carboxypeptidase S28 Hydrolase_4 PF12146.8 ORY04539.1 - 0.1 11.8 0.0 3.2 7.0 0.0 2.3 2 0 0 2 2 2 0 Serine aminopeptidase, S33 DUF4419 PF14388.6 ORY04540.1 - 9.2e-103 343.8 0.0 1.8e-102 342.9 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4419) WWE PF02825.20 ORY04540.1 - 0.027 15.0 0.0 0.07 13.7 0.0 1.7 1 0 0 1 1 1 0 WWE domain His_Phos_2 PF00328.22 ORY04541.1 - 1.3e-23 84.0 0.0 1.6e-23 83.7 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) His_Phos_1 PF00300.22 ORY04541.1 - 0.23 11.1 0.0 0.89 9.2 0.0 1.8 2 0 0 2 2 2 0 Histidine phosphatase superfamily (branch 1) Rhodanese_C PF12368.8 ORY04542.1 - 3.7e-13 49.6 8.9 7.9e-13 48.6 8.9 1.6 1 0 0 1 1 1 1 Rhodanase C-terminal Rhodanese PF00581.20 ORY04542.1 - 0.0038 17.7 0.1 0.011 16.2 0.1 1.7 1 1 0 1 1 1 1 Rhodanese-like domain p450 PF00067.22 ORY04544.1 - 3.6e-56 190.8 0.0 4.4e-56 190.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3983 PF13137.6 ORY04544.1 - 0.077 12.8 0.1 0.19 11.5 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3983) Shisa PF13908.6 ORY04545.1 - 0.0014 18.9 0.1 0.0019 18.5 0.1 1.3 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator DUF2207 PF09972.9 ORY04545.1 - 0.0035 16.2 0.0 0.0035 16.2 0.0 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) AA_permease_2 PF13520.6 ORY04546.1 - 1.3e-60 205.4 31.3 2e-59 201.5 18.8 2.0 2 0 0 2 2 2 2 Amino acid permease AA_permease PF00324.21 ORY04546.1 - 7.4e-13 47.9 15.3 7.4e-13 47.9 15.3 1.9 2 0 0 2 2 2 1 Amino acid permease DUF1700 PF08006.11 ORY04546.1 - 1 8.8 3.7 20 4.7 0.3 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1700) Gpr1_Fun34_YaaH PF01184.19 ORY04547.1 - 9.1e-91 303.1 16.7 1e-90 302.9 16.7 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DHHA2 PF02833.14 ORY04548.1 - 3.4e-15 56.5 0.1 5.5e-15 55.8 0.1 1.4 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.20 ORY04548.1 - 1.4e-08 34.8 0.0 3.5e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 DHH family ABM PF03992.16 ORY04549.1 - 1e-09 38.4 0.0 1.3e-09 38.1 0.0 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase zf-C2H2 PF00096.26 ORY04550.1 - 4.4 8.0 11.1 3.2 8.4 1.4 3.3 2 0 0 2 2 2 0 Zinc finger, C2H2 type Fungal_trans PF04082.18 ORY04551.1 - 1.4e-11 43.9 0.0 3e-11 42.8 0.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY04551.1 - 2.5e-07 30.7 13.2 5.3e-07 29.6 13.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_3 PF01494.19 ORY04552.1 - 2.9e-27 95.8 0.0 1.9e-17 63.5 0.0 2.0 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 ORY04552.1 - 6.7e-06 26.2 0.1 1.6e-05 25.0 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ORY04552.1 - 2.5e-05 24.0 1.7 0.0013 18.4 0.9 2.2 1 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 ORY04552.1 - 2.6e-05 23.5 0.1 3.9e-05 22.9 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 ORY04552.1 - 0.0067 15.7 0.1 0.016 14.5 0.1 1.5 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORY04552.1 - 0.033 14.8 0.0 0.11 13.0 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 ORY04552.1 - 0.13 11.3 0.0 1.1 8.3 0.0 2.0 2 0 0 2 2 2 0 Squalene epoxidase Trp_halogenase PF04820.14 ORY04552.1 - 0.15 10.9 0.1 14 4.3 0.1 2.8 3 0 0 3 3 3 0 Tryptophan halogenase GIDA PF01134.22 ORY04552.1 - 0.17 11.0 0.1 0.24 10.5 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A HI0933_like PF03486.14 ORY04552.1 - 0.18 10.5 0.1 0.41 9.3 0.1 1.6 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_3 PF13738.6 ORY04552.1 - 0.22 10.8 0.5 0.94 8.7 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_10 PF13460.6 ORY04553.1 - 6.6e-35 120.7 0.1 7.5e-35 120.5 0.1 1.0 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 ORY04553.1 - 8.9e-08 32.0 0.3 4.6e-07 29.6 0.1 2.1 1 1 1 2 2 2 1 NmrA-like family Epimerase PF01370.21 ORY04553.1 - 2.6e-06 27.1 0.0 3.6e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 ORY04553.1 - 1e-05 25.7 0.1 1.8e-05 25.0 0.1 1.5 1 1 0 1 1 1 1 TrkA-N domain DapB_N PF01113.20 ORY04553.1 - 0.0018 18.4 0.0 0.0033 17.5 0.0 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus ApbA PF02558.16 ORY04553.1 - 0.0054 16.4 0.0 0.0077 15.9 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Glyco_trans_4_4 PF13579.6 ORY04553.1 - 0.0077 16.7 0.0 0.016 15.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain F420_oxidored PF03807.17 ORY04553.1 - 0.0078 16.8 0.1 0.014 16.0 0.1 1.6 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 ORY04553.1 - 0.012 15.9 0.0 0.018 15.3 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain GDP_Man_Dehyd PF16363.5 ORY04553.1 - 0.014 14.8 0.0 0.019 14.3 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 ORY04553.1 - 0.015 14.4 0.0 0.021 13.9 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain NAD_binding_4 PF07993.12 ORY04553.1 - 0.037 13.2 0.0 0.095 11.9 0.0 1.6 2 0 0 2 2 2 0 Male sterility protein Shikimate_DH PF01488.20 ORY04553.1 - 0.13 12.3 0.6 0.52 10.4 0.6 1.9 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase DUF4470 PF14737.6 ORY04554.1 - 3.1e-12 46.5 0.3 2.3e-10 40.5 0.3 2.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4470) MFS_1 PF07690.16 ORY04556.1 - 4.5e-41 140.9 11.1 1.6e-25 89.8 0.3 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY04556.1 - 4.8e-13 48.8 6.2 3.4e-10 39.4 0.5 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter UDPGP PF01704.18 ORY04557.1 - 3e-191 635.5 0.0 3.4e-191 635.3 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase CAF1C_H4-bd PF12265.8 ORY04558.1 - 0.0039 17.4 0.3 0.0071 16.6 0.3 1.5 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex FolB PF02152.18 ORY04559.1 - 1.5e-32 112.5 0.1 5.9e-20 71.9 0.0 2.1 2 0 0 2 2 2 2 Dihydroneopterin aldolase STI1 PF17830.1 ORY04560.1 - 2.1e-17 62.8 2.6 4.2e-17 61.8 2.6 1.5 1 0 0 1 1 1 1 STI1 domain TPR_1 PF00515.28 ORY04560.1 - 2.2e-10 39.9 2.4 5.9e-05 22.7 0.2 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 ORY04560.1 - 3e-07 30.0 0.8 0.0025 17.8 0.1 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 ORY04560.1 - 1.9e-06 27.4 1.2 0.0017 18.0 0.1 2.3 1 1 1 2 2 2 2 TPR repeat TPR_8 PF13181.6 ORY04560.1 - 7.8e-05 22.6 0.4 0.018 15.2 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 ORY04560.1 - 0.00035 20.3 0.1 0.0045 16.8 0.0 2.2 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 ORY04560.1 - 0.00092 19.5 0.5 0.057 13.7 0.1 2.1 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.6 ORY04560.1 - 0.0012 18.8 0.4 0.077 13.1 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat DUF3391 PF11871.8 ORY04560.1 - 0.0034 17.9 1.2 0.0056 17.2 1.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3391) TPR_16 PF13432.6 ORY04560.1 - 0.0088 16.7 0.1 0.062 14.0 0.1 2.2 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 ORY04560.1 - 0.012 16.4 0.0 2.3 9.2 0.0 2.7 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 ORY04560.1 - 0.012 16.1 0.0 0.029 14.9 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF4652 PF15525.6 ORY04560.1 - 0.044 13.6 2.3 0.059 13.2 2.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4652) TPR_3 PF07720.12 ORY04560.1 - 0.045 13.7 1.3 8.4 6.5 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_MalT PF17874.1 ORY04560.1 - 0.066 12.6 0.0 0.088 12.2 0.0 1.1 1 0 0 1 1 1 0 MalT-like TPR region TPR_6 PF13174.6 ORY04560.1 - 0.14 12.8 0.2 12 6.8 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Trypan_PARP PF05887.11 ORY04560.1 - 0.14 12.1 16.3 0.23 11.4 16.3 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) TPR_1 PF00515.28 ORY04561.1 - 5.7e-10 38.6 0.3 0.0017 18.1 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 ORY04561.1 - 2.4e-05 24.1 0.3 0.046 13.8 0.4 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 ORY04561.1 - 0.00056 20.4 0.3 0.0015 19.0 0.2 1.8 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 ORY04561.1 - 0.0022 18.2 0.0 0.19 12.2 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 ORY04561.1 - 0.0045 17.1 0.7 0.16 12.3 0.2 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 ORY04561.1 - 0.0047 16.6 0.0 0.14 11.8 0.0 2.3 2 0 0 2 2 2 1 TPR repeat ANAPC3 PF12895.7 ORY04561.1 - 0.011 16.0 0.1 0.016 15.4 0.1 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 ANAPC8 PF04049.13 ORY04561.1 - 0.023 14.8 0.4 0.04 14.0 0.4 1.4 1 1 0 1 1 1 0 Anaphase promoting complex subunit 8 / Cdc23 TPR_14 PF13428.6 ORY04561.1 - 0.04 14.7 1.2 1.4 10.0 0.1 3.2 3 1 1 4 4 4 0 Tetratricopeptide repeat DUF384 PF04064.13 ORY04561.1 - 0.044 13.7 1.6 0.079 12.8 1.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF384) ProQ PF04352.13 ORY04561.1 - 0.17 11.8 2.7 0.24 11.3 2.7 1.1 1 0 0 1 1 1 0 ProQ/FINO family DUF4094 PF13334.6 ORY04562.1 - 0.23 11.9 2.6 0.19 12.2 0.6 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) RIC3 PF15361.6 ORY04562.1 - 0.23 11.8 1.0 0.34 11.3 0.2 1.7 2 0 0 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 bZIP_1 PF00170.21 ORY04562.1 - 0.63 10.2 6.7 1.1 9.4 6.7 1.3 1 0 0 1 1 1 0 bZIP transcription factor Methyltransf_31 PF13847.6 ORY04563.1 - 3.1e-31 108.2 0.0 3.9e-31 107.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY04563.1 - 7.1e-23 81.1 0.0 1.9e-22 79.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY04563.1 - 9.4e-21 74.3 0.0 2.4e-20 73.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORY04563.1 - 4e-18 65.6 0.0 1.5e-17 63.7 0.0 1.8 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 ORY04563.1 - 2.3e-12 47.1 0.0 3.4e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY04563.1 - 7.5e-11 42.7 0.0 1.1e-10 42.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 ORY04563.1 - 1.4e-09 38.0 0.0 3.1e-09 36.9 0.0 1.5 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 ORY04563.1 - 6e-09 35.7 0.0 8.4e-09 35.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_2 PF00891.18 ORY04563.1 - 3.6e-06 26.4 0.0 4.2e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase domain UPF0020 PF01170.18 ORY04563.1 - 9.9e-06 25.4 0.0 1.4e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 MTS PF05175.14 ORY04563.1 - 1.3e-05 24.8 0.0 2.4e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 ORY04563.1 - 0.00016 21.1 0.0 0.00019 20.8 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.6 ORY04563.1 - 0.00024 21.1 0.0 0.00032 20.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 ORY04563.1 - 0.001 19.0 0.0 0.0015 18.4 0.0 1.3 1 1 0 1 1 1 1 Hypothetical methyltransferase TehB PF03848.14 ORY04563.1 - 0.005 16.3 0.0 0.0069 15.8 0.0 1.1 1 0 0 1 1 1 1 Tellurite resistance protein TehB DOT1 PF08123.13 ORY04563.1 - 0.0059 16.2 0.2 0.024 14.2 0.2 2.0 1 1 0 1 1 1 1 Histone methylation protein DOT1 FtsJ PF01728.19 ORY04563.1 - 0.01 16.0 0.0 0.02 15.0 0.0 1.4 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_18 PF12847.7 ORY04563.1 - 0.02 14.8 0.0 0.03 14.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_29 PF03141.16 ORY04563.1 - 0.021 13.4 0.0 0.026 13.1 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_4 PF02390.17 ORY04563.1 - 0.045 13.2 0.0 0.25 10.8 0.0 1.9 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_9 PF08003.11 ORY04563.1 - 0.11 11.4 0.0 5.5 5.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) GidB PF02527.15 ORY04563.1 - 0.13 11.6 0.1 0.58 9.5 0.1 1.9 1 1 0 1 1 1 0 rRNA small subunit methyltransferase G CheR PF01739.18 ORY04563.1 - 0.15 11.6 0.0 1.7 8.1 0.0 2.2 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain NNMT_PNMT_TEMT PF01234.17 ORY04563.1 - 0.15 11.2 0.0 11 5.1 0.0 2.2 1 1 1 2 2 2 0 NNMT/PNMT/TEMT family AltA1 PF16541.5 ORY04564.1 - 3.7e-17 63.2 1.7 4.6e-17 62.9 1.7 1.1 1 0 0 1 1 1 1 Alternaria alternata allergen 1 Peptidase_M35 PF02102.15 ORY04565.1 - 7.1e-69 232.4 10.2 7.8e-69 232.2 10.2 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.6 ORY04565.1 - 6.6e-40 137.0 1.7 6.6e-40 137.0 1.7 1.5 2 0 0 2 2 2 1 Lysine-specific metallo-endopeptidase HRXXH PF13933.6 ORY04565.1 - 2.1e-05 24.2 1.1 3.4e-05 23.5 1.1 1.3 1 0 0 1 1 1 1 Putative peptidase family DUF3810 PF12725.7 ORY04565.1 - 0.014 14.8 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) RTX_C PF08339.10 ORY04565.1 - 0.05 13.7 1.1 0.16 12.1 0.5 2.0 1 1 1 2 2 2 0 RTX C-terminal domain Cu_bind_like PF02298.17 ORY04566.1 - 0.026 14.6 0.5 0.14 12.2 0.5 2.0 1 1 0 1 1 1 0 Plastocyanin-like domain p450 PF00067.22 ORY04567.1 - 3.3e-56 191.0 0.0 4.1e-56 190.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HET PF06985.11 ORY04568.1 - 1.8e-33 115.9 0.1 2.7e-33 115.4 0.1 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Glyco_hydro_61 PF03443.14 ORY04569.1 - 9.3e-08 32.3 0.0 1e-07 32.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 C2 PF00168.30 ORY04571.1 - 1.5e-79 262.9 0.1 9.7e-22 77.2 0.0 5.5 5 0 0 5 5 5 5 C2 domain SMP_LBD PF17047.5 ORY04571.1 - 0.011 15.2 0.0 0.054 13.0 0.0 2.0 1 1 0 1 1 1 0 Synaptotagmin-like mitochondrial-lipid-binding domain MLVIN_C PF18697.1 ORY04571.1 - 0.09 12.9 0.2 2.4 8.3 0.1 2.6 2 0 0 2 2 2 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain p450 PF00067.22 ORY04572.1 - 2e-58 198.3 0.0 2.5e-58 197.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_S9 PF00326.21 ORY04573.1 - 3.2e-47 160.7 0.6 5.6e-47 160.0 0.6 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family PD40 PF07676.12 ORY04573.1 - 5.3e-05 23.0 0.0 0.00085 19.2 0.0 3.0 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat Glyco_hydro_61 PF03443.14 ORY04574.1 - 2.1e-55 187.9 0.1 2.6e-55 187.6 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DSPc PF00782.20 ORY04575.1 - 4.2e-24 84.9 0.0 5.4e-24 84.5 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 ORY04575.1 - 0.011 15.3 0.0 0.014 15.0 0.0 1.1 1 0 0 1 1 1 0 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 ORY04575.1 - 0.039 14.1 0.2 0.088 12.9 0.1 1.6 1 1 1 2 2 2 0 Inositol hexakisphosphate Peptidase_C14 PF00656.22 ORY04576.1 - 2.1e-41 142.5 0.0 2.7e-41 142.2 0.0 1.1 1 0 0 1 1 1 1 Caspase domain GST_N PF02798.20 ORY04577.1 - 1.9e-12 47.3 0.0 4.8e-12 46.1 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 ORY04577.1 - 3.4e-12 46.6 0.0 7e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 ORY04577.1 - 2e-11 44.0 0.0 4.1e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 ORY04577.1 - 6e-10 39.2 0.1 8.5e-10 38.7 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 ORY04577.1 - 1.7e-06 28.1 0.1 2.8e-06 27.4 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 ORY04577.1 - 2.7e-06 27.3 0.2 7.8e-06 25.8 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 ORY04577.1 - 0.14 12.7 0.0 0.28 11.8 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 ORY04577.1 - 0.15 12.9 0.0 0.35 11.6 0.0 1.7 1 1 0 1 1 1 0 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 ORY04577.1 - 0.16 11.8 0.0 0.32 10.8 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Epimerase PF01370.21 ORY04579.1 - 8.2e-16 58.2 0.1 2.2e-15 56.8 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 ORY04579.1 - 9.1e-13 48.5 0.1 1.3e-12 48.0 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 ORY04579.1 - 6.6e-11 41.7 0.0 1.1e-10 41.0 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 ORY04579.1 - 1.2e-08 34.8 0.0 2.2e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 ORY04579.1 - 7.5e-08 31.8 0.0 0.00057 19.1 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.15 ORY04579.1 - 0.00011 21.4 0.1 0.00017 20.8 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 ORY04579.1 - 0.0008 19.0 0.1 0.0013 18.3 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.25 ORY04579.1 - 0.0067 15.9 0.1 0.021 14.3 0.1 2.0 2 1 0 2 2 2 1 short chain dehydrogenase RmlD_sub_bind PF04321.17 ORY04579.1 - 0.019 14.1 0.1 0.15 11.1 0.0 2.1 2 0 0 2 2 2 0 RmlD substrate binding domain EthD PF07110.11 ORY04580.1 - 1.5e-09 38.8 0.1 1.8e-09 38.6 0.1 1.1 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 ORY04580.1 - 0.077 13.5 0.0 0.25 11.8 0.0 1.7 1 1 0 1 1 1 0 Methylmuconolactone methyl-isomerase GMC_oxred_N PF00732.19 ORY04581.1 - 1.3e-65 221.8 0.0 1.8e-65 221.2 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 ORY04581.1 - 6.4e-32 111.1 0.0 1.1e-31 110.3 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 ORY04581.1 - 3.5e-06 26.3 0.8 5.3e-06 25.7 0.8 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 ORY04581.1 - 0.00028 20.1 2.5 0.028 13.5 1.5 2.1 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.17 ORY04581.1 - 0.0066 15.7 0.7 0.011 15.0 0.2 1.6 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 ORY04581.1 - 0.019 15.2 0.7 0.086 13.1 0.3 2.4 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 ORY04581.1 - 0.097 11.5 0.3 0.15 10.9 0.3 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox_2 PF07992.14 ORY04581.1 - 0.11 11.7 0.1 0.19 10.9 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ORY04581.1 - 0.15 11.6 2.7 0.13 11.8 1.0 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.14 ORY04581.1 - 0.4 9.3 0.8 0.89 8.2 0.6 1.7 2 0 0 2 2 2 0 HI0933-like protein CVNH PF08881.10 ORY04582.1 - 7.6e-28 97.2 0.2 8.4e-28 97.0 0.2 1.0 1 0 0 1 1 1 1 CVNH domain ETX_MTX2 PF03318.13 ORY04652.1 - 0.03 14.1 1.0 0.04 13.7 1.0 1.1 1 0 0 1 1 1 0 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 AAA PF00004.29 ORY04653.1 - 1.3e-19 70.9 0.0 2.9e-19 69.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 ORY04653.1 - 0.00023 21.6 0.6 0.00079 19.9 0.1 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 ORY04653.1 - 0.00037 20.8 1.9 0.067 13.5 0.0 3.3 3 1 1 4 4 3 1 AAA domain AAA_19 PF13245.6 ORY04653.1 - 0.00062 20.1 0.0 0.18 12.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 ORY04653.1 - 0.0016 18.5 0.0 0.0038 17.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 ORY04653.1 - 0.0017 18.1 0.1 0.31 10.7 0.2 3.4 2 1 0 2 2 2 1 AAA domain AAA_2 PF07724.14 ORY04653.1 - 0.0022 18.2 0.0 0.0071 16.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) NACHT PF05729.12 ORY04653.1 - 0.023 14.6 0.1 2 8.3 0.0 2.4 2 0 0 2 2 2 0 NACHT domain Zot PF05707.12 ORY04653.1 - 0.025 14.2 0.0 0.17 11.5 0.0 2.3 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) AAA_18 PF13238.6 ORY04653.1 - 0.031 14.8 0.4 0.21 12.1 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.6 ORY04653.1 - 0.034 14.3 0.2 0.16 12.1 0.0 2.4 2 1 0 2 2 2 0 AAA domain ParA PF10609.9 ORY04653.1 - 0.049 13.1 0.0 0.11 11.9 0.0 1.5 2 0 0 2 2 2 0 NUBPL iron-transfer P-loop NTPase RuvB_N PF05496.12 ORY04653.1 - 0.08 12.7 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain NTPase_1 PF03266.15 ORY04653.1 - 0.11 12.5 0.0 0.38 10.6 0.0 2.1 2 0 0 2 2 2 0 NTPase ATPase PF06745.13 ORY04653.1 - 0.11 11.8 0.4 0.48 9.7 0.1 2.2 3 0 0 3 3 3 0 KaiC AAA_7 PF12775.7 ORY04653.1 - 0.18 11.3 0.0 1.1 8.7 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region Mg_chelatase PF01078.21 ORY04653.1 - 0.19 11.1 0.0 0.41 10.0 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI HET PF06985.11 ORY04654.1 - 6.2e-27 94.7 0.0 1.2e-26 93.8 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) B3_4 PF03483.17 ORY04655.1 - 8.2e-10 38.6 0.0 1.9e-07 30.9 0.0 2.1 1 1 0 1 1 1 1 B3/4 domain FMN_bind_2 PF04299.12 ORY04656.1 - 2.3e-36 125.1 0.2 8.2e-24 84.2 0.0 2.0 1 1 1 2 2 2 2 Putative FMN-binding domain PEP-utilisers_N PF05524.13 ORY04657.1 - 0.06 13.5 3.5 0.17 12.1 3.5 1.7 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal DUF2163 PF09931.9 ORY04657.1 - 0.069 13.4 0.1 0.21 11.8 0.1 1.8 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2163) MRFAP1 PF15155.6 ORY04659.1 - 0.056 14.0 3.1 0.086 13.4 3.1 1.3 1 0 0 1 1 1 0 MORF4 family-associated protein1 DUF3391 PF11871.8 ORY04659.1 - 0.073 13.6 1.2 0.094 13.3 1.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) Macoilin PF09726.9 ORY04659.1 - 0.5 8.9 5.5 0.6 8.6 5.5 1.1 1 0 0 1 1 1 0 Macoilin family AA_permease_2 PF13520.6 ORY04660.1 - 5.3e-22 78.2 47.1 9.4e-21 74.1 47.1 2.0 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ORY04660.1 - 8.8e-14 50.9 40.5 8.8e-12 44.4 13.7 2.1 1 1 1 2 2 2 2 Amino acid permease DUF3506 PF12014.8 ORY04663.1 - 1.5e-51 174.1 0.0 1.6e-50 170.7 0.0 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF3506) F-box PF00646.33 ORY04663.1 - 2.7e-08 33.5 0.7 5.9e-08 32.4 0.7 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 ORY04663.1 - 2.1e-07 30.7 0.9 4.8e-07 29.6 0.9 1.7 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 ORY04663.1 - 0.12 12.3 0.3 3.1 7.7 0.4 2.4 2 0 0 2 2 2 0 F-box Iso_dh PF00180.20 ORY04664.1 - 5.4e-96 321.8 0.0 7.6e-96 321.3 0.0 1.2 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Rabaptin PF03528.15 ORY04664.1 - 0.087 11.5 0.1 0.12 11.0 0.1 1.1 1 0 0 1 1 1 0 Rabaptin DUF1769 PF08588.10 ORY04665.1 - 1.1e-22 79.9 0.1 2.1e-22 79.0 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) Dioxygenase_C PF00775.21 ORY04666.1 - 9.8e-07 28.4 0.1 1.8e-06 27.5 0.1 1.4 1 0 0 1 1 1 1 Dioxygenase BNR_2 PF13088.6 ORY04667.1 - 0.00019 20.8 0.7 0.0046 16.3 0.2 2.4 1 1 2 3 3 3 3 BNR repeat-like domain Glyco_hydro_43 PF04616.14 ORY04667.1 - 0.0015 18.0 0.1 0.03 13.6 0.0 2.3 1 1 1 2 2 2 1 Glycosyl hydrolases family 43 BNR PF02012.20 ORY04667.1 - 0.006 16.4 0.9 4.2 7.8 0.3 3.3 2 0 0 2 2 2 2 BNR/Asp-box repeat FA_desaturase PF00487.24 ORY04668.1 - 1.7e-09 37.9 22.7 1.7e-09 37.9 22.7 1.7 1 1 1 2 2 2 1 Fatty acid desaturase ALC PF17527.2 ORY04668.1 - 0.061 13.0 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Phage ALC protein DUF1661 PF07877.11 ORY04668.1 - 0.068 12.9 0.2 0.17 11.6 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1661) FAD_binding_4 PF01565.23 ORY04669.1 - 4.4e-15 55.6 0.0 7.7e-15 54.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain SLT PF01464.20 ORY04670.1 - 0.0016 18.1 0.0 0.0032 17.1 0.0 1.5 1 1 0 1 1 1 1 Transglycosylase SLT domain BBS2_N PF14781.6 ORY04670.1 - 0.1 12.5 0.0 2.6 8.0 0.0 2.6 2 1 1 3 3 3 0 Ciliary BBSome complex subunit 2, N-terminal Lactonase PF10282.9 ORY04670.1 - 0.14 11.4 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller RRS1 PF04939.12 ORY04673.1 - 0.2 11.5 0.5 0.37 10.6 0.5 1.3 1 0 0 1 1 1 0 Ribosome biogenesis regulatory protein (RRS1) zf-C2H2_4 PF13894.6 ORY04674.1 - 0.0071 17.1 5.9 0.0071 17.1 5.9 2.6 2 0 0 2 2 2 1 C2H2-type zinc finger zf-BED PF02892.15 ORY04674.1 - 0.13 12.3 13.6 0.14 12.2 4.1 2.5 2 0 0 2 2 2 0 BED zinc finger zf-C2H2 PF00096.26 ORY04674.1 - 0.16 12.5 16.1 0.9 10.1 6.6 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type SDA1 PF05285.12 ORY04675.1 - 0.01 15.3 24.6 0.011 15.2 24.6 1.1 1 0 0 1 1 1 1 SDA1 BUD22 PF09073.10 ORY04675.1 - 0.03 13.7 16.7 0.031 13.6 16.7 1.1 1 0 0 1 1 1 0 BUD22 Presenilin PF01080.17 ORY04675.1 - 0.095 11.5 15.2 0.11 11.2 15.2 1.1 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 ORY04675.1 - 0.13 10.6 16.5 0.15 10.4 16.5 1.1 1 0 0 1 1 1 0 CDC45-like protein PA26 PF04636.13 ORY04675.1 - 0.29 10.0 12.8 0.33 9.8 12.8 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) TP53IP5 PF15331.6 ORY04675.1 - 0.32 11.1 9.3 0.4 10.8 9.3 1.2 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 DUF4045 PF13254.6 ORY04675.1 - 0.42 10.2 9.4 0.51 9.9 9.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) SLC12 PF03522.15 ORY04675.1 - 0.44 9.5 13.7 0.5 9.3 13.7 1.1 1 0 0 1 1 1 0 Solute carrier family 12 CCSAP PF15748.5 ORY04675.1 - 0.51 10.5 12.9 0.71 10.0 12.9 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Neur_chan_memb PF02932.16 ORY04675.1 - 0.61 10.1 5.6 0.83 9.7 5.6 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Nop14 PF04147.12 ORY04675.1 - 1.1 7.3 28.9 1.4 7.0 28.9 1.0 1 0 0 1 1 1 0 Nop14-like family Hid1 PF12722.7 ORY04675.1 - 1.2 7.2 15.3 1.3 7.0 15.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein LAP1C PF05609.12 ORY04675.1 - 1.3 8.0 13.7 1.7 7.6 13.7 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Paramyxo_ncap PF00973.19 ORY04675.1 - 1.6 7.6 12.5 1.9 7.3 12.5 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Raftlin PF15250.6 ORY04675.1 - 1.8 7.2 10.8 2.1 7.0 10.8 1.0 1 0 0 1 1 1 0 Raftlin Trypan_PARP PF05887.11 ORY04675.1 - 3.7 7.5 36.3 3.1 7.8 26.3 2.1 1 1 1 2 2 2 0 Procyclic acidic repetitive protein (PARP) Membralin PF09746.9 ORY04675.1 - 8.3 5.3 12.9 9.1 5.2 12.9 1.1 1 0 0 1 1 1 0 Tumour-associated protein Amnionless PF14828.6 ORY04676.1 - 0.18 10.6 0.0 0.19 10.5 0.0 1.1 1 0 0 1 1 1 0 Amnionless HemY_N PF07219.13 ORY04676.1 - 0.18 12.0 2.3 0.27 11.4 2.3 1.3 1 0 0 1 1 1 0 HemY protein N-terminus OAD_gamma PF04277.13 ORY04676.1 - 0.23 12.1 0.4 0.32 11.6 0.4 1.2 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Rootletin PF15035.6 ORY04677.1 - 0.009 16.0 7.8 0.009 16.0 7.8 8.6 3 1 5 8 8 8 2 Ciliary rootlet component, centrosome cohesion DivIC PF04977.15 ORY04677.1 - 0.01 15.6 0.7 0.01 15.6 0.7 15.2 6 5 10 17 17 17 0 Septum formation initiator Ost5 PF05251.12 ORY04678.1 - 3.3 8.0 6.9 3 8.2 0.6 2.8 2 0 0 2 2 2 0 Oligosaccharyltransferase subunit 5 FAD_binding_4 PF01565.23 ORY04679.1 - 1.4e-15 57.2 0.0 2.4e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain adh_short PF00106.25 ORY04680.1 - 1.4e-05 24.7 0.0 2.1e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORY04680.1 - 0.0016 18.4 0.0 0.0029 17.5 0.0 1.4 1 0 0 1 1 1 1 KR domain THDPS_M PF14789.6 ORY04680.1 - 0.064 13.4 0.0 0.28 11.3 0.0 2.1 1 0 0 1 1 1 0 Tetrahydrodipicolinate N-succinyltransferase middle Semialdhyde_dh PF01118.24 ORY04680.1 - 0.11 13.0 0.0 0.26 11.8 0.0 1.7 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Abhydrolase_6 PF12697.7 ORY04681.1 - 4.5e-08 34.0 0.0 5.7e-08 33.6 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORY04681.1 - 1.9e-05 24.1 0.0 3.9e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 LIP PF03583.14 ORY04681.1 - 0.00015 21.2 0.1 0.00031 20.2 0.1 1.5 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_1 PF00561.20 ORY04681.1 - 0.003 17.2 0.2 0.015 15.0 0.1 2.0 2 1 0 2 2 2 1 alpha/beta hydrolase fold Isochorismatase PF00857.20 ORY04682.1 - 9.9e-14 51.9 0.0 2.2e-13 50.8 0.0 1.6 1 1 0 1 1 1 1 Isochorismatase family SQS_PSY PF00494.19 ORY04684.1 - 1.2e-37 129.9 0.0 1.5e-37 129.6 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase SabA_adhesion PF18304.1 ORY04684.1 - 0.034 13.4 0.0 0.056 12.7 0.0 1.3 1 0 0 1 1 1 0 SabA N-terminal extracellular adhesion domain IF4E PF01652.18 ORY04685.1 - 8.2e-52 175.2 0.6 1.1e-51 174.8 0.6 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Toprim_Crpt PF13342.6 ORY04685.1 - 0.13 12.3 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 C-terminal repeat of topoisomerase DnaJ-X PF14308.6 ORY04686.1 - 2.9e-77 258.9 8.3 2.9e-77 258.9 8.3 3.0 3 1 0 3 3 3 1 X-domain of DnaJ-containing DnaJ PF00226.31 ORY04686.1 - 8.6e-27 93.1 1.2 2.2e-26 91.7 1.2 1.8 1 0 0 1 1 1 1 DnaJ domain DUF908 PF06012.12 ORY04686.1 - 4.3 6.7 5.5 7.2 5.9 4.7 1.7 1 1 0 1 1 1 0 Domain of Unknown Function (DUF908) PIP5K PF01504.18 ORY04687.1 - 6.5e-38 130.5 1.6 7.2e-30 104.1 0.3 2.7 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.24 ORY04687.1 - 3.6e-29 101.7 0.0 6.6e-29 100.9 0.0 1.3 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.21 ORY04687.1 - 7.8e-15 54.8 5.8 7.8e-15 54.8 5.8 2.5 3 0 0 3 3 3 1 FYVE zinc finger Mig-14 PF07395.11 ORY04687.1 - 0.035 13.5 1.0 0.15 11.4 0.3 2.3 3 0 0 3 3 3 0 Mig-14 TPR_21 PF09976.9 ORY04687.1 - 0.12 12.1 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat-like domain C1_1 PF00130.22 ORY04687.1 - 3.9 7.4 11.2 0.057 13.3 3.5 1.9 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) TPP1 PF10341.9 ORY04688.1 - 0.00018 21.4 0.1 0.00088 19.2 0.0 2.1 2 0 0 2 2 2 1 Shelterin complex subunit, TPP1/ACD VIT1 PF01988.19 ORY04689.1 - 2.7e-72 243.1 2.6 3e-72 243.0 2.6 1.0 1 0 0 1 1 1 1 VIT family GCD14_N PF14801.6 ORY04689.1 - 0.091 12.6 1.0 0.15 11.9 1.0 1.4 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit N-term DUF2207 PF09972.9 ORY04689.1 - 0.096 11.4 0.1 0.12 11.1 0.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4131 PF13567.6 ORY04689.1 - 1.2 8.8 4.3 1.3 8.7 0.1 2.5 1 1 2 3 3 3 0 Domain of unknown function (DUF4131) DUF1989 PF09347.10 ORY04690.1 - 9.7e-34 116.4 0.0 1.6e-33 115.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) Cupin_2 PF07883.11 ORY04691.1 - 4.5e-07 29.5 0.1 7.4e-07 28.8 0.1 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 ORY04691.1 - 0.005 16.5 0.0 0.0058 16.3 0.0 1.1 1 0 0 1 1 1 1 Cupin HET PF06985.11 ORY04747.1 - 3.8e-27 95.4 0.0 5.8e-27 94.8 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ketoacyl-synt PF00109.26 ORY04748.1 - 2.8e-72 243.3 0.0 6.6e-72 242.1 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 ORY04748.1 - 2.2e-44 151.5 0.0 9.1e-44 149.5 0.0 2.2 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.21 ORY04748.1 - 4.6e-43 147.9 0.0 8.7e-43 147.0 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 ORY04748.1 - 1.5e-40 139.4 0.0 2.4e-40 138.6 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 ORY04748.1 - 1.1e-29 102.8 0.4 1.4e-13 50.9 0.0 2.7 1 1 1 2 2 2 2 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 ORY04748.1 - 2.1e-13 50.7 0.0 7.1e-13 49.0 0.0 1.9 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 ORY04748.1 - 6.4e-08 32.3 0.0 2.9e-07 30.1 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase Thiolase_N PF00108.23 ORY04748.1 - 0.0005 19.5 0.1 0.0011 18.5 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain PP-binding PF00550.25 ORY04748.1 - 0.0072 16.7 0.0 0.021 15.2 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site ACP_syn_III PF08545.10 ORY04748.1 - 0.35 10.8 2.1 0.66 9.9 0.3 2.5 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Glyco_hydro_20 PF00728.22 ORY04749.1 - 9.3e-97 324.6 0.2 1.1e-96 324.3 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 ORY04749.1 - 4.5e-24 85.7 0.0 1.2e-23 84.3 0.0 1.8 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 ORY04749.1 - 1.7e-05 25.6 0.1 5.1e-05 24.0 0.1 1.8 2 1 0 2 2 2 1 Glycosyl hydrolase family 20, domain 2 Mannosyl_trans3 PF11051.8 ORY04750.1 - 7.4e-05 22.2 0.0 0.00011 21.7 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative Glyco_transf_8 PF01501.20 ORY04750.1 - 0.1 12.1 0.8 0.32 10.5 0.0 1.9 2 0 0 2 2 2 0 Glycosyl transferase family 8 Ribosomal_L11_N PF03946.14 ORY04751.1 - 2.5e-25 88.1 0.1 4.3e-25 87.3 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 ORY04751.1 - 4.7e-15 55.9 0.3 8.1e-15 55.1 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain DUF4192 PF13830.6 ORY04754.1 - 0.021 14.9 0.4 0.031 14.3 0.4 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4192) Sin3_corepress PF08295.12 ORY04754.1 - 0.21 11.7 0.0 0.55 10.3 0.0 1.7 1 0 0 1 1 1 0 Sin3 family co-repressor p450 PF00067.22 ORY04755.1 - 1.5e-52 178.9 0.0 1.2e-41 142.9 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 YqzH PF14164.6 ORY04755.1 - 0.11 12.6 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 YqzH-like protein Glyco_hydro_1 PF00232.18 ORY04756.1 - 0.07 11.5 0.0 0.094 11.1 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 1 Myb_DNA-bind_6 PF13921.6 ORY04758.1 - 0.017 15.3 4.3 0.92 9.8 0.1 4.0 4 0 0 4 4 4 0 Myb-like DNA-binding domain GHL6 PF14871.6 ORY04758.1 - 0.035 14.2 0.1 1.2 9.3 0.1 2.3 2 0 0 2 2 2 0 Hypothetical glycosyl hydrolase 6 Elong_Iki1 PF10483.9 ORY04759.1 - 0.086 12.3 0.3 0.15 11.5 0.3 1.3 1 0 0 1 1 1 0 Elongator subunit Iki1 Myb_DNA-binding PF00249.31 ORY04759.1 - 0.26 11.5 1.6 22 5.3 0.4 2.9 2 1 0 2 2 2 0 Myb-like DNA-binding domain SGT1 PF07093.11 ORY04761.1 - 6.9e-73 246.0 16.8 1.3e-71 241.8 0.0 3.7 2 1 1 3 3 3 3 SGT1 protein HET PF06985.11 ORY04763.1 - 6.4e-28 98.0 0.0 9.3e-28 97.4 0.0 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) COesterase PF00135.28 ORY04765.1 - 2e-73 248.0 0.1 3.5e-73 247.2 0.1 1.3 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 ORY04765.1 - 1.8e-09 37.8 0.6 0.0001 22.3 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 ORY04765.1 - 0.00042 19.9 0.0 0.00067 19.2 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family WLM PF08325.10 ORY04767.1 - 7.8e-27 94.6 1.2 1.7e-26 93.5 0.1 2.1 2 1 0 2 2 2 1 WLM domain DUF45 PF01863.17 ORY04767.1 - 5.7e-08 33.0 0.4 1.6e-07 31.6 0.4 1.7 1 0 0 1 1 1 1 Protein of unknown function DUF45 DZR PF12773.7 ORY04767.1 - 0.4 10.8 6.1 1 9.4 6.1 1.8 1 0 0 1 1 1 0 Double zinc ribbon zf-RanBP PF00641.18 ORY04767.1 - 0.58 9.5 12.1 0.17 11.2 2.3 2.8 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others zf-C2H2_12 PF18658.1 ORY04767.1 - 0.65 9.6 2.9 2 8.1 0.1 2.8 3 0 0 3 3 3 0 Zinc-finger C2H2-type Zn_ribbon_17 PF17120.5 ORY04767.1 - 0.97 9.1 8.6 2.5 7.8 8.7 1.7 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_10 PF16685.5 ORY04767.1 - 2.1 8.5 5.8 2.4 8.3 3.5 2.2 2 0 0 2 2 2 0 zinc RING finger of MSL2 Trimer_CC PF08954.11 ORY04768.1 - 0.037 13.6 0.1 0.037 13.6 0.1 1.7 2 0 0 2 2 2 0 Trimerisation motif BLOC1_2 PF10046.9 ORY04768.1 - 0.051 13.9 0.3 0.076 13.3 0.3 1.3 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 NolB PF17398.2 ORY04768.1 - 0.068 13.6 0.0 0.068 13.6 0.0 1.1 1 0 0 1 1 1 0 Nodulation protein NolB Pyrid_ox_like PF16242.5 ORY04769.1 - 2.1e-22 79.3 0.0 3e-22 78.8 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase like Putative_PNPOx PF01243.20 ORY04769.1 - 3.2e-08 33.7 0.0 5.2e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Hemerythrin PF01814.23 ORY04771.1 - 7.2e-07 29.9 0.1 1.5e-06 28.8 0.1 1.6 1 1 0 1 1 1 1 Hemerythrin HHE cation binding domain peroxidase PF00141.23 ORY04773.1 - 2.1e-30 106.1 0.0 3.2e-30 105.5 0.0 1.3 1 0 0 1 1 1 1 Peroxidase Peroxidase_ext PF11895.8 ORY04773.1 - 0.0038 17.1 0.0 0.025 14.5 0.0 2.2 2 0 0 2 2 2 1 Fungal peroxidase extension region DUF3597 PF12200.8 ORY04774.1 - 1.2e-15 58.2 0.0 3.5e-15 56.7 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3597) TPR_12 PF13424.6 ORY04774.1 - 3.5e-10 40.0 0.1 9.2e-10 38.7 0.1 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_10 PF13374.6 ORY04774.1 - 2.8e-09 36.6 1.0 7.8e-07 28.8 0.1 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat zf-CCHC PF00098.23 ORY04774.1 - 0.0071 16.4 7.8 0.072 13.2 3.0 2.6 2 0 0 2 2 2 2 Zinc knuckle Rap1a PF18602.1 ORY04774.1 - 0.032 14.5 0.1 8.1 6.8 0.0 3.0 2 0 0 2 2 2 0 Rap1a immunity proteins TPR_7 PF13176.6 ORY04774.1 - 0.1 12.7 0.7 0.43 10.7 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat HET PF06985.11 ORY04775.1 - 2.3e-13 50.8 4.7 1.6e-09 38.3 0.2 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Ank_5 PF13857.6 ORY04776.1 - 0.0062 16.8 0.0 0.26 11.6 0.0 2.9 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Peptidase_M20 PF01546.28 ORY04777.1 - 1.2e-22 80.7 0.0 1.9e-22 80.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 ORY04777.1 - 1.6e-05 24.8 0.1 6.3e-05 22.8 0.1 1.9 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_S8 PF00082.22 ORY04778.1 - 4.6e-18 65.5 0.1 2.5e-17 63.1 0.1 2.0 1 1 0 1 1 1 1 Subtilase family CDKN3 PF05706.12 ORY04778.1 - 0.096 12.3 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) DUF5339 PF17274.2 ORY04779.1 - 0.12 13.3 0.0 9.2 7.2 0.0 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5339) Methyltransf_25 PF13649.6 ORY04862.1 - 2.7e-05 24.8 0.0 6.3e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ORY04862.1 - 0.002 17.7 0.0 0.028 14.0 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase small domain PrmC_N PF17827.1 ORY04862.1 - 0.0026 18.3 1.2 0.0026 18.3 1.2 2.5 2 1 0 2 2 2 1 PrmC N-terminal domain Methyltransf_31 PF13847.6 ORY04862.1 - 0.0034 17.2 0.0 0.0056 16.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain N6_Mtase PF02384.16 ORY04862.1 - 0.0086 15.4 0.0 0.016 14.5 0.0 1.3 1 1 0 1 1 1 1 N-6 DNA Methylase Methyltransf_23 PF13489.6 ORY04862.1 - 0.0092 15.8 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY04862.1 - 0.013 16.2 0.0 0.03 15.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_10 PF05971.12 ORY04862.1 - 0.045 13.1 0.0 0.15 11.4 0.0 1.9 2 0 0 2 2 2 0 RNA methyltransferase Aft1_OSA PF11785.8 ORY04862.1 - 0.1 13.0 0.3 0.27 11.7 0.3 1.6 1 0 0 1 1 1 0 Aft1 osmotic stress response (OSM) domain Ubie_methyltran PF01209.18 ORY04862.1 - 0.13 11.6 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family NmrA PF05368.13 ORY04863.1 - 8.4e-47 159.7 0.0 1.1e-46 159.4 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ORY04863.1 - 2.4e-13 50.4 0.1 4.6e-13 49.5 0.2 1.4 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 ORY04863.1 - 7.2e-07 28.9 0.1 9.9e-07 28.5 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.25 ORY04863.1 - 1.7e-05 24.4 0.9 2.5e-05 23.8 0.9 1.2 1 0 0 1 1 1 1 short chain dehydrogenase TrkA_N PF02254.18 ORY04863.1 - 0.00058 20.1 0.1 0.00083 19.6 0.1 1.3 1 0 0 1 1 1 1 TrkA-N domain adh_short_C2 PF13561.6 ORY04863.1 - 0.0016 18.0 0.6 0.0023 17.5 0.6 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY04863.1 - 0.0023 17.9 0.2 0.0035 17.3 0.2 1.2 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 ORY04863.1 - 0.0028 17.1 0.0 0.0038 16.7 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 ORY04863.1 - 0.0034 16.4 0.0 0.0047 16.0 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_2 PF03446.15 ORY04863.1 - 0.0072 16.5 0.7 0.019 15.2 0.7 1.6 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 ORY04863.1 - 0.012 16.2 0.2 0.023 15.3 0.2 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent PALP PF00291.25 ORY04863.1 - 0.015 14.7 0.3 0.026 13.9 0.3 1.4 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme DFP PF04127.15 ORY04863.1 - 0.022 14.6 0.3 0.041 13.7 0.3 1.4 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein IlvN PF07991.12 ORY04863.1 - 0.028 14.0 0.5 0.057 13.0 0.5 1.5 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain ApbA PF02558.16 ORY04863.1 - 0.063 12.9 0.5 0.15 11.7 0.4 1.6 1 1 1 2 2 2 0 Ketopantoate reductase PanE/ApbA LpxI_N PF17930.1 ORY04863.1 - 0.14 12.0 0.2 0.25 11.2 0.2 1.3 1 0 0 1 1 1 0 LpxI N-terminal domain peroxidase PF00141.23 ORY04864.1 - 2.7e-23 82.8 0.0 4.1e-23 82.3 0.0 1.2 1 0 0 1 1 1 1 Peroxidase Cu-oxidase_2 PF07731.14 ORY04865.1 - 4.9e-22 78.1 1.6 2.1e-20 72.9 1.1 2.4 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 ORY04865.1 - 2.8e-15 56.4 0.3 5.5e-14 52.2 0.1 2.5 2 0 0 2 2 2 1 Multicopper oxidase NACHT PF05729.12 ORY04867.1 - 1.5e-08 34.8 0.1 3.1e-08 33.7 0.1 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 ORY04867.1 - 2.8e-07 31.1 0.3 9.5e-07 29.3 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 ORY04867.1 - 0.00075 19.8 0.1 0.055 13.7 0.0 3.4 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 ORY04867.1 - 0.0043 17.4 0.0 0.023 15.1 0.0 2.2 2 0 0 2 2 2 1 RNA helicase SesA PF17107.5 ORY04867.1 - 0.0059 16.8 6.3 0.026 14.7 3.0 2.8 2 1 0 2 2 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases AAA_33 PF13671.6 ORY04867.1 - 0.018 15.2 0.1 0.66 10.1 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA_29 PF13555.6 ORY04867.1 - 0.029 14.1 0.0 0.09 12.5 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 ORY04867.1 - 0.042 14.4 2.0 1.2 9.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 ORY04867.1 - 0.061 13.9 0.0 0.24 12.0 0.0 2.1 1 0 0 1 1 1 0 AAA domain Ploopntkinase3 PF18751.1 ORY04867.1 - 0.079 12.9 0.0 0.22 11.4 0.0 1.7 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 cobW PF02492.19 ORY04867.1 - 0.084 12.5 0.0 0.19 11.3 0.0 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 ORY04867.1 - 0.1 12.3 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 ORY04867.1 - 0.17 12.0 0.0 0.48 10.5 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase TolA_bind_tri PF16331.5 ORY04867.1 - 0.99 9.5 6.1 10 6.3 0.5 2.9 3 0 0 3 3 2 0 TolA binding protein trimerisation AA_permease_2 PF13520.6 ORY04868.1 - 2.6e-64 217.6 38.6 4.6e-64 216.8 38.7 1.3 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ORY04868.1 - 5.7e-25 87.8 41.0 7.7e-24 84.1 41.9 2.0 1 1 0 1 1 1 1 Amino acid permease NADHdeh_related PF10125.9 ORY04868.1 - 0.0039 16.6 1.8 0.0083 15.5 1.8 1.5 1 0 0 1 1 1 1 NADH dehydrogenase I, subunit N related protein DUF202 PF02656.15 ORY04868.1 - 0.09 13.2 0.5 0.09 13.2 0.5 5.0 6 2 0 6 6 6 0 Domain of unknown function (DUF202) tRNA-synt_1 PF00133.22 ORY04869.1 - 2e-48 165.1 0.8 2.6e-21 75.5 0.1 6.0 3 1 2 5 5 5 5 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.6 ORY04869.1 - 1.4e-39 135.6 0.0 2.2e-39 134.9 0.0 1.3 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.11 ORY04869.1 - 6.6e-28 97.6 0.5 2.2e-20 72.8 0.1 4.4 3 1 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 ORY04869.1 - 1.3e-09 38.1 0.0 2.4e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA DNA_ligase_ZBD PF03119.16 ORY04869.1 - 0.022 14.8 0.0 0.055 13.5 0.0 1.6 1 0 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain tRNA-synt_1e PF01406.19 ORY04869.1 - 0.03 13.7 0.0 5.4 6.3 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain Zn-ribbon_8 PF09723.10 ORY04869.1 - 0.19 11.8 1.4 0.41 10.8 0.2 2.1 2 0 0 2 2 2 0 Zinc ribbon domain zf-ribbon_3 PF13248.6 ORY04869.1 - 3.3 7.3 4.3 11 5.6 0.2 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Suc_Fer-like PF06999.12 ORY04870.1 - 5.4e-46 156.9 0.0 7e-46 156.6 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like DUF4199 PF13858.6 ORY04871.1 - 2.6 8.4 9.4 0.76 10.2 4.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF4199) Sugar_tr PF00083.24 ORY04872.1 - 1.2e-76 258.4 13.5 1.4e-76 258.2 13.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY04872.1 - 4e-15 55.6 17.6 1.2e-10 40.9 2.3 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 ORY04872.1 - 0.0024 16.8 6.5 0.0033 16.3 5.0 1.9 2 0 0 2 2 2 1 MFS_1 like family PsbT PF01405.17 ORY04872.1 - 5.7 6.8 5.9 14 5.6 5.9 1.7 1 0 0 1 1 1 0 Photosystem II reaction centre T protein MFS_1 PF07690.16 ORY04873.1 - 1.3e-38 132.8 54.9 2.4e-37 128.7 52.9 2.9 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY04873.1 - 0.0018 17.2 34.1 0.017 14.0 6.7 3.6 2 2 2 4 4 4 3 Sugar (and other) transporter UNC-93 PF05978.16 ORY04873.1 - 0.27 10.9 16.3 0.82 9.4 1.9 3.5 2 1 1 3 3 3 0 Ion channel regulatory protein UNC-93 MFS_2 PF13347.6 ORY04873.1 - 2.2 6.7 50.6 0.051 12.1 12.7 3.9 1 1 0 2 2 2 0 MFS/sugar transport protein Trypan_PARP PF05887.11 ORY04873.1 - 5 7.1 10.9 1.2 9.1 5.3 2.4 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Aconitase PF00330.20 ORY04874.1 - 3.8e-111 372.4 0.8 6.2e-110 368.3 0.8 2.4 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 ORY04874.1 - 3.3e-27 95.4 0.0 6.2e-27 94.5 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Aminotran_5 PF00266.19 ORY04875.1 - 1.1e-26 93.7 0.0 2.2e-16 59.8 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-V Mei5 PF10376.9 ORY04875.1 - 0.24 11.2 0.1 0.52 10.1 0.1 1.5 2 0 0 2 2 2 0 Double-strand recombination repair protein CorA PF01544.18 ORY04877.1 - 6.8e-08 32.2 0.6 1.3e-07 31.2 0.6 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein FAD_binding_6 PF00970.24 ORY04879.1 - 6.7e-06 26.4 0.0 0.0023 18.2 0.0 2.9 2 1 0 2 2 2 2 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 ORY04879.1 - 9.2e-05 23.1 0.0 0.001 19.7 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Holin_SPP1 PF04688.13 ORY04880.1 - 0.083 13.1 0.3 0.11 12.6 0.3 1.2 1 0 0 1 1 1 0 SPP1 phage holin DPM2 PF07297.12 ORY04880.1 - 0.71 10.2 3.3 1.2 9.5 3.3 1.3 1 1 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) Abhydrolase_3 PF07859.13 ORY04940.1 - 1.2e-40 139.7 0.0 2.3e-31 109.3 0.1 2.5 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 ORY04940.1 - 1.4e-12 47.2 0.0 2.5e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 Steryl acetyl hydrolase COesterase PF00135.28 ORY04940.1 - 0.00093 18.2 0.1 0.0028 16.6 0.1 1.6 1 1 0 1 1 1 1 Carboxylesterase family ParA PF10609.9 ORY04941.1 - 7.1e-90 300.7 0.0 8.2e-90 300.5 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 ORY04941.1 - 2.3e-12 47.1 0.0 1.8e-11 44.2 0.0 2.0 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 ORY04941.1 - 1.8e-10 41.0 0.6 8.6e-09 35.5 0.6 2.1 1 1 0 1 1 1 1 AAA domain MipZ PF09140.11 ORY04941.1 - 3.2e-06 26.6 0.1 4.8e-06 26.1 0.1 1.4 1 1 0 1 1 1 1 ATPase MipZ AAA_26 PF13500.6 ORY04941.1 - 7.2e-05 22.7 0.1 0.0012 18.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.15 ORY04941.1 - 0.00012 21.4 0.2 0.0009 18.5 0.1 2.2 2 1 1 3 3 3 1 Anion-transporting ATPase Fer4_NifH PF00142.18 ORY04941.1 - 0.0013 18.2 0.0 0.35 10.3 0.0 2.3 2 1 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_25 PF13481.6 ORY04941.1 - 0.0016 18.1 0.0 0.0037 16.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain CBP_BcsQ PF06564.12 ORY04941.1 - 0.012 15.1 0.3 0.16 11.4 0.1 2.0 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsQ CLP1_P PF16575.5 ORY04941.1 - 0.09 12.6 0.0 0.32 10.8 0.0 1.8 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop TRAUB PF08164.12 ORY04942.1 - 8.9e-30 103.0 0.1 8.9e-30 103.0 0.1 2.6 3 0 0 3 3 3 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.6 ORY04942.1 - 1.6e-28 100.1 0.8 1.6e-28 100.1 0.8 2.6 2 0 0 2 2 2 1 Apoptosis antagonizing transcription factor HET PF06985.11 ORY04944.1 - 1.5e-05 25.4 0.1 1.7e-05 25.2 0.1 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Lactonase PF10282.9 ORY04945.1 - 8.9e-79 265.2 0.0 1.2e-78 264.8 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller COesterase PF00135.28 ORY04947.1 - 7.6e-73 246.1 0.1 1.1e-72 245.7 0.1 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 ORY04947.1 - 0.0026 17.6 1.1 0.023 14.5 1.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold CitG PF01874.16 ORY04947.1 - 0.033 13.8 0.0 0.05 13.2 0.0 1.2 1 0 0 1 1 1 0 ATP:dephospho-CoA triphosphoribosyl transferase Polysacc_synt_3 PF13440.6 ORY04949.1 - 0.019 14.2 5.6 0.55 9.4 0.1 3.1 3 0 0 3 3 3 0 Polysaccharide biosynthesis protein adh_short PF00106.25 ORY04950.1 - 6e-35 120.5 0.0 7.9e-35 120.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY04950.1 - 5.3e-25 88.3 0.0 6.7e-25 88.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY04950.1 - 0.007 16.3 0.2 0.027 14.4 0.2 1.9 1 1 0 1 1 1 1 KR domain ADH_zinc_N PF00107.26 ORY04950.1 - 0.013 15.5 0.2 0.022 14.7 0.2 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Sacchrp_dh_NADP PF03435.18 ORY04950.1 - 0.025 14.8 0.1 0.046 14.0 0.1 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 ORY04950.1 - 0.028 14.7 0.2 0.061 13.6 0.1 1.5 2 0 0 2 2 2 0 TrkA-N domain 3HCDH_N PF02737.18 ORY04950.1 - 0.19 11.6 0.1 0.32 10.9 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FMO-like PF00743.19 ORY04951.1 - 1.1e-17 63.6 0.2 8e-16 57.6 0.1 2.5 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 ORY04951.1 - 3.9e-11 43.0 0.0 1.7e-10 41.0 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ORY04951.1 - 3.1e-08 33.2 0.0 1.9e-05 24.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ORY04951.1 - 5e-05 22.7 0.2 0.0042 16.4 0.2 3.1 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ORY04951.1 - 0.00011 21.4 0.4 0.003 16.8 0.0 2.9 3 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 ORY04951.1 - 0.0019 17.8 0.3 2.4 7.7 0.0 3.1 2 1 1 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.17 ORY04951.1 - 0.0094 15.2 0.0 0.017 14.4 0.0 1.3 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.22 ORY04951.1 - 0.026 13.6 0.1 6.4 5.7 0.0 2.4 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_9 PF13454.6 ORY04951.1 - 0.092 12.7 0.0 1.1 9.3 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding MFS_1 PF07690.16 ORY04952.1 - 4.6e-25 88.3 34.9 4.6e-25 88.3 34.9 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily SIS PF01380.22 ORY04954.1 - 3.5e-09 36.6 0.3 1.5e-08 34.6 0.3 1.9 1 1 0 1 1 1 1 SIS domain SIS_2 PF13580.6 ORY04954.1 - 0.00064 19.7 0.1 0.0042 17.1 0.1 2.1 1 1 0 1 1 1 1 SIS domain Acetyltransf_1 PF00583.25 ORY04955.1 - 7.6e-07 29.4 0.0 1e-06 28.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ORY04955.1 - 0.00038 20.8 0.1 0.0012 19.2 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ORY04955.1 - 0.00057 19.8 0.0 0.001 19.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 ORY04955.1 - 0.089 12.8 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Osw5 PF17062.5 ORY04958.1 - 0.36 11.0 5.3 0.43 10.7 0.1 2.8 3 0 0 3 3 3 0 Outer spore wall 5 DUF1461 PF07314.11 ORY04958.1 - 0.44 10.4 2.8 0.24 11.3 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1461) Beta-TrCP_D PF12125.8 ORY04959.1 - 0.11 12.4 0.1 0.28 11.1 0.1 1.7 1 0 0 1 1 1 0 D domain of beta-TrCP Bac_rhamnosid6H PF17389.2 ORY04960.1 - 1e-15 57.8 1.9 3.2e-14 53.0 1.1 2.1 1 1 1 2 2 2 2 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_C PF17390.2 ORY04960.1 - 5.2e-06 26.2 0.0 1.5e-05 24.7 0.0 1.8 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain Bac_rhamnosid PF05592.11 ORY04960.1 - 0.19 11.7 0.0 0.52 10.3 0.0 1.7 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase concanavalin-like domain EH_Signature PF15611.6 ORY04962.1 - 0.012 15.1 0.0 0.015 14.7 0.0 1.1 1 0 0 1 1 1 0 EH_Signature domain DUF3755 PF12579.8 ORY04962.1 - 0.063 12.9 0.1 0.26 11.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3755) Toxin_37 PF11415.8 ORY04964.1 - 0.02 14.7 2.8 0.33 10.8 0.2 2.6 2 0 0 2 2 2 0 Antifungal peptide termicin Glyco_transf_34 PF05637.12 ORY04969.1 - 5.4e-08 32.9 3.2 2e-07 31.0 3.1 1.9 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.14 ORY04969.1 - 3.7e-05 23.4 0.1 0.00012 21.7 0.1 1.8 1 1 0 1 1 1 1 Protein of unknown function, DUF273 Nucleotid_trans PF03407.16 ORY04969.1 - 0.00065 19.7 0.1 0.0011 18.9 0.1 1.5 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Sugar_tr PF00083.24 ORY04970.1 - 7.5e-93 311.8 26.8 8.8e-93 311.6 26.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY04970.1 - 9.6e-31 107.0 25.8 9.6e-31 107.0 25.8 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Chloroplast_duf PF14476.6 ORY04970.1 - 0.016 14.2 0.2 0.026 13.5 0.2 1.2 1 0 0 1 1 1 0 Petal formation-expressed Mannosidase_ig PF17786.1 ORY04971.1 - 5.3e-13 49.4 0.0 1.6e-12 47.9 0.0 1.9 1 0 0 1 1 1 1 Mannosidase Ig/CBM-like domain Ig_mannosidase PF17753.1 ORY04971.1 - 1.1e-06 28.3 0.0 2.8e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 Ig-fold domain Glyco_hydro_2 PF00703.21 ORY04971.1 - 5.1e-05 23.9 0.0 0.00041 21.0 0.0 2.5 2 1 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_2_C PF02836.17 ORY04971.1 - 0.014 14.5 0.0 0.028 13.5 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain DUF3433 PF11915.8 ORY04972.1 - 4.1e-22 78.4 0.7 7e-15 55.3 0.5 2.8 2 1 0 2 2 2 2 Protein of unknown function (DUF3433) F-box PF00646.33 ORY04973.1 - 4.3e-07 29.7 0.0 1.4e-06 28.0 0.0 1.9 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 ORY04973.1 - 0.00065 19.5 0.1 0.0016 18.2 0.1 1.7 1 0 0 1 1 1 1 F-box-like Elongin_A PF06881.11 ORY04973.1 - 0.1 13.2 0.2 0.18 12.4 0.2 1.4 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A K_oxygenase PF13434.6 ORY04973.1 - 0.13 11.3 0.1 0.2 10.8 0.1 1.1 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) TIMELESS_C PF05029.13 ORY04975.1 - 2.9 6.9 10.7 8.5 5.4 10.6 1.7 1 1 0 1 1 1 0 Timeless protein C terminal region p450 PF00067.22 ORY04976.1 - 1.1e-61 209.1 0.0 1.4e-61 208.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Dehydratase_hem PF13816.6 ORY04977.1 - 3.7e-109 364.9 0.1 4.2e-109 364.7 0.1 1.0 1 0 0 1 1 1 1 Haem-containing dehydratase DUF4188 PF13826.6 ORY04977.1 - 1.3e-05 25.5 3.1 0.0016 18.8 0.1 2.7 3 1 0 3 3 3 2 Domain of unknown function (DUF4188) AA_permease_2 PF13520.6 ORY05046.1 - 1.2e-47 162.8 47.3 1.4e-47 162.5 47.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ORY05046.1 - 1.3e-24 86.6 38.2 1.8e-24 86.2 38.2 1.1 1 0 0 1 1 1 1 Amino acid permease DUF3792 PF12670.7 ORY05046.1 - 0.054 13.7 0.2 0.054 13.7 0.2 5.7 5 2 1 6 6 6 0 Protein of unknown function (DUF3792) CbtB PF09489.10 ORY05046.1 - 2.5 8.3 4.4 7.6 6.7 0.3 3.8 2 0 0 2 2 2 0 Probable cobalt transporter subunit (CbtB) YlaH PF14036.6 ORY05046.1 - 7.3 7.0 10.1 0.56 10.6 1.9 3.1 3 0 0 3 3 3 0 YlaH-like protein SLAC1 PF03595.17 ORY05049.1 - 3.3e-81 273.1 43.9 3.8e-81 272.9 43.9 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Transp_cyt_pur PF02133.15 ORY05052.1 - 3.3e-91 306.3 33.9 3.8e-91 306.1 33.9 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF917 PF06032.12 ORY05053.1 - 3.8e-126 420.7 0.9 3.8e-126 420.7 0.9 2.0 3 0 0 3 3 3 1 Protein of unknown function (DUF917) Hydantoinase_A PF01968.18 ORY05053.1 - 5.3e-31 107.9 2.6 1.7e-26 93.2 0.2 3.4 3 0 0 3 3 3 2 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 ORY05053.1 - 1.2e-29 103.3 4.8 2.4e-28 99.0 0.1 2.7 3 0 0 3 3 3 2 Hydantoinase/oxoprolinase N-terminal region BcrAD_BadFG PF01869.20 ORY05053.1 - 0.001 18.6 0.3 0.001 18.6 0.3 2.9 3 1 0 3 3 3 1 BadF/BadG/BcrA/BcrD ATPase family ROK PF00480.20 ORY05053.1 - 0.003 17.1 0.0 0.0078 15.7 0.0 1.7 1 0 0 1 1 1 1 ROK family MutL PF13941.6 ORY05053.1 - 0.0042 15.7 4.2 0.014 14.1 0.0 2.5 3 0 0 3 3 3 1 MutL protein StbA PF06406.11 ORY05053.1 - 0.013 14.8 0.0 3.2 6.9 0.0 2.6 2 1 0 2 2 2 0 StbA protein Mito_carr PF00153.27 ORY05054.1 - 2.4e-55 184.5 3.5 7.2e-20 70.7 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein P5CR_dimer PF14748.6 ORY05054.1 - 0.038 14.3 1.1 0.23 11.7 0.1 2.3 2 0 0 2 2 2 0 Pyrroline-5-carboxylate reductase dimerisation DUF3042 PF11240.8 ORY05054.1 - 0.071 13.1 0.3 14 5.8 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3042) ADH_N PF08240.12 ORY05055.1 - 7.8e-21 74.0 1.5 1.6e-20 73.0 1.5 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORY05055.1 - 1.6e-11 44.3 0.0 3.2e-09 36.8 0.0 2.9 2 1 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 ORY05055.1 - 2.4e-06 27.1 0.0 3.6e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 ORY05055.1 - 5.2e-05 22.6 0.1 7.2e-05 22.2 0.1 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_2 PF03446.15 ORY05055.1 - 0.026 14.7 0.0 0.039 14.1 0.0 1.2 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase GFO_IDH_MocA PF01408.22 ORY05055.1 - 0.033 15.0 0.0 0.061 14.2 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold 3HCDH_N PF02737.18 ORY05055.1 - 0.13 12.2 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Peptidase_S8 PF00082.22 ORY05056.1 - 1.3e-36 126.4 17.5 2.2e-36 125.7 17.5 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 ORY05056.1 - 0.0004 21.0 0.1 0.00094 19.8 0.1 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 Runt PF00853.19 ORY05056.1 - 0.14 11.7 0.1 0.28 10.7 0.1 1.5 1 0 0 1 1 1 0 Runt domain Sortilin-Vps10 PF15902.5 ORY05058.1 - 3.4e-285 945.7 13.6 4.6e-151 503.6 6.6 2.1 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 ORY05058.1 - 2.3e-91 304.7 17.1 1.2e-45 155.9 8.2 2.5 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, C-terminal PSII_BNR PF14870.6 ORY05058.1 - 3.8e-08 33.0 5.8 0.00027 20.3 0.0 4.8 5 1 0 5 5 5 2 Photosynthesis system II assembly factor YCF48 BNR PF02012.20 ORY05058.1 - 5.1e-06 25.7 33.2 0.56 10.4 0.4 10.1 9 0 0 9 9 9 3 BNR/Asp-box repeat F5_F8_type_C PF00754.25 ORY05058.1 - 0.96 9.6 17.4 0.28 11.3 0.5 6.8 5 3 2 8 8 8 0 F5/8 type C domain BNR_6 PF15899.5 ORY05058.1 - 9.4 6.6 15.5 1.1 9.5 0.3 5.6 6 0 0 6 6 6 0 BNR-Asp box repeat WD40 PF00400.32 ORY05059.1 - 3.7e-07 30.7 8.9 0.79 10.7 0.6 6.1 7 1 0 7 7 7 3 WD domain, G-beta repeat Dynein_IC2 PF11540.8 ORY05059.1 - 0.051 13.5 0.1 0.11 12.5 0.1 1.6 1 0 0 1 1 1 0 Cytoplasmic dynein 1 intermediate chain 2 ATP-synt_E PF05680.12 ORY05060.1 - 3.1e-22 78.7 0.0 3.5e-22 78.5 0.0 1.0 1 0 0 1 1 1 1 ATP synthase E chain Dynamin_M PF01031.20 ORY05061.1 - 5.9e-109 363.7 0.0 1.3e-108 362.6 0.0 1.5 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 ORY05061.1 - 7.5e-57 192.0 0.1 2.2e-56 190.5 0.0 1.9 2 0 0 2 2 2 1 Dynamin family GED PF02212.18 ORY05061.1 - 1.2e-31 108.7 2.2 1.2e-31 108.7 2.2 1.9 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 ORY05061.1 - 0.0001 22.4 0.3 0.0017 18.4 0.3 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase PBP PF01161.20 ORY05062.1 - 1.3e-20 74.0 0.1 2.1e-20 73.4 0.1 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Isochorismatase PF00857.20 ORY05062.1 - 2.3e-14 54.0 0.0 8.6e-14 52.1 0.0 1.8 1 1 0 1 1 1 1 Isochorismatase family Cas_Cas1 PF01867.16 ORY05062.1 - 0.18 10.9 0.0 0.26 10.4 0.0 1.1 1 0 0 1 1 1 0 CRISPR associated protein Cas1 DUF4240 PF14024.6 ORY05063.1 - 0.057 13.6 0.0 0.073 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4240) p450 PF00067.22 ORY05064.1 - 3.6e-59 200.7 0.0 4.9e-59 200.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Abhydrolase_1 PF00561.20 ORY05066.1 - 8.3e-25 87.9 0.0 2.1e-24 86.5 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORY05066.1 - 5.6e-12 46.7 0.0 6.9e-12 46.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORY05066.1 - 2.2e-09 36.9 0.0 1e-08 34.7 0.0 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DUF1057 PF06342.12 ORY05066.1 - 1.6e-05 24.1 0.1 4.8e-05 22.5 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF1057) GNAT_acetyltr_2 PF13718.6 ORY05067.1 - 3.7e-99 330.7 0.0 6.7e-99 329.9 0.0 1.4 1 0 0 1 1 1 1 GNAT acetyltransferase 2 tRNA_bind_2 PF13725.6 ORY05067.1 - 5e-92 307.9 0.1 8.9e-92 307.0 0.1 1.4 1 0 0 1 1 1 1 Possible tRNA binding domain Helicase_RecD PF05127.14 ORY05067.1 - 1.5e-65 220.3 0.0 4.9e-65 218.7 0.0 1.9 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.11 ORY05067.1 - 2.5e-34 117.1 0.3 5.8e-34 115.9 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1726) AAA_30 PF13604.6 ORY05067.1 - 0.00026 20.8 0.9 0.0094 15.7 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 ORY05067.1 - 0.013 15.8 0.0 0.56 10.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 ORY05067.1 - 0.091 13.1 0.2 0.47 10.8 0.0 2.3 3 0 0 3 3 3 0 AAA domain Acetyltransf_1 PF00583.25 ORY05067.1 - 0.1 12.9 0.0 0.38 11.0 0.0 2.0 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family GHMP_kinases_N PF00288.26 ORY05067.1 - 0.15 12.3 0.1 0.44 10.8 0.1 1.8 1 0 0 1 1 1 0 GHMP kinases N terminal domain HemY_N PF07219.13 ORY05068.1 - 0.13 12.4 0.4 0.22 11.7 0.4 1.3 1 0 0 1 1 1 0 HemY protein N-terminus FMN_dh PF01070.18 ORY05070.1 - 3.3e-48 164.5 0.8 8.5e-30 103.9 0.0 2.0 1 1 1 2 2 2 2 FMN-dependent dehydrogenase Glu_synthase PF01645.17 ORY05070.1 - 0.0028 16.8 0.1 0.0044 16.2 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 ORY05070.1 - 0.034 13.2 0.1 0.056 12.4 0.1 1.3 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain ABC_tran PF00005.27 ORY05071.1 - 0.0016 18.9 0.0 0.0041 17.6 0.0 1.7 1 0 0 1 1 1 1 ABC transporter Patatin PF01734.22 ORY05071.1 - 0.0059 16.8 0.0 0.014 15.6 0.0 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase AAA_23 PF13476.6 ORY05071.1 - 0.0065 17.0 0.8 0.015 15.8 0.1 1.9 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.6 ORY05071.1 - 0.018 14.7 0.5 0.047 13.4 0.3 1.7 1 1 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 ORY05071.1 - 0.02 14.8 0.1 0.039 13.8 0.1 1.3 1 0 0 1 1 1 0 RsgA GTPase Zeta_toxin PF06414.12 ORY05071.1 - 0.057 12.7 0.1 0.12 11.6 0.1 1.5 1 0 0 1 1 1 0 Zeta toxin C1_2 PF03107.16 ORY05071.1 - 0.46 10.8 7.2 1.5 9.2 7.2 1.9 1 0 0 1 1 1 0 C1 domain zf-B_box PF00643.24 ORY05071.1 - 0.71 10.1 13.0 0.27 11.4 7.3 2.7 2 0 0 2 2 2 0 B-box zinc finger DUF87 PF01935.17 ORY05071.1 - 0.73 9.9 1.9 0.95 9.5 0.4 1.9 2 0 0 2 2 2 0 Helicase HerA, central domain zf-C3HC4_2 PF13923.6 ORY05071.1 - 1.6 8.6 19.6 0.99 9.3 5.4 3.2 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 ORY05071.1 - 2.4 8.1 21.4 0.49 10.3 7.1 2.8 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 ORY05071.1 - 7.1 6.6 19.9 0.24 11.3 6.9 2.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORY05071.1 - 9.2 6.4 17.7 0.098 12.7 6.0 2.9 2 0 0 2 2 2 0 RING-type zinc-finger zf-C3HC4 PF00097.25 ORY05071.1 - 9.9 6.1 18.3 0.062 13.2 6.2 2.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Abhydrolase_3 PF07859.13 ORY05072.1 - 1.2e-09 38.3 0.0 2.9e-09 37.1 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 ORY05072.1 - 2.1e-06 27.4 0.0 0.0031 17.0 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family DLH PF01738.18 ORY05072.1 - 0.00021 20.9 0.0 0.1 12.1 0.0 2.1 2 0 0 2 2 2 2 Dienelactone hydrolase family Hydrolase_4 PF12146.8 ORY05072.1 - 0.0032 16.8 0.0 0.042 13.1 0.0 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 ORY05072.1 - 0.017 14.0 0.0 0.022 13.7 0.0 1.1 1 0 0 1 1 1 0 Chlorophyllase enzyme Esterase PF00756.20 ORY05072.1 - 0.12 12.0 0.0 0.15 11.6 0.0 1.4 1 1 0 1 1 1 0 Putative esterase Abhydrolase_2 PF02230.16 ORY05072.1 - 0.17 11.6 0.0 18 5.0 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase DUF3669 PF12417.8 ORY05073.1 - 1.5e-17 63.6 0.1 3.7e-17 62.3 0.1 1.7 1 0 0 1 1 1 1 Zinc finger protein DUF1937 PF09152.10 ORY05073.1 - 0.041 14.7 0.0 0.082 13.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1937) PTR2 PF00854.21 ORY05075.1 - 2.9e-93 312.8 3.8 9.6e-93 311.1 3.8 1.7 1 1 0 1 1 1 1 POT family OST3_OST6 PF04756.13 ORY05075.1 - 0.26 10.6 1.7 4 6.7 0.2 2.3 2 0 0 2 2 2 0 OST3 / OST6 family, transporter family Cation_efflux PF01545.21 ORY05077.1 - 2.2e-55 187.5 0.7 4.5e-55 186.5 0.7 1.5 1 1 0 1 1 1 1 Cation efflux family NicO PF03824.16 ORY05077.1 - 0.0056 16.1 0.7 0.014 14.8 0.7 1.7 1 0 0 1 1 1 1 High-affinity nickel-transport protein Eno-Rase_NADH_b PF12242.8 ORY05077.1 - 0.11 12.3 0.0 0.28 10.9 0.0 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Dicty_CAR PF05462.11 ORY05077.1 - 1.5 7.9 4.5 0.18 10.9 0.3 1.5 2 0 0 2 2 2 0 Slime mold cyclic AMP receptor DUF202 PF02656.15 ORY05078.1 - 5.3e-17 62.0 4.3 5.3e-17 62.0 4.3 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) PsbH PF00737.20 ORY05078.1 - 0.09 12.5 0.8 0.09 12.5 0.8 2.1 2 0 0 2 2 2 0 Photosystem II 10 kDa phosphoprotein Phage_holin_2_4 PF16082.5 ORY05078.1 - 1.3 8.8 3.7 7.9 6.3 0.5 2.6 2 1 1 3 3 3 0 Bacteriophage holin family, superfamily II-like IPTL-CTERM PF18203.1 ORY05078.1 - 2.7 8.0 6.6 0.81 9.7 1.6 2.4 2 0 0 2 2 2 0 IPTL-CTERM motif DUF4131 PF13567.6 ORY05078.1 - 3.5 7.3 8.7 2 8.0 4.9 1.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4131) F-box PF00646.33 ORY05079.1 - 0.00013 21.7 0.0 0.00035 20.4 0.0 1.7 1 0 0 1 1 1 1 F-box domain Acetyltransf_1 PF00583.25 ORY05081.1 - 2.2e-09 37.6 0.1 5.5e-09 36.3 0.1 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ORY05081.1 - 3.5e-09 36.7 0.0 3.8e-05 23.6 0.0 2.1 1 1 1 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ORY05081.1 - 3.5e-06 27.4 0.0 5.4e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF1720 PF08226.11 ORY05083.1 - 0.31 11.5 9.1 67 4.0 3.7 5.0 2 1 0 3 3 3 0 Domain of unknown function (DUF1720) Mucin-like PF16058.5 ORY05083.1 - 9.9 6.3 82.8 0.095 12.8 16.6 4.9 1 1 4 5 5 5 0 Mucin-like KicB PF03882.14 ORY05143.1 - 0.052 13.8 0.3 0.14 12.4 0.3 1.7 1 0 0 1 1 1 0 MukF winged-helix domain Hid1 PF12722.7 ORY05143.1 - 2.8 6.0 8.0 4.2 5.4 8.0 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Presenilin PF01080.17 ORY05143.1 - 6.1 5.5 5.8 9.3 4.9 5.8 1.3 1 0 0 1 1 1 0 Presenilin CAF1 PF04857.20 ORY05144.1 - 1.1e-78 264.6 0.1 1.1e-78 264.6 0.1 1.6 2 0 0 2 2 2 1 CAF1 family ribonuclease HSDR_N PF04313.14 ORY05144.1 - 0.017 15.1 0.0 0.12 12.3 0.0 2.2 2 0 0 2 2 2 0 Type I restriction enzyme R protein N terminus (HSDR_N) DNA_pol_A_exo1 PF01612.20 ORY05144.1 - 0.026 14.3 0.0 0.07 12.8 0.0 1.8 1 0 0 1 1 1 0 3'-5' exonuclease Prominin PF05478.11 ORY05144.1 - 0.12 10.3 0.0 0.18 9.7 0.0 1.1 1 0 0 1 1 1 0 Prominin CRIM PF16978.5 ORY05146.1 - 5.1e-42 143.3 0.0 1e-41 142.4 0.0 1.5 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), middle CRIM domain SIN1_PH PF16979.5 ORY05146.1 - 1.4e-30 105.8 0.6 2.6e-30 104.9 0.6 1.5 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology PH PF00169.29 ORY05146.1 - 0.017 15.6 0.0 0.037 14.5 0.0 1.6 1 0 0 1 1 1 0 PH domain PRCC PF10253.9 ORY05147.1 - 2.1e-31 110.4 6.7 2.1e-31 110.4 6.7 3.7 2 1 1 3 3 3 1 Mitotic checkpoint regulator, MAD2B-interacting SET PF00856.28 ORY05148.1 - 4e-10 40.3 0.1 8e-10 39.4 0.1 1.4 1 0 0 1 1 1 1 SET domain GFA PF04828.14 ORY05149.1 - 2.5e-20 72.6 0.2 3.4e-20 72.2 0.2 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Transpos_assoc PF13963.6 ORY05149.1 - 0.057 13.7 0.2 0.53 10.6 0.1 2.2 2 0 0 2 2 2 0 Transposase-associated domain DUF2040 PF09745.9 ORY05150.1 - 6.1e-38 129.6 22.9 6.1e-38 129.6 22.9 4.0 3 2 1 4 4 4 3 Coiled-coil domain-containing protein 55 (DUF2040) Glyco_hydro_11 PF00457.17 ORY05152.1 - 1.4e-77 259.3 19.5 1.6e-77 259.1 19.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 DUF3810 PF12725.7 ORY05153.1 - 0.0085 15.5 0.4 0.047 13.0 0.4 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF3810) DUF3144 PF11342.8 ORY05153.1 - 0.057 13.7 1.0 0.11 12.8 1.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3144) DJ-1_PfpI PF01965.24 ORY05154.1 - 6.1e-15 55.4 0.0 7.5e-15 55.1 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family ADH_zinc_N_2 PF13602.6 ORY05155.1 - 2.2e-15 57.9 0.0 5.7e-15 56.5 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 ORY05155.1 - 2.3e-11 43.8 0.0 4.3e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ORY05155.1 - 4.2e-06 26.6 0.5 0.00089 19.1 0.1 2.4 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain NACHT PF05729.12 ORY05157.1 - 4.7e-11 42.9 0.1 1.5e-10 41.3 0.0 1.9 2 0 0 2 2 2 1 NACHT domain SesA PF17107.5 ORY05157.1 - 2.4e-06 27.7 0.2 6.4e-06 26.4 0.2 1.7 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases AAA_16 PF13191.6 ORY05157.1 - 0.00015 22.2 0.2 0.0015 18.9 0.0 2.6 2 1 1 3 3 3 1 AAA ATPase domain ATPase_2 PF01637.18 ORY05157.1 - 0.0035 17.3 0.0 0.01 15.8 0.0 1.7 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 ORY05157.1 - 0.004 17.4 0.0 0.038 14.3 0.0 2.5 3 0 0 3 3 3 1 AAA domain Viral_helicase1 PF01443.18 ORY05157.1 - 0.005 16.6 0.0 0.0096 15.7 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.22 ORY05157.1 - 0.019 14.1 4.7 0.081 12.1 0.1 2.8 2 1 0 2 2 2 0 NB-ARC domain cobW PF02492.19 ORY05157.1 - 0.023 14.3 0.1 0.062 12.9 0.1 1.7 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.27 ORY05157.1 - 0.041 14.4 0.2 0.13 12.8 0.2 1.8 1 0 0 1 1 1 0 ABC transporter AAA_30 PF13604.6 ORY05157.1 - 0.046 13.4 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 ORY05157.1 - 0.11 12.7 0.1 0.52 10.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 ORY05157.1 - 0.16 11.8 0.2 0.39 10.5 0.2 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Hemerythrin PF01814.23 ORY05157.1 - 0.4 11.3 2.9 10 6.7 0.1 3.6 3 1 0 3 3 3 0 Hemerythrin HHE cation binding domain AAA_23 PF13476.6 ORY05157.1 - 0.43 11.1 2.6 5.6 7.4 0.1 2.3 2 0 0 2 2 2 0 AAA domain FAD_binding_3 PF01494.19 ORY05158.1 - 4.1e-14 52.6 0.0 6e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 ORY05158.1 - 1.7e-08 34.5 4.4 0.00095 18.8 1.4 2.7 1 1 2 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ORY05158.1 - 2.6e-08 33.4 1.1 1.2e-07 31.2 1.1 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORY05158.1 - 3.1e-08 33.7 0.1 7.4e-08 32.5 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 ORY05158.1 - 1.5e-05 24.5 1.1 0.014 14.7 0.1 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 ORY05158.1 - 6.7e-05 22.1 2.1 7.5e-05 22.0 0.9 1.6 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.22 ORY05158.1 - 0.0002 20.6 1.0 0.00098 18.3 0.4 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.14 ORY05158.1 - 0.00025 19.9 2.3 0.00031 19.6 0.6 1.8 2 0 0 2 2 2 1 HI0933-like protein AlaDh_PNT_C PF01262.21 ORY05158.1 - 0.0034 16.7 0.5 0.0034 16.7 0.5 1.7 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 ORY05158.1 - 0.0045 16.3 1.7 0.02 14.2 1.2 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 ORY05158.1 - 0.005 15.7 1.4 0.059 12.2 0.2 2.5 3 0 0 3 3 3 1 Tryptophan halogenase FAD_oxidored PF12831.7 ORY05158.1 - 0.0083 15.5 0.2 0.013 14.9 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 ORY05158.1 - 0.058 14.0 0.5 0.058 14.0 0.5 2.6 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase Rossmann-like PF10727.9 ORY05158.1 - 0.071 13.0 0.3 0.16 11.9 0.3 1.6 1 0 0 1 1 1 0 Rossmann-like domain CDI PF02234.19 ORY05158.1 - 0.079 13.2 0.7 0.35 11.1 0.7 2.2 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor Thi4 PF01946.17 ORY05158.1 - 0.085 12.1 1.0 0.1 11.8 0.1 1.5 2 0 0 2 2 2 0 Thi4 family ApbA PF02558.16 ORY05158.1 - 0.093 12.4 0.2 0.17 11.6 0.2 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_2 PF03446.15 ORY05158.1 - 0.14 12.3 0.1 0.64 10.2 0.1 2.0 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 ORY05158.1 - 0.16 11.8 0.6 0.34 10.8 0.2 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.6 ORY05158.1 - 0.23 11.4 2.0 2.7 7.9 0.2 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 ORY05158.1 - 0.29 10.1 1.8 0.73 8.8 1.8 1.6 1 1 0 1 1 1 0 Lycopene cyclase protein Nse4_C PF08743.10 ORY05159.1 - 1.5e-33 114.9 0.7 4.6e-33 113.3 0.0 2.2 2 0 0 2 2 2 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.6 ORY05159.1 - 3.9e-08 33.3 1.4 3.9e-08 33.3 1.4 2.7 2 1 0 2 2 2 1 Binding domain of Nse4/EID3 to Nse3-MAGE PI3Ka PF00613.20 ORY05160.1 - 2e-56 190.3 0.0 3.2e-56 189.7 0.0 1.2 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 ORY05160.1 - 4.2e-45 154.5 0.0 2.6e-30 106.1 0.0 2.6 2 1 1 3 3 3 2 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.24 ORY05160.1 - 1.8e-31 108.9 0.0 2.9e-31 108.2 0.0 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 VGLL4 PF15245.6 ORY05160.1 - 1.6 8.8 3.2 0.82 9.7 0.3 2.0 2 0 0 2 2 2 0 Transcription cofactor vestigial-like protein 4 DUF2439 PF10382.9 ORY05161.1 - 1.4e-27 95.8 1.4 9e-27 93.2 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2439) SH3_9 PF14604.6 ORY05162.1 - 1.8e-13 50.1 0.0 3.3e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 ORY05162.1 - 8.9e-13 47.6 0.0 1.6e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 SH3 domain BAR PF03114.18 ORY05162.1 - 1.6e-12 47.6 4.7 2.3e-12 47.1 4.7 1.1 1 0 0 1 1 1 1 BAR domain SH3_2 PF07653.17 ORY05162.1 - 1.6e-09 37.3 0.0 3.3e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain CorA PF01544.18 ORY05162.1 - 0.99 8.7 3.6 17 4.6 1.6 2.1 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Fig1 PF12351.8 ORY05163.1 - 0.8 9.6 5.1 1.2 9.0 4.3 1.6 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 LapA_dom PF06305.11 ORY05163.1 - 3.4 7.5 5.0 1.3 8.9 0.0 2.6 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain COPI_assoc PF08507.10 ORY05163.1 - 9.6 6.3 16.0 0.78 9.8 4.8 2.3 1 1 1 2 2 2 0 COPI associated protein LapA_dom PF06305.11 ORY05165.1 - 0.032 14.0 1.4 7.6 6.4 0.0 2.6 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain UPF0060 PF02694.15 ORY05165.1 - 0.15 12.3 4.0 0.3 11.3 4.0 1.5 1 0 0 1 1 1 0 Uncharacterised BCR, YnfA/UPF0060 family p450 PF00067.22 ORY05166.1 - 1.6e-35 122.8 0.0 3.9e-34 118.2 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 HALZ PF02183.18 ORY05167.1 - 0.019 15.2 0.2 0.029 14.6 0.2 1.3 1 0 0 1 1 1 0 Homeobox associated leucine zipper DivIC PF04977.15 ORY05167.1 - 0.02 14.7 1.1 0.029 14.1 1.1 1.2 1 0 0 1 1 1 0 Septum formation initiator CENP-H PF05837.12 ORY05167.1 - 0.12 12.8 0.7 0.16 12.4 0.7 1.2 1 0 0 1 1 1 0 Centromere protein H (CENP-H) Spc7 PF08317.11 ORY05167.1 - 0.2 10.5 1.2 0.24 10.2 1.2 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein NUDIX PF00293.28 ORY05168.1 - 2.3e-15 56.8 0.0 3.8e-15 56.1 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain SE PF08491.10 ORY05171.1 - 3.9e-97 324.6 0.0 4.9e-97 324.3 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.19 ORY05171.1 - 6e-07 29.0 1.2 3.4e-05 23.3 0.4 2.2 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 ORY05171.1 - 1.8e-06 27.8 0.4 1.9e-05 24.5 0.5 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 ORY05171.1 - 2.7e-06 27.0 0.9 4.2e-06 26.4 0.9 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 ORY05171.1 - 0.00016 20.9 0.4 0.00028 20.1 0.4 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.17 ORY05171.1 - 0.00031 20.1 0.2 0.0028 16.9 0.0 2.0 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 ORY05171.1 - 0.00043 19.5 1.9 0.00064 18.9 1.9 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 ORY05171.1 - 0.00099 18.4 0.0 0.0018 17.6 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORY05171.1 - 0.003 18.1 0.5 0.0062 17.1 0.5 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 ORY05171.1 - 0.0045 16.3 0.3 0.0082 15.5 0.3 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_8 PF13450.6 ORY05171.1 - 0.0069 16.6 0.8 0.015 15.5 0.8 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 ORY05171.1 - 0.0087 14.8 1.8 0.025 13.3 1.3 1.8 1 1 1 2 2 2 1 HI0933-like protein Trp_halogenase PF04820.14 ORY05171.1 - 0.019 13.9 0.5 0.24 10.2 0.4 2.3 3 0 0 3 3 3 0 Tryptophan halogenase ApbA PF02558.16 ORY05171.1 - 0.047 13.3 0.2 0.098 12.3 0.2 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 ORY05171.1 - 0.073 13.0 0.3 0.13 12.1 0.3 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 ORY05171.1 - 0.11 11.5 0.4 0.27 10.2 0.4 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein ThiF PF00899.21 ORY05171.1 - 0.12 11.7 0.2 0.26 10.6 0.0 1.5 2 0 0 2 2 2 0 ThiF family Shikimate_DH PF01488.20 ORY05171.1 - 0.14 12.3 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_N PF03721.14 ORY05171.1 - 0.32 10.6 1.3 0.77 9.3 0.2 1.9 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain CTP_synth_N PF06418.14 ORY05172.1 - 2.1e-125 417.4 0.8 2.9e-125 416.9 0.8 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 ORY05172.1 - 7.8e-57 192.1 0.0 1.2e-56 191.5 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 ORY05172.1 - 4.8e-06 26.5 0.3 3.8e-05 23.6 0.2 2.4 2 1 0 2 2 2 1 Peptidase C26 CbiA PF01656.23 ORY05172.1 - 0.085 12.9 0.0 0.24 11.4 0.0 1.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Velvet PF11754.8 ORY05173.1 - 3.6e-59 200.7 0.0 8.6e-37 127.4 0.0 3.7 2 2 1 3 3 3 2 Velvet factor Bin3 PF06859.12 ORY05175.1 - 1.3e-23 83.7 0.1 1.8e-23 83.2 0.1 1.2 1 0 0 1 1 1 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_23 PF13489.6 ORY05175.1 - 2.9e-10 40.2 0.0 4.1e-10 39.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY05175.1 - 2.2e-08 34.1 0.0 1.2e-06 28.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY05175.1 - 2.6e-07 31.3 0.0 1.3e-06 29.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY05175.1 - 3.5e-07 30.8 0.0 0.00011 22.8 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY05175.1 - 5.1e-06 27.0 0.0 0.0021 18.6 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_PK PF05891.12 ORY05175.1 - 0.0028 17.2 0.0 0.011 15.2 0.0 1.8 2 0 0 2 2 2 1 AdoMet dependent proline di-methyltransferase MTS PF05175.14 ORY05175.1 - 0.005 16.4 0.0 0.013 15.0 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_18 PF12847.7 ORY05175.1 - 0.012 15.6 0.0 0.016 15.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.17 ORY05175.1 - 0.07 12.6 0.0 0.18 11.2 0.0 1.6 2 0 0 2 2 2 0 Putative methyltransferase PrmA PF06325.13 ORY05175.1 - 0.1 12.0 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DUF1349 PF07081.11 ORY05176.1 - 9.5e-25 87.3 0.0 2.7e-23 82.6 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1349) CorA PF01544.18 ORY05178.1 - 1.8e-07 30.8 3.2 2.5e-07 30.3 3.2 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF2231 PF09990.9 ORY05178.1 - 0.0039 17.6 0.4 0.0057 17.1 0.4 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2231) IZUMO PF15005.6 ORY05179.1 - 0.21 12.1 0.2 0.37 11.3 0.2 1.3 1 0 0 1 1 1 0 Izumo sperm-egg fusion, Ig domain-associated adh_short PF00106.25 ORY05180.1 - 1e-32 113.2 0.0 1.4e-32 112.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY05180.1 - 2.4e-22 79.6 0.0 3.4e-22 79.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 ORY05180.1 - 1.4e-05 25.0 0.1 5.5e-05 23.1 0.1 1.9 2 0 0 2 2 2 1 NAD(P)H-binding KR PF08659.10 ORY05180.1 - 0.00011 22.2 0.0 0.00014 21.8 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 ORY05180.1 - 0.0053 16.2 0.0 0.0076 15.6 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 ORY05180.1 - 0.035 13.6 0.0 0.046 13.2 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NmrA PF05368.13 ORY05180.1 - 0.096 12.2 0.1 0.17 11.4 0.1 1.4 1 0 0 1 1 1 0 NmrA-like family ADH_zinc_N PF00107.26 ORY05180.1 - 0.11 12.5 0.2 0.32 11.0 0.1 1.8 2 1 0 2 2 2 0 Zinc-binding dehydrogenase Pkinase PF00069.25 ORY05181.1 - 5.3e-07 29.3 0.0 7.8e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY05181.1 - 0.0009 18.6 0.0 0.0011 18.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase DUF202 PF02656.15 ORY05182.1 - 1.2 9.6 7.6 8.6 6.9 1.7 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF202) LRR_4 PF12799.7 ORY05185.1 - 7.1e-33 112.1 20.1 1.2e-09 38.3 0.8 6.2 5 1 0 6 6 6 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY05185.1 - 5.3e-19 67.7 60.4 2.6e-07 30.3 6.3 5.7 2 1 6 8 8 8 8 Leucine rich repeat LRR_9 PF14580.6 ORY05185.1 - 4.8e-11 42.5 19.1 3.6e-06 26.6 3.7 3.6 1 1 3 5 5 5 3 Leucine-rich repeat LRR_1 PF00560.33 ORY05185.1 - 0.00044 20.4 19.4 1.4 9.7 0.0 8.0 8 1 0 8 8 8 2 Leucine Rich Repeat LRR_6 PF13516.6 ORY05185.1 - 0.058 13.5 23.5 2.8 8.2 0.0 7.6 9 0 0 9 9 9 0 Leucine Rich repeat Abhydrolase_1 PF00561.20 ORY05187.1 - 2e-49 168.5 0.0 3.9e-49 167.6 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 ORY05187.1 - 0.0022 16.9 0.0 0.0033 16.3 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_6 PF12697.7 ORY05187.1 - 0.0035 18.0 4.4 0.011 16.3 4.4 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORY05187.1 - 0.043 13.1 0.0 1 8.6 0.0 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Npun_R1517 PF18068.1 ORY05188.1 - 0.03 14.7 0.0 0.089 13.1 0.0 1.7 2 0 0 2 2 2 0 Npun R1517 ketoacyl-synt PF00109.26 ORY05189.1 - 5.6e-53 180.1 0.7 2e-51 175.0 0.0 2.0 2 0 0 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 ORY05189.1 - 9e-33 112.8 0.3 5.7e-32 110.2 0.2 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_C PF02803.18 ORY05189.1 - 2.2e-06 27.3 1.0 0.0004 20.0 0.1 3.2 3 0 0 3 3 3 2 Thiolase, C-terminal domain Thiolase_N PF00108.23 ORY05189.1 - 2.9e-06 26.8 0.4 0.00013 21.5 0.1 2.1 2 0 0 2 2 2 2 Thiolase, N-terminal domain NicO PF03824.16 ORY05190.1 - 3.4e-66 223.5 10.4 3.4e-66 223.5 10.4 1.5 2 0 0 2 2 2 1 High-affinity nickel-transport protein stn_TNFRSF12A PF12191.8 ORY05190.1 - 0.25 11.6 2.7 0.82 9.9 0.5 2.5 2 0 0 2 2 2 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Gemini_mov PF01708.16 ORY05190.1 - 0.58 9.9 6.4 4.5 7.1 0.1 3.4 3 0 0 3 3 3 0 Geminivirus putative movement protein DHHC PF01529.20 ORY05190.1 - 3.2 7.9 11.2 26 4.9 0.3 3.3 2 1 0 2 2 2 0 DHHC palmitoyltransferase MARVEL PF01284.23 ORY05264.1 - 1.5e-05 25.0 13.8 2.6e-05 24.3 13.8 1.3 1 0 0 1 1 1 1 Membrane-associating domain TFIIA PF03153.13 ORY05264.1 - 1 9.3 20.4 1.3 9.0 20.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF1195 PF06708.11 ORY05264.1 - 3.1 7.6 4.7 3 7.6 1.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1195) RSN1_7TM PF02714.15 ORY05265.1 - 0.096 12.0 0.1 0.096 12.0 0.1 1.6 2 0 0 2 2 2 0 Calcium-dependent channel, 7TM region, putative phosphate Shisa PF13908.6 ORY05266.1 - 0.015 15.6 0.2 0.43 10.8 0.1 2.2 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator DUF2070 PF09843.9 ORY05266.1 - 0.028 12.7 1.1 0.033 12.5 1.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF5134 PF17197.4 ORY05266.1 - 0.95 9.3 7.2 6.5 6.6 0.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF5134) Cyt-b5 PF00173.28 ORY05267.1 - 7.5e-15 54.8 0.0 1.2e-14 54.2 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAPRTase PF04095.16 ORY05268.1 - 7.4e-55 186.2 1.2 1.8e-53 181.6 1.2 2.1 1 1 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family NAPRTase_N PF17767.1 ORY05268.1 - 2.9e-31 108.4 0.1 4.6e-31 107.8 0.1 1.3 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain Syntaxin PF00804.25 ORY05269.1 - 1.1e-18 67.6 7.0 6.6e-18 65.1 7.0 2.0 1 1 0 1 1 1 1 Syntaxin SNARE PF05739.19 ORY05269.1 - 2.5e-08 33.8 6.7 1.4e-07 31.4 6.7 2.4 1 1 0 1 1 1 1 SNARE domain Use1 PF09753.9 ORY05269.1 - 2e-06 27.7 1.0 2.9e-06 27.2 1.0 1.2 1 0 0 1 1 1 1 Membrane fusion protein Use1 Syntaxin_2 PF14523.6 ORY05269.1 - 4.9e-05 23.6 1.7 0.0046 17.3 0.0 2.4 2 0 0 2 2 2 1 Syntaxin-like protein RPW8 PF05659.11 ORY05269.1 - 0.00029 20.5 0.9 0.011 15.4 0.4 2.2 2 0 0 2 2 2 1 Arabidopsis broad-spectrum mildew resistance protein RPW8 Baculo_PEP_C PF04513.12 ORY05269.1 - 0.013 15.5 2.2 3.3 7.8 0.5 3.0 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus BLOC1_2 PF10046.9 ORY05269.1 - 0.021 15.1 3.5 0.27 11.6 0.9 2.9 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Tweety PF04906.13 ORY05269.1 - 0.024 13.3 2.9 0.084 11.5 2.6 1.9 2 0 0 2 2 2 0 Tweety DUF4094 PF13334.6 ORY05269.1 - 0.034 14.6 0.2 0.39 11.2 0.4 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4094) Pox_EPC_I2-L1 PF12575.8 ORY05269.1 - 0.04 14.1 0.3 0.075 13.3 0.3 1.5 1 0 0 1 1 1 0 Poxvirus entry protein complex L1 and I2 DUF2207 PF09972.9 ORY05269.1 - 0.042 12.6 0.0 0.054 12.3 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) UPF0184 PF03670.13 ORY05269.1 - 0.044 14.2 0.4 0.17 12.3 0.0 2.1 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0184) Baculo_F PF12259.8 ORY05269.1 - 0.047 12.2 8.5 0.58 8.6 0.0 2.5 2 1 0 2 2 2 0 Baculovirus F protein Spectrin PF00435.21 ORY05269.1 - 0.064 13.7 4.5 4.2 7.9 0.7 3.2 3 1 1 4 4 4 0 Spectrin repeat 7tm_7 PF08395.12 ORY05269.1 - 0.067 12.4 2.0 1.5 7.9 0.1 2.3 2 0 0 2 2 2 0 7tm Chemosensory receptor ETRAMP PF09716.10 ORY05269.1 - 0.074 13.1 0.0 0.18 11.9 0.0 1.6 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) MCU PF04678.13 ORY05269.1 - 0.11 12.6 4.3 0.52 10.4 3.6 2.2 1 1 0 1 1 1 0 Mitochondrial calcium uniporter NPV_P10 PF05531.12 ORY05269.1 - 0.13 12.8 5.1 9.1 6.8 1.2 3.0 2 2 0 2 2 2 0 Nucleopolyhedrovirus P10 protein PBP1_TM PF14812.6 ORY05269.1 - 0.16 12.4 0.1 0.16 12.4 0.1 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal BatA PF07584.11 ORY05269.1 - 0.18 12.2 1.3 0.38 11.1 0.1 2.0 2 0 0 2 2 2 0 Aerotolerance regulator N-terminal DUF1664 PF07889.12 ORY05269.1 - 0.24 11.5 4.8 8.6 6.4 1.7 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) FTA4 PF13093.6 ORY05269.1 - 0.38 10.6 7.4 14 5.5 7.4 2.3 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DHR10 PF18595.1 ORY05269.1 - 0.77 9.8 9.9 0.38 10.8 2.2 3.0 3 0 0 3 3 3 0 Designed helical repeat protein 10 domain DUF4407 PF14362.6 ORY05269.1 - 2.2 7.5 9.6 1e+02 2.1 9.6 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Spc29 PF17082.5 ORY05269.1 - 3.5 7.4 9.7 43 3.8 9.7 2.2 1 1 0 1 1 1 0 Spindle Pole Component 29 zf-CpG_bind_C PF12269.8 ORY05269.1 - 4.2 7.1 7.1 8.1 6.2 1.8 2.5 2 1 1 3 3 3 0 CpG binding protein zinc finger C terminal domain V-SNARE PF05008.15 ORY05269.1 - 4.9 7.6 10.1 3.5 8.1 2.6 3.4 3 1 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus DUF2203 PF09969.9 ORY05269.1 - 5.7 7.7 7.5 6.4 7.5 1.8 2.7 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) PHY PF00360.20 ORY05270.1 - 2.4e-22 79.2 0.0 4.7e-22 78.2 0.0 1.4 1 0 0 1 1 1 1 Phytochrome region Response_reg PF00072.24 ORY05270.1 - 9.7e-15 54.7 0.0 1.1e-11 44.9 0.1 2.5 2 0 0 2 2 2 2 Response regulator receiver domain GAF PF01590.26 ORY05270.1 - 1.3e-13 51.7 0.0 4e-13 50.2 0.0 1.8 1 0 0 1 1 1 1 GAF domain HATPase_c PF02518.26 ORY05270.1 - 3.4e-13 50.1 0.1 9.1e-13 48.7 0.1 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 ORY05270.1 - 9.4e-09 35.2 0.3 2.5e-08 33.8 0.3 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_2 PF08446.11 ORY05270.1 - 0.00012 22.8 0.0 0.0012 19.5 0.0 2.6 2 0 0 2 2 2 1 PAS fold HATPase_c_3 PF13589.6 ORY05270.1 - 0.015 15.1 0.0 0.029 14.2 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GAPES3 PF17154.4 ORY05270.1 - 0.035 14.1 0.1 0.085 12.8 0.1 1.6 1 0 0 1 1 1 0 Gammaproteobacterial periplasmic sensor domain Abhydrolase_6 PF12697.7 ORY05271.1 - 2e-12 48.2 2.7 2.2e-12 48.0 2.7 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family UL40 PF10682.9 ORY05271.1 - 0.059 13.1 0.0 0.089 12.5 0.0 1.2 1 0 0 1 1 1 0 Glycoprotein of human cytomegalovirus HHV-5 MFS_1 PF07690.16 ORY05272.1 - 1.7e-38 132.5 24.1 1.7e-38 132.5 24.1 2.4 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY05272.1 - 2.4e-13 49.8 3.6 2.4e-13 49.8 3.6 3.1 3 0 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.13 ORY05272.1 - 0.0043 15.5 6.3 0.0083 14.6 6.3 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MAP17 PF15807.5 ORY05272.1 - 0.043 14.1 0.1 1.3 9.3 0.0 2.5 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 DUF4592 PF15262.6 ORY05272.1 - 0.87 10.3 5.6 2.2 8.9 5.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4592) KAR9 PF08580.10 ORY05272.1 - 1.1 7.8 3.9 1.6 7.1 0.3 2.0 2 0 0 2 2 2 0 Yeast cortical protein KAR9 NUSAP PF16006.5 ORY05273.1 - 0.15 11.8 2.7 0.19 11.5 2.7 1.1 1 0 0 1 1 1 0 Nucleolar and spindle-associated protein APC_u9 PF16633.5 ORY05274.1 - 0.12 13.4 0.2 0.23 12.6 0.2 1.6 1 0 0 1 1 1 0 Unstructured region on APC between 1st two creatine-rich regions Dcc1 PF09724.9 ORY05277.1 - 0.22 10.8 3.4 0.35 10.1 3.4 1.2 1 0 0 1 1 1 0 Sister chromatid cohesion protein Dcc1 Asp-B-Hydro_N PF05279.11 ORY05277.1 - 9.1 6.3 19.8 1.1 9.3 11.8 2.2 2 0 0 2 2 2 0 Aspartyl beta-hydroxylase N-terminal region PARP PF00644.20 ORY05278.1 - 6.8e-08 32.3 0.1 1.7e-07 31.0 0.1 1.6 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain LRR_4 PF12799.7 ORY05279.1 - 4.9e-13 49.0 8.0 0.00053 20.3 1.5 4.2 4 0 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY05279.1 - 4.9e-11 42.2 14.2 1e-07 31.6 4.5 3.7 3 1 1 4 4 4 3 Leucine rich repeat LRR_6 PF13516.6 ORY05279.1 - 0.00042 20.2 14.1 2.8 8.2 0.1 5.7 4 1 1 5 5 5 2 Leucine Rich repeat LRR_9 PF14580.6 ORY05279.1 - 0.01 15.3 3.2 0.073 12.6 1.3 2.2 1 1 1 2 2 2 0 Leucine-rich repeat LRR_1 PF00560.33 ORY05279.1 - 0.039 14.5 12.2 29 5.7 0.4 6.2 6 0 0 6 6 6 0 Leucine Rich Repeat Metallophos PF00149.28 ORY05280.1 - 3.9e-40 138.5 0.1 5.1e-40 138.2 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 ORY05280.1 - 5.6e-23 81.1 1.8 8.4e-23 80.6 1.1 1.7 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain TMEM132D_C PF15706.5 ORY05283.1 - 0.058 13.2 0.0 0.097 12.5 0.0 1.4 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term DUF575 PF04746.12 ORY05283.1 - 0.17 12.1 0.0 0.31 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF575) HIP1_clath_bdg PF16515.5 ORY05284.1 - 0.85 10.3 4.4 5.3 7.7 4.4 2.5 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 ATP-synt_DE_N PF02823.16 ORY05285.1 - 5.2e-17 61.5 0.1 7.4e-17 61.0 0.1 1.3 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain DLH PF01738.18 ORY05288.1 - 5.3e-11 42.5 0.1 7.3e-11 42.0 0.1 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family zf-primase PF09329.11 ORY05289.1 - 2.7 7.9 5.9 1.1 9.2 0.2 2.5 2 0 0 2 2 2 0 Primase zinc finger Zn_clus PF00172.18 ORY05291.1 - 4.6e-14 52.3 31.5 2.5e-08 33.9 12.5 2.3 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Alk_phosphatase PF00245.20 ORY05292.1 - 4.3e-77 259.8 0.7 6.1e-76 256.0 0.7 2.0 1 1 0 1 1 1 1 Alkaline phosphatase Phosphodiest PF01663.22 ORY05292.1 - 4.4e-07 29.8 0.9 6.5e-07 29.3 0.2 1.6 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 ORY05292.1 - 5.1e-07 29.4 0.1 1.1e-05 25.0 0.1 2.3 1 1 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.18 ORY05292.1 - 0.029 13.7 0.1 0.062 12.6 0.1 1.5 1 0 0 1 1 1 0 Metalloenzyme superfamily DUF229 PF02995.17 ORY05292.1 - 0.091 11.3 0.2 0.14 10.8 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) COX15-CtaA PF02628.15 ORY05292.1 - 0.16 11.1 0.0 0.25 10.3 0.0 1.2 1 0 0 1 1 1 0 Cytochrome oxidase assembly protein tRNA-synt_2 PF00152.20 ORY05295.1 - 1.1e-92 310.4 0.0 1.4e-92 310.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.20 ORY05295.1 - 0.00094 18.7 0.0 0.0027 17.3 0.0 1.7 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.25 ORY05295.1 - 0.017 15.1 0.0 0.043 13.8 0.0 1.7 2 0 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) CS PF04969.16 ORY05296.1 - 7.5e-17 62.1 0.0 1.6e-16 61.1 0.0 1.6 1 0 0 1 1 1 1 CS domain Phage_Gp19 PF09355.10 ORY05296.1 - 0.065 13.7 0.1 0.13 12.7 0.1 1.5 1 0 0 1 1 1 0 Phage protein Gp19/Gp15/Gp42 PGBA_C PF15437.6 ORY05296.1 - 0.21 12.0 4.1 9.5 6.7 0.7 2.3 2 0 0 2 2 2 0 Plasminogen-binding protein pgbA C-terminal ANTH PF07651.16 ORY05297.1 - 5.9e-60 202.6 0.0 8.7e-60 202.0 0.0 1.3 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.20 ORY05297.1 - 0.00011 22.3 0.0 0.00025 21.1 0.0 1.7 1 1 0 1 1 1 1 ENTH domain AMP-binding PF00501.28 ORY05298.1 - 1.2e-63 215.2 0.0 3e-63 213.9 0.0 1.6 2 0 0 2 2 2 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORY05298.1 - 3.5e-09 37.5 0.0 6.1e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DGF-1_C PF11040.8 ORY05298.1 - 0.071 13.1 0.2 6.2 6.9 0.0 2.6 2 0 0 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus XPG_N PF00752.17 ORY05300.1 - 7.4e-36 122.7 0.1 2.3e-35 121.1 0.0 2.0 2 0 0 2 2 2 1 XPG N-terminal domain HET PF06985.11 ORY05300.1 - 2.3e-27 96.2 0.7 7.9e-27 94.4 0.0 2.4 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) XPG_I PF00867.18 ORY05300.1 - 2e-24 85.8 0.0 5.3e-24 84.4 0.0 1.8 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.20 ORY05300.1 - 0.0003 21.3 0.0 0.0011 19.6 0.0 1.9 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold Transposase_20 PF02371.16 ORY05300.1 - 0.0033 17.7 0.0 0.01 16.1 0.0 1.8 1 0 0 1 1 1 1 Transposase IS116/IS110/IS902 family HHH_5 PF14520.6 ORY05300.1 - 0.0073 16.9 0.0 0.02 15.5 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain UIM PF02809.20 ORY05300.1 - 0.59 10.2 16.3 0.012 15.5 5.3 3.5 2 0 0 2 2 2 0 Ubiquitin interaction motif preSET_CXC PF18264.1 ORY05301.1 - 0.00011 22.5 14.1 0.00011 22.5 14.1 3.8 1 1 2 3 3 3 1 CXC domain Spc7_N PF15402.6 ORY05302.1 - 4.3e-81 273.5 36.0 1.3e-68 232.2 30.4 3.3 1 1 1 2 2 2 2 N-terminus of kinetochore NMS complex subunit Spc7 PDE6_gamma PF04868.12 ORY05302.1 - 0.0017 18.6 3.2 0.005 17.1 0.5 2.4 2 0 0 2 2 2 1 Retinal cGMP phosphodiesterase, gamma subunit Flu_M2 PF00599.17 ORY05371.1 - 0.053 13.6 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 Influenza Matrix protein (M2) MAGE PF01454.19 ORY05372.1 - 0.18 11.5 0.0 0.18 11.5 0.0 1.0 1 0 0 1 1 1 0 MAGE family Cation_efflux PF01545.21 ORY05373.1 - 0.017 14.9 1.9 0.022 14.5 1.7 1.3 1 1 0 1 1 1 0 Cation efflux family zf-MYND PF01753.18 ORY05374.1 - 5e-13 48.9 12.6 8.2e-13 48.2 12.6 1.4 1 0 0 1 1 1 1 MYND finger Ecl1 PF12855.7 ORY05374.1 - 0.013 16.6 18.2 0.013 16.6 18.2 1.6 2 0 0 2 2 2 0 ECL1/2/3 zinc binding proteins zf-C6H2 PF15801.5 ORY05374.1 - 0.016 15.5 9.6 0.026 14.8 7.7 2.0 1 1 1 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding Ribosomal_L33 PF00471.20 ORY05378.1 - 5e-05 23.7 0.0 0.00012 22.5 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L33 FlaC_arch PF05377.11 ORY05382.1 - 1.5 9.3 16.2 3.4 8.1 0.2 5.5 4 2 0 4 4 4 0 Flagella accessory protein C (FlaC) AAA_13 PF13166.6 ORY05382.1 - 2.8 6.5 38.2 0.18 10.4 16.2 2.3 1 1 1 2 2 2 0 AAA domain LPG_synthase_TM PF03706.13 ORY05383.1 - 0.019 14.5 0.2 0.031 13.8 0.2 1.3 1 0 0 1 1 1 0 Lysylphosphatidylglycerol synthase TM region CD99L2 PF12301.8 ORY05383.1 - 0.027 14.8 0.2 0.051 13.9 0.2 1.5 1 0 0 1 1 1 0 CD99 antigen like protein 2 zf-Nse PF11789.8 ORY05384.1 - 6.5e-22 77.1 0.1 1.3e-21 76.1 0.1 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 ORY05384.1 - 0.0031 17.5 0.0 0.0066 16.5 0.0 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-MIZ PF02891.20 ORY05384.1 - 0.015 15.1 0.1 0.031 14.0 0.1 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-C3HC4_2 PF13923.6 ORY05384.1 - 0.017 15.0 0.2 0.042 13.7 0.0 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) MYT1 PF08474.11 ORY05384.1 - 1.2 9.0 7.8 0.15 12.0 0.4 2.4 2 1 0 2 2 2 0 Myelin transcription factor 1 ALMT PF11744.8 ORY05384.1 - 6 5.6 8.5 10 4.8 8.5 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter Methyltransf_7 PF03492.15 ORY05385.1 - 4.2e-29 101.8 0.0 1.5e-28 100.0 0.0 1.7 1 1 0 1 1 1 1 SAM dependent carboxyl methyltransferase DUF58 PF01882.18 ORY05385.1 - 0.049 13.9 0.0 0.15 12.4 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function DUF58 Mito_carr PF00153.27 ORY05386.1 - 2.3e-53 178.1 4.4 2.7e-18 65.7 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 ORY05386.1 - 0.015 14.4 1.8 0.055 12.6 1.3 2.2 1 1 0 1 1 1 0 Gammaproteobacterial serine protease ketoacyl-synt PF00109.26 ORY05388.1 - 3e-63 213.8 0.1 6.2e-63 212.7 0.1 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain SAT PF16073.5 ORY05388.1 - 9.8e-47 159.7 0.0 7.3e-46 156.8 0.0 2.4 2 1 1 3 3 3 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Acyl_transf_1 PF00698.21 ORY05388.1 - 2.9e-42 145.3 0.2 4.8e-42 144.6 0.2 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 ORY05388.1 - 7.5e-31 106.6 0.4 2.6e-30 104.9 0.4 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.20 ORY05388.1 - 1.8e-19 70.8 0.0 6.8e-19 68.9 0.0 2.0 1 0 0 1 1 1 1 Thioesterase domain PP-binding PF00550.25 ORY05388.1 - 2.7e-11 43.6 0.3 8.6e-11 42.0 0.1 2.0 2 0 0 2 2 2 1 Phosphopantetheine attachment site KAsynt_C_assoc PF16197.5 ORY05388.1 - 1.6e-05 25.3 0.0 5.1e-05 23.7 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension LIDHydrolase PF10230.9 ORY05388.1 - 0.16 11.5 0.1 6 6.3 0.0 2.4 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase TPR_12 PF13424.6 ORY05389.1 - 3e-07 30.6 2.5 8.9e-07 29.1 1.6 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 ORY05389.1 - 6.9e-06 25.8 1.5 0.01 15.7 0.2 3.3 2 0 0 2 2 2 2 Tetratricopeptide repeat NB-ARC PF00931.22 ORY05389.1 - 0.0034 16.6 0.0 0.0051 16.0 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain Git3 PF11710.8 ORY05391.1 - 3.9e-16 59.4 13.9 4e-16 59.4 11.6 2.0 2 1 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.21 ORY05391.1 - 0.0003 20.2 1.4 0.00037 19.9 1.4 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Dicty_CAR PF05462.11 ORY05391.1 - 0.0024 17.1 4.6 0.0045 16.2 4.6 1.4 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor GPR_Gpa2_C PF11970.8 ORY05391.1 - 0.0041 17.1 5.6 0.012 15.7 0.1 2.9 2 1 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term Lipase_GDSL_2 PF13472.6 ORY05392.1 - 1.1e-13 52.0 0.0 1.6e-13 51.4 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 ORY05392.1 - 7.5e-08 32.6 0.0 2.9e-06 27.4 0.0 2.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 ORY05392.1 - 0.063 13.4 0.0 0.097 12.8 0.0 1.3 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family tRNA-synt_2c PF01411.19 ORY05392.1 - 0.17 10.3 0.0 0.22 10.0 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class II (A) Oxidored_FMN PF00724.20 ORY05393.1 - 1.8e-75 254.4 0.0 2.4e-75 254.0 0.0 1.2 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF1848 PF08902.11 ORY05393.1 - 0.0023 17.7 0.0 0.0033 17.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1848) DUF3481 PF11980.8 ORY05394.1 - 0.065 12.9 0.3 0.075 12.8 0.3 1.2 1 0 0 1 1 1 0 C-terminal domain of neuropilin glycoprotein DUF1996 PF09362.10 ORY05395.1 - 3.2e-83 279.3 2.8 4.3e-83 278.9 2.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) APH PF01636.23 ORY05470.1 - 1.4e-10 41.5 0.0 2.1e-10 40.9 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 ORY05470.1 - 0.00019 21.1 0.0 0.00024 20.8 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 ORY05470.1 - 0.075 12.6 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Pkinase PF00069.25 ORY05470.1 - 0.17 11.3 0.0 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain Amino_oxidase PF01593.24 ORY05471.1 - 6.1e-22 78.5 0.0 8.7e-20 71.4 0.0 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 ORY05471.1 - 9e-15 54.7 0.2 2.1e-14 53.5 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ORY05471.1 - 1.3e-09 38.1 0.0 1.6e-08 34.6 0.0 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ORY05471.1 - 1.9e-07 30.6 0.0 3e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ORY05471.1 - 6.9e-06 25.4 2.4 1.2e-05 24.5 2.4 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 ORY05471.1 - 6.9e-05 22.4 2.1 0.0001 21.8 2.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 ORY05471.1 - 0.00021 20.6 0.4 0.00033 20.0 0.4 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 ORY05471.1 - 0.001 17.8 0.1 0.0069 15.1 0.8 1.8 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.6 ORY05471.1 - 0.0028 16.9 0.8 0.0049 16.2 0.8 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ORY05471.1 - 0.0032 17.4 0.1 0.023 14.7 0.2 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding GDI PF00996.18 ORY05471.1 - 0.0035 15.9 0.1 0.13 10.8 0.0 2.1 2 0 0 2 2 2 1 GDP dissociation inhibitor Thi4 PF01946.17 ORY05471.1 - 0.0044 16.3 0.4 0.0078 15.5 0.4 1.3 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.22 ORY05471.1 - 0.011 14.8 1.5 0.018 14.1 1.5 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox PF00070.27 ORY05471.1 - 0.013 16.1 2.2 0.034 14.7 1.5 2.1 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 ORY05471.1 - 0.046 12.8 0.6 0.091 11.8 0.4 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein UDPG_MGDP_dh_N PF03721.14 ORY05471.1 - 0.053 13.1 0.4 0.1 12.2 0.4 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_7 PF13241.6 ORY05471.1 - 0.056 13.9 0.0 0.1 13.1 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding ApbA PF02558.16 ORY05471.1 - 0.068 12.8 0.1 0.12 12.0 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Trp_halogenase PF04820.14 ORY05471.1 - 0.072 11.9 0.9 0.12 11.2 0.9 1.3 1 0 0 1 1 1 0 Tryptophan halogenase 3HCDH_N PF02737.18 ORY05471.1 - 0.098 12.5 1.3 0.18 11.7 1.3 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 ORY05471.1 - 0.18 11.1 2.0 0.3 10.4 2.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain IlvN PF07991.12 ORY05471.1 - 0.21 11.2 0.2 0.55 9.8 0.1 1.7 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 ORY05471.1 - 0.23 11.7 0.1 0.38 11.0 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain SQS_PSY PF00494.19 ORY05472.1 - 9.5e-65 218.7 0.4 1.2e-64 218.4 0.4 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase RPE65 PF03055.15 ORY05473.1 - 7.4e-118 394.7 0.0 8.5e-118 394.5 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein NUC205 PF08168.11 ORY05473.1 - 0.036 13.6 0.0 0.094 12.2 0.0 1.8 1 0 0 1 1 1 0 NUC205 domain PPI_Ypi1 PF07491.11 ORY05473.1 - 0.2 11.5 0.0 0.45 10.4 0.0 1.5 1 0 0 1 1 1 0 Protein phosphatase inhibitor Bac_rhodopsin PF01036.18 ORY05474.1 - 1.3e-58 198.2 10.3 1.6e-58 197.9 10.3 1.1 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein MtN3_slv PF03083.16 ORY05474.1 - 0.17 11.9 3.9 8.7 6.5 0.1 3.5 4 0 0 4 4 4 0 Sugar efflux transporter for intercellular exchange LptF_LptG PF03739.14 ORY05474.1 - 0.33 9.8 5.7 0.1 11.5 0.9 2.1 2 0 0 2 2 2 0 Lipopolysaccharide export system permease LptF/LptG MerC PF03203.14 ORY05474.1 - 0.59 10.6 10.5 1.4 9.4 0.6 2.3 1 1 1 2 2 2 0 MerC mercury resistance protein DUF3810 PF12725.7 ORY05474.1 - 0.81 9.0 4.1 9.1 5.5 1.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) Wzy_C PF04932.15 ORY05474.1 - 3.3 7.3 6.6 0.31 10.7 0.8 2.0 2 0 0 2 2 2 0 O-Antigen ligase DUF4131 PF13567.6 ORY05474.1 - 3.6 7.2 8.0 4.2 7.0 1.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) HET PF06985.11 ORY05475.1 - 1.6e-29 103.1 0.0 2.2e-29 102.7 0.0 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Glyco_transf_24 PF18404.1 ORY05475.1 - 0.0085 15.5 0.0 0.013 15.0 0.0 1.2 1 0 0 1 1 1 1 Glucosyltransferase 24 Annexin PF00191.20 ORY05476.1 - 7.4e-25 86.8 2.3 6.6e-06 26.1 0.0 4.3 4 0 0 4 4 4 4 Annexin HET PF06985.11 ORY05477.1 - 4.3e-31 108.2 2.2 9.9e-31 107.1 1.0 2.3 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Transposase_20 PF02371.16 ORY05477.1 - 0.09 13.1 1.4 0.21 11.9 1.4 1.6 1 0 0 1 1 1 0 Transposase IS116/IS110/IS902 family F-box-like PF12937.7 ORY05478.1 - 0.00043 20.1 0.6 0.0011 18.8 0.6 1.7 1 0 0 1 1 1 1 F-box-like GPI2 PF06432.11 ORY05479.1 - 9.4e-123 409.1 1.7 1.1e-122 408.9 1.7 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase FAST_1 PF06743.15 ORY05480.1 - 0.12 12.3 0.1 0.21 11.6 0.1 1.3 1 0 0 1 1 1 0 FAST kinase-like protein, subdomain 1 DUF1996 PF09362.10 ORY05482.1 - 2e-65 221.1 5.2 2.4e-65 220.8 5.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) CPP1-like PF11833.8 ORY05484.1 - 0.27 10.9 2.3 0.21 11.2 1.0 1.5 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like DUF3638 PF12340.8 ORY05485.1 - 2.9e-90 301.5 0.0 6.5e-90 300.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.8 ORY05485.1 - 2.7e-19 68.2 0.3 6.1e-19 67.1 0.3 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) ING PF12998.7 ORY05485.1 - 0.047 14.3 2.4 1.1 9.8 0.2 2.9 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding AAA_16 PF13191.6 ORY05487.1 - 4.3e-11 43.5 0.1 2.7e-09 37.6 0.0 3.6 3 0 0 3 3 3 1 AAA ATPase domain Goodbye PF17109.5 ORY05487.1 - 2.6e-09 37.5 1.0 1.9e-08 34.8 0.0 2.8 2 0 0 2 2 2 1 fungal STAND N-terminal Goodbye domain NACHT PF05729.12 ORY05487.1 - 1.2e-07 31.9 0.0 8.6e-07 29.0 0.0 2.5 1 1 0 1 1 1 1 NACHT domain TPR_12 PF13424.6 ORY05487.1 - 2.2e-05 24.7 4.2 1.9 8.8 0.2 4.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 ORY05487.1 - 0.00038 20.3 6.6 0.26 11.5 0.4 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat AAA_22 PF13401.6 ORY05487.1 - 0.0011 19.2 0.0 0.025 14.9 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 ORY05487.1 - 0.015 15.3 0.0 0.064 13.3 0.0 2.1 1 1 0 1 1 1 0 AAA domain ZZ PF00569.17 ORY05487.1 - 0.032 14.0 4.2 0.064 13.1 4.2 1.4 1 0 0 1 1 1 0 Zinc finger, ZZ type TPR_1 PF00515.28 ORY05487.1 - 0.036 13.9 5.0 1.3 9.0 0.6 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 ORY05487.1 - 0.057 14.3 8.3 4.6 8.3 0.1 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat RNA_helicase PF00910.22 ORY05487.1 - 0.078 13.4 0.0 0.24 11.8 0.0 1.9 1 0 0 1 1 1 0 RNA helicase C_LFY_FLO PF17538.2 ORY05487.1 - 0.15 11.6 0.0 0.4 10.1 0.0 1.7 1 0 0 1 1 1 0 DNA Binding Domain (C-terminal) Leafy/Floricaula Torsin PF06309.11 ORY05487.1 - 0.17 12.0 0.0 0.41 10.7 0.0 1.6 1 0 0 1 1 1 0 Torsin TPR_8 PF13181.6 ORY05487.1 - 0.18 12.1 10.0 21 5.7 0.1 5.4 6 0 0 6 6 5 0 Tetratricopeptide repeat p450 PF00067.22 ORY05488.1 - 1.2e-61 208.9 0.0 1.5e-61 208.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Cu-oxidase_3 PF07732.15 ORY05490.1 - 7.4e-40 135.7 0.8 6.6e-39 132.6 0.2 2.4 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 ORY05490.1 - 6.1e-32 110.2 8.3 7.6e-30 103.4 0.5 3.3 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 ORY05490.1 - 1.7e-26 93.2 0.0 4.7e-25 88.6 0.0 2.3 2 0 0 2 2 2 1 Multicopper oxidase CobT PF06213.12 ORY05491.1 - 2 7.7 15.5 2.3 7.5 15.5 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Nop14 PF04147.12 ORY05491.1 - 2 6.5 18.2 2.5 6.2 18.2 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 ORY05491.1 - 4.2 6.7 19.0 4.6 6.6 19.0 1.1 1 0 0 1 1 1 0 SDA1 SURF2 PF05477.11 ORY05491.1 - 4.5 6.9 10.8 5 6.7 10.8 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) BUD22 PF09073.10 ORY05491.1 - 7.5 5.8 21.5 7.9 5.7 21.5 1.0 1 0 0 1 1 1 0 BUD22 HET PF06985.11 ORY05492.1 - 6.3e-21 75.3 0.5 8.7e-21 74.8 0.5 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HTH_Tnp_Tc3_2 PF01498.18 ORY05493.1 - 4.1e-12 46.2 2.9 4.2e-11 42.9 1.3 2.4 2 0 0 2 2 2 1 Transposase HTH_38 PF13936.6 ORY05493.1 - 5.4e-07 29.3 0.2 1.4e-06 27.9 0.2 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 ORY05493.1 - 0.0011 18.9 0.1 0.53 10.3 0.0 2.4 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_23 PF13384.6 ORY05493.1 - 0.0014 18.4 1.7 0.024 14.4 0.1 2.5 2 0 0 2 2 2 1 Homeodomain-like domain CENP-B_N PF04218.13 ORY05493.1 - 0.0038 16.8 0.1 0.011 15.3 0.1 1.8 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_10 PF04967.12 ORY05493.1 - 0.023 14.5 0.0 1.3 8.9 0.0 2.7 2 0 0 2 2 2 0 HTH DNA binding domain Cro PF09048.10 ORY05493.1 - 0.027 14.5 0.0 0.7 10.0 0.0 2.4 2 0 0 2 2 2 0 Cro HTH_3 PF01381.22 ORY05493.1 - 0.048 13.7 0.0 0.16 12.0 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix GerE PF00196.19 ORY05493.1 - 0.061 12.9 0.5 1.3 8.6 0.0 2.6 3 0 0 3 3 3 0 Bacterial regulatory proteins, luxR family DUF2738 PF10927.8 ORY05493.1 - 0.07 12.2 0.0 0.15 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2738) Sigma70_r4_2 PF08281.12 ORY05493.1 - 0.081 12.6 0.0 0.26 11.0 0.0 1.8 2 0 0 2 2 2 0 Sigma-70, region 4 zf-C2HE PF16278.5 ORY05493.1 - 0.12 12.8 0.6 4.5 7.8 0.1 2.5 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger HTH_29 PF13551.6 ORY05493.1 - 0.12 12.4 0.4 1 9.4 0.1 2.2 2 0 0 2 2 2 0 Winged helix-turn helix HTH_37 PF13744.6 ORY05493.1 - 0.14 12.1 0.0 0.82 9.7 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain ISP1_C PF18161.1 ORY05494.1 - 0.055 13.5 0.4 0.096 12.7 0.4 1.3 1 0 0 1 1 1 0 ISP1 C-terminal ISP3_C PF18045.1 ORY05494.1 - 0.055 13.3 0.4 0.1 12.5 0.4 1.4 1 0 0 1 1 1 0 ISP3 C-terminal Aldo_ket_red PF00248.21 ORY05546.1 - 1e-19 70.8 0.0 6.9e-19 68.1 0.0 1.8 1 1 0 1 1 1 1 Aldo/keto reductase family DUF273 PF03314.14 ORY05547.1 - 0.00015 21.4 0.1 0.00066 19.3 0.1 1.9 1 1 0 1 1 1 1 Protein of unknown function, DUF273 Glyco_transf_34 PF05637.12 ORY05547.1 - 0.00064 19.5 1.9 0.0026 17.5 1.9 1.8 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Nucleotid_trans PF03407.16 ORY05547.1 - 0.0039 17.2 0.3 0.0051 16.8 0.3 1.3 1 1 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Amidohydro_3 PF07969.11 ORY05548.1 - 1.1e-32 114.2 0.2 1.7e-32 113.5 0.2 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 ORY05548.1 - 4.7e-09 36.0 0.1 3.1e-05 23.4 0.0 3.0 3 0 0 3 3 3 2 Amidohydrolase family MARVEL PF01284.23 ORY05549.1 - 5.4e-08 33.0 2.7 5.4e-08 33.0 2.7 2.1 1 1 1 2 2 2 1 Membrane-associating domain AgrB PF04647.15 ORY05549.1 - 0.0048 16.2 1.1 0.0048 16.2 1.1 2.2 3 0 0 3 3 3 1 Accessory gene regulator B Vma12 PF11712.8 ORY05549.1 - 0.022 14.8 7.6 2.1 8.4 1.2 3.2 3 0 0 3 3 3 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF4234 PF14018.6 ORY05549.1 - 0.075 13.2 8.1 6.1 7.1 5.0 3.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4234) DUF3810 PF12725.7 ORY05549.1 - 0.08 12.3 4.9 0.053 12.9 1.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) Wzy_C_2 PF11846.8 ORY05549.1 - 0.38 10.7 4.3 2.3 8.1 1.7 2.3 2 0 0 2 2 2 0 Virulence factor membrane-bound polymerase, C-terminal Activator-TraM PF11657.8 ORY05549.1 - 0.56 10.0 6.0 0.51 10.2 4.3 1.8 2 0 0 2 2 2 0 Transcriptional activator TraM Bac_rhodopsin PF01036.18 ORY05549.1 - 0.71 9.4 14.4 0.064 12.8 3.5 3.0 2 1 1 3 3 3 0 Bacteriorhodopsin-like protein Shisa PF13908.6 ORY05549.1 - 3.1 8.0 9.7 0.13 12.5 1.6 2.6 2 1 1 3 3 3 0 Wnt and FGF inhibitory regulator DUF2207 PF09972.9 ORY05549.1 - 5.1 5.7 8.4 28 3.3 8.4 2.1 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Ceramidase PF05875.12 ORY05549.1 - 6.1 6.2 9.4 0.8 9.1 5.2 1.6 2 0 0 2 2 2 0 Ceramidase LIP PF03583.14 ORY05550.1 - 2.2e-31 109.2 0.0 3.1e-31 108.8 0.0 1.1 1 0 0 1 1 1 1 Secretory lipase PPR_2 PF13041.6 ORY05551.1 - 1.7e-14 53.7 0.0 0.00024 21.2 0.0 4.4 4 0 0 4 4 4 3 PPR repeat family PPR PF01535.20 ORY05551.1 - 4.1e-11 42.4 0.2 0.0047 17.1 0.0 4.5 5 0 0 5 5 5 3 PPR repeat PPR_3 PF13812.6 ORY05551.1 - 7.3e-08 32.4 0.1 0.1 12.7 0.0 4.0 4 0 0 4 4 4 2 Pentatricopeptide repeat domain PPR_1 PF12854.7 ORY05551.1 - 5e-05 22.9 1.0 0.64 9.8 0.0 4.0 3 1 0 3 3 3 2 PPR repeat MRP-S25 PF13741.6 ORY05552.1 - 1.7e-65 220.8 1.1 1.8e-58 197.8 0.8 2.0 1 1 1 2 2 2 2 Mitochondrial ribosomal protein S25 NACHT PF05729.12 ORY05553.1 - 9.2e-13 48.4 0.1 3.1e-12 46.7 0.0 1.9 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 ORY05553.1 - 3.1e-05 24.4 2.5 3.6e-05 24.2 0.1 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.6 ORY05553.1 - 0.0012 18.9 0.0 0.13 12.2 0.0 2.8 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 ORY05553.1 - 0.0036 17.6 0.0 0.013 15.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 ORY05553.1 - 0.022 15.2 0.0 0.073 13.5 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 ORY05553.1 - 0.023 13.9 0.0 0.047 12.9 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain DUF2075 PF09848.9 ORY05553.1 - 0.045 13.0 0.0 0.084 12.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) KAP_NTPase PF07693.14 ORY05553.1 - 0.1 11.8 0.3 3.3 6.9 0.0 2.6 2 1 1 3 3 3 0 KAP family P-loop domain Neur_chan_memb PF02932.16 ORY05553.1 - 0.3 11.1 1.5 0.82 9.7 0.0 2.3 3 0 0 3 3 3 0 Neurotransmitter-gated ion-channel transmembrane region CDH-cyt PF16010.5 ORY05555.1 - 8e-45 152.8 2.0 1.6e-44 151.8 2.0 1.5 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase SGL PF08450.12 ORY05555.1 - 0.021 14.4 0.7 0.085 12.4 0.1 2.3 2 1 0 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region PD40 PF07676.12 ORY05555.1 - 0.06 13.3 0.1 0.53 10.3 0.0 2.6 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Lamp PF01299.17 ORY05555.1 - 0.096 12.5 0.0 0.25 11.2 0.0 1.6 2 0 0 2 2 2 0 Lysosome-associated membrane glycoprotein (Lamp) Str_synth PF03088.16 ORY05555.1 - 0.13 12.4 0.0 0.49 10.6 0.0 2.0 2 0 0 2 2 2 0 Strictosidine synthase NHL PF01436.21 ORY05555.1 - 0.34 11.0 1.3 2 8.6 0.1 2.8 3 0 0 3 3 3 0 NHL repeat FMO-like PF00743.19 ORY05556.1 - 4.9e-15 55.0 0.1 7.2e-14 51.1 0.1 2.5 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 ORY05556.1 - 3.2e-11 43.1 0.0 6.8e-11 42.0 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ORY05556.1 - 2.5e-09 36.8 0.0 3e-07 30.0 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ORY05556.1 - 7.7e-08 31.8 0.1 2.1e-05 23.9 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 ORY05556.1 - 2.7e-07 30.7 0.1 1.2e-05 25.4 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 ORY05556.1 - 0.0002 20.7 0.0 0.0005 19.4 0.0 1.5 1 0 0 1 1 1 1 Thi4 family Shikimate_DH PF01488.20 ORY05556.1 - 0.00085 19.4 0.1 0.0067 16.5 0.0 2.3 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase DAO PF01266.24 ORY05556.1 - 0.0016 18.1 6.7 0.0065 16.1 0.1 3.7 4 1 0 4 4 4 1 FAD dependent oxidoreductase Mqo PF06039.15 ORY05556.1 - 0.0039 15.8 0.0 1.7 7.1 0.0 2.1 2 0 0 2 2 2 2 Malate:quinone oxidoreductase (Mqo) GIDA PF01134.22 ORY05556.1 - 0.04 13.0 1.4 2.6 7.0 0.1 2.4 3 0 0 3 3 3 0 Glucose inhibited division protein A Pyr_redox PF00070.27 ORY05556.1 - 0.26 11.9 1.2 13 6.4 0.2 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase zf-Di19 PF05605.12 ORY05557.1 - 0.072 13.4 7.6 0.09 13.1 1.6 3.5 4 0 0 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding Auts2 PF15336.6 ORY05557.1 - 0.18 11.9 2.2 0.29 11.2 0.1 2.2 2 0 0 2 2 2 0 Autism susceptibility gene 2 protein DUF4451 PF14616.6 ORY05557.1 - 0.33 11.2 9.3 4.3 7.5 0.4 3.7 2 1 2 4 4 4 0 Domain of unknown function (DUF4451) HET PF06985.11 ORY05559.1 - 2e-32 112.5 0.0 3.2e-32 111.9 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) A_deamin PF02137.18 ORY05560.1 - 0.048 13.1 0.1 0.059 12.8 0.1 1.2 1 0 0 1 1 1 0 Adenosine-deaminase (editase) domain Lipase_GDSL_2 PF13472.6 ORY05562.1 - 1.5e-07 32.0 0.0 4.3e-07 30.5 0.0 1.7 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 ORY05562.1 - 1.9e-05 24.7 0.0 2.6e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase AA_permease_2 PF13520.6 ORY05563.1 - 6.8e-49 166.8 49.0 8.9e-49 166.5 49.0 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ORY05563.1 - 2.1e-21 76.1 37.2 3e-21 75.6 37.2 1.1 1 0 0 1 1 1 1 Amino acid permease CTP_transf_like PF01467.26 ORY05567.1 - 4e-22 79.0 0.0 3.5e-21 75.9 0.0 2.4 2 1 0 2 2 2 1 Cytidylyltransferase-like Acetyltransf_1 PF00583.25 ORY05570.1 - 1.4e-11 44.7 0.0 2e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 ORY05570.1 - 4.5e-08 32.9 0.1 8.1e-08 32.1 0.1 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 ORY05570.1 - 6.3e-08 32.6 0.1 8.9e-08 32.1 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ORY05570.1 - 9e-05 22.8 0.0 0.00015 22.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 ORY05570.1 - 0.0075 16.3 0.2 0.015 15.4 0.2 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 ORY05570.1 - 0.022 14.2 0.1 0.033 13.7 0.0 1.3 2 0 0 2 2 2 0 Putative acetyl-transferase Spc24 PF08286.11 ORY05570.1 - 0.24 11.6 1.3 2.1 8.7 0.4 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Zn_clus PF00172.18 ORY05571.1 - 4.9e-10 39.4 13.5 8.7e-10 38.6 13.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Opy2 PF09463.10 ORY05571.1 - 4.5 7.7 8.8 0.26 11.6 3.1 1.8 2 0 0 2 2 2 0 Opy2 protein p450 PF00067.22 ORY05572.1 - 6.1e-76 256.0 0.0 8e-76 255.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.20 ORY05572.1 - 2.7e-28 99.1 0.0 4.1e-28 98.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 ORY05572.1 - 6.6e-25 88.0 0.1 1.7e-24 86.7 0.1 1.7 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 ORY05572.1 - 1.9e-13 51.0 0.0 8.6e-13 48.9 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 ORY05572.1 - 0.00039 20.7 0.0 0.00098 19.4 0.0 1.7 1 0 0 1 1 1 1 Flavodoxin domain Flavodoxin_3 PF12641.7 ORY05572.1 - 0.038 13.7 0.0 0.089 12.5 0.0 1.6 1 0 0 1 1 1 0 Flavodoxin domain Flavodoxin_NdrI PF07972.11 ORY05572.1 - 0.04 14.1 0.0 0.083 13.1 0.0 1.5 1 0 0 1 1 1 0 NrdI Flavodoxin like ACOX PF01756.19 ORY05573.1 - 1.1e-40 139.1 0.9 3.2e-40 137.6 0.1 2.1 3 0 0 3 3 3 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 ORY05573.1 - 1e-25 90.7 1.1 2.8e-25 89.3 0.8 2.0 2 0 0 2 2 2 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 ORY05573.1 - 1e-09 38.4 0.0 3.7e-09 36.7 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 ORY05573.1 - 0.027 14.7 0.7 0.28 11.4 0.7 2.4 1 1 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain Transferase PF02458.15 ORY05574.1 - 8.1e-21 74.2 0.0 5.4e-15 55.0 0.0 2.2 2 0 0 2 2 2 2 Transferase family AMP-binding PF00501.28 ORY05576.1 - 7.5e-60 202.7 0.0 1.1e-59 202.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORY05576.1 - 3.1e-13 50.5 0.0 6.7e-13 49.4 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain RPAP1_N PF08621.10 ORY05576.1 - 0.023 14.5 0.0 0.062 13.1 0.0 1.7 1 0 0 1 1 1 0 RPAP1-like, N-terminal DLH PF01738.18 ORY05577.1 - 3.2e-22 79.1 0.1 4.2e-22 78.8 0.1 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Zn_clus PF00172.18 ORY05578.1 - 4.3e-08 33.2 8.4 9.7e-08 32.0 8.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RTA1 PF04479.13 ORY05579.1 - 4.6e-58 196.2 5.6 4.6e-58 196.2 5.6 1.6 2 0 0 2 2 2 1 RTA1 like protein Fungal_trans PF04082.18 ORY05580.1 - 1.5e-07 30.7 0.0 3.2e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY05580.1 - 1.6e-05 24.9 10.7 2.8e-05 24.1 10.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ECH_1 PF00378.20 ORY05581.1 - 2e-23 83.0 0.0 2.2e-23 82.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ORY05581.1 - 1.1e-11 44.8 0.0 1.3e-11 44.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Tyrosinase PF00264.20 ORY05582.1 - 7.7e-52 176.8 0.2 9.8e-52 176.4 0.2 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase Cypo_polyhedrin PF05865.11 ORY05583.1 - 0.071 12.5 0.0 0.095 12.1 0.0 1.1 1 0 0 1 1 1 0 Cypovirus polyhedrin protein SSL_OB PF09199.10 ORY05584.1 - 0.2 12.0 0.0 0.37 11.1 0.0 1.3 1 0 0 1 1 1 0 Staphylococcal superantigen-like OB-fold domain NDUFB10 PF10249.9 ORY05673.1 - 0.00059 20.3 0.0 0.00066 20.2 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 HWE_HK PF07536.14 ORY05673.1 - 0.025 15.3 0.0 0.035 14.8 0.0 1.2 1 0 0 1 1 1 0 HWE histidine kinase BRO1 PF03097.18 ORY05674.1 - 4.2e-08 32.4 0.0 9.8e-08 31.2 0.0 1.4 1 1 0 1 1 1 1 BRO1-like domain AA_permease_2 PF13520.6 ORY05675.1 - 1e-59 202.5 55.9 1.3e-59 202.2 55.9 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ORY05675.1 - 3.7e-14 52.2 40.9 5.4e-14 51.7 40.9 1.2 1 0 0 1 1 1 1 Amino acid permease SH3BGR PF04908.15 ORY05676.1 - 0.00031 20.9 0.0 0.0044 17.2 0.0 2.9 2 0 0 2 2 2 1 SH3-binding, glutamic acid-rich protein bZIP_1 PF00170.21 ORY05677.1 - 4.1e-06 26.8 9.6 6.8e-06 26.1 9.6 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 ORY05677.1 - 0.004 17.2 2.9 0.004 17.2 2.9 1.6 2 0 0 2 2 2 1 Basic region leucine zipper Myelin_PLP PF01275.19 ORY05677.1 - 0.026 14.4 0.1 0.038 13.8 0.1 1.2 1 0 0 1 1 1 0 Myelin proteolipid protein (PLP or lipophilin) Aldo_ket_red PF00248.21 ORY05680.1 - 1.2e-64 218.3 0.0 1.4e-64 218.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family OPA3 PF07047.12 ORY05683.1 - 3.1e-47 159.5 4.6 4.6e-47 158.9 4.6 1.3 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) S_4TM PF18159.1 ORY05683.1 - 0.01 15.2 0.0 0.022 14.1 0.0 1.5 1 0 0 1 1 1 0 SMODS-associating 4TM effector domain DivIC PF04977.15 ORY05683.1 - 0.027 14.3 0.4 0.027 14.3 0.4 2.4 2 1 0 2 2 2 0 Septum formation initiator Med11 PF10280.9 ORY05683.1 - 0.089 13.3 1.9 0.44 11.0 1.9 2.3 1 1 0 1 1 1 0 Mediator complex protein Golgin_A5 PF09787.9 ORY05683.1 - 0.12 11.8 7.0 0.058 12.8 1.1 2.1 2 0 0 2 2 2 0 Golgin subfamily A member 5 DUF5320 PF17253.2 ORY05683.1 - 0.39 11.8 3.5 2.2 9.4 0.2 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5320) EAP30 PF04157.16 ORY05683.1 - 0.44 9.8 2.6 6.1 6.0 0.2 2.3 2 1 0 2 2 2 0 EAP30/Vps36 family DUF2681 PF10883.8 ORY05683.1 - 0.44 11.0 0.2 0.44 11.0 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) Peptidase_S49_N PF08496.10 ORY05683.1 - 0.59 10.2 0.0 0.59 10.2 0.0 2.3 2 1 0 2 2 2 0 Peptidase family S49 N-terminal Spc24 PF08286.11 ORY05683.1 - 0.69 10.2 5.5 0.25 11.6 0.3 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 DUF3306 PF11748.8 ORY05683.1 - 2.1 9.2 11.2 4.6 8.1 2.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) Tho2 PF11262.8 ORY05683.1 - 8.7 5.4 9.3 0.39 9.9 0.6 2.5 3 0 0 3 3 3 0 Transcription factor/nuclear export subunit protein 2 Myosin_head PF00063.21 ORY05684.1 - 4e-243 808.6 6.2 5e-243 808.3 6.2 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Pkinase PF00069.25 ORY05684.1 - 2.9e-62 210.4 0.0 6e-62 209.4 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Myosin_TH1 PF06017.13 ORY05684.1 - 1.6e-51 174.7 0.0 2.8e-51 173.9 0.0 1.5 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding Pkinase_Tyr PF07714.17 ORY05684.1 - 1.5e-43 149.0 0.0 2.6e-43 148.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase SH3_1 PF00018.28 ORY05684.1 - 1.1e-12 47.3 0.1 2.2e-12 46.3 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 ORY05684.1 - 2.5e-11 43.3 0.1 2.3e-10 40.1 0.0 2.5 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 ORY05684.1 - 1e-08 34.7 0.0 2.6e-08 33.4 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain POLO_box PF00659.18 ORY05684.1 - 6.6e-06 26.2 0.0 0.00071 19.7 0.0 2.6 2 0 0 2 2 2 1 POLO box duplicated region Kinase-like PF14531.6 ORY05684.1 - 5.5e-05 22.6 0.0 0.00011 21.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like IQ PF00612.27 ORY05684.1 - 0.013 15.2 7.8 0.69 9.9 0.4 2.7 2 0 0 2 2 2 0 IQ calmodulin-binding motif AAA_22 PF13401.6 ORY05684.1 - 0.019 15.3 0.0 0.083 13.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain Kdo PF06293.14 ORY05684.1 - 0.051 12.9 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ABC_tran PF00005.27 ORY05684.1 - 0.14 12.7 0.1 0.48 10.9 0.1 2.0 1 0 0 1 1 1 0 ABC transporter Hpr_kinase_C PF07475.12 ORY05684.1 - 0.17 11.4 0.3 18 4.8 0.1 2.7 3 0 0 3 3 3 0 HPr Serine kinase C-terminal domain Pkinase_fungal PF17667.1 ORY05684.1 - 0.18 10.5 0.0 0.36 9.5 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Glyco_hydro_3_C PF01915.22 ORY05686.1 - 9.5e-67 224.9 0.0 2.7e-66 223.4 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 ORY05686.1 - 1e-53 182.8 0.0 1.9e-53 181.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain PA14 PF07691.12 ORY05686.1 - 7.9e-21 74.4 0.0 1.4e-20 73.6 0.0 1.4 1 0 0 1 1 1 1 PA14 domain Fn3-like PF14310.6 ORY05686.1 - 8.7e-20 70.6 0.4 2.5e-19 69.1 0.0 1.9 2 0 0 2 2 2 1 Fibronectin type III-like domain Sin3a_C PF16879.5 ORY05687.1 - 3.5e-64 217.3 5.1 3.5e-64 217.3 5.1 3.5 4 0 0 4 4 4 1 C-terminal domain of Sin3a protein PAH PF02671.21 ORY05687.1 - 3.1e-42 142.4 8.4 2.7e-17 62.6 1.8 5.0 4 1 1 5 5 5 3 Paired amphipathic helix repeat Sin3_corepress PF08295.12 ORY05687.1 - 4.5e-41 138.9 0.1 1.1e-40 137.6 0.1 1.7 1 0 0 1 1 1 1 Sin3 family co-repressor Thioredoxin_4 PF13462.6 ORY05688.1 - 3.9e-06 27.1 0.0 1.3e-05 25.4 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin DSBA PF01323.20 ORY05688.1 - 0.011 15.5 0.2 1.5 8.5 0.0 2.6 2 1 0 2 2 2 0 DSBA-like thioredoxin domain Glyco_hydro_3_C PF01915.22 ORY05689.1 - 4.8e-39 134.4 0.0 8.2e-39 133.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 ORY05689.1 - 8.3e-34 117.4 0.0 1.2e-33 116.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 ORY05689.1 - 1.9e-05 24.7 0.0 4.5e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain p450 PF00067.22 ORY05690.1 - 6.5e-56 190.0 0.2 8.9e-56 189.5 0.2 1.1 1 0 0 1 1 1 1 Cytochrome P450 Lactamase_B PF00753.27 ORY05691.1 - 3.1e-07 30.6 0.1 5.8e-07 29.7 0.1 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 ORY05691.1 - 0.0024 17.4 0.0 0.0035 16.9 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 ORY05691.1 - 0.18 11.7 0.0 0.34 10.8 0.0 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain COesterase PF00135.28 ORY05692.1 - 2.2e-56 191.8 0.0 2.8e-56 191.4 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 ORY05692.1 - 1.1e-06 28.7 0.2 2.8e-05 24.1 0.2 2.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 ORY05692.1 - 0.027 14.0 0.0 0.074 12.5 0.0 1.7 1 0 0 1 1 1 0 Prolyl oligopeptidase family adh_short PF00106.25 ORY05693.1 - 1.5e-39 135.5 0.2 2.1e-39 135.0 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY05693.1 - 1.2e-30 106.9 0.0 1.6e-30 106.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY05693.1 - 4e-05 23.6 0.2 0.0084 16.0 0.2 2.4 2 1 0 2 2 2 2 KR domain NAD_binding_11 PF14833.6 ORY05694.1 - 1.5e-27 96.2 0.0 2.6e-27 95.5 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.15 ORY05694.1 - 2.1e-20 73.5 0.0 3.1e-20 72.9 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_10 PF13460.6 ORY05695.1 - 2.3e-11 43.9 0.0 1.7e-09 37.9 0.0 2.1 1 1 1 2 2 2 2 NAD(P)H-binding Epimerase PF01370.21 ORY05695.1 - 0.00017 21.2 0.0 0.00026 20.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ORY05695.1 - 0.017 14.5 0.0 0.025 14.0 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase CoA_trans PF01144.23 ORY05696.1 - 2.4e-94 314.8 7.9 4.6e-56 189.6 0.9 2.2 2 0 0 2 2 2 2 Coenzyme A transferase Fe-ADH PF00465.19 ORY05696.1 - 2.6e-67 227.2 0.4 4.8e-67 226.3 0.4 1.3 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 ORY05696.1 - 1.8e-17 63.9 0.1 4e-17 62.7 0.1 1.6 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase KGG PF10685.9 ORY05696.1 - 2.4 8.5 4.3 1.1 9.6 0.8 2.3 2 0 0 2 2 2 0 Stress-induced bacterial acidophilic repeat motif Thiolase_N PF00108.23 ORY05697.1 - 4.7e-73 245.8 0.1 5.8e-72 242.2 0.0 2.1 2 1 1 3 3 3 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 ORY05697.1 - 3.7e-44 149.3 0.4 9.6e-44 148.0 0.1 1.8 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 ORY05697.1 - 4.2e-05 23.3 0.1 9e-05 22.2 0.1 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Lyase_1 PF00206.20 ORY05698.1 - 2e-45 155.5 0.0 3.4e-45 154.8 0.0 1.3 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 ORY05698.1 - 3.6e-22 78.7 0.0 5e-20 71.8 0.0 2.7 2 0 0 2 2 2 2 Adenylosuccinate lyase C-terminus HgmA PF04209.13 ORY05699.1 - 3.3e-138 461.0 0.0 4e-138 460.7 0.0 1.1 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase CoA_transf_3 PF02515.17 ORY05700.1 - 2.6e-125 418.4 0.0 3e-125 418.2 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III Mito_carr PF00153.27 ORY05701.1 - 8.4e-63 208.3 1.0 1e-23 83.0 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein PT-VENN PF04829.13 ORY05701.1 - 0.7 10.0 0.1 0.7 10.0 0.1 2.4 3 0 0 3 3 3 0 Pre-toxin domain with VENN motif Fungal_trans PF04082.18 ORY05702.1 - 1.1e-12 47.5 0.7 1.1e-12 47.5 0.7 2.0 3 0 0 3 3 3 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.6 ORY05702.1 - 7.7e-06 26.1 14.7 2.6e-05 24.4 7.9 2.7 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2 PF00096.26 ORY05702.1 - 0.0032 17.9 17.7 0.11 12.9 4.1 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-met PF12874.7 ORY05702.1 - 0.0032 17.8 10.2 0.14 12.6 1.5 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 ORY05702.1 - 0.0062 17.3 15.3 0.43 11.5 3.2 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger C1_4 PF07975.12 ORY05702.1 - 0.2 11.9 3.4 0.4 11.0 3.4 1.5 1 0 0 1 1 1 0 TFIIH C1-like domain zf-C2H2_jaz PF12171.8 ORY05702.1 - 1.1 9.7 17.4 0.077 13.3 1.1 2.8 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.10 ORY05702.1 - 1.9 8.7 3.7 4.6 7.5 3.7 1.6 1 0 0 1 1 1 0 Zinc ribbon domain zf-C2HC_2 PF13913.6 ORY05702.1 - 3.6 7.6 9.4 2.1 8.3 0.5 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_6 PF13912.6 ORY05702.1 - 9.6 6.3 11.4 1.5 8.9 3.9 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger p450 PF00067.22 ORY05703.1 - 4.3e-66 223.6 0.0 5.4e-66 223.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 TMF_TATA_bd PF12325.8 ORY05704.1 - 0.036 14.3 0.9 0.036 14.3 0.9 2.4 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding DUF2353 PF09789.9 ORY05704.1 - 0.074 12.4 1.0 0.15 11.4 1.0 1.5 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) DUF924 PF06041.11 ORY05706.1 - 1.2e-47 162.4 0.0 1.5e-47 162.1 0.0 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF924) Abhydrolase_3 PF07859.13 ORY05707.1 - 2.1e-23 83.3 0.0 7.6e-23 81.5 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 ORY05707.1 - 0.042 12.7 0.0 0.053 12.4 0.0 1.2 1 0 0 1 1 1 0 Steryl acetyl hydrolase TPR_12 PF13424.6 ORY05708.1 - 0.00044 20.5 0.2 0.00044 20.5 0.2 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 ORY05708.1 - 0.0021 17.8 0.9 0.0021 17.8 0.9 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 ORY05708.1 - 0.003 17.5 7.7 0.13 12.4 0.4 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 ORY05708.1 - 0.061 13.6 0.9 0.99 9.8 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat RVT_3 PF13456.6 ORY05708.1 - 0.13 12.0 0.1 0.66 9.8 0.1 2.2 2 0 0 2 2 2 0 Reverse transcriptase-like ANAPC3 PF12895.7 ORY05708.1 - 0.28 11.4 1.8 0.95 9.7 0.6 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 PNP_UDP_1 PF01048.20 ORY05710.1 - 0.018 14.3 1.8 0.053 12.8 1.8 1.9 1 1 0 1 1 1 0 Phosphorylase superfamily FA_desaturase PF00487.24 ORY05712.1 - 1.9e-23 83.6 22.2 2.8e-23 83.1 22.2 1.2 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 ORY05712.1 - 0.028 14.6 0.0 0.058 13.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3474) MFS_1 PF07690.16 ORY05713.1 - 3.5e-30 105.1 47.9 4.2e-29 101.6 42.7 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 ORY05713.1 - 0.32 9.2 9.1 0.086 11.1 0.9 2.6 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family adh_short PF00106.25 ORY05714.1 - 3.4e-05 23.4 0.1 0.0001 21.9 0.1 1.7 2 0 0 2 2 2 1 short chain dehydrogenase AAA_16 PF13191.6 ORY05714.1 - 0.017 15.5 0.1 8.5 6.7 0.1 2.4 2 1 0 2 2 2 0 AAA ATPase domain HHH_2 PF12826.7 ORY05715.1 - 0.088 12.9 0.1 0.16 12.1 0.1 1.4 1 0 0 1 1 1 0 Helix-hairpin-helix motif GST_C PF00043.25 ORY05716.1 - 3.6e-11 43.1 0.2 5.5e-11 42.5 0.2 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 ORY05716.1 - 5.9e-08 32.8 0.0 1.3e-07 31.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 ORY05716.1 - 3.8e-07 30.4 0.0 1.2e-06 28.8 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 ORY05716.1 - 2.3e-05 24.3 0.1 4.5e-05 23.4 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 ORY05716.1 - 0.0059 17.0 0.0 0.015 15.7 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 ORY05716.1 - 0.026 14.8 0.0 0.049 13.9 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Lactamase_B_2 PF12706.7 ORY05717.1 - 2.1e-33 115.5 0.0 9.5e-33 113.4 0.0 1.9 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 ORY05717.1 - 1.5e-10 41.2 0.0 3.2e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 ORY05717.1 - 0.037 14.0 0.1 1.1 9.3 0.1 2.4 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily Ribonuclease_T2 PF00445.18 ORY05718.1 - 4.3e-32 111.8 0.0 5.6e-32 111.4 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease T2 family TPR_1 PF00515.28 ORY05719.1 - 5.7e-23 79.7 0.7 8.6e-08 31.7 0.0 5.7 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 ORY05719.1 - 4.9e-21 73.1 1.1 7.6e-06 25.7 0.0 5.9 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 ORY05719.1 - 2.7e-19 68.6 3.4 1.7e-07 30.8 0.0 4.7 4 1 0 4 4 4 3 TPR repeat TPR_16 PF13432.6 ORY05719.1 - 7.9e-18 64.8 3.7 5.4e-06 27.0 0.9 4.5 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 ORY05719.1 - 7.9e-15 54.3 4.8 5.1e-05 23.8 0.0 5.5 2 2 3 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 ORY05719.1 - 2.8e-14 53.4 2.5 0.0022 18.5 0.0 4.5 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 ORY05719.1 - 1.5e-12 46.7 0.4 0.00041 20.4 0.0 4.9 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 ORY05719.1 - 8.2e-12 44.6 0.2 0.78 10.3 0.0 5.0 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_9 PF13371.6 ORY05719.1 - 1e-09 38.4 0.7 0.003 17.7 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 ORY05719.1 - 1.2e-09 37.5 1.4 0.046 13.8 0.0 5.9 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 ORY05719.1 - 1.8e-09 37.7 0.5 0.00019 21.6 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_20 PF14561.6 ORY05719.1 - 4.7e-08 33.3 0.7 0.0061 16.9 0.0 4.4 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_6 PF13174.6 ORY05719.1 - 2e-06 28.0 1.8 2.6 8.9 0.1 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY05719.1 - 6.2e-05 23.1 1.1 0.016 15.4 0.1 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 ORY05719.1 - 0.0012 18.2 3.0 0.18 11.0 0.9 2.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_3 PF07720.12 ORY05719.1 - 0.002 18.1 0.1 1.4 9.0 0.0 3.1 4 0 0 4 4 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 ORY05719.1 - 0.034 14.0 1.0 14 5.7 0.2 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat RRM_1 PF00076.22 ORY05720.1 - 3.2e-37 126.2 0.4 3.1e-21 75.0 0.1 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 ORY05720.1 - 3.5e-06 26.6 0.0 0.0052 16.4 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 ORY05720.1 - 0.001 18.9 0.0 0.065 13.1 0.0 2.4 2 1 0 2 2 2 1 Occluded RNA-recognition motif RRM_7 PF16367.5 ORY05720.1 - 0.017 15.2 0.1 0.35 11.0 0.0 2.7 2 1 0 2 2 2 0 RNA recognition motif DUF2960 PF11173.8 ORY05720.1 - 0.021 15.3 0.0 0.049 14.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2960) RRM_8 PF11835.8 ORY05720.1 - 0.11 12.8 0.2 0.38 11.0 0.0 2.0 2 0 0 2 2 2 0 RRM-like domain SH3_9 PF14604.6 ORY05793.1 - 1.9e-13 50.0 0.5 2.6e-13 49.6 0.5 1.2 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 ORY05793.1 - 9.1e-13 47.6 0.3 1.2e-12 47.2 0.3 1.2 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 ORY05793.1 - 4.9e-10 38.9 0.0 6.7e-10 38.5 0.0 1.2 1 0 0 1 1 1 1 Variant SH3 domain RPAP2_Rtr1 PF04181.13 ORY05794.1 - 3.8e-22 78.4 0.1 6.6e-22 77.6 0.1 1.4 1 0 0 1 1 1 1 Rtr1/RPAP2 family Mit_ribos_Mrp51 PF11709.8 ORY05795.1 - 8.5e-109 364.5 0.5 1.2e-108 364.0 0.5 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit Potyvirid-P3 PF13608.6 ORY05795.1 - 0.053 12.6 0.2 0.083 11.9 0.2 1.2 1 0 0 1 1 1 0 Protein P3 of Potyviral polyprotein MFS_1 PF07690.16 ORY05798.1 - 1.9e-37 129.1 45.8 1.9e-37 129.1 45.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY05798.1 - 1.8e-09 37.0 23.5 2.2e-08 33.4 24.0 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter Pam17 PF08566.10 ORY05798.1 - 4.7 7.0 4.6 0.97 9.3 0.5 1.9 2 0 0 2 2 2 0 Mitochondrial import protein Pam17 ParBc_2 PF08857.11 ORY05800.1 - 0.086 12.9 0.3 0.19 11.8 0.2 1.5 1 1 0 1 1 1 0 Putative ParB-like nuclease DUF2457 PF10446.9 ORY05800.1 - 2.5 7.1 14.0 5.7 6.0 14.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) TBSV_P22 PF03558.13 ORY05803.1 - 4.4 6.7 6.0 2.6 7.5 2.0 2.1 2 0 0 2 2 2 0 TBSV core protein P21/P22 peroxidase PF00141.23 ORY05807.1 - 4e-27 95.4 0.0 7.1e-27 94.6 0.0 1.3 1 0 0 1 1 1 1 Peroxidase zf-AN1 PF01428.16 ORY05809.1 - 2.1e-23 82.2 21.6 6.2e-12 45.5 7.6 2.2 2 0 0 2 2 2 2 AN1-like Zinc finger Phage_Mu_Gam PF07352.12 ORY05809.1 - 0.0084 16.0 0.3 0.013 15.4 0.3 1.2 1 0 0 1 1 1 1 Bacteriophage Mu Gam like protein IBR PF01485.21 ORY05809.1 - 0.033 14.4 4.7 0.033 14.4 4.7 2.5 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain Transp_Tc5_C PF04236.15 ORY05809.1 - 0.46 10.9 15.9 1.8 9.0 2.0 2.3 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain HET PF06985.11 ORY05810.1 - 7.2e-36 123.7 1.0 1.1e-35 123.1 1.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HET PF06985.11 ORY05811.1 - 4.5e-36 124.4 1.8 7.9e-36 123.6 1.8 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MTP18 PF10558.9 ORY05815.1 - 1.1e-79 266.3 0.1 1.7e-79 265.7 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) ATP19 PF11022.8 ORY05816.1 - 3e-24 85.2 0.4 3.3e-24 85.0 0.4 1.0 1 0 0 1 1 1 1 ATP synthase subunit K Csm1 PF12539.8 ORY05817.1 - 1.1e-32 112.4 0.0 2.4e-32 111.4 0.0 1.6 1 0 0 1 1 1 1 Chromosome segregation protein Csm1/Pcs1 YabA PF06156.13 ORY05817.1 - 0.00012 22.6 7.3 0.00034 21.2 3.7 2.4 1 1 1 2 2 2 1 Initiation control protein YabA CALCOCO1 PF07888.11 ORY05817.1 - 0.00033 19.6 6.4 0.00045 19.2 6.4 1.2 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like DUF5094 PF17015.5 ORY05817.1 - 0.00066 19.8 6.5 0.0014 18.7 0.0 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF5094) CENP-H PF05837.12 ORY05817.1 - 0.0012 19.2 6.5 0.0044 17.4 3.7 2.5 2 0 0 2 2 2 1 Centromere protein H (CENP-H) APG6_N PF17675.1 ORY05817.1 - 0.0025 18.3 10.0 0.0025 18.3 10.0 1.5 2 0 0 2 2 1 1 Apg6 coiled-coil region UPF0242 PF06785.11 ORY05817.1 - 0.0065 16.6 11.5 0.053 13.6 5.1 2.2 1 1 1 2 2 2 2 Uncharacterised protein family (UPF0242) N-terminus FAM184 PF15665.5 ORY05817.1 - 0.0088 15.8 6.7 0.016 15.0 6.7 1.4 1 0 0 1 1 1 1 Family with sequence similarity 184, A and B GAS PF13851.6 ORY05817.1 - 0.009 15.4 12.5 0.052 12.9 6.2 2.5 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding DUF480 PF04337.12 ORY05817.1 - 0.014 15.5 2.5 0.026 14.6 2.5 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF480 PRKG1_interact PF15898.5 ORY05817.1 - 0.015 16.2 12.8 0.043 14.7 7.5 2.4 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain KASH_CCD PF14662.6 ORY05817.1 - 0.019 14.8 2.3 0.019 14.8 2.3 2.3 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH CENP-K PF11802.8 ORY05817.1 - 0.026 14.1 4.4 0.057 13.0 4.4 1.5 1 0 0 1 1 1 0 Centromere-associated protein K Csm1_N PF18504.1 ORY05817.1 - 0.067 13.5 15.5 0.2 12.0 0.5 4.3 3 1 2 5 5 5 0 Csm1 N-terminal domain V_ATPase_I PF01496.19 ORY05817.1 - 0.068 11.1 4.0 0.085 10.8 4.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2205 PF10224.9 ORY05817.1 - 0.072 13.1 3.9 0.18 11.8 3.9 1.7 1 0 0 1 1 1 0 Short coiled-coil protein HAUS-augmin3 PF14932.6 ORY05817.1 - 0.076 12.6 7.9 0.12 11.9 7.9 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 SKA2 PF16740.5 ORY05817.1 - 0.085 12.6 7.3 0.28 11.0 6.4 2.2 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 Wtap PF17098.5 ORY05817.1 - 0.093 12.7 7.5 0.075 13.0 5.7 1.7 2 0 0 2 2 2 0 WTAP/Mum2p family Sigma54_activ_2 PF14532.6 ORY05817.1 - 0.093 12.9 1.2 3.4 7.8 0.7 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain TEX13 PF15186.6 ORY05817.1 - 0.17 11.6 5.5 0.3 10.8 5.5 1.5 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family Spc24 PF08286.11 ORY05817.1 - 0.17 12.1 7.6 0.52 10.6 0.2 2.7 1 1 2 3 3 3 0 Spc24 subunit of Ndc80 Taxilin PF09728.9 ORY05817.1 - 0.23 10.6 13.5 3 6.9 13.5 2.0 1 1 0 1 1 1 0 Myosin-like coiled-coil protein Spc7 PF08317.11 ORY05817.1 - 0.25 10.2 12.7 0.65 8.8 12.7 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein Mt_ATP-synt_B PF05405.14 ORY05817.1 - 0.35 10.5 6.8 0.65 9.6 6.8 1.4 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Filament PF00038.21 ORY05817.1 - 0.35 10.4 9.9 0.052 13.1 6.1 1.5 2 0 0 2 2 1 0 Intermediate filament protein SOGA PF11365.8 ORY05817.1 - 0.38 11.9 9.5 6 8.1 1.8 3.2 1 1 2 3 3 3 0 Protein SOGA Tho2 PF11262.8 ORY05817.1 - 0.39 9.9 3.4 0.66 9.1 3.4 1.5 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DUF724 PF05266.14 ORY05817.1 - 0.51 10.1 8.6 0.97 9.2 8.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF724) TSC22 PF01166.18 ORY05817.1 - 0.67 10.3 4.5 54 4.2 0.0 3.6 2 1 1 3 3 3 0 TSC-22/dip/bun family Fzo_mitofusin PF04799.13 ORY05817.1 - 1 8.9 4.4 0.91 9.1 2.5 1.9 1 1 1 2 2 2 0 fzo-like conserved region ADIP PF11559.8 ORY05817.1 - 1.2 9.2 18.5 0.24 11.5 11.4 2.7 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding Leu_zip PF15294.6 ORY05817.1 - 1.3 8.5 11.5 1.7 8.1 9.0 1.8 1 1 1 2 2 2 0 Leucine zipper ZapB PF06005.12 ORY05817.1 - 1.6 9.2 14.6 24 5.5 2.6 3.2 1 1 1 2 2 2 0 Cell division protein ZapB DUF4407 PF14362.6 ORY05817.1 - 1.9 7.8 12.9 1.7 7.9 11.9 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Fungal_TACC PF12709.7 ORY05817.1 - 2.5 8.6 12.3 2.5 8.6 0.4 3.3 3 0 0 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins Cep57_CLD_2 PF14197.6 ORY05817.1 - 3.5 7.8 14.3 0.33 11.1 7.2 2.8 2 1 1 3 3 2 0 Centrosome localisation domain of PPC89 Bacillus_HBL PF05791.11 ORY05817.1 - 4.5 7.1 10.2 0.93 9.3 3.1 2.4 1 1 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DivIC PF04977.15 ORY05817.1 - 5.2 6.9 14.7 0.74 9.6 4.8 3.3 2 1 1 3 3 3 0 Septum formation initiator Ax_dynein_light PF10211.9 ORY05817.1 - 6.2 6.7 11.5 31 4.4 3.3 2.6 2 1 1 3 3 3 0 Axonemal dynein light chain DUF4164 PF13747.6 ORY05817.1 - 7.1 7.0 10.7 2.1 8.7 7.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) DUF2203 PF09969.9 ORY05817.1 - 9.9 6.9 8.2 6 7.6 1.3 2.6 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2203) adh_short PF00106.25 ORY05820.1 - 2.7e-43 147.7 0.0 3.8e-43 147.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY05820.1 - 4e-23 82.2 0.0 5.7e-23 81.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY05820.1 - 7e-10 39.1 0.0 1.2e-09 38.4 0.0 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 ORY05820.1 - 7.9e-06 25.5 0.0 1.1e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ORY05820.1 - 0.00021 20.8 0.0 0.00025 20.5 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 ORY05820.1 - 0.00055 19.2 0.0 0.00081 18.6 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein F420_oxidored PF03807.17 ORY05820.1 - 0.00072 20.1 0.2 0.0023 18.5 0.2 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3Beta_HSD PF01073.19 ORY05820.1 - 0.02 13.9 0.0 0.039 13.0 0.0 1.6 1 1 1 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Sacchrp_dh_NADP PF03435.18 ORY05820.1 - 0.023 14.9 0.0 0.044 14.0 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NusB PF01029.18 ORY05820.1 - 0.035 14.3 0.1 0.56 10.5 0.0 2.4 2 1 0 2 2 2 0 NusB family Shikimate_DH PF01488.20 ORY05820.1 - 0.068 13.2 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ADH_zinc_N PF00107.26 ORY05820.1 - 0.077 13.0 0.0 0.18 11.8 0.0 1.6 2 0 0 2 2 2 0 Zinc-binding dehydrogenase FAD_binding_3 PF01494.19 ORY05821.1 - 5.8e-89 298.7 0.0 1.2e-88 297.7 0.0 1.5 2 0 0 2 2 2 1 FAD binding domain Chitin_synth_1 PF01644.17 ORY05821.1 - 1.5e-79 265.7 0.0 2.2e-79 265.1 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Phe_hydrox_dim PF07976.12 ORY05821.1 - 1.3e-50 171.6 0.0 2.5e-50 170.8 0.0 1.5 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Chitin_synth_1N PF08407.11 ORY05821.1 - 2.9e-27 94.4 0.1 5.8e-27 93.5 0.1 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 ORY05821.1 - 7.8e-22 77.6 0.2 1.3e-19 70.2 0.0 2.2 1 1 0 2 2 2 1 Chitin synthase Glyco_trans_2_3 PF13632.6 ORY05821.1 - 6.7e-08 32.7 0.6 1.9e-07 31.2 0.6 1.8 1 0 0 1 1 1 1 Glycosyl transferase family group 2 HI0933_like PF03486.14 ORY05821.1 - 0.0011 17.7 0.1 0.0017 17.1 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein Lycopene_cycl PF05834.12 ORY05821.1 - 0.0036 16.4 0.1 0.0059 15.7 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 ORY05821.1 - 0.0039 16.3 0.2 0.0072 15.5 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 ORY05821.1 - 0.0052 16.1 0.1 0.0086 15.4 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ORY05821.1 - 0.014 14.6 0.1 0.03 13.6 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORY05821.1 - 0.015 15.5 0.0 0.06 13.6 0.0 2.1 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 ORY05821.1 - 0.048 12.9 0.0 0.077 12.3 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 ORY05821.1 - 0.11 11.8 0.1 0.29 10.3 0.0 1.7 2 0 0 2 2 2 0 Thi4 family Glyco_tranf_2_3 PF13641.6 ORY05821.1 - 0.16 11.9 0.0 0.48 10.3 0.0 1.8 2 0 0 2 2 2 0 Glycosyltransferase like family 2 NDUFV3 PF15880.5 ORY05822.1 - 0.071 13.1 0.5 0.29 11.2 0.0 2.0 2 0 0 2 2 2 0 NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial DUF302 PF03625.14 ORY05823.1 - 0.045 13.7 0.0 0.075 12.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF302 adh_short_C2 PF13561.6 ORY05824.1 - 9.1e-42 143.2 0.0 4.9e-24 85.2 0.1 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY05824.1 - 6.1e-31 107.4 0.0 6.1e-29 100.9 0.0 2.0 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 ORY05824.1 - 1.7e-13 50.9 0.0 2.5e-13 50.3 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ORY05824.1 - 0.00012 21.7 0.0 0.0002 20.9 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ORY05824.1 - 0.011 15.1 0.0 0.037 13.4 0.0 2.0 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase Acetyltransf_10 PF13673.7 ORY05825.1 - 1e-06 28.7 0.0 2.2e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORY05825.1 - 1.8e-06 28.2 0.0 4.3e-06 26.9 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ORY05825.1 - 6.5e-06 26.5 0.0 1.4e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 ORY05825.1 - 0.00061 19.9 0.0 0.0019 18.3 0.0 1.8 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 ORY05825.1 - 0.028 14.4 0.0 0.064 13.2 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_9 PF13527.7 ORY05825.1 - 0.1 12.7 0.0 1.1 9.3 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Ank_5 PF13857.6 ORY05826.1 - 1.3e-07 31.7 0.8 0.19 12.1 0.1 4.8 6 0 0 6 6 6 2 Ankyrin repeats (many copies) Ank PF00023.30 ORY05826.1 - 9.8e-07 29.0 1.9 0.3 11.6 0.1 4.8 5 0 0 5 5 5 3 Ankyrin repeat Ank_2 PF12796.7 ORY05826.1 - 4e-06 27.3 0.2 0.028 15.0 0.1 4.1 3 1 1 4 4 4 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY05826.1 - 4.5e-06 27.1 1.2 0.21 12.2 0.1 5.8 6 1 1 7 7 7 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY05826.1 - 0.052 14.1 4.8 58 4.8 0.1 5.7 7 0 0 7 7 7 0 Ankyrin repeat Ank_2 PF12796.7 ORY05827.1 - 2e-33 114.8 0.1 3.8e-13 49.8 0.0 3.7 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY05827.1 - 1.5e-21 76.5 0.8 9.3e-09 35.7 0.0 4.5 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY05827.1 - 1.7e-21 74.0 0.6 0.00054 20.2 0.0 6.1 6 0 0 6 6 6 4 Ankyrin repeat Ank PF00023.30 ORY05827.1 - 1.9e-14 53.3 2.7 0.01 16.3 0.1 5.3 4 1 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 ORY05827.1 - 6.2e-12 45.5 2.8 0.008 16.5 0.1 5.0 2 2 3 5 5 5 4 Ankyrin repeats (many copies) NACHT PF05729.12 ORY05828.1 - 2.6e-08 34.0 0.0 2.9e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 NACHT domain DUF2075 PF09848.9 ORY05828.1 - 0.0049 16.2 0.0 0.0049 16.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 ORY05828.1 - 0.0049 16.9 0.0 0.006 16.6 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_16 PF13191.6 ORY05828.1 - 0.0064 16.9 0.0 0.01 16.3 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.22 ORY05828.1 - 0.0068 16.8 0.0 0.0096 16.3 0.0 1.6 1 1 0 1 1 1 1 RNA helicase AAA_22 PF13401.6 ORY05828.1 - 0.013 15.8 0.0 0.018 15.3 0.0 1.5 1 1 0 1 1 1 0 AAA domain APS_kinase PF01583.20 ORY05828.1 - 0.02 14.8 0.0 0.028 14.3 0.0 1.2 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_18 PF13238.6 ORY05828.1 - 0.026 15.1 0.0 0.027 15.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.17 ORY05828.1 - 0.027 14.6 0.0 0.033 14.3 0.0 1.3 1 1 0 1 1 1 0 Helicase HerA, central domain AAA_33 PF13671.6 ORY05828.1 - 0.028 14.6 0.0 0.046 13.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain Ploopntkinase3 PF18751.1 ORY05828.1 - 0.04 13.8 0.0 0.055 13.4 0.0 1.2 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 AAA_17 PF13207.6 ORY05828.1 - 0.071 13.5 0.1 0.11 12.9 0.1 1.3 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.10 ORY05828.1 - 0.072 12.5 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_7 PF12775.7 ORY05828.1 - 0.15 11.6 0.0 7.3 6.1 0.0 2.1 1 1 1 2 2 2 0 P-loop containing dynein motor region DprA_WH PF17782.1 ORY05828.1 - 0.15 12.2 0.0 0.27 11.4 0.0 1.5 1 0 0 1 1 1 0 DprA winged helix domain Mg_chelatase PF01078.21 ORY05828.1 - 0.15 11.4 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NB-ARC PF00931.22 ORY05828.1 - 0.18 11.0 0.0 0.36 10.0 0.0 1.5 2 0 0 2 2 2 0 NB-ARC domain DHO_dh PF01180.21 ORY05829.1 - 1.7e-65 221.1 0.0 5.5e-55 186.6 0.0 2.1 2 0 0 2 2 2 2 Dihydroorotate dehydrogenase PcrB PF01884.17 ORY05829.1 - 0.024 14.1 3.2 0.89 9.0 0.1 2.8 3 0 0 3 3 3 0 PcrB family RmlD_sub_bind PF04321.17 ORY05830.1 - 0.035 13.2 0.8 0.053 12.6 0.8 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain Pro_dh PF01619.18 ORY05832.1 - 0.08 12.5 0.1 0.13 11.8 0.1 1.2 1 0 0 1 1 1 0 Proline dehydrogenase ZZ PF00569.17 ORY05833.1 - 1.7e-10 40.6 4.6 2.9e-10 39.8 4.6 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type SWIRM PF04433.17 ORY05833.1 - 3.6e-10 40.1 0.0 1e-09 38.6 0.0 1.7 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.31 ORY05833.1 - 6.8e-09 35.8 0.0 1.5e-08 34.7 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Pkinase PF00069.25 ORY05834.1 - 4.7e-69 232.7 0.0 6.1e-69 232.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY05834.1 - 4e-33 114.8 0.0 5.4e-33 114.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 ORY05834.1 - 2.7e-11 44.0 0.3 7.6e-11 42.5 0.3 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 ORY05834.1 - 1.4e-06 27.5 0.0 2.2e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 ORY05834.1 - 0.01 15.2 0.0 0.015 14.7 0.0 1.4 1 0 0 1 1 1 0 Kinase-like C2 PF00168.30 ORY05834.1 - 0.026 14.8 0.0 0.06 13.6 0.0 1.6 1 0 0 1 1 1 0 C2 domain FTA2 PF13095.6 ORY05834.1 - 0.12 11.9 0.1 0.85 9.2 0.0 2.0 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 PGI PF00342.19 ORY05835.1 - 3.4e-240 797.7 2.1 3.9e-240 797.5 2.1 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase Ribosomal_S21 PF01165.20 ORY05837.1 - 2.8e-13 49.4 0.9 4.1e-13 48.8 0.9 1.3 1 0 0 1 1 1 1 Ribosomal protein S21 PWI PF01480.17 ORY05838.1 - 1.7e-16 60.3 0.8 4.1e-16 59.1 0.8 1.7 1 0 0 1 1 1 1 PWI domain RRM_1 PF00076.22 ORY05838.1 - 0.031 14.1 0.0 0.36 10.7 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MR_MLE_C PF13378.6 ORY05839.1 - 1.3e-56 191.6 0.0 2.3e-56 190.8 0.0 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 ORY05839.1 - 1.5e-05 25.2 0.0 3.6e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MAAL_C PF07476.11 ORY05839.1 - 0.0071 15.5 0.0 0.012 14.7 0.0 1.4 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus AFG1_ATPase PF03969.16 ORY05840.1 - 1.1e-91 307.5 0.0 1.4e-86 290.6 0.0 2.2 2 0 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.6 ORY05840.1 - 0.0027 18.1 0.0 0.91 9.9 0.0 2.9 1 1 1 2 2 2 1 AAA ATPase domain AAA_14 PF13173.6 ORY05840.1 - 0.0028 17.7 0.0 0.0073 16.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 ORY05840.1 - 0.013 15.8 0.0 0.057 13.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain Bac_DnaA PF00308.18 ORY05840.1 - 0.072 12.9 0.3 10 5.9 0.2 2.8 2 1 0 2 2 2 0 Bacterial dnaA protein DUF5063 PF16702.5 ORY05840.1 - 0.072 13.5 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5063) TsaE PF02367.17 ORY05840.1 - 0.078 13.0 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 ORY05840.1 - 0.12 11.7 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PhoD PF09423.10 ORY05895.1 - 2.1e-115 385.5 2.9 2.6e-115 385.2 2.9 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase PhoD_N PF16655.5 ORY05895.1 - 3e-32 111.0 0.0 6.7e-32 109.9 0.0 1.6 1 0 0 1 1 1 1 PhoD-like phosphatase, N-terminal domain Pur_ac_phosph_N PF16656.5 ORY05895.1 - 0.00037 21.0 1.4 0.0014 19.2 0.4 2.5 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain ANAPC4 PF12896.7 ORY05896.1 - 7.2e-56 188.9 2.0 1e-55 188.4 2.0 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 ANAPC4_WD40 PF12894.7 ORY05896.1 - 2e-25 88.9 0.0 7.6e-23 80.6 0.0 3.0 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Mg_trans_NIPA PF05653.14 ORY05897.1 - 4.7e-99 331.2 16.0 5.6e-99 331.0 16.0 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 ORY05897.1 - 4.6e-05 23.6 8.1 4.6e-05 23.6 8.1 3.8 3 1 0 3 3 3 1 EamA-like transporter family Glyco_hydro_125 PF06824.11 ORY05899.1 - 4.8e-184 612.1 0.1 5.5e-184 611.9 0.1 1.0 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) DUF4964 PF16334.5 ORY05901.1 - 0.15 11.7 0.0 0.4 10.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4964) Ribosomal_L2_C PF03947.18 ORY05902.1 - 1e-40 138.8 3.7 1.8e-40 138.0 3.7 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 ORY05902.1 - 1e-13 51.0 0.1 2.6e-13 49.7 0.1 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain GRP PF07172.11 ORY05903.1 - 0.061 14.0 0.0 0.072 13.8 0.0 1.1 1 0 0 1 1 1 0 Glycine rich protein family DUF4188 PF13826.6 ORY05903.1 - 0.13 12.6 0.4 3.7 7.9 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4188) Consortin_C PF15281.6 ORY05903.1 - 0.95 9.5 3.0 1.8 8.6 2.9 1.6 1 1 0 1 1 1 0 Consortin C-terminus Zn_clus PF00172.18 ORY05904.1 - 1.3e-11 44.4 8.9 2.5e-11 43.5 8.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 ORY05904.1 - 7.2e-07 28.3 0.2 2.6e-06 26.5 0.0 1.8 1 1 1 2 2 2 1 Fungal specific transcription factor domain HutP PF09021.11 ORY05905.1 - 0.12 12.7 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 HutP Csm1_N PF18504.1 ORY05906.1 - 0.02 15.2 6.8 0.13 12.7 0.2 3.6 3 0 0 3 3 3 0 Csm1 N-terminal domain HC2 PF07382.11 ORY05906.1 - 0.023 14.8 7.5 0.049 13.7 7.5 1.4 1 0 0 1 1 1 0 Histone H1-like nucleoprotein HC2 HSP20 PF00011.21 ORY05908.1 - 1.7e-11 44.1 0.1 2.5e-11 43.6 0.1 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 ORY05908.1 - 0.0026 17.3 0.2 0.01 15.4 0.2 1.9 1 1 0 1 1 1 1 HSP20-like domain found in ArsA Saf_2TM PF18303.1 ORY05911.1 - 0.07 12.7 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain DUF3328 PF11807.8 ORY05912.1 - 2.5e-41 141.9 0.8 3.3e-41 141.5 0.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.8 ORY05913.1 - 2.2e-26 93.0 0.2 9.7e-25 87.6 0.2 2.0 2 0 0 2 2 2 2 Domain of unknown function (DUF3328) Spt20 PF12090.8 ORY05916.1 - 1.8e-38 132.5 0.1 1.8e-38 132.5 0.1 7.0 3 2 3 6 6 6 1 Spt20 family Fungal_trans PF04082.18 ORY05917.1 - 3.4e-12 46.0 0.5 6.4e-12 45.1 0.5 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY05917.1 - 1.7e-07 31.3 10.9 3.1e-07 30.4 10.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain bZIP_2 PF07716.15 ORY05917.1 - 0.84 9.8 6.4 1.8 8.7 6.4 1.5 1 0 0 1 1 1 0 Basic region leucine zipper Zn_clus PF00172.18 ORY05919.1 - 0.023 14.8 9.6 0.06 13.5 9.6 1.7 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain LSM PF01423.22 ORY05920.1 - 1.8e-18 66.0 0.1 2.2e-18 65.7 0.1 1.1 1 0 0 1 1 1 1 LSM domain DUF150_C PF17384.2 ORY05920.1 - 0.055 13.6 0.1 0.083 13.0 0.1 1.2 1 0 0 1 1 1 0 RimP C-terminal SH3 domain FoP_duplication PF13865.6 ORY05920.1 - 0.37 11.4 17.9 0.65 10.6 17.9 1.4 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 DUF4536 PF15055.6 ORY05921.1 - 0.18 12.1 12.5 5.2 7.4 0.0 5.8 7 0 0 7 7 7 0 Domain of unknown function (DUF4536) zf-C2H2 PF00096.26 ORY05924.1 - 4.5e-08 33.1 12.9 0.00085 19.7 3.6 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY05924.1 - 1.8e-05 25.2 9.0 0.009 16.8 1.5 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORY05924.1 - 0.00035 20.9 1.2 0.00035 20.9 1.2 2.9 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.8 ORY05924.1 - 0.00057 20.1 11.0 0.11 12.8 0.4 2.3 2 1 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ORY05924.1 - 0.057 13.8 7.1 1.6 9.3 2.3 2.6 2 1 0 2 2 2 0 Zinc-finger of C2H2 type SAD_SRA PF02182.17 ORY05925.1 - 2.8e-05 23.8 0.0 0.0001 22.0 0.0 1.8 1 1 0 1 1 1 1 SAD/SRA domain HET PF06985.11 ORY05926.1 - 7.3e-11 42.6 0.2 1.4e-06 28.7 0.0 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Hexapep PF00132.24 ORY05928.1 - 6e-06 25.8 2.2 0.084 12.6 0.1 3.2 1 1 2 3 3 3 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 ORY05928.1 - 0.00074 19.9 0.0 0.0016 18.8 0.0 1.6 1 0 0 1 1 1 1 MobA-like NTP transferase domain DUF4954 PF16314.5 ORY05928.1 - 0.0018 16.5 0.1 0.0031 15.7 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) NTP_transferase PF00483.23 ORY05928.1 - 0.023 14.3 0.0 0.051 13.1 0.0 1.5 2 0 0 2 2 2 0 Nucleotidyl transferase Fucokinase PF07959.12 ORY05928.1 - 0.18 10.7 0.1 0.26 10.2 0.1 1.1 1 0 0 1 1 1 0 L-fucokinase Hexapep_2 PF14602.6 ORY05928.1 - 2 8.3 5.7 4.6 7.1 2.2 3.0 1 1 1 2 2 2 0 Hexapeptide repeat of succinyl-transferase Ras PF00071.22 ORY05929.1 - 4.3e-32 110.9 0.0 6.5e-32 110.4 0.0 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY05929.1 - 4.2e-11 43.1 0.0 9.7e-11 41.9 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Helo_like_N PF17111.5 ORY05929.1 - 7e-05 22.3 0.5 7e-05 22.3 0.5 2.0 2 1 0 2 2 2 1 Fungal N-terminal domain of STAND proteins Arf PF00025.21 ORY05929.1 - 0.03 13.8 0.2 0.069 12.6 0.0 1.6 2 0 0 2 2 2 0 ADP-ribosylation factor family CCDC71L PF15374.6 ORY05929.1 - 0.12 11.6 2.2 0.22 10.8 2.2 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 71L SAT PF16073.5 ORY06003.1 - 1.2e-70 237.9 0.4 1.4e-70 237.8 0.4 1.0 1 0 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Zn_clus PF00172.18 ORY06005.1 - 4.6e-08 33.0 13.0 1e-07 31.9 13.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ORY06005.1 - 1e-07 31.3 0.7 3.6e-07 29.5 0.7 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 ORY06005.1 - 3.5e-05 24.0 13.5 0.00013 22.3 1.8 3.7 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY06005.1 - 0.00027 21.2 3.9 0.00027 21.2 3.9 4.4 3 1 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORY06005.1 - 0.006 17.3 1.0 0.006 17.3 1.0 4.1 3 1 0 3 3 3 2 C2H2-type zinc finger Cytochrom_CIII PF02085.16 ORY06005.1 - 2.3 8.6 7.5 0.94 9.9 4.8 1.7 2 0 0 2 2 2 0 Class III cytochrome C family PAT1 PF09770.9 ORY06005.1 - 3 6.0 7.3 4.8 5.3 7.3 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 adh_short_C2 PF13561.6 ORY06007.1 - 1.6e-57 194.8 2.9 2.4e-57 194.2 2.9 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY06007.1 - 8e-50 169.0 5.2 1e-49 168.7 5.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORY06007.1 - 8.3e-13 48.6 1.2 1.2e-12 48.2 1.2 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_2 PF03446.15 ORY06007.1 - 0.0028 17.8 0.5 0.0059 16.8 0.5 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase THF_DHG_CYH_C PF02882.19 ORY06007.1 - 0.0052 16.1 0.2 0.013 14.9 0.2 1.7 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Flu_M1_C PF08289.11 ORY06007.1 - 0.017 15.3 1.0 0.037 14.2 1.0 1.5 1 0 0 1 1 1 0 Influenza Matrix protein (M1) C-terminal domain DUF1372 PF07116.11 ORY06007.1 - 0.025 14.7 0.3 0.058 13.6 0.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1372) GlgS PF08971.11 ORY06007.1 - 0.16 12.0 0.1 5 7.2 0.0 2.4 2 0 0 2 2 2 0 Glycogen synthesis protein UPF0154 PF03672.13 ORY06008.1 - 0.013 15.5 1.2 0.052 13.6 0.5 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) ArgoL1 PF08699.10 ORY06008.1 - 0.038 13.7 0.0 0.12 12.1 0.0 1.9 1 1 0 1 1 1 0 Argonaute linker 1 domain TetR_C_18 PF17923.1 ORY06009.1 - 0.063 13.8 0.0 0.11 13.0 0.0 1.4 1 1 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain HET PF06985.11 ORY06010.1 - 8.9e-26 91.0 0.0 2.3e-25 89.7 0.0 1.8 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) AAA PF00004.29 ORY06010.1 - 0.00016 22.1 0.0 0.00045 20.6 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 ORY06010.1 - 0.0074 16.3 0.1 0.078 13.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Sigma54_activ_2 PF14532.6 ORY06010.1 - 0.0074 16.4 0.0 0.032 14.4 0.0 2.1 1 0 0 1 1 1 1 Sigma-54 interaction domain NACHT PF05729.12 ORY06010.1 - 0.022 14.7 0.1 0.064 13.2 0.1 1.7 1 1 0 1 1 1 0 NACHT domain ATPase_2 PF01637.18 ORY06010.1 - 0.048 13.6 0.0 0.089 12.7 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea ERAP1_C PF11838.8 ORY06010.1 - 0.048 13.2 0.1 0.09 12.3 0.1 1.4 1 0 0 1 1 1 0 ERAP1-like C-terminal domain AAA_19 PF13245.6 ORY06010.1 - 0.062 13.6 0.0 0.12 12.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain Pribosyltran_N PF13793.6 ORY06010.1 - 0.1 12.6 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of ribose phosphate pyrophosphokinase Peptidase_S41 PF03572.18 ORY06011.1 - 2.3e-07 30.6 0.0 6.8e-07 29.0 0.0 1.7 1 1 0 1 1 1 1 Peptidase family S41 BTB PF00651.31 ORY06012.1 - 0.033 14.4 0.0 0.041 14.1 0.0 1.2 1 0 0 1 1 1 0 BTB/POZ domain PKD_channel PF08016.12 ORY06013.1 - 0.35 9.5 7.9 1.6 7.3 0.8 2.2 2 0 0 2 2 2 0 Polycystin cation channel D-ser_dehydrat PF14031.6 ORY06015.1 - 1.8e-23 83.0 0.0 4.9e-23 81.6 0.0 1.8 1 0 0 1 1 1 1 Putative serine dehydratase domain Ala_racemase_N PF01168.20 ORY06015.1 - 1.2e-10 41.4 0.1 2.4e-10 40.4 0.1 1.4 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Bacillus_HBL PF05791.11 ORY06016.1 - 0.17 11.7 0.3 21 4.9 0.0 2.3 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) UBA2_C PF16195.5 ORY06016.1 - 0.45 11.2 4.7 0.68 10.7 1.4 2.5 2 0 0 2 2 2 0 SUMO-activating enzyme subunit 2 C-terminus Arfaptin PF06456.13 ORY06017.1 - 0.04 13.5 0.3 8.2 5.9 0.0 2.4 2 1 0 2 2 2 0 Arfaptin-like domain COG5 PF10392.9 ORY06017.1 - 0.089 13.0 0.1 0.23 11.6 0.1 1.6 1 0 0 1 1 1 0 Golgi transport complex subunit 5 Adeno_terminal PF02459.15 ORY06017.1 - 0.77 8.1 2.8 1.5 7.1 2.8 1.4 1 0 0 1 1 1 0 Adenoviral DNA terminal protein SPR1 PF15356.6 ORY06019.1 - 0.024 15.1 11.7 0.17 12.4 11.3 2.4 1 1 1 2 2 2 0 Psoriasis susceptibility locus 2 Miga PF10265.9 ORY06019.1 - 4.4 6.2 5.0 6.4 5.6 5.0 1.2 1 0 0 1 1 1 0 Mitoguardin Macoilin PF09726.9 ORY06019.1 - 8.8 4.7 9.4 14 4.1 9.4 1.2 1 0 0 1 1 1 0 Macoilin family FAD_binding_3 PF01494.19 ORY06020.1 - 6.4e-12 45.4 0.2 1.4e-11 44.3 0.2 1.5 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 ORY06020.1 - 0.019 15.2 0.0 0.045 14.0 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain LETM1 PF07766.13 ORY06021.1 - 3.9e-15 55.9 0.2 1.7e-08 34.1 0.0 2.2 2 0 0 2 2 2 2 LETM1-like protein RRM_1 PF00076.22 ORY06022.1 - 1e-08 34.9 0.0 2.1e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 ORY06022.1 - 0.014 15.0 0.0 0.032 13.8 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 ORY06022.1 - 0.027 14.6 0.0 0.054 13.6 0.0 1.5 1 0 0 1 1 1 0 Limkain b1 SET_assoc PF11767.8 ORY06022.1 - 0.22 11.2 0.0 0.42 10.3 0.0 1.4 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated RF-1 PF00472.20 ORY06023.1 - 3.3e-18 65.7 2.4 5.7e-18 65.0 2.4 1.4 1 0 0 1 1 1 1 RF-1 domain U3_assoc_6 PF08640.11 ORY06024.1 - 5.6e-24 84.0 1.0 3.1e-23 81.6 0.3 2.2 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.6 ORY06024.1 - 6e-08 32.9 8.1 0.15 13.0 0.0 5.1 4 1 2 6 6 6 3 Tetratricopeptide repeat NRDE-2 PF08424.10 ORY06024.1 - 0.011 14.8 0.1 0.049 12.8 0.1 2.1 3 0 0 3 3 3 0 NRDE-2, necessary for RNA interference Suf PF05843.14 ORY06024.1 - 0.14 12.2 0.5 5.6 6.9 0.0 2.6 3 0 0 3 3 3 0 Suppressor of forked protein (Suf) TPR_19 PF14559.6 ORY06024.1 - 0.17 12.4 8.8 32 5.1 5.5 3.8 4 1 0 4 4 4 0 Tetratricopeptide repeat Frag1 PF10277.9 ORY06025.1 - 1.2e-37 129.6 11.3 1.2e-37 129.6 11.3 3.0 3 1 0 3 3 3 1 Frag1/DRAM/Sfk1 family FtsX PF02687.21 ORY06025.1 - 1.4 9.4 8.9 25 5.4 0.0 4.1 3 1 0 3 3 3 0 FtsX-like permease family adh_short PF00106.25 ORY06027.1 - 1.1e-33 116.3 0.0 1.6e-33 115.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY06027.1 - 3.4e-28 98.8 0.0 4.9e-28 98.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY06027.1 - 2.4e-05 24.3 0.0 5.2e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 KR domain Glyco_hydro_10 PF00331.20 ORY06029.1 - 5.6e-90 301.7 0.6 8.6e-90 301.1 0.6 1.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_1 PF00734.18 ORY06029.1 - 5.4e-06 26.3 7.6 5.4e-06 26.3 7.6 2.4 3 0 0 3 3 3 1 Fungal cellulose binding domain Sugar_tr PF00083.24 ORY06031.1 - 2.2e-45 155.4 20.5 4.8e-45 154.3 20.5 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY06031.1 - 3.5e-17 62.4 25.1 3.5e-17 62.4 25.1 2.2 1 1 0 2 2 2 1 Major Facilitator Superfamily Ank_2 PF12796.7 ORY06032.1 - 1.1e-16 61.1 0.2 1.2e-11 45.1 0.0 2.0 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ORY06032.1 - 3.5e-16 59.1 4.2 1.1e-05 25.6 0.1 2.6 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY06032.1 - 2e-14 52.2 0.3 0.0017 18.7 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank PF00023.30 ORY06032.1 - 1.7e-13 50.4 0.8 8.9e-05 22.8 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 ORY06032.1 - 3.2e-13 49.9 0.3 2.4e-06 28.0 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) DUF3447 PF11929.8 ORY06032.1 - 0.14 12.1 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3447) Helo_like_N PF17111.5 ORY06033.1 - 0.071 12.5 0.2 1 8.7 0.0 2.3 1 1 2 3 3 3 0 Fungal N-terminal domain of STAND proteins Pkinase PF00069.25 ORY06035.1 - 1.6e-21 76.8 0.0 2.1e-21 76.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY06035.1 - 5.7e-11 42.2 0.0 1e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase DNA_ligase_A_M PF01068.21 ORY06036.1 - 2.6e-50 170.9 0.0 1.1e-47 162.4 0.0 2.3 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 ORY06036.1 - 6.7e-37 127.5 0.0 1.6e-36 126.2 0.0 1.7 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 ORY06036.1 - 2.6e-19 69.6 0.0 1.5e-18 67.2 0.0 2.4 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region mRNA_cap_enzyme PF01331.19 ORY06036.1 - 0.019 14.8 0.0 5.4 6.8 0.0 2.4 2 0 0 2 2 2 0 mRNA capping enzyme, catalytic domain IL32 PF15225.6 ORY06036.1 - 0.039 14.3 0.1 0.15 12.5 0.0 2.0 2 0 0 2 2 2 0 Interleukin 32 Ribosomal_S7e PF01251.18 ORY06037.1 - 0.018 14.8 0.6 0.027 14.2 0.6 1.2 1 0 0 1 1 1 0 Ribosomal protein S7e Bax1-I PF01027.20 ORY06037.1 - 0.026 14.4 3.8 0.036 13.9 3.8 1.1 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 DUF5316 PF17247.2 ORY06037.1 - 0.03 14.3 1.5 0.06 13.4 0.1 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5316) Utp11 PF03998.13 ORY06037.1 - 0.031 14.2 0.2 0.037 14.0 0.2 1.1 1 0 0 1 1 1 0 Utp11 protein CENP-H PF05837.12 ORY06037.1 - 0.059 13.8 3.1 0.094 13.1 3.1 1.2 1 0 0 1 1 1 0 Centromere protein H (CENP-H) DUF4956 PF16316.5 ORY06037.1 - 0.31 10.7 2.8 0.66 9.6 2.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4956) gag-asp_proteas PF13975.6 ORY06038.1 - 1.9e-07 31.6 0.0 0.0029 18.1 0.0 2.2 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 ORY06038.1 - 3.2e-07 30.9 0.2 0.034 14.8 0.1 2.2 2 0 0 2 2 2 2 Aspartyl protease Asp_protease PF09668.10 ORY06038.1 - 0.0033 17.2 0.0 0.027 14.2 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease CCDC53 PF10152.9 ORY06038.1 - 0.063 13.7 0.0 0.17 12.3 0.0 1.6 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex HET PF06985.11 ORY06039.1 - 2.2e-30 106.0 0.0 3.6e-30 105.2 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Alpha_L_fucos PF01120.17 ORY06039.1 - 0.1 12.0 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Alpha-L-fucosidase THUMP PF02926.17 ORY06040.1 - 4.8e-13 49.4 0.0 7.9e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 THUMP domain SAM_LFY PF01698.16 ORY06040.1 - 0.071 13.1 0.0 6.4 6.8 0.0 2.3 2 0 0 2 2 2 0 Floricaula / Leafy protein SAM domain APH PF01636.23 ORY06041.1 - 1.3e-09 38.3 0.0 2.4e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 ORY06041.1 - 0.014 14.7 0.0 0.11 11.7 0.0 2.0 2 0 0 2 2 2 0 Fructosamine kinase FAD_binding_7 PF03441.14 ORY06123.1 - 1.2e-72 243.6 0.3 1.8e-72 243.1 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 ORY06123.1 - 4.7e-37 127.5 0.0 9.1e-37 126.6 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase GFO_IDH_MocA PF01408.22 ORY06124.1 - 2.1e-09 38.3 0.0 4.5e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold ATPgrasp_N PF18130.1 ORY06125.1 - 2.4e-14 53.6 0.0 6.6e-14 52.2 0.0 1.8 1 0 0 1 1 1 1 ATP-grasp N-terminal domain ATP-grasp_4 PF13535.6 ORY06125.1 - 5.9e-10 39.0 0.0 1.7e-09 37.5 0.0 1.8 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 ORY06125.1 - 0.00046 20.3 0.0 0.024 14.7 0.0 2.5 2 0 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 ORY06125.1 - 0.00085 18.9 0.0 0.0018 17.9 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus CPSase_L_D2 PF02786.17 ORY06125.1 - 0.072 12.6 0.0 0.19 11.2 0.0 1.7 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, ATP binding domain GSH-S_ATP PF02955.16 ORY06125.1 - 0.074 12.5 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, ATP-grasp domain adh_short PF00106.25 ORY06126.1 - 7.4e-26 90.8 0.0 3.3e-21 75.6 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 ORY06126.1 - 3.7e-18 65.9 0.0 4.4e-13 49.3 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY06126.1 - 1.7e-06 28.1 0.0 2.2e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 KR domain ABC_membrane PF00664.23 ORY06127.1 - 1.6e-96 323.1 39.9 6.2e-52 176.9 17.5 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 ORY06127.1 - 2.2e-69 232.3 0.0 3.8e-33 114.9 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 ORY06127.1 - 8.4e-16 58.1 1.4 2.2e-05 24.0 0.0 4.2 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 ORY06127.1 - 1.4e-09 37.3 3.7 0.00012 21.0 0.1 2.6 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_15 PF13175.6 ORY06127.1 - 1e-06 28.7 0.0 0.0048 16.7 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_16 PF13191.6 ORY06127.1 - 1.2e-06 29.1 1.9 0.028 14.8 0.3 3.2 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 ORY06127.1 - 0.00018 21.8 2.3 0.11 12.7 0.1 3.7 2 2 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 ORY06127.1 - 0.0003 20.7 0.0 1.1 9.2 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 ORY06127.1 - 0.00039 20.1 0.3 1.3 8.9 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 ORY06127.1 - 0.00059 19.7 2.2 0.29 10.9 0.0 3.6 3 1 1 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 ORY06127.1 - 0.00064 19.3 1.3 0.048 13.2 0.0 3.6 4 0 0 4 4 4 1 AAA domain Zeta_toxin PF06414.12 ORY06127.1 - 0.0015 17.9 0.4 0.15 11.3 0.0 3.1 3 0 0 3 3 3 1 Zeta toxin AAA_5 PF07728.14 ORY06127.1 - 0.0025 17.8 0.8 2.9 7.9 0.0 3.8 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) SbcCD_C PF13558.6 ORY06127.1 - 0.0039 17.4 4.7 0.96 9.7 0.6 4.0 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 ORY06127.1 - 0.0087 16.6 0.1 2.8 8.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 ORY06127.1 - 0.024 15.2 0.0 2 9.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 ORY06127.1 - 0.027 14.1 0.4 5.2 6.6 0.1 3.3 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain G-alpha PF00503.20 ORY06127.1 - 0.05 12.8 0.0 3.3 6.8 0.0 2.3 2 0 0 2 2 2 0 G-protein alpha subunit AAA PF00004.29 ORY06127.1 - 0.052 14.0 8.2 4.2 7.8 0.6 4.1 2 2 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 ORY06127.1 - 0.066 12.9 4.3 3.5 7.3 0.0 3.7 4 0 0 4 4 4 0 AAA domain AAA_14 PF13173.6 ORY06127.1 - 0.073 13.1 1.0 1.3 9.1 0.0 3.5 5 0 0 5 5 4 0 AAA domain Dala_Dala_lig_N PF01820.21 ORY06127.1 - 0.094 13.2 0.0 6.1 7.4 0.0 2.7 2 0 0 2 2 2 0 D-ala D-ala ligase N-terminus APS_kinase PF01583.20 ORY06127.1 - 0.13 12.2 0.3 11 5.9 0.0 2.8 3 0 0 3 3 2 0 Adenylylsulphate kinase AAA_28 PF13521.6 ORY06127.1 - 0.2 11.9 1.2 0.55 10.5 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 ORY06127.1 - 0.2 11.8 0.9 9.7 6.3 0.0 3.1 3 0 0 3 3 3 0 AAA domain FA_desaturase PF00487.24 ORY06127.1 - 1.4 8.7 16.0 0.37 10.6 1.4 3.5 3 0 0 3 3 3 0 Fatty acid desaturase Methyltransf_25 PF13649.6 ORY06128.1 - 7.8e-07 29.7 0.0 2.5e-06 28.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY06128.1 - 1.6e-05 24.8 0.0 2.6e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY06128.1 - 0.00051 20.6 0.0 0.0013 19.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY06128.1 - 0.0053 16.6 0.0 0.023 14.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY06128.1 - 0.062 14.0 0.0 0.3 11.8 0.0 2.2 2 1 0 2 2 2 0 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 ORY06128.1 - 0.16 11.2 0.0 0.23 10.6 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family Clr5 PF14420.6 ORY06129.1 - 0.00052 20.2 0.0 0.00091 19.4 0.0 1.4 1 0 0 1 1 1 1 Clr5 domain Dynactin_p62 PF05502.13 ORY06130.1 - 4.8e-201 668.7 1.1 5.8e-201 668.4 1.1 1.0 1 0 0 1 1 1 1 Dynactin p62 family C1_4 PF07975.12 ORY06130.1 - 8.8 6.7 12.5 2.1 8.6 3.5 3.2 3 0 0 3 3 3 0 TFIIH C1-like domain Methyltransf_11 PF08241.12 ORY06131.1 - 6.6e-09 36.3 0.0 1.3e-08 35.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY06131.1 - 6.1e-08 32.7 0.0 9.7e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY06131.1 - 9e-07 29.5 0.0 2.1e-06 28.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY06131.1 - 2.8e-06 28.0 0.0 5.4e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY06131.1 - 0.00099 18.9 0.0 0.0017 18.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORY06131.1 - 0.0033 16.8 0.0 0.005 16.2 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CLU PF13236.6 ORY06134.1 - 2.9e-72 243.1 0.0 4.8e-72 242.4 0.0 1.4 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 ORY06134.1 - 1e-54 185.2 0.0 3.9e-54 183.3 0.0 2.1 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.6 ORY06134.1 - 4.5e-26 91.0 9.2 3.1e-12 46.6 0.1 4.6 2 1 3 5 5 5 4 Tetratricopeptide repeat CLU_N PF15044.6 ORY06134.1 - 9.3e-26 90.0 0.1 3.3e-25 88.3 0.1 2.0 1 0 0 1 1 1 1 Mitochondrial function, CLU-N-term TPR_10 PF13374.6 ORY06134.1 - 9.8e-24 82.5 9.5 1.2e-06 28.2 0.2 5.9 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 ORY06134.1 - 0.0011 18.9 6.6 6 7.2 0.1 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 ORY06134.1 - 0.0025 17.9 6.4 4.6 7.7 0.1 4.5 5 0 0 5 5 5 2 Tetratricopeptide repeat DUF727 PF05303.12 ORY06134.1 - 0.0039 17.2 0.0 0.012 15.6 0.0 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF727) TPR_17 PF13431.6 ORY06134.1 - 0.2 12.1 2.9 1.2e+02 3.4 0.2 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 ORY06134.1 - 0.32 11.1 1.4 14 5.9 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 ORY06134.1 - 0.39 10.6 3.4 10 6.1 0.6 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat RP-C_C PF11800.8 ORY06134.1 - 0.81 9.7 9.2 2.7 8.0 0.2 2.7 2 0 0 2 2 2 0 Replication protein C C-terminal region AAA_16 PF13191.6 ORY06135.1 - 1.8e-07 31.7 0.1 3.6e-07 30.7 0.1 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 ORY06135.1 - 0.0037 17.0 0.2 0.0083 15.8 0.2 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF815 PF05673.13 ORY06135.1 - 0.032 13.4 0.0 0.062 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 ORY06135.1 - 0.092 12.2 0.0 0.22 11.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_25 PF13481.6 ORY06135.1 - 0.12 11.9 0.1 0.7 9.4 0.1 2.3 1 1 0 1 1 1 0 AAA domain Terminase_6C PF17289.2 ORY06135.1 - 0.29 11.2 2.4 1 9.5 0.3 2.3 2 0 0 2 2 2 0 Terminase RNaseH-like domain But2 PF09792.9 ORY06136.1 - 9.3e-33 113.6 0.2 1.5e-32 112.9 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain MFS_1 PF07690.16 ORY06138.1 - 1.3e-34 119.7 33.9 4.9e-32 111.2 15.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 ORY06138.1 - 0.00051 18.5 0.0 0.0018 16.7 0.0 1.8 1 1 1 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family SirB PF04247.12 ORY06138.1 - 0.0054 16.8 0.9 0.025 14.7 0.9 2.1 1 0 0 1 1 1 1 Invasion gene expression up-regulator, SirB Sec39 PF08314.11 ORY06141.1 - 5.7e-255 848.4 0.1 6.6e-255 848.2 0.1 1.0 1 0 0 1 1 1 1 Secretory pathway protein Sec39 CopK PF11525.8 ORY06141.1 - 0.11 12.1 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 Copper resistance protein K NUDIX PF00293.28 ORY06142.1 - 0.00024 21.1 0.0 0.00039 20.5 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Ferric_reduct PF01794.19 ORY06143.1 - 2.3e-21 76.2 7.6 2.3e-21 76.2 7.6 2.2 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 ORY06143.1 - 5e-18 65.7 0.1 2.3e-15 57.0 0.1 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 ORY06143.1 - 6e-13 48.8 0.0 7e-11 42.2 0.0 2.4 1 1 0 1 1 1 1 FAD-binding domain DUF5391 PF17369.2 ORY06143.1 - 0.12 12.5 0.1 0.3 11.1 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5391) DUF3618 PF12277.8 ORY06145.1 - 0.11 12.7 4.3 2.8 8.3 0.5 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3618) Cwf_Cwc_15 PF04889.12 ORY06145.1 - 2 8.1 14.4 0.5 10.1 10.2 1.9 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Fun_ATP-synt_8 PF05933.13 ORY06146.1 - 1.4e-17 63.5 5.9 2e-17 63.1 5.9 1.2 1 0 0 1 1 1 1 Fungal ATP synthase protein 8 (A6L) Herpes_heli_pri PF05774.11 ORY06146.1 - 0.062 13.5 0.1 0.075 13.3 0.1 1.1 1 0 0 1 1 1 0 Herpesvirus helicase-primase complex component NmrA PF05368.13 ORY06147.1 - 3.6e-11 43.1 0.0 1.1e-10 41.5 0.0 1.9 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ORY06147.1 - 0.00018 21.5 0.0 0.00026 20.9 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding DUF4451 PF14616.6 ORY06148.1 - 1.2e-22 80.4 0.0 4e-22 78.7 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4451) PAPS_reduct PF01507.19 ORY06149.1 - 0.23 11.5 0.2 0.45 10.6 0.2 1.4 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family Peptidase_M41 PF01434.18 ORY06150.1 - 1.4e-68 230.6 0.2 2.8e-68 229.6 0.1 1.6 2 0 0 2 2 2 1 Peptidase family M41 AAA PF00004.29 ORY06150.1 - 9.7e-43 145.8 0.1 2.6e-42 144.4 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 ORY06150.1 - 1.5e-11 43.9 0.1 4.5e-11 42.4 0.1 1.9 1 0 0 1 1 1 1 AAA+ lid domain FtsH_ext PF06480.15 ORY06150.1 - 4.1e-11 43.2 0.0 1.1e-10 41.8 0.0 1.8 2 0 0 2 2 1 1 FtsH Extracellular AAA_5 PF07728.14 ORY06150.1 - 9.5e-05 22.4 0.1 0.00044 20.2 0.0 2.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 ORY06150.1 - 0.0032 17.9 0.2 0.27 11.6 0.2 2.8 1 1 0 2 2 2 1 AAA ATPase domain TIP49 PF06068.13 ORY06150.1 - 0.0056 15.9 0.0 0.01 15.1 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 ORY06150.1 - 0.0058 16.9 0.1 1.2 9.5 0.1 3.1 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 ORY06150.1 - 0.011 15.5 0.0 0.028 14.1 0.0 1.7 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 ORY06150.1 - 0.037 14.1 0.0 0.17 12.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) Binary_toxB_3 PF17476.2 ORY06150.1 - 0.043 14.0 0.4 0.17 12.1 0.1 2.1 2 0 0 2 2 2 0 Clostridial binary toxin B/anthrax toxin PA domain 3 AAA_17 PF13207.6 ORY06150.1 - 0.073 13.5 0.4 0.27 11.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain LysM PF01476.20 ORY06152.1 - 3.6e-06 26.9 0.0 6.3e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 LysM domain DUF903 PF06004.12 ORY06152.1 - 0.0081 16.0 0.3 0.017 15.0 0.3 1.5 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF903) Actino_peptide PF14408.6 ORY06152.1 - 0.011 15.8 1.3 0.16 12.1 0.3 2.5 1 1 1 2 2 2 0 Ribosomally synthesised peptide in actinomycetes UcrQ PF02939.16 ORY06153.1 - 9.3e-31 105.6 0.1 1.1e-30 105.4 0.1 1.1 1 0 0 1 1 1 1 UcrQ family Cyt_b-c1_8 PF10890.8 ORY06153.1 - 0.016 15.6 0.0 0.024 15.0 0.0 1.2 1 0 0 1 1 1 0 Cytochrome b-c1 complex subunit 8 CDH-cyt PF16010.5 ORY06157.1 - 4.8e-27 94.8 5.2 8.7e-27 94.0 5.2 1.3 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase Cytochrom_B561 PF03188.16 ORY06157.1 - 0.00019 21.6 12.6 0.00037 20.6 12.6 1.5 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF2427 PF10348.9 ORY06157.1 - 0.03 14.1 7.3 0.075 12.8 7.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF2427) Phage_holin_3_6 PF07332.11 ORY06157.1 - 7.5 6.6 9.7 63 3.7 5.9 2.8 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III DUF917 PF06032.12 ORY06158.1 - 2.8e-102 342.2 0.0 6.8e-102 340.9 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF917) Hydant_A_N PF05378.13 ORY06158.1 - 2.7e-28 98.9 3.9 6.9e-25 87.8 0.1 3.5 3 1 0 3 3 3 2 Hydantoinase/oxoprolinase N-terminal region Hydantoinase_A PF01968.18 ORY06158.1 - 1.1e-24 87.3 2.7 1.1e-21 77.4 0.1 3.2 2 1 1 3 3 3 3 Hydantoinase/oxoprolinase MutL PF13941.6 ORY06158.1 - 2.2e-05 23.2 0.7 0.0034 16.1 0.0 2.5 2 0 0 2 2 2 2 MutL protein FtsA PF14450.6 ORY06158.1 - 0.51 10.8 5.7 8.1 6.9 0.1 3.7 3 1 0 3 3 3 0 Cell division protein FtsA BcrAD_BadFG PF01869.20 ORY06158.1 - 3 7.2 7.7 1.1 8.7 0.1 2.9 2 1 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Acetyltransf_1 PF00583.25 ORY06211.1 - 2.1e-10 40.8 0.0 2.6e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ORY06211.1 - 5.2e-10 39.3 0.0 7.8e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ORY06211.1 - 5.5e-06 26.7 0.0 7.9e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ORY06211.1 - 0.03 14.3 0.0 0.074 13.0 0.0 1.7 1 1 0 1 1 1 0 FR47-like protein Acetyltransf_6 PF13480.7 ORY06211.1 - 0.054 13.6 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Antifungal_prot PF11402.8 ORY06211.1 - 0.092 13.0 0.1 0.18 12.1 0.1 1.4 1 0 0 1 1 1 0 Antifungal protein Nkap_C PF06047.11 ORY06211.1 - 0.21 11.8 0.9 0.35 11.0 0.9 1.4 1 0 0 1 1 1 0 NF-kappa-B-activating protein C-terminal domain SKG6 PF08693.10 ORY06214.1 - 0.00051 19.4 0.5 0.00092 18.6 0.5 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain VSP PF03302.13 ORY06214.1 - 0.0049 15.8 0.1 0.0049 15.8 0.1 1.7 2 0 0 2 2 2 1 Giardia variant-specific surface protein FAD_binding_4 PF01565.23 ORY06215.1 - 5.9e-18 65.0 0.0 9e-18 64.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 ORY06215.1 - 1.4e-05 25.1 0.0 3.1e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like DLH PF01738.18 ORY06216.1 - 4.7e-16 59.0 0.2 7.7e-13 48.5 0.1 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family FSH1 PF03959.13 ORY06216.1 - 0.067 12.8 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Glyco_hydro_92 PF07971.12 ORY06217.1 - 4.4e-21 75.3 0.0 5e-21 75.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 F-box-like PF12937.7 ORY06218.1 - 2.9e-06 27.1 0.1 8e-06 25.7 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY06218.1 - 0.0035 17.2 0.3 0.0097 15.8 0.3 1.8 1 0 0 1 1 1 1 F-box domain Pox_E8 PF03394.13 ORY06218.1 - 0.043 13.4 0.0 0.078 12.5 0.0 1.3 1 0 0 1 1 1 0 Poxvirus E8 protein NAD_binding_4 PF07993.12 ORY06220.1 - 9.3e-70 234.7 0.0 2e-69 233.7 0.0 1.6 2 0 0 2 2 2 1 Male sterility protein AMP-binding PF00501.28 ORY06220.1 - 3.1e-65 220.4 0.0 4.4e-65 219.9 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 ORY06220.1 - 3.1e-12 46.7 0.0 7.9e-12 45.4 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.21 ORY06220.1 - 5e-08 32.7 0.0 1e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family AMP-binding_C PF13193.6 ORY06220.1 - 2.9e-06 28.2 0.0 1.2e-05 26.2 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain 3Beta_HSD PF01073.19 ORY06220.1 - 0.0003 19.9 0.0 0.0005 19.2 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 ORY06220.1 - 0.0069 16.3 0.0 0.068 13.1 0.0 2.5 1 1 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 ORY06220.1 - 0.11 11.9 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase DUF2183 PF09949.9 ORY06221.1 - 1.7e-32 111.7 0.0 4.3e-32 110.4 0.0 1.8 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) LNS2 PF08235.13 ORY06221.1 - 0.11 12.0 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 LNS2 (Lipin/Ned1/Smp2) OAD_gamma PF04277.13 ORY06221.1 - 2.8 8.6 3.6 3.6 8.2 0.0 3.2 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain adh_short PF00106.25 ORY06222.1 - 2.6e-22 79.3 0.2 1.4e-15 57.3 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 ORY06222.1 - 1.3e-10 41.2 0.4 8.4e-07 28.8 0.0 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY06222.1 - 2.7e-05 24.1 0.1 4.3e-05 23.5 0.1 1.3 1 0 0 1 1 1 1 KR domain LSM PF01423.22 ORY06223.1 - 6.1e-12 45.1 0.0 8.8e-12 44.5 0.0 1.3 1 0 0 1 1 1 1 LSM domain HrpB2 PF09487.10 ORY06223.1 - 0.35 11.3 2.0 0.46 10.9 1.0 1.7 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB2) UPF0492 PF15744.5 ORY06224.1 - 0.098 11.9 2.3 0.14 11.3 2.1 1.2 1 1 0 1 1 1 0 Uncharacterized protein family UPF0492 GAS2 PF02187.17 ORY06226.1 - 4.7e-06 26.6 0.1 9.9e-06 25.6 0.1 1.5 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain HSBP1 PF06825.12 ORY06226.1 - 0.15 11.9 0.9 5 7.1 0.0 2.6 2 0 0 2 2 2 0 Heat shock factor binding protein 1 TFR_dimer PF04253.15 ORY06227.1 - 1.4e-20 73.6 0.0 2.3e-20 72.9 0.0 1.3 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 ORY06227.1 - 3.7e-20 72.5 0.0 6.1e-20 71.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 ORY06227.1 - 5.4e-09 36.0 0.1 2.2e-08 34.0 0.1 2.1 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 ORY06227.1 - 0.11 12.1 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 Pkinase PF00069.25 ORY06228.1 - 1.3e-05 24.8 0.0 1.8e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 ORY06228.1 - 0.0015 18.5 0.1 0.0039 17.1 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family p450 PF00067.22 ORY06229.1 - 1.3e-48 166.0 0.0 1.7e-48 165.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ank_2 PF12796.7 ORY06230.1 - 5.4e-52 174.3 0.3 3e-09 37.3 0.0 9.9 7 2 5 12 12 12 10 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY06230.1 - 8.1e-47 157.0 7.9 2.9e-09 37.3 0.1 11.6 12 1 1 13 13 11 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 ORY06230.1 - 1.2e-37 127.5 1.3 1.5e-06 28.3 0.0 12.0 11 2 2 13 13 13 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY06230.1 - 1.2e-32 108.2 3.8 0.0013 19.0 0.0 13.2 14 0 0 14 14 12 6 Ankyrin repeat Ank PF00023.30 ORY06230.1 - 2.9e-32 109.7 8.6 0.00078 19.8 0.0 12.3 13 0 0 13 13 11 6 Ankyrin repeat NACHT PF05729.12 ORY06230.1 - 2.9e-11 43.6 0.0 9.3e-11 41.9 0.0 2.0 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 ORY06230.1 - 9.6e-06 26.1 0.0 4.1e-05 24.0 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 ORY06230.1 - 3.9e-05 23.7 0.0 0.00011 22.2 0.0 1.7 2 0 0 2 2 1 1 ATPase domain predominantly from Archaea Goodbye PF17109.5 ORY06230.1 - 0.00014 22.2 0.0 0.00052 20.5 0.0 2.1 1 0 0 1 1 1 1 fungal STAND N-terminal Goodbye domain AAA_22 PF13401.6 ORY06230.1 - 0.00035 20.9 0.0 0.0019 18.5 0.0 2.3 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 ORY06230.1 - 0.0012 19.2 0.0 0.0037 17.7 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PIF1 PF05970.14 ORY06230.1 - 0.0038 16.4 0.0 0.058 12.6 0.0 2.2 2 0 0 2 2 2 1 PIF1-like helicase RNA_helicase PF00910.22 ORY06230.1 - 0.0047 17.3 0.0 0.011 16.1 0.0 1.7 1 0 0 1 1 1 1 RNA helicase NB-ARC PF00931.22 ORY06230.1 - 0.0066 15.7 0.0 0.017 14.3 0.0 1.7 1 1 0 1 1 1 1 NB-ARC domain AAA_PrkA PF08298.11 ORY06230.1 - 0.036 13.0 0.0 0.061 12.2 0.0 1.3 1 0 0 1 1 1 0 PrkA AAA domain AAA_24 PF13479.6 ORY06230.1 - 0.067 12.9 0.1 0.5 10.1 0.0 2.5 2 1 0 2 2 2 0 AAA domain AAA_14 PF13173.6 ORY06230.1 - 0.073 13.1 0.0 0.43 10.6 0.0 2.4 2 1 0 2 2 2 0 AAA domain Rad17 PF03215.15 ORY06230.1 - 0.077 12.9 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_33 PF13671.6 ORY06230.1 - 0.082 13.1 0.0 0.28 11.4 0.0 2.0 2 0 0 2 2 1 0 AAA domain AAA_11 PF13086.6 ORY06230.1 - 0.14 11.9 0.6 7.9 6.2 0.0 2.6 3 0 0 3 3 3 0 AAA domain zf-Di19 PF05605.12 ORY06231.1 - 0.11 12.8 2.2 0.24 11.7 2.2 1.6 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Presenilin PF01080.17 ORY06236.1 - 0.52 9.0 3.0 0.5 9.1 3.0 1.1 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 ORY06236.1 - 2.9 6.1 6.3 3.2 5.9 6.3 1.0 1 0 0 1 1 1 0 CDC45-like protein Coiled PF05710.12 ORY06236.1 - 4.4 8.2 8.0 0.49 11.3 2.9 1.9 2 0 0 2 2 2 0 Coiled coil DUF2470 PF10615.9 ORY06237.1 - 2.4e-21 76.2 0.2 4.1e-21 75.4 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) DUF4499 PF14934.6 ORY06237.1 - 0.1 13.0 1.8 0.16 12.3 1.5 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4499) Aminotran_3 PF00202.21 ORY06238.1 - 1e-110 370.2 0.0 1.3e-110 369.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 ORY06238.1 - 9.8e-07 28.3 0.0 2e-06 27.2 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II SNF2_N PF00176.23 ORY06239.1 - 1.4e-43 149.0 0.0 3.7e-43 147.6 0.0 1.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ORY06239.1 - 3.3e-05 24.2 0.0 8.6e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY06239.1 - 0.0054 16.7 0.0 0.68 9.9 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Stn1 PF10451.9 ORY06239.1 - 0.009 15.0 0.0 0.02 13.9 0.0 1.5 1 0 0 1 1 1 1 Telomere regulation protein Stn1 Synuclein PF01387.17 ORY06239.1 - 0.14 12.3 0.4 0.32 11.2 0.4 1.5 1 0 0 1 1 1 0 Synuclein HMG_box PF00505.19 ORY06240.1 - 2.1e-20 72.9 1.0 4.5e-20 71.8 1.0 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 ORY06240.1 - 1.5e-05 25.5 0.7 3.1e-05 24.5 0.7 1.5 1 0 0 1 1 1 1 HMG-box domain Abhydrolase_3 PF07859.13 ORY06242.1 - 2.2e-37 129.0 0.0 1.6e-25 90.2 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 ORY06242.1 - 0.21 10.4 0.0 0.3 9.9 0.0 1.2 1 0 0 1 1 1 0 Steryl acetyl hydrolase HET PF06985.11 ORY06244.1 - 1.2e-35 123.0 0.6 2.1e-35 122.2 0.6 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Aa_trans PF01490.18 ORY06246.1 - 5.2e-19 68.2 38.2 6.5e-19 67.9 38.2 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF3493 PF11998.8 ORY06246.1 - 0.043 14.0 2.3 1.2 9.4 0.1 2.8 2 0 0 2 2 2 0 Low psii accumulation1 / Rep27 BING4CT PF08149.11 ORY06247.1 - 5.5e-38 128.6 0.0 1.5e-34 117.7 0.0 3.0 3 0 0 3 3 3 2 BING4CT (NUC141) domain ANAPC4_WD40 PF12894.7 ORY06247.1 - 6.8e-06 26.3 0.0 7.1 7.0 0.0 5.4 2 1 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 ORY06247.1 - 1.5e-05 25.6 0.0 0.044 14.7 0.0 4.0 4 1 0 4 4 4 1 WD domain, G-beta repeat PQQ_2 PF13360.6 ORY06247.1 - 0.011 15.4 0.0 0.047 13.3 0.0 1.9 1 1 1 2 2 2 0 PQQ-like domain Coatomer_WDAD PF04053.14 ORY06247.1 - 0.023 13.7 0.1 0.051 12.6 0.0 1.5 2 0 0 2 2 2 0 Coatomer WD associated region Sulf_transp PF04143.14 ORY06250.1 - 1.2e-06 28.3 15.2 1.1e-05 25.1 4.5 3.0 3 1 0 3 3 3 2 Sulphur transport HET PF06985.11 ORY06362.1 - 1.3e-10 41.8 0.3 1.5e-10 41.6 0.3 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Nudix_hydro PF18290.1 ORY06362.1 - 0.065 13.2 0.0 0.092 12.7 0.0 1.2 1 0 0 1 1 1 0 Nudix hydrolase domain zf-C2H2 PF00096.26 ORY06364.1 - 0.086 13.3 0.6 0.086 13.3 0.6 2.9 3 0 0 3 3 3 0 Zinc finger, C2H2 type FMO-like PF00743.19 ORY06365.1 - 7.7e-27 93.9 0.0 7e-18 64.3 0.0 2.7 2 1 1 3 3 3 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 ORY06365.1 - 1e-06 28.2 0.1 3.3e-05 23.3 0.1 2.2 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ORY06365.1 - 0.01 15.0 0.0 0.01 15.0 0.0 1.9 3 0 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 ORY06365.1 - 0.046 12.9 0.0 0.46 9.7 0.0 2.5 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase ADH_zinc_N PF00107.26 ORY06367.1 - 0.0016 18.5 0.0 0.0034 17.4 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ORY06367.1 - 0.0028 17.5 0.0 0.0057 16.5 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Kinesin PF00225.23 ORY06368.1 - 3.3e-115 384.6 0.1 6.1e-115 383.7 0.1 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 ORY06368.1 - 8.6e-27 93.9 0.0 3e-26 92.2 0.0 1.9 1 0 0 1 1 1 1 Microtubule binding RRP36 PF06102.12 ORY06368.1 - 0.01 15.8 9.4 1.9 8.5 0.0 2.6 2 0 0 2 2 2 0 rRNA biogenesis protein RRP36 Herpes_UL14 PF03580.14 ORY06368.1 - 0.012 15.9 2.3 0.032 14.5 2.3 1.7 1 0 0 1 1 1 0 Herpesvirus UL14-like protein AAA_33 PF13671.6 ORY06368.1 - 0.26 11.4 3.0 0.28 11.3 0.1 2.6 3 1 0 3 3 3 0 AAA domain DUF4360 PF14273.6 ORY06369.1 - 6.6e-69 231.3 3.5 7.5e-69 231.2 3.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) PMSR PF01625.21 ORY06370.1 - 2.2e-64 216.3 0.5 2.6e-64 216.0 0.5 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase SH3_1 PF00018.28 ORY06370.1 - 8.1 6.1 7.6 1.5 8.5 1.0 2.3 1 1 1 2 2 2 0 SH3 domain GFA PF04828.14 ORY06371.1 - 5.2e-22 78.0 0.2 5.2e-22 78.0 0.2 1.5 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme zf-CSL PF05207.13 ORY06371.1 - 1.3 8.8 6.9 0.24 11.1 2.4 1.9 2 0 0 2 2 2 0 CSL zinc finger Amidase PF01425.21 ORY06372.1 - 3.2e-95 319.7 0.0 4.5e-95 319.3 0.0 1.2 1 0 0 1 1 1 1 Amidase UPF0180 PF03698.13 ORY06372.1 - 0.044 14.0 0.0 0.12 12.5 0.0 1.8 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0180) MARVEL PF01284.23 ORY06373.1 - 0.00057 19.9 9.9 0.00057 19.9 9.9 2.1 1 1 1 2 2 2 1 Membrane-associating domain TMEM190 PF15431.6 ORY06373.1 - 0.13 12.4 0.4 0.56 10.4 0.1 1.9 2 1 0 2 2 2 0 Transmembrane protein 190 MFS_1 PF07690.16 ORY06374.1 - 2.9e-13 49.5 18.5 2.9e-13 49.5 18.5 2.5 1 1 2 3 3 3 2 Major Facilitator Superfamily NUDIX PF00293.28 ORY06375.1 - 6.5e-06 26.2 0.0 2.2e-05 24.5 0.0 1.9 2 0 0 2 2 2 1 NUDIX domain IMPDH PF00478.25 ORY06376.1 - 1.8e-126 421.8 3.8 2.1e-126 421.6 3.8 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 ORY06376.1 - 2.6e-16 59.8 0.1 3.3e-07 30.6 0.0 2.4 2 0 0 2 2 2 2 CBS domain NMO PF03060.15 ORY06376.1 - 3.2e-07 30.0 0.3 0.0013 18.2 0.3 2.5 2 0 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.18 ORY06376.1 - 1.7e-06 27.4 0.4 4.6e-06 25.9 0.3 1.8 2 0 0 2 2 2 1 FMN-dependent dehydrogenase His_biosynth PF00977.21 ORY06376.1 - 0.00025 20.6 1.7 0.0018 17.7 1.7 2.2 1 1 0 1 1 1 1 Histidine biosynthesis protein NanE PF04131.14 ORY06376.1 - 0.0092 15.2 0.2 0.021 14.0 0.2 1.5 1 0 0 1 1 1 1 Putative N-acetylmannosamine-6-phosphate epimerase YpsA PF06908.11 ORY06376.1 - 0.017 15.2 0.0 0.03 14.3 0.0 1.3 1 0 0 1 1 1 0 YspA SLOG family ThiG PF05690.14 ORY06376.1 - 0.028 13.7 1.0 0.041 13.2 0.2 1.6 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG RasGAP PF00616.19 ORY06377.1 - 1.2e-52 178.7 0.0 3.9e-52 177.0 0.0 1.9 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 ORY06377.1 - 5.2e-49 165.9 2.7 2.5e-48 163.7 2.7 2.3 1 0 0 1 1 1 1 RasGAP C-terminus CH PF00307.31 ORY06377.1 - 1.7e-11 44.2 0.0 1.1e-10 41.7 0.0 2.3 2 0 0 2 2 2 1 Calponin homology (CH) domain IQ PF00612.27 ORY06377.1 - 6.1e-11 41.1 60.4 0.059 13.2 1.1 13.6 14 0 0 14 14 14 6 IQ calmodulin-binding motif Exo_endo_phos PF03372.23 ORY06378.1 - 1.3e-07 31.4 0.9 1.8e-07 30.9 0.9 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Epimerase PF01370.21 ORY06380.1 - 2.8e-06 27.0 0.1 9.2e-06 25.3 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 ORY06380.1 - 0.0028 17.6 0.0 0.0054 16.6 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 ORY06380.1 - 0.046 13.3 0.2 0.13 11.8 0.2 1.9 1 1 0 1 1 1 0 NmrA-like family adh_short PF00106.25 ORY06381.1 - 4.2e-28 98.1 0.0 5.5e-28 97.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY06381.1 - 1.4e-22 80.4 0.0 2e-22 79.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY06381.1 - 1.4e-08 34.9 0.1 5.6e-08 32.9 0.1 1.9 1 1 0 1 1 1 1 KR domain DUF948 PF06103.11 ORY06381.1 - 0.02 15.1 0.0 0.043 14.1 0.0 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) GPI-anchored PF10342.9 ORY06382.1 - 3e-21 76.0 0.2 3e-21 76.0 0.2 2.6 2 1 1 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family PI3K_1B_p101 PF10486.9 ORY06382.1 - 0.03 12.1 0.0 0.034 11.9 0.0 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Cellulase PF00150.18 ORY06383.1 - 1.6e-10 40.9 0.1 1.6e-10 40.9 0.1 1.9 2 1 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_42 PF02449.15 ORY06383.1 - 0.034 13.5 0.0 1.1 8.6 0.0 2.1 1 1 1 2 2 2 0 Beta-galactosidase TENA_THI-4 PF03070.16 ORY06384.1 - 1.3e-10 41.5 0.0 2.3e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 TENA/THI-4/PQQC family zf-BED PF02892.15 ORY06384.1 - 0.018 15.0 0.8 0.018 15.0 0.8 2.3 3 0 0 3 3 3 0 BED zinc finger p450 PF00067.22 ORY06385.1 - 6.8e-42 143.8 0.0 8.2e-42 143.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 RACo_C_ter PF14574.6 ORY06385.1 - 0.15 11.1 0.0 0.21 10.6 0.0 1.1 1 0 0 1 1 1 0 C-terminal domain of RACo the ASKHA domain Lactamase_B PF00753.27 ORY06386.1 - 2.6e-09 37.4 2.1 7e-09 36.0 1.1 2.1 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 ORY06386.1 - 0.0013 18.3 0.2 0.0025 17.3 0.2 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Colicin_Pyocin PF01320.18 ORY06386.1 - 0.1 12.7 0.2 0.28 11.3 0.2 1.8 1 0 0 1 1 1 0 Colicin immunity protein / pyocin immunity protein zf-RING_13 PF17977.1 ORY06388.1 - 0.04 14.1 0.1 0.21 11.7 0.1 2.2 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Podoplanin PF05808.11 ORY06391.1 - 0.0019 18.4 0.1 0.0045 17.1 0.1 1.5 1 1 0 1 1 1 1 Podoplanin PepSY_TM PF03929.16 ORY06391.1 - 0.014 15.1 0.3 0.031 13.9 0.3 1.7 1 1 0 1 1 1 0 PepSY-associated TM region SKG6 PF08693.10 ORY06391.1 - 0.023 14.1 1.3 0.023 14.1 1.3 2.0 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Nitrate_red_gam PF02665.14 ORY06391.1 - 0.12 11.9 0.0 0.22 11.0 0.0 1.4 2 0 0 2 2 2 0 Nitrate reductase gamma subunit Gram_pos_anchor PF00746.21 ORY06391.1 - 0.12 12.3 1.9 0.27 11.2 1.9 1.6 1 0 0 1 1 1 0 LPXTG cell wall anchor motif PD40 PF07676.12 ORY06394.1 - 0.013 15.4 1.0 10 6.2 0.1 3.6 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat LEF-9 PF05094.12 ORY06395.1 - 0.17 10.4 0.0 0.25 9.8 0.0 1.2 1 0 0 1 1 1 0 Late expression factor 9 (LEF-9) zf-C2H2_4 PF13894.6 ORY06397.1 - 2.9e-07 30.8 2.1 0.0053 17.5 0.1 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 ORY06397.1 - 0.00031 21.0 3.6 0.013 15.9 0.2 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type Ima1_N PF09779.9 ORY06397.1 - 0.0051 17.7 0.3 0.0089 16.9 0.3 1.4 1 0 0 1 1 1 1 Ima1 N-terminal domain Rad50_zn_hook PF04423.14 ORY06397.1 - 0.036 13.9 1.2 3.6 7.5 0.0 2.7 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-C2H2_2 PF12756.7 ORY06397.1 - 0.04 14.2 1.5 1.2 9.5 0.2 2.4 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 ORY06397.1 - 0.64 10.1 2.8 0.83 9.7 0.3 2.3 2 1 1 3 3 3 0 C2H2-type zinc finger Pex2_Pex12 PF04757.14 ORY06398.1 - 1.6e-36 126.0 3.5 2.3e-36 125.5 3.5 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.6 ORY06398.1 - 0.0017 18.5 4.2 0.0032 17.6 4.2 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 ORY06398.1 - 0.0048 16.9 1.3 0.016 15.2 1.3 1.9 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 ORY06398.1 - 0.062 13.2 0.6 0.13 12.1 0.6 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Na_trans_assoc PF06512.13 ORY06398.1 - 3.2 8.0 6.6 1.2 9.4 0.2 2.2 2 0 0 2 2 2 0 Sodium ion transport-associated zf-C3HC4_3 PF13920.6 ORY06398.1 - 3.3 7.7 8.9 2.9 7.8 5.2 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) IBN_N PF03810.19 ORY06399.1 - 2.4e-12 46.6 0.2 9.3e-11 41.5 0.1 3.0 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.12 ORY06399.1 - 0.0039 17.3 0.1 0.029 14.4 0.0 2.6 2 0 0 2 2 2 1 Exportin 1-like protein Cse1 PF08506.10 ORY06399.1 - 0.036 12.9 0.3 0.24 10.2 0.1 2.0 2 0 0 2 2 2 0 Cse1 adh_short PF00106.25 ORY06400.1 - 1.3e-23 83.5 1.8 1.8e-23 83.1 1.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY06400.1 - 8.5e-17 61.5 1.1 1.1e-16 61.1 1.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY06400.1 - 6.5e-13 49.0 1.0 9e-13 48.5 1.0 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 ORY06400.1 - 0.0011 18.1 0.1 0.0014 17.8 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 ORY06400.1 - 0.14 11.6 0.1 0.2 11.1 0.1 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 ORY06400.1 - 0.17 11.9 0.1 0.29 11.2 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Glyco_hydro_76 PF03663.14 ORY06401.1 - 8.5e-20 71.6 5.3 2e-10 40.7 0.1 3.6 4 0 0 4 4 4 3 Glycosyl hydrolase family 76 Peptidase_S28 PF05577.12 ORY06402.1 - 5.7e-49 167.1 0.1 1.5e-48 165.7 0.1 1.5 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_C12 PF01088.21 ORY06403.1 - 3.5e-54 183.8 0.0 4e-54 183.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Peptidase_S41 PF03572.18 ORY06404.1 - 1.1e-07 31.5 0.0 2.4e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase family S41 Atracotoxin PF05353.11 ORY06404.1 - 3 8.0 5.6 0.67 10.0 1.6 2.0 2 0 0 2 2 2 0 Delta Atracotoxin HET PF06985.11 ORY06406.1 - 3.7e-23 82.5 0.0 7.2e-23 81.6 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) CEBP1_N PF16368.5 ORY06406.1 - 0.079 12.5 0.1 0.12 11.8 0.1 1.2 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein 1 N-terminus GMC_oxred_N PF00732.19 ORY06407.1 - 3.3e-64 217.1 0.0 4.9e-64 216.6 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 ORY06407.1 - 7.8e-35 120.5 0.6 1.3e-34 119.7 0.6 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 ORY06407.1 - 7.8e-07 28.5 0.1 0.01 15.0 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 ORY06407.1 - 0.00025 20.8 1.1 0.1 12.2 0.0 2.7 2 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ORY06407.1 - 0.0089 16.2 0.0 0.022 14.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ORY06407.1 - 0.046 13.0 0.5 4.5 6.4 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 ORY06407.1 - 0.059 12.4 0.1 0.095 11.7 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein p450 PF00067.22 ORY06408.1 - 1.7e-52 178.7 0.0 2.4e-52 178.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Trp_DMAT PF11991.8 ORY06409.1 - 8.3e-17 61.6 0.0 9.8e-17 61.4 0.0 1.1 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase Fungal_trans PF04082.18 ORY06487.1 - 2.6e-21 75.9 0.4 5.3e-21 74.8 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY06487.1 - 2.1e-07 31.0 13.7 4.3e-07 29.9 13.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LIM PF00412.22 ORY06488.1 - 8.8e-24 83.5 30.9 2.4e-09 37.3 4.2 3.7 4 0 0 4 4 4 3 LIM domain SPT2 PF08243.11 ORY06488.1 - 0.85 10.2 6.3 2.1 8.9 6.3 1.6 1 0 0 1 1 1 0 SPT2 chromatin protein adh_short PF00106.25 ORY06489.1 - 2.3e-12 46.8 0.0 2.4e-09 36.9 0.0 2.4 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 ORY06489.1 - 0.00016 21.3 0.0 0.0018 17.8 0.0 2.1 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY06489.1 - 0.00019 21.4 0.0 0.0003 20.7 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ORY06489.1 - 0.002 17.6 0.0 0.0083 15.6 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family HMG_box_2 PF09011.10 ORY06490.1 - 1.1e-06 29.2 9.1 0.0034 17.9 0.7 3.5 3 0 0 3 3 3 2 HMG-box domain HMG_box PF00505.19 ORY06490.1 - 0.00029 21.2 6.2 0.0022 18.4 0.7 4.7 4 2 1 5 5 5 2 HMG (high mobility group) box DUF2462 PF09495.10 ORY06490.1 - 0.5 11.1 0.1 0.5 11.1 0.1 3.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2462) Aminotran_4 PF01063.19 ORY06491.1 - 5.4e-34 118.0 0.0 7.2e-34 117.6 0.0 1.2 1 0 0 1 1 1 1 Amino-transferase class IV Pkinase PF00069.25 ORY06492.1 - 5.7e-17 62.0 0.0 1.5e-16 60.6 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY06492.1 - 2.4e-07 30.3 0.0 1.7e-06 27.5 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Glyco_trans_4_5 PF16994.5 ORY06493.1 - 0.032 13.8 0.2 0.043 13.4 0.2 1.1 1 0 0 1 1 1 0 Glycosyl-transferase family 4 Aa_trans PF01490.18 ORY06494.1 - 2.2e-28 99.1 37.2 2.5e-28 98.9 37.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF4231 PF14015.6 ORY06494.1 - 5.5 7.5 12.3 0.74 10.3 1.0 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF4231) PEMT PF04191.13 ORY06495.1 - 9.9e-29 99.9 1.5 9.9e-29 99.9 1.5 1.5 2 0 0 2 2 2 1 Phospholipid methyltransferase DUF1056 PF06341.11 ORY06495.1 - 0.098 13.0 0.5 5.2 7.5 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1056) Tubulin PF00091.25 ORY06496.1 - 3.7e-68 229.6 0.0 9.2e-68 228.3 0.0 1.6 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 ORY06496.1 - 4.6e-43 146.4 0.1 7.6e-43 145.7 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 ORY06496.1 - 0.0001 22.6 0.0 0.00031 21.1 0.0 1.8 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 ORY06496.1 - 0.0015 17.8 0.0 0.024 13.8 0.0 2.1 2 0 0 2 2 2 1 Tubulin like Tubulin_3 PF14881.6 ORY06496.1 - 0.0037 17.0 0.0 0.0069 16.1 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Ceramidase PF05875.12 ORY06497.1 - 1e-108 362.8 9.0 1.2e-108 362.5 9.0 1.0 1 0 0 1 1 1 1 Ceramidase Peptidase_U4 PF03419.13 ORY06497.1 - 0.027 13.8 11.3 0.5 9.6 7.2 2.1 2 0 0 2 2 2 0 Sporulation factor SpoIIGA Vma12 PF11712.8 ORY06497.1 - 0.072 13.2 0.1 0.54 10.3 0.0 2.3 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase RFX1_trans_act PF04589.13 ORY06497.1 - 0.13 12.4 0.1 0.2 11.8 0.1 1.2 1 0 0 1 1 1 0 RFX1 transcription activation region DUF2070 PF09843.9 ORY06497.1 - 0.37 9.0 4.4 0.49 8.6 4.4 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF4131 PF13567.6 ORY06497.1 - 7 6.3 9.5 5.8 6.5 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) Prefoldin_2 PF01920.20 ORY06498.1 - 3.2e-17 62.4 2.8 4.4e-17 62.0 2.8 1.3 1 1 0 1 1 1 1 Prefoldin subunit RasGAP_C PF03836.15 ORY06498.1 - 0.012 15.8 3.6 0.19 11.8 0.6 2.1 2 0 0 2 2 2 0 RasGAP C-terminus SHE3 PF17078.5 ORY06498.1 - 0.016 14.9 1.6 0.15 11.8 0.1 1.9 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 Snf7 PF03357.21 ORY06498.1 - 0.059 13.0 4.8 1.1 8.8 0.1 2.1 2 0 0 2 2 2 0 Snf7 Emaravirus_P4 PF16505.5 ORY06498.1 - 0.071 12.1 0.1 0.076 12.0 0.1 1.1 1 0 0 1 1 1 0 P4 movement protein of Emaravirus, and the 30K superfamily DivIC PF04977.15 ORY06498.1 - 5.1 6.9 8.6 0.68 9.7 0.7 2.4 2 1 0 2 2 2 0 Septum formation initiator YabA PF06156.13 ORY06498.1 - 6.3 7.5 7.9 8.1 7.1 0.6 2.0 1 1 1 2 2 2 0 Initiation control protein YabA Sugar_tr PF00083.24 ORY06499.1 - 1.3e-45 156.1 23.8 1.8e-28 99.6 0.6 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 ORY06499.1 - 1.1e-06 27.9 36.5 0.00052 19.0 16.6 2.6 2 1 0 2 2 2 2 Major Facilitator Superfamily EpsG PF14897.6 ORY06499.1 - 3.4 6.9 17.6 0.011 15.0 5.3 2.2 2 1 1 3 3 3 0 EpsG family Epimerase PF01370.21 ORY06502.1 - 6.8e-14 51.9 0.2 6.3e-07 29.1 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NmrA PF05368.13 ORY06502.1 - 7.8e-06 25.6 0.1 1.2e-05 25.0 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ORY06502.1 - 2e-05 24.6 0.1 5.4e-05 23.2 0.2 1.8 2 0 0 2 2 2 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 ORY06502.1 - 0.00015 21.3 0.2 0.17 11.2 0.0 2.2 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase Semialdhyde_dh PF01118.24 ORY06502.1 - 0.0005 20.5 0.1 0.0066 16.9 0.0 2.4 2 1 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 ORY06502.1 - 0.00063 18.8 0.0 0.32 10.0 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family DXP_reductoisom PF02670.16 ORY06502.1 - 0.017 15.8 0.0 0.034 14.8 0.0 1.5 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase NAD_binding_4 PF07993.12 ORY06502.1 - 0.027 13.6 0.8 0.22 10.6 0.4 2.5 2 1 0 2 2 2 0 Male sterility protein Zn_clus PF00172.18 ORY06503.1 - 5.2e-08 32.9 7.8 1e-07 32.0 7.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 ORY06503.1 - 1.4e-06 27.4 2.7 2e-06 26.9 2.7 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain RTA1 PF04479.13 ORY06504.1 - 2.2e-74 249.5 11.4 2.2e-74 249.5 11.4 1.9 1 1 1 2 2 2 2 RTA1 like protein UNC45-central PF11701.8 ORY06505.1 - 6.4e-45 152.8 7.9 8.4e-45 152.5 4.9 2.8 4 0 0 4 4 4 1 Myosin-binding striated muscle assembly central TetR_C_28 PF17937.1 ORY06505.1 - 0.076 13.5 3.1 0.22 12.0 0.1 3.4 3 1 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain Atx10homo_assoc PF09759.9 ORY06505.1 - 0.099 12.7 0.1 20 5.3 0.0 3.4 3 0 0 3 3 3 0 Spinocerebellar ataxia type 10 protein domain Arm PF00514.23 ORY06505.1 - 0.19 11.8 12.0 16 5.7 0.4 6.4 6 1 1 7 7 7 0 Armadillo/beta-catenin-like repeat NopRA1 PF16201.5 ORY06505.1 - 1.7 8.2 5.0 25 4.4 0.1 3.4 3 1 1 4 4 4 0 Nucleolar pre-ribosomal-associated protein 1 LRR_4 PF12799.7 ORY06506.1 - 9.1e-18 64.1 44.7 0.00023 21.5 2.0 9.6 4 3 8 12 12 12 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY06506.1 - 1.9e-17 62.8 30.6 4.3e-06 26.4 0.1 6.3 5 1 1 6 6 6 6 Leucine rich repeat LRR_9 PF14580.6 ORY06506.1 - 1e-09 38.2 17.7 0.0059 16.1 1.5 4.4 1 1 2 4 4 4 4 Leucine-rich repeat LRR_6 PF13516.6 ORY06506.1 - 0.0012 18.8 29.9 1.5 9.1 0.1 9.9 11 0 0 11 11 11 3 Leucine Rich repeat LRR_1 PF00560.33 ORY06506.1 - 0.0014 18.9 22.9 9.3 7.2 0.3 9.6 8 2 0 8 8 8 2 Leucine Rich Repeat IPK PF03770.16 ORY06508.1 - 5.4e-55 186.3 0.0 1.1e-54 185.3 0.0 1.5 1 0 0 1 1 1 1 Inositol polyphosphate kinase Pkinase PF00069.25 ORY06509.1 - 3.2e-32 111.9 0.0 1.2e-19 70.7 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORY06509.1 - 7.8e-15 54.8 0.0 9.1e-09 35.0 0.0 2.5 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 ORY06509.1 - 0.0029 17.0 0.0 1.8 7.8 0.0 2.6 3 0 0 3 3 3 2 Kinase-like Kdo PF06293.14 ORY06509.1 - 0.15 11.4 0.0 0.28 10.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family AA_permease PF00324.21 ORY06511.1 - 4.1e-113 378.5 34.2 5e-113 378.2 34.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ORY06511.1 - 1.8e-22 79.8 36.6 2.4e-22 79.4 36.6 1.0 1 0 0 1 1 1 1 Amino acid permease Orthoreo_P10 PF07204.11 ORY06511.1 - 0.36 10.8 3.5 0.43 10.6 2.1 1.8 1 1 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 tRNA_int_end_N2 PF12928.7 ORY06512.1 - 1.5e-21 76.4 0.1 2.9e-21 75.4 0.1 1.5 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.14 ORY06512.1 - 0.071 12.8 0.1 0.36 10.5 0.0 2.1 2 0 0 2 2 2 0 tRNA intron endonuclease, N-terminal domain UQ_con PF00179.26 ORY06514.1 - 1.7e-40 137.9 0.0 2e-40 137.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 ORY06514.1 - 0.055 13.7 0.0 0.068 13.5 0.0 1.4 1 0 0 1 1 1 0 RWD domain Acetyltransf_1 PF00583.25 ORY06515.1 - 2.1e-08 34.4 0.0 2.9e-08 34.0 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ORY06515.1 - 4e-08 33.3 0.0 2.1e-07 30.9 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ORY06515.1 - 5.1e-08 33.2 0.0 7.5e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ORY06515.1 - 0.00023 21.0 0.0 0.0006 19.7 0.0 1.6 1 1 0 1 1 1 1 FR47-like protein RTP1_C1 PF10363.9 ORY06516.1 - 4.1e-22 78.5 0.0 7.8e-21 74.4 0.0 3.1 3 1 1 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 RTP1_C2 PF10304.9 ORY06516.1 - 3e-08 33.2 0.1 7.1e-08 32.0 0.1 1.7 1 0 0 1 1 1 1 Required for nuclear transport of RNA pol II C-terminus 2 WAPL PF07814.13 ORY06516.1 - 0.1 11.4 0.0 0.46 9.2 0.0 2.0 2 0 0 2 2 2 0 Wings apart-like protein regulation of heterochromatin LSM PF01423.22 ORY06517.1 - 1.3e-18 66.4 0.1 1.5e-18 66.3 0.1 1.0 1 0 0 1 1 1 1 LSM domain Adipokin_hormo PF06377.11 ORY06518.1 - 1.9e-05 24.9 27.7 11 6.5 0.5 9.1 8 2 1 9 9 9 3 Adipokinetic hormone DUF4340 PF14238.6 ORY06518.1 - 0.0022 18.1 1.0 13 5.7 0.4 4.2 1 1 2 3 3 3 1 Domain of unknown function (DUF4340) HNOBA PF07701.14 ORY06518.1 - 0.1 12.0 0.1 13 5.2 0.0 3.5 1 1 3 4 4 4 0 Heme NO binding associated I-set PF07679.16 ORY06518.1 - 0.72 10.0 23.8 43 4.3 0.1 7.9 3 1 4 7 7 7 0 Immunoglobulin I-set domain Apidaecin PF00807.17 ORY06518.1 - 1.6 8.9 7.9 12 6.1 0.1 3.2 2 0 0 2 2 2 0 Apidaecin PPR_2 PF13041.6 ORY06519.1 - 3.5e-06 27.1 0.0 0.046 13.9 0.0 3.6 3 0 0 3 3 3 2 PPR repeat family PPR_3 PF13812.6 ORY06519.1 - 2.5e-05 24.3 0.0 7.4 6.7 0.0 4.3 4 0 0 4 4 4 3 Pentatricopeptide repeat domain PPR PF01535.20 ORY06519.1 - 0.00087 19.4 0.3 5.3 7.5 0.1 3.8 3 0 0 3 3 3 2 PPR repeat PPR_long PF17177.4 ORY06519.1 - 0.065 12.6 0.0 0.24 10.7 0.0 1.9 2 0 0 2 2 2 0 Pentacotripeptide-repeat region of PRORP adh_short_C2 PF13561.6 ORY06520.1 - 1.3e-54 185.3 0.1 1.5e-54 185.0 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY06520.1 - 1.5e-43 148.5 0.1 1.9e-43 148.2 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORY06520.1 - 6e-08 32.8 0.0 1.3e-07 31.7 0.0 1.5 1 1 0 1 1 1 1 KR domain His_Phos_2 PF00328.22 ORY06521.1 - 3.3e-09 36.6 0.1 4.6e-06 26.2 0.0 2.2 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) Phage_Coat_B PF05356.11 ORY06521.1 - 0.15 11.9 0.6 1.2 9.1 0.4 2.3 2 0 0 2 2 2 0 Phage Coat protein B CoA_binding PF02629.19 ORY06522.1 - 1.8e-19 70.2 0.0 4e-19 69.1 0.0 1.6 1 0 0 1 1 1 1 CoA binding domain Citrate_synt PF00285.21 ORY06522.1 - 2.5e-19 69.6 0.0 4.6e-16 58.8 0.0 2.9 1 1 1 2 2 2 2 Citrate synthase, C-terminal domain Ligase_CoA PF00549.19 ORY06522.1 - 2.6e-13 50.0 0.2 4.3e-13 49.3 0.2 1.3 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 ORY06522.1 - 1.8e-06 27.8 0.1 1.2e-05 25.2 0.0 2.1 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain Citrate_bind PF16114.5 ORY06523.1 - 1e-87 292.2 0.0 1.4e-87 291.8 0.0 1.2 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding ATP-grasp_2 PF08442.10 ORY06523.1 - 6.9e-08 32.3 0.0 1.1e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain Sec61_beta PF03911.16 ORY06525.1 - 0.036 14.1 0.3 0.065 13.3 0.3 1.3 1 0 0 1 1 1 0 Sec61beta family GIY-YIG PF01541.24 ORY06525.1 - 0.13 12.6 0.2 0.28 11.5 0.2 1.5 1 0 0 1 1 1 0 GIY-YIG catalytic domain ORC6 PF05460.13 ORY06526.1 - 8.8e-38 130.5 14.0 3.7e-32 112.0 10.9 2.3 2 1 0 2 2 2 2 Origin recognition complex subunit 6 (ORC6) Nuc_N PF14448.6 ORY06526.1 - 0.072 12.9 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Nuclease N terminal Gemini_mov PF01708.16 ORY06526.1 - 1.8 8.4 3.4 2.3 8.0 0.0 2.4 2 1 0 2 2 2 0 Geminivirus putative movement protein Glyco_hydro_59 PF02057.15 ORY06527.1 - 4e-23 82.1 0.7 5.9e-23 81.5 0.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 Glyco_hydr_30_2 PF14587.6 ORY06527.1 - 1.2e-13 51.4 3.1 1.2e-10 41.5 0.1 2.3 2 0 0 2 2 2 2 O-Glycosyl hydrolase family 30 Glyco_hydro_30C PF17189.4 ORY06527.1 - 3.7e-12 46.3 2.0 1.3e-11 44.5 2.0 2.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain Glyco_hydro_30 PF02055.16 ORY06527.1 - 3.1e-10 39.5 0.1 5.2e-10 38.8 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain SET PF00856.28 ORY06529.1 - 1.4e-08 35.3 0.0 4.6e-08 33.6 0.0 1.9 1 1 0 1 1 1 1 SET domain KH_8 PF17903.1 ORY06530.1 - 8.9e-30 102.6 0.0 3.2e-29 100.8 0.0 2.0 2 0 0 2 2 2 1 Krr1 KH1 domain KH_1 PF00013.29 ORY06530.1 - 0.0021 17.8 2.4 0.31 10.9 0.0 3.4 3 0 0 3 3 3 2 KH domain Pfg27 PF09216.10 ORY06530.1 - 0.04 13.8 0.0 0.089 12.6 0.0 1.5 1 0 0 1 1 1 0 Pfg27 Kin17_mid PF10357.9 ORY06531.1 - 1.6e-44 150.9 0.2 1.6e-44 150.9 0.2 1.7 2 0 0 2 2 2 1 Domain of Kin17 curved DNA-binding protein zf-C2H2_2 PF12756.7 ORY06531.1 - 0.0013 19.0 3.5 0.0032 17.8 0.9 2.2 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 ORY06531.1 - 0.0018 18.6 5.4 0.0018 18.6 5.4 1.9 2 0 0 2 2 2 1 Zinc-finger of C2H2 type Paf1 PF03985.13 ORY06531.1 - 0.34 9.8 8.3 0.46 9.4 8.3 1.3 1 0 0 1 1 1 0 Paf1 zf-C2H2_jaz PF12171.8 ORY06531.1 - 0.45 10.9 7.6 0.17 12.2 4.7 1.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding CarbpepA_inh PF02977.15 ORY06531.1 - 1.6 8.6 4.4 1.3 8.8 2.4 1.8 2 0 0 2 2 2 0 Carboxypeptidase A inhibitor SYF2 PF08231.12 ORY06532.1 - 1.1e-39 136.3 18.7 1.1e-39 136.3 18.7 1.6 2 0 0 2 2 2 1 SYF2 splicing factor RRM_1 PF00076.22 ORY06533.1 - 0.00027 20.7 0.0 0.027 14.3 0.0 2.5 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Efg1 PF10153.9 ORY06533.1 - 5.5 7.4 15.5 1.8 8.9 9.4 2.2 2 0 0 2 2 2 0 rRNA-processing protein Efg1 CWC25 PF12542.8 ORY06534.1 - 7.9e-19 68.5 0.1 7.9e-19 68.5 0.1 3.7 3 1 1 4 4 4 1 Pre-mRNA splicing factor Cir_N PF10197.9 ORY06534.1 - 3.4e-13 49.5 12.6 3.4e-13 49.5 12.6 5.2 4 2 1 5 5 5 2 N-terminal domain of CBF1 interacting co-repressor CIR Rrf2 PF02082.20 ORY06634.1 - 0.1 13.0 0.1 0.24 11.8 0.1 1.6 1 0 0 1 1 1 0 Transcriptional regulator FOXP-CC PF16159.5 ORY06634.1 - 0.24 12.0 3.0 0.95 10.1 3.0 2.1 1 1 0 1 1 1 0 FOXP coiled-coil domain Ribosomal_L26 PF16906.5 ORY06635.1 - 1.6e-37 127.9 2.0 1.9e-37 127.6 2.0 1.1 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 ORY06635.1 - 9.3e-08 31.8 0.6 2.2e-07 30.6 0.6 1.7 1 0 0 1 1 1 1 KOW motif adh_short PF00106.25 ORY06636.1 - 1.6e-24 86.5 0.0 1.8e-24 86.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY06636.1 - 2.4e-20 73.1 0.0 3.2e-20 72.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY06636.1 - 7.3e-05 22.8 0.0 0.0001 22.3 0.0 1.2 1 0 0 1 1 1 1 KR domain HET PF06985.11 ORY06639.1 - 5.2e-25 88.5 0.0 9.2e-25 87.7 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF1843 PF08898.10 ORY06640.1 - 0.6 10.6 2.2 0.64 10.6 0.8 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) CK_II_beta PF01214.18 ORY06641.1 - 8.7e-76 253.8 0.0 1.9e-75 252.7 0.0 1.5 1 1 0 1 1 1 1 Casein kinase II regulatory subunit RRN3 PF05327.11 ORY06641.1 - 0.25 9.9 1.2 0.4 9.2 1.2 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Spt5_N PF11942.8 ORY06641.1 - 1.3 10.0 18.6 0.057 14.4 6.7 2.4 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal DUF4637 PF15470.6 ORY06641.1 - 4.5 7.0 8.4 0.23 11.2 2.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) PTPRCAP PF15713.5 ORY06641.1 - 8.4 6.7 9.8 37 4.6 5.1 2.2 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated Fungal_trans PF04082.18 ORY06642.1 - 1.3e-16 60.5 0.0 3e-16 59.2 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY06642.1 - 2.3e-08 34.0 8.7 3.9e-08 33.3 8.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LPP PF04728.13 ORY06642.1 - 0.063 13.7 0.5 0.13 12.6 0.5 1.5 1 0 0 1 1 1 0 Lipoprotein leucine-zipper HalX PF08663.10 ORY06642.1 - 0.067 13.5 0.1 0.14 12.5 0.1 1.5 1 0 0 1 1 1 0 HalX domain NPV_P10 PF05531.12 ORY06642.1 - 0.084 13.4 0.2 0.17 12.4 0.2 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein FMO-like PF00743.19 ORY06643.1 - 4.8e-09 35.2 0.6 2.6e-08 32.8 0.6 1.9 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 ORY06643.1 - 1.1e-08 35.1 0.0 4.4e-08 33.2 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 ORY06643.1 - 1.3e-07 31.2 0.2 0.0014 18.0 0.1 3.2 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ORY06643.1 - 4.7e-06 26.0 0.0 0.00041 19.6 0.0 2.5 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 ORY06643.1 - 0.00072 18.9 0.2 0.057 12.7 0.0 2.8 3 0 0 3 3 3 1 Thi4 family DAO PF01266.24 ORY06643.1 - 0.00077 19.1 0.4 0.16 11.5 0.3 3.3 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 ORY06643.1 - 0.045 13.7 0.1 0.38 10.7 0.0 2.6 3 0 0 3 3 3 0 FAD-NAD(P)-binding CoA_binding PF02629.19 ORY06643.1 - 0.079 13.6 0.0 0.69 10.6 0.0 2.4 2 0 0 2 2 2 0 CoA binding domain Pyr_redox PF00070.27 ORY06643.1 - 0.29 11.7 0.8 0.66 10.6 0.1 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ORY06643.1 - 0.29 10.3 1.1 5.5 6.1 1.2 2.8 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Tfb4 PF03850.14 ORY06644.1 - 9e-105 350.1 0.0 1.1e-104 349.9 0.0 1.0 1 0 0 1 1 1 1 Transcription factor Tfb4 zf-C2HC5 PF06221.13 ORY06644.1 - 0.77 9.8 6.2 1.4 9.0 6.2 1.4 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type Asparaginase_2 PF01112.18 ORY06645.1 - 2.2e-48 164.9 7.0 3e-32 111.9 0.4 2.5 2 0 0 2 2 2 2 Asparaginase Actin PF00022.19 ORY06646.1 - 5.4e-88 295.3 0.0 2.7e-53 181.1 0.0 2.0 1 1 1 2 2 2 2 Actin FtsA PF14450.6 ORY06646.1 - 0.00022 21.6 0.0 0.00044 20.6 0.0 1.5 1 1 0 1 1 1 1 Cell division protein FtsA MreB_Mbl PF06723.13 ORY06646.1 - 0.00032 19.6 0.0 0.055 12.3 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein TFIID_30kDa PF03540.13 ORY06647.1 - 5.1e-23 80.8 0.2 9.9e-23 79.9 0.2 1.5 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit Ribosomal_S19 PF00203.21 ORY06648.1 - 6.3e-27 93.3 0.0 7.7e-27 93.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 Mre11_DNA_bind PF04152.14 ORY06649.1 - 1.5e-52 178.3 0.8 1.5e-52 178.3 0.8 2.1 2 0 0 2 2 2 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 ORY06649.1 - 2.3e-15 57.6 2.7 3.9e-15 56.9 2.2 1.6 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 ORY06649.1 - 3.8e-08 33.7 0.1 5.6e-07 29.9 0.1 2.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Pkinase PF00069.25 ORY06652.1 - 3.7e-73 246.1 0.0 5.6e-73 245.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY06652.1 - 1.1e-30 106.8 0.0 3.1e-22 79.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 ORY06652.1 - 3.7e-06 26.5 0.1 0.51 9.6 0.0 3.1 3 0 0 3 3 3 3 Kinase-like Pkinase_fungal PF17667.1 ORY06652.1 - 0.012 14.4 0.0 0.023 13.5 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 ORY06652.1 - 0.013 14.9 0.0 0.022 14.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 ORY06652.1 - 0.029 14.3 0.0 0.46 10.4 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family DASH_Dad3 PF08656.10 ORY06653.1 - 1.1e-29 102.4 0.7 1.2e-29 102.1 0.7 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad3 Ribosomal_S5_C PF03719.15 ORY06654.1 - 6.9e-22 76.7 0.1 2.4e-21 75.0 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 ORY06654.1 - 6e-17 61.4 0.2 1.2e-16 60.5 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain zf-HC2 PF13490.6 ORY06654.1 - 0.13 12.5 0.1 0.35 11.2 0.1 1.7 1 0 0 1 1 1 0 Putative zinc-finger tRNA_U5-meth_tr PF05958.11 ORY06655.1 - 1.9e-10 40.3 0.0 1.1e-08 34.4 0.0 2.7 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_15 PF09445.10 ORY06655.1 - 0.00012 21.7 0.0 0.0002 21.0 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_25 PF13649.6 ORY06655.1 - 0.0014 19.2 0.0 0.0041 17.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 ORY06655.1 - 0.0018 17.7 0.0 0.0031 17.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 ORY06655.1 - 0.0032 17.3 0.0 0.0069 16.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY06655.1 - 0.048 14.3 0.0 0.19 12.4 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Sec3_C PF09763.9 ORY06655.1 - 0.11 10.9 0.4 0.16 10.3 0.4 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec3 Adaptin_N PF01602.20 ORY06656.1 - 1.3e-90 304.5 0.3 2.3e-90 303.6 0.3 1.3 1 0 0 1 1 1 1 Adaptin N terminal region Coatamer_beta_C PF07718.12 ORY06656.1 - 2.6e-58 195.9 0.6 6.2e-58 194.7 0.6 1.7 1 0 0 1 1 1 1 Coatomer beta C-terminal region Coatomer_b_Cpla PF14806.6 ORY06656.1 - 2.4e-57 192.4 0.0 6.2e-57 191.1 0.0 1.7 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Cnd1 PF12717.7 ORY06656.1 - 8.6e-12 45.4 1.2 1.3e-09 38.3 0.0 3.0 1 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 ORY06656.1 - 7.6e-09 35.9 4.6 0.00017 21.9 0.0 4.9 3 2 2 5 5 5 3 HEAT repeats Coatomer_g_Cpla PF16381.5 ORY06656.1 - 7.7e-05 22.8 0.1 0.00038 20.6 0.0 2.3 2 0 0 2 2 2 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT PF02985.22 ORY06656.1 - 0.0026 17.9 0.6 3.9 8.0 0.0 4.8 5 0 0 5 5 5 1 HEAT repeat AP4E_app_platf PF14807.6 ORY06656.1 - 0.047 14.1 0.2 0.13 12.6 0.2 1.8 1 0 0 1 1 1 0 Adaptin AP4 complex epsilon appendage platform Mago_nashi PF02792.14 ORY06657.1 - 8.8e-73 243.1 0.3 9.9e-73 242.9 0.3 1.0 1 0 0 1 1 1 1 Mago nashi protein Vac_ImportDeg PF09783.9 ORY06658.1 - 6.4e-68 227.6 1.4 7.9e-68 227.3 1.4 1.1 1 0 0 1 1 1 1 Vacuolar import and degradation protein Methyltransf_4 PF02390.17 ORY06659.1 - 3.7e-57 192.6 0.0 5.4e-57 192.0 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 ORY06659.1 - 0.00011 22.8 0.0 0.0003 21.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY06659.1 - 0.00015 22.5 0.0 0.00038 21.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY06659.1 - 0.0026 17.6 0.0 0.0037 17.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 ORY06659.1 - 0.0073 16.3 0.1 0.02 14.9 0.0 1.8 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 ORY06659.1 - 0.0082 15.7 0.0 0.017 14.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 ORY06659.1 - 0.021 15.5 0.0 0.11 13.2 0.0 2.3 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_18 PF12847.7 ORY06659.1 - 0.051 13.5 0.0 0.097 12.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Nop52 PF05997.12 ORY06660.1 - 6.6e-74 248.3 0.2 8.3e-74 248.0 0.2 1.1 1 0 0 1 1 1 1 Nucleolar protein,Nop52 TAN PF11640.8 ORY06660.1 - 0.0087 16.2 0.2 0.023 14.8 0.2 1.7 1 1 0 1 1 1 1 Telomere-length maintenance and DNA damage repair SET PF00856.28 ORY06661.1 - 1.2e-20 74.5 0.1 3.8e-20 72.9 0.1 1.9 1 1 0 1 1 1 1 SET domain Pre-SET PF05033.16 ORY06661.1 - 1.1e-13 51.8 6.2 1.1e-13 51.8 6.2 2.3 2 0 0 2 2 2 1 Pre-SET motif Chromo PF00385.24 ORY06661.1 - 0.1 12.6 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain La PF05383.17 ORY06664.1 - 1.5e-19 69.8 0.2 2.5e-19 69.1 0.2 1.3 1 0 0 1 1 1 1 La domain HisKA PF00512.25 ORY06666.1 - 0.1 12.6 0.1 1.7 8.7 0.0 2.4 2 0 0 2 2 2 0 His Kinase A (phospho-acceptor) domain MFS_1 PF07690.16 ORY06667.1 - 5.4e-22 78.2 57.7 2.6e-13 49.7 25.3 2.6 2 1 1 3 3 3 2 Major Facilitator Superfamily MFS_2 PF13347.6 ORY06667.1 - 8.4e-05 21.3 13.6 8.4e-05 21.3 13.6 2.6 1 1 1 2 2 2 2 MFS/sugar transport protein DAGK_cat PF00781.24 ORY06670.1 - 2.9e-26 91.5 0.1 4.6e-26 90.9 0.1 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain SET PF00856.28 ORY06671.1 - 3.2e-12 47.1 0.7 1.2e-11 45.3 0.2 2.3 2 1 0 2 2 2 1 SET domain Abhydrolase_1 PF00561.20 ORY06672.1 - 7.9e-24 84.7 0.1 9.8e-24 84.4 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORY06672.1 - 4.5e-20 73.2 1.8 5.1e-20 73.0 1.8 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORY06672.1 - 9.4e-17 61.1 0.0 1.1e-16 60.8 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 ORY06672.1 - 3.7e-05 22.6 0.0 5.4e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Ndr family Abhydrolase_3 PF07859.13 ORY06672.1 - 0.0017 18.3 0.0 0.0021 18.0 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Ser_hydrolase PF06821.13 ORY06672.1 - 0.0032 17.3 0.9 0.005 16.7 0.9 1.4 1 1 0 1 1 1 1 Serine hydrolase LIDHydrolase PF10230.9 ORY06672.1 - 0.0046 16.5 0.0 0.0056 16.3 0.0 1.2 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase PGAP1 PF07819.13 ORY06672.1 - 0.0062 16.3 0.7 0.0095 15.7 0.7 1.2 1 0 0 1 1 1 1 PGAP1-like protein Esterase_phd PF10503.9 ORY06672.1 - 0.027 14.0 0.1 0.051 13.0 0.1 1.4 1 0 0 1 1 1 0 Esterase PHB depolymerase LCAT PF02450.15 ORY06672.1 - 0.049 12.8 0.0 0.065 12.4 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Thioesterase PF00975.20 ORY06672.1 - 0.053 13.6 0.0 0.07 13.2 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Esterase PF00756.20 ORY06672.1 - 0.12 12.1 0.1 0.24 11.0 0.0 1.5 2 0 0 2 2 2 0 Putative esterase Peptidase_S9 PF00326.21 ORY06672.1 - 0.22 11.0 0.0 0.48 9.8 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family AdoHcyase PF05221.17 ORY06673.1 - 2.1e-127 424.4 0.0 1.1e-73 248.0 0.1 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 ORY06673.1 - 7.8e-84 279.6 2.6 1.2e-83 279.1 2.6 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 ORY06673.1 - 6.1e-08 32.2 0.1 1.5e-07 31.0 0.1 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 ORY06673.1 - 0.00042 19.9 0.4 0.00074 19.1 0.4 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain ELFV_dehydrog PF00208.21 ORY06673.1 - 0.00083 19.2 0.4 0.0016 18.2 0.3 1.6 1 1 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase TrkA_N PF02254.18 ORY06673.1 - 0.0075 16.5 0.1 0.019 15.2 0.1 1.7 1 0 0 1 1 1 1 TrkA-N domain 3HCDH_N PF02737.18 ORY06673.1 - 0.054 13.4 0.3 0.093 12.6 0.3 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain p450 PF00067.22 ORY06674.1 - 1e-27 97.0 0.1 1.2e-25 90.2 0.0 2.8 2 1 1 3 3 3 2 Cytochrome P450 GMC_oxred_N PF00732.19 ORY06675.1 - 1.7e-51 175.4 0.0 2.2e-51 175.0 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 ORY06675.1 - 3.7e-31 108.6 0.0 6.3e-31 107.8 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 ORY06675.1 - 1.8e-05 24.0 0.2 0.0062 15.7 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 ORY06675.1 - 0.00016 21.4 0.0 0.0069 16.0 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ORY06675.1 - 0.00017 21.7 0.1 0.00037 20.7 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ORY06675.1 - 0.00044 19.6 0.0 0.0037 16.5 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 ORY06675.1 - 0.00056 19.1 0.0 0.00086 18.5 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 ORY06675.1 - 0.029 13.6 0.0 0.047 12.9 0.0 1.2 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.6 ORY06675.1 - 0.11 11.7 0.0 0.32 10.2 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ORY06675.1 - 0.17 10.5 0.0 0.32 9.7 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein DUF4029 PF13221.6 ORY06676.1 - 0.098 13.3 1.5 1.9 9.2 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4029) DUF4231 PF14015.6 ORY06676.1 - 3.5 8.2 6.7 4.6 7.8 0.9 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) FAD_binding_4 PF01565.23 ORY06677.1 - 2.2e-20 72.8 2.0 4.1e-20 71.9 2.0 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 ORY06677.1 - 0.0045 17.0 0.4 0.022 14.9 0.0 2.3 2 0 0 2 2 2 1 Berberine and berberine like adh_short PF00106.25 ORY06678.1 - 2.1e-19 69.8 0.0 6e-15 55.2 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 ORY06678.1 - 1.1e-06 28.3 0.0 3.4e-06 26.8 0.0 1.8 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY06678.1 - 2e-05 24.6 0.0 2.9e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ORY06678.1 - 0.026 14.0 0.0 0.045 13.2 0.0 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Pkinase PF00069.25 ORY06680.1 - 2e-12 47.1 0.0 4.2e-11 42.7 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Ank_2 PF12796.7 ORY06680.1 - 6.1e-10 39.5 0.0 5.4e-06 26.9 0.0 3.2 3 1 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ORY06680.1 - 8.7e-08 31.9 0.0 0.46 11.2 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 ORY06680.1 - 2e-06 28.0 0.0 0.034 14.6 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat Pkinase_Tyr PF07714.17 ORY06680.1 - 6.5e-05 22.3 0.0 0.00023 20.5 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Ank_4 PF13637.6 ORY06680.1 - 0.0003 21.3 0.2 21 5.9 0.0 4.3 2 1 3 5 5 5 2 Ankyrin repeats (many copies) Pox_ser-thr_kin PF05445.11 ORY06680.1 - 0.00072 18.6 0.0 0.0011 18.0 0.0 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Asp_protease_2 PF13650.6 ORY06748.1 - 0.048 14.3 0.0 1.4 9.6 0.0 2.6 2 0 0 2 2 2 0 Aspartyl protease Haem_degrading PF03928.14 ORY06749.1 - 2.4e-35 121.2 0.0 2.9e-35 120.9 0.0 1.1 1 0 0 1 1 1 1 Haem-degrading Pkinase PF00069.25 ORY06752.1 - 9.2e-06 25.2 0.0 1e-05 25.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY06752.1 - 0.18 11.1 0.1 0.21 10.9 0.1 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase Pkinase PF00069.25 ORY06753.1 - 2.4e-06 27.1 0.0 3e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY06753.1 - 0.021 14.1 0.0 0.031 13.5 0.0 1.4 1 1 0 1 1 1 0 Protein tyrosine kinase ERp29_N PF07912.13 ORY06753.1 - 0.081 13.1 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 ERp29, N-terminal domain Pkinase PF00069.25 ORY06754.1 - 6.6e-11 42.1 0.0 8.4e-11 41.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY06754.1 - 4.1e-05 23.0 0.1 0.00015 21.2 0.1 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 ORY06754.1 - 0.021 14.2 0.9 0.031 13.6 0.9 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 ORY06754.1 - 0.12 11.7 0.0 0.16 11.2 0.0 1.1 1 0 0 1 1 1 0 Kinase-like Tfb5 PF06331.12 ORY06754.1 - 0.16 12.0 0.2 0.39 10.7 0.2 1.6 1 0 0 1 1 1 0 Transcription factor TFIIH complex subunit Tfb5 Astacin PF01400.24 ORY06756.1 - 0.0016 18.1 2.3 0.0077 15.9 1.8 1.9 1 1 1 2 2 2 1 Astacin (Peptidase family M12A) Reprolysin_4 PF13583.6 ORY06756.1 - 0.071 12.8 0.0 0.097 12.3 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 ORY06756.1 - 0.12 12.2 0.7 0.21 11.4 0.7 1.3 1 0 0 1 1 1 0 Matrixin Reprolysin_5 PF13688.6 ORY06756.1 - 0.16 12.1 0.2 0.23 11.6 0.2 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12 RhoGEF PF00621.20 ORY06757.1 - 2.2e-07 31.3 0.0 4.8e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 RhoGEF domain Helo_like_N PF17111.5 ORY06757.1 - 0.00017 21.0 1.6 0.00017 21.0 1.6 1.7 2 0 0 2 2 2 1 Fungal N-terminal domain of STAND proteins Caskin-Pro-rich PF16907.5 ORY06757.1 - 0.46 11.0 6.5 1.9 9.0 0.6 2.7 2 0 0 2 2 2 0 Proline rich region of Caskin proteins MRP-S26 PF14943.6 ORY06758.1 - 0.034 14.0 0.4 0.051 13.5 0.4 1.2 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 Pkinase PF00069.25 ORY06760.1 - 1.6e-20 73.6 0.0 1.6e-19 70.3 0.0 2.5 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY06760.1 - 8.7e-09 35.0 0.0 2.8e-08 33.3 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY06760.1 - 0.017 14.5 0.0 0.032 13.5 0.0 1.4 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 ORY06760.1 - 0.063 13.2 0.1 0.13 12.1 0.1 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family AA_permease_2 PF13520.6 ORY06761.1 - 6.9e-60 203.1 32.8 9.1e-60 202.7 32.8 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ORY06761.1 - 1.9e-10 39.9 25.6 2.5e-10 39.6 25.6 1.1 1 0 0 1 1 1 1 Amino acid permease DUF929 PF06053.11 ORY06761.1 - 0.071 12.4 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF929) CorA PF01544.18 ORY06762.1 - 0.013 14.8 4.2 0.037 13.3 4.2 1.9 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein Pkinase PF00069.25 ORY06763.1 - 2.9e-22 79.3 0.1 1.8e-17 63.6 0.0 3.1 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORY06763.1 - 7.9e-09 35.2 0.0 4.9e-07 29.3 0.0 2.8 2 1 0 2 2 2 1 Protein tyrosine kinase CorA PF01544.18 ORY06764.1 - 0.0091 15.3 16.4 0.23 10.7 16.4 2.2 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein PIG-Y PF15159.6 ORY06764.1 - 2.2 9.3 7.2 5 8.1 7.2 1.5 1 0 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y DLH PF01738.18 ORY06766.1 - 8.3e-23 81.1 0.0 1e-22 80.8 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 ORY06766.1 - 0.0065 16.1 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold zf-RING_2 PF13639.6 ORY06767.1 - 8.2e-10 38.9 6.5 1.5e-09 38.0 6.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 ORY06767.1 - 1.2e-08 34.8 2.6 4.1e-08 33.1 2.7 1.9 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 ORY06767.1 - 8.5e-07 28.8 4.8 1.5e-06 27.9 4.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 ORY06767.1 - 6e-06 26.0 4.4 1.2e-05 25.0 4.4 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 ORY06767.1 - 2e-05 24.2 1.1 3.7e-05 23.4 1.1 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 ORY06767.1 - 2.2e-05 24.7 5.1 5.1e-05 23.5 5.1 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 ORY06767.1 - 2.5e-05 24.2 5.7 4.4e-05 23.3 5.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 ORY06767.1 - 4.7e-05 23.2 3.9 8.5e-05 22.3 3.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 ORY06767.1 - 0.0001 22.1 4.6 0.00019 21.2 4.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF1272 PF06906.11 ORY06767.1 - 0.017 15.2 3.7 0.017 15.2 3.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) zf-UDP PF14569.6 ORY06767.1 - 0.02 15.0 0.6 0.04 14.0 0.6 1.5 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-ANAPC11 PF12861.7 ORY06767.1 - 0.028 14.5 5.6 0.045 13.8 3.5 2.3 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 ORY06767.1 - 0.053 13.3 3.0 0.13 12.1 3.0 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Rtf2 PF04641.12 ORY06767.1 - 0.064 12.6 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Rtf2 RING-finger zf-Nse PF11789.8 ORY06767.1 - 0.12 12.2 1.0 0.21 11.4 1.0 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.6 ORY06767.1 - 0.21 11.8 4.3 0.53 10.5 4.3 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING FYVE PF01363.21 ORY06767.1 - 5 7.3 8.2 1.3 9.3 3.6 2.1 2 1 0 2 2 2 0 FYVE zinc finger Cast PF10174.9 ORY06768.1 - 0.0012 17.2 8.2 0.0014 17.0 8.2 1.2 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone AAA_13 PF13166.6 ORY06768.1 - 0.0076 15.0 6.1 0.01 14.6 6.1 1.0 1 0 0 1 1 1 1 AAA domain TMF_DNA_bd PF12329.8 ORY06768.1 - 0.0078 16.2 6.8 0.0078 16.2 6.8 2.4 1 1 2 3 3 3 1 TATA element modulatory factor 1 DNA binding DP-EP PF08985.11 ORY06768.1 - 0.075 13.2 0.1 0.11 12.7 0.1 1.2 1 0 0 1 1 1 0 DP-EP family Fusion_F0 PF13044.6 ORY06768.1 - 0.1 11.3 0.0 0.14 10.8 0.0 1.1 1 0 0 1 1 1 0 Fusion glycoprotein F0, Isavirus Peptidase_M26_C PF07580.14 ORY06768.1 - 0.17 10.3 5.8 0.23 9.9 5.8 1.0 1 0 0 1 1 1 0 M26 IgA1-specific Metallo-endopeptidase C-terminal region Cep57_CLD_2 PF14197.6 ORY06768.1 - 0.93 9.6 7.8 0.86 9.7 5.0 2.1 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 USP8_interact PF08941.10 ORY06768.1 - 1.2 8.9 9.0 4.2 7.1 3.0 2.2 1 1 1 2 2 2 0 USP8 interacting UPF0242 PF06785.11 ORY06768.1 - 3.7 7.6 14.4 8.3 6.5 14.4 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Atg14 PF10186.9 ORY06768.1 - 7.6 5.5 13.0 1.8 7.6 1.9 2.0 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Acetyltransf_1 PF00583.25 ORY06770.1 - 2.2e-08 34.3 0.0 3.5e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ORY06770.1 - 1.7e-06 28.0 0.0 2.8e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ORY06770.1 - 2e-05 24.9 0.0 2.8e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF1428 PF07237.11 ORY06770.1 - 0.14 12.4 0.0 0.22 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1428) HR1 PF02185.16 ORY06771.1 - 0.05 13.7 0.3 0.21 11.7 0.0 2.2 2 0 0 2 2 2 0 Hr1 repeat Ank_2 PF12796.7 ORY06772.1 - 2.8e-15 56.7 0.0 3.4e-10 40.4 0.0 2.5 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ORY06772.1 - 2e-10 40.0 0.5 0.00051 20.3 0.0 4.7 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 ORY06772.1 - 3.1e-10 40.1 0.3 0.0029 17.9 0.0 3.7 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 ORY06772.1 - 2.1e-09 37.7 0.3 0.00015 22.2 0.0 3.7 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 ORY06772.1 - 0.00077 19.8 3.0 0.22 12.0 0.1 3.7 3 1 0 3 3 3 2 Ankyrin repeat AAA PF00004.29 ORY06775.1 - 1.2e-13 51.6 0.0 2.2e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Zot PF05707.12 ORY06775.1 - 0.0053 16.4 0.1 0.18 11.4 0.0 2.2 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_16 PF13191.6 ORY06775.1 - 0.024 15.1 0.0 0.047 14.1 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain TsaE PF02367.17 ORY06775.1 - 0.051 13.6 0.0 0.09 12.8 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 ORY06775.1 - 0.051 13.8 0.0 0.15 12.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain Glyco_hydro_11 PF00457.17 ORY06776.1 - 1.5e-74 249.4 20.8 1.8e-74 249.2 20.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 TDRP PF15683.5 ORY06776.1 - 0.024 14.6 0.2 0.048 13.6 0.2 1.4 1 0 0 1 1 1 0 Testis development-related protein DLH PF01738.18 ORY06777.1 - 1.5e-15 57.4 0.0 3e-15 56.4 0.0 1.5 1 1 0 1 1 1 1 Dienelactone hydrolase family Zn_clus PF00172.18 ORY06778.1 - 1.1e-07 31.9 12.7 2.1e-07 31.0 12.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dpy-30 PF05186.13 ORY06873.1 - 0.00027 20.6 0.1 0.38 10.5 0.0 2.6 2 0 0 2 2 2 2 Dpy-30 motif RMF PF04957.12 ORY06873.1 - 0.063 13.5 0.6 0.11 12.7 0.6 1.5 1 0 0 1 1 1 0 Ribosome modulation factor Gp138_N PF18352.1 ORY06874.1 - 0.046 13.8 0.0 0.08 13.0 0.0 1.4 1 0 0 1 1 1 0 Phage protein Gp138 N-terminal domain Forkhead PF00250.18 ORY06875.1 - 4.9e-24 84.4 0.0 8.4e-24 83.6 0.0 1.3 1 0 0 1 1 1 1 Forkhead domain Cactin_mid PF10312.9 ORY06876.1 - 3.7e-60 203.1 4.7 7e-60 202.2 4.7 1.5 1 0 0 1 1 1 1 Conserved mid region of cactin CactinC_cactus PF09732.9 ORY06876.1 - 5.4e-58 194.4 6.8 8.5e-58 193.7 6.8 1.3 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein SF3A2 PF16835.5 ORY06876.1 - 0.034 14.5 0.1 0.12 12.8 0.0 1.9 2 0 0 2 2 2 0 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) XLF PF09302.11 ORY06877.1 - 1.2e-45 155.9 0.1 1.2e-45 155.9 0.1 1.5 2 0 0 2 2 2 1 XLF-Cernunnos, XRcc4-like factor, NHEJ component KASH_CCD PF14662.6 ORY06879.1 - 0.1 12.4 1.3 2.1 8.2 0.3 2.1 1 1 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH DHR-2 PF06920.13 ORY06879.1 - 0.12 11.0 0.0 0.15 10.6 0.0 1.1 1 0 0 1 1 1 0 Dock homology region 2 Fungal_TACC PF12709.7 ORY06879.1 - 0.15 12.5 1.0 4.2 7.9 0.3 2.2 2 0 0 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins PROCN PF08083.11 ORY06880.1 - 2.8e-233 773.9 9.4 2.8e-233 773.9 9.4 2.1 2 0 0 2 2 2 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 ORY06880.1 - 2.2e-126 420.1 1.0 4e-126 419.3 1.0 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 ORY06880.1 - 4.4e-84 280.2 2.1 2e-57 193.6 0.2 3.0 2 0 0 2 2 2 2 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.11 ORY06880.1 - 5.8e-76 253.6 1.4 5.8e-76 253.6 1.4 2.0 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.9 ORY06880.1 - 5.6e-71 236.9 0.1 1.2e-70 235.8 0.1 1.6 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.9 ORY06880.1 - 3.7e-47 158.6 0.5 1e-46 157.2 0.5 1.8 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.11 ORY06880.1 - 9.5e-47 158.0 0.6 2.8e-46 156.4 0.1 2.1 2 0 0 2 2 2 1 PROCT (NUC072) domain Hom_end_hint PF05203.16 ORY06880.1 - 4.8e-07 30.0 0.0 1.2e-06 28.7 0.0 1.7 1 0 0 1 1 1 1 Hom_end-associated Hint Hom_end PF05204.14 ORY06880.1 - 0.021 15.0 0.0 0.3 11.3 0.0 2.6 2 0 0 2 2 2 0 Homing endonuclease DUF536 PF04394.14 ORY06880.1 - 1.5 8.7 7.7 0.12 12.2 2.2 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF536 Ribosomal_L34e PF01199.18 ORY06881.1 - 3.7e-43 145.8 2.5 5e-43 145.3 2.5 1.2 1 0 0 1 1 1 1 Ribosomal protein L34e Vps36-NZF-N PF16988.5 ORY06881.1 - 0.11 12.0 0.0 0.26 10.7 0.0 1.6 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Zn_clus PF00172.18 ORY06882.1 - 2.9e-06 27.3 11.0 2.9e-06 27.3 11.0 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TOH_N PF12549.8 ORY06882.1 - 0.038 13.8 0.5 0.13 12.2 0.5 1.9 1 0 0 1 1 1 0 Tyrosine hydroxylase N terminal Spt20 PF12090.8 ORY06882.1 - 0.12 12.0 3.1 0.25 10.9 3.1 1.5 1 0 0 1 1 1 0 Spt20 family Erg28 PF03694.13 ORY06883.1 - 0.018 15.4 0.1 0.038 14.4 0.0 1.5 2 0 0 2 2 2 0 Erg28 like protein 2-Hacid_dh_C PF02826.19 ORY06884.1 - 9.6e-33 113.0 0.0 1.3e-32 112.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 ORY06884.1 - 1.7e-09 37.5 0.0 2.2e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 ORY06884.1 - 0.1 12.8 0.0 0.33 11.1 0.0 1.8 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase CDH-cyt PF16010.5 ORY06885.1 - 1.6e-52 177.8 0.0 1.8e-52 177.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase RVP_2 PF08284.11 ORY06885.1 - 0.22 11.3 0.0 0.32 10.8 0.0 1.1 1 0 0 1 1 1 0 Retroviral aspartyl protease GIT_SHD PF08518.11 ORY06886.1 - 7.6e-22 76.6 8.3 2.6e-11 42.9 0.9 2.6 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT Rootletin PF15035.6 ORY06886.1 - 0.005 16.9 10.8 0.005 16.9 10.8 2.4 1 1 0 2 2 2 1 Ciliary rootlet component, centrosome cohesion Phage_GP20 PF06810.11 ORY06886.1 - 0.025 14.4 16.9 1 9.2 0.1 4.1 2 2 2 4 4 4 0 Phage minor structural protein GP20 Jnk-SapK_ap_N PF09744.9 ORY06886.1 - 0.027 14.7 30.1 0.15 12.2 5.4 3.7 2 1 1 3 3 3 0 JNK_SAPK-associated protein-1 Pox_A_type_inc PF04508.12 ORY06886.1 - 0.06 13.2 4.7 3.5 7.6 0.5 4.7 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat TACC_C PF05010.14 ORY06886.1 - 0.067 13.0 18.6 0.025 14.4 4.2 2.5 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal SHE3 PF17078.5 ORY06886.1 - 0.077 12.7 19.8 0.76 9.4 2.4 2.3 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 CENP-F_leu_zip PF10473.9 ORY06886.1 - 0.086 12.9 25.0 0.057 13.4 6.9 2.6 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 BLOC1_2 PF10046.9 ORY06886.1 - 0.13 12.6 12.2 3.5 8.0 0.3 3.9 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Gp-FAR-1 PF05823.12 ORY06886.1 - 0.15 12.4 2.0 4.4 7.6 1.1 3.2 2 1 1 3 3 3 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Syntaxin_2 PF14523.6 ORY06886.1 - 0.17 12.3 27.4 0.32 11.4 3.6 4.8 3 1 2 5 5 5 0 Syntaxin-like protein TnpV PF14198.6 ORY06886.1 - 0.23 11.5 2.5 0.71 9.9 2.5 1.8 1 0 0 1 1 1 0 Transposon-encoded protein TnpV Lectin_N PF03954.14 ORY06886.1 - 0.43 10.3 7.6 2.4 7.9 0.3 3.4 2 1 1 3 3 3 0 Hepatic lectin, N-terminal domain DUF4407 PF14362.6 ORY06886.1 - 0.44 9.9 21.0 0.61 9.4 14.6 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF2939 PF11159.8 ORY06886.1 - 0.49 10.8 2.6 0.84 10.1 1.0 2.3 2 0 0 2 2 1 0 Protein of unknown function (DUF2939) THP2 PF09432.10 ORY06886.1 - 0.56 10.3 9.1 0.063 13.3 2.2 2.6 1 1 1 2 2 2 0 Tho complex subunit THP2 Spc7 PF08317.11 ORY06886.1 - 0.6 8.9 26.6 0.6 8.9 8.4 2.4 2 0 0 2 2 2 0 Spc7 kinetochore protein bZIP_1 PF00170.21 ORY06886.1 - 1.7 8.8 17.0 0.32 11.1 0.7 4.3 3 1 0 4 4 4 0 bZIP transcription factor HAUS-augmin3 PF14932.6 ORY06886.1 - 2.1 7.8 22.2 0.66 9.5 6.8 2.4 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 LXG PF04740.12 ORY06886.1 - 2.7 7.6 13.3 1.4 8.6 0.5 4.2 4 1 0 4 4 4 0 LXG domain of WXG superfamily ERM PF00769.19 ORY06886.1 - 2.7 7.7 28.2 0.42 10.4 7.6 2.4 1 1 0 2 2 2 0 Ezrin/radixin/moesin family DUF1664 PF07889.12 ORY06886.1 - 3.3 7.8 13.0 6.6 6.8 0.6 4.3 4 0 0 4 4 4 0 Protein of unknown function (DUF1664) AAA_13 PF13166.6 ORY06886.1 - 3.8 6.0 17.1 0.2 10.2 6.3 2.2 1 1 0 2 2 2 0 AAA domain HIP1_clath_bdg PF16515.5 ORY06886.1 - 7.9 7.2 25.8 2.3 8.9 6.5 3.6 2 1 1 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Exonuc_VII_S PF02609.16 ORY06886.1 - 8.1 6.6 7.2 2.9 8.0 0.1 3.2 3 0 0 3 3 3 0 Exonuclease VII small subunit SlyX PF04102.12 ORY06886.1 - 8.2 7.1 18.8 2 9.1 0.3 4.4 2 2 2 4 4 4 0 SlyX EzrA PF06160.12 ORY06886.1 - 8.9 4.3 17.6 1.6 6.8 6.0 2.2 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA CC2-LZ PF16516.5 ORY06886.1 - 9.7 6.6 20.0 1.6 9.2 0.7 3.7 2 2 1 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator ING PF12998.7 ORY06887.1 - 1.8e-23 83.0 4.6 3.5e-23 82.1 4.6 1.5 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 ORY06887.1 - 3e-06 27.0 8.5 5.1e-06 26.3 8.5 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 ORY06887.1 - 0.0054 16.3 2.4 0.009 15.5 2.4 1.4 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 ORY06887.1 - 0.007 16.6 0.1 0.018 15.3 0.1 1.6 1 0 0 1 1 1 1 PHD-like zinc-binding domain FliD_C PF07195.12 ORY06887.1 - 0.038 13.4 2.6 0.94 8.8 0.3 2.1 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus TFIIA PF03153.13 ORY06887.1 - 1.9 8.4 16.6 3.6 7.5 16.6 1.5 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Hist_deacetyl PF00850.19 ORY06888.1 - 5.6e-75 252.7 0.0 7.6e-75 252.2 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain DUF4695 PF15766.5 ORY06888.1 - 0.033 14.4 0.6 0.06 13.6 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4695) Fungal_trans PF04082.18 ORY06889.1 - 9.3e-16 57.6 0.0 1.5e-15 56.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY06889.1 - 5.3e-09 36.1 13.0 5.3e-09 36.1 13.0 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Alk_phosphatase PF00245.20 ORY06890.1 - 3.4e-108 362.3 0.0 5.4e-108 361.6 0.0 1.3 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 ORY06890.1 - 0.00035 20.0 0.0 0.0006 19.2 0.0 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily Methyltransf_31 PF13847.6 ORY06891.1 - 1.2e-05 25.1 0.0 1.7e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY06891.1 - 1.8e-05 25.3 0.0 3.6e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORY06891.1 - 0.0083 15.5 0.0 0.013 14.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 ORY06891.1 - 0.13 13.0 0.0 0.25 12.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain RNA_pol_Rpc34 PF05158.12 ORY06892.1 - 2.4e-69 234.3 0.1 6.2e-68 229.7 0.1 2.0 1 1 0 1 1 1 1 RNA polymerase Rpc34 subunit MarR_2 PF12802.7 ORY06892.1 - 0.00067 19.5 0.0 0.0016 18.3 0.0 1.6 1 0 0 1 1 1 1 MarR family SelB-wing_1 PF09105.10 ORY06892.1 - 0.029 14.4 0.0 0.062 13.3 0.0 1.5 1 0 0 1 1 1 0 Elongation factor SelB, winged helix Rrf2 PF02082.20 ORY06892.1 - 0.029 14.7 0.3 0.17 12.3 0.0 2.3 3 0 0 3 3 3 0 Transcriptional regulator MarR PF01047.22 ORY06892.1 - 0.03 14.2 0.0 0.067 13.1 0.0 1.6 1 0 0 1 1 1 0 MarR family HTH_Crp_2 PF13545.6 ORY06892.1 - 0.033 14.1 0.0 0.11 12.5 0.0 1.8 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_24 PF13412.6 ORY06892.1 - 0.047 13.2 0.1 0.15 11.6 0.1 1.9 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding B-block_TFIIIC PF04182.12 ORY06892.1 - 0.058 13.6 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC MqsR_toxin PF15723.5 ORY06892.1 - 0.065 13.6 0.3 4 7.9 0.0 2.7 3 0 0 3 3 3 0 Motility quorum-sensing regulator, toxin of MqsA HxlR PF01638.17 ORY06892.1 - 0.13 12.1 0.2 0.32 10.9 0.0 1.7 2 0 0 2 2 2 0 HxlR-like helix-turn-helix EndIII_4Fe-2S PF10576.9 ORY06892.1 - 9.8 6.7 6.9 2.2 8.7 1.3 2.3 2 0 0 2 2 2 0 Iron-sulfur binding domain of endonuclease III CFEM PF05730.11 ORY06893.1 - 3.9 7.6 7.1 10 6.3 3.7 2.6 2 1 0 2 2 2 0 CFEM domain Amidohydro_3 PF07969.11 ORY06894.1 - 4e-61 207.9 0.0 5e-61 207.6 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 ORY06894.1 - 2.9e-05 23.5 0.0 0.0002 20.8 0.0 2.1 2 0 0 2 2 2 1 Amidohydrolase family NAS PF03059.16 ORY06895.1 - 4e-59 200.2 0.3 4.3e-31 108.3 0.1 2.0 2 0 0 2 2 2 2 Nicotianamine synthase protein Methyltransf_31 PF13847.6 ORY06895.1 - 5.8e-09 35.9 0.0 1.4e-07 31.4 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY06895.1 - 0.025 15.2 0.0 5.3 7.8 0.0 2.8 3 0 0 3 3 3 0 Methyltransferase domain Methyltransf_25 PF13649.6 ORY06895.1 - 0.028 15.1 0.0 2.1 9.1 0.0 2.4 1 1 1 2 2 2 0 Methyltransferase domain PAN_4 PF14295.6 ORY06896.1 - 2e-08 34.0 7.1 3.2e-05 23.7 1.6 2.9 2 1 0 2 2 2 2 PAN domain PAN_3 PF08277.12 ORY06896.1 - 0.00023 20.9 2.1 0.81 9.5 0.1 3.0 2 0 0 2 2 2 2 PAN-like domain eRF1_1 PF03463.15 ORY06897.1 - 7.1e-48 161.9 0.0 1.1e-47 161.3 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_3 PF03465.15 ORY06897.1 - 1.3e-15 57.8 0.0 2.4e-15 57.0 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_2 PF03464.15 ORY06897.1 - 1.9e-14 54.1 0.0 3e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 2 adh_short_C2 PF13561.6 ORY06898.1 - 1.6e-52 178.4 0.3 2.1e-52 178.0 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY06898.1 - 1.1e-41 142.4 0.2 1.4e-41 142.1 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORY06898.1 - 2.5e-11 43.8 0.0 4.4e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 KR domain ThiF PF00899.21 ORY06898.1 - 0.0092 15.4 0.1 0.49 9.7 0.0 2.6 1 1 1 2 2 2 1 ThiF family Epimerase PF01370.21 ORY06898.1 - 0.021 14.3 0.1 0.07 12.6 0.1 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family HTH_Tnp_IS630 PF01710.16 ORY06898.1 - 0.12 12.4 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Transposase NAD_binding_8 PF13450.6 ORY06899.1 - 2.5e-12 46.8 0.0 6.3e-12 45.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.19 ORY06899.1 - 2.8e-10 39.2 0.3 2.6e-08 32.8 0.1 2.5 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 ORY06899.1 - 1.3e-06 27.9 0.0 8.6e-06 25.2 0.0 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ORY06899.1 - 5.6e-06 26.2 0.0 0.0089 15.6 0.0 3.0 2 1 1 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ORY06899.1 - 2.5e-05 23.7 0.0 0.032 13.5 0.0 2.4 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ORY06899.1 - 0.00012 22.1 0.0 0.00064 19.7 0.0 2.2 3 0 0 3 3 3 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 ORY06899.1 - 0.00089 18.5 0.0 0.42 9.7 0.0 2.8 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 ORY06899.1 - 0.032 13.5 0.0 0.078 12.2 0.0 1.5 2 0 0 2 2 2 0 Thi4 family HI0933_like PF03486.14 ORY06899.1 - 0.19 10.4 0.0 0.32 9.6 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Rick_17kDa_Anti PF05433.15 ORY06901.1 - 5.9e-06 26.0 11.0 1e-05 25.3 11.0 1.4 1 0 0 1 1 1 1 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.6 ORY06901.1 - 0.052 13.5 8.6 0.095 12.7 8.6 1.4 1 0 0 1 1 1 0 Glycine zipper Gly-zipper_YMGG PF13441.6 ORY06901.1 - 0.79 9.5 13.0 1.5 8.6 13.0 1.4 1 0 0 1 1 1 0 YMGG-like Gly-zipper TraT PF05818.12 ORY06901.1 - 0.8 9.3 1.7 1.5 8.5 1.7 1.3 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein Cornifin PF02389.15 ORY06901.1 - 2.5 8.3 15.9 0.3 11.3 6.0 2.1 1 1 1 2 2 2 0 Cornifin (SPRR) family Zip PF02535.22 ORY06901.1 - 4.4 6.4 3.9 1.4 8.1 1.2 1.5 2 0 0 2 2 2 0 ZIP Zinc transporter Apt1 PF10351.9 ORY06901.1 - 6.5 5.5 11.5 3.2 6.5 6.4 2.0 2 0 0 2 2 2 0 Golgi-body localisation protein domain cNMPbd_u2 PF16643.5 ORY06902.1 - 1.6e-40 139.1 19.3 2.8e-40 138.4 17.1 2.4 2 0 0 2 2 2 1 Unstructured region on cNMP-binding protein cNMP_binding PF00027.29 ORY06902.1 - 1.7e-33 114.6 0.0 6e-19 67.9 0.0 3.3 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain LRR_6 PF13516.6 ORY06902.1 - 4.5e-10 38.8 4.8 1.2 9.4 0.0 8.6 9 0 0 9 9 9 2 Leucine Rich repeat LRR_4 PF12799.7 ORY06902.1 - 1.6e-08 34.7 0.3 0.051 14.0 0.1 5.8 5 1 1 6 6 6 2 Leucine Rich repeats (2 copies) F-box PF00646.33 ORY06902.1 - 0.00041 20.2 2.3 0.0032 17.3 0.1 3.2 2 1 0 2 2 2 1 F-box domain LRR_1 PF00560.33 ORY06902.1 - 0.0011 19.2 5.2 75 4.5 0.0 7.0 7 0 0 7 7 7 0 Leucine Rich Repeat LRR_8 PF13855.6 ORY06902.1 - 0.0038 17.0 0.0 6.1 6.7 0.2 3.1 2 1 0 2 2 2 2 Leucine rich repeat F-box-like PF12937.7 ORY06902.1 - 0.0089 15.9 0.2 0.17 11.8 0.0 2.6 2 0 0 2 2 2 1 F-box-like RNase_PH PF01138.21 ORY06903.1 - 1.8e-39 135.3 0.1 2.6e-39 134.7 0.1 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 SNF2_N PF00176.23 ORY06904.1 - 4.6e-54 183.5 0.2 1.3e-53 182.0 0.3 1.6 1 1 1 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ORY06904.1 - 9.8e-20 71.0 0.0 1.6e-17 63.8 0.0 3.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain VIGSSK PF14773.6 ORY06904.1 - 3.4e-19 68.7 0.2 3.4e-19 68.7 0.2 2.6 3 0 0 3 3 3 1 Helicase-associated putative binding domain, C-terminal ResIII PF04851.15 ORY06904.1 - 1.8e-09 37.9 0.3 1.5e-08 34.9 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 ORY06904.1 - 7.4e-06 25.4 0.1 1.6e-05 24.3 0.1 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase DEAD PF00270.29 ORY06904.1 - 4.6e-05 23.3 0.1 0.00043 20.1 0.0 2.5 3 0 0 3 3 3 1 DEAD/DEAH box helicase SAND PF01342.21 ORY06904.1 - 0.11 12.2 0.0 0.28 10.9 0.0 1.6 1 0 0 1 1 1 0 SAND domain Vfa1 PF08432.10 ORY06905.1 - 0.14 12.5 8.5 0.18 12.1 8.5 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Mpp10 PF04006.12 ORY06905.1 - 0.52 8.7 20.6 0.61 8.5 20.6 1.1 1 0 0 1 1 1 0 Mpp10 protein SDA1 PF05285.12 ORY06905.1 - 0.56 9.6 25.2 0.67 9.3 25.2 1.1 1 0 0 1 1 1 0 SDA1 CNDH2_C PF16858.5 ORY06905.1 - 0.56 10.0 12.6 0.68 9.7 12.6 1.2 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term CDC45 PF02724.14 ORY06905.1 - 0.64 8.2 21.0 0.76 8.0 21.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 ORY06905.1 - 1.8 6.7 25.2 1.9 6.6 25.2 1.0 1 0 0 1 1 1 0 Nop14-like family NPR3 PF03666.13 ORY06905.1 - 2.7 6.7 7.5 3.1 6.5 7.5 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SAPS PF04499.15 ORY06905.1 - 6.1 5.5 12.6 6.6 5.4 12.6 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF2457 PF10446.9 ORY06905.1 - 6.4 5.8 37.3 8.8 5.3 37.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF2722 PF10846.8 ORY06905.1 - 7 5.5 18.5 9 5.1 18.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Fungal_trans PF04082.18 ORY06906.1 - 4.5e-20 71.8 0.1 1.3e-19 70.3 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY06906.1 - 1.6e-05 24.9 10.3 3e-05 24.0 10.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1631 PF07793.11 ORY06906.1 - 0.079 11.4 1.7 0.15 10.5 1.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) FMO-like PF00743.19 ORY06907.1 - 6.3e-14 51.3 1.0 1.4e-12 46.9 0.3 2.3 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 ORY06907.1 - 1.3e-09 38.1 0.0 3.4e-09 36.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ORY06907.1 - 0.022 14.3 0.0 0.28 10.7 0.0 2.5 2 2 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 ORY06907.1 - 0.035 13.4 0.0 0.42 9.8 0.0 2.5 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase AMP-binding PF00501.28 ORY06908.1 - 6.6e-89 298.4 0.0 8.5e-89 298.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORY06908.1 - 2.8e-13 50.6 0.3 7.9e-13 49.2 0.3 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Post_transc_reg PF13797.6 ORY06908.1 - 0.2 11.5 0.6 0.58 10.1 0.1 1.9 2 0 0 2 2 2 0 Post-transcriptional regulator adh_short_C2 PF13561.6 ORY06909.1 - 7.7e-49 166.4 0.0 9.3e-49 166.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY06909.1 - 3.2e-41 141.0 0.0 4.1e-41 140.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORY06909.1 - 3.9e-14 53.0 0.1 5.8e-14 52.4 0.1 1.1 1 0 0 1 1 1 1 KR domain Tex_YqgF PF16921.5 ORY06909.1 - 0.11 12.9 0.0 11 6.6 0.0 2.3 2 0 0 2 2 2 0 Tex protein YqgF-like domain Epimerase PF01370.21 ORY06909.1 - 0.15 11.5 0.1 0.33 10.4 0.1 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family adh_short PF00106.25 ORY06910.1 - 5.5e-34 117.3 0.0 7.2e-34 117.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY06910.1 - 2.1e-27 96.2 0.0 2.8e-27 95.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY06910.1 - 0.00029 20.8 0.2 0.00062 19.7 0.0 1.6 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 ORY06910.1 - 0.0016 18.0 0.0 0.0027 17.2 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 ORY06910.1 - 0.069 12.1 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Aldedh PF00171.22 ORY06911.1 - 5.7e-159 529.5 0.3 6.4e-159 529.4 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 ORY06911.1 - 0.0085 15.6 0.0 2.2 7.7 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) TRI12 PF06609.13 ORY06913.1 - 3.1e-35 121.7 18.6 3.7e-35 121.4 18.6 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 ORY06913.1 - 6.2e-26 91.2 39.9 6.2e-26 91.2 39.9 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY06913.1 - 5.5e-09 35.4 12.2 5.5e-09 35.4 12.2 3.2 2 1 1 3 3 3 1 Sugar (and other) transporter EthD PF07110.11 ORY06914.1 - 3.8e-17 63.2 1.0 4.8e-17 62.9 1.0 1.1 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 ORY06914.1 - 0.00016 22.1 0.4 0.00024 21.5 0.4 1.2 1 0 0 1 1 1 1 Methylmuconolactone methyl-isomerase ADH_zinc_N PF00107.26 ORY06915.1 - 2.9e-23 82.3 0.5 5.1e-23 81.5 0.5 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ORY06915.1 - 5.6e-19 68.0 0.7 1.1e-18 67.1 0.7 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 ORY06915.1 - 4.2e-05 22.9 0.0 7e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 ORY06915.1 - 0.00071 19.0 0.0 0.0013 18.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_25 PF13649.6 ORY06915.1 - 0.0029 18.3 0.1 0.0063 17.2 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 ORY06915.1 - 0.0039 16.5 0.0 0.0055 16.0 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase TrkA_N PF02254.18 ORY06915.1 - 0.013 15.7 0.0 0.021 15.1 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain Methyltransf_11 PF08241.12 ORY06915.1 - 0.015 16.0 0.2 0.044 14.4 0.2 1.9 1 1 0 1 1 1 0 Methyltransferase domain PglD_N PF17836.1 ORY06915.1 - 0.018 15.7 0.7 0.047 14.3 0.1 2.0 2 0 0 2 2 2 0 PglD N-terminal domain UCR_14kD PF02271.16 ORY06915.1 - 0.018 15.0 0.1 1.6 8.8 0.1 2.5 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase complex 14kD subunit 3HCDH_N PF02737.18 ORY06915.1 - 0.059 13.2 0.3 0.098 12.5 0.3 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Abhydrolase_2 PF02230.16 ORY06916.1 - 0.0091 15.8 0.0 0.014 15.2 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 ORY06917.1 - 4.5e-46 157.4 0.0 5.5e-46 157.1 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 ORY06917.1 - 4.2e-08 32.5 1.2 2.7e-07 29.8 1.2 2.0 1 1 0 1 1 1 1 Carboxylesterase family Acyl-CoA_dh_1 PF00441.24 ORY06918.1 - 1.5e-22 80.4 0.2 2.6e-22 79.6 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 ORY06918.1 - 9.1e-13 48.9 0.0 2.3e-12 47.6 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 ORY06918.1 - 3.1e-06 27.5 0.0 5.1e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 ORY06918.1 - 7.1e-06 26.1 0.0 2e-05 24.7 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain RNA_pol_Rbc25 PF08292.12 ORY06918.1 - 0.013 15.8 0.0 0.025 14.8 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase III subunit Rpc25 APH PF01636.23 ORY06919.1 - 9.2e-39 133.8 0.0 1.5e-38 133.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 ORY06919.1 - 0.00048 19.8 0.1 0.0013 18.4 0.0 1.6 2 0 0 2 2 2 1 RIO1 family DUF1679 PF07914.11 ORY06919.1 - 0.0017 17.3 0.0 1.2 7.9 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF1679) Kdo PF06293.14 ORY06919.1 - 0.0026 17.2 0.0 0.0068 15.8 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 ORY06919.1 - 0.0031 17.1 0.0 0.005 16.4 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.20 ORY06919.1 - 0.017 14.5 0.0 0.033 13.5 0.0 1.4 1 0 0 1 1 1 0 Ecdysteroid kinase Glyco_hydro_47 PF01532.20 ORY06920.1 - 5.5e-114 381.6 0.0 7.6e-114 381.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 SR-25 PF10500.9 ORY06920.1 - 0.33 10.5 23.9 0.59 9.7 23.9 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Apt1 PF10351.9 ORY06920.1 - 0.44 9.3 7.5 0.61 8.9 7.5 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Peroxin-3 PF04882.12 ORY06920.1 - 1.5 7.7 6.1 2.2 7.2 6.1 1.2 1 0 0 1 1 1 0 Peroxin-3 Macoilin PF09726.9 ORY06920.1 - 4 5.9 7.3 5.7 5.4 7.3 1.1 1 0 0 1 1 1 0 Macoilin family TFIIF_alpha PF05793.12 ORY06920.1 - 9.8 4.6 10.9 16 3.9 10.9 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) KAR9 PF08580.10 ORY06921.1 - 3 6.3 10.0 3.1 6.2 10.0 1.0 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Glyco_transf_8 PF01501.20 ORY06999.1 - 1.8e-13 50.7 0.0 5.7e-13 49.0 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mito_carr PF00153.27 ORY07000.1 - 1.1e-42 143.8 0.3 1.1e-15 57.2 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein NmrA PF05368.13 ORY07001.1 - 8e-25 87.7 0.0 2.3e-24 86.3 0.0 1.6 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ORY07001.1 - 2.9e-07 30.5 0.0 4.4e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding TrkA_N PF02254.18 ORY07001.1 - 0.019 15.3 0.0 0.048 13.9 0.0 1.6 2 0 0 2 2 2 0 TrkA-N domain GH131_N PF18271.1 ORY07002.1 - 1e-71 241.6 0.0 1.2e-71 241.4 0.0 1.0 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain FluMu_N PF17891.1 ORY07002.1 - 0.076 12.8 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Mu-like prophage FluMu N-terminal domain PGM_PMM_I PF02878.16 ORY07004.1 - 0.18 11.5 0.0 0.29 10.9 0.0 1.2 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I BATS PF06968.13 ORY07005.1 - 0.052 13.7 0.0 0.084 13.0 0.0 1.3 1 0 0 1 1 1 0 Biotin and Thiamin Synthesis associated domain DMP1 PF07263.11 ORY07007.1 - 0.12 11.3 0.0 0.14 11.0 0.0 1.1 1 0 0 1 1 1 0 Dentin matrix protein 1 (DMP1) DUF4690 PF15756.5 ORY07009.1 - 0.047 14.3 0.0 0.11 13.1 0.0 1.6 1 0 0 1 1 1 0 Small Novel Rich in Cartilage DUF4514 PF14986.6 ORY07009.1 - 0.21 11.6 0.2 0.37 10.8 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4514) NmrA PF05368.13 ORY07010.1 - 1.7e-10 40.8 0.0 1.1e-09 38.3 0.0 1.9 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ORY07010.1 - 2.3e-06 27.6 0.0 4.7e-06 26.6 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding Piwi PF02171.17 ORY07012.1 - 6.2e-26 91.3 0.0 1.2e-25 90.4 0.0 1.4 1 1 0 1 1 1 1 Piwi domain Macoilin PF09726.9 ORY07013.1 - 8.8 4.7 6.9 12 4.4 6.9 1.1 1 0 0 1 1 1 0 Macoilin family Aldolase_II PF00596.21 ORY07014.1 - 1.8e-46 158.4 1.2 3.1e-46 157.7 1.2 1.4 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Lactamase_B PF00753.27 ORY07015.1 - 2.9e-05 24.2 0.1 6.3e-05 23.1 0.1 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily MFS_1 PF07690.16 ORY07016.1 - 1e-22 80.6 34.2 6.4e-22 78.0 32.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4698 PF15769.5 ORY07016.1 - 0.2 10.7 0.9 0.28 10.2 0.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4698) p450 PF00067.22 ORY07018.1 - 1.6e-69 234.8 0.0 2e-69 234.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 TRI12 PF06609.13 ORY07019.1 - 4.2e-59 200.5 24.3 5.3e-59 200.2 24.3 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 ORY07019.1 - 3.9e-19 68.8 57.4 2.2e-18 66.3 54.3 3.0 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY07019.1 - 1.6e-06 27.3 13.1 1.6e-06 27.3 13.1 3.6 2 2 1 3 3 3 2 Sugar (and other) transporter adh_short PF00106.25 ORY07020.1 - 9.3e-21 74.2 0.0 1.1e-20 73.9 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY07020.1 - 3.6e-17 62.7 0.0 4.4e-17 62.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase GMC_oxred_C PF05199.13 ORY07021.1 - 1.6e-29 103.3 0.0 2.7e-29 102.5 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 ORY07021.1 - 3.5e-17 62.7 0.0 1e-14 54.7 0.0 2.4 1 1 0 1 1 1 1 GMC oxidoreductase Sugar_tr PF00083.24 ORY07022.1 - 1.2e-17 63.9 9.9 1.6e-17 63.6 9.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY07022.1 - 3.3e-06 26.3 12.8 4.2e-06 25.9 12.8 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily PUCC PF03209.15 ORY07022.1 - 2.9e-05 23.2 3.5 3.5e-05 23.0 3.5 1.1 1 0 0 1 1 1 1 PUCC protein FtsK_4TM PF13491.6 ORY07022.1 - 1 9.0 8.4 0.31 10.7 4.6 1.9 2 0 0 2 2 2 0 4TM region of DNA translocase FtsK/SpoIIIE Glyco_hydro_25 PF01183.20 ORY07023.1 - 2e-40 138.9 0.1 2.3e-40 138.7 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 RTA1 PF04479.13 ORY07024.1 - 1.8e-35 122.4 2.9 1.8e-35 122.4 2.9 1.5 2 0 0 2 2 2 1 RTA1 like protein Fungal_trans_2 PF11951.8 ORY07025.1 - 8.4e-20 70.9 2.0 1.1e-19 70.5 2.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY07025.1 - 3.6e-05 23.8 8.2 8.1e-05 22.7 8.2 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_25 PF13649.6 ORY07026.1 - 2.9e-13 50.4 0.0 1.5e-12 48.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY07026.1 - 1.5e-12 48.0 0.0 3.8e-12 46.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY07026.1 - 6.7e-12 45.6 0.0 8.1e-12 45.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY07026.1 - 4.9e-11 43.3 0.0 8.6e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY07026.1 - 2e-05 24.5 0.0 0.00013 21.8 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORY07026.1 - 0.0088 15.4 0.0 0.021 14.2 0.0 1.6 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.19 ORY07026.1 - 0.065 13.3 0.0 0.11 12.5 0.0 1.3 1 1 0 1 1 1 0 FtsJ-like methyltransferase MTS PF05175.14 ORY07026.1 - 0.2 11.2 0.0 0.47 10.0 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase small domain FAD_binding_4 PF01565.23 ORY07027.1 - 3.9e-25 88.2 0.0 6.2e-25 87.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.19 ORY07027.1 - 6.9e-09 35.7 0.0 1.1e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_3 PF01494.19 ORY07028.1 - 4.6e-14 52.4 0.0 4.2e-13 49.3 0.0 2.1 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 ORY07028.1 - 9.4e-07 28.3 0.0 0.00012 21.5 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ORY07028.1 - 2.8e-06 26.7 1.4 4.5e-06 26.0 1.4 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 ORY07028.1 - 2.2e-05 24.6 0.4 0.00011 22.3 0.4 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 ORY07028.1 - 4.3e-05 22.8 0.1 6e-05 22.3 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.14 ORY07028.1 - 7.5e-05 21.6 0.1 0.03 13.0 0.6 2.1 2 0 0 2 2 2 2 HI0933-like protein DAO PF01266.24 ORY07028.1 - 0.001 18.8 5.1 0.015 14.9 2.1 2.6 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 ORY07028.1 - 0.0064 17.0 0.3 0.037 14.6 0.4 2.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 ORY07028.1 - 0.018 14.4 0.3 0.035 13.5 0.3 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 ORY07028.1 - 0.021 14.1 0.2 0.21 10.8 0.9 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AflR PF08493.10 ORY07030.1 - 0.94 8.9 3.5 1.2 8.5 3.5 1.3 1 0 0 1 1 1 0 Aflatoxin regulatory protein Hydrolase_6 PF13344.6 ORY07032.1 - 2.8e-23 82.0 0.0 5.8e-23 80.9 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ORY07032.1 - 5.8e-13 48.7 0.0 2.6e-12 46.6 0.0 2.2 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 ORY07032.1 - 0.12 12.6 0.0 30 4.8 0.0 2.8 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase zf-U1 PF06220.12 ORY07033.1 - 1.9 8.3 4.4 0.94 9.3 1.3 2.2 2 0 0 2 2 2 0 U1 zinc finger PI-PLC-X PF00388.19 ORY07036.1 - 3.5e-62 208.3 0.0 6.3e-62 207.4 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 ORY07036.1 - 6.5e-43 145.7 0.1 1.1e-42 144.9 0.1 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain GDPD PF03009.17 ORY07036.1 - 0.0015 18.3 0.0 0.0048 16.7 0.0 1.7 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family Sel_put PF04328.13 ORY07039.1 - 0.12 12.5 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 Selenoprotein, putative NUC130_3NT PF08158.12 ORY07039.1 - 0.12 12.7 0.0 0.38 11.1 0.0 1.8 1 0 0 1 1 1 0 NUC130/3NT domain Pkinase PF00069.25 ORY07041.1 - 7.1e-33 114.1 0.0 2.9e-32 112.1 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY07041.1 - 4.6e-19 68.7 0.0 1.1e-18 67.5 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 ORY07041.1 - 0.0024 17.2 0.0 0.0062 15.9 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 ORY07041.1 - 0.1 12.2 0.0 0.3 10.7 0.0 1.7 2 0 0 2 2 2 0 RIO1 family Ank PF00023.30 ORY07042.1 - 0.0018 18.7 1.7 0.16 12.5 0.1 3.1 2 2 1 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 ORY07042.1 - 0.027 15.0 0.1 3.4 8.5 0.0 3.1 2 1 0 2 2 2 0 Ankyrin repeat Ank_4 PF13637.6 ORY07042.1 - 0.093 13.3 0.0 3.8 8.2 0.0 2.5 2 1 0 2 2 2 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 ORY07042.1 - 0.15 12.7 0.0 0.39 11.4 0.0 1.8 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) Chitin_bind_1 PF00187.19 ORY07043.1 - 0.0025 18.3 37.4 0.054 14.0 12.9 3.9 2 1 1 3 3 3 2 Chitin recognition protein LysM PF01476.20 ORY07043.1 - 0.19 11.8 0.0 0.33 11.1 0.0 1.5 1 0 0 1 1 1 0 LysM domain HET PF06985.11 ORY07044.1 - 9.3e-26 90.9 0.1 1.8e-25 90.0 0.1 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Piwi PF02171.17 ORY07045.1 - 3e-21 76.0 0.3 3.2e-21 75.9 0.3 1.0 1 0 0 1 1 1 1 Piwi domain Peroxidase_2 PF01328.17 ORY07046.1 - 1.2e-45 156.4 0.0 1.5e-45 156.0 0.0 1.0 1 0 0 1 1 1 1 Peroxidase, family 2 HET PF06985.11 ORY07048.1 - 4.1e-28 98.6 0.0 4.7e-28 98.4 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) zf-C3HC4_3 PF13920.6 ORY07049.1 - 9.1e-10 38.3 6.5 1.8e-09 37.3 6.5 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORY07049.1 - 2.4e-08 33.8 6.3 4.1e-08 33.1 6.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 ORY07049.1 - 3.2e-08 33.3 4.6 7.6e-08 32.1 4.6 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 ORY07049.1 - 1.2e-07 31.5 7.7 7.7e-07 28.9 7.7 2.1 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 ORY07049.1 - 1.4e-07 31.8 6.6 2.6e-07 30.9 6.6 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 ORY07049.1 - 4.9e-07 29.5 5.9 1.3e-06 28.1 1.9 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORY07049.1 - 1.4e-06 28.2 1.5 1.4e-06 28.2 1.5 2.3 2 1 1 3 3 3 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 ORY07049.1 - 0.0078 16.4 6.3 0.077 13.2 6.9 2.1 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 ORY07049.1 - 0.014 15.7 3.6 0.03 14.6 3.6 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain Zn_Tnp_IS91 PF14319.6 ORY07049.1 - 0.017 15.2 2.2 0.017 15.2 2.2 2.1 1 1 1 2 2 2 0 Transposase zinc-binding domain IBR PF01485.21 ORY07049.1 - 0.14 12.4 2.8 2.4 8.4 1.3 2.3 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain zf-RING_4 PF14570.6 ORY07049.1 - 0.36 10.7 5.4 0.93 9.3 5.4 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_10 PF16685.5 ORY07049.1 - 6 7.1 8.9 1.5 9.0 3.0 2.2 1 1 1 2 2 2 0 zinc RING finger of MSL2 Gin PF10764.9 ORY07049.1 - 9 6.3 6.5 14 5.8 2.4 2.3 2 0 0 2 2 2 0 Inhibitor of sigma-G Gin DNApol_Exo PF18136.1 ORY07050.1 - 3e-104 348.1 0.0 4.6e-104 347.5 0.0 1.3 1 0 0 1 1 1 1 DNA mitochondrial polymerase exonuclease domain DNA_pol_A PF00476.20 ORY07050.1 - 3.3e-39 135.0 0.0 5e-39 134.4 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family A DNA_pol_A_exo1 PF01612.20 ORY07050.1 - 0.16 11.7 0.0 3.4 7.4 0.0 2.3 2 0 0 2 2 2 0 3'-5' exonuclease COesterase PF00135.28 ORY07129.1 - 9.5e-86 288.7 0.2 1.4e-85 288.2 0.2 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 ORY07129.1 - 1.2e-06 28.6 0.7 1.1e-05 25.3 0.6 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold OAD_gamma PF04277.13 ORY07130.1 - 0.026 15.1 1.0 0.026 15.1 1.0 1.9 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Peptidase_S41 PF03572.18 ORY07131.1 - 3.7e-09 36.3 0.0 1.4e-08 34.5 0.0 1.8 1 1 0 1 1 1 1 Peptidase family S41 Kelch_5 PF13854.6 ORY07131.1 - 0.035 14.1 0.7 0.082 12.9 0.7 1.7 1 0 0 1 1 1 0 Kelch motif peroxidase PF00141.23 ORY07135.1 - 1.9e-33 116.1 0.0 3.1e-33 115.4 0.0 1.3 1 0 0 1 1 1 1 Peroxidase Fungal_trans_2 PF11951.8 ORY07136.1 - 6.8e-11 41.6 0.0 1.2e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY07136.1 - 4.8e-10 39.4 5.7 8.2e-10 38.7 5.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1275 PF06912.11 ORY07140.1 - 1.9e-36 125.8 14.6 2e-34 119.2 14.6 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1275) Cupin_1 PF00190.22 ORY07141.1 - 3.8e-39 133.7 0.0 5.6e-20 71.5 0.0 2.1 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 ORY07141.1 - 7e-24 83.3 0.5 7.3e-12 44.8 0.1 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 ORY07141.1 - 5.3e-08 32.4 0.0 0.0036 17.0 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.19 ORY07141.1 - 0.00026 20.9 0.3 0.08 12.9 0.1 2.4 2 0 0 2 2 2 2 AraC-like ligand binding domain CENP-C_C PF11699.8 ORY07141.1 - 0.015 15.5 0.0 1 9.6 0.0 2.6 2 0 0 2 2 2 0 Mif2/CENP-C like MannoseP_isomer PF01050.18 ORY07141.1 - 0.12 12.3 0.0 0.82 9.5 0.0 1.9 2 0 0 2 2 2 0 Mannose-6-phosphate isomerase UBM PF14377.6 ORY07142.1 - 0.037 13.5 0.6 0.064 12.7 0.6 1.4 1 0 0 1 1 1 0 Ubiquitin binding region zf-C2H2_4 PF13894.6 ORY07144.1 - 1 10.4 0.1 1 10.4 0.1 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.26 ORY07145.1 - 0.011 16.2 0.7 0.011 16.2 0.7 3.9 5 0 0 5 5 5 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY07145.1 - 0.074 13.9 0.5 0.074 13.9 0.5 4.1 4 0 0 4 4 4 0 C2H2-type zinc finger zf_UBZ PF18439.1 ORY07145.1 - 0.26 10.9 0.1 0.26 10.9 0.1 3.8 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger Sugar_tr PF00083.24 ORY07147.1 - 1.1e-96 324.5 30.1 1.2e-88 297.9 18.9 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 ORY07147.1 - 6.3e-15 55.0 34.2 3.3e-14 52.6 29.0 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily HET PF06985.11 ORY07148.1 - 4e-25 88.9 0.0 5.6e-25 88.4 0.0 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) BTB PF00651.31 ORY07150.1 - 0.0022 18.2 0.0 0.0034 17.6 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain FH2 PF02181.23 ORY07151.1 - 4.6e-82 276.1 7.1 4.6e-82 276.1 7.1 2.1 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.13 ORY07151.1 - 1.6e-67 226.7 0.0 1.6e-67 226.7 0.0 2.0 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 ORY07151.1 - 1e-52 178.6 1.1 1e-52 178.6 1.1 3.6 3 1 1 4 4 4 2 Diaphanous FH3 Domain 2-Hacid_dh_C PF02826.19 ORY07153.1 - 2.3e-50 170.4 0.0 5.6e-50 169.2 0.0 1.6 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 ORY07153.1 - 2.3e-14 53.2 0.0 4.1e-14 52.4 0.0 1.5 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 ORY07153.1 - 0.00088 19.5 0.0 0.002 18.3 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase BTB PF00651.31 ORY07154.1 - 0.005 17.1 0.0 0.0083 16.3 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Aldedh PF00171.22 ORY07155.1 - 4.7e-156 519.9 0.3 5.2e-156 519.7 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 ORY07155.1 - 0.086 11.9 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) Cutinase PF01083.22 ORY07157.1 - 4.2e-29 101.7 3.2 6.5e-29 101.1 3.2 1.3 1 0 0 1 1 1 1 Cutinase MatE PF01554.18 ORY07158.1 - 1.3e-10 41.1 17.6 1.9e-05 24.4 2.6 3.5 3 0 0 3 3 3 3 MatE Polysacc_synt_C PF14667.6 ORY07158.1 - 0.00043 20.4 0.3 0.00043 20.4 0.3 3.9 5 1 0 5 5 5 1 Polysaccharide biosynthesis C-terminal domain DUF2628 PF10947.8 ORY07158.1 - 0.22 11.9 0.1 0.22 11.9 0.1 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF2628) SCIMP PF15050.6 ORY07159.1 - 0.019 15.4 0.0 0.03 14.8 0.0 1.4 1 0 0 1 1 1 0 SCIMP protein FAM163 PF15069.6 ORY07159.1 - 0.072 13.5 0.0 0.1 13.1 0.0 1.3 1 0 0 1 1 1 0 FAM163 family CN_hydrolase PF00795.22 ORY07160.1 - 2.1e-47 161.7 0.0 2.4e-47 161.5 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Nmad3 PF18754.1 ORY07160.1 - 0.0062 16.1 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 Nucleotide modification associated domain 3 rpo132 PF12415.8 ORY07160.1 - 0.04 13.2 0.1 0.085 12.2 0.1 1.5 1 0 0 1 1 1 0 Poxvirus DNA dependent RNA polymerase RL11D PF11088.8 ORY07160.1 - 0.067 13.5 0.0 0.43 10.9 0.0 2.1 1 1 0 2 2 2 0 Glycoprotein encoding membrane proteins RL5A and RL6 Use1 PF09753.9 ORY07161.1 - 0.0077 16.0 0.0 0.0089 15.8 0.0 1.2 1 1 0 1 1 1 1 Membrane fusion protein Use1 RAP1 PF07218.11 ORY07161.1 - 0.083 11.2 0.6 0.097 10.9 0.6 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) RNA12 PF10443.9 ORY07162.1 - 1.4e-172 574.5 0.0 2.1e-172 573.9 0.0 1.3 1 0 0 1 1 1 1 RNA12 protein RRM_1 PF00076.22 ORY07162.1 - 0.0032 17.2 0.0 0.0092 15.8 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2487 PF10673.9 ORY07162.1 - 0.0042 17.1 0.0 0.011 15.8 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2487) ATPase_2 PF01637.18 ORY07162.1 - 0.0049 16.8 0.0 0.045 13.7 0.0 2.2 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea GATase_2 PF00310.21 ORY07163.1 - 2.1e-178 593.3 0.0 2.9e-178 592.9 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 ORY07163.1 - 7.2e-156 518.9 0.0 2.3e-155 517.3 0.0 1.8 2 0 0 2 2 2 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 ORY07163.1 - 1.7e-112 375.5 0.0 2.3e-110 368.5 0.0 2.2 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.19 ORY07163.1 - 3.3e-86 287.7 1.5 5.6e-86 287.0 1.5 1.4 1 0 0 1 1 1 1 GXGXG motif Pyr_redox_2 PF07992.14 ORY07163.1 - 1.8e-23 83.2 0.1 1.2e-22 80.5 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 ORY07163.1 - 6.6e-21 74.2 0.1 1.3e-20 73.2 0.1 1.5 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster NAD_binding_8 PF13450.6 ORY07163.1 - 1.9e-08 34.4 0.0 7e-08 32.6 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ORY07163.1 - 1.2e-07 31.7 1.8 0.00056 19.6 0.6 2.6 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 ORY07163.1 - 1.4e-06 28.7 0.8 0.0002 21.8 0.2 2.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ORY07163.1 - 1.6e-06 27.6 0.2 0.0073 15.6 0.0 3.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 ORY07163.1 - 1.3e-05 24.7 0.1 2.6e-05 23.7 0.1 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase HI0933_like PF03486.14 ORY07163.1 - 2.9e-05 22.9 0.2 2.9e-05 22.9 0.2 1.7 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 ORY07163.1 - 0.0003 20.0 2.5 0.00065 18.9 0.3 2.6 3 0 0 3 3 3 1 FAD binding domain AdoHcyase_NAD PF00670.21 ORY07163.1 - 0.00036 20.6 0.6 0.31 11.1 0.1 2.7 2 0 0 2 2 2 2 S-adenosyl-L-homocysteine hydrolase, NAD binding domain FAD_oxidored PF12831.7 ORY07163.1 - 0.0011 18.4 0.2 0.0011 18.4 0.2 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 ORY07163.1 - 0.0016 17.6 0.3 0.31 10.0 0.1 2.5 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.17 ORY07163.1 - 0.0018 17.5 1.2 0.006 15.8 0.1 2.3 3 0 0 3 3 3 1 Thi4 family MADF_DNA_bdg PF10545.9 ORY07163.1 - 0.0031 17.8 0.3 0.0075 16.6 0.3 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like FAD_binding_3 PF01494.19 ORY07163.1 - 0.0079 15.5 0.0 0.017 14.4 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain NAD_binding_7 PF13241.6 ORY07163.1 - 0.024 15.1 2.0 1.4 9.4 0.1 2.7 2 0 0 2 2 2 0 Putative NAD(P)-binding FMO-like PF00743.19 ORY07163.1 - 0.036 12.5 0.2 7.7 4.8 0.0 2.6 2 1 0 3 3 3 0 Flavin-binding monooxygenase-like FMN_dh PF01070.18 ORY07163.1 - 0.046 12.7 0.4 0.18 10.8 0.5 1.8 2 0 0 2 2 2 0 FMN-dependent dehydrogenase 2-Hacid_dh_C PF02826.19 ORY07163.1 - 0.2 11.0 0.1 0.92 8.8 0.0 2.0 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 ORY07163.1 - 0.21 10.8 0.4 9.6 5.4 0.0 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 ORY07163.1 - 0.9 8.5 4.6 0.24 10.5 0.2 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A CHZ PF09649.10 ORY07165.1 - 4.8e-21 73.9 3.4 1.8e-20 72.1 3.4 2.1 1 0 0 1 1 1 1 Histone chaperone domain CHZ Spt46 PF17734.1 ORY07165.1 - 0.11 12.2 1.0 0.14 11.9 1.0 1.0 1 0 0 1 1 1 0 Spermatogenesis-associated protein 46 HNF-1_N PF04814.13 ORY07165.1 - 0.88 10.2 4.3 0.95 10.0 4.3 1.0 1 0 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus Mcl1_mid PF12341.8 ORY07166.1 - 1.9e-102 342.6 0.3 2.3e-99 332.5 0.0 3.1 2 1 1 3 3 3 1 Minichromosome loss protein, Mcl1, middle region ANAPC4_WD40 PF12894.7 ORY07166.1 - 7.2e-15 55.1 0.1 0.00028 21.1 0.0 6.1 2 1 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 ORY07166.1 - 7.8e-15 55.0 6.8 6.3e-05 23.7 0.1 7.4 9 0 0 9 9 7 3 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 ORY07166.1 - 1.4e-06 27.6 0.1 0.0044 16.1 0.0 2.2 1 1 1 2 2 2 2 Coatomer WD associated region Ge1_WD40 PF16529.5 ORY07166.1 - 0.00032 19.8 0.2 5.2 5.9 0.0 3.2 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 ORY07166.1 - 0.01 15.2 0.6 0.74 9.1 0.1 2.7 2 1 0 3 3 3 0 WD40-like domain Frtz PF11768.8 ORY07166.1 - 0.012 14.0 0.0 0.61 8.3 0.0 2.8 2 1 1 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz PD40 PF07676.12 ORY07166.1 - 0.025 14.5 2.4 20 5.3 0.0 4.4 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat eIF2A PF08662.11 ORY07166.1 - 0.045 13.6 0.0 0.62 9.9 0.0 2.6 1 1 2 3 3 3 0 Eukaryotic translation initiation factor eIF2A DNA_pol_alpha_N PF12254.8 ORY07166.1 - 0.051 13.7 1.7 0.13 12.4 1.7 1.6 1 0 0 1 1 1 0 DNA polymerase alpha subunit p180 N terminal WD40_3 PF15911.5 ORY07166.1 - 0.054 13.5 0.5 4.9 7.2 0.0 3.6 4 0 0 4 4 4 0 WD domain, G-beta repeat TFIIIC_delta PF12657.7 ORY07166.1 - 0.065 13.2 0.2 0.17 11.8 0.2 1.7 1 0 0 1 1 1 0 Transcription factor IIIC subunit delta N-term PSII_BNR PF14870.6 ORY07166.1 - 0.13 11.5 0.0 0.53 9.5 0.0 1.9 2 0 0 2 2 2 0 Photosynthesis system II assembly factor YCF48 PQQ_3 PF13570.6 ORY07166.1 - 0.14 12.7 0.7 28 5.4 0.0 3.9 3 0 0 3 3 3 0 PQQ-like domain Tubulin PF00091.25 ORY07167.1 - 2.6e-66 223.6 0.0 4.1e-66 223.0 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 ORY07167.1 - 3.2e-50 169.5 0.1 5.9e-50 168.7 0.1 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 ORY07167.1 - 0.0046 16.7 0.0 0.01 15.5 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain Pga1 PF10333.9 ORY07168.1 - 1.2e-05 25.2 0.0 2.6e-05 24.1 0.0 1.5 2 0 0 2 2 2 1 GPI-Mannosyltransferase II co-activator RNA_pol_Rpb2_6 PF00562.28 ORY07170.1 - 7.1e-126 420.4 0.2 1.2e-125 419.6 0.2 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 ORY07170.1 - 1.9e-55 187.5 0.5 2.8e-55 187.0 0.5 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 ORY07170.1 - 4.1e-33 113.6 1.2 1.1e-32 112.3 1.2 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 ORY07170.1 - 4.9e-30 104.6 0.3 1e-29 103.6 0.3 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.13 ORY07170.1 - 3.2e-23 81.8 0.0 7.8e-23 80.5 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 ORY07170.1 - 2.8e-18 65.9 0.0 7.7e-18 64.4 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 ORY07170.1 - 1.3e-10 41.6 0.0 3.7e-10 40.2 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 DUF382 PF04037.13 ORY07172.1 - 1.1e-57 193.6 0.4 3.8e-57 191.9 0.4 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF382) PSP PF04046.16 ORY07172.1 - 2e-18 66.0 1.8 2e-18 66.0 1.8 2.1 3 0 0 3 3 3 1 PSP HD_2 PF12917.7 ORY07172.1 - 0.091 12.5 0.4 0.19 11.5 0.4 1.4 1 0 0 1 1 1 0 HD containing hydrolase-like enzyme BSP_II PF05432.11 ORY07172.1 - 1.1 8.9 15.2 0.031 14.0 8.7 1.7 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) Aldo_ket_red PF00248.21 ORY07173.1 - 2.3e-45 155.1 0.1 2.4e-44 151.7 0.1 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family E1-E2_ATPase PF00122.20 ORY07174.1 - 9.3e-49 165.4 5.8 9.3e-49 165.4 5.8 2.7 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 ORY07174.1 - 8.2e-17 62.2 0.0 2.9e-16 60.4 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 ORY07174.1 - 5.9e-11 41.9 0.0 1.3e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 ORY07174.1 - 0.0025 17.6 0.1 0.005 16.6 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 ORY07174.1 - 0.0099 15.9 0.0 0.021 14.9 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) HTH_ABP1_N PF18107.1 ORY07175.1 - 0.06 13.1 0.9 0.12 12.1 0.1 2.0 2 0 0 2 2 2 0 Fission yeast centromere protein N-terminal domain RNA_pol_Rpb1_2 PF00623.20 ORY07249.1 - 2.6e-68 229.4 0.3 5.3e-68 228.5 0.3 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 ORY07249.1 - 4.6e-32 111.1 0.0 8.7e-32 110.2 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.12 ORY07249.1 - 1.8e-27 96.5 2.8 4e-25 88.8 1.1 3.3 2 1 0 2 2 2 2 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 ORY07249.1 - 7.6e-27 94.4 0.1 7.6e-27 94.4 0.1 2.3 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_4 PF05000.17 ORY07249.1 - 3e-19 68.9 0.4 1.4e-18 66.8 0.0 2.4 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 DUF4885 PF16226.5 ORY07249.1 - 0.2 10.7 1.8 0.34 9.9 0.4 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4885) PRP3 PF08572.10 ORY07250.1 - 3e-67 226.6 7.8 5.4e-67 225.8 7.8 1.4 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 ORY07250.1 - 2.5e-40 137.9 0.1 2.5e-40 137.9 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) Abhydrolase_6 PF12697.7 ORY07251.1 - 1.5e-16 61.7 0.0 1.7e-16 61.5 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.7 ORY07251.1 - 0.0093 14.9 0.0 0.019 13.9 0.0 1.5 2 0 0 2 2 2 1 Chlorophyllase enzyme Abhydrolase_1 PF00561.20 ORY07251.1 - 0.011 15.3 0.2 0.028 14.1 0.1 1.7 2 1 1 3 3 3 0 alpha/beta hydrolase fold Thioredoxin PF00085.20 ORY07252.1 - 1e-20 73.7 0.0 1.2e-20 73.4 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 ORY07252.1 - 2e-06 28.2 0.3 7.7e-06 26.3 0.3 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 ORY07252.1 - 6.9e-05 22.6 0.0 7.6e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_3 PF13192.6 ORY07252.1 - 0.00089 19.3 0.0 0.0012 18.9 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin domain OST3_OST6 PF04756.13 ORY07252.1 - 0.00093 18.6 0.0 0.0011 18.4 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 ORY07252.1 - 0.0016 18.4 0.1 0.0024 17.8 0.1 1.4 1 1 0 1 1 1 1 AhpC/TSA family HyaE PF07449.11 ORY07252.1 - 0.0053 16.7 0.0 0.0065 16.4 0.0 1.2 1 0 0 1 1 1 1 Hydrogenase-1 expression protein HyaE Thioredoxin_8 PF13905.6 ORY07252.1 - 0.0062 16.8 0.0 0.45 10.9 0.0 2.2 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_5 PF13743.6 ORY07252.1 - 0.021 14.5 0.1 0.18 11.5 0.0 2.0 1 1 1 2 2 2 0 Thioredoxin DUF953 PF06110.11 ORY07252.1 - 0.055 13.1 0.0 0.065 12.9 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) Glutaredoxin PF00462.24 ORY07252.1 - 0.074 13.3 0.2 0.17 12.1 0.2 1.7 1 1 0 1 1 1 0 Glutaredoxin Thioredoxin_4 PF13462.6 ORY07252.1 - 0.11 12.6 0.2 5.9 7.0 0.0 2.1 1 1 1 2 2 2 0 Thioredoxin HET PF06985.11 ORY07253.1 - 7.8e-20 71.7 0.0 9.7e-20 71.4 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Rad50_zn_hook PF04423.14 ORY07254.1 - 0.054 13.3 0.2 0.088 12.7 0.2 1.3 1 0 0 1 1 1 0 Rad50 zinc hook motif MARVEL PF01284.23 ORY07255.1 - 3.8e-18 65.9 10.9 5e-18 65.5 10.9 1.1 1 0 0 1 1 1 1 Membrane-associating domain HALZ PF02183.18 ORY07256.1 - 2.5e-06 27.6 8.8 0.00073 19.7 1.0 3.6 3 0 0 3 3 3 2 Homeobox associated leucine zipper BRE1 PF08647.11 ORY07256.1 - 0.00012 22.1 22.8 0.033 14.2 9.3 2.6 2 0 0 2 2 2 2 BRE1 E3 ubiquitin ligase Macoilin PF09726.9 ORY07256.1 - 0.00012 20.8 13.6 0.00017 20.3 13.6 1.2 1 0 0 1 1 1 1 Macoilin family CENP-F_leu_zip PF10473.9 ORY07256.1 - 0.00042 20.4 25.0 0.0016 18.5 9.9 2.6 2 1 0 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CALCOCO1 PF07888.11 ORY07256.1 - 0.0012 17.8 15.7 0.0012 17.8 15.7 2.2 1 1 1 2 2 2 1 Calcium binding and coiled-coil domain (CALCOCO1) like DUF3450 PF11932.8 ORY07256.1 - 0.0051 16.1 12.7 0.38 10.0 4.7 2.7 1 1 1 2 2 2 2 Protein of unknown function (DUF3450) DUF1664 PF07889.12 ORY07256.1 - 0.0069 16.4 10.5 0.075 13.1 1.5 3.0 2 2 1 3 3 3 1 Protein of unknown function (DUF1664) Atg14 PF10186.9 ORY07256.1 - 0.0072 15.5 26.2 0.18 10.9 6.7 2.1 1 1 1 2 2 2 2 Vacuolar sorting 38 and autophagy-related subunit 14 Golgin_A5 PF09787.9 ORY07256.1 - 0.0072 15.8 19.5 0.013 15.0 19.5 1.4 1 0 0 1 1 1 1 Golgin subfamily A member 5 DUF16 PF01519.16 ORY07256.1 - 0.0084 16.6 13.1 0.0099 16.4 2.1 2.6 1 1 1 2 2 2 1 Protein of unknown function DUF16 FapA PF03961.13 ORY07256.1 - 0.032 12.8 11.9 0.048 12.3 11.9 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A PBP-Tp47_a PF14889.6 ORY07256.1 - 0.033 13.8 0.0 0.079 12.6 0.0 1.6 1 0 0 1 1 1 0 Penicillin-binding protein Tp47 domain a FAP206 PF12018.8 ORY07256.1 - 0.055 13.0 4.8 0.059 12.9 3.5 1.6 1 1 1 2 2 2 0 Domain of unknown function Phage_GP20 PF06810.11 ORY07256.1 - 0.059 13.2 17.4 0.14 12.0 2.3 2.7 1 1 0 2 2 2 0 Phage minor structural protein GP20 ADIP PF11559.8 ORY07256.1 - 0.094 12.8 23.3 2.7 8.1 9.9 2.8 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding AAA_13 PF13166.6 ORY07256.1 - 0.1 11.2 16.1 0.14 10.8 16.1 1.1 1 0 0 1 1 1 0 AAA domain FlaC_arch PF05377.11 ORY07256.1 - 0.15 12.5 6.9 6.5 7.2 0.4 3.5 2 2 1 3 3 3 0 Flagella accessory protein C (FlaC) Rho_Binding PF08912.11 ORY07256.1 - 0.22 12.4 12.6 0.99 10.3 0.3 3.4 2 1 0 2 2 2 0 Rho Binding Spc7 PF08317.11 ORY07256.1 - 0.22 10.4 21.8 0.047 12.6 16.8 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein KASH_CCD PF14662.6 ORY07256.1 - 0.27 11.0 24.4 0.28 11.0 22.6 1.9 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH DivIVA PF05103.13 ORY07256.1 - 0.43 10.7 15.8 0.87 9.7 1.3 2.5 1 1 1 2 2 2 0 DivIVA protein DUF5082 PF16888.5 ORY07256.1 - 0.46 10.8 14.0 1 9.7 14.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) APG6_N PF17675.1 ORY07256.1 - 0.48 10.9 27.9 1.2 9.7 8.9 2.9 1 1 2 3 3 3 0 Apg6 coiled-coil region Jnk-SapK_ap_N PF09744.9 ORY07256.1 - 0.68 10.2 24.4 6 7.1 11.0 2.7 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 TPR_MLP1_2 PF07926.12 ORY07256.1 - 0.82 9.7 23.6 0.16 12.1 13.1 3.0 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DMPK_coil PF08826.10 ORY07256.1 - 0.93 9.6 11.1 0.77 9.9 1.7 3.2 3 1 0 3 3 2 0 DMPK coiled coil domain like CENP-Q PF13094.6 ORY07256.1 - 1.2 9.3 19.4 3.2 7.9 7.8 2.3 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit GAS PF13851.6 ORY07256.1 - 1.3 8.4 28.1 0.76 9.1 9.8 2.6 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF2703 PF10865.8 ORY07256.1 - 1.3 9.2 6.5 7.9 6.7 0.9 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF2703) Filament PF00038.21 ORY07256.1 - 1.5 8.3 23.7 4.6 6.7 0.6 2.8 1 1 2 3 3 3 0 Intermediate filament protein TMPIT PF07851.13 ORY07256.1 - 1.9 7.6 17.3 0.38 9.9 6.0 2.2 1 1 1 2 2 2 0 TMPIT-like protein ATG16 PF08614.11 ORY07256.1 - 2 8.6 20.2 1.9 8.6 9.2 2.4 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) BLOC1_2 PF10046.9 ORY07256.1 - 2.3 8.6 10.8 12 6.2 1.0 2.6 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 PI3K_P85_iSH2 PF16454.5 ORY07256.1 - 2.6 7.6 17.8 2 8.0 15.6 1.9 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Prefoldin_2 PF01920.20 ORY07256.1 - 3.7 7.6 21.0 19 5.2 12.2 3.4 1 1 1 2 2 2 0 Prefoldin subunit Ly49 PF08391.10 ORY07256.1 - 3.8 7.9 10.4 1.4 9.3 7.2 2.0 1 1 1 2 2 2 0 Ly49-like protein, N-terminal region DUF4140 PF13600.6 ORY07256.1 - 3.9 8.0 12.0 17 6.0 1.1 3.4 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF641 PF04859.12 ORY07256.1 - 4.2 7.7 14.1 13 6.1 4.6 2.5 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) PspB PF06667.12 ORY07256.1 - 4.4 7.4 6.9 1.5 8.9 1.0 2.9 2 1 1 3 3 3 0 Phage shock protein B Tropomyosin_1 PF12718.7 ORY07256.1 - 5.2 7.2 29.3 1.4 9.0 20.8 2.7 2 1 1 3 3 2 0 Tropomyosin like DivIC PF04977.15 ORY07256.1 - 5.2 6.9 16.7 2.2 8.1 0.3 3.6 2 1 2 4 4 3 0 Septum formation initiator DUF2203 PF09969.9 ORY07256.1 - 5.4 7.8 12.2 2.8 8.7 1.8 2.7 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) ERM PF00769.19 ORY07256.1 - 5.6 6.7 27.7 0.82 9.4 10.3 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family JIP_LZII PF16471.5 ORY07256.1 - 6.4 7.0 14.5 0.92 9.7 2.9 3.2 3 0 0 3 3 2 0 JNK-interacting protein leucine zipper II Fib_alpha PF08702.10 ORY07256.1 - 7.1 6.8 17.1 1.6 8.9 11.1 2.8 2 1 1 3 3 2 0 Fibrinogen alpha/beta chain family UPF0242 PF06785.11 ORY07256.1 - 7.1 6.7 23.6 2.6 8.1 6.1 2.3 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus HIP1_clath_bdg PF16515.5 ORY07256.1 - 8.7 7.0 19.6 16 6.2 7.8 2.9 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 PEARLI-4 PF05278.12 ORY07256.1 - 9 5.8 17.3 0.1 12.2 5.2 2.2 1 1 1 2 2 2 0 Arabidopsis phospholipase-like protein (PEARLI 4) Prefoldin PF02996.17 ORY07256.1 - 9 6.2 13.0 0.58 10.1 1.7 3.3 2 1 1 3 3 3 0 Prefoldin subunit TMF_DNA_bd PF12329.8 ORY07256.1 - 9.7 6.3 21.3 0.63 10.1 3.3 2.9 1 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding HSP70 PF00012.20 ORY07257.1 - 1.7e-12 46.4 0.0 3e-11 42.2 0.0 2.2 2 1 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 ORY07257.1 - 0.0091 14.9 0.1 0.073 11.9 0.1 2.0 2 0 0 2 2 2 1 MreB/Mbl protein Ribosomal_L27e PF01777.18 ORY07259.1 - 3.4e-36 123.4 7.3 4.7e-36 123.0 7.3 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 ORY07259.1 - 0.00012 21.8 0.2 0.00035 20.4 0.2 1.7 1 0 0 1 1 1 1 KOW motif WD40 PF00400.32 ORY07260.1 - 5.7e-34 115.6 3.6 1.5e-07 32.0 0.0 6.4 6 0 0 6 6 6 4 WD domain, G-beta repeat Sof1 PF04158.14 ORY07260.1 - 3.2e-30 104.2 20.9 6.5e-30 103.2 20.9 1.5 1 0 0 1 1 1 1 Sof1-like domain ANAPC4_WD40 PF12894.7 ORY07260.1 - 3.7e-12 46.4 0.1 0.032 14.5 0.0 4.5 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 ORY07260.1 - 3.6e-06 25.6 0.0 0.0027 16.1 0.0 2.3 1 1 1 2 2 2 2 WD repeat-containing and planar cell polarity effector protein Fritz BBS2_Mid PF14783.6 ORY07260.1 - 0.0017 18.4 0.0 11 6.1 0.0 4.5 2 2 3 5 5 5 1 Ciliary BBSome complex subunit 2, middle region PALB2_WD40 PF16756.5 ORY07260.1 - 0.048 12.6 0.0 0.71 8.7 0.0 2.1 1 1 0 1 1 1 0 Partner and localizer of BRCA2 WD40 domain MFS_1 PF07690.16 ORY07261.1 - 4.6e-44 150.8 36.4 9.7e-44 149.7 29.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 ORY07261.1 - 1.3e-10 40.4 3.4 1.3e-10 40.4 3.4 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 ORY07261.1 - 7.4e-07 28.4 26.5 3.7e-06 26.1 26.5 2.5 1 1 0 1 1 1 1 Sugar (and other) transporter RRM_1 PF00076.22 ORY07262.1 - 2.1e-53 178.0 0.0 7.8e-18 64.1 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 ORY07262.1 - 1.3e-05 24.7 0.0 0.0058 16.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 ORY07262.1 - 0.00055 20.0 0.4 7.2 6.8 0.0 4.2 3 2 0 3 3 3 2 Limkain b1 RRM_occluded PF16842.5 ORY07262.1 - 0.0022 17.8 0.0 10 6.0 0.0 3.2 3 0 0 3 3 3 2 Occluded RNA-recognition motif THRAP3_BCLAF1 PF15440.6 ORY07262.1 - 0.015 14.4 21.3 0.02 14.0 21.3 1.1 1 0 0 1 1 1 0 THRAP3/BCLAF1 family PknH_C PF14032.6 ORY07262.1 - 0.028 14.3 0.5 6.8 6.5 0.1 3.1 3 0 0 3 3 3 0 PknH-like extracellular domain ATP-grasp_2 PF08442.10 ORY07262.1 - 0.041 13.4 0.0 2.1 7.9 0.0 2.7 3 0 0 3 3 3 0 ATP-grasp domain RRM_9 PF18444.1 ORY07262.1 - 0.08 12.8 0.0 11 6.0 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif SPOR PF05036.13 ORY07262.1 - 0.096 13.1 0.1 57 4.2 0.0 3.3 3 0 0 3 3 3 0 Sporulation related domain YoaP PF14268.6 ORY07262.1 - 0.4 10.2 1.7 2.5 7.7 0.0 2.7 3 0 0 3 3 3 0 YoaP-like Mito_carr PF00153.27 ORY07263.1 - 1.4e-48 162.7 0.5 3.1e-19 68.7 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein PAP2_3 PF14378.6 ORY07265.1 - 6.7e-24 84.6 16.2 6.7e-24 84.6 16.2 2.0 1 1 1 2 2 2 1 PAP2 superfamily PAP2 PF01569.21 ORY07265.1 - 1.3e-06 28.3 5.3 1.3e-06 28.3 5.3 2.3 2 1 0 2 2 2 1 PAP2 superfamily Pyr_redox_2 PF07992.14 ORY07266.1 - 1.5e-52 178.7 0.6 1.9e-52 178.4 0.6 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORY07266.1 - 1.4e-21 76.9 0.1 6.7e-17 61.8 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 ORY07266.1 - 7.6e-16 58.3 0.0 1.9e-15 57.1 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_3 PF13738.6 ORY07266.1 - 3.5e-09 36.3 0.0 1.6e-06 27.6 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORY07266.1 - 0.00032 20.9 0.3 0.28 11.5 0.1 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 ORY07266.1 - 0.00066 19.0 0.6 0.03 13.6 0.1 2.3 2 0 0 2 2 2 1 FAD binding domain K_oxygenase PF13434.6 ORY07266.1 - 0.00066 18.9 0.0 0.17 11.0 0.0 2.9 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.22 ORY07266.1 - 0.0011 18.1 1.1 0.47 9.5 0.9 2.5 3 0 0 3 3 3 2 Glucose inhibited division protein A XdhC_C PF13478.6 ORY07266.1 - 0.0057 17.2 0.0 2.1 8.9 0.0 2.3 2 0 0 2 2 2 1 XdhC Rossmann domain 3HCDH_N PF02737.18 ORY07266.1 - 0.0063 16.4 0.1 0.71 9.7 0.0 2.3 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 ORY07266.1 - 0.011 15.8 0.0 7.9 6.4 0.0 3.0 3 0 0 3 3 3 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus AlaDh_PNT_C PF01262.21 ORY07266.1 - 0.011 15.0 0.0 0.081 12.2 0.0 2.1 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 ORY07266.1 - 0.012 14.3 0.2 5.2 5.7 0.0 2.9 2 1 1 3 3 3 0 HI0933-like protein 2-Hacid_dh_C PF02826.19 ORY07266.1 - 0.017 14.5 0.0 1.6 8.1 0.0 2.4 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 ORY07266.1 - 0.032 13.3 0.2 1 8.3 0.1 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein DAO PF01266.24 ORY07266.1 - 0.06 12.9 6.0 0.62 9.6 0.1 3.1 2 1 1 3 3 3 0 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.14 ORY07266.1 - 0.12 11.9 0.5 2.6 7.6 0.0 2.4 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.18 ORY07266.1 - 0.14 12.5 0.1 11 6.3 0.0 2.7 2 0 0 2 2 2 0 TrkA-N domain FAD_oxidored PF12831.7 ORY07266.1 - 0.15 11.4 0.6 1.1 8.6 0.3 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase Vps62 PF06101.11 ORY07268.1 - 4.5e-06 25.3 0.5 6.9e-06 24.6 0.5 1.3 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 62 DUF1302 PF06980.11 ORY07268.1 - 0.12 11.0 1.0 0.19 10.3 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1302) TFIIIC_sub6 PF10419.9 ORY07269.1 - 1.3e-22 79.5 0.0 2e-22 78.9 0.0 1.3 1 0 0 1 1 1 1 TFIIIC subunit triple barrel domain Redoxin PF08534.10 ORY07271.1 - 2.4e-25 89.0 0.0 2.8e-25 88.7 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 ORY07271.1 - 3.1e-06 27.1 0.0 3.8e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family HSF_DNA-bind PF00447.17 ORY07273.1 - 3e-31 107.9 2.4 6.9e-31 106.7 2.4 1.6 1 0 0 1 1 1 1 HSF-type DNA-binding Response_reg PF00072.24 ORY07273.1 - 1.6e-23 83.0 0.0 3.3e-23 82.0 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain W2 PF02020.18 ORY07274.1 - 9.4e-13 48.1 2.4 3.1e-12 46.4 2.4 1.9 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.24 ORY07274.1 - 2.9e-10 39.5 15.9 3.3e-05 23.4 8.9 4.0 3 1 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.23 ORY07274.1 - 1.3e-08 34.7 0.0 2.4e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 ORY07274.1 - 3.2e-05 24.4 0.0 7.7e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 ORY07274.1 - 0.00037 20.2 9.4 0.23 11.2 0.7 3.6 2 1 1 3 3 3 2 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 ORY07274.1 - 0.028 12.6 0.8 0.06 11.5 0.5 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4954) Fucokinase PF07959.12 ORY07274.1 - 0.049 12.6 0.7 0.46 9.4 0.7 2.2 1 1 0 1 1 1 0 L-fucokinase DUF5505 PF17610.2 ORY07274.1 - 0.16 12.0 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5505) IBR PF01485.21 ORY07276.1 - 3.8e-24 84.7 45.8 9.2e-14 51.4 5.2 4.5 3 1 1 4 4 4 3 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 ORY07276.1 - 1.7e-05 24.6 40.5 4.1e-05 23.3 4.1 4.7 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORY07276.1 - 3.5e-05 24.0 3.8 3.5e-05 24.0 3.8 4.2 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.6 ORY07276.1 - 0.003 17.4 5.9 0.003 17.4 5.9 5.1 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORY07276.1 - 0.0037 17.3 5.0 0.0037 17.3 5.0 4.0 3 1 0 3 3 3 2 RING-type zinc-finger zf-RING_5 PF14634.6 ORY07276.1 - 0.013 15.4 7.2 0.013 15.4 7.2 4.0 2 1 1 3 3 3 0 zinc-RING finger domain Helicase_IV_N PF12462.8 ORY07276.1 - 0.043 13.7 11.7 5 7.0 0.0 2.6 2 1 0 2 2 2 0 DNA helicase IV / RNA helicase N terminal Trp_syntA PF00290.20 ORY07276.1 - 0.066 12.1 0.0 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 Tryptophan synthase alpha chain zf-C3HC4_4 PF15227.6 ORY07276.1 - 0.077 13.2 26.0 0.12 12.5 0.3 4.6 3 1 0 3 3 3 0 zinc finger of C3HC4-type, RING Con-6 PF10346.9 ORY07277.1 - 1.1e-14 54.1 2.9 1.9e-14 53.4 2.9 1.4 1 0 0 1 1 1 1 Conidiation protein 6 Amidohydro_2 PF04909.14 ORY07278.1 - 8.7e-05 22.4 0.0 0.00013 21.9 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.20 ORY07278.1 - 0.00029 20.3 0.0 0.0018 17.7 0.0 2.2 1 1 0 1 1 1 1 Amidohydrolase family DNA_methylase PF00145.17 ORY07279.1 - 2.9e-30 105.8 0.0 5.5e-30 104.9 0.0 1.4 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase DUF3431 PF11913.8 ORY07280.1 - 7e-85 284.2 0.4 9e-85 283.8 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) FmdA_AmdA PF03069.15 ORY07281.1 - 4.1e-178 591.9 0.0 5.3e-178 591.6 0.0 1.1 1 0 0 1 1 1 1 Acetamidase/Formamidase family EI24 PF07264.11 ORY07281.1 - 4.5e-14 53.1 0.7 8e-12 45.8 0.7 2.2 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Inp1 PF12634.7 ORY07282.1 - 3.6e-33 114.5 1.0 4.1e-32 111.1 1.0 2.1 1 1 0 1 1 1 1 Inheritance of peroxisomes protein 1 Pkinase PF00069.25 ORY07284.1 - 5.7e-18 65.2 0.1 6.5e-18 65.0 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY07284.1 - 7.8e-09 35.2 0.0 9.7e-09 34.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 ORY07284.1 - 0.063 12.9 0.2 1.3 8.6 0.1 2.1 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pro_CA PF00484.19 ORY07285.1 - 8.8e-08 32.6 0.0 1.7e-07 31.6 0.0 1.5 1 1 0 1 1 1 1 Carbonic anhydrase SKA1 PF07160.12 ORY07286.1 - 0.15 11.9 0.4 4.1 7.2 0.0 2.1 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 CFEM PF05730.11 ORY07288.1 - 1.4e-08 34.7 4.0 2.2e-08 34.1 4.0 1.3 1 0 0 1 1 1 1 CFEM domain Gamma-thionin PF00304.20 ORY07288.1 - 0.09 13.1 1.5 0.17 12.2 1.5 1.4 1 0 0 1 1 1 0 Gamma-thionin family Herpes_gE PF02480.16 ORY07289.1 - 0.23 10.2 0.5 1.1 8.0 0.0 1.9 1 1 1 2 2 2 0 Alphaherpesvirus glycoprotein E CFEM PF05730.11 ORY07290.1 - 0.00044 20.3 2.8 0.00065 19.7 2.8 1.3 1 0 0 1 1 1 1 CFEM domain Amino_oxidase PF01593.24 ORY07291.1 - 3.3e-18 66.2 0.0 4.9e-17 62.4 0.0 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 ORY07291.1 - 3.5e-10 40.0 0.0 4.1e-09 36.5 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ORY07291.1 - 0.00045 19.9 0.1 0.0031 17.2 0.0 2.1 2 1 0 2 2 2 1 FAD dependent oxidoreductase MCRA PF06100.11 ORY07291.1 - 0.03 13.1 0.0 0.056 12.2 0.0 1.3 1 0 0 1 1 1 0 MCRA family Thi4 PF01946.17 ORY07291.1 - 0.13 11.5 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Thi4 family zf-CCCH_2 PF14608.6 ORY07292.1 - 5.1e-10 39.5 53.0 0.0048 17.3 4.7 5.4 5 0 0 5 5 5 5 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 ORY07292.1 - 0.15 12.3 16.0 6.1 7.1 9.8 3.5 2 2 1 3 3 3 0 Zinc-finger containing family RRM_1 PF00076.22 ORY07293.1 - 2.5e-11 43.2 0.0 3.6e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 ORY07293.1 - 0.00095 19.1 0.0 0.0013 18.6 0.0 1.2 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif MARVEL PF01284.23 ORY07295.1 - 1.4e-07 31.7 10.0 2e-07 31.2 10.0 1.2 1 0 0 1 1 1 1 Membrane-associating domain DUF2427 PF10348.9 ORY07295.1 - 0.0001 22.0 1.6 0.00011 21.9 0.9 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF2427) FA_desaturase PF00487.24 ORY07295.1 - 0.00046 20.1 2.9 0.00053 19.9 2.9 1.1 1 0 0 1 1 1 1 Fatty acid desaturase Granulin PF00396.18 ORY07297.1 - 4.3 7.8 20.5 6.9 7.1 4.2 2.6 2 0 0 2 2 2 0 Granulin DUF3176 PF11374.8 ORY07298.1 - 1.4e-30 105.6 1.7 2.5e-30 104.8 1.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) CCDC92 PF14916.6 ORY07302.1 - 0.0027 17.5 3.9 0.0047 16.7 1.8 2.1 1 1 1 2 2 2 1 Coiled-coil domain of unknown function FAM76 PF16046.5 ORY07302.1 - 0.0072 15.7 2.7 0.0088 15.4 2.7 1.1 1 0 0 1 1 1 1 FAM76 protein ExsD PF16806.5 ORY07302.1 - 0.011 15.6 4.6 0.011 15.6 4.6 1.5 1 1 1 2 2 2 0 Antiactivator protein ExsD DUF2524 PF10732.9 ORY07302.1 - 0.047 14.0 1.5 0.12 12.7 1.3 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2524) DUF4972 PF16342.5 ORY07302.1 - 0.059 13.1 2.8 0.11 12.2 2.4 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4972) TSC22 PF01166.18 ORY07302.1 - 0.06 13.7 5.3 2.9 8.3 0.2 2.6 2 1 1 3 3 3 0 TSC-22/dip/bun family PAC2 PF09754.9 ORY07302.1 - 0.073 13.1 0.0 0.096 12.7 0.0 1.2 1 0 0 1 1 1 0 PAC2 family BRE1 PF08647.11 ORY07302.1 - 0.14 12.2 10.5 0.73 9.9 10.7 1.8 1 1 0 1 1 1 0 BRE1 E3 ubiquitin ligase DUF948 PF06103.11 ORY07302.1 - 0.25 11.6 3.8 31 4.9 3.8 2.4 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) ACCA PF03255.14 ORY07302.1 - 3.9 7.3 7.0 5 7.0 2.3 2.1 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Glyco_hydro2_C5 PF18565.1 ORY07373.1 - 2.6e-33 113.9 0.3 4.9e-33 113.1 0.3 1.4 1 0 0 1 1 1 1 Glycoside hydrolase family 2 C-terminal domain 5 Glyco_hydro_2_C PF02836.17 ORY07373.1 - 3.2e-29 102.0 0.0 1e-28 100.3 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain DUF4982 PF16355.5 ORY07373.1 - 2.3e-25 88.3 0.3 1.4e-24 85.8 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4982) Glyco_hydro_2_N PF02837.18 ORY07373.1 - 1.1e-16 61.2 0.0 1.2e-15 57.8 0.0 2.4 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.21 ORY07373.1 - 1.4e-16 61.1 0.1 3.8e-16 59.7 0.1 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Invasin_D3 PF09134.10 ORY07373.1 - 1.3e-05 25.4 1.9 5.3e-05 23.5 1.9 2.1 1 1 0 1 1 1 1 Invasin, domain 3 Big_1 PF02369.16 ORY07373.1 - 0.0023 17.9 1.8 0.0083 16.1 1.8 2.0 1 0 0 1 1 1 1 Bacterial Ig-like domain (group 1) Nepo_coat PF03391.15 ORY07373.1 - 0.11 12.0 0.2 0.22 11.0 0.2 1.4 1 0 0 1 1 1 0 Nepovirus coat protein, central domain zf-CCCH_2 PF14608.6 ORY07375.1 - 0.027 14.9 0.9 0.063 13.8 0.9 1.6 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger NHL PF01436.21 ORY07376.1 - 0.1 12.7 2.6 15 5.8 0.1 3.5 4 0 0 4 4 4 0 NHL repeat DUF2789 PF10982.8 ORY07376.1 - 0.17 12.1 0.0 0.54 10.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2789) TPR_1 PF00515.28 ORY07377.1 - 2.2e-11 43.0 0.9 4.5e-05 23.1 0.0 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 ORY07377.1 - 1.2e-10 40.6 10.0 1.3e-05 24.9 0.0 5.8 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.6 ORY07377.1 - 6.9e-09 35.2 0.0 9.2e-05 22.4 0.0 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 ORY07377.1 - 1.4e-06 28.2 0.4 0.01 16.2 0.2 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 ORY07377.1 - 2.7e-06 26.9 0.3 0.032 13.9 0.0 3.9 2 1 1 3 3 3 2 TPR repeat TPR_9 PF13371.6 ORY07377.1 - 0.00055 20.0 2.8 0.0041 17.2 0.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 ORY07377.1 - 0.00091 19.8 4.0 0.0013 19.4 0.5 3.0 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 ORY07377.1 - 0.0014 18.5 3.1 1.4 9.1 0.1 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 ORY07377.1 - 0.0019 18.4 5.3 0.75 10.1 0.1 4.3 5 0 0 5 5 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY07377.1 - 0.038 14.2 0.5 0.21 11.8 0.5 2.4 2 0 0 2 2 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 ORY07377.1 - 0.12 13.2 8.9 0.8 10.7 0.0 5.6 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_3 PF07720.12 ORY07377.1 - 0.21 11.6 4.5 1.1 9.3 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 ORY07377.1 - 0.26 11.8 3.3 6.2 7.4 0.1 4.1 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 ORY07377.1 - 0.36 10.8 4.5 37 4.4 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 ORY07377.1 - 6.4 7.6 5.4 18 6.2 0.0 3.9 4 0 0 4 4 3 0 Tetratricopeptide repeat FSA_C PF10479.9 ORY07378.1 - 0.95 7.5 3.0 1.3 7.1 3.0 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Sugar_tr PF00083.24 ORY07379.1 - 7.3e-46 157.0 14.4 1.8e-45 155.6 14.4 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY07379.1 - 1e-11 44.4 11.2 1.5e-11 43.9 8.5 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily PsbJ PF01788.17 ORY07379.1 - 2.3 8.2 7.9 1.8 8.5 1.1 3.1 3 0 0 3 3 3 0 PsbJ Glyco_hydro_43 PF04616.14 ORY07380.1 - 7.4e-56 189.6 0.1 1.2e-55 188.9 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 ORY07380.1 - 5.1e-11 42.7 0.2 1.4e-10 41.2 0.0 1.8 2 0 0 2 2 2 1 Beta xylosidase C-terminal Concanavalin A-like domain Glyco_hydro_32C PF08244.12 ORY07380.1 - 0.078 13.0 0.1 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 32 C terminal Putative_PNPOx PF01243.20 ORY07380.1 - 0.2 11.9 0.0 0.61 10.3 0.0 1.8 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase adh_short PF00106.25 ORY07382.1 - 3.6e-14 52.7 0.1 5e-12 45.7 0.1 2.1 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 ORY07382.1 - 2e-06 27.6 0.2 1.5e-05 24.7 0.2 1.9 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase CPSF100_C PF13299.6 ORY07382.1 - 0.16 12.1 0.0 12 6.1 0.0 2.2 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal DUF829 PF05705.14 ORY07383.1 - 1.3e-08 35.0 1.0 4.9e-06 26.6 1.0 2.0 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) MFS_1 PF07690.16 ORY07384.1 - 7.6e-32 110.6 43.1 7.6e-32 110.6 43.1 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF4969 PF16339.5 ORY07384.1 - 0.033 14.5 0.2 0.14 12.5 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4969) CLASP_N PF12348.8 ORY07386.1 - 6e-122 405.5 2.6 3.7e-81 272.0 0.0 3.2 3 0 0 3 3 3 2 CLASP N terminal HEAT PF02985.22 ORY07386.1 - 7.1e-08 32.1 1.7 1.7 9.1 0.0 6.1 5 0 0 5 5 5 2 HEAT repeat Cnd1 PF12717.7 ORY07386.1 - 0.0011 19.0 0.3 0.54 10.3 0.0 4.0 4 1 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 MFS_1 PF07690.16 ORY07387.1 - 3.8e-31 108.3 34.8 3.8e-31 108.3 34.8 2.0 1 1 2 3 3 3 1 Major Facilitator Superfamily MFS_4 PF06779.14 ORY07387.1 - 4.6e-06 26.2 8.4 1.1e-05 24.9 8.4 1.6 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB Thi4 PF01946.17 ORY07388.1 - 4.3e-111 369.8 0.0 5.2e-111 369.5 0.0 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 ORY07388.1 - 1.8e-07 31.1 1.0 8.1e-07 28.9 0.7 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ORY07388.1 - 0.00033 20.8 0.4 0.00086 19.5 0.4 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 ORY07388.1 - 0.00043 19.5 0.9 0.00096 18.3 0.6 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 ORY07388.1 - 0.0046 16.2 0.0 0.0066 15.7 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ORY07388.1 - 0.021 14.8 0.1 0.021 14.8 0.1 1.9 3 0 0 3 3 3 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 ORY07388.1 - 0.071 12.2 2.1 0.23 10.5 1.1 2.2 2 1 1 3 3 3 0 FAD binding domain N-SET PF11764.8 ORY07388.1 - 0.21 11.7 0.0 0.32 11.1 0.0 1.2 1 0 0 1 1 1 0 COMPASS (Complex proteins associated with Set1p) component N Pyr_redox_3 PF13738.6 ORY07388.1 - 0.3 10.3 0.9 0.51 9.5 0.9 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase RhoGAP PF00620.27 ORY07389.1 - 6.6e-46 155.9 0.0 2.2e-45 154.2 0.0 2.0 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.22 ORY07389.1 - 9.9e-14 51.3 18.5 2e-09 37.5 1.7 2.4 2 0 0 2 2 2 2 LIM domain Desulfoferrod_N PF06397.12 ORY07389.1 - 0.43 10.2 12.3 9.9 5.9 1.9 3.6 2 1 1 3 3 3 0 Desulfoferrodoxin, N-terminal domain DUF4407 PF14362.6 ORY07389.1 - 0.6 9.4 6.1 1.1 8.6 6.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) APC_N_CC PF16689.5 ORY07389.1 - 0.61 10.2 3.3 5.5 7.1 1.0 2.8 2 0 0 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain CENP-H PF05837.12 ORY07389.1 - 0.76 10.2 12.3 0.18 12.3 0.2 3.1 2 0 0 2 2 2 0 Centromere protein H (CENP-H) DUF2757 PF10955.8 ORY07389.1 - 1.5 9.1 8.0 5.6 7.3 0.2 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2757) ABC_tran_CTD PF16326.5 ORY07389.1 - 2.4 8.5 13.3 0.13 12.6 3.2 3.1 2 1 0 3 3 3 0 ABC transporter C-terminal domain TBCA PF02970.16 ORY07389.1 - 4.1 7.8 9.4 3.3 8.1 7.0 2.1 1 1 1 2 2 2 0 Tubulin binding cofactor A DivIC PF04977.15 ORY07389.1 - 4.1 7.2 8.2 3.5 7.5 0.5 3.4 3 1 0 3 3 3 0 Septum formation initiator Zn-ribbon_8 PF09723.10 ORY07389.1 - 6.8 6.9 19.7 1.2 9.4 1.2 4.1 3 1 1 4 4 4 0 Zinc ribbon domain SCAB-PH PF17684.1 ORY07390.1 - 0.0054 17.0 0.3 0.0096 16.1 0.3 1.4 1 0 0 1 1 1 1 PH domain of plant-specific actin-binding protein zf-RING_2 PF13639.6 ORY07395.1 - 1.4e-11 44.5 11.1 2.1e-11 43.9 11.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 ORY07395.1 - 1.9e-08 33.9 10.1 3.4e-08 33.1 10.1 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 ORY07395.1 - 1.2e-06 28.3 10.5 2.4e-06 27.3 10.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 ORY07395.1 - 1.3e-05 25.0 5.4 1.8e-05 24.5 5.4 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORY07395.1 - 0.00011 22.1 7.6 0.00016 21.6 7.6 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 ORY07395.1 - 0.00024 20.9 9.8 0.00039 20.2 9.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORY07395.1 - 0.00025 21.0 5.8 0.00049 20.1 5.8 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 ORY07395.1 - 0.0057 16.9 16.0 0.018 15.3 16.0 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 ORY07395.1 - 0.041 13.7 6.6 0.079 12.8 6.6 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 ORY07395.1 - 0.062 13.4 4.4 0.12 12.5 4.4 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF711 PF05167.12 ORY07395.1 - 0.25 10.2 1.0 0.34 9.7 1.0 1.1 1 0 0 1 1 1 0 Uncharacterised ACR (DUF711) FANCL_C PF11793.8 ORY07395.1 - 1.9 8.7 8.8 7 6.9 8.8 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 ORY07395.1 - 2 8.1 9.8 3.3 7.4 9.8 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING-like PF08746.11 ORY07395.1 - 6.9 7.1 9.0 10 6.5 9.0 1.3 1 0 0 1 1 1 0 RING-like domain RINGv PF12906.7 ORY07395.1 - 8.4 6.6 11.4 16 5.7 11.4 1.4 1 0 0 1 1 1 0 RING-variant domain Fis1_TPR_C PF14853.6 ORY07396.1 - 3.3e-26 91.1 1.4 5.3e-26 90.4 1.4 1.3 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.6 ORY07396.1 - 1.1e-18 66.6 0.2 2.4e-18 65.5 0.2 1.6 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.17 ORY07396.1 - 0.00016 21.5 3.5 0.00034 20.5 3.5 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY07396.1 - 0.069 13.4 0.5 0.25 11.6 0.2 1.8 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 ORY07396.1 - 0.071 13.8 0.3 0.15 12.7 0.3 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.28 ORY07396.1 - 0.083 12.7 4.1 0.18 11.7 4.1 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat Spc24 PF08286.11 ORY07397.1 - 2.1e-34 117.9 0.0 6.8e-33 113.1 0.0 2.1 1 1 1 2 2 2 1 Spc24 subunit of Ndc80 FAST_1 PF06743.15 ORY07397.1 - 0.0035 17.2 0.6 1.8 8.6 0.1 2.2 1 1 1 2 2 2 2 FAST kinase-like protein, subdomain 1 Spike_torovirin PF17072.5 ORY07397.1 - 0.098 9.8 0.1 0.12 9.4 0.1 1.0 1 0 0 1 1 1 0 Torovirinae spike glycoprotein GYF PF02213.16 ORY07398.1 - 1.5e-16 59.7 1.1 3.8e-16 58.5 1.1 1.7 1 0 0 1 1 1 1 GYF domain GYF_2 PF14237.6 ORY07398.1 - 0.044 13.6 0.3 0.14 12.0 0.3 2.0 1 0 0 1 1 1 0 GYF domain 2 DUF5353 PF17304.2 ORY07401.1 - 3.3e-32 110.0 5.2 4.4e-32 109.6 5.2 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5353) MotA_ExbB PF01618.16 ORY07401.1 - 0.0086 15.8 0.1 0.056 13.2 0.0 2.0 2 0 0 2 2 2 1 MotA/TolQ/ExbB proton channel family TrbC PF04956.13 ORY07401.1 - 0.054 13.7 0.4 0.083 13.1 0.4 1.3 1 0 0 1 1 1 0 TrbC/VIRB2 family CHCH PF06747.13 ORY07402.1 - 1.6e-05 24.9 5.3 2.7e-05 24.2 5.3 1.4 1 0 0 1 1 1 1 CHCH domain SWIRM PF04433.17 ORY07403.1 - 1.3e-28 99.1 0.0 3.2e-28 97.9 0.0 1.7 1 0 0 1 1 1 1 SWIRM domain SWIRM-assoc_1 PF16495.5 ORY07403.1 - 8e-27 93.0 3.2 1.6e-26 92.1 3.2 1.5 1 0 0 1 1 1 1 SWIRM-associated region 1 Myb_DNA-binding PF00249.31 ORY07403.1 - 3.5e-09 36.7 0.1 8.4e-09 35.5 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORY07403.1 - 1.7e-06 28.2 1.5 2.1e-06 27.9 0.2 1.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 ORY07403.1 - 0.021 14.7 0.0 0.066 13.1 0.0 1.9 1 0 0 1 1 1 0 Myb DNA-binding like SANT_DAMP1_like PF16282.5 ORY07403.1 - 0.11 12.7 0.5 0.24 11.6 0.5 1.5 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 ARGLU PF15346.6 ORY07403.1 - 1.5 8.7 7.2 0.86 9.5 1.0 2.5 2 0 0 2 2 2 0 Arginine and glutamate-rich 1 ETF PF01012.21 ORY07404.1 - 2.2e-44 151.5 0.5 4.1e-44 150.6 0.5 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 ORY07404.1 - 4.8e-33 113.0 0.1 9.9e-33 112.0 0.1 1.6 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain Ion_trans_2 PF07885.16 ORY07405.1 - 1.8e-31 107.9 20.3 2.6e-17 62.5 4.7 3.0 3 0 0 3 3 3 2 Ion channel Lig_chan PF00060.26 ORY07405.1 - 2.6 7.9 7.4 0.21 11.4 1.3 2.3 2 1 0 2 2 2 0 Ligand-gated ion channel Myb_DNA-binding PF00249.31 ORY07407.1 - 7.3e-26 90.1 25.5 8.6e-11 41.9 0.7 5.4 6 0 0 6 6 6 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORY07407.1 - 3.5e-19 68.8 10.3 4.3e-09 36.5 0.2 4.8 3 1 2 5 5 5 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 ORY07407.1 - 0.00019 21.3 0.2 0.2 11.5 0.0 2.8 2 1 1 3 3 3 2 Myb DNA-binding like SANT_DAMP1_like PF16282.5 ORY07407.1 - 0.032 14.4 0.3 7.3 6.9 0.0 2.7 2 0 0 2 2 2 0 SANT/Myb-like domain of DAMP1 SLIDE PF09111.10 ORY07407.1 - 0.036 14.1 0.0 0.39 10.7 0.0 2.4 2 1 0 2 2 2 0 SLIDE rRNA_processing PF08524.11 ORY07408.1 - 2.9e-06 27.4 25.8 2.1e-05 24.6 25.8 1.9 1 1 0 1 1 1 1 rRNA processing Asp-B-Hydro_N PF05279.11 ORY07408.1 - 9.7 6.2 10.9 13 5.8 10.9 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF4210 PF13915.6 ORY07409.1 - 1.9e-33 114.9 0.1 3.9e-33 113.9 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.6 ORY07409.1 - 1.4e-23 82.8 0.6 2.7e-23 81.9 0.6 1.5 1 0 0 1 1 1 1 Chromosome segregation during meiosis F-box-like PF12937.7 ORY07410.1 - 0.00051 19.9 0.0 0.0015 18.4 0.0 1.8 1 0 0 1 1 1 1 F-box-like Phenol_monoox PF04663.12 ORY07410.1 - 1.2 9.3 3.3 12 6.1 0.1 2.4 2 0 0 2 2 2 0 Phenol hydroxylase conserved region Acetyltransf_10 PF13673.7 ORY07411.1 - 3.7e-06 26.9 0.0 6e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 ORY07411.1 - 9.7e-06 25.7 0.0 1.4e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 ORY07411.1 - 1.7e-05 24.5 0.0 2.5e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 GNAT acetyltransferase FR47 PF08445.10 ORY07411.1 - 2.3e-05 24.3 0.0 4e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 ORY07411.1 - 4.3e-05 23.8 0.0 8.6e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORY07411.1 - 5.5e-05 23.4 0.1 8.4e-05 22.8 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_CG PF14542.6 ORY07411.1 - 0.00036 20.6 0.0 0.00087 19.4 0.0 1.6 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase BSP PF04450.12 ORY07412.1 - 3.2e-75 252.5 0.0 4e-75 252.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase of plants and bacteria SprT-like PF10263.9 ORY07412.1 - 0.0055 16.6 0.1 0.01 15.7 0.1 1.5 1 0 0 1 1 1 1 SprT-like family Peptidase_M1 PF01433.20 ORY07412.1 - 0.063 12.8 0.1 0.12 11.9 0.1 1.4 1 0 0 1 1 1 0 Peptidase family M1 domain HAD_2 PF13419.6 ORY07413.1 - 1.7e-11 44.5 0.0 2.2e-11 44.2 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ORY07413.1 - 9.9e-08 32.5 0.0 2.3e-07 31.3 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ORY07413.1 - 2.9e-05 24.0 0.0 4.4e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like KH_1 PF00013.29 ORY07416.1 - 5e-33 112.7 0.9 7.5e-08 32.1 0.0 6.1 6 0 0 6 6 6 5 KH domain Rhodanese PF00581.20 ORY07417.1 - 3.5e-15 56.4 0.0 6.5e-15 55.6 0.0 1.4 2 0 0 2 2 2 1 Rhodanese-like domain Zn_clus PF00172.18 ORY07511.1 - 1.2e-08 34.9 8.5 1.2e-08 34.9 8.5 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sas10_Utp3 PF04000.15 ORY07512.1 - 5.9e-19 68.5 0.3 1.2e-18 67.5 0.3 1.5 1 0 0 1 1 1 1 Sas10/Utp3/C1D family DEAD PF00270.29 ORY07513.1 - 2e-51 174.2 0.0 2e-50 171.0 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY07513.1 - 1.6e-30 105.7 0.0 2.1e-28 98.8 0.0 3.2 4 0 0 4 4 4 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY07513.1 - 3.2e-10 40.3 0.0 2.1e-09 37.6 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 ORY07513.1 - 2.6e-06 26.8 0.0 2.6e-06 26.8 0.0 2.1 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase UTP25 PF06862.12 ORY07513.1 - 0.002 17.0 0.0 0.018 13.9 0.0 2.2 2 1 1 3 3 3 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 CMS1 PF14617.6 ORY07513.1 - 0.31 10.3 0.0 0.31 10.3 0.0 3.4 3 1 0 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit Red1 PF07964.11 ORY07513.1 - 6.6 4.8 16.9 9.3 4.3 16.9 1.1 1 0 0 1 1 1 0 Rec10 / Red1 Pkinase PF00069.25 ORY07515.1 - 2.9e-67 226.8 0.0 3.6e-67 226.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY07515.1 - 7.3e-32 110.7 0.0 9.3e-32 110.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 ORY07515.1 - 0.00024 20.5 0.3 0.00038 19.9 0.3 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 ORY07515.1 - 0.0028 16.7 0.2 0.0041 16.1 0.2 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 ORY07515.1 - 0.0065 15.8 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 ORY07515.1 - 0.018 15.0 0.1 0.038 13.9 0.1 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 ORY07515.1 - 0.033 13.2 0.1 0.05 12.7 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Evr1_Alr PF04777.13 ORY07516.1 - 5.5e-30 103.8 6.9 1.1e-29 102.8 5.1 1.9 2 0 0 2 2 2 1 Erv1 / Alr family PQ-loop PF04193.14 ORY07517.1 - 8.9e-23 79.8 3.6 5.9e-16 58.0 0.2 2.9 2 1 0 2 2 2 2 PQ loop repeat Peptidase_U4 PF03419.13 ORY07517.1 - 0.014 14.7 8.7 0.051 12.9 8.7 1.8 1 1 0 1 1 1 0 Sporulation factor SpoIIGA SLATT_1 PF18181.1 ORY07517.1 - 0.11 12.4 1.7 0.24 11.3 1.4 1.7 1 1 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 1 BCLP PF12304.8 ORY07517.1 - 0.13 11.8 3.2 0.31 10.6 3.1 1.6 1 1 0 1 1 1 0 Beta-casein like protein DUF1180 PF06679.12 ORY07519.1 - 0.097 13.1 1.6 0.12 12.8 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) MFS_1 PF07690.16 ORY07520.1 - 1.4e-34 119.5 22.2 2.3e-34 118.9 22.2 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 ORY07520.1 - 0.0031 16.4 2.4 0.0065 15.4 2.4 1.4 1 1 0 1 1 1 1 MFS_1 like family Gti1_Pac2 PF09729.9 ORY07521.1 - 2.7e-44 151.4 5.0 1.8e-37 129.2 0.1 2.7 2 1 1 3 3 3 2 Gti1/Pac2 family E1_DerP2_DerF2 PF02221.15 ORY07525.1 - 1.6e-09 38.3 0.1 2.1e-09 37.9 0.1 1.2 1 0 0 1 1 1 1 ML domain Lipase_GDSL_2 PF13472.6 ORY07526.1 - 9.4e-07 29.4 0.3 9.5e-06 26.1 0.0 2.4 1 1 1 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Peptidase_S8 PF00082.22 ORY07527.1 - 2.6e-20 72.9 0.0 4.5e-20 72.1 0.0 1.3 1 0 0 1 1 1 1 Subtilase family Mito_fiss_reg PF05308.11 ORY07527.1 - 2.1 8.3 6.8 3.3 7.7 5.7 1.8 2 0 0 2 2 2 0 Mitochondrial fission regulator Baculo_PEP_C PF04513.12 ORY07528.1 - 0.0053 16.8 1.6 0.0076 16.3 0.1 2.0 2 0 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus DHC_N1 PF08385.12 ORY07528.1 - 0.15 10.6 0.0 0.23 10.0 0.0 1.2 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 1 PGM_PMM_I PF02878.16 ORY07529.1 - 2.4e-41 140.7 0.1 7.1e-41 139.1 0.0 1.8 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 ORY07529.1 - 5.6e-21 75.1 0.2 1.6e-20 73.7 0.1 1.8 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 ORY07529.1 - 7.8e-14 51.9 0.0 1.5e-13 50.9 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 ORY07529.1 - 3.2e-07 30.4 0.0 9e-07 29.0 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Homeodomain PF00046.29 ORY07529.1 - 0.0084 15.9 0.0 0.024 14.5 0.0 1.7 1 0 0 1 1 1 1 Homeodomain FA_desaturase PF00487.24 ORY07530.1 - 3.3e-25 89.4 26.5 5.4e-25 88.7 26.5 1.4 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 ORY07530.1 - 1.5e-09 37.8 0.0 3.3e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Hydrolase_4 PF12146.8 ORY07531.1 - 9e-26 90.6 0.1 1.1e-24 87.0 0.1 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ORY07531.1 - 5.1e-23 82.0 0.0 5.5e-20 72.1 0.1 2.0 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORY07531.1 - 2.6e-17 64.2 0.0 4e-17 63.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 ORY07531.1 - 6.3e-07 29.3 0.0 2.9e-05 23.9 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Ndr PF03096.14 ORY07531.1 - 4.5e-06 25.6 0.0 7e-06 24.9 0.0 1.4 1 0 0 1 1 1 1 Ndr family Abhydrolase_2 PF02230.16 ORY07531.1 - 7.7e-06 25.9 0.1 0.81 9.5 0.0 3.1 2 1 1 3 3 3 2 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 ORY07531.1 - 2.3e-05 23.9 0.0 0.051 13.0 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family DLH PF01738.18 ORY07531.1 - 0.00011 21.9 0.0 0.053 13.1 0.0 2.1 2 0 0 2 2 2 2 Dienelactone hydrolase family Ser_hydrolase PF06821.13 ORY07531.1 - 0.00013 21.9 0.1 0.0027 17.6 0.1 2.2 1 1 0 2 2 2 1 Serine hydrolase Thioesterase PF00975.20 ORY07531.1 - 0.00047 20.3 0.1 0.00078 19.6 0.1 1.3 1 0 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.13 ORY07531.1 - 0.0005 19.9 0.2 0.00082 19.2 0.2 1.3 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.14 ORY07531.1 - 0.001 18.6 0.0 0.0017 17.9 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Esterase PF00756.20 ORY07531.1 - 0.002 17.8 0.0 0.0029 17.3 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Abhydrolase_3 PF07859.13 ORY07531.1 - 0.0025 17.7 0.0 0.0039 17.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold UPF0227 PF05728.12 ORY07531.1 - 0.0042 17.1 0.0 0.0076 16.2 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) Chlorophyllase2 PF12740.7 ORY07531.1 - 0.0073 15.2 0.2 0.014 14.3 0.2 1.6 1 1 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_4 PF08386.10 ORY07531.1 - 0.0079 16.3 0.0 0.013 15.6 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein LIDHydrolase PF10230.9 ORY07531.1 - 0.0087 15.6 0.0 0.029 14.0 0.0 1.7 2 0 0 2 2 2 1 Lipid-droplet associated hydrolase PAF-AH_p_II PF03403.13 ORY07531.1 - 0.016 13.8 0.0 1.4 7.4 0.0 2.2 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II BAAT_C PF08840.11 ORY07531.1 - 0.022 14.7 0.0 1.5 8.7 0.0 2.1 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal FSH1 PF03959.13 ORY07531.1 - 0.058 13.0 0.0 1.9 8.1 0.0 2.7 1 1 1 2 2 2 0 Serine hydrolase (FSH1) DUF1057 PF06342.12 ORY07531.1 - 0.067 12.2 0.0 0.091 11.8 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) DUF915 PF06028.11 ORY07531.1 - 0.07 12.5 0.0 0.15 11.4 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Lipase_3 PF01764.25 ORY07531.1 - 0.08 12.8 0.1 0.12 12.2 0.1 1.3 1 0 0 1 1 1 0 Lipase (class 3) DUF1100 PF06500.11 ORY07531.1 - 0.15 10.8 0.0 0.2 10.4 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) Cyt-b5 PF00173.28 ORY07533.1 - 2.5e-18 66.0 0.2 2.8e-18 65.8 0.2 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Exonuc_VII_L PF02601.15 ORY07534.1 - 0.0054 16.3 10.2 0.0054 16.3 10.2 2.1 1 1 0 2 2 2 1 Exonuclease VII, large subunit DUF3450 PF11932.8 ORY07534.1 - 0.088 12.1 23.4 0.37 10.0 21.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) SLATT_6 PF18169.1 ORY07534.1 - 0.45 10.1 3.4 0.95 9.0 3.4 1.5 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 6 Borrelia_P83 PF05262.11 ORY07534.1 - 4.8 5.6 23.4 7.1 5.0 23.4 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Allantoicase PF03561.15 ORY07535.1 - 4.3e-94 312.1 0.1 1.6e-49 167.6 0.0 2.1 2 0 0 2 2 2 2 Allantoicase repeat DIL PF01843.19 ORY07536.1 - 9.8e-31 106.1 1.6 1.9e-30 105.2 1.6 1.5 1 0 0 1 1 1 1 DIL domain Ank_2 PF12796.7 ORY07536.1 - 7.8e-14 52.0 0.1 2.9e-13 50.2 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY07536.1 - 2.8e-11 43.7 0.1 3.4e-06 27.5 0.0 4.5 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 ORY07536.1 - 8.8e-10 38.6 0.0 0.004 17.5 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 ORY07536.1 - 3e-08 33.8 0.0 6.6e-07 29.5 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY07536.1 - 1.2e-07 31.4 0.1 0.011 16.2 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeat HATPase_c PF02518.26 ORY07537.1 - 3.8e-31 107.9 0.0 8.3e-31 106.8 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 ORY07537.1 - 2.7e-20 72.2 0.3 6.1e-19 67.8 0.0 3.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain Response_reg PF00072.24 ORY07537.1 - 3.1e-17 62.8 0.0 7.7e-17 61.5 0.0 1.8 1 0 0 1 1 1 1 Response regulator receiver domain AAA_16 PF13191.6 ORY07537.1 - 7.3e-11 42.7 2.8 8.3e-11 42.6 0.0 2.7 3 0 0 3 3 3 1 AAA ATPase domain Pkinase PF00069.25 ORY07537.1 - 1.2e-10 41.2 0.0 2.7e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain GAF_2 PF13185.6 ORY07537.1 - 3.3e-10 40.4 0.0 8.1e-10 39.1 0.0 1.8 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 ORY07537.1 - 3.2e-07 31.0 0.0 1e-06 29.4 0.0 2.0 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 ORY07537.1 - 9.2e-05 22.8 0.1 0.00038 20.8 0.0 2.2 2 0 0 2 2 2 1 GAF domain NACHT PF05729.12 ORY07537.1 - 0.00016 21.6 0.2 0.75 9.7 0.0 2.6 2 0 0 2 2 2 2 NACHT domain Patatin PF01734.22 ORY07539.1 - 3.8e-20 72.9 0.0 1.7e-11 44.7 0.0 2.3 2 0 0 2 2 2 2 Patatin-like phospholipase Dimer_Tnp_hAT PF05699.14 ORY07540.1 - 0.0025 17.6 0.1 0.029 14.2 0.1 2.1 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region Pheromone PF08015.11 ORY07540.1 - 0.94 10.6 4.4 0.33 12.0 1.6 1.7 2 0 0 2 2 2 0 Fungal mating-type pheromone CinA PF02464.17 ORY07541.1 - 1.2e-35 122.4 1.2 1.3e-35 122.3 1.2 1.0 1 0 0 1 1 1 1 Competence-damaged protein F-box-like PF12937.7 ORY07542.1 - 1.2e-05 25.1 2.0 3.7e-05 23.5 2.0 1.8 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 ORY07542.1 - 0.069 13.0 0.9 0.16 11.9 0.3 1.9 2 0 0 2 2 2 0 F-box domain p450 PF00067.22 ORY07544.1 - 4.1e-44 151.1 0.0 5.5e-44 150.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MOSC PF03473.17 ORY07546.1 - 1.5e-34 118.9 0.0 2.1e-34 118.3 0.0 1.2 1 0 0 1 1 1 1 MOSC domain Patatin PF01734.22 ORY07548.1 - 1.7e-13 51.2 0.0 6.2e-13 49.4 0.0 1.9 1 1 0 1 1 1 1 Patatin-like phospholipase HET PF06985.11 ORY07549.1 - 5e-25 88.6 0.0 5.4e-25 88.5 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Abhydrolase_3 PF07859.13 ORY07550.1 - 8.8e-38 130.3 0.0 1.4e-37 129.6 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 ORY07550.1 - 1.6e-05 24.7 0.4 7.8e-05 22.4 0.4 1.9 1 1 0 1 1 1 1 Putative esterase Abhydrolase_6 PF12697.7 ORY07550.1 - 6.1e-05 23.7 0.1 0.00012 22.8 0.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.8 ORY07550.1 - 0.021 14.4 0.0 0.032 13.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DLH PF01738.18 ORY07550.1 - 0.063 12.8 0.0 0.19 11.2 0.0 1.8 2 0 0 2 2 2 0 Dienelactone hydrolase family Chlorophyllase2 PF12740.7 ORY07550.1 - 0.096 11.6 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Peptidase_S9 PF00326.21 ORY07550.1 - 0.096 12.1 0.0 0.34 10.4 0.0 1.7 2 0 0 2 2 2 0 Prolyl oligopeptidase family Lectin_leg-like PF03388.13 ORY07551.1 - 3.4e-29 101.8 0.0 1.4e-28 99.9 0.0 1.8 2 0 0 2 2 2 1 Legume-like lectin family Baculo_p24 PF05073.12 ORY07551.1 - 0.0051 16.6 1.6 0.0051 16.6 1.6 1.6 1 1 0 1 1 1 1 Baculovirus P24 capsid protein Baculo_PEP_C PF04513.12 ORY07551.1 - 0.016 15.2 0.7 0.47 10.5 0.1 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Nup54 PF13874.6 ORY07551.1 - 0.024 14.8 1.2 0.024 14.8 1.2 2.0 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 DUF3492 PF11997.8 ORY07551.1 - 0.037 13.8 0.4 0.037 13.8 0.4 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF3492) DUF3483 PF11982.8 ORY07551.1 - 0.051 13.2 0.0 0.093 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3483) DUF1515 PF07439.11 ORY07551.1 - 0.068 13.2 1.4 0.14 12.2 1.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) LMBR1 PF04791.16 ORY07551.1 - 0.086 11.7 1.0 0.13 11.1 1.0 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein MitMem_reg PF13012.6 ORY07551.1 - 0.091 13.2 1.4 0.18 12.3 1.4 1.6 1 0 0 1 1 1 0 Maintenance of mitochondrial structure and function DUF1664 PF07889.12 ORY07551.1 - 0.36 10.9 3.6 1 9.4 3.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Mrx7 PF10906.8 ORY07551.1 - 2.9 8.2 8.4 6.9 7.0 0.0 3.3 3 0 0 3 3 3 0 MIOREX complex component 7 Velvet PF11754.8 ORY07551.1 - 3.7 7.4 8.8 3.3 7.6 7.4 1.5 1 1 0 1 1 1 0 Velvet factor Phage_GPO PF05929.11 ORY07551.1 - 6 6.4 8.9 0.16 11.5 0.4 1.9 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Band_7 PF01145.25 ORY07552.1 - 1.9e-21 76.9 5.2 1.9e-21 76.9 5.2 1.6 2 1 0 2 2 2 1 SPFH domain / Band 7 family DNA_primase_S PF01896.19 ORY07553.1 - 8.6e-65 218.1 0.0 1.1e-64 217.7 0.0 1.2 1 0 0 1 1 1 1 DNA primase small subunit Ank_3 PF13606.6 ORY07554.1 - 1.3e-05 25.2 0.0 0.4 11.4 0.0 3.0 2 1 1 3 3 3 2 Ankyrin repeat Ank PF00023.30 ORY07554.1 - 2e-05 24.8 0.1 0.45 11.0 0.1 3.1 1 1 0 1 1 1 1 Ankyrin repeat Ank_2 PF12796.7 ORY07554.1 - 6.2e-05 23.5 0.0 0.0057 17.2 0.0 2.1 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY07554.1 - 0.00023 21.7 0.0 0.053 14.1 0.0 2.4 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 ORY07554.1 - 0.0014 18.9 0.0 3.3 8.1 0.0 2.9 1 1 2 3 3 3 2 Ankyrin repeats (many copies) DUF1917 PF08939.10 ORY07555.1 - 4.4e-76 256.2 0.0 6e-76 255.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1917) Amidohydro_1 PF01979.20 ORY07556.1 - 3.6e-29 102.2 0.0 8.7e-29 100.9 0.0 1.6 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 ORY07556.1 - 6.9e-17 62.1 0.0 3.8e-11 43.1 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family 5-nucleotidase PF06189.12 ORY07556.1 - 0.14 11.0 0.0 0.24 10.3 0.0 1.2 1 0 0 1 1 1 0 5'-nucleotidase GPR15L PF15854.5 ORY07556.1 - 0.21 11.8 0.3 0.82 9.9 0.0 1.9 2 0 0 2 2 2 0 G-protein coupled receptor ligand 15 ubiquitin PF00240.23 ORY07557.1 - 4.7e-34 116.0 0.6 7.9e-34 115.2 0.6 1.4 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.19 ORY07557.1 - 1.3e-26 92.5 2.1 1.3e-26 92.5 2.1 2.0 2 0 0 2 2 2 1 Ribosomal protein S27a Rad60-SLD PF11976.8 ORY07557.1 - 2.7e-16 59.2 0.7 4.9e-16 58.3 0.7 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 ORY07557.1 - 2.7e-05 24.5 0.3 0.00013 22.4 0.1 2.1 2 1 0 2 2 2 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 ORY07557.1 - 0.00071 19.7 0.7 0.0016 18.5 0.7 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 ORY07557.1 - 0.0049 17.2 1.0 0.0076 16.6 0.1 1.7 1 1 1 2 2 2 1 Ubiquitin-like domain TBK1_ULD PF18396.1 ORY07557.1 - 0.0054 16.6 0.0 0.0082 16.1 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain DUF2407 PF10302.9 ORY07557.1 - 0.013 16.1 0.9 0.018 15.6 0.9 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 ORY07557.1 - 0.021 14.9 1.0 5.9 7.0 0.2 2.4 2 0 0 2 2 2 0 Ubiquitin-like domain IBR PF01485.21 ORY07557.1 - 0.059 13.6 0.3 0.1 12.9 0.3 1.5 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain zf-C2H2 PF00096.26 ORY07558.1 - 3.1e-11 43.1 14.5 0.00014 22.1 5.1 4.2 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY07558.1 - 1.7e-08 34.5 9.1 0.00012 22.4 0.2 3.7 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORY07558.1 - 2.4e-06 27.9 12.6 0.084 13.8 4.0 4.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_11 PF16622.5 ORY07558.1 - 0.0052 16.5 7.3 0.4 10.5 3.8 2.6 2 0 0 2 2 2 2 zinc-finger C2H2-type zf-LYAR PF08790.11 ORY07558.1 - 0.63 10.0 3.6 1.3 9.0 0.0 2.8 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-C2H2_6 PF13912.6 ORY07558.1 - 1.9 8.6 10.1 5.2 7.2 0.1 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger p450 PF00067.22 ORY07559.1 - 6.1e-53 180.2 0.0 1.5e-52 178.9 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 AAA PF00004.29 ORY07562.1 - 2.3e-19 70.1 0.0 3.6e-19 69.5 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) CDC48_2 PF02933.17 ORY07562.1 - 2.9e-10 39.8 0.1 3.1e-08 33.3 0.0 2.4 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_22 PF13401.6 ORY07562.1 - 5e-05 23.6 0.0 9.1e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ORY07562.1 - 0.00015 22.2 0.0 0.00047 20.6 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 ORY07562.1 - 0.00049 20.1 0.0 0.0009 19.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) CDC48_N PF02359.18 ORY07562.1 - 0.00056 20.0 0.0 0.001 19.2 0.0 1.4 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain Mg_chelatase PF01078.21 ORY07562.1 - 0.0015 18.0 0.0 0.0024 17.3 0.0 1.2 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI ATPase PF06745.13 ORY07562.1 - 0.0028 17.1 0.1 0.0041 16.5 0.1 1.2 1 0 0 1 1 1 1 KaiC AAA_18 PF13238.6 ORY07562.1 - 0.0029 18.2 0.0 0.0069 16.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 ORY07562.1 - 0.0031 17.6 0.0 0.005 17.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 ORY07562.1 - 0.0037 16.5 0.0 0.0057 15.9 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain RuvB_N PF05496.12 ORY07562.1 - 0.0074 16.0 0.1 0.023 14.4 0.1 1.7 1 1 1 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 ORY07562.1 - 0.0079 15.9 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 ORY07562.1 - 0.011 16.1 0.0 0.019 15.3 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_7 PF12775.7 ORY07562.1 - 0.011 15.3 0.0 0.019 14.5 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 ORY07562.1 - 0.034 14.3 0.0 0.057 13.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 ORY07562.1 - 0.035 13.8 0.0 0.057 13.1 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein ABC_tran PF00005.27 ORY07562.1 - 0.044 14.3 0.0 0.093 13.2 0.0 1.4 1 0 0 1 1 1 0 ABC transporter TsaE PF02367.17 ORY07562.1 - 0.05 13.6 0.0 0.087 12.8 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 ORY07562.1 - 0.077 13.2 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 ORY07562.1 - 0.097 12.7 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 ORY07562.1 - 0.1 12.3 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 ORY07562.1 - 0.13 11.4 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_3 PF07726.11 ORY07562.1 - 0.14 12.0 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 ORY07562.1 - 0.16 11.7 0.0 0.26 11.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 ORY07562.1 - 0.17 12.2 0.0 0.34 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 ORY07562.1 - 0.2 11.6 0.5 7.8 6.3 0.0 2.1 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 ORY07562.1 - 0.2 11.3 0.0 0.32 10.7 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain AMP-binding PF00501.28 ORY07645.1 - 5.3e-70 236.1 0.0 7.2e-70 235.7 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 ORY07645.1 - 1.2e-62 212.1 0.0 4e-34 118.1 0.0 3.0 4 0 0 4 4 4 2 Condensation domain PP-binding PF00550.25 ORY07645.1 - 6e-23 81.0 1.5 2.9e-10 40.3 0.0 3.2 3 0 0 3 3 3 2 Phosphopantetheine attachment site TPR_12 PF13424.6 ORY07649.1 - 2.1e-08 34.3 4.3 0.0021 18.3 0.1 4.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 ORY07649.1 - 0.0039 17.0 2.8 0.2 11.6 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 ORY07649.1 - 0.0053 16.8 13.2 0.023 14.8 0.3 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_MalT PF17874.1 ORY07649.1 - 0.0062 15.9 0.1 0.13 11.6 0.0 2.7 3 0 0 3 3 3 1 MalT-like TPR region TPR_17 PF13431.6 ORY07649.1 - 0.12 12.8 0.0 2.8 8.5 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 ORY07649.1 - 0.25 12.3 10.4 7.5 7.7 0.1 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat SRAP PF02586.14 ORY07650.1 - 6.7e-85 284.1 0.0 9e-85 283.7 0.0 1.2 1 0 0 1 1 1 1 SOS response associated peptidase (SRAP) Isochorismatase PF00857.20 ORY07651.1 - 3.1e-26 92.6 0.0 1.2e-19 71.1 0.0 2.4 2 0 0 2 2 2 2 Isochorismatase family 2OG-FeII_Oxy_2 PF13532.6 ORY07651.1 - 6.9e-25 88.4 0.1 1.6e-24 87.2 0.1 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily GST_C_2 PF13410.6 ORY07651.1 - 6.5e-05 22.9 0.0 0.00014 21.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 ORY07651.1 - 0.00033 20.8 0.0 0.0008 19.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 ORY07651.1 - 0.11 12.7 0.0 0.28 11.4 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain NDUFA12 PF05071.16 ORY07652.1 - 3.4e-10 40.6 1.0 3.4e-10 40.6 1.0 1.9 2 0 0 2 2 2 1 NADH ubiquinone oxidoreductase subunit NDUFA12 CH PF00307.31 ORY07653.1 - 1e-13 51.4 0.0 1.7e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain zf-U1 PF06220.12 ORY07654.1 - 1.7e-16 59.7 1.4 2.8e-16 59.0 1.4 1.3 1 0 0 1 1 1 1 U1 zinc finger NmrA PF05368.13 ORY07655.1 - 1.2e-13 51.2 0.0 1.4e-13 50.9 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ORY07655.1 - 2.7e-08 33.9 0.0 3.2e-07 30.4 0.0 2.3 1 1 1 2 2 2 1 NAD(P)H-binding Shikimate_DH PF01488.20 ORY07655.1 - 6.1e-07 29.6 0.0 1.2e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 ORY07655.1 - 0.00044 20.5 0.0 0.003 17.8 0.0 2.1 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain WD40 PF00400.32 ORY07656.1 - 1.5e-44 149.1 25.5 1.4e-08 35.2 0.2 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY07656.1 - 4.3e-09 36.5 0.3 0.068 13.5 0.0 4.4 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ORY07656.1 - 0.00059 18.6 6.2 0.18 10.4 0.1 4.2 2 1 3 5 5 5 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 ORY07656.1 - 0.003 16.6 0.0 9.2 5.1 0.0 3.9 2 2 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 ORY07656.1 - 0.0051 16.7 0.0 1.4 8.7 0.0 2.9 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 ORY07656.1 - 0.0098 15.3 0.0 0.75 9.1 0.0 2.6 2 1 0 3 3 3 1 WD40-like domain PD40 PF07676.12 ORY07656.1 - 0.013 15.4 0.5 22 5.1 0.0 4.5 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat ECH_1 PF00378.20 ORY07657.1 - 1.2e-43 149.3 0.0 2e-43 148.5 0.0 1.3 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ORY07657.1 - 2.3e-29 102.9 0.0 4.6e-28 98.7 0.0 1.9 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Lipase_GDSL_2 PF13472.6 ORY07658.1 - 1.5e-09 38.5 0.7 5.9e-07 30.0 0.0 2.9 3 0 0 3 3 3 2 GDSL-like Lipase/Acylhydrolase family Glyco_hydro_28 PF00295.17 ORY07659.1 - 5.6e-49 167.0 14.5 7.3e-49 166.6 14.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 ICAM_N PF03921.14 ORY07659.1 - 0.073 12.8 1.4 0.13 12.0 0.1 2.0 2 0 0 2 2 2 0 Intercellular adhesion molecule (ICAM), N-terminal domain Esterase_phd PF10503.9 ORY07660.1 - 1.8e-23 83.2 1.0 2.4e-23 82.8 1.0 1.2 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 ORY07660.1 - 7.2e-12 45.2 1.5 1e-11 44.7 1.5 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.28 ORY07660.1 - 2.3e-06 26.8 1.4 2.9e-06 26.4 1.4 1.1 1 0 0 1 1 1 1 Carboxylesterase family Esterase PF00756.20 ORY07660.1 - 0.00039 20.2 0.5 0.00051 19.8 0.5 1.2 1 0 0 1 1 1 1 Putative esterase Abhydrolase_3 PF07859.13 ORY07660.1 - 0.0016 18.3 0.1 0.0024 17.8 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 ORY07660.1 - 0.062 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase UPF0227 PF05728.12 ORY07660.1 - 0.091 12.7 0.0 1.6 8.7 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) Abhydrolase_1 PF00561.20 ORY07660.1 - 0.095 12.3 0.9 0.48 10.0 0.4 1.9 1 1 1 2 2 2 0 alpha/beta hydrolase fold SH3_1 PF00018.28 ORY07663.1 - 5.7e-15 54.6 0.1 8.9e-15 54.0 0.1 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 ORY07663.1 - 1.4e-10 40.9 0.1 3.4e-10 39.6 0.0 1.7 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 ORY07663.1 - 1.2e-07 31.3 0.0 2e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain adh_short PF00106.25 ORY07664.1 - 1.1e-35 122.9 0.0 1.6e-35 122.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY07664.1 - 5.2e-18 65.5 0.0 8.8e-18 64.7 0.0 1.3 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY07664.1 - 8.9e-07 29.0 0.0 2.1e-06 27.8 0.0 1.5 1 1 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 ORY07664.1 - 0.0015 18.8 0.1 0.0031 17.8 0.1 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 ORY07664.1 - 0.0015 18.6 0.0 0.0027 17.8 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DUF1776 PF08643.10 ORY07664.1 - 0.0054 16.1 0.1 0.011 15.1 0.0 1.5 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) Eno-Rase_NADH_b PF12242.8 ORY07664.1 - 0.0065 16.2 0.1 0.015 15.0 0.1 1.7 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.21 ORY07664.1 - 0.036 13.5 0.0 0.064 12.7 0.0 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 ORY07664.1 - 0.057 13.3 0.0 0.082 12.8 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding COesterase PF00135.28 ORY07665.1 - 9e-59 199.7 0.0 1.2e-58 199.3 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 ORY07665.1 - 1.4e-06 28.4 0.1 0.0003 20.7 0.0 3.1 2 1 0 2 2 2 1 alpha/beta hydrolase fold MACPF PF01823.19 ORY07667.1 - 1.9e-14 54.2 0.0 3.2e-14 53.5 0.0 1.2 1 0 0 1 1 1 1 MAC/Perforin domain BatA PF07584.11 ORY07671.1 - 0.0011 19.2 0.2 0.0017 18.7 0.2 1.2 1 0 0 1 1 1 1 Aerotolerance regulator N-terminal Cation_efflux PF01545.21 ORY07671.1 - 0.025 14.3 0.0 0.03 14.1 0.0 1.1 1 0 0 1 1 1 0 Cation efflux family RCR PF12273.8 ORY07671.1 - 0.039 14.6 1.0 0.06 14.0 1.0 1.4 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red CcmD PF04995.14 ORY07671.1 - 0.064 13.4 0.7 0.12 12.5 0.7 1.5 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) LtrA PF06772.11 ORY07671.1 - 0.12 11.6 0.2 0.15 11.3 0.2 1.1 1 0 0 1 1 1 0 Bacterial low temperature requirement A protein (LtrA) Gram_pos_anchor PF00746.21 ORY07671.1 - 0.15 12.0 0.0 0.29 11.1 0.0 1.4 1 0 0 1 1 1 0 LPXTG cell wall anchor motif Glucos_trans_II PF14264.6 ORY07671.1 - 0.17 11.3 0.1 0.2 11.0 0.1 1.1 1 0 0 1 1 1 0 Glucosyl transferase GtrII Tfb5 PF06331.12 ORY07672.1 - 6.8e-25 86.8 3.3 7.4e-25 86.7 3.3 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 Med4 PF10018.9 ORY07672.1 - 0.013 15.2 2.6 0.014 15.1 2.6 1.0 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 RRF_GI PF12614.8 ORY07672.1 - 0.11 12.7 0.8 0.13 12.5 0.8 1.1 1 0 0 1 1 1 0 Ribosome recycling factor GFA PF04828.14 ORY07673.1 - 3.3e-23 81.9 0.1 4.5e-23 81.4 0.1 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Zn_ribbon_recom PF13408.6 ORY07673.1 - 0.17 12.4 0.0 0.17 12.4 0.0 2.9 2 1 1 3 3 3 0 Recombinase zinc beta ribbon domain Med1 PF10744.9 ORY07675.1 - 8.7e-86 288.5 0.0 1.3e-85 288.0 0.0 1.2 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription subunit 1 DUF2975 PF11188.8 ORY07676.1 - 0.12 12.2 0.4 0.25 11.2 0.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2975) Gln-synt_C PF00120.24 ORY07677.1 - 4.7e-19 68.6 0.0 1.1e-17 64.1 0.0 2.1 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 ORY07677.1 - 5.5e-13 48.5 0.0 1.3e-12 47.2 0.0 1.6 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain SSP160 PF06933.11 ORY07680.1 - 0.0047 15.2 11.3 0.0047 15.2 11.3 1.9 2 0 0 2 2 2 1 Special lobe-specific silk protein SSP160 VSP PF03302.13 ORY07680.1 - 0.0072 15.2 2.5 0.011 14.6 2.5 1.2 1 0 0 1 1 1 1 Giardia variant-specific surface protein DUF4512 PF14975.6 ORY07680.1 - 0.11 13.3 0.9 2 9.2 1.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4512) TMEM154 PF15102.6 ORY07680.1 - 0.19 11.6 0.1 0.19 11.6 0.1 1.7 2 0 0 2 2 2 0 TMEM154 protein family MGC-24 PF05283.11 ORY07680.1 - 4.4 7.8 13.7 0.03 14.8 3.9 2.3 3 0 0 3 3 3 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Phage_FRD3 PF05798.11 ORY07682.1 - 0.0085 16.3 0.1 0.019 15.3 0.1 1.5 1 0 0 1 1 1 1 Bacteriophage FRD3 protein FAD-oxidase_C PF02913.19 ORY07683.1 - 4.2e-48 164.2 0.0 5.5e-48 163.8 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 ORY07683.1 - 2.7e-32 111.4 0.0 5e-32 110.5 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain MdcG PF10620.9 ORY07683.1 - 0.16 11.7 0.0 0.38 10.5 0.0 1.6 1 0 0 1 1 1 0 Phosphoribosyl-dephospho-CoA transferase MdcG SET PF00856.28 ORY07684.1 - 1.4e-11 45.1 0.1 5.5e-11 43.2 0.1 2.0 2 1 0 2 2 2 1 SET domain Pkinase PF00069.25 ORY07686.1 - 6.2e-07 29.1 0.0 1.2e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY07686.1 - 0.00031 20.1 0.0 0.093 12.0 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Ank_2 PF12796.7 ORY07687.1 - 1.4e-25 89.6 1.1 1.9e-06 28.4 0.0 6.7 5 2 0 7 7 7 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY07687.1 - 2e-25 88.8 4.0 0.0016 19.0 0.0 8.5 6 1 2 8 8 8 6 Ankyrin repeats (many copies) Pkinase PF00069.25 ORY07687.1 - 6.8e-22 78.1 0.0 1.1e-21 77.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Ank PF00023.30 ORY07687.1 - 6.8e-20 70.6 10.9 0.02 15.3 0.0 9.1 9 0 0 9 9 9 6 Ankyrin repeat Ank_5 PF13857.6 ORY07687.1 - 3.8e-19 68.5 4.1 0.00011 22.4 0.0 7.0 6 0 0 6 6 6 4 Ankyrin repeats (many copies) Pkinase_Tyr PF07714.17 ORY07687.1 - 1.4e-18 67.1 0.0 2.3e-18 66.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_3 PF13606.6 ORY07687.1 - 2.2e-18 64.4 3.6 0.02 15.4 0.0 7.5 8 0 0 8 8 8 5 Ankyrin repeat Acyl-CoA_dh_1 PF00441.24 ORY07760.1 - 1.6e-32 112.8 1.6 2.6e-32 112.1 1.6 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 ORY07760.1 - 2.5e-21 75.7 0.1 4.3e-21 74.9 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 ORY07760.1 - 3.6e-15 56.6 0.2 1.6e-14 54.5 0.0 2.3 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 ORY07760.1 - 4.1e-07 30.3 0.1 6.3e-07 29.7 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Fungal_trans PF04082.18 ORY07763.1 - 3.4e-33 114.8 0.1 7.4e-33 113.7 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY07763.1 - 0.00025 21.1 15.5 0.00044 20.3 15.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Choline_kinase PF01633.20 ORY07764.1 - 1.6e-49 168.4 0.0 4.3e-47 160.5 0.0 2.3 2 0 0 2 2 2 2 Choline/ethanolamine kinase APH PF01636.23 ORY07764.1 - 7.7e-10 39.1 0.2 2.1e-08 34.4 0.2 2.8 2 1 0 2 2 2 1 Phosphotransferase enzyme family SAT PF16073.5 ORY07765.1 - 9.7e-79 264.5 4.6 9.9e-79 264.5 0.5 2.6 2 1 1 3 3 3 1 Starter unit:ACP transacylase in aflatoxin biosynthesis ketoacyl-synt PF00109.26 ORY07765.1 - 1.7e-77 260.4 0.0 3.2e-77 259.5 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 ORY07765.1 - 8.8e-38 130.6 0.0 1.6e-37 129.7 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 ORY07765.1 - 8.7e-35 119.3 2.7 2.3e-34 117.9 2.7 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.20 ORY07765.1 - 4.8e-25 89.0 0.0 1.5e-24 87.4 0.0 1.9 2 0 0 2 2 2 1 Thioesterase domain PP-binding PF00550.25 ORY07765.1 - 9.3e-23 80.4 5.0 8.3e-12 45.3 0.4 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site PS-DH PF14765.6 ORY07765.1 - 2.7e-16 59.7 0.0 4.3e-16 59.0 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 ORY07765.1 - 1.3e-07 32.1 0.2 7.2e-07 29.7 0.0 2.4 3 0 0 3 3 3 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 ORY07765.1 - 3.1e-06 26.8 0.0 7.7e-06 25.4 0.0 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain Abhydrolase_6 PF12697.7 ORY07765.1 - 9.5e-06 26.4 0.4 0.0024 18.5 0.1 2.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family PEP_mutase PF13714.6 ORY07765.1 - 0.0092 15.5 0.0 0.37 10.2 0.0 2.4 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase Hydrolase_4 PF12146.8 ORY07765.1 - 0.039 13.2 0.0 0.21 10.8 0.0 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 EthD PF07110.11 ORY07766.1 - 2.8e-22 79.6 0.5 3.4e-22 79.4 0.5 1.1 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 ORY07766.1 - 0.065 13.7 0.1 0.15 12.5 0.1 1.6 1 1 0 1 1 1 0 Methylmuconolactone methyl-isomerase FAD_binding_3 PF01494.19 ORY07767.1 - 1.6e-17 63.8 0.0 9.2e-08 31.7 0.0 3.1 3 0 0 3 3 3 3 FAD binding domain NAD_binding_8 PF13450.6 ORY07767.1 - 0.001 19.3 0.0 0.0024 18.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ORY07767.1 - 0.0019 17.5 0.0 0.005 16.1 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 ORY07767.1 - 0.018 14.1 0.0 0.029 13.4 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox PF00070.27 ORY07767.1 - 0.037 14.6 0.0 0.087 13.4 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ORY07767.1 - 0.099 11.7 0.0 0.32 10.0 0.0 1.7 2 0 0 2 2 2 0 FAD binding domain Beta-lactamase PF00144.24 ORY07768.1 - 5.7e-38 131.0 0.0 7.7e-38 130.5 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Snf7 PF03357.21 ORY07769.1 - 1.5e-24 86.5 12.4 1.5e-24 86.5 12.4 1.8 1 1 1 2 2 2 1 Snf7 Gon7 PF08738.10 ORY07769.1 - 0.0043 17.1 1.0 0.0043 17.1 1.0 2.3 2 0 0 2 2 2 1 Gon7 family DUF4172 PF13776.6 ORY07769.1 - 0.61 10.5 3.8 6.5 7.2 0.4 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4172) MerR-DNA-bind PF09278.11 ORY07769.1 - 0.69 10.5 11.6 1.8 9.2 0.3 3.4 3 0 0 3 3 3 0 MerR, DNA binding L31 PF09784.9 ORY07769.1 - 4.5 7.7 8.1 0.81 10.2 3.6 2.0 2 1 0 2 2 2 0 Mitochondrial ribosomal protein L31 CS PF04969.16 ORY07770.1 - 5e-08 33.9 0.0 7.5e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 CS domain AA_permease_2 PF13520.6 ORY07771.1 - 1.1e-51 176.0 50.2 1.4e-51 175.7 50.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ORY07771.1 - 8.6e-30 103.7 42.2 1.1e-29 103.4 42.2 1.0 1 0 0 1 1 1 1 Amino acid permease YlaH PF14036.6 ORY07771.1 - 5.9 7.3 12.2 0.097 13.0 1.1 2.9 3 0 0 3 3 3 0 YlaH-like protein Zn_clus PF00172.18 ORY07773.1 - 0.0048 17.0 6.8 0.015 15.5 6.8 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-BED PF02892.15 ORY07773.1 - 0.015 15.3 0.4 0.042 13.9 0.4 1.8 1 0 0 1 1 1 0 BED zinc finger DUF2236 PF09995.9 ORY07774.1 - 3e-06 27.6 0.2 5.3e-06 26.8 0.2 1.5 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) TPR_2 PF07719.17 ORY07775.1 - 5.9e-06 26.0 0.1 0.03 14.4 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 ORY07775.1 - 2e-05 24.2 0.0 0.018 14.9 0.0 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 ORY07775.1 - 0.00016 21.9 1.4 0.0003 21.0 0.4 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 ORY07775.1 - 0.00023 21.0 1.3 0.16 12.1 0.1 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 ORY07775.1 - 0.00059 19.5 0.1 0.0016 18.1 0.1 1.8 2 0 0 2 2 2 1 TPR repeat DUF3856 PF12968.7 ORY07775.1 - 0.016 15.3 2.1 0.85 9.7 0.3 2.5 1 1 1 2 2 2 0 Domain of Unknown Function (DUF3856) Cytotoxic PF09000.10 ORY07775.1 - 0.12 12.7 0.0 0.38 11.1 0.0 1.7 1 1 0 1 1 1 0 Cytotoxic TPR_14 PF13428.6 ORY07775.1 - 1.9 9.5 0.0 1.9 9.5 0.0 3.3 4 1 0 4 4 4 0 Tetratricopeptide repeat HAD_2 PF13419.6 ORY07776.1 - 5.8e-20 72.1 0.0 8.5e-20 71.6 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ORY07776.1 - 4.3e-11 43.5 0.0 8.1e-09 36.1 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ORY07776.1 - 0.00063 19.8 0.0 0.0022 18.0 0.0 1.9 3 0 0 3 3 3 1 HAD-hyrolase-like HAD PF12710.7 ORY07776.1 - 0.0066 16.9 0.0 0.013 15.9 0.0 1.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 ORY07776.1 - 0.094 12.8 0.1 1.3 9.2 0.1 2.3 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase UPF0020 PF01170.18 ORY07777.1 - 2.5e-08 33.8 0.2 3.6e-07 30.1 0.2 2.5 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 DUF4242 PF14026.6 ORY07777.1 - 0.2 11.8 0.0 0.39 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4242) Alpha-L-AF_C PF06964.12 ORY07778.1 - 3.2e-24 85.9 0.1 6.8e-24 84.9 0.1 1.6 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain MFS_1 PF07690.16 ORY07780.1 - 6.4e-40 137.2 60.8 3.5e-39 134.7 58.6 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 ORY07780.1 - 3.8e-15 55.4 20.4 4.7e-15 55.0 20.4 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 ORY07780.1 - 1.7e-11 43.7 15.5 1.7e-11 43.7 15.5 3.1 1 1 2 3 3 3 1 Sugar (and other) transporter OATP PF03137.20 ORY07780.1 - 0.026 12.8 13.6 0.11 10.7 3.2 2.5 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Patatin PF01734.22 ORY07783.1 - 5.2e-24 85.6 0.0 8e-24 84.9 0.0 1.3 1 0 0 1 1 1 1 Patatin-like phospholipase MFS_1 PF07690.16 ORY07784.1 - 1.6e-19 70.1 54.4 1.4e-12 47.3 24.1 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 ORY07784.1 - 0.0035 16.3 1.8 0.0035 16.3 1.8 2.0 1 1 0 2 2 2 1 MFS_1 like family SIR2 PF02146.17 ORY07786.1 - 3e-56 190.2 0.0 4.9e-56 189.4 0.0 1.4 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 ORY07786.1 - 0.00032 20.4 0.1 0.15 11.8 0.1 2.4 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain DUF592 PF04574.13 ORY07786.1 - 0.0004 20.2 0.0 0.00074 19.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF592) Ribonuc_P_40 PF08584.11 ORY07787.1 - 1.1e-68 231.7 0.0 1.4e-68 231.2 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit Nop53 PF07767.11 ORY07788.1 - 0.37 10.1 1.2 0.49 9.7 1.2 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Cu-oxidase_3 PF07732.15 ORY07790.1 - 1.5e-43 147.6 7.8 1.5e-41 141.2 1.1 3.0 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 ORY07790.1 - 3.1e-40 137.1 7.6 4.8e-38 130.0 0.4 4.0 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 ORY07790.1 - 2.4e-36 125.2 0.3 7.3e-36 123.7 0.3 1.9 1 0 0 1 1 1 1 Multicopper oxidase NARP1 PF12569.8 ORY07791.1 - 7.1e-200 665.3 9.2 7.1e-200 665.3 9.2 3.2 3 0 0 3 3 2 2 NMDA receptor-regulated protein 1 Fapy_DNA_glyco PF01149.24 ORY07791.1 - 1.5e-31 109.4 0.0 5.2e-31 107.7 0.0 2.0 2 0 0 2 2 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.14 ORY07791.1 - 6.3e-20 71.0 0.0 1.9e-19 69.5 0.0 1.7 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain TPR_19 PF14559.6 ORY07791.1 - 2.4e-15 56.8 24.2 0.01 16.4 0.1 6.9 6 0 0 6 6 6 5 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY07791.1 - 3.5e-12 46.4 20.3 0.00042 20.5 0.7 5.6 4 1 1 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 ORY07791.1 - 1e-10 41.6 5.2 0.0026 17.9 0.1 4.9 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 ORY07791.1 - 5.8e-10 39.1 26.7 0.064 14.1 1.2 10.2 7 4 5 12 12 10 4 Tetratricopeptide repeat TPR_2 PF07719.17 ORY07791.1 - 1.1e-09 37.7 30.4 0.001 19.0 0.1 9.5 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_16 PF13432.6 ORY07791.1 - 3.6e-09 37.1 31.0 0.0069 17.0 0.0 9.0 8 2 1 9 9 8 2 Tetratricopeptide repeat TPR_1 PF00515.28 ORY07791.1 - 4e-07 29.6 16.5 0.00021 21.0 0.0 7.3 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_11 PF13414.6 ORY07791.1 - 2.1e-06 27.3 9.4 0.00013 21.6 0.1 5.2 5 1 1 6 6 6 1 TPR repeat TPR_8 PF13181.6 ORY07791.1 - 6.2e-06 26.0 16.2 0.33 11.3 0.1 6.7 7 0 0 7 7 6 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 ORY07791.1 - 6.4e-06 26.1 6.2 1.2 9.2 0.0 5.6 5 0 0 5 5 5 1 Fis1 C-terminal tetratricopeptide repeat TPR_17 PF13431.6 ORY07791.1 - 9.6e-06 25.6 8.8 0.2 12.1 0.0 6.8 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 ORY07791.1 - 0.003 17.5 14.5 0.07 13.2 0.0 6.9 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_6 PF13174.6 ORY07791.1 - 0.0062 17.1 14.6 9.7 7.1 0.0 7.1 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_12 PF13424.6 ORY07791.1 - 0.03 14.6 29.4 0.51 10.7 0.8 7.1 6 2 2 8 8 8 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 ORY07791.1 - 0.072 13.5 6.6 14 6.1 0.3 4.4 4 0 0 4 4 4 0 Alkyl sulfatase dimerisation CCSAP PF15748.5 ORY07791.1 - 5.1 7.2 19.2 3 8.0 12.5 2.4 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated Arginase PF00491.21 ORY07792.1 - 2.7e-94 315.8 0.0 3.2e-94 315.5 0.0 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 ORY07792.1 - 0.0054 17.0 0.3 0.01 16.1 0.3 1.4 1 0 0 1 1 1 1 UPF0489 domain Tocopherol_cycl PF14249.6 ORY07793.1 - 5.5e-06 25.7 0.6 0.0068 15.6 0.2 3.0 2 1 0 3 3 3 3 Tocopherol cyclase AAA_12 PF13087.6 ORY07796.1 - 3.9e-37 127.8 0.0 6.8e-37 127.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 ORY07796.1 - 4.6e-21 75.8 0.4 4.6e-21 75.8 0.4 2.2 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 ORY07796.1 - 9.8e-08 32.5 0.0 5.6e-07 30.0 0.0 2.4 2 1 0 2 2 2 1 AAA domain DUF2075 PF09848.9 ORY07796.1 - 9.6e-07 28.4 0.2 0.0054 16.0 0.0 2.7 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 ORY07796.1 - 2.7e-06 27.2 0.3 0.0015 18.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain ResIII PF04851.15 ORY07796.1 - 0.00031 20.8 0.5 0.0051 16.8 0.0 2.7 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit PhoH PF02562.16 ORY07796.1 - 0.037 13.5 0.0 0.11 12.0 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein UvrD_C_2 PF13538.6 ORY07796.1 - 0.047 13.5 0.0 0.12 12.2 0.0 1.8 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA_22 PF13401.6 ORY07796.1 - 0.061 13.6 0.6 4.9 7.4 0.1 3.3 2 1 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 ORY07796.1 - 0.088 12.2 0.1 0.36 10.2 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DUF2783 PF10932.8 ORY07796.1 - 0.12 12.1 0.1 0.57 9.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2783) AAA_16 PF13191.6 ORY07796.1 - 0.14 12.5 0.1 11 6.3 0.0 3.2 2 1 0 2 2 2 0 AAA ATPase domain Glyco_hydro_88 PF07470.13 ORY07799.1 - 8e-68 229.0 3.3 9.7e-68 228.8 3.3 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 WD40 PF00400.32 ORY07800.1 - 1.3e-20 73.3 20.0 5.7e-06 27.0 0.3 6.9 6 2 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY07800.1 - 5.3e-13 49.1 8.7 1.6e-05 25.1 0.1 4.0 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain TFIIIC_delta PF12657.7 ORY07800.1 - 0.0098 15.8 12.4 0.11 12.5 0.3 3.8 1 1 0 2 2 2 2 Transcription factor IIIC subunit delta N-term AAA_11 PF13086.6 ORY07801.1 - 0.0094 15.8 0.0 0.0096 15.7 0.0 1.0 1 0 0 1 1 1 1 AAA domain F-box PF00646.33 ORY07802.1 - 7.6e-05 22.5 0.0 0.00016 21.4 0.0 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 ORY07802.1 - 0.031 14.2 0.0 0.063 13.2 0.0 1.5 1 0 0 1 1 1 0 F-box-like PRANC PF09372.10 ORY07802.1 - 0.12 12.7 0.0 0.78 10.1 0.0 2.1 2 0 0 2 2 2 0 PRANC domain GSDH PF07995.11 ORY07803.1 - 9.1e-06 25.2 1.1 5.1e-05 22.7 1.1 2.2 1 1 0 1 1 1 1 Glucose / Sorbosone dehydrogenase SGL PF08450.12 ORY07803.1 - 0.00066 19.3 0.0 0.056 13.0 0.0 2.6 2 1 0 2 2 2 2 SMP-30/Gluconolactonase/LRE-like region ABC_tran PF00005.27 ORY07805.1 - 2.2e-46 157.8 0.7 7e-22 78.4 0.0 3.3 3 0 0 3 3 3 2 ABC transporter ABC_tran_Xtn PF12848.7 ORY07805.1 - 6.2e-20 71.0 6.5 6.2e-20 71.0 6.5 2.8 4 0 0 4 4 2 1 ABC transporter AAA_21 PF13304.6 ORY07805.1 - 4.5e-17 62.8 4.5 0.00064 19.6 0.0 4.7 4 1 1 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ORY07805.1 - 5.1e-12 45.7 0.1 0.0078 15.7 0.0 4.4 4 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 ORY07805.1 - 7.2e-06 26.3 0.1 0.068 13.5 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_23 PF13476.6 ORY07805.1 - 7.9e-06 26.5 14.7 0.012 16.2 0.0 4.9 4 1 1 5 5 5 2 AAA domain AAA_30 PF13604.6 ORY07805.1 - 1.3e-05 25.0 0.1 0.0068 16.1 0.0 3.3 3 0 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.23 ORY07805.1 - 2.4e-05 24.4 0.0 0.046 13.8 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 ORY07805.1 - 2.9e-05 23.7 0.4 0.16 11.8 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_18 PF13238.6 ORY07805.1 - 3.3e-05 24.4 0.9 0.28 11.7 0.0 3.5 4 0 0 4 4 3 2 AAA domain AAA_16 PF13191.6 ORY07805.1 - 6.5e-05 23.4 0.8 0.035 14.5 0.3 2.7 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 ORY07805.1 - 6.7e-05 22.8 0.1 0.08 12.8 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_24 PF13479.6 ORY07805.1 - 0.00012 21.8 0.5 0.39 10.4 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_33 PF13671.6 ORY07805.1 - 0.00027 21.1 0.4 1.1 9.4 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_28 PF13521.6 ORY07805.1 - 0.00094 19.5 3.7 0.069 13.4 0.1 2.9 3 0 0 3 3 2 1 AAA domain AAA_15 PF13175.6 ORY07805.1 - 0.0011 18.7 10.5 0.27 10.9 0.0 4.4 3 1 0 3 3 3 1 AAA ATPase domain NACHT PF05729.12 ORY07805.1 - 0.0014 18.6 0.1 0.85 9.5 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_14 PF13173.6 ORY07805.1 - 0.0023 17.9 0.3 7.6 6.6 0.0 3.9 4 0 0 4 4 3 0 AAA domain AAA PF00004.29 ORY07805.1 - 0.0025 18.2 0.0 2.1 8.8 0.1 3.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 ORY07805.1 - 0.0063 16.9 0.0 3.4 8.1 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_27 PF13514.6 ORY07805.1 - 0.007 16.0 2.5 3.3 7.2 0.0 3.5 4 0 0 4 4 3 2 AAA domain MeaB PF03308.16 ORY07805.1 - 0.019 14.0 0.9 3.3 6.6 0.0 2.7 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB MobB PF03205.14 ORY07805.1 - 0.029 14.3 0.1 1.9 8.4 0.0 3.0 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 ORY07805.1 - 0.032 14.1 0.0 3.1 7.7 0.0 2.8 2 0 0 2 2 2 0 NTPase cobW PF02492.19 ORY07805.1 - 0.038 13.6 0.3 3.7 7.1 0.2 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.14 ORY07805.1 - 0.054 13.5 0.2 7.9 6.5 0.0 2.9 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) SRP54 PF00448.22 ORY07805.1 - 0.061 12.9 0.2 3.9 7.0 0.0 2.9 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain Roc PF08477.13 ORY07805.1 - 0.13 12.4 0.1 7.3 6.8 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase TsaE PF02367.17 ORY07805.1 - 0.14 12.2 0.0 26 4.8 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 ORY07805.1 - 0.16 11.5 0.0 22 4.5 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region Zeta_toxin PF06414.12 ORY07805.1 - 0.27 10.5 2.9 9.9 5.4 0.1 2.7 3 0 0 3 3 3 0 Zeta toxin Dynamin_N PF00350.23 ORY07805.1 - 0.38 10.8 4.5 2.3 8.3 0.0 3.3 2 1 0 3 3 3 0 Dynamin family AAA_17 PF13207.6 ORY07805.1 - 5.7 7.4 5.8 50 4.3 0.2 3.6 4 0 0 4 4 3 0 AAA domain DUF924 PF06041.11 ORY07807.1 - 8e-47 159.7 0.0 1.3e-46 159.0 0.0 1.3 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF924) Amidase PF01425.21 ORY07899.1 - 7.5e-30 104.3 0.2 1.2e-29 103.6 0.2 1.2 1 0 0 1 1 1 1 Amidase TFIIA PF03153.13 ORY07900.1 - 2.1 8.2 26.8 2.9 7.8 26.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DIOX_N PF14226.6 ORY07901.1 - 1.5e-31 109.6 0.0 2.1e-31 109.1 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 ORY07901.1 - 1.3e-16 60.9 0.1 2.8e-16 59.8 0.1 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF1996 PF09362.10 ORY07902.1 - 2.3e-82 276.5 1.9 3e-82 276.1 1.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Methyltransf_11 PF08241.12 ORY07903.1 - 2.2e-09 37.8 0.0 3.5e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY07903.1 - 1.7e-07 31.8 0.0 4.1e-07 30.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY07903.1 - 3.4e-06 26.9 0.0 4.2e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY07903.1 - 0.0063 17.2 0.0 0.011 16.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ank_2 PF12796.7 ORY07904.1 - 3.4e-12 46.8 0.0 0.00095 19.7 0.0 4.8 2 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ORY07904.1 - 4.2e-11 42.9 0.0 0.19 12.1 0.0 4.8 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 ORY07904.1 - 1.5e-06 28.6 0.0 0.22 12.1 0.0 4.3 4 1 0 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY07904.1 - 9.3e-06 25.6 0.0 28 5.7 0.0 6.1 5 0 0 5 5 5 0 Ankyrin repeat AAA_16 PF13191.6 ORY07904.1 - 6.8e-05 23.3 0.0 0.00036 21.0 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 ORY07904.1 - 0.00011 22.2 0.0 0.00031 20.7 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 ORY07904.1 - 0.00069 19.9 0.0 0.0037 17.5 0.0 2.3 3 0 0 3 3 3 1 AAA domain DUF4781 PF16013.5 ORY07905.1 - 0.0013 17.6 0.1 0.0019 17.1 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4781) PT-VENN PF04829.13 ORY07905.1 - 1.4 9.1 3.5 2.9 8.0 3.5 1.5 1 0 0 1 1 1 0 Pre-toxin domain with VENN motif Malate_synthase PF01274.22 ORY07906.1 - 1.2e-230 766.3 0.0 1.3e-230 766.1 0.0 1.0 1 0 0 1 1 1 1 Malate synthase VSP PF03302.13 ORY07907.1 - 4.7e-05 22.4 0.2 6e-05 22.1 0.2 1.2 1 0 0 1 1 1 1 Giardia variant-specific surface protein DUF4394 PF14339.6 ORY07910.1 - 0.015 14.6 3.2 0.14 11.5 0.0 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4394) MBOAT_2 PF13813.6 ORY07911.1 - 2.3e-18 66.2 1.5 3.1e-18 65.8 0.4 1.8 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family Nup96 PF12110.8 ORY07912.1 - 0.035 13.2 0.1 0.054 12.6 0.1 1.2 1 0 0 1 1 1 0 Nuclear protein 96 Melibiase_2 PF16499.5 ORY07913.1 - 3.1e-59 200.5 1.2 5.4e-59 199.7 1.2 1.4 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 ORY07913.1 - 4.5e-14 52.3 0.0 1e-13 51.2 0.0 1.6 1 0 0 1 1 1 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 ORY07913.1 - 1.2e-05 24.4 0.0 2.1e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Melibiase Glyco_hydro_97 PF10566.9 ORY07913.1 - 2.4e-05 23.8 0.0 3.5e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Glycoside hydrolase 97 Phospholip_A2_2 PF05826.12 ORY07913.1 - 0.057 13.6 1.3 0.12 12.7 1.3 1.4 1 0 0 1 1 1 0 Phospholipase A2 Melibiase_2_C PF17450.2 ORY07913.1 - 0.17 12.2 0.0 0.36 11.1 0.0 1.7 1 0 0 1 1 1 0 Alpha galactosidase A C-terminal beta sandwich domain VWA PF00092.28 ORY07916.1 - 3.2e-12 47.0 0.6 7.8e-12 45.8 0.6 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 ORY07916.1 - 2.7e-11 44.1 0.1 5.7e-11 43.0 0.1 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 ORY07916.1 - 0.00012 21.5 0.0 0.0043 16.5 0.0 2.1 2 0 0 2 2 2 1 VWA domain containing CoxE-like protein EMP24_GP25L PF01105.24 ORY07916.1 - 0.031 14.2 0.1 0.053 13.5 0.1 1.3 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Glyco_transf_43 PF03360.16 ORY07916.1 - 0.2 11.5 0.0 0.32 10.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 43 MARVEL PF01284.23 ORY07917.1 - 1.6e-08 34.7 16.6 7.1e-08 32.6 15.7 1.9 1 1 1 2 2 2 1 Membrane-associating domain PIG-P PF08510.12 ORY07917.1 - 1.1 9.1 14.1 0.22 11.5 5.0 2.4 3 0 0 3 3 3 0 PIG-P DUF805 PF05656.14 ORY07917.1 - 3.4 8.1 8.0 0.62 10.5 3.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF805) SMC_N PF02463.19 ORY07918.1 - 5.8e-22 78.2 9.2 1.8e-21 76.6 9.1 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 ORY07918.1 - 5.5e-16 59.7 25.2 5.5e-16 59.7 25.2 5.9 2 2 1 3 3 3 1 AAA domain AAA_15 PF13175.6 ORY07918.1 - 1e-07 32.1 34.4 6.4e-07 29.4 0.1 3.4 2 2 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 ORY07918.1 - 1.4e-06 28.3 1.1 0.012 15.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 ORY07918.1 - 7.1e-05 22.5 0.0 0.00015 21.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ZapB PF06005.12 ORY07918.1 - 0.011 16.2 3.7 0.011 16.2 3.7 8.0 5 2 1 6 6 6 0 Cell division protein ZapB ABC_tran PF00005.27 ORY07918.1 - 0.03 14.8 0.1 0.03 14.8 0.1 4.8 3 2 0 3 3 3 0 ABC transporter AAA_27 PF13514.6 ORY07918.1 - 0.043 13.4 0.0 0.043 13.4 0.0 4.8 5 2 0 5 5 5 0 AAA domain AAA_25 PF13481.6 ORY07918.1 - 0.31 10.6 4.2 0.41 10.2 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA PF00004.29 ORY07918.1 - 0.36 11.2 3.5 0.42 11.0 0.0 3.0 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Lyase_1 PF00206.20 ORY07919.1 - 2.9e-111 371.8 0.0 4.1e-111 371.3 0.0 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 ORY07919.1 - 1.8e-20 73.1 0.1 5.6e-20 71.5 0.1 2.0 1 0 0 1 1 1 1 Fumarase C C-terminus zf-RING_2 PF13639.6 ORY07921.1 - 1.5e-08 34.8 10.0 2.8e-08 34.0 10.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 ORY07921.1 - 4.2e-07 30.2 11.1 7.3e-07 29.4 11.1 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 ORY07921.1 - 1.2e-06 28.5 2.6 2.2e-06 27.6 2.6 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 ORY07921.1 - 2.7e-05 24.1 7.0 2.8e-05 24.0 5.7 1.8 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 ORY07921.1 - 3.9e-05 23.4 11.4 6e-05 22.8 11.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORY07921.1 - 0.00018 21.4 10.2 0.00029 20.7 10.2 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 ORY07921.1 - 0.013 15.7 4.5 0.29 11.3 5.3 2.4 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 ORY07921.1 - 0.019 14.8 10.4 0.13 12.1 10.0 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Pellino PF04710.14 ORY07921.1 - 0.072 11.7 0.4 0.11 11.1 0.4 1.2 1 0 0 1 1 1 0 Pellino zf-C3HC4_3 PF13920.6 ORY07921.1 - 0.088 12.7 9.5 0.23 11.3 9.5 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 ORY07921.1 - 0.11 12.3 2.6 0.32 10.8 2.6 1.9 1 1 0 1 1 1 0 RING-like zinc finger zf-C3HC4_2 PF13923.6 ORY07921.1 - 0.89 9.4 13.0 6.7 6.6 13.1 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 ORY07921.1 - 1.2 9.4 5.9 2.2 8.5 5.9 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 ORY07921.1 - 1.2 8.8 5.1 3.3 7.4 5.1 1.8 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Pkinase PF00069.25 ORY07922.1 - 2.3e-60 204.2 0.0 1.5e-59 201.5 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY07922.1 - 1e-28 100.4 0.2 4e-20 72.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.24 ORY07922.1 - 0.00021 21.9 0.3 0.00094 19.8 0.3 2.2 1 0 0 1 1 1 1 Protein kinase C terminal domain APH PF01636.23 ORY07922.1 - 0.00053 20.0 3.8 0.12 12.3 0.1 3.3 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.6 ORY07922.1 - 0.00058 19.3 0.7 0.003 16.9 0.0 2.3 3 0 0 3 3 3 1 Kinase-like Haspin_kinase PF12330.8 ORY07922.1 - 0.0048 15.9 0.0 0.018 14.0 0.0 1.8 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 ORY07922.1 - 0.024 14.0 0.0 0.072 12.4 0.0 1.8 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family GMC_oxred_N PF00732.19 ORY07924.1 - 3e-52 177.8 0.0 5e-52 177.1 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 ORY07924.1 - 1.9e-37 129.0 0.1 3.4e-37 128.1 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 ORY07924.1 - 1.6e-06 27.5 1.8 0.029 13.5 1.6 2.3 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 ORY07924.1 - 5.2e-06 26.3 0.2 2e-05 24.4 0.2 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 ORY07924.1 - 3.8e-05 23.1 0.3 0.12 11.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORY07924.1 - 0.0072 16.5 2.4 0.024 14.8 2.4 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 ORY07924.1 - 0.0097 15.0 0.2 0.015 14.4 0.2 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 ORY07924.1 - 0.014 14.7 1.0 0.032 13.5 1.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 ORY07924.1 - 0.017 14.0 0.1 0.024 13.5 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Thi4 PF01946.17 ORY07924.1 - 0.086 12.1 0.2 0.16 11.2 0.2 1.3 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.14 ORY07924.1 - 0.29 9.8 1.0 0.58 8.8 0.7 1.6 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox PF00070.27 ORY07924.1 - 0.34 11.5 1.8 1.3 9.7 0.9 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF3632 PF12311.8 ORY07926.1 - 8.9e-34 117.4 0.5 1.3e-33 116.9 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) YmzC PF14157.6 ORY07927.1 - 0.045 13.8 0.0 0.086 12.9 0.0 1.4 1 0 0 1 1 1 0 YmzC-like protein p450 PF00067.22 ORY07929.1 - 5.2e-67 226.6 0.0 7e-67 226.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 VIT PF08487.10 ORY07930.1 - 6.1e-31 106.9 0.0 1.2e-30 105.9 0.0 1.5 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_3 PF13768.6 ORY07930.1 - 1.8e-22 80.0 0.0 6.6e-22 78.1 0.0 1.9 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.28 ORY07930.1 - 6.5e-10 39.5 0.0 1.1e-09 38.8 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 ORY07930.1 - 4.4e-08 33.7 0.0 9e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT_2 PF13757.6 ORY07930.1 - 1e-06 28.5 0.0 1.9e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_CoxE PF05762.14 ORY07930.1 - 0.0024 17.3 0.0 0.0042 16.5 0.0 1.3 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein Varsurf_PPLC PF03490.13 ORY07930.1 - 0.032 14.2 0.1 0.12 12.3 0.1 1.9 1 0 0 1 1 1 0 Variant-surface-glycoprotein phospholipase C SesA PF17107.5 ORY07931.1 - 0.0014 18.8 0.0 0.0062 16.7 0.0 2.1 1 1 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases DUF948 PF06103.11 ORY07931.1 - 0.04 14.2 2.8 2.1 8.6 0.1 3.0 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Syntaxin-6_N PF09177.11 ORY07931.1 - 0.76 10.4 5.5 0.74 10.4 2.0 2.8 3 1 0 3 3 3 0 Syntaxin 6, N-terminal FliD_N PF02465.18 ORY07931.1 - 4 8.2 4.8 2.1 9.1 0.2 2.8 3 0 0 3 3 3 0 Flagellar hook-associated protein 2 N-terminus Glyco_hydro_45 PF02015.16 ORY07932.1 - 7.4e-72 241.7 16.7 8.6e-72 241.5 16.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 Pex14_N PF04695.13 ORY07933.1 - 0.047 14.4 1.1 0.058 14.0 1.1 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Nuc_deoxyrib_tr PF05014.15 ORY07933.1 - 0.23 11.5 0.4 19 5.3 0.0 2.1 2 0 0 2 2 2 0 Nucleoside 2-deoxyribosyltransferase DUF1772 PF08592.11 ORY07934.1 - 3.1e-05 24.3 0.1 4.8e-05 23.7 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) Vma12 PF11712.8 ORY07935.1 - 0.18 11.8 0.4 10 6.2 0.0 2.5 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase MFS_1 PF07690.16 ORY07936.1 - 9.2e-27 93.9 13.5 9.2e-27 93.9 13.5 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY07936.1 - 3.2e-11 42.8 3.3 3.2e-11 42.8 3.3 2.6 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 ORY07936.1 - 9e-06 24.4 3.1 1.4e-05 23.8 3.1 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) NmrA PF05368.13 ORY07938.1 - 7.5e-13 48.6 0.0 1.1e-12 48.1 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ORY07938.1 - 8.5e-07 29.0 0.0 1.8e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding Fungal_trans PF04082.18 ORY07939.1 - 2.8e-23 82.3 0.0 4.1e-23 81.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY07939.1 - 1.9e-08 34.3 9.8 3.6e-08 33.4 9.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DoxX_2 PF13564.6 ORY07939.1 - 0.033 14.3 0.1 2.3 8.4 0.0 2.8 3 0 0 3 3 3 0 DoxX-like family SLATT_1 PF18181.1 ORY07939.1 - 0.093 12.7 0.3 0.48 10.4 0.1 2.2 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 Amidoligase_2 PF12224.8 ORY07939.1 - 0.15 11.7 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 Putative amidoligase enzyme p450 PF00067.22 ORY07940.1 - 9.7e-73 245.5 0.0 1.3e-72 245.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Luciferase_N PF05295.11 ORY07941.1 - 0.17 11.9 0.1 0.75 9.9 0.1 2.0 1 1 0 1 1 1 0 Luciferase/LBP N-terminal domain Glyco_hydro_28 PF00295.17 ORY07942.1 - 4.2e-08 32.6 0.5 4e-05 22.9 0.0 2.5 2 0 0 2 2 2 2 Glycosyl hydrolases family 28 Pectate_lyase_3 PF12708.7 ORY07942.1 - 0.021 14.7 1.1 2 8.2 0.0 2.8 2 1 1 3 3 3 0 Pectate lyase superfamily protein DUF5109 PF17134.4 ORY07942.1 - 0.052 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5109) Cutinase PF01083.22 ORY07944.1 - 3.8e-48 163.8 1.5 4.8e-48 163.5 1.5 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 ORY07944.1 - 9.5e-06 25.3 0.8 1.2e-05 25.0 0.2 1.5 2 0 0 2 2 2 1 PE-PPE domain VirJ PF06057.11 ORY07944.1 - 7e-05 22.8 0.0 0.00074 19.4 0.0 2.0 1 1 1 2 2 2 1 Bacterial virulence protein (VirJ) DUF2974 PF11187.8 ORY07944.1 - 0.0017 18.0 0.3 0.0033 17.0 0.3 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_2 PF02230.16 ORY07944.1 - 0.014 15.2 0.0 0.024 14.4 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Methyltransf_31 PF13847.6 ORY07945.1 - 2.1e-27 95.8 0.0 3e-27 95.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY07945.1 - 1.5e-24 86.5 0.0 2.5e-24 85.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY07945.1 - 2.8e-24 85.7 0.0 4.7e-24 84.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORY07945.1 - 4.1e-18 65.6 0.0 5.7e-18 65.1 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 ORY07945.1 - 3e-17 63.2 0.0 4.3e-17 62.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY07945.1 - 3.5e-15 56.2 0.0 5e-15 55.7 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 ORY07945.1 - 3.3e-08 33.5 0.0 4.5e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.12 ORY07945.1 - 7.5e-06 25.7 0.0 1.8e-05 24.4 0.0 1.5 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.14 ORY07945.1 - 9.7e-06 25.2 0.0 1.7e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 ORY07945.1 - 2.3e-05 24.0 0.0 6.4e-05 22.5 0.0 1.7 2 1 0 2 2 2 1 Putative methyltransferase Methyltransf_2 PF00891.18 ORY07945.1 - 0.00017 21.0 0.0 0.00023 20.5 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_9 PF08003.11 ORY07945.1 - 0.00017 20.7 0.0 0.00033 19.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_29 PF03141.16 ORY07945.1 - 0.0003 19.5 0.0 0.0005 18.7 0.0 1.3 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase CheR PF01739.18 ORY07945.1 - 0.0018 17.8 0.0 0.071 12.6 0.0 2.3 1 1 1 2 2 2 1 CheR methyltransferase, SAM binding domain Methyltransf_18 PF12847.7 ORY07945.1 - 0.0077 16.2 0.0 0.012 15.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 ORY07945.1 - 0.014 15.0 0.0 0.022 14.4 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_32 PF13679.6 ORY07945.1 - 0.023 14.7 0.0 0.035 14.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.20 ORY07945.1 - 0.073 12.4 0.0 0.091 12.0 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase FtsJ PF01728.19 ORY07945.1 - 0.14 12.2 0.0 0.31 11.1 0.0 1.5 2 0 0 2 2 2 0 FtsJ-like methyltransferase DUF2335 PF10097.9 ORY07946.1 - 0.069 13.1 0.0 0.78 9.7 0.0 2.9 1 0 0 1 1 1 0 Predicted membrane protein (DUF2335) Rsa3 PF14615.6 ORY07946.1 - 0.12 12.0 3.3 0.14 11.7 0.0 2.9 3 0 0 3 3 3 0 Ribosome-assembly protein 3 MCC-bdg_PDZ PF10506.9 ORY07946.1 - 5.1 7.2 7.1 46 4.1 0.0 3.6 2 1 1 3 3 3 0 PDZ domain of MCC-2 bdg protein for Usher syndrome DNA_pack_N PF02500.15 ORY07946.1 - 6.5 6.5 7.7 39 3.9 0.1 3.4 3 0 0 3 3 3 0 Probable DNA packing protein, N-terminus DUF1664 PF07889.12 ORY07947.1 - 0.0093 16.0 0.6 0.014 15.4 0.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) XhlA PF10779.9 ORY07947.1 - 0.015 15.5 0.1 5.1 7.4 0.1 2.4 2 0 0 2 2 2 0 Haemolysin XhlA DivIC PF04977.15 ORY07947.1 - 0.063 13.0 0.6 1.2 9.0 0.2 2.2 1 1 1 2 2 2 0 Septum formation initiator Baculo_PEP_C PF04513.12 ORY07947.1 - 0.067 13.2 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1018 PF06252.12 ORY07947.1 - 0.1 13.6 0.1 0.28 12.2 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) BLOC1_2 PF10046.9 ORY07947.1 - 0.11 12.9 0.3 11 6.4 0.1 2.2 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Csm1_N PF18504.1 ORY07947.1 - 0.13 12.6 0.6 1.8 9.0 0.2 2.2 2 0 0 2 2 2 0 Csm1 N-terminal domain DASH_Dad2 PF08654.10 ORY07947.1 - 0.22 12.0 1.1 2.3 8.7 0.3 2.3 2 0 0 2 2 2 0 DASH complex subunit Dad2 AKNA PF12443.8 ORY07947.1 - 1.3 9.7 7.6 1.9 9.2 1.3 3.0 2 1 1 3 3 3 0 AT-hook-containing transcription factor TPR_12 PF13424.6 ORY07948.1 - 1.6e-18 66.8 9.9 2.7e-10 40.4 0.9 3.0 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.6 ORY07948.1 - 1.8e-16 59.4 9.2 7.5e-09 35.2 0.1 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat NB-ARC PF00931.22 ORY07948.1 - 0.046 12.9 0.0 0.11 11.7 0.0 1.7 1 0 0 1 1 1 0 NB-ARC domain TPR_7 PF13176.6 ORY07948.1 - 1.1 9.4 3.4 17 5.7 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat EHN PF06441.12 ORY07950.1 - 1.4e-26 93.0 0.3 2.8e-26 92.0 0.3 1.5 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 ORY07950.1 - 4e-07 30.0 0.1 7.1e-07 29.1 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORY07950.1 - 3.6e-06 27.7 2.6 5.2e-06 27.2 0.5 2.1 2 1 0 2 2 2 1 Alpha/beta hydrolase family fn3_2 PF16893.5 ORY07951.1 - 1.1e-36 124.8 0.2 1.7e-36 124.2 0.2 1.3 1 0 0 1 1 1 1 Fibronectin type III domain CHS5_N PF16892.5 ORY07951.1 - 7e-24 83.5 0.6 1.1e-23 82.9 0.6 1.3 1 0 0 1 1 1 1 Chitin biosynthesis protein CHS5 N-terminus PTCB-BRCT PF12738.7 ORY07951.1 - 2.2e-15 56.3 0.0 4e-15 55.5 0.0 1.4 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 ORY07951.1 - 3e-08 33.9 0.0 6.6e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DUF3006 PF11213.8 ORY07951.1 - 4e-05 23.8 0.0 0.00014 22.0 0.0 2.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3006) fn3 PF00041.21 ORY07951.1 - 0.0011 19.3 0.6 0.0028 18.0 0.1 2.0 2 1 0 2 2 2 1 Fibronectin type III domain BRCT_2 PF16589.5 ORY07951.1 - 0.0016 18.8 0.0 0.0032 17.8 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain DUF1297 PF06973.12 ORY07951.1 - 0.14 11.7 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1297) Mg_trans_NIPA PF05653.14 ORY07952.1 - 9.4e-18 64.3 8.2 1.3e-17 63.9 8.2 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 ORY07952.1 - 3.4e-05 24.0 18.8 0.0007 19.8 0.0 3.2 2 1 0 2 2 2 1 EamA-like transporter family PUNUT PF16913.5 ORY07952.1 - 0.0067 15.7 10.9 0.022 14.0 10.3 2.0 2 1 0 2 2 2 1 Purine nucleobase transmembrane transport TMEM61 PF15105.6 ORY07952.1 - 0.14 12.0 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 TMEM61 protein family DUF4131 PF13567.6 ORY07952.1 - 2.8 7.6 17.9 0.12 12.0 0.4 3.9 2 2 2 4 4 4 0 Domain of unknown function (DUF4131) vATP-synt_E PF01991.18 ORY07953.1 - 1.7e-66 223.4 9.3 2e-66 223.2 9.3 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit Med3 PF11593.8 ORY07953.1 - 0.04 13.1 1.2 0.048 12.8 1.2 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF885 PF05960.11 ORY07953.1 - 0.89 9.1 6.1 1.2 8.7 6.1 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) EutQ PF06249.12 ORY07954.1 - 1.2e-10 41.3 0.0 1.6e-10 41.0 0.0 1.1 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Cupin_3 PF05899.12 ORY07954.1 - 5.2e-08 32.5 0.1 7.2e-08 32.0 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_2 PF07883.11 ORY07954.1 - 0.0012 18.5 0.1 0.0018 18.0 0.1 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 ORY07954.1 - 0.063 12.9 0.0 0.1 12.2 0.0 1.3 1 1 0 1 1 1 0 Cupin GFO_IDH_MocA_C PF02894.17 ORY07955.1 - 2.7e-18 66.1 0.1 6.9e-18 64.7 0.1 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain GFO_IDH_MocA PF01408.22 ORY07955.1 - 7.7e-17 62.2 0.0 1.4e-16 61.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold MFS_1 PF07690.16 ORY07956.1 - 4.6e-18 65.3 12.5 5.6e-18 65.0 12.5 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily YrhK PF14145.6 ORY07956.1 - 0.014 15.2 9.3 0.45 10.4 0.3 3.4 1 1 1 3 3 3 0 YrhK-like protein TOM20_plant PF06552.12 ORY07956.1 - 0.15 11.7 0.2 0.25 11.0 0.2 1.2 1 0 0 1 1 1 0 Plant specific mitochondrial import receptor subunit TOM20 TPR_12 PF13424.6 ORY08034.1 - 8.2e-128 416.9 45.8 1.2e-20 73.5 1.6 8.0 1 1 9 10 10 10 10 Tetratricopeptide repeat TPR_10 PF13374.6 ORY08034.1 - 2.7e-111 360.9 13.9 6.9e-12 44.8 0.0 11.5 11 0 0 11 11 11 10 Tetratricopeptide repeat TPR_7 PF13176.6 ORY08034.1 - 9.1e-32 106.7 13.0 0.0043 17.0 0.1 9.7 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_1 PF00515.28 ORY08034.1 - 8.8e-27 91.8 12.9 0.0086 15.9 0.1 10.0 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_14 PF13428.6 ORY08034.1 - 3.2e-24 83.5 10.4 0.038 14.8 0.0 10.5 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_8 PF13181.6 ORY08034.1 - 1.7e-16 59.0 10.3 1.9 8.9 0.0 9.3 9 0 0 9 9 8 5 Tetratricopeptide repeat TPR_4 PF07721.14 ORY08034.1 - 1.2e-15 56.4 1.6 0.78 10.6 0.0 9.9 10 0 0 10 10 9 1 Tetratricopeptide repeat TPR_2 PF07719.17 ORY08034.1 - 5.7e-15 54.2 18.2 0.67 10.2 0.1 10.4 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_16 PF13432.6 ORY08034.1 - 9e-15 55.0 18.5 0.0042 17.7 2.7 8.1 4 2 3 7 7 7 5 Tetratricopeptide repeat TPR_MalT PF17874.1 ORY08034.1 - 1.3e-11 44.4 30.8 3.8e-07 29.8 1.1 4.3 3 1 3 6 6 6 4 MalT-like TPR region ANAPC3 PF12895.7 ORY08034.1 - 2.4e-09 37.3 0.0 0.055 13.7 0.0 7.1 2 1 4 6 6 5 2 Anaphase-promoting complex, cyclosome, subunit 3 NB-ARC PF00931.22 ORY08034.1 - 2.3e-08 33.6 0.0 0.00092 18.5 0.0 2.3 2 0 0 2 2 2 2 NB-ARC domain TPR_17 PF13431.6 ORY08034.1 - 3.6e-08 33.2 1.1 44 4.8 0.0 8.9 10 0 0 10 10 10 0 Tetratricopeptide repeat TPR_19 PF14559.6 ORY08034.1 - 1.4e-07 32.0 12.5 0.37 11.3 0.5 7.2 5 2 3 8 8 8 4 Tetratricopeptide repeat NRBF2_MIT PF17169.4 ORY08034.1 - 1.6e-07 31.4 2.6 20 5.5 0.0 8.0 8 0 0 8 8 8 0 MIT domain of nuclear receptor-binding factor 2 PPR PF01535.20 ORY08034.1 - 3.3e-05 23.9 6.6 19 5.8 0.0 7.2 8 0 0 8 8 8 0 PPR repeat DUF676 PF05057.14 ORY08034.1 - 0.00023 20.8 0.0 0.0011 18.5 0.0 2.1 2 0 0 2 2 2 1 Putative serine esterase (DUF676) nec1 PF10379.9 ORY08034.1 - 0.00043 19.8 0.0 2.8 7.4 0.0 4.5 2 2 3 5 5 5 1 Virulence protein nec1 AAA_22 PF13401.6 ORY08034.1 - 0.00061 20.1 0.0 0.003 17.9 0.0 2.2 2 0 0 2 2 1 1 AAA domain PGAP1 PF07819.13 ORY08034.1 - 0.0017 18.1 0.2 0.0083 15.9 0.0 2.2 2 1 0 2 2 2 1 PGAP1-like protein AAA_16 PF13191.6 ORY08034.1 - 0.014 15.8 3.0 0.029 14.8 0.9 2.8 2 1 0 2 2 2 0 AAA ATPase domain TPR_9 PF13371.6 ORY08034.1 - 0.016 15.4 2.7 7.2 6.8 0.2 5.2 4 2 3 7 7 6 0 Tetratricopeptide repeat AAA_25 PF13481.6 ORY08034.1 - 0.044 13.4 0.0 0.12 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain BTAD PF03704.17 ORY08034.1 - 0.17 12.3 12.9 8.5 6.8 0.3 5.1 2 2 3 5 5 5 0 Bacterial transcriptional activator domain TPR_21 PF09976.9 ORY08034.1 - 1.8 8.2 7.8 32 4.2 0.2 5.2 1 1 3 5 5 5 0 Tetratricopeptide repeat-like domain TPR_11 PF13414.6 ORY08034.1 - 3.3 7.5 15.7 69 3.2 0.0 7.0 7 0 0 7 7 7 0 TPR repeat CHRD PF07452.12 ORY08035.1 - 7.2e-13 49.5 0.2 8.9e-13 49.2 0.2 1.1 1 0 0 1 1 1 1 CHRD domain HET PF06985.11 ORY08036.1 - 2.8e-21 76.4 0.0 3.5e-21 76.1 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) E1-E2_ATPase PF00122.20 ORY08037.1 - 1e-35 122.9 19.5 7.6e-30 103.8 0.8 4.1 4 0 0 4 4 4 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 ORY08037.1 - 1.8e-23 83.2 6.5 1.8e-23 83.2 6.5 2.9 3 1 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 ORY08037.1 - 3e-17 63.6 0.0 1e-12 48.8 0.0 2.8 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 ORY08037.1 - 1.5e-13 50.2 0.3 3.5e-13 49.0 0.0 1.8 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 ORY08037.1 - 1.3e-10 41.2 0.0 3.3e-10 39.9 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 ORY08037.1 - 0.0068 16.2 1.2 0.012 15.4 1.2 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase CoA_binding_3 PF13727.6 ORY08037.1 - 0.6 10.1 4.1 4.1 7.4 0.4 3.0 2 1 1 3 3 3 0 CoA-binding domain Na_H_Exchanger PF00999.21 ORY08038.1 - 4.1e-40 137.8 18.2 5.8e-40 137.3 18.2 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.6 ORY08038.1 - 0.00037 20.5 3.6 0.00091 19.3 0.3 3.2 3 0 0 3 3 3 1 YrhC-like protein zf-3CxxC PF13695.6 ORY08039.1 - 5.2e-11 42.9 0.2 5.6e-11 42.8 0.2 1.0 1 0 0 1 1 1 1 Zinc-binding domain PAC4 PF16093.5 ORY08039.1 - 0.088 13.0 0.0 0.095 12.9 0.0 1.2 1 0 0 1 1 1 0 Proteasome assembly chaperone 4 DUF35_N PF12172.8 ORY08039.1 - 0.14 12.1 0.5 0.14 12.1 0.5 2.4 3 0 0 3 3 3 0 Rubredoxin-like zinc ribbon domain (DUF35_N) zf_C2H2_13 PF18508.1 ORY08039.1 - 0.18 11.4 0.0 0.18 11.4 0.0 2.7 3 0 0 3 3 3 0 Zinc finger domain Dimer_Tnp_hAT PF05699.14 ORY08040.1 - 0.00012 21.8 0.1 0.00014 21.6 0.1 1.3 1 1 0 1 1 1 1 hAT family C-terminal dimerisation region BolA PF01722.18 ORY08040.1 - 0.085 13.1 0.0 0.1 12.9 0.0 1.1 1 0 0 1 1 1 0 BolA-like protein CFEM PF05730.11 ORY08041.1 - 0.011 15.9 4.2 0.018 15.1 4.2 1.3 1 0 0 1 1 1 0 CFEM domain ANAPC5 PF12862.7 ORY08042.1 - 0.17 12.0 0.0 0.35 11.0 0.0 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 5 AAA_28 PF13521.6 ORY08043.1 - 1.6e-32 113.0 0.0 1.9e-32 112.8 0.0 1.0 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 ORY08043.1 - 0.00067 19.9 0.0 0.0011 19.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ORY08043.1 - 0.00082 19.8 0.0 0.0011 19.4 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 ORY08043.1 - 0.0027 17.9 0.0 0.031 14.4 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 ORY08043.1 - 0.0035 17.9 0.0 0.0058 17.2 0.0 1.5 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 ORY08043.1 - 0.0064 17.0 0.0 0.0082 16.7 0.0 1.2 1 0 0 1 1 1 1 ABC transporter TniB PF05621.11 ORY08043.1 - 0.032 13.6 0.0 0.062 12.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein MMR_HSR1 PF01926.23 ORY08043.1 - 0.076 13.1 0.0 0.22 11.6 0.0 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase Roc PF08477.13 ORY08043.1 - 0.087 13.0 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 ORY08043.1 - 0.15 11.8 0.0 0.42 10.4 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain dNK PF01712.19 ORY08043.1 - 0.15 11.9 0.0 0.69 9.7 0.0 1.9 1 1 0 1 1 1 0 Deoxynucleoside kinase DUF2048 PF09752.9 ORY08045.1 - 0.19 10.8 0.1 0.95 8.5 0.0 1.8 2 0 0 2 2 2 0 Abhydrolase domain containing 18 F-box-like PF12937.7 ORY08046.1 - 2e-07 30.8 0.0 5.5e-07 29.4 0.0 1.8 1 0 0 1 1 1 1 F-box-like Metallophos PF00149.28 ORY08047.1 - 2.3e-13 51.1 0.0 3.3e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 ORY08047.1 - 2e-07 31.3 0.0 0.0007 19.8 0.0 2.8 2 1 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain NPP1 PF05630.11 ORY08048.1 - 2.6e-61 207.2 0.0 3e-61 207.0 0.0 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) Bap31_Bap29_C PF18035.1 ORY08049.1 - 0.027 14.5 1.7 0.027 14.5 1.7 2.4 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain MT PF12777.7 ORY08049.1 - 0.066 12.2 0.9 0.47 9.4 0.9 2.2 2 0 0 2 2 2 0 Microtubule-binding stalk of dynein motor CRA PF06589.11 ORY08049.1 - 0.23 11.6 9.6 0.037 14.1 1.5 2.7 3 0 0 3 3 3 0 Circumsporozoite-related antigen (CRA) HalX PF08663.10 ORY08049.1 - 0.76 10.1 11.3 4.9 7.5 1.8 3.4 2 1 1 3 3 3 0 HalX domain AAA_23 PF13476.6 ORY08049.1 - 1.1 9.8 17.2 0.65 10.5 10.6 2.4 2 1 0 2 2 2 0 AAA domain SPATIAL PF15256.6 ORY08049.1 - 3.2 8.0 8.9 0.8 10.0 3.9 2.3 1 1 1 2 2 2 0 SPATIAL Lectin_N PF03954.14 ORY08049.1 - 3.9 7.2 7.8 7.1 6.4 1.5 2.9 3 0 0 3 3 3 0 Hepatic lectin, N-terminal domain KxDL PF10241.9 ORY08049.1 - 4.3 7.7 14.5 0.24 11.7 0.5 4.4 4 1 0 4 4 4 0 Uncharacterized conserved protein DivIC PF04977.15 ORY08049.1 - 6.8 6.5 17.3 1.9 8.3 0.7 4.7 5 0 0 5 5 5 0 Septum formation initiator DUF1593 PF07632.11 ORY08051.1 - 7e-88 294.4 0.0 9.3e-88 294.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1593) REJ PF02010.15 ORY08051.1 - 0.0024 16.7 0.0 0.0033 16.3 0.0 1.1 1 0 0 1 1 1 1 REJ domain CSTF1_dimer PF16699.5 ORY08051.1 - 0.066 13.0 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Cleavage stimulation factor subunit 1, dimerisation domain HlyD_3 PF13437.6 ORY08051.1 - 0.074 13.8 0.0 0.2 12.4 0.0 1.7 1 0 0 1 1 1 0 HlyD family secretion protein Pkinase PF00069.25 ORY08052.1 - 1.4e-14 54.1 0.0 2.5e-14 53.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY08052.1 - 2.1e-09 37.0 0.0 9.5e-09 34.9 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY08052.1 - 0.15 11.3 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 Kinase-like 3A PF00803.18 ORY08054.1 - 0.046 13.0 0.0 0.056 12.7 0.0 1.2 1 0 0 1 1 1 0 3A/RNA2 movement protein family Bestrophin PF01062.21 ORY08055.1 - 1.1e-33 117.0 0.0 1.5e-33 116.5 0.0 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Ribonuc_L-PSP PF01042.21 ORY08056.1 - 1.9e-39 134.4 0.0 2.2e-39 134.2 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Pribosyltran PF00156.27 ORY08057.1 - 1.5e-15 57.1 0.0 2.1e-15 56.6 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 ORY08057.1 - 0.018 14.5 0.0 0.025 14.0 0.0 1.2 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase AIRS_C PF02769.22 ORY08058.1 - 5.5e-32 111.1 0.1 2.7e-31 108.8 0.1 2.1 2 0 0 2 2 2 1 AIR synthase related protein, C-terminal domain AIRS PF00586.24 ORY08058.1 - 2.1e-13 50.7 1.3 2.1e-13 50.7 1.3 2.0 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain GHMP_kinases_N PF00288.26 ORY08058.1 - 9.9e-12 44.9 0.0 9.9e-12 44.9 0.0 2.6 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 ORY08058.1 - 0.0022 18.3 0.0 0.0067 16.8 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases C terminal HTH_23 PF13384.6 ORY08059.1 - 7.6e-06 25.6 0.2 1.9e-05 24.3 0.2 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 ORY08059.1 - 0.0012 19.0 0.2 0.0024 18.0 0.2 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_1_2 PF13022.6 ORY08059.1 - 0.01 16.0 0.0 0.023 14.8 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase AAA PF00004.29 ORY08061.1 - 7.7e-19 68.4 0.0 1.9e-18 67.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 ORY08061.1 - 1.6e-05 25.2 1.3 0.0036 17.6 0.0 2.8 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 ORY08061.1 - 0.00038 20.2 0.0 0.00076 19.3 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 ORY08061.1 - 0.0025 18.2 0.2 0.013 15.9 0.2 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 ORY08061.1 - 0.0054 16.7 0.0 0.018 15.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 ORY08061.1 - 0.0057 17.2 0.0 0.13 12.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 ORY08061.1 - 0.0066 16.4 0.0 0.052 13.5 0.0 2.4 3 0 0 3 3 3 1 Rad17 P-loop domain IstB_IS21 PF01695.17 ORY08061.1 - 0.0068 16.2 0.0 0.017 14.9 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_17 PF13207.6 ORY08061.1 - 0.0069 16.8 0.0 0.024 15.0 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 ORY08061.1 - 0.021 15.0 0.0 0.074 13.2 0.0 2.0 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 ORY08061.1 - 0.082 12.1 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_24 PF13479.6 ORY08061.1 - 0.093 12.4 0.1 0.45 10.2 0.0 2.3 2 1 0 2 2 2 0 AAA domain SASRP1 PF15160.6 ORY08064.1 - 0.074 12.7 0.0 0.079 12.6 0.0 1.1 1 0 0 1 1 1 0 Spermatogenesis-associated serine-rich protein 1 Abhydrolase_3 PF07859.13 ORY08065.1 - 6.5e-15 55.5 0.1 1.7e-14 54.2 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold COesterase PF00135.28 ORY08065.1 - 0.00071 18.6 0.0 0.0019 17.2 0.0 1.7 2 0 0 2 2 2 1 Carboxylesterase family Peptidase_S9 PF00326.21 ORY08065.1 - 0.0063 16.0 0.1 1.5 8.3 0.0 2.5 2 1 0 2 2 2 2 Prolyl oligopeptidase family Aldo_ket_red PF00248.21 ORY08067.1 - 9e-42 143.3 0.0 2.4e-39 135.3 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Myb_DNA-bind_6 PF13921.6 ORY08068.1 - 0.11 12.8 3.4 4.8 7.5 0.4 2.4 2 0 0 2 2 2 0 Myb-like DNA-binding domain ER_lumen_recept PF00810.18 ORY08071.1 - 3.2e-41 141.6 8.5 4.3e-41 141.2 8.5 1.2 1 0 0 1 1 1 1 ER lumen protein retaining receptor DUF4199 PF13858.6 ORY08071.1 - 0.016 15.6 3.0 0.028 14.8 3.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) FSA_C PF10479.9 ORY08074.1 - 0.54 8.3 8.3 0.68 8.0 8.3 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus FAP PF07174.11 ORY08074.1 - 2.8 7.3 14.8 4 6.8 14.8 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) PKcGMP_CC PF16808.5 ORY08075.1 - 4.5 7.2 13.8 0.42 10.5 0.3 3.7 4 0 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Transp_cyt_pur PF02133.15 ORY08076.1 - 7e-19 67.9 40.7 1.2e-18 67.1 40.7 1.4 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF5453 PF17534.2 ORY08076.1 - 0.014 15.3 0.7 0.014 15.3 0.7 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5453) Peptidase_M48_N PF16491.5 ORY08076.1 - 4.5 7.1 11.0 7.4 6.4 2.8 2.7 2 0 0 2 2 2 0 CAAX prenyl protease N-terminal, five membrane helices FAM221 PF14753.6 ORY08077.1 - 0.038 13.6 0.1 0.046 13.3 0.1 1.0 1 0 0 1 1 1 0 Protein FAM221A/B Amino_oxidase PF01593.24 ORY08078.1 - 3.5e-38 132.0 0.0 1.7e-36 126.5 0.0 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 ORY08078.1 - 1.5e-08 34.7 0.1 3.8e-08 33.4 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 ORY08078.1 - 0.02 14.2 1.7 0.033 13.5 0.5 1.9 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORY08078.1 - 0.026 15.1 0.4 1.8 9.2 0.3 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 ORY08078.1 - 0.029 13.7 0.1 0.069 12.5 0.2 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ORY08078.1 - 0.039 13.2 1.3 0.05 12.8 0.2 1.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 ORY08078.1 - 0.044 13.1 0.1 0.076 12.3 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 ORY08078.1 - 0.061 12.9 1.2 0.32 10.5 1.1 1.9 1 1 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 ORY08078.1 - 0.081 12.2 0.4 0.12 11.6 0.4 1.2 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.22 ORY08078.1 - 0.15 11.1 0.2 0.21 10.6 0.2 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A Thi4 PF01946.17 ORY08078.1 - 0.3 10.3 2.1 0.34 10.1 0.2 1.8 2 0 0 2 2 2 0 Thi4 family HI0933_like PF03486.14 ORY08078.1 - 0.55 8.9 1.6 0.85 8.2 0.2 1.8 2 0 0 2 2 2 0 HI0933-like protein A_deaminase PF00962.22 ORY08180.1 - 1.6e-70 238.1 0.0 1.9e-70 237.8 0.0 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase TauD PF02668.16 ORY08181.1 - 1.2e-45 156.5 3.8 1.6e-45 156.0 3.8 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 ORY08181.1 - 4.6e-05 24.0 0.2 0.00013 22.5 0.2 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF971) Mito_carr PF00153.27 ORY08182.1 - 5.7e-61 202.5 0.9 1.3e-19 69.9 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 ORY08182.1 - 0.045 12.9 0.1 0.43 9.7 0.0 2.6 3 0 0 3 3 3 0 Gammaproteobacterial serine protease Ofd1_CTDD PF10637.9 ORY08183.1 - 3.9e-89 298.4 0.0 8.4e-87 290.7 0.0 2.2 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 ORY08183.1 - 2.3e-21 76.3 0.0 4.6e-21 75.3 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 ORY08183.1 - 4.5e-11 43.5 0.0 9.6e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PMT PF02366.18 ORY08184.1 - 8e-85 284.3 18.1 1.3e-84 283.7 18.1 1.3 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 ORY08184.1 - 4.1e-70 235.4 1.2 4.1e-70 235.4 1.2 3.0 2 1 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 ORY08184.1 - 1.1e-20 74.3 1.7 1.7e-20 73.6 1.7 1.3 1 0 0 1 1 1 1 MIR domain COesterase PF00135.28 ORY08185.1 - 3.4e-47 161.5 0.0 1.1e-46 159.8 0.0 1.7 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 ORY08185.1 - 3.8e-06 26.9 0.0 0.0018 18.2 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 ORY08185.1 - 0.063 12.1 0.6 0.55 9.0 0.6 1.9 1 1 0 1 1 1 0 Steryl acetyl hydrolase Glyco_hydro_18 PF00704.28 ORY08186.1 - 1.2e-59 202.6 0.4 1.4e-59 202.4 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 MFS_1 PF07690.16 ORY08188.1 - 1.1e-48 166.0 27.9 1.1e-48 166.0 27.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY08188.1 - 2.3e-07 30.0 8.8 2.3e-07 30.0 8.8 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter adh_short PF00106.25 ORY08189.1 - 8.7e-13 48.2 0.2 1.5e-08 34.4 0.0 2.7 2 1 1 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.6 ORY08189.1 - 7.3e-09 35.5 0.0 1.2e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY08189.1 - 0.019 14.9 0.1 1.1 9.2 0.0 2.2 1 1 1 2 2 2 0 KR domain HET PF06985.11 ORY08191.1 - 0.00023 21.5 1.7 0.16 12.3 0.2 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) AAA PF00004.29 ORY08193.1 - 1.7e-51 174.1 0.0 4e-43 147.0 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 ORY08193.1 - 7.9e-06 25.6 2.6 0.0096 15.7 0.1 2.7 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 ORY08193.1 - 6.6e-05 23.4 3.0 0.023 15.1 0.0 4.0 3 1 1 4 4 3 1 AAA ATPase domain RuvB_N PF05496.12 ORY08193.1 - 0.00013 21.8 0.0 0.00047 19.9 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Parvo_NS1 PF01057.17 ORY08193.1 - 0.00057 19.1 0.0 0.001 18.2 0.0 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_18 PF13238.6 ORY08193.1 - 0.0012 19.4 0.2 0.095 13.2 0.0 2.8 3 0 0 3 3 2 1 AAA domain RNA_helicase PF00910.22 ORY08193.1 - 0.0018 18.6 0.0 0.017 15.5 0.0 2.4 2 0 0 2 2 2 1 RNA helicase AAA_25 PF13481.6 ORY08193.1 - 0.0033 17.0 0.1 0.088 12.4 0.0 3.0 2 1 0 2 2 2 1 AAA domain TIP49 PF06068.13 ORY08193.1 - 0.0039 16.5 0.1 0.012 14.8 0.0 1.7 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_2 PF07724.14 ORY08193.1 - 0.004 17.3 0.0 0.0097 16.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 ORY08193.1 - 0.0056 16.9 0.1 0.046 14.0 0.0 2.6 2 1 0 2 2 1 1 AAA domain IstB_IS21 PF01695.17 ORY08193.1 - 0.0082 15.9 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_5 PF07728.14 ORY08193.1 - 0.0088 16.1 0.1 0.13 12.3 0.0 3.1 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 ORY08193.1 - 0.028 13.8 0.1 0.055 12.8 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ATPase PF06745.13 ORY08193.1 - 0.031 13.6 0.0 0.087 12.2 0.0 1.7 2 0 0 2 2 1 0 KaiC Vps4_C PF09336.10 ORY08193.1 - 0.032 14.2 0.4 0.63 10.1 0.1 3.1 4 0 0 4 4 3 0 Vps4 C terminal oligomerisation domain AAA_7 PF12775.7 ORY08193.1 - 0.041 13.4 0.0 0.084 12.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region TsaE PF02367.17 ORY08193.1 - 0.063 13.3 0.0 0.17 11.9 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 ORY08193.1 - 0.068 13.3 0.0 0.41 10.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 ORY08193.1 - 0.095 12.1 0.0 0.21 11.0 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein SKI PF01202.22 ORY08193.1 - 0.098 12.8 0.2 9.5 6.3 0.0 2.8 2 0 0 2 2 2 0 Shikimate kinase AAA_17 PF13207.6 ORY08193.1 - 0.12 12.8 0.0 2.5 8.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 ORY08193.1 - 0.13 12.5 0.0 0.31 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 ORY08193.1 - 0.2 11.3 0.7 0.96 9.1 0.1 2.1 2 0 0 2 2 2 0 AAA domain Abhydro_lipase PF04083.16 ORY08194.1 - 2.7e-18 65.3 0.0 5.9e-18 64.2 0.0 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 ORY08194.1 - 9.7e-08 32.0 0.1 4e-07 30.0 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ORY08194.1 - 0.00063 19.1 0.0 0.0012 18.2 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF900 PF05990.12 ORY08194.1 - 0.065 12.7 0.0 0.27 10.7 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) DUF3453 PF11935.8 ORY08196.1 - 5.2e-65 219.3 0.0 8.4e-65 218.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3453) Coiled-coil_56 PF09813.9 ORY08197.1 - 2.3e-05 24.4 0.0 2.6e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 56 TPP_enzyme_N PF02776.18 ORY08198.1 - 6.8e-45 152.7 0.0 1.7e-44 151.4 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 ORY08198.1 - 5.6e-34 116.8 0.1 1.3e-33 115.6 0.0 1.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 ORY08198.1 - 4.4e-20 72.0 0.1 7.7e-20 71.2 0.1 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain B12-binding PF02310.19 ORY08198.1 - 0.0078 16.3 0.1 0.025 14.6 0.1 1.9 1 0 0 1 1 1 1 B12 binding domain NMT1_3 PF16868.5 ORY08198.1 - 0.12 11.8 0.6 0.29 10.5 0.0 1.8 2 0 0 2 2 2 0 NMT1-like family SH3_9 PF14604.6 ORY08199.1 - 2.4e-10 40.1 0.0 4.6e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 ORY08199.1 - 3.9e-07 29.6 0.0 7.4e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 ORY08199.1 - 9.6e-05 22.0 0.0 0.00019 21.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain DUF2845 PF11006.8 ORY08199.1 - 0.043 13.9 0.4 0.12 12.5 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2845) DZR PF12773.7 ORY08199.1 - 0.088 12.8 3.0 0.45 10.6 0.2 2.5 2 0 0 2 2 2 0 Double zinc ribbon zf-Di19 PF05605.12 ORY08199.1 - 0.19 12.0 5.7 6.9 7.0 0.5 3.1 2 1 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-ribbon_3 PF13248.6 ORY08199.1 - 0.67 9.4 4.8 15 5.2 1.9 2.7 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_2 PF13240.6 ORY08199.1 - 1.7 8.5 7.9 2.1 8.2 2.4 2.8 2 0 0 2 2 2 0 zinc-ribbon domain CEP209_CC5 PF16574.5 ORY08199.1 - 2.2 8.5 6.3 1.1 9.4 0.2 3.0 3 0 0 3 3 3 0 Coiled-coil region of centrosome protein CE290 tRNA_bind_2 PF13725.6 ORY08200.1 - 0.0097 15.6 1.3 0.022 14.5 0.1 2.1 3 0 0 3 3 3 1 Possible tRNA binding domain Med16 PF11635.8 ORY08200.1 - 0.054 11.4 0.2 0.075 10.9 0.2 1.2 1 0 0 1 1 1 0 Mediator complex subunit 16 DUF4132 PF13569.6 ORY08200.1 - 0.079 12.8 0.2 0.15 11.8 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4132) Sec20 PF03908.13 ORY08201.1 - 2.1e-16 59.6 0.2 2.1e-16 59.6 0.2 2.9 3 0 0 3 3 3 1 Sec20 FapA PF03961.13 ORY08201.1 - 0.53 8.8 7.8 0.17 10.5 3.6 2.1 2 1 0 2 2 2 0 Flagellar Assembly Protein A DUF1664 PF07889.12 ORY08201.1 - 1.1 9.3 3.5 1.9 8.5 0.9 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) MRP_L53 PF10780.9 ORY08202.1 - 2.7e-21 75.5 0.6 3.9e-21 75.0 0.2 1.4 2 0 0 2 2 2 1 39S ribosomal protein L53/MRP-L53 Pyrophosphatase PF00719.19 ORY08203.1 - 2.8e-58 196.2 0.1 3.7e-58 195.9 0.1 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase RRM_1 PF00076.22 ORY08206.1 - 1.5e-21 76.0 0.0 1.8e-21 75.7 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 ORY08206.1 - 0.00056 20.0 0.0 0.00088 19.3 0.0 1.4 1 1 0 1 1 1 1 RNA recognition motif PAP_PilO PF06864.12 ORY08206.1 - 0.024 13.5 0.1 0.028 13.2 0.1 1.0 1 0 0 1 1 1 0 Pilin accessory protein (PilO) Abhydrolase_4 PF08386.10 ORY08207.1 - 1.6e-20 73.2 0.0 3.7e-20 72.0 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.20 ORY08207.1 - 9.6e-19 68.0 0.0 1.3e-16 61.0 0.0 3.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold WD40 PF00400.32 ORY08208.1 - 1e-05 26.1 5.3 0.00024 21.8 0.3 4.8 5 0 0 5 5 5 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY08208.1 - 0.0032 17.7 0.0 9.4 6.6 0.0 4.0 1 1 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain DUF2415 PF10313.9 ORY08208.1 - 0.053 13.4 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein domain (DUF2415) Chitin_synth_2 PF03142.15 ORY08210.1 - 2.7e-290 963.5 1.0 5.8e-290 962.4 0.2 1.7 2 0 0 2 2 2 1 Chitin synthase Glyco_trans_2_3 PF13632.6 ORY08210.1 - 1.1e-12 48.3 6.3 4.6e-12 46.3 6.3 2.1 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 ORY08210.1 - 9.9e-10 38.7 0.0 1.2e-08 35.1 0.0 2.2 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 ORY08210.1 - 0.0004 19.9 0.0 0.0052 16.3 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 ORY08210.1 - 0.18 11.6 0.0 1.5 8.6 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferase family 2 Sel1 PF08238.12 ORY08211.1 - 2.1e-40 136.2 28.0 2.4e-06 28.0 0.5 7.4 7 0 0 7 7 7 7 Sel1 repeat TPR_6 PF13174.6 ORY08211.1 - 0.035 14.7 6.6 1.2 10.0 0.1 4.2 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 ORY08211.1 - 3.1 8.5 16.0 11 6.8 1.5 4.3 3 1 1 4 4 4 0 Tetratricopeptide repeat Aminotran_1_2 PF00155.21 ORY08212.1 - 5.2e-17 62.1 0.0 6.7e-17 61.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 ORY08212.1 - 0.00016 20.6 0.0 0.00043 19.2 0.0 1.7 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase DAD PF02109.16 ORY08213.1 - 3.8e-51 172.0 1.8 4.7e-51 171.7 1.8 1.1 1 0 0 1 1 1 1 DAD family HTH_OrfB_IS605 PF12323.8 ORY08213.1 - 0.075 12.5 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain E1-E2_ATPase PF00122.20 ORY08213.1 - 0.11 12.1 0.1 0.14 11.7 0.1 1.2 1 0 0 1 1 1 0 E1-E2 ATPase Tmemb_14 PF03647.13 ORY08214.1 - 5.9e-23 81.4 9.1 7.2e-23 81.1 9.1 1.1 1 0 0 1 1 1 1 Transmembrane proteins 14C RabGAP-TBC PF00566.18 ORY08216.1 - 1.5e-35 122.8 0.0 4.4e-29 101.7 0.0 2.1 2 0 0 2 2 2 2 Rab-GTPase-TBC domain Sulfate_transp PF00916.20 ORY08217.1 - 8.7e-106 353.9 21.7 1.2e-105 353.4 21.7 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 ORY08217.1 - 3.8e-08 33.0 0.0 6.9e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 ORY08217.1 - 0.0016 18.8 2.5 0.0016 18.8 2.5 3.4 3 1 0 4 4 4 1 Molybdate transporter of MFS superfamily SNN_transmemb PF09049.10 ORY08217.1 - 0.32 11.0 6.9 0.15 12.1 0.4 3.7 3 0 0 3 3 3 0 Stannin transmembrane COPIIcoated_ERV PF07970.12 ORY08218.1 - 6.1e-86 287.8 0.0 1e-85 287.1 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 ORY08218.1 - 2.9e-30 104.5 0.0 2.3e-29 101.6 0.0 2.1 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) DUF829 PF05705.14 ORY08219.1 - 1.8e-46 159.0 0.0 2.2e-46 158.7 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Lipase_GDSL_2 PF13472.6 ORY08219.1 - 0.13 12.6 0.0 0.2 12.0 0.0 1.2 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family LIM PF00412.22 ORY08220.1 - 2.2e-12 47.0 27.5 4.6e-10 39.6 2.1 3.1 3 0 0 3 3 3 2 LIM domain Helo_like_N PF17111.5 ORY08220.1 - 3.9e-07 29.7 1.8 6.6e-07 28.9 1.8 1.4 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins NPV_P10 PF05531.12 ORY08220.1 - 0.091 13.2 0.2 0.31 11.5 0.2 1.9 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein bZIP_1 PF00170.21 ORY08220.1 - 5.4 7.2 9.7 0.18 11.9 1.0 2.4 2 0 0 2 2 2 0 bZIP transcription factor Zn-ribbon_8 PF09723.10 ORY08220.1 - 8.4 6.6 28.3 0.49 10.6 1.0 5.7 5 1 1 6 6 6 0 Zinc ribbon domain Glyco_hydro_16 PF00722.21 ORY08221.1 - 2.8e-08 33.5 0.0 9.2e-08 31.8 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 Thiolase_N PF00108.23 ORY08222.1 - 5.1e-92 307.9 1.0 6.6e-92 307.5 0.3 1.5 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 ORY08222.1 - 1.3e-44 150.8 3.0 2.4e-43 146.7 1.8 2.3 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 ORY08222.1 - 4.4e-06 26.5 2.4 0.00058 19.5 1.0 2.7 2 1 1 3 3 3 2 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 ORY08222.1 - 0.00099 18.9 2.6 0.033 14.0 0.1 3.0 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III SpoVAD PF07451.11 ORY08222.1 - 0.019 13.7 0.2 0.037 12.7 0.2 1.4 1 0 0 1 1 1 0 Stage V sporulation protein AD (SpoVAD) GTP_EFTU PF00009.27 ORY08223.1 - 4.9e-45 153.5 0.0 6.8e-45 153.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFTUD2 PF16004.5 ORY08223.1 - 7.6e-38 129.8 3.2 1.4e-37 129.0 3.2 1.5 1 0 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EFG_IV PF03764.18 ORY08223.1 - 4.3e-22 78.1 0.0 1.6e-21 76.3 0.0 2.1 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 ORY08223.1 - 6.6e-19 67.7 0.0 2.1e-18 66.2 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 ORY08223.1 - 1.2e-07 31.9 0.1 4.6e-07 30.1 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_II PF14492.6 ORY08223.1 - 1.3e-06 28.4 0.0 3.1e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 ORY08223.1 - 0.00017 21.7 0.1 0.00032 20.8 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF5505 PF17610.2 ORY08223.1 - 0.15 12.1 0.1 0.29 11.1 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5505) Dyp_perox PF04261.12 ORY08224.1 - 2.1e-87 293.2 0.0 2.4e-87 293.0 0.0 1.0 1 0 0 1 1 1 1 Dyp-type peroxidase family CDP-OH_P_transf PF01066.21 ORY08226.1 - 1.4e-15 57.8 0.1 1.4e-15 57.8 0.1 2.7 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase NACHT PF05729.12 ORY08227.1 - 4.1e-09 36.6 0.0 8.3e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 ORY08227.1 - 1.1e-05 25.9 0.1 0.00016 22.1 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain DUF676 PF05057.14 ORY08227.1 - 2.2e-05 24.1 0.0 5.5e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 ORY08227.1 - 0.00021 22.0 0.0 0.00036 21.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2075 PF09848.9 ORY08227.1 - 0.0022 17.3 1.9 0.046 13.0 0.0 2.6 2 1 1 3 3 3 1 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.22 ORY08227.1 - 0.004 17.5 0.0 0.013 15.9 0.0 1.9 1 0 0 1 1 1 1 RNA helicase DUF829 PF05705.14 ORY08227.1 - 0.0054 16.7 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) AAA_22 PF13401.6 ORY08227.1 - 0.011 16.1 0.0 0.22 11.8 0.0 2.8 3 0 0 3 3 3 0 AAA domain PGAP1 PF07819.13 ORY08227.1 - 0.014 15.1 0.0 0.027 14.2 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Rad17 PF03215.15 ORY08227.1 - 0.029 14.3 0.0 0.28 11.1 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain Hydrolase_4 PF12146.8 ORY08227.1 - 0.03 13.6 0.0 0.12 11.7 0.0 2.0 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_9 PF10081.9 ORY08227.1 - 0.031 13.3 0.0 0.055 12.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta-hydrolase family AAA_18 PF13238.6 ORY08227.1 - 0.035 14.7 0.0 0.22 12.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain MFS_1 PF07690.16 ORY08325.1 - 1.9e-42 145.5 38.1 1.9e-42 145.5 38.1 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 ORY08325.1 - 7.8e-06 24.4 10.3 0.00027 19.4 0.9 3.3 2 1 0 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family TPMT PF05724.11 ORY08326.1 - 2e-28 99.6 0.0 3.1e-28 98.9 0.0 1.3 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_23 PF13489.6 ORY08326.1 - 8.6e-07 28.9 0.0 1.2e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY08326.1 - 8.6e-05 22.4 0.0 0.049 13.4 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 ORY08326.1 - 0.00053 20.6 0.0 0.0012 19.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY08326.1 - 0.0021 18.8 0.0 0.0062 17.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY08326.1 - 0.0052 17.5 0.0 0.032 14.9 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain N2227 PF07942.12 ORY08326.1 - 0.045 13.0 0.0 0.062 12.5 0.0 1.1 1 0 0 1 1 1 0 N2227-like protein AdoMet_MTase PF07757.13 ORY08326.1 - 0.077 13.3 0.0 0.15 12.4 0.0 1.4 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase DOT1 PF08123.13 ORY08326.1 - 0.2 11.2 0.0 0.27 10.7 0.0 1.1 1 0 0 1 1 1 0 Histone methylation protein DOT1 OTU PF02338.19 ORY08327.1 - 5.7e-20 72.1 0.1 1.1e-18 67.9 0.0 2.4 2 0 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 ORY08327.1 - 5.3e-05 22.8 0.0 0.016 14.7 0.0 2.4 2 0 0 2 2 2 2 Peptidase C65 Otubain PsbU PF06514.11 ORY08327.1 - 0.17 11.9 0.0 0.4 10.7 0.0 1.6 1 0 0 1 1 1 0 Photosystem II 12 kDa extrinsic protein (PsbU) SMC_Nse1 PF07574.13 ORY08328.1 - 0.087 12.7 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Nse1 non-SMC component of SMC5-6 complex An_peroxidase PF03098.15 ORY08329.1 - 1.1e-119 400.5 0.0 1.3e-119 400.2 0.0 1.0 1 0 0 1 1 1 1 Animal haem peroxidase DUF4714 PF15833.5 ORY08330.1 - 0.086 12.8 0.5 0.16 12.0 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4714) RasGAP PF00616.19 ORY08332.1 - 2.5e-34 118.8 0.1 1.4e-23 83.7 0.0 2.8 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase PH PF00169.29 ORY08332.1 - 6e-05 23.5 0.0 0.064 13.8 0.0 2.7 2 0 0 2 2 2 2 PH domain C2 PF00168.30 ORY08332.1 - 0.0023 18.2 0.0 0.012 15.9 0.0 2.1 2 0 0 2 2 2 1 C2 domain PH_11 PF15413.6 ORY08332.1 - 0.18 12.3 0.0 0.52 10.8 0.0 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain Pro_isomerase PF00160.21 ORY08333.1 - 7.1e-47 159.6 0.2 1e-46 159.1 0.2 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_2 PF07719.17 ORY08333.1 - 2.1e-06 27.4 6.9 0.015 15.3 0.3 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 ORY08333.1 - 9.1e-05 22.1 8.0 0.45 10.4 0.1 3.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 ORY08333.1 - 0.0039 17.5 2.9 0.18 12.1 0.9 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 ORY08333.1 - 0.0069 17.0 3.7 0.5 11.1 2.6 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat RIP PF00161.19 ORY08333.1 - 0.14 11.7 0.2 1.2 8.7 0.1 2.0 1 1 0 2 2 2 0 Ribosome inactivating protein TPR_6 PF13174.6 ORY08333.1 - 0.24 12.1 2.2 20 6.1 0.2 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat IFRD PF05004.13 ORY08334.1 - 2e-81 273.5 7.8 2.5e-81 273.2 7.8 1.1 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) Adaptin_N PF01602.20 ORY08334.1 - 0.016 13.8 0.1 0.091 11.3 0.1 2.0 2 0 0 2 2 2 0 Adaptin N terminal region zf-C2H2 PF00096.26 ORY08335.1 - 4e-05 23.8 6.1 0.081 13.4 1.8 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type FOXP-CC PF16159.5 ORY08335.1 - 0.045 14.4 0.7 7.6 7.2 0.1 2.4 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 ORY08335.1 - 0.085 13.7 3.3 5.3 8.2 0.1 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger Not3 PF04065.15 ORY08336.1 - 2.7e-91 305.1 29.3 2.7e-91 305.1 29.3 1.8 2 0 0 2 2 2 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 ORY08336.1 - 3.5e-43 146.8 12.1 8.7e-43 145.5 12.1 1.7 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family DUF2373 PF10180.9 ORY08336.1 - 0.0039 17.0 2.4 0.01 15.6 2.4 1.7 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) DUF641 PF04859.12 ORY08336.1 - 0.034 14.5 13.2 0.97 9.8 13.2 2.6 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) Serine_rich PF08824.10 ORY08336.1 - 0.28 11.2 4.0 3.1 7.8 0.4 2.6 1 1 1 2 2 2 0 Serine rich protein interaction domain FlaC_arch PF05377.11 ORY08336.1 - 0.87 10.0 9.7 21 5.6 0.7 4.3 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) LPP PF04728.13 ORY08336.1 - 1.5 9.3 5.0 1.8 9.0 0.0 3.5 4 0 0 4 4 4 0 Lipoprotein leucine-zipper CorA PF01544.18 ORY08336.1 - 1.7 7.9 6.6 0.57 9.4 3.0 1.9 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein Osmo_CC PF08946.10 ORY08336.1 - 6.6 7.1 8.5 0.71 10.2 0.1 3.1 3 0 0 3 3 3 0 Osmosensory transporter coiled coil Tyr_Deacylase PF02580.16 ORY08337.1 - 6.4e-52 175.9 0.0 7.8e-52 175.6 0.0 1.1 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase DUF1365 PF07103.11 ORY08338.1 - 3.6e-56 190.5 0.0 5.1e-56 190.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1365) ICL PF00463.21 ORY08340.1 - 2.4e-299 993.2 2.2 2.7e-299 993.0 2.2 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 ORY08340.1 - 1.8e-11 44.0 0.1 2e-10 40.5 0.0 2.2 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase Pribosyl_synth PF14572.6 ORY08343.1 - 2.2e-38 132.1 3.2 2.2e-33 115.8 1.8 2.2 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 ORY08343.1 - 3.5e-35 120.5 0.0 8.4e-35 119.2 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 ORY08343.1 - 2.6e-14 53.0 0.9 8.3e-14 51.4 0.5 1.9 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 ORY08343.1 - 0.0024 17.4 0.1 0.0037 16.7 0.1 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase VIT PF08487.10 ORY08344.1 - 3.3e-39 133.5 0.1 1.4e-38 131.5 0.1 2.2 2 0 0 2 2 2 1 Vault protein inter-alpha-trypsin domain VWA_3 PF13768.6 ORY08344.1 - 4e-29 101.6 0.0 6.9e-29 100.8 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT_2 PF13757.6 ORY08344.1 - 2.7e-16 59.2 0.0 6.4e-16 58.0 0.0 1.6 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA PF00092.28 ORY08344.1 - 1.2e-12 48.4 0.0 2.3e-12 47.5 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 ORY08344.1 - 1.9e-09 38.1 0.0 4.4e-09 36.9 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 ORY08344.1 - 0.0093 15.4 0.0 0.021 14.2 0.0 1.5 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein Synaptobrevin PF00957.21 ORY08344.1 - 0.021 14.6 0.3 0.044 13.6 0.3 1.5 1 0 0 1 1 1 0 Synaptobrevin vWA-TerF-like PF10138.9 ORY08344.1 - 0.15 12.2 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 vWA found in TerF C terminus TFIIA PF03153.13 ORY08344.1 - 8.4 6.3 13.2 0.57 10.1 8.2 1.5 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit PseudoU_synth_1 PF01416.20 ORY08345.1 - 2e-29 102.2 0.0 5.8e-28 97.5 0.0 2.5 2 0 0 2 2 2 1 tRNA pseudouridine synthase ubiquitin PF00240.23 ORY08346.1 - 0.00013 21.6 0.0 0.00013 21.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family YukD PF08817.10 ORY08346.1 - 0.0013 19.4 0.0 0.0014 19.3 0.0 1.3 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukD PIG-H PF10181.9 ORY08347.1 - 3.4e-25 87.7 0.5 3.4e-25 87.7 0.5 1.8 2 0 0 2 2 2 1 GPI-GlcNAc transferase complex, PIG-H component DIM1 PF02966.16 ORY08348.1 - 1.6e-69 231.8 0.2 1.8e-69 231.6 0.2 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 ORY08348.1 - 0.062 13.3 0.1 0.08 12.9 0.1 1.1 1 0 0 1 1 1 0 Thioredoxin vATP-synt_AC39 PF01992.16 ORY08349.1 - 1.4e-93 314.1 0.0 1.6e-93 313.9 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit UL16 PF17622.2 ORY08349.1 - 0.17 11.6 0.0 0.34 10.5 0.0 1.4 1 0 0 1 1 1 0 Viral unique long protein 16 Dynamin_N PF00350.23 ORY08350.1 - 7.5e-29 100.9 0.0 1.6e-28 99.8 0.0 1.6 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 ORY08350.1 - 4.2e-18 65.6 0.0 6.7e-18 64.9 0.0 1.3 1 0 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.23 ORY08350.1 - 1.8e-05 24.8 0.0 5.2e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 ORY08350.1 - 0.17 11.4 0.0 12 5.4 0.0 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B Peptidase_S49_N PF08496.10 ORY08350.1 - 0.4 10.7 0.0 0.4 10.7 0.0 2.1 3 0 0 3 3 3 0 Peptidase family S49 N-terminal Alpha-amylase PF00128.24 ORY08353.1 - 4.4e-57 194.2 0.0 6e-57 193.7 0.0 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.11 ORY08353.1 - 1.1e-15 57.6 0.2 3e-15 56.3 0.2 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) PLDc PF00614.22 ORY08356.1 - 1.6e-15 56.6 0.4 2.1e-06 27.7 0.2 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 ORY08356.1 - 3.4e-13 49.6 0.0 3.1e-07 30.3 0.0 3.2 2 1 0 2 2 2 2 PLD-like domain PX PF00787.24 ORY08356.1 - 3.8e-12 46.2 0.0 5.9e-11 42.3 0.0 2.7 3 0 0 3 3 3 1 PX domain Sugar_tr PF00083.24 ORY08357.1 - 1.7e-89 300.8 27.5 2.1e-89 300.5 27.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY08357.1 - 2e-20 73.0 43.1 3.4e-19 69.0 34.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 ORY08357.1 - 0.00034 19.2 3.9 0.00053 18.5 3.9 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Fungal_trans_2 PF11951.8 ORY08359.1 - 4e-06 25.9 0.0 0.04 12.7 0.0 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain cNMP_binding PF00027.29 ORY08360.1 - 2.1e-41 139.9 0.0 2.3e-20 72.4 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.17 ORY08360.1 - 9.7e-12 44.4 0.2 2e-11 43.3 0.2 1.6 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit AMPK1_CBM PF16561.5 ORY08361.1 - 1.6e-22 79.5 0.6 3e-22 78.6 0.6 1.3 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase CBM_48 PF02922.18 ORY08361.1 - 1.6e-05 25.2 0.1 0.00043 20.6 0.1 2.3 2 0 0 2 2 2 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) CBM53 PF16760.5 ORY08361.1 - 0.01 16.4 0.5 0.022 15.3 0.5 1.5 1 0 0 1 1 1 0 Starch/carbohydrate-binding module (family 53) Prenylcys_lyase PF07156.14 ORY08362.1 - 0.15 11.2 0.0 0.2 10.7 0.0 1.1 1 0 0 1 1 1 0 Prenylcysteine lyase Ank_2 PF12796.7 ORY08363.1 - 1.5e-05 25.5 0.1 0.00012 22.6 0.0 2.3 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY08363.1 - 0.12 13.0 0.3 0.46 11.1 0.0 2.3 2 1 0 2 2 2 0 Ankyrin repeats (many copies) DUF443 PF04276.12 ORY08363.1 - 0.2 11.4 0.0 0.46 10.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF443) PilJ PF13675.6 ORY08363.1 - 0.62 10.1 8.2 2 8.5 0.1 4.3 4 1 1 5 5 5 0 Type IV pili methyl-accepting chemotaxis transducer N-term BNR_2 PF13088.6 ORY08364.1 - 6.2e-21 74.9 2.7 3.4e-12 46.3 0.1 2.4 1 1 1 2 2 2 2 BNR repeat-like domain BNR PF02012.20 ORY08364.1 - 4.1e-10 38.1 19.7 0.19 11.8 0.7 5.9 5 0 0 5 5 5 5 BNR/Asp-box repeat BNR_4 PF15892.5 ORY08364.1 - 3.3e-07 30.0 0.1 0.00021 20.7 0.0 2.5 1 1 1 2 2 2 2 BNR repeat-containing family member Sortilin-Vps10 PF15902.5 ORY08364.1 - 6.3e-07 28.5 0.7 0.00018 20.4 0.1 2.5 2 2 0 2 2 2 2 Sortilin, neurotensin receptor 3, BNR_3 PF13859.6 ORY08364.1 - 0.0013 18.1 1.0 0.2 10.9 0.0 3.0 1 1 1 3 3 3 1 BNR repeat-like domain PSII_BNR PF14870.6 ORY08364.1 - 0.0073 15.6 3.6 0.93 8.7 0.1 4.0 3 2 1 5 5 5 1 Photosynthesis system II assembly factor YCF48 DUF4185 PF13810.6 ORY08364.1 - 0.018 14.3 13.8 1.3 8.2 0.1 4.7 1 1 1 4 4 4 0 Domain of unknown function (DUF4185) CyRPA PF18638.1 ORY08364.1 - 0.023 13.9 0.6 23 4.0 0.0 3.9 4 0 0 4 4 4 0 Cysteine-Rich Protective Antigen 6 bladed domain End_beta_propel PF12217.8 ORY08364.1 - 0.063 11.9 5.7 0.57 8.8 0.1 3.5 3 2 2 5 5 5 0 Catalytic beta propeller domain of bacteriophage endosialidase HeH PF12949.7 ORY08366.1 - 0.0054 16.4 0.2 0.02 14.6 0.0 2.1 2 0 0 2 2 2 1 HeH/LEM domain Rho_N PF07498.12 ORY08366.1 - 0.037 14.0 0.0 0.1 12.6 0.0 1.7 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain GTP_EFTU PF00009.27 ORY08367.1 - 7e-50 169.3 0.0 1.1e-49 168.6 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 ORY08367.1 - 2.3e-43 146.7 1.4 4e-43 145.9 1.4 1.4 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 ORY08367.1 - 3.1e-19 68.8 0.0 6.6e-19 67.7 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 ORY08367.1 - 2.4e-07 31.0 0.2 4.9e-07 30.1 0.2 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 ORY08367.1 - 2e-05 24.7 0.0 6.2e-05 23.1 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase Ras PF00071.22 ORY08367.1 - 0.00049 19.7 0.0 0.0013 18.3 0.0 1.7 2 0 0 2 2 2 1 Ras family EFG_II PF14492.6 ORY08367.1 - 0.0024 17.9 0.0 0.0065 16.5 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II SRPRB PF09439.10 ORY08367.1 - 0.0055 16.2 0.0 0.013 15.0 0.0 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit RF3_C PF16658.5 ORY08367.1 - 0.046 13.5 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain MMR_HSR1_Xtn PF16897.5 ORY08367.1 - 0.11 12.5 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Snurportin1 PF11538.8 ORY08367.1 - 0.32 11.2 3.4 0.7 10.1 3.4 1.5 1 0 0 1 1 1 0 Snurportin1 HORMA PF02301.18 ORY08368.1 - 8.9e-32 110.4 0.1 1.1e-31 110.1 0.1 1.1 1 0 0 1 1 1 1 HORMA domain ATG101 PF07855.12 ORY08368.1 - 0.00049 20.1 0.6 0.0017 18.4 0.6 1.9 1 1 0 1 1 1 1 Autophagy-related protein 101 DUF4760 PF15956.5 ORY08368.1 - 0.057 13.5 0.7 0.19 11.8 0.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4760) DUF2660 PF10859.8 ORY08368.1 - 0.087 13.3 0.3 0.4 11.2 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2660) Glyco_trans_2_3 PF13632.6 ORY08369.1 - 7.9e-50 169.5 0.8 2e-49 168.2 0.8 1.8 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 ORY08369.1 - 4.4e-08 33.1 0.1 1.1e-05 25.4 0.0 2.8 3 0 0 3 3 3 2 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 ORY08369.1 - 0.00033 20.6 0.0 0.0006 19.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 ORY08369.1 - 0.00054 19.5 0.0 0.0021 17.5 0.0 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 21 bZIP_1 PF00170.21 ORY08370.1 - 1.5e-07 31.4 12.8 2.5e-07 30.7 12.8 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 ORY08370.1 - 3.5e-06 27.0 10.5 9.1e-06 25.7 10.5 1.7 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 ORY08370.1 - 0.0031 18.0 8.3 0.0062 17.0 8.3 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor Phlebovirus_NSM PF07246.11 ORY08370.1 - 0.19 11.1 0.7 0.28 10.5 0.7 1.1 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M DMPK_coil PF08826.10 ORY08370.1 - 0.32 11.1 6.0 0.54 10.4 6.0 1.4 1 1 0 1 1 1 0 DMPK coiled coil domain like Response_reg PF00072.24 ORY08371.1 - 8.6e-21 74.2 0.1 2.5e-20 72.7 0.1 1.7 1 1 0 1 1 1 1 Response regulator receiver domain Nitroreductase PF00881.24 ORY08371.1 - 0.029 14.4 0.0 0.037 14.1 0.0 1.3 1 0 0 1 1 1 0 Nitroreductase family Aldedh PF00171.22 ORY08374.1 - 1.3e-94 317.4 6.1 2e-61 207.9 2.7 2.0 2 0 0 2 2 2 2 Aldehyde dehydrogenase family SNF2_N PF00176.23 ORY08446.1 - 7.3e-65 219.0 0.1 7e-64 215.7 0.1 2.4 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ORY08446.1 - 1.2e-17 64.2 0.1 5e-17 62.2 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY08446.1 - 1.3e-05 25.2 0.0 1.3e-05 25.2 0.0 2.6 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DUF1840 PF08895.11 ORY08446.1 - 0.87 9.9 13.3 0.56 10.6 3.8 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF1840) DUF4267 PF14087.6 ORY08447.1 - 4.6e-05 23.4 3.6 6.3e-05 23.0 3.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) DUF3425 PF11905.8 ORY08448.1 - 1.9e-11 44.0 6.1 4.8e-10 39.5 6.1 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) PHC2_SAM_assoc PF16616.5 ORY08448.1 - 0.044 14.6 2.3 0.044 14.6 2.3 2.9 4 0 0 4 4 4 0 Unstructured region on Polyhomeotic-like protein 1 and 2 RabGAP-TBC PF00566.18 ORY08450.1 - 2.3e-50 171.2 0.0 4e-50 170.4 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain ZapB PF06005.12 ORY08450.1 - 0.012 16.1 3.3 0.012 16.1 3.3 4.4 5 0 0 5 5 5 0 Cell division protein ZapB LMBR1 PF04791.16 ORY08450.1 - 0.24 10.3 3.6 0.41 9.5 3.6 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein NYD-SP28_assoc PF14775.6 ORY08450.1 - 0.41 10.8 2.0 1.5 9.0 2.0 2.0 1 0 0 1 1 1 0 Sperm tail C-terminal domain MFS_1 PF07690.16 ORY08452.1 - 4.3e-29 101.5 15.3 4.3e-29 101.5 15.3 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY08452.1 - 3.9e-05 22.7 9.7 3.9e-05 22.7 9.7 2.8 3 0 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.13 ORY08452.1 - 0.0032 16.0 2.1 0.0032 16.0 2.1 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) ADH_zinc_N PF00107.26 ORY08453.1 - 3.5e-27 94.9 0.0 2.3e-26 92.3 0.0 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ORY08453.1 - 2.1e-22 80.6 0.0 8.4e-22 78.7 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Cu-oxidase_3 PF07732.15 ORY08454.1 - 2.6e-40 137.1 1.1 6.7e-40 135.8 0.2 2.1 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 ORY08454.1 - 2.4e-32 111.6 6.2 7.7e-24 84.0 1.0 3.2 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.22 ORY08454.1 - 3e-19 69.7 0.0 1.6e-18 67.3 0.0 2.2 2 1 0 2 2 2 1 Multicopper oxidase HET PF06985.11 ORY08455.1 - 1.3e-12 48.3 8.9 3e-10 40.6 2.5 2.9 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) NACHT PF05729.12 ORY08455.1 - 1.7e-09 37.8 0.2 4.9e-09 36.3 0.2 1.8 1 0 0 1 1 1 1 NACHT domain RNA_helicase PF00910.22 ORY08455.1 - 0.0019 18.5 0.0 0.0066 16.8 0.0 2.0 1 0 0 1 1 1 1 RNA helicase Ank_3 PF13606.6 ORY08455.1 - 0.0034 17.8 0.2 0.035 14.6 0.0 2.8 3 0 0 3 3 3 1 Ankyrin repeat NB-ARC PF00931.22 ORY08455.1 - 0.0071 15.6 0.2 0.041 13.1 0.2 2.2 1 1 0 1 1 1 1 NB-ARC domain zf_C2H2_13 PF18508.1 ORY08455.1 - 0.0076 15.8 1.1 0.0076 15.8 1.1 1.9 2 0 0 2 2 2 1 Zinc finger domain Ank PF00023.30 ORY08455.1 - 0.017 15.5 0.0 0.057 13.9 0.0 1.9 1 0 0 1 1 1 0 Ankyrin repeat Ank_2 PF12796.7 ORY08455.1 - 0.02 15.5 0.0 0.43 11.2 0.0 2.7 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) AAA PF00004.29 ORY08455.1 - 0.021 15.2 0.0 0.12 12.8 0.0 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 ORY08455.1 - 0.078 13.4 0.0 0.29 11.5 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.6 ORY08455.1 - 0.08 13.0 0.0 0.95 9.5 0.0 2.7 2 1 0 2 2 2 0 AAA domain Ank_5 PF13857.6 ORY08455.1 - 0.082 13.3 0.0 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank_4 PF13637.6 ORY08456.1 - 6.7e-26 90.3 0.1 3.9e-08 33.7 0.0 4.0 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 ORY08456.1 - 6.1e-21 74.8 1.7 1.5e-11 44.7 0.2 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 ORY08456.1 - 3.9e-19 68.2 1.5 0.00075 19.8 0.0 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.6 ORY08456.1 - 4.8e-10 38.8 0.0 0.7 10.6 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 ORY08456.1 - 7.4e-07 29.3 0.1 0.034 14.5 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) YajC PF02699.15 ORY08456.1 - 0.00016 21.5 4.4 3.3 7.7 0.0 4.0 1 1 3 4 4 4 1 Preprotein translocase subunit DUF1843 PF08898.10 ORY08456.1 - 0.016 15.7 7.6 1.7 9.2 0.7 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF1843) MT0933_antitox PF14013.6 ORY08456.1 - 0.042 14.1 9.0 7.5 6.9 0.4 3.5 1 1 2 3 3 3 0 MT0933-like antitoxin protein HicA_toxin PF07927.12 ORY08456.1 - 0.058 13.4 2.6 83 3.3 0.0 3.9 4 0 0 4 4 4 0 HicA toxin of bacterial toxin-antitoxin, SprB PF13573.6 ORY08456.1 - 0.13 12.0 1.4 1.7e+02 2.0 0.0 3.9 4 0 0 4 4 4 0 SprB repeat CK1gamma_C PF12605.8 ORY08456.1 - 0.72 11.1 4.8 47 5.2 0.2 3.0 1 1 2 3 3 3 0 Casein kinase 1 gamma C terminal Ank_4 PF13637.6 ORY08457.1 - 3.5e-19 68.9 0.1 4.9e-09 36.6 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 ORY08457.1 - 1.4e-16 60.1 0.5 0.00054 20.3 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.7 ORY08457.1 - 1.9e-15 57.2 0.7 1.4e-14 54.4 0.6 2.1 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ORY08457.1 - 9.7e-08 31.7 0.0 0.63 10.8 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat YajC PF02699.15 ORY08457.1 - 0.00063 19.6 3.0 0.59 10.0 0.2 3.0 1 1 2 3 3 3 2 Preprotein translocase subunit Ank_5 PF13857.6 ORY08457.1 - 0.00098 19.4 0.0 0.043 14.2 0.0 2.6 1 1 2 3 3 3 2 Ankyrin repeats (many copies) DUF1843 PF08898.10 ORY08457.1 - 0.002 18.6 7.2 0.33 11.5 0.5 3.5 1 1 2 3 3 3 2 Domain of unknown function (DUF1843) FAD_syn PF06574.12 ORY08457.1 - 0.017 15.0 4.4 10 6.0 0.1 3.0 3 0 0 3 3 3 0 FAD synthetase DUF892 PF05974.12 ORY08457.1 - 0.026 14.5 1.4 32 4.5 0.0 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF892) GAPT PF11770.8 ORY08457.1 - 0.064 13.1 0.1 3.2 7.6 0.0 2.1 1 1 1 2 2 2 0 GRB2-binding adapter (GAPT) MT0933_antitox PF14013.6 ORY08457.1 - 0.066 13.5 6.1 9.4 6.6 0.4 3.2 1 1 2 3 3 3 0 MT0933-like antitoxin protein SprB PF13573.6 ORY08457.1 - 0.11 12.3 0.9 23 4.9 0.1 3.0 3 0 0 3 3 3 0 SprB repeat AlaE PF06610.13 ORY08457.1 - 0.18 11.9 0.0 13 5.8 0.0 2.0 1 1 1 2 2 2 0 L-alanine exporter Amdase PF17645.1 ORY08457.1 - 0.19 11.3 3.9 18 4.8 0.1 2.9 1 1 2 3 3 3 0 Arylmalonate decarboxylase Sulfotransfer_4 PF17784.1 ORY08460.1 - 1.5e-33 116.5 2.3 7.2e-25 88.1 0.4 3.0 1 1 1 2 2 2 2 Sulfotransferase domain Sulfotransfer_3 PF13469.6 ORY08460.1 - 0.0045 17.4 0.1 0.0083 16.5 0.0 1.4 1 1 0 1 1 1 1 Sulfotransferase family DUF3717 PF12512.8 ORY08463.1 - 0.0059 16.5 0.1 0.01 15.7 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3717) TPR_7 PF13176.6 ORY08464.1 - 0.0001 22.1 1.7 0.019 15.0 0.0 3.7 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 ORY08464.1 - 0.0006 19.8 0.9 0.017 15.3 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 ORY08464.1 - 0.0019 18.2 1.7 0.37 11.0 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 ORY08464.1 - 0.0029 17.4 0.5 2.2 8.3 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 ORY08464.1 - 0.0068 16.7 6.1 0.35 11.2 0.0 4.2 4 1 2 6 6 6 1 Tetratricopeptide repeat TPR_10 PF13374.6 ORY08464.1 - 0.011 15.6 0.2 0.23 11.4 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 ORY08464.1 - 0.033 13.9 0.7 0.18 11.5 0.0 2.6 3 0 0 3 3 3 0 TPR repeat baeRF_family10 PF18854.1 ORY08464.1 - 0.041 14.1 2.9 0.14 12.4 1.6 2.5 2 1 1 3 3 3 0 Bacterial archaeo-eukaryotic release factor family 10 PBCV_basic_adap PF08789.10 ORY08464.1 - 0.059 13.5 0.1 0.11 12.6 0.1 1.4 1 0 0 1 1 1 0 PBCV-specific basic adaptor domain Peripla_BP_2 PF01497.18 ORY08464.1 - 0.066 12.8 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Periplasmic binding protein DUF4866 PF16160.5 ORY08464.1 - 0.073 12.4 0.1 2.1 7.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4866) TPR_19 PF14559.6 ORY08464.1 - 0.08 13.5 1.2 4 8.0 0.0 3.5 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 ORY08464.1 - 0.1 13.5 11.6 0.91 10.5 0.1 5.3 5 1 0 5 5 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 ORY08464.1 - 0.13 13.0 3.3 46 5.0 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat PrmA PF06325.13 ORY08467.1 - 5e-11 42.5 0.1 1e-10 41.5 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 ORY08467.1 - 2.1e-09 37.4 0.1 3.8e-09 36.5 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY08467.1 - 6.5e-09 36.4 0.4 1.3e-08 35.4 0.1 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY08467.1 - 7.9e-07 29.1 0.0 1.4e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY08467.1 - 3.2e-05 24.5 0.0 7.4e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ORY08467.1 - 4.6e-05 23.0 0.0 7.4e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.19 ORY08467.1 - 0.00025 21.2 0.0 0.00044 20.4 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_12 PF08242.12 ORY08467.1 - 0.00042 21.0 0.0 0.00084 20.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 ORY08467.1 - 0.00043 19.7 0.0 0.00063 19.1 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.7 ORY08467.1 - 0.0033 17.4 0.0 0.0056 16.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain zf-C2H2_2 PF12756.7 ORY08467.1 - 0.0033 17.7 0.1 0.0058 16.9 0.1 1.3 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) Methyltransf_9 PF08003.11 ORY08467.1 - 0.0068 15.4 0.0 0.0096 14.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) NNMT_PNMT_TEMT PF01234.17 ORY08467.1 - 0.038 13.2 0.0 0.065 12.4 0.0 1.3 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family zf-Di19 PF05605.12 ORY08467.1 - 0.062 13.6 0.9 0.11 12.9 0.9 1.4 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Ubie_methyltran PF01209.18 ORY08467.1 - 0.075 12.3 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family PCMT PF01135.19 ORY08467.1 - 0.093 12.5 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Rav1p_C PF12234.8 ORY08468.1 - 2.9e-276 918.0 0.0 4.2e-276 917.5 0.0 1.2 1 0 0 1 1 1 1 RAVE protein 1 C terminal WD40 PF00400.32 ORY08468.1 - 0.00064 20.5 0.8 0.45 11.5 0.0 4.8 5 1 1 6 6 6 1 WD domain, G-beta repeat Yae1_N PF09811.9 ORY08469.1 - 0.0011 18.6 6.5 0.0011 18.6 6.5 3.2 4 0 0 4 4 4 2 Essential protein Yae1, N terminal Erythro-docking PF09277.11 ORY08470.1 - 0.074 13.0 5.4 21 5.1 0.0 4.0 3 0 0 3 3 3 0 Erythronolide synthase, docking YtxH PF12732.7 ORY08471.1 - 0.13 12.8 0.0 0.26 11.8 0.0 1.5 1 0 0 1 1 1 0 YtxH-like protein Glyco_hydro_61 PF03443.14 ORY08473.1 - 1.1e-27 97.3 0.1 1.5e-27 96.9 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 SH3_15 PF18346.1 ORY08473.1 - 0.1 12.9 0.0 2.7 8.4 0.0 2.3 2 0 0 2 2 2 0 Mind bomb SH3 repeat domain PTR2 PF00854.21 ORY08474.1 - 1.1e-79 268.1 10.5 1.5e-79 267.6 10.5 1.1 1 0 0 1 1 1 1 POT family MFS_1 PF07690.16 ORY08474.1 - 2.9e-07 29.7 30.9 3e-07 29.7 27.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4293 PF14126.6 ORY08474.1 - 0.014 15.7 5.1 0.12 12.6 2.8 2.5 1 1 0 2 2 2 0 Domain of unknown function (DUF4293) Fungal_trans PF04082.18 ORY08475.1 - 3e-20 72.4 0.1 5e-20 71.6 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pex14_N PF04695.13 ORY08475.1 - 3.9 8.1 5.3 0.86 10.2 0.0 2.5 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region adh_short_C2 PF13561.6 ORY08476.1 - 4.7e-44 150.7 0.5 5.7e-44 150.4 0.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY08476.1 - 1e-43 149.1 0.3 1.3e-43 148.8 0.3 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORY08476.1 - 6.1e-10 39.3 0.1 7.9e-10 38.9 0.1 1.2 1 0 0 1 1 1 1 KR domain DapB_N PF01113.20 ORY08476.1 - 0.0025 17.9 0.1 0.004 17.3 0.1 1.2 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Epimerase PF01370.21 ORY08476.1 - 0.0025 17.3 0.1 0.0031 17.0 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.17 ORY08476.1 - 0.0044 17.6 0.2 0.0083 16.7 0.2 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 ORY08476.1 - 0.0074 16.5 0.1 0.013 15.8 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain 2-Hacid_dh_C PF02826.19 ORY08476.1 - 0.019 14.3 0.0 0.029 13.7 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 ORY08476.1 - 0.023 14.7 0.0 0.11 12.5 0.0 1.8 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.15 ORY08476.1 - 0.039 13.1 0.1 0.05 12.7 0.1 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein ApbA PF02558.16 ORY08476.1 - 0.05 13.2 0.1 0.083 12.5 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 ORY08476.1 - 0.056 13.3 0.2 0.074 12.9 0.2 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ADH_N PF08240.12 ORY08477.1 - 9e-33 112.4 0.5 9e-33 112.4 0.5 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORY08477.1 - 1.6e-24 86.4 0.2 1.6e-24 86.4 0.2 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 ORY08477.1 - 5.3e-10 39.1 1.0 6.7e-06 25.7 0.1 2.2 2 0 0 2 2 2 2 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 ORY08477.1 - 1.6e-05 25.9 0.1 0.00013 23.0 0.1 2.4 1 1 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 ORY08477.1 - 0.011 15.0 0.5 0.018 14.4 0.5 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 ORY08477.1 - 0.14 11.5 0.1 0.25 10.7 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PRK PF00485.18 ORY08478.1 - 3.8e-07 30.0 0.0 5.6e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.6 ORY08478.1 - 6.2e-05 23.2 0.3 0.0006 20.0 0.3 2.1 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 ORY08478.1 - 7.1e-05 23.4 0.0 0.00018 22.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ORY08478.1 - 8.1e-05 23.1 0.0 0.00012 22.5 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 ORY08478.1 - 0.00013 22.4 0.0 0.0002 21.8 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 ORY08478.1 - 0.00023 20.5 0.5 0.0027 17.0 0.0 2.2 2 0 0 2 2 2 1 Zeta toxin AAA_5 PF07728.14 ORY08478.1 - 0.00066 19.7 0.0 0.0014 18.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 ORY08478.1 - 0.00096 18.9 0.0 0.0016 18.2 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 ORY08478.1 - 0.0032 17.1 0.0 0.0055 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 ORY08478.1 - 0.0063 15.6 0.1 0.0096 15.0 0.1 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein NTPase_1 PF03266.15 ORY08478.1 - 0.0066 16.4 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 NTPase AAA_30 PF13604.6 ORY08478.1 - 0.0083 15.9 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 ORY08478.1 - 0.0093 16.2 0.0 0.02 15.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 ORY08478.1 - 0.0095 15.7 0.2 0.04 13.6 0.0 1.9 2 0 0 2 2 2 1 Cytidylate kinase AAA_22 PF13401.6 ORY08478.1 - 0.0098 16.2 0.0 0.016 15.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 ORY08478.1 - 0.012 14.9 0.0 0.017 14.3 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.22 ORY08478.1 - 0.012 16.0 0.0 0.019 15.4 0.0 1.3 1 0 0 1 1 1 0 RNA helicase AAA_17 PF13207.6 ORY08478.1 - 0.014 15.8 0.0 0.047 14.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 ORY08478.1 - 0.015 15.6 0.0 0.026 14.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 ORY08478.1 - 0.021 14.7 0.0 0.04 13.8 0.0 1.5 1 0 0 1 1 1 0 NACHT domain cobW PF02492.19 ORY08478.1 - 0.043 13.4 0.0 0.063 12.9 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain RecA PF00154.21 ORY08478.1 - 0.054 13.0 0.0 0.075 12.5 0.0 1.1 1 0 0 1 1 1 0 recA bacterial DNA recombination protein ABC_tran PF00005.27 ORY08478.1 - 0.06 13.9 0.0 0.12 12.9 0.0 1.4 1 0 0 1 1 1 0 ABC transporter DUF2075 PF09848.9 ORY08478.1 - 0.069 12.4 0.0 0.077 12.2 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_24 PF13479.6 ORY08478.1 - 0.07 12.8 0.0 0.094 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.20 ORY08478.1 - 0.071 13.0 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase PhoH PF02562.16 ORY08478.1 - 0.072 12.5 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein SRP54 PF00448.22 ORY08478.1 - 0.078 12.6 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_11 PF13086.6 ORY08478.1 - 0.087 12.6 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 ORY08478.1 - 0.1 12.0 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DnaB_C PF03796.15 ORY08478.1 - 0.11 11.8 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain KTI12 PF08433.10 ORY08478.1 - 0.11 11.9 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 TIP49 PF06068.13 ORY08478.1 - 0.14 11.4 0.0 0.19 10.9 0.0 1.1 1 0 0 1 1 1 0 TIP49 P-loop domain TsaE PF02367.17 ORY08478.1 - 0.16 12.0 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE adh_short_C2 PF13561.6 ORY08479.1 - 7.7e-53 179.4 3.6 1.2e-52 178.8 3.6 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY08479.1 - 6.8e-37 126.8 6.1 1.8e-36 125.4 6.1 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORY08479.1 - 5.5e-08 32.9 6.9 4.6e-06 26.7 6.9 2.1 1 1 0 1 1 1 1 KR domain Clp_N PF02861.20 ORY08479.1 - 0.1 12.8 0.2 0.19 11.9 0.2 1.5 1 0 0 1 1 1 0 Clp amino terminal domain, pathogenicity island component 2OG-FeII_Oxy PF03171.20 ORY08480.1 - 1.5e-13 51.1 0.1 2.7e-13 50.3 0.1 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 ORY08480.1 - 6.5e-09 36.6 0.0 1e-08 35.9 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal TFR_dimer PF04253.15 ORY08481.1 - 9.2e-25 87.1 0.0 1.5e-24 86.4 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 ORY08481.1 - 2e-22 79.9 0.0 4e-22 78.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 ORY08481.1 - 1.4e-08 34.7 0.1 3.7e-08 33.3 0.1 1.7 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 ORY08481.1 - 0.041 13.6 0.0 0.066 12.9 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 adh_short PF00106.25 ORY08482.1 - 1.4e-22 80.1 0.5 2.1e-22 79.6 0.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY08482.1 - 2e-12 47.2 0.2 2.9e-12 46.7 0.2 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY08482.1 - 0.00099 19.1 0.0 0.0018 18.2 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ORY08482.1 - 0.0015 18.0 0.1 0.54 9.7 0.1 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 ORY08482.1 - 0.0039 17.1 0.5 0.0067 16.3 0.5 1.6 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 ORY08482.1 - 0.0044 16.6 0.4 0.0076 15.8 0.4 1.3 1 0 0 1 1 1 1 NmrA-like family Abhydrolase_1 PF00561.20 ORY08483.1 - 1.2e-13 51.4 0.1 3.3e-11 43.3 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORY08483.1 - 7.7e-09 36.5 4.1 1e-08 36.1 4.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.11 ORY08483.1 - 0.11 12.4 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Spore_Cse60 PF10957.8 ORY08485.1 - 0.16 12.0 1.2 0.21 11.6 0.0 1.8 2 0 0 2 2 2 0 Sporulation protein Cse60 DUF494 PF04361.13 ORY08486.1 - 0.14 12.1 0.1 0.26 11.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF494) Sugar_tr PF00083.24 ORY08487.1 - 7e-78 262.5 17.8 8.4e-78 262.2 17.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY08487.1 - 1.2e-24 86.9 37.7 1.9e-14 53.4 22.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Peptidase_C14 PF00656.22 ORY08490.1 - 0.11 12.5 0.1 0.39 10.6 0.1 1.8 1 1 0 1 1 1 0 Caspase domain HET PF06985.11 ORY08491.1 - 9.7e-12 45.5 8.9 3.9e-09 37.0 0.8 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Ino80_Iec3 PF14612.6 ORY08492.1 - 1.6e-37 130.5 0.3 1.9e-37 130.2 0.3 1.1 1 0 0 1 1 1 1 IEC3 subunit of the Ino80 complex, chromatin re-modelling DMAP_binding PF06464.11 ORY08492.1 - 0.0063 17.3 0.1 0.026 15.3 0.0 2.1 2 0 0 2 2 2 1 DMAP1-binding Domain ORMDL PF04061.14 ORY08493.1 - 9.6e-58 193.8 2.8 1.1e-57 193.6 2.8 1.0 1 0 0 1 1 1 1 ORMDL family NAD_binding_1 PF00175.21 ORY08496.1 - 0.00026 21.6 0.0 0.00032 21.3 0.0 1.1 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain DUF4267 PF14087.6 ORY08506.1 - 2.2e-17 63.1 5.9 2.6e-17 62.9 5.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) Ras PF00071.22 ORY08507.1 - 3e-27 95.2 0.1 3.5e-27 95.0 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY08507.1 - 7.3e-07 29.4 0.1 1.3e-06 28.7 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Helo_like_N PF17111.5 ORY08508.1 - 6.9e-09 35.4 2.4 4.2e-08 32.8 2.4 2.3 1 1 0 1 1 1 1 Fungal N-terminal domain of STAND proteins RecG_N PF17190.4 ORY08508.1 - 0.0047 17.6 0.0 0.0079 16.9 0.0 1.3 1 0 0 1 1 1 1 RecG N-terminal helical domain DUF948 PF06103.11 ORY08508.1 - 0.0058 16.9 3.2 0.13 12.5 1.1 2.2 1 1 1 2 2 2 2 Bacterial protein of unknown function (DUF948) Zw10 PF06248.13 ORY08508.1 - 0.0086 14.7 0.0 0.02 13.5 0.0 1.5 1 1 1 2 2 2 1 Centromere/kinetochore Zw10 COG2 PF06148.11 ORY08508.1 - 0.028 14.5 0.5 0.13 12.4 0.4 1.9 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 KxDL PF10241.9 ORY08508.1 - 0.087 13.1 0.1 7.5 6.9 0.0 2.3 1 1 1 2 2 2 0 Uncharacterized conserved protein Ribonuc_L-PSP PF01042.21 ORY08508.1 - 0.13 12.3 0.0 0.9 9.6 0.0 2.1 1 1 1 2 2 2 0 Endoribonuclease L-PSP DIOX_N PF14226.6 ORY08509.1 - 6.5e-28 97.9 0.0 1e-27 97.3 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 ORY08509.1 - 2.6e-17 63.2 0.0 4e-17 62.6 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily P53_TAD PF08563.11 ORY08509.1 - 0.36 10.3 1.3 0.69 9.5 1.3 1.5 1 0 0 1 1 1 0 P53 transactivation motif NTP_transferase PF00483.23 ORY08510.1 - 6.1e-32 111.2 0.0 8.1e-32 110.8 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 ORY08510.1 - 3.6e-10 39.2 6.0 1.6e-06 27.6 0.0 3.7 3 1 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 ORY08510.1 - 6.7e-09 36.3 0.0 1e-08 35.7 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.19 ORY08510.1 - 0.076 12.7 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase DUF4954 PF16314.5 ORY08510.1 - 0.13 10.4 0.1 0.23 9.5 0.0 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4954) CTP_transf_3 PF02348.19 ORY08510.1 - 0.14 12.0 0.0 0.38 10.6 0.0 1.6 2 0 0 2 2 2 0 Cytidylyltransferase AGA2 PF17366.2 ORY08510.1 - 0.17 11.6 0.6 0.39 10.4 0.6 1.5 1 0 0 1 1 1 0 A-agglutinin-binding subunit Aga2 DUF1349 PF07081.11 ORY08512.1 - 5.5e-16 58.8 0.0 7.2e-16 58.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) Complex1_30kDa PF00329.19 ORY08513.1 - 1.2e-45 155.1 0.0 1.7e-45 154.6 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit zf-RING_4 PF14570.6 ORY08514.1 - 3.1e-20 71.7 11.9 5.5e-20 70.9 11.9 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RRM_1 PF00076.22 ORY08514.1 - 2.7e-07 30.3 0.0 9e-07 28.6 0.0 2.0 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.6 ORY08514.1 - 3.1e-07 30.2 10.6 6.2e-07 29.2 10.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.12 ORY08514.1 - 0.0014 18.0 2.2 0.0014 18.0 2.2 3.4 3 1 2 5 5 4 1 Rtf2 RING-finger zf-RING_2 PF13639.6 ORY08514.1 - 0.003 17.8 13.6 0.0054 17.0 13.6 1.4 1 0 0 1 1 1 1 Ring finger domain FYVE PF01363.21 ORY08514.1 - 0.021 14.9 5.2 0.049 13.8 5.2 1.6 1 0 0 1 1 1 0 FYVE zinc finger Baculo_IE-1 PF05290.11 ORY08514.1 - 0.027 14.4 5.8 0.048 13.6 5.8 1.3 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) Prok-RING_4 PF14447.6 ORY08514.1 - 0.035 14.0 10.6 0.15 12.0 8.5 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 ORY08514.1 - 0.087 12.7 10.2 0.18 11.7 10.2 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) SET_assoc PF11767.8 ORY08514.1 - 0.12 12.0 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated Rad50_zn_hook PF04423.14 ORY08514.1 - 0.94 9.4 4.4 1.8 8.4 1.7 2.5 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-UDP PF14569.6 ORY08514.1 - 1.3 9.2 7.2 2.9 8.1 7.2 1.5 1 0 0 1 1 1 0 Zinc-binding RING-finger FYVE_2 PF02318.16 ORY08514.1 - 2.5 8.3 10.9 0.3 11.3 6.0 1.9 2 0 0 2 2 2 0 FYVE-type zinc finger zf-RING_5 PF14634.6 ORY08514.1 - 2.7 8.0 13.5 5.3 7.1 13.5 1.5 1 0 0 1 1 1 0 zinc-RING finger domain DUF5523 PF17661.1 ORY08514.1 - 3.2 7.4 0.0 3.2 7.4 0.0 3.3 2 2 1 3 3 2 0 Family of unknown function (DUF5523) zf-CCCH PF00642.24 ORY08516.1 - 2.3e-06 27.4 8.2 2.3e-06 27.4 8.2 2.9 2 1 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 ORY08516.1 - 2.8e-06 27.0 7.8 2.8e-06 27.0 7.8 2.7 4 0 0 4 4 4 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 ORY08516.1 - 0.00018 21.4 11.5 0.00018 21.4 11.5 2.9 3 0 0 3 3 3 1 Zinc finger domain Torus PF16131.5 ORY08516.1 - 0.0054 17.4 7.0 0.0054 17.4 7.0 2.4 2 1 0 2 2 2 1 Torus domain Helo_like_N PF17111.5 ORY08517.1 - 3.5e-12 46.2 3.2 7.3e-12 45.1 3.2 1.5 1 1 0 1 1 1 1 Fungal N-terminal domain of STAND proteins SesA PF17107.5 ORY08517.1 - 2e-05 24.7 1.7 3e-05 24.2 0.1 2.1 2 1 0 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases LIM PF00412.22 ORY08517.1 - 0.00062 19.9 4.6 0.00062 19.9 4.6 3.2 2 1 1 3 3 3 1 LIM domain BORCS8 PF10167.9 ORY08517.1 - 0.0084 16.0 2.2 0.05 13.5 0.7 2.3 2 0 0 2 2 2 1 BLOC-1-related complex sub-unit 8 E2R135 PF11570.8 ORY08517.1 - 0.019 15.2 0.2 0.038 14.3 0.2 1.5 1 0 0 1 1 1 0 Coiled-coil receptor-binding R-domain of colicin E2 SPT16 PF08644.11 ORY08517.1 - 0.18 12.0 1.1 0.36 11.0 1.1 1.5 1 0 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) Not3 PF04065.15 ORY08517.1 - 0.29 10.5 5.2 0.67 9.3 5.2 1.5 1 1 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component Prenyltransf PF01255.19 ORY08517.1 - 0.35 10.4 2.8 1.4 8.4 2.8 1.8 1 1 0 1 1 1 0 Putative undecaprenyl diphosphate synthase E1_dh PF00676.20 ORY08518.1 - 1.1e-86 290.5 0.0 1.5e-86 290.1 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 ORY08518.1 - 0.00054 19.8 0.1 0.0034 17.2 0.1 2.1 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain XFP_N PF09364.10 ORY08518.1 - 0.019 13.8 0.4 0.13 11.1 0.0 2.3 3 0 0 3 3 3 0 XFP N-terminal domain DXP_synthase_N PF13292.6 ORY08518.1 - 0.059 12.6 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase Ubie_methyltran PF01209.18 ORY08519.1 - 1.1e-79 267.1 0.0 1.6e-79 266.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 ORY08519.1 - 9.6e-16 58.3 0.0 2.1e-15 57.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY08519.1 - 6.6e-13 49.1 0.0 1.6e-12 47.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY08519.1 - 1.1e-12 48.0 0.0 1.7e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY08519.1 - 8.5e-09 36.1 0.0 1.4e-08 35.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY08519.1 - 1.1e-05 25.3 0.0 1.8e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DUF747 PF05346.11 ORY08520.1 - 1.5e-123 412.3 2.4 1.9e-123 412.0 2.4 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family PEPCK_ATP PF01293.20 ORY08521.1 - 7.7e-216 717.2 0.0 9.3e-216 716.9 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_16 PF13191.6 ORY08521.1 - 0.14 12.5 0.0 0.26 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 ORY08521.1 - 0.15 12.2 0.3 0.4 10.8 0.1 1.8 2 0 0 2 2 2 0 AAA domain ABC2_membrane PF01061.24 ORY08522.1 - 1e-17 64.3 4.1 1.3e-17 63.9 4.1 1.0 1 0 0 1 1 1 1 ABC-2 type transporter ABC2_membrane PF01061.24 ORY08523.1 - 3.2e-48 163.9 19.4 3.2e-48 163.9 19.4 1.8 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 ORY08523.1 - 9e-36 123.4 0.0 2.1e-16 60.7 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 ORY08523.1 - 2.5e-27 94.6 0.1 2.5e-27 94.6 0.1 2.2 2 0 0 2 2 1 1 CDR ABC transporter ABC_trans_N PF14510.6 ORY08523.1 - 5.7e-13 49.3 0.2 5.7e-13 49.3 0.2 2.6 3 0 0 3 3 1 1 ABC-transporter N-terminal RsgA_GTPase PF03193.16 ORY08523.1 - 8.6e-07 29.0 0.0 1.3e-05 25.2 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_18 PF13238.6 ORY08523.1 - 2e-05 25.2 0.0 0.0057 17.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.7 ORY08523.1 - 2.3e-05 23.7 20.3 3.5e-05 23.1 20.3 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_16 PF13191.6 ORY08523.1 - 0.00012 22.5 0.1 0.0047 17.3 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 ORY08523.1 - 0.00031 20.4 0.1 0.012 15.2 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 ORY08523.1 - 0.00037 20.8 0.2 0.055 13.8 0.1 2.7 2 1 0 2 2 2 1 AAA domain AAA_21 PF13304.6 ORY08523.1 - 0.00088 19.2 0.0 0.21 11.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 ORY08523.1 - 0.001 18.7 0.2 0.12 12.2 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_17 PF13207.6 ORY08523.1 - 0.0015 19.0 0.5 0.066 13.6 0.0 2.9 3 0 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.23 ORY08523.1 - 0.0033 17.5 0.0 0.23 11.5 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_28 PF13521.6 ORY08523.1 - 0.0053 17.0 0.1 0.017 15.3 0.1 1.9 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 ORY08523.1 - 0.015 15.4 0.0 0.26 11.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 ORY08523.1 - 0.018 15.6 1.3 0.51 10.8 0.1 2.8 3 1 0 3 3 2 0 AAA domain cobW PF02492.19 ORY08523.1 - 0.019 14.5 0.1 0.11 12.1 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 ORY08523.1 - 0.024 14.3 0.3 0.64 9.7 0.1 2.7 3 0 0 3 3 3 0 AAA domain NACHT PF05729.12 ORY08523.1 - 0.053 13.4 0.9 0.25 11.2 0.1 2.3 2 0 0 2 2 2 0 NACHT domain RNA_helicase PF00910.22 ORY08523.1 - 0.079 13.3 0.0 2.6 8.5 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_24 PF13479.6 ORY08523.1 - 0.088 12.5 0.0 0.74 9.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 ORY08523.1 - 0.12 12.4 0.4 0.52 10.3 0.2 2.0 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF383 PF04063.14 ORY08523.1 - 0.19 11.4 0.0 0.38 10.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF383) dNK PF01712.19 ORY08523.1 - 0.19 11.6 0.0 0.49 10.2 0.0 1.6 1 0 0 1 1 1 0 Deoxynucleoside kinase FtsK_SpoIIIE PF01580.18 ORY08523.1 - 0.2 11.0 0.1 3.9 6.8 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family E1-E2_ATPase PF00122.20 ORY08525.1 - 3.9e-41 140.6 0.7 3.9e-41 140.6 0.7 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 ORY08525.1 - 8.7e-22 78.4 0.2 1.5e-21 77.6 0.2 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 ORY08525.1 - 0.00012 21.9 0.1 0.00029 20.7 0.1 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 ORY08525.1 - 0.0024 18.3 0.0 0.0062 16.9 0.0 1.8 1 0 0 1 1 1 1 Heavy-metal-associated domain Rad4 PF03835.15 ORY08526.1 - 7.3e-34 116.6 0.1 1.5e-33 115.5 0.1 1.5 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.9 ORY08526.1 - 2.1e-27 95.3 0.2 3.9e-27 94.5 0.2 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 ORY08526.1 - 3.8e-22 77.8 1.2 5.5e-22 77.3 0.3 1.8 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 ORY08526.1 - 7e-17 62.1 0.0 7e-17 62.1 0.0 3.3 3 1 0 3 3 3 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.19 ORY08526.1 - 0.00059 20.3 0.1 0.0032 17.9 0.1 2.2 1 1 0 1 1 1 1 Transglutaminase-like superfamily CaATP_NAI PF12515.8 ORY08526.1 - 0.077 12.6 0.8 0.17 11.5 0.1 2.0 2 0 0 2 2 2 0 Ca2+-ATPase N terminal autoinhibitory domain Gln-synt_C PF00120.24 ORY08528.1 - 0.047 12.7 0.1 0.078 12.0 0.1 1.2 1 0 0 1 1 1 0 Glutamine synthetase, catalytic domain YabA PF06156.13 ORY08528.1 - 0.09 13.4 1.5 9 7.0 0.4 2.4 2 0 0 2 2 2 0 Initiation control protein YabA TAF6_C PF07571.13 ORY08528.1 - 0.18 12.2 0.1 0.89 9.9 0.0 2.1 2 0 0 2 2 2 0 TAF6 C-terminal HEAT repeat domain PRKG1_interact PF15898.5 ORY08528.1 - 0.32 11.9 4.6 1.7 9.6 1.0 2.4 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain APG6_N PF17675.1 ORY08528.1 - 0.51 10.9 4.6 0.78 10.3 3.1 1.9 2 0 0 2 2 2 0 Apg6 coiled-coil region DUF3391 PF11871.8 ORY08528.1 - 7 7.2 8.4 0.39 11.2 0.8 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF3391) Velvet PF11754.8 ORY08529.1 - 1.5e-41 143.0 8.2 1.5e-31 110.2 0.1 3.0 2 1 1 3 3 3 2 Velvet factor p450 PF00067.22 ORY08531.1 - 7.4e-38 130.5 0.0 9.9e-38 130.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MOZ_SAS PF01853.18 ORY08532.1 - 1.1e-75 253.2 0.0 1.6e-75 252.7 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 ORY08532.1 - 4.6e-17 61.4 1.9 1.4e-16 59.8 1.9 1.8 1 0 0 1 1 1 1 MYST family zinc finger domain PHD_4 PF16866.5 ORY08532.1 - 7e-10 38.9 6.6 7e-10 38.9 6.6 2.2 2 0 0 2 2 2 1 PHD-finger PHD PF00628.29 ORY08532.1 - 0.004 17.0 7.0 0.004 17.0 7.0 2.5 2 0 0 2 2 2 1 PHD-finger Acetyltransf_7 PF13508.7 ORY08532.1 - 0.0063 16.9 0.0 0.014 15.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain C1_1 PF00130.22 ORY08532.1 - 0.015 15.2 0.1 0.015 15.2 0.1 2.4 4 0 0 4 4 4 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF3915 PF13054.6 ORY08532.1 - 0.082 12.9 3.6 0.34 10.9 3.6 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) PHD_2 PF13831.6 ORY08532.1 - 2.3 7.9 5.0 1.8 8.2 0.9 2.5 2 0 0 2 2 2 0 PHD-finger MWFE PF15879.5 ORY08533.1 - 7.5e-26 90.1 0.2 9.3e-26 89.8 0.2 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase MWFE subunit Acetyltransf_2 PF00797.17 ORY08534.1 - 6.3e-43 147.3 0.0 8.6e-43 146.9 0.0 1.1 1 0 0 1 1 1 1 N-acetyltransferase Uds1 PF15456.6 ORY08535.1 - 3e-38 130.9 2.7 3e-38 130.9 2.7 6.4 6 1 1 7 7 7 3 Up-regulated During Septation APG6_N PF17675.1 ORY08535.1 - 0.0062 17.1 15.3 0.0062 17.1 15.3 7.7 4 2 3 7 7 7 1 Apg6 coiled-coil region NACHT_sigma PF17106.5 ORY08536.1 - 6e-05 23.1 9.1 9e-05 22.5 9.1 1.3 1 0 0 1 1 1 1 Sigma domain on NACHT-NTPases Melibiase_2 PF16499.5 ORY08538.1 - 5.3e-57 193.2 5.0 1.3e-56 191.9 5.0 1.7 1 1 0 1 1 1 1 Alpha galactosidase A Ricin_B_lectin PF00652.22 ORY08538.1 - 3.6e-16 59.6 2.6 6.4e-16 58.8 2.6 1.5 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Melibiase_C PF17801.1 ORY08538.1 - 6e-16 58.3 0.2 8.7e-15 54.6 0.0 2.7 3 0 0 3 3 3 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 ORY08538.1 - 7e-05 21.9 0.0 0.00014 21.0 0.0 1.4 1 0 0 1 1 1 1 Melibiase RicinB_lectin_2 PF14200.6 ORY08538.1 - 0.00042 21.0 1.7 0.011 16.5 0.5 2.9 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like CDtoxinA PF03498.14 ORY08538.1 - 0.013 15.0 1.9 0.2 11.2 0.5 2.6 1 1 1 2 2 2 0 Cytolethal distending toxin A/C domain Rep_fac-A_C PF08646.10 ORY08538.1 - 0.12 12.1 0.8 1.1 9.0 0.3 2.2 2 0 0 2 2 2 0 Replication factor-A C terminal domain Ccdc124 PF06244.12 ORY08539.1 - 6.9e-26 91.3 24.6 6.9e-26 91.3 24.6 2.7 2 1 0 2 2 2 1 Coiled-coil domain-containing protein 124 /Oxs1 Glyco_hydro_76 PF03663.14 ORY08540.1 - 5.6e-118 394.6 16.1 1.2e-117 393.5 16.1 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 ORY08540.1 - 0.7 8.9 8.1 0.36 9.8 0.5 2.4 1 1 1 2 2 2 0 Glycosyl Hydrolase Family 88 Acyltransferase PF01553.21 ORY08541.1 - 3.2e-11 43.0 0.0 5.1e-10 39.1 0.0 2.4 1 1 0 1 1 1 1 Acyltransferase TPR_12 PF13424.6 ORY08542.1 - 2.4e-100 329.0 69.3 5.8e-17 61.8 2.8 7.3 4 1 5 9 9 9 8 Tetratricopeptide repeat TPR_10 PF13374.6 ORY08542.1 - 1.9e-90 294.6 40.9 3.4e-11 42.6 0.3 10.3 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_1 PF00515.28 ORY08542.1 - 1.1e-43 145.3 37.8 4.9e-05 23.0 0.4 11.0 11 0 0 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.17 ORY08542.1 - 8.9e-33 109.8 34.4 0.0012 18.8 0.2 11.1 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_8 PF13181.6 ORY08542.1 - 5.3e-32 107.3 22.2 0.0011 19.0 0.1 11.3 11 0 0 11 11 11 8 Tetratricopeptide repeat TPR_MalT PF17874.1 ORY08542.1 - 1.2e-30 107.1 18.0 7e-10 38.8 2.0 5.0 1 1 3 4 4 4 4 MalT-like TPR region TPR_7 PF13176.6 ORY08542.1 - 3.4e-28 95.6 29.2 0.011 15.7 0.1 11.1 11 0 0 11 11 11 8 Tetratricopeptide repeat TPR_14 PF13428.6 ORY08542.1 - 1.5e-24 84.6 27.7 0.015 16.0 0.1 10.7 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_4 PF07721.14 ORY08542.1 - 3.9e-22 76.5 10.8 0.072 13.7 0.0 9.9 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_16 PF13432.6 ORY08542.1 - 2.3e-16 60.2 54.1 0.00068 20.2 4.4 8.7 7 4 0 7 7 5 5 Tetratricopeptide repeat NB-ARC PF00931.22 ORY08542.1 - 5.2e-11 42.2 0.0 2.2e-10 40.2 0.0 1.9 1 1 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 ORY08542.1 - 2.6e-09 37.7 0.3 9.6e-09 35.8 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain TPR_19 PF14559.6 ORY08542.1 - 1.8e-08 34.8 36.6 0.04 14.4 0.9 7.2 2 2 4 7 7 7 6 Tetratricopeptide repeat TPR_17 PF13431.6 ORY08542.1 - 5.1e-08 32.8 31.4 1.1 9.8 0.3 10.5 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_21 PF09976.9 ORY08542.1 - 6.1e-07 29.3 37.6 2.4 7.8 0.0 9.4 2 1 5 8 8 8 2 Tetratricopeptide repeat-like domain RPN7 PF10602.9 ORY08542.1 - 2.4e-05 24.1 8.3 11 5.7 0.1 7.0 1 1 6 8 8 8 0 26S proteasome subunit RPN7 DUF2225 PF09986.9 ORY08542.1 - 2.4e-05 24.2 2.3 0.021 14.6 0.1 3.7 1 1 1 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2225) PPR PF01535.20 ORY08542.1 - 3e-05 24.0 1.0 35 4.9 0.0 6.9 7 0 0 7 7 6 0 PPR repeat ATPase_2 PF01637.18 ORY08542.1 - 0.00073 19.5 0.0 0.0012 18.8 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea SPO22 PF08631.10 ORY08542.1 - 0.0092 15.5 3.7 6.3 6.2 0.0 5.8 7 0 0 7 7 7 1 Meiosis protein SPO22/ZIP4 like TPR_11 PF13414.6 ORY08542.1 - 0.011 15.5 46.4 2.3 8.0 0.5 9.2 9 0 0 9 9 9 0 TPR repeat AAA_22 PF13401.6 ORY08542.1 - 0.016 15.5 0.0 0.054 13.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain DUF4388 PF14332.6 ORY08542.1 - 0.026 14.8 0.4 1e+02 3.3 0.2 5.6 2 2 0 2 2 2 0 Domain of unknown function (DUF4388) HET PF06985.11 ORY08542.1 - 0.079 13.3 0.2 0.36 11.2 0.1 2.2 2 0 0 2 2 1 0 Heterokaryon incompatibility protein (HET) TniB PF05621.11 ORY08542.1 - 0.09 12.2 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein DUF630 PF04783.12 ORY08542.1 - 0.2 11.9 14.1 66 3.8 0.0 7.3 8 0 0 8 8 8 0 Protein of unknown function (DUF630) Hemerythrin PF01814.23 ORY08543.1 - 2.4e-08 34.6 0.0 3.3e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain CDC45 PF02724.14 ORY08544.1 - 1.6e-239 796.5 0.0 2.1e-239 796.1 0.0 1.3 1 0 0 1 1 1 1 CDC45-like protein FAM60A PF15396.6 ORY08544.1 - 0.3 11.1 6.5 0.034 14.1 1.9 1.7 2 0 0 2 2 2 0 Protein Family FAM60A BUD22 PF09073.10 ORY08544.1 - 0.5 9.7 23.6 0.19 11.0 10.5 2.4 2 0 0 2 2 2 0 BUD22 RR_TM4-6 PF06459.12 ORY08544.1 - 8.8 6.1 12.6 0.53 10.1 6.6 1.8 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 MIP PF00230.20 ORY08545.1 - 3e-43 148.2 0.0 5e-43 147.4 0.0 1.3 1 1 0 1 1 1 1 Major intrinsic protein OPT PF03169.15 ORY08547.1 - 1.2e-158 529.6 22.5 1.4e-158 529.4 22.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Phage_holin_2_1 PF04971.12 ORY08547.1 - 0.017 15.1 0.0 0.076 13.0 0.0 2.2 1 0 0 1 1 1 0 Bacteriophage P21 holin S MscL PF01741.18 ORY08547.1 - 0.4 11.0 2.4 6.3 7.1 0.1 3.2 3 0 0 3 3 3 0 Large-conductance mechanosensitive channel, MscL DUF4212 PF13937.6 ORY08547.1 - 7 7.1 10.7 3.2 8.2 0.1 4.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4212) Peptidase_C13 PF01650.18 ORY08548.1 - 5.2e-42 144.1 0.1 6.6e-42 143.8 0.1 1.1 1 0 0 1 1 1 1 Peptidase C13 family Sod_Fe_C PF02777.18 ORY08549.1 - 5.3e-37 126.1 1.2 6.1e-37 125.9 0.3 1.6 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 ORY08549.1 - 1.7e-30 105.3 2.0 2.8e-30 104.6 2.0 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Acetyltransf_8 PF13523.6 ORY08550.1 - 1.2e-49 167.7 0.0 1.8e-49 167.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 ORY08550.1 - 0.084 13.5 0.0 0.15 12.7 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Amidohydro_1 PF01979.20 ORY08552.1 - 4.3e-05 23.0 0.0 5.3e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 ORY08552.1 - 0.00052 19.6 0.1 0.11 11.9 0.1 2.3 2 0 0 2 2 2 2 Amidohydrolase family SWIB PF02201.18 ORY08553.1 - 4.6e-22 77.7 0.0 8.2e-22 76.9 0.0 1.4 1 0 0 1 1 1 1 SWIB/MDM2 domain Aminotran_1_2 PF00155.21 ORY08554.1 - 2.4e-34 119.1 0.0 2.7e-34 118.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II RANK_CRD_2 PF18278.1 ORY08554.1 - 0.17 12.1 0.0 0.58 10.3 0.0 1.9 2 0 0 2 2 2 0 Receptor activator of the NF-KB cysteine-rich repeat domain 2 Aminotran_3 PF00202.21 ORY08554.1 - 0.22 10.1 0.0 0.36 9.4 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-III HA2 PF04408.23 ORY08572.1 - 8.7e-18 64.6 0.0 1.9e-17 63.5 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 ORY08572.1 - 2.8e-17 62.8 0.0 5.8e-17 61.8 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 ORY08572.1 - 1.2e-12 48.1 0.0 3e-12 46.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RWD PF05773.22 ORY08572.1 - 8.1e-11 42.2 0.0 1.5e-10 41.4 0.0 1.5 1 0 0 1 1 1 1 RWD domain DEAD PF00270.29 ORY08572.1 - 4.7e-09 36.2 0.0 9.3e-09 35.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase UBA PF00627.31 ORY08572.1 - 2.1e-05 24.3 0.4 0.16 11.9 0.0 2.8 2 0 0 2 2 2 2 UBA/TS-N domain AAA_22 PF13401.6 ORY08572.1 - 0.036 14.3 3.6 0.47 10.7 3.6 2.4 1 1 0 1 1 1 0 AAA domain ATPase PF06745.13 ORY08572.1 - 0.1 11.9 0.1 0.2 11.0 0.1 1.4 1 0 0 1 1 1 0 KaiC AAA_29 PF13555.6 ORY08572.1 - 0.1 12.3 0.3 0.6 9.9 0.0 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain MA3 PF02847.17 ORY08573.1 - 0.081 12.9 0.2 0.81 9.7 0.1 2.2 2 0 0 2 2 2 0 MA3 domain DUF1308 PF07000.11 ORY08574.1 - 1.2e-09 38.3 0.0 9.9e-09 35.3 0.0 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1308) Syntaxin_2 PF14523.6 ORY08574.1 - 0.05 14.0 0.8 0.12 12.8 0.1 2.0 2 0 0 2 2 2 0 Syntaxin-like protein DUF5645 PF18713.1 ORY08574.1 - 0.084 13.2 0.2 0.17 12.2 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5645) SRP9-21 PF05486.12 ORY08575.1 - 3.3e-32 110.7 0.5 4.7e-32 110.3 0.5 1.2 1 0 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) Pkinase PF00069.25 ORY08577.1 - 1.6e-36 126.1 0.0 1.6e-36 126.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY08577.1 - 5e-28 98.1 0.0 5.6e-28 97.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Cullin PF00888.22 ORY08578.1 - 1.2e-177 592.2 0.2 1.5e-177 592.0 0.2 1.0 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 ORY08578.1 - 7.2e-22 77.2 0.1 2.1e-21 75.7 0.1 1.9 1 0 0 1 1 1 1 Cullin protein neddylation domain Dynamin_N PF00350.23 ORY08580.1 - 7e-45 153.1 0.0 1.4e-44 152.1 0.0 1.5 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 ORY08580.1 - 4.7e-10 39.2 0.1 1.4e-09 37.6 0.1 1.8 1 0 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.23 ORY08580.1 - 1.2e-05 25.4 0.0 0.0003 20.8 0.0 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 ORY08580.1 - 0.0088 16.4 0.1 0.074 13.4 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 ORY08580.1 - 0.072 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 ORY08580.1 - 0.086 12.5 0.4 0.21 11.3 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_28 PF13521.6 ORY08580.1 - 0.09 13.0 0.1 1.2 9.4 0.0 2.7 3 0 0 3 3 3 0 AAA domain PetG PF02529.15 ORY08581.1 - 0.065 13.1 0.5 0.12 12.3 0.5 1.4 1 0 0 1 1 1 0 Cytochrome B6-F complex subunit 5 UreD PF01774.17 ORY08582.1 - 3.4e-75 252.6 0.1 4.1e-75 252.4 0.1 1.1 1 0 0 1 1 1 1 UreD urease accessory protein RasGAP PF00616.19 ORY08583.1 - 0.16 11.7 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 GTPase-activator protein for Ras-like GTPase CbiM PF01891.16 ORY08583.1 - 0.26 11.1 2.8 0.19 11.5 0.3 1.9 2 0 0 2 2 2 0 Cobalt uptake substrate-specific transmembrane region HET PF06985.11 ORY08584.1 - 3.1e-23 82.7 0.0 6.5e-23 81.7 0.0 1.6 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ketoacyl-synt PF00109.26 ORY08585.1 - 1e-74 251.3 0.0 1.7e-74 250.6 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 ORY08585.1 - 2e-58 197.3 0.1 7.9e-58 195.3 0.0 2.1 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.21 ORY08585.1 - 9.7e-49 166.6 0.0 2.3e-48 165.3 0.0 1.6 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 ORY08585.1 - 8.8e-39 133.5 0.0 1.5e-38 132.7 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 ORY08585.1 - 3.6e-36 123.8 0.0 9.8e-36 122.4 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 ORY08585.1 - 1.2e-17 64.5 0.0 2.9e-17 63.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.26 ORY08585.1 - 1.8e-16 60.3 0.0 4.8e-16 58.9 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase KAsynt_C_assoc PF16197.5 ORY08585.1 - 3.3e-15 56.5 0.0 1.1e-14 54.8 0.0 2.0 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N_2 PF13602.6 ORY08585.1 - 3.9e-14 53.8 0.0 5.9e-13 50.0 0.0 2.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.6 ORY08585.1 - 1.1e-10 41.7 0.0 3.6e-10 39.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain adh_short PF00106.25 ORY08585.1 - 5.3e-09 35.8 0.0 4.2e-08 32.9 0.0 2.3 2 0 0 2 2 2 1 short chain dehydrogenase Methyltransf_11 PF08241.12 ORY08585.1 - 1.1e-08 35.6 0.0 2.6e-08 34.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY08585.1 - 2.5e-08 34.5 0.0 7.9e-08 32.9 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY08585.1 - 7.7e-06 25.8 0.0 2.9e-05 23.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.23 ORY08585.1 - 1.1e-05 24.9 0.3 2.4e-05 23.8 0.3 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain ADH_N PF08240.12 ORY08585.1 - 2.1e-05 24.4 0.1 5.4e-05 23.0 0.1 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.25 ORY08585.1 - 3.4e-05 24.1 0.1 7.9e-05 22.9 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short_C2 PF13561.6 ORY08585.1 - 4.3e-05 23.2 0.0 0.00012 21.7 0.0 1.7 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Ubie_methyltran PF01209.18 ORY08585.1 - 0.0039 16.6 0.0 0.0078 15.6 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family ACP_syn_III PF08545.10 ORY08585.1 - 0.029 14.2 0.6 0.092 12.6 0.6 1.9 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Methyltransf_2 PF00891.18 ORY08585.1 - 0.047 13.0 0.0 0.1 11.9 0.0 1.5 1 0 0 1 1 1 0 O-methyltransferase domain DREV PF05219.12 ORY08585.1 - 0.076 12.1 0.0 0.15 11.1 0.0 1.4 1 0 0 1 1 1 0 DREV methyltransferase MFS_1 PF07690.16 ORY08586.1 - 2.9e-35 121.8 44.3 2.2e-33 115.7 44.3 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 ORY08586.1 - 7.4e-14 51.1 20.0 9.2e-14 50.8 20.0 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 ORY08586.1 - 2.9e-11 42.9 10.7 2.9e-11 42.9 10.7 2.6 3 0 0 3 3 3 2 Sugar (and other) transporter Sulfotransfer_4 PF17784.1 ORY08588.1 - 4.7e-70 235.8 0.0 5.9e-70 235.4 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 ORY08588.1 - 0.00017 22.1 0.6 0.0012 19.3 0.0 2.2 1 1 1 2 2 2 1 Sulfotransferase family CTI PF06934.11 ORY08588.1 - 0.0087 14.6 0.2 0.011 14.2 0.2 1.1 1 0 0 1 1 1 1 Fatty acid cis/trans isomerase (CTI) gag-asp_proteas PF13975.6 ORY08592.1 - 0.0018 18.8 0.0 0.91 10.1 0.0 2.8 3 0 0 3 3 3 2 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 ORY08592.1 - 0.049 13.4 0.0 5.2 6.9 0.0 2.3 2 0 0 2 2 2 0 Aspartyl protease Baculo_p24 PF05073.12 ORY08592.1 - 0.055 13.2 0.1 0.084 12.6 0.1 1.3 1 0 0 1 1 1 0 Baculovirus P24 capsid protein Asp_protease_2 PF13650.6 ORY08592.1 - 0.067 13.8 0.0 0.28 11.9 0.0 2.0 1 1 0 1 1 1 0 Aspartyl protease RVP_2 PF08284.11 ORY08592.1 - 0.14 11.9 0.1 16 5.3 0.0 2.2 2 0 0 2 2 2 0 Retroviral aspartyl protease Pyridox_ox_2 PF12900.7 ORY08593.1 - 0.093 12.7 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase AtuA PF07287.11 ORY08594.1 - 5.6e-125 416.7 0.6 6.8e-125 416.4 0.6 1.1 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA F-box PF00646.33 ORY08595.1 - 1.2e-07 31.4 0.1 2.9e-07 30.2 0.1 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 ORY08595.1 - 0.00039 20.2 0.1 0.001 18.9 0.1 1.7 1 0 0 1 1 1 1 F-box-like MFS_1 PF07690.16 ORY08596.1 - 2.6e-27 95.7 57.0 2.6e-27 95.7 57.0 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 ORY08596.1 - 2.2e-07 29.7 22.0 4.4e-07 28.7 22.0 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 ORY08596.1 - 9.8e-06 24.7 14.3 9.8e-06 24.7 14.3 2.6 1 1 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 ORY08596.1 - 0.0028 16.0 3.6 0.0093 14.3 3.6 1.9 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family Methyltransf_25 PF13649.6 ORY08597.1 - 0.0005 20.7 0.1 0.0025 18.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY08597.1 - 0.0073 16.9 0.1 0.022 15.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain OmpA PF00691.20 ORY08597.1 - 0.034 14.5 0.1 0.061 13.7 0.1 1.3 1 0 0 1 1 1 0 OmpA family Methyltransf_12 PF08242.12 ORY08597.1 - 0.037 14.8 0.1 0.11 13.3 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Aldedh PF00171.22 ORY08598.1 - 6.9e-152 506.2 0.0 7.8e-152 506.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 ORY08598.1 - 0.0033 16.5 0.1 0.006 15.7 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.11 ORY08598.1 - 0.058 12.8 0.0 0.3 10.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) DUF1612 PF07756.12 ORY08598.1 - 0.077 13.2 0.0 0.31 11.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1612) tRNA-synt_1b PF00579.25 ORY08599.1 - 3.5e-11 43.0 0.0 2.3e-10 40.3 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) DAO PF01266.24 ORY08600.1 - 4.9e-46 157.9 2.1 6.2e-46 157.6 2.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ORY08600.1 - 9.9e-05 22.5 1.5 0.00016 21.8 0.5 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 ORY08600.1 - 0.0087 16.1 0.7 0.37 10.8 0.3 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 ORY08600.1 - 0.017 14.4 0.4 0.031 13.5 0.4 1.4 1 0 0 1 1 1 0 FAD binding domain MCRA PF06100.11 ORY08600.1 - 0.037 12.8 0.0 0.047 12.5 0.0 1.1 1 0 0 1 1 1 0 MCRA family Pyr_redox_3 PF13738.6 ORY08600.1 - 0.063 12.5 0.3 6.8 5.8 0.9 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DIT1_PvcA PF05141.12 ORY08601.1 - 2.4e-75 253.5 0.0 2.9e-75 253.3 0.0 1.0 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein Glyco_transf_29 PF00777.18 ORY08601.1 - 0.038 13.4 0.0 0.058 12.8 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 29 (sialyltransferase) MFS_1 PF07690.16 ORY08602.1 - 2.2e-36 125.5 19.0 3.2e-36 125.0 18.1 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF2934 PF11154.8 ORY08602.1 - 0.065 12.9 0.1 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2934) DUF1230 PF06799.11 ORY08602.1 - 0.14 12.3 3.7 0.87 9.7 0.0 3.1 3 0 0 3 3 3 0 Conserved in the green lineage and diatoms 27 Transglut_core PF01841.19 ORY08603.1 - 0.15 12.5 0.0 0.51 10.8 0.0 1.9 1 1 0 1 1 1 0 Transglutaminase-like superfamily SIT PF15330.6 ORY08605.1 - 0.028 14.9 0.0 0.044 14.2 0.0 1.3 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT FixS PF03597.15 ORY08605.1 - 0.036 13.8 0.0 0.076 12.7 0.0 1.5 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type GMC_oxred_N PF00732.19 ORY08612.1 - 3.8e-59 200.5 0.0 4.7e-59 200.2 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 ORY08612.1 - 8.7e-27 94.4 0.0 1.8e-26 93.4 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 ORY08612.1 - 6.6e-07 28.8 0.0 0.00062 19.0 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.6 ORY08612.1 - 1.3e-06 27.9 0.0 0.00022 20.6 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ORY08612.1 - 0.00014 21.6 0.1 0.00077 19.1 0.1 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ORY08612.1 - 0.00023 21.3 0.1 0.00051 20.2 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 ORY08612.1 - 0.00077 18.8 0.0 0.0012 18.1 0.0 1.2 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 ORY08612.1 - 0.001 18.3 0.0 0.0028 16.9 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 ORY08612.1 - 0.0016 17.6 0.0 0.0024 17.0 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.14 ORY08612.1 - 0.0018 17.0 0.0 0.0028 16.4 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein TrkA_N PF02254.18 ORY08612.1 - 0.015 15.5 0.0 0.03 14.6 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain ATPase PF06745.13 ORY08612.1 - 0.19 11.1 0.1 0.3 10.4 0.1 1.2 1 0 0 1 1 1 0 KaiC Imm3 PF14425.6 ORY08613.1 - 0.16 12.1 0.3 0.3 11.1 0.3 1.4 1 0 0 1 1 1 0 Immunity protein Imm3 GAS PF13851.6 ORY08613.1 - 0.17 11.2 2.9 0.26 10.6 2.9 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding p450 PF00067.22 ORY08614.1 - 3.8e-42 144.6 0.0 3.2e-41 141.5 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 Glyco_hydro_3_C PF01915.22 ORY08615.1 - 2.3e-50 171.4 0.1 3.4e-50 170.8 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 ORY08615.1 - 3e-31 109.0 0.0 1.2e-30 107.0 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 ORY08615.1 - 7.9e-24 83.6 0.1 1.4e-23 82.7 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain HeLo PF14479.6 ORY08616.1 - 2e-14 53.9 0.2 2.4e-14 53.7 0.2 1.0 1 0 0 1 1 1 1 Prion-inhibition and propagation ZU5 PF00791.20 ORY08616.1 - 0.091 13.1 0.1 0.17 12.2 0.1 1.4 1 0 0 1 1 1 0 ZU5 domain MFS_1 PF07690.16 ORY08617.1 - 8.9e-13 47.9 21.3 8.9e-13 47.9 21.3 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Sel_put PF04328.13 ORY08617.1 - 0.12 12.4 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Selenoprotein, putative Thioredoxin_16 PF18569.1 ORY08617.1 - 0.15 12.2 0.0 0.27 11.4 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like domain SBP_bac_5 PF00496.22 ORY08618.1 - 2e-08 33.6 0.0 5.6e-05 22.3 0.0 3.0 2 1 1 3 3 3 3 Bacterial extracellular solute-binding proteins, family 5 Middle FGE-sulfatase PF03781.16 ORY08619.1 - 8e-09 35.4 0.0 1.3e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 DUF937 PF06078.11 ORY08619.1 - 0.094 13.3 0.0 0.18 12.4 0.0 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF937) Pkinase PF00069.25 ORY08635.1 - 2.6e-72 243.4 0.0 3.9e-72 242.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY08635.1 - 1e-36 126.6 0.0 2.7e-36 125.2 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY08635.1 - 0.0014 18.0 0.5 1.9 7.7 0.0 2.9 3 0 0 3 3 3 2 Kinase-like Pkinase_fungal PF17667.1 ORY08635.1 - 0.0082 15.0 0.0 0.027 13.3 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase Hist_deacetyl PF00850.19 ORY08636.1 - 7e-83 278.6 0.0 9.6e-83 278.2 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain JAB PF01398.21 ORY08637.1 - 6.8e-28 97.0 0.1 1.3e-27 96.2 0.1 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 ORY08637.1 - 6.9e-13 49.0 0.3 1.1e-12 48.3 0.3 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 ORY08637.1 - 2.6e-07 30.4 0.0 4.6e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Methyltransf_23 PF13489.6 ORY08638.1 - 4.6e-16 59.1 0.0 6.9e-16 58.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY08638.1 - 4.8e-12 46.4 0.0 1.1e-11 45.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY08638.1 - 6.3e-11 42.8 0.0 1.3e-10 41.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY08638.1 - 8e-08 32.2 0.0 2.3e-07 30.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY08638.1 - 1.9e-07 31.7 0.0 5.4e-07 30.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORY08638.1 - 0.0003 20.2 0.0 0.00098 18.5 0.0 1.7 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 ORY08638.1 - 0.0012 18.2 0.0 0.004 16.5 0.0 1.8 3 0 0 3 3 3 1 O-methyltransferase domain PrmA PF06325.13 ORY08638.1 - 0.011 15.2 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 ORY08638.1 - 0.04 13.5 0.0 0.11 12.1 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_16 PF10294.9 ORY08638.1 - 0.041 13.6 0.0 0.063 13.0 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase GidB PF02527.15 ORY08638.1 - 0.1 11.9 0.0 0.27 10.5 0.0 1.7 1 1 0 1 1 1 0 rRNA small subunit methyltransferase G DUF938 PF06080.12 ORY08638.1 - 0.14 11.9 0.0 0.23 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) ABC_membrane PF00664.23 ORY08640.1 - 1.9e-33 116.3 8.3 1.9e-33 116.3 8.3 2.0 2 0 0 2 2 2 1 ABC transporter transmembrane region ABC_tran PF00005.27 ORY08640.1 - 1.2e-31 110.0 0.0 2.7e-31 108.9 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 ORY08640.1 - 2.4e-06 27.2 0.0 9.4e-06 25.2 0.0 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 ORY08640.1 - 0.017 15.4 0.4 0.29 11.4 0.4 2.6 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit RsgA_GTPase PF03193.16 ORY08640.1 - 0.033 14.1 0.0 0.097 12.6 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 ORY08640.1 - 0.081 12.7 0.1 0.28 10.9 0.1 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 ORY08640.1 - 0.26 11.6 0.7 1.2 9.4 0.2 2.4 1 1 1 2 2 2 0 AAA domain WD40 PF00400.32 ORY08641.1 - 8e-10 39.2 9.8 3.4e-06 27.7 0.2 4.3 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY08641.1 - 3.8e-06 27.1 0.0 0.099 13.0 0.0 2.7 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ORY08641.1 - 9e-05 22.4 0.0 0.2 11.5 0.0 2.3 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Zn_ribbon_17 PF17120.5 ORY08641.1 - 0.00023 20.7 8.5 0.00058 19.4 8.5 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-rbx1 PF12678.7 ORY08641.1 - 2.9 8.2 8.9 1.6 9.1 0.4 2.5 2 0 0 2 2 2 0 RING-H2 zinc finger domain Ribosomal_S21e PF01249.18 ORY08642.1 - 2.6e-42 142.8 0.0 2.9e-42 142.7 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e F-box-like PF12937.7 ORY08643.1 - 5.3e-05 23.0 0.1 0.00016 21.5 0.1 1.9 1 0 0 1 1 1 1 F-box-like Glyco_hydro_3 PF00933.21 ORY08644.1 - 4.5e-28 98.5 0.5 1.1e-09 38.2 0.0 3.1 1 1 2 3 3 3 3 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 ORY08644.1 - 4.6e-08 33.3 0.0 5.1e-05 23.3 0.0 2.3 1 1 1 2 2 2 2 Glycosyl hydrolase family 3 C-terminal domain DUF2076 PF09849.9 ORY08645.1 - 0.35 10.9 3.6 0.42 10.6 3.6 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Orn_Arg_deC_N PF02784.16 ORY08645.1 - 0.85 8.9 0.0 0.85 8.9 0.0 1.6 2 0 0 2 2 2 0 Pyridoxal-dependent decarboxylase, pyridoxal binding domain NmrA PF05368.13 ORY08646.1 - 1.1e-44 152.7 0.1 2.1e-42 145.3 0.1 2.1 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ORY08646.1 - 5.2e-11 42.8 0.0 7.6e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 ORY08646.1 - 0.00062 18.9 0.0 0.00091 18.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Sacchrp_dh_NADP PF03435.18 ORY08646.1 - 0.0021 18.3 0.1 0.004 17.4 0.1 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain LicD PF04991.13 ORY08647.1 - 1.3e-20 74.6 6.5 1.1e-13 51.9 2.3 2.3 1 1 1 2 2 2 2 LicD family tRNA-synt_2d PF01409.20 ORY08648.1 - 1.6e-85 286.5 0.0 2.1e-85 286.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD3 PF18553.1 ORY08648.1 - 3.5e-18 65.7 1.8 1.2e-17 64.0 1.8 1.9 1 0 0 1 1 1 1 PheRS DNA binding domain 3 tRNA-synt_2 PF00152.20 ORY08648.1 - 8.5e-07 28.3 0.2 0.00087 18.5 0.0 3.2 3 0 0 3 3 3 2 tRNA synthetases class II (D, K and N) tRNA_synthFbeta PF17759.1 ORY08648.1 - 1.6e-06 27.7 0.0 0.0055 16.2 0.0 2.3 2 0 0 2 2 2 2 Phenylalanyl tRNA synthetase beta chain CLM domain PheRS_DBD2 PF18554.1 ORY08648.1 - 0.00038 20.4 4.1 0.0013 18.7 4.1 2.0 1 0 0 1 1 1 1 PheRS DNA binding domain 2 DUF3405 PF11885.8 ORY08652.1 - 6.8e-202 671.7 18.2 4e-201 669.1 18.2 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF3405) CBM_5_12_2 PF14600.6 ORY08652.1 - 8.3 6.4 7.8 0.73 9.8 2.0 2.2 2 0 0 2 2 2 0 Cellulose-binding domain DUF1460 PF07313.12 ORY08654.1 - 0.11 11.9 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1460) Oxysterol_BP PF01237.18 ORY08657.1 - 1.2e-89 300.7 0.0 7e-88 295.0 0.0 2.1 1 1 0 1 1 1 1 Oxysterol-binding protein Isochorismatase PF00857.20 ORY08658.1 - 6.7e-28 98.0 0.3 3e-27 95.9 0.3 1.8 1 1 0 1 1 1 1 Isochorismatase family COX5B PF01215.19 ORY08659.1 - 1.7e-53 179.7 0.0 2.4e-53 179.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb CTNNB1_binding PF08347.11 ORY08659.1 - 0.013 15.7 0.0 0.017 15.3 0.0 1.2 1 0 0 1 1 1 0 N-terminal CTNNB1 binding Caskin-Pro-rich PF16907.5 ORY08659.1 - 1.9 9.0 7.5 3.6 8.2 2.9 2.2 2 0 0 2 2 2 0 Proline rich region of Caskin proteins CGI-121 PF08617.10 ORY08660.1 - 1.3e-44 152.2 0.0 1.5e-44 152.0 0.0 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 Fungal_trans PF04082.18 ORY08661.1 - 6.6e-10 38.5 0.1 1.3e-09 37.5 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY08661.1 - 5.2e-06 26.5 10.8 8.8e-06 25.8 10.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_S28 PF05577.12 ORY08662.1 - 6.9e-56 189.9 0.9 3.1e-54 184.4 1.8 2.3 2 1 0 2 2 2 2 Serine carboxypeptidase S28 p450 PF00067.22 ORY08667.1 - 1.6e-48 165.6 0.0 2.2e-48 165.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 CbtA PF09490.10 ORY08667.1 - 0.069 12.9 0.1 0.13 12.0 0.1 1.4 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtA) DUF3042 PF11240.8 ORY08667.1 - 0.12 12.4 0.0 0.31 11.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3042) Myb_DNA-bind_6 PF13921.6 ORY08673.1 - 1e-14 54.5 0.1 1.9e-07 31.2 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 ORY08673.1 - 1.9e-11 44.0 0.0 5.4e-05 23.3 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 ORY08673.1 - 0.14 12.4 1.5 3.1 8.1 0.3 2.2 1 1 1 2 2 2 0 SANT/Myb-like domain of DAMP1 Myb_DNA-binding PF00249.31 ORY08676.1 - 2.5e-15 56.4 1.1 1.8e-08 34.4 0.3 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORY08676.1 - 4e-10 39.8 0.5 3.9e-06 27.0 0.1 2.5 2 1 1 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 ORY08676.1 - 0.022 14.6 0.2 0.034 14.0 0.2 1.3 1 0 0 1 1 1 0 Myb DNA-binding like Myb_DNA-bind_6 PF13921.6 ORY08678.1 - 4.5e-05 23.6 0.0 0.0077 16.5 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 ORY08678.1 - 0.00047 20.3 0.9 0.00088 19.4 0.2 1.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain ABC2_membrane PF01061.24 ORY08685.1 - 3.2e-40 137.8 23.3 3.2e-40 137.8 23.3 1.4 2 0 0 2 2 2 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 ORY08685.1 - 8.3e-10 38.3 16.2 8.3e-10 38.3 16.2 2.0 1 1 0 2 2 2 1 ABC-2 family transporter protein ABC2_membrane_2 PF12679.7 ORY08685.1 - 1.8 7.7 19.8 18 4.5 19.8 2.1 1 1 0 1 1 1 0 ABC-2 family transporter protein Tyrosinase PF00264.20 ORY08686.1 - 5.7e-54 183.7 0.0 8.6e-54 183.2 0.0 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase DUF3682 PF12446.8 ORY08686.1 - 0.21 12.1 0.5 0.42 11.1 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) DUF2344 PF10105.9 ORY08688.1 - 0.0093 15.8 0.0 0.013 15.3 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2344) Fungal_trans PF04082.18 ORY08689.1 - 7.2e-05 21.9 0.1 0.00012 21.2 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY08689.1 - 9.6e-05 22.4 13.2 0.00016 21.8 13.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Septin PF00735.18 ORY08690.1 - 1.6e-18 67.0 0.0 1.8e-17 63.6 0.0 2.0 1 1 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 ORY08690.1 - 0.00056 20.0 0.0 0.0018 18.3 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 ORY08690.1 - 0.012 16.0 0.0 0.031 14.6 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain MCM PF00493.23 ORY08690.1 - 0.051 12.7 0.0 0.13 11.3 0.0 1.6 1 0 0 1 1 1 0 MCM P-loop domain NACHT PF05729.12 ORY08690.1 - 0.056 13.4 0.0 0.15 11.9 0.0 1.7 1 0 0 1 1 1 0 NACHT domain Roc PF08477.13 ORY08690.1 - 0.079 13.2 0.0 0.21 11.8 0.0 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 ORY08690.1 - 0.084 13.4 0.0 0.28 11.7 0.0 1.9 2 0 0 2 2 2 0 ABC transporter RsgA_GTPase PF03193.16 ORY08690.1 - 0.14 12.0 0.0 0.47 10.3 0.0 1.8 2 0 0 2 2 2 0 RsgA GTPase AAA_24 PF13479.6 ORY08690.1 - 0.21 11.3 0.0 0.34 10.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain NTF2 PF02136.20 ORY08691.1 - 1.5e-24 86.8 1.1 2.7e-24 86.0 1.1 1.4 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.22 ORY08691.1 - 1.9e-08 34.0 0.0 3.4e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 ORY08691.1 - 0.039 14.0 0.0 0.093 12.8 0.0 1.6 1 0 0 1 1 1 0 RNA binding motif MFS_1 PF07690.16 ORY08692.1 - 1.2e-30 106.7 61.2 2.2e-26 92.6 30.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY08692.1 - 3.7e-06 26.1 34.8 0.0061 15.5 15.7 3.4 2 2 0 2 2 2 2 Sugar (and other) transporter Deltameth_res PF16020.5 ORY08692.1 - 0.46 10.4 4.4 7.7 6.5 0.2 3.3 2 0 0 2 2 2 0 Deltamethrin resistance Methyltransf_31 PF13847.6 ORY08693.1 - 6.5e-28 97.5 0.0 8.5e-28 97.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY08693.1 - 7e-22 78.0 0.0 1.1e-21 77.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY08693.1 - 9.6e-20 71.0 0.0 1.4e-19 70.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY08693.1 - 1.7e-17 63.8 0.0 2.4e-17 63.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY08693.1 - 1.4e-16 61.0 0.0 2.1e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORY08693.1 - 1.7e-10 40.6 0.0 2.4e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 ORY08693.1 - 3.4e-08 33.2 0.0 5.8e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 ORY08693.1 - 5.9e-08 32.4 0.0 1.2e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase PCMT PF01135.19 ORY08693.1 - 0.00012 21.9 0.0 0.00017 21.4 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.20 ORY08693.1 - 0.00022 20.6 0.0 0.0003 20.2 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.6 ORY08693.1 - 0.00022 21.2 0.0 0.00031 20.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 ORY08693.1 - 0.00029 19.9 0.0 0.00041 19.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) PrmA PF06325.13 ORY08693.1 - 0.00046 19.7 0.0 0.0007 19.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_20 PF12147.8 ORY08693.1 - 0.00086 18.5 0.0 0.0011 18.1 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_29 PF03141.16 ORY08693.1 - 0.0011 17.6 0.0 0.0046 15.6 0.0 1.8 1 1 1 2 2 2 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_2 PF00891.18 ORY08693.1 - 0.0014 18.0 0.0 0.0021 17.4 0.0 1.4 1 1 0 1 1 1 1 O-methyltransferase domain Methyltransf_18 PF12847.7 ORY08693.1 - 0.0033 17.4 0.0 0.005 16.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 ORY08693.1 - 0.006 16.2 0.0 0.01 15.4 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW RrnaAD PF00398.20 ORY08693.1 - 0.013 14.5 0.0 0.018 14.1 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase DREV PF05219.12 ORY08693.1 - 0.015 14.4 0.0 0.022 13.9 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase Methyltr_RsmB-F PF01189.17 ORY08693.1 - 0.023 14.3 0.0 0.042 13.5 0.0 1.3 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F Methyltransf_24 PF13578.6 ORY08693.1 - 0.025 15.6 0.0 0.085 13.9 0.0 1.9 1 1 1 2 2 2 0 Methyltransferase domain DUF938 PF06080.12 ORY08693.1 - 0.22 11.3 0.0 0.32 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) MARVEL PF01284.23 ORY08695.1 - 8.7e-20 71.2 4.6 1.1e-19 70.8 4.6 1.1 1 0 0 1 1 1 1 Membrane-associating domain Tetraspanin PF00335.20 ORY08695.1 - 0.26 11.0 4.8 0.14 11.8 3.0 1.4 1 1 0 1 1 1 0 Tetraspanin family DUF2523 PF10734.9 ORY08695.1 - 0.27 11.8 11.1 1.1 9.9 1.5 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2523) YwiC PF14256.6 ORY08695.1 - 2.5 8.4 9.4 1 9.7 6.9 1.6 2 0 0 2 2 2 0 YwiC-like protein MARVEL PF01284.23 ORY08696.1 - 5.9e-28 97.7 7.1 7.1e-28 97.5 7.1 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF2157 PF09925.9 ORY08696.1 - 0.0013 18.6 1.5 0.0025 17.6 0.9 1.8 1 1 0 1 1 1 1 Predicted membrane protein (DUF2157) SseC PF04888.12 ORY08696.1 - 0.12 11.9 1.1 0.13 11.8 1.1 1.2 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family DUF4231 PF14015.6 ORY08696.1 - 0.82 10.2 2.3 23 5.5 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) Peptidase_C50 PF03568.17 ORY08698.1 - 3.9e-148 493.8 0.0 7e-148 493.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase family C50 CHAT PF12770.7 ORY08698.1 - 0.00029 20.3 0.0 0.00093 18.7 0.0 1.8 1 0 0 1 1 1 1 CHAT domain TPR_MalT PF17874.1 ORY08698.1 - 0.011 15.2 0.6 0.011 15.2 0.6 3.3 4 0 0 4 4 4 0 MalT-like TPR region DUF1043 PF06295.12 ORY08699.1 - 0.22 11.5 0.8 2.9 7.9 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) Tropomyosin_1 PF12718.7 ORY08699.1 - 1.1 9.4 3.8 16 5.7 0.1 2.2 2 0 0 2 2 2 0 Tropomyosin like GCD14 PF08704.10 ORY08701.1 - 4e-07 30.0 0.0 4.6e-05 23.2 0.0 2.3 2 0 0 2 2 2 2 tRNA methyltransferase complex GCD14 subunit GCD14_N PF14801.6 ORY08701.1 - 5.4e-06 26.2 0.0 1.1e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit N-term Methyltransf_31 PF13847.6 ORY08701.1 - 0.0002 21.2 0.0 0.082 12.7 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 ORY08701.1 - 0.0023 18.6 0.2 2.6 8.8 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 ORY08701.1 - 0.12 13.1 0.1 2.1 9.0 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Metallophos PF00149.28 ORY08702.1 - 6.8e-19 69.2 1.9 1e-18 68.6 1.9 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 ORY08702.1 - 6.8e-07 29.6 0.0 1.5e-05 25.3 0.0 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Epimerase_2 PF02350.19 ORY08702.1 - 0.018 14.0 0.0 0.028 13.3 0.0 1.2 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase AMP-binding PF00501.28 ORY08703.1 - 5.3e-79 265.8 0.0 6.7e-79 265.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORY08703.1 - 3.9e-15 56.6 0.1 8.1e-15 55.6 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain MazE_antitoxin PF04014.18 ORY08703.1 - 0.066 13.2 0.1 15 5.7 0.1 2.5 2 0 0 2 2 2 0 Antidote-toxin recognition MazE, bacterial antitoxin BTB PF00651.31 ORY08704.1 - 1.3e-05 25.3 0.0 3.4e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Trypan_PARP PF05887.11 ORY08704.1 - 0.0028 17.6 3.1 0.0052 16.8 3.1 1.4 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) SPESP1 PF15754.5 ORY08704.1 - 0.38 9.9 1.3 0.61 9.2 1.3 1.3 1 0 0 1 1 1 0 Sperm equatorial segment protein 1 DUF1989 PF09347.10 ORY08705.1 - 2.8e-28 98.7 0.0 5.5e-18 65.1 0.0 2.9 2 1 0 2 2 2 2 Domain of unknown function (DUF1989) Adipokin_hormo PF06377.11 ORY08706.1 - 0.058 13.7 0.0 1.1e+02 3.3 0.0 3.3 3 0 0 3 3 3 0 Adipokinetic hormone Peptidase_M22 PF00814.25 ORY08709.1 - 3.5e-38 131.8 0.1 4.1e-15 56.2 0.0 4.1 4 0 0 4 4 4 4 Glycoprotease family FGGY_C PF02782.16 ORY08709.1 - 0.04 13.6 0.0 0.093 12.4 0.0 1.6 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain DUF1028 PF06267.12 ORY08709.1 - 0.44 10.3 3.5 0.24 11.2 0.2 2.1 2 1 0 2 2 2 0 Family of unknown function (DUF1028) DUF3336 PF11815.8 ORY08710.1 - 9.9e-52 174.3 2.2 1.5e-51 173.7 2.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 ORY08710.1 - 4e-18 66.3 0.2 2.5e-17 63.8 0.1 2.5 2 1 0 2 2 2 1 Patatin-like phospholipase DUF4337 PF14235.6 ORY08710.1 - 0.24 11.5 0.3 0.49 10.5 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) zf-C2H2 PF00096.26 ORY08711.1 - 1.5e-31 107.1 55.0 7.9e-05 22.9 0.2 10.6 10 0 0 10 10 10 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY08711.1 - 1.6e-19 68.9 53.0 0.027 15.3 0.7 10.5 11 0 0 11 11 10 8 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORY08711.1 - 5.5e-10 39.2 52.5 2.7e-07 30.7 0.8 10.7 12 0 0 12 12 11 3 Zinc-finger double domain zf-H2C2_5 PF13909.6 ORY08711.1 - 1.2e-05 24.9 0.2 1.2e-05 24.9 0.2 8.2 9 0 0 9 9 9 2 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 ORY08711.1 - 0.00014 21.8 14.2 0.0025 17.8 0.5 4.8 5 0 0 5 5 5 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORY08711.1 - 0.00052 20.2 16.4 0.0076 16.5 0.1 6.6 8 0 0 8 8 8 1 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 ORY08711.1 - 0.0051 17.1 37.4 0.46 10.8 2.0 7.8 7 1 1 8 8 8 3 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_aberr PF17017.5 ORY08711.1 - 0.021 15.0 12.9 2 8.5 0.4 5.6 4 2 2 6 6 6 0 Aberrant zinc-finger FOXP-CC PF16159.5 ORY08711.1 - 0.028 15.0 32.1 13 6.5 0.0 8.6 6 2 3 9 9 9 0 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 ORY08711.1 - 0.036 14.4 20.9 0.042 14.1 2.3 5.1 3 2 3 6 6 6 0 C2H2-type zinc ribbon zf-C2H2_3rep PF18868.1 ORY08711.1 - 0.1 13.3 20.2 2.7 8.7 1.5 4.7 2 2 2 4 4 4 0 Zinc finger C2H2-type, 3 repeats zf-met PF12874.7 ORY08711.1 - 0.14 12.6 21.5 2.2 8.8 0.5 7.6 8 1 1 9 9 9 0 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 ORY08711.1 - 2.1 8.1 21.7 0.5 10.2 0.8 5.9 7 0 0 7 7 7 0 zinc-finger C2H2-type RNA_pol_Rpb6 PF01192.22 ORY08712.1 - 1.1e-15 57.2 0.1 2.4e-15 56.2 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb6 Pox_RNA_Pol_19 PF05320.12 ORY08712.1 - 0.0015 18.5 0.1 0.0019 18.2 0.1 1.1 1 0 0 1 1 1 1 Poxvirus DNA-directed RNA polymerase 19 kDa subunit DUF4549 PF15082.6 ORY08712.1 - 0.027 14.2 0.0 0.036 13.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4549) KH_1 PF00013.29 ORY08712.1 - 0.12 12.2 0.6 0.52 10.2 0.2 2.1 2 1 0 2 2 2 0 KH domain Esterase PF00756.20 ORY08713.1 - 8.2e-54 182.9 0.0 9.4e-54 182.7 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Esterase_phd PF10503.9 ORY08713.1 - 1.3e-05 24.8 0.0 0.0011 18.5 0.0 2.1 2 0 0 2 2 2 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 ORY08713.1 - 3.6e-05 23.3 0.1 7.3e-05 22.3 0.1 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Chlorophyllase2 PF12740.7 ORY08713.1 - 0.003 16.5 0.0 0.0051 15.8 0.0 1.3 1 1 0 1 1 1 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 ORY08713.1 - 0.0034 16.7 0.1 0.012 15.0 0.1 1.8 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Lipase_3 PF01764.25 ORY08713.1 - 0.0079 16.1 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.13 ORY08713.1 - 0.017 14.9 0.3 0.059 13.1 0.0 1.8 1 1 1 2 2 2 0 PGAP1-like protein Chlorophyllase PF07224.11 ORY08713.1 - 0.06 12.3 0.0 0.18 10.8 0.0 1.7 2 0 0 2 2 2 0 Chlorophyllase Xpo1 PF08389.12 ORY08714.1 - 9.1e-32 110.2 5.6 1.3e-31 109.7 0.0 4.1 5 1 1 6 6 6 1 Exportin 1-like protein AI-2E_transport PF01594.16 ORY08714.1 - 0.021 14.0 0.3 1.9 7.5 0.1 2.3 2 0 0 2 2 2 0 AI-2E family transporter MAPEG PF01124.18 ORY08715.1 - 2.7e-18 66.1 4.0 3.5e-18 65.7 4.0 1.2 1 0 0 1 1 1 1 MAPEG family PDEase_I PF00233.19 ORY08716.1 - 3e-66 223.5 0.0 4.2e-66 223.1 0.0 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Phosphoesterase PF04185.14 ORY08718.1 - 3.8e-34 118.4 2.1 7.5e-34 117.5 2.0 1.5 1 1 0 1 1 1 1 Phosphoesterase family Sulfatase PF00884.23 ORY08718.1 - 0.00022 20.7 0.5 0.00034 20.1 0.5 1.3 1 0 0 1 1 1 1 Sulfatase Cu-oxidase_3 PF07732.15 ORY08719.1 - 5e-46 155.6 3.3 8.6e-46 154.8 0.6 2.6 2 1 1 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 ORY08719.1 - 9.5e-41 138.7 3.7 1.3e-34 118.9 0.0 3.2 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.22 ORY08719.1 - 3.4e-23 82.5 0.0 5.3e-22 78.6 0.0 2.2 2 0 0 2 2 2 1 Multicopper oxidase SIR2 PF02146.17 ORY08720.1 - 2.4e-31 109.0 0.0 4.5e-31 108.1 0.0 1.5 1 1 0 1 1 1 1 Sir2 family DUF364 PF04016.12 ORY08720.1 - 0.0082 15.7 0.0 0.017 14.7 0.0 1.4 1 0 0 1 1 1 1 Putative heavy-metal chelation DUF2529 PF10740.9 ORY08720.1 - 0.017 14.8 0.0 0.029 14.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2529) TPP_enzyme_M PF00205.22 ORY08720.1 - 0.032 14.0 0.1 0.15 11.8 0.0 2.2 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Myb_DNA-binding PF00249.31 ORY08722.1 - 1.2e-05 25.4 0.4 4.1e-05 23.7 0.1 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORY08722.1 - 4.1e-05 23.7 0.6 0.00047 20.4 0.6 2.4 1 1 0 1 1 1 1 Myb-like DNA-binding domain FAD_binding_4 PF01565.23 ORY08724.1 - 3e-26 91.8 1.1 5.8e-26 90.9 1.1 1.5 1 0 0 1 1 1 1 FAD binding domain Glyco_hydro_3_C PF01915.22 ORY08725.1 - 2.6e-47 161.4 0.0 5.9e-47 160.3 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 ORY08725.1 - 5.9e-41 140.9 0.0 1.3e-40 139.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 ORY08725.1 - 1.6e-22 79.4 0.1 2.9e-22 78.5 0.1 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain ABM PF03992.16 ORY08726.1 - 0.01 16.0 0.0 5.9 7.1 0.0 2.3 2 0 0 2 2 2 0 Antibiotic biosynthesis monooxygenase adh_short PF00106.25 ORY08727.1 - 6.9e-25 87.6 0.0 2.6e-18 66.2 0.0 2.1 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 ORY08727.1 - 2.8e-19 69.6 0.5 4e-12 46.2 0.1 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 ORY08727.1 - 0.017 14.6 0.0 0.027 13.9 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 ORY08727.1 - 0.071 12.1 0.0 0.097 11.7 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family YjeF_N PF03853.15 ORY08727.1 - 0.074 12.9 0.1 0.12 12.2 0.1 1.3 1 0 0 1 1 1 0 YjeF-related protein N-terminus KR PF08659.10 ORY08727.1 - 0.19 11.7 1.0 0.76 9.7 1.0 1.9 1 1 0 1 1 1 0 KR domain GFO_IDH_MocA PF01408.22 ORY08732.1 - 1.2e-20 74.5 0.1 2e-20 73.8 0.1 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.24 ORY08732.1 - 0.00071 20.0 0.0 0.009 16.5 0.0 2.4 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain RSN1_7TM PF02714.15 ORY08733.1 - 7.1e-71 238.7 16.8 1.1e-70 238.0 16.8 1.3 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 ORY08733.1 - 3.1e-38 131.0 1.9 3.1e-38 131.0 1.9 2.0 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 ORY08733.1 - 2.2e-37 129.0 0.0 3.3e-37 128.4 0.0 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter Methyltransf_23 PF13489.6 ORY08734.1 - 6.9e-11 42.3 0.0 1.2e-10 41.5 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY08734.1 - 1.3e-08 35.5 0.0 2.1e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY08734.1 - 1.6e-06 28.0 0.0 1.8e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY08734.1 - 2.4e-05 25.0 0.0 4.2e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY08734.1 - 0.00016 22.3 0.0 0.00028 21.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ORY08734.1 - 0.0037 16.8 0.0 0.0083 15.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 ORY08734.1 - 0.0074 15.8 0.0 0.033 13.7 0.0 2.2 1 1 1 2 2 2 1 Putative methyltransferase Ubie_methyltran PF01209.18 ORY08734.1 - 0.031 13.6 0.0 0.13 11.5 0.0 1.9 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family Glyco_hydro_61 PF03443.14 ORY08736.1 - 8.6e-58 195.7 0.3 1.1e-57 195.3 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CNP1 PF08750.11 ORY08736.1 - 0.057 13.4 0.0 0.19 11.7 0.0 1.8 2 0 0 2 2 2 0 CNP1-like family DUF2271 PF10029.9 ORY08736.1 - 0.082 12.5 0.9 0.12 12.1 0.1 1.6 2 0 0 2 2 2 0 Predicted periplasmic protein (DUF2271) Nnf1 PF03980.14 ORY08737.1 - 3.3e-26 91.8 0.9 6.4e-26 90.9 0.9 1.5 1 0 0 1 1 1 1 Nnf1 Baculo_PEP_C PF04513.12 ORY08737.1 - 0.0023 18.0 0.8 0.061 13.4 0.6 2.1 2 0 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1840 PF08895.11 ORY08737.1 - 0.005 17.2 0.9 0.019 15.3 0.2 2.2 1 1 0 2 2 2 1 Domain of unknown function (DUF1840) ATG16 PF08614.11 ORY08737.1 - 0.0091 16.2 2.5 0.012 15.9 2.5 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) BshC PF10079.9 ORY08737.1 - 0.012 14.4 0.4 2.1 7.0 0.5 2.0 2 0 0 2 2 2 0 Bacillithiol biosynthesis BshC PhaC_N PF07167.13 ORY08737.1 - 0.076 12.7 0.4 1 9.0 0.1 2.3 2 1 0 2 2 2 0 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus GAS PF13851.6 ORY08737.1 - 0.093 12.1 1.6 0.13 11.6 0.3 1.7 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding ABC_tran_CTD PF16326.5 ORY08737.1 - 0.23 11.7 7.4 0.19 12.0 1.8 2.9 2 1 1 3 3 3 0 ABC transporter C-terminal domain Cytochrom_B562 PF07361.11 ORY08737.1 - 0.26 12.0 2.1 2.2 9.0 0.4 2.2 2 0 0 2 2 2 0 Cytochrome b562 Snapin_Pallidin PF14712.6 ORY08737.1 - 0.57 10.6 3.4 1.6 9.2 0.7 2.6 2 2 1 3 3 3 0 Snapin/Pallidin F-box-like PF12937.7 ORY08739.1 - 0.0036 17.2 1.0 0.21 11.5 0.3 2.7 2 0 0 2 2 2 2 F-box-like F-box PF00646.33 ORY08739.1 - 0.68 9.9 2.5 1.5 8.8 0.1 2.7 3 0 0 3 3 3 0 F-box domain DUF2706 PF10913.8 ORY08740.1 - 0.11 12.4 0.1 0.38 10.6 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2706) DUF4834 PF16118.5 ORY08741.1 - 0.014 16.4 0.0 0.041 14.8 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DUF2615 PF11027.8 ORY08741.1 - 0.016 15.3 0.2 0.066 13.4 0.2 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2615) DUF3357 PF11837.8 ORY08741.1 - 0.039 14.4 0.0 0.18 12.3 0.0 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) DUF997 PF06196.12 ORY08741.1 - 0.087 12.8 0.1 0.16 12.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF997) PorA PF11271.8 ORY08741.1 - 0.26 10.6 1.1 0.88 8.8 0.1 2.2 3 0 0 3 3 3 0 Porin PorA EGF_2 PF07974.13 ORY08741.1 - 1.5 9.3 8.5 3.2 8.2 8.5 1.5 1 0 0 1 1 1 0 EGF-like domain DUF4863 PF16155.5 ORY08742.1 - 8.2e-66 220.6 0.0 9.6e-66 220.4 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4863) Exonuc_VII_S PF02609.16 ORY08742.1 - 0.016 15.2 0.0 0.05 13.7 0.0 1.7 2 0 0 2 2 2 0 Exonuclease VII small subunit LCIB_C_CA PF18599.1 ORY08742.1 - 0.078 12.3 0.2 0.11 11.7 0.2 1.2 1 0 0 1 1 1 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases Prok-JAB PF14464.6 ORY08742.1 - 0.15 11.8 0.0 0.22 11.3 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic homologs of the JAB domain PBP PF01161.20 ORY08743.1 - 6.3e-09 36.2 0.0 7.3e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Glyco_hydro_16 PF00722.21 ORY08744.1 - 1.2e-09 37.9 0.0 5.8e-09 35.7 0.0 2.0 1 1 1 2 2 2 1 Glycosyl hydrolases family 16 tRNA_SAD PF07973.14 ORY08745.1 - 1.3e-08 34.8 1.9 2.1e-08 34.1 0.5 2.1 2 0 0 2 2 2 1 Threonyl and Alanyl tRNA synthetase second additional domain tRNA-synt_2c PF01411.19 ORY08745.1 - 0.068 11.7 0.0 0.093 11.2 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class II (A) NIF3 PF01784.18 ORY08746.1 - 7e-07 29.1 0.0 9.4e-07 28.7 0.0 1.1 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) zf-RING_UBOX PF13445.6 ORY08747.1 - 3.7e-06 26.8 11.3 3.7e-06 26.8 11.3 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 ORY08747.1 - 3.8e-05 23.9 10.8 3.8e-05 23.9 10.8 2.7 3 1 1 4 4 4 1 Ring finger domain zf-C3HC4 PF00097.25 ORY08747.1 - 0.00028 20.7 8.3 0.00028 20.7 8.3 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORY08747.1 - 0.00029 20.7 12.9 0.00042 20.2 11.2 2.2 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 ORY08747.1 - 0.00064 19.8 11.4 0.01 16.0 11.4 2.6 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 ORY08747.1 - 0.0029 17.4 17.0 0.16 11.9 8.1 3.4 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) Chromo PF00385.24 ORY08747.1 - 0.019 14.9 1.6 0.023 14.6 0.2 1.8 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain TFIIIC_sub6 PF10419.9 ORY08747.1 - 0.093 12.6 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 TFIIIC subunit triple barrel domain zf-RING_10 PF16685.5 ORY08747.1 - 0.57 10.4 10.1 0.46 10.7 4.7 2.4 2 0 0 2 2 2 0 zinc RING finger of MSL2 Prok-RING_4 PF14447.6 ORY08747.1 - 2.3 8.2 20.8 0.069 13.0 7.6 3.0 3 1 0 3 3 3 0 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 ORY08747.1 - 3 7.8 21.5 0.96 9.4 13.8 2.9 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) F-box-like PF12937.7 ORY08748.1 - 1.7e-09 37.4 0.8 4.5e-09 36.1 0.8 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY08748.1 - 0.0001 22.1 1.6 0.00028 20.7 1.6 1.8 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 ORY08748.1 - 0.074 12.9 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 F-box Acetyltransf_10 PF13673.7 ORY08749.1 - 1.5e-09 37.8 0.0 2.2e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ORY08749.1 - 7.4e-09 35.9 0.0 1e-08 35.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORY08749.1 - 6.8e-08 32.7 0.0 1.1e-07 32.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 ORY08749.1 - 3.6e-06 27.1 0.0 5.1e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ORY08749.1 - 1.3e-05 25.1 0.0 2.1e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 ORY08749.1 - 0.024 14.8 0.0 0.042 14.0 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase GNAT_acetyltr_2 PF13718.6 ORY08749.1 - 0.053 12.9 0.0 0.078 12.4 0.0 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase 2 DUF1275 PF06912.11 ORY08750.1 - 0.11 12.4 1.9 0.66 9.9 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1275) Vps62 PF06101.11 ORY08751.1 - 1e-11 43.9 6.1 1.3e-10 40.3 6.1 2.2 1 1 0 1 1 1 1 Vacuolar protein sorting-associated protein 62 INSIG PF07281.12 ORY08752.1 - 0.47 10.1 1.5 5.3 6.6 0.0 2.2 2 0 0 2 2 2 0 Insulin-induced protein (INSIG) MFS_1 PF07690.16 ORY08753.1 - 2.1e-26 92.7 24.9 6.4e-26 91.1 23.9 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY08753.1 - 4.9e-09 35.6 8.3 4.9e-09 35.6 8.3 1.7 2 1 0 2 2 2 1 Sugar (and other) transporter Cation_ATPase_N PF00690.26 ORY08753.1 - 0.027 14.2 0.0 0.073 12.8 0.0 1.8 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus MscS_TM PF12794.7 ORY08753.1 - 0.034 13.0 1.1 0.082 11.8 0.5 1.8 1 1 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Glt_symporter PF03616.14 ORY08753.1 - 0.055 12.1 0.4 0.1 11.3 0.4 1.3 1 0 0 1 1 1 0 Sodium/glutamate symporter 7TM_GPCR_Srw PF10324.9 ORY08753.1 - 0.084 12.1 0.2 0.2 10.9 0.0 1.7 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srw AA_permease PF00324.21 ORY08767.1 - 1.3e-103 347.2 37.4 1.6e-103 346.9 37.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ORY08767.1 - 8.1e-29 100.7 39.5 1e-28 100.4 39.5 1.0 1 0 0 1 1 1 1 Amino acid permease zf-MYND PF01753.18 ORY08768.1 - 8.5e-09 35.4 17.5 1.2e-08 34.9 17.5 1.2 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 ORY08768.1 - 0.037 14.3 9.5 0.074 13.4 9.5 1.4 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Anti-TRAP PF15777.5 ORY08768.1 - 0.5 10.4 7.6 1.1 9.3 7.6 1.6 1 0 0 1 1 1 0 Tryptophan RNA-binding attenuator protein inhibitory protein GATase_4 PF13230.6 ORY08772.1 - 9.2e-11 41.1 0.1 4.9e-10 38.8 0.0 1.9 2 0 0 2 2 2 1 Glutamine amidotransferases class-II GATase_6 PF13522.6 ORY08772.1 - 9.1e-08 32.4 0.0 1.6e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain MFS_1 PF07690.16 ORY08773.1 - 6.7e-33 114.1 34.4 4.3e-32 111.4 29.9 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY08773.1 - 1.7e-10 40.4 10.1 1.7e-10 40.4 10.1 2.9 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 ORY08773.1 - 0.082 11.3 10.1 0.0069 14.9 5.3 1.5 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) Wzy_C PF04932.15 ORY08773.1 - 0.39 10.3 0.0 0.39 10.3 0.0 3.1 4 1 0 4 4 4 0 O-Antigen ligase PhyH PF05721.13 ORY08774.1 - 1.6e-21 77.6 0.0 2.1e-21 77.2 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) FAD_binding_3 PF01494.19 ORY08775.1 - 1.1e-23 84.1 0.1 6.2e-23 81.6 0.1 1.9 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 ORY08775.1 - 1.6e-11 44.4 9.9 4.4e-06 26.5 0.1 2.7 2 1 1 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ORY08775.1 - 1.1e-10 41.2 0.1 0.00032 20.0 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ORY08775.1 - 1.9e-07 30.5 2.0 3.5e-07 29.7 0.8 1.8 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 ORY08775.1 - 2e-07 30.1 0.3 2.6e-05 23.1 0.2 2.0 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox PF00070.27 ORY08775.1 - 1.6e-06 28.6 0.6 0.01 16.4 0.2 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 ORY08775.1 - 1.7e-05 24.3 2.7 0.0088 15.4 0.0 2.6 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 ORY08775.1 - 5.7e-05 22.7 4.8 0.00014 21.4 4.8 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 ORY08775.1 - 6.4e-05 22.2 0.2 0.00021 20.5 0.4 1.6 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 ORY08775.1 - 0.00011 22.4 3.6 0.00019 21.6 2.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 ORY08775.1 - 0.0019 17.1 1.3 0.27 10.1 0.2 2.2 2 0 0 2 2 2 2 Tryptophan halogenase Thi4 PF01946.17 ORY08775.1 - 0.009 15.3 0.5 0.014 14.6 0.5 1.2 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 ORY08775.1 - 0.012 14.9 0.0 0.024 13.9 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 ORY08775.1 - 0.012 14.7 0.0 0.04 13.0 0.0 1.7 2 0 0 2 2 2 0 Squalene epoxidase Lycopene_cycl PF05834.12 ORY08775.1 - 0.012 14.7 1.7 0.034 13.2 1.7 1.7 1 1 0 1 1 1 0 Lycopene cyclase protein 3HCDH_N PF02737.18 ORY08775.1 - 0.019 14.8 0.1 0.039 13.8 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 ORY08775.1 - 0.058 12.7 0.7 0.17 11.2 0.2 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain MCRA PF06100.11 ORY08775.1 - 0.15 10.8 0.2 6 5.5 0.3 2.2 2 0 0 2 2 2 0 MCRA family Trp_DMAT PF11991.8 ORY08776.1 - 1e-08 35.1 0.0 1.1e-08 34.9 0.0 1.0 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase Sugar_tr PF00083.24 ORY08779.1 - 1.5e-35 122.9 27.8 1.4e-26 93.4 6.6 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 ORY08779.1 - 1e-21 77.3 33.9 2.9e-21 75.8 30.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Cnl2_NKP2 PF09447.10 ORY08779.1 - 0.19 11.9 0.5 0.44 10.7 0.5 1.5 1 0 0 1 1 1 0 Cnl2/NKP2 family protein THRAP3_BCLAF1 PF15440.6 ORY08780.1 - 4.8 6.1 7.9 6.8 5.6 7.9 1.1 1 0 0 1 1 1 0 THRAP3/BCLAF1 family p450 PF00067.22 ORY08781.1 - 2.1e-29 102.6 0.1 5.4e-22 78.2 0.1 3.0 2 1 0 2 2 2 2 Cytochrome P450 HET PF06985.11 ORY08782.1 - 2.5e-25 89.5 0.3 4.3e-25 88.8 0.3 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) NAD_binding_10 PF13460.6 ORY08783.1 - 3.6e-12 46.5 0.0 7.4e-12 45.5 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 ORY08783.1 - 0.0024 17.5 0.0 0.0042 16.7 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family F-box-like PF12937.7 ORY08784.1 - 0.0068 16.3 1.1 0.031 14.2 1.0 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 ORY08784.1 - 0.016 15.1 2.2 0.021 14.7 0.5 2.1 2 0 0 2 2 2 0 F-box domain Spo7 PF03907.13 ORY08785.1 - 3.8e-88 294.7 0.0 4.6e-88 294.4 0.0 1.1 1 0 0 1 1 1 1 Spo7-like protein BPD_transp_2 PF02653.16 ORY08785.1 - 0.083 12.0 0.3 0.11 11.7 0.3 1.2 1 0 0 1 1 1 0 Branched-chain amino acid transport system / permease component Abhydrolase_1 PF00561.20 ORY08786.1 - 2.2e-22 79.9 0.0 2.6e-21 76.4 0.0 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ORY08786.1 - 1.3e-15 57.3 0.0 5.2e-15 55.4 0.0 1.8 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ORY08786.1 - 2.7e-15 57.6 0.4 6.1e-14 53.1 0.4 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.11 ORY08786.1 - 3e-05 23.5 0.0 6.7e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Esterase PF00756.20 ORY08786.1 - 0.00027 20.7 0.0 0.0006 19.5 0.0 1.6 1 0 0 1 1 1 1 Putative esterase Chlorophyllase2 PF12740.7 ORY08786.1 - 0.0087 15.0 0.0 0.013 14.4 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Thioesterase PF00975.20 ORY08786.1 - 0.015 15.4 1.0 0.27 11.3 1.1 2.5 1 1 0 1 1 1 0 Thioesterase domain PGAP1 PF07819.13 ORY08786.1 - 0.14 11.8 0.0 0.83 9.3 0.0 1.9 2 0 0 2 2 2 0 PGAP1-like protein Chlorophyllase PF07224.11 ORY08786.1 - 0.19 10.7 0.0 0.29 10.1 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase CorA PF01544.18 ORY08787.1 - 0.00061 19.2 0.4 0.00061 19.2 0.4 1.5 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein HisKA PF00512.25 ORY08787.1 - 0.033 14.2 0.0 6.7 6.8 0.0 2.6 2 0 0 2 2 2 0 His Kinase A (phospho-acceptor) domain Ank_4 PF13637.6 ORY08788.1 - 7.8e-06 26.3 0.0 0.00081 19.9 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 ORY08788.1 - 7.4e-05 23.3 0.1 0.76 10.4 0.0 2.9 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 ORY08788.1 - 0.0002 21.7 0.1 0.84 10.2 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat DUF1859 PF08948.10 ORY08788.1 - 0.02 14.8 0.1 4 7.4 0.0 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF1859) Ank_3 PF13606.6 ORY08788.1 - 0.13 12.9 0.1 12 6.9 0.0 3.6 4 0 0 4 4 4 0 Ankyrin repeat MFS_1 PF07690.16 ORY08789.1 - 3.6e-20 72.2 37.3 3.6e-20 72.2 37.3 2.3 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 ORY08789.1 - 8.3e-13 47.6 23.2 2.2e-12 46.2 12.3 2.0 1 1 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 ORY08791.1 - 5e-41 141.0 22.0 2.3e-40 138.9 22.0 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY08791.1 - 4.7e-33 114.6 43.4 4.4e-30 104.8 27.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily GMC_oxred_N PF00732.19 ORY08792.1 - 6.5e-23 81.5 0.0 1.9e-12 47.2 0.0 2.2 1 1 0 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.13 ORY08792.1 - 5.4e-06 27.0 0.0 9.7e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Sulfate_transp PF00916.20 ORY08793.1 - 2.9e-81 273.1 7.4 4.2e-81 272.6 7.4 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 ORY08793.1 - 6.6e-17 61.2 0.0 1.1e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 ORY08793.1 - 0.00011 22.5 0.0 0.00031 21.0 0.0 1.9 1 1 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 ORY08793.1 - 2.8 8.4 14.7 0.58 10.6 5.2 2.7 2 1 0 2 2 2 0 Molybdate transporter of MFS superfamily AlaDh_PNT_N PF05222.15 ORY08794.1 - 2.8e-28 98.9 0.0 4.4e-28 98.3 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.21 ORY08794.1 - 0.0015 17.9 0.0 0.0023 17.2 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 ORY08795.1 - 6.1e-58 197.1 0.2 7.4e-58 196.8 0.2 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ORY08795.1 - 0.00038 20.6 0.9 0.00092 19.4 0.9 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 ORY08795.1 - 0.029 14.9 0.4 0.058 14.0 0.4 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 ORY08795.1 - 0.063 13.5 0.3 0.12 12.6 0.3 1.4 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox_2 PF07992.14 ORY08795.1 - 0.077 12.2 0.1 0.13 11.4 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MIF4G PF02854.19 ORY08796.1 - 3.8e-63 213.0 0.3 2.2e-33 115.7 0.0 3.4 3 0 0 3 3 3 3 MIF4G domain Upf2 PF04050.14 ORY08796.1 - 5.4e-42 143.7 6.3 5.4e-42 143.7 6.3 3.2 3 0 0 3 3 3 1 Up-frameshift suppressor 2 Chitin_synth_2 PF03142.15 ORY08798.1 - 8.8e-24 84.0 2.5 8.8e-24 84.0 2.5 3.0 3 0 0 3 3 3 2 Chitin synthase Glyco_trans_2_3 PF13632.6 ORY08798.1 - 1.8e-14 54.1 1.6 1.8e-14 54.1 1.6 2.3 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 ORY08798.1 - 5.4e-10 39.5 0.0 1.4e-09 38.2 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 ORY08798.1 - 0.002 18.0 0.1 0.6 9.9 0.1 2.6 2 0 0 2 2 2 2 Glycosyl transferase family 2 SKN1 PF03935.15 ORY08799.1 - 4e-220 731.4 4.1 4.7e-220 731.2 4.1 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) TIR-like PF10137.9 ORY08799.1 - 0.03 14.3 0.0 0.06 13.3 0.0 1.4 1 0 0 1 1 1 0 Predicted nucleotide-binding protein containing TIR-like domain Sof1 PF04158.14 ORY08799.1 - 0.13 12.6 0.0 0.2 12.0 0.0 1.2 1 0 0 1 1 1 0 Sof1-like domain TPK_catalytic PF04263.16 ORY08800.1 - 5.2e-31 107.2 0.0 7.7e-31 106.6 0.0 1.2 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 ORY08800.1 - 3.5e-16 58.7 0.1 6e-16 57.9 0.1 1.4 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain Zn_clus PF00172.18 ORY08804.1 - 0.0031 17.6 9.4 0.0051 16.9 9.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ORY08806.1 - 4.2e-15 55.5 0.1 8e-15 54.6 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY08807.1 - 3.3e-09 36.7 9.9 4.8e-09 36.2 9.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 ORY08808.1 - 4.8e-09 35.6 26.9 3.7e-08 32.7 26.9 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 ORY08808.1 - 0.00031 19.2 1.9 0.00043 18.7 0.9 1.7 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.24 ORY08808.1 - 0.012 14.5 18.7 1.1 8.0 18.7 2.9 1 1 0 1 1 1 0 Sugar (and other) transporter p450 PF00067.22 ORY08809.1 - 9.7e-54 182.8 0.0 1.3e-53 182.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_S15 PF02129.18 ORY08810.1 - 9.4e-28 97.5 6.9 1.2e-24 87.3 0.1 2.2 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 ORY08810.1 - 4.6e-09 36.6 0.1 9.8e-08 32.2 0.0 2.2 1 1 0 2 2 2 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain DUF1479 PF07350.12 ORY08811.1 - 7.5e-07 28.3 0.0 0.13 10.9 0.0 3.0 3 0 0 3 3 3 3 Protein of unknown function (DUF1479) PhyH PF05721.13 ORY08811.1 - 0.0006 20.1 2.6 0.0048 17.2 2.6 2.0 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Fasciclin PF02469.22 ORY08812.1 - 1.8e-34 118.7 0.1 3.6e-19 69.2 0.0 2.4 2 0 0 2 2 2 2 Fasciclin domain F-box-like PF12937.7 ORY08814.1 - 5.4e-09 35.8 0.8 9.2e-08 31.9 0.0 2.9 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 ORY08814.1 - 0.052 13.4 2.4 0.12 12.3 0.1 2.7 2 0 0 2 2 2 0 F-box domain LRR_6 PF13516.6 ORY08814.1 - 0.12 12.5 0.3 5.6 7.3 0.1 3.3 3 0 0 3 3 3 0 Leucine Rich repeat PAS_3 PF08447.12 ORY08824.1 - 1.4e-16 60.5 1.8 1.1e-15 57.7 1.3 2.4 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 ORY08824.1 - 1.8e-10 41.0 0.0 0.0002 21.6 0.0 3.3 3 0 0 3 3 3 2 PAS domain PAS_4 PF08448.10 ORY08824.1 - 0.00014 22.1 0.1 0.29 11.4 0.1 3.2 3 0 0 3 3 3 2 PAS fold PAS PF00989.25 ORY08824.1 - 0.00049 20.1 0.0 0.094 12.7 0.0 3.0 3 0 0 3 3 3 1 PAS fold Yos1 PF08571.10 ORY08825.1 - 1.5e-33 114.8 0.5 1.7e-33 114.7 0.5 1.0 1 0 0 1 1 1 1 Yos1-like ATP1G1_PLM_MAT8 PF02038.16 ORY08825.1 - 0.16 11.4 0.5 0.3 10.6 0.5 1.4 1 0 0 1 1 1 0 ATP1G1/PLM/MAT8 family UCH PF00443.29 ORY08826.1 - 1.1e-56 192.1 0.0 1.1e-56 192.1 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 ORY08826.1 - 5e-27 95.3 0.8 1.3e-20 74.2 0.1 2.5 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 ORY08826.1 - 0.017 14.6 0.8 0.017 14.6 0.8 2.8 3 0 0 3 3 3 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase HrpA_pilin PF09589.10 ORY08826.1 - 4.4 8.1 7.0 1.6 9.5 3.1 2.1 2 0 0 2 2 2 0 HrpA pilus formation protein DUF4407 PF14362.6 ORY08826.1 - 6.2 6.1 9.6 11 5.2 9.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Amino_oxidase PF01593.24 ORY08827.1 - 2.6e-88 297.3 0.1 2.6e-87 294.0 0.1 2.1 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase SWIRM PF04433.17 ORY08827.1 - 1.2e-15 57.6 0.1 2.3e-15 56.7 0.1 1.5 1 0 0 1 1 1 1 SWIRM domain NAD_binding_8 PF13450.6 ORY08827.1 - 4.2e-07 30.1 0.1 1.3e-06 28.5 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HMG_box PF00505.19 ORY08827.1 - 9.6e-05 22.7 1.4 0.00077 19.8 0.1 2.6 1 1 1 2 2 2 1 HMG (high mobility group) box DAO PF01266.24 ORY08827.1 - 0.00015 21.5 0.0 0.0018 17.9 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ORY08827.1 - 0.0011 18.3 0.1 0.008 15.4 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ORY08827.1 - 0.025 14.6 0.0 1.7 8.6 0.1 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding Spo0A_C PF08769.11 ORY08827.1 - 0.093 12.8 0.1 16 5.7 0.0 2.5 2 0 0 2 2 2 0 Sporulation initiation factor Spo0A C terminal SNase PF00565.17 ORY08828.1 - 1.9e-25 89.4 0.3 3.2e-25 88.7 0.3 1.3 1 0 0 1 1 1 1 Staphylococcal nuclease homologue CPSase_L_D2 PF02786.17 ORY08829.1 - 7.4e-105 349.1 0.0 7.6e-81 270.6 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 ORY08829.1 - 1.2e-41 141.9 0.1 2.8e-41 140.7 0.1 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp PF02222.22 ORY08829.1 - 1e-17 64.2 0.0 4.2e-09 36.2 0.0 2.7 3 0 0 3 3 3 2 ATP-grasp domain Dala_Dala_lig_C PF07478.13 ORY08829.1 - 6.6e-17 61.7 0.2 7.2e-09 35.5 0.1 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 ORY08829.1 - 3.9e-10 39.6 0.0 0.0008 19.2 0.0 2.7 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon RimK PF08443.11 ORY08829.1 - 1.8e-05 24.4 0.0 0.0047 16.6 0.0 2.5 2 0 0 2 2 2 2 RimK-like ATP-grasp domain ATP-grasp_5 PF13549.6 ORY08829.1 - 5.4e-05 22.7 0.1 0.058 12.8 0.0 3.0 3 0 0 3 3 3 2 ATP-grasp domain GARS_A PF01071.19 ORY08829.1 - 0.00018 21.4 0.1 0.12 12.1 0.0 2.6 2 0 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Epimerase PF01370.21 ORY08829.1 - 0.12 11.9 0.0 0.56 9.6 0.0 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Scm3 PF10384.9 ORY08830.1 - 4.5e-14 51.9 0.7 9.6e-14 50.9 0.1 1.9 2 0 0 2 2 2 1 Centromere protein Scm3 Trypan_PARP PF05887.11 ORY08830.1 - 6.1e-06 26.2 52.1 6.1e-06 26.2 52.1 4.9 3 1 1 5 5 5 2 Procyclic acidic repetitive protein (PARP) zf-C2H2 PF00096.26 ORY08830.1 - 7.6e-05 23.0 0.3 0.00015 22.0 0.3 1.5 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY08830.1 - 0.002 18.8 0.1 0.0043 17.8 0.1 1.5 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORY08830.1 - 0.033 14.5 0.0 0.057 13.7 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding APG6 PF04111.12 ORY08831.1 - 2.7e-69 232.7 0.0 3.9e-69 232.2 0.0 1.2 1 0 0 1 1 1 1 Apg6 BARA domain APG6_N PF17675.1 ORY08831.1 - 1.2e-33 116.5 8.3 1.2e-33 116.5 8.3 1.7 2 0 0 2 2 2 1 Apg6 coiled-coil region DUF4164 PF13747.6 ORY08831.1 - 0.011 16.0 8.1 0.022 15.0 8.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) NuA4 PF09340.10 ORY08831.1 - 0.036 13.9 0.2 0.079 12.8 0.2 1.6 1 0 0 1 1 1 0 Histone acetyltransferase subunit NuA4 zf-C4H2 PF10146.9 ORY08831.1 - 0.039 14.3 0.1 0.039 14.3 0.1 1.9 2 0 0 2 2 2 0 Zinc finger-containing protein Jnk-SapK_ap_N PF09744.9 ORY08831.1 - 0.076 13.2 6.3 0.18 12.0 6.3 1.6 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 DUF4407 PF14362.6 ORY08831.1 - 0.66 9.3 5.3 1 8.6 5.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4140 PF13600.6 ORY08831.1 - 0.69 10.4 8.8 4.1 7.9 4.9 2.9 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) FUSC PF04632.12 ORY08831.1 - 4.7 5.6 8.4 7.6 4.9 8.4 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family PNP_UDP_1 PF01048.20 ORY08832.1 - 4.3e-05 22.9 0.0 7.2e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Phosphorylase superfamily CorA PF01544.18 ORY08833.1 - 6.9e-07 28.9 9.6 6.9e-07 28.9 9.6 1.7 2 1 0 2 2 2 1 CorA-like Mg2+ transporter protein Cation_efflux PF01545.21 ORY08833.1 - 0.044 13.5 0.1 0.081 12.6 0.1 1.3 1 0 0 1 1 1 0 Cation efflux family Ank_4 PF13637.6 ORY08834.1 - 9.2e-11 42.1 0.4 0.57 10.8 0.0 4.8 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 ORY08834.1 - 2.2e-05 24.9 0.0 0.0016 19.0 0.0 3.2 2 1 1 3 3 3 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ORY08834.1 - 0.00023 21.4 0.1 5.5 7.4 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeats (many copies) DUF4298 PF14131.6 ORY08834.1 - 0.37 10.8 2.4 20 5.2 0.0 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4298) B2-adapt-app_C PF09066.10 ORY08834.1 - 0.41 10.8 3.1 0.47 10.5 1.4 1.9 2 0 0 2 2 2 0 Beta2-adaptin appendage, C-terminal sub-domain HET PF06985.11 ORY08835.1 - 1.6e-11 44.8 0.0 1.6e-11 44.8 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) APH PF01636.23 ORY08836.1 - 1.6e-08 34.8 0.0 6.9e-08 32.7 0.0 2.0 2 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 ORY08836.1 - 0.0017 18.0 0.1 0.0044 16.6 0.1 1.6 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.11 ORY08836.1 - 0.09 11.6 0.0 0.19 10.6 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) HEPN_SAV_6107 PF18726.1 ORY08838.1 - 0.1 13.1 0.1 0.16 12.5 0.1 1.2 1 0 0 1 1 1 0 SAV_6107-like HEPN F-box-like PF12937.7 ORY08839.1 - 0.021 14.7 0.0 0.27 11.2 0.0 3.0 4 1 0 4 4 4 0 F-box-like F-box PF00646.33 ORY08839.1 - 0.2 11.6 1.2 2.5 8.1 0.1 2.9 2 0 0 2 2 2 0 F-box domain FMN_red PF03358.15 ORY08840.1 - 2.5e-08 33.8 0.0 3.1e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_1 PF00258.25 ORY08840.1 - 2.6e-05 24.5 0.3 0.00037 20.7 0.3 2.3 1 1 0 1 1 1 1 Flavodoxin Flavodoxin_2 PF02525.17 ORY08840.1 - 0.00012 21.9 0.0 0.00015 21.5 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_5 PF12724.7 ORY08840.1 - 0.21 11.8 0.0 2.7 8.2 0.0 2.0 1 1 0 2 2 2 0 Flavodoxin domain HpcH_HpaI PF03328.14 ORY08841.1 - 2e-44 151.4 0.0 2.8e-44 150.9 0.0 1.2 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 ORY08841.1 - 2.3e-14 53.3 0.0 1.9e-06 27.3 0.0 2.1 2 0 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold DUF846 PF05832.12 ORY08842.1 - 1.5e-48 164.4 10.8 1.8e-48 164.1 10.8 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) TMEM220 PF15071.6 ORY08842.1 - 0.096 13.5 0.6 0.096 13.5 0.6 1.9 2 0 0 2 2 2 0 Transmembrane family 220, helix DUF4191 PF13829.6 ORY08842.1 - 1.6 8.0 3.9 1.9 7.7 0.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) Oxidored_q4 PF00507.19 ORY08843.1 - 0.018 15.2 0.0 0.026 14.7 0.0 1.3 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 2-Hacid_dh_C PF02826.19 ORY08845.1 - 1.1e-45 155.2 0.2 1.3e-29 102.8 0.0 2.4 3 0 0 3 3 3 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain XdhC_C PF13478.6 ORY08845.1 - 0.0071 16.8 0.0 0.015 15.8 0.0 1.6 1 1 0 1 1 1 1 XdhC Rossmann domain NAD_binding_2 PF03446.15 ORY08845.1 - 0.0088 16.2 0.0 0.017 15.3 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh PF00389.30 ORY08845.1 - 0.029 14.0 0.0 0.038 13.7 0.0 1.1 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain IlvN PF07991.12 ORY08845.1 - 0.033 13.8 0.0 0.062 12.9 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain 3HCDH_N PF02737.18 ORY08845.1 - 0.038 13.9 0.0 0.078 12.9 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 ORY08845.1 - 0.1 11.9 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Gp_dh_N PF00044.24 ORY08845.1 - 0.12 12.8 0.1 0.29 11.5 0.1 1.7 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 7tm_2 PF00002.24 ORY08847.1 - 1.2e-06 28.0 10.3 1.2e-06 28.0 10.3 1.7 1 1 1 2 2 2 1 7 transmembrane receptor (Secretin family) Pox_A14 PF05767.12 ORY08847.1 - 0.86 9.8 5.8 26 5.1 0.3 3.7 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 Glyco_hydro_16 PF00722.21 ORY08850.1 - 2.8e-07 30.2 0.1 5.7e-07 29.2 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 ANAPC_CDC26 PF10471.9 ORY08851.1 - 1e-12 48.7 3.8 1.2e-12 48.4 3.8 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex APC subunit CDC26 ThiF PF00899.21 ORY08853.1 - 3.1e-61 206.9 0.0 4.2e-61 206.4 0.0 1.2 1 0 0 1 1 1 1 ThiF family E2_bind PF08825.10 ORY08853.1 - 1.4e-31 108.5 0.3 2.1e-31 107.9 0.3 1.3 1 0 0 1 1 1 1 E2 binding domain E1_UFD PF09358.10 ORY08853.1 - 0.0093 16.6 0.0 0.024 15.4 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin fold domain Ecm33 PF12454.8 ORY08853.1 - 0.087 13.0 0.8 0.19 11.9 0.8 1.5 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein Shikimate_DH PF01488.20 ORY08853.1 - 0.23 11.5 0.2 0.89 9.6 0.0 1.9 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase UBA_e1_thiolCys PF10585.9 ORY08853.1 - 0.3 11.0 2.3 6.3 6.6 0.0 2.4 2 0 0 2 2 2 0 Ubiquitin-activating enzyme active site Telomere_reg-2 PF10193.9 ORY08854.1 - 6.1e-35 120.0 0.0 8.7e-34 116.3 0.0 2.8 3 0 0 3 3 3 1 Telomere length regulation protein Serglycin PF04360.12 ORY08854.1 - 0.09 12.7 0.2 0.18 11.8 0.2 1.4 1 0 0 1 1 1 0 Serglycin WLM PF08325.10 ORY08855.1 - 1.9e-56 191.2 0.7 2.8e-56 190.6 0.7 1.3 1 0 0 1 1 1 1 WLM domain DZR PF12773.7 ORY08855.1 - 1.1e-05 25.3 0.0 3e-05 23.9 0.0 1.7 1 1 0 1 1 1 1 Double zinc ribbon zf-RanBP PF00641.18 ORY08855.1 - 0.0092 15.3 1.5 0.0092 15.3 1.5 3.2 3 0 0 3 3 3 1 Zn-finger in Ran binding protein and others DUF1776 PF08643.10 ORY08856.1 - 2.3e-87 293.1 0.0 2.9e-87 292.8 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) adh_short PF00106.25 ORY08856.1 - 0.00029 20.3 0.0 0.00067 19.2 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY08856.1 - 0.034 13.7 0.0 0.15 11.6 0.0 1.8 1 1 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase CAP_N PF01213.19 ORY08856.1 - 0.11 12.0 0.1 0.16 11.4 0.1 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Sel1 PF08238.12 ORY08857.1 - 2e-09 37.8 17.3 0.0017 19.0 0.7 3.8 4 0 0 4 4 4 3 Sel1 repeat tRNA_synthFbeta PF17759.1 ORY08857.1 - 0.2 11.0 0.0 0.35 10.3 0.0 1.3 1 0 0 1 1 1 0 Phenylalanyl tRNA synthetase beta chain CLM domain TLP1_add_C PF18313.1 ORY08858.1 - 3.6e-24 84.5 0.0 9.1e-24 83.2 0.0 1.8 1 0 0 1 1 1 1 Thiolase-like protein type 1 additional C-terminal domain Pro-kuma_activ PF09286.11 ORY08859.1 - 9.7e-43 145.9 1.0 4.4e-41 140.5 0.9 2.3 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 ORY08859.1 - 3.4e-08 33.1 0.7 5.5e-08 32.4 0.7 1.3 1 0 0 1 1 1 1 Subtilase family DUF3659 PF12396.8 ORY08862.1 - 4.8e-290 936.0 175.7 6e-25 86.9 2.3 14.7 14 0 0 14 14 14 14 Protein of unknown function (DUF3659) DUF2167 PF09935.9 ORY08862.1 - 0.63 9.2 7.5 0.062 12.5 0.6 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2167) Phage_fiber_C PF06820.12 ORY08862.1 - 1.7 9.1 6.2 38 4.7 0.0 5.3 6 0 0 6 6 6 0 Putative prophage tail fibre C-terminus p450 PF00067.22 ORY08864.1 - 9.4e-94 314.7 0.0 1.1e-93 314.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3267 PF11667.8 ORY08866.1 - 5.5 7.3 6.8 1.5 9.1 0.5 2.8 3 0 0 3 3 3 0 Putative zincin peptidase tRNA-synt_2 PF00152.20 ORY08867.1 - 2.1e-72 243.8 0.0 3.6e-72 243.1 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.9 ORY08867.1 - 5.7e-13 48.5 0.0 8.2e-13 48.0 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2156) tRNA_anti-codon PF01336.25 ORY08867.1 - 7.4e-06 25.9 0.1 1.6e-05 24.8 0.1 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 ORY08867.1 - 0.015 14.8 0.1 6.7 6.1 0.1 2.4 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) Nuc_N PF14448.6 ORY08867.1 - 0.14 12.0 0.1 0.49 10.3 0.1 1.9 2 0 0 2 2 2 0 Nuclease N terminal HAUS6_N PF14661.6 ORY08867.1 - 0.47 10.0 3.3 0.91 9.1 3.3 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DUF3395 PF11875.8 ORY08867.1 - 8.5 6.2 8.1 16 5.4 8.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3395) Questin_oxidase PF14027.6 ORY08868.1 - 5.2e-98 328.7 0.2 6.3e-98 328.5 0.2 1.1 1 0 0 1 1 1 1 Questin oxidase-like Tubulin PF00091.25 ORY08869.1 - 3.4e-65 219.9 0.0 4.6e-65 219.5 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 ORY08869.1 - 8e-44 148.8 0.0 1.2e-43 148.2 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 ORY08869.1 - 0.0008 19.1 0.0 0.0014 18.3 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain MS_channel PF00924.18 ORY08870.1 - 3.2e-26 92.2 0.9 5.5e-26 91.4 0.9 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_5 PF13202.6 ORY08870.1 - 5e-05 22.6 0.0 0.00015 21.1 0.0 1.9 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.32 ORY08870.1 - 0.00046 19.6 0.3 0.0012 18.2 0.3 1.8 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 ORY08870.1 - 0.00067 19.4 0.0 0.0035 17.2 0.0 2.3 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 ORY08870.1 - 0.005 17.3 0.3 0.014 15.8 0.3 1.7 1 0 0 1 1 1 1 EF-hand domain pair Pho88 PF10032.9 ORY08870.1 - 0.76 9.0 2.8 0.77 9.0 0.2 2.1 2 0 0 2 2 2 0 Phosphate transport (Pho88) Ferlin_C PF16165.5 ORY08870.1 - 0.78 9.7 2.7 0.52 10.2 0.1 2.1 2 0 0 2 2 2 0 Ferlin C-terminus DUF3671 PF12420.8 ORY08870.1 - 0.82 9.8 4.7 4.5 7.4 0.2 2.9 2 1 0 2 2 2 0 Protein of unknown function SMP PF04927.12 ORY08872.1 - 5.7e-05 23.5 9.7 0.0017 18.8 0.3 3.2 4 0 0 4 4 4 2 Seed maturation protein LRR_6 PF13516.6 ORY08873.1 - 4.2e-13 48.2 5.1 0.015 15.3 0.0 7.2 7 0 0 7 7 7 3 Leucine Rich repeat LRR_4 PF12799.7 ORY08873.1 - 2.7e-08 34.0 4.1 0.47 11.0 0.0 5.5 6 0 0 6 6 6 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY08873.1 - 0.003 17.9 2.0 1.1e+02 3.9 0.0 5.6 7 0 0 7 7 7 0 Leucine Rich Repeat LRR_8 PF13855.6 ORY08873.1 - 0.0049 16.6 9.4 2.2 8.1 0.0 4.8 4 1 0 4 4 4 2 Leucine rich repeat Radial_spoke PF04712.12 ORY08873.1 - 1.4 7.8 0.0 1.4 7.8 0.0 2.2 2 0 0 2 2 2 0 Radial spokehead-like protein SDA1 PF05285.12 ORY08873.1 - 1.7 8.0 22.7 2.5 7.4 22.7 1.2 1 0 0 1 1 1 0 SDA1 COX17 PF05051.13 ORY08874.1 - 1.5e-21 76.4 7.6 1.8e-21 76.2 7.6 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.10 ORY08874.1 - 0.00087 19.3 4.4 0.026 14.5 0.1 2.1 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like UPF0203 PF05254.12 ORY08874.1 - 0.48 10.7 6.4 0.95 9.8 6.4 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) Alg6_Alg8 PF03155.15 ORY08875.1 - 1.2e-125 420.2 24.8 4.1e-80 270.1 11.0 2.3 2 1 0 2 2 2 2 ALG6, ALG8 glycosyltransferase family MDD_C PF18376.1 ORY08892.1 - 6.7e-41 140.1 0.0 1.2e-40 139.3 0.0 1.4 1 1 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 ORY08892.1 - 7.8e-07 29.2 0.2 1.5e-06 28.3 0.2 1.4 1 0 0 1 1 1 1 GHMP kinases N terminal domain DUF1977 PF09320.11 ORY08893.1 - 4.2e-08 33.4 0.0 4.4e-08 33.3 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) DnaJ PF00226.31 ORY08894.1 - 8.3e-06 25.8 0.2 3.9e-05 23.7 0.1 2.1 1 1 1 2 2 2 1 DnaJ domain Aim19 PF10315.9 ORY08896.1 - 6.4e-05 23.2 0.1 7.7e-05 23.0 0.1 1.3 1 0 0 1 1 1 1 Altered inheritance of mitochondria protein 19 DUF1977 PF09320.11 ORY08897.1 - 1.2e-27 96.2 0.1 2.1e-27 95.4 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) DnaJ PF00226.31 ORY08897.1 - 8e-20 70.7 0.0 1.4e-19 69.9 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain MDD_C PF18376.1 ORY08898.1 - 3.1e-65 219.4 0.0 4.1e-65 219.0 0.0 1.2 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 ORY08898.1 - 3.2e-09 36.9 1.0 8.9e-09 35.5 1.0 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain Cyto_heme_lyase PF01265.17 ORY08899.1 - 6.2e-41 140.9 16.5 7.2e-38 130.8 2.9 2.9 1 1 1 2 2 2 2 Cytochrome c/c1 heme lyase SOG2 PF10428.9 ORY08899.1 - 2.5 7.2 11.6 3 6.9 11.6 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Pneumo_att_G PF05539.11 ORY08899.1 - 3.6 7.1 10.6 4.7 6.7 10.6 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G BTB PF00651.31 ORY08900.1 - 0.0004 20.6 0.0 0.00087 19.5 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Beta_helix PF13229.6 ORY08901.1 - 0.016 15.1 22.1 0.086 12.7 0.4 2.3 1 1 1 2 2 2 0 Right handed beta helix region TIG PF01833.24 ORY08901.1 - 0.096 12.8 5.5 0.37 10.9 3.3 2.6 2 0 0 2 2 2 0 IPT/TIG domain Coat_X PF07552.11 ORY08901.1 - 5.6 6.9 5.6 8.3 6.3 0.1 3.4 4 0 0 4 4 4 0 Spore Coat Protein X and V domain Ank_4 PF13637.6 ORY08902.1 - 4.7e-09 36.6 0.1 0.0015 19.1 0.0 4.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 ORY08902.1 - 6.5e-07 29.9 0.2 5.3e-05 23.7 0.1 3.2 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ORY08902.1 - 7.7e-07 29.3 0.2 5e-06 26.7 0.1 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY08902.1 - 3.4e-05 23.9 0.0 2.9 8.7 0.0 5.8 5 1 1 6 6 6 1 Ankyrin repeat AT_hook PF02178.19 ORY08902.1 - 0.092 12.7 0.8 0.24 11.4 0.8 1.8 1 0 0 1 1 1 0 AT hook motif BTB PF00651.31 ORY08903.1 - 2.4e-06 27.7 0.0 5.1e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain CAP_N PF01213.19 ORY08904.1 - 4.6 6.6 8.6 6.3 6.2 8.6 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal RGS PF00615.19 ORY08910.1 - 1.8e-31 108.9 0.3 5.5e-31 107.3 0.1 2.0 2 0 0 2 2 2 1 Regulator of G protein signaling domain DEP PF00610.21 ORY08910.1 - 2.9e-23 81.7 0.0 4.1e-17 62.0 0.0 3.5 3 0 0 3 3 3 3 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DUF1304 PF06993.12 ORY08910.1 - 0.023 14.7 0.0 0.051 13.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1304) Pkinase PF00069.25 ORY08911.1 - 4.7e-60 203.2 0.0 6e-60 202.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY08911.1 - 2e-29 102.7 0.0 2.9e-29 102.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY08911.1 - 2.2e-09 37.1 0.0 3e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 ORY08911.1 - 0.021 14.2 0.0 0.045 13.1 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Flavoprotein PF02441.19 ORY08912.1 - 9.7e-44 148.9 0.0 2.9e-43 147.4 0.0 1.6 1 1 0 1 1 1 1 Flavoprotein HET PF06985.11 ORY08913.1 - 6.1e-05 23.4 0.0 0.002 18.5 0.0 2.4 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Aldo_ket_red PF00248.21 ORY08914.1 - 7.5e-75 251.9 0.0 8.5e-75 251.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF2158 PF09926.9 ORY08914.1 - 0.12 12.1 0.0 0.32 10.7 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized small protein (DUF2158) Pkinase PF00069.25 ORY08915.1 - 6.1e-62 209.4 0.0 8.4e-62 208.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY08915.1 - 7.3e-36 123.8 0.0 9.7e-36 123.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY08915.1 - 2.2e-07 30.5 0.0 1.5e-06 27.8 0.0 1.8 1 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 ORY08915.1 - 0.004 16.5 0.1 0.0081 15.5 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 ORY08915.1 - 0.014 14.2 0.0 0.024 13.4 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase FTA2 PF13095.6 ORY08915.1 - 0.022 14.4 0.0 0.28 10.8 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Nop14 PF04147.12 ORY08916.1 - 0.14 10.4 2.4 0.54 8.4 1.5 1.9 2 0 0 2 2 2 0 Nop14-like family NOA36 PF06524.12 ORY08916.1 - 2.5 7.4 8.8 4.1 6.6 8.8 1.2 1 0 0 1 1 1 0 NOA36 protein AIM5 PF17050.5 ORY08917.1 - 1.9e-20 73.4 0.5 2.6e-20 73.0 0.5 1.2 1 0 0 1 1 1 1 Altered inheritance of mitochondria 5 LacI PF00356.21 ORY08917.1 - 0.0064 16.2 0.0 1.3 8.9 0.0 2.3 2 0 0 2 2 2 2 Bacterial regulatory proteins, lacI family CRCB PF02537.15 ORY08917.1 - 0.081 13.2 0.6 0.11 12.8 0.6 1.2 1 0 0 1 1 1 0 CrcB-like protein, Camphor Resistance (CrcB) Pollen_allerg_1 PF01357.21 ORY08918.1 - 2.1e-10 40.5 0.0 5.4e-10 39.1 0.0 1.6 1 0 0 1 1 1 1 Pollen allergen CBM_1 PF00734.18 ORY08918.1 - 2.7e-10 40.0 7.6 2.7e-10 40.0 7.6 3.8 4 0 0 4 4 4 1 Fungal cellulose binding domain DPBB_1 PF03330.18 ORY08918.1 - 5.7e-05 23.3 0.0 0.00016 21.9 0.0 1.8 1 0 0 1 1 1 1 Lytic transglycolase PPR_2 PF13041.6 ORY08919.1 - 3.8e-24 84.6 0.8 2.7e-11 43.5 0.0 4.1 4 0 0 4 4 4 2 PPR repeat family PPR_3 PF13812.6 ORY08919.1 - 6e-16 58.3 0.9 5.6e-07 29.5 0.0 4.2 3 1 1 4 4 4 3 Pentatricopeptide repeat domain PPR_1 PF12854.7 ORY08919.1 - 4.8e-09 35.8 0.0 0.0031 17.2 0.0 4.5 5 0 0 5 5 5 2 PPR repeat PPR PF01535.20 ORY08919.1 - 4.2e-07 29.8 3.6 0.0013 18.9 0.0 5.3 5 0 0 5 5 5 1 PPR repeat PPR_long PF17177.4 ORY08919.1 - 3.5e-05 23.3 0.2 0.17 11.2 0.0 2.6 3 0 0 3 3 3 2 Pentacotripeptide-repeat region of PRORP MRP-S27 PF10037.9 ORY08919.1 - 0.0072 15.2 0.1 0.012 14.5 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S27 DUF5457 PF17540.2 ORY08919.1 - 0.86 9.7 3.9 1.8 8.7 3.9 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5457) cwf18 PF08315.12 ORY08920.1 - 5.8e-37 127.4 7.2 5.8e-37 127.4 7.2 1.9 2 0 0 2 2 2 1 cwf18 pre-mRNA splicing factor zf-CCHC_3 PF13917.6 ORY08921.1 - 6.9e-18 64.3 5.7 2.1e-17 62.8 5.7 1.9 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 ORY08921.1 - 0.12 12.5 2.6 0.21 11.7 2.6 1.4 1 0 0 1 1 1 0 Zinc knuckle SUZ PF12752.7 ORY08922.1 - 5.2e-16 59.1 2.3 5.2e-16 59.1 2.3 3.9 4 1 0 4 4 4 1 SUZ domain R3H PF01424.22 ORY08922.1 - 8e-08 32.2 0.0 1.7e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 R3H domain Oxidored_q6 PF01058.22 ORY08924.1 - 4.6e-22 78.2 0.0 6.8e-22 77.7 0.0 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Arrestin_N PF00339.29 ORY08924.1 - 0.21 11.6 0.0 0.31 11.1 0.0 1.2 1 0 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain Sedlin_N PF04628.13 ORY08925.1 - 1.9e-14 53.9 0.0 4.8e-14 52.6 0.0 1.6 1 1 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 ORY08925.1 - 0.11 12.5 0.1 1.8 8.5 0.1 2.1 1 1 0 1 1 1 0 Sybindin-like family AFG1_ATPase PF03969.16 ORY08926.1 - 1.5e-58 198.4 0.1 7.2e-28 97.5 0.0 5.0 5 0 0 5 5 5 4 AFG1-like ATPase AAA_5 PF07728.14 ORY08926.1 - 9.1e-05 22.5 0.0 0.00018 21.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 ORY08926.1 - 0.00015 22.2 0.9 0.036 14.5 0.0 3.0 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 ORY08926.1 - 0.0029 17.9 0.0 0.009 16.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 ORY08926.1 - 0.042 14.3 0.0 0.09 13.2 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 ORY08926.1 - 0.068 12.9 0.0 0.2 11.4 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 ORY08926.1 - 0.076 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region NACHT PF05729.12 ORY08926.1 - 0.13 12.2 0.0 0.28 11.1 0.0 1.6 1 0 0 1 1 1 0 NACHT domain Filament_head PF04732.14 ORY08926.1 - 3.2 8.7 5.2 57 4.7 0.2 3.0 2 1 0 2 2 2 0 Intermediate filament head (DNA binding) region Ribosomal_L31e PF01198.19 ORY08927.1 - 1.9e-30 104.9 0.4 3.6e-30 104.0 0.4 1.4 1 0 0 1 1 1 1 Ribosomal protein L31e zinc_ribbon_6 PF14599.6 ORY08927.1 - 8.5e-25 86.5 1.9 8.5e-25 86.5 1.9 4.0 3 1 0 3 3 3 1 Zinc-ribbon zf-CHY PF05495.12 ORY08927.1 - 5.8e-19 68.3 20.8 5.8e-19 68.3 20.8 3.4 3 0 0 3 3 3 2 CHY zinc finger zf-RING_2 PF13639.6 ORY08927.1 - 3.2e-07 30.6 6.6 3.2e-07 30.6 6.6 4.7 3 1 2 5 5 5 1 Ring finger domain zf-RING_5 PF14634.6 ORY08927.1 - 5.4e-06 26.3 4.4 5.4e-06 26.3 4.4 5.2 4 1 2 6 6 6 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 ORY08927.1 - 1.2e-05 25.0 4.8 1.2e-05 25.0 4.8 4.2 5 1 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORY08927.1 - 0.00014 21.8 2.8 0.00014 21.8 2.8 2.8 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 ORY08927.1 - 0.00053 19.8 6.4 0.00053 19.8 6.4 4.8 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 ORY08927.1 - 0.0045 16.7 1.2 0.0045 16.7 1.2 3.6 4 0 0 4 4 4 1 RING-like zinc finger Muraidase PF11860.8 ORY08927.1 - 0.031 14.5 0.0 0.062 13.5 0.0 1.4 1 0 0 1 1 1 0 N-acetylmuramidase Lectin_N PF03954.14 ORY08928.1 - 0.15 11.8 5.8 0.27 11.0 5.8 1.4 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain BRE1 PF08647.11 ORY08928.1 - 0.54 10.4 24.8 0.057 13.5 18.7 2.2 1 1 2 3 3 3 0 BRE1 E3 ubiquitin ligase DUF2031 PF09592.10 ORY08928.1 - 0.81 9.2 15.7 1.3 8.5 15.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2031) DUF4407 PF14362.6 ORY08928.1 - 6 6.1 10.7 7.7 5.8 10.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) zf-H2C2_2 PF13465.6 ORY08931.1 - 0.1 13.1 15.0 8.9 6.9 0.4 3.8 3 1 0 3 3 3 0 Zinc-finger double domain zf-C2H2 PF00096.26 ORY08931.1 - 0.19 12.2 0.5 0.19 12.2 0.5 3.9 3 1 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY08931.1 - 7.5 7.7 18.7 2.1 9.4 0.3 4.1 3 1 0 3 3 3 0 C2H2-type zinc finger TAP35_44 PF07265.11 ORY08932.1 - 0.042 13.9 0.0 0.063 13.3 0.0 1.3 1 0 0 1 1 1 0 Tapetum specific protein TAP35/TAP44 DIE2_ALG10 PF04922.12 ORY08933.1 - 1.4e-124 416.4 4.7 1.7e-124 416.1 4.7 1.1 1 0 0 1 1 1 1 DIE2/ALG10 family Sld5 PF05916.11 ORY08934.1 - 7.5e-32 110.0 0.0 1.2e-31 109.4 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein ArgoL1 PF08699.10 ORY08936.1 - 0.11 12.2 0.2 0.25 11.1 0.1 1.7 2 0 0 2 2 2 0 Argonaute linker 1 domain RasGEF PF00617.19 ORY08939.1 - 4.5e-52 176.8 0.2 8e-52 176.0 0.2 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 ORY08939.1 - 5.7e-14 52.2 0.0 2.8e-13 50.0 0.0 2.3 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_9 PF14604.6 ORY08939.1 - 9.9e-05 22.1 0.0 0.00024 20.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 ORY08939.1 - 0.00022 20.8 0.0 0.00056 19.5 0.0 1.7 1 0 0 1 1 1 1 SH3 domain Abhydrolase_6 PF12697.7 ORY08942.1 - 0.00074 20.2 1.8 0.00074 20.2 1.8 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ORY08942.1 - 0.01 15.5 0.0 0.062 12.9 0.0 2.0 1 1 1 2 2 2 0 alpha/beta hydrolase fold LysE PF01810.18 ORY08942.1 - 0.046 13.2 0.4 0.078 12.4 0.4 1.3 1 0 0 1 1 1 0 LysE type translocator Melibiase_2 PF16499.5 ORY08943.1 - 3.9e-58 196.9 2.7 5e-56 190.0 2.7 2.2 1 1 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 ORY08943.1 - 2.5e-10 40.3 0.2 4.2e-09 36.3 0.0 2.6 2 0 0 2 2 2 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 ORY08943.1 - 2.4e-07 30.0 0.0 4.6e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Melibiase Fungal_trans PF04082.18 ORY08944.1 - 7.7e-13 48.1 0.0 1.5e-12 47.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sugar_tr PF00083.24 ORY08945.1 - 1.4e-83 281.3 26.6 1.6e-83 281.1 26.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY08945.1 - 2.3e-17 63.0 32.4 2.3e-17 63.0 32.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily p450 PF00067.22 ORY08946.1 - 9.2e-69 232.4 0.0 1.1e-68 232.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Sugar_tr PF00083.24 ORY08947.1 - 1.6e-86 291.0 29.9 1.8e-86 290.8 29.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY08947.1 - 9.4e-16 57.7 36.5 1.5e-11 43.9 12.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.18 ORY08948.1 - 6.2e-27 94.3 2.4 9.1e-27 93.7 2.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY08948.1 - 7.8e-08 32.3 6.8 2e-07 31.0 6.8 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Chorismate_synt PF01264.21 ORY08949.1 - 4.9e-136 452.7 0.0 5.6e-136 452.6 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase CRAL_TRIO_2 PF13716.6 ORY08950.1 - 8.1e-37 126.5 0.0 1.3e-36 125.8 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain RhoGAP PF00620.27 ORY08950.1 - 6e-20 71.6 0.0 1.3e-19 70.5 0.0 1.6 1 1 0 1 1 1 1 RhoGAP domain CRAL_TRIO PF00650.20 ORY08950.1 - 2.2e-05 24.2 0.0 5.4e-05 23.0 0.0 1.5 2 0 0 2 2 2 1 CRAL/TRIO domain Tcf25 PF04910.14 ORY08952.1 - 4e-81 272.8 0.1 5.3e-81 272.4 0.1 1.1 1 0 0 1 1 1 1 Transcriptional repressor TCF25 SPT6_acidic PF14632.6 ORY08952.1 - 0.0037 17.8 2.2 0.0037 17.8 2.2 2.1 3 0 0 3 3 3 1 Acidic N-terminal SPT6 PP2C PF00481.21 ORY08953.1 - 1.7e-38 132.7 0.0 2.8e-38 132.0 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 ORY08953.1 - 7.8e-05 22.4 0.1 0.00015 21.5 0.1 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 ORY08953.1 - 0.026 14.5 0.0 0.93 9.4 0.0 2.7 3 0 0 3 3 3 0 Stage II sporulation protein E (SpoIIE) Glyco_hydro_61 PF03443.14 ORY08955.1 - 6.1e-48 163.5 0.0 9.8e-48 162.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Pex19 PF04614.12 ORY08957.1 - 1.4e-75 254.3 13.1 1.9e-75 253.8 13.1 1.2 1 0 0 1 1 1 1 Pex19 protein family Amidohydro_3 PF07969.11 ORY08957.1 - 0.034 13.6 1.1 0.048 13.1 1.1 1.2 1 0 0 1 1 1 0 Amidohydrolase family ATP19 PF11022.8 ORY08957.1 - 0.53 10.7 2.5 2.6 8.5 2.5 2.2 1 1 0 1 1 1 0 ATP synthase subunit K DEC-1_N PF04625.13 ORY08957.1 - 0.6 9.1 10.6 1.1 8.2 9.7 1.6 1 1 1 2 2 2 0 DEC-1 protein, N-terminal region CAP_N PF01213.19 ORY08957.1 - 0.67 9.4 5.3 3.8 6.9 1.5 2.5 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal FliE PF02049.18 ORY08957.1 - 1 9.5 11.7 0.85 9.8 7.2 3.1 2 1 1 3 3 3 0 Flagellar hook-basal body complex protein FliE GET2 PF08690.10 ORY08957.1 - 2.4 7.8 12.1 0.32 10.6 7.2 2.0 1 1 2 3 3 3 0 GET complex subunit GET2 DUF2514 PF10721.9 ORY08957.1 - 4.4 7.3 9.1 0.33 11.0 3.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2514) UQ_con PF00179.26 ORY08958.1 - 6.8e-49 165.1 0.0 7.7e-49 165.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 ORY08958.1 - 0.00024 20.8 0.0 0.0003 20.5 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 ORY08958.1 - 0.016 15.5 1.5 0.042 14.1 1.5 1.7 1 1 0 1 1 1 0 RWD domain RRM_1 PF00076.22 ORY08959.1 - 1.3e-07 31.3 0.0 2.2e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) V_ATPase_I PF01496.19 ORY08959.1 - 0.047 11.6 2.2 0.051 11.5 2.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ZapB PF06005.12 ORY08959.1 - 0.06 13.8 5.3 0.06 13.8 5.3 1.7 2 0 0 2 2 2 0 Cell division protein ZapB EMP24_GP25L PF01105.24 ORY08959.1 - 0.07 13.1 2.2 0.088 12.7 2.2 1.1 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD TPD52 PF04201.15 ORY08959.1 - 0.077 12.6 4.0 0.093 12.3 4.0 1.1 1 0 0 1 1 1 0 Tumour protein D52 family DUF3450 PF11932.8 ORY08959.1 - 0.14 11.4 5.6 0.17 11.2 5.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF724 PF05266.14 ORY08959.1 - 0.16 11.8 6.5 0.19 11.5 6.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Spc7 PF08317.11 ORY08959.1 - 0.28 10.0 5.4 0.33 9.8 5.4 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein MerR-DNA-bind PF09278.11 ORY08959.1 - 0.32 11.5 4.6 0.63 10.6 4.6 1.4 1 0 0 1 1 1 0 MerR, DNA binding DivIC PF04977.15 ORY08959.1 - 0.6 9.9 4.3 0.94 9.3 4.3 1.3 1 0 0 1 1 1 0 Septum formation initiator adh_short PF00106.25 ORY08960.1 - 3e-19 69.3 0.2 1.3e-16 60.6 0.2 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 ORY08960.1 - 2.3e-08 33.9 0.4 2.7e-07 30.4 0.2 2.1 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY08960.1 - 4.5e-05 23.5 0.7 6.7e-05 22.9 0.1 1.6 2 0 0 2 2 2 1 KR domain Di19_C PF14571.6 ORY08961.1 - 0.52 10.9 4.9 0.49 11.0 1.5 2.7 1 1 1 2 2 2 0 Stress-induced protein Di19, C-terminal DUF3439 PF11921.8 ORY08961.1 - 3.8 7.5 11.7 9 6.3 11.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Helo_like_N PF17111.5 ORY08962.1 - 2.5e-06 27.0 8.0 1.5e-05 24.5 0.5 3.2 1 1 2 3 3 3 1 Fungal N-terminal domain of STAND proteins mTERF PF02536.14 ORY08962.1 - 0.037 13.0 0.7 0.062 12.2 0.7 1.3 1 0 0 1 1 1 0 mTERF Glycos_transf_1 PF00534.20 ORY08962.1 - 0.052 13.1 0.0 0.12 11.9 0.0 1.7 1 0 0 1 1 1 0 Glycosyl transferases group 1 FUSC PF04632.12 ORY08962.1 - 0.15 10.6 0.3 0.25 9.8 0.3 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF948 PF06103.11 ORY08962.1 - 0.16 12.3 6.6 0.45 10.8 0.1 3.7 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) YlbD_coat PF14071.6 ORY08962.1 - 0.27 11.5 5.8 1.2 9.4 0.6 3.3 3 1 0 3 3 3 0 Putative coat protein HET PF06985.11 ORY08964.1 - 9.5e-33 113.6 0.0 5.2e-32 111.2 0.0 2.1 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF3458_C PF17432.2 ORY08966.1 - 0.094 12.1 0.1 0.17 11.3 0.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3458_C) ARM repeats Med11 PF10280.9 ORY08966.1 - 0.13 12.7 0.4 0.18 12.3 0.4 1.3 1 0 0 1 1 1 0 Mediator complex protein AMP-binding PF00501.28 ORY08980.1 - 1.6e-68 231.2 0.0 2.1e-68 230.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORY08980.1 - 2.1e-14 54.2 0.9 4.7e-14 53.1 0.9 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain FAD_binding_8 PF08022.12 ORY08981.1 - 0.032 14.3 0.0 0.061 13.4 0.0 1.4 1 0 0 1 1 1 0 FAD-binding domain SLATT_1 PF18181.1 ORY08981.1 - 6.1 6.8 6.8 1.2 9.1 1.4 2.3 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 DHDPS PF00701.22 ORY08982.1 - 1.2e-37 129.2 0.0 1.6e-37 128.8 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family GST_N PF02798.20 ORY08983.1 - 1.9e-14 53.8 0.0 4.1e-14 52.7 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 ORY08983.1 - 1.2e-13 51.3 0.0 2e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 ORY08983.1 - 1.1e-11 44.8 0.0 2.3e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 ORY08983.1 - 1.5e-08 34.6 0.1 2.9e-08 33.6 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 ORY08983.1 - 2.7e-08 34.0 0.0 4.4e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 ORY08983.1 - 8.9e-06 25.8 0.0 1.7e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Peptidase_S24 PF00717.23 ORY08983.1 - 0.0025 17.7 0.0 0.0049 16.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase S24-like GST_N_4 PF17172.4 ORY08983.1 - 0.045 14.5 0.0 0.086 13.6 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain Glutaredoxin2_C PF04399.13 ORY08983.1 - 0.13 12.1 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain Zn_clus PF00172.18 ORY08984.1 - 2.6e-07 30.6 12.1 4.7e-07 29.8 12.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NAD_binding_10 PF13460.6 ORY08985.1 - 1.1e-33 116.7 0.1 1.3e-33 116.4 0.1 1.1 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 ORY08985.1 - 6.7e-05 22.6 0.0 0.00015 21.4 0.0 1.6 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 ORY08985.1 - 0.00018 21.0 0.0 0.00089 18.8 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family HTH_53 PF18606.1 ORY08985.1 - 0.14 11.8 0.0 0.54 10.0 0.0 1.9 2 0 0 2 2 2 0 Zap helix turn helix N-terminal domain Ank_2 PF12796.7 ORY08986.1 - 1.2e-08 35.4 0.2 1.8e-08 34.9 0.2 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ORY08986.1 - 1.7e-06 27.9 0.7 1.3 9.8 0.0 3.2 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 ORY08986.1 - 2.2e-06 28.1 0.9 0.12 13.0 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 ORY08986.1 - 2.5e-05 24.5 1.2 2.1 8.7 0.1 3.2 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 ORY08986.1 - 7.2e-05 23.1 3.8 0.37 11.3 0.1 3.3 2 1 1 3 3 3 2 Ankyrin repeat UDPG_MGDP_dh_C PF03720.15 ORY08986.1 - 0.078 13.4 0.0 0.31 11.5 0.0 1.8 1 1 1 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain ADH_N PF08240.12 ORY08987.1 - 2.1e-25 88.7 1.3 5.7e-25 87.3 1.3 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORY08987.1 - 7.1e-19 68.1 0.5 1.4e-18 67.1 0.5 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 ORY08987.1 - 0.00042 19.7 1.6 0.00077 18.8 1.6 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Sacchrp_dh_NADP PF03435.18 ORY08987.1 - 0.00099 19.4 0.1 0.0018 18.5 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Glu_dehyd_C PF16912.5 ORY08987.1 - 0.0012 18.3 0.0 0.0031 17.0 0.0 1.6 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 ORY08987.1 - 0.0043 18.1 0.0 0.011 16.7 0.0 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase IGFBP PF00219.18 ORY08987.1 - 0.02 15.5 0.3 0.083 13.5 0.3 2.0 1 0 0 1 1 1 0 Insulin-like growth factor binding protein UDPG_MGDP_dh_N PF03721.14 ORY08987.1 - 0.049 13.2 0.4 0.088 12.4 0.4 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Imm70 PF15601.6 ORY08987.1 - 0.12 11.9 0.0 0.29 10.7 0.0 1.6 1 0 0 1 1 1 0 Immunity protein 70 AhpC-TSA_2 PF13911.6 ORY08988.1 - 8.7e-23 80.6 0.0 1.4e-22 80.0 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 ORY08988.1 - 0.093 12.7 0.0 0.33 10.9 0.0 1.9 1 1 0 1 1 1 0 AhpC/TSA family SET PF00856.28 ORY08989.1 - 1e-15 58.5 0.1 2e-15 57.6 0.1 1.5 1 0 0 1 1 1 1 SET domain HET PF06985.11 ORY08990.1 - 5.2e-13 49.6 15.2 9.3e-10 39.0 5.2 2.4 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) NPP1 PF05630.11 ORY08992.1 - 7.3e-07 29.5 2.6 2e-06 28.1 2.6 1.6 1 1 1 2 2 2 1 Necrosis inducing protein (NPP1) Sugar_tr PF00083.24 ORY08993.1 - 5.2e-130 434.3 32.5 6e-130 434.1 32.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY08993.1 - 6e-28 97.8 55.4 3.8e-24 85.3 33.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2530 PF10745.9 ORY08993.1 - 0.016 15.4 1.4 0.016 15.4 1.4 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF2530) Pox_A14 PF05767.12 ORY08993.1 - 0.019 15.1 7.4 0.18 12.0 0.2 3.7 4 0 0 4 4 4 0 Poxvirus virion envelope protein A14 SirB PF04247.12 ORY08993.1 - 0.06 13.4 6.9 1.8 8.6 0.1 3.1 2 1 1 3 3 3 0 Invasion gene expression up-regulator, SirB HET PF06985.11 ORY08994.1 - 4.5e-27 95.2 0.5 9.6e-27 94.1 0.5 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Meth_synt_1 PF08267.12 ORY08994.1 - 0.12 11.9 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 Cobalamin-independent synthase, N-terminal domain Zip PF02535.22 ORY08995.1 - 2.7e-58 197.8 1.5 4.6e-58 197.0 1.5 1.3 1 0 0 1 1 1 1 ZIP Zinc transporter Nop16 PF09420.10 ORY08996.1 - 7.8e-59 199.2 9.3 8.9e-59 199.0 9.3 1.0 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 MFS_1 PF07690.16 ORY08997.1 - 4.7e-33 114.6 49.3 7e-32 110.7 49.3 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY08997.1 - 1.1e-11 44.3 10.4 1.1e-11 44.3 10.4 2.5 2 0 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 ORY08997.1 - 0.00013 20.4 3.5 0.00013 20.4 3.5 2.0 3 0 0 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family Phage_holin_2_1 PF04971.12 ORY08997.1 - 0.18 11.8 3.4 0.97 9.5 0.3 2.9 2 0 0 2 2 2 0 Bacteriophage P21 holin S SUR7 PF06687.12 ORY09000.1 - 0.02 14.5 0.1 0.024 14.3 0.1 1.2 1 0 0 1 1 1 0 SUR7/PalI family AA_permease_2 PF13520.6 ORY09001.1 - 9.8e-49 166.3 51.4 1.3e-48 166.0 51.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ORY09001.1 - 6.2e-24 84.4 43.7 8.2e-24 84.0 43.7 1.1 1 0 0 1 1 1 1 Amino acid permease zf-C3HC4_2 PF13923.6 ORY09002.1 - 1.7e-07 30.9 6.5 5.1e-07 29.4 6.5 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORY09002.1 - 3.4e-07 30.2 5.3 3.4e-07 30.2 5.3 1.9 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 ORY09002.1 - 4.1e-06 27.0 5.1 8.7e-06 26.0 5.1 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 ORY09002.1 - 8.3e-06 25.6 3.4 1.6e-05 24.7 3.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 ORY09002.1 - 0.00024 21.2 4.5 0.0012 18.9 4.5 2.1 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING FUSC PF04632.12 ORY09002.1 - 0.00044 18.9 0.1 0.31 9.5 0.0 2.2 1 1 1 2 2 2 2 Fusaric acid resistance protein family zf-RING_10 PF16685.5 ORY09002.1 - 0.0013 18.9 1.2 0.0023 18.0 1.2 1.4 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-RING_5 PF14634.6 ORY09002.1 - 0.0013 18.6 6.7 0.016 15.2 7.4 2.3 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 ORY09002.1 - 0.0015 18.4 6.0 0.0028 17.5 6.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 ORY09002.1 - 0.0099 15.7 4.9 0.14 12.1 1.0 2.5 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 ORY09002.1 - 0.036 13.9 1.7 0.096 12.6 1.7 1.7 1 1 0 1 1 1 0 zf-RING of BARD1-type protein PspB PF06667.12 ORY09002.1 - 0.042 13.9 0.5 0.1 12.7 0.4 1.7 2 0 0 2 2 1 0 Phage shock protein B zf-rbx1 PF12678.7 ORY09002.1 - 0.12 12.6 5.3 0.32 11.3 5.3 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-Nse PF11789.8 ORY09002.1 - 0.17 11.7 2.1 0.43 10.4 2.1 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit FdhE PF04216.12 ORY09002.1 - 0.17 11.8 6.7 0.43 10.4 6.8 1.5 1 1 0 1 1 1 0 Protein involved in formate dehydrogenase formation zf-P11 PF03854.14 ORY09002.1 - 0.41 10.3 2.6 0.63 9.8 0.3 2.3 2 0 0 2 2 2 0 P-11 zinc finger DUF1644 PF07800.12 ORY09002.1 - 1.4 8.9 5.3 0.56 10.3 1.5 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1644) Pkinase PF00069.25 ORY09003.1 - 1.4e-35 122.9 0.0 2.7e-35 122.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY09003.1 - 3.2e-18 66.0 0.0 4.7e-18 65.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase zf-C2H2_2 PF12756.7 ORY09003.1 - 1.7e-06 28.3 5.0 0.0055 17.0 0.0 2.7 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 ORY09003.1 - 0.069 14.0 0.6 0.069 14.0 0.6 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger F-box-like PF12937.7 ORY09004.1 - 9.1e-06 25.5 1.8 6.2e-05 22.8 0.2 2.5 2 0 0 2 2 2 1 F-box-like zf-C2H2_aberr PF17017.5 ORY09004.1 - 0.33 11.1 1.2 0.5 10.5 1.2 1.2 1 0 0 1 1 1 0 Aberrant zinc-finger AMP-binding PF00501.28 ORY09005.1 - 1.6e-96 323.5 0.0 1.9e-96 323.2 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORY09005.1 - 1.1e-14 55.2 0.1 2.1e-14 54.2 0.1 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PCB_OB PF17092.5 ORY09005.1 - 0.11 13.3 0.1 0.31 11.8 0.1 1.8 1 0 0 1 1 1 0 Penicillin-binding protein OB-like domain NDUF_B7 PF05676.13 ORY09006.1 - 2.2e-30 104.2 5.0 2.9e-30 103.8 5.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.10 ORY09006.1 - 0.012 15.6 2.4 0.016 15.2 2.4 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Ank_2 PF12796.7 ORY09007.1 - 8.6e-14 51.9 0.0 4.4e-05 24.0 0.0 3.3 2 1 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY09007.1 - 4.4e-11 43.1 0.1 1.4e-05 25.5 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 ORY09007.1 - 5.4e-10 39.3 0.2 6.2e-06 26.4 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY09007.1 - 1.7e-09 37.1 0.6 0.012 16.1 0.0 4.7 5 0 0 5 5 5 2 Ankyrin repeat Ank PF00023.30 ORY09007.1 - 8.1e-08 32.4 0.2 0.28 11.7 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeat KilA-N PF04383.13 ORY09007.1 - 2.4e-05 24.2 0.3 0.0003 20.6 0.1 2.7 2 1 0 2 2 2 1 KilA-N domain JAKMIP_CC3 PF16034.5 ORY09007.1 - 0.012 15.6 0.3 0.012 15.6 0.3 2.0 2 0 0 2 2 2 0 JAKMIP CC3 domain EamA PF00892.20 ORY09009.1 - 3.8e-10 40.1 20.1 6.6e-07 29.6 1.7 2.5 2 0 0 2 2 2 2 EamA-like transporter family CSG2 PF16965.5 ORY09009.1 - 0.00022 20.3 6.7 0.0011 18.0 6.7 2.1 1 1 0 1 1 1 1 Ceramide synthase regulator GRA6 PF05084.13 ORY09009.1 - 0.18 11.7 0.6 0.53 10.2 0.2 1.9 2 0 0 2 2 2 0 Granule antigen protein (GRA6) DUF3176 PF11374.8 ORY09010.1 - 2e-18 66.5 1.3 2e-18 66.5 1.3 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) HET PF06985.11 ORY09011.1 - 1.5e-23 83.8 0.0 2e-23 83.4 0.0 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PTPA PF03095.15 ORY09013.1 - 1.1e-107 360.0 0.0 1.3e-107 359.8 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein M60-like_N PF17291.2 ORY09014.1 - 0.097 12.6 0.0 0.16 11.9 0.0 1.3 1 1 0 1 1 1 0 N-terminal domain of M60-like peptidases GSHPx PF00255.19 ORY09015.1 - 1.2e-38 130.9 0.1 1.6e-38 130.6 0.1 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 ORY09015.1 - 0.0019 18.1 0.0 0.0032 17.4 0.0 1.6 1 1 0 1 1 1 1 AhpC/TSA family DUF4174 PF13778.6 ORY09015.1 - 0.035 14.6 0.0 0.06 13.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4174) Redoxin PF08534.10 ORY09015.1 - 0.13 12.0 0.2 0.15 11.8 0.2 1.4 1 1 0 1 1 1 0 Redoxin DUF349 PF03993.12 ORY09016.1 - 0.085 13.2 0.4 0.18 12.1 0.4 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF349) Med13_C PF06333.12 ORY09016.1 - 0.087 12.1 1.3 0.24 10.7 1.3 1.7 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain DSL PF01414.19 ORY09016.1 - 0.096 13.0 0.9 0.19 12.0 0.9 1.5 1 0 0 1 1 1 0 Delta serrate ligand zf-C2H2 PF00096.26 ORY09016.1 - 0.95 10.0 8.7 0.59 10.7 2.4 3.1 2 1 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY09016.1 - 3 8.9 8.4 30 5.8 1.1 3.3 2 1 0 2 2 2 0 C2H2-type zinc finger Use1 PF09753.9 ORY09018.1 - 3.9e-07 30.0 11.1 8.5e-07 29.0 11.1 1.6 1 1 0 1 1 1 1 Membrane fusion protein Use1 Glutaredoxin2_C PF04399.13 ORY09018.1 - 1 9.2 6.2 2.1 8.2 0.6 2.6 2 1 0 2 2 2 0 Glutaredoxin 2, C terminal domain Sox_N PF12444.8 ORY09018.1 - 8.6 7.6 6.8 1.4 10.1 0.7 2.5 2 1 1 3 3 3 0 Sox developmental protein N terminal DUF1771 PF08590.10 ORY09019.1 - 5.1e-23 81.2 10.6 5.1e-23 81.2 10.6 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.21 ORY09019.1 - 7e-11 42.3 0.5 2.3e-10 40.7 0.5 1.9 1 0 0 1 1 1 1 Smr domain TraC PF07820.12 ORY09020.1 - 0.3 11.5 2.3 0.35 11.2 0.3 2.1 2 0 0 2 2 2 0 TraC-like protein Ank_2 PF12796.7 ORY09021.1 - 3e-17 63.0 0.0 4.3e-07 30.4 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ORY09021.1 - 2.4e-15 56.4 0.9 8e-07 29.2 0.0 4.3 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 ORY09021.1 - 3.6e-14 52.9 0.9 1e-06 29.2 0.1 4.3 4 1 0 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY09021.1 - 6.2e-13 47.7 1.3 0.00018 21.7 0.0 6.2 6 0 0 6 6 6 2 Ankyrin repeat Ank PF00023.30 ORY09021.1 - 8.8e-12 44.9 3.9 0.00015 22.1 0.0 5.8 6 0 0 6 6 6 3 Ankyrin repeat Stanniocalcin PF03298.13 ORY09022.1 - 7.5e-05 22.1 0.4 0.00012 21.5 0.4 1.3 1 0 0 1 1 1 1 Stanniocalcin family Sugar_tr PF00083.24 ORY09023.1 - 1.3e-83 281.4 17.9 9.6e-72 242.3 12.2 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 ORY09023.1 - 1.9e-12 46.8 27.2 5.5e-10 38.7 10.2 3.0 1 1 2 3 3 3 2 Major Facilitator Superfamily gag-asp_proteas PF13975.6 ORY09024.1 - 0.0085 16.6 0.0 0.026 15.1 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF4349 PF14257.6 ORY09024.1 - 0.043 13.3 0.7 0.1 12.0 0.5 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) Asp_protease PF09668.10 ORY09024.1 - 0.17 11.7 0.0 0.34 10.7 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease Golgin_A5 PF09787.9 ORY09025.1 - 0.13 11.7 0.1 0.19 11.2 0.1 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 Pacifastin_I PF05375.13 ORY09026.1 - 4.3 7.1 11.3 0.68 9.7 5.9 2.3 2 1 1 3 3 3 0 Pacifastin inhibitor (LCMII) Phage_coat PF09063.10 ORY09027.1 - 0.047 13.7 0.1 0.047 13.7 0.1 1.1 1 0 0 1 1 1 0 Phage PP7 coat protein UEV PF05743.13 ORY09028.1 - 8.8e-37 125.7 0.0 1.6e-36 124.8 0.0 1.4 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.10 ORY09028.1 - 2.7e-23 81.7 0.0 6e-23 80.6 0.0 1.6 1 0 0 1 1 1 1 Vps23 core domain DUF3391 PF11871.8 ORY09028.1 - 0.019 15.5 0.6 0.019 15.5 0.6 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF3391) DUF4795 PF16043.5 ORY09028.1 - 0.047 13.3 1.2 0.074 12.6 1.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) Spc7 PF08317.11 ORY09028.1 - 0.087 11.7 1.9 0.13 11.1 1.9 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein WASH-7_N PF14745.6 ORY09028.1 - 0.11 10.9 0.2 0.15 10.5 0.2 1.1 1 0 0 1 1 1 0 WASH complex subunit 7, N-terminal Snapin_Pallidin PF14712.6 ORY09028.1 - 0.43 11.0 5.1 0.79 10.2 5.1 1.4 1 0 0 1 1 1 0 Snapin/Pallidin Aminotran_5 PF00266.19 ORY09029.1 - 4.6e-93 312.1 0.0 6.8e-93 311.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 ORY09029.1 - 1e-05 25.0 0.0 1.5e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 ORY09029.1 - 0.0002 20.8 0.0 0.00099 18.5 0.0 2.0 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family zf-C4 PF00105.18 ORY09029.1 - 0.013 15.9 0.6 0.037 14.5 0.6 1.7 1 0 0 1 1 1 0 Zinc finger, C4 type (two domains) BAR PF03114.18 ORY09031.1 - 7.5e-65 218.9 6.9 9.3e-65 218.6 6.9 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 ORY09031.1 - 1.1e-14 53.7 0.0 1.9e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 ORY09031.1 - 5.1e-14 51.9 0.1 8.5e-14 51.2 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 ORY09031.1 - 1.6e-11 43.7 0.1 4.4e-11 42.3 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain CT_C_D PF02682.16 ORY09031.1 - 0.051 13.3 0.4 0.13 12.0 0.4 1.6 1 0 0 1 1 1 0 Carboxyltransferase domain, subdomain C and D LXG PF04740.12 ORY09031.1 - 0.11 12.1 5.1 0.21 11.3 0.1 2.9 3 0 0 3 3 3 0 LXG domain of WXG superfamily BAR_3 PF16746.5 ORY09031.1 - 0.31 10.7 9.7 1.5 8.5 9.0 2.5 1 1 0 1 1 1 0 BAR domain of APPL family Vps5 PF09325.10 ORY09031.1 - 0.38 10.3 10.7 2.7 7.5 10.7 2.0 1 1 0 1 1 1 0 Vps5 C terminal like TMPIT PF07851.13 ORY09031.1 - 0.65 9.2 6.8 0.62 9.2 0.2 2.1 1 1 1 2 2 2 0 TMPIT-like protein Radial_spoke_3 PF06098.11 ORY09031.1 - 0.68 9.2 9.2 0.13 11.5 3.5 2.0 2 0 0 2 2 2 0 Radial spoke protein 3 DSBA PF01323.20 ORY09032.1 - 7.5e-15 55.2 0.0 8.4e-15 55.1 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Peptidase_S8 PF00082.22 ORY09034.1 - 6.3e-23 81.5 0.1 1.1e-22 80.7 0.1 1.4 1 0 0 1 1 1 1 Subtilase family HET PF06985.11 ORY09035.1 - 6.4e-25 88.2 0.3 6.4e-24 85.0 0.3 2.0 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) BTB PF00651.31 ORY09036.1 - 3.5e-14 53.0 0.0 8.6e-14 51.7 0.0 1.7 1 1 0 1 1 1 1 BTB/POZ domain Ank_2 PF12796.7 ORY09036.1 - 2.7e-12 47.1 0.1 7.2e-12 45.7 0.1 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY09036.1 - 1.7e-10 41.2 0.3 1.4e-07 31.9 0.0 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY09036.1 - 1.3e-08 34.4 0.1 1.3e-05 25.2 0.0 3.7 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 ORY09036.1 - 3.7e-07 30.3 0.4 4.1e-05 23.8 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 ORY09036.1 - 8.9e-07 29.1 0.6 6.4e-06 26.3 0.0 2.6 2 1 1 3 3 3 1 Ankyrin repeats (many copies) COesterase PF00135.28 ORY09037.1 - 2.3e-80 271.0 0.0 2.8e-80 270.6 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 ORY09037.1 - 1.6e-05 24.8 0.2 0.00025 21.0 0.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold ApeA_NTD1 PF18862.1 ORY09037.1 - 0.053 13.1 0.0 0.092 12.3 0.0 1.3 1 0 0 1 1 1 0 ApeA N-terminal domain 1 MFS_1 PF07690.16 ORY09056.1 - 1.9e-22 79.7 42.6 1.9e-22 79.7 42.6 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF3298 PF11738.8 ORY09056.1 - 0.047 14.7 0.0 0.097 13.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3298) zf-U1 PF06220.12 ORY09057.1 - 1e-07 31.6 0.3 1.6e-07 30.9 0.3 1.3 1 0 0 1 1 1 1 U1 zinc finger UPF0524 PF15823.5 ORY09057.1 - 0.034 13.6 0.2 0.07 12.5 0.0 1.6 2 0 0 2 2 2 0 UPF0524 of C3orf70 SPT16 PF08644.11 ORY09057.1 - 0.076 13.2 3.2 4.3 7.5 0.0 3.0 3 0 0 3 3 3 0 FACT complex subunit (SPT16/CDC68) PAP2 PF01569.21 ORY09058.1 - 6.1e-26 90.8 3.0 6.1e-26 90.8 3.0 2.2 2 2 0 2 2 2 1 PAP2 superfamily Ank_5 PF13857.6 ORY09059.1 - 1.3e-11 44.5 0.0 1.3e-06 28.6 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 ORY09059.1 - 2.3e-05 24.9 0.0 3.7e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY09059.1 - 2.6e-05 24.7 0.1 0.00042 20.8 0.0 2.6 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY09059.1 - 0.0001 22.4 0.0 0.018 15.5 0.1 2.9 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 ORY09059.1 - 0.036 14.5 0.0 0.72 10.4 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeat CPL PF08144.11 ORY09060.1 - 1.5e-21 77.3 0.0 1.1e-20 74.5 0.0 2.4 3 0 0 3 3 3 1 CPL (NUC119) domain EF-G-binding_N PF07299.11 ORY09060.1 - 0.15 12.6 0.7 1.7 9.2 0.1 2.8 2 0 0 2 2 2 0 Elongation factor G-binding protein, N-terminal Linocin_M18 PF04454.12 ORY09063.1 - 0.036 13.4 0.0 0.053 12.8 0.0 1.2 1 0 0 1 1 1 0 Encapsulating protein for peroxidase TMEM171 PF15471.6 ORY09063.1 - 1.1 8.1 4.2 2.3 7.1 4.1 1.6 1 1 0 1 1 1 0 Transmembrane protein family 171 Nup160 PF11715.8 ORY09068.1 - 7.8e-122 407.6 0.0 1e-121 407.3 0.0 1.1 1 0 0 1 1 1 1 Nucleoporin Nup120/160 UQ_con PF00179.26 ORY09069.1 - 4.4e-32 110.6 0.0 7.5e-32 109.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 ORY09069.1 - 0.064 12.9 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 Prokaryotic E2 family B LapA_dom PF06305.11 ORY09070.1 - 1.3 8.9 0.0 1.3 8.9 0.0 4.1 5 0 0 5 5 5 0 Lipopolysaccharide assembly protein A domain PGG PF13962.6 ORY09070.1 - 5.9 6.7 12.2 3.7 7.4 1.3 3.2 2 1 1 3 3 3 0 Domain of unknown function SH3_1 PF00018.28 ORY09071.1 - 1.6e-08 34.0 0.1 3.5e-08 32.9 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 ORY09071.1 - 5.4e-06 26.0 0.0 9.2e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 ORY09071.1 - 4.4e-05 23.3 0.0 7.7e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain DUF1100 PF06500.11 ORY09072.1 - 3.4e-09 36.0 0.0 4.5e-09 35.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Peptidase_S9 PF00326.21 ORY09072.1 - 8.6e-08 31.9 0.0 1.7e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 ORY09072.1 - 2.1e-06 27.5 0.2 4e-06 26.6 0.2 1.4 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Esterase PF00756.20 ORY09072.1 - 7.2e-06 25.8 0.0 4.5e-05 23.2 0.0 1.9 1 1 0 1 1 1 1 Putative esterase Abhydrolase_1 PF00561.20 ORY09072.1 - 0.0006 19.5 0.0 0.015 15.0 0.1 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold BAAT_C PF08840.11 ORY09072.1 - 0.098 12.6 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Hydrolase_4 PF12146.8 ORY09072.1 - 0.13 11.5 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Ank_2 PF12796.7 ORY09073.1 - 3.6e-21 75.5 0.3 2.3e-10 40.9 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY09073.1 - 4.7e-21 74.9 1.4 4.3e-06 27.2 0.0 3.5 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY09073.1 - 3.6e-17 60.7 0.2 0.00017 21.8 0.0 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank PF00023.30 ORY09073.1 - 1.3e-15 57.1 2.4 0.00028 21.2 0.1 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 ORY09073.1 - 7.7e-13 48.4 1.1 3e-05 24.2 0.0 3.9 1 1 3 4 4 4 4 Ankyrin repeats (many copies) HEM4 PF02602.15 ORY09073.1 - 0.012 15.0 0.0 0.82 9.0 0.0 2.2 1 1 1 2 2 2 0 Uroporphyrinogen-III synthase HemD TPP_enzyme_N PF02776.18 ORY09074.1 - 2.5e-38 131.4 0.1 4.9e-38 130.4 0.1 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 ORY09074.1 - 1.2e-34 119.0 0.0 2.3e-34 118.1 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 ORY09074.1 - 6.1e-22 78.1 0.1 2.7e-21 76.0 0.0 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain B12-binding PF02310.19 ORY09074.1 - 0.001 19.1 0.5 0.003 17.6 0.5 1.8 1 0 0 1 1 1 1 B12 binding domain CO_dh PF02552.16 ORY09074.1 - 0.049 13.4 0.0 0.096 12.4 0.0 1.4 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit AMP-binding PF00501.28 ORY09075.1 - 9.2e-80 268.3 0.0 1.3e-79 267.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORY09075.1 - 8.5e-14 52.3 0.0 3.9e-13 50.2 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain PEP_mutase PF13714.6 ORY09076.1 - 3.5e-37 128.1 0.0 4.5e-37 127.8 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 ORY09076.1 - 7.3e-18 64.4 0.2 1.1e-17 63.8 0.2 1.2 1 0 0 1 1 1 1 Isocitrate lyase family AflR PF08493.10 ORY09077.1 - 2.1e-16 60.3 1.3 2.1e-16 60.3 1.3 1.8 1 1 1 2 2 2 1 Aflatoxin regulatory protein MutS_V PF00488.21 ORY09079.1 - 8.7e-52 175.9 0.0 1.6e-51 175.0 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 ORY09079.1 - 1.8e-17 64.2 0.0 4.2e-17 63.0 0.0 1.7 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.18 ORY09079.1 - 0.0041 17.4 0.0 0.01 16.2 0.0 1.6 1 0 0 1 1 1 1 MutS family domain IV DUF1073 PF06381.11 ORY09079.1 - 0.03 13.1 0.0 0.049 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1073) AAA_2 PF07724.14 ORY09080.1 - 7.5e-46 156.4 0.0 9.4e-44 149.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 ORY09080.1 - 2.2e-35 120.7 11.4 2.4e-35 120.6 2.6 2.6 2 0 0 2 2 2 1 AAA lid domain ClpB_D2-small PF10431.9 ORY09080.1 - 9e-26 89.8 2.2 1.1e-25 89.5 0.2 2.4 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 ORY09080.1 - 7.9e-19 68.4 1.1 5.1e-11 43.1 0.0 3.0 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 ORY09080.1 - 6.6e-13 48.9 0.1 1.6e-08 34.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 ORY09080.1 - 1.1e-09 38.9 0.4 0.00058 20.3 0.1 3.8 2 2 1 3 3 3 2 AAA ATPase domain Sigma54_activat PF00158.26 ORY09080.1 - 7e-09 35.6 0.3 1.9e-05 24.4 0.0 2.7 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_22 PF13401.6 ORY09080.1 - 2.1e-07 31.3 2.0 0.045 14.0 0.0 4.0 3 2 0 3 3 3 2 AAA domain TniB PF05621.11 ORY09080.1 - 1.1e-06 28.1 0.0 0.0042 16.5 0.0 3.6 2 1 0 2 2 2 1 Bacterial TniB protein AAA_18 PF13238.6 ORY09080.1 - 1.5e-05 25.5 3.0 0.029 14.9 0.0 4.0 3 1 1 4 4 4 1 AAA domain AAA_14 PF13173.6 ORY09080.1 - 2e-05 24.7 0.6 0.19 11.7 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_7 PF12775.7 ORY09080.1 - 2.2e-05 24.1 0.0 0.2 11.2 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region ATPase_2 PF01637.18 ORY09080.1 - 9.1e-05 22.5 5.6 0.3 11.0 0.2 4.2 3 1 0 3 3 3 1 ATPase domain predominantly from Archaea NACHT PF05729.12 ORY09080.1 - 0.00017 21.6 0.1 0.099 12.6 0.0 2.7 2 0 0 2 2 2 1 NACHT domain AAA_30 PF13604.6 ORY09080.1 - 0.00019 21.2 0.2 0.15 11.8 0.0 3.7 2 1 0 3 3 3 1 AAA domain IstB_IS21 PF01695.17 ORY09080.1 - 0.00028 20.7 0.7 0.29 10.9 0.0 3.1 3 1 0 3 3 3 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 ORY09080.1 - 0.00049 19.5 1.1 0.61 9.4 0.0 3.4 3 1 1 4 4 3 1 Magnesium chelatase, subunit ChlI AAA_23 PF13476.6 ORY09080.1 - 0.00055 20.5 11.3 0.031 14.8 6.9 3.4 3 0 0 3 3 3 1 AAA domain SRP54 PF00448.22 ORY09080.1 - 0.00087 19.0 0.0 0.17 11.5 0.0 2.7 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Roc PF08477.13 ORY09080.1 - 0.0018 18.5 0.2 1.1 9.4 0.0 2.9 3 0 0 3 3 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_19 PF13245.6 ORY09080.1 - 0.002 18.4 1.3 0.12 12.7 0.1 3.2 2 2 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 ORY09080.1 - 0.0021 18.4 0.0 1.8 9.0 0.0 3.0 2 0 0 2 2 2 1 RNA helicase AAA_28 PF13521.6 ORY09080.1 - 0.0022 18.3 4.6 0.12 12.7 0.0 3.8 4 1 1 5 5 3 1 AAA domain AAA_24 PF13479.6 ORY09080.1 - 0.0024 17.6 0.0 3.2 7.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 ORY09080.1 - 0.0048 17.1 0.0 3.8 7.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 ORY09080.1 - 0.0073 16.3 0.0 4.3 7.4 0.0 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE UvrD-helicase PF00580.21 ORY09080.1 - 0.0086 15.6 3.7 0.2 11.1 0.1 2.3 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain ABC_tran PF00005.27 ORY09080.1 - 0.0089 16.5 1.6 6 7.4 0.0 3.4 3 1 0 3 3 3 0 ABC transporter TrwB_AAD_bind PF10412.9 ORY09080.1 - 0.0092 14.9 2.1 0.6 9.0 0.1 2.7 3 0 0 3 3 2 1 Type IV secretion-system coupling protein DNA-binding domain DUF815 PF05673.13 ORY09080.1 - 0.011 14.9 0.1 0.34 10.0 0.1 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF815) Ead_Ea22 PF13935.6 ORY09080.1 - 0.022 15.4 9.2 1.7 9.3 6.9 2.9 2 1 0 2 2 2 0 Ead/Ea22-like protein RsgA_GTPase PF03193.16 ORY09080.1 - 0.024 14.5 0.8 5.1 7.0 0.0 3.0 3 0 0 3 3 3 0 RsgA GTPase Zeta_toxin PF06414.12 ORY09080.1 - 0.041 13.1 1.1 6.7 5.9 0.0 2.9 3 0 0 3 3 2 0 Zeta toxin AAA_6 PF12774.7 ORY09080.1 - 0.045 12.7 0.0 1.2 8.1 0.0 2.3 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region PduV-EutP PF10662.9 ORY09080.1 - 0.056 13.2 0.0 3 7.6 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ERM PF00769.19 ORY09080.1 - 0.066 13.0 13.0 0.12 12.2 13.0 1.4 1 0 0 1 1 1 0 Ezrin/radixin/moesin family ResIII PF04851.15 ORY09080.1 - 0.078 13.0 3.6 2.6 8.0 0.0 3.2 3 1 0 4 4 3 0 Type III restriction enzyme, res subunit ATP_bind_1 PF03029.17 ORY09080.1 - 0.2 11.4 1.3 1.9 8.2 0.0 2.6 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein DUF2009 PF09418.10 ORY09080.1 - 0.42 9.6 2.4 0.68 8.9 2.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2009) PTPlike_phytase PF14566.6 ORY09080.1 - 0.47 10.6 3.8 1.2 9.2 3.8 1.7 1 0 0 1 1 1 0 Inositol hexakisphosphate DUF87 PF01935.17 ORY09080.1 - 0.88 9.6 7.0 46 4.0 0.0 3.3 3 0 0 3 3 3 0 Helicase HerA, central domain V_ATPase_I PF01496.19 ORY09080.1 - 0.94 7.3 3.1 1.3 6.9 3.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Cob_adeno_trans PF01923.18 ORY09080.1 - 1 9.5 4.7 2.5 8.2 4.7 1.6 1 0 0 1 1 1 0 Cobalamin adenosyltransferase OEP PF02321.18 ORY09080.1 - 1.5 8.6 12.8 3 7.6 12.8 1.4 1 0 0 1 1 1 0 Outer membrane efflux protein MRP-S27 PF10037.9 ORY09080.1 - 1.7 7.4 8.1 2.6 6.8 8.1 1.2 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 DUF4094 PF13334.6 ORY09080.1 - 2.6 8.5 13.6 0.63 10.5 0.6 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4094) UPF0242 PF06785.11 ORY09080.1 - 5 7.2 14.2 12 6.0 14.2 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus EF1_GNE PF00736.19 ORY09081.1 - 2.1e-33 114.3 1.7 4.4e-33 113.3 1.7 1.5 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 ORY09081.1 - 6.3e-14 52.1 10.2 6.3e-14 52.1 10.2 2.5 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_3 PF14497.6 ORY09081.1 - 0.073 13.3 0.3 0.5 10.6 0.0 2.1 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 ORY09081.1 - 0.13 12.5 0.9 1.5 9.1 0.0 2.8 3 1 0 3 3 3 0 Glutathione S-transferase, C-terminal domain Fes1 PF08609.10 ORY09081.1 - 1.2 10.0 4.5 0.5 11.3 0.4 2.1 2 0 0 2 2 2 0 Nucleotide exchange factor Fes1 MFS_1 PF07690.16 ORY09082.1 - 8.2e-38 130.2 37.0 8.2e-38 130.2 37.0 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily IMUP PF15761.5 ORY09082.1 - 0.68 10.7 6.1 1.2 9.8 6.1 1.3 1 0 0 1 1 1 0 Immortalisation up-regulated protein AltA1 PF16541.5 ORY09083.1 - 0.0074 17.1 0.1 0.0094 16.8 0.1 1.2 1 0 0 1 1 1 1 Alternaria alternata allergen 1 VPS9 PF02204.18 ORY09084.1 - 8.1e-17 61.3 0.0 1.9e-16 60.1 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ank_5 PF13857.6 ORY09084.1 - 2.1e-14 53.4 0.0 1.5e-12 47.5 0.0 3.9 5 0 0 5 5 5 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 ORY09084.1 - 6.7e-14 52.2 0.1 0.00081 19.9 0.0 4.6 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ORY09084.1 - 2e-05 24.6 0.0 0.25 12.0 0.0 4.8 4 0 0 4 4 4 1 Ankyrin repeat Ank PF00023.30 ORY09084.1 - 0.00052 20.3 0.0 4.1 8.0 0.0 4.5 4 0 0 4 4 4 1 Ankyrin repeat Ank_4 PF13637.6 ORY09084.1 - 0.00054 20.5 0.1 0.25 12.0 0.0 4.3 3 1 1 4 4 4 2 Ankyrin repeats (many copies) PX PF00787.24 ORY09084.1 - 0.01 15.8 0.0 0.031 14.3 0.0 1.8 1 0 0 1 1 1 0 PX domain SesA PF17107.5 ORY09085.1 - 9.3e-06 25.8 1.6 0.007 16.6 0.0 2.6 2 0 0 2 2 2 2 N-terminal domain on NACHT_NTPase and P-loop NTPases NACHT PF05729.12 ORY09085.1 - 4.7e-05 23.4 0.2 0.00058 19.8 0.0 2.7 2 1 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 ORY09085.1 - 0.00039 20.7 0.0 0.0022 18.3 0.0 2.2 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 ORY09085.1 - 0.0028 18.1 0.0 0.012 16.0 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain ABC_tran PF00005.27 ORY09085.1 - 0.003 18.1 1.5 0.067 13.7 0.0 2.7 3 0 0 3 3 2 1 ABC transporter NB-ARC PF00931.22 ORY09085.1 - 0.0051 16.0 0.2 0.64 9.2 0.0 3.4 3 1 1 4 4 4 1 NB-ARC domain AAA_29 PF13555.6 ORY09085.1 - 0.0071 16.1 0.1 0.015 15.1 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain EF-hand_13 PF17958.1 ORY09085.1 - 0.011 15.5 0.0 0.35 10.7 0.0 2.9 2 1 1 3 3 3 0 EF-hand domain dNK PF01712.19 ORY09085.1 - 0.011 15.5 0.1 6.6 6.5 0.0 2.5 2 0 0 2 2 2 0 Deoxynucleoside kinase AAA_30 PF13604.6 ORY09085.1 - 0.025 14.3 0.0 0.059 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 ORY09085.1 - 0.028 14.9 1.4 0.22 12.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 ORY09085.1 - 0.042 14.0 0.5 0.24 11.6 0.0 2.4 3 0 0 3 3 2 0 AAA domain NPV_P10 PF05531.12 ORY09085.1 - 0.11 13.0 2.1 0.52 10.8 1.0 2.7 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF948 PF06103.11 ORY09085.1 - 0.2 11.9 0.6 1.7 8.9 0.3 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) HIP1_clath_bdg PF16515.5 ORY09085.1 - 0.56 10.8 2.4 0.81 10.3 0.7 2.0 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 FAD_binding_4 PF01565.23 ORY09086.1 - 5e-21 74.9 0.6 1.1e-20 73.8 0.6 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 ORY09086.1 - 2.1e-12 46.9 0.3 3.8e-12 46.1 0.3 1.4 1 0 0 1 1 1 1 Berberine and berberine like Rhomboid PF01694.22 ORY09087.1 - 1.7e-17 63.8 8.1 3.8e-17 62.7 8.1 1.6 1 0 0 1 1 1 1 Rhomboid family CRISPR_Cas6 PF10040.9 ORY09087.1 - 0.18 12.5 1.0 2 9.1 1.0 2.5 1 1 0 1 1 1 0 CRISPR-associated endoribonuclease Cas6 Thioesterase PF00975.20 ORY09088.1 - 0.018 15.1 0.0 0.021 14.9 0.0 1.1 1 0 0 1 1 1 0 Thioesterase domain Syntaxin-6_N PF09177.11 ORY09088.1 - 0.038 14.5 0.4 0.065 13.8 0.4 1.4 1 0 0 1 1 1 0 Syntaxin 6, N-terminal DivIC PF04977.15 ORY09088.1 - 0.067 13.0 0.3 0.13 12.0 0.1 1.5 1 1 0 1 1 1 0 Septum formation initiator Tropomyosin_1 PF12718.7 ORY09091.1 - 0.42 10.8 1.8 0.68 10.1 1.8 1.2 1 0 0 1 1 1 0 Tropomyosin like Med16 PF11635.8 ORY09092.1 - 8.2e-149 496.9 0.0 9.5e-149 496.7 0.0 1.0 1 0 0 1 1 1 1 Mediator complex subunit 16 Cnd2 PF05786.14 ORY09092.1 - 0.0043 15.8 0.0 0.0061 15.3 0.0 1.2 1 0 0 1 1 1 1 Condensin complex subunit 2 SIR2 PF02146.17 ORY09093.1 - 1.3e-25 90.4 0.0 4.2e-25 88.7 0.0 1.9 1 1 0 1 1 1 1 Sir2 family PDE8 PF08629.10 ORY09093.1 - 1.3 9.0 6.3 1.6 8.8 1.2 2.9 2 0 0 2 2 2 0 PDE8 phosphodiesterase RR_TM4-6 PF06459.12 ORY09093.1 - 3.5 7.4 7.6 6 6.6 7.6 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PI-PLC-X PF00388.19 ORY09094.1 - 1.2e-11 44.4 0.0 1.9e-11 43.7 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain HET PF06985.11 ORY09096.1 - 1.5e-27 96.7 4.1 1e-26 94.0 4.1 2.1 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) 4HBT PF03061.22 ORY09097.1 - 1.9e-12 47.4 0.0 1.2e-11 44.8 0.0 2.2 2 0 0 2 2 2 1 Thioesterase superfamily Tim44 PF04280.15 ORY09098.1 - 1e-37 129.5 0.0 1.3e-36 125.9 0.0 2.2 2 0 0 2 2 2 1 Tim44-like domain Zip PF02535.22 ORY09098.1 - 0.63 9.2 1.6 0.91 8.7 1.6 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Ribosomal_S11 PF00411.19 ORY09099.1 - 7.3e-11 42.5 0.0 1.2e-10 41.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S11 Peptidase_C97 PF05903.14 ORY09100.1 - 7.5e-33 113.5 0.0 9.5e-33 113.2 0.0 1.1 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.13 ORY09100.1 - 0.00034 20.9 0.0 0.00061 20.1 0.0 1.3 1 0 0 1 1 1 1 Lecithin retinol acyltransferase DUF778 PF05608.12 ORY09100.1 - 0.01 16.2 0.4 0.019 15.3 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF778) YchF-GTPase_C PF06071.13 ORY09101.1 - 8.3e-33 112.4 0.1 2.7e-32 110.8 0.1 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 ORY09101.1 - 2.1e-16 60.0 0.0 8.3e-16 58.1 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 ORY09101.1 - 0.00067 19.2 0.0 0.0015 18.1 0.0 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.21 ORY09101.1 - 0.0034 17.4 0.1 0.015 15.4 0.0 2.1 2 0 0 2 2 2 1 TGS domain AAA_23 PF13476.6 ORY09101.1 - 0.056 13.9 0.0 3.9 7.9 0.0 2.4 3 0 0 3 3 3 0 AAA domain tRNA-synt_His PF13393.6 ORY09102.1 - 2.2e-38 132.3 0.0 3.1e-31 108.8 0.0 2.1 2 0 0 2 2 2 2 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 ORY09102.1 - 1.5e-12 47.5 0.0 2.7e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain HGTP_anticodon2 PF12745.7 ORY09102.1 - 0.0004 20.0 0.0 0.00082 19.0 0.0 1.4 1 0 0 1 1 1 1 Anticodon binding domain of tRNAs tRNA-synt_2 PF00152.20 ORY09102.1 - 0.0076 15.4 0.0 0.051 12.7 0.0 2.1 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) Ribosomal_60s PF00428.19 ORY09102.1 - 0.012 16.2 0.1 0.032 14.8 0.1 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein tRNA-synt_2d PF01409.20 ORY09102.1 - 0.14 11.6 0.0 0.29 10.6 0.0 1.5 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) Pkinase PF00069.25 ORY09103.1 - 5.8e-68 229.1 0.0 1.1e-67 228.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY09103.1 - 4.7e-37 127.7 0.0 9.6e-37 126.7 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY09103.1 - 0.0001 21.8 0.0 0.00027 20.3 0.0 1.7 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 ORY09103.1 - 0.00018 21.5 0.0 0.00038 20.4 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 ORY09103.1 - 0.0045 16.1 0.0 0.0084 15.2 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 Pkinase_fungal PF17667.1 ORY09103.1 - 0.024 13.4 0.0 0.11 11.2 0.0 1.9 2 0 0 2 2 2 0 Fungal protein kinase Ammonium_transp PF00909.21 ORY09105.1 - 3.4e-117 391.5 25.4 4e-117 391.3 25.4 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family SpoV PF08183.11 ORY09105.1 - 9.9 6.2 6.2 0.96 9.5 0.5 2.3 2 0 0 2 2 2 0 Stage V sporulation protein family MMgT PF10270.9 ORY09106.1 - 5.1e-29 100.6 0.0 6.2e-29 100.3 0.0 1.1 1 0 0 1 1 1 1 Membrane magnesium transporter FAD_binding_5 PF00941.21 ORY09107.1 - 0.11 12.2 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain in molybdopterin dehydrogenase Sas10 PF09368.10 ORY09108.1 - 4.9e-29 100.6 8.6 4.9e-29 100.6 8.6 3.3 4 0 0 4 4 4 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 ORY09108.1 - 1.7e-10 41.3 0.0 1.7e-10 41.3 0.0 3.0 3 0 0 3 3 3 1 Sas10/Utp3/C1D family adh_short PF00106.25 ORY09109.1 - 4.4e-23 81.7 0.0 3.3e-22 78.9 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY09109.1 - 9.2e-15 54.8 0.1 1.2e-13 51.2 0.1 2.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY09109.1 - 4.7e-09 36.4 0.0 9.5e-07 28.9 0.0 2.1 2 0 0 2 2 2 1 KR domain THF_DHG_CYH_C PF02882.19 ORY09109.1 - 0.01 15.1 0.0 0.019 14.3 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_7 PF13241.6 ORY09109.1 - 0.013 15.9 0.0 0.023 15.1 0.0 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding Epimerase PF01370.21 ORY09109.1 - 0.023 14.2 0.0 0.035 13.6 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 ORY09109.1 - 0.035 14.0 0.0 0.091 12.6 0.0 1.7 1 0 0 1 1 1 0 NAD(P)H-binding DFP PF04127.15 ORY09109.1 - 0.082 12.7 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein 2-Hacid_dh_C PF02826.19 ORY09109.1 - 0.12 11.7 0.0 0.34 10.3 0.0 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain MHCassoc_trimer PF08831.10 ORY09109.1 - 0.14 12.2 0.0 2.3 8.3 0.0 2.4 2 0 0 2 2 2 0 Class II MHC-associated invariant chain trimerisation domain 3HCDH_N PF02737.18 ORY09109.1 - 0.15 11.9 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 ORY09109.1 - 0.15 12.1 0.0 0.33 11.0 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase CoA_binding_2 PF13380.6 ORY09109.1 - 0.16 12.5 0.0 0.26 11.8 0.0 1.4 1 0 0 1 1 1 0 CoA binding domain ABC_tran PF00005.27 ORY09111.1 - 0.00012 22.6 0.1 0.00045 20.7 0.0 2.0 2 0 0 2 2 2 1 ABC transporter zf-RING_UBOX PF13445.6 ORY09111.1 - 0.00058 19.8 7.7 0.0016 18.4 7.7 1.8 1 0 0 1 1 1 1 RING-type zinc-finger Zeta_toxin PF06414.12 ORY09111.1 - 0.0022 17.3 0.0 0.0046 16.3 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin zf-C3HC4 PF00097.25 ORY09111.1 - 0.0047 16.8 8.4 0.0094 15.8 8.0 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORY09111.1 - 0.0063 16.8 8.0 0.013 15.8 8.0 1.5 1 0 0 1 1 1 1 Ring finger domain BTG PF07742.12 ORY09111.1 - 0.014 15.3 0.0 0.048 13.5 0.0 1.9 1 0 0 1 1 1 0 BTG family AAA_16 PF13191.6 ORY09111.1 - 0.016 15.6 0.1 0.21 11.9 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain RsgA_GTPase PF03193.16 ORY09111.1 - 0.017 15.0 0.0 0.034 14.0 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase MMR_HSR1 PF01926.23 ORY09111.1 - 0.042 13.9 0.0 0.1 12.7 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase DUF87 PF01935.17 ORY09111.1 - 0.043 13.9 0.0 0.14 12.3 0.0 1.8 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_29 PF13555.6 ORY09111.1 - 0.053 13.3 0.0 0.15 11.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 ORY09111.1 - 0.073 13.6 0.2 0.42 11.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 ORY09111.1 - 0.084 13.2 0.0 0.3 11.4 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.7 ORY09111.1 - 0.15 11.0 0.0 0.3 9.9 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain zf-C3HC4_4 PF15227.6 ORY09111.1 - 0.62 10.3 10.7 5.8 7.2 10.6 2.3 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 ORY09111.1 - 0.76 9.8 12.2 0.12 12.4 8.0 1.8 2 0 0 2 2 1 0 zinc-RING finger domain Prok-RING_4 PF14447.6 ORY09111.1 - 0.86 9.5 11.0 0.39 10.6 6.5 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 ORY09111.1 - 1.4 8.8 11.7 0.2 11.5 6.9 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Patatin PF01734.22 ORY09112.1 - 4.1e-10 40.2 0.0 1.2e-09 38.7 0.0 1.7 2 0 0 2 2 2 1 Patatin-like phospholipase DrrA_P4M PF14860.6 ORY09112.1 - 0.09 12.6 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 DrrA phosphatidylinositol 4-phosphate binding domain Mito_carr PF00153.27 ORY09113.1 - 6.7e-23 80.4 0.0 7.2e-23 80.3 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial carrier protein TPR_10 PF13374.6 ORY09124.1 - 8.4e-114 368.8 8.1 5.8e-14 51.4 0.0 11.1 10 1 0 10 10 10 9 Tetratricopeptide repeat TPR_12 PF13424.6 ORY09124.1 - 2.5e-111 364.1 25.5 2.9e-19 69.1 0.3 8.8 1 1 7 9 9 9 9 Tetratricopeptide repeat TPR_7 PF13176.6 ORY09124.1 - 2.8e-32 108.4 3.5 0.0062 16.5 0.0 9.2 9 0 0 9 9 8 7 Tetratricopeptide repeat TPR_17 PF13431.6 ORY09124.1 - 3.6e-17 61.4 0.3 2.8 8.5 0.0 7.8 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_1 PF00515.28 ORY09124.1 - 5.7e-16 57.6 1.3 0.81 9.6 0.0 8.5 9 0 0 9 9 9 4 Tetratricopeptide repeat PPR PF01535.20 ORY09124.1 - 2.7e-12 46.0 0.4 14 6.2 0.0 8.3 8 0 0 8 8 8 0 PPR repeat TPR_2 PF07719.17 ORY09124.1 - 7e-12 44.5 2.6 5 7.5 0.5 8.5 9 0 0 9 9 8 1 Tetratricopeptide repeat NB-ARC PF00931.22 ORY09124.1 - 4.7e-11 42.3 0.0 1.3e-10 41.0 0.0 1.7 1 0 0 1 1 1 1 NB-ARC domain TPR_19 PF14559.6 ORY09124.1 - 2e-08 34.6 0.0 2.6 8.6 0.0 5.6 4 2 0 4 4 4 2 Tetratricopeptide repeat NRBF2_MIT PF17169.4 ORY09124.1 - 4.7e-08 33.1 0.1 42 4.4 0.0 7.8 8 0 0 8 8 8 0 MIT domain of nuclear receptor-binding factor 2 TPR_MalT PF17874.1 ORY09124.1 - 8.8e-08 31.9 13.1 0.00098 18.6 3.6 3.4 1 1 2 3 3 3 3 MalT-like TPR region TPR_14 PF13428.6 ORY09124.1 - 1.7e-07 31.4 0.3 0.79 10.7 0.0 7.4 7 1 1 8 8 7 1 Tetratricopeptide repeat PAC3 PF10178.9 ORY09124.1 - 1.2e-06 28.6 1.7 5.8 7.1 0.0 6.6 1 1 6 7 7 7 1 Proteasome assembly chaperone 3 DUF3322 PF11795.8 ORY09124.1 - 2.8e-06 27.5 0.1 9.5 6.2 0.0 5.6 1 1 2 5 5 5 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) TPR_8 PF13181.6 ORY09124.1 - 1.5e-05 24.8 10.6 18 5.8 0.0 7.4 8 0 0 8 8 7 0 Tetratricopeptide repeat A2M PF00207.22 ORY09124.1 - 2.6e-05 24.0 1.4 2 8.3 0.0 4.9 2 1 4 6 6 6 1 Alpha-2-macroglobulin family DUF4404 PF14357.6 ORY09124.1 - 0.00013 22.6 13.0 2.9 8.6 0.2 5.8 3 3 2 5 5 5 2 Domain of unknown function (DUF4404) TPR_16 PF13432.6 ORY09124.1 - 0.00021 21.8 0.7 7 7.4 0.0 6.5 6 3 1 7 7 6 0 Tetratricopeptide repeat IFRD PF05004.13 ORY09124.1 - 0.00068 18.8 9.0 7.1 5.6 0.1 5.5 1 1 4 6 6 6 0 Interferon-related developmental regulator (IFRD) DUF1925 PF09094.11 ORY09124.1 - 0.0056 17.0 18.3 29 5.1 0.1 8.2 3 1 6 9 9 8 0 Domain of unknown function (DUF1925) Polysacc_deac_2 PF04748.13 ORY09124.1 - 0.026 13.7 0.1 0.5 9.5 0.0 3.0 2 1 1 3 3 3 0 Divergent polysaccharide deacetylase Gly_radical PF01228.21 ORY09124.1 - 0.057 14.0 6.4 25 5.5 0.2 4.2 3 2 1 4 4 4 0 Glycine radical AAA_16 PF13191.6 ORY09124.1 - 0.064 13.6 0.2 0.5 10.7 0.2 2.4 1 1 0 1 1 1 0 AAA ATPase domain Sipho_tail PF05709.11 ORY09124.1 - 0.072 12.5 0.0 8.2 5.8 0.0 3.1 2 1 1 3 3 3 0 Phage tail protein RasGEF_N PF00618.20 ORY09124.1 - 0.089 13.0 0.5 0.22 11.7 0.5 1.6 1 0 0 1 1 1 0 RasGEF N-terminal motif Gln_amidase PF15644.6 ORY09124.1 - 0.22 12.6 2.7 69 4.5 0.0 4.3 2 1 0 4 4 3 0 Papain fold toxin 1, glutamine deamidase ORC3_N PF07034.11 ORY09124.1 - 1.5 7.8 12.7 6.4 5.8 0.6 4.8 2 1 4 6 6 6 0 Origin recognition complex (ORC) subunit 3 N-terminus Tli4_C PF18426.1 ORY09124.1 - 8.4 6.7 7.9 27 5.0 0.1 4.3 2 1 5 7 7 7 0 Tle cognate immunity protein 4 C-terminal domain MNE1 PF13762.6 ORY09124.1 - 8.9 6.3 17.0 12 5.8 0.0 6.1 8 0 0 8 8 6 0 Mitochondrial splicing apparatus component Pro-kuma_activ PF09286.11 ORY09125.1 - 4.9e-36 124.1 0.1 1.3e-35 122.8 0.2 1.6 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 ORY09125.1 - 3.7e-06 26.4 0.1 6e-06 25.7 0.1 1.2 1 0 0 1 1 1 1 Subtilase family p450 PF00067.22 ORY09126.1 - 3.4e-07 29.4 0.0 4.6e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 2OG-FeII_Oxy_3 PF13640.6 ORY09127.1 - 1.3e-08 35.6 0.0 2.7e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Amidohydro_2 PF04909.14 ORY09129.1 - 1.4e-27 97.2 0.1 1.8e-27 96.9 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase SabA_adhesion PF18304.1 ORY09130.1 - 0.41 9.8 2.9 0.19 11.0 0.1 1.7 2 0 0 2 2 2 0 SabA N-terminal extracellular adhesion domain BUD22 PF09073.10 ORY09130.1 - 5.5 6.2 41.2 6.4 6.0 14.4 2.2 2 0 0 2 2 2 0 BUD22 GMC_oxred_N PF00732.19 ORY09131.1 - 1.4e-50 172.3 0.0 9.6e-50 169.6 0.0 2.2 2 1 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 ORY09131.1 - 1.2e-26 94.0 0.0 2.7e-26 92.8 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 ORY09131.1 - 5.8e-05 22.3 0.1 0.29 10.2 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 ORY09131.1 - 6.8e-05 22.2 0.1 0.02 14.1 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ORY09131.1 - 0.00025 20.4 0.4 0.1 11.8 0.1 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ORY09131.1 - 0.00027 20.6 0.0 0.00081 19.1 0.0 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ORY09131.1 - 0.00034 20.8 0.1 0.00085 19.5 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 ORY09131.1 - 0.0028 16.9 1.2 0.06 12.6 0.2 2.7 2 1 1 3 3 3 1 Thi4 family HI0933_like PF03486.14 ORY09131.1 - 0.0056 15.4 0.2 0.49 9.0 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein TrkA_N PF02254.18 ORY09131.1 - 0.052 13.8 0.2 0.11 12.8 0.2 1.5 1 0 0 1 1 1 0 TrkA-N domain Lycopene_cycl PF05834.12 ORY09131.1 - 0.084 11.9 0.0 0.2 10.7 0.0 1.6 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_9 PF13454.6 ORY09131.1 - 0.14 12.2 0.1 0.68 9.9 0.1 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox PF00070.27 ORY09131.1 - 0.16 12.5 0.1 0.68 10.5 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Glyco_hydro_61 PF03443.14 ORY09132.1 - 2.1e-53 181.3 0.1 2.6e-53 181.0 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CI-B14_5a PF07347.12 ORY09133.1 - 0.072 13.0 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) zf-RING_5 PF14634.6 ORY09134.1 - 5.5e-05 23.0 3.8 0.00011 22.1 3.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain DUF4201 PF13870.6 ORY09134.1 - 0.0041 16.9 5.5 0.0067 16.2 5.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) DUF4349 PF14257.6 ORY09134.1 - 0.023 14.2 1.0 0.058 12.8 1.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) HMMR_N PF15905.5 ORY09134.1 - 0.034 13.6 3.4 0.056 12.9 3.4 1.3 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal TMF_TATA_bd PF12325.8 ORY09134.1 - 0.045 14.0 5.8 0.1 12.8 5.5 1.7 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding GAS PF13851.6 ORY09134.1 - 0.078 12.3 8.9 0.13 11.6 8.9 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding YabA PF06156.13 ORY09134.1 - 0.11 13.1 1.3 0.39 11.4 1.1 2.0 1 1 1 2 2 2 0 Initiation control protein YabA DegS PF05384.11 ORY09134.1 - 0.16 11.5 7.8 0.27 10.7 7.8 1.3 1 0 0 1 1 1 0 Sensor protein DegS Cob_adeno_trans PF01923.18 ORY09134.1 - 0.31 11.2 1.8 0.53 10.4 1.8 1.3 1 0 0 1 1 1 0 Cobalamin adenosyltransferase DUF5344 PF17279.2 ORY09134.1 - 0.5 11.0 3.4 0.84 10.3 2.7 1.8 1 1 1 2 2 2 0 Family of unknown function (DUF5344) BLOC1_2 PF10046.9 ORY09134.1 - 0.79 10.1 2.9 1.5 9.2 2.9 1.5 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FapA PF03961.13 ORY09134.1 - 2.1 6.9 3.0 2.9 6.4 3.0 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Spc7 PF08317.11 ORY09134.1 - 2.4 6.9 7.6 3.6 6.4 7.6 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein APG6_N PF17675.1 ORY09134.1 - 7.9 7.0 10.1 22 5.6 10.1 1.7 1 1 0 1 1 1 0 Apg6 coiled-coil region tRNA-synt_1g PF09334.11 ORY09135.1 - 3.4e-154 513.3 0.8 4.4e-154 513.0 0.8 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 ORY09135.1 - 1.2e-08 33.7 0.4 4.2e-07 28.6 0.0 2.7 2 1 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 ORY09135.1 - 0.0037 17.2 0.1 0.0083 16.1 0.1 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 ORY09135.1 - 0.0074 15.7 0.1 0.039 13.3 0.0 2.1 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain Yae1_N PF09811.9 ORY09136.1 - 1.5e-08 34.2 2.1 3.8e-08 32.9 2.1 1.8 1 0 0 1 1 1 1 Essential protein Yae1, N terminal Ku_C PF03730.14 ORY09136.1 - 0.0012 19.5 0.1 0.0063 17.2 0.0 2.0 2 0 0 2 2 2 1 Ku70/Ku80 C-terminal arm BPL_LplA_LipB PF03099.19 ORY09137.1 - 0.0038 17.1 0.0 0.041 13.8 0.0 2.2 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family FAD_binding_3 PF01494.19 ORY09138.1 - 3.7e-35 121.8 0.0 5.5e-35 121.2 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 ORY09138.1 - 0.003 17.2 0.0 0.014 15.0 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 ORY09138.1 - 0.02 13.9 0.8 1.4 7.9 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein zf-C2H2_4 PF13894.6 ORY09140.1 - 0.0041 17.9 13.6 0.076 13.9 0.1 4.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORY09140.1 - 0.023 15.0 6.9 0.49 10.7 0.1 3.8 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 ORY09140.1 - 4.3 8.0 14.6 1.8 9.2 0.1 3.5 3 0 0 3 3 3 0 Zinc finger, C2H2 type Lar_restr_allev PF14354.6 ORY09140.1 - 7.4 7.0 9.0 6 7.3 3.7 2.7 2 1 0 2 2 2 0 Restriction alleviation protein Lar zf-met PF12874.7 ORY09140.1 - 8 7.0 11.8 6.6 7.3 0.2 4.0 4 0 0 4 4 4 0 Zinc-finger of C2H2 type SET PF00856.28 ORY09142.1 - 5.4e-13 49.7 0.8 7.6e-12 45.9 0.8 2.4 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.18 ORY09142.1 - 3.9e-09 36.5 11.4 9.8e-09 35.2 11.4 1.7 1 0 0 1 1 1 1 MYND finger TPR_10 PF13374.6 ORY09142.1 - 0.14 12.1 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.6 ORY09144.1 - 4.7e-27 94.1 17.3 3.2e-06 27.3 0.8 8.0 5 3 3 8 8 8 7 Tetratricopeptide repeat TPR_10 PF13374.6 ORY09144.1 - 3.5e-19 68.0 11.2 7.4e-06 25.7 0.0 9.2 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_2 PF07719.17 ORY09144.1 - 1.9e-09 36.9 8.5 1.4 9.2 0.1 8.6 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_MalT PF17874.1 ORY09144.1 - 4.4e-09 36.2 0.1 0.023 14.1 0.0 3.7 3 1 1 4 4 4 2 MalT-like TPR region NB-ARC PF00931.22 ORY09144.1 - 1.8e-07 30.6 0.0 4.4e-07 29.3 0.0 1.7 1 0 0 1 1 1 1 NB-ARC domain TPR_1 PF00515.28 ORY09144.1 - 1.8e-06 27.5 0.5 1.2 9.0 0.0 6.1 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_16 PF13432.6 ORY09144.1 - 0.00021 21.9 4.3 12 6.6 0.2 5.6 4 1 2 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.6 ORY09144.1 - 0.001 19.7 6.6 0.39 11.7 0.1 6.3 8 0 0 8 8 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 ORY09144.1 - 0.0016 18.9 0.6 0.15 12.6 0.2 4.0 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 ORY09144.1 - 0.0016 18.5 10.4 6.2 7.3 0.0 6.7 7 0 0 7 7 7 1 Tetratricopeptide repeat AAA_16 PF13191.6 ORY09144.1 - 0.0055 17.1 0.0 0.016 15.6 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 ORY09144.1 - 0.013 15.8 0.0 0.05 13.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain TPR_7 PF13176.6 ORY09144.1 - 0.016 15.2 7.6 19 5.6 0.3 6.5 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_4 PF07721.14 ORY09144.1 - 0.019 15.6 0.1 1.6 9.6 0.2 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 ORY09144.1 - 0.038 14.6 2.3 8 7.3 0.0 5.0 5 0 0 5 5 3 0 Tetratricopeptide repeat AAA_14 PF13173.6 ORY09144.1 - 0.14 12.2 0.0 0.33 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain Glyco_hydro_36 PF17167.4 ORY09145.1 - 8e-65 219.2 0.0 1.4e-64 218.4 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase 36 superfamily, catalytic domain Glyco_transf_36 PF06165.11 ORY09145.1 - 5.5e-28 98.0 0.0 8.8e-28 97.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 36 Glyco_hydro_65C PF03633.15 ORY09145.1 - 0.0013 18.6 0.0 0.0032 17.3 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, C-terminal domain Bac_rhamnosid6H PF17389.2 ORY09145.1 - 0.045 13.0 0.0 0.1 11.9 0.0 1.5 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain AstB PF04996.12 ORY09146.1 - 0.22 10.1 0.0 0.24 10.0 0.0 1.1 1 0 0 1 1 1 0 Succinylarginine dihydrolase Phage_holin_2_4 PF16082.5 ORY09147.1 - 0.035 13.8 0.1 0.054 13.2 0.1 1.2 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like FixQ PF05545.11 ORY09147.1 - 0.086 12.8 6.1 0.15 12.1 0.2 2.9 3 0 0 3 3 3 0 Cbb3-type cytochrome oxidase component FixQ PIG-Y PF15159.6 ORY09147.1 - 0.17 12.8 3.4 1.1 10.3 0.0 2.7 2 1 1 3 3 3 0 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y Patatin PF01734.22 ORY09149.1 - 2.7e-15 57.1 0.4 3.5e-12 46.9 0.4 2.4 1 1 0 1 1 1 1 Patatin-like phospholipase Sugar_tr PF00083.24 ORY09151.1 - 1.8e-49 168.8 22.9 1.5e-38 132.9 9.1 2.3 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 ORY09151.1 - 7.7e-11 41.5 35.3 7.5e-09 35.0 17.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily GST_C PF00043.25 ORY09152.1 - 1.6e-13 50.7 0.0 3.4e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 ORY09152.1 - 1e-07 31.8 0.0 2.1e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 ORY09152.1 - 6.2e-06 26.3 0.0 1.4e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Cupin_1 PF00190.22 ORY09153.1 - 5e-10 39.2 0.1 6.6e-10 38.8 0.1 1.2 1 0 0 1 1 1 1 Cupin GST_N_3 PF13417.6 ORY09154.1 - 9.9e-05 22.7 0.0 0.00019 21.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 ORY09154.1 - 0.00025 21.3 0.0 0.00048 20.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 ORY09154.1 - 0.015 15.3 0.0 0.035 14.1 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 ORY09154.1 - 0.04 14.1 0.0 0.088 13.0 0.0 1.6 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 ORY09154.1 - 0.15 12.2 0.0 0.27 11.5 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain SEEK1 PF15357.6 ORY09154.1 - 0.2 11.8 0.0 0.49 10.5 0.0 1.6 2 0 0 2 2 2 0 Psoriasis susceptibility 1 candidate 1 Pkinase PF00069.25 ORY09155.1 - 2.7e-72 243.3 0.0 5e-72 242.4 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY09155.1 - 3.2e-50 170.8 0.0 5.5e-50 170.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORY09155.1 - 0.00083 18.2 0.0 0.0022 16.8 0.0 1.8 1 1 0 1 1 1 1 Fungal protein kinase Arm PF00514.23 ORY09155.1 - 0.037 14.1 0.2 6.2 7.0 0.0 3.8 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Med15_fungi PF05397.12 ORY09155.1 - 0.038 14.3 0.1 0.1 12.9 0.1 1.7 1 0 0 1 1 1 0 Mediator complex subunit 15 adh_short_C2 PF13561.6 ORY09157.1 - 1.1e-37 129.8 0.1 1.8e-37 129.2 0.1 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY09157.1 - 3.5e-34 118.0 0.1 5.4e-34 117.4 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORY09157.1 - 5.9e-10 39.4 2.6 2e-08 34.3 2.6 2.3 1 1 0 1 1 1 1 KR domain AlaDh_PNT_C PF01262.21 ORY09157.1 - 0.002 17.4 0.1 0.0036 16.6 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 ORY09157.1 - 0.01 16.4 0.5 0.031 14.8 0.2 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Epimerase PF01370.21 ORY09157.1 - 0.011 15.3 0.0 0.016 14.6 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 ORY09157.1 - 0.12 11.7 0.1 0.18 11.1 0.1 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Zn_peptidase PF04228.13 ORY09158.1 - 0.13 11.7 0.5 0.18 11.2 0.5 1.1 1 0 0 1 1 1 0 Putative neutral zinc metallopeptidase Helo_like_N PF17111.5 ORY09159.1 - 1.7e-05 24.3 3.3 0.00033 20.1 0.4 2.1 2 0 0 2 2 2 1 Fungal N-terminal domain of STAND proteins NPV_P10 PF05531.12 ORY09159.1 - 8e-05 23.0 5.9 0.2 12.2 0.1 3.1 2 1 1 3 3 3 2 Nucleopolyhedrovirus P10 protein DUF2704 PF10866.8 ORY09159.1 - 0.00059 19.8 0.7 0.0035 17.2 0.3 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2704) Cob_adeno_trans PF01923.18 ORY09159.1 - 0.0011 19.2 3.4 0.036 14.2 0.3 2.1 1 1 1 2 2 2 2 Cobalamin adenosyltransferase SesA PF17107.5 ORY09159.1 - 0.0029 17.8 5.2 0.0043 17.2 1.0 2.3 2 1 0 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases zf-C4H2 PF10146.9 ORY09159.1 - 0.0046 17.3 2.3 0.0081 16.5 2.3 1.4 1 1 0 1 1 1 1 Zinc finger-containing protein Spectrin PF00435.21 ORY09159.1 - 0.019 15.4 5.7 0.21 12.1 0.4 2.6 2 1 0 2 2 2 0 Spectrin repeat COX5A PF02284.16 ORY09159.1 - 0.1 12.6 0.2 0.81 9.7 0.1 2.2 2 0 0 2 2 2 0 Cytochrome c oxidase subunit Va Methyltransf_1N PF02870.15 ORY09159.1 - 0.13 13.0 0.1 26 5.7 0.1 2.4 2 0 0 2 2 2 0 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain HR1 PF02185.16 ORY09159.1 - 0.14 12.3 3.4 4.9 7.4 0.7 2.5 2 0 0 2 2 2 0 Hr1 repeat Baculo_PEP_C PF04513.12 ORY09159.1 - 0.21 11.6 13.0 13 5.8 2.8 3.1 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3450 PF11932.8 ORY09159.1 - 0.28 10.4 5.4 0.2 11.0 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Cor1 PF04803.12 ORY09159.1 - 1.3 9.3 8.5 0.87 9.8 0.7 2.6 2 1 1 3 3 3 0 Cor1/Xlr/Xmr conserved region MitMem_reg PF13012.6 ORY09159.1 - 1.3 9.4 6.6 52 4.3 6.6 2.4 1 1 0 1 1 1 0 Maintenance of mitochondrial structure and function Cauli_AT PF03233.13 ORY09159.1 - 3.1 7.7 6.3 10 6.0 0.2 2.7 2 1 1 3 3 3 0 Aphid transmission protein Syntaxin-6_N PF09177.11 ORY09159.1 - 6.1 7.5 10.5 6.9 7.3 1.7 3.1 1 1 2 3 3 3 0 Syntaxin 6, N-terminal FixQ PF05545.11 ORY09161.1 - 0.2 11.7 2.4 0.4 10.7 2.4 1.5 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ ATPgrasp_YheCD PF14398.6 ORY09162.1 - 0.0093 15.2 0.0 0.012 14.9 0.0 1.1 1 0 0 1 1 1 1 YheC/D like ATP-grasp adh_short_C2 PF13561.6 ORY09163.1 - 1.2e-38 132.9 0.1 2e-38 132.3 0.1 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY09163.1 - 2.6e-35 121.7 0.2 4.4e-35 120.9 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORY09163.1 - 1.4e-05 25.1 0.2 2.5e-05 24.3 0.2 1.3 1 0 0 1 1 1 1 KR domain Pyr_redox PF00070.27 ORY09163.1 - 0.0017 18.9 0.9 0.0029 18.1 0.9 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Epimerase PF01370.21 ORY09163.1 - 0.0021 17.6 0.2 0.0082 15.6 0.1 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 ORY09163.1 - 0.024 14.9 0.1 0.041 14.1 0.1 1.3 1 0 0 1 1 1 0 TrkA-N domain E1-N PF14463.6 ORY09163.1 - 0.031 14.1 0.1 0.054 13.3 0.1 1.4 1 0 0 1 1 1 0 E1 N-terminal domain LUD_dom PF02589.15 ORY09163.1 - 0.038 13.7 0.0 0.062 13.0 0.0 1.4 1 0 0 1 1 1 0 LUD domain Sacchrp_dh_NADP PF03435.18 ORY09163.1 - 0.048 13.9 0.1 0.069 13.4 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 ORY09163.1 - 0.065 13.3 0.0 0.095 12.8 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 ORY09163.1 - 0.13 12.1 0.3 0.19 11.6 0.3 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 ORY09163.1 - 0.3 10.5 0.6 0.48 9.8 0.1 1.5 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase SSF PF00474.17 ORY09164.1 - 7.2e-19 67.9 19.4 7.2e-19 67.9 19.4 1.5 2 0 0 2 2 2 1 Sodium:solute symporter family Bac_luciferase PF00296.20 ORY09165.1 - 6.3e-46 157.2 1.4 9.5e-46 156.7 1.4 1.2 1 0 0 1 1 1 1 Luciferase-like monooxygenase Trehalase PF01204.18 ORY09166.1 - 8.7e-116 387.7 7.3 1.1e-114 384.1 7.3 2.0 1 1 0 1 1 1 1 Trehalase GDE_C PF06202.14 ORY09166.1 - 0.0016 17.4 0.1 0.0029 16.6 0.1 1.3 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase HET PF06985.11 ORY09167.1 - 8.9e-25 87.7 0.0 1.6e-24 86.9 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.16 ORY09168.1 - 4.4e-41 141.0 41.2 4.4e-41 141.0 41.2 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 ORY09168.1 - 0.021 13.1 9.8 0.029 12.7 8.2 2.2 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family p450 PF00067.22 ORY09170.1 - 4.5e-12 45.5 2.1 0.00051 18.9 0.1 4.0 2 1 1 3 3 3 3 Cytochrome P450 FAD_binding_3 PF01494.19 ORY09171.1 - 3e-23 82.7 0.0 4e-23 82.2 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 ORY09171.1 - 1.6e-07 31.2 0.2 1.2e-05 25.1 0.2 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ORY09171.1 - 8.5e-06 25.9 0.1 4.7e-05 23.5 0.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ORY09171.1 - 2e-05 24.0 0.5 0.0012 18.2 0.2 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 ORY09171.1 - 0.0038 16.9 0.1 0.019 14.6 0.1 2.0 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA FAD_binding_2 PF00890.24 ORY09171.1 - 0.0051 15.9 0.2 0.012 14.8 0.1 1.6 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 ORY09171.1 - 0.031 13.0 0.0 0.19 10.4 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.17 ORY09171.1 - 0.035 13.3 0.1 0.09 12.0 0.1 1.6 2 0 0 2 2 2 0 Thi4 family Pyr_redox PF00070.27 ORY09171.1 - 0.055 14.0 0.2 0.37 11.4 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 ORY09171.1 - 0.09 12.1 0.6 0.44 9.9 0.0 2.3 2 1 1 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Citrate_bind PF16114.5 ORY09171.1 - 0.11 12.0 0.2 0.21 11.1 0.0 1.5 2 0 0 2 2 2 0 ATP citrate lyase citrate-binding 3HCDH_N PF02737.18 ORY09171.1 - 0.12 12.2 0.1 0.21 11.5 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 ORY09171.1 - 0.13 12.7 0.1 0.59 10.6 0.1 2.1 1 1 0 1 1 1 0 Putative NAD(P)-binding XdhC_C PF13478.6 ORY09171.1 - 0.14 12.7 0.0 3.6 8.1 0.0 2.6 3 0 0 3 3 3 0 XdhC Rossmann domain UDPG_MGDP_dh_N PF03721.14 ORY09171.1 - 0.14 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Trp_halogenase PF04820.14 ORY09171.1 - 0.2 10.5 1.2 0.28 10.0 0.1 1.8 3 0 0 3 3 3 0 Tryptophan halogenase Shikimate_DH PF01488.20 ORY09171.1 - 0.2 11.7 0.0 0.66 10.0 0.0 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NmrA PF05368.13 ORY09176.1 - 7.8e-21 74.7 0.1 1.2e-20 74.1 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ORY09176.1 - 1.6e-20 73.8 0.0 2.8e-20 73.0 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 ORY09176.1 - 5.3e-08 33.2 0.6 1.3e-07 31.9 0.1 2.0 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 ORY09176.1 - 0.00038 20.5 0.2 0.00086 19.4 0.0 1.6 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase DapB_N PF01113.20 ORY09176.1 - 0.0014 18.8 0.1 0.0034 17.5 0.1 1.6 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Epimerase PF01370.21 ORY09176.1 - 0.0047 16.4 0.0 0.06 12.8 0.0 2.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 ORY09176.1 - 0.027 14.9 0.1 0.053 14.0 0.1 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.10 ORY09176.1 - 0.033 14.1 0.0 0.067 13.1 0.0 1.5 1 0 0 1 1 1 0 KR domain 3Beta_HSD PF01073.19 ORY09176.1 - 0.12 11.3 0.4 0.39 9.7 0.0 2.0 2 1 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Dicty_CAR PF05462.11 ORY09186.1 - 7.1e-15 54.9 9.6 7.1e-15 54.9 9.6 1.7 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor 7tm_2 PF00002.24 ORY09186.1 - 5e-12 45.6 9.2 9.4e-12 44.7 9.2 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Git3 PF11710.8 ORY09186.1 - 8.6e-09 35.5 11.3 8.6e-09 35.5 11.3 1.6 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 Frizzled PF01534.17 ORY09186.1 - 6.8e-05 22.1 11.0 0.00046 19.3 11.0 2.1 1 1 0 1 1 1 1 Frizzled/Smoothened family membrane region STE3 PF02076.15 ORY09186.1 - 0.00028 20.2 7.1 0.00053 19.3 7.1 1.4 1 0 0 1 1 1 1 Pheromone A receptor 7TM_GPCR_Srsx PF10320.9 ORY09186.1 - 0.0017 17.8 3.6 0.0025 17.2 3.6 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx GPR_Gpa2_C PF11970.8 ORY09186.1 - 0.023 14.8 1.4 0.023 14.8 1.4 2.5 3 0 0 3 3 3 0 G protein-coupled glucose receptor regulating Gpa2 C-term Hum_adeno_E3A PF05393.11 ORY09186.1 - 2.6 8.1 0.0 2.6 8.1 0.0 2.8 3 0 0 3 3 3 0 Human adenovirus early E3A glycoprotein HSP70 PF00012.20 ORY09187.1 - 1.5e-77 261.2 0.8 2e-77 260.8 0.8 1.2 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 ORY09187.1 - 2.8e-09 36.3 0.1 4.2e-09 35.7 0.1 1.3 1 0 0 1 1 1 1 MreB/Mbl protein PilM_2 PF11104.8 ORY09187.1 - 0.0055 15.8 0.1 0.76 8.7 0.0 2.3 2 0 0 2 2 2 2 Type IV pilus assembly protein PilM; Hydantoinase_A PF01968.18 ORY09187.1 - 0.035 13.4 0.1 0.085 12.1 0.1 1.6 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase Cwf_Cwc_15 PF04889.12 ORY09187.1 - 0.079 12.7 2.3 0.14 11.8 2.3 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Rrp40_N PF18311.1 ORY09188.1 - 1.5e-18 66.4 0.4 5.6e-18 64.6 0.6 1.9 2 0 0 2 2 2 1 Exosome complex exonuclease Rrp40 N-terminal domain KH_6 PF15985.5 ORY09188.1 - 8e-14 51.7 0.8 1.4e-13 51.0 0.8 1.4 1 0 0 1 1 1 1 KH domain tRNA-synt_2 PF00152.20 ORY09190.1 - 7.1e-72 242.1 0.0 9.3e-72 241.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 ORY09190.1 - 0.00017 21.5 0.1 0.00028 20.8 0.1 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 ORY09190.1 - 0.066 12.7 0.1 2.8 7.3 0.1 2.3 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) Raptor_N PF14538.6 ORY09191.1 - 1.9e-65 219.3 0.0 3.6e-65 218.4 0.0 1.5 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain ANAPC4_WD40 PF12894.7 ORY09191.1 - 1.2e-05 25.5 0.1 8.5 6.8 0.0 4.6 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 ORY09191.1 - 1.7e-05 25.5 8.4 1.9 9.5 0.1 6.1 6 1 0 6 6 6 2 WD domain, G-beta repeat BBS2_Mid PF14783.6 ORY09191.1 - 0.00036 20.5 0.2 0.019 15.0 0.1 2.7 1 1 1 2 2 2 1 Ciliary BBSome complex subunit 2, middle region Atx10homo_assoc PF09759.9 ORY09191.1 - 0.02 14.9 0.1 0.043 13.8 0.1 1.5 1 0 0 1 1 1 0 Spinocerebellar ataxia type 10 protein domain Cnd1 PF12717.7 ORY09191.1 - 0.067 13.2 0.1 0.52 10.3 0.1 2.2 1 1 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 ORY09191.1 - 0.45 10.9 4.4 53 4.5 0.0 4.5 5 0 0 5 5 5 0 HEAT repeat Kelch_5 PF13854.6 ORY09193.1 - 7.8e-30 102.4 7.2 6.1e-09 35.7 0.1 6.5 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 ORY09193.1 - 4.2e-28 96.7 8.5 2e-10 40.5 0.8 6.5 5 1 1 6 6 6 5 Kelch motif Kelch_3 PF13415.6 ORY09193.1 - 5.1e-28 96.8 18.0 3.1e-05 24.2 0.3 6.2 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_4 PF13418.6 ORY09193.1 - 5.6e-27 93.5 15.3 6.1e-05 22.9 1.2 6.7 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_1 PF01344.25 ORY09193.1 - 6.9e-24 83.2 6.8 2.4e-10 39.8 0.7 6.3 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.15 ORY09193.1 - 4.6e-18 64.4 9.2 2.2e-09 36.9 0.8 5.6 5 0 0 5 5 5 4 Kelch motif Laminin_II PF06009.12 ORY09193.1 - 0.0071 16.4 8.5 0.0071 16.4 8.5 7.6 4 2 4 8 8 8 1 Laminin Domain II Fib_alpha PF08702.10 ORY09193.1 - 0.0086 16.3 6.6 0.0086 16.3 6.6 6.6 3 2 5 8 8 8 1 Fibrinogen alpha/beta chain family RAG2 PF03089.14 ORY09193.1 - 0.066 12.2 0.0 1.1 8.1 0.0 2.7 3 0 0 3 3 3 0 Recombination activating protein 2 RPW8 PF05659.11 ORY09193.1 - 8.3 6.1 22.0 0.5 10.1 1.6 4.8 3 2 3 6 6 6 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Ank_2 PF12796.7 ORY09194.1 - 9e-40 135.2 0.0 5.5e-12 46.1 0.0 8.6 7 2 2 9 9 9 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY09194.1 - 7e-29 99.8 0.0 2.1e-05 25.0 0.0 9.9 10 0 0 10 10 10 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 ORY09194.1 - 1.7e-28 98.3 2.9 0.0013 19.0 0.1 9.9 8 1 1 9 9 9 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY09194.1 - 1.7e-25 86.3 2.9 0.00055 20.2 0.0 11.8 13 0 0 13 13 13 3 Ankyrin repeat Ank PF00023.30 ORY09194.1 - 5.2e-23 80.4 7.2 0.0018 18.6 0.1 10.1 10 0 0 10 10 10 4 Ankyrin repeat B12-binding_2 PF02607.17 ORY09194.1 - 0.41 11.1 2.0 12 6.4 0.0 3.6 4 0 0 4 4 4 0 B12 binding domain TnpV PF14198.6 ORY09194.1 - 1.9 8.5 5.5 1.1 9.2 0.1 2.7 2 0 0 2 2 2 0 Transposon-encoded protein TnpV DUF840 PF05801.11 ORY09196.1 - 0.063 13.3 0.1 0.23 11.5 0.3 1.7 2 0 0 2 2 2 0 Lagovirus protein of unknown function (DUF840) Sod_Cu PF00080.20 ORY09197.1 - 1.3e-10 41.6 0.0 3.1e-10 40.4 0.0 1.5 2 0 0 2 2 2 1 Copper/zinc superoxide dismutase (SODC) Carcinustatin PF08261.12 ORY09197.1 - 1.9 9.4 4.0 6.4 7.8 0.9 2.8 2 0 0 2 2 2 0 Carcinustatin peptide AMP-binding PF00501.28 ORY09198.1 - 3.2e-73 246.7 0.1 1.1e-72 245.0 0.0 1.8 2 0 0 2 2 2 1 AMP-binding enzyme NAD_binding_4 PF07993.12 ORY09198.1 - 2.8e-61 207.0 0.0 1.3e-60 204.8 0.0 2.0 2 0 0 2 2 2 1 Male sterility protein adh_short PF00106.25 ORY09198.1 - 1.1e-48 165.3 1.2 1.9e-48 164.5 1.2 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY09198.1 - 5.7e-38 130.8 1.5 7.6e-38 130.4 0.7 1.6 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY09198.1 - 6.3e-19 68.6 0.8 2.1e-16 60.4 0.5 2.4 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 ORY09198.1 - 1.1e-14 54.5 0.0 5.6e-08 32.5 0.0 3.2 3 2 0 3 3 3 2 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 ORY09198.1 - 5.1e-13 49.2 0.0 1.3e-12 47.8 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Polysacc_synt_2 PF02719.15 ORY09198.1 - 5.8e-08 32.2 0.3 1.1e-05 24.7 0.2 3.1 3 0 0 3 3 3 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 ORY09198.1 - 1.4e-07 30.8 0.3 0.00051 19.1 0.0 3.1 2 1 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 ORY09198.1 - 2.6e-07 30.7 0.4 2.3e-06 27.6 0.5 2.3 2 0 0 2 2 2 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 ORY09198.1 - 3.1e-06 26.5 0.6 0.0055 15.9 0.0 2.8 3 0 0 3 3 3 2 RmlD substrate binding domain ApbA PF02558.16 ORY09198.1 - 0.0046 16.6 0.1 0.01 15.5 0.1 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA AMP-binding_C PF13193.6 ORY09198.1 - 0.0077 17.2 0.1 0.0077 17.2 0.1 3.4 3 1 0 3 3 3 1 AMP-binding enzyme C-terminal domain GDP_Man_Dehyd PF16363.5 ORY09198.1 - 0.014 14.8 0.0 1.6 8.0 0.0 2.7 3 0 0 3 3 3 0 GDP-mannose 4,6 dehydratase RimM PF01782.18 ORY09198.1 - 0.02 15.1 0.2 0.051 13.8 0.2 1.6 1 0 0 1 1 1 0 RimM N-terminal domain DFP PF04127.15 ORY09198.1 - 0.042 13.7 0.4 0.19 11.6 0.6 1.9 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein PALP PF00291.25 ORY09198.1 - 0.13 11.6 1.2 0.29 10.5 1.2 1.5 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme BetaGal_dom4_5 PF13364.6 ORY09199.1 - 2e-26 92.8 0.0 2.4e-26 92.5 0.0 1.1 1 0 0 1 1 1 1 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.6 ORY09200.1 - 1.2e-17 63.2 0.0 3.5e-17 61.7 0.0 1.7 2 0 0 2 2 2 1 Beta-galactosidase, domain 3 BetaGal_dom2 PF10435.9 ORY09200.1 - 0.00025 20.9 0.0 0.00039 20.3 0.0 1.3 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 Na_Ca_ex PF01699.24 ORY09201.1 - 2.7e-24 85.9 24.6 3.8e-15 56.2 9.7 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Ion_trans PF00520.31 ORY09201.1 - 4.9 6.3 10.1 2 7.6 0.1 3.1 3 0 0 3 3 3 0 Ion transport protein Pro-kuma_activ PF09286.11 ORY09202.1 - 1.2e-42 145.6 0.0 1.9e-42 144.9 0.0 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 ORY09202.1 - 6.8e-07 28.8 0.1 1.3e-06 27.9 0.1 1.4 1 0 0 1 1 1 1 Subtilase family CUT PF02376.15 ORY09202.1 - 0.023 14.8 0.0 0.095 12.9 0.0 1.9 2 0 0 2 2 2 0 CUT domain SGL PF08450.12 ORY09203.1 - 4.2e-68 229.6 0.4 7.4e-68 228.8 0.1 1.5 2 0 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region Phytase-like PF13449.6 ORY09203.1 - 0.094 12.6 0.0 0.36 10.7 0.0 1.8 1 1 1 2 2 2 0 Esterase-like activity of phytase DUF1746 PF08508.10 ORY09204.1 - 1.7e-22 80.0 0.0 2.3e-22 79.5 0.0 1.2 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1746) PHC2_SAM_assoc PF16616.5 ORY09204.1 - 0.26 12.1 2.3 0.17 12.7 0.4 1.6 2 0 0 2 2 2 0 Unstructured region on Polyhomeotic-like protein 1 and 2 HIG_1_N PF04588.13 ORY09205.1 - 5.2e-19 68.2 0.1 7.5e-19 67.7 0.1 1.2 1 0 0 1 1 1 1 Hypoxia induced protein conserved region bZIP_2 PF07716.15 ORY09210.1 - 0.0025 17.8 9.1 0.0048 17.0 9.1 1.5 1 0 0 1 1 1 1 Basic region leucine zipper RNA_pol_Rpc4 PF05132.14 ORY09212.1 - 0.092 13.2 2.4 0.093 13.2 2.4 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 RPN2_C PF18004.1 ORY09212.1 - 1.6 8.6 12.8 2.3 8.1 12.8 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain MAP17 PF15807.5 ORY09212.1 - 1.7 8.9 6.2 2.3 8.4 6.2 1.2 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Presenilin PF01080.17 ORY09212.1 - 1.8 7.2 4.9 2.1 7.1 4.9 1.1 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.12 ORY09212.1 - 1.8 8.3 9.0 2.3 8.0 9.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Connexin PF00029.19 ORY09212.1 - 2.9 7.6 5.7 3.6 7.3 5.7 1.1 1 0 0 1 1 1 0 Connexin CDC45 PF02724.14 ORY09212.1 - 5 5.3 9.9 6.1 5.0 9.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Eapp_C PF10238.9 ORY09212.1 - 8 6.5 7.3 12 6.0 7.3 1.2 1 0 0 1 1 1 0 E2F-associated phosphoprotein FAA_hydrolase PF01557.18 ORY09214.1 - 1.2e-59 201.7 0.0 1.9e-59 201.0 0.0 1.3 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Hydrolase_4 PF12146.8 ORY09214.1 - 4e-17 62.3 0.0 8.9e-17 61.1 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ORY09214.1 - 2.4e-16 61.0 0.0 6.2e-16 59.7 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ORY09214.1 - 2.6e-16 60.1 0.0 1.7e-12 47.6 0.0 2.3 1 1 0 2 2 2 2 alpha/beta hydrolase fold Amidohydro_1 PF01979.20 ORY09214.1 - 7.9e-13 48.4 0.1 1.3e-12 47.7 0.1 1.3 1 0 0 1 1 1 1 Amidohydrolase family Ser_hydrolase PF06821.13 ORY09214.1 - 8.6e-05 22.5 0.0 0.00054 19.9 0.0 2.1 2 0 0 2 2 2 1 Serine hydrolase Ndr PF03096.14 ORY09214.1 - 0.0015 17.3 0.0 0.0026 16.5 0.0 1.3 1 0 0 1 1 1 1 Ndr family Amidohydro_3 PF07969.11 ORY09214.1 - 0.0016 18.0 1.0 1.2 8.5 0.3 3.2 2 1 0 2 2 2 2 Amidohydrolase family PGAP1 PF07819.13 ORY09214.1 - 0.04 13.6 0.0 5.3 6.7 0.0 2.5 2 0 0 2 2 2 0 PGAP1-like protein HdeA PF06411.11 ORY09214.1 - 0.051 13.8 0.0 0.1 12.8 0.0 1.4 1 0 0 1 1 1 0 HdeA/HdeB family Palm_thioest PF02089.15 ORY09214.1 - 0.063 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Palmitoyl protein thioesterase CN_hydrolase PF00795.22 ORY09217.1 - 1.7e-34 119.3 0.0 1.5e-33 116.3 0.0 2.1 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase Asp_Glu_race PF01177.22 ORY09217.1 - 4.9e-08 33.1 0.0 1.3e-07 31.8 0.0 1.7 2 0 0 2 2 2 1 Asp/Glu/Hydantoin racemase DUF3552 PF12072.8 ORY09218.1 - 0.019 14.4 13.8 0.024 14.1 13.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Ferritin_2 PF13668.6 ORY09219.1 - 8.8e-42 142.5 2.9 1.3e-41 142.0 2.9 1.2 1 0 0 1 1 1 1 Ferritin-like domain SnoaL_2 PF12680.7 ORY09222.1 - 1.5e-05 25.6 0.0 1.9e-05 25.2 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 ORY09222.1 - 0.00013 21.8 0.0 0.00017 21.4 0.0 1.3 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase Aldo_ket_red PF00248.21 ORY09223.1 - 1.2e-53 182.2 0.0 1.4e-53 182.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Transp_cyt_pur PF02133.15 ORY09224.1 - 1.4e-91 307.5 39.3 1.7e-91 307.2 39.3 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Ribonuc_L-PSP PF01042.21 ORY09225.1 - 1.7e-37 128.1 0.0 1.9e-37 127.9 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Acetyltransf_10 PF13673.7 ORY09226.1 - 1.1e-07 31.9 0.0 1.9e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORY09226.1 - 8.2e-07 29.3 0.0 1.3e-06 28.7 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ORY09226.1 - 2.1e-06 28.1 0.0 3.3e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 ORY09226.1 - 0.069 13.2 0.0 0.29 11.2 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain DUF3425 PF11905.8 ORY09227.1 - 2.5e-21 75.9 1.1 4.6e-21 75.1 1.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) WSD PF15613.6 ORY09227.1 - 0.028 14.9 2.2 6.9 7.2 1.0 2.7 1 1 1 2 2 2 0 Williams-Beuren syndrome DDT (WSD), D-TOX E motif bZIP_1 PF00170.21 ORY09227.1 - 0.094 12.8 10.3 0.07 13.2 5.8 2.2 2 0 0 2 2 2 0 bZIP transcription factor ScsC_N PF18312.1 ORY09227.1 - 0.18 11.6 2.2 0.24 11.2 0.5 2.1 2 0 0 2 2 2 0 Copper resistance protein ScsC N-terminal domain AtuA PF07287.11 ORY09228.1 - 4.6e-21 74.9 0.0 1.5e-10 40.4 0.0 2.1 2 0 0 2 2 2 2 Acyclic terpene utilisation family protein AtuA ABM PF03992.16 ORY09229.1 - 1.5e-14 53.9 0.0 4.6e-09 36.3 0.0 2.3 2 1 0 2 2 2 2 Antibiotic biosynthesis monooxygenase TRI12 PF06609.13 ORY09230.1 - 1.3e-78 264.9 21.3 1.8e-78 264.5 21.3 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 ORY09230.1 - 5.5e-20 71.6 47.4 5.5e-20 71.6 47.4 3.2 1 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY09230.1 - 2.6e-08 33.2 6.6 2.6e-08 33.2 6.6 2.8 1 1 2 3 3 3 1 Sugar (and other) transporter adh_short_C2 PF13561.6 ORY09231.1 - 1.7e-67 227.4 2.9 2e-67 227.1 2.9 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY09231.1 - 8.2e-51 172.2 1.9 1e-50 171.9 1.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORY09231.1 - 9.5e-12 45.2 0.9 1.6e-11 44.5 0.9 1.3 1 0 0 1 1 1 1 KR domain AMP-binding PF00501.28 ORY09232.1 - 4.1e-77 259.6 0.0 5.2e-77 259.2 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORY09232.1 - 3.3e-14 53.6 0.1 5.8e-14 52.8 0.1 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Atu4866 PF11512.8 ORY09232.1 - 0.17 12.2 0.1 1.8 9.0 0.0 2.2 2 0 0 2 2 2 0 Agrobacterium tumefaciens protein Atu4866 ECH_1 PF00378.20 ORY09233.1 - 2e-43 148.5 0.0 2.4e-43 148.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ORY09233.1 - 1.6e-18 67.3 0.1 5.9e-17 62.2 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 ORY09233.1 - 0.051 13.5 0.0 5.5 6.9 0.0 2.2 2 0 0 2 2 2 0 Peptidase family S49 Plectin PF00681.20 ORY09233.1 - 0.063 13.2 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 Plectin repeat ECH_1 PF00378.20 ORY09234.1 - 2e-60 204.2 0.0 2.6e-60 203.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ORY09234.1 - 2.6e-25 89.6 0.0 4.2e-25 88.9 0.0 1.3 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase UL42 PF17638.2 ORY09234.1 - 0.16 11.9 0.8 0.27 11.2 0.8 1.3 1 0 0 1 1 1 0 HCMV UL42 MaoC_dehydratas PF01575.19 ORY09235.1 - 1.1e-22 79.9 0.0 1.7e-22 79.2 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 ORY09235.1 - 0.0003 20.9 0.0 0.015 15.5 0.0 2.4 2 1 0 2 2 2 1 N-terminal half of MaoC dehydratase BppU_N PF10651.9 ORY09235.1 - 0.047 13.4 0.0 0.074 12.7 0.0 1.2 1 0 0 1 1 1 0 BppU N-terminal domain DUF3280 PF11684.8 ORY09235.1 - 0.23 11.9 0.0 0.4 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2380) AtuA PF07287.11 ORY09236.1 - 8.8e-126 419.3 0.0 1.1e-125 419.0 0.0 1.1 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA AMP-binding PF00501.28 ORY09237.1 - 4.3e-68 229.8 0.0 5.4e-68 229.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Fringe PF02434.16 ORY09238.1 - 3.7e-08 33.1 0.1 3.6e-07 29.9 0.1 2.0 1 1 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 ORY09238.1 - 0.021 14.7 0.0 0.23 11.2 0.0 2.0 1 1 1 2 2 2 0 Galactosyltransferase PAN_3 PF08277.12 ORY09238.1 - 0.11 12.3 0.4 0.23 11.3 0.4 1.4 1 0 0 1 1 1 0 PAN-like domain Glyco_transf_8 PF01501.20 ORY09239.1 - 0.00019 21.1 0.3 0.0011 18.6 0.3 2.2 1 1 0 1 1 1 1 Glycosyl transferase family 8 DUF4360 PF14273.6 ORY09240.1 - 0.00039 20.4 0.1 0.0045 16.9 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4360) DUF108 PF01958.18 ORY09241.1 - 0.11 12.9 0.5 0.16 12.4 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF108 Ion_trans_2 PF07885.16 ORY09242.1 - 8e-25 86.6 25.2 1.2e-16 60.4 5.8 3.4 3 0 0 3 3 3 2 Ion channel SieB PF14163.6 ORY09242.1 - 0.34 10.4 0.0 0.34 10.4 0.0 2.2 3 0 0 3 3 3 0 Super-infection exclusion protein B DEAD PF00270.29 ORY09244.1 - 4.7e-45 153.5 0.0 8.8e-45 152.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY09244.1 - 3.6e-28 98.1 0.0 1.1e-25 90.1 0.0 2.6 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 ORY09244.1 - 0.0014 18.7 0.0 0.003 17.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 ORY09244.1 - 0.0015 17.4 0.3 0.041 12.7 0.0 2.7 3 0 0 3 3 3 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 RRM_1 PF00076.22 ORY09246.1 - 2.7e-14 52.7 0.0 7.9e-14 51.2 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MoaE PF02391.17 ORY09247.1 - 1.1e-35 122.3 0.0 1.4e-35 122.0 0.0 1.1 1 0 0 1 1 1 1 MoaE protein HTH_23 PF13384.6 ORY09250.1 - 0.028 14.2 0.0 0.24 11.2 0.0 2.3 2 1 0 2 2 2 0 Homeodomain-like domain MFS_1 PF07690.16 ORY09251.1 - 1.9e-22 79.7 37.4 1.9e-22 79.7 37.4 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF3433 PF11915.8 ORY09252.1 - 3.8e-32 110.6 16.5 1.8e-21 76.4 2.9 3.3 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) Pro_isomerase PF00160.21 ORY09267.1 - 4e-48 163.7 0.2 5.3e-48 163.3 0.2 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DEAD PF00270.29 ORY09268.1 - 1.9e-48 164.5 0.0 5.1e-48 163.2 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY09268.1 - 4.1e-32 110.8 0.0 8.7e-32 109.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY09268.1 - 0.033 14.2 0.0 0.062 13.3 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit CMS1 PF14617.6 ORY09268.1 - 0.13 11.6 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit ADK PF00406.22 ORY09270.1 - 4.5e-47 159.9 0.0 5.6e-47 159.6 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 ORY09270.1 - 6.6e-38 130.2 0.0 1e-37 129.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 ORY09270.1 - 1.9e-09 38.2 0.0 2.6e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 ORY09270.1 - 1.8e-05 24.5 0.8 0.018 14.7 0.0 2.2 2 0 0 2 2 2 2 Thymidylate kinase AAA_33 PF13671.6 ORY09270.1 - 0.0005 20.3 0.1 0.0035 17.5 0.1 2.1 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 ORY09270.1 - 0.019 14.3 0.1 0.045 13.0 0.1 1.7 1 1 0 1 1 1 0 Zeta toxin Ploopntkinase3 PF18751.1 ORY09270.1 - 0.072 13.0 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 AAA_28 PF13521.6 ORY09270.1 - 0.1 12.8 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain DNA_pol_E_B PF04042.16 ORY09275.1 - 3.3e-43 147.5 0.0 4.4e-43 147.1 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 ORY09275.1 - 7.6e-40 136.0 0.0 1.2e-39 135.4 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain GMC_oxred_N PF00732.19 ORY09277.1 - 6e-49 167.0 0.0 8.7e-49 166.5 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 ORY09277.1 - 2e-34 119.2 0.0 3.1e-34 118.6 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Thi4 PF01946.17 ORY09277.1 - 0.003 16.8 0.1 0.0053 16.0 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 ORY09277.1 - 0.01 14.9 0.5 0.017 14.2 0.5 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_2 PF00890.24 ORY09277.1 - 0.015 14.4 1.3 0.068 12.2 1.4 1.9 2 0 0 2 2 2 0 FAD binding domain NAD_binding_8 PF13450.6 ORY09277.1 - 0.021 15.0 0.5 0.069 13.4 0.5 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ORY09277.1 - 0.048 13.2 0.1 0.1 12.2 0.1 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ORY09277.1 - 0.063 12.5 0.0 0.14 11.3 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Cytochrom_C1 PF02167.15 ORY09279.1 - 5.1e-94 314.1 0.0 6.3e-94 313.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 ORY09279.1 - 0.016 15.5 0.0 0.04 14.2 0.0 1.7 1 0 0 1 1 1 0 Cytochrome C oxidase, cbb3-type, subunit III MFS_1 PF07690.16 ORY09280.1 - 7.8e-33 113.9 28.6 7.8e-33 113.9 28.6 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY09280.1 - 8.5e-11 41.4 9.2 8.5e-11 41.4 9.2 2.2 3 0 0 3 3 3 1 Sugar (and other) transporter PTR2 PF00854.21 ORY09280.1 - 1.3e-06 27.5 0.1 1.3e-06 27.5 0.1 1.6 2 0 0 2 2 2 1 POT family DUF3543 PF12063.8 ORY09281.1 - 2.3e-85 286.0 0.0 3.6e-85 285.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase PF00069.25 ORY09281.1 - 4.5e-59 200.0 0.0 8.3e-59 199.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY09281.1 - 2.6e-41 141.6 0.0 5.2e-41 140.6 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Peptidase_M1 PF01433.20 ORY09285.1 - 5.1e-86 287.7 0.3 8.4e-86 287.0 0.3 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 ORY09285.1 - 7.6e-82 275.4 0.2 3.8e-81 273.1 0.3 2.0 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 ORY09285.1 - 1.8e-52 178.2 1.4 6e-52 176.5 1.2 1.9 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain DUF2808 PF10989.8 ORY09285.1 - 0.0011 19.0 0.0 0.0022 18.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2808) ABC2_membrane PF01061.24 ORY09288.1 - 2.7e-86 288.3 60.6 2.6e-45 154.5 15.0 2.7 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 ORY09288.1 - 4.1e-37 127.8 0.0 2.3e-18 67.0 0.0 2.7 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 ORY09288.1 - 3.7e-29 100.5 6.5 1.8e-25 88.7 0.1 3.1 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.6 ORY09288.1 - 9.7e-18 64.6 1.8 9.7e-18 64.6 1.8 2.6 2 1 0 2 2 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 ORY09288.1 - 9.5e-08 32.6 0.1 0.0024 18.3 0.1 2.6 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 ORY09288.1 - 9.8e-06 25.6 0.2 0.00036 20.5 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase ABC2_membrane_3 PF12698.7 ORY09288.1 - 1.1e-05 24.7 10.2 1.1e-05 24.7 10.2 2.8 3 0 0 3 3 3 1 ABC-2 family transporter protein AAA_21 PF13304.6 ORY09288.1 - 1.2e-05 25.3 2.0 0.12 12.2 0.1 4.1 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 ORY09288.1 - 2.2e-05 24.5 0.1 0.013 15.6 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_29 PF13555.6 ORY09288.1 - 6.3e-05 22.6 0.3 0.35 10.7 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 ORY09288.1 - 8.7e-05 22.8 0.0 0.15 12.4 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 ORY09288.1 - 0.00016 22.2 0.0 0.02 15.5 0.0 2.9 3 0 0 3 3 2 1 AAA domain cobW PF02492.19 ORY09288.1 - 0.0016 18.0 0.1 0.017 14.7 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 ORY09288.1 - 0.0018 18.5 0.0 0.069 13.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 ORY09288.1 - 0.0033 17.4 0.1 0.44 10.4 0.1 2.4 2 0 0 2 2 2 1 NACHT domain AAA_28 PF13521.6 ORY09288.1 - 0.0044 17.3 2.1 0.0071 16.6 0.1 2.4 3 0 0 3 3 2 1 AAA domain AAA_30 PF13604.6 ORY09288.1 - 0.0047 16.7 0.4 1 9.1 0.3 2.3 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.18 ORY09288.1 - 0.009 15.4 0.3 3.5 6.9 0.1 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family SMC_N PF02463.19 ORY09288.1 - 0.019 14.4 0.6 1.2 8.5 0.0 3.3 3 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 ORY09288.1 - 0.025 14.1 0.1 0.63 9.6 0.1 2.5 2 0 0 2 2 2 0 AAA domain Septin PF00735.18 ORY09288.1 - 0.027 13.8 0.0 0.25 10.6 0.1 2.3 2 0 0 2 2 2 0 Septin NB-ARC PF00931.22 ORY09288.1 - 0.028 13.6 0.2 1.3 8.1 0.1 2.4 2 0 0 2 2 2 0 NB-ARC domain AAA_24 PF13479.6 ORY09288.1 - 0.031 14.0 0.0 0.48 10.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 ORY09288.1 - 0.062 12.6 0.2 0.43 9.8 0.2 2.1 2 0 0 2 2 2 0 Zeta toxin AAA_17 PF13207.6 ORY09288.1 - 0.068 13.6 0.1 7.9 6.9 0.1 2.6 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 ORY09288.1 - 0.11 12.5 0.2 1.7 8.7 0.2 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Dynamin_N PF00350.23 ORY09288.1 - 0.12 12.4 2.2 1.3 9.1 0.2 3.0 3 0 0 3 3 3 0 Dynamin family Ploopntkinase3 PF18751.1 ORY09288.1 - 0.13 12.1 0.0 14 5.5 0.0 2.3 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 FeoB_N PF02421.18 ORY09288.1 - 0.19 11.2 0.1 1.1 8.7 0.1 2.0 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_23 PF13476.6 ORY09288.1 - 0.92 10.0 3.9 2.6 8.5 0.0 3.3 4 0 0 4 4 4 0 AAA domain MFS_1 PF07690.16 ORY09290.1 - 3.5e-48 164.3 35.1 3.5e-48 164.3 35.1 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY09290.1 - 8.8e-12 44.6 9.1 8.8e-12 44.6 9.1 2.3 2 1 0 3 3 3 1 Sugar (and other) transporter MFS_4 PF06779.14 ORY09290.1 - 1.2e-05 24.8 6.1 1.2e-05 24.8 6.1 2.4 3 0 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB SNF2_N PF00176.23 ORY09292.1 - 2.9e-66 223.6 0.1 4.3e-66 223.0 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.11 ORY09292.1 - 6.4e-17 61.3 0.0 1.5e-16 60.1 0.0 1.6 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.31 ORY09292.1 - 2.1e-15 57.0 0.0 1.4e-14 54.3 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.6 ORY09292.1 - 2.7e-10 39.9 9.2 2.7e-10 39.9 9.2 1.6 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 ORY09292.1 - 3.6e-09 36.3 12.9 6.5e-09 35.5 12.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORY09292.1 - 1.5e-08 34.4 12.8 2.6e-08 33.6 12.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORY09292.1 - 1.9e-08 34.5 11.8 3.6e-08 33.6 11.8 1.5 1 0 0 1 1 1 1 Ring finger domain ResIII PF04851.15 ORY09292.1 - 7.5e-08 32.6 0.0 1.8e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-RING_UBOX PF13445.6 ORY09292.1 - 1.6e-07 31.2 9.9 3.2e-07 30.3 9.9 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 ORY09292.1 - 8.2e-07 28.9 9.4 1.4e-06 28.1 9.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 ORY09292.1 - 1e-06 28.7 10.9 1.8e-06 28.0 10.9 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 ORY09292.1 - 1.7e-05 25.0 6.7 4e-05 23.8 6.7 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 ORY09292.1 - 3.2e-05 23.7 8.9 6.5e-05 22.7 8.9 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 ORY09292.1 - 0.00085 19.2 4.5 0.0018 18.1 4.5 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-Nse PF11789.8 ORY09292.1 - 0.0072 16.1 8.6 0.017 14.9 8.6 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-ANAPC11 PF12861.7 ORY09292.1 - 0.03 14.4 5.3 0.082 13.0 4.9 1.8 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger U-box PF04564.15 ORY09292.1 - 0.055 13.7 0.2 0.27 11.4 0.2 2.2 1 0 0 1 1 1 0 U-box domain zf-RING_4 PF14570.6 ORY09292.1 - 0.064 13.1 7.7 0.14 12.0 7.7 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.5 ORY09292.1 - 0.066 13.0 6.4 0.18 11.6 6.4 1.8 1 0 0 1 1 1 0 RING-like zinc finger HDA2-3 PF11496.8 ORY09292.1 - 0.12 11.5 0.2 0.79 8.8 0.0 2.4 2 0 0 2 2 2 0 Class II histone deacetylase complex subunits 2 and 3 zinc-ribbons_6 PF07191.12 ORY09292.1 - 0.22 11.5 6.0 0.4 10.7 6.0 1.4 1 0 0 1 1 1 0 zinc-ribbons Rtf2 PF04641.12 ORY09292.1 - 1.4 8.2 6.4 2.4 7.5 1.4 2.3 2 0 0 2 2 2 0 Rtf2 RING-finger zf-LITAF-like PF10601.9 ORY09292.1 - 1.5 9.1 8.0 4.5 7.6 8.0 1.8 1 1 0 1 1 1 0 LITAF-like zinc ribbon domain zf-RING_10 PF16685.5 ORY09292.1 - 1.8 8.8 6.1 4.1 7.6 6.1 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 hDGE_amylase PF14701.6 ORY09293.1 - 2.7e-177 590.3 0.0 3.5e-177 589.9 0.0 1.1 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain GDE_C PF06202.14 ORY09293.1 - 2.9e-121 405.0 0.1 5.4e-121 404.1 0.1 1.4 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.6 ORY09293.1 - 2e-87 293.1 0.0 3.6e-87 292.2 0.0 1.5 1 0 0 1 1 1 1 Central domain of human glycogen debranching enzyme hGDE_N PF14699.6 ORY09293.1 - 8.9e-28 96.3 0.1 2.5e-27 94.8 0.1 1.8 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.24 ORY09293.1 - 0.00033 20.4 0.1 0.0011 18.6 0.1 1.8 2 0 0 2 2 2 1 Alpha amylase, catalytic domain RhoGAP PF00620.27 ORY09294.1 - 8.9e-30 103.5 0.0 1.4e-29 102.9 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain DUF1952 PF09189.10 ORY09294.1 - 0.096 12.5 0.0 0.26 11.1 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1952) Prenyltrans PF00432.21 ORY09295.1 - 6.4e-56 185.8 9.3 3.9e-11 42.5 0.0 6.1 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 ORY09295.1 - 0.0046 16.1 0.0 4.1 6.4 0.0 3.5 2 1 2 4 4 4 2 Squalene-hopene cyclase N-terminal domain SQHop_cyclase_C PF13243.6 ORY09295.1 - 0.0061 15.7 0.2 0.031 13.4 0.1 2.1 1 1 1 2 2 2 1 Squalene-hopene cyclase C-terminal domain Far-17a_AIG1 PF04750.14 ORY09297.1 - 1.9e-42 144.9 8.9 2.2e-42 144.7 8.9 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein Glyco_hydro_3_C PF01915.22 ORY09298.1 - 1.3e-55 188.5 0.0 5.4e-55 186.5 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 ORY09298.1 - 7.5e-51 173.4 0.0 1.2e-50 172.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 ORY09298.1 - 1.3e-17 63.6 0.1 3.5e-17 62.3 0.1 1.8 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 ORY09298.1 - 5.9e-07 29.4 0.0 1.2e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 PA14 domain Fungal_trans_2 PF11951.8 ORY09299.1 - 1e-09 37.7 2.5 2.7e-08 33.0 1.4 2.8 2 1 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY09299.1 - 3.8e-08 33.3 8.9 3.8e-08 33.3 8.9 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_N PF08240.12 ORY09300.1 - 2e-23 82.3 1.9 2e-23 82.3 1.9 2.2 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORY09300.1 - 2.6e-22 79.2 1.3 5.4e-22 78.2 1.3 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ORY09300.1 - 0.002 19.2 0.3 0.0042 18.1 0.3 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase COesterase PF00135.28 ORY09302.1 - 1.5e-76 258.3 0.0 1.3e-67 228.8 0.0 2.1 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 ORY09302.1 - 3.9e-11 43.2 0.1 3.9e-11 43.2 0.1 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold AltA1 PF16541.5 ORY09303.1 - 3.7e-12 47.1 0.8 6.1e-12 46.4 0.5 1.6 1 1 0 1 1 1 1 Alternaria alternata allergen 1 p450 PF00067.22 ORY09304.1 - 9.4e-56 189.5 0.2 1.9e-55 188.5 0.2 1.4 1 1 0 1 1 1 1 Cytochrome P450 PCI PF01399.27 ORY09305.1 - 1.5e-12 48.0 0.0 7.2e-12 45.7 0.0 2.1 2 0 0 2 2 2 1 PCI domain eIF3m_C_helix PF18005.1 ORY09305.1 - 2.6e-12 46.2 1.0 5.1e-12 45.3 1.0 1.5 1 0 0 1 1 1 1 eIF3 subunit M, C-terminal helix TPR_14 PF13428.6 ORY09305.1 - 0.03 15.1 2.4 0.064 14.1 0.6 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF1153 PF06627.11 ORY09306.1 - 0.097 12.8 0.3 9.3 6.5 0.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1153) ADH_N PF08240.12 ORY09307.1 - 5e-20 71.4 4.3 7.9e-20 70.8 4.3 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORY09307.1 - 4.4e-14 52.6 0.0 7.7e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 ORY09307.1 - 2.1e-05 23.9 0.0 3.7e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 ORY09307.1 - 0.00031 20.1 0.0 0.00051 19.4 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.6 ORY09307.1 - 0.0056 17.7 0.0 0.011 16.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase MFS_1 PF07690.16 ORY09308.1 - 1.6e-30 106.3 38.3 1.6e-30 106.3 38.3 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily BNIP3 PF06553.12 ORY09308.1 - 0.059 13.0 0.0 0.095 12.4 0.0 1.2 1 0 0 1 1 1 0 BNIP3 EzrA PF06160.12 ORY09310.1 - 0.16 10.2 0.0 0.19 9.9 0.0 1.0 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA PBP PF01161.20 ORY09311.1 - 7.8e-08 32.7 0.2 9.5e-08 32.4 0.2 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein G3P_antiterm PF04309.12 ORY09311.1 - 0.039 13.4 0.1 0.056 12.9 0.1 1.2 1 0 0 1 1 1 0 Glycerol-3-phosphate responsive antiterminator Cytokin_check_N PF10407.9 ORY09312.1 - 0.029 14.3 0.7 0.061 13.3 0.7 1.4 1 0 0 1 1 1 0 Cdc14 phosphatase binding protein N-terminus AT_hook PF02178.19 ORY09312.1 - 2.1 8.5 8.5 0.42 10.6 2.0 3.2 2 0 0 2 2 2 0 AT hook motif APH PF01636.23 ORY09315.1 - 6.2e-16 59.1 0.1 8.4e-16 58.6 0.1 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 ORY09315.1 - 0.012 15.2 0.0 0.018 14.6 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Fig1 PF12351.8 ORY09316.1 - 3.3e-10 40.2 0.7 4.2e-10 39.9 0.7 1.1 1 0 0 1 1 1 1 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.12 ORY09316.1 - 0.0044 16.7 3.1 0.0057 16.3 3.1 1.1 1 0 0 1 1 1 1 SUR7/PalI family p450 PF00067.22 ORY09318.1 - 0.0049 15.7 0.0 0.0054 15.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF21 PF01595.20 ORY09320.1 - 0.023 14.4 0.6 0.035 13.8 0.6 1.4 1 1 0 1 1 1 0 Cyclin M transmembrane N-terminal domain Flavi_M PF01004.19 ORY09320.1 - 0.088 12.6 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 Flavivirus envelope glycoprotein M PMP1_2 PF08114.11 ORY09320.1 - 2 8.3 5.3 3.1 7.6 4.7 1.7 1 1 1 2 2 2 0 ATPase proteolipid family HET PF06985.11 ORY09321.1 - 8.3e-30 104.1 0.7 1.8e-29 103.0 0.7 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DCA16 PF15349.6 ORY09321.1 - 0.0038 16.8 0.7 0.012 15.2 0.4 1.9 2 1 1 3 3 3 1 DDB1- and CUL4-associated factor 16 IL17R_fnIII_D2 PF16578.5 ORY09321.1 - 0.025 15.1 0.0 0.099 13.2 0.0 2.0 2 0 0 2 2 2 0 Interleukin 17 receptor D Esterase_phd PF10503.9 ORY09322.1 - 0.00013 21.6 0.0 0.00018 21.1 0.0 1.2 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 ORY09322.1 - 0.00025 20.6 0.0 0.0004 19.9 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 ORY09322.1 - 0.0028 17.3 0.0 0.004 16.7 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Esterase PF00756.20 ORY09322.1 - 0.003 17.2 0.0 0.0035 17.0 0.0 1.3 1 0 0 1 1 1 1 Putative esterase BAAT_C PF08840.11 ORY09322.1 - 0.0098 15.8 0.0 0.016 15.2 0.0 1.2 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal DUF3433 PF11915.8 ORY09323.1 - 5.9e-35 119.6 24.0 3.8e-21 75.3 1.2 4.1 4 0 0 4 4 4 2 Protein of unknown function (DUF3433) DUF3671 PF12420.8 ORY09323.1 - 0.01 15.9 0.0 0.042 13.9 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function Ank_3 PF13606.6 ORY09324.1 - 1.7e-11 43.2 0.0 0.063 13.9 0.0 5.1 5 0 0 5 5 5 4 Ankyrin repeat Ank_2 PF12796.7 ORY09324.1 - 1.4e-10 41.6 0.0 1.1e-09 38.7 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY09324.1 - 2.4e-09 37.5 0.0 3.5e-05 24.3 0.0 3.7 1 1 3 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 ORY09324.1 - 3.2e-06 27.3 1.7 3.3 8.3 0.0 4.6 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 ORY09324.1 - 0.013 15.8 0.0 45 4.5 0.0 3.7 2 1 0 3 3 3 0 Ankyrin repeats (many copies) Raptor_N PF14538.6 ORY09325.1 - 0.00018 21.5 0.2 0.00062 19.8 0.1 1.9 2 1 0 2 2 2 1 Raptor N-terminal CASPase like domain Peptidase_C11 PF03415.14 ORY09325.1 - 0.0073 15.7 0.0 0.011 15.2 0.0 1.2 1 0 0 1 1 1 1 Clostripain family DUF1772 PF08592.11 ORY09326.1 - 0.25 11.7 2.5 0.44 10.9 2.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) ABC2_membrane_2 PF12679.7 ORY09326.1 - 0.28 10.4 4.9 0.4 9.9 4.9 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein Transferase PF02458.15 ORY09327.1 - 6.3e-06 25.1 0.0 0.00022 20.0 0.0 2.1 2 0 0 2 2 2 2 Transferase family DUF3656 PF12392.8 ORY09327.1 - 0.11 13.2 0.0 0.21 12.2 0.0 1.5 1 0 0 1 1 1 0 Collagenase Frag1 PF10277.9 ORY09328.1 - 2.7e-45 154.6 22.7 3.3e-45 154.3 22.7 1.1 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family Keratin_assoc PF09775.9 ORY09328.1 - 0.022 14.4 4.8 0.044 13.4 4.8 1.5 1 0 0 1 1 1 0 Keratinocyte-associated protein 2 HemY_N PF07219.13 ORY09328.1 - 4.6 7.5 5.9 6.3 7.0 0.0 3.4 3 2 0 3 3 3 0 HemY protein N-terminus Orn_Arg_deC_N PF02784.16 ORY09332.1 - 9.4e-83 277.4 0.0 1.3e-82 276.9 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 ORY09332.1 - 4.1e-19 68.6 0.0 5.1e-19 68.3 0.0 1.4 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Ank_5 PF13857.6 ORY09333.1 - 2.2e-06 27.8 1.7 5.9e-05 23.3 1.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 ORY09333.1 - 3.2e-06 27.6 2.3 0.0023 18.4 0.1 4.4 4 2 2 6 6 6 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 ORY09333.1 - 3.4e-06 27.5 0.3 4.7e-05 23.9 0.2 2.6 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ORY09333.1 - 0.0027 18.1 7.7 0.015 15.8 0.3 4.0 4 0 0 4 4 4 1 Ankyrin repeat Ank PF00023.30 ORY09333.1 - 0.0035 17.7 5.2 0.0074 16.7 0.4 3.1 3 0 0 3 3 3 1 Ankyrin repeat PDGF_N PF04692.13 ORY09333.1 - 2.3 9.1 6.0 1 10.2 2.2 2.1 2 0 0 2 2 2 0 Platelet-derived growth factor, N terminal region G-patch_2 PF12656.7 ORY09334.1 - 2.7e-17 62.6 0.1 2.7e-17 62.6 0.1 2.7 2 0 0 2 2 2 1 G-patch domain G-patch PF01585.23 ORY09334.1 - 0.053 13.4 0.1 0.13 12.2 0.1 1.7 1 0 0 1 1 1 0 G-patch domain MDM31_MDM32 PF08118.11 ORY09335.1 - 1.1e-213 710.7 0.0 1.2e-213 710.6 0.0 1.0 1 0 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins TraH_2 PF06871.11 ORY09335.1 - 0.12 12.0 0.1 0.23 11.1 0.1 1.4 1 0 0 1 1 1 0 TraH_2 DUF4124 PF13511.6 ORY09335.1 - 0.25 11.7 1.4 5.1 7.5 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4124) Chromate_transp PF02417.15 ORY09342.1 - 1.2e-63 213.9 38.7 1e-32 113.5 11.1 2.3 2 1 0 2 2 2 2 Chromate transporter Tcp11 PF05794.13 ORY09343.1 - 1.2e-99 334.4 0.2 1.6e-99 334.0 0.2 1.1 1 0 0 1 1 1 1 T-complex protein 11 DUF2264 PF10022.9 ORY09343.1 - 0.047 12.8 0.0 0.074 12.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2264) CTP_transf_like PF01467.26 ORY09345.1 - 1.2e-26 93.6 0.0 2.4e-26 92.6 0.0 1.5 1 0 0 1 1 1 1 Cytidylyltransferase-like AcetylCoA_hydro PF02550.15 ORY09345.1 - 0.11 12.5 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Acetyl-CoA hydrolase/transferase N-terminal domain WD40 PF00400.32 ORY09346.1 - 2.7e-33 113.5 13.4 6.7e-08 33.1 0.3 7.8 7 1 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY09346.1 - 5.2e-14 52.3 1.3 0.024 14.9 0.1 5.1 5 1 1 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.12 ORY09346.1 - 0.0034 15.5 0.2 0.056 11.4 0.2 2.3 3 0 0 3 3 3 1 IKI3 family Coatomer_WDAD PF04053.14 ORY09346.1 - 0.07 12.2 0.5 0.13 11.3 0.1 1.5 2 0 0 2 2 2 0 Coatomer WD associated region MHYT PF03707.16 ORY09347.1 - 9.6e-14 51.3 20.4 3.3e-07 30.4 0.5 4.5 4 0 0 4 4 4 4 Bacterial signalling protein N terminal repeat SWIRM-assoc_2 PF16496.5 ORY09348.1 - 0.29 10.0 1.4 0.47 9.3 1.4 1.3 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal Ribosomal_L32p PF01783.23 ORY09348.1 - 5.2 7.4 8.5 29 5.0 6.4 2.4 2 0 0 2 2 2 0 Ribosomal L32p protein family AFP_2 PF18815.1 ORY09350.1 - 0.15 12.3 2.1 0.28 11.5 0.0 2.0 1 1 1 2 2 2 0 Bacterial antifreeze protein repeat adh_short_C2 PF13561.6 ORY09351.1 - 3e-28 98.9 0.2 6.1e-26 91.4 0.2 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY09351.1 - 7.6e-23 81.0 0.2 1.2e-20 73.8 0.2 2.1 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORY09351.1 - 0.00017 21.5 0.0 0.00075 19.5 0.0 1.9 1 1 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 ORY09351.1 - 0.08 12.3 0.0 0.25 10.7 0.0 1.8 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.21 ORY09351.1 - 0.16 11.4 0.0 14 5.1 0.0 2.2 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family TruB_C PF09142.11 ORY09351.1 - 0.23 11.2 1.7 2.9 7.7 0.3 2.6 2 0 0 2 2 2 0 tRNA Pseudouridine synthase II, C terminal DHquinase_I PF01487.15 ORY09352.1 - 4.7e-45 154.6 0.0 6.8e-45 154.1 0.0 1.2 1 0 0 1 1 1 1 Type I 3-dehydroquinase Fungal_trans PF04082.18 ORY09353.1 - 8.7e-21 74.1 0.0 2.2e-20 72.8 0.0 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY09353.1 - 1.9e-05 24.7 15.9 3.1e-05 24.0 15.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pyr_redox_2 PF07992.14 ORY09354.1 - 2.3e-65 220.7 0.5 3.9e-65 220.0 0.5 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 ORY09354.1 - 5.7e-30 103.8 0.2 1.3e-29 102.7 0.2 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 ORY09354.1 - 2.7e-18 66.3 1.8 9.8e-18 64.5 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ORY09354.1 - 3.3e-13 49.6 1.7 8.5e-13 48.2 1.7 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ORY09354.1 - 7.5e-07 28.6 0.1 0.0041 16.3 0.0 2.2 1 1 1 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) FAD_oxidored PF12831.7 ORY09354.1 - 0.0002 20.8 0.4 0.002 17.5 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO PF01266.24 ORY09354.1 - 0.00043 20.0 1.2 0.024 14.2 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 ORY09354.1 - 0.0009 18.4 0.9 3.7 6.5 1.1 3.1 3 0 0 3 3 3 2 FAD binding domain AlaDh_PNT_C PF01262.21 ORY09354.1 - 0.014 14.7 1.1 0.052 12.8 0.3 2.0 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 ORY09354.1 - 0.028 13.8 0.0 3 7.2 0.0 2.5 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HI0933_like PF03486.14 ORY09354.1 - 0.034 12.9 3.0 9 4.9 0.9 3.1 3 0 0 3 3 3 0 HI0933-like protein GIDA PF01134.22 ORY09354.1 - 1.3 8.0 4.8 4.2 6.3 4.8 1.8 1 1 0 1 1 1 0 Glucose inhibited division protein A Arabinose_trans PF04602.12 ORY09355.1 - 0.012 14.4 0.0 0.015 14.2 0.0 1.0 1 0 0 1 1 1 0 Mycobacterial cell wall arabinan synthesis protein Mito_carr PF00153.27 ORY09356.1 - 1.1e-43 147.1 5.0 3.9e-16 58.7 0.1 4.3 3 1 0 3 3 3 3 Mitochondrial carrier protein Peptidase_M26_C PF07580.14 ORY09357.1 - 0.0016 17.1 0.6 0.0026 16.4 0.6 1.2 1 0 0 1 1 1 1 M26 IgA1-specific Metallo-endopeptidase C-terminal region Phage_holin_3_6 PF07332.11 ORY09357.1 - 0.024 14.7 0.3 0.058 13.4 0.1 1.8 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Fzo_mitofusin PF04799.13 ORY09357.1 - 0.091 12.3 1.8 16 5.0 0.0 3.3 4 0 0 4 4 4 0 fzo-like conserved region ETRAMP PF09716.10 ORY09357.1 - 0.76 9.9 2.7 4.2 7.5 0.0 2.6 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Adaptin_binding PF10199.9 ORY09357.1 - 1.3 9.6 4.4 56 4.4 0.0 3.2 3 1 0 3 3 3 0 Alpha and gamma adaptin binding protein p34 Helo_like_N PF17111.5 ORY09361.1 - 3.4e-07 29.8 0.1 3.4e-07 29.8 0.1 2.3 2 1 0 2 2 2 1 Fungal N-terminal domain of STAND proteins LPP PF04728.13 ORY09361.1 - 0.068 13.6 0.9 6.2 7.3 0.0 2.9 3 0 0 3 3 3 0 Lipoprotein leucine-zipper HEPN PF05168.14 ORY09361.1 - 0.11 12.6 0.3 0.57 10.3 0.0 2.1 2 0 0 2 2 2 0 HEPN domain FliT PF05400.13 ORY09361.1 - 0.11 13.3 6.3 0.37 11.6 0.3 2.4 2 0 0 2 2 2 0 Flagellar protein FliT DUF4665 PF15679.5 ORY09361.1 - 0.14 12.8 1.7 5.5 7.7 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4665) Golgin_A5 PF09787.9 ORY09361.1 - 0.47 9.9 8.8 0.39 10.1 0.1 2.3 2 1 0 2 2 2 0 Golgin subfamily A member 5 HeLo PF14479.6 ORY09362.1 - 0.02 14.7 0.6 0.034 14.0 0.6 1.3 1 0 0 1 1 1 0 Prion-inhibition and propagation Pkinase_Tyr PF07714.17 ORY09362.1 - 0.065 12.5 0.1 0.44 9.8 0.1 2.0 1 1 0 1 1 1 0 Protein tyrosine kinase D5_N PF08706.11 ORY09362.1 - 0.15 12.4 0.3 0.44 10.8 0.3 1.8 1 0 0 1 1 1 0 D5 N terminal like Pkinase PF00069.25 ORY09363.1 - 6.2e-36 124.1 0.1 7.8e-36 123.8 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY09363.1 - 1.2e-25 90.3 0.1 1.6e-25 89.9 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 ORY09363.1 - 0.029 13.3 0.8 1.5 7.7 0.2 2.1 1 1 1 2 2 2 0 Poxvirus serine/threonine protein kinase Kdo PF06293.14 ORY09363.1 - 0.051 12.9 0.9 0.087 12.2 0.5 1.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF956 PF06115.11 ORY09363.1 - 0.16 11.7 0.1 5.3 6.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF956) GMC_oxred_N PF00732.19 ORY09364.1 - 6.8e-62 209.5 0.0 8.9e-62 209.1 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 ORY09364.1 - 4e-38 131.2 0.1 7.1e-38 130.4 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Thi4 PF01946.17 ORY09364.1 - 3.7e-06 26.3 0.4 2.8e-05 23.5 0.1 2.1 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 ORY09364.1 - 1.1e-05 25.2 0.6 0.00012 21.8 0.6 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ORY09364.1 - 2.3e-05 24.5 0.0 6.4e-05 23.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 ORY09364.1 - 4.8e-05 22.6 0.1 0.00031 19.9 0.0 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 ORY09364.1 - 0.00051 19.4 0.1 0.29 10.3 0.0 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ORY09364.1 - 0.00072 18.7 0.0 0.014 14.5 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 ORY09364.1 - 0.0041 16.4 0.2 0.074 12.3 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ORY09364.1 - 0.0057 15.4 0.1 0.033 12.9 0.0 1.9 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_9 PF13454.6 ORY09364.1 - 0.078 13.0 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding SUR7 PF06687.12 ORY09367.1 - 6.4e-39 133.8 19.4 7.8e-39 133.5 19.4 1.1 1 0 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.8 ORY09367.1 - 4.2 7.2 18.6 0.37 10.7 13.2 1.8 1 1 1 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 DUF4400 PF14348.6 ORY09367.1 - 7.1 6.1 10.6 1.1 8.7 6.6 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4400) Lyase_1 PF00206.20 ORY09368.1 - 1.2e-21 77.5 0.0 1.9e-21 76.8 0.0 1.2 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 ORY09368.1 - 2e-18 66.7 0.0 7.4e-18 64.9 0.0 2.0 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus RNA_pol_Rbc25 PF08292.12 ORY09368.1 - 0.055 13.7 0.4 0.12 12.6 0.4 1.5 1 0 0 1 1 1 0 RNA polymerase III subunit Rpc25 zf-RING_2 PF13639.6 ORY09369.1 - 8.8e-08 32.4 5.5 8.8e-08 32.4 5.5 2.3 2 0 0 2 2 2 1 Ring finger domain FANCL_C PF11793.8 ORY09369.1 - 2.9e-05 24.1 6.2 7.8e-05 22.8 6.2 1.7 1 0 0 1 1 1 1 FANCL C-terminal domain zf-ANAPC11 PF12861.7 ORY09369.1 - 0.0054 16.8 7.3 0.0096 16.0 1.7 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.7 ORY09369.1 - 0.014 15.5 5.1 0.014 15.5 5.1 2.3 3 0 0 3 3 3 0 RING-variant domain zf-rbx1 PF12678.7 ORY09369.1 - 0.02 15.2 6.1 0.02 15.2 6.1 2.8 2 1 0 2 2 2 0 RING-H2 zinc finger domain AT_hook PF02178.19 ORY09369.1 - 0.031 14.1 12.2 1.2 9.3 3.4 3.1 2 0 0 2 2 2 0 AT hook motif SnAC PF14619.6 ORY09369.1 - 0.076 13.6 2.7 3.6 8.3 0.2 2.7 2 0 0 2 2 2 0 Snf2-ATP coupling, chromatin remodelling complex zf-RING_UBOX PF13445.6 ORY09369.1 - 0.1 12.7 3.3 0.25 11.4 3.3 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4 PF00097.25 ORY09369.1 - 0.17 11.8 12.3 0.051 13.5 3.3 2.6 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 ORY09369.1 - 0.68 9.9 7.2 1.5 8.8 7.2 1.6 1 0 0 1 1 1 0 PHD-finger zf-C3HC4_2 PF13923.6 ORY09369.1 - 4.5 7.2 16.7 0.18 11.6 5.4 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 ORY09369.1 - 4.8 7.0 8.3 12 5.8 8.3 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 ORY09369.1 - 8.2 6.4 12.4 0.31 10.9 3.3 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) UCR_14kD PF02271.16 ORY09370.1 - 6.1e-46 154.5 0.1 7.4e-46 154.2 0.1 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Mito_carr PF00153.27 ORY09371.1 - 3.6e-28 97.3 0.1 8.1e-17 60.9 0.0 2.3 2 1 0 2 2 2 2 Mitochondrial carrier protein HhH-GPD PF00730.25 ORY09372.1 - 3.6e-11 43.5 0.0 1.2e-10 41.8 0.0 1.8 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein HMG14_17 PF01101.18 ORY09372.1 - 0.021 15.8 5.3 0.021 15.8 5.3 2.4 2 0 0 2 2 2 0 HMG14 and HMG17 FYRN PF05964.14 ORY09374.1 - 0.029 14.2 0.3 0.09 12.6 0.3 1.8 1 0 0 1 1 1 0 F/Y-rich N-terminus Ecm33 PF12454.8 ORY09375.1 - 3.5e-10 39.9 1.4 3.5e-10 39.9 1.4 2.4 3 0 0 3 3 3 1 GPI-anchored cell wall organization protein Recep_L_domain PF01030.24 ORY09375.1 - 1.7e-07 31.4 9.2 0.028 14.5 0.0 4.3 2 2 1 3 3 3 2 Receptor L domain LRR_5 PF13306.6 ORY09375.1 - 0.00012 22.1 4.9 0.0049 16.8 0.2 2.5 2 0 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 ORY09375.1 - 0.11 13.0 18.5 0.94 10.0 2.5 5.8 1 1 3 5 5 5 0 Leucine Rich repeats (2 copies) S_4TM PF18159.1 ORY09376.1 - 0.0079 15.5 0.2 0.012 14.9 0.2 1.2 1 0 0 1 1 1 1 SMODS-associating 4TM effector domain WhiA_N PF10298.9 ORY09376.1 - 0.046 13.8 0.0 0.097 12.7 0.0 1.5 1 0 0 1 1 1 0 WhiA N-terminal LAGLIDADG-like domain EURL PF06937.11 ORY09376.1 - 0.063 12.7 1.1 0.088 12.2 1.1 1.2 1 0 0 1 1 1 0 EURL protein Nckap1 PF09735.9 ORY09376.1 - 0.084 10.8 0.9 0.1 10.6 0.9 1.1 1 0 0 1 1 1 0 Membrane-associated apoptosis protein YqfQ PF14181.6 ORY09376.1 - 0.14 12.3 4.4 0.26 11.5 4.4 1.5 1 0 0 1 1 1 0 YqfQ-like protein Anp1 PF03452.14 ORY09377.1 - 7.3e-108 360.0 0.0 9.1e-108 359.6 0.0 1.1 1 0 0 1 1 1 1 Anp1 HATPase_c_3 PF13589.6 ORY09378.1 - 1.4e-17 63.8 0.0 3.6e-17 62.5 0.0 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.11 ORY09378.1 - 9.9e-07 28.6 0.0 1.5e-05 24.8 0.0 2.8 2 1 0 2 2 2 1 MutL C terminal dimerisation domain HATPase_c PF02518.26 ORY09378.1 - 0.00029 21.3 0.0 0.00066 20.2 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase G-patch PF01585.23 ORY09381.1 - 1.7e-13 50.2 0.7 3.4e-13 49.2 0.7 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 ORY09381.1 - 0.06 13.4 0.4 0.13 12.4 0.4 1.6 1 0 0 1 1 1 0 G-patch domain AMP-binding PF00501.28 ORY09382.1 - 7.4e-91 304.8 0.0 8.7e-91 304.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORY09382.1 - 1.2e-13 51.8 0.2 4.1e-13 50.1 0.2 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GH3 PF03321.13 ORY09382.1 - 4.2e-05 22.6 0.0 0.00054 18.9 0.0 2.2 2 0 0 2 2 2 1 GH3 auxin-responsive promoter RTX_C PF08339.10 ORY09382.1 - 0.0097 16.0 0.0 0.027 14.5 0.0 1.7 1 1 0 1 1 1 1 RTX C-terminal domain APH PF01636.23 ORY09386.1 - 7.7e-13 48.9 0.1 2e-11 44.3 0.1 2.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 ORY09386.1 - 0.00034 20.3 0.0 0.00055 19.6 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Sorb PF02208.16 ORY09386.1 - 1.8 8.4 5.9 0.5 10.3 0.2 2.5 2 0 0 2 2 2 0 Sorbin homologous domain Polysacc_deac_1 PF01522.21 ORY09388.1 - 4e-23 81.6 0.0 6.1e-23 81.1 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase HTH_39 PF14090.6 ORY09388.1 - 0.01 15.6 0.1 0.021 14.5 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Polysacc_deac_2 PF04748.13 ORY09388.1 - 0.13 11.5 0.0 0.29 10.3 0.0 1.6 2 0 0 2 2 2 0 Divergent polysaccharide deacetylase AAA_12 PF13087.6 ORY09389.1 - 1.8e-07 31.0 0.0 2.3e-07 30.7 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 ORY09389.1 - 2.3e-07 30.9 0.0 3.3e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 ORY09389.1 - 0.0019 17.9 0.0 0.0022 17.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain DUF2968 PF11180.8 ORY09389.1 - 0.1 12.2 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) Peptidase_S8 PF00082.22 ORY09390.1 - 9.5e-09 34.9 0.1 1.9e-08 34.0 0.1 1.5 1 0 0 1 1 1 1 Subtilase family S6PP PF05116.13 ORY09390.1 - 0.058 12.9 0.0 0.093 12.2 0.0 1.2 1 0 0 1 1 1 0 Sucrose-6F-phosphate phosphohydrolase KRBA1 PF15287.6 ORY09390.1 - 3.4 7.4 0.0 3.4 7.4 0.0 3.2 4 0 0 4 4 4 0 KRBA1 family repeat Mur_ligase_M PF08245.12 ORY09392.1 - 0.00023 21.2 0.0 0.00036 20.6 0.0 1.3 1 0 0 1 1 1 1 Mur ligase middle domain DUF4140 PF13600.6 ORY09392.1 - 0.13 12.7 0.2 0.39 11.2 0.2 1.8 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Sugar_tr PF00083.24 ORY09393.1 - 2.9e-140 468.1 24.5 3.4e-140 467.9 24.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY09393.1 - 6.5e-23 81.2 49.1 2.6e-17 62.8 28.7 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Pox_A14 PF05767.12 ORY09393.1 - 0.35 11.1 2.3 0.87 9.8 0.0 2.9 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 Ydc2-catalyt PF09159.10 ORY09394.1 - 3.4e-68 230.4 0.0 4.2e-68 230.1 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 Pox_A22 PF04848.13 ORY09394.1 - 3.9e-05 23.8 0.0 1.4 9.0 0.0 3.5 3 0 0 3 3 3 3 Poxvirus A22 protein SAP PF02037.27 ORY09394.1 - 0.0084 15.8 0.2 0.019 14.7 0.2 1.6 1 0 0 1 1 1 1 SAP domain Mid2 PF04478.12 ORY09396.1 - 0.0011 18.8 1.5 0.0011 18.8 0.6 1.5 1 1 0 1 1 1 1 Mid2 like cell wall stress sensor PRCC PF10253.9 ORY09396.1 - 0.014 16.2 2.7 0.016 16.0 2.7 1.3 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Orthopox_C10L PF07020.11 ORY09396.1 - 0.16 12.8 7.7 0.33 11.7 7.7 1.6 1 0 0 1 1 1 0 Orthopoxvirus C10L protein Ndc1_Nup PF09531.10 ORY09396.1 - 0.62 8.7 3.8 0.71 8.5 3.8 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PQ-loop PF04193.14 ORY09397.1 - 2.8e-38 129.5 6.9 2.2e-19 69.0 0.1 3.1 2 1 1 3 3 3 2 PQ loop repeat FeoB_associated PF12669.7 ORY09397.1 - 5.8 7.4 5.6 51 4.4 0.5 3.5 4 0 0 4 4 4 0 FeoB-associated Cys-rich membrane protein Asn_synthase PF00733.21 ORY09398.1 - 8.9e-90 301.9 0.0 2.4e-52 178.8 0.0 2.1 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 ORY09398.1 - 2e-35 121.4 0.0 3.1e-35 120.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 ORY09398.1 - 1.7e-26 93.0 0.0 3e-26 92.2 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 ORY09398.1 - 2.1e-06 27.4 0.0 3.8e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.17 ORY09398.1 - 0.015 14.4 0.0 0.027 13.6 0.0 1.3 1 0 0 1 1 1 0 NAD synthase Motile_Sperm PF00635.26 ORY09399.1 - 3.9e-27 94.2 0.2 1.2e-26 92.6 0.1 1.9 1 1 1 2 2 2 1 MSP (Major sperm protein) domain Apolipoprotein PF01442.18 ORY09399.1 - 0.001 19.0 2.5 0.0016 18.3 2.5 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain ATG16 PF08614.11 ORY09399.1 - 0.0064 16.7 3.4 0.0097 16.1 3.4 1.3 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) ASH PF15780.5 ORY09399.1 - 0.0082 16.3 0.0 0.029 14.6 0.0 1.9 2 0 0 2 2 2 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin DUF883 PF05957.13 ORY09399.1 - 0.01 16.4 1.3 0.021 15.4 1.0 1.7 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Flg_hook PF02120.16 ORY09399.1 - 0.06 13.2 3.0 1.2 9.1 0.5 3.2 2 1 1 3 3 3 0 Flagellar hook-length control protein FliK SlyX PF04102.12 ORY09399.1 - 0.081 13.6 1.3 0.2 12.3 1.3 1.6 1 0 0 1 1 1 0 SlyX Hydantoinase_B PF02538.14 ORY09399.1 - 0.085 11.3 0.2 0.12 10.8 0.2 1.1 1 0 0 1 1 1 0 Hydantoinase B/oxoprolinase DotU PF09850.9 ORY09399.1 - 0.1 12.3 0.1 0.18 11.5 0.1 1.4 1 0 0 1 1 1 0 Type VI secretion system protein DotU CCDC158 PF15921.5 ORY09399.1 - 0.11 10.4 0.4 0.16 9.8 0.4 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 158 CAML PF14963.6 ORY09399.1 - 0.28 11.3 1.1 0.49 10.5 1.1 1.3 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand DUF4407 PF14362.6 ORY09399.1 - 0.47 9.8 4.7 0.71 9.2 4.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) KfrA_N PF11740.8 ORY09399.1 - 0.65 10.7 7.3 0.56 10.9 4.7 2.1 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term UBX PF00789.20 ORY09400.1 - 7.8e-08 32.4 0.0 1.7e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 UBX domain UBA PF00627.31 ORY09400.1 - 0.00022 21.0 0.0 0.00073 19.4 0.0 1.9 2 0 0 2 2 2 1 UBA/TS-N domain zf-C2H2_2 PF12756.7 ORY09400.1 - 0.011 16.0 0.2 0.028 14.8 0.2 1.7 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Tir_receptor_N PF07490.11 ORY09400.1 - 0.23 11.3 1.7 0.41 10.4 1.7 1.4 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) N-terminus Glyco_transf_4 PF13439.6 ORY09400.1 - 0.23 11.5 0.0 0.42 10.6 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase Family 4 zf-C2H2_aberr PF17017.5 ORY09400.1 - 0.53 10.4 2.7 0.98 9.5 2.7 1.5 1 0 0 1 1 1 0 Aberrant zinc-finger zf-C2H2_3rep PF18868.1 ORY09400.1 - 3.2 8.4 9.6 0.16 12.6 0.7 2.4 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats DEAD PF00270.29 ORY09401.1 - 2.9e-17 63.0 0.0 5.4e-17 62.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY09401.1 - 5.8e-15 55.6 0.0 1.2e-12 48.1 0.0 2.7 3 0 0 3 3 3 2 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 ORY09401.1 - 2.5e-12 47.3 1.4 5.2e-12 46.3 1.4 1.6 1 0 0 1 1 1 1 RecQ zinc-binding Acetyltransf_1 PF00583.25 ORY09402.1 - 1.4e-08 35.0 0.0 1.7e-08 34.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ORY09402.1 - 4.3e-07 29.9 0.0 5.2e-07 29.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ORY09402.1 - 1.7e-06 28.4 0.0 2.1e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ORY09402.1 - 9.2e-06 25.6 0.0 1.4e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein He_PIG PF05345.12 ORY09403.1 - 1.7e-22 79.3 15.1 4.1e-07 30.1 0.3 4.9 4 0 0 4 4 4 4 Putative Ig domain Plasmodium_Vir PF05795.11 ORY09403.1 - 0.0066 15.9 1.2 0.016 14.7 0.0 2.1 2 0 0 2 2 2 1 Plasmodium vivax Vir protein Amnionless PF14828.6 ORY09403.1 - 0.063 12.1 0.0 0.14 11.0 0.0 1.5 1 0 0 1 1 1 0 Amnionless Sarcoglycan_2 PF05510.13 ORY09403.1 - 0.085 11.6 0.0 10 4.7 0.0 2.2 2 0 0 2 2 2 0 Sarcoglycan alpha/epsilon SET PF00856.28 ORY09409.1 - 6.8e-11 42.9 0.0 2.3e-10 41.1 0.0 2.1 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.18 ORY09409.1 - 5.9e-09 35.9 11.4 5.9e-09 35.9 11.4 2.4 2 0 0 2 2 2 1 MYND finger HET PF06985.11 ORY09411.1 - 2.4e-11 44.2 10.0 1e-09 38.9 1.2 2.8 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) GerA PF03323.13 ORY09412.1 - 1.8 7.0 4.3 2.6 6.4 4.3 1.2 1 0 0 1 1 1 0 Bacillus/Clostridium GerA spore germination protein Na_H_Exchanger PF00999.21 ORY09414.1 - 8.9e-16 57.6 35.7 2.5e-08 33.2 21.2 2.2 2 1 0 2 2 2 2 Sodium/hydrogen exchanger family FAD_binding_3 PF01494.19 ORY09415.1 - 1e-48 166.4 0.0 1.2e-48 166.1 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 ORY09415.1 - 5e-07 29.2 0.4 0.015 14.4 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.6 ORY09415.1 - 2e-05 24.0 0.6 0.0056 16.0 0.1 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ORY09415.1 - 4.3e-05 22.9 0.0 8.6e-05 21.9 0.0 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ORY09415.1 - 0.00035 19.4 0.3 0.073 11.8 0.1 2.1 2 0 0 2 2 2 2 HI0933-like protein DAO PF01266.24 ORY09415.1 - 0.00068 19.3 1.9 0.018 14.6 0.1 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 ORY09415.1 - 0.01 14.9 0.0 0.016 14.3 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_oxidored PF12831.7 ORY09415.1 - 0.013 14.9 0.7 0.096 12.0 1.0 2.1 2 1 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ORY09415.1 - 0.019 15.2 0.0 0.047 13.9 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain SnoaL_2 PF12680.7 ORY09415.1 - 0.14 12.8 0.1 0.28 11.8 0.1 1.5 1 0 0 1 1 1 0 SnoaL-like domain p450 PF00067.22 ORY09416.1 - 5.2e-60 203.5 0.0 8.8e-60 202.7 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 Hce2 PF14856.6 ORY09417.1 - 2.2e-16 60.0 0.8 2.6e-16 59.8 0.8 1.1 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor CRF PF00473.17 ORY09418.1 - 0.11 12.5 0.1 0.31 11.1 0.1 1.7 1 0 0 1 1 1 0 Corticotropin-releasing factor family FSH1 PF03959.13 ORY09419.1 - 1e-27 97.2 0.0 1.4e-27 96.8 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.13 ORY09419.1 - 0.11 12.3 0.6 0.3 10.9 0.2 2.0 2 1 0 2 2 2 0 alpha/beta hydrolase fold F-box PF00646.33 ORY09422.1 - 1.6e-06 27.8 0.2 3.3e-06 26.8 0.2 1.5 1 0 0 1 1 1 1 F-box domain SH3_9 PF14604.6 ORY09423.1 - 1.5e-30 104.8 4.8 6e-15 54.8 0.3 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 ORY09423.1 - 6.1e-28 96.2 4.9 3.7e-13 48.9 0.1 2.5 2 0 0 2 2 2 2 SH3 domain Cofilin_ADF PF00241.20 ORY09423.1 - 2.3e-15 56.5 0.0 4.4e-15 55.5 0.0 1.4 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein SH3_2 PF07653.17 ORY09423.1 - 4e-15 55.2 0.0 1.6e-07 30.9 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain MMS19_C PF12460.8 ORY09424.1 - 8.5e-108 361.2 10.5 2.9e-107 359.4 4.8 3.5 3 0 0 3 3 3 1 RNAPII transcription regulator C-terminal MMS19_N PF14500.6 ORY09424.1 - 5.3e-95 317.9 4.0 1.5e-91 306.6 0.0 4.3 5 0 0 5 5 5 2 Dos2-interacting transcription regulator of RNA-Pol-II Cnd1 PF12717.7 ORY09424.1 - 0.0014 18.7 3.2 4.5 7.3 0.2 4.2 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 ORY09424.1 - 0.0027 18.1 9.6 0.77 10.2 0.2 5.2 6 1 0 6 6 6 2 HEAT repeats RTP1_C1 PF10363.9 ORY09424.1 - 0.0071 16.5 2.5 0.2 11.9 0.0 3.9 4 0 0 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 ORY09424.1 - 0.029 14.9 19.2 0.13 12.8 0.4 7.2 9 1 1 10 10 10 0 HEAT-like repeat RIX1 PF08167.12 ORY09424.1 - 0.1 12.3 0.1 0.1 12.3 0.1 4.2 4 1 0 5 5 5 0 rRNA processing/ribosome biogenesis Telomere_reg-2 PF10193.9 ORY09424.1 - 0.14 12.6 1.6 42 4.6 0.1 4.0 4 0 0 4 4 4 0 Telomere length regulation protein HEAT PF02985.22 ORY09424.1 - 1.5 9.3 10.1 69 4.1 0.1 6.4 6 0 0 6 6 6 0 HEAT repeat THF_DHG_CYH PF00763.23 ORY09425.1 - 9.7e-25 87.1 0.0 1.4e-24 86.5 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.19 ORY09425.1 - 2.2e-13 49.8 0.0 7.5e-10 38.4 0.0 2.7 2 1 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Brix PF04427.18 ORY09426.1 - 1.3e-38 133.1 0.6 1.8e-38 132.6 0.6 1.2 1 0 0 1 1 1 1 Brix domain RNA_pol_Rpo13 PF12136.8 ORY09426.1 - 2.6 8.0 7.8 19 5.3 0.0 2.5 2 0 0 2 2 2 0 RNA polymerase Rpo13 subunit HTH domain MBOAT_2 PF13813.6 ORY09427.1 - 4.9e-13 49.2 0.2 1.6e-12 47.5 0.1 2.0 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family PIR PF00399.19 ORY09428.1 - 2.9e-06 26.7 6.4 1.1e-05 24.8 6.4 2.1 1 0 0 1 1 1 1 Yeast PIR protein repeat Sugar_tr PF00083.24 ORY09429.1 - 3e-24 85.7 22.5 2.1e-14 53.2 8.5 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter Baculo_p74 PF04583.12 ORY09429.1 - 0.23 10.9 2.1 0.39 10.2 2.1 1.3 1 0 0 1 1 1 0 Baculoviridae p74 conserved region DUF347 PF03988.12 ORY09429.1 - 0.35 11.1 6.7 0.69 10.2 1.1 3.5 3 0 0 3 3 3 0 Repeat of Unknown Function (DUF347) GKAP PF03359.13 ORY09430.1 - 0.037 13.6 1.3 0.04 13.5 1.3 1.0 1 0 0 1 1 1 0 Guanylate-kinase-associated protein (GKAP) protein Orf78 PF06024.12 ORY09431.1 - 0.15 12.4 0.0 0.32 11.3 0.0 1.5 1 0 0 1 1 1 0 Orf78 (ac78) SNARE PF05739.19 ORY09431.1 - 0.87 9.6 5.8 3.2 7.8 5.8 2.0 1 0 0 1 1 1 0 SNARE domain Glyco_transf_34 PF05637.12 ORY09433.1 - 5.9e-68 229.1 1.2 7.8e-68 228.8 1.2 1.1 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Herpes_pp38 PF04846.13 ORY09435.1 - 0.1 12.5 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus pp38 phosphoprotein TAFII55_N PF04658.13 ORY09436.1 - 3.7e-48 163.3 0.1 1.2e-47 161.6 0.0 1.9 2 0 0 2 2 2 1 TAFII55 protein conserved region IFP_35_N PF07334.13 ORY09436.1 - 9 6.5 7.7 48 4.1 7.1 2.4 1 1 1 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Bromo_TP PF07524.13 ORY09437.1 - 7.8e-10 38.6 0.0 2.1e-09 37.3 0.0 1.7 2 0 0 2 2 2 1 Bromodomain associated TFIID-31kDa PF02291.15 ORY09437.1 - 0.0014 18.7 0.0 0.0025 17.9 0.0 1.5 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Cupin_8 PF13621.6 ORY09438.1 - 5.7e-11 42.6 0.0 1.2e-08 35.0 0.0 2.2 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 ORY09438.1 - 5.8e-08 33.2 0.2 0.0053 17.2 0.0 2.3 2 0 0 2 2 2 2 JmjC domain, hydroxylase F-box-like PF12937.7 ORY09438.1 - 1.5e-05 24.8 0.0 6.6e-05 22.7 0.0 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 ORY09438.1 - 0.00057 19.7 0.0 0.0012 18.7 0.0 1.5 1 0 0 1 1 1 1 F-box domain DEAD PF00270.29 ORY09439.1 - 7.4e-46 156.1 1.3 1.2e-45 155.5 1.3 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY09439.1 - 8.9e-32 109.7 0.3 9.3e-31 106.5 0.1 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY09439.1 - 7.5e-07 29.3 0.0 1.1e-06 28.7 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 ORY09439.1 - 0.00048 19.9 0.1 0.00096 18.9 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 ORY09439.1 - 0.0011 19.3 0.9 0.0077 16.6 0.4 2.2 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 ORY09439.1 - 0.0061 16.8 0.3 0.022 15.0 0.3 1.9 1 1 0 1 1 1 1 AAA domain CMS1 PF14617.6 ORY09439.1 - 0.0078 15.6 0.2 0.018 14.4 0.0 1.7 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit IL17R_D_N PF16742.5 ORY09439.1 - 0.06 13.4 0.0 0.16 12.0 0.0 1.7 1 0 0 1 1 1 0 N-terminus of interleukin 17 receptor D fragilysinNterm PF16376.5 ORY09439.1 - 0.11 12.3 0.0 0.32 10.7 0.0 1.7 1 0 0 1 1 1 0 N-terminal domain of fragilysin UvrD-helicase PF00580.21 ORY09439.1 - 0.11 11.9 0.1 0.2 11.2 0.0 1.4 1 1 0 1 1 1 0 UvrD/REP helicase N-terminal domain PX PF00787.24 ORY09440.1 - 6.3e-19 68.0 0.5 2.3e-18 66.2 0.5 2.0 1 0 0 1 1 1 1 PX domain Vps5 PF09325.10 ORY09440.1 - 9.5e-10 38.4 6.6 1.3e-05 24.9 0.4 2.1 2 0 0 2 2 2 2 Vps5 C terminal like BAR PF03114.18 ORY09440.1 - 0.019 14.6 5.6 0.25 11.0 5.6 2.1 1 1 0 1 1 1 0 BAR domain Sec34 PF04136.15 ORY09440.1 - 0.043 13.7 0.5 0.043 13.7 0.5 2.1 2 0 0 2 2 2 0 Sec34-like family APG6_N PF17675.1 ORY09440.1 - 0.63 10.6 14.4 1.6 9.2 5.4 3.4 3 1 1 4 4 4 0 Apg6 coiled-coil region DUF4404 PF14357.6 ORY09440.1 - 0.95 10.1 3.4 0.65 10.7 0.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) BRE1 PF08647.11 ORY09440.1 - 4.7 7.3 7.3 12 6.0 0.2 3.5 4 0 0 4 4 4 0 BRE1 E3 ubiquitin ligase ADIP PF11559.8 ORY09440.1 - 8.2 6.5 8.8 2.2 8.4 0.4 3.0 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding ADK PF00406.22 ORY09441.1 - 6.8e-37 126.9 0.0 2.9e-19 69.6 0.0 2.1 2 0 0 2 2 2 2 Adenylate kinase AAA_17 PF13207.6 ORY09441.1 - 3.3e-15 56.7 0.0 1.5e-10 41.6 0.0 2.3 1 1 0 2 2 2 2 AAA domain ADK_lid PF05191.14 ORY09441.1 - 1.2e-14 53.9 0.0 2.1e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.6 ORY09441.1 - 5.7e-05 23.7 0.0 0.00022 21.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 ORY09441.1 - 0.015 15.4 0.0 0.03 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 ORY09441.1 - 0.075 12.0 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 ORY09441.1 - 0.16 12.3 0.0 0.25 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 ORY09441.1 - 0.17 11.9 0.0 0.38 10.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) LETM1 PF07766.13 ORY09442.1 - 3.1e-107 357.9 1.2 3.1e-107 357.9 1.2 1.7 2 0 0 2 2 2 1 LETM1-like protein SAP PF02037.27 ORY09442.1 - 0.00016 21.3 0.0 0.0011 18.7 0.0 2.4 2 0 0 2 2 2 1 SAP domain BPL_N PF09825.9 ORY09442.1 - 0.29 10.2 7.5 0.06 12.4 0.4 2.3 2 1 0 2 2 2 0 Biotin-protein ligase, N terminal Nop14 PF04147.12 ORY09443.1 - 2.5e-242 806.9 22.0 1.4e-189 632.4 11.3 2.3 1 1 1 2 2 2 2 Nop14-like family Sec23_helical PF04815.15 ORY09443.1 - 0.13 12.1 0.0 2.3 8.1 0.0 2.5 2 0 0 2 2 2 0 Sec23/Sec24 helical domain HEAT_2 PF13646.6 ORY09444.1 - 0.0044 17.4 0.1 0.01 16.2 0.1 1.6 1 0 0 1 1 1 1 HEAT repeats PaaA_PaaC PF05138.12 ORY09444.1 - 0.024 13.8 0.2 0.045 12.9 0.0 1.5 2 0 0 2 2 2 0 Phenylacetic acid catabolic protein DUF2417 PF10329.9 ORY09445.1 - 7.7e-88 293.9 1.5 1.1e-87 293.4 1.5 1.2 1 0 0 1 1 1 1 Region of unknown function (DUF2417) Abhydrolase_6 PF12697.7 ORY09446.1 - 2.5e-21 77.3 0.8 3.8e-21 76.7 0.8 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORY09446.1 - 1.3e-05 24.6 0.2 2.1e-05 23.9 0.2 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ORY09446.1 - 3e-05 23.8 0.5 0.00015 21.5 0.1 2.2 2 1 0 2 2 2 1 alpha/beta hydrolase fold Thioesterase PF00975.20 ORY09446.1 - 0.0033 17.6 0.4 0.017 15.3 0.1 2.2 1 1 0 2 2 2 1 Thioesterase domain Lipase_3 PF01764.25 ORY09446.1 - 0.061 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Cutinase PF01083.22 ORY09446.1 - 0.062 13.2 0.1 0.11 12.5 0.1 1.3 1 0 0 1 1 1 0 Cutinase PGAP1 PF07819.13 ORY09446.1 - 0.071 12.8 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_5 PF12695.7 ORY09446.1 - 0.16 11.8 0.0 0.44 10.3 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase family Fcf1 PF04900.12 ORY09447.1 - 1.2e-31 109.1 0.2 1.9e-31 108.4 0.2 1.3 1 0 0 1 1 1 1 Fcf1 DUF726 PF05277.12 ORY09448.1 - 7.5e-124 413.1 3.8 1.1e-123 412.5 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Pkinase PF00069.25 ORY09449.1 - 6.1e-37 127.4 0.0 5.8e-20 71.8 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORY09449.1 - 1.5e-15 57.2 0.0 8.3e-15 54.8 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 ORY09449.1 - 0.00058 19.8 0.0 0.00091 19.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 ORY09449.1 - 0.054 12.8 0.0 6.3 6.0 0.0 2.2 2 0 0 2 2 2 0 Kinase-like Peptidase_S9 PF00326.21 ORY09450.1 - 3.9e-49 167.0 0.1 6.8e-49 166.2 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family PD40 PF07676.12 ORY09450.1 - 1.3e-05 25.0 0.3 0.00011 22.0 0.0 2.5 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat AXE1 PF05448.12 ORY09450.1 - 0.081 11.6 0.3 3.5 6.2 0.2 2.3 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) Ank_4 PF13637.6 ORY09451.1 - 2.3e-14 53.5 0.0 7.3e-08 32.8 0.0 3.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 ORY09451.1 - 3.3e-10 40.4 0.0 2.7e-09 37.5 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) HET PF06985.11 ORY09451.1 - 1.7e-09 38.1 12.0 6.7e-08 33.0 5.5 2.6 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) AAA_16 PF13191.6 ORY09451.1 - 1e-06 29.2 3.3 1.4e-05 25.5 0.2 3.3 3 1 0 3 3 3 1 AAA ATPase domain Ank PF00023.30 ORY09451.1 - 2.2e-06 27.8 0.0 0.00038 20.8 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeat NACHT PF05729.12 ORY09451.1 - 2.6e-06 27.5 0.1 1.1e-05 25.4 0.1 2.1 1 0 0 1 1 1 1 NACHT domain KAP_NTPase PF07693.14 ORY09451.1 - 3.9e-06 26.3 0.2 0.0039 16.5 0.0 3.3 3 1 0 4 4 4 1 KAP family P-loop domain Ank_3 PF13606.6 ORY09451.1 - 6.8e-05 23.0 0.0 0.0067 16.9 0.0 3.5 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 ORY09451.1 - 0.00013 22.2 0.1 0.00029 21.1 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) AAA_22 PF13401.6 ORY09451.1 - 0.00036 20.8 0.0 0.003 17.8 0.0 2.6 2 1 1 3 3 3 1 AAA domain ABC_tran PF00005.27 ORY09451.1 - 0.054 14.0 0.0 0.26 11.8 0.0 2.2 2 1 0 2 2 2 0 ABC transporter RNA_helicase PF00910.22 ORY09451.1 - 0.13 12.6 0.0 2.1 8.8 0.0 2.7 2 0 0 2 2 2 0 RNA helicase Ank_4 PF13637.6 ORY09452.1 - 4e-12 46.4 0.0 3.3e-05 24.3 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 ORY09452.1 - 3e-11 43.2 0.9 0.00021 21.6 0.1 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 ORY09452.1 - 1.1e-09 38.8 0.1 3.3e-09 37.2 0.1 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ORY09452.1 - 5.7e-08 32.4 0.0 0.0072 16.8 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 ORY09452.1 - 0.00042 20.6 0.2 0.18 12.1 0.1 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 ORY09453.1 - 4.1e-17 62.3 0.0 5.7e-10 39.5 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 ORY09453.1 - 1.9e-14 53.3 1.4 6.9e-05 23.1 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.7 ORY09453.1 - 1.2e-13 51.5 0.4 5.1e-13 49.4 0.4 2.2 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ORY09453.1 - 7.3e-08 32.1 0.0 0.06 13.9 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 ORY09453.1 - 3.9e-05 23.9 0.1 0.35 11.3 0.0 2.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) VWA_3_C PF18571.1 ORY09453.1 - 0.073 13.0 1.8 44 4.1 0.1 3.1 3 0 0 3 3 3 0 von Willebrand factor type A C-terminal domain Nif11 PF07862.11 ORY09453.1 - 0.09 13.1 1.8 35 4.8 0.1 3.0 3 0 0 3 3 3 0 Nif11 domain Toprim_C_rpt PF13368.6 ORY09453.1 - 0.15 12.0 1.2 14 5.8 0.1 2.4 1 1 1 2 2 2 0 Topoisomerase C-terminal repeat MT0933_antitox PF14013.6 ORY09453.1 - 0.21 11.9 3.8 7.4 7.0 0.8 2.7 1 1 1 2 2 2 0 MT0933-like antitoxin protein PALP PF00291.25 ORY09455.1 - 6.9e-60 202.9 0.2 8e-60 202.7 0.2 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme LapA_dom PF06305.11 ORY09455.1 - 0.3 10.9 0.6 0.89 9.4 0.1 1.9 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Methyltransf_28 PF02636.17 ORY09456.1 - 6.9e-38 130.8 0.0 9.9e-38 130.3 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase DUF1708 PF08101.11 ORY09457.1 - 4.4e-176 586.3 0.0 6.4e-176 585.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) CDH-cyt PF16010.5 ORY09459.1 - 2.7e-51 173.8 7.5 4.6e-51 173.1 7.5 1.4 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase SGL PF08450.12 ORY09459.1 - 0.02 14.5 0.0 0.054 13.1 0.0 1.7 2 0 0 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region Lipase_GDSL_2 PF13472.6 ORY09459.1 - 0.034 14.5 0.1 0.074 13.4 0.1 1.6 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family EF-hand_1 PF00036.32 ORY09460.1 - 3.7e-26 88.7 5.7 7.9e-07 28.2 0.1 5.3 5 1 0 5 5 5 4 EF hand EF-hand_8 PF13833.6 ORY09460.1 - 3.9e-23 81.0 1.2 3e-12 46.2 0.0 4.3 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 ORY09460.1 - 1.1e-22 78.0 2.9 0.00021 21.0 0.0 5.0 5 0 0 5 5 5 4 EF-hand domain EF-hand_7 PF13499.6 ORY09460.1 - 1.3e-21 76.8 2.1 2.8e-10 40.5 0.0 3.6 3 1 0 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 ORY09460.1 - 6.4e-19 66.5 5.0 0.00066 19.1 0.1 4.9 4 1 0 4 4 4 4 EF hand EF-hand_4 PF12763.7 ORY09460.1 - 0.03 14.2 0.7 3.1 7.8 0.0 3.0 3 0 0 3 3 3 0 Cytoskeletal-regulatory complex EF hand SRF-TF PF00319.18 ORY09462.1 - 1.1e-24 85.6 0.2 1.5e-24 85.2 0.2 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) SLAIN PF15301.6 ORY09462.1 - 0.32 10.2 5.4 0.43 9.8 5.4 1.2 1 0 0 1 1 1 0 SLAIN motif-containing family MFS_1 PF07690.16 ORY09464.1 - 6.9e-55 186.4 49.9 1.9e-50 171.7 53.0 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 ORY09464.1 - 1.7e-21 76.3 14.9 4.1e-21 75.0 14.9 1.6 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 ORY09464.1 - 6.1e-14 51.7 10.2 6.1e-14 51.7 10.2 3.9 3 1 1 4 4 4 1 Sugar (and other) transporter DUF4834 PF16118.5 ORY09464.1 - 0.06 14.3 0.1 0.06 14.3 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) TMEM208_SND2 PF05620.11 ORY09464.1 - 0.14 11.9 0.1 0.14 11.9 0.1 2.3 2 1 1 3 3 3 0 SRP-independent targeting protein 2/TMEM208 DUF1752 PF08550.10 ORY09465.1 - 1.9e-10 40.4 3.3 3.9e-10 39.4 3.3 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) ELMO_CED12 PF04727.13 ORY09466.1 - 2.1e-47 161.5 0.0 3.5e-47 160.8 0.0 1.3 1 0 0 1 1 1 1 ELMO/CED-12 family PH_12 PF16457.5 ORY09466.1 - 2.3e-38 131.8 0.0 5.2e-38 130.6 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain DUF3361 PF11841.8 ORY09466.1 - 1.8e-14 54.0 0.0 5.1e-14 52.5 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3361) Spidroin_MaSp PF11260.8 ORY09466.1 - 0.75 10.1 5.3 0.61 10.4 2.8 2.1 2 0 0 2 2 2 0 Major ampullate spidroin 1 and 2 PMAIP1 PF15150.6 ORY09468.1 - 1.1 9.1 3.0 1.5 8.8 1.2 2.2 2 0 0 2 2 2 0 Phorbol-12-myristate-13-acetate-induced HECT_2 PF09814.9 ORY09469.1 - 6.4e-106 354.4 0.1 7.4e-106 354.2 0.1 1.0 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding DUF678 PF05077.12 ORY09469.1 - 0.04 14.1 0.1 0.75 10.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF678) DZR PF12773.7 ORY09469.1 - 0.11 12.5 0.4 15 5.7 0.0 2.3 2 0 0 2 2 2 0 Double zinc ribbon Herpes_pp85 PF04637.12 ORY09469.1 - 1.6 7.1 8.4 2.8 6.2 8.4 1.3 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) 3Beta_HSD PF01073.19 ORY09470.1 - 4.7e-66 222.7 0.0 6.1e-66 222.3 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 ORY09470.1 - 1e-30 107.0 0.1 1.3e-30 106.6 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ORY09470.1 - 9.3e-22 77.9 0.1 4e-19 69.2 0.1 2.2 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 ORY09470.1 - 2.3e-13 49.9 0.2 1.7e-07 30.7 0.1 2.2 1 1 1 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 ORY09470.1 - 3.8e-13 49.2 0.0 9.6e-13 47.9 0.0 1.7 1 1 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 ORY09470.1 - 2.2e-09 36.9 0.2 4.9e-09 35.7 0.2 1.6 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 ORY09470.1 - 1.7e-08 34.5 0.0 2.7e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 ORY09470.1 - 3.1e-06 26.9 0.0 5.2e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family KR PF08659.10 ORY09470.1 - 1.6e-05 24.9 0.3 0.00048 20.1 0.3 2.5 1 1 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 ORY09470.1 - 0.021 15.1 0.0 0.044 14.0 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain UQ_con PF00179.26 ORY09471.1 - 5.8e-38 129.7 0.0 6.8e-23 80.9 0.0 2.6 2 1 0 2 2 2 2 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 ORY09471.1 - 0.0026 17.4 0.0 0.03 14.0 0.0 2.4 2 1 0 2 2 2 1 Prokaryotic E2 family B Sec5 PF15469.6 ORY09471.1 - 0.096 12.5 0.8 0.17 11.7 0.2 1.6 2 0 0 2 2 2 0 Exocyst complex component Sec5 Sybindin PF04099.12 ORY09472.1 - 5.4e-51 172.3 0.0 6.2e-51 172.1 0.0 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 ORY09472.1 - 1.1e-09 38.5 0.0 2.4e-09 37.4 0.0 1.5 2 0 0 2 2 2 1 Sedlin, N-terminal conserved region VWA_2 PF13519.6 ORY09473.1 - 2e-25 89.5 0.1 6.3e-25 87.9 0.0 1.8 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.28 ORY09473.1 - 2.4e-09 37.7 0.2 3.7e-09 37.1 0.2 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.14 ORY09473.1 - 9.7e-06 25.5 0.1 1.3e-05 25.1 0.1 1.1 1 0 0 1 1 1 1 Ssl1-like Nbl1_Borealin_N PF10444.9 ORY09474.1 - 2e-10 40.1 4.4 2e-10 40.1 4.4 1.8 2 0 0 2 2 2 1 Nbl1 / Borealin N terminal TFIIA PF03153.13 ORY09474.1 - 3.5 7.5 17.3 4.3 7.2 17.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3425 PF11905.8 ORY09483.1 - 1.2e-11 44.7 2.0 4e-11 42.9 2.0 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) Abhydrolase_6 PF12697.7 ORY09484.1 - 3.7e-21 76.8 0.0 5e-20 73.0 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORY09484.1 - 0.00091 18.6 0.1 0.0034 16.7 0.1 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ORY09484.1 - 0.012 15.2 0.0 0.03 14.0 0.0 1.6 2 0 0 2 2 2 0 alpha/beta hydrolase fold PGAP1 PF07819.13 ORY09484.1 - 0.029 14.1 0.2 0.082 12.6 0.2 1.8 1 1 0 1 1 1 0 PGAP1-like protein Peptidase_S51 PF03575.17 ORY09484.1 - 0.048 13.3 0.3 4.1 7.0 0.3 2.2 2 0 0 2 2 2 0 Peptidase family S51 SET PF00856.28 ORY09487.1 - 1.7e-06 28.6 0.0 4.9e-06 27.0 0.0 1.8 1 0 0 1 1 1 1 SET domain PHD PF00628.29 ORY09487.1 - 0.00014 21.6 10.1 0.00026 20.8 10.1 1.5 1 0 0 1 1 1 1 PHD-finger SpaA PF17802.1 ORY09487.1 - 0.054 13.8 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 Prealbumin-like fold domain DUF3398 PF11878.8 ORY09487.1 - 1.2 9.6 4.4 0.44 11.0 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3398) COesterase PF00135.28 ORY09488.1 - 5.1e-79 266.5 0.0 1e-78 265.5 0.0 1.3 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 ORY09488.1 - 4.6e-12 46.2 0.2 1.7e-11 44.4 0.2 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 ORY09488.1 - 0.069 12.6 0.1 0.12 11.8 0.1 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Methyltransf_16 PF10294.9 ORY09489.1 - 4.6e-10 39.5 0.8 1.5e-06 28.1 0.8 2.7 1 1 0 1 1 1 1 Lysine methyltransferase AMP-binding PF00501.28 ORY09490.1 - 1.5e-89 300.5 0.0 2.1e-89 300.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORY09490.1 - 0.0015 19.5 0.2 0.0037 18.2 0.2 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Xan_ur_permease PF00860.20 ORY09491.1 - 1.4e-66 224.9 31.2 2.5e-65 220.7 31.2 2.0 1 1 0 1 1 1 1 Permease family NDUF_B12 PF08122.12 ORY09491.1 - 0.43 10.7 2.0 3.3 7.8 0.2 3.1 2 1 0 2 2 2 0 NADH-ubiquinone oxidoreductase B12 subunit family 7tm_7 PF08395.12 ORY09491.1 - 2.3 7.3 9.0 0.034 13.4 1.5 1.8 2 0 0 2 2 2 0 7tm Chemosensory receptor FA_desaturase PF00487.24 ORY09493.1 - 1.7e-18 67.4 14.6 1.7e-18 67.4 14.6 1.7 1 1 0 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.28 ORY09493.1 - 2.1e-16 59.8 0.0 4.3e-16 58.8 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Tyr-DNA_phospho PF06087.12 ORY09494.1 - 3.7e-161 536.8 0.0 4.3e-161 536.5 0.0 1.0 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase C1ORF64 PF15547.6 ORY09494.1 - 0.0022 18.5 0.3 0.092 13.2 0.0 2.9 3 0 0 3 3 3 1 Steroid receptor-associated and regulated protein PLDc_2 PF13091.6 ORY09494.1 - 0.0077 16.1 0.1 0.097 12.6 0.0 2.1 2 0 0 2 2 2 1 PLD-like domain ACBP PF00887.19 ORY09495.1 - 4.5e-19 68.5 1.3 4.9e-19 68.3 1.3 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein TIP41 PF04176.13 ORY09496.1 - 1.3e-70 236.4 0.0 1.5e-70 236.1 0.0 1.1 1 0 0 1 1 1 1 TIP41-like family Peptidase_C23 PF05379.11 ORY09496.1 - 0.1 12.7 0.0 0.26 11.4 0.0 1.6 1 0 0 1 1 1 0 Carlavirus endopeptidase Pkinase PF00069.25 ORY09497.1 - 1.7e-71 240.7 0.0 2.2e-71 240.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY09497.1 - 4.1e-43 147.5 0.0 5.9e-43 147.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY09497.1 - 4.6e-09 36.0 0.0 1.7e-07 30.8 0.0 2.3 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 ORY09497.1 - 9.4e-06 24.8 0.7 3.1e-05 23.1 0.7 1.6 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 ORY09497.1 - 6.8e-05 22.3 0.2 0.00014 21.3 0.2 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 ORY09497.1 - 0.021 14.8 0.1 0.051 13.5 0.1 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 ORY09497.1 - 0.026 14.1 0.0 0.16 11.5 0.0 2.0 1 1 1 2 2 2 0 RIO1 family FTA2 PF13095.6 ORY09497.1 - 0.061 12.9 0.0 0.42 10.2 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Peptidase_M76 PF09768.9 ORY09498.1 - 1e-66 223.9 3.8 1.2e-66 223.7 3.8 1.1 1 0 0 1 1 1 1 Peptidase M76 family Peptidase_M91 PF14891.6 ORY09498.1 - 0.022 15.1 0.1 0.032 14.6 0.1 1.4 1 0 0 1 1 1 0 Effector protein Filament PF00038.21 ORY09498.1 - 0.037 13.6 0.2 0.089 12.4 0.0 1.6 2 0 0 2 2 2 0 Intermediate filament protein SprT-like PF10263.9 ORY09498.1 - 0.08 12.8 5.3 0.56 10.1 4.5 2.4 1 1 0 1 1 1 0 SprT-like family AA_kinase PF00696.28 ORY09499.1 - 5.3e-37 127.7 0.4 7.9e-37 127.1 0.4 1.2 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.20 ORY09499.1 - 1.3e-13 50.7 2.6 6.4e-07 29.2 0.2 2.9 3 0 0 3 3 3 2 PUA domain MG4 PF17789.1 ORY09499.1 - 0.16 12.1 1.2 1.9 8.7 0.1 2.3 2 0 0 2 2 2 0 Macroglobulin domain MG4 Pex14_N PF04695.13 ORY09499.1 - 0.69 10.6 10.8 9.1 6.9 0.0 3.2 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TIM21 PF08294.11 ORY09500.1 - 4.9e-42 143.2 0.0 6.3e-42 142.9 0.0 1.1 1 0 0 1 1 1 1 TIM21 Coa1 PF08695.10 ORY09500.1 - 6.2e-09 35.6 0.0 1.8e-08 34.1 0.0 1.8 1 1 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 Pex14_N PF04695.13 ORY09500.1 - 0.045 14.4 1.4 0.074 13.7 1.4 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SR-25 PF10500.9 ORY09500.1 - 0.47 10.0 9.1 0.74 9.4 9.1 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein IMUP PF15761.5 ORY09500.1 - 1.7 9.4 11.5 4.6 8.0 11.5 1.7 1 0 0 1 1 1 0 Immortalisation up-regulated protein AAA PF00004.29 ORY09501.1 - 3.3e-36 124.6 0.0 5.4e-36 123.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 ORY09501.1 - 1.7e-07 31.0 0.1 3.8e-07 29.8 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 ORY09501.1 - 2.9e-05 24.5 1.6 0.00056 20.3 0.0 2.9 2 1 0 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 ORY09501.1 - 3.2e-05 23.7 0.0 6.7e-05 22.7 0.0 1.6 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 ORY09501.1 - 6.5e-05 22.9 0.2 0.00051 20.1 0.2 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 ORY09501.1 - 6.7e-05 22.9 0.0 0.00013 22.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 ORY09501.1 - 0.00022 21.4 0.0 0.00046 20.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 ORY09501.1 - 0.00027 21.2 0.1 0.0083 16.4 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 ORY09501.1 - 0.00067 19.8 0.0 0.0013 18.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 ORY09501.1 - 0.0012 18.3 0.1 0.0023 17.4 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 ORY09501.1 - 0.0013 18.5 0.0 0.0022 17.8 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_25 PF13481.6 ORY09501.1 - 0.0014 18.2 0.1 0.036 13.6 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 ORY09501.1 - 0.0015 19.1 0.0 0.0035 17.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 ORY09501.1 - 0.0022 18.4 0.0 0.0053 17.1 0.0 1.8 1 0 0 1 1 1 1 RNA helicase TniB PF05621.11 ORY09501.1 - 0.0034 16.8 0.0 2.8 7.3 0.0 2.6 1 1 1 2 2 2 2 Bacterial TniB protein AAA_24 PF13479.6 ORY09501.1 - 0.0037 17.0 0.0 0.016 15.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 ORY09501.1 - 0.0056 16.6 0.0 0.017 15.0 0.0 1.8 2 0 0 2 2 2 1 NACHT domain AAA_28 PF13521.6 ORY09501.1 - 0.0089 16.3 0.0 0.02 15.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.6 ORY09501.1 - 0.02 15.0 0.0 0.046 13.8 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Rad17 PF03215.15 ORY09501.1 - 0.022 14.7 0.1 0.068 13.1 0.1 1.6 1 1 1 2 2 2 0 Rad17 P-loop domain Parvo_NS1 PF01057.17 ORY09501.1 - 0.026 13.6 0.0 0.044 12.9 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.26 ORY09501.1 - 0.034 13.9 0.0 0.073 12.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ABC_tran PF00005.27 ORY09501.1 - 0.042 14.4 0.1 0.11 13.1 0.0 1.7 2 0 0 2 2 1 0 ABC transporter DUF815 PF05673.13 ORY09501.1 - 0.072 12.2 0.0 0.17 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 ORY09501.1 - 0.076 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region CPT PF07931.12 ORY09501.1 - 0.081 12.8 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein ATPase_2 PF01637.18 ORY09501.1 - 0.086 12.7 0.0 0.27 11.1 0.0 1.7 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea TsaE PF02367.17 ORY09501.1 - 0.13 12.3 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Viral_helicase1 PF01443.18 ORY09501.1 - 0.14 11.8 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Guanylate_kin PF00625.21 ORY09501.1 - 0.16 11.7 0.0 1.8 8.2 0.0 2.6 2 1 1 3 3 3 0 Guanylate kinase Coatomer_WDAD PF04053.14 ORY09502.1 - 6.9e-172 572.5 0.0 1.4e-171 571.5 0.0 1.5 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.32 ORY09502.1 - 5.1e-37 125.2 2.1 2.8e-06 27.9 0.0 7.8 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.8 ORY09502.1 - 0.00045 19.0 2.0 0.15 10.7 0.1 3.6 2 2 1 3 3 3 2 Nucleoporin Nup120/160 MetallophosC PF16370.5 ORY09502.1 - 0.0096 16.2 0.1 0.053 13.8 0.0 2.2 2 1 0 2 2 2 1 C terminal of Calcineurin-like phosphoesterase BBS2_Mid PF14783.6 ORY09502.1 - 0.013 15.6 0.0 3.1 7.9 0.0 3.6 2 1 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region TPR_4 PF07721.14 ORY09502.1 - 5.8 7.8 5.9 30 5.6 0.2 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat T5orf172 PF10544.9 ORY09504.1 - 3.8e-15 56.3 0.8 6.1e-15 55.6 0.2 1.6 2 0 0 2 2 2 1 T5orf172 domain MUG113 PF13455.6 ORY09504.1 - 8.4e-07 29.6 0.3 1.8e-06 28.5 0.3 1.6 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 PRIMA1 PF16101.5 ORY09504.1 - 0.14 12.2 1.7 0.2 11.7 1.7 1.3 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Glyco_hydro_75 PF07335.11 ORY09505.1 - 7e-33 114.2 0.2 8.2e-33 114.0 0.2 1.1 1 0 0 1 1 1 1 Fungal chitosanase of glycosyl hydrolase group 75 T5orf172 PF10544.9 ORY09506.1 - 2.1e-14 53.9 0.9 4.9e-14 52.7 0.9 1.6 1 0 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 ORY09506.1 - 9.3e-09 35.8 0.7 1.8e-08 34.9 0.7 1.5 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 HTH_Tnp_4 PF13613.6 ORY09506.1 - 0.073 12.8 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease ABC_tran PF00005.27 ORY09507.1 - 9.1e-46 155.8 0.0 3.9e-28 98.7 0.1 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 ORY09507.1 - 1.1e-40 140.0 29.9 1.5e-24 87.1 14.0 3.5 4 0 0 4 4 4 3 ABC transporter transmembrane region SMC_N PF02463.19 ORY09507.1 - 2e-13 50.3 1.1 2e-06 27.4 0.1 4.2 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 ORY09507.1 - 3.2e-07 30.9 0.1 0.043 14.2 0.1 3.2 3 0 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 ORY09507.1 - 4.9e-07 30.1 0.0 0.053 13.8 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_21 PF13304.6 ORY09507.1 - 1.6e-06 28.2 0.4 0.065 13.0 0.0 4.3 3 1 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 ORY09507.1 - 2e-05 24.2 1.3 0.013 15.3 0.3 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.6 ORY09507.1 - 4.6e-05 23.1 0.1 0.0012 18.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 ORY09507.1 - 0.00023 20.3 0.3 0.13 11.3 0.1 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein DUF87 PF01935.17 ORY09507.1 - 0.0017 18.5 0.5 0.0017 18.5 0.5 2.3 2 1 0 2 2 2 1 Helicase HerA, central domain FtsK_SpoIIIE PF01580.18 ORY09507.1 - 0.0024 17.3 0.1 0.046 13.1 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_23 PF13476.6 ORY09507.1 - 0.0034 17.9 8.2 0.0076 16.8 0.1 2.7 3 0 0 3 3 2 1 AAA domain MMR_HSR1 PF01926.23 ORY09507.1 - 0.0088 16.1 0.1 1.3 9.1 0.1 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase NACHT PF05729.12 ORY09507.1 - 0.016 15.1 0.0 8.1 6.3 0.1 2.8 2 0 0 2 2 2 0 NACHT domain RsgA_GTPase PF03193.16 ORY09507.1 - 0.046 13.6 0.0 4.6 7.1 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase ATPase_2 PF01637.18 ORY09507.1 - 0.053 13.4 0.1 0.87 9.5 0.0 2.5 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea Pox_A32 PF04665.12 ORY09507.1 - 0.092 12.2 0.4 0.45 9.9 0.0 2.0 2 0 0 2 2 2 0 Poxvirus A32 protein TrwB_AAD_bind PF10412.9 ORY09507.1 - 0.11 11.4 0.6 0.59 9.0 0.1 2.1 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain ABC_ATPase PF09818.9 ORY09507.1 - 0.13 11.0 1.1 0.46 9.2 0.1 2.1 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_7 PF12775.7 ORY09507.1 - 0.2 11.1 0.2 14 5.1 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_15 PF13175.6 ORY09507.1 - 0.22 11.2 0.1 7.8 6.1 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain Dynamin_N PF00350.23 ORY09507.1 - 1.1 9.3 3.0 25 4.9 0.1 2.8 3 0 0 3 3 3 0 Dynamin family R3H-assoc PF13902.6 ORY09508.1 - 9.7e-20 71.3 2.8 3.4e-19 69.6 2.8 1.9 1 1 0 1 1 1 1 R3H-associated N-terminal domain Peptidase_M28 PF04389.17 ORY09509.1 - 2.5e-31 108.9 0.0 3.4e-31 108.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 ORY09509.1 - 2.2e-07 30.8 0.0 4.3e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_C14 PF00656.22 ORY09510.1 - 0.00028 20.9 0.0 0.00082 19.4 0.0 1.7 1 1 0 1 1 1 1 Caspase domain Raptor_N PF14538.6 ORY09510.1 - 0.086 12.8 0.3 0.24 11.3 0.0 1.8 2 0 0 2 2 2 0 Raptor N-terminal CASPase like domain Cytochrom_B_C PF00032.17 ORY09511.1 - 0.033 14.5 1.6 0.055 13.8 1.6 1.4 1 0 0 1 1 1 0 Cytochrome b(C-terminal)/b6/petD Piezo_RRas_bdg PF12166.8 ORY09511.1 - 0.057 12.7 0.7 0.082 12.2 0.7 1.2 1 0 0 1 1 1 0 Piezo non-specific cation channel, R-Ras-binding domain PDR_CDR PF06422.12 ORY09511.1 - 0.33 10.9 4.6 2.9 7.8 0.6 2.4 1 1 1 2 2 2 0 CDR ABC transporter DUF3433 PF11915.8 ORY09512.1 - 2.7e-18 66.2 0.3 6.6e-18 65.0 0.3 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3433) NOT2_3_5 PF04153.18 ORY09513.1 - 9.9e-23 80.7 0.1 9.9e-23 80.7 0.1 1.6 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family bZIP_1 PF00170.21 ORY09514.1 - 1.7e-06 28.0 3.8 2.6e-06 27.4 3.8 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 ORY09514.1 - 3.7e-05 23.7 10.3 0.00017 21.6 10.3 1.9 1 1 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 ORY09514.1 - 0.00015 22.2 5.7 0.00021 21.7 5.7 1.1 1 0 0 1 1 1 1 bZIP Maf transcription factor WD40_alt PF14077.6 ORY09514.1 - 0.0008 19.2 0.4 0.0014 18.4 0.4 1.4 1 1 0 1 1 1 1 Alternative WD40 repeat motif TPD52 PF04201.15 ORY09514.1 - 0.0013 18.4 0.6 0.0018 17.9 0.6 1.3 1 0 0 1 1 1 1 Tumour protein D52 family BST2 PF16716.5 ORY09514.1 - 0.0034 17.9 1.2 0.0044 17.6 1.2 1.3 1 0 0 1 1 1 1 Bone marrow stromal antigen 2 CENP-F_leu_zip PF10473.9 ORY09514.1 - 0.012 15.6 0.5 0.017 15.2 0.5 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMF_DNA_bd PF12329.8 ORY09514.1 - 0.068 13.2 1.4 0.089 12.8 1.4 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DivIC PF04977.15 ORY09514.1 - 0.15 11.8 1.3 0.21 11.4 0.8 1.5 1 1 0 1 1 1 0 Septum formation initiator Bap31_Bap29_C PF18035.1 ORY09514.1 - 0.18 11.9 1.6 0.43 10.6 0.4 2.0 1 1 1 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain NUDE_C PF04880.13 ORY09514.1 - 0.44 11.0 10.8 0.55 10.7 1.2 2.1 1 1 1 2 2 2 0 NUDE protein, C-terminal conserved region MRP-L47 PF06984.13 ORY09515.1 - 2.5e-15 56.4 0.2 4e-15 55.7 0.2 1.4 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) GDI PF00996.18 ORY09516.1 - 3.5e-192 638.7 0.0 4e-192 638.5 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.6 ORY09516.1 - 0.0083 16.3 0.0 0.019 15.2 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 ORY09516.1 - 0.13 12.8 0.2 0.44 11.1 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase PigN PF04987.14 ORY09517.1 - 1.4e-164 548.4 30.2 1.4e-164 548.4 30.2 1.8 2 0 0 2 2 2 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.22 ORY09517.1 - 1.4e-11 44.6 3.0 4.4e-10 39.7 2.9 2.2 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 ORY09517.1 - 8.8e-09 35.2 0.1 1.8e-08 34.2 0.1 1.4 1 1 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.18 ORY09517.1 - 3.3e-05 23.4 0.0 5.4e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Baculo_ODV-E27 PF05314.11 ORY09517.1 - 0.028 13.6 0.0 0.05 12.8 0.0 1.3 1 0 0 1 1 1 0 Baculovirus occlusion-derived virus envelope protein EC27 PsaF PF17550.2 ORY09517.1 - 0.35 10.4 2.7 0.47 10.0 0.2 2.5 3 0 0 3 3 3 0 Family of unknown function BLOC1_2 PF10046.9 ORY09518.1 - 0.04 14.2 1.3 0.072 13.4 0.5 1.8 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Vps5 PF09325.10 ORY09518.1 - 0.062 12.8 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Vps5 C terminal like KfrA_N PF11740.8 ORY09518.1 - 0.073 13.7 4.5 1.9 9.2 2.0 2.9 2 1 1 3 3 3 0 Plasmid replication region DNA-binding N-term Rx_N PF18052.1 ORY09518.1 - 0.095 13.0 0.9 0.3 11.4 0.3 2.0 2 0 0 2 2 2 0 Rx N-terminal domain T2SSM PF04612.12 ORY09518.1 - 0.11 12.5 0.3 0.11 12.5 0.3 1.7 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M TMF_TATA_bd PF12325.8 ORY09518.1 - 0.13 12.5 0.8 0.67 10.2 0.2 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Prefoldin PF02996.17 ORY09518.1 - 0.52 10.2 2.9 0.31 11.0 0.2 1.9 3 0 0 3 3 3 0 Prefoldin subunit Coleoptericin PF06286.11 ORY09518.1 - 0.53 10.4 4.2 1.2 9.3 2.3 2.1 2 0 0 2 2 2 0 Coleoptericin RNA_pol_I_TF PF04090.12 ORY09520.1 - 1.8e-11 43.9 0.0 6e-11 42.2 0.0 1.7 1 1 0 1 1 1 1 RNA polymerase I specific initiation factor zf-RING_2 PF13639.6 ORY09521.1 - 1.7e-11 44.3 8.0 2.5e-11 43.7 8.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 ORY09521.1 - 2.7e-09 37.2 4.6 4.5e-09 36.4 4.6 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 ORY09521.1 - 6.3e-07 29.1 7.0 1e-06 28.5 7.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORY09521.1 - 4.7e-06 26.4 6.6 7e-06 25.8 6.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 ORY09521.1 - 1.6e-05 24.5 6.3 2.8e-05 23.7 6.3 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-ANAPC11 PF12861.7 ORY09521.1 - 2.4e-05 24.3 0.8 3.9e-05 23.6 0.8 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 ORY09521.1 - 6.9e-05 22.7 5.5 0.0001 22.2 5.5 1.3 1 0 0 1 1 1 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 ORY09521.1 - 0.0004 20.0 5.2 0.00064 19.3 5.2 1.2 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 ORY09521.1 - 0.00059 19.6 5.5 0.001 18.9 5.5 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 ORY09521.1 - 0.002 18.1 6.9 0.0039 17.2 6.9 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 ORY09521.1 - 0.0036 17.1 4.9 0.0056 16.5 4.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 ORY09521.1 - 0.21 11.4 5.8 0.39 10.5 5.8 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_5 PF17121.5 ORY09521.1 - 0.3 11.0 2.8 0.51 10.3 2.8 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 ORY09521.1 - 0.37 11.0 4.4 0.67 10.2 4.4 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.7 ORY09521.1 - 0.49 10.5 7.6 0.81 9.9 7.6 1.4 1 0 0 1 1 1 0 RING-variant domain zf-RING-like PF08746.11 ORY09521.1 - 2.6 8.4 5.2 4.5 7.7 5.2 1.4 1 0 0 1 1 1 0 RING-like domain zf-C3HC4_4 PF15227.6 ORY09521.1 - 3.4 7.9 5.9 8.9 6.6 6.0 1.7 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Fungal_trans_2 PF11951.8 ORY09524.1 - 1.1e-09 37.6 0.3 1.9e-09 36.8 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY09524.1 - 1.7e-07 31.3 9.3 2.8e-07 30.6 9.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SHOCT PF09851.9 ORY09524.1 - 0.026 14.3 0.1 0.026 14.3 0.1 2.0 2 0 0 2 2 2 0 Short C-terminal domain BAR_2 PF10455.9 ORY09525.1 - 4.6e-63 213.0 0.1 6.6e-63 212.5 0.1 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 ORY09525.1 - 6.7e-19 68.5 1.7 6.5e-18 65.2 1.7 2.1 1 1 0 1 1 1 1 BAR domain BAR_3 PF16746.5 ORY09525.1 - 0.00063 19.5 1.0 0.046 13.4 0.0 2.6 2 1 1 3 3 3 2 BAR domain of APPL family AIG2_2 PF13772.6 ORY09526.1 - 1.6e-06 28.4 1.5 8.3e-06 26.1 0.2 2.4 2 1 0 2 2 2 1 AIG2-like family GGACT PF06094.12 ORY09526.1 - 7.4e-06 26.6 0.1 1.4e-05 25.7 0.1 1.5 1 1 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like PHP PF02811.19 ORY09527.1 - 7.3e-15 55.7 0.0 1.2e-14 55.0 0.0 1.4 1 0 0 1 1 1 1 PHP domain FKBP_C PF00254.28 ORY09528.1 - 2.8e-21 75.6 0.0 3.4e-21 75.4 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase TMEM154 PF15102.6 ORY09531.1 - 0.0011 18.8 0.1 0.0028 17.5 0.1 1.6 1 0 0 1 1 1 1 TMEM154 protein family DUF4366 PF14283.6 ORY09531.1 - 0.15 12.1 0.0 0.33 11.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) ACPS PF01648.20 ORY09532.1 - 3.8e-07 30.2 0.1 6.5e-07 29.5 0.1 1.4 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily 4PPT_N PF17837.1 ORY09532.1 - 0.0024 18.0 0.6 1 9.5 0.0 2.4 2 0 0 2 2 2 2 4'-phosphopantetheinyl transferase N-terminal domain Retrotran_gag_2 PF14223.6 ORY09533.1 - 0.0084 15.8 0.1 0.026 14.2 0.1 1.7 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type Aminotran_1_2 PF00155.21 ORY09534.1 - 1.2e-82 278.1 0.0 1.3e-82 277.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Syntaxin-18_N PF10496.9 ORY09536.1 - 3.2e-10 40.1 1.9 3e-09 37.0 0.1 3.0 2 1 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.19 ORY09536.1 - 9.6e-05 22.3 0.0 0.0005 20.0 0.0 2.2 2 0 0 2 2 2 1 SNARE domain ATP-grasp_2 PF08442.10 ORY09536.1 - 0.011 15.3 0.9 0.029 13.9 0.9 1.6 1 0 0 1 1 1 0 ATP-grasp domain Phage_int_SAM_2 PF12834.7 ORY09536.1 - 0.078 13.7 0.7 32 5.3 0.0 3.1 3 0 0 3 3 3 0 Phage integrase, N-terminal KELK PF15796.5 ORY09536.1 - 3.6 8.1 8.7 1.8 9.1 1.7 3.3 2 1 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase MFS_1 PF07690.16 ORY09537.1 - 6e-42 143.8 23.5 6e-42 143.8 23.5 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY09537.1 - 6e-06 25.4 12.7 6e-06 25.4 12.7 2.8 2 1 1 3 3 3 1 Sugar (and other) transporter MFS_5 PF05631.14 ORY09537.1 - 0.027 13.4 6.5 0.011 14.7 2.4 2.0 2 0 0 2 2 2 0 Sugar-tranasporters, 12 TM OATP PF03137.20 ORY09537.1 - 1 7.6 6.8 1.9 6.7 2.0 2.6 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Ran_BP1 PF00638.18 ORY09538.1 - 7e-17 61.8 0.0 1.1e-16 61.2 0.0 1.3 1 0 0 1 1 1 1 RanBP1 domain Yip1 PF04893.17 ORY09539.1 - 2.6e-12 46.8 14.0 3.9e-12 46.2 13.8 1.5 1 1 0 1 1 1 1 Yip1 domain DUF1282 PF06930.12 ORY09539.1 - 0.4 10.4 7.4 0.73 9.6 7.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1282) DUF2070 PF09843.9 ORY09539.1 - 2.4 6.4 7.8 2.9 6.1 7.8 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) GalP_UDP_transf PF01087.22 ORY09540.1 - 2.7e-67 226.7 0.4 1.3e-65 221.3 0.1 2.5 2 1 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.17 ORY09540.1 - 2.1e-59 200.0 0.1 6.8e-59 198.3 0.1 1.7 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, C-terminal domain DUF4921 PF16268.5 ORY09540.1 - 0.13 11.0 0.0 6.3 5.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4921) Erg28 PF03694.13 ORY09541.1 - 6.9e-46 155.2 0.5 8.3e-46 154.9 0.5 1.1 1 0 0 1 1 1 1 Erg28 like protein Ribosomal_S17_N PF16205.5 ORY09542.1 - 5.8e-33 113.1 0.1 9.2e-33 112.4 0.1 1.3 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 ORY09542.1 - 1.7e-25 88.9 0.1 3.4e-25 87.9 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S17 adh_short PF00106.25 ORY09543.1 - 4.1e-37 127.5 0.0 5.8e-37 127.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY09543.1 - 2.3e-23 83.0 0.0 3.1e-23 82.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.15 ORY09543.1 - 0.0004 19.6 0.0 0.00054 19.2 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 ORY09543.1 - 0.0024 17.8 0.0 0.0097 15.8 0.0 1.8 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 ORY09543.1 - 0.12 11.8 0.1 0.21 11.0 0.1 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF937 PF06078.11 ORY09544.1 - 0.25 11.9 4.2 0.26 11.9 3.1 1.6 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF937) Beta-prism_lec PF16458.5 ORY09544.1 - 0.28 11.2 5.1 0.18 11.8 1.3 2.4 2 1 0 2 2 2 0 Beta-prism lectin YbaB_DNA_bd PF02575.16 ORY09544.1 - 1.6 9.0 4.8 2.7 8.3 0.1 2.5 2 1 1 3 3 3 0 YbaB/EbfC DNA-binding family Chordopox_RPO7 PF05864.12 ORY09545.1 - 0.039 14.2 0.1 0.078 13.2 0.0 1.6 2 0 0 2 2 2 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) p450 PF00067.22 ORY09563.1 - 1.4e-52 179.0 0.0 2.1e-52 178.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.18 ORY09564.1 - 2.1e-09 36.8 0.1 3.9e-09 35.9 0.1 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY09564.1 - 3.5e-09 36.6 6.4 7.4e-09 35.6 6.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_3 PF01494.19 ORY09565.1 - 6.6e-15 55.2 0.0 8.9e-15 54.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 ORY09565.1 - 6.2e-05 23.1 0.1 0.00014 22.0 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ORY09565.1 - 0.00016 21.0 0.2 0.014 14.6 0.1 2.0 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORY09565.1 - 0.00022 21.7 1.4 0.0025 18.3 0.1 2.8 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 ORY09565.1 - 0.0043 16.3 0.1 0.0075 15.5 0.1 1.4 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 ORY09565.1 - 0.0058 16.3 0.4 0.016 14.8 0.2 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 ORY09565.1 - 0.017 14.2 0.3 0.031 13.4 0.3 1.4 1 0 0 1 1 1 0 FAD binding domain CoA_transf_3 PF02515.17 ORY09565.1 - 0.072 12.2 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 CoA-transferase family III FAD_oxidored PF12831.7 ORY09565.1 - 0.075 12.4 0.0 0.098 12.0 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 ORY09565.1 - 0.12 11.6 0.0 11 5.2 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Xan_ur_permease PF00860.20 ORY09566.1 - 2.6e-46 158.1 31.8 1e-45 156.2 31.8 1.7 1 1 0 1 1 1 1 Permease family Amidohydro_1 PF01979.20 ORY09567.1 - 2.6e-59 201.3 0.2 4.5e-59 200.5 0.1 1.4 1 1 1 2 2 2 1 Amidohydrolase family Amidohydro_3 PF07969.11 ORY09567.1 - 7.5e-17 61.9 0.2 2.2e-12 47.2 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family A_deaminase PF00962.22 ORY09567.1 - 0.0045 16.4 0.0 0.22 10.8 0.0 2.2 2 0 0 2 2 2 2 Adenosine/AMP deaminase DUF2771 PF10969.8 ORY09567.1 - 0.16 12.0 0.0 0.37 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2771) Cep3 PF16846.5 ORY09568.1 - 0.0005 18.7 0.0 0.00072 18.2 0.0 1.1 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit B Zn_clus PF00172.18 ORY09569.1 - 1.8e-08 34.4 10.0 2.8e-08 33.7 10.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DIOX_N PF14226.6 ORY09570.1 - 5.2e-17 62.7 0.0 1.1e-16 61.7 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 ORY09570.1 - 8.3e-15 55.1 0.0 1.5e-14 54.3 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily FAD_binding_3 PF01494.19 ORY09571.1 - 0.068 12.4 0.0 0.13 11.4 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain CMD PF02627.20 ORY09572.1 - 8.6e-05 22.5 0.0 0.00012 22.1 0.0 1.2 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family MFS_1 PF07690.16 ORY09573.1 - 7.3e-32 110.7 44.7 1.4e-31 109.8 44.7 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY09573.1 - 1.8e-11 43.6 10.4 1.8e-11 43.6 10.4 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter adh_short_C2 PF13561.6 ORY09576.1 - 8.4e-58 195.7 6.0 3.3e-57 193.7 6.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY09576.1 - 9.8e-44 149.2 3.4 2.5e-43 147.8 3.4 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORY09576.1 - 3e-09 37.1 0.6 4.9e-09 36.3 0.6 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 ORY09576.1 - 0.0049 16.0 1.1 0.0079 15.4 1.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein ArAE_1 PF06081.11 ORY09576.1 - 0.026 14.7 0.1 0.043 14.0 0.1 1.2 1 0 0 1 1 1 0 Aromatic acid exporter family member 1 HHH_5 PF14520.6 ORY09576.1 - 0.82 10.3 3.4 1.3 9.6 0.4 2.7 3 0 0 3 3 3 0 Helix-hairpin-helix domain Ketoacyl-synt_C PF02801.22 ORY09577.1 - 4.6e-29 100.8 0.6 7.2e-29 100.2 0.6 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ketoacyl-synt PF00109.26 ORY09577.1 - 4e-24 85.6 0.1 1.9e-14 53.9 0.0 2.5 2 1 1 3 3 3 2 Beta-ketoacyl synthase, N-terminal domain KAsynt_C_assoc PF16197.5 ORY09577.1 - 4.4e-09 36.8 0.0 1e-08 35.6 0.0 1.6 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension KR PF08659.10 ORY09578.1 - 4.1e-33 114.8 3.3 5.6e-31 107.8 3.2 2.9 2 1 0 2 2 2 1 KR domain PS-DH PF14765.6 ORY09578.1 - 3.5e-25 88.9 0.0 5.5e-25 88.2 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Methyltransf_12 PF08242.12 ORY09578.1 - 2.3e-18 66.8 0.0 8.3e-18 65.0 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY09578.1 - 5.3e-13 49.1 0.0 1.2e-12 47.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY09578.1 - 4.8e-11 43.2 0.1 4.5e-10 40.1 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY09578.1 - 3.3e-10 40.5 0.0 1.4e-09 38.5 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.6 ORY09578.1 - 6.8e-10 40.1 0.0 9.5e-09 36.4 0.0 2.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 ORY09578.1 - 1.1e-09 38.4 0.0 3.1e-09 36.9 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_31 PF13847.6 ORY09578.1 - 4.1e-08 33.2 0.0 9.7e-08 31.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORY09578.1 - 4.9e-07 29.3 0.0 8.5e-07 28.5 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family adh_short PF00106.25 ORY09578.1 - 2.7e-05 23.7 0.8 0.0002 20.9 0.8 2.3 1 1 0 1 1 1 1 short chain dehydrogenase Methyltransf_33 PF10017.9 ORY09578.1 - 0.00094 18.4 0.0 0.0018 17.5 0.0 1.4 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent adh_short_C2 PF13561.6 ORY09578.1 - 0.0026 17.3 0.2 0.047 13.2 0.1 2.4 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase 3Beta_HSD PF01073.19 ORY09578.1 - 0.0086 15.1 0.1 0.02 13.9 0.0 1.6 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Shikimate_DH PF01488.20 ORY09578.1 - 0.026 14.6 0.0 0.065 13.3 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Methyltransf_24 PF13578.6 ORY09578.1 - 0.041 14.9 0.0 0.14 13.2 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Polysacc_synt_2 PF02719.15 ORY09578.1 - 0.041 13.0 0.0 0.071 12.2 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein ADH_N PF08240.12 ORY09578.1 - 0.054 13.4 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain Methyltransf_28 PF02636.17 ORY09578.1 - 0.06 13.0 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase DUF1304 PF06993.12 ORY09579.1 - 0.075 13.0 2.8 0.14 12.2 2.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1304) DUF2374 PF09574.10 ORY09579.1 - 0.18 11.7 1.8 0.5 10.2 1.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (Duf2374) Wbp11 PF09429.10 ORY09579.1 - 1.4 9.4 3.3 4.5 7.8 3.3 1.8 1 1 0 1 1 1 0 WW domain binding protein 11 Asp_protease_2 PF13650.6 ORY09581.1 - 1.9e-10 41.2 0.0 6.7e-05 23.5 0.0 2.5 2 0 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 ORY09581.1 - 1.1e-08 35.6 0.0 0.00075 20.0 0.0 2.6 3 0 0 3 3 3 2 gag-polyprotein putative aspartyl protease zf-C2H2 PF00096.26 ORY09582.1 - 2.3e-15 56.1 54.2 0.051 14.0 0.2 10.5 10 0 0 10 10 10 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY09582.1 - 1.4e-14 53.6 48.8 0.012 16.3 0.1 10.4 10 0 0 10 10 10 6 C2H2-type zinc finger zf-met PF12874.7 ORY09582.1 - 9.2e-11 41.8 44.9 0.088 13.2 0.5 9.0 9 0 0 9 9 9 7 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 ORY09582.1 - 6.6e-05 23.1 41.2 0.08 13.3 0.2 9.5 8 2 2 10 10 10 4 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 ORY09582.1 - 0.0015 18.2 5.5 0.02 14.6 0.4 4.3 4 0 0 4 4 4 1 C2H2-type zinc-finger domain zf-C2H2_2 PF12756.7 ORY09582.1 - 0.0021 18.3 41.8 0.014 15.7 4.6 7.4 2 1 5 7 7 7 2 C2H2 type zinc-finger (2 copies) Elongin_A PF06881.11 ORY09582.1 - 0.2 12.2 1.1 11 6.6 0.8 2.4 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A zf-C2H2_8 PF15909.5 ORY09582.1 - 0.68 10.3 27.4 2.6 8.4 2.4 5.3 3 2 2 5 5 5 0 C2H2-type zinc ribbon Vps36-NZF-N PF16988.5 ORY09582.1 - 1.1 8.7 11.9 13 5.3 1.2 3.7 3 0 0 3 3 3 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain SipA PF09052.10 ORY09583.1 - 0.034 13.8 0.7 0.054 13.1 0.7 1.3 1 0 0 1 1 1 0 SipA N-terminal domain TFB6 PF17110.5 ORY09583.1 - 0.19 11.5 1.4 0.75 9.5 1.4 2.0 1 1 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH RRF PF01765.19 ORY09583.1 - 0.19 11.7 0.1 0.19 11.7 0.1 3.1 3 1 1 4 4 4 0 Ribosome recycling factor DUF1497 PF07384.11 ORY09583.1 - 0.73 10.3 2.8 1.6 9.2 0.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1497) Homeodomain PF00046.29 ORY09584.1 - 2.9e-10 39.8 0.0 6.6e-10 38.7 0.0 1.7 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 ORY09584.1 - 4.4e-07 29.7 0.0 1.2e-06 28.3 0.0 1.8 1 0 0 1 1 1 1 Homeobox KN domain zf-C2H2 PF00096.26 ORY09584.1 - 0.00042 20.6 5.9 2.8 8.6 1.6 4.6 3 1 1 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY09584.1 - 0.055 14.3 14.4 1.7 9.7 0.2 4.6 4 1 0 4 4 4 0 C2H2-type zinc finger Fungal_trans_2 PF11951.8 ORY09585.1 - 1.2e-35 123.1 3.9 1.7e-35 122.6 3.9 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 ORY09586.1 - 3.1e-29 102.0 31.2 3.1e-29 102.0 31.2 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.18 ORY09588.1 - 8.3e-19 67.6 0.0 1.7e-18 66.6 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY09589.1 - 5.8e-08 32.7 13.3 8.4e-08 32.2 13.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pox_A_type_inc PF04508.12 ORY09589.1 - 0.03 14.2 0.1 0.073 13.0 0.1 1.7 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat Tegument_dsDNA PF12818.7 ORY09590.1 - 0.049 12.8 0.4 0.061 12.5 0.4 1.1 1 0 0 1 1 1 0 dsDNA viral tegument protein Hamartin PF04388.12 ORY09590.1 - 0.052 12.2 3.8 0.059 12.0 3.8 1.0 1 0 0 1 1 1 0 Hamartin protein Fungal_trans PF04082.18 ORY09591.1 - 1.1e-14 54.1 1.1 1.7e-14 53.5 1.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY09591.1 - 7.1e-08 32.5 9.9 1.1e-07 31.9 9.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain VPS9 PF02204.18 ORY09592.1 - 1.9e-26 92.3 0.0 3.1e-26 91.6 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 ORY09592.1 - 3.5e-14 52.9 0.0 1e-13 51.4 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF5601) CUE PF02845.16 ORY09592.1 - 1.3e-07 31.1 0.0 1.8e-06 27.5 0.0 2.3 2 0 0 2 2 2 1 CUE domain Asn_synthase PF00733.21 ORY09593.1 - 3e-15 56.8 0.4 0.00012 21.8 0.1 3.1 2 1 1 3 3 3 3 Asparagine synthase GATase_7 PF13537.6 ORY09593.1 - 3e-05 23.9 0.0 9.1e-05 22.4 0.0 1.8 1 1 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 ORY09593.1 - 0.086 12.3 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Aluminium induced protein GHBP PF12772.7 ORY09594.1 - 0.1 12.1 0.2 0.14 11.6 0.2 1.2 1 0 0 1 1 1 0 Growth hormone receptor binding DUF4202 PF13875.6 ORY09595.1 - 1e-77 260.3 0.9 1.1e-77 260.1 0.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4202) Cu-oxidase_2 PF07731.14 ORY09597.1 - 1.1e-43 148.3 6.6 1.3e-38 131.8 0.3 3.4 3 0 0 3 3 3 3 Multicopper oxidase Cu-oxidase_3 PF07732.15 ORY09597.1 - 2.4e-39 134.0 0.8 2.4e-39 134.0 0.8 3.5 4 1 0 4 4 4 2 Multicopper oxidase Cu-oxidase PF00394.22 ORY09597.1 - 2.5e-36 125.2 3.0 5.6e-34 117.6 0.9 3.1 3 0 0 3 3 3 1 Multicopper oxidase p450 PF00067.22 ORY09598.1 - 7.8e-45 153.5 0.0 1.4e-28 99.9 0.0 2.3 2 1 0 2 2 2 2 Cytochrome P450 DUF3237 PF11578.8 ORY09599.1 - 1.2e-41 142.0 0.1 1.4e-41 141.8 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) Rrn6 PF10214.9 ORY09601.1 - 1e-186 623.1 0.0 1.2e-186 622.9 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor Spindle_Spc25 PF08234.12 ORY09602.1 - 2.1e-26 91.9 0.2 4.7e-26 90.8 0.2 1.6 1 0 0 1 1 1 1 Chromosome segregation protein Spc25 HEPN_AbiU2 PF18734.1 ORY09602.1 - 0.016 14.7 0.7 0.016 14.7 0.7 1.9 2 0 0 2 2 2 0 AbiU2 TMPIT PF07851.13 ORY09602.1 - 1.9 7.6 6.8 2.8 7.1 6.8 1.2 1 0 0 1 1 1 0 TMPIT-like protein HA2 PF04408.23 ORY09603.1 - 9.8e-18 64.4 0.8 2e-17 63.4 0.8 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 ORY09603.1 - 2.7e-14 53.3 0.0 5.3e-14 52.3 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 ORY09603.1 - 2.1e-12 47.4 0.0 4.4e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 ORY09603.1 - 0.017 14.9 0.1 0.033 14.0 0.1 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase GMC_oxred_N PF00732.19 ORY09605.1 - 7.7e-48 163.4 0.0 1.1e-47 162.8 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 ORY09605.1 - 1.1e-34 120.1 0.1 1.8e-34 119.3 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 ORY09605.1 - 2.3e-10 40.6 1.0 8.1e-10 38.8 0.9 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ORY09605.1 - 1.9e-05 24.1 0.0 0.0054 16.0 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ORY09605.1 - 0.0012 18.0 3.4 0.28 10.2 2.2 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 ORY09605.1 - 0.0054 15.8 0.4 0.0091 15.1 0.4 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 ORY09605.1 - 0.0073 15.6 3.1 1.9 7.6 2.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 ORY09605.1 - 0.019 13.9 0.1 0.035 13.0 0.1 1.4 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_8 PF13450.6 ORY09605.1 - 0.067 13.4 4.5 0.22 11.8 3.6 2.4 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 ORY09605.1 - 0.17 12.5 1.8 7.9 7.1 0.9 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ORY09605.1 - 0.31 9.7 2.9 0.21 10.3 1.0 1.6 2 0 0 2 2 2 0 HI0933-like protein AA_permease_2 PF13520.6 ORY09606.1 - 1.2e-51 176.0 56.8 1.5e-51 175.6 56.8 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ORY09606.1 - 3.3e-24 85.3 47.9 4.4e-24 84.9 47.9 1.0 1 0 0 1 1 1 1 Amino acid permease YlaH PF14036.6 ORY09606.1 - 0.034 14.5 1.6 0.034 14.5 1.6 3.8 3 1 0 3 3 3 0 YlaH-like protein Acetyltransf_1 PF00583.25 ORY09608.1 - 2.7e-08 34.0 0.0 5.8e-07 29.8 0.0 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ORY09608.1 - 4.9e-06 26.9 0.0 1.3e-05 25.5 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 ORY09608.1 - 0.0042 17.2 0.1 0.021 14.9 0.0 2.0 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase Acetyltransf_10 PF13673.7 ORY09608.1 - 0.0048 16.8 0.0 0.011 15.7 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain MMS19_C PF12460.8 ORY09609.1 - 0.017 14.2 0.7 0.027 13.6 0.7 1.2 1 0 0 1 1 1 0 RNAPII transcription regulator C-terminal DUF489 PF04356.12 ORY09609.1 - 0.54 10.2 9.9 0.056 13.4 5.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF489) Leucyl-specific PF14795.6 ORY09609.1 - 1.9 8.6 5.0 0.79 9.8 0.1 2.4 2 0 0 2 2 2 0 Leucine-tRNA synthetase-specific domain AA_permease_2 PF13520.6 ORY09610.1 - 1.8e-85 287.3 24.9 2.3e-85 287.0 24.9 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ORY09610.1 - 7.9e-13 47.8 26.1 1.1e-12 47.3 26.1 1.1 1 0 0 1 1 1 1 Amino acid permease Aa_trans PF01490.18 ORY09610.1 - 2.3e-05 23.3 13.0 4.4e-05 22.4 13.0 1.4 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein MASE3 PF17159.4 ORY09610.1 - 0.026 14.1 0.1 0.026 14.1 0.1 3.0 3 1 0 3 3 3 0 Membrane-associated sensor domain Orf78 PF06024.12 ORY09610.1 - 0.056 13.7 1.0 1.3 9.4 0.2 3.0 3 0 0 3 3 3 0 Orf78 (ac78) DUF2206 PF09971.9 ORY09610.1 - 0.081 11.7 0.9 0.49 9.1 0.0 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2206) Zn_clus PF00172.18 ORY09611.1 - 7e-10 38.9 8.1 1e-09 38.3 8.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ORY09611.1 - 0.00057 19.0 0.8 0.002 17.2 0.1 2.1 2 1 0 2 2 2 1 Fungal specific transcription factor domain ParB_C PF18064.1 ORY09611.1 - 0.0058 16.8 0.3 0.021 15.0 0.1 2.0 2 0 0 2 2 2 1 Centromere-binding protein ParB C-terminal Sugar_tr PF00083.24 ORY09612.1 - 1.7e-76 257.9 19.7 2e-76 257.7 19.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY09612.1 - 2.8e-28 98.9 44.9 3.5e-23 82.1 14.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ThiF PF00899.21 ORY09613.1 - 6e-109 363.1 0.0 3.9e-75 252.4 0.0 3.1 3 1 0 3 3 3 2 ThiF family ParA PF10609.9 ORY09613.1 - 4.6e-93 311.2 0.0 7.2e-93 310.6 0.0 1.3 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase UBA_e1_thiolCys PF10585.9 ORY09613.1 - 7.8e-91 304.5 0.2 1.2e-90 303.9 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_UFD PF09358.10 ORY09613.1 - 2.2e-32 111.6 0.1 4.2e-32 110.7 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin fold domain E1_FCCH PF16190.5 ORY09613.1 - 1.4e-31 108.5 0.1 2.6e-31 107.6 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_4HB PF16191.5 ORY09613.1 - 3.5e-26 91.2 0.2 1.4e-25 89.3 0.2 2.1 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle CbiA PF01656.23 ORY09613.1 - 1.2e-06 28.6 0.0 1.6e-05 25.0 0.0 2.7 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 ORY09613.1 - 0.00018 21.5 0.0 0.0015 18.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.15 ORY09613.1 - 0.0004 19.7 0.4 0.0012 18.2 0.3 1.8 1 1 1 2 2 2 1 Anion-transporting ATPase AAA_26 PF13500.6 ORY09613.1 - 0.027 14.3 0.0 0.27 11.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 ORY09613.1 - 0.19 11.6 0.1 0.43 10.5 0.1 1.5 1 0 0 1 1 1 0 RsgA GTPase DUF4834 PF16118.5 ORY09614.1 - 0.031 15.2 0.0 0.96 10.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) LapA_dom PF06305.11 ORY09614.1 - 0.48 10.3 1.9 12 5.8 0.0 2.6 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain DUF4690 PF15756.5 ORY09614.1 - 0.55 10.9 5.8 0.073 13.7 1.1 2.0 2 0 0 2 2 2 0 Small Novel Rich in Cartilage Syndecan PF01034.20 ORY09614.1 - 6.9 6.7 5.1 18 5.3 5.1 1.7 1 0 0 1 1 1 0 Syndecan domain GMC_oxred_N PF00732.19 ORY09615.1 - 2.2e-52 178.3 0.0 2.9e-52 177.9 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 ORY09615.1 - 1.6e-33 116.2 0.0 2.6e-33 115.6 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 ORY09615.1 - 2.2e-06 27.5 0.1 7.4e-05 22.5 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 ORY09615.1 - 9.4e-05 21.6 0.0 0.00015 21.0 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 ORY09615.1 - 0.00029 20.0 0.1 0.0011 18.1 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 ORY09615.1 - 0.00087 18.6 0.1 0.0044 16.3 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 ORY09615.1 - 0.011 14.8 0.4 0.34 9.9 0.1 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_8 PF13450.6 ORY09615.1 - 0.016 15.4 0.0 0.037 14.3 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 ORY09615.1 - 0.13 11.5 0.1 3.6 6.8 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 ORY09615.1 - 0.19 10.5 0.0 0.27 10.0 0.0 1.1 1 0 0 1 1 1 0 Tryptophan halogenase DUF2975 PF11188.8 ORY09616.1 - 0.58 10.0 6.5 0.043 13.7 0.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2975) PhyH PF05721.13 ORY09617.1 - 1.7e-14 54.6 0.0 2.3e-14 54.2 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Glutaredoxin PF00462.24 ORY09619.1 - 6.2e-12 45.6 0.0 1.4e-11 44.4 0.0 1.7 1 0 0 1 1 1 1 Glutaredoxin TraF PF13728.6 ORY09619.1 - 0.031 14.1 0.3 0.16 11.8 0.0 1.9 2 0 0 2 2 2 0 F plasmid transfer operon protein NARP1 PF12569.8 ORY09620.1 - 2.2 7.1 10.8 3 6.7 10.8 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF5401 PF17380.2 ORY09620.1 - 9.1 4.2 23.9 12 3.8 23.9 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5401) Clr5 PF14420.6 ORY09621.1 - 8.2e-15 54.8 2.3 1.9e-14 53.6 2.3 1.7 1 0 0 1 1 1 1 Clr5 domain Kelch_2 PF07646.15 ORY09622.1 - 0.048 13.6 0.0 1.1 9.4 0.0 2.5 2 0 0 2 2 2 0 Kelch motif YrhK PF14145.6 ORY09622.1 - 0.29 11.0 19.7 3.1 7.8 0.1 5.1 3 1 1 4 4 4 0 YrhK-like protein Neurensin PF14927.6 ORY09622.1 - 0.76 9.5 2.7 16 5.2 0.2 3.0 2 1 1 3 3 3 0 Neurensin MMS1_N PF10433.9 ORY09632.1 - 2e-130 435.7 0.0 3e-130 435.1 0.0 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 ORY09632.1 - 1e-77 261.6 0.0 3.1e-76 256.8 0.0 2.6 3 0 0 3 3 3 1 CPSF A subunit region HPS3_N PF14761.6 ORY09632.1 - 0.2 11.2 0.1 5.1 6.6 0.0 2.7 3 0 0 3 3 3 0 Hermansky-Pudlak syndrome 3 Sin_N PF04801.13 ORY09633.1 - 3.5e-28 99.0 3.2 3.8e-16 59.3 1.8 2.0 2 0 0 2 2 2 2 Sin-like protein conserved region Peptidase_S15 PF02129.18 ORY09633.1 - 0.054 13.1 2.1 0.19 11.3 1.9 1.9 1 1 1 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Ribosomal_60s PF00428.19 ORY09633.1 - 0.96 10.1 9.8 0.15 12.7 4.4 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein NAD_binding_2 PF03446.15 ORY09634.1 - 4.4e-37 127.7 0.0 7.3e-37 127.0 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 ORY09634.1 - 6.9e-25 87.7 0.0 1e-24 87.1 0.0 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 ORY09634.1 - 0.00022 21.8 0.0 0.00067 20.2 0.0 1.8 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent OCD_Mu_crystall PF02423.15 ORY09634.1 - 0.028 13.4 0.0 0.043 12.7 0.0 1.2 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family 2-Hacid_dh_C PF02826.19 ORY09634.1 - 0.05 13.0 0.0 0.083 12.2 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pmp3 PF01679.17 ORY09635.1 - 4e-18 65.3 7.8 6.2e-18 64.7 7.8 1.3 1 0 0 1 1 1 1 Proteolipid membrane potential modulator TMEM154 PF15102.6 ORY09636.1 - 0.0047 16.8 0.1 0.0071 16.3 0.1 1.3 1 0 0 1 1 1 1 TMEM154 protein family stn_TNFRSF12A PF12191.8 ORY09636.1 - 0.068 13.4 0.1 0.16 12.2 0.0 1.6 1 1 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Asp5 PF17000.5 ORY09637.1 - 0.0077 16.3 4.1 0.016 15.3 4.1 1.6 1 0 0 1 1 1 1 Accessory secretory protein Sec, Asp5 zf-C2H2 PF00096.26 ORY09638.1 - 0.014 15.8 1.7 0.014 15.8 1.7 3.3 2 1 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY09638.1 - 0.015 16.1 1.4 0.015 16.1 1.4 3.7 4 0 0 4 4 4 0 C2H2-type zinc finger zf-Di19 PF05605.12 ORY09638.1 - 0.14 12.5 5.6 0.2 12.0 4.0 2.2 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-ribbon_3 PF13248.6 ORY09638.1 - 0.22 11.0 4.0 1 8.8 0.1 2.8 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_6 PF13912.6 ORY09638.1 - 0.25 11.4 2.5 0.59 10.2 0.2 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 ORY09638.1 - 4.4 8.0 7.2 0.73 10.5 0.4 2.9 3 1 1 4 4 4 0 Zinc finger C2H2-type, 3 repeats Tti2 PF10521.9 ORY09639.1 - 2.3e-59 201.2 1.8 3.7e-59 200.6 1.8 1.3 1 0 0 1 1 1 1 Tti2 family PolyA_pol PF01743.20 ORY09639.1 - 1.6e-21 77.0 0.5 2.5e-20 73.2 0.5 2.4 1 1 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 ORY09639.1 - 3.2e-05 23.6 0.0 8.6e-05 22.2 0.0 1.7 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A tRNA_NucTran2_2 PF13735.6 ORY09639.1 - 0.00059 19.8 0.0 0.0011 18.9 0.0 1.4 1 0 0 1 1 1 1 tRNA nucleotidyltransferase domain 2 putative TRAPPC-Trs85 PF12739.7 ORY09640.1 - 1.1e-112 377.0 0.0 7.1e-112 374.3 0.0 1.9 2 0 0 2 2 2 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit OTU PF02338.19 ORY09641.1 - 3.9e-13 50.0 0.0 1.2e-12 48.4 0.0 1.8 1 1 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 ORY09641.1 - 0.0046 16.4 0.0 2 7.8 0.0 2.3 2 0 0 2 2 2 2 Peptidase C65 Otubain MoCF_biosynth PF00994.24 ORY09642.1 - 6e-53 178.4 0.0 1.9e-28 98.9 0.0 2.3 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.17 ORY09642.1 - 8.7e-42 142.5 2.5 8.7e-42 142.5 2.5 1.7 2 0 0 2 2 2 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.15 ORY09642.1 - 8.6e-16 57.9 0.6 2.1e-15 56.7 0.0 2.1 2 0 0 2 2 2 1 MoeA C-terminal region (domain IV) ATP-synt_C PF00137.21 ORY09643.1 - 3.5e-27 94.5 25.5 1.6e-15 57.1 10.3 2.4 2 0 0 2 2 2 2 ATP synthase subunit C SLATT_5 PF18160.1 ORY09643.1 - 0.089 12.1 1.7 0.54 9.5 0.0 2.1 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 Oxidored_q2 PF00420.24 ORY09643.1 - 3.1 7.5 10.3 0.11 12.2 1.0 2.9 3 1 0 3 3 3 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L TFIIA_gamma_C PF02751.14 ORY09644.1 - 9.6e-25 86.5 3.9 9.6e-25 86.5 3.9 1.6 2 0 0 2 2 2 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.16 ORY09644.1 - 3e-24 84.7 0.3 4.2e-24 84.3 0.3 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain EamA PF00892.20 ORY09645.1 - 0.0011 19.1 20.5 0.0049 17.0 20.5 1.8 1 1 0 1 1 1 1 EamA-like transporter family PAM2 PF07145.15 ORY09647.1 - 2.4e-05 23.7 13.7 0.00039 19.9 0.4 3.7 3 0 0 3 3 3 2 Ataxin-2 C-terminal region Lipase_GDSL_2 PF13472.6 ORY09648.1 - 1.9e-13 51.2 0.0 2.4e-13 50.9 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 ORY09648.1 - 1.5e-09 38.1 0.0 1.6e-09 38.0 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 ORY09648.1 - 2.7e-06 27.6 0.0 4.1e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family OSK PF17182.4 ORY09648.1 - 0.0046 16.2 0.0 0.0065 15.7 0.0 1.2 1 0 0 1 1 1 1 OSK domain Stealth_CR2 PF11380.8 ORY09648.1 - 0.11 12.6 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 Stealth protein CR2, conserved region 2 Herpes_gE PF02480.16 ORY09649.1 - 9.6e-06 24.6 0.7 0.023 13.5 0.1 2.0 2 0 0 2 2 2 2 Alphaherpesvirus glycoprotein E Adeno_E3_CR2 PF02439.15 ORY09649.1 - 0.005 16.6 5.1 0.68 9.7 0.3 2.4 2 0 0 2 2 2 2 Adenovirus E3 region protein CR2 EphA2_TM PF14575.6 ORY09649.1 - 0.0068 17.3 0.1 4.2 8.3 0.1 2.3 2 0 0 2 2 2 2 Ephrin type-A receptor 2 transmembrane domain DUF3040 PF11239.8 ORY09649.1 - 0.0084 16.4 0.0 6 7.2 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF3040) PRIMA1 PF16101.5 ORY09649.1 - 0.011 15.7 0.5 0.062 13.3 0.0 2.0 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 DUF4381 PF14316.6 ORY09649.1 - 0.02 15.2 0.3 3.1 8.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) LapA_dom PF06305.11 ORY09649.1 - 0.034 14.0 1.0 0.26 11.1 0.1 2.2 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Rhabdo_glycop PF00974.18 ORY09649.1 - 0.22 9.9 1.0 1.3 7.4 1.0 1.9 1 1 0 1 1 1 0 Rhabdovirus spike glycoprotein MRI PF15325.6 ORY09649.1 - 0.44 11.6 0.2 0.44 11.6 0.2 2.2 2 0 0 2 2 2 0 Modulator of retrovirus infection DUF202 PF02656.15 ORY09649.1 - 2.2 8.8 7.2 40 4.7 0.4 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF202) CcmD PF04995.14 ORY09649.1 - 6.4 6.9 8.0 1.1 9.4 1.0 2.4 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) CAF1A PF12253.8 ORY09650.1 - 0.0077 16.4 1.0 0.032 14.4 1.0 2.1 1 0 0 1 1 1 1 Chromatin assembly factor 1 subunit A PEX11 PF05648.14 ORY09651.1 - 0.026 14.0 0.1 0.37 10.2 0.0 2.2 2 0 0 2 2 2 0 Peroxisomal biogenesis factor 11 (PEX11) PBC PF03792.13 ORY09651.1 - 0.045 13.5 0.0 0.089 12.5 0.0 1.4 1 0 0 1 1 1 0 PBC domain DUF5327 PF17261.2 ORY09651.1 - 0.092 13.5 4.3 2 9.2 0.3 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF5327) Pyridox_oxase_2 PF12766.7 ORY09652.1 - 6.2e-27 94.1 0.0 1.1e-26 93.3 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase RNA_pol_Rpb1_1 PF04997.12 ORY09653.1 - 0.1 11.9 0.1 0.13 11.5 0.1 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 1 CDC27 PF09507.10 ORY09654.1 - 1.1e-89 301.8 26.4 1.3e-89 301.6 26.4 1.1 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 Ribosomal_S25 PF03297.15 ORY09654.1 - 0.011 16.0 0.1 0.011 16.0 0.1 3.7 3 1 2 5 5 5 0 S25 ribosomal protein TerB_C PF15615.6 ORY09654.1 - 8.6 6.6 14.6 1.5 9.1 4.2 3.3 3 0 0 3 3 3 0 TerB-C domain TFCD_C PF12612.8 ORY09655.1 - 5.4e-24 85.1 7.6 4.9e-23 82.0 4.8 3.3 2 1 0 2 2 2 1 Tubulin folding cofactor D C terminal HEAT PF02985.22 ORY09655.1 - 0.00058 19.9 9.1 4.7 7.7 0.0 7.7 8 0 0 8 8 8 2 HEAT repeat HEAT_2 PF13646.6 ORY09655.1 - 0.0018 18.6 1.8 1.1 9.6 0.0 4.3 5 0 0 5 5 5 1 HEAT repeats IFRD PF05004.13 ORY09655.1 - 0.01 15.0 4.1 0.1 11.7 0.4 3.4 3 0 0 3 3 3 0 Interferon-related developmental regulator (IFRD) HEAT_EZ PF13513.6 ORY09655.1 - 0.067 13.7 1.2 13 6.4 0.0 5.3 6 0 0 6 6 6 0 HEAT-like repeat ETC_C1_NDUFA4 PF04800.12 ORY09656.1 - 6.1e-35 119.3 1.5 8.8e-35 118.8 1.5 1.2 1 0 0 1 1 1 1 ETC complex I subunit conserved region F1F0-ATPsyn_F PF10791.9 ORY09657.1 - 8.2e-39 132.0 0.4 9.3e-39 131.8 0.4 1.0 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi WRW PF10206.9 ORY09657.1 - 0.03 14.7 0.1 0.034 14.5 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial F1F0-ATP synthase, subunit f TauD PF02668.16 ORY09660.1 - 1.3e-20 74.3 0.0 1.6e-20 74.0 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF520 PF04461.13 ORY09660.1 - 0.073 13.2 0.1 0.11 12.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF520) Zn_clus PF00172.18 ORY09661.1 - 0.0049 17.0 7.3 0.013 15.6 7.3 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3176 PF11374.8 ORY09663.1 - 1.6e-28 99.0 1.5 3.6e-28 97.9 0.9 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF3176) HET PF06985.11 ORY09664.1 - 8.9e-34 116.9 0.8 2.1e-33 115.7 0.8 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ANTH PF07651.16 ORY09664.1 - 0.045 12.7 0.0 0.088 11.8 0.0 1.4 1 0 0 1 1 1 0 ANTH domain Arb1 PF09692.10 ORY09666.1 - 1.7e-121 406.2 0.0 2.2e-121 405.8 0.0 1.1 1 0 0 1 1 1 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 La PF05383.17 ORY09666.1 - 4.2e-17 62.0 0.1 1.1e-16 60.6 0.0 1.8 2 0 0 2 2 2 1 La domain IPK PF03770.16 ORY09667.1 - 1.3e-54 185.0 0.0 1.6e-54 184.8 0.0 1.1 1 0 0 1 1 1 1 Inositol polyphosphate kinase CLP1_P PF16575.5 ORY09668.1 - 3.4e-36 124.8 0.0 7.3e-36 123.7 0.0 1.5 1 1 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop CLP1_N PF16573.5 ORY09668.1 - 7.4e-32 109.4 0.0 1.2e-31 108.8 0.0 1.3 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor Clp1 PF06807.14 ORY09668.1 - 7.6e-28 97.3 0.0 1.3e-27 96.5 0.0 1.4 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 ATP_bind_1 PF03029.17 ORY09668.1 - 2.9e-05 24.0 0.0 0.00015 21.6 0.0 1.9 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 ORY09668.1 - 0.00037 20.6 0.0 0.0043 17.1 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 ORY09668.1 - 0.029 14.8 0.0 0.054 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_35 PF14516.6 ORY09668.1 - 0.065 12.1 0.0 0.096 11.5 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain Dynamin_N PF00350.23 ORY09668.1 - 0.08 13.0 0.0 11 6.1 0.0 2.3 2 0 0 2 2 2 0 Dynamin family zf-C2H2 PF00096.26 ORY09669.1 - 3.2e-16 58.8 44.6 0.00097 19.5 0.2 7.5 8 0 0 8 8 7 6 Zinc finger, C2H2 type zf-met PF12874.7 ORY09669.1 - 3.2e-15 56.0 16.0 0.0042 17.4 0.1 6.9 7 0 0 7 7 6 5 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 ORY09669.1 - 2.5e-14 52.7 33.2 0.077 13.9 0.1 8.4 8 0 0 8 8 8 6 C2H2-type zinc finger zf-C2H2_2 PF12756.7 ORY09669.1 - 7.5e-10 39.1 14.7 0.53 10.6 0.1 6.7 3 2 4 7 7 7 4 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 ORY09669.1 - 2.2e-08 34.2 8.4 0.34 11.2 0.1 6.3 6 0 0 6 6 6 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 ORY09669.1 - 1.6e-05 24.8 18.5 0.69 10.0 0.7 6.5 6 0 0 6 6 6 3 C2H2-type zinc finger zf-C2H2_11 PF16622.5 ORY09669.1 - 7.2e-05 22.5 28.2 0.17 11.7 0.0 6.6 7 0 0 7 7 7 3 zinc-finger C2H2-type CpXC PF14353.6 ORY09669.1 - 0.00016 21.7 4.8 0.18 11.9 0.8 3.9 2 1 2 4 4 4 2 CpXC protein GASA PF02704.14 ORY09669.1 - 0.052 13.7 0.6 0.052 13.7 0.6 2.4 2 0 0 2 2 1 0 Gibberellin regulated protein DUF2256 PF10013.9 ORY09669.1 - 0.057 13.5 24.9 0.2 11.8 0.0 6.2 7 0 0 7 7 6 0 Uncharacterized protein conserved in bacteria (DUF2256) DUF629 PF04780.12 ORY09669.1 - 0.1 11.1 0.4 15 4.0 0.1 2.8 3 1 0 3 3 3 0 Protein of unknown function (DUF629) zf-C2H2_8 PF15909.5 ORY09669.1 - 0.44 10.9 9.1 0.27 11.6 1.4 3.7 3 2 0 3 3 3 0 C2H2-type zinc ribbon zf_UBZ PF18439.1 ORY09669.1 - 1.1 8.9 13.6 52 3.5 0.0 5.7 6 0 0 6 6 6 0 Ubiquitin-Binding Zinc Finger zf-C2HC_2 PF13913.6 ORY09669.1 - 1.3 9.0 0.0 1.3 9.0 0.0 5.5 6 0 0 6 6 6 0 zinc-finger of a C2HC-type TAXi_N PF14543.6 ORY09669.1 - 5 7.3 8.0 1 9.6 0.3 2.4 2 0 0 2 2 2 0 Xylanase inhibitor N-terminal Yippee-Mis18 PF03226.14 ORY09669.1 - 6.6 7.0 6.9 9.4 6.5 0.0 4.3 5 1 0 5 5 5 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-C2H2_3rep PF18868.1 ORY09669.1 - 8.3 7.1 7.3 67 4.2 0.0 4.5 4 2 0 4 4 4 0 Zinc finger C2H2-type, 3 repeats DUF775 PF05603.12 ORY09670.1 - 2.6e-66 222.9 0.0 3e-66 222.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF775) BBE PF08031.12 ORY09671.1 - 6.3e-05 23.0 0.0 9.5e-05 22.4 0.0 1.4 1 1 0 1 1 1 1 Berberine and berberine like Cupin_8 PF13621.6 ORY09672.1 - 1.8e-35 122.9 0.0 2.8e-35 122.2 0.0 1.3 1 0 0 1 1 1 1 Cupin-like domain LCM PF04072.14 ORY09672.1 - 6e-22 78.5 0.0 9.4e-22 77.9 0.0 1.2 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Kelch_4 PF13418.6 ORY09672.1 - 5.9e-18 64.6 3.4 0.0002 21.3 0.0 6.0 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.6 ORY09672.1 - 1.1e-10 41.2 0.1 0.015 15.3 0.0 5.4 5 0 0 5 5 5 2 Kelch motif Cupin_4 PF08007.12 ORY09672.1 - 2.1e-06 27.4 0.0 3.9e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Cupin superfamily protein Kelch_3 PF13415.6 ORY09672.1 - 0.0014 18.9 0.1 0.012 15.9 0.0 2.7 2 0 0 2 2 2 1 Galactose oxidase, central domain ANAPC4_WD40 PF12894.7 ORY09673.1 - 0.00039 20.7 0.0 0.81 10.0 0.0 4.2 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 ORY09673.1 - 0.0018 19.1 0.0 0.17 12.8 0.0 3.5 4 0 0 4 4 4 1 WD domain, G-beta repeat BBS2_N PF14781.6 ORY09673.1 - 0.064 13.2 0.5 3.4 7.6 0.0 3.2 4 1 0 4 4 4 0 Ciliary BBSome complex subunit 2, N-terminal Hira PF07569.11 ORY09673.1 - 0.066 12.9 0.0 1.9 8.1 0.0 2.5 2 0 0 2 2 2 0 TUP1-like enhancer of split PI31_Prot_N PF11566.8 ORY09674.1 - 2.8e-54 183.3 0.0 3.4e-54 183.0 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.11 ORY09674.1 - 9.5e-18 65.2 16.7 9.5e-18 65.2 16.7 3.4 2 2 1 3 3 3 1 PI31 proteasome regulator zf-C2H2 PF00096.26 ORY09677.1 - 1.2e-07 31.7 20.1 0.00079 19.8 2.5 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY09677.1 - 0.00038 21.0 22.0 0.013 16.3 2.0 3.9 4 0 0 4 4 4 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORY09677.1 - 0.0071 16.7 11.2 0.011 16.1 0.5 3.5 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.8 ORY09677.1 - 0.056 13.8 4.7 3 8.2 1.1 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ORY09677.1 - 2.4 8.7 11.4 16 6.0 2.0 3.8 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 ORY09677.1 - 8.5 6.5 18.1 0.26 11.3 1.1 3.8 4 0 0 4 4 4 0 C2H2-type zinc finger Ion_trans PF00520.31 ORY09678.1 - 6.8e-05 22.2 17.6 0.00014 21.2 17.6 1.5 1 1 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 ORY09678.1 - 0.012 14.3 7.9 0.35 9.5 0.1 2.1 1 1 1 2 2 2 0 Polycystin cation channel DUF3112 PF11309.8 ORY09680.1 - 4.9e-13 49.1 3.6 1.3e-09 37.9 0.4 3.1 3 1 1 4 4 4 2 Protein of unknown function (DUF3112) Sulf_transp PF04143.14 ORY09680.1 - 0.13 11.8 6.1 0.25 10.8 6.1 1.6 1 1 0 1 1 1 0 Sulphur transport DSPc PF00782.20 ORY09681.1 - 6.4e-29 100.5 0.0 1.9e-21 76.3 0.0 2.3 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 ORY09681.1 - 0.00016 21.4 0.0 0.003 17.2 0.0 2.2 2 0 0 2 2 2 1 Protein-tyrosine phosphatase DNA_pol_delta_4 PF04081.13 ORY09682.1 - 2.4e-39 134.7 1.0 3.3e-39 134.2 0.8 1.3 1 1 0 1 1 1 1 DNA polymerase delta, subunit 4 AroM PF07302.11 ORY09682.1 - 0.056 12.8 0.1 0.08 12.3 0.1 1.2 1 0 0 1 1 1 0 AroM protein DcpS PF05652.12 ORY09683.1 - 2.9e-36 124.5 0.0 4.5e-36 123.9 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal DcpS_C PF11969.8 ORY09683.1 - 7.8e-29 100.5 0.1 1.2e-28 99.9 0.1 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Git3 PF11710.8 ORY09684.1 - 1.5e-39 135.9 6.1 1.5e-39 135.9 6.1 1.6 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 GPR_Gpa2_C PF11970.8 ORY09684.1 - 8.8e-27 93.0 3.1 2.2e-26 91.7 3.1 1.7 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term Peptidase_C12 PF01088.21 ORY09685.1 - 2.5e-55 187.5 0.0 3.2e-55 187.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 tRNA_bind PF01588.20 ORY09686.1 - 4e-21 74.9 0.0 1.1e-20 73.6 0.0 1.8 1 1 0 1 1 1 1 Putative tRNA binding domain GST_C_2 PF13410.6 ORY09686.1 - 0.00027 20.9 0.0 0.00067 19.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 ORY09686.1 - 0.013 15.7 0.8 0.052 13.8 0.0 2.3 3 0 0 3 3 3 0 Glutathione S-transferase, C-terminal domain CHASE8 PF17152.4 ORY09686.1 - 0.042 14.1 0.1 0.23 11.7 0.1 2.2 1 1 0 1 1 1 0 Periplasmic sensor domain SPATA25 PF15218.6 ORY09686.1 - 0.11 12.2 2.1 1.9 8.2 0.1 2.3 2 0 0 2 2 2 0 Spermatogenesis-associated protein 25 Epimerase PF01370.21 ORY09687.1 - 9.6e-48 162.7 0.0 1.3e-47 162.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ORY09687.1 - 1.4e-46 159.4 0.0 2e-46 158.9 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 ORY09687.1 - 5.2e-16 58.5 0.0 9.4e-15 54.3 0.0 2.0 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 ORY09687.1 - 4e-13 49.2 0.0 3.5e-11 42.8 0.0 2.2 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 ORY09687.1 - 1.7e-11 43.8 0.0 2.3e-11 43.3 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 ORY09687.1 - 4.8e-11 42.5 0.0 7.6e-11 41.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.12 ORY09687.1 - 1.8e-05 24.1 0.0 0.0017 17.6 0.0 2.3 1 1 0 1 1 1 1 Male sterility protein KR PF08659.10 ORY09687.1 - 2.4e-05 24.3 0.0 4.4e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 ORY09687.1 - 0.00013 21.6 0.0 0.00021 20.9 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NmrA PF05368.13 ORY09687.1 - 0.023 14.3 0.0 0.073 12.6 0.0 1.8 2 0 0 2 2 2 0 NmrA-like family UDPG_MGDP_dh_N PF03721.14 ORY09687.1 - 0.06 12.9 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Sad1_UNC PF07738.13 ORY09688.1 - 3.5e-18 65.9 0.0 6.3e-18 65.1 0.0 1.4 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal adh_short PF00106.25 ORY09689.1 - 1.1e-17 64.1 0.1 8.9e-16 57.9 0.2 2.1 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 ORY09689.1 - 6.2e-10 39.3 0.3 9.2e-10 38.7 0.3 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 ORY09689.1 - 6.7e-09 35.6 0.3 6.2e-07 29.2 0.2 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Zn_clus PF00172.18 ORY09690.1 - 8.5e-07 29.0 11.9 2e-06 27.8 11.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Proteasom_Rpn13 PF04683.13 ORY09691.1 - 2.8e-24 85.5 0.0 4.3e-24 84.9 0.0 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor RPN13_C PF16550.5 ORY09691.1 - 4.9e-12 46.0 0.7 1.8e-10 41.0 0.7 2.3 1 1 0 1 1 1 1 UCH-binding domain MOR2-PAG1_C PF14225.6 ORY09691.1 - 0.038 13.8 0.1 0.056 13.3 0.1 1.1 1 0 0 1 1 1 0 Cell morphogenesis C-terminal Ribosomal_L6e PF01159.19 ORY09692.1 - 7.6e-39 132.7 1.1 1.2e-38 132.0 1.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L6e GNAT_acetyltr_2 PF13718.6 ORY09692.1 - 0.014 14.8 0.2 0.023 14.1 0.2 1.3 1 0 0 1 1 1 0 GNAT acetyltransferase 2 FA_hydroxylase PF04116.13 ORY09693.1 - 6.3e-16 58.9 7.0 6.3e-16 58.9 7.0 1.8 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Abhydrolase_6 PF12697.7 ORY09694.1 - 2.2e-08 35.0 1.1 1.3e-07 32.5 0.6 2.6 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ORY09694.1 - 2e-06 27.6 0.0 5.3e-06 26.3 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ORY09694.1 - 0.0023 17.3 0.1 0.022 14.0 0.0 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DUF5340 PF17275.2 ORY09694.1 - 0.023 14.8 0.2 0.16 12.1 0.0 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5340) RTA1 PF04479.13 ORY09695.1 - 1.9e-39 135.4 3.0 4e-39 134.4 3.0 1.5 1 1 0 1 1 1 1 RTA1 like protein TMEM239 PF15841.5 ORY09696.1 - 0.022 14.7 0.2 0.034 14.1 0.2 1.2 1 0 0 1 1 1 0 Transmembrane protein 239 family Thioesterase PF00975.20 ORY09722.1 - 1e-06 29.1 0.0 0.0033 17.6 0.0 2.1 2 0 0 2 2 2 2 Thioesterase domain Prefoldin PF02996.17 ORY09723.1 - 4.1e-33 113.8 0.5 6.7e-33 113.2 0.1 1.5 2 0 0 2 2 2 1 Prefoldin subunit PspA_IM30 PF04012.12 ORY09723.1 - 0.013 15.1 0.9 0.94 9.0 0.1 2.2 2 0 0 2 2 2 0 PspA/IM30 family Filament PF00038.21 ORY09723.1 - 0.017 14.7 1.6 2 7.9 0.1 2.0 2 0 0 2 2 2 0 Intermediate filament protein LMP PF04778.12 ORY09723.1 - 0.017 15.0 0.6 1.7 8.6 0.0 2.2 2 0 0 2 2 2 0 LMP repeated region APG17 PF04108.12 ORY09723.1 - 0.017 14.2 0.6 0.041 13.0 0.1 1.7 2 0 0 2 2 2 0 Autophagy protein Apg17 Prefoldin_2 PF01920.20 ORY09723.1 - 0.026 14.5 1.2 0.18 11.8 0.1 2.3 2 1 0 2 2 2 0 Prefoldin subunit DUF1664 PF07889.12 ORY09723.1 - 0.038 14.0 0.5 9.8 6.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Lebercilin PF15619.6 ORY09723.1 - 0.043 13.5 0.8 0.44 10.2 0.1 2.0 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DASH_Spc34 PF08657.10 ORY09723.1 - 0.043 13.6 0.1 0.52 10.1 0.1 2.0 2 0 0 2 2 2 0 DASH complex subunit Spc34 CLZ PF16526.5 ORY09723.1 - 0.11 12.8 0.7 2 8.8 0.1 2.4 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Glyco_hydro_47 PF01532.20 ORY09726.1 - 2.4e-194 646.5 0.1 2.8e-194 646.3 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Cpn60_TCP1 PF00118.24 ORY09727.1 - 5.2e-164 546.5 0.1 5.8e-164 546.3 0.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Herpes_UL6 PF01763.16 ORY09727.1 - 0.027 13.0 0.0 0.038 12.5 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like Nop PF01798.18 ORY09728.1 - 1.9e-86 289.3 0.1 1.9e-86 289.3 0.1 1.9 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 ORY09728.1 - 1.7e-16 60.4 0.0 1.7e-16 60.4 0.0 2.5 3 0 0 3 3 3 1 NOP5NT (NUC127) domain DUF3408 PF11888.8 ORY09728.1 - 0.95 9.6 10.1 55 3.9 9.9 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) HUN PF08729.10 ORY09729.1 - 7.3e-08 32.3 0.3 1.7e-07 31.1 0.3 1.5 1 0 0 1 1 1 1 HPC2 and ubinuclein domain DUF2370 PF10176.9 ORY09732.1 - 3.2e-90 301.7 0.0 5.4e-90 301.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) DIOX_N PF14226.6 ORY09734.1 - 5.7e-29 101.3 0.0 9.1e-29 100.6 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 ORY09734.1 - 1.6e-13 51.0 0.0 3.6e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Xpo1 PF08389.12 ORY09735.1 - 1.9e-09 37.8 0.6 8.9e-07 29.1 0.0 3.4 3 0 0 3 3 3 2 Exportin 1-like protein IBN_N PF03810.19 ORY09735.1 - 1.1e-07 31.6 0.4 2.9e-05 23.9 0.0 3.8 2 1 1 3 3 3 1 Importin-beta N-terminal domain Clusterin PF01093.17 ORY09735.1 - 0.11 11.5 0.6 0.21 10.6 0.6 1.3 1 0 0 1 1 1 0 Clusterin Glyco_hydro_5_C PF18564.1 ORY09736.1 - 2.1e-20 73.0 0.0 8.9e-20 71.0 0.0 2.1 2 0 0 2 2 2 1 Glycoside hydrolase family 5 C-terminal domain Cellulase PF00150.18 ORY09736.1 - 2.5e-08 33.7 4.0 1.3e-06 28.1 1.6 2.8 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) DnaJ PF00226.31 ORY09737.1 - 1.8e-19 69.6 0.7 1.8e-19 69.6 0.7 2.4 2 0 0 2 2 2 1 DnaJ domain TPR_2 PF07719.17 ORY09737.1 - 3.8e-19 67.2 9.7 0.00028 20.8 0.0 8.1 9 0 0 9 9 7 4 Tetratricopeptide repeat TPR_1 PF00515.28 ORY09737.1 - 7.7e-19 66.7 5.0 8.9e-06 25.3 0.0 6.0 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 ORY09737.1 - 9.5e-12 44.2 1.8 0.01 16.0 0.0 6.2 7 0 0 7 7 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 ORY09737.1 - 2e-10 40.6 8.1 0.00071 19.7 0.0 5.2 2 1 3 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 ORY09737.1 - 3e-10 40.5 7.8 0.0015 19.0 0.0 4.8 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 ORY09737.1 - 3.8e-10 39.7 10.4 0.049 14.5 0.1 7.1 3 2 3 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 ORY09737.1 - 1.8e-07 31.7 12.4 0.00067 20.3 0.1 5.2 3 1 2 5 5 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 ORY09737.1 - 1.9e-05 25.0 12.6 2.5 8.9 0.0 7.9 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 ORY09737.1 - 3.6e-05 23.5 0.9 29 5.0 0.0 5.2 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.6 ORY09737.1 - 6.5e-05 23.0 0.5 0.047 14.1 0.0 5.1 5 1 1 6 6 5 1 Tetratricopeptide repeat PknG_TPR PF16918.5 ORY09737.1 - 0.0011 17.8 2.3 0.0042 15.9 0.5 2.4 3 0 0 3 3 3 1 Protein kinase G tetratricopeptide repeat TPR_12 PF13424.6 ORY09737.1 - 0.0022 18.2 13.8 0.12 12.7 0.2 6.3 5 3 1 6 6 6 1 Tetratricopeptide repeat TPR_11 PF13414.6 ORY09737.1 - 0.0024 17.5 0.0 6 6.6 0.0 5.0 5 1 1 6 6 6 1 TPR repeat IR1-M PF12185.8 ORY09737.1 - 0.0044 16.9 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 Nup358/RanBP2 E3 ligase domain ANAPC3 PF12895.7 ORY09737.1 - 0.066 13.5 12.8 3.2 8.0 0.0 4.8 5 1 0 5 5 4 0 Anaphase-promoting complex, cyclosome, subunit 3 Alkyl_sulf_dimr PF14863.6 ORY09737.1 - 0.11 13.0 4.0 2.3 8.7 0.4 3.2 3 0 0 3 3 3 0 Alkyl sulfatase dimerisation ArnB_C PF18677.1 ORY09737.1 - 0.22 11.6 2.7 0.36 11.0 0.8 2.5 2 1 0 2 2 2 0 Archaellum regulatory network B, C-terminal domain Fis1_TPR_C PF14853.6 ORY09737.1 - 0.95 9.6 5.5 6.3 7.0 0.1 4.3 4 1 1 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.6 ORY09737.1 - 2.4 8.2 4.5 22 5.1 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat YfdX PF10938.8 ORY09737.1 - 5 7.1 12.9 12 5.9 0.0 3.7 3 1 0 3 3 3 0 YfdX protein DUF2013 PF09431.10 ORY09738.1 - 4.8e-50 169.3 0.1 1.3e-49 167.9 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2013) Ribonuc_2-5A PF06479.12 ORY09738.1 - 0.015 15.5 0.0 0.048 13.8 0.0 1.8 2 0 0 2 2 2 0 Ribonuclease 2-5A NopRA1 PF16201.5 ORY09738.1 - 0.035 13.7 0.3 0.26 10.8 0.0 2.4 2 1 2 4 4 4 0 Nucleolar pre-ribosomal-associated protein 1 NACHT PF05729.12 ORY09742.1 - 1e-05 25.6 1.6 6.5e-05 22.9 0.1 2.8 2 1 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 ORY09742.1 - 4.7e-05 23.8 0.0 0.00022 21.7 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 ORY09742.1 - 0.015 15.9 0.1 0.65 10.5 0.0 3.1 4 0 0 4 4 4 0 AAA domain AAA_22 PF13401.6 ORY09742.1 - 0.022 15.0 0.0 0.13 12.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 ORY09742.1 - 0.19 11.8 0.0 0.7 10.0 0.0 1.9 1 0 0 1 1 1 0 50S ribosome-binding GTPase OTU PF02338.19 ORY09743.1 - 4.4e-06 27.2 0.0 7.6e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease Bromodomain PF00439.25 ORY09744.1 - 2.8e-41 139.5 7.0 1.6e-20 72.9 1.1 2.6 2 0 0 2 2 2 2 Bromodomain BAH PF01426.18 ORY09744.1 - 1.4e-17 63.7 0.8 1.4e-17 63.7 0.8 2.1 2 0 0 2 2 2 1 BAH domain NOA36 PF06524.12 ORY09744.1 - 0.12 11.7 8.3 0.28 10.5 8.3 1.7 1 0 0 1 1 1 0 NOA36 protein HTH_32 PF13565.6 ORY09744.1 - 0.13 12.9 0.4 2.6 8.7 0.2 3.1 2 0 0 2 2 2 0 Homeodomain-like domain CDC45 PF02724.14 ORY09744.1 - 0.3 9.3 18.8 0.01 14.2 10.9 2.0 2 0 0 2 2 2 0 CDC45-like protein GCIP PF13324.6 ORY09744.1 - 2.9 7.4 5.5 6.1 6.4 5.5 1.4 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Acyl-CoA_dh_1 PF00441.24 ORY09745.1 - 5.2e-35 120.9 0.4 8.6e-35 120.2 0.4 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.28 ORY09745.1 - 1.5e-19 69.9 0.0 4.1e-19 68.5 0.0 1.8 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.19 ORY09745.1 - 2.1e-17 63.1 0.1 4e-17 62.2 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 ORY09745.1 - 1.8e-10 41.5 0.1 4.6e-10 40.1 0.1 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 ORY09745.1 - 5.2e-08 33.2 0.0 1.1e-07 32.2 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain zf-AN1 PF01428.16 ORY09746.1 - 4.1e-12 46.0 4.7 4.1e-12 46.0 4.7 1.4 1 1 0 1 1 1 1 AN1-like Zinc finger ubiquitin PF00240.23 ORY09746.1 - 1.6e-10 40.6 0.0 3.8e-10 39.4 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin family Sde2_N_Ubi PF13019.6 ORY09746.1 - 0.0016 18.3 0.8 0.0028 17.5 0.8 1.4 1 0 0 1 1 1 1 Silencing defective 2 N-terminal ubiquitin domain DUF2407 PF10302.9 ORY09746.1 - 0.025 15.1 0.1 0.03 14.9 0.1 1.4 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain Rad60-SLD PF11976.8 ORY09746.1 - 0.046 13.6 0.0 0.086 12.7 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like MFS_1 PF07690.16 ORY09748.1 - 1e-24 87.1 43.0 1e-22 80.5 33.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ABC2_membrane_5 PF13346.6 ORY09748.1 - 0.0075 15.8 2.2 0.0075 15.8 2.2 3.6 3 2 1 4 4 4 1 ABC-2 family transporter protein Glyco_transf_34 PF05637.12 ORY09749.1 - 3e-28 99.2 1.0 2.5e-26 92.8 1.0 2.1 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Nucleotid_trans PF03407.16 ORY09749.1 - 0.00051 20.1 0.1 0.00077 19.5 0.1 1.3 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase DUF5317 PF17248.2 ORY09752.1 - 0.42 10.6 5.0 10 6.1 1.3 2.6 2 1 1 3 3 3 0 Family of unknown function (DUF5317) AA_permease_2 PF13520.6 ORY09754.1 - 1.6e-57 195.3 47.0 2.1e-57 194.9 47.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ORY09754.1 - 5.7e-24 84.6 39.8 7.9e-24 84.1 39.8 1.0 1 0 0 1 1 1 1 Amino acid permease Tweety PF04906.13 ORY09754.1 - 0.013 14.2 2.3 0.029 13.0 2.3 1.5 1 0 0 1 1 1 0 Tweety DUF3043 PF11241.8 ORY09754.1 - 5.3 7.0 14.4 0.64 10.0 0.4 3.5 2 1 0 3 3 3 0 Protein of unknown function (DUF3043) Peptidase_S41 PF03572.18 ORY09755.1 - 1.4e-08 34.5 0.0 2.9e-08 33.5 0.0 1.5 1 1 0 1 1 1 1 Peptidase family S41 2_5_RNA_ligase2 PF13563.6 ORY09756.1 - 3.4e-27 95.2 0.0 7.6e-27 94.1 0.0 1.6 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily MJ1316 PF04457.12 ORY09756.1 - 1.2e-19 70.7 0.6 3.2e-19 69.5 0.1 2.0 2 0 0 2 2 2 1 MJ1316 RNA cyclic group end recognition domain PAP_central PF04928.17 ORY09756.1 - 8.6e-18 64.2 0.0 1.7e-17 63.2 0.0 1.4 1 0 0 1 1 1 1 Poly(A) polymerase central domain Exo_endo_phos PF03372.23 ORY09756.1 - 5.6e-10 39.1 0.0 3e-09 36.8 0.0 2.2 2 1 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family NTP_transf_2 PF01909.23 ORY09756.1 - 7.9e-05 22.9 0.0 0.00021 21.5 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain Nrap_D2 PF17403.2 ORY09756.1 - 0.088 12.6 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Nrap protein PAP/OAS-like domain Acyl_transf_3 PF01757.22 ORY09758.1 - 0.17 10.9 37.1 0.42 9.6 37.1 1.7 1 1 0 1 1 1 0 Acyltransferase family Glyco_tranf_2_3 PF13641.6 ORY09759.1 - 3e-17 63.3 0.0 4.5e-17 62.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 ORY09759.1 - 2.3e-16 60.3 11.1 2.3e-16 60.3 11.1 2.5 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 ORY09759.1 - 4.4e-06 26.3 0.0 7.6e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 ORY09759.1 - 1.2e-05 25.1 0.0 1.8e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Phage_holin_2_3 PF16080.5 ORY09759.1 - 0.01 15.5 0.3 0.033 13.9 0.3 1.8 1 0 0 1 1 1 0 Bacteriophage holin family HP1 Glucos_trans_II PF14264.6 ORY09759.1 - 0.38 10.1 17.1 0.052 12.9 6.0 2.2 2 0 0 2 2 2 0 Glucosyl transferase GtrII Bee_toxin PF17454.2 ORY09759.1 - 7.5 6.7 6.9 1 9.5 0.8 2.5 2 0 0 2 2 2 0 Honey bee toxin Acyl_transf_3 PF01757.22 ORY09760.1 - 1.4e-05 24.4 38.3 1.4e-05 24.4 38.3 1.6 2 0 0 2 2 2 1 Acyltransferase family Glyco_hydro_16 PF00722.21 ORY09760.1 - 0.0055 16.2 0.6 0.016 14.7 0.0 2.1 3 1 0 3 3 3 1 Glycosyl hydrolases family 16 Ank_2 PF12796.7 ORY09761.1 - 3.6e-13 49.9 0.0 6.1e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY09761.1 - 4.2e-12 46.3 0.1 1.2e-07 32.1 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY09761.1 - 1.6e-10 40.3 0.3 0.038 14.5 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat ZZ PF00569.17 ORY09761.1 - 3.2e-08 33.3 10.6 7.6e-08 32.0 10.6 1.7 1 0 0 1 1 1 1 Zinc finger, ZZ type Ank_5 PF13857.6 ORY09761.1 - 5e-08 33.1 1.8 4.7e-05 23.6 0.2 3.2 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 ORY09761.1 - 3.3e-06 27.3 0.1 0.025 15.0 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat C1_2 PF03107.16 ORY09761.1 - 0.035 14.4 11.4 0.097 13.0 11.4 1.8 1 0 0 1 1 1 0 C1 domain Ank_2 PF12796.7 ORY09762.1 - 5.7e-11 42.9 0.2 2.9e-10 40.6 0.2 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ORY09762.1 - 4.1e-08 32.9 0.1 0.22 12.2 0.0 3.3 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 ORY09762.1 - 7.6e-08 32.8 0.1 0.23 12.1 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 ORY09762.1 - 2.6e-07 30.8 1.7 0.062 13.8 0.1 3.2 2 1 1 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 ORY09762.1 - 6.5e-06 26.3 0.1 0.052 13.9 0.0 2.6 3 0 0 3 3 3 2 Ankyrin repeats (many copies) NACHT PF05729.12 ORY09763.1 - 5.1e-06 26.5 0.1 6.5e-06 26.2 0.1 1.1 1 0 0 1 1 1 1 NACHT domain RCC1_2 PF13540.6 ORY09763.1 - 0.2 11.5 0.1 6.2 6.7 0.0 2.3 2 0 0 2 2 2 0 Regulator of chromosome condensation (RCC1) repeat Glyco_hydro_18 PF00704.28 ORY09764.1 - 8.4e-86 288.5 0.2 9.8e-86 288.3 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DnaJ PF00226.31 ORY09765.1 - 3.8e-07 30.1 0.3 8.5e-07 29.0 0.3 1.7 1 0 0 1 1 1 1 DnaJ domain Abhydrolase_6 PF12697.7 ORY09767.1 - 4.6e-16 60.1 3.9 5.6e-16 59.8 3.9 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_8 PF06259.12 ORY09767.1 - 0.027 14.1 0.0 0.06 13.0 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase PGAP1 PF07819.13 ORY09767.1 - 0.031 14.0 0.0 0.058 13.1 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Peptidase_S9 PF00326.21 ORY09767.1 - 0.055 12.9 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Thioesterase PF00975.20 ORY09767.1 - 0.18 11.9 0.0 0.86 9.7 0.0 1.9 3 0 0 3 3 3 0 Thioesterase domain zf-C2H2_6 PF13912.6 ORY09770.1 - 0.001 19.0 1.3 0.13 12.3 0.4 2.8 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 ORY09770.1 - 0.022 14.9 1.4 0.033 14.3 0.4 1.8 2 0 0 2 2 2 0 Aberrant zinc-finger zf-C2H2 PF00096.26 ORY09770.1 - 0.023 15.1 1.4 0.023 15.1 1.4 4.2 3 1 1 4 4 4 0 Zinc finger, C2H2 type DUF4795 PF16043.5 ORY09770.1 - 0.11 12.0 8.9 0.098 12.2 5.5 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) PilJ PF13675.6 ORY09770.1 - 0.44 10.6 3.5 0.63 10.1 0.2 2.7 2 1 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term XhlA PF10779.9 ORY09770.1 - 0.82 9.9 7.1 1.7 8.9 0.5 3.7 3 1 0 3 3 3 0 Haemolysin XhlA KapB PF08810.10 ORY09770.1 - 1.6 9.0 4.9 4.7 7.4 0.0 3.5 3 2 1 4 4 4 0 Kinase associated protein B Baculo_PEP_C PF04513.12 ORY09770.1 - 1.6 8.7 10.3 2.8 8.0 0.3 3.3 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus CdvA PF18822.1 ORY09770.1 - 1.7 8.5 9.7 1.1 9.1 2.4 3.0 2 1 0 3 3 3 0 CdvA-like coiled-coil domain Phage_Mu_Gam PF07352.12 ORY09770.1 - 4.1 7.3 9.9 1.4 8.8 0.1 3.5 4 0 0 4 4 4 0 Bacteriophage Mu Gam like protein DUF2434 PF10361.9 ORY09771.1 - 9.9e-129 428.5 7.9 1.3e-128 428.2 7.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2434) bMG6 PF17962.1 ORY09771.1 - 0.024 14.8 1.7 3.2 8.0 0.1 2.4 2 0 0 2 2 2 0 Bacterial macroglobulin domain 6 DUF2516 PF10724.9 ORY09771.1 - 0.11 12.8 1.5 0.33 11.3 1.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2516) CBS PF00571.28 ORY09772.1 - 5.4e-20 71.6 3.0 1.4e-06 28.7 0.0 5.1 5 0 0 5 5 5 4 CBS domain zf-RING_2 PF13639.6 ORY09773.1 - 7.4e-10 39.0 5.6 1.4e-09 38.2 5.6 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 ORY09773.1 - 5.6e-08 32.5 4.7 9.6e-08 31.7 4.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 ORY09773.1 - 2.1e-07 30.7 2.3 3.5e-07 30.0 2.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 ORY09773.1 - 9.3e-07 29.0 4.4 3.1e-06 27.4 4.4 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 ORY09773.1 - 3.9e-06 26.6 5.8 6.7e-06 25.9 5.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 ORY09773.1 - 9.6e-05 22.2 3.9 0.00016 21.4 3.9 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 ORY09773.1 - 0.0031 17.2 3.8 0.0065 16.2 3.8 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-ANAPC11 PF12861.7 ORY09773.1 - 0.048 13.7 1.8 0.15 12.1 1.8 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 ORY09773.1 - 0.32 11.0 3.8 0.74 9.8 3.8 1.7 1 0 0 1 1 1 0 zinc-RING finger domain HAD_SAK_1 PF10307.9 ORY09774.1 - 3.4e-74 249.1 0.2 5.2e-74 248.5 0.2 1.3 1 0 0 1 1 1 1 HAD domain family 1 in Swiss Army Knife RNA repair proteins Ribonuclease_T2 PF00445.18 ORY09775.1 - 1.1e-41 143.1 1.4 1.1e-41 143.1 1.4 1.4 2 0 0 2 2 2 1 Ribonuclease T2 family Epimerase PF01370.21 ORY09777.1 - 5e-15 55.6 0.2 3.4e-14 52.9 0.2 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ORY09777.1 - 1.7e-07 31.0 0.1 4.9e-07 29.5 0.1 1.8 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 ORY09777.1 - 2.8e-07 29.8 0.0 4.8e-07 29.1 0.0 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 ORY09777.1 - 5.6e-06 26.1 0.2 0.00049 19.7 0.3 2.7 2 1 1 3 3 3 1 NmrA-like family adh_short PF00106.25 ORY09777.1 - 4.7e-05 22.9 0.1 0.0001 21.9 0.1 1.6 1 1 0 1 1 1 1 short chain dehydrogenase F-box PF00646.33 ORY09778.1 - 4.6e-08 32.7 0.5 1.4e-07 31.2 0.3 1.9 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 ORY09778.1 - 1.9e-05 24.5 0.5 4.1e-05 23.4 0.5 1.6 1 0 0 1 1 1 1 F-box-like Folliculin PF11704.8 ORY09779.1 - 2.2e-56 190.7 0.0 3.2e-56 190.1 0.0 1.3 1 0 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport AAA PF00004.29 ORY09781.1 - 4.1e-18 66.1 0.0 8e-18 65.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 ORY09781.1 - 4e-06 27.3 0.0 1.2e-05 25.8 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 ORY09781.1 - 0.00096 18.9 0.0 0.002 17.9 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 ORY09781.1 - 0.0013 18.7 0.0 0.0032 17.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 ORY09781.1 - 0.0018 18.5 0.1 0.03 14.6 0.1 2.9 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.6 ORY09781.1 - 0.025 15.0 0.0 0.07 13.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 ORY09781.1 - 0.034 13.5 0.3 0.14 11.5 0.1 2.1 2 0 0 2 2 2 0 KaiC Mg_chelatase PF01078.21 ORY09781.1 - 0.055 12.8 0.4 0.2 11.0 0.2 2.0 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI DnaB_C PF03796.15 ORY09781.1 - 0.066 12.5 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_11 PF13086.6 ORY09781.1 - 0.072 12.9 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 ORY09781.1 - 0.12 12.0 0.0 0.28 10.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.14 ORY09781.1 - 0.12 12.5 0.3 0.62 10.2 0.0 2.1 2 1 0 2 2 1 0 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 ORY09781.1 - 0.12 12.9 0.0 0.45 11.1 0.0 2.0 2 0 0 2 2 1 0 AAA domain UCH PF00443.29 ORY09783.1 - 2.6e-49 168.0 0.8 3.5e-49 167.6 0.8 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 ORY09783.1 - 1.5e-24 87.2 6.2 7e-23 81.7 6.2 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 ORY09783.1 - 4e-07 30.3 0.0 1.6e-06 28.4 0.0 2.1 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein Peptidase_C98 PF15499.6 ORY09783.1 - 0.0013 18.3 1.0 1.4 8.4 0.0 3.3 3 0 0 3 3 3 2 Ubiquitin-specific peptidase-like, SUMO isopeptidase E6 PF00518.17 ORY09783.1 - 0.18 12.3 4.9 4.7 7.7 0.6 2.8 2 0 0 2 2 2 0 Early Protein (E6) zf_UBZ PF18439.1 ORY09783.1 - 5.2 6.8 10.6 1.5 8.5 0.1 3.9 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger Insulin_TMD PF17870.1 ORY09803.1 - 0.16 12.0 0.1 0.37 10.9 0.1 1.5 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment PHD PF00628.29 ORY09804.1 - 1.8e-09 37.3 5.1 3e-09 36.6 5.1 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 ORY09804.1 - 0.012 15.1 1.9 0.021 14.4 1.9 1.3 1 0 0 1 1 1 0 PHD-finger DnaJ PF00226.31 ORY09806.1 - 2.9e-15 56.1 0.3 7.9e-15 54.7 0.3 1.8 1 0 0 1 1 1 1 DnaJ domain Sec63 PF02889.16 ORY09806.1 - 2e-14 53.4 0.0 4.7e-14 52.2 0.0 1.6 1 1 0 1 1 1 1 Sec63 Brl domain RRN3 PF05327.11 ORY09806.1 - 0.75 8.3 2.4 1.1 7.7 2.4 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Pkinase PF00069.25 ORY09807.1 - 1.7e-50 171.9 0.0 4.4e-48 163.9 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORY09807.1 - 9.3e-29 100.5 0.0 1e-27 97.1 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Seadorna_VP7 PF07387.11 ORY09807.1 - 0.0012 17.9 0.1 0.0019 17.3 0.1 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Kinase-like PF14531.6 ORY09807.1 - 0.0015 17.9 0.0 0.0022 17.4 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 ORY09807.1 - 0.038 12.8 0.0 0.058 12.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 ORY09807.1 - 0.1 11.6 0.0 0.14 11.1 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain CbtA PF09490.10 ORY09807.1 - 0.13 12.0 0.4 0.2 11.4 0.4 1.2 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtA) Choline_kinase PF01633.20 ORY09808.1 - 2.3e-62 210.4 0.0 7.5e-62 208.7 0.0 1.8 2 0 0 2 2 2 1 Choline/ethanolamine kinase Mem_trans PF03547.18 ORY09808.1 - 4.5e-51 173.5 0.8 7.7e-51 172.7 0.8 1.3 1 0 0 1 1 1 1 Membrane transport protein Choline_kin_N PF04428.14 ORY09808.1 - 6e-18 64.3 0.0 1.6e-17 62.9 0.0 1.8 1 0 0 1 1 1 1 Choline kinase N terminus APH PF01636.23 ORY09808.1 - 3e-07 30.6 0.3 9e-07 29.0 0.3 1.8 1 0 0 1 1 1 1 Phosphotransferase enzyme family TFIIA PF03153.13 ORY09808.1 - 9.5 6.1 16.4 0.2 11.6 6.9 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DHH PF01368.20 ORY09811.1 - 5.1e-07 29.9 0.0 1.1e-06 28.9 0.0 1.5 1 0 0 1 1 1 1 DHH family NUDIX PF00293.28 ORY09812.1 - 9.1e-13 48.4 0.1 1.2e-12 48.0 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain Glyco_trans_2_3 PF13632.6 ORY09813.1 - 4.9e-23 82.1 2.1 4.9e-23 82.1 2.1 1.5 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 ORY09813.1 - 1.1e-11 45.0 0.0 1.9e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 ORY09813.1 - 0.075 13.5 0.0 0.15 12.6 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 2 Zn_clus PF00172.18 ORY09814.1 - 0.013 15.7 7.5 0.023 14.8 7.5 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_88 PF07470.13 ORY09815.1 - 1.6e-13 50.4 0.0 2.5e-13 49.8 0.0 1.4 1 1 0 1 1 1 1 Glycosyl Hydrolase Family 88 Glyco_tranf_2_3 PF13641.6 ORY09816.1 - 3.4e-18 66.4 0.0 4.4e-18 66.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 ORY09816.1 - 1.5e-10 41.1 0.0 2.6e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.6 ORY09816.1 - 1.5e-05 25.0 2.2 2.7e-05 24.2 2.2 1.5 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 ORY09816.1 - 0.00013 21.4 0.0 0.00091 18.7 0.0 2.2 1 1 1 2 2 2 1 Glycosyl transferase family 21 Oxysterol_BP PF01237.18 ORY09817.1 - 2e-135 451.4 0.1 3.1e-134 447.5 0.0 2.1 2 0 0 2 2 2 1 Oxysterol-binding protein Ank_5 PF13857.6 ORY09817.1 - 4.8e-16 58.6 0.1 2.3e-10 40.5 0.0 3.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 ORY09817.1 - 4.4e-15 56.0 0.0 2.6e-07 31.1 0.0 2.9 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) PH PF00169.29 ORY09817.1 - 6e-12 46.0 0.5 1.2e-11 45.1 0.5 1.5 1 0 0 1 1 1 1 PH domain Ank_3 PF13606.6 ORY09817.1 - 7.2e-12 44.4 0.1 0.00011 22.4 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 ORY09817.1 - 1.7e-11 44.4 0.0 4.8e-05 23.8 0.0 3.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 ORY09817.1 - 9.7e-11 41.6 0.0 0.0001 22.6 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat PH_8 PF15409.6 ORY09817.1 - 7.5e-07 29.3 0.9 7.5e-07 29.3 0.9 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.6 ORY09817.1 - 2.7e-05 24.5 2.7 0.00014 22.3 2.4 2.2 2 1 0 2 2 2 1 Pleckstrin homology domain ATP12 PF07542.11 ORY09818.1 - 1.2e-43 148.2 0.7 1.9e-43 147.6 0.7 1.3 1 0 0 1 1 1 1 ATP12 chaperone protein UnbV_ASPIC PF07593.12 ORY09818.1 - 0.12 12.3 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 ASPIC and UnbV Fungal_trans PF04082.18 ORY09819.1 - 8.1e-25 87.3 0.0 1.7e-23 83.0 0.0 2.3 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY09819.1 - 2.3e-07 30.8 8.9 4e-07 30.0 8.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain USP7_C2 PF14533.6 ORY09819.1 - 0.2 11.4 0.0 0.35 10.6 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-specific protease C-terminal MoaC PF01967.21 ORY09820.1 - 2.1e-49 167.1 0.2 3.6e-49 166.4 0.2 1.3 1 1 0 1 1 1 1 MoaC family Mob_synth_C PF06463.13 ORY09821.1 - 2.5e-35 121.2 0.0 3.3e-34 117.6 0.0 2.1 1 1 1 2 2 2 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 ORY09821.1 - 2.6e-25 89.8 0.0 6.7e-25 88.4 0.0 1.6 2 0 0 2 2 2 1 Radical SAM superfamily Fer4_12 PF13353.6 ORY09821.1 - 0.00013 22.2 0.0 0.0004 20.7 0.0 1.8 2 0 0 2 2 2 1 4Fe-4S single cluster domain GPI-anchored PF10342.9 ORY09823.1 - 0.2 12.4 6.1 0.27 12.0 0.4 3.1 4 1 0 4 4 4 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family PAN_4 PF14295.6 ORY09824.1 - 0.015 15.2 0.2 0.031 14.2 0.2 1.5 1 0 0 1 1 1 0 PAN domain adh_short_C2 PF13561.6 ORY09826.1 - 7.2e-44 150.1 0.0 1.3e-43 149.2 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY09826.1 - 1.3e-36 125.9 0.0 1.6e-36 125.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 ORY09826.1 - 0.00076 19.0 0.0 0.0013 18.3 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 ORY09826.1 - 0.012 14.7 0.0 0.018 14.2 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein TrkA_N PF02254.18 ORY09826.1 - 0.014 15.7 0.0 0.022 15.0 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain GDP_Man_Dehyd PF16363.5 ORY09826.1 - 0.029 13.8 0.1 0.042 13.3 0.1 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase 3HCDH_N PF02737.18 ORY09826.1 - 0.037 13.9 0.0 0.1 12.5 0.0 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 ORY09826.1 - 0.037 14.2 0.0 0.075 13.2 0.0 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Glyco_transf_4 PF13439.6 ORY09826.1 - 0.041 13.9 0.0 0.41 10.6 0.0 2.0 2 0 0 2 2 2 0 Glycosyltransferase Family 4 Transp_cyt_pur PF02133.15 ORY09827.1 - 1.3e-12 47.3 41.1 2e-12 46.6 41.1 1.4 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF5079 PF16882.5 ORY09827.1 - 0.32 10.9 5.0 0.18 11.7 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5079) DUF1294 PF06961.13 ORY09827.1 - 1.8 8.9 6.6 2.5 8.4 2.5 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1294) Lipase_GDSL_2 PF13472.6 ORY09828.1 - 4.9e-08 33.6 0.0 3.9e-07 30.6 0.0 2.2 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 ORY09828.1 - 0.055 13.4 3.2 0.61 10.0 3.2 2.6 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase Methyltransf_2 PF00891.18 ORY09830.1 - 1.9e-28 99.2 0.0 4.3e-28 98.0 0.0 1.5 2 0 0 2 2 2 1 O-methyltransferase domain Methyltransf_25 PF13649.6 ORY09830.1 - 0.00054 20.6 0.0 0.0024 18.6 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 ORY09830.1 - 0.014 14.9 0.0 0.028 14.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_18 PF12847.7 ORY09830.1 - 0.15 12.0 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DUF5345 PF17280.2 ORY09832.1 - 0.12 12.4 1.3 0.16 11.9 1.3 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5345) GMC_oxred_N PF00732.19 ORY09833.1 - 4.4e-52 177.3 0.0 6.1e-52 176.8 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 ORY09833.1 - 4.2e-36 124.6 0.0 1.1e-35 123.3 0.0 1.7 2 0 0 2 2 2 1 GMC oxidoreductase NAD_binding_8 PF13450.6 ORY09833.1 - 0.00051 20.2 0.1 0.0015 18.7 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ORY09833.1 - 0.0012 18.5 0.2 0.042 13.4 0.1 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 ORY09833.1 - 0.0013 17.9 0.0 0.002 17.3 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 ORY09833.1 - 0.011 15.0 0.0 0.032 13.5 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 ORY09833.1 - 0.05 12.4 0.0 0.081 11.8 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase GFO_IDH_MocA PF01408.22 ORY09834.1 - 1.4e-17 64.6 0.1 5.3e-17 62.7 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold HupE_UreJ PF04955.12 ORY09836.1 - 0.0042 16.6 1.7 0.0056 16.2 1.7 1.1 1 0 0 1 1 1 1 HupE / UreJ protein Aldolase_II PF00596.21 ORY09837.1 - 6.1e-49 166.5 0.1 7.9e-49 166.1 0.1 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Defensin_4 PF07936.12 ORY09837.1 - 0.12 12.3 0.5 0.23 11.4 0.5 1.4 1 0 0 1 1 1 0 Potassium-channel blocking toxin DUF4950 PF16308.5 ORY09837.1 - 0.2 11.6 0.0 0.28 11.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4950) GFA PF04828.14 ORY09839.1 - 2e-19 69.7 0.8 3.9e-19 68.8 0.8 1.5 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme DUF1996 PF09362.10 ORY09841.1 - 1.6e-80 270.5 0.9 2.1e-80 270.1 0.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Effector_1 PF04518.12 ORY09842.1 - 0.0048 16.1 3.5 0.0048 16.1 3.5 2.4 2 1 1 3 3 3 1 Effector from type III secretion system CCDC92 PF14916.6 ORY09842.1 - 0.0066 16.2 1.1 1.9 8.3 0.0 2.9 2 0 0 2 2 2 1 Coiled-coil domain of unknown function Filament PF00038.21 ORY09842.1 - 0.0092 15.6 25.6 0.11 12.0 10.2 2.8 2 1 1 3 3 3 2 Intermediate filament protein KASH_CCD PF14662.6 ORY09842.1 - 0.014 15.3 30.0 0.011 15.6 26.7 2.4 2 1 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH bZIP_1 PF00170.21 ORY09842.1 - 0.067 13.3 0.5 0.067 13.3 0.5 5.0 3 2 1 4 4 4 0 bZIP transcription factor SOGA PF11365.8 ORY09842.1 - 0.067 14.3 21.5 0.21 12.7 5.0 3.8 2 1 2 4 4 3 0 Protein SOGA Fez1 PF06818.15 ORY09842.1 - 0.14 12.6 28.3 2 8.8 15.7 2.6 1 1 1 2 2 2 0 Fez1 LPP PF04728.13 ORY09842.1 - 0.15 12.5 17.6 0.76 10.2 3.2 3.8 3 1 0 3 3 3 0 Lipoprotein leucine-zipper Ax_dynein_light PF10211.9 ORY09842.1 - 0.16 11.9 27.4 0.74 9.7 14.4 2.7 1 1 1 2 2 2 0 Axonemal dynein light chain DUF720 PF05302.11 ORY09842.1 - 0.32 10.8 7.2 0.22 11.4 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF720) HAP1_N PF04849.13 ORY09842.1 - 0.35 10.0 27.7 0.13 11.5 3.4 3.0 1 1 2 3 3 3 0 HAP1 N-terminal conserved region GAS PF13851.6 ORY09842.1 - 0.52 9.6 29.6 6.2 6.1 23.6 3.0 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding ERM PF00769.19 ORY09842.1 - 0.79 9.5 37.2 1.3 8.8 20.6 2.4 2 1 1 3 3 3 0 Ezrin/radixin/moesin family CASP_C PF08172.12 ORY09842.1 - 1 8.6 17.2 0.051 12.9 1.6 2.4 1 1 1 2 2 2 0 CASP C terminal YliH PF10799.8 ORY09842.1 - 1.1 9.2 4.9 1.6 8.7 2.5 2.3 1 1 1 2 2 2 0 Biofilm formation protein (YliH/bssR) TSC22 PF01166.18 ORY09842.1 - 1.4 9.3 15.0 4.3 7.7 0.2 5.3 3 2 3 6 6 6 0 TSC-22/dip/bun family Spc7 PF08317.11 ORY09842.1 - 2.2 7.1 29.5 12 4.7 26.8 2.4 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF1664 PF07889.12 ORY09842.1 - 2.5 8.1 14.5 1.7 8.7 0.7 3.9 2 1 3 5 5 5 0 Protein of unknown function (DUF1664) Mod_r PF07200.13 ORY09842.1 - 2.6 8.1 33.1 0.49 10.5 7.9 3.6 1 1 2 3 3 3 0 Modifier of rudimentary (Mod(r)) protein CAF1 PF04857.20 ORY09842.1 - 5.7 6.0 9.6 29 3.7 9.5 2.0 1 1 0 1 1 1 0 CAF1 family ribonuclease NYD-SP28_assoc PF14775.6 ORY09842.1 - 6.5 6.9 11.6 20 5.3 5.1 4.2 2 1 1 3 3 3 0 Sperm tail C-terminal domain SIMPL PF04402.14 ORY09842.1 - 7.6 6.9 11.5 0.65 10.4 3.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF541) FlaC_arch PF05377.11 ORY09842.1 - 7.8 7.0 13.3 2 8.9 0.7 4.9 3 1 2 5 5 5 0 Flagella accessory protein C (FlaC) YabA PF06156.13 ORY09842.1 - 8.2 7.1 22.1 1.4 9.6 3.3 3.8 1 1 3 4 4 4 0 Initiation control protein YabA Med13_C PF06333.12 ORY09845.1 - 0.0015 17.9 6.7 0.0017 17.7 6.7 1.1 1 0 0 1 1 1 1 Mediator complex subunit 13 C-terminal domain DUF3275 PF11679.8 ORY09845.1 - 0.35 10.8 7.9 0.086 12.8 2.5 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3275) Amidase PF01425.21 ORY09846.1 - 1.1e-78 265.2 0.3 9e-74 249.0 0.0 2.1 2 0 0 2 2 2 2 Amidase Esterase_phd PF10503.9 ORY09848.1 - 9.5e-22 77.6 0.7 1.5e-21 76.9 0.7 1.2 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 ORY09848.1 - 5.7e-05 22.7 1.8 0.00016 21.2 1.8 1.7 1 1 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 ORY09848.1 - 0.0028 17.4 1.5 0.0081 15.8 1.4 1.8 1 1 0 1 1 1 1 Putative esterase Peptidase_S10 PF00450.22 ORY09848.1 - 0.0036 16.8 0.1 0.0058 16.1 0.1 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase MFS_1 PF07690.16 ORY09849.1 - 4e-06 26.0 14.7 4.8e-06 25.7 14.7 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY09849.1 - 2.3e-05 23.5 4.2 2.8e-05 23.2 4.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY09850.1 - 8.2e-29 100.6 16.5 1.1e-28 100.2 16.5 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY09850.1 - 5.2e-10 38.8 4.9 6.3e-10 38.5 4.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_4 PF06779.14 ORY09850.1 - 3.3e-06 26.6 7.0 4e-06 26.4 7.0 1.1 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB TRI12 PF06609.13 ORY09850.1 - 0.00073 18.1 2.2 0.00089 17.8 2.2 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 ORY09850.1 - 0.0029 16.1 5.4 0.0029 16.1 5.4 1.6 1 1 1 2 2 2 1 Transmembrane secretion effector MFS_2 PF13347.6 ORY09850.1 - 0.0091 14.6 5.3 0.011 14.3 5.3 1.1 1 0 0 1 1 1 1 MFS/sugar transport protein PolC_DP2 PF03833.13 ORY09850.1 - 0.082 10.8 0.0 0.1 10.4 0.0 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 UPF0164 PF03687.13 ORY09850.1 - 0.12 11.2 0.0 0.2 10.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0164) Trp_DMAT PF11991.8 ORY09851.1 - 3.6e-87 293.1 0.0 5e-87 292.7 0.0 1.2 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase Beta-lactamase PF00144.24 ORY09852.1 - 9.8e-22 77.6 0.0 5.2e-15 55.5 0.0 2.1 1 1 1 2 2 2 2 Beta-lactamase Peptidase_S13 PF02113.15 ORY09852.1 - 0.22 10.2 0.2 0.31 9.7 0.2 1.1 1 0 0 1 1 1 0 D-Ala-D-Ala carboxypeptidase 3 (S13) family DUF3176 PF11374.8 ORY09853.1 - 1.7e-17 63.6 0.1 2.6e-17 62.9 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) Cu-oxidase_3 PF07732.15 ORY09854.1 - 7.4e-43 145.3 3.9 8.3e-43 145.2 1.5 2.4 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 ORY09854.1 - 1.2e-37 128.6 4.5 2.5e-33 114.7 0.2 2.9 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.22 ORY09854.1 - 3.6e-29 101.9 0.2 5.1e-28 98.2 0.0 2.5 2 0 0 2 2 2 1 Multicopper oxidase E1_DerP2_DerF2 PF02221.15 ORY09854.1 - 0.032 14.6 0.2 5.6 7.4 0.0 2.4 2 0 0 2 2 2 0 ML domain HET PF06985.11 ORY09855.1 - 6.3e-21 75.3 0.0 2e-20 73.6 0.0 1.9 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) YjbH PF06082.11 ORY09857.1 - 0.025 13.4 0.1 0.032 13.1 0.1 1.0 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH DUF3806 PF12713.7 ORY09861.1 - 0.23 11.3 0.1 1.3 8.8 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3806) zf-C2H2 PF00096.26 ORY09862.1 - 0.00017 21.8 3.2 0.00017 21.8 3.2 4.2 4 0 0 4 4 4 1 Zinc finger, C2H2 type PRKG1_interact PF15898.5 ORY09862.1 - 0.0058 17.5 0.2 0.0058 17.5 0.2 2.8 2 0 0 2 2 2 1 cGMP-dependent protein kinase interacting domain zf-C2H2_4 PF13894.6 ORY09862.1 - 0.0063 17.3 2.6 0.0063 17.3 2.6 4.9 5 0 0 5 5 5 1 C2H2-type zinc finger zf-H2C2_5 PF13909.6 ORY09862.1 - 0.015 15.1 12.3 0.18 11.6 2.1 4.1 4 0 0 4 4 4 0 C2H2-type zinc-finger domain C1_4 PF07975.12 ORY09862.1 - 0.034 14.4 4.9 1.5 9.1 0.1 3.0 2 0 0 2 2 2 0 TFIIH C1-like domain Chalcone PF02431.15 ORY09862.1 - 0.051 13.0 0.1 0.086 12.2 0.1 1.3 1 0 0 1 1 1 0 Chalcone-flavanone isomerase DUF4686 PF15742.5 ORY09862.1 - 0.57 9.2 4.2 1.1 8.3 0.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4686) Stig1 PF04885.13 ORY09872.1 - 0.00022 21.7 2.5 0.00054 20.5 2.5 1.6 1 0 0 1 1 1 1 Stigma-specific protein, Stig1 DUF410 PF04190.13 ORY09874.1 - 6.2e-92 308.0 0.0 7.5e-92 307.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF410) Sacchrp_dh_C PF16653.5 ORY09875.1 - 4.3e-97 325.4 0.0 8.7e-97 324.4 0.0 1.5 1 1 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 ORY09875.1 - 7.8e-25 87.6 0.5 1.4e-24 86.8 0.5 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 ORY09875.1 - 3.7e-08 33.5 0.1 7.2e-08 32.6 0.1 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase IlvN PF07991.12 ORY09875.1 - 3e-05 23.6 0.5 0.00045 19.8 0.1 2.7 2 1 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_10 PF13460.6 ORY09875.1 - 5.8e-05 23.1 0.1 9.7e-05 22.3 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding AlaDh_PNT_C PF01262.21 ORY09875.1 - 0.0016 17.8 0.2 0.0025 17.2 0.2 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain adh_short PF00106.25 ORY09875.1 - 0.0064 16.0 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_7 PF13241.6 ORY09875.1 - 0.016 15.6 0.2 0.033 14.6 0.2 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding TrkA_N PF02254.18 ORY09875.1 - 0.028 14.7 0.5 0.047 13.9 0.5 1.3 1 0 0 1 1 1 0 TrkA-N domain Sec15 PF04091.12 ORY09876.1 - 8.3e-106 354.0 5.1 8.3e-106 354.0 5.1 2.1 2 1 0 2 2 2 1 Exocyst complex subunit Sec15-like Sec8_exocyst PF04048.14 ORY09876.1 - 3.7e-06 26.9 2.8 3.7e-06 26.9 2.8 2.1 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain COG2 PF06148.11 ORY09876.1 - 0.0024 18.0 4.9 0.0024 18.0 4.9 3.0 2 1 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 COG5 PF10392.9 ORY09876.1 - 0.041 14.1 6.1 0.027 14.6 2.4 2.6 2 1 0 2 2 2 0 Golgi transport complex subunit 5 DUF3510 PF12022.8 ORY09876.1 - 0.51 10.7 5.0 15 6.0 0.1 3.6 2 2 0 3 3 3 0 Domain of unknown function (DUF3510) Sec5 PF15469.6 ORY09876.1 - 0.68 9.7 10.9 0.098 12.5 2.8 2.8 3 1 0 3 3 3 0 Exocyst complex component Sec5 ApoLp-III PF07464.11 ORY09876.1 - 1.9 8.6 11.9 0.52 10.4 5.4 3.1 3 1 1 4 4 4 0 Apolipophorin-III precursor (apoLp-III) F_actin_bind PF08919.10 ORY09876.1 - 4.4 7.5 6.8 28 4.9 0.5 3.5 3 1 0 3 3 3 0 F-actin binding RAI1 PF08652.11 ORY09879.1 - 7e-21 74.2 0.0 1.3e-20 73.3 0.0 1.5 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease RRM_2 PF04059.12 ORY09881.1 - 9.3e-23 80.3 0.0 1.5e-22 79.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_1 PF00076.22 ORY09881.1 - 2e-05 24.3 0.0 0.00081 19.2 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4477 PF14780.6 ORY09885.1 - 0.016 14.8 1.1 1.2 8.7 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4477) Abhydrolase_5 PF12695.7 ORY09887.1 - 0.028 14.2 0.0 0.05 13.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family ER-remodelling PF14755.6 ORY09887.1 - 0.13 12.5 3.1 0.23 11.7 3.1 1.3 1 0 0 1 1 1 0 Intracellular membrane remodeller Lipase_3 PF01764.25 ORY09887.1 - 0.17 11.8 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Pneumo_att_G PF05539.11 ORY09887.1 - 0.43 10.1 5.4 0.69 9.4 5.4 1.2 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G DUF641 PF04859.12 ORY09889.1 - 0.015 15.6 2.0 0.015 15.6 2.0 9.4 5 3 4 9 9 9 0 Plant protein of unknown function (DUF641) DUF4745 PF15923.5 ORY09889.1 - 1.9 8.5 6.0 0.86 9.6 2.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4745) Pkinase PF00069.25 ORY09890.1 - 1.3e-57 195.2 0.0 7.4e-57 192.7 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY09890.1 - 2.1e-25 89.5 0.1 3.2e-24 85.6 0.1 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORY09890.1 - 0.0002 20.3 0.0 0.00032 19.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 ORY09890.1 - 0.0005 20.1 0.2 0.0015 18.5 0.2 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 ORY09890.1 - 0.001 18.5 0.1 0.0083 15.5 0.1 2.3 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FHA PF00498.26 ORY09890.1 - 0.0011 19.2 0.0 0.003 17.9 0.0 1.8 1 0 0 1 1 1 1 FHA domain YrbL-PhoP_reg PF10707.9 ORY09890.1 - 0.014 15.0 0.0 0.025 14.1 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL STE3 PF02076.15 ORY09891.1 - 3.7e-83 279.1 22.8 6.1e-83 278.4 22.8 1.3 1 0 0 1 1 1 1 Pheromone A receptor Tail_spike_N PF18668.1 ORY09891.1 - 0.058 13.3 0.4 0.62 10.0 0.0 2.5 2 0 0 2 2 2 0 Tail spike TSP1/Gp66 receptor binding N-terminal domain Abhydrolase_3 PF07859.13 ORY09894.1 - 1.7e-41 142.4 0.0 2.1e-41 142.1 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 ORY09894.1 - 0.03 13.2 0.0 0.063 12.1 0.0 1.5 1 1 0 1 1 1 0 Carboxylesterase family zf-MIZ PF02891.20 ORY09894.1 - 0.046 13.5 0.1 0.63 9.8 0.1 2.4 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger BAG6 PF12057.8 ORY09896.1 - 0.0046 16.6 0.2 0.011 15.4 0.2 1.6 1 0 0 1 1 1 1 BCL2-associated athanogene 6 SesA PF17107.5 ORY09896.1 - 0.053 13.7 0.2 0.12 12.6 0.0 1.7 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases DUF1048 PF06304.11 ORY09896.1 - 0.18 12.3 0.0 1.8 9.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1048) DNA_ligase_ZBD PF03119.16 ORY09896.1 - 0.19 11.8 7.1 0.34 11.0 7.1 1.4 1 0 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain zf-NADH-PPase PF09297.11 ORY09896.1 - 4.4 7.0 7.9 8.5 6.1 7.9 1.4 1 0 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain P5-ATPase PF12409.8 ORY09897.1 - 2.7e-38 130.9 0.0 5.7e-38 129.8 0.0 1.6 1 0 0 1 1 1 1 P5-type ATPase cation transporter E1-E2_ATPase PF00122.20 ORY09897.1 - 8.8e-30 103.6 0.2 3.2e-29 101.7 0.0 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 ORY09897.1 - 4.8e-16 59.7 0.1 1.6e-07 31.8 0.0 3.3 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.21 ORY09897.1 - 2.2e-05 24.3 7.7 2.2e-05 24.3 7.7 2.0 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 ORY09897.1 - 0.00028 20.9 0.1 0.00061 19.8 0.1 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 ORY09897.1 - 0.017 14.8 0.0 0.044 13.5 0.0 1.7 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 ORY09897.1 - 0.24 11.1 0.0 9.6 5.8 0.0 2.2 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase DUF3325 PF11804.8 ORY09897.1 - 0.49 10.6 4.0 0.15 12.2 0.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3325) EspB PF05802.11 ORY09898.1 - 0.24 11.4 2.2 0.27 11.2 2.2 1.1 1 0 0 1 1 1 0 Enterobacterial EspB protein WD40 PF00400.32 ORY09899.1 - 1.8e-18 66.5 13.8 0.00064 20.5 0.2 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY09899.1 - 0.00026 21.3 0.1 2.8 8.3 0.0 3.5 1 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ORY09899.1 - 0.0008 18.2 0.1 0.051 12.2 0.1 3.1 2 1 2 4 4 4 1 Nucleoporin Nup120/160 WD40_like PF17005.5 ORY09899.1 - 0.014 14.8 0.0 0.22 10.8 0.0 2.2 2 0 0 2 2 2 0 WD40-like domain Nucleoporin_N PF08801.11 ORY09899.1 - 0.027 13.2 0.0 0.11 11.2 0.0 1.9 1 1 0 2 2 2 0 Nup133 N terminal like DnaJ_C PF01556.18 ORY09900.1 - 7.8e-36 123.4 1.3 1e-35 123.0 1.3 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 ORY09900.1 - 2.8e-29 101.0 2.0 5.2e-29 100.2 2.0 1.5 1 0 0 1 1 1 1 DnaJ domain DKCLD PF08068.12 ORY09901.1 - 2.2e-30 104.5 0.1 1.1e-28 99.0 0.1 2.7 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_C_2 PF16198.5 ORY09901.1 - 8.9e-24 83.4 0.6 1.8e-23 82.4 0.6 1.5 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain TruB_N PF01509.18 ORY09901.1 - 2.8e-23 82.9 0.3 2.9e-20 73.2 0.3 3.4 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.20 ORY09901.1 - 2.3e-20 72.3 0.8 4.5e-20 71.4 0.8 1.5 1 0 0 1 1 1 1 PUA domain RNA_polI_A34 PF08208.11 ORY09901.1 - 0.018 15.2 24.5 0.031 14.3 24.5 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 UPF0113 PF03657.13 ORY09901.1 - 0.11 12.7 0.0 0.31 11.4 0.0 1.7 1 0 0 1 1 1 0 UPF0113 PUA domain ASFV_J13L PF05568.11 ORY09901.1 - 0.15 11.8 0.3 0.23 11.2 0.3 1.3 1 0 0 1 1 1 0 African swine fever virus J13L protein VIR_N PF15912.5 ORY09901.1 - 1.8 8.1 9.5 2.5 7.6 9.5 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal RR_TM4-6 PF06459.12 ORY09901.1 - 3.1 7.5 13.7 4.1 7.1 13.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 R3H PF01424.22 ORY09902.1 - 8.5e-10 38.5 0.0 1.6e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 R3H domain RRM_1 PF00076.22 ORY09902.1 - 1.2e-05 25.0 0.1 3e-05 23.7 0.1 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MIase PF02426.16 ORY09902.1 - 0.056 13.6 0.1 1.2 9.4 0.0 2.3 2 0 0 2 2 2 0 Muconolactone delta-isomerase GYF PF02213.16 ORY09903.1 - 1e-06 28.3 0.7 2.1e-06 27.3 0.1 1.8 2 0 0 2 2 2 1 GYF domain UFD1 PF03152.14 ORY09904.1 - 3.7e-71 238.2 0.0 4.6e-71 237.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 Striatin PF08232.12 ORY09906.1 - 4.9e-46 157.1 6.0 4.9e-46 157.1 6.0 2.1 2 0 0 2 2 2 1 Striatin family WD40 PF00400.32 ORY09906.1 - 2e-23 82.2 21.3 0.0002 22.1 0.2 8.5 8 1 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY09906.1 - 1.4e-05 25.3 0.0 0.63 10.4 0.0 4.5 3 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain PXA PF02194.15 ORY09906.1 - 0.02 14.9 0.3 0.036 14.0 0.3 1.3 1 0 0 1 1 1 0 PXA domain KLRAQ PF10205.9 ORY09906.1 - 0.097 12.9 1.1 0.19 12.0 1.1 1.4 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein Ge1_WD40 PF16529.5 ORY09906.1 - 0.14 11.1 0.0 8.2 5.3 0.0 3.0 3 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein CCDC73 PF15818.5 ORY09906.1 - 6.2 4.5 10.5 0.83 7.4 4.7 1.9 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 73 family NLRC4_HD2 PF17776.1 ORY09907.1 - 0.083 13.4 0.6 0.1 13.1 0.6 1.0 1 0 0 1 1 1 0 NLRC4 helical domain HD2 Histone PF00125.24 ORY09908.1 - 4.2e-16 59.5 0.0 5.4e-16 59.2 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 ORY09908.1 - 1e-12 47.6 0.1 2e-12 46.6 0.1 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 ORY09908.1 - 0.00069 19.8 0.0 0.0011 19.2 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone EamA PF00892.20 ORY09910.1 - 3.5e-05 24.0 8.8 3.5e-05 24.0 8.8 2.2 2 0 0 2 2 2 1 EamA-like transporter family UPF0370 PF13980.6 ORY09910.1 - 0.14 12.2 0.1 0.47 10.5 0.1 1.9 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0370) PHO4 PF01384.20 ORY09910.1 - 6.1 5.8 17.4 0.15 11.1 8.1 2.3 1 1 1 2 2 2 0 Phosphate transporter family Thioredoxin PF00085.20 ORY09911.1 - 3.1e-06 27.1 0.1 2.6e-05 24.1 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin ARD PF03079.14 ORY09912.1 - 4.1e-43 147.3 0.4 4.8e-43 147.0 0.4 1.0 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 ORY09912.1 - 2.4e-08 33.6 0.2 3.8e-08 32.9 0.2 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 ORY09912.1 - 0.0091 15.9 0.1 0.014 15.3 0.1 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain HSF_DNA-bind PF00447.17 ORY09914.1 - 4.4e-28 97.7 0.5 8.9e-28 96.8 0.5 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding NPV_P10 PF05531.12 ORY09914.1 - 0.03 14.8 2.4 0.13 12.8 0.4 2.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Ets PF00178.22 ORY09914.1 - 0.067 13.7 0.0 0.18 12.3 0.0 1.7 1 0 0 1 1 1 0 Ets-domain BLOC1_2 PF10046.9 ORY09914.1 - 0.077 13.3 2.8 3 8.2 0.0 2.6 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DGF-1_4 PF11024.8 ORY09915.1 - 0.26 12.1 7.4 0.46 11.3 7.4 1.4 1 0 0 1 1 1 0 Dispersed gene family protein 1 of Trypanosoma cruzi region 4 TPT PF03151.16 ORY09916.1 - 1.9e-11 43.8 14.7 2.4e-11 43.5 14.7 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 ORY09916.1 - 1.7e-05 25.0 9.6 1.7e-05 25.0 9.6 2.2 2 0 0 2 2 2 2 EamA-like transporter family TMEM234 PF10639.9 ORY09916.1 - 0.014 15.4 4.7 0.083 12.9 1.0 2.5 2 0 0 2 2 2 0 Putative transmembrane family 234 Glyco_transf_8 PF01501.20 ORY09917.1 - 0.00071 19.2 0.4 0.0091 15.6 0.4 2.0 1 1 0 1 1 1 1 Glycosyl transferase family 8 PBP1_TM PF14812.6 ORY09918.1 - 0.061 13.7 4.3 0.26 11.7 1.1 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DSS1_SEM1 PF05160.13 ORY09918.1 - 0.11 12.6 9.0 0.25 11.4 3.4 2.4 2 0 0 2 2 2 0 DSS1/SEM1 family F-box PF00646.33 ORY09919.1 - 0.00085 19.1 2.0 0.0017 18.2 0.9 2.1 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 ORY09919.1 - 0.037 13.9 0.7 0.068 13.1 0.1 1.8 2 0 0 2 2 2 0 F-box-like Brix PF04427.18 ORY09921.1 - 3.1e-40 138.4 0.1 4e-40 138.0 0.1 1.1 1 0 0 1 1 1 1 Brix domain SNF2_N PF00176.23 ORY09922.1 - 1.8e-65 221.0 2.7 4.8e-65 219.6 2.7 1.7 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.6 ORY09922.1 - 2.5e-48 163.9 21.6 2.5e-48 163.9 21.6 4.4 4 1 0 4 4 4 1 DNA-binding domain Helicase_C PF00271.31 ORY09922.1 - 5.5e-20 71.8 0.0 1.4e-19 70.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY09922.1 - 2.5e-07 30.9 0.0 2.5e-07 30.9 0.0 2.7 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.29 ORY09922.1 - 0.0016 18.2 0.0 0.0045 16.8 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 ORY09922.1 - 0.003 16.8 0.0 0.003 16.8 0.0 3.4 4 1 0 4 4 4 1 Class II histone deacetylase complex subunits 2 and 3 Macro PF01661.21 ORY09923.1 - 6.7e-48 161.6 0.0 4.5e-23 81.5 0.1 2.5 2 0 0 2 2 2 2 Macro domain zf-C2H2_4 PF13894.6 ORY09923.1 - 0.036 14.9 2.8 41 5.4 0.0 4.3 3 0 0 3 3 3 0 C2H2-type zinc finger SFTA2 PF15210.6 ORY09924.1 - 0.019 14.9 0.0 0.05 13.5 0.0 1.6 1 0 0 1 1 1 0 Surfactant-associated protein 2 Hydrolase_4 PF12146.8 ORY09924.1 - 0.099 11.9 0.1 1.1 8.5 0.0 2.1 2 0 0 2 2 2 0 Serine aminopeptidase, S33 FapA PF03961.13 ORY09924.1 - 0.42 9.2 6.3 2.4 6.7 6.2 1.9 1 1 1 2 2 2 0 Flagellar Assembly Protein A GAS PF13851.6 ORY09924.1 - 0.45 9.8 6.7 1.7 8.0 5.0 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Syntaxin_2 PF14523.6 ORY09924.1 - 1.9 8.9 4.8 2.8 8.4 0.5 2.8 3 0 0 3 3 3 0 Syntaxin-like protein SMI1_KNR4 PF09346.10 ORY09925.1 - 1e-30 106.8 0.0 7.9e-30 104.0 0.0 2.1 1 1 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) Pept_tRNA_hydro PF01195.19 ORY09926.1 - 3.8e-34 118.1 0.0 5.1e-34 117.7 0.0 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase XPA_C PF05181.12 ORY09927.1 - 9.1e-25 86.4 1.6 1.6e-24 85.6 1.6 1.4 1 0 0 1 1 1 1 XPA protein C-terminus XPA_N PF01286.18 ORY09927.1 - 0.0031 17.5 0.4 0.0031 17.5 0.4 2.3 2 0 0 2 2 2 1 XPA protein N-terminal Histone_HNS PF00816.21 ORY09927.1 - 0.084 13.7 3.6 8.9 7.2 0.1 2.9 2 0 0 2 2 2 0 H-NS histone family Cut12 PF11500.8 ORY09928.1 - 1e-28 100.1 17.0 3.4e-28 98.4 16.7 2.0 1 1 0 1 1 1 1 Spindle pole body formation-associated protein Rootletin PF15035.6 ORY09928.1 - 0.0028 17.7 8.2 0.006 16.6 8.2 1.6 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion Spc7 PF08317.11 ORY09928.1 - 0.11 11.3 13.7 0.24 10.2 13.7 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF3304 PF11745.8 ORY09928.1 - 0.11 12.8 2.8 0.34 11.3 1.8 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3304) LicD PF04991.13 ORY09928.1 - 0.24 11.5 4.0 0.37 10.9 4.0 1.3 1 0 0 1 1 1 0 LicD family IFT57 PF10498.9 ORY09928.1 - 0.28 10.1 10.2 0.43 9.5 10.2 1.3 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Jnk-SapK_ap_N PF09744.9 ORY09928.1 - 1.4 9.1 13.0 3.9 7.7 13.0 1.8 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Exonuc_VII_L PF02601.15 ORY09928.1 - 1.4 8.4 9.5 3 7.3 9.5 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit Tho2 PF11262.8 ORY09928.1 - 1.5 8.0 7.2 2.7 7.1 7.2 1.5 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 TSNAXIP1_N PF15739.5 ORY09928.1 - 3.6 8.0 12.2 3 8.3 9.5 2.1 1 1 1 2 2 2 0 Translin-associated factor X-interacting N-terminus HGTP_anticodon2 PF12745.7 ORY09929.1 - 6.5e-77 258.6 0.0 6.5e-77 258.6 0.0 2.1 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs Pkinase PF00069.25 ORY09929.1 - 1.8e-75 253.7 0.0 7.8e-37 127.1 0.0 3.7 3 1 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 ORY09929.1 - 6.6e-48 163.2 0.0 3.4e-20 72.4 0.0 3.6 3 0 0 3 3 3 3 Protein tyrosine kinase RWD PF05773.22 ORY09929.1 - 2.6e-18 66.4 0.3 1.6e-17 63.9 0.0 2.4 2 0 0 2 2 2 1 RWD domain tRNA-synt_His PF13393.6 ORY09929.1 - 3.1e-11 43.1 1.0 1.6e-10 40.8 0.0 2.5 3 0 0 3 3 3 1 Histidyl-tRNA synthetase Kinase-like PF14531.6 ORY09929.1 - 0.00053 19.4 0.0 0.11 11.8 0.0 2.5 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 ORY09929.1 - 0.00055 19.9 2.1 0.0048 16.8 0.0 2.8 3 0 0 3 3 3 1 Phosphotransferase enzyme family FTA2 PF13095.6 ORY09929.1 - 0.048 13.3 3.2 0.95 9.0 0.0 3.2 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 DUF1682 PF07946.14 ORY09929.1 - 0.7 9.0 10.0 1.3 8.2 10.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Zn_clus PF00172.18 ORY09930.1 - 2.6e-09 37.0 9.5 2.6e-09 37.0 9.5 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain YscO PF07321.12 ORY09930.1 - 0.0016 18.4 2.6 0.0016 18.4 2.6 2.1 2 0 0 2 2 2 1 Type III secretion protein YscO Tmemb_cc2 PF10267.9 ORY09930.1 - 0.0072 15.5 1.8 0.0098 15.1 1.8 1.1 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein Cnn_1N PF07989.11 ORY09930.1 - 0.0088 16.2 2.2 0.026 14.6 2.2 1.8 1 0 0 1 1 1 1 Centrosomin N-terminal motif 1 SF-assemblin PF06705.11 ORY09930.1 - 0.0094 15.3 1.9 0.016 14.5 1.9 1.4 1 0 0 1 1 1 1 SF-assemblin/beta giardin NPV_P10 PF05531.12 ORY09930.1 - 0.019 15.4 2.0 0.042 14.3 2.0 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein TACC_C PF05010.14 ORY09930.1 - 0.02 14.7 5.5 0.036 13.9 5.5 1.5 1 1 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Phage_GP20 PF06810.11 ORY09930.1 - 0.02 14.7 4.1 0.02 14.7 4.1 1.7 2 0 0 2 2 2 0 Phage minor structural protein GP20 GrpE PF01025.19 ORY09930.1 - 0.094 12.4 3.6 0.16 11.6 3.6 1.3 1 0 0 1 1 1 0 GrpE ZapB PF06005.12 ORY09930.1 - 0.096 13.1 3.7 0.26 11.7 3.7 1.7 1 0 0 1 1 1 0 Cell division protein ZapB DivIC PF04977.15 ORY09930.1 - 0.096 12.5 4.5 0.26 11.1 4.4 1.8 1 1 0 1 1 1 0 Septum formation initiator TolA_bind_tri PF16331.5 ORY09930.1 - 0.13 12.3 5.5 0.26 11.4 5.5 1.5 1 0 0 1 1 1 0 TolA binding protein trimerisation GH115_C PF17829.1 ORY09930.1 - 0.17 11.7 1.3 2.8 7.7 0.3 2.4 2 1 0 2 2 2 0 Gylcosyl hydrolase family 115 C-terminal domain SlyX PF04102.12 ORY09930.1 - 0.22 12.1 5.3 0.55 10.9 5.3 1.7 1 0 0 1 1 1 0 SlyX FUSC PF04632.12 ORY09930.1 - 0.5 8.8 3.6 0.63 8.5 3.6 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Occludin_ELL PF07303.13 ORY09930.1 - 1 10.1 4.1 0.37 11.5 1.0 1.9 2 0 0 2 2 2 0 Occludin homology domain zf-C4pol PF14260.6 ORY09930.1 - 1.4 9.5 9.0 13 6.4 4.4 3.1 1 1 2 3 3 3 0 C4-type zinc-finger of DNA polymerase delta Uso1_p115_C PF04871.13 ORY09930.1 - 7.1 7.0 12.3 0.098 13.0 2.5 2.4 3 0 0 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region TRAUB PF08164.12 ORY09930.1 - 9.4 6.8 8.1 3.3 8.3 3.4 2.6 1 1 2 3 3 3 0 Apoptosis-antagonizing transcription factor, C-terminal ArgJ PF01960.18 ORY09931.1 - 9.8e-148 491.9 1.5 1.1e-147 491.7 1.5 1.0 1 0 0 1 1 1 1 ArgJ family GMC_oxred_N PF00732.19 ORY09932.1 - 2.1e-30 106.1 0.0 3.6e-28 98.8 0.0 2.2 2 0 0 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.13 ORY09932.1 - 1.1e-27 97.4 0.0 2.3e-27 96.3 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 ORY09932.1 - 0.0003 20.1 0.0 0.00055 19.3 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ORY09932.1 - 0.0042 16.2 0.0 0.04 13.0 0.1 2.0 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 ORY09932.1 - 0.0055 16.9 0.1 0.017 15.3 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 ORY09932.1 - 0.036 13.3 0.1 0.062 12.5 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 ORY09932.1 - 0.05 12.8 0.1 1.9 7.6 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 ORY09932.1 - 0.062 12.3 0.0 0.09 11.8 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein HI0933_like PF03486.14 ORY09932.1 - 0.13 11.0 0.6 0.2 10.3 0.0 1.6 2 0 0 2 2 2 0 HI0933-like protein ORC6 PF05460.13 ORY09933.1 - 5.4 6.2 12.9 0.95 8.7 6.1 2.3 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) F-box PF00646.33 ORY09935.1 - 0.0031 17.4 0.0 0.0072 16.2 0.0 1.6 1 0 0 1 1 1 1 F-box domain DUF3657 PF12394.8 ORY09935.1 - 0.091 13.3 0.9 0.19 12.3 0.1 1.9 2 0 0 2 2 2 0 Protein FAM135 Pro_isomerase PF00160.21 ORY09936.1 - 9e-37 126.8 0.0 1.7e-36 125.9 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ribosomal_S28e PF01200.18 ORY09946.1 - 0.0056 16.6 2.0 0.026 14.5 0.3 2.2 2 0 0 2 2 2 1 Ribosomal protein S28e HET PF06985.11 ORY09947.1 - 5e-31 108.0 3.1 6.3e-31 107.7 3.1 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Dak1 PF02733.17 ORY09948.1 - 2.9e-106 354.9 2.1 4.5e-106 354.2 2.1 1.2 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 ORY09948.1 - 1.4e-46 158.6 0.1 2.9e-46 157.5 0.1 1.6 1 0 0 1 1 1 1 DAK2 domain LSM PF01423.22 ORY09949.1 - 3.7e-18 65.0 0.1 5.1e-18 64.5 0.1 1.2 1 0 0 1 1 1 1 LSM domain GATA PF00320.27 ORY09950.1 - 0.015 14.9 9.9 0.46 10.1 2.9 2.5 2 0 0 2 2 2 0 GATA zinc finger DUF576 PF04507.12 ORY09951.1 - 0.24 10.8 0.5 0.48 9.8 0.5 1.4 1 0 0 1 1 1 0 Csa1 family YjbH PF06082.11 ORY09951.1 - 1.9 7.2 5.0 0.33 9.7 1.5 1.4 2 0 0 2 2 2 0 Exopolysaccharide biosynthesis protein YbjH RRM_1 PF00076.22 ORY09952.1 - 2.7e-62 206.5 0.0 5.2e-22 77.5 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 ORY09952.1 - 2.8e-11 43.1 0.0 7.7e-06 25.5 0.0 3.2 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 ORY09952.1 - 5.9e-11 42.1 0.0 0.0022 17.8 0.0 3.3 3 0 0 3 3 3 2 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 ORY09952.1 - 9e-06 25.6 0.0 0.46 10.5 0.0 3.5 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif RRM_8 PF11835.8 ORY09952.1 - 0.00026 21.1 0.0 0.1 12.8 0.0 2.4 2 0 0 2 2 2 2 RRM-like domain RRM_7 PF16367.5 ORY09952.1 - 0.00099 19.2 0.1 0.58 10.3 0.0 3.0 3 0 0 3 3 3 2 RNA recognition motif Cas_Cas2CT1978 PF09707.10 ORY09952.1 - 0.0021 18.1 0.0 1.2 9.2 0.0 2.4 2 0 0 2 2 2 2 CRISPR-associated protein (Cas_Cas2CT1978) SET_assoc PF11767.8 ORY09952.1 - 0.024 14.2 0.0 4.2 7.1 0.0 2.5 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated Limkain-b1 PF11608.8 ORY09952.1 - 0.04 14.0 0.2 8.5 6.5 0.0 2.8 3 0 0 3 3 3 0 Limkain b1 RRM_3 PF08777.11 ORY09952.1 - 0.12 12.4 0.0 2.7 8.1 0.0 2.6 3 0 0 3 3 3 0 RNA binding motif YjeF_N PF03853.15 ORY09953.1 - 1.1e-39 136.1 0.1 1.6e-39 135.5 0.1 1.3 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.10 ORY09953.1 - 4.6e-05 24.2 0.3 4.6e-05 24.2 0.3 2.3 2 0 0 2 2 2 1 FDF domain FMN_red PF03358.15 ORY09953.1 - 0.13 12.0 0.1 0.27 11.0 0.1 1.4 1 0 0 1 1 1 0 NADPH-dependent FMN reductase DUF1749 PF08538.10 ORY09954.1 - 4.2e-84 282.2 0.0 4.7e-84 282.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.7 ORY09954.1 - 0.0015 19.1 0.0 0.002 18.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORY09954.1 - 0.1 11.9 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 ORY09954.1 - 0.17 11.7 0.0 0.4 10.5 0.0 1.6 2 0 0 2 2 2 0 Serine hydrolase adh_short_C2 PF13561.6 ORY09955.1 - 1e-53 182.3 0.5 1.5e-53 181.8 0.5 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY09955.1 - 1.8e-44 151.5 2.0 2.3e-44 151.2 2.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORY09955.1 - 2e-12 47.4 0.3 2.5e-12 47.1 0.3 1.1 1 0 0 1 1 1 1 KR domain AdoHcyase_NAD PF00670.21 ORY09955.1 - 0.0094 16.0 0.4 0.02 15.0 0.4 1.6 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain CABS1 PF15367.6 ORY09955.1 - 0.0097 15.1 0.0 0.014 14.5 0.0 1.2 1 0 0 1 1 1 1 Calcium-binding and spermatid-specific protein 1 SurE PF01975.17 ORY09957.1 - 6.7e-51 172.8 0.0 9.1e-51 172.4 0.0 1.2 1 0 0 1 1 1 1 Survival protein SurE Transglut_core PF01841.19 ORY09958.1 - 3.1e-11 43.7 0.0 5.7e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF553 PF04473.12 ORY09958.1 - 0.00032 20.2 0.0 0.011 15.3 0.0 2.4 2 1 0 2 2 2 1 Transglutaminase-like domain Gln_amidase PF15644.6 ORY09958.1 - 0.013 16.5 0.0 0.032 15.2 0.0 1.8 1 1 0 1 1 1 0 Papain fold toxin 1, glutamine deamidase Zn_clus PF00172.18 ORY09959.1 - 0.00066 19.8 12.2 0.0012 18.9 12.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CHZ PF09649.10 ORY09959.1 - 0.0011 18.4 0.2 0.0011 18.4 0.2 2.9 3 1 1 4 4 4 1 Histone chaperone domain CHZ Cyclin_N PF00134.23 ORY09961.1 - 7.2e-45 151.8 0.3 1.2e-44 151.1 0.3 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 ORY09961.1 - 3.6e-34 117.4 0.4 9.9e-34 116.0 0.0 1.9 2 0 0 2 2 2 1 Cyclin, C-terminal domain NT5C PF06941.12 ORY09961.1 - 0.14 12.1 0.2 0.36 10.7 0.2 1.7 1 0 0 1 1 1 0 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) LSM PF01423.22 ORY09962.1 - 9.6e-18 63.6 0.1 1.3e-17 63.3 0.1 1.2 1 0 0 1 1 1 1 LSM domain Kinetochor_Ybp2 PF08568.10 ORY09963.1 - 1.2e-138 463.4 0.2 1.5e-138 463.1 0.2 1.0 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin adh_short_C2 PF13561.6 ORY09965.1 - 3.9e-64 216.4 3.9 4.9e-64 216.1 3.9 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY09965.1 - 5.5e-50 169.5 1.1 7.5e-50 169.1 1.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORY09965.1 - 9.1e-15 55.0 0.9 9.1e-15 55.0 0.9 1.5 1 1 1 2 2 2 1 KR domain 3HCDH_N PF02737.18 ORY09965.1 - 0.024 14.5 0.2 0.047 13.6 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ubie_methyltran PF01209.18 ORY09965.1 - 0.046 13.0 0.0 0.72 9.1 0.0 2.1 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Ldh_1_N PF00056.23 ORY09965.1 - 0.057 13.5 0.1 0.13 12.4 0.1 1.6 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain TPM_phosphatase PF04536.14 ORY09965.1 - 0.1 12.8 0.1 0.17 12.0 0.1 1.4 1 0 0 1 1 1 0 TPM domain Epimerase PF01370.21 ORY09965.1 - 0.12 11.8 0.2 0.38 10.2 0.2 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Methyltransf_12 PF08242.12 ORY09965.1 - 0.15 12.9 0.0 0.31 11.8 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain AtuA PF07287.11 ORY09966.1 - 5.8e-123 410.1 0.4 6.9e-123 409.8 0.4 1.1 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA Phage_TTP_12 PF16461.5 ORY09966.1 - 0.011 15.4 0.1 0.02 14.6 0.1 1.3 1 0 0 1 1 1 0 Lambda phage tail tube protein, TTP adh_short PF00106.25 ORY09966.1 - 0.11 11.9 0.9 3.5 7.0 0.1 2.7 3 0 0 3 3 3 0 short chain dehydrogenase YEATS PF03366.16 ORY09967.1 - 4.9e-20 71.3 0.1 9.7e-20 70.3 0.1 1.5 1 0 0 1 1 1 1 YEATS family BET PF17035.5 ORY09967.1 - 8.8e-06 25.8 0.2 1.7e-05 24.9 0.2 1.4 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation Ran_BP1 PF00638.18 ORY09968.1 - 1.7e-49 167.1 1.4 3.3e-49 166.2 1.4 1.5 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.23 ORY09968.1 - 0.00027 20.8 0.2 0.0018 18.2 0.2 2.0 1 1 0 1 1 1 1 WH1 domain VID27_PH PF17747.1 ORY09968.1 - 0.00049 20.3 0.0 0.00072 19.8 0.0 1.2 1 0 0 1 1 1 1 VID27 PH-like domain CK2S PF15011.6 ORY09968.1 - 0.052 13.4 0.3 0.091 12.6 0.3 1.3 1 0 0 1 1 1 0 Casein Kinase 2 substrate ALMT PF11744.8 ORY09968.1 - 0.4 9.5 3.3 0.48 9.2 3.3 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter CDC27 PF09507.10 ORY09968.1 - 0.48 9.7 17.6 0.61 9.4 17.6 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Vfa1 PF08432.10 ORY09968.1 - 5.6 7.3 11.7 11 6.3 11.7 1.5 1 1 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Baculo_PEP_C PF04513.12 ORY09969.1 - 0.013 15.5 0.8 0.028 14.5 0.8 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3037 PF11236.8 ORY09969.1 - 0.19 12.1 0.5 0.68 10.4 0.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3037) ApoLp-III PF07464.11 ORY09969.1 - 0.46 10.6 12.4 0.037 14.1 4.2 2.2 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Glyco_transf_15 PF01793.16 ORY09970.1 - 3.7e-97 325.5 9.2 4.4e-96 321.9 9.2 1.9 1 1 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase DUF2721 PF11026.8 ORY09970.1 - 0.13 12.2 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) DUF4604 PF15377.6 ORY09971.1 - 2.1e-21 77.1 14.6 2.4e-21 76.9 14.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) BTB PF00651.31 ORY09972.1 - 1.8e-10 41.0 0.0 2.1e-10 40.8 0.0 1.1 1 0 0 1 1 1 1 BTB/POZ domain FA_desaturase PF00487.24 ORY09973.1 - 0.0025 17.7 0.5 0.0039 17.1 0.5 1.2 1 0 0 1 1 1 1 Fatty acid desaturase RNA_pol_Rpb1_R PF05001.13 ORY09975.1 - 1.1 9.8 9.8 0.3 11.5 3.7 3.3 2 0 0 2 2 2 0 RNA polymerase Rpb1 C-terminal repeat Amidase PF01425.21 ORY09976.1 - 4e-83 279.9 2.4 9.4e-83 278.7 2.4 1.6 1 1 0 1 1 1 1 Amidase OPT PF03169.15 ORY09977.1 - 5.8e-161 537.2 53.1 6.5e-161 537.0 53.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Egh16-like PF11327.8 ORY09978.1 - 5.5e-57 193.1 12.6 7.5e-57 192.7 12.6 1.2 1 0 0 1 1 1 1 Egh16-like virulence factor I-set PF07679.16 ORY09978.1 - 0.17 12.0 0.0 0.35 11.0 0.0 1.4 1 0 0 1 1 1 0 Immunoglobulin I-set domain DUF1765 PF08578.10 ORY09979.1 - 0.08 13.4 0.0 0.08 13.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1765) ASFV_p27 PF06556.11 ORY09980.1 - 0.12 12.4 0.6 0.18 11.9 0.4 1.4 1 1 0 1 1 1 0 IAP-like protein p27 C-terminus Chal_sti_synt_N PF00195.19 ORY09983.1 - 8.1e-23 81.0 0.8 1.2e-22 80.4 0.8 1.2 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain Chal_sti_synt_C PF02797.15 ORY09983.1 - 9.9e-18 64.6 0.0 1.8e-17 63.8 0.0 1.3 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain ACP_syn_III_C PF08541.10 ORY09983.1 - 5.2e-08 33.0 0.0 1.6e-07 31.4 0.0 1.9 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.10 ORY09983.1 - 4.9e-06 26.3 1.8 1.1e-05 25.2 1.8 1.5 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III FAE1_CUT1_RppA PF08392.12 ORY09983.1 - 0.00041 19.7 0.0 0.00057 19.3 0.0 1.2 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein ABC2_membrane PF01061.24 ORY09984.1 - 0.078 12.4 4.1 0.48 9.8 1.5 2.1 2 0 0 2 2 2 0 ABC-2 type transporter SirB PF04247.12 ORY09984.1 - 5.5 7.1 6.3 1.1 9.4 2.1 1.9 2 0 0 2 2 2 0 Invasion gene expression up-regulator, SirB ABM PF03992.16 ORY09985.1 - 4e-08 33.2 0.0 1.4e-07 31.6 0.0 1.8 3 0 0 3 3 3 1 Antibiotic biosynthesis monooxygenase PAN_4 PF14295.6 ORY09987.1 - 3.1e-08 33.4 8.6 0.00066 19.5 0.3 2.9 3 0 0 3 3 3 2 PAN domain PAN_1 PF00024.26 ORY09987.1 - 5.7e-08 32.6 2.0 0.0015 18.4 0.3 2.4 2 0 0 2 2 2 2 PAN domain PAN_3 PF08277.12 ORY09987.1 - 4.1e-07 29.7 7.9 0.00062 19.5 0.5 2.7 3 0 0 3 3 3 2 PAN-like domain PAN_2 PF08276.11 ORY09987.1 - 0.25 11.5 7.2 3.1 8.0 0.3 2.4 2 0 0 2 2 2 0 PAN-like domain HET PF06985.11 ORY09988.1 - 8.2e-27 94.4 0.6 4e-26 92.1 0.0 2.6 3 0 0 3 3 3 1 Heterokaryon incompatibility protein (HET) Glyco_transf_90 PF05686.12 ORY09989.1 - 1.4e-20 73.6 0.4 4.9e-15 55.3 0.4 2.5 2 1 0 2 2 2 2 Glycosyl transferase family 90 Tir_receptor_C PF07489.11 ORY09990.1 - 0.13 12.2 0.0 0.2 11.6 0.0 1.2 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus HET PF06985.11 ORY09991.1 - 3.4e-27 95.6 0.0 4.8e-27 95.1 0.0 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) FAD_binding_3 PF01494.19 ORY09992.1 - 3.6e-12 46.2 0.2 5.5e-06 25.9 0.1 3.1 3 0 0 3 3 3 3 FAD binding domain Pyr_redox_2 PF07992.14 ORY09992.1 - 1.1e-08 34.6 0.0 0.001 18.4 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ORY09992.1 - 6.9e-05 22.1 0.0 0.00014 21.1 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 ORY09992.1 - 8.6e-05 22.7 0.0 0.00042 20.5 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 ORY09992.1 - 0.0006 20.3 0.0 1.6 9.3 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 ORY09992.1 - 0.0034 16.3 0.0 0.53 9.1 0.0 2.5 3 0 0 3 3 3 2 Tryptophan halogenase HI0933_like PF03486.14 ORY09992.1 - 0.0048 15.6 0.0 0.056 12.1 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 ORY09992.1 - 0.012 15.0 0.0 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.22 ORY09992.1 - 0.028 13.5 0.0 0.041 13.0 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 ORY09992.1 - 0.057 12.7 0.0 0.37 10.0 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ORY09992.1 - 0.057 13.0 0.0 1.1 8.7 0.0 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase Amino_oxidase PF01593.24 ORY09992.1 - 0.071 12.4 0.0 3 7.0 0.0 2.3 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Rubredoxin_2 PF18073.1 ORY09993.1 - 0.076 12.7 0.9 0.24 11.1 0.7 2.0 2 0 0 2 2 2 0 Rubredoxin metal binding domain adh_short PF00106.25 ORY09994.1 - 8.3e-20 71.1 0.0 7e-16 58.3 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 ORY09994.1 - 3.6e-15 56.2 0.0 1.1e-11 44.8 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY09994.1 - 7.2e-05 22.8 0.2 0.00011 22.2 0.2 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 ORY09994.1 - 0.0041 16.3 0.1 0.0055 15.9 0.1 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DUF4150 PF13665.6 ORY09994.1 - 0.036 14.2 0.0 0.078 13.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4150) Sugar_tr PF00083.24 ORY09995.1 - 3e-80 270.3 24.8 3.5e-80 270.1 24.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY09995.1 - 4.4e-23 81.8 33.4 6.9e-19 68.0 15.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 ORY09995.1 - 0.0011 17.5 1.6 0.0011 17.5 1.6 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 ORY09995.1 - 0.023 13.0 7.0 0.012 13.9 1.3 2.4 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family p450 PF00067.22 ORY09996.1 - 5.5e-60 203.4 0.0 6.5e-60 203.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ADH_zinc_N PF00107.26 ORY09997.1 - 9.7e-14 51.5 0.1 1.9e-13 50.5 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ORY09997.1 - 1.9e-05 24.5 0.0 6.6e-05 22.8 0.0 2.0 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain F-box-like PF12937.7 ORY09998.1 - 0.0005 19.9 0.0 0.002 18.0 0.0 2.1 2 0 0 2 2 2 1 F-box-like Kinesin PF00225.23 ORY09999.1 - 1.2e-47 162.5 0.0 1.7e-28 99.6 0.0 2.1 2 0 0 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 ORY09999.1 - 2e-07 31.1 0.0 3.5e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Microtubule binding MFS_1 PF07690.16 ORY10001.1 - 2.8e-13 49.5 66.6 1.7e-11 43.6 39.0 2.4 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.13 ORY10001.1 - 0.032 12.7 30.3 0.085 11.3 30.3 1.5 1 1 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) AATase PF07247.12 ORY10002.1 - 4e-06 25.7 0.0 0.00018 20.2 0.0 2.6 3 0 0 3 3 3 2 Alcohol acetyltransferase WES_acyltransf PF03007.16 ORY10002.1 - 0.0025 17.6 0.0 0.0036 17.1 0.0 1.2 1 0 0 1 1 1 1 Wax ester synthase-like Acyl-CoA acyltransferase domain Condensation PF00668.20 ORY10002.1 - 0.03 13.0 0.0 0.064 11.9 0.0 1.4 2 0 0 2 2 2 0 Condensation domain Abhydrolase_3 PF07859.13 ORY10003.1 - 1.7e-44 152.2 0.0 2.2e-44 151.9 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 ORY10003.1 - 1.2e-09 37.6 0.0 2.8e-09 36.4 0.0 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.7 ORY10003.1 - 0.0014 19.3 0.4 0.0022 18.6 0.4 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 ORY10003.1 - 0.024 14.2 0.1 0.052 13.1 0.0 1.5 2 0 0 2 2 2 0 Dienelactone hydrolase family Peptidase_S9 PF00326.21 ORY10003.1 - 0.058 12.9 0.0 0.5 9.8 0.0 2.0 2 0 0 2 2 2 0 Prolyl oligopeptidase family PDDEXK_6 PF04720.12 ORY10006.1 - 0.071 13.0 0.0 0.086 12.8 0.0 1.1 1 0 0 1 1 1 0 PDDEXK-like family of unknown function TfoX_C PF04994.13 ORY10008.1 - 0.078 13.1 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 TfoX C-terminal domain HSP70 PF00012.20 ORY10010.1 - 6e-06 24.7 0.0 9.4e-06 24.1 0.0 1.2 1 0 0 1 1 1 1 Hsp70 protein ABC_membrane PF00664.23 ORY10024.1 - 9.1e-40 137.0 15.1 1.2e-39 136.6 15.1 1.0 1 0 0 1 1 1 1 ABC transporter transmembrane region Pex24p PF06398.11 ORY10024.1 - 0.16 10.9 1.5 0.19 10.7 0.1 1.8 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin AcetylCoA_hydro PF02550.15 ORY10025.1 - 2.1e-49 168.2 0.0 3.1e-49 167.7 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.6 ORY10025.1 - 1.4e-42 145.3 0.0 2.4e-42 144.5 0.0 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain Whi5 PF08528.11 ORY10026.1 - 2.3e-12 46.3 0.1 4.7e-12 45.3 0.1 1.5 1 0 0 1 1 1 1 Whi5 like Mog1 PF04603.12 ORY10026.1 - 0.13 12.6 0.1 0.31 11.4 0.1 1.6 1 1 0 1 1 1 0 Ran-interacting Mog1 protein Pyr_redox_2 PF07992.14 ORY10028.1 - 8e-05 22.0 0.0 0.0064 15.8 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Carb_bind PF10645.9 ORY10029.1 - 8e-33 112.4 29.6 1.6e-20 73.1 8.7 2.2 2 0 0 2 2 2 2 Carbohydrate binding WD40_3 PF15911.5 ORY10029.1 - 0.076 13.0 0.0 0.21 11.6 0.0 1.7 1 1 0 1 1 1 0 WD domain, G-beta repeat IGFL PF14653.6 ORY10029.1 - 0.11 12.5 0.6 0.11 12.5 0.6 3.5 1 1 2 3 3 3 0 Insulin growth factor-like family Metallothio_6 PF05522.11 ORY10029.1 - 0.11 13.0 0.9 0.11 13.0 0.9 2.2 2 0 0 2 2 2 0 Metallothionein zf-primase PF09329.11 ORY10029.1 - 9.5 6.1 7.6 8.3 6.3 0.0 2.9 3 0 0 3 3 3 0 Primase zinc finger Palm_thioest PF02089.15 ORY10031.1 - 1.5e-77 260.7 0.0 1.8e-77 260.4 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF915 PF06028.11 ORY10031.1 - 0.00027 20.3 0.1 0.019 14.3 0.0 2.3 2 1 0 2 2 2 2 Alpha/beta hydrolase of unknown function (DUF915) Ribosomal_L1 PF00687.21 ORY10032.1 - 1.5e-58 197.9 4.2 2.3e-58 197.3 4.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family DUF4196 PF13846.6 ORY10032.1 - 0.092 13.0 9.6 0.13 12.4 5.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4196) Strabismus PF06638.11 ORY10032.1 - 0.11 11.1 2.0 0.19 10.3 2.0 1.2 1 0 0 1 1 1 0 Strabismus protein ubiquitin PF00240.23 ORY10034.1 - 8.6e-35 118.3 0.6 9.4e-35 118.2 0.6 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 ORY10034.1 - 5.4e-17 61.4 0.7 6e-17 61.3 0.7 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 ORY10034.1 - 4.1e-06 27.2 0.2 1.7e-05 25.2 0.2 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_5 PF18037.1 ORY10034.1 - 0.0011 19.3 0.0 0.0012 19.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 ORY10034.1 - 0.0013 18.6 0.0 0.0014 18.5 0.0 1.2 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_4 PF18036.1 ORY10034.1 - 0.0014 18.7 0.3 1.4 9.1 0.1 2.0 2 0 0 2 2 2 2 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 ORY10034.1 - 0.0024 17.9 0.1 0.0052 16.9 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 ORY10034.1 - 0.017 15.7 0.1 0.019 15.5 0.1 1.1 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Sde2_N_Ubi PF13019.6 ORY10034.1 - 0.019 14.8 0.0 0.021 14.6 0.0 1.1 1 0 0 1 1 1 0 Silencing defective 2 N-terminal ubiquitin domain HET PF06985.11 ORY10036.1 - 1.6e-13 51.3 0.0 2.4e-13 50.6 0.0 1.3 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) zf-RRN7 PF11781.8 ORY10038.1 - 3.6e-05 23.3 2.6 7.9e-05 22.3 2.6 1.5 1 0 0 1 1 1 1 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 eIF-5a PF01287.20 ORY10039.1 - 6e-29 100.0 1.3 8.4e-29 99.5 1.3 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 ORY10039.1 - 0.011 15.8 0.1 0.022 14.8 0.0 1.6 2 0 0 2 2 2 0 Elongation factor P (EF-P) KOW-like domain Vps52 PF04129.12 ORY10040.1 - 1.2e-124 416.8 0.0 1.6e-124 416.5 0.0 1.0 1 0 0 1 1 1 1 Vps52 / Sac2 family Sec3_C PF09763.9 ORY10040.1 - 0.014 13.8 2.1 0.024 13.1 2.1 1.4 1 1 0 1 1 1 0 Exocyst complex component Sec3 Xrn1_D3 PF18194.1 ORY10040.1 - 0.037 14.1 0.1 0.13 12.4 0.1 2.0 1 0 0 1 1 1 0 Exoribonuclease 1 Domain-3 Exo70 PF03081.15 ORY10040.1 - 0.039 13.0 0.0 0.13 11.2 0.0 1.9 2 0 0 2 2 2 0 Exo70 exocyst complex subunit S6OS1 PF15676.5 ORY10040.1 - 0.095 11.2 0.2 0.14 10.6 0.2 1.3 1 0 0 1 1 1 0 Six6 opposite strand transcript 1 family Solute_trans_a PF03619.16 ORY10042.1 - 1.4e-97 326.3 8.9 1.7e-97 326.1 8.9 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Arm-DNA-bind_2 PF12167.8 ORY10048.1 - 0.019 14.9 0.1 0.085 12.8 0.0 2.0 2 0 0 2 2 2 0 Arm DNA-binding domain FAD_binding_3 PF01494.19 ORY10049.1 - 7.4e-23 81.3 0.0 1.1e-22 80.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Sugar_tr PF00083.24 ORY10050.1 - 7.9e-24 84.3 10.7 9.5e-24 84.1 10.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY10050.1 - 1e-05 24.7 9.5 1.3e-05 24.3 9.5 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily tRNA-synt_2_TM PF16995.5 ORY10050.1 - 0.02 14.6 0.2 0.035 13.8 0.1 1.5 1 1 0 1 1 1 0 Transmembrane region of lysyl-tRNA synthetase BCDHK_Adom3 PF10436.9 ORY10052.1 - 2e-45 154.6 0.1 3.1e-45 153.9 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 ORY10052.1 - 1.2e-09 38.6 0.2 2.1e-07 31.5 0.2 3.1 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ABC_tran PF00005.27 ORY10053.1 - 4.7e-47 159.9 0.1 1.5e-23 83.9 0.0 3.5 2 1 0 2 2 2 2 ABC transporter 4HB PF17947.1 ORY10053.1 - 5.4e-27 93.7 0.2 2.3e-26 91.6 0.0 2.2 2 0 0 2 2 1 1 Four helical bundle domain AAA_21 PF13304.6 ORY10053.1 - 4.5e-17 62.8 0.3 0.0026 17.6 0.1 5.1 4 1 0 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ORY10053.1 - 5.5e-16 58.7 0.1 1.1e-06 28.3 0.0 3.5 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 ORY10053.1 - 4.7e-08 32.7 0.1 0.0097 15.6 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 ORY10053.1 - 1.3e-07 32.3 0.8 8.8e-05 23.1 0.0 3.2 4 1 0 4 4 2 2 AAA domain AAA_28 PF13521.6 ORY10053.1 - 1.8e-07 31.5 0.1 0.022 15.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 ORY10053.1 - 7.3e-07 29.5 0.0 0.019 15.2 0.0 3.5 4 0 0 4 4 2 2 AAA domain RsgA_GTPase PF03193.16 ORY10053.1 - 1.3e-06 28.4 0.3 0.0017 18.3 0.0 2.9 3 0 0 3 3 2 1 RsgA GTPase MMR_HSR1 PF01926.23 ORY10053.1 - 3.8e-06 27.0 0.0 0.0038 17.3 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 ORY10053.1 - 4e-06 26.6 0.1 0.12 12.1 0.0 3.1 3 0 0 3 3 2 2 Ethanolamine utilisation - propanediol utilisation AAA PF00004.29 ORY10053.1 - 5.1e-06 26.9 0.0 0.12 12.8 0.1 4.1 4 1 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 ORY10053.1 - 6.6e-06 26.6 0.4 0.16 12.3 0.0 3.8 4 1 0 4 4 3 2 AAA ATPase domain AAA_33 PF13671.6 ORY10053.1 - 1e-05 25.8 0.0 0.14 12.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 ORY10053.1 - 2.7e-05 24.7 0.1 0.45 11.1 0.0 3.1 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 ORY10053.1 - 0.00012 22.0 0.0 0.086 12.8 0.0 2.7 2 0 0 2 2 2 1 NACHT domain DUF87 PF01935.17 ORY10053.1 - 0.00013 22.2 1.0 0.21 11.7 0.0 3.7 3 0 0 3 3 3 1 Helicase HerA, central domain RNA_helicase PF00910.22 ORY10053.1 - 0.00015 22.1 0.0 0.86 10.0 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA_15 PF13175.6 ORY10053.1 - 0.00022 21.1 0.4 0.99 9.0 0.0 3.3 3 1 0 3 3 2 2 AAA ATPase domain Dynamin_N PF00350.23 ORY10053.1 - 0.00024 21.2 0.1 0.002 18.2 0.0 2.5 2 1 0 2 2 2 1 Dynamin family AAA_14 PF13173.6 ORY10053.1 - 0.00036 20.6 0.4 0.44 10.6 0.0 3.3 4 0 0 4 4 2 1 AAA domain MeaB PF03308.16 ORY10053.1 - 0.00038 19.5 0.1 0.16 10.9 0.0 2.4 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_24 PF13479.6 ORY10053.1 - 0.00049 19.9 0.0 1.3 8.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_13 PF13166.6 ORY10053.1 - 0.00051 18.8 2.7 0.53 8.9 0.0 4.0 4 0 0 4 4 4 1 AAA domain G-alpha PF00503.20 ORY10053.1 - 0.00058 19.1 0.1 0.94 8.6 0.0 2.6 2 0 0 2 2 2 2 G-protein alpha subunit SbcCD_C PF13558.6 ORY10053.1 - 0.0011 19.1 0.0 1.2 9.4 0.0 3.2 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit cobW PF02492.19 ORY10053.1 - 0.0012 18.4 0.0 0.83 9.2 0.0 3.1 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 ORY10053.1 - 0.0012 18.6 0.0 1 9.0 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_27 PF13514.6 ORY10053.1 - 0.0016 18.1 0.1 1 8.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain Roc PF08477.13 ORY10053.1 - 0.0023 18.1 0.0 2.2 8.5 0.0 2.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase HEAT_2 PF13646.6 ORY10053.1 - 0.0036 17.7 0.3 6.7 7.2 0.2 3.1 2 1 1 3 3 2 0 HEAT repeats NB-ARC PF00931.22 ORY10053.1 - 0.0046 16.2 2.0 0.083 12.1 0.0 2.7 3 0 0 3 3 2 1 NB-ARC domain HEAT PF02985.22 ORY10053.1 - 0.0054 16.9 0.2 4.8 7.7 0.0 3.6 3 0 0 3 3 2 0 HEAT repeat ATP_bind_1 PF03029.17 ORY10053.1 - 0.0061 16.4 0.0 4.1 7.1 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein ATPase_2 PF01637.18 ORY10053.1 - 0.0093 15.9 0.0 1.2 9.0 0.0 3.0 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea ATP-synt_ab PF00006.25 ORY10053.1 - 0.011 15.4 0.0 2.6 7.6 0.0 2.5 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Rad17 PF03215.15 ORY10053.1 - 0.012 15.5 0.0 0.88 9.5 0.0 2.6 2 0 0 2 2 2 0 Rad17 P-loop domain CLP1_P PF16575.5 ORY10053.1 - 0.016 15.0 0.1 1.5 8.6 0.0 2.7 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_7 PF12775.7 ORY10053.1 - 0.017 14.7 0.0 2.3 7.7 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region TsaE PF02367.17 ORY10053.1 - 0.027 14.5 0.0 7.5 6.6 0.0 2.9 2 1 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 ORY10053.1 - 0.027 13.8 0.0 4.1 6.7 0.0 3.0 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI Septin PF00735.18 ORY10053.1 - 0.029 13.6 0.2 4.2 6.5 0.0 2.8 3 0 0 3 3 3 0 Septin DRIM PF07539.12 ORY10053.1 - 0.035 12.4 1.3 3.4 5.9 0.3 2.2 2 0 0 2 2 2 0 Down-regulated in metastasis IstB_IS21 PF01695.17 ORY10053.1 - 0.037 13.8 0.0 8.7 6.0 0.0 2.8 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_5 PF07728.14 ORY10053.1 - 0.037 14.0 0.0 12 5.9 0.0 3.2 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) T2SSE PF00437.20 ORY10053.1 - 0.039 13.0 0.1 6 5.8 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_25 PF13481.6 ORY10053.1 - 0.04 13.5 0.0 6.1 6.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain dNK PF01712.19 ORY10053.1 - 0.058 13.3 0.0 1.7 8.4 0.0 2.5 2 0 0 2 2 2 0 Deoxynucleoside kinase PRK PF00485.18 ORY10053.1 - 0.066 12.9 0.1 5.2 6.8 0.0 2.8 3 0 0 3 3 3 0 Phosphoribulokinase / Uridine kinase family NTPase_1 PF03266.15 ORY10053.1 - 0.066 13.1 0.4 13 5.7 0.1 2.8 2 1 0 2 2 2 0 NTPase ParcG PF10274.9 ORY10053.1 - 0.073 13.2 0.6 7.5 6.6 0.0 3.1 2 1 1 3 3 3 0 Parkin co-regulated protein Transglut_prok PF09017.10 ORY10053.1 - 0.074 12.4 1.0 0.13 11.6 0.2 1.7 2 0 0 2 2 2 0 Microbial transglutaminase Arf PF00025.21 ORY10053.1 - 0.096 12.1 0.0 18 4.7 0.0 2.5 2 0 0 2 2 2 0 ADP-ribosylation factor family MukB PF04310.12 ORY10053.1 - 0.15 11.9 0.1 21 4.9 0.0 2.5 2 0 0 2 2 2 0 MukB N-terminal RuvB_N PF05496.12 ORY10053.1 - 0.15 11.8 0.1 19 5.0 0.0 2.8 3 0 0 3 3 2 0 Holliday junction DNA helicase RuvB P-loop domain FeoB_N PF02421.18 ORY10053.1 - 0.16 11.4 0.2 2.1 7.8 0.1 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B Acetyltransf_1 PF00583.25 ORY10054.1 - 2.4e-13 50.4 0.0 2.8e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ORY10054.1 - 8.2e-11 41.9 0.0 1e-10 41.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ORY10054.1 - 1.4e-09 38.2 0.0 2e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ORY10054.1 - 2.8e-05 24.0 0.0 4e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 ORY10054.1 - 0.0087 16.2 0.0 0.012 15.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 ORY10054.1 - 0.038 14.1 0.0 0.065 13.4 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase SNF2_N PF00176.23 ORY10055.1 - 1.2e-63 215.0 0.0 3.3e-63 213.5 0.0 1.7 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ORY10055.1 - 8.3e-20 71.2 0.0 6.5e-19 68.3 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY10055.1 - 1.2e-10 41.6 0.1 3.4e-09 36.9 0.0 2.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 ORY10055.1 - 2.2e-06 27.0 0.8 9.7e-05 21.7 0.0 2.9 3 0 0 3 3 3 1 Class II histone deacetylase complex subunits 2 and 3 LEM PF03020.15 ORY10056.1 - 0.065 12.8 0.0 0.26 10.9 0.0 2.1 1 0 0 1 1 1 0 LEM domain Chitin_bind_1 PF00187.19 ORY10057.1 - 2.3e-20 72.8 80.0 3.9e-10 40.0 16.4 4.6 3 2 1 4 4 4 3 Chitin recognition protein CCDC53 PF10152.9 ORY10057.1 - 0.094 13.1 0.4 8.5 6.8 0.0 2.2 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex HSP70 PF00012.20 ORY10058.1 - 8.9e-164 546.0 4.5 3.9e-163 543.8 3.1 2.1 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 ORY10058.1 - 4.8e-14 51.9 0.0 2.5e-11 43.0 0.0 2.3 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 ORY10058.1 - 0.057 13.9 0.1 15 6.1 0.0 2.9 2 0 0 2 2 2 0 Cell division protein FtsA YonK PF09642.10 ORY10058.1 - 0.069 13.3 0.0 0.94 9.7 0.0 2.7 2 0 0 2 2 2 0 YonK protein BcrAD_BadFG PF01869.20 ORY10058.1 - 0.13 11.7 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family DNA_pol3_a_NII PF11490.8 ORY10058.1 - 2.3 8.1 9.9 35 4.3 5.7 3.2 2 0 0 2 2 2 0 DNA polymerase III polC-type N-terminus II CENP-L PF13092.6 ORY10059.1 - 1.7e-42 145.4 1.4 2.3e-42 145.0 1.4 1.2 1 0 0 1 1 1 1 Kinetochore complex Sim4 subunit Fta1 TetR_C_24 PF17932.1 ORY10060.1 - 0.0013 18.9 0.1 0.0016 18.7 0.1 1.1 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain Tmemb_cc2 PF10267.9 ORY10060.1 - 0.65 9.1 1.9 0.74 8.9 1.9 1.0 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Mitochondr_Som1 PF11093.8 ORY10063.1 - 4.6e-11 42.5 0.0 8.9e-11 41.6 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial export protein Som1 TAF8_C PF10406.9 ORY10064.1 - 3.1e-18 66.0 0.3 3.1e-18 66.0 0.3 1.9 2 0 0 2 2 2 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP PF07524.13 ORY10064.1 - 0.0028 17.6 0.0 0.0042 17.1 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated Adap_comp_sub PF00928.21 ORY10066.1 - 2.2e-53 181.4 0.0 2.8e-53 181.0 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 ORY10066.1 - 0.021 14.8 0.0 0.048 13.6 0.0 1.5 2 0 0 2 2 2 0 Clathrin adaptor complex small chain DUF4536 PF15055.6 ORY10067.1 - 2.5e-08 34.0 5.2 4.4e-07 30.0 3.9 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF4536) DUF4588 PF15251.6 ORY10068.1 - 2.2e-06 27.6 4.2 6.4e-06 26.1 4.2 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4588) IBR PF01485.21 ORY10069.1 - 1.5e-07 31.5 23.1 8.3e-06 25.9 3.2 3.2 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain TAXi_N PF14543.6 ORY10069.1 - 0.027 14.7 5.2 0.027 14.7 5.2 1.9 1 1 1 2 2 2 0 Xylanase inhibitor N-terminal Cu-oxidase_3 PF07732.15 ORY10070.1 - 3.5e-34 117.4 5.4 1.2e-33 115.6 0.2 3.0 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.22 ORY10070.1 - 5.8e-34 117.5 0.0 6.6e-29 101.1 0.0 2.5 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 ORY10070.1 - 7.2e-29 100.3 7.0 3.8e-27 94.7 2.4 3.3 3 1 0 3 3 3 2 Multicopper oxidase HET PF06985.11 ORY10071.1 - 1.6e-23 83.7 0.0 4.6e-23 82.2 0.0 1.8 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) adh_short PF00106.25 ORY10072.1 - 2.2e-23 82.8 0.0 9e-18 64.4 0.0 2.1 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 ORY10072.1 - 2.1e-21 76.5 0.0 1.8e-18 67.0 0.0 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY10073.1 - 3.8e-21 75.5 0.5 4.2e-19 68.8 0.9 2.1 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 ORY10073.1 - 6.6e-12 45.7 1.4 1.2e-11 44.8 1.4 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 ORY10073.1 - 3.4e-09 36.6 1.2 3.1e-08 33.4 0.9 2.0 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Ldh_1_N PF00056.23 ORY10073.1 - 0.033 14.3 0.2 0.053 13.6 0.2 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain GMC_oxred_C PF05199.13 ORY10074.1 - 6.6e-12 46.2 0.2 4.4e-11 43.5 0.2 2.2 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 ORY10074.1 - 0.00016 21.1 0.3 0.02 14.3 0.5 3.2 2 1 2 4 4 4 2 GMC oxidoreductase AltA1 PF16541.5 ORY10075.1 - 5.3e-12 46.6 0.6 7e-12 46.2 0.6 1.2 1 0 0 1 1 1 1 Alternaria alternata allergen 1 AA_permease PF00324.21 ORY10076.1 - 8.2e-30 103.8 28.2 4.8e-15 55.1 5.7 3.8 1 1 1 3 3 3 3 Amino acid permease AA_permease_2 PF13520.6 ORY10076.1 - 5.3e-05 22.2 17.9 0.00067 18.6 5.5 2.2 2 0 0 2 2 2 2 Amino acid permease KleE PF17394.2 ORY10076.1 - 0.79 10.0 3.6 0.22 11.8 0.5 1.6 2 0 0 2 2 2 0 Uncharacterized KleE stable inheritance protein TAD2 PF18521.1 ORY10077.1 - 0.012 15.5 0.8 0.038 13.9 0.8 1.8 1 0 0 1 1 1 0 Transactivation domain 2 Zn_clus PF00172.18 ORY10080.1 - 5.1e-09 36.1 11.5 9.2e-09 35.3 11.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Nucleotid_trans PF03407.16 ORY10082.1 - 2.9e-07 30.7 0.3 1.1e-06 28.8 0.2 2.0 2 0 0 2 2 2 1 Nucleotide-diphospho-sugar transferase Glyco_transf_34 PF05637.12 ORY10082.1 - 7.4e-05 22.6 3.7 0.00017 21.4 3.7 1.7 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family DUF2947 PF11163.8 ORY10082.1 - 0.05 13.4 0.1 0.11 12.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2947) IBR PF01485.21 ORY10098.1 - 1.5e-13 50.7 51.8 8.3e-10 38.7 3.3 5.3 4 1 0 4 4 4 3 IBR domain, a half RING-finger domain 2OG-FeII_Oxy_3 PF13640.6 ORY10099.1 - 0.075 13.9 0.0 1.4 9.8 0.0 2.4 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily DUF1624 PF07786.12 ORY10100.1 - 0.038 13.6 2.5 0.045 13.3 1.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1624) zf-C3HC4 PF00097.25 ORY10101.1 - 1.9e-05 24.4 2.3 4.1e-05 23.3 2.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORY10101.1 - 2.5e-05 24.5 3.4 6.1e-05 23.3 3.4 1.7 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 ORY10101.1 - 5.8e-05 22.9 0.8 0.00012 21.8 0.8 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 ORY10101.1 - 0.0023 17.7 0.9 0.0054 16.6 0.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 ORY10101.1 - 0.0098 16.2 1.6 0.025 14.9 1.6 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 ORY10101.1 - 0.012 15.6 2.0 0.03 14.3 2.0 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.6 ORY10101.1 - 0.034 14.1 3.8 0.15 12.0 4.0 1.9 1 1 0 1 1 1 0 zinc-RING finger domain zf-ANAPC11 PF12861.7 ORY10101.1 - 0.042 13.9 0.1 0.13 12.4 0.1 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 ORY10101.1 - 0.063 13.5 1.9 0.14 12.3 1.9 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 ORY10101.1 - 0.086 12.7 5.6 0.32 10.9 5.6 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) IBR PF01485.21 ORY10101.1 - 3.3 8.0 7.2 0.27 11.5 0.6 2.5 2 1 1 3 3 3 0 IBR domain, a half RING-finger domain Zn_Tnp_IS91 PF14319.6 ORY10103.1 - 0.013 15.5 4.8 0.029 14.4 4.8 1.5 1 0 0 1 1 1 0 Transposase zinc-binding domain FAD_binding_3 PF01494.19 ORY10104.1 - 3.9e-37 128.3 0.0 5.5e-37 127.8 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 ORY10104.1 - 0.00023 21.3 0.0 0.00052 20.2 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ORY10104.1 - 0.00039 19.7 0.0 0.00098 18.4 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ORY10104.1 - 0.0013 18.4 0.0 0.66 9.5 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.14 ORY10104.1 - 0.0021 16.8 0.2 0.031 13.0 0.1 2.0 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 ORY10104.1 - 0.0022 18.5 0.0 1.1 9.8 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 ORY10104.1 - 0.005 16.1 0.0 0.0082 15.4 0.0 1.2 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 ORY10104.1 - 0.016 14.3 0.2 0.059 12.4 0.2 1.8 1 1 0 1 1 1 0 Lycopene cyclase protein FAD_binding_2 PF00890.24 ORY10104.1 - 0.047 12.8 0.0 0.2 10.7 0.0 1.9 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_3 PF13738.6 ORY10104.1 - 0.19 10.9 0.1 0.63 9.2 0.1 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ORY10104.1 - 1.6 8.7 3.4 7.7 6.5 0.1 3.2 3 1 1 4 4 4 0 FAD-NAD(P)-binding ThrE PF06738.12 ORY10105.1 - 2.1e-69 233.6 13.7 9.6e-67 224.9 2.0 3.1 3 1 1 4 4 4 2 Putative threonine/serine exporter ThrE_2 PF12821.7 ORY10105.1 - 2.5e-05 24.4 1.5 2.5e-05 24.4 1.5 3.7 4 0 0 4 4 4 3 Threonine/Serine exporter, ThrE CVNH PF08881.10 ORY10107.1 - 1.9e-11 44.6 0.2 3e-11 43.9 0.2 1.3 1 0 0 1 1 1 1 CVNH domain Sh_2 PF17512.2 ORY10108.1 - 0.067 13.0 0.1 0.072 12.9 0.1 1.1 1 0 0 1 1 1 0 Metapneumovirus Small hydrophobic protein DUF3328 PF11807.8 ORY10109.1 - 0.048 13.4 0.1 0.14 11.9 0.0 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF3328) DUF3328 PF11807.8 ORY10110.1 - 2.2e-21 76.6 0.7 2.5e-21 76.5 0.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) AA_permease_2 PF13520.6 ORY10112.1 - 2.4e-39 135.4 30.9 4.1e-39 134.6 30.9 1.3 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ORY10112.1 - 6.8e-13 48.0 33.1 1.5e-12 46.9 33.1 1.6 1 1 0 1 1 1 1 Amino acid permease Epiglycanin_C PF14654.6 ORY10112.1 - 0.025 14.6 0.1 0.025 14.6 0.1 2.3 3 0 0 3 3 3 0 Mucin, catalytic, TM and cytoplasmic tail region DUF2633 PF11119.8 ORY10112.1 - 0.035 14.0 0.3 0.11 12.4 0.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) BNR_2 PF13088.6 ORY10113.1 - 0.014 14.7 2.1 0.13 11.5 0.1 2.3 2 1 0 2 2 2 0 BNR repeat-like domain Esterase_phd PF10503.9 ORY10114.1 - 1.4e-25 90.1 1.8 2.2e-25 89.5 1.8 1.2 1 0 0 1 1 1 1 Esterase PHB depolymerase CBM_1 PF00734.18 ORY10114.1 - 8.7e-12 44.8 10.5 8.7e-12 44.8 10.5 2.4 2 0 0 2 2 2 1 Fungal cellulose binding domain Peptidase_S9 PF00326.21 ORY10114.1 - 1.7e-09 37.5 1.3 3.7e-09 36.4 1.0 1.6 1 1 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 ORY10114.1 - 0.00014 21.6 1.0 0.0002 21.1 1.0 1.2 1 0 0 1 1 1 1 Putative esterase COesterase PF00135.28 ORY10114.1 - 0.01 14.7 0.9 0.017 14.0 0.9 1.3 1 0 0 1 1 1 0 Carboxylesterase family Abhydrolase_3 PF07859.13 ORY10114.1 - 0.013 15.4 0.1 0.02 14.7 0.1 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 ORY10114.1 - 0.016 14.8 3.2 0.028 14.0 3.2 1.5 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) BAAT_C PF08840.11 ORY10114.1 - 0.029 14.3 0.2 0.054 13.4 0.2 1.5 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Hydrolase_4 PF12146.8 ORY10114.1 - 0.18 11.1 0.0 0.52 9.5 0.1 1.6 2 0 0 2 2 2 0 Serine aminopeptidase, S33 DLH PF01738.18 ORY10114.1 - 0.27 10.8 2.4 2.2 7.8 2.4 2.1 1 1 0 1 1 1 0 Dienelactone hydrolase family Tannase PF07519.11 ORY10115.1 - 1.6e-92 310.9 0.0 1.8e-92 310.7 0.0 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_S9 PF00326.21 ORY10115.1 - 0.00035 20.1 0.0 0.039 13.4 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 ORY10115.1 - 0.0072 16.0 0.0 0.52 9.9 0.0 2.3 2 0 0 2 2 2 1 alpha/beta hydrolase fold Esterase PF00756.20 ORY10115.1 - 0.082 12.5 0.2 0.13 11.9 0.2 1.2 1 0 0 1 1 1 0 Putative esterase Hydrolase_4 PF12146.8 ORY10115.1 - 0.17 11.1 0.0 0.53 9.5 0.0 1.7 2 0 0 2 2 2 0 Serine aminopeptidase, S33 DNA_pol_A_exo1 PF01612.20 ORY10116.1 - 0.0019 18.0 0.0 0.0043 16.8 0.0 1.6 2 0 0 2 2 2 1 3'-5' exonuclease Zn_dep_PLPC PF00882.18 ORY10116.1 - 0.12 12.3 0.5 0.24 11.4 0.1 1.7 2 0 0 2 2 2 0 Zinc dependent phospholipase C RNA_POL_M_15KD PF02150.16 ORY10116.1 - 0.24 11.3 1.6 0.56 10.1 1.6 1.6 1 0 0 1 1 1 0 RNA polymerases M/15 Kd subunit TPPK_C PF12555.8 ORY10117.1 - 0.4 10.8 3.6 0.7 10.0 0.2 2.3 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal DIOX_N PF14226.6 ORY10118.1 - 2.5e-14 54.0 0.1 9.5e-11 42.5 0.1 2.3 1 1 1 2 2 2 2 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 ORY10118.1 - 0.00079 19.9 0.0 0.67 10.5 0.0 2.4 1 1 1 2 2 2 2 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.16 ORY10119.1 - 1.5e-25 89.8 30.2 2.2e-25 89.4 30.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 ORY10119.1 - 2.9e-05 23.5 14.3 8.9e-05 21.9 10.3 2.2 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB AAA_22 PF13401.6 ORY10120.1 - 1e-09 38.8 0.0 3.5e-09 37.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ORY10120.1 - 5.5e-07 30.1 0.1 1.6e-06 28.6 0.1 1.8 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 ORY10120.1 - 1.8e-06 28.0 0.2 8.3e-06 25.8 0.1 2.2 2 0 0 2 2 2 1 NACHT domain AAA PF00004.29 ORY10120.1 - 0.00047 20.6 0.0 0.0021 18.5 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TPR_12 PF13424.6 ORY10120.1 - 0.0029 17.9 3.5 1.6 9.1 0.5 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 ORY10120.1 - 0.0051 16.8 8.9 4.6 7.6 0.2 5.0 4 0 0 4 4 4 1 Tetratricopeptide repeat NB-ARC PF00931.22 ORY10120.1 - 0.014 14.5 0.0 0.037 13.2 0.0 1.7 1 0 0 1 1 1 0 NB-ARC domain ATPase_2 PF01637.18 ORY10120.1 - 0.033 14.1 0.0 0.063 13.2 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea TPR_6 PF13174.6 ORY10120.1 - 0.036 14.7 1.1 23 5.9 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat RNA_helicase PF00910.22 ORY10120.1 - 0.11 12.8 0.0 0.75 10.2 0.0 2.4 2 0 0 2 2 2 0 RNA helicase ABC_tran PF00005.27 ORY10120.1 - 0.12 12.8 0.0 0.38 11.3 0.0 1.9 1 0 0 1 1 1 0 ABC transporter AAA_10 PF12846.7 ORY10120.1 - 0.18 10.7 0.0 0.33 9.8 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain RF-1 PF00472.20 ORY10120.1 - 0.19 11.7 0.3 0.46 10.4 0.3 1.6 1 0 0 1 1 1 0 RF-1 domain MBOAT_2 PF13813.6 ORY10122.1 - 8.1e-20 70.9 4.8 2.4e-19 69.4 4.8 1.9 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family DUF1100 PF06500.11 ORY10123.1 - 3.2e-08 32.8 0.0 5.7e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Peptidase_S15 PF02129.18 ORY10123.1 - 2.8e-05 23.9 0.0 5.5e-05 22.9 0.0 1.5 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 ORY10123.1 - 0.00022 20.7 0.0 0.00098 18.7 0.0 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 ORY10123.1 - 0.0007 19.3 0.0 0.0063 16.2 0.0 2.1 1 1 0 1 1 1 1 Putative esterase BAAT_C PF08840.11 ORY10123.1 - 0.0013 18.7 0.0 0.0021 18.0 0.0 1.3 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_1 PF00561.20 ORY10123.1 - 0.029 14.0 0.0 0.08 12.6 0.0 1.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold DLH PF01738.18 ORY10123.1 - 0.029 13.9 0.0 0.18 11.3 0.0 2.0 1 1 0 1 1 1 0 Dienelactone hydrolase family Hydrolase_4 PF12146.8 ORY10123.1 - 0.058 12.7 0.0 0.13 11.5 0.0 1.6 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ORY10123.1 - 0.058 14.0 0.1 0.09 13.4 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF2811 PF10929.8 ORY10123.1 - 0.16 12.3 0.0 0.34 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2811) zf-CCCH_8 PF18633.1 ORY10125.1 - 0.065 13.4 0.2 0.1 12.7 0.2 1.2 1 0 0 1 1 1 0 Zinc-finger antiviral protein (ZAP) zinc finger domain 3 HisKA_3 PF07730.13 ORY10126.1 - 0.0045 17.5 0.2 0.026 15.0 0.1 2.2 2 0 0 2 2 2 1 Histidine kinase Peptidase_C2 PF00648.21 ORY10128.1 - 1.1e-65 221.6 0.5 1.3e-43 149.1 0.1 2.2 2 0 0 2 2 2 2 Calpain family cysteine protease AvrLm4-7 PF18661.1 ORY10128.1 - 0.077 14.0 0.3 0.25 12.4 0.3 1.8 1 0 0 1 1 1 0 Avirulence Effector AvrLm4-7 AAA_23 PF13476.6 ORY10128.1 - 0.48 10.9 5.7 0.95 9.9 5.7 1.5 1 0 0 1 1 1 0 AAA domain TPR_10 PF13374.6 ORY10129.1 - 3.9e-35 118.7 1.5 3.2e-11 42.7 0.0 4.2 4 1 0 4 4 4 4 Tetratricopeptide repeat TPR_12 PF13424.6 ORY10129.1 - 3.2e-32 110.6 4.2 8.2e-16 58.1 0.0 3.1 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.6 ORY10129.1 - 2.9e-10 39.4 1.0 0.00031 20.5 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 ORY10129.1 - 3.7e-05 23.4 0.3 0.035 13.9 0.0 3.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_4 PF07721.14 ORY10129.1 - 0.00062 20.1 0.6 1.3 9.8 0.2 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 ORY10129.1 - 0.0054 17.3 0.0 4.6 8.0 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 ORY10129.1 - 0.021 14.9 1.7 3.3 8.1 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF1925 PF09094.11 ORY10129.1 - 0.025 14.9 0.1 10 6.5 0.0 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF1925) TPR_17 PF13431.6 ORY10129.1 - 0.038 14.4 0.3 1.1 9.8 0.0 3.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 ORY10129.1 - 0.088 13.1 0.3 8.8 6.8 0.1 3.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 ORY10129.1 - 0.1 13.5 0.8 6.5 7.9 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 ORY10129.1 - 0.11 13.0 0.2 2.1 8.9 0.0 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat Patatin PF01734.22 ORY10130.1 - 2.2e-22 80.3 0.0 5.4e-22 79.0 0.0 1.7 1 0 0 1 1 1 1 Patatin-like phospholipase AAA_22 PF13401.6 ORY10130.1 - 0.00032 21.0 0.1 0.0013 19.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 ORY10130.1 - 0.00068 18.9 0.0 0.0011 18.2 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain SAM_KSR1 PF13543.6 ORY10130.1 - 0.0007 19.7 0.4 0.12 12.6 0.0 2.5 2 0 0 2 2 2 1 SAM like domain present in kinase suppressor RAS 1 AAA_16 PF13191.6 ORY10130.1 - 0.013 15.9 0.0 0.034 14.5 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 ORY10130.1 - 0.028 14.0 0.0 0.14 11.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain ResIII PF04851.15 ORY10130.1 - 0.047 13.7 0.0 0.13 12.2 0.0 1.8 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit ArsA_ATPase PF02374.15 ORY10130.1 - 0.089 12.0 0.0 0.43 9.7 0.0 2.0 2 0 0 2 2 2 0 Anion-transporting ATPase Peptidase_S8 PF00082.22 ORY10131.1 - 2.8e-22 79.3 0.1 7.2e-22 78.0 0.1 1.5 1 1 0 1 1 1 1 Subtilase family SesA PF17107.5 ORY10133.1 - 0.024 14.8 0.1 0.06 13.5 0.1 1.6 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases TAP42 PF04177.12 ORY10133.1 - 0.052 12.7 0.1 0.068 12.3 0.1 1.2 1 0 0 1 1 1 0 TAP42-like family PNP_UDP_1 PF01048.20 ORY10134.1 - 3.3e-07 29.8 0.0 3.5e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily HlyIII PF03006.20 ORY10135.1 - 5.4e-47 160.4 18.5 6.6e-47 160.1 18.5 1.1 1 0 0 1 1 1 1 Haemolysin-III related NAD_binding_10 PF13460.6 ORY10136.1 - 5.2e-08 33.0 0.0 8.6e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 ORY10136.1 - 1.6e-05 24.6 0.0 3.5e-05 23.5 0.0 1.4 2 0 0 2 2 2 1 NmrA-like family 3Beta_HSD PF01073.19 ORY10136.1 - 0.0033 16.5 0.0 0.0045 16.0 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 ORY10136.1 - 0.004 16.3 0.0 0.0054 15.9 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein KR PF08659.10 ORY10136.1 - 0.016 15.1 0.1 0.023 14.6 0.1 1.3 1 0 0 1 1 1 0 KR domain Semialdhyde_dh PF01118.24 ORY10136.1 - 0.073 13.5 0.0 0.14 12.6 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.21 ORY10136.1 - 0.11 12.0 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family TPR_12 PF13424.6 ORY10137.1 - 3.7e-22 78.4 0.0 9e-12 45.1 0.0 2.0 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 ORY10137.1 - 3.1e-21 74.6 0.0 4.9e-11 42.1 0.0 2.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 ORY10137.1 - 6.4e-08 32.1 0.0 0.0078 16.2 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 ORY10137.1 - 0.00011 22.0 0.0 0.52 10.6 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_4 PF07721.14 ORY10137.1 - 0.00017 21.9 0.0 0.083 13.6 0.0 2.5 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 ORY10137.1 - 0.0072 16.8 0.0 0.12 13.0 0.0 2.0 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 ORY10137.1 - 0.019 15.7 0.0 5.6 8.1 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat PPR PF01535.20 ORY10137.1 - 0.02 15.1 0.1 1.8 9.0 0.1 2.6 2 0 0 2 2 2 0 PPR repeat TPR_1 PF00515.28 ORY10137.1 - 0.025 14.4 0.0 11 6.1 0.0 2.6 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 ORY10137.1 - 0.031 14.9 0.0 2.8 8.7 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_MalT PF17874.1 ORY10137.1 - 0.079 12.3 0.0 0.089 12.1 0.0 1.1 1 0 0 1 1 1 0 MalT-like TPR region BTAD PF03704.17 ORY10137.1 - 0.12 12.8 0.0 0.42 11.0 0.0 1.8 1 1 1 2 2 2 0 Bacterial transcriptional activator domain CRR7 PF12095.8 ORY10139.1 - 0.0011 19.3 4.5 0.4 11.2 1.0 3.6 1 1 2 3 3 3 2 Protein CHLORORESPIRATORY REDUCTION 7 DUF2452 PF10504.9 ORY10139.1 - 0.35 10.3 3.3 0.14 11.7 0.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2452) p450 PF00067.22 ORY10141.1 - 2.2e-21 76.1 0.1 2.5e-18 66.1 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 Glyco_hydro_61 PF03443.14 ORY10142.1 - 1.1e-51 175.7 0.4 1.3e-51 175.4 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Methyltransf_25 PF13649.6 ORY10153.1 - 4.9e-16 59.2 0.0 8.3e-16 58.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY10153.1 - 1.4e-15 57.6 0.0 1.8e-15 57.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY10153.1 - 4e-13 49.8 0.0 7.3e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY10153.1 - 2.4e-08 33.9 0.0 3.3e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY10153.1 - 6.7e-08 33.2 0.0 9.9e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain TPMT PF05724.11 ORY10153.1 - 5e-07 29.6 0.0 1.5e-06 28.1 0.0 1.7 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) CMAS PF02353.20 ORY10153.1 - 3.5e-05 23.2 0.0 4.5e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.13 ORY10153.1 - 0.0035 16.8 0.0 0.005 16.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.19 ORY10153.1 - 0.0053 16.5 0.0 0.0076 16.0 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CheR PF01739.18 ORY10153.1 - 0.009 15.5 0.1 1.5 8.2 0.0 2.2 1 1 1 2 2 2 2 CheR methyltransferase, SAM binding domain MTS PF05175.14 ORY10153.1 - 0.011 15.3 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_32 PF13679.6 ORY10153.1 - 0.012 15.7 0.0 0.017 15.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 ORY10153.1 - 0.067 12.5 0.0 0.25 10.7 0.0 1.9 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family UDPG_MGDP_dh_N PF03721.14 ORY10153.1 - 0.16 11.5 0.0 0.25 10.9 0.0 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DNA_pol_E_B PF04042.16 ORY10154.1 - 4.1e-46 157.0 0.0 5.9e-46 156.5 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B SHNi-TPR PF10516.9 ORY10155.1 - 6.1e-14 51.2 2.1 2.3e-13 49.3 0.3 2.5 2 0 0 2 2 2 1 SHNi-TPR TPR_10 PF13374.6 ORY10155.1 - 3.6e-05 23.5 6.6 0.27 11.2 0.1 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 ORY10155.1 - 4.5e-05 23.6 16.5 0.0021 18.3 2.1 3.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 ORY10155.1 - 0.00076 19.7 0.0 2.1 8.9 0.0 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 ORY10155.1 - 0.0015 18.2 1.3 0.45 10.4 0.6 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_3 PF07720.12 ORY10155.1 - 0.019 14.9 0.8 0.019 14.9 0.8 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat GPW_gp25 PF04965.14 ORY10155.1 - 0.18 11.6 1.4 0.43 10.4 1.4 1.6 1 0 0 1 1 1 0 Gene 25-like lysozyme DUF1690 PF07956.11 ORY10155.1 - 0.69 10.3 8.4 0.67 10.4 3.4 2.8 2 0 0 2 2 2 0 Protein of Unknown function (DUF1690) TPR_2 PF07719.17 ORY10155.1 - 0.97 9.7 17.1 1.6 9.0 0.3 5.0 6 0 0 6 6 6 0 Tetratricopeptide repeat TMPIT PF07851.13 ORY10155.1 - 2.5 7.3 4.7 5.1 6.2 4.7 1.5 1 0 0 1 1 1 0 TMPIT-like protein TPR_8 PF13181.6 ORY10155.1 - 5 7.6 7.5 15 6.1 0.3 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Abhydrolase_3 PF07859.13 ORY10156.1 - 7.5e-08 32.5 0.1 8.5e-08 32.3 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 ORY10156.1 - 4.1e-07 29.3 0.0 4.8e-07 29.0 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family PARP_reg PF02877.14 ORY10157.1 - 0.021 14.9 0.0 0.034 14.2 0.0 1.3 1 0 0 1 1 1 0 Poly(ADP-ribose) polymerase, regulatory domain BCS1_N PF08740.11 ORY10158.1 - 4.3e-06 26.8 0.0 4.6e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 BCS1 N terminal PIG-F PF06699.11 ORY10160.1 - 0.97 9.6 6.7 0.7 10.0 3.4 2.0 1 1 1 2 2 2 0 GPI biosynthesis protein family Pig-F DHDPS PF00701.22 ORY10161.1 - 3.6e-26 91.5 0.0 5.1e-26 91.0 0.0 1.2 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family DUF818 PF05677.12 ORY10161.1 - 0.18 10.7 0.1 0.27 10.1 0.1 1.1 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) MR_MLE_C PF13378.6 ORY10162.1 - 2.3e-58 197.4 0.0 2.9e-58 197.0 0.0 1.1 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 ORY10162.1 - 2.2e-16 60.1 0.0 4.4e-16 59.1 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MAAL_C PF07476.11 ORY10162.1 - 0.16 11.1 0.0 0.6 9.2 0.0 1.8 1 1 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus Fungal_trans PF04082.18 ORY10163.1 - 5e-29 101.2 0.1 1.1e-28 100.0 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY10163.1 - 3.8e-07 30.1 12.1 7.3e-07 29.2 12.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DLH PF01738.18 ORY10166.1 - 2.2e-32 112.4 0.0 2.5e-32 112.2 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Cir_N PF10197.9 ORY10167.1 - 0.00031 20.8 0.5 0.00031 20.8 0.5 5.6 6 1 1 7 7 7 1 N-terminal domain of CBF1 interacting co-repressor CIR PRP1_N PF06424.12 ORY10169.1 - 7.6e-45 152.9 6.8 1.3e-27 97.0 3.1 2.8 2 0 0 2 2 2 2 PRP1 splicing factor, N-terminal TPR_14 PF13428.6 ORY10169.1 - 1.3e-23 81.6 27.6 0.00065 20.3 0.0 13.7 5 3 10 15 15 15 6 Tetratricopeptide repeat TPR_19 PF14559.6 ORY10169.1 - 4.9e-18 65.4 22.9 0.00082 19.8 0.0 10.1 7 2 5 12 12 12 6 Tetratricopeptide repeat TPR_8 PF13181.6 ORY10169.1 - 2.3e-07 30.5 4.8 1.1 9.7 0.1 6.9 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 ORY10169.1 - 1e-06 28.4 15.4 4 7.8 0.1 9.7 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_1 PF00515.28 ORY10169.1 - 3.2e-05 23.6 6.3 2.2 8.2 0.0 5.8 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_15 PF13429.6 ORY10169.1 - 7e-05 22.2 6.2 7e-05 22.2 6.2 5.5 2 1 4 6 6 6 2 Tetratricopeptide repeat Suf PF05843.14 ORY10169.1 - 0.00015 21.9 0.1 0.013 15.5 0.0 3.5 2 2 0 3 3 3 1 Suppressor of forked protein (Suf) TPR_12 PF13424.6 ORY10169.1 - 0.00035 20.8 13.6 0.012 15.9 0.4 7.0 7 2 1 8 8 8 1 Tetratricopeptide repeat NRDE-2 PF08424.10 ORY10169.1 - 0.00067 18.9 16.5 0.012 14.8 0.2 5.2 3 1 2 5 5 5 1 NRDE-2, necessary for RNA interference Wzy_C_2 PF11846.8 ORY10169.1 - 0.0011 18.9 2.4 1.3 8.9 0.2 3.2 2 1 1 3 3 3 2 Virulence factor membrane-bound polymerase, C-terminal ANAPC3 PF12895.7 ORY10169.1 - 0.0015 18.7 5.5 0.16 12.2 0.5 4.0 3 1 2 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 SNAP PF14938.6 ORY10169.1 - 0.028 13.9 11.6 0.76 9.2 0.3 4.3 3 1 1 4 4 4 0 Soluble NSF attachment protein, SNAP TPR_6 PF13174.6 ORY10169.1 - 0.034 14.8 15.6 2.8 8.8 0.0 8.1 9 1 0 9 9 9 0 Tetratricopeptide repeat NARP1 PF12569.8 ORY10169.1 - 0.048 12.6 9.3 0.42 9.5 0.2 5.2 4 1 3 7 7 7 0 NMDA receptor-regulated protein 1 DinB PF05163.12 ORY10169.1 - 0.064 13.2 1.6 0.16 11.9 0.1 2.4 2 0 0 2 2 2 0 DinB family TPR_11 PF13414.6 ORY10169.1 - 0.14 11.9 7.6 15 5.4 0.4 5.7 7 1 1 8 8 8 0 TPR repeat TPR_16 PF13432.6 ORY10169.1 - 0.22 12.2 19.6 1 10.0 0.2 7.1 5 1 1 8 8 6 0 Tetratricopeptide repeat TPR_10 PF13374.6 ORY10169.1 - 1.1 9.2 9.0 8 6.5 0.1 5.1 4 0 0 4 4 4 0 Tetratricopeptide repeat SAGA-Tad1 PF12767.7 ORY10170.1 - 1.1e-59 202.1 0.0 1.6e-59 201.5 0.0 1.2 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit DUF4597 PF15366.6 ORY10170.1 - 0.14 11.9 0.4 0.36 10.6 0.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4597) Gcn1_N PF12074.8 ORY10171.1 - 3.9e-121 404.7 4.2 1.9e-120 402.4 0.1 3.6 3 1 1 4 4 4 1 Generalcontrol nonderepressible 1 (Gcn1) N-terminal HEAT PF02985.22 ORY10171.1 - 1.5e-34 115.0 29.2 0.046 14.0 0.1 20.6 21 0 0 21 21 19 11 HEAT repeat HEAT_EZ PF13513.6 ORY10171.1 - 1.3e-33 115.0 42.4 2.6e-06 27.8 0.0 19.7 16 3 6 22 22 20 10 HEAT-like repeat HEAT_2 PF13646.6 ORY10171.1 - 2.8e-25 88.5 42.8 1.3e-05 25.5 0.0 15.1 10 4 8 18 18 16 10 HEAT repeats Cnd1 PF12717.7 ORY10171.1 - 8.1e-19 68.2 6.9 0.048 13.7 0.1 10.6 8 3 2 11 11 10 4 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 ORY10171.1 - 1.6e-15 57.4 0.0 0.32 11.6 0.0 9.5 7 3 2 9 9 9 3 Vacuolar 14 Fab1-binding region ParcG PF10274.9 ORY10171.1 - 6.1e-13 49.3 3.4 0.00034 20.8 0.0 7.8 7 0 0 7 7 7 3 Parkin co-regulated protein UME PF08064.13 ORY10171.1 - 2.6e-09 36.9 0.8 5 7.1 0.0 9.1 8 2 2 10 10 9 2 UME (NUC010) domain CLASP_N PF12348.8 ORY10171.1 - 2.3e-07 30.6 0.0 3.9 7.0 0.0 5.8 3 1 2 5 5 5 3 CLASP N terminal Adaptin_N PF01602.20 ORY10171.1 - 1.1e-06 27.5 15.6 0.27 9.7 0.0 7.0 4 3 2 6 6 6 3 Adaptin N terminal region TIP120 PF08623.10 ORY10171.1 - 2.5e-05 24.1 0.1 0.42 10.4 0.0 6.1 5 1 1 6 6 6 1 TATA-binding protein interacting (TIP20) MMS19_C PF12460.8 ORY10171.1 - 0.0057 15.8 0.0 0.0057 15.8 0.0 7.2 6 2 3 9 9 8 3 RNAPII transcription regulator C-terminal RIX1 PF08167.12 ORY10171.1 - 0.0068 16.2 8.4 0.17 11.6 0.1 5.5 6 0 0 6 6 5 1 rRNA processing/ribosome biogenesis FANCI_S2 PF14676.6 ORY10171.1 - 0.012 15.9 0.3 6.3 7.1 0.0 3.6 2 1 0 2 2 2 0 FANCI solenoid 2 Dopey_N PF04118.14 ORY10171.1 - 0.034 13.2 1.9 31 3.5 0.0 5.1 5 2 1 6 6 6 0 Dopey, N-terminal Tti2 PF10521.9 ORY10171.1 - 0.14 11.7 5.0 4.6 6.7 0.0 5.7 7 0 0 7 7 7 0 Tti2 family TFCD_C PF12612.8 ORY10171.1 - 0.59 9.9 2.3 11 5.8 0.0 4.2 5 0 0 5 5 5 0 Tubulin folding cofactor D C terminal Cohesin_HEAT PF12765.7 ORY10171.1 - 0.62 10.4 7.6 19 5.6 0.0 6.0 6 0 0 6 6 4 0 HEAT repeat associated with sister chromatid cohesion V-ATPase_H_N PF03224.14 ORY10171.1 - 2.8 7.1 6.5 8.1 5.6 0.0 4.3 5 0 0 5 5 5 0 V-ATPase subunit H Telomere_reg-2 PF10193.9 ORY10171.1 - 3.4 8.1 6.1 27 5.3 0.0 5.4 4 1 1 5 5 5 0 Telomere length regulation protein RTP1_C1 PF10363.9 ORY10171.1 - 4.1 7.6 14.4 14 5.9 0.0 7.5 10 1 1 11 11 10 0 Required for nuclear transport of RNA pol II C-terminus 1 TrwB_AAD_bind PF10412.9 ORY10172.1 - 0.0051 15.8 0.3 0.0078 15.2 0.3 1.2 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain Hid1 PF12722.7 ORY10172.1 - 1.3 7.0 5.6 1.9 6.5 5.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SPT6_acidic PF14632.6 ORY10172.1 - 2.3 8.8 5.9 6.2 7.5 5.9 1.7 1 0 0 1 1 1 0 Acidic N-terminal SPT6 DUF3381 PF11861.8 ORY10172.1 - 10 5.9 11.8 20 4.9 11.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) NigD_C PF17415.2 ORY10175.1 - 0.0075 16.3 0.0 0.26 11.4 0.0 2.7 1 1 1 3 3 3 1 NigD-like C-terminal beta sandwich domain DUF3328 PF11807.8 ORY10176.1 - 8.4e-61 205.5 0.2 1e-60 205.3 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Aminotran_3 PF00202.21 ORY10177.1 - 4.2e-46 157.4 0.6 7.9e-45 153.2 0.2 2.6 3 1 0 3 3 3 1 Aminotransferase class-III MFS_1 PF07690.16 ORY10178.1 - 2.3e-23 82.7 47.9 2.3e-23 82.7 47.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily YqzM PF14141.6 ORY10178.1 - 0.64 10.1 5.2 4.6 7.4 0.4 3.2 2 0 0 2 2 2 0 YqzM-like protein Pyridoxal_deC PF00282.19 ORY10179.1 - 2.4e-21 75.9 0.0 5.1e-21 74.8 0.0 1.4 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_1_2 PF00155.21 ORY10179.1 - 0.00027 20.2 0.0 0.00041 19.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II SepSecS PF05889.13 ORY10179.1 - 0.0073 15.0 0.0 0.011 14.5 0.0 1.2 1 0 0 1 1 1 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Beta_elim_lyase PF01212.21 ORY10179.1 - 0.0091 15.3 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Acetyltransf_10 PF13673.7 ORY10182.1 - 6.6e-07 29.3 0.0 2e-06 27.8 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORY10182.1 - 2.4e-05 24.5 0.0 3.6e-05 24.0 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ORY10182.1 - 7.7e-05 23.1 0.0 0.00014 22.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 ORY10182.1 - 0.044 13.9 0.2 0.14 12.3 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain adh_short_C2 PF13561.6 ORY10183.1 - 3.6e-13 49.6 0.0 4.2e-13 49.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY10183.1 - 3.4e-10 39.7 0.0 3.8e-10 39.5 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase HET PF06985.11 ORY10184.1 - 5.8e-30 104.6 0.6 9e-30 103.9 0.6 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.7 ORY10185.1 - 4.1e-17 62.5 0.0 2.7e-08 34.3 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY10185.1 - 4.9e-10 39.7 0.0 1.5e-06 28.6 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 ORY10185.1 - 2.3e-08 34.1 0.1 0.065 13.7 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 ORY10185.1 - 5.1e-07 29.5 0.0 0.014 15.9 0.0 4.0 4 0 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.6 ORY10185.1 - 6.9e-07 29.4 0.0 0.00035 20.8 0.0 2.8 1 1 2 3 3 3 2 Ankyrin repeats (many copies) XLF PF09302.11 ORY10185.1 - 0.02 15.1 0.0 0.06 13.5 0.0 1.7 2 0 0 2 2 2 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component FAD_binding_4 PF01565.23 ORY10186.1 - 5.8e-23 81.2 0.6 1.1e-22 80.2 0.6 1.5 1 0 0 1 1 1 1 FAD binding domain Lactamase_B PF00753.27 ORY10187.1 - 1e-07 32.2 0.2 1.6e-07 31.6 0.2 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 ORY10187.1 - 0.0038 16.8 0.1 0.0062 16.1 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain HCV_NS2 PF01538.18 ORY10187.1 - 0.26 10.9 0.0 0.36 10.5 0.0 1.1 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein NS2 MFS_1 PF07690.16 ORY10188.1 - 1.1e-06 27.8 38.7 8.3e-06 25.0 30.0 3.0 2 1 0 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_71 PF03659.14 ORY10189.1 - 5.3e-95 318.4 1.7 6.5e-95 318.1 1.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 NDT80_PhoG PF05224.12 ORY10190.1 - 0.0031 17.8 0.0 0.0046 17.2 0.0 1.4 1 1 0 1 1 1 1 NDT80 / PhoG like DNA-binding family Glyco_hydro_31 PF01055.26 ORY10191.1 - 4.6e-94 316.1 0.1 5.8e-94 315.8 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 ORY10191.1 - 1.3e-10 41.4 0.0 3.9e-10 39.9 0.0 1.8 1 0 0 1 1 1 1 Galactose mutarotase-like MFS_1 PF07690.16 ORY10192.1 - 1.8e-32 112.6 31.6 1.8e-32 112.6 31.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3671 PF12420.8 ORY10192.1 - 0.54 10.4 7.5 0.85 9.7 0.4 3.6 4 1 0 4 4 4 0 Protein of unknown function Vma12 PF11712.8 ORY10192.1 - 7.5 6.6 6.0 40 4.3 1.2 3.1 2 1 1 3 3 3 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Zn_clus PF00172.18 ORY10193.1 - 1e-08 35.2 10.6 1.8e-08 34.4 10.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2975 PF11188.8 ORY10196.1 - 2.5 8.0 7.1 4.5 7.2 7.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2975) MSC PF09402.10 ORY10197.1 - 7.5e-56 190.0 0.0 1.3e-55 189.2 0.0 1.3 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.7 ORY10197.1 - 1.8e-14 53.1 0.1 3.5e-14 52.2 0.1 1.5 1 0 0 1 1 1 1 HeH/LEM domain Endonuc-dimeris PF09124.10 ORY10197.1 - 0.0055 16.9 0.0 0.027 14.6 0.0 2.1 2 0 0 2 2 2 1 T4 recombination endonuclease VII, dimerisation NACHT PF05729.12 ORY10198.1 - 5.3e-12 46.0 0.0 1.4e-11 44.6 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 ORY10198.1 - 0.00011 22.5 0.0 0.00046 20.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 ORY10198.1 - 0.0019 18.6 0.2 0.014 15.8 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 ORY10198.1 - 0.021 15.2 0.0 0.065 13.7 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 ORY10198.1 - 0.064 13.6 0.0 0.17 12.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Parvo_NS1 PF01057.17 ORY10198.1 - 0.18 10.8 0.0 0.37 9.8 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ApbA_C PF08546.11 ORY10199.1 - 4.7e-26 91.4 0.0 7.5e-26 90.8 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 ORY10199.1 - 2e-22 79.5 0.0 2.8e-22 79.0 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.6 ORY10199.1 - 0.018 15.5 0.0 0.033 14.6 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding DAO PF01266.24 ORY10199.1 - 0.034 13.7 3.1 0.16 11.5 2.7 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase ThiF PF00899.21 ORY10199.1 - 0.073 12.4 1.1 0.14 11.5 1.1 1.4 1 0 0 1 1 1 0 ThiF family FAD_binding_3 PF01494.19 ORY10199.1 - 0.13 11.4 1.0 0.21 10.8 1.0 1.3 1 0 0 1 1 1 0 FAD binding domain FAD_binding_2 PF00890.24 ORY10199.1 - 0.88 8.6 4.0 1.7 7.7 3.9 1.5 2 0 0 2 2 2 0 FAD binding domain Ribosomal_L44 PF00935.19 ORY10200.1 - 1.7e-36 124.5 11.4 2.6e-36 124.0 11.4 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 Response_reg PF00072.24 ORY10202.1 - 7e-11 42.3 0.1 1.5e-10 41.2 0.1 1.5 1 1 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 ORY10203.1 - 3.2e-12 46.9 0.0 4.1e-12 46.6 0.0 1.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 ORY10203.1 - 0.15 11.9 0.0 0.46 10.3 0.0 1.7 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase F-box-like PF12937.7 ORY10204.1 - 0.011 15.7 0.0 0.027 14.4 0.0 1.6 1 0 0 1 1 1 0 F-box-like F-box PF00646.33 ORY10204.1 - 0.017 15.0 0.0 0.05 13.5 0.0 1.7 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.7 ORY10205.1 - 0.01 15.7 0.9 0.021 14.7 0.9 1.5 1 0 0 1 1 1 0 F-box-like Hydantoinase_B PF02538.14 ORY10206.1 - 3.7e-216 718.5 0.0 5.2e-216 718.0 0.0 1.2 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 ORY10206.1 - 5.4e-103 344.2 1.2 8.3e-103 343.6 0.2 1.9 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 ORY10206.1 - 2.3e-61 206.6 0.9 7.7e-60 201.6 0.0 2.6 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region GP41 PF00517.17 ORY10207.1 - 0.036 14.0 1.0 0.12 12.3 0.0 2.0 2 0 0 2 2 2 0 Retroviral envelope protein DUF1366 PF07104.11 ORY10207.1 - 0.056 13.1 0.7 0.13 11.9 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1366) RIC3 PF15361.6 ORY10207.1 - 0.31 11.4 2.5 0.7 10.3 2.5 1.5 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 DUF2570 PF10828.8 ORY10207.1 - 0.36 10.7 8.1 0.17 11.7 2.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) MIP PF00230.20 ORY10208.1 - 1.8e-28 99.8 5.9 2.6e-28 99.3 5.9 1.3 1 0 0 1 1 1 1 Major intrinsic protein p450 PF00067.22 ORY10209.1 - 8.7e-49 166.5 0.0 1.1e-48 166.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 HET PF06985.11 ORY10210.1 - 2.4e-24 86.3 1.1 4.5e-24 85.5 1.1 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MutS_V PF00488.21 ORY10211.1 - 4.3e-82 274.7 0.4 8.3e-82 273.8 0.4 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 ORY10211.1 - 1e-34 120.5 1.1 1e-34 120.5 1.1 2.0 2 1 0 2 2 2 1 MutS domain III MutS_II PF05188.17 ORY10211.1 - 9e-20 71.4 4.4 2e-19 70.2 0.0 3.1 3 0 0 3 3 3 1 MutS domain II MutS_IV PF05190.18 ORY10211.1 - 6.4e-19 68.1 2.1 6.4e-19 68.1 2.1 2.6 2 0 0 2 2 2 1 MutS family domain IV MutS_I PF01624.20 ORY10211.1 - 1.3e-18 67.3 0.1 9.4e-18 64.5 0.0 2.4 2 1 0 2 2 2 1 MutS domain I MbeD_MobD PF04899.12 ORY10211.1 - 0.019 15.0 0.0 0.13 12.4 0.0 2.4 1 0 0 1 1 1 0 MbeD/MobD like Cytochrom_B561 PF03188.16 ORY10212.1 - 1.1e-18 67.6 4.5 1.1e-18 67.6 4.5 1.5 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 DUF2157 PF09925.9 ORY10212.1 - 0.16 11.7 11.1 0.2 11.4 0.5 2.4 2 1 0 2 2 2 0 Predicted membrane protein (DUF2157) DUF3285 PF11688.8 ORY10212.1 - 0.21 11.5 1.3 0.7 9.9 1.3 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3285) Ni_hydr_CYTB PF01292.20 ORY10212.1 - 0.51 9.9 14.3 2.5 7.6 7.8 2.9 1 1 1 2 2 2 0 Prokaryotic cytochrome b561 DUF2306 PF10067.9 ORY10212.1 - 2.6 8.2 12.0 0.1 12.8 2.1 2.7 1 1 2 3 3 3 0 Predicted membrane protein (DUF2306) PepSY_TM PF03929.16 ORY10212.1 - 8.8 5.9 13.1 0.16 11.6 3.7 2.4 1 1 1 2 2 2 0 PepSY-associated TM region Sema PF01403.19 ORY10213.1 - 0.054 12.3 0.3 0.063 12.1 0.3 1.0 1 0 0 1 1 1 0 Sema domain p450 PF00067.22 ORY10228.1 - 1.1e-07 31.0 1.5 3.3e-07 29.4 0.8 2.1 2 1 0 2 2 2 1 Cytochrome P450 TFIIS_C PF01096.18 ORY10229.1 - 0.44 10.5 4.9 1.3 8.9 0.5 2.4 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) zf-HIT PF04438.16 ORY10229.1 - 1.5 8.8 8.3 7.3 6.6 0.9 2.4 2 0 0 2 2 2 0 HIT zinc finger BTB PF00651.31 ORY10230.1 - 8.3e-07 29.2 0.0 9.7e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 BTB/POZ domain SET PF00856.28 ORY10231.1 - 1.7e-15 57.8 0.2 1.2e-14 55.0 0.2 2.1 1 1 0 1 1 1 1 SET domain DnaJ PF00226.31 ORY10232.1 - 9.1e-17 60.9 0.3 9.1e-17 60.9 0.3 2.1 2 0 0 2 2 2 1 DnaJ domain CDC45 PF02724.14 ORY10232.1 - 0.74 8.0 24.4 0.9 7.8 24.4 1.2 1 0 0 1 1 1 0 CDC45-like protein SOBP PF15279.6 ORY10232.1 - 1.9 9.0 5.3 2.9 8.4 5.3 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein Zot PF05707.12 ORY10233.1 - 0.00076 19.2 0.0 0.0036 17.0 0.0 1.9 2 0 0 2 2 2 1 Zonular occludens toxin (Zot) DUF87 PF01935.17 ORY10233.1 - 0.0046 17.1 0.0 3.9 7.5 0.0 2.7 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_22 PF13401.6 ORY10233.1 - 0.011 16.0 0.1 7.9 6.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF853 PF05872.12 ORY10233.1 - 0.039 12.6 0.0 0.059 11.9 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) p450 PF00067.22 ORY10234.1 - 3.7e-26 91.9 0.0 1.2e-25 90.3 0.0 1.7 2 0 0 2 2 2 1 Cytochrome P450 DUF3433 PF11915.8 ORY10235.1 - 2.1e-15 56.9 6.0 2.1e-15 56.9 6.0 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3433) AtuA PF07287.11 ORY10238.1 - 1.6e-71 240.8 3.3 1.2e-69 234.7 3.3 2.3 1 1 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA Cyclase PF04199.13 ORY10239.1 - 7.9e-09 35.9 0.0 1.1e-08 35.4 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase Cupin_3 PF05899.12 ORY10239.1 - 0.055 13.2 0.1 0.22 11.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF861) MARVEL PF01284.23 ORY10240.1 - 1.9 8.5 12.8 15 5.6 12.4 2.6 1 1 0 1 1 1 0 Membrane-associating domain SET PF00856.28 ORY10241.1 - 2e-10 41.3 3.7 6.5e-10 39.6 0.1 3.0 2 2 0 2 2 2 1 SET domain TPR_2 PF07719.17 ORY10241.1 - 0.00034 20.5 4.9 0.8 10.0 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 ORY10241.1 - 0.1 12.8 3.2 0.5 10.7 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 ORY10241.1 - 6.7 6.7 8.4 22 5.1 1.5 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat DHH PF01368.20 ORY10244.1 - 0.0051 17.0 0.0 0.0089 16.2 0.0 1.4 1 0 0 1 1 1 1 DHH family p450 PF00067.22 ORY10246.1 - 7.8e-78 262.3 0.0 1e-77 261.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SNRNP27 PF08648.12 ORY10248.1 - 1.2e-22 79.7 0.8 2e-22 79.0 0.8 1.3 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins Glyco_hydro_63 PF03200.16 ORY10249.1 - 1.5e-172 574.8 3.7 3.8e-171 570.2 0.4 3.5 3 1 0 3 3 3 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 ORY10249.1 - 5.7e-85 285.0 0.0 1.5e-84 283.6 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 63 N-terminal domain Trehalase PF01204.18 ORY10249.1 - 6.9e-05 21.9 1.6 8.3e-05 21.6 0.1 1.7 2 0 0 2 2 2 1 Trehalase Surface_Ag_2 PF01617.17 ORY10249.1 - 0.11 11.9 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Surface antigen Elong_Iki1 PF10483.9 ORY10250.1 - 2.4e-63 214.4 0.0 3.2e-63 214.0 0.0 1.1 1 0 0 1 1 1 1 Elongator subunit Iki1 adh_short PF00106.25 ORY10251.1 - 6.8e-21 74.6 0.0 1.1e-20 74.0 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY10251.1 - 2.6e-15 56.6 0.0 4.2e-15 55.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Peroxidase_2 PF01328.17 ORY10253.1 - 1.6e-42 146.2 0.0 2.3e-42 145.6 0.0 1.2 1 0 0 1 1 1 1 Peroxidase, family 2 Sld7_C PF18596.1 ORY10254.1 - 1.9e-28 98.4 0.1 3.2e-28 97.7 0.1 1.4 1 0 0 1 1 1 1 Sld7 C-terminal domain Sld7_N PF18636.1 ORY10254.1 - 0.07 13.5 0.0 0.23 11.8 0.0 1.8 2 0 0 2 2 2 0 Mitochondrial morphogenesis protein SLD7 N-terminal domain BBE PF08031.12 ORY10255.1 - 0.019 15.0 0.1 0.028 14.5 0.1 1.3 1 1 0 1 1 1 0 Berberine and berberine like Glyco_hydro_12 PF01670.16 ORY10256.1 - 1.6e-47 162.3 12.4 7.6e-35 120.8 2.7 2.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 12 C2-set_2 PF08205.12 ORY10256.1 - 0.022 14.8 0.2 0.049 13.7 0.2 1.5 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain StbA PF06406.11 ORY10256.1 - 0.046 13.0 0.1 0.075 12.3 0.1 1.3 1 0 0 1 1 1 0 StbA protein E1-E2_ATPase PF00122.20 ORY10258.1 - 5.7e-37 127.0 14.2 6.6e-37 126.8 3.4 3.8 4 1 0 4 4 4 2 E1-E2 ATPase Hydrolase PF00702.26 ORY10258.1 - 6.6e-17 62.5 0.1 1.6e-16 61.2 0.1 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 ORY10258.1 - 2e-11 43.4 0.0 4.6e-11 42.2 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 ORY10258.1 - 0.0053 16.5 0.0 0.013 15.2 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 ORY10258.1 - 0.01 15.9 0.0 0.023 14.8 0.0 1.5 1 0 0 1 1 1 0 Cation transport ATPase (P-type) F-box PF00646.33 ORY10259.1 - 0.0075 16.1 0.4 0.019 14.8 0.4 1.7 1 0 0 1 1 1 1 F-box domain Peptidase_S41 PF03572.18 ORY10260.1 - 3.2e-09 36.6 0.0 9.3e-09 35.1 0.0 1.7 1 1 0 1 1 1 1 Peptidase family S41 SesA PF17107.5 ORY10262.1 - 9.7e-11 41.9 3.0 1.2e-10 41.6 0.1 2.8 4 0 0 4 4 3 1 N-terminal domain on NACHT_NTPase and P-loop NTPases NACHT PF05729.12 ORY10262.1 - 1e-06 28.8 3.1 1.2e-06 28.6 0.0 2.7 3 1 0 3 3 3 1 NACHT domain AAA_16 PF13191.6 ORY10262.1 - 9.6e-06 26.1 0.1 7.8e-05 23.1 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.6 ORY10262.1 - 0.0023 17.7 0.1 0.12 12.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain Helo_like_N PF17111.5 ORY10262.1 - 0.0025 17.2 1.8 0.0079 15.6 1.5 2.0 2 0 0 2 2 2 1 Fungal N-terminal domain of STAND proteins AAA_22 PF13401.6 ORY10262.1 - 0.0027 18.0 0.0 0.045 14.0 0.0 2.9 2 1 0 2 2 2 1 AAA domain ABC_tran PF00005.27 ORY10262.1 - 0.013 16.0 0.0 0.056 14.0 0.0 2.1 1 0 0 1 1 1 0 ABC transporter TPR_12 PF13424.6 ORY10262.1 - 0.019 15.3 0.3 3 8.2 0.4 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat RNA_helicase PF00910.22 ORY10262.1 - 0.021 15.2 0.1 0.081 13.3 0.0 2.0 2 0 0 2 2 1 0 RNA helicase RsgA_GTPase PF03193.16 ORY10262.1 - 0.024 14.6 0.0 0.06 13.3 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase AAA_33 PF13671.6 ORY10262.1 - 0.041 14.0 0.4 1.7 8.8 0.0 3.4 2 1 1 3 3 3 0 AAA domain ATPase_2 PF01637.18 ORY10262.1 - 0.055 13.4 0.0 0.17 11.8 0.0 1.8 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA PF00004.29 ORY10262.1 - 0.06 13.8 0.5 0.78 10.2 0.0 3.1 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 ORY10262.1 - 0.06 12.5 0.0 0.59 9.3 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain AAA_29 PF13555.6 ORY10262.1 - 0.083 12.6 0.0 0.26 11.1 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.6 ORY10262.1 - 0.13 12.8 0.0 0.49 10.9 0.0 2.0 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 ORY10262.1 - 0.14 11.5 0.0 0.63 9.3 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin MMR_HSR1 PF01926.23 ORY10262.1 - 0.17 12.0 0.0 0.66 10.1 0.0 2.0 2 0 0 2 2 1 0 50S ribosome-binding GTPase DUF1987 PF09345.10 ORY10262.1 - 0.19 11.4 0.4 2.5 7.8 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1987) DUF87 PF01935.17 ORY10262.1 - 0.98 9.5 2.9 17 5.4 0.1 3.1 3 0 0 3 3 3 0 Helicase HerA, central domain CorA PF01544.18 ORY10264.1 - 0.021 14.2 15.5 0.051 12.9 4.2 2.3 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein HSA PF07529.13 ORY10264.1 - 0.041 14.2 0.4 0.11 12.8 0.4 1.7 1 0 0 1 1 1 0 HSA MbeD_MobD PF04899.12 ORY10264.1 - 1.1 9.4 4.9 0.79 9.9 1.7 2.4 2 0 0 2 2 2 0 MbeD/MobD like Ribosomal_L28e PF01778.17 ORY10268.1 - 4.3e-36 124.2 0.6 8.9e-36 123.1 0.6 1.5 1 0 0 1 1 1 1 Ribosomal L28e protein family Mak16 PF04874.14 ORY10268.1 - 2.1e-27 95.6 7.4 2.1e-27 95.6 7.4 2.5 2 0 0 2 2 2 1 Mak16 protein C-terminal region BUD22 PF09073.10 ORY10268.1 - 1e-05 25.1 11.7 1.3e-05 24.7 11.7 1.1 1 0 0 1 1 1 1 BUD22 SDA1 PF05285.12 ORY10268.1 - 0.21 11.0 20.8 0.3 10.5 20.8 1.3 1 0 0 1 1 1 0 SDA1 PYC_OADA PF02436.18 ORY10268.1 - 0.55 10.0 2.2 0.4 10.4 0.1 1.9 2 0 0 2 2 2 0 Conserved carboxylase domain Nop14 PF04147.12 ORY10268.1 - 1.4 7.1 25.6 0.37 8.9 22.4 1.5 2 0 0 2 2 2 0 Nop14-like family Sporozoite_P67 PF05642.11 ORY10268.1 - 5 5.1 10.3 8.7 4.3 10.3 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CDC45 PF02724.14 ORY10268.1 - 5.7 5.1 15.5 8.4 4.6 15.5 1.2 1 0 0 1 1 1 0 CDC45-like protein TrmE_N PF10396.9 ORY10269.1 - 5.1e-34 117.1 0.0 1.2e-33 115.9 0.0 1.7 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus MnmE_helical PF12631.7 ORY10269.1 - 8.1e-29 101.3 0.0 2.4e-28 99.7 0.0 1.7 1 1 0 1 1 1 1 MnmE helical domain MMR_HSR1 PF01926.23 ORY10269.1 - 1.8e-19 69.9 0.1 3.1e-19 69.2 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 ORY10269.1 - 4.8e-09 35.9 0.0 1.4e-08 34.4 0.0 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 ORY10269.1 - 6.9e-07 29.0 0.0 0.00011 21.8 0.0 2.4 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 ORY10269.1 - 9.7e-06 25.7 0.2 6.9e-05 23.0 0.0 2.0 1 1 0 2 2 2 1 Dynamin family RsgA_GTPase PF03193.16 ORY10269.1 - 0.00052 20.0 0.1 0.22 11.4 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase ABC_tran PF00005.27 ORY10269.1 - 0.01 16.3 0.0 0.063 13.8 0.0 2.2 2 1 0 2 2 2 0 ABC transporter AAA_24 PF13479.6 ORY10269.1 - 0.15 11.7 0.0 0.33 10.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain zf_C2H2_6 PF18450.1 ORY10270.1 - 0.55 10.0 3.6 2.5 7.9 0.1 2.4 2 0 0 2 2 2 0 Zinc Finger domain Hus1 PF04005.12 ORY10271.1 - 8.6e-101 336.9 0.0 9.7e-101 336.7 0.0 1.0 1 0 0 1 1 1 1 Hus1-like protein Ank_2 PF12796.7 ORY10272.1 - 2.6e-22 79.2 0.0 4.9e-13 49.5 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ORY10272.1 - 2.4e-19 69.1 0.0 1.6e-09 37.8 0.0 3.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 ORY10272.1 - 7.7e-18 64.6 0.0 3.2e-09 37.1 0.0 3.6 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY10272.1 - 1.2e-12 46.7 0.0 0.049 14.2 0.0 4.7 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 ORY10272.1 - 1.1e-11 44.6 0.1 0.0047 17.3 0.0 4.6 4 0 0 4 4 4 2 Ankyrin repeat zf-C2H2_6 PF13912.6 ORY10272.1 - 0.0056 16.6 0.1 0.0056 16.6 0.1 3.3 4 0 0 4 4 4 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORY10272.1 - 0.0079 16.5 5.9 5.3 7.5 0.0 4.7 4 1 0 4 4 4 1 Zinc-finger double-stranded RNA-binding TRAP-delta PF05404.12 ORY10272.1 - 0.01 15.4 0.1 0.69 9.4 0.0 2.4 2 0 0 2 2 2 0 Translocon-associated protein, delta subunit precursor (TRAP-delta) zf-C2H2_4 PF13894.6 ORY10272.1 - 0.015 16.1 0.3 0.015 16.1 0.3 5.6 5 1 0 5 5 5 0 C2H2-type zinc finger zf-met PF12874.7 ORY10272.1 - 0.016 15.6 3.8 10 6.6 0.0 4.3 5 0 0 5 5 5 0 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 ORY10272.1 - 0.026 15.0 7.5 0.46 11.0 0.0 3.5 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2 PF00096.26 ORY10272.1 - 0.036 14.5 13.5 0.05 14.1 0.3 4.2 4 0 0 4 4 4 0 Zinc finger, C2H2 type Vps39_2 PF10367.9 ORY10272.1 - 0.11 13.0 0.2 0.33 11.4 0.2 1.9 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 Rad50_zn_hook PF04423.14 ORY10272.1 - 0.13 12.1 0.0 0.38 10.6 0.0 1.7 1 0 0 1 1 1 0 Rad50 zinc hook motif zf-C2H2_2 PF12756.7 ORY10272.1 - 0.73 10.2 8.7 0.38 11.1 1.8 3.3 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) DUF4734 PF15881.5 ORY10272.1 - 1.8 8.8 7.2 1.1 9.5 5.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4734) DUF2218 PF09981.9 ORY10273.1 - 0.21 12.0 0.7 1.4 9.3 0.7 2.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2218) Spore_YtfJ PF09579.10 ORY10274.1 - 0.00051 20.1 6.8 0.28 11.4 0.1 3.6 3 1 0 3 3 3 2 Sporulation protein YtfJ (Spore_YtfJ) CSS-motif PF12792.7 ORY10274.1 - 0.016 14.7 1.4 2.6 7.5 0.1 2.5 1 1 1 2 2 2 0 CSS motif domain associated with EAL Egh16-like PF11327.8 ORY10277.1 - 0.00012 22.5 4.4 0.00033 21.1 4.4 1.7 1 1 0 1 1 1 1 Egh16-like virulence factor ADH_N PF08240.12 ORY10278.1 - 3.3e-24 84.9 4.2 5.9e-24 84.1 4.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORY10278.1 - 2.6e-15 56.6 0.0 4.5e-15 55.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ORY10278.1 - 0.0012 19.9 0.0 0.0021 19.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ELFV_dehydrog PF00208.21 ORY10278.1 - 0.032 14.0 1.1 0.045 13.5 0.2 1.6 2 0 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Zn_Tnp_IS1 PF03811.13 ORY10278.1 - 0.054 13.2 0.1 0.21 11.3 0.1 2.0 1 0 0 1 1 1 0 InsA N-terminal domain TTC5_OB PF16669.5 ORY10278.1 - 0.059 13.1 0.0 0.2 11.4 0.0 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat protein 5 OB fold domain 2-Hacid_dh_C PF02826.19 ORY10278.1 - 0.15 11.4 0.1 0.25 10.7 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain MFS_1 PF07690.16 ORY10279.1 - 5.3e-32 111.1 55.5 7.6e-23 81.0 25.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.18 ORY10280.1 - 3e-15 56.0 0.0 5e-15 55.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY10280.1 - 3.2e-06 27.1 10.7 6e-06 26.3 10.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HSBP1 PF06825.12 ORY10280.1 - 0.083 12.8 0.2 0.18 11.7 0.2 1.5 1 0 0 1 1 1 0 Heat shock factor binding protein 1 Pox_A_type_inc PF04508.12 ORY10280.1 - 0.095 12.6 0.1 0.31 11.0 0.1 1.8 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat Amidohydro_2 PF04909.14 ORY10281.1 - 2.1e-09 37.6 0.0 2.8e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase Blt1 PF12754.7 ORY10282.1 - 0.038 14.3 0.3 0.07 13.4 0.3 1.4 1 0 0 1 1 1 0 Blt1 N-terminal domain T3SS_basalb_I PF17001.5 ORY10282.1 - 0.15 12.6 1.9 0.4 11.3 1.9 1.7 1 0 0 1 1 1 0 Type III secretion basal body protein I, YscI, HrpB, PscI PhageMin_Tail PF10145.9 ORY10282.1 - 0.53 10.1 13.6 1.1 9.0 13.6 1.5 1 1 0 1 1 1 0 Phage-related minor tail protein Asp PF00026.23 ORY10283.1 - 2.5e-60 204.5 3.0 3.3e-60 204.1 3.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 ORY10283.1 - 3.2e-13 50.3 2.1 1.8e-07 31.5 0.1 2.4 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal Rubella_E2 PF05749.11 ORY10284.1 - 0.048 13.1 2.4 0.073 12.5 2.4 1.2 1 0 0 1 1 1 0 Rubella membrane glycoprotein E2 Sporozoite_P67 PF05642.11 ORY10284.1 - 0.33 9.0 2.4 0.36 8.9 2.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen ADH_zinc_N_2 PF13602.6 ORY10285.1 - 1.4e-13 52.0 0.0 3.5e-13 50.8 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 ORY10285.1 - 1.7e-10 40.9 0.3 6.7e-10 39.1 0.0 2.1 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ORY10285.1 - 0.00045 20.1 0.2 0.036 13.9 0.0 3.0 1 1 2 3 3 3 1 Alcohol dehydrogenase GroES-like domain DUF2855 PF11017.8 ORY10285.1 - 0.017 14.9 0.0 0.028 14.2 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2855) DapB_N PF01113.20 ORY10285.1 - 0.058 13.5 0.0 0.94 9.6 0.0 2.3 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus But2 PF09792.9 ORY10286.1 - 7.1e-29 101.0 0.2 9.1e-29 100.7 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain MFS_1 PF07690.16 ORY10287.1 - 2.3e-32 112.3 28.2 2.3e-32 112.3 28.2 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY10287.1 - 3.8e-10 39.2 5.2 3.8e-10 39.2 5.2 2.8 3 0 0 3 3 3 1 Sugar (and other) transporter GerA PF03323.13 ORY10287.1 - 0.023 13.2 3.6 0.11 10.9 0.1 2.8 3 0 0 3 3 3 0 Bacillus/Clostridium GerA spore germination protein Fungal_trans_2 PF11951.8 ORY10303.1 - 8.3e-20 70.9 8.6 5.4e-16 58.4 7.5 3.1 2 1 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY10303.1 - 1.8e-07 31.1 11.5 3.1e-07 30.4 11.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BRO1 PF03097.18 ORY10305.1 - 5.6e-131 436.9 1.9 1.1e-130 436.0 1.9 1.5 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 ORY10305.1 - 3.6e-82 276.0 10.9 6.6e-82 275.1 10.9 1.5 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV DUF416 PF04222.12 ORY10305.1 - 0.00044 19.7 0.6 0.36 10.2 0.1 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF416) DUF2383 PF09537.10 ORY10305.1 - 0.015 15.7 3.5 0.9 9.9 0.1 4.5 5 0 0 5 5 5 0 Domain of unknown function (DUF2383) GCP_N_terminal PF17681.1 ORY10305.1 - 0.044 13.4 1.1 0.079 12.6 1.1 1.4 1 0 0 1 1 1 0 Gamma tubulin complex component N-terminal DnaJ_C PF01556.18 ORY10306.1 - 2.6e-37 128.2 0.1 3.8e-37 127.6 0.1 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 ORY10306.1 - 6.6e-23 80.6 2.8 7.2e-23 80.5 1.7 1.7 2 0 0 2 2 2 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 ORY10306.1 - 2.6e-08 34.1 22.4 5e-08 33.2 22.4 1.5 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.19 ORY10306.1 - 0.86 9.6 8.9 21 5.2 0.8 2.3 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 ORY10306.1 - 4.6 7.3 6.9 12 6.0 6.9 1.7 1 1 0 1 1 1 0 Double zinc ribbon SAP30_Sin3_bdg PF13867.6 ORY10307.1 - 3.1e-08 33.8 0.1 0.00017 21.8 0.0 2.3 2 0 0 2 2 2 2 Sin3 binding region of histone deacetylase complex subunit SAP30 Bestrophin PF01062.21 ORY10309.1 - 1.9e-36 126.0 0.1 3e-36 125.3 0.1 1.2 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel CcmB PF03379.13 ORY10309.1 - 0.039 13.4 0.2 0.09 12.3 0.2 1.5 1 0 0 1 1 1 0 CcmB protein Med9 PF07544.13 ORY10312.1 - 0.014 15.5 0.3 0.016 15.3 0.3 1.1 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Ank_2 PF12796.7 ORY10313.1 - 5.5e-22 78.2 2.3 1.8e-08 34.8 0.3 3.7 1 1 3 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ORY10313.1 - 6.4e-12 45.5 0.5 4.8e-07 29.9 0.1 4.7 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Ank PF00023.30 ORY10313.1 - 3e-10 40.1 6.4 0.0013 19.0 0.1 4.1 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 ORY10313.1 - 4e-10 39.0 3.3 0.015 15.8 0.2 5.2 6 0 0 6 6 6 3 Ankyrin repeat Ank_4 PF13637.6 ORY10313.1 - 1.5e-08 35.0 0.9 3.1e-06 27.6 0.1 3.8 3 1 2 5 5 5 2 Ankyrin repeats (many copies) F-box-like PF12937.7 ORY10313.1 - 0.04 13.8 0.7 0.11 12.4 0.7 1.8 1 0 0 1 1 1 0 F-box-like Abhydro_lipase PF04083.16 ORY10313.1 - 0.077 12.6 0.0 0.28 10.8 0.0 2.0 1 1 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region F_actin_bind PF08919.10 ORY10314.1 - 0.028 14.5 0.5 0.094 12.8 0.1 2.0 2 0 0 2 2 2 0 F-actin binding FIBP PF05427.11 ORY10314.1 - 0.13 11.6 0.1 0.23 10.7 0.1 1.3 1 0 0 1 1 1 0 Acidic fibroblast growth factor binding (FIBP) NUDIX PF00293.28 ORY10316.1 - 1.1e-21 77.2 0.4 1.4e-21 76.9 0.4 1.0 1 0 0 1 1 1 1 NUDIX domain Rep_1B PF17873.1 ORY10316.1 - 0.025 14.5 0.1 0.042 13.7 0.1 1.4 1 0 0 1 1 1 0 Replicase polyprotein 1ab MFS_1 PF07690.16 ORY10317.1 - 2.2e-36 125.5 46.3 2.2e-36 125.5 46.3 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily LysM PF01476.20 ORY10318.1 - 4e-05 23.6 2.3 5.6e-05 23.1 0.1 2.3 3 0 0 3 3 3 1 LysM domain DUF5102 PF17104.5 ORY10319.1 - 0.12 12.4 0.2 0.17 11.9 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5102) Cys_Met_Meta_PP PF01053.20 ORY10320.1 - 3.5e-137 457.0 0.0 4.1e-137 456.8 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 ORY10320.1 - 1.4e-06 27.8 0.0 2e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Met_gamma_lyase PF06838.11 ORY10320.1 - 1.8e-05 23.4 0.0 0.00011 20.9 0.0 1.9 1 1 0 1 1 1 1 Methionine gamma-lyase Aminotran_5 PF00266.19 ORY10320.1 - 6.5e-05 22.0 0.0 0.00012 21.2 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 ORY10320.1 - 0.00036 20.0 0.0 0.00068 19.1 0.0 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family GDC-P PF02347.16 ORY10320.1 - 0.0035 16.2 0.0 0.0075 15.2 0.0 1.5 1 1 1 2 2 2 1 Glycine cleavage system P-protein TQ PF18202.1 ORY10320.1 - 0.13 12.7 0.2 0.42 11.2 0.3 1.7 2 0 0 2 2 2 0 T-Q ester bond containing domain DUF2415 PF10313.9 ORY10321.1 - 9e-15 54.3 0.0 2.4e-14 53.0 0.0 1.8 1 0 0 1 1 1 1 Uncharacterised protein domain (DUF2415) PQQ_3 PF13570.6 ORY10321.1 - 0.028 14.9 2.9 1.1e+02 3.5 0.0 4.6 4 0 0 4 4 4 0 PQQ-like domain WD40 PF00400.32 ORY10321.1 - 0.052 14.4 0.5 66 4.6 0.0 4.8 5 0 0 5 5 5 0 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY10321.1 - 0.064 13.6 0.0 1.9 8.8 0.0 2.9 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain HSP70 PF00012.20 ORY10322.1 - 2.9e-267 887.7 18.0 3.4e-267 887.5 18.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 ORY10322.1 - 2.4e-13 49.6 6.5 4e-12 45.6 3.3 2.5 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 ORY10322.1 - 0.00033 20.4 0.0 0.00082 19.2 0.0 1.8 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 ORY10322.1 - 0.015 15.7 8.1 0.6 10.6 0.5 4.2 3 2 0 3 3 3 0 Cell division protein FtsA DUF4363 PF14276.6 ORY10322.1 - 0.13 12.4 6.2 0.31 11.2 6.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4363) SMBP PF16785.5 ORY10322.1 - 0.16 12.2 7.7 0.059 13.6 4.3 2.0 2 0 0 2 2 2 0 Small metal-binding protein ArfGap PF01412.18 ORY10325.1 - 7.9e-34 116.2 0.4 1.5e-33 115.4 0.4 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf DUF1989 PF09347.10 ORY10326.1 - 2.9e-38 131.2 0.7 5.9e-36 123.6 0.7 2.8 1 1 0 1 1 1 1 Domain of unknown function (DUF1989) ArlS_N PF18719.1 ORY10326.1 - 0.072 13.3 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 ArlS sensor domain NOG1_N PF17835.1 ORY10327.1 - 4.1e-50 169.9 0.1 1.2e-49 168.3 0.1 1.8 1 0 0 1 1 1 1 NOG1 N-terminal helical domain NOGCT PF08155.11 ORY10327.1 - 7.2e-26 89.9 2.0 7.2e-26 89.9 2.0 2.0 2 0 0 2 2 2 1 NOGCT (NUC087) domain NOG1 PF06858.14 ORY10327.1 - 2.9e-24 84.6 0.2 6e-24 83.6 0.2 1.6 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.23 ORY10327.1 - 5.4e-14 52.2 0.0 1.2e-13 51.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 ORY10327.1 - 7.4e-07 28.8 0.0 1.8e-06 27.5 0.0 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 ORY10327.1 - 0.00056 19.8 0.0 0.9 9.4 0.0 3.1 2 0 0 2 2 2 2 RsgA GTPase AAA_18 PF13238.6 ORY10327.1 - 0.063 13.8 0.0 0.28 11.7 0.0 2.2 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 ORY10327.1 - 0.2 11.7 1.8 2.3 8.3 0.0 2.7 2 1 1 3 3 3 0 Dynamin family AAA_16 PF13191.6 ORY10327.1 - 1.5 9.2 0.0 1.5 9.2 0.0 3.1 4 2 0 4 4 4 0 AAA ATPase domain Pribosyltran PF00156.27 ORY10328.1 - 1.8e-18 66.5 0.1 3e-18 65.8 0.1 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 ORY10328.1 - 0.034 13.6 0.0 0.052 13.0 0.0 1.2 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Tim17 PF02466.19 ORY10329.1 - 8.1e-26 90.6 5.7 1.1e-25 90.1 5.7 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Glyco_hydro_47 PF01532.20 ORY10330.1 - 2.5e-173 577.2 0.0 2.9e-173 577.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_76 PF03663.14 ORY10330.1 - 0.0095 15.5 0.1 1.1 8.7 0.0 2.3 2 0 0 2 2 2 2 Glycosyl hydrolase family 76 zf-RanBP PF00641.18 ORY10331.1 - 0.0059 15.9 1.2 0.0059 15.9 1.2 1.7 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others DZR PF12773.7 ORY10331.1 - 0.16 12.0 5.1 0.29 11.2 1.1 2.3 2 0 0 2 2 2 0 Double zinc ribbon Gpr1_Fun34_YaaH PF01184.19 ORY10332.1 - 7.3e-33 113.9 21.0 8.8e-33 113.7 21.0 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Cep57_CLD_2 PF14197.6 ORY10333.1 - 5.6e-05 23.1 8.7 0.56 10.3 0.2 4.3 3 1 1 4 4 4 3 Centrosome localisation domain of PPC89 UPF0242 PF06785.11 ORY10333.1 - 0.0032 17.6 1.7 0.0032 17.6 1.7 2.3 1 1 1 2 2 2 1 Uncharacterised protein family (UPF0242) N-terminus TMF_DNA_bd PF12329.8 ORY10333.1 - 0.0062 16.5 6.2 0.61 10.1 1.6 3.1 2 1 0 2 2 2 2 TATA element modulatory factor 1 DNA binding DUF4200 PF13863.6 ORY10333.1 - 0.041 14.3 5.0 2.2 8.7 0.9 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) Laminin_II PF06009.12 ORY10333.1 - 0.069 13.2 0.1 0.069 13.2 0.1 2.8 1 1 2 3 3 3 0 Laminin Domain II Spc7 PF08317.11 ORY10333.1 - 0.15 10.9 10.5 0.58 9.0 4.6 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF4094 PF13334.6 ORY10333.1 - 0.56 10.7 8.8 3.8 8.0 2.2 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4094) TMF_TATA_bd PF12325.8 ORY10333.1 - 0.57 10.4 7.4 1.4 9.1 3.1 3.2 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding DUF4618 PF15397.6 ORY10333.1 - 1.1 8.6 10.0 7.8 5.8 8.8 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) KxDL PF10241.9 ORY10333.1 - 1.5 9.2 6.1 5.2 7.4 1.4 2.8 3 0 0 3 3 3 0 Uncharacterized conserved protein DivIC PF04977.15 ORY10333.1 - 4.2 7.2 9.2 2.5 7.9 1.4 3.4 3 1 1 4 4 4 0 Septum formation initiator FAM76 PF16046.5 ORY10333.1 - 5.1 6.3 8.8 3.4 6.9 4.6 2.3 1 1 1 2 2 2 0 FAM76 protein CENP-H PF05837.12 ORY10333.1 - 6.8 7.1 10.3 3.3 8.2 3.1 3.1 1 1 1 2 2 2 0 Centromere protein H (CENP-H) His_Phos_1 PF00300.22 ORY10335.1 - 3.7e-37 127.9 0.0 4.9e-37 127.5 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) HET PF06985.11 ORY10336.1 - 7.5e-24 84.7 0.0 1.4e-23 83.9 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.7 ORY10336.1 - 2.9e-19 69.5 0.1 2.2e-05 25.0 0.0 4.9 4 1 0 5 5 5 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY10336.1 - 3.1e-12 46.7 1.7 0.0014 19.2 0.0 4.8 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 ORY10336.1 - 2.7e-11 43.4 5.7 0.13 12.8 0.1 7.1 6 1 1 7 7 7 4 Ankyrin repeat Ank_5 PF13857.6 ORY10336.1 - 5.6e-11 42.5 0.4 5.9e-06 26.4 0.0 4.5 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY10336.1 - 2.4e-10 39.7 6.2 1.3 9.8 0.0 7.5 8 0 0 8 8 8 3 Ankyrin repeat PUA_3 PF17785.1 ORY10336.1 - 0.16 11.8 0.0 0.38 10.6 0.0 1.5 1 0 0 1 1 1 0 PUA-like domain Podoplanin PF05808.11 ORY10337.1 - 0.04 14.0 1.6 0.068 13.3 1.6 1.3 1 0 0 1 1 1 0 Podoplanin GRA6 PF05084.13 ORY10337.1 - 0.041 13.8 0.1 0.056 13.4 0.1 1.2 1 0 0 1 1 1 0 Granule antigen protein (GRA6) SKG6 PF08693.10 ORY10337.1 - 0.074 12.5 6.0 0.15 11.5 6.0 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Mid2 PF04478.12 ORY10337.1 - 0.13 12.1 1.7 0.29 11.0 1.7 1.6 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor MGC-24 PF05283.11 ORY10337.1 - 1 9.8 8.6 0.95 9.9 7.3 1.6 1 1 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Cellulase PF00150.18 ORY10338.1 - 4.1e-20 72.4 4.7 8.7e-20 71.3 4.7 1.5 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF1772 PF08592.11 ORY10339.1 - 3.3e-24 85.8 1.5 4.3e-24 85.4 1.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) Acyl-CoA_dh_1 PF00441.24 ORY10339.1 - 0.033 14.4 0.4 0.044 14.0 0.4 1.2 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain DUF2976 PF11190.8 ORY10339.1 - 0.14 12.0 0.7 0.31 10.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) NmrA PF05368.13 ORY10340.1 - 3.7e-31 108.5 0.0 9.7e-31 107.1 0.0 1.6 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ORY10340.1 - 1.2e-12 48.1 0.0 1.5e-12 47.8 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 ORY10340.1 - 0.00098 18.6 0.0 0.0017 17.9 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 ORY10340.1 - 0.15 12.0 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 KR domain FAD_binding_3 PF01494.19 ORY10342.1 - 1e-14 54.6 3.4 2.8e-12 46.6 3.4 3.1 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 ORY10342.1 - 5.3e-10 39.4 1.1 0.00059 19.5 0.0 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ORY10342.1 - 7.7e-10 38.5 0.1 0.00041 19.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ORY10342.1 - 4.6e-08 32.5 1.2 2.8e-07 30.0 0.5 2.0 1 1 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 ORY10342.1 - 5.4e-07 28.7 0.2 0.00098 17.9 0.1 2.2 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_8 PF13450.6 ORY10342.1 - 1e-05 25.7 0.1 2.8e-05 24.2 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 ORY10342.1 - 3.4e-05 23.4 0.0 6e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 ORY10342.1 - 0.00012 21.3 0.1 0.0046 16.1 0.1 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 ORY10342.1 - 0.00018 20.9 0.0 0.0025 17.1 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 ORY10342.1 - 0.00047 19.3 1.0 0.17 10.9 0.1 2.6 3 0 0 3 3 3 2 Lycopene cyclase protein Pyr_redox PF00070.27 ORY10342.1 - 0.00086 19.8 0.0 0.079 13.5 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 ORY10342.1 - 0.0018 17.6 0.0 0.0042 16.4 0.0 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 ORY10342.1 - 0.0053 16.0 0.0 0.01 15.1 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Amino_oxidase PF01593.24 ORY10342.1 - 0.0066 15.8 0.0 2 7.6 0.0 2.4 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase 3HCDH_N PF02737.18 ORY10342.1 - 0.099 12.5 0.1 0.21 11.4 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.6 ORY10342.1 - 0.17 11.9 0.0 14 5.7 0.0 2.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding p450 PF00067.22 ORY10343.1 - 1.1e-59 202.4 0.0 1.5e-59 202.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 BBE PF08031.12 ORY10344.1 - 0.041 14.0 0.5 0.099 12.8 0.5 1.6 1 0 0 1 1 1 0 Berberine and berberine like Myb_DNA-binding PF00249.31 ORY10345.1 - 0.14 12.4 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain PALP PF00291.25 ORY10347.1 - 2e-65 221.1 0.3 2.6e-65 220.7 0.3 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.28 ORY10347.1 - 6.8e-11 42.5 0.0 1.8e-07 31.5 0.0 3.3 4 0 0 4 4 4 2 CBS domain SRPRB PF09439.10 ORY10350.1 - 4.9e-29 101.0 0.0 2.5e-28 98.7 0.0 1.9 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.21 ORY10350.1 - 8.1e-06 25.4 0.0 8.8e-05 22.0 0.0 2.1 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 ORY10350.1 - 3e-05 24.1 0.0 4.5e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 ORY10350.1 - 0.00074 19.9 0.2 0.0019 18.6 0.2 1.8 1 1 0 1 1 1 1 AAA ATPase domain cobW PF02492.19 ORY10350.1 - 0.0044 16.6 0.1 1 8.9 0.1 2.2 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain GTP_EFTU PF00009.27 ORY10350.1 - 0.013 15.0 0.0 0.062 12.8 0.0 2.1 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 ORY10350.1 - 0.017 15.4 0.0 0.037 14.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 ORY10350.1 - 0.026 15.0 0.1 0.19 12.2 0.1 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Roc PF08477.13 ORY10350.1 - 0.028 14.6 0.0 0.17 12.1 0.0 2.1 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 ORY10350.1 - 0.04 13.8 0.0 0.87 9.5 0.0 2.6 3 0 0 3 3 3 0 RsgA GTPase AAA_29 PF13555.6 ORY10350.1 - 0.085 12.6 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 ORY10350.1 - 0.13 12.8 0.0 0.24 11.9 0.0 1.3 1 0 0 1 1 1 0 ABC transporter Ras PF00071.22 ORY10350.1 - 0.14 11.7 0.0 0.55 9.8 0.0 1.8 1 1 0 1 1 1 0 Ras family AAA_23 PF13476.6 ORY10350.1 - 0.26 11.8 0.0 0.4 11.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain NDT80_PhoG PF05224.12 ORY10351.1 - 6.3e-39 134.1 1.1 8.9e-39 133.6 1.1 1.2 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family ORC4_C PF14629.6 ORY10354.1 - 1.4e-56 191.4 0.0 2.2e-56 190.6 0.0 1.4 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.6 ORY10354.1 - 1.8e-17 64.3 0.0 4.5e-17 62.9 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 ORY10354.1 - 1.8e-08 34.7 0.0 8.1e-08 32.6 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA PF00004.29 ORY10354.1 - 8.3e-07 29.5 0.0 2.3e-06 28.0 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 ORY10354.1 - 4.3e-06 26.8 0.2 4.1e-05 23.6 0.2 2.2 1 1 0 1 1 1 1 NACHT domain DUF815 PF05673.13 ORY10354.1 - 1.5e-05 24.3 0.0 2.5e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) KAP_NTPase PF07693.14 ORY10354.1 - 0.00034 20.0 0.0 0.00062 19.1 0.0 1.4 1 0 0 1 1 1 1 KAP family P-loop domain ATPase_2 PF01637.18 ORY10354.1 - 0.0035 17.3 0.0 0.007 16.3 0.0 1.5 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_7 PF12775.7 ORY10354.1 - 0.0075 15.8 0.0 0.015 14.8 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region PIF1 PF05970.14 ORY10354.1 - 0.011 14.9 0.1 0.032 13.4 0.0 1.7 2 0 0 2 2 2 0 PIF1-like helicase T2SSE PF00437.20 ORY10354.1 - 0.013 14.6 0.1 0.026 13.6 0.1 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF2791 PF10923.8 ORY10354.1 - 0.019 13.9 0.0 0.032 13.1 0.0 1.3 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) ATP-synt_ab PF00006.25 ORY10354.1 - 0.029 14.0 0.1 0.1 12.3 0.1 2.0 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain NB-ARC PF00931.22 ORY10354.1 - 0.035 13.3 0.1 0.069 12.3 0.1 1.4 1 0 0 1 1 1 0 NB-ARC domain DUF2075 PF09848.9 ORY10354.1 - 0.039 13.2 0.0 0.07 12.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 ORY10354.1 - 0.04 14.3 0.0 0.13 12.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 ORY10354.1 - 0.042 13.9 0.0 0.093 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 ORY10354.1 - 0.046 13.3 0.1 0.46 10.1 0.0 2.1 1 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain TniB PF05621.11 ORY10354.1 - 0.099 12.0 0.1 1.6 8.1 0.1 2.2 1 1 0 1 1 1 0 Bacterial TniB protein DUF1996 PF09362.10 ORY10356.1 - 2.1e-80 270.1 4.7 3.3e-80 269.4 1.7 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1996) DNase_NucA_NucB PF14040.6 ORY10357.1 - 0.00054 20.3 0.1 0.0019 18.5 0.1 2.0 1 1 0 1 1 1 1 Deoxyribonuclease NucA/NucB LysM PF01476.20 ORY10358.1 - 0.0035 17.4 0.0 0.005 16.9 0.0 1.2 1 0 0 1 1 1 1 LysM domain 4_1_CTD PF05902.13 ORY10359.1 - 0.074 13.1 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 4.1 protein C-terminal domain (CTD) Abhydrolase_6 PF12697.7 ORY10361.1 - 8e-12 46.2 0.4 1.4e-11 45.4 0.4 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORY10361.1 - 1.2e-06 28.0 0.0 1.8e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ORY10361.1 - 0.00038 20.2 0.0 0.0025 17.5 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Ser_hydrolase PF06821.13 ORY10361.1 - 0.015 15.2 2.0 0.72 9.7 0.0 2.3 2 0 0 2 2 2 0 Serine hydrolase p450 PF00067.22 ORY10363.1 - 6.4e-26 91.1 0.2 1.9e-25 89.5 0.2 1.7 2 1 0 2 2 2 1 Cytochrome P450 MFS_1 PF07690.16 ORY10364.1 - 1.6e-39 135.8 50.0 1.6e-39 135.8 50.0 2.9 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 ORY10364.1 - 8.5e-07 27.8 24.5 1.1e-06 27.4 24.5 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF4203 PF13886.6 ORY10364.1 - 0.00085 19.0 9.5 0.00085 19.0 9.5 4.3 4 2 2 6 6 6 1 Domain of unknown function (DUF4203) MASE5 PF17178.4 ORY10364.1 - 0.12 12.2 11.0 0.31 10.8 8.4 2.5 2 0 0 2 2 2 0 Membrane-associated sensor MPC PF03650.13 ORY10364.1 - 0.16 12.1 1.1 0.51 10.5 0.1 2.2 2 0 0 2 2 2 0 Mitochondrial pyruvate carriers Abhydrolase_3 PF07859.13 ORY10365.1 - 5.9e-45 153.7 0.0 7.2e-45 153.4 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 ORY10365.1 - 1.8e-08 33.7 1.6 6.9e-08 31.8 1.6 1.7 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.7 ORY10365.1 - 0.00052 20.7 0.7 0.00082 20.0 0.7 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family TPP_enzyme_N PF02776.18 ORY10366.1 - 3.7e-44 150.3 0.0 1.4e-43 148.4 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 ORY10366.1 - 7e-28 97.1 0.0 1.2e-27 96.3 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 ORY10366.1 - 3.3e-20 72.4 0.1 8.1e-20 71.2 0.1 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain CO_dh PF02552.16 ORY10366.1 - 0.22 11.3 0.0 0.39 10.5 0.0 1.3 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit TGT PF01702.18 ORY10368.1 - 1.6e-138 461.7 0.0 1.9e-138 461.4 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase F-box PF00646.33 ORY10370.1 - 0.00046 20.0 0.4 0.0011 18.8 0.4 1.6 1 0 0 1 1 1 1 F-box domain Glyco_hydro_16 PF00722.21 ORY10371.1 - 9.3e-08 31.7 0.1 1.5e-07 31.0 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Polysacc_deac_1 PF01522.21 ORY10372.1 - 5.5e-13 48.9 0.0 9.4e-13 48.2 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase R3H PF01424.22 ORY10378.1 - 1.7e-14 53.5 0.1 3e-14 52.8 0.1 1.4 1 0 0 1 1 1 1 R3H domain Aa_trans PF01490.18 ORY10379.1 - 2.9e-50 171.2 37.7 3.3e-50 171.0 37.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein UbiA PF01040.18 ORY10381.1 - 1.5e-07 31.0 0.7 2.8e-07 30.1 0.7 1.6 1 1 0 1 1 1 1 UbiA prenyltransferase family NACHT PF05729.12 ORY10382.1 - 1.3e-08 34.9 0.2 1e-07 32.0 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 ORY10382.1 - 5.9e-06 26.8 0.2 5.3e-05 23.7 0.1 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 ORY10382.1 - 0.0019 18.5 0.0 0.015 15.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain DUF676 PF05057.14 ORY10383.1 - 3.2e-42 144.5 0.0 1.7e-28 99.7 0.0 3.3 2 1 1 3 3 3 3 Putative serine esterase (DUF676) Not1 PF04054.15 ORY10386.1 - 1.2e-127 425.9 0.2 1.2e-127 425.9 0.2 2.1 2 0 0 2 2 2 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 ORY10386.1 - 1.4e-90 302.6 0.3 3.4e-90 301.4 0.3 1.7 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain DUF3819 PF12842.7 ORY10386.1 - 2.8e-47 160.3 5.8 9.5e-47 158.6 5.8 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) CNOT1_TTP_bind PF16417.5 ORY10386.1 - 1.3e-45 154.9 0.0 5.1e-45 153.0 0.0 2.0 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 TTP binding domain CNOT1_HEAT PF16418.5 ORY10386.1 - 5.4e-32 111.0 1.7 8.4e-32 110.3 0.4 2.1 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 HEAT repeat HEAT_2 PF13646.6 ORY10386.1 - 0.082 13.3 0.5 1.1 9.7 0.1 3.1 2 1 0 2 2 2 0 HEAT repeats DUF4508 PF14969.6 ORY10386.1 - 0.14 12.4 0.1 0.74 10.1 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4508) FCH PF00611.23 ORY10387.1 - 8.5e-14 51.6 0.0 2.5e-13 50.1 0.0 1.9 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.6 ORY10387.1 - 2.6e-12 46.4 0.1 4.9e-12 45.5 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 ORY10387.1 - 3.8e-12 45.6 0.0 8.3e-12 44.5 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 ORY10387.1 - 1.4e-10 40.7 0.0 1.1e-09 37.8 0.0 2.3 2 0 0 2 2 2 1 Variant SH3 domain PP_kinase_N PF13089.6 ORY10387.1 - 0.16 12.3 1.5 0.41 11.0 0.0 2.5 3 0 0 3 3 3 0 Polyphosphate kinase N-terminal domain DUF1899 PF08953.11 ORY10389.1 - 0.14 12.0 0.0 11 6.0 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1899) BTB PF00651.31 ORY10390.1 - 0.017 15.3 0.0 0.032 14.5 0.0 1.4 1 0 0 1 1 1 0 BTB/POZ domain Epimerase PF01370.21 ORY10391.1 - 1.3e-12 47.7 0.0 2.6e-12 46.7 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 ORY10391.1 - 3.7e-12 45.8 0.0 5.3e-12 45.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 ORY10391.1 - 7.1e-09 35.5 0.0 1.3e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 ORY10391.1 - 9.5e-08 32.1 0.0 1.4e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 ORY10391.1 - 3.6e-06 26.7 0.0 6.1e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.12 ORY10391.1 - 0.00022 20.5 0.0 0.11 11.6 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.15 ORY10391.1 - 0.007 15.5 0.0 0.0098 15.0 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.25 ORY10391.1 - 0.15 11.5 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase DAGK_cat PF00781.24 ORY10392.1 - 4.4e-11 42.5 0.0 6.2e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain XPG_I_2 PF12813.7 ORY10394.1 - 8e-37 127.1 0.0 1.8e-36 125.9 0.0 1.6 2 0 0 2 2 2 1 XPG domain containing XPG_I PF00867.18 ORY10394.1 - 0.00026 21.3 0.0 0.00056 20.2 0.0 1.5 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 ORY10394.1 - 0.0021 18.5 0.0 0.0044 17.5 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain 5_3_exonuc_N PF02739.16 ORY10394.1 - 0.031 14.2 0.0 0.12 12.3 0.0 2.0 1 1 0 1 1 1 0 5'-3' exonuclease, N-terminal resolvase-like domain PGM_PMM_I PF02878.16 ORY10395.1 - 3e-32 111.2 0.0 4.5e-32 110.6 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 ORY10395.1 - 2.7e-25 88.8 0.0 4.7e-25 88.0 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 ORY10395.1 - 2.6e-15 56.9 0.1 5.7e-15 55.8 0.1 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 ORY10395.1 - 6.3e-08 32.7 0.0 1.4e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain TFIIB PF00382.19 ORY10397.1 - 1.1e-33 115.0 0.3 2.6e-18 65.8 0.1 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 ORY10397.1 - 5.6e-14 51.4 1.1 9.9e-14 50.6 1.1 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding RB_B PF01857.20 ORY10397.1 - 0.0001 22.3 0.1 0.00023 21.2 0.1 1.6 2 0 0 2 2 2 1 Retinoblastoma-associated protein B domain zf-ribbon_3 PF13248.6 ORY10397.1 - 0.062 12.7 0.8 0.51 9.8 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Cyclin_N PF00134.23 ORY10397.1 - 0.071 12.9 0.1 0.15 11.8 0.1 1.5 1 0 0 1 1 1 0 Cyclin, N-terminal domain ATP_sub_h PF10775.9 ORY10398.1 - 1.6e-25 88.8 1.2 4e-25 87.6 1.2 1.7 1 0 0 1 1 1 1 ATP synthase complex subunit h DUF1765 PF08578.10 ORY10400.1 - 2.1e-43 147.7 4.0 4e-43 146.9 4.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) ADH_N PF08240.12 ORY10401.1 - 1.2e-21 76.6 1.2 2.6e-21 75.5 0.9 1.7 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORY10401.1 - 1.5e-21 76.8 0.2 3.2e-21 75.7 0.2 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 ORY10401.1 - 5e-07 29.4 0.4 8.5e-07 28.7 0.4 1.4 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 ORY10401.1 - 0.0054 17.8 0.0 0.012 16.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Zn_clus PF00172.18 ORY10403.1 - 5.4e-09 36.0 10.7 1.1e-08 35.0 10.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 ORY10403.1 - 1.5e-06 27.3 1.6 1.2e-05 24.3 0.2 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Lipase_GDSL_2 PF13472.6 ORY10404.1 - 2.4e-11 44.3 0.3 3.3e-11 43.9 0.3 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 ORY10404.1 - 1.1e-06 28.7 0.1 1.4e-06 28.5 0.1 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase ALGX PF16822.5 ORY10404.1 - 0.0021 17.8 0.1 0.72 9.5 0.0 2.2 2 0 0 2 2 2 2 SGNH hydrolase-like domain, acetyltransferase AlgX Rtf2 PF04641.12 ORY10405.1 - 6.3e-59 199.5 13.8 1.4e-58 198.4 13.8 1.5 1 1 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.8 ORY10405.1 - 7.1e-05 22.6 0.0 0.004 16.9 0.0 2.5 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit CSD PF00313.22 ORY10405.1 - 0.081 12.8 1.8 5.5 6.9 0.2 3.1 3 0 0 3 3 3 0 'Cold-shock' DNA-binding domain zf-NOSIP PF15906.5 ORY10405.1 - 0.12 12.5 0.0 0.29 11.3 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein FAM176 PF14851.6 ORY10405.1 - 2 8.1 8.0 4.4 7.0 8.0 1.6 1 0 0 1 1 1 0 FAM176 family PPR_2 PF13041.6 ORY10406.1 - 3.1e-17 62.5 0.0 1.9e-15 56.8 0.0 2.8 2 0 0 2 2 2 1 PPR repeat family PPR_3 PF13812.6 ORY10406.1 - 0.0001 22.3 0.1 1.9 8.6 0.0 3.6 3 1 1 4 4 4 3 Pentatricopeptide repeat domain PPR PF01535.20 ORY10406.1 - 0.00022 21.3 0.2 0.089 13.1 0.0 3.7 3 0 0 3 3 3 1 PPR repeat PPR_1 PF12854.7 ORY10406.1 - 0.035 13.8 0.0 0.85 9.4 0.0 2.7 2 0 0 2 2 2 0 PPR repeat Defensin_5 PF18251.1 ORY10408.1 - 3.2 7.9 10.5 0.86 9.7 7.1 1.8 2 0 0 2 2 2 0 Fungal defensin Copsin Phos_pyr_kin PF08543.12 ORY10411.1 - 1.8e-81 273.2 1.7 1.8e-81 273.2 1.7 1.8 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase DEAD PF00270.29 ORY10411.1 - 2.9e-49 167.2 0.0 1.5e-48 164.9 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase TENA_THI-4 PF03070.16 ORY10411.1 - 4.8e-36 124.6 0.7 6.7e-23 81.6 0.1 2.3 2 0 0 2 2 2 2 TENA/THI-4/PQQC family Helicase_C PF00271.31 ORY10411.1 - 1.4e-29 102.7 0.0 4e-29 101.2 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PfkB PF00294.24 ORY10411.1 - 9.9e-08 31.6 0.2 2.1e-07 30.6 0.2 1.5 1 0 0 1 1 1 1 pfkB family carbohydrate kinase ResIII PF04851.15 ORY10411.1 - 0.00054 20.0 0.0 0.0014 18.6 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF5335 PF17269.2 ORY10411.1 - 0.036 13.9 0.1 0.07 13.0 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5335) AAA_19 PF13245.6 ORY10411.1 - 0.15 12.4 0.0 26 5.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain PAS_10 PF13596.6 ORY10411.1 - 0.17 12.5 0.3 0.89 10.2 0.1 2.2 2 0 0 2 2 2 0 PAS domain Carb_kinase PF01256.17 ORY10411.1 - 0.45 10.0 0.0 0.45 10.0 0.0 2.3 3 0 0 3 3 3 0 Carbohydrate kinase LRR_4 PF12799.7 ORY10412.1 - 0.31 11.5 2.8 1.4e+02 3.1 0.0 4.8 3 2 1 4 4 4 0 Leucine Rich repeats (2 copies) Rad9 PF04139.13 ORY10413.1 - 8e-50 169.6 0.0 1e-49 169.2 0.0 1.1 1 0 0 1 1 1 1 Rad9 RCC1 PF00415.18 ORY10414.1 - 8.5e-31 106.3 22.4 2.1e-09 37.9 0.1 7.3 8 2 0 8 8 8 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 ORY10414.1 - 6.5e-17 60.9 29.7 6.5e-06 25.8 1.3 6.3 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat Ribosomal_S9 PF00380.19 ORY10415.1 - 3e-33 114.9 0.2 3.3e-33 114.8 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 ChAPs PF09295.10 ORY10416.1 - 7.9e-154 512.4 0.0 1e-153 512.1 0.0 1.1 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_19 PF14559.6 ORY10416.1 - 2.4e-07 31.2 0.8 0.0045 17.5 0.1 3.6 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 ORY10416.1 - 5.1e-07 30.0 2.9 2 9.5 0.0 4.9 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 ORY10416.1 - 1.5e-06 27.9 2.1 0.037 14.1 0.1 4.4 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 ORY10416.1 - 0.00054 19.7 0.9 0.78 9.7 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY10416.1 - 0.0013 18.9 1.2 1.9 8.8 0.0 3.4 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 ORY10416.1 - 0.0026 17.9 0.1 2 8.7 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 ORY10416.1 - 0.011 15.9 0.0 1 9.8 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 ORY10416.1 - 0.018 15.7 0.4 1e+02 3.9 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_15 PF13429.6 ORY10416.1 - 0.02 14.1 1.1 1.1 8.4 0.1 2.5 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 ORY10416.1 - 0.18 11.9 2.5 29 5.0 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 ORY10416.1 - 1.7 9.0 7.1 55 4.2 0.0 4.6 3 1 2 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.6 ORY10417.1 - 0.037 13.7 0.1 1.6 8.5 0.3 2.7 2 0 0 2 2 2 0 TPR repeat TPR_17 PF13431.6 ORY10417.1 - 0.11 13.0 2.5 0.66 10.5 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF1279 PF06916.13 ORY10421.1 - 8.6e-22 77.5 0.0 1.2e-21 77.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) Vps35 PF03635.17 ORY10422.1 - 0 1043.6 1.9 0 1043.4 1.9 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 Pro_3_hydrox_C PF05373.11 ORY10422.1 - 0.063 13.4 0.2 8 6.6 0.0 3.0 3 0 0 3 3 3 0 L-proline 3-hydroxylase, C-terminal Pkinase PF00069.25 ORY10424.1 - 6.6e-35 120.8 0.0 9e-35 120.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY10424.1 - 6e-18 65.1 0.0 8e-18 64.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Fasciclin PF02469.22 ORY10425.1 - 3.2e-53 179.3 3.6 2e-29 102.4 0.1 2.3 2 0 0 2 2 2 2 Fasciclin domain XPC-binding PF09280.11 ORY10425.1 - 0.024 14.4 0.4 3.3 7.5 0.2 2.7 2 1 0 2 2 2 0 XPC-binding domain DASH_Duo1 PF08651.10 ORY10426.1 - 0.065 13.0 0.2 0.18 11.6 0.2 1.7 1 0 0 1 1 1 0 DASH complex subunit Duo1 DHquinase_I PF01487.15 ORY10427.1 - 5.6e-23 82.4 0.0 1.1e-22 81.5 0.0 1.3 1 0 0 1 1 1 1 Type I 3-dehydroquinase Shikimate_dh_N PF08501.11 ORY10427.1 - 3.7e-19 68.7 0.1 7.1e-19 67.8 0.1 1.5 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 ORY10427.1 - 5e-10 39.0 0.2 9.8e-10 38.0 0.2 1.5 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain SKI PF01202.22 ORY10427.1 - 2.6e-09 37.4 0.0 4.7e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 Shikimate kinase Shikimate_DH PF01488.20 ORY10427.1 - 3e-07 30.6 0.0 8.7e-07 29.1 0.0 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 ORY10427.1 - 0.012 16.2 0.0 0.028 15.0 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 ORY10427.1 - 0.12 12.6 0.0 0.38 11.0 0.0 1.8 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain AAA_16 PF13191.6 ORY10427.1 - 0.27 11.6 1.6 0.66 10.3 0.6 2.2 2 2 0 2 2 2 0 AAA ATPase domain Fungal_trans PF04082.18 ORY10428.1 - 3.3e-06 26.3 0.0 1.1e-05 24.6 0.0 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY10428.1 - 4.5e-06 26.7 11.2 7.1e-06 26.0 11.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AP_endonuc_2 PF01261.24 ORY10429.1 - 1.1e-33 116.5 0.1 2.9e-33 115.1 0.0 1.6 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel GFO_IDH_MocA PF01408.22 ORY10430.1 - 8.1e-27 94.4 0.0 1.2e-26 93.9 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 ORY10430.1 - 1.1e-11 44.8 0.0 2e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Semialdhyde_dh PF01118.24 ORY10430.1 - 0.039 14.4 0.0 0.083 13.3 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 ORY10430.1 - 0.06 13.5 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Sugar_tr PF00083.24 ORY10431.1 - 6.8e-137 457.0 21.5 7.9e-137 456.8 21.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY10431.1 - 5.6e-21 74.9 44.0 6.8e-20 71.3 42.6 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Shikimate_dh_N PF08501.11 ORY10432.1 - 1.4e-20 73.3 0.0 2.7e-20 72.4 0.0 1.5 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 ORY10432.1 - 2.4e-05 24.0 0.0 4.9e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 ORY10432.1 - 0.024 14.9 0.0 0.038 14.3 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 ORY10432.1 - 0.063 13.3 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Inositol_P PF00459.25 ORY10433.1 - 5.7e-79 265.4 0.0 6.4e-79 265.3 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family DHquinase_II PF01220.19 ORY10434.1 - 5.3e-60 201.1 0.0 6e-60 200.9 0.0 1.0 1 0 0 1 1 1 1 Dehydroquinase class II AurF PF11583.8 ORY10434.1 - 0.052 12.8 0.2 0.061 12.6 0.2 1.1 1 0 0 1 1 1 0 P-aminobenzoate N-oxygenase AurF Dioxygenase_C PF00775.21 ORY10436.1 - 1.6e-42 145.0 0.0 2.1e-42 144.6 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 ORY10436.1 - 3e-31 107.1 0.0 6.9e-31 105.9 0.0 1.7 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 ORY10436.1 - 0.025 14.9 0.0 0.086 13.1 0.0 1.8 1 1 0 1 1 1 0 Carboxypeptidase regulatory-like domain DUF3445 PF11927.8 ORY10437.1 - 1.2e-74 250.8 0.0 1.4e-74 250.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) DUF4559 PF15112.6 ORY10437.1 - 0.15 11.7 0.1 0.21 11.2 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) DNA_pol_A_exo1 PF01612.20 ORY10439.1 - 3.3e-10 40.0 0.0 5.2e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease DUF1772 PF08592.11 ORY10456.1 - 1.1e-08 35.5 1.1 1.3e-08 35.2 1.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) YusW PF14039.6 ORY10456.1 - 0.17 12.4 0.2 0.28 11.7 0.2 1.3 1 0 0 1 1 1 0 YusW-like protein Chromate_transp PF02417.15 ORY10456.1 - 0.2 11.8 5.7 0.15 12.2 1.9 2.0 2 0 0 2 2 2 0 Chromate transporter adh_short_C2 PF13561.6 ORY10457.1 - 8.5e-37 126.9 6.2 2.9e-36 125.2 6.2 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY10457.1 - 9.6e-29 100.2 2.3 1.3e-28 99.8 2.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORY10457.1 - 5e-08 33.1 0.8 3.7e-07 30.2 0.4 2.0 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 ORY10457.1 - 0.04 13.0 0.2 0.072 12.2 0.1 1.4 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Cofilin_ADF PF00241.20 ORY10458.1 - 3.6e-34 117.2 0.0 1.2e-19 70.2 0.0 2.1 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein Mito_carr PF00153.27 ORY10459.1 - 6.1e-64 212.0 2.0 2.6e-23 81.8 0.0 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 ORY10459.1 - 0.035 13.3 0.1 0.073 12.2 0.1 1.6 1 1 0 1 1 1 0 Gammaproteobacterial serine protease CorA PF01544.18 ORY10460.1 - 1.5e-10 40.9 0.2 2.4e-10 40.2 0.2 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Glyco_hydro_43 PF04616.14 ORY10461.1 - 3.7e-12 46.1 6.0 5.9e-12 45.5 6.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GMC_oxred_N PF00732.19 ORY10462.1 - 5.8e-12 45.6 0.0 1.1e-11 44.7 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 ORY10462.1 - 2.2e-09 38.0 0.3 5e-09 36.8 0.3 1.6 1 0 0 1 1 1 1 GMC oxidoreductase Abhydrolase_6 PF12697.7 ORY10462.1 - 0.00033 21.3 5.5 0.00038 21.1 0.2 3.0 2 1 0 2 2 2 1 Alpha/beta hydrolase family FAD_binding_2 PF00890.24 ORY10462.1 - 0.00047 19.4 2.3 0.0008 18.6 2.3 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 ORY10462.1 - 0.0075 15.5 0.1 0.012 14.9 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORY10462.1 - 0.02 15.1 1.9 0.068 13.4 1.9 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 ORY10462.1 - 0.041 13.2 3.6 0.06 12.7 3.6 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Hydrolase_4 PF12146.8 ORY10462.1 - 0.12 11.6 0.0 0.43 9.8 0.0 1.9 2 0 0 2 2 2 0 Serine aminopeptidase, S33 GIDA PF01134.22 ORY10462.1 - 0.13 11.4 0.1 0.21 10.7 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A zf-C3HC4 PF00097.25 ORY10463.1 - 8.1e-08 32.0 7.0 8.1e-08 32.0 7.0 5.1 5 2 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORY10463.1 - 1.7e-06 28.3 7.3 1.7e-06 28.3 7.3 4.5 4 1 0 4 4 4 1 Ring finger domain zf-RING_UBOX PF13445.6 ORY10463.1 - 2.9e-06 27.2 6.2 2.9e-06 27.2 6.2 3.6 4 1 0 4 4 4 1 RING-type zinc-finger zf-RING_6 PF14835.6 ORY10463.1 - 4e-06 26.6 0.6 4e-06 26.6 0.6 2.8 3 0 0 3 3 3 1 zf-RING of BARD1-type protein zf-C3HC4_2 PF13923.6 ORY10463.1 - 6.9e-06 25.8 8.3 6.9e-06 25.8 8.3 4.6 5 2 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) ZZ PF00569.17 ORY10463.1 - 3.8e-05 23.4 5.8 3.8e-05 23.4 5.8 4.0 4 0 0 4 4 4 2 Zinc finger, ZZ type zf-C3HC4_4 PF15227.6 ORY10463.1 - 9.8e-05 22.4 8.8 9.8e-05 22.4 8.8 4.0 5 1 1 6 6 6 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 ORY10463.1 - 0.00057 19.8 6.1 0.00057 19.8 6.1 5.3 6 0 0 6 6 6 1 zinc-RING finger domain SH3_9 PF14604.6 ORY10463.1 - 0.025 14.5 0.2 0.057 13.3 0.2 1.6 1 0 0 1 1 1 0 Variant SH3 domain Glyco_hydro_47 PF01532.20 ORY10464.1 - 9.1e-171 568.8 0.0 1e-170 568.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 TAtT PF16811.5 ORY10464.1 - 0.15 11.4 0.0 0.3 10.4 0.0 1.4 1 0 0 1 1 1 0 TRAP transporter T-component Med20 PF08612.11 ORY10465.1 - 1.7e-14 53.7 0.0 1.8e-14 53.7 0.0 1.2 1 0 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex RRM_1 PF00076.22 ORY10466.1 - 2.1e-38 130.0 0.0 1.4e-11 44.0 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 ORY10466.1 - 2.4e-13 49.7 0.0 0.0063 16.4 0.0 4.3 4 0 0 4 4 4 4 Occluded RNA-recognition motif RRM PF10378.9 ORY10466.1 - 4.5e-07 29.5 6.8 4.5e-07 29.5 6.8 4.4 4 2 1 5 5 5 1 Putative RRM domain DUF4523 PF15023.6 ORY10466.1 - 1.5e-05 24.8 0.0 0.025 14.4 0.0 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF4523) RRM_7 PF16367.5 ORY10466.1 - 2.3e-05 24.4 0.0 0.024 14.8 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif RRM_3 PF08777.11 ORY10466.1 - 0.0088 16.1 3.8 0.4 10.8 0.1 3.2 4 0 0 4 4 4 1 RNA binding motif RNA_bind PF08675.11 ORY10466.1 - 0.12 12.4 0.4 0.58 10.2 0.0 2.3 3 0 0 3 3 3 0 RNA binding domain Alg6_Alg8 PF03155.15 ORY10467.1 - 3.6e-175 583.6 30.0 4.5e-175 583.3 30.0 1.1 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family WAC_Acf1_DNA_bd PF10537.9 ORY10467.1 - 1.3e-38 131.6 4.2 3.5e-38 130.2 0.3 3.0 2 0 0 2 2 2 1 ATP-utilising chromatin assembly and remodelling N-terminal WSD PF15613.6 ORY10467.1 - 3.4e-19 69.1 0.1 3.4e-19 69.1 0.1 2.8 2 0 0 2 2 2 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DDT PF02791.17 ORY10467.1 - 8.3e-13 48.4 0.1 1.9e-12 47.3 0.1 1.7 1 0 0 1 1 1 1 DDT domain Glypican PF01153.19 ORY10467.1 - 0.77 8.5 5.4 1.2 7.8 5.4 1.2 1 0 0 1 1 1 0 Glypican CRA PF06589.11 ORY10467.1 - 4.1 7.5 11.7 11 6.1 11.7 1.8 1 0 0 1 1 1 0 Circumsporozoite-related antigen (CRA) CDC45 PF02724.14 ORY10467.1 - 8.6 4.5 14.1 18 3.5 14.1 1.4 1 0 0 1 1 1 0 CDC45-like protein SCA7 PF08313.12 ORY10468.1 - 2.1e-30 104.4 0.1 2.1e-30 104.4 0.1 1.9 2 0 0 2 2 2 1 SCA7, zinc-binding domain VIR_N PF15912.5 ORY10468.1 - 0.0012 18.5 2.3 0.0025 17.4 2.3 1.5 1 0 0 1 1 1 1 Virilizer, N-terminal DUF2052 PF09747.9 ORY10468.1 - 0.98 9.5 8.5 5.4 7.1 6.2 2.1 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) CDC45 PF02724.14 ORY10468.1 - 1.6 7.0 5.8 2 6.6 5.8 1.1 1 0 0 1 1 1 0 CDC45-like protein CW_binding_1 PF01473.20 ORY10469.1 - 0.32 11.4 0.3 0.32 11.4 0.3 2.7 3 0 0 3 3 3 0 Putative cell wall binding repeat APH PF01636.23 ORY10470.1 - 3.6e-14 53.3 0.0 7.6e-14 52.2 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 ORY10470.1 - 1.9e-06 27.7 0.1 2.5e-06 27.2 0.1 1.4 1 1 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.11 ORY10470.1 - 0.0003 19.8 0.1 0.00076 18.4 0.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1679) Fructosamin_kin PF03881.14 ORY10470.1 - 0.0017 17.6 0.0 0.0098 15.1 0.0 1.8 1 1 0 1 1 1 1 Fructosamine kinase EcKinase PF02958.20 ORY10470.1 - 0.014 14.7 0.1 0.03 13.6 0.0 1.7 2 0 0 2 2 2 0 Ecdysteroid kinase Zn_clus PF00172.18 ORY10471.1 - 1.8e-05 24.8 9.4 3.1e-05 24.0 9.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 ORY10472.1 - 2e-41 142.1 46.0 2e-41 142.1 46.0 1.8 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 ORY10472.1 - 7.9e-18 64.2 11.4 7.9e-18 64.2 11.4 1.4 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 ORY10472.1 - 6.2e-11 41.8 15.6 6.2e-11 41.8 15.6 2.9 3 0 0 3 3 3 1 Sugar (and other) transporter Glyco_hydro_17 PF00332.18 ORY10474.1 - 3.4e-06 26.9 0.2 3.4e-06 26.9 0.2 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 17 Glyco_hydro_53 PF07745.13 ORY10474.1 - 3e-05 23.2 0.1 4.4e-05 22.6 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 ILVD_EDD PF00920.21 ORY10475.1 - 7.4e-214 711.1 0.1 8.4e-214 711.0 0.1 1.0 1 0 0 1 1 1 1 Dehydratase family 5_nucleotid_C PF02872.18 ORY10475.1 - 0.011 15.9 0.0 0.097 12.9 0.0 2.3 2 0 0 2 2 2 0 5'-nucleotidase, C-terminal domain PRiA4_ORF3 PF07929.11 ORY10476.1 - 1.4e-07 31.3 0.0 2.5e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Plasmid pRiA4b ORF-3-like protein Zn_clus PF00172.18 ORY10477.1 - 0.00091 19.3 13.0 0.0016 18.5 13.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ORY10477.1 - 0.0012 17.9 0.2 0.002 17.2 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.18 ORY10478.1 - 9.6e-17 60.9 0.2 1.6e-16 60.2 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY10478.1 - 1e-10 41.5 6.2 2.3e-10 40.4 6.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 ORY10479.1 - 1.3e-07 30.8 32.9 1.3e-07 30.8 32.9 3.0 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 ORY10479.1 - 0.011 15.4 6.6 0.011 15.4 6.6 2.0 2 0 0 2 2 2 0 Ion channel regulatory protein UNC-93 VIT1 PF01988.19 ORY10479.1 - 0.013 15.3 0.2 0.013 15.3 0.2 3.0 3 1 0 3 3 3 0 VIT family DIOX_N PF14226.6 ORY10480.1 - 1.9e-29 102.8 0.0 2.7e-29 102.3 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 ORY10480.1 - 1.5e-23 83.2 0.0 2.8e-23 82.3 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Polysacc_deac_1 PF01522.21 ORY10481.1 - 2.7e-19 69.3 0.0 4.5e-19 68.6 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 ORY10481.1 - 9.6e-13 48.3 0.5 1.9e-12 47.3 0.5 1.6 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) Glyco_hydro_57 PF03065.15 ORY10481.1 - 3.3e-05 23.2 0.3 6.1e-05 22.4 0.1 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 57 DUF2194 PF09960.9 ORY10481.1 - 0.0014 17.1 0.1 0.0041 15.6 0.1 1.6 1 1 0 2 2 2 1 Uncharacterised protein conserved in bacteria (DUF2194) DUF4023 PF13215.6 ORY10481.1 - 0.02 14.9 1.2 0.065 13.3 0.2 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF4023) DUF3674 PF12426.8 ORY10481.1 - 0.078 13.0 1.9 0.22 11.6 1.9 1.7 1 0 0 1 1 1 0 RNA dependent RNA polymerase AAT PF03417.16 ORY10482.1 - 5.6e-30 104.7 0.0 7.3e-30 104.3 0.0 1.1 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase CBFD_NFYB_HMF PF00808.23 ORY10482.1 - 0.12 12.6 0.1 4.3 7.7 0.1 2.5 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Kelch_6 PF13964.6 ORY10483.1 - 0.051 13.9 0.5 13 6.2 0.1 3.0 2 1 1 3 3 3 0 Kelch motif AA_permease PF00324.21 ORY10484.1 - 3.6e-40 138.0 43.5 2.8e-39 135.0 43.5 2.1 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ORY10484.1 - 4.7e-28 98.2 30.5 5.9e-28 97.8 30.5 1.1 1 0 0 1 1 1 1 Amino acid permease DUF21 PF01595.20 ORY10484.1 - 0.16 11.7 4.3 17 5.1 4.3 2.7 1 1 0 1 1 1 0 Cyclin M transmembrane N-terminal domain Cerato-platanin PF07249.12 ORY10485.1 - 7.3e-58 193.9 5.7 8.7e-58 193.6 5.7 1.1 1 0 0 1 1 1 1 Cerato-platanin RHS_repeat PF05593.14 ORY10485.1 - 0.0041 17.6 0.4 0.011 16.2 0.4 1.7 1 0 0 1 1 1 1 RHS Repeat Copper-bind PF00127.20 ORY10486.1 - 6.1e-05 23.4 0.3 0.00014 22.2 0.3 1.6 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Cu_bind_like PF02298.17 ORY10486.1 - 0.045 13.8 0.3 0.2 11.7 0.3 1.9 1 1 0 1 1 1 0 Plastocyanin-like domain Bac_rhamnosid_N PF08531.10 ORY10487.1 - 3.4e-44 150.7 0.0 5.5e-44 150.0 0.0 1.3 1 0 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain Bac_rhamnosid6H PF17389.2 ORY10487.1 - 3.3e-34 118.7 0.0 3.6e-18 65.9 0.0 4.2 1 1 1 2 2 2 2 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid PF05592.11 ORY10487.1 - 2.4e-14 53.1 0.0 6.1e-14 51.8 0.0 1.7 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase concanavalin-like domain DUF3654 PF12376.8 ORY10490.1 - 1.2 9.3 5.4 2.1 8.5 5.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3654) SLAC1 PF03595.17 ORY10491.1 - 1.6e-30 106.5 30.8 7.1e-15 55.1 16.5 2.9 1 1 1 2 2 2 2 Voltage-dependent anion channel ketoacyl-synt PF00109.26 ORY10493.1 - 4e-83 278.9 0.0 1e-82 277.6 0.0 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain SAT PF16073.5 ORY10493.1 - 2.1e-77 260.1 0.0 3.2e-76 256.2 0.0 2.6 2 1 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Acyl_transf_1 PF00698.21 ORY10493.1 - 8.6e-44 150.3 0.0 1.4e-43 149.6 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain PP-binding PF00550.25 ORY10493.1 - 2.4e-33 114.3 9.0 9.9e-13 48.2 0.1 4.0 3 0 0 3 3 3 3 Phosphopantetheine attachment site Ketoacyl-synt_C PF02801.22 ORY10493.1 - 4.9e-33 113.6 0.2 1.4e-32 112.2 0.2 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.20 ORY10493.1 - 1e-25 91.2 0.0 3.5e-25 89.5 0.0 1.9 2 0 0 2 2 2 1 Thioesterase domain PS-DH PF14765.6 ORY10493.1 - 3.1e-12 46.4 0.0 6.1e-12 45.4 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 ORY10493.1 - 3.5e-05 24.2 0.0 0.00011 22.6 0.0 1.9 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 ORY10493.1 - 0.0001 21.7 0.0 0.00032 20.2 0.0 1.7 2 0 0 2 2 2 1 Thiolase, N-terminal domain Beta-lactamase2 PF13354.6 ORY10493.1 - 0.041 13.5 0.0 0.21 11.2 0.0 2.0 2 0 0 2 2 2 0 Beta-lactamase enzyme family Methyltransf_2 PF00891.18 ORY10494.1 - 2.2e-24 85.9 0.0 3.7e-24 85.2 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_12 PF08242.12 ORY10494.1 - 0.073 13.8 0.0 0.2 12.4 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Cu-oxidase_3 PF07732.15 ORY10495.1 - 3.1e-37 127.2 0.4 1.6e-36 124.9 0.1 2.3 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 ORY10495.1 - 4.3e-27 94.5 9.3 5.2e-23 81.3 1.0 3.7 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 ORY10495.1 - 6.5e-19 68.6 0.0 1.5e-18 67.4 0.0 1.6 1 1 0 1 1 1 1 Multicopper oxidase Fasciclin PF02469.22 ORY10496.1 - 3.7e-22 78.9 0.0 6.8e-18 65.1 0.0 2.3 2 0 0 2 2 2 2 Fasciclin domain Zn_clus PF00172.18 ORY10497.1 - 6.8e-07 29.3 12.8 1.8e-06 27.9 12.8 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 ORY10499.1 - 1.6e-36 126.0 49.8 9.6e-36 123.4 49.8 2.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Phage_holin_3_6 PF07332.11 ORY10499.1 - 0.18 11.8 0.1 0.18 11.8 0.1 5.3 4 2 1 5 5 5 0 Putative Actinobacterial Holin-X, holin superfamily III DUF5305 PF17231.2 ORY10499.1 - 0.23 10.8 0.2 1.4 8.2 0.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5305) Trp_oprn_chp PF09534.10 ORY10499.1 - 2.9 7.7 7.9 4.5 7.0 0.1 3.5 3 1 0 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) MASE5 PF17178.4 ORY10499.1 - 3.2 7.5 8.6 1.8 8.3 5.2 2.2 2 0 0 2 2 2 0 Membrane-associated sensor Sugar_tr PF00083.24 ORY10501.1 - 8.5e-58 196.3 14.6 1e-57 196.0 14.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY10501.1 - 1.9e-20 73.1 20.8 1.9e-20 73.1 20.8 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.6 ORY10501.1 - 5.1e-07 28.6 20.5 0.00013 20.6 1.9 3.3 3 1 1 4 4 4 2 MFS/sugar transport protein DUF2207 PF09972.9 ORY10501.1 - 0.0023 16.8 3.2 1.2 7.8 2.9 2.5 2 1 0 2 2 2 2 Predicted membrane protein (DUF2207) DUF3938 PF13074.6 ORY10501.1 - 0.013 15.8 5.5 0.076 13.3 1.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3938) CHAD PF05235.14 ORY10501.1 - 0.015 15.3 0.1 6.7 6.6 0.0 2.1 2 0 0 2 2 2 0 CHAD domain Folate_carrier PF01770.18 ORY10501.1 - 0.032 13.0 0.2 0.059 12.1 0.2 1.5 1 0 0 1 1 1 0 Reduced folate carrier MFS_1_like PF12832.7 ORY10501.1 - 0.17 10.7 13.6 1 8.2 4.3 2.8 2 1 1 3 3 3 0 MFS_1 like family AT_hook PF02178.19 ORY10503.1 - 0.0093 15.7 0.6 0.0093 15.7 0.6 3.1 3 0 0 3 3 3 1 AT hook motif NMT1 PF09084.11 ORY10504.1 - 7.6e-14 52.2 0.0 1.2e-13 51.5 0.0 1.3 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_3 PF16868.5 ORY10504.1 - 5.8e-07 29.2 0.0 8.8e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 NMT1-like family SBP_bac_3 PF00497.20 ORY10504.1 - 0.00021 20.8 0.0 0.00034 20.1 0.0 1.5 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Phosphonate-bd PF12974.7 ORY10504.1 - 0.0013 18.4 0.0 0.0016 18.1 0.0 1.3 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein Isochorismatase PF00857.20 ORY10504.1 - 0.024 14.8 0.0 0.037 14.2 0.0 1.2 1 0 0 1 1 1 0 Isochorismatase family hNIFK_binding PF12196.8 ORY10506.1 - 3 7.4 4.3 30 4.2 0.0 2.8 3 0 0 3 3 3 0 FHA Ki67 binding domain of hNIFK NmrA PF05368.13 ORY10508.1 - 2.4e-16 60.0 0.0 3.4e-16 59.5 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ORY10508.1 - 1.2e-15 57.8 0.0 2e-15 57.2 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 ORY10508.1 - 8.1e-05 22.2 0.0 0.0023 17.5 0.0 2.2 1 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 ORY10508.1 - 0.0025 18.1 0.0 0.0043 17.3 0.0 1.6 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain AP_endonuc_2 PF01261.24 ORY10508.1 - 0.0025 17.3 0.0 0.0038 16.7 0.0 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel RmlD_sub_bind PF04321.17 ORY10508.1 - 0.013 14.6 0.2 0.12 11.5 0.0 2.2 3 0 0 3 3 3 0 RmlD substrate binding domain 3Beta_HSD PF01073.19 ORY10508.1 - 0.061 12.3 0.0 0.14 11.1 0.0 1.6 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 ORY10508.1 - 0.071 13.5 0.0 0.18 12.3 0.0 1.6 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 ORY10508.1 - 0.22 10.9 0.0 0.38 10.1 0.0 1.5 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HhH-GPD PF00730.25 ORY10509.1 - 6.1e-05 23.4 0.0 6.3e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein MmgE_PrpD PF03972.14 ORY10510.1 - 4.6e-40 137.5 0.1 5.4e-40 137.3 0.1 1.0 1 0 0 1 1 1 1 MmgE/PrpD family Phage_TAC_9 PF10876.8 ORY10510.1 - 0.11 12.6 0.1 0.19 11.8 0.1 1.4 1 0 0 1 1 1 0 Phage tail assemb.y chaperone protein, TAC TAL_effector PF03377.13 ORY10510.1 - 0.12 12.7 0.1 0.45 10.9 0.0 1.9 2 0 0 2 2 2 0 TAL effector repeat Glyco_hydro_28 PF00295.17 ORY10512.1 - 1.2e-58 198.7 7.5 1.8e-58 198.2 7.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 AID PF18767.1 ORY10512.1 - 0.028 14.4 0.0 0.06 13.4 0.0 1.5 1 0 0 1 1 1 0 Activation induced deaminase NmrA PF05368.13 ORY10513.1 - 1.2e-26 93.7 0.1 2.7e-26 92.6 0.1 1.5 1 1 1 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.6 ORY10513.1 - 1.1e-07 31.9 0.0 1.6e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding LGT PF01790.18 ORY10515.1 - 0.034 13.4 1.9 0.042 13.1 1.9 1.1 1 0 0 1 1 1 0 Prolipoprotein diacylglyceryl transferase DUF4579 PF15158.6 ORY10515.1 - 0.054 13.2 0.8 0.068 12.9 0.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4579) SRP-alpha_N PF04086.13 ORY10516.1 - 0.75 9.7 10.0 0.94 9.3 10.0 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Zip PF02535.22 ORY10516.1 - 1.3 8.2 3.0 1.3 8.1 3.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter SPX PF03105.19 ORY10516.1 - 2.8 7.8 14.8 3.2 7.6 14.8 1.0 1 0 0 1 1 1 0 SPX domain Presenilin PF01080.17 ORY10516.1 - 7.1 5.3 9.1 8.3 5.1 9.1 1.1 1 0 0 1 1 1 0 Presenilin Sugar_tr PF00083.24 ORY10517.1 - 2.4e-09 36.6 4.6 2.6e-09 36.5 4.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter Caveolin PF01146.17 ORY10517.1 - 0.05 13.6 0.2 0.05 13.6 0.2 1.2 1 0 0 1 1 1 0 Caveolin HA2 PF04408.23 ORY10527.1 - 1.1e-21 77.1 0.0 1.1e-21 77.1 0.0 2.9 3 0 0 3 3 3 1 Helicase associated domain (HA2) Helicase_C PF00271.31 ORY10527.1 - 2.8e-13 50.2 0.2 2.7e-12 47.0 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 ORY10527.1 - 1.7e-08 34.4 1.4 7e-08 32.4 0.0 2.5 3 0 0 3 3 3 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.16 ORY10527.1 - 8.7e-08 32.4 0.0 2.2e-07 31.1 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_30 PF13604.6 ORY10527.1 - 0.00022 21.0 0.2 0.00088 19.0 0.1 2.0 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 ORY10527.1 - 0.00034 20.9 1.9 0.0012 19.1 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.6 ORY10527.1 - 0.0004 20.7 0.1 0.00098 19.5 0.1 1.6 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 ORY10527.1 - 0.00052 20.1 0.0 0.86 9.6 0.0 2.8 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_24 PF13479.6 ORY10527.1 - 0.011 15.5 0.0 0.028 14.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 ORY10527.1 - 0.058 12.4 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein PhoH PF02562.16 ORY10527.1 - 0.07 12.6 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein FtsK_SpoIIIE PF01580.18 ORY10527.1 - 0.096 12.0 0.4 0.37 10.1 0.0 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_23 PF13476.6 ORY10527.1 - 0.3 11.6 0.0 0.3 11.6 0.0 3.2 3 0 0 3 3 3 0 AAA domain PAC3 PF10178.9 ORY10528.1 - 4.2e-06 26.8 0.0 6.4e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Proteasome assembly chaperone 3 Fes1 PF08609.10 ORY10529.1 - 1.2e-14 54.9 0.8 3.8e-14 53.3 0.1 2.0 2 1 0 2 2 2 1 Nucleotide exchange factor Fes1 HEAT PF02985.22 ORY10529.1 - 7.6e-05 22.6 0.3 0.095 13.0 0.0 2.7 2 0 0 2 2 2 2 HEAT repeat HEAT_2 PF13646.6 ORY10529.1 - 0.00011 22.5 0.2 0.00028 21.2 0.1 1.7 2 0 0 2 2 2 1 HEAT repeats HEAT_EZ PF13513.6 ORY10529.1 - 0.065 13.8 0.2 3.9 8.1 0.0 2.8 3 0 0 3 3 3 0 HEAT-like repeat Actin PF00022.19 ORY10530.1 - 1.8e-143 478.0 0.0 7.2e-143 476.1 0.0 1.7 1 1 0 1 1 1 1 Actin MFS_1 PF07690.16 ORY10531.1 - 5e-26 91.5 34.3 5e-26 91.5 34.3 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY10531.1 - 2e-10 40.2 17.5 3.4e-09 36.1 17.5 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter Folate_carrier PF01770.18 ORY10531.1 - 4.5 5.9 12.2 0.077 11.7 2.0 2.3 3 0 0 3 3 3 0 Reduced folate carrier HMG_box PF00505.19 ORY10532.1 - 0.003 17.9 0.0 0.0075 16.7 0.0 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box LtrA PF06772.11 ORY10533.1 - 5.8e-24 85.0 19.8 7.7e-24 84.6 19.8 1.1 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) DUF4149 PF13664.6 ORY10533.1 - 7.7 6.9 11.9 7.8 6.9 1.6 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4149) IBR PF01485.21 ORY10534.1 - 6.1e-19 68.0 30.8 9.9e-13 48.1 1.1 4.5 3 2 1 4 4 4 2 IBR domain, a half RING-finger domain RWD PF05773.22 ORY10534.1 - 1.1e-16 61.2 0.0 2.3e-16 60.1 0.0 1.6 1 0 0 1 1 1 1 RWD domain zf-RING_2 PF13639.6 ORY10534.1 - 0.00023 21.4 4.6 0.00023 21.4 4.6 4.2 3 1 1 4 4 4 1 Ring finger domain zf-C3HC4 PF00097.25 ORY10534.1 - 0.0015 18.3 5.2 0.0015 18.3 5.2 4.6 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORY10534.1 - 0.012 15.7 5.0 0.012 15.7 5.0 3.5 3 0 0 3 3 3 0 RING-type zinc-finger zf-RING_5 PF14634.6 ORY10534.1 - 0.023 14.6 6.7 0.023 14.6 6.7 3.6 3 1 1 4 4 4 0 zinc-RING finger domain zf-RING_11 PF17123.5 ORY10534.1 - 3.6 7.4 18.8 0.036 13.8 4.4 3.8 3 1 1 4 4 4 0 RING-like zinc finger PAP2 PF01569.21 ORY10535.1 - 2.2e-12 46.9 5.4 2.2e-12 46.9 5.4 1.7 2 1 0 2 2 2 1 PAP2 superfamily DUF212 PF02681.14 ORY10535.1 - 0.0013 18.8 0.1 0.092 12.9 0.0 2.3 1 1 1 2 2 2 2 Divergent PAP2 family Sugar_tr PF00083.24 ORY10536.1 - 1.3e-84 284.7 23.2 1.5e-84 284.5 23.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY10536.1 - 6.3e-17 61.5 22.1 6.3e-17 61.5 22.1 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily MFA1_2 PF17317.2 ORY10536.1 - 0.25 11.2 0.6 0.59 10.0 0.6 1.7 1 0 0 1 1 1 0 Mating hormone A-factor 1&2 Sulfotransfer_4 PF17784.1 ORY10537.1 - 1.7e-33 116.3 0.0 2.5e-33 115.7 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase domain DUF2561 PF10812.8 ORY10537.1 - 0.078 13.0 1.6 0.18 11.8 1.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) Mito_carr PF00153.27 ORY10538.1 - 1.5e-30 104.9 0.8 2.8e-15 56.0 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Ras PF00071.22 ORY10539.1 - 2.2e-65 219.2 0.6 2.5e-65 219.0 0.6 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY10539.1 - 7.9e-36 122.9 0.1 1.3e-35 122.2 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY10539.1 - 2.8e-16 59.5 0.1 3.5e-16 59.2 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 ORY10539.1 - 1.8e-05 24.7 0.4 0.14 12.1 0.0 2.3 1 1 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 ORY10539.1 - 2.7e-05 24.2 0.0 9.9e-05 22.4 0.0 1.8 1 1 1 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 ORY10539.1 - 4.9e-05 22.9 0.4 0.00013 21.6 0.2 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 ORY10539.1 - 0.00026 20.4 0.1 0.00033 20.1 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA PF00004.29 ORY10539.1 - 0.00029 21.3 0.0 0.16 12.4 0.0 2.2 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) SRPRB PF09439.10 ORY10539.1 - 0.0006 19.3 0.0 0.00089 18.7 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 ORY10539.1 - 0.00093 18.8 0.0 0.0054 16.3 0.0 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_16 PF13191.6 ORY10539.1 - 0.01 16.3 0.0 0.013 15.8 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 ORY10539.1 - 0.03 14.3 0.0 0.13 12.3 0.0 2.1 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 ORY10539.1 - 0.033 14.4 0.0 0.071 13.4 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 ORY10539.1 - 0.05 13.3 0.0 0.15 11.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain TniB PF05621.11 ORY10539.1 - 0.083 12.3 0.0 0.25 10.7 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein AAA_7 PF12775.7 ORY10539.1 - 0.087 12.3 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Septin PF00735.18 ORY10539.1 - 0.087 12.1 0.0 0.19 11.0 0.0 1.5 1 0 0 1 1 1 0 Septin PduV-EutP PF10662.9 ORY10539.1 - 0.1 12.3 0.1 1 9.1 0.0 2.3 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.27 ORY10539.1 - 0.11 13.0 0.0 0.23 12.0 0.0 1.6 1 1 0 1 1 1 0 ABC transporter AAA_25 PF13481.6 ORY10539.1 - 0.12 11.9 0.1 1.6 8.3 0.0 2.2 2 1 0 2 2 2 0 AAA domain Epimerase PF01370.21 ORY10540.1 - 2.7e-20 72.9 0.0 4.2e-19 69.0 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ORY10540.1 - 1.3e-09 37.9 0.6 1.7e-08 34.3 0.1 2.5 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 ORY10540.1 - 1.6e-09 37.3 0.0 4.9e-06 25.9 0.0 2.6 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 ORY10540.1 - 1e-08 34.5 0.0 4.8e-08 32.3 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 ORY10540.1 - 4.1e-07 29.4 0.0 6.6e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 ORY10540.1 - 8.2e-07 28.5 0.0 4.9e-05 22.6 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.6 ORY10540.1 - 2.6e-06 27.5 0.0 4.3e-06 26.7 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding MMU163 PF17119.5 ORY10541.1 - 1.2e-89 299.7 7.0 7.2e-65 218.6 1.3 2.1 1 1 1 2 2 2 2 Mitochondrial protein up-regulated during meiosis EF-hand_4 PF12763.7 ORY10542.1 - 2.9e-34 117.1 0.0 3.3e-14 52.7 0.0 3.6 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.6 ORY10542.1 - 2.5e-08 34.3 0.0 0.00042 20.7 0.0 4.1 4 0 0 4 4 3 1 EF-hand domain pair EF-hand_1 PF00036.32 ORY10542.1 - 2.7e-08 32.8 0.0 0.26 10.9 0.0 5.1 5 0 0 5 5 5 2 EF hand EF-hand_6 PF13405.6 ORY10542.1 - 5.3e-06 25.9 0.2 1.5 9.0 0.1 5.2 5 0 0 5 5 5 1 EF-hand domain Macoilin PF09726.9 ORY10542.1 - 9.2e-06 24.5 7.6 9.2e-06 24.5 7.6 2.6 3 0 0 3 3 2 1 Macoilin family UBA PF00627.31 ORY10542.1 - 6.4e-05 22.8 0.1 0.00014 21.7 0.1 1.6 1 0 0 1 1 1 1 UBA/TS-N domain BicD PF09730.9 ORY10542.1 - 0.0013 17.3 20.7 0.0021 16.6 20.7 1.2 1 0 0 1 1 1 1 Microtubule-associated protein Bicaudal-D DUF3450 PF11932.8 ORY10542.1 - 0.0043 16.4 13.2 0.0043 16.4 13.2 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF3450) Tup_N PF08581.10 ORY10542.1 - 0.0048 17.2 5.1 0.0048 17.2 5.1 2.7 1 1 1 2 2 2 1 Tup N-terminal EF-hand_8 PF13833.6 ORY10542.1 - 0.01 15.6 0.0 10 6.0 0.0 3.6 4 0 0 4 4 3 0 EF-hand domain pair IL28A PF15177.6 ORY10542.1 - 0.018 14.9 1.9 0.044 13.6 1.9 1.6 1 0 0 1 1 1 0 Interleukin-28A GAS PF13851.6 ORY10542.1 - 0.05 13.0 28.7 0.073 12.4 14.6 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding TPR_MLP1_2 PF07926.12 ORY10542.1 - 0.068 13.2 28.5 0.53 10.4 17.5 2.6 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein EzrA PF06160.12 ORY10542.1 - 0.21 9.7 18.7 0.23 9.6 17.7 1.5 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA CENP-Q PF13094.6 ORY10542.1 - 0.7 10.1 24.8 0.42 10.8 20.6 2.4 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Nsp1_C PF05064.13 ORY10542.1 - 0.8 9.5 10.6 0.13 12.1 3.5 2.3 1 1 1 2 2 2 0 Nsp1-like C-terminal region Rab5-bind PF09311.11 ORY10542.1 - 0.99 8.7 22.8 2.5 7.4 22.8 1.6 1 1 0 1 1 1 0 Rabaptin-like protein CENP-F_leu_zip PF10473.9 ORY10542.1 - 1 9.3 28.9 0.43 10.6 7.6 2.8 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.11 ORY10542.1 - 1.4 7.7 29.5 1.1 8.1 14.9 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein APG6_N PF17675.1 ORY10542.1 - 1.8 9.1 29.7 1.2 9.7 12.1 3.0 1 1 1 3 3 3 0 Apg6 coiled-coil region Golgin_A5 PF09787.9 ORY10542.1 - 2 7.8 29.8 0.43 10.0 23.6 2.1 1 1 1 2 2 2 0 Golgin subfamily A member 5 Fez1 PF06818.15 ORY10542.1 - 2 8.8 27.3 12 6.3 27.5 2.1 1 1 0 1 1 1 0 Fez1 FPP PF05911.11 ORY10542.1 - 3 5.9 25.9 0.22 9.7 13.9 2.2 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil LPP PF04728.13 ORY10542.1 - 3.1 8.2 12.8 5.6 7.4 0.6 4.1 3 1 0 4 4 4 0 Lipoprotein leucine-zipper CALCOCO1 PF07888.11 ORY10542.1 - 3.9 6.2 26.7 8.5 5.1 26.7 1.4 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like IFT57 PF10498.9 ORY10542.1 - 4 6.3 28.5 2.5 7.0 7.5 2.3 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 DUF4200 PF13863.6 ORY10542.1 - 5.6 7.4 25.5 0.7 10.3 15.3 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Fib_alpha PF08702.10 ORY10542.1 - 6.1 7.0 22.2 0.23 11.6 10.8 2.4 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF4763 PF15960.5 ORY10542.1 - 6.2 6.0 23.0 1.3 8.3 11.3 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4763) YabA PF06156.13 ORY10542.1 - 6.2 7.5 20.4 3 8.6 3.0 3.3 1 1 2 3 3 3 0 Initiation control protein YabA ADIP PF11559.8 ORY10542.1 - 6.3 6.9 35.9 8.9 6.4 12.5 2.4 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF724 PF05266.14 ORY10542.1 - 7.1 6.4 23.3 0.086 12.7 7.8 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF724) HAUS-augmin3 PF14932.6 ORY10542.1 - 8.4 5.9 21.2 11 5.5 19.4 2.0 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 DUF3584 PF12128.8 ORY10542.1 - 10 3.5 29.6 15 2.9 29.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) WW PF00397.26 ORY10543.1 - 8.9e-10 38.5 4.5 2.1e-09 37.3 4.5 1.7 1 0 0 1 1 1 1 WW domain DAO PF01266.24 ORY10544.1 - 2e-67 228.2 1.0 2.4e-67 228.0 1.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 ORY10544.1 - 3.2e-06 26.3 0.3 0.011 14.6 0.1 2.1 2 0 0 2 2 2 2 Tryptophan halogenase Pyr_redox_2 PF07992.14 ORY10544.1 - 7.1e-06 25.5 0.1 0.0042 16.3 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORY10544.1 - 1.1e-05 25.6 0.2 2.4e-05 24.5 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 ORY10544.1 - 0.00016 21.7 0.2 0.7 9.9 0.0 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 ORY10544.1 - 0.00019 20.6 0.2 0.026 13.6 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Pyr_redox PF00070.27 ORY10544.1 - 0.00032 21.2 0.0 0.022 15.3 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 ORY10544.1 - 0.013 14.6 0.4 0.94 8.5 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Thi4 PF01946.17 ORY10544.1 - 0.034 13.4 0.1 0.063 12.5 0.1 1.4 1 0 0 1 1 1 0 Thi4 family MCRA PF06100.11 ORY10544.1 - 0.052 12.3 0.2 0.1 11.4 0.2 1.4 1 0 0 1 1 1 0 MCRA family Sacchrp_dh_NADP PF03435.18 ORY10544.1 - 0.16 12.2 0.1 0.36 11.1 0.1 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Vps51 PF08700.11 ORY10546.1 - 3.3e-13 49.5 0.0 1.9e-12 47.1 0.0 2.4 2 0 0 2 2 2 1 Vps51/Vps67 Dor1 PF04124.12 ORY10546.1 - 0.021 13.5 0.1 0.28 9.8 0.0 2.4 2 0 0 2 2 2 0 Dor1-like family DUF2433 PF10360.9 ORY10546.1 - 0.11 12.5 0.0 0.36 11.0 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2433) D123 PF07065.14 ORY10547.1 - 4.7e-117 390.5 0.1 5.6e-117 390.3 0.1 1.0 1 0 0 1 1 1 1 D123 cwf21 PF08312.12 ORY10548.1 - 2.8e-17 62.6 10.4 2.8e-17 62.6 10.4 2.0 3 0 0 3 3 3 1 cwf21 domain Trans_reg_C PF00486.28 ORY10548.1 - 2.7 8.1 8.5 1.1 9.4 0.1 2.9 3 1 1 4 4 4 0 Transcriptional regulatory protein, C terminal MFS_1 PF07690.16 ORY10549.1 - 1.3e-32 113.1 14.7 8.3e-32 110.5 11.6 1.4 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 ORY10549.1 - 5.9e-07 28.4 11.8 0.00095 17.8 6.4 3.1 3 0 0 3 3 3 3 MFS/sugar transport protein Sugar_tr PF00083.24 ORY10549.1 - 2.3e-06 26.8 13.2 0.01 14.7 10.4 3.0 2 1 1 3 3 3 2 Sugar (and other) transporter MFS_1_like PF12832.7 ORY10549.1 - 1e-05 24.6 14.9 0.0029 16.5 5.9 2.5 2 1 0 2 2 2 2 MFS_1 like family TRI12 PF06609.13 ORY10549.1 - 0.00013 20.5 1.6 0.00013 20.5 1.6 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 ORY10549.1 - 0.0083 14.5 13.8 0.42 8.8 0.2 3.7 2 1 0 4 4 4 2 Organic Anion Transporter Polypeptide (OATP) family MFS_3 PF05977.13 ORY10549.1 - 0.09 11.1 11.6 0.046 12.1 2.4 2.2 2 0 0 2 2 2 0 Transmembrane secretion effector Toxin_GhoT_OrtT PF10753.9 ORY10549.1 - 1.6 9.0 5.3 28 5.0 0.0 3.6 2 1 1 3 3 3 0 Toxin GhoT_OrtT Chorismate_bind PF00425.18 ORY10550.1 - 7e-66 222.4 0.1 4.5e-37 128.0 0.0 2.3 1 1 1 2 2 2 2 chorismate binding enzyme GATase PF00117.28 ORY10550.1 - 3.3e-29 102.0 0.0 9.7e-29 100.5 0.0 1.8 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.13 ORY10550.1 - 1.2e-17 64.5 0.0 2.4e-17 63.5 0.0 1.5 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.13 ORY10550.1 - 3.1e-08 33.6 0.1 8.2e-08 32.3 0.1 1.7 1 1 0 1 1 1 1 Peptidase C26 ASXH PF13919.6 ORY10551.1 - 1.5e-25 89.9 0.1 2.6e-25 89.1 0.1 1.4 1 0 0 1 1 1 1 Asx homology domain Longin PF13774.6 ORY10552.1 - 2.9e-25 88.1 0.2 5.6e-25 87.2 0.2 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 ORY10552.1 - 3.9e-15 55.4 0.0 6.2e-15 54.8 0.0 1.3 1 0 0 1 1 1 1 Synaptobrevin Abhydrolase_6 PF12697.7 ORY10553.1 - 1.4e-15 58.5 0.0 1.7e-15 58.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family PIF1 PF05970.14 ORY10553.1 - 0.099 11.8 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase Amidase PF01425.21 ORY10554.1 - 3.9e-79 266.7 0.0 1.8e-78 264.5 0.0 1.8 1 1 0 1 1 1 1 Amidase MMtag PF10159.9 ORY10555.1 - 1.4e-31 108.6 2.0 2.6e-31 107.7 2.0 1.4 1 0 0 1 1 1 1 Multiple myeloma tumor-associated Med6 PF04934.14 ORY10556.1 - 5.7e-22 78.0 0.0 8.8e-22 77.3 0.0 1.3 1 0 0 1 1 1 1 MED6 mediator sub complex component PsbQ PF05757.11 ORY10557.1 - 0.026 14.3 0.1 0.089 12.5 0.0 1.8 1 1 1 2 2 2 0 Oxygen evolving enhancer protein 3 (PsbQ) Pkinase PF00069.25 ORY10558.1 - 5.3e-55 186.6 0.0 7.3e-55 186.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY10558.1 - 5.6e-30 104.5 0.0 7.4e-30 104.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY10558.1 - 5.4e-10 39.1 0.0 1.2e-07 31.3 0.0 2.3 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 ORY10558.1 - 1.3e-06 28.5 0.3 0.00012 22.1 0.0 2.2 2 0 0 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 ORY10558.1 - 0.00088 18.7 0.1 0.0015 17.9 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family HAD_2 PF13419.6 ORY10561.1 - 5.8e-05 23.3 0.0 0.00018 21.7 0.0 1.7 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ORY10561.1 - 0.00022 21.2 0.0 0.0016 18.4 0.0 2.0 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 ORY10561.1 - 0.025 14.9 0.0 0.032 14.5 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase AsiA PF09010.10 ORY10561.1 - 0.16 12.1 0.0 0.32 11.2 0.0 1.5 1 0 0 1 1 1 0 Anti-Sigma Factor A PUF PF00806.19 ORY10564.1 - 7.5e-65 211.1 9.0 1.6e-09 36.9 0.1 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat Inhibitor_I9 PF05922.16 ORY10565.1 - 0.071 13.8 0.0 0.11 13.2 0.0 1.4 1 1 0 1 1 1 0 Peptidase inhibitor I9 SLBB PF10531.9 ORY10567.1 - 0.18 11.7 0.0 0.29 11.0 0.0 1.3 1 0 0 1 1 1 0 SLBB domain CAP_GLY PF01302.25 ORY10568.1 - 9.6e-26 89.6 0.0 1.4e-25 89.1 0.0 1.2 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.6 ORY10568.1 - 6.1e-20 71.5 0.0 8.8e-20 71.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like domain DUF1822 PF08852.11 ORY10568.1 - 0.0056 15.8 0.1 0.011 14.8 0.1 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1822) ubiquitin PF00240.23 ORY10568.1 - 0.0069 16.1 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Myb_DNA-binding PF00249.31 ORY10570.1 - 1.3e-14 54.1 2.7 3.9e-11 43.0 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORY10570.1 - 6.1e-07 29.6 2.9 0.0015 18.8 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain AGOG PF09171.10 ORY10570.1 - 0.096 12.0 0.1 0.14 11.5 0.1 1.1 1 0 0 1 1 1 0 N-glycosylase/DNA lyase Mif2_N PF15624.6 ORY10571.1 - 2.2e-42 145.0 3.1 2.2e-42 145.0 3.1 3.2 2 1 0 2 2 2 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal CENP-C_C PF11699.8 ORY10571.1 - 1.5e-25 89.2 0.4 2.7e-25 88.4 0.4 1.4 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_2 PF07883.11 ORY10571.1 - 6.1e-05 22.6 0.0 0.00011 21.8 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 ORY10571.1 - 0.0017 18.0 0.1 0.0034 17.0 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_1 PF00190.22 ORY10571.1 - 0.039 13.5 0.2 0.079 12.6 0.2 1.4 1 0 0 1 1 1 0 Cupin F-box PF00646.33 ORY10572.1 - 0.0093 15.8 0.2 0.025 14.4 0.2 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 ORY10572.1 - 0.018 14.9 0.2 0.043 13.7 0.2 1.6 1 0 0 1 1 1 0 F-box-like SAE2 PF08573.10 ORY10573.1 - 6.3e-27 94.9 0.0 6.3e-27 94.9 0.0 3.6 3 1 0 4 4 4 1 DNA repair protein endonuclease SAE2/CtIP C-terminus YabA PF06156.13 ORY10573.1 - 0.073 13.7 7.1 1.4 9.6 0.3 2.6 2 0 0 2 2 2 0 Initiation control protein YabA FAD_binding_2 PF00890.24 ORY10574.1 - 8.4e-42 143.7 0.0 2.3e-41 142.3 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 ORY10574.1 - 3.3e-09 36.8 2.6 1e-08 35.2 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ORY10574.1 - 6.1e-05 22.4 0.2 0.35 10.1 0.0 2.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ORY10574.1 - 7.6e-05 21.6 4.4 0.085 11.5 0.0 3.4 3 1 0 3 3 3 3 HI0933-like protein FAD_oxidored PF12831.7 ORY10574.1 - 8e-05 22.2 0.2 0.00033 20.1 0.1 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase GMC_oxred_N PF00732.19 ORY10574.1 - 0.0061 16.0 0.0 0.018 14.5 0.0 1.7 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_3 PF01494.19 ORY10574.1 - 0.021 14.1 0.1 0.15 11.3 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_3 PF13738.6 ORY10574.1 - 0.054 12.8 0.0 1 8.6 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 ORY10574.1 - 0.13 11.3 3.4 0.51 9.4 0.1 2.7 3 0 0 3 3 3 0 Glucose inhibited division protein A adh_short PF00106.25 ORY10575.1 - 2.7e-39 134.6 0.3 3.9e-39 134.1 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY10575.1 - 2.4e-27 96.0 0.2 3.6e-27 95.4 0.2 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY10575.1 - 6.2e-07 29.5 1.6 3e-06 27.3 1.6 1.9 1 1 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 ORY10575.1 - 0.0008 18.5 0.1 0.0012 17.9 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 ORY10575.1 - 0.003 17.0 0.0 0.0044 16.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Peptidase_M28 PF04389.17 ORY10576.1 - 4.8e-41 140.6 0.3 7e-41 140.1 0.3 1.2 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 ORY10576.1 - 2.3e-15 56.4 0.8 6.7e-15 54.9 0.2 2.1 2 0 0 2 2 2 1 PA domain Peptidase_M20 PF01546.28 ORY10576.1 - 2.1e-05 24.3 0.1 5.7e-05 22.9 0.2 1.7 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 ORY10576.1 - 0.057 12.4 0.0 0.15 11.1 0.0 1.6 1 0 0 1 1 1 0 M42 glutamyl aminopeptidase FAD_binding_3 PF01494.19 ORY10578.1 - 9.2e-79 265.2 0.0 1.2e-78 264.8 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 ORY10578.1 - 0.0092 15.2 0.2 0.016 14.4 0.2 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORY10578.1 - 0.014 15.6 1.2 0.033 14.4 1.2 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAA_hydrolase PF01557.18 ORY10579.1 - 2.9e-66 223.3 0.0 5.6e-66 222.3 0.0 1.4 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Ssl1 PF04056.14 ORY10579.1 - 2.6e-20 73.0 0.2 6e-16 58.8 0.0 2.4 1 1 1 2 2 2 2 Ssl1-like C1_4 PF07975.12 ORY10579.1 - 3.6e-14 52.7 12.6 3.6e-14 52.7 12.6 3.7 2 2 0 2 2 2 1 TFIIH C1-like domain VWA_2 PF13519.6 ORY10579.1 - 0.00058 20.5 0.0 0.0012 19.4 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF2437 PF10370.9 ORY10579.1 - 0.083 13.8 0.0 0.17 12.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2437) zf-HIT PF04438.16 ORY10579.1 - 0.99 9.3 24.1 0.026 14.4 5.0 3.5 4 0 0 4 4 4 0 HIT zinc finger Tfb4 PF03850.14 ORY10579.1 - 1 8.8 3.9 1.9 7.9 3.9 1.4 1 0 0 1 1 1 0 Transcription factor Tfb4 Chs7 PF12271.8 ORY10580.1 - 2e-110 368.7 8.5 2.3e-110 368.5 8.5 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone Sugar_tr PF00083.24 ORY10581.1 - 6.3e-104 348.3 15.4 7.8e-104 348.0 15.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY10581.1 - 1e-25 90.4 33.9 1.3e-22 80.3 29.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 ORY10581.1 - 2.2e-05 23.2 18.2 0.00015 20.5 3.2 2.8 3 0 0 3 3 3 2 MFS/sugar transport protein MFS_1_like PF12832.7 ORY10581.1 - 0.0028 16.6 5.0 0.25 10.2 1.6 2.3 2 0 0 2 2 2 2 MFS_1 like family PMT PF02366.18 ORY10582.1 - 2.5e-88 295.8 14.5 2.5e-88 295.8 14.5 2.0 2 1 1 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 ORY10582.1 - 3e-66 222.8 15.4 3e-66 222.8 15.4 2.4 2 1 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 ORY10582.1 - 2.6e-34 118.7 2.1 4e-34 118.1 2.1 1.2 1 0 0 1 1 1 1 MIR domain JCAD PF15351.6 ORY10583.1 - 0.018 12.9 1.2 0.024 12.4 1.2 1.1 1 0 0 1 1 1 0 Junctional protein associated with coronary artery disease Metallophos PF00149.28 ORY10584.1 - 1.4e-32 113.9 0.0 2.1e-32 113.3 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.12 ORY10584.1 - 1.6e-18 66.7 0.1 2.9e-18 66.0 0.1 1.4 1 0 0 1 1 1 1 PPP5 TPR repeat region Spt4 PF06093.13 ORY10585.1 - 3.6e-31 107.1 0.4 4.4e-31 106.8 0.4 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger Coronavirus_5 PF05528.11 ORY10585.1 - 0.067 13.2 0.0 0.095 12.7 0.0 1.3 1 0 0 1 1 1 0 Coronavirus gene 5 protein Mid1 PF12929.7 ORY10586.1 - 2.5e-147 491.5 0.1 3e-147 491.2 0.1 1.1 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.22 ORY10586.1 - 8.5e-06 26.4 4.9 0.00018 22.1 1.3 2.6 2 0 0 2 2 2 2 Fz domain AMP-binding PF00501.28 ORY10587.1 - 1.5e-88 297.2 0.0 2.2e-88 296.7 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Luteo_P1-P2 PF08467.10 ORY10587.1 - 0.046 13.0 0.0 0.072 12.3 0.0 1.2 1 0 0 1 1 1 0 Luteovirus RNA polymerase P1-P2/replicase Cys_Met_Meta_PP PF01053.20 ORY10588.1 - 3.9e-152 506.2 0.0 4.5e-152 506.0 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 ORY10588.1 - 2e-10 40.5 0.1 3.1e-10 39.9 0.1 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 ORY10588.1 - 2.4e-10 40.1 0.0 6.4e-10 38.7 0.0 1.6 2 0 0 2 2 2 1 Aminotransferase class I and II Aminotran_5 PF00266.19 ORY10588.1 - 1.1e-07 31.1 0.1 2e-07 30.3 0.1 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 ORY10588.1 - 4.9e-05 22.7 0.0 8e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.11 ORY10588.1 - 0.00083 18.0 0.1 0.0011 17.6 0.1 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase UCR_Fe-S_N PF10399.9 ORY10589.1 - 0.097 12.0 1.4 0.2 11.0 1.4 1.5 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal FAM220 PF15487.6 ORY10589.1 - 1.5 8.4 4.9 3.5 7.2 4.9 1.6 1 1 0 1 1 1 0 FAM220 family Velvet PF11754.8 ORY10590.1 - 3.8e-50 171.2 0.0 1.1e-31 110.7 0.0 4.6 2 2 1 3 3 3 2 Velvet factor Lzipper-MIP1 PF14389.6 ORY10612.1 - 0.065 13.5 0.4 0.87 9.9 1.2 2.2 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Lipase_3 PF01764.25 ORY10613.1 - 5.1e-15 55.6 0.0 1.3e-14 54.3 0.0 1.6 2 0 0 2 2 2 1 Lipase (class 3) Abhydrolase_6 PF12697.7 ORY10613.1 - 6.9e-05 23.5 1.0 0.00013 22.7 1.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.8 ORY10613.1 - 0.0024 17.4 0.0 0.011 15.3 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF2974) DUF676 PF05057.14 ORY10613.1 - 0.041 13.4 0.0 0.067 12.7 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Trigger_C PF05698.14 ORY10613.1 - 0.048 13.7 0.0 0.07 13.1 0.0 1.2 1 0 0 1 1 1 0 Bacterial trigger factor protein (TF) C-terminus PGAP1 PF07819.13 ORY10613.1 - 0.067 12.9 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein SAP PF02037.27 ORY10615.1 - 3e-09 36.4 0.0 5e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 SAP domain FAM176 PF14851.6 ORY10615.1 - 0.002 17.8 4.8 0.0031 17.2 4.8 1.3 1 0 0 1 1 1 1 FAM176 family Tim54 PF11711.8 ORY10615.1 - 0.0076 15.1 5.0 0.0089 14.9 5.0 1.1 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 DUF4569 PF15133.6 ORY10615.1 - 0.09 12.5 5.2 0.13 12.0 5.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) CPSF100_C PF13299.6 ORY10615.1 - 0.18 12.0 3.6 0.3 11.3 3.6 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal FAM76 PF16046.5 ORY10615.1 - 0.48 9.7 8.0 0.61 9.4 8.0 1.1 1 0 0 1 1 1 0 FAM76 protein NPR3 PF03666.13 ORY10615.1 - 0.98 8.1 6.7 1.1 8.0 6.7 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Presenilin PF01080.17 ORY10615.1 - 3.1 6.5 6.7 3.5 6.3 6.7 1.1 1 0 0 1 1 1 0 Presenilin adh_short PF00106.25 ORY10616.1 - 2.8e-12 46.5 0.0 3.9e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORY10616.1 - 4.3e-08 33.3 0.0 6.8e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 ORY10616.1 - 6e-07 29.3 0.0 9.2e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase His_Phos_2 PF00328.22 ORY10617.1 - 0.0011 18.4 0.0 0.55 9.5 0.0 2.4 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) ECH_1 PF00378.20 ORY10618.1 - 7.8e-49 166.2 0.0 1.2e-48 165.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ORY10618.1 - 6.4e-25 88.3 0.0 1.2e-21 77.6 0.0 2.1 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 ORY10618.1 - 0.00053 20.0 0.0 0.27 11.2 0.0 2.2 2 0 0 2 2 2 2 Peptidase family S49 DUF3425 PF11905.8 ORY10619.1 - 1.6e-20 73.3 2.4 2.5e-20 72.7 2.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 ORY10619.1 - 0.0022 18.0 7.3 0.0094 16.0 7.3 2.0 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 ORY10619.1 - 0.0052 16.8 7.7 1 9.5 6.8 2.4 2 0 0 2 2 2 2 Basic region leucine zipper NMO PF03060.15 ORY10620.1 - 1.4e-52 179.1 0.5 2.3e-52 178.4 0.5 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 ORY10620.1 - 9e-10 38.1 0.4 0.0003 19.9 0.0 2.8 3 1 0 3 3 3 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 ORY10620.1 - 0.00041 19.5 2.4 0.00082 18.5 2.1 1.6 1 1 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 ORY10620.1 - 0.0021 17.3 0.2 0.0037 16.5 0.2 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.21 ORY10620.1 - 0.094 12.2 0.5 0.67 9.4 0.0 2.1 2 0 0 2 2 2 0 Histidine biosynthesis protein Nnf1 PF03980.14 ORY10620.1 - 0.11 12.9 0.0 0.22 11.9 0.0 1.5 1 0 0 1 1 1 0 Nnf1 AMP-binding PF00501.28 ORY10621.1 - 1.9e-87 293.6 0.0 2.3e-87 293.3 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORY10621.1 - 3.3e-10 40.8 0.0 4.5e-09 37.2 0.0 2.3 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DASH_Spc19 PF08287.11 ORY10622.1 - 4.1e-53 179.5 3.9 4.1e-53 179.5 3.9 1.4 2 0 0 2 2 2 1 Spc19 ATP-synt_J PF04911.12 ORY10623.1 - 2.2e-23 81.5 0.6 2.4e-23 81.4 0.6 1.0 1 0 0 1 1 1 1 ATP synthase j chain Pkinase PF00069.25 ORY10624.1 - 2.3e-26 92.8 0.0 2.8e-26 92.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY10624.1 - 6.1e-14 51.9 0.0 8.4e-14 51.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORY10624.1 - 3.9e-09 35.8 0.0 6e-09 35.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 ORY10624.1 - 0.00017 21.6 0.0 0.0014 18.6 0.0 2.1 1 1 0 2 2 2 1 Phosphotransferase enzyme family Rsm22 PF09243.10 ORY10625.1 - 2.2e-30 105.9 0.0 4.8e-21 75.2 0.0 3.0 3 0 0 3 3 3 2 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_23 PF13489.6 ORY10625.1 - 0.0076 16.1 0.0 0.017 15.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain FAD_binding_4 PF01565.23 ORY10626.1 - 2.1e-37 128.0 2.9 3.7e-37 127.2 2.9 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 ORY10626.1 - 7e-07 29.3 0.6 1.5e-06 28.2 0.6 1.5 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.10 ORY10626.1 - 0.21 10.9 0.0 0.34 10.3 0.0 1.3 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding COesterase PF00135.28 ORY10627.1 - 5.2e-95 319.2 0.0 6.7e-95 318.9 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 ORY10627.1 - 0.0016 18.3 0.1 0.15 11.9 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold EpmC PF04315.12 ORY10628.1 - 0.035 13.8 0.1 0.066 12.9 0.1 1.4 1 0 0 1 1 1 0 Elongation factor P hydroxylase Afi1 PF07792.12 ORY10630.1 - 1.8e-44 151.4 0.4 1.8e-44 151.4 0.4 1.8 2 0 0 2 2 2 1 Docking domain of Afi1 for Arf3 in vesicle trafficking SPA PF08616.10 ORY10630.1 - 8.9e-37 125.5 0.0 1.5e-36 124.8 0.0 1.4 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.9 ORY10630.1 - 2.1e-08 33.3 0.0 0.062 12.0 0.0 4.1 3 1 1 4 4 4 3 Transport protein Avl9 DUF2347 PF09804.9 ORY10630.1 - 0.0076 15.9 0.1 0.043 13.4 0.0 2.2 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2347) BUD22 PF09073.10 ORY10630.1 - 0.029 13.7 4.1 0.057 12.8 4.1 1.4 1 0 0 1 1 1 0 BUD22 Cwf_Cwc_15 PF04889.12 ORY10630.1 - 0.74 9.5 13.8 0.023 14.4 7.7 1.5 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein DUF1168 PF06658.12 ORY10630.1 - 3.2 7.6 14.3 0.05 13.4 6.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1168) EF-hand_6 PF13405.6 ORY10631.1 - 2.9e-11 42.3 0.0 4.1e-05 23.2 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 ORY10631.1 - 2.2e-08 33.1 0.4 0.0031 16.9 0.2 2.4 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 ORY10631.1 - 7.3e-08 32.8 1.3 1.1e-05 25.8 0.1 2.0 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 ORY10631.1 - 6.6e-06 26.4 0.0 0.16 12.3 0.0 2.5 2 1 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 ORY10631.1 - 9.9e-05 22.1 0.1 0.13 12.1 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 ORY10631.1 - 0.00065 19.1 1.8 0.13 11.8 0.5 2.3 2 0 0 2 2 2 2 EF hand QWRF PF04484.12 ORY10631.1 - 3.4 7.3 10.6 4.9 6.8 10.6 1.3 1 0 0 1 1 1 0 QWRF family DUF3176 PF11374.8 ORY10632.1 - 6.7e-31 106.7 0.2 2.2e-30 105.0 0.1 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF3176) HET PF06985.11 ORY10633.1 - 1.8e-23 83.5 0.0 5.3e-23 82.0 0.0 1.8 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HET PF06985.11 ORY10634.1 - 3.5e-26 92.3 3.8 3.5e-24 85.8 3.8 2.3 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF815 PF05673.13 ORY10634.1 - 0.16 11.1 0.0 0.24 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Methyltrn_RNA_3 PF02598.17 ORY10636.1 - 1.7e-91 306.7 0.0 2.6e-91 306.1 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methyltransferase Adaptin_N PF01602.20 ORY10638.1 - 7.3e-114 381.2 0.0 9.7e-114 380.8 0.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 ORY10638.1 - 9.8e-59 197.8 3.6 2.1e-58 196.8 3.6 1.6 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 ORY10638.1 - 1.5e-33 115.3 0.2 4.9e-33 113.7 0.2 2.0 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 ORY10638.1 - 2.2e-17 63.2 1.0 1.4e-09 38.2 0.0 5.9 2 1 4 6 6 6 4 HEAT repeats Cnd1 PF12717.7 ORY10638.1 - 4e-06 27.0 9.7 0.1 12.6 0.2 4.5 4 1 0 4 4 4 3 non-SMC mitotic condensation complex subunit 1 HEAT_PBS PF03130.16 ORY10638.1 - 0.011 16.3 0.4 10 7.1 0.0 4.5 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat Coatomer_b_Cpla PF14806.6 ORY10638.1 - 0.012 15.6 0.0 0.047 13.7 0.0 2.0 2 0 0 2 2 2 0 Coatomer beta subunit appendage platform HEAT PF02985.22 ORY10638.1 - 0.11 12.9 8.8 3.3 8.2 0.3 5.8 6 0 0 6 6 6 0 HEAT repeat SAM_LFY PF01698.16 ORY10638.1 - 0.18 11.8 1.5 1.7 8.6 0.0 3.0 3 0 0 3 3 3 0 Floricaula / Leafy protein SAM domain HEAT_EZ PF13513.6 ORY10638.1 - 1 9.9 3.5 2.3 8.8 0.2 3.2 3 0 0 3 3 3 0 HEAT-like repeat LIAS_N PF16881.5 ORY10639.1 - 9.1e-27 93.6 0.1 1.8e-26 92.6 0.1 1.5 1 0 0 1 1 1 1 N-terminal domain of lipoyl synthase of Radical_SAM family Radical_SAM PF04055.21 ORY10639.1 - 1e-11 45.5 0.0 1.7e-11 44.8 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily WD40 PF00400.32 ORY10640.1 - 0.0016 19.2 0.0 0.0056 17.5 0.0 1.9 2 0 0 2 2 2 1 WD domain, G-beta repeat MSA-2c PF12238.8 ORY10641.1 - 0.1 12.6 4.0 0.28 11.2 4.0 1.7 1 0 0 1 1 1 0 Merozoite surface antigen 2c EI24 PF07264.11 ORY10642.1 - 8.1e-14 52.3 3.1 1.2e-13 51.7 3.1 1.3 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) PX PF00787.24 ORY10643.1 - 8.7e-27 93.4 0.0 1e-26 93.1 0.0 1.1 1 0 0 1 1 1 1 PX domain SSF PF00474.17 ORY10644.1 - 1.5e-06 27.4 32.6 5.9e-05 22.1 32.6 2.4 1 1 0 1 1 1 1 Sodium:solute symporter family Phosducin PF02114.16 ORY10645.1 - 1.6e-10 40.3 0.1 2.5e-10 39.8 0.1 1.2 1 0 0 1 1 1 1 Phosducin bZIP_1 PF00170.21 ORY10646.1 - 5.9e-07 29.5 12.7 5.9e-07 29.5 12.7 1.7 2 0 0 2 2 2 1 bZIP transcription factor PAP1 PF08601.10 ORY10646.1 - 1.4e-06 28.3 0.0 1.4e-06 28.3 0.0 2.2 1 1 1 2 2 2 1 Transcription factor PAP1 SHE3 PF17078.5 ORY10646.1 - 0.0045 16.7 5.2 0.0067 16.2 5.2 1.2 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 DUF812 PF05667.11 ORY10646.1 - 0.0073 15.2 0.7 0.0073 15.2 0.7 1.3 2 0 0 2 2 2 1 Protein of unknown function (DUF812) ADIP PF11559.8 ORY10646.1 - 0.0074 16.4 11.4 0.012 15.7 11.4 1.3 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding HSD3 PF15244.6 ORY10646.1 - 0.008 15.7 0.7 0.008 15.7 0.7 1.7 1 1 0 1 1 1 1 Spermatogenesis-associated protein 7, or HSD3 bZIP_Maf PF03131.17 ORY10646.1 - 0.056 14.0 13.3 0.11 13.0 13.3 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor bZIP_2 PF07716.15 ORY10646.1 - 0.058 13.5 13.2 0.04 14.0 10.6 2.0 1 1 1 2 2 2 0 Basic region leucine zipper DUF1929 PF09118.11 ORY10646.1 - 0.14 12.4 0.0 0.26 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1929) V_ATPase_I PF01496.19 ORY10646.1 - 0.16 9.9 3.1 0.19 9.6 3.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family GvpL_GvpF PF06386.11 ORY10646.1 - 0.32 10.9 8.1 0.54 10.1 8.1 1.3 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF Jnk-SapK_ap_N PF09744.9 ORY10646.1 - 0.44 10.8 7.3 0.75 10.0 7.3 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 UPF0242 PF06785.11 ORY10646.1 - 1.4 9.0 5.7 2 8.5 5.7 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus RskA PF10099.9 ORY10647.1 - 0.0044 17.3 1.7 0.0076 16.6 1.7 1.3 1 0 0 1 1 1 1 Anti-sigma-K factor rskA SKG6 PF08693.10 ORY10647.1 - 0.0062 15.9 3.3 0.0062 15.9 3.3 1.6 2 0 0 2 2 2 1 Transmembrane alpha-helix domain DUF4971 PF16341.5 ORY10650.1 - 0.049 13.4 0.0 0.08 12.8 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4971) Zn_clus PF00172.18 ORY10651.1 - 1.6e-15 56.9 26.8 1.4e-07 31.5 11.4 2.3 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain F_bP_aldolase PF01116.20 ORY10652.1 - 6.3e-85 285.0 0.0 7e-85 284.9 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Methyltransf_24 PF13578.6 ORY10652.1 - 0.12 13.4 0.0 0.22 12.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain NAD_binding_11 PF14833.6 ORY10653.1 - 3.8e-39 133.7 0.0 4.7e-25 88.2 0.0 2.3 2 0 0 2 2 2 2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.15 ORY10653.1 - 1.8e-32 112.7 0.3 2.9e-32 112.0 0.3 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 ORY10653.1 - 0.0013 19.3 0.0 0.0035 17.9 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 ORY10653.1 - 0.0032 17.4 0.1 0.0051 16.7 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 ORY10653.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Peptidase_S8 PF00082.22 ORY10655.1 - 9e-15 54.7 0.0 1.5e-14 54.0 0.0 1.2 1 0 0 1 1 1 1 Subtilase family Phasin_2 PF09361.10 ORY10656.1 - 0.012 15.8 0.0 0.12 12.7 0.0 2.3 1 1 1 2 2 2 0 Phasin protein Hemagglutinin PF00509.18 ORY10656.1 - 0.075 11.4 0.8 0.14 10.5 0.8 1.4 1 0 0 1 1 1 0 Haemagglutinin BAR_3_WASP_bdg PF10456.9 ORY10656.1 - 0.099 12.1 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 WASP-binding domain of Sorting nexin protein TAT_signal PF10518.9 ORY10656.1 - 0.11 12.4 0.3 0.47 10.4 0.3 2.1 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence SF-assemblin PF06705.11 ORY10656.1 - 0.17 11.2 0.9 0.28 10.5 0.9 1.3 1 0 0 1 1 1 0 SF-assemblin/beta giardin CelTOS PF18659.1 ORY10656.1 - 0.82 10.1 4.6 4.2 7.8 4.2 2.1 1 1 1 2 2 2 0 Cell-traversal protein for ookinetes and sporozoites SseC PF04888.12 ORY10656.1 - 1.7 8.1 4.3 8.2 5.9 2.5 2.1 1 1 1 2 2 2 0 Secretion system effector C (SseC) like family Baculo_PEP_C PF04513.12 ORY10656.1 - 3.2 7.8 7.5 0.31 11.1 2.2 2.0 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus AA_permease PF00324.21 ORY10657.1 - 1.3e-151 505.5 40.5 1.5e-151 505.3 40.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ORY10657.1 - 5.6e-35 121.0 44.7 9.8e-35 120.2 44.7 1.4 1 0 0 1 1 1 1 Amino acid permease DUF4781 PF16013.5 ORY10657.1 - 0.074 11.8 1.3 0.13 11.1 1.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4781) Glyco_transf_8 PF01501.20 ORY10660.1 - 8.1e-05 22.3 0.0 0.00017 21.2 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 8 Abhydrolase_1 PF00561.20 ORY10661.1 - 1.5e-22 80.5 0.2 2.2e-22 80.0 0.2 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORY10661.1 - 6.3e-17 62.9 0.1 8.5e-17 62.5 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORY10661.1 - 3.4e-15 56.0 1.8 4e-15 55.8 0.8 1.5 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Chlorophyllase PF07224.11 ORY10661.1 - 0.00036 19.7 0.1 0.0006 18.9 0.1 1.3 1 1 0 1 1 1 1 Chlorophyllase Thioesterase PF00975.20 ORY10661.1 - 0.00074 19.7 0.0 0.0012 19.0 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain DUF915 PF06028.11 ORY10661.1 - 0.0016 17.9 0.2 0.054 12.8 0.1 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) DLH PF01738.18 ORY10661.1 - 0.002 17.7 0.1 0.03 13.9 0.0 2.5 2 1 0 2 2 2 1 Dienelactone hydrolase family DUF1057 PF06342.12 ORY10661.1 - 0.0025 16.9 0.0 0.0039 16.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Abhydrolase_3 PF07859.13 ORY10661.1 - 0.011 15.6 0.1 0.033 14.1 0.0 1.7 1 1 0 1 1 1 0 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 ORY10661.1 - 0.027 13.4 0.1 0.039 12.9 0.1 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme PAN_4 PF14295.6 ORY10663.1 - 0.00061 19.6 1.8 0.0014 18.5 1.8 1.6 1 0 0 1 1 1 1 PAN domain PAN_3 PF08277.12 ORY10663.1 - 0.01 15.6 1.7 0.023 14.5 1.7 1.6 1 0 0 1 1 1 0 PAN-like domain PRCC PF10253.9 ORY10663.1 - 0.49 11.2 5.0 0.62 10.8 5.0 1.2 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Methyltransf_25 PF13649.6 ORY10664.1 - 1.6e-06 28.7 0.0 3.1e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY10664.1 - 0.00039 21.1 0.0 0.00082 20.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY10664.1 - 0.0016 19.0 0.0 0.003 18.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY10664.1 - 0.15 11.8 0.0 0.19 11.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain MFS_1 PF07690.16 ORY10665.1 - 2.3e-28 99.2 46.7 1.1e-18 67.3 23.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MARVEL PF01284.23 ORY10666.1 - 4.2e-08 33.3 3.4 5e-08 33.1 3.4 1.1 1 0 0 1 1 1 1 Membrane-associating domain Herpes_LMP1 PF05297.11 ORY10666.1 - 0.11 11.7 3.0 0.13 11.4 3.0 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) DUF1932 PF09130.11 ORY10667.1 - 1.3e-21 76.3 0.0 5.7e-21 74.3 0.0 2.1 2 1 0 2 2 2 1 Domain of unknown function (DUF1932) NAD_binding_2 PF03446.15 ORY10667.1 - 2.1e-08 34.5 0.0 3.7e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 ORY10667.1 - 2.1e-06 28.2 0.0 4.6e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 ORY10667.1 - 0.0018 17.7 0.0 0.003 17.0 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 ORY10667.1 - 0.031 14.2 0.0 0.05 13.5 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Rossmann-like PF10727.9 ORY10667.1 - 0.047 13.6 1.5 0.06 13.2 0.4 1.8 2 0 0 2 2 2 0 Rossmann-like domain F-box-like PF12937.7 ORY10669.1 - 5.6e-06 26.2 0.0 1.8e-05 24.5 0.0 2.0 1 1 0 1 1 1 1 F-box-like Fungal_trans PF04082.18 ORY10670.1 - 2.1e-11 43.4 0.1 3.3e-11 42.7 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY10670.1 - 4.8e-09 36.2 10.4 1.1e-08 35.0 10.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TFIIS_M PF07500.14 ORY10671.1 - 0.0051 17.3 0.0 0.0083 16.6 0.0 1.3 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain RhgB_N PF09284.10 ORY10674.1 - 4.5e-113 376.9 4.2 6.8e-113 376.3 4.2 1.3 1 0 0 1 1 1 1 Rhamnogalacturonan lyase B, N-terminal CBM-like PF14683.6 ORY10674.1 - 6.8e-41 139.9 0.0 2.9e-40 137.9 0.0 2.0 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.6 ORY10674.1 - 1.9e-23 82.0 4.9 6.7e-23 80.3 4.9 2.0 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.6 ORY10674.1 - 0.00034 20.8 1.6 0.00034 20.8 1.6 2.7 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 ORY10674.1 - 0.054 13.5 0.1 0.18 11.8 0.1 1.8 1 0 0 1 1 1 0 CarboxypepD_reg-like domain Agarase_CBM PF17992.1 ORY10674.1 - 0.13 11.9 0.1 0.27 10.8 0.1 1.5 1 0 0 1 1 1 0 Agarase CBM like domain Aldolase_II PF00596.21 ORY10675.1 - 3.2e-35 121.8 0.1 4.9e-35 121.1 0.1 1.3 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain CDH-cyt PF16010.5 ORY10677.1 - 8.3e-50 169.0 9.7 9.3e-50 168.8 9.7 1.0 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase Big_3_5 PF16640.5 ORY10677.1 - 0.96 9.7 10.4 2.7 8.3 5.6 2.9 2 1 1 3 3 3 0 Bacterial Ig-like domain (group 3) DUF1996 PF09362.10 ORY10678.1 - 1.5e-70 237.9 2.6 2e-70 237.4 2.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Cation_ATPase_C PF00689.21 ORY10679.1 - 1.7e-33 115.9 0.2 1.7e-33 115.9 0.2 1.8 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 ORY10679.1 - 9.7e-28 96.9 0.2 9.7e-28 96.9 0.2 1.7 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 ORY10679.1 - 2.4e-21 77.0 0.0 1.8e-11 44.8 0.0 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 ORY10679.1 - 3.8e-12 46.1 0.0 7.9e-12 45.1 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 ORY10679.1 - 1.8e-11 43.6 0.0 3.6e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 ORY10679.1 - 0.0042 16.9 0.0 0.0086 15.8 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase ATP-synt_I PF03899.15 ORY10679.1 - 0.45 10.9 3.3 0.27 11.6 0.2 2.2 2 0 0 2 2 2 0 ATP synthase I chain DJ-1_PfpI PF01965.24 ORY10680.1 - 2.8e-18 66.2 0.0 4.3e-18 65.6 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 ORY10680.1 - 2.6e-06 27.3 0.0 4.8e-06 26.4 0.0 1.4 2 0 0 2 2 2 1 ThiJ/PfpI family-like GATase_5 PF13507.6 ORY10680.1 - 0.035 13.2 0.0 0.052 12.6 0.0 1.2 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain SNO PF01174.19 ORY10680.1 - 0.043 13.7 0.0 0.075 12.9 0.0 1.3 1 0 0 1 1 1 0 SNO glutamine amidotransferase family PAP2_3 PF14378.6 ORY10682.1 - 9.2e-38 129.8 15.2 1.3e-37 129.3 15.2 1.2 1 0 0 1 1 1 1 PAP2 superfamily PAP2 PF01569.21 ORY10682.1 - 0.00097 18.9 5.6 0.00097 18.9 5.6 2.3 2 0 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.6 ORY10682.1 - 0.012 16.1 0.6 0.012 16.1 0.6 2.5 2 0 0 2 2 2 0 PAP2 superfamily C-terminal CATSPERD PF15020.6 ORY10682.1 - 0.26 9.5 1.0 0.38 9.0 1.0 1.2 1 0 0 1 1 1 0 Cation channel sperm-associated protein subunit delta PIG-S PF10510.9 ORY10683.1 - 1.9e-179 597.8 3.7 2.2e-179 597.6 3.7 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein DUF4398 PF14346.6 ORY10683.1 - 0.59 10.8 3.7 5.6 7.7 0.1 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4398) tRNA-synt_1 PF00133.22 ORY10684.1 - 1.4e-154 515.7 0.0 2.3e-154 515.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 ORY10684.1 - 3.4e-23 82.0 3.3 1e-16 60.7 0.0 3.8 4 0 0 4 4 4 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 ORY10684.1 - 3.5e-21 75.8 0.2 6.5e-21 74.9 0.2 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA zf-FPG_IleRS PF06827.14 ORY10684.1 - 0.00084 19.1 4.0 0.0018 18.1 4.0 1.6 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS tRNA-synt_1e PF01406.19 ORY10684.1 - 0.01 15.2 0.0 2.7 7.3 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain UPF0183 PF03676.14 ORY10685.1 - 1.2e-49 169.6 0.0 1.2e-32 113.7 0.0 3.4 3 1 0 3 3 3 3 Uncharacterised protein family (UPF0183) Kinesin PF00225.23 ORY10686.1 - 5.5e-111 370.7 0.1 5.5e-111 370.7 0.1 2.5 3 1 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 ORY10686.1 - 5.4e-27 94.6 0.2 4e-26 91.7 0.0 2.6 2 0 0 2 2 2 1 Microtubule binding Microtub_bind PF13931.6 ORY10686.1 - 5.4e-07 30.1 0.0 5.4e-07 30.1 0.0 5.0 5 0 0 5 5 5 1 Kinesin-associated microtubule-binding Phe_tRNA-synt_N PF02912.18 ORY10686.1 - 0.15 12.0 2.2 0.42 10.6 0.2 2.9 2 0 0 2 2 2 0 Aminoacyl tRNA synthetase class II, N-terminal domain ADH_N PF08240.12 ORY10688.1 - 2.9e-25 88.3 0.1 9.7e-25 86.6 0.0 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORY10688.1 - 9.9e-22 77.3 3.6 1.5e-21 76.7 3.6 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ORY10688.1 - 1.3e-07 32.8 0.1 2e-07 32.1 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Aldedh PF00171.22 ORY10689.1 - 1.1e-34 119.8 0.0 1.2e-34 119.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Mem_trans PF03547.18 ORY10708.1 - 3.8e-17 61.8 6.6 3.4e-16 58.6 6.6 2.0 1 1 0 1 1 1 1 Membrane transport protein ApbA_C PF08546.11 ORY10710.1 - 1.6e-36 125.2 0.2 2.8e-36 124.5 0.2 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 ORY10710.1 - 1.2e-27 96.4 0.0 2.8e-27 95.2 0.0 1.6 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.23 ORY10710.1 - 0.00022 21.2 0.0 0.00055 20.0 0.0 1.6 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Peptidase_M48 PF01435.18 ORY10711.1 - 4.6e-36 124.4 0.4 9.6e-36 123.4 0.4 1.5 1 1 0 1 1 1 1 Peptidase family M48 DUF2268 PF10026.9 ORY10711.1 - 0.069 12.7 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) Peptidase_M78 PF06114.13 ORY10711.1 - 0.11 12.4 0.3 0.24 11.3 0.1 1.7 2 0 0 2 2 2 0 IrrE N-terminal-like domain PH_10 PF15411.6 ORY10712.1 - 4.2e-29 101.3 0.0 9.1e-29 100.2 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain VWA PF00092.28 ORY10712.1 - 9.7e-14 52.0 0.0 1.5e-13 51.4 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 ORY10712.1 - 6.1e-08 32.8 0.1 3.7e-07 30.2 0.1 2.2 1 1 0 1 1 1 1 von Willebrand factor type A domain zf-RING_2 PF13639.6 ORY10712.1 - 1.4e-05 25.3 5.7 2.8e-05 24.3 5.7 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 ORY10712.1 - 0.00012 22.0 5.8 0.00021 21.2 5.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 ORY10712.1 - 0.00056 19.5 2.4 0.00056 19.5 2.4 2.2 3 0 0 3 3 2 1 Zinc-ribbon, C4HC2 type zf-C3HC4_2 PF13923.6 ORY10712.1 - 0.00079 19.2 5.0 0.0016 18.3 5.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 ORY10712.1 - 0.0021 17.9 2.6 0.0041 16.9 2.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORY10712.1 - 0.0031 17.3 5.5 0.007 16.2 5.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 ORY10712.1 - 0.0052 17.0 3.4 0.012 15.9 3.4 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING-like PF08746.11 ORY10712.1 - 0.0066 16.7 5.2 0.013 15.8 5.2 1.5 1 0 0 1 1 1 1 RING-like domain zf-RING_11 PF17123.5 ORY10712.1 - 0.021 14.6 2.6 0.043 13.6 2.6 1.6 1 0 0 1 1 1 0 RING-like zinc finger zf-UDP PF14569.6 ORY10712.1 - 0.11 12.7 0.5 0.2 11.8 0.5 1.3 1 0 0 1 1 1 0 Zinc-binding RING-finger PH PF00169.29 ORY10712.1 - 0.13 12.8 0.0 0.36 11.3 0.0 1.7 1 0 0 1 1 1 0 PH domain Prok-RING_4 PF14447.6 ORY10712.1 - 0.3 11.0 3.7 0.58 10.1 3.7 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 ORY10712.1 - 0.3 11.1 5.6 0.78 9.8 5.6 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_4 PF14570.6 ORY10712.1 - 1.1 9.0 3.2 2.1 8.2 3.2 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain CAP59_mtransfer PF11735.8 ORY10715.1 - 1.9e-66 224.2 0.0 2.4e-66 223.9 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 MepB PF08877.10 ORY10715.1 - 0.073 12.8 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 MepB protein Zip PF02535.22 ORY10717.1 - 3.2e-24 85.8 8.5 9.4e-17 61.2 5.2 2.1 2 0 0 2 2 2 2 ZIP Zinc transporter DUF2530 PF10745.9 ORY10717.1 - 2.4 8.4 8.7 19 5.6 0.5 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2530) PX PF00787.24 ORY10718.1 - 3.3e-18 65.7 0.0 1.6e-17 63.5 0.0 2.2 2 0 0 2 2 2 1 PX domain Vps5 PF09325.10 ORY10718.1 - 2.4e-07 30.6 14.9 0.00049 19.7 4.2 2.1 2 0 0 2 2 2 2 Vps5 C terminal like Peptidase_C10 PF01640.17 ORY10718.1 - 0.048 14.0 0.1 0.098 13.0 0.1 1.5 1 0 0 1 1 1 0 Peptidase C10 family DUF4083 PF13314.6 ORY10720.1 - 1.6 8.7 2.8 2.9 7.9 2.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) Utp12 PF04003.12 ORY10721.1 - 0.0045 17.3 0.3 1.6 9.1 0.1 2.5 2 0 0 2 2 2 2 Dip2/Utp12 Family HEAT_2 PF13646.6 ORY10721.1 - 0.1 13.0 0.2 3.6 8.1 0.1 3.3 2 1 1 3 3 3 0 HEAT repeats HEAT PF02985.22 ORY10721.1 - 0.12 12.7 1.6 28 5.3 0.0 4.2 4 0 0 4 4 4 0 HEAT repeat Toxin_TOLIP PF00087.21 ORY10724.1 - 0.64 10.3 11.1 0.058 13.7 3.3 2.6 2 1 0 2 2 2 0 Snake toxin and toxin-like protein DUF4188 PF13826.6 ORY10725.1 - 3.7e-24 85.3 0.0 6.3e-24 84.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4188) Dehydratase_hem PF13816.6 ORY10725.1 - 0.00041 19.8 0.2 0.00053 19.5 0.2 1.1 1 0 0 1 1 1 1 Haem-containing dehydratase MFS_1 PF07690.16 ORY10726.1 - 8.7e-30 103.8 51.5 2.5e-29 102.3 51.5 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans PF04082.18 ORY10727.1 - 1.4e-05 24.2 0.1 2.4e-05 23.5 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY10727.1 - 0.021 14.9 8.4 0.045 13.9 8.4 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3500 PF12006.8 ORY10728.1 - 1.2e-101 340.2 0.0 1.7e-101 339.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3500) LTXXQ PF07813.12 ORY10728.1 - 0.022 15.5 0.2 1.7 9.4 0.1 2.4 2 0 0 2 2 2 0 LTXXQ motif family protein B12-binding PF02310.19 ORY10729.1 - 0.012 15.6 0.0 0.017 15.1 0.0 1.2 1 0 0 1 1 1 0 B12 binding domain RecT PF03837.14 ORY10729.1 - 0.11 12.0 0.1 0.13 11.7 0.1 1.1 1 0 0 1 1 1 0 RecT family Tannase PF07519.11 ORY10730.1 - 4.1e-107 359.0 0.3 4.9e-107 358.7 0.3 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase FAD_binding_3 PF01494.19 ORY10731.1 - 3.3e-20 72.6 0.4 2e-19 70.1 0.4 1.9 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 ORY10731.1 - 3.1e-07 30.5 0.6 6e-07 29.6 0.6 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ORY10731.1 - 2.7e-05 23.6 0.1 0.00083 18.7 0.1 2.3 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ORY10731.1 - 0.00063 18.9 1.0 0.0012 18.0 1.0 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 ORY10731.1 - 0.0011 18.6 2.6 0.0022 17.7 1.9 1.8 1 1 1 2 2 2 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 ORY10731.1 - 0.059 12.2 0.2 0.11 11.3 0.2 1.4 1 0 0 1 1 1 0 Tryptophan halogenase Amino_oxidase PF01593.24 ORY10731.1 - 0.085 12.1 0.2 0.085 12.1 0.2 1.6 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase SE PF08491.10 ORY10731.1 - 0.11 11.6 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Squalene epoxidase Pyr_redox_3 PF13738.6 ORY10731.1 - 0.12 11.6 1.0 0.18 11.1 0.4 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase PAPA-1 PF04795.12 ORY10731.1 - 0.18 12.6 0.8 0.39 11.6 0.4 1.7 2 0 0 2 2 2 0 PAPA-1-like conserved region MFS_1 PF07690.16 ORY10732.1 - 3.3e-11 42.7 5.9 3.3e-11 42.7 5.9 3.1 3 1 1 4 4 4 2 Major Facilitator Superfamily VanZ PF04892.12 ORY10732.1 - 0.76 10.4 5.9 0.16 12.6 0.9 2.4 2 2 0 2 2 2 0 VanZ like family Esterase PF00756.20 ORY10733.1 - 0.11 12.2 0.1 0.17 11.5 0.1 1.2 1 0 0 1 1 1 0 Putative esterase Abhydrolase_1 PF00561.20 ORY10734.1 - 1.4e-05 24.8 0.0 2.7e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORY10734.1 - 3.5e-05 24.5 1.7 0.00035 21.2 0.1 2.7 2 1 0 2 2 2 1 Alpha/beta hydrolase family PGAP1 PF07819.13 ORY10734.1 - 0.018 14.7 0.3 0.24 11.1 0.0 2.1 2 0 0 2 2 2 0 PGAP1-like protein Ser_hydrolase PF06821.13 ORY10734.1 - 0.13 12.1 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase COesterase PF00135.28 ORY10735.1 - 3.2e-97 326.5 0.0 4.3e-97 326.1 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 ORY10735.1 - 4.2e-06 26.8 0.2 2.5e-05 24.2 0.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 ORY10735.1 - 0.00065 19.2 0.0 0.0011 18.5 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 ORY10735.1 - 0.06 13.0 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Putative esterase FAD_binding_4 PF01565.23 ORY10736.1 - 6.6e-24 84.2 3.8 1.1e-23 83.5 3.8 1.4 1 0 0 1 1 1 1 FAD binding domain PAP_assoc PF03828.19 ORY10737.1 - 8.5e-18 64.3 0.0 2e-17 63.1 0.0 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 ORY10737.1 - 1.3e-08 35.0 0.1 4.3e-08 33.4 0.0 1.9 2 0 0 2 2 2 1 Nucleotidyltransferase domain Polbeta PF18765.1 ORY10737.1 - 0.028 14.5 0.0 0.072 13.2 0.0 1.6 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase Isochorismatase PF00857.20 ORY10738.1 - 1e-28 100.7 0.0 1.5e-28 100.2 0.0 1.2 1 0 0 1 1 1 1 Isochorismatase family Acetate_kinase PF00871.17 ORY10739.1 - 1.7e-98 329.9 0.0 2e-98 329.7 0.0 1.0 1 0 0 1 1 1 1 Acetokinase family TACC_C PF05010.14 ORY10739.1 - 0.13 12.0 0.0 0.22 11.3 0.0 1.2 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Tyrosinase PF00264.20 ORY10740.1 - 7.2e-40 137.6 0.4 3.7e-39 135.3 0.4 1.9 1 1 0 1 1 1 1 Common central domain of tyrosinase MAPEG PF01124.18 ORY10742.1 - 4.9e-21 75.0 4.8 5.6e-21 74.8 4.8 1.1 1 0 0 1 1 1 1 MAPEG family DHFR_1 PF00186.19 ORY10743.1 - 3.8e-22 78.7 0.0 1.3e-15 57.5 0.0 3.0 2 1 0 2 2 2 2 Dihydrofolate reductase SMK-1 PF04802.15 ORY10744.1 - 1.8e-79 266.1 2.6 3.5e-79 265.1 2.6 1.5 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 MBOAT PF03062.19 ORY10746.1 - 1.1e-22 80.8 14.0 2.1e-22 80.0 14.0 1.4 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 ORY10746.1 - 8.2e-06 26.0 0.3 2.7e-05 24.3 0.3 1.9 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family WD40 PF00400.32 ORY10747.1 - 4.7e-29 100.0 20.6 9.9e-07 29.4 0.8 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY10747.1 - 2.9e-11 43.5 0.3 0.0048 17.2 0.1 4.9 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ORY10747.1 - 0.03 14.2 0.1 2.3 8.1 0.1 2.7 1 1 2 3 3 3 0 Eukaryotic translation initiation factor eIF2A Med22 PF06179.12 ORY10748.1 - 1.7e-12 47.5 0.0 2.2e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex PHD PF00628.29 ORY10749.1 - 5.9e-05 22.9 12.9 0.00011 22.1 12.9 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 ORY10749.1 - 0.025 14.1 8.7 0.049 13.2 8.7 1.4 1 0 0 1 1 1 0 PHD-finger Sacchrp_dh_NADP PF03435.18 ORY10750.1 - 1.5e-17 64.1 0.0 2.1e-17 63.6 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain DUF1428 PF07237.11 ORY10750.1 - 0.12 12.7 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1428) SLC35F PF06027.12 ORY10751.1 - 2.9e-98 329.1 23.7 3.4e-98 328.9 23.7 1.0 1 0 0 1 1 1 1 Solute carrier family 35 CRT-like PF08627.10 ORY10751.1 - 1.3e-10 40.8 6.8 1.8e-10 40.3 6.8 1.2 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 ORY10751.1 - 0.0009 19.4 35.3 0.013 15.7 13.9 2.5 2 1 0 2 2 2 2 EamA-like transporter family FUSC-like PF12805.7 ORY10751.1 - 2.6 7.0 8.0 0.41 9.7 2.8 2.2 2 1 0 2 2 2 0 FUSC-like inner membrane protein yccS DUF3487 PF11990.8 ORY10751.1 - 3 7.8 7.3 12 5.8 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3487) HCV_env PF01539.17 ORY10751.1 - 4.1 7.0 7.4 0.29 10.8 2.3 1.6 2 0 0 2 2 2 0 Hepatitis C virus envelope glycoprotein E1 eIF-5_eIF-2B PF01873.17 ORY10752.1 - 5e-40 136.0 0.0 1e-39 135.0 0.0 1.5 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.18 ORY10752.1 - 2.7e-19 69.1 0.3 2.7e-19 69.1 0.3 2.5 3 0 0 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon baeRF_family12 PF18856.1 ORY10752.1 - 1.4 9.5 5.9 9.5 6.8 0.0 2.3 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 12 HK PF02110.15 ORY10753.1 - 6.6e-65 218.9 2.4 6.6e-65 218.9 2.4 1.8 2 0 0 2 2 2 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.17 ORY10753.1 - 6e-56 188.6 1.2 1.1e-55 187.8 1.2 1.5 1 0 0 1 1 1 1 Thiamine monophosphate synthase Amidase PF01425.21 ORY10754.1 - 5.1e-54 183.9 0.0 6.1e-53 180.4 0.0 2.0 1 1 1 2 2 2 2 Amidase Vps5 PF09325.10 ORY10756.1 - 6.3e-11 42.3 7.2 9.7e-11 41.7 7.2 1.2 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 ORY10756.1 - 4.3e-07 29.9 0.0 8.6e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 PX domain BAR_3_WASP_bdg PF10456.9 ORY10756.1 - 0.055 12.9 1.6 0.1 12.1 1.6 1.3 1 0 0 1 1 1 0 WASP-binding domain of Sorting nexin protein NST1 PF13945.6 ORY10756.1 - 2.5 8.1 10.4 0.04 14.0 2.7 1.8 2 0 0 2 2 2 0 Salt tolerance down-regulator GTP_EFTU PF00009.27 ORY10757.1 - 1.4e-55 187.8 0.0 2.2e-55 187.3 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 ORY10757.1 - 3.5e-23 81.5 0.0 6.6e-23 80.6 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 ORY10757.1 - 2.9e-16 59.2 0.0 2.2e-08 34.0 0.0 2.5 2 0 0 2 2 2 2 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 ORY10757.1 - 1.1e-07 32.2 0.0 4e-07 30.3 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_IV PF03764.18 ORY10757.1 - 1.5e-05 24.8 0.1 0.0001 22.0 0.0 2.2 2 0 0 2 2 2 1 Elongation factor G, domain IV RF3_C PF16658.5 ORY10757.1 - 5.7e-05 22.9 0.0 0.00012 21.9 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain Zn_clus PF00172.18 ORY10758.1 - 1.1e-05 25.4 14.6 2.2e-05 24.5 14.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2428 PF10350.9 ORY10759.1 - 2.2e-69 233.8 1.0 5.4e-69 232.5 0.2 2.0 2 0 0 2 2 2 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.22 ORY10759.1 - 3.5e-05 23.7 1.4 39 4.9 0.2 6.5 5 1 1 6 6 6 1 HEAT repeat TetR_C_31 PF17940.1 ORY10759.1 - 0.46 10.7 4.5 0.21 11.8 1.2 2.2 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain DUF829 PF05705.14 ORY10762.1 - 5.4e-49 167.3 0.0 6.2e-49 167.1 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Ceramidase PF05875.12 ORY10763.1 - 0.013 14.9 0.2 0.023 14.1 0.1 1.5 1 1 0 1 1 1 0 Ceramidase FAD_binding_4 PF01565.23 ORY10764.1 - 4.3e-20 71.9 0.1 1.8e-19 69.9 0.2 2.0 2 1 0 2 2 2 1 FAD binding domain PTR2 PF00854.21 ORY10765.1 - 9.1e-39 133.4 13.5 1.6e-32 112.9 10.8 3.5 1 1 1 2 2 2 2 POT family AMP-binding PF00501.28 ORY10766.1 - 3.5e-58 197.2 0.0 4.7e-58 196.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORY10766.1 - 2.6e-07 31.5 0.0 7.9e-07 30.0 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AAA_35 PF14516.6 ORY10766.1 - 0.19 10.5 0.0 0.31 9.9 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain Ycf9 PF01737.17 ORY10766.1 - 2.2 8.2 4.1 0.39 10.6 0.4 1.7 2 0 0 2 2 2 0 YCF9 DAHP_synth_2 PF01474.16 ORY10767.1 - 2e-105 352.9 0.0 1.3e-57 195.3 0.0 2.0 1 1 1 2 2 2 2 Class-II DAHP synthetase family HTH_15 PF12324.8 ORY10767.1 - 0.013 15.5 0.4 6.3 6.8 0.0 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain of alkylmercury lyase ABC2_membrane PF01061.24 ORY10768.1 - 1.3e-16 60.6 11.9 1.8e-16 60.2 11.9 1.1 1 0 0 1 1 1 1 ABC-2 type transporter PRA1 PF03208.19 ORY10768.1 - 0.13 11.8 1.9 0.25 11.0 1.9 1.4 1 0 0 1 1 1 0 PRA1 family protein MFS_1 PF07690.16 ORY10781.1 - 1.2e-48 165.9 14.6 1.2e-48 165.9 14.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY10781.1 - 1.6e-08 33.8 2.4 1.6e-08 33.8 2.4 2.7 2 1 1 3 3 3 2 Sugar (and other) transporter OATP PF03137.20 ORY10781.1 - 0.00018 19.9 1.5 0.0064 14.8 1.5 2.5 1 1 1 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family TRI12 PF06609.13 ORY10781.1 - 0.00042 18.9 3.7 0.00069 18.2 3.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) SVM_signal PF12113.8 ORY10781.1 - 0.2 11.6 6.2 7.8 6.5 0.1 2.6 2 0 0 2 2 2 0 SVM protein signal sequence Zn_clus PF00172.18 ORY10782.1 - 3.5e-08 33.4 7.5 6.4e-08 32.6 7.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF973 PF06157.11 ORY10785.1 - 0.024 13.7 0.4 0.038 13.0 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF973) LrgA PF03788.14 ORY10785.1 - 0.45 10.5 7.8 0.86 9.6 7.8 1.5 1 0 0 1 1 1 0 LrgA family DUF2614 PF11023.8 ORY10785.1 - 7 6.8 9.9 6.7 6.9 0.9 2.6 2 1 1 3 3 3 0 Zinc-ribbon containing domain F-box PF00646.33 ORY10786.1 - 0.0021 17.9 0.2 0.0082 16.0 0.2 2.0 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 ORY10786.1 - 0.0046 16.8 1.8 0.005 16.7 0.2 1.9 2 0 0 2 2 2 1 F-box-like GFO_IDH_MocA PF01408.22 ORY10787.1 - 3.7e-15 56.8 0.0 6.3e-15 56.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 ORY10787.1 - 0.023 15.3 0.0 0.039 14.6 0.0 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Formyl_trans_N PF00551.19 ORY10788.1 - 2.8e-38 131.5 0.4 3.5e-38 131.1 0.4 1.1 1 0 0 1 1 1 1 Formyl transferase ACT PF01842.25 ORY10788.1 - 6.1e-11 41.9 0.0 3.4e-10 39.5 0.0 2.2 2 0 0 2 2 2 1 ACT domain ACT_6 PF13740.6 ORY10788.1 - 2.5e-07 30.6 0.0 9.2e-07 28.8 0.0 1.9 2 0 0 2 2 2 1 ACT domain MGS PF02142.22 ORY10788.1 - 0.089 13.0 0.1 0.19 12.0 0.1 1.5 1 0 0 1 1 1 0 MGS-like domain Stig1 PF04885.13 ORY10790.1 - 1.7e-27 96.6 142.7 3e-05 24.5 22.7 7.3 1 1 4 6 6 6 6 Stigma-specific protein, Stig1 EB PF01683.18 ORY10790.1 - 0.009 16.3 42.0 0.021 15.1 23.9 8.5 4 2 4 8 8 8 4 EB module Fer4 PF00037.27 ORY10790.1 - 0.045 13.6 3.1 0.045 13.6 3.1 12.2 15 0 0 15 15 15 0 4Fe-4S binding domain Fer4_3 PF12798.7 ORY10790.1 - 0.12 13.3 1.7 0.12 13.3 1.7 15.0 12 7 2 14 14 14 0 4Fe-4S binding domain Adeno_PIX PF03955.14 ORY10790.1 - 0.18 12.0 2.3 0.4 10.9 2.3 1.6 1 0 0 1 1 1 0 Adenovirus hexon-associated protein (IX) DUF1707 PF08044.11 ORY10794.1 - 0.058 13.5 0.2 0.15 12.1 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1707) CdvA PF18822.1 ORY10794.1 - 0.066 13.0 3.9 3.2 7.6 0.8 2.4 2 0 0 2 2 2 0 CdvA-like coiled-coil domain ACC_central PF08326.12 ORY10794.1 - 0.22 9.7 3.7 0.22 9.7 3.0 1.2 1 1 0 1 1 1 0 Acetyl-CoA carboxylase, central region DUF4865 PF16157.5 ORY10794.1 - 0.58 10.1 2.4 1.9 8.5 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4865) ZapD PF07072.11 ORY10794.1 - 0.81 9.4 5.6 3.1 7.5 1.3 2.1 2 0 0 2 2 2 0 Cell division protein XhlA PF10779.9 ORY10794.1 - 1.6 9.0 7.8 2.5 8.4 1.4 3.0 2 2 0 2 2 2 0 Haemolysin XhlA Acetyltransf_18 PF18014.1 ORY10800.1 - 0.039 13.8 0.0 0.79 9.6 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain GPI-anchored PF10342.9 ORY10800.1 - 0.045 14.5 0.9 3.6 8.4 0.0 2.8 3 0 0 3 3 3 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family tRNA-synt_1 PF00133.22 ORY10801.1 - 1e-223 744.0 0.0 1.5e-223 743.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 ORY10801.1 - 1.6e-25 89.9 0.0 5.6e-25 88.1 0.0 1.9 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 ORY10801.1 - 1.2e-14 53.9 0.1 3.5e-05 22.7 0.0 4.0 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 ORY10801.1 - 0.033 13.5 0.1 0.15 11.3 0.0 2.0 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain CX9C PF16860.5 ORY10802.1 - 0.0025 17.8 0.9 0.0033 17.4 0.9 1.1 1 0 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, NDUF_B7 PF05676.13 ORY10802.1 - 0.011 15.4 0.8 0.48 10.2 0.0 2.0 1 1 1 2 2 2 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Sfi1 PF08457.10 ORY10803.1 - 8.3e-165 549.6 86.4 2.7e-161 538.0 81.0 2.1 1 1 1 2 2 2 2 Sfi1 spindle body protein Pkinase PF00069.25 ORY10807.1 - 3.9e-22 78.9 0.0 2.6e-20 72.9 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORY10807.1 - 1.5e-17 63.8 0.0 2.3e-14 53.3 0.0 2.6 2 1 0 2 2 2 2 Protein tyrosine kinase TPR_12 PF13424.6 ORY10808.1 - 5.4e-54 180.4 40.9 1.6e-14 53.9 1.9 10.9 11 0 0 11 11 11 8 Tetratricopeptide repeat TPR_10 PF13374.6 ORY10808.1 - 1.6e-27 94.6 38.3 4.8e-06 26.3 0.1 14.4 16 0 0 16 16 16 5 Tetratricopeptide repeat TPR_MalT PF17874.1 ORY10808.1 - 3.7e-15 56.1 29.2 2.7e-08 33.6 8.2 3.7 2 1 1 4 4 4 3 MalT-like TPR region TPR_19 PF14559.6 ORY10808.1 - 1.5e-11 44.6 25.8 0.35 11.4 0.0 10.3 5 4 4 11 11 11 5 Tetratricopeptide repeat TPR_7 PF13176.6 ORY10808.1 - 2.9e-11 42.6 25.7 0.67 10.1 0.0 11.6 13 0 0 13 13 13 4 Tetratricopeptide repeat TPR_2 PF07719.17 ORY10808.1 - 4.4e-11 42.0 23.5 0.072 13.2 0.4 11.1 13 0 0 13 13 11 3 Tetratricopeptide repeat Pkinase PF00069.25 ORY10808.1 - 2e-09 37.2 0.0 4.5e-08 32.8 0.0 2.3 1 1 1 2 2 2 1 Protein kinase domain TPR_8 PF13181.6 ORY10808.1 - 4.4e-08 32.7 18.3 0.16 12.2 0.2 9.9 12 0 0 12 12 9 2 Tetratricopeptide repeat TPR_17 PF13431.6 ORY10808.1 - 1.4e-05 25.1 7.3 12 6.6 0.0 8.8 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_4 PF07721.14 ORY10808.1 - 2.2e-05 24.6 15.5 0.26 12.0 0.0 7.6 8 0 0 8 8 6 1 Tetratricopeptide repeat PPR PF01535.20 ORY10808.1 - 0.00018 21.5 0.3 1.9 8.9 0.0 5.0 4 0 0 4 4 4 1 PPR repeat ANAPC3 PF12895.7 ORY10808.1 - 0.00021 21.5 10.3 3.4 8.0 0.2 7.5 5 3 3 8 8 7 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 ORY10808.1 - 0.00035 20.2 10.7 19 5.3 0.0 8.4 9 0 0 9 9 9 0 Tetratricopeptide repeat Pkinase_Tyr PF07714.17 ORY10808.1 - 0.00045 19.6 0.0 0.025 13.9 0.0 2.4 1 1 1 2 2 2 1 Protein tyrosine kinase TPR_14 PF13428.6 ORY10808.1 - 0.022 15.6 29.1 1.3 10.1 0.6 10.4 9 3 4 13 13 10 0 Tetratricopeptide repeat Kdo PF06293.14 ORY10808.1 - 0.031 13.6 0.0 0.071 12.5 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TPR_16 PF13432.6 ORY10808.1 - 0.039 14.6 20.2 0.22 12.2 0.6 7.6 8 2 1 9 9 8 0 Tetratricopeptide repeat CinA_KH PF18146.1 ORY10808.1 - 0.22 11.7 1.0 0.81 9.9 0.1 2.5 2 0 0 2 2 2 0 Damage-inducible protein CinA KH domain FAT PF02259.23 ORY10808.1 - 0.24 10.5 7.5 1.6 7.9 0.2 3.5 3 2 0 3 3 3 0 FAT domain TPR_20 PF14561.6 ORY10808.1 - 1.2 9.5 0.0 1.2 9.5 0.0 5.5 5 2 3 8 8 6 0 Tetratricopeptide repeat Pro_CA PF00484.19 ORY10809.1 - 2.9e-51 173.9 0.0 3.6e-51 173.6 0.0 1.1 1 0 0 1 1 1 1 Carbonic anhydrase DUF3253 PF11625.8 ORY10810.1 - 3.5e-23 81.6 0.0 4.1e-23 81.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3253) Pex24p PF06398.11 ORY10811.1 - 0.0027 16.8 9.4 0.0051 15.8 9.4 1.5 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF592 PF04574.13 ORY10811.1 - 0.16 11.7 0.2 0.51 10.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF592) EcsB PF05975.12 ORY10811.1 - 0.26 10.1 1.0 0.39 9.5 1.0 1.1 1 0 0 1 1 1 0 Bacterial ABC transporter protein EcsB Apolipoprotein PF01442.18 ORY10812.1 - 0.0091 15.9 4.1 0.012 15.5 4.1 1.1 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF3347 PF11827.8 ORY10812.1 - 0.065 13.4 3.1 0.084 13.0 3.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) DUF883 PF05957.13 ORY10812.1 - 0.16 12.6 6.8 0.088 13.4 4.2 1.8 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) V-ATPase_G PF03179.15 ORY10812.1 - 0.9 10.1 9.2 1.4 9.5 9.2 1.4 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit ATP-synt_B PF00430.18 ORY10812.1 - 5.7 7.0 11.0 18 5.4 11.0 1.7 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) Remorin_C PF03763.13 ORY10812.1 - 7.1 6.6 11.2 5.3 7.0 5.2 2.1 1 1 1 2 2 2 0 Remorin, C-terminal region CDT1_C PF16679.5 ORY10813.1 - 6.6e-17 61.7 0.0 1.3e-16 60.8 0.0 1.5 1 0 0 1 1 1 1 DNA replication factor Cdt1 C-terminal domain Lipase_GDSL_lke PF16255.5 ORY10813.1 - 0.14 11.5 0.0 0.68 9.3 0.0 1.9 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase Pkinase PF00069.25 ORY10814.1 - 1.4e-35 123.0 0.0 2.4e-35 122.2 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY10814.1 - 7.1e-25 87.8 0.0 3.1e-24 85.6 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase MecA PF05389.12 ORY10815.1 - 0.037 13.7 0.0 0.058 13.0 0.0 1.3 1 0 0 1 1 1 0 Negative regulator of genetic competence (MecA) HET PF06985.11 ORY10819.1 - 3.7e-06 27.4 0.0 4.4e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) AAA PF00004.29 ORY10820.1 - 3.7e-07 30.6 0.0 5.9e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 ORY10820.1 - 2.6e-05 24.7 0.0 4e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 ORY10820.1 - 0.00048 20.3 0.0 0.00067 19.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 ORY10820.1 - 0.0016 18.2 0.0 0.0031 17.3 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 ORY10820.1 - 0.0033 17.4 0.0 0.0061 16.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 ORY10820.1 - 0.0075 16.5 0.0 0.012 15.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 ORY10820.1 - 0.018 14.3 0.0 0.027 13.6 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain Mg_chelatase PF01078.21 ORY10820.1 - 0.035 13.5 0.1 0.058 12.8 0.1 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 ORY10820.1 - 0.15 11.8 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_11 PF13086.6 ORY10820.1 - 0.17 11.6 0.0 0.22 11.3 0.0 1.1 1 0 0 1 1 1 0 AAA domain Pterin_4a PF01329.19 ORY10822.1 - 1.1e-09 38.4 0.2 1.3e-09 38.1 0.2 1.1 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase Pentapeptide_4 PF13599.6 ORY10825.1 - 4e-11 42.9 0.0 0.021 15.0 0.0 4.4 1 1 4 5 5 5 5 Pentapeptide repeats (9 copies) Pentapeptide PF00805.22 ORY10825.1 - 0.014 15.0 0.0 37 4.1 0.0 5.0 6 0 0 6 6 6 0 Pentapeptide repeats (8 copies) Asp_protease_2 PF13650.6 ORY10825.1 - 0.13 12.9 7.5 89 3.8 0.1 5.1 1 1 5 6 6 6 0 Aspartyl protease gag-asp_proteas PF13975.6 ORY10825.1 - 0.6 10.7 20.3 12 6.6 0.5 5.6 1 1 5 6 6 6 0 gag-polyprotein putative aspartyl protease SKG6 PF08693.10 ORY10837.1 - 8.5e-09 34.7 1.7 1.8e-08 33.7 1.7 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain TMEM154 PF15102.6 ORY10837.1 - 0.00096 19.1 1.1 0.0045 16.9 1.1 2.3 1 1 0 1 1 1 1 TMEM154 protein family DUF4448 PF14610.6 ORY10837.1 - 0.0024 17.7 0.0 0.0041 16.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) CcmD PF04995.14 ORY10837.1 - 0.0033 17.5 0.6 0.0053 16.8 0.6 1.3 1 0 0 1 1 1 1 Heme exporter protein D (CcmD) CD34_antigen PF06365.12 ORY10837.1 - 0.0034 17.0 0.0 0.0053 16.4 0.0 1.3 1 0 0 1 1 1 1 CD34/Podocalyxin family PAP_PilO PF06864.12 ORY10837.1 - 0.041 12.7 0.0 0.041 12.7 0.0 2.0 2 1 1 3 3 3 0 Pilin accessory protein (PilO) Steroid_dh PF02544.16 ORY10838.1 - 7.7e-18 64.9 4.3 1.7e-17 63.8 0.8 2.5 2 1 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 ORY10838.1 - 0.012 15.2 2.6 0.02 14.4 2.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1295) NB-ARC PF00931.22 ORY10839.1 - 3.3e-05 23.2 0.0 6.1e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain PRK PF00485.18 ORY10839.1 - 0.0017 18.1 0.0 0.0027 17.5 0.0 1.4 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 ORY10839.1 - 0.0022 18.5 0.3 0.0048 17.4 0.2 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ORY10839.1 - 0.005 17.2 0.0 0.0093 16.4 0.0 1.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.6 ORY10839.1 - 0.0071 16.8 0.0 0.016 15.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 ORY10839.1 - 0.0092 15.1 0.0 0.017 14.2 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.6 ORY10839.1 - 0.0097 16.2 0.0 0.019 15.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 ORY10839.1 - 0.014 15.3 0.0 0.024 14.6 0.0 1.3 1 0 0 1 1 1 0 NTPase NACHT PF05729.12 ORY10839.1 - 0.014 15.3 0.0 0.029 14.3 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_30 PF13604.6 ORY10839.1 - 0.018 14.7 0.1 0.03 14.0 0.1 1.3 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 ORY10839.1 - 0.032 13.5 0.4 0.052 12.8 0.0 1.5 2 0 0 2 2 2 0 Zeta toxin AAA PF00004.29 ORY10839.1 - 0.032 14.7 0.0 0.05 14.0 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 ORY10839.1 - 0.046 13.9 1.1 0.058 13.6 0.1 1.6 2 0 0 2 2 2 0 AAA domain KTI12 PF08433.10 ORY10839.1 - 0.053 13.0 0.1 0.077 12.4 0.1 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 SRP54 PF00448.22 ORY10839.1 - 0.055 13.1 0.0 0.087 12.4 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Viral_helicase1 PF01443.18 ORY10839.1 - 0.065 13.0 0.1 0.095 12.4 0.1 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 ORY10839.1 - 0.095 11.9 0.1 0.14 11.4 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NCBP3 PF10309.9 ORY10840.1 - 3.6e-08 33.1 0.0 5.6e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 Aldedh PF00171.22 ORY10841.1 - 4.7e-158 526.5 0.0 5.3e-158 526.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family adh_short_C2 PF13561.6 ORY10842.1 - 8.2e-61 205.5 0.1 1e-60 205.2 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY10842.1 - 2.5e-50 170.6 0.2 3e-50 170.4 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORY10842.1 - 6.5e-05 22.9 0.1 0.00013 22.0 0.1 1.4 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 ORY10842.1 - 0.0036 17.2 0.2 0.0055 16.6 0.2 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 ORY10842.1 - 0.04 14.0 0.2 0.069 13.2 0.2 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Epimerase PF01370.21 ORY10842.1 - 0.1 12.1 0.5 0.16 11.4 0.1 1.7 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.6 ORY10844.1 - 2.3e-54 184.4 0.0 2.8e-54 184.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY10844.1 - 3.3e-43 147.4 0.0 4.3e-43 147.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORY10844.1 - 4.4e-10 39.8 0.0 6.5e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 ORY10844.1 - 0.019 14.3 0.0 0.028 13.8 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) HET PF06985.11 ORY10845.1 - 8.7e-23 81.3 0.2 2.7e-22 79.7 0.2 1.8 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF3176 PF11374.8 ORY10846.1 - 8.1e-27 93.5 0.4 8.1e-27 93.5 0.4 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) Syntaxin_2 PF14523.6 ORY10847.1 - 3.2e-26 91.6 1.5 3.2e-26 91.6 1.5 2.6 2 1 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.19 ORY10847.1 - 2.9e-15 56.0 4.9 3.2e-15 55.8 3.5 1.8 2 0 0 2 2 2 1 SNARE domain Synaptobrevin PF00957.21 ORY10847.1 - 9.2e-06 25.4 1.5 9.2e-06 25.4 1.5 2.8 3 0 0 3 3 3 1 Synaptobrevin Syntaxin PF00804.25 ORY10847.1 - 2.9e-05 23.8 15.7 0.00093 18.9 15.7 2.5 1 1 0 1 1 1 1 Syntaxin MCPsignal PF00015.21 ORY10847.1 - 0.021 14.7 5.0 0.22 11.3 2.1 2.5 2 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Nre_C PF04895.12 ORY10847.1 - 0.061 13.2 2.7 0.097 12.6 0.0 2.5 3 0 0 3 3 3 0 Archaeal Nre, C-terminal TMPIT PF07851.13 ORY10847.1 - 0.077 12.2 5.8 0.44 9.7 4.5 2.0 2 0 0 2 2 2 0 TMPIT-like protein DUF5345 PF17280.2 ORY10847.1 - 0.29 11.1 0.1 0.29 11.1 0.1 3.0 3 0 0 3 3 3 0 Family of unknown function (DUF5345) PMC2NT PF08066.12 ORY10847.1 - 0.39 11.4 3.6 1.1 10.1 0.1 2.7 2 1 0 2 2 2 0 PMC2NT (NUC016) domain CCDC53 PF10152.9 ORY10847.1 - 0.44 11.0 7.5 0.068 13.6 2.6 2.0 1 1 2 3 3 3 0 Subunit CCDC53 of WASH complex DUF1664 PF07889.12 ORY10847.1 - 0.64 10.1 6.2 17 5.4 2.8 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) DUF883 PF05957.13 ORY10847.1 - 0.77 10.4 12.0 4.4 8.0 3.1 3.1 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) Orf78 PF06024.12 ORY10847.1 - 1.7 9.0 6.0 0.32 11.3 0.7 2.2 2 0 0 2 2 2 0 Orf78 (ac78) DUF16 PF01519.16 ORY10847.1 - 4.3 7.9 14.4 1.3e+02 3.2 0.0 3.1 2 1 0 2 2 2 0 Protein of unknown function DUF16 Ndc1_Nup PF09531.10 ORY10848.1 - 5.9e-161 537.2 0.0 6.6e-161 537.1 0.0 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup DUF2175 PF09943.9 ORY10848.1 - 0.12 12.7 0.7 26 5.2 0.2 2.8 2 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) Pkinase PF00069.25 ORY10849.1 - 3.6e-14 52.8 0.0 9.2e-14 51.4 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY10849.1 - 3.3e-09 36.4 0.0 5.5e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT PF02985.22 ORY10849.1 - 1.9e-08 33.8 0.7 0.12 12.7 0.0 4.9 4 0 0 4 4 4 2 HEAT repeat Cnd1 PF12717.7 ORY10849.1 - 6.9e-07 29.4 0.1 7.2e-06 26.1 0.0 2.0 1 1 1 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Kinase-like PF14531.6 ORY10849.1 - 0.001 18.5 0.0 0.0018 17.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like HEAT_2 PF13646.6 ORY10849.1 - 0.0029 17.9 1.1 0.067 13.6 0.2 3.2 2 1 2 4 4 4 2 HEAT repeats HEAT_EZ PF13513.6 ORY10849.1 - 0.0049 17.3 0.1 9.5 6.8 0.1 3.4 4 0 0 4 4 4 2 HEAT-like repeat CLASP_N PF12348.8 ORY10849.1 - 0.14 11.7 0.1 10 5.6 0.0 2.6 1 1 2 3 3 3 0 CLASP N terminal Forkhead PF00250.18 ORY10850.1 - 1.7e-05 25.0 0.0 3.8e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Forkhead domain PHD PF00628.29 ORY10850.1 - 0.00063 19.6 6.6 0.00063 19.6 6.6 2.3 2 0 0 2 2 2 1 PHD-finger YCII PF03795.14 ORY10851.1 - 0.0022 18.3 0.0 0.0033 17.8 0.0 1.2 1 0 0 1 1 1 1 YCII-related domain Ribonuc_red_lgC PF02867.15 ORY10852.1 - 1.8e-188 627.3 0.0 2.3e-188 627.0 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 ORY10852.1 - 2.5e-25 88.3 0.1 5.4e-25 87.2 0.1 1.6 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 ORY10852.1 - 8.5e-17 61.5 0.0 2.3e-16 60.1 0.0 1.8 1 0 0 1 1 1 1 ATP cone domain PNRC PF15365.6 ORY10852.1 - 0.7 9.8 3.0 2 8.4 3.0 1.8 1 0 0 1 1 1 0 Proline-rich nuclear receptor coactivator motif Ribosomal_L17 PF01196.19 ORY10853.1 - 1.4e-33 115.6 0.6 2.1e-33 115.1 0.1 1.5 2 0 0 2 2 2 1 Ribosomal protein L17 Sec23_trunk PF04811.15 ORY10854.1 - 3.2e-77 259.4 0.0 4.9e-77 258.8 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 ORY10854.1 - 1.4e-29 102.7 0.1 3.2e-29 101.5 0.1 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 ORY10854.1 - 1e-21 76.6 0.2 2.8e-21 75.3 0.2 1.8 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 ORY10854.1 - 2.4e-15 56.3 3.5 4.7e-15 55.4 3.5 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 ORY10854.1 - 2.6e-12 46.4 0.0 1.5e-11 44.1 0.0 2.2 2 0 0 2 2 2 1 Gelsolin repeat Vps36-NZF-N PF16988.5 ORY10854.1 - 0.086 12.3 0.6 0.22 11.0 0.1 1.9 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain DUF2576 PF10845.8 ORY10854.1 - 0.18 11.4 0.5 0.44 10.2 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2576) Cupin_2 PF07883.11 ORY10855.1 - 9.5e-06 25.2 0.1 1.7e-05 24.5 0.1 1.4 1 0 0 1 1 1 1 Cupin domain Coa1 PF08695.10 ORY10856.1 - 1.6e-38 131.0 0.0 2e-38 130.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 Ost5 PF05251.12 ORY10856.1 - 0.23 11.7 1.3 0.34 11.2 1.3 1.2 1 0 0 1 1 1 0 Oligosaccharyltransferase subunit 5 BES1_N PF05687.13 ORY10857.1 - 0.047 14.1 0.8 0.088 13.2 0.8 1.4 1 0 0 1 1 1 0 BES1/BZR1 plant transcription factor, N-terminal DUF997 PF06196.12 ORY10857.1 - 0.13 12.3 3.6 1.5 8.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF997) 4F5 PF04419.14 ORY10858.1 - 1.1e-11 45.4 6.9 1.1e-11 45.4 6.9 1.7 2 0 0 2 2 2 1 4F5 protein family SMN PF06003.12 ORY10860.1 - 0.00056 19.2 3.8 0.00056 19.2 3.8 2.2 1 1 1 2 2 2 1 Survival motor neuron protein (SMN) PAS_4 PF08448.10 ORY10860.1 - 0.18 12.1 1.6 0.32 11.3 0.1 1.9 2 0 0 2 2 2 0 PAS fold RRM_1 PF00076.22 ORY10861.1 - 6.4e-13 48.3 0.0 1.8e-12 46.9 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 ORY10861.1 - 0.13 12.4 0.2 0.57 10.3 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif zf-C2H2 PF00096.26 ORY10863.1 - 5.5e-09 36.0 10.1 0.0073 16.7 0.2 4.2 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY10863.1 - 1.9e-06 28.2 6.4 0.077 13.9 0.2 4.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORY10863.1 - 0.095 13.2 2.4 20 5.9 0.0 3.9 3 0 0 3 3 3 0 Zinc-finger double domain zf-BED PF02892.15 ORY10863.1 - 0.14 12.2 0.6 0.4 10.8 0.6 1.8 1 0 0 1 1 1 0 BED zinc finger zf-C2H2_6 PF13912.6 ORY10863.1 - 0.43 10.6 2.9 39 4.4 1.7 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger zf-Di19 PF05605.12 ORY10863.1 - 0.56 10.6 8.3 0.28 11.5 0.8 2.8 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding Zn_clus PF00172.18 ORY10864.1 - 0.0016 18.6 4.7 0.003 17.6 4.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-met PF12874.7 ORY10865.1 - 0.00024 21.4 1.0 0.00024 21.4 1.0 4.0 5 0 0 5 5 5 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 ORY10865.1 - 0.00077 19.7 0.4 0.00077 19.7 0.4 2.5 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 ORY10865.1 - 0.0044 17.0 0.8 0.0044 17.0 0.8 3.7 4 0 0 4 4 4 1 C2H2-type zinc finger zf-C2HE PF16278.5 ORY10865.1 - 0.0091 16.4 0.5 4.9 7.7 0.2 2.8 2 0 0 2 2 2 2 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2 PF00096.26 ORY10865.1 - 0.037 14.5 1.0 0.037 14.5 1.0 4.0 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY10865.1 - 0.048 14.5 1.1 0.048 14.5 1.1 4.7 4 0 0 4 4 4 0 C2H2-type zinc finger zf-MYST PF17772.1 ORY10865.1 - 0.063 12.9 0.2 0.15 11.7 0.2 1.6 1 0 0 1 1 1 0 MYST family zinc finger domain zinc-ribbons_6 PF07191.12 ORY10865.1 - 3 7.9 10.9 4.7 7.3 0.4 3.4 3 0 0 3 3 3 0 zinc-ribbons DUF3611 PF12263.8 ORY10866.1 - 0.066 13.1 0.2 0.14 12.0 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3611) Kelch_5 PF13854.6 ORY10867.1 - 7.5e-13 48.1 15.5 6.5e-12 45.2 0.6 5.6 6 0 0 6 6 6 1 Kelch motif Kelch_4 PF13418.6 ORY10867.1 - 2.5e-08 33.8 13.2 0.0093 16.0 0.6 5.2 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_3 PF13415.6 ORY10867.1 - 0.00013 22.1 12.2 0.13 12.6 0.5 5.7 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_1 PF01344.25 ORY10867.1 - 0.00021 20.8 5.5 2 8.1 0.1 5.2 5 0 0 5 5 5 2 Kelch motif SKG6 PF08693.10 ORY10867.1 - 0.0022 17.3 0.4 0.0043 16.4 0.4 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain EphA2_TM PF14575.6 ORY10867.1 - 0.0035 18.2 0.1 0.014 16.3 0.0 2.0 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain Kelch_6 PF13964.6 ORY10867.1 - 0.0046 17.2 13.6 0.065 13.6 0.1 4.9 4 1 1 5 5 4 2 Kelch motif OAD_gamma PF04277.13 ORY10867.1 - 0.017 15.7 0.0 0.038 14.6 0.0 1.5 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain ECSCR PF15820.5 ORY10867.1 - 0.048 13.5 0.0 0.092 12.6 0.0 1.4 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator Syndecan PF01034.20 ORY10867.1 - 0.054 13.4 0.2 0.11 12.4 0.2 1.4 1 0 0 1 1 1 0 Syndecan domain Herpes_gE PF02480.16 ORY10867.1 - 0.08 11.7 0.1 0.12 11.1 0.1 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E WD40 PF00400.32 ORY10868.1 - 4.8e-26 90.5 11.0 4.8e-06 27.2 0.6 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY10868.1 - 1.9e-13 50.5 0.8 0.1 12.9 0.1 5.1 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ORY10868.1 - 0.001 19.0 0.0 0.083 12.8 0.0 2.3 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Lactonase PF10282.9 ORY10868.1 - 0.0055 16.0 0.0 0.045 13.0 0.0 2.3 2 1 1 3 3 3 1 Lactonase, 7-bladed beta-propeller Nup160 PF11715.8 ORY10868.1 - 0.023 13.4 0.1 2.1 6.9 0.1 2.3 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 ORY10868.1 - 0.043 12.3 0.0 0.94 7.9 0.0 2.0 1 1 1 2 2 2 0 Cytochrome D1 heme domain Ge1_WD40 PF16529.5 ORY10868.1 - 0.058 12.3 0.6 4 6.3 0.0 3.2 2 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Guanylate_kin PF00625.21 ORY10869.1 - 7.2e-60 201.8 0.0 8.3e-60 201.6 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_16 PF13191.6 ORY10869.1 - 1.7e-06 28.5 0.0 3.7e-06 27.4 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 ORY10869.1 - 1.9e-05 24.8 0.0 9.6e-05 22.6 0.0 2.1 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 ORY10869.1 - 5.8e-05 23.2 0.0 0.0001 22.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 ORY10869.1 - 0.0001 22.6 0.0 0.00032 21.0 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 ORY10869.1 - 0.00036 21.1 0.2 0.0013 19.3 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 ORY10869.1 - 0.00091 18.8 0.0 0.0015 18.1 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region T2SSE PF00437.20 ORY10869.1 - 0.00092 18.4 0.0 0.0021 17.2 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 ORY10869.1 - 0.0016 18.9 0.0 0.0022 18.5 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_28 PF13521.6 ORY10869.1 - 0.0017 18.6 0.1 0.0083 16.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 ORY10869.1 - 0.0019 18.0 0.0 0.12 12.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 ORY10869.1 - 0.0022 18.4 0.0 0.0048 17.3 0.0 1.6 2 0 0 2 2 1 1 RNA helicase NTPase_1 PF03266.15 ORY10869.1 - 0.0023 17.9 0.0 0.0038 17.1 0.0 1.4 1 0 0 1 1 1 1 NTPase Rad17 PF03215.15 ORY10869.1 - 0.0051 16.8 0.0 0.0084 16.0 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_29 PF13555.6 ORY10869.1 - 0.0065 16.2 0.1 0.012 15.4 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF2075 PF09848.9 ORY10869.1 - 0.0076 15.5 0.0 0.12 11.6 0.0 2.0 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) RsgA_GTPase PF03193.16 ORY10869.1 - 0.0094 15.9 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_30 PF13604.6 ORY10869.1 - 0.013 15.3 0.2 0.029 14.1 0.0 1.6 2 0 0 2 2 2 0 AAA domain Thymidylate_kin PF02223.17 ORY10869.1 - 0.014 15.1 0.6 1.5 8.5 0.6 2.4 1 1 0 1 1 1 0 Thymidylate kinase AAA PF00004.29 ORY10869.1 - 0.024 15.0 0.0 0.089 13.2 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 ORY10869.1 - 0.034 14.2 0.0 0.061 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 ORY10869.1 - 0.048 13.4 0.2 0.12 12.1 0.0 1.7 2 0 0 2 2 2 0 Cytidylate kinase Sigma54_activat PF00158.26 ORY10869.1 - 0.061 13.0 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain dNK PF01712.19 ORY10869.1 - 0.075 12.9 0.1 0.74 9.6 0.0 2.1 2 0 0 2 2 2 0 Deoxynucleoside kinase AAA_5 PF07728.14 ORY10869.1 - 0.08 12.9 0.0 0.5 10.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 ORY10869.1 - 0.089 12.7 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 NACHT domain KAP_NTPase PF07693.14 ORY10869.1 - 0.097 11.9 0.0 0.23 10.6 0.0 1.5 1 1 0 2 2 2 0 KAP family P-loop domain ATPase_2 PF01637.18 ORY10869.1 - 0.099 12.5 0.1 0.19 11.6 0.0 1.6 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_19 PF13245.6 ORY10869.1 - 0.11 12.8 0.0 0.22 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 ORY10869.1 - 0.15 12.5 2.0 0.16 12.5 0.5 1.6 1 1 0 1 1 1 0 AAA domain WD40 PF00400.32 ORY10870.1 - 1.3e-18 66.9 8.4 0.00064 20.5 0.0 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY10870.1 - 8.7e-11 42.0 0.0 6.7e-06 26.3 0.0 4.3 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 ORY10870.1 - 0.2 11.0 0.0 0.27 10.5 0.0 1.3 1 0 0 1 1 1 0 WD40-like domain Peptidase_S10 PF00450.22 ORY10871.1 - 2.2e-114 383.2 0.0 3e-114 382.7 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Rad52_Rad22 PF04098.15 ORY10871.1 - 1.6e-59 200.3 0.1 2.5e-59 199.6 0.1 1.3 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein DUF4448 PF14610.6 ORY10871.1 - 0.14 11.9 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) RNA_Me_trans PF04252.13 ORY10872.1 - 3.8e-84 281.3 0.0 4.3e-84 281.1 0.0 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase Endosulfine PF04667.17 ORY10874.1 - 2.4e-30 104.5 0.1 4.2e-30 103.7 0.1 1.4 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region UPF0160 PF03690.13 ORY10875.1 - 3.4e-112 375.2 0.0 2.7e-111 372.2 0.0 1.9 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0160) UB2H PF14814.6 ORY10875.1 - 0.13 12.3 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 Bifunctional transglycosylase second domain ICE2 PF08426.10 ORY10876.1 - 2.8e-153 510.8 3.6 3.2e-153 510.7 3.6 1.0 1 0 0 1 1 1 1 ICE2 zf-C2H2 PF00096.26 ORY10878.1 - 0.51 10.9 12.8 3.4 8.3 0.0 4.0 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY10878.1 - 1.2 10.2 13.5 10 7.3 0.1 4.0 4 0 0 4 4 4 0 C2H2-type zinc finger YkyA PF10368.9 ORY10879.1 - 0.016 14.9 1.3 0.027 14.2 1.3 1.3 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein SNF2_N PF00176.23 ORY10880.1 - 1.3e-20 73.5 0.1 6.1e-15 54.8 0.0 2.2 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 ORY10880.1 - 4.4e-13 49.5 0.0 1.2e-12 48.1 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 ORY10880.1 - 0.084 12.1 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Hexapep PF00132.24 ORY10882.1 - 1.6e-11 43.5 4.0 1.4e-08 34.1 1.9 3.2 2 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Mac PF12464.8 ORY10882.1 - 3.2e-11 43.3 1.2 4e-11 43.0 0.0 1.8 2 0 0 2 2 2 1 Maltose acetyltransferase Hexapep_2 PF14602.6 ORY10882.1 - 6.4e-09 35.4 2.7 2.9e-07 30.1 2.1 3.0 3 0 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase Zn_clus PF00172.18 ORY10882.1 - 2.5e-08 33.9 9.0 4.6e-08 33.0 9.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_L3 PF00297.22 ORY10883.1 - 1.9e-16 60.0 4.6 2.1e-13 50.0 2.2 2.1 1 1 1 2 2 2 2 Ribosomal protein L3 PHO4 PF01384.20 ORY10885.1 - 0.0014 17.7 1.3 0.0021 17.1 1.3 1.4 1 1 0 1 1 1 1 Phosphate transporter family ALAD PF00490.21 ORY10886.1 - 3.8e-121 404.1 0.0 4.6e-121 403.9 0.0 1.1 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase NOA36 PF06524.12 ORY10887.1 - 3.5 6.8 7.7 4.6 6.5 7.7 1.2 1 0 0 1 1 1 0 NOA36 protein DUF4286 PF14114.6 ORY10889.1 - 0.022 15.2 0.3 3.6 8.2 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4286) DUF3899 PF13038.6 ORY10890.1 - 0.078 13.5 0.0 0.5 10.9 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) PBP3 PF18056.1 ORY10891.1 - 0.12 12.5 0.0 1.3 9.2 0.0 2.3 2 0 0 2 2 2 0 Penicillin Binding Protein 3 Domain F-box_4 PF15966.5 ORY10892.1 - 0.005 16.7 0.2 0.0077 16.1 0.2 1.4 1 1 0 1 1 1 1 F-box EamA PF00892.20 ORY10893.1 - 2e-20 73.4 26.5 3.1e-10 40.4 4.1 2.2 2 0 0 2 2 2 2 EamA-like transporter family TssN PF17555.2 ORY10893.1 - 1.9 7.8 6.6 0.44 9.9 0.8 2.3 2 0 0 2 2 2 0 Type VI secretion system, TssN PNGaseA PF12222.8 ORY10896.1 - 1.3e-171 571.2 0.3 1.8e-171 570.8 0.3 1.0 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A DUF1279 PF06916.13 ORY10898.1 - 1.8e-22 79.7 0.0 2.4e-22 79.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) HET PF06985.11 ORY10899.1 - 2.1e-35 122.2 0.2 3.8e-35 121.4 0.2 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Tcp11 PF05794.13 ORY10900.1 - 2.1e-103 346.8 1.0 5.5e-103 345.4 0.0 2.1 2 0 0 2 2 2 1 T-complex protein 11 DUF1116 PF06545.11 ORY10900.1 - 0.17 11.3 0.9 0.32 10.4 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1116) UPF0242 PF06785.11 ORY10900.1 - 0.52 10.4 5.3 1.2 9.2 5.3 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus SBE2 PF17076.5 ORY10922.1 - 0.063 11.5 0.1 0.075 11.3 0.1 1.1 1 0 0 1 1 1 0 SBE2, cell-wall formation Mid2 PF04478.12 ORY10923.1 - 0.0089 15.9 0.4 0.024 14.5 0.4 1.7 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Inhibitor_I71 PF12628.7 ORY10923.1 - 0.071 13.0 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Falstatin, cysteine peptidase inhibitor MtrG PF04210.13 ORY10923.1 - 0.2 11.6 0.3 0.34 10.8 0.3 1.3 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit G GSDH PF07995.11 ORY10924.1 - 2.1e-115 385.6 0.1 2.4e-115 385.4 0.1 1.0 1 0 0 1 1 1 1 Glucose / Sorbosone dehydrogenase Reg_prop PF07494.11 ORY10924.1 - 0.025 14.8 1.2 43 4.8 0.0 4.0 3 0 0 3 3 3 0 Two component regulator propeller SPATA48 PF15073.6 ORY10925.1 - 0.0092 16.3 0.9 0.014 15.7 0.9 1.2 1 0 0 1 1 1 1 Spermatogenesis-associated protein 48 hEGF PF12661.7 ORY10925.1 - 0.062 13.9 2.4 0.16 12.7 2.4 1.7 1 0 0 1 1 1 0 Human growth factor-like EGF Amidase PF01425.21 ORY10927.1 - 4e-104 349.1 0.0 5.6e-104 348.6 0.0 1.2 1 0 0 1 1 1 1 Amidase Acetyltransf_9 PF13527.7 ORY10927.1 - 0.1 12.7 0.1 0.86 9.7 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain TMEM18 PF14770.6 ORY10929.1 - 0.056 13.4 1.9 0.1 12.6 1.6 1.6 1 1 0 1 1 1 0 Transmembrane protein 18 5_nucleotid_C PF02872.18 ORY10933.1 - 9.5e-38 129.9 0.2 2.1e-37 128.8 0.2 1.6 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain YmdB PF13277.6 ORY10933.1 - 0.0013 18.2 0.4 0.0027 17.1 0.4 1.5 1 0 0 1 1 1 1 YmdB-like protein BB_PF PF18063.1 ORY10933.1 - 0.058 13.0 0.4 0.14 11.7 0.4 1.6 1 0 0 1 1 1 0 Beta barrel Pore-forming domain BUD22 PF09073.10 ORY10936.1 - 5.9e-86 289.5 23.9 6.9e-86 289.3 23.9 1.0 1 0 0 1 1 1 1 BUD22 AmpE PF17113.5 ORY10936.1 - 0.26 10.6 0.0 0.4 10.0 0.0 1.2 1 0 0 1 1 1 0 Regulatory signalling modulator protein AmpE Sugar_tr PF00083.24 ORY10937.1 - 9.9e-75 252.1 24.8 1.2e-74 251.9 24.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY10937.1 - 1.7e-24 86.5 21.7 1.7e-24 86.5 21.7 2.4 1 1 2 3 3 3 2 Major Facilitator Superfamily MFS_1 PF07690.16 ORY10938.1 - 5.1e-37 127.6 36.1 5.8e-37 127.4 36.1 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Myb_DNA-binding PF00249.31 ORY10938.1 - 0.049 13.8 0.1 0.12 12.6 0.1 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain MNSV_P7B PF06692.11 ORY10938.1 - 0.11 12.5 2.3 0.13 12.3 0.1 2.1 2 0 0 2 2 2 0 Melon necrotic spot virus P7B protein adh_short_C2 PF13561.6 ORY10939.1 - 2.3e-50 171.3 0.0 2.9e-50 171.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY10939.1 - 2.1e-44 151.3 0.1 2.5e-44 151.1 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORY10939.1 - 8.7e-07 29.0 0.1 1.6e-06 28.1 0.1 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 ORY10939.1 - 0.12 11.8 0.1 0.37 10.2 0.1 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Fungal_trans_2 PF11951.8 ORY10940.1 - 1.7e-11 43.6 0.2 3.1e-11 42.7 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY10940.1 - 1.7e-08 34.5 11.3 2.9e-08 33.7 11.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TMEM95 PF15203.6 ORY10940.1 - 0.25 11.0 2.2 0.65 9.6 2.2 1.6 1 0 0 1 1 1 0 TMEM95 family F_bP_aldolase PF01116.20 ORY10941.1 - 5.3e-75 252.5 0.0 6e-75 252.3 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II CobS PF02654.15 ORY10941.1 - 0.11 12.7 0.1 0.15 12.2 0.1 1.3 1 0 0 1 1 1 0 Cobalamin-5-phosphate synthase SMP_2 PF10144.9 ORY10941.1 - 0.11 12.1 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial virulence factor haemolysin Glyco_hydro_26 PF02156.15 ORY10942.1 - 8.5e-10 38.5 0.1 1.3e-09 38.0 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 26 Cellulase PF00150.18 ORY10942.1 - 0.017 14.5 0.3 0.41 10.0 0.1 2.1 1 1 1 2 2 2 0 Cellulase (glycosyl hydrolase family 5) Meckelin PF09773.9 ORY10943.1 - 0.72 7.9 3.4 1.2 7.1 3.4 1.3 1 0 0 1 1 1 0 Meckelin (Transmembrane protein 67) Carboxyl_trans PF01039.22 ORY10944.1 - 4e-78 263.2 0.0 5e-78 262.9 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 ORY10945.1 - 5.9e-57 192.6 0.0 9e-57 192.0 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.19 ORY10945.1 - 1.3e-30 105.7 0.0 3.3e-30 104.4 0.0 1.7 2 0 0 2 2 1 1 Biotin carboxylase C-terminal domain Biotin_carb_N PF00289.22 ORY10945.1 - 2.8e-27 95.4 0.0 6.4e-27 94.3 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_lipoyl PF00364.22 ORY10945.1 - 4.5e-13 48.8 1.8 1.6e-12 47.1 1.9 2.0 2 0 0 2 2 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 ORY10945.1 - 2.8e-07 30.3 0.0 4.9e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 ORY10945.1 - 3e-06 26.9 0.1 9.6e-06 25.3 0.0 1.8 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_3 PF02655.14 ORY10945.1 - 1.6e-05 25.0 0.0 2.9e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 ORY10945.1 - 0.00018 21.3 0.0 0.00042 20.1 0.0 1.6 1 0 0 1 1 1 1 Biotin-lipoyl like DUF2118 PF09891.9 ORY10945.1 - 0.0026 17.7 0.5 0.005 16.8 0.5 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2118) RimK PF08443.11 ORY10945.1 - 0.014 15.0 0.0 0.043 13.4 0.0 1.8 1 1 0 1 1 1 0 RimK-like ATP-grasp domain RnfC_N PF13375.6 ORY10945.1 - 0.027 14.4 0.2 0.068 13.1 0.2 1.6 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain EF-hand_13 PF17958.1 ORY10945.1 - 0.1 12.4 0.0 0.35 10.7 0.0 2.0 1 0 0 1 1 1 0 EF-hand domain EutQ PF06249.12 ORY10946.1 - 0.14 11.9 1.1 0.22 11.3 1.1 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutQ Transket_pyr PF02779.24 ORY10948.1 - 3.6e-46 157.1 0.0 5.5e-46 156.5 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 ORY10948.1 - 5e-35 120.1 0.3 4e-34 117.2 0.2 2.1 2 0 0 2 2 2 1 Transketolase, C-terminal domain PFOR_II PF17147.4 ORY10948.1 - 0.00039 20.7 0.0 0.0013 19.0 0.0 1.8 2 0 0 2 2 2 1 Pyruvate:ferredoxin oxidoreductase core domain II DUF21 PF01595.20 ORY10949.1 - 6.6e-34 117.1 0.0 1.1e-33 116.4 0.0 1.3 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 ORY10949.1 - 2.4e-06 27.9 0.6 0.044 14.2 0.0 3.3 3 0 0 3 3 3 2 CBS domain CCD PF07860.11 ORY10949.1 - 0.049 13.7 0.0 0.14 12.2 0.0 1.7 1 0 0 1 1 1 0 WisP family C-Terminal Region UPF0239 PF06783.11 ORY10949.1 - 8.3 6.7 6.2 68 3.7 4.3 2.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0239) DUF3328 PF11807.8 ORY10950.1 - 5 6.8 9.4 6.2 6.5 0.8 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF3328) TGase_elicitor PF16683.5 ORY10954.1 - 0.11 11.3 0.0 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 Transglutaminase elicitor zf-Sec23_Sec24 PF04810.15 ORY10955.1 - 4.2 7.5 6.3 0.65 10.1 1.3 2.4 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger Hydrolase_4 PF12146.8 ORY10956.1 - 5.4e-13 48.8 0.0 8.5e-13 48.1 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ORY10956.1 - 1.4e-09 37.9 0.0 2.1e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORY10956.1 - 8.4e-08 33.1 0.0 1.2e-07 32.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family LIDHydrolase PF10230.9 ORY10956.1 - 2.4e-06 27.3 0.0 4.1e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Peptidase_S9 PF00326.21 ORY10956.1 - 3.9e-05 23.2 0.1 6e-05 22.6 0.1 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family PGAP1 PF07819.13 ORY10956.1 - 8.2e-05 22.4 0.0 0.00014 21.6 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein LIP PF03583.14 ORY10956.1 - 0.0032 16.8 0.2 0.0048 16.3 0.2 1.2 1 0 0 1 1 1 1 Secretory lipase Peptidase_S15 PF02129.18 ORY10956.1 - 0.013 15.1 0.0 0.017 14.8 0.0 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Ser_hydrolase PF06821.13 ORY10956.1 - 0.016 15.1 0.0 0.029 14.2 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase DUF676 PF05057.14 ORY10956.1 - 0.02 14.4 0.1 0.03 13.9 0.1 1.4 1 1 0 1 1 1 0 Putative serine esterase (DUF676) DUF1749 PF08538.10 ORY10956.1 - 0.064 12.3 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Abhydrolase_8 PF06259.12 ORY10956.1 - 0.088 12.4 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase DUF2201_N PF13203.6 ORY10959.1 - 9.3 5.8 12.1 0.026 14.1 1.2 2.2 3 0 0 3 3 3 0 Putative metallopeptidase domain Isochorismatase PF00857.20 ORY10960.1 - 8.1e-37 127.1 0.0 9.2e-37 126.9 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family Abhydrolase_3 PF07859.13 ORY10962.1 - 1.1e-15 58.0 0.0 3.4e-13 49.9 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Gly_transf_sug PF04488.15 ORY10963.1 - 4.6e-08 33.6 0.0 9.6e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 ORY10963.1 - 0.14 11.5 0.3 0.24 10.6 0.3 1.3 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain Caps_synth PF05704.12 ORY10963.1 - 0.22 10.9 0.0 0.33 10.3 0.0 1.2 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein HTH_23 PF13384.6 ORY10964.1 - 1.6e-06 27.7 0.0 0.015 15.1 0.0 2.2 2 0 0 2 2 2 2 Homeodomain-like domain Sigma70_r4 PF04545.16 ORY10964.1 - 2.3e-05 23.8 0.0 0.012 15.1 0.0 2.2 2 0 0 2 2 2 2 Sigma-70, region 4 HTH_24 PF13412.6 ORY10964.1 - 0.00019 20.9 0.1 0.62 9.7 0.0 2.4 2 0 0 2 2 2 2 Winged helix-turn-helix DNA-binding Sigma70_r4_2 PF08281.12 ORY10964.1 - 0.0013 18.4 0.5 0.0057 16.3 0.1 2.0 2 0 0 2 2 2 1 Sigma-70, region 4 GerE PF00196.19 ORY10964.1 - 0.0013 18.2 0.3 0.042 13.4 0.1 2.2 2 0 0 2 2 2 1 Bacterial regulatory proteins, luxR family TrmB PF01978.19 ORY10964.1 - 0.027 14.4 0.0 2.5 8.1 0.0 2.2 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB HTH_28 PF13518.6 ORY10964.1 - 0.07 13.3 0.1 0.34 11.1 0.1 2.2 2 1 0 2 2 2 0 Helix-turn-helix domain HTH_Tnp_4 PF13613.6 ORY10964.1 - 0.1 12.4 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease MarR_2 PF12802.7 ORY10964.1 - 0.13 12.1 0.1 0.87 9.5 0.0 2.0 2 0 0 2 2 2 0 MarR family HTH_32 PF13565.6 ORY10964.1 - 0.17 12.5 0.4 3.7 8.2 0.2 2.4 1 1 1 2 2 2 0 Homeodomain-like domain VHS PF00790.19 ORY10965.1 - 8.4e-36 122.9 0.0 8.4e-36 122.9 0.0 2.0 2 0 0 2 2 2 1 VHS domain FYVE PF01363.21 ORY10965.1 - 2.8e-17 62.6 3.9 4.9e-17 61.8 3.9 1.4 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.20 ORY10965.1 - 8.4e-06 25.4 7.6 0.0026 17.5 2.1 2.6 2 0 0 2 2 2 2 Ubiquitin interaction motif GAT PF03127.14 ORY10965.1 - 5e-05 23.5 0.1 0.00017 21.9 0.0 2.0 2 0 0 2 2 2 1 GAT domain FYVE_2 PF02318.16 ORY10965.1 - 0.0033 17.6 1.4 0.0069 16.6 1.4 1.4 1 0 0 1 1 1 1 FYVE-type zinc finger OAD_gamma PF04277.13 ORY10965.1 - 0.0053 17.3 1.0 0.0053 17.3 1.0 3.4 2 1 0 2 2 2 1 Oxaloacetate decarboxylase, gamma chain Npa1 PF11707.8 ORY10965.1 - 0.058 12.7 0.0 0.091 12.1 0.0 1.2 1 0 0 1 1 1 0 Ribosome 60S biogenesis N-terminal UCH PF00443.29 ORY10966.1 - 2.2e-54 184.7 0.0 3.1e-54 184.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 ORY10966.1 - 2.8e-17 63.3 0.0 1.2e-16 61.2 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.20 ORY10966.1 - 5e-05 23.8 0.0 0.00011 22.7 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain Rubredoxin PF00301.20 ORY10966.1 - 0.13 12.3 0.3 2.4 8.3 0.4 2.5 2 0 0 2 2 2 0 Rubredoxin WD40 PF00400.32 ORY10967.1 - 3.6e-75 246.0 43.0 3.9e-10 40.2 1.1 8.0 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY10967.1 - 1.4e-30 105.4 6.9 0.0046 17.2 0.0 7.6 1 1 6 7 7 7 7 Anaphase-promoting complex subunit 4 WD40 domain NACHT PF05729.12 ORY10967.1 - 1.3e-22 80.5 0.1 3.3e-22 79.2 0.1 1.7 1 0 0 1 1 1 1 NACHT domain Ge1_WD40 PF16529.5 ORY10967.1 - 5.7e-15 55.1 17.2 0.34 9.8 0.1 7.2 1 1 6 7 7 7 7 WD40 region of Ge1, enhancer of mRNA-decapping protein HET PF06985.11 ORY10967.1 - 2e-14 54.2 4.4 5.3e-12 46.3 4.4 2.9 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Nup160 PF11715.8 ORY10967.1 - 1.7e-10 40.2 17.0 0.29 9.7 0.1 7.1 1 1 6 7 7 7 7 Nucleoporin Nup120/160 Nbas_N PF15492.6 ORY10967.1 - 4.9e-07 29.3 24.9 0.64 9.3 0.3 7.3 1 1 6 7 7 7 6 Neuroblastoma-amplified sequence, N terminal RNA_helicase PF00910.22 ORY10967.1 - 0.016 15.6 0.0 0.055 13.9 0.0 1.9 1 0 0 1 1 1 0 RNA helicase DUF4097 PF13349.6 ORY10967.1 - 1.4 8.2 5.1 3.3 7.0 2.3 2.3 1 1 1 2 2 2 0 Putative adhesin Baculo_gp64 PF03273.13 ORY10967.1 - 8.3 5.1 16.6 5.9 5.6 0.4 4.1 2 1 3 5 5 5 0 Baculovirus gp64 envelope glycoprotein family Arginosuc_synth PF00764.19 ORY10968.1 - 3.9e-151 503.8 0.0 4.5e-151 503.6 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 ORY10968.1 - 0.062 12.8 0.0 0.097 12.2 0.0 1.3 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC DUF4188 PF13826.6 ORY10973.1 - 2.8e-22 79.2 0.0 3.9e-22 78.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4188) Abhydrolase_3 PF07859.13 ORY10974.1 - 2.8e-26 92.7 0.0 3.8e-26 92.3 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 ORY10974.1 - 2.1e-14 53.2 0.0 3.1e-14 52.6 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase COesterase PF00135.28 ORY10974.1 - 0.0028 16.6 0.1 0.0094 14.9 0.1 1.7 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 ORY10974.1 - 0.098 12.1 0.0 0.37 10.2 0.0 1.9 2 0 0 2 2 2 0 Prolyl oligopeptidase family PAE PF03283.13 ORY10974.1 - 0.17 11.0 0.0 0.31 10.1 0.0 1.3 1 0 0 1 1 1 0 Pectinacetylesterase Dynamin_M PF01031.20 ORY10975.1 - 1.7e-24 86.6 0.1 1.2e-19 70.7 0.0 2.4 2 0 0 2 2 2 2 Dynamin central region Dynamin_N PF00350.23 ORY10975.1 - 4.5e-16 59.4 0.0 2.5e-15 57.0 0.0 2.2 2 0 0 2 2 2 1 Dynamin family GED PF02212.18 ORY10975.1 - 1e-06 28.8 0.2 2.6e-06 27.5 0.2 1.7 1 0 0 1 1 1 1 Dynamin GTPase effector domain UBA2_C PF16195.5 ORY10975.1 - 0.015 15.9 0.8 0.062 14.0 0.8 2.0 1 0 0 1 1 1 0 SUMO-activating enzyme subunit 2 C-terminus MMR_HSR1 PF01926.23 ORY10975.1 - 0.058 13.5 0.0 0.26 11.4 0.0 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_15 PF13175.6 ORY10975.1 - 0.61 9.7 5.5 6.4 6.4 0.0 2.6 3 0 0 3 3 3 0 AAA ATPase domain Peptidase_S30 PF01577.16 ORY10975.1 - 2.3 7.8 4.7 0.43 10.2 0.1 2.0 2 0 0 2 2 2 0 Potyvirus P1 protease AAA_23 PF13476.6 ORY10975.1 - 2.8 8.4 5.7 30 5.0 0.0 2.9 3 0 0 3 3 3 0 AAA domain Flavokinase PF01687.17 ORY10976.1 - 1.8e-31 108.7 0.0 2.5e-31 108.3 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase Aldo_ket_red PF00248.21 ORY10977.1 - 5.4e-18 65.2 0.0 6.9e-18 64.9 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family APC_N_CC PF16689.5 ORY10979.1 - 0.05 13.7 2.0 0.23 11.6 0.2 2.1 2 0 0 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain Pes-10 PF07149.11 ORY10979.1 - 0.49 9.4 4.1 0.55 9.2 4.1 1.0 1 0 0 1 1 1 0 Pes-10 Afi1 PF07792.12 ORY10979.1 - 0.49 10.9 3.9 0.58 10.6 3.9 1.1 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Phage_1_1 PF08200.11 ORY10979.1 - 1 9.8 6.8 0.36 11.3 1.7 2.1 2 0 0 2 2 2 0 Bacteriophage 1.1 Protein MARVEL PF01284.23 ORY10982.1 - 0.00032 20.8 7.0 0.0011 19.1 6.8 1.9 1 1 0 1 1 1 1 Membrane-associating domain Saf_2TM PF18303.1 ORY10982.1 - 1 9.0 3.0 18 4.9 0.0 2.2 2 0 0 2 2 2 0 SAVED-fused 2TM effector domain CHAT PF12770.7 ORY10983.1 - 1.2e-31 110.2 0.2 2.1e-31 109.4 0.2 1.4 1 0 0 1 1 1 1 CHAT domain TPR_10 PF13374.6 ORY10983.1 - 0.13 12.1 11.6 8.1 6.5 0.6 5.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.17 ORY10983.1 - 0.93 9.8 2.6 12 6.3 0.0 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat GpcrRhopsn4 PF10192.9 ORY10985.1 - 0.0091 15.4 0.2 0.023 14.1 0.2 1.7 1 0 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain Cutinase PF01083.22 ORY10986.1 - 2.4e-11 43.9 0.7 6.7e-09 36.0 0.7 2.7 1 1 0 1 1 1 1 Cutinase DUF732 PF05305.14 ORY10986.1 - 0.095 13.1 0.0 0.29 11.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF732) Nrf1_DNA-bind PF10491.9 ORY10986.1 - 0.11 12.2 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 NLS-binding and DNA-binding and dimerisation domains of Nrf1 DUF1996 PF09362.10 ORY10987.1 - 6.2e-38 131.1 6.9 2.1e-35 122.8 0.2 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF1996) Ank_2 PF12796.7 ORY10990.1 - 1.3e-12 48.2 0.0 4.4e-12 46.4 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ORY10990.1 - 3.9e-11 42.2 0.1 0.0003 21.0 0.0 4.0 3 1 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 ORY10990.1 - 2.1e-10 40.6 1.7 0.0022 18.4 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 ORY10990.1 - 2.1e-10 40.9 0.1 0.00096 19.7 0.0 3.3 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 ORY10990.1 - 2.2e-08 34.2 0.3 0.00097 19.4 0.1 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Trypsin PF00089.26 ORY11011.1 - 4.4e-09 36.5 0.0 6.6e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 ORY11011.1 - 1.4e-05 26.1 0.0 2.3e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain NUDIX_4 PF14815.6 ORY11012.1 - 1.1e-19 70.4 0.0 8e-19 67.7 0.0 2.3 2 0 0 2 2 2 1 NUDIX domain HhH-GPD PF00730.25 ORY11012.1 - 2.1e-14 53.8 0.0 4.4e-14 52.8 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 ORY11012.1 - 0.013 15.4 0.6 0.059 13.3 0.1 2.4 3 0 0 3 3 3 0 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.9 ORY11012.1 - 0.1 13.0 4.9 0.35 11.3 4.9 2.0 1 1 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III Whib PF02467.16 ORY11012.1 - 1.3 9.7 3.7 1 10.0 0.8 2.3 2 0 0 2 2 2 0 Transcription factor WhiB PH PF00169.29 ORY11013.1 - 0.02 15.4 0.0 0.041 14.4 0.0 1.6 1 0 0 1 1 1 0 PH domain Cnn_1N PF07989.11 ORY11014.1 - 0.0047 17.1 0.7 0.015 15.4 0.0 2.0 2 0 0 2 2 2 1 Centrosomin N-terminal motif 1 Pox_A_type_inc PF04508.12 ORY11014.1 - 0.04 13.8 3.8 0.13 12.1 3.8 2.0 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat DivIC PF04977.15 ORY11014.1 - 0.045 13.5 1.8 0.89 9.4 0.1 2.2 2 0 0 2 2 2 0 Septum formation initiator SlyX PF04102.12 ORY11014.1 - 0.062 13.9 5.4 3.7 8.2 1.3 2.4 2 0 0 2 2 2 0 SlyX Shugoshin_N PF07558.11 ORY11014.1 - 0.079 12.8 2.9 0.081 12.8 1.4 1.8 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region DUF2968 PF11180.8 ORY11014.1 - 0.54 9.9 4.7 1.6 8.3 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) Sec62 PF03839.16 ORY11015.1 - 3e-74 249.2 1.8 1.6e-73 246.8 0.1 2.0 2 0 0 2 2 2 1 Translocation protein Sec62 DUF4337 PF14235.6 ORY11015.1 - 0.035 14.2 0.4 0.035 14.2 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) SPC12 PF06645.13 ORY11015.1 - 3.4 7.8 6.9 0.34 11.0 2.0 1.8 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) TFIIA PF03153.13 ORY11015.1 - 4.8 7.1 14.3 0.2 11.6 9.2 1.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit IF2_assoc PF08364.11 ORY11016.1 - 0.92 9.8 3.5 3.9 7.8 0.1 2.4 2 0 0 2 2 2 0 Bacterial translation initiation factor IF-2 associated region DUF3439 PF11921.8 ORY11017.1 - 0.093 12.7 1.5 0.16 11.9 1.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Glyco_transf_41 PF13844.6 ORY11018.1 - 5.7e-108 361.3 0.1 1.2e-55 188.8 0.0 3.1 1 1 1 2 2 2 2 Glycosyl transferase family 41 TPR_1 PF00515.28 ORY11018.1 - 3.7e-13 48.7 10.4 0.0015 18.3 0.0 5.1 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 ORY11018.1 - 2.5e-11 42.8 16.8 0.0032 17.4 0.1 5.6 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_12 PF13424.6 ORY11018.1 - 1.1e-10 41.7 6.9 5.9e-05 23.3 0.6 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 ORY11018.1 - 7.7e-10 38.8 5.3 0.02 15.7 0.1 5.1 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 ORY11018.1 - 9.3e-09 34.8 10.4 0.0018 18.3 0.0 5.0 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 ORY11018.1 - 1.3e-08 34.4 13.2 0.0016 18.0 0.2 5.2 3 1 2 5 5 5 3 TPR repeat TPR_10 PF13374.6 ORY11018.1 - 1.5e-08 34.3 12.5 0.061 13.2 0.1 6.3 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 ORY11018.1 - 5.3e-07 30.1 14.7 0.00032 21.1 0.6 3.8 3 1 2 5 5 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 ORY11018.1 - 5.4e-07 29.2 3.8 0.066 13.3 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 ORY11018.1 - 1.2e-06 28.5 10.7 2 9.0 0.3 5.7 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.6 ORY11018.1 - 4.4e-05 24.0 11.8 0.27 11.9 0.3 4.2 2 2 1 4 4 4 3 Tetratricopeptide repeat BTAD PF03704.17 ORY11018.1 - 0.00066 20.1 1.1 0.94 9.9 0.0 2.8 2 0 0 2 2 2 2 Bacterial transcriptional activator domain ANAPC3 PF12895.7 ORY11018.1 - 0.0024 18.1 0.7 0.035 14.3 0.4 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 ORY11018.1 - 0.077 13.2 2.4 0.19 11.9 0.2 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Herpes_DNAp_acc PF04929.12 ORY11018.1 - 1.4 7.8 4.2 3 6.7 4.2 1.4 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Myb_DNA-binding PF00249.31 ORY11022.1 - 3.5e-25 87.9 3.4 2.6e-13 50.0 0.4 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORY11022.1 - 5.1e-16 58.7 3.2 1.1e-12 48.1 0.1 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 ORY11022.1 - 0.006 16.6 0.0 0.011 15.8 0.0 1.4 1 0 0 1 1 1 1 SLIDE DUF2774 PF11242.8 ORY11022.1 - 0.029 14.5 0.0 0.07 13.3 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2774) HTH_23 PF13384.6 ORY11022.1 - 0.043 13.6 0.2 0.079 12.8 0.2 1.4 1 0 0 1 1 1 0 Homeodomain-like domain Sigma70_r4_2 PF08281.12 ORY11022.1 - 0.084 12.6 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_38 PF13936.6 ORY11022.1 - 0.1 12.4 0.1 0.2 11.5 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Lectin_C PF00059.21 ORY11024.1 - 0.11 13.3 0.0 0.23 12.2 0.0 1.5 1 0 0 1 1 1 0 Lectin C-type domain TMEM154 PF15102.6 ORY11024.1 - 0.74 9.7 0.0 0.74 9.7 0.0 2.3 3 0 0 3 3 3 0 TMEM154 protein family PLDc_2 PF13091.6 ORY11025.1 - 2.6e-16 59.7 0.0 5.9e-06 26.2 0.0 3.5 3 0 0 3 3 3 3 PLD-like domain PLDc PF00614.22 ORY11025.1 - 1.9e-15 56.3 2.5 1.8e-08 34.2 0.2 2.8 2 0 0 2 2 2 2 Phospholipase D Active site motif adh_short PF00106.25 ORY11026.1 - 1.5e-20 73.5 0.1 1.7e-20 73.4 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY11026.1 - 8.8e-14 51.6 0.2 9.8e-14 51.5 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY11026.1 - 1.7e-06 28.0 0.0 2.3e-06 27.6 0.0 1.0 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ORY11026.1 - 1.4e-05 24.7 0.1 1.6e-05 24.5 0.1 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 ORY11026.1 - 4.1e-05 23.6 0.2 4.5e-05 23.4 0.2 1.1 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 ORY11026.1 - 0.0016 17.6 0.0 0.0018 17.4 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 ORY11026.1 - 0.0028 17.1 0.1 0.0033 16.9 0.1 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Lipase_bact_N PF12262.8 ORY11026.1 - 0.028 13.8 0.2 0.033 13.5 0.2 1.1 1 0 0 1 1 1 0 Bacterial virulence factor lipase N-terminal NmrA PF05368.13 ORY11026.1 - 0.03 13.9 0.4 0.032 13.8 0.4 1.1 1 0 0 1 1 1 0 NmrA-like family Glyco_hydro_43 PF04616.14 ORY11027.1 - 8.8e-25 87.6 0.4 1e-24 87.4 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 MCM PF00493.23 ORY11028.1 - 1e-96 322.4 0.2 1.8e-96 321.5 0.2 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 ORY11028.1 - 9.2e-32 109.5 0.1 1.7e-31 108.7 0.1 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 ORY11028.1 - 3.4e-23 81.9 0.9 8.3e-23 80.6 0.9 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 ORY11028.1 - 9.6e-13 48.6 0.0 2.7e-12 47.2 0.0 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 ORY11028.1 - 1.5e-07 31.0 0.0 1.9e-06 27.4 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 ORY11028.1 - 0.0048 16.8 0.0 0.012 15.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 ORY11028.1 - 0.014 15.1 0.0 0.035 13.8 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain DNA_mis_repair PF01119.19 ORY11029.1 - 1.2e-19 70.1 0.0 2.4e-18 65.9 0.0 2.7 3 0 0 3 3 3 1 DNA mismatch repair protein, C-terminal domain MutL_C PF08676.11 ORY11029.1 - 3.3e-19 69.1 0.0 2.1e-18 66.5 0.0 2.1 1 1 0 1 1 1 1 MutL C terminal dimerisation domain HATPase_c_3 PF13589.6 ORY11029.1 - 5.3e-11 42.5 0.0 1.4e-10 41.1 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 ORY11029.1 - 6.8e-07 29.8 0.0 1.8e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase adh_short PF00106.25 ORY11030.1 - 3.5e-32 111.4 0.0 5.8e-32 110.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY11030.1 - 7.3e-25 87.9 0.0 1.1e-24 87.3 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY11030.1 - 2.9e-05 24.0 0.4 0.00046 20.2 0.4 2.2 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 ORY11030.1 - 0.0012 18.4 0.0 0.0021 17.5 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family ADH_zinc_N PF00107.26 ORY11030.1 - 0.058 13.4 0.3 0.24 11.4 0.1 2.1 2 1 0 2 2 2 0 Zinc-binding dehydrogenase Eno-Rase_NADH_b PF12242.8 ORY11030.1 - 0.15 11.8 0.2 1.2 9.0 0.2 2.1 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase LSM PF01423.22 ORY11031.1 - 7.8e-16 57.5 0.0 1.1e-15 57.0 0.0 1.3 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 ORY11031.1 - 0.0021 18.1 0.0 0.0027 17.8 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain API5 PF05918.11 ORY11031.1 - 2.7 6.7 4.8 3.1 6.5 4.8 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) AAA_13 PF13166.6 ORY11032.1 - 0.0092 14.7 1.5 0.0092 14.7 1.5 1.4 2 0 0 2 2 2 1 AAA domain IFT57 PF10498.9 ORY11032.1 - 0.013 14.5 1.6 0.013 14.5 1.6 2.1 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 TMEM52 PF14979.6 ORY11032.1 - 0.053 13.4 5.6 0.32 10.9 0.5 2.6 2 0 0 2 2 2 0 Transmembrane 52 DUF2325 PF10087.9 ORY11032.1 - 0.11 12.6 1.4 0.25 11.5 0.5 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2325) DUF2970 PF11174.8 ORY11032.1 - 0.16 11.8 0.3 0.33 10.8 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2970) CENP-K PF11802.8 ORY11032.1 - 0.19 11.2 10.0 0.61 9.6 5.9 2.2 2 0 0 2 2 2 0 Centromere-associated protein K ADIP PF11559.8 ORY11032.1 - 0.28 11.3 10.5 0.058 13.5 3.4 2.3 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding MPS2 PF17060.5 ORY11032.1 - 0.29 10.3 2.8 0.21 10.8 0.3 1.8 2 0 0 2 2 2 0 Monopolar spindle protein 2 AAA_23 PF13476.6 ORY11032.1 - 0.32 11.5 7.2 0.13 12.8 1.1 2.2 2 0 0 2 2 2 0 AAA domain DUF5082 PF16888.5 ORY11032.1 - 0.4 11.0 11.3 1.1 9.5 2.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) Calc_CGRP_IAPP PF00214.19 ORY11032.1 - 0.59 10.5 0.0 0.59 10.5 0.0 2.6 2 1 0 2 2 2 0 Calcitonin / CGRP / IAPP family DUF641 PF04859.12 ORY11032.1 - 0.72 10.2 5.7 0.28 11.5 0.9 2.2 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) V_ATPase_I PF01496.19 ORY11032.1 - 1.1 7.0 3.8 0.33 8.8 0.7 1.6 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family HAUS6_N PF14661.6 ORY11032.1 - 4 7.0 9.0 6.6 6.2 2.3 2.2 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus DUF3584 PF12128.8 ORY11032.1 - 4.5 4.7 10.9 0.1 10.1 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) DUF4407 PF14362.6 ORY11032.1 - 6.3 6.1 5.9 4.2 6.7 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Phage_Mu_Gam PF07352.12 ORY11032.1 - 6.4 6.7 14.2 0.96 9.3 7.6 2.2 2 0 0 2 2 2 0 Bacteriophage Mu Gam like protein S4 PF01479.25 ORY11033.1 - 1.9e-16 59.5 0.2 7.5e-16 57.6 0.0 2.0 2 0 0 2 2 2 1 S4 domain DUF4404 PF14357.6 ORY11033.1 - 0.008 16.8 0.7 0.008 16.8 0.7 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF4404) PrkA PF06798.12 ORY11033.1 - 0.021 14.4 0.3 0.039 13.6 0.3 1.3 1 0 0 1 1 1 0 PrkA serine protein kinase C-terminal domain DUF4710 PF15828.5 ORY11033.1 - 0.077 13.1 0.2 0.25 11.5 0.2 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4710) S4_2 PF13275.6 ORY11033.1 - 0.16 11.8 0.0 0.29 11.0 0.0 1.3 1 0 0 1 1 1 0 S4 domain DUF3597 PF12200.8 ORY11033.1 - 0.22 12.0 3.4 0.34 11.5 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3597) La PF05383.17 ORY11034.1 - 3.6e-17 62.1 0.1 6.9e-17 61.3 0.1 1.5 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 ORY11034.1 - 4.2e-05 23.3 0.2 9.8e-05 22.1 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cyclin_N PF00134.23 ORY11036.1 - 8.6e-11 41.7 0.1 2.9e-08 33.5 0.0 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain p450 PF00067.22 ORY11037.1 - 2.5e-50 171.6 0.0 3.4e-50 171.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PWI PF01480.17 ORY11038.1 - 2.2e-06 27.9 0.8 4.5e-06 26.9 0.0 1.9 2 0 0 2 2 2 1 PWI domain Nup35_RRM_2 PF14605.6 ORY11038.1 - 0.00012 22.0 0.3 0.00024 21.1 0.3 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_1 PF00076.22 ORY11038.1 - 0.00092 19.0 0.8 0.002 17.9 0.3 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 ORY11038.1 - 0.0021 18.1 2.2 0.005 16.8 2.2 1.7 1 0 0 1 1 1 1 Zinc finger domain Sec34 PF04136.15 ORY11038.1 - 0.034 14.0 4.4 0.061 13.2 4.4 1.3 1 0 0 1 1 1 0 Sec34-like family PG_binding_2 PF08823.11 ORY11038.1 - 0.089 13.1 1.6 0.2 12.0 0.1 2.4 2 0 0 2 2 2 0 Putative peptidoglycan binding domain RRM_5 PF13893.6 ORY11038.1 - 0.1 12.2 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 ORY11038.1 - 0.11 12.5 7.6 69 3.6 7.6 2.9 1 1 0 1 1 1 0 RNA binding motif zf-CCCH PF00642.24 ORY11038.1 - 0.16 11.9 2.7 0.31 11.0 2.7 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) MCU PF04678.13 ORY11038.1 - 0.29 11.2 5.7 0.62 10.1 5.7 1.5 1 0 0 1 1 1 0 Mitochondrial calcium uniporter Golgin_A5 PF09787.9 ORY11038.1 - 0.39 10.1 13.2 0.63 9.4 13.2 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 TMPIT PF07851.13 ORY11038.1 - 3.7 6.7 6.9 5.4 6.2 6.9 1.1 1 0 0 1 1 1 0 TMPIT-like protein GTP_EFTU PF00009.27 ORY11039.1 - 1.1e-66 224.1 0.1 1.7e-66 223.5 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 ORY11039.1 - 1.3e-34 118.5 0.0 3.8e-34 117.0 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 ORY11039.1 - 8.8e-21 73.7 0.0 2.4e-20 72.4 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 ORY11039.1 - 3.4e-13 49.8 0.0 1.3e-12 47.9 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 ORY11039.1 - 1.3e-11 44.4 0.0 3.2e-11 43.2 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 ORY11039.1 - 0.00017 21.7 0.1 0.00042 20.4 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase MFS_1 PF07690.16 ORY11040.1 - 1.2e-24 86.9 73.1 5.2e-21 75.0 45.5 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 ORY11041.1 - 1.4e-31 109.7 29.3 1.9e-31 109.3 29.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MASE2 PF05230.11 ORY11041.1 - 0.15 12.2 3.9 1.9 8.6 1.0 2.7 2 0 0 2 2 2 0 MASE2 domain ADH_zinc_N PF00107.26 ORY11042.1 - 6.9e-21 74.6 0.9 1.1e-20 74.0 0.9 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ORY11042.1 - 7.5e-07 30.3 0.0 1.7e-06 29.1 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ORY11042.1 - 0.0034 17.3 0.0 0.0062 16.4 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 ORY11042.1 - 0.037 13.5 0.5 0.076 12.5 0.5 1.6 1 0 0 1 1 1 0 short chain dehydrogenase ACP_syn_III_C PF08541.10 ORY11042.1 - 0.057 13.6 0.3 0.16 12.2 0.2 1.9 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal HET PF06985.11 ORY11043.1 - 2.9e-27 95.8 0.1 7e-27 94.6 0.0 1.7 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Glyco_hydro_7 PF00840.20 ORY11044.1 - 1.5e-140 468.8 9.1 1.9e-140 468.5 9.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Fringe PF02434.16 ORY11045.1 - 1.4e-07 31.3 0.0 3.5e-06 26.6 0.0 2.2 1 1 0 1 1 1 1 Fringe-like DUF604 PF04646.12 ORY11045.1 - 0.013 14.9 0.0 0.029 13.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF604 PAN_4 PF14295.6 ORY11045.1 - 0.021 14.7 5.7 0.025 14.5 1.5 2.4 2 0 0 2 2 2 0 PAN domain PAN_3 PF08277.12 ORY11045.1 - 0.29 11.0 7.2 0.28 11.0 2.2 2.4 1 1 1 2 2 2 0 PAN-like domain PAN_2 PF08276.11 ORY11045.1 - 6 7.1 10.0 0.3 11.2 2.8 2.2 2 0 0 2 2 2 0 PAN-like domain Rax2 PF12768.7 ORY11046.1 - 0.00031 20.3 0.3 0.00042 19.8 0.3 1.2 1 0 0 1 1 1 1 Cortical protein marker for cell polarity LysM PF01476.20 ORY11047.1 - 5.6e-13 48.7 1.5 0.0047 17.0 0.0 6.7 7 0 0 7 7 7 4 LysM domain HTH_Tnp_1 PF01527.20 ORY11047.1 - 0.00042 20.6 0.0 5.1 7.5 0.0 3.3 3 0 0 3 3 3 2 Transposase HTH_28 PF13518.6 ORY11047.1 - 0.0074 16.4 0.0 0.93 9.7 0.0 3.2 3 0 0 3 3 3 1 Helix-turn-helix domain Glyco_hydro_18 PF00704.28 ORY11048.1 - 4.3e-71 240.2 1.9 6.3e-71 239.7 1.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 ORY11048.1 - 0.00043 20.7 4.1 0.00043 20.7 4.1 5.5 6 0 0 6 6 6 3 Chitin recognition protein DNase_NucA_NucB PF14040.6 ORY11048.1 - 0.036 14.4 3.2 0.039 14.3 0.0 2.7 3 0 0 3 3 3 0 Deoxyribonuclease NucA/NucB AAA PF00004.29 ORY11050.1 - 8.4e-12 45.7 0.0 2e-11 44.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 ORY11050.1 - 6.6e-06 26.2 0.0 5.4e-05 23.2 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_5 PF07728.14 ORY11050.1 - 7.6e-06 26.0 0.0 2e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 ORY11050.1 - 3.4e-05 23.6 0.0 6.9e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 ORY11050.1 - 3.9e-05 23.9 0.0 9.7e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 ORY11050.1 - 0.0016 18.6 0.4 0.0076 16.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 ORY11050.1 - 0.0027 18.1 0.1 0.018 15.5 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain NTPase_1 PF03266.15 ORY11050.1 - 0.013 15.4 0.4 0.042 13.8 0.1 2.1 2 0 0 2 2 2 0 NTPase AAA_30 PF13604.6 ORY11050.1 - 0.018 14.8 0.7 0.12 12.0 0.2 2.4 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 ORY11050.1 - 0.019 15.5 0.2 0.15 12.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 ORY11050.1 - 0.029 14.4 0.0 0.059 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 ORY11050.1 - 0.044 13.7 0.5 0.1 12.5 0.0 1.8 2 0 0 2 2 2 0 RsgA GTPase TsaE PF02367.17 ORY11050.1 - 0.069 13.1 0.0 0.26 11.3 0.0 1.9 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_19 PF13245.6 ORY11050.1 - 0.071 13.5 0.1 0.31 11.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 ORY11050.1 - 0.14 12.7 0.6 0.56 10.7 0.1 2.3 2 0 0 2 2 2 0 ABC transporter Fungal_trans PF04082.18 ORY11051.1 - 2.7e-30 105.3 0.0 4e-30 104.7 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY11051.1 - 1.5e-08 34.6 9.0 3e-08 33.6 9.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Amidohydro_2 PF04909.14 ORY11052.1 - 9.4e-15 55.2 0.1 9.5e-14 51.9 0.0 2.0 2 0 0 2 2 2 1 Amidohydrolase Sortilin-Vps10 PF15902.5 ORY11053.1 - 0.031 13.1 0.1 0.17 10.6 0.4 2.0 2 1 0 2 2 2 0 Sortilin, neurotensin receptor 3, BNR_2 PF13088.6 ORY11053.1 - 0.032 13.5 0.0 6.6 5.9 0.0 2.4 1 1 0 2 2 2 0 BNR repeat-like domain BNR PF02012.20 ORY11053.1 - 0.055 13.5 3.9 2.4 8.5 0.1 3.3 3 0 0 3 3 3 0 BNR/Asp-box repeat RTA1 PF04479.13 ORY11055.1 - 7e-75 251.2 8.9 1.1e-74 250.5 8.9 1.3 1 0 0 1 1 1 1 RTA1 like protein Zn_peptidase_2 PF04298.12 ORY11055.1 - 0.23 10.8 0.0 0.23 10.8 0.0 2.1 2 0 0 2 2 2 0 Putative neutral zinc metallopeptidase Zn_clus PF00172.18 ORY11056.1 - 4.4e-08 33.1 11.2 7.7e-08 32.3 11.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 ORY11056.1 - 1.1e-06 27.8 0.0 1.8e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Thiolase_N PF00108.23 ORY11058.1 - 1.6e-66 224.3 0.0 2.6e-66 223.7 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 ORY11058.1 - 2.1e-41 140.4 0.2 4e-41 139.5 0.2 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III PF08545.10 ORY11058.1 - 0.00012 21.9 0.3 0.02 14.7 0.0 2.4 2 0 0 2 2 2 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Abhydrolase_2 PF02230.16 ORY11059.1 - 3e-29 102.4 0.0 1.3e-22 80.7 0.0 2.2 2 1 0 2 2 2 2 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 ORY11059.1 - 2.9e-09 36.7 0.0 4.1e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 ORY11059.1 - 4.8e-06 26.0 0.0 0.0024 17.2 0.0 3.0 2 1 1 3 3 3 2 Serine aminopeptidase, S33 DLH PF01738.18 ORY11059.1 - 0.0044 16.6 0.0 0.0076 15.8 0.0 1.6 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 ORY11059.1 - 0.0086 15.7 0.0 0.013 15.1 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold BAAT_C PF08840.11 ORY11059.1 - 0.012 15.6 0.1 0.084 12.8 0.0 2.1 2 1 1 3 3 3 0 BAAT / Acyl-CoA thioester hydrolase C terminal Transcrip_act PF04949.13 ORY11059.1 - 0.018 14.9 1.3 0.033 14.1 1.3 1.3 1 0 0 1 1 1 0 Transcriptional activator Esterase PF00756.20 ORY11059.1 - 0.026 14.2 0.0 0.062 12.9 0.0 1.4 1 1 0 1 1 1 0 Putative esterase Cutinase PF01083.22 ORY11059.1 - 0.026 14.5 0.0 0.048 13.6 0.0 1.4 2 0 0 2 2 2 0 Cutinase Abhydrolase_6 PF12697.7 ORY11059.1 - 0.033 14.8 0.0 0.22 12.1 0.0 2.2 1 1 0 1 1 1 0 Alpha/beta hydrolase family FlaC_arch PF05377.11 ORY11059.1 - 0.036 14.4 2.0 0.11 12.9 1.2 2.0 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Esterase_phd PF10503.9 ORY11059.1 - 0.039 13.4 0.0 0.094 12.2 0.0 1.9 1 1 0 1 1 1 0 Esterase PHB depolymerase Gram_pos_anchor PF00746.21 ORY11060.1 - 0.077 13.0 0.1 0.22 11.5 0.1 1.8 1 0 0 1 1 1 0 LPXTG cell wall anchor motif ABC_membrane PF00664.23 ORY11062.1 - 9.3e-101 337.1 42.7 3.2e-54 184.4 14.5 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 ORY11062.1 - 1e-66 223.6 0.0 2.3e-32 112.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 ORY11062.1 - 4.2e-12 46.0 7.2 0.00039 19.9 0.0 4.1 2 2 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 ORY11062.1 - 4.6e-08 32.7 0.6 0.0041 16.8 0.6 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 ORY11062.1 - 5.9e-08 32.8 0.0 0.015 15.3 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 ORY11062.1 - 1.2e-07 32.1 0.7 0.054 13.8 0.1 3.9 2 2 0 2 2 2 2 AAA domain ABC_ATPase PF09818.9 ORY11062.1 - 7.4e-07 28.3 0.8 0.031 13.1 0.0 3.0 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_16 PF13191.6 ORY11062.1 - 3e-06 27.7 0.9 0.084 13.2 0.0 2.9 2 1 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 ORY11062.1 - 9.3e-06 25.7 0.3 0.33 10.7 0.0 4.2 3 1 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 ORY11062.1 - 2.4e-05 24.3 0.0 0.2 11.3 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain Zeta_toxin PF06414.12 ORY11062.1 - 0.00012 21.4 0.0 0.016 14.5 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin AAA_30 PF13604.6 ORY11062.1 - 0.00021 21.1 0.4 0.34 10.6 0.0 3.4 3 1 0 3 3 3 1 AAA domain AAA_25 PF13481.6 ORY11062.1 - 0.00025 20.7 0.2 0.72 9.4 0.1 2.9 3 0 0 3 3 2 2 AAA domain SbcCD_C PF13558.6 ORY11062.1 - 0.00029 21.0 1.4 1 9.6 0.2 4.0 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_28 PF13521.6 ORY11062.1 - 0.0008 19.7 0.0 0.46 10.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 ORY11062.1 - 0.0021 18.6 0.5 1.6 9.2 0.3 2.6 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 ORY11062.1 - 0.0038 17.8 0.0 2.8 8.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 ORY11062.1 - 0.0062 16.7 0.0 5.8 7.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 ORY11062.1 - 0.0064 16.0 0.0 1 8.8 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region G-alpha PF00503.20 ORY11062.1 - 0.01 15.1 0.0 3.1 6.8 0.0 2.4 2 0 0 2 2 2 0 G-protein alpha subunit AAA_5 PF07728.14 ORY11062.1 - 0.014 15.4 0.0 6.1 6.8 0.0 3.1 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Ploopntkinase3 PF18751.1 ORY11062.1 - 0.015 15.2 0.0 7.2 6.5 0.0 2.4 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 SRP54 PF00448.22 ORY11062.1 - 0.016 14.9 0.0 2.7 7.6 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain APS_kinase PF01583.20 ORY11062.1 - 0.018 15.0 0.0 0.84 9.5 0.0 2.7 2 0 0 2 2 2 0 Adenylylsulphate kinase MMR_HSR1 PF01926.23 ORY11062.1 - 0.022 14.9 0.0 7.4 6.7 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase NB-ARC PF00931.22 ORY11062.1 - 0.035 13.3 0.5 2.8 7.0 0.1 2.9 2 1 0 2 2 2 0 NB-ARC domain AAA_24 PF13479.6 ORY11062.1 - 0.054 13.2 0.0 10 5.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 ORY11062.1 - 0.073 13.5 0.0 7.5 7.0 0.0 2.5 2 0 0 2 2 2 0 RNA helicase Rad17 PF03215.15 ORY11062.1 - 0.11 12.4 0.0 2.5 8.0 0.0 2.6 2 0 0 2 2 2 0 Rad17 P-loop domain PRK PF00485.18 ORY11062.1 - 0.12 12.1 0.1 7.6 6.2 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Fungal_trans PF04082.18 ORY11063.1 - 8e-14 51.3 0.1 1.7e-13 50.2 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY11063.1 - 3.9e-08 33.3 13.0 8.2e-08 32.3 13.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain YEATS PF03366.16 ORY11064.1 - 1.9e-11 43.8 0.3 3.1e-11 43.1 0.3 1.3 1 0 0 1 1 1 1 YEATS family zf-C3HC4_2 PF13923.6 ORY11064.1 - 4.4e-06 26.4 5.2 4.4e-06 26.4 5.2 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 ORY11064.1 - 5.2e-06 26.5 4.3 5.2e-06 26.5 4.3 1.9 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 ORY11064.1 - 2.1e-05 24.5 5.7 2.1e-05 24.5 5.7 1.7 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 ORY11064.1 - 0.00013 22.2 9.7 0.00039 20.7 4.9 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 ORY11064.1 - 0.0003 20.6 4.9 0.0003 20.6 4.9 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 ORY11064.1 - 0.00072 19.4 9.3 0.0064 16.3 4.0 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORY11064.1 - 0.011 15.6 11.6 0.13 12.3 11.7 2.4 1 1 1 2 2 2 0 zinc-RING finger domain zf-RING_10 PF16685.5 ORY11064.1 - 0.13 12.4 7.2 0.31 11.2 4.4 2.1 2 0 0 2 2 2 0 zinc RING finger of MSL2 Prok-RING_4 PF14447.6 ORY11064.1 - 0.29 11.0 11.6 25 4.8 0.1 3.1 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 ORY11064.1 - 0.49 10.5 6.8 9.7 6.3 3.4 3.0 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 ORY11064.1 - 9.7 5.9 8.7 1.8 8.2 4.8 1.7 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type MFS_1 PF07690.16 ORY11065.1 - 2.6e-28 99.0 18.5 3.6e-28 98.5 18.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Wzy_C PF04932.15 ORY11065.1 - 8.9 5.9 10.6 1.6 8.4 0.2 3.0 3 1 0 3 3 3 0 O-Antigen ligase Asp PF00026.23 ORY11066.1 - 0.0091 15.4 0.0 0.072 12.5 0.0 2.0 1 1 0 1 1 1 1 Eukaryotic aspartyl protease S1FA PF04689.13 ORY11066.1 - 0.3 11.2 1.2 0.58 10.3 1.2 1.4 1 0 0 1 1 1 0 DNA binding protein S1FA Ank_2 PF12796.7 ORY11067.1 - 1e-25 90.1 0.2 1.2e-13 51.4 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY11067.1 - 1.5e-19 70.0 3.2 1.6e-07 31.7 0.5 4.4 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY11067.1 - 5e-17 60.2 3.7 0.00065 20.0 0.2 5.2 4 1 0 4 4 4 4 Ankyrin repeat Ank PF00023.30 ORY11067.1 - 4.6e-16 58.5 5.1 0.00015 22.0 0.1 4.3 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 ORY11067.1 - 6.2e-12 45.5 3.9 1.1e-05 25.6 0.1 3.9 2 2 2 4 4 4 3 Ankyrin repeats (many copies) SesA PF17107.5 ORY11067.1 - 0.025 14.8 0.2 0.14 12.4 0.2 2.4 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases TPR_16 PF13432.6 ORY11067.1 - 0.064 13.9 4.2 0.072 13.8 1.6 2.5 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 ORY11067.1 - 0.098 13.5 1.2 5.8 8.0 0.2 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Nuc_rec_co-act PF08815.10 ORY11067.1 - 0.32 10.9 2.1 1.7 8.5 0.2 2.9 3 0 0 3 3 3 0 Nuclear receptor coactivator Ion_trans PF00520.31 ORY11068.1 - 7.6e-09 35.2 22.2 3.9e-07 29.5 22.2 2.2 1 1 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 ORY11068.1 - 8.7e-07 28.0 21.4 4.4e-05 22.3 21.4 2.2 1 1 0 1 1 1 1 Polycystin cation channel SHP PF03579.13 ORY11068.1 - 0.065 13.2 0.1 0.26 11.3 0.1 2.0 1 0 0 1 1 1 0 Small hydrophobic protein EIF_2_alpha PF07541.12 ORY11069.1 - 9.4e-37 125.7 0.0 1.7e-36 124.8 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 ORY11069.1 - 1e-13 51.4 0.9 2e-13 50.5 0.9 1.5 1 0 0 1 1 1 1 S1 RNA binding domain Ion_trans_2 PF07885.16 ORY11072.1 - 1.5e-24 85.8 28.7 3.8e-14 52.4 5.6 2.9 3 0 0 3 3 3 2 Ion channel GWT1 PF06423.12 ORY11072.1 - 0.016 15.3 0.4 0.058 13.5 0.4 1.9 1 0 0 1 1 1 0 GWT1 Presenilin PF01080.17 ORY11072.1 - 0.073 11.8 0.1 0.073 11.8 0.1 2.1 2 0 0 2 2 2 0 Presenilin Ribophorin_II PF05817.14 ORY11073.1 - 0.065 11.8 0.6 0.13 10.7 0.6 1.5 1 0 0 1 1 1 0 Oligosaccharyltransferase subunit Ribophorin II DUF4746 PF15928.5 ORY11074.1 - 0.0042 16.6 8.3 0.0054 16.2 8.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4746) DUF5523 PF17661.1 ORY11074.1 - 0.18 11.5 8.7 0.22 11.2 8.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5523) VIR_N PF15912.5 ORY11074.1 - 0.33 10.5 4.1 0.4 10.2 4.1 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal PPP4R2 PF09184.11 ORY11074.1 - 0.49 9.9 5.3 0.56 9.8 5.3 1.1 1 0 0 1 1 1 0 PPP4R2 RR_TM4-6 PF06459.12 ORY11074.1 - 0.93 9.3 9.0 1.2 8.9 9.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PTPRCAP PF15713.5 ORY11074.1 - 5.6 7.3 15.6 7.5 6.8 15.6 1.1 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Presenilin PF01080.17 ORY11074.1 - 8.1 5.1 7.7 9.6 4.8 7.7 1.1 1 0 0 1 1 1 0 Presenilin PH_4 PF15404.6 ORY11075.1 - 5.2e-62 208.9 0.0 1.3e-61 207.6 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain Spo7_2_N PF15407.6 ORY11075.1 - 6.7e-24 83.3 1.5 6.7e-24 83.3 1.5 2.1 2 0 0 2 2 2 1 Sporulation protein family 7 PH PF00169.29 ORY11075.1 - 3.7e-10 40.3 0.0 0.094 13.2 0.0 5.5 4 1 0 4 4 4 2 PH domain PH_6 PF15406.6 ORY11075.1 - 0.0036 17.6 0.1 0.062 13.6 0.0 2.7 2 0 0 2 2 2 1 Pleckstrin homology domain ESCRT-II PF05871.12 ORY11075.1 - 0.0078 16.5 1.0 0.021 15.0 1.0 1.7 1 0 0 1 1 1 1 ESCRT-II complex subunit PH_11 PF15413.6 ORY11075.1 - 0.025 15.0 0.4 3.5 8.1 0.0 3.5 3 0 0 3 3 3 0 Pleckstrin homology domain PH_13 PF16652.5 ORY11075.1 - 0.14 12.0 0.2 12 5.6 0.0 2.6 2 0 0 2 2 2 0 Pleckstrin homology domain PP2C PF00481.21 ORY11083.1 - 2.8e-83 279.5 0.3 4.9e-83 278.7 0.0 1.4 2 0 0 2 2 2 1 Protein phosphatase 2C FMN_dh PF01070.18 ORY11084.1 - 6.9e-32 110.8 0.8 4.2e-15 55.6 0.0 2.9 1 1 3 4 4 4 3 FMN-dependent dehydrogenase Glu_synthase PF01645.17 ORY11084.1 - 0.2 10.8 0.0 0.28 10.3 0.0 1.1 1 0 0 1 1 1 0 Conserved region in glutamate synthase WD40 PF00400.32 ORY11085.1 - 6.6e-37 124.9 23.1 3.4e-10 40.4 0.4 7.9 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY11085.1 - 9.2e-13 48.3 0.9 0.0014 18.9 0.1 5.2 2 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ORY11085.1 - 1.5e-08 33.8 6.9 0.027 13.1 0.1 4.8 3 2 1 5 5 5 4 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 ORY11085.1 - 2.3e-08 33.4 0.6 0.092 11.7 0.0 4.3 2 2 2 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein PALB2_WD40 PF16756.5 ORY11085.1 - 0.0004 19.4 0.1 0.0004 19.4 0.1 2.7 3 1 1 4 4 4 1 Partner and localizer of BRCA2 WD40 domain DUF1513 PF07433.11 ORY11085.1 - 0.00072 18.7 2.7 2.5 7.1 0.1 3.8 1 1 3 4 4 4 3 Protein of unknown function (DUF1513) Hira PF07569.11 ORY11085.1 - 0.0016 18.2 0.5 4 7.1 0.0 3.2 1 1 2 3 3 3 2 TUP1-like enhancer of split Frtz PF11768.8 ORY11085.1 - 0.012 14.0 0.0 0.021 13.2 0.0 1.5 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz Coatomer_WDAD PF04053.14 ORY11085.1 - 0.053 12.6 0.0 0.069 12.2 0.0 1.2 1 0 0 1 1 1 0 Coatomer WD associated region Nucleoporin_N PF08801.11 ORY11085.1 - 0.07 11.9 0.1 2.8 6.6 0.0 2.9 1 1 0 2 2 2 0 Nup133 N terminal like Sugar_tr PF00083.24 ORY11086.1 - 3.5e-94 316.2 16.9 2.1e-93 313.7 16.9 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY11086.1 - 2.9e-24 85.6 25.9 2.9e-24 85.6 25.9 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily LacY_symp PF01306.19 ORY11086.1 - 0.049 12.4 9.2 0.26 10.0 2.7 2.7 2 1 0 2 2 2 0 LacY proton/sugar symporter ABC_tran_CTD PF16326.5 ORY11087.1 - 0.054 13.8 4.7 0.093 13.0 4.7 1.3 1 0 0 1 1 1 0 ABC transporter C-terminal domain HET PF06985.11 ORY11088.1 - 5.3e-27 95.0 0.1 1.1e-26 93.9 0.1 1.6 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) CTV_P6 PF06706.11 ORY11088.1 - 0.21 11.3 0.8 0.51 10.1 0.8 1.6 1 0 0 1 1 1 0 Citrus tristeza virus 6-kDa protein Metallophos_2 PF12850.7 ORY11089.1 - 1.7e-10 41.4 0.0 2.7e-10 40.7 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 ORY11089.1 - 0.12 12.8 0.0 0.18 12.3 0.0 1.4 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase Inositol_P PF00459.25 ORY11090.1 - 3.9e-41 141.4 0.1 1.2e-32 113.6 0.0 2.2 2 0 0 2 2 2 2 Inositol monophosphatase family DUF4229 PF14012.6 ORY11091.1 - 0.11 12.6 0.1 0.23 11.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4229) Ecl1 PF12855.7 ORY11092.1 - 1.9e-15 58.5 17.3 2.3e-15 58.2 17.3 1.1 1 0 0 1 1 1 1 ECL1/2/3 zinc binding proteins PLATZ PF04640.14 ORY11092.1 - 0.64 10.7 3.4 0.3 11.7 1.1 1.7 2 0 0 2 2 2 0 PLATZ transcription factor FAM199X PF15814.5 ORY11092.1 - 4.4 6.3 8.9 0.23 10.5 3.6 1.5 2 0 0 2 2 2 0 Protein family FAM199X Aminotran_5 PF00266.19 ORY11095.1 - 8.6e-30 103.9 0.0 1.1e-29 103.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V IKI3 PF04762.12 ORY11096.1 - 1.8e-300 999.3 0.0 2.2e-300 999.0 0.0 1.1 1 0 0 1 1 1 1 IKI3 family ANAPC4_WD40 PF12894.7 ORY11096.1 - 0.0025 18.1 0.2 1.6 9.1 0.0 3.8 2 1 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain COX7C PF02935.16 ORY11097.1 - 1.5e-24 86.0 1.0 1.8e-24 85.7 1.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc rRNA_proc-arch PF13234.6 ORY11098.1 - 1.6e-88 297.2 0.5 3.8e-88 295.9 0.1 1.9 2 0 0 2 2 2 1 rRNA-processing arch domain DSHCT PF08148.12 ORY11098.1 - 5.2e-55 185.6 1.9 2.4e-54 183.4 1.3 2.3 2 0 0 2 2 2 1 DSHCT (NUC185) domain DEAD PF00270.29 ORY11098.1 - 8.3e-19 68.0 0.1 4.8e-18 65.5 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY11098.1 - 1e-06 29.0 0.0 4.8e-06 26.9 0.0 2.1 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY11098.1 - 9.6e-06 25.7 0.0 3.3e-05 23.9 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit T2SSE PF00437.20 ORY11098.1 - 0.0024 17.0 0.0 0.044 12.8 0.0 2.5 2 0 0 2 2 2 1 Type II/IV secretion system protein ATPase_2 PF01637.18 ORY11098.1 - 0.018 14.9 0.2 0.1 12.5 0.0 2.3 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_22 PF13401.6 ORY11098.1 - 0.023 15.0 0.1 0.18 12.1 0.0 2.6 2 1 0 2 2 2 0 AAA domain DUF5388 PF17363.2 ORY11098.1 - 0.042 14.0 0.2 0.34 11.1 0.0 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5388) Prp19 PF08606.11 ORY11098.1 - 0.25 11.4 2.8 21 5.2 0.1 3.0 3 0 0 3 3 3 0 Prp19/Pso4-like Cut8 PF08559.10 ORY11099.1 - 3.4e-81 272.4 0.0 4.3e-81 272.1 0.0 1.0 1 0 0 1 1 1 1 Cut8, nuclear proteasome tether protein DUF2464 PF10240.9 ORY11100.1 - 0.0033 17.0 0.0 0.0061 16.2 0.0 1.4 1 1 0 1 1 1 1 Multivesicular body subunit 12 adh_short PF00106.25 ORY11102.1 - 1.6e-46 158.2 0.1 2e-46 157.9 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY11102.1 - 4e-36 124.7 0.0 5.2e-36 124.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY11102.1 - 3.4e-12 46.6 0.1 5.1e-12 46.1 0.1 1.3 1 0 0 1 1 1 1 KR domain T4SS-DNA_transf PF02534.14 ORY11102.1 - 0.00071 18.5 0.0 0.00092 18.1 0.0 1.1 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer THF_DHG_CYH_C PF02882.19 ORY11102.1 - 0.0054 16.1 0.8 0.023 14.0 0.2 2.0 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.21 ORY11102.1 - 0.0055 16.2 0.0 0.0096 15.4 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 ORY11102.1 - 0.021 14.7 0.2 0.033 14.1 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_25 PF13649.6 ORY11102.1 - 0.052 14.3 0.1 0.13 13.0 0.1 1.6 1 0 0 1 1 1 0 Methyltransferase domain B12-binding PF02310.19 ORY11102.1 - 0.13 12.3 0.1 0.25 11.4 0.1 1.4 1 0 0 1 1 1 0 B12 binding domain Sacchrp_dh_NADP PF03435.18 ORY11102.1 - 0.14 12.4 0.2 0.24 11.6 0.2 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain CLIP PF12032.8 ORY11103.1 - 0.93 9.8 23.0 6.2 7.2 0.5 5.2 6 0 0 6 6 6 0 Regulatory CLIP domain of proteinases MFS_1 PF07690.16 ORY11105.1 - 1.1e-43 149.5 43.7 1.1e-43 149.5 43.7 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY11105.1 - 5.9e-12 45.2 24.2 1.2e-11 44.2 24.1 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.20 ORY11105.1 - 0.00049 18.5 4.6 0.00049 18.5 4.6 2.3 1 1 2 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family Fungal_trans PF04082.18 ORY11106.1 - 8.5e-15 54.5 0.0 1.5e-14 53.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY11106.1 - 3.2e-08 33.6 8.8 5.4e-08 32.8 8.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HSBP1 PF06825.12 ORY11106.1 - 0.047 13.5 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 Heat shock factor binding protein 1 p450 PF00067.22 ORY11107.1 - 9.3e-31 107.1 0.0 1e-30 106.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 UbiA PF01040.18 ORY11108.1 - 5.7e-21 74.9 7.5 1.1e-20 74.1 7.5 1.4 1 0 0 1 1 1 1 UbiA prenyltransferase family p450 PF00067.22 ORY11108.1 - 0.00021 20.2 0.0 0.00041 19.2 0.0 1.4 2 0 0 2 2 2 1 Cytochrome P450 PspB PF06667.12 ORY11109.1 - 0.21 11.7 0.3 0.21 11.7 0.3 1.9 2 0 0 2 2 2 0 Phage shock protein B DUF3649 PF12365.8 ORY11109.1 - 0.3 10.8 0.2 0.3 10.8 0.2 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF3649) FAD_binding_4 PF01565.23 ORY11110.1 - 1.1e-20 73.8 0.3 2.4e-20 72.7 0.3 1.6 2 0 0 2 2 2 1 FAD binding domain Tautomerase_3 PF14832.6 ORY11111.1 - 2e-52 177.1 0.0 2.3e-52 176.9 0.0 1.0 1 0 0 1 1 1 1 Putative oxalocrotonate tautomerase enzyme NmrA PF05368.13 ORY11112.1 - 5.4e-20 72.0 0.0 6.8e-20 71.6 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ORY11112.1 - 2.3e-05 24.4 0.0 3.1e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 ORY11112.1 - 0.0091 15.5 0.0 0.13 11.7 0.0 2.5 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 ORY11112.1 - 0.013 15.9 0.1 0.062 13.7 0.0 2.1 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain PHO4 PF01384.20 ORY11113.1 - 3.7e-100 335.2 19.7 4.3e-100 335.0 19.7 1.0 1 0 0 1 1 1 1 Phosphate transporter family UPF0444 PF15475.6 ORY11113.1 - 1 9.7 9.0 1.1 9.6 0.8 2.9 2 0 0 2 2 2 0 Transmembrane protein C12orf23, UPF0444 Acyl-CoA_dh_1 PF00441.24 ORY11114.1 - 2.3e-28 99.3 0.0 3e-28 98.9 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 ORY11114.1 - 2.1e-21 75.9 0.0 3.5e-21 75.2 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 ORY11114.1 - 2.5e-14 53.9 0.2 1.2e-13 51.7 0.0 2.2 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 ORY11114.1 - 0.0006 20.1 0.0 0.001 19.3 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Protoglobin PF11563.8 ORY11115.1 - 2.4e-60 203.0 0.0 2.9e-60 202.7 0.0 1.1 1 0 0 1 1 1 1 Protoglobin DUF629 PF04780.12 ORY11116.1 - 0.3 9.6 0.4 0.51 8.8 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF629) DUF1242 PF06842.12 ORY11118.1 - 1.9e-14 53.1 0.2 2.6e-14 52.7 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) TFIID-18kDa PF02269.16 ORY11119.1 - 2.1e-26 91.8 0.0 2.8e-26 91.4 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit CENP-S PF15630.6 ORY11119.1 - 0.00028 21.2 0.0 0.0005 20.4 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein TFIID_20kDa PF03847.13 ORY11119.1 - 0.01 16.3 0.2 0.018 15.5 0.2 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A CENP-T_C PF15511.6 ORY11119.1 - 0.038 14.1 0.0 0.05 13.7 0.0 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold DNA_pol_phi PF04931.13 ORY11119.1 - 3.4 5.7 4.3 4.4 5.3 4.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi MitMem_reg PF13012.6 ORY11120.1 - 6.8e-20 71.6 0.6 1.2e-19 70.8 0.6 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 ORY11120.1 - 3.4e-19 68.9 0.0 5.3e-19 68.3 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease UPF0172 PF03665.13 ORY11120.1 - 0.0014 18.7 0.0 0.003 17.6 0.0 1.5 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0172) UTP25 PF06862.12 ORY11121.1 - 1.4e-174 581.4 0.0 1.7e-174 581.1 0.0 1.1 1 0 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Cas_csx3 PF09620.10 ORY11121.1 - 0.077 12.9 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_csx3) HET PF06985.11 ORY11122.1 - 7.4e-33 114.0 0.7 1.1e-32 113.4 0.7 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF4003 PF13170.6 ORY11122.1 - 0.045 13.1 0.0 0.1 11.9 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4003) Pro-kuma_activ PF09286.11 ORY11123.1 - 1.6e-38 132.2 0.1 2.5e-38 131.5 0.1 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 ORY11123.1 - 2.2e-07 30.4 0.4 6.8e-07 28.8 0.1 1.9 2 1 0 2 2 2 1 Subtilase family zf-RAG1 PF10426.9 ORY11123.1 - 0.13 12.4 0.9 0.27 11.4 0.9 1.5 1 0 0 1 1 1 0 Recombination-activating protein 1 zinc-finger domain GSDH PF07995.11 ORY11125.1 - 5.7e-05 22.6 2.8 0.00036 19.9 1.3 2.7 2 1 0 2 2 2 1 Glucose / Sorbosone dehydrogenase SGL PF08450.12 ORY11125.1 - 0.0057 16.3 0.1 0.038 13.6 0.0 2.1 2 1 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region PD40 PF07676.12 ORY11125.1 - 0.012 15.5 0.7 0.054 13.5 0.0 2.5 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Arylesterase PF01731.20 ORY11125.1 - 0.11 12.7 0.0 5 7.4 0.0 2.5 2 0 0 2 2 2 0 Arylesterase HET PF06985.11 ORY11126.1 - 3.3e-31 108.6 0.0 1.7e-30 106.3 0.0 2.2 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) adh_short PF00106.25 ORY11127.1 - 0.002 17.6 0.0 0.067 12.6 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase BBE PF08031.12 ORY11128.1 - 0.00042 20.4 0.1 0.00052 20.1 0.1 1.1 1 0 0 1 1 1 1 Berberine and berberine like DnaJ PF00226.31 ORY11129.1 - 5.6e-20 71.2 0.3 8.4e-20 70.7 0.3 1.3 1 0 0 1 1 1 1 DnaJ domain DUF1980 PF09323.10 ORY11130.1 - 1.4 8.8 5.9 8.8 6.2 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) ATP-grasp_6 PF18419.1 ORY11131.1 - 0.041 13.5 0.5 3 7.6 0.0 3.2 3 0 0 3 3 3 0 ATP-grasp-like domain adh_short PF00106.25 ORY11133.1 - 1.2e-10 41.2 0.3 2.8e-10 40.0 0.2 1.6 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 ORY11133.1 - 7.1e-08 32.6 0.0 2.3e-07 30.9 0.0 1.8 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.6 ORY11133.1 - 1.2e-05 25.0 0.3 3.6e-05 23.4 0.1 1.8 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase DUF1364 PF07102.12 ORY11134.1 - 0.14 12.0 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1364) DAO PF01266.24 ORY11139.1 - 5e-29 102.0 0.2 6.5e-29 101.6 0.2 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ORY11139.1 - 0.052 13.8 0.0 0.23 11.7 0.0 2.2 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HET PF06985.11 ORY11140.1 - 4.5e-30 104.9 0.0 7.8e-30 104.1 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MULE PF10551.9 ORY11142.1 - 0.011 16.1 0.0 0.013 15.9 0.0 1.1 1 0 0 1 1 1 0 MULE transposase domain COesterase PF00135.28 ORY11146.1 - 1.6e-55 188.9 0.0 2.2e-55 188.5 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 ORY11146.1 - 0.00031 20.7 0.0 0.046 13.6 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold MFS_1 PF07690.16 ORY11147.1 - 1.7e-14 53.5 27.8 3.2e-12 46.0 15.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily 2-Hacid_dh_C PF02826.19 ORY11148.1 - 3.3e-33 114.5 0.0 4.7e-33 114.0 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 ORY11148.1 - 0.0046 17.5 0.0 0.0084 16.7 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Bim_N PF06773.11 ORY11149.1 - 2.3 8.0 0.0 2.3 8.0 0.0 2.6 3 0 0 3 3 3 0 Bim protein N-terminus Fungal_trans PF04082.18 ORY11153.1 - 3.1e-13 49.4 4.6 5.2e-13 48.6 4.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY11153.1 - 0.0031 17.6 12.3 0.0031 17.6 12.3 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain STE2 PF02116.15 ORY11154.1 - 0.065 12.5 20.6 0.47 9.7 11.2 2.2 1 1 0 2 2 2 0 Fungal pheromone mating factor STE2 GPCR DUF3325 PF11804.8 ORY11154.1 - 0.97 9.6 8.7 0.19 11.9 1.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3325) DUF423 PF04241.15 ORY11154.1 - 2.3 8.5 5.5 2 8.7 0.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF423) Fungal_trans PF04082.18 ORY11155.1 - 4e-18 65.4 0.1 6.8e-18 64.7 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY11155.1 - 5.6e-07 29.6 8.1 9.7e-07 28.8 8.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aminotran_4 PF01063.19 ORY11157.1 - 4.3e-23 82.4 0.0 5.9e-23 81.9 0.0 1.2 1 0 0 1 1 1 1 Amino-transferase class IV PARM PF17061.5 ORY11157.1 - 0.89 9.6 4.3 1.4 9.0 4.3 1.2 1 0 0 1 1 1 0 PARM DUF679 PF05078.12 ORY11158.1 - 0.039 13.9 0.2 0.12 12.4 0.1 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF679) TraE PF05309.11 ORY11158.1 - 0.049 13.0 1.7 0.054 12.9 0.1 1.8 2 0 0 2 2 2 0 TraE protein DUF4423 PF14394.6 ORY11158.1 - 0.05 13.3 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) HTH_20 PF12840.7 ORY11158.1 - 0.086 12.9 0.7 0.21 11.7 0.1 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain DUF1360 PF07098.11 ORY11158.1 - 0.087 12.8 0.5 0.45 10.5 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1360) DUF2721 PF11026.8 ORY11158.1 - 0.64 9.9 4.4 0.46 10.4 0.2 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2721) Corona_nucleoca PF00937.18 ORY11159.1 - 0.58 9.1 3.7 0.89 8.5 3.7 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein MBOAT_2 PF13813.6 ORY11160.1 - 1.1e-12 48.1 1.4 2.4e-12 46.9 1.4 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Form_Nir_trans PF01226.17 ORY11160.1 - 0.041 13.2 5.7 0.098 12.0 5.7 1.6 1 0 0 1 1 1 0 Formate/nitrite transporter Methyltransf_23 PF13489.6 ORY11164.1 - 9.8e-20 71.0 0.0 1.7e-19 70.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY11164.1 - 5.8e-10 39.8 0.0 2.2e-09 37.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY11164.1 - 2.8e-07 31.1 0.0 6.4e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY11164.1 - 2.2e-05 24.3 0.0 0.2 11.4 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 ORY11164.1 - 6.6e-05 23.6 0.0 0.00063 20.4 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ORY11164.1 - 0.013 15.1 0.0 0.022 14.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Ubie_methyltran PF01209.18 ORY11164.1 - 0.075 12.4 0.0 2 7.7 0.0 2.4 3 0 0 3 3 3 0 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 ORY11164.1 - 0.11 12.0 0.8 0.24 10.9 0.0 2.0 3 0 0 3 3 3 0 Putative methyltransferase GidB PF02527.15 ORY11164.1 - 0.12 11.7 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G CheR PF01739.18 ORY11164.1 - 0.18 11.3 0.0 0.34 10.4 0.0 1.4 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain CHD5 PF04420.14 ORY11167.1 - 3.1e-58 196.1 0.5 3.9e-58 195.8 0.5 1.1 1 0 0 1 1 1 1 CHD5-like protein PPTA PF01239.22 ORY11168.1 - 8.4e-09 34.9 1.8 0.0026 17.4 0.0 2.8 2 0 0 2 2 2 2 Protein prenyltransferase alpha subunit repeat SepRS_C PF18006.1 ORY11168.1 - 0.11 12.6 0.0 0.25 11.5 0.0 1.6 1 0 0 1 1 1 0 O-phosphoseryl-tRNA synthetase C-terminal domain zf-C2H2 PF00096.26 ORY11192.1 - 1.3e-12 47.4 14.0 7.1e-07 29.3 1.4 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY11192.1 - 4.1e-08 33.4 11.6 0.00067 20.3 0.6 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORY11192.1 - 4.6e-06 26.8 14.4 2.3e-05 24.6 6.1 3.4 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.8 ORY11192.1 - 1.5e-05 25.1 8.8 0.011 16.0 1.1 2.8 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ORY11192.1 - 8.2e-05 22.9 6.7 0.0057 17.0 0.3 2.9 3 0 0 3 3 2 2 Zinc-finger of C2H2 type zf-LYAR PF08790.11 ORY11192.1 - 0.014 15.3 4.1 0.61 10.0 0.7 2.8 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-C2H2_6 PF13912.6 ORY11192.1 - 0.015 15.3 12.5 0.11 12.6 1.4 2.6 2 1 0 2 2 2 0 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 ORY11192.1 - 0.038 13.6 3.9 0.81 9.4 1.7 2.4 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain LIM PF00412.22 ORY11192.1 - 0.058 13.6 3.3 0.14 12.4 3.3 1.7 1 1 0 1 1 1 0 LIM domain DUF2613 PF11021.8 ORY11192.1 - 0.097 12.8 0.0 0.32 11.1 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) zf-UBR PF02207.20 ORY11192.1 - 0.2 11.9 1.9 0.39 10.9 1.9 1.4 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) zf-C2H2_11 PF16622.5 ORY11192.1 - 0.35 10.7 9.8 1.5 8.7 0.2 2.4 2 0 0 2 2 2 0 zinc-finger C2H2-type zf_UBZ PF18439.1 ORY11192.1 - 0.46 10.1 2.8 0.96 9.1 0.3 2.3 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger CDC45 PF02724.14 ORY11192.1 - 1.6 6.9 8.8 2.1 6.5 8.8 1.1 1 0 0 1 1 1 0 CDC45-like protein zf-BED PF02892.15 ORY11192.1 - 2 8.5 6.8 0.95 9.5 2.6 2.3 1 1 1 2 2 2 0 BED zinc finger zf-C2H2_3rep PF18868.1 ORY11192.1 - 2.1 9.0 7.7 4.7 7.9 0.4 3.0 1 1 2 3 3 3 0 Zinc finger C2H2-type, 3 repeats DTHCT PF08070.11 ORY11192.1 - 2.8 8.7 10.1 10 6.9 10.0 2.0 1 1 0 1 1 1 0 DTHCT (NUC029) region Zn-ribbon_8 PF09723.10 ORY11192.1 - 4.1 7.6 6.8 4 7.6 0.7 3.2 2 1 1 3 3 2 0 Zinc ribbon domain zf-C2HE PF16278.5 ORY11192.1 - 4.8 7.7 7.2 24 5.5 0.8 2.7 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger PITH PF06201.13 ORY11194.1 - 1.5e-38 132.4 0.0 3.4e-38 131.2 0.0 1.6 2 0 0 2 2 2 1 PITH domain Thioredoxin PF00085.20 ORY11194.1 - 6.3e-20 71.1 0.0 1.4e-19 70.0 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin HyaE PF07449.11 ORY11194.1 - 0.0037 17.2 0.0 0.0089 16.0 0.0 1.6 1 0 0 1 1 1 1 Hydrogenase-1 expression protein HyaE OST3_OST6 PF04756.13 ORY11194.1 - 0.0044 16.4 0.0 0.0072 15.7 0.0 1.3 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 ORY11194.1 - 0.006 17.0 0.0 0.013 15.9 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like domain DIM1 PF02966.16 ORY11194.1 - 0.014 15.2 0.0 0.024 14.4 0.0 1.3 1 0 0 1 1 1 0 Mitosis protein DIM1 TraF PF13728.6 ORY11194.1 - 0.052 13.4 0.1 0.09 12.6 0.1 1.3 1 0 0 1 1 1 0 F plasmid transfer operon protein Thioredoxin_8 PF13905.6 ORY11194.1 - 0.089 13.1 0.2 4.2 7.8 0.0 2.3 1 1 1 2 2 2 0 Thioredoxin-like TUG-UBL1 PF11470.8 ORY11195.1 - 1.5e-23 82.8 0.3 5.4e-22 77.8 0.1 2.9 3 0 0 3 3 3 1 TUG ubiquitin-like domain UBX PF00789.20 ORY11195.1 - 4.4e-06 26.8 0.0 6.6e-05 23.0 0.0 2.6 2 0 0 2 2 2 1 UBX domain ubiquitin PF00240.23 ORY11195.1 - 8.6e-05 22.2 0.0 0.00071 19.3 0.0 2.6 3 0 0 3 3 3 1 Ubiquitin family DraK_HK_N PF18092.1 ORY11195.1 - 0.006 17.0 0.6 0.014 15.8 0.6 1.6 1 0 0 1 1 1 1 DraK Histidine Kinase N-terminal domain PB1 PF00564.24 ORY11195.1 - 0.044 13.7 0.0 16 5.5 0.0 3.2 3 0 0 3 3 3 0 PB1 domain DUF4974 PF16344.5 ORY11195.1 - 0.073 13.1 0.0 1.3 9.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4974) Ribosomal_L36e PF01158.18 ORY11196.1 - 2.3e-40 136.7 3.4 2.7e-40 136.5 3.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e 4HBT_3 PF13622.6 ORY11197.1 - 5.4e-54 184.1 0.0 6.1e-54 183.9 0.0 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 ORY11197.1 - 0.0039 17.5 0.2 1 9.8 0.1 2.3 2 0 0 2 2 2 2 Thioesterase superfamily AMP-binding PF00501.28 ORY11198.1 - 7.6e-104 347.6 0.0 9e-104 347.4 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORY11198.1 - 4.4e-14 53.2 0.4 1e-13 52.1 0.4 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF535 PF04393.13 ORY11201.1 - 0.079 12.2 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF535) FokI_C PF02980.16 ORY11201.1 - 0.22 11.5 0.0 0.34 10.9 0.0 1.2 1 0 0 1 1 1 0 Restriction endonuclease FokI, catalytic domain C2 PF00168.30 ORY11202.1 - 8.5e-11 42.1 0.0 1.8e-10 41.0 0.0 1.6 1 0 0 1 1 1 1 C2 domain Pex14_N PF04695.13 ORY11202.1 - 1 10.0 5.3 3.4 8.3 1.6 2.5 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SnoaL_4 PF13577.6 ORY11203.1 - 3.5e-25 88.6 0.0 4.3e-25 88.3 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain DUF3225 PF11533.8 ORY11203.1 - 0.0018 18.0 0.0 0.0024 17.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3225) SnoaL_2 PF12680.7 ORY11203.1 - 0.0044 17.6 0.0 0.0056 17.3 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 ORY11203.1 - 0.029 14.8 0.0 0.037 14.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) SnoaL PF07366.12 ORY11203.1 - 0.068 13.0 0.0 0.092 12.5 0.0 1.3 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase DUF2235 PF09994.9 ORY11204.1 - 5.6e-102 341.0 0.0 7.1e-102 340.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Autophagy_C PF10381.9 ORY11204.1 - 0.23 11.0 1.1 0.43 10.1 1.1 1.4 1 0 0 1 1 1 0 Autophagocytosis associated protein C-terminal An_peroxidase PF03098.15 ORY11205.1 - 5.7e-43 147.3 0.0 1.8e-22 79.7 0.0 3.3 1 1 2 3 3 3 3 Animal haem peroxidase p450 PF00067.22 ORY11205.1 - 1.1e-05 24.4 0.1 0.00013 20.9 0.0 2.1 2 0 0 2 2 2 1 Cytochrome P450 Collagen PF01391.18 ORY11205.1 - 0.038 13.7 15.0 0.077 12.8 15.0 1.4 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) Proteasome PF00227.26 ORY11206.1 - 7.3e-30 103.9 0.2 3.2e-29 101.8 0.1 1.9 2 0 0 2 2 2 1 Proteasome subunit HCNGP PF07818.13 ORY11207.1 - 1e-24 87.0 0.2 1.7e-24 86.3 0.2 1.4 1 0 0 1 1 1 1 HCNGP-like protein Proteasome PF00227.26 ORY11208.1 - 8.1e-30 103.7 0.0 9.8e-30 103.5 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit MARVEL PF01284.23 ORY11209.1 - 5.2e-11 42.8 12.1 1e-10 41.8 12.1 1.4 1 0 0 1 1 1 1 Membrane-associating domain Claudin_3 PF06653.11 ORY11209.1 - 4.3 7.2 9.5 0.62 10.0 3.1 2.3 2 1 0 2 2 2 0 Tight junction protein, Claudin-like VCPO_N PF17897.1 ORY11210.1 - 1.1e-95 319.5 0.8 2.7e-95 318.2 0.9 1.6 2 0 0 2 2 2 1 Vanadium chloroperoxidase N-terminal domain PAP2 PF01569.21 ORY11210.1 - 1.5e-07 31.2 0.7 1.6e-06 27.9 0.7 2.2 1 1 0 1 1 1 1 PAP2 superfamily RRM_1 PF00076.22 ORY11211.1 - 5.4e-09 35.8 0.0 8.6e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 ORY11211.1 - 0.00039 20.0 0.0 0.00052 19.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_60s PF00428.19 ORY11211.1 - 0.085 13.5 6.9 0.13 12.8 6.9 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein WD40 PF00400.32 ORY11212.1 - 8.1e-15 55.0 12.3 0.00024 21.9 0.0 6.6 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY11212.1 - 5.5e-07 29.8 0.0 0.088 13.1 0.0 4.8 5 1 1 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 ORY11212.1 - 0.0054 16.7 0.1 0.84 9.6 0.0 3.1 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 ORY11212.1 - 0.082 11.8 0.0 18 4.2 0.0 3.0 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein zf-LYAR PF08790.11 ORY11214.1 - 1.8e-14 53.3 4.5 1.8e-14 53.3 4.5 2.4 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger Prok-RING_1 PF14446.6 ORY11214.1 - 1.3 9.0 4.4 3.4 7.7 4.4 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Evr1_Alr PF04777.13 ORY11215.1 - 6.9e-27 93.8 0.1 9.3e-27 93.4 0.1 1.2 1 0 0 1 1 1 1 Erv1 / Alr family Aminotran_4 PF01063.19 ORY11216.1 - 9.2e-24 84.5 0.0 1.1e-23 84.2 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV EphA2_TM PF14575.6 ORY11217.1 - 0.001 19.9 0.6 0.022 15.6 0.0 2.6 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain Zn_clus PF00172.18 ORY11218.1 - 4.3e-05 23.6 7.8 9e-05 22.5 7.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ORY11218.1 - 0.0025 16.9 0.0 0.0048 16.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Peptidase_C48 PF02902.19 ORY11219.1 - 4.2e-17 62.7 0.1 2.1e-16 60.4 0.1 2.0 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DUF4951 PF16309.5 ORY11219.1 - 0.085 12.9 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 Domian of unknown function (DUF4951) Glyco_hydro_61 PF03443.14 ORY11221.1 - 8.3e-43 146.7 0.0 1e-42 146.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 MFS_1 PF07690.16 ORY11222.1 - 1.6e-40 139.1 42.4 2.3e-40 138.6 42.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 ORY11222.1 - 1.1e-09 37.3 20.4 1.5e-09 36.8 20.4 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 ORY11222.1 - 4.2e-07 29.2 28.9 7.1e-06 25.1 13.8 2.6 3 0 0 3 3 3 2 Sugar (and other) transporter RNase_P_pop3 PF08228.11 ORY11222.1 - 0.1 12.6 0.2 1.2 9.2 0.0 2.1 2 0 0 2 2 2 0 RNase P subunit Pop3 MFS_1 PF07690.16 ORY11223.1 - 1.7e-34 119.3 27.2 2.6e-34 118.7 27.2 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily WD40 PF00400.32 ORY11224.1 - 2.1e-62 205.6 35.8 3.8e-11 43.3 0.2 9.4 9 1 0 9 9 9 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY11224.1 - 7.2e-25 87.1 1.5 4.2e-05 23.8 0.0 6.7 2 2 5 7 7 7 7 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 ORY11224.1 - 2.9e-07 29.8 0.3 0.016 14.1 0.0 4.8 4 2 2 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 ORY11224.1 - 5.4e-06 25.9 0.2 0.16 11.3 0.0 4.2 3 1 1 4 4 4 2 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 ORY11224.1 - 0.00023 20.0 7.5 0.86 8.2 0.1 5.0 4 2 2 6 6 6 3 Nucleoporin Nup120/160 PD40 PF07676.12 ORY11224.1 - 0.0023 17.8 0.2 16 5.6 0.0 4.6 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat DUF5046 PF16465.5 ORY11224.1 - 0.05 13.0 0.0 7.8 5.9 0.0 3.4 2 2 2 4 4 4 0 Domain of unknown function (DUF5046) Kelch_6 PF13964.6 ORY11224.1 - 0.11 12.8 0.1 3.1 8.2 0.0 3.3 4 0 0 4 4 4 0 Kelch motif Proteasome_A_N PF10584.9 ORY11224.1 - 0.29 10.9 1.3 93 2.8 0.0 4.4 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature MutS_V PF00488.21 ORY11225.1 - 9.5e-65 218.2 0.5 1.8e-64 217.3 0.5 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 ORY11225.1 - 5.8e-33 114.7 1.5 5.8e-33 114.7 1.5 1.7 2 0 0 2 2 2 1 MutS domain III MutS_II PF05188.17 ORY11225.1 - 5e-11 43.0 0.1 1.3e-10 41.7 0.1 1.7 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 ORY11225.1 - 6.6e-09 36.0 0.3 1.5e-08 34.9 0.3 1.7 1 0 0 1 1 1 1 MutS family domain IV TFIIS_M PF07500.14 ORY11225.1 - 0.014 15.9 0.4 0.063 13.8 0.1 2.3 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS), central domain AAA_27 PF13514.6 ORY11225.1 - 0.023 14.3 0.0 1.4 8.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 ORY11225.1 - 0.16 11.7 1.4 0.22 11.2 0.1 1.9 2 0 0 2 2 2 0 AAA domain DUF4272 PF14094.6 ORY11225.1 - 0.16 11.2 0.5 2.1 7.5 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4272) MnmE_helical PF12631.7 ORY11225.1 - 1.3 9.1 4.2 0.71 10.0 0.3 2.3 2 1 1 3 3 3 0 MnmE helical domain NMO PF03060.15 ORY11226.1 - 4.1e-25 88.9 11.4 2.8e-20 73.0 7.7 2.1 2 0 0 2 2 2 2 Nitronate monooxygenase IMPDH PF00478.25 ORY11226.1 - 2.3e-05 23.6 8.5 0.083 11.9 0.1 2.3 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 ORY11226.1 - 0.0017 17.6 3.5 0.0025 17.0 3.5 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase FMN_dh PF01070.18 ORY11226.1 - 0.014 14.4 6.9 0.019 14.0 6.9 1.1 1 0 0 1 1 1 0 FMN-dependent dehydrogenase RRS1 PF04939.12 ORY11227.1 - 4.4e-61 205.5 2.4 5.4e-61 205.2 2.4 1.1 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) DAP3 PF10236.9 ORY11228.1 - 3.3e-94 315.5 0.0 4.1e-94 315.3 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_14 PF13173.6 ORY11228.1 - 0.11 12.5 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain HlyIII PF03006.20 ORY11229.1 - 7.6e-62 208.9 23.1 9.4e-62 208.6 23.1 1.1 1 0 0 1 1 1 1 Haemolysin-III related Orthopox_F14 PF06076.12 ORY11229.1 - 0.069 13.4 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 Orthopoxvirus F14 protein Zn_clus PF00172.18 ORY11230.1 - 0.00011 22.2 7.8 0.00022 21.3 7.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AAA PF00004.29 ORY11231.1 - 1.4e-17 64.3 0.0 2.6e-17 63.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 ORY11231.1 - 0.0043 17.3 0.0 0.011 16.0 0.0 1.7 1 1 1 2 2 2 1 AAA domain Bac_DnaA PF00308.18 ORY11231.1 - 0.011 15.6 0.1 0.044 13.6 0.1 1.8 1 1 1 2 2 2 0 Bacterial dnaA protein T2SSE PF00437.20 ORY11231.1 - 0.018 14.1 0.0 0.032 13.3 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AFG1_ATPase PF03969.16 ORY11231.1 - 0.058 12.3 0.0 0.092 11.6 0.0 1.3 1 0 0 1 1 1 0 AFG1-like ATPase NACHT PF05729.12 ORY11231.1 - 0.1 12.5 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 NACHT domain TrwB_AAD_bind PF10412.9 ORY11231.1 - 0.15 11.0 0.0 0.25 10.2 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_7 PF12775.7 ORY11231.1 - 0.16 11.4 0.0 0.29 10.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 ORY11231.1 - 0.21 11.9 0.0 1.1 9.6 0.0 2.1 2 1 1 3 3 3 0 AAA ATPase domain Aminotran_3 PF00202.21 ORY11232.1 - 2.2e-117 392.2 0.0 2.7e-117 391.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 ORY11232.1 - 0.00017 20.9 0.0 0.0016 17.8 0.0 2.2 2 0 0 2 2 2 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 ORY11232.1 - 0.014 14.6 0.0 0.022 13.9 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II ABC_membrane PF00664.23 ORY11233.1 - 5e-56 190.4 41.6 1.8e-36 126.2 19.4 3.2 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.27 ORY11233.1 - 9.6e-47 158.9 0.2 1.1e-26 93.9 0.0 3.2 3 0 0 3 3 2 2 ABC transporter Zeta_toxin PF06414.12 ORY11233.1 - 8.1e-06 25.3 0.0 0.00086 18.6 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin MMR_HSR1 PF01926.23 ORY11233.1 - 1.2e-05 25.3 1.5 0.1 12.7 0.3 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase SMC_N PF02463.19 ORY11233.1 - 1.4e-05 24.7 1.7 0.53 9.7 0.5 3.8 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 ORY11233.1 - 0.00017 22.0 0.0 0.45 10.9 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 ORY11233.1 - 0.00026 20.9 0.9 1.1 9.0 0.3 3.6 2 1 1 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 ORY11233.1 - 0.00046 19.9 2.0 0.18 11.5 0.2 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 ORY11233.1 - 0.00072 19.5 1.5 0.2 11.6 0.1 2.5 2 0 0 2 2 2 1 RsgA GTPase DUF87 PF01935.17 ORY11233.1 - 0.0019 18.3 4.0 0.042 13.9 0.2 2.7 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_22 PF13401.6 ORY11233.1 - 0.0038 17.5 2.1 2.8 8.2 0.1 3.4 2 1 0 2 2 2 1 AAA domain Roc PF08477.13 ORY11233.1 - 0.015 15.6 1.3 1.6 9.0 0.0 3.1 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase Ploopntkinase3 PF18751.1 ORY11233.1 - 0.021 14.7 0.2 4.2 7.2 0.0 2.5 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 Dynamin_N PF00350.23 ORY11233.1 - 0.036 14.1 0.2 0.036 14.1 0.2 2.8 3 0 0 3 3 2 0 Dynamin family MeaB PF03308.16 ORY11233.1 - 0.046 12.7 2.3 4.3 6.2 0.3 2.5 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_7 PF12775.7 ORY11233.1 - 0.054 13.0 0.6 1.5 8.3 0.1 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_18 PF13238.6 ORY11233.1 - 0.084 13.4 0.6 4.2 7.9 0.0 3.0 3 0 0 3 3 2 0 AAA domain AAA_24 PF13479.6 ORY11233.1 - 0.087 12.5 0.1 2.3 7.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 ORY11233.1 - 0.14 11.9 5.1 5.1 6.8 0.2 2.9 3 0 0 3 3 3 0 AAA domain AAA_28 PF13521.6 ORY11233.1 - 0.27 11.5 1.2 0.75 10.0 0.1 2.3 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.6 ORY11233.1 - 0.98 9.0 3.5 6.9 6.2 0.1 2.8 3 0 0 3 3 3 0 AAA domain DUF4752 PF15944.5 ORY11233.1 - 1 9.4 3.4 3.8 7.6 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4752) ATP_bind_1 PF03029.17 ORY11233.1 - 2.1 8.1 4.9 18 5.0 0.1 2.9 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein Fcf1 PF04900.12 ORY11238.1 - 8e-36 122.4 0.1 1.3e-35 121.7 0.1 1.4 1 0 0 1 1 1 1 Fcf1 PIN_9 PF18477.1 ORY11238.1 - 2.4e-13 50.4 0.2 4.4e-13 49.6 0.0 1.5 2 0 0 2 2 2 1 PIN like domain bZIP_1 PF00170.21 ORY11243.1 - 0.00034 20.6 5.2 0.00064 19.8 5.2 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 ORY11243.1 - 0.00064 19.8 10.5 0.0012 18.8 10.5 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 ORY11243.1 - 0.011 16.3 2.2 0.011 16.3 2.2 2.1 2 0 0 2 2 2 0 bZIP Maf transcription factor CDC45 PF02724.14 ORY11243.1 - 2.1 6.5 8.2 2.6 6.2 8.2 1.1 1 0 0 1 1 1 0 CDC45-like protein ArfGap PF01412.18 ORY11244.1 - 1.6e-37 128.2 0.1 1.6e-37 128.2 0.1 2.6 3 0 0 3 3 3 1 Putative GTPase activating protein for Arf UBA PF00627.31 ORY11244.1 - 0.0052 16.7 0.0 0.013 15.4 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain DnaJ PF00226.31 ORY11245.1 - 3.5e-07 30.3 0.1 2.2e-06 27.7 0.1 2.2 1 1 1 2 2 2 1 DnaJ domain PRA1 PF03208.19 ORY11246.1 - 5.2e-38 129.9 0.9 6.3e-38 129.6 0.9 1.1 1 0 0 1 1 1 1 PRA1 family protein DUF2207 PF09972.9 ORY11246.1 - 0.084 11.6 1.8 0.091 11.5 1.8 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) BRD4_CDT PF17105.5 ORY11247.1 - 7.4 6.3 9.3 23 4.7 9.3 1.8 1 0 0 1 1 1 0 C-terminal domain of bromodomain protein 4 DnaJ PF00226.31 ORY11248.1 - 1.5e-19 69.9 4.7 2.4e-19 69.2 4.7 1.3 1 0 0 1 1 1 1 DnaJ domain Malate_DH PF12434.8 ORY11248.1 - 0.99 9.5 5.4 0.24 11.5 0.6 2.4 2 0 0 2 2 2 0 Malate dehydrogenase enzyme GRP PF07172.11 ORY11249.1 - 0.035 14.8 20.6 0.068 13.9 20.6 1.5 1 0 0 1 1 1 0 Glycine rich protein family AsnC_trans_reg2 PF17805.1 ORY11249.1 - 0.083 13.1 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 AsnC-like ligand binding domain LCCL PF03815.19 ORY11250.1 - 8.2e-18 64.3 0.0 1.3e-17 63.7 0.0 1.3 1 0 0 1 1 1 1 LCCL domain DUF3784 PF12650.7 ORY11250.1 - 0.42 10.8 0.1 0.42 10.8 0.1 2.7 3 1 0 3 3 3 0 Domain of unknown function (DUF3784) DAO PF01266.24 ORY11251.1 - 7.6e-10 38.9 0.5 8.3e-05 22.3 0.0 2.1 1 1 0 2 2 2 2 FAD dependent oxidoreductase Glyco_transf_20 PF00982.21 ORY11253.1 - 1.7e-154 515.0 0.1 2.5e-154 514.5 0.1 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 ORY11253.1 - 5.5e-45 153.3 0.1 1e-44 152.4 0.1 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase Glyco_transf_5 PF08323.11 ORY11253.1 - 0.0062 16.3 0.1 0.013 15.2 0.1 1.5 1 0 0 1 1 1 1 Starch synthase catalytic domain Lipase_3 PF01764.25 ORY11255.1 - 1e-29 103.3 0.0 1.6e-29 102.6 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 ORY11255.1 - 0.0078 16.8 0.9 0.014 16.0 0.8 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORY11255.1 - 0.018 14.3 0.0 0.028 13.7 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DLH PF01738.18 ORY11256.1 - 6.3e-28 97.8 0.0 7.6e-28 97.6 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 ORY11256.1 - 0.028 15.0 0.1 0.037 14.6 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ORY11256.1 - 0.094 12.3 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 ORY11256.1 - 0.13 11.9 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Dynamin_N PF00350.23 ORY11257.1 - 7.3e-11 42.4 0.0 7.3e-10 39.2 0.0 2.7 3 1 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.23 ORY11257.1 - 4e-08 33.3 0.0 0.00017 21.7 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ORY11257.1 - 3.4e-06 27.1 0.4 0.00076 19.4 0.0 3.3 2 1 2 4 4 4 1 RsgA GTPase Roc PF08477.13 ORY11257.1 - 0.0025 18.0 0.0 0.076 13.2 0.0 2.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 ORY11257.1 - 0.0026 18.3 2.2 0.024 15.2 0.0 3.3 3 1 0 3 3 3 1 ABC transporter AAA_22 PF13401.6 ORY11257.1 - 0.0048 17.2 0.0 0.06 13.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 ORY11257.1 - 0.008 16.6 0.0 0.008 16.6 0.0 3.6 4 1 0 4 4 4 1 AAA ATPase domain AIG1 PF04548.16 ORY11257.1 - 0.02 14.2 0.0 0.099 12.0 0.0 2.3 3 0 0 3 3 3 0 AIG1 family PP2C_2 PF13672.6 ORY11257.1 - 0.029 14.0 0.8 0.099 12.3 0.8 1.9 1 0 0 1 1 1 0 Protein phosphatase 2C Septin PF00735.18 ORY11257.1 - 0.034 13.4 0.0 0.15 11.3 0.0 2.0 2 0 0 2 2 2 0 Septin FeoB_N PF02421.18 ORY11257.1 - 0.15 11.6 0.0 6.6 6.2 0.0 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B DUF1492 PF07374.11 ORY11257.1 - 0.6 10.3 3.4 0.96 9.6 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1492) Flocculin_t3 PF13928.6 ORY11259.1 - 1.4 9.5 15.0 4.4 7.9 1.2 3.7 3 0 0 3 3 3 0 Flocculin type 3 repeat AP_endonuc_2 PF01261.24 ORY11260.1 - 5.1e-37 127.4 0.0 6.4e-37 127.0 0.0 1.1 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel DAHP_synth_1 PF00793.20 ORY11261.1 - 2.6e-93 311.9 0.0 3.5e-93 311.4 0.0 1.1 1 0 0 1 1 1 1 DAHP synthetase I family PRCC PF10253.9 ORY11263.1 - 0.42 11.4 4.2 0.54 11.0 4.2 1.2 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting FAA_hydrolase PF01557.18 ORY11264.1 - 5.4e-59 199.5 0.0 7.8e-59 199.0 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Complex1_LYR PF05347.15 ORY11265.1 - 1e-17 63.9 2.9 1.3e-17 63.5 2.9 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 ORY11265.1 - 7.5e-06 26.6 0.5 8.8e-06 26.4 0.5 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.6 ORY11265.1 - 0.032 14.8 3.3 0.19 12.3 0.3 2.0 1 1 1 2 2 2 0 Complex1_LYR-like HSP20 PF00011.21 ORY11266.1 - 9.4e-21 73.9 2.1 3.1e-14 53.0 0.1 2.4 1 1 2 3 3 3 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 ORY11266.1 - 9.1e-07 28.3 0.1 6.1e-06 25.7 0.1 2.1 1 1 0 1 1 1 1 HSP20-like domain found in ArsA Vmethyltransf_C PF08456.10 ORY11266.1 - 0.00093 18.8 0.3 0.0011 18.6 0.3 1.1 1 0 0 1 1 1 1 Viral methyltransferase C-terminal Fungal_trans PF04082.18 ORY11267.1 - 0.019 14.0 0.1 0.036 13.1 0.1 1.4 1 0 0 1 1 1 0 Fungal specific transcription factor domain IFRD PF05004.13 ORY11267.1 - 0.021 13.9 0.1 0.042 13.0 0.1 1.5 1 0 0 1 1 1 0 Interferon-related developmental regulator (IFRD) DUF3387 PF11867.8 ORY11267.1 - 0.047 13.0 0.0 0.084 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3387) Alpha-amylase PF00128.24 ORY11268.1 - 6.2e-115 384.3 1.0 6.8e-115 384.2 0.1 1.4 2 0 0 2 2 2 1 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 ORY11268.1 - 4.8e-07 29.8 0.0 1.5e-06 28.2 0.1 1.9 2 0 0 2 2 2 1 Maltogenic Amylase, C-terminal domain hDGE_amylase PF14701.6 ORY11268.1 - 0.011 14.8 0.0 0.033 13.3 0.0 1.7 2 0 0 2 2 2 0 Glycogen debranching enzyme, glucanotransferase domain Glyco_hydro_114 PF03537.13 ORY11268.1 - 0.081 12.2 1.0 1.2 8.4 0.0 2.5 3 0 0 3 3 3 0 Glycoside-hydrolase family GH114 Sugar_tr PF00083.24 ORY11269.1 - 4.3e-88 296.1 20.6 5e-88 295.9 20.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY11269.1 - 5.1e-18 65.1 26.8 2.4e-09 36.6 15.4 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1421 PF07223.11 ORY11269.1 - 0.19 11.6 0.0 0.38 10.6 0.0 1.4 1 0 0 1 1 1 0 UBA-like domain (DUF1421) Ribosomal_S28e PF01200.18 ORY11270.1 - 3.8e-31 106.9 2.4 4.3e-31 106.7 2.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e HisG PF01634.18 ORY11271.1 - 1.2e-56 191.1 0.0 2.4e-56 190.1 0.0 1.5 2 0 0 2 2 2 1 ATP phosphoribosyltransferase HisG_C PF08029.11 ORY11271.1 - 1.7e-28 98.5 0.3 4e-28 97.4 0.1 1.7 2 0 0 2 2 2 1 HisG, C-terminal domain NMT1 PF09084.11 ORY11271.1 - 0.091 12.7 0.0 0.2 11.6 0.0 1.7 1 1 0 1 1 1 0 NMT1/THI5 like Helo_like_N PF17111.5 ORY11272.1 - 0.015 14.7 0.5 0.096 12.0 0.0 2.3 2 1 1 3 3 3 0 Fungal N-terminal domain of STAND proteins Ank_4 PF13637.6 ORY11272.1 - 0.017 15.7 0.0 3.8 8.2 0.0 2.7 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Vps51 PF08700.11 ORY11272.1 - 0.038 14.1 0.0 0.18 11.9 0.0 2.1 3 0 0 3 3 3 0 Vps51/Vps67 PI3K_P85_iSH2 PF16454.5 ORY11272.1 - 0.05 13.2 1.2 0.068 12.8 0.5 1.5 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Ank_2 PF12796.7 ORY11273.1 - 2.9e-08 34.2 0.0 0.00019 21.9 0.0 2.7 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ORY11273.1 - 0.0063 16.8 0.0 0.31 11.4 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 ORY11273.1 - 0.012 16.2 0.2 0.5 11.0 0.0 3.1 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY11273.1 - 0.018 15.5 0.7 3.7 8.4 0.0 4.2 4 0 0 4 4 4 0 Ankyrin repeat Mob1_phocein PF03637.17 ORY11289.1 - 1.5e-25 90.2 0.6 2.1e-25 89.7 0.6 1.2 1 0 0 1 1 1 1 Mob1/phocein family CxC6 PF18721.1 ORY11289.1 - 0.079 13.2 4.0 0.17 12.2 4.0 1.5 1 0 0 1 1 1 0 CxC6 like cysteine cluster associated with KDZ transposases cobW PF02492.19 ORY11290.1 - 2.2e-45 154.4 0.1 3.3e-45 153.8 0.1 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 ORY11290.1 - 9.2e-07 28.7 0.0 1.6e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain RsgA_GTPase PF03193.16 ORY11290.1 - 0.0002 21.3 0.1 0.26 11.2 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase MeaB PF03308.16 ORY11290.1 - 0.0053 15.8 0.5 0.94 8.4 0.1 2.7 2 1 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 ORY11290.1 - 0.0056 17.0 0.1 0.21 11.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 ORY11290.1 - 0.007 16.8 0.0 0.013 15.9 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain GTP_EFTU PF00009.27 ORY11290.1 - 0.024 14.2 0.8 6.2 6.3 0.1 2.4 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain PND PF17949.1 ORY11290.1 - 0.029 14.6 0.2 0.1 12.8 0.1 1.8 2 0 0 2 2 2 0 FANCM pseudonuclease domain MMR_HSR1 PF01926.23 ORY11290.1 - 0.035 14.2 0.0 0.078 13.1 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase T2SSE PF00437.20 ORY11290.1 - 0.044 12.9 0.1 0.079 12.0 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein ATP_bind_1 PF03029.17 ORY11290.1 - 0.053 13.3 0.1 6.8 6.4 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein TsaE PF02367.17 ORY11290.1 - 0.054 13.5 0.1 0.35 10.9 0.1 2.1 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_23 PF13476.6 ORY11290.1 - 0.056 14.0 0.1 0.13 12.7 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 ORY11290.1 - 0.057 13.1 0.3 0.86 9.3 0.0 2.5 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.6 ORY11290.1 - 0.075 13.6 0.0 0.42 11.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 ORY11290.1 - 0.12 12.3 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Zeta_toxin PF06414.12 ORY11290.1 - 0.13 11.5 0.0 0.36 10.1 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin OrsD PF12013.8 ORY11290.1 - 0.19 12.1 0.0 0.45 11.0 0.0 1.6 1 0 0 1 1 1 0 Orsellinic acid/F9775 biosynthesis cluster protein D AAA_14 PF13173.6 ORY11290.1 - 0.22 11.6 0.6 0.62 10.1 0.1 2.0 3 0 0 3 3 2 0 AAA domain Transferase PF02458.15 ORY11292.1 - 1.3e-13 50.4 0.0 1e-11 44.2 0.0 2.1 2 0 0 2 2 2 2 Transferase family Glyco_hydro_18 PF00704.28 ORY11294.1 - 8.8e-68 229.3 0.0 1e-67 229.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 GspH PF12019.8 ORY11299.1 - 0.09 13.2 0.4 0.22 12.0 0.4 1.6 1 0 0 1 1 1 0 Type II transport protein GspH CHORD PF04968.12 ORY11300.1 - 0.32 11.7 2.9 0.57 10.9 2.9 1.4 1 0 0 1 1 1 0 CHORD zf-C2H2 PF00096.26 ORY11301.1 - 0.0027 18.1 9.3 0.091 13.3 0.5 3.8 3 0 0 3 3 3 2 Zinc finger, C2H2 type RP1-2 PF12042.8 ORY11301.1 - 9.3 6.1 23.0 0.2 11.5 13.0 2.1 2 0 0 2 2 2 0 Tubuliform egg casing silk strands structural domain MFS_1 PF07690.16 ORY11302.1 - 4.1e-19 68.7 30.1 4.1e-19 68.7 30.1 1.8 1 1 0 2 2 2 1 Major Facilitator Superfamily DUF1980 PF09323.10 ORY11302.1 - 0.43 10.5 3.0 5.3 6.9 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) LapA_dom PF06305.11 ORY11302.1 - 2.9 7.8 0.0 2.9 7.8 0.0 4.2 4 0 0 4 4 4 0 Lipopolysaccharide assembly protein A domain MFS_1 PF07690.16 ORY11303.1 - 1.3e-34 119.7 17.3 1.3e-34 119.7 17.3 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY11303.1 - 5e-14 52.0 4.8 5e-14 52.0 4.8 1.9 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_3 PF05977.13 ORY11303.1 - 0.01 14.3 0.7 0.017 13.5 0.7 1.3 1 0 0 1 1 1 0 Transmembrane secretion effector UL41A PF17591.2 ORY11303.1 - 0.012 15.7 0.3 0.17 12.0 0.0 2.8 2 0 0 2 2 2 0 Herpesvirus UL41A Glyco_transf_90 PF05686.12 ORY11304.1 - 1.4e-14 53.8 0.3 8.3e-11 41.4 0.5 3.0 2 1 0 2 2 2 2 Glycosyl transferase family 90 TMEM100 PF16311.5 ORY11304.1 - 0.0069 16.0 2.0 1.8 8.2 0.0 3.0 3 0 0 3 3 3 2 Transmembrane protein 100 DUF4219 PF13961.6 ORY11305.1 - 0.25 11.0 0.1 0.25 11.0 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4219) HET PF06985.11 ORY11308.1 - 5.4e-26 91.7 0.0 9.2e-26 90.9 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) EF-hand_7 PF13499.6 ORY11309.1 - 4.5e-12 46.2 1.0 1.1e-06 29.0 0.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 ORY11309.1 - 1.8e-11 43.0 2.6 0.0004 20.1 0.0 3.6 3 1 0 3 3 3 3 EF-hand domain EF-hand_1 PF00036.32 ORY11309.1 - 1.7e-09 36.5 3.9 0.0017 17.8 0.0 4.2 4 0 0 4 4 4 2 EF hand EF-hand_9 PF14658.6 ORY11309.1 - 8.1e-09 35.7 0.0 0.002 18.4 0.0 2.5 2 1 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 ORY11309.1 - 0.00018 21.3 1.5 0.031 14.1 0.2 3.3 3 1 0 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.6 ORY11309.1 - 0.16 11.5 8.0 2.4 7.8 0.4 3.5 3 1 0 3 3 3 0 EF hand DUF5580 PF17743.1 ORY11309.1 - 0.18 10.3 0.0 0.22 10.0 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5580) HIT PF01230.23 ORY11311.1 - 3.7e-26 91.7 0.4 5e-26 91.3 0.4 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 ORY11311.1 - 0.00035 21.0 0.1 0.00052 20.5 0.1 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Thymidylat_synt PF00303.19 ORY11313.1 - 1.2e-105 352.5 0.0 1.4e-105 352.3 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase HAUS-augmin3 PF14932.6 ORY11314.1 - 0.00074 19.2 10.9 0.00074 19.2 10.9 2.8 1 1 0 2 2 2 1 HAUS augmin-like complex subunit 3 DUF4407 PF14362.6 ORY11314.1 - 0.017 14.5 16.1 0.12 11.7 1.4 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) S6PP_C PF08472.10 ORY11314.1 - 0.054 13.4 0.2 0.18 11.7 0.0 1.9 2 0 0 2 2 2 0 Sucrose-6-phosphate phosphohydrolase C-terminal DUF16 PF01519.16 ORY11314.1 - 0.081 13.4 0.4 0.081 13.4 0.4 3.5 2 1 0 2 2 2 0 Protein of unknown function DUF16 Phage_GPL PF05926.11 ORY11314.1 - 0.11 12.5 3.7 1.5 8.8 0.7 3.1 2 0 0 2 2 2 0 Phage head completion protein (GPL) TssO PF17561.2 ORY11314.1 - 0.11 12.6 0.8 0.49 10.5 0.1 2.5 2 0 0 2 2 2 0 Type VI secretion system, TssO Y_phosphatase3 PF13350.6 ORY11314.1 - 0.16 11.9 3.8 5.2 7.0 0.1 3.3 3 0 0 3 3 3 0 Tyrosine phosphatase family BDV_M PF16520.5 ORY11314.1 - 0.18 12.2 0.1 0.68 10.3 0.0 2.0 2 0 0 2 2 2 0 ssRNA-binding matrix protein of Bornaviridae Baculo_PEP_C PF04513.12 ORY11314.1 - 1.6 8.8 11.3 3.6 7.6 0.7 3.9 2 2 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2115 PF09888.9 ORY11314.1 - 3.1 8.3 9.3 3.4 8.2 0.6 3.1 3 1 0 3 3 2 0 Uncharacterized protein conserved in archaea (DUF2115) DUF1640 PF07798.11 ORY11314.1 - 3.9 7.5 14.6 1.3 9.0 4.4 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1640) Mit_KHE1 PF10173.9 ORY11314.1 - 9.2 6.3 6.9 14 5.7 2.7 2.4 1 1 1 2 2 2 0 Mitochondrial K+-H+ exchange-related Fasciclin PF02469.22 ORY11316.1 - 1.2e-30 106.4 0.2 3.5e-19 69.3 0.0 2.7 2 1 0 2 2 2 2 Fasciclin domain DUF4388 PF14332.6 ORY11316.1 - 0.12 12.7 0.0 0.77 10.1 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4388) CorA PF01544.18 ORY11317.1 - 0.00017 21.0 0.7 0.00028 20.3 0.7 1.5 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Zn_clus PF00172.18 ORY11319.1 - 5.4e-06 26.4 8.2 1.1e-05 25.4 8.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ORY11319.1 - 1.9e-05 23.9 0.1 3.4e-05 23.0 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 ORY11320.1 - 1.9e-43 148.8 44.9 1.9e-43 148.8 44.9 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 ORY11320.1 - 1.6e-12 46.6 10.1 2.6e-12 46.0 10.1 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF5400 PF17379.2 ORY11320.1 - 3.1 8.3 7.3 0.6 10.6 0.2 3.0 3 0 0 3 3 3 0 Family of unknown function (DUF5400) HET PF06985.11 ORY11321.1 - 9.7e-31 107.1 0.9 1.6e-30 106.4 0.2 1.8 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) HET PF06985.11 ORY11322.1 - 1.6e-24 86.9 0.9 5.3e-22 78.7 0.9 2.0 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF815 PF05673.13 ORY11322.1 - 0.033 13.4 0.0 0.046 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Pkinase PF00069.25 ORY11323.1 - 6.7e-33 114.2 0.0 8.1e-33 113.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY11323.1 - 7.9e-22 77.8 0.0 9.5e-22 77.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 ORY11323.1 - 0.012 15.0 0.6 0.037 13.4 0.6 1.7 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2953 PF11167.8 ORY11324.1 - 0.079 13.0 2.4 4.2 7.5 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2953) DUF2418 PF10332.9 ORY11326.1 - 1.4e-34 118.5 0.3 1.4e-34 118.5 0.3 2.2 3 0 0 3 3 3 1 Protein of unknown function (DUF2418) ATG27 PF09451.10 ORY11326.1 - 0.19 11.6 0.2 0.29 11.0 0.2 1.2 1 0 0 1 1 1 0 Autophagy-related protein 27 NADH-u_ox-rdase PF10785.9 ORY11326.1 - 0.25 12.0 1.6 1.2e+02 3.4 0.0 3.3 2 1 1 3 3 3 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit ATP-synt_F PF01990.17 ORY11327.1 - 6.5e-33 112.9 0.1 7.5e-33 112.7 0.1 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit E1_DerP2_DerF2 PF02221.15 ORY11328.1 - 3.5e-30 105.2 0.4 4.4e-30 104.8 0.4 1.1 1 0 0 1 1 1 1 ML domain TRP_N PF14558.6 ORY11328.1 - 0.00053 20.4 0.0 0.00092 19.6 0.0 1.4 1 1 0 1 1 1 1 ML-like domain Big_9 PF17963.1 ORY11328.1 - 0.083 13.6 0.0 0.18 12.6 0.0 1.5 2 0 0 2 2 2 0 Bacterial Ig domain MFMR_assoc PF16596.5 ORY11331.1 - 0.075 13.5 1.5 0.13 12.7 1.5 1.4 1 0 0 1 1 1 0 Disordered region downstream of MFMR FAD_binding_4 PF01565.23 ORY11333.1 - 4.6e-19 68.5 2.9 1.1e-18 67.4 2.9 1.7 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 ORY11333.1 - 6.8e-10 38.9 0.1 1.3e-09 38.0 0.1 1.4 1 0 0 1 1 1 1 Berberine and berberine like Zn_clus PF00172.18 ORY11334.1 - 4.2e-05 23.6 11.0 6.9e-05 22.9 11.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Isochorismatase PF00857.20 ORY11335.1 - 5.9e-33 114.5 0.0 6.9e-33 114.3 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family Choline_transpo PF04515.12 ORY11336.1 - 9.6e-84 281.4 23.8 9.6e-84 281.4 23.8 2.2 2 0 0 2 2 2 1 Plasma-membrane choline transporter DUF4191 PF13829.6 ORY11336.1 - 1.1 8.5 7.3 4.4 6.6 5.5 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) Mannitol_dh_C PF08125.13 ORY11337.1 - 5.9e-46 156.9 0.4 1e-45 156.1 0.4 1.3 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.23 ORY11337.1 - 2.1e-19 70.2 1.0 1.7e-18 67.2 0.1 2.3 2 0 0 2 2 2 1 Mannitol dehydrogenase Rossmann domain 3HCDH_N PF02737.18 ORY11337.1 - 0.0017 18.3 1.3 0.0068 16.3 0.1 2.5 2 1 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 ORY11337.1 - 0.029 14.0 0.9 0.043 13.4 0.2 1.7 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain CaM_bdg_C0 PF10562.9 ORY11337.1 - 0.12 12.4 0.0 0.33 11.0 0.0 1.8 1 0 0 1 1 1 0 Calmodulin-binding domain C0 of NMDA receptor NR1 subunit Glyco_hydro_47 PF01532.20 ORY11340.1 - 2.5e-118 395.9 0.0 3e-118 395.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 BTB PF00651.31 ORY11344.1 - 0.025 14.8 0.0 0.054 13.7 0.0 1.6 1 0 0 1 1 1 0 BTB/POZ domain TRI12 PF06609.13 ORY11345.1 - 2.9e-17 62.3 7.4 4.8e-17 61.6 7.4 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) NAD_binding_2 PF03446.15 ORY11346.1 - 2.6e-33 115.4 0.2 4.1e-33 114.8 0.2 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 ORY11346.1 - 2.9e-10 40.6 0.0 6.8e-10 39.4 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_11 PF14833.6 ORY11346.1 - 1.3e-09 38.4 0.0 3.3e-09 37.0 0.0 1.7 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Shikimate_DH PF01488.20 ORY11346.1 - 3.3e-09 36.9 0.0 8.4e-09 35.6 0.0 1.6 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_N PF03721.14 ORY11346.1 - 3.5e-05 23.4 0.3 0.0001 22.0 0.3 1.7 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_10 PF13460.6 ORY11346.1 - 0.0047 16.9 0.0 0.0085 16.0 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 ORY11346.1 - 0.0088 16.5 0.0 0.025 15.0 0.0 1.8 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain IlvN PF07991.12 ORY11346.1 - 0.0097 15.5 0.0 0.019 14.5 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain GFO_IDH_MocA PF01408.22 ORY11346.1 - 0.03 15.2 0.0 0.06 14.2 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold PDH PF02153.17 ORY11346.1 - 0.043 12.8 0.1 0.065 12.2 0.1 1.2 1 0 0 1 1 1 0 Prephenate dehydrogenase Sacchrp_dh_NADP PF03435.18 ORY11346.1 - 0.044 14.0 0.0 0.12 12.6 0.0 1.7 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 ORY11346.1 - 0.071 13.4 0.3 0.26 11.6 0.3 1.9 1 1 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.18 ORY11346.1 - 0.16 11.8 1.2 4.3 7.2 0.1 2.4 1 1 1 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAT PF04768.13 ORY11347.1 - 3.7e-54 182.9 0.0 1.4e-53 181.0 0.0 1.8 2 0 0 2 2 2 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase SPATA25 PF15218.6 ORY11347.1 - 0.027 14.2 0.0 0.046 13.5 0.0 1.3 1 0 0 1 1 1 0 Spermatogenesis-associated protein 25 Ank_4 PF13637.6 ORY11348.1 - 1.5e-27 95.6 1.7 2.9e-11 43.7 0.1 2.9 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 ORY11348.1 - 1.4e-25 89.0 4.9 3.9e-09 36.6 0.1 4.0 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY11348.1 - 7.8e-25 84.2 0.4 5.5e-06 26.3 0.0 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_2 PF12796.7 ORY11348.1 - 1.6e-24 86.3 1.2 8.2e-13 48.8 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 ORY11348.1 - 2e-23 81.8 4.3 2.9e-06 27.4 0.3 4.1 4 0 0 4 4 4 4 Ankyrin repeat CorA PF01544.18 ORY11349.1 - 0.016 14.6 0.3 0.042 13.2 0.3 1.8 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF4470 PF14737.6 ORY11350.1 - 5.7e-23 80.9 0.1 9.5e-23 80.2 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) COesterase PF00135.28 ORY11351.1 - 2.4e-80 270.8 0.0 3.4e-80 270.4 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 ORY11351.1 - 3.9e-12 46.5 0.2 1.4e-11 44.7 0.2 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 ORY11351.1 - 0.0075 15.8 0.2 0.012 15.1 0.2 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Glyco_hydro_43 PF04616.14 ORY11352.1 - 3e-51 174.5 8.5 3.7e-51 174.2 8.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 CBM_6 PF03422.15 ORY11352.1 - 2.4e-37 128.0 3.4 2.4e-37 128.0 3.4 1.9 2 0 0 2 2 2 1 Carbohydrate binding module (family 6) DUF5010_C PF18099.1 ORY11352.1 - 1.4e-08 34.8 0.7 2.9e-08 33.8 0.7 1.6 1 0 0 1 1 1 1 DUF5010 C-terminal domain Glyco_hydro_32N PF00251.20 ORY11352.1 - 0.0071 15.9 4.0 0.014 15.0 4.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain IBR PF01485.21 ORY11354.1 - 2e-06 27.9 25.8 5.8e-05 23.2 3.0 4.3 4 1 0 4 4 4 2 IBR domain, a half RING-finger domain CUE PF02845.16 ORY11354.1 - 0.07 12.9 0.1 2.8 7.8 0.1 2.4 2 0 0 2 2 2 0 CUE domain zinc_ribbon_9 PF14369.6 ORY11354.1 - 0.072 13.4 0.0 0.072 13.4 0.0 4.1 5 0 0 5 5 5 0 zinc-ribbon NicO PF03824.16 ORY11355.1 - 0.046 13.1 0.1 0.082 12.2 0.1 1.3 1 0 0 1 1 1 0 High-affinity nickel-transport protein Poty_coat PF00767.18 ORY11355.1 - 0.087 12.4 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Potyvirus coat protein CUE PF02845.16 ORY11357.1 - 1.6e-10 40.4 0.0 2.7e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 CUE domain FAD_binding_4 PF01565.23 ORY11359.1 - 3.3e-26 91.7 4.5 5.6e-26 90.9 4.5 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 ORY11359.1 - 4.3e-05 23.5 0.0 7.9e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like Pkinase PF00069.25 ORY11388.1 - 1.3e-68 231.2 0.0 2e-68 230.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY11388.1 - 7.9e-50 169.5 0.0 1.3e-49 168.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORY11388.1 - 0.00039 19.3 0.0 0.00062 18.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 ORY11388.1 - 0.014 14.7 0.0 0.17 11.2 0.0 2.2 2 0 0 2 2 2 0 Kinase-like Seadorna_VP7 PF07387.11 ORY11388.1 - 0.19 10.8 0.1 0.29 10.2 0.1 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Eisosome1 PF12757.7 ORY11390.1 - 1.1e-37 129.0 15.4 1.1e-37 129.0 15.4 3.6 2 1 1 3 3 3 1 Eisosome protein 1 Y_phosphatase3 PF13350.6 ORY11391.1 - 2.7e-38 132.2 0.5 4.9e-38 131.4 0.5 1.3 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 ORY11391.1 - 2.6e-09 36.9 0.0 6.5e-08 32.3 0.0 2.3 2 0 0 2 2 2 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 ORY11391.1 - 0.00081 19.0 0.0 0.0014 18.2 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 ORY11391.1 - 0.0025 17.6 0.1 0.015 15.1 0.0 2.0 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Myotub-related PF06602.14 ORY11391.1 - 0.0046 15.9 0.3 0.0084 15.1 0.1 1.5 2 0 0 2 2 2 1 Myotubularin-like phosphatase domain OpuAC PF04069.12 ORY11391.1 - 0.078 12.5 0.1 2.6 7.5 0.0 2.1 2 0 0 2 2 2 0 Substrate binding domain of ABC-type glycine betaine transport system CMAS PF02353.20 ORY11392.1 - 3e-62 210.4 0.1 3.7e-62 210.1 0.1 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.12 ORY11392.1 - 1.1e-10 42.0 0.0 2.6e-10 40.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY11392.1 - 1.5e-09 38.4 0.0 3.2e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY11392.1 - 7.4e-09 35.6 0.0 1.2e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY11392.1 - 0.00083 20.1 0.0 0.0017 19.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY11392.1 - 0.003 17.4 0.0 0.0052 16.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 ORY11392.1 - 0.026 14.3 0.0 0.039 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 ORY11392.1 - 0.07 12.7 0.1 0.12 11.9 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase small domain PMM PF03332.13 ORY11393.1 - 1.5e-98 328.9 0.0 1.8e-98 328.7 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase DUF2608 PF11019.8 ORY11393.1 - 0.1 12.1 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2608) S6PP PF05116.13 ORY11393.1 - 0.2 11.1 0.0 2.6 7.5 0.0 2.0 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase SEP PF08059.13 ORY11394.1 - 5.8e-14 52.4 0.0 1.1e-13 51.5 0.0 1.5 1 0 0 1 1 1 1 SEP domain zf-RanBP PF00641.18 ORY11395.1 - 0.00015 21.0 2.6 0.00031 20.0 2.6 1.5 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others TRADD_N PF09034.10 ORY11395.1 - 0.1 12.6 0.1 34 4.5 0.0 3.2 3 1 1 4 4 4 0 TRADD, N-terminal domain Vitellogenin_N PF01347.22 ORY11395.1 - 0.14 10.5 0.0 0.2 10.0 0.0 1.1 1 0 0 1 1 1 0 Lipoprotein amino terminal region HOOK PF05622.12 ORY11395.1 - 0.3 9.2 0.1 0.38 8.8 0.1 1.1 1 0 0 1 1 1 0 HOOK protein Fmp27_WPPW PF10359.9 ORY11397.1 - 0.01 14.7 3.4 0.011 14.6 3.4 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain TFIIF_alpha PF05793.12 ORY11397.1 - 0.034 12.8 10.0 0.04 12.5 10.0 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) GAS PF13851.6 ORY11397.1 - 0.042 13.2 10.7 0.052 12.9 10.7 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding CENP-O PF09496.10 ORY11397.1 - 0.059 13.3 2.0 0.07 13.1 2.0 1.1 1 0 0 1 1 1 0 Cenp-O kinetochore centromere component RNA_pol_3_Rpc31 PF11705.8 ORY11397.1 - 0.087 13.1 12.3 0.1 12.8 12.3 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Cwf_Cwc_15 PF04889.12 ORY11397.1 - 0.11 12.2 9.5 0.15 11.8 9.5 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CorA PF01544.18 ORY11397.1 - 0.43 9.8 3.0 0.43 9.9 3.0 1.0 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein NOA36 PF06524.12 ORY11397.1 - 1.3 8.3 6.2 1.7 7.9 6.2 1.2 1 0 0 1 1 1 0 NOA36 protein Dicty_REP PF05086.12 ORY11397.1 - 1.9 6.4 7.8 2.2 6.1 7.8 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Glyco_hydro_7 PF00840.20 ORY11399.1 - 7.7e-207 687.2 16.4 9.6e-207 686.9 16.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 CBM_1 PF00734.18 ORY11399.1 - 1.4e-13 50.6 8.7 1.4e-13 50.6 8.7 5.0 5 1 0 5 5 5 1 Fungal cellulose binding domain Fungal_trans_2 PF11951.8 ORY11400.1 - 9.1e-60 202.5 0.0 1.3e-59 201.9 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY11400.1 - 1.2e-08 34.9 9.0 2.4e-08 33.9 9.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pam17 PF08566.10 ORY11401.1 - 6e-62 208.3 0.1 8.3e-62 207.9 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 TarH PF02203.15 ORY11401.1 - 0.078 12.9 0.3 0.12 12.3 0.3 1.3 1 0 0 1 1 1 0 Tar ligand binding domain homologue GerD PF17898.1 ORY11405.1 - 0.043 13.8 3.9 0.71 9.8 0.3 3.8 4 0 0 4 4 4 0 Spore germination GerD central core domain NCA2 PF08637.10 ORY11405.1 - 0.12 11.6 2.6 0.081 12.1 0.9 1.5 2 0 0 2 2 2 0 ATP synthase regulation protein NCA2 OmpH PF03938.14 ORY11405.1 - 8.1 6.8 17.0 4 7.8 8.3 3.3 3 1 1 4 4 4 0 Outer membrane protein (OmpH-like) ORC6 PF05460.13 ORY11406.1 - 0.51 9.5 2.6 0.73 9.0 2.6 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Pyr_redox_2 PF07992.14 ORY11409.1 - 3.3e-10 39.7 0.0 1.5e-09 37.5 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORY11409.1 - 6.4e-10 39.1 1.4 2e-07 31.1 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 ORY11409.1 - 6.9e-10 38.7 0.8 5.6e-08 32.4 0.8 3.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 ORY11409.1 - 2.6e-08 32.8 0.0 6.1e-08 31.5 0.0 1.6 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_9 PF13454.6 ORY11409.1 - 2.4e-07 30.8 0.3 8e-07 29.2 0.0 1.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding Amino_oxidase PF01593.24 ORY11409.1 - 1.5e-05 24.5 0.0 3.2e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Thi4 PF01946.17 ORY11409.1 - 3.4e-05 23.2 1.7 0.00017 20.9 0.2 2.2 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 ORY11409.1 - 7.3e-05 22.5 0.5 0.015 14.9 0.0 2.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 ORY11409.1 - 7.6e-05 23.2 2.4 0.16 12.5 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 ORY11409.1 - 0.00011 21.6 1.1 0.019 14.3 0.2 2.2 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 ORY11409.1 - 0.0012 18.3 1.5 0.5 9.6 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.14 ORY11409.1 - 0.0017 17.2 4.8 0.0032 16.2 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 ORY11409.1 - 0.0022 17.2 5.1 0.041 12.9 0.1 2.3 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 ORY11409.1 - 0.0035 16.5 1.0 0.0059 15.7 0.1 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein K_oxygenase PF13434.6 ORY11409.1 - 0.0056 15.9 0.4 0.023 13.9 0.1 2.1 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.22 ORY11409.1 - 0.0095 15.1 6.1 0.12 11.5 2.1 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_3 PF01494.19 ORY11409.1 - 0.028 13.7 0.2 0.028 13.7 0.2 1.7 2 0 0 2 2 2 0 FAD binding domain Trp_halogenase PF04820.14 ORY11409.1 - 0.088 11.6 5.3 0.53 9.1 0.1 2.5 3 0 0 3 3 3 0 Tryptophan halogenase Complex1_LYR PF05347.15 ORY11410.1 - 5.6e-16 58.3 0.0 7.7e-16 57.9 0.0 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 ORY11410.1 - 0.0019 18.9 0.0 0.0059 17.3 0.0 1.7 1 1 1 2 2 2 1 Complex1_LYR-like Acetyltransf_1 PF00583.25 ORY11411.1 - 7e-14 52.1 0.0 8e-14 51.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ORY11411.1 - 3.1e-07 30.7 0.0 3.9e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ORY11411.1 - 1.3e-06 28.2 0.0 2.3e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 ORY11411.1 - 3.8e-06 26.9 0.0 4.8e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Inhibitor_I53 PF11714.8 ORY11413.1 - 0.062 13.5 0.4 0.098 12.9 0.4 1.3 1 0 0 1 1 1 0 Thrombin inhibitor Madanin ABC_tran PF00005.27 ORY11414.1 - 4.2e-49 166.6 0.8 2.9e-26 92.6 0.0 2.7 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 ORY11414.1 - 2.6e-23 83.3 3.5 1.8e-05 24.7 0.0 4.3 3 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 ORY11414.1 - 3.8e-15 55.8 51.2 6.3e-09 35.4 10.4 3.1 4 0 0 4 4 4 2 ABC-2 family transporter protein SMC_N PF02463.19 ORY11414.1 - 2.7e-08 33.5 4.2 0.03 13.8 0.0 3.8 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 ORY11414.1 - 8.9e-07 28.6 1.7 0.0027 17.4 0.2 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 ORY11414.1 - 1.7e-06 28.7 4.1 0.028 14.9 0.3 2.4 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 ORY11414.1 - 2.8e-06 27.3 0.0 0.019 14.7 0.3 3.2 3 0 0 3 3 3 1 AAA ATPase domain RsgA_GTPase PF03193.16 ORY11414.1 - 1.1e-05 25.4 0.3 0.063 13.2 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_27 PF13514.6 ORY11414.1 - 0.00025 20.7 0.5 0.084 12.5 0.1 2.3 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 ORY11414.1 - 0.00074 19.9 0.3 1.7 9.0 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_30 PF13604.6 ORY11414.1 - 0.00081 19.2 0.9 1.4 8.6 0.2 2.7 2 0 0 2 2 2 2 AAA domain DUF4162 PF13732.6 ORY11414.1 - 0.02 15.6 0.0 6.7 7.5 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4162) AAA_22 PF13401.6 ORY11414.1 - 0.031 14.6 0.4 2 8.7 0.1 3.1 3 0 0 3 3 2 0 AAA domain Zeta_toxin PF06414.12 ORY11414.1 - 0.033 13.5 0.9 5.2 6.3 0.1 2.4 2 0 0 2 2 2 0 Zeta toxin RNA_helicase PF00910.22 ORY11414.1 - 0.14 12.6 0.1 2.6 8.5 0.0 2.3 2 0 0 2 2 2 0 RNA helicase AAA_28 PF13521.6 ORY11414.1 - 0.17 12.2 1.2 2.7 8.2 0.6 2.4 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 ORY11414.1 - 0.21 11.9 0.4 4.9 7.5 0.1 2.7 2 0 0 2 2 2 0 AAA domain RELT PF12606.8 ORY11414.1 - 0.32 10.0 2.1 1.2 8.2 2.1 1.9 1 0 0 1 1 1 0 Tumour necrosis factor receptor superfamily member 19 Ribosomal_60s PF00428.19 ORY11416.1 - 2.1e-09 37.8 0.2 2.9e-09 37.4 0.2 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein Glyco_transf_21 PF13506.6 ORY11416.1 - 0.054 13.0 0.0 0.057 12.9 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 21 Glyco_hydro_6 PF01341.17 ORY11417.1 - 1.4e-55 189.2 0.2 1.8e-55 188.9 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 Glyco_hydro_43 PF04616.14 ORY11419.1 - 4.5e-17 62.3 2.5 7e-17 61.7 2.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 CBM_35 PF16990.5 ORY11419.1 - 5.7e-08 33.0 0.1 1.4e-07 31.8 0.0 1.7 2 0 0 2 2 2 1 Carbohydrate binding module (family 35) Col_cuticle_N PF01484.17 ORY11423.1 - 0.0073 16.3 0.2 0.014 15.5 0.2 1.4 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain DUF4234 PF14018.6 ORY11423.1 - 0.63 10.2 6.2 1 9.6 6.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4234) Phage_lysozyme PF00959.19 ORY11425.1 - 4.8e-14 52.7 0.0 6.4e-14 52.3 0.0 1.2 1 0 0 1 1 1 1 Phage lysozyme MFS_1 PF07690.16 ORY11426.1 - 7.4e-34 117.2 34.9 7.4e-34 117.2 34.9 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 ORY11426.1 - 0.00017 21.0 3.8 0.00017 21.0 3.8 2.6 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB DUF1129 PF06570.11 ORY11426.1 - 1.6 8.1 0.0 1.6 8.1 0.0 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1129) Cutinase PF01083.22 ORY11428.1 - 9.4e-46 156.0 1.1 1.1e-45 155.8 1.1 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 ORY11428.1 - 0.066 12.8 0.2 0.089 12.3 0.2 1.2 1 0 0 1 1 1 0 PE-PPE domain Abhydrolase_1 PF00561.20 ORY11428.1 - 0.11 12.2 0.1 0.14 11.8 0.1 1.1 1 0 0 1 1 1 0 alpha/beta hydrolase fold Acetyltransf_10 PF13673.7 ORY11429.1 - 1.3e-05 25.1 0.0 1.8e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORY11429.1 - 1.7e-05 25.0 0.0 2.7e-05 24.4 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ORY11429.1 - 3.1e-05 24.3 0.1 4.8e-05 23.7 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF4381 PF14316.6 ORY11430.1 - 0.0012 19.1 0.0 0.0022 18.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4381) PepSY_TM_like_2 PF16357.5 ORY11430.1 - 0.034 14.1 0.1 0.049 13.6 0.1 1.3 1 0 0 1 1 1 0 Putative PepSY_TM-like Hum_adeno_E3A PF05393.11 ORY11430.1 - 0.081 12.9 0.3 0.19 11.8 0.3 1.5 1 0 0 1 1 1 0 Human adenovirus early E3A glycoprotein TMEM154 PF15102.6 ORY11430.1 - 0.1 12.5 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family DUF3357 PF11837.8 ORY11430.1 - 0.37 11.3 3.1 7.5 7.1 1.7 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF3357) Acetyltransf_1 PF00583.25 ORY11431.1 - 2.8e-09 37.2 0.0 7.5e-09 35.8 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ORY11431.1 - 2e-08 34.2 0.0 4.6e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ORY11431.1 - 1.6e-06 28.4 0.1 3.9e-06 27.2 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 ORY11431.1 - 3.3e-05 24.0 0.2 0.00043 20.4 0.0 2.2 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 ORY11431.1 - 5.9e-05 23.1 0.0 0.00011 22.3 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 ORY11431.1 - 0.003 17.5 0.0 0.0067 16.4 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_15 PF17013.5 ORY11431.1 - 0.038 13.4 0.0 0.24 10.8 0.0 1.9 1 1 0 1 1 1 0 Putative acetyl-transferase AA_permease_2 PF13520.6 ORY11433.1 - 1.5e-58 198.6 45.0 1.8e-58 198.4 45.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ORY11433.1 - 5.5e-29 101.1 33.1 7.5e-29 100.6 33.1 1.0 1 0 0 1 1 1 1 Amino acid permease DUF829 PF05705.14 ORY11434.1 - 6.3e-05 23.0 0.0 9.1e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Zn_clus PF00172.18 ORY11435.1 - 5e-06 26.5 8.6 5e-06 26.5 8.6 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ORY11435.1 - 6.1e-05 22.2 0.1 0.00012 21.2 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain CoA_transf_3 PF02515.17 ORY11436.1 - 2e-42 145.7 0.0 2.7e-38 132.0 0.0 2.2 2 0 0 2 2 2 2 CoA-transferase family III NmrA PF05368.13 ORY11437.1 - 1.1e-09 38.2 0.0 1.8e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family HTH_psq PF05225.16 ORY11438.1 - 0.0036 17.0 0.1 0.0058 16.4 0.1 1.6 1 1 0 1 1 1 1 helix-turn-helix, Psq domain HTH_23 PF13384.6 ORY11438.1 - 0.015 15.1 0.2 0.021 14.6 0.2 1.5 1 1 0 1 1 1 0 Homeodomain-like domain HTH_30 PF13556.6 ORY11438.1 - 0.05 13.4 0.0 0.083 12.7 0.0 1.3 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain HTH_28 PF13518.6 ORY11438.1 - 0.062 13.4 0.1 0.09 12.9 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain COG4 PF08318.12 ORY11440.1 - 0.021 13.9 0.0 0.025 13.7 0.0 1.2 1 0 0 1 1 1 0 COG4 transport protein AA_permease_2 PF13520.6 ORY11441.1 - 2.7e-63 214.3 51.5 3.5e-63 213.9 51.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ORY11441.1 - 1.2e-19 70.3 45.4 1.7e-19 69.8 45.4 1.1 1 0 0 1 1 1 1 Amino acid permease SET PF00856.28 ORY11442.1 - 1.2e-11 45.3 0.0 3.2e-11 43.9 0.0 1.8 1 1 0 1 1 1 1 SET domain Glyco_hydro_10 PF00331.20 ORY11443.1 - 2.9e-102 342.0 0.2 3.7e-102 341.7 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_1 PF00734.18 ORY11443.1 - 2.3e-11 43.4 10.9 2.3e-11 43.4 10.9 2.6 2 0 0 2 2 2 1 Fungal cellulose binding domain 7tm_6 PF02949.20 ORY11445.1 - 0.11 11.6 0.0 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 7tm Odorant receptor Ferric_reduct PF01794.19 ORY11447.1 - 9.1e-13 48.4 12.4 2e-12 47.3 9.7 2.3 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 ORY11447.1 - 5.4e-08 32.9 0.0 0.0034 17.5 0.1 2.5 2 0 0 2 2 2 2 FAD-binding domain NAD_binding_6 PF08030.12 ORY11447.1 - 3.9e-07 30.3 0.0 9.1e-07 29.1 0.0 1.6 1 1 0 1 1 1 1 Ferric reductase NAD binding domain DUF309 PF03745.14 ORY11448.1 - 0.067 12.9 0.1 10 5.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF309) Mitofilin PF09731.9 ORY11449.1 - 2.5 6.8 12.0 4 6.2 12.0 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein SPATA3 PF15662.5 ORY11449.1 - 3.1 8.4 10.3 10 6.7 10.3 1.9 1 0 0 1 1 1 0 Spermatogenesis-associated protein 3 family CFEM PF05730.11 ORY11451.1 - 4.3e-13 49.1 10.8 5.6e-13 48.8 10.8 1.1 1 0 0 1 1 1 1 CFEM domain TIL PF01826.17 ORY11451.1 - 0.1 12.9 7.5 0.13 12.5 7.0 1.4 1 1 0 1 1 1 0 Trypsin Inhibitor like cysteine rich domain LRR_4 PF12799.7 ORY11452.1 - 0.11 13.0 2.7 2e+02 2.6 0.0 5.8 6 2 0 6 6 6 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY11454.1 - 2.9e-05 23.7 3.5 2.9e-05 23.7 3.5 2.2 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 ORY11454.1 - 4.7e-05 23.7 5.0 4.7e-05 23.7 5.0 2.7 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) DUF3533 PF12051.8 ORY11455.1 - 2.7e-117 391.9 10.8 3.3e-117 391.6 10.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) DUF1746 PF08508.10 ORY11455.1 - 0.15 12.4 1.9 0.9 9.9 0.7 2.4 2 0 0 2 2 2 0 Fungal domain of unknown function (DUF1746) Sugar_tr PF00083.24 ORY11457.1 - 3.7e-43 148.0 13.6 2.1e-30 106.0 0.9 2.4 3 0 0 3 3 3 2 Sugar (and other) transporter MFS_1 PF07690.16 ORY11457.1 - 4.3e-25 88.4 12.2 9e-24 84.0 13.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 ORY11457.1 - 0.49 8.9 18.0 0.014 14.0 3.6 3.4 2 2 1 3 3 3 0 MFS/sugar transport protein DUF4231 PF14015.6 ORY11457.1 - 0.92 10.0 2.6 1.5 9.3 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) FixQ PF05545.11 ORY11457.1 - 2.9 7.9 4.6 74 3.4 0.0 2.8 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ FA_desaturase PF00487.24 ORY11457.1 - 8.6 6.1 7.0 6.3 6.6 1.3 3.1 3 0 0 3 3 3 0 Fatty acid desaturase Ecl1 PF12855.7 ORY11458.1 - 7.6 7.7 18.3 0.7 11.0 9.3 2.4 2 0 0 2 2 2 0 ECL1/2/3 zinc binding proteins p450 PF00067.22 ORY11459.1 - 1.3e-24 86.8 0.0 2e-24 86.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 bZIP_1 PF00170.21 ORY11480.1 - 9.4e-05 22.4 11.6 0.64 10.1 0.2 4.4 4 0 0 4 4 4 2 bZIP transcription factor DUF1192 PF06698.11 ORY11480.1 - 0.015 15.4 3.2 1.5 8.9 0.0 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) DivIC PF04977.15 ORY11480.1 - 0.039 13.7 18.5 0.21 11.4 1.6 4.8 4 1 1 5 5 5 0 Septum formation initiator bZIP_2 PF07716.15 ORY11480.1 - 0.04 14.0 22.9 0.049 13.7 1.2 4.5 5 0 0 5 5 4 0 Basic region leucine zipper CCDC144C PF14915.6 ORY11480.1 - 0.04 13.0 12.7 0.12 11.4 1.9 2.8 2 1 0 2 2 2 0 CCDC144C protein coiled-coil region SPT16 PF08644.11 ORY11480.1 - 0.1 12.8 2.6 0.95 9.6 0.1 2.5 2 0 0 2 2 2 0 FACT complex subunit (SPT16/CDC68) PKcGMP_CC PF16808.5 ORY11480.1 - 0.11 12.4 0.0 0.11 12.4 0.0 4.4 4 0 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF4407 PF14362.6 ORY11480.1 - 0.29 10.5 11.6 2.3 7.5 2.8 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) CALCOCO1 PF07888.11 ORY11480.1 - 0.3 9.9 23.3 0.014 14.3 10.3 3.3 1 1 2 3 3 3 0 Calcium binding and coiled-coil domain (CALCOCO1) like CENP-F_leu_zip PF10473.9 ORY11480.1 - 0.34 10.9 20.3 0.58 10.2 3.4 3.4 2 1 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TPR_MLP1_2 PF07926.12 ORY11480.1 - 1.8 8.7 20.2 3.8 7.6 0.7 4.1 4 1 0 4 4 4 0 TPR/MLP1/MLP2-like protein TMF_DNA_bd PF12329.8 ORY11480.1 - 2.1 8.4 18.0 0.88 9.6 0.1 4.7 5 0 0 5 5 5 0 TATA element modulatory factor 1 DNA binding OmpH PF03938.14 ORY11480.1 - 2.2 8.6 12.6 1.7 9.0 0.7 3.6 3 1 1 4 4 4 0 Outer membrane protein (OmpH-like) BLOC1_2 PF10046.9 ORY11480.1 - 3.2 8.1 8.5 1.6 9.1 0.2 3.7 3 2 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4140 PF13600.6 ORY11480.1 - 5.2 7.6 17.8 9.5 6.7 0.1 4.6 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) DUF641 PF04859.12 ORY11480.1 - 5.6 7.3 11.8 1.6 9.1 0.1 3.5 3 1 0 3 3 3 0 Plant protein of unknown function (DUF641) GAS PF13851.6 ORY11480.1 - 8.3 5.7 23.4 0.39 10.0 1.1 3.6 2 2 2 4 4 4 0 Growth-arrest specific micro-tubule binding ADIP PF11559.8 ORY11480.1 - 9.6 6.3 18.3 0.72 9.9 3.0 3.5 3 1 0 3 3 3 0 Afadin- and alpha -actinin-Binding ProQ PF04352.13 ORY11481.1 - 0.0037 17.1 1.4 2 8.4 0.0 3.5 4 0 0 4 4 4 2 ProQ/FINO family ATP-grasp_2 PF08442.10 ORY11481.1 - 0.035 13.7 0.0 0.059 12.9 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain TMCO5 PF14992.6 ORY11482.1 - 0.026 14.1 3.9 0.034 13.7 3.9 1.1 1 0 0 1 1 1 0 TMCO5 family SufE PF02657.15 ORY11482.1 - 0.11 12.4 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 Fe-S metabolism associated domain p450 PF00067.22 ORY11484.1 - 2.3e-51 175.0 0.0 3.1e-51 174.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF4148 PF13663.6 ORY11486.1 - 0.18 12.0 1.8 0.32 11.2 1.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) HlyIII PF03006.20 ORY11487.1 - 6.2e-38 130.7 9.8 7.4e-38 130.5 9.8 1.0 1 0 0 1 1 1 1 Haemolysin-III related His_Phos_2 PF00328.22 ORY11488.1 - 2.5e-30 106.1 0.0 3.1e-30 105.8 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Glyco_hydro_61 PF03443.14 ORY11490.1 - 1.6e-62 211.1 0.7 2.1e-62 210.7 0.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 NPCBM_assoc PF10633.9 ORY11490.1 - 0.0076 16.5 1.0 0.18 12.1 0.0 3.0 3 0 0 3 3 3 1 NPCBM-associated, NEW3 domain of alpha-galactosidase HSP90 PF00183.18 ORY11492.1 - 7.5e-221 734.5 31.8 9.4e-221 734.2 31.8 1.0 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 ORY11492.1 - 1.5e-15 57.7 0.2 2.7e-15 56.8 0.2 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 ORY11492.1 - 1.3e-10 41.2 0.2 4.2e-10 39.6 0.2 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Glyco_hydro_88 PF07470.13 ORY11493.1 - 6.6e-87 291.8 0.0 7.6e-87 291.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Glyco_hydro_76 PF03663.14 ORY11493.1 - 0.16 11.4 3.3 1.5 8.2 2.3 2.6 1 1 2 3 3 3 0 Glycosyl hydrolase family 76 MFS_1 PF07690.16 ORY11494.1 - 3.5e-31 108.4 19.2 4.6e-31 108.0 19.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily TM140 PF14985.6 ORY11494.1 - 0.018 14.6 1.2 0.018 14.6 1.2 2.1 2 0 0 2 2 2 0 TM140 protein family DUF2970 PF11174.8 ORY11494.1 - 0.29 11.0 3.3 0.46 10.4 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2970) F-box-like PF12937.7 ORY11495.1 - 4.6e-06 26.4 2.9 5.4e-06 26.2 0.9 2.1 2 0 0 2 2 2 1 F-box-like LRR_8 PF13855.6 ORY11495.1 - 0.00024 20.8 0.9 0.028 14.2 0.3 2.5 2 0 0 2 2 2 2 Leucine rich repeat F-box PF00646.33 ORY11495.1 - 0.00073 19.3 2.0 0.00073 19.3 2.0 1.9 2 0 0 2 2 2 1 F-box domain F-box_4 PF15966.5 ORY11495.1 - 0.0046 16.8 0.6 0.012 15.4 0.2 2.0 2 0 0 2 2 2 1 F-box Zn_clus PF00172.18 ORY11496.1 - 8.9e-10 38.5 8.0 1.4e-09 37.9 8.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ORY11496.1 - 0.00053 19.1 0.4 0.00053 19.1 0.4 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Cytochrom_B561 PF03188.16 ORY11498.1 - 7e-06 26.2 6.5 1.6e-05 25.1 6.5 1.6 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF998 PF06197.13 ORY11498.1 - 0.16 11.6 19.4 0.23 11.1 6.3 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF998) DUF4079 PF13301.6 ORY11498.1 - 1.4 9.0 12.7 9.9 6.3 3.0 3.7 2 1 1 3 3 3 0 Protein of unknown function (DUF4079) DUF2427 PF10348.9 ORY11498.1 - 5.8 6.7 7.3 1.6 8.6 3.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF2427) DUF4131 PF13567.6 ORY11498.1 - 6 6.5 13.2 3.7 7.2 1.3 3.4 3 1 1 4 4 4 0 Domain of unknown function (DUF4131) Spc7 PF08317.11 ORY11499.1 - 5.1e-06 25.6 14.5 0.00064 18.7 0.5 2.2 2 0 0 2 2 2 2 Spc7 kinetochore protein ABC_tran_CTD PF16326.5 ORY11499.1 - 0.0011 19.1 24.1 0.0022 18.2 5.1 4.0 3 1 0 3 3 3 2 ABC transporter C-terminal domain DUF4407 PF14362.6 ORY11499.1 - 0.0018 17.7 10.2 0.0018 17.7 10.2 1.6 1 1 1 2 2 2 2 Domain of unknown function (DUF4407) AAA_13 PF13166.6 ORY11499.1 - 0.008 14.9 6.9 0.01 14.5 6.9 1.2 1 0 0 1 1 1 1 AAA domain Fez1 PF06818.15 ORY11499.1 - 0.012 16.1 10.9 0.012 16.1 10.9 2.7 1 1 2 3 3 3 0 Fez1 BLOC1_2 PF10046.9 ORY11499.1 - 0.019 15.2 8.6 0.019 15.2 3.5 2.6 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 COG5 PF10392.9 ORY11499.1 - 0.022 14.9 5.2 0.054 13.7 1.0 2.6 2 0 0 2 2 2 0 Golgi transport complex subunit 5 FapA PF03961.13 ORY11499.1 - 0.022 13.4 0.4 0.022 13.4 0.4 2.2 1 1 1 2 2 2 0 Flagellar Assembly Protein A Baculo_PEP_C PF04513.12 ORY11499.1 - 0.045 13.8 1.0 0.26 11.3 1.0 2.1 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Kre28 PF17097.5 ORY11499.1 - 0.068 12.1 9.1 0.14 11.1 9.1 1.6 1 1 0 1 1 1 0 Spindle pole body component DUF1664 PF07889.12 ORY11499.1 - 0.15 12.1 1.2 3.2 7.8 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.11 ORY11499.1 - 0.19 12.2 4.9 14 6.1 0.0 3.4 2 1 2 4 4 4 0 Flagella accessory protein C (FlaC) GAS PF13851.6 ORY11499.1 - 0.37 10.1 23.4 0.14 11.5 9.4 2.5 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding Atg14 PF10186.9 ORY11499.1 - 0.69 8.9 14.9 1.9 7.5 6.4 2.3 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Laminin_II PF06009.12 ORY11499.1 - 0.7 9.9 9.6 4.9 7.2 0.4 2.4 2 0 0 2 2 2 0 Laminin Domain II Allexi_40kDa PF05549.11 ORY11499.1 - 0.88 9.0 3.6 0.57 9.6 1.1 2.0 1 1 1 2 2 2 0 Allexivirus 40kDa protein DUF641 PF04859.12 ORY11499.1 - 0.91 9.9 16.3 6.7 7.1 4.3 3.2 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) Med30 PF11315.8 ORY11499.1 - 1.1 9.5 6.5 0.57 10.4 1.6 2.2 1 1 1 2 2 2 0 Mediator complex subunit 30 DUF3552 PF12072.8 ORY11499.1 - 1.2 8.5 19.8 3.1 7.2 8.9 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) HIP1_clath_bdg PF16515.5 ORY11499.1 - 1.8 9.2 20.4 1.4 9.5 6.3 2.9 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 GvpK PF05121.12 ORY11499.1 - 6.1 7.0 16.9 0.22 11.6 4.6 3.1 1 1 2 3 3 3 0 Gas vesicle protein K UPF0242 PF06785.11 ORY11499.1 - 7.4 6.6 22.7 2.5 8.2 2.7 2.6 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus Arm-DNA-bind_5 PF17293.2 ORY11499.1 - 7.8 7.0 9.0 6.5 7.3 2.7 3.0 2 1 1 3 3 3 0 Arm DNA-binding domain DivIC PF04977.15 ORY11499.1 - 8.2 6.3 23.5 0.37 10.6 0.8 3.6 2 1 1 3 3 3 0 Septum formation initiator Cob_adeno_trans PF01923.18 ORY11499.1 - 8.3 6.5 11.5 2.7 8.1 1.4 2.9 2 1 1 3 3 3 0 Cobalamin adenosyltransferase CEP63 PF17045.5 ORY11499.1 - 8.5 6.2 24.3 2.9 7.7 2.8 2.8 2 1 0 3 3 3 0 Centrosomal protein of 63 kDa Syntaxin-6_N PF09177.11 ORY11499.1 - 9.8 6.8 13.9 16 6.1 1.8 3.6 1 1 2 3 3 3 0 Syntaxin 6, N-terminal MgtC PF02308.16 ORY11501.1 - 0.014 15.7 2.9 0.014 15.7 2.9 2.0 2 0 0 2 2 2 0 MgtC family DUF3040 PF11239.8 ORY11501.1 - 2.2 8.6 5.9 18 5.7 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) PhaG_MnhG_YufB PF03334.14 ORY11501.1 - 2.6 8.4 8.2 15 5.9 4.2 3.0 2 0 0 2 2 2 0 Na+/H+ antiporter subunit Herpes_gE PF02480.16 ORY11502.1 - 0.039 12.7 0.0 0.07 11.9 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Orthoreo_P10 PF07204.11 ORY11502.1 - 0.091 12.7 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 Abhydrolase_3 PF07859.13 ORY11503.1 - 5.5e-27 95.0 0.0 3.1e-24 86.0 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold COesterase PF00135.28 ORY11503.1 - 1.2e-06 27.7 0.0 2.5e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Carboxylesterase family Glyco_transf_90 PF05686.12 ORY11507.1 - 1.6e-20 73.4 0.0 2.3e-20 72.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 Myticin-prepro PF10690.9 ORY11507.1 - 0.064 13.5 0.3 0.14 12.5 0.3 1.5 1 0 0 1 1 1 0 Myticin pre-proprotein from the mussel CENP-B_dimeris PF09026.10 ORY11511.1 - 2.7 8.4 10.9 0.55 10.7 6.2 2.2 2 0 0 2 2 2 0 Centromere protein B dimerisation domain zf-C2H2_4 PF13894.6 ORY11511.1 - 3 8.9 10.8 11 7.2 6.6 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 ORY11511.1 - 4.4 8.0 11.7 15 6.3 7.3 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type DUF2627 PF11118.8 ORY11512.1 - 0.083 13.5 0.7 0.34 11.5 0.7 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2627) SPC12 PF06645.13 ORY11512.1 - 0.26 11.4 5.5 0.68 10.1 5.5 1.7 1 0 0 1 1 1 0 Microsomal signal peptidase 12 kDa subunit (SPC12) DUF1138 PF06592.13 ORY11512.1 - 2 8.5 4.7 1.6 8.9 1.7 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1138) OmpH PF03938.14 ORY11514.1 - 0.0045 17.3 0.3 0.0057 17.0 0.3 1.2 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) FliD_C PF07195.12 ORY11514.1 - 0.0075 15.7 0.2 0.008 15.6 0.2 1.0 1 0 0 1 1 1 1 Flagellar hook-associated protein 2 C-terminus DUF3987 PF13148.6 ORY11514.1 - 0.0079 15.2 0.3 0.0094 15.0 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3987) DUF1351 PF07083.11 ORY11514.1 - 0.011 15.5 0.1 0.014 15.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1351) RACo_C_ter PF14574.6 ORY11514.1 - 0.036 13.1 0.0 0.04 13.0 0.0 1.0 1 0 0 1 1 1 0 C-terminal domain of RACo the ASKHA domain PP_kinase_N PF13089.6 ORY11514.1 - 0.045 14.1 0.1 0.053 13.8 0.1 1.1 1 0 0 1 1 1 0 Polyphosphate kinase N-terminal domain CENP-K PF11802.8 ORY11514.1 - 0.063 12.9 0.1 0.068 12.7 0.1 1.0 1 0 0 1 1 1 0 Centromere-associated protein K Spore_III_AF PF09581.10 ORY11514.1 - 0.073 13.1 0.1 0.083 12.9 0.1 1.0 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) DUF267 PF03268.14 ORY11514.1 - 0.23 10.3 0.1 0.25 10.2 0.1 1.0 1 0 0 1 1 1 0 Caenorhabditis protein of unknown function, DUF267 Sugar_tr PF00083.24 ORY11515.1 - 3e-40 138.5 17.9 6.1e-40 137.4 17.9 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY11515.1 - 1.2e-20 73.8 39.3 1.3e-19 70.4 23.2 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Ribosomal_L37e PF01907.19 ORY11516.1 - 7.6e-23 80.4 12.8 5.1e-13 49.0 0.6 2.3 2 0 0 2 2 2 2 Ribosomal protein L37e zf-ZPR1 PF03367.13 ORY11516.1 - 0.015 15.2 0.1 0.015 15.2 0.1 1.4 2 0 0 2 2 2 0 ZPR1 zinc-finger domain zf-C2H2_3 PF13878.6 ORY11516.1 - 0.059 13.2 3.1 0.68 9.8 0.3 2.4 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO CxC3 PF18804.1 ORY11516.1 - 0.084 12.7 0.4 0.43 10.4 0.3 2.1 2 1 0 2 2 2 0 CxC3 like cysteine cluster associated with KDZ transposases DZR PF12773.7 ORY11516.1 - 0.14 12.2 2.9 0.54 10.3 2.9 1.9 1 1 0 1 1 1 0 Double zinc ribbon zinc_ribbon_2 PF13240.6 ORY11516.1 - 0.15 11.8 1.4 11 5.8 0.2 2.3 2 0 0 2 2 2 0 zinc-ribbon domain ELP6 PF09807.9 ORY11518.1 - 7.2e-06 25.6 0.0 0.00015 21.3 0.0 2.1 2 0 0 2 2 2 1 Elongation complex protein 6 APH_6_hur PF04655.14 ORY11518.1 - 0.016 14.6 0.3 0.027 13.9 0.3 1.4 1 0 0 1 1 1 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase Elong_Iki1 PF10483.9 ORY11518.1 - 0.058 12.9 0.4 0.081 12.4 0.4 1.1 1 0 0 1 1 1 0 Elongator subunit Iki1 TALPID3 PF15324.6 ORY11518.1 - 0.44 8.1 4.6 0.54 7.9 4.6 1.0 1 0 0 1 1 1 0 Hedgehog signalling target RdRP PF05183.12 ORY11519.1 - 1.4e-176 588.6 0.0 1.9e-176 588.2 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase VGPC1_C PF16799.5 ORY11520.1 - 0.045 13.7 0.1 0.13 12.3 0.1 1.7 1 0 0 1 1 1 0 C-terminal membrane-localisation domain of ion-channel, VCN1 2_5_RNA_ligase2 PF13563.6 ORY11520.1 - 0.068 13.1 1.6 0.18 11.7 0.2 2.2 1 1 0 2 2 2 0 2'-5' RNA ligase superfamily Wx5_PLAF3D7 PF09688.10 ORY11520.1 - 0.13 12.2 7.7 0.023 14.7 2.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (Wx5_PLAF3D7) FAD-oxidase_C PF02913.19 ORY11521.1 - 1.6e-67 227.8 0.1 2.4e-67 227.2 0.1 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 ORY11521.1 - 9.8e-33 112.8 0.0 2.1e-32 111.8 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain SepSecS PF05889.13 ORY11521.1 - 0.15 10.7 0.0 0.27 9.9 0.0 1.4 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Semialdhyde_dhC PF02774.18 ORY11522.1 - 6.7e-41 140.4 0.1 8.6e-41 140.0 0.1 1.1 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 ORY11522.1 - 1.6e-28 99.6 0.0 5.1e-28 97.9 0.0 1.8 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DXP_reductoisom PF02670.16 ORY11522.1 - 0.12 13.0 0.0 0.44 11.3 0.0 2.0 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Ribosomal_S4e PF00900.20 ORY11523.1 - 3.4e-37 126.2 0.9 7.7e-37 125.1 0.9 1.6 1 0 0 1 1 1 1 Ribosomal family S4e 40S_S4_C PF16121.5 ORY11523.1 - 4.5e-22 77.4 0.0 7.9e-22 76.6 0.0 1.4 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 ORY11523.1 - 1.5e-17 63.4 6.5 2.7e-17 62.6 6.5 1.4 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.25 ORY11523.1 - 8.8e-07 28.5 0.0 1.7e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 S4 domain KOW PF00467.29 ORY11523.1 - 0.00023 21.0 3.7 0.00023 21.0 3.7 3.1 4 0 0 4 4 4 1 KOW motif SUR7 PF06687.12 ORY11524.1 - 1e-27 97.2 9.2 1.4e-27 96.8 9.2 1.1 1 0 0 1 1 1 1 SUR7/PalI family SCIMP PF15050.6 ORY11524.1 - 0.026 15.0 0.0 0.12 12.8 0.0 2.1 2 0 0 2 2 2 0 SCIMP protein Pox_P21 PF05313.12 ORY11524.1 - 0.075 12.6 1.6 0.14 11.7 1.6 1.3 1 0 0 1 1 1 0 Poxvirus P21 membrane protein HET PF06985.11 ORY11525.1 - 1.5e-24 87.0 0.0 1.8e-24 86.7 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SUR7 PF06687.12 ORY11526.1 - 7.7e-36 123.7 7.7 9.4e-36 123.4 7.7 1.0 1 0 0 1 1 1 1 SUR7/PalI family DUF373 PF04123.13 ORY11526.1 - 0.0053 16.3 0.4 0.0053 16.3 0.4 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF373) Clc-like PF07062.12 ORY11526.1 - 1.2 8.5 11.5 0.025 14.1 4.9 1.5 2 0 0 2 2 2 0 Clc-like Rogdi_lz PF10259.9 ORY11527.1 - 1e-88 297.3 0.0 1.2e-88 297.1 0.0 1.0 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein WXG100 PF06013.12 ORY11527.1 - 0.28 11.4 2.1 1.2 9.4 0.1 2.2 2 0 0 2 2 2 0 Proteins of 100 residues with WXG TP_methylase PF00590.20 ORY11528.1 - 4.6e-46 157.4 0.0 8.5e-46 156.6 0.0 1.4 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.6 ORY11528.1 - 8.9e-15 55.0 0.0 1.7e-14 54.1 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 ORY11528.1 - 1.9e-11 43.4 0.1 2.7e-08 33.3 0.0 2.3 2 0 0 2 2 2 2 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.6 ORY11528.1 - 1.8e-10 40.1 0.1 4.4e-10 38.8 0.1 1.7 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central SAICAR_synt PF01259.18 ORY11529.1 - 2.6e-95 318.8 0.0 3e-95 318.6 0.0 1.0 1 0 0 1 1 1 1 SAICAR synthetase Glyco_hydro_38 PF18438.1 ORY11529.1 - 0.1 12.6 0.1 0.18 11.9 0.1 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 38 C-terminal domain 1 Atg29_N PF18388.1 ORY11531.1 - 3.6e-23 81.1 1.4 8.2e-23 80.0 1.4 1.7 1 0 0 1 1 1 1 Atg29 N-terminal domain SIN1 PF05422.12 ORY11531.1 - 0.076 13.6 1.6 0.14 12.7 1.6 1.4 1 0 0 1 1 1 0 Stress-activated map kinase interacting protein 1 (SIN1) ORC6 PF05460.13 ORY11531.1 - 0.91 8.7 0.0 0.91 8.7 0.0 2.8 3 0 0 3 3 3 0 Origin recognition complex subunit 6 (ORC6) PH_11 PF15413.6 ORY11532.1 - 0.023 15.1 0.1 0.098 13.1 0.0 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain MATalpha_HMGbox PF04769.12 ORY11533.1 - 6.1e-49 166.1 0.0 9.1e-49 165.5 0.0 1.2 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 HMG-box DDR_swiveling PF18427.1 ORY11533.1 - 0.17 11.9 0.0 0.29 11.2 0.0 1.4 1 0 0 1 1 1 0 DD-reactivating factor swiveling domain Exo_endo_phos PF03372.23 ORY11534.1 - 3.9e-10 39.7 0.0 7.7e-10 38.7 0.0 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-GRF PF06839.12 ORY11534.1 - 0.00028 20.9 5.0 0.00069 19.7 5.0 1.7 1 1 0 1 1 1 1 GRF zinc finger Exo_endo_phos_2 PF14529.6 ORY11534.1 - 0.048 13.5 0.0 14 5.5 0.0 2.7 3 0 0 3 3 3 0 Endonuclease-reverse transcriptase CDC27 PF09507.10 ORY11534.1 - 3.6 6.9 10.4 5.1 6.4 10.4 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 COX6A PF02046.15 ORY11535.1 - 8.6e-40 135.7 0.4 1.1e-39 135.4 0.4 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa MRPL52 PF18699.1 ORY11535.1 - 0.12 12.6 0.2 0.25 11.6 0.2 1.5 1 0 0 1 1 1 0 Mitoribosomal protein mL52 ANAPC5 PF12862.7 ORY11536.1 - 9.9e-31 105.7 8.5 1.4e-30 105.2 3.2 3.3 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 5 TPR_19 PF14559.6 ORY11536.1 - 0.001 19.5 6.5 5.2 7.6 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat RPN7 PF10602.9 ORY11536.1 - 0.0025 17.6 0.0 0.01 15.5 0.0 2.2 1 1 0 1 1 1 1 26S proteasome subunit RPN7 TPR_4 PF07721.14 ORY11536.1 - 0.011 16.3 9.5 0.28 11.9 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 ORY11536.1 - 2.2 8.7 4.2 7 7.1 0.1 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 ORY11536.1 - 3.5 8.0 16.1 3.6 7.9 0.1 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 ORY11536.1 - 4.2 7.7 7.5 6 7.2 0.1 4.9 6 0 0 6 6 6 0 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY11536.1 - 9.3 6.6 7.5 11 6.4 0.3 4.0 5 0 0 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 CIA30 PF08547.12 ORY11537.1 - 1.3e-34 119.5 0.0 1.7e-34 119.1 0.0 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) SGBP_B_XBD PF18329.1 ORY11537.1 - 0.029 14.3 0.0 0.062 13.2 0.0 1.5 2 0 0 2 2 2 0 Surface glycan-binding protein B xyloglucan binding domain Mito_carr PF00153.27 ORY11538.1 - 2.5e-70 232.4 2.6 2.9e-22 78.4 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein MBA1 PF07961.11 ORY11539.1 - 1.8e-10 40.3 0.1 1.8e-10 40.3 0.1 1.5 2 0 0 2 2 2 1 MBA1-like protein Tim44 PF04280.15 ORY11539.1 - 2.8e-05 24.2 0.2 0.0044 17.1 0.0 2.3 2 0 0 2 2 2 2 Tim44-like domain SUI1 PF01253.22 ORY11540.1 - 6e-27 94.0 4.3 9.2e-27 93.4 4.3 1.2 1 0 0 1 1 1 1 Translation initiation factor SUI1 UPF0139 PF03669.13 ORY11540.1 - 8.3e-05 22.4 0.0 0.00015 21.6 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) Med12 PF09497.10 ORY11541.1 - 5.7e-25 87.4 1.1 1.5e-24 86.0 0.3 2.3 3 0 0 3 3 3 1 Transcription mediator complex subunit Med12 TFIIA PF03153.13 ORY11541.1 - 0.15 12.0 31.8 0.3 11.1 31.8 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PRIMA1 PF16101.5 ORY11541.1 - 6 6.9 7.0 25 4.9 7.0 2.2 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Pkinase_Tyr PF07714.17 ORY11543.1 - 1.7e-06 27.6 0.0 0.0018 17.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 ORY11543.1 - 2.7e-05 23.7 0.1 0.001 18.5 0.1 2.1 1 1 0 1 1 1 1 Protein kinase domain RhoGAP PF00620.27 ORY11544.1 - 3e-48 163.5 0.0 6.7e-48 162.4 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.23 ORY11544.1 - 1.8e-09 37.7 0.1 5.6e-09 36.1 0.1 1.9 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain Nif11 PF07862.11 ORY11544.1 - 0.24 11.7 7.1 0.22 11.9 0.2 3.6 2 1 1 3 3 3 0 Nif11 domain Putative_PNPOx PF01243.20 ORY11545.1 - 5.1e-10 39.4 0.0 1.1e-08 35.1 0.0 2.4 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Vps5 PF09325.10 ORY11546.1 - 6.9e-87 290.9 2.0 1.1e-86 290.2 2.0 1.3 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 ORY11546.1 - 5.1e-27 94.1 0.4 1.1e-26 93.0 0.1 1.8 2 0 0 2 2 2 1 PX domain BAR_3 PF16746.5 ORY11546.1 - 0.033 13.9 5.4 4 7.1 3.7 2.3 1 1 0 2 2 2 0 BAR domain of APPL family BAR_3_WASP_bdg PF10456.9 ORY11546.1 - 0.058 12.9 0.2 0.13 11.7 0.2 1.6 1 1 0 1 1 1 0 WASP-binding domain of Sorting nexin protein 4HBT PF03061.22 ORY11548.1 - 1.6e-13 50.8 0.2 2.1e-13 50.4 0.2 1.2 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 ORY11548.1 - 0.0016 18.7 0.1 0.0059 16.9 0.0 1.8 1 1 1 2 2 2 1 Thioesterase-like superfamily DUF5321 PF17254.2 ORY11549.1 - 8.2e-57 191.1 5.1 1.1e-56 190.7 5.1 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5321) Aspzincin_M35 PF14521.6 ORY11551.1 - 0.071 13.6 3.7 2.1 8.9 0.0 3.7 3 3 0 3 3 3 0 Lysine-specific metallo-endopeptidase Aldo_ket_red PF00248.21 ORY11556.1 - 6.1e-53 179.9 0.0 6.9e-53 179.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF676 PF05057.14 ORY11556.1 - 0.19 11.2 0.0 0.36 10.3 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) NAD_binding_8 PF13450.6 ORY11557.1 - 1.1e-12 48.0 0.2 3.4e-12 46.4 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ORY11557.1 - 5e-07 29.6 0.2 6.9e-06 25.9 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ORY11557.1 - 7.3e-07 28.7 0.0 7.9e-05 22.0 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ORY11557.1 - 8.4e-05 21.8 0.0 0.00012 21.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.24 ORY11557.1 - 0.0003 20.2 2.0 0.011 15.0 0.0 3.2 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase HI0933_like PF03486.14 ORY11557.1 - 0.00031 19.6 0.1 0.0042 15.8 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 ORY11557.1 - 0.0004 20.9 0.8 1.2 9.8 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ORY11557.1 - 0.00091 19.2 0.1 0.0047 16.9 0.0 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 ORY11557.1 - 0.0037 16.4 0.0 0.007 15.5 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 ORY11557.1 - 0.0066 15.7 0.0 0.015 14.6 0.0 1.5 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 ORY11557.1 - 0.048 12.9 0.0 0.18 11.0 0.0 1.9 2 0 0 2 2 2 0 FAD binding domain FAD_oxidored PF12831.7 ORY11557.1 - 0.085 12.2 0.1 2.3 7.5 0.0 2.5 3 0 0 3 3 3 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 ORY11557.1 - 0.098 11.9 0.0 0.69 9.1 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 ORY11557.1 - 0.19 11.8 0.0 0.44 10.6 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_4 PF07993.12 ORY11558.1 - 4.6e-20 71.9 0.7 4.7e-18 65.3 0.7 2.0 1 1 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 ORY11558.1 - 1.1e-06 28.3 0.1 1.4e-06 28.0 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 ORY11558.1 - 2.9e-06 26.5 0.0 3.7e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 ORY11558.1 - 0.028 14.3 0.0 0.038 13.9 0.0 1.2 1 0 0 1 1 1 0 NAD(P)H-binding AMP-binding PF00501.28 ORY11559.1 - 2e-52 178.2 0.0 2.8e-52 177.7 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 ORY11559.1 - 3.2e-11 43.4 0.0 6.5e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.6 ORY11559.1 - 0.12 13.4 0.0 0.23 12.5 0.0 1.5 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 ORY11560.1 - 5.3e-10 38.5 0.0 5.7e-10 38.4 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme KR PF08659.10 ORY11561.1 - 5.3e-53 179.6 0.0 1.1e-52 178.6 0.0 1.6 1 0 0 1 1 1 1 KR domain Condensation PF00668.20 ORY11561.1 - 5.6e-47 160.4 0.1 1.2e-45 156.1 0.0 2.2 1 1 1 2 2 2 1 Condensation domain Methyltransf_12 PF08242.12 ORY11561.1 - 2.7e-17 63.3 0.0 9.5e-17 61.6 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY11561.1 - 8.5e-15 55.0 0.0 1.9e-14 53.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY11561.1 - 1.2e-12 48.3 0.0 1.3e-11 45.0 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY11561.1 - 3.6e-11 43.6 0.0 2.1e-10 41.1 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain adh_short PF00106.25 ORY11561.1 - 5.8e-11 42.2 0.0 3.4e-10 39.7 0.0 2.3 3 0 0 3 3 3 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY11561.1 - 5.3e-07 29.4 0.0 9.8e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Methyltransf_31 PF13847.6 ORY11561.1 - 1.3e-06 28.3 0.0 3.7e-06 26.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 ORY11561.1 - 2e-06 28.1 0.1 1.1e-05 25.7 0.0 2.3 2 0 0 2 2 2 1 Phosphopantetheine attachment site Ubie_methyltran PF01209.18 ORY11561.1 - 1.5e-05 24.5 0.0 2.9e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family NodS PF05401.11 ORY11561.1 - 0.05 13.2 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Nodulation protein S (NodS) Tri3 PF07428.11 ORY11561.1 - 0.055 12.4 0.1 0.096 11.6 0.1 1.3 1 0 0 1 1 1 0 15-O-acetyltransferase Tri3 DAO PF01266.24 ORY11580.1 - 0.026 14.1 0.0 0.036 13.6 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Dynactin PF12455.8 ORY11581.1 - 1.8e-44 152.1 4.3 1.8e-44 152.1 4.3 3.8 3 1 0 3 3 3 1 Dynein associated protein CAP_GLY PF01302.25 ORY11581.1 - 2e-22 78.9 0.3 3.5e-22 78.2 0.3 1.4 1 0 0 1 1 1 1 CAP-Gly domain Vps4_C PF09336.10 ORY11581.1 - 0.13 12.3 0.4 28 4.8 0.0 3.9 4 0 0 4 4 4 0 Vps4 C terminal oligomerisation domain CopK PF11525.8 ORY11581.1 - 0.18 11.4 1.5 12 5.6 0.4 2.7 2 0 0 2 2 2 0 Copper resistance protein K GAS PF13851.6 ORY11581.1 - 2.7 7.3 79.5 0.16 11.3 19.2 4.8 3 1 1 4 4 4 0 Growth-arrest specific micro-tubule binding ABC_membrane_2 PF06472.15 ORY11582.1 - 6.4e-104 347.1 2.0 1e-103 346.5 2.0 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 ORY11582.1 - 2.9e-19 69.9 0.0 5.4e-19 69.1 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ORY11582.1 - 5.5e-05 23.1 0.1 0.00026 20.9 0.0 2.2 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 ORY11582.1 - 0.0036 17.8 0.1 0.012 16.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 ORY11582.1 - 0.029 14.1 0.0 0.069 12.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain SMC_N PF02463.19 ORY11582.1 - 0.044 13.2 0.4 0.15 11.5 0.0 2.0 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain RuvB_N PF05496.12 ORY11582.1 - 0.074 12.8 0.0 1 9.1 0.0 2.6 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain Reticulon PF02453.17 ORY11582.1 - 0.082 12.9 0.1 0.19 11.7 0.1 1.5 1 0 0 1 1 1 0 Reticulon AAA_27 PF13514.6 ORY11582.1 - 0.088 12.4 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 ORY11582.1 - 0.092 13.1 1.5 1 9.7 0.1 2.6 3 0 0 3 3 3 0 AAA ATPase domain Rad17 PF03215.15 ORY11582.1 - 0.11 12.5 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain Mg_chelatase PF01078.21 ORY11582.1 - 0.21 10.9 0.0 0.58 9.5 0.0 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_15 PF13175.6 ORY11582.1 - 0.21 11.3 0.0 0.45 10.2 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain HET PF06985.11 ORY11583.1 - 1.6e-06 28.5 0.1 2.7e-06 27.8 0.1 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Tektin PF03148.14 ORY11583.1 - 0.16 10.7 0.0 0.26 10.0 0.0 1.2 1 0 0 1 1 1 0 Tektin family Xin PF08043.12 ORY11586.1 - 0.34 10.6 1.3 5.2 6.9 0.0 2.4 2 0 0 2 2 2 0 Xin repeat RabGAP-TBC PF00566.18 ORY11587.1 - 8.8e-51 172.6 2.2 1.2e-49 168.9 0.0 2.8 3 0 0 3 3 3 1 Rab-GTPase-TBC domain DUF4653 PF15546.6 ORY11587.1 - 0.012 15.3 2.0 0.012 15.3 2.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4653) Shugoshin_N PF07558.11 ORY11587.1 - 0.72 9.8 3.2 1.4 8.8 0.4 2.6 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region HALZ PF02183.18 ORY11587.1 - 0.74 10.1 11.3 0.41 10.9 0.7 3.5 4 0 0 4 4 4 0 Homeobox associated leucine zipper Cnn_1N PF07989.11 ORY11587.1 - 1.2 9.3 30.2 0.049 13.8 10.5 3.5 2 1 1 3 3 3 0 Centrosomin N-terminal motif 1 FlaC_arch PF05377.11 ORY11587.1 - 1.4 9.4 14.5 4.7 7.7 2.3 3.5 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Fez1 PF06818.15 ORY11587.1 - 3.4 8.1 31.0 2.3 8.6 25.5 2.3 2 0 0 2 2 2 0 Fez1 GP41 PF00517.17 ORY11587.1 - 5.1 6.9 9.5 9 6.1 9.2 1.5 1 1 0 1 1 1 0 Retroviral envelope protein Mago_nashi PF02792.14 ORY11587.1 - 6.5 6.9 6.4 0.44 10.7 0.4 2.0 2 0 0 2 2 2 0 Mago nashi protein KH_1 PF00013.29 ORY11588.1 - 2e-49 165.3 12.6 3.4e-16 58.8 0.4 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 ORY11588.1 - 7.6e-14 51.3 2.8 0.0014 18.4 0.0 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 ORY11588.1 - 8.7e-09 35.1 3.3 0.039 13.8 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 ORY11588.1 - 0.001 19.1 4.3 3.6 7.7 0.1 3.4 3 0 0 3 3 3 3 NusA-like KH domain MOEP19 PF16005.5 ORY11588.1 - 0.0015 18.5 0.0 1.8 8.6 0.0 3.1 3 0 0 3 3 3 2 KH-like RNA-binding domain Ald_Xan_dh_C2 PF02738.18 ORY11589.1 - 8.4e-206 684.7 2.2 1.2e-205 684.2 2.2 1.2 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.21 ORY11589.1 - 8.5e-46 155.8 0.0 1.7e-45 154.9 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.17 ORY11589.1 - 6e-32 109.9 0.1 1.8e-31 108.4 0.1 1.9 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain Ald_Xan_dh_C PF01315.22 ORY11589.1 - 6.9e-31 106.9 0.0 1.8e-30 105.5 0.0 1.8 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.20 ORY11589.1 - 3.5e-29 100.6 0.1 7.8e-29 99.5 0.1 1.6 1 0 0 1 1 1 1 [2Fe-2S] binding domain Fer2 PF00111.27 ORY11589.1 - 1.3e-07 31.5 2.4 1.4e-07 31.4 0.1 2.3 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Sigma70_r3 PF04539.16 ORY11589.1 - 0.11 12.7 0.0 0.31 11.2 0.0 1.8 1 0 0 1 1 1 0 Sigma-70 region 3 HMGL-like PF00682.19 ORY11590.1 - 6.8e-43 147.1 0.0 4e-32 111.8 0.1 2.0 2 0 0 2 2 2 2 HMGL-like Jacalin PF01419.17 ORY11591.1 - 8.9e-05 22.4 0.1 0.00015 21.7 0.1 1.3 1 0 0 1 1 1 1 Jacalin-like lectin domain SSP160 PF06933.11 ORY11592.1 - 6.1 4.9 9.4 0.31 9.2 2.6 1.8 2 0 0 2 2 2 0 Special lobe-specific silk protein SSP160 V-SNARE PF05008.15 ORY11596.1 - 3.1e-19 69.1 1.7 3.1e-19 69.1 1.7 2.0 3 0 0 3 3 3 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.8 ORY11596.1 - 3.9e-16 59.1 6.6 3.9e-16 59.1 6.6 2.6 3 1 1 4 4 4 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 ORY11596.1 - 0.018 14.9 1.4 0.054 13.4 0.7 2.1 1 1 1 2 2 2 0 Sec20 Fusion_gly PF00523.18 ORY11596.1 - 0.023 13.0 0.2 0.041 12.1 0.2 1.5 1 0 0 1 1 1 0 Fusion glycoprotein F0 Use1 PF09753.9 ORY11596.1 - 0.027 14.2 8.7 0.19 11.4 8.7 1.9 1 1 0 1 1 1 0 Membrane fusion protein Use1 RRF PF01765.19 ORY11596.1 - 0.027 14.4 0.5 0.057 13.4 0.5 1.6 1 0 0 1 1 1 0 Ribosome recycling factor Prominin PF05478.11 ORY11596.1 - 0.03 12.3 1.2 3 5.7 0.0 2.0 2 0 0 2 2 2 0 Prominin Spectrin PF00435.21 ORY11596.1 - 0.047 14.2 3.2 0.14 12.7 0.2 2.6 1 1 2 3 3 3 0 Spectrin repeat SNARE PF05739.19 ORY11596.1 - 0.057 13.4 1.4 0.32 11.0 0.6 2.3 2 0 0 2 2 2 0 SNARE domain Synaptobrevin PF00957.21 ORY11596.1 - 0.14 11.9 2.9 0.12 12.2 0.5 2.0 2 0 0 2 2 2 0 Synaptobrevin Tropomyosin_1 PF12718.7 ORY11596.1 - 0.22 11.7 9.5 0.066 13.4 1.4 2.9 1 1 2 3 3 3 0 Tropomyosin like YqjK PF13997.6 ORY11596.1 - 0.39 11.0 0.1 0.39 11.0 0.1 2.4 2 0 0 2 2 2 0 YqjK-like protein TBCA PF02970.16 ORY11596.1 - 0.41 11.0 0.2 0.41 11.0 0.2 2.7 2 1 1 3 3 3 0 Tubulin binding cofactor A NAD_binding_8 PF13450.6 ORY11597.1 - 2.5e-12 46.8 0.0 8.6e-12 45.1 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 ORY11597.1 - 1.3e-06 28.1 0.3 3.7e-05 23.2 0.0 2.7 2 1 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 ORY11597.1 - 4.8e-05 22.7 0.0 0.00019 20.8 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ORY11597.1 - 0.0003 20.5 0.2 0.0031 17.2 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 ORY11597.1 - 0.00098 19.1 0.2 0.015 15.3 0.1 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 ORY11597.1 - 0.0065 15.6 0.1 0.018 14.1 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain FMO-like PF00743.19 ORY11597.1 - 0.045 12.2 0.0 0.07 11.5 0.0 1.2 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like AlaDh_PNT_C PF01262.21 ORY11597.1 - 0.08 12.2 0.0 0.18 11.1 0.0 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 ORY11597.1 - 0.11 11.1 0.0 0.65 8.6 0.0 1.9 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox PF00070.27 ORY11597.1 - 0.13 12.8 0.0 0.34 11.5 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Ribosomal_L37ae PF01780.19 ORY11598.1 - 1.8e-41 140.1 12.0 2e-41 140.0 12.0 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family zf-RING_13 PF17977.1 ORY11598.1 - 0.00047 20.2 1.9 0.00066 19.8 1.9 1.2 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Zn_Tnp_IS1595 PF12760.7 ORY11598.1 - 0.0061 16.5 3.0 0.011 15.7 3.0 1.5 1 0 0 1 1 1 1 Transposase zinc-ribbon domain Ima1_N PF09779.9 ORY11598.1 - 0.015 16.2 0.1 0.02 15.7 0.1 1.3 1 0 0 1 1 1 0 Ima1 N-terminal domain DUF1451 PF07295.11 ORY11598.1 - 0.016 15.2 0.9 0.022 14.8 0.9 1.2 1 0 0 1 1 1 0 Zinc-ribbon containing domain zf-H2C2_2 PF13465.6 ORY11598.1 - 0.049 14.1 5.8 0.75 10.3 0.9 2.3 1 1 1 2 2 2 0 Zinc-finger double domain zf-BED PF02892.15 ORY11598.1 - 0.078 13.0 5.2 2.4 8.3 0.5 2.2 1 1 1 2 2 2 0 BED zinc finger CarbpepA_inh PF02977.15 ORY11598.1 - 0.81 9.5 4.7 4.9 7.0 4.7 2.0 1 1 0 1 1 1 0 Carboxypeptidase A inhibitor RIBIOP_C PF04950.12 ORY11599.1 - 4.7e-107 357.8 0.0 1.4e-106 356.2 0.0 1.8 2 0 0 2 2 2 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 ORY11599.1 - 2.7e-20 72.3 0.0 6.4e-20 71.0 0.0 1.6 1 0 0 1 1 1 1 AARP2CN (NUC121) domain Stc1 PF12898.7 ORY11600.1 - 2.7e-19 69.5 13.8 2.7e-19 69.5 13.8 1.7 2 0 0 2 2 2 1 Stc1 domain Imm-NTF2 PF15655.6 ORY11601.1 - 0.0098 16.2 0.1 0.043 14.1 0.0 2.1 2 0 0 2 2 2 1 NTF2 fold immunity protein DUF1699 PF08004.11 ORY11601.1 - 0.14 11.8 0.3 12 5.6 0.0 3.4 3 1 1 4 4 4 0 Protein of unknown function (DUF1699) GATA PF00320.27 ORY11601.1 - 0.3 10.7 2.3 0.29 10.8 0.8 1.8 2 0 0 2 2 2 0 GATA zinc finger LRR_1 PF00560.33 ORY11601.1 - 0.32 11.7 9.4 50 5.0 0.0 6.4 6 1 0 6 6 6 0 Leucine Rich Repeat AP3D1 PF06375.11 ORY11601.1 - 4 7.7 10.8 1.3 9.2 8.1 1.6 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 DTHCT PF08070.11 ORY11601.1 - 4.1 8.2 15.7 0.64 10.8 10.1 2.1 2 0 0 2 2 2 0 DTHCT (NUC029) region S10_plectin PF03501.15 ORY11602.1 - 1.5e-41 140.4 0.1 1.8e-41 140.1 0.1 1.0 1 0 0 1 1 1 1 Plectin/S10 domain GRP PF07172.11 ORY11602.1 - 8.6 7.1 12.8 13 6.6 12.8 1.3 1 0 0 1 1 1 0 Glycine rich protein family Sde2_N_Ubi PF13019.6 ORY11603.1 - 2.9e-56 189.8 0.5 5e-56 189.0 0.5 1.4 1 0 0 1 1 1 1 Silencing defective 2 N-terminal ubiquitin domain Cep57_MT_bd PF06657.13 ORY11603.1 - 0.063 13.7 2.4 0.14 12.6 2.4 1.6 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 DNA_pol3_delta2 PF13177.6 ORY11605.1 - 3.7e-11 43.1 0.0 8.5e-11 41.9 0.0 1.6 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 ORY11605.1 - 1.3e-06 28.8 0.2 3.9e-06 27.3 0.1 1.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 ORY11605.1 - 8.7e-06 26.1 0.6 0.00078 19.7 0.1 2.6 2 1 0 2 2 2 1 AAA domain Rep_fac_C PF08542.11 ORY11605.1 - 7.4e-05 23.1 0.0 0.00024 21.4 0.0 1.9 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA_16 PF13191.6 ORY11605.1 - 0.00035 21.0 1.3 0.0078 16.6 0.4 2.8 2 1 0 2 2 2 1 AAA ATPase domain Rad17 PF03215.15 ORY11605.1 - 0.002 18.1 0.0 0.017 15.1 0.0 2.1 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_24 PF13479.6 ORY11605.1 - 0.0022 17.8 0.6 0.008 15.9 0.2 2.0 2 1 0 2 2 2 1 AAA domain ABC_tran PF00005.27 ORY11605.1 - 0.032 14.8 0.1 0.082 13.4 0.0 1.9 1 1 0 1 1 1 0 ABC transporter T4SS-DNA_transf PF02534.14 ORY11605.1 - 0.091 11.5 0.0 0.19 10.5 0.0 1.5 2 0 0 2 2 2 0 Type IV secretory system Conjugative DNA transfer ADH_N PF08240.12 ORY11606.1 - 6.3e-25 87.2 1.5 1.1e-24 86.4 1.5 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORY11606.1 - 1.8e-21 76.5 0.9 2.7e-21 75.9 0.9 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ORY11606.1 - 0.0052 17.8 0.7 0.0088 17.1 0.7 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 ORY11606.1 - 0.0089 15.9 0.1 0.021 14.7 0.1 1.6 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase Pkinase PF00069.25 ORY11607.1 - 1e-67 228.3 0.0 1.9e-67 227.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY11607.1 - 1.2e-46 159.1 0.0 1.9e-46 158.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.6 ORY11607.1 - 1.4e-27 96.0 0.0 2.7e-27 95.0 0.0 1.5 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_2 PF07647.17 ORY11607.1 - 2e-15 56.7 0.6 4.6e-15 55.5 0.6 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 ORY11607.1 - 3.6e-15 56.1 1.7 7e-15 55.2 1.7 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Kinase-like PF14531.6 ORY11607.1 - 2e-07 30.6 0.0 0.00022 20.6 0.0 2.4 2 0 0 2 2 2 2 Kinase-like RA PF00788.23 ORY11607.1 - 0.0074 16.9 0.0 0.015 15.9 0.0 1.6 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain IGR PF09597.10 ORY11607.1 - 0.027 14.6 0.1 0.059 13.5 0.1 1.5 1 0 0 1 1 1 0 IGR protein motif Seadorna_VP7 PF07387.11 ORY11607.1 - 0.086 11.9 0.0 0.19 10.7 0.0 1.5 1 0 0 1 1 1 0 Seadornavirus VP7 SAM_4 PF18017.1 ORY11607.1 - 0.087 12.8 0.3 0.19 11.7 0.3 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Peptidase_M20 PF01546.28 ORY11610.1 - 3.4e-29 102.0 0.0 5e-29 101.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 ORY11610.1 - 0.007 16.3 0.0 0.016 15.1 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 ORY11610.1 - 0.012 15.4 0.0 0.019 14.6 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M28 Homeodomain PF00046.29 ORY11613.1 - 1.7e-14 53.4 0.2 3.5e-14 52.4 0.2 1.5 1 0 0 1 1 1 1 Homeodomain MFS18 PF17352.2 ORY11613.1 - 0.0041 17.5 6.0 0.0093 16.3 6.0 1.6 1 0 0 1 1 1 1 Male Flower Specific protein 18 Homeobox_KN PF05920.11 ORY11613.1 - 0.19 11.7 1.2 0.31 11.0 0.2 1.9 2 0 0 2 2 2 0 Homeobox KN domain zf-C4H2 PF10146.9 ORY11614.1 - 0.56 10.5 6.2 2.5 8.4 6.2 2.0 1 1 0 1 1 1 0 Zinc finger-containing protein Asp PF00026.23 ORY11615.1 - 6.3e-44 150.7 0.1 8.2e-44 150.3 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 ORY11615.1 - 6.1e-08 33.1 4.4 5.4e-06 26.8 4.4 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 ORY11615.1 - 4.5e-06 26.5 0.0 6.8e-05 22.7 0.0 2.3 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Glu-tRNAGln PF02686.15 ORY11617.1 - 5.8e-10 39.3 2.9 5.7e-09 36.1 2.9 2.4 1 1 0 1 1 1 1 Glu-tRNAGln amidotransferase C subunit SNAP PF14938.6 ORY11618.1 - 5.5e-112 373.8 15.4 6.2e-112 373.6 15.4 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP Spatacsin_C PF14649.6 ORY11618.1 - 0.00069 18.8 8.5 0.13 11.3 0.0 3.0 1 1 1 2 2 2 2 Spatacsin C-terminus NAPRTase PF04095.16 ORY11618.1 - 0.0086 15.7 0.2 0.66 9.5 0.2 2.2 1 1 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family TPR_8 PF13181.6 ORY11618.1 - 0.042 14.1 0.8 0.042 14.1 0.8 4.3 6 1 1 7 7 7 0 Tetratricopeptide repeat TPR_3 PF07720.12 ORY11618.1 - 0.14 12.2 8.4 2.9 8.0 0.3 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 ORY11618.1 - 0.27 11.4 10.5 3.1 8.0 1.1 4.7 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 ORY11618.1 - 0.42 10.9 19.2 5.5 7.3 0.2 6.0 6 1 1 7 7 7 0 Tetratricopeptide repeat PAPA-1 PF04795.12 ORY11620.1 - 3.6e-28 98.2 3.5 3.6e-28 98.2 3.5 4.0 3 2 0 3 3 3 1 PAPA-1-like conserved region Pex14_N PF04695.13 ORY11621.1 - 4.3e-36 125.0 1.4 4.3e-36 125.0 1.4 2.9 2 1 1 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Tropomyosin PF00261.20 ORY11621.1 - 0.075 12.4 0.5 0.27 10.6 0.1 1.9 2 0 0 2 2 2 0 Tropomyosin DASH_Hsk3 PF08227.11 ORY11621.1 - 0.16 12.4 2.4 11 6.4 0.0 2.9 3 0 0 3 3 3 0 DASH complex subunit Hsk3 like DUF4404 PF14357.6 ORY11621.1 - 2 9.1 5.7 5.2 7.8 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) DUF726 PF05277.12 ORY11622.1 - 2e-128 428.2 0.3 2.7e-128 427.7 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Thioesterase PF00975.20 ORY11622.1 - 0.0045 17.1 0.2 0.018 15.1 0.0 2.0 2 0 0 2 2 2 1 Thioesterase domain Abhydrolase_6 PF12697.7 ORY11622.1 - 0.048 14.3 3.2 0.11 13.1 0.0 2.2 1 1 0 2 2 2 0 Alpha/beta hydrolase family RR_TM4-6 PF06459.12 ORY11622.1 - 7.1 6.4 31.4 3.7 7.3 9.4 2.5 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Fungal_trans_2 PF11951.8 ORY11624.1 - 2.7e-55 187.7 0.1 3.7e-55 187.3 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY11624.1 - 3.6e-08 33.4 7.1 6.6e-08 32.6 7.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UvdE PF03851.14 ORY11625.1 - 4.1e-110 367.4 0.0 5.2e-110 367.0 0.0 1.1 1 0 0 1 1 1 1 UV-endonuclease UvdE PHC2_SAM_assoc PF16616.5 ORY11625.1 - 0.00076 20.3 0.8 0.0034 18.2 0.4 2.4 1 1 0 1 1 1 1 Unstructured region on Polyhomeotic-like protein 1 and 2 BRF1 PF07741.13 ORY11625.1 - 0.63 10.4 3.8 0.45 10.9 0.3 2.7 2 0 0 2 2 2 0 Brf1-like TBP-binding domain DUF1757 PF08560.10 ORY11626.1 - 1.8e-06 28.1 0.0 2.3e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1757) YdjM PF04307.14 ORY11626.1 - 0.099 11.9 0.8 0.15 11.3 0.7 1.4 1 1 0 1 1 1 0 LexA-binding, inner membrane-associated putative hydrolase Abhydrolase_1 PF00561.20 ORY11627.1 - 2.7e-16 60.0 0.0 1.2e-13 51.3 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ORY11627.1 - 2.2e-11 43.5 0.0 1.8e-10 40.5 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ORY11627.1 - 1.7e-10 41.9 0.0 2.2e-10 41.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 ORY11627.1 - 0.0046 16.6 0.0 0.011 15.4 0.0 1.5 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_2 PF02230.16 ORY11627.1 - 0.0091 15.8 0.0 0.37 10.6 0.0 2.5 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Ndr PF03096.14 ORY11627.1 - 0.013 14.2 0.0 0.098 11.3 0.0 2.0 1 1 0 1 1 1 0 Ndr family C2 PF00168.30 ORY11628.1 - 9.6e-28 96.5 0.0 1.7e-16 60.4 0.0 2.8 3 0 0 3 3 3 2 C2 domain GDPD PF03009.17 ORY11628.1 - 0.0054 16.5 0.3 0.011 15.5 0.3 1.5 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Amidohydro_3 PF07969.11 ORY11629.1 - 4.2e-07 29.8 0.0 7.3e-05 22.4 0.0 3.0 3 0 0 3 3 3 1 Amidohydrolase family Amidohydro_1 PF01979.20 ORY11629.1 - 3e-05 23.5 0.0 4.1e-05 23.0 0.0 1.3 1 1 0 1 1 1 1 Amidohydrolase family MatE PF01554.18 ORY11630.1 - 8.5e-60 201.1 20.0 9.1e-32 109.9 6.4 2.2 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 ORY11630.1 - 0.00011 22.3 16.1 0.00011 22.3 16.1 4.3 3 2 2 5 5 5 1 Polysaccharide biosynthesis C-terminal domain Arginase PF00491.21 ORY11631.1 - 1.9e-91 306.5 0.0 2.4e-91 306.1 0.0 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 ORY11631.1 - 0.065 13.5 0.1 0.13 12.4 0.1 1.4 1 1 0 1 1 1 0 UPF0489 domain Fe-S_biosyn PF01521.20 ORY11632.1 - 1.1e-16 61.0 0.0 1.4e-16 60.6 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis zf-C2H2_6 PF13912.6 ORY11632.1 - 0.098 12.7 0.3 0.098 12.7 0.3 1.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_4 PF13894.6 ORY11632.1 - 3.3 8.8 5.3 1.1 10.2 0.8 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger DUF2407_C PF13373.6 ORY11633.1 - 3.1e-39 134.3 0.0 5.8e-39 133.5 0.0 1.4 1 0 0 1 1 1 1 DUF2407 C-terminal domain DUF2407 PF10302.9 ORY11633.1 - 8.8e-32 109.8 0.0 2e-31 108.6 0.0 1.6 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.23 ORY11633.1 - 4.8e-05 23.0 0.0 8.7e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD_2 PF13881.6 ORY11633.1 - 0.081 13.0 0.1 0.18 11.9 0.0 1.6 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like SOG2 PF10428.9 ORY11633.1 - 0.43 9.7 5.8 0.5 9.5 5.8 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Arc PF03869.14 ORY11634.1 - 0.11 12.3 0.1 0.97 9.3 0.0 2.1 2 0 0 2 2 2 0 Arc-like DNA binding domain SPO22 PF08631.10 ORY11635.1 - 1.1e-69 235.0 12.6 1.1e-69 235.0 12.6 3.9 5 0 0 5 5 5 1 Meiosis protein SPO22/ZIP4 like TPR_19 PF14559.6 ORY11635.1 - 0.00015 22.2 0.2 0.00015 22.2 0.2 4.6 4 2 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY11635.1 - 0.0039 17.4 4.4 0.23 11.7 1.6 3.5 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 ORY11635.1 - 0.0042 17.2 2.6 3.6 8.0 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 ORY11635.1 - 0.0078 15.9 0.0 0.032 13.9 0.0 2.1 1 0 0 1 1 1 1 TPR repeat TPR_6 PF13174.6 ORY11635.1 - 0.018 15.7 2.0 2.7 8.8 0.1 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat PPR_long PF17177.4 ORY11635.1 - 0.024 14.0 2.9 0.23 10.8 0.4 2.7 2 0 0 2 2 2 0 Pentacotripeptide-repeat region of PRORP Sel1 PF08238.12 ORY11635.1 - 0.12 13.1 4.0 0.97 10.2 0.3 3.7 3 0 0 3 3 3 0 Sel1 repeat TPR_14 PF13428.6 ORY11635.1 - 0.46 11.4 0.0 0.46 11.4 0.0 6.4 7 1 2 9 9 9 0 Tetratricopeptide repeat TPR_16 PF13432.6 ORY11635.1 - 0.49 11.1 3.7 1.4 9.6 0.0 3.6 3 2 1 4 4 4 0 Tetratricopeptide repeat Zn_clus PF00172.18 ORY11636.1 - 0.13 12.5 2.2 0.23 11.6 2.2 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain CENP-Q PF13094.6 ORY11638.1 - 4.5e-28 98.6 3.7 4.5e-28 98.6 3.7 2.1 2 0 0 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit RecQ5 PF06959.11 ORY11638.1 - 0.025 14.5 4.5 0.052 13.5 4.5 1.5 1 0 0 1 1 1 0 RecQ helicase protein-like 5 (RecQ5) HGD-D PF06050.13 ORY11638.1 - 0.037 13.8 0.0 3.5 7.3 0.0 2.2 1 1 1 2 2 2 0 2-hydroxyglutaryl-CoA dehydratase, D-component TRAF_BIRC3_bd PF16673.5 ORY11638.1 - 0.09 12.6 0.5 0.24 11.2 0.5 1.7 1 0 0 1 1 1 0 TNF receptor-associated factor BIRC3 binding domain GrpE PF01025.19 ORY11638.1 - 0.29 10.8 5.7 2.5 7.8 0.0 3.0 3 0 0 3 3 3 0 GrpE Phage_GP20 PF06810.11 ORY11638.1 - 3.5 7.4 11.1 0.051 13.4 1.3 2.8 4 0 0 4 4 4 0 Phage minor structural protein GP20 HSP70 PF00012.20 ORY11639.1 - 6.5e-12 44.4 0.0 2.3e-10 39.3 0.0 2.0 2 0 0 2 2 2 2 Hsp70 protein FtsA PF14450.6 ORY11639.1 - 0.0002 21.7 0.1 0.0043 17.4 0.0 2.4 2 0 0 2 2 2 1 Cell division protein FtsA MreB_Mbl PF06723.13 ORY11639.1 - 0.011 14.6 0.0 0.066 12.0 0.0 1.9 2 0 0 2 2 2 0 MreB/Mbl protein DUF2985 PF11204.8 ORY11640.1 - 0.18 12.0 0.0 0.32 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2985) CHAD PF05235.14 ORY11640.1 - 2.1 8.3 11.6 8.1 6.3 11.5 2.1 1 1 0 1 1 1 0 CHAD domain DUF4407 PF14362.6 ORY11640.1 - 2.5 7.4 6.9 35 3.6 7.1 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4472 PF14739.6 ORY11640.1 - 5.4 7.8 12.9 6.2 7.6 0.3 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF4472) RINGv PF12906.7 ORY11641.1 - 4.9e-10 39.4 4.4 2.3e-09 37.2 1.7 2.2 2 0 0 2 2 2 1 RING-variant domain zf-RING_2 PF13639.6 ORY11641.1 - 0.018 15.4 5.1 1 9.7 1.6 2.2 2 0 0 2 2 2 0 Ring finger domain PHD_4 PF16866.5 ORY11641.1 - 0.052 13.6 2.3 0.75 9.9 1.5 2.2 2 0 0 2 2 2 0 PHD-finger zf-C3HC4 PF00097.25 ORY11641.1 - 0.3 11.0 2.2 3.7 7.5 2.2 2.2 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) EI24 PF07264.11 ORY11641.1 - 0.72 10.1 5.3 0.11 12.8 1.3 1.6 1 1 1 2 2 2 0 Etoposide-induced protein 2.4 (EI24) PHD PF00628.29 ORY11641.1 - 1.1 9.2 5.7 0.26 11.2 2.0 1.8 2 0 0 2 2 2 0 PHD-finger Proteasome PF00227.26 ORY11642.1 - 1.3e-56 191.1 0.1 2.4e-32 112.0 0.0 2.2 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.9 ORY11642.1 - 9.2e-11 41.2 0.1 3.1e-10 39.5 0.0 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Ribonuclease_3 PF00636.26 ORY11643.1 - 6e-42 142.5 0.2 4.2e-20 72.3 0.0 3.2 3 0 0 3 3 3 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 ORY11643.1 - 2.5e-26 92.3 1.4 5.2e-11 42.8 0.0 4.3 4 0 0 4 4 4 3 Ribonuclease-III-like Dicer_dimer PF03368.14 ORY11643.1 - 3.1e-23 81.7 0.0 2.1e-22 79.1 0.0 2.4 2 0 0 2 2 2 1 Dicer dimerisation domain DEAD PF00270.29 ORY11643.1 - 1.5e-17 63.9 0.0 3.2e-17 62.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 ORY11643.1 - 5.7e-17 62.2 0.0 1.8e-16 60.6 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 ORY11643.1 - 1.5e-13 51.0 0.0 3.6e-13 49.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 ORY11643.1 - 0.017 15.4 0.0 0.086 13.1 0.0 2.2 1 0 0 1 1 1 0 AAA domain DUF3638 PF12340.8 ORY11643.1 - 0.024 13.9 0.0 0.044 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3638) N-glycanase_N PF09112.10 ORY11643.1 - 0.15 11.9 0.0 0.86 9.4 0.0 2.2 3 0 0 3 3 3 0 Peptide-N-glycosidase F, N terminal DEAD_2 PF06733.15 ORY11643.1 - 0.17 11.5 0.1 0.39 10.3 0.1 1.5 1 0 0 1 1 1 0 DEAD_2 Big_1 PF02369.16 ORY11644.1 - 0.019 15.0 0.0 4.1 7.5 0.0 2.5 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 1) zf-CCHC_5 PF14787.6 ORY11644.1 - 0.2 11.4 2.3 7.3 6.4 0.3 2.4 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger Utp12 PF04003.12 ORY11645.1 - 7.9e-27 93.7 0.1 1.2e-26 93.1 0.1 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family MutL_C PF08676.11 ORY11645.1 - 0.12 12.1 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 MutL C terminal dimerisation domain SDA1 PF05285.12 ORY11645.1 - 3.8 6.9 36.3 0.32 10.4 4.2 2.2 2 0 0 2 2 2 0 SDA1 Bromodomain PF00439.25 ORY11646.1 - 3.5e-41 139.2 0.9 2.6e-20 72.2 0.2 2.5 2 0 0 2 2 2 2 Bromodomain BET PF17035.5 ORY11646.1 - 5.1e-19 68.2 0.7 8.5e-19 67.5 0.1 1.8 2 0 0 2 2 2 1 Bromodomain extra-terminal - transcription regulation DUF4407 PF14362.6 ORY11646.1 - 0.084 12.2 0.6 0.17 11.2 0.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) BLOC1_2 PF10046.9 ORY11646.1 - 9.1 6.7 7.5 11 6.4 4.5 2.3 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TIP49 PF06068.13 ORY11648.1 - 1.6e-162 540.6 0.0 2e-162 540.3 0.0 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 ORY11648.1 - 7.9e-19 67.6 0.0 1.7e-18 66.5 0.0 1.6 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 ORY11648.1 - 4.4e-11 43.3 0.1 1.4e-07 32.0 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 ORY11648.1 - 1.8e-09 37.5 0.1 1.1e-06 28.5 0.0 2.3 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 ORY11648.1 - 2.3e-05 24.7 0.2 0.22 11.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 ORY11648.1 - 3.4e-05 24.3 0.5 0.00068 20.1 0.5 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.6 ORY11648.1 - 5.3e-05 23.6 0.5 0.061 13.6 0.2 2.4 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 ORY11648.1 - 0.00042 20.3 0.2 0.2 11.7 0.1 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 ORY11648.1 - 0.0011 19.3 0.1 0.0025 18.1 0.1 1.6 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 ORY11648.1 - 0.0039 16.9 0.1 1.4 8.6 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain Zeta_toxin PF06414.12 ORY11648.1 - 0.0064 15.8 0.3 0.015 14.6 0.2 1.6 2 0 0 2 2 2 1 Zeta toxin Mg_chelatase PF01078.21 ORY11648.1 - 0.024 14.0 0.3 0.7 9.2 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 ORY11648.1 - 0.024 14.2 0.0 0.046 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain DnaB_C PF03796.15 ORY11648.1 - 0.041 13.2 0.0 0.069 12.5 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_30 PF13604.6 ORY11648.1 - 0.044 13.5 0.1 0.52 10.0 0.1 2.3 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 ORY11648.1 - 0.057 12.8 0.5 0.14 11.5 0.1 1.8 2 0 0 2 2 2 0 KaiC IstB_IS21 PF01695.17 ORY11648.1 - 0.062 13.0 0.1 0.13 12.0 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF2075 PF09848.9 ORY11648.1 - 0.07 12.4 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_18 PF13238.6 ORY11648.1 - 0.11 13.0 0.0 0.29 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 ORY11648.1 - 0.12 11.9 0.2 0.5 9.8 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF1674 PF07896.12 ORY11649.1 - 4.4e-20 71.9 4.1 4.4e-20 71.9 4.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1674) COesterase PF00135.28 ORY11650.1 - 6e-75 253.1 0.2 1.9e-74 251.4 0.2 1.6 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 ORY11650.1 - 4.8e-06 26.6 0.0 4.4e-05 23.4 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 ORY11650.1 - 0.046 13.2 0.0 0.083 12.3 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family DOCK_N PF16172.5 ORY11651.1 - 1.3e-112 376.4 0.0 1.3e-112 376.4 0.0 1.8 2 0 0 2 2 2 1 DOCK N-terminus DHR-2 PF06920.13 ORY11651.1 - 2e-40 138.9 3.8 7.5e-40 137.1 3.8 1.8 1 1 0 1 1 1 1 Dock homology region 2 DOCK-C2 PF14429.6 ORY11651.1 - 5.8e-35 120.9 0.0 1.4e-34 119.6 0.0 1.7 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins SH3_1 PF00018.28 ORY11651.1 - 0.0035 16.9 0.0 0.0078 15.8 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 ORY11651.1 - 0.0093 15.8 0.0 0.023 14.6 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain NUC173 PF08161.12 ORY11652.1 - 1.3e-80 269.9 1.2 2.2e-75 252.8 0.0 3.3 3 0 0 3 3 3 2 NUC173 domain Cnd1 PF12717.7 ORY11652.1 - 0.0054 16.8 0.2 0.21 11.6 0.1 3.1 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 ORY11652.1 - 0.0058 16.8 0.7 7.7 7.1 0.0 4.0 4 0 0 4 4 4 1 HEAT repeat HEAT_2 PF13646.6 ORY11652.1 - 0.03 14.7 6.5 0.34 11.3 0.2 4.6 3 1 1 4 4 4 0 HEAT repeats ORC5_C PF14630.6 ORY11652.1 - 0.039 13.5 0.1 0.11 12.0 0.1 1.7 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 5 C-terminus DUF3385 PF11865.8 ORY11652.1 - 0.042 13.8 0.8 17 5.3 0.0 4.5 4 1 1 5 5 5 0 Domain of unknown function (DUF3385) Vac14_Fab1_bd PF12755.7 ORY11652.1 - 0.14 12.8 0.0 11 6.7 0.0 3.7 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region MMS19_C PF12460.8 ORY11652.1 - 0.46 9.5 7.4 0.21 10.7 0.8 3.4 3 2 1 4 4 4 0 RNAPII transcription regulator C-terminal MRG PF05712.13 ORY11653.1 - 1.9e-51 174.2 0.5 2.8e-51 173.7 0.5 1.2 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.8 ORY11653.1 - 3.5e-08 33.2 0.8 7.6e-08 32.1 0.8 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo PF00385.24 ORY11653.1 - 0.0052 16.7 0.9 0.012 15.5 0.9 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Cnl2_NKP2 PF09447.10 ORY11654.1 - 5.3e-23 80.9 0.1 2.8e-22 78.6 0.0 2.1 2 1 1 3 3 3 1 Cnl2/NKP2 family protein Syntaxin-6_N PF09177.11 ORY11654.1 - 0.019 15.5 0.2 0.18 12.4 0.1 2.4 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Phage_TAC_12 PF12363.8 ORY11654.1 - 0.069 13.6 0.0 0.44 11.0 0.0 2.0 2 0 0 2 2 2 0 Phage tail assembly chaperone protein, TAC Apolipoprotein PF01442.18 ORY11654.1 - 0.08 12.8 2.3 0.11 12.4 2.3 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain HLH PF00010.26 ORY11655.1 - 7e-08 32.3 0.1 2.7e-07 30.5 0.1 2.0 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Herpes_DNAp_acc PF04929.12 ORY11655.1 - 0.14 11.1 3.5 0.25 10.3 3.5 1.3 1 0 0 1 1 1 0 Herpes DNA replication accessory factor CDC45 PF02724.14 ORY11655.1 - 9.5 4.4 9.8 15 3.8 9.8 1.2 1 0 0 1 1 1 0 CDC45-like protein SKG6 PF08693.10 ORY11657.1 - 9.2e-05 21.8 0.0 0.00019 20.7 0.0 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Podoplanin PF05808.11 ORY11657.1 - 0.16 12.0 3.2 0.35 11.0 3.2 1.4 1 0 0 1 1 1 0 Podoplanin Alpha_GJ PF03229.13 ORY11657.1 - 0.24 12.0 14.4 1 10.0 14.4 2.0 1 1 0 1 1 1 0 Alphavirus glycoprotein J Dickkopf_N PF04706.12 ORY11658.1 - 0.021 15.3 1.6 0.021 15.3 1.6 4.5 3 1 1 4 4 4 0 Dickkopf N-terminal cysteine-rich region SprT-like PF10263.9 ORY11658.1 - 0.081 12.8 0.1 0.21 11.5 0.1 1.6 1 0 0 1 1 1 0 SprT-like family Clat_adaptor_s PF01217.20 ORY11659.1 - 8.1e-43 145.8 0.0 8.8e-30 103.5 0.0 2.0 2 0 0 2 2 2 2 Clathrin adaptor complex small chain Frataxin_Cyay PF01491.16 ORY11660.1 - 1.5e-34 118.3 0.0 1.8e-34 118.0 0.0 1.1 1 0 0 1 1 1 1 Frataxin-like domain HalOD1 PF18545.1 ORY11660.1 - 0.022 15.0 0.1 0.035 14.4 0.1 1.4 1 0 0 1 1 1 0 Halobacterial output domain 1 Tudor-knot PF11717.8 ORY11660.1 - 0.19 11.6 0.7 0.44 10.5 0.2 1.9 2 0 0 2 2 2 0 RNA binding activity-knot of a chromodomain zf-CSL PF05207.13 ORY11661.1 - 1.1e-18 66.7 1.9 1.3e-18 66.4 1.9 1.1 1 0 0 1 1 1 1 CSL zinc finger zf-TFIIB PF13453.6 ORY11661.1 - 0.33 10.3 4.0 2.7 7.4 1.5 2.3 2 0 0 2 2 2 0 Transcription factor zinc-finger Sec6 PF06046.13 ORY11662.1 - 7e-159 529.8 7.5 7e-159 529.8 7.5 1.7 2 0 0 2 2 2 1 Exocyst complex component Sec6 Noelin-1 PF12308.8 ORY11662.1 - 0.034 14.1 2.6 2.2 8.3 0.4 3.1 2 0 0 2 2 2 0 Neurogenesis glycoprotein APG6_N PF17675.1 ORY11662.1 - 1.5 9.3 11.7 1.5 9.4 4.8 2.7 2 0 0 2 2 2 0 Apg6 coiled-coil region AAA_13 PF13166.6 ORY11662.1 - 1.6 7.3 8.2 1.9 7.0 6.9 1.7 1 1 1 2 2 2 0 AAA domain KxDL PF10241.9 ORY11662.1 - 4.8 7.5 6.0 2.7 8.3 1.3 3.1 3 1 0 3 3 3 0 Uncharacterized conserved protein Mod_r PF07200.13 ORY11662.1 - 5.6 7.1 11.8 7.6 6.6 5.3 2.9 2 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein AAA_18 PF13238.6 ORY11663.1 - 1e-05 26.1 0.0 0.00016 22.2 0.0 2.2 1 1 0 1 1 1 1 AAA domain PRK PF00485.18 ORY11663.1 - 0.0011 18.7 0.0 0.015 15.1 0.0 2.1 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family CPT PF07931.12 ORY11663.1 - 0.0055 16.6 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein Cytidylate_kin PF02224.18 ORY11663.1 - 0.0093 15.7 0.1 0.18 11.5 0.0 2.2 2 0 0 2 2 2 1 Cytidylate kinase dNK PF01712.19 ORY11663.1 - 0.021 14.7 0.0 0.1 12.4 0.0 1.9 1 1 0 1 1 1 0 Deoxynucleoside kinase AAA_28 PF13521.6 ORY11663.1 - 0.05 13.8 0.0 0.22 11.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 ORY11663.1 - 0.056 13.8 0.0 0.088 13.2 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 ORY11663.1 - 0.16 12.1 0.1 0.78 9.9 0.1 2.0 1 1 0 1 1 1 0 AAA domain DUF1741 PF08427.10 ORY11664.1 - 2.5e-83 279.3 0.1 7.7e-83 277.7 0.1 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF1741) HMG_box PF00505.19 ORY11682.1 - 1.8e-09 37.8 1.4 1.8e-09 37.8 1.4 2.0 2 0 0 2 2 2 1 HMG (high mobility group) box SAM_1 PF00536.30 ORY11682.1 - 6.5e-07 29.7 0.0 1.7e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 ORY11682.1 - 0.00019 21.5 0.0 0.00045 20.3 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) HMG_box_2 PF09011.10 ORY11682.1 - 0.0079 16.8 1.6 0.022 15.4 1.6 1.8 1 0 0 1 1 1 1 HMG-box domain DUF4805 PF16063.5 ORY11682.1 - 0.016 14.5 1.3 0.031 13.6 1.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4805) FAM60A PF15396.6 ORY11682.1 - 0.039 14.0 0.8 0.082 12.9 0.8 1.4 1 0 0 1 1 1 0 Protein Family FAM60A YIEGIA PF14045.6 ORY11684.1 - 0.081 11.8 0.3 0.099 11.5 0.3 1.2 1 0 0 1 1 1 0 YIEGIA protein Peptidase_M54 PF07998.11 ORY11685.1 - 3.6e-10 40.2 0.0 1.5e-09 38.1 0.1 1.8 2 0 0 2 2 2 1 Peptidase family M54 Metallopep PF12044.8 ORY11685.1 - 0.16 10.5 0.8 0.28 9.7 0.8 1.3 1 0 0 1 1 1 0 Putative peptidase family MFS_1 PF07690.16 ORY11686.1 - 6.3e-32 110.9 24.3 6.3e-32 110.9 24.3 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY11686.1 - 4.9e-13 48.7 3.2 4.9e-13 48.7 3.2 1.6 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 ORY11686.1 - 5.6e-05 21.8 2.0 8.2e-05 21.2 2.0 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Glyco_transf_25 PF01755.17 ORY11687.1 - 3.3e-13 50.0 0.0 3.3e-11 43.4 0.0 2.2 2 0 0 2 2 2 2 Glycosyltransferase family 25 (LPS biosynthesis protein) FHA PF00498.26 ORY11689.1 - 3e-13 49.9 0.1 5e-13 49.2 0.1 1.4 1 0 0 1 1 1 1 FHA domain TauE PF01925.19 ORY11689.1 - 0.13 11.9 0.7 0.17 11.5 0.7 1.1 1 0 0 1 1 1 0 Sulfite exporter TauE/SafE RNA_pol_Rpb1_1 PF04997.12 ORY11690.1 - 2.1e-80 270.4 0.1 3.5e-80 269.7 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 ORY11690.1 - 4.8e-80 268.8 0.4 7.2e-80 268.2 0.4 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 ORY11690.1 - 1.8e-69 233.2 0.0 3.4e-69 232.3 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 ORY11690.1 - 1.4e-35 122.5 0.0 5.4e-35 120.6 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 ORY11690.1 - 5.9e-26 90.5 0.0 2.2e-25 88.7 0.0 2.1 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 zf-tcix PF14952.6 ORY11690.1 - 0.1 12.2 2.1 0.28 10.8 2.1 1.7 1 0 0 1 1 1 0 Putative treble-clef, zinc-finger, Zn-binding Melibiase_2 PF16499.5 ORY11691.1 - 1.8e-67 227.5 3.6 2.9e-67 226.8 3.6 1.3 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 ORY11691.1 - 8.4e-10 38.6 0.3 2.4e-08 33.9 0.1 2.5 2 0 0 2 2 2 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 ORY11691.1 - 0.00013 21.0 0.0 0.00023 20.3 0.0 1.3 1 0 0 1 1 1 1 Melibiase Big_3_5 PF16640.5 ORY11691.1 - 0.077 13.2 0.7 0.21 11.8 0.7 1.7 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 3) Pyridox_ox_2 PF12900.7 ORY11692.1 - 5.2e-35 120.5 0.0 7.1e-35 120.1 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase G6PD_C PF02781.16 ORY11692.1 - 0.14 11.4 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 Glucose-6-phosphate dehydrogenase, C-terminal domain Tannase PF07519.11 ORY11693.1 - 1e-95 321.4 1.2 1.2e-95 321.1 1.2 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Hydrolase_4 PF12146.8 ORY11693.1 - 0.00026 20.3 0.0 0.0048 16.2 0.0 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ORY11693.1 - 0.0015 18.2 0.4 0.034 13.8 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold TRI12 PF06609.13 ORY11695.1 - 1.3e-62 212.1 33.4 1.7e-62 211.7 33.4 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 ORY11695.1 - 2.5e-16 59.6 68.5 2.5e-16 59.6 68.5 3.6 1 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY11695.1 - 5.9e-08 32.0 13.7 5.9e-08 32.0 13.7 4.2 1 1 3 5 5 5 1 Sugar (and other) transporter TNFR_16_TM PF18422.1 ORY11695.1 - 0.062 13.3 1.6 0.24 11.4 1.6 2.0 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain Beta_helix PF13229.6 ORY11696.1 - 0.0092 15.8 11.7 0.0092 15.8 11.7 4.0 2 2 0 3 3 3 3 Right handed beta helix region Glyco_hydro_3_C PF01915.22 ORY11697.1 - 3.7e-35 121.8 0.0 6.7e-35 120.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 ORY11697.1 - 3.3e-30 105.5 0.0 5.1e-30 104.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 ORY11697.1 - 6.4e-05 23.0 0.0 0.00018 21.5 0.0 1.7 2 0 0 2 2 2 1 Fibronectin type III-like domain Pkinase PF00069.25 ORY11699.1 - 4e-64 216.5 0.0 5.3e-64 216.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY11699.1 - 1.9e-37 129.0 0.0 2.6e-37 128.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORY11699.1 - 0.0019 17.0 0.0 0.0031 16.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 ORY11699.1 - 0.0024 16.9 0.0 0.0055 15.7 0.0 1.5 2 0 0 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 ORY11699.1 - 0.0056 16.0 0.0 0.018 14.4 0.0 1.8 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 ORY11699.1 - 0.0083 16.1 0.0 0.019 14.9 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 ORY11699.1 - 0.028 14.0 0.1 0.094 12.3 0.0 1.8 2 0 0 2 2 2 0 RIO1 family SH2_2 PF14633.6 ORY11700.1 - 5.3e-83 277.7 0.0 5.3e-83 277.7 0.0 2.0 2 0 0 2 2 2 1 SH2 domain YqgF PF14639.6 ORY11700.1 - 4.9e-32 110.8 0.0 2.8e-30 105.1 0.0 2.7 2 0 0 2 2 2 1 Holliday-junction resolvase-like of SPT6 HTH_44 PF14641.6 ORY11700.1 - 1.3e-31 109.4 0.5 3.4e-31 108.1 0.5 1.7 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 HHH_7 PF14635.6 ORY11700.1 - 2e-28 98.8 0.0 4.8e-28 97.6 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif SPT6_acidic PF14632.6 ORY11700.1 - 2.7e-17 63.1 26.3 2.7e-17 63.1 26.3 5.0 6 0 0 6 6 6 1 Acidic N-terminal SPT6 HHH_9 PF17674.1 ORY11700.1 - 5.5e-07 30.4 1.3 9.4e-06 26.4 0.7 3.5 2 1 0 2 2 2 1 HHH domain SH2 PF00017.24 ORY11700.1 - 4.3e-06 26.7 0.0 9.2e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 SH2 domain Tex_YqgF PF16921.5 ORY11700.1 - 0.0027 18.1 0.0 0.0068 16.9 0.0 1.7 1 0 0 1 1 1 1 Tex protein YqgF-like domain HHH_3 PF12836.7 ORY11700.1 - 0.006 16.8 0.0 0.035 14.4 0.0 2.3 1 1 0 1 1 1 1 Helix-hairpin-helix motif MRI PF15325.6 ORY11700.1 - 5.5 8.1 16.2 0.028 15.5 4.2 2.9 1 1 1 2 2 2 0 Modulator of retrovirus infection Exo_endo_phos PF03372.23 ORY11701.1 - 5.8e-11 42.3 0.0 8.8e-11 41.8 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF1168 PF06658.12 ORY11703.1 - 1.4e-39 135.0 9.7 1.4e-39 135.0 9.7 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1168) DUF572 PF04502.13 ORY11703.1 - 0.026 14.2 10.0 0.038 13.6 10.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Lyase_catalyt PF09093.11 ORY11703.1 - 0.03 13.5 0.0 0.04 13.1 0.0 1.2 1 0 0 1 1 1 0 Lyase, catalytic RNA_pol_Rpc82 PF05645.13 ORY11703.1 - 0.23 11.2 5.5 0.34 10.6 5.5 1.2 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 LRIF1 PF15741.5 ORY11703.1 - 0.31 9.5 3.4 0.36 9.3 3.4 1.1 1 0 0 1 1 1 0 Ligand-dependent nuclear receptor-interacting factor 1 His_Phos_1 PF00300.22 ORY11704.1 - 1.3e-27 96.8 0.0 3e-27 95.6 0.0 1.6 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.22 ORY11704.1 - 0.033 13.6 0.0 0.055 12.8 0.0 1.3 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) P5-ATPase PF12409.8 ORY11704.1 - 0.095 12.8 0.0 0.26 11.4 0.0 1.8 1 0 0 1 1 1 0 P5-type ATPase cation transporter MGTL PF17059.5 ORY11704.1 - 0.13 12.1 0.5 0.41 10.5 0.5 1.9 1 0 0 1 1 1 0 MgtA leader peptide AA_permease_2 PF13520.6 ORY11705.1 - 5.3e-53 180.4 56.9 6.3e-53 180.1 56.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ORY11705.1 - 2.8e-24 85.6 47.0 3.9e-24 85.1 47.0 1.1 1 0 0 1 1 1 1 Amino acid permease MFS_1 PF07690.16 ORY11706.1 - 5e-41 140.8 48.4 8.1e-41 140.1 43.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY11706.1 - 1.2e-12 47.5 8.4 1.2e-12 47.5 8.4 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter But2 PF09792.9 ORY11707.1 - 2.1e-39 135.2 0.0 4.8e-39 134.0 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin 3 binding protein But2 C-terminal domain NAD_binding_10 PF13460.6 ORY11709.1 - 1e-19 71.2 0.0 1.4e-19 70.7 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 ORY11709.1 - 1.5e-17 64.0 0.1 2e-17 63.5 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.24 ORY11709.1 - 4.8e-05 23.8 0.0 9.4e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 ORY11709.1 - 0.00065 19.8 0.6 0.001 19.1 0.0 1.6 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase DapB_N PF01113.20 ORY11709.1 - 0.00083 19.5 0.1 0.0021 18.1 0.1 1.7 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus NAD_binding_4 PF07993.12 ORY11709.1 - 0.0069 15.6 0.0 0.01 15.0 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 ORY11709.1 - 0.052 13.0 0.0 0.12 11.8 0.0 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family PARG_cat PF05028.14 ORY11711.1 - 1.8e-21 76.8 0.0 2.6e-21 76.3 0.0 1.1 1 0 0 1 1 1 1 Poly (ADP-ribose) glycohydrolase (PARG) DUF4880 PF16220.5 ORY11711.1 - 0.041 13.8 0.8 0.11 12.4 0.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4880) Amidohydro_1 PF01979.20 ORY11712.1 - 1.6e-18 67.2 0.8 9.6e-18 64.6 0.8 2.1 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 ORY11712.1 - 1.7e-14 54.2 0.8 5.4e-09 36.0 0.1 2.4 2 1 0 2 2 2 2 Amidohydrolase family APG12 PF04110.13 ORY11714.1 - 0.13 12.7 0.0 0.46 10.9 0.0 1.9 1 0 0 1 1 1 0 Ubiquitin-like autophagy protein Apg12 Condensation PF00668.20 ORY11714.1 - 0.19 10.3 0.2 0.93 8.1 0.0 1.8 2 0 0 2 2 2 0 Condensation domain HATPase_c PF02518.26 ORY11716.1 - 2.7e-22 79.4 0.0 6e-22 78.3 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 ORY11716.1 - 1.3e-12 47.5 0.0 3.9e-12 46.0 0.0 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain DUF4567 PF15131.6 ORY11716.1 - 0.072 13.1 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4567) GAF_2 PF13185.6 ORY11716.1 - 0.13 12.6 0.1 0.6 10.4 0.0 2.2 2 1 0 2 2 2 0 GAF domain Response_reg PF00072.24 ORY11717.1 - 2.6e-20 72.7 0.0 7.9e-20 71.1 0.0 1.7 1 1 0 1 1 1 1 Response regulator receiver domain Dscam_C PF12355.8 ORY11720.1 - 0.097 13.6 0.4 0.14 13.1 0.4 1.2 1 0 0 1 1 1 0 Down syndrome cell adhesion molecule C terminal DUF3602 PF12223.8 ORY11721.1 - 1e-22 80.5 7.6 1.8e-18 66.9 0.3 2.8 2 1 1 3 3 3 2 Protein of unknown function (DUF3602) PNPase_C PF12111.8 ORY11721.1 - 0.16 11.4 9.9 0.28 10.6 1.6 3.5 3 0 0 3 3 3 0 Polyribonucleotide phosphorylase C terminal Actin PF00022.19 ORY11722.1 - 3.3e-126 421.2 0.0 1.6e-125 418.9 0.0 1.8 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 ORY11722.1 - 0.00018 20.5 0.0 0.0018 17.2 0.0 2.4 1 1 0 1 1 1 1 MreB/Mbl protein DUF4692 PF15763.5 ORY11722.1 - 0.14 12.6 0.0 0.24 11.9 0.0 1.3 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) MFS_1 PF07690.16 ORY11724.1 - 2.3e-43 148.5 64.1 2.3e-43 148.5 64.1 3.2 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 ORY11724.1 - 2.9e-17 62.4 29.8 3.8e-17 62.0 29.8 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2919 PF11143.8 ORY11724.1 - 0.0018 18.6 1.4 0.0092 16.3 1.4 2.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2919) ADH_N PF08240.12 ORY11725.1 - 3e-23 81.8 0.3 5.5e-23 80.9 0.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORY11725.1 - 2.8e-14 53.2 0.0 4.8e-14 52.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 ORY11725.1 - 0.00031 20.1 0.1 0.00054 19.4 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 ORY11725.1 - 0.0004 19.7 0.3 0.0012 18.2 0.3 1.7 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain adh_short PF00106.25 ORY11725.1 - 0.077 12.4 0.3 2.9 7.3 0.0 2.2 2 0 0 2 2 2 0 short chain dehydrogenase NAD_binding_2 PF03446.15 ORY11725.1 - 0.097 12.8 0.3 0.2 11.8 0.1 1.6 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 ORY11725.1 - 0.12 12.3 0.2 0.21 11.5 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TRP PF06011.12 ORY11728.1 - 2e-165 550.7 26.8 2.4e-165 550.4 26.8 1.0 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 ORY11728.1 - 9.4e-39 133.0 0.2 1.5e-38 132.3 0.2 1.3 1 0 0 1 1 1 1 ML-like domain E1_DerP2_DerF2 PF02221.15 ORY11728.1 - 9.7e-05 22.8 0.0 0.00016 22.1 0.0 1.3 1 0 0 1 1 1 1 ML domain Pkinase PF00069.25 ORY11731.1 - 1.2e-12 47.8 0.0 6.8e-12 45.3 0.0 2.0 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY11731.1 - 0.0049 16.2 0.0 0.024 13.9 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 ORY11731.1 - 0.26 10.6 0.0 0.44 9.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-RING_UBOX PF13445.6 ORY11732.1 - 1.2e-09 38.0 2.9 1.9e-09 37.4 2.0 1.8 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 ORY11732.1 - 3.2e-09 36.5 0.7 6e-09 35.6 0.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORY11732.1 - 3.7e-07 30.4 2.2 7.5e-07 29.4 2.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 ORY11732.1 - 1.6e-06 27.8 1.7 1.6e-06 27.8 1.7 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 ORY11732.1 - 5.3e-05 23.3 1.7 9.1e-05 22.5 1.7 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 ORY11732.1 - 0.00017 21.4 1.9 0.0003 20.6 1.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORY11732.1 - 0.00032 20.6 1.8 0.00057 19.8 1.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_6 PF14835.6 ORY11732.1 - 0.0014 18.4 3.5 0.0033 17.3 3.5 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 ORY11732.1 - 0.0023 18.2 1.1 0.0055 17.0 1.1 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-Nse PF11789.8 ORY11732.1 - 0.0044 16.8 0.0 0.0086 15.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_11 PF17123.5 ORY11732.1 - 0.0097 15.6 3.3 0.022 14.5 3.3 1.7 1 0 0 1 1 1 1 RING-like zinc finger Prok-RING_4 PF14447.6 ORY11732.1 - 0.025 14.5 3.8 0.051 13.4 3.8 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 ORY11732.1 - 0.36 11.0 2.4 0.71 10.0 2.4 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 Cpn60_TCP1 PF00118.24 ORY11733.1 - 3.2e-171 570.3 2.0 3.7e-171 570.1 2.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Solute_trans_a PF03619.16 ORY11735.1 - 1.3e-58 198.7 13.9 1.6e-58 198.4 13.9 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Col_cuticle_N PF01484.17 ORY11735.1 - 0.063 13.3 0.8 0.063 13.3 0.8 3.1 5 0 0 5 5 5 0 Nematode cuticle collagen N-terminal domain MerC PF03203.14 ORY11735.1 - 5.9 7.4 14.6 2.9e+02 1.9 14.6 2.3 1 1 0 1 1 1 0 MerC mercury resistance protein Sulfatase PF00884.23 ORY11737.1 - 2.2e-59 201.4 0.1 3.1e-59 200.9 0.1 1.2 1 0 0 1 1 1 1 Sulfatase DUF4976 PF16347.5 ORY11737.1 - 0.0091 16.2 0.0 0.023 14.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4976) MFS_1 PF07690.16 ORY11738.1 - 1.2e-40 139.5 42.8 2.5e-40 138.5 42.8 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY11738.1 - 1e-06 27.9 10.8 1e-06 27.9 10.8 3.0 3 1 0 3 3 3 2 Sugar (and other) transporter OATP PF03137.20 ORY11738.1 - 0.2 9.9 8.5 0.55 8.5 1.2 2.3 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family P5-ATPase PF12409.8 ORY11738.1 - 0.33 11.1 1.4 0.64 10.1 1.4 1.4 1 0 0 1 1 1 0 P5-type ATPase cation transporter Fungal_lectin PF07938.12 ORY11739.1 - 1.9e-15 57.0 4.1 1.8e-11 44.0 0.4 2.8 2 1 0 2 2 2 2 Fungal fucose-specific lectin Rick_17kDa_Anti PF05433.15 ORY11739.1 - 0.0058 16.5 1.6 0.0058 16.5 1.6 3.1 3 0 0 3 3 3 1 Glycine zipper 2TM domain zf-C2H2_4 PF13894.6 ORY11740.1 - 5.5 8.1 13.5 6.1 8.0 0.3 3.9 4 0 0 4 4 4 0 C2H2-type zinc finger FAM76 PF16046.5 ORY11742.1 - 0.00022 20.7 2.4 0.00022 20.7 2.4 1.6 2 0 0 2 2 2 1 FAM76 protein bZIP_1 PF00170.21 ORY11742.1 - 0.001 19.1 3.7 0.001 19.1 3.7 2.8 3 0 0 3 3 2 1 bZIP transcription factor ABC_tran_CTD PF16326.5 ORY11742.1 - 0.0064 16.7 9.0 0.28 11.5 0.9 2.5 1 1 1 2 2 2 2 ABC transporter C-terminal domain Tropomyosin PF00261.20 ORY11742.1 - 0.011 15.1 13.5 0.11 11.9 0.5 2.4 1 1 0 2 2 2 0 Tropomyosin Rho_Binding PF08912.11 ORY11742.1 - 0.012 16.5 12.7 0.55 11.1 1.3 3.0 2 1 1 3 3 3 0 Rho Binding Fez1 PF06818.15 ORY11742.1 - 0.017 15.6 7.6 0.027 14.9 7.6 1.4 1 0 0 1 1 1 0 Fez1 TMCO5 PF14992.6 ORY11742.1 - 0.022 14.3 9.1 0.033 13.8 9.1 1.3 1 0 0 1 1 1 0 TMCO5 family ATG16 PF08614.11 ORY11742.1 - 0.027 14.7 17.8 0.058 13.6 0.2 2.7 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) Tektin PF03148.14 ORY11742.1 - 0.033 13.0 8.7 0.079 11.7 8.7 1.5 1 1 0 1 1 1 0 Tektin family Spectrin PF00435.21 ORY11742.1 - 0.034 14.6 7.5 1.6 9.2 3.9 2.4 1 1 1 2 2 2 0 Spectrin repeat HAP1_N PF04849.13 ORY11742.1 - 0.062 12.5 9.0 0.11 11.7 9.0 1.4 1 0 0 1 1 1 0 HAP1 N-terminal conserved region V_ATPase_I PF01496.19 ORY11742.1 - 0.1 10.5 5.5 0.13 10.1 5.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1192 PF06698.11 ORY11742.1 - 0.19 11.8 3.5 0.27 11.3 0.1 2.6 2 1 1 3 3 2 0 Protein of unknown function (DUF1192) FYVE_2 PF02318.16 ORY11742.1 - 0.24 11.7 4.1 0.56 10.4 4.1 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger DUF4164 PF13747.6 ORY11742.1 - 0.33 11.2 6.8 0.44 10.9 2.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) Wtap PF17098.5 ORY11742.1 - 0.38 10.7 8.0 2.6 8.0 7.6 2.1 1 1 0 1 1 1 0 WTAP/Mum2p family RmuC PF02646.16 ORY11742.1 - 0.47 9.5 8.8 5.9 5.9 5.1 2.2 2 0 0 2 2 2 0 RmuC family Atg14 PF10186.9 ORY11742.1 - 0.7 8.9 7.8 1 8.4 7.8 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TMF_DNA_bd PF12329.8 ORY11742.1 - 0.86 9.6 15.9 8.4 6.5 10.9 2.6 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Occludin_ELL PF07303.13 ORY11742.1 - 0.99 10.2 6.2 5.1 7.9 0.9 2.4 2 0 0 2 2 2 0 Occludin homology domain Jnk-SapK_ap_N PF09744.9 ORY11742.1 - 2.2 8.5 14.9 8.5 6.6 14.5 2.0 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 TSC22 PF01166.18 ORY11742.1 - 2.5 8.5 8.2 3 8.2 1.9 2.9 2 1 1 3 3 3 0 TSC-22/dip/bun family Laps PF10169.9 ORY11742.1 - 2.9 8.5 10.3 0.18 12.4 4.6 1.9 2 1 0 2 2 1 0 Learning-associated protein DUF3450 PF11932.8 ORY11742.1 - 3 7.1 8.6 32 3.7 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Nnf1 PF03980.14 ORY11742.1 - 3.1 8.2 10.5 16 6.0 7.0 3.2 1 1 1 2 2 2 0 Nnf1 DUF4407 PF14362.6 ORY11742.1 - 4.1 6.7 9.5 10 5.4 9.5 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) UPF0242 PF06785.11 ORY11742.1 - 5 7.2 14.0 12 6.0 12.8 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus ZapB PF06005.12 ORY11742.1 - 5.7 7.5 14.8 21 5.7 6.2 2.5 1 1 1 2 2 2 0 Cell division protein ZapB bZIP_2 PF07716.15 ORY11742.1 - 6.4 7.0 12.7 0.2 11.7 2.6 3.1 2 1 2 4 4 4 0 Basic region leucine zipper Glyco_hydro_2_C PF02836.17 ORY11743.1 - 2.3e-104 348.8 0.0 3.2e-104 348.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.17 ORY11743.1 - 1.2e-63 215.0 0.0 1.9e-63 214.3 0.0 1.3 1 0 0 1 1 1 1 Beta galactosidase small chain Glyco_hydro_2_N PF02837.18 ORY11743.1 - 1.6e-17 63.9 0.6 5.5e-14 52.4 0.6 2.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.21 ORY11743.1 - 3.3e-08 34.2 0.0 1.2e-07 32.4 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 2 DUF4981 PF16353.5 ORY11743.1 - 5e-06 26.9 0.2 0.00019 21.8 0.0 2.8 2 1 0 2 2 2 1 Domain of unknown function(DUF4981) Glucosamine_iso PF01182.20 ORY11744.1 - 0.0017 18.2 0.0 0.0019 18.1 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Glucosamine_iso PF01182.20 ORY11745.1 - 0.0071 16.3 0.0 0.01 15.8 0.0 1.3 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Zn_clus PF00172.18 ORY11746.1 - 0.95 9.6 5.7 1.5 9.0 5.7 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Hexokinase_2 PF03727.16 ORY11747.1 - 2.3e-70 236.8 0.2 3.6e-70 236.1 0.0 1.4 2 0 0 2 2 2 1 Hexokinase Hexokinase_1 PF00349.21 ORY11747.1 - 1.4e-65 220.9 0.0 2e-65 220.4 0.0 1.2 1 0 0 1 1 1 1 Hexokinase HU-HIG PF18291.1 ORY11747.1 - 0.023 14.8 0.1 0.048 13.8 0.1 1.4 1 0 0 1 1 1 0 HU domain fused to wHTH, Ig, or Glycine-rich motif Bac_DNA_binding PF00216.21 ORY11747.1 - 0.15 12.3 0.0 0.54 10.5 0.0 1.9 2 0 0 2 2 2 0 Bacterial DNA-binding protein Sugar_tr PF00083.24 ORY11749.1 - 7.8e-08 31.6 0.3 9.4e-08 31.3 0.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY11749.1 - 4.7e-05 22.5 0.5 5.2e-05 22.3 0.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 ORY11749.1 - 0.084 11.4 0.2 0.13 10.8 0.1 1.3 1 1 0 1 1 1 0 MFS/sugar transport protein Sugar_tr PF00083.24 ORY11750.1 - 7e-62 209.8 19.9 7.9e-62 209.6 19.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY11750.1 - 6.6e-14 51.6 37.9 3.7e-12 45.8 20.1 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily 7tm_1 PF00001.21 ORY11750.1 - 0.00085 18.7 1.3 0.00085 18.7 1.3 2.0 2 1 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) Epimerase PF01370.21 ORY11751.1 - 5.9e-14 52.1 0.1 1.4e-07 31.3 0.0 2.9 3 0 0 3 3 3 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 ORY11751.1 - 1.9e-07 31.2 0.0 4.7e-07 29.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 ORY11751.1 - 2.4e-05 24.0 0.0 4.4e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family GDP_Man_Dehyd PF16363.5 ORY11751.1 - 0.00072 19.0 0.3 0.032 13.6 0.0 2.3 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 ORY11751.1 - 0.0013 17.9 1.3 0.0034 16.6 0.2 2.0 1 1 1 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.19 ORY11751.1 - 0.024 13.6 0.0 3.8 6.4 0.0 2.2 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 ORY11751.1 - 0.025 15.0 0.0 0.051 14.0 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DEAD PF00270.29 ORY11752.1 - 7.2e-47 159.4 0.0 1.3e-46 158.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY11752.1 - 3e-25 88.7 0.0 3.6e-24 85.3 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 ORY11752.1 - 2.7e-19 69.1 0.1 2.7e-19 69.1 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4217) ERCC3_RAD25_C PF16203.5 ORY11752.1 - 9e-05 21.8 0.0 0.00022 20.5 0.0 1.6 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 ORY11752.1 - 0.00011 22.3 0.0 0.00026 21.0 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Antigen_Bd37 PF11641.8 ORY11752.1 - 0.047 13.2 0.5 0.086 12.3 0.5 1.3 1 0 0 1 1 1 0 Glycosylphosphatidylinositol-anchored merozoite surface protein Swi5 PF07061.11 ORY11753.1 - 0.16 12.1 0.2 0.74 9.9 0.2 2.1 2 0 0 2 2 2 0 Swi5 Condensation PF00668.20 ORY11754.1 - 0 1264.0 0.0 4.2e-54 183.9 0.0 9.6 9 1 0 9 9 9 9 Condensation domain AMP-binding PF00501.28 ORY11754.1 - 0 1023.3 0.0 1.1e-82 277.9 0.0 4.2 4 0 0 4 4 4 4 AMP-binding enzyme PP-binding PF00550.25 ORY11754.1 - 3.3e-66 219.5 11.4 7e-12 45.5 0.1 8.1 8 0 0 8 8 8 7 Phosphopantetheine attachment site Transferase PF02458.15 ORY11754.1 - 1.1e-09 37.5 0.0 0.00057 18.7 0.0 3.5 3 0 0 3 3 3 3 Transferase family AMP-binding_C PF13193.6 ORY11754.1 - 4.2e-06 27.7 0.0 2.7 9.0 0.0 4.7 4 0 0 4 4 4 2 AMP-binding enzyme C-terminal domain CdiA_C_tRNase PF18664.1 ORY11754.1 - 0.2 11.8 0.2 20 5.4 0.0 2.9 2 0 0 2 2 2 0 CdiA C-terminal tRNase domain AMP-binding PF00501.28 ORY11755.1 - 1.5e-49 168.7 0.0 1.9e-49 168.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ABC_membrane PF00664.23 ORY11757.1 - 2.4e-32 112.7 35.8 7.9e-28 97.9 19.4 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 ORY11757.1 - 5.6e-19 69.0 0.0 1e-18 68.2 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 ORY11757.1 - 0.0023 17.4 0.1 0.066 12.6 0.0 2.3 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA PF00004.29 ORY11757.1 - 0.0035 17.8 0.0 0.0078 16.6 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 ORY11757.1 - 0.0047 16.8 0.0 0.0089 15.9 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 ORY11757.1 - 0.0059 16.9 0.0 0.019 15.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 ORY11757.1 - 0.0078 15.9 0.0 0.017 14.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 ORY11757.1 - 0.01 15.7 0.0 0.023 14.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Adeno_IVa2 PF02456.15 ORY11757.1 - 0.014 14.2 0.0 0.024 13.4 0.0 1.3 1 0 0 1 1 1 0 Adenovirus IVa2 protein AAA_16 PF13191.6 ORY11757.1 - 0.018 15.4 0.0 0.05 14.0 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain RNA_helicase PF00910.22 ORY11757.1 - 0.02 15.2 0.0 0.057 13.8 0.0 1.7 2 0 0 2 2 1 0 RNA helicase Rad17 PF03215.15 ORY11757.1 - 0.027 14.4 0.1 0.056 13.4 0.1 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain T2SSE PF00437.20 ORY11757.1 - 0.044 12.8 0.0 0.075 12.1 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein ATPase_2 PF01637.18 ORY11757.1 - 0.052 13.5 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea NACHT PF05729.12 ORY11757.1 - 0.054 13.4 0.8 0.44 10.4 0.0 2.5 2 0 0 2 2 2 0 NACHT domain AAA_23 PF13476.6 ORY11757.1 - 0.054 14.0 0.0 0.096 13.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 ORY11757.1 - 0.055 12.7 0.0 0.089 12.1 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_7 PF12775.7 ORY11757.1 - 0.062 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Viral_helicase1 PF01443.18 ORY11757.1 - 0.089 12.5 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase cobW PF02492.19 ORY11757.1 - 0.093 12.3 0.3 0.17 11.4 0.3 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 ORY11757.1 - 0.1 12.7 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 ORY11757.1 - 0.11 11.7 0.1 0.32 10.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF815) ABC_ATPase PF09818.9 ORY11757.1 - 0.15 10.9 0.2 0.61 8.8 0.0 2.0 3 0 0 3 3 3 0 Predicted ATPase of the ABC class Dynamin_N PF00350.23 ORY11757.1 - 0.16 12.0 0.0 0.27 11.3 0.0 1.3 1 0 0 1 1 1 0 Dynamin family MMR_HSR1 PF01926.23 ORY11757.1 - 0.18 11.9 0.1 0.38 10.9 0.1 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase TsaE PF02367.17 ORY11757.1 - 0.19 11.7 0.2 0.85 9.6 0.0 2.1 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE An_peroxidase PF03098.15 ORY11777.1 - 2.4e-13 49.5 0.0 1.4e-11 43.7 0.0 2.7 2 1 0 3 3 3 2 Animal haem peroxidase p450 PF00067.22 ORY11777.1 - 0.0032 16.3 0.0 0.0054 15.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 P5CR_dimer PF14748.6 ORY11778.1 - 1.9e-25 89.1 0.5 3.2e-25 88.4 0.5 1.4 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 ORY11778.1 - 0.026 15.1 0.0 0.13 12.8 0.0 2.2 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent PhyH PF05721.13 ORY11779.1 - 7.2e-16 59.1 0.0 1.1e-15 58.5 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) PhyH PF05721.13 ORY11780.1 - 6.1e-22 78.9 0.0 9.8e-22 78.2 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 ORY11780.1 - 0.017 13.9 0.0 0.025 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1479) Antimicrobial12 PF08107.11 ORY11780.1 - 0.067 13.0 1.3 2.7 7.8 0.2 2.6 2 0 0 2 2 2 0 Pleurocidin family TnsE_C PF18623.1 ORY11780.1 - 0.094 12.6 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 TnsE C-terminal domain Xrn1_D3 PF18194.1 ORY11780.1 - 0.1 12.7 0.0 0.29 11.2 0.1 1.7 2 0 0 2 2 2 0 Exoribonuclease 1 Domain-3 NmrA PF05368.13 ORY11781.1 - 1.6e-12 47.5 0.0 3.4e-12 46.4 0.0 1.5 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ORY11781.1 - 9.6e-12 45.2 0.2 3.2e-11 43.5 0.1 1.9 2 1 0 2 2 2 1 NAD(P)H-binding KR PF08659.10 ORY11781.1 - 3.4e-06 27.1 0.4 5.6e-06 26.4 0.4 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ORY11781.1 - 0.0001 21.9 0.6 0.00018 21.0 0.2 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 ORY11781.1 - 0.0014 18.9 0.2 0.0024 18.1 0.2 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain adh_short PF00106.25 ORY11781.1 - 0.002 17.6 0.3 0.003 17.0 0.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase CbiJ PF02571.14 ORY11781.1 - 0.0039 16.7 0.2 0.0064 16.0 0.2 1.3 1 0 0 1 1 1 1 Precorrin-6x reductase CbiJ/CobK PglD_N PF17836.1 ORY11781.1 - 0.032 14.9 0.0 0.069 13.8 0.0 1.6 1 0 0 1 1 1 0 PglD N-terminal domain Shikimate_DH PF01488.20 ORY11781.1 - 0.048 13.7 0.3 0.09 12.8 0.3 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase RmlD_sub_bind PF04321.17 ORY11781.1 - 0.077 12.1 0.3 0.17 10.9 0.2 1.6 2 0 0 2 2 2 0 RmlD substrate binding domain CUE PF02845.16 ORY11781.1 - 0.16 11.7 0.3 14 5.5 0.1 2.4 2 0 0 2 2 2 0 CUE domain NAD_binding_10 PF13460.6 ORY11782.1 - 4.3e-05 23.5 0.0 6.8e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding AMP-binding PF00501.28 ORY11783.1 - 1.2e-92 310.8 0.0 1.9e-92 310.1 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.26 ORY11783.1 - 8.1e-86 287.7 0.1 1.5e-85 286.9 0.1 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 ORY11783.1 - 1.4e-53 182.5 0.0 2.1e-53 181.9 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.10 ORY11783.1 - 1.6e-53 181.3 0.0 2.8e-52 177.2 0.0 2.6 3 0 0 3 3 3 1 KR domain NAD_binding_4 PF07993.12 ORY11783.1 - 5.4e-45 153.6 0.0 3.2e-44 151.0 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein Ketoacyl-synt_C PF02801.22 ORY11783.1 - 1.5e-40 137.9 0.1 3.7e-40 136.6 0.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.25 ORY11783.1 - 9.7e-22 77.1 0.1 3e-12 46.7 0.0 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site KAsynt_C_assoc PF16197.5 ORY11783.1 - 1.3e-15 57.8 0.1 1.9e-14 54.0 0.0 2.6 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension AMP-binding_C PF13193.6 ORY11783.1 - 3.5e-09 37.5 0.1 1e-08 36.0 0.1 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Epimerase PF01370.21 ORY11783.1 - 4.3e-09 36.2 0.0 7.1e-06 25.7 0.0 2.4 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family adh_short PF00106.25 ORY11783.1 - 1.8e-07 30.8 0.0 2e-05 24.1 0.0 2.4 2 0 0 2 2 2 1 short chain dehydrogenase GDP_Man_Dehyd PF16363.5 ORY11783.1 - 3.7e-06 26.6 0.0 0.0015 18.0 0.0 2.3 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase Thiolase_N PF00108.23 ORY11783.1 - 2.7e-05 23.6 0.1 6.4e-05 22.4 0.1 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain 3Beta_HSD PF01073.19 ORY11783.1 - 0.0001 21.4 0.0 0.38 9.7 0.0 2.6 2 1 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 ORY11783.1 - 0.00025 20.3 0.0 0.2 10.8 0.0 2.5 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein NmrA PF05368.13 ORY11783.1 - 0.19 11.3 1.1 0.94 9.0 0.0 2.5 3 0 0 3 3 3 0 NmrA-like family Pkinase PF00069.25 ORY11784.1 - 4.4e-44 150.8 0.0 6.7e-44 150.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY11784.1 - 2e-26 92.8 0.0 1.8e-25 89.7 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Sacchrp_dh_NADP PF03435.18 ORY11786.1 - 2.2e-16 60.3 0.0 4.1e-16 59.4 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 ORY11786.1 - 0.12 12.8 0.1 0.27 11.7 0.0 1.7 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Zn_clus PF00172.18 ORY11787.1 - 8e-08 32.3 10.1 8e-08 32.3 10.1 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.26 ORY11787.1 - 0.0014 19.0 1.5 0.0014 19.0 1.5 2.2 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-met PF12874.7 ORY11787.1 - 0.041 14.3 1.1 0.091 13.2 1.1 1.6 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 ORY11787.1 - 6.2 6.7 9.0 0.13 12.0 1.6 2.2 2 0 0 2 2 2 0 zinc-finger C2H2-type Glyoxalase_6 PF18029.1 ORY11788.1 - 0.01 16.6 0.0 0.013 16.2 0.0 1.2 1 0 0 1 1 1 0 Glyoxalase-like domain DUF2613 PF11021.8 ORY11789.1 - 0.012 15.7 0.9 0.012 15.7 0.9 2.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2613) DUF2427 PF10348.9 ORY11789.1 - 0.067 13.0 0.0 0.088 12.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2427) TMEM154 PF15102.6 ORY11789.1 - 0.17 11.8 0.0 0.21 11.5 0.0 1.1 1 0 0 1 1 1 0 TMEM154 protein family MSA-2c PF12238.8 ORY11789.1 - 3.3 7.7 4.6 4.5 7.2 4.6 1.1 1 0 0 1 1 1 0 Merozoite surface antigen 2c LCAT PF02450.15 ORY11790.1 - 8.7e-107 357.7 0.1 1e-106 357.4 0.1 1.0 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF1749 PF08538.10 ORY11790.1 - 0.029 13.5 0.0 0.046 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Tobravirus_2B PF05271.11 ORY11790.1 - 0.12 12.3 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 Tobravirus 2B protein Lipase_2 PF01674.18 ORY11790.1 - 0.14 11.7 0.1 0.3 10.6 0.1 1.5 1 0 0 1 1 1 0 Lipase (class 2) Acetyltransf_1 PF00583.25 ORY11791.1 - 1.5e-17 63.9 0.0 2.1e-17 63.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 ORY11791.1 - 2.4e-10 40.3 0.0 3.6e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 ORY11791.1 - 2.6e-10 40.3 0.0 3.9e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ORY11791.1 - 1.2e-09 38.4 0.0 1.9e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 ORY11791.1 - 1.5e-08 35.4 0.0 1.7e-08 35.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 ORY11791.1 - 1.5e-05 24.7 0.0 2.1e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 ORY11791.1 - 5.6e-05 23.2 0.0 0.0001 22.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 ORY11791.1 - 0.0017 18.4 0.0 0.0036 17.4 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.7 ORY11791.1 - 0.0043 17.2 0.0 0.0057 16.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 ORY11791.1 - 0.019 14.6 0.0 0.029 14.0 0.0 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase p450 PF00067.22 ORY11792.1 - 7.3e-54 183.2 0.0 8.4e-54 183.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Cnd1_N PF12922.7 ORY11793.1 - 4.5e-60 202.3 0.8 4.5e-60 202.3 0.8 2.2 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1, N-term Cnd1 PF12717.7 ORY11793.1 - 2e-48 164.5 6.9 2e-43 148.2 0.0 5.0 4 1 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 ORY11793.1 - 2.1e-10 39.9 8.4 0.11 12.8 0.0 8.1 8 1 1 9 9 9 3 HEAT repeat HEAT_2 PF13646.6 ORY11793.1 - 2.6e-07 31.0 11.3 0.014 15.8 0.0 6.2 5 2 0 5 5 5 2 HEAT repeats HEAT_EZ PF13513.6 ORY11793.1 - 5e-05 23.7 7.7 4.3 8.0 0.0 6.5 6 0 0 6 6 6 2 HEAT-like repeat RTP1_C1 PF10363.9 ORY11793.1 - 0.0055 16.9 0.4 8.2 6.7 0.0 4.2 3 1 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 Cnd3 PF12719.7 ORY11793.1 - 0.0066 15.7 0.9 0.0066 15.7 0.9 4.3 4 0 0 4 4 4 1 Nuclear condensing complex subunits, C-term domain Cohesin_HEAT PF12765.7 ORY11793.1 - 0.011 16.1 1.1 7.4 7.0 0.5 4.8 5 0 0 5 5 5 0 HEAT repeat associated with sister chromatid cohesion Peptidase_M16 PF00675.20 ORY11793.1 - 0.49 10.4 2.4 1.3 9.0 0.0 2.8 3 0 0 3 3 3 0 Insulinase (Peptidase family M16) Pkinase PF00069.25 ORY11794.1 - 1.2e-41 142.9 0.0 6e-38 130.7 0.0 3.1 1 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORY11794.1 - 1.7e-09 37.4 0.0 5.3e-07 29.2 0.0 2.8 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORY11794.1 - 0.0039 16.0 0.0 0.0091 14.8 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 ORY11794.1 - 0.0057 16.6 0.1 0.094 12.6 0.0 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 ORY11794.1 - 0.056 12.8 0.1 0.16 11.3 0.1 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_S17 PF00366.20 ORY11795.1 - 1e-15 57.6 0.2 2.3e-15 56.5 0.2 1.6 1 0 0 1 1 1 1 Ribosomal protein S17 DnaJ_C PF01556.18 ORY11796.1 - 4.8e-26 91.6 0.0 6.5e-26 91.2 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 ORY11796.1 - 1.2e-25 89.4 2.0 2e-25 88.7 2.0 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 ORY11796.1 - 2.1e-14 53.6 16.5 3.4e-14 53.0 16.5 1.3 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 ORY11796.1 - 0.00011 22.0 8.5 0.072 13.1 1.3 2.4 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein Lar_restr_allev PF14354.6 ORY11796.1 - 0.0017 18.7 10.3 0.016 15.6 1.2 2.8 2 1 1 3 3 3 2 Restriction alleviation protein Lar HypA PF01155.19 ORY11796.1 - 0.004 17.1 8.0 0.12 12.4 1.0 2.3 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 ORY11796.1 - 1.4 9.0 10.2 5.8 7.0 10.2 1.9 1 1 0 1 1 1 0 Double zinc ribbon Zn-ribbon_8 PF09723.10 ORY11796.1 - 2.6 8.2 9.7 9.7 6.4 0.4 3.3 2 1 1 3 3 3 0 Zinc ribbon domain TackOD1 PF18551.1 ORY11796.1 - 4.6 6.9 7.1 1.8 8.2 0.4 2.2 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 Glyco_transf_24 PF18404.1 ORY11797.1 - 2.5e-148 492.7 2.2 5e-148 491.7 2.2 1.6 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 ORY11797.1 - 7.6e-69 232.5 0.0 5.7e-68 229.6 0.0 2.5 3 0 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_15 PF18403.1 ORY11797.1 - 4e-56 190.3 0.4 5.7e-54 183.3 0.1 3.1 3 0 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_12 PF18400.1 ORY11797.1 - 4.5e-49 166.9 0.1 9.1e-49 165.9 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_13 PF18401.1 ORY11797.1 - 1.5e-45 154.4 0.2 4.6e-44 149.6 0.1 2.9 3 0 0 3 3 3 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 ORY11797.1 - 4.7e-42 142.5 0.0 1e-41 141.5 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.20 ORY11797.1 - 0.00019 21.1 0.3 0.00042 20.0 0.3 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 8 Cupin_1 PF00190.22 ORY11799.1 - 9.4e-14 51.3 0.2 1.7e-13 50.4 0.2 1.4 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.11 ORY11799.1 - 6.1e-05 22.7 0.0 0.0003 20.5 0.0 1.9 1 1 0 1 1 1 1 Cupin domain Coatomer_WDAD PF04053.14 ORY11801.1 - 1.8e-148 495.3 0.0 2.6e-148 494.8 0.0 1.3 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.11 ORY11801.1 - 1.9e-94 316.7 0.0 2.6e-94 316.3 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.32 ORY11801.1 - 1.7e-34 117.2 19.3 1.3e-07 32.1 0.3 7.6 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY11801.1 - 6.5e-07 29.6 0.8 0.081 13.2 0.0 5.6 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ORY11801.1 - 0.04 12.6 5.9 3.6 6.1 0.2 3.6 2 1 2 4 4 4 0 Nucleoporin Nup120/160 Clathrin PF00637.20 ORY11801.1 - 0.26 11.1 2.0 0.39 10.6 0.0 2.3 3 0 0 3 3 3 0 Region in Clathrin and VPS MFS_1 PF07690.16 ORY11802.1 - 6.5e-20 71.4 35.9 6.5e-20 71.4 35.9 3.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Wzz PF02706.15 ORY11802.1 - 0.2 12.0 3.7 1.6 9.1 0.4 3.1 2 0 0 2 2 2 0 Chain length determinant protein CH PF00307.31 ORY11803.1 - 0.041 14.1 0.0 0.081 13.1 0.0 1.4 1 0 0 1 1 1 0 Calponin homology (CH) domain Zn_clus PF00172.18 ORY11806.1 - 1.3e-08 34.8 14.0 2.7e-08 33.8 14.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.22 ORY11808.1 - 8.3e-44 150.1 0.0 1.6e-43 149.2 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 tRNA-synt_1b PF00579.25 ORY11809.1 - 5.6e-63 213.0 0.0 7.1e-63 212.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) ATP_bind_2 PF03668.15 ORY11810.1 - 0.12 11.7 0.2 0.21 10.9 0.0 1.4 2 0 0 2 2 2 0 P-loop ATPase protein family Indigoidine_A PF04227.12 ORY11811.1 - 4.8e-122 406.9 0.2 7.3e-122 406.3 0.2 1.3 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.24 ORY11811.1 - 2.1e-21 76.5 0.2 1.3e-10 41.1 0.1 3.1 2 1 0 2 2 2 2 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 ORY11811.1 - 0.0071 15.8 0.0 2.6 7.3 0.0 2.5 2 0 0 2 2 2 2 Phosphomethylpyrimidine kinase Ribophorin_I PF04597.14 ORY11812.1 - 4.1e-152 507.4 0.1 4.7e-152 507.2 0.1 1.0 1 0 0 1 1 1 1 Ribophorin I VTC PF09359.10 ORY11813.1 - 7.8e-99 330.5 1.7 1.7e-98 329.4 0.1 2.0 2 0 0 2 2 2 1 VTC domain SPX PF03105.19 ORY11813.1 - 3e-13 50.5 10.6 2.9e-05 24.2 0.6 3.4 1 1 2 3 3 3 3 SPX domain DUF202 PF02656.15 ORY11813.1 - 1.5e-11 44.6 5.8 2.9e-11 43.7 5.8 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF202) Pkinase PF00069.25 ORY11814.1 - 4.5e-31 108.2 0.0 7.2e-31 107.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY11814.1 - 1.1e-24 87.2 0.0 3.3e-24 85.6 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORY11814.1 - 0.0045 15.8 0.0 0.0071 15.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase YrbL-PhoP_reg PF10707.9 ORY11814.1 - 0.17 11.4 0.0 0.32 10.5 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL NifU_N PF01592.16 ORY11815.1 - 2.3e-53 179.7 0.0 2.9e-53 179.4 0.0 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain TSCPD PF12637.7 ORY11815.1 - 0.05 13.9 0.0 0.089 13.1 0.0 1.3 1 0 0 1 1 1 0 TSCPD domain UCH PF00443.29 ORY11816.1 - 1.4e-35 123.1 0.0 3.5e-35 121.8 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 ORY11816.1 - 1.5e-24 86.1 6.8 1.2e-19 70.4 0.8 3.2 2 0 0 2 2 2 2 Zn-finger in ubiquitin-hydrolases and other protein zf-UBP_var PF17807.1 ORY11816.1 - 1.5e-23 82.3 3.9 3.3e-22 78.0 0.5 2.6 2 0 0 2 2 2 2 Variant UBP zinc finger UBA PF00627.31 ORY11816.1 - 1.7e-21 75.8 0.0 2.4e-09 36.9 0.0 2.7 2 0 0 2 2 2 2 UBA/TS-N domain UCH_1 PF13423.6 ORY11816.1 - 2.7e-15 56.8 6.5 2.3e-14 53.7 0.0 3.7 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase UBA_4 PF14555.6 ORY11816.1 - 0.0063 16.3 0.0 0.013 15.3 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain MAM1 PF10434.9 ORY11816.1 - 0.054 13.1 0.4 2.5 7.7 0.0 2.3 2 0 0 2 2 2 0 Monopolin complex protein MAM1 DNA_pol_phi PF04931.13 ORY11817.1 - 1.1e-214 714.9 6.0 1.3e-214 714.6 6.0 1.1 1 0 0 1 1 1 1 DNA polymerase phi Nic96 PF04097.14 ORY11817.1 - 0.0054 15.3 0.2 0.01 14.3 0.2 1.4 1 0 0 1 1 1 1 Nup93/Nic96 BUD22 PF09073.10 ORY11817.1 - 0.83 8.9 20.9 1.6 8.0 20.9 1.3 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 ORY11817.1 - 3 7.2 23.8 5.6 6.3 23.8 1.3 1 0 0 1 1 1 0 SDA1 Rhodanese PF00581.20 ORY11818.1 - 2.5e-13 50.4 0.0 5.3e-13 49.4 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain SLD5_C PF16922.5 ORY11820.1 - 7.4e-18 64.5 0.3 1.5e-17 63.5 0.3 1.5 1 0 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus Sld5 PF05916.11 ORY11820.1 - 0.00043 20.7 0.1 0.0015 19.0 0.1 1.9 1 1 0 1 1 1 1 GINS complex protein CDH1_2_SANT_HL1 PF18375.1 ORY11820.1 - 0.12 13.1 0.0 0.29 11.8 0.0 1.7 1 0 0 1 1 1 0 CDH1/2 SANT-Helical linker 1 DLH PF01738.18 ORY11821.1 - 3e-17 62.9 0.0 1.1e-14 54.6 0.0 2.2 1 1 0 1 1 1 1 Dienelactone hydrolase family Rep_fac-A_C PF08646.10 ORY11822.1 - 1.6e-51 173.9 3.9 1e-49 168.0 1.4 2.7 3 0 0 3 3 3 2 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 ORY11822.1 - 4.2e-35 119.6 1.8 6.2e-35 119.0 1.1 1.7 2 0 0 2 2 2 1 Replication protein A OB domain Rep-A_N PF04057.12 ORY11822.1 - 1.4e-20 73.2 0.1 3.2e-20 72.0 0.1 1.6 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.25 ORY11822.1 - 9.4e-14 51.2 0.5 1.1e-08 34.9 0.0 3.9 4 0 0 4 4 4 2 OB-fold nucleic acid binding domain POT1 PF02765.17 ORY11822.1 - 0.00029 20.7 0.1 0.00088 19.1 0.0 1.9 2 0 0 2 2 2 1 Telomeric single stranded DNA binding POT1/CDC13 GTP_EFTU_D2 PF03144.25 ORY11822.1 - 0.017 15.5 0.6 0.087 13.2 0.1 2.2 2 0 0 2 2 2 0 Elongation factor Tu domain 2 CDC24_OB3 PF17244.2 ORY11822.1 - 0.028 14.1 0.2 1.1 8.9 0.1 2.8 2 1 0 2 2 2 0 Cell division control protein 24, OB domain 3 DUF4503 PF14951.6 ORY11822.1 - 0.084 11.3 1.6 0.083 11.3 0.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4503) ADH_zinc_N PF00107.26 ORY11824.1 - 2.2e-19 69.7 0.1 3.6e-19 69.0 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ORY11824.1 - 6.2e-19 69.4 0.0 9.5e-19 68.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ORY11824.1 - 1.7e-09 37.5 0.0 5.1e-08 32.8 0.0 2.3 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 ORY11824.1 - 0.0024 17.4 0.0 0.0035 16.9 0.0 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus Zn_clus PF00172.18 ORY11825.1 - 6.1e-06 26.3 14.7 6.1e-06 26.3 14.7 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 ORY11825.1 - 0.00056 18.8 2.8 0.00064 18.6 0.2 2.0 1 1 0 2 2 2 1 Fungal specific transcription factor domain Aldo_ket_red PF00248.21 ORY11826.1 - 1.3e-72 244.5 0.0 1.4e-72 244.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Abhydrolase_6 PF12697.7 ORY11827.1 - 3.5e-13 50.7 0.0 5e-13 50.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ORY11827.1 - 1e-08 35.2 0.1 2.4e-08 33.9 0.1 1.6 2 1 0 2 2 2 1 alpha/beta hydrolase fold Chlorophyllase PF07224.11 ORY11827.1 - 0.0062 15.6 0.0 0.0089 15.1 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase LIP PF03583.14 ORY11827.1 - 0.032 13.6 0.0 0.061 12.6 0.0 1.6 1 1 0 1 1 1 0 Secretory lipase Hydrolase_4 PF12146.8 ORY11827.1 - 0.037 13.3 0.0 0.11 11.7 0.0 1.7 2 0 0 2 2 2 0 Serine aminopeptidase, S33 DUF3089 PF11288.8 ORY11827.1 - 0.22 11.0 0.0 0.38 10.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Lip_prot_lig_C PF10437.9 ORY11828.1 - 0.031 14.3 1.5 26 4.9 0.0 3.6 2 1 1 3 3 3 0 Bacterial lipoate protein ligase C-terminus DUF370 PF04025.12 ORY11828.1 - 0.12 12.5 0.1 0.52 10.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF370) DUF4201 PF13870.6 ORY11828.1 - 0.43 10.3 52.8 0.44 10.3 20.1 3.9 2 2 2 4 4 4 0 Domain of unknown function (DUF4201) Filament PF00038.21 ORY11828.1 - 2.3 7.7 56.3 0.98 8.9 8.5 3.6 1 1 1 3 3 3 0 Intermediate filament protein AAA_13 PF13166.6 ORY11828.1 - 3.1 6.3 45.8 0.18 10.4 10.2 2.0 1 1 1 2 2 2 0 AAA domain TPR_MLP1_2 PF07926.12 ORY11828.1 - 6.8 6.8 65.0 0.072 13.2 22.9 4.4 2 2 0 3 3 3 0 TPR/MLP1/MLP2-like protein DUF812 PF05667.11 ORY11828.1 - 9.5 5.0 56.2 0.19 10.6 20.0 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF812) ubiquitin PF00240.23 ORY11829.1 - 1e-15 57.3 0.0 1.3e-09 37.7 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.8 ORY11829.1 - 1.1e-06 28.3 0.0 0.0013 18.5 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 ORY11829.1 - 2e-06 28.2 0.1 0.009 16.4 0.0 3.2 2 1 0 2 2 2 1 Ubiquitin-like domain UN_NPL4 PF11543.8 ORY11829.1 - 6.3e-05 23.4 0.0 0.00016 22.1 0.0 1.7 1 1 0 1 1 1 1 Nuclear pore localisation protein NPL4 Ubiquitin_4 PF18036.1 ORY11829.1 - 0.0001 22.3 0.4 0.26 11.4 0.1 3.4 2 2 0 2 2 2 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 ORY11829.1 - 0.00054 20.0 0.0 0.41 10.8 0.0 2.4 2 1 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 ORY11829.1 - 0.008 16.5 0.0 0.17 12.3 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin-like domain YukD PF08817.10 ORY11829.1 - 0.027 15.2 0.0 0.53 11.0 0.0 2.5 2 1 0 2 2 2 0 WXG100 protein secretion system (Wss), protein YukD DUF2407 PF10302.9 ORY11829.1 - 0.031 14.8 0.1 2.1 8.9 0.0 2.2 2 0 0 2 2 2 0 DUF2407 ubiquitin-like domain IBR PF01485.21 ORY11830.1 - 7.2e-14 51.8 43.9 1.2e-09 38.3 10.5 5.5 4 1 1 5 5 5 3 IBR domain, a half RING-finger domain FYVE PF01363.21 ORY11830.1 - 6 7.1 39.0 0.89 9.7 0.2 5.1 3 2 2 5 5 5 0 FYVE zinc finger AIRC PF00731.20 ORY11831.1 - 3.8e-58 195.3 0.0 7.8e-58 194.3 0.0 1.6 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.22 ORY11831.1 - 4e-53 179.5 0.0 6.4e-53 178.8 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain PurK_C PF17769.1 ORY11831.1 - 1.6e-17 62.9 0.0 4.9e-17 61.3 0.0 1.9 2 0 0 2 2 2 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain CPSase_L_D2 PF02786.17 ORY11831.1 - 2.3e-05 24.0 0.1 8.5e-05 22.1 0.1 2.0 1 1 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain AlaDh_PNT_C PF01262.21 ORY11831.1 - 0.00028 20.3 0.0 0.00046 19.5 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Dala_Dala_lig_C PF07478.13 ORY11831.1 - 0.00092 18.8 0.0 0.0051 16.4 0.0 2.0 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus Ribosomal_L18 PF17135.4 ORY11832.1 - 1.5e-89 298.4 1.7 1.7e-89 298.2 1.7 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 ORY11832.1 - 0.0034 18.1 2.3 0.0036 18.0 0.2 2.2 2 1 0 2 2 2 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Tra_M PF05261.11 ORY11832.1 - 0.16 12.0 0.0 0.2 11.6 0.0 1.2 1 0 0 1 1 1 0 TraM protein, DNA-binding Nudc_N PF14050.6 ORY11832.1 - 0.19 11.7 0.0 0.5 10.4 0.0 1.8 2 0 0 2 2 2 0 N-terminal conserved domain of Nudc. TPT PF03151.16 ORY11833.1 - 2.6e-26 92.6 20.2 3.4e-26 92.3 20.2 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 ORY11833.1 - 0.00033 20.0 22.6 0.00067 18.9 22.6 1.5 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 ORY11833.1 - 0.13 12.4 37.0 0.05 13.8 13.9 2.7 3 0 0 3 3 3 0 EamA-like transporter family NAD_binding_8 PF13450.6 ORY11834.1 - 9.6e-08 32.2 0.0 2e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 ORY11834.1 - 2.3e-05 23.9 0.0 0.00012 21.5 0.0 1.9 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 ORY11834.1 - 0.0012 18.1 0.1 0.025 13.8 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 ORY11834.1 - 0.0023 17.2 0.0 0.0048 16.2 0.0 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 ORY11834.1 - 0.0096 15.2 0.1 0.014 14.6 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 ORY11834.1 - 0.016 14.4 0.0 0.03 13.6 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 ORY11834.1 - 0.062 12.6 0.0 0.084 12.2 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase DAO PF01266.24 ORY11834.1 - 0.077 12.6 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase TrkA_N PF02254.18 ORY11834.1 - 0.091 13.0 0.0 0.28 11.5 0.0 1.8 2 0 0 2 2 1 0 TrkA-N domain Lycopene_cycl PF05834.12 ORY11834.1 - 0.11 11.5 0.1 0.2 10.7 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein HI0933_like PF03486.14 ORY11834.1 - 0.12 11.1 0.1 0.22 10.2 0.0 1.4 2 0 0 2 2 2 0 HI0933-like protein Aldedh PF00171.22 ORY11835.1 - 2.9e-13 49.2 4.1 6.2e-06 25.0 2.6 2.6 2 1 0 2 2 2 2 Aldehyde dehydrogenase family DUF1542 PF07564.11 ORY11835.1 - 1.8 8.8 4.2 2.2 8.4 2.2 2.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1542) Glyco_hydro_16 PF00722.21 ORY11836.1 - 3.7e-44 150.3 2.7 5.9e-44 149.6 2.7 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Glyco_hydro_20 PF00728.22 ORY11837.1 - 2.5e-91 306.7 0.7 3.2e-91 306.3 0.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 ORY11837.1 - 1.1e-26 94.1 0.0 4e-26 92.3 0.0 1.9 2 0 0 2 2 2 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 ORY11837.1 - 9.6e-08 32.9 0.0 6.4e-07 30.2 0.0 2.3 3 0 0 3 3 3 1 Glycosyl hydrolase family 20, domain 2 HpaB_N PF11794.8 ORY11837.1 - 0.18 11.5 0.0 0.29 10.7 0.0 1.2 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal PHY PF00360.20 ORY11837.1 - 0.19 11.0 0.9 0.88 8.8 0.1 2.2 2 0 0 2 2 2 0 Phytochrome region p450 PF00067.22 ORY11838.1 - 5.4e-63 213.3 0.0 7.2e-63 212.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_2 PF00891.18 ORY11840.1 - 1.5e-21 76.6 0.0 2.2e-21 76.1 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation PF08100.11 ORY11840.1 - 4.5e-06 26.6 0.1 0.0035 17.3 0.6 2.7 1 1 1 2 2 2 2 Dimerisation domain Dimerisation2 PF16864.5 ORY11840.1 - 0.0054 16.7 0.0 0.0091 16.0 0.0 1.4 1 0 0 1 1 1 1 Dimerisation domain Plasmodium_Vir PF05795.11 ORY11842.1 - 0.039 13.4 0.5 0.045 13.2 0.5 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein TPT PF03151.16 ORY11843.1 - 5.8e-20 71.8 8.9 9.4e-20 71.1 8.9 1.3 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 ORY11843.1 - 1.2e-05 25.5 27.9 0.008 16.3 5.8 2.6 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 ORY11843.1 - 0.028 13.6 18.9 0.083 12.1 14.6 2.2 2 0 0 2 2 2 0 UAA transporter family CDC45 PF02724.14 ORY11843.1 - 0.03 12.6 4.2 0.051 11.9 4.2 1.3 1 0 0 1 1 1 0 CDC45-like protein GRIM-19 PF06212.12 ORY11843.1 - 0.048 13.6 0.0 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 GRIM-19 protein PUNUT PF16913.5 ORY11843.1 - 0.3 10.3 12.4 0.063 12.5 8.1 1.9 2 0 0 2 2 2 0 Purine nucleobase transmembrane transport CrgA PF06781.12 ORY11843.1 - 0.94 9.6 2.6 41 4.3 0.1 3.0 2 0 0 2 2 2 0 Cell division protein CrgA Cwf_Cwc_15 PF04889.12 ORY11843.1 - 5.4 6.7 15.7 0.16 11.7 9.6 1.4 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Mo25 PF08569.11 ORY11844.1 - 4e-113 378.1 0.1 1.1e-111 373.3 0.1 2.0 1 1 0 1 1 1 1 Mo25-like Pkinase PF00069.25 ORY11844.1 - 1.7e-31 109.6 0.0 3.9e-31 108.4 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY11844.1 - 6.6e-12 45.3 0.0 1.7e-11 43.9 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 ORY11844.1 - 6.8e-06 26.2 0.0 0.045 13.7 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family muHD PF10291.9 ORY11846.1 - 4.6e-73 245.9 0.0 6.6e-73 245.4 0.0 1.2 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.23 ORY11846.1 - 0.00069 19.8 0.3 0.0019 18.4 0.0 1.9 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain HATPase_c PF02518.26 ORY11847.1 - 1.1e-25 90.3 0.0 2.2e-25 89.3 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 ORY11847.1 - 4e-19 68.4 0.1 8.3e-19 67.4 0.1 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.12 ORY11847.1 - 4.2e-18 65.4 4.0 1.7e-11 44.2 0.7 3.6 3 0 0 3 3 3 3 PAS fold Response_reg PF00072.24 ORY11847.1 - 6.9e-16 58.4 0.0 1.7e-15 57.2 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain PAS PF00989.25 ORY11847.1 - 5e-08 32.9 0.0 0.00032 20.7 0.0 2.6 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.10 ORY11847.1 - 4.8e-07 30.0 0.3 4.9e-06 26.7 0.1 2.8 3 0 0 3 3 3 1 PAS fold PAS_9 PF13426.7 ORY11847.1 - 1.3e-06 28.6 0.0 0.00074 19.7 0.0 3.3 3 0 0 3 3 3 1 PAS domain PAS_8 PF13188.7 ORY11847.1 - 3.5e-05 23.7 0.0 0.037 14.1 0.0 2.6 2 0 0 2 2 2 2 PAS domain STIMATE PF12400.8 ORY11848.1 - 8.4e-42 142.7 3.2 8.4e-42 142.7 3.2 1.5 2 0 0 2 2 2 1 STIMATE family FKBP_C PF00254.28 ORY11848.1 - 1.4e-31 108.6 0.0 2.3e-31 107.9 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase CD52 PF15116.6 ORY11848.1 - 0.46 10.6 2.0 3.8 7.6 0.3 2.9 2 0 0 2 2 2 0 CAMPATH-1 antigen Prenyltrans PF00432.21 ORY11849.1 - 0.1 12.4 0.0 0.1 12.4 0.0 2.4 3 0 0 3 3 3 0 Prenyltransferase and squalene oxidase repeat MFS_1 PF07690.16 ORY11850.1 - 1.2e-36 126.4 51.4 1.1e-35 123.2 49.9 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 ORY11850.1 - 1.5e-11 43.5 8.8 2.2e-11 42.9 8.8 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) PHO4 PF01384.20 ORY11851.1 - 0.4 9.7 6.5 0.91 8.5 6.6 1.4 1 1 0 1 1 1 0 Phosphate transporter family Methyltransf_23 PF13489.6 ORY11852.1 - 4.7e-07 29.8 0.0 6.5e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY11852.1 - 1.6e-05 25.5 0.0 3e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY11852.1 - 0.001 19.7 0.0 0.0017 19.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY11852.1 - 0.0028 18.4 0.0 0.0055 17.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY11852.1 - 0.02 14.7 0.0 0.029 14.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain CtsR_C PF17727.1 ORY11852.1 - 0.15 12.2 0.1 0.28 11.3 0.1 1.4 1 0 0 1 1 1 0 CtsR C-terminal dimerization domain p450 PF00067.22 ORY11853.1 - 6.3e-27 94.4 0.0 9.1e-27 93.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 ORY11854.1 - 8.9e-36 123.6 0.0 1.1e-35 123.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 GST_N PF02798.20 ORY11855.1 - 1e-15 57.8 0.2 3.2e-15 56.2 0.0 1.9 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 ORY11855.1 - 4.1e-15 55.8 0.0 2e-14 53.6 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 ORY11855.1 - 3.3e-14 53.0 0.0 5.8e-14 52.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 ORY11855.1 - 6.9e-14 51.8 0.0 5.4e-12 45.8 0.0 2.4 1 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 ORY11855.1 - 1.1e-10 41.7 0.0 2.4e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 ORY11855.1 - 8.5e-08 32.1 0.0 1.8e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Ist1 PF03398.14 ORY11856.1 - 1.4e-56 190.9 0.4 1.9e-56 190.5 0.4 1.2 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Aspzincin_M35 PF14521.6 ORY11866.1 - 0.0027 18.3 0.3 0.079 13.5 0.2 2.8 3 0 0 3 3 3 1 Lysine-specific metallo-endopeptidase RIIa PF02197.17 ORY11866.1 - 0.1 12.3 0.1 0.22 11.2 0.1 1.6 1 0 0 1 1 1 0 Regulatory subunit of type II PKA R-subunit TCP PF03634.13 ORY11867.1 - 0.18 12.4 4.3 0.31 11.6 4.3 1.4 1 0 0 1 1 1 0 TCP family transcription factor Dapper PF15268.6 ORY11867.1 - 0.21 10.4 7.3 0.3 9.9 7.3 1.2 1 0 0 1 1 1 0 Dapper Macoilin PF09726.9 ORY11867.1 - 1.7 7.1 9.9 2.3 6.7 9.9 1.1 1 0 0 1 1 1 0 Macoilin family Nop14 PF04147.12 ORY11867.1 - 1.8 6.7 10.5 2.5 6.2 10.5 1.1 1 0 0 1 1 1 0 Nop14-like family Zip PF02535.22 ORY11867.1 - 2.9 7.0 8.1 4 6.6 8.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter NPR3 PF03666.13 ORY11867.1 - 4.8 5.9 17.7 7 5.3 17.7 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Otopetrin PF03189.13 ORY11867.1 - 5.1 5.8 4.9 7.3 5.3 4.9 1.1 1 0 0 1 1 1 0 Otopetrin CDC45 PF02724.14 ORY11867.1 - 7.3 4.7 10.8 9.7 4.3 10.8 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF3328 PF11807.8 ORY11868.1 - 2.7e-17 63.3 0.4 2.8e-17 63.2 0.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Pectate_lyase PF03211.13 ORY11869.1 - 9.5e-86 286.5 7.3 1.2e-85 286.2 7.3 1.0 1 0 0 1 1 1 1 Pectate lyase GDPD PF03009.17 ORY11870.1 - 2.1e-70 237.4 0.0 3.7e-70 236.6 0.0 1.4 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.7 ORY11870.1 - 9.1e-25 87.1 0.0 1.4e-08 35.2 0.0 3.9 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY11870.1 - 5.6e-24 84.2 0.8 2.8e-10 40.5 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeats (many copies) SPX PF03105.19 ORY11870.1 - 3e-20 73.5 17.0 9.9e-13 48.7 0.0 4.3 3 1 2 5 5 5 3 SPX domain Ank_5 PF13857.6 ORY11870.1 - 2.5e-16 59.5 0.1 4.3e-06 26.9 0.0 4.6 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY11870.1 - 5.6e-16 57.0 0.3 0.014 15.9 0.0 7.2 7 0 0 7 7 7 3 Ankyrin repeat Ank PF00023.30 ORY11870.1 - 8.9e-16 57.6 1.9 0.00023 21.5 0.0 6.0 5 0 0 5 5 5 3 Ankyrin repeat XAP5 PF04921.14 ORY11871.1 - 2.1e-88 296.4 0.1 3.1e-88 295.8 0.1 1.2 1 0 0 1 1 1 1 XAP5, circadian clock regulator DUF4604 PF15377.6 ORY11871.1 - 0.00042 20.8 1.9 0.00042 20.8 1.9 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF4604) GAGA_bind PF06217.12 ORY11871.1 - 0.0046 17.3 0.5 0.0093 16.3 0.5 1.5 1 1 0 1 1 1 1 GAGA binding protein-like family UBA PF00627.31 ORY11872.1 - 8.5e-08 32.0 0.0 1.5e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 UBA/TS-N domain AT_hook PF02178.19 ORY11872.1 - 0.037 13.9 4.5 0.19 11.7 4.5 2.3 1 0 0 1 1 1 0 AT hook motif KOG2701 PF09762.9 ORY11872.1 - 0.21 11.8 0.4 0.49 10.6 0.4 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein (DUF2037) Polysacc_deac_1 PF01522.21 ORY11873.1 - 1.1e-27 96.3 0.0 1.9e-27 95.6 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.19 ORY11873.1 - 1.4e-15 57.4 101.9 1.5e-07 31.7 16.8 5.8 5 2 2 7 7 7 3 Chitin recognition protein Nefa_Nip30_N PF10187.9 ORY11874.1 - 1.8e-31 108.6 14.7 1.8e-31 108.6 14.7 1.8 2 0 0 2 2 2 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 UVR PF02151.19 ORY11874.1 - 0.0016 18.1 2.0 0.0056 16.4 2.0 1.9 1 0 0 1 1 1 1 UvrB/uvrC motif DUF572 PF04502.13 ORY11874.1 - 0.094 12.3 16.2 0.13 11.8 16.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) SAPS PF04499.15 ORY11874.1 - 6.8 5.4 8.6 10 4.7 8.6 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Aldo_ket_red PF00248.21 ORY11875.1 - 3e-50 171.1 0.0 1.2e-48 165.8 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family JAB PF01398.21 ORY11877.1 - 1.9e-08 34.3 0.1 2.4e-07 30.7 0.1 2.3 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease GST_N_3 PF13417.6 ORY11878.1 - 4.7e-20 71.8 0.0 1.1e-19 70.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 ORY11878.1 - 4.3e-17 62.2 0.1 1.5e-16 60.4 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 ORY11878.1 - 3.5e-08 33.7 0.0 8e-08 32.5 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 ORY11878.1 - 4.1e-05 23.5 0.2 9.4e-05 22.4 0.2 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 ORY11878.1 - 0.0072 16.9 0.0 0.013 16.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 ORY11878.1 - 0.019 15.7 0.0 0.048 14.4 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain GST_C PF00043.25 ORY11878.1 - 0.036 14.3 0.0 0.12 12.6 0.0 1.9 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 ORY11878.1 - 0.054 13.7 0.0 0.17 12.1 0.0 1.9 1 0 0 1 1 1 0 Glutaredoxin Big_4 PF07532.11 ORY11879.1 - 0.016 15.0 0.8 9.1 6.1 0.6 3.7 1 1 0 1 1 1 0 Bacterial Ig-like domain (group 4) Herpes_TK_C PF08465.10 ORY11879.1 - 0.038 13.7 0.3 37 4.1 0.0 3.7 4 0 0 4 4 4 0 Thymidine kinase from Herpesvirus C-terminal ETC_C1_NDUFA5 PF04716.14 ORY11879.1 - 0.09 12.6 1.6 59 3.6 0.0 3.0 1 1 2 3 3 3 0 ETC complex I subunit conserved region Sde2_N_Ubi PF13019.6 ORY11879.1 - 0.11 12.3 0.4 3.2 7.6 0.2 2.2 1 1 1 2 2 2 0 Silencing defective 2 N-terminal ubiquitin domain Esterase PF00756.20 ORY11880.1 - 0.015 14.9 0.1 0.056 13.1 0.1 1.8 1 1 0 1 1 1 0 Putative esterase Esterase_phd PF10503.9 ORY11880.1 - 0.032 13.7 0.3 0.06 12.8 0.2 1.4 1 1 0 1 1 1 0 Esterase PHB depolymerase Inhibitor_I78 PF11720.8 ORY11881.1 - 2.3e-08 34.0 0.0 2.8e-08 33.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase inhibitor I78 family potato_inhibit PF00280.18 ORY11881.1 - 0.0004 21.0 0.0 0.00052 20.6 0.0 1.1 1 0 0 1 1 1 1 Potato inhibitor I family RIC1 PF07064.13 ORY11884.1 - 5e-96 321.0 0.0 6.7e-96 320.5 0.0 1.2 1 0 0 1 1 1 1 RIC1 Hira PF07569.11 ORY11885.1 - 1e-84 283.7 0.0 4.6e-84 281.6 0.0 2.0 2 0 0 2 2 2 1 TUP1-like enhancer of split WD40 PF00400.32 ORY11885.1 - 7.7e-28 96.2 25.6 1.6e-05 25.6 0.0 9.1 7 1 1 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY11885.1 - 3.6e-13 49.6 0.0 0.13 12.5 0.0 6.4 4 1 3 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain HIRA_B PF09453.10 ORY11885.1 - 1.1e-12 47.5 0.8 2.3e-12 46.4 0.8 1.6 1 0 0 1 1 1 1 HIRA B motif PD40 PF07676.12 ORY11885.1 - 0.00077 19.3 0.5 11 6.0 0.0 5.3 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 ORY11885.1 - 0.0013 17.7 1.2 0.11 11.4 0.1 4.1 3 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein IKI3 PF04762.12 ORY11885.1 - 0.0073 14.4 0.0 0.036 12.1 0.0 2.0 2 0 0 2 2 2 1 IKI3 family Fungal_trans PF04082.18 ORY11886.1 - 2.9e-10 39.6 0.0 4.4e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 ORY11887.1 - 4.6e-36 124.5 33.7 4.6e-36 124.5 33.7 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY11887.1 - 1.1e-09 37.7 8.7 1.1e-09 37.7 8.7 2.0 2 0 0 2 2 2 1 Sugar (and other) transporter TMEM237 PF15383.6 ORY11887.1 - 0.32 10.1 1.2 15 4.5 0.0 2.6 2 0 0 2 2 2 0 Transmembrane protein 237 adh_short PF00106.25 ORY11888.1 - 9.1e-23 80.7 0.1 8.5e-13 48.2 0.0 2.1 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 ORY11888.1 - 6.4e-12 45.5 0.1 6.4e-09 35.7 0.1 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY11888.1 - 1.9e-07 31.2 0.4 3.7e-05 23.7 0.5 2.1 1 1 1 2 2 2 2 KR domain Polysacc_synt_2 PF02719.15 ORY11888.1 - 0.00032 19.9 0.1 0.00051 19.3 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.20 ORY11888.1 - 0.00042 20.4 0.0 0.0006 19.9 0.0 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Eno-Rase_NADH_b PF12242.8 ORY11888.1 - 0.05 13.4 0.0 0.25 11.1 0.0 1.9 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ThiF PF00899.21 ORY11888.1 - 0.097 12.0 0.1 0.21 10.9 0.0 1.5 2 0 0 2 2 2 0 ThiF family PcrB PF01884.17 ORY11888.1 - 0.1 12.1 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 PcrB family 2-Hacid_dh_C PF02826.19 ORY11888.1 - 0.14 11.5 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain EF-hand_1 PF00036.32 ORY11891.1 - 1.1e-41 137.3 12.9 7.8e-10 37.6 0.9 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 ORY11891.1 - 3.5e-36 123.5 5.8 3.9e-19 68.9 2.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 ORY11891.1 - 6.8e-35 118.7 11.4 2.3e-15 56.1 0.6 4.0 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 ORY11891.1 - 2.1e-30 102.0 9.5 1.9e-09 36.7 0.2 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 ORY11891.1 - 6.5e-26 88.6 10.6 2.6e-06 26.7 0.3 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 ORY11891.1 - 1.5e-16 60.5 0.4 2.3e-09 37.4 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 ORY11891.1 - 3.4e-09 36.6 1.9 0.00075 19.4 0.2 2.3 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 ORY11891.1 - 5.6e-09 36.3 0.2 0.0016 18.7 0.1 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.13 ORY11891.1 - 9.9e-07 28.7 0.0 0.0077 16.2 0.0 3.0 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.10 ORY11891.1 - 5.8e-06 26.3 1.6 2.3e-05 24.4 0.2 2.3 2 1 0 2 2 2 1 Ca2+ insensitive EF hand EF-hand_11 PF08976.11 ORY11891.1 - 9.1e-05 23.3 0.2 0.0022 18.8 0.1 2.0 1 1 1 2 2 2 1 EF-hand domain TerB PF05099.13 ORY11891.1 - 0.00012 22.0 0.3 0.35 10.8 0.0 2.2 1 1 1 2 2 2 2 Tellurite resistance protein TerB Caleosin PF05042.13 ORY11891.1 - 0.00045 20.2 1.8 0.44 10.5 0.0 3.5 1 1 3 4 4 4 1 Caleosin related protein RNA_pol_Rpb4 PF03874.16 ORY11891.1 - 0.00062 20.1 0.8 0.66 10.3 0.1 2.7 2 1 1 3 3 3 2 RNA polymerase Rpb4 DUF3349 PF11829.8 ORY11891.1 - 0.0014 19.3 0.4 3.7 8.4 0.0 2.9 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) Dockerin_1 PF00404.18 ORY11891.1 - 0.0053 16.9 7.0 0.38 11.0 0.8 2.9 1 1 2 3 3 3 2 Dockerin type I domain DUF5580 PF17743.1 ORY11891.1 - 0.006 15.2 0.0 0.0062 15.1 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5580) SurA_N_2 PF13623.6 ORY11891.1 - 0.0091 15.9 0.9 0.32 10.9 0.1 2.2 1 1 1 2 2 2 1 SurA N-terminal domain EF-hand_14 PF17959.1 ORY11891.1 - 0.012 16.0 0.5 6.2 7.2 0.1 2.4 1 1 1 2 2 2 0 EF-hand domain Poly_export PF02563.16 ORY11891.1 - 0.023 14.9 0.0 0.18 12.1 0.0 2.5 2 1 0 2 2 2 0 Polysaccharide biosynthesis/export protein DUF4497 PF14924.6 ORY11891.1 - 0.036 14.5 0.0 8.7 6.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4497) RuvA_C PF07499.13 ORY11891.1 - 0.058 13.9 0.1 8.5 6.9 0.0 3.0 3 0 0 3 3 3 0 RuvA, C-terminal domain MotA_activ PF09114.10 ORY11891.1 - 0.061 13.4 0.3 1.2 9.3 0.0 2.3 1 1 0 2 2 2 0 Transcription factor MotA, activation domain dCache_2 PF08269.11 ORY11891.1 - 0.066 12.4 0.1 1.1 8.4 0.1 2.1 1 1 1 2 2 2 0 Cache domain DUF5132 PF17195.4 ORY11891.1 - 0.15 12.2 0.5 21 5.3 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF5132) RloB PF13707.6 ORY11891.1 - 0.16 12.2 1.1 0.76 9.9 0.2 2.0 1 1 1 2 2 2 0 RloB-like protein SNARE PF05739.19 ORY11893.1 - 1.1e-12 47.7 0.5 2.4e-12 46.6 0.5 1.6 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 ORY11893.1 - 0.0002 21.1 10.8 0.051 13.2 0.8 2.2 2 0 0 2 2 2 2 Syntaxin Syntaxin_2 PF14523.6 ORY11893.1 - 0.0025 18.1 8.1 0.017 15.4 3.0 2.5 2 1 0 2 2 2 1 Syntaxin-like protein DNA_repr_REX1B PF14966.6 ORY11893.1 - 0.0069 17.0 2.8 0.012 16.2 0.2 2.5 2 1 1 3 3 3 1 DNA repair REX1-B MCPsignal PF00015.21 ORY11893.1 - 0.027 14.3 5.9 0.08 12.7 0.3 2.6 3 0 0 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain EBV-NA3 PF05009.12 ORY11893.1 - 0.073 12.6 0.1 0.11 12.0 0.1 1.2 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) DASH_Dad4 PF08650.10 ORY11893.1 - 0.14 12.1 0.5 3.8 7.5 0.0 2.8 2 0 0 2 2 2 0 DASH complex subunit Dad4 DUF812 PF05667.11 ORY11893.1 - 0.63 8.9 10.3 5.9 5.6 8.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF812) TMPIT PF07851.13 ORY11893.1 - 0.65 9.2 7.3 0.79 8.9 2.3 2.2 2 0 0 2 2 2 0 TMPIT-like protein SlyX PF04102.12 ORY11893.1 - 8.3 7.1 17.2 2.7 8.7 0.6 4.0 3 2 1 4 4 4 0 SlyX HET PF06985.11 ORY11896.1 - 3.6e-24 85.8 0.1 4.4e-24 85.5 0.1 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) UPF0113 PF03657.13 ORY11897.1 - 6.2e-26 90.5 0.0 1.2e-25 89.5 0.0 1.5 2 0 0 2 2 2 1 UPF0113 PUA domain UPF0113_N PF17833.1 ORY11897.1 - 1.4e-25 89.6 0.0 1.9e-25 89.2 0.0 1.2 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain PUA PF01472.20 ORY11897.1 - 0.021 14.8 0.0 0.031 14.2 0.0 1.3 1 0 0 1 1 1 0 PUA domain NOC3p PF07540.11 ORY11898.1 - 5.8e-32 110.0 0.1 5.8e-32 110.0 0.1 2.5 2 1 0 2 2 2 1 Nucleolar complex-associated protein CBF PF03914.17 ORY11898.1 - 1.6e-26 93.4 0.0 1.6e-26 93.4 0.0 2.2 2 1 0 2 2 2 1 CBF/Mak21 family DUF4611 PF15387.6 ORY11898.1 - 0.17 12.1 10.5 0.39 11.0 0.6 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) SKG6 PF08693.10 ORY11899.1 - 5.6e-06 25.7 2.3 8.8e-06 25.0 2.3 1.3 1 0 0 1 1 1 1 Transmembrane alpha-helix domain RicinB_lectin_2 PF14200.6 ORY11899.1 - 0.039 14.7 3.3 0.084 13.6 1.3 2.3 1 1 1 2 2 2 0 Ricin-type beta-trefoil lectin domain-like EphA2_TM PF14575.6 ORY11899.1 - 0.11 13.4 0.0 0.22 12.4 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF1849 PF08904.11 ORY11899.1 - 0.11 12.0 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1849) DUF4381 PF14316.6 ORY11899.1 - 0.15 12.3 0.0 0.26 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Herpes_gE PF02480.16 ORY11899.1 - 0.19 10.4 0.0 0.26 10.0 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E MSA-2c PF12238.8 ORY11899.1 - 5.5 6.9 9.2 11 6.0 9.2 1.4 1 0 0 1 1 1 0 Merozoite surface antigen 2c Tyrosinase PF00264.20 ORY11900.1 - 8.1e-51 173.4 0.2 1e-50 173.1 0.2 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase zf-Tim10_DDP PF02953.15 ORY11901.1 - 1.3e-24 85.6 2.1 1.9e-24 85.1 2.1 1.3 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Nup160 PF11715.8 ORY11901.1 - 0.04 12.6 0.0 0.04 12.6 0.0 1.1 1 0 0 1 1 1 0 Nucleoporin Nup120/160 TerB_C PF15615.6 ORY11901.1 - 0.058 13.7 0.3 0.09 13.1 0.0 1.4 2 0 0 2 2 2 0 TerB-C domain DUF3361 PF11841.8 ORY11901.1 - 0.075 13.0 0.1 0.23 11.4 0.0 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF3361) Lectin_leg-like PF03388.13 ORY11902.1 - 4e-62 209.6 0.0 4.8e-62 209.3 0.0 1.0 1 0 0 1 1 1 1 Legume-like lectin family Lectin_legB PF00139.19 ORY11902.1 - 0.0083 15.7 0.0 0.66 9.5 0.0 2.2 1 1 0 1 1 1 1 Legume lectin domain ATG27 PF09451.10 ORY11902.1 - 0.064 13.1 0.1 0.094 12.6 0.1 1.2 1 0 0 1 1 1 0 Autophagy-related protein 27 ThiF PF00899.21 ORY11903.1 - 7.7e-39 133.5 0.0 1.3e-38 132.8 0.0 1.2 1 0 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 ORY11903.1 - 0.0029 17.9 1.1 0.036 14.3 1.1 2.3 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 ORY11903.1 - 0.0047 17.2 0.5 0.014 15.6 0.0 2.0 2 0 0 2 2 2 1 TrkA-N domain AlaDh_PNT_C PF01262.21 ORY11903.1 - 0.0089 15.3 0.1 0.019 14.3 0.1 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 ORY11903.1 - 0.018 14.6 0.1 0.036 13.6 0.1 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain GIDA PF01134.22 ORY11903.1 - 0.023 13.8 0.5 0.036 13.1 0.5 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A ApbA PF02558.16 ORY11903.1 - 0.061 13.0 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 ORY11903.1 - 0.065 13.1 0.0 0.17 11.7 0.0 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 ORY11903.1 - 0.1 11.8 0.4 0.16 11.2 0.4 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 ORY11903.1 - 0.14 12.7 0.5 1.5 9.5 0.2 2.6 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Melibiase_2 PF16499.5 ORY11903.1 - 0.16 11.1 0.0 0.26 10.4 0.0 1.2 1 0 0 1 1 1 0 Alpha galactosidase A Coatomer_E PF04733.14 ORY11903.1 - 0.17 11.3 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 Coatomer epsilon subunit Endonuclease_NS PF01223.23 ORY11904.1 - 5.1e-66 222.7 0.0 6.1e-66 222.5 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease FAP PF07174.11 ORY11904.1 - 0.28 10.6 15.8 0.39 10.1 15.8 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Tir_receptor_C PF07489.11 ORY11904.1 - 0.47 10.4 2.3 0.73 9.8 2.3 1.2 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus PRiA4_ORF3 PF07929.11 ORY11905.1 - 1.2e-24 86.9 0.0 3e-24 85.7 0.0 1.5 1 1 0 1 1 1 1 Plasmid pRiA4b ORF-3-like protein zf-MYND PF01753.18 ORY11905.1 - 3.2e-11 43.1 11.9 5.2e-11 42.4 11.9 1.4 1 0 0 1 1 1 1 MYND finger Astacin PF01400.24 ORY11906.1 - 1.5e-07 31.2 1.5 1.1e-05 25.2 0.2 2.6 2 1 0 2 2 2 2 Astacin (Peptidase family M12A) zf-C2H2 PF00096.26 ORY11907.1 - 9.2e-10 38.4 8.2 0.0035 17.7 0.8 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY11907.1 - 7.5e-05 23.3 9.3 0.18 12.7 0.5 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger VSP PF03302.13 ORY11907.1 - 0.00028 19.9 1.3 0.00055 18.9 1.3 1.4 1 0 0 1 1 1 1 Giardia variant-specific surface protein C1_4 PF07975.12 ORY11907.1 - 0.094 13.0 1.2 0.77 10.0 0.9 2.3 1 1 1 2 2 2 0 TFIIH C1-like domain zf-C2H2_aberr PF17017.5 ORY11907.1 - 0.12 12.5 0.5 0.23 11.6 0.5 1.4 1 0 0 1 1 1 0 Aberrant zinc-finger zf-H2C2_2 PF13465.6 ORY11907.1 - 0.22 12.0 15.0 1.5 9.4 1.7 4.3 4 0 0 4 4 4 0 Zinc-finger double domain zf-DNA_Pol PF08996.10 ORY11907.1 - 0.63 9.8 3.0 3 7.5 3.0 1.9 1 1 0 1 1 1 0 DNA Polymerase alpha zinc finger MraY_sig1 PF10555.9 ORY11907.1 - 1.3 8.7 2.9 3.1 7.5 2.9 1.6 1 0 0 1 1 1 0 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 AJAP1_PANP_C PF15298.6 ORY11907.1 - 1.5 9.0 3.7 0.58 10.3 0.7 1.8 2 0 0 2 2 2 0 AJAP1/PANP C-terminus Adeno_E3_CR2 PF02439.15 ORY11907.1 - 2.1 8.1 5.4 3.9 7.3 5.4 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Pheromone PF08015.11 ORY11907.1 - 7.4 7.7 15.7 4 8.5 5.2 4.3 3 1 0 3 3 3 0 Fungal mating-type pheromone SRTM1 PF15872.5 ORY11908.1 - 0.023 14.8 0.0 0.041 14.0 0.0 1.4 1 0 0 1 1 1 0 Serine-rich and transmembrane domain-containing protein 1 Herpes_gE PF02480.16 ORY11908.1 - 0.024 13.4 0.0 0.031 13.0 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E GPI-anchored PF10342.9 ORY11908.1 - 0.026 15.3 0.1 0.026 15.3 0.1 2.0 1 1 1 2 2 2 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Amnionless PF14828.6 ORY11908.1 - 0.072 11.9 0.1 0.1 11.4 0.1 1.1 1 0 0 1 1 1 0 Amnionless MGC-24 PF05283.11 ORY11908.1 - 0.075 13.5 0.1 0.12 12.9 0.1 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin TMEM51 PF15345.6 ORY11908.1 - 0.08 12.8 0.1 0.11 12.3 0.1 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 SR-25 PF10500.9 ORY11908.1 - 6.6 6.3 6.3 10 5.6 6.3 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein TMEM154 PF15102.6 ORY11908.1 - 7 6.6 5.1 25 4.8 5.1 1.7 1 1 0 1 1 1 0 TMEM154 protein family Bac_rhamnosid PF05592.11 ORY11913.1 - 0.14 12.1 0.1 0.32 11.0 0.1 1.6 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase concanavalin-like domain Lipase_3 PF01764.25 ORY11914.1 - 2.2e-24 85.9 0.0 3.2e-23 82.2 0.0 2.2 2 0 0 2 2 2 1 Lipase (class 3) ICAP-1_inte_bdg PF10480.9 ORY11914.1 - 0.0032 17.5 0.3 0.0032 17.5 0.3 2.3 2 0 0 2 2 2 1 Beta-1 integrin binding protein Abhydrolase_6 PF12697.7 ORY11914.1 - 0.031 14.9 0.5 0.052 14.1 0.0 1.9 2 1 0 2 2 2 0 Alpha/beta hydrolase family PGAP1 PF07819.13 ORY11914.1 - 0.037 13.8 0.0 0.08 12.6 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein Chlorophyllase2 PF12740.7 ORY11914.1 - 0.046 12.6 0.0 0.079 11.9 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme 1-cysPrx_C PF10417.9 ORY11914.1 - 0.074 12.9 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 C-terminal domain of 1-Cys peroxiredoxin TGBp3 PF02495.17 ORY11914.1 - 0.19 11.4 0.0 0.58 9.9 0.0 1.8 2 0 0 2 2 2 0 Triple gene block 3 PRP38 PF03371.15 ORY11915.1 - 1.4e-58 197.6 0.0 1.7e-58 197.4 0.0 1.1 1 0 0 1 1 1 1 PRP38 family PRP38_assoc PF12871.7 ORY11915.1 - 0.001 19.7 30.2 0.001 19.7 30.2 2.2 2 0 0 2 2 2 1 Pre-mRNA-splicing factor 38-associated hydrophilic C-term RSRP PF17069.5 ORY11915.1 - 4.2 6.8 31.5 5.7 6.4 31.5 1.1 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 TRH PF05438.12 ORY11916.1 - 0.055 13.2 0.1 0.083 12.6 0.1 1.2 1 0 0 1 1 1 0 Thyrotropin-releasing hormone (TRH) DUF3693 PF12472.8 ORY11916.1 - 0.21 11.3 0.3 0.62 9.8 0.3 1.7 1 0 0 1 1 1 0 Phage related protein Pkinase PF00069.25 ORY11917.1 - 1.7e-73 247.3 0.0 2.2e-73 246.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY11917.1 - 5.4e-38 130.8 0.0 8.2e-38 130.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY11917.1 - 4e-06 26.4 0.0 6.7e-06 25.6 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Med13_C PF06333.12 ORY11917.1 - 0.11 11.8 12.6 0.14 11.4 12.6 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain Rad21_Rec8 PF04824.16 ORY11917.1 - 0.13 11.6 0.3 0.31 10.3 0.3 1.6 1 0 0 1 1 1 0 Conserved region of Rad21 / Rec8 like protein Mucin PF01456.17 ORY11917.1 - 5 7.1 15.2 8.4 6.4 15.2 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Voltage_CLC PF00654.20 ORY11918.1 - 2.6e-89 300.0 29.6 4e-89 299.3 29.6 1.3 1 0 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.28 ORY11918.1 - 3.1e-05 24.3 0.0 0.0098 16.3 0.0 2.5 2 0 0 2 2 2 2 CBS domain DnaJ PF00226.31 ORY11919.1 - 1.4e-18 66.7 0.0 3e-18 65.7 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain Homez PF11569.8 ORY11919.1 - 0.09 12.3 0.1 0.2 11.1 0.1 1.6 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez zf-3CxxC_2 PF17180.4 ORY11919.1 - 1.5 9.6 6.5 0.27 12.0 1.4 2.5 2 0 0 2 2 2 0 Zinc-binding domain DZR PF12773.7 ORY11919.1 - 2.2 8.4 5.3 7.5 6.7 5.3 1.9 1 1 0 1 1 1 0 Double zinc ribbon ADH_N PF08240.12 ORY11920.1 - 4.6e-25 87.6 0.8 8e-25 86.9 0.8 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORY11920.1 - 8.8e-20 71.0 0.1 5.8e-19 68.4 0.0 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ORY11920.1 - 1.4e-05 26.2 0.0 2.2e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 ORY11920.1 - 0.062 12.6 0.2 0.11 11.8 0.2 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain AMPK1_CBM PF16561.5 ORY11921.1 - 0.00019 21.6 0.1 0.00033 20.8 0.1 1.3 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase DUF1719 PF08224.11 ORY11922.1 - 0.046 12.8 0.0 0.062 12.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1719) MFS_1 PF07690.16 ORY11924.1 - 1.5e-28 99.8 23.7 1.5e-28 99.8 23.7 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily SLATT_6 PF18169.1 ORY11924.1 - 0.93 9.1 2.6 1.1 8.9 0.2 2.0 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 6 DUF4203 PF13886.6 ORY11925.1 - 0.17 11.5 2.7 0.24 11.0 2.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4203) Clr5 PF14420.6 ORY11926.1 - 7.1e-12 45.4 0.7 1.2e-11 44.7 0.7 1.4 1 0 0 1 1 1 1 Clr5 domain Ank_4 PF13637.6 ORY11926.1 - 1.9e-10 41.0 0.2 0.032 14.8 0.0 5.7 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 ORY11926.1 - 4.1e-09 36.9 0.0 0.0001 22.8 0.0 4.1 4 1 0 4 4 4 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ORY11926.1 - 1.4e-07 31.2 0.7 0.17 12.5 0.0 6.1 6 0 0 6 6 6 1 Ankyrin repeat Ank PF00023.30 ORY11926.1 - 2.1e-06 27.9 2.5 5.5 7.6 0.0 6.2 6 0 0 6 6 6 2 Ankyrin repeat Ank_5 PF13857.6 ORY11926.1 - 0.014 15.7 1.4 19 5.7 0.0 4.4 2 2 2 4 4 4 0 Ankyrin repeats (many copies) Peroxidase_2 PF01328.17 ORY11927.1 - 1.8e-45 155.8 0.0 2.4e-45 155.4 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 DUF4690 PF15756.5 ORY11928.1 - 0.0038 17.8 0.1 0.01 16.4 0.1 1.8 1 0 0 1 1 1 1 Small Novel Rich in Cartilage Amnionless PF14828.6 ORY11928.1 - 0.065 12.1 0.0 0.087 11.6 0.0 1.2 1 0 0 1 1 1 0 Amnionless Syndecan PF01034.20 ORY11928.1 - 0.4 10.6 1.5 0.73 9.8 1.5 1.4 1 0 0 1 1 1 0 Syndecan domain Clr5 PF14420.6 ORY11932.1 - 1.7e-14 53.8 1.8 9.3e-14 51.4 1.1 2.4 3 0 0 3 3 3 1 Clr5 domain Ank_3 PF13606.6 ORY11932.1 - 7.8e-11 41.2 0.9 0.0017 18.7 0.1 6.5 7 0 0 7 7 7 2 Ankyrin repeat Ank_4 PF13637.6 ORY11932.1 - 1.9e-08 34.7 1.9 0.016 15.8 0.2 5.4 5 0 0 5 5 5 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 ORY11932.1 - 1.9e-07 31.5 0.0 0.077 13.6 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeats (3 copies) Ank PF00023.30 ORY11932.1 - 4.9e-07 29.9 1.0 0.021 15.2 0.1 3.7 3 0 0 3 3 3 2 Ankyrin repeat zf-C2H2_4 PF13894.6 ORY11932.1 - 1.1e-05 25.8 4.4 0.29 12.1 0.8 4.2 3 0 0 3 3 3 2 C2H2-type zinc finger Ank_5 PF13857.6 ORY11932.1 - 0.00099 19.4 1.5 3.1 8.2 0.1 3.8 3 0 0 3 3 3 2 Ankyrin repeats (many copies) zf-C2H2 PF00096.26 ORY11932.1 - 0.68 10.5 11.9 2.2 8.9 0.7 4.1 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-met PF12874.7 ORY11932.1 - 1.5 9.3 9.8 2 8.9 0.0 3.6 4 0 0 4 4 4 0 Zinc-finger of C2H2 type CoA_transf_3 PF02515.17 ORY11934.1 - 8.1e-47 160.1 0.1 1.7e-45 155.8 0.0 2.2 2 0 0 2 2 2 2 CoA-transferase family III IlvGEDA_leader PF08046.11 ORY11937.1 - 0.17 11.3 0.2 0.28 10.7 0.2 1.3 1 0 0 1 1 1 0 IlvGEDA operon leader peptide Acyl-CoA_dh_2 PF08028.11 ORY11940.1 - 2.8e-12 47.1 0.4 4.4e-12 46.4 0.4 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 ORY11940.1 - 0.00023 21.3 0.1 0.0014 18.7 0.0 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 ORY11940.1 - 0.00046 20.8 0.0 0.00084 20.0 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 ORY11940.1 - 0.011 16.0 1.0 0.018 15.2 0.2 1.9 2 1 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain DUF3311 PF11755.8 ORY11940.1 - 0.13 12.2 0.4 2.2 8.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3311) Gpr1_Fun34_YaaH PF01184.19 ORY11941.1 - 1.5e-35 122.7 22.1 1.8e-35 122.4 22.1 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Abhydrolase_3 PF07859.13 ORY11944.1 - 8.7e-26 91.1 0.0 1.3e-25 90.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 ORY11944.1 - 2.7e-22 79.2 0.0 3.6e-22 78.7 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase zf-RING_6 PF14835.6 ORY11945.1 - 0.57 10.1 4.3 1.1 9.2 4.3 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-C3HC4_3 PF13920.6 ORY11945.1 - 4.3 7.3 10.2 7.2 6.6 10.2 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF5384 PF17358.2 ORY11966.1 - 0.26 11.3 7.2 0.48 10.5 7.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5384) Transferase PF02458.15 ORY11968.1 - 0.00043 19.0 0.0 0.034 12.8 0.0 2.1 2 0 0 2 2 2 2 Transferase family Lactamase_B PF00753.27 ORY11971.1 - 0.003 17.6 0.3 0.035 14.1 0.0 2.2 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 ORY11971.1 - 0.082 12.4 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Lactamase_B_6 PF16661.5 ORY11971.1 - 0.093 12.2 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily domain DUF2855 PF11017.8 ORY11972.1 - 8.4e-78 262.5 0.0 9.6e-78 262.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2855) S-methyl_trans PF02574.16 ORY11973.1 - 1e-63 215.7 0.0 1.2e-63 215.5 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase WD40 PF00400.32 ORY11974.1 - 9.4e-45 149.7 23.6 7.5e-09 36.1 0.1 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIID_NTD2 PF04494.15 ORY11974.1 - 1e-35 122.8 0.4 1.4e-35 122.3 0.4 1.2 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain ANAPC4_WD40 PF12894.7 ORY11974.1 - 5.1e-11 42.7 0.4 0.069 13.4 0.1 5.1 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 ORY11974.1 - 0.0031 16.5 0.1 3 6.7 0.0 3.4 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 ORY11974.1 - 0.011 14.4 6.1 4.8 5.7 0.0 3.9 4 1 1 5 5 5 0 Nucleoporin Nup120/160 eIF2A PF08662.11 ORY11974.1 - 0.1 12.4 0.0 0.34 10.8 0.0 1.8 1 1 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A RAB3GAP2_N PF14655.6 ORY11974.1 - 0.11 11.7 0.0 3.9 6.6 0.0 2.2 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF2283 PF10049.9 ORY11974.1 - 0.38 11.0 1.0 0.76 10.1 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2283) Med11 PF10280.9 ORY11975.1 - 3.5e-12 47.0 0.0 6.4e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 Mediator complex protein HORMA PF02301.18 ORY11975.1 - 0.1 12.1 1.0 0.14 11.7 1.0 1.1 1 0 0 1 1 1 0 HORMA domain Flavin_Reduct PF01613.18 ORY11976.1 - 2.2e-20 73.3 0.0 3.5e-20 72.6 0.0 1.3 1 0 0 1 1 1 1 Flavin reductase like domain Prothymosin PF03247.14 ORY11976.1 - 2.6 8.5 16.7 2.7 8.5 5.6 2.4 2 0 0 2 2 2 0 Prothymosin/parathymosin family Ribosomal_L31 PF01197.18 ORY11977.1 - 0.00076 19.7 0.0 0.0013 18.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L31 PLC-beta_C PF08703.10 ORY11978.1 - 0.097 12.6 0.3 0.097 12.6 0.3 1.8 2 0 0 2 2 2 0 PLC-beta C terminal DAO PF01266.24 ORY11979.1 - 1.5e-32 113.6 0.0 2.1e-32 113.1 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase ThiF PF00899.21 ORY11979.1 - 6.7e-05 22.4 0.1 0.00015 21.2 0.1 1.5 1 0 0 1 1 1 1 ThiF family NAD_binding_8 PF13450.6 ORY11979.1 - 0.0045 17.2 0.1 0.013 15.7 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ORY11979.1 - 0.0071 15.6 0.0 0.022 14.0 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 ORY11979.1 - 0.022 14.8 0.0 0.037 14.1 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_Gly3P_dh_N PF01210.23 ORY11979.1 - 0.027 14.4 0.4 0.087 12.8 0.3 1.7 1 1 1 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GIDA PF01134.22 ORY11979.1 - 0.048 12.7 0.0 0.29 10.2 0.0 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox PF00070.27 ORY11979.1 - 0.058 14.0 0.0 0.21 12.2 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ORY11979.1 - 0.11 11.5 0.0 0.29 10.2 0.0 1.7 2 0 0 2 2 2 0 FAD binding domain 3HCDH_N PF02737.18 ORY11979.1 - 0.15 11.9 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SMC_N PF02463.19 ORY11980.1 - 1.1e-76 257.1 0.0 2.2e-76 256.1 0.0 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 ORY11980.1 - 4.9e-25 88.1 0.0 1.7e-24 86.4 0.0 2.0 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 ORY11980.1 - 1.2e-11 45.0 2.6 4.2e-05 23.5 0.0 3.4 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 ORY11980.1 - 0.00044 19.9 0.0 0.00091 18.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Myosin_tail_1 PF01576.19 ORY11980.1 - 0.0007 17.5 48.3 0.0007 17.5 48.3 4.4 2 2 2 4 4 4 2 Myosin tail DivIC PF04977.15 ORY11980.1 - 0.0044 16.8 0.7 0.0044 16.8 0.7 9.9 5 2 5 10 10 10 1 Septum formation initiator ABC_tran PF00005.27 ORY11980.1 - 1.7 9.1 0.0 1.7 9.1 0.0 6.6 4 1 0 5 5 5 0 ABC transporter Tfb5 PF06331.12 ORY11980.1 - 3.1 7.8 5.3 1.6 8.7 0.3 3.3 3 0 0 3 3 3 0 Transcription factor TFIIH complex subunit Tfb5 p450 PF00067.22 ORY11981.1 - 5.6e-52 177.0 0.0 7.8e-52 176.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF4984 PF16372.5 ORY11981.1 - 0.15 11.9 0.0 0.29 11.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4984) Ribosomal_S27 PF01599.19 ORY11981.1 - 0.44 10.7 1.8 0.85 9.8 1.8 1.4 1 0 0 1 1 1 0 Ribosomal protein S27a Pyridoxal_deC PF00282.19 ORY11983.1 - 1.3e-27 96.6 0.0 2.9e-27 95.4 0.0 1.5 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 ORY11983.1 - 0.0049 16.2 0.0 0.0063 15.8 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 ORY11983.1 - 0.066 12.2 0.0 0.13 11.2 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class-V HTH_Tnp_IS1 PF12759.7 ORY11983.1 - 0.15 11.7 0.0 0.35 10.5 0.0 1.5 1 0 0 1 1 1 0 InsA C-terminal domain Helicase_C PF00271.31 ORY11984.1 - 2.8e-20 72.7 0.0 2.4e-17 63.3 0.0 2.8 2 0 0 2 2 2 2 Helicase conserved C-terminal domain DEAD PF00270.29 ORY11984.1 - 6.4e-19 68.4 0.0 1.4e-18 67.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 ORY11984.1 - 1e-17 64.6 7.2 4e-17 62.7 7.2 2.2 1 0 0 1 1 1 1 RecQ zinc-binding RQC PF09382.10 ORY11984.1 - 5.8e-14 51.9 0.2 1.2e-13 50.8 0.2 1.5 1 0 0 1 1 1 1 RQC domain HRDC PF00570.23 ORY11984.1 - 4.9e-07 29.6 0.0 1.7e-06 27.9 0.0 1.9 1 0 0 1 1 1 1 HRDC domain ResIII PF04851.15 ORY11984.1 - 9.2e-06 25.8 0.0 2.4e-05 24.4 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit MR_MLE_C PF13378.6 ORY11984.1 - 0.026 14.1 0.0 0.061 12.9 0.0 1.5 1 0 0 1 1 1 0 Enolase C-terminal domain-like DUF3287 PF11690.8 ORY11984.1 - 0.091 12.5 0.6 2.3 8.0 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3287) PIP5K PF01504.18 ORY11985.1 - 1.9e-102 342.2 1.4 2.4e-102 341.9 0.2 1.8 2 0 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase Linker_histone PF00538.19 ORY11986.1 - 5.8e-27 93.9 0.2 5.8e-27 93.9 0.2 1.7 2 0 0 2 2 2 1 linker histone H1 and H5 family AAA PF00004.29 ORY11987.1 - 2.4e-45 154.2 0.5 5.6e-45 153.0 0.0 1.9 3 0 0 3 3 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 ORY11987.1 - 6.2e-10 38.9 0.1 4e-09 36.3 0.0 2.2 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 ORY11987.1 - 9.3e-09 35.4 0.1 3.1e-08 33.7 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 ORY11987.1 - 6.4e-08 32.9 0.0 1.4e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 ORY11987.1 - 1.1e-07 32.4 0.1 3.5e-05 24.3 0.0 3.0 2 1 1 3 3 3 1 AAA ATPase domain DUF815 PF05673.13 ORY11987.1 - 4.8e-06 25.9 0.2 1.1e-05 24.8 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 ORY11987.1 - 4.7e-05 23.7 1.4 0.0081 16.4 0.1 2.6 1 1 0 2 2 2 1 AAA domain AAA_lid_3 PF17862.1 ORY11987.1 - 0.00029 20.6 0.0 0.00066 19.4 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 ORY11987.1 - 0.00032 20.5 0.0 0.00091 19.0 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 ORY11987.1 - 0.00057 20.4 0.0 0.0014 19.1 0.0 1.7 2 0 0 2 2 1 1 AAA domain RNA_helicase PF00910.22 ORY11987.1 - 0.00078 19.8 0.0 0.0017 18.7 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_28 PF13521.6 ORY11987.1 - 0.001 19.3 0.0 0.0021 18.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 ORY11987.1 - 0.0013 18.1 0.0 0.0024 17.1 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain TsaE PF02367.17 ORY11987.1 - 0.0015 18.5 0.0 0.022 14.7 0.0 2.2 1 1 1 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 ORY11987.1 - 0.0019 17.8 0.1 0.0096 15.4 0.1 2.0 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_14 PF13173.6 ORY11987.1 - 0.0019 18.2 0.1 0.0069 16.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 ORY11987.1 - 0.0028 17.6 0.0 0.014 15.3 0.0 2.1 2 0 0 2 2 2 1 NTPase AAA_30 PF13604.6 ORY11987.1 - 0.0053 16.5 0.1 0.013 15.2 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 ORY11987.1 - 0.006 16.7 0.0 0.02 15.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.11 ORY11987.1 - 0.0066 16.3 0.0 0.02 14.8 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 ORY11987.1 - 0.0084 15.5 0.0 0.019 14.3 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI NACHT PF05729.12 ORY11987.1 - 0.0091 15.9 0.1 0.11 12.4 0.0 2.5 2 0 0 2 2 2 1 NACHT domain TniB PF05621.11 ORY11987.1 - 0.0091 15.4 0.0 0.54 9.6 0.0 2.3 2 0 0 2 2 2 1 Bacterial TniB protein IstB_IS21 PF01695.17 ORY11987.1 - 0.017 14.9 0.1 0.044 13.5 0.0 1.8 2 0 0 2 2 1 0 IstB-like ATP binding protein AAA_24 PF13479.6 ORY11987.1 - 0.018 14.8 0.2 0.046 13.4 0.2 1.7 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 ORY11987.1 - 0.035 14.0 0.8 0.22 11.4 0.1 2.5 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea ATPase PF06745.13 ORY11987.1 - 0.038 13.3 1.6 0.56 9.5 0.0 2.6 3 0 0 3 3 3 0 KaiC AAA_25 PF13481.6 ORY11987.1 - 0.043 13.4 0.9 0.26 10.9 0.1 2.3 2 1 1 3 3 3 0 AAA domain AAA_11 PF13086.6 ORY11987.1 - 0.049 13.4 0.1 0.14 11.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain Viral_Hsp90 PF03225.14 ORY11987.1 - 0.057 11.9 0.0 0.09 11.3 0.0 1.2 1 0 0 1 1 1 0 Viral heat shock protein Hsp90 homologue Bac_DnaA PF00308.18 ORY11987.1 - 0.065 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Bacterial dnaA protein Sigma54_activat PF00158.26 ORY11987.1 - 0.077 12.7 0.2 1.4 8.6 0.0 2.5 2 1 0 2 2 2 0 Sigma-54 interaction domain AFG1_ATPase PF03969.16 ORY11987.1 - 0.087 11.7 0.3 0.16 10.9 0.0 1.5 2 0 0 2 2 2 0 AFG1-like ATPase AAA_19 PF13245.6 ORY11987.1 - 0.14 12.5 0.1 0.41 11.0 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 ORY11987.1 - 0.18 11.6 0.0 0.35 10.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Parvo_NS1 PF01057.17 ORY11987.1 - 0.21 10.7 0.0 0.39 9.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ARID PF01388.21 ORY11989.1 - 1.7e-13 51.0 3.1 4.7e-13 49.6 0.0 3.0 3 0 0 3 3 3 1 ARID/BRIGHT DNA binding domain BAF250_C PF12031.8 ORY11989.1 - 2.6 7.3 11.5 0.11 11.8 0.3 2.9 3 0 0 3 3 3 0 SWI/SNF-like complex subunit BAF250/Osa Eapp_C PF10238.9 ORY11989.1 - 2.7 8.1 14.1 7.7 6.6 14.1 1.8 1 0 0 1 1 1 0 E2F-associated phosphoprotein Tau95 PF09734.9 ORY11989.1 - 4.7 8.0 18.6 1.6 9.6 12.1 3.0 2 1 0 2 2 2 0 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain HET PF06985.11 ORY11990.1 - 1.4e-29 103.3 0.0 2.4e-29 102.6 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) RPAP1_C PF08620.10 ORY11992.1 - 3.7e-27 94.2 0.1 7.5e-27 93.2 0.1 1.6 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.10 ORY11992.1 - 2.8e-18 65.4 8.0 5.2e-18 64.5 8.0 1.5 1 0 0 1 1 1 1 RPAP1-like, N-terminal DUF4085 PF13315.6 ORY11992.1 - 0.058 13.0 0.3 0.088 12.4 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4085) UDG PF03167.19 ORY11993.1 - 1.3e-21 77.2 0.1 2.6e-21 76.3 0.0 1.4 2 0 0 2 2 2 1 Uracil DNA glycosylase superfamily NuDC PF16273.5 ORY11993.1 - 0.097 13.2 0.8 0.22 12.1 0.8 1.6 1 0 0 1 1 1 0 Nuclear distribution C domain KGG PF10685.9 ORY11994.1 - 8.4e-12 45.0 9.2 5.9e-09 35.9 0.1 3.3 3 0 0 3 3 3 2 Stress-induced bacterial acidophilic repeat motif Methyltransf_23 PF13489.6 ORY11996.1 - 1.4e-15 57.5 0.0 2.2e-15 56.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY11996.1 - 8e-08 32.9 0.0 1.8e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY11996.1 - 2.5e-05 25.0 0.0 6.2e-05 23.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY11996.1 - 3.1e-05 23.8 0.0 0.00013 21.8 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY11996.1 - 6.9e-05 23.4 0.0 0.00021 21.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 ORY11996.1 - 0.0023 18.1 0.0 0.0035 17.5 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_4 PF02390.17 ORY11996.1 - 0.017 14.6 0.0 0.036 13.5 0.0 1.6 1 1 0 1 1 1 0 Putative methyltransferase MTS PF05175.14 ORY11996.1 - 0.025 14.1 0.0 0.059 12.9 0.0 1.5 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_2 PF00891.18 ORY11996.1 - 0.026 13.8 0.0 0.042 13.1 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Ubie_methyltran PF01209.18 ORY11996.1 - 0.079 12.3 0.0 0.61 9.4 0.0 2.1 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family MFS_1 PF07690.16 ORY11997.1 - 4.8e-28 98.1 19.8 4.8e-28 98.1 19.8 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF3040 PF11239.8 ORY11997.1 - 7.7 6.9 6.9 11 6.4 0.4 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) Helo_like_N PF17111.5 ORY11998.1 - 5e-11 42.4 0.8 7.8e-11 41.7 0.8 1.3 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins Transcrip_act PF04949.13 ORY11998.1 - 0.015 15.2 0.7 0.027 14.3 0.7 1.5 1 1 0 1 1 1 0 Transcriptional activator Chordopox_A13L PF05961.11 ORY11998.1 - 0.017 15.4 0.0 0.045 14.0 0.0 1.7 1 0 0 1 1 1 0 Chordopoxvirus A13L protein Borrelia_REV PF03978.13 ORY11998.1 - 0.022 14.7 3.0 0.045 13.7 2.9 1.7 1 1 0 1 1 1 0 Borrelia burgdorferi REV protein Kazal_3 PF18434.1 ORY11998.1 - 0.028 14.2 0.1 0.072 12.9 0.1 1.7 1 0 0 1 1 1 0 Kazal-type serine protease inhibitor domain CspB_prodomain PF18425.1 ORY11998.1 - 0.053 13.5 0.3 0.12 12.3 0.1 1.7 2 0 0 2 2 2 0 Csp protease B prodomain DUF1664 PF07889.12 ORY11998.1 - 0.07 13.2 5.0 1.5 8.8 1.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Corona_nucleoca PF00937.18 ORY11998.1 - 0.072 12.1 0.0 0.096 11.7 0.0 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Fib_alpha PF08702.10 ORY11998.1 - 0.19 11.9 4.4 0.26 11.5 4.4 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Cyclase_polyket PF04673.12 ORY11999.1 - 0.11 12.8 0.0 3.4 8.0 0.0 2.0 1 1 1 2 2 2 0 Polyketide synthesis cyclase Lactamase_B PF00753.27 ORY12000.1 - 4e-06 27.0 2.0 0.00057 20.0 0.4 2.5 2 1 0 2 2 2 2 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 ORY12000.1 - 0.00049 19.7 0.2 0.0014 18.2 0.0 1.8 2 0 0 2 2 2 1 Beta-lactamase superfamily domain NAD_binding_6 PF08030.12 ORY12001.1 - 2.7e-33 115.3 0.0 4.4e-33 114.6 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 ORY12001.1 - 5.6e-21 74.7 0.0 1.4e-20 73.4 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 ORY12001.1 - 1.3e-18 67.3 12.3 1.3e-18 67.3 12.3 2.4 1 1 1 2 2 2 1 Ferric reductase like transmembrane component Adeno_E1B_19K PF01691.16 ORY12001.1 - 0.059 12.9 0.2 0.15 11.6 0.1 1.7 2 0 0 2 2 2 0 Adenovirus E1B 19K protein / small t-antigen NAD_binding_1 PF00175.21 ORY12001.1 - 0.075 13.7 0.0 0.32 11.6 0.0 2.1 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 ORY12001.1 - 0.16 12.3 0.0 0.38 11.1 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain adh_short_C2 PF13561.6 ORY12002.1 - 2.4e-54 184.4 0.5 3e-54 184.1 0.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY12002.1 - 6.6e-46 156.2 0.2 1.1e-45 155.5 0.1 1.4 1 1 1 2 2 2 1 short chain dehydrogenase KR PF08659.10 ORY12002.1 - 3.6e-14 53.1 0.3 6.7e-14 52.2 0.1 1.4 1 1 1 2 2 2 1 KR domain THF_DHG_CYH_C PF02882.19 ORY12002.1 - 0.019 14.3 0.2 0.046 13.0 0.0 1.7 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DFP PF04127.15 ORY12002.1 - 0.021 14.7 0.9 0.079 12.8 0.2 2.1 2 1 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein 3HCDH_N PF02737.18 ORY12002.1 - 0.051 13.5 0.4 0.26 11.2 0.1 2.0 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain EMG1 PF03587.14 ORY12004.1 - 1.5e-77 259.6 0.0 1.8e-77 259.4 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase Plk4_PB2 PF18409.1 ORY12004.1 - 0.08 13.6 0.0 0.13 13.0 0.0 1.3 1 0 0 1 1 1 0 Polo-like Kinase 4 Polo Box 2 DUF3168 PF11367.8 ORY12005.1 - 0.13 12.5 6.9 1.2 9.3 0.1 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3168) Gly-zipper_Omp PF13488.6 ORY12005.1 - 0.17 11.9 5.9 0.22 11.5 3.5 2.3 2 0 0 2 2 2 0 Glycine zipper Rick_17kDa_Anti PF05433.15 ORY12005.1 - 1.6 8.7 9.2 0.71 9.8 5.6 2.1 2 0 0 2 2 2 0 Glycine zipper 2TM domain Pyridoxal_deC PF00282.19 ORY12006.1 - 2.9e-31 108.5 0.0 2.6e-22 79.1 0.0 3.0 3 0 0 3 3 3 3 Pyridoxal-dependent decarboxylase conserved domain PUF PF00806.19 ORY12007.1 - 4.5e-14 51.2 0.0 1.7 8.5 0.0 7.6 8 0 0 8 8 8 6 Pumilio-family RNA binding repeat TetR_C_16 PF17920.1 ORY12007.1 - 0.048 13.9 0.1 2 8.7 0.0 2.7 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain RINT1_TIP1 PF04437.13 ORY12008.1 - 3.4e-176 587.0 0.0 2.8e-175 584.0 0.0 1.9 2 0 0 2 2 2 1 RINT-1 / TIP-1 family CRISPR_Cse2 PF09485.10 ORY12008.1 - 0.04 14.5 8.9 0.075 13.6 7.5 2.2 1 1 0 1 1 1 0 CRISPR-associated protein Cse2 (CRISPR_cse2) RasGAP_C PF03836.15 ORY12008.1 - 0.053 13.7 1.8 0.13 12.4 1.8 1.6 1 0 0 1 1 1 0 RasGAP C-terminus Prp19 PF08606.11 ORY12008.1 - 0.065 13.2 2.6 2.9 8.0 1.0 2.9 2 0 0 2 2 2 0 Prp19/Pso4-like TBCC_N PF16752.5 ORY12008.1 - 0.24 11.9 7.6 0.6 10.6 6.5 2.3 2 1 0 2 2 2 0 Tubulin-specific chaperone C N-terminal domain DUF724 PF05266.14 ORY12008.1 - 0.27 11.0 1.8 0.65 9.8 1.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Nup54 PF13874.6 ORY12008.1 - 0.29 11.2 9.7 1.6 8.8 4.7 2.6 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 TMP_2 PF06791.13 ORY12008.1 - 0.68 9.6 3.5 20 4.8 0.1 2.7 2 0 0 2 2 2 0 Prophage tail length tape measure protein BST2 PF16716.5 ORY12008.1 - 0.98 10.1 8.0 0.17 12.5 3.1 2.2 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 DUF4763 PF15960.5 ORY12008.1 - 2.5 7.3 11.9 0.93 8.7 9.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4763) CLZ PF16526.5 ORY12008.1 - 6.2 7.3 16.9 11 6.4 2.1 4.7 5 0 0 5 5 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ANAPC2 PF08672.11 ORY12009.1 - 3.4e-16 59.5 1.4 1e-15 57.9 1.4 1.9 1 0 0 1 1 1 1 Anaphase promoting complex (APC) subunit 2 Cullin PF00888.22 ORY12009.1 - 4.7e-13 48.6 0.0 8.4e-13 47.8 0.0 1.4 1 0 0 1 1 1 1 Cullin family FeoC PF09012.10 ORY12009.1 - 0.046 13.8 0.1 2.9 8.0 0.0 2.7 2 0 0 2 2 2 0 FeoC like transcriptional regulator Ank_2 PF12796.7 ORY12010.1 - 1.9e-19 70.0 0.0 1.8e-05 25.2 0.1 3.3 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 ORY12010.1 - 1.7e-18 66.1 0.1 0.016 15.7 0.1 5.3 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.6 ORY12010.1 - 2.4e-18 66.3 1.1 3.5e-05 24.3 0.0 4.9 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY12010.1 - 6.7e-14 50.6 1.9 0.014 15.9 0.1 5.8 6 1 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 ORY12010.1 - 1e-11 44.8 0.1 0.01 16.1 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Helo_like_N PF17111.5 ORY12010.1 - 0.002 17.5 0.1 0.0033 16.8 0.1 1.3 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins SesA PF17107.5 ORY12010.1 - 0.024 14.8 0.2 0.04 14.1 0.2 1.4 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases BLOC1_2 PF10046.9 ORY12010.1 - 0.068 13.5 0.5 1.9 8.9 0.1 2.5 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ADH_zinc_N PF00107.26 ORY12011.1 - 3.4e-16 59.4 0.1 5.9e-16 58.6 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ORY12011.1 - 7.4e-08 32.3 0.0 2.3e-07 30.7 0.0 1.9 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 ORY12011.1 - 1.3e-07 32.7 0.0 2.4e-07 31.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF3206 PF11472.8 ORY12011.1 - 0.15 12.1 0.0 1.1 9.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3206) DASH_Dam1 PF08653.10 ORY12012.1 - 4.9e-27 93.5 1.5 7.5e-27 92.9 1.5 1.3 1 0 0 1 1 1 1 DASH complex subunit Dam1 CRAL_TRIO PF00650.20 ORY12013.1 - 4.1e-45 153.3 0.0 8.3e-45 152.3 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 ORY12013.1 - 9.6e-16 57.7 0.4 2.2e-15 56.6 0.4 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 ORY12013.1 - 3.9e-07 30.3 0.0 6.6e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain PY_rept_46 PF09689.10 ORY12013.1 - 0.029 14.9 2.2 0.029 14.9 2.2 2.1 2 0 0 2 2 2 0 Plasmodium yoelii repeat (PY_rept_46) Ytp1 PF10355.9 ORY12014.1 - 3.8e-118 393.7 11.4 3.8e-118 393.7 11.4 1.6 2 0 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 ORY12014.1 - 1.6e-28 98.6 6.0 1.6e-28 98.6 6.0 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) PDR_CDR PF06422.12 ORY12014.1 - 2.4 8.1 4.5 3.5 7.6 0.3 2.9 3 0 0 3 3 3 0 CDR ABC transporter ADH_zinc_N_2 PF13602.6 ORY12015.1 - 4.4e-25 89.3 0.0 8.1e-25 88.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 ORY12015.1 - 2.4e-19 69.6 0.1 6.5e-19 68.2 0.1 1.7 2 1 0 2 2 2 1 Zinc-binding dehydrogenase GST_N_3 PF13417.6 ORY12016.1 - 3.4e-20 72.2 0.1 6.7e-20 71.3 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 ORY12016.1 - 1.5e-19 70.0 0.6 3.8e-19 68.7 0.1 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 ORY12016.1 - 7.4e-11 42.3 0.4 1.8e-10 41.0 0.3 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 ORY12016.1 - 7.6e-07 29.1 0.1 2e-06 27.7 0.1 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 ORY12016.1 - 0.0029 18.2 0.0 0.0051 17.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 ORY12016.1 - 0.0042 17.3 0.0 0.0085 16.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 ORY12016.1 - 0.12 12.6 0.0 0.34 11.1 0.0 1.8 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain MFS_1 PF07690.16 ORY12018.1 - 1.3e-45 155.8 37.8 1.3e-45 155.8 37.8 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY12018.1 - 6e-06 25.4 41.7 0.0012 17.8 41.5 3.1 1 1 0 1 1 1 1 Sugar (and other) transporter BNIP3 PF06553.12 ORY12018.1 - 0.055 13.1 1.7 0.086 12.5 1.7 1.2 1 0 0 1 1 1 0 BNIP3 ADH_zinc_N PF00107.26 ORY12019.1 - 3e-11 43.4 0.0 6.2e-11 42.4 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ORY12019.1 - 2.5e-08 35.1 0.1 1e-07 33.0 0.1 2.0 1 1 0 1 1 1 1 Zinc-binding dehydrogenase DUF2855 PF11017.8 ORY12019.1 - 5.4e-05 23.1 0.0 7.7e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2855) ADH_N PF08240.12 ORY12019.1 - 0.0083 16.0 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain RPT PF13446.6 ORY12020.1 - 1.9e-40 136.6 6.4 4.8e-18 64.8 0.0 4.9 5 0 0 5 5 5 4 A repeated domain in UCH-protein UCH PF00443.29 ORY12020.1 - 2.2e-34 119.1 0.0 6.4e-34 117.6 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 ORY12020.1 - 0.00082 19.1 0.3 0.035 13.7 0.0 3.0 4 0 0 4 4 4 1 Ubiquitin carboxyl-terminal hydrolase Rdx PF10262.9 ORY12020.1 - 0.012 15.8 0.1 1.1 9.4 0.0 2.7 2 0 0 2 2 2 0 Rdx family DUF3209 PF11483.8 ORY12020.1 - 0.35 11.4 5.3 0.22 12.0 1.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3209) CAP_N PF01213.19 ORY12020.1 - 0.82 9.1 3.9 2.1 7.7 3.9 1.6 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal E7 PF00527.18 ORY12020.1 - 5.8 7.2 7.6 14 6.0 0.0 4.1 5 0 0 5 5 5 0 E7 protein, Early protein Tim17 PF02466.19 ORY12021.1 - 1.2e-06 28.8 8.3 6.6e-06 26.5 8.1 2.1 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family TBCC PF07986.12 ORY12022.1 - 4.8e-31 107.0 0.9 6.9e-31 106.5 0.1 1.7 2 0 0 2 2 2 1 Tubulin binding cofactor C TBCC_N PF16752.5 ORY12022.1 - 2.7e-09 37.5 1.1 2.9e-09 37.4 0.1 1.6 2 0 0 2 2 2 1 Tubulin-specific chaperone C N-terminal domain HCV_env PF01539.17 ORY12022.1 - 0.025 14.3 0.7 0.041 13.6 0.7 1.3 1 0 0 1 1 1 0 Hepatitis C virus envelope glycoprotein E1 HeLo PF14479.6 ORY12023.1 - 3e-23 82.8 0.2 4.5e-23 82.2 0.2 1.2 1 0 0 1 1 1 1 Prion-inhibition and propagation Pkinase_Tyr PF07714.17 ORY12023.1 - 0.00018 20.9 0.1 0.0019 17.6 0.1 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 ORY12023.1 - 0.069 12.5 0.1 0.46 9.8 0.1 2.1 1 1 0 1 1 1 0 Protein kinase domain Ank_2 PF12796.7 ORY12024.1 - 5.7e-21 74.9 0.0 0.0059 17.2 0.0 6.7 6 1 1 7 7 7 5 Ankyrin repeats (3 copies) Pkinase PF00069.25 ORY12024.1 - 2.1e-20 73.2 0.0 3.6e-20 72.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY12024.1 - 2e-18 66.6 0.0 3.4e-18 65.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_3 PF13606.6 ORY12024.1 - 4.6e-11 41.9 4.5 0.036 14.6 0.0 7.3 7 0 0 7 7 7 3 Ankyrin repeat Ank_4 PF13637.6 ORY12024.1 - 1e-10 41.9 0.3 0.0047 17.5 0.0 6.6 5 1 1 6 6 6 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 ORY12024.1 - 3.9e-10 39.8 2.6 0.0013 18.9 0.0 5.9 5 1 1 6 6 6 2 Ankyrin repeats (many copies) Ank PF00023.30 ORY12024.1 - 7.8e-08 32.4 8.9 0.7 10.4 0.0 8.3 9 1 0 9 9 9 2 Ankyrin repeat HET PF06985.11 ORY12025.1 - 1.5e-26 93.5 0.7 2.3e-26 92.9 0.7 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ribosomal_S2 PF00318.20 ORY12026.1 - 3.9e-67 225.6 1.4 1e-65 221.0 0.7 2.6 2 1 0 2 2 2 1 Ribosomal protein S2 PAS_9 PF13426.7 ORY12027.1 - 8.5e-27 93.4 0.0 1e-16 61.1 0.0 3.7 3 0 0 3 3 3 3 PAS domain PAS_3 PF08447.12 ORY12027.1 - 4.2e-18 65.4 0.0 6.3e-11 42.4 0.0 3.7 4 0 0 4 4 4 3 PAS fold GATA PF00320.27 ORY12027.1 - 6e-15 54.6 9.5 1.2e-14 53.6 9.5 1.5 1 0 0 1 1 1 1 GATA zinc finger PAS PF00989.25 ORY12027.1 - 2.1e-12 47.0 0.0 3.2e-05 23.9 0.0 3.6 3 0 0 3 3 3 3 PAS fold PAS_11 PF14598.6 ORY12027.1 - 7.7e-08 32.5 0.0 0.0012 19.0 0.0 2.6 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.10 ORY12027.1 - 0.00065 19.9 0.0 0.23 11.7 0.0 2.9 3 0 0 3 3 3 1 PAS fold PAS_2 PF08446.11 ORY12027.1 - 0.0039 17.8 0.0 0.5 11.0 0.0 3.2 3 0 0 3 3 3 1 PAS fold Cytochrom_c3_2 PF14537.6 ORY12027.1 - 0.22 12.0 2.0 0.56 10.7 2.0 1.6 1 0 0 1 1 1 0 Cytochrome c3 Ras PF00071.22 ORY12028.1 - 3.8e-40 137.1 0.0 4.6e-40 136.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY12028.1 - 5.6e-12 45.9 0.0 8.2e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY12028.1 - 4.4e-06 26.3 0.0 5.2e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 ORY12028.1 - 0.0029 17.6 0.0 0.0043 17.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 ORY12028.1 - 0.01 15.4 0.0 0.16 11.5 0.0 2.2 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain NB-ARC PF00931.22 ORY12028.1 - 0.025 13.8 0.0 0.038 13.2 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain PRK PF00485.18 ORY12028.1 - 0.098 12.4 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Flocculin_t3 PF13928.6 ORY12028.1 - 0.18 12.3 0.3 0.4 11.2 0.3 1.5 1 0 0 1 1 1 0 Flocculin type 3 repeat Mito_carr PF00153.27 ORY12029.1 - 1.1e-59 198.4 1.8 4.8e-21 74.5 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein CPSF100_C PF13299.6 ORY12030.1 - 7.2 6.8 9.0 6 7.0 1.1 2.1 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Adenylsucc_synt PF00709.21 ORY12031.1 - 1.4e-171 571.0 0.0 1.6e-171 570.9 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase PBP PF01161.20 ORY12032.1 - 1.6e-14 54.3 0.0 2.2e-14 53.9 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Pkinase PF00069.25 ORY12033.1 - 2.3e-15 56.7 0.0 2.3e-12 46.8 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORY12033.1 - 9.8e-07 28.3 0.0 3.3e-06 26.6 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Pyr_redox_3 PF13738.6 ORY12034.1 - 1.7e-10 40.7 0.0 2.3e-09 37.0 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ORY12034.1 - 3.5e-10 39.5 0.0 1.1e-07 31.4 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 ORY12034.1 - 1.9e-07 30.6 0.0 4.6e-06 26.1 0.0 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 ORY12034.1 - 1.5e-06 27.0 0.0 5.3e-05 21.8 0.0 2.1 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 ORY12034.1 - 2.6e-06 27.5 0.3 6.2e-05 23.2 0.0 3.0 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ORY12034.1 - 0.0061 16.2 1.2 0.76 9.3 0.0 3.0 4 1 0 4 4 4 1 FAD dependent oxidoreductase Thi4 PF01946.17 ORY12034.1 - 0.0067 15.7 0.1 0.02 14.1 0.0 1.7 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.27 ORY12034.1 - 0.01 16.4 0.0 0.24 12.0 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ORY12034.1 - 0.01 15.8 0.3 4.6 7.2 0.1 2.9 3 0 0 3 3 3 0 FAD-NAD(P)-binding Mqo PF06039.15 ORY12034.1 - 0.034 12.7 0.1 0.14 10.7 0.0 1.8 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) Lycopene_cycl PF05834.12 ORY12034.1 - 0.11 11.6 0.0 0.2 10.7 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Trp_halogenase PF04820.14 ORY12034.1 - 0.16 10.7 0.7 1.2 7.9 0.1 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Glyco_hydro_49N PF17433.2 ORY12035.1 - 0.047 13.3 0.0 0.056 13.1 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 49 N-terminal Ig-like domain SapB_1 PF05184.15 ORY12036.1 - 0.0031 17.5 0.7 0.0063 16.5 0.7 1.5 1 0 0 1 1 1 1 Saposin-like type B, region 1 Glyoxalase PF00903.25 ORY12037.1 - 9.7e-16 58.1 0.0 2.4e-15 56.9 0.0 1.6 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 ORY12037.1 - 2.2e-07 31.1 0.0 3.7e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Abhydrolase_1 PF00561.20 ORY12039.1 - 1.6e-19 70.6 0.0 1.1e-18 67.8 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 ORY12039.1 - 9e-18 64.3 0.2 3.6e-17 62.3 0.0 2.0 2 0 0 2 2 2 1 TAP-like protein Hydrolase_4 PF12146.8 ORY12039.1 - 0.035 13.4 0.0 0.74 9.0 0.0 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Ank_2 PF12796.7 ORY12040.1 - 6.7e-23 81.1 0.2 3.3e-06 27.6 0.0 6.1 4 2 1 6 6 6 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ORY12040.1 - 8.7e-19 65.7 12.5 0.029 14.9 0.0 9.8 10 0 0 10 10 10 5 Ankyrin repeat Pkinase PF00069.25 ORY12040.1 - 1.8e-17 63.6 0.0 3.3e-17 62.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY12040.1 - 5.3e-16 58.7 0.0 1.5e-15 57.2 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Ank_4 PF13637.6 ORY12040.1 - 4e-15 55.9 6.3 0.025 15.1 0.0 7.8 6 2 1 7 7 7 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 ORY12040.1 - 1.6e-11 44.2 10.9 0.29 11.5 0.1 6.3 5 1 1 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.30 ORY12040.1 - 1.6e-07 31.4 23.0 0.027 14.9 0.0 8.5 9 1 0 9 9 9 2 Ankyrin repeat Kdo PF06293.14 ORY12040.1 - 0.0075 15.6 0.0 0.021 14.2 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family HeLo PF14479.6 ORY12041.1 - 2.2e-22 79.9 0.1 3.7e-22 79.2 0.1 1.3 1 0 0 1 1 1 1 Prion-inhibition and propagation Bclx_interact PF08945.10 ORY12041.1 - 0.054 13.3 0.3 0.13 12.1 0.3 1.6 1 0 0 1 1 1 0 Bcl-x interacting, BH3 domain Pkinase PF00069.25 ORY12041.1 - 0.078 12.3 0.0 0.23 10.8 0.0 1.8 1 1 0 1 1 1 0 Protein kinase domain TPR_12 PF13424.6 ORY12042.1 - 1.9e-82 271.6 56.8 1.1e-14 54.4 0.6 11.9 9 2 3 12 12 12 12 Tetratricopeptide repeat TPR_10 PF13374.6 ORY12042.1 - 2.9e-48 160.5 45.4 2.7e-06 27.1 0.0 18.8 20 0 0 20 20 20 11 Tetratricopeptide repeat TPR_1 PF00515.28 ORY12042.1 - 1.2e-33 113.6 32.9 0.00021 21.0 0.0 15.6 16 0 0 16 16 15 8 Tetratricopeptide repeat TPR_2 PF07719.17 ORY12042.1 - 1.8e-32 108.8 49.0 0.0048 16.9 0.0 18.4 19 0 0 19 19 19 8 Tetratricopeptide repeat TPR_7 PF13176.6 ORY12042.1 - 4e-26 89.1 43.5 0.54 10.4 0.2 17.7 19 0 0 19 19 18 7 Tetratricopeptide repeat TPR_8 PF13181.6 ORY12042.1 - 2.1e-19 68.0 39.9 0.00015 21.7 0.0 15.0 16 0 0 16 16 16 5 Tetratricopeptide repeat TPR_MalT PF17874.1 ORY12042.1 - 1.2e-16 61.0 26.5 4.1e-08 33.0 0.1 6.0 2 1 5 7 7 7 4 MalT-like TPR region TPR_14 PF13428.6 ORY12042.1 - 1.9e-13 50.0 45.3 3 8.9 0.2 16.8 16 3 3 19 19 17 2 Tetratricopeptide repeat TPR_19 PF14559.6 ORY12042.1 - 2.3e-11 44.0 28.5 1 9.9 0.1 12.6 11 3 2 14 14 14 4 Tetratricopeptide repeat TPR_16 PF13432.6 ORY12042.1 - 6.8e-08 33.0 43.3 0.16 12.6 0.1 14.2 16 2 0 17 17 14 2 Tetratricopeptide repeat TPR_11 PF13414.6 ORY12042.1 - 1.7e-07 30.8 21.8 4.2 7.1 0.2 12.1 14 0 0 14 14 14 1 TPR repeat PPR PF01535.20 ORY12042.1 - 4e-07 29.8 5.9 26 5.3 0.0 9.4 10 0 0 10 10 9 0 PPR repeat TPR_6 PF13174.6 ORY12042.1 - 1.1e-05 25.8 41.4 1.5 9.6 0.0 14.2 18 0 0 18 18 13 2 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY12042.1 - 1.6e-05 25.1 28.1 1.6 9.0 0.0 10.6 6 6 2 8 8 8 3 Anaphase-promoting complex, cyclosome, subunit 3 RPN7 PF10602.9 ORY12042.1 - 3e-05 23.8 9.7 2.1 8.0 0.0 7.9 5 3 4 9 9 9 3 26S proteasome subunit RPN7 14-3-3 PF00244.20 ORY12042.1 - 0.0033 17.0 0.0 0.025 14.1 0.0 2.5 1 1 0 1 1 1 1 14-3-3 protein Coatomer_E PF04733.14 ORY12042.1 - 0.0048 16.3 0.3 6.2 6.2 0.0 4.1 2 1 1 3 3 3 1 Coatomer epsilon subunit TPR_4 PF07721.14 ORY12042.1 - 0.034 14.7 22.6 1.5 9.6 0.2 9.6 10 0 0 10 10 9 0 Tetratricopeptide repeat RIC1 PF07064.13 ORY12042.1 - 0.14 11.5 1.4 13 5.1 0.2 2.7 2 0 0 2 2 2 0 RIC1 TPR_20 PF14561.6 ORY12042.1 - 0.62 10.4 15.8 3.2 8.1 0.0 7.7 9 2 2 11 11 9 0 Tetratricopeptide repeat TPR_3 PF07720.12 ORY12042.1 - 0.7 9.9 28.5 1.6 8.8 0.4 7.7 8 0 0 8 8 8 0 Tetratricopeptide repeat Vps39_1 PF10366.9 ORY12042.1 - 6.7 7.0 11.9 5.3 7.4 0.1 5.6 6 1 2 8 8 7 0 Vacuolar sorting protein 39 domain 1 MMR_HSR1 PF01926.23 ORY12043.1 - 8.2e-07 29.1 0.1 3.7e-05 23.8 0.1 2.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 ORY12043.1 - 0.00089 18.6 0.0 1.4 8.2 0.0 2.5 2 0 0 2 2 2 2 AIG1 family AAA_29 PF13555.6 ORY12043.1 - 0.0014 18.3 0.0 0.0033 17.1 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 ORY12043.1 - 0.0016 18.4 0.0 0.012 15.5 0.0 2.5 2 1 0 2 2 2 1 RsgA GTPase IIGP PF05049.13 ORY12043.1 - 0.0017 17.5 0.0 0.041 13.0 0.0 2.4 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) AAA_16 PF13191.6 ORY12043.1 - 0.0017 18.8 0.0 0.012 16.0 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain FtsK_SpoIIIE PF01580.18 ORY12043.1 - 0.0018 17.7 0.0 0.0038 16.6 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family Septin PF00735.18 ORY12043.1 - 0.003 16.9 0.1 0.012 14.9 0.1 1.9 1 1 0 1 1 1 1 Septin GTP_EFTU PF00009.27 ORY12043.1 - 0.013 15.0 0.1 0.061 12.9 0.1 2.2 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_23 PF13476.6 ORY12043.1 - 0.018 15.6 0.0 0.018 15.6 0.0 3.0 2 1 0 2 2 1 0 AAA domain ABC_tran PF00005.27 ORY12043.1 - 0.027 15.0 0.0 0.14 12.7 0.0 2.3 1 0 0 1 1 1 0 ABC transporter T2SSE PF00437.20 ORY12043.1 - 0.042 12.9 0.0 0.084 11.9 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Sigma54_activat PF00158.26 ORY12043.1 - 0.058 13.1 0.0 0.16 11.7 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain RNA_helicase PF00910.22 ORY12043.1 - 0.067 13.6 0.0 0.24 11.8 0.0 2.0 1 0 0 1 1 1 0 RNA helicase AAA_22 PF13401.6 ORY12043.1 - 0.072 13.4 0.0 0.38 11.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 ORY12043.1 - 0.095 12.2 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Dynamin_N PF00350.23 ORY12043.1 - 0.1 12.6 1.9 8 6.5 0.1 3.1 3 0 0 3 3 2 0 Dynamin family DUF87 PF01935.17 ORY12043.1 - 0.12 12.5 0.0 0.48 10.5 0.0 2.0 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_24 PF13479.6 ORY12043.1 - 0.12 12.1 0.0 0.42 10.3 0.0 2.0 1 0 0 1 1 1 0 AAA domain TMEM252 PF15664.5 ORY12043.1 - 3.6 7.3 4.6 1.1 9.0 0.1 2.4 3 0 0 3 3 3 0 Transmembrane protein 252 family CH PF00307.31 ORY12044.1 - 4.2e-08 33.3 0.0 5e-05 23.4 0.0 3.2 3 0 0 3 3 3 2 Calponin homology (CH) domain IQ PF00612.27 ORY12044.1 - 5.2e-05 22.7 13.5 0.018 14.8 0.2 3.9 3 0 0 3 3 3 2 IQ calmodulin-binding motif Sugar_tr PF00083.24 ORY12046.1 - 1.7e-124 416.2 22.6 2e-124 415.9 22.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY12046.1 - 5.2e-23 81.5 60.9 5.7e-21 74.8 29.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4064 PF13273.6 ORY12046.1 - 1.9 8.8 14.2 4.9 7.5 3.7 4.5 4 1 0 4 4 4 0 Protein of unknown function (DUF4064) Glyco_hydro_61 PF03443.14 ORY12047.1 - 3.2e-55 187.3 0.0 4.7e-55 186.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.18 ORY12047.1 - 2.3e-12 46.7 8.4 2.3e-12 46.7 8.4 1.8 2 0 0 2 2 2 1 Fungal cellulose binding domain CBP_BcsO PF17037.5 ORY12047.1 - 0.92 9.6 4.1 1.9 8.6 4.1 1.4 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsO Mpv17_PMP22 PF04117.12 ORY12048.1 - 3.4e-17 62.4 0.6 6.5e-17 61.5 0.6 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family DUF3576 PF12100.8 ORY12048.1 - 0.12 12.5 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3576) Amidase PF01425.21 ORY12049.1 - 1.6e-67 228.4 3.8 2.9e-49 168.2 0.0 2.1 2 0 0 2 2 2 2 Amidase Vps51 PF08700.11 ORY12050.1 - 8.5e-32 109.1 0.1 3.1e-31 107.3 0.0 2.0 1 1 0 1 1 1 1 Vps51/Vps67 Dor1 PF04124.12 ORY12050.1 - 0.00087 18.1 0.2 0.0013 17.5 0.2 1.3 1 1 0 1 1 1 1 Dor1-like family COG5 PF10392.9 ORY12050.1 - 0.0011 19.2 0.4 0.0022 18.2 0.1 1.7 2 0 0 2 2 2 1 Golgi transport complex subunit 5 DUF1217 PF06748.12 ORY12050.1 - 0.043 13.8 0.2 7.4 6.6 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1217) RMI1_N PF08585.12 ORY12051.1 - 4e-58 196.7 0.0 4.7e-58 196.5 0.0 1.0 1 0 0 1 1 1 1 RecQ mediated genome instability protein Sec1 PF00995.23 ORY12052.1 - 0.35 10.0 1.2 1.4 8.0 0.5 2.1 1 1 0 1 1 1 0 Sec1 family Peptidase_C14 PF00656.22 ORY12053.1 - 7.2e-11 42.5 0.0 1.2e-10 41.7 0.0 1.3 1 0 0 1 1 1 1 Caspase domain Peptidase_C13 PF01650.18 ORY12053.1 - 0.024 14.1 0.0 0.08 12.5 0.0 1.8 1 0 0 1 1 1 0 Peptidase C13 family CHAT PF12770.7 ORY12054.1 - 1.6e-31 109.8 0.0 2.6e-31 109.1 0.0 1.3 1 0 0 1 1 1 1 CHAT domain Fis1_TPR_N PF14852.6 ORY12054.1 - 0.078 12.7 0.1 0.26 11.0 0.1 2.0 1 0 0 1 1 1 0 Fis1 N-terminal tetratricopeptide repeat Fungal_trans PF04082.18 ORY12068.1 - 5.3e-12 45.3 0.0 2.7e-11 43.0 0.0 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY12068.1 - 2e-08 34.2 8.3 4.4e-08 33.1 8.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-PHD-like PF15446.6 ORY12068.1 - 0.68 9.5 7.1 0.34 10.5 4.3 1.8 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain Sugar_tr PF00083.24 ORY12069.1 - 9.1e-74 248.9 26.9 1.1e-73 248.6 26.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY12069.1 - 3.3e-25 88.8 68.1 2.6e-23 82.5 35.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily p450 PF00067.22 ORY12071.1 - 6.8e-50 170.1 0.0 1.1e-49 169.5 0.0 1.2 1 1 0 1 1 1 1 Cytochrome P450 Apt1 PF10351.9 ORY12074.1 - 0.19 10.5 6.0 0.22 10.3 6.0 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Plasmodium_Vir PF05795.11 ORY12074.1 - 0.5 9.7 8.6 0.73 9.2 8.6 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Ndc1_Nup PF09531.10 ORY12074.1 - 0.71 8.5 11.9 0.99 8.0 11.9 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Presenilin PF01080.17 ORY12074.1 - 1.8 7.2 8.3 2.7 6.7 8.3 1.2 1 0 0 1 1 1 0 Presenilin QWRF PF04484.12 ORY12074.1 - 2 8.1 10.9 2.6 7.7 10.9 1.3 1 0 0 1 1 1 0 QWRF family His_Phos_1 PF00300.22 ORY12075.1 - 1.1e-13 51.3 0.0 2.2e-13 50.3 0.0 1.5 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Proteasome PF00227.26 ORY12076.1 - 1.9e-46 158.0 0.1 6.5e-31 107.3 0.0 2.3 1 1 1 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.9 ORY12076.1 - 5.6e-12 45.1 1.0 6.2e-12 45.0 0.0 1.6 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Methyltransf_32 PF13679.6 ORY12077.1 - 0.52 10.3 2.6 1 9.3 0.1 2.2 2 0 0 2 2 2 0 Methyltransferase domain Mitoc_mL59 PF18126.1 ORY12078.1 - 5.8e-41 139.8 1.8 9.1e-41 139.2 1.8 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein mL59 INO80_Ies4 PF08193.11 ORY12078.1 - 0.00057 20.0 1.5 0.00087 19.4 1.5 1.3 1 0 0 1 1 1 1 INO80 complex subunit Ies4 Proteasome PF00227.26 ORY12079.1 - 5e-40 137.0 0.0 6e-40 136.8 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit DEAD PF00270.29 ORY12080.1 - 7.5e-45 152.8 0.0 2.7e-44 151.0 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY12080.1 - 6.3e-30 103.8 0.0 1.4e-28 99.4 0.1 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY12080.1 - 0.00089 19.3 0.0 0.002 18.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF3334 PF11813.8 ORY12080.1 - 0.18 11.5 0.0 0.39 10.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3334) zf-rbx1 PF12678.7 ORY12081.1 - 4.5e-07 30.1 7.8 1.1e-06 28.8 7.8 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 ORY12081.1 - 7.9e-07 29.3 11.4 1.9e-05 24.9 11.4 2.4 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 ORY12081.1 - 3.7e-06 26.7 7.6 2e-05 24.3 7.6 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 ORY12081.1 - 6.9e-06 26.1 3.2 6.9e-06 26.1 3.2 2.2 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 ORY12081.1 - 1.2e-05 25.3 5.3 3.5e-05 23.7 5.3 1.9 1 1 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 ORY12081.1 - 3.1e-05 24.0 4.8 0.00011 22.2 4.7 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 ORY12081.1 - 0.00021 21.1 7.4 0.00048 19.9 2.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 ORY12081.1 - 0.00025 20.8 1.7 0.00025 20.8 1.7 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Pellino PF04710.14 ORY12081.1 - 0.00084 18.1 0.1 0.0015 17.3 0.1 1.3 1 0 0 1 1 1 1 Pellino zf-RING_5 PF14634.6 ORY12081.1 - 0.0016 18.4 7.8 0.0041 17.0 7.8 1.7 1 1 0 1 1 1 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 ORY12081.1 - 0.012 15.3 1.4 0.012 15.3 1.4 1.7 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING_6 PF14835.6 ORY12081.1 - 0.013 15.4 1.1 0.023 14.6 0.6 1.6 1 1 0 1 1 1 0 zf-RING of BARD1-type protein zf-Nse PF11789.8 ORY12081.1 - 0.018 14.9 1.5 0.037 13.8 1.5 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.6 ORY12081.1 - 0.04 13.8 8.7 0.22 11.4 8.7 2.1 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 Rtf2 PF04641.12 ORY12081.1 - 0.14 11.5 0.3 0.39 10.1 0.0 1.7 1 1 1 2 2 2 0 Rtf2 RING-finger zf-RING_11 PF17123.5 ORY12081.1 - 0.43 10.4 0.1 0.43 10.4 0.1 2.4 2 0 0 2 2 2 0 RING-like zinc finger RINGv PF12906.7 ORY12081.1 - 5.5 7.2 6.6 0.79 9.9 1.7 2.1 2 0 0 2 2 2 0 RING-variant domain Fer2_3 PF13085.6 ORY12083.1 - 3.1e-32 110.8 0.0 4.9e-32 110.2 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 ORY12083.1 - 1.1e-08 35.5 6.8 1.1e-08 35.5 6.8 2.0 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 ORY12083.1 - 1.6e-07 31.6 8.1 1.6e-07 31.6 8.1 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 ORY12083.1 - 1e-06 28.7 3.5 1e-06 28.7 3.5 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 ORY12083.1 - 0.0028 18.2 4.5 0.0028 18.2 4.5 2.4 2 2 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.27 ORY12083.1 - 0.012 15.5 0.4 0.012 15.5 0.4 2.2 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain SF3a60_bindingd PF12108.8 ORY12083.1 - 0.081 12.8 1.1 0.23 11.4 0.1 2.0 2 0 0 2 2 2 0 Splicing factor SF3a60 binding domain DUF1993 PF09351.10 ORY12083.1 - 0.15 12.2 0.0 0.24 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1993) Fer4_18 PF13746.6 ORY12083.1 - 0.99 9.6 6.1 0.87 9.8 0.1 2.7 3 0 0 3 3 3 0 4Fe-4S dicluster domain HAD PF12710.7 ORY12084.1 - 1.9e-05 25.1 0.0 0.0005 20.5 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF1788 PF08747.11 ORY12084.1 - 0.094 12.7 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1788) EXS PF03124.14 ORY12086.1 - 1.7e-112 376.0 5.4 1.9e-112 375.8 5.4 1.0 1 0 0 1 1 1 1 EXS family IBR PF01485.21 ORY12087.1 - 0.18 12.1 3.9 0.45 10.8 3.6 1.9 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain MFS_1 PF07690.16 ORY12088.1 - 4.1e-38 131.2 41.0 3.3e-37 128.2 31.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY12088.1 - 9.9e-10 37.9 3.2 9.9e-10 37.9 3.2 2.6 3 0 0 3 3 3 1 Sugar (and other) transporter Herpes_UL49_5 PF05702.11 ORY12088.1 - 0.043 13.9 4.2 0.049 13.7 2.0 2.1 2 0 0 2 2 2 0 Herpesvirus UL49.5 envelope/tegument protein DUF1129 PF06570.11 ORY12088.1 - 0.099 12.1 2.9 0.83 9.1 0.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) DUF2721 PF11026.8 ORY12088.1 - 5.9 6.8 12.4 0.85 9.5 1.6 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF2721) HSA PF07529.13 ORY12089.1 - 3.4e-14 52.9 1.0 3.4e-14 52.9 1.0 4.4 4 0 0 4 4 4 1 HSA Myb_DNA-bind_6 PF13921.6 ORY12089.1 - 5.6e-13 48.9 0.3 5.6e-13 48.9 0.3 2.7 4 0 0 4 4 4 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 ORY12089.1 - 0.00064 19.9 0.8 0.0017 18.5 0.8 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain WD40 PF00400.32 ORY12090.1 - 7.9e-10 39.2 0.0 3.6 8.6 0.0 6.5 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY12090.1 - 0.00014 22.1 0.0 5.4 7.4 0.0 4.5 5 1 1 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain AA_permease PF00324.21 ORY12091.1 - 1.7e-57 195.1 30.7 2.3e-57 194.6 30.7 1.2 1 0 0 1 1 1 1 Amino acid permease SLC12 PF03522.15 ORY12091.1 - 3.3e-24 85.7 6.9 6e-10 38.7 0.0 3.6 4 0 0 4 4 4 3 Solute carrier family 12 AA_permease_2 PF13520.6 ORY12091.1 - 1.8e-21 76.5 37.0 2.8e-21 75.9 37.0 1.2 1 0 0 1 1 1 1 Amino acid permease Peptidase_C33 PF05412.12 ORY12091.1 - 0.05 13.6 0.1 0.81 9.7 0.1 2.5 2 0 0 2 2 2 0 Equine arterivirus Nsp2-type cysteine proteinase Aa_trans PF01490.18 ORY12092.1 - 5.2e-87 292.2 33.6 6.4e-87 291.9 33.6 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein N-SET PF11764.8 ORY12094.1 - 9.4e-56 188.6 3.3 9.4e-56 188.6 3.3 3.1 3 0 0 3 3 3 2 COMPASS (Complex proteins associated with Set1p) component N SET_assoc PF11767.8 ORY12094.1 - 5e-27 93.3 0.3 1.4e-26 91.9 0.3 1.8 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated SET PF00856.28 ORY12094.1 - 7.6e-22 78.5 0.2 7.6e-22 78.5 0.2 3.1 3 1 0 3 3 3 1 SET domain RRM_1 PF00076.22 ORY12094.1 - 0.0047 16.7 0.0 0.014 15.2 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OTT_1508_deam PF14441.6 ORY12098.1 - 5.1e-16 58.4 2.1 9.5e-16 57.6 2.1 1.5 1 0 0 1 1 1 1 OTT_1508-like deaminase Pex2_Pex12 PF04757.14 ORY12099.1 - 8.2e-44 149.9 2.5 1e-43 149.5 2.5 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.6 ORY12099.1 - 4.1e-11 42.5 9.8 7e-11 41.8 9.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORY12099.1 - 6.2e-11 42.5 10.3 1e-10 41.7 10.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 ORY12099.1 - 5.2e-10 39.0 8.4 9e-10 38.3 8.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 ORY12099.1 - 1.2e-09 37.9 9.4 1.8e-09 37.3 9.4 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORY12099.1 - 1.9e-09 37.4 5.6 4.4e-09 36.2 5.6 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 ORY12099.1 - 1.3e-07 31.4 6.9 2.7e-07 30.5 6.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 ORY12099.1 - 4.3e-07 30.1 6.6 8.7e-07 29.1 6.6 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 ORY12099.1 - 1.1e-06 28.3 11.3 1.9e-06 27.6 11.3 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 ORY12099.1 - 6.4e-06 26.2 8.7 1.2e-05 25.3 8.7 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 ORY12099.1 - 0.0036 17.1 5.1 0.007 16.2 5.1 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_10 PF16685.5 ORY12099.1 - 0.066 13.3 9.5 0.14 12.3 9.5 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-ANAPC11 PF12861.7 ORY12099.1 - 0.075 13.1 4.1 0.15 12.2 4.1 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger U-box PF04564.15 ORY12099.1 - 0.076 13.2 0.0 0.26 11.5 0.0 1.9 2 0 0 2 2 2 0 U-box domain zf-RING_11 PF17123.5 ORY12099.1 - 0.091 12.5 3.9 0.23 11.2 3.9 1.7 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_4 PF14570.6 ORY12099.1 - 1.1 9.1 11.1 2.3 8.1 11.1 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF1455 PF07306.11 ORY12099.1 - 1.3 9.0 3.9 0.62 10.0 0.1 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1455) AF-4 PF05110.13 ORY12101.1 - 0.12 10.5 11.8 0.11 10.5 11.8 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Sporozoite_P67 PF05642.11 ORY12101.1 - 0.52 8.3 8.6 0.55 8.2 8.6 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RAP1 PF07218.11 ORY12101.1 - 1.9 6.7 12.9 2.1 6.5 12.9 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) CCDC24 PF15669.5 ORY12101.1 - 2.2 8.1 5.5 3.8 7.3 5.5 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family MAP70 PF07058.11 ORY12101.1 - 2.7 6.6 5.4 3 6.5 5.4 1.1 1 0 0 1 1 1 0 Microtubule-associated protein 70 Macoilin PF09726.9 ORY12101.1 - 3.1 6.2 8.0 3.1 6.2 8.0 1.1 1 0 0 1 1 1 0 Macoilin family RSRP PF17069.5 ORY12101.1 - 9.3 5.7 31.7 13 5.2 31.7 1.2 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 Glyco_hydro_47 PF01532.20 ORY12102.1 - 8e-165 549.2 0.0 9.3e-165 548.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 SP_C-Propep PF08999.10 ORY12103.1 - 0.027 14.3 0.1 0.067 13.0 0.1 1.6 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide Fungal_lectin PF07938.12 ORY12103.1 - 0.034 13.5 0.1 0.47 9.8 0.0 2.2 2 0 0 2 2 2 0 Fungal fucose-specific lectin MutS_V PF00488.21 ORY12104.1 - 2.8e-71 239.4 0.3 5.8e-71 238.4 0.0 1.7 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.18 ORY12104.1 - 1.5e-34 119.9 1.6 4.1e-34 118.5 1.6 1.8 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 ORY12104.1 - 6e-29 100.6 0.1 1.5e-28 99.3 0.1 1.7 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 ORY12104.1 - 1.2e-08 35.4 0.0 4e-08 33.6 0.0 2.0 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 ORY12104.1 - 5.8e-06 26.6 0.4 2.1e-05 24.8 0.4 2.0 1 0 0 1 1 1 1 MutS family domain IV DUF4911 PF16256.5 ORY12104.1 - 0.052 13.5 0.0 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4911) VWA_2 PF13519.6 ORY12105.1 - 4.1e-06 27.4 0.0 9.7e-06 26.2 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 ORY12105.1 - 4.5e-05 23.8 0.1 9.1e-05 22.8 0.1 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain AAA_16 PF13191.6 ORY12107.1 - 1.4e-11 45.1 1.6 3.1e-10 40.7 0.5 3.0 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 ORY12107.1 - 3.1e-11 43.7 0.0 1e-09 38.7 0.0 2.7 3 0 0 3 3 2 1 AAA domain AAA PF00004.29 ORY12107.1 - 3.1e-10 40.6 0.0 2.5e-09 37.6 0.0 2.4 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Cdc6_C PF09079.11 ORY12107.1 - 1e-09 38.3 0.2 8.2e-09 35.3 0.2 2.3 1 1 0 1 1 1 1 CDC6, C terminal winged helix domain AAA_lid_10 PF17872.1 ORY12107.1 - 9.1e-07 28.9 0.0 1.9e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 AAA lid domain AAA_19 PF13245.6 ORY12107.1 - 3.9e-05 24.0 0.1 0.00016 22.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 ORY12107.1 - 0.00078 19.4 0.1 0.0026 17.7 0.1 1.9 1 1 1 2 2 2 1 NTPase AAA_5 PF07728.14 ORY12107.1 - 0.0008 19.4 0.0 0.038 14.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) TniB PF05621.11 ORY12107.1 - 0.0023 17.3 0.0 0.008 15.6 0.0 1.9 2 0 0 2 2 2 1 Bacterial TniB protein AAA_11 PF13086.6 ORY12107.1 - 0.0041 17.0 0.0 0.009 15.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 ORY12107.1 - 0.0044 17.4 0.0 0.012 16.0 0.0 1.8 2 0 0 2 2 1 1 RNA helicase NACHT PF05729.12 ORY12107.1 - 0.005 16.8 0.0 0.012 15.6 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_7 PF12775.7 ORY12107.1 - 0.029 13.9 0.0 0.055 13.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Roc PF08477.13 ORY12107.1 - 0.03 14.5 0.0 0.057 13.6 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase ATPase_2 PF01637.18 ORY12107.1 - 0.03 14.2 0.2 0.16 11.9 0.2 2.1 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea PIF1 PF05970.14 ORY12107.1 - 0.035 13.3 0.0 0.06 12.5 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase AAA_30 PF13604.6 ORY12107.1 - 0.053 13.2 0.0 0.3 10.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 ORY12107.1 - 0.08 12.0 0.0 0.15 11.1 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_18 PF13238.6 ORY12107.1 - 0.14 12.7 0.0 0.27 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain RFX_DNA_binding PF02257.15 ORY12107.1 - 0.16 12.6 0.0 0.95 10.1 0.0 2.1 2 0 0 2 2 2 0 RFX DNA-binding domain NB-ARC PF00931.22 ORY12107.1 - 0.17 11.0 0.0 0.31 10.2 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain TIP49 PF06068.13 ORY12107.1 - 0.2 10.8 0.0 0.34 10.1 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AsnC_trans_reg PF01037.21 ORY12108.1 - 0.0012 18.8 0.0 0.0023 17.9 0.0 1.4 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain cobW PF02492.19 ORY12111.1 - 1.1e-42 145.7 0.0 1.6e-42 145.1 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.14 ORY12111.1 - 0.00023 21.1 0.0 0.00048 20.0 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.6 ORY12111.1 - 0.0025 18.1 0.0 0.024 14.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain CobW_C PF07683.14 ORY12111.1 - 0.036 14.0 0.0 0.41 10.6 0.0 2.4 1 1 0 1 1 1 0 Cobalamin synthesis protein cobW C-terminal domain AAA_29 PF13555.6 ORY12111.1 - 0.04 13.7 0.7 0.59 9.9 0.3 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain Viral_helicase1 PF01443.18 ORY12111.1 - 0.042 13.6 0.0 0.065 13.0 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RsgA_GTPase PF03193.16 ORY12111.1 - 0.053 13.4 0.1 14 5.5 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase AAA_18 PF13238.6 ORY12111.1 - 0.092 13.3 0.1 0.17 12.5 0.1 1.5 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 ORY12111.1 - 0.15 12.0 0.1 0.31 10.9 0.1 1.5 1 0 0 1 1 1 0 NTPase Pox_A32 PF04665.12 ORY12111.1 - 0.16 11.4 0.1 0.28 10.6 0.1 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_14 PF13173.6 ORY12111.1 - 0.17 11.9 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain MT0933_antitox PF14013.6 ORY12112.1 - 0.31 11.4 4.7 0.6 10.4 2.3 2.6 2 1 0 2 2 2 0 MT0933-like antitoxin protein APG5 PF04106.12 ORY12114.1 - 9.1e-61 205.3 0.0 1.1e-60 205.0 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg5 DUF4360 PF14273.6 ORY12115.1 - 2.6e-30 105.6 0.4 4.1e-30 105.0 0.4 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4360) Response_reg PF00072.24 ORY12116.1 - 1.2e-24 86.7 0.3 2.6e-24 85.5 0.3 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 ORY12116.1 - 4.3e-19 69.1 0.0 8.3e-19 68.1 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 ORY12116.1 - 3.6e-06 26.9 0.0 9.8e-06 25.5 0.0 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain E1-E2_ATPase PF00122.20 ORY12118.1 - 2.2e-52 177.2 3.3 1.1e-51 174.9 1.0 2.6 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 ORY12118.1 - 1.1e-44 152.3 5.9 1.1e-44 152.3 5.9 1.9 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 ORY12118.1 - 1.2e-23 84.5 1.5 1.1e-22 81.4 1.5 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 ORY12118.1 - 6.1e-21 74.3 0.0 1.3e-20 73.3 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 ORY12118.1 - 1.4e-19 69.5 0.1 4.1e-19 68.0 0.0 1.9 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 ORY12118.1 - 1.8e-09 37.7 1.1 2e-06 27.7 0.9 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 ORY12118.1 - 5e-07 30.3 0.0 1.3e-06 28.9 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Methyltransf_16 PF10294.9 ORY12121.1 - 7.8e-35 120.2 0.0 2.2e-19 69.9 0.0 2.2 2 0 0 2 2 2 2 Lysine methyltransferase Methyltransf_23 PF13489.6 ORY12121.1 - 0.00031 20.6 0.0 0.00049 20.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ORY12121.1 - 0.11 12.0 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain PCMT PF01135.19 ORY12121.1 - 0.17 11.6 0.0 0.27 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 ORY12121.1 - 0.18 12.5 0.3 1.1 10.1 0.0 2.3 3 0 0 3 3 3 0 Methyltransferase domain PAP1 PF08601.10 ORY12122.1 - 1.5 8.5 16.3 4.4 6.9 16.2 1.8 1 1 0 1 1 1 0 Transcription factor PAP1 WD40 PF00400.32 ORY12123.1 - 7.2e-21 74.1 6.5 6.8e-06 26.7 0.6 5.5 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY12123.1 - 2e-12 47.2 0.1 0.15 12.4 0.0 5.7 3 1 3 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain UAF_Rrn10 PF05234.11 ORY12124.1 - 0.00053 20.2 0.0 0.00058 20.1 0.0 1.2 1 0 0 1 1 1 1 UAF complex subunit Rrn10 Imm1 PF14430.6 ORY12124.1 - 0.013 16.2 0.0 0.017 15.8 0.0 1.2 1 0 0 1 1 1 0 Immunity protein Imm1 Mnd1 PF03962.15 ORY12125.1 - 1.7e-24 85.9 0.0 3.4e-24 84.9 0.0 1.5 1 0 0 1 1 1 1 Mnd1 HTH domain DUF4407 PF14362.6 ORY12125.1 - 0.011 15.1 2.8 0.014 14.8 2.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) LZ3wCH PF18517.1 ORY12125.1 - 0.017 15.2 1.0 0.017 15.2 1.0 2.3 2 1 0 2 2 2 0 Leucine zipper with capping helix domain ADIP PF11559.8 ORY12125.1 - 0.16 12.0 7.7 0.31 11.1 6.9 1.8 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding DivIC PF04977.15 ORY12125.1 - 0.21 11.4 5.4 0.23 11.2 0.3 2.6 2 1 1 3 3 3 0 Septum formation initiator ZapB PF06005.12 ORY12125.1 - 0.24 11.9 8.8 1.1 9.7 2.3 2.4 2 0 0 2 2 2 0 Cell division protein ZapB CENP-H PF05837.12 ORY12125.1 - 1.7 9.1 7.9 2.2 8.7 6.1 2.0 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Cnn_1N PF07989.11 ORY12125.1 - 6.1 7.1 9.5 1.6 8.9 0.3 3.2 3 1 1 4 4 4 0 Centrosomin N-terminal motif 1 zf-C3HC4_3 PF13920.6 ORY12126.1 - 1.6e-06 27.9 10.1 1.6e-06 27.9 10.1 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Tudor-knot PF11717.8 ORY12126.1 - 0.094 12.6 0.5 0.21 11.5 0.5 1.5 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain DUF971 PF06155.12 ORY12126.1 - 0.098 13.3 0.5 1.9 9.2 0.0 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF971) Velvet PF11754.8 ORY12128.1 - 1.6e-89 300.2 0.0 2e-89 299.8 0.0 1.1 1 0 0 1 1 1 1 Velvet factor YTH PF04146.15 ORY12129.1 - 3.7e-63 212.4 0.0 5.3e-63 211.9 0.0 1.2 1 0 0 1 1 1 1 YT521-B-like domain RRM_1 PF00076.22 ORY12129.1 - 9.3e-08 31.8 0.0 2.6e-07 30.3 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Hydrolase_4 PF12146.8 ORY12131.1 - 7.5e-17 61.4 0.0 3.5e-12 46.1 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ORY12131.1 - 2e-11 44.0 0.0 1.3e-09 38.1 0.0 2.1 1 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORY12131.1 - 2.2e-06 28.4 0.0 3.4e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.12 ORY12131.1 - 2.5e-06 26.4 0.1 0.0066 15.2 0.1 2.8 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) FSH1 PF03959.13 ORY12131.1 - 0.0002 21.1 0.0 0.00068 19.4 0.0 1.8 2 0 0 2 2 2 1 Serine hydrolase (FSH1) BAAT_C PF08840.11 ORY12131.1 - 0.00081 19.4 0.0 0.027 14.4 0.0 2.2 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.21 ORY12131.1 - 0.0011 18.5 0.0 0.01 15.3 0.0 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family DUF818 PF05677.12 ORY12131.1 - 0.0012 17.9 0.0 0.0016 17.5 0.0 1.1 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Abhydrolase_3 PF07859.13 ORY12131.1 - 0.0019 18.1 0.0 0.0029 17.5 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 ORY12131.1 - 0.024 14.4 0.2 1.3 8.8 0.1 2.4 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase DLH PF01738.18 ORY12131.1 - 0.025 14.1 0.0 1.1 8.7 0.0 2.3 2 0 0 2 2 2 0 Dienelactone hydrolase family Thioesterase PF00975.20 ORY12131.1 - 0.03 14.4 0.0 0.044 13.9 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain Esterase PF00756.20 ORY12131.1 - 0.15 11.7 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Proteasome PF00227.26 ORY12132.1 - 4.2e-47 160.1 0.2 4.8e-47 159.9 0.2 1.0 1 0 0 1 1 1 1 Proteasome subunit Cyclin PF08613.11 ORY12133.1 - 3.3e-40 138.1 6.7 4.8e-24 85.5 0.5 3.1 3 0 0 3 3 3 2 Cyclin 2OG-FeII_Oxy_3 PF13640.6 ORY12134.1 - 4.7e-13 49.8 0.1 8.1e-13 49.1 0.1 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Spherulin4 PF12138.8 ORY12135.1 - 2.2e-61 207.6 1.7 2.5e-61 207.4 1.7 1.0 1 0 0 1 1 1 1 Spherulation-specific family 4 RHH_3 PF12651.7 ORY12135.1 - 0.18 11.8 0.0 0.36 10.8 0.0 1.5 1 0 0 1 1 1 0 Ribbon-helix-helix domain SNF2_N PF00176.23 ORY12136.1 - 1.3e-14 53.7 0.0 1.4e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Cnn_1N PF07989.11 ORY12137.1 - 0.0035 17.5 2.2 0.011 15.8 2.2 1.8 1 0 0 1 1 1 1 Centrosomin N-terminal motif 1 TMF_DNA_bd PF12329.8 ORY12137.1 - 1.2 9.2 8.9 0.16 12.0 2.6 2.6 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding PI3_PI4_kinase PF00454.27 ORY12140.1 - 3.5e-41 141.7 0.0 6.1e-39 134.3 0.0 2.3 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 ORY12140.1 - 2.4e-23 82.5 0.1 6.5e-23 81.1 0.1 1.7 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Cnd2 PF05786.14 ORY12141.1 - 5.3e-301 1000.9 8.9 6e-301 1000.7 8.9 1.0 1 0 0 1 1 1 1 Condensin complex subunit 2 CNDH2_N PF06278.11 ORY12141.1 - 0.02 15.1 0.7 0.043 14.0 0.0 2.0 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal DASH_Spc19 PF08287.11 ORY12141.1 - 3.1 7.7 8.5 0.35 10.8 2.5 2.3 2 0 0 2 2 2 0 Spc19 Na_Ca_ex PF01699.24 ORY12142.1 - 9.1e-54 181.5 35.7 4.4e-29 101.4 19.2 2.7 2 1 1 3 3 3 2 Sodium/calcium exchanger protein CAP PF00188.26 ORY12144.1 - 5.6e-16 59.5 1.5 2.7e-15 57.3 1.5 2.0 1 1 0 1 1 1 1 Cysteine-rich secretory protein family DUF4298 PF14131.6 ORY12145.1 - 0.41 10.6 3.3 0.37 10.8 1.7 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4298) Kinesin PF00225.23 ORY12146.1 - 8.7e-94 314.2 0.0 8.7e-94 314.2 0.0 2.1 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 ORY12146.1 - 6.6e-23 81.3 0.0 1.1e-21 77.4 0.0 2.3 2 0 0 2 2 2 1 Microtubule binding PKcGMP_CC PF16808.5 ORY12146.1 - 0.11 12.4 0.1 0.11 12.4 0.1 4.2 4 0 0 4 4 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF5401 PF17380.2 ORY12146.1 - 0.35 8.9 12.5 0.56 8.2 12.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5401) DUF4407 PF14362.6 ORY12146.1 - 0.56 9.5 13.4 1.8 7.9 1.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF2407_C PF13373.6 ORY12146.1 - 0.72 10.0 6.9 0.63 10.2 4.8 2.0 2 0 0 2 2 2 0 DUF2407 C-terminal domain TFB6 PF17110.5 ORY12146.1 - 2.6 7.8 6.7 9 6.0 6.7 1.9 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Vfa1 PF08432.10 ORY12146.1 - 3.3 8.0 14.9 0.069 13.5 5.3 2.8 3 0 0 3 3 3 0 AAA-ATPase Vps4-associated protein 1 GNAT_acetyltr_2 PF13718.6 ORY12146.1 - 3.5 7.0 6.7 61 2.9 6.0 2.3 2 0 0 2 2 2 0 GNAT acetyltransferase 2 Tho2 PF11262.8 ORY12146.1 - 8.2 5.5 10.4 16 4.6 10.4 1.3 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DUF4055 PF13264.6 ORY12146.1 - 8.3 6.6 7.5 15 5.7 0.6 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4055) MAS20 PF02064.15 ORY12146.1 - 8.7 6.5 9.3 23 5.1 9.3 1.7 1 0 0 1 1 1 0 MAS20 protein import receptor RIC3 PF15361.6 ORY12146.1 - 8.8 6.7 9.1 35 4.8 6.3 2.9 2 0 0 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 WD40 PF00400.32 ORY12149.1 - 5.9e-49 163.0 26.4 3.3e-05 24.5 0.0 12.8 12 1 0 12 12 12 9 WD domain, G-beta repeat Utp13 PF08625.11 ORY12149.1 - 3e-47 160.1 0.0 4.7e-47 159.5 0.0 1.3 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain ANAPC4_WD40 PF12894.7 ORY12149.1 - 5.8e-14 52.2 4.8 0.36 11.2 0.0 8.8 5 4 2 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 ORY12149.1 - 6.2e-05 21.9 0.6 3.5 6.2 0.0 5.5 4 2 2 6 6 6 2 Nup133 N terminal like Nup160 PF11715.8 ORY12149.1 - 0.00017 20.4 8.6 2.7 6.5 0.0 5.3 3 2 1 5 5 5 4 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 ORY12149.1 - 0.0017 17.4 2.3 1.9 7.4 0.0 4.9 6 1 1 7 7 7 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 ORY12149.1 - 0.068 12.5 0.0 24 4.1 0.0 3.7 4 1 0 4 4 4 0 WD40-like domain Cytochrom_D1 PF02239.16 ORY12149.1 - 0.082 11.4 0.1 0.27 9.7 0.0 1.8 2 0 0 2 2 2 0 Cytochrome D1 heme domain T3SS_needle_E PF08988.10 ORY12150.1 - 0.022 14.9 1.0 0.1 12.8 0.8 2.2 2 1 0 2 2 2 0 Type III secretion system, cytoplasmic E component of needle SesA PF17107.5 ORY12150.1 - 0.086 13.0 0.1 0.25 11.5 0.1 1.8 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Ecm29 PF13001.7 ORY12152.1 - 4.9e-162 540.1 0.0 8.2e-160 532.7 0.0 2.7 2 0 0 2 2 2 2 Proteasome stabiliser Vac14_Fab1_bd PF12755.7 ORY12152.1 - 2.6e-09 37.6 0.0 0.0007 20.1 0.1 6.1 5 2 2 7 7 7 2 Vacuolar 14 Fab1-binding region MMS19_C PF12460.8 ORY12152.1 - 9.3e-07 28.3 2.0 0.0064 15.7 0.6 4.1 3 1 0 3 3 3 2 RNAPII transcription regulator C-terminal HEAT PF02985.22 ORY12152.1 - 6e-06 26.1 7.6 1 9.8 0.1 7.9 10 0 0 10 10 10 1 HEAT repeat IFRD PF05004.13 ORY12152.1 - 7.7e-05 21.9 3.2 0.29 10.2 0.0 4.1 4 0 0 4 4 4 2 Interferon-related developmental regulator (IFRD) HEAT_2 PF13646.6 ORY12152.1 - 0.00016 22.0 2.1 6.6 7.2 0.0 6.3 6 1 1 7 7 7 2 HEAT repeats CLASP_N PF12348.8 ORY12152.1 - 0.0015 18.1 1.6 0.12 11.9 0.0 3.7 3 1 0 3 3 3 1 CLASP N terminal HEAT_EZ PF13513.6 ORY12152.1 - 0.015 15.8 14.1 7 7.3 0.1 7.7 8 1 1 9 9 9 0 HEAT-like repeat Adaptin_N PF01602.20 ORY12152.1 - 0.047 12.3 1.0 13 4.2 0.0 3.8 3 1 0 3 3 3 0 Adaptin N terminal region Thioredoxin_7 PF13899.6 ORY12153.1 - 3.9e-17 62.2 0.2 7.5e-17 61.3 0.2 1.5 1 0 0 1 1 1 1 Thioredoxin-like UBA_4 PF14555.6 ORY12153.1 - 1.3e-14 53.7 0.1 2.9e-14 52.6 0.1 1.6 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.20 ORY12153.1 - 6.5e-08 32.7 0.0 1.4e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 UBX domain Thioredox_DsbH PF03190.15 ORY12153.1 - 0.057 13.4 0.1 0.094 12.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF255 Thioredoxin_2 PF13098.6 ORY12153.1 - 0.15 12.5 0.0 0.35 11.3 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like domain MOSC PF03473.17 ORY12154.1 - 2e-35 121.7 0.0 3.6e-35 120.8 0.0 1.4 1 0 0 1 1 1 1 MOSC domain Aminotran_5 PF00266.19 ORY12154.1 - 1e-26 93.8 0.0 1.7e-26 93.1 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V MOSC_N PF03476.16 ORY12154.1 - 1.4e-23 83.0 0.0 2.8e-23 82.1 0.0 1.5 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain TPPII_N PF12583.8 ORY12155.1 - 4.2 7.9 9.7 7.4 7.2 9.7 1.3 1 0 0 1 1 1 0 Tripeptidyl peptidase II N terminal ATP_bind_2 PF03668.15 ORY12157.1 - 0.15 11.3 0.0 0.31 10.3 0.0 1.5 2 0 0 2 2 2 0 P-loop ATPase protein family Astro_capsid_p PF12226.8 ORY12157.1 - 0.31 10.2 3.4 0.38 9.9 3.4 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Acetyltransf_1 PF00583.25 ORY12158.1 - 3.2e-08 33.8 0.0 6.5e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ORY12158.1 - 1.8e-07 31.5 0.0 3.5e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ORY12158.1 - 2.2e-06 27.6 0.0 3.7e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain RRM_1 PF00076.22 ORY12159.1 - 0.025 14.4 0.3 6.1 6.7 0.0 3.2 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SHR3_chaperone PF08229.11 ORY12160.1 - 9.9e-75 249.6 0.0 1.1e-74 249.5 0.0 1.0 1 0 0 1 1 1 1 ER membrane protein SH3 YajC PF02699.15 ORY12160.1 - 0.14 12.1 0.2 0.73 9.8 0.1 2.2 3 0 0 3 3 3 0 Preprotein translocase subunit DUF2157 PF09925.9 ORY12160.1 - 0.29 10.9 3.0 0.62 9.8 0.1 2.2 2 1 0 2 2 2 0 Predicted membrane protein (DUF2157) MCM PF00493.23 ORY12161.1 - 9e-104 345.4 0.0 1.4e-103 344.9 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 ORY12161.1 - 3.5e-32 110.9 0.9 6.1e-32 110.1 0.9 1.3 1 0 0 1 1 1 1 MCM OB domain MCM_N PF14551.6 ORY12161.1 - 9e-19 68.0 0.1 2e-18 66.9 0.1 1.6 1 0 0 1 1 1 1 MCM N-terminal domain MCM_lid PF17855.1 ORY12161.1 - 5.9e-18 65.1 0.2 1.5e-17 63.8 0.2 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 ORY12161.1 - 2.6e-07 30.2 0.0 2.5e-05 23.7 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 ORY12161.1 - 8.1e-06 25.9 0.0 2.1e-05 24.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_lid_2 PF17863.1 ORY12161.1 - 0.0076 16.1 0.0 0.026 14.4 0.0 1.9 1 0 0 1 1 1 1 AAA lid domain AAA_3 PF07726.11 ORY12161.1 - 0.028 14.3 0.0 0.093 12.6 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase_C PF13335.6 ORY12161.1 - 0.051 14.2 0.1 0.2 12.3 0.1 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI C-terminal Sigma54_activat PF00158.26 ORY12161.1 - 0.15 11.8 0.0 0.83 9.3 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain PEX-1N PF09262.11 ORY12162.1 - 7e-30 103.3 1.7 7.6e-30 103.2 0.5 1.7 2 0 0 2 2 2 1 Peroxisome biogenesis factor 1, N-terminal PEX-2N PF09263.10 ORY12162.1 - 0.00034 20.9 0.2 0.82 10.0 0.0 3.2 3 0 0 3 3 3 2 Peroxisome biogenesis factor 1, N-terminal DnaJ PF00226.31 ORY12182.1 - 4.1e-14 52.5 0.2 8.3e-14 51.5 0.2 1.5 1 0 0 1 1 1 1 DnaJ domain Sugar_tr PF00083.24 ORY12184.1 - 4.3e-44 151.1 17.2 6.1e-44 150.6 17.2 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY12184.1 - 3e-13 49.4 32.8 3e-13 49.4 32.8 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF4360 PF14273.6 ORY12186.1 - 6.6e-64 215.1 0.8 7.8e-64 214.8 0.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) SLT PF01464.20 ORY12187.1 - 0.0035 17.0 0.2 0.021 14.5 0.2 2.1 1 1 0 1 1 1 1 Transglycosylase SLT domain SPASM PF13186.6 ORY12187.1 - 0.023 15.2 0.0 0.074 13.6 0.0 2.0 1 0 0 1 1 1 0 Iron-sulfur cluster-binding domain Glucosaminidase PF01832.20 ORY12187.1 - 0.042 14.3 0.4 7 7.2 0.0 3.2 2 1 2 4 4 4 0 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase Ion_trans PF00520.31 ORY12188.1 - 2.4 7.3 8.8 0.052 12.8 1.8 1.8 2 0 0 2 2 2 0 Ion transport protein Gate PF07670.14 ORY12188.1 - 7.8 6.8 9.4 1.6 9.0 1.6 2.8 2 1 0 2 2 2 0 Nucleoside recognition FAD_binding_4 PF01565.23 ORY12190.1 - 5e-19 68.4 1.3 9.5e-19 67.5 1.3 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 ORY12190.1 - 3.3e-10 39.9 0.1 8.4e-10 38.6 0.1 1.7 1 0 0 1 1 1 1 Berberine and berberine like RNA_ligase PF09414.10 ORY12191.1 - 0.082 13.2 0.1 0.12 12.7 0.1 1.3 1 0 0 1 1 1 0 RNA ligase Phage_holin_4_1 PF05105.12 ORY12191.1 - 0.13 12.4 0.1 19 5.4 0.0 2.2 2 0 0 2 2 2 0 Bacteriophage holin family He_PIG_assoc PF10632.9 ORY12191.1 - 0.13 12.0 0.1 1.4 8.7 0.0 2.3 2 0 0 2 2 2 0 He_PIG associated, NEW1 domain of bacterial glycohydrolase Defensin_2 PF01097.18 ORY12192.1 - 1.9e-06 27.7 11.7 1.9e-06 27.7 11.7 2.0 2 0 0 2 2 2 1 Arthropod defensin Defensin_propep PF00879.18 ORY12192.1 - 0.17 12.2 0.0 0.37 11.1 0.0 1.6 1 0 0 1 1 1 0 Defensin propeptide NAD_binding_10 PF13460.6 ORY12195.1 - 0.00036 20.5 0.0 0.00047 20.1 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 ORY12195.1 - 0.0012 17.9 0.0 0.0014 17.7 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 ORY12195.1 - 0.058 12.5 0.0 4 6.5 0.0 2.1 2 0 0 2 2 2 0 Male sterility protein RmlD_sub_bind PF04321.17 ORY12195.1 - 0.065 12.3 0.0 0.094 11.8 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain DapB_N PF01113.20 ORY12195.1 - 0.14 12.3 0.0 0.29 11.3 0.0 1.6 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Polysacc_synt_2 PF02719.15 ORY12195.1 - 0.16 11.1 0.0 0.22 10.7 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein GMC_oxred_N PF00732.19 ORY12196.1 - 6.5e-63 212.9 0.0 8.4e-63 212.5 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 ORY12196.1 - 5.2e-31 108.1 0.0 9.8e-31 107.2 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 ORY12196.1 - 4e-06 26.1 1.4 6e-06 25.5 0.2 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.24 ORY12196.1 - 0.00015 21.5 0.1 0.062 12.9 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ORY12196.1 - 0.003 17.8 0.0 0.0094 16.2 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 ORY12196.1 - 0.026 13.6 0.3 0.092 11.8 0.1 1.8 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.17 ORY12196.1 - 0.053 12.7 2.7 0.054 12.7 0.0 2.3 3 0 0 3 3 3 0 Thi4 family GDI PF00996.18 ORY12196.1 - 0.24 9.9 0.1 0.49 8.8 0.0 1.4 2 0 0 2 2 2 0 GDP dissociation inhibitor Glyco_hydro_10 PF00331.20 ORY12197.1 - 3e-90 302.6 0.1 3.4e-90 302.4 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 YL1_C PF08265.11 ORY12197.1 - 0.19 11.5 0.8 0.38 10.6 0.8 1.5 1 0 0 1 1 1 0 YL1 nuclear protein C-terminal domain Pyr_redox_2 PF07992.14 ORY12198.1 - 3.9e-12 46.0 0.0 8.9e-12 44.8 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 ORY12198.1 - 6.1e-12 44.7 0.0 5.7e-11 41.5 0.0 2.2 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 ORY12198.1 - 9.2e-09 35.4 0.3 3.1e-08 33.7 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 ORY12198.1 - 9.2e-07 29.0 0.0 4.4e-06 26.8 0.0 2.3 2 1 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.17 ORY12198.1 - 3.2e-06 26.6 0.2 1.3e-05 24.6 0.2 1.9 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 ORY12198.1 - 6.5e-06 25.9 0.1 0.00078 19.1 0.1 2.9 2 1 1 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 ORY12198.1 - 3.2e-05 23.4 1.0 0.012 14.8 0.8 3.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ORY12198.1 - 5.2e-05 22.1 0.5 0.00029 19.6 0.2 2.1 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.19 ORY12198.1 - 0.00014 21.2 0.2 0.00061 19.1 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain K_oxygenase PF13434.6 ORY12198.1 - 0.00023 20.4 0.1 0.0088 15.2 0.0 2.3 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_oxidored PF12831.7 ORY12198.1 - 0.00093 18.6 0.0 0.0016 17.9 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 ORY12198.1 - 0.002 18.6 0.0 1.5 9.4 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ORY12198.1 - 0.0067 15.5 0.2 0.011 14.9 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.24 ORY12198.1 - 0.0073 15.6 0.0 0.016 14.5 0.0 1.6 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Trp_halogenase PF04820.14 ORY12198.1 - 0.083 11.7 0.1 0.3 9.9 0.1 1.8 2 0 0 2 2 2 0 Tryptophan halogenase Shikimate_DH PF01488.20 ORY12198.1 - 0.16 12.0 0.3 0.51 10.4 0.1 2.0 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase GIDA PF01134.22 ORY12198.1 - 0.77 8.8 2.6 1.6 7.7 0.3 2.5 3 0 0 3 3 3 0 Glucose inhibited division protein A MFS_1 PF07690.16 ORY12200.1 - 3e-41 141.5 46.8 8.7e-41 140.0 45.1 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 ORY12200.1 - 2.1e-23 82.6 19.0 2.6e-23 82.3 19.0 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 ORY12200.1 - 3.7e-14 52.4 9.1 3.7e-14 52.4 9.1 3.1 2 1 1 3 3 3 1 Sugar (and other) transporter Neurensin PF14927.6 ORY12200.1 - 0.072 12.8 0.0 1.4 8.7 0.0 3.1 2 0 0 2 2 2 0 Neurensin DUF4064 PF13273.6 ORY12203.1 - 0.02 15.2 1.5 0.35 11.2 0.3 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF4064) BTB PF00651.31 ORY12204.1 - 5.7e-07 29.7 0.7 0.00079 19.6 0.0 2.3 2 0 0 2 2 2 2 BTB/POZ domain BAR PF03114.18 ORY12204.1 - 0.97 9.0 7.4 0.66 9.6 0.6 3.0 2 1 1 3 3 3 0 BAR domain Rtt106 PF08512.12 ORY12205.1 - 4.1e-27 94.4 0.0 7e-27 93.7 0.0 1.4 1 0 0 1 1 1 1 Histone chaperone Rttp106-like Cwf_Cwc_15 PF04889.12 ORY12205.1 - 10 5.8 15.0 16 5.2 15.0 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Glyco_transf_90 PF05686.12 ORY12206.1 - 5.7e-14 51.8 0.6 1.3e-08 34.2 0.0 3.9 3 1 0 3 3 3 3 Glycosyl transferase family 90 PRIMA1 PF16101.5 ORY12207.1 - 0.087 12.9 0.3 0.087 12.9 0.3 2.8 3 0 0 3 3 3 0 Proline-rich membrane anchor 1 MIP PF00230.20 ORY12208.1 - 4.4e-46 157.4 14.5 5.9e-46 157.0 14.5 1.1 1 0 0 1 1 1 1 Major intrinsic protein Ferric_reduct PF01794.19 ORY12210.1 - 9.4e-23 80.7 5.9 9.4e-23 80.7 5.9 2.3 3 0 0 3 3 3 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 ORY12210.1 - 2.5e-11 43.6 0.1 6.2e-11 42.4 0.1 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 ORY12210.1 - 1.5e-08 35.0 0.0 1.6e-06 28.3 0.0 2.3 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Sdh_cyt PF01127.22 ORY12210.1 - 0.018 15.1 3.3 0.018 15.1 3.3 2.3 3 0 0 3 3 3 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit NAD_binding_1 PF00175.21 ORY12210.1 - 0.079 13.6 0.0 0.19 12.4 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase NAD-binding domain p450 PF00067.22 ORY12211.1 - 4e-56 190.7 0.0 5.4e-56 190.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ring_hydroxyl_A PF00848.19 ORY12212.1 - 4e-24 85.8 1.1 1.2e-12 48.2 0.0 2.2 1 1 1 2 2 2 2 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.26 ORY12213.1 - 1.9e-15 56.6 0.0 3.5e-15 55.7 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Helo_like_N PF17111.5 ORY12214.1 - 8.8e-08 31.8 0.0 1.6e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins HET PF06985.11 ORY12215.1 - 2.8e-14 53.7 0.4 4.7e-14 53.0 0.4 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF640 PF04852.12 ORY12215.1 - 0.0031 17.7 0.0 0.0077 16.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF640) DUF3405 PF11885.8 ORY12217.1 - 2.9e-230 765.3 1.7 3.6e-230 765.0 1.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) MFS_1 PF07690.16 ORY12218.1 - 6.8e-05 21.9 2.7 7.4e-05 21.8 2.7 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily GrpE PF01025.19 ORY12219.1 - 0.011 15.4 1.3 1 9.0 0.1 2.3 2 0 0 2 2 2 0 GrpE Helo_like_N PF17111.5 ORY12219.1 - 0.033 13.6 0.4 0.1 11.9 0.3 2.0 1 1 0 1 1 1 0 Fungal N-terminal domain of STAND proteins SesA PF17107.5 ORY12219.1 - 0.048 13.9 0.2 0.31 11.3 0.1 2.3 1 1 1 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Glyco_hydro_92 PF07971.12 ORY12223.1 - 1.1e-143 479.6 0.0 1.3e-143 479.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 ORY12223.1 - 2.3e-56 191.4 0.1 3.4e-56 190.8 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain ABM PF03992.16 ORY12224.1 - 0.014 15.5 0.0 0.43 10.7 0.0 2.3 2 0 0 2 2 2 0 Antibiotic biosynthesis monooxygenase Zn_clus PF00172.18 ORY12225.1 - 2.4e-08 34.0 10.8 5.7e-08 32.8 10.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 ORY12225.1 - 8e-08 31.5 1.0 1.1e-07 31.0 1.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Y_phosphatase2 PF03162.13 ORY12227.1 - 1.6e-47 161.2 0.0 2.3e-47 160.6 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 ORY12227.1 - 3.1e-06 27.3 0.0 8.4e-06 25.9 0.0 1.7 2 0 0 2 2 2 1 Tyrosine phosphatase family DSPc PF00782.20 ORY12227.1 - 0.00025 20.9 0.0 0.00036 20.3 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 ORY12227.1 - 0.0085 15.7 0.1 0.011 15.3 0.1 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DUF3984 PF13136.6 ORY12228.1 - 1.9e-49 168.9 34.3 1.2e-40 140.0 16.0 3.3 2 1 1 3 3 3 2 Protein of unknown function (DUF3984) YL1 PF05764.13 ORY12228.1 - 0.0035 17.5 11.9 0.0067 16.6 11.9 1.5 1 0 0 1 1 1 1 YL1 nuclear protein RNA_polI_A34 PF08208.11 ORY12228.1 - 0.47 10.5 8.2 0.42 10.7 6.5 1.7 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 Glyco_transf_22 PF03901.17 ORY12229.1 - 1.6e-80 271.4 8.1 1.9e-80 271.2 8.1 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Pkinase PF00069.25 ORY12230.1 - 7.5e-52 176.3 0.3 2.8e-35 122.0 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORY12230.1 - 2e-23 83.0 0.1 2.7e-22 79.3 0.1 2.7 1 1 0 1 1 1 1 Protein tyrosine kinase Rhodanese PF00581.20 ORY12233.1 - 4.9e-10 39.9 0.0 7.9e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain Dioxygenase_C PF00775.21 ORY12234.1 - 6.9e-07 28.9 0.0 1.2e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Dioxygenase MFS_1 PF07690.16 ORY12235.1 - 1.2e-14 54.0 28.3 1.2e-14 54.0 28.3 3.7 2 2 1 3 3 3 2 Major Facilitator Superfamily Zip PF02535.22 ORY12235.1 - 0.018 14.3 0.0 1.6 7.9 0.0 3.1 3 0 0 3 3 3 0 ZIP Zinc transporter DUF1189 PF06691.11 ORY12235.1 - 1.7 8.1 5.9 0.66 9.5 2.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1189) HECT PF00632.25 ORY12237.1 - 5.5e-98 328.2 0.0 7.4e-98 327.8 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 ORY12237.1 - 2.5e-33 113.8 18.9 1.2e-11 44.5 1.9 4.0 4 0 0 4 4 4 3 WW domain C2 PF00168.30 ORY12237.1 - 1.2e-19 70.5 0.0 3.1e-19 69.2 0.0 1.7 1 0 0 1 1 1 1 C2 domain ABC1 PF03109.16 ORY12239.1 - 1e-33 116.0 0.0 1.8e-33 115.2 0.0 1.4 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.22 ORY12239.1 - 0.085 12.4 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 RIO1 family CRM1_C PF08767.11 ORY12240.1 - 2e-133 444.5 2.3 2e-133 444.5 2.3 3.1 3 0 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.12 ORY12240.1 - 4.8e-39 133.8 7.4 6.9e-39 133.3 2.3 3.6 2 1 1 3 3 3 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 ORY12240.1 - 7.7e-34 115.2 2.4 2.4e-33 113.5 1.9 2.2 2 0 0 2 2 2 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 ORY12240.1 - 2.9e-29 100.9 0.7 2.9e-29 100.9 0.7 2.9 3 0 0 3 3 3 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 ORY12240.1 - 3.5e-20 71.2 1.3 9.5e-20 69.8 1.3 1.8 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 ORY12240.1 - 3.8e-13 49.2 0.1 1.6e-12 47.2 0.1 2.2 1 0 0 1 1 1 1 Importin-beta N-terminal domain DUF3385 PF11865.8 ORY12240.1 - 0.039 13.9 7.0 0.24 11.3 0.0 4.8 5 1 0 6 6 6 0 Domain of unknown function (DUF3385) Vac14_Fab1_bd PF12755.7 ORY12240.1 - 0.17 12.5 0.6 5.9 7.6 0.0 3.5 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region Aa_trans PF01490.18 ORY12242.1 - 2e-17 63.0 25.3 2.4e-17 62.8 25.3 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein SAYSvFN PF10260.9 ORY12242.1 - 0.14 12.1 2.0 0.5 10.3 2.0 2.0 1 0 0 1 1 1 0 Uncharacterized conserved domain (SAYSvFN) AhpC-TSA PF00578.21 ORY12244.1 - 4.4e-25 88.0 0.0 8.3e-25 87.1 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 ORY12244.1 - 5.7e-15 55.3 0.0 1.1e-14 54.4 0.0 1.5 1 0 0 1 1 1 1 Redoxin Dabb PF07876.12 ORY12245.1 - 0.00021 21.8 0.0 0.00029 21.4 0.0 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain DUF1761 PF08570.10 ORY12246.1 - 6.3e-29 100.8 3.9 7.2e-29 100.6 3.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1761) Bac_export_2 PF01312.19 ORY12246.1 - 0.074 12.3 0.2 0.097 11.9 0.2 1.1 1 0 0 1 1 1 0 FlhB HrpN YscU SpaS Family HET PF06985.11 ORY12247.1 - 2.2e-24 86.4 0.1 3.8e-24 85.7 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SpoIIID PF12116.8 ORY12247.1 - 0.21 11.7 0.2 1.4 9.1 0.0 2.4 3 0 0 3 3 3 0 Stage III sporulation protein D Glutaredoxin PF00462.24 ORY12248.1 - 8.6e-16 57.9 0.0 1.4e-15 57.2 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin zf-C2H2_12 PF18658.1 ORY12249.1 - 0.14 11.7 0.2 0.8 9.3 0.1 2.1 2 0 0 2 2 2 0 Zinc-finger C2H2-type peroxidase PF00141.23 ORY12250.1 - 4.1e-48 164.1 0.0 6.5e-48 163.4 0.0 1.3 1 0 0 1 1 1 1 Peroxidase Spt4 PF06093.13 ORY12251.1 - 0.068 13.3 0.6 0.17 12.0 0.6 1.6 1 0 0 1 1 1 0 Spt4/RpoE2 zinc finger MFS_1 PF07690.16 ORY12252.1 - 4.1e-37 127.9 23.3 4.1e-37 127.9 23.3 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1772 PF08592.11 ORY12252.1 - 1.6 9.0 12.8 2.2 8.6 0.0 3.8 2 2 0 3 3 3 0 Domain of unknown function (DUF1772) PepSY_TM_like_2 PF16357.5 ORY12252.1 - 3.2 7.7 5.0 1.2 9.1 0.9 2.4 2 0 0 2 2 2 0 Putative PepSY_TM-like Peptidase_A8 PF01252.18 ORY12252.1 - 7.7 6.7 8.6 23 5.2 0.1 3.2 2 2 1 3 3 3 0 Signal peptidase (SPase) II DUF5315 PF17242.2 ORY12253.1 - 4.9e-23 80.7 2.1 1.3e-22 79.4 2.1 1.7 1 0 0 1 1 1 1 Disordered region of unknown function (DUF5315) ATP-synt_DE PF00401.20 ORY12253.1 - 0.019 15.2 1.6 0.019 15.2 1.6 2.0 2 0 0 2 2 2 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain UPF0524 PF15823.5 ORY12253.1 - 0.13 11.6 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 UPF0524 of C3orf70 Ribosom_S12_S23 PF00164.25 ORY12254.1 - 6.5e-51 170.8 0.7 8e-51 170.5 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Ima1_N PF09779.9 ORY12255.1 - 7.5e-32 111.0 5.6 2e-31 109.6 5.6 1.8 1 0 0 1 1 1 1 Ima1 N-terminal domain DZR PF12773.7 ORY12255.1 - 0.038 14.0 3.9 4 7.6 0.4 2.6 2 0 0 2 2 2 0 Double zinc ribbon zf-RRPl_C4 PF17026.5 ORY12255.1 - 0.73 10.0 6.4 2.8 8.1 6.4 2.1 1 1 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type Endonuclease_7 PF02945.15 ORY12255.1 - 1.6 8.7 9.6 12 5.9 2.3 3.8 3 1 0 3 3 3 0 Recombination endonuclease VII KOW PF00467.29 ORY12256.1 - 5.4e-06 26.2 0.3 1e-05 25.3 0.3 1.4 1 0 0 1 1 1 1 KOW motif Exonuc_VII_L PF02601.15 ORY12256.1 - 2.7 7.5 6.4 2 7.9 0.4 2.2 2 0 0 2 2 2 0 Exonuclease VII, large subunit Alg14 PF08660.11 ORY12257.1 - 5.6e-54 182.7 0.1 7.6e-37 126.9 0.0 2.4 2 1 0 2 2 2 2 Oligosaccharide biosynthesis protein Alg14 like Spt20 PF12090.8 ORY12257.1 - 0.085 12.5 3.5 0.11 12.0 3.5 1.3 1 0 0 1 1 1 0 Spt20 family DUF1180 PF06679.12 ORY12257.1 - 0.18 12.2 3.6 1.7 9.0 1.7 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1180) Neur_chan_memb PF02932.16 ORY12257.1 - 0.27 11.3 3.1 0.69 9.9 3.1 1.6 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region NACHT PF05729.12 ORY12258.1 - 3.7e-07 30.2 0.2 1.1e-06 28.7 0.0 1.9 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 ORY12258.1 - 4.5e-05 23.8 0.0 0.00012 22.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain Hemerythrin PF01814.23 ORY12258.1 - 3.8 8.1 8.0 11 6.6 0.7 3.4 3 0 0 3 3 3 0 Hemerythrin HHE cation binding domain NIF PF03031.18 ORY12259.1 - 4.6e-54 182.4 0.0 6.6e-54 181.9 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase IF-2B PF01008.17 ORY12260.1 - 4.1e-57 193.5 6.2 5e-55 186.7 6.2 2.5 1 1 0 1 1 1 1 Initiation factor 2 subunit family DUF2508 PF10704.9 ORY12260.1 - 0.077 13.2 0.1 0.2 11.8 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2508) adh_short_C2 PF13561.6 ORY12262.1 - 3e-37 128.4 0.0 4e-37 128.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY12262.1 - 2.5e-28 98.9 0.0 3.7e-28 98.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_deac_1 PF01522.21 ORY12262.1 - 7.9e-10 38.7 0.0 1.4e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 ORY12262.1 - 0.0013 18.4 0.0 0.0022 17.7 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) Epimerase PF01370.21 ORY12262.1 - 0.0018 17.8 0.0 0.0068 15.9 0.0 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family La_HTH_kDCL PF18177.1 ORY12262.1 - 0.023 15.0 0.0 3.5 8.0 0.1 2.7 2 0 0 2 2 2 0 La HTH in kinetoplastid DICER domain 3Beta_HSD PF01073.19 ORY12262.1 - 0.047 12.7 0.0 0.091 11.7 0.0 1.5 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF3674 PF12426.8 ORY12262.1 - 0.048 13.7 0.1 0.33 11.0 0.4 2.3 2 0 0 2 2 2 0 RNA dependent RNA polymerase NAD_binding_10 PF13460.6 ORY12262.1 - 0.079 12.9 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding NmrA PF05368.13 ORY12262.1 - 0.11 12.0 0.0 0.23 11.0 0.0 1.5 2 0 0 2 2 2 0 NmrA-like family DPBB_1 PF03330.18 ORY12263.1 - 0.0015 18.8 0.1 0.0082 16.4 0.1 2.1 1 1 0 1 1 1 1 Lytic transglycolase FlgN PF05130.12 ORY12266.1 - 0.013 16.0 3.7 0.013 16.0 3.7 1.5 2 0 0 2 2 2 0 FlgN protein Lyase_8_N PF08124.11 ORY12266.1 - 0.02 13.8 1.3 0.031 13.2 1.3 1.2 1 0 0 1 1 1 0 Polysaccharide lyase family 8, N terminal alpha-helical domain Rotamase PF00639.21 ORY12266.1 - 0.061 14.3 5.2 0.35 11.8 5.2 2.1 1 1 0 1 1 1 0 PPIC-type PPIASE domain Med9 PF07544.13 ORY12266.1 - 0.8 9.8 7.0 0.39 10.8 4.2 1.8 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 HDA2-3 PF11496.8 ORY12266.1 - 1.2 8.3 5.3 0.22 10.6 0.3 1.8 1 1 1 2 2 2 0 Class II histone deacetylase complex subunits 2 and 3 YebO PF13974.6 ORY12266.1 - 2.4 8.3 6.2 2.9 8.0 4.9 1.8 1 1 1 2 2 2 0 YebO-like protein Pkinase PF00069.25 ORY12267.1 - 1.6e-15 57.2 0.0 3.1e-14 53.0 0.0 2.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY12267.1 - 0.00013 21.4 0.0 0.057 12.7 0.0 2.4 2 1 0 2 2 2 2 Protein tyrosine kinase S36_mt PF10937.8 ORY12268.1 - 1.9e-42 145.5 0.4 2.2e-42 145.3 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S36, mitochondrial Med18 PF09637.10 ORY12269.1 - 2.7e-51 174.8 0.0 3e-51 174.7 0.0 1.0 1 0 0 1 1 1 1 Med18 protein PNK3P PF08645.11 ORY12270.1 - 5.4e-55 185.5 0.0 9.5e-54 181.5 0.0 2.1 2 0 0 2 2 2 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.6 ORY12270.1 - 8e-24 84.4 0.0 3.4e-21 75.9 0.0 2.4 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 ORY12270.1 - 0.065 12.5 0.0 0.68 9.2 0.0 2.2 1 1 1 2 2 2 0 Zeta toxin KTI12 PF08433.10 ORY12270.1 - 0.16 11.4 0.0 6.4 6.1 0.0 2.1 2 0 0 2 2 2 0 Chromatin associated protein KTI12 SKG6 PF08693.10 ORY12285.1 - 0.14 11.6 0.0 0.14 11.6 0.0 2.8 4 0 0 4 4 4 0 Transmembrane alpha-helix domain Zn_clus PF00172.18 ORY12287.1 - 1.4e-06 28.3 9.7 3e-06 27.2 9.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 ORY12287.1 - 6.9e-06 25.1 1.1 6.9e-06 25.1 1.1 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY12290.1 - 4.9e-08 33.0 6.4 7e-08 32.5 6.4 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SOG2 PF10428.9 ORY12290.1 - 1.3 8.1 10.4 0.56 9.4 8.4 1.3 1 1 0 1 1 1 0 RAM signalling pathway protein DUF2461 PF09365.10 ORY12291.1 - 1.6e-74 250.4 0.0 2.1e-74 250.0 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical protein (DUF2461) TYW3 PF02676.14 ORY12292.1 - 2.5e-67 226.3 0.0 3.2e-67 226.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase TYW3 Methyltransf_23 PF13489.6 ORY12293.1 - 2.3e-12 47.1 0.2 3.4e-12 46.5 0.2 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY12293.1 - 2.8e-08 34.3 0.0 6.3e-08 33.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY12293.1 - 2.5e-07 31.3 0.0 4.9e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY12293.1 - 3.1e-07 31.0 0.0 7.8e-07 29.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY12293.1 - 0.00016 21.5 0.0 0.00028 20.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORY12293.1 - 0.0017 17.7 0.0 0.0036 16.7 0.0 1.6 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family eIF-1a PF01176.19 ORY12295.1 - 3.6e-22 77.9 0.0 5.2e-22 77.4 0.0 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 ERCC4 PF02732.15 ORY12296.1 - 1e-19 71.3 0.0 1.9e-19 70.4 0.0 1.5 1 0 0 1 1 1 1 ERCC4 domain HHH_5 PF14520.6 ORY12296.1 - 0.0087 16.7 0.0 0.018 15.6 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain CBP4 PF07960.11 ORY12297.1 - 2.6e-30 104.9 1.2 2.9e-30 104.8 1.2 1.0 1 0 0 1 1 1 1 CBP4 DUF4574 PF15141.6 ORY12297.1 - 0.00059 19.7 2.5 0.00098 19.0 0.0 2.0 1 1 1 2 2 2 1 Ubiquinol-cytochrome-c reductase complex assembly factor 3 Topoisom_I_N PF02919.15 ORY12297.1 - 0.053 13.0 0.8 0.059 12.9 0.8 1.0 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, DNA binding fragment ERCC4 PF02732.15 ORY12297.1 - 0.061 13.5 0.2 0.07 13.3 0.2 1.2 1 0 0 1 1 1 0 ERCC4 domain APG6_N PF17675.1 ORY12297.1 - 0.4 11.2 12.2 0.66 10.5 12.2 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF2852 PF11014.8 ORY12297.1 - 0.79 9.9 8.2 0.24 11.5 1.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2852) Sel1 PF08238.12 ORY12298.1 - 1.7e-38 130.2 25.4 1.1e-07 32.3 0.1 7.7 7 0 0 7 7 7 7 Sel1 repeat TPR_6 PF13174.6 ORY12298.1 - 0.12 13.0 8.8 5.6 7.8 0.1 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY12298.1 - 0.28 11.4 5.5 0.46 10.7 0.2 3.2 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 ORY12298.1 - 3.8 8.1 9.5 16 6.1 0.6 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat GATase_6 PF13522.6 ORY12299.1 - 2.4e-13 50.5 0.0 5.1e-13 49.4 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 ORY12299.1 - 2.6e-11 43.5 0.0 5.2e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 ORY12299.1 - 3e-06 26.8 0.0 6.5e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain S-methyl_trans PF02574.16 ORY12299.1 - 0.084 12.7 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Homocysteine S-methyltransferase Glyco_hydro_76 PF03663.14 ORY12300.1 - 4.4e-153 510.1 19.5 5.1e-153 509.9 19.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Melibiase PF02065.18 ORY12300.1 - 0.035 13.1 0.1 0.052 12.5 0.1 1.1 1 0 0 1 1 1 0 Melibiase Glyco_hydro_88 PF07470.13 ORY12300.1 - 0.1 11.6 11.9 0.26 10.3 0.6 3.1 2 1 1 3 3 3 0 Glycosyl Hydrolase Family 88 DUF3526 PF12040.8 ORY12301.1 - 0.019 15.5 0.1 0.029 14.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3526) Synaptobrevin PF00957.21 ORY12302.1 - 1.8e-18 66.1 0.5 2e-18 66.0 0.5 1.0 1 0 0 1 1 1 1 Synaptobrevin Synaptobrevin PF00957.21 ORY12303.1 - 0.00067 19.4 7.0 0.0014 18.4 7.0 1.5 1 0 0 1 1 1 1 Synaptobrevin Chi-conotoxin PF16981.5 ORY12303.1 - 0.17 12.1 2.0 1.1 9.5 0.1 2.3 2 0 0 2 2 2 0 chi-Conotoxin or t superfamily NAT PF04768.13 ORY12304.1 - 1.1e-39 135.8 0.0 1.9e-39 135.1 0.0 1.4 1 0 0 1 1 1 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase Semialdhyde_dh PF01118.24 ORY12304.1 - 1.3e-32 112.8 0.0 4.6e-32 111.0 0.0 2.0 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.28 ORY12304.1 - 5.8e-29 101.4 0.0 1.3e-28 100.2 0.0 1.6 1 0 0 1 1 1 1 Amino acid kinase family Sacchrp_dh_NADP PF03435.18 ORY12304.1 - 0.0053 17.0 0.0 0.013 15.8 0.0 1.7 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain POTRA_3 PF17287.2 ORY12304.1 - 0.011 15.2 0.0 0.035 13.6 0.0 1.8 1 0 0 1 1 1 0 POTRA domain Biliv-reduc_cat PF09166.10 ORY12304.1 - 0.017 15.4 0.1 0.035 14.4 0.1 1.4 1 0 0 1 1 1 0 Biliverdin reductase, catalytic GFO_IDH_MocA PF01408.22 ORY12304.1 - 0.019 15.8 0.0 0.045 14.6 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold DapB_N PF01113.20 ORY12304.1 - 0.027 14.6 0.0 0.077 13.1 0.0 1.8 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus CorA PF01544.18 ORY12305.1 - 5.6e-10 39.0 0.7 8.5e-10 38.4 0.7 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DDE_Tnp_ISL3 PF01610.17 ORY12305.1 - 0.054 13.2 0.1 0.08 12.7 0.1 1.2 1 0 0 1 1 1 0 Transposase DUF2274 PF10038.9 ORY12305.1 - 0.13 12.7 0.9 0.84 10.1 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2274) GMC_oxred_N PF00732.19 ORY12306.1 - 0.044 13.2 0.2 0.056 12.8 0.2 1.1 1 0 0 1 1 1 0 GMC oxidoreductase UBA PF00627.31 ORY12307.1 - 0.00062 19.6 0.1 0.0013 18.6 0.1 1.6 1 0 0 1 1 1 1 UBA/TS-N domain PIP5K PF01504.18 ORY12308.1 - 1.1e-39 136.3 0.0 3e-38 131.6 0.0 2.1 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase ENT PF03735.14 ORY12308.1 - 0.0052 16.8 0.9 2 8.6 0.1 2.5 2 0 0 2 2 2 2 ENT domain SnoaL PF07366.12 ORY12309.1 - 0.0002 21.1 0.0 0.00038 20.3 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 ORY12309.1 - 0.019 15.6 0.0 0.051 14.2 0.0 1.7 1 0 0 1 1 1 0 SnoaL-like domain Thy1 PF02511.15 ORY12309.1 - 0.14 11.9 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 Thymidylate synthase complementing protein Cyclin PF08613.11 ORY12311.1 - 2.5e-06 28.0 0.8 7.3e-06 26.4 0.0 2.2 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 ORY12311.1 - 0.012 15.4 0.2 0.023 14.5 0.2 1.5 1 1 0 1 1 1 0 Cyclin, N-terminal domain YIF1 PF03878.15 ORY12312.1 - 3.1e-96 321.5 1.5 3.6e-96 321.3 1.5 1.0 1 0 0 1 1 1 1 YIF1 SRP-alpha_N PF04086.13 ORY12313.1 - 8.9e-76 255.6 0.0 1.1e-75 255.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.22 ORY12313.1 - 6.2e-48 163.0 0.0 1.1e-47 162.2 0.0 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.19 ORY12313.1 - 3.5e-08 33.6 0.0 1e-07 32.1 0.0 1.8 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain MeaB PF03308.16 ORY12313.1 - 5.8e-07 28.8 0.0 1.1e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 ORY12313.1 - 0.0042 16.8 0.0 0.0086 15.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 ORY12313.1 - 0.0057 16.0 0.0 0.026 13.8 0.0 2.0 1 1 0 1 1 1 1 Zeta toxin AAA_17 PF13207.6 ORY12313.1 - 0.009 16.4 0.2 0.036 14.5 0.1 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 ORY12313.1 - 0.034 14.5 0.0 0.086 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 ORY12313.1 - 0.049 13.8 0.2 0.13 12.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain CbiA PF01656.23 ORY12313.1 - 0.05 13.7 0.1 2.1 8.4 0.0 2.5 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain ABC_tran PF00005.27 ORY12313.1 - 0.072 13.6 0.0 0.14 12.7 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 ORY12313.1 - 0.1 12.3 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 ORY12313.1 - 0.1 12.7 0.1 0.42 10.7 0.1 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_31 PF13614.6 ORY12313.1 - 0.16 11.9 0.0 0.67 9.8 0.0 1.9 1 1 0 2 2 2 0 AAA domain Gly-zipper_Omp PF13488.6 ORY12314.1 - 0.00043 20.2 10.0 0.00082 19.3 10.0 1.3 1 0 0 1 1 1 1 Glycine zipper DUF3824 PF12868.7 ORY12314.1 - 0.006 17.3 4.0 0.006 17.3 4.0 6.4 2 1 4 6 6 6 1 Domain of unknwon function (DUF3824) DUF456 PF04306.13 ORY12314.1 - 0.036 14.4 1.8 0.058 13.7 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF456) DUF1269 PF06897.12 ORY12314.1 - 0.13 12.6 3.5 0.21 11.9 3.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) Bacteriocin_IIc PF10439.9 ORY12314.1 - 0.37 10.9 12.5 0.63 10.2 12.5 1.3 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Gly-zipper_YMGG PF13441.6 ORY12314.1 - 1 9.2 18.3 1.9 8.3 18.3 1.3 1 0 0 1 1 1 0 YMGG-like Gly-zipper Rick_17kDa_Anti PF05433.15 ORY12314.1 - 6.3 6.8 22.3 32 4.5 22.8 1.9 1 1 0 1 1 1 0 Glycine zipper 2TM domain UBM PF14377.6 ORY12315.1 - 0.04 13.4 0.0 0.12 11.9 0.0 1.8 1 0 0 1 1 1 0 Ubiquitin binding region DNA_methylase PF00145.17 ORY12316.1 - 4.7e-36 124.8 0.1 2e-25 89.8 0.0 2.8 2 1 1 3 3 3 2 C-5 cytosine-specific DNA methylase DUF1690 PF07956.11 ORY12317.1 - 4.5e-30 104.9 21.0 1.3e-29 103.4 21.0 1.6 1 1 0 1 1 1 1 Protein of Unknown function (DUF1690) Rootletin PF15035.6 ORY12317.1 - 0.0011 19.0 20.4 0.0022 18.1 20.5 1.4 1 1 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion Apolipoprotein PF01442.18 ORY12317.1 - 0.18 11.7 17.9 0.41 10.5 17.9 1.5 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain FapA PF03961.13 ORY12317.1 - 0.26 9.9 5.7 0.32 9.5 5.7 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A Exonuc_VII_L PF02601.15 ORY12317.1 - 0.58 9.7 10.3 0.7 9.4 10.3 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit COG2 PF06148.11 ORY12317.1 - 0.73 9.9 11.0 4.5 7.4 9.8 2.4 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4407 PF14362.6 ORY12317.1 - 1.2 8.5 12.9 1.6 8.0 12.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) zf-C2HE PF16278.5 ORY12317.1 - 3.1 8.3 8.1 2.6 8.6 0.8 2.6 2 1 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger DUF1525 PF07511.11 ORY12317.1 - 7.7 6.7 8.0 2.7 8.2 1.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1525) Goodbye PF17109.5 ORY12317.1 - 9.7 6.7 8.5 7.9 7.0 1.5 2.6 1 1 2 3 3 3 0 fungal STAND N-terminal Goodbye domain Acetyltransf_1 PF00583.25 ORY12318.1 - 2.6e-11 43.8 0.0 4.2e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family CBM_1 PF00734.18 ORY12318.1 - 3.3e-10 39.7 8.2 3.3e-10 39.7 8.2 1.9 2 0 0 2 2 2 1 Fungal cellulose binding domain Acetyltransf_10 PF13673.7 ORY12318.1 - 5.6e-07 29.5 0.0 9.3e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ORY12318.1 - 6.7e-06 26.4 0.0 1.3e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ORY12318.1 - 0.0011 18.9 0.0 0.0019 18.1 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 ORY12318.1 - 0.0064 17.2 0.0 0.01 16.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 ORY12318.1 - 0.0065 16.6 0.0 0.01 16.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain His_Phos_1 PF00300.22 ORY12319.1 - 1.1e-33 116.6 2.4 4.5e-17 62.4 0.3 2.7 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) zf-C2H2 PF00096.26 ORY12320.1 - 1.6e-09 37.7 25.5 0.13 12.8 0.1 6.2 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY12320.1 - 3.4e-08 33.7 28.4 0.39 11.7 1.1 6.5 6 0 0 6 6 6 5 C2H2-type zinc finger zf-met PF12874.7 ORY12320.1 - 3.8e-05 23.9 26.2 0.36 11.3 0.1 6.6 7 0 0 7 7 7 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 ORY12320.1 - 0.011 16.0 24.3 2.2 8.7 0.2 5.9 6 0 0 6 6 6 0 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 ORY12320.1 - 0.012 15.4 22.5 0.32 10.8 2.1 5.8 5 0 0 5 5 5 0 zinc-finger C2H2-type DNA_pol_A_exo1 PF01612.20 ORY12320.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 3'-5' exonuclease zf-3CxxC_2 PF17180.4 ORY12320.1 - 4.5 8.1 11.5 2.1 9.2 0.7 3.8 3 0 0 3 3 3 0 Zinc-binding domain zf-C2H2_aberr PF17017.5 ORY12320.1 - 4.7 7.3 10.1 9 6.4 0.1 3.9 3 1 0 4 4 4 0 Aberrant zinc-finger Abhydrolase_2 PF02230.16 ORY12321.1 - 1.1e-24 87.5 0.3 1e-17 64.7 0.1 2.1 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase FSH1 PF03959.13 ORY12321.1 - 0.0005 19.8 0.0 0.00079 19.1 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) DLH PF01738.18 ORY12321.1 - 0.0043 16.6 0.1 0.013 15.0 0.0 1.8 2 0 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 ORY12321.1 - 0.0093 16.6 0.9 0.016 15.8 0.9 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family LIP PF03583.14 ORY12321.1 - 0.022 14.1 0.2 0.12 11.7 0.0 2.0 2 0 0 2 2 2 0 Secretory lipase Hydrolase_4 PF12146.8 ORY12321.1 - 0.032 13.5 0.0 0.63 9.3 0.0 2.4 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Rpr2 PF04032.16 ORY12322.1 - 4.1e-22 78.3 0.1 8.9e-22 77.2 0.1 1.6 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain Mut7-C PF01927.16 ORY12322.1 - 0.03 14.4 0.4 0.064 13.4 0.2 1.6 1 1 0 1 1 1 0 Mut7-C RNAse domain HNH_5 PF14279.6 ORY12322.1 - 0.041 13.7 3.1 0.69 9.8 0.1 2.3 1 1 0 2 2 2 0 HNH endonuclease Lar_restr_allev PF14354.6 ORY12322.1 - 0.049 14.0 0.8 0.25 11.7 0.4 2.1 2 0 0 2 2 2 0 Restriction alleviation protein Lar GATA PF00320.27 ORY12322.1 - 0.064 12.9 1.5 0.22 11.2 0.1 2.4 2 0 0 2 2 2 0 GATA zinc finger zf-Sec23_Sec24 PF04810.15 ORY12322.1 - 0.091 12.8 0.3 5.6 7.1 0.0 2.3 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger DEAD PF00270.29 ORY12323.1 - 1.2e-36 126.1 0.1 2e-36 125.4 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY12323.1 - 2.6e-26 92.1 0.1 1.3e-23 83.4 0.1 2.5 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 ORY12323.1 - 6.1e-08 32.9 0.0 1.2e-07 31.8 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 ORY12323.1 - 0.00043 19.7 0.0 0.023 14.0 0.0 2.5 2 1 1 3 3 3 1 U3-containing 90S pre-ribosomal complex subunit Orbi_VP6 PF01516.16 ORY12323.1 - 0.19 11.2 0.0 0.28 10.6 0.0 1.2 1 0 0 1 1 1 0 Orbivirus helicase VP6 ApbA_C PF08546.11 ORY12326.1 - 9e-24 84.1 0.0 1.8e-23 83.1 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 ORY12326.1 - 9.1e-14 51.4 0.0 1.7e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Hexokinase_2 PF03727.16 ORY12328.1 - 3.8e-78 262.2 0.0 5.2e-78 261.8 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 ORY12328.1 - 1.5e-54 184.9 0.1 2.6e-54 184.2 0.1 1.4 1 0 0 1 1 1 1 Hexokinase DUF4131 PF13567.6 ORY12329.1 - 0.1 12.2 0.2 0.13 11.9 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) MFS_1 PF07690.16 ORY12331.1 - 9.6e-24 84.0 56.1 1.5e-16 60.3 30.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PALP PF00291.25 ORY12332.1 - 4e-54 184.0 0.5 4.8e-54 183.8 0.5 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme SKG6 PF08693.10 ORY12333.1 - 0.035 13.5 0.3 0.062 12.7 0.3 1.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain AdoMet_MTase PF07757.13 ORY12334.1 - 6e-34 116.7 0.0 2.2e-16 60.1 0.0 2.8 3 0 0 3 3 3 2 Predicted AdoMet-dependent methyltransferase Acetyltransf_1 PF00583.25 ORY12335.1 - 2.2e-11 44.0 0.1 2.9e-11 43.6 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ORY12335.1 - 5.8e-08 32.7 0.0 7.7e-08 32.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ORY12335.1 - 1.3e-07 31.9 0.1 1.9e-07 31.4 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain SEN1_N PF12726.7 ORY12337.1 - 7.3e-188 626.3 7.9 1.1e-187 625.7 7.9 1.3 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.6 ORY12337.1 - 2.3e-74 250.5 2.2 2.3e-74 250.5 2.2 2.7 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.6 ORY12337.1 - 1e-61 208.0 0.0 2.5e-61 206.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 ORY12337.1 - 2.8e-10 40.2 1.9 5.3e-06 26.3 0.2 3.2 3 0 0 3 3 3 2 AAA domain AAA_19 PF13245.6 ORY12337.1 - 1.9e-08 34.7 0.0 7.4e-08 32.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 ORY12337.1 - 2.5e-05 24.0 3.3 0.0017 17.9 0.1 3.3 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain Viral_helicase1 PF01443.18 ORY12337.1 - 2.9e-05 23.9 0.0 0.2 11.3 0.0 3.4 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DEAD PF00270.29 ORY12337.1 - 0.003 17.4 0.3 0.014 15.2 0.0 2.3 3 0 0 3 3 3 1 DEAD/DEAH box helicase T2SSE PF00437.20 ORY12337.1 - 0.0042 16.2 0.0 0.01 14.9 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein SMC_N PF02463.19 ORY12337.1 - 0.0097 15.4 0.0 1.9 7.8 0.1 2.7 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain ResIII PF04851.15 ORY12337.1 - 0.029 14.4 0.0 0.029 14.4 0.0 2.1 2 0 0 2 2 1 0 Type III restriction enzyme, res subunit AAA_16 PF13191.6 ORY12337.1 - 1 9.7 4.0 1.3 9.3 0.0 3.2 3 0 0 3 3 3 0 AAA ATPase domain DUF4407 PF14362.6 ORY12337.1 - 2.1 7.6 23.1 2.2 7.5 3.6 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4407) AAA_23 PF13476.6 ORY12337.1 - 8.7 6.8 18.6 0.099 13.1 0.6 2.8 3 0 0 3 3 2 0 AAA domain PhoLip_ATPase_C PF16212.5 ORY12339.1 - 5e-81 272.1 25.6 5e-81 272.1 25.6 2.3 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 ORY12339.1 - 1e-19 70.0 0.7 1e-19 70.0 0.7 2.4 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 ORY12339.1 - 2.3e-11 44.4 0.4 7.5e-06 26.4 0.2 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 ORY12339.1 - 8.8e-11 41.8 0.0 4.2e-10 39.6 0.0 2.1 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 ORY12339.1 - 3.9e-05 23.3 0.0 0.00044 19.8 0.0 2.6 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 ORY12339.1 - 0.019 14.7 0.2 0.04 13.6 0.2 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase TrbC PF04956.13 ORY12339.1 - 4.4 7.6 9.6 0.72 10.1 3.0 2.6 2 0 0 2 2 2 0 TrbC/VIRB2 family Tetraspanin PF00335.20 ORY12342.1 - 1.6e-05 24.7 11.7 2.8e-05 23.9 11.7 1.3 1 1 0 1 1 1 1 Tetraspanin family FeoB_C PF07664.12 ORY12342.1 - 1.4 8.7 4.3 11 5.7 0.0 3.5 4 0 0 4 4 4 0 Ferrous iron transport protein B C terminus DUF4131 PF13567.6 ORY12342.1 - 9.9 5.8 7.8 1.5 8.4 3.2 1.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) SRF-TF PF00319.18 ORY12344.1 - 3.8e-21 74.3 0.1 5.3e-21 73.8 0.1 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) AA_permease_2 PF13520.6 ORY12346.1 - 1.9e-56 191.7 57.3 2.4e-56 191.4 57.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ORY12346.1 - 2.7e-25 88.9 44.5 3.5e-25 88.5 44.5 1.0 1 0 0 1 1 1 1 Amino acid permease LapA_dom PF06305.11 ORY12346.1 - 5.7 6.8 8.5 1.8 8.4 2.3 3.3 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain bZIP_2 PF07716.15 ORY12347.1 - 6.9e-05 22.8 32.5 0.00047 20.2 4.1 4.8 1 1 4 5 5 5 2 Basic region leucine zipper ZapB PF06005.12 ORY12347.1 - 8.7e-05 22.9 29.2 0.0036 17.7 10.7 3.5 1 1 2 3 3 3 2 Cell division protein ZapB bZIP_1 PF00170.21 ORY12347.1 - 0.0032 17.5 27.2 1.1 9.4 6.6 4.1 1 1 3 4 4 4 4 bZIP transcription factor HALZ PF02183.18 ORY12347.1 - 0.097 12.9 21.8 1.9 8.8 6.6 3.5 2 1 1 3 3 3 0 Homeobox associated leucine zipper TSC22 PF01166.18 ORY12347.1 - 0.14 12.5 17.9 3.7 7.9 0.2 4.7 2 1 3 5 5 5 0 TSC-22/dip/bun family KASH_CCD PF14662.6 ORY12347.1 - 0.15 11.9 24.2 0.62 9.9 24.3 1.9 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH DivIC PF04977.15 ORY12347.1 - 0.54 10.1 31.4 1 9.1 4.3 4.0 1 1 3 4 4 4 0 Septum formation initiator YabA PF06156.13 ORY12347.1 - 0.62 10.7 18.3 3.3 8.4 11.1 2.9 1 1 2 3 3 3 0 Initiation control protein YabA Ax_dynein_light PF10211.9 ORY12347.1 - 0.68 9.8 24.0 0.099 12.6 10.0 2.1 1 1 1 2 2 2 0 Axonemal dynein light chain TMF_TATA_bd PF12325.8 ORY12347.1 - 1.1 9.6 20.2 0.26 11.5 2.2 2.9 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding GIT_CC PF16559.5 ORY12347.1 - 1.4 8.9 11.8 16 5.4 0.0 3.5 2 1 2 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor Atg14 PF10186.9 ORY12347.1 - 1.4 7.9 15.8 1.9 7.5 15.8 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4407 PF14362.6 ORY12347.1 - 2.5 7.4 14.9 3.4 6.9 14.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) LMBR1 PF04791.16 ORY12347.1 - 2.5 6.9 7.0 2.9 6.7 7.0 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein Exonuc_VII_L PF02601.15 ORY12347.1 - 2.8 7.4 9.3 3.5 7.1 9.3 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit CASP_C PF08172.12 ORY12347.1 - 4.3 6.6 15.5 0.39 10.0 10.4 1.8 2 1 0 2 2 2 0 CASP C terminal Cnn_1N PF07989.11 ORY12347.1 - 5.6 7.2 22.5 28 5.0 7.3 3.1 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 V_ATPase_I PF01496.19 ORY12347.1 - 6.4 4.6 9.2 7.4 4.4 9.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3450 PF11932.8 ORY12347.1 - 6.8 5.9 16.3 16 4.7 14.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF724 PF05266.14 ORY12347.1 - 8.8 6.1 15.5 13 5.5 15.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF724) Pup PF05639.11 ORY12347.1 - 9.1 7.3 12.0 1.7 9.6 4.6 2.4 1 1 1 2 2 2 0 Pup-like protein DUF347 PF03988.12 ORY12348.1 - 0.0008 19.5 0.5 0.0017 18.5 0.5 1.5 1 0 0 1 1 1 1 Repeat of Unknown Function (DUF347) GRA6 PF05084.13 ORY12348.1 - 0.012 15.5 0.1 0.021 14.8 0.1 1.3 1 0 0 1 1 1 0 Granule antigen protein (GRA6) TNFR_16_TM PF18422.1 ORY12348.1 - 0.093 12.7 0.1 0.2 11.6 0.1 1.5 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain Gram_pos_anchor PF00746.21 ORY12348.1 - 0.3 11.1 2.6 0.8 9.7 2.6 1.7 1 0 0 1 1 1 0 LPXTG cell wall anchor motif Cellulase PF00150.18 ORY12349.1 - 3.2e-45 154.7 0.3 6.7e-45 153.7 0.3 1.5 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) MIP-T3_C PF17749.1 ORY12349.1 - 0.21 11.6 0.0 0.36 10.8 0.0 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 C-terminal region HERV-K_REC PF15695.5 ORY12349.1 - 0.36 10.9 2.7 1.1 9.3 0.0 2.7 3 0 0 3 3 3 0 Rec (regulator of expression encoded by corf) of HERV-K-113 Reprolysin_5 PF13688.6 ORY12350.1 - 1e-59 202.0 11.7 1e-59 202.0 11.7 2.4 2 1 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 ORY12350.1 - 2.3e-49 168.0 7.5 5.7e-49 166.7 7.5 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 ORY12350.1 - 6.6e-44 150.0 6.3 1.1e-43 149.2 6.3 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.23 ORY12350.1 - 4.1e-16 59.5 33.8 4.1e-16 59.5 33.8 5.4 5 1 0 5 5 5 1 Disintegrin Reprolysin_3 PF13582.6 ORY12350.1 - 2.7e-13 50.5 0.3 8.8e-13 48.9 0.3 2.0 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like ADAM_CR_2 PF17771.1 ORY12350.1 - 0.00014 22.3 15.0 0.00014 22.3 15.0 5.4 1 1 2 3 3 3 1 ADAM cysteine-rich domain Pep_M12B_propep PF01562.19 ORY12350.1 - 0.02 15.1 0.1 0.23 11.7 0.0 2.5 3 1 0 3 3 3 0 Reprolysin family propeptide AMP-binding PF00501.28 ORY12351.1 - 3.9e-84 282.7 0.0 4.7e-84 282.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORY12351.1 - 2e-28 99.2 0.3 2.2e-26 92.6 0.4 2.7 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 ORY12351.1 - 1.1e-18 66.9 0.6 3.1e-18 65.4 0.6 1.8 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus WD40 PF00400.32 ORY12352.1 - 1.6e-20 73.0 14.5 1.5e-06 28.8 0.1 9.2 9 0 0 9 9 9 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY12352.1 - 4.6e-07 30.0 0.1 3.1 8.1 0.0 5.7 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Apolipoprotein PF01442.18 ORY12352.1 - 0.056 13.3 1.5 0.097 12.5 1.5 1.3 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Lactonase PF10282.9 ORY12352.1 - 0.13 11.5 0.0 2.1 7.5 0.0 2.2 2 0 0 2 2 2 0 Lactonase, 7-bladed beta-propeller MFS_1 PF07690.16 ORY12353.1 - 4.5e-32 111.3 59.3 6.5e-18 64.8 37.9 3.3 1 1 2 3 3 3 3 Major Facilitator Superfamily MFS_1_like PF12832.7 ORY12353.1 - 5.8e-10 38.6 5.4 9e-10 37.9 5.4 1.5 1 1 0 1 1 1 1 MFS_1 like family AAA PF00004.29 ORY12354.1 - 6.8e-41 139.8 0.0 8.4e-39 133.0 0.0 2.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 ORY12354.1 - 7.6e-08 32.0 1.2 2.4e-07 30.4 1.2 1.9 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 ORY12354.1 - 2.2e-05 24.3 0.0 5.5e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 ORY12354.1 - 6.6e-05 23.1 0.0 0.00018 21.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 ORY12354.1 - 0.00082 19.5 0.6 0.017 15.3 0.0 3.2 3 1 1 4 4 4 1 AAA domain AAA_5 PF07728.14 ORY12354.1 - 0.00086 19.3 0.0 0.0027 17.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 ORY12354.1 - 0.0011 19.0 0.0 0.004 17.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 ORY12354.1 - 0.0019 17.5 0.1 0.0039 16.4 0.1 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_16 PF13191.6 ORY12354.1 - 0.0019 18.6 0.3 0.0019 18.6 0.3 4.9 3 2 3 6 6 6 1 AAA ATPase domain AAA_18 PF13238.6 ORY12354.1 - 0.0024 18.4 0.0 0.011 16.2 0.0 2.3 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 ORY12354.1 - 0.0057 16.4 0.0 0.017 14.9 0.0 1.7 2 0 0 2 2 1 1 IstB-like ATP binding protein AAA_28 PF13521.6 ORY12354.1 - 0.0088 16.3 0.0 0.029 14.6 0.0 2.0 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 ORY12354.1 - 0.021 14.2 0.0 0.062 12.7 0.0 1.8 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 ORY12354.1 - 0.028 14.7 6.3 0.063 13.6 0.1 4.0 4 1 0 5 5 4 0 AAA domain DUF815 PF05673.13 ORY12354.1 - 0.035 13.3 0.0 0.062 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) TniB PF05621.11 ORY12354.1 - 0.041 13.3 0.1 19 4.6 0.0 3.3 4 0 0 4 4 4 0 Bacterial TniB protein RNA_helicase PF00910.22 ORY12354.1 - 0.042 14.2 0.0 0.13 12.7 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_30 PF13604.6 ORY12354.1 - 0.053 13.2 0.2 2.7 7.7 0.1 2.7 2 0 0 2 2 2 0 AAA domain IPT PF01745.16 ORY12354.1 - 0.056 12.8 0.3 0.78 9.1 0.1 2.3 2 0 0 2 2 2 0 Isopentenyl transferase PhoH PF02562.16 ORY12354.1 - 0.076 12.4 0.1 0.62 9.5 0.1 2.3 2 0 0 2 2 2 0 PhoH-like protein AAA_24 PF13479.6 ORY12354.1 - 0.09 12.5 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 ORY12354.1 - 0.11 11.5 0.0 0.21 10.6 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 TsaE PF02367.17 ORY12354.1 - 0.12 12.3 0.0 0.31 11.1 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Adaptin_binding PF10199.9 ORY12354.1 - 7.8 7.1 12.7 8.1 7.1 3.2 2.9 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 Ank_2 PF12796.7 ORY12355.1 - 4.7e-06 27.1 0.0 0.027 15.0 0.0 3.4 2 1 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY12355.1 - 9e-06 26.1 0.1 0.72 10.5 0.1 3.8 2 2 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY12355.1 - 1e-05 25.5 1.6 13 6.8 0.0 5.5 6 0 0 6 6 6 2 Ankyrin repeat Ank_5 PF13857.6 ORY12355.1 - 1.7e-05 25.0 0.1 0.35 11.3 0.0 3.6 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Mob1_phocein PF03637.17 ORY12356.1 - 5.8e-72 241.2 0.1 7.2e-72 240.9 0.1 1.0 1 0 0 1 1 1 1 Mob1/phocein family Glyco_hydro_63 PF03200.16 ORY12357.1 - 2.1e-07 30.1 8.2 5.9e-06 25.3 0.4 3.5 3 1 0 3 3 3 2 Glycosyl hydrolase family 63 C-terminal domain 1-cysPrx_C PF10417.9 ORY12357.1 - 0.34 10.8 1.8 0.71 9.8 1.8 1.5 1 0 0 1 1 1 0 C-terminal domain of 1-Cys peroxiredoxin SNAP-25 PF00835.19 ORY12357.1 - 0.58 10.5 2.6 0.74 10.2 0.0 2.3 2 0 0 2 2 2 0 SNAP-25 family zf-MYND PF01753.18 ORY12359.1 - 5.5e-10 39.2 18.7 1e-09 38.3 18.7 1.5 1 0 0 1 1 1 1 MYND finger Phage_tail_S PF05069.13 ORY12360.1 - 0.014 15.2 0.5 0.019 14.8 0.3 1.3 1 1 0 1 1 1 0 Phage virion morphogenesis family MFS_1 PF07690.16 ORY12361.1 - 3.3e-35 121.6 13.1 3.2e-34 118.4 14.3 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 ORY12361.1 - 1.9e-05 24.1 0.9 1.9e-05 24.1 0.9 1.9 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Cyt_c_ox_IV PF12270.8 ORY12361.1 - 0.49 10.5 0.1 0.49 10.5 0.1 2.9 3 0 0 3 3 3 0 Cytochrome c oxidase subunit IV DIOX_N PF14226.6 ORY12362.1 - 6.2e-18 65.7 0.0 1.2e-17 64.8 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 ORY12362.1 - 1.5e-11 44.7 0.0 3.1e-11 43.7 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Nfu_N PF08712.11 ORY12363.1 - 1.5e-29 101.9 0.0 2.4e-28 98.0 0.0 2.2 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.17 ORY12363.1 - 3.5e-27 94.3 0.1 5.7e-27 93.7 0.1 1.4 1 0 0 1 1 1 1 NifU-like domain LPMO_10 PF03067.15 ORY12364.1 - 0.00036 21.2 0.2 0.0012 19.6 0.2 1.8 1 1 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading PGA2 PF07543.12 ORY12365.1 - 8.6e-33 113.2 1.2 1.5e-32 112.5 1.2 1.4 1 1 0 1 1 1 1 Protein trafficking PGA2 CENP-S PF15630.6 ORY12366.1 - 1.9e-33 114.7 0.0 2.4e-33 114.3 0.0 1.1 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 ORY12366.1 - 1.4e-08 34.8 0.0 1.8e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Bromo_TP PF07524.13 ORY12366.1 - 0.0087 16.0 0.1 0.012 15.5 0.1 1.3 1 0 0 1 1 1 1 Bromodomain associated TFIID-18kDa PF02269.16 ORY12366.1 - 0.05 13.6 0.0 0.064 13.3 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit Glyco_transf_88 PF16849.5 ORY12366.1 - 0.06 12.3 0.0 0.071 12.0 0.0 1.0 1 0 0 1 1 1 0 Glycosyltransferase family 88 TFIID-31kDa PF02291.15 ORY12366.1 - 0.083 13.0 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit MARVEL PF01284.23 ORY12367.1 - 0.0019 18.2 12.6 0.003 17.6 12.6 1.3 1 0 0 1 1 1 1 Membrane-associating domain DUF2530 PF10745.9 ORY12367.1 - 2.7 8.3 10.8 2.8 8.2 2.4 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF2530) Peptidase_U4 PF03419.13 ORY12367.1 - 6.7 5.9 8.8 99 2.1 8.9 2.1 1 1 0 1 1 1 0 Sporulation factor SpoIIGA ADH_N PF08240.12 ORY12368.1 - 1.2e-30 105.5 0.5 3e-30 104.3 0.5 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORY12368.1 - 2.4e-28 98.7 0.1 4e-28 98.0 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ORY12368.1 - 5.8e-07 30.6 0.0 9.8e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 ORY12368.1 - 1.4e-06 27.9 0.1 2e-06 27.5 0.1 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus NAD_binding_7 PF13241.6 ORY12368.1 - 0.00095 19.6 0.4 0.0017 18.8 0.4 1.3 1 0 0 1 1 1 1 Putative NAD(P)-binding TrkA_N PF02254.18 ORY12368.1 - 0.0011 19.2 0.1 0.0028 17.9 0.0 1.7 2 0 0 2 2 2 1 TrkA-N domain ADH_N_assoc PF13823.6 ORY12368.1 - 0.0025 17.7 0.1 0.0063 16.4 0.1 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated Shikimate_DH PF01488.20 ORY12368.1 - 0.0061 16.6 0.0 0.014 15.5 0.0 1.6 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 ORY12368.1 - 0.03 14.6 0.2 0.053 13.8 0.2 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Pyr_redox_2 PF07992.14 ORY12368.1 - 0.041 13.1 1.0 0.11 11.7 0.1 1.8 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_3 PF03447.16 ORY12368.1 - 0.074 13.7 0.1 0.14 12.8 0.1 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain F420_oxidored PF03807.17 ORY12368.1 - 0.074 13.6 0.0 0.14 12.8 0.0 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Pyr_redox PF00070.27 ORY12368.1 - 0.085 13.4 0.5 0.37 11.4 0.5 2.1 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ORY12368.1 - 0.11 11.8 0.2 0.17 11.1 0.2 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ADH_N PF08240.12 ORY12369.1 - 5.2e-24 84.2 2.2 9.6e-24 83.4 2.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORY12369.1 - 4.8e-15 55.7 0.0 9.9e-15 54.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 ORY12369.1 - 0.017 14.4 0.2 0.053 12.8 0.0 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 ORY12369.1 - 0.13 11.6 0.1 0.23 10.8 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Ctf8 PF09696.10 ORY12370.1 - 9.3e-42 142.7 0.0 1.6e-41 142.0 0.0 1.3 1 1 0 1 1 1 1 Ctf8 CBM_1 PF00734.18 ORY12371.1 - 1.4e-08 34.5 7.8 1.4e-08 34.5 7.8 2.3 3 0 0 3 3 3 1 Fungal cellulose binding domain DUF3455 PF11937.8 ORY12372.1 - 2.4e-37 128.7 0.1 3.1e-37 128.4 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) adh_short PF00106.25 ORY12373.1 - 9.2e-25 87.2 0.0 6.1e-24 84.6 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY12373.1 - 2.6e-17 63.2 0.0 1.1e-16 61.2 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 ORY12373.1 - 9e-05 22.0 0.0 0.00019 21.0 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 ORY12373.1 - 0.0014 18.6 0.1 0.0024 17.8 0.1 1.3 1 0 0 1 1 1 1 KR domain 2-Hacid_dh_C PF02826.19 ORY12373.1 - 0.05 13.0 0.0 0.074 12.4 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 ORY12373.1 - 0.12 12.3 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding Fungal_lectin_2 PF18647.1 ORY12385.1 - 1.2e-08 35.4 0.3 1.3e-07 31.9 0.1 2.2 2 1 0 2 2 2 1 Alpha-galactosyl-binding fungal lectin Pkinase PF00069.25 ORY12388.1 - 5.3e-41 140.7 0.0 8.3e-41 140.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY12388.1 - 2.7e-23 82.6 0.0 4.4e-23 81.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HET PF06985.11 ORY12388.1 - 1.5e-13 51.3 0.8 1.5e-13 51.3 0.8 2.8 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Myb_DNA-bind_2 PF08914.11 ORY12388.1 - 0.044 14.0 0.1 0.9 9.8 0.2 2.7 2 0 0 2 2 2 0 Rap1 Myb domain Fungal_trans PF04082.18 ORY12389.1 - 9.3e-28 97.0 0.2 2.1e-27 95.8 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY12389.1 - 8.4e-09 35.4 10.1 1.5e-08 34.6 10.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SlyX PF04102.12 ORY12389.1 - 0.09 13.4 0.9 0.21 12.2 0.9 1.6 1 0 0 1 1 1 0 SlyX UDPGP PF01704.18 ORY12390.1 - 1.4e-57 195.3 0.0 1.9e-57 194.8 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase MR_MLE_C PF13378.6 ORY12390.1 - 1.1e-42 146.1 0.0 2.1e-42 145.2 0.0 1.4 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 ORY12390.1 - 7.4e-08 32.6 0.0 1.6e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Fer4_20 PF14691.6 ORY12390.1 - 0.06 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster HHH_5 PF14520.6 ORY12392.1 - 9.1e-07 29.4 0.6 1.5e-06 28.7 0.6 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix domain Rad51 PF08423.11 ORY12392.1 - 0.00016 21.1 0.1 0.00026 20.4 0.1 1.3 1 0 0 1 1 1 1 Rad51 RNA_pol_A_CTD PF03118.15 ORY12392.1 - 0.18 11.6 0.0 0.29 10.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial RNA polymerase, alpha chain C terminal domain Tyrosinase PF00264.20 ORY12393.1 - 4.6e-46 157.9 6.3 6.1e-46 157.5 6.3 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase EthD PF07110.11 ORY12394.1 - 0.00021 22.3 0.5 0.85 10.8 0.1 2.5 2 1 0 2 2 2 2 EthD domain Mvb12 PF09452.10 ORY12394.1 - 0.021 15.2 0.0 0.61 10.5 0.0 2.4 2 0 0 2 2 2 0 ESCRT-I subunit Mvb12 DUF4286 PF14114.6 ORY12394.1 - 0.029 14.8 1.8 2 8.9 0.5 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4286) BTB PF00651.31 ORY12395.1 - 9.2e-08 32.3 0.1 3.9e-07 30.3 0.0 2.0 2 0 0 2 2 2 1 BTB/POZ domain PCI PF01399.27 ORY12396.1 - 2.5e-06 27.9 0.0 4.6e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 PCI domain PPR PF01535.20 ORY12396.1 - 0.13 12.6 0.0 0.38 11.1 0.0 1.7 1 0 0 1 1 1 0 PPR repeat TPR_2 PF07719.17 ORY12396.1 - 0.21 11.8 0.9 37 4.8 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Ribosomal_L18A PF01775.17 ORY12397.1 - 3.1e-54 182.2 0.3 4.1e-54 181.8 0.3 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A EHN PF06441.12 ORY12398.1 - 1.8e-33 115.1 0.2 3.5e-33 114.2 0.2 1.5 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 ORY12398.1 - 9.5e-09 35.3 0.0 1.8e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORY12398.1 - 0.016 15.8 0.5 0.033 14.8 0.5 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family Histidinol_dh PF00815.20 ORY12399.1 - 3.6e-158 526.9 2.1 4.8e-158 526.5 2.1 1.2 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.18 ORY12399.1 - 1.1e-24 86.0 0.1 2e-24 85.2 0.1 1.4 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.17 ORY12399.1 - 1.5e-14 54.1 0.3 5.9e-14 52.3 0.1 2.1 2 0 0 2 2 2 1 Phosphoribosyl-ATP pyrophosphohydrolase MazG PF03819.17 ORY12399.1 - 0.0039 17.3 0.5 0.041 14.1 0.2 2.6 3 0 0 3 3 3 1 MazG nucleotide pyrophosphohydrolase domain Glyco_hydro_10 PF00331.20 ORY12400.1 - 3.2e-102 341.9 0.1 4.5e-102 341.4 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_1 PF00734.18 ORY12400.1 - 8.4e-12 44.8 15.4 8.4e-12 44.8 15.4 2.3 2 0 0 2 2 2 1 Fungal cellulose binding domain Glyco_hydro_42 PF02449.15 ORY12400.1 - 0.14 11.5 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Beta-galactosidase ECH_1 PF00378.20 ORY12401.1 - 8.8e-42 143.1 0.0 1.1e-41 142.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ORY12401.1 - 6.4e-22 78.5 0.4 8.1e-22 78.2 0.4 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ADH_N PF08240.12 ORY12402.1 - 2.3e-27 95.0 2.0 6e-27 93.7 2.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORY12402.1 - 2.8e-07 30.6 0.0 6.4e-05 22.9 0.0 2.4 2 0 0 2 2 2 2 Zinc-binding dehydrogenase ADH_N_assoc PF13823.6 ORY12402.1 - 0.00011 22.0 3.5 0.00015 21.6 2.1 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-associated PglD_N PF17836.1 ORY12402.1 - 0.11 13.1 0.0 0.26 12.0 0.0 1.6 1 0 0 1 1 1 0 PglD N-terminal domain tRNA-synt_2 PF00152.20 ORY12403.1 - 1.9e-56 191.5 0.0 2.4e-56 191.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 ORY12403.1 - 1.2e-07 31.6 0.0 2.4e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 ORY12403.1 - 3.1e-07 30.2 0.0 7.8e-05 22.3 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Methyltransf_16 PF10294.9 ORY12404.1 - 0.068 12.9 0.0 0.76 9.5 0.0 2.0 2 0 0 2 2 2 0 Lysine methyltransferase HLH PF00010.26 ORY12405.1 - 5.9e-09 35.8 0.1 1.2e-08 34.8 0.1 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Membr_traf_MHD PF10540.9 ORY12406.1 - 9.4e-23 81.0 2.8 6.3e-20 71.9 2.8 2.6 1 1 0 1 1 1 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.30 ORY12406.1 - 1.6e-15 57.3 0.0 3.5e-15 56.2 0.0 1.6 1 0 0 1 1 1 1 C2 domain DUF810 PF05664.11 ORY12406.1 - 4.7e-06 25.4 1.1 5.5e-06 25.2 0.2 1.5 2 0 0 2 2 2 1 Plant family of unknown function (DUF810) Ras PF00071.22 ORY12407.1 - 1.4e-40 138.5 0.0 1.9e-40 138.1 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY12407.1 - 4e-28 98.0 0.0 5.9e-28 97.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY12407.1 - 6.6e-11 42.0 0.0 3.5e-10 39.6 0.0 1.9 2 0 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 ORY12407.1 - 0.001 18.5 0.0 0.0014 18.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 ORY12407.1 - 0.0011 18.6 0.0 0.0034 17.0 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 ORY12407.1 - 0.0021 18.1 0.0 0.0035 17.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 ORY12407.1 - 0.0051 16.6 0.0 3.8 7.2 0.0 2.3 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 ORY12407.1 - 0.039 13.9 0.0 0.1 12.5 0.0 1.7 2 0 0 2 2 2 0 RsgA GTPase ABC_tran PF00005.27 ORY12407.1 - 0.06 13.9 0.0 0.11 13.1 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 ORY12407.1 - 0.083 13.2 0.0 0.98 9.7 0.0 2.3 1 1 0 2 2 2 0 AAA domain zf-CCHC PF00098.23 ORY12409.1 - 6.3e-41 136.7 67.7 1.1e-07 31.6 3.8 7.3 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.6 ORY12409.1 - 8.3e-11 41.4 41.7 0.054 13.2 0.5 7.4 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_6 PF15288.6 ORY12409.1 - 0.00066 19.5 1.2 0.00066 19.5 1.2 7.4 6 1 1 7 7 7 4 Zinc knuckle E1-E2_ATPase PF00122.20 ORY12410.1 - 5.4e-49 166.2 2.0 5.4e-49 166.2 2.0 2.2 2 0 0 2 2 2 1 E1-E2 ATPase HMA PF00403.26 ORY12410.1 - 7.5e-40 135.2 3.5 1.4e-12 47.9 0.1 4.3 4 0 0 4 4 4 3 Heavy-metal-associated domain Hydrolase PF00702.26 ORY12410.1 - 8.6e-33 114.4 3.2 9.2e-33 114.3 0.7 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 ORY12410.1 - 7.3e-05 22.6 0.7 0.0031 17.3 0.2 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase zinc_ribbon_12 PF11331.8 ORY12410.1 - 0.027 14.3 1.0 22 4.9 0.0 3.5 3 0 0 3 3 3 0 Probable zinc-ribbon domain DUF678 PF05077.12 ORY12410.1 - 0.1 12.8 3.8 2 8.6 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF678) DSBA PF01323.20 ORY12410.1 - 0.21 11.3 0.5 81 2.9 0.0 3.7 4 0 0 4 4 4 0 DSBA-like thioredoxin domain Fer2_BFD PF04324.15 ORY12410.1 - 7.5 7.0 8.6 76 3.8 0.2 4.6 4 0 0 4 4 4 0 BFD-like [2Fe-2S] binding domain PCI PF01399.27 ORY12411.1 - 4.3e-07 30.4 0.0 7.7e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 PCI domain CSN7a_helixI PF18392.1 ORY12411.1 - 0.023 14.6 0.0 0.043 13.7 0.0 1.5 1 0 0 1 1 1 0 COP9 signalosome complex subunit 7a helix I domain Lactamase_B_2 PF12706.7 ORY12413.1 - 5e-09 36.0 0.0 4.2e-08 33.0 0.0 2.3 2 1 0 2 2 2 1 Beta-lactamase superfamily domain DRMBL PF07522.14 ORY12413.1 - 2.6e-06 27.6 0.0 5.6e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B PF00753.27 ORY12413.1 - 5.4e-05 23.3 0.0 8.3e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily RMMBL PF07521.12 ORY12413.1 - 0.13 12.2 0.0 0.32 11.0 0.0 1.6 1 0 0 1 1 1 0 Zn-dependent metallo-hydrolase RNA specificity domain PAF-AH_p_II PF03403.13 ORY12414.1 - 2.9e-45 154.4 0.0 9.8e-45 152.7 0.0 1.7 1 1 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 ORY12414.1 - 1.4e-08 34.0 0.1 5.2e-08 32.1 0.1 1.8 1 1 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 ORY12414.1 - 5.8e-06 25.5 0.0 1.1e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Chlorophyllase Hydrolase_4 PF12146.8 ORY12414.1 - 0.00022 20.6 0.1 0.0039 16.5 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DLH PF01738.18 ORY12414.1 - 0.013 15.1 0.0 0.023 14.3 0.0 1.4 1 0 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 ORY12414.1 - 0.12 12.0 0.0 0.34 10.5 0.0 1.8 2 0 0 2 2 2 0 alpha/beta hydrolase fold SAD_SRA PF02182.17 ORY12415.1 - 7.8e-34 116.6 0.2 1.5e-33 115.7 0.2 1.5 1 0 0 1 1 1 1 SAD/SRA domain DUF4407 PF14362.6 ORY12415.1 - 1.4 8.2 6.6 3 7.1 6.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Sel1 PF08238.12 ORY12417.1 - 6.3e-37 125.2 38.2 2.8e-06 27.8 0.2 11.3 12 0 0 12 12 12 8 Sel1 repeat TPR_7 PF13176.6 ORY12417.1 - 4.3e-05 23.3 4.2 1.4 9.1 0.3 4.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 ORY12417.1 - 0.0051 17.5 13.6 0.88 10.6 1.3 5.5 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 ORY12417.1 - 0.0054 16.8 1.5 8 7.0 0.0 5.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 ORY12417.1 - 0.017 15.7 21.9 0.31 11.7 1.2 6.4 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_19 PF14559.6 ORY12417.1 - 0.034 14.6 10.3 2.4 8.7 0.4 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 ORY12417.1 - 0.047 13.5 9.8 0.47 10.4 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat SARAF PF06682.12 ORY12417.1 - 0.076 12.6 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis DUF2615 PF11027.8 ORY12417.1 - 0.077 13.1 0.0 0.67 10.1 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2615) TPR_6 PF13174.6 ORY12417.1 - 0.44 11.3 23.9 0.73 10.6 0.0 7.8 10 1 0 10 10 10 0 Tetratricopeptide repeat MFS_1 PF07690.16 ORY12418.1 - 1.3e-39 136.1 49.8 1.3e-39 136.1 49.8 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY12418.1 - 6.2e-11 41.8 13.5 6.2e-11 41.8 13.5 2.7 2 1 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 ORY12418.1 - 7 4.8 14.4 0.035 12.4 3.3 2.2 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family tRNA-synt_2b PF00587.25 ORY12420.1 - 9.6e-36 123.4 0.0 2.6e-34 118.8 0.0 2.1 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 ORY12420.1 - 1.2e-07 31.7 0.0 3e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain BTB PF00651.31 ORY12421.1 - 0.02 15.1 0.0 0.043 14.0 0.0 1.5 1 0 0 1 1 1 0 BTB/POZ domain Podoplanin PF05808.11 ORY12422.1 - 0.0033 17.6 0.0 0.0046 17.1 0.0 1.3 1 0 0 1 1 1 1 Podoplanin SKG6 PF08693.10 ORY12422.1 - 0.035 13.5 0.0 0.035 13.5 0.0 2.0 2 0 0 2 2 2 0 Transmembrane alpha-helix domain DUF4690 PF15756.5 ORY12422.1 - 0.075 13.6 3.7 0.14 12.8 1.2 2.1 2 0 0 2 2 2 0 Small Novel Rich in Cartilage Phage_HK97_TLTM PF06120.11 ORY12422.1 - 0.36 10.0 0.3 0.52 9.4 0.3 1.1 1 0 0 1 1 1 0 Tail length tape measure protein Pex14_N PF04695.13 ORY12422.1 - 9.6 6.8 10.2 0.35 11.5 1.4 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region BTB PF00651.31 ORY12424.1 - 0.0056 16.9 0.0 0.0073 16.5 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain LysM PF01476.20 ORY12426.1 - 1.3e-15 57.2 2.3 8.4e-06 25.8 0.0 4.7 4 1 1 5 5 5 4 LysM domain LysM PF01476.20 ORY12427.1 - 1.3e-22 79.6 0.5 7.9e-07 29.0 0.0 4.9 4 0 0 4 4 4 4 LysM domain Glyco_hydro_18 PF00704.28 ORY12428.1 - 7.5e-79 265.7 0.1 1.5e-78 264.7 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 ORY12428.1 - 2.3e-11 43.9 18.9 2.3e-11 43.9 18.9 5.0 5 0 0 5 5 5 2 Chitin recognition protein Sulfate_transp PF00916.20 ORY12429.1 - 2.9e-114 381.8 23.4 3.5e-114 381.5 23.4 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 ORY12429.1 - 4.4e-08 32.8 0.0 9.3e-08 31.7 0.0 1.5 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 ORY12429.1 - 3.8e-06 27.3 16.0 3e-05 24.4 5.1 3.0 2 1 0 2 2 2 2 Molybdate transporter of MFS superfamily F-box-like PF12937.7 ORY12430.1 - 0.00014 21.7 1.0 0.00014 21.7 1.0 2.4 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 ORY12430.1 - 0.027 14.3 3.6 0.029 14.2 1.0 2.4 2 0 0 2 2 2 0 F-box domain F-box-like_2 PF13013.6 ORY12430.1 - 0.038 13.9 0.2 0.098 12.6 0.2 1.8 1 0 0 1 1 1 0 F-box-like domain GFA PF04828.14 ORY12431.1 - 0.026 14.8 0.0 0.061 13.7 0.0 1.6 1 0 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme DZR PF12773.7 ORY12431.1 - 0.091 12.8 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Double zinc ribbon zinc_ribbon_2 PF13240.6 ORY12431.1 - 0.096 12.4 0.3 0.22 11.3 0.3 1.6 1 0 0 1 1 1 0 zinc-ribbon domain AA_permease_2 PF13520.6 ORY12433.1 - 1.6e-47 162.3 48.3 2e-47 162.0 48.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ORY12433.1 - 5.7e-22 78.0 41.9 7.9e-22 77.5 41.9 1.1 1 0 0 1 1 1 1 Amino acid permease DUF2593 PF10767.9 ORY12435.1 - 0.014 15.5 0.2 0.029 14.4 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2593) UL97 PF06734.12 ORY12438.1 - 0.11 12.3 0.1 0.18 11.7 0.1 1.3 1 0 0 1 1 1 0 UL97 Abhydrolase_1 PF00561.20 ORY12439.1 - 1.4e-16 61.0 0.5 5.5e-15 55.7 0.5 2.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORY12439.1 - 2.1e-14 54.7 0.4 2.5e-14 54.4 0.4 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORY12439.1 - 5.8e-07 29.0 0.0 8.2e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 ORY12439.1 - 0.0036 16.0 0.0 0.0053 15.5 0.0 1.2 1 0 0 1 1 1 1 Ndr family Abhydrolase_4 PF08386.10 ORY12439.1 - 0.13 12.4 0.0 0.33 11.1 0.0 1.7 2 0 0 2 2 2 0 TAP-like protein DUF16 PF01519.16 ORY12440.1 - 0.076 13.5 0.7 0.11 12.9 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF16 Tau95 PF09734.9 ORY12440.1 - 0.31 11.9 3.9 1.2 10.0 3.9 1.9 1 1 0 1 1 1 0 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain TPR_10 PF13374.6 ORY12441.1 - 9.3e-36 120.7 1.3 5.2e-07 29.3 0.0 7.2 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_12 PF13424.6 ORY12441.1 - 1e-32 112.2 0.7 8.9e-09 35.5 0.0 5.7 3 2 3 6 6 6 6 Tetratricopeptide repeat Clr5 PF14420.6 ORY12441.1 - 1.2e-15 57.4 0.1 3.8e-15 55.9 0.1 1.8 1 0 0 1 1 1 1 Clr5 domain TPR_7 PF13176.6 ORY12441.1 - 1.4e-06 27.9 2.0 4.5 7.5 0.1 5.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 ORY12441.1 - 4e-06 27.4 1.1 0.002 18.8 0.8 4.0 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 ORY12441.1 - 9.3e-06 25.7 0.9 0.0041 17.4 0.0 3.2 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 ORY12441.1 - 0.00025 20.9 0.4 0.14 12.4 0.1 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 ORY12441.1 - 0.0012 19.4 1.1 1.9 9.5 0.3 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_MalT PF17874.1 ORY12441.1 - 0.0016 17.9 0.3 0.21 10.9 0.0 2.4 1 1 0 2 2 2 1 MalT-like TPR region TPR_1 PF00515.28 ORY12441.1 - 0.0022 17.7 0.1 1.7 8.6 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 ORY12441.1 - 0.0063 17.0 0.1 76 3.9 0.0 4.2 3 2 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 ORY12441.1 - 0.13 13.0 3.4 1.2 10.0 0.6 2.9 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 ORY12441.1 - 0.14 12.4 0.2 0.99 9.8 0.0 2.6 4 0 0 4 4 4 0 Tetratricopeptide repeat RRM_1 PF00076.22 ORY12442.1 - 0.0031 17.3 0.3 0.25 11.2 0.0 2.7 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2867 PF11066.8 ORY12445.1 - 0.14 12.5 0.0 0.16 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2867) Tyrosinase PF00264.20 ORY12449.1 - 1.2e-34 120.6 1.9 2e-34 119.8 1.9 1.4 1 0 0 1 1 1 1 Common central domain of tyrosinase NAD_binding_1 PF00175.21 ORY12451.1 - 1.3e-33 115.9 0.0 2.3e-33 115.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 ORY12451.1 - 3e-23 82.0 0.0 6.4e-23 81.0 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 ORY12451.1 - 1e-07 32.2 0.0 0.00035 20.7 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 ORY12451.1 - 0.0067 16.6 0.0 0.017 15.3 0.0 1.6 2 0 0 2 2 2 1 Siderophore-interacting FAD-binding domain NACHT PF05729.12 ORY12452.1 - 3e-05 24.0 0.6 7.2e-05 22.8 0.4 1.8 1 1 0 1 1 1 1 NACHT domain KAP_NTPase PF07693.14 ORY12452.1 - 5.1e-05 22.7 0.0 9.2e-05 21.8 0.0 1.4 1 0 0 1 1 1 1 KAP family P-loop domain AAA_16 PF13191.6 ORY12452.1 - 0.0015 18.9 0.0 0.0032 17.9 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 ORY12452.1 - 0.023 15.0 0.1 0.12 12.7 0.0 2.1 2 1 0 2 2 2 0 AAA domain DUF4004 PF13171.6 ORY12452.1 - 0.13 12.5 0.6 5.3 7.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4004) AAA PF00004.29 ORY12452.1 - 0.16 12.4 0.3 1.5 9.2 0.3 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 ORY12452.1 - 0.18 11.5 0.0 0.32 10.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain Gram_pos_anchor PF00746.21 ORY12454.1 - 0.081 12.9 2.7 0.24 11.4 2.7 1.9 1 0 0 1 1 1 0 LPXTG cell wall anchor motif DUF5305 PF17231.2 ORY12454.1 - 0.14 11.6 2.8 4.3 6.7 0.0 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5305) TFIIA PF03153.13 ORY12454.1 - 2.7 7.9 10.0 3.9 7.3 10.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MFS_1 PF07690.16 ORY12455.1 - 4.1e-43 147.7 27.5 4.1e-43 147.7 27.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY12455.1 - 6e-12 45.2 9.3 6e-12 45.2 9.3 2.2 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 ORY12455.1 - 0.00019 20.0 7.0 0.00043 18.8 6.2 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.7 ORY12455.1 - 0.0005 19.0 1.7 0.0005 19.0 1.7 2.5 3 0 0 3 3 3 1 MFS_1 like family MFS_3 PF05977.13 ORY12455.1 - 0.00085 17.8 0.2 0.00085 17.8 0.2 1.8 2 0 0 2 2 2 1 Transmembrane secretion effector T5orf172 PF10544.9 ORY12457.1 - 1.5e-22 80.1 0.8 4e-22 78.7 0.8 1.8 1 0 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 ORY12457.1 - 5.5e-18 65.4 0.8 1.4e-17 64.1 0.8 1.8 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 Glyco_hydro_43 PF04616.14 ORY12458.1 - 1.7e-16 60.4 7.6 1.1e-09 38.0 5.1 2.3 1 1 1 2 2 2 2 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 ORY12458.1 - 2.4e-09 37.2 0.4 1.2e-08 34.9 0.0 2.4 2 1 0 2 2 2 1 Beta xylosidase C-terminal Concanavalin A-like domain SCNM1_acidic PF15805.5 ORY12458.1 - 0.61 9.9 2.3 0.67 9.7 0.0 2.2 3 0 0 3 3 3 0 Acidic C-terminal region of sodium channel modifier 1 SCNM1 T5orf172 PF10544.9 ORY12459.1 - 1.3e-18 67.4 0.5 4e-18 65.9 0.5 1.9 1 0 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 ORY12459.1 - 1.1e-10 42.0 2.3 1.1e-10 42.0 0.5 2.0 2 0 0 2 2 2 1 Meiotically up-regulated gene 113 DUF3435 PF11917.8 ORY12460.1 - 0.0066 15.4 0.0 0.0089 15.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) AWS PF17907.1 ORY12461.1 - 4e-08 33.2 7.7 9.4e-08 32.0 7.7 1.7 1 0 0 1 1 1 1 AWS domain SET PF00856.28 ORY12461.1 - 0.0018 18.7 1.6 1.4 9.3 0.0 2.5 2 1 1 3 3 3 2 SET domain zf-H2C2_2 PF13465.6 ORY12462.1 - 9.8e-06 25.8 4.7 0.022 15.2 0.4 2.5 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 ORY12462.1 - 2.5e-05 24.5 17.0 7.9e-05 22.9 5.5 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY12462.1 - 0.00016 22.2 15.2 0.0076 17.0 4.5 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 ORY12462.1 - 0.071 12.9 2.1 0.071 12.9 2.1 2.1 2 0 0 2 2 2 0 zinc-finger C2H2-type DUF1922 PF09082.10 ORY12462.1 - 1.1 9.6 6.4 20 5.6 6.4 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF1922) zf-C2H2_6 PF13912.6 ORY12462.1 - 4 7.6 10.1 2.8 8.0 4.9 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger HET PF06985.11 ORY12465.1 - 0.078 13.3 0.2 0.14 12.6 0.2 1.4 1 0 0 1 1 1 0 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.7 ORY12466.1 - 6.3e-26 90.8 5.2 2.6e-15 56.8 0.3 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY12466.1 - 2.6e-24 85.3 3.5 7.6e-11 42.3 0.1 4.4 1 1 4 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 ORY12466.1 - 6.8e-20 70.6 3.0 0.00055 20.3 0.1 5.0 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.6 ORY12466.1 - 4.8e-12 44.9 0.6 0.13 12.9 0.0 4.7 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 ORY12466.1 - 9.1e-11 41.8 1.2 0.0027 18.0 0.1 3.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 ORY12468.1 - 3.8e-19 69.0 0.0 2.9e-13 50.2 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ORY12468.1 - 5.3e-18 63.3 0.0 1.5e-05 25.0 0.0 3.5 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 ORY12468.1 - 3e-17 62.7 0.0 5.2e-11 42.8 0.0 3.0 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 ORY12468.1 - 6.6e-16 58.2 0.1 1.2e-09 38.2 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 ORY12468.1 - 3.3e-15 55.7 0.0 1.4e-05 25.3 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat VWA_3_C PF18571.1 ORY12468.1 - 0.011 15.6 2.1 1.5 8.7 0.3 3.2 3 0 0 3 3 3 0 von Willebrand factor type A C-terminal domain SchA_CurD PF04486.12 ORY12468.1 - 0.011 15.8 0.0 3 8.0 0.0 2.5 2 1 1 3 3 3 0 SchA/CurD like domain MBT PF02820.18 ORY12468.1 - 0.018 15.3 0.1 31 5.0 0.0 3.1 3 0 0 3 3 3 0 mbt repeat Imm_superinfect PF14373.6 ORY12468.1 - 0.15 12.0 3.1 3.9 7.5 0.0 3.3 4 0 0 4 4 4 0 Superinfection immunity protein DNA_ligase_IV PF11411.8 ORY12468.1 - 0.53 10.5 2.9 9.4 6.5 0.1 2.5 2 0 0 2 2 2 0 DNA ligase IV DUF4869 PF16163.5 ORY12490.1 - 0.11 12.3 0.1 0.16 11.7 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4869) Dioxygenase_C PF00775.21 ORY12491.1 - 5.7e-46 156.2 0.0 7.8e-46 155.8 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 ORY12491.1 - 1.4e-25 88.9 0.1 2.1e-25 88.4 0.1 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 ORY12491.1 - 0.00024 21.3 0.0 0.0007 19.8 0.0 1.7 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain Lipase_C PF18067.1 ORY12491.1 - 0.034 14.7 0.0 0.14 12.8 0.0 2.0 2 0 0 2 2 2 0 Lipase C-terminal domain TPP_enzyme_N PF02776.18 ORY12492.1 - 7.2e-34 116.9 0.0 1.2e-33 116.1 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 ORY12492.1 - 2.4e-17 62.9 0.0 6e-17 61.7 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 ORY12492.1 - 2.9e-13 49.9 1.2 2.8e-11 43.5 0.3 2.8 2 1 0 2 2 2 2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain SIS PF01380.22 ORY12492.1 - 0.13 12.1 0.1 8.9 6.2 0.0 2.9 3 0 0 3 3 3 0 SIS domain Rad51 PF08423.11 ORY12493.1 - 4.3e-05 22.9 0.0 0.00058 19.2 0.0 2.3 2 1 0 2 2 2 1 Rad51 DUF3801 PF12687.7 ORY12493.1 - 0.024 14.7 0.0 0.035 14.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3801) RecA PF00154.21 ORY12493.1 - 0.029 13.9 0.0 0.043 13.3 0.0 1.2 1 0 0 1 1 1 0 recA bacterial DNA recombination protein Med31 PF05669.12 ORY12494.1 - 1.4e-33 114.8 2.8 1.6e-33 114.6 2.8 1.0 1 0 0 1 1 1 1 SOH1 Pal1 PF08316.11 ORY12495.1 - 1.1e-45 155.8 1.4 2.2e-45 154.8 0.4 2.1 2 0 0 2 2 2 1 Pal1 cell morphology protein P3A PF08727.11 ORY12495.1 - 0.25 10.7 0.5 0.74 9.2 0.5 1.7 1 0 0 1 1 1 0 Poliovirus 3A protein like RabGAP-TBC PF00566.18 ORY12496.1 - 1.1e-31 110.2 0.0 1.8e-31 109.5 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Herpes_UL6 PF01763.16 ORY12496.1 - 0.42 9.1 1.4 0.62 8.5 1.4 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like Stb3 PF10330.9 ORY12497.1 - 3.7e-24 84.6 0.1 7.4e-24 83.6 0.1 1.5 1 0 0 1 1 1 1 Putative Sin3 binding protein Topoisom_bac PF01131.20 ORY12498.1 - 1.3e-105 353.8 0.0 4.9e-99 332.1 0.0 2.1 2 0 0 2 2 2 2 DNA topoisomerase Toprim PF01751.22 ORY12498.1 - 4.8e-18 65.3 0.0 1.8e-17 63.5 0.0 2.0 2 0 0 2 2 2 1 Toprim domain DUF1295 PF06966.12 ORY12499.1 - 5.9e-34 117.6 11.2 7.3e-34 117.3 11.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.14 ORY12499.1 - 0.0032 17.9 1.6 0.14 12.6 0.1 2.8 2 1 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Peroxin-13_N PF04088.13 ORY12499.1 - 0.12 12.7 0.0 0.25 11.6 0.0 1.5 1 0 0 1 1 1 0 Peroxin 13, N-terminal region DUF2157 PF09925.9 ORY12499.1 - 0.12 12.2 4.1 0.4 10.4 4.1 2.1 1 1 0 1 1 1 0 Predicted membrane protein (DUF2157) GFO_IDH_MocA PF01408.22 ORY12501.1 - 1.5e-08 35.5 0.1 3.9e-08 34.1 0.1 1.7 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold DHDPS PF00701.22 ORY12503.1 - 9.1e-36 123.0 0.1 1.1e-35 122.7 0.1 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Fungal_trans PF04082.18 ORY12504.1 - 5.5e-25 87.9 0.0 8.1e-25 87.3 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans_2 PF11951.8 ORY12504.1 - 0.016 14.0 0.0 0.024 13.5 0.0 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain GST_N_3 PF13417.6 ORY12505.1 - 3.1e-15 56.3 0.0 5.6e-15 55.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 ORY12505.1 - 5e-14 52.4 0.0 1.3e-13 51.0 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 ORY12505.1 - 4.3e-11 42.9 0.0 9.9e-11 41.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 ORY12505.1 - 5.9e-11 42.5 0.0 1.3e-10 41.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 ORY12505.1 - 8.2e-11 42.0 0.0 1.8e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 ORY12505.1 - 8.5e-07 28.9 0.0 1.5e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glyco_trans_1_2 PF13524.6 ORY12505.1 - 0.17 12.3 0.2 12 6.4 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferases group 1 SF1-HH PF16275.5 ORY12506.1 - 3e-42 143.5 0.1 6.8e-42 142.4 0.1 1.6 1 0 0 1 1 1 1 Splicing factor 1 helix-hairpin domain KH_1 PF00013.29 ORY12506.1 - 5.6e-07 29.3 0.1 1e-06 28.4 0.1 1.5 1 0 0 1 1 1 1 KH domain Myotub-related PF06602.14 ORY12507.1 - 7.7e-147 488.8 0.0 9.3e-147 488.6 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.6 ORY12507.1 - 0.13 12.3 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family Ribosomal_S3_C PF00189.20 ORY12508.1 - 7.9e-25 87.2 0.2 4e-24 84.9 0.1 2.1 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 ORY12508.1 - 6.2e-12 45.2 0.1 1.2e-11 44.3 0.1 1.5 1 0 0 1 1 1 1 KH domain Coilin_N PF15862.5 ORY12508.1 - 0.037 13.8 0.1 0.33 10.7 0.0 2.0 2 0 0 2 2 2 0 Coilin N-terminus UN_NPL4 PF11543.8 ORY12508.1 - 0.11 13.0 0.0 0.2 12.2 0.0 1.4 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Etmic-2 PF06670.11 ORY12508.1 - 1.5 7.7 5.6 2.1 7.2 5.6 1.2 1 0 0 1 1 1 0 Microneme protein Etmic-2 MFS_1 PF07690.16 ORY12509.1 - 7.4e-40 136.9 20.0 7.4e-40 136.9 20.0 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Nuc_sug_transp PF04142.15 ORY12509.1 - 8.7e-09 35.0 0.2 8.7e-09 35.0 0.2 2.1 2 0 0 2 2 2 1 Nucleotide-sugar transporter EamA PF00892.20 ORY12509.1 - 1.2e-06 28.7 22.5 6.3e-05 23.2 10.5 5.2 4 1 0 4 4 4 2 EamA-like transporter family UAA PF08449.11 ORY12509.1 - 8.6e-06 25.2 4.4 8.6e-06 25.2 4.4 3.2 3 1 0 3 3 3 1 UAA transporter family TPT PF03151.16 ORY12509.1 - 0.0024 17.3 0.5 0.0024 17.3 0.5 2.5 2 0 0 2 2 2 1 Triose-phosphate Transporter family DivIC PF04977.15 ORY12512.1 - 0.0012 18.6 3.6 0.054 13.3 0.3 2.3 2 0 0 2 2 2 2 Septum formation initiator ZapB PF06005.12 ORY12512.1 - 0.048 14.1 7.2 0.26 11.8 0.2 2.5 2 0 0 2 2 2 0 Cell division protein ZapB Seryl_tRNA_N PF02403.22 ORY12512.1 - 0.86 9.9 5.8 1.7 8.9 0.6 2.3 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain NPV_P10 PF05531.12 ORY12512.1 - 1.5 9.4 4.3 1.5 9.3 0.8 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Cellulase PF00150.18 ORY12515.1 - 1.8e-09 37.5 0.0 2.7e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) PNRC PF15365.6 ORY12517.1 - 0.52 10.2 2.8 2.8 7.9 0.1 2.7 2 0 0 2 2 2 0 Proline-rich nuclear receptor coactivator motif EBP PF05241.12 ORY12518.1 - 3.2e-06 26.7 0.5 3.2e-06 26.7 0.5 1.5 2 0 0 2 2 2 1 Emopamil binding protein DUF4271 PF14093.6 ORY12518.1 - 0.019 14.9 0.4 0.063 13.2 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4271) Paralemmin PF03285.15 ORY12519.1 - 0.02 14.5 0.5 0.033 13.8 0.5 1.4 1 0 0 1 1 1 0 Paralemmin CytadhesinP1 PF12378.8 ORY12519.1 - 0.19 11.9 0.6 0.7 10.1 0.0 2.2 3 0 0 3 3 3 0 Trypsin-sensitive surface-exposed protein Glyco_hydro_3_C PF01915.22 ORY12520.1 - 3.3e-55 187.2 0.0 4.9e-55 186.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 ORY12520.1 - 2e-32 112.8 0.0 3.9e-32 111.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 ORY12520.1 - 7.9e-17 61.1 0.0 1.8e-16 60.0 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain Forkhead PF00250.18 ORY12521.1 - 1.1e-33 115.4 0.3 1.7e-33 114.7 0.3 1.3 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 ORY12521.1 - 3.3e-07 30.5 0.0 7.1e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 FHA domain Ndufs5 PF10200.9 ORY12522.1 - 0.015 15.5 0.0 0.021 15.0 0.0 1.3 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa DUF3128 PF11326.8 ORY12522.1 - 0.2 12.0 1.2 0.87 10.0 1.2 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) Peptidase_C48 PF02902.19 ORY12523.1 - 3.5e-06 27.0 0.2 4.5e-06 26.7 0.2 1.1 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DUF4097 PF13349.6 ORY12524.1 - 0.0034 16.8 4.9 0.12 11.7 3.8 2.5 1 1 0 1 1 1 1 Putative adhesin HET PF06985.11 ORY12525.1 - 2.7e-13 50.5 0.0 2.7e-13 50.5 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PTS_2-RNA PF01885.16 ORY12526.1 - 2.2e-67 226.6 0.0 2.6e-67 226.4 0.0 1.0 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family Fungal_trans PF04082.18 ORY12527.1 - 4.5e-27 94.7 0.0 8.4e-27 93.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY12527.1 - 2.9e-11 43.3 12.6 4.7e-11 42.6 12.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_L13 PF00572.18 ORY12529.1 - 5.8e-09 36.3 0.0 5.3e-07 29.9 0.0 2.3 1 1 0 1 1 1 1 Ribosomal protein L13 AMP-binding PF00501.28 ORY12530.1 - 6.6e-72 242.4 0.0 8.3e-72 242.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORY12530.1 - 9.5e-17 61.7 0.4 1.9e-16 60.8 0.4 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF3535 PF12054.8 ORY12531.1 - 3.6e-118 395.5 0.0 1.4e-117 393.6 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3535) SNF2_N PF00176.23 ORY12531.1 - 6.1e-65 219.2 0.0 1.4e-64 218.0 0.0 1.5 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ORY12531.1 - 9.8e-21 74.2 0.0 3.4e-20 72.5 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT PF02985.22 ORY12531.1 - 2.2e-12 46.1 14.7 0.065 13.5 0.3 8.5 9 0 0 9 9 8 5 HEAT repeat HEAT_2 PF13646.6 ORY12531.1 - 4.7e-05 23.7 15.1 0.033 14.6 0.0 7.1 8 0 0 8 8 7 2 HEAT repeats Vac14_Fab1_bd PF12755.7 ORY12531.1 - 0.00015 22.3 1.2 1.9 9.1 0.0 4.0 3 1 0 4 4 3 2 Vacuolar 14 Fab1-binding region ResIII PF04851.15 ORY12531.1 - 0.00078 19.5 0.0 0.002 18.2 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CLASP_N PF12348.8 ORY12531.1 - 0.0065 16.1 0.0 0.25 10.9 0.0 2.9 2 0 0 2 2 2 1 CLASP N terminal CshA_NR2 PF18651.1 ORY12531.1 - 0.11 11.7 0.0 0.36 10.0 0.1 1.7 2 0 0 2 2 2 0 Surface adhesin CshA non-repetitive domain 2 CNOT11 PF10155.9 ORY12531.1 - 0.14 12.3 0.0 0.47 10.6 0.0 1.9 1 0 0 1 1 1 0 CCR4-NOT transcription complex subunit 11 UME PF08064.13 ORY12531.1 - 0.37 10.7 6.2 19 5.2 0.0 5.1 7 1 1 8 8 8 0 UME (NUC010) domain IFRD PF05004.13 ORY12531.1 - 0.55 9.3 2.3 11 5.0 0.0 3.7 4 0 0 4 4 4 0 Interferon-related developmental regulator (IFRD) HEAT_EZ PF13513.6 ORY12531.1 - 2.4 8.8 21.3 32 5.2 0.1 8.5 10 0 0 10 10 9 0 HEAT-like repeat Glyco_hydro_47 PF01532.20 ORY12533.1 - 1.6e-139 465.8 0.0 1.8e-139 465.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Cyclin_C PF02984.19 ORY12533.1 - 0.054 13.6 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Cyclin, C-terminal domain Efg1 PF10153.9 ORY12534.1 - 3.1e-33 114.5 9.5 3.1e-33 114.5 9.5 2.5 3 0 0 3 3 3 1 rRNA-processing protein Efg1 zinc_ribbon_16 PF17034.5 ORY12535.1 - 1e-18 67.7 6.1 2.8e-18 66.3 6.1 1.7 1 0 0 1 1 1 1 Zinc-ribbon like family Zn_ribbon_17 PF17120.5 ORY12535.1 - 0.017 14.7 8.2 0.061 13.0 8.2 1.9 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-rbx1 PF12678.7 ORY12535.1 - 0.023 15.0 3.7 0.075 13.3 3.7 1.9 1 0 0 1 1 1 0 RING-H2 zinc finger domain Adaptin_N PF01602.20 ORY12536.1 - 1.8e-143 478.9 0.6 2.3e-143 478.5 0.6 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 ORY12536.1 - 9.2e-23 80.7 0.0 2.4e-22 79.3 0.0 1.7 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 ORY12536.1 - 5.3e-08 33.1 5.3 0.00012 22.1 0.0 3.9 2 2 2 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 ORY12536.1 - 5.6e-05 23.5 1.5 0.62 10.5 0.0 4.3 3 1 0 4 4 4 2 HEAT repeats DUF3730 PF12530.8 ORY12536.1 - 0.00078 19.1 1.0 0.0036 16.9 0.2 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF3730) HEAT PF02985.22 ORY12536.1 - 0.0049 17.0 1.3 20 5.8 0.1 4.1 3 0 0 3 3 3 2 HEAT repeat CLASP_N PF12348.8 ORY12536.1 - 0.03 13.9 0.1 0.55 9.8 0.0 2.5 2 1 0 2 2 2 0 CLASP N terminal MBOAT PF03062.19 ORY12537.1 - 2.1e-27 96.4 18.7 1.5e-26 93.6 18.7 2.0 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 ORY12537.1 - 0.0054 17.0 2.7 0.013 15.7 2.7 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family HET PF06985.11 ORY12538.1 - 1.4e-09 38.4 6.3 5e-07 30.2 0.2 2.8 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) FSH1 PF03959.13 ORY12539.1 - 7.1e-18 65.0 0.0 1.5e-17 64.0 0.0 1.5 1 1 0 1 1 1 1 Serine hydrolase (FSH1) CLIP_1 PF18322.1 ORY12540.1 - 1.1 9.3 16.6 16 5.7 0.4 4.6 4 0 0 4 4 4 0 Serine protease Clip domain PPAF-2 Med25_NR-box PF11244.8 ORY12540.1 - 1.9 8.9 6.1 5.2 7.6 0.5 2.8 1 1 2 3 3 3 0 Mediator complex subunit 25 C-terminal NR box-containing BAG PF02179.16 ORY12541.1 - 3.1e-20 72.4 1.4 5.8e-20 71.5 0.2 2.2 2 0 0 2 2 2 1 BAG domain CorA PF01544.18 ORY12543.1 - 0.00051 19.4 8.6 0.003 16.9 7.0 2.3 1 1 1 2 2 2 2 CorA-like Mg2+ transporter protein Saf_2TM PF18303.1 ORY12543.1 - 0.031 13.9 0.5 0.062 12.9 0.5 1.5 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain Pkinase PF00069.25 ORY12544.1 - 9.1e-17 61.3 0.0 3.4e-16 59.4 0.0 2.0 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY12544.1 - 0.036 13.4 0.0 0.075 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein tyrosine kinase zf-C2H2 PF00096.26 ORY12546.1 - 1.1e-06 28.7 18.2 3.2e-05 24.2 2.8 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY12546.1 - 2.5e-05 24.5 3.3 2.5e-05 24.5 3.3 2.8 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORY12546.1 - 0.0001 22.8 1.7 0.0001 22.8 1.7 3.4 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_6 PF13912.6 ORY12546.1 - 0.0032 17.4 1.3 0.0077 16.2 1.3 1.6 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORY12546.1 - 0.0036 17.6 0.7 0.0036 17.6 0.7 1.8 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 ORY12546.1 - 0.03 14.6 3.8 0.26 11.6 3.3 2.4 1 1 1 2 2 2 0 C2H2-type zinc ribbon FOXP-CC PF16159.5 ORY12546.1 - 0.03 14.9 10.1 0.4 11.3 2.2 3.4 1 1 2 3 3 3 0 FOXP coiled-coil domain zf-TRAF PF02176.18 ORY12546.1 - 2.4 8.9 8.0 0.33 11.7 2.6 2.1 1 1 1 2 2 2 0 TRAF-type zinc finger DUF3602 PF12223.8 ORY12547.1 - 2.4e-13 50.5 9.5 1.8e-06 28.4 4.0 3.2 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) GTP1_OBG PF01018.22 ORY12547.1 - 0.019 14.6 4.0 0.15 11.6 0.1 2.9 2 1 1 3 3 3 0 GTP1/OBG Ferric_reduct PF01794.19 ORY12548.1 - 4.3e-20 72.1 4.9 4.3e-20 72.1 4.9 2.3 2 1 1 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 ORY12548.1 - 1.7e-15 57.4 0.0 2.5e-15 56.9 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 ORY12548.1 - 1.2e-14 54.3 0.0 2.7e-14 53.1 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 ORY12548.1 - 0.021 15.5 0.0 5.9 7.6 0.0 2.3 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain IU_nuc_hydro PF01156.19 ORY12549.1 - 3.5e-76 256.7 0.0 4.2e-76 256.4 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Glyco_hydro_10 PF00331.20 ORY12550.1 - 3.2e-93 312.3 0.1 3.7e-93 312.2 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Ribosomal_L7Ae PF01248.26 ORY12552.1 - 2.4e-25 88.1 0.9 4.8e-25 87.1 0.9 1.5 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family LRR_6 PF13516.6 ORY12553.1 - 6.1e-15 53.9 25.2 0.57 10.4 0.0 12.2 13 0 0 13 13 13 6 Leucine Rich repeat LRR_4 PF12799.7 ORY12553.1 - 5e-14 52.2 7.9 0.12 12.9 0.0 6.9 5 1 2 7 7 7 6 Leucine Rich repeats (2 copies) F-box-like PF12937.7 ORY12553.1 - 9.9e-10 38.2 0.2 1.4e-08 34.5 0.0 2.5 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 ORY12553.1 - 0.00086 19.1 0.6 0.028 14.3 0.4 3.0 2 0 0 2 2 2 1 F-box domain DUF1699 PF08004.11 ORY12553.1 - 0.0058 16.3 0.0 1.2 8.8 0.0 3.2 3 1 0 3 3 3 1 Protein of unknown function (DUF1699) SAM_Ste50p PF09235.10 ORY12553.1 - 0.88 9.9 21.8 36 4.7 0.1 8.6 4 3 6 10 10 10 0 Ste50p, sterile alpha motif LRR_1 PF00560.33 ORY12553.1 - 8.6 7.3 20.5 27 5.8 0.1 8.1 9 1 0 9 9 9 0 Leucine Rich Repeat Pkinase PF00069.25 ORY12554.1 - 1.3e-40 139.4 0.0 2e-40 138.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY12554.1 - 2.5e-31 108.9 0.0 3.5e-31 108.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY12554.1 - 0.018 14.4 0.0 0.031 13.6 0.0 1.3 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 ORY12554.1 - 0.093 12.6 0.6 14 5.5 0.0 2.8 3 1 1 4 4 4 0 Phosphotransferase enzyme family Spt5_N PF11942.8 ORY12554.1 - 8.8 7.4 9.0 5.8 8.0 3.6 2.5 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Collar PF07484.12 ORY12555.1 - 2.7e-05 24.1 2.8 0.032 14.2 0.1 3.7 2 2 1 3 3 3 3 Phage Tail Collar Domain DUF3433 PF11915.8 ORY12582.1 - 1.3e-12 48.0 1.8 1.3e-12 48.0 1.8 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF3433) PRD1_DD PF11087.8 ORY12582.1 - 0.032 13.9 1.2 0.1 12.3 1.2 1.8 1 0 0 1 1 1 0 PRD1 phage membrane DNA delivery Pyr_redox_2 PF07992.14 ORY12583.1 - 5.2e-18 65.3 0.0 1.2e-17 64.1 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ORY12583.1 - 2.7e-07 29.7 0.0 0.0001 21.2 0.0 2.5 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_3 PF13738.6 ORY12583.1 - 6.5e-07 28.9 0.0 0.016 14.5 0.0 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ORY12583.1 - 2e-06 27.2 0.3 6.5e-05 22.2 0.0 2.5 3 0 0 3 3 3 1 FAD binding domain GIDA PF01134.22 ORY12583.1 - 3.4e-06 26.4 0.1 0.00084 18.5 0.1 2.4 1 1 1 2 2 2 2 Glucose inhibited division protein A NAD_binding_9 PF13454.6 ORY12583.1 - 2.2e-05 24.5 0.5 0.12 12.3 0.0 2.5 3 0 0 3 3 2 2 FAD-NAD(P)-binding DAO PF01266.24 ORY12583.1 - 3.1e-05 23.7 0.9 0.047 13.3 0.5 2.4 1 1 1 2 2 2 2 FAD dependent oxidoreductase FAD_oxidored PF12831.7 ORY12583.1 - 0.00013 21.5 0.1 0.00022 20.7 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ORY12583.1 - 0.00018 21.6 0.0 0.00059 20.0 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 ORY12583.1 - 0.00063 19.1 0.0 0.0017 17.7 0.0 1.6 2 0 0 2 2 2 1 Thi4 family K_oxygenase PF13434.6 ORY12583.1 - 0.014 14.6 0.0 2.6 7.1 0.0 2.2 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.12 ORY12583.1 - 0.016 14.3 0.0 0.025 13.7 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_3 PF01494.19 ORY12583.1 - 0.023 13.9 0.0 0.045 13.0 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain YscJ_FliF PF01514.17 ORY12583.1 - 0.05 13.3 0.1 0.072 12.7 0.1 1.3 1 0 0 1 1 1 0 Secretory protein of YscJ/FliF family AlaDh_PNT_C PF01262.21 ORY12583.1 - 0.12 11.6 0.1 0.95 8.7 0.0 2.3 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain DUF2633 PF11119.8 ORY12584.1 - 0.0029 17.5 0.5 0.014 15.3 0.5 2.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2633) DUF2871 PF11070.8 ORY12584.1 - 0.016 15.5 0.7 0.031 14.5 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2871) CbiM PF01891.16 ORY12584.1 - 0.68 9.7 5.5 0.18 11.6 1.9 1.9 2 1 0 2 2 2 0 Cobalt uptake substrate-specific transmembrane region RCR PF12273.8 ORY12584.1 - 4.2 8.1 5.3 19 5.9 2.3 2.2 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red NSP10 PF09401.10 ORY12586.1 - 0.0051 16.9 0.2 0.0069 16.4 0.2 1.2 1 0 0 1 1 1 1 RNA synthesis protein NSP10 ABC_membrane PF00664.23 ORY12587.1 - 6.1e-44 150.7 11.9 7.6e-44 150.4 11.9 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 ORY12587.1 - 4.2e-34 118.0 0.0 7.5e-34 117.2 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 ORY12587.1 - 1.7e-05 24.3 0.1 0.016 14.7 0.0 2.3 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 ORY12587.1 - 0.00045 20.5 0.4 0.0058 16.9 0.0 2.6 3 0 0 3 3 2 1 AAA domain AAA_21 PF13304.6 ORY12587.1 - 0.00099 19.0 0.1 0.02 14.7 0.0 2.3 1 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 ORY12587.1 - 0.0011 19.4 0.1 0.0032 17.9 0.0 1.9 2 1 0 2 2 1 1 AAA ATPase domain AAA_14 PF13173.6 ORY12587.1 - 0.01 15.9 0.0 0.12 12.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 ORY12587.1 - 0.013 15.2 0.0 0.021 14.5 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain MMR_HSR1 PF01926.23 ORY12587.1 - 0.015 15.3 0.0 0.2 11.8 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_29 PF13555.6 ORY12587.1 - 0.017 14.8 0.1 0.047 13.4 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Rad17 PF03215.15 ORY12587.1 - 0.018 14.9 0.0 0.041 13.8 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_24 PF13479.6 ORY12587.1 - 0.021 14.5 0.0 0.046 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 ORY12587.1 - 0.031 14.7 0.0 0.24 11.8 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 ORY12587.1 - 0.031 14.8 0.1 0.065 13.7 0.1 1.4 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 ORY12587.1 - 0.033 14.1 0.0 0.08 12.8 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_18 PF13238.6 ORY12587.1 - 0.033 14.7 0.0 0.079 13.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 ORY12587.1 - 0.038 14.2 0.0 0.12 12.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 ORY12587.1 - 0.043 13.4 0.0 0.11 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 ORY12587.1 - 0.06 13.1 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 Cytidylate kinase TPR_1 PF00515.28 ORY12587.1 - 0.096 12.6 0.4 0.35 10.8 0.3 2.0 1 1 0 1 1 1 0 Tetratricopeptide repeat ATP-synt_ab PF00006.25 ORY12587.1 - 0.1 12.2 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain TPR_11 PF13414.6 ORY12587.1 - 0.17 11.6 0.5 0.41 10.4 0.5 1.6 1 0 0 1 1 1 0 TPR repeat TPR_7 PF13176.6 ORY12587.1 - 0.19 11.8 0.5 3 8.1 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat AIM24 PF01987.17 ORY12588.1 - 9.5e-52 175.7 0.1 1.2e-51 175.4 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 Oxygenase-NA PF09859.9 ORY12589.1 - 0.047 13.2 1.6 0.067 12.7 1.6 1.3 1 0 0 1 1 1 0 Oxygenase, catalysing oxidative methylation of damaged DNA HET PF06985.11 ORY12590.1 - 3.3e-34 118.3 8.5 1.3e-32 113.1 8.5 2.0 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) 2OG-FeII_Oxy_2 PF13532.6 ORY12592.1 - 2.7e-37 128.9 0.0 3.9e-37 128.3 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-GRF PF06839.12 ORY12592.1 - 5.6e-05 23.1 7.4 0.00011 22.2 7.4 1.5 1 0 0 1 1 1 1 GRF zinc finger Ead_Ea22 PF13935.6 ORY12592.1 - 0.068 13.8 0.0 0.13 12.9 0.0 1.6 1 0 0 1 1 1 0 Ead/Ea22-like protein WD40 PF00400.32 ORY12593.1 - 2.3e-14 53.5 16.6 0.0037 18.1 0.3 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat DUF4280 PF14107.6 ORY12593.1 - 0.17 12.7 0.0 0.5 11.2 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4280) Abhydrolase_3 PF07859.13 ORY12594.1 - 2.3e-30 106.0 0.0 3.1e-30 105.6 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 ORY12594.1 - 0.0016 17.4 0.0 0.0055 15.6 0.0 1.8 1 1 0 1 1 1 1 Carboxylesterase family Thioesterase PF00975.20 ORY12594.1 - 0.006 16.7 0.0 0.0091 16.1 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain DUF2974 PF11187.8 ORY12594.1 - 0.15 11.6 0.1 0.25 10.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Peptidase_S10 PF00450.22 ORY12595.1 - 4e-69 234.0 0.0 5.5e-69 233.6 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Peptidase_S10 PF00450.22 ORY12596.1 - 4.8e-47 161.3 0.0 1.4e-46 159.8 0.0 1.6 1 1 0 1 1 1 1 Serine carboxypeptidase Peptidase_S10 PF00450.22 ORY12597.1 - 2.9e-46 158.7 0.1 3.7e-46 158.4 0.1 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Peptidase_S10 PF00450.22 ORY12598.1 - 2.4e-72 244.7 0.1 3.4e-72 244.2 0.1 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase CNOT1_HEAT_N PF16419.5 ORY12599.1 - 0.14 11.8 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 CCR4-NOT transcription complex subunit 1 HEAT repeat Claudin_2 PF13903.6 ORY12600.1 - 0.033 14.0 0.2 0.033 14.0 0.2 2.6 2 1 1 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction DUF1616 PF07760.11 ORY12600.1 - 0.058 12.8 0.2 0.26 10.6 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1616) DRIM PF07539.12 ORY12603.1 - 6.9e-189 629.2 6.2 6.9e-189 629.2 6.2 3.5 4 0 0 4 4 4 1 Down-regulated in metastasis HEAT_2 PF13646.6 ORY12603.1 - 0.0058 17.0 9.6 2.3 8.7 0.2 6.7 7 0 0 7 7 7 2 HEAT repeats Arm PF00514.23 ORY12603.1 - 0.012 15.6 0.7 0.49 10.5 0.3 3.8 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat DUF1722 PF08349.11 ORY12603.1 - 0.078 13.3 1.6 23 5.3 0.0 4.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1722) SHQ1 PF04925.15 ORY12603.1 - 0.12 11.9 0.1 1.2 8.6 0.0 2.4 2 0 0 2 2 2 0 SHQ1 protein Ecm29 PF13001.7 ORY12603.1 - 0.46 9.1 4.6 1.7 7.3 0.1 3.9 5 0 0 5 5 5 0 Proteasome stabiliser Utp12 PF04003.12 ORY12603.1 - 1.5 9.1 4.6 7.7 6.9 0.3 4.5 3 0 0 3 3 3 0 Dip2/Utp12 Family CwfJ_C_1 PF04677.15 ORY12604.1 - 1.5e-21 76.5 0.0 2.4e-21 75.9 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 ORY12604.1 - 5.3e-14 52.9 1.0 1.1e-13 51.9 1.0 1.5 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 HIT PF01230.23 ORY12604.1 - 0.045 14.5 0.0 0.11 13.3 0.0 1.6 1 0 0 1 1 1 0 HIT domain DUF1524 PF07510.11 ORY12605.1 - 3.1e-09 36.8 0.0 3.7e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1524) HNH_4 PF13395.6 ORY12605.1 - 0.11 12.5 0.3 0.4 10.6 0.3 1.9 1 1 0 1 1 1 0 HNH endonuclease Shisa PF13908.6 ORY12606.1 - 0.00056 20.2 3.4 0.00056 20.2 3.4 2.5 1 1 1 2 2 2 1 Wnt and FGF inhibitory regulator Mid2 PF04478.12 ORY12606.1 - 0.003 17.4 0.0 0.0058 16.5 0.0 1.5 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Podoplanin PF05808.11 ORY12606.1 - 0.0034 17.5 0.3 0.0054 16.9 0.3 1.3 1 0 0 1 1 1 1 Podoplanin CYYR1 PF10873.8 ORY12606.1 - 0.0075 16.7 2.2 0.0075 16.7 2.2 3.6 2 2 3 5 5 5 1 Cysteine and tyrosine-rich protein 1 ECF_trnsprt PF12822.7 ORY12606.1 - 0.039 14.1 0.1 0.063 13.4 0.1 1.2 1 0 0 1 1 1 0 ECF transporter, substrate-specific component PepSY_TM PF03929.16 ORY12606.1 - 0.53 9.9 3.7 0.71 9.5 2.5 1.7 1 1 0 1 1 1 0 PepSY-associated TM region DSBA PF01323.20 ORY12607.1 - 8.1e-34 117.1 0.0 9.5e-34 116.9 0.0 1.1 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 ORY12607.1 - 0.00071 19.8 0.1 0.0029 17.8 0.0 1.9 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_5 PF13743.6 ORY12607.1 - 0.033 13.9 0.0 0.07 12.8 0.0 1.5 2 0 0 2 2 2 0 Thioredoxin Thioredoxin_3 PF13192.6 ORY12607.1 - 0.082 13.0 0.2 3.5 7.8 0.0 2.5 2 1 0 2 2 2 0 Thioredoxin domain Myb_DNA-bind_3 PF12776.7 ORY12608.1 - 3.5e-09 37.5 0.1 5.2e-09 37.0 0.1 1.2 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 ORY12608.1 - 0.023 15.0 0.1 0.039 14.3 0.1 1.3 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Ribosomal_S18 PF01084.20 ORY12609.1 - 2.4e-14 53.3 0.0 4.3e-14 52.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S18 PPR_2 PF13041.6 ORY12610.1 - 2.8e-14 53.0 0.2 0.0014 18.8 0.0 7.7 7 1 1 8 8 8 4 PPR repeat family PPR_3 PF13812.6 ORY12610.1 - 8.2e-09 35.4 0.1 0.011 15.8 0.0 5.8 5 1 0 5 5 5 1 Pentatricopeptide repeat domain PPR PF01535.20 ORY12610.1 - 1.7e-07 31.0 4.3 1.9 8.9 0.0 7.0 7 0 0 7 7 7 2 PPR repeat TPR_14 PF13428.6 ORY12610.1 - 0.0084 16.8 0.0 73 4.6 0.0 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat BTAD PF03704.17 ORY12610.1 - 0.057 13.9 0.0 4.9 7.6 0.0 2.8 3 0 0 3 3 3 0 Bacterial transcriptional activator domain Glyco_hydro_25 PF01183.20 ORY12610.1 - 0.12 12.6 0.3 0.33 11.1 0.3 1.7 1 0 0 1 1 1 0 Glycosyl hydrolases family 25 TPR_4 PF07721.14 ORY12610.1 - 0.56 11.0 2.5 40 5.3 0.0 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat CbiG_mid PF11761.8 ORY12611.1 - 0.22 11.6 0.4 14 5.9 0.0 2.4 2 0 0 2 2 2 0 Cobalamin biosynthesis central region Kelch_5 PF13854.6 ORY12612.1 - 7e-22 77.0 8.4 9.1e-10 38.3 0.1 4.2 4 0 0 4 4 4 3 Kelch motif Kelch_4 PF13418.6 ORY12612.1 - 1.3e-13 50.7 6.4 0.0091 16.0 0.0 5.8 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_6 PF13964.6 ORY12612.1 - 5e-13 48.8 7.7 0.0012 19.1 0.2 4.9 5 0 0 5 5 5 3 Kelch motif Kelch_3 PF13415.6 ORY12612.1 - 2e-09 37.5 7.5 0.27 11.6 0.0 5.6 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_1 PF01344.25 ORY12612.1 - 5.5e-08 32.3 4.5 0.0085 15.7 0.4 4.5 4 0 0 4 4 4 3 Kelch motif Kelch_2 PF07646.15 ORY12612.1 - 3.9e-05 23.5 6.0 0.077 13.0 0.3 3.9 5 0 0 5 5 5 2 Kelch motif Tmemb_14 PF03647.13 ORY12612.1 - 0.46 11.3 2.1 37 5.2 0.0 3.0 3 0 0 3 3 3 0 Transmembrane proteins 14C Insulin_TMD PF17870.1 ORY12614.1 - 0.088 12.9 0.9 0.16 12.0 0.9 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Hce2 PF14856.6 ORY12617.1 - 1.7e-22 79.6 0.1 2.1e-22 79.3 0.1 1.1 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor Hce2 PF14856.6 ORY12618.1 - 9.5e-17 61.2 0.5 1.2e-16 60.8 0.5 1.1 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor DUF5012 PF16404.5 ORY12618.1 - 0.047 13.8 0.0 0.064 13.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5012) Big_3_3 PF13750.6 ORY12620.1 - 0.00014 21.5 0.1 0.00035 20.2 0.0 1.6 2 0 0 2 2 2 1 Bacterial Ig-like domain (group 3) Astacin PF01400.24 ORY12621.1 - 0.0047 16.6 1.4 0.047 13.3 0.4 2.2 1 1 1 2 2 2 2 Astacin (Peptidase family M12A) Zn_clus PF00172.18 ORY12623.1 - 2e-08 34.2 10.4 3.3e-08 33.5 10.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3491 PF11996.8 ORY12623.1 - 0.13 10.0 0.0 0.18 9.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3491) zf-DNL PF05180.12 ORY12624.1 - 3.5e-30 103.7 2.5 4.9e-30 103.3 2.5 1.2 1 0 0 1 1 1 1 DNL zinc finger zinc_ribbon_4 PF13717.6 ORY12624.1 - 0.0007 19.5 0.7 0.77 9.7 0.1 2.5 2 0 0 2 2 2 2 zinc-ribbon domain Elf1 PF05129.13 ORY12624.1 - 0.01 15.8 0.4 0.019 15.0 0.4 1.4 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like HypA PF01155.19 ORY12624.1 - 0.088 12.8 0.1 0.13 12.3 0.1 1.3 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn-ribbon_8 PF09723.10 ORY12624.1 - 0.18 12.0 0.8 0.36 11.0 0.8 1.5 1 0 0 1 1 1 0 Zinc ribbon domain Zn_Tnp_IS1595 PF12760.7 ORY12624.1 - 4.1 7.5 5.6 24 5.0 0.5 2.3 1 1 1 2 2 2 0 Transposase zinc-ribbon domain Cullin PF00888.22 ORY12625.1 - 1.4e-208 694.5 3.3 2e-208 694.0 3.3 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 ORY12625.1 - 6.7e-26 90.1 2.1 1.3e-24 86.0 0.5 3.4 3 0 0 3 3 3 1 Cullin protein neddylation domain HTH_IclR PF09339.10 ORY12625.1 - 0.19 11.6 0.0 0.49 10.2 0.0 1.7 1 0 0 1 1 1 0 IclR helix-turn-helix domain Glyco_hydro_cc PF11790.8 ORY12628.1 - 1.5e-56 191.7 0.2 1.9e-56 191.3 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Cellulase PF00150.18 ORY12628.1 - 0.004 16.6 0.3 0.0068 15.9 0.3 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) NACHT PF05729.12 ORY12629.1 - 0.00034 20.6 0.8 0.012 15.5 0.1 2.9 2 1 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 ORY12629.1 - 0.0079 16.5 0.6 0.21 11.8 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 ORY12629.1 - 0.013 16.0 0.5 0.038 14.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain Ank_4 PF13637.6 ORY12629.1 - 0.016 15.8 0.0 5.3 7.7 0.0 3.9 4 0 0 4 4 4 0 Ankyrin repeats (many copies) AAA_29 PF13555.6 ORY12629.1 - 0.055 13.2 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 ORY12629.1 - 0.083 13.3 5.9 1.1 9.6 0.0 3.8 3 1 0 3 3 3 0 AAA ATPase domain RNA_helicase PF00910.22 ORY12629.1 - 0.099 13.0 0.1 0.25 11.8 0.1 1.7 1 0 0 1 1 1 0 RNA helicase SesA PF17107.5 ORY12629.1 - 0.12 12.6 1.0 0.34 11.1 0.1 2.1 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases ABC_tran PF00005.27 ORY12629.1 - 0.12 12.9 0.2 0.48 10.9 0.0 2.1 2 0 0 2 2 2 0 ABC transporter HalX PF08663.10 ORY12629.1 - 0.54 10.6 3.9 3.9 7.9 0.3 3.4 3 0 0 3 3 3 0 HalX domain DUF2802 PF10975.8 ORY12629.1 - 0.79 9.9 4.4 17 5.6 0.0 3.9 5 0 0 5 5 5 0 Protein of unknown function (DUF2802) DUF1996 PF09362.10 ORY12630.1 - 9.8e-83 277.7 1.6 1.3e-82 277.3 1.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) WSC PF01822.19 ORY12630.1 - 3.5e-19 68.8 11.6 3.5e-19 68.8 11.6 2.3 2 0 0 2 2 2 1 WSC domain DJ-1_PfpI PF01965.24 ORY12631.1 - 0.0016 18.3 0.0 0.0023 17.7 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family Ctr PF04145.15 ORY12632.1 - 3.8e-44 150.9 1.2 4.4e-44 150.7 1.2 1.0 1 0 0 1 1 1 1 Ctr copper transporter family DUF2244 PF10003.9 ORY12632.1 - 0.26 11.0 1.6 1.8 8.2 1.0 2.0 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) Sensor PF13796.6 ORY12632.1 - 0.32 11.0 4.1 9.1 6.3 1.2 2.2 1 1 1 2 2 2 0 Putative sensor LapA_dom PF06305.11 ORY12632.1 - 0.4 10.5 0.2 0.4 10.5 0.2 2.2 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain CFEM PF05730.11 ORY12633.1 - 0.003 17.6 5.4 0.0059 16.7 5.4 1.4 1 0 0 1 1 1 1 CFEM domain HET PF06985.11 ORY12635.1 - 2.2e-08 34.6 0.0 2.7e-08 34.3 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF3047 PF11249.8 ORY12635.1 - 0.093 12.2 0.0 0.097 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3047) DUF3176 PF11374.8 ORY12636.1 - 5.4e-19 68.4 1.0 1.2e-18 67.2 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) Exosortase_EpsH PF09721.10 ORY12636.1 - 4 6.9 6.7 3.3 7.2 1.3 2.2 2 0 0 2 2 2 0 Transmembrane exosortase (Exosortase_EpsH) DUF1996 PF09362.10 ORY12639.1 - 2.9e-82 276.2 0.5 3.6e-82 275.9 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Ricin_B_lectin PF00652.22 ORY12640.1 - 9.5e-12 45.3 2.8 5.5e-08 33.1 0.1 2.0 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 ORY12640.1 - 1.1e-07 32.4 0.4 0.00023 21.8 0.0 2.1 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like MBOAT PF03062.19 ORY12642.1 - 4.9e-44 151.1 17.8 1.6e-43 149.4 12.0 2.5 2 1 0 2 2 2 2 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 ORY12642.1 - 9e-05 22.7 3.9 0.00026 21.2 3.9 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family DUF2612 PF11041.8 ORY12642.1 - 0.11 12.4 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2612) zf-MYND PF01753.18 ORY12644.1 - 7.9e-12 45.1 17.1 1.3e-11 44.3 17.1 1.4 1 0 0 1 1 1 1 MYND finger Ecl1 PF12855.7 ORY12644.1 - 0.0043 18.2 6.4 0.0065 17.7 6.4 1.4 1 0 0 1 1 1 1 ECL1/2/3 zinc binding proteins zf-C6H2 PF15801.5 ORY12644.1 - 0.032 14.5 12.0 0.073 13.4 12.0 1.6 1 1 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Rhodanese_C PF12368.8 ORY12644.1 - 1.1 9.7 10.2 2.2 8.7 10.2 1.5 1 0 0 1 1 1 0 Rhodanase C-terminal Mito_carr PF00153.27 ORY12645.1 - 2.7e-57 190.7 6.0 2.2e-19 69.2 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein AhpC-TSA PF00578.21 ORY12646.1 - 2e-29 102.0 0.0 2.7e-29 101.6 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.9 ORY12646.1 - 8.1e-15 54.4 0.1 1.5e-14 53.5 0.1 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.10 ORY12646.1 - 3e-13 49.7 0.0 3.9e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 Redoxin Pmp3 PF01679.17 ORY12648.1 - 0.021 15.0 2.7 0.037 14.2 2.7 1.4 1 0 0 1 1 1 0 Proteolipid membrane potential modulator DUF1179 PF06678.11 ORY12648.1 - 2.5 8.1 7.1 0.34 10.9 2.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1179) Myb_DNA-binding PF00249.31 ORY12650.1 - 9.8e-20 70.5 9.0 1.4e-13 50.8 0.6 3.9 4 0 0 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORY12650.1 - 2.1e-14 53.5 7.4 5.3e-11 42.6 4.6 2.8 2 0 0 2 2 2 2 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 ORY12650.1 - 0.0042 17.2 0.2 0.0042 17.2 0.2 2.4 2 1 1 3 3 3 1 SANT/Myb-like domain of DAMP1 Rap1_C PF11626.8 ORY12650.1 - 0.14 12.3 0.7 0.58 10.3 0.7 2.1 1 0 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain SnoaL PF07366.12 ORY12651.1 - 3.2e-07 30.2 0.1 5.1e-07 29.5 0.1 1.3 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 ORY12651.1 - 1.2e-05 25.9 0.2 2.2e-05 25.0 0.2 1.4 1 0 0 1 1 1 1 SnoaL-like domain DLH PF01738.18 ORY12651.1 - 0.17 11.4 0.0 0.46 10.0 0.0 1.7 1 1 0 1 1 1 0 Dienelactone hydrolase family Ank_4 PF13637.6 ORY12652.1 - 1e-05 25.9 0.1 0.022 15.4 0.1 2.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 ORY12652.1 - 0.0028 18.2 0.1 0.091 13.4 0.1 2.3 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 ORY12652.1 - 0.11 13.0 0.3 1.5 9.4 0.0 2.6 2 0 0 2 2 2 0 Ankyrin repeat Spt5_N PF11942.8 ORY12652.1 - 5 8.2 9.0 0.95 10.5 3.4 2.2 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Ank_2 PF12796.7 ORY12653.1 - 2.6e-15 56.7 0.6 1.4e-06 28.8 0.2 2.9 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY12653.1 - 7.4e-12 45.5 1.2 0.0056 17.2 0.0 3.6 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY12653.1 - 2.7e-11 42.6 1.4 0.0077 16.7 0.0 5.2 5 1 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 ORY12653.1 - 2.8e-11 43.4 3.3 0.00037 20.7 0.1 4.4 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 ORY12653.1 - 1.7e-07 31.4 5.3 0.013 16.0 0.0 5.1 5 1 0 5 5 5 2 Ankyrin repeat SH3_9 PF14604.6 ORY12654.1 - 8.9e-10 38.3 0.0 1.3e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 ORY12654.1 - 6.6e-06 25.6 0.0 9.8e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 ORY12654.1 - 7.1e-06 25.6 0.0 1.1e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain Podoplanin PF05808.11 ORY12654.1 - 0.039 14.1 6.4 0.095 12.8 6.4 1.7 1 1 0 1 1 1 0 Podoplanin Nitrate_red_gam PF02665.14 ORY12654.1 - 0.066 12.7 0.1 0.1 12.1 0.1 1.2 1 0 0 1 1 1 0 Nitrate reductase gamma subunit DUF5431 PF17496.2 ORY12655.1 - 0.12 12.5 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5431) CBM_4_9 PF02018.17 ORY12656.1 - 3.1e-11 43.7 6.8 0.0059 16.9 0.0 4.6 5 0 0 5 5 5 3 Carbohydrate binding domain DUF4596 PF15363.6 ORY12656.1 - 0.048 13.9 1.2 0.23 11.7 1.2 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4596) Phospholip_A2_3 PF09056.11 ORY12657.1 - 4.3e-45 152.9 3.7 5e-45 152.7 3.7 1.0 1 0 0 1 1 1 1 Prokaryotic phospholipase A2 PLA2G12 PF06951.11 ORY12657.1 - 0.0015 18.5 0.1 0.0019 18.1 0.1 1.2 1 0 0 1 1 1 1 Group XII secretory phospholipase A2 precursor (PLA2G12) BTB PF00651.31 ORY12658.1 - 0.07 13.4 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 BTB/POZ domain Med4 PF10018.9 ORY12659.1 - 6.4e-36 123.9 10.0 2e-35 122.2 10.0 1.8 1 1 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 DUF4407 PF14362.6 ORY12659.1 - 0.95 8.8 5.2 1.8 7.8 1.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF1682 PF07946.14 ORY12659.1 - 8.7 5.4 11.7 17 4.5 11.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) EF-hand_7 PF13499.6 ORY12660.1 - 1.1e-24 86.7 7.3 5e-16 58.9 0.5 3.1 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 ORY12660.1 - 1.4e-24 83.8 12.6 3e-08 32.7 0.1 5.0 5 1 1 6 6 6 3 EF hand EF-hand_6 PF13405.6 ORY12660.1 - 7.3e-24 81.6 5.8 2.6e-06 26.9 0.1 5.4 4 1 2 6 6 6 4 EF-hand domain EF-hand_5 PF13202.6 ORY12660.1 - 2.2e-17 61.7 14.2 2e-05 23.8 0.0 4.9 6 0 0 6 6 6 4 EF hand EF-hand_8 PF13833.6 ORY12660.1 - 3.5e-15 55.6 10.3 1.5e-05 24.7 0.8 3.9 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.7 ORY12660.1 - 6.9e-09 35.6 6.7 0.0017 18.3 0.1 4.0 1 1 3 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 ORY12660.1 - 0.0003 21.0 0.4 0.012 15.9 0.1 3.0 2 1 1 3 3 3 1 EF-hand domain SPARC_Ca_bdg PF10591.9 ORY12660.1 - 0.00037 20.8 3.3 0.61 10.4 0.2 3.4 2 2 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region DUF1679 PF07914.11 ORY12660.1 - 0.024 13.5 0.2 1.3 7.8 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) EF-hand_14 PF17959.1 ORY12660.1 - 0.25 11.7 1.6 9.8 6.6 0.0 3.4 4 0 0 4 4 4 0 EF-hand domain EF-hand_10 PF14788.6 ORY12660.1 - 0.76 9.7 8.2 0.97 9.3 0.0 4.2 4 1 1 5 5 5 0 EF hand EMP70 PF02990.16 ORY12661.1 - 1.1e-202 674.4 3.9 1.6e-202 673.8 3.9 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 DUF4190 PF13828.6 ORY12662.1 - 0.23 11.3 2.3 0.38 10.5 2.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4190) Abhydrolase_4 PF08386.10 ORY12663.1 - 3.8e-17 62.3 0.0 8.5e-17 61.2 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.20 ORY12663.1 - 5.6e-09 36.0 0.1 6.3e-05 22.7 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Lgl_C PF08596.10 ORY12680.1 - 1.2e-124 416.0 0.0 2.1e-124 415.2 0.0 1.4 1 0 0 1 1 1 1 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.32 ORY12680.1 - 3.6e-07 30.8 0.1 0.0049 17.7 0.0 4.1 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY12680.1 - 7.7e-07 29.3 0.0 0.014 15.6 0.0 5.4 4 2 2 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain AMMECR1 PF01871.17 ORY12683.1 - 2.2e-46 157.5 0.0 4.9e-46 156.4 0.0 1.5 2 0 0 2 2 2 1 AMMECR1 DUF4236 PF14020.6 ORY12683.1 - 0.093 13.3 0.1 0.093 13.3 0.1 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF4236) Ribosomal_L29e PF01779.17 ORY12684.1 - 3.1e-19 69.0 13.9 8.8e-19 67.5 11.8 2.1 2 0 0 2 2 2 1 Ribosomal L29e protein family Glyco_hydro2_C5 PF18565.1 ORY12684.1 - 0.065 13.1 0.0 0.098 12.5 0.0 1.4 1 0 0 1 1 1 0 Glycoside hydrolase family 2 C-terminal domain 5 zf-Di19 PF05605.12 ORY12687.1 - 0.063 13.6 8.2 1.8 9.0 0.9 2.9 2 1 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding Asp_protease_2 PF13650.6 ORY12690.1 - 0.056 14.1 0.0 0.14 12.8 0.0 1.8 1 0 0 1 1 1 0 Aspartyl protease HTH_31 PF13560.6 ORY12690.1 - 0.11 12.8 0.1 1.6 9.2 0.1 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain gag-asp_proteas PF13975.6 ORY12690.1 - 0.14 12.7 0.0 0.3 11.7 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Nop14 PF04147.12 ORY12691.1 - 0.0014 16.9 8.0 0.0014 16.9 8.0 1.7 2 0 0 2 2 2 1 Nop14-like family Arteri_nucleo PF01481.16 ORY12691.1 - 0.077 13.3 0.0 0.17 12.2 0.0 1.6 1 0 0 1 1 1 0 Arterivirus nucleocapsid protein MFS_1 PF07690.16 ORY12692.1 - 7.8e-33 113.9 33.6 7.6e-32 110.6 35.5 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily JAB PF01398.21 ORY12693.1 - 5.6e-16 58.6 0.0 1.9e-15 56.9 0.0 1.8 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease USP8_dimer PF08969.11 ORY12693.1 - 2e-06 28.0 0.0 3.7e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 USP8 dimerisation domain Prok-JAB PF14464.6 ORY12693.1 - 6.8e-05 22.6 0.0 0.00017 21.3 0.0 1.6 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Pkr1 PF08636.10 ORY12694.1 - 1.6e-29 101.9 6.9 2.1e-29 101.5 6.9 1.1 1 0 0 1 1 1 1 ER protein Pkr1 Phage_Gp23 PF10669.9 ORY12694.1 - 0.23 11.8 2.4 0.58 10.5 2.4 1.6 1 1 0 1 1 1 0 Protein gp23 (Bacteriophage A118) Complex1_LYR_2 PF13233.6 ORY12695.1 - 1.3e-20 73.9 0.0 1.8e-20 73.4 0.0 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 ORY12695.1 - 7.6e-12 45.1 0.0 1.6e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.6 ORY12695.1 - 0.065 13.8 0.0 0.11 13.1 0.0 1.3 1 0 0 1 1 1 0 Complex1_LYR-like MTS PF05175.14 ORY12696.1 - 0.00015 21.4 0.0 0.00025 20.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 ORY12696.1 - 0.0096 16.6 0.0 0.029 15.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY12696.1 - 0.013 16.3 0.0 0.023 15.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Pkinase PF00069.25 ORY12697.1 - 2.3e-29 102.6 0.0 4.6e-29 101.6 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY12697.1 - 3.3e-16 59.4 0.0 3e-14 52.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 ORY12697.1 - 0.04 13.8 0.0 0.087 12.7 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 ORY12697.1 - 0.21 10.5 0.0 0.29 10.0 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase LSM PF01423.22 ORY12698.1 - 3.1e-15 55.6 0.1 3.9e-15 55.3 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 ORY12698.1 - 5.6e-05 23.2 0.0 7.2e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain TauD PF02668.16 ORY12699.1 - 8.5e-29 101.2 0.0 1.2e-28 100.7 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family A_thal_3526 PF09713.10 ORY12699.1 - 0.16 12.2 0.1 0.3 11.4 0.1 1.3 1 0 0 1 1 1 0 Plant protein 1589 of unknown function (A_thal_3526) DUF1744 PF08490.12 ORY12701.1 - 1.5e-152 507.8 0.0 2.2e-152 507.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.19 ORY12701.1 - 1.2e-82 277.8 0.4 2.3e-82 276.9 0.4 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 ORY12701.1 - 5.8e-16 58.3 0.0 1.1e-12 47.5 0.1 3.6 3 1 0 3 3 3 2 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 ORY12701.1 - 2e-09 37.5 0.3 6.5e-09 35.8 0.3 1.8 1 1 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 ORY12701.1 - 3e-06 27.3 0.2 1.4e-05 25.2 0.0 2.2 2 0 0 2 2 2 1 RNase_H superfamily DUF3767 PF12597.8 ORY12702.1 - 2.5e-23 81.8 0.1 2.5e-23 81.8 0.1 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF3767) Bac_export_2 PF01312.19 ORY12702.1 - 0.017 14.4 0.5 0.017 14.4 0.5 1.1 1 0 0 1 1 1 0 FlhB HrpN YscU SpaS Family MRP-S26 PF14943.6 ORY12702.1 - 0.091 12.7 9.3 0.12 12.3 9.3 1.1 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 Mitoc_L55 PF09776.9 ORY12702.1 - 1.1 9.0 7.1 1.8 8.3 7.1 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L55 DUF1682 PF07946.14 ORY12702.1 - 1.3 8.2 11.8 1.7 7.8 11.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DDRGK PF09756.9 ORY12702.1 - 1.7 8.2 14.4 2.2 7.8 14.4 1.1 1 0 0 1 1 1 0 DDRGK domain DUF3886 PF13025.6 ORY12702.1 - 8.2 6.7 18.0 1.9 8.7 14.3 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3886) DUF2263 PF10021.9 ORY12704.1 - 2e-17 63.9 0.0 9.2e-16 58.5 0.0 2.6 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2263) Macro PF01661.21 ORY12704.1 - 0.044 13.8 0.0 0.067 13.2 0.0 1.3 1 0 0 1 1 1 0 Macro domain DNA_pol_A_exo1 PF01612.20 ORY12705.1 - 5e-39 133.8 0.1 8.3e-39 133.1 0.1 1.4 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.12 ORY12705.1 - 2e-28 98.9 0.3 1.3e-26 93.1 0.1 2.5 2 0 0 2 2 2 1 PMC2NT (NUC016) domain HRDC PF00570.23 ORY12705.1 - 5.1e-13 48.8 0.0 1.5e-12 47.3 0.0 1.9 1 0 0 1 1 1 1 HRDC domain UPF0203 PF05254.12 ORY12706.1 - 1.4e-26 92.5 3.1 1.7e-26 92.3 3.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) COX17 PF05051.13 ORY12706.1 - 0.00027 21.2 0.7 0.00027 21.2 0.7 2.0 2 1 0 2 2 2 1 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.10 ORY12706.1 - 0.006 16.6 7.2 0.052 13.6 0.2 2.5 2 1 1 3 3 3 2 Cytochrome c oxidase biogenesis protein Cmc1 like DUF5339 PF17274.2 ORY12706.1 - 0.061 14.2 3.8 0.21 12.5 0.7 2.5 2 1 0 2 2 2 0 Family of unknown function (DUF5339) UCR_hinge PF02320.16 ORY12706.1 - 0.061 13.5 4.0 1.3 9.2 0.2 2.1 1 1 1 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein MAPEG PF01124.18 ORY12707.1 - 1.1e-19 70.6 2.7 1.3e-19 70.4 2.7 1.1 1 0 0 1 1 1 1 MAPEG family tRNA_NucTransf2 PF09249.11 ORY12707.1 - 0.016 15.4 1.8 0.034 14.4 1.8 1.4 1 0 0 1 1 1 0 tRNA nucleotidyltransferase, second domain VHS PF00790.19 ORY12708.1 - 1.8e-47 160.8 0.0 4.6e-47 159.4 0.0 1.8 1 0 0 1 1 1 1 VHS domain GAT PF03127.14 ORY12708.1 - 2.2e-20 72.7 1.4 9e-20 70.8 0.4 2.5 2 0 0 2 2 2 1 GAT domain Alpha_adaptinC2 PF02883.20 ORY12708.1 - 1.7e-17 63.7 0.3 4.4e-17 62.4 0.3 1.7 1 0 0 1 1 1 1 Adaptin C-terminal domain GGA_N-GAT PF18308.1 ORY12708.1 - 2e-07 30.5 0.7 3e-06 26.8 0.0 3.0 4 0 0 4 4 4 1 GGA N-GAT domain Mei5 PF10376.9 ORY12708.1 - 0.1 12.5 2.7 0.15 11.9 2.0 1.7 1 1 0 1 1 1 0 Double-strand recombination repair protein Peptidase_S46 PF10459.9 ORY12708.1 - 0.94 8.0 5.6 1.4 7.5 5.6 1.1 1 0 0 1 1 1 0 Peptidase S46 Glyco_hydro_47 PF01532.20 ORY12709.1 - 2.3e-175 583.9 0.0 2.7e-175 583.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Abhydrolase_2 PF02230.16 ORY12710.1 - 3e-33 115.4 0.0 3.8e-33 115.1 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Cutinase PF01083.22 ORY12710.1 - 0.0019 18.2 0.0 0.004 17.1 0.0 1.5 2 0 0 2 2 2 1 Cutinase Abhydrolase_6 PF12697.7 ORY12710.1 - 0.0079 16.8 0.0 0.012 16.3 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.13 ORY12710.1 - 0.07 12.8 0.0 0.088 12.5 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase (FSH1) zf-HIT PF04438.16 ORY12711.1 - 3.5e-09 36.4 4.8 5.9e-09 35.6 4.8 1.4 1 0 0 1 1 1 1 HIT zinc finger Dsh_C PF12316.8 ORY12711.1 - 1.1 9.6 10.0 0.57 10.6 3.8 2.1 2 0 0 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal adh_short PF00106.25 ORY12712.1 - 3.4e-20 72.3 0.0 1.1e-18 67.4 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY12712.1 - 7.7e-14 51.8 0.0 7.9e-13 48.5 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY12712.1 - 0.00015 21.7 0.0 0.00025 21.0 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF3251 PF11622.8 ORY12712.1 - 0.15 11.7 0.2 0.33 10.6 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3251) Pil1 PF13805.6 ORY12713.1 - 0.23 10.9 8.7 0.11 11.9 4.7 2.7 2 1 0 2 2 2 0 Eisosome component PIL1 HeLo PF14479.6 ORY12713.1 - 0.66 9.8 3.4 0.31 10.9 0.2 2.1 2 1 0 2 2 2 0 Prion-inhibition and propagation RTA1 PF04479.13 ORY12715.1 - 3.7e-31 108.4 3.2 4.2e-31 108.2 3.2 1.0 1 0 0 1 1 1 1 RTA1 like protein WD40 PF00400.32 ORY12716.1 - 1.1e-24 86.2 13.8 6.4e-06 26.8 0.1 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat PQQ_3 PF13570.6 ORY12716.1 - 6e-08 32.9 2.2 0.0099 16.3 0.0 4.8 5 0 0 5 5 5 2 PQQ-like domain Nup160 PF11715.8 ORY12716.1 - 0.0017 17.1 0.8 0.033 12.8 0.1 2.9 1 1 3 4 4 4 1 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 ORY12716.1 - 0.0065 16.8 1.2 0.7 10.2 0.0 3.0 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 ORY12716.1 - 0.0091 15.4 0.0 9.1 5.5 0.0 3.2 2 2 1 3 3 3 2 WD40-like domain Coatomer_WDAD PF04053.14 ORY12716.1 - 0.22 10.5 0.1 0.41 9.6 0.1 1.4 1 0 0 1 1 1 0 Coatomer WD associated region Ribo_biogen_C PF04034.13 ORY12717.1 - 1e-49 167.5 0.0 1.5e-49 167.0 0.0 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 ORY12717.1 - 3.3e-11 42.8 0.8 7.4e-11 41.7 0.8 1.6 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI BUD22 PF09073.10 ORY12717.1 - 0.01 15.2 22.9 0.015 14.6 22.9 1.2 1 0 0 1 1 1 0 BUD22 DUF5487 PF17589.2 ORY12719.1 - 0.08 13.2 0.8 0.26 11.6 0.4 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5487) DUF3597 PF12200.8 ORY12719.1 - 0.082 13.4 0.7 0.59 10.7 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF3597) DUF5427 PF10310.9 ORY12719.1 - 0.17 10.8 6.4 0.24 10.3 6.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5427) BTB PF00651.31 ORY12722.1 - 0.00083 19.6 0.0 0.0014 18.9 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Catalase_C PF18011.1 ORY12724.1 - 0.065 12.9 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 C-terminal domain found in long catalases GRIM-19 PF06212.12 ORY12725.1 - 3.4e-22 78.8 0.1 1.2e-21 77.0 0.1 1.7 1 1 0 1 1 1 1 GRIM-19 protein tRNA_m1G_MT PF01746.21 ORY12726.1 - 2.8e-26 92.4 0.0 5.6e-26 91.5 0.0 1.5 1 1 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase TLD PF07534.16 ORY12727.1 - 1.9e-26 92.9 0.0 1.2e-14 54.7 0.0 2.3 2 0 0 2 2 2 2 TLD FHA PF00498.26 ORY12728.1 - 3.4e-14 52.9 0.0 6.5e-14 52.0 0.0 1.5 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 ORY12728.1 - 8.4e-05 22.8 0.0 0.0091 16.3 0.0 2.2 1 1 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain DUF2935 PF11155.8 ORY12729.1 - 0.11 12.8 3.9 27 5.1 0.4 4.0 2 1 0 2 2 2 0 Domain of unknown function (DUF2935) Raptor_N PF14538.6 ORY12729.1 - 0.81 9.6 3.1 15 5.5 0.5 2.8 2 0 0 2 2 2 0 Raptor N-terminal CASPase like domain KASH_CCD PF14662.6 ORY12729.1 - 1.2 8.9 42.9 0.48 10.2 12.1 3.8 3 1 0 3 3 3 0 Coiled-coil region of CCDC155 or KASH BLOC1_2 PF10046.9 ORY12729.1 - 3.7 7.9 23.4 0.28 11.5 7.5 4.5 4 0 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4201 PF13870.6 ORY12729.1 - 3.8 7.2 38.0 0.34 10.6 8.6 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4201) Bap31_Bap29_C PF18035.1 ORY12729.1 - 9.5 6.3 13.9 27 4.9 0.0 4.9 4 0 0 4 4 4 0 Bap31/Bap29 cytoplasmic coiled-coil domain COesterase PF00135.28 ORY12731.1 - 5.9e-71 239.9 0.0 1.2e-70 238.8 0.0 1.4 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 ORY12731.1 - 1.1e-05 25.4 0.2 6.8e-05 22.8 0.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 ORY12731.1 - 0.18 10.7 0.0 0.44 9.4 0.0 1.6 2 0 0 2 2 2 0 Steryl acetyl hydrolase CsbD PF05532.12 ORY12732.1 - 0.002 18.0 16.0 0.043 13.7 5.0 3.2 2 1 1 3 3 3 2 CsbD-like DUF4629 PF15442.6 ORY12732.1 - 0.025 14.8 4.1 0.029 14.6 4.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4629) DUF883 PF05957.13 ORY12732.1 - 0.21 12.2 3.6 0.58 10.8 0.7 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) ATP-synt_B PF00430.18 ORY12732.1 - 0.22 11.6 5.2 0.27 11.3 2.1 2.0 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) YtxH PF12732.7 ORY12732.1 - 0.23 12.0 6.8 3 8.5 6.8 2.1 1 1 0 1 1 1 0 YtxH-like protein DivIVA PF05103.13 ORY12732.1 - 0.45 10.6 4.2 0.37 10.9 1.6 1.8 1 1 1 2 2 2 0 DivIVA protein LEA_4 PF02987.16 ORY12732.1 - 3.4 7.8 13.3 1.5 8.9 7.5 2.6 1 1 1 2 2 2 0 Late embryogenesis abundant protein Peptidase_C14 PF00656.22 ORY12733.1 - 4.9e-62 210.1 0.0 6.5e-62 209.7 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Tmemb_18A PF09771.9 ORY12734.1 - 0.019 15.4 0.0 0.027 14.9 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 188 Sec7 PF01369.20 ORY12735.1 - 3e-24 85.7 0.0 6e-24 84.7 0.0 1.4 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.6 ORY12735.1 - 6.7e-19 68.4 0.0 4.9e-18 65.6 0.0 2.6 3 0 0 3 3 3 1 Pleckstrin homology domain HAD_2 PF13419.6 ORY12737.1 - 1.2e-08 35.2 0.0 1.9e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ORY12737.1 - 3.1e-05 24.0 0.0 6.1e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 ORY12737.1 - 8.3e-05 23.0 0.0 0.00043 20.6 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HNH PF01844.23 ORY12739.1 - 0.018 15.2 0.1 0.043 14.0 0.1 1.7 1 1 0 1 1 1 0 HNH endonuclease PP28 PF10252.9 ORY12740.1 - 2.9e-28 98.2 19.0 2.9e-28 98.2 19.0 2.9 2 1 1 3 3 3 2 Casein kinase substrate phosphoprotein PP28 EF-1_beta_acid PF10587.9 ORY12740.1 - 0.061 13.8 5.0 0.061 13.8 5.0 6.3 5 2 0 6 6 6 0 Eukaryotic elongation factor 1 beta central acidic region Piwi PF02171.17 ORY12741.1 - 9.3e-72 241.8 0.0 1.4e-71 241.2 0.0 1.2 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 ORY12741.1 - 4e-18 66.3 0.0 8.8e-18 65.2 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 ORY12741.1 - 2.9e-17 62.1 0.2 7.3e-17 60.8 0.2 1.8 1 0 0 1 1 1 1 Argonaute linker 1 domain PAZ PF02170.22 ORY12741.1 - 3.1e-15 56.2 0.3 6.4e-15 55.2 0.3 1.5 1 0 0 1 1 1 1 PAZ domain ArgoL2 PF16488.5 ORY12741.1 - 6.8e-09 35.9 0.0 1.5e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 Argonaute linker 2 domain ArgoMid PF16487.5 ORY12741.1 - 1.3e-07 31.8 0.0 5.2e-06 26.6 0.0 2.8 1 1 1 2 2 2 1 Mid domain of argonaute Suf PF05843.14 ORY12742.1 - 2.2e-79 267.5 0.0 2.2e-79 267.5 0.0 4.0 5 1 0 5 5 5 2 Suppressor of forked protein (Suf) TPR_14 PF13428.6 ORY12742.1 - 0.0051 17.5 5.6 4.9 8.2 0.1 5.2 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 ORY12742.1 - 0.018 15.5 0.2 0.71 10.4 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat UNC-50 PF05216.13 ORY12743.1 - 7.7e-88 293.8 8.6 8.7e-88 293.6 8.6 1.0 1 0 0 1 1 1 1 UNC-50 family GTP_EFTU PF00009.27 ORY12744.1 - 2.9e-32 111.8 2.9 1.8e-30 105.9 2.9 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 ORY12744.1 - 1.2e-24 86.4 1.2 2.8e-24 85.3 1.2 1.6 1 0 0 1 1 1 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 ORY12744.1 - 1.5e-09 37.9 0.2 3.2e-09 36.9 0.2 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase IF2_N PF04760.15 ORY12744.1 - 1.9e-08 34.0 0.0 4.4e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region RsgA_GTPase PF03193.16 ORY12744.1 - 3.8e-05 23.7 0.6 0.00061 19.7 0.1 2.4 1 1 1 2 2 2 1 RsgA GTPase Arf PF00025.21 ORY12744.1 - 0.00012 21.6 0.0 0.00025 20.5 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family zf-CCHC PF00098.23 ORY12744.1 - 0.00033 20.6 2.2 0.00089 19.2 2.2 1.8 1 0 0 1 1 1 1 Zinc knuckle FeoB_N PF02421.18 ORY12744.1 - 0.00078 19.0 0.1 0.0018 17.8 0.1 1.7 1 0 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.10 ORY12744.1 - 0.00087 18.8 0.2 0.00087 18.8 0.2 2.0 2 1 0 2 2 1 1 Signal recognition particle receptor beta subunit GTP_EFTU_D2 PF03144.25 ORY12744.1 - 0.0012 19.2 2.6 1.1 9.6 0.3 3.2 2 0 0 2 2 2 2 Elongation factor Tu domain 2 Roc PF08477.13 ORY12744.1 - 0.025 14.8 0.0 0.053 13.8 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 ORY12744.1 - 0.035 13.7 0.0 0.062 12.9 0.0 1.4 1 0 0 1 1 1 0 Ras family zf-CCHC_2 PF13696.6 ORY12744.1 - 0.041 13.7 3.9 0.072 12.9 3.9 1.4 1 0 0 1 1 1 0 Zinc knuckle Hydrolase_6 PF13344.6 ORY12744.1 - 0.047 13.8 0.0 4.5 7.4 0.0 2.6 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase SIS_2 PF13580.6 ORY12744.1 - 0.091 12.8 2.4 0.99 9.4 0.0 2.9 2 1 1 3 3 3 0 SIS domain Dynamin_N PF00350.23 ORY12744.1 - 0.11 12.6 0.9 12 6.0 0.1 3.3 2 1 1 3 3 3 0 Dynamin family DUF4355 PF14265.6 ORY12744.1 - 2.3 8.5 20.8 0.18 12.0 6.4 3.7 4 0 0 4 4 3 0 Domain of unknown function (DUF4355) DUF3760 PF12586.8 ORY12745.1 - 0.02 15.1 0.1 0.1 12.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3760) DEAD PF00270.29 ORY12747.1 - 2.3e-41 141.5 0.0 3.2e-41 141.0 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY12747.1 - 3.7e-28 98.1 0.6 6.6e-27 94.1 0.4 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY12747.1 - 0.0022 18.0 0.0 0.0044 17.0 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 ORY12747.1 - 0.033 13.5 0.0 0.068 12.5 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Rhomboid PF01694.22 ORY12748.1 - 3.1e-17 63.0 5.2 3.1e-17 63.0 5.2 1.5 2 0 0 2 2 2 1 Rhomboid family ELO PF01151.18 ORY12748.1 - 0.016 14.8 5.7 0.03 13.8 5.7 1.5 1 1 0 1 1 1 0 GNS1/SUR4 family zf-C2H2 PF00096.26 ORY12749.1 - 5e-08 33.0 20.0 0.034 14.6 0.2 4.5 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY12749.1 - 6.2e-06 26.6 20.4 0.0082 16.9 0.3 4.6 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_8 PF15909.5 ORY12749.1 - 0.0022 18.2 5.5 0.76 10.1 0.5 2.3 1 1 1 2 2 2 2 C2H2-type zinc ribbon FOXP-CC PF16159.5 ORY12749.1 - 0.03 14.9 13.4 0.31 11.7 0.2 3.2 1 1 2 3 3 3 0 FOXP coiled-coil domain zf-met PF12874.7 ORY12749.1 - 0.039 14.4 11.7 0.39 11.2 0.3 4.2 4 0 0 4 4 4 0 Zinc-finger of C2H2 type Mut7-C PF01927.16 ORY12749.1 - 0.046 13.8 2.1 0.073 13.2 2.1 1.3 1 0 0 1 1 1 0 Mut7-C RNAse domain zf-H2C2_2 PF13465.6 ORY12749.1 - 0.15 12.5 0.1 0.15 12.5 0.1 3.0 3 0 0 3 3 3 0 Zinc-finger double domain zf-Sec23_Sec24 PF04810.15 ORY12749.1 - 4.8 7.3 8.7 3.6 7.7 0.2 3.5 4 1 0 4 4 4 0 Sec23/Sec24 zinc finger Bromodomain PF00439.25 ORY12751.1 - 4.7e-19 68.3 0.6 2.1e-18 66.2 0.3 2.1 2 0 0 2 2 2 1 Bromodomain Bromo_TP PF07524.13 ORY12751.1 - 1.2e-05 25.2 0.0 3.1e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Bromodomain associated VanZ PF04892.12 ORY12752.1 - 5.9e-07 30.2 0.7 7.8e-07 29.8 0.7 1.2 1 0 0 1 1 1 1 VanZ like family FtsK_4TM PF13491.6 ORY12752.1 - 0.037 13.7 0.9 5.3 6.7 0.0 2.1 1 1 1 2 2 2 0 4TM region of DNA translocase FtsK/SpoIIIE DUF2279 PF10043.9 ORY12752.1 - 0.088 13.6 0.0 0.15 12.9 0.0 1.3 1 0 0 1 1 1 0 Predicted periplasmic lipoprotein (DUF2279) Phage_holin_2_4 PF16082.5 ORY12752.1 - 1 9.1 2.8 1.4 8.7 0.1 2.3 3 0 0 3 3 3 0 Bacteriophage holin family, superfamily II-like Ribosomal_S26e PF01283.19 ORY12753.1 - 9e-52 174.1 8.0 1.1e-51 173.8 8.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e zf_CopZ PF18423.1 ORY12753.1 - 0.054 13.5 1.9 0.061 13.3 0.0 2.0 3 0 0 3 3 3 0 Zinc binding domain DUF1918 PF08940.11 ORY12753.1 - 0.083 12.5 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) DUF4668 PF15701.5 ORY12753.1 - 0.085 12.7 0.4 0.13 12.0 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4668) SF1-HH PF16275.5 ORY12753.1 - 0.33 11.3 2.2 0.5 10.7 2.2 1.5 1 1 0 1 1 1 0 Splicing factor 1 helix-hairpin domain CBS PF00571.28 ORY12754.1 - 7.1e-35 119.3 6.4 1.6e-09 38.1 0.0 4.9 5 0 0 5 5 5 4 CBS domain PB1 PF00564.24 ORY12754.1 - 5.4e-09 35.9 0.1 1.9e-08 34.1 0.0 2.0 2 0 0 2 2 2 1 PB1 domain Importin_rep_4 PF18808.1 ORY12755.1 - 2.8e-35 120.5 3.0 7.9e-34 115.8 0.8 3.9 2 1 1 3 3 3 1 Importin repeat Importin_rep_5 PF18816.1 ORY12755.1 - 4.8e-21 74.8 0.0 1.9e-20 72.9 0.0 2.2 1 0 0 1 1 1 1 Importin repeat HEAT_EZ PF13513.6 ORY12755.1 - 7.6e-18 64.6 17.1 9e-10 38.8 0.3 8.3 8 1 2 10 10 9 3 HEAT-like repeat HEAT PF02985.22 ORY12755.1 - 4.6e-16 57.5 6.2 0.01 16.0 0.0 10.0 9 1 1 10 10 10 3 HEAT repeat HEAT_2 PF13646.6 ORY12755.1 - 3.6e-15 56.1 8.1 0.00048 20.5 0.0 7.6 4 2 4 8 8 8 2 HEAT repeats Importin_rep_6 PF18829.1 ORY12755.1 - 2.4e-13 50.1 0.7 2.4e-13 50.1 0.7 3.3 4 0 0 4 4 4 1 Importin repeat 6 Vac14_Fab1_bd PF12755.7 ORY12755.1 - 8.1e-10 39.2 0.0 0.036 14.6 0.0 5.5 4 1 2 6 6 5 2 Vacuolar 14 Fab1-binding region MMS19_C PF12460.8 ORY12755.1 - 2.3e-08 33.6 1.7 1.2e-07 31.2 1.5 2.4 1 1 0 1 1 1 1 RNAPII transcription regulator C-terminal DUF3385 PF11865.8 ORY12755.1 - 3.7e-08 33.4 0.1 0.12 12.3 0.0 6.0 6 0 0 6 6 6 2 Domain of unknown function (DUF3385) RIX1 PF08167.12 ORY12755.1 - 7e-07 29.2 1.0 0.0072 16.1 0.0 4.6 4 1 1 5 5 5 1 rRNA processing/ribosome biogenesis Adaptin_N PF01602.20 ORY12755.1 - 1.9e-05 23.4 0.1 0.00078 18.1 0.1 2.6 3 0 0 3 3 3 1 Adaptin N terminal region CLASP_N PF12348.8 ORY12755.1 - 3.3e-05 23.6 0.0 0.025 14.1 0.1 3.6 3 1 0 3 3 3 1 CLASP N terminal Cnd1 PF12717.7 ORY12755.1 - 7.2e-05 22.9 0.0 0.0064 16.6 0.0 3.5 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 DUF4042 PF13251.6 ORY12755.1 - 0.0026 17.5 0.0 20 4.8 0.0 4.2 4 0 0 4 4 4 0 Domain of unknown function (DUF4042) DRIM PF07539.12 ORY12755.1 - 0.013 13.9 0.5 0.1 10.9 0.1 2.6 3 0 0 3 3 3 0 Down-regulated in metastasis Sec6 PF06046.13 ORY12755.1 - 0.021 13.2 0.5 0.064 11.6 0.1 1.9 2 0 0 2 2 2 0 Exocyst complex component Sec6 Arm PF00514.23 ORY12755.1 - 0.026 14.5 4.7 5.7 7.1 0.0 4.6 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat MMS19_N PF14500.6 ORY12755.1 - 0.038 13.6 0.2 1.7 8.1 0.1 3.4 3 0 0 3 3 3 0 Dos2-interacting transcription regulator of RNA-Pol-II RTP1_C1 PF10363.9 ORY12755.1 - 0.061 13.5 0.1 0.86 9.8 0.2 2.9 3 0 0 3 3 2 0 Required for nuclear transport of RNA pol II C-terminus 1 AAA PF00004.29 ORY12756.1 - 4.1e-42 143.7 0.0 7.2e-42 143.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 ORY12756.1 - 5.7e-30 103.1 0.2 3.9e-29 100.4 0.2 2.4 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 ORY12756.1 - 4.2e-23 81.2 4.8 4.2e-23 81.2 4.8 1.9 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain AAA_lid_3 PF17862.1 ORY12756.1 - 4.9e-06 26.3 0.0 1.6e-05 24.6 0.0 1.9 2 0 0 2 2 1 1 AAA+ lid domain RuvB_N PF05496.12 ORY12756.1 - 1.4e-05 24.9 0.0 3e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 ORY12756.1 - 2.8e-05 24.6 0.0 0.00024 21.5 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 ORY12756.1 - 3.8e-05 23.7 0.0 0.00018 21.5 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 ORY12756.1 - 5.8e-05 23.4 0.0 0.012 16.0 0.0 2.6 2 0 0 2 2 2 1 RNA helicase IstB_IS21 PF01695.17 ORY12756.1 - 0.00011 22.0 0.0 0.00026 20.8 0.0 1.6 1 1 0 1 1 1 1 IstB-like ATP binding protein AAA_2 PF07724.14 ORY12756.1 - 0.00017 21.8 0.0 0.0016 18.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 ORY12756.1 - 0.00023 20.5 0.0 0.00041 19.7 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain DUF815 PF05673.13 ORY12756.1 - 0.0003 20.0 0.0 0.0016 17.7 0.0 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 ORY12756.1 - 0.00036 20.8 0.1 0.02 15.2 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_14 PF13173.6 ORY12756.1 - 0.00061 19.8 0.0 0.0012 18.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 ORY12756.1 - 0.00074 20.1 0.1 0.0033 18.0 0.0 2.1 2 1 0 2 2 1 1 AAA domain AAA_33 PF13671.6 ORY12756.1 - 0.0019 18.4 0.0 0.0057 16.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 ORY12756.1 - 0.004 16.9 0.0 0.012 15.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 ORY12756.1 - 0.0062 16.1 0.0 0.038 13.5 0.0 2.2 2 1 0 2 2 2 1 P-loop containing dynein motor region AAA_17 PF13207.6 ORY12756.1 - 0.015 15.7 0.1 0.054 13.9 0.0 2.0 2 0 0 2 2 1 0 AAA domain Mg_chelatase PF01078.21 ORY12756.1 - 0.021 14.2 0.0 0.081 12.3 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Torsin PF06309.11 ORY12756.1 - 0.029 14.5 0.0 0.085 13.0 0.0 1.7 2 0 0 2 2 1 0 Torsin Phage_GPO PF05929.11 ORY12756.1 - 0.043 13.4 0.2 0.075 12.7 0.2 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Sigma54_activat PF00158.26 ORY12756.1 - 0.054 13.2 0.0 0.2 11.4 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain Parvo_NS1 PF01057.17 ORY12756.1 - 0.058 12.5 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_25 PF13481.6 ORY12756.1 - 0.07 12.7 0.1 0.72 9.4 0.1 2.2 1 1 0 2 2 2 0 AAA domain Use1 PF09753.9 ORY12756.1 - 0.079 12.7 0.7 0.16 11.7 0.7 1.4 1 0 0 1 1 1 0 Membrane fusion protein Use1 PhoH PF02562.16 ORY12756.1 - 0.085 12.3 0.1 0.16 11.4 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein USP8_dimer PF08969.11 ORY12756.1 - 0.091 12.9 3.7 0.15 12.3 3.0 1.8 2 0 0 2 2 1 0 USP8 dimerisation domain NACHT PF05729.12 ORY12756.1 - 0.12 12.3 0.0 0.55 10.1 0.0 2.1 1 1 0 1 1 1 0 NACHT domain AFG1_ATPase PF03969.16 ORY12756.1 - 0.2 10.5 0.0 0.36 9.7 0.0 1.4 1 0 0 1 1 1 0 AFG1-like ATPase Cytidylate_kin PF02224.18 ORY12756.1 - 0.24 11.1 1.1 0.53 10.0 0.1 2.1 2 1 1 3 3 3 0 Cytidylate kinase Prefoldin_2 PF01920.20 ORY12757.1 - 4.4e-22 78.0 10.5 5.8e-22 77.7 10.5 1.1 1 0 0 1 1 1 1 Prefoldin subunit Tropomyosin_1 PF12718.7 ORY12757.1 - 0.00031 20.9 9.7 0.0011 19.2 2.9 2.0 2 0 0 2 2 2 1 Tropomyosin like Spc7 PF08317.11 ORY12757.1 - 0.0016 17.4 8.9 0.002 17.1 8.9 1.0 1 0 0 1 1 1 1 Spc7 kinetochore protein YabA PF06156.13 ORY12757.1 - 0.0033 18.0 2.9 0.6 10.8 0.5 2.1 2 0 0 2 2 2 1 Initiation control protein YabA Spc24 PF08286.11 ORY12757.1 - 0.0096 16.2 9.1 0.033 14.4 3.9 2.1 1 1 1 2 2 2 1 Spc24 subunit of Ndc80 FTA4 PF13093.6 ORY12757.1 - 0.011 15.7 1.0 0.013 15.4 1.0 1.1 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DUF3584 PF12128.8 ORY12757.1 - 0.012 13.2 6.1 0.014 12.9 6.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Taxilin PF09728.9 ORY12757.1 - 0.018 14.3 3.2 0.018 14.3 3.2 2.0 2 0 0 2 2 2 0 Myosin-like coiled-coil protein TMF_TATA_bd PF12325.8 ORY12757.1 - 0.02 15.1 8.1 0.055 13.7 2.0 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding End3 PF12761.7 ORY12757.1 - 0.021 15.0 6.9 0.024 14.8 6.9 1.1 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 GAS PF13851.6 ORY12757.1 - 0.022 14.1 8.3 0.079 12.3 2.7 2.0 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding APG6_N PF17675.1 ORY12757.1 - 0.031 14.8 13.0 0.58 10.7 0.4 2.0 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF4349 PF14257.6 ORY12757.1 - 0.033 13.6 3.9 0.085 12.3 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) DUF3727 PF12527.8 ORY12757.1 - 0.036 14.3 0.5 3.1 8.1 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3727) ABC_tran_CTD PF16326.5 ORY12757.1 - 0.036 14.3 9.8 0.26 11.6 1.8 2.7 2 1 0 2 2 2 0 ABC transporter C-terminal domain COG5 PF10392.9 ORY12757.1 - 0.046 13.9 0.9 0.26 11.4 0.1 2.0 2 0 0 2 2 2 0 Golgi transport complex subunit 5 Prefoldin PF02996.17 ORY12757.1 - 0.051 13.5 10.0 0.15 11.9 0.9 2.2 2 0 0 2 2 2 0 Prefoldin subunit DHR10 PF18595.1 ORY12757.1 - 0.054 13.5 11.4 0.06 13.4 4.4 2.1 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain Prefoldin_3 PF13758.6 ORY12757.1 - 0.066 13.3 3.5 0.12 12.5 3.5 1.4 1 1 0 1 1 1 0 Prefoldin subunit DUF4407 PF14362.6 ORY12757.1 - 0.092 12.1 3.4 0.12 11.7 3.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) JIP_LZII PF16471.5 ORY12757.1 - 0.1 12.8 5.8 0.085 13.0 1.6 2.2 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II FlaC_arch PF05377.11 ORY12757.1 - 0.11 12.9 10.0 0.9 10.0 0.9 3.0 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) DivIC PF04977.15 ORY12757.1 - 0.12 12.1 14.1 0.39 10.5 1.1 3.1 2 1 1 3 3 3 0 Septum formation initiator NPV_P10 PF05531.12 ORY12757.1 - 0.12 12.8 5.7 4.8 7.7 1.9 2.2 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein Swi5 PF07061.11 ORY12757.1 - 0.16 12.1 7.9 0.77 9.9 3.6 2.2 2 0 0 2 2 2 0 Swi5 CLZ PF16526.5 ORY12757.1 - 0.16 12.3 4.8 1.3 9.4 0.5 2.4 2 1 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF4201 PF13870.6 ORY12757.1 - 0.19 11.5 8.7 0.21 11.3 1.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) DUF4200 PF13863.6 ORY12757.1 - 0.21 12.0 8.9 2.5 8.5 1.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) YlqD PF11068.8 ORY12757.1 - 0.23 11.8 11.7 0.76 10.1 1.3 2.0 2 0 0 2 2 2 0 YlqD protein Rx_N PF18052.1 ORY12757.1 - 0.26 11.6 5.9 1.1 9.6 1.6 2.2 2 0 0 2 2 2 0 Rx N-terminal domain Med9 PF07544.13 ORY12757.1 - 0.37 10.9 7.1 3.8 7.7 1.9 2.2 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 HMMR_N PF15905.5 ORY12757.1 - 0.44 10.0 10.1 9.2 5.6 9.6 2.1 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal CENP-F_leu_zip PF10473.9 ORY12757.1 - 0.57 10.2 11.5 0.48 10.4 4.0 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spectrin PF00435.21 ORY12757.1 - 0.65 10.5 7.4 1.8 9.1 3.1 2.1 2 0 0 2 2 2 0 Spectrin repeat WEMBL PF05701.11 ORY12757.1 - 0.94 8.1 9.8 3.5 6.2 9.8 1.7 1 1 0 1 1 1 0 Weak chloroplast movement under blue light bZIP_1 PF00170.21 ORY12757.1 - 0.99 9.6 8.9 3.1 8.0 2.6 2.5 2 1 1 3 3 3 0 bZIP transcription factor Occludin_ELL PF07303.13 ORY12757.1 - 1.1 10.0 6.1 1.2 9.9 2.8 2.0 1 1 1 2 2 2 0 Occludin homology domain ERM PF00769.19 ORY12757.1 - 1.1 9.0 9.8 2.4 7.9 9.8 1.4 1 1 0 1 1 1 0 Ezrin/radixin/moesin family GPS2_interact PF15784.5 ORY12757.1 - 1.2 9.6 7.9 0.87 10.1 0.3 2.2 2 0 0 2 2 2 0 G-protein pathway suppressor 2-interacting domain Sec34 PF04136.15 ORY12757.1 - 1.3 8.9 6.2 2.6 7.9 1.1 2.0 2 0 0 2 2 2 0 Sec34-like family LPP PF04728.13 ORY12757.1 - 1.4 9.4 5.4 19 5.8 0.1 2.7 2 1 0 2 2 2 0 Lipoprotein leucine-zipper DUF4686 PF15742.5 ORY12757.1 - 1.5 7.8 13.4 2.7 7.0 13.4 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4686) TMF_DNA_bd PF12329.8 ORY12757.1 - 2.1 8.4 13.6 4.5 7.3 0.3 2.9 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Rho_Binding PF08912.11 ORY12757.1 - 3 8.7 11.2 4.8 8.1 4.4 2.4 2 1 0 2 2 2 0 Rho Binding TolA_bind_tri PF16331.5 ORY12757.1 - 3.1 8.0 10.1 0.58 10.3 5.3 2.1 2 0 0 2 2 2 0 TolA binding protein trimerisation DUF1664 PF07889.12 ORY12757.1 - 3.2 7.8 9.8 5.7 7.0 1.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) ADIP PF11559.8 ORY12757.1 - 4.2 7.4 10.9 6.5 6.8 0.3 2.1 1 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding ZapB PF06005.12 ORY12757.1 - 5.5 7.5 15.7 1.4e+02 3.0 15.7 2.2 1 1 0 1 1 1 0 Cell division protein ZapB Csm1_N PF18504.1 ORY12757.1 - 5.8 7.3 11.7 10 6.5 0.2 3.0 2 1 1 3 3 3 0 Csm1 N-terminal domain Val_tRNA-synt_C PF10458.9 ORY12757.1 - 7 7.0 9.8 18 5.7 0.2 3.0 2 1 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm BTB PF00651.31 ORY12758.1 - 6e-06 26.4 0.0 9.7e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain eIF-1a PF01176.19 ORY12760.1 - 0.046 13.5 0.0 0.084 12.7 0.0 1.4 1 0 0 1 1 1 0 Translation initiation factor 1A / IF-1 BTB PF00651.31 ORY12761.1 - 0.0031 17.7 0.0 0.0047 17.1 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain EspG PF06872.11 ORY12761.1 - 0.16 10.5 0.0 0.21 10.1 0.0 1.1 1 0 0 1 1 1 0 EspG protein LRR_4 PF12799.7 ORY12763.1 - 0.14 12.6 2.2 3 8.4 0.0 3.9 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) ECH_1 PF00378.20 ORY12764.1 - 7.3e-40 136.8 0.0 1.7e-39 135.7 0.0 1.5 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ORY12764.1 - 1.6e-26 93.6 0.0 2.4e-26 93.0 0.0 1.3 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase RsbRD_N PF14361.6 ORY12764.1 - 0.13 13.0 0.0 0.24 12.1 0.0 1.5 1 0 0 1 1 1 0 RsbT co-antagonist protein rsbRD N-terminal domain HIT PF01230.23 ORY12765.1 - 7.7e-23 81.1 0.2 1.1e-22 80.6 0.2 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 ORY12765.1 - 6.9e-13 49.1 0.0 9.2e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 ORY12765.1 - 0.00024 20.9 0.0 0.00033 20.5 0.0 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CSTF2_hinge PF14327.6 ORY12765.1 - 0.022 15.2 0.0 0.049 14.1 0.0 1.5 2 0 0 2 2 2 0 Hinge domain of cleavage stimulation factor subunit 2 Strep_his_triad PF04270.13 ORY12765.1 - 0.11 12.5 1.3 4.2 7.4 0.0 2.4 2 0 0 2 2 2 0 Streptococcal histidine triad protein N6-adenineMlase PF10237.9 ORY12766.1 - 7.1e-54 181.9 0.5 8.6e-54 181.7 0.5 1.1 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase Cons_hypoth95 PF03602.15 ORY12766.1 - 0.024 14.3 0.1 0.066 12.8 0.0 1.7 1 1 0 2 2 2 0 Conserved hypothetical protein 95 UPF0020 PF01170.18 ORY12766.1 - 0.04 13.6 0.0 0.078 12.7 0.0 1.6 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 BLACT_WH PF17778.1 ORY12767.1 - 8.8e-18 64.0 0.1 1.8e-17 63.0 0.1 1.6 1 0 0 1 1 1 1 Beta-lactamase associated winged helix domain Lactamase_B PF00753.27 ORY12767.1 - 9.1e-18 65.0 1.7 4e-16 59.6 1.7 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 ORY12767.1 - 1.7e-06 27.7 0.6 5.6e-06 26.0 0.6 1.9 1 1 0 1 1 1 1 Beta-lactamase superfamily domain HSP9_HSP12 PF04119.12 ORY12768.1 - 8.6e-26 90.1 6.3 1.1e-25 89.8 5.4 1.6 2 0 0 2 2 2 1 Heat shock protein 9/12 Fig1 PF12351.8 ORY12769.1 - 1.3e-59 201.3 5.2 1.3e-59 201.3 5.2 2.0 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.12 ORY12769.1 - 1.1e-09 38.2 8.1 1.6e-09 37.7 8.1 1.3 1 0 0 1 1 1 1 SUR7/PalI family DUF898 PF05987.13 ORY12769.1 - 0.028 13.5 11.4 0.066 12.3 11.2 1.7 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF898) DUF751 PF05421.11 ORY12769.1 - 0.47 11.2 0.1 0.47 11.2 0.1 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF751) Amastin PF07344.11 ORY12769.1 - 0.66 9.8 9.0 5.2 6.9 5.6 2.3 2 0 0 2 2 2 0 Amastin surface glycoprotein DUF2561 PF10812.8 ORY12769.1 - 1.8 8.6 9.8 14 5.6 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2561) DUF202 PF02656.15 ORY12769.1 - 2.9 8.4 12.1 2.5 8.6 0.1 3.5 2 1 1 3 3 3 0 Domain of unknown function (DUF202) RCC1 PF00415.18 ORY12770.1 - 5.7e-28 97.3 3.8 2e-05 25.1 0.0 7.6 7 1 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 ORY12770.1 - 6.7e-18 64.0 26.0 6.1e-08 32.3 1.0 7.4 7 0 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat Kelch_3 PF13415.6 ORY12770.1 - 0.064 13.6 0.2 0.58 10.5 0.0 2.6 2 1 0 2 2 2 0 Galactose oxidase, central domain Sec34 PF04136.15 ORY12771.1 - 2.9e-52 176.5 1.6 2.9e-52 176.5 1.6 1.7 2 0 0 2 2 2 1 Sec34-like family SHMT PF00464.19 ORY12772.1 - 2e-202 672.1 0.0 2.3e-202 671.9 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.21 ORY12772.1 - 1.2e-05 24.7 0.0 3.5e-05 23.2 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 ORY12772.1 - 0.0022 17.4 0.0 0.0076 15.6 0.0 2.0 1 1 0 1 1 1 1 Beta-eliminating lyase Spc7 PF08317.11 ORY12772.1 - 0.069 12.0 0.1 0.12 11.2 0.1 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein RE_NgoBV PF09564.10 ORY12772.1 - 0.16 11.4 0.0 1.5 8.2 0.0 2.0 2 0 0 2 2 2 0 NgoBV restriction endonuclease Macoilin PF09726.9 ORY12773.1 - 0.38 9.3 12.1 0.52 8.8 12.1 1.2 1 0 0 1 1 1 0 Macoilin family PDCD2_C PF04194.13 ORY12776.1 - 9.2e-47 159.3 0.0 4.4e-45 153.9 0.0 2.4 2 0 0 2 2 2 2 Programmed cell death protein 2, C-terminal putative domain CSN8_PSD8_EIF3K PF10075.9 ORY12777.1 - 8.7e-36 123.0 0.0 1.2e-35 122.5 0.0 1.2 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family SGL PF08450.12 ORY12779.1 - 0.0016 18.1 0.3 0.0054 16.3 0.1 2.0 2 1 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region Holin_2-3 PF13272.6 ORY12779.1 - 0.014 15.7 0.0 0.024 14.9 0.0 1.3 1 0 0 1 1 1 0 Putative 2/3 transmembrane domain holin PLDc_2 PF13091.6 ORY12780.1 - 4.1e-19 68.8 0.1 2.1e-10 40.6 0.0 2.6 2 1 0 2 2 2 2 PLD-like domain PLDc PF00614.22 ORY12780.1 - 7e-05 22.8 0.2 0.022 15.0 0.0 2.8 2 0 0 2 2 2 2 Phospholipase D Active site motif Oxysterol_BP PF01237.18 ORY12782.1 - 9.7e-52 176.0 0.0 9.4e-42 143.2 0.0 2.1 1 1 1 2 2 2 2 Oxysterol-binding protein Peptidase_C2 PF00648.21 ORY12783.1 - 2.6e-26 92.3 0.0 4.3e-26 91.6 0.0 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 ORY12783.1 - 3.2e-07 30.7 0.0 2.5e-06 27.8 0.0 2.4 1 1 0 1 1 1 1 Calpain large subunit, domain III MIT PF04212.18 ORY12783.1 - 0.016 15.3 0.3 0.034 14.2 0.3 1.5 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain DUF1510 PF07423.11 ORY12783.1 - 0.13 12.4 0.2 1.6 9.0 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1510) NRBF2_MIT PF17169.4 ORY12783.1 - 0.14 12.4 0.7 0.37 11.1 0.7 1.6 1 0 0 1 1 1 0 MIT domain of nuclear receptor-binding factor 2 Mito_carr PF00153.27 ORY12784.1 - 1.4e-52 175.5 0.9 5e-20 71.2 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein gag-asp_proteas PF13975.6 ORY12785.1 - 0.00021 21.8 0.0 0.00046 20.7 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 ORY12785.1 - 0.0048 17.5 0.0 0.01 16.5 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Pox_A_type_inc PF04508.12 ORY12786.1 - 0.15 12.0 1.8 0.47 10.4 1.8 1.8 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat LapA_dom PF06305.11 ORY12786.1 - 5.8 6.8 7.0 3.4 7.6 0.2 2.6 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Pkinase PF00069.25 ORY12787.1 - 3.6e-71 239.6 0.0 4.4e-71 239.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY12787.1 - 3.3e-28 98.7 0.0 4.2e-28 98.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY12787.1 - 2.6e-07 30.3 0.0 3.8e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 ORY12787.1 - 0.00018 20.4 0.0 0.0003 19.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 ORY12787.1 - 0.00042 20.3 0.1 0.00075 19.5 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 ORY12787.1 - 0.00054 19.4 0.1 0.00091 18.6 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family iPGM_N PF06415.13 ORY12788.1 - 1.1e-74 250.5 0.0 1.8e-74 249.8 0.0 1.3 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Metalloenzyme PF01676.18 ORY12788.1 - 1.4e-72 244.1 0.1 1.6e-72 243.8 0.1 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 ORY12788.1 - 1.4e-06 28.0 0.0 6.1e-05 22.6 0.0 2.6 2 1 0 2 2 2 1 Sulfatase Phosphodiest PF01663.22 ORY12788.1 - 0.00033 20.4 0.0 0.00052 19.7 0.0 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Alk_phosphatase PF00245.20 ORY12788.1 - 0.00035 19.6 0.1 0.0069 15.4 0.0 2.1 2 0 0 2 2 2 1 Alkaline phosphatase Arm-DNA-bind_2 PF12167.8 ORY12788.1 - 0.064 13.2 0.1 19 5.3 0.1 2.5 2 0 0 2 2 2 0 Arm DNA-binding domain PglZ PF08665.12 ORY12788.1 - 0.075 13.1 0.0 0.2 11.8 0.0 1.7 1 0 0 1 1 1 0 PglZ domain DUF2070 PF09843.9 ORY12799.1 - 0.19 10.0 0.5 0.2 9.9 0.5 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF5079 PF16882.5 ORY12799.1 - 0.22 11.4 1.2 0.33 10.8 1.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5079) Aldo_ket_red PF00248.21 ORY12800.1 - 8.8e-68 228.6 0.1 1.1e-67 228.3 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF5526 PF17664.1 ORY12800.1 - 0.12 12.0 0.0 0.28 10.8 0.0 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5526) ubiquitin PF00240.23 ORY12801.1 - 4.4e-135 439.7 20.4 3.3e-33 113.3 0.6 4.0 4 0 0 4 4 4 4 Ubiquitin family Rad60-SLD PF11976.8 ORY12801.1 - 6.6e-64 211.7 21.0 2e-15 56.4 0.7 4.0 4 0 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 ORY12801.1 - 8.1e-23 80.7 10.7 0.00043 20.7 0.1 5.8 4 4 0 4 4 4 4 Ubiquitin-like domain TBK1_ULD PF18396.1 ORY12801.1 - 1.7e-16 59.9 3.0 0.027 14.4 0.0 4.2 4 0 0 4 4 4 4 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 ORY12801.1 - 3.9e-15 56.0 8.2 0.028 14.8 0.1 4.1 4 0 0 4 4 4 4 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 ORY12801.1 - 2.1e-14 53.6 2.6 0.12 12.4 0.0 5.0 4 4 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 ORY12801.1 - 5.6e-13 49.4 1.4 0.37 11.4 0.0 4.2 1 1 1 4 4 4 4 DUF2407 ubiquitin-like domain Sde2_N_Ubi PF13019.6 ORY12801.1 - 5.2e-11 42.7 0.8 0.52 10.1 0.0 4.1 1 1 3 4 4 4 4 Silencing defective 2 N-terminal ubiquitin domain Ubiquitin_4 PF18036.1 ORY12801.1 - 3.7e-07 30.1 24.0 16 5.6 0.2 8.0 8 0 0 8 8 8 0 Ubiquitin-like domain Methyltrans_RNA PF04452.14 ORY12801.1 - 2.9e-06 26.8 0.4 1.8 7.8 0.0 3.3 3 0 0 3 3 3 3 RNA methyltransferase DUF3861 PF12977.7 ORY12801.1 - 3.8e-06 27.0 2.5 13 6.1 0.0 4.2 4 0 0 4 4 4 0 Domain of Unknown Function with PDB structure (DUF3861) DUF2870 PF11069.8 ORY12801.1 - 7.1e-06 26.3 0.0 30 5.1 0.0 4.6 4 0 0 4 4 4 0 Protein of unknown function (DUF2870) ACT_5 PF13710.6 ORY12801.1 - 1.2e-05 25.0 4.7 10 6.1 0.0 4.3 4 0 0 4 4 4 0 ACT domain Big_7 PF17957.1 ORY12801.1 - 4e-05 24.3 0.1 52 4.7 0.0 4.1 4 0 0 4 4 4 0 Bacterial Ig domain UDP-g_GGTase PF06427.11 ORY12801.1 - 0.00014 21.9 4.3 7.1 6.8 0.0 4.0 4 0 0 4 4 4 0 UDP-glucose:Glycoprotein Glucosyltransferase DUF969 PF06149.12 ORY12801.1 - 0.00042 19.8 0.0 23 4.3 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF969) YcgR_2 PF12945.7 ORY12801.1 - 0.00091 19.3 6.2 29 4.9 0.1 4.3 4 0 0 4 4 4 0 Flagellar protein YcgR DUF493 PF04359.14 ORY12801.1 - 0.003 18.1 0.1 1.4e+02 3.1 0.0 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF493) Raf1_HTH PF18579.1 ORY12801.1 - 0.0037 16.9 0.0 1e+02 2.7 0.0 4.1 4 0 0 4 4 4 0 Rubisco accumulation factor 1 helix turn helix domain ACT_4 PF13291.6 ORY12801.1 - 0.0052 17.4 1.0 1.4e+02 3.1 0.0 4.2 4 0 0 4 4 4 0 ACT domain ORF11CD3 PF10549.9 ORY12801.1 - 0.0068 16.5 0.0 91 3.3 0.0 4.3 4 0 0 4 4 4 0 ORF11CD3 domain ProRS-C_2 PF09181.10 ORY12801.1 - 0.11 12.7 5.8 1.1e+02 3.1 0.1 4.1 4 0 0 4 4 4 0 Prolyl-tRNA synthetase, C-terminal Baculo_p48 PF04878.13 ORY12801.1 - 0.12 11.2 0.0 61 2.4 0.0 3.0 3 0 0 3 3 3 0 Baculovirus P48 protein Tash_PEST PF07708.11 ORY12801.1 - 0.14 12.4 27.2 6.2 7.1 1.4 4.3 4 0 0 4 4 4 0 Tash protein PEST motif Myosin_N PF02736.19 ORY12801.1 - 0.23 11.3 6.3 1.1e+02 2.8 0.0 5.2 4 0 0 4 4 4 0 Myosin N-terminal SH3-like domain HAMP_N3 PF18575.1 ORY12801.1 - 0.23 11.0 1.5 2e+02 1.6 0.0 3.9 4 0 0 4 4 4 0 HAMP N-terminal domain 3 PI3K_p85B PF02192.16 ORY12801.1 - 1.9 8.3 9.3 96 2.8 0.1 4.2 4 0 0 4 4 4 0 PI3-kinase family, p85-binding domain Helo_like_N PF17111.5 ORY12802.1 - 1.5e-05 24.5 0.0 1.9e-05 24.2 0.0 1.0 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins adh_short PF00106.25 ORY12804.1 - 1.3e-38 132.4 0.1 2.4e-38 131.6 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY12804.1 - 7.2e-27 94.5 0.1 1.1e-26 93.9 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY12804.1 - 1.3e-11 44.7 0.7 1.4e-10 41.3 0.7 2.1 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 ORY12804.1 - 4.2e-05 23.1 0.0 8.5e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 ORY12804.1 - 0.00019 20.5 0.1 0.00031 19.9 0.1 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DUF1776 PF08643.10 ORY12804.1 - 0.0026 17.2 0.2 0.0035 16.8 0.2 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) HHH_5 PF14520.6 ORY12804.1 - 0.053 14.1 0.2 6.5 7.4 0.1 2.7 2 0 0 2 2 2 0 Helix-hairpin-helix domain OAM_alpha PF16552.5 ORY12804.1 - 0.11 12.4 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 D-ornithine 4,5-aminomutase alpha-subunit GTP1_OBG PF01018.22 ORY12805.1 - 1.6e-40 138.2 1.5 2e-30 105.4 2.5 2.4 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.23 ORY12805.1 - 2.2e-23 82.5 0.0 3.8e-23 81.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 ORY12805.1 - 6.9e-07 28.9 0.1 1.8e-06 27.6 0.1 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 ORY12805.1 - 0.031 14.2 0.0 0.77 9.6 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase ABC_tran PF00005.27 ORY12805.1 - 0.035 14.6 3.1 0.07 13.7 0.0 2.6 3 0 0 3 3 3 0 ABC transporter MeaB PF03308.16 ORY12805.1 - 0.049 12.6 0.1 1.5 7.7 0.0 2.5 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 ORY12805.1 - 0.07 13.7 0.2 0.22 12.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain GTP_EFTU PF00009.27 ORY12805.1 - 0.075 12.6 0.0 6.4 6.3 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 ORY12805.1 - 0.13 12.3 0.1 1.4 8.9 0.1 2.2 1 1 0 2 2 2 0 Dynamin family Arf PF00025.21 ORY12805.1 - 0.17 11.4 0.0 2.1 7.8 0.0 2.2 2 0 0 2 2 2 0 ADP-ribosylation factor family MCU PF04678.13 ORY12806.1 - 3e-28 99.1 0.6 3e-28 99.1 0.6 1.8 2 0 0 2 2 2 1 Mitochondrial calcium uniporter RRM_1 PF00076.22 ORY12807.1 - 5e-82 269.7 4.0 9.8e-22 76.6 0.1 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 ORY12807.1 - 8.7e-28 96.3 0.3 4.5e-27 94.0 0.2 2.3 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.6 ORY12807.1 - 4.7e-10 39.1 0.6 0.039 13.5 0.0 4.9 3 2 2 5 5 5 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 ORY12807.1 - 4e-05 23.4 0.1 0.025 14.4 0.0 3.6 3 0 0 3 3 3 1 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 ORY12807.1 - 5.4e-05 23.1 0.3 3.5 7.7 0.0 4.7 5 0 0 5 5 5 1 Nup53/35/40-type RNA recognition motif YflT PF11181.8 ORY12807.1 - 0.0011 19.5 3.8 0.96 10.0 0.4 2.9 3 0 0 3 3 3 2 Heat induced stress protein YflT RRM_7 PF16367.5 ORY12807.1 - 0.0015 18.6 0.5 3.8 7.7 0.0 4.8 5 1 0 5 5 5 1 RNA recognition motif OB_RNB PF08206.11 ORY12807.1 - 0.054 13.2 1.5 17 5.2 0.0 3.6 3 0 0 3 3 3 0 Ribonuclease B OB domain DUF1798 PF08807.10 ORY12807.1 - 4.8 7.4 6.4 6.3 7.0 0.5 2.6 2 0 0 2 2 2 0 Bacterial domain of unknown function (DUF1798) FBPase PF00316.20 ORY12809.1 - 8.5e-73 243.9 0.1 1.2e-72 243.4 0.1 1.2 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Inositol_P PF00459.25 ORY12809.1 - 0.082 12.4 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Inositol monophosphatase family DHBP_synthase PF00926.19 ORY12814.1 - 9.7e-79 263.4 0.0 1.2e-78 263.0 0.0 1.1 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase Cu-oxidase_2 PF07731.14 ORY12815.1 - 2.8e-43 146.9 3.3 8.3e-41 138.9 0.1 3.5 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 ORY12815.1 - 1.8e-40 137.7 5.3 1.6e-38 131.4 0.9 3.5 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 ORY12815.1 - 2e-33 115.7 0.1 6.8e-33 114.0 0.1 2.0 1 0 0 1 1 1 1 Multicopper oxidase CLASP_N PF12348.8 ORY12817.1 - 1.1e-07 31.7 0.5 4.7e-06 26.3 0.2 2.4 2 0 0 2 2 2 1 CLASP N terminal HEAT PF02985.22 ORY12817.1 - 1.4e-05 24.9 0.5 5.8 7.5 0.1 5.5 5 0 0 5 5 5 1 HEAT repeat Adaptin_N PF01602.20 ORY12817.1 - 1.5e-05 23.8 1.0 0.00018 20.2 1.0 2.1 1 1 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 ORY12817.1 - 2.5e-05 24.4 0.5 1.3 9.0 0.1 3.1 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 ORY12817.1 - 4.1e-05 23.9 0.5 1.1 9.7 0.0 5.0 3 2 1 4 4 4 1 HEAT repeats Proteasom_PSMB PF10508.9 ORY12817.1 - 0.016 13.7 0.6 0.039 12.5 0.6 1.7 1 0 0 1 1 1 0 Proteasome non-ATPase 26S subunit TAN PF11640.8 ORY12817.1 - 0.021 15.0 1.3 0.1 12.7 1.3 2.2 1 1 0 1 1 1 0 Telomere-length maintenance and DNA damage repair MMS19_N PF14500.6 ORY12817.1 - 0.037 13.6 1.5 1.1 8.8 0.4 2.8 2 1 0 2 2 2 0 Dos2-interacting transcription regulator of RNA-Pol-II p25-alpha PF05517.12 ORY12817.1 - 0.039 14.1 0.3 0.16 12.2 0.0 2.1 2 0 0 2 2 2 0 p25-alpha HEAT_EZ PF13513.6 ORY12817.1 - 0.1 13.1 3.0 7.1 7.3 0.0 4.9 6 1 1 7 7 7 0 HEAT-like repeat GIT_CC PF16559.5 ORY12817.1 - 0.21 11.5 3.3 0.83 9.6 3.3 2.1 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor DivIC PF04977.15 ORY12817.1 - 0.23 11.3 14.9 0.31 10.8 6.5 3.0 1 1 1 2 2 2 0 Septum formation initiator Atg14 PF10186.9 ORY12817.1 - 0.83 8.7 11.5 1.2 8.2 8.8 2.3 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4407 PF14362.6 ORY12817.1 - 0.89 8.9 11.6 0.39 10.0 6.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Cluap1 PF10234.9 ORY12817.1 - 4.7 6.5 15.0 0.84 9.0 8.8 2.4 2 0 0 2 2 2 0 Clusterin-associated protein-1 WD40 PF00400.32 ORY12818.1 - 3.8e-53 176.3 23.6 8.1e-09 36.0 0.8 8.5 8 1 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY12818.1 - 6.4e-14 52.0 0.0 0.00022 21.5 0.0 4.8 4 1 0 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ORY12818.1 - 1.5e-06 27.2 0.0 0.00015 20.6 0.0 3.3 4 0 0 4 4 4 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 ORY12818.1 - 0.00029 19.7 0.0 0.34 9.6 0.0 3.2 3 0 0 3 3 3 2 Nup133 N terminal like bZIP_1 PF00170.21 ORY12818.1 - 0.033 14.3 0.6 0.066 13.3 0.6 1.4 1 0 0 1 1 1 0 bZIP transcription factor Epimerase PF01370.21 ORY12819.1 - 2.5e-06 27.1 0.0 3.5e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family VWA PF00092.28 ORY12820.1 - 0.0044 17.3 0.0 0.0089 16.3 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain UQ_con PF00179.26 ORY12821.1 - 8.2e-09 35.2 0.0 1.5e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 ORY12821.1 - 0.2 12.0 0.1 0.33 11.2 0.1 1.3 1 0 0 1 1 1 0 RWD domain MFS_1 PF07690.16 ORY12824.1 - 1.4e-39 136.1 23.3 1.7e-29 102.8 3.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY12824.1 - 2.4e-11 43.2 0.2 2.4e-11 43.2 0.2 1.5 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.7 ORY12824.1 - 0.0024 16.8 11.7 0.0029 16.5 6.0 2.7 2 1 0 2 2 2 2 MFS_1 like family Fungal_trans PF04082.18 ORY12825.1 - 8.7e-28 97.1 0.0 1.1e-26 93.5 0.0 2.3 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY12825.1 - 4.9e-09 36.2 10.4 7.5e-09 35.6 10.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tyrosinase PF00264.20 ORY12827.1 - 2.5e-47 162.0 0.1 3.5e-47 161.5 0.1 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase MFS_1 PF07690.16 ORY12828.1 - 4.3e-33 114.7 35.9 8.1e-33 113.8 35.9 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 ORY12828.1 - 3e-13 49.1 14.2 4.7e-13 48.4 14.2 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) FAD_binding_3 PF01494.19 ORY12829.1 - 3.7e-12 46.2 0.2 2.5e-11 43.4 0.2 2.3 1 1 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 ORY12829.1 - 9.5e-05 22.4 0.0 0.00091 19.2 0.0 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.24 ORY12829.1 - 0.00021 21.0 0.1 0.00091 18.9 0.0 1.9 2 1 0 2 2 2 1 FAD dependent oxidoreductase SE PF08491.10 ORY12829.1 - 0.029 13.4 0.0 0.05 12.6 0.0 1.4 1 0 0 1 1 1 0 Squalene epoxidase Pyr_redox_2 PF07992.14 ORY12829.1 - 0.067 12.4 0.6 1.2 8.3 0.0 2.4 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORY12829.1 - 0.1 12.9 0.0 0.39 11.0 0.0 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain ADH_N PF08240.12 ORY12830.1 - 1.1e-17 63.8 0.7 6.5e-17 61.4 0.6 2.2 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain HI0933_like PF03486.14 ORY12830.1 - 1.9e-05 23.6 0.0 2.9e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein ADH_zinc_N PF00107.26 ORY12830.1 - 0.00026 21.0 0.0 0.0033 17.4 0.0 2.3 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.6 ORY12830.1 - 0.0026 17.6 0.1 0.0067 16.3 0.1 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated Glu_dehyd_C PF16912.5 ORY12830.1 - 0.062 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus 3HCDH_N PF02737.18 ORY12830.1 - 0.12 12.2 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ProRS-C_1 PF09180.11 ORY12830.1 - 0.12 12.6 0.1 0.27 11.4 0.1 1.6 1 0 0 1 1 1 0 Prolyl-tRNA synthetase, C-terminal Cation_ATPase_C PF00689.21 ORY12831.1 - 1.8e-30 106.0 2.7 2.6e-30 105.5 2.7 1.2 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Cation_ATPase_N PF00690.26 ORY12831.1 - 3.5e-07 29.8 0.0 1.9e-06 27.4 0.0 2.2 2 1 1 3 3 3 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 ORY12831.1 - 0.00031 20.6 1.8 0.00047 20.0 1.8 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ORY12831.1 - 0.0008 19.8 0.2 0.0012 19.1 0.2 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Ycf4 PF02392.16 ORY12831.1 - 0.11 12.0 1.5 0.82 9.2 0.4 2.4 2 0 0 2 2 2 0 Ycf4 Snf7 PF03357.21 ORY12832.1 - 1.1e-46 158.6 11.7 1.3e-46 158.4 11.7 1.0 1 0 0 1 1 1 1 Snf7 CLZ PF16526.5 ORY12832.1 - 0.0031 17.8 8.7 0.0092 16.3 0.0 3.6 2 1 2 4 4 4 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF3584 PF12128.8 ORY12832.1 - 0.0057 14.2 7.9 0.0073 13.9 7.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Atg14 PF10186.9 ORY12832.1 - 0.0059 15.7 4.0 0.0083 15.3 4.0 1.2 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 NPV_P10 PF05531.12 ORY12832.1 - 0.0084 16.5 7.3 0.13 12.8 0.9 2.9 3 1 1 4 4 4 1 Nucleopolyhedrovirus P10 protein MscS_porin PF12795.7 ORY12832.1 - 0.028 13.9 9.0 1.2 8.7 0.1 2.3 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain FlaC_arch PF05377.11 ORY12832.1 - 0.065 13.6 8.7 1.4 9.4 0.0 3.6 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Ca_bind_SSO6904 PF18249.1 ORY12832.1 - 0.082 13.3 0.1 0.14 12.5 0.1 1.5 1 0 0 1 1 1 0 Calcium binding protein SSO6904 Ncstrn_small PF18266.1 ORY12832.1 - 0.12 12.4 0.1 0.17 11.9 0.1 1.2 1 0 0 1 1 1 0 Nicastrin small lobe HSDR_N PF04313.14 ORY12832.1 - 0.12 12.3 1.7 0.11 12.4 0.7 1.4 2 0 0 2 2 1 0 Type I restriction enzyme R protein N terminus (HSDR_N) Exonuc_VII_L PF02601.15 ORY12832.1 - 0.13 11.8 3.7 0.16 11.5 3.7 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit ABC_tran_CTD PF16326.5 ORY12832.1 - 0.17 12.1 0.4 0.17 12.1 0.4 3.3 1 1 2 3 3 3 0 ABC transporter C-terminal domain GrpE PF01025.19 ORY12832.1 - 0.2 11.3 9.7 0.085 12.5 5.9 2.2 1 1 1 2 2 2 0 GrpE FliD_C PF07195.12 ORY12832.1 - 0.23 10.9 0.0 0.23 10.9 0.0 2.4 3 0 0 3 3 3 0 Flagellar hook-associated protein 2 C-terminus DUF848 PF05852.11 ORY12832.1 - 0.31 11.1 8.2 0.24 11.5 4.7 2.3 1 1 2 3 3 3 0 Gammaherpesvirus protein of unknown function (DUF848) FliJ PF02050.16 ORY12832.1 - 0.41 10.9 11.1 0.53 10.5 5.0 2.5 1 1 1 2 2 2 0 Flagellar FliJ protein BORCS7 PF16088.5 ORY12832.1 - 0.46 10.8 5.3 0.4 11.0 2.8 2.2 2 1 0 2 2 2 0 BLOC-1-related complex sub-unit 7 PEP-utilisers_N PF05524.13 ORY12832.1 - 0.47 10.6 4.4 0.8 9.9 0.8 2.3 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal Allexi_40kDa PF05549.11 ORY12832.1 - 0.54 9.7 2.9 3.7 7.0 0.1 2.2 1 1 1 2 2 2 0 Allexivirus 40kDa protein DASH_Spc19 PF08287.11 ORY12832.1 - 1.1 9.2 8.5 7.2 6.5 8.5 2.1 1 1 0 1 1 1 0 Spc19 FapA PF03961.13 ORY12832.1 - 1.1 7.7 11.4 0.64 8.6 3.3 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A Uso1_p115_C PF04871.13 ORY12832.1 - 1.2 9.5 19.9 87 3.5 19.9 2.8 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region TMF_DNA_bd PF12329.8 ORY12832.1 - 2.2 8.4 13.7 1.1 9.3 0.1 3.1 3 1 0 3 3 3 0 TATA element modulatory factor 1 DNA binding Laminin_II PF06009.12 ORY12832.1 - 2.4 8.1 7.8 2 8.4 1.3 2.2 1 1 1 2 2 2 0 Laminin Domain II DUF948 PF06103.11 ORY12832.1 - 3.2 8.1 4.9 4.1 7.7 2.4 2.2 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) SlyX PF04102.12 ORY12832.1 - 4 8.1 13.8 46 4.7 7.3 3.9 1 1 1 3 3 3 0 SlyX APG6_N PF17675.1 ORY12832.1 - 5.7 7.5 16.7 3.5e+03 -1.6 16.8 2.5 1 1 0 1 1 1 0 Apg6 coiled-coil region YabA PF06156.13 ORY12832.1 - 7.1 7.3 10.7 25 5.6 3.5 2.5 1 1 1 2 2 2 0 Initiation control protein YabA SAPS PF04499.15 ORY12833.1 - 1.7e-192 640.6 0.2 1.7e-192 640.6 0.2 2.9 3 1 0 3 3 3 1 SIT4 phosphatase-associated protein Hexapep PF00132.24 ORY12834.1 - 2.5e-07 30.2 17.8 0.018 14.8 1.2 4.6 3 1 2 5 5 5 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 ORY12834.1 - 0.053 13.3 1.2 0.053 13.3 1.2 4.0 3 2 0 3 3 3 0 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 ORY12834.1 - 0.14 11.1 0.2 0.29 10.0 0.2 1.4 1 1 0 1 1 1 0 L-fucokinase Ank_2 PF12796.7 ORY12835.1 - 6.1e-10 39.6 0.0 0.025 15.1 0.0 3.3 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY12835.1 - 3e-09 37.2 0.1 0.039 14.5 0.0 4.5 3 2 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY12835.1 - 2.5e-08 33.5 0.0 0.76 10.5 0.0 5.6 6 0 0 6 6 6 1 Ankyrin repeat Ank_5 PF13857.6 ORY12835.1 - 0.0028 17.9 0.2 89 3.6 0.0 4.9 5 0 0 5 5 5 0 Ankyrin repeats (many copies) Ank PF00023.30 ORY12835.1 - 0.033 14.6 0.0 12 6.5 0.0 4.1 4 1 0 4 4 4 0 Ankyrin repeat DUF2732 PF10809.8 ORY12835.1 - 0.065 13.1 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2732) REPA_OB_2 PF16900.5 ORY12836.1 - 0.022 14.6 0.0 0.04 13.9 0.0 1.3 1 0 0 1 1 1 0 Replication protein A OB domain Suc_Fer-like PF06999.12 ORY12837.1 - 1.1e-71 240.7 0.0 1.4e-71 240.4 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Herpes_DNAp_acc PF04929.12 ORY12839.1 - 0.26 10.2 2.6 0.3 10.0 2.6 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor WLM PF08325.10 ORY12840.1 - 0.089 12.9 0.0 0.091 12.8 0.0 1.2 1 0 0 1 1 1 0 WLM domain MFS_1 PF07690.16 ORY12841.1 - 1.8e-37 129.1 39.3 8.3e-35 120.3 22.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY12841.1 - 4.2e-10 39.1 17.1 4.2e-10 39.1 17.1 2.1 2 1 0 2 2 2 1 Sugar (and other) transporter GST_N_3 PF13417.6 ORY12843.1 - 4e-07 30.3 0.0 7.3e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 ORY12843.1 - 4.7e-06 26.7 0.0 8.1e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 ORY12843.1 - 4.8e-06 26.8 0.0 8.5e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 ORY12843.1 - 0.0015 18.8 0.0 0.0036 17.6 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 ORY12843.1 - 0.0022 18.2 0.0 0.0048 17.1 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 ORY12843.1 - 0.0078 16.2 0.0 0.014 15.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain CorA PF01544.18 ORY12844.1 - 0.00011 21.6 0.1 0.00024 20.5 0.1 1.6 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF2929 PF11151.8 ORY12844.1 - 0.049 13.9 2.8 0.083 13.2 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2929) DUF5337 PF17272.2 ORY12844.1 - 0.49 10.3 2.1 6.1 6.8 0.3 3.0 2 0 0 2 2 2 0 Family of unknown function (DUF5337) MMR_HSR1 PF01926.23 ORY12845.1 - 2.9e-05 24.1 0.0 0.0023 18.0 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ORY12845.1 - 0.0005 20.0 0.5 0.002 18.1 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 ORY12845.1 - 0.0048 17.3 0.1 0.016 15.6 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain Dynamin_N PF00350.23 ORY12845.1 - 0.0081 16.2 0.2 0.062 13.3 0.0 2.4 3 0 0 3 3 3 1 Dynamin family ABC_tran PF00005.27 ORY12845.1 - 0.021 15.3 0.0 0.072 13.6 0.0 2.1 2 0 0 2 2 2 0 ABC transporter IIGP PF05049.13 ORY12845.1 - 0.077 12.0 0.0 0.27 10.3 0.0 1.8 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) Roc PF08477.13 ORY12845.1 - 0.081 13.1 0.2 1.2 9.4 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase ABATE PF07336.11 ORY12845.1 - 0.1 13.3 0.7 0.21 12.2 0.7 1.5 1 0 0 1 1 1 0 Putative stress-induced transcription regulator MeaB PF03308.16 ORY12845.1 - 0.1 11.5 0.0 0.24 10.3 0.0 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AIG1 PF04548.16 ORY12845.1 - 1.3 8.3 4.6 1.8 7.9 0.0 2.8 2 1 1 3 3 3 0 AIG1 family Pro_CA PF00484.19 ORY12846.1 - 1.4e-47 161.9 0.5 1.7e-47 161.6 0.5 1.1 1 0 0 1 1 1 1 Carbonic anhydrase Kinesin PF00225.23 ORY12847.1 - 3.1e-111 371.5 0.3 7e-111 370.3 0.3 1.6 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 ORY12847.1 - 1.6e-26 93.0 0.1 5.3e-26 91.3 0.1 1.9 1 0 0 1 1 1 1 Microtubule binding DUF1398 PF07166.11 ORY12847.1 - 0.093 12.8 0.2 0.38 10.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1398) UQ_con PF00179.26 ORY12848.1 - 2.8e-51 172.8 0.0 3.2e-51 172.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 ORY12848.1 - 0.011 15.5 0.0 0.012 15.3 0.0 1.1 1 0 0 1 1 1 0 Prokaryotic E2 family B RWD PF05773.22 ORY12848.1 - 0.078 13.3 0.0 0.13 12.5 0.0 1.4 1 1 0 1 1 1 0 RWD domain Sulfatase PF00884.23 ORY12849.1 - 2.5e-55 188.1 0.0 3.3e-55 187.7 0.0 1.2 1 0 0 1 1 1 1 Sulfatase Choline_sulf_C PF12411.8 ORY12849.1 - 3.5e-24 84.3 3.9 4.8e-24 83.9 1.5 2.2 1 1 1 2 2 2 1 Choline sulfatase enzyme C terminal Phosphodiest PF01663.22 ORY12849.1 - 4.3e-06 26.6 0.2 7.7e-05 22.4 0.3 2.1 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.6 ORY12849.1 - 0.0053 17.5 0.0 0.012 16.4 0.0 1.6 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase DUF229 PF02995.17 ORY12849.1 - 0.019 13.6 0.0 0.027 13.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) DUF3648 PF12364.8 ORY12849.1 - 0.16 12.2 0.1 0.34 11.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3648) LysM PF01476.20 ORY12851.1 - 2.1e-05 24.5 0.0 0.19 11.9 0.0 2.4 2 0 0 2 2 2 2 LysM domain MSA-2c PF12238.8 ORY12851.1 - 0.026 14.5 3.0 0.036 14.1 3.0 1.2 1 0 0 1 1 1 0 Merozoite surface antigen 2c SSP160 PF06933.11 ORY12851.1 - 9 4.4 14.8 11 4.0 14.8 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DnaJ PF00226.31 ORY12852.1 - 1.9e-23 82.3 2.3 6.4e-23 80.7 2.3 2.0 1 0 0 1 1 1 1 DnaJ domain DUF305 PF03713.13 ORY12852.1 - 0.43 10.7 4.8 0.23 11.6 2.7 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF305) DUF2362 PF10154.9 ORY12852.1 - 1.8 7.4 13.2 3.2 6.6 7.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2362) SIT PF15330.6 ORY12852.1 - 8.9 6.8 5.7 1.3 9.4 0.2 2.5 3 0 0 3 3 3 0 SHP2-interacting transmembrane adaptor protein, SIT Inv-AAD PF18785.1 ORY12853.1 - 5.9e-60 200.8 0.0 6.9e-60 200.6 0.0 1.0 1 0 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase dCMP_cyt_deam_1 PF00383.23 ORY12853.1 - 9.3e-16 57.6 0.0 1.4e-15 57.0 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 ORY12853.1 - 0.0015 18.3 0.0 0.0021 17.8 0.0 1.3 1 1 0 1 1 1 1 MafB19-like deaminase APOBEC_N PF08210.11 ORY12853.1 - 0.0044 16.9 0.0 0.0049 16.8 0.0 1.1 1 0 0 1 1 1 1 APOBEC-like N-terminal domain SnoaL_2 PF12680.7 ORY12854.1 - 3.9e-05 24.2 0.0 5.2e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF2358 PF10184.9 ORY12854.1 - 0.059 13.6 0.0 0.08 13.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2358) Granulin PF00396.18 ORY12855.1 - 2.1 8.7 15.2 5.4 7.4 4.9 2.4 1 1 0 2 2 2 0 Granulin Stn1 PF10451.9 ORY12856.1 - 3.6e-11 42.5 8.1 3.9e-10 39.1 8.1 2.0 1 1 0 1 1 1 1 Telomere regulation protein Stn1 tRNA_anti-codon PF01336.25 ORY12856.1 - 0.0045 17.0 1.6 0.062 13.3 1.6 2.3 1 1 0 1 1 1 1 OB-fold nucleic acid binding domain LptF_LptG PF03739.14 ORY12856.1 - 0.19 10.5 0.6 0.22 10.3 0.6 1.1 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG Rad54_N PF08658.10 ORY12856.1 - 0.68 10.1 6.7 1 9.5 6.7 1.2 1 0 0 1 1 1 0 Rad54 N terminal MMR_HSR1 PF01926.23 ORY12858.1 - 6.6e-16 58.4 0.0 1e-15 57.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 ORY12858.1 - 1.8e-06 28.1 0.1 0.0012 18.9 0.1 2.3 2 0 0 2 2 2 2 Dynamin family RsgA_GTPase PF03193.16 ORY12858.1 - 0.00017 21.6 0.0 0.00051 20.0 0.0 1.8 2 0 0 2 2 2 1 RsgA GTPase FeoB_N PF02421.18 ORY12858.1 - 0.0009 18.8 0.0 0.0044 16.6 0.0 1.9 2 0 0 2 2 2 1 Ferrous iron transport protein B AIG1 PF04548.16 ORY12858.1 - 0.025 13.9 0.0 0.33 10.3 0.1 2.2 2 0 0 2 2 2 0 AIG1 family ABC_tran PF00005.27 ORY12858.1 - 0.051 14.1 0.0 0.15 12.5 0.0 1.7 2 0 0 2 2 2 0 ABC transporter TniB PF05621.11 ORY12858.1 - 0.096 12.1 0.0 0.38 10.1 0.0 2.0 2 1 0 2 2 2 0 Bacterial TniB protein Roc PF08477.13 ORY12858.1 - 0.1 12.8 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 ORY12858.1 - 0.11 12.2 0.0 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain GTP_EFTU PF00009.27 ORY12858.1 - 0.14 11.7 0.0 3.7 7.0 0.0 2.1 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Complex1_LYR_2 PF13233.6 ORY12860.1 - 2.5e-22 79.4 0.0 3.4e-22 79.0 0.0 1.2 1 0 0 1 1 1 1 Complex1_LYR-like DUF1295 PF06966.12 ORY12861.1 - 3.9e-40 137.8 0.2 9.8e-38 130.0 0.2 3.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.16 ORY12861.1 - 0.00093 19.2 0.0 0.0026 17.7 0.0 1.7 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.13 ORY12861.1 - 0.0011 19.3 0.1 0.017 15.5 0.0 2.6 2 1 1 3 3 3 1 Phospholipid methyltransferase ICMT PF04140.14 ORY12861.1 - 0.013 15.9 0.0 0.047 14.1 0.0 2.0 2 0 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Sec3_C PF09763.9 ORY12862.1 - 6.5e-219 728.9 6.6 8.2e-219 728.5 6.6 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.6 ORY12862.1 - 8.6e-29 99.5 0.1 1.6e-28 98.6 0.1 1.5 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Vps52 PF04129.12 ORY12862.1 - 0.001 17.9 0.4 0.002 17.0 0.4 1.4 1 0 0 1 1 1 1 Vps52 / Sac2 family Sec3_C_2 PF15278.6 ORY12862.1 - 0.011 16.1 0.4 0.033 14.5 0.4 1.8 1 0 0 1 1 1 0 Sec3 exocyst complex subunit CCDC-167 PF15188.6 ORY12862.1 - 0.14 12.5 0.1 0.96 9.8 0.1 2.6 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 ABC_tran_CTD PF16326.5 ORY12862.1 - 3.2 8.1 6.9 25 5.2 0.9 3.3 2 0 0 2 2 2 0 ABC transporter C-terminal domain SRP40_C PF05022.12 ORY12863.1 - 3.9e-22 78.9 0.4 3.9e-22 78.9 0.4 2.3 3 0 0 3 3 3 1 SRP40, C-terminal domain Presenilin PF01080.17 ORY12863.1 - 2.8 6.6 12.4 2.7 6.7 12.4 1.1 1 0 0 1 1 1 0 Presenilin Nop14 PF04147.12 ORY12863.1 - 2.8 6.0 15.5 3.5 5.7 15.5 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 ORY12863.1 - 3.2 6.0 15.9 2.9 6.1 15.9 1.1 1 0 0 1 1 1 0 CDC45-like protein FAM176 PF14851.6 ORY12863.1 - 4.6 6.9 17.5 4.4 6.9 0.4 2.1 1 1 1 2 2 2 0 FAM176 family V_ATPase_I PF01496.19 ORY12864.1 - 0 1046.6 0.0 0 1046.4 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family CheZ PF04344.13 ORY12864.1 - 0.0044 17.0 0.6 0.045 13.7 0.0 2.3 2 0 0 2 2 2 1 Chemotaxis phosphatase, CheZ Filament PF00038.21 ORY12864.1 - 0.0074 15.9 1.9 0.88 9.1 0.2 2.2 2 0 0 2 2 2 2 Intermediate filament protein Linker_histone PF00538.19 ORY12864.1 - 0.087 13.2 0.0 0.18 12.2 0.0 1.4 1 0 0 1 1 1 0 linker histone H1 and H5 family Baculo_PEP_C PF04513.12 ORY12864.1 - 0.12 12.4 0.3 1.2 9.2 0.1 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Aminotran_1_2 PF00155.21 ORY12865.1 - 8.3e-35 120.6 0.0 1.6e-34 119.7 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II Sec63 PF02889.16 ORY12866.1 - 6.8e-31 107.4 0.0 1.1e-30 106.7 0.0 1.3 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.29 ORY12866.1 - 2.5e-23 82.7 0.0 4.5e-23 81.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 ORY12866.1 - 2.6e-12 47.1 0.0 5.2e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 ORY12866.1 - 1.3e-05 25.5 0.0 6.1e-05 23.3 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HHH_5 PF14520.6 ORY12866.1 - 7.3e-05 23.3 0.0 0.00035 21.1 0.0 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.9 ORY12866.1 - 0.00049 19.9 0.0 0.0018 18.0 0.0 2.0 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda AAA_30 PF13604.6 ORY12866.1 - 0.00064 19.5 0.0 0.0013 18.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 ORY12866.1 - 0.04 14.2 0.0 0.12 12.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain Helicase_RecD PF05127.14 ORY12866.1 - 0.046 13.6 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Helicase AAA_23 PF13476.6 ORY12866.1 - 0.4 11.2 2.0 2 8.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain Nuc_sug_transp PF04142.15 ORY12867.1 - 1.8e-109 365.7 14.3 2.4e-109 365.3 14.3 1.1 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.11 ORY12867.1 - 1.3e-06 27.9 16.8 6.5e-05 22.3 6.4 2.1 2 0 0 2 2 2 2 UAA transporter family EamA PF00892.20 ORY12867.1 - 1.6e-05 25.1 32.5 5.7e-05 23.3 6.1 2.4 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 ORY12867.1 - 1.7e-05 24.3 19.1 0.012 14.9 9.7 2.2 2 0 0 2 2 2 2 Triose-phosphate Transporter family PUNUT PF16913.5 ORY12867.1 - 0.56 9.4 24.2 0.041 13.1 4.2 2.6 2 2 0 2 2 2 0 Purine nucleobase transmembrane transport PIG-P PF08510.12 ORY12867.1 - 1.5 8.7 7.7 1.5 8.8 0.7 2.9 2 1 0 2 2 2 0 PIG-P TFA2_Winged_2 PF18121.1 ORY12868.1 - 4.4e-18 64.7 0.7 7.4e-18 64.0 0.7 1.4 1 0 0 1 1 1 1 TFA2 Winged helix domain 2 TFIIE_beta PF02186.15 ORY12868.1 - 1.1e-12 48.0 0.2 2.1e-12 47.2 0.2 1.5 1 0 0 1 1 1 1 TFIIE beta subunit core domain FAD_binding_3 PF01494.19 ORY12869.1 - 2.2e-14 53.5 0.1 1.5e-12 47.5 0.1 2.8 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 ORY12869.1 - 0.0004 19.6 0.0 0.034 13.2 0.0 2.7 2 1 0 2 2 2 1 Lycopene cyclase protein SE PF08491.10 ORY12869.1 - 0.00045 19.4 0.0 0.0053 15.8 0.0 2.0 2 0 0 2 2 2 1 Squalene epoxidase DAO PF01266.24 ORY12869.1 - 0.0019 17.9 0.3 0.11 12.1 0.1 2.2 1 1 1 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ORY12869.1 - 0.0034 17.6 0.0 0.007 16.6 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 ORY12869.1 - 0.017 15.1 0.0 0.029 14.4 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 ORY12869.1 - 0.035 13.3 0.0 0.052 12.8 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 ORY12869.1 - 0.096 11.9 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Thi4 family Exonuc_VII_S PF02609.16 ORY12869.1 - 0.1 12.7 0.2 0.24 11.5 0.2 1.6 1 0 0 1 1 1 0 Exonuclease VII small subunit Methyltransf_23 PF13489.6 ORY12870.1 - 5.8e-21 75.0 0.0 7.5e-21 74.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY12870.1 - 7.8e-17 61.7 0.0 1.2e-16 61.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY12870.1 - 1.6e-13 51.2 0.0 2.4e-13 50.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY12870.1 - 2e-13 50.9 0.0 2.9e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY12870.1 - 2.2e-13 50.3 0.0 2.6e-13 50.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 ORY12870.1 - 5.3e-05 22.8 0.0 7.6e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_9 PF08003.11 ORY12870.1 - 0.00027 20.0 0.0 0.00039 19.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) CMAS PF02353.20 ORY12870.1 - 0.022 14.0 0.0 0.2 10.9 0.0 2.0 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase MTS PF05175.14 ORY12870.1 - 0.035 13.7 0.0 0.054 13.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain MRP-L27 PF09809.9 ORY12871.1 - 1.1e-08 34.9 0.4 1.2e-08 34.8 0.4 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 Utp14 PF04615.13 ORY12872.1 - 8.2e-208 692.6 66.0 8.2e-208 692.6 66.0 2.3 1 1 1 2 2 2 1 Utp14 protein Glyoxalase_3 PF13468.6 ORY12873.1 - 4.8e-29 101.7 0.0 7.9e-29 101.0 0.0 1.3 1 1 0 1 1 1 1 Glyoxalase-like domain MFS_1 PF07690.16 ORY12874.1 - 1.1e-24 87.0 27.4 1.3e-24 86.8 27.4 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Pescadillo_N PF06732.11 ORY12874.1 - 0.13 11.8 0.0 0.18 11.4 0.0 1.1 1 0 0 1 1 1 0 Pescadillo N-terminus COX2_TM PF02790.15 ORY12874.1 - 1.4 9.1 5.0 0.5 10.5 1.0 2.2 2 0 0 2 2 2 0 Cytochrome C oxidase subunit II, transmembrane domain Zn_clus PF00172.18 ORY12875.1 - 1.5e-07 31.4 7.9 3.2e-07 30.4 7.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HD-ZIP_N PF04618.12 ORY12876.1 - 0.14 12.6 3.3 0.18 12.3 3.3 1.4 1 1 0 1 1 1 0 HD-ZIP protein N terminus GerPC PF10737.9 ORY12877.1 - 0.082 13.0 3.9 0.13 12.3 3.9 1.3 1 0 0 1 1 1 0 Spore germination protein GerPC COesterase PF00135.28 ORY12878.1 - 6.1e-75 253.0 0.2 1.3e-74 252.0 0.2 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 ORY12878.1 - 6.6e-10 39.2 0.3 2e-09 37.7 0.2 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Dfp1_Him1_M PF08630.10 ORY12879.1 - 5.7e-43 146.2 0.1 2.1e-42 144.3 0.1 2.0 1 0 0 1 1 1 1 Dfp1/Him1, central region zf-DBF PF07535.12 ORY12879.1 - 2.6e-20 72.2 0.1 4.8e-20 71.4 0.1 1.4 1 0 0 1 1 1 1 DBF zinc finger PTCB-BRCT PF12738.7 ORY12879.1 - 0.028 14.4 0.0 0.073 13.0 0.0 1.7 1 0 0 1 1 1 0 twin BRCT domain APG12 PF04110.13 ORY12880.1 - 2.4e-28 98.3 0.0 3.5e-28 97.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.16 ORY12880.1 - 0.033 14.4 0.0 0.042 14.0 0.0 1.2 1 0 0 1 1 1 0 Autophagy protein Atg8 ubiquitin like Pantoate_transf PF02548.15 ORY12881.1 - 8.9e-106 353.0 0.1 1.1e-105 352.8 0.1 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 ORY12881.1 - 1.7e-07 31.0 0.5 2.3e-07 30.5 0.0 1.5 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase DUF4861 PF16153.5 ORY12881.1 - 0.036 13.1 0.0 0.051 12.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4861) UQ_con PF00179.26 ORY12882.1 - 6.5e-37 126.3 0.1 7.8e-37 126.0 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Astro_capsid_p PF12226.8 ORY12882.1 - 0.028 13.6 1.5 0.037 13.2 1.5 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein DNA_pol_phi PF04931.13 ORY12882.1 - 0.31 9.1 2.5 0.33 9.0 2.5 1.0 1 0 0 1 1 1 0 DNA polymerase phi Ank_2 PF12796.7 ORY12883.1 - 3.7e-41 139.6 0.0 6.9e-11 42.6 0.0 4.3 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY12883.1 - 7.6e-27 93.3 0.2 8.7e-09 35.8 0.0 4.7 2 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 ORY12883.1 - 3.1e-24 84.3 0.4 0.0058 17.0 0.0 7.0 6 0 0 6 6 6 6 Ankyrin repeat Ank_3 PF13606.6 ORY12883.1 - 8.8e-21 71.8 0.0 0.052 14.1 0.0 7.3 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 ORY12883.1 - 7.9e-16 57.9 0.9 0.0022 18.3 0.0 6.2 2 2 4 6 6 6 5 Ankyrin repeats (many copies) CorA PF01544.18 ORY12883.1 - 8e-07 28.7 0.4 1.9e-06 27.5 0.4 1.6 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein YukC PF10140.9 ORY12883.1 - 0.035 13.0 0.4 0.056 12.3 0.4 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC DUF2108 PF09881.9 ORY12883.1 - 0.092 12.7 0.6 2.7 8.0 0.4 2.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2108) Sugar_tr PF00083.24 ORY12884.1 - 1.1e-88 298.1 19.4 1.3e-88 297.8 19.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY12884.1 - 1.2e-27 96.8 37.7 3.8e-23 82.0 14.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 ORY12884.1 - 0.0011 17.3 11.8 0.003 15.9 2.4 3.0 2 1 1 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family ABC2_membrane_5 PF13346.6 ORY12884.1 - 0.0017 17.9 8.2 0.0017 17.9 8.2 3.2 4 0 0 4 4 4 1 ABC-2 family transporter protein Neurokinin_B PF03823.14 ORY12884.1 - 0.18 11.8 0.0 0.46 10.5 0.0 1.6 1 0 0 1 1 1 0 Neurokinin B TauD PF02668.16 ORY12885.1 - 1.5e-42 146.3 0.0 2e-42 145.8 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Plasmod_MYXSPDY PF07981.11 ORY12885.1 - 0.13 12.2 0.1 0.25 11.4 0.1 1.4 1 0 0 1 1 1 0 Plasmodium repeat_MYXSPDY PSRT PF07636.11 ORY12886.1 - 1.7 8.4 6.5 17 5.2 2.4 2.8 2 0 0 2 2 2 0 PSRT HECT PF00632.25 ORY12887.1 - 4.3e-70 236.6 0.0 7.2e-70 235.9 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) AZUL PF16558.5 ORY12887.1 - 3.2e-20 72.1 3.4 3.2e-20 72.1 3.4 2.1 2 0 0 2 2 2 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A zf-C2H2_2 PF12756.7 ORY12888.1 - 2.5e-31 108.0 13.5 9.4e-26 90.1 2.1 3.5 3 0 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 ORY12888.1 - 2.4e-08 34.0 7.9 1e-06 28.9 5.3 3.4 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ORY12888.1 - 1.1e-06 28.9 10.4 9.9e-06 25.8 4.0 2.7 2 0 0 2 2 2 2 Zinc-finger of C2H2 type Serglycin PF04360.12 ORY12888.1 - 0.0046 16.9 0.7 0.012 15.5 0.7 1.7 1 0 0 1 1 1 1 Serglycin zf-C2H2 PF00096.26 ORY12888.1 - 0.038 14.5 0.3 0.038 14.5 0.3 4.7 5 0 0 5 5 5 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY12888.1 - 0.11 13.4 17.7 4 8.5 0.1 5.0 4 0 0 4 4 4 0 C2H2-type zinc finger Actin_micro PF17003.5 ORY12888.1 - 0.45 9.6 2.8 2.8 7.0 0.3 2.6 2 1 0 2 2 2 0 Putative actin-like family GAGA PF09237.11 ORY12888.1 - 0.6 10.0 3.2 0.72 9.7 0.4 2.4 2 0 0 2 2 2 0 GAGA factor zf-DBF PF07535.12 ORY12888.1 - 1.4 9.1 5.4 16 5.7 0.9 3.3 2 0 0 2 2 2 0 DBF zinc finger Nudix_N_2 PF14803.6 ORY12888.1 - 2.5 8.1 5.1 9.1 6.3 0.3 3.1 2 0 0 2 2 2 0 Nudix N-terminal 4HBT_3 PF13622.6 ORY12889.1 - 3e-46 158.7 0.3 3.5e-46 158.5 0.3 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 ORY12889.1 - 0.15 12.4 0.0 0.35 11.2 0.0 1.5 1 0 0 1 1 1 0 Thioesterase superfamily Astro_capsid_p PF12226.8 ORY12890.1 - 0.00029 20.1 1.9 0.00037 19.8 1.9 1.1 1 0 0 1 1 1 1 Turkey astrovirus capsid protein Macoilin PF09726.9 ORY12890.1 - 0.12 10.9 3.7 0.2 10.2 3.7 1.2 1 0 0 1 1 1 0 Macoilin family Cellulase PF00150.18 ORY12893.1 - 1.7e-14 54.0 0.0 2e-14 53.7 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Helo_like_N PF17111.5 ORY12913.1 - 3.7e-07 29.7 3.0 1.4e-06 27.8 3.0 1.8 1 1 0 1 1 1 1 Fungal N-terminal domain of STAND proteins Syntaxin-6_N PF09177.11 ORY12913.1 - 0.22 12.1 3.1 2.9 8.5 0.8 2.9 2 2 0 2 2 2 0 Syntaxin 6, N-terminal HET PF06985.11 ORY12914.1 - 4.9e-23 82.1 0.0 9e-23 81.2 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) EthD PF07110.11 ORY12915.1 - 0.0049 18.0 0.0 0.61 11.3 0.0 2.3 2 0 0 2 2 2 2 EthD domain PAC2 PF09754.9 ORY12915.1 - 0.09 12.8 0.0 0.09 12.8 0.0 1.2 1 0 0 1 1 1 0 PAC2 family CNH PF00780.22 ORY12916.1 - 9.6e-78 261.6 0.0 6e-77 259.0 0.0 1.9 2 0 0 2 2 2 1 CNH domain PH_5 PF15405.6 ORY12916.1 - 7e-49 165.4 1.6 7.4e-49 165.3 0.1 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain RhoGEF PF00621.20 ORY12916.1 - 3.9e-39 134.8 1.1 8.2e-39 133.7 1.1 1.6 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.21 ORY12916.1 - 6.7e-15 54.9 0.0 1.6e-14 53.7 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH PF00169.29 ORY12916.1 - 0.047 14.2 0.3 4 8.0 0.0 3.5 3 1 1 4 4 4 0 PH domain KN_motif PF12075.8 ORY12916.1 - 0.062 13.1 0.1 0.21 11.4 0.1 1.9 1 0 0 1 1 1 0 KN motif ATP-synt_C PF00137.21 ORY12917.1 - 1.5e-29 102.1 38.0 2.7e-18 66.0 16.4 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Pkinase PF00069.25 ORY12919.1 - 3.2e-63 213.5 0.0 4.5e-63 213.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY12919.1 - 1.6e-31 109.5 0.0 2.1e-31 109.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 ORY12919.1 - 0.00012 21.1 0.0 0.00016 20.8 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 ORY12919.1 - 0.00061 19.8 0.0 0.046 13.6 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 ORY12919.1 - 0.0038 16.1 0.0 0.0063 15.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Seadorna_VP7 PF07387.11 ORY12919.1 - 0.051 12.6 0.0 0.082 11.9 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Kinase-like PF14531.6 ORY12919.1 - 0.063 12.6 0.0 0.095 12.0 0.0 1.3 1 0 0 1 1 1 0 Kinase-like EST1_DNA_bind PF10373.9 ORY12920.1 - 2.8e-15 56.6 0.1 4.9e-15 55.8 0.1 1.5 1 1 0 1 1 1 1 Est1 DNA/RNA binding domain Response_reg PF00072.24 ORY12924.1 - 4.8e-20 71.8 0.0 7.2e-14 51.9 0.0 2.3 2 0 0 2 2 2 2 Response regulator receiver domain CSN5_C PF18323.1 ORY12924.1 - 1.7 9.6 4.6 0.77 10.7 0.4 2.5 2 0 0 2 2 2 0 Cop9 signalosome subunit 5 C-terminal domain Haspin_kinase PF12330.8 ORY12925.1 - 6.1e-32 111.0 0.0 2.9e-16 59.4 0.0 3.2 3 0 0 3 3 3 3 Haspin like kinase domain acVLRF1 PF18859.1 ORY12925.1 - 0.5 10.7 4.7 1.4 9.2 4.7 1.8 1 0 0 1 1 1 0 Actinobacteria/chloroflexi VLRF1 release factor DUF952 PF06108.12 ORY12926.1 - 7.8e-23 80.3 0.0 1.3e-22 79.6 0.0 1.3 2 0 0 2 2 2 1 Protein of unknown function (DUF952) NUDIX PF00293.28 ORY12929.1 - 7.5e-11 42.2 0.0 1.2e-10 41.5 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain CENP-B_dimeris PF09026.10 ORY12930.1 - 0.019 15.3 1.5 0.024 15.0 1.5 1.1 1 0 0 1 1 1 0 Centromere protein B dimerisation domain FPN1 PF06963.12 ORY12930.1 - 0.031 12.8 0.0 0.035 12.7 0.0 1.1 1 0 0 1 1 1 0 Ferroportin1 (FPN1) FAM176 PF14851.6 ORY12930.1 - 0.055 13.1 2.3 0.083 12.6 2.3 1.3 1 0 0 1 1 1 0 FAM176 family DUF4611 PF15387.6 ORY12930.1 - 0.4 10.9 6.5 0.57 10.4 6.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) DNA_pol_phi PF04931.13 ORY12930.1 - 2.3 6.2 7.5 2.7 6.0 7.5 1.0 1 0 0 1 1 1 0 DNA polymerase phi Radial_spoke PF04712.12 ORY12930.1 - 2.7 6.8 10.3 3.3 6.6 10.3 1.0 1 0 0 1 1 1 0 Radial spokehead-like protein DUF4530 PF15039.6 ORY12930.1 - 3.4 7.9 11.7 5.8 7.1 11.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4530) DUF4637 PF15470.6 ORY12930.1 - 6.7 6.4 10.2 8.9 6.0 10.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Paf1 PF03985.13 ORY12930.1 - 8.6 5.2 11.2 10 5.0 11.2 1.0 1 0 0 1 1 1 0 Paf1 Pkinase PF00069.25 ORY12933.1 - 3.2e-50 171.0 0.0 4.5e-50 170.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY12933.1 - 1.2e-27 96.8 0.0 2.1e-26 92.8 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY12933.1 - 0.0014 18.0 0.1 0.0049 16.2 0.0 1.8 2 0 0 2 2 2 1 Kinase-like PG_binding_3 PF09374.10 ORY12934.1 - 0.076 13.3 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 Predicted Peptidoglycan domain TPR_12 PF13424.6 ORY12937.1 - 7e-38 128.8 27.0 7.5e-16 58.2 3.2 2.9 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.6 ORY12937.1 - 1.1e-30 104.6 11.9 1e-09 37.9 0.7 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 ORY12937.1 - 1.4e-19 69.0 14.5 1.9e-06 27.5 0.5 4.9 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 ORY12937.1 - 2.6e-11 42.7 16.9 0.00019 21.3 0.5 4.9 5 1 1 6 6 5 3 Tetratricopeptide repeat TPR_MalT PF17874.1 ORY12937.1 - 4.8e-11 42.6 8.3 1.5e-06 27.8 1.5 2.0 1 1 1 2 2 2 2 MalT-like TPR region TPR_4 PF07721.14 ORY12937.1 - 1.2e-10 41.0 0.0 0.024 15.2 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 ORY12937.1 - 1.3e-10 40.5 9.9 0.0013 18.6 0.1 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 ORY12937.1 - 2.5e-10 39.7 11.7 0.00086 19.3 0.2 4.1 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 ORY12937.1 - 1.9e-09 37.5 6.9 0.017 15.9 0.2 3.4 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_17 PF13431.6 ORY12937.1 - 4.1e-07 29.9 8.9 0.086 13.3 0.2 4.0 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 ORY12937.1 - 1.2e-06 29.1 15.4 0.0081 16.8 1.3 3.4 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 ORY12937.1 - 1.8e-06 27.5 17.7 0.023 14.4 1.2 5.0 4 1 2 6 6 6 3 TPR repeat RPN7 PF10602.9 ORY12937.1 - 8.3e-06 25.6 2.1 0.045 13.5 0.1 2.8 1 1 2 3 3 3 2 26S proteasome subunit RPN7 TPR_21 PF09976.9 ORY12937.1 - 1.8e-05 24.5 8.9 0.1 12.3 0.4 3.1 1 1 2 3 3 3 2 Tetratricopeptide repeat-like domain PPR PF01535.20 ORY12937.1 - 0.00047 20.2 0.4 3.4 8.1 0.0 3.8 3 0 0 3 3 3 1 PPR repeat SRP68 PF16969.5 ORY12937.1 - 0.0011 18.0 1.3 0.26 10.2 0.2 2.3 1 1 1 2 2 2 2 RNA-binding signal recognition particle 68 DUF4810 PF16068.5 ORY12937.1 - 0.0031 18.0 4.7 4.9 7.8 0.1 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF4810) TPR_19 PF14559.6 ORY12937.1 - 0.0036 17.8 11.3 0.17 12.4 1.2 2.8 1 1 2 3 3 3 3 Tetratricopeptide repeat DUF5113 PF17140.4 ORY12937.1 - 0.014 15.2 4.7 1.5 8.6 0.2 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF5113) DUF2225 PF09986.9 ORY12937.1 - 0.025 14.3 5.0 2 8.1 0.8 2.8 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) DUF4388 PF14332.6 ORY12937.1 - 0.033 14.5 0.0 9 6.6 0.0 3.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4388) DUF630 PF04783.12 ORY12937.1 - 0.09 13.0 1.1 13 6.0 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF630) GBP_C PF02841.14 ORY12937.1 - 0.12 11.8 0.2 2.3 7.6 0.1 2.4 1 1 2 3 3 3 0 Guanylate-binding protein, C-terminal domain RPN6_N PF18055.1 ORY12937.1 - 0.12 12.7 1.4 8.9 6.7 0.2 3.0 2 1 1 3 3 3 0 26S proteasome regulatory subunit RPN6 N-terminal domain FYRN PF05964.14 ORY12937.1 - 0.19 11.6 0.0 40 4.2 0.0 3.0 3 0 0 3 3 3 0 F/Y-rich N-terminus TPR_6 PF13174.6 ORY12937.1 - 0.45 11.3 12.9 0.73 10.6 0.5 3.5 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_3 PF07720.12 ORY12937.1 - 1.5 8.9 6.7 2.4 8.2 0.3 3.3 4 1 0 4 4 3 0 Tetratricopeptide repeat RPN6_C_helix PF18503.1 ORY12937.1 - 2.1 8.1 6.1 23 4.9 0.1 4.3 6 0 0 6 6 6 0 26S proteasome subunit RPN6 C-terminal helix domain BTAD PF03704.17 ORY12937.1 - 3.2 8.2 7.2 14 6.1 0.2 2.6 3 1 0 3 3 2 0 Bacterial transcriptional activator domain MFS_1 PF07690.16 ORY12938.1 - 1.1e-34 120.0 30.3 1.1e-34 120.0 30.3 1.9 1 1 0 2 2 2 1 Major Facilitator Superfamily DUF1682 PF07946.14 ORY12939.1 - 5.7e-108 361.0 1.0 6.6e-108 360.7 1.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) DUF3108 PF11306.8 ORY12939.1 - 0.0076 16.3 0.4 0.99 9.3 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF3108) COX7a PF02238.15 ORY12940.1 - 7.5e-18 64.7 0.4 9e-18 64.4 0.4 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VII Glyco_hydro_18 PF00704.28 ORY12942.1 - 5.6e-72 243.1 0.0 6.8e-72 242.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 ORY12942.1 - 0.00054 20.4 17.2 0.00054 20.4 17.2 2.7 3 0 0 3 3 3 1 Chitin recognition protein Zn_clus PF00172.18 ORY12943.1 - 1.9e-08 34.3 7.8 4.5e-08 33.1 7.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain eIF-5a PF01287.20 ORY12944.1 - 6e-06 26.3 0.2 1.5e-05 25.0 0.2 1.7 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold RCR PF12273.8 ORY12944.1 - 0.56 10.9 9.8 0.096 13.3 4.7 2.3 1 1 1 2 2 2 0 Chitin synthesis regulation, resistance to Congo red 2OG-FeII_Oxy PF03171.20 ORY12945.1 - 8.3e-13 48.7 0.0 3.4e-12 46.7 0.0 2.0 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 ORY12945.1 - 3.3e-10 40.8 0.0 5.9e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal ATP1G1_PLM_MAT8 PF02038.16 ORY12946.1 - 0.17 11.4 3.5 8.8 5.8 0.7 2.6 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family SKG6 PF08693.10 ORY12947.1 - 5.3e-10 38.5 0.1 3.8e-08 32.6 0.0 2.4 2 0 0 2 2 2 2 Transmembrane alpha-helix domain GCK PF07802.11 ORY12947.1 - 0.25 11.8 2.2 0.44 11.0 2.2 1.3 1 0 0 1 1 1 0 GCK domain DUF543 PF04418.12 ORY12947.1 - 0.3 11.1 3.0 4.9 7.2 0.1 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF543) DUF1366 PF07104.11 ORY12948.1 - 0.019 14.6 0.0 0.03 14.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1366) AAA_12 PF13087.6 ORY12949.1 - 3.9e-40 137.6 0.0 6.1e-40 137.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 ORY12949.1 - 4.8e-24 85.6 0.1 2.2e-23 83.4 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 ORY12949.1 - 1e-07 32.4 0.1 1.8e-06 28.3 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 ORY12949.1 - 7.3e-07 29.1 0.0 3.4e-05 23.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 ORY12949.1 - 0.00028 20.7 0.0 0.068 12.9 0.0 3.2 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase DEAD PF00270.29 ORY12949.1 - 0.00035 20.4 0.0 0.00068 19.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 ORY12949.1 - 0.00057 19.9 0.0 0.003 17.6 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit PhoH PF02562.16 ORY12949.1 - 0.00086 18.8 0.0 0.0016 17.9 0.0 1.3 1 0 0 1 1 1 1 PhoH-like protein DUF2075 PF09848.9 ORY12949.1 - 0.0011 18.3 0.2 0.021 14.0 0.0 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) ATPase PF06745.13 ORY12949.1 - 0.074 12.4 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 KaiC WD40 PF00400.32 ORY12950.1 - 1.6e-15 57.2 6.3 0.12 13.3 0.0 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY12950.1 - 0.016 15.4 0.1 16 5.9 0.0 3.3 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Ins_P5_2-kin PF06090.12 ORY12951.1 - 2.5e-50 171.8 0.0 3.1e-50 171.5 0.0 1.1 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase HET PF06985.11 ORY12955.1 - 5.4e-23 82.0 0.0 1e-22 81.0 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HAD_2 PF13419.6 ORY12956.1 - 5.2e-20 72.3 0.0 8.7e-20 71.5 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ORY12956.1 - 5.1e-13 49.8 0.1 1.4e-11 45.1 0.1 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ORY12956.1 - 4.4e-05 23.5 0.0 7.1e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 ORY12956.1 - 0.006 17.0 0.0 0.0083 16.5 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Thiamine_BP PF01910.17 ORY12957.1 - 2e-31 107.7 0.0 2.4e-31 107.5 0.0 1.0 1 0 0 1 1 1 1 Thiamine-binding protein Retro_M PF02813.14 ORY12957.1 - 0.11 12.9 0.0 0.15 12.5 0.0 1.3 1 0 0 1 1 1 0 Retroviral M domain Peptidase_M14 PF00246.24 ORY12959.1 - 3.5e-80 269.9 0.2 6.5e-80 269.0 0.1 1.5 2 0 0 2 2 2 1 Zinc carboxypeptidase Propep_M14 PF02244.16 ORY12959.1 - 4.5e-07 30.2 0.0 1e-06 29.0 0.0 1.6 1 0 0 1 1 1 1 Carboxypeptidase activation peptide P_C PF06640.11 ORY12959.1 - 0.022 14.9 0.2 0.041 14.0 0.2 1.3 1 0 0 1 1 1 0 P protein C-terminus Fungal_trans PF04082.18 ORY12960.1 - 4.1e-07 29.3 0.1 2.5e-06 26.7 0.1 2.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY12960.1 - 1.1e-05 25.4 7.3 2e-05 24.6 7.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HET PF06985.11 ORY12961.1 - 4.1e-08 33.7 0.0 7.3e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) CDH-cyt PF16010.5 ORY12964.1 - 1.7e-19 70.2 0.0 3.1e-19 69.3 0.0 1.3 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase DOMON PF03351.17 ORY12964.1 - 0.00033 20.9 0.0 0.00058 20.1 0.0 1.4 1 0 0 1 1 1 1 DOMON domain DUF3382 PF11862.8 ORY12964.1 - 0.027 14.7 0.0 0.1 12.9 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3382) DUF4079 PF13301.6 ORY12964.1 - 0.29 11.3 8.4 0.58 10.3 2.7 2.8 2 1 0 3 3 3 0 Protein of unknown function (DUF4079) DUF2427 PF10348.9 ORY12964.1 - 4.6 7.1 8.9 0.67 9.8 3.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF2427) DUF1639 PF07797.14 ORY12965.1 - 0.36 10.8 2.7 5.6 7.0 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1639) AA_permease_2 PF13520.6 ORY12966.1 - 3.3e-56 190.9 49.3 4.2e-56 190.6 49.3 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ORY12966.1 - 8.3e-24 84.0 44.2 1.1e-23 83.6 44.2 1.1 1 0 0 1 1 1 1 Amino acid permease Isochorismatase PF00857.20 ORY12967.1 - 1.7e-39 135.8 0.0 2.2e-39 135.4 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family CENP-T_C PF15511.6 ORY12968.1 - 3.3e-09 36.8 0.1 4e-09 36.6 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 ORY12968.1 - 1e-05 25.9 0.2 1.1e-05 25.8 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 ORY12968.1 - 3.2e-05 24.0 0.2 4.6e-05 23.5 0.2 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 ORY12968.1 - 4.9e-05 23.5 0.2 8.5e-05 22.8 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 ORY12968.1 - 0.00013 22.3 0.1 0.00017 21.9 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 ORY12968.1 - 0.0029 17.7 0.0 0.0034 17.4 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 ORY12968.1 - 0.0051 16.8 0.0 0.0069 16.4 0.0 1.3 1 1 0 1 1 1 1 Bromodomain associated UPF0137 PF03677.13 ORY12968.1 - 0.021 14.7 0.2 0.025 14.4 0.2 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) TFIID_20kDa PF03847.13 ORY12968.1 - 0.052 14.0 0.0 0.11 13.0 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A HIGH_NTase1_ass PF16581.5 ORY12968.1 - 0.064 13.2 0.1 0.073 13.0 0.1 1.1 1 0 0 1 1 1 0 Cytidyltransferase-related C-terminal region CbtA PF09490.10 ORY12969.1 - 0.46 10.2 2.4 0.79 9.4 1.8 1.7 1 1 0 1 1 1 0 Probable cobalt transporter subunit (CbtA) SelP_N PF04592.14 ORY12969.1 - 0.52 9.7 11.7 0.76 9.1 11.7 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Peptidase_S9 PF00326.21 ORY12970.1 - 0.001 18.6 0.3 0.0018 17.8 0.3 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 ORY12970.1 - 0.036 13.7 0.4 0.21 11.2 0.5 1.9 1 1 0 1 1 1 0 Putative esterase Abhydrolase_2 PF02230.16 ORY12970.1 - 0.072 12.9 0.4 0.28 10.9 0.1 1.9 1 1 1 2 2 2 0 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 ORY12970.1 - 0.19 11.0 0.5 0.41 9.9 0.1 1.6 1 1 1 2 2 2 0 Serine aminopeptidase, S33 CPSase_L_D2 PF02786.17 ORY12972.1 - 2.6e-71 239.5 0.0 3.9e-71 238.9 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.19 ORY12972.1 - 4.1e-37 126.6 0.0 1.2e-36 125.0 0.0 1.9 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_carb_N PF00289.22 ORY12972.1 - 2.1e-36 124.8 0.0 4.2e-36 123.8 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_lipoyl PF00364.22 ORY12972.1 - 3e-16 59.0 0.7 7.7e-16 57.7 0.7 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 ORY12972.1 - 9.6e-11 41.6 0.0 2e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 ORY12972.1 - 2.8e-08 33.5 0.0 5.4e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 ORY12972.1 - 0.00011 22.3 0.1 0.0003 20.9 0.0 1.8 2 0 0 2 2 2 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 ORY12972.1 - 0.00017 21.4 0.0 0.0043 16.8 0.1 2.4 1 1 1 2 2 2 1 Biotin-lipoyl like GARS_A PF01071.19 ORY12972.1 - 0.016 15.0 0.0 0.026 14.3 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GCV_H PF01597.19 ORY12972.1 - 0.017 15.0 0.3 0.036 13.9 0.3 1.5 1 0 0 1 1 1 0 Glycine cleavage H-protein HlyD_3 PF13437.6 ORY12972.1 - 0.03 15.0 0.0 8.8 7.1 0.0 2.9 2 0 0 2 2 2 0 HlyD family secretion protein L31 PF09784.9 ORY12977.1 - 8.2e-46 154.6 2.1 9.3e-46 154.5 2.1 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 V-SNARE_C PF12352.8 ORY12977.1 - 0.1 12.9 0.1 0.17 12.2 0.1 1.3 1 0 0 1 1 1 0 Snare region anchored in the vesicle membrane C-terminus Sedlin_N PF04628.13 ORY12978.1 - 2.8e-31 108.4 0.0 3.2e-31 108.2 0.0 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region RINGv PF12906.7 ORY12980.1 - 4.4e-17 61.9 7.3 7.9e-17 61.1 7.3 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 ORY12980.1 - 0.00095 19.5 7.6 0.0017 18.6 7.6 1.5 1 0 0 1 1 1 1 Ring finger domain COE1_HLH PF16423.5 ORY12980.1 - 0.078 12.7 0.0 0.34 10.6 0.0 2.0 2 0 0 2 2 2 0 Transcription factor COE1 helix-loop-helix domain zf-ANAPC11 PF12861.7 ORY12980.1 - 0.12 12.4 2.2 0.27 11.3 2.2 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 ORY12980.1 - 1.6 9.0 4.4 3.8 7.7 4.4 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain ArsB PF02040.15 ORY12983.1 - 2.1e-08 34.0 22.5 2.3e-05 23.9 9.7 2.1 2 0 0 2 2 2 2 Arsenical pump membrane protein Dabb PF07876.12 ORY12984.1 - 1.2e-25 90.0 0.1 1.3e-25 89.8 0.1 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain DAO PF01266.24 ORY12986.1 - 4e-47 161.5 0.4 4.7e-47 161.3 0.4 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 ORY12986.1 - 6.2e-05 22.4 0.0 0.00013 21.3 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORY12986.1 - 8.2e-05 22.8 0.1 0.00017 21.7 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ORY12986.1 - 0.00019 20.8 0.3 0.021 14.1 0.0 2.3 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 ORY12986.1 - 0.0027 17.1 0.0 0.0042 16.4 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 ORY12986.1 - 0.0091 16.5 1.3 4 8.1 0.2 3.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 ORY12986.1 - 0.012 14.8 0.0 0.026 13.8 0.0 1.5 1 0 0 1 1 1 0 Thi4 family MCRA PF06100.11 ORY12986.1 - 0.028 13.2 0.4 0.074 11.8 0.0 1.7 2 0 0 2 2 2 0 MCRA family FAD_binding_3 PF01494.19 ORY12986.1 - 0.08 12.2 0.1 0.13 11.4 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain DJ-1_PfpI PF01965.24 ORY12987.1 - 2.3e-16 60.0 0.0 3.1e-16 59.6 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family ACPS PF01648.20 ORY12988.1 - 6.4e-07 29.5 0.3 1.4e-05 25.2 0.3 2.5 1 1 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily SNO PF01174.19 ORY12989.1 - 6.4e-50 169.6 0.0 8.9e-41 139.8 0.0 2.1 1 1 1 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.14 ORY12989.1 - 5.1e-09 36.0 0.0 1.1e-07 31.6 0.0 2.1 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.28 ORY12989.1 - 0.00033 20.5 0.0 0.0013 18.5 0.0 1.8 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_S51 PF03575.17 ORY12989.1 - 0.0014 18.3 0.0 0.003 17.2 0.0 1.5 2 0 0 2 2 2 1 Peptidase family S51 DJ-1_PfpI PF01965.24 ORY12989.1 - 0.073 12.9 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 DJ-1/PfpI family RRM_1 PF00076.22 ORY12990.1 - 2.4e-16 59.3 0.0 3.4e-16 58.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup88 PF10168.9 ORY12991.1 - 1.1e-05 23.5 2.9 0.0012 16.8 1.3 2.5 2 0 0 2 2 2 2 Nuclear pore component CUE PF02845.16 ORY12991.1 - 0.029 14.1 0.1 1.1 9.1 0.2 2.9 3 0 0 3 3 3 0 CUE domain Gp-FAR-1 PF05823.12 ORY12991.1 - 0.36 11.2 1.9 0.72 10.2 0.6 2.2 2 1 0 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DUF1664 PF07889.12 ORY12991.1 - 1.2 9.2 3.0 5.8 7.0 0.5 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DASH_Spc19 PF08287.11 ORY12991.1 - 4.2 7.2 11.2 0.3 11.0 2.8 2.7 2 1 1 3 3 3 0 Spc19 SRR1 PF07985.12 ORY12994.1 - 1.7e-14 53.6 0.0 3.4e-14 52.6 0.0 1.5 1 0 0 1 1 1 1 SRR1 TSCPD PF12637.7 ORY12994.1 - 0.099 12.9 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 TSCPD domain GST_C PF00043.25 ORY12995.1 - 3.9e-17 62.3 0.0 7.9e-17 61.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 ORY12995.1 - 8.2e-13 48.4 0.0 1.7e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 ORY12995.1 - 9.3e-08 32.0 0.0 1.9e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 ORY12995.1 - 2.6e-07 30.9 0.0 4.9e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 ORY12995.1 - 4.8e-07 30.1 0.0 8.9e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 ORY12995.1 - 7.4e-06 26.2 0.0 1.3e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Mistic PF11458.8 ORY12995.1 - 0.34 10.9 1.8 2.3 8.2 0.3 2.3 2 0 0 2 2 2 0 Membrane-integrating protein Mistic MARVEL PF01284.23 ORY12996.1 - 1.1e-05 25.5 13.3 1.4e-05 25.1 12.3 1.7 1 1 1 2 2 2 1 Membrane-associating domain Peptidase_U4 PF03419.13 ORY12996.1 - 2.1 7.6 7.9 1.5 8.1 6.6 1.3 1 1 0 1 1 1 0 Sporulation factor SpoIIGA bZIP_1 PF00170.21 ORY12998.1 - 1.7e-14 53.6 6.8 3.4e-14 52.7 6.8 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 ORY12998.1 - 6.1e-08 32.6 5.3 2.1e-07 30.9 5.3 1.9 1 1 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 ORY12998.1 - 0.00081 19.9 4.0 0.00081 19.9 4.0 2.2 2 0 0 2 2 2 1 bZIP Maf transcription factor Phlebovirus_NSM PF07246.11 ORY12998.1 - 0.0099 15.3 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 1 Phlebovirus nonstructural protein NS-M KR PF08659.10 ORY13011.1 - 1.3e-62 210.9 1.1 4e-62 209.3 0.2 2.3 2 0 0 2 2 2 1 KR domain PS-DH PF14765.6 ORY13011.1 - 4.9e-58 196.7 0.0 1.1e-57 195.6 0.0 1.6 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 ORY13011.1 - 1.9e-35 122.9 1.9 3.5e-35 122.0 1.9 1.4 1 0 0 1 1 1 1 Acyl transferase domain ADH_zinc_N_2 PF13602.6 ORY13011.1 - 6.3e-22 79.1 0.2 9.4e-18 65.5 0.0 3.9 3 0 0 3 3 3 2 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 ORY13011.1 - 2.2e-14 53.6 0.0 8.9e-12 45.1 0.0 3.8 3 0 0 3 3 3 1 Zinc-binding dehydrogenase adh_short PF00106.25 ORY13011.1 - 3.5e-14 52.7 0.2 7.2e-11 41.9 0.0 2.8 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 ORY13011.1 - 1.2e-07 31.6 0.1 3.1e-06 26.9 0.0 2.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase PP-binding PF00550.25 ORY13011.1 - 1.2e-07 32.0 0.0 2.8e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_23 PF13489.6 ORY13011.1 - 3.6e-05 23.7 0.0 0.00029 20.7 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain ADH_N PF08240.12 ORY13011.1 - 0.00023 21.0 3.5 0.00041 20.2 2.4 2.0 2 0 0 2 2 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_12 PF08242.12 ORY13011.1 - 0.011 16.4 0.0 0.053 14.3 0.0 2.2 2 0 0 2 2 1 0 Methyltransferase domain SAT PF16073.5 ORY13011.1 - 0.018 14.8 1.2 0.13 12.0 1.2 2.3 1 1 0 1 1 1 0 Starter unit:ACP transacylase in aflatoxin biosynthesis Methyltransf_11 PF08241.12 ORY13011.1 - 0.053 14.2 0.0 0.31 11.7 0.0 2.4 2 0 0 2 2 1 0 Methyltransferase domain Helicase_C PF00271.31 ORY13013.1 - 0.0015 18.9 0.1 0.0081 16.5 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF776 PF05604.11 ORY13013.1 - 0.014 15.8 0.4 0.03 14.7 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF776) SNF2_N PF00176.23 ORY13014.1 - 1.6e-18 66.6 0.0 2.3e-18 66.1 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain NACHT PF05729.12 ORY13015.1 - 0.0038 17.2 0.1 0.015 15.2 0.1 2.0 1 1 0 1 1 1 1 NACHT domain TagF_N PF09867.9 ORY13015.1 - 0.1 12.6 0.0 0.25 11.3 0.0 1.7 1 0 0 1 1 1 0 TagF N-terminal domain, Type VI secretion system-associated SATase_N PF06426.14 ORY13016.1 - 0.11 12.9 0.0 0.17 12.3 0.0 1.3 1 0 0 1 1 1 0 Serine acetyltransferase, N-terminal Zn_clus PF00172.18 ORY13017.1 - 5.1e-05 23.3 12.6 0.00017 21.6 12.6 2.0 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Homeobox_KN PF05920.11 ORY13018.1 - 6.3e-17 61.2 0.2 1.3e-16 60.2 0.2 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 ORY13018.1 - 9.9e-07 28.5 0.1 2.9e-06 27.0 0.1 1.8 1 0 0 1 1 1 1 Homeodomain HTH_Tnp_Tc5 PF03221.16 ORY13018.1 - 0.0013 18.7 0.0 0.0046 17.0 0.0 2.0 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain zf-C2H2_4 PF13894.6 ORY13018.1 - 0.0029 18.3 2.7 0.0029 18.3 2.7 5.9 6 0 0 6 6 6 1 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 ORY13018.1 - 0.008 16.9 2.0 1.6 9.4 0.1 2.7 2 0 0 2 2 2 2 Zinc finger C2H2-type, 3 repeats zf-C2H2 PF00096.26 ORY13018.1 - 3.1 8.4 29.3 1 10.0 0.4 5.8 6 0 0 6 6 6 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY13018.1 - 4.1 8.0 15.7 0.99 9.9 0.5 4.3 4 0 0 4 4 4 0 Zinc-finger double domain zf-C2H2_2 PF12756.7 ORY13018.1 - 4.1 7.8 10.3 59 4.1 0.0 3.8 1 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) SlyX PF04102.12 ORY13019.1 - 0.14 12.8 2.8 6.3 7.5 0.1 2.7 2 0 0 2 2 2 0 SlyX ZapB PF06005.12 ORY13019.1 - 0.19 12.2 1.0 0.41 11.1 0.1 2.0 2 0 0 2 2 2 0 Cell division protein ZapB F-box-like PF12937.7 ORY13020.1 - 1.2e-05 25.1 1.1 1.2e-05 25.1 1.1 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 ORY13020.1 - 2.8e-05 23.9 1.2 0.00012 21.8 0.8 2.2 2 0 0 2 2 2 1 F-box domain zf-C2H2_jaz PF12171.8 ORY13022.1 - 9.1e-08 32.2 0.3 1.5e-07 31.5 0.3 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ORY13022.1 - 0.00025 21.3 0.8 0.0005 20.4 0.8 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-DBF PF07535.12 ORY13022.1 - 0.0028 17.7 0.3 0.0062 16.6 0.3 1.5 1 0 0 1 1 1 1 DBF zinc finger PPP4R2 PF09184.11 ORY13022.1 - 0.011 15.3 0.8 0.021 14.4 0.1 1.6 2 0 0 2 2 2 0 PPP4R2 zf-C2H2 PF00096.26 ORY13022.1 - 0.18 12.3 0.4 0.45 11.1 0.4 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type Selenoprotein_S PF06936.11 ORY13022.1 - 0.67 9.7 14.5 0.065 13.0 3.9 2.2 2 0 0 2 2 2 0 Selenoprotein S (SelS) GST_N_3 PF13417.6 ORY13023.1 - 1.1e-13 51.4 0.0 2e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 ORY13023.1 - 3.7e-13 49.6 0.0 6.6e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 ORY13023.1 - 3.5e-10 40.1 0.0 7.2e-10 39.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 ORY13023.1 - 0.00075 19.7 0.0 0.0014 18.8 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin GST_C PF00043.25 ORY13023.1 - 0.01 16.1 0.0 0.017 15.3 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 ORY13023.1 - 0.019 15.0 0.0 0.042 13.9 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DNA_topoisoIV PF00521.20 ORY13026.1 - 1.9e-125 419.1 0.1 1.9e-125 419.1 0.1 1.6 2 0 0 2 2 2 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 ORY13026.1 - 1.1e-48 164.7 1.6 3.6e-48 163.1 1.6 2.0 1 0 0 1 1 1 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 ORY13026.1 - 5.3e-26 91.1 4.9 1.3e-25 89.9 4.9 1.6 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 ORY13026.1 - 1.9e-14 54.1 0.1 4.3e-14 53.0 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 ORY13026.1 - 1.4e-06 28.4 0.0 1.2e-05 25.5 0.0 2.7 1 0 0 1 1 1 1 Toprim domain NusA_N PF08529.11 ORY13026.1 - 0.61 10.5 0.0 0.61 10.5 0.0 3.2 3 0 0 3 3 3 0 NusA N-terminal domain Ntox17 PF15524.6 ORY13026.1 - 4.7 7.6 5.5 1.7 9.0 0.3 2.9 4 0 0 4 4 4 0 Novel toxin 17 ADH_zinc_N PF00107.26 ORY13027.1 - 1.1e-21 77.1 0.3 2.8e-21 75.9 0.3 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ORY13027.1 - 4.2e-12 47.3 0.0 7.7e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ORY13027.1 - 6.3e-08 32.5 0.0 1.6e-06 28.0 0.0 2.8 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain PALP PF00291.25 ORY13027.1 - 0.0081 15.6 0.0 0.017 14.6 0.0 1.5 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme Zn_clus PF00172.18 ORY13028.1 - 5.2e-07 29.7 11.9 1.1e-06 28.7 11.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1205 PF06722.12 ORY13028.1 - 0.04 14.0 0.1 0.3 11.2 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1205) Bys1 PF04681.12 ORY13029.1 - 9.2e-05 22.4 0.1 0.00011 22.2 0.1 1.1 1 0 0 1 1 1 1 Blastomyces yeast-phase-specific protein Thiolase_N PF00108.23 ORY13030.1 - 9.9e-89 297.1 1.5 1.3e-88 296.8 1.5 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 ORY13030.1 - 4.3e-37 126.5 1.9 4.4e-36 123.2 0.5 2.5 2 1 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 ORY13030.1 - 6e-06 26.0 7.1 0.00016 21.3 0.6 2.8 2 1 0 3 3 3 2 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 ORY13030.1 - 0.00087 19.1 0.4 0.89 9.4 0.1 2.8 2 0 0 2 2 2 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DUF211 PF02680.14 ORY13030.1 - 0.12 12.5 0.0 0.34 11.1 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized ArCR, COG1888 Sds3 PF08598.11 ORY13031.1 - 1.9e-38 132.7 0.7 2.7e-38 132.2 0.7 1.3 1 0 0 1 1 1 1 Sds3-like Exonuc_VII_L PF02601.15 ORY13031.1 - 0.068 12.7 1.1 0.098 12.2 1.1 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit adh_short PF00106.25 ORY13033.1 - 2.4e-42 144.6 1.2 3.1e-42 144.2 1.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY13033.1 - 9e-30 104.0 0.1 1.3e-29 103.5 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY13033.1 - 3.9e-09 36.7 1.4 9.7e-09 35.4 1.4 1.5 1 1 0 1 1 1 1 KR domain AlaDh_PNT_C PF01262.21 ORY13033.1 - 0.052 12.8 0.5 0.09 12.1 0.5 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NACHT PF05729.12 ORY13035.1 - 3.9e-06 26.9 0.0 1.5e-05 25.0 0.0 2.1 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 ORY13035.1 - 8.1e-05 23.1 0.0 0.0008 19.8 0.0 2.7 3 0 0 3 3 3 1 AAA ATPase domain AAA_18 PF13238.6 ORY13035.1 - 0.0024 18.4 0.0 0.024 15.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 ORY13035.1 - 0.0042 17.4 0.1 0.0099 16.3 0.1 1.6 1 0 0 1 1 1 1 RNA helicase ABC_tran PF00005.27 ORY13035.1 - 0.0053 17.3 0.1 0.023 15.2 0.0 2.1 2 0 0 2 2 2 1 ABC transporter AAA PF00004.29 ORY13035.1 - 0.01 16.3 0.0 0.043 14.3 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 ORY13035.1 - 0.019 14.2 0.0 0.055 12.6 0.0 1.7 1 0 0 1 1 1 0 NB-ARC domain SesA PF17107.5 ORY13035.1 - 0.028 14.6 0.2 0.16 12.2 0.2 2.4 1 1 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases AAA_22 PF13401.6 ORY13035.1 - 0.03 14.6 0.0 0.11 12.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 ORY13035.1 - 0.098 12.6 0.1 0.31 11.0 0.0 1.8 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_23 PF13476.6 ORY13035.1 - 0.47 10.9 5.0 2.2 8.7 0.0 2.6 3 0 0 3 3 3 0 AAA domain Ribosomal_L6e PF01159.19 ORY13036.1 - 1.1e-35 122.5 0.6 1.3e-35 122.3 0.0 1.4 2 0 0 2 2 2 1 Ribosomal protein L6e An_peroxidase PF03098.15 ORY13037.1 - 5.1e-23 81.5 0.0 3.1e-13 49.2 0.1 3.4 1 1 1 2 2 2 2 Animal haem peroxidase Zn_clus PF00172.18 ORY13038.1 - 4e-08 33.2 14.6 6.6e-08 32.6 14.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_25 PF13649.6 ORY13039.1 - 6.5e-13 49.2 0.0 1.2e-12 48.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY13039.1 - 6.6e-13 49.1 0.0 1.5e-12 48.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY13039.1 - 4.8e-09 36.9 0.0 8.7e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY13039.1 - 6.5e-08 32.5 0.0 9.9e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY13039.1 - 4.8e-06 26.5 0.0 1.2e-05 25.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 ORY13039.1 - 0.034 13.5 0.0 0.052 12.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 ORY13039.1 - 0.05 13.1 0.0 0.46 10.0 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase small domain NNMT_PNMT_TEMT PF01234.17 ORY13039.1 - 0.17 11.1 0.1 0.55 9.4 0.0 1.8 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family TcpQ PF10671.9 ORY13040.1 - 0.089 12.9 0.0 0.22 11.7 0.0 1.6 1 0 0 1 1 1 0 Toxin co-regulated pilus biosynthesis protein Q RTA1 PF04479.13 ORY13041.1 - 3.2e-51 173.9 9.3 4.1e-51 173.5 9.3 1.1 1 0 0 1 1 1 1 RTA1 like protein PDR_assoc PF08370.11 ORY13041.1 - 0.005 16.5 0.1 2.4 8.0 0.0 2.7 2 0 0 2 2 2 2 Plant PDR ABC transporter associated NARP1 PF12569.8 ORY13041.1 - 1 8.2 7.2 1.4 7.7 7.2 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 RRF PF01765.19 ORY13042.1 - 6.1e-36 123.8 0.4 8.9e-36 123.3 0.4 1.2 1 0 0 1 1 1 1 Ribosome recycling factor SPX PF03105.19 ORY13044.1 - 1.1 9.0 2.4 1.4 8.8 2.4 1.1 1 0 0 1 1 1 0 SPX domain UQ_con PF00179.26 ORY13045.1 - 1.7e-42 144.4 0.0 1.8e-42 144.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 ORY13045.1 - 0.15 11.8 0.0 0.28 10.9 0.0 1.8 1 1 0 1 1 1 0 Prokaryotic E2 family B Kelch_5 PF13854.6 ORY13046.1 - 2.1e-13 49.9 5.0 6.9e-13 48.3 0.3 3.3 3 0 0 3 3 3 1 Kelch motif Kelch_4 PF13418.6 ORY13046.1 - 0.0044 17.0 7.6 0.33 11.0 0.1 4.5 4 1 1 5 5 5 1 Galactose oxidase, central domain Kelch_3 PF13415.6 ORY13046.1 - 0.0067 16.7 6.2 0.52 10.7 0.1 4.2 4 0 0 4 4 4 1 Galactose oxidase, central domain APG6_N PF17675.1 ORY13046.1 - 0.0071 16.9 5.1 0.013 16.0 5.1 1.3 1 0 0 1 1 1 1 Apg6 coiled-coil region SKG6 PF08693.10 ORY13046.1 - 0.012 15.0 0.1 0.028 13.8 0.1 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF4407 PF14362.6 ORY13046.1 - 0.068 12.5 0.5 0.12 11.7 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Gram_pos_anchor PF00746.21 ORY13046.1 - 0.99 9.4 3.4 2.5 8.1 3.4 1.7 1 0 0 1 1 1 0 LPXTG cell wall anchor motif DEAD PF00270.29 ORY13048.1 - 2e-38 131.9 0.0 1.4e-37 129.2 0.0 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY13048.1 - 2.2e-20 73.1 0.0 5.3e-20 71.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 ORY13048.1 - 4.2e-20 71.7 0.0 7.9e-20 70.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 ORY13048.1 - 0.036 14.1 0.0 0.16 11.9 0.0 2.1 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 ORY13048.1 - 0.27 10.7 5.1 2.3 7.7 0.0 2.1 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain DUF2058 PF09831.9 ORY13048.1 - 0.77 9.9 15.0 1.3 9.2 15.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) DUF4207 PF13904.6 ORY13048.1 - 1.4 8.6 15.9 2 8.0 15.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) Peptidase_C1_2 PF03051.15 ORY13049.1 - 2.5e-154 514.3 0.0 2.9e-154 514.1 0.0 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.23 ORY13049.1 - 6.5e-08 32.9 0.2 0.00036 20.7 0.1 2.4 2 0 0 2 2 2 2 Papain family cysteine protease DUF4296 PF14129.6 ORY13049.1 - 0.01 16.4 0.1 0.026 15.1 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4296) DUF2070 PF09843.9 ORY13050.1 - 0.04 12.2 13.1 0.05 11.9 13.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) TssN PF17555.2 ORY13050.1 - 0.76 9.1 9.6 1 8.7 9.6 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssN CYYR1 PF10873.8 ORY13050.1 - 2 8.9 5.0 0.56 10.7 0.2 1.9 1 1 0 2 2 2 0 Cysteine and tyrosine-rich protein 1 Transket_pyr PF02779.24 ORY13051.1 - 1.7e-62 210.2 0.0 3.4e-62 209.3 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.5 ORY13051.1 - 2.6e-58 196.0 0.1 4.2e-58 195.4 0.1 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal E1_dh PF00676.20 ORY13051.1 - 1.3e-56 191.8 0.0 1.8e-56 191.3 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component 2-oxogl_dehyd_N PF16078.5 ORY13051.1 - 6.7e-19 67.2 1.6 1.6e-18 66.0 1.6 1.7 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus Glyco_hydro_17 PF00332.18 ORY13051.1 - 0.099 12.2 0.1 13 5.3 0.1 2.2 2 0 0 2 2 2 0 Glycosyl hydrolases family 17 BSD PF03909.17 ORY13052.1 - 7.6e-20 70.7 10.0 2e-11 43.7 0.1 3.5 4 0 0 4 4 4 2 BSD domain PH_TFIIH PF08567.11 ORY13052.1 - 1.7e-18 66.7 0.1 3.7e-18 65.7 0.1 1.6 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain Fibrillarin_2 PF10113.9 ORY13052.1 - 0.16 10.6 0.0 0.26 9.9 0.0 1.2 1 0 0 1 1 1 0 Fibrillarin-like archaeal protein DUF1992 PF09350.10 ORY13055.1 - 1.1e-21 76.7 0.1 3.1e-21 75.3 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1992) TRAM_LAG1_CLN8 PF03798.16 ORY13057.1 - 8.7e-50 169.2 9.0 1.2e-49 168.8 9.0 1.2 1 0 0 1 1 1 1 TLC domain DUF2721 PF11026.8 ORY13057.1 - 0.015 15.2 0.8 0.022 14.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) 7tm_6 PF02949.20 ORY13057.1 - 0.023 13.8 1.0 0.034 13.2 1.0 1.3 1 0 0 1 1 1 0 7tm Odorant receptor tRNA-synt_2b PF00587.25 ORY13058.1 - 2.8e-20 73.0 0.0 2.1e-19 70.2 0.0 2.2 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 ORY13058.1 - 4.9e-15 55.7 2.4 1e-14 54.6 2.4 1.6 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain CW_binding_1 PF01473.20 ORY13058.1 - 0.2 12.1 1.8 0.46 10.9 1.8 1.6 1 0 0 1 1 1 0 Putative cell wall binding repeat DivIC PF04977.15 ORY13058.1 - 0.21 11.4 3.6 5.9 6.7 1.1 2.4 2 0 0 2 2 2 0 Septum formation initiator BTB PF00651.31 ORY13059.1 - 0.028 14.7 0.0 0.092 13.0 0.0 1.8 2 0 0 2 2 2 0 BTB/POZ domain adh_short_C2 PF13561.6 ORY13060.1 - 5.9e-54 183.1 0.0 7.5e-54 182.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY13060.1 - 2.1e-42 144.8 0.0 3.4e-42 144.1 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORY13060.1 - 4.3e-12 46.3 0.1 5.7e-12 45.9 0.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ORY13060.1 - 0.042 13.3 0.0 0.08 12.4 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF805 PF05656.14 ORY13060.1 - 0.045 14.2 0.0 0.073 13.5 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF805) Polysacc_synt_2 PF02719.15 ORY13060.1 - 0.051 12.7 0.0 0.085 12.0 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF1776 PF08643.10 ORY13060.1 - 0.15 11.4 0.0 0.21 10.9 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) RCC1 PF00415.18 ORY13061.1 - 9.1e-22 77.4 0.0 1e-06 29.3 0.0 5.5 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 ORY13061.1 - 2.4e-11 43.1 7.9 1.8e-08 34.0 0.1 4.2 4 0 0 4 4 4 2 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 ORY13061.1 - 4.9e-10 39.6 0.0 6.6e-06 26.3 0.0 2.8 2 1 0 2 2 2 2 BTB/POZ domain Ank_4 PF13637.6 ORY13061.1 - 4.3e-09 36.7 0.4 1.6e-08 34.9 0.3 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 ORY13061.1 - 1.3e-06 28.9 0.1 3.3e-06 27.6 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ORY13061.1 - 0.002 18.5 3.4 1.3 9.8 0.1 4.0 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 ORY13061.1 - 0.015 15.6 0.1 3 8.3 0.0 3.3 3 0 0 3 3 3 0 Ankyrin repeats (many copies) ATG13 PF10033.9 ORY13062.1 - 3.1e-66 223.5 0.0 5.8e-66 222.6 0.0 1.5 1 0 0 1 1 1 1 Autophagy-related protein 13 Abhydrolase_2 PF02230.16 ORY13064.1 - 2.1e-05 24.4 0.0 3.3e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Esterase_phd PF10503.9 ORY13064.1 - 0.044 13.3 0.2 0.12 11.9 0.0 1.7 2 0 0 2 2 2 0 Esterase PHB depolymerase ARID PF01388.21 ORY13066.1 - 4.3e-19 69.0 0.1 1.4e-18 67.3 0.0 2.0 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain RFX_DNA_binding PF02257.15 ORY13066.1 - 0.028 15.0 0.0 0.057 14.0 0.0 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain PAXX PF15384.6 ORY13066.1 - 0.058 13.1 0.1 5.3 6.7 0.1 2.7 1 1 0 1 1 1 0 PAXX, PAralog of XRCC4 and XLF, also called C9orf142 DUF4687 PF15747.5 ORY13068.1 - 0.003 18.0 0.4 0.003 18.0 0.4 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4687) HORMA PF02301.18 ORY13070.1 - 2.3e-53 180.9 0.0 4.3e-53 180.1 0.0 1.5 1 0 0 1 1 1 1 HORMA domain PHD PF00628.29 ORY13070.1 - 5.4e-05 23.0 10.8 0.00013 21.7 10.8 1.7 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.6 ORY13070.1 - 0.047 13.6 5.4 0.099 12.6 5.4 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 PHD_2 PF13831.6 ORY13070.1 - 0.063 12.8 3.7 0.16 11.5 3.7 1.8 1 1 0 1 1 1 0 PHD-finger Glycogen_syn PF05693.13 ORY13070.1 - 0.17 10.4 0.0 0.26 9.8 0.0 1.1 1 0 0 1 1 1 0 Glycogen synthase WD40 PF00400.32 ORY13071.1 - 2.2e-40 135.9 17.1 1.6e-05 25.6 0.3 7.7 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.7 ORY13071.1 - 1.1e-08 34.8 0.0 1.9e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY13071.1 - 6.1e-08 32.4 0.0 1.3e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 F-box domain ANAPC4_WD40 PF12894.7 ORY13071.1 - 9.1e-08 32.3 0.9 1.3 9.3 0.0 5.1 2 2 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ORY13071.1 - 0.00022 20.0 2.7 13 4.3 0.1 5.0 5 1 1 6 6 6 3 Nucleoporin Nup120/160 F-box_4 PF15966.5 ORY13071.1 - 0.0023 17.8 0.0 0.0056 16.6 0.0 1.6 1 0 0 1 1 1 1 F-box PQQ_2 PF13360.6 ORY13071.1 - 0.011 15.3 1.4 0.26 10.8 1.4 2.6 1 1 0 1 1 1 0 PQQ-like domain BRAP2 PF07576.12 ORY13072.1 - 1.2e-34 118.5 0.0 1.8e-34 117.9 0.0 1.3 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.19 ORY13072.1 - 1.2e-19 70.4 5.0 2.7e-19 69.3 5.0 1.6 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.6 ORY13072.1 - 3e-08 33.9 8.8 3e-08 33.9 8.8 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 ORY13072.1 - 6.5e-06 25.9 8.2 6.5e-06 25.9 8.2 1.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORY13072.1 - 6.3e-05 22.8 7.3 6.3e-05 22.8 7.3 1.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORY13072.1 - 0.0001 22.2 4.7 0.0006 19.8 4.7 2.3 1 1 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 ORY13072.1 - 0.0002 21.6 6.0 0.00055 20.2 6.0 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 ORY13072.1 - 0.00038 20.1 4.9 0.00038 20.1 4.9 2.6 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 ORY13072.1 - 0.0009 19.1 5.9 0.0009 19.1 5.9 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 ORY13072.1 - 0.0013 18.6 2.2 0.0097 15.8 3.2 1.9 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-RING_5 PF14634.6 ORY13072.1 - 0.0027 17.6 6.5 0.0027 17.6 6.5 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 ORY13072.1 - 0.015 15.3 4.5 0.039 14.0 4.5 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Tropomyosin PF00261.20 ORY13072.1 - 0.14 11.5 18.7 0.22 10.9 18.7 1.2 1 0 0 1 1 1 0 Tropomyosin Fib_alpha PF08702.10 ORY13072.1 - 0.75 10.0 4.6 2.2 8.4 2.4 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family ATG16 PF08614.11 ORY13072.1 - 1.1 9.5 21.5 15 5.8 21.5 2.2 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Tropomyosin_1 PF12718.7 ORY13072.1 - 2 8.6 17.6 5.2 7.2 17.6 1.7 1 1 0 1 1 1 0 Tropomyosin like Zn_ribbon_17 PF17120.5 ORY13072.1 - 3 7.5 13.8 0.092 12.4 5.4 2.3 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 ORY13072.1 - 3.3 7.6 19.4 0.44 10.4 9.3 3.1 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 FUSC PF04632.12 ORY13072.1 - 3.6 6.0 9.5 5.3 5.4 9.5 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Nsp1_C PF05064.13 ORY13072.1 - 5.7 6.8 9.1 27 4.6 2.5 3.0 1 1 1 2 2 2 0 Nsp1-like C-terminal region Drf_GBD PF06371.13 ORY13073.1 - 5.4e-21 75.0 0.3 9.3e-13 48.2 0.0 2.5 2 0 0 2 2 2 2 Diaphanous GTPase-binding Domain Rcd1 PF04078.13 ORY13073.1 - 0.13 11.5 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 Cell differentiation family, Rcd1-like hGDE_central PF14702.6 ORY13073.1 - 0.52 9.9 1.4 0.67 9.6 0.1 1.7 2 0 0 2 2 2 0 Central domain of human glycogen debranching enzyme Stig1 PF04885.13 ORY13074.1 - 7.5e-06 26.5 12.3 7.5e-06 26.5 12.3 3.0 2 1 1 3 3 3 1 Stigma-specific protein, Stig1 Mannosyl_trans2 PF04188.13 ORY13076.1 - 5.9e-51 174.2 17.1 8.4e-51 173.7 17.1 1.2 1 0 0 1 1 1 1 Mannosyltransferase (PIG-V) Ribosomal_L7Ae PF01248.26 ORY13077.1 - 2.7e-21 75.1 0.2 4.1e-21 74.5 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family OCD_Mu_crystall PF02423.15 ORY13078.1 - 4.2e-13 48.9 0.0 5.5e-06 25.6 0.0 3.6 4 0 0 4 4 4 3 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.20 ORY13078.1 - 0.0019 18.2 0.0 0.025 14.6 0.0 2.6 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase BLM10_mid PF16507.5 ORY13079.1 - 1.3e-201 670.9 0.0 4.5e-200 665.8 0.0 2.1 2 0 0 2 2 2 2 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 ORY13079.1 - 3.6e-30 103.7 0.0 6.8e-29 99.6 0.0 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF3437) BLM10_N PF16547.5 ORY13079.1 - 3.7e-20 72.0 0.0 1.3e-19 70.2 0.0 2.1 2 0 0 2 2 2 1 Proteasome-substrate-size regulator, N-terminal CLASP_N PF12348.8 ORY13079.1 - 0.078 12.5 0.1 8.9 5.8 0.0 3.1 3 0 0 3 3 3 0 CLASP N terminal Sld5 PF05916.11 ORY13080.1 - 9.2e-21 74.4 0.0 1.3e-20 73.8 0.0 1.2 1 0 0 1 1 1 1 GINS complex protein Prenyltransf PF01255.19 ORY13082.1 - 7.1e-82 274.3 0.0 1e-81 273.7 0.0 1.2 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase OHCU_decarbox PF09349.10 ORY13082.1 - 0.024 15.1 0.2 0.066 13.7 0.1 1.7 2 0 0 2 2 2 0 OHCU decarboxylase Rib PF08428.10 ORY13082.1 - 0.098 12.7 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Rib/alpha-like repeat DUF3446 PF11928.8 ORY13082.1 - 0.46 10.8 13.2 0.85 10.0 13.1 1.5 1 1 0 1 1 1 0 Early growth response N-terminal domain Glyco_transf_25 PF01755.17 ORY13084.1 - 0.00021 21.2 0.0 0.00066 19.6 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) NeA_P2 PF12312.8 ORY13084.1 - 0.037 13.5 0.0 0.074 12.5 0.0 1.6 1 0 0 1 1 1 0 Nepovirus subgroup A polyprotein 2_5_RNA_ligase2 PF13563.6 ORY13085.1 - 1.7e-14 54.0 0.1 2.1e-14 53.7 0.1 1.1 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily IFT57 PF10498.9 ORY13085.1 - 0.11 11.5 0.5 0.16 10.9 0.5 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 NTP_transferase PF00483.23 ORY13086.1 - 1.5e-54 185.2 0.0 2.9e-54 184.3 0.0 1.4 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep PF00132.24 ORY13086.1 - 8.1e-18 63.4 21.7 1.3e-10 40.6 3.1 4.0 1 1 3 4 4 4 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 ORY13086.1 - 3.6e-11 43.7 0.0 5.1e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 ORY13086.1 - 1.8e-05 24.4 12.7 4.2e-05 23.2 1.5 3.4 3 1 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 ORY13086.1 - 0.00053 18.3 0.2 0.0022 16.2 0.1 1.8 1 1 1 2 2 2 1 Domain of unknown function (DUF4954) CTP_transf_3 PF02348.19 ORY13086.1 - 0.007 16.3 0.0 0.018 15.0 0.0 1.7 2 0 0 2 2 2 1 Cytidylyltransferase IspD PF01128.19 ORY13086.1 - 0.0091 15.7 0.0 0.016 15.0 0.0 1.3 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase KASH_CCD PF14662.6 ORY13087.1 - 0.052 13.4 25.4 1.2 8.9 25.3 2.3 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH FlaC_arch PF05377.11 ORY13087.1 - 0.068 13.6 0.5 0.068 13.6 0.5 3.9 2 1 1 4 4 4 0 Flagella accessory protein C (FlaC) Cnn_1N PF07989.11 ORY13087.1 - 0.11 12.6 26.2 0.04 14.1 11.0 3.5 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 ZapB PF06005.12 ORY13087.1 - 1.2 9.6 33.8 0.037 14.5 3.1 3.7 2 1 2 4 4 4 0 Cell division protein ZapB DUF4407 PF14362.6 ORY13087.1 - 4.5 6.5 13.4 9.3 5.5 13.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Fzo_mitofusin PF04799.13 ORY13087.1 - 5.6 6.5 7.9 0.46 10.0 1.7 2.2 1 1 1 2 2 2 0 fzo-like conserved region Shugoshin_N PF07558.11 ORY13087.1 - 5.7 6.9 13.2 0.81 9.6 2.2 3.5 3 1 0 3 3 3 0 Shugoshin N-terminal coiled-coil region bZIP_1 PF00170.21 ORY13087.1 - 6.3 7.0 32.6 1.3 9.2 3.7 5.2 2 1 3 5 5 5 0 bZIP transcription factor YabA PF06156.13 ORY13087.1 - 7.7 7.2 21.4 0.11 13.2 2.2 3.1 2 1 1 3 3 3 0 Initiation control protein YabA Rhomboid PF01694.22 ORY13088.1 - 0.00094 19.2 0.7 0.0024 17.9 0.7 1.8 1 1 0 1 1 1 1 Rhomboid family DUF1751 PF08551.10 ORY13088.1 - 0.042 14.4 1.9 0.042 14.4 1.9 1.9 1 1 1 2 2 2 0 Eukaryotic integral membrane protein (DUF1751) SET PF00856.28 ORY13089.1 - 7.1e-07 29.8 0.0 1.2e-06 29.0 0.0 1.4 1 0 0 1 1 1 1 SET domain Glyco_hydro_47 PF01532.20 ORY13092.1 - 1.7e-174 581.0 0.0 2e-174 580.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Herpes_UL33 PF03581.13 ORY13092.1 - 0.086 13.2 0.0 0.39 11.1 0.0 2.0 2 0 0 2 2 2 0 Herpesvirus UL33-like protein Glyco_hydro_127 PF07944.12 ORY13092.1 - 0.11 11.0 0.0 4.8 5.5 0.0 2.3 2 1 0 2 2 2 0 Beta-L-arabinofuranosidase, GH127 Band_7 PF01145.25 ORY13093.1 - 0.032 14.2 0.2 0.052 13.5 0.2 1.2 1 0 0 1 1 1 0 SPFH domain / Band 7 family DUF4896 PF16237.5 ORY13093.1 - 0.072 12.9 0.1 0.23 11.3 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4896) Cyclin_N PF00134.23 ORY13094.1 - 2.5e-13 49.9 0.0 4.7e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 ORY13094.1 - 5.3e-09 36.7 0.0 1.1e-08 35.6 0.0 1.6 1 0 0 1 1 1 1 Cyclin Helo_like_N PF17111.5 ORY13095.1 - 0.0084 15.5 0.0 0.01 15.3 0.0 1.1 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins Ank_3 PF13606.6 ORY13096.1 - 0.16 12.6 0.0 1.6 9.6 0.0 2.5 2 0 0 2 2 2 0 Ankyrin repeat Peptidase_S10 PF00450.22 ORY13097.1 - 2e-76 258.1 0.5 3e-76 257.5 0.5 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase GspL_C PF12693.7 ORY13098.1 - 0.053 13.4 1.4 0.1 12.4 1.4 1.5 1 0 0 1 1 1 0 GspL periplasmic domain dsrm PF00035.26 ORY13099.1 - 0.0014 19.3 0.0 0.0026 18.4 0.0 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif DND1_DSRM PF14709.7 ORY13099.1 - 0.098 12.9 0.4 0.28 11.5 0.4 1.8 1 1 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 Dabb PF07876.12 ORY13100.1 - 3.8e-06 27.4 0.0 4.3e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Prenyltrans PF00432.21 ORY13101.1 - 4e-35 119.2 25.0 6.8e-09 35.3 1.5 5.9 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 ORY13101.1 - 0.17 10.9 0.1 7.9 5.5 0.0 2.2 1 1 1 2 2 2 0 Squalene-hopene cyclase N-terminal domain Cupin_2 PF07883.11 ORY13102.1 - 1.6e-06 27.7 0.0 2.6e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Cupin domain MFS_1 PF07690.16 ORY13103.1 - 3e-14 52.7 46.2 3e-14 52.7 46.2 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily GAGBD PF16828.5 ORY13104.1 - 0.32 11.1 5.3 2.4 8.2 5.2 2.0 1 1 0 1 1 1 0 GAG-binding domain on surface antigen DUF1768 PF08719.11 ORY13104.1 - 5.9 7.1 8.4 40 4.4 8.4 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF1768) Aconitase_2_N PF06434.13 ORY13127.1 - 0.096 12.3 1.6 0.18 11.4 0.4 1.7 1 1 1 2 2 2 0 Aconitate hydratase 2 N-terminus Tubulin PF00091.25 ORY13128.1 - 3.3e-68 229.8 0.0 5.2e-68 229.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 ORY13128.1 - 2.5e-45 153.7 0.5 5.8e-45 152.5 0.1 1.8 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 ORY13128.1 - 3.4e-07 30.6 0.1 6.7e-07 29.6 0.1 1.5 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 ORY13128.1 - 0.0036 17.0 0.0 0.012 15.3 0.0 1.8 2 0 0 2 2 2 1 Tubulin domain GDPD PF03009.17 ORY13129.1 - 6.6e-33 114.5 0.0 1.3e-32 113.5 0.0 1.5 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family HET PF06985.11 ORY13130.1 - 1.5e-19 70.8 0.0 2.6e-19 70.0 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Coatomer_E PF04733.14 ORY13131.1 - 1.5e-60 205.0 7.8 1.9e-60 204.7 7.8 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_2 PF07719.17 ORY13131.1 - 1.2e-06 28.2 10.3 0.00047 20.1 0.0 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 ORY13131.1 - 3.2e-06 27.7 10.1 0.0052 17.4 0.8 3.6 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 ORY13131.1 - 6.4e-06 26.6 17.6 0.0059 17.1 4.1 3.7 2 2 1 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 ORY13131.1 - 8.3e-06 25.4 0.4 0.004 16.9 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY13131.1 - 2.4e-05 24.5 0.2 0.56 10.5 0.1 3.5 3 1 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 ORY13131.1 - 2.6e-05 23.8 0.2 0.00097 18.8 0.2 2.9 3 0 0 3 3 3 1 TPR repeat TPR_14 PF13428.6 ORY13131.1 - 0.00036 21.1 16.0 0.017 15.9 0.1 5.2 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_4 PF07721.14 ORY13131.1 - 0.00093 19.6 6.8 0.082 13.6 0.3 3.7 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_15 PF13429.6 ORY13131.1 - 0.0018 17.6 0.6 0.0018 17.6 0.6 2.4 1 1 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 ORY13131.1 - 0.0042 17.3 12.2 0.17 12.2 0.1 4.7 4 2 1 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 ORY13131.1 - 0.0074 16.4 1.8 1 9.8 0.0 3.9 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 ORY13131.1 - 0.018 15.4 0.2 0.54 10.8 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat HemY_N PF07219.13 ORY13131.1 - 0.061 13.5 4.1 19 5.5 0.4 3.4 2 1 1 3 3 3 0 HemY protein N-terminus TPR_9 PF13371.6 ORY13131.1 - 0.11 12.6 0.1 0.11 12.6 0.1 2.9 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 ORY13131.1 - 0.12 12.3 6.7 7.2 6.6 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 ORY13131.1 - 0.14 12.9 8.2 1.4 9.7 0.0 4.9 6 0 0 6 6 5 0 Tetratricopeptide repeat Methyltransf_25 PF13649.6 ORY13132.1 - 3.5e-07 30.8 0.0 7.1e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY13132.1 - 0.00075 20.1 0.0 0.0014 19.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY13132.1 - 0.00091 19.9 0.0 0.0021 18.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY13132.1 - 0.015 15.1 0.0 0.025 14.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DUF695 PF05117.12 ORY13132.1 - 0.13 12.5 0.0 2 8.6 0.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF695) Spermine_synth PF01564.17 ORY13133.1 - 6.7e-70 234.3 0.0 9.7e-70 233.8 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 ORY13133.1 - 2.9e-26 91.1 0.1 4.9e-26 90.4 0.1 1.4 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 ORY13133.1 - 0.00011 22.9 0.0 0.0002 22.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 ORY13133.1 - 0.0089 16.0 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY13133.1 - 0.012 16.4 0.1 0.034 14.9 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain DUF43 PF01861.16 ORY13133.1 - 0.013 14.7 0.0 0.019 14.2 0.0 1.2 1 0 0 1 1 1 0 Branched-chain polyamine synthase A C-terminal domain NAD_kinase PF01513.21 ORY13134.1 - 8.2e-80 268.1 0.0 1.2e-79 267.6 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase Zn_clus PF00172.18 ORY13135.1 - 9.1e-09 35.3 7.9 1.6e-08 34.5 7.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ORY13135.1 - 3.4e-07 29.6 0.1 7.5e-07 28.4 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Aconitase PF00330.20 ORY13136.1 - 1.9e-76 257.9 0.2 2.6e-74 250.9 0.1 2.7 2 1 0 2 2 2 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 ORY13136.1 - 2.8e-13 50.3 0.0 5.7e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain Aconitase_2_N PF06434.13 ORY13136.1 - 0.033 13.8 0.0 0.061 12.9 0.0 1.4 1 0 0 1 1 1 0 Aconitate hydratase 2 N-terminus PEP_mutase PF13714.6 ORY13137.1 - 6.4e-48 163.3 0.3 7.4e-48 163.1 0.3 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 ORY13137.1 - 7.9e-24 84.0 0.6 1.1e-23 83.6 0.6 1.1 1 0 0 1 1 1 1 Isocitrate lyase family AltA1 PF16541.5 ORY13138.1 - 4.5e-08 33.9 0.0 7.7e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Alternaria alternata allergen 1 CENP-F_leu_zip PF10473.9 ORY13140.1 - 0.00061 19.8 82.4 0.018 15.1 17.0 6.7 1 1 6 7 7 7 5 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 betaPIX_CC PF16523.5 ORY13140.1 - 0.0067 16.2 1.0 0.0067 16.2 1.0 6.4 6 1 0 6 6 6 1 betaPIX coiled coil DUF1664 PF07889.12 ORY13140.1 - 0.037 14.1 47.8 0.47 10.5 5.5 7.2 2 1 7 9 9 9 0 Protein of unknown function (DUF1664) DivIC PF04977.15 ORY13140.1 - 0.058 13.2 0.6 0.058 13.2 0.6 9.6 6 3 4 10 10 10 0 Septum formation initiator DASH_Hsk3 PF08227.11 ORY13140.1 - 0.08 13.3 5.2 2.3 8.7 0.1 4.6 3 0 0 3 3 3 0 DASH complex subunit Hsk3 like FlaC_arch PF05377.11 ORY13140.1 - 0.23 11.9 37.9 1.2 9.6 0.4 8.1 6 2 1 7 7 7 0 Flagella accessory protein C (FlaC) Lebercilin PF15619.6 ORY13140.1 - 0.24 11.0 73.1 0.31 10.7 1.7 5.3 3 1 1 4 4 3 0 Ciliary protein causing Leber congenital amaurosis disease Baculo_PEP_C PF04513.12 ORY13140.1 - 0.36 10.9 38.7 0.18 11.8 0.4 5.7 2 1 3 6 6 6 0 Baculovirus polyhedron envelope protein, PEP, C terminus BRE1 PF08647.11 ORY13140.1 - 0.5 10.5 84.3 0.18 11.9 13.1 8.6 3 3 5 8 8 8 0 BRE1 E3 ubiquitin ligase TPR_MLP1_2 PF07926.12 ORY13140.1 - 1.7 8.7 84.9 0.24 11.5 17.0 6.9 2 1 3 6 6 6 0 TPR/MLP1/MLP2-like protein ATG16 PF08614.11 ORY13140.1 - 2.1 8.5 74.5 0.19 11.9 24.5 5.5 1 1 3 5 5 5 0 Autophagy protein 16 (ATG16) MAD PF05557.13 ORY13140.1 - 2.1 6.6 73.0 0.18 10.2 29.6 3.1 1 1 2 3 3 3 0 Mitotic checkpoint protein GAS PF13851.6 ORY13140.1 - 2.9 7.2 78.8 0.057 12.8 20.1 5.6 1 1 5 6 6 5 0 Growth-arrest specific micro-tubule binding TACC_C PF05010.14 ORY13140.1 - 4.9 6.9 64.5 0.73 9.6 13.0 4.8 1 1 2 4 4 4 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Cep57_CLD_2 PF14197.6 ORY13140.1 - 4.9 7.3 54.3 0.54 10.4 2.4 7.9 5 2 2 7 7 7 0 Centrosome localisation domain of PPC89 Tropomyosin PF00261.20 ORY13140.1 - 5.7 6.2 66.1 0.74 9.1 3.1 6.1 2 1 4 7 7 7 0 Tropomyosin Filament PF00038.21 ORY13140.1 - 7.2 6.1 65.0 0.018 14.7 29.7 4.1 1 1 1 3 3 3 0 Intermediate filament protein G-alpha PF00503.20 ORY13141.1 - 8.1e-111 370.6 1.1 9.3e-111 370.4 1.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 ORY13141.1 - 3.2e-15 56.0 0.5 5.9e-10 38.9 0.0 2.6 3 0 0 3 3 3 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 ORY13141.1 - 3.7e-05 23.2 2.9 0.00084 18.7 0.2 2.5 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 ORY13141.1 - 0.031 14.5 0.2 7.2 6.9 0.0 2.8 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase DUF2985 PF11204.8 ORY13141.1 - 0.1 12.7 0.0 0.28 11.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2985) FtsK_SpoIIIE PF01580.18 ORY13141.1 - 0.11 11.9 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_29 PF13555.6 ORY13141.1 - 0.15 11.9 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF1713 PF08213.11 ORY13142.1 - 1.2e-10 41.1 22.3 2.6e-10 40.0 22.3 1.6 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) Pet20 PF08692.10 ORY13142.1 - 0.00096 19.9 0.0 0.0027 18.4 0.0 1.8 1 0 0 1 1 1 1 Mitochondrial protein Pet20 PDE8 PF08629.10 ORY13142.1 - 0.37 10.8 5.2 0.86 9.6 5.2 1.6 1 0 0 1 1 1 0 PDE8 phosphodiesterase Aldo_ket_red PF00248.21 ORY13144.1 - 3.2e-07 29.9 0.0 4e-07 29.5 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Clat_adaptor_s PF01217.20 ORY13145.1 - 9.8e-53 177.9 1.6 1.2e-52 177.7 1.6 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain PulA_N1 PF17999.1 ORY13145.1 - 0.062 14.0 0.0 0.11 13.2 0.0 1.4 1 0 0 1 1 1 0 Pullulanase N1-terminal domain Maf1 PF09174.10 ORY13146.1 - 7e-41 140.3 1.1 8.3e-41 140.0 0.0 1.6 2 0 0 2 2 2 1 Maf1 regulator DUF3915 PF13054.6 ORY13146.1 - 2.4 8.1 4.3 5 7.1 4.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Filament PF00038.21 ORY13148.1 - 0.00038 20.1 19.7 0.00038 20.1 19.7 4.1 1 1 1 3 3 3 1 Intermediate filament protein ATG16 PF08614.11 ORY13148.1 - 0.00051 20.3 21.4 0.00051 20.3 21.4 5.2 2 1 2 4 4 4 1 Autophagy protein 16 (ATG16) KASH_CCD PF14662.6 ORY13148.1 - 0.002 18.0 49.4 0.11 12.3 23.4 3.9 1 1 3 4 4 4 2 Coiled-coil region of CCDC155 or KASH ADIP PF11559.8 ORY13148.1 - 0.0037 17.3 11.6 0.0037 17.3 11.6 5.9 2 1 5 7 7 7 2 Afadin- and alpha -actinin-Binding HAUS-augmin3 PF14932.6 ORY13148.1 - 0.0073 15.9 13.1 0.0073 15.9 13.1 3.9 2 1 2 4 4 4 1 HAUS augmin-like complex subunit 3 SlyX PF04102.12 ORY13148.1 - 0.016 15.8 3.1 0.016 15.8 3.1 6.7 5 1 3 8 8 8 0 SlyX Sugarporin_N PF11471.8 ORY13148.1 - 0.71 9.9 24.2 0.23 11.4 2.2 4.6 4 0 0 4 4 4 0 Maltoporin periplasmic N-terminal extension NPV_P10 PF05531.12 ORY13148.1 - 1.3 9.5 9.1 0.75 10.3 0.7 3.2 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein TSC22 PF01166.18 ORY13148.1 - 5.5 7.4 25.6 6.7 7.1 0.0 6.4 5 2 1 6 6 6 0 TSC-22/dip/bun family MbeD_MobD PF04899.12 ORY13148.1 - 7.9 6.7 17.3 2.6 8.2 0.7 4.6 4 2 1 5 5 5 0 MbeD/MobD like CENP-B_N PF04218.13 ORY13149.1 - 1.9e-07 30.6 5.1 0.37 10.5 0.1 4.1 3 0 0 3 3 3 3 CENP-B N-terminal DNA-binding domain UPF0242 PF06785.11 ORY13149.1 - 1.4e-06 28.6 56.8 0.044 13.9 1.1 7.0 1 1 4 5 5 5 3 Uncharacterised protein family (UPF0242) N-terminus APG6_N PF17675.1 ORY13149.1 - 0.00014 22.4 75.8 0.21 12.1 2.9 7.2 2 2 4 6 6 6 4 Apg6 coiled-coil region Fez1 PF06818.15 ORY13149.1 - 0.00038 21.0 64.9 0.091 13.2 0.7 6.5 1 1 5 6 6 6 3 Fez1 PDR_assoc PF08370.11 ORY13149.1 - 0.0021 17.8 0.0 0.0042 16.8 0.0 1.4 1 0 0 1 1 1 1 Plant PDR ABC transporter associated HTH_3 PF01381.22 ORY13149.1 - 0.04 14.0 8.5 8 6.6 0.1 4.6 4 0 0 4 4 4 0 Helix-turn-helix HTH_26 PF13443.6 ORY13149.1 - 0.044 14.2 18.1 4.3 7.8 0.1 6.3 8 0 0 8 8 7 0 Cro/C1-type HTH DNA-binding domain Alpha-mann_mid PF09261.11 ORY13149.1 - 0.095 12.9 0.1 9.6 6.4 0.1 3.8 4 0 0 4 4 4 0 Alpha mannosidase middle domain CRISPR_Cas2 PF09827.9 ORY13149.1 - 0.2 11.9 3.9 25 5.2 0.1 3.7 3 0 0 3 3 3 0 CRISPR associated protein Cas2 Mga PF05043.13 ORY13149.1 - 0.25 11.9 12.3 20 5.8 0.1 4.8 5 0 0 5 5 5 0 Mga helix-turn-helix domain TMF_TATA_bd PF12325.8 ORY13149.1 - 0.38 11.0 71.9 0.13 12.5 1.0 8.6 6 2 1 8 8 8 0 TATA element modulatory factor 1 TATA binding DUF1582 PF07621.11 ORY13149.1 - 0.46 10.4 4.1 1 9.3 4.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1582) HTH_19 PF12844.7 ORY13149.1 - 0.82 9.7 18.9 13 5.9 0.1 5.9 6 0 0 6 6 6 0 Helix-turn-helix domain Fib_alpha PF08702.10 ORY13149.1 - 0.83 9.8 40.1 1.2 9.3 0.0 7.7 3 2 5 8 8 8 0 Fibrinogen alpha/beta chain family ubiquitin PF00240.23 ORY13150.1 - 6.6e-15 54.6 0.0 9.9e-07 28.4 0.0 3.1 3 0 0 3 3 3 2 Ubiquitin family Rad60-SLD PF11976.8 ORY13150.1 - 4.5e-11 42.4 0.6 1.3e-05 24.9 0.0 2.6 3 0 0 3 3 3 2 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 ORY13150.1 - 0.00035 20.9 0.0 0.018 15.4 0.0 2.5 3 0 0 3 3 3 1 Ubiquitin-like domain Ubiquitin_4 PF18036.1 ORY13150.1 - 0.0046 17.0 0.0 0.19 11.8 0.0 2.3 2 0 0 2 2 2 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 ORY13150.1 - 0.011 15.8 0.0 0.063 13.4 0.0 2.1 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like IBR PF01485.21 ORY13151.1 - 1.1e-10 41.5 41.2 5.8e-09 36.0 7.6 5.6 2 2 3 6 6 6 2 IBR domain, a half RING-finger domain DUF1754 PF08555.10 ORY13153.1 - 4.2e-15 56.3 14.5 7.2e-15 55.6 14.5 1.4 1 0 0 1 1 1 1 Eukaryotic family of unknown function (DUF1754) SR-25 PF10500.9 ORY13153.1 - 0.013 15.1 14.8 0.016 14.8 14.8 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF4551 PF15087.6 ORY13153.1 - 0.058 12.2 5.9 0.062 12.1 5.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) FAM60A PF15396.6 ORY13153.1 - 0.37 10.8 5.1 0.45 10.5 5.1 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Rtf2 PF04641.12 ORY13153.1 - 0.71 9.2 9.9 0.96 8.8 9.9 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger Spore_III_AF PF09581.10 ORY13153.1 - 0.77 9.8 5.0 1.6 8.8 5.0 1.5 1 1 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) SRP-alpha_N PF04086.13 ORY13153.1 - 1.6 8.6 13.6 1.8 8.4 13.6 1.0 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Hid1 PF12722.7 ORY13153.1 - 3 5.8 5.9 3.4 5.7 5.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein MCM3AP_GANP PF16769.5 ORY13153.1 - 6.4 4.9 8.8 8.1 4.6 8.8 1.0 1 0 0 1 1 1 0 MCM3AP domain of GANP Presenilin PF01080.17 ORY13153.1 - 7 5.3 8.0 7.7 5.2 8.0 1.0 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 ORY13153.1 - 7.4 4.7 11.4 8.7 4.5 11.4 1.0 1 0 0 1 1 1 0 CDC45-like protein AA_permease PF00324.21 ORY13157.1 - 5.8e-129 430.8 35.2 7e-129 430.5 35.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ORY13157.1 - 4.8e-33 114.6 39.9 6.6e-33 114.2 39.9 1.1 1 0 0 1 1 1 1 Amino acid permease ATP-synt_8 PF00895.20 ORY13157.1 - 0.43 11.1 2.6 3 8.4 2.6 2.5 1 0 0 1 1 1 0 ATP synthase protein 8 Zn_clus PF00172.18 ORY13158.1 - 8.2e-06 25.9 8.5 1.6e-05 24.9 8.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40_alt PF14077.6 ORY13158.1 - 0.081 12.8 0.8 0.17 11.8 0.8 1.5 1 0 0 1 1 1 0 Alternative WD40 repeat motif Pkinase PF00069.25 ORY13159.1 - 1.3e-31 110.0 0.0 2e-31 109.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY13159.1 - 1.5e-20 73.6 0.0 2.6e-20 72.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase WD40 PF00400.32 ORY13159.1 - 2.6e-18 66.0 2.2 3.3e-08 34.1 0.0 5.6 5 0 0 5 5 5 3 WD domain, G-beta repeat YTH PF04146.15 ORY13159.1 - 6.8e-08 32.6 0.0 0.0041 17.1 0.0 2.4 1 1 1 2 2 2 2 YT521-B-like domain ANAPC4_WD40 PF12894.7 ORY13159.1 - 1.4e-05 25.3 0.0 0.0019 18.5 0.0 3.3 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 ORY13159.1 - 0.00094 18.6 0.4 0.13 11.6 0.0 2.5 2 1 1 3 3 3 2 WD40-like domain PQQ_2 PF13360.6 ORY13159.1 - 0.016 14.8 0.0 0.041 13.5 0.0 1.7 1 0 0 1 1 1 0 PQQ-like domain Nup160 PF11715.8 ORY13159.1 - 0.04 12.6 0.0 0.12 10.9 0.0 1.7 2 0 0 2 2 2 0 Nucleoporin Nup120/160 DHHC PF01529.20 ORY13160.1 - 8.2e-39 132.8 6.1 8.2e-39 132.8 6.1 1.5 2 0 0 2 2 2 1 DHHC palmitoyltransferase DUF3955 PF13127.6 ORY13160.1 - 0.011 15.6 3.9 0.025 14.4 3.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3955) Yip1 PF04893.17 ORY13160.1 - 0.014 15.1 5.8 0.028 14.1 1.2 2.1 2 0 0 2 2 2 0 Yip1 domain DZR PF12773.7 ORY13160.1 - 0.34 11.0 6.8 0.72 9.9 6.8 1.4 1 0 0 1 1 1 0 Double zinc ribbon zinc_ribbon_2 PF13240.6 ORY13160.1 - 2.7 7.8 5.7 5.6 6.8 5.7 1.6 1 0 0 1 1 1 0 zinc-ribbon domain Nterm_IS4 PF13006.7 ORY13161.1 - 0.037 14.2 0.0 0.068 13.4 0.0 1.3 1 0 0 1 1 1 0 Insertion element 4 transposase N-terminal Glyco_transf_25 PF01755.17 ORY13161.1 - 0.24 11.3 0.0 25 4.6 0.0 2.2 2 0 0 2 2 2 0 Glycosyltransferase family 25 (LPS biosynthesis protein) Sugar_tr PF00083.24 ORY13164.1 - 3e-39 135.1 18.1 4.2e-39 134.7 18.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY13164.1 - 2.9e-18 65.9 22.0 3.8e-18 65.5 22.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1616 PF07760.11 ORY13164.1 - 0.049 13.0 0.0 0.086 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1616) Transglut_core PF01841.19 ORY13166.1 - 0.069 13.6 0.0 0.14 12.6 0.0 1.6 1 1 1 2 2 2 0 Transglutaminase-like superfamily Dynamin_N PF00350.23 ORY13167.1 - 5e-16 59.2 0.2 3.4e-15 56.5 0.0 2.3 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 ORY13167.1 - 2.2e-09 37.4 0.0 1.1e-08 35.1 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 ORY13167.1 - 4.2e-06 26.4 1.1 9.8e-05 22.0 0.9 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IIGP PF05049.13 ORY13167.1 - 0.0081 15.3 0.0 0.016 14.3 0.0 1.4 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) DUF2205 PF10224.9 ORY13167.1 - 0.025 14.6 0.1 0.069 13.2 0.1 1.8 1 0 0 1 1 1 0 Short coiled-coil protein Citrate_ly_lig PF08218.11 ORY13167.1 - 0.14 11.9 0.3 0.28 10.9 0.3 1.4 1 0 0 1 1 1 0 Citrate lyase ligase C-terminal domain TsaE PF02367.17 ORY13167.1 - 0.14 12.2 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Snf7 PF03357.21 ORY13168.1 - 2.8e-36 124.7 18.3 3.3e-36 124.5 17.5 1.4 2 0 0 2 2 2 1 Snf7 YlqD PF11068.8 ORY13168.1 - 0.062 13.7 19.1 0.69 10.3 7.1 2.2 1 1 1 2 2 2 0 YlqD protein DUF3958 PF13125.6 ORY13168.1 - 7.2 6.9 14.5 0.25 11.6 4.9 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3958) PP2C PF00481.21 ORY13170.1 - 1.5e-62 211.6 0.5 1.4e-50 172.3 0.8 3.1 2 1 0 2 2 2 2 Protein phosphatase 2C CBS PF00571.28 ORY13171.1 - 5.4e-21 74.8 9.3 2.6e-09 37.4 0.2 4.2 4 0 0 4 4 4 3 CBS domain F-box PF00646.33 ORY13172.1 - 0.00018 21.3 0.3 0.00089 19.1 0.1 2.4 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 ORY13172.1 - 0.019 14.8 0.1 0.052 13.4 0.1 1.8 1 0 0 1 1 1 0 F-box-like Meth_synt_2 PF01717.18 ORY13174.1 - 1.2e-07 31.3 0.0 6.7e-05 22.3 0.0 2.6 2 1 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 ORY13174.1 - 0.1 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Cobalamin-independent synthase, N-terminal domain zf-rbx1 PF12678.7 ORY13176.1 - 3.4e-08 33.6 0.9 6.4e-08 32.8 0.9 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 ORY13176.1 - 3.7e-08 33.6 5.8 1.1e-07 32.1 1.9 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 ORY13176.1 - 3.2e-06 26.9 1.0 5.4e-06 26.2 1.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 ORY13176.1 - 2.8e-05 23.9 1.7 2.8e-05 23.9 1.7 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORY13176.1 - 4.3e-05 23.4 1.7 0.00011 22.1 1.8 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 ORY13176.1 - 0.00016 21.6 2.2 0.00094 19.2 2.2 2.3 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_11 PF17123.5 ORY13176.1 - 0.00032 20.4 5.1 0.0057 16.4 0.4 2.4 2 0 0 2 2 2 2 RING-like zinc finger Zn_ribbon_17 PF17120.5 ORY13176.1 - 0.0017 17.9 0.2 0.0042 16.7 0.2 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 ORY13176.1 - 0.0042 16.9 1.9 0.011 15.6 1.9 1.7 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 ORY13176.1 - 0.023 14.5 1.7 0.023 14.5 1.7 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 ORY13176.1 - 0.067 13.2 0.9 0.18 11.9 0.9 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF2921 PF11145.8 ORY13176.1 - 0.28 8.9 0.3 0.43 8.3 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2921) zf-C3H2C3 PF17122.5 ORY13176.1 - 6.1 7.0 5.7 3.9 7.6 1.6 2.5 2 0 0 2 2 2 0 Zinc-finger Rhomboid PF01694.22 ORY13177.1 - 3.5e-37 127.7 7.7 6.3e-37 126.9 7.7 1.4 1 0 0 1 1 1 1 Rhomboid family DUF1610 PF07754.11 ORY13177.1 - 0.12 12.4 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1610) CD52 PF15116.6 ORY13177.1 - 0.25 11.4 1.0 0.69 10.0 1.0 1.7 1 0 0 1 1 1 0 CAMPATH-1 antigen TMEM43 PF07787.12 ORY13177.1 - 4.4 6.6 5.6 0.6 9.5 0.9 1.8 2 0 0 2 2 2 0 Transmembrane protein 43 zf-C2H2_4 PF13894.6 ORY13178.1 - 4e-09 36.5 30.6 0.015 16.1 0.1 6.7 7 0 0 7 7 7 4 C2H2-type zinc finger zf-C2H2 PF00096.26 ORY13178.1 - 4.4e-08 33.1 23.8 0.004 17.5 0.1 6.4 6 0 0 6 6 6 4 Zinc finger, C2H2 type zf-C2H2_3rep PF18868.1 ORY13178.1 - 0.024 15.3 6.0 0.26 12.0 1.2 3.1 3 0 0 3 3 3 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_jaz PF12171.8 ORY13178.1 - 0.028 14.7 16.5 1.6 9.1 0.0 5.8 6 0 0 6 6 6 0 Zinc-finger double-stranded RNA-binding zinc_ribbon_15 PF17032.5 ORY13178.1 - 0.25 12.1 18.1 4.9 8.0 2.1 3.4 3 0 0 3 3 3 0 zinc-ribbon family zf-TFIIB PF13453.6 ORY13178.1 - 0.66 9.4 5.8 0.19 11.1 0.3 2.7 2 0 0 2 2 2 0 Transcription factor zinc-finger zf-C2H2_2 PF12756.7 ORY13178.1 - 1.7 9.0 24.2 1.3 9.4 0.5 4.1 2 2 2 4 4 4 0 C2H2 type zinc-finger (2 copies) IBR PF01485.21 ORY13178.1 - 6.2 7.1 22.2 5.5 7.3 7.4 3.8 2 1 1 3 3 3 0 IBR domain, a half RING-finger domain zf-CSL PF05207.13 ORY13178.1 - 6.8 6.5 7.9 1.3 8.8 0.1 3.0 3 0 0 3 3 3 0 CSL zinc finger Cyanate_lyase PF02560.14 ORY13179.1 - 6.4e-33 112.4 0.0 9.3e-33 111.9 0.0 1.2 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain HTH_3 PF01381.22 ORY13179.1 - 0.0033 17.4 0.1 0.0063 16.5 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix Sigma70_r4_2 PF08281.12 ORY13179.1 - 0.18 11.5 0.0 0.35 10.6 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 PLDc_2 PF13091.6 ORY13180.1 - 1.7e-15 57.1 0.0 4.2e-06 26.7 0.0 4.3 3 1 0 3 3 3 3 PLD-like domain PLDc PF00614.22 ORY13180.1 - 1.3e-12 47.3 0.4 5.3e-05 23.2 0.0 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif DUF3431 PF11913.8 ORY13181.1 - 4.4e-86 288.1 0.0 5.5e-86 287.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) F-box PF00646.33 ORY13182.1 - 4.4e-07 29.6 2.7 5.7e-07 29.3 1.1 2.1 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 ORY13182.1 - 0.00012 21.9 0.6 0.00028 20.7 0.6 1.6 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 ORY13182.1 - 0.048 13.6 0.0 0.091 12.6 0.0 1.5 1 0 0 1 1 1 0 F-box KTI12 PF08433.10 ORY13185.1 - 1.9e-87 293.2 0.0 2.3e-87 292.9 0.0 1.0 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_16 PF13191.6 ORY13185.1 - 0.034 14.5 0.0 0.053 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 ORY13185.1 - 0.06 13.5 0.0 0.21 11.8 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 ORY13185.1 - 0.08 13.5 0.0 0.23 12.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain CPT PF07931.12 ORY13185.1 - 0.12 12.3 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Fungal_trans PF04082.18 ORY13188.1 - 1e-34 119.8 0.2 1.6e-34 119.2 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY13188.1 - 1.7e-09 37.6 10.9 3.1e-09 36.8 10.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain bZIP_1 PF00170.21 ORY13188.1 - 0.15 12.2 0.1 0.15 12.2 0.1 1.7 2 0 0 2 2 2 0 bZIP transcription factor SET PF00856.28 ORY13189.1 - 6.4e-06 26.7 0.0 1.2e-05 25.7 0.0 1.5 1 1 0 1 1 1 1 SET domain DSPn PF14671.6 ORY13190.1 - 3.7e-41 140.9 0.0 4.5e-39 134.1 0.0 2.4 2 0 0 2 2 2 2 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 ORY13190.1 - 2.1e-15 56.7 0.0 4e-15 55.8 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 ORY13190.1 - 3.5e-06 26.8 0.0 6.9e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase GAF_2 PF13185.6 ORY13191.1 - 4.6e-11 43.2 0.0 6.5e-11 42.7 0.0 1.4 1 1 0 1 1 1 1 GAF domain GAF PF01590.26 ORY13191.1 - 5.6e-05 23.8 0.0 8.3e-05 23.2 0.0 1.3 1 1 0 1 1 1 1 GAF domain Hexapep PF00132.24 ORY13192.1 - 2.9e-12 45.8 10.6 3e-06 26.7 0.7 5.0 4 1 1 5 5 5 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 ORY13192.1 - 1.8e-07 30.8 4.0 0.0094 15.7 0.1 3.9 4 0 0 4 4 4 2 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 ORY13192.1 - 0.022 13.7 0.3 0.026 13.4 0.3 1.1 1 0 0 1 1 1 0 L-fucokinase RSN1_7TM PF02714.15 ORY13193.1 - 2e-80 270.0 26.1 2e-80 270.0 26.1 1.8 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 ORY13193.1 - 1e-25 91.0 8.2 1.2e-15 58.2 0.1 2.9 2 1 0 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 ORY13193.1 - 2.2e-23 82.7 5.5 2.2e-23 82.7 5.5 4.3 5 1 0 5 5 5 1 Late exocytosis, associated with Golgi transport PHM7_ext PF12621.8 ORY13193.1 - 4.1e-14 52.5 0.1 1.2e-13 51.0 0.1 1.8 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter Macoilin PF09726.9 ORY13193.1 - 0.026 13.1 15.8 0.17 10.4 1.6 2.2 2 0 0 2 2 2 0 Macoilin family PBP_N PF17093.5 ORY13193.1 - 0.18 12.0 4.5 0.67 10.2 4.5 2.0 1 0 0 1 1 1 0 Penicillin-binding protein N-terminus Methyltransf_16 PF10294.9 ORY13195.1 - 3.2e-17 62.8 0.0 4.2e-17 62.4 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 ORY13195.1 - 0.0014 18.5 0.0 0.0021 17.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY13195.1 - 0.07 13.9 0.0 0.17 12.6 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 ORY13195.1 - 0.075 12.2 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family Copper-fist PF00649.18 ORY13196.1 - 2.2e-16 59.1 3.6 7.4e-16 57.4 3.6 2.0 1 0 0 1 1 1 1 Copper fist DNA binding domain SUN PF03856.13 ORY13198.1 - 2.7e-79 266.1 10.5 3.5e-79 265.7 10.5 1.1 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) GFO_IDH_MocA PF01408.22 ORY13199.1 - 2.4e-23 83.2 0.0 4.7e-23 82.3 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.17 ORY13199.1 - 0.0064 17.0 0.1 0.028 15.0 0.0 2.1 2 1 1 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent Semialdhyde_dh PF01118.24 ORY13199.1 - 0.11 12.9 0.1 0.34 11.3 0.0 1.8 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Glutaredoxin2_C PF04399.13 ORY13202.1 - 0.049 13.5 0.0 0.82 9.5 0.0 2.2 2 0 0 2 2 2 0 Glutaredoxin 2, C terminal domain SRPRB PF09439.10 ORY13203.1 - 0.11 12.0 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit zf-met PF12874.7 ORY13203.1 - 0.73 10.3 5.1 4.3 7.9 0.0 3.0 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Pex24p PF06398.11 ORY13204.1 - 1.1e-91 307.6 0.0 1.3e-91 307.3 0.0 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF3292 PF11696.8 ORY13204.1 - 0.0011 17.4 0.7 0.0028 16.1 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3292) DASH_Dam1 PF08653.10 ORY13204.1 - 0.033 14.0 1.1 0.11 12.3 1.1 1.8 1 1 0 1 1 1 0 DASH complex subunit Dam1 DUF639 PF04842.12 ORY13204.1 - 0.1 12.0 0.2 0.18 11.2 0.2 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF639) Pkinase PF00069.25 ORY13207.1 - 8e-53 179.5 0.1 1.4e-52 178.6 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY13207.1 - 1.6e-19 70.2 0.2 3.5e-19 69.1 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 ORY13207.1 - 0.025 14.5 0.8 0.044 13.7 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 ORY13207.1 - 0.1 12.1 0.2 0.22 11.1 0.2 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase ABC1 PF03109.16 ORY13207.1 - 0.15 12.2 0.0 0.36 11.0 0.0 1.6 1 0 0 1 1 1 0 ABC1 family MAGP PF05507.11 ORY13208.1 - 0.064 13.7 0.0 0.1 13.0 0.0 1.3 1 0 0 1 1 1 0 Microfibril-associated glycoprotein (MAGP) IDO PF01231.18 ORY13209.1 - 1.4e-165 551.3 0.0 1.6e-165 551.1 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase CsbD PF05532.12 ORY13210.1 - 5.9e-09 35.7 20.9 1.5e-07 31.2 8.2 3.2 2 1 1 3 3 3 3 CsbD-like Pmp3 PF01679.17 ORY13211.1 - 2e-24 85.5 8.1 2.2e-24 85.4 8.1 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator CNOT11 PF10155.9 ORY13212.1 - 4.8e-11 42.9 0.0 1.1e-10 41.7 0.0 1.6 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 11 Egh16-like PF11327.8 ORY13213.1 - 6.6e-72 241.8 12.3 2e-71 240.2 12.3 1.7 1 1 0 1 1 1 1 Egh16-like virulence factor Syntaxin PF00804.25 ORY13214.1 - 1.7e-18 67.0 1.9 1.7e-18 67.0 1.9 1.5 2 0 0 2 2 2 1 Syntaxin SNARE PF05739.19 ORY13214.1 - 1.1e-07 31.7 1.3 1.1e-07 31.7 1.3 2.0 2 0 0 2 2 2 1 SNARE domain Syntaxin_2 PF14523.6 ORY13214.1 - 0.0025 18.1 4.8 0.0025 18.1 4.8 2.1 2 0 0 2 2 2 1 Syntaxin-like protein Use1 PF09753.9 ORY13214.1 - 0.0027 17.5 3.2 0.0041 16.9 3.2 1.3 1 0 0 1 1 1 1 Membrane fusion protein Use1 DUF2207 PF09972.9 ORY13214.1 - 0.014 14.2 0.1 0.014 14.2 0.1 1.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Orf78 PF06024.12 ORY13214.1 - 0.021 15.1 0.1 0.058 13.7 0.1 1.7 1 0 0 1 1 1 0 Orf78 (ac78) LAP1C PF05609.12 ORY13214.1 - 0.023 13.8 2.6 0.03 13.4 2.6 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) ETRAMP PF09716.10 ORY13214.1 - 0.027 14.5 0.0 0.033 14.2 0.0 1.3 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Synaptobrevin PF00957.21 ORY13214.1 - 0.034 13.9 1.5 0.052 13.3 0.3 1.9 2 0 0 2 2 2 0 Synaptobrevin TMEM156 PF15106.6 ORY13214.1 - 0.068 12.6 0.3 0.11 11.9 0.0 1.5 2 0 0 2 2 2 0 TMEM156 protein family PBP1_TM PF14812.6 ORY13214.1 - 0.096 13.1 0.4 0.28 11.6 0.0 1.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sigma_1_2 PF03084.14 ORY13214.1 - 0.098 11.9 0.4 0.16 11.2 0.4 1.4 1 0 0 1 1 1 0 Reoviral Sigma1/Sigma2 family V_ATPase_I PF01496.19 ORY13214.1 - 0.13 10.2 1.1 0.16 9.8 1.1 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CENP-F_leu_zip PF10473.9 ORY13214.1 - 0.13 12.3 5.9 0.19 11.7 0.9 2.6 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4094 PF13334.6 ORY13214.1 - 2.2 8.8 4.0 5.3 7.5 0.0 3.0 3 1 0 4 4 3 0 Domain of unknown function (DUF4094) Mod_r PF07200.13 ORY13214.1 - 8.9 6.4 11.7 1.6 8.8 3.3 2.3 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Glyco_hydro_72 PF03198.14 ORY13215.1 - 2.8e-135 450.6 1.3 3.8e-135 450.2 1.3 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 ORY13215.1 - 0.00026 20.5 0.1 0.0063 16.0 0.1 2.4 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) MMR_HSR1_C PF08438.10 ORY13216.1 - 2.5e-36 124.7 0.0 4.2e-36 123.9 0.0 1.4 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.23 ORY13216.1 - 4e-20 72.0 0.0 2.3e-19 69.5 0.0 2.2 1 1 1 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 ORY13216.1 - 3.8e-09 36.2 0.2 1.7e-07 30.9 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 ORY13216.1 - 0.00057 19.5 0.0 0.074 12.6 0.0 2.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 ORY13216.1 - 0.038 13.9 1.2 0.76 9.7 0.1 2.2 2 0 0 2 2 2 0 RsgA GTPase Dynamin_N PF00350.23 ORY13216.1 - 0.041 14.0 1.4 0.15 12.1 0.3 2.2 2 0 0 2 2 2 0 Dynamin family ABC_tran PF00005.27 ORY13216.1 - 0.048 14.2 0.0 0.79 10.2 0.0 2.2 2 0 0 2 2 2 0 ABC transporter HTH_27 PF13463.6 ORY13216.1 - 0.062 13.8 0.0 0.34 11.4 0.0 2.3 2 0 0 2 2 2 0 Winged helix DNA-binding domain MMR_HSR1_Xtn PF16897.5 ORY13216.1 - 0.073 13.1 0.3 0.18 11.8 0.3 1.6 1 1 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Ploopntkinase3 PF18751.1 ORY13216.1 - 0.1 12.5 0.0 0.28 11.1 0.0 1.7 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 MeaB PF03308.16 ORY13216.1 - 0.12 11.4 0.6 1.3 8.0 0.0 2.7 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB KTI12 PF08433.10 ORY13216.1 - 0.12 11.8 0.1 0.35 10.3 0.0 1.8 2 0 0 2 2 2 0 Chromatin associated protein KTI12 ATP_bind_1 PF03029.17 ORY13216.1 - 0.15 11.8 0.1 16 5.2 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Oxygenase-NA PF09859.9 ORY13217.1 - 0.092 12.3 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Oxygenase, catalysing oxidative methylation of damaged DNA Pkinase PF00069.25 ORY13218.1 - 1.6e-07 31.0 0.0 1.7e-06 27.7 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY13218.1 - 0.13 11.5 0.0 0.32 10.3 0.0 1.5 1 1 0 1 1 1 0 Protein tyrosine kinase Tyrosinase PF00264.20 ORY13227.1 - 4.4e-43 148.1 0.1 5.4e-43 147.9 0.1 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase SWI-SNF_Ssr4 PF08549.10 ORY13228.1 - 4.1e-170 567.9 31.9 7.2e-169 563.8 31.9 2.5 1 1 0 1 1 1 1 Fungal domain of unknown function (DUF1750) RRM_1 PF00076.22 ORY13229.1 - 4.6e-18 64.8 0.1 9e-18 63.9 0.0 1.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Phycoerythr_ab PF02972.14 ORY13229.1 - 0.023 14.5 0.1 0.68 9.8 0.0 2.5 3 0 0 3 3 3 0 Phycoerythrin, alpha/beta chain 6PGD PF00393.19 ORY13230.1 - 1.2e-129 431.8 0.0 1.6e-129 431.5 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 ORY13230.1 - 1.1e-47 162.1 0.0 1.6e-47 161.6 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 ORY13230.1 - 0.085 13.1 0.0 0.26 11.6 0.0 1.8 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase AD PF09793.9 ORY13231.1 - 4e-25 87.8 0.3 5.4e-25 87.3 0.3 1.2 1 0 0 1 1 1 1 Anticodon-binding domain Inositol_P PF00459.25 ORY13232.1 - 2.4e-63 214.2 0.0 3e-63 213.9 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Asp PF00026.23 ORY13234.1 - 1e-24 87.5 0.0 1.2e-24 87.3 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Fungal_trans PF04082.18 ORY13235.1 - 1.1e-10 41.0 3.0 2.1e-10 40.1 3.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY13235.1 - 2.7e-06 27.4 8.9 5.6e-06 26.4 8.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro81C PF17652.1 ORY13237.1 - 3.2e-163 543.0 2.2 4.1e-163 542.6 2.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 ORY13237.1 - 9.6e-106 353.6 0.5 9.6e-106 353.6 0.5 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 81 N-terminal domain NTP_transf_2 PF01909.23 ORY13238.1 - 5.3e-06 26.6 0.0 1e-05 25.8 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Glyco_transf_20 PF00982.21 ORY13239.1 - 3.5e-148 494.2 0.0 4.8e-148 493.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 ORY13239.1 - 9.1e-84 280.2 0.0 1.5e-83 279.5 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase DUF3678 PF12435.8 ORY13241.1 - 2.3 7.7 7.0 3.5 7.1 7.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3678) GatB_N PF02934.15 ORY13242.1 - 2.6e-94 315.7 0.0 3.4e-94 315.3 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 ORY13242.1 - 3.5e-17 62.7 0.5 6.7e-17 61.8 0.0 1.7 2 0 0 2 2 2 1 GatB domain SR-25 PF10500.9 ORY13243.1 - 0.0034 17.0 19.5 0.0034 17.0 19.5 3.3 4 0 0 4 4 4 1 Nuclear RNA-splicing-associated protein FAA_hydrolase_N PF09298.11 ORY13243.1 - 0.08 13.1 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 Fumarylacetoacetase N-terminal Ribosomal_L27A PF00828.19 ORY13244.1 - 1.6e-21 77.3 0.0 2.3e-21 76.8 0.0 1.3 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Sec23_trunk PF04811.15 ORY13245.1 - 1.5e-58 198.3 0.0 2.6e-58 197.4 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 ORY13245.1 - 2.4e-25 88.3 0.0 4.6e-25 87.4 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 ORY13245.1 - 2.1e-17 63.6 0.0 3.8e-17 62.8 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 ORY13245.1 - 1.1e-15 57.3 5.2 3e-15 56.0 5.2 1.8 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 ORY13245.1 - 7.6e-07 29.0 0.0 1.5e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat Clat_adaptor_s PF01217.20 ORY13246.1 - 3.9e-56 188.9 1.2 4.6e-56 188.7 1.2 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain 3HCDH_N PF02737.18 ORY13248.1 - 7.8e-37 126.9 0.0 1.1e-36 126.4 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 ORY13248.1 - 1.1e-12 48.4 0.0 2.3e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Ldh_1_N PF00056.23 ORY13248.1 - 0.02 15.0 0.0 0.053 13.6 0.0 1.7 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 ORY13248.1 - 0.021 14.1 0.0 0.036 13.3 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_2 PF03446.15 ORY13248.1 - 0.11 12.7 0.0 0.31 11.2 0.0 1.7 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase AMP-binding PF00501.28 ORY13249.1 - 2.2e-83 280.2 0.1 2.8e-83 279.9 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORY13249.1 - 7.1e-17 62.2 0.9 1.7e-16 61.0 0.9 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Rho_RNA_bind PF07497.12 ORY13249.1 - 0.02 14.8 0.0 0.13 12.1 0.0 2.2 2 0 0 2 2 2 0 Rho termination factor, RNA-binding domain Molydop_binding PF01568.21 ORY13249.1 - 0.061 13.4 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Molydopterin dinucleotide binding domain RNA_pol_Rpb5_C PF01191.19 ORY13250.1 - 4.5e-34 116.1 0.2 7.2e-34 115.5 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 ORY13250.1 - 6.5e-24 84.3 0.0 1e-23 83.7 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain LCM PF04072.14 ORY13251.1 - 2.3e-22 79.9 0.0 5.7e-22 78.6 0.0 1.6 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase Ribonuc_L-PSP PF01042.21 ORY13253.1 - 6.8e-21 74.5 0.0 8.3e-21 74.2 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Sua5_yciO_yrdC PF01300.18 ORY13254.1 - 1e-52 178.3 0.0 1.4e-52 177.8 0.0 1.2 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.13 ORY13254.1 - 8.2e-31 107.3 0.0 1.8e-30 106.3 0.0 1.5 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding Rad21_Rec8_N PF04825.13 ORY13255.1 - 5.1e-35 120.0 0.0 1.2e-34 118.8 0.0 1.6 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 ORY13255.1 - 9.8e-10 37.6 0.0 2e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein E1-E2_ATPase PF00122.20 ORY13256.1 - 3.9e-45 153.6 1.4 5.3e-45 153.2 0.0 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 ORY13256.1 - 3.1e-44 150.9 0.5 6.3e-44 149.9 0.5 1.6 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 ORY13256.1 - 4.9e-22 79.3 1.6 3.4e-21 76.5 1.6 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 ORY13256.1 - 7.8e-19 67.1 0.0 1.7e-18 66.0 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 ORY13256.1 - 1.1e-12 47.9 0.0 2e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 ORY13256.1 - 0.00017 21.4 1.7 0.00028 20.7 0.6 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cupin_1 PF00190.22 ORY13257.1 - 2.4e-20 72.7 0.1 3.5e-20 72.2 0.1 1.1 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.11 ORY13257.1 - 3.2e-08 33.2 0.0 6.7e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.7 ORY13257.1 - 0.03 14.0 0.0 0.047 13.4 0.0 1.4 1 0 0 1 1 1 0 Cupin SHMT PF00464.19 ORY13261.1 - 6.6e-198 657.2 0.0 7.9e-198 656.9 0.0 1.1 1 0 0 1 1 1 1 Serine hydroxymethyltransferase DegT_DnrJ_EryC1 PF01041.17 ORY13261.1 - 0.12 11.7 0.0 0.42 9.9 0.0 1.8 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family MEDS PF14417.6 ORY13261.1 - 0.16 11.8 0.0 0.45 10.3 0.0 1.7 2 0 0 2 2 2 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain Adeno_PVIII PF01310.18 ORY13263.1 - 0.066 12.8 0.0 0.088 12.4 0.0 1.2 1 0 0 1 1 1 0 Adenovirus hexon associated protein, protein VIII TPR_1 PF00515.28 ORY13264.1 - 2.9e-09 36.4 2.5 0.046 13.5 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 ORY13264.1 - 6.9e-08 32.0 3.3 0.1 12.7 1.2 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY13264.1 - 5.5e-05 23.3 0.7 0.00016 21.8 0.7 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 ORY13264.1 - 8.1e-05 23.1 0.4 0.0034 17.9 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat DUF3808 PF10300.9 ORY13264.1 - 0.0003 19.7 0.4 0.00043 19.1 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_16 PF13432.6 ORY13264.1 - 0.036 14.7 1.5 0.49 11.1 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 ORY13264.1 - 0.043 14.1 1.6 0.23 11.8 0.4 2.4 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 ORY13264.1 - 0.069 14.0 1.1 27 5.9 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 ORY13264.1 - 0.31 11.1 1.5 24 5.1 0.0 3.2 2 1 1 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat Mcp5_PH PF12814.7 ORY13265.1 - 1.6e-43 147.7 0.1 3.2e-43 146.7 0.1 1.5 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology Fez1 PF06818.15 ORY13265.1 - 0.0003 21.3 13.4 0.00069 20.1 13.4 1.5 1 0 0 1 1 1 1 Fez1 Macoilin PF09726.9 ORY13265.1 - 0.022 13.3 8.8 0.054 12.1 8.8 1.7 1 0 0 1 1 1 0 Macoilin family DUF4407 PF14362.6 ORY13265.1 - 0.44 9.8 6.9 0.81 9.0 6.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2357 PF09823.9 ORY13265.1 - 0.65 9.2 5.8 1.3 8.3 5.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2357) TPR_MLP1_2 PF07926.12 ORY13265.1 - 0.73 9.9 19.6 0.49 10.5 14.5 2.4 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein APG6_N PF17675.1 ORY13265.1 - 1.1 9.8 13.1 3.4 8.2 13.1 1.9 1 0 0 1 1 1 0 Apg6 coiled-coil region FapA PF03961.13 ORY13265.1 - 7.1 5.1 5.7 11 4.6 5.7 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A RRM_1 PF00076.22 ORY13266.1 - 2.1e-18 65.9 1.4 5.3e-18 64.6 0.4 1.9 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 ORY13266.1 - 1.8e-05 24.4 0.1 2e-05 24.2 0.1 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 ORY13266.1 - 0.0096 15.8 0.0 0.014 15.3 0.0 1.2 1 0 0 1 1 1 1 Occluded RNA-recognition motif DPCD PF14913.6 ORY13266.1 - 0.05 13.0 0.1 0.074 12.4 0.1 1.2 1 0 0 1 1 1 0 DPCD protein family JmjC PF02373.22 ORY13267.1 - 3.5e-09 37.1 0.1 4e-08 33.7 0.1 2.3 1 1 0 1 1 1 1 JmjC domain, hydroxylase PHD PF00628.29 ORY13267.1 - 3.9e-08 33.1 4.9 3.9e-08 33.1 4.9 2.4 2 0 0 2 2 2 1 PHD-finger JHD PF17811.1 ORY13267.1 - 7.3e-07 29.7 0.6 1.8e-06 28.5 0.6 1.6 1 0 0 1 1 1 1 Jumonji helical domain Cupin_8 PF13621.6 ORY13267.1 - 2.2e-06 27.6 0.1 8.1e-06 25.7 0.1 1.8 1 1 0 1 1 1 1 Cupin-like domain PHD_2 PF13831.6 ORY13267.1 - 0.025 14.1 5.2 0.023 14.3 2.7 2.3 2 0 0 2 2 2 0 PHD-finger Dickkopf_N PF04706.12 ORY13267.1 - 0.63 10.6 8.9 4.3 7.9 1.4 2.7 2 0 0 2 2 2 0 Dickkopf N-terminal cysteine-rich region Zn_clus PF00172.18 ORY13267.1 - 1.3 9.3 23.4 1.3 9.2 7.0 3.2 3 0 0 3 3 3 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_Tnp_IS91 PF14319.6 ORY13267.1 - 2.1 8.4 4.2 0.92 9.6 0.2 2.4 2 0 0 2 2 2 0 Transposase zinc-binding domain RasGEF PF00617.19 ORY13269.1 - 7.6e-47 159.8 0.3 1.2e-46 159.2 0.3 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 ORY13269.1 - 9.4e-13 48.3 0.6 2.2e-12 47.1 0.6 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif Glyco_transf_22 PF03901.17 ORY13271.1 - 4.2e-84 283.2 14.2 5.1e-84 282.9 14.2 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family DUF3445 PF11927.8 ORY13271.1 - 2.2e-78 263.0 0.0 3e-78 262.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) DUF4059 PF13268.6 ORY13271.1 - 0.096 13.1 0.1 1.5 9.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4059) Gar1 PF04410.14 ORY13272.1 - 6.1e-23 81.3 0.2 7.4e-23 81.0 0.2 1.1 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region PP2C PF00481.21 ORY13274.1 - 7.1e-52 176.6 0.0 1.1e-51 175.9 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_8 PF13855.6 ORY13274.1 - 2.6e-40 136.0 47.6 1.1e-09 37.9 6.9 10.4 5 2 6 12 12 12 12 Leucine rich repeat LRR_4 PF12799.7 ORY13274.1 - 7e-36 121.7 49.7 0.00015 22.1 2.6 12.3 8 2 5 15 15 15 11 Leucine Rich repeats (2 copies) Guanylate_cyc PF00211.20 ORY13274.1 - 3e-30 105.2 0.0 2e-29 102.5 0.0 2.0 1 1 1 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain LRR_1 PF00560.33 ORY13274.1 - 1.4e-09 37.1 44.9 7.8 7.5 0.1 16.0 16 4 0 16 16 16 3 Leucine Rich Repeat LRR_9 PF14580.6 ORY13274.1 - 5e-08 32.6 13.5 0.051 13.1 0.3 4.9 2 1 3 5 5 5 4 Leucine-rich repeat Ad_cyc_g-alpha PF08509.11 ORY13274.1 - 4.1e-07 29.6 0.6 1.2e-06 28.1 0.6 1.8 1 0 0 1 1 1 1 Adenylate cyclase G-alpha binding domain LRR_5 PF13306.6 ORY13274.1 - 8.4e-05 22.5 0.3 0.28 11.1 0.1 3.6 3 0 0 3 3 3 1 BspA type Leucine rich repeat region (6 copies) RA PF00788.23 ORY13274.1 - 0.00015 22.4 0.0 0.00045 20.8 0.0 1.8 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain DNA_ligase_ZBD PF03119.16 ORY13275.1 - 0.011 15.8 0.4 0.022 14.8 0.4 1.4 1 0 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain zf-NADH-PPase PF09297.11 ORY13275.1 - 0.075 12.7 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain DUF16 PF01519.16 ORY13275.1 - 0.079 13.4 0.7 0.29 11.6 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function DUF16 DUF3176 PF11374.8 ORY13276.1 - 1.3e-15 57.5 0.2 1.5e-15 57.3 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) BRCT_2 PF16589.5 ORY13281.1 - 9.5e-13 48.4 0.0 1.6e-12 47.6 0.0 1.4 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 ORY13281.1 - 6.7e-05 22.8 0.3 0.00022 21.1 0.0 1.9 2 0 0 2 2 2 1 twin BRCT domain BRCT PF00533.26 ORY13281.1 - 0.00037 20.8 0.0 0.00066 20.0 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 ORY13281.1 - 0.0026 18.0 0.0 0.005 17.1 0.0 1.4 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain XPG_I PF00867.18 ORY13282.1 - 1e-32 112.3 0.8 4.5e-32 110.2 0.0 2.3 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.17 ORY13282.1 - 1.8e-30 105.4 0.0 1.8e-30 105.4 0.0 1.8 2 0 0 2 2 2 1 XPG N-terminal domain 5_3_exonuc PF01367.20 ORY13282.1 - 1.6e-06 28.6 1.3 8.1e-06 26.4 0.0 2.6 2 1 1 3 3 3 1 5'-3' exonuclease, C-terminal SAM fold Acyl-CoA_dh_N PF02771.16 ORY13283.1 - 4.3e-24 85.3 0.2 8.2e-24 84.5 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 ORY13283.1 - 9.3e-23 81.1 0.1 1.5e-22 80.4 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 ORY13283.1 - 1.8e-16 60.1 0.0 3.4e-16 59.2 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 ORY13283.1 - 1.2e-05 25.6 0.1 2.2e-05 24.7 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain UQ_con PF00179.26 ORY13284.1 - 1.2e-47 161.0 0.0 1.4e-47 160.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 ORY13284.1 - 0.073 13.4 0.0 0.087 13.1 0.0 1.3 1 0 0 1 1 1 0 RWD domain Prok-E2_B PF14461.6 ORY13284.1 - 0.12 12.1 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B Glyco_hydro_15 PF00723.21 ORY13285.1 - 4.5e-12 45.5 0.0 5.2e-12 45.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 MPDZ_u10 PF16667.5 ORY13288.1 - 0.0059 17.5 1.3 0.0059 17.5 1.3 2.8 2 0 0 2 2 2 1 Unstructured region 10 on multiple PDZ protein SURF6 PF04935.12 ORY13289.1 - 1.1e-46 159.1 33.5 1.1e-46 159.1 33.5 3.5 2 1 1 3 3 3 1 Surfeit locus protein 6 RRP14 PF15459.6 ORY13289.1 - 1.2e-16 61.0 0.4 1.2e-16 61.0 0.4 8.7 5 2 2 7 7 7 1 60S ribosome biogenesis protein Rrp14 Fer4 PF00037.27 ORY13290.1 - 2.3e-14 52.5 15.3 2e-08 33.7 3.5 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 ORY13290.1 - 5.5e-13 49.3 9.8 8.3e-13 48.7 9.8 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 ORY13290.1 - 7.3e-11 42.8 7.6 2.9e-05 24.9 0.5 2.2 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 ORY13290.1 - 1.5e-10 41.1 31.8 6.7e-07 29.3 11.8 2.1 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_10 PF13237.6 ORY13290.1 - 4.5e-09 36.3 21.4 2.6e-06 27.4 12.5 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 ORY13290.1 - 1.7e-08 34.5 10.2 2.9e-08 33.7 10.2 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 ORY13290.1 - 2.8e-07 30.9 19.1 0.00012 22.5 11.2 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 ORY13290.1 - 9.8e-07 28.6 16.9 0.0004 20.3 5.4 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 ORY13290.1 - 3.8e-06 26.7 12.1 0.0081 16.2 1.7 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 ORY13290.1 - 6.7e-06 26.2 10.8 0.0003 21.1 1.8 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 ORY13290.1 - 0.00022 21.7 12.2 0.0057 17.2 12.9 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_3 PF12798.7 ORY13290.1 - 0.011 16.7 15.7 0.018 15.9 3.5 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_13 PF13370.6 ORY13290.1 - 0.028 15.0 15.2 0.75 10.4 4.3 2.6 2 1 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I c-SKI_SMAD_bind PF08782.10 ORY13290.1 - 0.028 14.6 5.1 1 9.6 0.3 2.2 1 1 1 2 2 2 0 c-SKI Smad4 binding domain Fer4_18 PF13746.6 ORY13290.1 - 0.074 13.3 8.9 2.8 8.2 1.2 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain ETF_QO PF05187.13 ORY13290.1 - 0.077 13.1 5.2 0.42 10.8 0.4 2.2 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_22 PF17179.4 ORY13290.1 - 0.65 10.9 11.6 1.6 9.6 1.4 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain PP-binding PF00550.25 ORY13291.1 - 1.2e-10 41.6 0.1 1.6e-10 41.2 0.1 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 ORY13291.1 - 8.2e-09 35.6 0.1 1e-08 35.3 0.1 1.1 1 0 0 1 1 1 1 Acyl-carrier GPP34 PF05719.11 ORY13292.1 - 3.3e-68 229.8 0.1 4.2e-68 229.4 0.1 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) SNF5 PF04855.12 ORY13293.1 - 6.2e-66 222.6 0.3 1.7e-64 217.9 0.3 2.4 1 1 0 1 1 1 1 SNF5 / SMARCB1 / INI1 PHD PF00628.29 ORY13294.1 - 1.2e-11 44.3 23.5 6.9e-08 32.3 10.9 2.9 2 1 1 3 3 3 2 PHD-finger Peptidase_M24 PF00557.24 ORY13294.1 - 9.7e-05 22.2 0.0 0.00018 21.3 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 DUF963 PF06131.11 ORY13294.1 - 0.031 13.7 4.3 0.032 13.7 0.7 2.6 2 0 0 2 2 2 0 Schizosaccharomyces pombe repeat of unknown function (DUF963) dsRBD2 PF17842.1 ORY13294.1 - 0.83 9.8 3.5 3.1 8.0 3.5 2.0 1 0 0 1 1 1 0 Double-stranded RNA binding domain 2 tRNA-synt_2 PF00152.20 ORY13295.1 - 2.3e-89 299.6 0.4 3.5e-89 299.0 0.0 1.3 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 ORY13295.1 - 3.1e-09 36.7 0.0 6e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Ins134_P3_kin PF05770.11 ORY13295.1 - 0.057 12.9 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain DOPA_dioxygen PF08883.11 ORY13296.1 - 8.9e-40 135.2 0.0 7.5e-38 129.0 0.0 2.1 1 1 0 1 1 1 1 Dopa 4,5-dioxygenase family SRP14 PF02290.15 ORY13297.1 - 1.9e-30 105.0 0.0 1.9e-30 105.0 0.0 1.7 2 0 0 2 2 2 1 Signal recognition particle 14kD protein AP3D1 PF06375.11 ORY13297.1 - 5.3 7.2 11.3 6.9 6.9 10.9 1.4 1 1 0 1 1 1 0 AP-3 complex subunit delta-1 Pyr_redox_2 PF07992.14 ORY13298.1 - 2.6e-66 223.9 7.0 4.6e-66 223.0 7.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 ORY13298.1 - 1.7e-39 134.5 0.1 4.9e-39 133.0 0.1 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain MA3 PF02847.17 ORY13298.1 - 3.7e-24 84.9 0.0 6.9e-24 84.0 0.0 1.5 1 0 0 1 1 1 1 MA3 domain Pyr_redox PF00070.27 ORY13298.1 - 1.6e-21 76.7 9.1 1.2e-19 70.7 1.5 3.0 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase MIF4G PF02854.19 ORY13298.1 - 1.5e-20 73.8 2.1 1.7e-20 73.6 1.0 1.7 2 0 0 2 2 2 1 MIF4G domain NAD_binding_8 PF13450.6 ORY13298.1 - 4.9e-09 36.3 3.8 1.7e-05 24.9 1.2 2.7 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 ORY13298.1 - 1.5e-08 34.5 0.2 1.5e-08 34.5 0.2 2.7 2 1 1 3 3 3 1 FAD dependent oxidoreductase GIDA PF01134.22 ORY13298.1 - 3.3e-08 33.0 5.6 1.3e-07 31.1 0.7 2.4 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 ORY13298.1 - 6.4e-07 28.9 8.0 2.7e-05 23.6 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ORY13298.1 - 1.4e-06 27.7 4.4 1.4e-06 27.7 4.4 2.2 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.21 ORY13298.1 - 2.8e-05 23.5 9.6 0.029 13.7 1.0 3.3 4 0 0 4 4 4 2 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 ORY13298.1 - 8.1e-05 22.0 3.6 8.5e-05 21.9 0.2 2.3 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 ORY13298.1 - 0.00055 18.8 2.9 0.00055 18.8 2.9 3.7 4 0 0 4 4 4 1 HI0933-like protein DAO PF01266.24 ORY13298.1 - 0.0027 17.3 13.1 0.015 14.9 0.9 3.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 ORY13298.1 - 0.0043 16.2 0.4 2.5 7.2 0.0 2.8 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 ORY13298.1 - 0.0068 15.7 10.8 0.17 11.1 1.9 2.9 2 1 0 2 2 2 2 FAD binding domain NAD_binding_7 PF13241.6 ORY13298.1 - 0.049 14.1 0.9 3.6 8.1 0.1 3.0 2 0 0 2 2 2 0 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.19 ORY13298.1 - 0.25 10.7 0.9 8.5 5.7 0.0 2.5 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Amino_oxidase PF01593.24 ORY13298.1 - 0.25 10.6 1.1 0.33 10.2 0.0 1.7 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase VATC PF18716.1 ORY13298.1 - 0.65 9.9 2.3 1.2 9.0 2.3 1.3 1 0 0 1 1 1 0 Vms1-associating treble clef domain Lycopene_cycl PF05834.12 ORY13298.1 - 2.7 6.9 8.0 0.48 9.4 2.1 2.4 2 0 0 2 2 2 0 Lycopene cyclase protein 3HCDH_N PF02737.18 ORY13298.1 - 7.3 6.4 9.6 0.53 10.1 1.4 2.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Drc1-Sld2 PF11719.8 ORY13299.1 - 2.5e-84 284.4 19.9 3.4e-84 284.0 19.9 1.2 1 0 0 1 1 1 1 DNA replication and checkpoint protein CSN8_PSD8_EIF3K PF10075.9 ORY13299.1 - 2.8e-19 69.5 0.0 8.5e-19 68.0 0.0 1.7 2 0 0 2 2 2 1 CSN8/PSMD8/EIF3K family SAC3_GANP PF03399.16 ORY13299.1 - 0.035 13.5 0.0 0.084 12.3 0.0 1.6 1 0 0 1 1 1 0 SAC3/GANP family Ribosomal_L11_N PF03946.14 ORY13300.1 - 5.3e-27 93.4 0.1 1e-26 92.5 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 ORY13300.1 - 7.9e-21 74.3 5.9 8.3e-21 74.3 3.7 2.1 2 1 0 2 2 2 1 Ribosomal protein L11, RNA binding domain Zn_clus PF00172.18 ORY13301.1 - 5.9e-08 32.7 9.5 1.7e-07 31.2 9.5 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ORY13301.1 - 0.00014 21.0 0.0 0.00072 18.7 0.0 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain NIF PF03031.18 ORY13302.1 - 1.7e-24 86.4 0.1 3.1e-24 85.5 0.1 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase BRCT PF00533.26 ORY13302.1 - 3.8e-08 33.6 0.0 1e-07 32.2 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 ORY13302.1 - 5.1e-06 26.4 0.1 1.1e-05 25.3 0.1 1.5 1 0 0 1 1 1 1 twin BRCT domain BRCT_2 PF16589.5 ORY13302.1 - 9.1e-06 26.0 0.2 3.8e-05 24.0 0.0 2.2 2 1 1 3 3 3 1 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 ORY13302.1 - 0.055 13.8 0.4 0.14 12.5 0.0 1.9 2 0 0 2 2 2 0 DNA ligase 3 BRCT domain U79_P34 PF03064.16 ORY13302.1 - 2.4 7.5 10.5 0.83 9.0 2.4 2.3 2 0 0 2 2 2 0 HSV U79 / HCMV P34 Glyco_transf_28 PF03033.20 ORY13303.1 - 4.9e-29 101.1 0.0 9.9e-29 100.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain GRAM PF02893.20 ORY13303.1 - 2.6e-28 98.2 7.1 3.7e-18 65.4 0.4 3.4 3 0 0 3 3 3 3 GRAM domain PH PF00169.29 ORY13303.1 - 1.2e-12 48.3 0.1 3.1e-12 46.9 0.1 1.8 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 ORY13303.1 - 1.8e-06 28.3 0.4 6.4e-06 26.5 0.4 2.0 1 1 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.6 ORY13303.1 - 2.7e-05 24.2 0.1 6.4e-05 23.0 0.1 1.6 1 0 0 1 1 1 1 PH domain UDPGT PF00201.18 ORY13303.1 - 8.6e-05 21.5 0.0 0.00016 20.6 0.0 1.4 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH_8 PF15409.6 ORY13303.1 - 0.00097 19.4 0.2 0.0033 17.7 0.2 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain PH_2 PF08458.10 ORY13303.1 - 0.0016 18.8 0.0 0.0045 17.3 0.0 1.7 1 0 0 1 1 1 1 Plant pleckstrin homology-like region PH_13 PF16652.5 ORY13303.1 - 0.01 15.7 0.1 0.021 14.7 0.1 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain Asp PF00026.23 ORY13304.1 - 1.4e-106 356.5 0.1 1.6e-106 356.3 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 ORY13304.1 - 5.6e-15 56.0 1.8 1.1e-12 48.6 1.5 2.6 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 ORY13304.1 - 0.00035 21.1 0.0 0.54 10.9 0.0 3.3 3 2 0 3 3 3 2 Aspartyl protease gag-asp_proteas PF13975.6 ORY13304.1 - 0.00043 20.8 0.0 0.41 11.2 0.0 3.0 3 0 0 3 3 3 2 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 ORY13304.1 - 0.0046 16.7 0.0 0.1 12.4 0.0 2.4 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal EI24 PF07264.11 ORY13305.1 - 8.3e-11 42.5 12.7 1.4e-10 41.7 12.7 1.4 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) PrgI PF12666.7 ORY13305.1 - 1.6 9.5 0.0 1.6 9.5 0.0 3.2 3 1 0 3 3 3 0 PrgI family protein PALP PF00291.25 ORY13306.1 - 3.5e-56 190.8 0.1 4.2e-56 190.5 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Mad3_BUB1_I PF08311.12 ORY13307.1 - 1.6e-45 154.1 1.4 3.7e-45 152.9 1.4 1.7 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Pkinase PF00069.25 ORY13307.1 - 4.3e-13 49.2 0.1 4.2e-12 46.0 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY13307.1 - 7.9e-06 25.3 0.1 0.00013 21.3 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 ORY13307.1 - 0.016 14.6 0.1 0.029 13.7 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Mad3_BUB1_II PF08171.11 ORY13307.1 - 0.017 15.2 0.0 0.08 13.1 0.0 2.2 2 0 0 2 2 2 0 Mad3/BUB1 homology region 2 APH PF01636.23 ORY13307.1 - 0.083 12.8 0.6 0.36 10.7 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family Mad3_BUB1_I_2 PF17014.5 ORY13307.1 - 0.14 12.3 0.0 0.49 10.5 0.0 1.8 2 0 0 2 2 2 0 Putative Mad3/BUB1 like region 1 protein Ribosomal_60s PF00428.19 ORY13307.1 - 2.9 8.5 14.4 0.79 10.4 7.3 3.4 3 0 0 3 3 3 0 60s Acidic ribosomal protein PCI PF01399.27 ORY13308.1 - 1.1e-07 32.3 0.0 2.4e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 PCI domain TPR_8 PF13181.6 ORY13308.1 - 0.11 12.7 0.3 0.45 10.9 0.3 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat MIT PF04212.18 ORY13309.1 - 7.3e-15 54.8 0.7 2e-14 53.4 0.7 1.8 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain DUF2564 PF10819.8 ORY13310.1 - 0.047 14.1 0.1 2.9 8.3 0.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2564) FAD_binding_4 PF01565.23 ORY13311.1 - 0.00023 20.9 0.0 0.00046 19.9 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain FAD_binding_4 PF01565.23 ORY13312.1 - 1.3e-13 50.9 0.8 2.8e-13 49.8 0.2 1.9 2 0 0 2 2 2 1 FAD binding domain CoA_trans PF01144.23 ORY13313.1 - 1.3e-102 341.8 0.6 5.2e-63 212.3 0.2 2.0 2 0 0 2 2 2 2 Coenzyme A transferase Mal_decarbox_Al PF16957.5 ORY13313.1 - 0.0027 16.1 0.2 0.045 12.1 0.1 2.0 2 0 0 2 2 2 2 Malonate decarboxylase, alpha subunit, transporter AAA PF00004.29 ORY13314.1 - 5.6e-05 23.6 0.4 0.027 14.9 0.1 2.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 ORY13314.1 - 0.0071 16.7 0.0 0.014 15.8 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 ORY13314.1 - 0.06 13.6 0.1 0.26 11.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain Acyl-CoA_dh_1 PF00441.24 ORY13316.1 - 2.5e-25 89.4 0.0 4.6e-25 88.6 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DASH_Spc34 PF08657.10 ORY13316.1 - 2e-23 83.5 0.0 1.4e-21 77.4 0.0 2.1 1 1 1 2 2 2 1 DASH complex subunit Spc34 Acyl-CoA_dh_N PF02771.16 ORY13316.1 - 1.8e-16 60.8 0.0 5.3e-16 59.3 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 ORY13316.1 - 6.6e-08 32.9 1.1 1.7e-07 31.6 0.0 2.2 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 ORY13316.1 - 8.1e-06 25.9 0.0 2e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Lebercilin PF15619.6 ORY13316.1 - 0.065 12.9 2.0 0.11 12.2 2.0 1.3 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Tropomyosin_1 PF12718.7 ORY13316.1 - 0.18 11.9 4.2 0.46 10.6 4.2 1.6 1 0 0 1 1 1 0 Tropomyosin like Rpn3_C PF08375.11 ORY13317.1 - 1.2e-26 92.9 2.3 3.2e-26 91.5 2.3 1.8 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI PF01399.27 ORY13317.1 - 3.3e-23 82.2 0.1 2.2e-22 79.5 0.1 2.3 2 0 0 2 2 2 1 PCI domain TPR_2 PF07719.17 ORY13317.1 - 0.055 13.6 0.0 0.24 11.6 0.0 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat Sigma70_r1_2 PF00140.20 ORY13317.1 - 0.95 9.5 5.2 0.77 9.8 2.4 2.2 2 0 0 2 2 2 0 Sigma-70 factor, region 1.2 Ank_2 PF12796.7 ORY13318.1 - 1.2e-22 80.3 11.8 9.9e-09 35.7 0.0 2.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY13318.1 - 5.6e-20 71.4 1.5 2e-08 34.6 0.1 3.4 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 ORY13318.1 - 1.2e-15 57.3 4.7 1e-05 25.7 0.8 4.6 2 1 3 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY13318.1 - 1.1e-11 43.9 6.0 0.02 15.4 0.0 5.6 6 0 0 6 6 6 3 Ankyrin repeat Ank PF00023.30 ORY13318.1 - 4.9e-11 42.6 10.2 0.0017 18.7 1.0 5.4 5 0 0 5 5 5 3 Ankyrin repeat SieB PF14163.6 ORY13319.1 - 0.0086 15.6 1.5 0.022 14.3 1.5 1.7 1 0 0 1 1 1 1 Super-infection exclusion protein B COX14 PF14880.6 ORY13319.1 - 6.9 6.6 6.9 4 7.3 0.2 2.7 3 0 0 3 3 3 0 Cytochrome oxidase c assembly Band_7 PF01145.25 ORY13320.1 - 3.4e-15 56.5 0.1 3.4e-15 56.5 0.1 2.5 2 1 0 2 2 2 1 SPFH domain / Band 7 family Mago-bind PF09282.10 ORY13322.1 - 4.2e-15 55.3 5.2 7.8e-15 54.4 5.2 1.5 1 0 0 1 1 1 1 Mago binding DUF4407 PF14362.6 ORY13322.1 - 0.48 9.7 3.4 0.56 9.5 3.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4551 PF15087.6 ORY13322.1 - 2.7 6.7 4.1 2.9 6.6 4.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) HET PF06985.11 ORY13348.1 - 1.9e-22 80.2 0.0 2.1e-22 80.0 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Flavin_Reduct PF01613.18 ORY13350.1 - 1.4e-20 73.9 0.0 2.1e-20 73.4 0.0 1.2 1 0 0 1 1 1 1 Flavin reductase like domain Abhydrolase_1 PF00561.20 ORY13351.1 - 4.8e-09 36.2 0.0 1.7e-07 31.1 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ORY13351.1 - 0.0049 16.2 0.0 0.094 12.0 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ORY13351.1 - 0.023 15.3 0.0 0.03 14.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 ORY13351.1 - 0.056 12.9 0.0 2.4 7.6 0.0 2.3 2 1 0 2 2 2 0 Prolyl oligopeptidase family PAP_central PF04928.17 ORY13352.1 - 4.6e-99 330.4 0.0 6.1e-99 330.0 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 ORY13352.1 - 2.4e-53 180.3 0.0 4.4e-53 179.4 0.0 1.5 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 ORY13352.1 - 9.2e-12 45.1 0.0 2.6e-11 43.7 0.0 1.7 2 0 0 2 2 2 1 Nucleotidyltransferase domain Polbeta PF18765.1 ORY13352.1 - 0.0037 17.3 0.0 0.0096 16.0 0.0 1.6 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase YlbD_coat PF14071.6 ORY13352.1 - 0.14 12.4 1.1 1.1 9.5 0.0 2.6 3 0 0 3 3 3 0 Putative coat protein IBR PF01485.21 ORY13353.1 - 2.3e-09 37.3 19.6 3.4e-06 27.2 2.9 3.5 4 1 0 4 4 4 2 IBR domain, a half RING-finger domain DEAD PF00270.29 ORY13354.1 - 4.2e-49 166.7 0.1 7e-49 166.0 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY13354.1 - 6.9e-29 100.4 0.1 1.6e-27 96.0 0.1 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain UTP25 PF06862.12 ORY13354.1 - 0.0029 16.4 1.6 0.017 14.0 0.1 2.5 2 1 1 3 3 3 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 CDP-OH_P_transf PF01066.21 ORY13355.1 - 1.2e-11 45.2 0.2 1.2e-11 45.2 0.2 2.0 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase DUF1772 PF08592.11 ORY13356.1 - 2.3e-22 79.8 2.5 3.6e-22 79.2 2.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) PAP2 PF01569.21 ORY13357.1 - 8.9e-29 100.0 6.0 8.9e-29 100.0 6.0 1.9 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 ORY13357.1 - 0.00033 20.4 12.5 0.0059 16.3 7.0 3.1 2 1 0 2 2 2 2 PAP2 superfamily DUF983 PF06170.12 ORY13357.1 - 0.04 14.3 6.2 0.9 10.0 0.3 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF983) TPPK_C PF12555.8 ORY13357.1 - 0.38 10.8 5.6 49 4.1 0.2 3.8 3 2 0 3 3 3 0 Thiamine pyrophosphokinase C terminal PAP2_C PF14360.6 ORY13357.1 - 2.2 8.9 7.2 0.29 11.7 2.0 2.1 2 0 0 2 2 2 0 PAP2 superfamily C-terminal ALO PF04030.14 ORY13358.1 - 3.7e-85 285.9 1.3 5.7e-85 285.3 1.3 1.3 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 ORY13358.1 - 7.4e-32 110.0 0.0 1.1e-31 109.5 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain HET PF06985.11 ORY13359.1 - 4.8e-09 36.7 1.3 5.8e-09 36.5 1.3 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) adh_short PF00106.25 ORY13360.1 - 8.4e-27 93.9 0.3 1.2e-26 93.4 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY13360.1 - 2.4e-18 66.6 0.0 3.2e-18 66.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY13360.1 - 1.9e-09 37.7 0.3 3.1e-09 37.0 0.3 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 ORY13360.1 - 6.1e-06 25.6 0.0 6.6e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.20 ORY13360.1 - 0.03 14.4 0.0 0.064 13.3 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.21 ORY13360.1 - 0.033 13.6 0.2 0.41 10.1 0.2 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family MFS_1 PF07690.16 ORY13362.1 - 6.8e-31 107.5 34.8 6.8e-31 107.5 34.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Ldh_2 PF02615.14 ORY13365.1 - 9.3e-122 406.3 0.6 1.1e-121 406.1 0.6 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase Sugar_tr PF00083.24 ORY13366.1 - 5.2e-83 279.4 23.7 5.9e-83 279.2 23.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY13366.1 - 5.9e-17 61.6 23.9 5.9e-17 61.6 23.9 2.1 1 1 0 2 2 2 1 Major Facilitator Superfamily Glyco_hydro_62 PF03664.13 ORY13367.1 - 3.4e-59 200.4 10.8 4e-59 200.2 10.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 KAR9 PF08580.10 ORY13368.1 - 4.7 5.6 4.8 5.2 5.5 4.8 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 DUF5408 PF17402.2 ORY13369.1 - 0.82 9.6 3.1 29 4.6 0.1 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF5408) Ycf70 PF17382.2 ORY13369.1 - 4 7.9 5.0 13 6.3 0.1 2.7 3 0 0 3 3 3 0 Uncharacterized Ycf70-like Cas1_AcylT PF07779.12 ORY13371.1 - 8.7e-116 387.6 14.9 1.3e-115 387.1 14.9 1.1 1 0 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p DUF805 PF05656.14 ORY13371.1 - 2.8 8.4 13.9 0.036 14.5 1.7 3.5 2 1 0 2 2 2 0 Protein of unknown function (DUF805) RHH_6 PF16762.5 ORY13374.1 - 7.9 7.2 13.4 15 6.3 4.7 3.0 2 1 0 2 2 2 0 Ribbon-helix-helix domain Zn_clus PF00172.18 ORY13375.1 - 0.057 13.6 5.7 0.13 12.4 5.7 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Carla_C4 PF01623.17 ORY13375.1 - 0.22 11.5 2.2 0.61 10.1 2.2 1.7 1 0 0 1 1 1 0 Carlavirus putative nucleic acid binding protein DUF4861 PF16153.5 ORY13376.1 - 0.026 13.5 0.7 0.035 13.1 0.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4861) ADH_N PF08240.12 ORY13377.1 - 8.7e-26 89.9 0.3 1.4e-25 89.3 0.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORY13377.1 - 1.1e-15 57.7 0.0 1.7e-15 57.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 ORY13377.1 - 0.0011 18.4 0.1 0.0037 16.6 0.1 1.7 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 ORY13377.1 - 0.0063 15.8 0.3 0.0097 15.2 0.3 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Churchill PF06573.11 ORY13377.1 - 0.076 13.3 0.0 0.13 12.6 0.0 1.3 1 0 0 1 1 1 0 Churchill protein ATPase_gene1 PF09527.10 ORY13380.1 - 0.014 15.6 0.4 0.026 14.7 0.4 1.4 1 0 0 1 1 1 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter Cytochrom_B561 PF03188.16 ORY13387.1 - 0.0021 18.2 12.6 0.0038 17.4 12.6 1.3 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF4834 PF16118.5 ORY13387.1 - 1.3 10.0 0.0 1.3 10.0 0.0 2.3 3 1 0 3 3 3 0 Domain of unknown function (DUF4834) DUF2427 PF10348.9 ORY13387.1 - 1.9 8.3 9.1 4.5 7.1 8.3 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF2427) Cation_ATPase_C PF00689.21 ORY13388.1 - 0.076 12.7 7.0 0.44 10.2 6.9 2.2 1 1 0 1 1 1 0 Cation transporting ATPase, C-terminus ANAPC4_WD40 PF12894.7 ORY13390.1 - 0.0054 17.0 0.0 6.5 7.1 0.0 3.7 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 ORY13390.1 - 0.0061 17.4 4.5 5.3 8.1 0.0 5.2 4 1 0 4 4 4 1 WD domain, G-beta repeat DUF1989 PF09347.10 ORY13391.1 - 3.5e-66 222.0 0.0 4.2e-66 221.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) A_deaminase PF00962.22 ORY13392.1 - 2.4e-78 263.8 0.0 2.8e-78 263.6 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase Amidohydro_1 PF01979.20 ORY13392.1 - 0.047 13.0 0.0 0.93 8.7 0.0 2.1 1 1 1 2 2 2 0 Amidohydrolase family Fungal_trans PF04082.18 ORY13395.1 - 1.7e-17 63.3 0.0 3.4e-17 62.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY13395.1 - 1.3e-07 31.6 14.2 2.7e-07 30.6 14.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HAP1_N PF04849.13 ORY13395.1 - 0.022 14.0 1.3 0.036 13.3 1.3 1.2 1 0 0 1 1 1 0 HAP1 N-terminal conserved region Herpes_BLRF2 PF05812.12 ORY13395.1 - 0.041 14.0 0.4 0.082 13.0 0.4 1.4 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein DUF5094 PF17015.5 ORY13395.1 - 0.11 12.6 1.6 0.18 11.9 1.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5094) Tmemb_cc2 PF10267.9 ORY13395.1 - 0.12 11.4 2.4 0.18 10.9 2.4 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein TSC22 PF01166.18 ORY13395.1 - 0.15 12.4 0.1 0.32 11.3 0.1 1.5 1 0 0 1 1 1 0 TSC-22/dip/bun family Pyridoxal_deC PF00282.19 ORY13396.1 - 1e-75 254.8 0.0 1.5e-75 254.3 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 ORY13396.1 - 0.0012 17.8 0.0 0.002 17.2 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V HMGL-like PF00682.19 ORY13397.1 - 1.3e-80 270.8 0.0 2.2e-80 270.0 0.0 1.4 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 ORY13397.1 - 7.5e-25 87.4 0.0 1.8e-24 86.2 0.0 1.6 1 1 0 1 1 1 1 LeuA allosteric (dimerisation) domain Sigma_reg_N PF13800.6 ORY13397.1 - 0.099 12.9 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Sigma factor regulator N-terminal DUF2347 PF09804.9 ORY13398.1 - 7.2e-89 298.1 0.0 1.1e-88 297.5 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) DUF4484 PF14831.6 ORY13398.1 - 2.5e-35 122.4 13.4 9.1e-15 55.3 0.2 4.2 2 1 2 4 4 4 3 Domain of unknown function (DUF4484) SPA PF08616.10 ORY13398.1 - 0.0032 17.4 0.0 0.011 15.6 0.0 1.8 1 1 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.9 ORY13398.1 - 0.026 13.2 0.0 9.3 4.8 0.0 2.9 2 1 0 3 3 3 0 Transport protein Avl9 BP28CT PF08146.12 ORY13399.1 - 1.1e-36 126.1 1.0 1.1e-36 126.1 1.0 3.1 3 0 0 3 3 3 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.8 ORY13399.1 - 3.6e-23 82.1 0.5 3.6e-23 82.1 0.5 6.5 11 0 0 11 11 11 1 U3 small nucleolar RNA-associated protein 10 HEAT PF02985.22 ORY13399.1 - 0.024 14.9 17.3 0.18 12.2 0.3 7.8 9 0 0 9 9 9 0 HEAT repeat HEAT_EZ PF13513.6 ORY13399.1 - 0.047 14.2 12.3 0.25 11.9 0.3 6.2 5 1 0 5 5 5 0 HEAT-like repeat NRDE-2 PF08424.10 ORY13400.1 - 1.3e-86 290.7 0.8 1.3e-85 287.4 0.6 2.2 2 0 0 2 2 2 1 NRDE-2, necessary for RNA interference TPR_17 PF13431.6 ORY13400.1 - 0.012 15.9 0.0 0.53 10.8 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 ORY13400.1 - 0.16 12.3 1.2 1.3 9.4 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Syja_N PF02383.18 ORY13401.1 - 7e-93 311.4 0.0 1.1e-92 310.8 0.0 1.3 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.8 ORY13401.1 - 8.3e-33 112.5 0.0 1.5e-32 111.7 0.0 1.4 1 0 0 1 1 1 1 Inositol phosphatase HET PF06985.11 ORY13402.1 - 2.8e-33 115.3 0.0 5.6e-33 114.4 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Orthopox_C10L PF07020.11 ORY13402.1 - 0.15 12.8 0.0 0.36 11.6 0.0 1.6 1 0 0 1 1 1 0 Orthopoxvirus C10L protein Sugar_tr PF00083.24 ORY13403.1 - 1.1e-107 360.8 20.3 1.3e-107 360.5 20.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY13403.1 - 1.7e-26 93.0 33.6 1.3e-25 90.1 25.8 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily PI-PLC-C1 PF16670.5 ORY13404.1 - 6.7e-129 429.7 0.0 7.6e-129 429.5 0.0 1.0 1 0 0 1 1 1 1 Phosphoinositide phospholipase C, Ca2+-dependent adh_short PF00106.25 ORY13405.1 - 9.9e-34 116.5 0.0 2.2e-33 115.4 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY13405.1 - 5.6e-23 81.7 0.0 9.3e-23 81.0 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY13405.1 - 1.1e-08 35.2 0.0 1.5e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 ORY13405.1 - 0.00011 22.2 0.0 0.00014 21.8 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 ORY13405.1 - 0.00021 20.5 0.0 0.00029 20.1 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 ORY13405.1 - 0.0021 17.5 0.0 0.0026 17.2 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Peptidase_M73 PF12389.8 ORY13405.1 - 0.084 12.7 0.1 0.13 12.1 0.1 1.2 1 0 0 1 1 1 0 Camelysin metallo-endopeptidase NmrA PF05368.13 ORY13405.1 - 0.11 12.0 0.2 0.15 11.5 0.2 1.2 1 0 0 1 1 1 0 NmrA-like family Alpha-amylase PF00128.24 ORY13406.1 - 6.7e-18 65.3 0.8 1.8e-17 64.0 0.8 1.7 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.11 ORY13406.1 - 4.7e-16 59.2 0.1 8.9e-16 58.3 0.1 1.4 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 ORY13406.1 - 6.3e-07 29.1 0.0 1.2e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 SesA PF17107.5 ORY13409.1 - 0.0019 18.4 0.1 0.0027 17.9 0.1 1.2 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases PLU-1 PF08429.11 ORY13409.1 - 0.0074 15.5 0.4 0.01 15.1 0.4 1.1 1 0 0 1 1 1 1 PLU-1-like protein DUF3107 PF11305.8 ORY13409.1 - 0.023 14.9 0.0 0.055 13.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3107) Helo_like_N PF17111.5 ORY13409.1 - 0.062 12.7 0.1 0.11 11.9 0.1 1.4 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins Trimer_CC PF08954.11 ORY13409.1 - 0.15 11.7 1.9 4 7.1 0.0 2.6 3 0 0 3 3 3 0 Trimerisation motif Alpha-amylase PF00128.24 ORY13410.1 - 2.7e-49 168.6 0.0 4.6e-49 167.8 0.0 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.18 ORY13410.1 - 0.1 13.1 0.0 0.47 11.0 0.0 2.2 2 0 0 2 2 2 0 Alpha amylase, C-terminal all-beta domain Malt_amylase_C PF16657.5 ORY13410.1 - 0.13 12.4 0.0 1.5 9.0 0.0 2.6 3 0 0 3 3 3 0 Maltogenic Amylase, C-terminal domain MFS_1 PF07690.16 ORY13411.1 - 4.4e-34 118.0 40.5 1.1e-32 113.4 13.3 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY13411.1 - 7.8e-12 44.8 21.2 1.1e-11 44.3 21.2 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 ORY13411.1 - 6.6e-07 28.1 2.4 6.6e-07 28.1 2.4 1.6 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Coagulin PF02035.15 ORY13411.1 - 0.025 14.5 0.0 0.045 13.6 0.0 1.5 1 0 0 1 1 1 0 Coagulin SET PF00856.28 ORY13412.1 - 1.5e-08 35.2 0.1 7e-08 33.0 0.1 2.0 1 1 0 1 1 1 1 SET domain adh_short PF00106.25 ORY13413.1 - 1.7e-22 79.9 0.1 5.1e-21 75.0 0.1 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY13413.1 - 3.3e-14 53.0 0.0 3.1e-13 49.8 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase GDP_Man_Dehyd PF16363.5 ORY13413.1 - 7.8e-07 28.8 0.0 1.5e-06 27.9 0.0 1.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 ORY13413.1 - 1.5e-06 27.9 0.0 2.6e-06 27.1 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 ORY13413.1 - 0.00058 19.8 0.0 0.00083 19.3 0.0 1.2 1 0 0 1 1 1 1 KR domain Methyltransf_16 PF10294.9 ORY13414.1 - 3.4e-17 62.7 0.0 5.5e-17 62.1 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_25 PF13649.6 ORY13414.1 - 2.2e-07 31.5 0.0 5.1e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY13414.1 - 0.00011 22.9 0.0 0.00027 21.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ORY13414.1 - 0.00012 21.7 0.0 0.00055 19.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 ORY13414.1 - 0.0012 18.7 0.0 0.0019 18.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY13414.1 - 0.0014 18.5 0.0 0.0025 17.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY13414.1 - 0.0023 18.6 0.0 0.0047 17.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain DUF938 PF06080.12 ORY13414.1 - 0.015 15.0 0.0 0.025 14.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) PrmA PF06325.13 ORY13414.1 - 0.035 13.5 0.0 0.069 12.5 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) CENP-B_dimeris PF09026.10 ORY13415.1 - 0.18 12.2 2.2 0.62 10.5 2.2 1.9 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Melibiase_2 PF16499.5 ORY13416.1 - 6.6e-53 179.7 5.6 4.7e-36 124.4 1.6 2.3 1 1 1 2 2 2 2 Alpha galactosidase A Melibiase_C PF17801.1 ORY13416.1 - 2e-12 47.0 0.2 1.8e-10 40.7 0.0 2.6 2 0 0 2 2 2 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 ORY13416.1 - 1.9e-05 23.8 0.0 3.4e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Melibiase EBP PF05241.12 ORY13417.1 - 3.8e-59 199.1 9.8 4.6e-59 198.9 9.8 1.0 1 0 0 1 1 1 1 Emopamil binding protein ATG27 PF09451.10 ORY13418.1 - 2e-84 283.6 0.0 2.4e-84 283.3 0.0 1.0 1 0 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.18 ORY13418.1 - 0.076 13.1 0.3 9 6.4 0.1 3.0 3 0 0 3 3 3 0 Cation-independent mannose-6-phosphate receptor repeat ADH_zinc_N PF00107.26 ORY13420.1 - 5.2e-11 42.6 0.0 8.9e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ORY13420.1 - 3.3e-07 30.1 0.0 8.4e-07 28.9 0.0 1.5 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 ORY13420.1 - 1.5e-05 26.0 0.1 0.00015 22.9 0.1 2.5 2 1 0 2 2 2 1 Zinc-binding dehydrogenase Epimerase PF01370.21 ORY13420.1 - 0.0058 16.1 0.0 0.0087 15.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 ORY13420.1 - 0.13 11.4 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain PAC4 PF16093.5 ORY13421.1 - 3.9e-23 81.4 0.2 6.1e-23 80.8 0.2 1.3 1 0 0 1 1 1 1 Proteasome assembly chaperone 4 N2227 PF07942.12 ORY13422.1 - 7.2e-88 294.3 0.0 8.8e-88 294.0 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein MtrH PF02007.18 ORY13422.1 - 0.11 11.6 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase MtrH subunit Amidase PF01425.21 ORY13423.1 - 6.3e-104 348.4 0.0 8.2e-104 348.1 0.0 1.1 1 0 0 1 1 1 1 Amidase Lactamase_B_4 PF13691.6 ORY13424.1 - 3.7e-23 81.0 0.2 9e-23 79.7 0.2 1.7 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B_2 PF12706.7 ORY13424.1 - 7.9e-10 38.6 0.1 1.3e-05 24.8 0.0 3.1 3 1 1 4 4 4 2 Beta-lactamase superfamily domain Lactamase_B PF00753.27 ORY13424.1 - 0.00021 21.4 0.0 0.00057 19.9 0.0 1.7 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily bZIP_1 PF00170.21 ORY13425.1 - 2.4e-07 30.8 10.5 2.4e-07 30.8 10.5 2.4 3 0 0 3 3 3 1 bZIP transcription factor TFIIA PF03153.13 ORY13425.1 - 0.00043 20.4 20.3 0.00071 19.7 20.3 1.4 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit bZIP_2 PF07716.15 ORY13425.1 - 0.0018 18.3 9.1 0.0018 18.3 9.1 3.2 3 0 0 3 3 3 1 Basic region leucine zipper Spt20 PF12090.8 ORY13425.1 - 0.6 9.7 16.6 1.1 8.9 16.6 1.4 1 0 0 1 1 1 0 Spt20 family FAM76 PF16046.5 ORY13425.1 - 0.69 9.2 21.3 1 8.6 21.3 1.1 1 0 0 1 1 1 0 FAM76 protein Androgen_recep PF02166.16 ORY13425.1 - 2.5 6.8 20.5 4.9 5.9 20.5 1.4 1 0 0 1 1 1 0 Androgen receptor Ank_2 PF12796.7 ORY13427.1 - 5e-08 33.4 0.2 0.0018 18.8 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ORY13427.1 - 2.2e-07 31.0 0.0 0.0088 16.3 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeats (many copies) NACHT PF05729.12 ORY13427.1 - 5.8e-05 23.1 0.0 0.00024 21.1 0.0 2.0 1 1 0 1 1 1 1 NACHT domain Ank_4 PF13637.6 ORY13427.1 - 0.00018 22.0 0.0 0.46 11.1 0.0 3.2 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Abhydrolase_6 PF12697.7 ORY13427.1 - 0.00033 21.3 0.0 0.00066 20.4 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ank_3 PF13606.6 ORY13427.1 - 0.00046 20.4 0.3 1 10.1 0.0 4.1 3 0 0 3 3 3 1 Ankyrin repeat AAA_16 PF13191.6 ORY13427.1 - 0.00082 19.8 0.0 0.0042 17.5 0.0 2.2 1 0 0 1 1 1 1 AAA ATPase domain Hydrolase_4 PF12146.8 ORY13427.1 - 0.009 15.3 0.0 0.02 14.2 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 AAA_22 PF13401.6 ORY13427.1 - 0.1 12.8 0.0 0.53 10.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain Ank PF00023.30 ORY13427.1 - 0.14 12.7 3.2 47 4.7 0.0 4.3 4 0 0 4 4 3 0 Ankyrin repeat LIDHydrolase PF10230.9 ORY13427.1 - 0.19 11.3 0.0 0.36 10.4 0.0 1.4 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Phage_holin_3_6 PF07332.11 ORY13428.1 - 2.6 8.1 7.9 4 7.5 7.9 1.2 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III PPR_2 PF13041.6 ORY13429.1 - 4.6e-28 97.2 1.8 2e-12 47.1 0.0 5.8 4 2 3 7 7 7 5 PPR repeat family PPR_3 PF13812.6 ORY13429.1 - 7.6e-20 70.8 0.0 1e-08 35.1 0.0 5.8 4 2 1 5 5 5 4 Pentatricopeptide repeat domain PPR PF01535.20 ORY13429.1 - 1.4e-15 56.4 3.9 0.01 16.0 0.0 8.6 9 0 0 9 9 9 4 PPR repeat PPR_long PF17177.4 ORY13429.1 - 3.9e-13 49.3 0.5 0.005 16.2 0.0 4.3 3 1 1 4 4 4 4 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 ORY13429.1 - 9.8e-11 41.2 1.5 0.00024 20.7 0.0 5.4 7 0 0 7 7 7 2 PPR repeat TPR_14 PF13428.6 ORY13429.1 - 0.0012 19.5 2.5 1.3 10.0 0.1 4.3 3 0 0 3 3 3 1 Tetratricopeptide repeat MRP-S27 PF10037.9 ORY13429.1 - 0.21 10.4 0.0 16 4.2 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S27 His_Phos_2 PF00328.22 ORY13430.1 - 4.9e-15 55.8 0.0 1.6e-14 54.1 0.0 1.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) TAF4 PF05236.14 ORY13431.1 - 1e-34 120.6 0.5 6.4e-33 114.7 0.5 2.8 1 1 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family CPSF73-100_C PF11718.8 ORY13432.1 - 1.2e-76 257.0 0.0 1.7e-76 256.5 0.0 1.2 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 ORY13432.1 - 6.4e-32 110.1 0.0 1.3e-31 109.2 0.0 1.5 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.27 ORY13432.1 - 1.6e-20 73.9 0.5 4.2e-20 72.6 0.5 1.7 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 ORY13432.1 - 1.4e-16 60.5 0.1 2.4e-16 59.8 0.1 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain RMMBL PF07521.12 ORY13432.1 - 9.8e-13 47.8 0.0 2.1e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 ORY13432.1 - 8e-05 22.2 0.5 0.00041 19.9 0.2 2.2 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 ORY13432.1 - 0.00086 19.2 0.0 0.0026 17.7 0.0 1.8 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Acetyltransf_7 PF13508.7 ORY13433.1 - 0.00067 20.0 0.0 0.0014 19.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORY13433.1 - 0.0049 17.1 0.0 0.0097 16.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 ORY13433.1 - 0.013 15.6 0.4 1.3 9.2 0.1 3.0 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ORY13433.1 - 0.033 14.1 0.0 0.06 13.3 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Arf PF00025.21 ORY13434.1 - 6.8e-63 211.3 1.3 8.4e-63 211.0 1.3 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 ORY13434.1 - 7.7e-13 48.7 0.1 1.1e-12 48.2 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 ORY13434.1 - 3.2e-12 46.3 1.4 4.3e-07 29.4 0.2 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 ORY13434.1 - 9.7e-12 44.8 0.0 1.2e-11 44.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 ORY13434.1 - 5.3e-10 39.1 0.1 6.7e-10 38.7 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 ORY13434.1 - 2.9e-08 33.8 0.0 4e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 ORY13434.1 - 2.1e-07 30.6 0.0 2.7e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 ORY13434.1 - 1.1e-05 25.1 0.0 0.00023 20.8 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 ORY13434.1 - 0.031 13.8 0.4 0.084 12.4 0.4 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B 6PF2K PF01591.18 ORY13434.1 - 0.086 12.1 0.0 0.24 10.7 0.0 1.7 2 0 0 2 2 2 0 6-phosphofructo-2-kinase CdhD PF03599.16 ORY13434.1 - 0.086 11.5 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase delta subunit NTPase_1 PF03266.15 ORY13434.1 - 0.12 12.3 0.1 0.3 11.0 0.1 1.6 1 1 0 1 1 1 0 NTPase DUF4045 PF13254.6 ORY13435.1 - 1.6e-117 393.7 45.8 1.6e-117 393.7 45.8 5.5 3 2 1 4 4 4 1 Domain of unknown function (DUF4045) Gelsolin PF00626.22 ORY13435.1 - 1.1e-09 38.1 0.0 0.021 14.7 0.0 4.1 4 0 0 4 4 4 3 Gelsolin repeat Tmemb_cc2 PF10267.9 ORY13435.1 - 0.71 8.9 6.4 3.4 6.7 0.1 2.7 2 1 0 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein Glyco_hydro_61 PF03443.14 ORY13436.1 - 3e-64 216.8 0.9 3.6e-64 216.5 0.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CSD PF00313.22 ORY13436.1 - 0.008 16.0 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain HSP70 PF00012.20 ORY13437.1 - 2.2e-11 42.7 0.3 1e-09 37.2 0.1 2.0 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 ORY13437.1 - 0.034 13.0 0.1 0.2 10.4 0.0 1.9 2 0 0 2 2 2 0 MreB/Mbl protein PAN_4 PF14295.6 ORY13438.1 - 0.0042 16.9 0.4 0.094 12.6 0.1 2.4 2 0 0 2 2 2 1 PAN domain Cellulase PF00150.18 ORY13439.1 - 8.2e-25 87.8 0.1 1.5e-24 86.9 0.1 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Zn_clus PF00172.18 ORY13440.1 - 2.2e-07 30.9 11.1 4e-07 30.0 11.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.24 ORY13441.1 - 6.4e-62 209.9 28.0 1.4e-61 208.8 28.0 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY13441.1 - 5.8e-16 58.3 32.6 5.8e-16 58.3 32.6 2.7 1 1 1 3 3 3 1 Major Facilitator Superfamily RXT2_N PF08595.11 ORY13457.1 - 2.7e-29 102.2 0.8 6.9e-29 100.9 0.0 2.1 2 0 0 2 2 2 1 RXT2-like, N-terminal Lsm_interact PF05391.11 ORY13457.1 - 7.4 6.2 6.3 18 5.0 1.8 2.6 2 0 0 2 2 2 0 Lsm interaction motif Gryzun PF07919.12 ORY13458.1 - 8.6e-189 629.1 0.0 1.1e-188 628.8 0.0 1.1 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi Foie-gras_1 PF11817.8 ORY13458.1 - 3.4e-95 318.5 0.9 5.7e-87 291.6 1.3 2.2 2 0 0 2 2 2 2 Foie gras liver health family 1 Mito_carr PF00153.27 ORY13459.1 - 2.2e-51 171.7 3.0 3.9e-18 65.1 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein FlaC_arch PF05377.11 ORY13460.1 - 0.099 13.1 0.2 0.39 11.1 0.2 2.0 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) HTH_20 PF12840.7 ORY13460.1 - 0.11 12.6 0.0 1.1 9.4 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain Pkinase PF00069.25 ORY13461.1 - 1.9e-13 50.4 0.0 4.1e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Ank_2 PF12796.7 ORY13461.1 - 8.8e-12 45.5 0.1 0.0077 16.8 0.0 4.5 3 1 1 4 4 4 4 Ankyrin repeats (3 copies) Pkinase_Tyr PF07714.17 ORY13461.1 - 4.2e-07 29.5 0.0 6.3e-06 25.7 0.0 2.6 1 1 0 1 1 1 1 Protein tyrosine kinase Ank_3 PF13606.6 ORY13461.1 - 1e-06 28.6 0.0 2.3 9.0 0.0 6.3 6 0 0 6 6 6 1 Ankyrin repeat Ank_4 PF13637.6 ORY13461.1 - 3.2e-06 27.6 0.1 1.5 9.5 0.1 5.0 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 ORY13461.1 - 1.6e-05 25.1 0.0 13 6.3 0.0 5.0 3 1 1 4 4 4 1 Ankyrin repeats (many copies) Pox_ser-thr_kin PF05445.11 ORY13461.1 - 0.18 10.7 0.0 0.28 10.1 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Voltage_CLC PF00654.20 ORY13464.1 - 9.4e-89 298.1 21.1 9.4e-89 298.1 21.1 1.9 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 ORY13464.1 - 0.012 16.0 0.0 0.03 14.8 0.0 1.7 1 0 0 1 1 1 0 CBS domain Myc-LZ PF02344.15 ORY13464.1 - 0.41 10.8 2.0 0.58 10.3 0.8 1.9 2 0 0 2 2 2 0 Myc leucine zipper domain Kelch_5 PF13854.6 ORY13465.1 - 1e-06 28.5 0.1 0.057 13.4 0.0 3.8 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.6 ORY13465.1 - 0.00018 21.7 1.4 7.7 7.0 0.0 5.2 5 0 0 5 5 5 1 Kelch motif Kelch_4 PF13418.6 ORY13465.1 - 0.0013 18.7 4.2 4.3 7.4 0.0 4.9 6 0 0 6 6 6 1 Galactose oxidase, central domain RIFIN PF02009.16 ORY13465.1 - 0.0034 17.3 0.0 0.0049 16.8 0.0 1.2 1 0 0 1 1 1 1 Rifin NDUF_B4 PF07225.12 ORY13465.1 - 0.066 13.1 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) TrbC PF04956.13 ORY13465.1 - 0.21 11.8 1.1 0.44 10.8 1.1 1.4 1 0 0 1 1 1 0 TrbC/VIRB2 family MGC-24 PF05283.11 ORY13465.1 - 0.67 10.4 4.4 0.32 11.5 0.8 2.3 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin CHORD PF04968.12 ORY13468.1 - 2.5e-50 169.1 22.3 8.8e-26 90.4 8.3 2.3 2 0 0 2 2 2 2 CHORD CS PF04969.16 ORY13468.1 - 1.7e-11 45.0 0.1 2.5e-11 44.4 0.1 1.3 1 0 0 1 1 1 1 CS domain BTK PF00779.19 ORY13468.1 - 2.5 8.0 12.9 6.2 6.7 1.1 3.1 2 1 0 2 2 2 0 BTK motif DUF836 PF05768.14 ORY13469.1 - 4.3e-14 52.7 0.0 5e-14 52.5 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.24 ORY13469.1 - 0.0032 17.6 0.0 0.0054 16.9 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin HpcH_HpaI PF03328.14 ORY13470.1 - 6.2e-30 104.0 0.0 8.3e-30 103.6 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family FMN_red PF03358.15 ORY13470.1 - 0.012 15.4 0.0 0.024 14.4 0.0 1.5 1 0 0 1 1 1 0 NADPH-dependent FMN reductase DUF2156 PF09924.9 ORY13470.1 - 0.028 13.4 0.0 0.043 12.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2156) DSPc PF00782.20 ORY13470.1 - 0.076 12.8 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain 14-3-3 PF00244.20 ORY13471.1 - 9.2e-08 31.9 0.0 1.6e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 14-3-3 protein MFS_1 PF07690.16 ORY13473.1 - 2.4e-42 145.1 84.4 4.1e-39 134.5 53.9 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 ORY13473.1 - 0.017 13.4 19.3 0.11 10.8 17.2 2.9 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family dbPDZ_assoc PF16610.5 ORY13473.1 - 0.58 10.4 3.8 1.2 9.4 3.8 1.5 1 0 0 1 1 1 0 Unstructured region between two PDZ domains on Dlg5 Dfp1_Him1_M PF08630.10 ORY13473.1 - 1.6 9.0 4.8 6.4 7.0 0.4 2.2 1 1 1 2 2 2 0 Dfp1/Him1, central region Nop PF01798.18 ORY13474.1 - 3.6e-70 236.0 0.0 4.8e-70 235.6 0.0 1.2 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 ORY13474.1 - 1.9e-45 154.6 1.9 4.2e-45 153.6 1.9 1.6 1 0 0 1 1 1 1 Prp31 C terminal domain TPR_14 PF13428.6 ORY13475.1 - 7.6e-24 82.4 26.9 0.0029 18.3 0.2 12.1 7 3 8 15 15 15 7 Tetratricopeptide repeat HAT PF02184.16 ORY13475.1 - 3.5e-23 81.2 83.1 1e-12 47.7 4.8 15.3 15 1 0 15 15 15 6 HAT (Half-A-TPR) repeat TPR_19 PF14559.6 ORY13475.1 - 4.4e-20 72.0 0.8 3.6e-05 24.2 0.0 7.1 5 2 0 7 7 7 4 Tetratricopeptide repeat Suf PF05843.14 ORY13475.1 - 1.2e-17 64.9 26.0 0.00021 21.4 4.3 6.6 2 1 2 5 5 5 4 Suppressor of forked protein (Suf) TPR_17 PF13431.6 ORY13475.1 - 6.1e-09 35.7 2.6 0.0025 18.1 0.1 5.6 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_15 PF13429.6 ORY13475.1 - 1.2e-05 24.7 16.0 0.57 9.3 0.1 5.4 2 1 2 5 5 5 3 Tetratricopeptide repeat NRDE-2 PF08424.10 ORY13475.1 - 0.0032 16.7 31.7 0.069 12.3 0.1 6.7 3 2 2 6 6 6 4 NRDE-2, necessary for RNA interference TPR_2 PF07719.17 ORY13475.1 - 0.0034 17.4 20.9 1.1 9.5 0.0 9.1 11 0 0 11 11 11 1 Tetratricopeptide repeat TPR_8 PF13181.6 ORY13475.1 - 0.0045 17.1 14.4 9.2 6.8 0.0 8.0 10 0 0 10 10 9 1 Tetratricopeptide repeat TPR_16 PF13432.6 ORY13475.1 - 0.0051 17.4 5.7 17 6.1 0.0 7.2 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_6 PF13174.6 ORY13475.1 - 0.0062 17.1 18.5 11 6.9 0.1 8.3 10 0 0 10 10 9 1 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY13475.1 - 0.094 12.9 1.8 6.8 7.0 0.0 3.9 5 0 0 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 ORY13475.1 - 0.19 12.0 18.4 6.7 7.1 0.0 7.0 9 0 0 9 9 8 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 ORY13475.1 - 0.25 11.4 6.7 2.1 8.5 0.0 4.5 6 0 0 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat U3_assoc_6 PF08640.11 ORY13475.1 - 0.8 9.8 28.9 0.049 13.7 2.6 7.1 6 2 2 8 8 8 0 U3 small nucleolar RNA-associated protein 6 2-Hacid_dh_C PF02826.19 ORY13476.1 - 6.1e-53 178.8 0.0 8e-53 178.4 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 ORY13476.1 - 1.4e-20 73.4 0.0 1.9e-20 72.9 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 ORY13476.1 - 0.032 14.4 0.1 0.049 13.8 0.1 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Zn_clus PF00172.18 ORY13478.1 - 3.6e-08 33.4 9.6 6.5e-08 32.6 9.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mito_carr PF00153.27 ORY13479.1 - 5.3e-39 132.0 7.9 3.2e-16 59.0 1.0 4.6 3 2 0 3 3 3 3 Mitochondrial carrier protein SLATT_fungal PF18142.1 ORY13480.1 - 6.1e-22 77.8 0.1 7.3e-22 77.6 0.1 1.1 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain Phage_holin_3_6 PF07332.11 ORY13480.1 - 0.0018 18.3 0.1 0.0025 17.9 0.1 1.2 1 0 0 1 1 1 1 Putative Actinobacterial Holin-X, holin superfamily III SpoVAB PF13782.6 ORY13480.1 - 0.0074 16.6 0.5 0.011 16.1 0.5 1.1 1 0 0 1 1 1 1 Stage V sporulation protein AB RGS-like PF09128.11 ORY13481.1 - 0.082 12.6 1.6 0.099 12.3 1.6 1.1 1 0 0 1 1 1 0 Regulator of G protein signalling-like domain DUF4452 PF14618.6 ORY13482.1 - 3.1e-72 241.9 13.3 3.8e-72 241.7 13.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4452) Cyclin_N PF00134.23 ORY13483.1 - 2.8e-14 52.9 2.7 7.9e-11 41.8 0.4 2.8 2 1 0 3 3 3 2 Cyclin, N-terminal domain Cyclin_C_2 PF16899.5 ORY13483.1 - 0.019 15.4 0.4 0.06 13.7 0.4 1.8 1 0 0 1 1 1 0 Cyclin C-terminal domain TFIIB PF00382.19 ORY13483.1 - 0.022 14.8 0.5 0.058 13.5 0.5 1.8 1 1 0 1 1 1 0 Transcription factor TFIIB repeat Mito_carr PF00153.27 ORY13484.1 - 3.9e-65 215.8 5.4 1.2e-22 79.6 0.2 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 ORY13484.1 - 1.1e-21 77.0 2.7 1.3e-10 41.6 0.7 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 ORY13484.1 - 2.2e-21 73.7 6.6 6.8e-06 25.3 0.7 4.4 4 0 0 4 4 4 3 EF hand EF-hand_5 PF13202.6 ORY13484.1 - 1.5e-18 65.4 9.2 6.6e-06 25.4 1.1 3.5 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 ORY13484.1 - 3.9e-17 60.6 10.6 1.7e-05 24.4 0.2 4.6 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 ORY13484.1 - 4.3e-14 52.1 2.8 4.5e-07 29.6 0.1 3.2 1 1 2 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 ORY13484.1 - 2.8e-07 30.9 0.1 0.00065 20.0 0.0 2.3 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 ORY13484.1 - 0.16 12.0 2.0 12 6.0 0.1 3.1 1 1 2 3 3 3 0 Cytoskeletal-regulatory complex EF hand Cpn10 PF00166.21 ORY13485.1 - 2.1e-28 98.2 0.0 2.3e-28 98.1 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit ATP_bind_3 PF01171.20 ORY13486.1 - 1.9e-35 122.3 0.0 2.8e-35 121.7 0.0 1.3 1 0 0 1 1 1 1 PP-loop family HET PF06985.11 ORY13489.1 - 3.7e-29 101.9 0.2 6.6e-29 101.2 0.2 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HET PF06985.11 ORY13491.1 - 0.00023 21.6 1.6 0.11 12.8 0.2 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) bZIP_1 PF00170.21 ORY13492.1 - 1.8e-06 28.0 1.1 3e-06 27.2 1.1 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 ORY13492.1 - 3.5e-06 27.0 2.7 6.5e-06 26.1 2.7 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 ORY13492.1 - 0.0047 17.4 1.3 0.009 16.5 1.3 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor DivIC PF04977.15 ORY13492.1 - 0.027 14.2 0.7 0.044 13.6 0.7 1.3 1 0 0 1 1 1 0 Septum formation initiator Rbsn PF11464.8 ORY13492.1 - 0.081 12.7 0.3 0.13 12.0 0.3 1.3 1 0 0 1 1 1 0 Rabenosyn Rab binding domain Zn_clus PF00172.18 ORY13494.1 - 1.9e-10 40.7 9.5 1.9e-10 40.7 9.5 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ThiS PF02597.20 ORY13494.1 - 0.12 13.1 0.1 3.2 8.5 0.0 2.7 2 1 1 3 3 3 0 ThiS family CIA30 PF08547.12 ORY13495.1 - 3.8e-37 127.8 0.1 4.8e-37 127.4 0.1 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) DUF202 PF02656.15 ORY13496.1 - 4.8e-17 62.2 3.5 9.5e-17 61.2 0.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) CitMHS PF03600.16 ORY13496.1 - 0.39 9.9 4.8 0.48 9.6 4.8 1.1 1 0 0 1 1 1 0 Citrate transporter COX4_pro_2 PF07835.12 ORY13496.1 - 0.43 10.7 0.0 0.43 10.7 0.0 2.7 3 0 0 3 3 3 0 Bacterial aa3 type cytochrome c oxidase subunit IV DUF2189 PF09955.9 ORY13496.1 - 0.71 10.1 6.7 0.35 11.1 3.4 1.8 2 0 0 2 2 2 0 Predicted integral membrane protein (DUF2189) DUF4231 PF14015.6 ORY13496.1 - 1.7 9.2 6.0 0.62 10.6 0.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4231) DUF3112 PF11309.8 ORY13496.1 - 2.2 7.7 8.1 1.6 8.1 0.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3112) RPA_C PF08784.11 ORY13497.1 - 1.3e-15 58.0 0.1 2.2e-15 57.2 0.1 1.4 1 0 0 1 1 1 1 Replication protein A C terminal tRNA_anti-codon PF01336.25 ORY13497.1 - 2.1e-08 34.0 0.0 4e-08 33.1 0.0 1.5 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain HIN PF02760.15 ORY13497.1 - 0.11 12.2 0.1 0.16 11.7 0.1 1.2 1 0 0 1 1 1 0 HIN-200/IF120x domain DEAD PF00270.29 ORY13498.1 - 8.5e-49 165.7 0.1 2.1e-48 164.4 0.1 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY13498.1 - 1.8e-24 86.2 0.0 6e-24 84.5 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 ORY13498.1 - 9.6e-22 77.0 4.0 3.2e-21 75.3 4.0 2.0 1 0 0 1 1 1 1 DBP10CT (NUC160) domain Zn_clus PF00172.18 ORY13500.1 - 0.00021 21.4 11.9 0.00031 20.8 11.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DnaJ PF00226.31 ORY13502.1 - 2.9e-14 52.9 0.0 8e-14 51.5 0.0 1.8 1 0 0 1 1 1 1 DnaJ domain Acyl-ACP_TE PF01643.17 ORY13502.1 - 0.0045 16.3 5.6 0.0066 15.8 5.6 1.3 1 0 0 1 1 1 1 Acyl-ACP thioesterase TP_methylase PF00590.20 ORY13502.1 - 2 8.3 4.4 5 7.0 4.4 1.7 1 1 0 1 1 1 0 Tetrapyrrole (Corrin/Porphyrin) Methylases DEAD PF00270.29 ORY13503.1 - 3.4e-47 160.5 0.0 6.8e-47 159.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY13503.1 - 5.6e-24 84.6 0.0 2.1e-23 82.7 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 ORY13503.1 - 2e-17 63.2 0.1 5.3e-17 61.8 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 ORY13503.1 - 5.6e-06 26.5 0.5 2.3e-05 24.4 0.0 2.3 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 ORY13503.1 - 0.0043 16.4 0.0 0.0043 16.4 0.0 4.9 5 0 0 5 5 5 1 U3-containing 90S pre-ribosomal complex subunit ERCC3_RAD25_C PF16203.5 ORY13503.1 - 0.045 12.9 0.0 0.097 11.9 0.0 1.5 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase PAS_11 PF14598.6 ORY13503.1 - 0.064 13.4 0.1 0.19 11.8 0.0 1.8 2 0 0 2 2 2 0 PAS domain F-box-like PF12937.7 ORY13504.1 - 3e-05 23.8 0.1 0.0006 19.7 0.0 2.7 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 ORY13504.1 - 0.026 14.4 0.0 1.3 9.0 0.0 2.5 2 0 0 2 2 2 0 F-box domain F-box_4 PF15966.5 ORY13504.1 - 0.026 14.4 0.0 0.096 12.6 0.0 1.9 2 0 0 2 2 2 0 F-box Rad10 PF03834.14 ORY13505.1 - 1.2e-47 160.6 0.0 1.7e-47 160.1 0.0 1.2 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.6 ORY13505.1 - 0.0032 18.0 0.0 0.0069 17.0 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain Rox3 PF08633.10 ORY13506.1 - 6.9e-51 173.5 0.9 1.1e-50 172.7 0.1 1.7 2 0 0 2 2 2 1 Rox3 mediator complex subunit zf-C2H2_4 PF13894.6 ORY13508.1 - 0.017 15.9 11.3 1.8 9.6 5.5 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger DUF865 PF05906.11 ORY13508.1 - 2 8.3 6.4 14 5.6 0.9 3.0 2 0 0 2 2 2 0 Herpesvirus-7 repeat of unknown function (DUF865) zf-C2H2 PF00096.26 ORY13508.1 - 4.3 8.0 15.6 5.8 7.6 4.0 3.2 2 1 0 2 2 2 0 Zinc finger, C2H2 type Astacin PF01400.24 ORY13509.1 - 0.035 13.7 0.1 0.073 12.7 0.0 1.6 2 0 0 2 2 2 0 Astacin (Peptidase family M12A) Death PF00531.22 ORY13509.1 - 0.095 12.9 0.0 1.7 8.8 0.0 2.3 2 0 0 2 2 2 0 Death domain zf-H2C2_2 PF13465.6 ORY13510.1 - 0.00024 21.4 0.4 0.0017 18.7 0.0 2.7 2 0 0 2 2 2 1 Zinc-finger double domain Striatin PF08232.12 ORY13510.1 - 0.027 15.1 0.5 0.068 13.8 0.5 1.6 1 0 0 1 1 1 0 Striatin family zf-C2H2 PF00096.26 ORY13510.1 - 0.15 12.6 0.1 0.15 12.6 0.1 4.0 3 1 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 ORY13511.1 - 0.096 12.7 1.3 0.22 11.5 1.3 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_4 PF13894.6 ORY13511.1 - 3.3 8.8 8.1 0.86 10.6 3.8 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-RING_5 PF14634.6 ORY13512.1 - 1.8e-07 31.0 10.3 3e-07 30.3 10.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 ORY13512.1 - 0.00022 21.0 6.8 0.00042 20.1 6.8 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 APG6_N PF17675.1 ORY13512.1 - 0.00037 21.0 4.7 0.00055 20.5 4.7 1.2 1 0 0 1 1 1 1 Apg6 coiled-coil region zf-C3HC4_2 PF13923.6 ORY13512.1 - 0.0011 18.8 8.2 0.003 17.4 8.2 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Atg14 PF10186.9 ORY13512.1 - 0.0023 17.1 0.3 0.0025 17.0 0.3 1.2 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 SKA2 PF16740.5 ORY13512.1 - 0.0051 16.6 11.3 0.084 12.7 7.4 2.2 1 1 1 2 2 2 1 Spindle and kinetochore-associated protein 2 GAS PF13851.6 ORY13512.1 - 0.0059 16.0 7.9 0.0074 15.7 7.9 1.1 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding zf-C3HC4 PF00097.25 ORY13512.1 - 0.0092 15.8 11.0 0.017 15.0 11.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DASH_Spc34 PF08657.10 ORY13512.1 - 0.015 15.1 2.1 0.019 14.8 2.1 1.1 1 0 0 1 1 1 0 DASH complex subunit Spc34 Lebercilin PF15619.6 ORY13512.1 - 0.017 14.8 8.2 0.024 14.3 8.2 1.2 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease YabA PF06156.13 ORY13512.1 - 0.018 15.7 5.0 0.03 15.0 5.0 1.4 1 0 0 1 1 1 0 Initiation control protein YabA Prok-RING_1 PF14446.6 ORY13512.1 - 0.023 14.6 0.0 0.023 14.6 0.0 2.4 2 1 0 2 2 1 0 Prokaryotic RING finger family 1 IcmF-related PF06761.12 ORY13512.1 - 0.024 14.1 4.3 0.03 13.8 4.3 1.1 1 0 0 1 1 1 0 Intracellular multiplication and human macrophage-killing Mito_carr PF00153.27 ORY13512.1 - 0.03 14.2 0.1 4.2 7.3 0.0 2.3 2 0 0 2 2 2 0 Mitochondrial carrier protein zf-RING_2 PF13639.6 ORY13512.1 - 0.03 14.6 8.3 0.062 13.6 8.3 1.5 1 0 0 1 1 1 0 Ring finger domain OmpH PF03938.14 ORY13512.1 - 0.044 14.1 15.2 0.062 13.6 15.2 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Phage_Mu_Gam PF07352.12 ORY13512.1 - 0.047 13.6 6.9 0.063 13.2 6.9 1.2 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein zf-RING_UBOX PF13445.6 ORY13512.1 - 0.051 13.6 6.9 0.12 12.4 6.9 1.7 1 0 0 1 1 1 0 RING-type zinc-finger ATG16 PF08614.11 ORY13512.1 - 0.052 13.8 11.1 0.095 12.9 11.1 1.4 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF4407 PF14362.6 ORY13512.1 - 0.068 12.5 4.7 0.09 12.1 4.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) UPF0242 PF06785.11 ORY13512.1 - 0.072 13.2 6.2 0.094 12.8 6.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DivIC PF04977.15 ORY13512.1 - 0.074 12.8 14.4 0.71 9.7 6.7 2.6 1 1 1 2 2 2 0 Septum formation initiator DUF948 PF06103.11 ORY13512.1 - 0.078 13.2 2.7 0.092 13.0 1.1 1.9 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) FKBP_N PF01346.18 ORY13512.1 - 0.092 13.7 4.1 0.15 13.1 4.1 1.4 1 0 0 1 1 1 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase IFT57 PF10498.9 ORY13512.1 - 0.093 11.7 8.6 0.13 11.2 8.6 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Spc24 PF08286.11 ORY13512.1 - 0.11 12.8 5.4 0.14 12.4 5.1 1.4 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 Mce4_CUP1 PF11887.8 ORY13512.1 - 0.12 11.8 1.7 0.17 11.3 1.7 1.2 1 0 0 1 1 1 0 Cholesterol uptake porter CUP1 of Mce4, putative LUC7 PF03194.15 ORY13512.1 - 0.14 11.8 7.5 0.19 11.3 7.5 1.2 1 0 0 1 1 1 0 LUC7 N_terminus FapA PF03961.13 ORY13512.1 - 0.14 10.7 3.3 0.18 10.4 3.3 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A MatP_C PF17414.2 ORY13512.1 - 0.16 12.2 3.9 0.28 11.4 0.7 2.2 1 1 1 2 2 2 0 MatP C-terminal ribbon-helix-helix domain Cnl2_NKP2 PF09447.10 ORY13512.1 - 0.18 12.0 2.8 0.87 9.8 0.0 2.3 2 0 0 2 2 2 0 Cnl2/NKP2 family protein Osmo_CC PF08946.10 ORY13512.1 - 0.21 11.8 4.5 3 8.1 4.1 2.7 1 1 1 2 2 2 0 Osmosensory transporter coiled coil FliD_N PF02465.18 ORY13512.1 - 0.24 12.1 5.2 0.36 11.6 5.2 1.4 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus TF_Zn_Ribbon PF08271.12 ORY13512.1 - 0.26 10.8 4.0 0.51 9.9 4.0 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding THOC7 PF05615.13 ORY13512.1 - 0.32 11.3 8.9 0.45 10.8 8.2 1.6 1 1 0 1 1 1 0 Tho complex subunit 7 ZapB PF06005.12 ORY13512.1 - 0.32 11.5 10.6 3.3 8.2 10.7 2.1 1 1 0 1 1 1 0 Cell division protein ZapB DUF5595 PF18077.1 ORY13512.1 - 0.36 10.9 2.5 0.31 11.1 1.1 1.6 2 0 0 2 2 1 0 Domain of unknown function (DUF5595) Syntaxin_2 PF14523.6 ORY13512.1 - 0.42 11.0 9.3 0.65 10.4 9.3 1.3 1 0 0 1 1 1 0 Syntaxin-like protein V-ATPase_G_2 PF16999.5 ORY13512.1 - 0.48 10.9 11.2 0.72 10.3 11.2 1.2 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit 60KD_IMP PF02096.20 ORY13512.1 - 0.58 10.0 10.3 0.48 10.3 5.5 2.1 1 1 1 2 2 2 0 60Kd inner membrane protein ZYG-11_interact PF05884.12 ORY13512.1 - 0.71 9.2 4.7 0.95 8.8 4.7 1.1 1 0 0 1 1 1 0 Interactor of ZYG-11 ABC_tran_CTD PF16326.5 ORY13512.1 - 1 9.7 10.0 9.8 6.5 5.9 2.3 1 1 1 2 2 2 0 ABC transporter C-terminal domain MbeD_MobD PF04899.12 ORY13512.1 - 1.2 9.2 11.0 0.66 10.1 0.2 2.3 1 1 1 2 2 2 0 MbeD/MobD like NPV_P10 PF05531.12 ORY13512.1 - 1.6 9.3 4.9 4.3 7.9 4.9 1.8 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Sec2p PF06428.11 ORY13512.1 - 2.4 8.2 11.0 1.5 8.8 4.9 2.2 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p SlyX PF04102.12 ORY13512.1 - 2.6 8.7 13.0 95 3.7 13.0 2.5 1 1 0 1 1 1 0 SlyX TMPIT PF07851.13 ORY13512.1 - 4 6.6 8.2 5.2 6.2 8.2 1.1 1 0 0 1 1 1 0 TMPIT-like protein zf-RING_6 PF14835.6 ORY13512.1 - 4.7 7.2 7.5 9.2 6.2 7.5 1.5 1 1 0 1 1 1 0 zf-RING of BARD1-type protein Cupin_8 PF13621.6 ORY13513.1 - 1.5e-28 100.2 0.0 1.9e-28 99.9 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 ORY13513.1 - 0.00065 20.1 0.0 0.0019 18.6 0.0 1.8 1 1 0 1 1 1 1 JmjC domain, hydroxylase 3-HAO PF06052.12 ORY13513.1 - 0.1 12.2 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyanthranilic acid dioxygenase Prefoldin PF02996.17 ORY13514.1 - 4.2e-22 78.3 0.0 5.3e-22 78.0 0.0 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.20 ORY13514.1 - 0.045 13.7 0.1 6.4 6.8 0.1 2.1 2 0 0 2 2 2 0 Prefoldin subunit Uds1 PF15456.6 ORY13514.1 - 0.092 12.9 0.0 0.16 12.1 0.0 1.4 1 1 0 1 1 1 0 Up-regulated During Septation Ribosomal_L23 PF00276.20 ORY13516.1 - 1.1e-06 28.9 0.1 3e-06 27.5 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L23 Vir_act_alpha_C PF10400.9 ORY13516.1 - 4.3 8.1 8.3 0.33 11.7 1.4 2.5 3 0 0 3 3 3 0 Virulence activator alpha C-term SprT-like PF10263.9 ORY13517.1 - 6.8e-20 71.0 0.0 1.2e-19 70.3 0.0 1.4 1 0 0 1 1 1 1 SprT-like family PRP21_like_P PF12230.8 ORY13517.1 - 0.017 15.0 0.0 0.026 14.4 0.0 1.2 1 0 0 1 1 1 0 Pre-mRNA splicing factor PRP21 like protein zf_UBZ PF18439.1 ORY13517.1 - 0.02 14.5 0.5 0.037 13.6 0.5 1.4 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger zf-WRNIP1_ubi PF18279.1 ORY13517.1 - 0.12 13.0 0.6 0.29 11.8 0.1 1.9 2 0 0 2 2 2 0 Werner helicase-interacting protein 1 ubiquitin-binding domain Peptidase_M91 PF14891.6 ORY13517.1 - 0.13 12.6 0.0 0.31 11.3 0.0 1.6 1 1 0 1 1 1 0 Effector protein RabGAP-TBC PF00566.18 ORY13518.1 - 6e-47 160.1 0.2 1e-46 159.3 0.2 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Porphobil_deamC PF03900.15 ORY13518.1 - 0.07 13.5 0.0 0.19 12.1 0.0 1.8 1 0 0 1 1 1 0 Porphobilinogen deaminase, C-terminal domain FAD_binding_3 PF01494.19 ORY13519.1 - 1.2e-74 251.7 0.0 1.5e-74 251.4 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 ORY13519.1 - 7.4e-38 130.2 0.0 1.5e-37 129.2 0.0 1.5 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox_2 PF07992.14 ORY13519.1 - 0.0012 18.2 0.0 0.016 14.4 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ORY13519.1 - 0.0018 17.9 0.3 0.018 14.6 0.1 2.1 1 1 1 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ORY13519.1 - 0.007 16.6 0.0 0.02 15.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain UDPG_MGDP_dh_N PF03721.14 ORY13519.1 - 0.022 14.4 0.0 0.04 13.5 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox PF00070.27 ORY13519.1 - 0.023 15.2 0.0 0.076 13.6 0.0 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 ORY13519.1 - 0.049 12.9 0.0 0.079 12.2 0.0 1.3 1 0 0 1 1 1 0 Thi4 family XdhC_C PF13478.6 ORY13519.1 - 0.055 14.0 0.0 0.1 13.1 0.0 1.4 1 0 0 1 1 1 0 XdhC Rossmann domain p450 PF00067.22 ORY13521.1 - 2.9e-50 171.4 0.0 3.9e-50 170.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_4 PF01565.23 ORY13522.1 - 4.4e-28 97.8 2.1 4.4e-28 97.8 2.1 1.6 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 ORY13522.1 - 7.9e-14 51.5 0.1 2.3e-13 50.0 0.0 1.9 2 0 0 2 2 2 1 Berberine and berberine like CFEM PF05730.11 ORY13523.1 - 3e-14 52.8 12.7 6e-14 51.9 12.7 1.5 1 0 0 1 1 1 1 CFEM domain WD40 PF00400.32 ORY13525.1 - 2.2e-47 158.0 15.1 8.1e-10 39.1 0.2 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY13525.1 - 9.6e-09 35.4 1.9 0.024 14.9 0.1 4.9 3 1 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 ORY13525.1 - 0.0082 14.9 0.0 0.65 8.7 0.0 3.0 1 1 2 3 3 3 1 Nup133 N terminal like WD40_like PF17005.5 ORY13525.1 - 0.011 15.1 0.0 0.04 13.2 0.0 1.9 2 0 0 2 2 2 0 WD40-like domain Nup160 PF11715.8 ORY13525.1 - 0.057 12.0 5.1 13 4.2 0.0 4.3 1 1 3 4 4 4 0 Nucleoporin Nup120/160 W_rich_C PF07483.11 ORY13525.1 - 0.48 10.6 4.5 0.35 11.0 0.2 2.8 3 1 1 4 4 4 0 Tryptophan-rich Synechocystis species C-terminal domain AAA PF00004.29 ORY13527.1 - 7.2e-16 58.8 0.0 2.9e-15 56.9 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_10 PF17872.1 ORY13527.1 - 6.8e-12 45.4 0.2 1.8e-11 44.1 0.2 1.6 1 0 0 1 1 1 1 AAA lid domain AAA_16 PF13191.6 ORY13527.1 - 1.5e-11 45.0 0.0 9.5e-11 42.4 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 ORY13527.1 - 3.2e-09 37.2 0.0 7.8e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain BAH PF01426.18 ORY13527.1 - 8.8e-08 32.0 0.0 2.3e-07 30.7 0.0 1.7 1 0 0 1 1 1 1 BAH domain AAA_19 PF13245.6 ORY13527.1 - 0.0016 18.8 0.0 0.0035 17.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 ORY13527.1 - 0.0074 16.1 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 ORY13527.1 - 0.014 15.6 0.0 0.045 14.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 ORY13527.1 - 0.026 14.5 0.0 0.056 13.4 0.0 1.5 1 1 0 1 1 1 0 NACHT domain AAA_30 PF13604.6 ORY13527.1 - 0.052 13.3 1.3 0.13 11.9 0.1 2.0 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 ORY13527.1 - 0.058 12.6 0.0 0.086 12.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_32 PF13654.6 ORY13527.1 - 0.078 11.7 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 ORY13527.1 - 0.092 13.3 0.0 0.17 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 ORY13527.1 - 0.12 12.2 0.0 2 8.2 0.0 2.4 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea PIF1 PF05970.14 ORY13527.1 - 0.12 11.5 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase ssDBP PF17878.1 ORY13527.1 - 0.13 12.5 0.0 0.28 11.4 0.0 1.4 1 0 0 1 1 1 0 Single-stranded DNA-binding protein bZIP_1 PF00170.21 ORY13528.1 - 0.00035 20.6 8.3 0.00057 19.9 8.3 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 ORY13528.1 - 0.0047 17.0 7.8 0.0074 16.3 7.8 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 ORY13528.1 - 0.027 15.0 3.7 0.043 14.3 3.7 1.2 1 0 0 1 1 1 0 bZIP Maf transcription factor NLRC4_HD2 PF17776.1 ORY13531.1 - 0.048 14.2 0.0 0.049 14.2 0.0 1.1 1 0 0 1 1 1 0 NLRC4 helical domain HD2 DDHD PF02862.17 ORY13533.1 - 2e-25 90.3 0.2 5.9e-16 59.3 0.0 2.8 2 1 1 3 3 3 2 DDHD domain MAJIN PF15077.6 ORY13533.1 - 0.19 11.5 0.3 0.33 10.7 0.3 1.3 1 0 0 1 1 1 0 Membrane-anchored junction protein V-set_2 PF15910.5 ORY13534.1 - 0.18 11.9 0.2 0.37 10.9 0.2 1.5 1 0 0 1 1 1 0 ICOS V-set domain zf-TRAF PF02176.18 ORY13535.1 - 0.0017 19.0 0.6 0.0034 18.0 0.6 1.5 1 0 0 1 1 1 1 TRAF-type zinc finger Ank_4 PF13637.6 ORY13536.1 - 5.2e-22 77.9 0.5 3.6e-10 40.2 0.0 2.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 ORY13536.1 - 1.9e-16 59.7 1.7 2.9e-05 24.3 0.1 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.7 ORY13536.1 - 7.8e-16 58.4 0.2 1.1e-15 58.0 0.2 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ORY13536.1 - 1.5e-11 43.4 0.1 0.033 14.7 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 ORY13536.1 - 2.8e-07 30.7 0.3 0.035 14.4 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) VWA_3_C PF18571.1 ORY13536.1 - 0.41 10.5 2.0 30 4.6 0.1 2.8 3 0 0 3 3 3 0 von Willebrand factor type A C-terminal domain ABM PF03992.16 ORY13538.1 - 2.4e-09 37.2 0.3 5.9e-05 23.1 0.1 2.5 2 0 0 2 2 2 2 Antibiotic biosynthesis monooxygenase NIPSNAP PF07978.13 ORY13538.1 - 0.0033 17.6 0.0 0.064 13.5 0.0 2.1 2 0 0 2 2 2 1 NIPSNAP SOR PF07682.11 ORY13538.1 - 0.011 14.6 1.0 9.6 5.0 0.0 2.9 1 1 2 3 3 3 0 Sulphur oxygenase reductase Phage_connect_1 PF05135.13 ORY13538.1 - 0.019 15.5 0.0 0.044 14.3 0.0 1.7 1 1 0 1 1 1 0 Phage gp6-like head-tail connector protein p450 PF00067.22 ORY13539.1 - 3.3e-55 187.7 0.0 4.1e-55 187.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SIR2_2 PF13289.6 ORY13539.1 - 0.045 13.9 0.0 2 8.5 0.0 2.5 2 1 0 2 2 2 0 SIR2-like domain Acetyltransf_7 PF13508.7 ORY13540.1 - 1.8e-08 34.7 0.0 2.8e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORY13540.1 - 8.5e-08 32.4 0.0 1.1e-07 32.0 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ORY13540.1 - 2e-06 27.8 0.0 2.9e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 ORY13540.1 - 0.00023 21.2 0.1 0.00035 20.6 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ORY13540.1 - 0.0023 17.9 0.1 0.0081 16.1 0.1 1.8 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_1 PF00583.25 ORY13541.1 - 4.2e-12 46.3 0.0 5.3e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ORY13541.1 - 1.6e-08 34.8 0.0 2.5e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ORY13541.1 - 4.4e-08 33.1 0.0 6.4e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 ORY13541.1 - 0.0002 21.5 0.0 0.00028 21.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF4960 PF16324.5 ORY13541.1 - 0.05 13.2 0.2 0.059 12.9 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4960) Acetyltransf_9 PF13527.7 ORY13541.1 - 0.13 12.3 0.0 0.24 11.5 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Q_salvage PF10343.9 ORY13542.1 - 1.8e-131 437.9 0.1 2.2e-131 437.6 0.1 1.1 1 0 0 1 1 1 1 Potential Queuosine, Q, salvage protein family MJ1316 PF04457.12 ORY13542.1 - 0.14 12.9 0.2 13 6.6 0.0 2.7 2 1 0 2 2 2 0 MJ1316 RNA cyclic group end recognition domain ThiF PF00899.21 ORY13543.1 - 1.3e-69 234.2 0.0 1.9e-69 233.7 0.0 1.2 1 0 0 1 1 1 1 ThiF family UAE_UbL PF14732.6 ORY13543.1 - 4.1e-21 75.4 0.2 9.8e-21 74.2 0.2 1.6 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.9 ORY13543.1 - 2.7e-09 37.3 2.2 0.00013 22.0 0.1 3.0 1 1 1 2 2 2 2 Ubiquitin-activating enzyme active site DUF4695 PF15766.5 ORY13543.1 - 0.24 11.6 3.1 5.6 7.2 0.1 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4695) adh_short_C2 PF13561.6 ORY13544.1 - 5.1e-43 147.3 0.0 8.3e-30 104.1 0.0 2.9 3 0 0 3 3 3 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY13544.1 - 1e-39 136.0 0.0 1.8e-19 70.0 0.1 3.1 3 0 0 3 3 3 3 short chain dehydrogenase KR PF08659.10 ORY13544.1 - 3.2e-08 33.7 1.6 4.7e-07 29.9 1.1 2.6 2 1 0 2 2 2 1 KR domain GRA6 PF05084.13 ORY13544.1 - 0.012 15.6 0.3 0.018 15.0 0.3 1.3 1 0 0 1 1 1 0 Granule antigen protein (GRA6) TALPID3 PF15324.6 ORY13544.1 - 0.098 10.3 4.6 0.11 10.2 4.6 1.1 1 0 0 1 1 1 0 Hedgehog signalling target DUF3530 PF12048.8 ORY13544.1 - 0.15 11.4 0.7 0.22 10.9 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) KAR9 PF08580.10 ORY13544.1 - 1.6 7.2 3.3 2 6.8 3.3 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Skp1_POZ PF03931.15 ORY13545.1 - 4.5e-07 30.0 0.0 7.5e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain DUF423 PF04241.15 ORY13546.1 - 7.3e-25 87.0 2.1 9.7e-25 86.6 2.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF423) DUF3605 PF12239.8 ORY13547.1 - 5.3e-50 169.7 0.0 6.5e-50 169.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) PRMT5_TIM PF17285.2 ORY13548.1 - 5.3e-72 242.1 0.0 6.9e-72 241.7 0.0 1.1 1 0 0 1 1 1 1 PRMT5 TIM barrel domain PRMT5 PF05185.16 ORY13548.1 - 1.3e-69 233.5 0.0 2.1e-69 232.8 0.0 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_C PF17286.2 ORY13548.1 - 1.2e-59 201.2 0.0 2.1e-59 200.4 0.0 1.4 1 0 0 1 1 1 1 PRMT5 oligomerisation domain Met_10 PF02475.16 ORY13548.1 - 0.19 11.4 0.0 0.31 10.8 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein HA2 PF04408.23 ORY13549.1 - 1.6e-18 67.0 0.1 3.6e-18 65.8 0.1 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 ORY13549.1 - 4.7e-10 39.8 0.0 1.3e-09 38.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 ORY13549.1 - 4e-06 26.7 0.2 7.5e-06 25.8 0.2 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 ORY13549.1 - 8.7e-06 26.0 0.3 2.5e-05 24.6 0.1 1.9 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.22 ORY13549.1 - 0.0033 17.1 0.1 0.0083 15.8 0.1 1.7 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_19 PF13245.6 ORY13549.1 - 0.0034 17.7 0.1 0.0083 16.5 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 ORY13549.1 - 0.011 16.3 0.0 0.017 15.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain Flavi_DEAD PF07652.14 ORY13549.1 - 0.011 15.7 0.1 0.024 14.6 0.1 1.6 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_30 PF13604.6 ORY13549.1 - 0.013 15.2 0.0 0.028 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 ORY13549.1 - 0.073 12.1 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_7 PF12775.7 ORY13549.1 - 0.13 11.7 0.0 0.33 10.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region Cu-oxidase_2 PF07731.14 ORY13561.1 - 8.7e-40 135.6 8.4 1.9e-37 128.0 0.3 2.9 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 ORY13561.1 - 2.3e-39 134.1 2.4 2.3e-39 134.1 2.4 3.0 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase PF00394.22 ORY13561.1 - 9.1e-36 123.4 0.1 3.6e-34 118.2 0.0 2.6 2 0 0 2 2 2 1 Multicopper oxidase MFS_1 PF07690.16 ORY13563.1 - 3.3e-24 85.5 69.8 3.9e-24 85.2 63.9 3.5 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY13563.1 - 1.5e-13 50.5 6.8 1.5e-13 50.5 6.8 3.2 2 1 2 4 4 4 2 Sugar (and other) transporter TRI12 PF06609.13 ORY13563.1 - 2.5e-07 29.5 13.1 4.1e-07 28.8 13.1 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) His_Phos_1 PF00300.22 ORY13564.1 - 1.8e-31 109.3 0.1 2.9e-31 108.7 0.1 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF3086 PF11285.8 ORY13564.1 - 0.046 12.8 0.0 0.077 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3086) CbiQ PF02361.16 ORY13565.1 - 0.023 14.3 1.5 0.028 14.1 1.5 1.1 1 0 0 1 1 1 0 Cobalt transport protein Zn_clus PF00172.18 ORY13566.1 - 0.0016 18.5 3.6 0.0016 18.5 3.6 5.2 4 1 1 5 5 5 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Herpes_LMP2 PF07415.11 ORY13566.1 - 3.9 6.2 4.1 16 4.1 0.0 2.1 2 0 0 2 2 2 0 Gammaherpesvirus latent membrane protein (LMP2) protein TauD PF02668.16 ORY13567.1 - 3.3e-59 200.9 1.5 4.3e-59 200.5 1.5 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family ATG_C PF09333.11 ORY13567.1 - 0.012 15.9 0.0 0.022 15.1 0.0 1.4 1 0 0 1 1 1 0 Autophagy-related protein C terminal domain MFS_1 PF07690.16 ORY13568.1 - 1.3e-24 86.8 11.2 1.7e-24 86.5 11.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2070 PF09843.9 ORY13568.1 - 0.013 13.9 0.4 0.017 13.5 0.4 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) adh_short_C2 PF13561.6 ORY13569.1 - 7e-52 176.3 0.0 8.4e-52 176.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY13569.1 - 3.7e-50 170.1 0.0 4.3e-50 169.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORY13569.1 - 2.2e-11 44.0 0.0 3.4e-11 43.4 0.0 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 ORY13569.1 - 0.0065 16.0 0.0 0.01 15.3 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Glyco_transf_5 PF08323.11 ORY13569.1 - 0.033 13.9 0.1 0.11 12.2 0.0 1.9 3 0 0 3 3 3 0 Starch synthase catalytic domain THF_DHG_CYH_C PF02882.19 ORY13569.1 - 0.079 12.3 0.1 0.19 11.1 0.0 1.6 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ADH_N PF08240.12 ORY13570.1 - 1.6e-28 98.7 0.2 2.8e-28 97.9 0.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORY13570.1 - 4.4e-13 49.3 0.0 7.7e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 ORY13570.1 - 1.1e-12 47.9 0.0 2.7e-05 23.8 0.0 2.4 2 1 0 2 2 2 2 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 ORY13570.1 - 0.021 15.9 0.0 0.052 14.6 0.0 1.6 2 0 0 2 2 2 0 Zinc-binding dehydrogenase tRNA-synt_1 PF00133.22 ORY13571.1 - 4.5e-34 117.7 0.0 3.8e-26 91.5 0.0 2.9 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 ORY13571.1 - 4.4e-14 52.1 0.2 7.5e-09 34.8 0.0 2.7 3 0 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 ORY13571.1 - 8.9e-13 48.5 0.0 2.6e-12 47.0 0.0 1.8 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 ORY13571.1 - 5.3e-11 42.4 0.1 1.5e-10 40.9 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 ORY13571.1 - 0.067 12.1 0.0 0.15 10.9 0.0 1.5 1 0 0 1 1 1 0 tRNA synthetases class I (K) LIM_bind PF01803.16 ORY13574.1 - 2.1e-58 197.7 0.6 2.1e-58 197.7 0.6 6.5 4 2 1 6 6 6 1 LIM-domain binding protein ATP-synt_ab PF00006.25 ORY13576.1 - 3.4e-67 226.2 0.0 4.7e-67 225.7 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 ORY13576.1 - 3e-14 53.3 0.6 6.2e-14 52.3 0.6 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain DUF5535 PF17687.1 ORY13576.1 - 0.02 15.0 0.1 0.053 13.7 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5535) DUF3533 PF12051.8 ORY13576.1 - 0.17 10.8 0.0 0.26 10.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) BTB PF00651.31 ORY13577.1 - 6.7e-07 29.5 0.1 1.3e-06 28.6 0.1 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 ORY13578.1 - 0.0073 16.5 0.0 0.009 16.2 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain ACP PF06857.11 ORY13578.1 - 0.041 14.1 0.1 0.055 13.7 0.1 1.2 1 0 0 1 1 1 0 Malonate decarboxylase delta subunit (MdcD) DUF4891 PF16232.5 ORY13578.1 - 0.14 12.7 0.0 0.16 12.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4891) FSH1 PF03959.13 ORY13580.1 - 5.8e-18 65.3 0.0 1.2e-17 64.3 0.0 1.4 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 ORY13580.1 - 5.8e-05 23.0 0.1 0.0002 21.2 0.1 1.7 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 ORY13580.1 - 0.00045 20.9 0.1 0.00055 20.6 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ORY13580.1 - 0.14 11.8 0.0 0.26 10.9 0.0 1.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold AMP-binding PF00501.28 ORY13581.1 - 7.6e-74 248.8 0.0 1.2e-73 248.1 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.26 ORY13581.1 - 2.5e-71 240.2 0.0 2.8e-69 233.5 0.0 3.1 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain Condensation PF00668.20 ORY13581.1 - 1.9e-57 195.0 0.1 3e-57 194.3 0.1 1.2 1 0 0 1 1 1 1 Condensation domain PS-DH PF14765.6 ORY13581.1 - 3e-50 171.2 0.0 5e-50 170.4 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 ORY13581.1 - 5.8e-49 166.4 0.1 2.1e-48 164.6 0.1 2.0 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.21 ORY13581.1 - 4.4e-44 151.3 0.0 7.8e-44 150.5 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 ORY13581.1 - 2.8e-28 98.3 0.0 2.2e-27 95.4 0.0 2.6 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.25 ORY13581.1 - 3.5e-18 65.7 0.5 5.9e-08 33.0 0.0 3.0 2 0 0 2 2 2 2 Phosphopantetheine attachment site adh_short PF00106.25 ORY13581.1 - 8e-12 45.0 0.1 2e-11 43.7 0.1 1.7 1 0 0 1 1 1 1 short chain dehydrogenase Methyltransf_23 PF13489.6 ORY13581.1 - 1.7e-11 44.2 0.0 4.6e-11 42.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 ORY13581.1 - 3.7e-11 43.5 0.0 1.1e-10 42.0 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_12 PF08242.12 ORY13581.1 - 2.5e-10 41.0 0.0 8e-10 39.4 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY13581.1 - 1.7e-08 35.0 0.0 4.7e-08 33.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY13581.1 - 3.1e-08 34.2 0.0 1.3e-07 32.2 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.23 ORY13581.1 - 1.6e-05 24.4 0.0 3.2e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_31 PF13847.6 ORY13581.1 - 0.00023 21.0 0.0 0.00086 19.1 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain adh_short_C2 PF13561.6 ORY13581.1 - 0.00057 19.5 0.1 0.0014 18.3 0.1 1.6 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Ubie_methyltran PF01209.18 ORY13581.1 - 0.021 14.2 0.0 0.046 13.1 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family bZIP_1 PF00170.21 ORY13582.1 - 3.9 7.6 13.1 0.39 10.8 7.5 2.1 2 0 0 2 2 2 0 bZIP transcription factor ADH_zinc_N PF00107.26 ORY13584.1 - 1.2e-11 44.7 0.0 3.4e-11 43.2 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ORY13584.1 - 0.0039 18.2 0.0 0.0075 17.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase p450 PF00067.22 ORY13585.1 - 1.4e-55 188.9 0.0 1.7e-55 188.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ATP-grasp_3 PF02655.14 ORY13586.1 - 1.5e-08 34.9 0.0 3.3e-08 33.7 0.0 1.5 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.6 ORY13586.1 - 0.0069 16.0 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_YheCD PF14398.6 ORY13586.1 - 0.065 12.5 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 YheC/D like ATP-grasp ABC_membrane PF00664.23 ORY13587.1 - 7.7e-51 173.3 27.4 1.8e-33 116.3 12.2 3.1 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.27 ORY13587.1 - 1.4e-47 161.7 0.0 1.4e-26 93.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 ORY13587.1 - 3.1e-08 33.4 0.1 0.026 13.9 0.0 3.6 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 ORY13587.1 - 3.8e-06 27.0 3.4 0.0035 17.4 0.1 3.1 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_16 PF13191.6 ORY13587.1 - 4.9e-06 27.0 0.4 0.00036 20.9 0.1 2.7 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 ORY13587.1 - 1.4e-05 25.0 0.2 0.03 14.2 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 ORY13587.1 - 0.00057 19.6 1.9 0.028 14.2 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain Dynamin_N PF00350.23 ORY13587.1 - 0.00059 19.9 3.6 0.34 11.0 0.2 2.4 2 0 0 2 2 2 2 Dynamin family AAA_7 PF12775.7 ORY13587.1 - 0.00075 19.1 0.2 0.14 11.7 0.1 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_21 PF13304.6 ORY13587.1 - 0.0024 17.8 1.6 1.4 8.7 0.2 3.3 3 1 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system FtsK_SpoIIIE PF01580.18 ORY13587.1 - 0.0028 17.1 0.3 0.051 12.9 0.1 2.2 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_23 PF13476.6 ORY13587.1 - 0.0039 17.7 1.6 0.077 13.5 0.1 2.4 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 ORY13587.1 - 0.0088 16.2 0.5 0.0088 16.2 0.5 2.1 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_10 PF12846.7 ORY13587.1 - 0.018 14.0 0.1 0.036 13.0 0.1 1.4 1 0 0 1 1 1 0 AAA-like domain AAA_30 PF13604.6 ORY13587.1 - 0.018 14.8 1.8 0.46 10.2 0.1 2.7 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.6 ORY13587.1 - 0.024 14.9 0.8 0.69 10.2 0.1 2.8 2 1 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 ORY13587.1 - 0.041 13.6 0.2 10 5.8 0.0 2.6 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_25 PF13481.6 ORY13587.1 - 0.043 13.4 0.7 2 8.0 0.2 2.7 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 ORY13587.1 - 0.062 12.6 0.9 4.9 6.4 0.1 2.4 2 0 0 2 2 2 0 Zeta toxin CcmD PF04995.14 ORY13587.1 - 0.083 13.0 0.4 0.53 10.4 0.4 2.5 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) IIGP PF05049.13 ORY13587.1 - 0.093 11.8 0.5 0.91 8.5 0.1 2.2 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) cobW PF02492.19 ORY13587.1 - 0.14 11.8 0.2 7.8 6.1 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_15 PF13175.6 ORY13587.1 - 0.17 11.5 0.1 3.3 7.3 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain TsaE PF02367.17 ORY13587.1 - 0.2 11.7 1.1 8.9 6.3 0.1 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DEAD PF00270.29 ORY13587.1 - 0.53 10.0 2.3 2.6 7.8 0.7 2.6 2 1 0 2 2 2 0 DEAD/DEAH box helicase Wzy_C PF04932.15 ORY13587.1 - 4.6 6.9 15.8 0.18 11.4 0.2 3.5 3 1 0 3 3 2 0 O-Antigen ligase Orthoreo_P10 PF07204.11 ORY13587.1 - 8.4 6.4 7.6 6.1 6.9 0.6 2.9 2 1 1 3 3 3 0 Orthoreovirus membrane fusion protein p10 TP53IP5 PF15331.6 ORY13588.1 - 0.12 12.6 0.1 0.16 12.1 0.1 1.3 1 1 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 Mid2 PF04478.12 ORY13590.1 - 0.019 14.8 0.1 0.031 14.1 0.1 1.3 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor DUF997 PF06196.12 ORY13590.1 - 0.068 13.2 0.1 0.6 10.2 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF997) HET PF06985.11 ORY13592.1 - 1.1e-34 119.9 6.7 1.7e-34 119.3 6.7 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Pyr_redox_2 PF07992.14 ORY13593.1 - 1.8e-10 40.6 0.0 2.1e-07 30.5 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ORY13593.1 - 0.0055 16.3 0.2 0.0097 15.5 0.2 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 ORY13593.1 - 0.0092 16.0 0.0 0.056 13.4 0.0 2.3 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 ORY13593.1 - 0.042 13.1 0.0 7.3 5.7 0.0 2.5 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 ORY13593.1 - 0.067 12.4 0.0 0.45 9.7 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain Lactamase_B PF00753.27 ORY13594.1 - 1.2e-19 71.1 1.3 1.8e-19 70.6 1.3 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 ORY13594.1 - 0.0008 19.0 0.1 0.0014 18.2 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain SNF2_N PF00176.23 ORY13595.1 - 9.3e-25 87.1 0.1 1.7e-23 83.0 0.0 2.4 2 1 0 2 2 2 1 SNF2 family N-terminal domain DNA_methylase PF00145.17 ORY13595.1 - 1.3e-08 34.6 0.0 9.2e-06 25.2 0.0 2.8 2 1 1 3 3 3 2 C-5 cytosine-specific DNA methylase Helicase_C PF00271.31 ORY13595.1 - 0.0038 17.6 0.0 0.0087 16.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_UBOX PF13445.6 ORY13595.1 - 3.5 7.7 15.2 0.04 13.9 0.5 3.4 3 0 0 3 3 3 0 RING-type zinc-finger Shugoshin_C PF07557.11 ORY13595.1 - 8.8 6.2 8.9 0.13 12.1 0.7 2.3 2 0 0 2 2 2 0 Shugoshin C terminus Sortilin-Vps10 PF15902.5 ORY13596.1 - 4e-07 29.2 1.6 4e-05 22.6 0.0 2.8 2 1 0 2 2 2 2 Sortilin, neurotensin receptor 3, PSII_BNR PF14870.6 ORY13596.1 - 2e-05 24.0 7.4 0.00079 18.8 0.4 3.7 1 1 3 4 4 4 2 Photosynthesis system II assembly factor YCF48 BNR PF02012.20 ORY13596.1 - 0.63 10.3 23.5 0.9 9.8 0.1 5.9 6 0 0 6 6 6 0 BNR/Asp-box repeat FAD_binding_4 PF01565.23 ORY13599.1 - 2.4e-10 40.3 0.0 6e-10 39.0 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain adh_short PF00106.25 ORY13600.1 - 9.9e-41 139.3 0.4 1.3e-40 139.0 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY13600.1 - 2.1e-32 112.6 0.1 2.7e-32 112.2 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 ORY13600.1 - 0.0006 19.3 0.0 0.0019 17.6 0.0 1.7 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 ORY13600.1 - 0.012 15.1 0.1 0.025 14.0 0.1 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family EccE PF11203.8 ORY13600.1 - 0.023 15.0 0.0 5.4 7.4 0.0 2.2 2 0 0 2 2 2 0 Putative type VII ESX secretion system translocon, EccE NmrA PF05368.13 ORY13600.1 - 0.043 13.4 0.4 0.069 12.7 0.0 1.5 2 0 0 2 2 2 0 NmrA-like family ATP-grasp_3 PF02655.14 ORY13601.1 - 1.5e-06 28.3 0.0 3e-06 27.4 0.0 1.5 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.6 ORY13601.1 - 0.029 14.0 0.0 0.04 13.5 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp domain Pertus-S4-tox PF09275.10 ORY13602.1 - 0.13 12.6 0.0 0.22 11.8 0.0 1.3 1 0 0 1 1 1 0 Pertussis toxin S4 subunit DUF2884 PF11101.8 ORY13605.1 - 0.008 15.7 1.3 2.3 7.7 0.1 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF2884) Ank_2 PF12796.7 ORY13606.1 - 2.5e-05 24.8 0.0 0.01 16.4 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 ORY13606.1 - 0.011 16.2 0.4 14 6.4 0.0 4.0 4 1 0 4 4 4 0 Ankyrin repeat Ank_3 PF13606.6 ORY13606.1 - 0.012 16.1 0.0 29 5.7 0.0 3.6 4 0 0 4 4 4 0 Ankyrin repeat Glyco_hydro_7 PF00840.20 ORY13610.1 - 5.1e-168 559.3 9.5 5.8e-168 559.1 9.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 MCM PF00493.23 ORY13611.1 - 0.08 12.0 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain PanZ PF12568.8 ORY13612.1 - 0.0063 16.2 0.0 0.01 15.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain, PanZ Isochorismatase PF00857.20 ORY13613.1 - 1.5e-17 64.3 0.0 2.4e-17 63.7 0.0 1.3 1 1 0 1 1 1 1 Isochorismatase family Glyco_hydro_35 PF01301.19 ORY13614.1 - 1.3e-85 287.8 0.3 2.2e-85 287.1 0.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 ORY13614.1 - 2.7e-57 192.3 7.1 1.2e-32 112.8 0.0 3.5 4 0 0 4 4 4 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.9 ORY13614.1 - 2.6e-54 183.8 3.1 5.2e-54 182.8 3.1 1.5 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.6 ORY13614.1 - 6e-25 86.6 0.0 1.4e-24 85.4 0.0 1.7 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 Cellulase PF00150.18 ORY13614.1 - 0.0006 19.3 0.0 0.001 18.6 0.0 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_42 PF02449.15 ORY13614.1 - 0.0069 15.8 0.1 0.027 13.8 0.1 1.9 1 1 0 1 1 1 1 Beta-galactosidase HemeBinding_Shp PF11545.8 ORY13614.1 - 0.14 12.2 0.0 0.34 10.9 0.0 1.6 1 0 0 1 1 1 0 Cell surface heme-binding protein Shp Glyco_trans_2_3 PF13632.6 ORY13615.1 - 3.5e-14 53.2 0.5 3.5e-14 53.2 0.5 3.0 3 1 0 3 3 3 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 ORY13615.1 - 3.6e-12 46.4 0.0 6.2e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 ORY13615.1 - 3.2e-11 43.6 0.0 4.8e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Cellulose_synt PF03552.14 ORY13615.1 - 2.2e-07 29.8 0.2 0.017 13.6 0.7 3.0 1 1 2 3 3 3 2 Cellulose synthase Glyco_transf_21 PF13506.6 ORY13615.1 - 5e-07 29.4 0.0 8.3e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Vma12 PF11712.8 ORY13615.1 - 0.22 11.6 0.0 0.48 10.5 0.0 1.5 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF1772 PF08592.11 ORY13615.1 - 0.5 10.7 5.8 0.41 10.9 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1772) Peptidase_M14 PF00246.24 ORY13616.1 - 4.4e-77 259.7 0.8 5.2e-77 259.5 0.8 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Shadoo PF14999.6 ORY13616.1 - 0.05 13.7 2.0 0.15 12.2 2.0 1.8 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective MFS_1 PF07690.16 ORY13617.1 - 6.8e-37 127.2 37.5 6.8e-37 127.2 37.5 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Endotoxin_mid PF09131.10 ORY13617.1 - 0.0007 19.3 0.6 1.1 8.8 0.1 2.3 2 0 0 2 2 2 2 Bacillus thuringiensis delta-Endotoxin, middle domain Arylsulfotran_2 PF14269.6 ORY13618.1 - 1.9e-38 132.6 0.3 6.2e-34 117.7 0.0 2.1 1 1 1 2 2 2 2 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 ORY13618.1 - 1.6e-06 27.3 0.1 4.4e-06 25.9 0.1 1.7 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) BTB PF00651.31 ORY13622.1 - 1e-09 38.6 0.0 3.9e-09 36.7 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain Sugar_tr PF00083.24 ORY13624.1 - 2.5e-81 273.8 16.5 2.9e-81 273.7 16.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY13624.1 - 3.8e-25 88.6 22.6 6.1e-22 78.0 13.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 ORY13624.1 - 3.2e-06 25.9 1.7 5.3e-06 25.1 1.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.6 ORY13624.1 - 6.7e-05 21.6 0.3 6.7e-05 21.6 0.3 2.8 2 1 0 3 3 3 1 MFS/sugar transport protein DUF4293 PF14126.6 ORY13624.1 - 0.0059 16.9 1.6 0.017 15.4 1.6 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4293) Gate PF07670.14 ORY13624.1 - 1.6 9.1 8.3 6.4 7.1 0.6 3.3 2 2 1 3 3 3 0 Nucleoside recognition adh_short PF00106.25 ORY13625.1 - 1.5e-09 37.6 0.0 8e-06 25.4 0.0 2.3 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 ORY13625.1 - 0.041 13.8 0.0 0.066 13.1 0.0 1.3 1 0 0 1 1 1 0 KR domain Trp_syntA PF00290.20 ORY13627.1 - 2.3e-90 302.0 0.0 4.4e-90 301.0 0.0 1.5 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.25 ORY13627.1 - 3.3e-48 164.6 1.1 6e-48 163.8 1.1 1.4 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Na_sulph_symp PF00939.19 ORY13627.1 - 4e-30 105.3 38.3 6.4e-30 104.6 38.3 1.2 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region SPX PF03105.19 ORY13627.1 - 1.1e-27 98.0 0.4 1.4e-27 97.6 0.4 1.1 1 0 0 1 1 1 1 SPX domain CitMHS PF03600.16 ORY13627.1 - 2.1e-27 96.1 60.1 9.7e-24 84.1 39.0 2.3 1 1 1 2 2 2 2 Citrate transporter RFX_DNA_binding PF02257.15 ORY13627.1 - 0.072 13.7 0.1 0.58 10.8 0.2 2.2 2 0 0 2 2 2 0 RFX DNA-binding domain VapB_antitoxin PF09957.9 ORY13627.1 - 0.086 12.8 0.1 21 5.1 0.0 2.5 2 0 0 2 2 2 0 Bacterial antitoxin of type II TA system, VapB zf-AD PF07776.15 ORY13631.1 - 0.061 13.6 0.7 0.54 10.5 0.0 2.3 2 0 0 2 2 2 0 Zinc-finger associated domain (zf-AD) MIOX PF05153.15 ORY13632.1 - 2.3e-119 397.6 0.2 2.7e-119 397.3 0.2 1.1 1 0 0 1 1 1 1 Myo-inositol oxygenase Aldo_ket_red PF00248.21 ORY13633.1 - 3.5e-43 147.9 0.0 2.3e-41 141.9 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Nucleoporin_FG PF13634.6 ORY13634.1 - 1.1e-14 55.0 36.9 1.8e-09 38.3 16.7 8.2 4 2 3 7 7 7 3 Nucleoporin FG repeat region SPX PF03105.19 ORY13635.1 - 0.64 9.9 5.3 0.92 9.4 5.3 1.2 1 0 0 1 1 1 0 SPX domain DUF743 PF05332.11 ORY13636.1 - 0.058 13.5 0.0 4.1 7.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF743) hnRNP_Q_AcD PF18360.1 ORY13636.1 - 0.14 12.2 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Heterogeneous nuclear ribonucleoprotein Q acidic domain HET PF06985.11 ORY13637.1 - 2.7e-28 99.2 0.9 5.6e-28 98.1 0.9 1.6 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) cobW PF02492.19 ORY13638.1 - 7.5e-33 113.6 0.0 9.3e-33 113.3 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 ORY13638.1 - 5.2e-06 25.6 0.2 0.0024 16.9 0.0 2.1 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 ORY13638.1 - 0.005 16.9 0.0 0.015 15.4 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_23 PF13476.6 ORY13638.1 - 0.013 16.0 0.1 0.017 15.6 0.1 1.2 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 ORY13638.1 - 0.12 12.2 0.0 0.27 11.1 0.0 1.6 2 0 0 2 2 2 0 NACHT domain AAA_5 PF07728.14 ORY13638.1 - 0.16 12.0 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 ORY13638.1 - 0.18 12.4 0.0 0.32 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain PRK PF00485.18 ORY13638.1 - 0.19 11.5 0.1 0.75 9.5 0.0 1.9 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Cytochrom_c3_2 PF14537.6 ORY13639.1 - 0.48 10.9 5.4 0.36 11.3 0.7 2.3 2 0 0 2 2 2 0 Cytochrome c3 zf-C2H2_4 PF13894.6 ORY13639.1 - 0.88 10.6 7.4 0.35 11.8 1.3 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.26 ORY13639.1 - 1.2 9.8 4.9 0.53 10.8 1.2 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type PAGK PF15284.6 ORY13640.1 - 0.12 12.3 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 Phage-encoded virulence factor Chorismate_bind PF00425.18 ORY13642.1 - 1e-90 303.8 0.0 5.7e-90 301.4 0.0 1.9 2 0 0 2 2 2 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 ORY13642.1 - 1.8e-29 102.7 0.0 1.6e-24 86.7 0.0 3.7 4 0 0 4 4 4 2 Anthranilate synthase component I, N terminal region FragX_IP PF05994.11 ORY13642.1 - 0.18 9.8 0.0 0.25 9.4 0.0 1.1 1 0 0 1 1 1 0 Cytoplasmic Fragile-X interacting family CFEM PF05730.11 ORY13644.1 - 2.5e-15 56.3 8.1 4.3e-15 55.6 8.1 1.4 1 0 0 1 1 1 1 CFEM domain zf-HIT PF04438.16 ORY13645.1 - 1.4e-11 44.1 10.7 1.8e-11 43.7 10.7 1.2 1 0 0 1 1 1 1 HIT zinc finger zf-MYND PF01753.18 ORY13645.1 - 0.0097 16.0 5.8 0.014 15.4 5.8 1.3 1 0 0 1 1 1 1 MYND finger zf-B_box PF00643.24 ORY13645.1 - 0.1 12.8 5.1 0.16 12.1 5.1 1.2 1 0 0 1 1 1 0 B-box zinc finger PRIMA1 PF16101.5 ORY13645.1 - 0.34 11.0 6.2 0.49 10.4 6.2 1.3 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 zf-C6H2 PF15801.5 ORY13645.1 - 0.36 11.2 7.7 0.76 10.1 7.7 1.4 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding zf-Mss51 PF13824.6 ORY13645.1 - 0.58 10.3 4.4 1.1 9.5 4.4 1.4 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 CAP_N PF01213.19 ORY13645.1 - 2.2 7.7 5.4 3 7.2 5.4 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal CtaG_Cox11 PF04442.14 ORY13646.1 - 5.4e-60 201.8 0.0 1.4e-59 200.4 0.0 1.6 2 0 0 2 2 2 1 Cytochrome c oxidase assembly protein CtaG/Cox11 DUF1772 PF08592.11 ORY13673.1 - 3e-07 30.8 4.0 5.1e-07 30.1 4.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) LIM_bind PF01803.16 ORY13673.1 - 0.19 11.2 0.0 0.29 10.6 0.0 1.2 1 0 0 1 1 1 0 LIM-domain binding protein EphA2_TM PF14575.6 ORY13674.1 - 0.094 13.6 0.0 0.19 12.6 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain z-alpha PF02295.17 ORY13676.1 - 0.087 12.9 0.7 19 5.4 0.0 2.7 3 0 0 3 3 3 0 Adenosine deaminase z-alpha domain CEL_III_C PF18054.1 ORY13677.1 - 1.3 9.1 4.8 0.95 9.5 2.8 1.7 2 0 0 2 2 2 0 CEL-III C-terminal Glyco_hydro_127 PF07944.12 ORY13678.1 - 1.1e-136 456.4 0.3 1.3e-136 456.2 0.3 1.0 1 0 0 1 1 1 1 Beta-L-arabinofuranosidase, GH127 Glyco_hydro_88 PF07470.13 ORY13678.1 - 0.0047 16.1 1.2 1.3 8.0 0.0 2.3 1 1 1 2 2 2 2 Glycosyl Hydrolase Family 88 DUF4986 PF16375.5 ORY13678.1 - 0.056 14.1 0.0 0.16 12.7 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function Sugar_tr PF00083.24 ORY13680.1 - 2.8e-38 132.0 28.2 4.5e-29 101.6 18.3 3.4 1 1 1 2 2 2 2 Sugar (and other) transporter p450 PF00067.22 ORY13681.1 - 3.6e-63 213.9 0.0 4.3e-63 213.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 STPPase_N PF16891.5 ORY13681.1 - 0.16 12.5 0.1 11 6.5 0.0 2.5 2 0 0 2 2 2 0 Serine-threonine protein phosphatase N-terminal domain FAA_hydrolase PF01557.18 ORY13682.1 - 2.3e-51 174.6 0.0 3.2e-51 174.1 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 ORY13682.1 - 4e-34 117.0 0.0 6.5e-34 116.3 0.0 1.3 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal HgmA PF04209.13 ORY13683.1 - 6.7e-205 680.7 0.1 7.8e-205 680.5 0.1 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase Leo1 PF04004.13 ORY13684.1 - 1.1e-39 135.9 0.1 2.2e-39 135.0 0.1 1.5 1 0 0 1 1 1 1 Leo1-like protein Mob1_phocein PF03637.17 ORY13685.1 - 2.6e-42 144.7 0.1 1.9e-41 141.9 0.1 1.9 1 1 0 1 1 1 1 Mob1/phocein family Arf PF00025.21 ORY13686.1 - 6.7e-80 266.6 0.2 7.6e-80 266.4 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 ORY13686.1 - 2.5e-14 53.5 0.0 3.6e-14 53.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 ORY13686.1 - 3.9e-14 52.5 0.0 4.8e-14 52.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 ORY13686.1 - 1.8e-13 50.4 1.3 1.5e-09 37.5 0.2 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 ORY13686.1 - 1e-12 47.9 0.0 1.1e-12 47.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 ORY13686.1 - 1.7e-10 40.6 0.0 2.1e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 ORY13686.1 - 5.1e-06 26.6 0.0 7.8e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 ORY13686.1 - 0.01 15.2 0.7 0.023 14.0 0.7 1.7 1 1 0 1 1 1 0 6-phosphofructo-2-kinase CorA PF01544.18 ORY13687.1 - 1.1e-08 34.8 3.4 1.2e-06 28.1 0.9 2.5 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein MAPEG PF01124.18 ORY13688.1 - 3.8e-14 52.7 0.5 4.8e-14 52.4 0.5 1.1 1 0 0 1 1 1 1 MAPEG family DUF2306 PF10067.9 ORY13688.1 - 0.021 15.0 0.2 0.038 14.2 0.2 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2306) DUF4139 PF13598.6 ORY13689.1 - 9.9e-33 113.6 0.0 3.3e-32 111.9 0.0 1.9 2 1 0 2 2 2 1 Domain of unknown function (DUF4139) DUF4140 PF13600.6 ORY13689.1 - 1.5e-23 83.1 3.0 1.5e-23 83.1 3.0 3.4 2 1 0 3 3 3 1 N-terminal domain of unknown function (DUF4140) Nucleoporin_FG PF13634.6 ORY13689.1 - 0.003 18.4 8.1 0.003 18.4 8.1 2.9 2 1 0 3 3 3 1 Nucleoporin FG repeat region LMBR1 PF04791.16 ORY13689.1 - 4.2 6.2 10.7 6 5.6 10.7 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Rad60-SLD_2 PF13881.6 ORY13693.1 - 1.9e-13 50.5 0.0 3.4e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 ORY13693.1 - 2e-05 25.1 0.0 3.7e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.23 ORY13693.1 - 0.00059 19.5 0.0 0.001 18.8 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family DUF92 PF01940.16 ORY13694.1 - 1.5e-81 273.3 7.5 2.1e-81 272.8 7.5 1.2 1 0 0 1 1 1 1 Integral membrane protein DUF92 UMP1 PF05348.11 ORY13694.1 - 1.9e-38 131.3 0.1 3.6e-38 130.4 0.1 1.5 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 MFS_1 PF07690.16 ORY13697.1 - 1.5e-24 86.6 69.0 2.2e-23 82.8 57.5 3.1 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 ORY13697.1 - 3.7e-10 38.9 10.6 8.3e-10 37.7 10.6 1.6 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) TraP PF07296.11 ORY13697.1 - 0.084 12.1 2.1 8.3 5.5 0.1 3.0 3 0 0 3 3 3 0 TraP protein DUF4690 PF15756.5 ORY13699.1 - 0.0002 21.9 0.4 0.0011 19.5 0.1 2.3 2 0 0 2 2 2 1 Small Novel Rich in Cartilage SH3_9 PF14604.6 ORY13699.1 - 0.00037 20.3 0.1 0.00092 19.0 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 ORY13699.1 - 0.00072 19.1 0.7 0.0016 18.0 0.7 1.5 1 0 0 1 1 1 1 SH3 domain CYYR1 PF10873.8 ORY13699.1 - 0.0018 18.8 0.8 0.006 17.0 0.3 2.1 2 0 0 2 2 2 1 Cysteine and tyrosine-rich protein 1 Podoplanin PF05808.11 ORY13699.1 - 0.0068 16.5 0.0 0.014 15.5 0.0 1.5 1 0 0 1 1 1 1 Podoplanin Syndecan PF01034.20 ORY13699.1 - 0.18 11.7 0.3 0.46 10.4 0.3 1.6 1 0 0 1 1 1 0 Syndecan domain DAP10 PF07213.11 ORY13699.1 - 0.74 9.8 4.4 0.33 10.9 0.9 2.2 2 0 0 2 2 2 0 DAP10 membrane protein zf-H2C2_2 PF13465.6 ORY13700.1 - 1.7e-05 25.0 53.2 0.00057 20.2 2.0 7.2 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2 PF00096.26 ORY13700.1 - 0.015 15.7 1.2 0.015 15.7 1.2 8.4 8 0 0 8 8 8 0 Zinc finger, C2H2 type WLM PF08325.10 ORY13701.1 - 0.0068 16.5 0.3 0.0068 16.5 0.3 1.6 2 0 0 2 2 2 1 WLM domain HET PF06985.11 ORY13702.1 - 1.6e-32 112.9 1.2 4.2e-29 101.8 0.0 2.2 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Aldo_ket_red PF00248.21 ORY13703.1 - 8e-51 173.0 0.0 1.4e-50 172.2 0.0 1.3 1 1 0 1 1 1 1 Aldo/keto reductase family TA0956 PF11513.8 ORY13703.1 - 0.039 14.2 0.0 0.079 13.2 0.0 1.5 1 0 0 1 1 1 0 Thermoplasma acidophilum protein TA0956 NUDIX PF00293.28 ORY13704.1 - 8.5e-11 42.0 0.0 2e-10 40.8 0.0 1.6 1 1 0 1 1 1 1 NUDIX domain GST_C_3 PF14497.6 ORY13705.1 - 2.3e-06 27.7 0.1 4.6e-06 26.7 0.1 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 ORY13705.1 - 4.6e-05 23.3 0.1 7.9e-05 22.6 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 ORY13705.1 - 0.00032 21.0 0.0 0.0011 19.4 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 ORY13705.1 - 0.00035 20.8 0.0 0.00071 19.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 ORY13705.1 - 0.00099 19.3 0.0 0.0016 18.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 ORY13705.1 - 0.0046 17.5 0.0 0.0068 17.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain FAD_binding_3 PF01494.19 ORY13706.1 - 2.2e-14 53.5 3.8 6.6e-13 48.6 3.8 2.7 1 1 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 ORY13706.1 - 4.9e-05 23.4 0.2 0.013 15.5 0.1 2.8 3 0 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 ORY13706.1 - 0.00068 19.8 0.4 0.0016 18.7 0.4 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SE PF08491.10 ORY13706.1 - 0.0015 17.6 0.0 0.022 13.8 0.0 2.1 2 0 0 2 2 2 1 Squalene epoxidase Amino_oxidase PF01593.24 ORY13706.1 - 0.0061 15.9 0.0 0.0095 15.3 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 ORY13706.1 - 0.0095 15.2 1.7 0.57 9.4 0.3 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 ORY13706.1 - 0.097 11.5 0.0 0.84 8.4 0.0 2.3 3 0 0 3 3 3 0 Tryptophan halogenase Lycopene_cycl PF05834.12 ORY13706.1 - 0.18 10.8 1.0 0.4 9.7 0.2 2.0 2 1 0 2 2 2 0 Lycopene cyclase protein Rossmann-like PF10727.9 ORY13706.1 - 0.31 10.9 6.2 1.8 8.4 1.2 2.3 1 1 1 2 2 2 0 Rossmann-like domain Methyltransf_31 PF13847.6 ORY13708.1 - 0.00024 20.9 0.0 0.00041 20.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 ORY13708.1 - 0.00095 19.2 0.0 0.0013 18.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY13708.1 - 0.001 19.7 0.0 0.0019 18.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY13708.1 - 0.0011 18.8 0.0 0.0035 17.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY13708.1 - 0.0057 17.4 0.0 0.012 16.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ORY13708.1 - 0.016 14.8 0.0 0.024 14.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.13 ORY13708.1 - 0.083 12.3 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 ORY13708.1 - 0.096 12.0 0.0 0.23 10.8 0.0 1.5 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Mod_r PF07200.13 ORY13710.1 - 4.9e-33 114.3 0.3 6.3e-33 113.9 0.3 1.1 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein TFIIA PF03153.13 ORY13710.1 - 0.28 11.2 8.7 0.34 10.9 8.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DEC-1_N PF04625.13 ORY13711.1 - 0.1 11.6 5.5 0.11 11.5 5.5 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Pkinase PF00069.25 ORY13712.1 - 6.6e-60 202.7 0.0 9.3e-59 198.9 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY13712.1 - 4.8e-26 91.6 0.2 4.5e-21 75.3 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 ORY13712.1 - 9.4e-06 24.8 0.1 1.3e-05 24.3 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 ORY13712.1 - 0.00048 20.1 0.1 0.042 13.8 0.2 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 ORY13712.1 - 0.00064 19.1 0.0 0.0014 18.0 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 ORY13712.1 - 0.0078 15.6 0.0 0.019 14.3 0.0 1.6 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 ORY13712.1 - 0.047 13.3 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 RIO1 family DNA_RNApol_7kD PF03604.13 ORY13713.1 - 7.3e-17 60.7 4.7 9.6e-17 60.4 4.7 1.2 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit DUF3268 PF11672.8 ORY13713.1 - 0.00091 19.6 0.5 0.0084 16.4 0.5 1.9 1 1 0 1 1 1 1 zinc-finger-containing domain GFA PF04828.14 ORY13713.1 - 0.011 16.1 0.4 2.9 8.3 0.0 2.0 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme zinc-ribbon_6 PF10005.9 ORY13713.1 - 0.012 16.3 0.2 0.017 15.8 0.2 1.3 1 0 0 1 1 1 0 zinc-ribbon domain DZR PF12773.7 ORY13713.1 - 0.015 15.3 0.3 0.02 14.9 0.3 1.3 1 0 0 1 1 1 0 Double zinc ribbon zf-ISL3 PF14690.6 ORY13713.1 - 0.016 15.8 1.6 0.025 15.2 0.3 1.9 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 HypA PF01155.19 ORY13713.1 - 0.026 14.5 0.2 0.03 14.3 0.2 1.1 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF35_N PF12172.8 ORY13713.1 - 0.028 14.3 1.7 0.37 10.7 0.3 2.2 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) MCM_OB PF17207.3 ORY13713.1 - 0.056 13.3 0.2 0.062 13.1 0.2 1.1 1 0 0 1 1 1 0 MCM OB domain DUF951 PF06107.11 ORY13713.1 - 0.07 13.1 1.2 0.73 9.8 0.4 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF951) zinc_ribbon_13 PF09855.9 ORY13713.1 - 0.078 13.2 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) Zn-ribbon_8 PF09723.10 ORY13713.1 - 0.084 13.0 2.5 0.3 11.2 2.5 1.8 1 1 0 1 1 1 0 Zinc ribbon domain TF_Zn_Ribbon PF08271.12 ORY13713.1 - 0.17 11.4 5.6 0.94 9.1 0.8 2.2 1 1 1 2 2 2 0 TFIIB zinc-binding FMO-like PF00743.19 ORY13714.1 - 1.9e-12 46.4 0.3 1e-10 40.7 0.2 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 ORY13714.1 - 5.2e-10 39.4 0.0 1.4e-09 38.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 ORY13714.1 - 2.7e-09 36.7 0.2 7.2e-08 32.0 0.0 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ORY13714.1 - 1.3e-05 24.6 0.2 0.00039 19.7 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 ORY13714.1 - 1.3e-05 24.6 0.0 0.00039 19.8 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ORY13714.1 - 0.029 14.4 0.0 8.7 6.3 0.0 3.4 3 0 0 3 3 3 0 FAD-NAD(P)-binding CBF PF03914.17 ORY13716.1 - 2e-55 187.4 0.2 2e-55 187.4 0.2 2.5 3 1 0 3 3 3 1 CBF/Mak21 family BUD22 PF09073.10 ORY13716.1 - 0.0015 17.9 20.7 0.0015 17.9 20.7 2.7 3 0 0 3 3 3 1 BUD22 DNA_alkylation PF08713.11 ORY13716.1 - 0.0046 16.7 0.7 0.95 9.1 0.3 2.6 2 0 0 2 2 2 2 DNA alkylation repair enzyme Cnd1 PF12717.7 ORY13716.1 - 0.012 15.7 0.3 0.038 14.0 0.3 1.9 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 Glycos_transf_3 PF00591.21 ORY13717.1 - 3.4e-62 210.3 0.0 4.6e-62 209.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 ORY13717.1 - 8e-10 38.4 0.0 1.9e-09 37.2 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain zf-C2H2 PF00096.26 ORY13719.1 - 2.5e-06 27.6 8.7 2.2e-05 24.7 1.5 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY13719.1 - 2.7e-05 24.4 2.4 2.7e-05 24.4 2.4 3.1 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.6 ORY13719.1 - 0.00042 20.2 1.2 0.00088 19.2 0.4 1.9 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_4 PF13894.6 ORY13719.1 - 0.00055 20.6 6.4 0.0076 17.0 0.8 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORY13719.1 - 0.014 15.7 0.7 0.027 14.8 0.7 1.5 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ORY13719.1 - 0.24 11.9 0.4 0.24 11.9 0.4 2.1 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 ORY13719.1 - 2.7 7.8 6.4 1.8 8.4 1.0 2.6 2 0 0 2 2 2 0 C2H2-type zinc-finger domain ATP_bind_1 PF03029.17 ORY13721.1 - 1.1e-63 215.2 0.0 5.5e-62 209.7 0.0 2.9 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 ORY13721.1 - 4.7e-05 23.0 0.0 0.025 14.1 0.0 3.1 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 ORY13721.1 - 6.4e-05 23.0 0.0 0.00066 19.8 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 ORY13721.1 - 0.00057 19.4 0.2 0.45 9.9 0.0 3.4 4 0 0 4 4 3 1 ADP-ribosylation factor family AAA_22 PF13401.6 ORY13721.1 - 0.0015 18.9 0.0 0.0046 17.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain Roc PF08477.13 ORY13721.1 - 0.0016 18.7 0.0 0.39 10.9 0.0 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase MeaB PF03308.16 ORY13721.1 - 0.0024 16.9 0.0 0.15 11.0 0.0 2.3 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB NACHT PF05729.12 ORY13721.1 - 0.0035 17.3 0.0 0.0069 16.3 0.0 1.4 1 0 0 1 1 1 1 NACHT domain FeoB_N PF02421.18 ORY13721.1 - 0.0042 16.6 0.0 0.095 12.2 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B SRPRB PF09439.10 ORY13721.1 - 0.0083 15.6 0.4 0.99 8.8 0.0 2.6 3 0 0 3 3 3 1 Signal recognition particle receptor beta subunit AAA_33 PF13671.6 ORY13721.1 - 0.0098 16.1 1.0 0.015 15.5 0.0 1.7 2 0 0 2 2 1 1 AAA domain cobW PF02492.19 ORY13721.1 - 0.01 15.4 0.0 1.8 8.1 0.0 2.4 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SRP54 PF00448.22 ORY13721.1 - 0.021 14.5 0.0 1.3 8.6 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain RsgA_GTPase PF03193.16 ORY13721.1 - 0.028 14.3 0.0 11 5.8 0.0 3.1 3 0 0 3 3 3 0 RsgA GTPase AAA_30 PF13604.6 ORY13721.1 - 0.029 14.1 0.0 0.048 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.20 ORY13721.1 - 0.029 13.5 0.0 0.61 9.2 0.0 2.3 2 0 0 2 2 2 0 G-protein alpha subunit NB-ARC PF00931.22 ORY13721.1 - 0.03 13.5 0.1 0.1 11.8 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain Ras PF00071.22 ORY13721.1 - 0.044 13.4 0.0 6.6 6.3 0.0 2.4 2 0 0 2 2 2 0 Ras family AAA_24 PF13479.6 ORY13721.1 - 0.05 13.3 0.0 0.11 12.2 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 ORY13721.1 - 0.051 13.9 0.1 0.17 12.2 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain RNA_helicase PF00910.22 ORY13721.1 - 0.06 13.7 0.0 0.3 11.5 0.0 2.1 2 0 0 2 2 2 0 RNA helicase Pox_A32 PF04665.12 ORY13721.1 - 0.085 12.3 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_18 PF13238.6 ORY13721.1 - 0.097 13.2 0.3 0.3 11.6 0.0 2.0 2 0 0 2 2 1 0 AAA domain MobB PF03205.14 ORY13721.1 - 0.1 12.5 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B PduV-EutP PF10662.9 ORY13721.1 - 0.11 12.3 0.1 1.6 8.5 0.0 2.6 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Viral_helicase1 PF01443.18 ORY13721.1 - 0.13 11.9 0.0 0.29 10.9 0.0 1.6 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DUF87 PF01935.17 ORY13721.1 - 0.17 12.0 0.0 0.52 10.4 0.0 1.8 2 0 0 2 2 2 0 Helicase HerA, central domain PRK PF00485.18 ORY13721.1 - 0.21 11.3 0.6 2.1 8.0 0.0 2.1 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Methyltransf_32 PF13679.6 ORY13721.1 - 0.21 11.6 0.0 0.53 10.3 0.1 1.6 2 0 0 2 2 1 0 Methyltransferase domain AAA_19 PF13245.6 ORY13721.1 - 0.33 11.3 1.2 0.74 10.1 0.0 2.1 2 1 0 2 2 2 0 AAA domain CwfJ_C_1 PF04677.15 ORY13722.1 - 2.8e-27 95.0 0.0 4.5e-27 94.3 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 ORY13722.1 - 4.3e-27 94.9 0.5 4.3e-27 94.9 0.5 2.3 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 2 CDP-OH_P_transf PF01066.21 ORY13723.1 - 2.4e-11 44.2 1.0 2.4e-11 44.2 1.0 2.1 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase CsbD PF05532.12 ORY13724.1 - 1.1e-07 31.6 5.5 7.3e-05 22.6 0.3 2.2 2 0 0 2 2 2 2 CsbD-like adh_short PF00106.25 ORY13725.1 - 2e-34 118.8 0.1 5.2e-23 81.5 0.0 2.3 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 ORY13725.1 - 1.7e-29 103.0 0.1 1.4e-13 51.0 0.0 2.5 1 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase WD40 PF00400.32 ORY13725.1 - 2.9e-22 78.5 1.0 0.00018 22.3 0.0 6.2 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY13725.1 - 2.4e-14 53.4 0.1 0.0041 17.4 0.0 6.0 1 1 5 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain KR PF08659.10 ORY13725.1 - 1.6e-11 44.4 0.3 5.5e-11 42.7 0.1 1.9 2 0 0 2 2 2 1 KR domain Cytochrom_D1 PF02239.16 ORY13725.1 - 0.00076 18.1 0.0 0.012 14.2 0.0 2.3 1 1 1 2 2 2 1 Cytochrome D1 heme domain WD40_like PF17005.5 ORY13725.1 - 0.0048 16.3 0.0 6.1 6.1 0.0 3.0 3 0 0 3 3 3 2 WD40-like domain Ge1_WD40 PF16529.5 ORY13725.1 - 0.011 14.7 0.0 0.71 8.8 0.0 2.7 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein HET PF06985.11 ORY13728.1 - 1.3e-23 84.0 0.1 2.6e-23 83.0 0.1 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Glyco_hydro_17 PF00332.18 ORY13729.1 - 1e-26 94.3 1.4 8.8e-26 91.2 1.4 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 Tubulin-binding PF00418.19 ORY13729.1 - 0.043 13.8 0.1 1.2 9.2 0.0 2.4 2 0 0 2 2 2 0 Tau and MAP protein, tubulin-binding repeat Glyco_hydro_47 PF01532.20 ORY13730.1 - 6.2e-166 552.8 0.2 7.2e-166 552.6 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF1543 PF07566.12 ORY13730.1 - 0.13 12.1 0.1 0.28 10.9 0.1 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1543) MFS_1 PF07690.16 ORY13731.1 - 1e-38 133.2 42.0 1e-38 133.2 42.0 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 ORY13731.1 - 7.1e-05 21.4 5.0 7.1e-05 21.4 5.0 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Herpes_US9 PF06072.11 ORY13731.1 - 0.12 12.3 0.2 0.79 9.6 0.2 2.5 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 RNA_pol_Rbc25 PF08292.12 ORY13731.1 - 0.13 12.5 0.8 0.22 11.8 0.8 1.3 1 0 0 1 1 1 0 RNA polymerase III subunit Rpc25 Aldedh PF00171.22 ORY13732.1 - 4.5e-107 358.4 0.1 5.4e-107 358.1 0.1 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family GN3L_Grn1 PF08701.11 ORY13733.1 - 8.6e-26 89.9 14.9 1.6e-25 89.0 14.9 1.5 1 0 0 1 1 1 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.23 ORY13733.1 - 9.5e-17 61.1 0.0 4.8e-13 49.2 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ORY13733.1 - 5.6e-06 26.4 0.0 3.6e-05 23.7 0.0 2.0 1 1 0 1 1 1 1 RsgA GTPase Dynamin_N PF00350.23 ORY13733.1 - 9.3e-06 25.8 3.9 0.18 11.8 0.0 3.7 3 1 1 4 4 4 2 Dynamin family FeoB_N PF02421.18 ORY13733.1 - 1.3e-05 24.7 0.1 6e-05 22.6 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_18 PF13238.6 ORY13733.1 - 0.0011 19.5 0.3 0.0036 17.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain GTP_EFTU PF00009.27 ORY13733.1 - 0.0015 18.1 0.0 0.25 10.8 0.0 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Arf PF00025.21 ORY13733.1 - 0.01 15.3 0.0 1.2 8.6 0.0 2.4 2 0 0 2 2 2 0 ADP-ribosylation factor family Roc PF08477.13 ORY13733.1 - 0.011 16.0 0.0 0.49 10.6 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 ORY13733.1 - 0.023 14.3 0.0 0.15 11.7 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 ORY13733.1 - 0.046 12.7 2.5 0.068 12.1 0.0 2.0 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB HET PF06985.11 ORY13734.1 - 4.9e-11 43.2 0.0 5.5e-11 43.0 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HAD_2 PF13419.6 ORY13735.1 - 8.4e-20 71.6 0.0 1.1e-19 71.2 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ORY13735.1 - 4.9e-06 27.0 0.0 0.028 14.7 0.0 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 ORY13735.1 - 0.00033 21.1 0.0 0.00069 20.1 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase ADH_zinc_N PF00107.26 ORY13735.1 - 0.028 14.4 0.3 0.056 13.4 0.1 1.5 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Hydrolase_like PF13242.6 ORY13735.1 - 0.052 13.6 0.0 0.17 12.0 0.0 1.8 2 0 0 2 2 2 0 HAD-hyrolase-like Hydrolase_6 PF13344.6 ORY13735.1 - 0.1 12.7 0.0 1.8 8.7 0.0 2.5 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 ORY13735.1 - 0.13 12.0 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Homeodomain PF00046.29 ORY13737.1 - 3.3e-13 49.3 0.2 7e-13 48.2 0.2 1.5 1 0 0 1 1 1 1 Homeodomain APS_kinase PF01583.20 ORY13738.1 - 1.9e-70 235.8 0.0 2.5e-70 235.4 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.6 ORY13738.1 - 1.1e-05 25.6 0.0 1.8e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 ORY13738.1 - 0.00027 21.5 0.0 0.00044 20.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 ORY13738.1 - 0.0012 18.3 0.0 0.0023 17.4 0.0 1.5 2 0 0 2 2 2 1 Chromatin associated protein KTI12 6PF2K PF01591.18 ORY13738.1 - 0.0016 17.8 0.0 0.027 13.8 0.0 2.1 2 0 0 2 2 2 1 6-phosphofructo-2-kinase G-alpha PF00503.20 ORY13738.1 - 0.02 14.0 0.0 0.026 13.7 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit AAA_29 PF13555.6 ORY13738.1 - 0.028 14.2 0.0 0.047 13.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 ORY13738.1 - 0.078 13.4 0.1 0.1 13.0 0.1 1.4 1 1 0 1 1 1 0 AAA ATPase domain Zeta_toxin PF06414.12 ORY13738.1 - 0.085 12.1 0.0 0.3 10.3 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin Thymidylate_kin PF02223.17 ORY13738.1 - 0.096 12.3 0.2 8.9 5.9 0.0 2.2 2 1 0 2 2 2 0 Thymidylate kinase DUF463 PF04317.12 ORY13738.1 - 0.14 11.0 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 YcjX-like family, DUF463 LCE6A PF15858.5 ORY13739.1 - 2.7 8.8 6.1 2.7 8.8 4.0 2.2 1 1 1 2 2 2 0 Late cornified envelope protein 6A family TMA7 PF09072.10 ORY13740.1 - 1.5e-18 67.4 17.1 1.6e-18 67.2 17.1 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 Amidohydro_2 PF04909.14 ORY13741.1 - 5.5e-23 82.2 0.0 8.1e-23 81.6 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase DNA_pol_viral_N PF00242.17 ORY13742.1 - 0.041 13.4 5.5 0.05 13.1 5.5 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain DUF4533 PF15047.6 ORY13742.1 - 0.37 10.3 1.0 0.49 9.9 0.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4533) DBR1 PF05011.13 ORY13743.1 - 9.4e-45 152.4 0.0 1.5e-44 151.8 0.0 1.3 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.28 ORY13743.1 - 6.7e-06 26.7 1.2 1.2e-05 26.0 1.2 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Rpr2 PF04032.16 ORY13744.1 - 2.5e-12 46.9 0.6 4.1e-12 46.2 0.1 1.6 2 0 0 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-HIT PF04438.16 ORY13744.1 - 1.1 9.2 4.6 11 6.0 0.4 2.2 2 0 0 2 2 2 0 HIT zinc finger PSCyt3 PF07627.11 ORY13744.1 - 7.4 6.9 6.6 7.5 6.9 0.3 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF1588) zf-ZPR1 PF03367.13 ORY13745.1 - 7.7e-116 383.3 1.0 2.1e-58 196.7 0.1 2.1 2 0 0 2 2 2 2 ZPR1 zinc-finger domain HypA PF01155.19 ORY13745.1 - 0.0067 16.4 2.4 2.8 8.0 0.3 2.6 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Haem_bd PF14376.6 ORY13745.1 - 0.19 11.7 0.5 1.1 9.3 0.6 2.1 1 1 0 1 1 1 0 Haem-binding domain Cytochrome_C7 PF14522.6 ORY13745.1 - 0.28 11.2 5.4 0.087 12.8 0.5 2.4 2 1 0 2 2 2 0 Cytochrome c7 and related cytochrome c zf-RRPl_C4 PF17026.5 ORY13745.1 - 0.28 11.3 3.4 5.5 7.2 0.6 2.4 2 0 0 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type zinc-ribbons_6 PF07191.12 ORY13745.1 - 2.7 8.0 6.3 3 7.9 0.9 2.4 2 1 0 2 2 2 0 zinc-ribbons DZR PF12773.7 ORY13745.1 - 3.9 7.6 9.8 30 4.8 3.3 3.6 3 1 0 3 3 3 0 Double zinc ribbon Pro_isomerase PF00160.21 ORY13746.1 - 5.3e-50 169.8 0.0 6.1e-50 169.6 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Arrestin_C PF02752.22 ORY13747.1 - 4.1e-13 49.9 0.0 1.3e-12 48.3 0.0 1.8 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Aldo_ket_red PF00248.21 ORY13749.1 - 8.1e-40 136.8 0.0 9.3e-40 136.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Phage_holin_3_7 PF05449.11 ORY13750.1 - 0.17 11.9 0.7 0.31 11.1 0.7 1.3 1 0 0 1 1 1 0 Putative 3TM holin, Phage_holin_3 DUF3417 PF11897.8 ORY13750.1 - 0.18 12.3 0.9 0.7 10.4 0.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3417) SUZ PF12752.7 ORY13752.1 - 0.00067 20.4 10.0 0.00067 20.4 10.0 3.8 4 2 0 4 4 4 1 SUZ domain FAM176 PF14851.6 ORY13752.1 - 0.34 10.5 2.9 12 5.5 0.1 2.2 2 0 0 2 2 2 0 FAM176 family eIF3_subunit PF08597.10 ORY13752.1 - 6.9 6.5 15.1 7.3 6.4 4.5 2.1 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit DUF1804 PF08822.11 ORY13753.1 - 0.63 10.0 2.3 0.85 9.6 2.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1804) CBFD_NFYB_HMF PF00808.23 ORY13754.1 - 1.4e-10 41.3 0.1 2.2e-10 40.7 0.1 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 ORY13754.1 - 1.3e-05 25.5 0.0 1.3e-05 25.5 0.0 2.4 2 1 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 ORY13754.1 - 0.00022 21.3 0.2 0.00033 20.8 0.2 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-X PF09415.10 ORY13754.1 - 0.018 15.3 0.0 0.018 15.3 0.0 2.3 2 1 0 2 2 2 0 CENP-S associating Centromere protein X TAFII28 PF04719.14 ORY13754.1 - 0.019 15.0 0.1 0.047 13.8 0.1 1.6 1 0 0 1 1 1 0 hTAFII28-like protein conserved region Bromo_TP PF07524.13 ORY13754.1 - 0.095 12.7 0.1 0.16 12.0 0.1 1.3 1 0 0 1 1 1 0 Bromodomain associated BUD22 PF09073.10 ORY13754.1 - 0.14 11.5 20.2 0.17 11.2 20.2 1.1 1 0 0 1 1 1 0 BUD22 TFIIA PF03153.13 ORY13754.1 - 0.8 9.6 19.7 1.1 9.2 19.7 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Hid1 PF12722.7 ORY13754.1 - 7.2 4.6 9.1 8.8 4.3 9.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Arrestin_N PF00339.29 ORY13755.1 - 0.0003 20.9 0.0 0.0013 18.8 0.0 2.0 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain DUF4930 PF16284.5 ORY13755.1 - 0.022 14.7 0.0 0.13 12.2 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4930) AhpC-TSA PF00578.21 ORY13755.1 - 0.19 11.7 0.0 0.39 10.6 0.0 1.5 1 0 0 1 1 1 0 AhpC/TSA family PAP1 PF08601.10 ORY13756.1 - 1.1 8.9 7.7 1.3 8.7 7.7 1.0 1 0 0 1 1 1 0 Transcription factor PAP1 Ion_trans PF00520.31 ORY13758.1 - 2.5e-130 433.0 86.1 6.5e-45 153.3 9.9 4.9 4 1 0 4 4 4 4 Ion transport protein GPHH PF16905.5 ORY13758.1 - 0.00054 19.7 0.0 0.0013 18.4 0.0 1.7 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated EF-hand_1 PF00036.32 ORY13758.1 - 0.0058 16.1 0.0 0.022 14.3 0.0 2.0 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 ORY13758.1 - 0.053 13.5 0.0 0.24 11.4 0.0 2.2 1 0 0 1 1 1 0 EF-hand domain EF-hand_7 PF13499.6 ORY13758.1 - 0.063 13.7 0.0 0.28 11.6 0.0 2.1 2 0 0 2 2 2 0 EF-hand domain pair PHD PF00628.29 ORY13759.1 - 9.3e-09 35.0 9.3 1.9e-08 34.0 9.3 1.6 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 ORY13759.1 - 0.014 14.9 5.8 0.035 13.7 5.8 1.6 1 0 0 1 1 1 0 PHD-finger DUF4486 PF14858.6 ORY13759.1 - 0.035 12.6 3.8 0.05 12.1 3.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4486) zf-UBR PF02207.20 ORY13759.1 - 0.46 10.7 5.0 1.1 9.5 5.0 1.5 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) EHN PF06441.12 ORY13760.1 - 3.2e-36 124.0 0.7 1e-34 119.1 0.0 2.2 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 ORY13760.1 - 1.5e-08 34.6 0.1 2.7e-08 33.8 0.1 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORY13760.1 - 0.0045 17.6 4.4 0.0045 17.6 4.4 2.1 2 1 0 2 2 2 1 Alpha/beta hydrolase family p450 PF00067.22 ORY13761.1 - 3.1e-53 181.2 0.0 4.5e-53 180.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 F-box PF00646.33 ORY13763.1 - 0.00013 21.8 0.3 0.00029 20.6 0.3 1.6 1 0 0 1 1 1 1 F-box domain F-box-like_2 PF13013.6 ORY13763.1 - 0.033 14.2 0.0 0.044 13.7 0.0 1.3 1 0 0 1 1 1 0 F-box-like domain Ank_5 PF13857.6 ORY13764.1 - 6.7e-41 137.8 9.3 1.8e-10 40.9 0.2 4.9 1 1 5 6 6 6 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 ORY13764.1 - 1.2e-33 115.5 1.9 2.6e-13 50.4 0.3 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY13764.1 - 1.3e-32 111.7 1.5 4.6e-09 36.6 0.0 5.9 2 1 4 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY13764.1 - 6e-31 103.0 1.5 7.7e-05 22.8 0.0 6.4 6 0 0 6 6 6 6 Ankyrin repeat Ank PF00023.30 ORY13764.1 - 9.9e-24 82.7 5.1 2.7e-06 27.6 0.0 6.2 6 0 0 6 6 6 6 Ankyrin repeat TMF_DNA_bd PF12329.8 ORY13765.1 - 4.9e-22 77.7 10.6 4.9e-22 77.7 10.6 4.9 4 1 0 4 4 4 1 TATA element modulatory factor 1 DNA binding ChAPs PF09295.10 ORY13765.1 - 0.043 12.8 0.1 0.063 12.3 0.1 1.2 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) Hairpins PF04877.12 ORY13765.1 - 0.13 11.9 1.8 0.24 11.0 1.8 1.4 1 0 0 1 1 1 0 HrpZ V_ATPase_I PF01496.19 ORY13765.1 - 0.86 7.4 13.5 0.45 8.4 11.6 1.4 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Mei5 PF10376.9 ORY13765.1 - 3.7 7.3 22.1 1.5 8.7 19.0 1.9 1 1 1 2 2 2 0 Double-strand recombination repair protein Prominin PF05478.11 ORY13765.1 - 5 4.9 8.9 6 4.7 8.3 1.3 1 1 0 1 1 1 0 Prominin Lectin_N PF03954.14 ORY13765.1 - 5.2 6.8 7.4 5.2 6.8 0.0 2.7 3 0 0 3 3 3 0 Hepatic lectin, N-terminal domain DUF1993 PF09351.10 ORY13765.1 - 7.5 6.7 14.8 1.7 8.8 0.7 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF1993) NPV_P10 PF05531.12 ORY13765.1 - 9.2 6.8 9.2 9 6.8 4.4 3.2 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein CN_hydrolase PF00795.22 ORY13766.1 - 2.6e-53 181.0 0.0 2.9e-53 180.9 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase p450 PF00067.22 ORY13768.1 - 6.5e-60 203.2 0.0 9.3e-53 179.6 0.0 2.1 1 1 0 2 2 2 2 Cytochrome P450 DRY_EERY PF09750.9 ORY13770.1 - 0.85 9.9 5.7 0.99 9.7 5.7 1.1 1 0 0 1 1 1 0 Alternative splicing regulator MFS_1 PF07690.16 ORY13771.1 - 1.5e-29 103.1 25.8 1.5e-29 103.1 25.8 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY13771.1 - 2.2e-14 53.2 2.2 2.2e-14 53.2 2.2 2.1 3 0 0 3 3 3 1 Sugar (and other) transporter Ceramidase PF05875.12 ORY13772.1 - 1.2e-79 267.4 0.1 1.5e-79 267.2 0.1 1.0 1 0 0 1 1 1 1 Ceramidase DUF3522 PF12036.8 ORY13772.1 - 0.00041 20.7 2.5 0.00089 19.6 2.5 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3522) Leader_Trp PF08255.11 ORY13772.1 - 0.048 13.6 1.8 0.16 12.0 1.8 1.9 1 0 0 1 1 1 0 Trp-operon Leader Peptide Aldo_ket_red PF00248.21 ORY13773.1 - 2.4e-61 207.5 0.0 2.8e-61 207.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Pkinase PF00069.25 ORY13790.1 - 1.7e-51 175.1 0.0 1.2e-50 172.3 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY13790.1 - 1.5e-20 73.6 0.0 2e-19 69.9 0.0 2.5 2 1 0 2 2 2 1 Protein tyrosine kinase Mis12 PF05859.12 ORY13791.1 - 2.3e-41 141.0 0.1 3.4e-41 140.5 0.1 1.3 1 0 0 1 1 1 1 Mis12 protein BCNT PF07572.12 ORY13792.1 - 6.3e-21 74.2 2.5 1.5e-20 73.1 2.5 1.6 1 0 0 1 1 1 1 Bucentaur or craniofacial development CDC45 PF02724.14 ORY13792.1 - 3.1 6.0 8.4 6 5.0 8.4 1.4 1 0 0 1 1 1 0 CDC45-like protein Ank_5 PF13857.6 ORY13793.1 - 0.0037 17.5 0.1 0.0097 16.2 0.1 1.6 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 ORY13793.1 - 0.062 13.9 0.0 1.1 9.9 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank PF00023.30 ORY13793.1 - 0.084 13.4 0.3 0.4 11.2 0.1 2.2 2 0 0 2 2 2 0 Ankyrin repeat MIF PF01187.18 ORY13794.1 - 0.00011 22.4 0.0 0.0086 16.4 0.0 2.4 1 1 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) CENP-X PF09415.10 ORY13796.1 - 3.4e-20 72.1 0.0 6.4e-20 71.3 0.0 1.5 1 0 0 1 1 1 1 CENP-S associating Centromere protein X Copper-bind PF00127.20 ORY13797.1 - 0.00017 22.0 0.1 0.00034 21.0 0.1 1.5 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Cu_bind_like PF02298.17 ORY13797.1 - 0.0038 17.2 0.9 0.046 13.7 0.9 2.1 1 1 0 1 1 1 1 Plastocyanin-like domain Cu-oxidase_3 PF07732.15 ORY13797.1 - 0.056 13.5 0.2 0.13 12.3 0.2 1.5 1 0 0 1 1 1 0 Multicopper oxidase Phage-tail_3 PF13550.6 ORY13797.1 - 0.11 12.3 0.2 0.11 12.3 0.2 1.6 2 0 0 2 2 2 0 Putative phage tail protein Thaumatin PF00314.17 ORY13798.1 - 3.9e-69 232.5 2.1 5.3e-69 232.1 2.1 1.2 1 0 0 1 1 1 1 Thaumatin family Glyco_hydro_64 PF16483.5 ORY13798.1 - 0.023 14.0 0.0 0.41 9.9 0.0 2.1 2 0 0 2 2 2 0 Beta-1,3-glucanase Mannosidase_ig PF17786.1 ORY13800.1 - 1.7e-19 70.2 0.6 5.1e-19 68.7 0.6 1.9 1 0 0 1 1 1 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 ORY13800.1 - 1.2e-10 42.0 0.6 1e-09 39.1 0.0 2.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.18 ORY13800.1 - 0.027 14.4 0.0 0.062 13.2 0.0 1.6 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, sugar binding domain Fungal_trans PF04082.18 ORY13801.1 - 1.6e-22 79.9 0.2 2.7e-22 79.1 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY13801.1 - 1.1e-07 31.8 8.5 2e-07 31.0 8.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Astacin PF01400.24 ORY13802.1 - 4.9e-14 52.4 0.5 7.1e-09 35.5 0.1 2.2 2 0 0 2 2 2 2 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.24 ORY13802.1 - 0.00093 19.1 0.5 0.002 18.0 0.2 1.7 1 1 1 2 2 2 1 Matrixin Reprolysin_4 PF13583.6 ORY13802.1 - 0.003 17.2 1.5 0.0033 17.1 0.1 1.7 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 ORY13802.1 - 0.0086 16.6 0.3 0.046 14.2 0.1 2.0 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 ORY13802.1 - 0.011 15.9 0.0 0.019 15.1 0.0 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12 DUF4953 PF16313.5 ORY13802.1 - 0.041 13.1 1.1 0.081 12.1 1.1 1.4 1 0 0 1 1 1 0 Met-zincin Cyt-b5 PF00173.28 ORY13804.1 - 1e-16 60.8 1.0 2.5e-16 59.6 0.1 2.0 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.13 ORY13804.1 - 4.3e-12 46.5 19.8 6.1e-12 46.0 19.1 1.6 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Anth_synt_I_N PF04715.13 ORY13804.1 - 0.13 12.5 0.1 0.24 11.6 0.1 1.4 1 0 0 1 1 1 0 Anthranilate synthase component I, N terminal region RRM_1 PF00076.22 ORY13805.1 - 1.8e-45 152.6 0.2 1.6e-23 82.3 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 ORY13805.1 - 3.8e-15 56.7 0.0 1.2e-14 55.1 0.0 2.0 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_occluded PF16842.5 ORY13805.1 - 4.6e-06 26.4 0.0 0.0039 17.0 0.0 3.3 3 0 0 3 3 3 1 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 ORY13805.1 - 5.1e-06 26.4 0.1 0.59 10.2 0.0 3.4 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 ORY13805.1 - 0.00092 18.8 0.0 0.22 11.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 ORY13805.1 - 0.0013 18.8 0.1 0.5 10.4 0.0 3.3 3 0 0 3 3 3 1 RNA binding motif PHM7_cyt PF14703.6 ORY13805.1 - 0.006 16.8 0.2 0.085 13.1 0.2 2.9 2 1 0 2 2 2 1 Cytosolic domain of 10TM putative phosphate transporter DUF2884 PF11101.8 ORY13805.1 - 0.031 13.8 0.0 0.08 12.4 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2884) RRM_7 PF16367.5 ORY13805.1 - 0.038 14.1 0.0 1.2 9.3 0.0 2.6 2 0 0 2 2 2 0 RNA recognition motif RRM_8 PF11835.8 ORY13805.1 - 0.042 14.1 0.0 0.3 11.3 0.0 2.3 2 0 0 2 2 2 0 RRM-like domain RisS_PPD PF16524.5 ORY13805.1 - 0.061 13.6 0.2 0.26 11.5 0.0 2.1 2 0 0 2 2 2 0 Periplasmic domain of Sensor histidine kinase RisS Spore_SspJ PF09575.10 ORY13805.1 - 0.41 11.1 1.5 40 4.7 0.0 2.7 2 0 0 2 2 2 0 Small spore protein J (Spore_SspJ) Ribosomal_L29 PF00831.23 ORY13806.1 - 9.8 6.2 7.6 15 5.6 0.6 3.4 3 0 0 3 3 3 0 Ribosomal L29 protein PP2C PF00481.21 ORY13807.1 - 1e-34 120.3 0.0 7.2e-29 101.2 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 ORY13807.1 - 0.00056 19.6 0.0 0.001 18.8 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C HEAT_EZ PF13513.6 ORY13808.1 - 1.2e-14 54.4 3.3 3.3e-07 30.7 0.0 8.3 9 0 0 9 9 9 2 HEAT-like repeat HEAT PF02985.22 ORY13808.1 - 3.5e-14 51.7 11.7 0.00069 19.7 0.1 9.9 11 0 0 11 11 9 2 HEAT repeat HEAT_2 PF13646.6 ORY13808.1 - 9.7e-08 32.3 10.2 0.016 15.6 0.1 7.0 4 2 4 8 8 8 4 HEAT repeats CLASP_N PF12348.8 ORY13808.1 - 1.2e-07 31.5 0.1 0.07 12.7 0.0 4.9 4 2 1 6 6 6 2 CLASP N terminal IBN_N PF03810.19 ORY13808.1 - 5.8e-07 29.3 1.8 0.00029 20.7 0.1 4.0 3 0 0 3 3 3 1 Importin-beta N-terminal domain Arm PF00514.23 ORY13808.1 - 2.2e-05 24.3 2.1 1.9 8.6 0.0 5.2 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat MMS19_N PF14500.6 ORY13808.1 - 0.00028 20.6 1.0 0.8 9.2 0.4 3.5 4 1 0 4 4 4 2 Dos2-interacting transcription regulator of RNA-Pol-II Ecm29 PF13001.7 ORY13808.1 - 0.00076 18.3 0.0 0.67 8.6 0.0 3.3 2 1 0 3 3 3 2 Proteasome stabiliser HEAT_PBS PF03130.16 ORY13808.1 - 0.0011 19.4 0.2 1.1e+02 4.0 0.0 6.2 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat DUF3385 PF11865.8 ORY13808.1 - 0.0034 17.3 0.7 1.2 9.1 0.8 3.5 2 1 1 3 3 3 1 Domain of unknown function (DUF3385) Uso1_p115_head PF04869.14 ORY13808.1 - 0.012 14.8 1.0 0.3 10.2 0.4 2.3 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, head region NUC173 PF08161.12 ORY13808.1 - 0.066 12.9 0.2 32 4.1 0.0 4.2 4 1 2 6 6 6 0 NUC173 domain RGS PF00615.19 ORY13808.1 - 0.17 12.2 0.2 0.93 9.8 0.0 2.4 2 0 0 2 2 2 0 Regulator of G protein signaling domain EF-hand_1 PF00036.32 ORY13809.1 - 5.3e-27 91.3 12.1 3.7e-07 29.2 0.6 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 ORY13809.1 - 7.4e-23 80.8 14.6 1.8e-13 50.7 1.6 2.9 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 ORY13809.1 - 3.1e-20 70.3 6.7 6.9e-05 22.5 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 ORY13809.1 - 1.8e-18 65.1 10.2 1.5e-06 27.4 0.3 4.3 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 ORY13809.1 - 1.5e-13 50.3 11.9 9.9e-05 22.1 0.5 4.0 2 1 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 ORY13809.1 - 1.2e-06 28.8 0.0 0.0029 17.9 0.0 2.3 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 ORY13809.1 - 3.1e-05 23.9 7.5 0.012 15.6 0.4 3.8 1 1 3 4 4 4 2 Cytoskeletal-regulatory complex EF hand Anillin PF08174.11 ORY13809.1 - 0.052 14.0 0.0 1.9 8.9 0.0 2.2 1 1 1 2 2 2 0 Cell division protein anillin EF-hand_9 PF14658.6 ORY13809.1 - 0.079 13.3 0.1 4 7.8 0.1 3.0 2 1 1 3 3 3 0 EF-hand domain Dockerin_1 PF00404.18 ORY13809.1 - 0.089 13.0 0.8 0.62 10.3 0.7 2.4 1 1 0 1 1 1 0 Dockerin type I domain PMBR PF09373.10 ORY13809.1 - 0.16 12.2 0.0 4.9 7.5 0.0 2.4 2 0 0 2 2 2 0 Pseudomurein-binding repeat DUF1770 PF08589.10 ORY13810.1 - 2.1e-32 112.0 1.7 2.8e-32 111.6 1.7 1.2 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1770) HD PF01966.22 ORY13812.1 - 0.014 15.6 0.0 0.021 15.1 0.0 1.3 1 0 0 1 1 1 0 HD domain Sugar_tr PF00083.24 ORY13813.1 - 0.043 12.7 16.1 0.39 9.5 16.2 2.1 1 1 0 1 1 1 0 Sugar (and other) transporter DUF3285 PF11688.8 ORY13813.1 - 0.11 12.4 2.3 7.7 6.5 0.6 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3285) Ferritin_2 PF13668.6 ORY13814.1 - 3e-06 27.5 0.0 5.2e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Ferritin-like domain MtN3_slv PF03083.16 ORY13815.1 - 0.44 10.6 2.4 2.2 8.4 0.4 2.3 1 1 1 2 2 2 0 Sugar efflux transporter for intercellular exchange NACHT PF05729.12 ORY13816.1 - 4.4e-08 33.2 3.8 2.3e-07 30.9 0.3 2.7 2 1 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 ORY13816.1 - 0.00012 22.5 0.1 0.001 19.5 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 ORY13816.1 - 0.00016 22.0 0.1 0.0018 18.6 0.0 2.7 2 1 0 2 2 2 1 AAA domain SesA PF17107.5 ORY13816.1 - 0.00046 20.4 5.0 0.00058 20.0 1.9 2.4 2 0 0 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases AAA_18 PF13238.6 ORY13816.1 - 0.007 16.9 0.1 0.037 14.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 ORY13816.1 - 0.0095 16.3 0.0 0.028 14.8 0.0 1.8 1 0 0 1 1 1 1 RNA helicase AAA_29 PF13555.6 ORY13816.1 - 0.012 15.3 0.3 0.064 13.0 0.3 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_33 PF13671.6 ORY13816.1 - 0.032 14.4 0.6 0.27 11.4 0.0 2.9 2 2 1 3 3 3 0 AAA domain Pol_alpha_B_N PF08418.10 ORY13816.1 - 0.05 13.6 0.6 0.093 12.7 0.6 1.5 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal MMR_HSR1 PF01926.23 ORY13816.1 - 0.058 13.5 0.3 0.27 11.3 0.0 2.2 2 1 1 3 3 2 0 50S ribosome-binding GTPase AAA PF00004.29 ORY13816.1 - 0.08 13.4 0.1 0.85 10.1 0.0 2.9 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 ORY13816.1 - 0.085 13.3 9.9 3.8 7.9 0.1 3.3 3 0 0 3 3 3 0 AAA domain RVT_3 PF13456.6 ORY13816.1 - 0.091 12.6 0.0 0.22 11.3 0.0 1.7 1 0 0 1 1 1 0 Reverse transcriptase-like ABC_tran PF00005.27 ORY13816.1 - 0.25 11.8 0.1 0.25 11.8 0.1 2.5 2 1 0 2 2 2 0 ABC transporter OmpH PF03938.14 ORY13816.1 - 0.38 11.1 4.6 6.6 7.1 3.3 2.6 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF3455 PF11937.8 ORY13817.1 - 4.9e-41 140.7 1.1 6e-41 140.5 1.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) PIGA PF08288.12 ORY13818.1 - 4.9e-47 158.5 4.5 6e-47 158.2 2.1 2.3 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glyco_transf_4 PF13439.6 ORY13818.1 - 3e-28 98.9 0.5 5.1e-28 98.2 0.5 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 ORY13818.1 - 2e-26 92.6 0.0 3.1e-26 91.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 ORY13818.1 - 8.6e-24 84.5 0.1 1.7e-23 83.5 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 ORY13818.1 - 4.5e-12 46.7 0.0 8.5e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.6 ORY13818.1 - 2e-05 24.6 0.1 4.3e-05 23.6 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.6 ORY13818.1 - 0.0053 17.1 0.0 0.034 14.5 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 ORY13818.1 - 0.083 12.6 0.0 0.19 11.4 0.0 1.8 1 1 0 1 1 1 0 Starch synthase catalytic domain Glyco_hydro_18 PF00704.28 ORY13819.1 - 4.7e-70 236.8 1.4 7e-70 236.2 1.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 ORY13819.1 - 2.7e-08 34.2 15.8 2.7e-08 34.2 15.8 4.6 5 0 0 5 5 5 2 Chitin recognition protein Chitin_bind_1 PF00187.19 ORY13820.1 - 2.5e-13 50.3 89.2 7.9e-06 26.2 20.9 5.3 5 0 0 5 5 5 3 Chitin recognition protein LysM PF01476.20 ORY13820.1 - 4.1e-06 26.7 1.2 0.022 14.8 0.0 2.8 3 0 0 3 3 3 2 LysM domain DEAD PF00270.29 ORY13822.1 - 8.7e-34 116.8 0.0 9.5e-31 106.9 0.0 2.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY13822.1 - 1.8e-20 73.3 0.0 5.8e-20 71.7 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY13822.1 - 2.4e-05 24.4 0.0 5.5e-05 23.2 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Asp PF00026.23 ORY13823.1 - 7.2e-65 219.5 10.4 8.5e-65 219.2 10.4 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.6 ORY13823.1 - 1.1e-06 29.2 1.6 0.0043 17.7 0.3 2.8 2 1 0 2 2 2 2 Aspartyl protease TAXi_N PF14543.6 ORY13823.1 - 0.00034 20.9 5.5 0.022 15.0 1.2 3.2 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Vps39_2 PF10367.9 ORY13824.1 - 3.2e-06 27.6 0.0 1.2e-05 25.7 0.0 1.9 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 Clathrin PF00637.20 ORY13824.1 - 9.8e-05 22.2 0.0 0.0026 17.7 0.0 2.5 2 0 0 2 2 2 1 Region in Clathrin and VPS CASP_C PF08172.12 ORY13825.1 - 2.4e-95 318.7 0.1 2.4e-95 318.7 0.1 3.7 3 1 1 4 4 4 2 CASP C terminal Fez1 PF06818.15 ORY13825.1 - 0.018 15.5 50.8 0.7 10.3 17.6 4.4 4 1 1 5 5 5 0 Fez1 ZapB PF06005.12 ORY13825.1 - 0.019 15.4 0.0 0.019 15.4 0.0 7.2 4 3 1 5 5 5 0 Cell division protein ZapB Surface_antigen PF11054.8 ORY13825.1 - 0.051 13.2 0.3 0.1 12.3 0.3 1.4 1 0 0 1 1 1 0 Sporozoite TA4 surface antigen APG6_N PF17675.1 ORY13825.1 - 0.11 13.0 65.7 4.9 7.7 12.2 5.7 2 1 3 5 5 5 0 Apg6 coiled-coil region V_ATPase_I PF01496.19 ORY13825.1 - 1.8 6.3 32.3 0.42 8.5 1.2 4.0 1 1 1 3 3 3 0 V-type ATPase 116kDa subunit family FlaC_arch PF05377.11 ORY13825.1 - 4.7 7.7 39.3 3.1 8.3 0.1 6.6 6 0 0 6 6 6 0 Flagella accessory protein C (FlaC) T3SS_needle_F PF09392.10 ORY13825.1 - 5.7 7.2 12.2 0.92 9.7 0.5 4.4 4 1 0 4 4 4 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF Shugoshin_N PF07558.11 ORY13825.1 - 7.6 6.5 14.2 0.1 12.5 1.0 3.7 4 0 0 4 4 4 0 Shugoshin N-terminal coiled-coil region Prefoldin_2 PF01920.20 ORY13826.1 - 3.3e-24 84.9 10.1 4.5e-24 84.4 10.1 1.2 1 0 0 1 1 1 1 Prefoldin subunit Gp58 PF07902.11 ORY13826.1 - 0.037 12.3 0.7 0.11 10.8 0.0 1.7 2 0 0 2 2 2 0 gp58-like protein NPV_P10 PF05531.12 ORY13826.1 - 0.055 13.9 2.8 0.92 10.0 0.1 2.1 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Spc24 PF08286.11 ORY13826.1 - 0.072 13.3 9.2 1.5 9.1 4.5 2.3 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 FlaC_arch PF05377.11 ORY13826.1 - 0.1 13.0 0.5 0.1 13.0 0.5 2.8 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF3338 PF11819.8 ORY13826.1 - 0.15 12.1 7.3 6.4 6.8 4.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3338) DUF4164 PF13747.6 ORY13826.1 - 0.2 12.0 10.3 0.57 10.5 5.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) APG6_N PF17675.1 ORY13826.1 - 0.23 12.0 16.6 0.41 11.2 10.8 2.2 2 0 0 2 2 2 0 Apg6 coiled-coil region AATF-Che1 PF13339.6 ORY13826.1 - 0.32 11.7 0.1 0.32 11.7 0.1 2.2 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor CENP-H PF05837.12 ORY13826.1 - 0.37 11.2 8.7 11 6.5 6.3 2.1 2 0 0 2 2 2 0 Centromere protein H (CENP-H) GAS PF13851.6 ORY13826.1 - 0.41 10.0 14.0 6.5 6.1 0.1 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DivIC PF04977.15 ORY13826.1 - 1.5 8.7 11.2 4.6 7.1 7.0 2.2 2 0 0 2 2 2 0 Septum formation initiator LMBR1 PF04791.16 ORY13826.1 - 1.6 7.5 3.7 1.9 7.3 3.7 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF1947 PF09183.10 ORY13826.1 - 3.5 8.0 9.3 0.84 10.0 3.4 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF1947) 5_nucleotid PF05761.14 ORY13826.1 - 6.7 5.5 7.6 14 4.4 7.6 1.5 1 1 0 1 1 1 0 5' nucleotidase family MFS_1 PF07690.16 ORY13827.1 - 1.5e-34 119.5 39.2 1.5e-34 119.5 39.2 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY13827.1 - 1.7e-14 53.6 1.4 1.7e-14 53.6 1.4 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter AA_permease_2 PF13520.6 ORY13828.1 - 6.9e-65 219.5 51.4 8.4e-65 219.2 51.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ORY13828.1 - 2e-10 39.9 42.3 3.4e-10 39.1 42.3 1.3 1 1 0 1 1 1 1 Amino acid permease Helo_like_N PF17111.5 ORY13829.1 - 1.1e-13 51.1 1.0 1.1e-13 51.1 1.0 2.6 1 1 0 2 2 2 1 Fungal N-terminal domain of STAND proteins Ank_4 PF13637.6 ORY13829.1 - 1.4e-12 47.9 1.2 0.0063 17.1 0.1 5.0 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 ORY13829.1 - 3e-09 36.9 0.1 0.0061 16.8 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY13829.1 - 2e-08 33.8 0.7 2.9e-05 24.1 0.0 4.4 4 0 0 4 4 4 1 Ankyrin repeat Ank PF00023.30 ORY13829.1 - 2.2e-08 34.2 1.5 0.00061 20.1 0.0 4.8 4 0 0 4 4 4 1 Ankyrin repeat Ank_2 PF12796.7 ORY13829.1 - 6.6e-08 33.0 0.1 6.6e-05 23.4 0.0 3.7 4 1 0 4 4 4 1 Ankyrin repeats (3 copies) SesA PF17107.5 ORY13829.1 - 0.0039 17.4 1.9 0.0051 17.0 0.3 2.1 2 0 0 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases AIF-MLS PF14962.6 ORY13829.1 - 0.021 14.8 2.0 0.034 14.1 2.0 1.2 1 0 0 1 1 1 0 Mitochondria Localisation Sequence Med9 PF07544.13 ORY13829.1 - 0.055 13.6 1.7 0.18 11.9 0.1 2.8 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 SspB PF04386.13 ORY13829.1 - 0.13 12.2 0.1 0.28 11.0 0.1 1.5 1 0 0 1 1 1 0 Stringent starvation protein B Syntaxin-6_N PF09177.11 ORY13829.1 - 5.6 7.6 9.4 80 3.9 3.1 4.0 1 1 2 3 3 3 0 Syntaxin 6, N-terminal Glyco_hydro_cc PF11790.8 ORY13830.1 - 6.1e-62 209.3 0.1 7.1e-62 209.1 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Ribosomal_L22 PF00237.19 ORY13831.1 - 9.3e-42 141.5 1.1 9.7e-42 141.4 0.1 1.5 2 0 0 2 2 2 1 Ribosomal protein L22p/L17e Fibrillarin PF01269.17 ORY13832.1 - 1.6e-104 348.0 0.0 1.9e-104 347.7 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 ORY13832.1 - 4.7e-06 26.5 0.0 6.7e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltr_RsmB-F PF01189.17 ORY13832.1 - 0.0049 16.5 0.0 0.02 14.5 0.0 1.8 2 0 0 2 2 2 1 16S rRNA methyltransferase RsmB/F PCMT PF01135.19 ORY13832.1 - 0.027 14.2 0.0 0.041 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RNR_inhib PF08591.10 ORY13833.1 - 9.8e-25 87.9 0.0 2.2e-24 86.8 0.0 1.6 1 0 0 1 1 1 1 Ribonucleotide reductase inhibitor Tricorn_PDZ PF14685.6 ORY13833.1 - 0.12 12.4 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Tricorn protease PDZ domain MFS_1 PF07690.16 ORY13834.1 - 3.9e-39 134.6 28.9 3.9e-39 134.6 28.9 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY13834.1 - 8.1e-11 41.4 15.6 1.3e-10 40.8 15.6 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter DUF4519 PF15012.6 ORY13834.1 - 2.1 8.6 0.0 2.1 8.6 0.0 3.0 4 0 0 4 4 4 0 Domain of unknown function (DUF4519) AAA_2 PF07724.14 ORY13835.1 - 6e-46 156.7 0.0 7.1e-45 153.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 ORY13835.1 - 2e-34 117.6 1.4 2e-34 117.6 1.4 3.9 4 1 1 5 5 4 1 AAA lid domain AAA PF00004.29 ORY13835.1 - 9.1e-27 94.1 0.0 7.1e-14 52.4 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 ORY13835.1 - 1.6e-22 79.3 0.4 1.6e-22 79.3 0.4 2.6 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 ORY13835.1 - 1.7e-15 57.2 0.0 7.5e-10 38.9 0.0 3.1 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 ORY13835.1 - 7.2e-14 52.2 0.2 2.6e-05 24.5 0.0 4.3 2 1 1 3 3 3 2 AAA domain AAA_16 PF13191.6 ORY13835.1 - 4e-11 43.6 13.7 7e-07 29.8 0.1 5.5 4 3 1 6 6 4 2 AAA ATPase domain Sigma54_activat PF00158.26 ORY13835.1 - 2.4e-08 33.9 0.0 1.7e-05 24.6 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_18 PF13238.6 ORY13835.1 - 6.4e-07 30.0 0.0 0.083 13.4 0.0 4.5 4 0 0 4 4 3 2 AAA domain IstB_IS21 PF01695.17 ORY13835.1 - 2.4e-06 27.4 0.0 0.078 12.7 0.0 2.9 3 0 0 3 3 2 2 IstB-like ATP binding protein Clp_N PF02861.20 ORY13835.1 - 2.9e-06 27.3 0.1 0.019 15.0 0.0 4.1 3 0 0 3 3 3 1 Clp amino terminal domain, pathogenicity island component AAA_7 PF12775.7 ORY13835.1 - 3.9e-06 26.5 0.0 0.012 15.1 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region ATPase_2 PF01637.18 ORY13835.1 - 5.1e-06 26.6 2.7 0.069 13.1 0.1 4.2 4 1 0 4 4 3 1 ATPase domain predominantly from Archaea TniB PF05621.11 ORY13835.1 - 5.5e-06 25.9 1.8 0.14 11.5 0.0 5.1 4 2 1 5 5 5 1 Bacterial TniB protein AAA_14 PF13173.6 ORY13835.1 - 8.8e-06 25.8 0.0 0.11 12.5 0.0 3.2 3 0 0 3 3 2 2 AAA domain AAA_33 PF13671.6 ORY13835.1 - 9.6e-06 25.8 0.0 0.27 11.4 0.0 3.4 2 1 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 ORY13835.1 - 1.2e-05 24.8 0.1 0.18 11.1 0.1 3.6 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 ORY13835.1 - 6.2e-05 23.3 0.0 0.5 10.8 0.0 2.6 2 0 0 2 2 2 2 RNA helicase AAA_30 PF13604.6 ORY13835.1 - 7e-05 22.6 0.0 0.66 9.7 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_3 PF07726.11 ORY13835.1 - 0.00015 21.6 0.0 0.97 9.3 0.0 3.3 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 ORY13835.1 - 0.00029 21.2 0.2 0.25 11.7 0.4 3.9 3 1 0 3 3 2 1 AAA domain TsaE PF02367.17 ORY13835.1 - 0.00037 20.5 0.0 0.46 10.5 0.0 2.6 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RsgA_GTPase PF03193.16 ORY13835.1 - 0.00039 20.4 0.0 0.91 9.4 0.0 2.9 3 0 0 3 3 2 1 RsgA GTPase AAA_28 PF13521.6 ORY13835.1 - 0.00041 20.6 5.6 0.65 10.2 0.0 4.0 3 1 0 3 3 3 2 AAA domain ABC_tran PF00005.27 ORY13835.1 - 0.00041 20.9 0.9 0.67 10.5 0.0 3.5 4 0 0 4 4 3 1 ABC transporter AAA_24 PF13479.6 ORY13835.1 - 0.0007 19.4 0.0 0.86 9.3 0.0 2.8 2 1 0 2 2 2 1 AAA domain T2SSE PF00437.20 ORY13835.1 - 0.0011 18.1 0.5 0.014 14.5 0.0 2.7 3 0 0 3 3 3 1 Type II/IV secretion system protein RuvB_N PF05496.12 ORY13835.1 - 0.0017 18.1 1.5 8 6.2 0.7 4.3 3 1 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain Torsin PF06309.11 ORY13835.1 - 0.0032 17.6 0.0 0.028 14.5 0.0 2.4 3 0 0 3 3 2 1 Torsin Zeta_toxin PF06414.12 ORY13835.1 - 0.004 16.4 0.0 0.61 9.3 0.0 2.8 2 0 0 2 2 2 1 Zeta toxin AAA_29 PF13555.6 ORY13835.1 - 0.0049 16.6 0.0 5.5 6.8 0.0 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain DHR10 PF18595.1 ORY13835.1 - 0.005 16.9 12.5 0.016 15.3 12.5 1.8 1 0 0 1 1 1 1 Designed helical repeat protein 10 domain NACHT PF05729.12 ORY13835.1 - 0.0061 16.5 0.1 0.55 10.1 0.0 2.9 3 0 0 3 3 2 1 NACHT domain Roc PF08477.13 ORY13835.1 - 0.0072 16.5 0.0 3 8.1 0.0 2.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase NTPase_1 PF03266.15 ORY13835.1 - 0.0074 16.2 0.0 0.28 11.1 0.0 3.0 3 0 0 3 3 3 1 NTPase SRP54 PF00448.22 ORY13835.1 - 0.0085 15.7 0.0 2 8.0 0.0 2.7 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain ResIII PF04851.15 ORY13835.1 - 0.0085 16.1 0.0 1.8 8.5 0.0 3.6 4 0 0 4 4 3 1 Type III restriction enzyme, res subunit GAS PF13851.6 ORY13835.1 - 0.012 15.0 12.1 0.031 13.6 12.1 1.7 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding AAA_25 PF13481.6 ORY13835.1 - 0.012 15.2 3.1 0.48 10.0 0.0 3.4 3 0 0 3 3 3 0 AAA domain BST2 PF16716.5 ORY13835.1 - 0.025 15.1 4.1 0.11 13.1 3.9 2.2 1 1 0 1 1 1 0 Bone marrow stromal antigen 2 Rad17 PF03215.15 ORY13835.1 - 0.032 14.1 0.0 9.8 6.1 0.0 2.7 3 0 0 3 3 2 0 Rad17 P-loop domain SRPRB PF09439.10 ORY13835.1 - 0.074 12.5 0.3 11 5.5 0.0 3.5 4 0 0 4 4 4 0 Signal recognition particle receptor beta subunit YlqD PF11068.8 ORY13835.1 - 0.16 12.3 2.9 0.58 10.5 2.9 2.0 1 0 0 1 1 1 0 YlqD protein AAA_21 PF13304.6 ORY13835.1 - 0.19 11.5 0.1 14 5.3 0.0 3.4 4 1 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system V_ATPase_I PF01496.19 ORY13835.1 - 0.22 9.4 1.3 0.34 8.8 1.3 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AAA_23 PF13476.6 ORY13835.1 - 0.39 11.2 0.0 0.39 11.2 0.0 5.1 4 2 0 5 5 3 0 AAA domain Spc7 PF08317.11 ORY13835.1 - 0.58 9.0 13.4 1.3 7.8 13.4 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein Macoilin PF09726.9 ORY13835.1 - 1.1 7.8 5.6 1.6 7.2 5.6 1.2 1 0 0 1 1 1 0 Macoilin family BRE1 PF08647.11 ORY13835.1 - 1.4 9.0 15.3 4.2 7.5 0.4 3.0 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase Nup54 PF13874.6 ORY13835.1 - 1.7 8.8 10.1 8.5 6.5 0.7 3.0 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 CorA PF01544.18 ORY13835.1 - 2.1 7.6 5.5 5.5 6.2 5.5 1.7 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Occludin_ELL PF07303.13 ORY13835.1 - 2.3 9.0 5.3 4.4 8.1 3.3 2.5 2 0 0 2 2 1 0 Occludin homology domain Exonuc_VII_L PF02601.15 ORY13835.1 - 3 7.3 7.3 0.61 9.6 3.7 1.7 2 0 0 2 2 1 0 Exonuclease VII, large subunit Sigma70_r1_1 PF03979.14 ORY13835.1 - 6.4 6.9 7.6 0.91 9.6 0.5 3.0 3 0 0 3 3 1 0 Sigma-70 factor, region 1.1 MARVEL PF01284.23 ORY13836.1 - 0.0013 18.8 2.6 0.002 18.2 2.6 1.3 1 0 0 1 1 1 1 Membrane-associating domain BPD_transp_1 PF00528.22 ORY13836.1 - 0.0067 16.2 4.5 0.033 13.9 0.8 2.1 2 0 0 2 2 2 2 Binding-protein-dependent transport system inner membrane component YqhR PF11085.8 ORY13836.1 - 0.048 13.6 0.4 0.081 12.9 0.4 1.3 1 0 0 1 1 1 0 Conserved membrane protein YqhR Claudin_2 PF13903.6 ORY13836.1 - 0.14 11.9 3.3 0.098 12.4 0.8 2.0 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction UBA_4 PF14555.6 ORY13838.1 - 0.0076 16.0 0.1 0.014 15.2 0.1 1.3 1 0 0 1 1 1 1 UBA-like domain LysM PF01476.20 ORY13838.1 - 0.021 14.9 0.0 0.042 13.9 0.0 1.5 1 0 0 1 1 1 0 LysM domain TAP_C PF03943.13 ORY13838.1 - 0.19 11.4 0.0 0.37 10.4 0.0 1.5 1 0 0 1 1 1 0 TAP C-terminal domain Dynactin_p62 PF05502.13 ORY13838.1 - 0.8 8.4 4.6 1.2 7.8 4.6 1.2 1 0 0 1 1 1 0 Dynactin p62 family Ribosomal_S8 PF00410.19 ORY13839.1 - 6.8e-21 74.5 0.1 1e-20 74.0 0.1 1.3 1 1 0 1 1 1 1 Ribosomal protein S8 Spermine_synth PF01564.17 ORY13840.1 - 0.04 13.3 0.1 0.067 12.6 0.1 1.3 1 0 0 1 1 1 0 Spermine/spermidine synthase domain DUF2400 PF09674.10 ORY13841.1 - 0.057 13.4 0.9 0.18 11.8 0.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2400) SPX PF03105.19 ORY13843.1 - 1.4 8.7 10.9 1.6 8.6 10.9 1.2 1 0 0 1 1 1 0 SPX domain AstE_AspA PF04952.14 ORY13844.1 - 7.9e-22 77.7 0.0 5.1e-11 42.2 0.0 2.1 1 1 1 2 2 2 2 Succinylglutamate desuccinylase / Aspartoacylase family DUF4360 PF14273.6 ORY13845.1 - 5.8e-14 52.4 0.0 7.2e-14 52.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) SNF2_N PF00176.23 ORY13846.1 - 6e-59 199.5 0.0 8.9e-59 199.0 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ORY13846.1 - 2.1e-14 53.8 0.0 3.8e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY13846.1 - 2.4e-08 34.2 0.0 4.3e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 ORY13846.1 - 0.00052 19.3 0.0 0.0011 18.2 0.0 1.5 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 ORY13846.1 - 0.00062 19.6 0.0 0.0011 18.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 ORY13846.1 - 0.035 13.8 0.4 0.2 11.3 0.0 2.1 2 0 0 2 2 2 0 SWI2/SNF2 ATPase DUF2439 PF10382.9 ORY13846.1 - 0.21 11.9 0.4 0.54 10.6 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2439) PTPRCAP PF15713.5 ORY13846.1 - 0.46 10.8 3.9 0.79 10.0 3.9 1.4 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated FA_hydroxylase PF04116.13 ORY13848.1 - 9.8e-25 87.4 10.4 9.8e-25 87.4 10.4 2.3 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily TCTP PF00838.17 ORY13849.1 - 5.2e-73 244.8 0.9 5.8e-73 244.7 0.9 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein Mus7 PF09462.10 ORY13849.1 - 0.039 12.8 0.0 0.047 12.5 0.0 1.0 1 0 0 1 1 1 0 Mus7/MMS22 family Nse4-Nse3_bdg PF15412.6 ORY13849.1 - 0.13 12.4 0.0 0.31 11.2 0.0 1.6 1 0 0 1 1 1 0 Binding domain of Nse4/EID3 to Nse3-MAGE RdRP PF05183.12 ORY13850.1 - 1.6e-125 420.0 0.0 2.2e-125 419.6 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase PhyH PF05721.13 ORY13851.1 - 1.1e-08 35.6 0.0 2e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) UPF0524 PF15823.5 ORY13852.1 - 0.12 11.7 0.7 0.26 10.7 0.7 1.6 1 0 0 1 1 1 0 UPF0524 of C3orf70 Ribosomal_S25 PF03297.15 ORY13853.1 - 1.1e-36 125.1 5.0 1.3e-36 124.8 5.0 1.0 1 0 0 1 1 1 1 S25 ribosomal protein HTH_DeoR PF08220.12 ORY13853.1 - 0.0012 18.5 0.1 0.0016 18.1 0.1 1.2 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain HTH_24 PF13412.6 ORY13853.1 - 0.0017 17.8 0.1 0.0029 17.1 0.1 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR_2 PF12802.7 ORY13853.1 - 0.0066 16.3 0.1 0.0084 16.0 0.1 1.2 1 0 0 1 1 1 1 MarR family Rrf2 PF02082.20 ORY13853.1 - 0.02 15.2 0.1 0.027 14.8 0.1 1.2 1 0 0 1 1 1 0 Transcriptional regulator GntR PF00392.21 ORY13853.1 - 0.04 13.6 0.1 0.056 13.1 0.1 1.3 1 1 0 1 1 1 0 Bacterial regulatory proteins, gntR family EAP30 PF04157.16 ORY13853.1 - 0.073 12.4 0.0 0.084 12.1 0.0 1.1 1 0 0 1 1 1 0 EAP30/Vps36 family TrmB PF01978.19 ORY13853.1 - 0.085 12.7 0.1 0.12 12.3 0.1 1.2 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Peptidase_C12 PF01088.21 ORY13856.1 - 1e-47 162.6 0.0 1.4e-47 162.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Cupin_2 PF07883.11 ORY13857.1 - 1.4e-14 53.5 0.5 2e-14 53.0 0.5 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 ORY13857.1 - 0.0023 17.5 0.1 0.0032 17.1 0.1 1.2 1 0 0 1 1 1 1 Cupin CENP-C_C PF11699.8 ORY13857.1 - 0.037 14.2 0.0 0.08 13.2 0.0 1.6 2 0 0 2 2 2 0 Mif2/CENP-C like Cupin_3 PF05899.12 ORY13857.1 - 0.063 13.0 0.0 0.14 11.9 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF861) HSP70 PF00012.20 ORY13858.1 - 9.4e-63 212.3 3.0 1.7e-58 198.3 0.1 3.3 3 0 0 3 3 3 2 Hsp70 protein MreB_Mbl PF06723.13 ORY13858.1 - 0.08 11.7 0.2 0.22 10.3 0.1 1.8 2 0 0 2 2 2 0 MreB/Mbl protein DUF1117 PF06547.12 ORY13858.1 - 7.3 7.2 6.7 2 9.0 2.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1117) Mtc PF03820.17 ORY13859.1 - 6.1e-122 406.6 0.0 6.8e-122 406.4 0.0 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier Pectate_lyase_3 PF12708.7 ORY13862.1 - 1.7e-98 328.8 9.7 7.6e-87 290.7 6.6 2.8 2 0 0 2 2 2 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 ORY13862.1 - 4.4e-07 29.5 0.5 0.026 14.2 0.1 2.5 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Aminotran_1_2 PF00155.21 ORY13863.1 - 8.3e-16 58.1 0.0 1.6e-15 57.2 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II TruD PF01142.18 ORY13865.1 - 2.7e-57 194.5 0.7 2e-53 181.7 0.8 3.9 2 1 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) DUF3445 PF11927.8 ORY13866.1 - 5.9e-61 206.0 0.0 7.6e-61 205.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) CN_hydrolase PF00795.22 ORY13867.1 - 1.1e-32 113.4 0.0 1.4e-26 93.4 0.0 2.2 2 0 0 2 2 2 2 Carbon-nitrogen hydrolase PDEase_II PF02112.15 ORY13868.1 - 1.3e-52 179.0 0.0 1.8e-23 83.2 0.0 3.2 3 0 0 3 3 3 3 cAMP phosphodiesterases class-II EF1G PF00647.19 ORY13868.1 - 6.6e-47 158.0 0.3 1.5e-46 156.8 0.3 1.6 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.25 ORY13868.1 - 2.8e-14 53.1 0.0 2.8e-14 53.1 0.0 2.2 3 0 0 3 3 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 ORY13868.1 - 2.5e-10 40.2 0.1 8.6e-10 38.5 0.1 2.0 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 ORY13868.1 - 2.7e-10 40.5 0.1 7.9e-10 38.9 0.0 1.9 2 0 0 2 2 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 ORY13868.1 - 1.2e-05 25.6 0.0 2.7e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 ORY13868.1 - 4.4e-05 23.6 0.0 0.00014 21.9 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 ORY13868.1 - 0.013 15.2 0.0 4.6 7.1 0.0 2.7 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 ORY13868.1 - 0.02 15.2 0.0 0.046 14.0 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Lactamase_B_2 PF12706.7 ORY13868.1 - 0.1 12.1 0.1 0.68 9.4 0.1 2.2 1 1 0 1 1 1 0 Beta-lactamase superfamily domain Lactamase_B PF00753.27 ORY13868.1 - 0.53 10.3 3.4 0.26 11.3 0.1 2.2 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily Ribosomal_S9 PF00380.19 ORY13869.1 - 5.3e-41 139.9 0.2 8e-41 139.4 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S9/S16 DUF1041 PF06292.17 ORY13871.1 - 0.028 14.8 0.3 0.069 13.6 0.3 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1041) DUF3446 PF11928.8 ORY13871.1 - 0.88 9.9 0.0 0.88 9.9 0.0 3.3 3 1 0 3 3 3 0 Early growth response N-terminal domain Glyco_hydro_72 PF03198.14 ORY13888.1 - 1.4e-99 333.3 6.2 1.7e-99 333.0 6.2 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 ORY13888.1 - 1.7e-06 27.7 0.9 1.8e-05 24.3 0.9 2.4 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.17 ORY13888.1 - 0.018 14.2 0.6 0.07 12.2 0.6 1.9 1 1 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain AA_permease PF00324.21 ORY13890.1 - 5.3e-105 351.8 36.8 6.5e-105 351.5 36.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ORY13890.1 - 3.4e-25 88.8 40.0 4.3e-25 88.4 40.0 1.1 1 0 0 1 1 1 1 Amino acid permease Sigma_reg_N PF13800.6 ORY13890.1 - 0.58 10.5 0.0 0.58 10.5 0.0 3.0 4 0 0 4 4 4 0 Sigma factor regulator N-terminal DUF1772 PF08592.11 ORY13890.1 - 2.1 8.7 17.0 0.11 12.8 1.4 3.8 4 1 1 5 5 5 0 Domain of unknown function (DUF1772) DUF5102 PF17104.5 ORY13892.1 - 0.0053 16.9 0.5 0.0068 16.5 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF5102) AF-4 PF05110.13 ORY13892.1 - 0.016 13.4 14.7 0.018 13.2 14.7 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Macoilin PF09726.9 ORY13892.1 - 0.02 13.5 6.6 0.019 13.5 6.6 1.0 1 0 0 1 1 1 0 Macoilin family Menin PF05053.13 ORY13892.1 - 0.032 12.6 3.6 0.032 12.6 3.6 1.0 1 0 0 1 1 1 0 Menin RAP1 PF07218.11 ORY13892.1 - 0.089 11.1 3.9 0.081 11.2 3.9 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Zn_peptidase_2 PF04298.12 ORY13892.1 - 0.099 12.0 0.1 0.2 11.1 0.1 1.4 1 0 0 1 1 1 0 Putative neutral zinc metallopeptidase Presenilin PF01080.17 ORY13892.1 - 0.23 10.2 2.2 0.25 10.1 2.2 1.1 1 0 0 1 1 1 0 Presenilin Secretin_N_2 PF07655.13 ORY13892.1 - 0.39 11.3 21.9 0.59 10.7 21.9 1.3 1 0 0 1 1 1 0 Secretin N-terminal domain YABBY PF04690.13 ORY13892.1 - 1.2 9.7 9.2 0.092 13.3 4.5 1.5 2 0 0 2 2 2 0 YABBY protein SSP160 PF06933.11 ORY13892.1 - 1.5 7.0 17.8 1.6 6.8 17.8 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 CCDC106 PF15794.5 ORY13892.1 - 3.9 7.1 11.3 1.1 8.9 7.4 1.8 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 Corona_nucleoca PF00937.18 ORY13892.1 - 7.3 5.5 13.5 9 5.2 13.5 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein DUF4663 PF15668.5 ORY13892.1 - 9.4 5.2 8.6 13 4.7 8.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4663) Hydantoinase_B PF02538.14 ORY13894.1 - 8.1e-130 433.6 0.0 1.3e-129 433.0 0.0 1.3 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 ORY13894.1 - 4.4e-87 292.0 7.2 1.9e-86 289.9 3.7 2.6 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 ORY13894.1 - 3.6e-48 163.6 0.3 2.2e-45 154.5 0.0 2.5 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region MutL PF13941.6 ORY13894.1 - 0.0076 14.9 2.0 0.81 8.2 0.3 2.5 2 1 0 2 2 2 2 MutL protein BcrAD_BadFG PF01869.20 ORY13894.1 - 0.018 14.5 0.6 2.5 7.5 0.0 2.4 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family FtsA PF14450.6 ORY13894.1 - 0.17 12.3 1.0 24 5.4 0.1 3.0 2 1 0 2 2 2 0 Cell division protein FtsA Aa_trans PF01490.18 ORY13895.1 - 2.9e-17 62.5 17.0 3.9e-17 62.1 17.0 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Polysacc_deac_1 PF01522.21 ORY13896.1 - 2.2e-11 43.7 0.0 4e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Amidase PF01425.21 ORY13897.1 - 1e-86 291.7 0.0 1.3e-86 291.4 0.0 1.0 1 0 0 1 1 1 1 Amidase Sugar_tr PF00083.24 ORY13900.1 - 6.4e-32 111.0 22.0 1.1e-24 87.1 7.7 2.5 1 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 ORY13900.1 - 4.6e-30 104.7 28.6 8e-26 90.8 10.8 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily LacY_symp PF01306.19 ORY13900.1 - 1.6e-05 23.9 9.7 3.6e-05 22.7 9.7 1.6 1 1 0 1 1 1 1 LacY proton/sugar symporter DUF4046 PF13255.6 ORY13900.1 - 0.11 13.0 0.0 0.58 10.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4046) MFS_1 PF07690.16 ORY13901.1 - 5e-36 124.4 49.9 6.8e-36 123.9 45.7 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily AIG2_2 PF13772.6 ORY13902.1 - 2.7e-07 30.9 0.0 4.8e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 AIG2-like family SieB PF14163.6 ORY13902.1 - 0.00078 19.0 0.0 0.0011 18.5 0.0 1.2 1 0 0 1 1 1 1 Super-infection exclusion protein B GGACT PF06094.12 ORY13902.1 - 0.0037 17.9 0.0 0.0056 17.3 0.0 1.3 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like Peptidase_M19 PF01244.21 ORY13903.1 - 2.5e-96 322.6 0.3 2.9e-96 322.4 0.3 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Methyltransf_23 PF13489.6 ORY13904.1 - 2.4e-09 37.2 0.0 3.3e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY13904.1 - 1.6e-08 34.5 0.0 2.7e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY13904.1 - 5.4e-07 30.2 0.0 1.1e-06 29.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY13904.1 - 0.00035 21.2 0.0 0.00069 20.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY13904.1 - 0.0023 18.5 0.0 0.0045 17.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 ORY13904.1 - 0.0028 17.8 0.0 0.014 15.5 0.0 1.8 1 1 1 2 2 2 1 FtsJ-like methyltransferase CheR PF01739.18 ORY13904.1 - 0.0064 16.0 0.0 0.0095 15.4 0.0 1.3 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain p450 PF00067.22 ORY13905.1 - 3.5e-32 111.8 0.0 4.2e-32 111.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_23 PF13489.6 ORY13906.1 - 2.9e-10 40.2 0.0 3.9e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY13906.1 - 6.1e-07 29.4 0.0 8.9e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY13906.1 - 1e-05 26.1 0.0 2e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY13906.1 - 0.0052 17.5 0.0 0.0091 16.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY13906.1 - 0.014 16.0 0.0 0.026 15.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PKD_channel PF08016.12 ORY13907.1 - 0.012 14.3 8.0 0.018 13.7 8.0 1.2 1 0 0 1 1 1 0 Polycystin cation channel GST_N_3 PF13417.6 ORY13908.1 - 5.1e-07 30.0 0.0 1.1e-06 29.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 ORY13908.1 - 2.8e-06 27.6 0.1 7.8e-06 26.1 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 ORY13908.1 - 0.00013 22.1 0.0 0.0003 20.9 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 ORY13908.1 - 0.042 14.0 0.0 0.077 13.2 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 ORY13908.1 - 0.066 13.2 0.4 0.14 12.2 0.4 1.8 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 ORY13908.1 - 0.13 13.1 0.0 0.89 10.3 0.0 2.3 1 1 0 2 2 2 0 Glutathione S-transferase N-terminal domain p450 PF00067.22 ORY13909.1 - 6.8e-40 137.2 0.0 3.6e-39 134.8 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 Trp_DMAT PF11991.8 ORY13910.1 - 7.9e-77 259.1 0.0 1.1e-76 258.7 0.0 1.2 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase Aminotran_1_2 PF00155.21 ORY13911.1 - 7e-42 143.9 0.0 8.4e-42 143.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II AMP-binding PF00501.28 ORY13912.1 - 7.8e-148 492.5 0.0 9e-77 258.4 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.20 ORY13912.1 - 6.9e-68 229.4 0.0 1.1e-33 116.7 0.0 2.9 2 1 0 2 2 2 2 Condensation domain PP-binding PF00550.25 ORY13912.1 - 4.7e-17 62.1 0.4 4.3e-07 30.2 0.1 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.6 ORY13912.1 - 1.2e-06 29.4 0.0 0.0014 19.5 0.0 2.7 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain Zn_clus PF00172.18 ORY13913.1 - 1.4e-07 31.5 8.6 1.4e-07 31.5 8.6 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPP_enzyme_N PF02776.18 ORY13917.1 - 6.3e-29 100.8 0.1 7.6e-29 100.5 0.1 1.1 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain ER PF01133.17 ORY13917.1 - 0.17 11.9 0.1 0.29 11.2 0.1 1.3 1 0 0 1 1 1 0 Enhancer of rudimentary TPP_enzyme_C PF02775.21 ORY13918.1 - 1.5e-06 28.1 0.0 2e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain F-box-like PF12937.7 ORY13921.1 - 9.7e-05 22.2 0.5 0.00024 20.9 0.5 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY13921.1 - 0.0087 15.9 0.2 0.021 14.7 0.2 1.6 1 0 0 1 1 1 1 F-box domain TFR_dimer PF04253.15 ORY13927.1 - 3e-29 101.6 0.0 6e-29 100.6 0.0 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 ORY13927.1 - 3.9e-21 75.7 0.1 9e-21 74.5 0.0 1.6 2 0 0 2 2 2 1 Peptidase family M28 PA PF02225.22 ORY13927.1 - 6.5e-10 38.9 0.6 3.3e-09 36.6 0.0 2.4 3 0 0 3 3 3 1 PA domain Telomerase_RBD PF12009.8 ORY13927.1 - 0.066 13.3 0.1 0.11 12.6 0.1 1.3 1 0 0 1 1 1 0 Telomerase ribonucleoprotein complex - RNA binding domain Nicastrin PF05450.15 ORY13927.1 - 0.18 11.2 0.0 0.33 10.4 0.0 1.3 1 0 0 1 1 1 0 Nicastrin PHD PF00628.29 ORY13928.1 - 0.008 16.1 17.1 0.016 15.0 11.4 2.6 2 0 0 2 2 2 1 PHD-finger zf-RING_2 PF13639.6 ORY13928.1 - 0.017 15.5 9.6 0.017 15.5 9.6 2.3 2 0 0 2 2 2 0 Ring finger domain DUF29 PF01724.16 ORY13928.1 - 0.028 14.6 0.3 0.17 12.1 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function DUF29 PPP4R2 PF09184.11 ORY13928.1 - 0.44 10.1 11.0 0.93 9.0 11.0 1.5 1 0 0 1 1 1 0 PPP4R2 Nup160 PF11715.8 ORY13932.1 - 0.0006 18.6 0.1 0.0006 18.6 0.1 1.0 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Chlorophyllase2 PF12740.7 ORY13938.1 - 3.9e-06 26.0 0.0 5.4e-06 25.5 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase enzyme DLH PF01738.18 ORY13938.1 - 0.00043 19.9 0.5 0.0008 19.0 0.5 1.5 1 1 0 1 1 1 1 Dienelactone hydrolase family Chlorophyllase PF07224.11 ORY13938.1 - 0.0095 15.0 0.1 0.013 14.5 0.1 1.2 1 0 0 1 1 1 1 Chlorophyllase Abhydrolase_2 PF02230.16 ORY13938.1 - 0.032 14.0 0.1 0.047 13.5 0.1 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase PAF-AH_p_II PF03403.13 ORY13938.1 - 0.035 12.6 0.2 3.1 6.2 0.0 2.1 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II DUF1749 PF08538.10 ORY13938.1 - 0.079 12.0 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Abhydrolase_3 PF07859.13 ORY13938.1 - 0.13 12.1 0.3 0.21 11.4 0.3 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold GAGBD PF16828.5 ORY13939.1 - 0.069 13.3 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 GAG-binding domain on surface antigen Fungal_trans_2 PF11951.8 ORY13940.1 - 7.6e-44 150.1 1.6 1e-43 149.6 1.6 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY13940.1 - 2.8e-07 30.6 8.5 5.3e-07 29.7 8.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short_C2 PF13561.6 ORY13941.1 - 1.1e-08 34.9 0.1 1.3e-08 34.7 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY13941.1 - 4.1e-06 26.4 0.1 6e-06 25.8 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 ORY13941.1 - 0.0094 15.4 0.0 0.015 14.7 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 ORY13941.1 - 0.067 12.3 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain HECT PF00632.25 ORY13943.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 HECT-domain (ubiquitin-transferase) Slx4 PF09494.10 ORY13946.1 - 1.2e-17 63.6 3.6 1.2e-12 47.5 0.2 2.4 2 0 0 2 2 2 2 Slx4 endonuclease AA_permease PF00324.21 ORY13948.1 - 3.4e-132 441.4 44.4 4.2e-132 441.1 44.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ORY13948.1 - 2.6e-34 118.8 45.3 3.3e-34 118.4 45.3 1.1 1 0 0 1 1 1 1 Amino acid permease SH3_1 PF00018.28 ORY13950.1 - 1.8e-09 37.0 0.0 3.4e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 ORY13950.1 - 2e-09 37.1 0.1 2e-09 37.1 0.1 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 ORY13950.1 - 1.1e-05 25.1 0.0 2.2e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Ssu72 PF04722.13 ORY13953.1 - 7e-78 260.6 0.0 8.1e-78 260.4 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein Fungal_lectin_2 PF18647.1 ORY13956.1 - 1.3e-10 41.7 0.2 6.7e-10 39.3 0.0 2.2 2 0 0 2 2 2 1 Alpha-galactosyl-binding fungal lectin Claudin_2 PF13903.6 ORY13958.1 - 0.03 14.1 0.1 0.047 13.5 0.1 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Asp_protease_2 PF13650.6 ORY13959.1 - 7.3e-05 23.3 0.0 0.28 11.9 0.0 2.9 2 0 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 ORY13959.1 - 0.0017 18.9 0.0 2.4 8.8 0.0 2.8 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease Dioxygenase_C PF00775.21 ORY13960.1 - 2.7e-05 23.7 0.1 4.6e-05 22.9 0.1 1.4 1 0 0 1 1 1 1 Dioxygenase BNR_2 PF13088.6 ORY13961.1 - 7.9e-05 22.1 0.2 0.00089 18.6 0.1 2.4 2 1 0 2 2 2 1 BNR repeat-like domain BNR PF02012.20 ORY13961.1 - 0.00058 19.5 1.9 0.83 9.9 0.4 3.4 2 0 0 2 2 2 2 BNR/Asp-box repeat Sortilin-Vps10 PF15902.5 ORY13961.1 - 0.011 14.5 0.3 1.4 7.7 0.0 2.5 3 0 0 3 3 3 0 Sortilin, neurotensin receptor 3, Transp_cyt_pur PF02133.15 ORY13963.1 - 1.3e-39 136.2 36.1 1.7e-39 135.9 36.1 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin HET PF06985.11 ORY13965.1 - 1.9e-27 96.4 0.1 3.4e-27 95.6 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HET PF06985.11 ORY13966.1 - 2.6e-30 105.7 0.0 7.6e-30 104.2 0.0 1.9 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF3953 PF13129.6 ORY13967.1 - 0.34 10.7 7.8 3.2 7.6 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3953) HET PF06985.11 ORY13968.1 - 4.2e-29 101.8 0.3 5.1e-29 101.5 0.3 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Phage_tail_U PF06141.11 ORY13968.1 - 0.018 15.4 0.0 0.025 14.9 0.0 1.2 1 0 0 1 1 1 0 Phage minor tail protein U Ribosomal_S19e PF01090.19 ORY13969.1 - 7.1e-57 190.9 0.2 8.1e-57 190.8 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e ILVD_EDD PF00920.21 ORY13970.1 - 5.8e-206 685.1 2.9 6.7e-206 684.9 2.9 1.0 1 0 0 1 1 1 1 Dehydratase family Abhydrolase_6 PF12697.7 ORY13971.1 - 1.3e-16 61.9 1.0 2.3e-16 61.1 0.4 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ORY13971.1 - 3.4e-12 46.6 0.0 1e-11 45.0 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ORY13971.1 - 7.7e-12 45.0 0.0 1.6e-11 43.9 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DSPc PF00782.20 ORY13971.1 - 5.2e-11 42.5 0.0 9.7e-11 41.6 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PGAP1 PF07819.13 ORY13971.1 - 6.9e-05 22.7 0.0 0.00098 18.9 0.0 2.1 2 0 0 2 2 2 1 PGAP1-like protein Y_phosphatase PF00102.27 ORY13971.1 - 8.9e-05 22.2 0.0 0.0002 21.0 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Thioesterase PF00975.20 ORY13971.1 - 0.0048 17.1 0.2 0.0086 16.2 0.2 1.3 1 0 0 1 1 1 1 Thioesterase domain PTPlike_phytase PF14566.6 ORY13971.1 - 0.013 15.6 0.0 0.021 14.9 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate Ser_hydrolase PF06821.13 ORY13971.1 - 0.045 13.6 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Serine hydrolase FSH1 PF03959.13 ORY13971.1 - 0.068 12.8 0.0 0.21 11.2 0.0 1.7 1 1 0 1 1 1 0 Serine hydrolase (FSH1) LCAT PF02450.15 ORY13971.1 - 0.07 12.3 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Esterase PF00756.20 ORY13971.1 - 0.13 11.9 0.1 0.27 10.8 0.1 1.4 1 0 0 1 1 1 0 Putative esterase Frizzled PF01534.17 ORY13971.1 - 0.15 11.0 0.1 0.56 9.2 0.1 1.8 2 0 0 2 2 2 0 Frizzled/Smoothened family membrane region Lipase_3 PF01764.25 ORY13971.1 - 0.19 11.6 0.1 0.39 10.6 0.1 1.4 1 0 0 1 1 1 0 Lipase (class 3) C2 PF00168.30 ORY13996.1 - 8.9e-17 61.3 0.0 1.4e-16 60.6 0.0 1.3 1 0 0 1 1 1 1 C2 domain CDP-OH_P_transf PF01066.21 ORY13997.1 - 0.087 13.6 0.0 0.12 13.2 0.0 1.4 1 1 0 1 1 1 0 CDP-alcohol phosphatidyltransferase Ribonucleas_3_3 PF14622.6 ORY13998.1 - 1.3e-06 28.6 0.0 1.5e-06 28.4 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 ORY13998.1 - 3.3e-05 24.4 0.2 0.00019 22.0 0.2 1.9 1 1 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 ORY13999.1 - 2.9e-10 40.4 0.0 4.9e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 ORY13999.1 - 4.3e-09 36.9 0.0 4.9e-08 33.5 0.0 2.4 2 1 0 2 2 2 1 Ribonuclease III domain Planc_extracel PF07595.12 ORY14001.1 - 0.37 10.7 4.3 1.1 9.2 4.3 1.8 1 0 0 1 1 1 0 Planctomycete extracellular RSN1_7TM PF02714.15 ORY14002.1 - 7.5e-87 291.1 26.6 1e-85 287.4 23.5 2.2 2 0 0 2 2 2 2 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 ORY14002.1 - 2e-45 154.4 3.0 2e-45 154.4 3.0 2.5 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 ORY14002.1 - 3.4e-30 105.6 0.1 5.8e-30 104.8 0.1 1.4 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 ORY14002.1 - 5.1e-22 77.8 0.0 1.1e-21 76.8 0.0 1.6 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter DUF3377 PF11857.8 ORY14002.1 - 0.4 10.7 4.3 0.68 9.9 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) Holin_BlyA PF05102.12 ORY14002.1 - 8.4 6.4 6.6 35 4.5 0.1 3.0 2 0 0 2 2 2 0 holin, BlyA family Pkinase PF00069.25 ORY14003.1 - 1.8e-67 227.5 0.0 2.1e-67 227.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY14003.1 - 3.9e-32 111.6 0.0 5.3e-32 111.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 ORY14003.1 - 0.0046 15.9 0.0 0.021 13.8 0.0 2.1 2 1 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 ORY14003.1 - 0.038 13.9 0.1 0.14 12.1 0.0 1.9 3 0 0 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.14 ORY14003.1 - 0.05 13.0 0.1 0.11 11.9 0.1 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Asp PF00026.23 ORY14004.1 - 3.7e-07 29.9 0.2 4.9e-06 26.2 0.2 2.0 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 ORY14004.1 - 0.0022 18.2 0.1 0.0055 17.0 0.1 1.6 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal MFS_1 PF07690.16 ORY14006.1 - 5.7e-18 65.0 37.8 7.5e-09 35.0 17.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4834 PF16118.5 ORY14006.1 - 0.052 14.5 0.1 0.16 12.9 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) UPF0242 PF06785.11 ORY14006.1 - 0.55 10.3 1.2 15 5.6 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Tyrosinase PF00264.20 ORY14007.1 - 4.9e-46 157.8 5.0 6.7e-46 157.3 5.0 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase NACHT PF05729.12 ORY14009.1 - 0.066 13.1 2.0 0.19 11.6 2.0 1.7 1 1 0 1 1 1 0 NACHT domain Peptidase_C15 PF01470.17 ORY14011.1 - 2.4e-16 60.5 0.0 8.5e-11 42.4 0.0 2.1 2 0 0 2 2 2 2 Pyroglutamyl peptidase EPSP_synthase PF00275.20 ORY14013.1 - 5.7e-126 420.6 0.0 7.5e-126 420.2 0.0 1.1 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.20 ORY14013.1 - 1.6e-102 342.1 0.1 2.7e-102 341.4 0.1 1.4 1 0 0 1 1 1 1 3-dehydroquinate synthase DHquinase_I PF01487.15 ORY14013.1 - 7.8e-57 193.1 0.0 1.4e-56 192.3 0.0 1.4 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.22 ORY14013.1 - 8.2e-35 120.3 0.0 9.8e-34 116.8 0.0 2.4 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.11 ORY14013.1 - 3.9e-19 68.7 0.0 8.4e-19 67.6 0.0 1.6 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 ORY14013.1 - 1.6e-10 40.5 0.1 4.8e-10 39.0 0.1 1.9 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Fe-ADH_2 PF13685.6 ORY14013.1 - 7.5e-07 29.1 0.0 1.8e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Shikimate_DH PF01488.20 ORY14013.1 - 0.055 13.5 0.0 0.18 11.9 0.0 1.8 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase AAA_33 PF13671.6 ORY14013.1 - 0.14 12.3 0.0 0.55 10.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain APH PF01636.23 ORY14015.1 - 8.6e-15 55.3 0.0 1.9e-13 50.9 0.0 2.5 2 1 0 2 2 2 1 Phosphotransferase enzyme family DUF1679 PF07914.11 ORY14015.1 - 0.068 12.0 0.0 5.3 5.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) Opy2 PF09463.10 ORY14018.1 - 0.35 11.2 9.1 0.56 10.6 9.1 1.4 1 0 0 1 1 1 0 Opy2 protein Dicty_REP PF05086.12 ORY14018.1 - 2.9 5.7 3.7 3.9 5.3 3.7 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Transthyretin PF00576.21 ORY14019.1 - 3.2e-34 117.9 0.0 3.9e-34 117.7 0.0 1.1 1 0 0 1 1 1 1 HIUase/Transthyretin family CarboxypepD_reg PF13620.6 ORY14019.1 - 0.046 14.0 0.5 1.3 9.3 0.4 2.7 1 1 1 2 2 2 0 Carboxypeptidase regulatory-like domain MG4 PF17789.1 ORY14019.1 - 0.07 13.3 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Macroglobulin domain MG4 Pyocin_S PF06958.12 ORY14019.1 - 7 7.2 8.1 6.1 7.4 1.5 3.1 2 1 2 4 4 4 0 S-type Pyocin ADH_zinc_N PF00107.26 ORY14020.1 - 1.2e-22 80.3 0.1 1.8e-22 79.7 0.1 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 ORY14020.1 - 3.6e-16 59.0 0.0 7.3e-16 58.0 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 ORY14020.1 - 6.1e-12 46.7 0.0 9.8e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase F-box-like PF12937.7 ORY14021.1 - 2.7e-05 24.0 0.5 6.3e-05 22.8 0.5 1.7 1 0 0 1 1 1 1 F-box-like DUF4360 PF14273.6 ORY14022.1 - 2.4e-25 89.5 0.0 2.5e-25 89.4 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) ATP_transf PF09830.9 ORY14023.1 - 7.5e-11 42.0 0.0 1.5e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 ATP adenylyltransferase TPPK_C PF12555.8 ORY14024.1 - 0.0068 16.4 2.1 0.018 15.1 2.1 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphokinase C terminal P21-Arc PF04062.14 ORY14024.1 - 0.02 14.9 0.0 0.055 13.5 0.0 1.7 1 0 0 1 1 1 0 ARP2/3 complex ARPC3 (21 kDa) subunit Aft1_HRA PF11786.8 ORY14026.1 - 2e-22 79.3 10.7 2e-22 79.3 10.7 3.8 3 1 1 4 4 4 1 Aft1 HRA domain Aft1_OSA PF11785.8 ORY14026.1 - 4.6e-15 55.8 13.7 4.6e-15 55.8 13.7 4.1 4 0 0 4 4 4 1 Aft1 osmotic stress response (OSM) domain Aft1_HRR PF11787.8 ORY14026.1 - 3.3e-14 53.8 11.2 3.3e-14 53.8 11.2 3.7 3 1 0 3 3 3 1 Aft1 HRR domain bZIP_1 PF00170.21 ORY14026.1 - 4.8e-12 45.8 3.7 8e-12 45.1 3.7 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 ORY14026.1 - 6.6e-05 22.9 4.1 0.00014 21.9 4.1 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 ORY14026.1 - 0.02 15.4 2.1 0.02 15.4 2.1 2.7 3 0 0 3 3 3 0 bZIP Maf transcription factor zf-MYND PF01753.18 ORY14027.1 - 7.7e-10 38.7 12.3 7.7e-10 38.7 12.3 2.9 3 0 0 3 3 3 2 MYND finger zf-Mss51 PF13824.6 ORY14027.1 - 3.5 7.8 7.5 0.34 11.0 0.2 2.7 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 AAA PF00004.29 ORY14028.1 - 3.8e-17 63.0 0.0 7.5e-17 62.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Torsin PF06309.11 ORY14028.1 - 0.0018 18.4 0.0 0.0036 17.4 0.0 1.5 1 0 0 1 1 1 1 Torsin AAA_16 PF13191.6 ORY14028.1 - 0.02 15.3 0.2 0.053 13.9 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 ORY14028.1 - 0.053 13.8 0.2 1.3 9.3 0.1 2.3 1 1 1 2 2 2 0 AAA domain AAA_33 PF13671.6 ORY14028.1 - 0.09 12.9 0.1 0.18 11.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.14 ORY14028.1 - 0.13 12.3 0.0 0.28 11.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 ORY14028.1 - 0.16 11.7 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Acetyltransf_3 PF13302.7 ORY14030.1 - 1.2e-12 48.7 0.0 1.6e-12 48.3 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORY14030.1 - 6.4e-11 42.5 0.0 9.9e-11 41.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ORY14030.1 - 3.3e-06 27.4 0.1 5.3e-06 26.8 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 ORY14030.1 - 0.0017 18.0 0.0 0.0034 17.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ORY14030.1 - 0.0035 17.3 0.0 0.0064 16.4 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 ORY14030.1 - 0.0072 16.3 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 ORY14030.1 - 0.012 15.8 0.0 0.02 15.0 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Enamelin PF15362.6 ORY14030.1 - 5.8 5.1 7.0 7.4 4.8 7.0 1.0 1 0 0 1 1 1 0 Enamelin zf-RING_2 PF13639.6 ORY14031.1 - 1.7e-08 34.6 2.3 4.2e-08 33.4 2.3 1.7 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 ORY14031.1 - 2e-07 31.1 1.2 5.3e-07 29.8 1.2 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 ORY14031.1 - 1.4e-06 28.0 2.2 2.7e-06 27.2 2.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 ORY14031.1 - 0.00064 19.7 1.3 0.0014 18.7 1.3 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 ORY14031.1 - 0.0017 18.3 1.4 0.0038 17.2 1.4 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 ORY14031.1 - 0.0035 17.3 3.4 0.0064 16.4 3.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 ORY14031.1 - 0.0063 16.2 3.6 0.0063 16.2 3.6 2.1 2 0 0 2 2 2 1 RING-like zinc finger Prok-RING_4 PF14447.6 ORY14031.1 - 0.0084 15.9 2.1 0.02 14.8 2.1 1.7 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 RINGv PF12906.7 ORY14031.1 - 0.024 14.7 2.4 0.056 13.6 2.4 1.7 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_2 PF13923.6 ORY14031.1 - 0.16 11.9 9.3 1.2 9.0 9.3 2.4 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 ORY14031.1 - 1.6 8.7 6.6 3.7 7.5 6.6 1.6 1 1 0 1 1 1 0 PHD-finger Zn_ribbon_17 PF17120.5 ORY14031.1 - 2.2 8.0 5.8 6.2 6.5 5.9 1.8 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 ORY14031.1 - 5.5 7.3 6.7 14 5.9 6.7 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain GST_N_2 PF13409.6 ORY14032.1 - 4e-21 75.1 0.0 7.7e-21 74.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 ORY14032.1 - 2.8e-13 49.7 0.0 8.9e-13 48.1 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 ORY14032.1 - 0.0003 21.0 0.0 0.0006 20.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 ORY14032.1 - 0.00063 19.9 0.0 0.0015 18.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 ORY14032.1 - 0.005 17.2 0.0 0.051 14.0 0.0 2.3 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 ORY14032.1 - 0.11 12.3 0.0 0.22 11.3 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Glyco_hydro_2_C PF02836.17 ORY14033.1 - 4.4e-15 55.6 0.1 1.3e-13 50.8 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.18 ORY14033.1 - 1.8e-14 54.0 1.7 6.7e-14 52.1 1.7 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.21 ORY14033.1 - 6.6e-11 42.9 0.1 3.7e-10 40.5 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.6 ORY14033.1 - 0.04 14.5 1.3 0.083 13.5 0.5 2.0 2 0 0 2 2 2 0 Beta-galactosidase jelly roll domain Pkinase PF00069.25 ORY14034.1 - 2.1e-19 69.9 0.0 1.2e-12 47.8 0.0 2.5 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORY14034.1 - 2.9e-10 39.9 0.0 2e-07 30.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase DUF2256 PF10013.9 ORY14035.1 - 7.5e-05 22.8 3.2 0.00026 21.1 3.2 2.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2256) zf-MYND PF01753.18 ORY14035.1 - 0.12 12.5 6.3 0.26 11.4 6.3 1.5 1 0 0 1 1 1 0 MYND finger zinc_ribbon_9 PF14369.6 ORY14035.1 - 0.16 12.3 2.6 0.31 11.3 2.6 1.6 1 0 0 1 1 1 0 zinc-ribbon Bys1 PF04681.12 ORY14036.1 - 1.3e-10 41.4 0.9 1.6e-10 41.1 0.9 1.0 1 0 0 1 1 1 1 Blastomyces yeast-phase-specific protein Glyco_hydro_72 PF03198.14 ORY14037.1 - 9.3e-99 330.6 0.3 1.3e-98 330.2 0.3 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Glyco_hydro_2_C PF02836.17 ORY14037.1 - 0.13 11.3 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain F-box-like PF12937.7 ORY14038.1 - 2.7e-05 24.0 1.4 5.3e-05 23.0 0.5 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 ORY14038.1 - 0.00071 19.4 0.0 0.0017 18.2 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 ORY14038.1 - 0.0042 17.0 0.1 0.07 13.0 0.0 2.2 2 0 0 2 2 2 1 F-box EAF PF09816.9 ORY14039.1 - 2.3e-17 63.3 2.5 7.2e-17 61.6 2.5 1.9 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor CAF1-p150_C2 PF15539.6 ORY14039.1 - 6.9 6.0 11.3 0.07 12.6 1.7 2.5 3 0 0 3 3 3 0 CAF1 complex subunit p150, region binding to CAF1-p60 at C-term Ribosomal_S2 PF00318.20 ORY14040.1 - 1.7e-26 92.8 0.2 4.9e-15 55.4 0.1 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 ORY14040.1 - 4.7e-09 37.5 13.4 7e-09 36.9 12.8 1.6 1 1 0 1 1 1 1 40S ribosomal protein SA C-terminus Ribosomal_S15 PF00312.22 ORY14041.1 - 3.9e-24 84.7 1.7 4.9e-24 84.4 0.2 2.0 2 0 0 2 2 2 1 Ribosomal protein S15 WSC PF01822.19 ORY14042.1 - 3.4e-51 171.4 48.9 6.2e-18 64.8 11.8 3.6 3 0 0 3 3 3 3 WSC domain peroxidase PF00141.23 ORY14042.1 - 6.9e-18 65.2 0.1 1.5e-17 64.1 0.1 1.5 1 0 0 1 1 1 1 Peroxidase A_deaminase PF00962.22 ORY14043.1 - 1.4e-53 182.4 0.0 1.6e-53 182.2 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase Amidohydro_3 PF07969.11 ORY14043.1 - 0.055 12.9 0.0 0.076 12.5 0.0 1.2 1 0 0 1 1 1 0 Amidohydrolase family HET PF06985.11 ORY14044.1 - 1.7e-07 31.7 0.1 3.3e-05 24.3 0.0 2.7 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) DUF418 PF04235.12 ORY14044.1 - 0.12 12.3 0.8 0.23 11.4 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF418) PLAC8 PF04749.17 ORY14045.1 - 1.2e-21 77.5 17.1 1.5e-21 77.3 17.1 1.1 1 0 0 1 1 1 1 PLAC8 family GrpB PF04229.14 ORY14047.1 - 1.4e-38 132.6 0.0 2.2e-38 132.0 0.0 1.3 1 0 0 1 1 1 1 GrpB protein Acetyltransf_3 PF13302.7 ORY14047.1 - 7.9e-19 68.7 0.0 1.2e-18 68.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORY14047.1 - 0.00011 22.4 0.0 0.00019 21.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 ORY14047.1 - 0.058 13.5 0.0 0.14 12.3 0.0 1.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain REV PF00424.18 ORY14048.1 - 0.053 13.6 0.1 0.096 12.7 0.1 1.5 1 0 0 1 1 1 0 REV protein (anti-repression trans-activator protein) FTHFS PF01268.19 ORY14052.1 - 1.6e-252 838.6 0.0 2.4e-252 838.1 0.0 1.2 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.19 ORY14052.1 - 2.2e-66 222.1 1.6 2.2e-66 222.1 1.6 1.7 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 ORY14052.1 - 2.7e-21 76.0 0.2 6.2e-21 74.8 0.2 1.7 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain CbiA PF01656.23 ORY14052.1 - 0.034 14.2 0.2 0.92 9.6 0.1 2.5 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Helicase_C_4 PF13871.6 ORY14052.1 - 0.14 11.8 0.0 0.22 11.2 0.0 1.2 1 0 0 1 1 1 0 C-terminal domain on Strawberry notch homologue WD40 PF00400.32 ORY14055.1 - 9e-22 77.0 2.1 3.6e-06 27.6 0.0 6.2 5 1 1 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY14055.1 - 8.2e-10 38.9 0.0 0.018 15.3 0.0 4.5 3 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 ORY14055.1 - 0.00024 20.6 0.0 0.053 12.8 0.0 2.6 3 0 0 3 3 3 2 WD40-like domain eIF2A PF08662.11 ORY14055.1 - 0.0022 17.9 0.0 2.2 8.1 0.0 2.6 2 2 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.6 ORY14055.1 - 0.0032 17.1 0.2 0.028 14.0 0.2 2.5 1 1 0 1 1 1 1 PQQ-like domain Gmad1 PF10647.9 ORY14055.1 - 0.0079 16.0 0.1 0.018 14.8 0.1 1.6 1 1 0 1 1 1 1 Lipoprotein LpqB beta-propeller domain DUF5046 PF16465.5 ORY14055.1 - 0.018 14.5 0.1 0.23 10.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5046) Nup160 PF11715.8 ORY14055.1 - 0.031 12.9 0.1 0.11 11.1 0.0 1.7 1 1 0 2 2 2 0 Nucleoporin Nup120/160 His_Phos_1 PF00300.22 ORY14056.1 - 7e-08 32.4 0.4 3.6e-07 30.1 0.0 2.2 2 1 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) Iso_dh PF00180.20 ORY14057.1 - 3.4e-73 246.8 0.0 3.9e-73 246.6 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase RhoGEF PF00621.20 ORY14059.1 - 6.1e-09 36.4 0.0 1.5e-08 35.1 0.0 1.7 2 0 0 2 2 2 1 RhoGEF domain Helo_like_N PF17111.5 ORY14059.1 - 7.7e-05 22.1 1.4 7.7e-05 22.1 1.4 2.4 2 0 0 2 2 2 1 Fungal N-terminal domain of STAND proteins Lactamase_B PF00753.27 ORY14060.1 - 6.5e-06 26.3 0.6 1.2e-05 25.5 0.6 1.7 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 ORY14060.1 - 0.00012 21.7 0.0 0.00026 20.6 0.0 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain ADH_N PF08240.12 ORY14061.1 - 1.2e-17 63.7 0.3 3.3e-17 62.4 0.3 1.7 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORY14061.1 - 4.4e-17 62.3 0.2 6.9e-17 61.6 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Fungal_trans PF04082.18 ORY14062.1 - 2.9e-16 59.3 0.4 2.9e-15 56.0 0.4 2.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 ORY14062.1 - 4.9e-08 33.0 13.6 0.00026 21.3 2.2 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY14062.1 - 3.8e-07 30.3 13.6 6.9e-07 29.4 1.4 3.6 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORY14062.1 - 0.00021 21.9 10.9 0.038 14.8 3.6 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORY14062.1 - 0.028 14.7 3.2 4.2 7.8 1.3 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 ORY14062.1 - 0.13 12.0 9.4 1.7 8.5 0.4 2.5 2 0 0 2 2 2 0 zinc-finger C2H2-type zf_C2H2_ZHX PF18387.1 ORY14062.1 - 0.21 11.2 5.9 1.8 8.3 0.5 2.7 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain CMD PF02627.20 ORY14063.1 - 8.3e-19 67.4 0.2 1.3e-18 66.8 0.2 1.3 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family TFX_C PF14601.6 ORY14063.1 - 0.12 12.4 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 DNA_binding protein, TFX, C-term NAD_binding_2 PF03446.15 ORY14064.1 - 1.8e-28 99.7 0.0 2.5e-28 99.3 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 ORY14064.1 - 2.1e-20 73.2 0.0 3.7e-20 72.4 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Lactamase_B PF00753.27 ORY14065.1 - 7.7e-11 42.4 1.7 2.3e-10 40.8 1.7 1.8 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily CMD PF02627.20 ORY14065.1 - 5.2e-09 36.0 0.0 0.0036 17.3 0.0 2.5 2 0 0 2 2 2 2 Carboxymuconolactone decarboxylase family Lactamase_B_2 PF12706.7 ORY14065.1 - 0.0027 17.2 0.0 0.0061 16.1 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain MFS_1 PF07690.16 ORY14066.1 - 1.2e-27 96.7 33.1 3e-24 85.6 19.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily VIT1 PF01988.19 ORY14066.1 - 2.7 7.8 13.9 5.4 6.8 0.0 3.2 2 2 2 4 4 4 0 VIT family NAD_binding_2 PF03446.15 ORY14067.1 - 1.5e-31 109.7 0.5 1.5e-31 109.7 0.5 1.5 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 ORY14067.1 - 3.7e-23 82.1 0.0 6.2e-23 81.4 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase IlvN PF07991.12 ORY14067.1 - 0.0029 17.2 0.0 0.0059 16.2 0.0 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain OCD_Mu_crystall PF02423.15 ORY14067.1 - 0.0048 15.9 0.0 0.012 14.6 0.0 1.6 1 1 1 2 2 2 1 Ornithine cyclodeaminase/mu-crystallin family FAD_binding_3 PF01494.19 ORY14068.1 - 2.5e-25 89.5 0.0 3.4e-25 89.0 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 ORY14068.1 - 3.1e-07 30.3 0.0 0.00085 19.0 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ORY14068.1 - 4.2e-07 29.5 0.2 0.012 14.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORY14068.1 - 1.4e-06 28.8 0.5 0.0021 18.6 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORY14068.1 - 5.6e-05 23.3 0.0 0.00014 22.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 ORY14068.1 - 0.0047 15.8 0.3 5.3 5.8 0.0 2.9 2 1 1 3 3 3 2 Tryptophan halogenase ApbA PF02558.16 ORY14068.1 - 0.013 15.2 0.1 0.024 14.3 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Thi4 PF01946.17 ORY14068.1 - 0.037 13.2 0.2 0.1 11.8 0.0 1.7 2 0 0 2 2 2 0 Thi4 family HI0933_like PF03486.14 ORY14068.1 - 0.045 12.5 0.1 11 4.7 0.0 2.8 2 1 0 3 3 3 0 HI0933-like protein FAD_binding_2 PF00890.24 ORY14068.1 - 0.094 11.8 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.22 ORY14068.1 - 0.14 11.2 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Amino_oxidase PF01593.24 ORY14068.1 - 0.18 11.1 0.1 0.79 8.9 0.0 1.9 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase zf-RING_7 PF02591.15 ORY14069.1 - 0.12 12.6 2.6 3.6 7.9 0.1 3.0 3 0 0 3 3 3 0 C4-type zinc ribbon domain Fungal_trans PF04082.18 ORY14073.1 - 1.7e-13 50.2 2.8 2.8e-13 49.5 1.4 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain RRT14 PF17075.5 ORY14075.1 - 0.012 15.7 5.5 0.016 15.3 5.5 1.3 1 0 0 1 1 1 0 Regular of rDNA transcription protein 14 CSRNP_N PF16019.5 ORY14075.1 - 0.089 12.7 6.3 0.1 12.5 6.3 1.2 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus Presenilin PF01080.17 ORY14075.1 - 0.099 11.4 3.2 0.14 10.9 3.2 1.1 1 0 0 1 1 1 0 Presenilin Cas_CT1975 PF09344.10 ORY14075.1 - 0.33 10.4 6.4 0.41 10.1 6.4 1.1 1 0 0 1 1 1 0 CT1975-like protein DUF4338 PF14236.6 ORY14075.1 - 5.7 6.1 10.6 14 4.9 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4338) Aldedh PF00171.22 ORY14076.1 - 3.3e-78 263.3 0.0 4e-78 263.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family TrbM PF07424.11 ORY14078.1 - 0.051 13.5 2.1 3.2 7.7 0.6 2.3 1 1 1 2 2 2 0 TrbM VHL PF01847.16 ORY14079.1 - 0.042 13.8 0.0 0.074 13.0 0.0 1.3 1 0 0 1 1 1 0 VHL beta domain Trehalase PF01204.18 ORY14081.1 - 4.3e-195 649.4 0.0 4.9e-195 649.2 0.0 1.0 1 0 0 1 1 1 1 Trehalase OCRE PF17780.1 ORY14081.1 - 0.092 12.8 0.4 0.27 11.3 0.4 1.9 1 0 0 1 1 1 0 OCRE domain MBF1 PF08523.10 ORY14082.1 - 3.2e-26 91.6 1.0 3.2e-26 91.6 1.0 1.6 2 0 0 2 2 2 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 ORY14082.1 - 2.8e-08 33.7 0.0 5.4e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 ORY14082.1 - 0.023 15.1 0.0 0.066 13.6 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain CDC27 PF09507.10 ORY14083.1 - 0.00021 20.8 17.1 0.00027 20.5 17.1 1.1 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 Ndc1_Nup PF09531.10 ORY14083.1 - 0.52 8.9 3.9 0.62 8.7 3.9 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup V_ATPase_I PF01496.19 ORY14083.1 - 0.96 7.3 7.0 1.5 6.6 7.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CDC45 PF02724.14 ORY14083.1 - 9.3 4.4 15.4 11 4.1 15.4 1.2 1 0 0 1 1 1 0 CDC45-like protein RELT PF12606.8 ORY14086.1 - 0.16 11.0 2.5 0.34 9.9 2.5 1.6 1 0 0 1 1 1 0 Tumour necrosis factor receptor superfamily member 19 Med3 PF11593.8 ORY14086.1 - 0.27 10.4 3.1 0.31 10.2 3.1 1.0 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF4407 PF14362.6 ORY14087.1 - 0.13 11.6 5.5 0.16 11.3 5.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Proteasome PF00227.26 ORY14089.1 - 3.2e-49 167.0 0.1 4.3e-49 166.6 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 ORY14089.1 - 5.1e-13 48.4 0.3 8.3e-13 47.8 0.3 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Amidase_5 PF05382.13 ORY14089.1 - 0.068 13.1 0.0 2.7 7.9 0.0 2.2 2 0 0 2 2 2 0 Bacteriophage peptidoglycan hydrolase DUF2373 PF10180.9 ORY14090.1 - 1.4e-18 66.5 0.0 4.3e-18 64.9 0.0 1.8 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2373) Cellulase PF00150.18 ORY14125.1 - 1.2e-18 67.6 8.6 2.9e-18 66.3 8.6 1.6 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Kelch_3 PF13415.6 ORY14127.1 - 1.8e-31 107.8 8.0 6.2e-08 32.7 0.0 6.2 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_4 PF13418.6 ORY14127.1 - 1.8e-29 101.5 12.7 5.8e-13 48.6 0.0 6.9 6 2 0 6 6 6 5 Galactose oxidase, central domain Kelch_6 PF13964.6 ORY14127.1 - 8.8e-16 57.6 5.9 0.0016 18.7 0.1 6.4 5 1 1 6 6 6 4 Kelch motif Kelch_1 PF01344.25 ORY14127.1 - 1.4e-11 43.8 2.4 0.041 13.5 0.0 5.7 5 0 0 5 5 5 4 Kelch motif Kelch_2 PF07646.15 ORY14127.1 - 6.1e-10 38.7 13.6 0.35 10.9 0.7 6.7 6 1 0 6 6 6 5 Kelch motif Kelch_5 PF13854.6 ORY14127.1 - 5.2e-08 32.7 2.1 1.3 9.1 0.0 5.3 6 1 0 6 6 6 3 Kelch motif DTHCT PF08070.11 ORY14128.1 - 0.00014 22.5 6.4 0.00014 22.5 6.4 4.5 3 1 1 4 4 4 1 DTHCT (NUC029) region Macoilin PF09726.9 ORY14128.1 - 2.2 6.8 14.3 3.7 6.0 14.3 1.4 1 0 0 1 1 1 0 Macoilin family Apt1 PF10351.9 ORY14128.1 - 6.2 5.6 20.9 0.46 9.3 16.3 1.5 2 0 0 2 2 2 0 Golgi-body localisation protein domain DUF3176 PF11374.8 ORY14129.1 - 5.6e-37 126.2 0.8 5.6e-37 126.2 0.8 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) DUF3682 PF12446.8 ORY14129.1 - 0.1 13.1 1.5 0.22 12.0 1.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) Peroxidase_2 PF01328.17 ORY14130.1 - 1.3e-24 87.8 0.1 5.3e-22 79.3 0.1 2.2 2 0 0 2 2 2 2 Peroxidase, family 2 Meth_synt_2 PF01717.18 ORY14131.1 - 5.8e-11 42.2 0.0 8.4e-11 41.7 0.0 1.2 1 0 0 1 1 1 1 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 ORY14131.1 - 0.0072 15.9 0.0 0.028 13.9 0.0 1.9 3 0 0 3 3 3 1 Cobalamin-independent synthase, N-terminal domain DREV PF05219.12 ORY14131.1 - 0.14 11.2 0.0 2.6 7.0 0.0 2.1 2 0 0 2 2 2 0 DREV methyltransferase Carb_bind PF10645.9 ORY14132.1 - 0.1 12.8 0.3 0.24 11.6 0.3 1.5 1 0 0 1 1 1 0 Carbohydrate binding Utp11 PF03998.13 ORY14133.1 - 4.1e-61 207.0 27.7 7.1e-61 206.2 27.7 1.4 1 1 0 1 1 1 1 Utp11 protein adh_short PF00106.25 ORY14134.1 - 1.4e-37 129.1 0.3 1.7e-37 128.8 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY14134.1 - 5.9e-31 107.8 0.2 7.4e-31 107.5 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY14134.1 - 1.1e-07 32.0 2.6 5.1e-07 29.8 2.3 2.1 1 1 0 1 1 1 1 KR domain DUF2232 PF09991.9 ORY14134.1 - 0.081 12.1 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) MG4 PF17789.1 ORY14134.1 - 0.084 13.0 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Macroglobulin domain MG4 UBD PF16455.5 ORY14134.1 - 0.1 12.9 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-binding domain Cmc1 PF08583.10 ORY14135.1 - 8.5e-18 64.1 7.0 2.1e-17 62.9 7.0 1.7 1 1 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like NDUF_B7 PF05676.13 ORY14135.1 - 3.8e-05 23.3 1.6 6.3e-05 22.6 1.6 1.4 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) CHCH PF06747.13 ORY14135.1 - 0.0015 18.6 0.6 0.0065 16.6 0.3 2.0 1 1 1 2 2 2 1 CHCH domain COX17 PF05051.13 ORY14135.1 - 0.0017 18.7 1.5 0.13 12.6 0.2 2.3 2 0 0 2 2 2 2 Cytochrome C oxidase copper chaperone (COX17) CX9C PF16860.5 ORY14135.1 - 0.0066 16.4 1.5 0.011 15.7 1.5 1.4 1 0 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, TFIID-31kDa PF02291.15 ORY14136.1 - 1.8e-45 154.0 0.0 2.4e-45 153.6 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit fn3 PF00041.21 ORY14137.1 - 0.00012 22.4 0.0 0.0061 16.9 0.0 2.6 1 1 0 1 1 1 1 Fibronectin type III domain HSBP1 PF06825.12 ORY14137.1 - 0.82 9.6 4.2 2 8.3 4.2 1.6 1 0 0 1 1 1 0 Heat shock factor binding protein 1 DUF1515 PF07439.11 ORY14137.1 - 7.8 6.6 7.0 3.4 7.7 4.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) LNS2 PF08235.13 ORY14138.1 - 8.7e-93 309.9 0.0 1.4e-92 309.3 0.0 1.3 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 ORY14138.1 - 2.3e-42 143.1 0.0 4.3e-42 142.2 0.0 1.5 1 0 0 1 1 1 1 lipin, N-terminal conserved region Acid_phosphat_B PF03767.14 ORY14138.1 - 0.038 13.6 0.3 0.79 9.3 0.0 2.8 3 0 0 3 3 3 0 HAD superfamily, subfamily IIIB (Acid phosphatase) Thg1 PF04446.12 ORY14139.1 - 2.4e-51 173.0 0.0 3.5e-51 172.4 0.0 1.3 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Thg1C PF14413.6 ORY14139.1 - 7.4e-48 161.7 0.1 3.8e-43 146.5 0.0 2.4 2 0 0 2 2 2 2 Thg1 C terminal domain FAM60A PF15396.6 ORY14139.1 - 0.28 11.2 1.8 0.52 10.3 1.8 1.3 1 0 0 1 1 1 0 Protein Family FAM60A YtzH PF14165.6 ORY14140.1 - 3.3 8.2 7.6 14 6.2 0.3 2.8 2 0 0 2 2 2 0 YtzH-like protein Metallophos PF00149.28 ORY14141.1 - 3.3e-12 47.3 0.3 5.9e-12 46.5 0.3 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase MFS_1 PF07690.16 ORY14142.1 - 0.0023 16.9 35.1 0.043 12.7 31.2 3.5 2 1 0 2 2 2 2 Major Facilitator Superfamily Phage_holin_3_6 PF07332.11 ORY14142.1 - 0.047 13.7 0.0 0.047 13.7 0.0 4.5 4 1 0 5 5 5 0 Putative Actinobacterial Holin-X, holin superfamily III Amidase PF01425.21 ORY14143.1 - 5.5e-111 371.7 0.0 6.5e-111 371.5 0.0 1.0 1 0 0 1 1 1 1 Amidase MFS_1 PF07690.16 ORY14144.1 - 2.1e-34 119.0 24.1 2.1e-34 119.0 24.1 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily MIP PF00230.20 ORY14145.1 - 1.5e-48 165.5 14.9 1.9e-48 165.2 14.9 1.0 1 0 0 1 1 1 1 Major intrinsic protein TPR_12 PF13424.6 ORY14146.1 - 3.7e-34 116.8 6.5 8.3e-10 38.8 0.0 7.1 4 1 3 7 7 7 6 Tetratricopeptide repeat TPR_10 PF13374.6 ORY14146.1 - 1.9e-24 84.8 10.5 0.00013 21.7 0.0 8.2 9 0 0 9 9 8 6 Tetratricopeptide repeat NB-ARC PF00931.22 ORY14146.1 - 1.8e-12 47.0 0.0 3.7e-10 39.4 0.0 3.0 2 1 0 2 2 2 1 NB-ARC domain TPR_2 PF07719.17 ORY14146.1 - 5.6e-08 32.3 1.8 0.98 9.7 0.0 6.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 ORY14146.1 - 4.2e-06 27.1 2.5 0.94 10.5 0.0 5.8 6 1 1 7 7 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 ORY14146.1 - 6.5e-06 26.0 0.0 0.49 10.7 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_MalT PF17874.1 ORY14146.1 - 1.1e-05 25.0 2.2 0.00013 21.5 0.0 3.1 3 1 1 4 4 4 1 MalT-like TPR region TPR_7 PF13176.6 ORY14146.1 - 1.5e-05 24.7 0.4 2.1 8.6 0.0 5.1 6 0 0 6 6 5 2 Tetratricopeptide repeat ATPase_2 PF01637.18 ORY14146.1 - 2.3e-05 24.4 0.0 4.3e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea TPR_16 PF13432.6 ORY14146.1 - 3.1e-05 24.5 0.0 1.1 9.9 0.0 4.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 ORY14146.1 - 4.8e-05 23.8 0.0 2.9 8.5 0.0 4.3 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_4 PF07721.14 ORY14146.1 - 0.00014 22.1 0.7 0.62 10.8 0.0 4.8 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 ORY14146.1 - 0.00026 20.7 0.1 2.3 8.2 0.0 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat AAA_16 PF13191.6 ORY14146.1 - 0.0032 17.9 0.1 0.018 15.4 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain TPR_20 PF14561.6 ORY14146.1 - 0.0053 17.1 0.0 2.4 8.5 0.0 3.9 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 ORY14146.1 - 0.0066 16.7 0.0 1.7 9.2 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 ORY14146.1 - 0.017 15.7 0.4 1.9 9.3 0.0 3.8 3 0 0 3 3 2 0 Tetratricopeptide repeat PPR PF01535.20 ORY14146.1 - 0.053 13.8 0.0 12 6.4 0.0 3.3 2 0 0 2 2 2 0 PPR repeat p450 PF00067.22 ORY14147.1 - 8.8e-65 219.2 0.0 1.1e-64 218.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 LCM PF04072.14 ORY14147.1 - 0.11 12.5 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Leucine carboxyl methyltransferase DUF676 PF05057.14 ORY14148.1 - 1.4e-05 24.7 0.2 2.8e-05 23.7 0.2 1.4 1 1 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 ORY14148.1 - 0.00019 21.2 0.1 0.00027 20.7 0.1 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 ORY14148.1 - 0.005 17.5 0.0 0.0057 17.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Palm_thioest PF02089.15 ORY14148.1 - 0.035 13.9 0.0 0.046 13.6 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Hydrolase_4 PF12146.8 ORY14148.1 - 0.052 12.8 0.5 0.1 11.9 0.0 1.8 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_8 PF06259.12 ORY14148.1 - 0.086 12.5 0.1 0.18 11.4 0.1 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase adh_short_C2 PF13561.6 ORY14149.1 - 4.9e-56 189.9 0.0 6.1e-56 189.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY14149.1 - 2.1e-42 144.8 0.0 2.5e-42 144.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORY14149.1 - 4.3e-10 39.8 0.1 5.9e-10 39.3 0.1 1.2 1 0 0 1 1 1 1 KR domain KRE1 PF17056.5 ORY14149.1 - 0.11 12.2 1.1 0.29 10.9 1.1 1.7 1 0 0 1 1 1 0 Killer toxin-resistance protein 1 DEAD PF00270.29 ORY14150.1 - 8.7e-28 97.3 0.1 2.8e-17 63.1 0.1 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY14150.1 - 3.5e-23 82.1 0.0 2.7e-22 79.2 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY14150.1 - 3.5e-07 30.4 0.3 2.7e-06 27.5 0.0 2.3 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 ORY14150.1 - 0.00094 18.1 0.0 0.0058 15.5 0.0 1.9 2 0 0 2 2 2 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 ATP-synt_G PF04718.15 ORY14151.1 - 7e-35 119.9 0.1 3.6e-34 117.6 0.0 1.9 2 0 0 2 2 2 1 Mitochondrial ATP synthase g subunit Collagen_mid PF15984.5 ORY14151.1 - 0.00073 19.3 0.9 0.001 18.9 0.9 1.3 1 0 0 1 1 1 1 Bacterial collagen, middle region Phage_holin_2_1 PF04971.12 ORY14151.1 - 0.015 15.3 0.0 0.041 13.9 0.0 1.7 1 0 0 1 1 1 0 Bacteriophage P21 holin S Kisspeptin PF15152.6 ORY14151.1 - 0.4 11.5 1.5 1.4 9.8 0.0 2.1 2 0 0 2 2 2 0 Kisspeptin Pyr_redox_2 PF07992.14 ORY14152.1 - 4.7e-55 186.9 0.0 1.2e-54 185.6 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 ORY14152.1 - 1.4e-33 115.5 3.0 2.7e-32 111.3 0.5 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 ORY14152.1 - 1.4e-13 51.2 2.5 2.8e-13 50.2 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ORY14152.1 - 3.7e-09 36.3 0.1 1e-05 24.9 0.0 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ORY14152.1 - 5.2e-05 22.5 0.0 0.00016 20.9 0.0 1.7 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_oxidored PF12831.7 ORY14152.1 - 0.00023 20.7 0.1 0.0003 20.3 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 ORY14152.1 - 0.00044 19.5 0.1 0.0021 17.2 0.0 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.14 ORY14152.1 - 0.049 12.3 0.3 1.5 7.5 0.6 2.6 3 0 0 3 3 3 0 HI0933-like protein Peptidase_M16 PF00675.20 ORY14152.1 - 0.095 12.7 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Insulinase (Peptidase family M16) 2-Hacid_dh_C PF02826.19 ORY14152.1 - 0.19 11.1 0.8 0.57 9.5 0.1 2.1 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 ORY14152.1 - 2.9 6.9 6.3 0.71 8.9 2.0 2.1 3 0 0 3 3 3 0 FAD binding domain 3HCDH_N PF02737.18 ORY14152.1 - 4.9 7.0 6.2 0.41 10.5 0.2 2.2 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Glyco_tranf_2_3 PF13641.6 ORY14153.1 - 6.3e-33 114.6 0.0 9.5e-33 114.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 ORY14153.1 - 8.8e-12 45.2 0.0 1.6e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.6 ORY14153.1 - 1.6e-09 37.9 3.0 4.9e-09 36.4 3.0 1.9 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 ORY14153.1 - 8.5e-08 31.9 0.0 7.3e-07 28.8 0.0 2.0 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glyco_transf_64 PF09258.10 ORY14153.1 - 0.04 13.2 0.0 0.055 12.7 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 64 domain NYN PF01936.18 ORY14153.1 - 0.13 12.8 0.0 0.25 11.8 0.0 1.4 1 0 0 1 1 1 0 NYN domain Amidohydro_2 PF04909.14 ORY14155.1 - 1.1e-13 51.7 0.2 7.6e-13 48.9 0.0 2.0 2 0 0 2 2 2 1 Amidohydrolase Clr5 PF14420.6 ORY14156.1 - 2.6e-05 24.3 0.0 8.9e-05 22.6 0.0 1.9 1 0 0 1 1 1 1 Clr5 domain Spt5_N PF11942.8 ORY14156.1 - 0.03 15.3 5.1 0.41 11.7 1.5 2.6 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal HATPase_c PF02518.26 ORY14157.1 - 1.1e-23 83.9 0.1 3.4e-23 82.3 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 ORY14157.1 - 8.5e-22 77.4 0.0 2.1e-21 76.2 0.0 1.8 1 0 0 1 1 1 1 Response regulator receiver domain PAS_4 PF08448.10 ORY14157.1 - 3.9e-09 36.7 0.0 1.5e-07 31.6 0.0 2.8 2 0 0 2 2 2 1 PAS fold PAS PF00989.25 ORY14157.1 - 1.2e-07 31.7 0.1 1.4e-05 25.0 0.0 3.3 4 0 0 4 4 4 1 PAS fold PAS_9 PF13426.7 ORY14157.1 - 2.7e-07 30.8 0.0 6.5e-06 26.4 0.0 3.0 2 1 1 3 3 3 1 PAS domain PAS_8 PF13188.7 ORY14157.1 - 3.5e-07 30.1 0.0 1.2e-06 28.4 0.0 2.0 1 0 0 1 1 1 1 PAS domain HisKA PF00512.25 ORY14157.1 - 6.6e-07 29.3 0.2 6.6e-07 29.3 0.2 2.4 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.12 ORY14157.1 - 0.00058 20.1 0.1 0.0014 18.8 0.1 1.7 1 0 0 1 1 1 1 PAS fold HATPase_c_3 PF13589.6 ORY14157.1 - 0.026 14.4 0.4 0.26 11.1 0.0 2.5 2 1 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GAF_3 PF13492.6 ORY14157.1 - 0.14 12.5 0.0 0.39 11.1 0.0 1.8 1 0 0 1 1 1 0 GAF domain WW PF00397.26 ORY14159.1 - 1.5e-10 41.0 3.5 2.9e-10 40.0 3.5 1.5 1 0 0 1 1 1 1 WW domain PmrD PF11183.8 ORY14160.1 - 0.24 11.5 0.1 1.3 9.2 0.0 2.0 2 0 0 2 2 2 0 Polymyxin resistance protein PmrD UDG PF03167.19 ORY14161.1 - 3.1e-17 63.0 0.0 5.6e-17 62.1 0.0 1.4 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Glyco_hydro_45 PF02015.16 ORY14162.1 - 2.7e-80 269.2 19.4 3.3e-80 269.0 19.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 CssAB PF16831.5 ORY14162.1 - 0.026 14.9 0.1 0.047 14.1 0.1 1.4 1 0 0 1 1 1 0 CS6 fimbrial subunits A and B, Coli surface antigen 6 AAA_33 PF13671.6 ORY14162.1 - 0.19 11.9 0.3 0.51 10.5 0.3 1.8 1 1 0 1 1 1 0 AAA domain FAD_binding_4 PF01565.23 ORY14164.1 - 1.9e-06 27.7 1.1 1e-05 25.3 1.4 1.9 2 0 0 2 2 2 1 FAD binding domain FAD_binding_4 PF01565.23 ORY14165.1 - 3e-05 23.8 0.0 3.7e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Fringe PF02434.16 ORY14167.1 - 5.5e-09 35.8 0.2 9.4e-08 31.8 0.4 2.3 2 1 0 2 2 2 1 Fringe-like Galactosyl_T PF01762.21 ORY14167.1 - 0.00033 20.5 0.1 0.01 15.6 0.1 2.2 1 1 1 2 2 2 1 Galactosyltransferase PAN_4 PF14295.6 ORY14167.1 - 0.017 15.0 1.2 0.039 13.8 1.2 1.6 1 0 0 1 1 1 0 PAN domain Glyco_transf_34 PF05637.12 ORY14167.1 - 0.1 12.3 1.4 0.17 11.6 1.4 1.3 1 0 0 1 1 1 0 galactosyl transferase GMA12/MNN10 family SH3_9 PF14604.6 ORY14169.1 - 8.6e-14 51.1 0.1 1.6e-13 50.3 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 ORY14169.1 - 1.8e-11 43.5 0.0 3.5e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SAM_2 PF07647.17 ORY14169.1 - 4.1e-10 39.6 0.0 6.8e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH PF00169.29 ORY14169.1 - 6.6e-09 36.2 0.0 5e-08 33.4 0.0 2.4 1 1 0 1 1 1 1 PH domain SH3_2 PF07653.17 ORY14169.1 - 1.2e-05 24.9 0.0 2.4e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SAM_1 PF00536.30 ORY14169.1 - 0.00018 21.9 0.0 0.00031 21.1 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 ORY14169.1 - 0.074 13.0 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain zf-MIZ PF02891.20 ORY14170.1 - 9.8e-12 44.4 0.7 2.1e-11 43.4 0.7 1.6 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger Rubredoxin PF00301.20 ORY14170.1 - 0.54 10.3 2.0 1.2 9.2 2.0 1.5 1 0 0 1 1 1 0 Rubredoxin SAS4 PF15460.6 ORY14171.1 - 0.0015 18.6 2.5 0.0025 17.9 2.5 1.3 1 0 0 1 1 1 1 Something about silencing, SAS, complex subunit 4 FAM184 PF15665.5 ORY14171.1 - 0.029 14.2 1.7 0.039 13.7 0.8 1.7 1 1 0 1 1 1 0 Family with sequence similarity 184, A and B DUF2205 PF10224.9 ORY14176.1 - 3.8e-33 113.3 0.5 6.2e-33 112.6 0.5 1.3 1 0 0 1 1 1 1 Short coiled-coil protein CybS PF05328.12 ORY14177.1 - 8.2e-54 180.9 0.0 1.1e-53 180.5 0.0 1.2 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit Peptidase_M16 PF00675.20 ORY14178.1 - 4.1e-57 192.3 0.1 9.1e-57 191.2 0.1 1.6 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 ORY14178.1 - 2e-32 112.7 0.0 1.9e-31 109.5 0.0 2.3 2 0 0 2 2 2 1 Peptidase M16 inactive domain 14-3-3 PF00244.20 ORY14179.1 - 1.9e-106 354.5 5.5 2.3e-106 354.3 5.5 1.0 1 0 0 1 1 1 1 14-3-3 protein TPR_12 PF13424.6 ORY14179.1 - 0.0028 17.9 1.0 0.39 11.0 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TerB PF05099.13 ORY14179.1 - 0.021 14.8 1.2 0.041 13.8 0.3 1.9 2 0 0 2 2 2 0 Tellurite resistance protein TerB Orbi_VP5 PF00901.17 ORY14179.1 - 0.17 10.2 3.8 0.3 9.4 3.8 1.3 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 IATP PF04568.12 ORY14180.1 - 6.5e-23 81.0 1.7 7.3e-23 80.9 1.7 1.0 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP Stathmin PF00836.19 ORY14180.1 - 0.003 17.5 4.5 0.0047 16.9 4.5 1.3 1 0 0 1 1 1 1 Stathmin family DUF5339 PF17274.2 ORY14180.1 - 0.016 16.1 1.8 0.023 15.6 1.8 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5339) DUF730 PF05325.11 ORY14180.1 - 0.033 14.2 0.0 0.039 14.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF730) DUF4268 PF14088.6 ORY14180.1 - 0.057 13.3 1.3 0.074 12.9 1.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4268) FlaC_arch PF05377.11 ORY14180.1 - 0.13 12.7 1.7 0.19 12.2 1.7 1.2 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) Nsp1_C PF05064.13 ORY14181.1 - 6.6e-40 135.5 0.7 6.6e-40 135.5 0.7 2.2 2 1 0 2 2 2 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.6 ORY14181.1 - 0.00027 21.7 28.3 0.00027 21.7 28.3 6.2 1 1 4 5 5 2 1 Nucleoporin FG repeat region DUF4200 PF13863.6 ORY14181.1 - 0.0032 17.8 13.6 0.34 11.3 0.1 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4200) ATG16 PF08614.11 ORY14181.1 - 0.0042 17.4 8.8 0.031 14.5 0.2 3.0 2 1 0 2 2 2 1 Autophagy protein 16 (ATG16) DUF812 PF05667.11 ORY14181.1 - 0.011 14.7 3.3 0.045 12.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF812) BRE1 PF08647.11 ORY14181.1 - 0.011 15.8 15.4 0.3 11.2 5.6 2.2 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase Peptidase_S64 PF08192.11 ORY14181.1 - 0.014 13.9 0.7 0.027 13.0 0.7 1.4 1 0 0 1 1 1 0 Peptidase family S64 EH_Signature PF15611.6 ORY14181.1 - 0.023 14.1 1.2 0.033 13.6 1.2 1.1 1 0 0 1 1 1 0 EH_Signature domain DUF3450 PF11932.8 ORY14181.1 - 0.17 11.2 0.1 0.17 11.2 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) PI_PP_I PF18363.1 ORY14181.1 - 0.36 11.0 4.7 0.14 12.3 1.7 1.8 2 0 0 2 2 2 0 Phosphoinositide phosphatase insertion domain FAM76 PF16046.5 ORY14181.1 - 0.39 10.0 2.9 1 8.7 0.1 2.2 2 0 0 2 2 2 0 FAM76 protein DUF1664 PF07889.12 ORY14181.1 - 0.44 10.6 7.3 2.7 8.1 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Phage_GPO PF05929.11 ORY14181.1 - 0.45 10.1 4.8 0.95 9.0 0.5 2.2 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Dynamitin PF04912.14 ORY14181.1 - 0.53 9.6 13.3 0.07 12.5 2.4 2.7 2 1 0 3 3 3 0 Dynamitin FlaC_arch PF05377.11 ORY14181.1 - 0.71 10.3 6.1 29 5.1 0.0 3.3 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) ERM PF00769.19 ORY14181.1 - 0.96 9.2 15.1 3.1 7.5 15.1 1.8 1 1 0 1 1 1 0 Ezrin/radixin/moesin family OmpH PF03938.14 ORY14181.1 - 1.1 9.6 18.5 2.6 8.4 6.1 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Laminin_II PF06009.12 ORY14181.1 - 2.4 8.2 12.0 1.6 8.7 2.2 2.8 2 1 1 3 3 3 0 Laminin Domain II WXG100 PF06013.12 ORY14181.1 - 4.9 7.4 10.9 13 6.1 0.1 3.8 4 0 0 4 4 3 0 Proteins of 100 residues with WXG EzrA PF06160.12 ORY14181.1 - 5 5.2 15.6 0.4 8.8 1.9 2.0 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA HOOK PF05622.12 ORY14181.1 - 5.4 5.0 16.2 0.62 8.1 6.0 2.0 2 0 0 2 2 2 0 HOOK protein DUF948 PF06103.11 ORY14181.1 - 8.3 6.7 5.2 3.6 7.9 0.6 2.4 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF4201 PF13870.6 ORY14181.1 - 9.1 6.0 12.0 0.57 9.9 0.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) Taxilin PF09728.9 ORY14181.1 - 9.2 5.3 14.2 0.18 10.9 0.8 2.2 2 0 0 2 2 2 0 Myosin-like coiled-coil protein DUF5102 PF17104.5 ORY14182.1 - 1.3e-106 356.9 0.9 2.9e-106 355.7 0.9 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5102) Caskin-Pro-rich PF16907.5 ORY14182.1 - 0.043 14.3 0.8 0.043 14.3 0.8 2.8 3 0 0 3 3 3 0 Proline rich region of Caskin proteins Urocanase PF01175.18 ORY14182.1 - 0.099 12.3 0.0 0.42 10.2 0.0 1.8 2 0 0 2 2 2 0 Urocanase Rossmann-like domain PRIMA1 PF16101.5 ORY14182.1 - 2.8 8.0 7.6 1.1 9.3 0.5 2.8 3 0 0 3 3 3 0 Proline-rich membrane anchor 1 HAMP PF00672.25 ORY14183.1 - 1.9e-35 121.0 22.9 8.6e-08 32.5 0.4 7.9 6 1 1 7 7 7 6 HAMP domain HATPase_c PF02518.26 ORY14183.1 - 2e-30 105.6 0.1 7.8e-30 103.7 0.1 2.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 ORY14183.1 - 3.2e-27 94.9 0.1 1.7e-26 92.6 0.2 2.3 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 ORY14183.1 - 2.3e-16 59.6 0.5 2.3e-16 59.6 0.5 4.1 5 0 0 5 5 4 1 His Kinase A (phospho-acceptor) domain Syntaxin_2 PF14523.6 ORY14183.1 - 1.3e-09 38.4 13.9 1.6 9.2 0.1 7.8 5 2 3 8 8 8 3 Syntaxin-like protein DUF4279 PF14106.6 ORY14183.1 - 1.6e-05 25.1 1.2 29 4.9 0.0 6.1 6 0 0 6 6 6 0 Domain of unknown function (DUF4279) Laminin_II PF06009.12 ORY14183.1 - 0.00019 21.4 37.8 0.4 10.7 1.6 7.5 8 0 0 8 8 7 4 Laminin Domain II DUF948 PF06103.11 ORY14183.1 - 0.0081 16.4 54.4 0.27 11.5 2.4 10.5 4 2 5 9 9 9 2 Bacterial protein of unknown function (DUF948) DUF3829 PF12889.7 ORY14183.1 - 0.0093 15.5 13.2 0.14 11.6 0.0 5.1 2 2 5 7 7 7 1 Protein of unknown function (DUF3829) Phage_Gp23 PF10669.9 ORY14183.1 - 0.065 13.6 0.4 0.22 11.9 0.4 1.9 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) SpoIIID PF12116.8 ORY14183.1 - 0.074 13.2 1.3 9.8 6.4 0.0 4.2 4 0 0 4 4 3 0 Stage III sporulation protein D AdHead_fibreRBD PF16812.5 ORY14183.1 - 0.089 12.6 0.8 0.36 10.6 0.1 2.3 3 0 0 3 3 2 0 C-terminal head domain of the fowl adenovirus type 1 long fibre GLE1 PF07817.13 ORY14183.1 - 0.17 11.1 16.7 4.9 6.3 0.0 5.7 3 1 3 6 6 6 0 GLE1-like protein HSBP1 PF06825.12 ORY14183.1 - 0.18 11.7 3.3 1 9.3 0.4 3.6 2 0 0 2 2 2 0 Heat shock factor binding protein 1 Atg14 PF10186.9 ORY14183.1 - 0.22 10.6 4.2 0.51 9.4 1.1 2.6 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Fib_alpha PF08702.10 ORY14183.1 - 3 8.0 32.7 6.1 7.0 0.1 7.1 6 1 0 7 7 7 0 Fibrinogen alpha/beta chain family DUF4763 PF15960.5 ORY14183.1 - 4.8 6.4 8.5 6.9 5.9 0.0 4.4 5 0 0 5 5 5 0 Domain of unknown function (DUF4763) CMD PF02627.20 ORY14183.1 - 8.1 6.6 9.4 17 5.5 0.0 5.3 7 0 0 7 7 6 0 Carboxymuconolactone decarboxylase family DUF1759 PF03564.15 ORY14183.1 - 9.5 6.1 8.1 25 4.8 0.0 4.6 6 0 0 6 6 5 0 Protein of unknown function (DUF1759) SNF2_N PF00176.23 ORY14184.1 - 7.7e-63 212.3 0.0 1.3e-62 211.6 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ORY14184.1 - 4.2e-17 62.5 0.0 8.2e-17 61.6 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.6 ORY14184.1 - 4.6e-09 36.0 2.7 1.2e-08 34.7 2.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 ORY14184.1 - 6e-08 32.4 2.7 6e-08 32.4 2.7 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORY14184.1 - 1.1e-07 31.7 3.6 3.4e-07 30.2 3.6 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 ORY14184.1 - 1.6e-06 28.0 5.4 3.5e-06 26.9 5.4 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 ORY14184.1 - 1.7e-06 27.8 5.6 4.5e-06 26.4 5.6 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORY14184.1 - 1.8e-06 28.2 5.8 5.3e-06 26.7 5.8 1.9 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 ORY14184.1 - 0.00032 20.8 4.8 0.0018 18.4 5.2 2.1 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING ResIII PF04851.15 ORY14184.1 - 0.00034 20.7 0.0 0.0016 18.5 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Prok-RING_4 PF14447.6 ORY14184.1 - 0.02 14.7 7.2 0.15 12.0 7.4 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Pellino PF04710.14 ORY14184.1 - 0.086 11.5 0.4 0.14 10.8 0.4 1.2 1 0 0 1 1 1 0 Pellino zf-RING_4 PF14570.6 ORY14184.1 - 0.088 12.6 5.3 0.32 10.8 5.5 1.9 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain BDHCT_assoc PF16204.5 ORY14184.1 - 0.55 9.9 4.2 1 9.0 4.2 1.3 1 0 0 1 1 1 0 BDHCT-box associated domain on Bloom syndrome protein YL1 PF05764.13 ORY14184.1 - 1.5 8.9 17.5 3.1 7.8 17.5 1.4 1 0 0 1 1 1 0 YL1 nuclear protein CDC45 PF02724.14 ORY14184.1 - 4.1 5.6 11.9 6.6 4.9 11.9 1.2 1 0 0 1 1 1 0 CDC45-like protein CENP-B_dimeris PF09026.10 ORY14184.1 - 8.8 6.8 15.0 20 5.6 15.0 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain CTNNBL PF08216.11 ORY14185.1 - 4.5e-36 123.2 0.9 4.5e-36 123.2 0.9 1.9 2 0 0 2 2 2 1 Catenin-beta-like, Arm-motif containing nuclear Mo25 PF08569.11 ORY14185.1 - 0.0041 16.5 0.5 0.028 13.8 0.2 2.1 1 1 1 2 2 2 1 Mo25-like Ank_2 PF12796.7 ORY14188.1 - 6.9e-86 282.9 27.3 9.2e-13 48.6 0.0 10.6 2 2 11 13 13 13 13 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ORY14188.1 - 1.5e-59 197.2 16.8 2.2e-08 34.2 0.0 14.1 7 5 6 14 14 14 13 Ankyrin repeats (many copies) Ank PF00023.30 ORY14188.1 - 1.3e-58 193.0 30.1 7.8e-06 26.1 0.0 18.7 19 0 0 19 19 19 13 Ankyrin repeat Ank_3 PF13606.6 ORY14188.1 - 1.6e-54 175.4 9.4 0.00046 20.4 0.0 18.1 19 0 0 19 19 19 13 Ankyrin repeat Ank_4 PF13637.6 ORY14188.1 - 2.1e-50 168.5 16.0 2.7e-08 34.2 0.0 14.6 8 5 10 18 18 18 11 Ankyrin repeats (many copies) MFS_1 PF07690.16 ORY14189.1 - 2.3e-31 109.0 62.3 1.7e-28 99.6 41.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY14189.1 - 1.4e-05 24.2 37.4 8.3e-05 21.6 8.5 3.1 3 0 0 3 3 3 3 Sugar (and other) transporter ADC PF06314.11 ORY14191.1 - 0.00026 20.6 0.2 0.00037 20.1 0.2 1.1 1 0 0 1 1 1 1 Acetoacetate decarboxylase (ADC) zf-C2H2_aberr PF17017.5 ORY14192.1 - 0.00022 21.4 2.9 0.079 13.1 0.3 2.4 2 0 0 2 2 2 2 Aberrant zinc-finger zf-C2H2 PF00096.26 ORY14192.1 - 0.0003 21.1 12.2 0.043 14.3 1.0 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY14192.1 - 0.00038 21.1 11.8 0.033 15.0 0.4 3.8 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORY14192.1 - 0.024 15.1 0.3 0.024 15.1 0.3 3.2 3 0 0 3 3 3 0 Zinc-finger double domain DUF4719 PF15843.5 ORY14192.1 - 0.061 13.4 0.3 0.67 10.0 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4719) Lipocalin_3 PF12702.7 ORY14192.1 - 0.16 12.1 0.0 0.39 10.8 0.0 1.6 1 0 0 1 1 1 0 Lipocalin-like zf-C2H2_jaz PF12171.8 ORY14192.1 - 0.63 10.4 5.1 3.2 8.2 0.0 2.9 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 ORY14192.1 - 3.1 8.2 6.7 2.5 8.5 0.2 2.8 3 0 0 3 3 3 0 C2H2 type zinc-finger (2 copies) Dus PF01207.17 ORY14193.1 - 1e-36 126.7 0.0 2.2e-26 92.7 0.0 2.8 1 1 1 2 2 2 2 Dihydrouridine synthase (Dus) zf_CCCH_4 PF18345.1 ORY14193.1 - 0.0036 17.3 7.7 0.68 10.1 1.9 2.9 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH PF00642.24 ORY14193.1 - 0.066 13.2 4.9 1.5 8.8 0.2 2.7 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 ORY14193.1 - 0.092 12.6 11.2 0.064 13.1 0.6 3.3 3 0 0 3 3 3 0 CCCH-type zinc finger Bap31 PF05529.12 ORY14194.1 - 9e-46 155.1 4.5 1.2e-45 154.6 4.5 1.2 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region Bap31_Bap29_C PF18035.1 ORY14194.1 - 2.9e-11 43.2 0.9 4.4e-11 42.6 0.1 1.7 2 0 0 2 2 2 1 Bap31/Bap29 cytoplasmic coiled-coil domain Cast PF10174.9 ORY14194.1 - 0.0036 15.6 0.2 0.0045 15.3 0.2 1.0 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone DivIC PF04977.15 ORY14194.1 - 0.0039 16.9 4.1 0.067 13.0 0.7 3.5 4 0 0 4 4 4 1 Septum formation initiator Lebercilin PF15619.6 ORY14194.1 - 0.0049 16.6 0.3 0.0073 16.0 0.3 1.3 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease Spc7 PF08317.11 ORY14194.1 - 0.03 13.2 0.4 0.043 12.7 0.4 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Csm1_N PF18504.1 ORY14194.1 - 0.069 13.5 0.6 0.15 12.4 0.1 1.7 2 0 0 2 2 2 0 Csm1 N-terminal domain TolA_bind_tri PF16331.5 ORY14194.1 - 0.16 12.0 3.5 0.17 12.0 0.5 2.3 3 0 0 3 3 3 0 TolA binding protein trimerisation Amidase PF01425.21 ORY14195.1 - 8.7e-61 206.2 0.0 3.5e-58 197.7 0.0 3.0 1 1 0 1 1 1 1 Amidase His_Phos_2 PF00328.22 ORY14196.1 - 3.3e-39 135.3 0.0 4e-39 135.1 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RTA1 PF04479.13 ORY14197.1 - 1.6e-55 187.9 15.2 2.2e-55 187.5 15.2 1.2 1 0 0 1 1 1 1 RTA1 like protein PRIMA1 PF16101.5 ORY14199.1 - 0.051 13.6 0.8 0.58 10.2 0.0 2.4 1 1 1 2 2 2 0 Proline-rich membrane anchor 1 Glyco_hydro_61 PF03443.14 ORY14200.1 - 2.5e-41 141.9 0.0 2.8e-41 141.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Esterase_phd PF10503.9 ORY14201.1 - 2.2e-21 76.4 0.3 3.1e-21 75.9 0.3 1.1 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 ORY14201.1 - 1.8e-05 24.3 0.3 2.8e-05 23.7 0.3 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 ORY14201.1 - 0.0027 17.6 0.1 0.0038 17.1 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 ORY14201.1 - 0.0029 17.3 2.5 0.0048 16.6 2.1 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 ORY14201.1 - 0.0059 16.4 0.1 0.012 15.4 0.1 1.5 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Esterase PF00756.20 ORY14201.1 - 0.009 15.7 0.6 0.014 15.0 0.6 1.3 1 0 0 1 1 1 1 Putative esterase Eno-Rase_NADH_b PF12242.8 ORY14201.1 - 0.092 12.5 0.1 0.18 11.5 0.1 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase FA_synthesis PF02504.15 ORY14201.1 - 0.1 11.7 0.1 7 5.6 0.0 2.2 2 0 0 2 2 2 0 Fatty acid synthesis protein BAAT_C PF08840.11 ORY14201.1 - 0.1 12.5 0.3 0.21 11.5 0.3 1.5 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal HET PF06985.11 ORY14202.1 - 5.1e-29 101.5 0.1 8.7e-29 100.7 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF4841 PF16129.5 ORY14203.1 - 0.086 13.1 0.0 3.1 8.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4841) His_binding PF02098.16 ORY14203.1 - 0.11 12.5 0.0 0.19 11.7 0.0 1.5 1 1 0 1 1 1 0 Tick histamine binding protein Response_reg PF00072.24 ORY14205.1 - 2.6e-25 88.7 0.1 5.5e-25 87.7 0.1 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 ORY14205.1 - 3.6e-25 88.7 0.0 4.4e-24 85.1 0.0 2.4 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 ORY14205.1 - 2.3e-13 50.0 0.0 6.1e-13 48.6 0.0 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 ORY14205.1 - 0.00011 22.5 0.3 0.72 10.3 0.0 2.8 2 0 0 2 2 2 2 HAMP domain TBCC_N PF16752.5 ORY14205.1 - 0.042 14.3 1.3 1.4 9.3 0.0 2.6 2 0 0 2 2 2 0 Tubulin-specific chaperone C N-terminal domain EMP70 PF02990.16 ORY14206.1 - 2e-197 657.0 0.3 2.4e-197 656.8 0.3 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 Kelch_4 PF13418.6 ORY14207.1 - 6e-27 93.4 7.8 1.5e-07 31.3 0.0 5.2 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.6 ORY14207.1 - 2.2e-25 88.1 0.3 4.6e-06 26.5 0.0 4.7 4 0 0 4 4 4 4 Kelch motif Kelch_6 PF13964.6 ORY14207.1 - 3.1e-24 84.4 8.2 3.8e-07 30.2 0.3 5.8 5 1 1 6 6 6 4 Kelch motif Kelch_1 PF01344.25 ORY14207.1 - 6.6e-22 76.8 0.3 2e-06 27.3 0.1 5.6 5 0 0 5 5 5 4 Kelch motif Kelch_3 PF13415.6 ORY14207.1 - 3e-20 72.0 8.2 1.4e-07 31.6 0.0 6.3 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_2 PF07646.15 ORY14207.1 - 5.5e-16 57.8 2.5 0.00012 21.9 0.2 4.7 4 0 0 4 4 4 4 Kelch motif BTB PF00651.31 ORY14207.1 - 1.9e-09 37.7 0.0 3.7e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain ANAPC4_WD40 PF12894.7 ORY14208.1 - 5.1e-18 65.2 3.9 4.4e-06 26.9 0.1 4.3 3 1 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 ORY14208.1 - 5.4e-15 55.5 16.5 0.00086 20.1 0.1 6.5 7 0 0 7 7 7 5 WD domain, G-beta repeat Ge1_WD40 PF16529.5 ORY14208.1 - 4.9e-06 25.7 0.1 0.00032 19.8 0.0 3.2 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 ORY14208.1 - 8e-05 22.6 0.8 0.0083 16.0 0.1 2.9 2 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A Glyco_hyd_101C PF17451.2 ORY14208.1 - 0.04 14.2 0.1 1.3 9.3 0.2 2.5 2 0 0 2 2 2 0 Glycosyl hydrolase 101 beta sandwich domain DUF4428 PF14471.6 ORY14209.1 - 0.048 13.6 0.3 11 6.1 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4428) ZZ PF00569.17 ORY14209.1 - 7.6 6.4 7.1 1.8 8.5 0.3 2.8 3 0 0 3 3 3 0 Zinc finger, ZZ type Herpes_glycop_H PF02489.16 ORY14210.1 - 0.05 12.1 0.1 0.1 11.1 0.1 1.4 1 1 0 1 1 1 0 Herpesvirus glycoprotein H main domain Fer4_13 PF13370.6 ORY14210.1 - 1.3 9.6 4.2 46 4.7 0.0 4.2 3 2 1 4 4 4 0 4Fe-4S single cluster domain of Ferredoxin I HemX PF04375.14 ORY14211.1 - 0.019 14.3 0.0 0.026 13.8 0.0 1.1 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase PAN_4 PF14295.6 ORY14211.1 - 0.025 14.5 1.9 1.8 8.5 0.1 2.5 2 0 0 2 2 2 0 PAN domain Tubulin PF00091.25 ORY14211.1 - 0.084 13.1 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 Tubulin/FtsZ family, GTPase domain N_methyl PF07963.12 ORY14211.1 - 1.6 8.4 5.8 2.7 7.7 5.8 1.3 1 0 0 1 1 1 0 Prokaryotic N-terminal methylation motif NPR2 PF06218.11 ORY14212.1 - 8.7e-163 542.1 0.0 1.9e-162 541.0 0.0 1.6 1 1 0 1 1 1 1 Nitrogen permease regulator 2 NPR3 PF03666.13 ORY14212.1 - 0.037 12.8 10.1 1.7 7.4 0.0 3.7 4 0 0 4 4 4 0 Nitrogen Permease regulator of amino acid transport activity 3 Zip PF02535.22 ORY14212.1 - 1 8.5 8.6 1.8 7.7 8.6 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter SelP_N PF04592.14 ORY14212.1 - 4.2 6.7 11.8 7.8 5.8 11.8 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region FYVE PF01363.21 ORY14214.1 - 0.067 13.3 3.0 0.16 12.1 3.0 1.6 1 1 0 1 1 1 0 FYVE zinc finger FPN1 PF06963.12 ORY14215.1 - 2.7e-118 395.3 12.6 3.2e-118 395.1 12.6 1.0 1 0 0 1 1 1 1 Ferroportin1 (FPN1) DUF1286 PF06939.11 ORY14215.1 - 0.1 12.9 0.1 0.1 12.9 0.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1286) APH PF01636.23 ORY14217.1 - 3e-15 56.8 0.0 6e-15 55.8 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 ORY14217.1 - 0.0031 17.1 0.0 0.0047 16.5 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Haspin_kinase PF12330.8 ORY14217.1 - 0.16 10.9 0.0 0.24 10.3 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Methyltransf_2 PF00891.18 ORY14243.1 - 5e-31 107.6 0.0 8.7e-31 106.8 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain MTS PF05175.14 ORY14243.1 - 0.011 15.3 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_16 PF10294.9 ORY14243.1 - 0.039 13.7 0.0 0.12 12.1 0.0 1.7 2 0 0 2 2 2 0 Lysine methyltransferase CheR PF01739.18 ORY14243.1 - 0.048 13.1 0.0 0.13 11.7 0.0 1.6 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain Methyltransf_25 PF13649.6 ORY14243.1 - 0.1 13.3 0.0 0.24 12.1 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Oxidored_FMN PF00724.20 ORY14244.1 - 2.8e-99 332.6 0.0 3.3e-99 332.4 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family AP_endonuc_2 PF01261.24 ORY14244.1 - 0.022 14.2 0.0 7.8 5.9 0.0 2.4 2 1 1 3 3 3 0 Xylose isomerase-like TIM barrel Asp PF00026.23 ORY14245.1 - 3.1e-08 33.4 0.0 0.00028 20.4 0.0 2.2 2 0 0 2 2 2 2 Eukaryotic aspartyl protease COX14 PF14880.6 ORY14245.1 - 0.00036 20.3 0.0 0.00064 19.5 0.0 1.3 1 0 0 1 1 1 1 Cytochrome oxidase c assembly EphA2_TM PF14575.6 ORY14245.1 - 0.053 14.4 0.0 0.098 13.5 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain m04gp34like PF12216.8 ORY14245.1 - 0.065 12.8 0.0 0.097 12.2 0.0 1.2 1 0 0 1 1 1 0 Immune evasion protein Peptidase_M56 PF05569.11 ORY14245.1 - 0.12 11.5 0.0 0.18 10.9 0.0 1.1 1 0 0 1 1 1 0 BlaR1 peptidase M56 Amidase PF01425.21 ORY14246.1 - 4.4e-44 151.2 0.1 7.6e-44 150.4 0.1 1.4 1 0 0 1 1 1 1 Amidase RNA_pol_3_Rpc31 PF11705.8 ORY14249.1 - 4.5e-43 148.1 6.3 5.5e-43 147.8 6.3 1.1 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 DNA_pol_phi PF04931.13 ORY14249.1 - 2.6 6.1 19.2 3.1 5.8 19.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi Astro_capsid_p PF12226.8 ORY14249.1 - 7.9 5.5 18.8 10 5.2 18.8 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Meth_synt_2 PF01717.18 ORY14251.1 - 1.4e-12 47.5 0.0 1.5e-08 34.3 0.0 2.3 2 1 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain CKS PF01111.19 ORY14251.1 - 0.0023 18.2 0.0 0.022 15.0 0.0 2.3 2 0 0 2 2 2 1 Cyclin-dependent kinase regulatory subunit Meth_synt_1 PF08267.12 ORY14251.1 - 0.017 14.7 0.0 0.048 13.2 0.0 2.0 2 1 0 2 2 2 0 Cobalamin-independent synthase, N-terminal domain Epimerase PF01370.21 ORY14252.1 - 4.4e-18 65.6 0.0 6.2e-18 65.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 ORY14252.1 - 7e-10 38.4 0.0 1e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 ORY14252.1 - 3.7e-09 36.1 0.0 3.5e-08 32.9 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 ORY14252.1 - 2.2e-07 30.6 0.2 2.2e-06 27.3 0.2 2.3 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 ORY14252.1 - 4.3e-05 23.2 2.2 0.13 11.8 0.0 2.7 2 1 0 2 2 2 2 NmrA-like family KR PF08659.10 ORY14252.1 - 0.00069 19.6 0.0 0.0012 18.7 0.0 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 ORY14252.1 - 0.0014 18.6 0.5 0.0027 17.6 0.0 1.7 2 1 0 2 2 2 1 NAD(P)H-binding adh_short PF00106.25 ORY14252.1 - 0.038 13.4 0.0 0.076 12.5 0.0 1.5 1 0 0 1 1 1 0 short chain dehydrogenase RSN1_7TM PF02714.15 ORY14253.1 - 7e-76 255.1 22.6 7e-76 255.1 22.6 1.7 3 0 0 3 3 3 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 ORY14253.1 - 1.5e-41 142.6 0.1 2.2e-41 142.0 0.1 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 ORY14253.1 - 1.4e-34 119.1 3.2 1.4e-34 119.1 3.2 2.0 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport ABC_tran_CTD PF16326.5 ORY14253.1 - 0.18 12.0 0.5 27 5.1 0.0 2.4 2 0 0 2 2 2 0 ABC transporter C-terminal domain GFO_IDH_MocA PF01408.22 ORY14255.1 - 1.2e-10 42.3 0.0 3.8e-10 40.6 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 ORY14255.1 - 0.0092 16.0 0.0 0.022 14.7 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain UCH PF00443.29 ORY14256.1 - 3e-39 135.1 0.1 7.7e-35 120.6 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 ORY14256.1 - 1.9e-08 34.3 1.5 1e-06 28.6 1.5 2.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF4183 PF13799.6 ORY14256.1 - 0.19 11.5 0.0 0.42 10.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4183) Ribosomal_L9_N PF01281.19 ORY14257.1 - 8.6e-07 28.4 0.0 1.6e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain Ribosomal_L9_C PF03948.14 ORY14257.1 - 0.03 14.8 0.0 0.076 13.5 0.0 1.6 1 1 0 1 1 1 0 Ribosomal protein L9, C-terminal domain F_bP_aldolase PF01116.20 ORY14258.1 - 6.8e-94 314.5 0.0 7.6e-94 314.3 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Amidohydro_1 PF01979.20 ORY14260.1 - 1.5e-75 254.7 0.0 1.8e-75 254.4 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 ORY14260.1 - 2.4e-11 43.8 1.4 1.6e-08 34.5 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family A_deaminase PF00962.22 ORY14260.1 - 0.00054 19.4 0.0 0.00095 18.6 0.0 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase Actin PF00022.19 ORY14261.1 - 2.7e-22 79.0 0.0 4.5e-17 61.7 0.0 2.9 3 0 0 3 3 3 2 Actin cNMP_binding PF00027.29 ORY14262.1 - 4.9e-27 93.8 0.0 7.6e-16 58.0 0.0 5.4 4 1 1 5 5 5 4 Cyclic nucleotide-binding domain Patatin PF01734.22 ORY14262.1 - 5.3e-16 59.4 10.2 9.8e-16 58.5 6.2 2.9 2 1 0 2 2 2 1 Patatin-like phospholipase GDC-P PF02347.16 ORY14263.1 - 2e-171 570.6 0.0 2.9e-159 530.5 0.0 2.4 2 1 0 2 2 2 2 Glycine cleavage system P-protein Aminotran_5 PF00266.19 ORY14263.1 - 1.2e-08 34.3 0.0 4.6e-06 25.8 0.0 2.3 2 0 0 2 2 2 2 Aminotransferase class-V Beta_elim_lyase PF01212.21 ORY14263.1 - 1.1e-05 24.9 0.0 2.8e-05 23.6 0.0 1.6 2 0 0 2 2 2 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 ORY14263.1 - 0.022 14.0 0.0 0.036 13.4 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Glyco_hydro_65N PF03636.15 ORY14264.1 - 8.8e-35 120.4 0.0 1.3e-34 119.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_65m PF03632.15 ORY14264.1 - 3.6e-30 105.1 0.9 8.7e-28 97.2 0.3 2.3 1 1 1 2 2 2 2 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65C PF03633.15 ORY14264.1 - 6.2e-05 22.8 0.5 0.00094 19.0 0.1 3.0 3 0 0 3 3 3 1 Glycosyl hydrolase family 65, C-terminal domain F5_F8_type_C PF00754.25 ORY14264.1 - 0.0021 18.1 0.1 0.0097 16.0 0.0 2.2 2 0 0 2 2 2 1 F5/8 type C domain YL1 PF05764.13 ORY14265.1 - 0.24 11.5 5.6 0.36 10.9 5.6 1.3 1 0 0 1 1 1 0 YL1 nuclear protein NOA36 PF06524.12 ORY14265.1 - 0.43 9.9 4.0 0.69 9.2 4.0 1.3 1 0 0 1 1 1 0 NOA36 protein Synaptobrevin PF00957.21 ORY14267.1 - 1.3e-13 50.5 0.4 2.3e-13 49.7 0.4 1.4 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 ORY14267.1 - 5.1e-10 39.3 0.0 9.2e-10 38.4 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Sec63 PF02889.16 ORY14268.1 - 7e-135 448.1 0.0 2.6e-81 272.6 0.1 2.2 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 ORY14268.1 - 1.3e-51 174.9 0.0 6.2e-27 94.5 0.5 3.0 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.15 ORY14268.1 - 3.4e-20 72.7 0.0 1.1e-09 38.5 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 ORY14268.1 - 1.7e-15 57.3 0.0 1.1e-06 29.0 0.0 3.8 2 2 0 2 2 2 2 Helicase conserved C-terminal domain AAA_30 PF13604.6 ORY14268.1 - 1.1e-06 28.5 0.1 0.0055 16.4 0.2 2.8 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.6 ORY14268.1 - 2e-06 28.1 1.4 0.12 12.7 0.0 4.0 2 2 0 2 2 2 2 AAA domain AAA_19 PF13245.6 ORY14268.1 - 9.4e-06 26.0 2.4 0.00071 19.9 0.6 3.0 3 0 0 3 3 3 1 AAA domain Helicase_PWI PF18149.1 ORY14268.1 - 3.3e-05 24.0 0.0 0.0001 22.5 0.0 1.8 1 0 0 1 1 1 1 N-terminal helicase PWI domain SesA PF17107.5 ORY14269.1 - 4.5e-12 46.2 0.0 8.9e-12 45.3 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases TPR_10 PF13374.6 ORY14269.1 - 4.7e-11 42.2 0.0 0.015 15.1 0.0 4.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 ORY14269.1 - 9.1e-10 38.7 0.0 0.00021 21.5 0.0 3.5 2 1 0 3 3 3 2 Tetratricopeptide repeat NB-ARC PF00931.22 ORY14269.1 - 4e-05 22.9 0.0 0.15 11.2 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain TPR_5 PF12688.7 ORY14269.1 - 0.047 13.9 0.1 18 5.6 0.0 2.7 2 0 0 2 2 2 0 Tetratrico peptide repeat ATPase_2 PF01637.18 ORY14269.1 - 0.13 12.2 0.1 4 7.3 0.0 2.4 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea DUF4250 PF14056.6 ORY14269.1 - 0.14 12.2 0.4 0.5 10.4 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4250) NusB PF01029.18 ORY14269.1 - 0.18 12.0 0.9 25 5.1 0.0 2.9 3 0 0 3 3 3 0 NusB family Na_Ala_symp PF01235.17 ORY14270.1 - 0.061 12.6 0.1 0.061 12.6 0.1 1.9 2 1 0 2 2 2 0 Sodium:alanine symporter family Lipin_mid PF16876.5 ORY14270.1 - 0.098 12.8 0.1 0.23 11.7 0.1 1.5 1 0 0 1 1 1 0 Lipin/Ned1/Smp2 multi-domain protein middle domain SOG2 PF10428.9 ORY14271.1 - 0.39 9.9 5.7 0.42 9.8 5.7 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein SNF2_N PF00176.23 ORY14273.1 - 8.9e-64 215.4 0.3 2.7e-63 213.8 0.0 1.8 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ORY14273.1 - 2.4e-20 72.9 0.0 5.7e-20 71.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY14273.1 - 1.3e-08 35.1 0.0 7.4e-08 32.6 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 ORY14273.1 - 0.00073 18.8 0.0 0.0014 17.8 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Senescence_reg PF04520.13 ORY14273.1 - 0.045 14.6 9.2 0.054 14.3 0.2 2.8 2 0 0 2 2 2 0 Senescence regulator ABC_tran_CTD PF16326.5 ORY14273.1 - 0.22 11.8 8.0 0.13 12.5 1.5 3.3 2 1 1 3 3 3 0 ABC transporter C-terminal domain JAKMIP_CC3 PF16034.5 ORY14273.1 - 7.9 6.4 15.0 0.42 10.5 3.6 3.3 3 0 0 3 3 3 0 JAKMIP CC3 domain AMP-binding PF00501.28 ORY14274.1 - 1e-28 100.1 0.0 1.8e-28 99.3 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme DJ-1_PfpI PF01965.24 ORY14276.1 - 1.1e-08 35.1 0.0 1.4e-08 34.7 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family SHE3 PF17078.5 ORY14278.1 - 0.029 14.1 0.2 0.093 12.4 0.1 1.6 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 Bac_rhamnosid6H PF17389.2 ORY14279.1 - 3.3e-08 33.2 0.2 1.6e-06 27.6 0.2 2.1 2 0 0 2 2 2 2 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_C PF17390.2 ORY14279.1 - 7.4e-07 28.9 0.0 1.6e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain Trehalase PF01204.18 ORY14279.1 - 0.00021 20.3 0.4 0.00031 19.7 0.4 1.1 1 0 0 1 1 1 1 Trehalase DUF4078 PF13300.6 ORY14283.1 - 3.2e-27 94.7 12.7 3.2e-27 94.7 12.7 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF4078) Homoserine_dh PF00742.19 ORY14284.1 - 1.5e-51 174.8 0.0 1.9e-51 174.4 0.0 1.1 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 ORY14284.1 - 3.8e-15 56.6 0.0 6.8e-15 55.8 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain ATG11 PF10377.9 ORY14286.1 - 3.4e-46 156.5 0.0 3.4e-46 156.5 0.0 4.1 4 1 1 5 5 5 1 Autophagy-related protein 11 APG17 PF04108.12 ORY14286.1 - 8e-05 21.9 7.1 0.00053 19.2 4.6 5.5 3 2 1 4 4 4 2 Autophagy protein Apg17 Baculo_F PF12259.8 ORY14286.1 - 0.023 13.2 1.8 0.13 10.7 0.0 2.3 2 0 0 2 2 2 0 Baculovirus F protein Fez1 PF06818.15 ORY14286.1 - 0.079 13.4 56.4 0.025 15.0 12.3 5.2 1 1 2 3 3 3 0 Fez1 DUF1319 PF07028.11 ORY14286.1 - 0.28 11.4 6.2 12 6.2 0.1 4.8 4 1 0 4 4 4 0 Protein of unknown function (DUF1319) CENP-H PF05837.12 ORY14287.1 - 5.6e-26 91.2 1.5 5.6e-26 91.2 1.5 2.1 2 0 0 2 2 2 1 Centromere protein H (CENP-H) GalKase_gal_bdg PF10509.9 ORY14287.1 - 0.019 14.5 0.0 0.04 13.5 0.0 1.4 1 0 0 1 1 1 0 Galactokinase galactose-binding signature FadA PF09403.10 ORY14287.1 - 0.082 13.4 0.7 0.082 13.4 0.7 2.2 2 1 0 2 2 2 0 Adhesion protein FadA HMG_box PF00505.19 ORY14289.1 - 8.8e-26 90.1 2.8 1.3e-25 89.5 2.8 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 ORY14289.1 - 5.3e-18 65.4 3.7 9.6e-18 64.6 3.7 1.5 1 0 0 1 1 1 1 HMG-box domain Ccdc124 PF06244.12 ORY14289.1 - 0.0086 16.6 0.1 0.0086 16.6 0.1 2.2 1 1 1 2 2 2 1 Coiled-coil domain-containing protein 124 /Oxs1 CHDNT PF08073.12 ORY14289.1 - 0.024 14.6 0.0 0.036 14.0 0.0 1.2 1 0 0 1 1 1 0 CHDNT (NUC034) domain HMG_box_5 PF14887.6 ORY14289.1 - 0.82 9.7 6.7 0.072 13.1 2.1 1.6 2 0 0 2 2 2 0 HMG (high mobility group) box 5 Peptidase_S24 PF00717.23 ORY14290.1 - 1.7e-07 31.1 0.0 2.4e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like PWWP PF00855.17 ORY14291.1 - 0.0037 17.6 0.1 0.04 14.3 0.0 2.6 3 0 0 3 3 3 1 PWWP domain DUF402 PF04167.13 ORY14292.1 - 0.18 12.0 0.0 0.26 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF402) MORN_2 PF07661.13 ORY14292.1 - 0.3 11.5 2.1 0.94 9.9 0.1 2.4 2 0 0 2 2 2 0 MORN repeat variant GMC_oxred_N PF00732.19 ORY14293.1 - 3.9e-58 197.2 0.0 5.2e-58 196.8 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 ORY14293.1 - 1.2e-30 106.9 0.0 2.3e-30 106.0 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 ORY14293.1 - 8.5e-05 21.8 0.0 0.007 15.5 0.0 2.5 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 ORY14293.1 - 0.00013 22.1 0.0 0.00032 20.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ORY14293.1 - 0.00014 21.6 0.3 0.00044 19.9 0.3 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 ORY14293.1 - 0.00026 20.3 0.0 0.017 14.4 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ORY14293.1 - 0.0024 17.2 0.0 0.019 14.2 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Catalase PF00199.19 ORY14293.1 - 0.014 14.5 0.0 0.022 13.9 0.0 1.2 1 0 0 1 1 1 0 Catalase Pyr_redox PF00070.27 ORY14293.1 - 0.015 15.8 0.0 0.051 14.1 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 ORY14293.1 - 0.058 12.4 0.0 0.085 11.9 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.17 ORY14293.1 - 0.066 12.5 0.2 0.67 9.2 0.1 2.3 2 0 0 2 2 2 0 Thi4 family MtrD PF04207.12 ORY14293.1 - 0.08 12.6 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit D HI0933_like PF03486.14 ORY14293.1 - 0.083 11.6 0.1 1.9 7.1 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein GIDA PF01134.22 ORY14293.1 - 0.084 11.9 0.0 8.4 5.4 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A TrkA_N PF02254.18 ORY14293.1 - 0.095 13.0 0.1 0.21 11.9 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_9 PF13454.6 ORY14293.1 - 0.12 12.4 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding BTB PF00651.31 ORY14295.1 - 5.2e-05 23.4 0.0 0.00012 22.3 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Ala_racemase_N PF01168.20 ORY14296.1 - 8.3e-25 87.7 0.0 1e-24 87.4 0.0 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain T7SS_ESX_EspC PF10824.8 ORY14296.1 - 0.17 12.4 0.3 2.1 8.9 0.2 2.3 2 0 0 2 2 2 0 Excreted virulence factor EspC, type VII ESX diderm DUF3040 PF11239.8 ORY14297.1 - 0.25 11.6 0.3 0.45 10.8 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) OAD_gamma PF04277.13 ORY14299.1 - 2.7 8.7 4.3 14 6.3 4.3 2.3 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Peptidase_S49_N PF08496.10 ORY14299.1 - 4.8 7.2 12.9 0.052 13.6 4.8 1.8 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Aldose_epim PF01263.20 ORY14300.1 - 4.4e-51 174.0 1.8 5.2e-51 173.7 1.8 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase TauD PF02668.16 ORY14301.1 - 1.1e-43 150.0 0.1 1.6e-43 149.5 0.1 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family FadA PF09403.10 ORY14301.1 - 0.11 13.0 0.1 0.32 11.5 0.1 1.8 1 0 0 1 1 1 0 Adhesion protein FadA Abhydrolase_6 PF12697.7 ORY14302.1 - 3.5e-05 24.5 0.7 0.00019 22.1 0.7 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.7 ORY14302.1 - 0.092 11.6 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme CAAX_1 PF15895.5 ORY14303.1 - 0.0051 16.7 2.8 0.0088 16.0 2.3 1.5 2 0 0 2 2 2 1 CAAX box cerebral protein 1 MS_channel PF00924.18 ORY14304.1 - 2.2e-17 63.3 1.0 3.8e-17 62.5 1.0 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.32 ORY14304.1 - 0.0043 16.5 0.1 0.011 15.3 0.1 1.7 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 ORY14304.1 - 0.011 15.7 0.0 0.045 13.7 0.0 2.1 1 0 0 1 1 1 0 EF-hand domain EF-hand_5 PF13202.6 ORY14304.1 - 0.014 14.9 0.3 0.037 13.5 0.0 1.9 2 0 0 2 2 2 0 EF hand EF-hand_7 PF13499.6 ORY14304.1 - 0.015 15.8 0.1 0.043 14.3 0.1 1.8 1 0 0 1 1 1 0 EF-hand domain pair Nab6_mRNP_bdg PF10567.9 ORY14304.1 - 0.16 11.4 0.6 0.28 10.6 0.6 1.2 1 0 0 1 1 1 0 RNA-recognition motif GETHR PF05671.11 ORY14305.1 - 0.33 10.4 2.6 1.2 8.6 0.0 2.6 2 1 0 2 2 2 0 GETHR pentapeptide repeat (5 copies) DUF4032 PF13224.6 ORY14306.1 - 0.0091 15.9 0.0 0.011 15.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4032) Helo_like_N PF17111.5 ORY14306.1 - 0.012 15.0 0.2 0.15 11.4 0.0 2.0 2 0 0 2 2 2 0 Fungal N-terminal domain of STAND proteins CR6_interact PF10147.9 ORY14306.1 - 0.041 13.6 0.0 0.049 13.3 0.0 1.1 1 0 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 Ank_4 PF13637.6 ORY14308.1 - 2.6e-15 56.6 0.5 2.8e-08 34.1 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 ORY14308.1 - 3.7e-11 42.9 1.1 9.6e-06 25.8 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 ORY14308.1 - 1.2e-09 38.6 0.3 2.3e-07 31.3 0.1 2.0 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ORY14308.1 - 0.0001 22.5 0.2 0.00016 21.9 0.2 1.4 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY14308.1 - 0.00018 21.7 0.1 0.063 13.9 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 ORY14309.1 - 2.9e-21 75.5 0.3 3.6e-10 40.2 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 ORY14309.1 - 6.3e-17 61.2 1.3 2.1e-05 24.8 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.7 ORY14309.1 - 2.3e-14 53.7 0.5 1e-13 51.7 0.5 2.2 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ORY14309.1 - 7e-09 35.8 2.1 1.7e-05 25.0 0.1 2.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY14309.1 - 2e-07 30.8 0.1 0.022 15.2 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat DUF1966 PF09260.11 ORY14309.1 - 0.033 14.4 0.1 0.36 11.2 0.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF1966) AAA_22 PF13401.6 ORY14310.1 - 1.3e-06 28.8 0.4 1.6e-05 25.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 ORY14310.1 - 4.6e-06 26.7 0.1 2.9e-05 24.0 0.0 2.2 2 0 0 2 2 2 1 NACHT domain ATPase PF06745.13 ORY14310.1 - 0.0023 17.3 0.0 0.0039 16.6 0.0 1.4 1 0 0 1 1 1 1 KaiC DUF4777 PF16007.5 ORY14310.1 - 0.085 13.1 0.0 6.7 7.0 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4777) AAA_19 PF13245.6 ORY14310.1 - 0.098 13.0 0.0 0.25 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF383 PF04063.14 ORY14312.1 - 1.2e-63 214.3 0.0 2.6e-63 213.2 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF383) DUF384 PF04064.13 ORY14312.1 - 4.5e-21 74.5 2.1 1.3e-20 73.0 2.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF384) MFS_1 PF07690.16 ORY14313.1 - 1.8e-15 56.8 34.5 1.8e-15 56.8 34.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Flavi_NS4A PF01350.17 ORY14313.1 - 0.42 10.5 2.9 1 9.3 2.9 1.6 1 0 0 1 1 1 0 Flavivirus non-structural protein NS4A Acylphosphatase PF00708.18 ORY14314.1 - 0.32 11.4 1.0 10 6.6 0.2 2.5 2 0 0 2 2 2 0 Acylphosphatase TFIIF_alpha PF05793.12 ORY14314.1 - 1.9 7.0 71.7 0.92 8.0 48.6 3.6 1 1 2 3 3 3 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PAP_assoc PF03828.19 ORY14315.1 - 5.1e-19 68.2 0.0 1.3e-18 67.0 0.0 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 ORY14315.1 - 2.9e-05 24.3 0.0 0.00012 22.3 0.0 2.0 2 0 0 2 2 2 1 Nucleotidyltransferase domain Polbeta PF18765.1 ORY14315.1 - 0.004 17.2 0.0 0.0094 16.0 0.0 1.6 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase PAP_central PF04928.17 ORY14315.1 - 0.094 11.7 0.3 0.29 10.1 0.2 1.8 2 0 0 2 2 2 0 Poly(A) polymerase central domain Sugar_tr PF00083.24 ORY14316.1 - 2.5e-108 362.9 15.0 2.9e-108 362.7 15.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY14316.1 - 4.4e-24 85.1 20.8 4.4e-24 85.1 20.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 ORY14316.1 - 0.016 13.6 5.0 0.027 12.9 5.0 1.3 1 0 0 1 1 1 0 Transmembrane secretion effector DUF3147 PF11345.8 ORY14316.1 - 0.4 11.1 8.1 7.9 6.9 0.0 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3147) DUF4131 PF13567.6 ORY14316.1 - 1.1 8.9 0.0 1.1 8.9 0.0 2.6 4 0 0 4 4 4 0 Domain of unknown function (DUF4131) UQ_con PF00179.26 ORY14318.1 - 2e-19 69.7 0.0 2.8e-19 69.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF2169 PF09937.9 ORY14318.1 - 0.13 11.7 0.2 0.18 11.2 0.2 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2169) Bac_surface_Ag PF01103.23 ORY14319.1 - 7.1e-46 157.2 0.5 9.2e-46 156.8 0.5 1.1 1 0 0 1 1 1 1 Surface antigen adh_short PF00106.25 ORY14321.1 - 1.2e-08 34.6 0.2 1e-07 31.6 0.1 2.3 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY14321.1 - 0.0077 15.8 0.1 0.024 14.2 0.1 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase RlmM_FDX PF18125.1 ORY14321.1 - 0.19 12.2 0.0 14 6.3 0.0 2.5 2 0 0 2 2 2 0 RlmM ferredoxin-like domain FAD_binding_4 PF01565.23 ORY14324.1 - 8.5e-24 83.9 6.4 1.4e-23 83.2 6.4 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 ORY14324.1 - 2.8e-12 46.5 0.2 8e-12 45.1 0.2 1.8 1 0 0 1 1 1 1 Berberine and berberine like Emaravirus_P4 PF16505.5 ORY14324.1 - 0.1 11.6 0.1 0.16 11.0 0.1 1.2 1 0 0 1 1 1 0 P4 movement protein of Emaravirus, and the 30K superfamily Lactonase PF10282.9 ORY14325.1 - 1.2e-85 287.8 0.1 2.5e-85 286.8 0.1 1.4 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller dCMP_cyt_deam_1 PF00383.23 ORY14325.1 - 7.2e-07 29.0 0.2 0.00044 20.1 0.0 2.7 2 1 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region Sugar_tr PF00083.24 ORY14326.1 - 4e-57 194.1 4.2 4.8e-57 193.8 4.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY14326.1 - 1.8e-18 66.6 8.4 2.4e-18 66.2 8.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 ORY14326.1 - 0.0019 16.7 2.2 0.0025 16.3 2.2 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2721 PF11026.8 ORY14326.1 - 0.021 14.7 6.0 0.48 10.3 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2721) OATP PF03137.20 ORY14326.1 - 0.11 10.7 1.4 0.14 10.4 1.4 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family HisKA_7TM PF16927.5 ORY14326.1 - 0.18 11.8 8.7 0.17 11.9 2.6 2.2 1 1 1 2 2 2 0 N-terminal 7TM region of histidine kinase Sugar_tr PF00083.24 ORY14327.1 - 7.8e-38 130.5 12.8 8.7e-38 130.3 12.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY14327.1 - 8.2e-10 38.1 5.8 8.9e-10 38.0 5.8 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Herpes_LMP1 PF05297.11 ORY14327.1 - 8.2e-06 25.3 0.3 1e-05 24.9 0.3 1.1 1 0 0 1 1 1 1 Herpesvirus latent membrane protein 1 (LMP1) Bax1-I PF01027.20 ORY14327.1 - 0.016 15.0 10.4 0.026 14.3 10.4 1.3 1 1 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 DUF3021 PF11457.8 ORY14327.1 - 1.2 9.5 11.0 0.31 11.4 7.8 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3021) Pkinase PF00069.25 ORY14329.1 - 2.5e-16 59.8 0.0 1.1e-15 57.8 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY14329.1 - 0.00079 18.8 0.0 0.011 15.1 0.0 2.5 2 1 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 ORY14329.1 - 0.022 14.7 0.1 0.036 14.0 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 ORY14329.1 - 0.048 13.0 0.0 0.078 12.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DpnD-PcfM PF14207.6 ORY14329.1 - 0.05 13.5 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 DpnD/PcfM-like protein RIO1 PF01163.22 ORY14329.1 - 0.079 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 RIO1 family WD40 PF00400.32 ORY14330.1 - 0.14 13.1 3.8 0.67 10.9 0.0 3.8 5 0 0 5 5 5 0 WD domain, G-beta repeat HTH_Tnp_1 PF01527.20 ORY14331.1 - 0.22 11.8 3.6 0.87 9.9 1.6 2.6 1 1 1 2 2 2 0 Transposase RINGv PF12906.7 ORY14333.1 - 7.8e-06 25.9 5.5 1.4e-05 25.1 5.5 1.5 1 0 0 1 1 1 1 RING-variant domain FANCL_C PF11793.8 ORY14333.1 - 0.00052 20.1 2.0 0.001 19.2 2.0 1.4 1 0 0 1 1 1 1 FANCL C-terminal domain zf-RING_2 PF13639.6 ORY14333.1 - 0.034 14.5 4.4 0.062 13.7 4.4 1.5 1 0 0 1 1 1 0 Ring finger domain EphA2_TM PF14575.6 ORY14334.1 - 0.094 13.6 0.0 0.17 12.8 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain VPDSG-CTERM PF18205.1 ORY14334.1 - 0.097 12.5 0.8 0.2 11.5 0.8 1.5 1 0 0 1 1 1 0 VPDSG-CTERM motif PTP_tm PF18861.1 ORY14334.1 - 0.13 12.3 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J PEP-CTERM PF07589.11 ORY14334.1 - 0.19 11.8 1.3 0.42 10.8 1.3 1.5 1 0 0 1 1 1 0 PEP-CTERM motif TANGO2 PF05742.12 ORY14337.1 - 1.9e-75 254.2 0.0 2.2e-75 254.0 0.0 1.0 1 0 0 1 1 1 1 Transport and Golgi organisation 2 SpoIIIAH PF12685.7 ORY14339.1 - 0.053 13.3 0.1 0.053 13.3 0.1 2.1 1 1 1 2 2 2 0 SpoIIIAH-like protein DUF3112 PF11309.8 ORY14340.1 - 1.1e-10 41.3 1.2 1e-09 38.2 0.1 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF3112) Zn_clus PF00172.18 ORY14341.1 - 4.3e-08 33.1 7.8 8.5e-08 32.2 7.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 ORY14341.1 - 7.3e-07 28.3 0.3 7.3e-07 28.3 0.3 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF4690 PF15756.5 ORY14342.1 - 0.0056 17.2 2.5 0.0056 17.2 2.5 2.3 2 1 0 2 2 2 1 Small Novel Rich in Cartilage Podoplanin PF05808.11 ORY14342.1 - 0.07 13.2 0.3 0.13 12.3 0.1 1.5 2 0 0 2 2 2 0 Podoplanin DUF4653 PF15546.6 ORY14342.1 - 0.68 9.5 5.9 1.2 8.8 5.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4653) FAM163 PF15069.6 ORY14343.1 - 0.025 15.0 0.1 0.071 13.5 0.0 1.7 2 0 0 2 2 2 0 FAM163 family RIFIN PF02009.16 ORY14343.1 - 0.029 14.3 0.0 0.045 13.6 0.0 1.3 1 0 0 1 1 1 0 Rifin Amnionless PF14828.6 ORY14343.1 - 0.042 12.7 0.0 0.049 12.5 0.0 1.2 1 0 0 1 1 1 0 Amnionless DUF2207 PF09972.9 ORY14343.1 - 0.12 11.1 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) VSP PF03302.13 ORY14343.1 - 0.17 10.7 1.4 0.21 10.4 1.4 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein DUF4690 PF15756.5 ORY14343.1 - 0.48 11.1 4.8 1 10.0 4.7 1.7 1 1 0 1 1 1 0 Small Novel Rich in Cartilage GPI-anchored PF10342.9 ORY14344.1 - 0.00099 19.8 0.1 0.0025 18.5 0.1 1.7 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family CD34_antigen PF06365.12 ORY14344.1 - 0.17 11.4 0.1 0.28 10.7 0.1 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family Mucin PF01456.17 ORY14344.1 - 0.56 10.2 17.1 0.06 13.3 12.6 1.8 2 0 0 2 2 2 0 Mucin-like glycoprotein GPI-anchored PF10342.9 ORY14345.1 - 0.0022 18.7 0.9 0.008 16.9 0.0 2.3 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family SOG2 PF10428.9 ORY14345.1 - 4.8 6.3 9.2 6.3 5.9 9.2 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Methyltransf_2 PF00891.18 ORY14346.1 - 6.2e-26 91.0 0.0 8.4e-26 90.6 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 ORY14346.1 - 0.005 16.8 0.0 0.012 15.6 0.0 1.5 1 0 0 1 1 1 1 Dimerisation domain Dimerisation PF08100.11 ORY14346.1 - 0.15 12.1 0.0 0.34 11.0 0.0 1.6 1 0 0 1 1 1 0 Dimerisation domain Ank_2 PF12796.7 ORY14347.1 - 9e-17 61.4 3.3 9.2e-11 42.2 0.1 3.6 1 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY14347.1 - 7.3e-16 58.3 2.3 1.1e-08 35.4 0.0 4.9 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 ORY14347.1 - 1.9e-09 37.6 1.7 6.9e-06 26.2 0.3 4.0 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 ORY14347.1 - 8.2e-09 35.5 0.5 0.0027 18.1 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 ORY14347.1 - 9.7e-08 31.7 1.9 0.83 10.4 0.0 6.4 6 0 0 6 6 6 2 Ankyrin repeat NACHT PF05729.12 ORY14347.1 - 2.7e-06 27.4 0.0 7.6e-06 25.9 0.0 1.8 1 0 0 1 1 1 1 NACHT domain DUF676 PF05057.14 ORY14347.1 - 0.00024 20.7 0.0 0.0022 17.5 0.0 2.3 2 0 0 2 2 2 1 Putative serine esterase (DUF676) AAA_16 PF13191.6 ORY14347.1 - 0.0066 16.9 0.1 0.02 15.3 0.1 1.8 1 0 0 1 1 1 1 AAA ATPase domain LCAT PF02450.15 ORY14347.1 - 0.09 11.9 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase KAP_NTPase PF07693.14 ORY14347.1 - 0.11 11.8 0.2 3.4 6.8 0.0 2.3 2 0 0 2 2 2 0 KAP family P-loop domain RNA_helicase PF00910.22 ORY14347.1 - 0.12 12.8 0.0 0.84 10.1 0.0 2.4 2 0 0 2 2 2 0 RNA helicase Cutinase PF01083.22 ORY14347.1 - 0.18 11.8 0.0 17 5.3 0.0 2.3 2 0 0 2 2 2 0 Cutinase DUF2235 PF09994.9 ORY14348.1 - 8.7e-81 271.4 0.0 1.2e-80 271.0 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Methyltransf_23 PF13489.6 ORY14351.1 - 1.7e-27 96.3 0.0 2.6e-27 95.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY14351.1 - 3.6e-07 30.8 0.0 6.3e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY14351.1 - 3.5e-05 24.4 0.0 6.2e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY14351.1 - 0.00023 21.0 0.0 0.00037 20.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY14351.1 - 0.00027 21.6 0.0 0.00051 20.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Pex14_N PF04695.13 ORY14351.1 - 0.036 14.7 0.7 0.066 13.9 0.7 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DAO PF01266.24 ORY14352.1 - 5.6e-40 138.0 0.0 6.7e-40 137.8 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ORY14352.1 - 0.00045 20.4 0.0 0.0031 17.7 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 ORY14352.1 - 0.00073 19.5 0.0 0.038 14.0 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 ORY14352.1 - 0.0065 15.7 0.0 0.16 11.1 0.0 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 ORY14352.1 - 0.01 15.0 0.0 0.014 14.5 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Glyco_hydro_75 PF07335.11 ORY14365.1 - 2.6e-59 200.2 0.2 3.3e-59 199.8 0.2 1.1 1 0 0 1 1 1 1 Fungal chitosanase of glycosyl hydrolase group 75 BTB PF00651.31 ORY14367.1 - 1.7e-05 25.0 0.0 0.00011 22.4 0.0 2.0 1 1 1 2 2 2 1 BTB/POZ domain Pro-kuma_activ PF09286.11 ORY14368.1 - 9.5e-47 158.9 0.0 3.3e-45 153.9 0.0 2.2 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 ORY14368.1 - 0.0051 16.1 0.1 0.0093 15.3 0.1 1.3 1 0 0 1 1 1 1 Subtilase family Tannase PF07519.11 ORY14369.1 - 1.2e-08 34.3 0.0 1.4e-08 34.1 0.0 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Epimerase PF01370.21 ORY14370.1 - 5.3e-13 49.0 0.0 3.3e-12 46.4 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 ORY14370.1 - 2e-11 43.5 0.0 2.8e-08 33.3 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein NmrA PF05368.13 ORY14370.1 - 1.5e-10 41.0 0.0 6.8e-09 35.6 0.0 2.1 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.6 ORY14370.1 - 3.9e-09 36.7 0.0 5.4e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 ORY14370.1 - 1.6e-07 30.6 0.0 2.2e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 ORY14370.1 - 1.7e-06 27.7 0.0 2.5e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 ORY14370.1 - 0.036 13.5 0.3 0.13 11.7 0.3 1.9 1 1 0 1 1 1 0 short chain dehydrogenase KR PF08659.10 ORY14370.1 - 0.15 12.0 0.7 2 8.3 0.7 2.1 1 1 0 1 1 1 0 KR domain FAD_binding_4 PF01565.23 ORY14372.1 - 3.8e-23 81.8 0.1 6.3e-23 81.0 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.19 ORY14372.1 - 7.7e-13 48.6 0.0 1.4e-12 47.8 0.0 1.4 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain ADH_zinc_N PF00107.26 ORY14373.1 - 4.6e-27 94.6 0.2 6.8e-27 94.0 0.2 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ORY14373.1 - 1.5e-23 82.8 4.6 3.2e-23 81.7 2.7 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 ORY14373.1 - 6.4e-10 40.2 0.0 1.2e-09 39.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 ORY14373.1 - 0.00075 19.0 0.1 0.0011 18.5 0.1 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus Fer4_8 PF13183.6 ORY14373.1 - 0.031 14.7 1.3 0.13 12.8 0.3 2.2 2 0 0 2 2 2 0 4Fe-4S dicluster domain adh_short PF00106.25 ORY14373.1 - 0.18 11.2 3.1 0.41 10.1 3.1 1.6 1 1 0 1 1 1 0 short chain dehydrogenase DapB_N PF01113.20 ORY14373.1 - 2.4 8.3 4.4 37 4.5 4.4 2.3 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus DUF5537 PF17690.1 ORY14374.1 - 0.12 12.0 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5537) Pkinase PF00069.25 ORY14375.1 - 0.00065 19.2 0.1 0.027 13.8 0.0 2.7 2 1 0 2 2 2 1 Protein kinase domain MFAP1 PF06991.11 ORY14376.1 - 1.5e-68 230.9 35.0 1.5e-68 230.9 35.0 2.5 1 1 1 2 2 2 1 Microfibril-associated/Pre-mRNA processing Serglycin PF04360.12 ORY14376.1 - 0.042 13.8 0.8 0.084 12.8 0.8 1.4 1 0 0 1 1 1 0 Serglycin RNA_ligase PF09414.10 ORY14379.1 - 5.7e-10 39.7 0.0 9e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 RNA ligase DUF2630 PF10944.8 ORY14379.1 - 0.073 13.5 0.6 0.21 12.1 0.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2630) IDO PF01231.18 ORY14380.1 - 1.1e-40 139.7 0.0 1.4e-40 139.4 0.0 1.1 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase HrpB2 PF09487.10 ORY14380.1 - 0.067 13.6 0.1 0.13 12.7 0.1 1.4 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB2) Phasin_2 PF09361.10 ORY14380.1 - 0.11 12.7 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 Phasin protein GTP_EFTU PF00009.27 ORY14381.1 - 1.1e-18 67.4 0.0 1.9e-18 66.7 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 ORY14381.1 - 5.4e-09 36.3 1.1 2.8e-08 34.0 0.9 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.17 ORY14381.1 - 8.2e-05 22.9 0.0 0.00019 21.7 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain PduV-EutP PF10662.9 ORY14381.1 - 0.0011 18.8 0.8 0.045 13.5 0.1 3.1 2 1 1 3 3 3 1 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 ORY14381.1 - 0.011 15.9 0.1 0.033 14.2 0.1 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ORY14381.1 - 0.018 15.0 0.9 0.91 9.4 0.0 2.7 3 0 0 3 3 3 0 RsgA GTPase Ank_4 PF13637.6 ORY14382.1 - 9.9e-22 77.0 3.4 3.2e-07 30.8 0.0 4.1 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 ORY14382.1 - 2e-17 63.6 1.8 2.1e-07 31.4 0.2 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 ORY14382.1 - 1.1e-13 51.0 3.3 0.092 13.2 0.0 4.5 4 0 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.6 ORY14382.1 - 6.7e-13 47.6 2.1 0.028 14.9 0.1 4.8 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 ORY14382.1 - 2.4e-08 34.1 3.7 0.014 15.7 0.1 3.8 1 1 1 3 3 3 3 Ankyrin repeats (many copies) FLgD_tudor PF13861.6 ORY14382.1 - 0.00059 20.0 0.9 9.6 6.5 0.0 3.3 3 0 0 3 3 3 2 FlgD Tudor-like domain SesA PF17107.5 ORY14383.1 - 5.7e-24 84.6 1.8 2.6e-23 82.5 0.2 2.6 3 0 0 3 3 3 1 N-terminal domain on NACHT_NTPase and P-loop NTPases NACHT PF05729.12 ORY14383.1 - 1e-08 35.3 0.1 2e-08 34.4 0.1 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 ORY14383.1 - 2.6e-06 28.0 0.0 9.1e-06 26.2 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 ORY14383.1 - 0.00018 21.9 0.0 0.0015 19.0 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Helo_like_N PF17111.5 ORY14383.1 - 0.0022 17.4 0.7 0.0095 15.3 0.1 2.1 2 0 0 2 2 2 1 Fungal N-terminal domain of STAND proteins AAA_22 PF13401.6 ORY14383.1 - 0.0023 18.2 0.0 0.0052 17.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 ORY14383.1 - 0.0035 17.7 0.0 0.009 16.4 0.0 1.7 1 1 0 1 1 1 1 RNA helicase NB-ARC PF00931.22 ORY14383.1 - 0.041 13.1 0.0 0.077 12.2 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_14 PF13173.6 ORY14383.1 - 0.058 13.4 0.0 0.35 10.9 0.0 2.2 1 1 0 1 1 1 0 AAA domain ATPase PF06745.13 ORY14383.1 - 0.11 11.8 0.0 1.2 8.4 0.0 2.4 1 1 0 1 1 1 0 KaiC KAP_NTPase PF07693.14 ORY14383.1 - 0.12 11.6 0.0 8.6 5.5 0.0 2.3 1 1 1 2 2 2 0 KAP family P-loop domain HSP70 PF00012.20 ORY14386.1 - 0.041 12.1 0.0 0.042 12.0 0.0 1.2 1 0 0 1 1 1 0 Hsp70 protein DUF3689 PF12463.8 ORY14386.1 - 0.092 12.0 0.0 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3689) GDPD PF03009.17 ORY14387.1 - 4.7e-17 62.6 0.0 6.7e-17 62.1 0.0 1.4 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family TENA_THI-4 PF03070.16 ORY14388.1 - 3.5e-50 170.7 1.1 4.3e-50 170.4 1.1 1.1 1 0 0 1 1 1 1 TENA/THI-4/PQQC family DUF829 PF05705.14 ORY14389.1 - 2.9e-48 164.9 0.0 3.7e-48 164.5 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) MFS_1 PF07690.16 ORY14390.1 - 1.8e-49 168.6 57.8 1.8e-49 168.6 57.8 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 ORY14390.1 - 2.9e-13 49.1 31.6 3.9e-13 48.7 31.6 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 ORY14390.1 - 1.6e-08 33.8 38.1 4.6e-08 32.3 16.3 2.6 2 0 0 2 2 2 2 Sugar (and other) transporter FMN_bind_2 PF04299.12 ORY14391.1 - 9.1e-07 28.7 0.0 1.1e-06 28.4 0.0 1.1 1 0 0 1 1 1 1 Putative FMN-binding domain SRCR_2 PF15494.6 ORY14392.1 - 0.015 15.8 0.2 0.026 15.0 0.2 1.3 1 0 0 1 1 1 0 Scavenger receptor cysteine-rich domain ADH_N PF08240.12 ORY14396.1 - 9.4e-30 102.7 0.3 1.7e-29 101.9 0.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORY14396.1 - 8e-17 61.4 0.2 1.8e-16 60.3 0.1 1.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 ORY14396.1 - 1.2e-08 34.7 1.6 1.2e-06 28.2 0.5 2.1 1 1 1 2 2 2 2 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 ORY14396.1 - 0.00025 22.1 0.1 0.00049 21.2 0.1 1.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 ORY14396.1 - 0.00048 19.5 0.6 0.00079 18.8 0.6 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_N_assoc PF13823.6 ORY14396.1 - 0.0064 16.4 1.1 0.012 15.6 0.1 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-associated PALP PF00291.25 ORY14396.1 - 0.036 13.5 0.0 0.06 12.7 0.0 1.3 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme Pyr_redox_2 PF07992.14 ORY14396.1 - 0.11 11.7 0.7 0.18 11.0 0.7 1.4 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SOG2 PF10428.9 ORY14397.1 - 3.5 6.7 13.9 4.6 6.3 13.9 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein ADH_N PF08240.12 ORY14398.1 - 1e-26 93.0 2.4 1.7e-26 92.2 2.4 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORY14398.1 - 8e-17 61.4 0.0 1.4e-16 60.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ORY14398.1 - 4.4e-05 24.6 0.0 7.9e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 ORY14398.1 - 0.0017 17.7 1.2 0.087 12.1 0.3 2.2 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Glu_dehyd_C PF16912.5 ORY14398.1 - 0.0045 16.5 0.3 0.0079 15.7 0.3 1.4 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ELFV_dehydrog PF00208.21 ORY14398.1 - 0.014 15.2 0.2 0.024 14.4 0.2 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 2-Hacid_dh_C PF02826.19 ORY14398.1 - 0.11 11.9 0.1 0.19 11.1 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ETC_C1_NDUFA4 PF04800.12 ORY14398.1 - 0.22 11.8 0.1 4 7.8 0.0 2.5 2 1 0 2 2 2 0 ETC complex I subunit conserved region Abhydrolase_6 PF12697.7 ORY14399.1 - 0.00017 22.3 3.9 0.00033 21.3 3.5 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 ORY14399.1 - 0.0012 18.7 0.0 0.0022 17.8 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.14 ORY14399.1 - 0.0014 18.2 0.0 0.0024 17.4 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 ORY14399.1 - 0.026 13.8 0.0 0.05 12.9 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 LCAT PF02450.15 ORY14399.1 - 0.048 12.8 0.0 0.083 12.0 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase LIDHydrolase PF10230.9 ORY14399.1 - 0.18 11.3 0.0 0.27 10.7 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Pro_isomerase PF00160.21 ORY14401.1 - 3.7e-44 150.8 0.0 1.3e-43 149.0 0.0 1.9 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD U-box PF04564.15 ORY14401.1 - 7.4e-05 22.8 0.0 0.00033 20.8 0.0 2.1 1 1 1 2 2 2 1 U-box domain Rtf2 PF04641.12 ORY14401.1 - 0.00039 19.9 0.0 0.0025 17.2 0.0 2.1 1 1 0 1 1 1 1 Rtf2 RING-finger zf-NOSIP PF15906.5 ORY14401.1 - 0.0024 18.0 0.0 0.0053 16.9 0.0 1.6 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein CD24 PF14984.6 ORY14402.1 - 5.1 7.4 10.9 0.61 10.3 3.6 2.3 2 0 0 2 2 2 0 CD24 protein Cyclin PF08613.11 ORY14404.1 - 3.2e-14 53.6 0.0 5.6e-14 52.8 0.0 1.4 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 ORY14404.1 - 0.0027 17.5 0.0 0.0044 16.8 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Ribosomal_L27A PF00828.19 ORY14406.1 - 5e-30 104.8 0.2 5e-30 104.8 0.2 1.6 2 0 0 2 2 2 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A ATG22 PF11700.8 ORY14407.1 - 2.1e-172 574.0 9.9 2.5e-172 573.8 9.9 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 ORY14408.1 - 2e-34 119.1 60.5 2e-34 119.1 60.5 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily Fungal_trans_2 PF11951.8 ORY14409.1 - 3.1e-34 118.4 0.2 4.4e-34 117.9 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY14409.1 - 5.1e-08 32.9 9.3 9.3e-08 32.1 9.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_76 PF03663.14 ORY14410.1 - 3.4e-46 158.4 16.8 1.5e-45 156.4 11.8 2.1 2 0 0 2 2 2 2 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 ORY14410.1 - 0.00021 20.5 1.9 0.00068 18.8 0.0 2.5 1 1 1 2 2 2 1 Glycosyl Hydrolase Family 88 DUF1993 PF09351.10 ORY14411.1 - 9.8e-55 185.1 0.0 1.1e-54 184.9 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) AMP-binding PF00501.28 ORY14412.1 - 3.2e-19 68.9 0.0 4e-19 68.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme LYTB PF02401.18 ORY14412.1 - 0.12 11.6 0.0 0.85 8.8 0.0 2.0 2 0 0 2 2 2 0 LytB protein VKOR PF07884.14 ORY14413.1 - 0.0036 17.5 3.2 0.0042 17.3 3.2 1.1 1 0 0 1 1 1 1 Vitamin K epoxide reductase family CcmF_C PF16327.5 ORY14413.1 - 0.022 14.1 0.1 0.024 13.9 0.1 1.0 1 0 0 1 1 1 0 Cytochrome c-type biogenesis protein CcmF C-terminal Nup188_C PF18378.1 ORY14414.1 - 3.9e-132 440.6 0.1 5.9e-132 440.0 0.1 1.3 1 0 0 1 1 1 1 Nuclear pore protein NUP188 C-terminal domain Nup188 PF10487.9 ORY14414.1 - 5.7e-62 209.9 0.0 1.6e-56 191.8 0.0 2.7 2 1 0 2 2 2 2 Nucleoporin subcomplex protein binding to Pom34 DUF5580 PF17743.1 ORY14414.1 - 0.66 8.4 2.5 2.8 6.4 0.6 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5580) IGPS PF00218.21 ORY14415.1 - 1.2e-96 322.8 0.0 2.2e-96 321.9 0.0 1.4 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase PRAI PF00697.22 ORY14415.1 - 5.3e-45 153.6 2.0 6.3e-41 140.3 0.3 2.9 2 1 1 3 3 3 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase GATase PF00117.28 ORY14415.1 - 7.2e-34 117.2 0.1 9.7e-28 97.2 0.0 2.5 1 1 1 2 2 2 2 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 ORY14415.1 - 0.0001 22.2 0.2 0.00053 19.8 0.2 2.1 1 1 0 1 1 1 1 Peptidase C26 NanE PF04131.14 ORY14415.1 - 0.026 13.7 0.2 0.11 11.7 0.0 2.0 2 0 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase QRPTase_C PF01729.19 ORY14415.1 - 0.074 12.8 1.5 0.35 10.6 0.1 2.4 2 0 0 2 2 2 0 Quinolinate phosphoribosyl transferase, C-terminal domain PTCB-BRCT PF12738.7 ORY14416.1 - 2.3e-05 24.3 0.2 4.7e-05 23.3 0.2 1.6 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 ORY14416.1 - 3.2e-05 24.2 0.0 6.1e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 ORY14416.1 - 0.0008 19.8 0.0 0.0016 18.8 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain Homeodomain PF00046.29 ORY14418.1 - 1.9e-13 50.0 4.6 2.3e-13 49.7 2.4 2.3 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 ORY14418.1 - 0.024 14.5 0.3 0.14 12.0 0.1 2.3 2 0 0 2 2 2 0 Homeobox KN domain NmrA PF05368.13 ORY14420.1 - 3.7e-06 26.7 0.0 2.8e-05 23.8 0.0 2.0 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ORY14420.1 - 7.5e-05 22.7 0.0 0.00014 21.8 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding BppU_IgG PF18667.1 ORY14422.1 - 0.045 13.9 0.0 0.14 12.3 0.0 1.9 2 0 0 2 2 2 0 Baseplate upper protein immunoglobulin like domain SNAP-25 PF00835.19 ORY14422.1 - 0.096 13.0 0.2 0.49 10.7 0.0 2.3 2 0 0 2 2 2 0 SNAP-25 family COPIIcoated_ERV PF07970.12 ORY14423.1 - 4.9e-32 111.6 0.0 7.3e-32 111.0 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 ORY14423.1 - 1.3e-20 73.5 0.0 2.7e-20 72.5 0.0 1.6 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) RTT107_BRCT_5 PF16770.5 ORY14424.1 - 5.2e-05 23.1 0.0 0.00016 21.5 0.0 1.9 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT PF00533.26 ORY14424.1 - 0.00022 21.5 0.0 0.00083 19.7 0.0 2.0 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 ORY14424.1 - 0.0016 18.8 0.1 0.018 15.4 0.0 2.5 3 0 0 3 3 3 1 BRCT domain, a BRCA1 C-terminus domain STE2 PF02116.15 ORY14425.1 - 2.8e-92 309.0 21.8 3.2e-92 308.8 21.8 1.0 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR SelK_SelG PF10961.8 ORY14426.1 - 0.12 13.0 0.0 0.38 11.4 0.0 1.8 1 0 0 1 1 1 0 Selenoprotein SelK_SelG CAP PF00188.26 ORY14427.1 - 4.2e-18 66.4 0.4 6.2e-18 65.8 0.4 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Pkinase PF00069.25 ORY14428.1 - 2.3e-64 217.3 0.0 2.9e-64 217.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY14428.1 - 1.2e-30 106.7 0.0 3.9e-30 105.0 0.0 1.7 1 1 1 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 ORY14428.1 - 0.00021 20.4 0.1 0.00027 20.0 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 ORY14428.1 - 0.012 15.5 0.1 0.082 12.8 0.1 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family FTA2 PF13095.6 ORY14428.1 - 0.02 14.5 0.1 1.5 8.4 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Sugar_tr PF00083.24 ORY14429.1 - 1.1e-93 314.6 12.3 9.2e-93 311.5 12.3 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter GTP_cyclohydro2 PF00925.20 ORY14429.1 - 3e-55 186.3 0.0 6.8e-55 185.1 0.0 1.6 1 1 0 1 1 1 1 GTP cyclohydrolase II MFS_1 PF07690.16 ORY14429.1 - 6.4e-32 110.8 40.2 1e-28 100.3 20.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 ORY14429.1 - 0.00045 18.7 2.1 0.013 13.8 0.1 2.4 1 1 1 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family Reprolysin_3 PF13582.6 ORY14430.1 - 0.14 12.7 0.0 0.27 11.7 0.0 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Metallopep PF12044.8 ORY14430.1 - 0.17 10.5 0.1 0.25 9.9 0.1 1.1 1 0 0 1 1 1 0 Putative peptidase family Lipase_GDSL_2 PF13472.6 ORY14431.1 - 8.6e-06 26.3 0.1 1e-05 26.0 0.1 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Fungal_trans PF04082.18 ORY14434.1 - 1.6e-21 76.6 0.0 2.4e-21 75.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 ORY14434.1 - 6.5e-09 35.8 14.2 0.00043 20.6 2.5 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY14434.1 - 2.8e-06 27.5 7.0 2.8e-06 27.5 7.0 2.9 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORY14434.1 - 0.00013 22.5 13.3 0.021 15.6 2.5 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger DLIC PF05783.11 ORY14434.1 - 0.78 8.5 2.9 1.8 7.3 2.9 1.5 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) HhH-GPD PF00730.25 ORY14437.1 - 5.3e-20 71.9 0.0 7.6e-20 71.4 0.0 1.2 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 ORY14437.1 - 7e-07 28.8 0.0 1.7e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif AAA_11 PF13086.6 ORY14438.1 - 2.6e-60 204.4 0.0 6.3e-60 203.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.6 ORY14438.1 - 4.6e-55 186.4 0.0 3.2e-54 183.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 ORY14438.1 - 4.2e-12 46.2 0.0 1.5e-10 41.1 0.0 2.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 ORY14438.1 - 2.5e-10 40.9 0.0 1.1e-09 38.8 0.0 2.2 2 1 0 2 2 1 1 AAA domain Viral_helicase1 PF01443.18 ORY14438.1 - 4.6e-06 26.5 0.0 1.2 8.8 0.0 3.7 4 0 0 4 4 3 3 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.21 ORY14438.1 - 6.2e-06 25.9 0.1 4.2e-05 23.2 0.0 1.9 1 1 1 2 2 2 1 UvrD/REP helicase N-terminal domain DUF2075 PF09848.9 ORY14438.1 - 6.8e-06 25.6 0.3 3.9e-05 23.0 0.3 2.1 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 ORY14438.1 - 1.3e-05 25.3 0.0 8.4e-05 22.6 0.0 2.3 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit PhoH PF02562.16 ORY14438.1 - 0.00044 19.8 0.0 0.03 13.8 0.0 2.4 2 1 0 2 2 2 1 PhoH-like protein DEAD PF00270.29 ORY14438.1 - 0.00064 19.5 0.3 0.0071 16.1 0.3 2.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_RecD PF05127.14 ORY14438.1 - 0.00065 19.6 0.0 0.029 14.2 0.0 2.7 2 1 0 2 2 2 1 Helicase AAA_22 PF13401.6 ORY14438.1 - 0.0008 19.7 0.2 0.0057 16.9 0.2 2.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ORY14438.1 - 0.00098 19.5 0.0 0.0023 18.3 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain T2SSE PF00437.20 ORY14438.1 - 0.0014 17.7 0.0 0.0028 16.7 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein UvrD_C_2 PF13538.6 ORY14438.1 - 0.0017 18.1 0.0 0.17 11.8 0.0 2.6 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain Flavi_DEAD PF07652.14 ORY14438.1 - 0.0027 17.7 0.1 0.0062 16.5 0.0 1.6 2 0 0 2 2 1 1 Flavivirus DEAD domain UvrD_C PF13361.6 ORY14438.1 - 0.0044 16.4 0.4 17 4.6 0.0 3.3 2 2 1 3 3 3 0 UvrD-like helicase C-terminal domain AAA PF00004.29 ORY14438.1 - 0.01 16.3 0.0 0.029 14.8 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 ORY14438.1 - 0.023 14.4 0.0 0.1 12.3 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 ORY14438.1 - 0.033 14.2 0.1 0.095 12.7 0.1 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 ORY14438.1 - 0.04 13.5 0.1 0.2 11.2 0.0 2.1 2 1 0 3 3 3 0 AAA domain Rad17 PF03215.15 ORY14438.1 - 0.067 13.1 0.2 4.8 7.1 0.1 2.6 2 1 1 3 3 2 0 Rad17 P-loop domain TrwB_AAD_bind PF10412.9 ORY14438.1 - 0.069 12.0 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_33 PF13671.6 ORY14438.1 - 0.098 12.8 0.0 0.31 11.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 ORY14438.1 - 0.1 12.0 0.2 2.4 7.4 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family IstB_IS21 PF01695.17 ORY14438.1 - 0.1 12.3 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein ABC_tran PF00005.27 ORY14438.1 - 0.1 13.1 0.0 0.28 11.7 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_23 PF13476.6 ORY14438.1 - 0.14 12.6 5.7 1.1 9.7 0.0 2.7 2 1 1 3 3 2 0 AAA domain 4HB_MCP_1 PF12729.7 ORY14438.1 - 5.3 6.6 6.2 0.36 10.4 0.7 1.7 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction DUF1244 PF06844.11 ORY14440.1 - 0.49 10.6 2.1 1.2 9.3 2.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1244) CLZ PF16526.5 ORY14441.1 - 0.012 16.0 1.2 3.8 7.9 0.1 2.6 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Amino_oxidase PF01593.24 ORY14442.1 - 9.8e-51 173.4 0.4 8.2e-50 170.4 0.4 2.1 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 ORY14442.1 - 1.3e-14 54.1 0.2 3.5e-14 52.8 0.2 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ORY14442.1 - 9.2e-07 28.4 0.4 1.2e-05 24.7 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ORY14442.1 - 2.4e-05 24.1 2.1 0.00011 22.0 2.0 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 ORY14442.1 - 3.9e-05 22.5 0.3 7e-05 21.7 0.3 1.3 1 0 0 1 1 1 1 HI0933-like protein AlaDh_PNT_C PF01262.21 ORY14442.1 - 5.9e-05 22.5 0.0 9.2e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 ORY14442.1 - 9.2e-05 21.8 0.7 0.00016 21.1 0.7 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 ORY14442.1 - 0.0001 21.6 0.2 0.00017 20.8 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 ORY14442.1 - 0.00014 22.3 0.3 0.00038 20.9 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ORY14442.1 - 0.001 19.1 0.2 0.24 11.4 0.0 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.17 ORY14442.1 - 0.001 18.4 0.2 0.0017 17.6 0.2 1.3 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 ORY14442.1 - 0.0034 16.8 0.0 0.005 16.3 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 ORY14442.1 - 0.0053 15.9 1.8 0.0095 15.1 1.8 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 ORY14442.1 - 0.048 12.9 0.7 0.092 12.0 0.7 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 ORY14442.1 - 0.072 13.0 0.3 0.13 12.1 0.3 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 ORY14442.1 - 0.11 13.0 0.0 0.19 12.2 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Lycopene_cycl PF05834.12 ORY14442.1 - 0.22 10.5 0.6 0.33 9.9 0.6 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein TMEM171 PF15471.6 ORY14445.1 - 1.5 7.7 3.4 1.8 7.5 3.4 1.1 1 0 0 1 1 1 0 Transmembrane protein family 171 Actin PF00022.19 ORY14447.1 - 1.1e-112 376.6 0.0 7.6e-112 373.9 0.0 1.8 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 ORY14447.1 - 0.016 14.1 0.0 0.061 12.1 0.0 1.8 1 1 0 1 1 1 0 MreB/Mbl protein Ribosomal_L5e PF17144.4 ORY14448.1 - 9.9e-80 266.3 0.3 1.7e-79 265.5 0.3 1.4 1 0 0 1 1 1 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 ORY14448.1 - 9.6e-36 122.6 10.4 9.6e-36 122.6 10.4 1.9 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Thr_synth_N PF14821.6 ORY14448.1 - 0.017 15.4 0.2 0.34 11.2 0.0 2.6 3 0 0 3 3 3 0 Threonine synthase N terminus Ribosomal_L18p PF00861.22 ORY14448.1 - 0.092 13.1 2.4 0.21 11.9 0.0 2.2 2 0 0 2 2 2 0 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast UvrD-helicase PF00580.21 ORY14448.1 - 0.13 11.8 3.7 0.24 10.9 3.7 1.4 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain DUF3135 PF11333.8 ORY14449.1 - 0.1 12.8 0.0 2.5 8.4 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3135) TFIIA PF03153.13 ORY14449.1 - 3.1 7.7 11.2 0.67 9.9 7.6 1.7 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Pcc1 PF09341.10 ORY14451.1 - 8.8e-32 109.1 0.2 1.1e-31 108.8 0.2 1.1 1 0 0 1 1 1 1 Transcription factor Pcc1 CCDC14 PF15254.6 ORY14452.1 - 0.064 11.9 1.0 0.083 11.5 1.0 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 14 DUF676 PF05057.14 ORY14453.1 - 6e-52 176.3 0.0 1.1e-51 175.5 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 ORY14453.1 - 5.5e-06 27.2 0.0 1.2e-05 26.1 0.0 1.5 1 1 1 2 2 2 1 Alpha/beta hydrolase family PGAP1 PF07819.13 ORY14453.1 - 0.0051 16.6 0.0 0.012 15.3 0.0 1.6 1 1 0 1 1 1 1 PGAP1-like protein Lipase_3 PF01764.25 ORY14453.1 - 0.037 13.9 0.0 0.067 13.0 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Palm_thioest PF02089.15 ORY14453.1 - 0.038 13.8 0.0 0.054 13.3 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.20 ORY14453.1 - 0.089 12.4 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF2048 PF09752.9 ORY14453.1 - 0.11 11.5 0.1 0.18 10.8 0.1 1.2 1 0 0 1 1 1 0 Abhydrolase domain containing 18 Thioesterase PF00975.20 ORY14453.1 - 0.12 12.5 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain Lipase_2 PF01674.18 ORY14453.1 - 0.15 11.6 0.0 0.31 10.5 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 2) APH PF01636.23 ORY14454.1 - 5e-10 39.7 0.2 1.5e-08 34.8 0.0 2.8 2 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 ORY14454.1 - 1.2e-07 31.3 0.0 0.0002 20.8 0.0 3.1 3 0 0 3 3 3 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 ORY14454.1 - 4.7e-06 26.1 0.0 2e-05 24.1 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY14454.1 - 0.00076 18.8 0.0 0.002 17.5 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 ORY14454.1 - 0.0012 18.4 0.0 1.6 8.3 0.0 2.4 1 1 1 2 2 2 2 RIO1 family Choline_kinase PF01633.20 ORY14454.1 - 0.0086 15.7 0.0 0.012 15.2 0.0 1.1 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.20 ORY14454.1 - 0.09 12.1 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase CorA PF01544.18 ORY14455.1 - 1.5e-06 27.8 0.9 2.4e-06 27.1 0.9 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein CpeS PF09367.10 ORY14455.1 - 0.16 11.8 0.1 0.27 11.1 0.1 1.3 1 0 0 1 1 1 0 CpeS-like protein GCS PF03074.16 ORY14460.1 - 1.8e-174 580.4 0.0 2.2e-174 580.1 0.0 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase GATA PF00320.27 ORY14462.1 - 2.8e-15 55.6 5.3 6.5e-15 54.5 5.3 1.6 1 0 0 1 1 1 1 GATA zinc finger zinc_ribbon_9 PF14369.6 ORY14462.1 - 0.47 10.7 1.6 0.95 9.8 1.6 1.4 1 0 0 1 1 1 0 zinc-ribbon CaM_bdg_C0 PF10562.9 ORY14463.1 - 0.19 11.8 0.2 0.19 11.8 0.2 1.7 2 0 0 2 2 2 0 Calmodulin-binding domain C0 of NMDA receptor NR1 subunit DUF2014 PF09427.10 ORY14466.1 - 1.2e-100 336.3 7.0 1.6e-100 335.8 7.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2014) HLH PF00010.26 ORY14466.1 - 4.4e-17 61.8 0.1 1.1e-16 60.5 0.1 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain bZIP_1 PF00170.21 ORY14466.1 - 0.17 12.0 0.9 0.5 10.5 0.9 1.8 1 0 0 1 1 1 0 bZIP transcription factor HAD_2 PF13419.6 ORY14467.1 - 7.6e-05 22.9 0.0 0.00012 22.2 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ORY14467.1 - 0.012 15.6 0.2 0.033 14.3 0.2 1.7 1 0 0 1 1 1 0 HAD-hyrolase-like CARD_2 PF16739.5 ORY14467.1 - 0.13 12.3 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 Caspase recruitment domain Arrestin_N PF00339.29 ORY14468.1 - 1e-09 38.6 0.5 2.5e-07 30.9 0.0 3.2 3 0 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 ORY14468.1 - 0.018 15.5 0.9 0.091 13.2 0.0 2.3 2 1 0 2 2 2 0 Arrestin (or S-antigen), C-terminal domain Alpha-amylase PF00128.24 ORY14470.1 - 2e-23 83.5 0.0 4.2e-23 82.4 0.0 1.5 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Pirin PF02678.16 ORY14492.1 - 7.7e-30 103.1 0.0 1.4e-29 102.3 0.0 1.4 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 ORY14492.1 - 5.1e-25 87.8 0.0 1.7e-23 82.9 0.0 2.2 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.11 ORY14492.1 - 8.3e-07 28.6 3.5 8e-06 25.5 1.2 2.6 3 0 0 3 3 3 1 Cupin domain MCRA PF06100.11 ORY14493.1 - 1.2e-211 703.9 0.0 1.3e-211 703.7 0.0 1.0 1 0 0 1 1 1 1 MCRA family NAD_binding_8 PF13450.6 ORY14493.1 - 0.00044 20.4 0.5 0.00092 19.4 0.5 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ORY14493.1 - 0.0037 16.9 0.1 0.059 12.9 0.1 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 ORY14493.1 - 0.063 13.8 0.1 0.51 10.9 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ORY14493.1 - 0.065 12.5 0.0 5.9 6.0 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Mito_carr PF00153.27 ORY14496.1 - 3.2e-20 71.9 4.7 2.4e-08 33.8 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Colicin_V PF02674.16 ORY14496.1 - 0.0053 16.7 0.4 0.018 15.0 0.0 2.1 2 1 0 2 2 2 1 Colicin V production protein Mobilization_B PF17511.2 ORY14496.1 - 0.039 14.3 0.0 0.1 13.0 0.0 1.6 2 0 0 2 2 2 0 Mobilization protein B zf-C2H2 PF00096.26 ORY14497.1 - 1.2e-05 25.5 21.1 0.00062 20.1 0.4 5.0 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_3rep PF18868.1 ORY14497.1 - 0.00019 22.1 2.9 0.00027 21.6 0.1 2.6 3 0 0 3 3 3 1 Zinc finger C2H2-type, 3 repeats zf-Di19 PF05605.12 ORY14497.1 - 0.00064 20.0 1.3 0.00064 20.0 1.3 2.9 3 0 0 3 3 3 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 ORY14497.1 - 0.0012 19.5 4.4 0.0088 16.8 0.4 5.2 5 1 0 5 5 5 2 C2H2-type zinc finger zf-C2H2_8 PF15909.5 ORY14497.1 - 0.0052 17.1 0.4 0.016 15.5 0.4 1.8 1 0 0 1 1 1 1 C2H2-type zinc ribbon Elf1 PF05129.13 ORY14497.1 - 0.036 14.1 17.6 0.03 14.4 2.1 3.7 2 1 2 4 4 4 0 Transcription elongation factor Elf1 like zf-H2C2_2 PF13465.6 ORY14497.1 - 0.064 13.7 18.3 1.8 9.2 0.5 4.6 4 0 0 4 4 4 0 Zinc-finger double domain FYVE PF01363.21 ORY14497.1 - 2.8 8.1 15.3 0.86 9.8 0.9 3.1 2 1 0 2 2 2 0 FYVE zinc finger EHN PF06441.12 ORY14498.1 - 1.2e-36 125.3 0.1 1.8e-36 124.8 0.1 1.3 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 ORY14498.1 - 2.3e-06 27.4 0.5 5e-06 26.3 0.5 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Oxidored_FMN PF00724.20 ORY14500.1 - 3.3e-36 125.2 0.0 4.4e-36 124.8 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family ADH_N_2 PF16884.5 ORY14501.1 - 1.5e-29 102.0 0.0 3.5e-29 100.9 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 ORY14501.1 - 9.7e-21 74.1 0.0 1.6e-20 73.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ORY14501.1 - 1.1e-09 39.5 0.0 2.8e-09 38.1 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase rRNA_processing PF08524.11 ORY14503.1 - 0.02 14.9 0.4 0.02 14.9 0.4 2.1 2 0 0 2 2 2 0 rRNA processing DUF3035 PF11233.8 ORY14503.1 - 0.094 13.0 3.4 2 8.7 3.4 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3035) SPX PF03105.19 ORY14503.1 - 7 6.5 21.2 9 6.1 21.2 1.1 1 0 0 1 1 1 0 SPX domain D-ser_dehydrat PF14031.6 ORY14506.1 - 0.0028 18.3 0.4 0.003 18.2 0.4 1.1 1 0 0 1 1 1 1 Putative serine dehydratase domain zf-NADH-PPase PF09297.11 ORY14506.1 - 0.64 9.7 7.7 4.8 6.9 0.2 2.4 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain RNA_pol_Rpb5_N PF03871.14 ORY14507.1 - 0.13 12.9 0.1 0.22 12.1 0.1 1.4 1 0 0 1 1 1 0 RNA polymerase Rpb5, N-terminal domain PI-PLC-X PF00388.19 ORY14508.1 - 6.5e-63 210.6 0.0 9.7e-63 210.1 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 ORY14508.1 - 9.3e-43 145.2 0.0 1.9e-42 144.3 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 ORY14508.1 - 1.8e-05 24.9 0.0 5e-05 23.5 0.0 1.8 1 0 0 1 1 1 1 C2 domain Cupin_2 PF07883.11 ORY14509.1 - 0.0022 17.6 0.1 0.0026 17.4 0.1 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_7 PF12973.7 ORY14509.1 - 0.014 15.3 0.0 0.028 14.3 0.0 1.5 1 1 0 1 1 1 0 ChrR Cupin-like domain Cupin_1 PF00190.22 ORY14509.1 - 0.14 11.7 0.0 0.2 11.3 0.0 1.3 1 1 0 1 1 1 0 Cupin RNA_pol_Rbc25 PF08292.12 ORY14511.1 - 4.2e-30 104.6 0.8 1.4e-29 102.9 0.8 1.8 1 1 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 ORY14511.1 - 5.1e-16 58.8 0.0 2.4e-15 56.6 0.0 2.0 2 0 0 2 2 2 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 NUFIP1 PF10453.9 ORY14512.1 - 2.3e-10 40.2 0.5 1.1e-09 38.0 0.5 2.2 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-CCCH PF00642.24 ORY14512.1 - 1.4e-05 24.9 3.4 2.2e-05 24.2 3.4 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 ORY14512.1 - 0.00036 20.5 8.6 0.0006 19.8 8.6 1.4 1 0 0 1 1 1 1 Zinc finger domain DUF2188 PF09954.9 ORY14512.1 - 0.026 14.7 1.2 0.1 12.7 1.2 2.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2188) zf-CCCH_4 PF18044.1 ORY14512.1 - 0.32 10.8 3.9 0.56 10.1 3.9 1.3 1 0 0 1 1 1 0 CCCH-type zinc finger Pkinase PF00069.25 ORY14513.1 - 1.9e-27 96.3 0.7 1.3e-20 73.9 0.0 2.8 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORY14513.1 - 1.8e-14 53.7 0.1 6.6e-14 51.8 0.1 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 ORY14513.1 - 0.065 12.6 0.5 0.16 11.3 0.1 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family AAA_2 PF07724.14 ORY14514.1 - 0.00025 21.2 0.0 0.00038 20.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) PBP_dimer PF03717.15 ORY14514.1 - 0.045 14.1 0.0 4.9 7.5 0.0 2.3 2 0 0 2 2 2 0 Penicillin-binding Protein dimerisation domain Bac_luciferase PF00296.20 ORY14516.1 - 3.8e-48 164.5 0.2 8.6e-48 163.4 0.2 1.5 1 1 0 1 1 1 1 Luciferase-like monooxygenase ADH_N PF08240.12 ORY14517.1 - 0.015 15.2 0.0 0.033 14.0 0.0 1.6 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORY14517.1 - 0.069 13.1 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase MFS_1 PF07690.16 ORY14518.1 - 2.9e-07 29.7 33.5 2.9e-07 29.7 33.5 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 ORY14518.1 - 2.8e-05 23.9 4.5 2.8e-05 23.9 4.5 1.9 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 FMO-like PF00743.19 ORY14519.1 - 8.5e-14 50.9 0.0 2.3e-13 49.4 0.0 1.6 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 ORY14519.1 - 7.3e-10 38.9 0.0 2.7e-09 37.1 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ORY14519.1 - 2.8e-09 36.6 0.0 3e-08 33.3 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ORY14519.1 - 9.9e-07 28.2 0.0 0.00014 21.2 0.0 2.5 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 ORY14519.1 - 1.4e-05 24.5 0.0 0.00017 21.0 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ORY14519.1 - 9.3e-05 22.2 0.2 0.0024 17.5 0.2 2.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 ORY14519.1 - 0.00065 19.7 0.1 0.95 9.4 0.0 3.5 3 1 1 4 4 4 2 FAD-NAD(P)-binding Thi4 PF01946.17 ORY14519.1 - 0.0079 15.5 0.0 0.055 12.7 0.0 2.0 2 0 0 2 2 2 1 Thi4 family MFS_1 PF07690.16 ORY14520.1 - 8.8e-20 70.9 30.0 1.4e-19 70.3 30.0 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Bac_luciferase PF00296.20 ORY14521.1 - 2e-60 204.9 0.0 2.7e-60 204.4 0.0 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase Amidohydro_2 PF04909.14 ORY14521.1 - 0.071 12.9 0.0 0.19 11.5 0.0 1.6 2 0 0 2 2 2 0 Amidohydrolase Ribul_P_3_epim PF00834.19 ORY14522.1 - 1.1e-62 210.9 0.0 8.2e-62 208.1 0.0 1.9 1 1 0 1 1 1 1 Ribulose-phosphate 3 epimerase family QRPTase_C PF01729.19 ORY14522.1 - 0.013 15.2 0.0 0.022 14.6 0.0 1.4 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain OMPdecase PF00215.24 ORY14522.1 - 0.016 14.8 0.2 0.029 14.0 0.2 1.5 1 1 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family His_biosynth PF00977.21 ORY14522.1 - 0.12 11.8 0.0 0.43 10.0 0.0 1.8 2 0 0 2 2 2 0 Histidine biosynthesis protein Methyltransf_11 PF08241.12 ORY14523.1 - 4.2e-07 30.5 0.0 9e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY14523.1 - 0.00013 21.8 0.0 0.00027 20.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY14523.1 - 0.016 15.9 0.0 0.044 14.5 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain LSM PF01423.22 ORY14524.1 - 1.2e-15 57.0 0.2 1.7e-15 56.5 0.2 1.2 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 ORY14524.1 - 0.019 14.6 0.0 0.029 14.0 0.0 1.3 1 0 0 1 1 1 0 Hfq protein DUF2469 PF10611.9 ORY14524.1 - 0.12 12.9 0.1 0.16 12.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2469) ATP_synt_H PF05493.13 ORY14526.1 - 0.14 12.7 1.0 0.19 12.2 0.3 1.6 2 0 0 2 2 2 0 ATP synthase subunit H DUF4010 PF13194.6 ORY14532.1 - 0.025 14.3 1.8 0.025 14.3 1.8 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4010) HET PF06985.11 ORY14533.1 - 4e-33 114.8 0.0 1.3e-32 113.2 0.0 1.9 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HrpJ PF07201.11 ORY14533.1 - 0.04 14.2 0.5 0.073 13.4 0.5 1.3 1 0 0 1 1 1 0 HrpJ-like domain Glyco_hyd_65N_2 PF14498.6 ORY14534.1 - 1.8e-58 198.2 0.3 2.6e-58 197.7 0.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain DRMBL PF07522.14 ORY14536.1 - 1.1e-34 118.9 0.0 2.3e-34 117.9 0.0 1.5 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 ORY14536.1 - 7.1e-07 28.9 0.0 1.4e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Fib_alpha PF08702.10 ORY14537.1 - 0.14 12.4 0.3 0.22 11.7 0.3 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Beta_elim_lyase PF01212.21 ORY14540.1 - 9.1e-75 251.6 0.0 1.1e-74 251.3 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 ORY14540.1 - 6.6e-05 21.6 0.0 0.00012 20.8 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 ORY14540.1 - 0.00047 19.4 0.0 0.00062 19.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 ORY14540.1 - 0.0094 15.3 0.4 0.026 13.9 0.4 1.8 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family OKR_DC_1 PF01276.20 ORY14540.1 - 0.012 14.4 0.0 0.016 14.0 0.0 1.2 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Glyco_hydro_76 PF03663.14 ORY14542.1 - 1.8e-120 402.8 18.2 2.1e-120 402.6 18.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 DUF4271 PF14093.6 ORY14544.1 - 1.1 9.1 7.1 0.19 11.6 0.2 2.5 2 1 0 3 3 3 0 Domain of unknown function (DUF4271) Cu-oxidase_3 PF07732.15 ORY14545.1 - 9.7e-22 77.2 0.9 1.8e-21 76.4 0.2 1.8 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 ORY14545.1 - 1.9e-19 69.7 2.3 3.2e-17 62.5 0.3 2.4 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.22 ORY14545.1 - 6.7e-05 23.1 0.0 0.00096 19.3 0.0 2.5 2 0 0 2 2 2 1 Multicopper oxidase FIT1_2 PF17357.2 ORY14546.1 - 0.6 10.2 6.6 2 8.6 6.6 1.9 1 1 0 1 1 1 0 Facilitor Of iron transport 1 and 2 Sigma54_activat PF00158.26 ORY14547.1 - 0.11 12.2 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain Fungal_trans PF04082.18 ORY14548.1 - 1.3e-16 60.5 0.0 2.4e-16 59.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY14548.1 - 2.3e-06 27.6 11.0 3.7e-06 27.0 11.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HSBP1 PF06825.12 ORY14548.1 - 0.065 13.1 0.1 0.22 11.4 0.1 1.9 1 0 0 1 1 1 0 Heat shock factor binding protein 1 2OG-FeII_Oxy_2 PF13532.6 ORY14549.1 - 8.7e-29 101.1 0.0 1.2e-28 100.6 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DAO PF01266.24 ORY14550.1 - 1.1e-39 137.0 0.0 1.3e-39 136.8 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 ORY14550.1 - 2.7e-05 24.2 0.2 0.0094 15.9 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 ORY14550.1 - 0.00031 20.1 0.1 0.046 13.0 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORY14550.1 - 0.00065 19.9 0.0 0.0021 18.3 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ORY14550.1 - 0.00084 18.7 0.2 0.02 14.1 0.2 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 ORY14550.1 - 0.0033 16.7 0.0 0.0061 15.8 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Amino_oxidase PF01593.24 ORY14550.1 - 0.0062 15.9 0.0 0.24 10.7 0.0 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.12 ORY14550.1 - 0.012 14.7 0.0 0.041 12.9 0.1 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_binding_2 PF00890.24 ORY14550.1 - 0.016 14.3 0.7 0.24 10.4 0.5 2.2 1 1 0 2 2 2 0 FAD binding domain Trp_halogenase PF04820.14 ORY14550.1 - 0.018 13.9 0.0 0.035 13.0 0.0 1.5 2 0 0 2 2 2 0 Tryptophan halogenase HI0933_like PF03486.14 ORY14550.1 - 0.027 13.2 0.1 2.7 6.6 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein MCRA PF06100.11 ORY14550.1 - 0.11 11.2 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 MCRA family GIDA PF01134.22 ORY14550.1 - 0.11 11.5 0.5 2 7.4 0.1 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A ADH_zinc_N PF00107.26 ORY14551.1 - 1.3e-08 34.9 0.6 3.7e-08 33.4 0.3 1.8 3 0 0 3 3 3 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 ORY14551.1 - 0.003 16.9 1.1 0.0059 15.9 1.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Semialdhyde_dh PF01118.24 ORY14551.1 - 0.0036 17.7 0.3 0.012 16.0 0.2 2.0 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain ADH_N PF08240.12 ORY14551.1 - 0.056 13.3 0.0 0.44 10.4 0.0 2.2 1 1 1 2 2 2 0 Alcohol dehydrogenase GroES-like domain DapB_N PF01113.20 ORY14551.1 - 0.08 13.1 0.1 0.17 12.0 0.1 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus ADH_zinc_N PF00107.26 ORY14552.1 - 2.1e-08 34.2 0.0 3.9e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ORY14552.1 - 4.1e-07 29.9 0.0 9.4e-07 28.7 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain SKG6 PF08693.10 ORY14552.1 - 0.014 14.8 1.7 0.026 13.9 1.7 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain ADH_zinc_N_2 PF13602.6 ORY14552.1 - 0.027 15.5 0.0 0.058 14.5 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Mucin15 PF15672.5 ORY14552.1 - 0.071 12.6 5.2 0.14 11.6 5.2 1.4 1 0 0 1 1 1 0 Cell-membrane associated Mucin15 EphA2_TM PF14575.6 ORY14552.1 - 0.091 13.6 0.0 0.24 12.3 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Syndecan PF01034.20 ORY14552.1 - 0.13 12.1 1.2 0.29 11.1 1.2 1.5 1 0 0 1 1 1 0 Syndecan domain LANC_like PF05147.13 ORY14553.1 - 3.1e-30 104.9 0.0 1.3e-29 102.9 0.0 1.8 1 1 0 2 2 2 1 Lanthionine synthetase C-like protein Tyrosinase PF00264.20 ORY14554.1 - 5.1e-44 151.2 0.6 8.4e-44 150.5 0.6 1.4 1 0 0 1 1 1 1 Common central domain of tyrosinase Tyosinase_C PF18132.1 ORY14554.1 - 1.6e-14 54.6 0.0 2.7e-14 53.9 0.0 1.4 1 0 0 1 1 1 1 Tyosinase C-terminal domain Methyltransf_25 PF13649.6 ORY14555.1 - 3e-16 59.9 0.0 4.2e-16 59.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY14555.1 - 4.7e-13 49.6 0.0 7e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY14555.1 - 6.7e-13 48.7 0.0 9.5e-13 48.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY14555.1 - 2.9e-11 44.0 0.0 4.4e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY14555.1 - 2.8e-10 40.3 0.0 3.9e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 ORY14555.1 - 9.6e-05 21.8 0.0 0.00013 21.3 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase domain CheR PF01739.18 ORY14555.1 - 0.00032 20.2 0.0 0.34 10.4 0.0 2.3 1 1 1 2 2 2 2 CheR methyltransferase, SAM binding domain MTS PF05175.14 ORY14555.1 - 0.0004 20.0 0.0 0.00058 19.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain NodS PF05401.11 ORY14555.1 - 0.0012 18.5 0.0 0.0018 17.9 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_32 PF13679.6 ORY14555.1 - 0.06 13.3 0.0 0.087 12.8 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_5 PF01795.19 ORY14555.1 - 0.093 12.2 0.0 0.13 11.8 0.0 1.1 1 0 0 1 1 1 0 MraW methylase family Methyltransf_4 PF02390.17 ORY14555.1 - 0.18 11.2 0.0 0.84 9.1 0.0 1.8 2 0 0 2 2 2 0 Putative methyltransferase RhoGAP PF00620.27 ORY14557.1 - 9e-36 123.0 0.6 2.3e-35 121.7 0.4 1.8 2 0 0 2 2 2 1 RhoGAP domain LIM PF00412.22 ORY14557.1 - 1.1e-23 83.2 36.5 3.6e-11 43.1 5.3 5.2 5 0 0 5 5 5 4 LIM domain T2SSE PF00437.20 ORY14557.1 - 0.029 13.4 0.1 0.049 12.7 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein RNA_pol_Rpb4 PF03874.16 ORY14558.1 - 3.7e-23 82.2 0.0 4.8e-23 81.8 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 Astacin PF01400.24 ORY14559.1 - 3.9e-08 33.1 0.0 6.5e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.24 ORY14559.1 - 0.0029 17.4 0.0 0.0035 17.2 0.0 1.3 1 0 0 1 1 1 1 Matrixin Phosphodiest PF01663.22 ORY14559.1 - 0.0077 15.8 0.1 0.01 15.4 0.1 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Reprolysin_5 PF13688.6 ORY14559.1 - 0.02 15.0 0.0 0.033 14.3 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 ORY14559.1 - 0.13 12.8 0.0 0.22 12.0 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M57 PF12388.8 ORY14559.1 - 0.13 11.8 0.2 0.71 9.4 0.2 1.9 1 1 1 2 2 2 0 Dual-action HEIGH metallo-peptidase Reprolysin_4 PF13583.6 ORY14559.1 - 0.25 11.0 1.1 0.45 10.1 0.8 1.5 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like SET PF00856.28 ORY14562.1 - 1.4e-17 64.6 0.2 3.6e-16 60.0 0.0 2.8 2 1 0 2 2 2 1 SET domain HAUS6_N PF14661.6 ORY14562.1 - 0.24 11.0 0.3 0.44 10.1 0.3 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus RRM_1 PF00076.22 ORY14563.1 - 2.9e-12 46.2 0.0 2.5e-10 40.0 0.0 2.9 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sds3 PF08598.11 ORY14565.1 - 6.7e-19 68.8 0.1 6.7e-19 68.8 0.1 2.2 2 1 0 2 2 2 1 Sds3-like DUF1487 PF07368.11 ORY14565.1 - 0.0014 18.1 0.4 0.0041 16.6 0.2 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF1487) DUF4094 PF13334.6 ORY14565.1 - 0.2 12.1 2.6 0.27 11.7 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) SecA_DEAD PF07517.14 ORY14565.1 - 3.3 6.9 7.2 0.14 11.4 1.3 1.6 2 0 0 2 2 2 0 SecA DEAD-like domain DUF676 PF05057.14 ORY14566.1 - 0.0031 17.0 0.0 0.005 16.4 0.0 1.3 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 ORY14566.1 - 0.074 13.6 0.1 0.11 13.0 0.1 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family Tannase PF07519.11 ORY14570.1 - 5.9e-110 368.4 0.0 7.7e-110 368.0 0.0 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase HET PF06985.11 ORY14571.1 - 9e-28 97.5 0.6 9.9e-28 97.3 0.6 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Pkinase PF00069.25 ORY14572.1 - 6.5e-34 117.5 0.0 1.4e-22 80.3 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORY14572.1 - 1.8e-25 89.7 0.0 3e-25 89.0 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 ORY14572.1 - 0.069 12.7 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 ORY14572.1 - 0.11 11.8 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CK2S PF15011.6 ORY14575.1 - 0.0021 18.0 1.4 0.0032 17.4 1.4 1.3 1 1 0 1 1 1 1 Casein Kinase 2 substrate DUF445 PF04286.12 ORY14575.1 - 0.013 15.3 0.6 0.014 15.2 0.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Vps53_N PF04100.12 ORY14575.1 - 0.019 13.9 0.6 0.022 13.7 0.6 1.1 1 0 0 1 1 1 0 Vps53-like, N-terminal PEPcase PF00311.17 ORY14575.1 - 0.032 12.3 0.7 0.034 12.2 0.7 1.0 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxylase Plk4_PB2 PF18409.1 ORY14575.1 - 0.26 12.0 2.0 3.6 8.3 0.4 2.3 1 1 1 2 2 2 0 Polo-like Kinase 4 Polo Box 2 CorA PF01544.18 ORY14575.1 - 0.29 10.4 1.6 0.36 10.1 1.6 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Cys_Met_Meta_PP PF01053.20 ORY14576.1 - 2e-141 471.0 0.1 2.2e-141 470.8 0.1 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 ORY14576.1 - 2e-09 37.1 0.1 3e-09 36.5 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 ORY14576.1 - 4.3e-06 26.3 0.1 7.8e-06 25.4 0.1 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 ORY14576.1 - 6e-06 25.5 0.2 1.2e-05 24.5 0.2 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 ORY14576.1 - 0.032 13.5 0.0 0.072 12.4 0.0 1.5 1 0 0 1 1 1 0 Beta-eliminating lyase Crinivirus_P26 PF07416.11 ORY14576.1 - 0.2 11.3 0.0 0.38 10.4 0.0 1.4 1 0 0 1 1 1 0 Crinivirus P26 protein Atg14 PF10186.9 ORY14577.1 - 2.5e-72 243.7 0.0 3.2e-72 243.3 0.0 1.1 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 WEMBL PF05701.11 ORY14577.1 - 0.017 13.8 7.6 0.025 13.3 7.6 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light FAM76 PF16046.5 ORY14577.1 - 0.11 11.9 6.5 0.16 11.3 6.5 1.2 1 0 0 1 1 1 0 FAM76 protein DUF1664 PF07889.12 ORY14577.1 - 0.3 11.1 1.8 0.57 10.2 1.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF2959 PF11172.8 ORY14578.1 - 0.02 15.0 4.1 0.23 11.6 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2959) Peptidase_C11 PF03415.14 ORY14578.1 - 0.045 13.2 0.1 0.055 12.9 0.1 1.1 1 0 0 1 1 1 0 Clostripain family DDE_Tnp_ISL3 PF01610.17 ORY14578.1 - 0.077 12.7 2.0 0.1 12.3 2.0 1.1 1 0 0 1 1 1 0 Transposase Pyr_redox_2 PF07992.14 ORY14579.1 - 2.1e-47 161.8 1.6 2.6e-47 161.5 1.6 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ORY14579.1 - 4.8e-20 72.0 1.0 7.6e-17 61.5 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORY14579.1 - 2.2e-16 60.2 1.1 2.9e-14 53.4 0.2 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 ORY14579.1 - 4.6e-07 29.3 0.6 0.00018 20.8 0.1 2.9 2 1 1 3 3 3 2 Thi4 family FAD_oxidored PF12831.7 ORY14579.1 - 2.3e-05 23.9 0.1 2.3e-05 23.9 0.1 2.4 2 1 1 3 3 3 1 FAD dependent oxidoreductase DAO PF01266.24 ORY14579.1 - 0.00011 22.0 2.6 2.1 7.9 1.0 3.4 3 1 0 3 3 3 2 FAD dependent oxidoreductase GIDA PF01134.22 ORY14579.1 - 0.00017 20.8 5.8 0.0034 16.5 0.3 3.7 3 2 1 4 4 4 1 Glucose inhibited division protein A K_oxygenase PF13434.6 ORY14579.1 - 0.00021 20.5 0.5 0.038 13.1 0.0 3.1 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 ORY14579.1 - 0.00047 20.3 0.1 0.093 13.0 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 ORY14579.1 - 0.0013 17.5 1.7 0.026 13.2 0.3 2.9 2 1 1 3 3 3 1 HI0933-like protein NAD_binding_7 PF13241.6 ORY14579.1 - 0.0054 17.1 1.5 0.098 13.1 0.1 2.9 3 1 0 3 3 3 1 Putative NAD(P)-binding FAD_binding_2 PF00890.24 ORY14579.1 - 0.0079 15.3 9.0 0.021 13.9 1.7 3.3 2 1 0 3 3 3 1 FAD binding domain Trp_halogenase PF04820.14 ORY14579.1 - 0.043 12.6 0.3 0.82 8.4 0.1 2.5 3 0 0 3 3 3 0 Tryptophan halogenase ApbA PF02558.16 ORY14579.1 - 0.057 13.1 0.6 0.15 11.7 0.1 1.9 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.20 ORY14579.1 - 0.073 13.1 0.1 6.6 6.8 0.0 3.1 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase WD40 PF00400.32 ORY14580.1 - 4.7e-05 24.1 2.5 0.13 13.1 0.1 3.9 4 0 0 4 4 4 2 WD domain, G-beta repeat CPSF_A PF03178.15 ORY14580.1 - 0.0029 17.0 0.0 0.0055 16.1 0.0 1.6 1 0 0 1 1 1 1 CPSF A subunit region Ribosomal_L10 PF00466.20 ORY14581.1 - 6e-24 84.1 0.0 3.5e-23 81.6 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein L10 RL10P_insert PF17777.1 ORY14581.1 - 3.5e-22 78.2 0.2 8.2e-22 77.0 0.1 1.7 2 0 0 2 2 2 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_60s PF00428.19 ORY14581.1 - 4.9e-22 78.3 3.4 4.9e-22 78.3 3.4 2.0 2 0 0 2 2 2 1 60s Acidic ribosomal protein FR47 PF08445.10 ORY14582.1 - 3.2e-08 33.4 0.0 4.9e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_1 PF00583.25 ORY14582.1 - 0.032 14.5 0.0 0.12 12.6 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family Acetyltransf_CG PF14542.6 ORY14582.1 - 0.053 13.7 0.0 0.31 11.2 0.0 2.1 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.7 ORY14582.1 - 0.067 13.9 0.0 0.12 13.0 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ORY14582.1 - 0.12 12.8 0.0 0.22 12.0 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain p450 PF00067.22 ORY14583.1 - 2.1e-69 234.4 0.0 2.5e-69 234.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 eIF-3_zeta PF05091.12 ORY14584.1 - 4.7e-208 692.4 0.0 5.8e-208 692.1 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF569 PF04601.13 ORY14584.1 - 0.1 12.3 0.0 0.32 10.7 0.0 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF569) Phosphodiest PF01663.22 ORY14586.1 - 1.8e-92 310.7 0.3 2.2e-92 310.4 0.3 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 ORY14586.1 - 0.0031 17.0 0.0 0.16 11.3 0.0 2.3 2 0 0 2 2 2 2 Sulfatase Metalloenzyme PF01676.18 ORY14586.1 - 0.028 13.8 0.1 0.05 12.9 0.1 1.3 1 0 0 1 1 1 0 Metalloenzyme superfamily DUF3827 PF12877.7 ORY14586.1 - 0.077 11.4 0.0 0.12 10.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) NACHT PF05729.12 ORY14588.1 - 9.3e-08 32.2 0.0 2.6e-07 30.7 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 ORY14588.1 - 4.3e-05 23.9 0.1 0.00053 20.4 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 ORY14588.1 - 0.011 16.2 0.7 0.064 13.8 0.0 2.6 3 0 0 3 3 3 0 AAA domain ABC_tran PF00005.27 ORY14588.1 - 0.012 16.1 0.4 0.06 13.9 0.0 2.1 2 0 0 2 2 2 0 ABC transporter SLS PF14611.6 ORY14588.1 - 0.029 14.2 0.1 0.049 13.5 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial inner-membrane-bound regulator AAA_29 PF13555.6 ORY14588.1 - 0.039 13.7 0.3 0.07 12.9 0.3 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain SesA PF17107.5 ORY14588.1 - 0.041 14.1 3.2 0.11 12.7 3.2 1.7 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases ApoLp-III PF07464.11 ORY14588.1 - 0.041 14.0 5.1 0.086 12.9 5.1 1.6 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Filament PF00038.21 ORY14588.1 - 0.067 12.8 2.7 0.12 12.0 2.7 1.3 1 0 0 1 1 1 0 Intermediate filament protein Peptidase_C50 PF03568.17 ORY14588.1 - 0.068 12.3 1.9 0.11 11.6 1.9 1.3 1 0 0 1 1 1 0 Peptidase family C50 DUF4071 PF13281.6 ORY14588.1 - 0.1 11.6 1.1 0.18 10.8 1.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4071) RNA_helicase PF00910.22 ORY14588.1 - 0.12 12.8 0.0 0.28 11.6 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_22 PF13401.6 ORY14588.1 - 0.12 12.7 0.1 0.6 10.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain IDEAL PF08858.10 ORY14588.1 - 0.13 12.1 0.4 0.3 10.9 0.4 1.7 1 0 0 1 1 1 0 IDEAL domain MMR_HSR1 PF01926.23 ORY14588.1 - 0.15 12.1 0.0 1.5 8.9 0.0 2.6 3 0 0 3 3 3 0 50S ribosome-binding GTPase AAA_24 PF13479.6 ORY14588.1 - 0.16 11.7 0.3 0.83 9.3 0.0 2.4 2 1 0 2 2 2 0 AAA domain YPEB PF14620.6 ORY14588.1 - 0.19 11.1 2.7 0.32 10.3 2.7 1.3 1 0 0 1 1 1 0 YpeB sporulation Phasin PF05597.11 ORY14588.1 - 0.23 11.5 3.7 0.67 10.0 3.7 1.8 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF2617 PF10936.8 ORY14588.1 - 0.24 11.4 1.0 43 4.1 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function DUF2617 AAA_23 PF13476.6 ORY14588.1 - 1.1 9.8 5.0 3.2 8.2 0.0 2.8 3 0 0 3 3 3 0 AAA domain Cytochrom_B562 PF07361.11 ORY14588.1 - 1.1 9.9 6.5 0.88 10.3 2.5 2.6 2 1 1 3 3 3 0 Cytochrome b562 Pkinase PF00069.25 ORY14589.1 - 3.3e-46 157.8 0.0 5.8e-46 157.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY14589.1 - 9.8e-20 70.9 0.0 1.5e-19 70.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 ORY14589.1 - 0.00013 22.0 0.2 0.36 10.7 0.1 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 ORY14589.1 - 0.008 15.8 0.1 0.02 14.5 0.1 1.7 1 1 0 1 1 1 1 RIO1 family Kdo PF06293.14 ORY14589.1 - 0.11 11.8 0.1 0.19 11.1 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 ORY14589.1 - 0.15 11.3 0.0 0.38 10.0 0.0 1.5 1 1 0 1 1 1 0 Kinase-like SOG2 PF10428.9 ORY14589.1 - 6.2 5.9 11.4 8.7 5.4 11.4 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein SpoIIE PF07228.12 ORY14590.1 - 5.4e-08 33.0 0.2 1.5e-07 31.6 0.2 1.8 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 ORY14590.1 - 2e-07 30.9 0.1 0.0011 18.7 0.0 2.4 2 1 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 ORY14590.1 - 1.1e-05 25.2 0.4 2.5e-05 24.0 0.4 1.6 1 0 0 1 1 1 1 Protein phosphatase 2C WD40 PF00400.32 ORY14591.1 - 1.8e-36 123.5 11.3 1e-07 32.5 0.1 7.5 7 1 0 7 7 7 6 WD domain, G-beta repeat PRP4 PF08799.11 ORY14591.1 - 5.6e-13 48.2 1.2 5.6e-13 48.2 1.2 2.4 2 0 0 2 2 2 1 pre-mRNA processing factor 4 (PRP4) like ANAPC4_WD40 PF12894.7 ORY14591.1 - 1.1e-12 48.0 0.0 0.16 12.3 0.0 5.2 2 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ORY14591.1 - 0.00015 21.7 0.0 2.1 8.2 0.0 3.6 2 2 2 4 4 4 3 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 ORY14591.1 - 0.015 14.7 0.0 1.7 7.9 0.0 3.1 4 0 0 4 4 4 0 WD40-like domain Neocarzinostat PF00960.18 ORY14593.1 - 0.16 12.0 0.0 0.28 11.2 0.0 1.3 1 0 0 1 1 1 0 Neocarzinostatin family DUF3619 PF12279.8 ORY14593.1 - 7.1 7.0 7.4 0.22 11.9 0.9 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3619) bZIP_1 PF00170.21 ORY14594.1 - 9.5e-09 35.2 16.7 9.5e-09 35.2 16.7 2.0 2 0 0 2 2 2 1 bZIP transcription factor bZIP_Maf PF03131.17 ORY14594.1 - 5.7e-07 30.0 11.7 5.7e-07 30.0 11.7 2.3 1 1 1 2 2 2 1 bZIP Maf transcription factor bZIP_2 PF07716.15 ORY14594.1 - 0.0061 16.6 14.8 0.0061 16.6 14.8 2.7 2 2 0 2 2 2 1 Basic region leucine zipper Sel1 PF08238.12 ORY14596.1 - 3.4e-14 53.0 3.7 8.3e-06 26.3 0.2 4.2 5 0 0 5 5 5 3 Sel1 repeat zf-CCCH PF00642.24 ORY14597.1 - 1.5e-08 34.4 29.9 7e-05 22.6 0.2 5.6 4 1 1 5 5 5 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 ORY14597.1 - 4.5e-08 33.3 13.2 4.1e-06 27.0 2.6 3.4 1 1 2 3 3 3 3 Zinc-finger containing family zf_CCCH_4 PF18345.1 ORY14597.1 - 9.8e-06 25.5 36.5 0.00016 21.6 0.4 6.5 6 1 0 6 6 6 4 Zinc finger domain Torus PF16131.5 ORY14597.1 - 0.0011 19.6 21.2 0.0083 16.8 0.1 4.2 1 1 3 4 4 4 2 Torus domain zf-CCCH_4 PF18044.1 ORY14597.1 - 0.029 14.2 0.5 0.029 14.2 0.5 5.2 5 1 0 5 5 5 0 CCCH-type zinc finger CBF PF03914.17 ORY14599.1 - 6.4e-37 127.2 1.8 8.4e-37 126.8 0.0 2.1 3 0 0 3 3 3 1 CBF/Mak21 family Mt_ATP-synt_B PF05405.14 ORY14600.1 - 4.9e-49 166.1 6.2 6.2e-49 165.8 6.2 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Ehrlichia_rpt PF09528.10 ORY14600.1 - 0.045 13.2 0.3 0.11 12.0 0.3 1.6 1 0 0 1 1 1 0 Ehrlichia tandem repeat (Ehrlichia_rpt) Promethin PF16015.5 ORY14601.1 - 0.12 12.3 8.9 0.28 11.1 8.9 1.5 1 0 0 1 1 1 0 Promethin Phage_holin_3_6 PF07332.11 ORY14601.1 - 0.21 11.7 2.6 0.35 10.9 2.6 1.3 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III GPI-anchored PF10342.9 ORY14602.1 - 4.2e-09 37.0 0.2 4.2e-09 37.0 0.2 2.5 1 1 2 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family AlcCBM31 PF11606.8 ORY14602.1 - 0.058 13.6 0.0 0.62 10.3 0.0 2.2 2 0 0 2 2 2 0 Family 31 carbohydrate binding protein Choline_sulf_C PF12411.8 ORY14612.1 - 0.078 12.8 0.0 0.21 11.4 0.0 1.7 1 0 0 1 1 1 0 Choline sulfatase enzyme C terminal AgrB PF04647.15 ORY14612.1 - 0.13 11.5 3.5 0.19 11.0 3.5 1.1 1 0 0 1 1 1 0 Accessory gene regulator B DUF2070 PF09843.9 ORY14612.1 - 3.2 5.9 5.1 4.4 5.5 5.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) GRAM PF02893.20 ORY14615.1 - 0.056 13.3 0.0 0.081 12.8 0.0 1.3 1 0 0 1 1 1 0 GRAM domain Vps36_ESCRT-II PF11605.8 ORY14615.1 - 0.18 12.0 0.0 0.29 11.4 0.0 1.3 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 Thiolase_N PF00108.23 ORY14616.1 - 2.6e-73 246.6 4.5 2.6e-73 246.6 4.5 1.4 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 ORY14616.1 - 4e-46 155.6 0.1 1e-45 154.3 0.1 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III PF08545.10 ORY14616.1 - 0.073 12.9 0.3 12 5.8 0.1 2.7 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III adh_short PF00106.25 ORY14617.1 - 1.4e-06 27.9 0.0 0.08 12.4 0.0 3.2 2 1 1 3 3 3 3 short chain dehydrogenase zf-C3H2C3 PF17122.5 ORY14619.1 - 0.9 9.6 6.3 0.36 10.9 3.6 1.9 2 1 0 2 2 2 0 Zinc-finger FGGY_C PF02782.16 ORY14621.1 - 4.6e-74 248.4 1.6 1.2e-73 247.1 0.8 1.9 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 ORY14621.1 - 4.8e-66 222.8 0.0 6.6e-66 222.4 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.20 ORY14621.1 - 0.12 11.9 0.8 0.45 10.0 0.0 2.1 3 0 0 3 3 3 0 BadF/BadG/BcrA/BcrD ATPase family DUF3429 PF11911.8 ORY14622.1 - 6.1e-43 146.6 14.6 8.1e-43 146.2 14.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) RP-C_C PF11800.8 ORY14622.1 - 0.15 12.1 4.7 0.33 11.0 4.7 1.5 1 0 0 1 1 1 0 Replication protein C C-terminal region Neur_chan_memb PF02932.16 ORY14622.1 - 0.2 11.7 0.3 0.38 10.8 0.0 1.5 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region HSP70 PF00012.20 ORY14623.1 - 2.3e-259 861.7 6.8 2.6e-259 861.5 6.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 ORY14623.1 - 5.3e-17 61.6 0.0 6.6e-16 58.0 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 ORY14623.1 - 0.0028 17.4 0.0 0.0096 15.7 0.0 1.9 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 ORY14623.1 - 0.015 15.7 3.9 6 7.3 0.0 3.5 3 2 0 3 3 3 0 Cell division protein FtsA Hydantoinase_A PF01968.18 ORY14623.1 - 0.025 13.8 0.1 0.055 12.7 0.1 1.5 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase DUF3128 PF11326.8 ORY14624.1 - 1.2e-24 86.5 2.4 1.3e-24 86.3 2.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) VPS13_mid_rpt PF16910.5 ORY14625.1 - 2.3e-101 338.1 16.7 1.9e-98 328.6 1.4 5.3 3 1 0 3 3 3 2 Repeating coiled region of VPS13 SHR-BD PF06650.12 ORY14625.1 - 1.6e-98 329.4 0.0 7e-98 327.3 0.0 2.2 3 0 0 3 3 3 1 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13 PF16908.5 ORY14625.1 - 1.2e-86 290.4 1.5 2.5e-82 276.2 0.0 5.0 6 0 0 6 6 6 1 Vacuolar sorting-associated protein 13, N-terminal VPS13_C PF16909.5 ORY14625.1 - 4.4e-72 241.6 7.1 4e-69 232.0 0.3 2.9 3 0 0 3 3 3 2 Vacuolar-sorting-associated 13 protein C-terminal Chorein_N PF12624.7 ORY14625.1 - 8.9e-41 138.7 0.0 3.2e-40 136.9 0.0 2.1 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 ORY14625.1 - 0.0001 22.6 0.0 0.00032 21.0 0.0 1.9 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain PUD PF03714.14 ORY14625.1 - 0.27 12.1 1.5 3.5 8.6 0.1 3.2 3 0 0 3 3 3 0 Bacterial pullanase-associated domain Tho1_MOS11_C PF18592.1 ORY14625.1 - 1.8 8.4 4.8 8 6.4 2.2 2.7 2 0 0 2 2 2 0 Tho1/MOS11 C-terminal domain Chitin_bind_1 PF00187.19 ORY14626.1 - 3e-17 62.8 73.1 2.1e-06 28.1 19.1 3.6 3 0 0 3 3 3 3 Chitin recognition protein adh_short PF00106.25 ORY14627.1 - 8.8e-23 80.8 0.0 1e-18 67.5 0.0 2.0 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 ORY14627.1 - 4.7e-14 52.5 0.0 3.8e-13 49.5 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY14627.1 - 6.9e-06 26.1 0.0 1.1e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 KR domain bZIP_2 PF07716.15 ORY14628.1 - 1.7e-05 24.8 6.3 2.8e-05 24.1 6.3 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 ORY14628.1 - 0.0022 18.1 6.8 0.0022 18.1 6.8 1.7 2 0 0 2 2 2 1 bZIP transcription factor F-box-like PF12937.7 ORY14629.1 - 4.5e-05 23.3 0.2 0.00012 21.9 0.0 1.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 ORY14629.1 - 0.00083 19.2 0.1 0.0016 18.2 0.1 1.5 1 0 0 1 1 1 1 F-box domain G-alpha PF00503.20 ORY14630.1 - 3.5e-51 174.4 1.2 6.1e-51 173.7 0.1 1.8 2 0 0 2 2 2 1 G-protein alpha subunit Arf PF00025.21 ORY14630.1 - 0.0016 17.9 2.2 0.32 10.4 0.1 2.9 3 0 0 3 3 3 2 ADP-ribosylation factor family LRR_4 PF12799.7 ORY14634.1 - 0.54 10.8 1.9 13 6.4 0.0 4.0 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) ABC2_membrane PF01061.24 ORY14635.1 - 3.9e-91 304.1 52.6 1e-47 162.3 24.9 2.5 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 ORY14635.1 - 6.6e-39 133.6 0.2 5.4e-18 65.8 0.0 3.5 4 0 0 4 4 3 2 ABC transporter PDR_CDR PF06422.12 ORY14635.1 - 5e-32 109.7 1.6 3e-30 103.9 0.1 3.7 5 0 0 5 5 3 2 CDR ABC transporter ABC_trans_N PF14510.6 ORY14635.1 - 1.7e-19 70.2 0.0 1.7e-19 70.2 0.0 2.9 3 0 0 3 3 2 1 ABC-transporter N-terminal AAA_25 PF13481.6 ORY14635.1 - 4e-06 26.6 0.1 8.8e-05 22.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 ORY14635.1 - 4.9e-06 27.0 1.5 0.0021 18.5 0.1 2.8 3 0 0 3 3 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 ORY14635.1 - 1.8e-05 24.7 0.2 0.0072 16.2 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase SMC_N PF02463.19 ORY14635.1 - 2.9e-05 23.6 0.0 0.12 11.8 0.0 3.4 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 ORY14635.1 - 0.00023 21.1 0.1 0.65 9.7 0.0 2.8 2 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_33 PF13671.6 ORY14635.1 - 0.00028 21.0 0.5 0.21 11.7 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.6 ORY14635.1 - 0.00031 20.4 1.4 0.02 14.7 0.2 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.6 ORY14635.1 - 0.0028 18.2 8.8 0.059 13.9 0.0 3.5 3 0 0 3 3 3 1 AAA domain Mem_trans PF03547.18 ORY14635.1 - 0.0044 15.5 0.0 0.0085 14.5 0.0 1.4 1 0 0 1 1 1 1 Membrane transport protein AAA_22 PF13401.6 ORY14635.1 - 0.0045 17.3 0.2 0.7 10.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 ORY14635.1 - 0.049 13.6 0.0 0.59 10.0 0.0 2.2 2 0 0 2 2 2 0 Rad17 P-loop domain cobW PF02492.19 ORY14635.1 - 0.049 13.2 1.0 0.48 10.0 0.1 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.6 ORY14635.1 - 0.075 12.7 0.3 13 5.4 0.2 2.4 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 ORY14635.1 - 0.076 12.7 1.1 9.5 5.9 0.6 2.4 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 ORY14635.1 - 0.1 13.1 0.0 0.1 13.1 0.0 2.1 3 0 0 3 3 1 0 AAA domain NACHT PF05729.12 ORY14635.1 - 0.13 12.2 1.0 5.1 7.0 0.3 2.6 2 0 0 2 2 2 0 NACHT domain AAA PF00004.29 ORY14635.1 - 0.18 12.2 1.2 17 5.9 0.0 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ABC2_membrane_3 PF12698.7 ORY14635.1 - 2.8 6.9 42.3 0.21 10.6 17.2 2.8 2 1 0 2 2 2 0 ABC-2 family transporter protein WD40 PF00400.32 ORY14636.1 - 3.1e-27 94.3 17.3 6e-06 26.9 0.1 7.9 8 0 0 8 8 8 5 WD domain, G-beta repeat F-box-like PF12937.7 ORY14636.1 - 7.5e-11 41.8 0.9 1.6e-10 40.7 0.9 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY14636.1 - 7.9e-07 28.8 0.3 1.6e-06 27.9 0.3 1.5 1 0 0 1 1 1 1 F-box domain ANAPC4_WD40 PF12894.7 ORY14636.1 - 4e-05 23.8 0.1 0.71 10.2 0.0 4.0 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ORY14636.1 - 0.00027 19.7 0.1 1.3 7.5 0.0 3.1 3 0 0 3 3 3 2 Nucleoporin Nup120/160 PH_10 PF15411.6 ORY14637.1 - 2.6e-39 134.3 0.4 5.2e-39 133.3 0.4 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain CDC24 PF06395.11 ORY14637.1 - 7.8e-35 119.0 0.1 6.7e-34 116.0 0.0 2.2 2 0 0 2 2 2 1 CDC24 Calponin RhoGEF PF00621.20 ORY14637.1 - 1.9e-30 106.4 0.4 3.8e-30 105.5 0.4 1.5 1 0 0 1 1 1 1 RhoGEF domain PB1 PF00564.24 ORY14637.1 - 6.2e-10 38.9 0.1 1.7e-09 37.5 0.1 1.7 1 0 0 1 1 1 1 PB1 domain DCB PF16213.5 ORY14637.1 - 0.082 12.6 0.2 0.19 11.4 0.2 1.5 1 0 0 1 1 1 0 Dimerisation and cyclophilin-binding domain of Mon2 PH PF00169.29 ORY14637.1 - 0.11 13.0 0.1 0.28 11.7 0.1 1.7 1 0 0 1 1 1 0 PH domain Nramp PF01566.18 ORY14639.1 - 1.4e-84 284.1 18.4 1.4e-84 284.1 18.4 2.4 2 1 0 2 2 2 1 Natural resistance-associated macrophage protein Acetyltransf_10 PF13673.7 ORY14640.1 - 2.4e-10 40.4 0.0 4.6e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORY14640.1 - 2.4e-08 34.2 0.0 4.9e-08 33.2 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ORY14640.1 - 3.3e-06 27.4 0.0 5.8e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 ORY14640.1 - 0.00058 19.9 0.0 0.0011 19.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 ORY14640.1 - 0.023 14.8 0.0 0.045 13.9 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase DUF829 PF05705.14 ORY14641.1 - 2.7e-13 50.4 0.3 2.8e-13 50.3 0.3 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) DUF3630 PF12305.8 ORY14641.1 - 0.032 14.3 0.1 0.032 14.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3630) Methyltransf_25 PF13649.6 ORY14647.1 - 7.5e-10 39.4 0.0 1.2e-09 38.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY14647.1 - 2.2e-07 31.4 0.0 3.5e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY14647.1 - 3.3e-06 27.8 0.0 5.3e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY14647.1 - 7e-06 25.9 0.0 3.2e-05 23.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORY14647.1 - 0.0016 17.9 0.0 0.0023 17.3 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 ORY14647.1 - 0.0023 17.8 0.0 0.0039 17.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_33 PF10017.9 ORY14647.1 - 0.0091 15.2 0.0 0.012 14.8 0.0 1.1 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent Methyltransf_28 PF02636.17 ORY14647.1 - 0.15 11.7 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase F-box-like PF12937.7 ORY14651.1 - 0.079 12.9 0.0 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 F-box-like His_Phos_1 PF00300.22 ORY14653.1 - 9.5e-18 64.6 0.1 2e-09 37.4 0.1 2.1 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) MFS_1 PF07690.16 ORY14654.1 - 1.9e-14 53.4 29.6 1.9e-14 53.4 29.6 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily MVL PF12151.8 ORY14654.1 - 0.1 12.5 0.5 4 7.4 0.2 2.3 2 0 0 2 2 2 0 Mannan-binding protein MACPF PF01823.19 ORY14656.1 - 1.1e-06 28.9 0.9 1.4e-06 28.5 0.0 1.5 2 0 0 2 2 2 1 MAC/Perforin domain Aegerolysin PF06355.13 ORY14657.1 - 5.9e-19 68.4 0.2 6.6e-19 68.3 0.2 1.0 1 0 0 1 1 1 1 Aegerolysin Glyco_hydro_61 PF03443.14 ORY14658.1 - 1.7e-55 188.2 0.2 2.1e-55 187.9 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 MG2 PF01835.19 ORY14658.1 - 0.11 12.9 0.0 0.2 12.1 0.0 1.5 1 0 0 1 1 1 0 MG2 domain NAR2 PF16974.5 ORY14658.1 - 0.12 11.8 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 High-affinity nitrate transporter accessory ABC_tran PF00005.27 ORY14659.1 - 1.3e-33 116.5 0.0 3.1e-33 115.2 0.0 1.7 2 0 0 2 2 1 1 ABC transporter ABC_membrane PF00664.23 ORY14659.1 - 5.1e-21 75.5 16.4 7.6e-21 75.0 16.4 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 ORY14659.1 - 5.8e-06 25.9 0.0 0.0038 16.7 0.0 2.4 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 ORY14659.1 - 0.00067 19.9 0.2 0.002 18.4 0.1 1.8 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 ORY14659.1 - 0.0015 18.2 0.2 0.004 16.9 0.2 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 ORY14659.1 - 0.018 14.9 0.0 0.047 13.6 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 ORY14659.1 - 0.027 14.9 0.2 0.083 13.3 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain Secretin PF00263.21 ORY14659.1 - 0.041 13.5 0.2 0.072 12.7 0.2 1.3 1 0 0 1 1 1 0 Bacterial type II and III secretion system protein AAA_24 PF13479.6 ORY14659.1 - 0.054 13.2 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.7 ORY14659.1 - 0.073 12.0 0.0 0.17 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain DUF87 PF01935.17 ORY14659.1 - 0.13 12.3 0.0 0.24 11.5 0.0 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain SbcCD_C PF13558.6 ORY14659.1 - 0.15 12.4 0.1 1.8 8.8 0.1 2.5 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.6 ORY14659.1 - 0.16 11.7 0.0 0.55 10.0 0.0 1.9 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 ORY14659.1 - 0.24 11.1 0.0 0.35 10.5 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain Aminotran_1_2 PF00155.21 ORY14660.1 - 7.2e-42 143.8 0.0 8.8e-42 143.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Pyr_redox_2 PF07992.14 ORY14661.1 - 1.5e-19 70.3 0.0 7.4e-19 68.1 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ORY14661.1 - 9.3e-05 21.7 0.0 0.11 11.6 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.6 ORY14661.1 - 0.00026 20.4 0.0 0.15 11.3 0.0 2.6 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ORY14661.1 - 0.00062 18.6 0.0 0.33 9.6 0.0 2.6 3 0 0 3 3 3 2 HI0933-like protein GIDA PF01134.22 ORY14661.1 - 0.024 13.7 0.3 0.49 9.4 0.1 2.4 1 1 1 2 2 2 0 Glucose inhibited division protein A FAD_binding_3 PF01494.19 ORY14661.1 - 0.026 13.8 0.1 0.06 12.6 0.1 1.6 1 1 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.7 ORY14661.1 - 0.048 13.0 0.7 1.5 8.1 0.1 2.2 1 1 1 2 2 2 0 FAD dependent oxidoreductase DAO PF01266.24 ORY14661.1 - 0.091 12.3 1.4 4 6.9 0.1 2.5 2 1 0 3 3 3 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 ORY14661.1 - 0.2 12.3 0.3 19 5.9 0.3 3.3 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ORY14662.1 - 5.3e-18 65.3 0.0 1.3e-09 37.7 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ORY14662.1 - 3e-05 22.9 0.0 0.0091 14.7 0.0 2.3 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_3 PF13738.6 ORY14662.1 - 4.2e-05 23.0 1.2 0.023 14.0 0.2 2.7 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ORY14662.1 - 7.3e-05 22.8 0.2 0.29 11.1 0.0 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 ORY14662.1 - 0.0002 20.6 0.8 0.0015 17.7 0.1 2.4 2 1 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.19 ORY14662.1 - 0.00028 20.2 0.0 0.00056 19.3 0.0 1.5 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 ORY14662.1 - 0.0007 19.3 0.4 0.003 17.2 0.1 1.9 1 1 1 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ORY14662.1 - 0.0015 18.7 0.4 0.013 15.7 0.1 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 ORY14662.1 - 0.03 13.4 0.4 1.2 8.1 0.1 2.4 1 1 1 2 2 2 0 Glucose inhibited division protein A Thi4 PF01946.17 ORY14662.1 - 0.07 12.4 0.7 0.15 11.2 0.1 1.8 2 0 0 2 2 2 0 Thi4 family Trp_halogenase PF04820.14 ORY14662.1 - 0.1 11.5 0.1 0.15 10.9 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Methyltransf_2 PF00891.18 ORY14663.1 - 3.5e-35 121.2 0.0 7.1e-35 120.2 0.0 1.5 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 ORY14663.1 - 1.3e-05 25.0 0.0 3.4e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 Dimerisation domain SesA PF17107.5 ORY14663.1 - 0.067 13.4 1.0 6.6 6.9 0.0 3.3 3 0 0 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases PDZ_3 PF17815.1 ORY14663.1 - 0.096 12.5 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 PDZ domain MBOAT_2 PF13813.6 ORY14665.1 - 1.6e-19 70.0 5.3 3.7e-19 68.8 5.3 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family GST_C PF00043.25 ORY14666.1 - 7.4e-07 29.3 0.0 1.5e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 ORY14666.1 - 1.2e-06 28.7 0.0 2.2e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 ORY14666.1 - 5.2e-06 26.6 0.0 1.2e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 ORY14666.1 - 5.5e-05 23.1 1.3 6.3e-05 22.9 0.1 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 ORY14666.1 - 0.00028 21.2 0.1 0.00047 20.5 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 ORY14666.1 - 0.00034 20.9 0.1 0.0007 19.9 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Tom37 PF10568.9 ORY14666.1 - 0.018 15.3 0.0 0.04 14.2 0.0 1.5 1 1 0 1 1 1 0 Outer mitochondrial membrane transport complex protein GST_C_6 PF17171.4 ORY14666.1 - 0.17 11.7 0.0 0.36 10.7 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain p450 PF00067.22 ORY14667.1 - 8.1e-46 156.7 0.0 1.3e-45 156.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 NADPH_Ox PF08414.10 ORY14667.1 - 0.21 12.0 2.7 0.75 10.2 0.1 2.8 3 1 1 4 4 4 0 Respiratory burst NADPH oxidase Zn_clus PF00172.18 ORY14668.1 - 5.1e-06 26.5 6.1 9.3e-06 25.7 6.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_25 PF13649.6 ORY14669.1 - 0.00081 20.0 0.0 0.002 18.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY14669.1 - 0.0011 18.9 0.0 0.0037 17.1 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY14669.1 - 0.019 15.6 0.0 0.12 13.0 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Ubie_methyltran PF01209.18 ORY14669.1 - 0.033 13.5 0.0 0.057 12.8 0.0 1.5 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 ORY14669.1 - 0.061 14.1 0.0 0.22 12.3 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain p450 PF00067.22 ORY14671.1 - 1.1e-60 205.7 0.0 1.4e-60 205.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Patatin PF01734.22 ORY14672.1 - 4.1e-09 36.9 0.0 0.00086 19.5 0.0 2.4 2 0 0 2 2 2 2 Patatin-like phospholipase Sensor PF13796.6 ORY14674.1 - 0.021 14.9 1.3 0.021 14.9 1.3 2.1 2 0 0 2 2 2 0 Putative sensor DUF3522 PF12036.8 ORY14674.1 - 0.025 14.9 0.5 0.025 14.9 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3522) FAM70 PF14967.6 ORY14674.1 - 0.89 9.0 3.1 2.2 7.7 0.1 2.0 1 1 1 2 2 2 0 FAM70 protein DUF4491 PF14898.6 ORY14674.1 - 2.8 8.4 9.3 0.66 10.5 2.6 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4491) SET PF00856.28 ORY14676.1 - 2.1e-06 28.2 0.0 5.4e-06 26.9 0.0 1.8 1 1 0 1 1 1 1 SET domain Aha1_N PF09229.11 ORY14677.1 - 7.6e-41 139.5 0.9 1.1e-40 139.0 0.9 1.3 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 ORY14677.1 - 1e-19 71.0 1.5 1.2e-19 70.8 0.7 1.5 2 0 0 2 2 2 1 Activator of Hsp90 ATPase homolog 1-like protein Polyketide_cyc2 PF10604.9 ORY14677.1 - 7.6e-05 23.0 2.3 0.34 11.2 1.5 2.2 2 0 0 2 2 2 2 Polyketide cyclase / dehydrase and lipid transport Peptidase_S10 PF00450.22 ORY14679.1 - 1.2e-92 311.5 6.1 1.6e-92 311.1 6.1 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase HECT PF00632.25 ORY14682.1 - 2.4e-82 276.8 0.0 4.7e-82 275.9 0.0 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IQ PF00612.27 ORY14682.1 - 0.013 15.2 0.9 0.063 13.1 0.9 2.2 1 0 0 1 1 1 0 IQ calmodulin-binding motif DUF3074 PF11274.8 ORY14682.1 - 0.13 12.2 0.0 16 5.4 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3074) Sugar_tr PF00083.24 ORY14683.1 - 9.5e-43 146.7 10.6 1.2e-42 146.4 10.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY14683.1 - 3.1e-35 121.7 24.5 3.1e-35 121.7 24.5 2.1 2 1 1 3 3 3 1 Major Facilitator Superfamily OATP PF03137.20 ORY14683.1 - 1.3e-05 23.7 2.0 5.7e-05 21.6 0.4 2.1 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family ATG22 PF11700.8 ORY14683.1 - 0.012 14.3 0.8 0.012 14.3 0.8 2.3 2 0 0 2 2 2 0 Vacuole effluxer Atg22 like TRI12 PF06609.13 ORY14683.1 - 0.023 13.2 2.9 0.027 12.9 0.3 2.1 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) DUF3176 PF11374.8 ORY14684.1 - 8.6e-16 58.1 3.4 8.6e-16 58.1 3.4 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) DUF2070 PF09843.9 ORY14684.1 - 2.1 6.5 3.8 3.7 5.7 1.4 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) DUF3123 PF11321.8 ORY14685.1 - 0.13 13.0 2.1 9 7.0 0.6 3.8 1 1 2 3 3 3 0 Protein of unknown function (DUF3123) SCVP PF17619.2 ORY14685.1 - 0.23 12.4 0.0 56 4.7 0.0 3.6 3 1 2 5 5 5 0 Secreted clade V proteins AAA_12 PF13087.6 ORY14688.1 - 4.1e-28 98.4 0.0 6.8e-28 97.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 ORY14688.1 - 1.1e-20 74.5 0.0 9.7e-13 48.5 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 ORY14688.1 - 1e-07 32.4 0.0 9.9e-07 29.2 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 ORY14688.1 - 7.3e-07 29.1 0.0 2.2e-06 27.5 0.0 1.8 2 0 0 2 2 2 1 AAA domain UvrD-helicase PF00580.21 ORY14688.1 - 3.8e-06 26.7 0.1 1.2e-05 25.0 0.0 1.8 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain Helicase_RecD PF05127.14 ORY14688.1 - 2.6e-05 24.2 0.0 8.5e-05 22.5 0.0 1.9 1 1 0 1 1 1 1 Helicase ResIII PF04851.15 ORY14688.1 - 0.00039 20.5 0.0 0.00065 19.8 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 ORY14688.1 - 0.004 17.4 0.0 0.011 16.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ORY14688.1 - 0.04 14.3 0.0 0.17 12.3 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA PF00004.29 ORY14688.1 - 0.053 14.0 0.0 0.18 12.2 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 ORY14688.1 - 0.13 12.8 0.0 0.32 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF4360 PF14273.6 ORY14689.1 - 8.9e-35 120.2 0.1 1.1e-34 119.8 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DEC-1_N PF04625.13 ORY14689.1 - 0.19 10.7 0.6 0.25 10.3 0.6 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region L_HMGIC_fpl PF10242.9 ORY14690.1 - 1.7e-06 28.4 6.1 3.3e-06 27.4 6.1 1.6 1 1 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein Claudin_3 PF06653.11 ORY14690.1 - 0.038 13.9 11.0 1.1 9.2 0.0 3.0 2 1 1 3 3 3 0 Tight junction protein, Claudin-like SpoU_methylase PF00588.19 ORY14691.1 - 6.2e-22 78.3 0.0 6.7e-21 74.9 0.0 2.0 1 1 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 ORY14691.1 - 0.019 15.2 0.0 0.05 13.9 0.0 1.7 2 0 0 2 2 2 0 RNA 2'-O ribose methyltransferase substrate binding zf-PHD-like PF15446.6 ORY14692.1 - 1.9e-67 226.1 12.9 4.9e-67 224.8 12.9 1.7 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain SNF2_N PF00176.23 ORY14692.1 - 2.7e-52 177.7 0.0 4.3e-52 177.0 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-CCCH_6 PF18585.1 ORY14692.1 - 1e-27 95.8 0.5 1e-27 95.8 0.5 2.1 2 0 0 2 2 2 1 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 Helicase_C PF00271.31 ORY14692.1 - 7.2e-20 71.4 0.0 1.4e-19 70.4 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 ORY14692.1 - 1.6e-08 34.1 0.3 6.1e-08 32.2 0.3 1.9 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.15 ORY14692.1 - 2.9e-08 33.9 0.0 8.6e-08 32.4 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Chromo PF00385.24 ORY14692.1 - 7e-06 25.8 5.1 0.26 11.2 0.5 3.9 4 0 0 4 4 4 3 Chromo (CHRromatin Organisation MOdifier) domain PHD PF00628.29 ORY14692.1 - 0.00012 21.9 5.4 0.00012 21.9 5.4 4.1 3 2 1 4 4 4 2 PHD-finger DUF1087 PF06465.13 ORY14692.1 - 0.0011 18.9 0.0 0.0035 17.3 0.0 1.9 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1087) GMC_oxred_N PF00732.19 ORY14693.1 - 1.2e-27 97.1 0.0 2.6e-27 96.0 0.0 1.5 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 ORY14693.1 - 3.9e-16 59.9 0.0 8.3e-16 58.8 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 ORY14693.1 - 6.6e-07 28.7 0.0 4.7e-05 22.7 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.19 ORY14693.1 - 2e-05 24.0 0.0 3.1e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 ORY14693.1 - 9.9e-05 21.2 0.0 0.00021 20.2 0.1 1.4 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.6 ORY14693.1 - 0.00055 20.1 0.0 0.0018 18.5 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 ORY14693.1 - 0.00059 19.3 0.5 0.0048 16.3 0.6 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ORY14693.1 - 0.00072 18.9 0.0 0.0012 18.2 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 ORY14693.1 - 0.0013 17.9 0.0 0.0019 17.3 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 ORY14693.1 - 0.0028 16.9 0.0 0.031 13.5 0.0 2.1 2 0 0 2 2 2 1 Thi4 family Pyr_redox_3 PF13738.6 ORY14693.1 - 0.0054 16.0 0.1 0.01 15.1 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 ORY14693.1 - 0.025 13.7 1.0 0.049 12.7 0.1 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A DAO PF01266.24 ORY14693.1 - 0.04 13.5 0.1 0.26 10.8 0.1 2.2 3 0 0 3 3 3 0 FAD dependent oxidoreductase Rhodanese PF00581.20 ORY14695.1 - 5.7e-05 23.6 0.0 7.7e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain FMN_red PF03358.15 ORY14696.1 - 1.1e-22 80.5 0.0 1.6e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Cellulase PF00150.18 ORY14697.1 - 4.9e-08 32.8 3.7 4.9e-07 29.5 3.8 2.4 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_47 PF01532.20 ORY14698.1 - 9.9e-07 28.0 0.0 1.3e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Xan_ur_permease PF00860.20 ORY14700.1 - 1.6e-22 79.7 31.3 3.4e-21 75.4 31.3 2.6 1 1 0 1 1 1 1 Permease family Flp_Fap PF04964.14 ORY14700.1 - 0.037 13.9 2.9 0.18 11.7 1.1 2.7 2 0 0 2 2 2 0 Flp/Fap pilin component DUF3018 PF11455.8 ORY14701.1 - 0.087 12.8 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3018) Complex1_51K PF01512.17 ORY14702.1 - 2.1e-47 160.8 0.0 3.6e-47 160.1 0.0 1.4 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 ORY14702.1 - 9.4e-30 102.5 1.2 2.3e-29 101.3 0.2 2.1 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 ORY14702.1 - 3.1e-09 36.6 0.0 9.4e-09 35.0 0.0 1.9 2 0 0 2 2 2 1 SLBB domain GHMP_kinases_C PF08544.13 ORY14702.1 - 0.11 12.9 0.0 23 5.4 0.0 2.5 2 0 0 2 2 2 0 GHMP kinases C terminal DUF3568 PF12092.8 ORY14702.1 - 0.15 12.2 0.4 0.27 11.3 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3568) EF-hand_1 PF00036.32 ORY14703.1 - 2.8e-19 67.1 6.3 3.5e-07 29.3 0.2 3.3 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 ORY14703.1 - 2.7e-18 66.2 4.9 3.6e-12 46.6 0.4 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 ORY14703.1 - 1.6e-17 61.8 4.2 4e-06 26.3 0.2 3.6 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.6 ORY14703.1 - 2.3e-16 59.3 4.0 4.6e-11 42.4 0.3 3.2 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 ORY14703.1 - 4.7e-11 41.7 3.2 8.4e-05 21.9 0.1 3.4 3 0 0 3 3 3 3 EF hand EF-hand_4 PF12763.7 ORY14703.1 - 2.1e-06 27.6 0.1 0.0015 18.4 0.0 2.3 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 ORY14703.1 - 0.012 15.9 2.1 0.67 10.3 1.1 2.2 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region DUF1296 PF06972.11 ORY14703.1 - 0.016 15.3 0.0 0.094 12.9 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1296) CNTF PF01110.17 ORY14703.1 - 0.052 12.9 0.2 0.092 12.1 0.2 1.4 1 0 0 1 1 1 0 Ciliary neurotrophic factor Caleosin PF05042.13 ORY14703.1 - 0.075 13.0 0.0 4.8 7.1 0.0 2.8 2 1 1 3 3 3 0 Caleosin related protein Nup96 PF12110.8 ORY14704.1 - 1.1e-80 270.8 0.0 1.6e-80 270.3 0.0 1.2 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.14 ORY14704.1 - 3.8e-44 150.4 0.0 7e-44 149.5 0.0 1.5 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.6 ORY14704.1 - 2.8e-21 76.1 170.8 5.3e-10 40.0 36.3 12.5 5 2 6 11 11 11 5 Nucleoporin FG repeat region SesA PF17107.5 ORY14705.1 - 1.5e-09 38.0 0.0 8.4e-08 32.4 0.0 2.5 2 0 0 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases NACHT PF05729.12 ORY14705.1 - 4.7e-07 29.9 0.0 1.5e-06 28.2 0.0 1.9 1 0 0 1 1 1 1 NACHT domain Ank PF00023.30 ORY14705.1 - 4.3e-06 26.9 0.1 2.1 8.9 0.0 4.7 4 0 0 4 4 4 1 Ankyrin repeat AAA_16 PF13191.6 ORY14705.1 - 1.6e-05 25.3 0.8 6.5e-05 23.4 0.0 2.4 3 0 0 3 3 2 1 AAA ATPase domain Ank_4 PF13637.6 ORY14705.1 - 3.2e-05 24.4 0.0 2.2 8.9 0.0 4.5 4 0 0 4 4 4 1 Ankyrin repeats (many copies) AAA_22 PF13401.6 ORY14705.1 - 0.0035 17.6 0.0 0.011 16.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 ORY14705.1 - 0.0046 17.5 0.0 0.016 15.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 ORY14705.1 - 0.0057 17.2 0.0 0.017 15.7 0.0 1.8 1 0 0 1 1 1 1 ABC transporter Transposase_mut PF00872.18 ORY14705.1 - 0.0064 15.4 0.1 0.011 14.7 0.1 1.2 1 0 0 1 1 1 1 Transposase, Mutator family DUF2075 PF09848.9 ORY14705.1 - 0.015 14.5 0.5 2.9 7.1 0.2 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.22 ORY14705.1 - 0.027 14.8 0.1 0.062 13.7 0.1 1.6 1 0 0 1 1 1 0 RNA helicase Ank_2 PF12796.7 ORY14705.1 - 0.05 14.2 0.0 1.1e+02 3.5 0.0 4.1 2 1 2 4 4 4 0 Ankyrin repeats (3 copies) DALR_1 PF05746.15 ORY14705.1 - 0.088 13.0 0.2 0.29 11.3 0.0 2.0 2 0 0 2 2 1 0 DALR anticodon binding domain Ank_5 PF13857.6 ORY14705.1 - 0.092 13.1 0.0 52 4.3 0.0 4.0 3 0 0 3 3 3 0 Ankyrin repeats (many copies) NB-ARC PF00931.22 ORY14705.1 - 0.13 11.4 0.0 0.37 9.9 0.0 1.7 1 0 0 1 1 1 0 NB-ARC domain AAA_33 PF13671.6 ORY14705.1 - 0.15 12.2 3.3 0.52 10.5 0.1 3.1 4 0 0 4 4 3 0 AAA domain Viral_helicase1 PF01443.18 ORY14705.1 - 0.15 11.7 0.0 0.33 10.7 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_29 PF13555.6 ORY14705.1 - 0.16 11.7 0.5 0.39 10.5 0.1 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain ATP_bind_1 PF03029.17 ORY14705.1 - 0.25 11.1 0.5 0.69 9.6 0.1 1.9 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Glyco_hydro_61 PF03443.14 ORY14706.1 - 3.8e-30 105.4 0.0 5.9e-30 104.8 0.0 1.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 61 Ndc1_Nup PF09531.10 ORY14707.1 - 0.0033 16.2 3.4 0.0033 16.2 3.4 1.6 2 0 0 2 2 2 1 Nucleoporin protein Ndc1-Nup UL41A PF17591.2 ORY14707.1 - 0.14 12.3 3.5 0.31 11.1 1.3 2.5 2 0 0 2 2 2 0 Herpesvirus UL41A DUF4191 PF13829.6 ORY14707.1 - 7.8 5.8 5.5 30 3.9 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) NAD_binding_1 PF00175.21 ORY14708.1 - 1.2e-08 35.5 0.0 2.5e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Globin PF00042.22 ORY14708.1 - 1.4e-06 28.8 0.0 2.8e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Globin Protoglobin PF11563.8 ORY14708.1 - 0.00017 21.5 0.0 0.00027 20.8 0.0 1.3 1 0 0 1 1 1 1 Protoglobin NAD_binding_6 PF08030.12 ORY14708.1 - 0.075 13.1 0.0 0.72 10.0 0.0 2.2 2 0 0 2 2 2 0 Ferric reductase NAD binding domain NOA36 PF06524.12 ORY14709.1 - 1.3 8.3 11.9 1.6 8.0 11.9 1.1 1 0 0 1 1 1 0 NOA36 protein tRNA-synt_1d PF00750.19 ORY14741.1 - 0.031 13.2 0.0 0.045 12.7 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (R) p450 PF00067.22 ORY14742.1 - 2.2e-35 122.3 0.0 9e-34 117.0 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 PQQ_2 PF13360.6 ORY14743.1 - 1.3e-08 34.7 1.4 0.0018 17.9 0.3 3.6 1 1 1 3 3 3 3 PQQ-like domain PQQ_3 PF13570.6 ORY14743.1 - 3.7e-06 27.2 15.9 0.33 11.5 0.2 7.2 8 0 0 8 8 8 3 PQQ-like domain PQQ PF01011.21 ORY14743.1 - 4.8e-06 26.2 0.5 0.63 10.1 0.0 3.9 3 0 0 3 3 3 2 PQQ enzyme repeat DUF2867 PF11066.8 ORY14746.1 - 0.045 14.1 0.1 0.071 13.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2867) DUF2635 PF10948.8 ORY14746.1 - 0.12 12.1 0.1 0.25 11.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2635) HET PF06985.11 ORY14747.1 - 8.1e-14 52.2 0.2 1.1e-13 51.7 0.2 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DbpA PF03880.15 ORY14750.1 - 0.0054 16.7 0.5 0.017 15.1 0.0 2.1 2 0 0 2 2 2 1 DbpA RNA binding domain RRM_1 PF00076.22 ORY14750.1 - 0.068 13.0 0.0 0.17 11.7 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SepZ PF06066.11 ORY14750.1 - 0.11 12.7 0.1 0.27 11.5 0.1 1.6 1 0 0 1 1 1 0 SepZ Cons_hypoth698 PF03601.14 ORY14751.1 - 0.019 13.9 0.0 0.056 12.3 0.0 1.6 2 0 0 2 2 2 0 Conserved hypothetical protein 698 COX14 PF14880.6 ORY14752.1 - 3e-18 65.4 1.2 2e-17 62.7 0.1 2.5 2 0 0 2 2 2 1 Cytochrome oxidase c assembly DUF5084 PF16894.5 ORY14752.1 - 0.013 15.9 0.0 0.019 15.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5084) NnrU PF07298.11 ORY14752.1 - 0.054 13.0 0.2 0.1 12.1 0.2 1.4 1 0 0 1 1 1 0 NnrU protein DUF2458 PF10454.9 ORY14753.1 - 4.1e-43 147.0 6.4 1.6e-42 145.0 6.4 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF2458) MRP-S27 PF10037.9 ORY14753.1 - 0.076 11.9 2.5 0.12 11.2 2.5 1.2 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 NolB PF17398.2 ORY14753.1 - 0.091 13.2 0.1 0.18 12.2 0.1 1.4 1 0 0 1 1 1 0 Nodulation protein NolB Snurportin1 PF11538.8 ORY14753.1 - 0.092 13.0 3.9 0.2 11.8 3.9 1.6 1 0 0 1 1 1 0 Snurportin1 Pterin_4a PF01329.19 ORY14754.1 - 1.6e-25 89.1 0.3 1.7e-25 89.0 0.3 1.0 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase bZIP_1 PF00170.21 ORY14757.1 - 2.2e-10 40.5 9.2 8.3e-10 38.6 9.2 1.8 1 1 0 1 1 1 1 bZIP transcription factor MSA-2c PF12238.8 ORY14757.1 - 0.0084 16.1 0.8 0.0084 16.1 0.8 2.0 2 0 0 2 2 2 1 Merozoite surface antigen 2c bZIP_2 PF07716.15 ORY14757.1 - 0.028 14.5 10.6 0.11 12.6 6.7 2.2 1 1 1 2 2 2 0 Basic region leucine zipper BHD_2 PF10404.9 ORY14757.1 - 0.12 13.3 1.4 0.3 12.1 1.4 1.6 1 0 0 1 1 1 0 Rad4 beta-hairpin domain 2 Imm32 PF15566.6 ORY14757.1 - 0.13 12.1 0.0 1.5 8.7 0.0 2.3 2 0 0 2 2 2 0 Immunity protein 32 FtsX PF02687.21 ORY14758.1 - 0.15 12.5 4.3 0.25 11.8 4.3 1.3 1 0 0 1 1 1 0 FtsX-like permease family Cyto_heme_lyase PF01265.17 ORY14759.1 - 3.4e-116 387.9 0.0 4e-116 387.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase Yip1 PF04893.17 ORY14760.1 - 8.8e-08 32.1 12.9 1.7e-07 31.1 12.9 1.5 1 1 0 1 1 1 1 Yip1 domain F-box-like PF12937.7 ORY14761.1 - 0.017 15.0 0.1 0.16 11.9 0.0 2.7 2 0 0 2 2 2 0 F-box-like FlhC PF05280.11 ORY14761.1 - 1 9.0 6.3 2 8.1 6.3 1.4 1 0 0 1 1 1 0 Flagellar transcriptional activator (FlhC) AZUL PF16558.5 ORY14762.1 - 5.5e-08 32.9 0.3 3.2e-07 30.5 0.0 2.3 2 0 0 2 2 2 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A Pkinase PF00069.25 ORY14763.1 - 1.4e-62 211.5 0.0 2.1e-62 210.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY14763.1 - 5.9e-30 104.4 0.0 1e-29 103.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 ORY14763.1 - 0.0075 15.3 0.1 0.0075 15.3 0.1 1.6 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 ORY14763.1 - 0.041 13.2 0.1 0.041 13.2 0.1 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Plasmodium_Vir PF05795.11 ORY14763.1 - 0.051 13.0 0.3 0.079 12.4 0.3 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein LCD1 PF09798.9 ORY14763.1 - 0.053 12.0 1.0 0.071 11.6 1.0 1.2 1 0 0 1 1 1 0 DNA damage checkpoint protein Kinase-like PF14531.6 ORY14763.1 - 0.16 11.3 0.1 0.16 11.3 0.1 1.9 2 1 0 2 2 2 0 Kinase-like RIO1 PF01163.22 ORY14763.1 - 0.16 11.6 0.0 0.16 11.6 0.0 1.9 2 0 0 2 2 2 0 RIO1 family APH PF01636.23 ORY14763.1 - 0.18 11.7 0.1 0.18 11.7 0.1 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family Rrn6 PF10214.9 ORY14763.1 - 1.1 7.7 3.9 1.4 7.4 3.9 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DUF4193 PF13834.6 ORY14763.1 - 3.2 8.3 5.1 6.4 7.3 5.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4193) DUF4554 PF15091.6 ORY14763.1 - 7.2 5.4 6.6 11 4.8 6.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) Methyltransf_28 PF02636.17 ORY14764.1 - 6e-75 252.3 0.0 7.3e-75 252.0 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase RRM_1 PF00076.22 ORY14765.1 - 1.8e-14 53.3 0.0 2.5e-14 52.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 ORY14765.1 - 0.0058 16.2 0.0 0.0091 15.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 ORY14765.1 - 0.018 15.1 0.0 0.029 14.4 0.0 1.2 1 0 0 1 1 1 0 RNA binding motif RRM_occluded PF16842.5 ORY14765.1 - 0.051 13.4 0.0 0.085 12.7 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif RAP1 PF07218.11 ORY14765.1 - 0.49 8.6 3.3 0.74 8.0 3.3 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Profilin PF00235.19 ORY14766.1 - 5.8e-43 146.2 0.8 6.4e-43 146.1 0.8 1.0 1 0 0 1 1 1 1 Profilin HeLo PF14479.6 ORY14767.1 - 3.8e-39 134.6 1.8 6.7e-39 133.9 1.8 1.4 1 0 0 1 1 1 1 Prion-inhibition and propagation Pkinase PF00069.25 ORY14767.1 - 4.4e-06 26.2 0.0 9.8e-06 25.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY14767.1 - 0.068 12.5 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein tyrosine kinase Metallophos PF00149.28 ORY14768.1 - 2.5e-13 51.0 0.6 6.2e-13 49.7 0.6 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 ORY14768.1 - 1.1e-06 28.9 2.1 1.5e-05 25.3 2.1 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Ribosomal_S11 PF00411.19 ORY14769.1 - 3.8e-46 156.0 1.8 4.9e-46 155.7 1.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 PDH PF02153.17 ORY14770.1 - 6.9e-16 58.0 0.1 1.6e-15 56.9 0.1 1.6 2 0 0 2 2 2 1 Prephenate dehydrogenase Cyclin PF08613.11 ORY14772.1 - 4.8e-09 36.8 0.0 8.2e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Cyclin Lactamase_B_2 PF12706.7 ORY14773.1 - 5.9e-27 94.5 0.0 7.6e-26 90.9 0.0 2.3 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 ORY14773.1 - 9.5e-11 41.9 0.0 3.3e-10 40.1 0.0 1.9 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 ORY14773.1 - 0.0027 17.7 5.5 2.9 7.9 3.8 3.2 3 0 0 3 3 3 2 Metallo-beta-lactamase superfamily Ribosomal_L30_N PF08079.12 ORY14774.1 - 3e-27 94.7 20.4 3e-27 94.7 20.4 1.9 2 0 0 2 2 2 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 ORY14774.1 - 1.1e-18 66.8 2.0 2.2e-18 65.9 2.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e CSRNP_N PF16019.5 ORY14774.1 - 0.011 15.6 4.0 0.017 15.0 4.0 1.2 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus Tipalpha PF16753.5 ORY14774.1 - 0.028 14.3 0.6 0.18 11.6 0.1 2.1 1 1 1 2 2 2 0 TNF-alpha-Inducing protein of Helicobacter FRG1 PF06229.12 ORY14774.1 - 0.25 11.0 6.3 0.43 10.3 6.3 1.3 1 0 0 1 1 1 0 FRG1-like domain CFEM PF05730.11 ORY14776.1 - 0.0063 16.6 3.5 0.012 15.7 3.5 1.5 1 0 0 1 1 1 1 CFEM domain Got1 PF04178.12 ORY14777.1 - 1.4e-14 54.5 13.4 1.8e-14 54.1 13.4 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family YL1_C PF08265.11 ORY14778.1 - 1.7e-16 59.6 0.3 3.2e-16 58.8 0.3 1.5 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain DASH_Dad4 PF08650.10 ORY14779.1 - 3.9e-32 110.0 6.6 4.2e-32 109.9 6.6 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad4 GM_CSF PF01109.17 ORY14779.1 - 0.015 15.4 0.4 0.017 15.3 0.4 1.1 1 0 0 1 1 1 0 Granulocyte-macrophage colony-stimulating factor DASH_Dad1 PF08649.10 ORY14779.1 - 0.1 12.8 3.6 0.15 12.3 3.6 1.3 1 0 0 1 1 1 0 DASH complex subunit Dad1 Actin PF00022.19 ORY14780.1 - 4e-49 167.3 0.0 6.2e-25 87.7 0.0 2.3 2 0 0 2 2 2 2 Actin DUF3040 PF11239.8 ORY14780.1 - 0.12 12.7 0.1 0.3 11.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) Herpes_UL32 PF06070.11 ORY14780.1 - 9 3.9 8.3 19 2.8 8.3 1.4 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 Y_phosphatase PF00102.27 ORY14781.1 - 3.2e-59 200.3 0.1 1.9e-31 109.4 0.0 3.0 3 1 0 3 3 3 2 Protein-tyrosine phosphatase Rhodanese PF00581.20 ORY14781.1 - 2.5e-07 31.2 0.0 1.1e-06 29.1 0.0 2.1 2 0 0 2 2 2 1 Rhodanese-like domain DSPc PF00782.20 ORY14781.1 - 0.0033 17.2 0.2 0.0075 16.1 0.2 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 ORY14781.1 - 0.0095 15.9 0.0 0.017 15.1 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family SMC_Nse1 PF07574.13 ORY14782.1 - 5.3e-58 196.1 0.5 6.5e-58 195.8 0.5 1.1 1 0 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.11 ORY14782.1 - 7e-11 42.3 9.5 1.1e-10 41.7 9.5 1.3 1 0 0 1 1 1 1 RING-like domain zf-RING_2 PF13639.6 ORY14782.1 - 0.009 16.3 8.1 0.014 15.8 8.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-ANAPC11 PF12861.7 ORY14782.1 - 0.017 15.1 1.1 0.03 14.4 1.1 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-HC5HC2H_2 PF13832.6 ORY14782.1 - 0.53 10.5 5.3 1.2 9.3 5.3 1.6 1 1 0 1 1 1 0 PHD-zinc-finger like domain C1_2 PF03107.16 ORY14782.1 - 1.7 9.0 5.7 5 7.5 2.9 2.2 2 0 0 2 2 2 0 C1 domain zf-Dof PF02701.15 ORY14782.1 - 1.8 8.8 6.6 1.9 8.7 4.9 2.0 1 1 1 2 2 2 0 Dof domain, zinc finger C1_1 PF00130.22 ORY14782.1 - 2.1 8.3 8.8 0.29 11.1 4.4 1.8 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-HC5HC2H PF13771.6 ORY14782.1 - 2.6 8.4 8.3 7.2 6.9 8.3 1.7 1 1 0 1 1 1 0 PHD-like zinc-binding domain zf-RING_5 PF14634.6 ORY14782.1 - 3.5 7.7 9.0 5.3 7.1 9.0 1.3 1 0 0 1 1 1 0 zinc-RING finger domain DAHP_synth_1 PF00793.20 ORY14784.1 - 1.5e-102 342.2 0.0 1.8e-102 341.9 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family OMPdecase PF00215.24 ORY14784.1 - 0.0044 16.6 0.1 0.012 15.2 0.0 1.8 2 0 0 2 2 2 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Lipase_3 PF01764.25 ORY14786.1 - 9.8e-05 22.2 0.0 0.00018 21.4 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) NUDE_C PF04880.13 ORY14786.1 - 0.0033 17.9 9.3 0.0086 16.6 9.3 1.7 1 0 0 1 1 1 1 NUDE protein, C-terminal conserved region Abhydrolase_6 PF12697.7 ORY14786.1 - 0.069 13.7 2.4 0.089 13.4 0.1 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORY14786.1 - 0.13 11.5 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 VPS9 PF02204.18 ORY14787.1 - 4.3e-27 94.4 0.0 1e-26 93.1 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 ORY14787.1 - 0.017 15.4 0.2 0.21 11.9 0.2 2.8 1 1 0 1 1 1 0 Domain of unknown function (DUF5601) Fungal_TACC PF12709.7 ORY14788.1 - 2.9e-08 34.0 24.9 3.6e-08 33.7 6.2 4.3 4 0 0 4 4 4 2 Fungal Transforming acidic coiled-coil (TACC) proteins PspA_IM30 PF04012.12 ORY14788.1 - 2.8e-06 27.1 11.5 2.8e-06 27.1 11.5 3.3 2 1 1 3 3 3 1 PspA/IM30 family DUF4407 PF14362.6 ORY14788.1 - 1.8e-05 24.2 26.0 0.0036 16.7 6.1 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4407) FPP PF05911.11 ORY14788.1 - 0.00015 20.1 14.7 0.00015 20.1 14.7 2.7 2 1 0 2 2 2 1 Filament-like plant protein, long coiled-coil Tropomyosin_1 PF12718.7 ORY14788.1 - 0.00027 21.1 16.3 0.00027 21.1 16.3 3.9 4 0 0 4 4 4 1 Tropomyosin like Baculo_PEP_C PF04513.12 ORY14788.1 - 0.00083 19.4 2.4 0.82 9.7 0.0 3.6 3 1 1 4 4 4 2 Baculovirus polyhedron envelope protein, PEP, C terminus CENP-F_leu_zip PF10473.9 ORY14788.1 - 0.026 14.5 43.6 0.017 15.2 6.5 3.9 2 1 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF2408 PF10303.9 ORY14788.1 - 0.031 14.9 0.8 0.031 14.9 0.8 3.4 2 1 0 2 2 1 0 Protein of unknown function (DUF2408) DUF745 PF05335.13 ORY14788.1 - 0.43 10.3 34.0 0.024 14.3 16.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF745) WXG100 PF06013.12 ORY14788.1 - 1.2 9.4 13.0 0.29 11.4 0.7 3.9 3 1 1 4 4 4 0 Proteins of 100 residues with WXG HAP1_N PF04849.13 ORY14788.1 - 1.5 8.0 26.1 0.15 11.3 5.6 3.1 3 0 0 3 3 3 0 HAP1 N-terminal conserved region DUF3275 PF11679.8 ORY14788.1 - 1.5 8.7 5.4 0.55 10.2 1.8 2.2 2 0 0 2 2 1 0 Protein of unknown function (DUF3275) Csm1_N PF18504.1 ORY14788.1 - 1.7 9.0 25.3 1.5 9.2 0.7 5.0 4 1 0 4 4 4 0 Csm1 N-terminal domain Filament PF00038.21 ORY14788.1 - 2.7 7.5 39.0 1.1 8.8 3.3 3.1 2 1 0 2 2 2 0 Intermediate filament protein GAS PF13851.6 ORY14788.1 - 4.7 6.5 35.4 0.079 12.3 3.3 3.6 3 1 0 3 3 3 0 Growth-arrest specific micro-tubule binding DUF16 PF01519.16 ORY14788.1 - 8 7.0 20.8 18 5.9 1.1 4.1 3 2 1 4 4 4 0 Protein of unknown function DUF16 CDI PF02234.19 ORY14789.1 - 0.051 13.8 0.4 0.18 12.0 0.4 1.9 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor MFS_1 PF07690.16 ORY14791.1 - 9.3e-22 77.4 79.4 1.5e-17 63.5 44.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4808 PF16066.5 ORY14791.1 - 0.055 14.0 0.1 0.099 13.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4808) HJURP_mid PF12346.8 ORY14791.1 - 0.18 12.2 0.1 0.33 11.4 0.1 1.3 1 0 0 1 1 1 0 Holliday junction recognition protein-associated repeat DUF3431 PF11913.8 ORY14794.1 - 4.7e-13 49.4 0.2 7.1e-06 26.0 0.0 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF3431) HSM3_C PF18794.1 ORY14795.1 - 0.15 11.6 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 DNA mismatch repair protein HSM3, C terminal domain RRM_1 PF00076.22 ORY14798.1 - 0.00036 20.3 0.0 0.00071 19.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Btz PF09405.10 ORY14798.1 - 0.00057 20.1 0.8 0.00098 19.4 0.8 1.4 1 0 0 1 1 1 1 CASC3/Barentsz eIF4AIII binding FGGY_C PF02782.16 ORY14800.1 - 9.2e-52 175.6 0.2 1.6e-51 174.9 0.2 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 ORY14800.1 - 1.5e-24 86.9 1.5 1.4e-22 80.4 1.5 3.0 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.20 ORY14800.1 - 0.00057 19.5 0.1 0.0023 17.5 0.0 1.9 2 0 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family zf-C2H2_9 PF16293.5 ORY14800.1 - 0.095 12.6 0.1 0.3 11.0 0.1 1.8 1 0 0 1 1 1 0 C2H2 type zinc-finger (1 copy) adh_short PF00106.25 ORY14801.1 - 1.1e-40 139.2 0.0 1.4e-40 138.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY14801.1 - 1.1e-28 100.5 0.0 1.3e-28 100.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY14801.1 - 5.9e-08 32.8 0.0 7.7e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 ORY14801.1 - 1.6e-05 24.9 0.6 5.5e-05 23.1 0.2 1.9 1 1 1 2 2 2 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 ORY14801.1 - 0.18 10.9 0.0 0.26 10.4 0.0 1.4 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein Nic96 PF04097.14 ORY14802.1 - 6.5e-194 645.9 0.0 8.7e-194 645.5 0.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 Med27 PF11571.8 ORY14804.1 - 3.2e-13 49.8 0.1 6.1e-13 48.9 0.1 1.4 1 0 0 1 1 1 1 Mediator complex subunit 27 Snf7 PF03357.21 ORY14805.1 - 6.4e-10 38.9 12.0 6.6e-10 38.9 11.6 1.3 1 1 0 1 1 1 1 Snf7 DMSP_lyase PF16867.5 ORY14805.1 - 0.011 15.4 0.3 0.021 14.5 0.0 1.6 2 0 0 2 2 2 0 Dimethlysulfonioproprionate lyase Ist1 PF03398.14 ORY14805.1 - 0.012 15.5 1.2 0.016 15.1 1.2 1.2 1 0 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway CBFD_NFYB_HMF PF00808.23 ORY14806.1 - 3.7e-17 62.4 0.7 7.3e-17 61.4 0.7 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 ORY14806.1 - 0.0001 22.6 0.8 0.00088 19.6 0.0 2.0 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 ORY14806.1 - 0.04 14.0 0.1 0.079 13.0 0.1 1.6 1 1 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit EF-hand_13 PF17958.1 ORY14806.1 - 0.11 12.3 0.0 0.22 11.4 0.0 1.5 1 1 0 1 1 1 0 EF-hand domain Pkinase PF00069.25 ORY14807.1 - 9.5e-69 231.7 0.0 1.3e-68 231.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY14807.1 - 9.1e-31 107.1 0.0 1.3e-30 106.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 ORY14807.1 - 1.4e-11 44.9 0.1 1.4e-11 44.9 0.1 3.0 4 0 0 4 4 4 1 Protein kinase C terminal domain Kinase-like PF14531.6 ORY14807.1 - 5.6e-09 35.7 0.1 3.1e-08 33.3 0.0 1.9 1 1 0 2 2 2 1 Kinase-like C2 PF00168.30 ORY14807.1 - 4.2e-07 30.2 0.0 0.00015 22.0 0.0 2.6 2 0 0 2 2 2 1 C2 domain Haspin_kinase PF12330.8 ORY14807.1 - 0.0015 17.5 0.1 0.0025 16.8 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 ORY14807.1 - 0.0025 17.5 0.2 0.42 10.2 0.1 2.3 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 ORY14807.1 - 0.0075 16.2 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 ORY14807.1 - 0.059 12.7 0.1 0.13 11.6 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Adeno_E3_15_3 PF03307.14 ORY14807.1 - 0.067 13.1 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Adenovirus 15.3kD protein in E3 region MaoC_dehydratas PF01575.19 ORY14808.1 - 8e-22 77.1 0.0 1.5e-21 76.2 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 ORY14808.1 - 0.00013 22.1 0.0 0.0014 18.7 0.0 2.0 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase Peptidase_M28 PF04389.17 ORY14809.1 - 5.7e-35 120.8 0.0 7.9e-35 120.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M28 Amidohydro_1 PF01979.20 ORY14810.1 - 4.5e-19 69.0 0.0 5.8e-19 68.6 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 ORY14810.1 - 9.7e-15 55.0 1.5 1.9e-10 40.8 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Glyco_hydro_3 PF00933.21 ORY14811.1 - 7.8e-66 222.6 0.0 1.1e-65 222.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Acetyltransf_1 PF00583.25 ORY14811.1 - 3.7e-06 27.2 0.0 3.7e-05 24.0 0.0 2.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Glyco_hydro_3_C PF01915.22 ORY14811.1 - 0.001 19.1 0.0 0.0019 18.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Acetyltransf_10 PF13673.7 ORY14811.1 - 0.057 13.4 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain NDT80_PhoG PF05224.12 ORY14813.1 - 2.3e-36 125.8 0.0 4.2e-36 124.9 0.0 1.5 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family Hexokinase_2 PF03727.16 ORY14814.1 - 4.7e-61 206.3 0.0 6.2e-61 205.9 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 ORY14814.1 - 9.9e-45 152.9 0.0 1.6e-44 152.2 0.0 1.3 1 0 0 1 1 1 1 Hexokinase MFS_1 PF07690.16 ORY14817.1 - 3.5e-12 45.9 31.4 4.8e-12 45.5 30.4 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 ORY14817.1 - 1.2e-10 41.3 5.8 1.2e-10 41.3 5.8 2.6 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 MFS_1_like PF12832.7 ORY14817.1 - 0.00041 19.3 5.4 0.00041 19.3 5.4 1.9 2 0 0 2 2 2 1 MFS_1 like family Glucosamine_iso PF01182.20 ORY14818.1 - 3.5e-17 63.0 0.0 5.9e-17 62.3 0.0 1.3 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase OATP PF03137.20 ORY14819.1 - 0.047 12.0 0.1 0.059 11.7 0.1 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family CRAL_TRIO PF00650.20 ORY14820.1 - 5.8e-13 48.9 0.0 1.4e-12 47.6 0.0 1.6 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 ORY14820.1 - 0.00021 21.4 0.0 0.00046 20.3 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 ORY14820.1 - 0.17 12.0 0.0 0.27 11.4 0.0 1.2 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain Pkinase PF00069.25 ORY14822.1 - 9.8e-30 103.8 0.0 1.4e-29 103.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY14822.1 - 4.6e-21 75.3 0.0 7.5e-21 74.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY14822.1 - 0.047 13.0 0.0 0.076 12.3 0.0 1.2 1 0 0 1 1 1 0 Kinase-like FMN_dh PF01070.18 ORY14823.1 - 6.9e-120 400.2 0.0 8.4e-120 399.9 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 ORY14823.1 - 1.7e-22 79.3 0.0 3.8e-22 78.2 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 ORY14823.1 - 4.9e-08 32.5 0.0 9.1e-08 31.6 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 ORY14823.1 - 0.00022 20.4 0.6 0.00042 19.4 0.0 1.7 3 0 0 3 3 3 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 ORY14823.1 - 0.0075 15.7 0.1 0.012 15.1 0.1 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase His_biosynth PF00977.21 ORY14823.1 - 0.061 12.8 0.9 1.2 8.5 0.1 2.3 1 1 0 2 2 2 0 Histidine biosynthesis protein Cytotoxic PF09000.10 ORY14823.1 - 0.091 13.1 0.1 0.24 11.7 0.1 1.7 1 0 0 1 1 1 0 Cytotoxic Pro_CA PF00484.19 ORY14823.1 - 0.17 12.2 0.1 0.38 11.0 0.1 1.5 1 0 0 1 1 1 0 Carbonic anhydrase Ras PF00071.22 ORY14824.1 - 2.5e-42 144.2 0.0 1.7e-39 135.1 0.0 2.0 2 0 0 2 2 2 2 Ras family Roc PF08477.13 ORY14824.1 - 2.8e-34 117.9 0.0 4e-34 117.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY14824.1 - 2e-13 50.2 0.0 3.2e-13 49.5 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 ORY14824.1 - 0.0003 20.8 0.0 0.00054 20.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 ORY14824.1 - 0.00054 19.4 0.0 0.00072 19.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 ORY14824.1 - 0.0015 19.0 0.0 0.0022 18.4 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain SRPRB PF09439.10 ORY14824.1 - 0.012 15.0 0.0 0.018 14.5 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 ORY14824.1 - 0.044 13.7 0.1 0.34 10.8 0.1 2.3 1 1 1 2 2 2 0 RsgA GTPase AAA_24 PF13479.6 ORY14824.1 - 0.053 13.2 0.1 0.11 12.2 0.0 1.6 2 0 0 2 2 2 0 AAA domain RRM_1 PF00076.22 ORY14825.1 - 8.8e-09 35.1 0.0 1.8e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 ORY14825.1 - 4.1e-06 26.7 0.0 8.3e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 ORY14825.1 - 0.00042 20.1 0.0 0.00074 19.3 0.0 1.4 1 0 0 1 1 1 1 Occluded RNA-recognition motif RRM_3 PF08777.11 ORY14825.1 - 0.0024 17.9 0.1 0.0048 16.9 0.1 1.5 1 0 0 1 1 1 1 RNA binding motif NCBP3 PF10309.9 ORY14825.1 - 0.061 13.2 0.1 0.17 11.7 0.1 1.8 1 1 0 1 1 1 0 Nuclear cap-binding protein subunit 3 DUF1386 PF07138.11 ORY14825.1 - 0.11 11.8 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1386) PIR PF00399.19 ORY14826.1 - 0.0011 18.5 0.7 0.0023 17.4 0.7 1.6 1 0 0 1 1 1 1 Yeast PIR protein repeat PGM_PMM_I PF02878.16 ORY14828.1 - 1.4e-19 70.2 0.7 1.3e-09 37.9 0.0 3.1 2 1 1 3 3 3 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 ORY14828.1 - 3.7e-11 43.1 3.0 1.5e-10 41.1 1.7 2.6 3 0 0 3 3 3 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.16 ORY14828.1 - 0.0024 18.0 0.0 0.0071 16.5 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 ORY14828.1 - 0.051 14.2 0.6 0.65 10.7 0.2 3.1 2 1 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II MRP-L28 PF09812.9 ORY14829.1 - 0.00013 22.2 0.0 0.00018 21.7 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 Ras PF00071.22 ORY14830.1 - 1.1e-46 158.4 0.0 1.3e-46 158.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY14830.1 - 4.2e-21 75.4 0.0 6.5e-21 74.8 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY14830.1 - 3.4e-07 29.9 0.0 4.8e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 ORY14830.1 - 0.013 15.0 0.0 0.019 14.4 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 ORY14830.1 - 0.046 13.1 0.0 0.047 13.0 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 ORY14830.1 - 0.062 13.7 0.0 0.11 12.8 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain ADH_zinc_N PF00107.26 ORY14830.1 - 0.13 12.2 0.0 5.7 6.9 0.0 2.3 2 0 0 2 2 2 0 Zinc-binding dehydrogenase AAA_21 PF13304.6 ORY14830.1 - 0.2 11.5 0.0 0.22 11.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system NST1 PF13945.6 ORY14831.1 - 1.8e-58 197.8 0.1 1.8e-58 197.8 0.1 4.9 4 1 1 5 5 5 2 Salt tolerance down-regulator AAA PF00004.29 ORY14832.1 - 3.5e-15 56.6 0.0 8.6e-15 55.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 ORY14832.1 - 0.011 16.2 0.0 0.029 14.8 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.14 ORY14832.1 - 0.015 15.3 0.0 0.03 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 ORY14832.1 - 0.1 12.9 0.4 0.36 11.1 0.1 2.0 1 1 1 2 2 2 0 AAA domain Vps36_ESCRT-II PF11605.8 ORY14832.1 - 0.1 12.8 0.0 0.33 11.2 0.0 1.8 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 DASH_Duo1 PF08651.10 ORY14834.1 - 3.9e-33 113.0 3.4 5.5e-33 112.6 3.4 1.2 1 0 0 1 1 1 1 DASH complex subunit Duo1 TetR_C_24 PF17932.1 ORY14834.1 - 0.17 12.1 3.9 0.52 10.6 0.1 2.1 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain DASH_Dad2 PF08654.10 ORY14834.1 - 0.18 12.3 6.9 0.34 11.3 6.9 1.5 1 1 0 1 1 1 0 DASH complex subunit Dad2 DUF1822 PF08852.11 ORY14834.1 - 0.39 9.7 7.7 0.5 9.4 7.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1822) BRF1 PF07741.13 ORY14834.1 - 0.51 10.7 8.4 0.15 12.4 0.7 2.4 2 1 0 2 2 2 0 Brf1-like TBP-binding domain 7TMR-HDED PF07697.11 ORY14834.1 - 0.8 9.8 10.6 1.3 9.1 10.6 1.3 1 0 0 1 1 1 0 7TM-HD extracellular 3HCDH_N PF02737.18 ORY14834.1 - 0.88 9.4 6.0 0.12 12.3 0.8 1.9 1 1 1 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF1764 PF08576.10 ORY14834.1 - 1.6 9.7 4.5 20 6.2 0.1 2.5 2 1 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) DUF745 PF05335.13 ORY14834.1 - 6.4 6.5 19.5 22 4.7 19.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF745) GalKase_gal_bdg PF10509.9 ORY14835.1 - 9.8e-21 73.1 0.0 2e-20 72.0 0.0 1.6 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.13 ORY14835.1 - 1.1e-15 57.7 0.0 3.5e-15 56.1 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 ORY14835.1 - 3.7e-13 49.5 1.3 9.8e-13 48.1 1.3 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain ABC_tran PF00005.27 ORY14837.1 - 2.2e-25 89.8 0.0 6.1e-25 88.3 0.0 1.8 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 ORY14837.1 - 3.6e-20 72.7 3.2 7e-20 71.8 3.2 1.5 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_22 PF13401.6 ORY14837.1 - 0.00068 19.9 0.0 0.0037 17.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 ORY14837.1 - 0.0028 17.1 0.3 0.087 12.2 0.3 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain FtsK_SpoIIIE PF01580.18 ORY14837.1 - 0.0061 15.9 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_23 PF13476.6 ORY14837.1 - 0.0081 16.7 0.0 0.015 15.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 ORY14837.1 - 0.012 15.3 0.6 0.12 12.2 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF87 PF01935.17 ORY14837.1 - 0.013 15.6 0.2 0.027 14.5 0.2 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain RsgA_GTPase PF03193.16 ORY14837.1 - 0.013 15.4 0.0 0.038 13.9 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase AIG1 PF04548.16 ORY14837.1 - 0.019 14.3 0.2 0.043 13.1 0.2 1.6 1 0 0 1 1 1 0 AIG1 family Zeta_toxin PF06414.12 ORY14837.1 - 0.028 13.7 0.0 0.054 12.8 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin T2SSE PF00437.20 ORY14837.1 - 0.03 13.4 0.0 0.055 12.5 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein UL41A PF17591.2 ORY14837.1 - 0.057 13.5 0.2 0.77 9.9 0.2 2.5 2 0 0 2 2 2 0 Herpesvirus UL41A AAA_16 PF13191.6 ORY14837.1 - 0.057 13.8 0.2 0.14 12.5 0.2 1.8 1 1 0 1 1 1 0 AAA ATPase domain SRP54 PF00448.22 ORY14837.1 - 0.078 12.6 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain MMR_HSR1 PF01926.23 ORY14837.1 - 0.092 12.8 0.0 0.28 11.3 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_7 PF12775.7 ORY14837.1 - 0.13 11.8 0.1 0.25 10.8 0.1 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Sigma54_activat PF00158.26 ORY14837.1 - 0.15 11.8 0.1 0.51 10.0 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_18 PF13238.6 ORY14837.1 - 0.17 12.5 0.0 0.4 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain p450 PF00067.22 ORY14838.1 - 3.1e-51 174.6 0.0 4.4e-51 174.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Glycos_transf_2 PF00535.26 ORY14839.1 - 6.4e-34 117.2 0.0 7.6e-34 117.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 ORY14839.1 - 3.9e-13 49.8 0.0 5.5e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 ORY14839.1 - 5.9e-05 22.7 0.0 7.8e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 ORY14839.1 - 0.00019 21.0 0.0 0.0003 20.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 21 Hydrolase PF00702.26 ORY14840.1 - 0.081 13.2 0.0 0.096 13.0 0.0 1.0 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Metallophos PF00149.28 ORY14858.1 - 2.6e-12 47.7 0.1 4.9e-12 46.8 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 ORY14858.1 - 6.6e-07 29.7 0.0 0.00052 20.2 0.0 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain DnaJ PF00226.31 ORY14860.1 - 1.1e-19 70.3 0.7 2.2e-19 69.3 0.7 1.6 1 0 0 1 1 1 1 DnaJ domain Pkinase PF00069.25 ORY14862.1 - 3.9e-58 196.9 0.2 5.5e-58 196.4 0.2 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY14862.1 - 3e-22 79.2 0.0 4.8e-22 78.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY14862.1 - 9e-06 25.2 0.0 1.5e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 ORY14862.1 - 1e-05 24.7 0.1 1.7e-05 24.0 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 ORY14862.1 - 0.00057 19.3 0.1 0.00097 18.5 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 ORY14862.1 - 0.00091 18.1 0.0 0.0018 17.2 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 ORY14862.1 - 0.0015 18.2 0.1 0.0034 17.0 0.1 1.5 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 ORY14862.1 - 0.0023 17.9 0.2 0.13 12.2 0.1 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family DUF2514 PF10721.9 ORY14864.1 - 0.15 12.1 1.2 0.17 11.9 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) HET PF06985.11 ORY14866.1 - 2.1e-29 102.7 0.1 1.5e-26 93.5 0.0 2.2 2 0 0 2 2 2 2 Heterokaryon incompatibility protein (HET) Prok-E2_B PF14461.6 ORY14866.1 - 0.085 12.6 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B P16-Arc PF04699.14 ORY14869.1 - 6.5e-40 137.0 0.0 8e-40 136.7 0.0 1.1 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) HET PF06985.11 ORY14870.1 - 4.9e-33 114.5 0.3 1.5e-32 112.9 0.3 1.8 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.7 ORY14873.1 - 3.7e-19 69.1 0.0 9e-11 42.2 0.0 3.9 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY14873.1 - 1.4e-11 44.6 0.6 0.012 16.1 0.0 5.3 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 ORY14873.1 - 2.5e-10 40.3 0.9 0.021 15.2 0.1 4.8 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 ORY14873.1 - 5.3e-10 38.7 3.1 0.14 12.8 0.0 6.8 8 0 0 8 8 8 2 Ankyrin repeat Ank_5 PF13857.6 ORY14873.1 - 1.4e-05 25.2 0.7 0.0085 16.4 0.0 4.2 5 1 1 6 6 6 2 Ankyrin repeats (many copies) Scs3p PF10261.9 ORY14874.1 - 2.1e-74 250.1 4.0 2.7e-74 249.8 4.0 1.1 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM GDE_C PF06202.14 ORY14876.1 - 0.0033 16.4 0.0 0.3 10.0 0.0 2.5 2 1 0 2 2 2 2 Amylo-alpha-1,6-glucosidase SesA PF17107.5 ORY14877.1 - 0.041 14.1 0.0 0.13 12.5 0.0 1.8 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases DUF2712 PF10916.8 ORY14877.1 - 0.098 13.3 0.0 0.23 12.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2712) Dala_Dala_lig_C PF07478.13 ORY14877.1 - 0.2 11.2 0.0 0.35 10.4 0.0 1.3 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus DIOX_N PF14226.6 ORY14878.1 - 7.7e-17 62.1 0.0 1.3e-16 61.4 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 ORY14878.1 - 3.7e-15 56.2 0.0 9.1e-15 55.0 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Sugar_tr PF00083.24 ORY14879.1 - 2.5e-15 56.3 19.5 3.3e-15 55.9 13.7 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter PX PF00787.24 ORY14881.1 - 2.8e-13 49.8 0.0 5.7e-13 48.8 0.0 1.5 1 0 0 1 1 1 1 PX domain Lipase_GDSL_2 PF13472.6 ORY14882.1 - 3.2e-14 53.7 0.1 4.6e-14 53.2 0.1 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 ORY14882.1 - 1.5e-08 34.8 0.1 2.2e-08 34.3 0.1 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 ORY14882.1 - 0.0012 19.0 0.0 0.0018 18.4 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family 2OG-FeII_Oxy_2 PF13532.6 ORY14883.1 - 1.2e-11 45.2 0.0 8.4e-09 35.9 0.0 2.2 1 1 1 2 2 2 2 2OG-Fe(II) oxygenase superfamily F-box-like PF12937.7 ORY14884.1 - 8.7e-12 44.7 0.1 1.8e-11 43.8 0.1 1.6 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.6 ORY14884.1 - 3e-11 42.4 16.1 0.00083 19.2 0.0 8.5 10 0 0 10 10 10 3 Leucine Rich repeat F-box PF00646.33 ORY14884.1 - 5.8e-09 35.6 0.2 1.6e-08 34.2 0.2 1.8 1 0 0 1 1 1 1 F-box domain LRR_4 PF12799.7 ORY14884.1 - 0.00097 19.5 12.1 0.15 12.5 0.1 5.9 5 2 2 7 7 7 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY14884.1 - 0.0014 18.9 13.9 2.8 8.8 0.0 6.8 7 0 0 7 7 7 2 Leucine Rich Repeat PRANC PF09372.10 ORY14884.1 - 0.053 13.8 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 PRANC domain HCO3_cotransp PF00955.21 ORY14885.1 - 3e-73 247.4 15.3 8.6e-40 137.0 7.2 2.1 1 1 1 2 2 2 2 HCO3- transporter family DEAD PF00270.29 ORY14886.1 - 1.7e-40 138.6 0.0 4.5e-40 137.3 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY14886.1 - 1.3e-28 99.5 0.0 4.4e-28 97.8 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SET PF00856.28 ORY14886.1 - 9.3e-08 32.6 0.0 1.2e-06 29.0 0.0 2.3 1 1 1 2 2 2 1 SET domain ResIII PF04851.15 ORY14886.1 - 0.00021 21.3 0.0 0.00041 20.4 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 ORY14886.1 - 0.009 14.8 0.0 0.015 14.1 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF4748 PF15932.5 ORY14886.1 - 0.031 14.0 0.4 0.079 12.7 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4748) DUF3244 PF11589.8 ORY14887.1 - 0.0085 16.2 0.0 0.014 15.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3244) Med10 PF09748.9 ORY14889.1 - 2.6e-35 121.0 0.9 2.9e-35 120.9 0.9 1.0 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex DUF3877 PF12993.7 ORY14889.1 - 0.0038 17.1 0.0 0.0041 17.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function, E. rectale Gene description (DUF3877) Snapin_Pallidin PF14712.6 ORY14889.1 - 0.013 15.9 1.7 0.14 12.6 0.2 2.9 2 1 1 3 3 3 0 Snapin/Pallidin NEMO PF11577.8 ORY14889.1 - 0.021 14.8 0.4 0.12 12.4 0.0 2.1 2 0 0 2 2 2 0 NF-kappa-B essential modulator NEMO Flagellin_N PF00669.20 ORY14889.1 - 0.068 13.3 0.4 0.16 12.1 0.1 1.6 2 0 0 2 2 2 0 Bacterial flagellin N-terminal helical region PXA PF02194.15 ORY14890.1 - 3.6e-46 157.4 1.0 6.6e-46 156.6 1.0 1.5 1 0 0 1 1 1 1 PXA domain MMR_HSR1_Xtn PF16897.5 ORY14893.1 - 8.9e-40 135.0 0.9 3.2e-39 133.2 0.3 2.1 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 ORY14893.1 - 9.8e-22 77.2 0.0 3.7e-21 75.3 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase TGS PF02824.21 ORY14893.1 - 2.2e-17 62.8 0.0 6.7e-15 54.9 0.0 2.5 1 1 0 1 1 1 1 TGS domain FeoB_N PF02421.18 ORY14893.1 - 3.8e-10 39.5 0.1 1.7e-09 37.4 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 ORY14893.1 - 0.00016 21.8 0.1 0.039 14.0 0.0 2.4 1 1 1 2 2 2 2 Dynamin family GTP_EFTU PF00009.27 ORY14893.1 - 0.00069 19.2 0.1 9.8 5.7 0.0 4.1 2 2 1 3 3 3 2 Elongation factor Tu GTP binding domain MeaB PF03308.16 ORY14893.1 - 0.0091 15.0 0.1 0.021 13.8 0.1 1.6 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Arf PF00025.21 ORY14893.1 - 0.029 13.8 0.2 2.4 7.6 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family RsgA_GTPase PF03193.16 ORY14893.1 - 0.041 13.8 0.6 4.1 7.3 0.1 3.2 2 1 1 3 3 3 0 RsgA GTPase CDO_I PF05995.12 ORY14894.1 - 6e-44 149.3 0.2 7.1e-44 149.1 0.2 1.1 1 0 0 1 1 1 1 Cysteine dioxygenase type I PCO_ADO PF07847.12 ORY14894.1 - 1.7e-05 24.4 0.5 2.8e-05 23.7 0.5 1.5 1 1 0 1 1 1 1 PCO_ADO Glyco_transf_90 PF05686.12 ORY14895.1 - 1.1e-09 37.7 6.7 1.1e-05 24.5 4.8 4.1 2 1 0 2 2 2 2 Glycosyl transferase family 90 Vac_ImportDeg PF09783.9 ORY14896.1 - 2.1e-32 112.2 0.2 3e-19 69.4 0.0 2.3 2 0 0 2 2 2 2 Vacuolar import and degradation protein p450 PF00067.22 ORY14899.1 - 1.4e-64 218.6 0.0 1.7e-64 218.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Pyridox_ox_2 PF12900.7 ORY14901.1 - 8.2e-39 132.8 0.0 1e-38 132.5 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF1772 PF08592.11 ORY14904.1 - 1.9e-31 109.2 6.9 2.5e-31 108.8 6.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) Abhydrolase_1 PF00561.20 ORY14905.1 - 1.5e-14 54.2 0.1 9.9e-09 35.2 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORY14905.1 - 4.9e-14 53.5 0.0 8.1e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORY14905.1 - 7.5e-05 22.1 0.0 0.00066 19.0 0.0 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 IDO PF01231.18 ORY14906.1 - 2.2e-26 92.6 0.0 2.6e-26 92.4 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase zf-C2H2 PF00096.26 ORY14908.1 - 0.014 15.8 3.3 0.041 14.4 3.3 1.9 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY14908.1 - 0.17 12.4 1.5 8 7.1 0.2 2.5 2 0 0 2 2 2 0 Zinc-finger double domain CFEM PF05730.11 ORY14910.1 - 2.1e-05 24.5 10.4 5.2e-05 23.3 10.4 1.7 1 0 0 1 1 1 1 CFEM domain SARAF PF06682.12 ORY14910.1 - 3.3e-05 23.7 0.4 6.4e-05 22.8 0.4 1.5 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis TMIE PF16038.5 ORY14910.1 - 0.066 13.1 0.2 0.066 13.1 0.2 1.9 2 0 0 2 2 2 0 TMIE protein EVC2_like PF12297.8 ORY14910.1 - 0.19 10.4 0.0 0.29 9.8 0.0 1.2 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein YajC PF02699.15 ORY14910.1 - 0.23 11.4 0.1 0.23 11.4 0.1 2.0 2 0 0 2 2 2 0 Preprotein translocase subunit TFIIA PF03153.13 ORY14910.1 - 2.7 7.9 13.2 3.5 7.5 13.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SnoaL_2 PF12680.7 ORY14911.1 - 0.0036 17.9 0.1 0.005 17.5 0.1 1.2 1 0 0 1 1 1 1 SnoaL-like domain WW PF00397.26 ORY14912.1 - 4.2e-09 36.3 1.3 5.7e-08 32.7 0.1 2.7 2 0 0 2 2 2 1 WW domain EF-hand_7 PF13499.6 ORY14912.1 - 0.00087 19.7 0.1 0.0032 17.9 0.1 2.1 1 0 0 1 1 1 1 EF-hand domain pair DUF4519 PF15012.6 ORY14913.1 - 0.015 15.4 1.4 9.2 6.5 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) DUF4064 PF13273.6 ORY14913.1 - 0.038 14.3 1.1 0.29 11.5 0.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) DUF3671 PF12420.8 ORY14913.1 - 0.31 11.1 1.3 0.51 10.4 0.1 2.0 2 1 0 2 2 2 0 Protein of unknown function Clr5 PF14420.6 ORY14914.1 - 1.2e-16 60.7 5.3 4.6e-15 55.6 4.2 2.7 2 0 0 2 2 2 1 Clr5 domain YqgF PF14639.6 ORY14914.1 - 0.11 12.2 0.0 0.28 11.0 0.0 1.6 1 0 0 1 1 1 0 Holliday-junction resolvase-like of SPT6 IBR PF01485.21 ORY14915.1 - 7e-10 39.0 50.3 1.3e-07 31.8 3.7 4.9 5 0 0 5 5 5 2 IBR domain, a half RING-finger domain FYVE PF01363.21 ORY14915.1 - 0.033 14.3 0.0 0.033 14.3 0.0 5.0 4 1 1 5 5 5 0 FYVE zinc finger Stm1_N PF09598.10 ORY14916.1 - 2.5e-07 31.4 11.4 2.5e-07 31.4 11.4 4.6 4 1 0 4 4 4 1 Stm1 HABP4_PAI-RBP1 PF04774.15 ORY14916.1 - 1.1e-05 26.3 10.3 1.1e-05 26.3 10.3 2.2 2 0 0 2 2 2 1 Hyaluronan / mRNA binding family bZIP_1 PF00170.21 ORY14917.1 - 7e-06 26.0 8.0 7e-06 26.0 8.0 1.6 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 ORY14917.1 - 0.0013 18.8 7.6 0.0031 17.6 7.6 1.6 1 0 0 1 1 1 1 Basic region leucine zipper Mit_KHE1 PF10173.9 ORY14917.1 - 0.036 14.1 0.4 0.063 13.4 0.4 1.4 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related DUF3890 PF13029.6 ORY14917.1 - 0.12 12.8 0.6 0.18 12.2 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3890) Vir_act_alpha_C PF10400.9 ORY14917.1 - 0.24 12.1 3.1 0.52 11.0 3.1 1.5 1 0 0 1 1 1 0 Virulence activator alpha C-term GBP_C PF02841.14 ORY14917.1 - 0.42 10.0 5.6 0.66 9.3 5.6 1.3 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Fib_alpha PF08702.10 ORY14917.1 - 0.83 9.8 5.2 0.32 11.2 2.7 1.5 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family OmpH PF03938.14 ORY14917.1 - 2.3 8.5 7.6 0.13 12.6 1.4 2.0 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) Arrestin_C PF02752.22 ORY14919.1 - 5.7e-12 46.2 0.2 2.2e-11 44.3 0.2 1.9 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 ORY14919.1 - 1.9e-06 28.0 0.2 0.12 12.5 0.0 2.8 2 1 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Fungal_trans PF04082.18 ORY14921.1 - 6.1e-13 48.4 0.0 1.1e-12 47.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY14921.1 - 1.9e-06 27.9 12.1 1.9e-06 27.9 12.1 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ku PF02735.16 ORY14922.1 - 8.6e-33 113.8 0.0 1.4e-32 113.1 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_PK_bind PF08785.11 ORY14922.1 - 1.4e-30 105.9 0.0 2.6e-30 105.0 0.0 1.5 1 0 0 1 1 1 1 Ku C terminal domain like Rotamase_3 PF13616.6 ORY14923.1 - 4.5e-13 49.8 0.0 9.9e-13 48.7 0.0 1.5 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 ORY14923.1 - 4.2e-12 46.9 0.0 5.6e-12 46.5 0.0 1.3 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 ORY14923.1 - 0.0059 17.4 0.0 0.008 17.0 0.0 1.3 1 1 0 1 1 1 1 PPIC-type PPIASE domain Ank_2 PF12796.7 ORY14924.1 - 6.7e-16 58.7 0.0 5.2e-08 33.4 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ORY14924.1 - 1.9e-09 37.6 0.0 3e-05 24.2 0.0 3.6 2 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 ORY14924.1 - 1.6e-08 34.9 0.1 0.011 16.2 0.0 3.8 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 ORY14924.1 - 4.3e-07 30.1 0.7 0.07 13.6 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 ORY14924.1 - 8.3e-07 28.9 0.5 0.96 10.2 0.0 4.3 5 0 0 5 5 5 2 Ankyrin repeat DdrB PF12747.7 ORY14924.1 - 0.2 11.4 2.4 0.58 10.0 0.0 2.8 3 0 0 3 3 3 0 DdrB-like protein Steroid_dh PF02544.16 ORY14925.1 - 8e-16 58.4 2.2 1.3e-15 57.7 2.2 1.4 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF5596 PF18082.1 ORY14925.1 - 0.045 13.6 0.1 0.15 11.9 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5596) Glyco_transf_28 PF03033.20 ORY14926.1 - 1.8e-16 60.4 0.0 5.9e-16 58.8 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 ORY14926.1 - 3.4e-06 26.2 0.0 5.2e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 ORY14926.1 - 0.00058 19.9 0.0 0.0014 18.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain FbpA PF05833.11 ORY14926.1 - 0.054 12.2 0.2 0.11 11.3 0.2 1.3 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) adh_short PF00106.25 ORY14927.1 - 2.5e-34 118.5 0.0 7.1e-33 113.7 0.0 2.2 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY14927.1 - 3.3e-28 98.8 0.0 6.5e-27 94.6 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY14927.1 - 1.4e-09 38.2 0.0 3.4e-06 27.1 0.0 2.2 2 0 0 2 2 2 2 KR domain Epimerase PF01370.21 ORY14927.1 - 0.00024 20.7 0.0 0.0038 16.7 0.0 2.3 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ORY14927.1 - 0.028 13.8 0.0 0.054 12.9 0.0 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 ORY14927.1 - 0.22 10.6 0.0 0.3 10.2 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein HAD PF12710.7 ORY14928.1 - 3.3e-20 73.3 0.0 6.3e-20 72.4 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ORY14928.1 - 2.7e-16 60.5 0.2 7.4e-16 59.1 0.2 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 ORY14928.1 - 6.8e-08 32.6 0.1 4e-07 30.0 0.0 2.2 2 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 ORY14928.1 - 0.0011 18.4 0.0 0.3 10.4 0.0 2.2 2 0 0 2 2 2 2 Putative Phosphatase HAD_2 PF13419.6 ORY14928.1 - 0.0032 17.6 0.1 0.13 12.3 0.1 2.9 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase S6PP PF05116.13 ORY14928.1 - 0.086 12.3 0.0 0.25 10.9 0.0 1.7 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase DUF295 PF03478.18 ORY14931.1 - 0.13 11.8 0.2 0.39 10.3 0.2 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF295) RF-1 PF00472.20 ORY14931.1 - 2.9 7.8 9.1 5.5 6.9 9.1 1.5 1 0 0 1 1 1 0 RF-1 domain F-box-like PF12937.7 ORY14933.1 - 0.0079 16.1 0.5 0.036 14.0 0.1 2.0 2 0 0 2 2 2 1 F-box-like eIF-5_eIF-2B PF01873.17 ORY14934.1 - 7.4e-42 141.9 0.6 1.3e-41 141.2 0.6 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 zf-HYPF PF07503.12 ORY14934.1 - 0.16 11.8 1.8 13 5.7 0.1 2.8 3 0 0 3 3 3 0 HypF finger GET2 PF08690.10 ORY14934.1 - 0.22 11.2 5.0 0.29 10.8 5.0 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 RNA_polI_A34 PF08208.11 ORY14934.1 - 0.35 10.9 18.7 0.62 10.1 18.7 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Arc_trans_TRASH PF08394.10 ORY14934.1 - 1.1 9.7 8.1 1.3 9.5 0.3 2.8 1 1 1 2 2 2 0 Archaeal TRASH domain MARVEL PF01284.23 ORY14936.1 - 0.0039 17.2 12.1 0.0069 16.4 12.1 1.4 1 0 0 1 1 1 1 Membrane-associating domain DUF4149 PF13664.6 ORY14936.1 - 1.5 9.2 6.4 10 6.5 1.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4149) DUF2207 PF09972.9 ORY14936.1 - 4 6.1 4.4 5.4 5.7 0.0 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Hydrolase_4 PF12146.8 ORY14937.1 - 2.3e-08 33.6 0.1 2e-07 30.5 0.1 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 LIP PF03583.14 ORY14937.1 - 7.6e-08 32.0 0.1 1.2e-07 31.4 0.1 1.2 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_6 PF12697.7 ORY14937.1 - 2.2e-07 31.7 0.0 3e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 ORY14937.1 - 2.1e-06 27.3 0.5 0.00054 19.5 0.6 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 ORY14937.1 - 0.0002 21.1 0.0 0.00034 20.3 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.18 ORY14937.1 - 0.00026 20.6 0.4 0.0013 18.3 0.1 2.0 2 0 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 ORY14937.1 - 0.0039 17.0 0.8 0.046 13.5 0.4 2.7 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase Peptidase_S15 PF02129.18 ORY14937.1 - 0.0094 15.6 0.5 0.022 14.4 0.3 1.6 2 1 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) PAF-AH_p_II PF03403.13 ORY14937.1 - 0.018 13.6 0.2 0.055 12.0 0.1 1.7 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II DUF676 PF05057.14 ORY14937.1 - 0.019 14.4 0.0 0.031 13.8 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Abhydrolase_8 PF06259.12 ORY14937.1 - 0.097 12.3 0.1 0.25 10.9 0.1 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase HAD_2 PF13419.6 ORY14938.1 - 1.3e-14 54.6 0.0 3.8e-14 53.2 0.0 1.7 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ORY14938.1 - 5e-10 40.0 0.0 3.3e-06 27.5 0.0 2.4 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ORY14938.1 - 1.2e-05 25.3 0.1 3.7e-05 23.7 0.1 1.8 2 0 0 2 2 2 1 HAD-hyrolase-like HAD PF12710.7 ORY14938.1 - 0.076 13.4 0.0 1.2 9.5 0.0 2.3 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase PALP PF00291.25 ORY14939.1 - 1e-62 212.3 1.0 1.2e-62 212.0 1.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ADH_zinc_N PF00107.26 ORY14939.1 - 0.0053 16.7 0.3 3.5 7.6 0.1 2.3 2 0 0 2 2 2 2 Zinc-binding dehydrogenase Peripla_BP_6 PF13458.6 ORY14939.1 - 0.019 14.6 0.2 0.041 13.5 0.2 1.5 1 0 0 1 1 1 0 Periplasmic binding protein Peptidase_S10 PF00450.22 ORY14940.1 - 1.5e-81 275.0 0.0 1.9e-81 274.7 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Pro-kuma_activ PF09286.11 ORY14941.1 - 2e-40 138.4 0.1 5.7e-40 136.9 0.1 1.8 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 ORY14941.1 - 1.2e-06 28.0 0.2 2.2e-06 27.2 0.2 1.4 1 0 0 1 1 1 1 Subtilase family Ank_2 PF12796.7 ORY14942.1 - 3.3e-32 110.9 7.0 2.9e-13 50.2 0.2 2.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ORY14942.1 - 1.2e-25 89.3 6.4 7.8e-11 42.0 0.0 3.4 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY14942.1 - 1.5e-20 71.0 1.0 2.3e-06 27.5 0.1 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.6 ORY14942.1 - 5.4e-20 71.5 3.1 9e-09 35.7 0.4 3.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 ORY14942.1 - 6.3e-20 70.7 3.8 3.5e-06 27.2 0.1 4.1 4 0 0 4 4 4 4 Ankyrin repeat NACHT PF05729.12 ORY14943.1 - 7e-06 26.1 0.0 9.9e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 ORY14943.1 - 7.1e-05 23.1 0.0 0.00013 22.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 ORY14943.1 - 0.0047 17.3 0.0 0.0088 16.4 0.0 1.4 1 0 0 1 1 1 1 RNA helicase AAA_16 PF13191.6 ORY14943.1 - 0.014 15.7 0.0 0.025 15.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain HET PF06985.11 ORY14944.1 - 2e-37 128.8 0.3 4.6e-37 127.6 0.2 1.7 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) FAD_binding_4 PF01565.23 ORY14945.1 - 1.3e-11 44.4 0.0 2.9e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain AIM24 PF01987.17 ORY14946.1 - 1.3e-45 155.7 1.2 1.5e-45 155.5 1.2 1.0 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 SMP PF04927.12 ORY14949.1 - 0.00014 22.3 4.1 0.8 10.2 0.4 4.1 3 1 1 4 4 4 3 Seed maturation protein DUF4552 PF15089.6 ORY14949.1 - 0.19 10.7 2.6 0.21 10.6 1.7 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4552) Aldo_ket_red PF00248.21 ORY14950.1 - 8.1e-66 222.2 0.0 1e-65 221.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Glyco_transf_8 PF01501.20 ORY14951.1 - 4.1e-23 82.3 1.4 2.4e-22 79.8 1.4 2.0 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 ORY14951.1 - 0.015 14.6 0.0 0.023 14.1 0.0 1.2 1 0 0 1 1 1 0 Mannosyltransferase putative Nucleotid_trans PF03407.16 ORY14951.1 - 0.029 14.4 0.2 0.063 13.2 0.2 1.5 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase AA_permease_N PF08403.10 ORY14951.1 - 0.078 12.5 0.1 0.24 10.9 0.0 1.9 2 0 0 2 2 2 0 Amino acid permease N-terminal Peptidase_M20 PF01546.28 ORY14952.1 - 3e-33 115.3 0.1 4e-33 114.9 0.1 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 ORY14952.1 - 6.8e-13 48.5 0.0 1.2e-12 47.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain MRP-L20 PF12824.7 ORY14953.1 - 9.1e-55 185.3 7.4 1.1e-54 185.0 7.4 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Neugrin PF06413.11 ORY14953.1 - 4.4e-05 23.6 0.2 9.1e-05 22.6 0.2 1.6 1 0 0 1 1 1 1 Neugrin LCE PF14672.6 ORY14953.1 - 0.091 13.4 1.3 0.18 12.4 1.3 1.5 1 0 0 1 1 1 0 Late cornified envelope VCBS PF13517.6 ORY14954.1 - 9.5e-18 64.6 31.7 2.1e-07 31.4 0.1 7.1 5 2 2 7 7 7 5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Lipase_GDSL_2 PF13472.6 ORY14954.1 - 8.3e-08 32.8 0.1 2e-07 31.6 0.1 1.7 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family FG-GAP PF01839.23 ORY14954.1 - 7.2e-06 26.0 18.1 0.0054 16.8 0.3 5.1 5 0 0 5 5 5 2 FG-GAP repeat TcdB_toxin_midN PF12256.8 ORY14954.1 - 1.7e-05 24.3 1.9 0.55 9.6 0.0 4.2 2 1 2 4 4 4 2 Insecticide toxin TcdB middle/N-terminal region DUF3688 PF12461.8 ORY14954.1 - 0.066 11.7 0.4 0.18 10.2 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3688) Lipase_GDSL PF00657.22 ORY14954.1 - 0.085 12.8 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase Dockerin_1 PF00404.18 ORY14954.1 - 3.8 7.8 12.8 13 6.1 0.0 4.7 5 0 0 5 5 5 0 Dockerin type I domain Alpha_kinase PF02816.18 ORY14955.1 - 1e-50 172.4 0.0 1.6e-50 171.8 0.0 1.3 1 0 0 1 1 1 1 Alpha-kinase family VWA_2 PF13519.6 ORY14955.1 - 1.7e-12 47.9 0.0 4.6e-12 46.5 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 ORY14955.1 - 3.9e-05 24.0 0.0 6.8e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain LMBR1 PF04791.16 ORY14956.1 - 2.4e-123 412.8 6.9 2.8e-123 412.6 6.9 1.0 1 0 0 1 1 1 1 LMBR1-like membrane protein DUF3037 PF11236.8 ORY14956.1 - 0.18 12.2 0.3 0.58 10.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3037) Glutaredoxin PF00462.24 ORY14957.1 - 5.4e-19 68.2 0.0 9.1e-19 67.4 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin DUF836 PF05768.14 ORY14957.1 - 0.0033 17.8 0.0 0.0059 17.0 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_2 PF13098.6 ORY14957.1 - 0.01 16.3 0.0 0.023 15.2 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like domain GST_N_3 PF13417.6 ORY14957.1 - 0.052 14.0 0.0 0.085 13.3 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain DSBA PF01323.20 ORY14957.1 - 0.066 13.0 0.3 0.39 10.5 0.2 2.2 2 1 1 3 3 3 0 DSBA-like thioredoxin domain HEAT PF02985.22 ORY14958.1 - 1.1e-39 131.0 17.2 0.02 15.1 0.0 13.4 14 0 0 14 14 14 12 HEAT repeat HEAT_2 PF13646.6 ORY14958.1 - 9.2e-36 122.1 6.7 3.3e-11 43.4 0.0 8.3 3 3 5 8 8 8 8 HEAT repeats HEAT_EZ PF13513.6 ORY14958.1 - 4.9e-12 46.1 7.5 0.21 12.2 0.1 8.9 7 3 3 10 10 10 3 HEAT-like repeat Vac14_Fab1_bd PF12755.7 ORY14958.1 - 5.7e-12 46.1 1.9 0.00087 19.8 0.2 7.4 5 2 5 10 10 10 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 ORY14958.1 - 8.9e-12 45.3 10.5 0.0011 19.0 0.2 6.2 6 1 1 7 7 7 3 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 ORY14958.1 - 2.3e-06 27.7 6.6 0.19 11.9 0.1 4.9 4 1 1 5 5 5 2 Required for nuclear transport of RNA pol II C-terminus 1 Adaptin_N PF01602.20 ORY14958.1 - 9.2e-06 24.5 9.1 0.003 16.2 0.3 4.7 4 1 1 5 5 5 2 Adaptin N terminal region CLASP_N PF12348.8 ORY14958.1 - 0.00073 19.2 1.6 0.27 10.8 0.1 4.2 3 2 1 4 4 4 1 CLASP N terminal Arm PF00514.23 ORY14958.1 - 0.0081 16.2 2.2 2.1 8.5 0.0 4.3 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat DNA_alkylation PF08713.11 ORY14958.1 - 0.024 14.4 0.0 2.4 7.8 0.0 3.1 2 1 1 3 3 3 0 DNA alkylation repair enzyme TetR_C_16 PF17920.1 ORY14958.1 - 0.028 14.7 0.1 6.4 7.1 0.0 3.5 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain M11L PF11099.8 ORY14958.1 - 0.083 13.2 0.1 5.8 7.2 0.0 3.1 2 1 0 2 2 2 0 Apoptosis regulator M11L like Proteasom_PSMB PF10508.9 ORY14958.1 - 0.12 10.9 4.2 3.9 5.9 0.1 2.3 2 0 0 2 2 2 0 Proteasome non-ATPase 26S subunit IFRD PF05004.13 ORY14958.1 - 0.12 11.5 1.8 0.88 8.6 0.1 3.1 4 1 1 5 5 5 0 Interferon-related developmental regulator (IFRD) API5 PF05918.11 ORY14958.1 - 6.9 5.4 6.6 2.8 6.6 0.1 3.4 4 0 0 4 4 4 0 Apoptosis inhibitory protein 5 (API5) AA_permease_2 PF13520.6 ORY14959.1 - 7.4e-60 203.0 24.6 9.2e-60 202.6 24.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ORY14959.1 - 3.6e-21 75.3 16.6 3.6e-21 75.3 16.6 1.9 2 0 0 2 2 2 1 Amino acid permease Phage_Coat_B PF05356.11 ORY14959.1 - 1.1 9.2 5.2 1.2 9.1 0.7 2.6 2 0 0 2 2 2 0 Phage Coat protein B Pkinase PF00069.25 ORY14961.1 - 1e-63 215.2 0.0 1.2e-63 214.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY14961.1 - 5.3e-36 124.2 0.0 8e-36 123.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY14961.1 - 1.3e-06 28.0 0.0 2.1e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 ORY14961.1 - 0.00022 20.1 0.0 0.00033 19.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 ORY14961.1 - 0.027 14.1 0.0 1.8 8.1 0.0 2.6 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 tRNA_synthFbeta PF17759.1 ORY14962.1 - 5.3e-44 150.2 0.0 8.4e-44 149.6 0.0 1.3 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 ORY14962.1 - 2.4e-31 107.8 0.2 1.1e-30 105.7 0.1 2.1 2 0 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 ORY14962.1 - 6.8e-19 68.2 0.0 1.2e-18 67.4 0.0 1.3 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 ORY14962.1 - 1.3e-16 60.6 0.0 1.9e-14 53.7 0.0 2.5 2 0 0 2 2 2 1 tRNA synthetase B5 domain Thioredoxin_13 PF18401.1 ORY14962.1 - 0.17 11.8 0.0 6.1 6.8 0.0 2.4 2 0 0 2 2 2 0 Thioredoxin-like domain NTR2 PF15458.6 ORY14962.1 - 0.2 11.2 0.0 0.34 10.4 0.0 1.2 1 0 0 1 1 1 0 Nineteen complex-related protein 2 AA_permease PF00324.21 ORY14963.1 - 2.6e-132 441.8 38.8 3.2e-132 441.5 38.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ORY14963.1 - 7.2e-40 137.1 39.0 9.7e-40 136.7 39.0 1.1 1 0 0 1 1 1 1 Amino acid permease F-box-like PF12937.7 ORY14966.1 - 0.14 12.1 0.0 0.47 10.4 0.0 2.0 1 0 0 1 1 1 0 F-box-like EB1 PF03271.17 ORY14968.1 - 2e-18 66.4 1.5 3.7e-18 65.5 1.5 1.5 1 0 0 1 1 1 1 EB1-like C-terminal motif Syja_N PF02383.18 ORY14968.1 - 0.039 13.3 0.0 0.039 13.3 0.0 1.1 1 0 0 1 1 1 0 SacI homology domain Suppressor_APC PF11414.8 ORY14968.1 - 0.063 13.4 0.4 0.14 12.2 0.4 1.5 1 1 0 1 1 1 0 Adenomatous polyposis coli tumour suppressor protein DUF2406 PF10295.9 ORY14984.1 - 5.7e-26 91.0 0.4 1.7e-25 89.5 0.4 1.9 1 0 0 1 1 1 1 Uncharacterised protein (DUF2406) Aldedh PF00171.22 ORY14985.1 - 1.1e-137 459.3 0.8 1.3e-137 459.1 0.8 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family GTP_cyclohydro2 PF00925.20 ORY14985.1 - 0.041 13.5 0.0 0.079 12.5 0.0 1.5 1 0 0 1 1 1 0 GTP cyclohydrolase II LuxC PF05893.14 ORY14985.1 - 0.047 12.7 0.0 0.077 12.0 0.0 1.3 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) Calreticulin PF00262.18 ORY14986.1 - 6e-169 561.7 18.9 7.7e-169 561.3 18.9 1.1 1 0 0 1 1 1 1 Calreticulin family VMA21 PF09446.10 ORY14987.1 - 3.1e-14 52.8 13.2 4.4e-14 52.3 13.2 1.2 1 0 0 1 1 1 1 VMA21-like domain SNF2_N PF00176.23 ORY14988.1 - 2e-54 184.6 0.7 3.4e-54 183.9 0.7 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ORY14988.1 - 1.6e-19 70.3 0.0 1e-17 64.5 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY14988.1 - 4.9e-09 36.4 0.0 1.9e-08 34.5 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 ORY14988.1 - 0.001 18.3 0.0 0.002 17.4 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Pox_D5 PF03288.16 ORY14988.1 - 0.021 15.3 0.0 0.053 14.0 0.0 1.7 1 0 0 1 1 1 0 Poxvirus D5 protein-like CBS PF00571.28 ORY14989.1 - 3.7e-09 36.9 0.1 0.0084 16.5 0.0 3.1 2 1 0 2 2 2 2 CBS domain PP2C PF00481.21 ORY14990.1 - 0.00013 21.7 0.0 0.11 12.1 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 ORY14990.1 - 0.0034 17.0 0.0 0.0056 16.3 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 ORY14990.1 - 0.14 12.0 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 Stage II sporulation protein E (SpoIIE) PWI PF01480.17 ORY14992.1 - 1.5e-28 98.9 0.1 2.2e-28 98.3 0.1 1.3 1 0 0 1 1 1 1 PWI domain AAA_18 PF13238.6 ORY14992.1 - 0.01 16.4 0.2 0.76 10.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain API5 PF05918.11 ORY14992.1 - 4.6 5.9 8.7 4.3 6.0 7.7 1.4 1 1 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) FAA_hydrolase PF01557.18 ORY14995.1 - 1.7e-51 175.0 0.0 2e-51 174.7 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family DUF4795 PF16043.5 ORY14996.1 - 0.00016 21.3 18.0 0.00026 20.6 18.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4795) DUF1664 PF07889.12 ORY14996.1 - 0.00038 20.5 16.3 0.054 13.5 0.1 3.2 2 1 1 3 3 3 3 Protein of unknown function (DUF1664) BLOC1_2 PF10046.9 ORY14996.1 - 0.0092 16.3 11.1 0.05 13.9 3.9 3.5 1 1 1 3 3 3 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 ZapB PF06005.12 ORY14996.1 - 0.098 13.1 12.1 1.6 9.2 0.0 3.9 2 1 0 3 3 3 0 Cell division protein ZapB ABC_tran_CTD PF16326.5 ORY14996.1 - 0.2 11.9 18.1 0.077 13.3 1.6 4.0 1 1 0 3 3 3 0 ABC transporter C-terminal domain CENP-F_leu_zip PF10473.9 ORY14996.1 - 0.24 11.4 24.8 1.3 9.0 17.9 2.5 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF724 PF05266.14 ORY14996.1 - 0.29 10.9 23.0 0.13 12.1 11.5 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DUF465 PF04325.13 ORY14996.1 - 0.35 11.0 10.6 0.066 13.3 3.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF465) YabA PF06156.13 ORY14996.1 - 0.36 11.5 14.0 6.4 7.5 0.1 3.9 1 1 2 3 3 3 0 Initiation control protein YabA Tup_N PF08581.10 ORY14996.1 - 0.46 10.8 15.2 2.9 8.3 0.1 4.0 2 1 2 4 4 4 0 Tup N-terminal FH2 PF02181.23 ORY14996.1 - 2.6 7.1 12.8 2.7 7.0 8.4 2.1 1 1 1 2 2 2 0 Formin Homology 2 Domain DUF2730 PF10805.8 ORY14996.1 - 3 8.0 11.6 2 8.5 1.9 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF2730) zf-C4pol PF14260.6 ORY14996.1 - 7.8 7.1 6.8 28 5.3 0.2 3.5 3 2 0 3 3 3 0 C4-type zinc-finger of DNA polymerase delta DUF1771 PF08590.10 ORY14997.1 - 1.2e-14 54.4 12.0 2.8e-14 53.3 12.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) zf-CCCH PF00642.24 ORY14997.1 - 1e-08 34.8 6.5 0.00097 19.0 1.5 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 ORY14997.1 - 2.7e-07 30.4 10.3 1.9e-05 24.6 1.3 2.8 2 1 0 2 2 2 2 Zinc finger domain Smr PF01713.21 ORY14997.1 - 2.2e-06 27.9 0.0 7.7e-06 26.2 0.0 1.9 1 0 0 1 1 1 1 Smr domain zf-CCCH_4 PF18044.1 ORY14997.1 - 1.4e-05 24.7 10.9 0.00031 20.5 0.3 2.9 2 1 0 2 2 2 2 CCCH-type zinc finger zf-CCCH_2 PF14608.6 ORY14997.1 - 0.00022 21.6 10.1 0.021 15.3 0.6 2.4 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 ORY14997.1 - 0.0059 16.8 2.6 0.33 11.2 0.1 2.3 1 1 1 2 2 2 2 Zinc-finger containing family Torus PF16131.5 ORY14997.1 - 0.096 13.4 7.2 0.34 11.6 1.0 2.5 1 1 1 2 2 2 0 Torus domain Kunitz_BPTI PF00014.23 ORY14997.1 - 1.2 9.4 4.7 2.4 8.5 4.7 1.4 1 0 0 1 1 1 0 Kunitz/Bovine pancreatic trypsin inhibitor domain SNARE_assoc PF09335.11 ORY14998.1 - 9.6e-16 58.4 5.4 9.6e-16 58.4 5.4 2.5 2 1 1 3 3 3 1 SNARE associated Golgi protein DUF2970 PF11174.8 ORY14998.1 - 0.019 14.8 0.7 0.019 14.8 0.7 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2970) ATP-synt_E PF05680.12 ORY14998.1 - 0.023 15.0 1.1 0.12 12.7 0.1 2.2 2 0 0 2 2 2 0 ATP synthase E chain LapA_dom PF06305.11 ORY14998.1 - 0.052 13.4 0.1 0.052 13.4 0.1 2.9 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain F-actin_cap_A PF01267.17 ORY14998.1 - 0.061 12.8 0.1 0.095 12.1 0.1 1.2 1 0 0 1 1 1 0 F-actin capping protein alpha subunit Phage_holin_2_4 PF16082.5 ORY14998.1 - 0.14 11.9 1.4 0.35 10.6 0.2 2.3 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like UPF0154 PF03672.13 ORY14998.1 - 0.55 10.3 1.4 7.5 6.7 0.0 2.9 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0154) Nop25 PF09805.9 ORY14998.1 - 1 9.8 6.8 1.5 9.3 6.8 1.2 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) Met_10 PF02475.16 ORY14999.1 - 4.9e-70 235.3 0.0 6e-70 235.0 0.0 1.1 1 0 0 1 1 1 1 Met-10+ like-protein TRM PF02005.16 ORY14999.1 - 0.12 11.6 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase MethyltransfD12 PF02086.15 ORY14999.1 - 0.15 11.7 0.0 0.25 11.0 0.0 1.2 1 0 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase Kinesin PF00225.23 ORY15000.1 - 6.5e-112 373.7 0.0 1.2e-111 372.9 0.0 1.5 1 0 0 1 1 1 1 Kinesin motor domain DUF3694 PF12473.8 ORY15000.1 - 6.1e-43 147.1 0.9 1.5e-42 145.9 0.0 2.2 2 0 0 2 2 2 1 Kinesin protein Kinesin_assoc PF16183.5 ORY15000.1 - 1.7e-37 129.3 0.8 6.3e-31 107.9 0.3 3.8 3 1 1 4 4 3 2 Kinesin-associated Microtub_bd PF16796.5 ORY15000.1 - 2e-24 86.2 0.1 8.5e-24 84.2 0.0 2.2 2 0 0 2 2 2 1 Microtubule binding PH PF00169.29 ORY15000.1 - 2.6e-05 24.7 0.0 0.00014 22.4 0.0 2.2 2 0 0 2 2 2 1 PH domain KIF1B PF12423.8 ORY15000.1 - 0.00062 20.2 1.3 0.00062 20.2 1.3 2.4 2 0 0 2 2 1 1 Kinesin protein 1B UPF0242 PF06785.11 ORY15000.1 - 0.024 14.8 22.3 0.58 10.2 12.9 2.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus FliT PF05400.13 ORY15000.1 - 0.062 14.1 0.0 0.062 14.1 0.0 4.0 4 0 0 4 4 3 0 Flagellar protein FliT DUF4358 PF14270.6 ORY15000.1 - 0.1 12.9 9.2 0.41 11.0 9.2 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4358) AAA_22 PF13401.6 ORY15000.1 - 0.17 12.2 0.8 2 8.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain UPF0061 PF02696.14 ORY15000.1 - 0.93 8.2 8.8 2 7.1 8.8 1.5 1 0 0 1 1 1 0 Uncharacterized ACR, YdiU/UPF0061 family CaM_bdg_C0 PF10562.9 ORY15000.1 - 1.6 8.8 5.5 0.31 11.1 1.0 2.2 2 0 0 2 2 2 0 Calmodulin-binding domain C0 of NMDA receptor NR1 subunit DUF4854 PF16146.5 ORY15000.1 - 4.8 7.6 10.6 2.5 8.5 7.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4854) Peptidase_M9 PF01752.17 ORY15001.1 - 0.077 12.2 0.3 0.11 11.7 0.3 1.2 1 0 0 1 1 1 0 Collagenase Pkinase PF00069.25 ORY15002.1 - 6.2e-61 206.1 0.0 1.1e-39 136.4 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORY15002.1 - 3.7e-28 98.5 0.0 4.3e-21 75.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.24 ORY15002.1 - 6.3e-13 48.9 0.1 1.2e-12 47.9 0.1 1.5 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.6 ORY15002.1 - 5.1e-09 35.8 0.0 1.2e-05 24.8 0.0 2.3 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 ORY15002.1 - 1.6e-05 25.0 0.0 0.0013 18.7 0.1 2.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family PAS_9 PF13426.7 ORY15002.1 - 0.00011 22.4 0.0 0.00033 20.9 0.0 1.8 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 ORY15002.1 - 0.0012 18.9 0.0 0.0038 17.2 0.0 1.9 2 0 0 2 2 2 1 PAS fold Kdo PF06293.14 ORY15002.1 - 0.003 16.9 0.0 0.0068 15.8 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PAS_4 PF08448.10 ORY15002.1 - 0.0043 17.3 0.0 0.015 15.5 0.0 1.9 1 0 0 1 1 1 1 PAS fold Haspin_kinase PF12330.8 ORY15002.1 - 0.0078 15.2 0.1 0.014 14.3 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 ORY15002.1 - 0.06 13.0 0.0 13 5.3 0.0 2.4 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 ORY15002.1 - 0.091 12.3 2.3 0.1 12.2 0.0 2.1 3 0 0 3 3 3 0 RIO1 family Seadorna_VP7 PF07387.11 ORY15002.1 - 0.11 11.5 0.0 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Tox-ART-HYE1 PF15634.6 ORY15002.1 - 0.13 11.6 0.0 0.46 9.8 0.0 1.8 2 0 0 2 2 2 0 HYE1 signature containing ADP-ribosyltransferase Hva1_TUDOR PF11160.8 ORY15004.1 - 4.9e-19 68.3 3.0 4.9e-19 68.3 3.0 2.9 3 0 0 3 3 3 1 Hypervirulence associated proteins TUDOR domain RAP1 PF07218.11 ORY15004.1 - 2 6.6 10.5 2.4 6.3 10.5 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) NB-ARC PF00931.22 ORY15005.1 - 0.17 11.1 0.0 0.17 11.1 0.0 1.1 1 0 0 1 1 1 0 NB-ARC domain TPR_10 PF13374.6 ORY15006.1 - 1.3e-19 69.4 6.6 5.8e-10 38.7 0.6 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 ORY15006.1 - 1.6e-16 60.4 5.6 2.6e-16 59.6 5.6 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 ORY15006.1 - 5e-09 35.6 6.9 1.5e-05 24.6 0.9 2.8 4 0 0 4 4 2 2 Tetratricopeptide repeat TPR_MalT PF17874.1 ORY15006.1 - 9.1e-09 35.1 4.5 1.3e-08 34.6 4.5 1.3 1 0 0 1 1 1 1 MalT-like TPR region TPR_8 PF13181.6 ORY15006.1 - 8.5e-08 31.8 4.1 0.0051 16.9 0.2 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 ORY15006.1 - 3.6e-07 29.7 2.6 0.014 15.4 0.2 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 ORY15006.1 - 4.9e-06 26.2 5.9 0.00067 19.6 0.4 2.9 4 0 0 4 4 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 ORY15006.1 - 1.1e-05 25.8 6.2 0.053 14.4 0.1 2.7 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 ORY15006.1 - 0.00025 21.6 6.8 0.066 13.9 1.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_21 PF09976.9 ORY15006.1 - 0.00041 20.1 4.0 0.085 12.6 0.2 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat-like domain RPN7 PF10602.9 ORY15006.1 - 0.00061 19.5 0.3 0.24 11.1 0.0 2.2 1 1 1 2 2 2 2 26S proteasome subunit RPN7 DUF5113 PF17140.4 ORY15006.1 - 0.0021 17.9 0.6 0.1 12.4 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF5113) TPR_17 PF13431.6 ORY15006.1 - 0.0026 18.0 4.5 0.22 12.0 0.2 2.8 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_4 PF07721.14 ORY15006.1 - 0.0034 17.8 0.0 0.18 12.6 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat DUF4810 PF16068.5 ORY15006.1 - 0.0042 17.6 1.6 0.8 10.3 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4810) SRP68 PF16969.5 ORY15006.1 - 0.0048 15.9 2.0 0.69 8.8 0.2 2.0 1 1 1 2 2 2 2 RNA-binding signal recognition particle 68 TPR_6 PF13174.6 ORY15006.1 - 0.012 16.2 5.4 1.4 9.7 0.6 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 ORY15006.1 - 0.036 14.6 4.5 0.38 11.3 3.9 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat DUF2225 PF09986.9 ORY15006.1 - 0.047 13.4 0.7 0.32 10.7 0.7 1.8 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_3 PF07720.12 ORY15006.1 - 0.092 12.8 0.8 3 7.9 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 ORY15006.1 - 0.18 11.5 10.1 1.5 8.6 1.0 2.9 2 1 1 3 3 3 0 TPR repeat DUF630 PF04783.12 ORY15006.1 - 0.55 10.4 4.4 13 6.0 0.1 2.5 3 0 0 3 3 2 0 Protein of unknown function (DUF630) Glyco_hydro_38N PF01074.22 ORY15007.1 - 7.7e-85 284.8 0.1 7.7e-85 284.8 0.1 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 ORY15007.1 - 4.3e-58 196.9 0.0 1.5e-57 195.2 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 ORY15007.1 - 4.6e-29 100.4 0.0 8.6e-29 99.6 0.0 1.5 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 ORY15007.1 - 1.5e-08 34.6 0.0 7.6e-08 32.4 0.0 2.2 1 1 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain Glyco_hydro_57 PF03065.15 ORY15007.1 - 0.011 15.0 0.0 0.021 14.1 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 GDP_Man_Dehyd PF16363.5 ORY15009.1 - 1.1e-69 235.3 0.0 1.4e-69 235.1 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 ORY15009.1 - 7.2e-54 182.8 0.0 8.8e-54 182.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 ORY15009.1 - 1.6e-21 76.6 0.0 2e-21 76.2 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 ORY15009.1 - 5.3e-21 75.0 0.0 6.3e-20 71.5 0.0 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 ORY15009.1 - 2.7e-19 69.4 0.0 3.3e-19 69.1 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 ORY15009.1 - 1.4e-14 53.9 0.0 5.8e-13 48.6 0.0 2.2 2 0 0 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.6 ORY15009.1 - 0.00053 19.9 0.0 0.00089 19.2 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding p450 PF00067.22 ORY15010.1 - 1.3e-53 182.4 0.0 2.6e-52 178.1 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 Post_transc_reg PF13797.6 ORY15010.1 - 0.033 14.0 0.2 0.083 12.8 0.2 1.6 1 0 0 1 1 1 0 Post-transcriptional regulator DUF3561 PF12084.8 ORY15011.1 - 2.1 8.4 6.4 10 6.2 0.7 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3561) DUF5325 PF17259.2 ORY15011.1 - 4.7 7.2 8.8 20 5.1 0.0 3.7 3 1 0 3 3 3 0 Family of unknown function (DUF5325) AA_permease_2 PF13520.6 ORY15012.1 - 1.8e-54 185.2 45.3 2.3e-54 184.9 45.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ORY15012.1 - 3.9e-27 95.0 36.0 5e-27 94.6 36.0 1.0 1 0 0 1 1 1 1 Amino acid permease YlaH PF14036.6 ORY15012.1 - 0.019 15.3 1.3 0.019 15.3 1.3 3.2 4 0 0 4 4 4 0 YlaH-like protein AWPM-19 PF05512.11 ORY15012.1 - 1.2 9.3 10.7 0.072 13.3 1.5 3.2 2 1 1 3 3 3 0 AWPM-19-like family DUF4064 PF13273.6 ORY15013.1 - 0.13 12.5 0.3 0.13 12.5 0.3 3.1 3 2 0 3 3 3 0 Protein of unknown function (DUF4064) Kelch_5 PF13854.6 ORY15014.1 - 2e-06 27.7 10.9 1.5e-05 24.8 0.1 5.3 6 0 0 6 6 6 1 Kelch motif Kelch_1 PF01344.25 ORY15014.1 - 2e-05 24.1 0.4 1.1 8.8 0.0 5.2 5 0 0 5 5 5 2 Kelch motif Kelch_4 PF13418.6 ORY15014.1 - 0.00017 21.5 11.6 1.2 9.2 0.0 5.9 6 0 0 6 6 6 2 Galactose oxidase, central domain Herpes_gE PF02480.16 ORY15014.1 - 0.0024 16.7 0.0 0.0035 16.2 0.0 1.1 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E Kelch_2 PF07646.15 ORY15014.1 - 0.098 12.7 9.5 9.4 6.4 0.0 5.4 4 1 1 5 5 5 0 Kelch motif Kelch_6 PF13964.6 ORY15014.1 - 0.46 10.9 13.8 4.5 7.7 0.1 4.9 5 0 0 5 5 5 0 Kelch motif Melibiase_2 PF16499.5 ORY15015.1 - 2.4e-15 56.4 0.8 1.6e-07 30.8 0.7 2.2 2 0 0 2 2 2 2 Alpha galactosidase A Glyco_hydro_97 PF10566.9 ORY15015.1 - 0.1 11.9 0.0 0.34 10.2 0.0 1.7 2 0 0 2 2 2 0 Glycoside hydrolase 97 adh_short_C2 PF13561.6 ORY15016.1 - 4e-40 137.8 0.2 4.9e-40 137.6 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY15016.1 - 7.5e-25 87.5 0.3 9.3e-25 87.2 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Peptidase_M20 PF01546.28 ORY15017.1 - 2.9e-18 66.3 0.3 7.4e-18 65.0 0.3 1.6 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 ORY15017.1 - 9.7e-13 48.0 0.0 3.1e-12 46.4 0.0 1.8 1 0 0 1 1 1 1 Peptidase dimerisation domain Rep_fac_C PF08542.11 ORY15019.1 - 5.5e-15 55.6 0.0 1.2e-14 54.5 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.29 ORY15019.1 - 7.1e-12 45.9 0.0 3.1e-11 43.8 0.0 2.2 2 1 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 ORY15019.1 - 4.3e-09 36.4 0.0 0.0017 18.1 0.0 2.4 2 0 0 2 2 2 2 DNA polymerase III, delta subunit Rad17 PF03215.15 ORY15019.1 - 7.7e-08 32.5 0.0 1.3e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_11 PF13086.6 ORY15019.1 - 1e-05 25.5 0.1 4.5e-05 23.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ORY15019.1 - 5.5e-05 23.6 0.2 0.00018 21.9 0.2 2.0 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 ORY15019.1 - 0.00011 22.0 0.0 0.00021 21.1 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 ORY15019.1 - 0.0011 19.2 0.0 0.0027 18.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_assoc_2 PF16193.5 ORY15019.1 - 0.0012 19.1 0.2 0.0045 17.3 0.2 2.0 1 0 0 1 1 1 1 AAA C-terminal domain AAA_23 PF13476.6 ORY15019.1 - 0.0029 18.2 0.0 0.0043 17.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 ORY15019.1 - 0.0032 17.0 0.0 0.0064 16.0 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region DUF815 PF05673.13 ORY15019.1 - 0.0048 16.1 0.0 0.0087 15.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 ORY15019.1 - 0.0071 16.9 0.0 0.25 11.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 ORY15019.1 - 0.022 15.0 0.0 0.063 13.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 ORY15019.1 - 0.026 14.8 0.3 0.073 13.4 0.3 2.1 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 ORY15019.1 - 0.029 13.7 0.0 0.059 12.7 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ResIII PF04851.15 ORY15019.1 - 0.042 13.8 0.0 0.095 12.7 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_24 PF13479.6 ORY15019.1 - 0.046 13.4 0.0 0.14 11.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 ORY15019.1 - 0.14 12.2 0.0 0.38 10.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.6 ORY15019.1 - 0.2 11.4 0.1 2.3 8.0 0.0 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain NPL4 PF05021.15 ORY15020.1 - 3.5e-138 460.1 0.0 4.5e-138 459.8 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.15 ORY15020.1 - 1.5e-68 229.5 0.1 2.7e-68 228.7 0.1 1.4 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.8 ORY15020.1 - 0.018 15.5 0.0 0.04 14.4 0.0 1.6 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Sec66 PF09802.9 ORY15021.1 - 2e-80 268.6 0.9 2.4e-80 268.4 0.9 1.1 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 DUF3848 PF12959.7 ORY15021.1 - 0.0043 17.1 0.5 0.0081 16.2 0.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3848) PEP-utilisers_N PF05524.13 ORY15021.1 - 0.0058 16.8 0.8 0.01 16.0 0.7 1.5 1 1 0 1 1 1 1 PEP-utilising enzyme, N-terminal Sec8_exocyst PF04048.14 ORY15021.1 - 0.032 14.1 0.0 0.047 13.6 0.0 1.3 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain StbA PF06406.11 ORY15021.1 - 0.07 12.3 0.2 1.3 8.2 0.0 2.0 2 0 0 2 2 2 0 StbA protein FUSC PF04632.12 ORY15021.1 - 0.075 11.6 2.8 0.1 11.2 2.8 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family TBCC_N PF16752.5 ORY15021.1 - 0.25 11.8 2.6 0.35 11.3 0.5 2.1 1 1 1 2 2 2 0 Tubulin-specific chaperone C N-terminal domain DUF3844 PF12955.7 ORY15022.1 - 3.8e-35 120.2 1.9 1.1e-34 118.7 2.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3844) Cwf_Cwc_15 PF04889.12 ORY15023.1 - 0.0019 18.0 10.6 0.0029 17.4 10.6 1.2 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein BUD22 PF09073.10 ORY15023.1 - 0.0029 17.0 8.6 0.0029 17.0 8.6 2.0 2 0 0 2 2 2 1 BUD22 NARP1 PF12569.8 ORY15023.1 - 0.035 13.0 5.2 0.049 12.5 5.2 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF4746 PF15928.5 ORY15023.1 - 0.33 10.3 10.7 0.65 9.4 10.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) RPN2_C PF18004.1 ORY15023.1 - 0.57 10.1 5.9 1.4 8.9 5.9 1.6 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain PPL5 PF18168.1 ORY15023.1 - 1.1 8.5 2.9 1.5 8.0 2.9 1.1 1 0 0 1 1 1 0 Prim-pol family 5 Nop14 PF04147.12 ORY15023.1 - 1.2 7.3 15.4 1.6 6.8 15.4 1.1 1 0 0 1 1 1 0 Nop14-like family Afi1 PF07792.12 ORY15023.1 - 1.6 9.3 7.1 2.9 8.4 7.1 1.4 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking CDC27 PF09507.10 ORY15023.1 - 3.2 7.1 22.8 1.8 7.8 4.2 2.1 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 NOA36 PF06524.12 ORY15023.1 - 4.5 6.5 15.6 6.5 6.0 15.6 1.2 1 0 0 1 1 1 0 NOA36 protein NPR3 PF03666.13 ORY15023.1 - 5.9 5.6 6.2 9.3 4.9 6.2 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DNA_pol_phi PF04931.13 ORY15023.1 - 6 4.8 19.3 8.3 4.4 19.3 1.2 1 0 0 1 1 1 0 DNA polymerase phi RXT2_N PF08595.11 ORY15023.1 - 8.3 6.4 10.0 20 5.2 10.0 1.6 1 0 0 1 1 1 0 RXT2-like, N-terminal Prok-RING_2 PF14445.6 ORY15024.1 - 0.011 15.9 0.5 0.019 15.1 0.5 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 2 DUF4690 PF15756.5 ORY15025.1 - 1 10.0 7.8 0.41 11.3 3.0 2.2 2 0 0 2 2 2 0 Small Novel Rich in Cartilage HET PF06985.11 ORY15026.1 - 3.9e-13 50.0 0.1 6.4e-13 49.3 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Podoplanin PF05808.11 ORY15027.1 - 0.0013 18.9 0.8 0.0018 18.4 0.8 1.2 1 0 0 1 1 1 1 Podoplanin CKS PF01111.19 ORY15028.1 - 1e-34 118.6 1.2 1.4e-34 118.1 1.2 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit zf-C2H2_4 PF13894.6 ORY15029.1 - 6.7e-05 23.4 26.6 0.056 14.3 3.5 5.2 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORY15029.1 - 0.0045 17.2 1.6 0.0045 17.2 1.6 2.7 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-BED PF02892.15 ORY15029.1 - 0.026 14.5 2.6 0.09 12.8 0.0 2.9 3 0 0 3 3 3 0 BED zinc finger zf-LITAF-like PF10601.9 ORY15029.1 - 0.057 13.7 6.1 1.5 9.2 0.0 3.1 2 1 0 2 2 2 0 LITAF-like zinc ribbon domain zf-C2H2 PF00096.26 ORY15029.1 - 0.38 11.3 24.7 6.5 7.4 0.3 4.9 4 0 0 4 4 4 0 Zinc finger, C2H2 type Elf1 PF05129.13 ORY15029.1 - 0.46 10.5 3.9 9.3 6.4 0.0 3.3 3 0 0 3 3 3 0 Transcription elongation factor Elf1 like zf-nanos PF05741.13 ORY15029.1 - 1.2 9.5 9.8 0.45 10.8 4.8 2.8 2 0 0 2 2 2 0 Nanos RNA binding domain zf-C2H2_2 PF12756.7 ORY15029.1 - 1.7 9.0 10.0 16 5.9 2.9 3.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Fungal_trans PF04082.18 ORY15030.1 - 1.7e-18 66.6 0.1 2.6e-18 66.0 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY15030.1 - 0.00012 22.2 6.5 0.00019 21.5 6.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zip PF02535.22 ORY15031.1 - 5.2e-52 177.1 2.8 1.7e-51 175.4 2.8 1.7 1 1 0 1 1 1 1 ZIP Zinc transporter Dmrt1 PF12374.8 ORY15032.1 - 3.1 8.3 9.0 0.21 12.0 2.6 2.2 2 0 0 2 2 2 0 Double-sex mab3 related transcription factor 1 Fungal_trans_2 PF11951.8 ORY15033.1 - 3e-11 42.8 2.3 1.8e-10 40.2 1.6 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain ChaC PF04752.12 ORY15034.1 - 1.1e-46 159.2 0.0 1.1e-29 103.7 0.0 2.9 2 1 0 2 2 2 2 ChaC-like protein Sporozoite_P67 PF05642.11 ORY15034.1 - 0.15 10.1 3.5 0.19 9.8 3.5 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen FAD_binding_3 PF01494.19 ORY15035.1 - 2.9e-23 82.7 0.8 2.5e-20 73.0 0.8 3.0 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 ORY15035.1 - 8.8e-05 21.9 0.0 0.00012 21.4 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 ORY15035.1 - 0.00018 20.7 0.4 0.0041 16.2 0.0 2.5 2 1 0 2 2 2 1 Lycopene cyclase protein SE PF08491.10 ORY15035.1 - 0.0081 15.2 0.0 0.012 14.7 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase PX PF00787.24 ORY15038.1 - 9.7e-18 64.2 0.0 1.3e-17 63.8 0.0 1.2 1 0 0 1 1 1 1 PX domain SAS4 PF15460.6 ORY15039.1 - 7.4e-34 115.8 1.3 1.7e-33 114.6 1.3 1.6 1 0 0 1 1 1 1 Something about silencing, SAS, complex subunit 4 CDC45 PF02724.14 ORY15039.1 - 0.11 10.7 1.0 0.15 10.3 1.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Pex14_N PF04695.13 ORY15039.1 - 6.6 7.4 9.5 0.85 10.3 1.9 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region WD40 PF00400.32 ORY15040.1 - 1.2e-23 82.9 13.2 0.0012 19.6 0.4 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.8 ORY15040.1 - 5.2e-06 25.4 4.8 0.0026 16.5 0.2 2.9 1 1 1 3 3 3 2 Nucleoporin Nup120/160 Pkinase PF00069.25 ORY15041.1 - 2.1e-34 119.1 0.0 2.8e-34 118.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY15041.1 - 8.6e-24 84.2 0.0 1.1e-23 83.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF2985 PF11204.8 ORY15042.1 - 6e-27 93.6 4.0 1e-26 92.9 4.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) Acetyltransf_10 PF13673.7 ORY15043.1 - 1.6e-09 37.7 0.0 2.6e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORY15043.1 - 1.6e-08 34.8 0.0 4e-08 33.5 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ORY15043.1 - 6.1e-05 23.4 0.0 0.00011 22.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 ORY15043.1 - 0.011 15.8 0.0 0.022 14.9 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 ORY15043.1 - 0.076 13.0 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase BRI3BP PF14965.6 ORY15044.1 - 1.8 8.0 6.2 0.12 11.9 0.3 2.0 2 1 0 2 2 2 0 Negative regulator of p53/TP53 MerC PF03203.14 ORY15044.1 - 3.5 8.1 12.1 1.9 9.0 1.6 2.3 1 1 0 2 2 2 0 MerC mercury resistance protein AA_permease_2 PF13520.6 ORY15045.1 - 1.8e-49 168.7 43.5 2.3e-49 168.4 43.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ORY15045.1 - 3.3e-21 75.4 30.3 3.3e-21 75.4 30.3 1.7 2 0 0 2 2 2 1 Amino acid permease DUF3328 PF11807.8 ORY15046.1 - 9.8e-38 130.1 0.0 1.2e-37 129.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) MFS_1 PF07690.16 ORY15047.1 - 2e-35 122.4 52.4 1.1e-34 119.9 50.7 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF5337 PF17272.2 ORY15047.1 - 0.097 12.5 6.8 1.9 8.4 1.0 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5337) OATP PF03137.20 ORY15047.1 - 0.51 8.6 21.5 0.38 9.0 14.1 3.4 1 1 2 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Beta-lactamase PF00144.24 ORY15048.1 - 1.4e-19 70.5 1.1 6e-19 68.5 1.1 1.8 1 1 0 1 1 1 1 Beta-lactamase zf-H2C2_2 PF13465.6 ORY15049.1 - 2.8e-14 52.8 8.0 2.5e-08 34.0 0.2 3.7 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.26 ORY15049.1 - 6.3e-13 48.4 11.0 1.2e-06 28.6 2.4 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 ORY15049.1 - 8.5e-09 35.2 5.0 0.00011 22.1 0.3 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_4 PF13894.6 ORY15049.1 - 1.2e-08 35.0 12.0 0.00014 22.4 1.5 3.8 4 0 0 4 4 3 2 C2H2-type zinc finger zf-met PF12874.7 ORY15049.1 - 3.8e-05 23.9 1.4 0.0046 17.3 0.2 3.0 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 ORY15049.1 - 7.6e-05 22.9 0.3 0.031 14.6 0.1 3.0 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 ORY15049.1 - 0.0012 18.5 5.1 0.14 11.9 0.7 3.1 3 0 0 3 3 3 2 zinc-finger C2H2-type Zn_ribbon_recom PF13408.6 ORY15049.1 - 0.013 16.0 0.5 0.013 16.0 0.5 1.7 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain zf-Di19 PF05605.12 ORY15049.1 - 0.016 15.5 1.1 0.032 14.5 1.1 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding LIM PF00412.22 ORY15049.1 - 0.076 13.3 2.3 12 6.3 1.9 2.6 1 1 1 2 2 2 0 LIM domain zf-C2HE PF16278.5 ORY15049.1 - 0.078 13.4 3.3 1.9 9.0 0.4 2.8 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2HC_2 PF13913.6 ORY15049.1 - 0.14 12.0 0.3 0.14 12.0 0.3 3.3 4 0 0 4 4 4 0 zinc-finger of a C2HC-type zf-C2H2_3rep PF18868.1 ORY15049.1 - 1.7 9.4 6.4 2.9 8.6 0.3 3.1 1 1 2 3 3 3 0 Zinc finger C2H2-type, 3 repeats C5HCH PF17982.1 ORY15049.1 - 1.8 8.8 6.2 4.4 7.5 1.5 2.5 1 1 1 2 2 2 0 NSD Cys-His rich domain Aldolase_II PF00596.21 ORY15050.1 - 2.2e-47 161.4 0.0 2.6e-47 161.2 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain DUF3602 PF12223.8 ORY15052.1 - 3.1e-22 79.0 14.1 1e-20 74.1 6.1 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF3602) Mito_carr PF00153.27 ORY15053.1 - 9.8e-47 156.8 6.7 1.5e-16 60.1 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF1295 PF06966.12 ORY15054.1 - 7.1e-55 186.1 0.4 9.2e-55 185.7 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.14 ORY15054.1 - 1.9e-05 25.0 0.1 1.9e-05 25.0 0.1 2.0 3 0 0 3 3 3 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Steroid_dh PF02544.16 ORY15054.1 - 3.9e-05 23.7 0.1 3.9e-05 23.7 0.1 2.9 2 1 1 4 4 4 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.13 ORY15054.1 - 0.075 13.4 0.3 0.075 13.4 0.3 2.6 2 1 1 3 3 3 0 Phospholipid methyltransferase RNase_P_p30 PF01876.16 ORY15056.1 - 2.1e-58 197.3 0.0 2.6e-58 197.0 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit p30 Pkinase PF00069.25 ORY15057.1 - 2.6e-66 223.7 0.1 3e-66 223.5 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY15057.1 - 9.2e-20 71.0 0.0 1.3e-19 70.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 ORY15057.1 - 1.3e-07 31.8 0.0 2.3e-05 24.5 0.1 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 ORY15057.1 - 0.0044 15.9 0.0 0.0077 15.0 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 ORY15057.1 - 0.0044 16.4 0.0 0.0056 16.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 ORY15057.1 - 0.013 14.9 0.0 0.021 14.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 ORY15057.1 - 0.032 13.8 0.1 0.032 13.8 0.1 2.0 3 0 0 3 3 3 0 Choline/ethanolamine kinase tRNA-synt_1 PF00133.22 ORY15058.1 - 1.3e-218 727.2 0.1 2.8e-217 722.7 0.1 2.2 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 ORY15058.1 - 1.2e-31 109.7 0.8 1.2e-31 109.7 0.8 2.5 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 ORY15058.1 - 1.4e-12 47.1 1.2 0.00011 21.1 0.0 4.3 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 ORY15058.1 - 3.4e-12 46.3 0.2 4.2e-08 32.9 0.1 2.9 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 ORY15058.1 - 0.0097 15.3 0.0 0.23 10.8 0.0 2.6 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain CCDC53 PF10152.9 ORY15058.1 - 3.3 8.1 8.4 9.6 6.6 8.4 1.8 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Peptidase_C2 PF00648.21 ORY15059.1 - 3.8e-07 29.4 0.0 2.1e-06 27.0 0.0 2.0 1 1 0 1 1 1 1 Calpain family cysteine protease EthD PF07110.11 ORY15060.1 - 0.0014 19.7 0.1 0.0049 18.0 0.1 1.8 1 1 0 1 1 1 1 EthD domain DUF2117 PF09890.9 ORY15060.1 - 0.1 12.0 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2117) AMP-binding PF00501.28 ORY15061.1 - 1.2e-74 251.4 0.0 1.5e-74 251.1 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORY15061.1 - 7.8e-10 39.6 0.2 1.5e-07 32.3 0.2 2.5 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain HalOD2 PF18547.1 ORY15061.1 - 0.67 9.9 2.9 2.1 8.3 2.9 1.8 1 0 0 1 1 1 0 Halobacterial output domain 2 NUC202 PF08166.12 ORY15063.1 - 0.03 14.4 0.3 0.078 13.1 0.1 1.8 2 0 0 2 2 2 0 NUC202 domain APH PF01636.23 ORY15066.1 - 1e-37 130.4 0.0 1.5e-37 129.8 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 ORY15066.1 - 0.0024 17.5 0.0 0.33 10.5 0.0 2.2 2 0 0 2 2 2 2 RIO1 family EcKinase PF02958.20 ORY15066.1 - 0.02 14.2 0.0 0.036 13.4 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase RMMBL PF07521.12 ORY15066.1 - 0.048 13.6 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 Zn-dependent metallo-hydrolase RNA specificity domain Dynamin_N PF00350.23 ORY15069.1 - 3.7e-27 95.4 0.0 8.5e-27 94.3 0.0 1.6 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 ORY15069.1 - 5.4e-27 94.7 0.1 1.5e-25 90.0 0.1 2.4 1 1 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.23 ORY15069.1 - 5.6e-06 26.4 0.2 9.9e-05 22.4 0.0 2.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_15 PF13175.6 ORY15069.1 - 0.004 16.9 0.0 0.036 13.8 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain AbiJ_NTD4 PF18863.1 ORY15069.1 - 0.013 16.0 0.6 0.044 14.3 0.0 2.2 2 1 1 3 3 3 0 AbiJ N-terminal domain 4 AAA_29 PF13555.6 ORY15069.1 - 0.02 14.6 0.0 0.16 11.8 0.0 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF5082 PF16888.5 ORY15069.1 - 0.034 14.4 0.0 0.15 12.3 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) Roc PF08477.13 ORY15069.1 - 0.049 13.9 0.1 0.39 11.0 0.0 2.4 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase GED PF02212.18 ORY15069.1 - 0.12 12.5 3.7 0.45 10.7 0.1 3.0 3 0 0 3 3 3 0 Dynamin GTPase effector domain AAA_16 PF13191.6 ORY15069.1 - 0.19 12.1 4.3 0.31 11.4 0.1 3.1 2 2 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.6 ORY15069.1 - 5 7.6 7.7 6.3 7.2 0.0 3.3 3 1 0 3 3 3 0 AAA domain Reprolysin_5 PF13688.6 ORY15071.1 - 3e-06 27.5 0.0 4e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M43 PF05572.13 ORY15071.1 - 5.4e-06 26.4 0.0 8e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_4 PF13583.6 ORY15071.1 - 0.00011 21.9 0.0 0.00016 21.4 0.0 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M57 PF12388.8 ORY15071.1 - 0.00013 21.6 0.0 0.0002 21.1 0.0 1.2 1 0 0 1 1 1 1 Dual-action HEIGH metallo-peptidase Reprolysin_2 PF13574.6 ORY15071.1 - 0.00014 21.8 0.0 0.0002 21.3 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 ORY15071.1 - 0.0021 17.9 0.3 0.006 16.4 0.3 1.7 1 1 0 1 1 1 1 Matrixin DUF4953 PF16313.5 ORY15071.1 - 0.0041 16.4 0.0 0.0051 16.1 0.0 1.2 1 0 0 1 1 1 1 Met-zincin Peptidase_M66 PF10462.9 ORY15071.1 - 0.0063 15.5 0.0 0.0096 14.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase M66 Reprolysin_3 PF13582.6 ORY15071.1 - 0.012 16.2 0.0 0.016 15.7 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Astacin PF01400.24 ORY15071.1 - 0.2 11.3 0.0 0.37 10.4 0.0 1.4 1 0 0 1 1 1 0 Astacin (Peptidase family M12A) Pertussis_S2S3 PF02918.15 ORY15072.1 - 0.098 12.6 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Pertussis toxin, subunit 2 and 3, C-terminal domain Peptidase_M28 PF04389.17 ORY15073.1 - 3.5e-15 56.2 0.0 5.4e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 ORY15073.1 - 1.5e-05 24.9 0.1 6.1e-05 23.0 0.1 2.0 2 0 0 2 2 2 1 PA domain Ank_2 PF12796.7 ORY15076.1 - 1.8e-12 47.7 0.0 4.4e-10 40.0 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY15076.1 - 2e-09 37.8 0.1 0.0008 19.9 0.0 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY15076.1 - 5.1e-09 35.7 0.1 0.05 14.2 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 ORY15076.1 - 9.8e-09 35.3 0.1 0.0063 16.8 0.0 3.1 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 ORY15076.1 - 2.4e-05 24.5 1.3 1.4 9.5 0.1 3.9 4 0 0 4 4 4 3 Ankyrin repeat PT PF04886.12 ORY15078.1 - 0.065 12.8 4.5 2.6 7.6 0.2 3.6 2 2 1 3 3 3 0 PT repeat DUF3909 PF13077.6 ORY15078.1 - 0.13 12.4 0.5 3 8.0 0.5 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3909) DHDPS PF00701.22 ORY15079.1 - 6e-37 126.9 0.0 7.7e-37 126.6 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Toxin_ToxA PF11584.8 ORY15079.1 - 0.032 14.2 0.0 0.066 13.2 0.0 1.5 1 0 0 1 1 1 0 Proteinaceous host-selective toxin ToxA CPSF_A PF03178.15 ORY15081.1 - 2.6e-92 309.6 0.0 2.9e-92 309.4 0.0 1.0 1 0 0 1 1 1 1 CPSF A subunit region CBM_21 PF03370.13 ORY15103.1 - 3.3e-35 120.7 2.4 4.8e-35 120.1 2.4 1.2 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 ORY15103.1 - 3.8e-09 37.0 2.9 7.1e-09 36.1 2.9 1.4 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) AZUL PF16558.5 ORY15104.1 - 0.9 9.8 3.9 0.25 11.6 0.7 1.7 2 0 0 2 2 2 0 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A BolA PF01722.18 ORY15105.1 - 2e-10 40.8 0.0 6.1e-10 39.2 0.0 1.8 1 1 0 1 1 1 1 BolA-like protein HEAT PF02985.22 ORY15107.1 - 8.4e-05 22.5 4.5 0.63 10.5 0.0 5.9 6 0 0 6 6 6 2 HEAT repeat RTP1_C1 PF10363.9 ORY15107.1 - 0.00098 19.3 1.7 0.0085 16.3 0.0 3.4 4 0 0 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 Vps35 PF03635.17 ORY15107.1 - 0.037 12.5 0.3 0.054 12.0 0.3 1.3 1 0 0 1 1 1 0 Vacuolar protein sorting-associated protein 35 Tti2 PF10521.9 ORY15107.1 - 0.098 12.2 3.1 0.14 11.7 0.8 2.4 2 0 0 2 2 2 0 Tti2 family SPO22 PF08631.10 ORY15107.1 - 0.18 11.2 2.2 1 8.8 0.0 3.1 3 1 0 3 3 3 0 Meiosis protein SPO22/ZIP4 like HEAT PF02985.22 ORY15108.1 - 6.7e-06 25.9 0.0 0.074 13.3 0.1 4.8 5 0 0 5 5 5 2 HEAT repeat Cnd1 PF12717.7 ORY15108.1 - 0.00017 21.7 0.0 0.4 10.7 0.0 5.1 4 2 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 ORY15108.1 - 0.00048 20.6 1.2 0.046 14.2 0.0 4.4 5 0 0 5 5 5 1 HEAT-like repeat HEAT_2 PF13646.6 ORY15108.1 - 0.0024 18.2 0.1 0.72 10.3 0.0 4.5 5 0 0 5 5 5 1 HEAT repeats Nipped-B_C PF12830.7 ORY15108.1 - 0.0033 17.4 0.1 1.1 9.1 0.0 2.7 2 0 0 2 2 2 2 Sister chromatid cohesion C-terminus FANCI_S3 PF14677.6 ORY15108.1 - 0.017 14.8 0.0 5.5 6.6 0.0 3.1 3 0 0 3 3 3 0 FANCI solenoid 3 Adaptin_N PF01602.20 ORY15108.1 - 0.12 10.9 0.0 1.3 7.5 0.0 2.5 3 0 0 3 3 3 0 Adaptin N terminal region AA_permease_2 PF13520.6 ORY15110.1 - 1.8e-59 201.7 47.7 2.4e-59 201.3 47.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ORY15110.1 - 1.6e-26 93.0 37.2 2.2e-26 92.5 37.2 1.1 1 0 0 1 1 1 1 Amino acid permease DUF3043 PF11241.8 ORY15110.1 - 8.6 6.4 9.7 1.5 8.8 1.6 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3043) DAO PF01266.24 ORY15113.1 - 3.5e-29 102.5 0.0 5.1e-29 102.0 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 ORY15113.1 - 0.0028 18.1 0.0 0.0061 17.0 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Pyr_redox_2 PF07992.14 ORY15113.1 - 0.0034 16.6 0.0 0.0091 15.3 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ORY15113.1 - 0.0064 15.6 0.0 0.01 15.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain 3HCDH_N PF02737.18 ORY15113.1 - 0.043 13.7 0.0 0.064 13.1 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 ORY15113.1 - 0.045 13.0 0.0 0.069 12.4 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 ORY15113.1 - 0.049 14.2 1.0 0.049 14.2 1.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 ORY15113.1 - 0.1 12.2 0.1 0.17 11.5 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.14 ORY15113.1 - 0.11 12.0 0.5 0.2 11.2 0.5 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain GIDA PF01134.22 ORY15113.1 - 0.29 10.2 1.0 0.58 9.2 0.3 1.7 1 1 1 2 2 2 0 Glucose inhibited division protein A Sec61_beta PF03911.16 ORY15114.1 - 4.3e-17 61.9 1.5 6.5e-17 61.3 1.5 1.3 1 0 0 1 1 1 1 Sec61beta family DUF2981 PF11200.8 ORY15118.1 - 0.1 12.3 2.3 0.13 11.9 2.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) Tetraspanin PF00335.20 ORY15118.1 - 5.8 6.5 8.4 0.69 9.6 3.6 1.7 2 0 0 2 2 2 0 Tetraspanin family Aldo_ket_red PF00248.21 ORY15119.1 - 5.3e-43 147.3 0.0 7.9e-43 146.7 0.0 1.2 1 1 0 1 1 1 1 Aldo/keto reductase family MinC_N PF05209.13 ORY15119.1 - 0.14 12.1 0.1 23 5.0 0.0 2.7 2 1 1 3 3 3 0 Septum formation inhibitor MinC, N-terminal domain DUF35_N PF12172.8 ORY15120.1 - 0.061 13.2 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) ADH_N_2 PF16884.5 ORY15121.1 - 2.6e-22 78.8 0.0 4.3e-22 78.0 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 ORY15121.1 - 2e-21 76.3 0.3 3.8e-21 75.4 0.3 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ORY15121.1 - 7e-08 33.6 0.0 1.4e-07 32.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DapB_N PF01113.20 ORY15121.1 - 2.5 8.2 6.4 5 7.3 1.2 2.9 3 1 0 3 3 3 0 Dihydrodipicolinate reductase, N-terminus Zn_clus PF00172.18 ORY15122.1 - 1.8e-08 34.4 8.1 3e-08 33.7 8.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 ORY15122.1 - 2.2e-07 30.0 0.2 3.1e-07 29.6 0.2 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain ICMT PF04140.14 ORY15123.1 - 1.1e-27 96.2 0.1 2.4e-27 95.2 0.1 1.5 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 ORY15123.1 - 1.1e-10 41.9 1.4 1.1e-10 41.9 1.4 1.9 2 0 0 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.12 ORY15123.1 - 4e-08 33.1 0.6 5.6e-08 32.6 0.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) NnrU PF07298.11 ORY15123.1 - 7.5e-05 22.3 0.2 0.00015 21.4 0.2 1.5 1 0 0 1 1 1 1 NnrU protein zf-RING_2 PF13639.6 ORY15125.1 - 6.5e-08 32.8 6.4 5.4e-07 29.8 3.4 2.2 2 0 0 2 2 2 1 Ring finger domain Prok-RING_4 PF14447.6 ORY15125.1 - 1.2e-06 28.2 5.3 4e-06 26.6 2.2 2.2 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 ORY15125.1 - 4.3e-06 26.6 4.6 0.0014 18.6 2.8 2.7 2 1 0 2 2 2 2 RING-type zinc-finger zf-C3HC4_2 PF13923.6 ORY15125.1 - 5.4e-06 26.2 2.7 5.4e-06 26.2 2.7 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORY15125.1 - 8.9e-06 25.6 6.1 9.8e-05 22.2 6.1 2.1 1 1 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 ORY15125.1 - 1.3e-05 25.3 0.4 1.3e-05 25.3 0.4 2.0 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 ORY15125.1 - 0.00014 21.7 5.2 0.00071 19.4 2.4 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Rad50_zn_hook PF04423.14 ORY15125.1 - 0.00032 20.5 0.7 0.1 12.5 0.1 2.3 2 0 0 2 2 2 1 Rad50 zinc hook motif zf-Nse PF11789.8 ORY15125.1 - 0.00054 19.7 3.2 0.063 13.1 0.7 2.2 2 0 0 2 2 2 2 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.6 ORY15125.1 - 0.0033 17.5 5.1 0.017 15.3 2.8 2.6 2 1 1 3 3 3 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 ORY15125.1 - 0.0058 16.5 2.5 0.0058 16.5 2.5 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C2HC_2 PF13913.6 ORY15125.1 - 0.0081 16.0 0.4 0.0081 16.0 0.4 2.5 2 0 0 2 2 2 1 zinc-finger of a C2HC-type UPF0547 PF10571.9 ORY15125.1 - 0.0087 16.1 2.7 5.8 7.1 0.0 3.3 3 0 0 3 3 3 1 Uncharacterised protein family UPF0547 zf-RING_4 PF14570.6 ORY15125.1 - 0.0095 15.7 4.9 0.47 10.3 1.9 3.0 2 1 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 ORY15125.1 - 0.041 13.9 1.5 0.05 13.7 0.2 1.7 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-P11 PF03854.14 ORY15125.1 - 0.043 13.5 4.6 0.54 10.0 1.2 2.2 2 0 0 2 2 2 0 P-11 zinc finger Rtf2 PF04641.12 ORY15125.1 - 0.065 12.6 0.8 0.072 12.4 0.1 1.4 2 0 0 2 2 2 0 Rtf2 RING-finger DZR PF12773.7 ORY15125.1 - 0.44 10.6 5.1 4.4 7.4 5.1 2.2 1 1 0 1 1 1 0 Double zinc ribbon Zn-ribbon_8 PF09723.10 ORY15125.1 - 0.68 10.1 4.8 10 6.3 1.3 2.4 2 0 0 2 2 2 0 Zinc ribbon domain Zn-C2H2_12 PF18112.1 ORY15125.1 - 1.4 9.4 0.1 1.4 9.4 0.1 2.5 3 0 0 3 3 2 0 Autophagy receptor zinc finger-C2H2 domain zf-C2H2_4 PF13894.6 ORY15125.1 - 2.2 9.3 6.1 4.3 8.4 0.1 2.9 3 0 0 3 3 3 0 C2H2-type zinc finger zinc_ribbon_5 PF13719.6 ORY15125.1 - 2.3 8.0 5.8 22 4.9 0.2 3.0 3 0 0 3 3 3 0 zinc-ribbon domain zf-C2H2 PF00096.26 ORY15125.1 - 3.5 8.2 6.0 6.4 7.4 0.1 3.1 3 0 0 3 3 3 0 Zinc finger, C2H2 type FYVE PF01363.21 ORY15125.1 - 4.8 7.4 7.8 5.8 7.1 0.2 2.9 1 1 1 2 2 2 0 FYVE zinc finger Methyltransf_25 PF13649.6 ORY15127.1 - 1.9e-15 57.3 0.0 6e-15 55.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY15127.1 - 4.8e-14 52.4 0.0 6.2e-14 52.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY15127.1 - 6.1e-13 49.2 0.0 2e-12 47.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY15127.1 - 1.8e-11 44.6 0.0 4.3e-11 43.4 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY15127.1 - 1.5e-07 31.4 0.0 2.7e-07 30.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ORY15127.1 - 1.2e-05 24.9 0.0 2.1e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 ORY15127.1 - 3.3e-05 23.4 0.0 5.8e-05 22.5 0.0 1.4 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family tRNA_U5-meth_tr PF05958.11 ORY15127.1 - 0.00022 20.3 0.0 0.00031 19.8 0.0 1.1 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_2 PF00891.18 ORY15127.1 - 0.03 13.6 0.0 0.041 13.2 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_4 PF02390.17 ORY15127.1 - 0.1 12.1 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase zf-NOSIP PF15906.5 ORY15129.1 - 4.2e-08 33.2 0.0 1.4e-07 31.5 0.0 1.9 2 0 0 2 2 2 1 Zinc-finger of nitric oxide synthase-interacting protein zf-C3HC4_3 PF13920.6 ORY15129.1 - 4.4e-06 26.5 21.2 0.0014 18.4 10.1 3.6 2 1 1 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORY15129.1 - 0.00012 22.0 7.6 0.00012 22.0 7.6 3.1 2 1 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 ORY15129.1 - 0.00012 22.0 2.9 0.00012 22.0 2.9 3.1 3 0 0 3 3 3 2 RING-type zinc-finger zf-RING_2 PF13639.6 ORY15129.1 - 0.0013 19.0 21.8 0.0034 17.7 7.7 3.1 3 1 1 4 4 4 2 Ring finger domain zf-C3HC4 PF00097.25 ORY15129.1 - 0.0027 17.6 5.0 0.0027 17.6 5.0 3.0 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 ORY15129.1 - 0.0033 17.2 21.1 0.0036 17.1 4.6 3.1 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.21 ORY15129.1 - 0.0054 16.8 11.9 0.067 13.3 7.0 3.4 2 1 0 2 2 2 1 FYVE zinc finger Vps39_2 PF10367.9 ORY15129.1 - 0.039 14.4 1.3 0.039 14.4 1.3 2.1 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 Prok-RING_4 PF14447.6 ORY15129.1 - 0.052 13.4 20.7 0.58 10.1 8.6 3.6 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 ORY15129.1 - 0.22 11.7 17.2 0.07 13.3 4.7 2.9 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zinc-ribbons_6 PF07191.12 ORY15129.1 - 1 9.4 13.6 7.8 6.6 2.1 3.4 2 1 1 3 3 3 0 zinc-ribbons Rtf2 PF04641.12 ORY15129.1 - 3.7 6.8 24.8 3.5 6.9 14.1 3.4 2 2 1 3 3 3 0 Rtf2 RING-finger Acyltransferase PF01553.21 ORY15130.1 - 2.9e-15 56.1 0.0 7.3e-15 54.8 0.0 1.6 1 1 0 1 1 1 1 Acyltransferase CBFD_NFYB_HMF PF00808.23 ORY15131.1 - 6.3e-15 55.2 1.6 6.3e-15 55.2 1.6 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 ORY15131.1 - 0.00038 20.8 2.9 0.00052 20.4 0.1 2.1 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Lipase_GDSL_2 PF13472.6 ORY15132.1 - 7e-21 75.4 0.3 1e-20 74.8 0.3 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 ORY15132.1 - 2.6e-07 30.8 0.0 6.1e-07 29.6 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase ADH_zinc_N PF00107.26 ORY15133.1 - 1.6e-10 41.1 0.2 2.9e-10 40.2 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ORY15133.1 - 6.4e-10 38.9 0.0 1.3e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 ORY15133.1 - 0.025 15.6 0.0 0.046 14.8 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Eno-Rase_NADH_b PF12242.8 ORY15133.1 - 0.11 12.2 0.1 0.24 11.2 0.1 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Peptidase_M43 PF05572.13 ORY15134.1 - 9.7e-18 64.5 0.4 1.4e-17 64.0 0.4 1.2 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_4 PF13583.6 ORY15134.1 - 0.0011 18.7 0.8 0.0022 17.7 0.6 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 ORY15134.1 - 0.0011 19.2 2.3 0.0019 18.4 2.2 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 ORY15134.1 - 0.0013 18.7 1.4 0.0025 17.7 1.4 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 ORY15134.1 - 0.0083 16.6 0.2 0.019 15.5 0.0 1.9 2 1 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Lustrin_cystein PF14625.6 ORY15134.1 - 0.034 14.5 0.7 0.099 13.0 0.7 1.8 1 0 0 1 1 1 0 Lustrin, cysteine-rich repeated domain Solute_trans_a PF03619.16 ORY15136.1 - 1.1e-90 303.7 19.1 1.3e-90 303.5 19.1 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Jagunal PF07086.12 ORY15136.1 - 0.36 10.9 7.2 4.7 7.3 1.5 2.6 2 0 0 2 2 2 0 Jagunal, ER re-organisation during oogenesis DPM3 PF08285.11 ORY15136.1 - 3.1 8.1 6.3 0.96 9.7 1.8 2.4 2 0 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) SAP PF02037.27 ORY15137.1 - 1.1e-07 31.4 0.1 1.8e-07 30.7 0.1 1.3 1 0 0 1 1 1 1 SAP domain RSB_motif PF16294.5 ORY15137.1 - 1.5e-05 25.2 0.5 1.5e-05 25.2 0.5 2.8 2 0 0 2 2 2 1 RNSP1-SAP18 binding (RSB) motif VASt PF16016.5 ORY15138.1 - 6e-34 117.7 0.0 1e-33 116.9 0.0 1.4 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 ORY15138.1 - 6.3e-22 77.6 0.1 3.2e-21 75.3 0.0 2.0 2 0 0 2 2 2 1 GRAM domain TolA_bind_tri PF16331.5 ORY15139.1 - 0.25 11.4 9.1 2.8 8.1 0.5 3.3 3 0 0 3 3 3 0 TolA binding protein trimerisation CENP-Q PF13094.6 ORY15139.1 - 0.41 10.8 12.0 0.076 13.2 5.9 2.7 3 0 0 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit YabA PF06156.13 ORY15139.1 - 0.7 10.6 5.4 1.5 9.5 0.0 2.5 2 0 0 2 2 2 0 Initiation control protein YabA Lebercilin PF15619.6 ORY15139.1 - 1 9.0 11.1 0.17 11.5 0.6 2.6 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease BRE1 PF08647.11 ORY15139.1 - 1.3 9.2 10.1 5.8 7.1 0.5 2.6 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase CPSase_sm_chain PF00988.22 ORY15140.1 - 1.1e-46 157.8 0.0 3.9e-46 156.0 0.0 1.8 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 ORY15140.1 - 7.2e-46 156.4 0.0 1e-45 155.9 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 ORY15140.1 - 0.00016 21.5 0.4 0.002 17.9 0.4 2.5 2 1 0 2 2 2 1 Peptidase C26 DJ-1_PfpI PF01965.24 ORY15140.1 - 0.0027 17.6 0.0 0.025 14.4 0.0 2.1 2 0 0 2 2 2 1 DJ-1/PfpI family mRNA_cap_enzyme PF01331.19 ORY15141.1 - 9e-50 169.2 0.0 1.5e-49 168.5 0.0 1.3 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 ORY15141.1 - 6.9e-29 100.7 0.0 1.1e-28 100.0 0.0 1.3 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.21 ORY15141.1 - 4.2e-05 23.3 0.0 0.00077 19.2 0.0 2.5 1 1 1 2 2 2 1 ATP dependent DNA ligase domain RNA_ligase PF09414.10 ORY15141.1 - 0.0014 18.9 0.0 0.0027 18.0 0.0 1.5 1 0 0 1 1 1 1 RNA ligase DNA_pol_B_thumb PF14791.6 ORY15142.1 - 3.9e-21 75.0 0.0 8.3e-21 73.9 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_B_palm PF14792.6 ORY15142.1 - 1.3e-19 70.4 0.2 3e-19 69.3 0.2 1.6 1 1 0 1 1 1 1 DNA polymerase beta palm DNA_pol_lambd_f PF10391.9 ORY15142.1 - 7.8e-18 64.0 1.0 2.3e-17 62.5 1.0 1.9 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.6 ORY15142.1 - 1.9e-08 34.5 0.0 7.3e-08 32.7 0.0 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH_5 PF14520.6 ORY15142.1 - 0.059 14.0 0.0 13 6.5 0.0 3.0 3 0 0 3 3 3 0 Helix-hairpin-helix domain IMS_C PF11799.8 ORY15142.1 - 0.13 12.9 0.0 0.44 11.3 0.0 2.0 1 1 0 1 1 1 0 impB/mucB/samB family C-terminal domain BRCT_2 PF16589.5 ORY15142.1 - 0.19 12.2 0.0 0.37 11.2 0.0 1.5 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain Autophagy_N PF03986.13 ORY15144.1 - 8.1e-43 145.7 0.3 1.4e-42 144.9 0.0 1.5 2 0 0 2 2 2 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_C PF10381.9 ORY15144.1 - 5.9e-16 57.7 0.6 9.9e-16 56.9 0.6 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal Autophagy_act_C PF03987.15 ORY15144.1 - 6.4e-15 55.5 0.1 1.1e-14 54.7 0.1 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain DIOX_N PF14226.6 ORY15145.1 - 3.6e-25 89.0 0.0 5.7e-25 88.4 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 ORY15145.1 - 1.1e-13 51.5 0.0 2.6e-13 50.3 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PHF5 PF03660.14 ORY15146.1 - 2.4e-51 172.3 10.8 2.7e-51 172.1 10.8 1.0 1 0 0 1 1 1 1 PHF5-like protein PolC_DP2 PF03833.13 ORY15146.1 - 0.92 7.3 7.3 0.055 11.3 2.5 1.2 1 1 0 1 1 1 0 DNA polymerase II large subunit DP2 DZR PF12773.7 ORY15146.1 - 5.3 7.2 16.4 7.4 6.7 2.4 3.0 1 1 1 2 2 2 0 Double zinc ribbon Pinin_SDK_memA PF04696.13 ORY15147.1 - 5.6e-26 91.1 10.6 5.6e-26 91.1 10.6 2.9 3 0 0 3 3 3 1 pinin/SDK/memA/ protein conserved region RSB_motif PF16294.5 ORY15147.1 - 0.0015 18.8 5.4 0.0015 18.8 5.4 4.2 2 1 2 4 4 4 1 RNSP1-SAP18 binding (RSB) motif Abhydrolase_1 PF00561.20 ORY15149.1 - 4.5e-27 95.3 0.2 1.4e-20 74.0 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORY15149.1 - 2.4e-14 54.5 0.4 3e-14 54.1 0.4 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORY15149.1 - 6.8e-12 45.2 0.0 1.4e-09 37.5 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 ORY15149.1 - 0.021 14.6 0.0 1.3 8.8 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase family ADH_N PF08240.12 ORY15151.1 - 4.6e-28 97.3 0.7 3.3e-27 94.5 0.2 2.2 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORY15151.1 - 1.3e-17 64.0 0.3 2.7e-17 63.0 0.3 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 ORY15151.1 - 1.4e-06 28.0 1.1 0.0031 17.0 0.3 2.8 1 1 2 3 3 3 2 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 ORY15151.1 - 0.019 14.2 1.2 0.036 13.4 1.2 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.6 ORY15151.1 - 0.024 15.7 0.0 0.054 14.6 0.0 1.7 1 0 0 1 1 1 0 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.14 ORY15151.1 - 0.029 14.0 0.2 0.062 12.9 0.2 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain XdhC_C PF13478.6 ORY15151.1 - 0.041 14.4 0.2 0.077 13.5 0.2 1.4 1 0 0 1 1 1 0 XdhC Rossmann domain 3HCDH_N PF02737.18 ORY15151.1 - 0.16 11.8 0.9 0.25 11.2 0.9 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MitMem_reg PF13012.6 ORY15152.1 - 2.3e-12 47.3 0.0 5.9e-12 46.0 0.0 1.6 1 1 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 ORY15152.1 - 4.2e-10 39.6 0.0 1e-09 38.4 0.0 1.6 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Viral_NABP PF05515.11 ORY15153.1 - 1.2 8.9 5.4 1.5 8.6 0.1 2.1 1 1 1 2 2 2 0 Viral nucleic acid binding UCH PF00443.29 ORY15157.1 - 3.1e-36 125.2 0.1 6.7e-36 124.1 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF3517 PF12030.8 ORY15157.1 - 3.9e-29 101.6 0.1 9.1e-29 100.4 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3517) UCH_1 PF13423.6 ORY15157.1 - 4.2e-22 79.1 0.1 8.9e-22 78.1 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_P_pop3 PF08228.11 ORY15158.1 - 0.00013 22.0 0.0 0.061 13.4 0.0 2.5 3 0 0 3 3 3 2 RNase P subunit Pop3 SRP_TPR_like PF17004.5 ORY15159.1 - 1.4e-21 76.7 2.8 1.4e-21 76.7 2.8 2.3 2 0 0 2 2 2 1 Putative TPR-like repeat SRP72 PF08492.12 ORY15159.1 - 8.2e-13 48.6 7.2 8.2e-13 48.6 7.2 2.6 2 0 0 2 2 2 1 SRP72 RNA-binding domain TPR_1 PF00515.28 ORY15159.1 - 8.1e-07 28.6 4.9 0.01 15.6 0.1 5.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 ORY15159.1 - 1e-06 29.1 20.8 0.033 14.7 2.4 6.3 4 2 1 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 ORY15159.1 - 1.9e-05 24.4 24.3 0.0031 17.5 0.8 7.3 7 1 1 8 8 7 2 Tetratricopeptide repeat TPR_10 PF13374.6 ORY15159.1 - 2e-05 24.3 6.8 2.3 8.2 0.1 5.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 ORY15159.1 - 7.1e-05 23.4 13.8 0.0045 17.6 2.5 5.1 4 1 0 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY15159.1 - 0.00014 22.0 18.6 0.027 14.7 0.6 5.6 5 1 1 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 ORY15159.1 - 0.0028 17.9 16.1 0.059 13.7 0.5 5.5 5 1 0 6 6 5 1 Tetratricopeptide repeat GGA_N-GAT PF18308.1 ORY15159.1 - 0.0062 16.1 0.7 0.15 11.7 0.0 2.7 2 0 0 2 2 2 1 GGA N-GAT domain TPR_8 PF13181.6 ORY15159.1 - 0.008 16.3 9.6 0.16 12.3 0.2 5.4 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 ORY15159.1 - 0.016 16.0 21.5 3.5 8.7 2.1 7.9 7 1 2 9 9 8 0 Tetratricopeptide repeat AcylCoA_dehyd_C PF12186.8 ORY15159.1 - 0.024 14.7 0.2 3.2 7.9 0.0 2.9 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase C terminal TPR_7 PF13176.6 ORY15159.1 - 0.042 13.9 11.3 0.44 10.7 0.1 4.9 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_17 PF13431.6 ORY15159.1 - 0.055 13.9 5.6 0.86 10.1 0.1 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_20 PF14561.6 ORY15159.1 - 0.12 12.7 12.9 0.72 10.2 1.2 4.4 3 1 1 4 4 4 0 Tetratricopeptide repeat PPR PF01535.20 ORY15159.1 - 0.14 12.4 0.0 30 5.1 0.0 3.5 3 0 0 3 3 3 0 PPR repeat TPR_4 PF07721.14 ORY15159.1 - 0.24 12.2 7.4 2.4e+02 2.8 0.0 5.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_9 PF13371.6 ORY15159.1 - 0.51 10.5 5.6 2.1 8.6 0.1 3.4 3 1 1 4 4 3 0 Tetratricopeptide repeat TFIIE_alpha PF02002.17 ORY15160.1 - 6.2e-10 38.9 0.3 1.2e-09 38.0 0.3 1.4 1 0 0 1 1 1 1 TFIIE alpha subunit zf-Di19 PF05605.12 ORY15160.1 - 0.026 14.8 0.9 0.054 13.8 0.9 1.4 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding PhnA_Zn_Ribbon PF08274.12 ORY15160.1 - 0.033 14.1 0.5 0.16 11.9 0.0 2.1 2 0 0 2 2 2 0 PhnA Zinc-Ribbon Endonuclease_7 PF02945.15 ORY15160.1 - 0.1 12.5 0.1 0.2 11.6 0.1 1.4 1 0 0 1 1 1 0 Recombination endonuclease VII PHD PF00628.29 ORY15160.1 - 0.17 11.8 0.6 3.3 7.7 0.2 2.3 2 0 0 2 2 2 0 PHD-finger DnaG_DnaB_bind PF08278.11 ORY15160.1 - 2 9.1 6.3 5.4 7.6 5.1 2.4 2 1 0 2 2 2 0 DNA primase DnaG DnaB-binding PseudoU_synth_1 PF01416.20 ORY15161.1 - 5.7e-09 36.4 0.0 1.4e-07 32.0 0.0 2.6 2 0 0 2 2 2 1 tRNA pseudouridine synthase COesterase PF00135.28 ORY15162.1 - 2.7e-90 303.7 0.0 3.4e-90 303.4 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 ORY15162.1 - 4.7e-06 26.6 0.2 6.2e-05 23.0 0.2 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 ORY15162.1 - 0.0002 20.9 0.2 0.00033 20.2 0.2 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Glyco_hydro_80 PF13647.6 ORY15162.1 - 0.093 12.2 0.1 0.15 11.5 0.1 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 80 of chitosanase A Mito_carr PF00153.27 ORY15163.1 - 1.1e-47 159.8 6.3 7e-17 61.1 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein WD40 PF00400.32 ORY15164.1 - 4.5e-40 134.9 21.8 1.3e-07 32.2 0.1 6.9 6 0 0 6 6 6 6 WD domain, G-beta repeat F-box-like PF12937.7 ORY15164.1 - 5.7e-10 38.9 0.4 1e-09 38.1 0.4 1.5 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 ORY15164.1 - 2.2e-09 37.5 0.9 0.023 15.0 0.0 5.8 1 1 5 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain F-box PF00646.33 ORY15164.1 - 6.8e-07 29.0 0.3 1.3e-06 28.1 0.3 1.5 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.8 ORY15164.1 - 9.4e-07 27.8 4.9 1.3 7.5 0.1 6.2 2 1 5 7 7 7 4 Nucleoporin Nup120/160 WD40_like PF17005.5 ORY15164.1 - 0.00059 19.3 0.0 0.067 12.5 0.0 2.9 1 1 3 4 4 4 2 WD40-like domain Glyco_hydro_61 PF03443.14 ORY15165.1 - 9.9e-51 172.6 0.3 1.2e-50 172.3 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Abhydrolase_1 PF00561.20 ORY15166.1 - 4.7e-43 147.7 0.0 1.1e-42 146.4 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 ORY15166.1 - 0.015 15.0 0.0 0.028 14.1 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Sugar_tr PF00083.24 ORY15167.1 - 1.3e-51 175.9 22.9 1.7e-51 175.6 22.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY15167.1 - 2.9e-20 72.5 36.6 2.9e-20 72.5 36.6 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 ORY15167.1 - 3.2e-05 22.7 8.2 3.2e-05 22.7 8.2 3.1 2 1 1 3 3 3 2 MFS/sugar transport protein MFS_1_like PF12832.7 ORY15167.1 - 0.042 12.7 21.4 0.51 9.1 4.3 2.6 2 1 1 3 3 3 0 MFS_1 like family Ku PF02735.16 ORY15168.1 - 4.1e-44 150.7 0.0 8.9e-44 149.6 0.0 1.5 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 ORY15168.1 - 4.4e-36 124.7 0.0 7.6e-36 123.9 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 ORY15168.1 - 5.3e-22 78.3 1.0 1.4e-21 76.9 1.0 1.8 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm SAP PF02037.27 ORY15168.1 - 4e-08 32.8 0.1 8.6e-08 31.8 0.1 1.6 1 0 0 1 1 1 1 SAP domain Ferrochelatase PF00762.19 ORY15169.1 - 4.2e-98 328.3 0.0 5.1e-98 328.1 0.0 1.1 1 0 0 1 1 1 1 Ferrochelatase E1_dh PF00676.20 ORY15170.1 - 5e-115 383.6 0.1 6e-115 383.3 0.1 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 ORY15170.1 - 0.00053 19.3 0.2 0.00085 18.6 0.2 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase MFS_1 PF07690.16 ORY15171.1 - 2.4e-32 112.2 31.2 9.6e-30 103.7 17.9 2.1 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY15171.1 - 3.6e-14 52.5 0.7 3.6e-14 52.5 0.7 2.6 3 0 0 3 3 3 1 Sugar (and other) transporter MFS_4 PF06779.14 ORY15171.1 - 0.00026 20.4 9.4 0.0027 17.1 2.1 2.3 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB DUF1751 PF08551.10 ORY15171.1 - 0.00045 20.7 0.1 0.0013 19.2 0.0 1.8 2 0 0 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) MFS_3 PF05977.13 ORY15171.1 - 0.077 11.4 8.1 0.032 12.6 4.4 2.1 2 1 0 2 2 2 0 Transmembrane secretion effector EST1_DNA_bind PF10373.9 ORY15172.1 - 2e-16 60.3 0.1 4.1e-16 59.3 0.1 1.5 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain MgtE PF01769.16 ORY15173.1 - 0.12 12.8 5.7 0.19 12.1 5.7 1.3 1 0 0 1 1 1 0 Divalent cation transporter Shisa PF13908.6 ORY15173.1 - 1.1 9.5 5.0 1.4 9.1 5.0 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF3270 PF11674.8 ORY15173.1 - 1.1 9.5 7.0 2.3 8.4 7.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3270) SP_C-Propep PF08999.10 ORY15173.1 - 3.3 7.5 9.6 7.1 6.5 9.6 1.6 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide Glycos_transf_2 PF00535.26 ORY15176.1 - 3.5e-22 79.0 0.0 3.1e-21 75.9 0.0 2.1 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 ORY15176.1 - 5.9e-09 36.2 0.1 0.004 17.1 0.0 2.3 1 1 1 2 2 2 2 Glycosyltransferase like family 2 DUF3445 PF11927.8 ORY15177.1 - 6.4e-77 258.2 0.0 8.6e-77 257.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) NmrA PF05368.13 ORY15179.1 - 5.7e-24 85.0 0.0 1.3e-23 83.8 0.0 1.4 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ORY15179.1 - 1.3e-05 25.2 0.0 1.9e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding PhoLip_ATPase_C PF16212.5 ORY15180.1 - 1.1e-82 277.6 22.9 1.1e-82 277.6 22.9 2.1 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 ORY15180.1 - 8.1e-28 95.9 6.8 2.1e-27 94.6 6.8 1.8 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 ORY15180.1 - 3.2e-11 43.2 0.0 3.2e-10 40.0 0.0 2.5 3 0 0 3 3 3 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 ORY15180.1 - 1.4e-10 41.8 2.1 2.6e-06 27.9 0.5 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 ORY15180.1 - 1.1e-05 25.0 0.0 3e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 ORY15180.1 - 0.0021 17.9 0.0 0.023 14.4 0.0 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Formyl_trans_N PF00551.19 ORY15184.1 - 1.7e-40 138.7 0.0 2e-40 138.5 0.0 1.0 1 0 0 1 1 1 1 Formyl transferase SnoaL_2 PF12680.7 ORY15184.1 - 0.11 13.2 0.1 0.19 12.4 0.1 1.5 1 0 0 1 1 1 0 SnoaL-like domain Hat1_N PF10394.9 ORY15185.1 - 8.4e-36 123.6 0.0 6.1e-35 120.8 0.0 2.3 2 1 0 2 2 2 1 Histone acetyl transferase HAT1 N-terminus Zip PF02535.22 ORY15186.1 - 2e-33 116.0 26.4 3.6e-25 88.9 12.1 3.7 2 1 1 3 3 3 3 ZIP Zinc transporter RRM_1 PF00076.22 ORY15188.1 - 3.1e-28 97.4 0.4 3.6e-15 55.5 0.0 3.6 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 ORY15188.1 - 0.001 18.7 0.0 1.3 8.7 0.0 3.2 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 ORY15188.1 - 0.0014 18.7 0.0 0.19 11.9 0.0 2.6 2 1 0 2 2 2 1 RNA recognition motif Limkain-b1 PF11608.8 ORY15188.1 - 0.12 12.4 0.0 22 5.2 0.0 2.8 3 0 0 3 3 3 0 Limkain b1 FXMRP1_C_core PF12235.8 ORY15188.1 - 7.1 7.3 18.2 70 4.1 18.6 2.3 1 1 1 2 2 2 0 Fragile X-related 1 protein core C terminal FAD_binding_1 PF00667.20 ORY15189.1 - 3.4e-38 131.4 0.0 5.4e-38 130.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 ORY15189.1 - 1.8e-30 106.0 0.0 4.6e-30 104.7 0.0 1.7 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.21 ORY15189.1 - 1.3e-15 58.0 0.0 2.8e-15 56.9 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_3 PF12641.7 ORY15189.1 - 0.011 15.4 0.0 0.23 11.1 0.0 2.2 2 0 0 2 2 2 0 Flavodoxin domain FAD_binding_6 PF00970.24 ORY15189.1 - 0.061 13.7 0.0 0.21 12.0 0.0 1.8 2 0 0 2 2 2 0 Oxidoreductase FAD-binding domain Flavodoxin_5 PF12724.7 ORY15189.1 - 0.07 13.4 0.0 9.4 6.5 0.0 2.7 2 1 1 3 3 3 0 Flavodoxin domain POPLD PF08170.12 ORY15189.1 - 0.08 13.3 0.0 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 POPLD (NUC188) domain ETF PF01012.21 ORY15190.1 - 6.7e-43 146.7 1.8 8e-43 146.4 1.8 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain bVLRF1 PF18826.1 ORY15191.1 - 1.4e-58 197.0 0.3 1.4e-58 197.0 0.3 2.1 2 0 0 2 2 2 1 bacteroidetes VLRF1 release factor Ank_5 PF13857.6 ORY15191.1 - 8.6e-06 25.9 0.1 2.8e-05 24.3 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 ORY15191.1 - 3e-05 24.3 0.7 0.0011 19.3 0.2 3.0 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 ORY15191.1 - 0.00092 19.5 0.2 0.0056 17.1 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.7 ORY15191.1 - 0.0022 18.5 0.0 0.0052 17.4 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) zf-C2H2_3rep PF18868.1 ORY15191.1 - 0.21 12.3 0.7 0.86 10.3 0.0 2.3 2 0 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats TPR_12 PF13424.6 ORY15193.1 - 7.8e-30 103.0 13.6 6.4e-09 36.0 0.1 7.0 5 1 2 7 7 7 5 Tetratricopeptide repeat TPR_10 PF13374.6 ORY15193.1 - 1.6e-28 97.7 7.7 1.4e-05 24.8 0.1 9.0 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_2 PF07719.17 ORY15193.1 - 2.7e-10 39.6 15.1 2.5 8.4 0.0 9.0 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_14 PF13428.6 ORY15193.1 - 2.5e-06 27.8 2.5 2.1 9.4 0.0 6.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 ORY15193.1 - 5.1e-06 26.2 0.5 3 8.1 0.0 5.6 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_MalT PF17874.1 ORY15193.1 - 1.7e-05 24.4 0.4 0.18 11.1 0.0 3.1 1 1 1 3 3 3 2 MalT-like TPR region TPR_1 PF00515.28 ORY15193.1 - 1.7e-05 24.4 11.6 0.18 11.7 0.2 7.1 10 0 0 10 10 9 1 Tetratricopeptide repeat TPR_8 PF13181.6 ORY15193.1 - 4.7e-05 23.3 7.4 3.7 8.0 0.0 6.8 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_19 PF14559.6 ORY15193.1 - 0.00026 21.4 6.1 8.4 7.0 0.0 5.9 5 2 2 7 7 7 1 Tetratricopeptide repeat TPR_16 PF13432.6 ORY15193.1 - 0.0015 19.1 2.1 48 4.7 0.0 5.6 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_4 PF07721.14 ORY15193.1 - 0.0085 16.6 5.1 5.1 8.0 0.2 4.7 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_5 PF12688.7 ORY15193.1 - 0.012 15.9 0.1 1.2 9.4 0.0 3.3 3 0 0 3 3 3 0 Tetratrico peptide repeat TPR_17 PF13431.6 ORY15193.1 - 0.22 12.0 6.0 87 3.9 0.0 5.8 7 1 0 7 7 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 ORY15193.1 - 0.75 10.6 2.5 3.2e+02 2.3 0.0 4.8 5 0 0 5 5 4 0 Tetratricopeptide repeat Isochorismatase PF00857.20 ORY15194.1 - 7.4e-25 88.1 0.0 9.8e-17 61.7 0.0 2.2 2 0 0 2 2 2 2 Isochorismatase family TPR_12 PF13424.6 ORY15195.1 - 0.0051 17.1 0.0 0.015 15.6 0.0 1.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 ORY15195.1 - 0.014 16.1 1.2 0.078 13.6 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 ORY15195.1 - 0.12 12.2 0.0 0.39 10.6 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF3087 PF11286.8 ORY15195.1 - 0.16 11.4 0.0 0.34 10.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3087) TPR_2 PF07719.17 ORY15195.1 - 0.99 9.7 0.0 0.99 9.7 0.0 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat U3_snoRNA_assoc PF08297.11 ORY15196.1 - 1e-19 71.0 1.7 1e-19 71.0 1.7 2.8 3 1 0 3 3 3 1 U3 snoRNA associated Neuregulin PF02158.15 ORY15196.1 - 0.13 11.6 5.9 0.089 12.1 3.2 1.8 1 1 1 2 2 2 0 Neuregulin intracellular region Ureide_permease PF07168.11 ORY15196.1 - 7.6 5.2 4.4 12 4.6 4.4 1.2 1 0 0 1 1 1 0 Ureide permease DEAD PF00270.29 ORY15199.1 - 1.1e-29 103.4 0.0 4.6e-29 101.4 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY15199.1 - 1e-19 70.9 0.0 6.5e-19 68.3 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY15199.1 - 0.0007 19.6 0.0 0.0056 16.7 0.0 2.3 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 ORY15199.1 - 0.04 14.2 0.0 14 5.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain PH PF00169.29 ORY15200.1 - 1.5e-08 35.1 0.2 7.2e-08 32.9 0.0 2.3 2 0 0 2 2 2 1 PH domain Anillin PF08174.11 ORY15200.1 - 2.9e-05 24.5 0.0 0.00012 22.5 0.0 2.1 2 0 0 2 2 2 1 Cell division protein anillin Nop53 PF07767.11 ORY15201.1 - 1.1 8.6 13.3 1.6 8.0 13.3 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) HAUS6_N PF14661.6 ORY15201.1 - 4.2 6.9 9.2 6.4 6.3 9.2 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus SET PF00856.28 ORY15202.1 - 6.8e-13 49.3 1.0 6e-09 36.5 0.0 3.6 3 1 0 3 3 3 2 SET domain FANCD2OS PF15124.6 ORY15202.1 - 0.0036 17.5 0.3 0.015 15.5 0.3 2.1 2 0 0 2 2 2 1 FANCD2 opposite strand protein SAF PF08666.12 ORY15202.1 - 0.015 15.9 0.3 5.3 7.8 0.0 3.2 3 0 0 3 3 3 0 SAF domain Bac_luciferase PF00296.20 ORY15202.1 - 0.16 11.4 0.1 0.66 9.3 0.0 1.8 1 1 0 2 2 2 0 Luciferase-like monooxygenase Ribosomal_L14 PF00238.19 ORY15203.1 - 8.1e-49 164.8 1.9 9e-49 164.6 1.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Phage_antitermQ PF06530.12 ORY15203.1 - 0.16 11.9 0.1 0.3 11.0 0.1 1.4 1 0 0 1 1 1 0 Phage antitermination protein Q RNA_POL_M_15KD PF02150.16 ORY15204.1 - 1.2e-09 37.9 2.3 1.2e-09 37.9 2.3 3.1 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit Nudix_N_2 PF14803.6 ORY15204.1 - 0.00035 20.4 7.0 0.34 10.8 0.5 3.4 3 0 0 3 3 3 3 Nudix N-terminal FYVE PF01363.21 ORY15204.1 - 0.013 15.6 4.1 1.9 8.7 0.2 2.2 2 0 0 2 2 2 0 FYVE zinc finger C1_1 PF00130.22 ORY15204.1 - 0.11 12.4 0.6 0.11 12.4 0.6 2.5 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) GFA PF04828.14 ORY15204.1 - 0.24 11.7 7.3 1.3 9.4 0.4 2.8 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme DZR PF12773.7 ORY15204.1 - 0.91 9.6 11.7 1.2 9.2 2.6 2.6 2 2 0 2 2 2 0 Double zinc ribbon zinc_ribbon_2 PF13240.6 ORY15204.1 - 1.1 9.1 10.3 10 6.0 3.7 3.4 2 1 0 2 2 2 0 zinc-ribbon domain C1_2 PF03107.16 ORY15204.1 - 9.2 6.7 12.1 11 6.4 1.7 3.4 2 2 0 2 2 2 0 C1 domain Rotamase PF00639.21 ORY15205.1 - 2.4e-24 86.1 0.1 3.2e-24 85.7 0.1 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 ORY15205.1 - 8.5e-19 68.2 0.0 1.1e-18 67.9 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.26 ORY15205.1 - 3.1e-08 33.6 2.8 3.1e-08 33.6 2.8 1.8 2 0 0 2 2 2 1 WW domain Rotamase_2 PF13145.6 ORY15205.1 - 6.4e-06 27.0 0.0 9.7e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 PPIC-type PPIASE domain DnaG_DnaB_bind PF08278.11 ORY15207.1 - 0.04 14.5 0.7 0.07 13.7 0.7 1.3 1 0 0 1 1 1 0 DNA primase DnaG DnaB-binding CorA PF01544.18 ORY15209.1 - 2.5e-09 36.9 0.1 4.2e-09 36.1 0.1 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Peptidase_M14 PF00246.24 ORY15212.1 - 6.4e-73 246.1 0.0 9e-73 245.6 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase Sec7 PF01369.20 ORY15213.1 - 1.2e-31 109.8 0.1 1.9e-31 109.2 0.1 1.2 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.6 ORY15213.1 - 0.00046 20.6 0.1 0.001 19.4 0.1 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 ORY15213.1 - 0.0011 19.4 0.0 0.0026 18.3 0.0 1.7 1 0 0 1 1 1 1 PH domain DUF1541 PF07563.11 ORY15213.1 - 0.22 11.4 0.0 0.55 10.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1541) adh_short_C2 PF13561.6 ORY15214.1 - 1.7e-41 142.3 0.0 1.6e-40 139.1 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY15214.1 - 1.3e-39 135.7 0.2 3.9e-38 130.9 0.2 2.1 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORY15214.1 - 8.8e-07 29.0 0.0 1.4e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 ORY15214.1 - 0.12 11.5 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Epimerase PF01370.21 ORY15214.1 - 0.19 11.1 0.0 0.34 10.3 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Dynamin_N PF00350.23 ORY15215.1 - 0.00025 21.2 0.0 0.00074 19.6 0.0 1.9 1 0 0 1 1 1 1 Dynamin family AAA_16 PF13191.6 ORY15215.1 - 0.039 14.3 0.0 0.22 11.9 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain MMR_HSR1 PF01926.23 ORY15215.1 - 0.11 12.6 0.0 21 5.3 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase Cas_NE0113 PF09623.10 ORY15217.1 - 0.068 12.9 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 CRISPR-associated protein NE0113 (Cas_NE0113) Cofilin_ADF PF00241.20 ORY15218.1 - 3.8e-10 39.6 0.0 1.4e-08 34.6 0.0 2.2 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein Fn3-like PF14310.6 ORY15219.1 - 2.5e-25 88.4 0.0 3.9e-25 87.8 0.0 1.3 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF3450 PF11932.8 ORY15219.1 - 0.03 13.6 0.1 0.039 13.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Glyco_hydro_3 PF00933.21 ORY15219.1 - 0.1 11.9 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 N terminal domain DUF308 PF03729.13 ORY15233.1 - 0.43 10.9 6.7 0.14 12.5 2.0 2.5 2 0 0 2 2 2 0 Short repeat of unknown function (DUF308) Phage_holin_3_6 PF07332.11 ORY15233.1 - 2.9 8.0 7.6 0.35 10.9 1.7 2.2 1 1 1 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III DUF1664 PF07889.12 ORY15234.1 - 0.0019 18.2 10.5 0.0078 16.2 5.7 3.3 3 1 0 3 3 3 1 Protein of unknown function (DUF1664) Spc7 PF08317.11 ORY15234.1 - 0.03 13.2 8.5 0.053 12.4 8.5 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein OmpH PF03938.14 ORY15234.1 - 0.1 12.9 9.5 1.5 9.2 7.9 2.5 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DivIVA PF05103.13 ORY15234.1 - 0.12 12.4 11.4 0.23 11.6 10.7 1.7 2 0 0 2 2 2 0 DivIVA protein FAM76 PF16046.5 ORY15234.1 - 0.16 11.3 5.8 0.34 10.2 5.8 1.6 1 0 0 1 1 1 0 FAM76 protein SOBP PF15279.6 ORY15234.1 - 0.35 11.5 3.0 0.48 11.0 3.0 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein V_ATPase_I PF01496.19 ORY15234.1 - 0.4 8.5 3.9 0.52 8.2 3.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ATG16 PF08614.11 ORY15234.1 - 0.59 10.3 12.7 0.95 9.7 8.8 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) CorA PF01544.18 ORY15234.1 - 1.3 8.2 13.2 15 4.8 7.2 3.2 3 1 1 4 4 4 0 CorA-like Mg2+ transporter protein DUF4559 PF15112.6 ORY15234.1 - 1.5 8.4 9.9 5.4 6.6 9.9 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4559) FliD_N PF02465.18 ORY15234.1 - 3.9 8.2 6.6 4.7 8.0 5.1 2.0 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DUF724 PF05266.14 ORY15234.1 - 4.3 7.1 18.0 0.2 11.5 8.9 2.7 2 2 1 3 3 3 0 Protein of unknown function (DUF724) Seryl_tRNA_N PF02403.22 ORY15234.1 - 7.3 6.9 13.3 2 8.7 6.3 3.0 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Fib_alpha PF08702.10 ORY15234.1 - 9.7 6.4 12.1 2.5 8.3 7.9 2.3 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family HSP70 PF00012.20 ORY15235.1 - 1.7e-07 29.9 0.0 3.1e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 ORY15235.1 - 0.00016 20.6 0.2 0.0013 17.6 0.1 2.0 2 0 0 2 2 2 1 MreB/Mbl protein PE_PPE_C PF12484.8 ORY15235.1 - 0.14 13.1 0.1 0.66 10.9 0.0 2.1 2 0 0 2 2 2 0 Polymorphic PE/PPE proteins C terminal GTP_EFTU PF00009.27 ORY15236.1 - 2e-57 193.9 0.0 2.9e-57 193.3 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 ORY15236.1 - 2.8e-14 52.9 0.0 1.1e-13 51.0 0.0 2.0 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 ORY15236.1 - 1.2e-10 41.6 0.0 3.2e-10 40.3 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 ORY15236.1 - 8.2e-08 32.2 0.0 2e-07 31.0 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.18 ORY15236.1 - 0.0056 16.5 0.0 0.079 12.7 0.0 2.5 2 0 0 2 2 2 1 Elongation factor G, domain IV MMR_HSR1 PF01926.23 ORY15236.1 - 0.063 13.4 0.0 0.18 11.9 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase PH PF00169.29 ORY15237.1 - 1.4e-27 96.3 0.7 6.1e-14 52.4 0.3 2.3 2 0 0 2 2 2 2 PH domain PH_11 PF15413.6 ORY15237.1 - 5.4e-09 36.4 4.4 0.0042 17.5 2.1 4.0 2 2 0 2 2 2 2 Pleckstrin homology domain PH_9 PF15410.6 ORY15237.1 - 1e-07 32.4 0.9 0.0049 17.2 0.0 3.7 2 2 0 2 2 2 2 Pleckstrin homology domain PH_8 PF15409.6 ORY15237.1 - 5.3e-05 23.4 0.2 0.00062 20.0 0.0 2.2 2 0 0 2 2 2 1 Pleckstrin homology domain PH_13 PF16652.5 ORY15237.1 - 0.02 14.7 0.3 0.17 11.7 0.1 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain Mcp5_PH PF12814.7 ORY15237.1 - 0.033 14.3 0.2 1.2 9.2 0.0 2.3 2 0 0 2 2 2 0 Meiotic cell cortex C-terminal pleckstrin homology PH_10 PF15411.6 ORY15237.1 - 0.046 14.0 0.1 7.9 6.8 0.0 2.5 2 0 0 2 2 2 0 Pleckstrin homology domain PH_12 PF16457.5 ORY15237.1 - 0.054 14.0 0.7 12 6.5 0.0 3.0 2 1 0 2 2 2 0 Pleckstrin homology domain PH_2 PF08458.10 ORY15237.1 - 0.087 13.2 0.2 5.8 7.3 0.0 2.4 2 0 0 2 2 2 0 Plant pleckstrin homology-like region DUF3237 PF11578.8 ORY15238.1 - 1.3e-19 70.5 0.0 1.4e-19 70.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) Abhydrolase_6 PF12697.7 ORY15239.1 - 1.2e-13 52.2 0.6 1.5e-13 51.8 0.6 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ORY15239.1 - 4.2e-13 49.5 0.0 2.8e-11 43.6 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ORY15239.1 - 2.5e-10 40.0 0.0 7.1e-08 32.0 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 ORY15239.1 - 7.1e-05 22.9 0.0 0.00058 19.9 0.0 2.1 2 0 0 2 2 2 1 TAP-like protein FSH1 PF03959.13 ORY15239.1 - 0.00061 19.5 0.0 0.0052 16.5 0.0 2.0 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Peptidase_S9 PF00326.21 ORY15239.1 - 0.00065 19.2 0.0 0.012 15.1 0.0 2.3 2 1 0 2 2 2 1 Prolyl oligopeptidase family DLH PF01738.18 ORY15239.1 - 0.033 13.7 0.0 1 8.9 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family BAAT_C PF08840.11 ORY15239.1 - 0.061 13.2 0.0 0.22 11.4 0.0 1.8 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal PGAP1 PF07819.13 ORY15239.1 - 0.07 12.8 0.0 0.19 11.4 0.0 1.7 1 1 0 1 1 1 0 PGAP1-like protein Esterase PF00756.20 ORY15239.1 - 0.12 12.1 0.1 0.31 10.6 0.0 1.7 2 0 0 2 2 2 0 Putative esterase CENP-Q PF13094.6 ORY15240.1 - 0.0012 19.1 0.0 0.0012 19.1 0.0 3.2 2 1 1 3 3 3 1 CENP-Q, a CENPA-CAD centromere complex subunit Helo_like_N PF17111.5 ORY15240.1 - 0.0012 18.3 0.1 0.0012 18.3 0.1 3.3 2 2 1 3 3 3 1 Fungal N-terminal domain of STAND proteins BAR_3 PF16746.5 ORY15240.1 - 0.011 15.4 16.6 0.0098 15.6 8.1 2.6 2 1 0 2 2 2 0 BAR domain of APPL family CC2-LZ PF16516.5 ORY15240.1 - 0.025 14.9 5.3 0.025 14.9 5.3 3.3 2 1 1 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator MAT1 PF06391.13 ORY15240.1 - 0.046 13.6 20.3 0.013 15.3 13.4 2.3 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 DUF1759 PF03564.15 ORY15240.1 - 0.53 10.2 6.8 2.9 7.8 1.9 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1759) ABC_tran_CTD PF16326.5 ORY15240.1 - 0.62 10.3 20.7 0.23 11.7 1.4 3.8 3 2 3 6 6 6 0 ABC transporter C-terminal domain FUSC PF04632.12 ORY15240.1 - 3.4 6.1 5.3 4.7 5.6 3.4 1.9 2 0 0 2 2 2 0 Fusaric acid resistance protein family DUF1664 PF07889.12 ORY15240.1 - 6.2 6.9 14.7 14 5.8 0.1 4.0 2 2 2 4 4 4 0 Protein of unknown function (DUF1664) DUF148 PF02520.17 ORY15240.1 - 6.3 7.0 12.8 1.3 9.2 4.1 3.3 3 0 0 3 3 3 0 Domain of unknown function DUF148 DUF349 PF03993.12 ORY15240.1 - 8.6 6.7 18.6 1.8 8.9 7.5 3.9 4 1 1 5 5 4 0 Domain of Unknown Function (DUF349) Cauli_AT PF03233.13 ORY15240.1 - 8.9 6.2 13.0 2.1 8.3 3.5 3.2 2 2 1 3 3 3 0 Aphid transmission protein E1-E2_ATPase PF00122.20 ORY15241.1 - 0.12 11.9 0.0 0.13 11.8 0.0 1.0 1 0 0 1 1 1 0 E1-E2 ATPase DUF1445 PF07286.12 ORY15242.1 - 0.19 11.7 0.0 0.28 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1445) DUF3597 PF12200.8 ORY15243.1 - 9.1e-11 42.4 0.8 2e-10 41.3 0.7 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3597) zf-CCHC PF00098.23 ORY15243.1 - 0.023 14.8 1.3 0.023 14.8 1.3 2.9 3 0 0 3 3 3 0 Zinc knuckle HET PF06985.11 ORY15243.1 - 0.046 14.1 0.7 0.16 12.3 0.7 2.0 1 0 0 1 1 1 0 Heterokaryon incompatibility protein (HET) PNP_phzG_C PF10590.9 ORY15243.1 - 0.073 13.2 0.0 0.3 11.2 0.0 2.2 1 0 0 1 1 1 0 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region zf-CCHC_5 PF14787.6 ORY15243.1 - 0.34 10.7 14.8 1.3 8.8 8.6 2.6 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger CorA PF01544.18 ORY15245.1 - 7e-13 48.5 0.1 1.5e-12 47.4 0.1 1.5 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein FAD_binding_4 PF01565.23 ORY15247.1 - 9.2e-16 57.8 0.1 1.6e-15 57.1 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 ORY15247.1 - 1.3e-12 47.6 0.1 4.2e-12 46.0 0.1 1.9 2 0 0 2 2 2 1 Berberine and berberine like CAF1C_H4-bd PF12265.8 ORY15249.1 - 1.9e-14 53.7 0.0 5e-14 52.3 0.0 1.8 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 ORY15249.1 - 5.9e-13 49.1 7.7 9.1e-06 26.3 0.0 3.8 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY15249.1 - 1.5e-07 31.6 1.8 0.00017 21.9 0.2 3.6 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain PALB2_WD40 PF16756.5 ORY15249.1 - 0.13 11.2 3.2 0.32 9.9 1.7 2.1 1 1 1 2 2 2 0 Partner and localizer of BRCA2 WD40 domain Ras PF00071.22 ORY15250.1 - 2.4e-31 108.5 0.2 3.4e-31 108.0 0.2 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY15250.1 - 1.3e-23 83.5 0.1 2.9e-23 82.4 0.1 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY15250.1 - 1.7e-06 27.6 0.1 2.3e-06 27.2 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 ORY15250.1 - 9.4e-05 21.9 0.2 0.00014 21.3 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DLIC PF05783.11 ORY15250.1 - 0.0055 15.6 0.1 0.66 8.7 0.0 2.2 2 0 0 2 2 2 2 Dynein light intermediate chain (DLIC) CrgA PF06781.12 ORY15250.1 - 0.082 13.0 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 Cell division protein CrgA G-alpha PF00503.20 ORY15250.1 - 0.57 9.3 4.0 0.62 9.2 0.1 2.5 1 1 2 3 3 3 0 G-protein alpha subunit EXOSC1 PF10447.9 ORY15251.1 - 1.6e-18 67.3 4.7 5.8e-12 46.2 1.1 2.3 1 1 1 2 2 2 2 Exosome component EXOSC1/CSL4 ECR1_N PF14382.6 ORY15251.1 - 4.7e-12 45.5 0.1 1.1e-11 44.3 0.1 1.6 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region Ilar_coat PF01787.16 ORY15252.1 - 0.032 14.0 0.0 0.073 12.9 0.0 1.5 1 0 0 1 1 1 0 Ilarvirus coat protein F-box-like PF12937.7 ORY15253.1 - 0.035 14.0 0.1 0.06 13.2 0.1 1.4 1 0 0 1 1 1 0 F-box-like F-box PF00646.33 ORY15253.1 - 0.075 12.9 0.1 0.15 12.0 0.1 1.5 1 0 0 1 1 1 0 F-box domain Zn_Tnp_IS1595 PF12760.7 ORY15253.1 - 0.2 11.7 3.5 2.8 8.0 0.6 2.4 2 0 0 2 2 2 0 Transposase zinc-ribbon domain PIG-L PF02585.17 ORY15254.1 - 8e-25 88.0 0.0 1.1e-24 87.5 0.0 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase DUF1304 PF06993.12 ORY15255.1 - 0.048 13.7 0.2 0.098 12.7 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1304) 7TM_GPCR_Sra PF02117.16 ORY15255.1 - 0.071 11.9 1.0 0.094 11.5 1.0 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Sra F-box-like PF12937.7 ORY15256.1 - 2e-05 24.4 0.8 6e-05 22.9 0.8 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY15256.1 - 0.08 12.8 0.1 0.18 11.7 0.1 1.6 1 0 0 1 1 1 0 F-box domain Fungal_trans PF04082.18 ORY15257.1 - 6.9e-10 38.4 1.0 3.9e-09 35.9 0.4 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY15257.1 - 1.1e-06 28.7 9.4 1.9e-06 27.9 9.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain F-box-like_2 PF13013.6 ORY15258.1 - 0.0017 18.3 0.0 0.0032 17.4 0.0 1.5 1 1 0 1 1 1 1 F-box-like domain YfiO PF13525.6 ORY15258.1 - 0.095 12.4 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Outer membrane lipoprotein SLAC1 PF03595.17 ORY15259.1 - 6e-93 311.7 54.3 6.8e-93 311.5 54.3 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel zf-C2H2_4 PF13894.6 ORY15260.1 - 0.023 15.5 21.5 0.055 14.3 0.1 4.6 5 0 0 5 5 5 0 C2H2-type zinc finger DZR PF12773.7 ORY15260.1 - 0.031 14.3 10.4 1.1 9.3 6.2 2.6 2 1 0 2 2 2 0 Double zinc ribbon zf-C2H2 PF00096.26 ORY15260.1 - 0.034 14.6 16.6 0.22 12.0 0.2 4.2 4 1 0 4 4 4 0 Zinc finger, C2H2 type zf-C2HC_2 PF13913.6 ORY15260.1 - 0.13 12.2 5.6 2.6 8.0 0.3 2.9 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.8 ORY15260.1 - 0.52 10.7 9.1 2.7 8.4 0.2 3.7 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Acetyltransf_1 PF00583.25 ORY15261.1 - 5.5e-08 33.0 0.1 8.6e-08 32.4 0.1 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ORY15261.1 - 4.2e-05 23.9 0.0 6.3e-05 23.3 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ORY15261.1 - 0.00088 19.2 0.0 0.0014 18.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 ORY15261.1 - 0.039 14.1 0.0 0.075 13.2 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Nha1_C PF08619.10 ORY15262.1 - 8.4e-100 335.2 51.5 8.7e-97 325.2 37.2 2.4 2 1 1 3 3 3 2 Alkali metal cation/H+ antiporter Nha1 C terminus Na_H_Exchanger PF00999.21 ORY15262.1 - 7.5e-78 262.0 22.5 8.9e-78 261.7 22.5 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.6 ORY15262.1 - 0.46 10.6 3.4 0.36 10.9 0.4 2.3 2 0 0 2 2 2 0 YrhC-like protein PRP4 PF08799.11 ORY15262.1 - 8 6.1 13.2 5.7 6.6 0.8 3.6 3 0 0 3 3 3 0 pre-mRNA processing factor 4 (PRP4) like Arrestin_C PF02752.22 ORY15263.1 - 1.1e-20 74.5 0.2 8.4e-20 71.6 0.2 2.3 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 ORY15263.1 - 4.7e-10 39.7 0.0 3.5e-05 23.9 0.0 2.4 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Pcc1 PF09341.10 ORY15263.1 - 0.16 12.1 0.0 0.58 10.3 0.0 2.0 2 0 0 2 2 2 0 Transcription factor Pcc1 PTCB-BRCT PF12738.7 ORY15265.1 - 1.8e-44 149.5 1.5 1.4e-23 82.6 0.4 3.8 4 0 0 4 4 4 3 twin BRCT domain BRCT PF00533.26 ORY15265.1 - 4e-34 116.8 0.1 2.1e-14 53.7 0.0 4.5 4 0 0 4 4 4 4 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 ORY15265.1 - 9.8e-11 41.9 0.0 0.00048 20.5 0.0 4.2 4 0 0 4 4 4 2 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 ORY15265.1 - 5.5e-06 26.6 0.3 0.31 11.4 0.0 3.6 3 0 0 3 3 3 2 DNA ligase 3 BRCT domain BRCT_3 PF18428.1 ORY15265.1 - 7.6e-06 25.9 0.1 0.024 14.7 0.0 3.6 4 0 0 4 4 4 2 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_5 PF16770.5 ORY15265.1 - 0.00055 19.8 0.0 0.063 13.2 0.0 3.6 4 0 0 4 4 4 1 Regulator of Ty1 transposition protein 107 BRCT domain DIOX_N PF14226.6 ORY15266.1 - 1.4e-21 77.4 0.0 4.7e-21 75.7 0.0 1.7 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 ORY15266.1 - 9.5e-18 64.6 0.0 2e-17 63.6 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF676 PF05057.14 ORY15267.1 - 7.2e-09 35.5 0.0 1.2e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) NACHT PF05729.12 ORY15267.1 - 2e-06 27.8 0.0 4.5e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 ORY15267.1 - 5.6e-05 23.4 0.0 0.0017 18.6 0.0 3.0 2 0 0 2 2 2 1 AAA domain PGAP1 PF07819.13 ORY15267.1 - 0.00025 20.8 0.0 0.00044 20.0 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein AAA_16 PF13191.6 ORY15267.1 - 0.00061 20.2 0.0 0.0024 18.3 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain Rad17 PF03215.15 ORY15267.1 - 0.025 14.5 0.0 0.075 12.9 0.0 1.7 2 0 0 2 2 2 0 Rad17 P-loop domain Abhydrolase_6 PF12697.7 ORY15267.1 - 0.029 15.0 0.2 0.09 13.4 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase family ABC_tran PF00005.27 ORY15267.1 - 0.056 14.0 0.0 0.11 13.0 0.0 1.6 1 0 0 1 1 1 0 ABC transporter ATPase PF06745.13 ORY15267.1 - 0.11 11.8 0.0 0.25 10.6 0.0 1.5 1 0 0 1 1 1 0 KaiC DUF2075 PF09848.9 ORY15267.1 - 0.15 11.2 0.0 0.49 9.6 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) NB-ARC PF00931.22 ORY15267.1 - 0.17 11.0 0.0 0.38 9.9 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain DUF3425 PF11905.8 ORY15268.1 - 6.7e-18 64.9 0.3 2.8e-17 62.8 0.3 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 ORY15268.1 - 0.018 15.1 5.7 0.042 13.9 5.7 1.5 1 0 0 1 1 1 0 bZIP transcription factor DUF4349 PF14257.6 ORY15268.1 - 0.1 12.1 1.4 0.16 11.4 1.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) CASP_C PF08172.12 ORY15268.1 - 0.15 11.4 5.3 0.22 10.8 5.3 1.1 1 0 0 1 1 1 0 CASP C terminal Abhydrolase_3 PF07859.13 ORY15269.1 - 3.4e-26 92.4 0.0 5.6e-26 91.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 ORY15269.1 - 1e-18 67.4 0.0 1.5e-18 66.9 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase DUF2974 PF11187.8 ORY15269.1 - 0.049 13.2 0.0 0.079 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Methyltransf_25 PF13649.6 ORY15270.1 - 8.1e-09 36.1 0.0 1.3e-08 35.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY15270.1 - 2.6e-06 28.0 0.0 4.5e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORY15270.1 - 0.0031 16.9 0.0 0.0091 15.4 0.0 1.6 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 ORY15270.1 - 0.023 15.5 0.0 0.049 14.4 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Pkinase PF00069.25 ORY15271.1 - 5.3e-29 101.4 0.0 8.9e-29 100.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY15271.1 - 9.2e-17 61.2 0.0 1.9e-16 60.1 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase dsrm PF00035.26 ORY15271.1 - 0.12 13.1 0.0 0.25 12.0 0.0 1.6 1 0 0 1 1 1 0 Double-stranded RNA binding motif DND1_DSRM PF14709.7 ORY15271.1 - 0.2 11.9 1.4 0.23 11.7 0.0 1.8 2 0 0 2 2 2 0 double strand RNA binding domain from DEAD END PROTEIN 1 Uds1 PF15456.6 ORY15272.1 - 0.3 11.3 7.1 0.065 13.4 2.6 2.3 2 0 0 2 2 2 0 Up-regulated During Septation PBP_sp32 PF07222.12 ORY15272.1 - 0.31 10.5 2.8 0.71 9.3 2.8 1.5 1 0 0 1 1 1 0 Proacrosin binding protein sp32 DUF4407 PF14362.6 ORY15272.1 - 1.1 8.5 10.9 0.038 13.3 4.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) RRM_1 PF00076.22 ORY15273.1 - 4e-14 52.2 0.0 9.3e-14 51.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Hamartin PF04388.12 ORY15273.1 - 2 7.0 7.7 2.5 6.6 7.7 1.1 1 0 0 1 1 1 0 Hamartin protein GPS2_interact PF15784.5 ORY15274.1 - 0.00034 21.0 2.3 0.0006 20.2 2.3 1.4 1 0 0 1 1 1 1 G-protein pathway suppressor 2-interacting domain Tim17 PF02466.19 ORY15274.1 - 0.025 15.0 5.0 0.3 11.5 5.0 2.2 1 1 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family Rick_17kDa_Anti PF05433.15 ORY15274.1 - 1.8 8.5 13.5 0.68 9.9 0.3 2.5 2 1 0 2 2 2 0 Glycine zipper 2TM domain adh_short_C2 PF13561.6 ORY15275.1 - 3.6e-66 223.1 1.9 4.1e-66 222.9 1.9 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY15275.1 - 3.7e-49 166.8 2.4 4.3e-49 166.6 2.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORY15275.1 - 2.2e-12 47.2 0.8 3.3e-12 46.7 0.8 1.2 1 0 0 1 1 1 1 KR domain Ldh_1_N PF00056.23 ORY15275.1 - 0.031 14.4 0.1 0.061 13.4 0.1 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain ADH_zinc_N PF00107.26 ORY15276.1 - 8.2e-21 74.3 0.4 1.6e-20 73.4 0.4 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ORY15276.1 - 5.2e-17 61.7 0.7 1e-16 60.8 0.7 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.18 ORY15276.1 - 6.7e-06 26.3 0.1 1.1e-05 25.7 0.1 1.3 1 0 0 1 1 1 1 TrkA-N domain AlaDh_PNT_C PF01262.21 ORY15276.1 - 0.00018 20.9 1.2 0.00026 20.4 0.1 1.7 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 ORY15276.1 - 0.00085 18.7 0.0 0.0017 17.8 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_25 PF13649.6 ORY15276.1 - 0.0014 19.3 0.0 0.0046 17.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY15276.1 - 0.0089 16.7 0.1 0.024 15.3 0.1 1.8 1 0 0 1 1 1 1 Methyltransferase domain UDPG_MGDP_dh_N PF03721.14 ORY15276.1 - 0.013 15.1 0.2 0.026 14.1 0.2 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain PglD_N PF17836.1 ORY15276.1 - 0.016 15.8 0.2 0.032 14.9 0.2 1.5 1 0 0 1 1 1 0 PglD N-terminal domain XdhC_C PF13478.6 ORY15276.1 - 0.048 14.2 0.0 0.088 13.3 0.0 1.4 1 0 0 1 1 1 0 XdhC Rossmann domain 3HCDH_N PF02737.18 ORY15276.1 - 0.057 13.3 0.2 0.11 12.4 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain CMAS PF02353.20 ORY15276.1 - 0.09 12.1 0.1 0.13 11.5 0.1 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase ThiF PF00899.21 ORY15276.1 - 0.09 12.1 0.3 0.16 11.3 0.3 1.4 1 0 0 1 1 1 0 ThiF family Cofac_haem_bdg PF04187.13 ORY15276.1 - 0.093 12.7 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 Haem-binding uptake, Tiki superfamily, ChaN adh_short PF00106.25 ORY15277.1 - 6.9e-40 136.6 0.2 8.6e-40 136.3 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY15277.1 - 4.2e-25 88.7 0.2 5.6e-25 88.3 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY15277.1 - 1.7e-10 41.1 0.4 2.3e-10 40.7 0.4 1.1 1 0 0 1 1 1 1 KR domain 2-Hacid_dh_C PF02826.19 ORY15277.1 - 0.035 13.5 0.0 0.07 12.5 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 ORY15277.1 - 0.1 13.1 0.0 0.21 12.0 0.0 1.6 2 0 0 2 2 2 0 Putative NAD(P)-binding Polysacc_synt_2 PF02719.15 ORY15277.1 - 0.11 11.6 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Glyoxalase PF00903.25 ORY15279.1 - 2.6e-14 53.5 0.0 4.3e-14 52.8 0.0 1.3 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 ORY15279.1 - 3e-12 46.8 0.0 3.7e-12 46.5 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 ORY15279.1 - 8e-09 36.2 0.0 2.1e-08 34.9 0.0 1.6 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_3 PF13468.6 ORY15279.1 - 0.00045 20.4 0.0 0.0019 18.4 0.0 1.8 1 1 0 1 1 1 1 Glyoxalase-like domain p450 PF00067.22 ORY15280.1 - 2.6e-64 217.7 0.0 3.5e-64 217.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 AtuA PF07287.11 ORY15281.1 - 8.9e-127 422.6 0.0 1.1e-126 422.4 0.0 1.1 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA DUF5371 PF17341.2 ORY15281.1 - 0.13 12.5 0.1 0.59 10.4 0.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5371) EthD PF07110.11 ORY15282.1 - 1.2e-16 61.6 0.5 1.3e-16 61.5 0.5 1.0 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 ORY15282.1 - 5.2e-06 26.9 0.2 6e-06 26.7 0.2 1.2 1 0 0 1 1 1 1 Methylmuconolactone methyl-isomerase Aldo_ket_red PF00248.21 ORY15283.1 - 2.9e-75 253.2 0.0 3.3e-75 253.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family TRI12 PF06609.13 ORY15284.1 - 3e-69 234.0 24.3 4e-69 233.6 24.3 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 ORY15284.1 - 4.5e-16 58.7 65.5 1.8e-15 56.7 58.8 3.1 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY15284.1 - 3e-09 36.3 29.4 1.6e-08 33.9 16.5 3.3 3 0 0 3 3 3 2 Sugar (and other) transporter Pox_A14 PF05767.12 ORY15284.1 - 0.0074 16.4 0.1 0.0074 16.4 0.1 2.8 2 1 1 3 3 3 1 Poxvirus virion envelope protein A14 DUF3413 PF11893.8 ORY15284.1 - 0.093 11.9 0.1 0.093 11.9 0.1 2.8 2 1 0 3 3 3 0 Domain of unknown function (DUF3413) adh_short_C2 PF13561.6 ORY15285.1 - 2.2e-32 112.5 0.4 5.7e-32 111.1 0.4 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY15285.1 - 1.1e-29 103.3 0.1 2e-29 102.5 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORY15285.1 - 3.6e-09 36.8 2.2 1.7e-08 34.6 0.1 2.1 2 0 0 2 2 2 1 KR domain Sacchrp_dh_NADP PF03435.18 ORY15285.1 - 0.0023 18.2 0.2 0.0038 17.5 0.2 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 ORY15285.1 - 0.028 13.9 0.1 0.58 9.6 0.0 2.2 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 ORY15285.1 - 0.071 13.0 0.6 0.25 11.2 0.6 1.8 1 1 0 1 1 1 0 NAD(P)H-binding Polysacc_synt_2 PF02719.15 ORY15285.1 - 0.084 12.0 1.4 0.094 11.8 0.1 1.6 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Shikimate_DH PF01488.20 ORY15285.1 - 0.15 12.1 0.0 0.25 11.4 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase MFS_1 PF07690.16 ORY15286.1 - 1.3e-40 139.5 56.1 3.5e-39 134.7 53.9 2.9 2 1 0 2 2 2 2 Major Facilitator Superfamily GFO_IDH_MocA PF01408.22 ORY15287.1 - 1.3e-17 64.7 0.0 2.1e-17 64.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 ORY15287.1 - 0.00011 22.2 0.0 0.0002 21.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain PATR PF12951.7 ORY15287.1 - 0.1 12.7 0.5 0.21 11.7 0.5 1.6 1 0 0 1 1 1 0 Passenger-associated-transport-repeat Semialdhyde_dh PF01118.24 ORY15287.1 - 0.15 12.5 0.0 0.42 11.1 0.0 1.7 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain PseudoU_synth_2 PF00849.22 ORY15289.1 - 2.1e-27 96.2 0.0 3.3e-27 95.5 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 ORY15289.1 - 0.00013 21.6 0.0 0.00025 20.7 0.0 1.4 1 0 0 1 1 1 1 S4 domain Auto_anti-p27 PF06677.12 ORY15289.1 - 0.012 15.8 0.1 0.027 14.6 0.1 1.5 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) 4HBT PF03061.22 ORY15290.1 - 4e-09 36.7 0.0 5.4e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_2 PF13279.6 ORY15290.1 - 1.2e-05 25.8 0.0 1.5e-05 25.5 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.17 ORY15290.1 - 3.4e-05 23.3 1.1 0.00026 20.4 1.4 1.9 1 1 1 2 2 2 1 Acyl-ACP thioesterase peroxidase PF00141.23 ORY15291.1 - 4.8e-25 88.6 0.0 7.3e-25 88.0 0.0 1.2 1 0 0 1 1 1 1 Peroxidase Peroxidase_ext PF11895.8 ORY15291.1 - 0.013 15.4 0.0 0.028 14.4 0.0 1.5 1 0 0 1 1 1 0 Fungal peroxidase extension region Rod-binding PF10135.9 ORY15291.1 - 0.19 12.3 0.9 0.73 10.5 0.1 2.3 2 0 0 2 2 2 0 Rod binding protein SET PF00856.28 ORY15292.1 - 2.6e-10 41.0 0.0 4.9e-10 40.1 0.0 1.7 1 1 0 1 1 1 1 SET domain TPR_10 PF13374.6 ORY15292.1 - 0.17 11.8 0.2 0.38 10.7 0.2 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Urb2 PF10441.9 ORY15293.1 - 3.2e-53 180.7 5.2 4.8e-53 180.2 0.0 3.4 4 0 0 4 4 4 1 Urb2/Npa2 family DUF543 PF04418.12 ORY15294.1 - 5.9e-30 103.1 0.0 6.8e-30 102.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) Glyco_hydro_61 PF03443.14 ORY15297.1 - 5.5e-65 219.1 1.6 6.6e-65 218.9 1.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Methyltransf_2 PF00891.18 ORY15299.1 - 1e-11 44.5 0.0 6.8e-10 38.6 0.0 2.0 1 1 1 2 2 2 2 O-methyltransferase domain Glyco_hydro_11 PF00457.17 ORY15300.1 - 2e-47 161.1 17.4 2.6e-47 160.8 17.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 Ank_2 PF12796.7 ORY15301.1 - 0.1 13.2 0.0 0.27 11.8 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) HET PF06985.11 ORY15302.1 - 2.3e-23 83.2 0.0 6.1e-23 81.8 0.0 1.7 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PLAC8 PF04749.17 ORY15304.1 - 8.8e-23 81.2 14.0 1.4e-22 80.5 14.0 1.3 1 0 0 1 1 1 1 PLAC8 family TIP120 PF08623.10 ORY15306.1 - 3.4e-63 212.4 4.5 7.1e-62 208.1 0.1 3.9 4 0 0 4 4 4 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.6 ORY15306.1 - 1.6e-11 44.4 12.8 0.018 15.4 0.0 8.1 7 1 0 7 7 7 3 HEAT repeats HEAT PF02985.22 ORY15306.1 - 1.3e-06 28.2 20.1 3.4 8.2 0.1 10.5 11 0 0 11 11 11 2 HEAT repeat MMS19_C PF12460.8 ORY15306.1 - 6.4e-06 25.5 9.0 0.15 11.2 0.5 5.0 5 0 0 5 5 5 2 RNAPII transcription regulator C-terminal RTP1_C1 PF10363.9 ORY15306.1 - 2.5e-05 24.4 0.4 0.0042 17.2 0.0 4.2 4 0 0 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 ORY15306.1 - 2.9e-05 24.5 27.4 2.6 8.7 0.1 12.1 15 1 1 16 16 14 2 HEAT-like repeat Ecm29 PF13001.7 ORY15306.1 - 7.4e-05 21.6 1.0 0.0063 15.2 0.3 3.1 2 1 0 2 2 2 1 Proteasome stabiliser DUF3385 PF11865.8 ORY15306.1 - 0.00026 20.9 2.3 11 5.9 0.0 4.9 5 0 0 5 5 5 1 Domain of unknown function (DUF3385) DUF4042 PF13251.6 ORY15306.1 - 0.0055 16.4 0.7 35 4.0 0.0 5.3 4 2 1 5 5 5 0 Domain of unknown function (DUF4042) Cnd1 PF12717.7 ORY15306.1 - 0.011 15.7 8.5 0.11 12.5 0.1 4.9 5 1 1 6 6 6 0 non-SMC mitotic condensation complex subunit 1 Umbravirus_LDM PF04817.12 ORY15306.1 - 0.012 15.0 0.3 0.055 12.8 0.1 2.1 2 0 0 2 2 2 0 Umbravirus long distance movement (LDM) family Cnd3 PF12719.7 ORY15306.1 - 0.031 13.5 0.4 2.5 7.2 0.1 3.8 4 0 0 4 4 4 0 Nuclear condensing complex subunits, C-term domain Glyco_tran_28_C PF04101.16 ORY15306.1 - 0.06 13.3 0.0 0.15 12.0 0.0 1.7 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain E7 PF00527.18 ORY15306.1 - 3.7 7.8 4.6 3.1 8.1 0.3 2.6 1 1 1 2 2 2 0 E7 protein, Early protein DUF2263 PF10021.9 ORY15307.1 - 1.2e-11 45.2 0.0 2.6e-11 44.1 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) Macro PF01661.21 ORY15307.1 - 0.078 13.0 0.0 0.21 11.6 0.0 1.7 1 0 0 1 1 1 0 Macro domain NAD_kinase PF01513.21 ORY15308.1 - 2.6e-75 253.3 0.0 3.7e-75 252.8 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase CDRN PF05174.12 ORY15308.1 - 0.16 11.7 0.0 0.47 10.2 0.0 1.7 1 0 0 1 1 1 0 Cysteine-rich D. radiodurans N terminus AAA_lid_2 PF17863.1 ORY15309.1 - 4.1e-07 29.7 0.5 9.1e-06 25.4 0.3 2.8 3 0 0 3 3 3 1 AAA lid domain AAA_3 PF07726.11 ORY15309.1 - 0.012 15.4 0.0 0.022 14.6 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Porphobil_deam PF01379.20 ORY15311.1 - 1.4e-72 243.5 0.1 1.8e-72 243.2 0.1 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 ORY15311.1 - 1e-14 54.6 1.6 7.3e-09 35.9 0.2 2.5 2 0 0 2 2 2 2 Porphobilinogen deaminase, C-terminal domain p450 PF00067.22 ORY15312.1 - 2e-38 132.4 0.0 2.7e-38 131.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Ribonuclease PF00545.20 ORY15313.1 - 1.7e-09 38.3 0.1 2.4e-09 37.8 0.1 1.2 1 0 0 1 1 1 1 ribonuclease zf-MYND PF01753.18 ORY15315.1 - 1.6e-07 31.2 17.6 1.6e-07 31.2 17.6 2.9 2 0 0 2 2 2 1 MYND finger DUF816 PF05674.12 ORY15315.1 - 0.19 11.6 0.0 0.32 10.9 0.0 1.3 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF816) adh_short PF00106.25 ORY15317.1 - 4e-23 81.9 0.0 5.2e-23 81.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY15317.1 - 1e-14 54.7 0.0 1.6e-14 54.0 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY15317.1 - 5.8e-09 36.1 0.0 7.1e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ORY15317.1 - 3.3e-05 23.5 0.0 5.6e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 ORY15317.1 - 0.068 13.1 0.1 0.13 12.1 0.0 1.6 2 1 0 2 2 2 0 NAD(P)H-binding RmlD_sub_bind PF04321.17 ORY15317.1 - 0.2 10.7 0.1 0.4 9.7 0.0 1.5 2 0 0 2 2 2 0 RmlD substrate binding domain Fungal_lectin PF07938.12 ORY15318.1 - 2.1e-17 63.5 0.5 4e-11 42.8 0.1 2.5 1 1 1 2 2 2 2 Fungal fucose-specific lectin DUF3169 PF11368.8 ORY15318.1 - 0.13 11.8 0.1 0.2 11.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) Pilin_N PF07790.11 ORY15318.1 - 0.2 12.6 1.9 0.43 11.5 1.9 1.5 1 0 0 1 1 1 0 Archaeal Type IV pilin, N-terminal DnaJ PF00226.31 ORY15319.1 - 1.7e-19 69.7 0.6 4.1e-19 68.5 0.6 1.7 1 0 0 1 1 1 1 DnaJ domain RRM_1 PF00076.22 ORY15319.1 - 0.011 15.6 0.2 0.18 11.7 0.4 2.5 2 1 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Presenilin PF01080.17 ORY15319.1 - 3.7 6.2 3.7 5 5.8 3.7 1.2 1 0 0 1 1 1 0 Presenilin V_ATPase_I PF01496.19 ORY15319.1 - 4.5 5.1 4.7 6.1 4.6 4.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Macoilin PF09726.9 ORY15319.1 - 5.1 5.5 11.1 7.9 4.9 11.1 1.2 1 0 0 1 1 1 0 Macoilin family TruB_N PF01509.18 ORY15320.1 - 7.7e-46 156.2 0.0 1.8e-45 154.9 0.0 1.6 1 0 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 ORY15320.1 - 4.2e-06 26.8 0.0 1e-05 25.6 0.0 1.7 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain Trypan_PARP PF05887.11 ORY15320.1 - 0.011 15.7 9.6 0.011 15.7 9.6 2.4 3 0 0 3 3 3 0 Procyclic acidic repetitive protein (PARP) EamA PF00892.20 ORY15321.1 - 1.4e-10 41.5 31.2 7.5e-07 29.4 3.8 3.1 3 0 0 3 3 3 3 EamA-like transporter family SLC35F PF06027.12 ORY15321.1 - 1.2e-05 25.0 7.0 1.2e-05 25.0 7.0 1.7 2 0 0 2 2 2 1 Solute carrier family 35 PUNUT PF16913.5 ORY15321.1 - 2e-05 24.0 0.8 2e-05 24.0 0.8 2.7 3 0 0 3 3 3 1 Purine nucleobase transmembrane transport UAA PF08449.11 ORY15321.1 - 0.0039 16.4 7.5 0.0069 15.6 7.5 1.3 1 0 0 1 1 1 1 UAA transporter family CitMHS_2 PF16980.5 ORY15321.1 - 0.0041 15.8 0.4 0.011 14.5 0.0 1.8 2 0 0 2 2 2 1 Putative citrate transport DUF3955 PF13127.6 ORY15321.1 - 0.0045 16.8 1.2 0.0045 16.8 1.2 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF3955) DUF5518 PF17647.1 ORY15321.1 - 0.11 12.6 6.4 14 5.8 0.0 3.7 4 0 0 4 4 4 0 Family of unknown function (DUF5518) RNA_pol_Rpb1_R PF05001.13 ORY15321.1 - 0.44 11.0 5.7 0.25 11.8 1.0 2.8 3 0 0 3 3 3 0 RNA polymerase Rpb1 C-terminal repeat Sugar_transport PF06800.12 ORY15321.1 - 0.84 8.9 8.5 3.6 6.8 3.2 2.3 2 0 0 2 2 2 0 Sugar transport protein TMEM234 PF10639.9 ORY15321.1 - 3.4 7.7 7.5 1.8 8.6 0.2 3.0 3 0 0 3 3 3 0 Putative transmembrane family 234 Ras PF00071.22 ORY15322.1 - 9.5e-57 191.1 0.1 1.2e-56 190.8 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY15322.1 - 2.9e-32 111.4 0.0 4.2e-32 110.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY15322.1 - 2.2e-12 46.8 0.0 2.6e-12 46.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 ORY15322.1 - 1.1e-07 32.0 0.0 1.7e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 ORY15322.1 - 2.9e-06 26.8 0.0 3.5e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 ORY15322.1 - 1.3e-05 24.8 0.0 0.00064 19.3 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 ORY15322.1 - 7.6e-05 22.7 0.1 0.004 17.1 0.1 2.3 1 1 2 3 3 3 1 RsgA GTPase ATP_bind_1 PF03029.17 ORY15322.1 - 0.00026 20.9 0.4 0.0067 16.2 0.1 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein PduV-EutP PF10662.9 ORY15322.1 - 0.0023 17.7 0.1 0.12 12.1 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Septin PF00735.18 ORY15322.1 - 0.0059 15.9 0.1 0.062 12.6 0.0 2.1 2 0 0 2 2 2 1 Septin cobW PF02492.19 ORY15322.1 - 0.0069 16.0 0.0 0.034 13.7 0.0 1.8 1 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain SRPRB PF09439.10 ORY15322.1 - 0.0082 15.6 0.0 0.01 15.3 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 ORY15322.1 - 0.0086 16.4 0.0 0.016 15.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ORY15322.1 - 0.0094 16.4 0.0 0.02 15.3 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 ORY15322.1 - 0.01 15.8 0.0 0.015 15.3 0.0 1.5 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 ORY15322.1 - 0.022 14.5 0.0 0.038 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 ORY15322.1 - 0.025 14.1 0.1 0.044 13.3 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase_2 PF01637.18 ORY15322.1 - 0.072 13.0 0.3 0.14 12.1 0.1 1.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Glyco_hydro_75 PF07335.11 ORY15322.1 - 0.082 13.2 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Fungal chitosanase of glycosyl hydrolase group 75 TniB PF05621.11 ORY15322.1 - 0.12 11.7 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein NACHT PF05729.12 ORY15322.1 - 0.13 12.2 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 NACHT domain FeoB_N PF02421.18 ORY15322.1 - 0.13 11.8 0.0 1.6 8.2 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B NTPase_1 PF03266.15 ORY15322.1 - 0.16 11.9 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 NTPase Peptidase_S10 PF00450.22 ORY15324.1 - 8.7e-97 325.2 8.7 1.1e-96 324.9 8.7 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase MFS_1 PF07690.16 ORY15325.1 - 7.6e-24 84.3 47.1 7.6e-24 84.3 47.1 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily TRP PF06011.12 ORY15327.1 - 0.15 10.8 4.0 0.097 11.4 0.2 2.0 2 0 0 2 2 2 0 Transient receptor potential (TRP) ion channel DUF5325 PF17259.2 ORY15327.1 - 0.37 10.7 0.0 0.37 10.7 0.0 3.8 4 1 0 4 4 4 0 Family of unknown function (DUF5325) HisKA_7TM PF16927.5 ORY15327.1 - 1.1 9.2 11.0 2.1 8.3 11.0 1.4 1 1 0 1 1 1 0 N-terminal 7TM region of histidine kinase Claudin_2 PF13903.6 ORY15327.1 - 5.6 6.7 9.1 0.1 12.3 0.8 2.0 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction TctB PF07331.11 ORY15327.1 - 8.3 6.7 16.7 0.7 10.2 8.7 2.6 1 1 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family Fungal_trans_2 PF11951.8 ORY15328.1 - 1.5e-09 37.1 0.2 2.8e-09 36.3 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Metallophos PF00149.28 ORY15330.1 - 5.6e-10 40.1 0.3 8.1e-10 39.5 0.3 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 ORY15330.1 - 1.4e-07 31.9 0.4 2.8e-06 27.6 0.4 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain zf-CHY PF05495.12 ORY15331.1 - 3e-10 40.4 14.3 4.4e-10 39.9 14.3 1.2 1 0 0 1 1 1 1 CHY zinc finger Mu-like_Com PF10122.9 ORY15331.1 - 0.036 13.5 1.7 0.036 13.5 1.7 1.9 2 1 1 3 3 3 0 Mu-like prophage protein Com U1snRNP70_N PF12220.8 ORY15332.1 - 4.2e-19 69.0 0.2 8.1e-19 68.1 0.2 1.4 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.22 ORY15332.1 - 2.1e-14 53.1 0.0 4e-14 52.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 ORY15332.1 - 0.026 14.6 0.0 0.051 13.7 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif L51_S25_CI-B8 PF05047.16 ORY15333.1 - 1e-12 47.8 0.2 1.6e-12 47.1 0.2 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain 2-Hacid_dh_C PF02826.19 ORY15333.1 - 0.059 12.7 0.0 0.068 12.5 0.0 1.1 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TIM PF00121.18 ORY15334.1 - 1.5e-89 299.6 0.1 1.7e-89 299.4 0.1 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase S1 PF00575.23 ORY15336.1 - 4.4e-70 232.0 34.3 1.7e-12 47.5 2.4 12.8 13 0 0 13 13 13 11 S1 RNA binding domain RNase_II_C_S1 PF18614.1 ORY15336.1 - 2.1e-08 34.0 14.5 0.012 15.5 0.2 6.3 6 1 0 6 6 6 3 RNase II-type exonuclease C-terminal S1 domain Suf PF05843.14 ORY15336.1 - 0.00076 19.6 4.4 0.02 14.9 0.0 3.6 2 1 2 4 4 4 1 Suppressor of forked protein (Suf) TPR_14 PF13428.6 ORY15336.1 - 0.0023 18.6 2.1 5.2 8.1 0.6 4.5 4 1 1 5 5 5 1 Tetratricopeptide repeat NRDE-2 PF08424.10 ORY15336.1 - 0.027 13.6 0.2 0.22 10.6 0.3 2.4 2 1 0 2 2 2 0 NRDE-2, necessary for RNA interference S1_2 PF13509.6 ORY15336.1 - 0.062 13.4 0.1 1.1 9.4 0.0 3.3 3 0 0 3 3 3 0 S1 domain DUF3592 PF12158.8 ORY15336.1 - 0.062 13.4 0.1 13 5.8 0.0 3.8 4 1 0 4 4 4 0 Protein of unknown function (DUF3592) TPR_19 PF14559.6 ORY15336.1 - 0.086 13.4 0.1 0.6 10.6 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat WD40 PF00400.32 ORY15337.1 - 9.7e-18 64.2 14.5 2.8e-05 24.8 0.2 6.5 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY15337.1 - 1.5e-09 38.0 0.3 0.00079 19.7 0.1 4.9 4 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ORY15337.1 - 0.00081 18.2 0.5 0.11 11.1 0.0 2.2 1 1 1 2 2 2 2 Nucleoporin Nup120/160 WD40_like PF17005.5 ORY15337.1 - 0.012 15.0 0.1 0.057 12.7 0.0 1.9 2 0 0 2 2 2 0 WD40-like domain Ge1_WD40 PF16529.5 ORY15337.1 - 0.1 11.6 0.7 8.1 5.3 0.0 2.5 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein zf-C2H2_4 PF13894.6 ORY15338.1 - 2e-06 28.1 21.5 0.053 14.4 0.3 5.1 5 0 0 5 5 5 3 C2H2-type zinc finger zf-Di19 PF05605.12 ORY15338.1 - 2.6e-06 27.6 9.7 0.0088 16.3 2.0 3.4 3 0 0 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.26 ORY15338.1 - 2.7e-05 24.4 17.8 0.049 14.1 1.4 4.7 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_9 PF16293.5 ORY15338.1 - 0.016 15.1 2.9 0.028 14.2 0.1 2.7 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) DrsE_2 PF13686.6 ORY15338.1 - 0.09 12.7 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 DsrE/DsrF/DrsH-like family GAGA PF09237.11 ORY15338.1 - 0.14 12.0 4.5 0.21 11.4 0.1 2.8 2 1 1 3 3 3 0 GAGA factor zf-H2C2_2 PF13465.6 ORY15338.1 - 0.24 11.9 0.2 0.24 11.9 0.2 5.7 5 1 0 5 5 5 0 Zinc-finger double domain IBR PF01485.21 ORY15338.1 - 0.25 11.6 6.3 6.6 7.0 0.1 3.1 2 1 1 3 3 3 0 IBR domain, a half RING-finger domain FOXP-CC PF16159.5 ORY15338.1 - 0.3 11.7 6.4 13 6.5 0.4 3.5 2 1 1 3 3 3 0 FOXP coiled-coil domain DUF4729 PF15866.5 ORY15338.1 - 1.7 7.9 11.4 2.9 7.2 0.1 3.2 3 1 0 3 3 3 0 Domain of unknown function (DUF4729) TRI12 PF06609.13 ORY15339.1 - 3.9e-39 134.6 17.3 7.6e-29 100.6 4.5 2.0 1 1 1 2 2 2 2 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 ORY15339.1 - 1.8e-21 76.5 36.1 1.8e-21 76.5 36.1 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1611_N PF17396.2 ORY15339.1 - 0.15 12.3 0.1 0.31 11.3 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1611_N) Rossmann-like domain Ribosomal_S6 PF01250.17 ORY15340.1 - 6.4e-25 87.3 0.0 7.7e-25 87.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S6 GCV_H PF01597.19 ORY15341.1 - 4.3e-36 123.5 0.2 5.1e-36 123.2 0.2 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein ADH_zinc_N_2 PF13602.6 ORY15342.1 - 1.9e-23 83.9 0.5 3.9e-23 83.0 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 ORY15342.1 - 3.7e-14 52.8 0.1 6.3e-14 52.1 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Nup192 PF11894.8 ORY15343.1 - 0 1418.7 6.6 0 1418.5 6.6 1.0 1 0 0 1 1 1 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 Nup188 PF10487.9 ORY15343.1 - 0.013 13.5 0.9 0.025 12.5 0.3 1.8 2 0 0 2 2 2 0 Nucleoporin subcomplex protein binding to Pom34 PI3_PI4_kinase PF00454.27 ORY15344.1 - 4.2e-50 170.9 0.2 1.1e-49 169.6 0.0 1.8 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.8 ORY15344.1 - 2e-39 135.1 0.2 1.3e-38 132.5 0.2 2.6 1 0 0 1 1 1 1 Telomere-length maintenance and DNA damage repair FATC PF02260.20 ORY15344.1 - 2.4e-11 43.2 0.1 2e-09 37.1 0.0 3.3 3 0 0 3 3 3 1 FATC domain Mad3_BUB1_I PF08311.12 ORY15344.1 - 0.024 14.6 0.3 0.094 12.7 0.3 2.1 1 0 0 1 1 1 0 Mad3/BUB1 homology region 1 HEAT_2 PF13646.6 ORY15344.1 - 0.041 14.3 0.1 1.1 9.6 0.2 3.6 2 0 0 2 2 2 0 HEAT repeats MFS_1 PF07690.16 ORY15345.1 - 5.4e-35 120.9 28.8 5.4e-35 120.9 28.8 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 ORY15345.1 - 2.3e-06 27.2 1.4 2.3e-06 27.2 1.4 2.0 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Borrelia_P13 PF05628.12 ORY15345.1 - 0.13 12.2 5.8 7.1 6.6 0.7 3.3 3 0 0 3 3 3 0 Borrelia membrane protein P13 MFS_1 PF07690.16 ORY15347.1 - 0.00046 19.2 0.0 0.00051 19.1 0.0 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Peptidase_M19 PF01244.21 ORY15348.1 - 1.9e-78 263.9 0.0 2.2e-78 263.6 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) p450 PF00067.22 ORY15349.1 - 4.1e-07 29.1 0.0 5e-07 28.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Metallophos PF00149.28 ORY15350.1 - 1.7e-16 61.4 0.0 2.7e-16 60.7 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 ORY15350.1 - 1.6e-12 48.1 1.1 5.6e-12 46.3 0.3 2.4 2 0 0 2 2 2 1 Iron/zinc purple acid phosphatase-like protein C Pur_ac_phosph_N PF16656.5 ORY15350.1 - 9.3e-12 45.4 2.4 2.3e-11 44.1 2.4 1.6 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain PhoD_N PF16655.5 ORY15350.1 - 0.00019 21.9 0.3 0.0016 18.9 0.1 2.1 2 0 0 2 2 2 1 PhoD-like phosphatase, N-terminal domain Lactonase PF10282.9 ORY15351.1 - 2.7e-15 56.5 0.0 3.4e-15 56.1 0.0 1.2 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller SKG6 PF08693.10 ORY15352.1 - 0.0093 15.4 2.2 0.0093 15.4 2.2 1.8 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Lipase_3 PF01764.25 ORY15353.1 - 9.5e-36 122.8 0.0 1.3e-35 122.3 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Lipase3_N PF03893.16 ORY15353.1 - 3.1e-05 23.9 0.5 6.3e-05 22.9 0.5 1.5 1 0 0 1 1 1 1 Lipase 3 N-terminal region Abhydrolase_6 PF12697.7 ORY15353.1 - 6.1e-05 23.7 0.0 6.8e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 ORY15353.1 - 0.0028 17.3 0.0 0.73 9.3 0.1 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_8 PF06259.12 ORY15353.1 - 0.0032 17.1 0.0 0.0048 16.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase Hydrolase_4 PF12146.8 ORY15353.1 - 0.0037 16.5 0.0 0.0055 16.0 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 His_Phos_1 PF00300.22 ORY15353.1 - 0.0098 15.6 0.0 0.013 15.2 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF2974 PF11187.8 ORY15353.1 - 0.014 15.0 0.3 0.4 10.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) PGAP1 PF07819.13 ORY15353.1 - 0.015 15.0 0.0 0.024 14.4 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Esterase PF00756.20 ORY15353.1 - 0.028 14.1 0.1 0.06 13.0 0.0 1.5 2 0 0 2 2 2 0 Putative esterase Glyco_hydro_2_N PF02837.18 ORY15379.1 - 3e-16 59.8 0.0 5.2e-16 59.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.21 ORY15379.1 - 2.1e-15 57.4 0.1 3.8e-15 56.5 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_C PF02836.17 ORY15379.1 - 1.1e-08 34.6 0.0 3.5e-08 32.9 0.0 1.7 1 1 1 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain BetaGal_dom4_5 PF13364.6 ORY15379.1 - 0.0031 18.1 0.0 0.0078 16.8 0.0 1.7 1 0 0 1 1 1 1 Beta-galactosidase jelly roll domain ACBP PF00887.19 ORY15380.1 - 3.6e-22 78.4 0.0 8.1e-22 77.2 0.0 1.6 1 0 0 1 1 1 1 Acyl CoA binding protein Pkinase PF00069.25 ORY15381.1 - 4.9e-06 26.1 0.0 9.7e-06 25.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY15381.1 - 0.035 13.4 0.0 0.37 10.0 0.0 2.2 1 1 0 1 1 1 0 Protein tyrosine kinase Ank_2 PF12796.7 ORY15382.1 - 5.6e-21 74.9 0.4 1.2e-08 35.4 0.0 3.3 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ORY15382.1 - 1.4e-13 49.7 0.0 4.2e-05 23.6 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 ORY15382.1 - 1.8e-13 50.7 1.4 2.6e-06 27.8 0.0 4.0 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 ORY15382.1 - 3.4e-13 49.4 3.2 0.00023 21.5 0.1 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 ORY15382.1 - 2.1e-12 47.0 0.3 4.1e-05 23.8 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) NACHT PF05729.12 ORY15382.1 - 0.0011 18.9 0.1 0.0022 17.9 0.1 1.4 1 0 0 1 1 1 1 NACHT domain KAP_NTPase PF07693.14 ORY15382.1 - 0.13 11.5 0.1 0.2 10.9 0.1 1.3 1 0 0 1 1 1 0 KAP family P-loop domain Pkinase PF00069.25 ORY15383.1 - 4.1e-22 78.8 0.3 1.2e-13 51.1 0.0 2.9 2 1 0 2 2 2 2 Protein kinase domain Ank_2 PF12796.7 ORY15383.1 - 1.1e-19 70.8 0.1 6.8e-10 39.4 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Pkinase_Tyr PF07714.17 ORY15383.1 - 2.9e-10 39.9 0.0 3.2e-09 36.5 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Ank_4 PF13637.6 ORY15383.1 - 4.5e-07 30.3 0.0 3.9e-06 27.3 0.0 2.4 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 ORY15383.1 - 5.6e-07 29.7 0.0 2.2e-05 24.7 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 ORY15383.1 - 3e-06 27.2 0.0 0.00093 19.5 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 ORY15383.1 - 1.3e-05 25.4 0.0 0.00071 19.8 0.0 3.0 1 1 2 3 3 3 2 Ankyrin repeats (many copies) adh_short PF00106.25 ORY15384.1 - 1.2e-31 109.7 0.1 1.6e-31 109.3 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY15384.1 - 7.7e-26 91.1 0.3 1.2e-25 90.5 0.3 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY15384.1 - 7.6e-16 58.5 0.1 1.2e-15 57.9 0.1 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 ORY15384.1 - 4.3e-09 35.9 0.0 5.5e-09 35.6 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 ORY15384.1 - 3.3e-05 23.5 0.1 5.9e-05 22.6 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Pyr_redox_2 PF07992.14 ORY15384.1 - 0.032 13.5 0.0 0.044 13.0 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase RmlD_sub_bind PF04321.17 ORY15384.1 - 0.044 12.9 0.1 0.064 12.3 0.1 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain Pyr_redox PF00070.27 ORY15384.1 - 0.092 13.3 0.0 0.19 12.3 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GDP_Man_Dehyd PF16363.5 ORY15384.1 - 0.19 11.1 0.0 0.24 10.8 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase ThiF PF00899.21 ORY15384.1 - 0.2 11.0 1.5 3.3 7.0 0.1 2.1 2 0 0 2 2 2 0 ThiF family Zn_clus PF00172.18 ORY15385.1 - 2.2e-07 30.9 12.6 2.2e-07 30.9 12.6 2.2 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.26 ORY15385.1 - 0.0025 18.2 0.4 0.011 16.2 0.4 2.1 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY15385.1 - 0.12 13.3 0.6 0.56 11.2 0.6 2.3 1 0 0 1 1 1 0 C2H2-type zinc finger Kri1_C PF12936.7 ORY15387.1 - 8.1e-29 99.7 0.1 8.1e-29 99.7 0.1 3.7 4 1 1 5 5 5 1 KRI1-like family C-terminal Kri1 PF05178.12 ORY15387.1 - 1.8e-28 99.1 14.6 1.8e-28 99.1 14.6 4.5 4 0 0 4 4 4 1 KRI1-like family VASt PF16016.5 ORY15388.1 - 4.4e-27 95.4 0.0 9.1e-27 94.3 0.0 1.6 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain BAR_3 PF16746.5 ORY15388.1 - 4e-18 66.0 0.0 7.6e-18 65.1 0.0 1.4 1 0 0 1 1 1 1 BAR domain of APPL family PH PF00169.29 ORY15388.1 - 7e-11 42.6 0.2 2.7e-10 40.7 0.1 2.1 2 0 0 2 2 2 1 PH domain BAR PF03114.18 ORY15388.1 - 0.0008 19.1 0.2 0.0022 17.7 0.1 1.7 1 1 0 1 1 1 1 BAR domain Nitr_red_assoc PF09655.10 ORY15388.1 - 0.15 12.7 0.6 6.4 7.4 0.1 2.6 2 0 0 2 2 2 0 Conserved nitrate reductase-associated protein (Nitr_red_assoc) DUF2799 PF10973.8 ORY15389.1 - 0.0092 16.4 3.9 0.0092 16.4 3.9 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2799) IpaC_SipC PF09599.10 ORY15389.1 - 0.064 12.8 3.0 0.084 12.4 3.0 1.1 1 0 0 1 1 1 0 Salmonella-Shigella invasin protein C (IpaC_SipC) NACHT PF05729.12 ORY15390.1 - 9e-24 84.3 0.2 1.7e-23 83.3 0.2 1.5 1 0 0 1 1 1 1 NACHT domain HET PF06985.11 ORY15390.1 - 7.1e-10 39.4 13.0 2.4e-09 37.7 0.7 3.3 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) RNA_helicase PF00910.22 ORY15390.1 - 0.022 15.2 0.0 0.053 13.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase vATP-synt_AC39 PF01992.16 ORY15390.1 - 0.08 12.4 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 ATP synthase (C/AC39) subunit AAA_11 PF13086.6 ORY15390.1 - 0.1 12.4 0.1 0.26 11.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain DivIC PF04977.15 ORY15390.1 - 0.11 12.3 0.9 0.4 10.5 0.0 2.2 2 0 0 2 2 2 0 Septum formation initiator AAA_19 PF13245.6 ORY15390.1 - 0.16 12.3 0.0 0.34 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain WD40 PF00400.32 ORY15391.1 - 1.2e-68 225.3 15.4 2.2e-13 50.4 0.1 5.1 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY15391.1 - 1.1e-23 83.3 0.0 0.00053 20.2 0.0 5.0 1 1 4 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 ORY15391.1 - 5e-14 52.0 9.4 0.073 12.0 0.1 5.4 1 1 4 5 5 5 5 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 ORY15391.1 - 6.8e-09 34.9 1.3 0.62 8.6 0.0 4.0 1 1 3 4 4 4 4 Nucleoporin Nup120/160 DUF5643 PF18705.1 ORY15391.1 - 1.2e-07 31.7 0.0 9.4 6.2 0.0 5.0 5 0 0 5 5 5 2 Family of unknown function (DUF5643) PD40 PF07676.12 ORY15391.1 - 6.3e-06 26.0 2.0 46 4.1 0.0 5.4 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Frtz PF11768.8 ORY15391.1 - 7.7e-06 24.5 0.0 0.41 8.9 0.0 3.9 1 1 3 4 4 4 4 WD repeat-containing and planar cell polarity effector protein Fritz BLUF PF04940.12 ORY15391.1 - 2.2e-05 24.5 0.0 33 4.7 0.0 5.0 5 0 0 5 5 5 0 Sensors of blue-light using FAD TcfC PF16967.5 ORY15391.1 - 9.7e-05 21.8 0.0 9.8 5.8 0.0 3.5 4 0 0 4 4 4 3 E-set like domain CDtoxinA PF03498.14 ORY15391.1 - 0.00025 20.7 0.0 1.6 8.3 0.0 3.4 1 1 2 3 3 3 3 Cytolethal distending toxin A/C domain HARP PF07443.13 ORY15391.1 - 0.00026 20.5 0.0 13 5.5 0.0 3.4 3 0 0 3 3 3 0 HepA-related protein (HARP) Nbas_N PF15492.6 ORY15391.1 - 0.0015 18.0 3.0 15 4.8 0.0 4.4 1 1 4 5 5 5 0 Neuroblastoma-amplified sequence, N terminal WD40_like PF17005.5 ORY15391.1 - 0.0068 15.8 0.0 2.9 7.1 0.0 3.2 1 1 3 4 4 4 1 WD40-like domain Peptidase_M7 PF02031.16 ORY15391.1 - 0.016 15.3 3.0 15 5.7 0.1 3.6 1 1 3 4 4 4 0 Streptomyces extracellular neutral proteinase (M7) family DUF72 PF01904.18 ORY15393.1 - 0.082 13.0 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF72 Crystall_3 PF08964.10 ORY15394.1 - 9.5e-07 28.9 0.0 1.3e-06 28.5 0.0 1.1 1 0 0 1 1 1 1 Beta/Gamma crystallin Syncollin PF15138.6 ORY15394.1 - 0.01 16.0 2.8 0.018 15.2 2.8 1.5 1 1 0 1 1 1 0 Syncollin Crystall_3 PF08964.10 ORY15395.1 - 0.0012 18.9 0.0 0.0018 18.4 0.0 1.2 1 0 0 1 1 1 1 Beta/Gamma crystallin Fungal_trans_2 PF11951.8 ORY15398.1 - 0.0076 15.1 0.1 0.016 14.1 0.1 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Na_Ala_symp PF01235.17 ORY15398.1 - 0.12 11.7 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Sodium:alanine symporter family DUF3818 PF12825.7 ORY15400.1 - 2.3e-53 181.4 0.0 2.7e-33 115.4 0.1 2.8 1 1 1 2 2 2 2 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 ORY15400.1 - 4.4e-38 130.2 0.0 1e-37 129.0 0.0 1.7 1 0 0 1 1 1 1 PX-associated Metal_resist PF13801.6 ORY15400.1 - 0.024 14.8 0.0 0.089 13.0 0.0 2.0 1 0 0 1 1 1 0 Heavy-metal resistance DSBA PF01323.20 ORY15401.1 - 2e-25 89.7 0.0 2.2e-25 89.5 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain DUF4143 PF13635.6 ORY15401.1 - 0.091 12.9 0.0 0.19 11.9 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4143) But2 PF09792.9 ORY15404.1 - 2.4e-27 96.0 0.0 4e-27 95.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain DUF1075 PF06388.11 ORY15406.1 - 0.18 11.8 2.0 0.16 12.0 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1075) Birna_VP3 PF01767.16 ORY15409.1 - 0.01 15.9 1.8 0.014 15.5 1.8 1.3 1 0 0 1 1 1 0 Birnavirus VP3 protein UPF0688 PF15772.5 ORY15409.1 - 0.021 15.1 4.7 0.032 14.5 4.7 1.2 1 0 0 1 1 1 0 UPF0688 family zf-C2H2_jaz PF12171.8 ORY15409.1 - 0.055 13.8 0.4 0.2 12.0 0.1 2.1 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ORY15409.1 - 0.069 13.6 0.6 0.39 11.2 0.1 2.5 3 0 0 3 3 3 0 Zinc-finger of C2H2 type SNARE_assoc PF09335.11 ORY15410.1 - 1.7e-20 73.7 8.8 3.5e-19 69.5 8.9 2.3 2 0 0 2 2 2 1 SNARE associated Golgi protein SieB PF14163.6 ORY15410.1 - 0.0043 16.5 9.7 0.0051 16.3 1.0 3.1 2 1 2 4 4 4 1 Super-infection exclusion protein B YrhC PF14143.6 ORY15410.1 - 0.0048 16.9 0.3 0.013 15.5 0.3 1.8 1 0 0 1 1 1 1 YrhC-like protein DUF1772 PF08592.11 ORY15410.1 - 0.023 15.0 2.0 0.57 10.5 1.1 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF1772) Phage_Gp23 PF10669.9 ORY15410.1 - 0.024 15.0 1.1 0.055 13.8 1.1 1.5 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) SARAF PF06682.12 ORY15410.1 - 0.048 13.3 0.0 0.085 12.5 0.0 1.3 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis DUF2681 PF10883.8 ORY15410.1 - 0.11 12.9 1.8 0.18 12.2 0.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) Phage_holin_3_6 PF07332.11 ORY15410.1 - 0.13 12.4 14.0 0.14 12.2 0.7 2.9 2 1 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III DUF4131 PF13567.6 ORY15410.1 - 0.2 11.3 3.4 11 5.6 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) CbiM PF01891.16 ORY15410.1 - 2.5 7.9 16.2 0.031 14.1 3.9 2.7 2 1 0 2 2 2 0 Cobalt uptake substrate-specific transmembrane region adh_short PF00106.25 ORY15411.1 - 9.5e-35 119.8 0.1 1.4e-34 119.2 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY15411.1 - 4e-24 85.5 0.3 5.8e-24 84.9 0.3 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY15411.1 - 9.4e-11 41.9 0.4 1.9e-10 40.9 0.4 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 ORY15411.1 - 0.031 13.8 0.0 6.9 6.0 0.0 2.2 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 ORY15411.1 - 0.099 11.8 0.1 0.14 11.2 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein THF_DHG_CYH_C PF02882.19 ORY15411.1 - 0.14 11.4 0.1 0.33 10.3 0.0 1.6 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain bZIP_1 PF00170.21 ORY15412.1 - 0.82 9.8 4.2 1.7 8.8 4.2 1.4 1 0 0 1 1 1 0 bZIP transcription factor CTP_transf_like PF01467.26 ORY15413.1 - 0.0017 18.6 0.0 0.0051 17.0 0.0 1.9 1 1 0 1 1 1 1 Cytidylyltransferase-like AAA_27 PF13514.6 ORY15415.1 - 0.0038 16.9 0.6 0.12 11.9 0.1 2.5 1 1 2 3 3 3 2 AAA domain HS1_rep PF02218.15 ORY15415.1 - 0.0039 17.5 0.8 1.9 8.9 0.0 3.5 3 0 0 3 3 3 2 Repeat in HS1/Cortactin CpeS PF09367.10 ORY15415.1 - 0.061 13.2 0.1 0.12 12.3 0.0 1.3 1 1 0 1 1 1 0 CpeS-like protein Bac_export_3 PF01313.19 ORY15418.1 - 0.16 11.9 9.7 0.062 13.2 6.8 1.7 1 1 1 2 2 2 0 Bacterial export proteins, family 3 AAA PF00004.29 ORY15421.1 - 1.1e-38 132.6 0.0 7.2e-14 52.3 0.0 3.5 3 0 0 3 3 3 3 ATPase family associated with various cellular activities (AAA) AAA_lid_6 PF17866.1 ORY15421.1 - 3.3e-19 68.8 1.8 4.5e-10 39.6 0.0 3.8 3 0 0 3 3 3 3 AAA lid domain AAA_22 PF13401.6 ORY15421.1 - 1.8e-13 51.0 4.5 0.53 10.6 0.0 6.5 5 1 1 6 6 6 4 AAA domain AAA_30 PF13604.6 ORY15421.1 - 4.6e-13 49.3 0.1 0.00046 20.0 0.0 3.5 3 0 0 3 3 3 3 AAA domain AAA_5 PF07728.14 ORY15421.1 - 5.9e-11 42.5 0.1 0.021 14.8 0.0 4.2 3 1 0 3 3 3 3 AAA domain (dynein-related subfamily) AAA_11 PF13086.6 ORY15421.1 - 5.7e-09 36.1 1.1 0.0067 16.2 0.0 4.0 4 0 0 4 4 4 3 AAA domain AAA_33 PF13671.6 ORY15421.1 - 1.9e-08 34.6 0.7 0.076 13.2 0.0 3.7 3 0 0 3 3 3 2 AAA domain AAA_24 PF13479.6 ORY15421.1 - 8e-08 32.2 1.6 0.068 12.9 0.0 3.6 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.6 ORY15421.1 - 2.4e-07 31.3 0.4 0.7 10.3 0.0 4.2 3 0 0 3 3 3 2 AAA ATPase domain Mg_chelatase PF01078.21 ORY15421.1 - 4.9e-07 29.4 0.1 0.45 9.9 0.0 3.6 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 ORY15421.1 - 1.7e-06 28.5 1.1 0.67 10.3 0.0 4.0 3 1 1 4 4 4 1 AAA domain RNA_helicase PF00910.22 ORY15421.1 - 2.4e-06 27.9 0.2 2.5 8.5 0.0 3.7 3 0 0 3 3 3 2 RNA helicase RuvB_N PF05496.12 ORY15421.1 - 2.8e-06 27.2 0.1 0.12 12.1 0.0 3.9 3 1 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_17 PF13207.6 ORY15421.1 - 3e-06 27.7 3.0 0.18 12.2 0.0 3.8 3 0 0 3 3 3 2 AAA domain Viral_helicase1 PF01443.18 ORY15421.1 - 8.9e-06 25.6 0.7 0.4 10.4 0.0 3.6 4 0 0 4 4 4 1 Viral (Superfamily 1) RNA helicase IstB_IS21 PF01695.17 ORY15421.1 - 1e-05 25.3 0.2 0.28 10.9 0.0 3.5 3 0 0 3 3 3 2 IstB-like ATP binding protein AAA_18 PF13238.6 ORY15421.1 - 1.2e-05 25.8 1.5 0.66 10.5 0.1 4.0 3 0 0 3 3 3 1 AAA domain AAA_7 PF12775.7 ORY15421.1 - 8.1e-05 22.2 0.4 1.9 8.0 0.0 3.4 3 0 0 3 3 3 2 P-loop containing dynein motor region Zeta_toxin PF06414.12 ORY15421.1 - 8.1e-05 22.0 0.4 0.39 10.0 0.0 3.3 3 0 0 3 3 3 2 Zeta toxin AAA_14 PF13173.6 ORY15421.1 - 0.00013 22.0 0.0 0.46 10.5 0.0 3.6 3 0 0 3 3 3 1 AAA domain AAA_28 PF13521.6 ORY15421.1 - 0.0002 21.6 9.6 0.49 10.6 0.1 3.9 4 0 0 4 4 3 2 AAA domain Torsin PF06309.11 ORY15421.1 - 0.00071 19.7 0.0 9.3 6.4 0.0 3.6 3 0 0 3 3 3 0 Torsin KTI12 PF08433.10 ORY15421.1 - 0.001 18.6 2.6 0.7 9.3 0.0 4.0 5 0 0 5 5 4 1 Chromatin associated protein KTI12 Sigma54_activat PF00158.26 ORY15421.1 - 0.0014 18.4 0.8 25 4.5 0.0 4.6 4 1 0 4 4 4 0 Sigma-54 interaction domain AAA_25 PF13481.6 ORY15421.1 - 0.0022 17.6 1.2 14 5.2 0.0 4.4 4 0 0 4 4 4 0 AAA domain TniB PF05621.11 ORY15421.1 - 0.0023 17.4 0.3 1.3 8.4 0.0 4.2 4 1 1 5 5 4 1 Bacterial TniB protein TsaE PF02367.17 ORY15421.1 - 0.0049 16.9 1.1 31 4.6 0.0 4.3 4 0 0 4 4 4 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF3987 PF13148.6 ORY15421.1 - 0.0054 15.8 0.0 0.27 10.2 0.0 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF3987) SRP54 PF00448.22 ORY15421.1 - 0.0072 16.0 2.1 1 9.0 0.0 3.5 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain AAA_29 PF13555.6 ORY15421.1 - 0.012 15.4 2.8 2.1 8.1 0.0 3.9 4 0 0 4 4 4 0 P-loop containing region of AAA domain ABC_tran PF00005.27 ORY15421.1 - 0.016 15.7 1.0 16 6.0 0.1 3.9 3 1 1 4 4 4 0 ABC transporter NTPase_1 PF03266.15 ORY15421.1 - 0.021 14.7 2.2 13 5.7 0.0 3.4 3 0 0 3 3 3 0 NTPase ATPase PF06745.13 ORY15421.1 - 0.022 14.1 2.2 6.8 6.0 0.1 3.3 3 0 0 3 3 3 0 KaiC ADK PF00406.22 ORY15421.1 - 0.023 14.8 0.9 18 5.4 0.0 3.6 3 0 0 3 3 3 0 Adenylate kinase CbiA PF01656.23 ORY15421.1 - 0.054 13.6 0.7 24 5.0 0.1 3.5 3 0 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_10 PF12846.7 ORY15421.1 - 0.083 11.8 0.2 2.2 7.1 0.0 2.8 3 0 0 3 3 3 0 AAA-like domain SesA PF17107.5 ORY15421.1 - 0.12 12.6 0.2 0.54 10.5 0.2 2.2 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases NACHT PF05729.12 ORY15421.1 - 0.14 12.0 3.5 25 4.7 0.2 3.7 3 0 0 3 3 3 0 NACHT domain DUF2075 PF09848.9 ORY15421.1 - 2.5 7.2 6.4 38 3.3 0.1 4.2 4 1 1 5 5 5 0 Uncharacterized conserved protein (DUF2075) ATP_bind_1 PF03029.17 ORY15421.1 - 2.7 7.7 3.7 57 3.4 0.0 3.2 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein DUF5572 PF17733.1 ORY15422.1 - 2.9e-23 81.4 1.3 5.5e-23 80.5 1.3 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF5572) LSM14 PF12701.7 ORY15423.1 - 1.4e-29 102.0 0.1 2.2e-29 101.4 0.1 1.3 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.10 ORY15423.1 - 4.6e-19 69.2 1.6 1.9e-18 67.2 1.6 2.1 1 0 0 1 1 1 1 FDF domain SM-ATX PF14438.6 ORY15423.1 - 8.5e-07 29.0 0.0 1.4e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM PF01423.22 ORY15423.1 - 0.18 11.5 0.0 0.29 10.9 0.0 1.3 1 0 0 1 1 1 0 LSM domain DUF2011 PF09428.10 ORY15425.1 - 1.2e-23 83.1 1.8 4.5e-23 81.3 0.0 2.3 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF2011) Ribosomal_L37 PF08561.10 ORY15425.1 - 1.2 9.6 14.6 1.1 9.8 13.0 1.6 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L37 YtxH PF12732.7 ORY15425.1 - 6.4 7.4 11.9 13 6.4 11.9 1.6 1 0 0 1 1 1 0 YtxH-like protein DUF3604 PF12228.8 ORY15428.1 - 0.24 9.8 0.0 0.27 9.6 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3604) Ank_2 PF12796.7 ORY15430.1 - 3.9e-37 126.7 0.0 2.3e-13 50.5 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ORY15430.1 - 1.6e-35 120.7 4.3 3.2e-10 40.0 0.1 5.0 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 ORY15430.1 - 2.3e-31 107.8 0.7 5.4e-09 36.4 0.0 4.9 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 ORY15430.1 - 3.5e-23 81.0 0.0 0.00012 22.3 0.0 5.1 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 ORY15430.1 - 6.2e-23 78.4 0.0 1.2e-05 25.3 0.0 5.1 5 0 0 5 5 5 5 Ankyrin repeat Hairy_orange PF07527.13 ORY15430.1 - 5.1e-05 23.4 0.1 1.2 9.4 0.0 3.5 3 0 0 3 3 3 2 Hairy Orange NapD PF03927.13 ORY15430.1 - 0.005 16.9 0.0 7.9 6.6 0.0 3.3 2 1 2 4 4 4 2 NapD protein BRCA-2_helical PF09169.10 ORY15430.1 - 0.075 12.7 0.0 2.3 7.8 0.0 2.2 1 1 1 2 2 2 0 BRCA2, helical PPR_3 PF13812.6 ORY15430.1 - 0.087 12.9 0.0 10 6.3 0.0 2.6 3 0 0 3 3 3 0 Pentatricopeptide repeat domain AAA_lid_2 PF17863.1 ORY15430.1 - 0.15 11.9 0.1 22 5.0 0.0 2.4 2 0 0 2 2 2 0 AAA lid domain Amidohydro_1 PF01979.20 ORY15432.1 - 1.3e-23 83.9 0.0 4e-23 82.3 0.0 1.8 2 1 0 2 2 2 1 Amidohydrolase family Amidohydro_3 PF07969.11 ORY15432.1 - 1.9e-14 54.0 0.1 7.6e-07 29.0 0.0 2.8 3 0 0 3 3 3 2 Amidohydrolase family Urease_alpha PF00449.20 ORY15432.1 - 0.023 15.0 0.9 0.046 14.0 0.9 1.5 1 0 0 1 1 1 0 Urease alpha-subunit, N-terminal domain Peptidase_M20 PF01546.28 ORY15433.1 - 3.1e-31 108.7 0.0 5.8e-31 107.8 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 ORY15433.1 - 2.5e-07 30.6 0.0 6e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 ORY15433.1 - 0.0016 18.2 0.0 0.0026 17.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 COesterase PF00135.28 ORY15434.1 - 6.8e-62 210.0 0.0 1e-61 209.4 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 ORY15434.1 - 4e-10 39.9 0.0 8.5e-10 38.8 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 ORY15434.1 - 0.0012 17.8 0.1 0.0034 16.3 0.1 1.6 1 1 0 1 1 1 1 Steryl acetyl hydrolase FAD_binding_3 PF01494.19 ORY15435.1 - 8.4e-63 212.7 0.0 1.1e-62 212.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 ORY15435.1 - 2.5e-06 27.6 0.0 1.1e-05 25.5 0.0 2.1 1 1 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain DAO PF01266.24 ORY15435.1 - 3.6e-06 26.8 0.0 6.1e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 ORY15435.1 - 7.1e-05 21.8 0.0 0.00013 21.0 0.0 1.4 1 0 0 1 1 1 1 Tryptophan halogenase NAD_binding_8 PF13450.6 ORY15435.1 - 0.00028 21.1 0.0 0.00095 19.4 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 ORY15435.1 - 0.002 18.1 0.1 0.0063 16.5 0.0 1.8 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.17 ORY15435.1 - 0.0022 17.3 0.0 0.0034 16.7 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 ORY15435.1 - 0.0039 16.5 0.0 0.0094 15.2 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ORY15435.1 - 0.032 12.9 0.0 0.066 11.9 0.0 1.5 2 0 0 2 2 2 0 HI0933-like protein Glu_dehyd_C PF16912.5 ORY15435.1 - 0.097 12.1 0.0 3.9 6.9 0.0 2.3 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus TrkA_N PF02254.18 ORY15435.1 - 0.17 12.2 0.0 0.34 11.2 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Cys_Met_Meta_PP PF01053.20 ORY15436.1 - 3.3e-138 460.4 0.0 3.9e-138 460.2 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 ORY15436.1 - 7.9e-08 31.6 0.6 1.9e-07 30.4 0.6 1.7 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 ORY15436.1 - 4.5e-06 26.2 1.0 8.9e-06 25.2 1.0 1.4 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Met_gamma_lyase PF06838.11 ORY15436.1 - 1.3e-05 23.9 0.1 1.9e-05 23.3 0.1 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase Beta_elim_lyase PF01212.21 ORY15436.1 - 9.2e-05 21.9 0.3 0.00023 20.6 0.3 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 ORY15436.1 - 0.0027 17.0 0.1 0.0038 16.5 0.1 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II IMPDH PF00478.25 ORY15436.1 - 0.006 15.6 0.5 0.006 15.6 0.5 1.5 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain GDC-P PF02347.16 ORY15436.1 - 0.023 13.5 0.0 0.033 13.0 0.0 1.1 1 0 0 1 1 1 0 Glycine cleavage system P-protein Asparaginase_C PF17763.1 ORY15436.1 - 0.13 12.5 0.0 0.27 11.4 0.0 1.5 1 0 0 1 1 1 0 Glutaminase/Asparaginase C-terminal domain SepSecS PF05889.13 ORY15436.1 - 0.18 10.5 0.0 0.27 9.9 0.0 1.1 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Abhydrolase_1 PF00561.20 ORY15437.1 - 3.9e-34 118.5 0.0 4.9e-34 118.1 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORY15437.1 - 0.0012 19.5 1.2 0.0016 19.0 1.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 ORY15437.1 - 0.03 14.4 0.0 0.063 13.4 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein CN_hydrolase PF00795.22 ORY15438.1 - 3.3e-56 190.5 0.0 3.8e-56 190.3 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase AA_kinase PF00696.28 ORY15439.1 - 4e-34 118.3 0.1 7.7e-34 117.4 0.1 1.5 1 0 0 1 1 1 1 Amino acid kinase family ACT PF01842.25 ORY15439.1 - 1.1e-08 34.7 4.2 5e-06 26.2 0.2 3.1 3 0 0 3 3 3 2 ACT domain ACT_7 PF13840.6 ORY15439.1 - 2.2e-08 33.8 1.7 3.2e-08 33.2 0.6 1.9 2 0 0 2 2 2 1 ACT domain Peptidase_M6 PF05547.11 ORY15440.1 - 1.3e-25 89.9 7.7 1.4e-23 83.2 2.8 2.4 1 1 1 2 2 2 2 Immune inhibitor A peptidase M6 RicinB_lectin_2 PF14200.6 ORY15440.1 - 8.4e-08 32.8 4.7 0.0004 21.1 0.2 4.0 3 1 0 3 3 3 2 Ricin-type beta-trefoil lectin domain-like FAD_binding_3 PF01494.19 ORY15441.1 - 3.3e-17 62.8 0.8 5.7e-12 45.5 0.0 2.7 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.24 ORY15441.1 - 0.0018 17.9 0.3 0.0093 15.6 0.3 1.9 1 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ORY15441.1 - 0.0055 16.9 0.0 0.014 15.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ORY15441.1 - 0.0091 15.3 0.0 0.081 12.1 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORY15441.1 - 0.1 13.2 0.0 2 9.0 0.0 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 ORY15441.1 - 0.13 11.3 0.0 1.7 7.6 0.0 2.1 1 1 0 1 1 1 0 Lycopene cyclase protein ABC_tran PF00005.27 ORY15442.1 - 1.9e-46 158.0 0.0 8.8e-24 84.6 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 ORY15442.1 - 1.1e-22 80.7 38.7 4.6e-12 45.7 19.5 2.3 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.6 ORY15442.1 - 1.1e-20 74.7 0.0 8.2e-05 22.6 0.0 4.3 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ORY15442.1 - 1.9e-09 37.3 5.6 0.003 17.0 0.0 4.6 5 0 0 5 5 5 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 ORY15442.1 - 2.5e-09 37.9 1.0 0.0022 18.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 ORY15442.1 - 6.5e-08 32.7 1.2 0.0072 16.3 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 ORY15442.1 - 2.7e-07 30.2 0.2 0.012 15.4 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 ORY15442.1 - 1.2e-05 25.8 0.2 0.09 13.2 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain DUF4162 PF13732.6 ORY15442.1 - 2.4e-05 25.0 0.0 0.0023 18.6 0.0 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4162) AAA_15 PF13175.6 ORY15442.1 - 0.00032 20.5 0.0 2.2 7.9 0.3 3.4 3 0 0 3 3 3 1 AAA ATPase domain AAA PF00004.29 ORY15442.1 - 0.00039 20.9 0.1 2 8.8 0.3 3.0 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 ORY15442.1 - 0.00047 20.5 0.4 0.44 10.8 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_27 PF13514.6 ORY15442.1 - 0.00056 19.6 0.2 0.37 10.4 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 ORY15442.1 - 0.0011 18.8 0.3 1.9 8.2 0.1 3.0 2 1 1 3 3 3 2 AAA domain Rad17 PF03215.15 ORY15442.1 - 0.0028 17.6 0.2 0.51 10.2 0.1 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain RNA_helicase PF00910.22 ORY15442.1 - 0.0055 17.1 0.0 0.48 10.8 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_PrkA PF08298.11 ORY15442.1 - 0.006 15.5 0.0 2.8 6.7 0.0 2.2 2 0 0 2 2 2 2 PrkA AAA domain Mg_chelatase PF01078.21 ORY15442.1 - 0.0092 15.4 1.0 15 4.9 0.0 3.3 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 ORY15442.1 - 0.018 14.8 0.2 50 3.6 0.1 3.9 4 0 0 4 4 4 0 IstB-like ATP binding protein SbcCD_C PF13558.6 ORY15442.1 - 0.021 15.1 0.1 11 6.3 0.1 3.4 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Zeta_toxin PF06414.12 ORY15442.1 - 0.049 12.9 0.2 7.5 5.8 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin TsaE PF02367.17 ORY15442.1 - 0.067 13.2 0.2 17 5.5 0.1 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SRP54 PF00448.22 ORY15442.1 - 0.1 12.2 0.3 4.3 6.9 0.1 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_24 PF13479.6 ORY15442.1 - 0.1 12.3 1.7 13 5.4 0.1 2.8 3 0 0 3 3 2 0 AAA domain AAA_19 PF13245.6 ORY15442.1 - 0.12 12.7 1.1 1.8 8.9 0.1 2.4 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 ORY15442.1 - 0.17 12.0 1.6 14 5.8 0.2 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase T2SSE PF00437.20 ORY15442.1 - 0.39 9.7 2.6 0.87 8.6 0.3 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein ABC2_membrane_2 PF12679.7 ORY15442.1 - 0.68 9.2 34.1 0.8 8.9 9.8 3.0 2 1 1 3 3 3 0 ABC-2 family transporter protein T2SSppdC PF12528.8 ORY15443.1 - 0.099 13.4 0.1 0.22 12.3 0.0 1.6 2 0 0 2 2 2 0 Type II secretion prepilin peptidase dependent protein C Comm PF15957.5 ORY15444.1 - 0.11 12.8 0.0 0.26 11.6 0.0 1.6 1 0 0 1 1 1 0 Commissureless Methyltransf_4 PF02390.17 ORY15445.1 - 0.22 11.0 0.0 0.29 10.6 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Peptidase_M28 PF04389.17 ORY15446.1 - 4e-33 114.8 0.0 7.6e-33 113.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 ORY15446.1 - 0.0073 16.0 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 DUF641 PF04859.12 ORY15447.1 - 0.0053 17.1 44.3 0.086 13.2 4.8 5.2 2 2 2 4 4 4 2 Plant protein of unknown function (DUF641) YgbB PF02542.16 ORY15447.1 - 0.086 13.1 0.6 0.25 11.6 0.6 1.7 1 0 0 1 1 1 0 YgbB family Fib_alpha PF08702.10 ORY15447.1 - 0.18 12.0 33.1 0.02 15.1 5.2 4.7 2 2 2 4 4 4 0 Fibrinogen alpha/beta chain family CEP63 PF17045.5 ORY15447.1 - 0.41 10.5 53.1 0.041 13.8 15.4 2.5 2 0 0 2 2 2 0 Centrosomal protein of 63 kDa SpoOE-like PF09388.10 ORY15447.1 - 0.99 9.4 5.7 16 5.5 0.1 3.2 3 0 0 3 3 3 0 Spo0E like sporulation regulatory protein HMMR_N PF15905.5 ORY15447.1 - 8.2 5.8 59.4 2.6 7.4 20.4 3.8 2 2 1 3 3 3 0 Hyaluronan mediated motility receptor N-terminal Cyclase PF04199.13 ORY15449.1 - 9.7e-13 48.5 0.0 2.5e-12 47.2 0.0 1.7 1 1 0 1 1 1 1 Putative cyclase MttA_Hcf106 PF02416.16 ORY15450.1 - 0.15 11.5 0.2 0.31 10.4 0.2 1.5 1 0 0 1 1 1 0 mttA/Hcf106 family p450 PF00067.22 ORY15451.1 - 5.2e-50 170.5 0.0 8.9e-49 166.5 0.0 2.1 1 1 0 1 1 1 1 Cytochrome P450 Acyl-CoA_dh_1 PF00441.24 ORY15453.1 - 1.6e-36 125.8 0.1 2.2e-36 125.3 0.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 ORY15453.1 - 2.7e-19 69.2 0.2 6.8e-19 67.9 0.1 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 ORY15453.1 - 2.8e-10 40.6 0.0 4.6e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 ORY15453.1 - 1.6e-09 38.4 0.0 8.9e-09 36.0 0.0 2.3 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain HpaB_N PF11794.8 ORY15453.1 - 0.00033 20.4 0.0 0.00054 19.7 0.0 1.3 1 0 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal DEAD_2 PF06733.15 ORY15453.1 - 0.1 12.2 0.1 0.17 11.5 0.1 1.2 1 0 0 1 1 1 0 DEAD_2 PH_BEACH PF14844.6 ORY15453.1 - 0.14 12.3 0.0 0.88 9.7 0.0 2.1 2 0 0 2 2 2 0 PH domain associated with Beige/BEACH 3Beta_HSD PF01073.19 ORY15454.1 - 1.2e-37 129.4 0.0 1.6e-37 129.0 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 ORY15454.1 - 7.7e-21 74.7 0.0 1.1e-20 74.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ORY15454.1 - 1.6e-13 50.8 0.0 5.5e-12 45.7 0.0 2.8 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 ORY15454.1 - 1.5e-07 31.5 0.0 2.2e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 ORY15454.1 - 1.4e-06 27.7 0.1 0.0036 16.5 0.0 2.1 1 1 1 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.15 ORY15454.1 - 1.4e-05 24.4 0.0 4.4e-05 22.8 0.0 1.8 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 ORY15454.1 - 0.00041 19.5 0.0 0.00062 19.0 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain KR PF08659.10 ORY15454.1 - 0.014 15.4 0.3 0.23 11.3 0.0 2.3 2 1 0 2 2 2 0 KR domain Sacchrp_dh_NADP PF03435.18 ORY15454.1 - 0.051 13.8 0.0 0.088 13.1 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain adh_short PF00106.25 ORY15454.1 - 0.16 11.4 0.0 0.34 10.4 0.0 1.5 1 0 0 1 1 1 0 short chain dehydrogenase Mrx7 PF10906.8 ORY15454.1 - 0.25 11.6 0.8 0.52 10.6 0.0 1.9 2 0 0 2 2 2 0 MIOREX complex component 7 Cohesin_load PF10345.9 ORY15456.1 - 2.7e-131 438.9 0.2 3.3e-131 438.7 0.2 1.1 1 0 0 1 1 1 1 Cohesin loading factor Abhydrolase_1 PF00561.20 ORY15457.1 - 8.1e-16 58.4 0.0 6.8e-14 52.1 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ORY15457.1 - 1.1e-07 31.3 0.0 6e-07 29.0 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ORY15457.1 - 0.00029 21.5 0.0 0.00046 20.9 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Cutinase PF01083.22 ORY15457.1 - 0.09 12.7 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Cutinase PIN_12 PF16289.5 ORY15458.1 - 0.02 15.4 1.3 0.033 14.7 1.3 1.4 1 0 0 1 1 1 0 PIN domain UPF0220 PF05255.11 ORY15459.1 - 9.8e-73 243.2 1.3 1.2e-72 242.9 1.3 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) Vps55 PF04133.14 ORY15460.1 - 9.7e-42 141.6 7.9 1.1e-41 141.5 7.9 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 DUF4349 PF14257.6 ORY15460.1 - 0.18 11.2 0.1 0.18 11.2 0.1 1.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4349) DUF2614 PF11023.8 ORY15460.1 - 9.7 6.3 6.8 1.1 9.3 0.7 2.0 2 0 0 2 2 2 0 Zinc-ribbon containing domain Proteasome PF00227.26 ORY15461.1 - 2.9e-48 163.9 0.1 3.9e-48 163.5 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 ORY15461.1 - 1.1e-10 41.0 1.1 1.2e-10 40.8 0.2 1.6 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DUF1403 PF07183.11 ORY15461.1 - 0.031 13.8 0.0 0.045 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1403) Flg_hook PF02120.16 ORY15461.1 - 0.068 13.1 0.3 4.4 7.3 0.0 2.8 3 0 0 3 3 3 0 Flagellar hook-length control protein FliK ATP-synt_Eps PF04627.13 ORY15462.1 - 5.6e-24 83.9 2.4 8.1e-24 83.4 2.4 1.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain DUF2117 PF09890.9 ORY15462.1 - 0.07 12.6 0.0 0.073 12.5 0.0 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2117) Mak10 PF04112.13 ORY15463.1 - 3.5e-63 212.1 0.0 5e-63 211.6 0.0 1.2 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase CBFD_NFYB_HMF PF00808.23 ORY15464.1 - 7.6e-06 26.1 0.0 9.6e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-W PF15510.6 ORY15464.1 - 0.0013 18.9 0.1 0.0015 18.7 0.1 1.2 1 0 0 1 1 1 1 CENP-W protein TAFII28 PF04719.14 ORY15464.1 - 0.0091 16.1 0.0 0.011 15.8 0.0 1.1 1 0 0 1 1 1 1 hTAFII28-like protein conserved region Peptidase_M16 PF00675.20 ORY15465.1 - 4.1e-12 46.3 0.0 7.4e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 ORY15465.1 - 5.4e-10 39.6 0.0 1.2e-09 38.5 0.0 1.6 2 0 0 2 2 2 1 Peptidase M16 inactive domain RNA_pol_Rpc82 PF05645.13 ORY15466.1 - 3.3e-35 122.1 0.0 4.4e-32 111.8 0.0 3.6 3 1 0 3 3 3 2 RNA polymerase III subunit RPC82 HTH_9 PF08221.11 ORY15466.1 - 1.4e-15 57.2 0.7 1.5e-14 53.9 0.4 2.5 3 0 0 3 3 3 1 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.17 ORY15466.1 - 0.00018 21.3 0.9 0.58 10.0 0.2 3.3 2 1 1 3 3 3 2 TFIIE alpha subunit DUF3638 PF12340.8 ORY15467.1 - 2.8e-89 298.3 0.0 4.8e-89 297.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.8 ORY15467.1 - 1.2e-14 53.4 0.3 2.6e-14 52.3 0.3 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) MHC_I_3 PF16497.5 ORY15467.1 - 0.04 13.4 0.1 0.096 12.2 0.1 1.6 1 0 0 1 1 1 0 MHC-I family domain Mycobact_memb PF05423.13 ORY15467.1 - 0.16 11.9 0.0 0.33 10.9 0.0 1.5 1 0 0 1 1 1 0 Mycobacterium membrane protein Pec_lyase_C PF00544.19 ORY15468.1 - 2.9e-17 62.9 7.1 8.4e-16 58.2 7.1 2.2 1 1 0 1 1 1 1 Pectate lyase Ank_2 PF12796.7 ORY15471.1 - 1.1e-10 41.9 0.1 3.3e-05 24.4 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY15471.1 - 1.8e-09 38.0 0.1 0.00085 19.8 0.0 4.7 3 2 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY15471.1 - 5.7e-05 23.2 0.1 0.89 10.3 0.0 4.8 5 1 1 6 6 6 2 Ankyrin repeat Ank_5 PF13857.6 ORY15471.1 - 6.4e-05 23.1 0.3 0.18 12.2 0.0 4.6 3 2 2 5 5 5 1 Ankyrin repeats (many copies) Ank PF00023.30 ORY15471.1 - 0.00058 20.2 0.4 1.7 9.2 0.0 4.3 5 0 0 5 5 5 1 Ankyrin repeat SUI1 PF01253.22 ORY15472.1 - 3.2e-21 75.7 0.0 5.9e-21 74.8 0.0 1.5 1 0 0 1 1 1 1 Translation initiation factor SUI1 Pre-PUA PF17832.1 ORY15472.1 - 8.4e-07 29.6 0.2 2.8e-05 24.7 0.2 2.6 1 1 0 1 1 1 1 Pre-PUA-like domain Kin17_mid PF10357.9 ORY15472.1 - 0.013 15.4 0.0 0.028 14.3 0.0 1.4 1 0 0 1 1 1 0 Domain of Kin17 curved DNA-binding protein SWIB PF02201.18 ORY15472.1 - 0.16 11.9 0.0 0.38 10.7 0.0 1.6 1 0 0 1 1 1 0 SWIB/MDM2 domain 4HBT_2 PF13279.6 ORY15473.1 - 4.6e-05 23.9 0.0 6.7e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily K_oxygenase PF13434.6 ORY15474.1 - 0.018 14.2 0.0 0.033 13.3 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) SARS_lipid_bind PF09399.10 ORY15476.1 - 0.016 15.3 0.0 1.1 9.5 0.0 2.5 2 0 0 2 2 2 0 SARS lipid binding protein PARP PF00644.20 ORY15477.1 - 0.009 15.6 0.0 0.009 15.6 0.0 1.2 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain A2M PF00207.22 ORY15478.1 - 0.12 12.2 0.0 0.2 11.5 0.0 1.4 1 1 0 1 1 1 0 Alpha-2-macroglobulin family Bac_rhodopsin PF01036.18 ORY15480.1 - 0.12 12.0 2.4 0.067 12.8 0.5 1.6 2 0 0 2 2 2 0 Bacteriorhodopsin-like protein DUF1100 PF06500.11 ORY15480.1 - 0.12 11.1 0.0 0.16 10.7 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) DUF998 PF06197.13 ORY15480.1 - 0.26 10.9 4.6 0.092 12.3 1.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF998) TMEM154 PF15102.6 ORY15482.1 - 0.099 12.5 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 TMEM154 protein family DUF2207 PF09972.9 ORY15482.1 - 0.2 10.4 0.0 0.24 10.1 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) SKG6 PF08693.10 ORY15482.1 - 0.37 10.2 4.7 0.62 9.5 4.7 1.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Pectate_lyase_3 PF12708.7 ORY15484.1 - 3.9e-79 265.4 14.5 3.4e-68 229.7 8.0 2.7 2 0 0 2 2 2 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 ORY15484.1 - 0.064 13.0 3.8 0.14 11.9 0.3 3.0 3 0 0 3 3 3 0 N terminal extension of bacteriophage endosialidase adh_short PF00106.25 ORY15485.1 - 2.8e-31 108.5 0.1 3.7e-31 108.1 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY15485.1 - 5.4e-25 88.3 0.1 6.9e-25 88.0 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY15485.1 - 9.5e-08 32.2 0.2 1.2e-07 31.8 0.2 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 ORY15485.1 - 1.7e-05 24.8 0.2 3.1e-05 23.9 0.2 1.4 1 1 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 ORY15485.1 - 0.0014 17.7 0.2 0.0024 16.9 0.2 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 ORY15485.1 - 0.0016 18.0 0.1 0.0031 17.0 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 ORY15485.1 - 0.0043 16.2 0.2 0.045 12.9 0.2 2.1 1 1 0 1 1 1 1 Male sterility protein Ras PF00071.22 ORY15487.1 - 2.5e-48 163.8 0.2 4.5e-46 156.4 0.2 2.1 1 1 0 1 1 1 1 Ras family Roc PF08477.13 ORY15487.1 - 1e-28 100.0 0.0 3.5e-18 66.0 0.0 2.2 1 1 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY15487.1 - 2.4e-11 43.4 0.0 2.5e-10 40.1 0.0 1.9 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 ORY15487.1 - 1.1e-07 31.6 0.0 2.6e-07 30.4 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 ORY15487.1 - 6.2e-06 26.3 0.1 9.9e-05 22.4 0.0 2.6 1 1 1 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 ORY15487.1 - 1e-05 25.0 0.0 1.7e-05 24.3 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 ORY15487.1 - 0.011 15.6 0.8 0.91 9.4 0.1 2.3 1 1 0 2 2 2 0 RsgA GTPase PduV-EutP PF10662.9 ORY15487.1 - 0.063 13.0 0.1 2 8.1 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation PAF-AH_p_II PF03403.13 ORY15487.1 - 0.072 11.6 0.2 0.1 11.1 0.2 1.1 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II ABC_tran PF00005.27 ORY15487.1 - 0.1 13.1 0.7 0.82 10.2 0.7 2.2 1 1 0 1 1 1 0 ABC transporter HHV6-IE PF03753.13 ORY15488.1 - 0.033 11.7 0.1 0.041 11.3 0.1 1.0 1 0 0 1 1 1 0 Human herpesvirus 6 immediate early protein Choline_transpo PF04515.12 ORY15489.1 - 7.2e-24 84.6 16.9 7.2e-24 84.6 16.9 2.5 2 1 0 2 2 2 1 Plasma-membrane choline transporter SNF2_N PF00176.23 ORY15490.1 - 9.1e-10 37.8 0.1 2.3e-09 36.5 0.1 1.8 1 1 0 1 1 1 1 SNF2 family N-terminal domain Golgin_A5 PF09787.9 ORY15490.1 - 0.094 12.2 7.5 0.11 11.9 7.5 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 adh_short PF00106.25 ORY15491.1 - 1.4e-22 80.1 0.2 7.2e-19 68.0 0.2 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 ORY15491.1 - 1.3e-15 57.6 0.1 1e-13 51.4 0.1 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY15491.1 - 2.2e-05 24.4 0.1 5.6e-05 23.1 0.0 1.7 1 1 1 2 2 2 1 KR domain Epimerase PF01370.21 ORY15491.1 - 0.00025 20.6 0.0 0.00046 19.7 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ORY15491.1 - 0.022 14.2 0.1 0.045 13.1 0.0 1.5 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase GCP_N_terminal PF17681.1 ORY15493.1 - 2.8e-63 214.4 0.1 8.1e-63 212.9 0.0 1.7 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 ORY15493.1 - 9.9e-61 205.9 1.2 1.1e-60 205.7 0.1 1.7 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal NARP1 PF12569.8 ORY15493.1 - 0.37 9.6 1.8 2 7.2 0.0 2.1 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 F-box-like PF12937.7 ORY15494.1 - 1.4e-05 24.8 0.3 4.1e-05 23.4 0.3 1.8 1 0 0 1 1 1 1 F-box-like Proteasome PF00227.26 ORY15495.1 - 8.1e-56 188.5 0.0 1e-55 188.2 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 ORY15495.1 - 1.8e-12 46.7 0.0 3.6e-12 45.7 0.0 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature QCR10 PF09796.9 ORY15496.1 - 1.4e-30 105.1 0.6 1.9e-30 104.7 0.6 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) MFS_1 PF07690.16 ORY15497.1 - 3.4e-34 118.3 38.0 5.5e-24 84.7 12.7 2.7 2 1 0 2 2 2 2 Major Facilitator Superfamily Strabismus PF06638.11 ORY15497.1 - 0.055 12.1 0.0 0.1 11.2 0.0 1.4 2 0 0 2 2 2 0 Strabismus protein DUF4179 PF13786.6 ORY15497.1 - 9 6.9 6.5 2.7 8.5 0.2 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4179) Kelch_5 PF13854.6 ORY15499.1 - 1.6e-18 66.3 2.3 2e-11 43.6 0.1 4.1 3 0 0 3 3 3 3 Kelch motif Kelch_4 PF13418.6 ORY15499.1 - 3.6e-07 30.1 4.0 0.34 10.9 0.0 5.6 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_6 PF13964.6 ORY15499.1 - 4.1e-05 23.7 2.6 1.7 9.1 0.0 4.5 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.15 ORY15499.1 - 0.25 11.4 3.6 33 4.7 0.0 4.4 4 1 1 5 5 5 0 Kelch motif Glyco_hydro_17 PF00332.18 ORY15500.1 - 3e-07 30.3 1.7 4.5e-07 29.8 1.7 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 Esterase_phd PF10503.9 ORY15502.1 - 0.00053 19.5 0.0 0.0032 17.0 0.0 1.9 1 1 0 1 1 1 1 Esterase PHB depolymerase Abhydrolase_2 PF02230.16 ORY15502.1 - 0.00075 19.4 0.0 0.0026 17.6 0.0 1.8 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 ORY15502.1 - 0.019 14.4 0.1 0.069 12.6 0.1 1.8 1 1 0 1 1 1 0 Prolyl oligopeptidase family AXE1 PF05448.12 ORY15502.1 - 0.022 13.4 0.0 0.11 11.1 0.0 1.8 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) FSH1 PF03959.13 ORY15502.1 - 0.062 12.9 0.0 0.56 9.8 0.0 2.0 2 0 0 2 2 2 0 Serine hydrolase (FSH1) gag-asp_proteas PF13975.6 ORY15535.1 - 0.012 16.1 0.0 0.025 15.1 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease SBBP PF06739.11 ORY15537.1 - 0.0018 18.2 0.1 0.72 9.9 0.0 3.2 3 0 0 3 3 3 2 Beta-propeller repeat SGL PF08450.12 ORY15537.1 - 0.0051 16.4 0.2 0.42 10.2 0.0 2.8 2 1 0 2 2 2 2 SMP-30/Gluconolactonase/LRE-like region GSDH PF07995.11 ORY15537.1 - 0.34 10.2 4.9 2.4 7.4 3.0 3.1 3 2 0 3 3 3 0 Glucose / Sorbosone dehydrogenase SLAC1 PF03595.17 ORY15538.1 - 8.6e-85 284.8 41.3 9.7e-85 284.7 41.3 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel MurJ PF03023.14 ORY15538.1 - 1.6e-05 23.7 0.6 1.6e-05 23.7 0.6 1.8 2 0 0 2 2 2 1 Lipid II flippase MurJ DEAD PF00270.29 ORY15539.1 - 1.5e-47 161.6 0.0 5.1e-47 159.9 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY15539.1 - 7.4e-28 97.1 0.0 1.3e-26 93.1 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY15539.1 - 6.8e-06 26.2 0.0 1.9e-05 24.7 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 ORY15539.1 - 0.011 15.1 0.0 0.011 15.1 0.0 3.0 3 0 0 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit NUC194 PF08163.12 ORY15539.1 - 0.046 12.6 0.0 0.092 11.7 0.0 1.4 1 0 0 1 1 1 0 NUC194 domain BOP1NT PF08145.12 ORY15540.1 - 2.2e-104 349.0 7.9 3.3e-104 348.4 7.9 1.3 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.32 ORY15540.1 - 1.3e-21 76.5 1.1 1.4e-07 32.0 0.1 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY15540.1 - 5.6e-07 29.8 0.1 0.0037 17.5 0.0 4.2 2 1 3 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain DUF3727 PF12527.8 ORY15540.1 - 1.9 8.8 0.0 1.9 8.8 0.0 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF3727) Nop14 PF04147.12 ORY15540.1 - 4.3 5.4 20.1 6.5 4.8 20.1 1.2 1 0 0 1 1 1 0 Nop14-like family Cwf_Cwc_15 PF04889.12 ORY15540.1 - 4.8 6.8 22.0 10 5.8 22.0 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein HLH PF00010.26 ORY15541.1 - 9.2e-14 51.1 0.2 1.6e-13 50.4 0.2 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain FAM176 PF14851.6 ORY15541.1 - 0.1 12.3 1.5 0.19 11.4 1.5 1.4 1 0 0 1 1 1 0 FAM176 family NOA36 PF06524.12 ORY15541.1 - 0.21 10.9 1.2 0.3 10.4 1.2 1.2 1 0 0 1 1 1 0 NOA36 protein MFS_1 PF07690.16 ORY15542.1 - 6.9e-48 163.4 33.1 6.9e-48 163.4 33.1 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY15542.1 - 1.7e-13 50.3 26.9 7.1e-13 48.2 26.9 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 ORY15542.1 - 0.00039 19.0 1.7 0.00039 19.0 1.7 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 ORY15542.1 - 0.011 14.2 0.5 0.016 13.6 0.5 1.2 1 0 0 1 1 1 0 Transmembrane secretion effector OATP PF03137.20 ORY15542.1 - 1.3 7.2 12.2 0.56 8.4 6.9 2.6 1 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 ORY15544.1 - 1e-35 123.3 37.5 1e-35 123.3 37.5 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Peptidase_M49 PF03571.15 ORY15545.1 - 1.3e-247 822.6 0.0 1.5e-247 822.4 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M49 Glyco_hydro_16 PF00722.21 ORY15546.1 - 1.5e-08 34.3 1.9 2.5e-08 33.6 1.9 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 DENN PF02141.21 ORY15547.1 - 6.2e-41 140.4 0.1 1.1e-40 139.6 0.1 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 ORY15547.1 - 4.3e-06 27.4 0.2 1.4e-05 25.7 0.0 2.0 2 0 0 2 2 2 1 uDENN domain Elongin_A PF06881.11 ORY15547.1 - 0.012 16.2 5.5 0.012 16.2 5.5 2.4 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A AAT PF03417.16 ORY15547.1 - 0.023 14.4 2.9 2.3 7.8 0.4 2.5 2 0 0 2 2 2 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase ERM PF00769.19 ORY15547.1 - 0.47 10.2 20.6 0.82 9.4 20.6 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Cnn_1N PF07989.11 ORY15547.1 - 1.9 8.7 14.1 0.23 11.6 3.2 2.7 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 KASH_CCD PF14662.6 ORY15547.1 - 2.2 8.1 20.7 51 3.6 20.7 2.4 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH GAS PF13851.6 ORY15547.1 - 3.4 7.0 24.5 1.8 7.9 17.2 2.6 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding TolA_bind_tri PF16331.5 ORY15547.1 - 5.2 7.2 16.5 4.7 7.4 3.0 2.9 2 0 0 2 2 2 0 TolA binding protein trimerisation DUF3450 PF11932.8 ORY15547.1 - 7.9 5.7 18.7 1.1 8.5 6.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) zf-HIT PF04438.16 ORY15548.1 - 1.1e-06 28.4 8.7 2e-06 27.5 8.7 1.5 1 0 0 1 1 1 1 HIT zinc finger E3_binding PF02817.17 ORY15549.1 - 0.076 13.4 0.2 4.1 7.8 0.0 2.4 2 0 0 2 2 2 0 e3 binding domain Kinesin PF00225.23 ORY15551.1 - 4.2e-93 311.9 0.0 1.4e-92 310.2 0.0 1.9 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 ORY15551.1 - 3.2e-21 75.8 0.1 1e-16 61.2 0.0 4.1 3 1 0 4 4 4 2 Microtubule binding DUF3800 PF12686.7 ORY15551.1 - 0.018 15.6 0.4 35 5.1 0.0 5.3 3 2 0 3 3 3 0 Protein of unknown function (DUF3800) ZapB PF06005.12 ORY15551.1 - 0.13 12.8 0.0 0.13 12.8 0.0 15.0 7 5 7 14 14 14 0 Cell division protein ZapB F-box-like PF12937.7 ORY15552.1 - 0.014 15.3 0.2 0.04 13.8 0.2 1.8 1 0 0 1 1 1 0 F-box-like 2-oxoacid_dh PF00198.23 ORY15553.1 - 6.6e-73 245.0 0.0 1.8e-72 243.6 0.0 1.6 2 0 0 2 2 2 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 ORY15553.1 - 1e-19 70.1 0.1 3.4e-19 68.4 0.0 1.8 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.17 ORY15553.1 - 3.1e-12 46.6 0.0 1e-11 44.9 0.0 1.9 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 ORY15553.1 - 0.022 14.6 0.0 0.55 10.1 0.0 2.4 1 1 1 2 2 2 0 Biotin-lipoyl like HlyD_D23 PF16576.5 ORY15553.1 - 0.12 11.6 0.0 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion SKI PF01202.22 ORY15554.1 - 9.1e-12 45.4 0.0 1.2e-11 45.0 0.0 1.2 1 0 0 1 1 1 1 Shikimate kinase AAA_18 PF13238.6 ORY15554.1 - 3.7e-10 40.5 0.0 6.1e-10 39.8 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 ORY15554.1 - 6.8e-10 39.3 0.0 9.2e-10 38.8 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 ORY15554.1 - 4.4e-08 33.6 0.0 1e-07 32.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain Rad17 PF03215.15 ORY15554.1 - 2.3e-07 30.9 0.0 4.5e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain Cytidylate_kin PF02224.18 ORY15554.1 - 4.6e-07 29.8 0.0 2.2e-06 27.6 0.0 1.9 1 1 0 2 2 2 1 Cytidylate kinase dNK PF01712.19 ORY15554.1 - 2.7e-06 27.4 0.1 0.0096 15.8 0.0 2.1 1 1 0 2 2 2 2 Deoxynucleoside kinase AAA_22 PF13401.6 ORY15554.1 - 5.5e-06 26.7 0.0 1.3e-05 25.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ORY15554.1 - 0.00011 22.7 0.0 0.00026 21.4 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.6 ORY15554.1 - 0.00027 21.2 0.0 0.00057 20.2 0.0 1.5 2 0 0 2 2 1 1 AAA domain ABC_tran PF00005.27 ORY15554.1 - 0.0015 19.0 0.0 0.0027 18.2 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA PF00004.29 ORY15554.1 - 0.0016 18.9 0.0 0.0024 18.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 ORY15554.1 - 0.0035 17.1 0.0 0.0061 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 ORY15554.1 - 0.0036 17.3 0.0 0.0068 16.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 ORY15554.1 - 0.006 16.0 0.0 0.012 15.0 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Ploopntkinase1 PF18748.1 ORY15554.1 - 0.0062 16.1 0.1 0.69 9.4 0.0 2.1 2 0 0 2 2 2 1 P-loop Nucleotide Kinase1 NTPase_1 PF03266.15 ORY15554.1 - 0.014 15.3 0.1 0.31 10.9 0.0 2.2 2 0 0 2 2 2 0 NTPase APS_kinase PF01583.20 ORY15554.1 - 0.017 15.0 0.0 0.023 14.6 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase RNA_helicase PF00910.22 ORY15554.1 - 0.017 15.5 0.0 0.032 14.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_5 PF07728.14 ORY15554.1 - 0.022 14.8 0.0 0.04 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) tRNA_lig_kinase PF08303.11 ORY15554.1 - 0.025 14.7 0.0 0.052 13.6 0.0 1.6 1 1 0 1 1 1 0 tRNA ligase kinase domain NACHT PF05729.12 ORY15554.1 - 0.026 14.4 0.0 0.063 13.2 0.0 1.6 1 0 0 1 1 1 0 NACHT domain CoaE PF01121.20 ORY15554.1 - 0.029 14.0 0.0 0.051 13.2 0.0 1.4 1 0 0 1 1 1 0 Dephospho-CoA kinase AAA_7 PF12775.7 ORY15554.1 - 0.032 13.8 0.0 0.048 13.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region T2SSE_N PF05157.15 ORY15554.1 - 0.04 14.2 0.0 0.081 13.2 0.0 1.6 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein E, N-terminal domain ADK PF00406.22 ORY15554.1 - 0.043 13.9 0.1 0.69 10.0 0.0 2.1 2 0 0 2 2 2 0 Adenylate kinase T2SSE PF00437.20 ORY15554.1 - 0.046 12.8 0.0 0.095 11.7 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein ATPase_2 PF01637.18 ORY15554.1 - 0.047 13.6 0.0 0.096 12.6 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea PRK PF00485.18 ORY15554.1 - 0.053 13.2 0.0 0.087 12.5 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Cytidylate_kin2 PF13189.6 ORY15554.1 - 0.057 13.6 0.0 0.23 11.6 0.0 1.9 2 0 0 2 2 2 0 Cytidylate kinase-like family Sigma54_activ_2 PF14532.6 ORY15554.1 - 0.065 13.4 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Viral_helicase1 PF01443.18 ORY15554.1 - 0.093 12.4 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 ORY15554.1 - 0.098 13.0 0.0 0.25 11.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 ORY15554.1 - 0.1 12.1 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 ORY15554.1 - 0.11 12.0 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Vps26 PF03643.15 ORY15555.1 - 5.9e-129 428.9 0.4 6.8e-129 428.7 0.4 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 ORY15555.1 - 0.0014 18.7 1.0 0.68 10.0 0.0 3.4 1 1 2 4 4 4 2 Arrestin (or S-antigen), N-terminal domain IL17R_D_N PF16742.5 ORY15555.1 - 0.11 12.6 0.1 0.22 11.6 0.1 1.4 1 0 0 1 1 1 0 N-terminus of interleukin 17 receptor D ESCRT-II PF05871.12 ORY15556.1 - 1.8e-51 174.0 0.1 2.2e-51 173.8 0.1 1.1 1 0 0 1 1 1 1 ESCRT-II complex subunit Death PF00531.22 ORY15556.1 - 0.051 13.7 0.3 0.14 12.4 0.1 1.7 2 0 0 2 2 2 0 Death domain PPR PF01535.20 ORY15556.1 - 0.11 12.8 0.0 0.41 11.0 0.0 2.0 1 0 0 1 1 1 0 PPR repeat PPR_1 PF12854.7 ORY15556.1 - 0.2 11.4 0.0 0.39 10.5 0.0 1.4 1 0 0 1 1 1 0 PPR repeat PTCB-BRCT PF12738.7 ORY15557.1 - 1.6e-30 104.8 6.2 2e-19 69.3 0.4 5.9 5 1 0 5 5 5 2 twin BRCT domain BRCT PF00533.26 ORY15557.1 - 2.9e-25 88.4 0.5 2.2e-11 44.0 0.1 5.0 5 1 0 5 5 5 3 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_5 PF16770.5 ORY15557.1 - 7.4e-25 86.7 0.2 1.3e-21 76.4 0.1 3.8 4 0 0 4 4 4 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT_2 PF16589.5 ORY15557.1 - 5.1e-20 71.7 1.9 2.1e-05 24.9 0.1 6.1 6 1 0 6 6 6 4 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 ORY15557.1 - 1.5e-08 34.8 0.4 0.22 11.8 0.1 4.3 4 0 0 4 4 4 3 DNA ligase 3 BRCT domain PBP1_TM PF14812.6 ORY15557.1 - 0.063 13.6 5.7 0.23 11.9 5.7 2.0 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal BRCT_3 PF18428.1 ORY15557.1 - 0.091 12.8 0.1 0.88 9.7 0.0 2.5 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain PPP4R2 PF09184.11 ORY15557.1 - 2.3 7.7 9.1 4.5 6.8 9.1 1.5 1 0 0 1 1 1 0 PPP4R2 Abhydrolase_6 PF12697.7 ORY15558.1 - 7.4e-13 49.6 0.0 1.5e-12 48.6 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORY15558.1 - 2.6e-07 30.2 0.0 4.7e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ORY15558.1 - 0.00012 21.9 0.0 0.00036 20.3 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 ORY15558.1 - 0.021 13.7 0.0 0.041 12.8 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase enzyme PGAP1 PF07819.13 ORY15558.1 - 0.092 12.4 0.0 0.3 10.8 0.0 1.8 2 0 0 2 2 2 0 PGAP1-like protein TetR_C_11 PF16859.5 ORY15559.1 - 0.01 16.1 2.0 0.022 15.1 0.4 2.1 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain MAT1 PF06391.13 ORY15559.1 - 0.071 12.9 5.0 0.097 12.5 5.0 1.1 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 CI-B14_5a PF07347.12 ORY15559.1 - 1.4 8.9 8.4 0.15 11.9 0.9 2.5 1 1 1 2 2 2 0 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) Ras PF00071.22 ORY15560.1 - 6.4e-19 68.1 0.0 3.1e-14 52.9 0.0 2.2 1 1 1 2 2 2 2 Ras family Roc PF08477.13 ORY15560.1 - 0.0026 18.0 0.0 0.29 11.3 0.0 2.2 1 1 1 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Metallophos PF00149.28 ORY15561.1 - 8.3e-34 117.9 0.0 3.8e-29 102.7 0.0 2.3 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Glyco_hydro_65N PF03636.15 ORY15561.1 - 0.019 14.6 0.0 0.029 14.0 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain Smg4_UPF3 PF03467.15 ORY15562.1 - 3e-37 128.3 0.0 3e-37 128.3 0.0 2.7 3 0 0 3 3 3 1 Smg-4/UPF3 family RRM_1 PF00076.22 ORY15562.1 - 9e-06 25.4 0.0 2.3e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Mito_carr PF00153.27 ORY15563.1 - 8.7e-60 198.7 3.3 7.9e-21 73.8 0.0 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein MT-A70 PF05063.14 ORY15564.1 - 1.2e-28 100.2 0.0 2e-28 99.5 0.0 1.3 1 0 0 1 1 1 1 MT-A70 DUF647 PF04884.14 ORY15566.1 - 0.11 12.0 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Vitamin B6 photo-protection and homoeostasis Stm1_N PF09598.10 ORY15568.1 - 0.7 10.8 9.2 17 6.3 9.2 2.2 1 1 0 1 1 1 0 Stm1 Ras PF00071.22 ORY15571.1 - 1.3e-39 135.4 0.0 2.3e-39 134.6 0.0 1.4 1 1 0 1 1 1 1 Ras family Roc PF08477.13 ORY15571.1 - 7e-13 48.8 0.0 5.8e-12 45.9 0.0 2.0 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY15571.1 - 2.5e-06 27.1 0.0 3.3e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 ORY15571.1 - 0.012 15.6 0.0 0.3 11.0 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase MMR_HSR1_Xtn PF16897.5 ORY15571.1 - 0.019 15.0 0.0 0.036 14.1 0.0 1.5 1 1 0 1 1 1 0 C-terminal region of MMR_HSR1 domain GTP_EFTU PF00009.27 ORY15571.1 - 0.045 13.3 0.0 0.066 12.7 0.0 1.3 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_24 PF13479.6 ORY15571.1 - 0.079 12.7 0.0 0.24 11.1 0.0 1.8 2 1 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 ORY15571.1 - 0.08 13.0 0.0 0.18 11.9 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase Ank_2 PF12796.7 ORY15572.1 - 6e-10 39.6 0.1 6.6e-10 39.4 0.1 1.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY15572.1 - 1.2e-07 32.2 0.0 1.2e-05 25.7 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 ORY15572.1 - 9.7e-06 25.8 1.0 0.33 11.3 0.0 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY15572.1 - 1.1e-05 25.4 0.2 0.018 15.5 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 ORY15572.1 - 1.3e-05 25.4 0.2 0.15 12.6 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Pkinase PF00069.25 ORY15575.1 - 3.8e-54 183.8 0.0 5.8e-54 183.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY15575.1 - 9e-31 107.1 0.0 2.5e-29 102.3 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 ORY15575.1 - 0.032 13.2 0.9 0.038 12.9 0.0 1.5 2 0 0 2 2 2 0 Haspin like kinase domain Pox_ser-thr_kin PF05445.11 ORY15575.1 - 0.067 12.1 0.0 0.1 11.6 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DUF1387 PF07139.11 ORY15575.1 - 2.8 7.6 0.0 2.8 7.6 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1387) Fe_hyd_lg_C PF02906.14 ORY15576.1 - 8.9e-53 179.4 0.0 1.7e-52 178.5 0.0 1.5 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Glyco_transf_25 PF01755.17 ORY15577.1 - 3.5e-11 43.3 0.0 1.4e-10 41.3 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) Ank_2 PF12796.7 ORY15579.1 - 7.3e-21 74.6 0.5 2.6e-09 37.6 0.1 3.6 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ORY15579.1 - 3.5e-16 59.1 1.9 1.1e-06 28.8 0.0 4.8 1 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 ORY15579.1 - 2.4e-14 53.5 0.2 3.6e-06 27.4 0.0 4.5 2 1 3 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 ORY15579.1 - 4.7e-13 48.9 1.7 0.0016 18.8 0.0 5.2 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 ORY15579.1 - 2.3e-10 39.8 0.2 0.023 15.2 0.0 5.6 5 0 0 5 5 4 3 Ankyrin repeat NACHT PF05729.12 ORY15579.1 - 1.3e-05 25.2 0.1 4.8e-05 23.4 0.1 1.9 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 ORY15579.1 - 1.5e-05 25.5 0.0 0.00014 22.3 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 ORY15579.1 - 0.00047 20.4 0.0 0.0017 18.6 0.0 2.0 2 0 0 2 2 1 1 AAA domain KAP_NTPase PF07693.14 ORY15579.1 - 0.0051 16.1 1.6 0.15 11.2 0.1 2.3 1 1 1 2 2 2 1 KAP family P-loop domain AAA PF00004.29 ORY15579.1 - 0.013 15.9 0.2 0.064 13.7 0.2 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 ORY15579.1 - 0.062 13.7 0.0 0.29 11.6 0.0 2.0 2 0 0 2 2 2 0 RNA helicase AAA_30 PF13604.6 ORY15579.1 - 0.13 12.0 0.1 0.42 10.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 ORY15579.1 - 0.17 11.7 0.0 0.46 10.3 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain NmrA PF05368.13 ORY15580.1 - 1.2e-17 64.3 0.0 1.5e-17 63.9 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ORY15580.1 - 7.6e-07 29.2 0.0 1.3e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 ORY15580.1 - 0.0092 15.5 0.0 4.4 6.7 0.0 2.3 1 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 ORY15580.1 - 0.024 14.7 0.0 0.093 12.8 0.0 1.9 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Semialdhyde_dh PF01118.24 ORY15580.1 - 0.043 14.3 0.1 0.65 10.5 0.1 2.3 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain MFS_1 PF07690.16 ORY15581.1 - 3.2e-10 39.5 29.5 3.2e-10 39.5 29.5 2.3 1 1 1 2 2 2 1 Major Facilitator Superfamily Nodulin-like PF06813.13 ORY15581.1 - 1.3e-06 28.1 2.7 1.3e-06 28.1 2.7 2.5 2 1 0 2 2 2 1 Nodulin-like DUF4271 PF14093.6 ORY15581.1 - 0.12 12.3 3.6 0.26 11.2 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4271) 7tm_7 PF08395.12 ORY15581.1 - 0.3 10.2 4.1 0.56 9.3 0.2 2.5 3 0 0 3 3 3 0 7tm Chemosensory receptor EMP70 PF02990.16 ORY15581.1 - 2.6 6.6 5.2 0.82 8.3 1.5 2.0 2 0 0 2 2 2 0 Endomembrane protein 70 RNase_PH PF01138.21 ORY15582.1 - 3.8e-14 53.3 0.0 8.5e-14 52.2 0.0 1.6 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 ORY15582.1 - 0.0007 19.6 0.0 0.0014 18.6 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 SVM_signal PF12113.8 ORY15583.1 - 0.035 14.0 6.3 0.082 12.8 6.3 1.6 1 0 0 1 1 1 0 SVM protein signal sequence SNARE PF05739.19 ORY15585.1 - 1.3e-06 28.3 1.3 2.3e-06 27.5 1.3 1.4 1 0 0 1 1 1 1 SNARE domain Use1 PF09753.9 ORY15585.1 - 0.0021 17.8 0.2 0.0048 16.6 0.2 1.6 1 1 0 1 1 1 1 Membrane fusion protein Use1 Synaptobrevin PF00957.21 ORY15585.1 - 0.067 13.0 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Synaptobrevin CorA PF01544.18 ORY15585.1 - 0.13 11.6 0.0 0.13 11.6 0.0 2.8 3 0 0 3 3 3 0 CorA-like Mg2+ transporter protein Pantoate_transf PF02548.15 ORY15585.1 - 0.19 11.0 0.0 0.3 10.4 0.0 1.1 1 0 0 1 1 1 0 Ketopantoate hydroxymethyltransferase zf-TRAF PF02176.18 ORY15586.1 - 6.1e-09 36.4 30.2 5.1e-06 27.1 2.8 4.4 2 1 4 6 6 5 4 TRAF-type zinc finger zf-C3HC4_4 PF15227.6 ORY15586.1 - 3.3e-07 30.4 7.3 3.3e-07 30.4 7.3 3.2 3 1 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 ORY15586.1 - 4.1e-06 26.5 6.6 4.1e-06 26.5 6.6 3.4 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORY15586.1 - 7.3e-06 25.9 7.4 7.3e-06 25.9 7.4 2.7 2 1 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 ORY15586.1 - 1e-05 25.8 9.6 1e-05 25.8 9.6 3.7 2 1 1 3 3 1 1 Ring finger domain zf-C3HC4 PF00097.25 ORY15586.1 - 3.3e-05 23.6 8.1 3.3e-05 23.6 8.1 3.1 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 ORY15586.1 - 0.00012 21.8 7.5 0.00012 21.8 7.5 3.5 2 1 0 2 2 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 ORY15586.1 - 0.00013 21.7 10.3 0.00013 21.7 10.3 3.6 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORY15586.1 - 0.00017 21.5 8.7 0.00017 21.5 8.7 2.6 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_4 PF14570.6 ORY15586.1 - 0.0047 16.7 4.6 0.0047 16.7 4.6 4.4 4 1 2 6 6 6 1 RING/Ubox like zinc-binding domain zf-ACC PF17848.1 ORY15586.1 - 0.0089 16.1 8.5 0.16 12.1 0.4 3.7 3 0 0 3 3 3 2 Acetyl-coA carboxylase zinc finger domain zf-TRAF_2 PF15965.5 ORY15586.1 - 0.042 14.3 26.4 0.15 12.5 11.6 3.2 2 2 0 2 2 2 0 TRAF-like zinc-finger zf-UDP PF14569.6 ORY15586.1 - 0.5 10.5 14.0 0.63 10.2 2.3 3.1 2 2 0 2 2 2 0 Zinc-binding RING-finger Zn-ribbon_8 PF09723.10 ORY15586.1 - 7.3 6.8 17.7 12 6.1 1.5 3.9 2 1 1 3 3 3 0 Zinc ribbon domain Het-C PF07217.11 ORY15587.1 - 1.6e-273 908.4 0.0 1.9e-273 908.1 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C Condensin2nSMC PF12422.8 ORY15587.1 - 0.00017 21.8 0.0 0.1 12.8 0.0 2.3 1 1 1 2 2 2 2 Condensin II non structural maintenance of chromosomes subunit Ank_4 PF13637.6 ORY15588.1 - 1.3e-34 118.1 1.5 7.5e-08 32.8 0.0 4.3 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 ORY15588.1 - 1.4e-28 99.2 0.7 6e-16 58.8 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ORY15588.1 - 1.3e-26 92.3 4.1 8.5e-08 32.3 0.1 4.1 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 ORY15588.1 - 3.8e-20 71.4 2.1 0.0007 19.9 0.1 5.2 5 0 0 5 5 5 5 Ankyrin repeat Ank_3 PF13606.6 ORY15588.1 - 1.4e-19 68.1 0.4 0.002 18.5 0.0 4.7 5 0 0 5 5 5 4 Ankyrin repeat Ank_2 PF12796.7 ORY15589.1 - 5.7e-22 78.1 0.2 5.9e-07 30.0 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ORY15589.1 - 1.1e-20 71.5 1.7 0.007 16.8 0.0 5.3 5 0 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.6 ORY15589.1 - 2.9e-20 72.4 2.3 1.7e-07 31.6 0.0 4.2 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 ORY15589.1 - 3.8e-18 65.1 1.0 0.032 14.7 0.1 5.3 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.6 ORY15589.1 - 1.9e-16 59.9 3.0 3.1e-05 24.2 0.2 5.2 2 2 3 5 5 5 5 Ankyrin repeats (many copies) DUF2802 PF10975.8 ORY15589.1 - 0.0026 17.8 0.0 0.16 12.1 0.0 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2802) Borrelia_P83 PF05262.11 ORY15590.1 - 0.51 8.8 10.5 0.89 8.0 10.5 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein KBP_C PF12309.8 ORY15590.1 - 3.8 6.9 7.5 6.6 6.2 7.5 1.3 1 0 0 1 1 1 0 KIF-1 binding protein C terminal TSC22 PF01166.18 ORY15591.1 - 0.0065 16.8 3.9 0.078 13.3 0.1 3.3 3 0 0 3 3 3 1 TSC-22/dip/bun family DUF4376 PF14301.6 ORY15591.1 - 0.098 13.0 0.6 0.3 11.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4376) Fez1 PF06818.15 ORY15591.1 - 0.17 12.3 21.8 1.7 9.0 12.2 2.9 1 1 1 2 2 2 0 Fez1 Spc7 PF08317.11 ORY15591.1 - 0.27 10.1 20.0 0.17 10.8 11.5 2.4 1 1 1 2 2 2 0 Spc7 kinetochore protein PARP_reg PF02877.14 ORY15591.1 - 1.6 8.9 6.5 0.71 10.0 1.1 2.7 1 1 2 3 3 3 0 Poly(ADP-ribose) polymerase, regulatory domain ALMT PF11744.8 ORY15591.1 - 4.5 6.0 8.3 8.1 5.2 8.3 1.4 1 0 0 1 1 1 0 Aluminium activated malate transporter LPP PF04728.13 ORY15591.1 - 5.2 7.5 8.0 58 4.2 0.1 3.9 3 0 0 3 3 3 0 Lipoprotein leucine-zipper UBD PF16455.5 ORY15592.1 - 1.2e-27 96.1 0.1 1.7e-27 95.7 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-binding domain PH_6 PF15406.6 ORY15593.1 - 1.2e-30 106.0 1.9 1.2e-30 106.0 1.9 2.7 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 ORY15593.1 - 4.6e-06 27.1 0.0 1.8e-05 25.2 0.0 2.2 1 1 0 1 1 1 1 PH domain DEPP PF15343.6 ORY15593.1 - 0.057 13.5 4.9 0.59 10.2 4.5 2.6 2 0 0 2 2 2 0 Decidual protein induced by progesterone family Sulfate_transp PF00916.20 ORY15595.1 - 1.4e-62 211.7 21.9 2.2e-62 211.0 21.9 1.3 1 0 0 1 1 1 1 Sulfate permease family cNMP_binding PF00027.29 ORY15595.1 - 2.4e-14 53.2 0.1 1.6e-13 50.6 0.0 2.2 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain STAS PF01740.21 ORY15595.1 - 2.4e-11 43.3 0.1 5e-11 42.3 0.1 1.4 1 0 0 1 1 1 1 STAS domain DUF3432 PF11914.8 ORY15595.1 - 0.28 11.4 9.2 0.08 13.2 5.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3432) Sld5 PF05916.11 ORY15596.1 - 2.7e-15 56.8 0.0 3.9e-15 56.3 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein FliT PF05400.13 ORY15596.1 - 0.065 14.0 0.1 0.6 11.0 0.1 2.5 3 0 0 3 3 3 0 Flagellar protein FliT HMG_box PF00505.19 ORY15597.1 - 2.7e-08 34.1 0.2 4.9e-08 33.3 0.2 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box Zn_clus PF00172.18 ORY15598.1 - 9.5e-10 38.4 10.5 1.5e-09 37.8 10.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 ORY15599.1 - 4.6e-24 85.0 52.2 1.3e-16 60.5 31.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Ferritin_2 PF13668.6 ORY15600.1 - 2.4e-39 134.6 3.2 3.6e-39 134.1 3.2 1.3 1 0 0 1 1 1 1 Ferritin-like domain CAP_N PF01213.19 ORY15600.1 - 0.15 11.5 0.5 0.21 11.0 0.5 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal RNB PF00773.19 ORY15602.1 - 2.3e-87 293.4 0.0 4.1e-87 292.5 0.0 1.5 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 ORY15602.1 - 2.2e-26 91.7 0.0 7.6e-26 90.0 0.0 2.0 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Dis3l2_C_term PF17877.1 ORY15602.1 - 4.4e-26 91.0 0.9 6e-25 87.4 0.0 2.8 2 0 0 2 2 2 1 DIS3-like exonuclease 2 C terminal CSD2 PF17876.1 ORY15602.1 - 5.5e-05 23.3 0.0 0.032 14.4 0.0 3.0 2 0 0 2 2 2 2 Cold shock domain Rrp44_CSD1 PF17216.3 ORY15602.1 - 0.0027 17.5 0.0 0.0055 16.4 0.0 1.4 1 0 0 1 1 1 1 Rrp44-like cold shock domain Rrp44_S1 PF17215.3 ORY15602.1 - 0.053 13.5 0.0 0.15 12.0 0.0 1.8 1 0 0 1 1 1 0 S1 domain GLE1 PF07817.13 ORY15603.1 - 3.5e-34 118.2 0.1 2.9e-33 115.1 0.0 2.0 2 0 0 2 2 2 1 GLE1-like protein Phage_integr_3 PF16795.5 ORY15603.1 - 0.094 12.6 0.7 2.7 7.9 0.0 2.5 3 0 0 3 3 3 0 Archaeal phage integrase ParD_like PF11903.8 ORY15603.1 - 0.63 10.2 7.3 0.4 10.8 0.9 2.7 2 0 0 2 2 2 0 ParD-like antitoxin of type II bacterial toxin-antitoxin system CPDase PF07823.11 ORY15604.1 - 3e-30 105.4 0.0 3.4e-30 105.2 0.0 1.0 1 0 0 1 1 1 1 Cyclic phosphodiesterase-like protein 2_5_RNA_ligase2 PF13563.6 ORY15604.1 - 0.00031 20.7 0.1 0.54 10.2 0.0 2.1 1 1 1 2 2 2 2 2'-5' RNA ligase superfamily DUF3336 PF11815.8 ORY15605.1 - 3.1e-34 117.6 0.1 5.2e-34 116.9 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 ORY15605.1 - 3.4e-08 33.9 0.1 7.8e-08 32.7 0.0 1.7 2 0 0 2 2 2 1 Patatin-like phospholipase Glyco_hydro_35 PF01301.19 ORY15606.1 - 2.7e-91 306.5 0.1 4.5e-91 305.8 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 ORY15606.1 - 1.1e-57 193.5 1.6 5.7e-30 104.2 0.0 2.8 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.9 ORY15606.1 - 8.1e-55 185.4 6.9 8.1e-55 185.4 6.9 1.6 2 0 0 2 2 2 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.6 ORY15606.1 - 9.8e-20 69.9 0.0 4e-19 67.9 0.0 2.0 2 0 0 2 2 2 1 Beta-galactosidase, domain 3 Adeno_E3 PF06040.11 ORY15607.1 - 0.14 12.3 0.4 0.35 11.0 0.1 1.8 1 1 1 2 2 2 0 Adenovirus E3 protein PAGK PF15284.6 ORY15607.1 - 0.43 10.5 3.6 0.56 10.1 0.5 2.6 2 1 0 2 2 2 0 Phage-encoded virulence factor Fungal_trans PF04082.18 ORY15610.1 - 1.3e-21 76.9 0.1 2.2e-21 76.1 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY15610.1 - 9.5e-05 22.4 8.4 0.00017 21.6 8.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.25 ORY15612.1 - 4.1e-60 203.4 0.1 9.8e-60 202.1 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY15612.1 - 6.9e-35 120.6 0.0 1.2e-34 119.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.16 ORY15612.1 - 2.3e-28 98.1 10.5 2.8e-15 56.2 4.9 2.5 2 0 0 2 2 2 2 Hr1 repeat C1_1 PF00130.22 ORY15612.1 - 5.3e-21 74.3 31.7 8.7e-13 47.9 10.5 2.4 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.24 ORY15612.1 - 6.4e-14 52.4 1.5 2.7e-13 50.4 1.5 2.2 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 ORY15612.1 - 0.0099 15.2 0.0 0.023 14.1 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Uds1 PF15456.6 ORY15612.1 - 0.029 14.5 1.4 0.32 11.2 0.3 2.4 2 0 0 2 2 2 0 Up-regulated During Septation DUF3176 PF11374.8 ORY15613.1 - 1.1e-09 38.4 2.6 1.8e-09 37.7 2.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) WD40 PF00400.32 ORY15614.1 - 8.1e-06 26.5 4.0 18 6.4 0.1 5.7 5 0 0 5 5 5 2 WD domain, G-beta repeat Lactonase PF10282.9 ORY15614.1 - 0.0097 15.2 0.0 0.035 13.4 0.0 1.9 2 0 0 2 2 2 1 Lactonase, 7-bladed beta-propeller N-glycanase_N PF09112.10 ORY15614.1 - 0.054 13.3 0.0 0.095 12.5 0.0 1.3 1 0 0 1 1 1 0 Peptide-N-glycosidase F, N terminal Mito_carr PF00153.27 ORY15615.1 - 2.1e-40 136.6 3.2 7.4e-17 61.1 0.2 4.2 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 ORY15615.1 - 0.0018 17.5 0.1 0.076 12.2 0.0 2.2 2 0 0 2 2 2 2 Gammaproteobacterial serine protease DUF3337 PF11816.8 ORY15616.1 - 3.4e-56 189.8 0.0 7.1e-56 188.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3337) WD40 PF00400.32 ORY15616.1 - 3.4e-18 65.7 13.1 0.00022 21.9 0.2 6.8 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.8 ORY15616.1 - 0.02 13.5 0.3 0.02 13.5 0.3 1.9 2 0 0 2 2 2 0 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 ORY15616.1 - 0.25 11.7 0.6 1.5 9.2 0.1 2.6 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Myb_Cef PF11831.8 ORY15617.1 - 1.3e-53 182.0 3.1 1.3e-53 182.0 3.1 3.5 5 1 0 5 5 5 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.31 ORY15617.1 - 2.6e-19 69.1 5.1 1.8e-09 37.6 1.6 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORY15617.1 - 6.4e-16 58.4 3.2 1.1e-10 41.5 2.8 2.7 1 1 1 2 2 2 2 Myb-like DNA-binding domain BST2 PF16716.5 ORY15618.1 - 0.0041 17.7 0.9 0.0049 17.4 0.9 1.1 1 0 0 1 1 1 1 Bone marrow stromal antigen 2 Ig_mannosidase PF17753.1 ORY15621.1 - 1.4e-21 76.1 0.2 3.3e-21 74.8 0.2 1.7 1 0 0 1 1 1 1 Ig-fold domain Mannosidase_ig PF17786.1 ORY15621.1 - 6e-14 52.4 0.1 1.7e-13 51.0 0.1 1.8 1 0 0 1 1 1 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 ORY15621.1 - 4.8e-07 30.4 0.0 1.4e-06 28.9 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 SnoaL_2 PF12680.7 ORY15622.1 - 0.00033 21.3 0.1 0.00036 21.1 0.1 1.2 1 0 0 1 1 1 1 SnoaL-like domain RecC_C PF17946.1 ORY15625.1 - 0.011 15.5 0.1 0.028 14.2 0.0 1.6 2 0 0 2 2 2 0 RecC C-terminal domain IBN_N PF03810.19 ORY15626.1 - 5.1e-11 42.3 0.0 5.5e-10 39.0 0.0 2.8 3 0 0 3 3 3 1 Importin-beta N-terminal domain Xpo1 PF08389.12 ORY15626.1 - 0.0025 17.9 0.0 2.3 8.3 0.0 3.3 3 1 0 3 3 3 2 Exportin 1-like protein RIG-I_C PF18119.1 ORY15626.1 - 0.035 14.1 0.0 0.13 12.3 0.0 1.9 2 0 0 2 2 2 0 RIG-I receptor C-terminal domain HORMA PF02301.18 ORY15627.1 - 2.2e-08 34.0 0.0 3.4e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 HORMA domain GCIP PF13324.6 ORY15627.1 - 0.061 12.9 0.3 0.075 12.6 0.3 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting TFB6 PF17110.5 ORY15627.1 - 0.22 11.3 2.5 0.35 10.6 2.5 1.3 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH CDC45 PF02724.14 ORY15627.1 - 0.27 9.5 4.2 0.36 9.1 4.2 1.1 1 0 0 1 1 1 0 CDC45-like protein RRN3 PF05327.11 ORY15627.1 - 0.46 9.0 2.6 0.53 8.8 2.6 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DNA_pol_phi PF04931.13 ORY15627.1 - 0.48 8.5 10.7 0.57 8.2 10.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi FAM176 PF14851.6 ORY15627.1 - 1.6 8.4 4.1 3.1 7.4 4.1 1.4 1 0 0 1 1 1 0 FAM176 family COPI_C PF06957.11 ORY15627.1 - 3.3 6.4 7.4 6.3 5.4 1.2 2.1 2 0 0 2 2 2 0 Coatomer (COPI) alpha subunit C-terminus Thr_synth_N PF14821.6 ORY15628.1 - 8.5e-29 99.6 0.0 2.3e-28 98.2 0.0 1.8 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.25 ORY15628.1 - 2.3e-19 69.9 0.0 1.7e-18 67.1 0.0 2.0 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Acetyltransf_7 PF13508.7 ORY15630.1 - 0.00072 19.9 0.0 0.0014 19.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 ORY15630.1 - 0.0059 16.7 0.1 0.017 15.2 0.1 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORY15630.1 - 0.015 15.5 0.0 0.048 13.9 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ORY15630.1 - 0.038 13.9 0.0 0.077 12.9 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 ORY15630.1 - 0.1 12.6 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein IBR PF01485.21 ORY15631.1 - 0.0026 18.0 8.1 0.0026 18.0 8.1 3.6 2 1 1 3 3 3 1 IBR domain, a half RING-finger domain DNA_ligase_A_M PF01068.21 ORY15632.1 - 1.4e-61 207.7 0.6 7.1e-49 166.2 0.3 2.3 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 ORY15632.1 - 6e-45 153.7 0.1 1.1e-44 152.8 0.1 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 ORY15632.1 - 7.6e-29 100.2 0.0 2.3e-28 98.7 0.0 1.9 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 ORY15632.1 - 2.1e-07 31.4 0.1 3.2e-07 30.8 0.1 1.3 1 0 0 1 1 1 1 RNA ligase Cid2 PF09774.9 ORY15633.1 - 5.8e-53 179.6 0.3 7.2e-53 179.3 0.3 1.1 1 0 0 1 1 1 1 Caffeine-induced death protein 2 Ribosomal_L1 PF00687.21 ORY15634.1 - 6.8e-47 159.8 0.3 7.8e-47 159.6 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Ndr PF03096.14 ORY15634.1 - 0.036 12.8 0.0 0.059 12.1 0.0 1.3 1 0 0 1 1 1 0 Ndr family Rcd1 PF04078.13 ORY15635.1 - 8.2e-123 408.7 3.3 1e-122 408.5 3.3 1.1 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like DUF4407 PF14362.6 ORY15635.1 - 0.16 11.3 7.2 0.26 10.6 7.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TAF4 PF05236.14 ORY15635.1 - 1.4 8.6 8.3 2.2 8.0 8.3 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family Med15 PF09606.10 ORY15635.1 - 1.5 7.4 26.9 1.7 7.2 26.9 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal TFIIA PF03153.13 ORY15635.1 - 4.2 7.3 13.3 5.1 7.0 13.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ThylakoidFormat PF11264.8 ORY15635.1 - 6 6.5 10.1 46 3.6 8.9 2.7 3 0 0 3 3 3 0 Thylakoid formation protein baeRF_family10 PF18854.1 ORY15635.1 - 8.6 6.6 14.2 55 4.0 0.1 2.7 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 10 Pkinase PF00069.25 ORY15636.1 - 8.4e-73 245.0 0.0 1.3e-72 244.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY15636.1 - 1.8e-41 142.2 0.1 5.3e-41 140.6 0.1 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 ORY15636.1 - 4.2e-18 64.9 0.4 7.8e-18 64.0 0.4 1.5 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.6 ORY15636.1 - 2.3e-06 27.1 0.0 2.4e-05 23.8 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 ORY15636.1 - 6.1e-06 25.4 0.0 1.1e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 ORY15636.1 - 1.5e-05 24.5 0.1 2.7e-05 23.6 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 ORY15636.1 - 0.00055 19.9 0.3 0.011 15.6 0.1 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 ORY15636.1 - 0.035 13.7 0.1 0.11 12.1 0.1 1.8 1 0 0 1 1 1 0 RIO1 family WaaY PF06176.11 ORY15636.1 - 0.044 13.4 0.1 0.076 12.6 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) YrbL-PhoP_reg PF10707.9 ORY15636.1 - 0.054 13.0 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL DUF1604 PF07713.13 ORY15637.1 - 1.6e-40 136.8 1.0 5.2e-40 135.2 1.0 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF1604) G-patch PF01585.23 ORY15637.1 - 1.1e-06 28.4 1.6 2.1e-06 27.5 0.4 2.1 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 ORY15637.1 - 0.087 12.9 0.2 0.45 10.6 0.2 2.3 1 0 0 1 1 1 0 G-patch domain GST_C_3 PF14497.6 ORY15638.1 - 1e-14 54.5 0.0 2e-14 53.6 0.0 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 ORY15638.1 - 2.6e-05 24.4 0.0 0.00057 20.2 0.0 2.5 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 ORY15638.1 - 0.00066 19.8 0.0 0.001 19.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 ORY15638.1 - 0.11 12.9 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 ORY15638.1 - 0.18 11.9 0.0 0.49 10.5 0.0 1.9 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain NAD_binding_10 PF13460.6 ORY15639.1 - 3.7e-16 59.5 0.0 6.3e-16 58.8 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 ORY15639.1 - 1.1e-09 38.1 0.0 1.7e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 ORY15639.1 - 8.8e-07 28.7 0.1 1e-06 28.5 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.17 ORY15639.1 - 3.5e-06 26.3 0.1 5e-06 25.8 0.1 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 ORY15639.1 - 8e-06 25.5 0.0 1e-05 25.1 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 ORY15639.1 - 4.8e-05 22.9 0.0 7.3e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase TrkA_N PF02254.18 ORY15639.1 - 0.0005 20.3 0.1 0.00099 19.3 0.1 1.5 1 0 0 1 1 1 1 TrkA-N domain Semialdhyde_dh PF01118.24 ORY15639.1 - 0.0026 18.2 0.1 0.0042 17.5 0.1 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 ORY15639.1 - 0.03 13.5 0.0 0.051 12.7 0.0 1.3 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein KR PF08659.10 ORY15639.1 - 0.042 13.7 0.0 0.071 13.0 0.0 1.3 1 0 0 1 1 1 0 KR domain 3Beta_HSD PF01073.19 ORY15639.1 - 0.047 12.7 0.0 0.061 12.3 0.0 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_2 PF03446.15 ORY15639.1 - 0.059 13.5 0.0 0.086 13.0 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_4 PF07993.12 ORY15639.1 - 0.13 11.4 0.1 0.2 10.8 0.1 1.4 1 1 0 1 1 1 0 Male sterility protein HlyIII PF03006.20 ORY15640.1 - 1.6e-46 158.9 15.3 1.8e-46 158.7 15.3 1.0 1 0 0 1 1 1 1 Haemolysin-III related Presenilin PF01080.17 ORY15640.1 - 0.95 8.2 3.4 1.3 7.7 3.4 1.2 1 0 0 1 1 1 0 Presenilin AAA_12 PF13087.6 ORY15668.1 - 1.1e-27 97.0 0.0 2e-27 96.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 ORY15668.1 - 1.1e-21 77.9 0.0 6e-21 75.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 ORY15668.1 - 2.8e-09 37.5 0.0 1.6e-08 35.0 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 ORY15668.1 - 8.6e-08 32.1 0.0 0.0002 21.1 0.0 2.3 2 0 0 2 2 2 2 AAA domain DUF2075 PF09848.9 ORY15668.1 - 0.00092 18.5 0.0 0.0028 17.0 0.0 1.8 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_18 PF13238.6 ORY15668.1 - 0.0051 17.4 0.6 0.42 11.2 0.0 3.3 3 0 0 3 3 3 1 AAA domain ResIII PF04851.15 ORY15668.1 - 0.0069 16.4 0.0 0.014 15.4 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_5 PF07728.14 ORY15668.1 - 0.017 15.1 0.0 0.049 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 ORY15668.1 - 0.035 14.4 0.0 0.16 12.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 ORY15668.1 - 0.084 13.3 0.0 0.97 9.9 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Adeno_IVa2 PF02456.15 ORY15668.1 - 0.085 11.6 0.0 0.17 10.7 0.0 1.4 1 0 0 1 1 1 0 Adenovirus IVa2 protein AAA_25 PF13481.6 ORY15668.1 - 0.14 11.8 0.0 0.3 10.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain TrkH PF02386.16 ORY15670.1 - 3.5e-104 349.0 7.9 1.4e-100 337.2 1.7 2.1 2 0 0 2 2 2 2 Cation transport protein Senescence PF06911.12 ORY15671.1 - 2.1e-55 187.9 5.9 2.9e-55 187.4 5.9 1.2 1 0 0 1 1 1 1 Senescence-associated protein DUF3082 PF11282.8 ORY15671.1 - 0.038 14.2 0.0 0.11 12.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3082) DUF1479 PF07350.12 ORY15672.1 - 4.4e-162 539.6 0.0 5.1e-162 539.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) PhyH PF05721.13 ORY15672.1 - 0.059 13.6 0.1 2.2 8.5 0.1 2.3 2 0 0 2 2 2 0 Phytanoyl-CoA dioxygenase (PhyH) Glyco_hydro_1 PF00232.18 ORY15673.1 - 3.4e-151 503.7 0.0 4.5e-151 503.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Glyco_hydro_65m PF03632.15 ORY15674.1 - 0.11 11.3 0.1 0.18 10.6 0.1 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65 central catalytic domain TSC22 PF01166.18 ORY15675.1 - 8.2e-05 22.8 3.6 0.0012 19.1 0.3 2.4 1 1 1 2 2 2 1 TSC-22/dip/bun family bZIP_1 PF00170.21 ORY15675.1 - 0.0002 21.4 13.4 0.0081 16.2 12.2 2.2 1 1 1 2 2 2 2 bZIP transcription factor YabA PF06156.13 ORY15675.1 - 0.0016 19.0 0.1 0.0033 18.0 0.1 1.5 1 0 0 1 1 1 1 Initiation control protein YabA bZIP_2 PF07716.15 ORY15675.1 - 0.039 14.0 14.6 0.28 11.3 0.8 2.3 1 1 1 2 2 2 0 Basic region leucine zipper ABC_tran_CTD PF16326.5 ORY15675.1 - 0.5 10.6 4.7 0.88 9.9 4.7 1.4 1 0 0 1 1 1 0 ABC transporter C-terminal domain DIOX_N PF14226.6 ORY15677.1 - 2.2e-28 99.4 0.0 8e-27 94.3 0.0 2.2 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 ORY15677.1 - 3.8e-12 46.6 0.0 7.5e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MSA-2c PF12238.8 ORY15680.1 - 1 9.3 14.3 2.1 8.3 14.3 1.5 1 0 0 1 1 1 0 Merozoite surface antigen 2c PfkB PF00294.24 ORY15682.1 - 2.2e-11 43.6 0.0 2.9e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase SPRY PF00622.28 ORY15683.1 - 2.8e-06 27.4 0.0 1.8e-05 24.8 0.0 2.2 2 1 0 2 2 2 1 SPRY domain Lactamase_B_3 PF13483.6 ORY15684.1 - 2.2e-05 24.4 0.0 5e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 ORY15684.1 - 0.013 15.0 0.0 0.042 13.3 0.1 1.8 2 0 0 2 2 2 0 Beta-lactamase superfamily domain Spc7 PF08317.11 ORY15685.1 - 0.0011 17.9 1.5 0.0021 17.0 1.5 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF4618 PF15397.6 ORY15685.1 - 0.011 15.1 0.2 0.026 14.0 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) XhlA PF10779.9 ORY15685.1 - 0.016 15.4 0.0 0.053 13.7 0.0 1.9 1 0 0 1 1 1 0 Haemolysin XhlA PG_binding_1 PF01471.18 ORY15685.1 - 0.016 15.4 0.4 2.2 8.6 0.0 3.2 2 1 0 2 2 2 0 Putative peptidoglycan binding domain Filament PF00038.21 ORY15685.1 - 0.023 14.3 1.5 0.041 13.5 1.5 1.3 1 0 0 1 1 1 0 Intermediate filament protein BLOC1_2 PF10046.9 ORY15685.1 - 0.045 14.0 3.0 0.15 12.4 1.2 2.4 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 YkyA PF10368.9 ORY15685.1 - 0.066 12.9 1.2 0.1 12.2 1.2 1.2 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein EzrA PF06160.12 ORY15685.1 - 0.066 11.4 0.8 0.1 10.8 0.8 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA HMMR_N PF15905.5 ORY15685.1 - 0.084 12.3 4.1 0.99 8.8 1.5 2.3 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal DUF812 PF05667.11 ORY15685.1 - 0.089 11.7 0.4 0.16 10.8 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF1664 PF07889.12 ORY15685.1 - 0.089 12.8 2.9 0.05 13.7 0.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) ATG16 PF08614.11 ORY15685.1 - 0.11 12.7 5.9 0.029 14.6 1.7 2.1 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) PDT PF00800.18 ORY15685.1 - 0.14 12.0 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 Prephenate dehydratase FlaC_arch PF05377.11 ORY15685.1 - 0.2 12.1 0.5 0.58 10.6 0.5 1.7 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) PspA_IM30 PF04012.12 ORY15685.1 - 0.21 11.1 2.2 0.51 9.9 2.2 1.6 1 0 0 1 1 1 0 PspA/IM30 family DUF1732 PF08340.11 ORY15685.1 - 0.29 11.1 1.3 6.5 6.8 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1732) Tropomyosin_1 PF12718.7 ORY15685.1 - 2.2 8.4 7.2 0.099 12.8 0.6 2.2 3 0 0 3 3 2 0 Tropomyosin like CLTH PF10607.9 ORY15686.1 - 5.7e-30 104.2 0.0 2e-29 102.4 0.0 1.8 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.6 ORY15686.1 - 3.3e-08 33.4 0.2 6e-08 32.6 0.2 1.5 1 0 0 1 1 1 1 RING-type zinc-finger Rtf2 PF04641.12 ORY15686.1 - 0.001 18.5 0.0 0.002 17.5 0.0 1.4 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_5 PF14634.6 ORY15686.1 - 0.0011 18.9 0.2 0.0022 17.9 0.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 ORY15686.1 - 0.0021 18.4 0.4 0.0037 17.5 0.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 ORY15686.1 - 0.013 15.3 1.0 0.025 14.4 1.0 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 ORY15686.1 - 0.026 14.4 0.3 0.048 13.5 0.3 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 ORY15686.1 - 0.04 13.8 0.6 0.077 12.9 0.6 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 ORY15686.1 - 0.059 13.3 0.5 0.11 12.4 0.5 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Leu_zip PF15294.6 ORY15686.1 - 0.95 8.9 4.6 0.38 10.2 1.4 1.8 2 0 0 2 2 2 0 Leucine zipper DivIC PF04977.15 ORY15686.1 - 4.6 7.1 7.2 1.5 8.6 1.3 2.8 2 1 0 2 2 2 0 Septum formation initiator Ank_2 PF12796.7 ORY15687.1 - 3.6e-25 88.4 5.8 6.5e-09 36.3 0.8 4.6 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ORY15687.1 - 3.8e-23 81.2 5.5 1.1e-07 32.0 0.0 5.2 3 2 1 5 5 5 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 ORY15687.1 - 3.1e-21 75.4 5.1 0.0033 18.0 0.0 5.9 3 2 1 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY15687.1 - 6.6e-17 59.9 3.6 0.019 15.5 0.0 7.0 7 0 0 7 7 7 5 Ankyrin repeat Ank PF00023.30 ORY15687.1 - 3.7e-13 49.3 9.5 0.0045 17.4 0.1 5.8 4 1 1 5 5 5 4 Ankyrin repeat TAL_FSA PF00923.19 ORY15688.1 - 3.9e-31 108.5 0.0 4.9e-31 108.1 0.0 1.1 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase Glyco_transf_25 PF01755.17 ORY15689.1 - 4.7e-10 39.7 0.0 4.5e-09 36.5 0.0 2.3 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) ADH_zinc_N PF00107.26 ORY15691.1 - 9.6e-32 109.7 0.3 1.5e-31 109.1 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ORY15691.1 - 6e-12 46.8 0.0 1e-11 46.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ORY15691.1 - 2.2e-05 24.3 0.0 0.00046 20.1 0.0 2.5 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.18 ORY15691.1 - 0.0062 16.8 0.0 0.012 15.9 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain AlaDh_PNT_C PF01262.21 ORY15691.1 - 0.013 14.8 0.3 0.021 14.2 0.3 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ubiquitin PF00240.23 ORY15692.1 - 5.3e-17 61.3 0.0 8.1e-17 60.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 ORY15692.1 - 4.4e-07 29.7 0.2 9.7e-07 28.6 0.2 1.6 1 0 0 1 1 1 1 UBA/TS-N domain Rad60-SLD PF11976.8 ORY15692.1 - 2.2e-05 24.2 0.0 3.5e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 ORY15692.1 - 0.00014 22.3 0.0 0.00028 21.4 0.0 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain HOIP-UBA PF16678.5 ORY15692.1 - 0.015 15.3 0.3 0.051 13.6 0.0 1.9 2 0 0 2 2 2 0 HOIP UBA domain pair Rad60-SLD_2 PF13881.6 ORY15692.1 - 0.021 14.9 0.0 0.04 14.0 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Blt1 PF12754.7 ORY15692.1 - 0.085 13.2 0.1 0.15 12.4 0.1 1.4 1 0 0 1 1 1 0 Blt1 N-terminal domain LEM PF03020.15 ORY15692.1 - 0.15 11.7 0.0 0.8 9.3 0.0 2.1 2 0 0 2 2 2 0 LEM domain STI1 PF17830.1 ORY15692.1 - 2 8.4 31.3 0.97 9.4 6.9 3.7 2 1 1 3 3 3 0 STI1 domain XPC-binding PF09280.11 ORY15692.1 - 6 6.7 14.9 1.9 8.3 1.0 3.1 2 1 0 2 2 2 0 XPC-binding domain RNA_pol_Rpb2_6 PF00562.28 ORY15693.1 - 8.4e-124 413.6 0.1 1.3e-123 412.9 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 ORY15693.1 - 6e-58 195.7 0.0 1.1e-57 194.8 0.0 1.4 1 1 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 ORY15693.1 - 1.2e-39 135.9 0.0 2.4e-39 134.9 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 ORY15693.1 - 8.1e-33 112.7 0.1 1.8e-32 111.6 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 ORY15693.1 - 1.5e-25 89.1 0.1 3.3e-25 88.1 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.13 ORY15693.1 - 4.9e-22 78.0 0.2 1.2e-21 76.8 0.2 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.17 ORY15693.1 - 1.9e-21 76.4 0.3 6.2e-21 74.7 0.3 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Pro_isomerase PF00160.21 ORY15694.1 - 1.1e-32 113.5 0.0 1.8e-32 112.8 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 ORY15694.1 - 1.9e-14 53.2 0.0 3.3e-14 52.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 ORY15694.1 - 0.053 13.5 0.2 0.25 11.4 0.0 2.0 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Zn_clus PF00172.18 ORY15695.1 - 1.3e-06 28.4 7.1 2.4e-06 27.5 7.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DEC-1_N PF04625.13 ORY15696.1 - 5.9 5.8 6.1 11 4.9 6.1 1.4 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region peroxidase PF00141.23 ORY15697.1 - 1.7e-19 70.5 0.0 2.9e-19 69.7 0.0 1.3 1 0 0 1 1 1 1 Peroxidase F-box-like PF12937.7 ORY15698.1 - 8.7e-12 44.8 0.2 1.5e-11 44.0 0.2 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY15698.1 - 8.2e-07 28.8 0.2 1.7e-06 27.7 0.2 1.6 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 ORY15698.1 - 0.044 13.7 0.2 0.086 12.7 0.2 1.5 1 0 0 1 1 1 0 F-box DLH PF01738.18 ORY15698.1 - 0.091 12.3 0.3 0.15 11.6 0.3 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family DUF3176 PF11374.8 ORY15701.1 - 1.7e-11 44.2 1.4 1.7e-11 44.2 1.4 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) DUF2700 PF10912.8 ORY15701.1 - 0.12 12.4 0.4 0.26 11.3 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2700) DUF3149 PF11346.8 ORY15701.1 - 2.3 7.9 6.0 0.19 11.3 0.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3149) AAA PF00004.29 ORY15704.1 - 9.7e-20 71.3 0.0 2.1e-19 70.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.18 ORY15704.1 - 0.022 14.5 0.1 0.14 11.9 0.0 2.4 4 0 0 4 4 4 0 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.6 ORY15704.1 - 0.029 14.8 0.0 0.23 11.8 0.0 2.2 1 1 1 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 ORY15704.1 - 0.03 14.6 0.0 0.07 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF725 PF05267.12 ORY15704.1 - 0.035 14.1 2.3 0.073 13.1 2.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF725) FtsK_SpoIIIE PF01580.18 ORY15704.1 - 0.13 11.6 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family TRAPP PF04051.16 ORY15706.1 - 2e-34 118.4 0.0 2.5e-34 118.1 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component WD40 PF00400.32 ORY15707.1 - 9.8e-42 140.2 8.0 4e-07 30.6 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY15707.1 - 1.4e-15 57.3 0.0 0.00015 22.0 0.0 4.7 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 ORY15707.1 - 0.00012 20.8 0.2 0.083 11.4 0.0 2.9 1 1 0 3 3 3 2 Cytochrome D1 heme domain Ge1_WD40 PF16529.5 ORY15707.1 - 0.01 14.8 0.0 0.5 9.3 0.0 3.0 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein BBS2_Mid PF14783.6 ORY15707.1 - 0.054 13.5 0.1 18 5.4 0.0 3.1 2 1 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Frtz PF11768.8 ORY15707.1 - 0.06 11.6 0.0 0.28 9.4 0.0 1.9 1 1 1 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz nos_propeller PF18764.1 ORY15707.1 - 0.083 12.8 0.0 0.58 10.1 0.0 2.2 2 0 0 2 2 2 0 Nitrous oxide reductase propeller repeat Nucleoporin_N PF08801.11 ORY15707.1 - 0.13 11.0 0.4 12 4.5 0.1 2.8 1 1 1 3 3 3 0 Nup133 N terminal like Nup160 PF11715.8 ORY15707.1 - 0.34 9.5 0.9 19 3.8 0.0 2.9 2 1 1 3 3 3 0 Nucleoporin Nup120/160 APH PF01636.23 ORY15709.1 - 9.6e-07 29.0 0.1 2.1e-06 27.9 0.1 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 ORY15709.1 - 0.0026 17.2 0.0 0.17 11.2 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Choline_kinase PF01633.20 ORY15709.1 - 0.049 13.2 0.0 0.092 12.3 0.0 1.5 1 1 1 2 2 2 0 Choline/ethanolamine kinase SBDS PF01172.18 ORY15710.1 - 4.4e-24 84.4 0.6 5.2e-24 84.1 0.6 1.0 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein RhoGEF PF00621.20 ORY15712.1 - 6.5e-25 88.4 0.1 1.5e-24 87.3 0.1 1.6 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.29 ORY15712.1 - 0.084 13.4 0.0 0.19 12.2 0.0 1.7 1 0 0 1 1 1 0 PH domain Nas2_N PF18265.1 ORY15713.1 - 8.1e-31 105.8 0.3 1.1e-30 105.3 0.3 1.2 1 0 0 1 1 1 1 Nas2 N_terminal domain PDZ_6 PF17820.1 ORY15713.1 - 1.7e-10 40.6 0.1 3.8e-10 39.5 0.1 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 ORY15713.1 - 6.8e-07 29.5 0.0 1.5e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 ORY15713.1 - 1.9e-06 28.1 0.0 3.8e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.14 ORY15713.1 - 0.00022 21.6 0.0 0.00075 19.8 0.0 1.9 2 1 0 2 2 2 1 GRASP55/65 PDZ-like domain Ras PF00071.22 ORY15714.1 - 1.8e-48 164.2 0.0 2.2e-48 163.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY15714.1 - 2e-28 99.0 0.0 4.7e-28 97.8 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY15714.1 - 8.1e-10 38.4 0.0 1.1e-09 38.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.22 ORY15714.1 - 0.00068 20.0 0.1 0.0042 17.5 0.1 2.1 1 1 0 1 1 1 1 RNA helicase MMR_HSR1 PF01926.23 ORY15714.1 - 0.0013 18.8 0.0 0.0025 17.9 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 ORY15714.1 - 0.0054 16.1 0.0 0.0071 15.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 ORY15714.1 - 0.0074 15.5 0.7 0.48 9.5 0.0 2.4 2 1 1 3 3 3 1 G-protein alpha subunit Pox_A32 PF04665.12 ORY15714.1 - 0.013 14.9 0.1 0.024 14.1 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_7 PF12775.7 ORY15714.1 - 0.033 13.7 0.1 0.054 13.0 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region TsaE PF02367.17 ORY15714.1 - 0.055 13.5 0.1 0.12 12.4 0.1 1.6 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RsgA_GTPase PF03193.16 ORY15714.1 - 0.062 13.2 0.1 4.9 7.0 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase AAA_24 PF13479.6 ORY15714.1 - 0.068 12.9 0.1 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 AAA domain ArgoMid PF16487.5 ORY15714.1 - 0.092 13.0 0.0 0.23 11.7 0.0 1.7 1 1 0 1 1 1 0 Mid domain of argonaute AAA_16 PF13191.6 ORY15714.1 - 0.12 12.8 0.1 0.21 12.0 0.0 1.5 2 0 0 2 2 2 0 AAA ATPase domain AAA_33 PF13671.6 ORY15714.1 - 0.12 12.6 0.5 0.23 11.6 0.2 1.6 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 ORY15714.1 - 0.18 12.2 0.2 2.6 8.4 0.2 2.1 2 0 0 2 2 2 0 AAA domain Septin PF00735.18 ORY15714.1 - 0.18 11.0 1.0 0.21 10.8 0.1 1.5 2 0 0 2 2 2 0 Septin Zn_clus PF00172.18 ORY15715.1 - 5.2e-08 32.9 8.2 8.7e-08 32.2 8.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ORY15715.1 - 4e-06 26.0 0.0 6.1e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Epimerase PF01370.21 ORY15716.1 - 1.1e-36 126.5 0.0 2.1e-28 99.4 0.0 2.7 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ORY15716.1 - 1.4e-34 120.0 0.0 1.5e-26 93.6 0.0 2.6 2 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 ORY15716.1 - 4.3e-07 29.4 0.0 7.9e-05 22.0 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.15 ORY15716.1 - 5.6e-07 29.0 0.0 0.0005 19.3 0.0 3.1 3 0 0 3 3 3 2 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 ORY15716.1 - 3.1e-06 26.4 0.1 0.041 12.9 0.0 2.4 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 ORY15716.1 - 0.012 15.1 0.0 0.026 14.0 0.0 1.5 1 0 0 1 1 1 0 short chain dehydrogenase KR PF08659.10 ORY15716.1 - 0.11 12.4 0.0 15 5.5 0.0 2.3 2 0 0 2 2 2 0 KR domain TrkA_N PF02254.18 ORY15716.1 - 0.18 12.1 0.0 0.33 11.2 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Glyco_hydro_114 PF03537.13 ORY15718.1 - 2.9e-80 268.9 0.0 3.5e-80 268.6 0.0 1.1 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 Polysacc_deac_1 PF01522.21 ORY15719.1 - 0.012 15.5 0.6 0.047 13.6 0.0 2.1 2 0 0 2 2 2 0 Polysaccharide deacetylase Glyco_trans_1_4 PF13692.6 ORY15720.1 - 5.9e-10 39.7 0.0 1.2e-09 38.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 ORY15720.1 - 1.3e-06 28.1 0.0 2.7e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF3492 PF11997.8 ORY15720.1 - 0.0004 20.2 0.1 0.0037 17.1 0.1 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF3492) Peptidase_C48 PF02902.19 ORY15721.1 - 9.9e-05 22.3 0.3 0.00016 21.6 0.2 1.5 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain zf-C2H2_4 PF13894.6 ORY15722.1 - 0.029 15.2 4.3 0.033 15.0 3.3 1.7 1 1 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_6 PF13912.6 ORY15722.1 - 0.092 12.8 5.6 0.14 12.2 5.6 1.3 1 0 0 1 1 1 0 C2H2-type zinc finger ADH_zinc_N PF00107.26 ORY15724.1 - 1.6e-20 73.4 0.0 2.3e-20 72.9 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 ORY15724.1 - 1e-16 60.7 0.0 1.8e-16 60.0 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 ORY15724.1 - 2.1e-06 28.8 0.0 3.4e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Maf PF02545.14 ORY15727.1 - 2.8e-51 173.6 0.0 3.3e-51 173.4 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein Scytalone_dh PF02982.14 ORY15729.1 - 6.9e-89 295.7 0.9 7.9e-89 295.5 0.9 1.0 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.6 ORY15729.1 - 1.3e-08 35.0 0.5 1.7e-08 34.6 0.5 1.1 1 0 0 1 1 1 1 SnoaL-like domain LPD23 PF18838.1 ORY15729.1 - 0.11 12.3 0.7 0.23 11.3 0.7 1.5 1 0 0 1 1 1 0 Large polyvalent protein associated domain 23 RRM_1 PF00076.22 ORY15730.1 - 1.4e-44 149.8 0.0 7.4e-17 60.9 0.0 3.1 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 ORY15730.1 - 0.00018 21.4 0.1 0.0015 18.5 0.0 2.2 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 ORY15730.1 - 0.00023 21.2 0.0 0.0012 18.9 0.0 2.1 3 0 0 3 3 3 1 RNA binding motif RRM_occluded PF16842.5 ORY15730.1 - 0.00069 19.4 0.0 0.056 13.3 0.0 2.4 2 0 0 2 2 2 1 Occluded RNA-recognition motif RRM_7 PF16367.5 ORY15730.1 - 0.0028 17.7 0.4 0.05 13.7 0.0 2.6 3 1 0 3 3 3 1 RNA recognition motif RRM_5 PF13893.6 ORY15730.1 - 0.027 14.1 0.0 0.054 13.1 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nse4_C PF08743.10 ORY15731.1 - 0.31 11.3 1.4 0.59 10.4 0.2 2.1 2 0 0 2 2 2 0 Nse4 C-terminal zinc_ribbon_15 PF17032.5 ORY15732.1 - 2.4e-05 25.0 0.4 3.3e-05 24.6 0.4 1.2 1 0 0 1 1 1 1 zinc-ribbon family SelR PF01641.18 ORY15732.1 - 0.0066 16.5 0.3 0.032 14.3 0.1 1.9 2 0 0 2 2 2 1 SelR domain Dynein_light PF01221.18 ORY15733.1 - 7.9e-41 138.3 2.4 9.2e-41 138.1 2.4 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 RRM_1 PF00076.22 ORY15734.1 - 1.1e-74 246.2 0.8 1.8e-16 59.7 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 ORY15734.1 - 2e-10 40.4 0.0 0.0015 18.4 0.0 5.0 5 0 0 5 5 5 2 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 ORY15734.1 - 6.7e-07 29.2 0.0 1.7 8.7 0.0 4.3 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 ORY15734.1 - 5e-05 23.3 0.0 1.1 9.4 0.0 4.0 3 0 0 3 3 3 2 RNA recognition motif RRM_5 PF13893.6 ORY15734.1 - 0.00023 20.8 0.0 4.4 6.9 0.1 3.5 2 1 1 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 ORY15734.1 - 0.00024 21.1 0.2 0.37 10.9 0.0 4.1 4 0 0 4 4 4 1 Limkain b1 RRM_3 PF08777.11 ORY15734.1 - 0.0056 16.7 0.6 3.5 7.7 0.0 4.3 5 0 0 5 5 5 1 RNA binding motif Smg4_UPF3 PF03467.15 ORY15734.1 - 0.11 12.5 4.1 1.4 8.9 0.5 4.0 3 2 1 4 4 4 0 Smg-4/UPF3 family SET_assoc PF11767.8 ORY15734.1 - 0.15 11.7 0.4 67 3.2 0.0 4.1 5 0 0 5 5 5 0 Histone lysine methyltransferase SET associated TEA PF01285.18 ORY15735.1 - 1.9e-23 82.3 0.1 7.9e-23 80.3 0.1 2.1 1 1 0 1 1 1 1 TEA/ATTS domain dsrm PF00035.26 ORY15736.1 - 0.0087 16.7 0.0 8.4 7.2 0.0 2.7 2 0 0 2 2 2 2 Double-stranded RNA binding motif HMG_box PF00505.19 ORY15737.1 - 2.2e-06 28.0 4.7 2.2e-06 28.0 4.7 2.6 2 1 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 ORY15737.1 - 0.00011 22.7 1.0 0.00039 21.0 1.0 2.0 1 0 0 1 1 1 1 HMG-box domain Amidohydro_1 PF01979.20 ORY15738.1 - 8.6e-76 255.5 0.8 1.7e-75 254.5 0.8 1.4 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.20 ORY15738.1 - 3.5e-55 185.5 2.3 7.5e-55 184.4 2.3 1.6 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_beta PF00699.20 ORY15738.1 - 1.1e-41 140.8 0.4 3.6e-41 139.2 0.1 2.0 2 0 0 2 2 2 1 Urease beta subunit Urease_gamma PF00547.18 ORY15738.1 - 1.1e-38 131.5 0.1 2.8e-38 130.2 0.1 1.7 1 0 0 1 1 1 1 Urease, gamma subunit Amidohydro_3 PF07969.11 ORY15738.1 - 1.7e-08 34.4 0.2 1.9e-06 27.6 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family CN_hydrolase PF00795.22 ORY15741.1 - 4.3e-57 193.4 0.0 4.9e-57 193.2 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase MFS_1 PF07690.16 ORY15743.1 - 9.4e-55 185.9 43.7 8.3e-44 149.9 15.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 ORY15743.1 - 2.1e-07 29.9 19.7 0.00019 20.1 4.4 2.9 2 2 0 2 2 2 2 MFS/sugar transport protein OATP PF03137.20 ORY15743.1 - 0.00021 19.7 0.3 0.0031 15.9 0.7 2.4 2 1 1 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.24 ORY15743.1 - 0.00062 18.7 4.2 0.00062 18.7 4.2 3.1 3 0 0 3 3 3 1 Sugar (and other) transporter MFS_1_like PF12832.7 ORY15743.1 - 0.0025 16.8 2.3 0.0025 16.8 2.3 3.4 2 2 2 4 4 4 1 MFS_1 like family MFS_4 PF06779.14 ORY15743.1 - 0.0046 16.3 16.5 0.028 13.7 8.7 2.9 2 1 1 3 3 3 3 Uncharacterised MFS-type transporter YbfB Erf4 PF10256.9 ORY15745.1 - 0.043 13.9 0.0 6.2 7.0 0.0 2.2 1 1 1 2 2 2 0 Golgin subfamily A member 7/ERF4 family Catalase PF00199.19 ORY15746.1 - 1.5e-170 567.4 0.1 2.1e-170 567.0 0.1 1.2 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 ORY15746.1 - 1.4e-19 70.0 0.0 2.7e-19 69.1 0.0 1.5 1 0 0 1 1 1 1 Catalase-related immune-responsive Catalase_C PF18011.1 ORY15746.1 - 1.1e-10 41.4 2.1 1.8e-10 40.7 1.2 1.8 2 0 0 2 2 2 1 C-terminal domain found in long catalases DJ-1_PfpI PF01965.24 ORY15746.1 - 8.5e-09 35.4 0.1 7.2e-08 32.4 0.0 2.1 1 1 1 2 2 2 1 DJ-1/PfpI family Ribonuc_red_lgN PF00317.21 ORY15746.1 - 0.12 12.4 0.0 0.75 9.8 0.0 2.3 2 0 0 2 2 2 0 Ribonucleotide reductase, all-alpha domain MMM1 PF10296.9 ORY15750.1 - 0.00067 18.8 0.0 0.0046 16.0 0.0 2.1 2 1 0 2 2 2 1 Maintenance of mitochondrial morphology protein 1 SPX PF03105.19 ORY15750.1 - 2.8 7.7 6.3 4.3 7.2 6.3 1.2 1 0 0 1 1 1 0 SPX domain Het-C PF07217.11 ORY15752.1 - 5.5e-253 840.6 0.0 7.1e-253 840.2 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C Zn_dep_PLPC PF00882.18 ORY15752.1 - 0.15 12.0 0.0 0.44 10.5 0.0 1.7 1 0 0 1 1 1 0 Zinc dependent phospholipase C Gly-zipper_Omp PF13488.6 ORY15752.1 - 7.6 6.6 32.9 0.097 12.7 12.8 2.9 2 0 0 2 2 2 0 Glycine zipper AtuA PF07287.11 ORY15753.1 - 2.3e-133 444.3 0.5 2.9e-133 444.0 0.5 1.1 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA DUF1048 PF06304.11 ORY15753.1 - 0.0047 17.4 0.3 0.7 10.4 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1048) Nucleopor_Nup85 PF07575.13 ORY15754.1 - 1.5e-22 80.0 0.0 8.6e-21 74.1 0.0 2.3 1 1 0 1 1 1 1 Nup85 Nucleoporin Nop14 PF04147.12 ORY15754.1 - 0.19 9.9 14.7 0.27 9.4 14.7 1.1 1 0 0 1 1 1 0 Nop14-like family TFIIF_alpha PF05793.12 ORY15754.1 - 0.58 8.7 11.9 0.87 8.1 11.9 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CDC45 PF02724.14 ORY15754.1 - 0.61 8.3 12.7 0.91 7.7 12.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Mpp10 PF04006.12 ORY15754.1 - 0.91 7.9 14.3 1.4 7.3 14.3 1.1 1 0 0 1 1 1 0 Mpp10 protein SDA1 PF05285.12 ORY15754.1 - 1 8.7 14.9 1.6 8.1 14.9 1.1 1 0 0 1 1 1 0 SDA1 Ysc84 PF04366.12 ORY15755.1 - 7.1e-46 155.1 0.1 1.2e-45 154.4 0.1 1.4 1 0 0 1 1 1 1 Las17-binding protein actin regulator RRP7 PF12923.7 ORY15756.1 - 6.2e-31 107.0 7.5 6.2e-31 107.0 7.5 1.8 2 0 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain RRM_Rrp7 PF17799.1 ORY15756.1 - 1.5e-24 86.6 0.0 4.8e-24 85.0 0.0 1.8 1 1 0 1 1 1 1 Rrp7 RRM-like N-terminal domain RRM_1 PF00076.22 ORY15756.1 - 0.0005 19.8 0.0 0.59 10.0 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ABC_tran_CTD PF16326.5 ORY15756.1 - 0.02 15.1 1.7 0.052 13.8 1.7 1.7 1 0 0 1 1 1 0 ABC transporter C-terminal domain FAD_binding_8 PF08022.12 ORY15757.1 - 4.1e-23 81.5 0.0 8.4e-23 80.5 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 ORY15757.1 - 4e-21 75.8 0.0 6.5e-21 75.1 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 ORY15757.1 - 1.1e-19 70.8 9.9 1.1e-19 70.8 9.9 2.3 1 1 1 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.21 ORY15757.1 - 0.11 13.1 0.0 6.5 7.4 0.0 2.3 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain ADH_N PF08240.12 ORY15759.1 - 4.3e-32 110.3 1.0 6.5e-32 109.7 0.1 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORY15759.1 - 4.7e-25 88.1 0.1 1.2e-24 86.8 0.1 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_16 PF10294.9 ORY15759.1 - 8.8e-21 74.4 0.0 6.7e-19 68.3 0.0 2.9 2 1 0 2 2 2 1 Lysine methyltransferase Glu_dehyd_C PF16912.5 ORY15759.1 - 1.4e-08 34.5 0.1 3.3e-08 33.3 0.1 1.6 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus Methyltransf_23 PF13489.6 ORY15759.1 - 2.2e-06 27.6 0.0 1.1e-05 25.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY15759.1 - 4.5e-05 24.1 0.1 0.62 10.8 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain ADH_zinc_N_2 PF13602.6 ORY15759.1 - 0.00052 21.1 0.0 0.0012 19.9 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase MTS PF05175.14 ORY15759.1 - 0.00082 19.0 0.1 1.3 8.6 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase small domain AlaDh_PNT_C PF01262.21 ORY15759.1 - 0.00083 18.7 1.1 0.002 17.5 0.5 1.8 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 ORY15759.1 - 0.0023 17.5 1.4 0.0027 17.3 0.1 1.7 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_11 PF08241.12 ORY15759.1 - 0.0098 16.5 0.0 3.7 8.3 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 ORY15759.1 - 0.013 14.9 0.7 2.6 7.4 0.1 2.2 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Pyr_redox_2 PF07992.14 ORY15759.1 - 0.022 14.0 0.1 0.048 12.9 0.0 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_31 PF13847.6 ORY15759.1 - 0.029 14.2 0.0 8.3 6.2 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain VPS28 PF03997.12 ORY15760.1 - 7.8e-73 244.2 0.3 9.2e-73 244.0 0.3 1.1 1 0 0 1 1 1 1 VPS28 protein C-C_Bond_Lyase PF15617.6 ORY15760.1 - 0.015 14.5 0.1 0.024 13.8 0.1 1.3 1 0 0 1 1 1 0 C-C_Bond_Lyase of the TIM-Barrel fold Phage_lysis PF03245.13 ORY15760.1 - 0.058 13.5 0.1 0.33 11.1 0.0 2.1 2 0 0 2 2 2 0 Bacteriophage Rz lysis protein Phage_TAC_3 PF06896.11 ORY15760.1 - 0.42 11.2 4.3 8.7 7.0 0.2 2.6 2 1 0 2 2 2 0 Phage tail assembly chaperone proteins, TAC Noc2 PF03715.13 ORY15761.1 - 2.8e-127 424.1 0.0 4.7e-127 423.4 0.0 1.4 1 0 0 1 1 1 1 Noc2p family ADH_N PF08240.12 ORY15762.1 - 9.7e-27 93.0 1.5 1.8e-26 92.1 0.2 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORY15762.1 - 3.1e-17 62.8 0.0 4.6e-17 62.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 ORY15762.1 - 2.1e-06 27.4 2.0 0.00017 21.2 0.8 2.4 2 1 0 2 2 2 2 Glucose dehydrogenase C-terminus zf-RING_2 PF13639.6 ORY15763.1 - 2.5e-11 43.7 6.6 2.5e-11 43.7 6.6 1.9 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 ORY15763.1 - 2.7e-09 36.6 2.1 5.5e-09 35.6 2.1 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 ORY15763.1 - 2.8e-07 30.3 6.7 6.2e-07 29.1 6.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORY15763.1 - 2.3e-06 27.4 5.4 4.5e-06 26.4 5.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORY15763.1 - 6.9e-06 25.9 4.4 1.3e-05 25.0 4.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 ORY15763.1 - 0.00017 21.3 2.9 0.00033 20.5 2.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Comm PF15957.5 ORY15763.1 - 0.00023 21.5 0.0 0.00047 20.5 0.0 1.4 1 0 0 1 1 1 1 Commissureless zf-RING_UBOX PF13445.6 ORY15763.1 - 0.00031 20.7 7.0 0.0007 19.6 7.0 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 ORY15763.1 - 0.00034 20.8 7.0 0.0013 18.9 7.0 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 ORY15763.1 - 0.0035 17.4 1.9 0.0096 16.0 1.9 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 ORY15763.1 - 0.0062 16.4 9.3 0.069 13.0 8.7 2.2 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 ORY15763.1 - 0.011 15.5 4.2 0.022 14.5 4.2 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain LapA_dom PF06305.11 ORY15763.1 - 0.11 12.3 0.1 0.23 11.3 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Zn_ribbon_17 PF17120.5 ORY15763.1 - 0.24 11.0 1.4 0.51 10.0 1.4 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type PHD PF00628.29 ORY15763.1 - 0.71 9.8 3.6 1.3 9.0 3.6 1.5 1 0 0 1 1 1 0 PHD-finger zf-P11 PF03854.14 ORY15763.1 - 0.72 9.6 4.8 0.22 11.2 1.3 1.9 2 0 0 2 2 2 0 P-11 zinc finger DUF4083 PF13314.6 ORY15763.1 - 1.2 9.2 6.0 1 9.4 0.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) zf-C3HC4_4 PF15227.6 ORY15763.1 - 1.8 8.8 6.5 4 7.7 6.5 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Ada3 PF10198.9 ORY15764.1 - 1.8e-44 151.1 0.1 1.8e-44 151.1 0.1 1.8 2 0 0 2 2 2 1 Histone acetyltransferases subunit 3 DASH_Spc19 PF08287.11 ORY15764.1 - 0.0054 16.6 8.2 0.0076 16.2 0.1 2.5 2 0 0 2 2 2 1 Spc19 DEC-1_N PF04625.13 ORY15764.1 - 0.97 8.4 8.0 1.5 7.8 6.5 1.8 2 0 0 2 2 2 0 DEC-1 protein, N-terminal region ABC_membrane_2 PF06472.15 ORY15765.1 - 2.2e-91 306.0 0.0 4.6e-91 305.0 0.0 1.5 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 ORY15765.1 - 1.1e-13 51.9 0.0 2.5e-13 50.7 0.0 1.6 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 ORY15765.1 - 0.0076 16.1 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system THOC7 PF05615.13 ORY15765.1 - 0.016 15.5 0.9 0.033 14.5 0.9 1.4 1 0 0 1 1 1 0 Tho complex subunit 7 AAA_23 PF13476.6 ORY15765.1 - 0.017 15.6 0.2 1.4 9.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 ORY15765.1 - 0.049 13.4 0.0 0.17 11.6 0.1 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_16 PF13191.6 ORY15765.1 - 0.081 13.3 0.0 0.21 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain End3 PF12761.7 ORY15765.1 - 0.12 12.5 0.7 0.25 11.5 0.7 1.4 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 DUF4360 PF14273.6 ORY15766.1 - 1.9e-53 181.0 0.1 2.2e-53 180.8 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Aldedh PF00171.22 ORY15767.1 - 3.9e-152 507.0 0.0 4.8e-152 506.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 ORY15767.1 - 0.082 11.9 0.0 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) PAH PF02671.21 ORY15767.1 - 0.16 12.2 0.2 0.6 10.3 0.0 2.1 2 0 0 2 2 2 0 Paired amphipathic helix repeat FRG1 PF06229.12 ORY15768.1 - 4e-54 183.3 0.1 8.7e-54 182.1 0.1 1.6 1 1 0 1 1 1 1 FRG1-like domain Fascin PF06268.13 ORY15768.1 - 2.2e-05 24.6 0.0 0.01 16.1 0.0 2.7 3 0 0 3 3 3 2 Fascin domain 2OG-FeII_Oxy PF03171.20 ORY15769.1 - 0.00015 22.2 0.0 0.00048 20.6 0.0 1.9 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 ORY15769.1 - 0.0048 17.6 0.0 0.0096 16.7 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Acyl_transf_3 PF01757.22 ORY15770.1 - 1.1e-15 57.5 24.9 1.1e-15 57.5 24.9 1.6 1 1 1 2 2 2 1 Acyltransferase family Peptidase_M7 PF02031.16 ORY15771.1 - 0.045 13.9 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 Streptomyces extracellular neutral proteinase (M7) family Reprolysin_3 PF13582.6 ORY15771.1 - 0.064 13.8 0.3 0.29 11.7 0.1 2.0 2 1 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like 2-oxoacid_dh PF00198.23 ORY15794.1 - 1.6e-78 263.4 0.1 2.1e-78 263.0 0.1 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 ORY15794.1 - 3.4e-20 71.6 2.6 6.3e-20 70.8 2.6 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme HlyD_3 PF13437.6 ORY15794.1 - 4.7e-06 27.3 0.6 0.012 16.3 0.0 2.7 2 1 1 3 3 3 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 ORY15794.1 - 0.00015 21.6 0.1 0.11 12.3 0.0 2.4 1 1 1 2 2 2 2 Biotin-lipoyl like GCV_H PF01597.19 ORY15794.1 - 0.061 13.2 0.4 0.14 12.1 0.4 1.6 1 0 0 1 1 1 0 Glycine cleavage H-protein DUF1387 PF07139.11 ORY15794.1 - 0.23 11.2 8.9 0.32 10.7 8.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Presenilin PF01080.17 ORY15794.1 - 1 8.0 10.3 1.5 7.5 10.3 1.1 1 0 0 1 1 1 0 Presenilin Complex1_LYR PF05347.15 ORY15795.1 - 1.8e-08 34.3 0.4 2.3e-08 34.0 0.4 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Histone_H2A_C PF16211.5 ORY15796.1 - 1.4e-21 75.9 2.3 2.5e-21 75.1 2.3 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 ORY15796.1 - 6.9e-17 62.0 0.0 9.1e-17 61.6 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 ORY15796.1 - 1e-05 25.7 0.0 1.4e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 ORY15797.1 - 7.7e-23 81.3 0.4 9.5e-23 81.0 0.4 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 ORY15797.1 - 6.9e-05 23.0 0.9 0.0001 22.5 0.0 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 ORY15797.1 - 0.00026 21.4 0.0 0.00044 20.7 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A DUF1018 PF06252.12 ORY15797.1 - 0.029 15.3 0.4 0.041 14.9 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) RP-C PF03428.13 ORY15797.1 - 0.051 13.2 0.1 0.11 12.2 0.1 1.5 1 1 0 1 1 1 0 Replication protein C N-terminal domain Peptidase_C54 PF03416.19 ORY15798.1 - 4.7e-94 314.9 0.0 6.2e-94 314.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C54 G-patch PF01585.23 ORY15799.1 - 3.2e-09 36.6 1.0 8.8e-09 35.1 1.0 1.9 1 0 0 1 1 1 1 G-patch domain R3H PF01424.22 ORY15799.1 - 4.8e-07 29.7 0.0 1.1e-06 28.6 0.0 1.6 1 0 0 1 1 1 1 R3H domain G-patch_2 PF12656.7 ORY15799.1 - 0.034 14.2 1.0 0.15 12.1 0.5 2.5 2 0 0 2 2 2 0 G-patch domain Chromo PF00385.24 ORY15799.1 - 0.077 12.9 0.0 0.24 11.3 0.0 1.8 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain AAA PF00004.29 ORY15800.1 - 2.5e-37 128.3 0.0 4.9e-37 127.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 ORY15800.1 - 4.4e-09 36.2 0.3 1e-07 31.8 0.0 3.0 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_lid_3 PF17862.1 ORY15800.1 - 1.1e-08 34.7 0.1 4.5e-08 32.8 0.0 2.1 2 0 0 2 2 2 1 AAA+ lid domain RuvB_N PF05496.12 ORY15800.1 - 5.7e-05 22.9 0.0 0.00011 21.9 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 ORY15800.1 - 6.4e-05 23.2 1.4 0.0011 19.2 0.1 3.0 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 ORY15800.1 - 0.00039 20.4 0.1 0.0017 18.4 0.0 2.2 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) DUF815 PF05673.13 ORY15800.1 - 0.00057 19.1 0.0 0.0011 18.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.6 ORY15800.1 - 0.00076 19.9 2.6 0.0041 17.5 0.2 3.1 3 1 0 3 3 3 1 AAA ATPase domain TIP49 PF06068.13 ORY15800.1 - 0.0017 17.7 0.0 0.0032 16.7 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain IstB_IS21 PF01695.17 ORY15800.1 - 0.0028 17.4 0.0 0.0056 16.4 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 ORY15800.1 - 0.0049 16.3 0.1 0.01 15.2 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_2 PF07724.14 ORY15800.1 - 0.007 16.5 0.0 0.013 15.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 ORY15800.1 - 0.034 14.3 0.0 0.081 13.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 ORY15800.1 - 0.04 13.5 0.0 0.18 11.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 ORY15800.1 - 0.043 14.3 0.0 0.16 12.5 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 ORY15800.1 - 0.073 13.1 0.0 0.18 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 ORY15800.1 - 0.15 12.0 0.0 0.34 10.8 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_24 PF13479.6 ORY15800.1 - 0.16 11.6 0.0 0.34 10.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 ORY15800.1 - 0.2 11.1 0.0 0.43 10.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_28 PF13521.6 ORY15800.1 - 0.44 10.8 2.6 0.76 10.0 0.1 2.6 3 0 0 3 3 3 0 AAA domain Mito_carr PF00153.27 ORY15801.1 - 2.5e-63 210.0 1.6 1.7e-22 79.2 0.1 3.5 3 0 0 3 3 3 3 Mitochondrial carrier protein tRNA-synt_2 PF00152.20 ORY15801.1 - 3.8e-62 210.2 0.0 1e-61 208.8 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 ORY15801.1 - 5.5e-09 35.9 0.0 1.1e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Serine_protease PF18405.1 ORY15801.1 - 0.077 12.1 0.1 0.34 10.0 0.0 2.0 1 1 1 2 2 2 0 Gammaproteobacterial serine protease TetR_C_34 PF17929.1 ORY15801.1 - 0.1 12.7 0.0 8.6 6.5 0.0 2.6 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain COX6B PF02297.17 ORY15803.1 - 6.8e-23 80.7 4.5 8.6e-23 80.4 4.5 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb GCK PF07802.11 ORY15803.1 - 0.076 13.4 1.4 0.45 11.0 0.1 2.1 2 0 0 2 2 2 0 GCK domain Pet191_N PF10203.9 ORY15803.1 - 0.3 11.4 2.3 0.71 10.2 0.3 2.0 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 SYS1 PF09801.9 ORY15804.1 - 4.5e-58 195.5 12.2 5.1e-58 195.3 12.2 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network VIT_2 PF13757.6 ORY15805.1 - 0.013 15.4 0.0 0.028 14.3 0.0 1.5 1 0 0 1 1 1 0 Vault protein inter-alpha-trypsin domain TPR_14 PF13428.6 ORY15806.1 - 1.4e-09 38.0 7.7 0.76 10.8 0.0 8.2 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_2 PF07719.17 ORY15806.1 - 1.6e-09 37.2 8.3 0.02 15.0 0.0 8.0 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_19 PF14559.6 ORY15806.1 - 4.3e-07 30.3 4.0 0.93 10.1 0.0 5.8 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 ORY15806.1 - 4.8e-07 29.3 0.8 0.032 14.0 0.0 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 ORY15806.1 - 9e-06 25.3 0.1 0.016 14.9 0.0 2.8 2 0 0 2 2 2 2 TPR repeat TPR_16 PF13432.6 ORY15806.1 - 0.00016 22.3 4.0 0.12 13.0 0.1 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 ORY15806.1 - 0.00066 19.9 0.8 0.94 10.0 0.1 4.4 3 1 1 4 4 4 1 Tetratricopeptide repeat ChAPs PF09295.10 ORY15806.1 - 0.00077 18.6 0.0 0.0019 17.3 0.0 1.6 2 0 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_8 PF13181.6 ORY15806.1 - 0.0084 16.2 6.2 69 4.0 0.0 6.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 ORY15806.1 - 0.011 15.7 8.0 16 5.8 0.0 6.2 6 0 0 6 6 6 0 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY15806.1 - 0.75 10.1 5.9 0.35 11.1 0.1 3.4 3 0 0 3 3 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 ORY15806.1 - 0.76 10.0 7.1 18 5.6 0.1 5.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.6 ORY15806.1 - 2.1 8.7 15.5 19 5.6 0.3 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_4 PF07721.14 ORY15806.1 - 3.5 8.5 9.7 93 4.1 0.1 5.4 5 0 0 5 5 4 0 Tetratricopeptide repeat GRP PF07172.11 ORY15806.1 - 6.7 7.5 7.8 17 6.2 7.8 1.6 1 0 0 1 1 1 0 Glycine rich protein family Peptidase_M3 PF01432.20 ORY15807.1 - 5.4e-104 349.0 0.0 6.1e-104 348.8 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.6 ORY15807.1 - 0.038 13.6 0.0 0.06 13.0 0.0 1.2 1 0 0 1 1 1 0 Peptidase M50B-like ApoO PF09769.9 ORY15808.1 - 1.4e-37 128.5 0.3 2.9e-37 127.6 0.1 1.6 2 0 0 2 2 2 1 Apolipoprotein O DUF1304 PF06993.12 ORY15808.1 - 0.078 13.0 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1304) Med14 PF08638.11 ORY15809.1 - 4.8e-56 189.2 0.1 8.4e-56 188.4 0.1 1.3 1 0 0 1 1 1 1 Mediator complex subunit MED14 ATG22 PF11700.8 ORY15810.1 - 1.4e-199 663.7 13.0 1.6e-199 663.5 13.0 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 ORY15810.1 - 6.8e-06 25.2 18.3 6.8e-06 25.2 18.3 3.2 2 1 1 3 3 3 2 Major Facilitator Superfamily MFS_2 PF13347.6 ORY15810.1 - 0.52 8.8 34.5 2.2 6.7 17.9 2.9 2 1 0 2 2 2 0 MFS/sugar transport protein TBPIP PF07106.13 ORY15811.1 - 5e-14 52.0 0.2 5e-14 52.0 0.2 2.3 3 0 0 3 3 3 1 TBPIP/Hop2 winged helix domain DUF3829 PF12889.7 ORY15811.1 - 0.0037 16.8 1.1 0.0037 16.8 1.1 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3829) YycH PF07435.11 ORY15811.1 - 0.019 14.0 0.2 0.029 13.3 0.2 1.2 1 0 0 1 1 1 0 YycH protein His_Phos_1 PF00300.22 ORY15811.1 - 0.062 13.0 1.2 0.46 10.2 0.5 2.0 1 1 0 2 2 2 0 Histidine phosphatase superfamily (branch 1) TFIIE_beta PF02186.15 ORY15811.1 - 0.077 13.3 0.3 0.31 11.3 0.1 2.1 2 0 0 2 2 2 0 TFIIE beta subunit core domain HTH_IclR PF09339.10 ORY15811.1 - 0.1 12.4 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 IclR helix-turn-helix domain TBCC_N PF16752.5 ORY15811.1 - 0.54 10.7 4.9 6.1 7.3 0.3 2.6 1 1 1 2 2 2 0 Tubulin-specific chaperone C N-terminal domain DUF1104 PF06518.11 ORY15811.1 - 0.71 10.3 5.3 0.34 11.3 0.9 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1104) Sel1 PF08238.12 ORY15812.1 - 7.6e-21 74.1 19.0 9.6e-05 22.9 0.1 7.0 7 0 0 7 7 7 5 Sel1 repeat TPR_1 PF00515.28 ORY15812.1 - 0.09 12.6 3.1 1.2 9.1 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 ORY15812.1 - 2.6 8.4 4.8 36 4.8 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 ORY15812.1 - 6.7 7.8 6.4 64 4.8 0.0 4.1 4 1 1 5 5 5 0 Tetratricopeptide repeat ASF1_hist_chap PF04729.13 ORY15813.1 - 5.6e-73 244.0 0.0 7.2e-73 243.6 0.0 1.1 1 0 0 1 1 1 1 ASF1 like histone chaperone Nop14 PF04147.12 ORY15813.1 - 6.1 4.9 19.3 7.6 4.6 19.3 1.0 1 0 0 1 1 1 0 Nop14-like family TMF_TATA_bd PF12325.8 ORY15814.1 - 0.064 13.5 2.6 0.16 12.2 2.6 1.6 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding FapA PF03961.13 ORY15814.1 - 0.33 9.5 7.2 0.48 9.0 7.2 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Fez1 PF06818.15 ORY15814.1 - 1.5 9.2 6.4 1.3 9.4 4.8 1.6 1 1 0 1 1 1 0 Fez1 Proteasome PF00227.26 ORY15815.1 - 7.5e-47 159.3 0.1 1e-46 158.8 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.8 ORY15815.1 - 2.5e-14 52.4 1.1 2.5e-14 52.4 1.1 1.9 3 0 0 3 3 3 1 Proteasome beta subunits C terminal Actin PF00022.19 ORY15816.1 - 6.8e-142 472.9 0.0 7.6e-142 472.7 0.0 1.0 1 0 0 1 1 1 1 Actin MBOAT PF03062.19 ORY15817.1 - 6.6e-47 160.5 16.1 6.6e-47 160.5 16.1 1.7 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family T4SS_CagC PF16943.5 ORY15817.1 - 0.18 12.0 0.4 0.49 10.6 0.1 1.9 2 0 0 2 2 2 0 Cag pathogenicity island, type IV secretory system Glyco_hydro_17 PF00332.18 ORY15818.1 - 6.3e-06 26.0 0.3 6.9e-05 22.6 0.1 2.3 1 1 0 2 2 2 1 Glycosyl hydrolases family 17 Thioredoxin PF00085.20 ORY15819.1 - 2e-64 214.1 6.3 6.5e-32 109.6 0.1 3.9 5 0 0 5 5 5 3 Thioredoxin Thioredoxin_6 PF13848.6 ORY15819.1 - 1.8e-48 164.9 1.3 2.2e-35 122.2 0.3 3.3 2 1 1 3 3 3 3 Thioredoxin-like domain OST3_OST6 PF04756.13 ORY15819.1 - 3.8e-08 33.0 0.9 0.0091 15.4 0.0 3.1 2 1 1 3 3 3 2 OST3 / OST6 family, transporter family Calsequestrin PF01216.17 ORY15819.1 - 4.5e-08 32.5 0.6 1e-07 31.4 0.6 1.6 1 1 0 1 1 1 1 Calsequestrin Thioredoxin_8 PF13905.6 ORY15819.1 - 7.4e-08 32.6 0.0 0.14 12.5 0.0 4.7 4 1 1 5 5 5 2 Thioredoxin-like Thioredoxin_2 PF13098.6 ORY15819.1 - 2.2e-07 31.3 3.5 0.002 18.5 0.1 3.6 3 1 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 ORY15819.1 - 5.4e-07 29.7 0.1 0.054 13.7 0.0 3.2 3 0 0 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.21 ORY15819.1 - 6.8e-06 26.0 0.2 0.057 13.3 0.1 2.7 2 1 0 2 2 2 2 AhpC/TSA family ERp29_N PF07912.13 ORY15819.1 - 1.8e-05 24.9 0.3 0.52 10.5 0.0 3.8 3 1 0 3 3 3 1 ERp29, N-terminal domain Redoxin PF08534.10 ORY15819.1 - 0.0025 17.5 3.9 0.46 10.2 0.0 3.9 4 0 0 4 4 4 1 Redoxin ApoLp-III PF07464.11 ORY15819.1 - 0.027 14.5 1.8 0.027 14.5 1.8 1.9 2 0 0 2 2 1 0 Apolipophorin-III precursor (apoLp-III) MIS13 PF08202.11 ORY15819.1 - 0.043 13.1 0.0 0.075 12.3 0.0 1.3 1 0 0 1 1 1 0 Mis12-Mtw1 protein family TraF PF13728.6 ORY15819.1 - 0.34 10.7 2.6 6.4 6.5 0.0 3.4 3 1 0 3 3 3 0 F plasmid transfer operon protein Thioredoxin_4 PF13462.6 ORY15819.1 - 6.2 7.0 7.1 12 6.0 0.1 3.7 3 2 0 4 4 4 0 Thioredoxin PhyH PF05721.13 ORY15820.1 - 0.042 14.1 0.0 0.4 10.9 0.0 2.2 2 0 0 2 2 2 0 Phytanoyl-CoA dioxygenase (PhyH) Glyco_hydro_32N PF00251.20 ORY15821.1 - 3.7e-47 161.4 1.8 5.8e-47 160.7 1.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 ORY15821.1 - 2.4e-28 99.1 0.2 4.2e-28 98.3 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal DUF4975 PF16346.5 ORY15821.1 - 2.9e-05 24.2 0.0 5e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4975) BNR_2 PF13088.6 ORY15821.1 - 0.00037 19.9 1.3 0.025 13.9 0.1 2.3 1 1 1 2 2 2 2 BNR repeat-like domain BNR PF02012.20 ORY15821.1 - 0.01 15.7 0.3 0.048 13.7 0.3 2.3 1 0 0 1 1 1 0 BNR/Asp-box repeat zf-rbx1 PF12678.7 ORY15822.1 - 1.6e-09 37.9 4.1 3.6e-09 36.8 4.1 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 ORY15822.1 - 3.8e-08 33.5 4.3 3.8e-08 33.5 4.3 2.1 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 ORY15822.1 - 3e-06 27.0 1.8 7.2e-06 25.8 1.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 ORY15822.1 - 6.6e-05 22.7 4.5 0.00076 19.3 2.0 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORY15822.1 - 8.3e-05 22.5 1.7 0.00021 21.2 1.8 1.6 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 ORY15822.1 - 0.00026 21.0 1.1 0.00056 19.9 1.1 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Zn_ribbon_17 PF17120.5 ORY15822.1 - 0.00051 19.6 1.9 0.001 18.6 1.9 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_2 PF13923.6 ORY15822.1 - 0.00053 19.8 4.4 0.00053 19.8 4.4 1.7 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 ORY15822.1 - 0.0015 18.5 4.2 0.0043 17.1 4.2 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 ORY15822.1 - 0.016 15.1 5.6 0.038 13.9 5.6 1.6 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 ORY15822.1 - 0.14 11.9 3.1 0.11 12.2 0.6 2.0 2 0 0 2 2 2 0 RING-like zinc finger zf-RING-like PF08746.11 ORY15822.1 - 0.52 10.7 3.3 0.97 9.8 3.3 1.4 1 0 0 1 1 1 0 RING-like domain zf-C3HC4_4 PF15227.6 ORY15822.1 - 0.58 10.4 1.7 1.7 8.9 1.7 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 ORY15822.1 - 0.62 9.9 3.3 0.71 9.7 1.4 1.9 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain S36_mt PF10937.8 ORY15823.1 - 0.083 14.5 1.2 0.083 14.5 1.2 2.3 2 0 0 2 2 2 0 Ribosomal protein S36, mitochondrial Prenylcys_lyase PF07156.14 ORY15824.1 - 4.2e-98 328.8 0.0 5.3e-98 328.5 0.0 1.1 1 0 0 1 1 1 1 Prenylcysteine lyase Amino_oxidase PF01593.24 ORY15824.1 - 2.6e-15 56.7 0.0 4.8e-15 55.8 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 ORY15824.1 - 1.3e-13 50.9 0.4 1.1e-12 48.0 0.2 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 ORY15824.1 - 2.6e-09 37.3 0.2 3.4e-05 23.9 0.0 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding DAO PF01266.24 ORY15824.1 - 2.8e-08 33.7 0.2 3.1e-05 23.8 0.6 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ORY15824.1 - 0.00053 19.3 0.3 0.02 14.2 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ORY15824.1 - 0.036 12.8 0.6 4.4 5.9 0.2 2.1 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_3 PF13738.6 ORY15824.1 - 0.037 13.3 0.1 3.4 6.8 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 ORY15824.1 - 0.063 12.5 0.1 0.12 11.6 0.1 1.4 1 0 0 1 1 1 0 Thi4 family Shikimate_DH PF01488.20 ORY15824.1 - 0.083 13.0 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 ORY15824.1 - 0.099 13.2 0.2 8 7.1 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 ORY15824.1 - 0.14 11.8 0.1 0.26 10.9 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA SKG6 PF08693.10 ORY15825.1 - 0.00058 19.2 0.1 0.0012 18.2 0.1 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain RTX PF02382.15 ORY15825.1 - 0.098 12.3 0.4 0.14 11.8 0.4 1.3 1 0 0 1 1 1 0 N-terminal domain in RTX protein zf-H2C2 PF09337.10 ORY15826.1 - 4.1e-16 58.9 1.3 7.6e-16 58.1 1.3 1.5 1 0 0 1 1 1 1 H2C2 zinc finger Integrase_H2C2 PF17921.1 ORY15826.1 - 1.1e-11 44.7 0.3 1.7e-11 44.0 0.3 1.3 1 0 0 1 1 1 1 Integrase zinc binding domain Acetyltransf_1 PF00583.25 ORY15826.1 - 7.2e-05 23.0 0.0 0.00013 22.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 ORY15826.1 - 0.005 17.0 0.0 0.0083 16.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 ORY15826.1 - 0.16 12.7 0.0 0.33 11.6 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain SprT-like PF10263.9 ORY15827.1 - 1.2e-38 131.4 0.3 2.7e-38 130.3 0.3 1.6 1 0 0 1 1 1 1 SprT-like family Zn_ribbon_SprT PF17283.2 ORY15827.1 - 2e-09 37.2 5.6 4.6e-09 36.0 5.6 1.7 1 0 0 1 1 1 1 SprT-like zinc ribbon domain DUF4379 PF14311.6 ORY15827.1 - 0.06 13.7 3.2 0.19 12.1 3.2 1.9 1 0 0 1 1 1 0 Probable Zinc-ribbon domain Zn-ribbon_8 PF09723.10 ORY15827.1 - 0.17 12.0 3.6 0.16 12.1 1.7 1.9 2 0 0 2 2 2 0 Zinc ribbon domain CDC45 PF02724.14 ORY15827.1 - 0.43 8.8 7.2 0.84 7.8 7.2 1.4 1 0 0 1 1 1 0 CDC45-like protein Aconitase PF00330.20 ORY15828.1 - 3.7e-151 504.3 0.0 4.5e-151 504.0 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 ORY15828.1 - 1.7e-43 148.1 0.0 2.8e-43 147.4 0.0 1.3 1 0 0 1 1 1 1 Aconitase C-terminal domain zf-C2H2_jaz PF12171.8 ORY15829.1 - 2.5e-10 40.4 4.2 4.3e-10 39.6 4.2 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ORY15829.1 - 0.00047 20.5 1.1 0.00084 19.6 1.1 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-U1 PF06220.12 ORY15829.1 - 0.005 16.6 0.4 0.0085 15.8 0.4 1.4 1 0 0 1 1 1 1 U1 zinc finger zf-C2H2_4 PF13894.6 ORY15829.1 - 0.014 16.2 0.2 0.033 15.0 0.2 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger zf-3CxxC_2 PF17180.4 ORY15829.1 - 0.037 14.8 0.3 0.037 14.8 0.3 1.6 2 0 0 2 2 2 0 Zinc-binding domain zf-C2H2_2 PF12756.7 ORY15829.1 - 0.061 13.7 0.7 0.12 12.7 0.7 1.5 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Mog1 PF04603.12 ORY15830.1 - 1.9e-38 132.0 0.0 2.4e-38 131.6 0.0 1.1 1 0 0 1 1 1 1 Ran-interacting Mog1 protein Ureidogly_lyase PF04115.12 ORY15831.1 - 4.2e-70 235.3 0.0 5e-70 235.1 0.0 1.0 1 0 0 1 1 1 1 Ureidoglycolate lyase COG5 PF10392.9 ORY15832.1 - 8.3e-42 142.5 0.4 8.3e-42 142.5 0.4 2.5 3 0 0 3 3 3 1 Golgi transport complex subunit 5 ACC_central PF08326.12 ORY15832.1 - 0.11 10.7 0.3 0.36 9.0 0.0 1.9 2 0 0 2 2 2 0 Acetyl-CoA carboxylase, central region mTERF PF02536.14 ORY15832.1 - 0.16 10.9 0.2 3.4 6.5 0.0 2.2 2 0 0 2 2 2 0 mTERF SAM_2 PF07647.17 ORY15833.1 - 2.2e-09 37.3 0.1 4.6e-09 36.3 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 ORY15833.1 - 3.9e-05 24.0 0.3 9e-05 22.8 0.3 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF4508 PF14969.6 ORY15833.1 - 0.13 12.6 0.6 0.33 11.2 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4508) HemN_C PF06969.16 ORY15833.1 - 0.13 12.4 0.3 2.3 8.3 0.1 2.6 2 0 0 2 2 2 0 HemN C-terminal domain Aa_trans PF01490.18 ORY15835.1 - 4.4e-33 114.6 19.1 6.5e-33 114.0 19.1 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein TipE PF16972.5 ORY15835.1 - 0.16 11.1 0.7 0.26 10.5 0.7 1.2 1 0 0 1 1 1 0 Na+ channel auxiliary subunit TipE tRNA-synt_2b PF00587.25 ORY15836.1 - 8.3e-33 113.8 0.1 5.1e-30 104.8 0.0 2.7 3 0 0 3 3 3 2 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 ORY15836.1 - 9.9e-19 67.3 0.3 2.2e-18 66.2 0.3 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.14 ORY15836.1 - 4.4e-14 52.3 0.0 1.1e-13 51.0 0.0 1.8 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.21 ORY15836.1 - 8.4e-08 32.1 0.0 2.2e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 TGS domain Gar1 PF04410.14 ORY15837.1 - 1e-31 109.8 0.0 1.1e-31 109.7 0.0 1.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region CDP-OH_P_transf PF01066.21 ORY15838.1 - 1.6e-12 48.0 1.5 4.6e-12 46.5 0.1 2.3 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Metallopep PF12044.8 ORY15839.1 - 8.5e-168 558.4 0.0 1e-167 558.1 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family Reprolysin_5 PF13688.6 ORY15839.1 - 0.064 13.4 0.3 0.15 12.2 0.3 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 ORY15839.1 - 0.075 12.9 0.1 0.14 12.1 0.1 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Whi5 PF08528.11 ORY15840.1 - 5.9e-09 35.3 0.0 1.1e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Whi5 like MARVEL PF01284.23 ORY15842.1 - 2e-05 24.6 8.8 3.3e-05 23.9 8.8 1.4 1 1 0 1 1 1 1 Membrane-associating domain 7TMR-DISM_7TM PF07695.11 ORY15842.1 - 0.24 11.2 17.2 0.039 13.8 10.0 2.0 2 0 0 2 2 2 0 7TM diverse intracellular signalling Aminotran_1_2 PF00155.21 ORY15843.1 - 3.5e-36 125.1 0.0 4.7e-36 124.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 ORY15843.1 - 0.084 11.4 0.0 0.14 10.7 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Glucan_synthase PF02364.15 ORY15844.1 - 0 1385.9 0.0 0 1385.4 0.0 1.2 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 ORY15844.1 - 1.1e-44 151.9 0.6 4e-44 150.1 0.6 2.0 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Glyco_hydro_72 PF03198.14 ORY15846.1 - 4.4e-134 446.7 4.8 6.4e-134 446.1 4.8 1.2 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 ORY15846.1 - 3.6e-20 72.4 5.4 1e-19 71.0 5.4 1.8 1 0 0 1 1 1 1 X8 domain Cellulase PF00150.18 ORY15846.1 - 0.00026 20.5 0.7 0.00059 19.3 0.7 1.6 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) adh_short PF00106.25 ORY15847.1 - 7.3e-16 58.2 0.0 1.3e-15 57.4 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY15847.1 - 7.1e-14 51.9 0.0 9.4e-14 51.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase RmlD_sub_bind PF04321.17 ORY15847.1 - 0.021 13.9 0.0 0.028 13.5 0.0 1.1 1 0 0 1 1 1 0 RmlD substrate binding domain Gln-synt_C PF00120.24 ORY15848.1 - 6.4e-51 173.4 0.0 2.1e-50 171.7 0.0 1.7 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain Amidohydro_2 PF04909.14 ORY15848.1 - 9.5e-12 45.3 0.0 2.3e-11 44.0 0.0 1.7 1 0 0 1 1 1 1 Amidohydrolase DUF1638 PF07796.11 ORY15848.1 - 0.16 12.0 0.0 2.9 7.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1638) NACHT PF05729.12 ORY15849.1 - 7.1e-06 26.0 0.2 0.017 15.1 0.1 2.6 1 1 1 2 2 2 2 NACHT domain Ank_3 PF13606.6 ORY15849.1 - 0.0068 16.8 0.0 0.57 10.9 0.0 3.6 4 0 0 4 4 4 1 Ankyrin repeat AAA_22 PF13401.6 ORY15849.1 - 0.011 16.0 0.1 7 6.9 0.0 3.0 2 1 0 2 2 2 0 AAA domain LPD39 PF18858.1 ORY15849.1 - 0.038 14.1 0.3 0.14 12.3 0.0 2.0 2 0 0 2 2 2 0 Large polyvalent protein associated domain 39 AAA_16 PF13191.6 ORY15849.1 - 0.045 14.1 0.3 0.82 10.0 0.0 3.1 3 2 0 3 3 3 0 AAA ATPase domain RNA_helicase PF00910.22 ORY15849.1 - 0.053 13.9 0.0 0.15 12.5 0.0 1.8 1 0 0 1 1 1 0 RNA helicase ATPase_2 PF01637.18 ORY15849.1 - 0.22 11.4 0.0 1.1 9.1 0.0 2.0 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea RdRP PF05183.12 ORY15850.1 - 2.1e-170 568.2 0.0 3e-170 567.7 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase DUF724 PF05266.14 ORY15850.1 - 0.19 11.6 0.0 0.39 10.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) CLP_protease PF00574.23 ORY15852.1 - 3.8e-78 261.6 0.0 4.6e-78 261.3 0.0 1.0 1 0 0 1 1 1 1 Clp protease SDH_sah PF01972.16 ORY15852.1 - 0.13 11.2 0.1 0.18 10.8 0.1 1.3 1 0 0 1 1 1 0 Serine dehydrogenase proteinase Clr5 PF14420.6 ORY15852.1 - 0.19 12.0 0.1 0.35 11.1 0.1 1.4 1 0 0 1 1 1 0 Clr5 domain PDH PF02153.17 ORY15853.1 - 0.18 10.8 0.0 0.25 10.3 0.0 1.1 1 0 0 1 1 1 0 Prephenate dehydrogenase Acetyltransf_13 PF13880.6 ORY15855.1 - 1e-30 105.5 0.1 1.9e-30 104.7 0.1 1.5 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.6 ORY15855.1 - 4.3e-13 48.8 0.2 9.4e-13 47.8 0.2 1.6 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Acetyltransf_3 PF13302.7 ORY15856.1 - 6.6e-27 94.9 0.0 8.1e-27 94.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORY15856.1 - 3.1e-11 43.5 0.0 4.4e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 ORY15856.1 - 6.7e-08 32.8 0.0 7.9e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 ORY15856.1 - 3.1e-06 26.9 0.0 6.5e-06 25.9 0.0 1.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain WSC PF01822.19 ORY15859.1 - 8.3e-14 51.6 3.9 1.9e-13 50.4 3.9 1.7 1 0 0 1 1 1 1 WSC domain SKG6 PF08693.10 ORY15859.1 - 4.5e-06 26.0 0.3 1.2e-05 24.6 0.3 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Trp_oprn_chp PF09534.10 ORY15859.1 - 0.00088 19.1 0.3 0.00088 19.1 0.3 1.7 2 0 0 2 2 2 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF4448 PF14610.6 ORY15859.1 - 0.0013 18.5 0.0 0.0019 18.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Podoplanin PF05808.11 ORY15859.1 - 0.047 13.8 0.0 0.09 12.9 0.0 1.5 1 0 0 1 1 1 0 Podoplanin Amnionless PF14828.6 ORY15859.1 - 0.053 12.3 0.0 0.075 11.9 0.0 1.2 1 0 0 1 1 1 0 Amnionless EphA2_TM PF14575.6 ORY15859.1 - 0.1 13.5 0.0 0.19 12.6 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Herpes_gE PF02480.16 ORY15859.1 - 0.13 10.9 1.3 0.77 8.4 0.0 2.1 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E TrbL PF04610.14 ORY15859.1 - 0.14 11.9 1.1 0.21 11.3 0.2 1.7 2 0 0 2 2 2 0 TrbL/VirB6 plasmid conjugal transfer protein DUF3042 PF11240.8 ORY15859.1 - 0.5 10.4 0.1 0.5 10.4 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3042) AAA_23 PF13476.6 ORY15860.1 - 1e-13 52.3 0.5 1.6e-13 51.6 0.1 1.5 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 ORY15860.1 - 1.5e-10 40.9 0.0 2e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 ORY15860.1 - 5.1e-08 33.0 0.0 6.4e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 ORY15860.1 - 9.1e-05 22.1 0.0 0.00019 21.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 ORY15860.1 - 0.00019 21.4 0.1 0.00026 20.9 0.1 1.3 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran PF00005.27 ORY15860.1 - 0.02 15.4 2.1 0.037 14.5 0.4 2.0 1 1 1 2 2 2 0 ABC transporter Ploopntkinase3 PF18751.1 ORY15860.1 - 0.082 12.8 0.2 0.16 11.8 0.0 1.6 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_22 PF13401.6 ORY15860.1 - 0.13 12.5 0.0 0.25 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF2813 PF11398.8 ORY15860.1 - 0.17 11.1 0.0 0.26 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2813) 23ISL PF16620.5 ORY15862.1 - 0.035 14.3 0.1 0.069 13.3 0.1 1.4 1 0 0 1 1 1 0 Unstructured linker between I-set domains 2 and 3 on MYLCK F-box-like PF12937.7 ORY15862.1 - 2.9 7.9 7.5 0.11 12.4 0.9 2.2 3 0 0 3 3 3 0 F-box-like AAA_16 PF13191.6 ORY15864.1 - 0.011 16.2 0.0 0.015 15.7 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain Helo_like_N PF17111.5 ORY15865.1 - 9.2e-10 38.2 2.8 1.3e-09 37.7 2.8 1.2 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins U79_P34 PF03064.16 ORY15865.1 - 0.029 13.7 0.7 0.05 13.0 0.7 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 NIT PF08376.10 ORY15865.1 - 0.036 14.5 0.2 0.07 13.6 0.2 1.5 1 0 0 1 1 1 0 Nitrate and nitrite sensing SesA PF17107.5 ORY15865.1 - 0.058 13.6 1.6 0.54 10.5 0.0 2.2 1 1 1 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases SH3_2 PF07653.17 ORY15865.1 - 0.13 11.9 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain Borrelia_P83 PF05262.11 ORY15865.1 - 0.14 10.6 5.9 0.2 10.1 5.9 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF2985 PF11204.8 ORY15866.1 - 4.7e-22 77.9 3.8 1.1e-21 76.8 3.8 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) Phage_Gp23 PF10669.9 ORY15866.1 - 0.066 13.5 2.2 0.14 12.5 2.2 1.5 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) eIF2A PF08662.11 ORY15868.1 - 2.8e-79 265.5 0.0 2.8e-79 265.5 0.0 2.0 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 ORY15868.1 - 0.00015 22.4 3.0 0.31 12.0 0.4 5.0 3 2 1 4 4 4 1 WD domain, G-beta repeat PD40 PF07676.12 ORY15868.1 - 0.054 13.5 3.6 40 4.3 0.1 4.6 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat ANAPC1 PF12859.7 ORY15870.1 - 2.2e-31 109.1 0.5 2.2e-31 109.1 0.5 2.5 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 1 DUF4201 PF13870.6 ORY15871.1 - 2.5 7.8 10.6 3.6 7.3 0.0 3.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4201) PCMT PF01135.19 ORY15872.1 - 1.4e-67 227.6 0.0 1.6e-67 227.4 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 ORY15872.1 - 2e-07 30.9 0.0 2.7e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY15872.1 - 1.4e-06 28.9 0.0 2.3e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY15872.1 - 6.8e-05 22.8 0.0 9.3e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain GCD14 PF08704.10 ORY15872.1 - 0.00044 20.0 0.0 0.00062 19.5 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_11 PF08241.12 ORY15872.1 - 0.00051 20.6 0.0 0.00086 19.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORY15872.1 - 0.00067 19.1 0.0 0.0009 18.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 ORY15872.1 - 0.0015 18.5 0.0 0.002 18.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ORY15872.1 - 0.0066 16.0 0.0 0.0099 15.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Fibrillarin PF01269.17 ORY15872.1 - 0.016 14.3 0.0 0.024 13.7 0.0 1.2 1 0 0 1 1 1 0 Fibrillarin PrmA PF06325.13 ORY15872.1 - 0.021 14.2 0.0 0.03 13.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) RrnaAD PF00398.20 ORY15872.1 - 0.043 12.9 0.0 0.056 12.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase FtsJ PF01728.19 ORY15872.1 - 0.084 13.0 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase MetW PF07021.12 ORY15872.1 - 0.09 12.4 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_24 PF13578.6 ORY15872.1 - 0.12 13.4 0.1 0.65 11.1 0.0 2.1 1 1 1 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.12 ORY15872.1 - 0.14 12.9 0.0 0.25 12.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.20 ORY15872.1 - 0.24 10.7 0.0 0.29 10.4 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase GTP_EFTU PF00009.27 ORY15873.1 - 1.1e-07 31.6 0.0 5.3e-07 29.4 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain zf-C2H2 PF00096.26 ORY15874.1 - 0.0082 16.5 4.8 0.42 11.2 0.4 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY15874.1 - 0.054 14.4 5.2 3.7 8.7 0.3 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger Cys_Met_Meta_PP PF01053.20 ORY15875.1 - 3.3e-31 108.2 0.0 4.7e-31 107.7 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 ORY15875.1 - 0.021 14.0 0.0 0.052 12.7 0.0 1.6 2 0 0 2 2 2 0 Aminotransferase class I and II Nrap_D4 PF17405.2 ORY15876.1 - 5.1e-64 215.5 0.0 8.6e-64 214.8 0.0 1.3 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap_D5 PF17406.2 ORY15876.1 - 2.4e-54 183.5 0.2 4.8e-54 182.5 0.2 1.5 1 0 0 1 1 1 1 Nrap protein PAP/OAS1-like domain 5 Nrap PF03813.14 ORY15876.1 - 2e-49 167.6 0.0 4.4e-49 166.4 0.0 1.6 1 0 0 1 1 1 1 Nrap protein domain 1 Nrap_D2 PF17403.2 ORY15876.1 - 1.7e-45 154.5 0.0 1.4e-44 151.5 0.0 2.2 2 0 0 2 2 2 1 Nrap protein PAP/OAS-like domain Nrap_D3 PF17404.2 ORY15876.1 - 4.9e-45 153.5 0.4 1.1e-44 152.3 0.1 1.8 2 0 0 2 2 2 1 Nrap protein domain 3 Nrap_D6 PF17407.2 ORY15876.1 - 7.6e-32 110.4 0.0 1.5e-31 109.4 0.0 1.5 1 0 0 1 1 1 1 Nrap protein domain 6 Fungal_trans PF04082.18 ORY15877.1 - 1.5e-19 70.1 0.5 2.3e-19 69.5 0.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.6 ORY15877.1 - 5.1e-05 23.5 8.2 0.00016 21.9 4.0 2.8 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2 PF00096.26 ORY15877.1 - 0.00043 20.6 15.9 0.0097 16.3 1.7 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY15877.1 - 0.0068 17.1 14.2 0.09 13.7 1.1 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORY15877.1 - 0.12 12.8 6.4 3.9 7.9 0.2 2.7 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Abhydrolase_1 PF00561.20 ORY15878.1 - 3.7e-26 92.3 0.1 8.1e-25 87.9 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORY15878.1 - 1.7e-14 54.9 0.1 2.4e-14 54.5 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORY15878.1 - 2.3e-12 46.7 0.0 4.6e-12 45.7 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 ORY15878.1 - 0.011 14.4 0.0 0.22 10.2 0.0 2.0 2 0 0 2 2 2 0 Ndr family Abhydrolase_4 PF08386.10 ORY15878.1 - 0.014 15.5 0.0 0.025 14.7 0.0 1.3 1 0 0 1 1 1 0 TAP-like protein PBCV_basic_adap PF08789.10 ORY15878.1 - 0.015 15.4 0.0 0.042 14.0 0.0 1.7 2 0 0 2 2 2 0 PBCV-specific basic adaptor domain COesterase PF00135.28 ORY15879.1 - 6.7e-68 229.8 0.0 8.2e-68 229.5 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 ORY15879.1 - 1.9e-07 31.1 1.9 5.2e-07 29.7 0.1 2.4 2 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 ORY15879.1 - 0.069 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family CMD PF02627.20 ORY15880.1 - 6.7e-21 74.1 0.0 1.1e-20 73.5 0.0 1.3 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family adh_short PF00106.25 ORY15881.1 - 2.8e-34 118.3 0.0 3.9e-34 117.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY15881.1 - 1.8e-28 99.7 0.0 2.4e-28 99.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY15881.1 - 1.2e-05 25.3 0.1 0.00032 20.7 0.1 2.2 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 ORY15881.1 - 0.0013 18.3 0.0 0.0024 17.4 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Methyltransf_25 PF13649.6 ORY15881.1 - 0.023 15.4 0.0 0.048 14.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain YjeF_N PF03853.15 ORY15881.1 - 0.072 13.0 0.1 0.8 9.6 0.0 2.1 2 0 0 2 2 2 0 YjeF-related protein N-terminus p450 PF00067.22 ORY15882.1 - 4e-64 217.1 0.0 4.8e-64 216.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Phage_Orf51 PF06194.11 ORY15882.1 - 0.12 12.4 0.0 0.49 10.4 0.0 2.1 1 1 1 2 2 2 0 Phage Conserved Open Reading Frame 51 p450 PF00067.22 ORY15884.1 - 6.3e-52 176.9 0.0 6.9e-52 176.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 ORY15885.1 - 6.9e-15 54.7 0.0 8.2e-15 54.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF5053 PF16476.5 ORY15885.1 - 0.031 13.9 0.0 0.33 10.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5053) FAD_binding_3 PF01494.19 ORY15886.1 - 6.5e-41 140.7 0.0 8.6e-41 140.3 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 ORY15886.1 - 0.00012 21.4 0.0 0.0016 17.8 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORY15886.1 - 0.00022 21.4 0.1 0.00072 19.7 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ORY15886.1 - 0.0004 20.1 0.1 0.06 12.9 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 ORY15886.1 - 0.0016 18.4 0.1 0.0055 16.7 0.0 1.8 2 0 0 2 2 2 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 ORY15886.1 - 0.0061 15.7 0.0 0.011 14.8 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Trp_halogenase PF04820.14 ORY15886.1 - 0.0062 15.4 0.2 0.012 14.5 0.0 1.5 2 0 0 2 2 2 1 Tryptophan halogenase Thi4 PF01946.17 ORY15886.1 - 0.017 14.4 0.0 0.031 13.5 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.27 ORY15886.1 - 0.089 13.4 0.0 7.7 7.2 0.0 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Glyco_hydro_61 PF03443.14 ORY15888.1 - 1.3e-57 195.0 0.1 1.6e-57 194.7 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 PH PF00169.29 ORY15889.1 - 0.00014 22.3 0.5 0.00032 21.2 0.0 1.9 2 0 0 2 2 2 1 PH domain Helitron_like_N PF14214.6 ORY15889.1 - 0.11 12.7 0.0 0.22 11.7 0.0 1.6 1 0 0 1 1 1 0 Helitron helicase-like domain at N-terminus TFIIA PF03153.13 ORY15889.1 - 0.64 10.0 13.1 1.7 8.6 13.1 1.9 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ECH_1 PF00378.20 ORY15890.1 - 6.4e-13 48.6 0.0 7.6e-13 48.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ORY15890.1 - 3.7e-05 23.4 0.1 4.2e-05 23.2 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Glyco_transf_25 PF01755.17 ORY15890.1 - 0.15 11.9 0.1 0.19 11.6 0.1 1.1 1 0 0 1 1 1 0 Glycosyltransferase family 25 (LPS biosynthesis protein) QRPTase_C PF01729.19 ORY15892.1 - 1.9e-54 184.0 0.3 2.8e-54 183.4 0.3 1.2 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain Fungal_trans PF04082.18 ORY15892.1 - 2.7e-06 26.6 0.6 4.5e-06 25.9 0.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF1611_N PF17396.2 ORY15892.1 - 0.046 13.9 0.1 1.2 9.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1611_N) Rossmann-like domain QRPTase_N PF02749.16 ORY15892.1 - 0.074 13.1 0.1 0.19 11.8 0.1 1.8 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, N-terminal domain MFS_1 PF07690.16 ORY15893.1 - 5.5e-37 127.5 25.0 5.5e-37 127.5 25.0 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Phage_holin_2_1 PF04971.12 ORY15893.1 - 9.1 6.4 10.0 43 4.2 0.1 3.6 3 0 0 3 3 3 0 Bacteriophage P21 holin S Clathrin PF00637.20 ORY15895.1 - 1.3e-17 64.0 1.2 1.9e-17 63.5 0.3 1.7 2 0 0 2 2 2 1 Region in Clathrin and VPS zf-RING_UBOX PF13445.6 ORY15895.1 - 0.0086 16.1 0.2 0.02 14.9 0.2 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 ORY15895.1 - 0.022 14.7 0.1 0.022 14.7 0.1 1.6 2 0 0 2 2 2 0 zinc-RING finger domain Sar8_2 PF03058.14 ORY15895.1 - 0.042 14.4 0.1 0.091 13.3 0.1 1.5 1 0 0 1 1 1 0 Sar8.2 family zf-rbx1 PF12678.7 ORY15895.1 - 0.053 13.8 0.1 0.13 12.6 0.1 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_11 PF17123.5 ORY15895.1 - 0.055 13.2 0.3 0.13 12.1 0.3 1.6 1 0 0 1 1 1 0 RING-like zinc finger zf-C3HC4_2 PF13923.6 ORY15895.1 - 0.081 12.8 0.2 0.25 11.2 0.0 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORY15895.1 - 0.2 12.1 0.2 0.6 10.5 0.0 1.8 2 0 0 2 2 2 0 Ring finger domain DUF155 PF02582.14 ORY15896.1 - 9e-48 162.7 0.0 1.2e-47 162.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Cupin_3 PF05899.12 ORY15896.1 - 0.096 12.4 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Rhomboid PF01694.22 ORY15897.1 - 1.4e-15 57.6 7.2 1.4e-15 57.6 7.2 1.4 2 0 0 2 2 2 1 Rhomboid family Gaa1 PF04114.14 ORY15898.1 - 9.7e-173 575.7 1.9 1.2e-172 575.4 1.9 1.1 1 0 0 1 1 1 1 Gaa1-like, GPI transamidase component PCI PF01399.27 ORY15899.1 - 5.1e-08 33.4 0.0 1.4e-07 32.0 0.0 1.8 1 0 0 1 1 1 1 PCI domain ANAPC5 PF12862.7 ORY15899.1 - 1.6e-05 24.9 3.5 1.7e-05 24.8 1.2 2.4 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 5 Rpn9_C PF18261.1 ORY15899.1 - 2.3e-05 23.9 0.2 5.2e-05 22.7 0.2 1.6 1 0 0 1 1 1 1 Rpn9 C-terminal helix Glyco_transf_20 PF00982.21 ORY15899.1 - 0.0012 17.6 0.0 0.0019 16.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 TPR_21 PF09976.9 ORY15899.1 - 0.16 11.7 2.7 0.13 12.0 0.9 1.6 1 1 1 2 2 2 0 Tetratricopeptide repeat-like domain TPR_2 PF07719.17 ORY15899.1 - 0.5 10.6 0.0 0.5 10.6 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Epimerase PF01370.21 ORY15900.1 - 8e-15 55.0 0.0 1.4e-14 54.2 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 ORY15900.1 - 1.1e-13 51.3 0.0 1.6e-13 50.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ORY15900.1 - 2.4e-13 50.4 0.0 3.5e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 ORY15900.1 - 7.5e-11 41.6 0.1 1.4e-10 40.7 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 ORY15900.1 - 1.1e-08 34.9 0.1 8.7e-08 31.9 0.0 1.9 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 ORY15900.1 - 3.1e-07 29.8 0.0 5.1e-06 25.8 0.0 2.6 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 ORY15900.1 - 2.7e-05 23.5 0.3 0.011 14.9 0.2 2.8 1 1 1 2 2 2 1 Male sterility protein adh_short PF00106.25 ORY15900.1 - 0.00039 19.9 0.0 0.00084 18.8 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORY15900.1 - 0.0038 17.2 0.0 7.1 6.5 0.0 3.0 3 0 0 3 3 3 2 KR domain DUF2505 PF10698.9 ORY15900.1 - 0.024 14.8 0.0 0.044 13.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2505) adh_short_C2 PF13561.6 ORY15900.1 - 0.044 13.3 0.0 0.099 12.2 0.0 1.7 2 0 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase Acetyltransf_1 PF00583.25 ORY15902.1 - 3.6e-05 24.0 0.0 3.6e-05 24.0 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ORY15902.1 - 4.9e-05 23.3 0.0 5e-05 23.3 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ORY15902.1 - 0.00015 22.2 0.0 0.00015 22.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 ORY15902.1 - 0.015 15.0 0.0 0.015 15.0 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 ORY15902.1 - 0.021 14.9 0.0 0.022 14.8 0.0 1.0 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 ORY15902.1 - 0.11 12.7 0.0 0.12 12.6 0.0 1.1 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase BTB PF00651.31 ORY15904.1 - 0.0063 16.7 0.0 0.0072 16.5 0.0 1.1 1 0 0 1 1 1 1 BTB/POZ domain YccV-like PF08755.11 ORY15905.1 - 2e-28 98.7 0.1 5.2e-28 97.4 0.1 1.7 1 0 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like Transglut_core2 PF13369.6 ORY15905.1 - 1.5e-18 66.8 0.0 3.5e-18 65.7 0.0 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily F-box-like PF12937.7 ORY15905.1 - 1.1e-07 31.7 0.1 2.2e-07 30.6 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY15905.1 - 9.9e-05 22.1 0.0 0.00029 20.6 0.0 1.9 1 1 0 1 1 1 1 F-box domain Elongin_A PF06881.11 ORY15905.1 - 0.0013 19.2 0.0 0.0029 18.1 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A F-box_4 PF15966.5 ORY15905.1 - 0.046 13.6 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 F-box CRAL_TRIO PF00650.20 ORY15906.1 - 1e-24 87.1 0.0 1.6e-24 86.4 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 ORY15906.1 - 1.5e-10 41.1 0.0 4.6e-10 39.5 0.0 1.9 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain I-set PF07679.16 ORY15907.1 - 0.00049 20.1 0.1 1.4 9.0 0.1 3.9 4 0 0 4 4 4 2 Immunoglobulin I-set domain NCE101 PF11654.8 ORY15907.1 - 0.13 12.0 0.5 0.76 9.5 0.0 2.5 3 0 0 3 3 3 0 Non-classical export protein 1 Peptidase_C12 PF01088.21 ORY15908.1 - 4.9e-50 170.2 0.0 7.5e-50 169.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 ORY15908.1 - 0.00014 21.7 0.0 0.00031 20.6 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases Sugar_tr PF00083.24 ORY15909.1 - 3.4e-119 398.7 31.5 4e-119 398.5 31.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY15909.1 - 1.1e-15 57.5 44.1 7.4e-09 35.0 21.7 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily TMEM132D_C PF15706.5 ORY15909.1 - 0.038 13.8 0.9 0.064 13.0 0.0 1.8 2 0 0 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term PDR_assoc PF08370.11 ORY15909.1 - 0.068 12.9 0.8 1.3 8.8 0.1 2.8 2 0 0 2 2 2 0 Plant PDR ABC transporter associated TssN PF17555.2 ORY15909.1 - 6.9 6.0 10.5 0.22 10.9 3.0 2.1 2 0 0 2 2 2 0 Type VI secretion system, TssN DUF3675 PF12428.8 ORY15911.1 - 0.03 14.9 0.8 0.045 14.3 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3675) Polysacc_lyase PF14099.6 ORY15913.1 - 1.2e-44 152.7 4.6 1.4e-44 152.5 4.6 1.0 1 0 0 1 1 1 1 Polysaccharide lyase Rdx PF10262.9 ORY15913.1 - 0.075 13.2 0.3 0.29 11.4 0.1 2.0 2 1 1 3 3 3 0 Rdx family Melibiase_2 PF16499.5 ORY15914.1 - 9.6e-52 175.9 0.1 1.7e-51 175.1 0.1 1.4 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 ORY15914.1 - 3.6e-10 39.8 0.0 6.9e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase_2 PF16499.5 ORY15915.1 - 3.1e-37 128.3 4.6 3.6e-37 128.1 4.6 1.0 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase_2 PF16499.5 ORY15916.1 - 3.2e-56 190.6 5.8 7.8e-56 189.3 5.8 1.6 1 1 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 ORY15916.1 - 4.1e-12 46.0 1.3 1.8e-09 37.5 0.2 3.1 2 1 1 3 3 3 2 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 ORY15916.1 - 5.8e-08 32.1 0.2 1.2e-07 31.1 0.0 1.5 2 0 0 2 2 2 1 Melibiase Melibiase_2_C PF17450.2 ORY15916.1 - 0.053 13.8 0.0 0.21 11.8 0.0 2.0 1 1 0 1 1 1 0 Alpha galactosidase A C-terminal beta sandwich domain Raffinose_syn PF05691.12 ORY15916.1 - 0.13 10.0 0.0 0.19 9.5 0.0 1.1 1 0 0 1 1 1 0 Raffinose synthase or seed imbibition protein Sip1 HA2 PF04408.23 ORY15918.1 - 1.3e-20 73.7 0.2 2.6e-20 72.7 0.2 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 ORY15918.1 - 2.6e-12 46.9 0.0 6.2e-12 45.7 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 ORY15918.1 - 1.5e-10 41.3 0.0 3.3e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 ORY15918.1 - 9.4e-06 25.5 0.0 2.2e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 ORY15918.1 - 7.3e-05 23.1 0.5 0.00021 21.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 ORY15918.1 - 0.0027 18.0 0.0 0.0063 16.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 ORY15918.1 - 0.019 14.3 0.1 0.089 12.1 0.0 2.0 2 0 0 2 2 2 0 KaiC T2SSE PF00437.20 ORY15918.1 - 0.024 13.7 0.0 0.044 12.8 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein SPATA1_C PF15743.5 ORY15918.1 - 0.033 14.3 1.7 0.063 13.3 1.7 1.3 1 0 0 1 1 1 0 Spermatogenesis-associated C-terminus AAA_29 PF13555.6 ORY15918.1 - 0.04 13.7 0.0 0.091 12.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.6 ORY15918.1 - 0.059 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 ORY15918.1 - 0.082 13.3 0.4 0.81 10.0 0.0 2.5 2 1 0 2 2 2 0 AAA ATPase domain DUF4110 PF13422.6 ORY15919.1 - 4.1e-32 110.1 0.2 4.1e-32 110.1 0.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4110) NR_Repeat PF14046.6 ORY15919.1 - 0.086 13.0 0.2 0.31 11.2 0.1 1.9 2 0 0 2 2 2 0 Nuclear receptor repeat Nop14 PF04147.12 ORY15919.1 - 0.8 7.8 7.6 0.89 7.7 7.6 1.1 1 0 0 1 1 1 0 Nop14-like family RRN3 PF05327.11 ORY15919.1 - 0.8 8.2 5.6 0.86 8.1 5.6 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF4611 PF15387.6 ORY15919.1 - 1.1 9.5 8.6 2.6 8.3 8.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) eIF-3c_N PF05470.12 ORY15919.1 - 1.5 7.0 5.1 1.7 6.9 5.1 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus CDC45 PF02724.14 ORY15919.1 - 2.8 6.1 5.6 2.4 6.3 5.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Pox_RNA_Pol_19 PF05320.12 ORY15919.1 - 3 7.8 6.4 5.6 6.9 6.4 1.4 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Sigma70_ner PF04546.13 ORY15919.1 - 6.2 6.7 11.9 5.9 6.7 11.0 1.4 1 1 0 1 1 1 0 Sigma-70, non-essential region CENP-B_dimeris PF09026.10 ORY15919.1 - 8 6.9 15.8 15 6.1 15.8 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain HDOD PF08668.12 ORY15931.1 - 0.03 13.8 0.0 0.62 9.5 0.0 2.0 2 0 0 2 2 2 0 HDOD domain CYTL1 PF15153.6 ORY15931.1 - 0.053 13.5 0.0 0.075 13.0 0.0 1.1 1 0 0 1 1 1 0 Cytokine-like protein 1 NIP_1 PF08995.10 ORY15932.1 - 0.1 13.0 0.1 0.26 11.7 0.1 1.7 1 0 0 1 1 1 0 Necrosis inducing protein-1 2OG-FeII_Oxy_2 PF13532.6 ORY15934.1 - 7e-10 39.4 0.0 7e-08 32.9 0.0 2.3 1 1 1 2 2 2 2 2OG-Fe(II) oxygenase superfamily p450 PF00067.22 ORY15935.1 - 1.8e-29 102.8 0.0 2.4e-29 102.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_127 PF07944.12 ORY15936.1 - 7.4e-20 70.9 0.6 1.2e-18 66.9 0.1 2.3 2 1 0 2 2 2 2 Beta-L-arabinofuranosidase, GH127 Glyco_hydro_88 PF07470.13 ORY15936.1 - 0.0025 17.0 0.0 0.0081 15.3 0.0 1.7 2 0 0 2 2 2 1 Glycosyl Hydrolase Family 88 HET PF06985.11 ORY15938.1 - 8e-26 91.1 0.0 9.1e-26 91.0 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF3471 PF11954.8 ORY15939.1 - 1.3e-07 32.0 0.0 1.7e-07 31.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) Abhydrolase_4 PF08386.10 ORY15940.1 - 3.1e-15 56.1 0.0 6e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.20 ORY15940.1 - 1.5e-11 44.4 0.0 2.2e-09 37.3 0.1 2.7 2 1 1 3 3 3 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ORY15940.1 - 0.0064 15.8 0.0 0.034 13.4 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 zf-4CXXC_R1 PF10497.9 ORY15941.1 - 0.011 16.0 1.9 0.013 15.7 1.9 1.3 1 0 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 zf-C3H2C3 PF17122.5 ORY15941.1 - 1 9.4 8.3 0.52 10.4 0.7 2.5 2 1 0 2 2 2 0 Zinc-finger MMR_HSR1 PF01926.23 ORY15942.1 - 0.065 13.3 0.0 0.42 10.7 0.0 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase Ank_2 PF12796.7 ORY15944.1 - 6.3e-13 49.1 0.2 1.2e-08 35.4 0.1 3.1 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ORY15944.1 - 1.6e-10 40.3 0.2 0.00058 20.1 0.0 4.5 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 ORY15944.1 - 2.1e-07 31.1 0.6 0.0015 18.8 0.0 3.3 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 ORY15944.1 - 1.3e-06 28.5 1.5 0.0028 18.0 0.1 3.7 3 1 1 4 4 4 2 Ankyrin repeat F-box-like PF12937.7 ORY15944.1 - 0.00011 22.1 0.3 0.24 11.3 0.0 2.4 2 0 0 2 2 2 2 F-box-like Ank_4 PF13637.6 ORY15944.1 - 0.00011 22.7 0.2 0.0065 17.0 0.1 2.8 2 1 0 2 2 2 1 Ankyrin repeats (many copies) F-box PF00646.33 ORY15944.1 - 0.011 15.6 0.1 3.7 7.5 0.0 2.3 2 0 0 2 2 2 0 F-box domain PC4 PF02229.16 ORY15945.1 - 1.3e-20 72.8 0.1 1.9e-20 72.2 0.1 1.3 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) Sulf_transp PF04143.14 ORY15946.1 - 0.0052 16.4 2.5 0.0052 16.4 2.5 1.4 2 0 0 2 2 2 1 Sulphur transport adh_short PF00106.25 ORY15947.1 - 2.9e-23 82.3 0.1 1.5e-21 76.8 0.1 2.7 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY15947.1 - 2.6e-14 53.3 0.1 1.5e-10 41.0 0.0 3.1 3 0 0 3 3 3 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY15947.1 - 0.0033 17.4 0.1 0.0067 16.4 0.1 1.5 1 0 0 1 1 1 1 KR domain NAD_binding_8 PF13450.6 ORY15947.1 - 0.021 15.1 0.7 0.079 13.2 0.2 2.2 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.18 ORY15947.1 - 0.044 13.7 0.1 0.085 12.7 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 ORY15947.1 - 0.061 12.6 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain AdoHcyase_NAD PF00670.21 ORY15947.1 - 0.084 12.9 2.6 0.16 12.0 2.6 1.6 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Methyltransf_25 PF13649.6 ORY15947.1 - 0.094 13.4 0.0 0.2 12.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Cys_rich_CPXG PF14255.6 ORY15948.1 - 0.0092 15.9 1.4 1.3 9.0 0.2 2.6 2 0 0 2 2 2 1 Cysteine-rich CPXCG Sigma70_ner PF04546.13 ORY15948.1 - 0.012 15.5 6.9 0.019 14.8 6.9 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region BUD22 PF09073.10 ORY15948.1 - 0.022 14.1 4.8 0.03 13.7 4.8 1.3 1 0 0 1 1 1 0 BUD22 CobT PF06213.12 ORY15948.1 - 0.057 12.8 11.5 0.091 12.1 11.5 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT TFIIA PF03153.13 ORY15948.1 - 0.057 13.4 4.6 0.062 13.3 4.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SDA1 PF05285.12 ORY15948.1 - 0.068 12.6 10.6 0.093 12.1 10.6 1.2 1 0 0 1 1 1 0 SDA1 DNA_pol_phi PF04931.13 ORY15948.1 - 0.083 11.0 17.4 0.11 10.6 17.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi zf-ribbon_3 PF13248.6 ORY15948.1 - 0.23 10.9 0.2 0.23 10.9 0.2 2.1 2 0 0 2 2 2 0 zinc-ribbon domain SGT1 PF07093.11 ORY15948.1 - 0.26 9.7 4.0 0.32 9.4 4.0 1.1 1 0 0 1 1 1 0 SGT1 protein Mpp10 PF04006.12 ORY15948.1 - 0.41 9.0 12.4 0.55 8.6 12.4 1.1 1 0 0 1 1 1 0 Mpp10 protein PI3K_1B_p101 PF10486.9 ORY15948.1 - 0.45 8.2 2.2 0.52 8.0 2.2 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Nop14 PF04147.12 ORY15948.1 - 0.51 8.5 14.8 0.65 8.1 14.8 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 ORY15948.1 - 0.61 8.3 12.7 0.79 7.9 12.7 1.1 1 0 0 1 1 1 0 CDC45-like protein GOLD_2 PF13897.6 ORY15948.1 - 0.61 10.6 2.7 1.2 9.6 2.7 1.6 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking DUF1840 PF08895.11 ORY15948.1 - 2.9 8.3 5.2 5.4 7.4 5.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) FAM176 PF14851.6 ORY15948.1 - 3 7.5 9.0 6.5 6.4 9.0 1.6 1 0 0 1 1 1 0 FAM176 family TRAP_alpha PF03896.16 ORY15948.1 - 3.3 6.9 7.4 4.6 6.4 7.4 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit TFB6 PF17110.5 ORY15948.1 - 3.4 7.4 7.2 5.9 6.6 7.2 1.3 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH zf-RING_2 PF13639.6 ORY15948.1 - 3.6 8.0 9.8 0.33 11.3 5.0 1.8 2 0 0 2 2 1 0 Ring finger domain PTPRCAP PF15713.5 ORY15948.1 - 4.5 7.6 15.3 0.52 10.6 11.1 1.5 2 0 0 2 2 1 0 Protein tyrosine phosphatase receptor type C-associated BSP_II PF05432.11 ORY15948.1 - 5.3 6.6 19.4 9.2 5.9 19.4 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) p450 PF00067.22 ORY15952.1 - 2.4e-72 244.2 0.0 2.8e-72 244.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_4 PF01565.23 ORY15953.1 - 5.1e-08 32.7 0.0 1.5e-06 28.0 0.0 2.4 1 1 0 1 1 1 1 FAD binding domain ALO PF04030.14 ORY15953.1 - 4.4e-06 26.7 0.7 0.098 12.5 0.0 2.3 2 0 0 2 2 2 2 D-arabinono-1,4-lactone oxidase IMS PF00817.20 ORY15956.1 - 2.4e-39 134.7 0.0 4.3e-39 133.9 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family UBM PF14377.6 ORY15956.1 - 4.1e-20 70.5 6.5 4.1e-07 29.2 0.5 4.2 3 0 0 3 3 3 3 Ubiquitin binding region REV1_C PF16727.5 ORY15956.1 - 4.2e-20 71.9 0.0 9e-20 70.9 0.0 1.6 1 0 0 1 1 1 1 DNA repair protein REV1 C-terminal domain IMS_C PF11799.8 ORY15956.1 - 7.1e-12 46.1 0.0 2.4e-11 44.4 0.0 1.9 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain BRCT_2 PF16589.5 ORY15956.1 - 3.5e-09 36.9 0.0 7.3e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 ORY15956.1 - 1.3e-05 25.4 0.0 3.6e-05 24.1 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 ORY15956.1 - 0.00021 21.2 0.0 0.00058 19.8 0.0 1.8 2 0 0 2 2 2 1 twin BRCT domain mCpol PF18182.1 ORY15956.1 - 0.00066 20.0 0.0 0.0014 18.9 0.0 1.5 1 0 0 1 1 1 1 minimal CRISPR polymerase domain IMS_HHH PF11798.8 ORY15956.1 - 0.013 15.8 1.0 0.075 13.4 0.2 2.7 2 0 0 2 2 2 0 IMS family HHH motif NPL PF17800.1 ORY15957.1 - 2.2e-32 111.8 4.1 1.3e-31 109.3 4.1 2.3 1 1 0 1 1 1 1 Nucleoplasmin-like domain FKBP_C PF00254.28 ORY15957.1 - 6.4e-29 100.1 0.1 2.1e-28 98.5 0.0 2.0 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase ODC_AZ PF02100.17 ORY15958.1 - 2.5e-35 120.9 0.5 3.5e-34 117.2 0.5 2.1 1 1 0 1 1 1 1 Ornithine decarboxylase antizyme DEAD_2 PF06733.15 ORY15959.1 - 2.7e-57 193.2 0.1 5.5e-57 192.2 0.1 1.5 1 0 0 1 1 1 1 DEAD_2 HBB PF06777.11 ORY15959.1 - 1.6e-47 161.7 1.6 8.2e-44 149.6 0.3 2.5 2 0 0 2 2 2 2 Helical and beta-bridge domain Helicase_C_2 PF13307.6 ORY15959.1 - 2.5e-43 148.2 0.0 5.5e-43 147.1 0.0 1.6 1 0 0 1 1 1 1 Helicase C-terminal domain ResIII PF04851.15 ORY15959.1 - 0.00047 20.2 0.0 0.025 14.6 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 ORY15959.1 - 0.0049 16.7 0.0 0.58 9.9 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase PhoH PF02562.16 ORY15959.1 - 0.049 13.1 0.0 0.96 8.9 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein zf-RING_2 PF13639.6 ORY15960.1 - 8e-08 32.5 6.4 1.8e-07 31.4 6.4 1.6 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.8 ORY15960.1 - 2.2e-05 24.5 3.3 7.1e-05 22.9 3.3 1.9 1 0 0 1 1 1 1 FANCL C-terminal domain zf-ANAPC11 PF12861.7 ORY15960.1 - 0.00069 19.6 1.3 0.0016 18.5 1.3 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 ORY15960.1 - 0.0031 17.8 4.4 0.0083 16.4 4.4 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 ORY15960.1 - 0.0058 16.5 5.1 0.014 15.3 5.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.7 ORY15960.1 - 0.023 14.8 4.8 0.054 13.6 4.8 1.7 1 0 0 1 1 1 0 RING-variant domain NIT PF08376.10 ORY15960.1 - 0.031 14.7 2.2 0.054 13.9 0.1 2.5 2 0 0 2 2 2 0 Nitrate and nitrite sensing Gcn1_N PF12074.8 ORY15960.1 - 0.038 13.3 6.7 0.7 9.1 0.5 3.5 3 0 0 3 3 3 0 Generalcontrol nonderepressible 1 (Gcn1) N-terminal zf-RING-like PF08746.11 ORY15960.1 - 0.043 14.1 4.5 0.086 13.2 4.5 1.5 1 0 0 1 1 1 0 RING-like domain Zn_ribbon_17 PF17120.5 ORY15960.1 - 0.12 12.0 3.3 0.24 11.0 3.3 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type C1_1 PF00130.22 ORY15960.1 - 0.16 11.9 3.6 0.1 12.5 1.6 1.7 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_9 PF13901.6 ORY15960.1 - 0.22 11.5 1.7 2.5 8.1 1.9 2.4 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon zf-C3HC4_3 PF13920.6 ORY15960.1 - 1.3 9.0 3.1 2.4 8.1 3.1 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 ORY15960.1 - 4.5 7.2 8.7 1.1 9.2 5.1 2.0 2 0 0 2 2 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 ORY15960.1 - 4.7 7.2 5.3 10 6.1 5.3 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-3CxxC PF13695.6 ORY15961.1 - 6.3e-21 74.7 0.1 8.6e-21 74.3 0.1 1.2 1 0 0 1 1 1 1 Zinc-binding domain F-box PF00646.33 ORY15963.1 - 0.00027 20.7 1.0 0.00027 20.7 1.0 2.1 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 ORY15963.1 - 0.0058 16.5 0.9 0.016 15.1 0.9 1.7 1 0 0 1 1 1 1 F-box-like Pkinase PF00069.25 ORY15964.1 - 2.1e-49 168.3 0.1 2.6e-27 95.8 0.0 3.1 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 ORY15964.1 - 2.6e-23 82.7 0.0 1.3e-14 54.2 0.0 2.7 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORY15964.1 - 0.00012 21.0 0.0 0.00019 20.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Pox_ser-thr_kin PF05445.11 ORY15964.1 - 0.0017 17.4 0.0 0.0025 16.8 0.0 1.1 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Haspin_kinase PF12330.8 ORY15964.1 - 0.0024 16.9 0.1 0.0039 16.2 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 ORY15964.1 - 0.0035 17.3 0.2 0.0066 16.4 0.2 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family WSC PF01822.19 ORY15966.1 - 5e-35 119.5 27.8 4e-19 68.6 10.1 3.8 3 1 0 3 3 3 2 WSC domain Yippee-Mis18 PF03226.14 ORY15967.1 - 6.5e-20 71.3 0.0 7.3e-20 71.2 0.0 1.0 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.8 ORY15967.1 - 0.039 14.2 0.2 0.065 13.5 0.0 1.4 2 0 0 2 2 2 0 C-terminal domain of RIG-I MCM PF00493.23 ORY15968.1 - 4.2e-100 333.4 0.0 6.6e-100 332.8 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 ORY15968.1 - 1.3e-38 131.7 1.1 2.5e-38 130.8 1.1 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 ORY15968.1 - 5.1e-29 100.5 3.8 1.2e-28 99.4 3.8 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 ORY15968.1 - 2.9e-15 56.7 0.0 1e-14 54.9 0.0 2.1 1 0 0 1 1 1 1 MCM N-terminal domain AAA_5 PF07728.14 ORY15968.1 - 4.8e-06 26.6 0.0 2.8e-05 24.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 ORY15968.1 - 5.6e-06 25.9 0.0 0.00018 21.0 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 ORY15968.1 - 0.00059 19.7 0.1 0.0024 17.7 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Elf1 PF05129.13 ORY15968.1 - 0.055 13.5 0.3 0.14 12.2 0.3 1.6 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like Sigma54_activat PF00158.26 ORY15968.1 - 0.1 12.3 0.1 2.5 7.8 0.0 2.8 3 0 0 3 3 3 0 Sigma-54 interaction domain DUF1659 PF07872.11 ORY15968.1 - 0.26 11.0 2.0 19 5.0 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1659) AAA_16 PF13191.6 ORY15968.1 - 0.52 10.7 4.2 0.6 10.5 0.0 3.0 2 1 0 3 3 3 0 AAA ATPase domain TBCA PF02970.16 ORY15969.1 - 5.3e-24 84.4 9.8 5.5e-24 84.3 9.2 1.3 1 1 0 1 1 1 1 Tubulin binding cofactor A FapA PF03961.13 ORY15969.1 - 0.00062 18.5 6.7 0.00074 18.2 6.7 1.0 1 0 0 1 1 1 1 Flagellar Assembly Protein A DUF4533 PF15047.6 ORY15969.1 - 0.015 14.9 2.5 0.015 14.9 2.5 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4533) Exonuc_VII_L PF02601.15 ORY15969.1 - 0.062 12.9 3.0 0.067 12.7 3.0 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Tho2 PF11262.8 ORY15969.1 - 0.084 12.1 3.9 0.1 11.8 3.9 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 RFamide_26RFa PF11109.8 ORY15969.1 - 0.087 13.3 1.0 0.17 12.4 1.0 1.5 1 1 0 1 1 1 0 Orexigenic neuropeptide Qrfp/P518 DUF2570 PF10828.8 ORY15969.1 - 0.18 11.6 6.3 0.19 11.6 6.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2570) DUF2408 PF10303.9 ORY15969.1 - 0.23 12.0 3.9 0.26 11.9 3.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) D123 PF07065.14 ORY15969.1 - 0.24 10.5 2.8 0.28 10.3 2.8 1.1 1 0 0 1 1 1 0 D123 Atg14 PF10186.9 ORY15969.1 - 0.28 10.2 6.2 0.37 9.8 6.2 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 COG2 PF06148.11 ORY15969.1 - 0.3 11.2 5.4 0.12 12.5 0.9 2.0 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4407 PF14362.6 ORY15969.1 - 0.36 10.1 7.5 0.41 9.9 7.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) V_ATPase_I PF01496.19 ORY15969.1 - 0.51 8.2 6.6 0.55 8.1 6.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4398 PF14346.6 ORY15969.1 - 0.93 10.2 10.5 3.1 8.5 2.6 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4398) DASH_Spc34 PF08657.10 ORY15969.1 - 1 9.1 8.8 1.3 8.8 8.8 1.1 1 0 0 1 1 1 0 DASH complex subunit Spc34 DUF1910 PF08928.10 ORY15969.1 - 1.5 8.8 6.0 6.7 6.7 6.0 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF1910) TMPIT PF07851.13 ORY15969.1 - 2.7 7.1 7.8 2.8 7.1 6.6 1.5 1 1 1 2 2 2 0 TMPIT-like protein THOC7 PF05615.13 ORY15970.1 - 9.2e-23 81.0 9.2 9.2e-23 81.0 9.2 2.4 1 1 1 2 2 2 1 Tho complex subunit 7 CALCOCO1 PF07888.11 ORY15970.1 - 0.00024 20.1 24.4 0.00033 19.7 24.4 1.1 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like DivIC PF04977.15 ORY15970.1 - 0.0033 17.2 3.8 0.0033 17.2 3.8 3.4 2 1 1 3 3 3 1 Septum formation initiator Peroxin-13_N PF04088.13 ORY15970.1 - 0.28 11.5 2.0 0.46 10.8 1.7 1.7 1 1 0 1 1 1 0 Peroxin 13, N-terminal region Elongin_A PF06881.11 ORY15971.1 - 1.4e-33 115.6 1.9 2.4e-33 114.8 1.9 1.4 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A Cdh1_DBD_1 PF18196.1 ORY15971.1 - 0.052 13.9 1.3 0.13 12.6 1.3 1.6 1 0 0 1 1 1 0 Chromodomain helicase DNA-binding domain 1 TFIIA PF03153.13 ORY15971.1 - 3.3 7.6 9.7 4.4 7.2 9.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ubiquitin PF00240.23 ORY15972.1 - 6.3e-24 83.5 0.0 7.4e-24 83.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 ORY15972.1 - 9.4e-15 54.2 0.0 1.3e-14 53.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 ORY15972.1 - 4.2e-05 23.9 0.0 0.00013 22.3 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 ORY15972.1 - 0.0076 16.2 0.0 0.0085 16.0 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Adeno_PX PF05829.12 ORY15973.1 - 0.07 13.0 0.5 0.28 11.1 0.0 2.0 2 0 0 2 2 2 0 Adenovirus late L2 mu core protein (Protein X) RabGAP-TBC PF00566.18 ORY15979.1 - 4.8e-34 117.9 0.0 8.4e-34 117.1 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Elongin_A PF06881.11 ORY15980.1 - 0.076 13.6 0.0 4.3 7.9 0.0 2.5 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A adh_short PF00106.25 ORY15981.1 - 3.5e-09 36.4 0.1 0.0038 16.7 0.0 2.9 2 2 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 ORY15981.1 - 0.002 17.7 0.6 0.4 10.2 0.3 2.4 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase HET PF06985.11 ORY15982.1 - 3e-09 37.4 8.4 4.8e-08 33.5 2.0 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.16 ORY15983.1 - 1.9e-05 23.8 30.7 9.3e-05 21.5 30.7 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Rubi_NSP_C PF12601.8 ORY15983.1 - 0.13 12.4 0.1 0.34 11.1 0.1 1.6 1 0 0 1 1 1 0 Rubivirus non-structural protein zf-RING_2 PF13639.6 ORY15984.1 - 1.2e-08 35.1 7.5 3.9e-08 33.5 0.7 2.5 3 0 0 3 3 2 1 Ring finger domain zf-rbx1 PF12678.7 ORY15984.1 - 1.7e-08 34.6 1.1 1.5e-07 31.6 0.2 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 ORY15984.1 - 1.1e-06 28.4 3.6 1.5e-05 24.8 0.8 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORY15984.1 - 1.7e-06 27.8 3.8 2.6e-06 27.2 0.8 2.5 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 ORY15984.1 - 8.9e-06 25.3 1.0 0.016 14.9 0.1 2.6 2 0 0 2 2 2 2 RING-like zinc finger zf-ANAPC11 PF12861.7 ORY15984.1 - 0.00014 21.9 0.5 0.00034 20.6 0.1 1.8 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 ORY15984.1 - 0.0012 18.8 5.1 0.0047 16.9 0.3 2.6 2 1 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 ORY15984.1 - 0.0032 17.4 3.7 0.0035 17.2 0.1 2.5 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 ORY15984.1 - 0.011 15.6 5.7 0.042 13.7 0.3 2.9 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 ORY15984.1 - 0.014 15.3 0.1 0.014 15.3 0.1 2.5 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 DUF2946 PF11162.8 ORY15984.1 - 0.045 14.4 0.7 0.13 12.9 0.7 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2946) Glutaredoxin PF00462.24 ORY15984.1 - 0.14 12.4 0.9 0.89 9.8 0.0 2.4 2 0 0 2 2 2 0 Glutaredoxin zf-RING_4 PF14570.6 ORY15984.1 - 0.15 11.9 0.1 0.15 11.9 0.1 2.1 3 0 0 3 3 2 0 RING/Ubox like zinc-binding domain Sarcoglycan_2 PF05510.13 ORY15984.1 - 0.17 10.6 0.0 0.19 10.4 0.0 1.2 1 0 0 1 1 1 0 Sarcoglycan alpha/epsilon FANCL_C PF11793.8 ORY15984.1 - 0.28 11.4 5.4 3.9 7.7 3.7 2.9 2 1 1 3 3 3 0 FANCL C-terminal domain Zf_RING PF16744.5 ORY15984.1 - 3.4 7.9 8.1 10 6.3 0.1 3.2 3 1 1 4 4 4 0 KIAA1045 RING finger Zn_ribbon_17 PF17120.5 ORY15984.1 - 4.1 7.1 8.9 0.21 11.2 1.3 2.6 3 1 0 3 3 3 0 Zinc-ribbon, C4HC2 type E1-E2_ATPase PF00122.20 ORY15986.1 - 1.7e-35 122.2 18.5 2.8e-30 105.2 0.0 3.7 4 1 1 5 5 5 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 ORY15986.1 - 2.1e-22 79.7 9.8 2.1e-22 79.7 9.8 2.3 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 ORY15986.1 - 1.1e-16 61.8 0.0 3.9e-15 56.7 0.0 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 ORY15986.1 - 1.4e-15 57.1 0.0 2.7e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 ORY15986.1 - 4.4e-14 51.9 0.1 2.3e-13 49.6 0.0 2.2 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 ORY15986.1 - 7e-05 22.7 0.2 0.0014 18.4 0.3 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase PalH PF08733.10 ORY15986.1 - 9.8 5.1 14.7 0.14 11.2 7.3 1.6 2 0 0 2 2 2 0 PalH/RIM21 NACHT PF05729.12 ORY15989.1 - 1.4e-07 31.6 0.0 4.2e-07 30.0 0.0 1.8 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 ORY15989.1 - 0.00019 21.9 1.0 0.00034 21.0 0.1 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 ORY15989.1 - 0.15 12.3 0.1 1.1 9.5 0.0 2.5 3 0 0 3 3 3 0 AAA domain ApbA_C PF08546.11 ORY15997.1 - 1.7e-27 96.1 0.2 3.3e-27 95.2 0.2 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 ORY15997.1 - 2.1e-25 89.2 0.0 3e-25 88.6 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Nif11 PF07862.11 ORY15997.1 - 0.088 13.1 0.5 2.2 8.7 0.0 2.5 2 0 0 2 2 2 0 Nif11 domain Glyco_hydro_6 PF01341.17 ORY15999.1 - 7.7e-103 344.4 0.2 9.9e-103 344.0 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 CBM_1 PF00734.18 ORY15999.1 - 2.2e-13 49.9 7.6 8.4e-13 48.0 7.6 2.1 1 0 0 1 1 1 1 Fungal cellulose binding domain GH131_N PF18271.1 ORY16000.1 - 2.1e-63 214.4 4.1 2.7e-63 214.1 4.1 1.1 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain CBM_1 PF00734.18 ORY16000.1 - 8.1e-12 44.9 9.7 2e-11 43.6 9.7 1.7 1 0 0 1 1 1 1 Fungal cellulose binding domain Otopetrin PF03189.13 ORY16002.1 - 0.038 12.8 5.3 0.073 11.9 5.3 1.4 1 0 0 1 1 1 0 Otopetrin DUF3772 PF12607.8 ORY16003.1 - 0.5 10.2 2.2 18 5.2 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3772) Cofilin_ADF PF00241.20 ORY16004.1 - 1.5e-25 89.4 0.5 1.7e-25 89.1 0.5 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein DDHD PF02862.17 ORY16005.1 - 4.7e-58 197.0 6.5 8e-58 196.2 0.0 3.2 3 1 0 3 3 3 1 DDHD domain RNase_3_N PF18497.1 ORY16005.1 - 0.023 14.9 0.0 0.051 13.8 0.0 1.5 1 0 0 1 1 1 0 Ribonuclease III N-terminal domain DUF676 PF05057.14 ORY16005.1 - 0.23 11.0 0.1 0.53 9.7 0.0 1.6 2 0 0 2 2 2 0 Putative serine esterase (DUF676) Glyco_hydro_31 PF01055.26 ORY16006.1 - 1.6e-131 439.6 5.8 2.2e-131 439.1 5.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 ORY16006.1 - 1.4e-27 96.2 0.0 3.4e-27 94.9 0.0 1.6 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase GHL15 PF14885.6 ORY16006.1 - 0.0027 17.7 1.7 0.02 14.9 0.8 2.2 2 0 0 2 2 2 1 Hypothetical glycosyl hydrolase family 15 Plug_translocon PF10559.9 ORY16006.1 - 3.5 7.5 5.0 19 5.2 0.1 3.8 4 0 0 4 4 4 0 Plug domain of Sec61p Tannase PF07519.11 ORY16007.1 - 2.2e-55 188.5 0.0 2.7e-55 188.2 0.0 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Hydrophobin_2 PF06766.11 ORY16008.1 - 1.6e-23 82.4 12.6 2.1e-23 82.1 12.6 1.1 1 0 0 1 1 1 1 Fungal hydrophobin AA_permease PF00324.21 ORY16009.1 - 4.4e-139 464.2 43.7 5e-139 464.0 43.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ORY16009.1 - 1.3e-30 106.6 49.7 1.7e-30 106.2 49.7 1.1 1 0 0 1 1 1 1 Amino acid permease DUF3671 PF12420.8 ORY16009.1 - 3.5 7.7 5.2 1.1 9.4 0.6 2.5 2 1 0 2 2 2 0 Protein of unknown function Afaf PF15339.6 ORY16011.1 - 0.14 11.9 0.0 0.18 11.5 0.0 1.1 1 0 0 1 1 1 0 Acrosome formation-associated factor Mg_trans_NIPA PF05653.14 ORY16012.1 - 1.8e-92 309.6 29.8 2.3e-92 309.2 29.8 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 ORY16012.1 - 4.9e-05 23.5 5.9 4.9e-05 23.5 5.9 3.3 3 0 0 3 3 3 2 EamA-like transporter family Glyco_hydro_125 PF06824.11 ORY16013.1 - 9.4e-168 558.4 0.0 1.3e-167 557.9 0.0 1.2 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) COG4 PF08318.12 ORY16013.1 - 2.2e-124 414.9 0.0 3.1e-124 414.4 0.0 1.2 1 0 0 1 1 1 1 COG4 transport protein ADIP PF11559.8 ORY16013.1 - 0.06 13.4 1.0 16 5.6 0.3 2.7 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding Ank_2 PF12796.7 ORY16015.1 - 4.8e-29 100.8 0.0 1.1e-07 32.3 0.0 6.8 3 2 4 7 7 6 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY16015.1 - 1.5e-24 86.0 0.1 3.6e-05 24.2 0.0 8.1 7 1 1 8 8 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY16015.1 - 3.8e-18 63.7 0.1 0.45 11.2 0.0 10.4 10 0 0 10 10 10 2 Ankyrin repeat Ank PF00023.30 ORY16015.1 - 5.2e-13 48.8 0.3 2.8 8.6 0.0 9.4 9 1 0 9 9 8 2 Ankyrin repeat Ank_5 PF13857.6 ORY16015.1 - 1.5e-12 47.5 1.1 4.4e-06 26.9 0.0 6.3 5 0 0 5 5 5 2 Ankyrin repeats (many copies) AAA_16 PF13191.6 ORY16015.1 - 2.1e-06 28.3 0.0 1.2e-05 25.7 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 ORY16015.1 - 1.5e-05 25.3 0.0 5.1e-05 23.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain Cutinase PF01083.22 ORY16015.1 - 7.4e-05 22.8 0.0 0.0048 16.9 0.0 2.4 2 0 0 2 2 2 1 Cutinase NACHT PF05729.12 ORY16015.1 - 0.00025 21.0 0.0 0.0007 19.6 0.0 1.8 1 0 0 1 1 1 1 NACHT domain PGAP1 PF07819.13 ORY16015.1 - 0.00035 20.4 0.0 0.0007 19.4 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 ORY16015.1 - 0.00055 20.6 0.0 0.0013 19.3 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family NB-ARC PF00931.22 ORY16015.1 - 0.0026 17.0 0.0 0.0054 16.0 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain RNA_helicase PF00910.22 ORY16015.1 - 0.005 17.2 0.0 0.014 15.8 0.0 1.8 1 0 0 1 1 1 1 RNA helicase AAA PF00004.29 ORY16015.1 - 0.0052 17.2 0.2 0.025 15.0 0.2 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 ORY16015.1 - 0.012 15.6 0.0 0.04 14.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 ORY16015.1 - 0.016 15.8 0.0 0.052 14.1 0.0 1.9 1 0 0 1 1 1 0 ABC transporter AAA_18 PF13238.6 ORY16015.1 - 0.018 15.6 0.1 0.09 13.3 0.0 2.3 2 0 0 2 2 1 0 AAA domain ATPase_2 PF01637.18 ORY16015.1 - 0.019 14.9 0.0 0.053 13.4 0.0 1.7 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea DUF900 PF05990.12 ORY16015.1 - 0.02 14.4 0.0 0.037 13.5 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Ploopntkinase3 PF18751.1 ORY16015.1 - 0.02 14.8 0.0 0.037 13.9 0.0 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 AAA_33 PF13671.6 ORY16015.1 - 0.023 14.9 0.0 0.058 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF676 PF05057.14 ORY16015.1 - 0.025 14.1 0.0 0.049 13.1 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Viral_helicase1 PF01443.18 ORY16015.1 - 0.029 14.1 0.0 0.062 13.0 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 ORY16015.1 - 0.032 14.5 0.0 0.16 12.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 ORY16015.1 - 0.067 12.9 0.1 0.44 10.3 0.0 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain Rad17 PF03215.15 ORY16015.1 - 0.076 12.9 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain Hydrolase_4 PF12146.8 ORY16015.1 - 0.12 11.6 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Yip1 PF04893.17 ORY16016.1 - 0.0026 17.5 5.7 0.0043 16.8 5.7 1.3 1 0 0 1 1 1 1 Yip1 domain DUF456 PF04306.13 ORY16016.1 - 0.0081 16.5 4.2 0.013 15.8 4.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF456) zf-MYST PF17772.1 ORY16016.1 - 0.023 14.3 0.1 0.049 13.2 0.1 1.5 1 0 0 1 1 1 0 MYST family zinc finger domain UCR_UQCRX_QCR9 PF05365.12 ORY16016.1 - 0.052 13.5 0.2 0.13 12.3 0.2 1.7 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like DHHC PF01529.20 ORY16016.1 - 2.6 8.2 5.6 4.7 7.3 5.6 1.3 1 0 0 1 1 1 0 DHHC palmitoyltransferase 2TM PF13239.6 ORY16016.1 - 9.4 6.6 11.3 74 3.7 11.2 2.2 1 1 0 1 1 1 0 2TM domain Amino_oxidase PF01593.24 ORY16017.1 - 5.1e-41 141.4 0.0 6.3e-41 141.1 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 ORY16017.1 - 1.4e-05 25.2 0.0 3.8e-05 23.8 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 ORY16017.1 - 0.015 14.5 0.0 0.025 13.8 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.14 ORY16017.1 - 0.047 12.9 0.0 0.088 12.0 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Ribonuc_L-PSP PF01042.21 ORY16018.1 - 2.5e-31 108.2 0.0 3.3e-31 107.8 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP DUF4360 PF14273.6 ORY16019.1 - 7.3e-21 74.8 2.0 1.1e-20 74.2 2.0 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4360) NPCBM_assoc PF10633.9 ORY16019.1 - 0.028 14.7 0.5 0.11 12.7 0.4 2.0 1 1 0 1 1 1 0 NPCBM-associated, NEW3 domain of alpha-galactosidase DWNN PF08783.11 ORY16020.1 - 1.3e-27 95.9 0.0 2.3e-27 95.1 0.0 1.4 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.6 ORY16020.1 - 3.5e-09 36.3 5.8 6.6e-09 35.4 5.8 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-C3HC4_2 PF13923.6 ORY16020.1 - 0.00073 19.3 8.4 0.0016 18.2 8.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) U-box PF04564.15 ORY16020.1 - 0.0014 18.7 0.0 0.0042 17.2 0.0 1.8 1 0 0 1 1 1 1 U-box domain zf-CCHC PF00098.23 ORY16020.1 - 0.0035 17.4 0.8 0.0035 17.4 0.8 1.8 2 0 0 2 2 1 1 Zinc knuckle zf-RING_2 PF13639.6 ORY16020.1 - 0.017 15.4 6.6 0.035 14.4 6.6 1.5 1 0 0 1 1 1 0 Ring finger domain zf-RING_4 PF14570.6 ORY16020.1 - 0.021 14.6 4.7 0.045 13.6 4.7 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.6 ORY16020.1 - 0.027 14.5 4.9 0.053 13.6 4.9 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-CCHC_5 PF14787.6 ORY16020.1 - 0.054 13.2 1.1 0.13 12.0 1.1 1.6 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-C3HC4_4 PF15227.6 ORY16020.1 - 0.15 12.2 7.6 0.37 11.0 7.6 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 ORY16020.1 - 0.33 10.9 8.3 0.75 9.7 8.3 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.8 ORY16020.1 - 0.38 10.6 3.7 0.88 9.4 3.7 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_3 PF13920.6 ORY16020.1 - 1.1 9.2 11.3 0.096 12.6 5.0 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_9 PF14369.6 ORY16020.1 - 1.8 8.9 7.4 1.7 8.9 0.8 2.8 2 0 0 2 2 2 0 zinc-ribbon HypA PF01155.19 ORY16020.1 - 2 8.5 4.5 8.2 6.5 2.5 2.3 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA ZapB PF06005.12 ORY16020.1 - 6.2 7.3 5.9 2.5 8.6 0.6 2.3 2 0 0 2 2 2 0 Cell division protein ZapB DUF1272 PF06906.11 ORY16020.1 - 6.9 6.8 9.9 0.22 11.6 3.8 1.7 2 0 0 2 2 1 0 Protein of unknown function (DUF1272) Peptidase_S64 PF08192.11 ORY16020.1 - 7.7 4.9 7.1 12 4.3 7.1 1.2 1 0 0 1 1 1 0 Peptidase family S64 RRM_1 PF00076.22 ORY16021.1 - 4.7e-33 112.8 0.1 5.1e-16 58.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 ORY16021.1 - 1.2e-10 41.4 0.1 0.00096 19.2 0.0 2.9 2 0 0 2 2 2 2 RNA recognition motif RRM_3 PF08777.11 ORY16021.1 - 0.0019 18.2 0.0 1.6 8.8 0.0 2.6 2 0 0 2 2 2 2 RNA binding motif Nup35_RRM_2 PF14605.6 ORY16021.1 - 0.016 15.2 0.0 4.9 7.2 0.0 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif TFIIA PF03153.13 ORY16021.1 - 0.22 11.5 24.8 0.3 11.0 24.8 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit HCNGP PF07818.13 ORY16021.1 - 0.9 10.2 4.9 14 6.4 4.9 2.6 1 1 0 1 1 1 0 HCNGP-like protein Spike_torovirin PF17072.5 ORY16022.1 - 0.19 8.8 0.0 0.22 8.6 0.0 1.0 1 0 0 1 1 1 0 Torovirinae spike glycoprotein RabGAP-TBC PF00566.18 ORY16023.1 - 2.5e-51 174.4 0.0 2.6e-49 167.8 0.0 2.1 2 0 0 2 2 2 2 Rab-GTPase-TBC domain Cyclase PF04199.13 ORY16024.1 - 6e-15 55.7 0.0 7.9e-15 55.3 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase Bee_toxin PF17454.2 ORY16025.1 - 1.3 9.2 7.3 0.88 9.6 0.2 2.8 3 0 0 3 3 3 0 Honey bee toxin DUF3052 PF11253.8 ORY16026.1 - 0.1 12.5 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3052) Ammonium_transp PF00909.21 ORY16028.1 - 2.7e-114 382.0 27.2 3.1e-114 381.8 27.2 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Ank_2 PF12796.7 ORY16032.1 - 7.5e-09 36.1 0.0 0.047 14.3 0.0 3.7 4 0 0 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ORY16032.1 - 0.00054 20.2 1.5 5.8 7.8 0.0 4.4 5 0 0 5 5 5 2 Ankyrin repeat Ank_4 PF13637.6 ORY16032.1 - 0.003 18.1 0.1 0.86 10.3 0.0 3.8 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 ORY16032.1 - 0.008 16.5 0.1 2.4 8.6 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 ORY16032.1 - 0.037 14.5 0.2 25 5.6 0.0 3.8 4 0 0 4 4 4 0 Ankyrin repeat CAP_N PF01213.19 ORY16032.1 - 0.14 11.7 0.6 2.4 7.5 2.4 2.0 2 1 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Glyco_hydro_cc PF11790.8 ORY16033.1 - 2.5e-72 243.3 0.2 3.1e-72 243.0 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core EF1G PF00647.19 ORY16033.1 - 0.34 11.0 3.0 0.26 11.3 0.3 1.9 2 0 0 2 2 2 0 Elongation factor 1 gamma, conserved domain TRP PF06011.12 ORY16034.1 - 2.2e-143 478.1 17.7 2.9e-143 477.7 17.7 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 ORY16034.1 - 1.9e-39 135.2 0.5 3.2e-39 134.5 0.5 1.4 1 0 0 1 1 1 1 ML-like domain EphA2_TM PF14575.6 ORY16034.1 - 2.2 9.2 0.0 2.2 9.2 0.0 3.3 4 0 0 4 4 4 0 Ephrin type-A receptor 2 transmembrane domain Fez1 PF06818.15 ORY16037.1 - 5.6 7.4 85.8 1.7 9.1 14.9 4.4 1 1 4 5 5 5 0 Fez1 OST3_OST6 PF04756.13 ORY16038.1 - 2.5e-107 358.6 0.0 3.3e-107 358.2 0.0 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family HXXEE PF13787.6 ORY16038.1 - 0.019 15.7 1.4 0.029 15.2 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function with HXXEE motif CPBP PF02517.16 ORY16038.1 - 3.3 8.1 5.9 11 6.4 5.9 2.1 1 1 0 1 1 1 0 CPBP intramembrane metalloprotease QCR10 PF09796.9 ORY16038.1 - 6.5 6.9 7.4 5.5 7.1 0.4 3.4 2 1 1 3 3 3 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) Band_7 PF01145.25 ORY16039.1 - 3.2e-30 105.5 2.1 5.7e-30 104.6 2.1 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 ORY16039.1 - 0.0036 17.0 0.2 0.0061 16.3 0.2 1.4 1 0 0 1 1 1 1 SPFH domain-Band 7 family Mito_carr PF00153.27 ORY16040.1 - 4.1e-73 241.4 3.5 7.4e-24 83.5 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 ORY16040.1 - 0.00011 21.5 0.5 0.034 13.3 0.1 3.3 2 1 1 3 3 3 2 Gammaproteobacterial serine protease PT-VENN PF04829.13 ORY16040.1 - 0.45 10.6 2.9 11 6.2 0.1 2.6 2 0 0 2 2 2 0 Pre-toxin domain with VENN motif FtsJ PF01728.19 ORY16041.1 - 2.4e-54 184.1 0.0 3.2e-54 183.7 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.6 ORY16041.1 - 0.13 12.0 0.0 0.27 11.1 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain DUF3824 PF12868.7 ORY16044.1 - 2.9e-25 89.7 32.5 2.9e-25 89.7 32.5 9.0 3 2 6 9 9 9 3 Domain of unknwon function (DUF3824) ABA_WDS PF02496.16 ORY16044.1 - 0.001 19.5 23.8 0.091 13.2 2.3 4.7 4 0 0 4 4 4 3 ABA/WDS induced protein DUF1294 PF06961.13 ORY16044.1 - 5.8 7.2 7.4 25 5.2 0.7 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1294) Acyl_transf_3 PF01757.22 ORY16045.1 - 2.9e-21 75.9 23.8 5.2e-21 75.1 23.9 1.4 1 1 0 1 1 1 1 Acyltransferase family adh_short_C2 PF13561.6 ORY16046.1 - 3.2e-39 134.9 0.0 4.4e-39 134.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY16046.1 - 1.5e-35 122.4 0.0 2e-35 122.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORY16046.1 - 1.6e-08 34.7 0.0 2.4e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 KR domain FAD_binding_4 PF01565.23 ORY16065.1 - 3.9e-19 68.8 1.1 6.1e-19 68.1 0.7 1.5 1 1 0 1 1 1 1 FAD binding domain BBE PF08031.12 ORY16065.1 - 1.9e-10 40.6 0.0 4.1e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like TENA_THI-4 PF03070.16 ORY16067.1 - 0.004 17.0 0.1 0.092 12.5 0.0 2.2 2 0 0 2 2 2 2 TENA/THI-4/PQQC family LcrR PF09621.10 ORY16068.1 - 0.1 12.1 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Type III secretion system regulator (LcrR) UQ_con PF00179.26 ORY16069.1 - 2e-37 128.0 0.0 2.6e-37 127.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Pes-10 PF07149.11 ORY16069.1 - 8.8 5.3 11.0 11 5.0 11.0 1.1 1 0 0 1 1 1 0 Pes-10 tRNA-synt_1b PF00579.25 ORY16070.1 - 4e-76 256.1 0.0 5.4e-76 255.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) BAR PF03114.18 ORY16071.1 - 5.3e-62 209.6 5.0 6.5e-62 209.3 5.0 1.1 1 0 0 1 1 1 1 BAR domain FliD_N PF02465.18 ORY16071.1 - 2.3 9.0 7.9 2.2 9.0 0.4 2.8 3 1 0 3 3 3 0 Flagellar hook-associated protein 2 N-terminus PNRC PF15365.6 ORY16072.1 - 6.1e-09 35.4 5.5 6.1e-09 35.4 5.5 5.5 5 0 0 5 5 5 1 Proline-rich nuclear receptor coactivator motif FtsH_ext PF06480.15 ORY16072.1 - 0.72 10.2 2.8 0.72 10.2 0.4 2.2 2 0 0 2 2 2 0 FtsH Extracellular zf-rbx1 PF12678.7 ORY16073.1 - 3e-25 88.3 13.1 4.3e-25 87.7 13.1 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 ORY16073.1 - 4e-17 62.1 10.0 5.2e-17 61.7 10.0 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 ORY16073.1 - 2.5e-06 27.7 14.6 9e-05 22.7 14.6 2.2 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 ORY16073.1 - 0.0016 18.3 11.9 0.027 14.4 11.9 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 ORY16073.1 - 0.0031 17.3 14.7 0.0046 16.8 9.2 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 ORY16073.1 - 0.18 11.7 10.8 0.51 10.2 4.5 2.6 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 ORY16073.1 - 0.33 10.7 15.8 27 4.6 15.8 2.4 1 1 0 1 1 1 0 RING-like zinc finger zf-RING_UBOX PF13445.6 ORY16073.1 - 0.52 10.4 7.8 1.8 8.6 7.8 2.0 1 1 0 1 1 1 0 RING-type zinc-finger FANCL_C PF11793.8 ORY16073.1 - 0.57 10.4 9.3 3 8.1 9.5 1.9 1 1 1 2 2 2 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 ORY16073.1 - 0.69 9.6 14.9 0.14 11.8 4.7 2.2 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type SPC12 PF06645.13 ORY16074.1 - 5.6e-29 100.0 0.1 7.3e-29 99.7 0.1 1.2 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) DUF3040 PF11239.8 ORY16074.1 - 0.081 13.2 0.2 0.099 12.9 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) CorA PF01544.18 ORY16075.1 - 3.1e-44 151.5 0.0 4.2e-44 151.0 0.0 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF2299 PF10061.9 ORY16075.1 - 0.051 13.3 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2299) Ank_2 PF12796.7 ORY16076.1 - 2.7e-23 82.3 2.6 1.4e-11 44.8 0.1 4.8 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ORY16076.1 - 1.8e-21 75.9 4.6 7.6e-10 38.8 0.2 5.1 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 ORY16076.1 - 4.4e-17 62.2 2.3 3.4e-08 33.9 0.0 5.4 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY16076.1 - 5.4e-15 54.0 1.2 0.0014 18.9 0.0 6.7 7 0 0 7 7 7 4 Ankyrin repeat Ank PF00023.30 ORY16076.1 - 2.5e-13 49.8 0.6 2.9e-05 24.3 0.0 5.5 4 0 0 4 4 4 2 Ankyrin repeat NACHT PF05729.12 ORY16076.1 - 3.1e-08 33.7 0.0 6.3e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 NACHT domain NACHT_N PF17100.5 ORY16076.1 - 1.4e-06 28.3 0.1 2.6e-06 27.5 0.1 1.4 1 0 0 1 1 1 1 N-terminal domain of NWD NACHT-NTPase AAA_16 PF13191.6 ORY16076.1 - 7.5e-06 26.4 0.0 2.8e-05 24.6 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 ORY16076.1 - 0.026 14.8 0.0 0.55 10.5 0.0 3.0 3 1 0 3 3 3 0 AAA domain ATPase_2 PF01637.18 ORY16076.1 - 0.11 12.3 0.0 0.4 10.5 0.0 2.0 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea TRI12 PF06609.13 ORY16078.1 - 4.6e-24 84.8 15.4 6.2e-24 84.4 15.4 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 ORY16078.1 - 8.7e-24 84.1 37.9 8.7e-24 84.1 37.9 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily MarR_2 PF12802.7 ORY16078.1 - 0.15 11.9 0.1 0.63 10.0 0.0 2.0 2 0 0 2 2 2 0 MarR family TauD PF02668.16 ORY16079.1 - 1.8e-52 178.8 0.6 2.1e-52 178.6 0.6 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family PDZ_1 PF12812.7 ORY16079.1 - 0.068 13.2 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 PDZ-like domain WRC PF08879.10 ORY16080.1 - 0.11 12.2 1.7 0.17 11.6 0.1 2.1 2 0 0 2 2 2 0 WRC Beta-lactamase PF00144.24 ORY16081.1 - 7.6e-43 147.0 0.0 9e-43 146.8 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.20 ORY16081.1 - 0.13 11.7 0.0 0.27 10.6 0.0 1.4 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase Esterase_phd PF10503.9 ORY16082.1 - 2.6e-05 23.8 0.0 7.5e-05 22.3 0.0 1.7 2 0 0 2 2 2 1 Esterase PHB depolymerase Abhydrolase_2 PF02230.16 ORY16082.1 - 0.0033 17.3 0.0 0.0055 16.5 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 ORY16082.1 - 0.0066 15.9 0.0 0.04 13.4 0.0 2.1 1 1 1 2 2 2 1 Prolyl oligopeptidase family AXE1 PF05448.12 ORY16082.1 - 0.0097 14.6 0.0 1 8.0 0.0 2.6 3 0 0 3 3 3 2 Acetyl xylan esterase (AXE1) Abhydrolase_3 PF07859.13 ORY16082.1 - 0.098 12.5 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold SOR_SNZ PF01680.17 ORY16083.1 - 8.9e-112 371.9 4.4 1.5e-111 371.1 4.4 1.4 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.14 ORY16083.1 - 4.5e-10 39.3 4.9 1.9e-06 27.4 0.2 2.4 2 1 0 2 2 2 2 Thiazole biosynthesis protein ThiG Dus PF01207.17 ORY16083.1 - 0.0012 18.0 1.1 0.3 10.1 0.0 2.5 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 ORY16083.1 - 0.0033 16.9 0.3 0.063 12.7 0.0 2.5 2 1 1 3 3 3 1 Histidine biosynthesis protein IGPS PF00218.21 ORY16083.1 - 0.0038 16.4 0.0 0.51 9.5 0.0 2.5 2 0 0 2 2 2 2 Indole-3-glycerol phosphate synthase NanE PF04131.14 ORY16083.1 - 0.0071 15.6 0.7 0.14 11.3 0.0 2.4 2 1 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase TetR_C_27 PF17935.1 ORY16083.1 - 0.011 15.8 0.0 0.028 14.5 0.0 1.6 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain TMP-TENI PF02581.17 ORY16083.1 - 0.04 13.3 0.1 1.2 8.4 0.0 2.6 2 0 0 2 2 2 0 Thiamine monophosphate synthase NMO PF03060.15 ORY16083.1 - 0.068 12.6 5.7 0.19 11.1 0.3 2.2 2 0 0 2 2 2 0 Nitronate monooxygenase Creatinase_N_2 PF16189.5 ORY16084.1 - 1.4e-54 184.5 0.0 3.5e-53 180.0 0.0 2.7 3 0 0 3 3 3 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 ORY16084.1 - 3.3e-45 154.3 0.0 6.2e-45 153.5 0.0 1.5 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.18 ORY16084.1 - 9.1e-21 74.9 0.0 3.2e-16 60.2 0.0 2.5 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain Peptidase_M24_C PF16188.5 ORY16084.1 - 5.6e-20 71.2 0.2 1.7e-19 69.6 0.2 1.9 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 Importin_rep PF18773.1 ORY16085.1 - 2e-05 24.2 0.0 0.0002 21.0 0.0 2.2 2 0 0 2 2 2 1 Importin 13 repeat CRM1_C PF08767.11 ORY16085.1 - 0.0061 15.8 0.8 0.029 13.6 0.0 2.3 2 0 0 2 2 2 1 CRM1 C terminal UNC80 PF15778.5 ORY16085.1 - 0.028 14.0 0.1 0.74 9.4 0.0 2.5 2 0 0 2 2 2 0 Cation channel complex component UNC80 UME PF08064.13 ORY16085.1 - 0.041 13.8 0.5 1.2 9.1 0.1 3.4 3 0 0 3 3 3 0 UME (NUC010) domain YyzF PF14116.6 ORY16085.1 - 0.097 12.7 0.1 0.25 11.4 0.1 1.7 1 0 0 1 1 1 0 YyzF-like protein IBN_N PF03810.19 ORY16085.1 - 0.15 12.0 2.2 1.4 8.8 0.0 3.6 5 0 0 5 5 5 0 Importin-beta N-terminal domain Sec7_N PF12783.7 ORY16085.1 - 0.7 9.8 5.8 2.6 7.9 0.4 3.8 4 1 0 4 4 4 0 Guanine nucleotide exchange factor in Golgi transport N-terminal FUN14 PF04930.15 ORY16086.1 - 5.1e-08 33.2 0.2 8.2e-08 32.6 0.2 1.3 1 0 0 1 1 1 1 FUN14 family Phosphodiest PF01663.22 ORY16087.1 - 3.5e-15 56.4 0.7 8.6e-09 35.4 0.1 2.2 1 1 1 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 ORY16087.1 - 8.1e-06 25.4 0.0 2.7e-05 23.7 0.0 1.7 2 0 0 2 2 2 1 Sulfatase Metalloenzyme PF01676.18 ORY16087.1 - 0.0024 17.3 0.0 0.0046 16.4 0.0 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily DUF2244 PF10003.9 ORY16088.1 - 0.059 13.0 0.5 0.063 12.9 0.5 1.2 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) Skp1 PF01466.19 ORY16090.1 - 5.6e-28 96.8 0.3 1e-27 96.0 0.3 1.5 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 ORY16090.1 - 2.3e-19 69.3 0.1 6.5e-19 67.9 0.0 1.8 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain Glyco_transf_22 PF03901.17 ORY16092.1 - 1.4e-62 212.2 21.9 1.9e-62 211.9 21.9 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family PLDc_2 PF13091.6 ORY16093.1 - 8e-14 51.7 0.0 3.4e-06 27.0 0.0 2.2 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 ORY16093.1 - 8.8e-09 35.2 2.1 0.0075 16.4 0.7 3.3 2 1 0 2 2 2 2 Phospholipase D Active site motif NDUFA12 PF05071.16 ORY16094.1 - 6.2e-28 97.5 4.2 7.4e-28 97.2 4.2 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 ABC_membrane PF00664.23 ORY16095.1 - 3.6e-55 187.6 27.5 2.5e-36 125.7 6.1 3.6 3 1 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 ORY16095.1 - 3.6e-55 186.2 0.0 1.1e-30 106.9 0.0 3.1 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 ORY16095.1 - 2.7e-08 34.0 0.2 0.0028 17.5 0.0 3.8 4 0 0 4 4 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ORY16095.1 - 5e-07 29.4 6.1 0.032 13.7 0.0 4.4 4 1 0 5 5 4 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 ORY16095.1 - 5.2e-07 30.4 0.5 0.00021 21.8 0.1 2.6 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 ORY16095.1 - 3.9e-05 23.7 0.6 0.077 13.1 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ORY16095.1 - 4.6e-05 23.4 0.0 0.063 13.2 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 ORY16095.1 - 7e-05 23.3 0.0 0.5 10.7 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 ORY16095.1 - 0.00012 22.4 0.2 1.7 8.9 0.0 3.4 3 0 0 3 3 3 2 AAA domain DUF87 PF01935.17 ORY16095.1 - 0.00014 22.1 0.5 0.064 13.4 0.0 2.7 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_29 PF13555.6 ORY16095.1 - 0.00041 20.0 0.5 0.2 11.4 0.1 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain T2SSE PF00437.20 ORY16095.1 - 0.0012 18.0 0.0 0.062 12.4 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein IstB_IS21 PF01695.17 ORY16095.1 - 0.0027 17.4 0.0 4 7.1 0.0 2.9 3 0 0 3 3 2 2 IstB-like ATP binding protein AAA_25 PF13481.6 ORY16095.1 - 0.0041 16.7 0.8 0.74 9.4 0.1 2.6 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 ORY16095.1 - 0.0045 16.3 0.8 2.8 7.2 0.0 3.0 3 0 0 3 3 3 1 Zeta toxin AAA_5 PF07728.14 ORY16095.1 - 0.0068 16.4 1.2 7.5 6.6 0.0 3.4 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_15 PF13175.6 ORY16095.1 - 0.0094 15.7 0.1 0.07 12.8 0.0 2.4 3 0 0 3 3 2 1 AAA ATPase domain AAA PF00004.29 ORY16095.1 - 0.01 16.2 0.3 6.7 7.1 0.0 3.4 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 ORY16095.1 - 0.011 15.5 0.1 1.9 8.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 ORY16095.1 - 0.022 14.2 0.3 3.5 7.1 0.1 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region CbiA PF01656.23 ORY16095.1 - 0.023 14.7 1.4 0.095 12.8 0.0 2.6 3 0 0 3 3 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Dynamin_N PF00350.23 ORY16095.1 - 0.034 14.2 1.8 4 7.5 0.1 2.7 2 0 0 2 2 2 0 Dynamin family DEAD PF00270.29 ORY16095.1 - 0.043 13.6 0.1 28 4.4 0.0 3.3 3 0 0 3 3 3 0 DEAD/DEAH box helicase RNA_helicase PF00910.22 ORY16095.1 - 0.046 14.1 0.2 14 6.1 0.0 2.8 3 0 0 3 3 2 0 RNA helicase TrwB_AAD_bind PF10412.9 ORY16095.1 - 0.051 12.5 1.1 3.5 6.4 0.0 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain cobW PF02492.19 ORY16095.1 - 0.053 13.1 2.4 0.26 10.9 0.3 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 ORY16095.1 - 0.064 13.4 0.0 5.7 7.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 ORY16095.1 - 0.1 11.8 0.2 12 5.0 0.0 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_18 PF13238.6 ORY16095.1 - 0.11 13.1 0.1 30 5.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 ORY16095.1 - 0.15 11.8 0.3 7 6.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain ResIII PF04851.15 ORY16095.1 - 0.16 11.9 0.0 7.5 6.5 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit NACHT PF05729.12 ORY16095.1 - 0.2 11.6 1.6 3.5 7.5 0.2 2.4 2 0 0 2 2 2 0 NACHT domain Pox_A32 PF04665.12 ORY16095.1 - 0.23 10.9 0.6 2.3 7.6 0.1 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein Roc PF08477.13 ORY16095.1 - 0.45 10.8 5.3 11 6.3 0.2 3.5 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase Swi5 PF07061.11 ORY16096.1 - 9.6e-26 89.7 0.3 9.8e-26 89.7 0.3 1.0 1 0 0 1 1 1 1 Swi5 Ytp1 PF10355.9 ORY16098.1 - 1.2e-71 241.2 16.4 1.2e-71 241.2 16.4 2.2 2 1 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 ORY16098.1 - 2.6e-31 107.5 1.4 2.6e-31 107.5 1.4 3.2 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) ExoD PF06055.12 ORY16098.1 - 0.003 17.0 0.1 0.003 17.0 0.1 2.4 3 0 0 3 3 3 1 Exopolysaccharide synthesis, ExoD ACC_epsilon PF13822.6 ORY16098.1 - 0.16 12.6 0.5 0.48 11.1 0.5 1.7 1 0 0 1 1 1 0 Acyl-CoA carboxylase epsilon subunit SSB PF00436.25 ORY16099.1 - 7.9e-15 54.8 0.0 9.6e-15 54.5 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family WD40 PF00400.32 ORY16100.1 - 5.5e-16 58.7 19.8 0.00013 22.7 0.1 6.5 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY16100.1 - 2e-05 24.8 0.0 2.2 8.6 0.0 4.1 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 ORY16100.1 - 0.0062 15.3 0.6 1.1 7.9 0.1 2.3 2 1 1 3 3 3 2 Nup133 N terminal like nec1 PF10379.9 ORY16100.1 - 0.029 13.8 0.0 0.054 13.0 0.0 1.3 1 0 0 1 1 1 0 Virulence protein nec1 Ge1_WD40 PF16529.5 ORY16100.1 - 0.057 12.4 0.0 0.42 9.5 0.0 2.1 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 ORY16100.1 - 0.24 11.3 0.4 5 7.0 0.0 3.1 4 1 0 4 4 4 0 Eukaryotic translation initiation factor eIF2A TFB6 PF17110.5 ORY16100.1 - 0.42 10.3 2.5 1.1 9.0 2.5 1.6 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH adh_short PF00106.25 ORY16101.1 - 6.2e-16 58.4 0.0 7.6e-16 58.1 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY16101.1 - 1.8e-10 40.7 0.0 2.3e-10 40.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY16101.1 - 2.3e-07 30.9 0.0 3.1e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ORY16101.1 - 0.004 16.7 0.0 0.0048 16.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 ORY16101.1 - 0.042 13.0 0.0 0.054 12.6 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein TRM13 PF05206.14 ORY16101.1 - 0.12 11.9 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase TRM13 Cation_efflux PF01545.21 ORY16102.1 - 4.2e-23 82.1 15.6 5.4e-23 81.8 15.6 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 ORY16102.1 - 3.7e-07 30.2 0.0 6.9e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter Peptidase_S8 PF00082.22 ORY16106.1 - 1.8e-06 27.4 0.0 3.3e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Subtilase family Ribosomal_L39 PF00832.20 ORY16109.1 - 5.1e-21 74.0 11.4 5.8e-21 73.8 11.4 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein CN_hydrolase PF00795.22 ORY16110.1 - 4.8e-13 49.1 0.0 8.9e-13 48.2 0.0 1.5 2 0 0 2 2 2 1 Carbon-nitrogen hydrolase ABC1 PF03109.16 ORY16111.1 - 9.7e-32 109.6 0.0 2.1e-31 108.6 0.0 1.6 1 0 0 1 1 1 1 ABC1 family STE PF02200.16 ORY16112.1 - 3.1e-56 188.5 0.1 5e-56 187.8 0.1 1.3 1 0 0 1 1 1 1 STE like transcription factor zf-C2H2 PF00096.26 ORY16112.1 - 1.5e-11 44.1 10.0 1.7e-06 28.1 0.6 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY16112.1 - 2.7e-09 37.0 2.5 2.7e-09 37.0 2.5 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORY16112.1 - 8.3e-08 32.4 8.1 0.00074 20.1 0.3 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 ORY16112.1 - 7e-05 22.7 3.3 0.00031 20.7 0.1 2.4 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORY16112.1 - 0.00087 19.5 0.1 0.024 14.9 0.0 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 ORY16112.1 - 0.0077 16.5 2.8 0.014 15.7 2.8 1.4 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 ORY16112.1 - 0.035 14.5 0.9 0.17 12.3 0.2 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type FYDLN_acid PF09538.10 ORY16112.1 - 0.039 14.6 0.2 0.094 13.4 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Zn-C2H2_12 PF18112.1 ORY16112.1 - 3.3 8.3 7.0 2.4 8.7 0.0 3.3 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain zf-H2C2_5 PF13909.6 ORY16112.1 - 6.4 6.6 5.7 28 4.6 3.0 2.6 2 0 0 2 2 2 0 C2H2-type zinc-finger domain CDP-OH_P_transf PF01066.21 ORY16113.1 - 7.2e-15 55.5 0.4 7.2e-15 55.5 0.4 2.2 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase TnsD PF15978.5 ORY16113.1 - 0.17 10.8 0.4 0.25 10.3 0.4 1.1 1 0 0 1 1 1 0 Tn7-like transposition protein D GIDA PF01134.22 ORY16114.1 - 3.8e-153 510.2 0.0 4.7e-153 509.9 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 ORY16114.1 - 2e-66 224.2 0.0 3.3e-66 223.5 0.0 1.3 1 0 0 1 1 1 1 GidA associated domain Pyr_redox_2 PF07992.14 ORY16114.1 - 5.2e-07 29.2 0.6 1.3e-06 27.9 0.7 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 ORY16114.1 - 5.4e-07 29.3 1.6 9.6e-07 28.5 1.6 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 ORY16114.1 - 0.00023 20.4 2.6 0.00023 20.4 2.6 1.8 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.21 ORY16114.1 - 0.0027 17.0 0.1 0.0061 15.9 0.1 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 ORY16114.1 - 0.0052 15.5 0.8 0.064 12.0 0.5 2.2 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 ORY16114.1 - 0.015 15.8 0.4 0.042 14.4 0.4 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ORY16114.1 - 0.04 13.9 0.0 0.13 12.3 0.0 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding adh_short PF00106.25 ORY16115.1 - 1.4e-29 103.0 0.1 5.2e-27 94.6 0.0 2.6 1 1 2 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.6 ORY16115.1 - 2.7e-23 82.8 0.0 6.3e-23 81.6 0.1 1.5 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY16115.1 - 1.4e-06 28.3 0.0 2.1e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 ORY16115.1 - 0.005 16.2 0.0 0.0095 15.3 0.0 1.4 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) WD40 PF00400.32 ORY16116.1 - 3.2e-26 91.1 22.3 1.5e-07 32.0 1.2 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat WD40_like PF17005.5 ORY16116.1 - 1.4e-07 31.2 0.0 0.013 14.9 0.0 2.5 2 1 0 3 3 3 2 WD40-like domain ANAPC4_WD40 PF12894.7 ORY16116.1 - 3.1e-07 30.6 3.7 1.1 9.6 0.0 4.7 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ORY16116.1 - 4.4e-06 25.6 3.5 1.2 7.7 0.0 4.6 1 1 4 5 5 5 3 Nucleoporin Nup120/160 PQQ_2 PF13360.6 ORY16116.1 - 4.9e-05 23.0 9.4 5.6e-05 22.8 1.3 2.3 1 1 0 2 2 2 1 PQQ-like domain PQQ_3 PF13570.6 ORY16116.1 - 0.0011 19.4 7.4 3.2 8.4 0.1 5.5 5 1 1 6 6 6 1 PQQ-like domain DUF5046 PF16465.5 ORY16116.1 - 0.0022 17.5 0.1 0.14 11.6 0.0 2.8 1 1 2 3 3 3 1 Domain of unknown function (DUF5046) Nucleoporin_N PF08801.11 ORY16116.1 - 0.0052 15.6 1.2 0.37 9.5 0.0 3.6 1 1 2 3 3 3 1 Nup133 N terminal like RicinB_lectin_2 PF14200.6 ORY16116.1 - 0.44 11.3 3.3 1.1 10.0 0.9 2.7 2 1 1 3 3 3 0 Ricin-type beta-trefoil lectin domain-like Tyrosinase PF00264.20 ORY16117.1 - 6.7e-35 121.4 0.1 1.1e-34 120.7 0.1 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase FIN1 PF17300.2 ORY16118.1 - 0.015 14.8 0.4 0.015 14.8 0.4 2.3 3 0 0 3 3 3 0 Filaments in between nuclei protein-1 Helo_like_N PF17111.5 ORY16118.1 - 0.066 12.6 1.3 0.16 11.3 1.3 1.7 1 1 0 1 1 1 0 Fungal N-terminal domain of STAND proteins XPC-binding PF09280.11 ORY16118.1 - 0.26 11.1 1.5 3.9 7.3 0.4 2.8 1 1 1 2 2 2 0 XPC-binding domain Tup_N PF08581.10 ORY16120.1 - 0.067 13.5 0.2 0.1 12.9 0.2 1.2 1 0 0 1 1 1 0 Tup N-terminal BTB PF00651.31 ORY16121.1 - 8.2e-05 22.8 0.0 0.00022 21.4 0.0 1.7 2 0 0 2 2 2 1 BTB/POZ domain INTS2 PF14750.6 ORY16121.1 - 0.08 10.5 0.0 0.1 10.2 0.0 1.0 1 0 0 1 1 1 0 Integrator complex subunit 2 Pep3_Vps18 PF05131.14 ORY16122.1 - 6.9e-47 159.0 0.0 1.6e-46 157.8 0.0 1.7 1 0 0 1 1 1 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 ORY16122.1 - 1.2e-09 38.1 9.2 2.5e-08 33.9 0.3 3.0 3 1 0 3 3 3 2 Region in Clathrin and VPS Zn_ribbon_17 PF17120.5 ORY16122.1 - 0.0017 17.9 0.2 0.0039 16.8 0.2 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 ORY16122.1 - 0.0021 18.0 0.2 0.0047 16.8 0.2 1.6 1 0 0 1 1 1 1 zinc-RING finger domain RPN1_RPN2_N PF17781.1 ORY16122.1 - 0.0026 17.2 0.1 0.0053 16.2 0.1 1.5 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain Vps39_2 PF10367.9 ORY16122.1 - 0.0035 17.8 0.0 0.0084 16.6 0.0 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 zf-C3HC4_2 PF13923.6 ORY16122.1 - 0.0042 16.9 0.9 0.012 15.4 0.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORY16122.1 - 0.057 13.8 0.7 0.057 13.8 0.7 1.8 2 0 0 2 2 1 0 Ring finger domain zf-RING_UBOX PF13445.6 ORY16122.1 - 0.075 13.1 0.4 0.17 12.0 0.4 1.6 1 0 0 1 1 1 0 RING-type zinc-finger DUF2175 PF09943.9 ORY16122.1 - 0.12 12.7 8.4 0.18 12.1 0.0 3.3 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2175) zf-rbx1 PF12678.7 ORY16122.1 - 0.14 12.4 0.3 0.38 11.1 0.3 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain DUF1664 PF07889.12 ORY16122.1 - 0.16 12.0 2.3 0.42 10.6 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) zf-C3HC4 PF00097.25 ORY16122.1 - 0.21 11.5 0.3 0.54 10.2 0.3 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 ORY16122.1 - 0.22 11.3 8.3 0.03 14.0 4.0 1.8 2 0 0 2 2 2 0 RING-like zinc finger XhlA PF10779.9 ORY16122.1 - 0.22 11.7 2.2 2.2 8.5 1.1 2.4 2 0 0 2 2 2 0 Haemolysin XhlA zf-C3H2C3 PF17122.5 ORY16122.1 - 1 9.5 6.7 0.11 12.5 2.0 1.8 2 0 0 2 2 2 0 Zinc-finger Pex2_Pex12 PF04757.14 ORY16123.1 - 0.008 15.8 2.0 0.018 14.7 1.0 2.0 2 1 0 2 2 2 1 Pex2 / Pex12 amino terminal region Kelch_5 PF13854.6 ORY16124.1 - 2e-11 43.6 6.3 4.9e-09 36.0 0.1 4.2 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.6 ORY16124.1 - 1.2e-08 34.8 10.9 0.091 12.8 0.2 5.7 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_6 PF13964.6 ORY16124.1 - 7.7e-08 32.4 9.1 0.12 12.7 0.0 5.6 6 0 0 6 6 6 3 Kelch motif Kelch_2 PF07646.15 ORY16124.1 - 0.00059 19.7 5.4 0.75 9.9 0.0 5.2 6 0 0 6 6 6 1 Kelch motif Kelch_1 PF01344.25 ORY16124.1 - 0.0036 16.8 5.4 0.8 9.3 0.0 5.1 6 0 0 6 6 6 1 Kelch motif Rax2 PF12768.7 ORY16124.1 - 0.084 12.3 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Cortical protein marker for cell polarity MtmB PF05369.12 ORY16125.1 - 0.11 11.3 0.1 0.16 10.8 0.1 1.3 1 0 0 1 1 1 0 Monomethylamine methyltransferase MtmB HATPase_c PF02518.26 ORY16126.1 - 5.5e-24 84.8 0.1 1.4e-23 83.6 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 ORY16126.1 - 2.4e-20 72.7 0.0 6.3e-20 71.4 0.0 1.8 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 ORY16126.1 - 1.9e-11 43.8 0.0 4.5e-11 42.6 0.0 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Musclin PF11037.8 ORY16127.1 - 0.048 13.6 0.2 0.085 12.8 0.2 1.3 1 0 0 1 1 1 0 Insulin-resistance promoting peptide in skeletal muscle UPF0060 PF02694.15 ORY16127.1 - 0.1 12.8 2.6 0.19 12.0 0.1 2.2 2 0 0 2 2 2 0 Uncharacterised BCR, YnfA/UPF0060 family Sugar_tr PF00083.24 ORY16128.1 - 2.1e-26 92.8 22.4 3.1e-18 65.9 7.0 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 ORY16128.1 - 1.8e-22 79.8 36.8 1.1e-14 54.1 14.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_holin_2_4 PF16082.5 ORY16128.1 - 0.064 13.0 0.1 0.19 11.4 0.1 1.9 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like Peptidase_M24 PF00557.24 ORY16129.1 - 9e-48 162.7 0.0 1.4e-47 162.1 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.18 ORY16129.1 - 0.00016 22.4 0.0 0.00027 21.6 0.0 1.4 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain DAO PF01266.24 ORY16130.1 - 9.2e-33 114.3 0.8 1.3e-32 113.8 0.8 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 ORY16130.1 - 5.1e-05 22.6 0.1 5.1e-05 22.6 0.1 2.1 3 0 0 3 3 3 1 Thi4 family NAD_binding_8 PF13450.6 ORY16130.1 - 0.00024 21.2 0.2 0.0015 18.7 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 ORY16130.1 - 0.0014 17.8 0.0 0.0014 17.8 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 ORY16130.1 - 0.0048 16.2 0.1 0.0048 16.2 0.1 2.7 3 1 1 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase DUF1188 PF06690.11 ORY16130.1 - 0.24 10.9 0.2 18 4.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1188) Pro_CA PF00484.19 ORY16132.1 - 5.2e-24 85.3 0.0 1e-23 84.4 0.1 1.5 2 0 0 2 2 2 1 Carbonic anhydrase Aminotran_4 PF01063.19 ORY16133.1 - 1.2e-40 139.8 0.0 1.5e-40 139.5 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV RTA1 PF04479.13 ORY16134.1 - 6.2e-63 212.1 13.3 8.2e-63 211.7 13.3 1.1 1 0 0 1 1 1 1 RTA1 like protein DUF89 PF01937.19 ORY16135.1 - 2.8e-131 437.7 0.0 3.3e-131 437.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 Amdase PF17645.1 ORY16139.1 - 6.2e-16 58.7 0.1 7.4e-16 58.4 0.1 1.1 1 0 0 1 1 1 1 Arylmalonate decarboxylase Asp_Glu_race PF01177.22 ORY16139.1 - 1.2e-09 38.3 0.0 1.4e-09 38.1 0.0 1.1 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase HTH_Tnp_Mu_1 PF02316.16 ORY16140.1 - 0.075 13.2 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 Mu DNA-binding domain Tenui_N PF05733.11 ORY16140.1 - 0.17 11.3 0.3 0.29 10.6 0.3 1.3 1 0 0 1 1 1 0 Tenuivirus/Phlebovirus nucleocapsid protein TPP_enzyme_N PF02776.18 ORY16141.1 - 1.2e-23 83.6 0.2 1.8e-22 79.8 0.2 2.1 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 ORY16141.1 - 9.3e-10 38.5 0.0 4.3e-09 36.3 0.0 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 ORY16141.1 - 0.013 15.3 0.0 0.029 14.1 0.0 1.7 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain ketoacyl-synt PF00109.26 ORY16143.1 - 7.3e-66 222.3 0.0 1.6e-65 221.2 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 ORY16143.1 - 4.8e-47 161.0 0.0 9.6e-47 160.0 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain SAT PF16073.5 ORY16143.1 - 3.2e-40 138.4 9.2 1.4e-39 136.2 0.2 3.8 3 1 0 3 3 3 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Ketoacyl-synt_C PF02801.22 ORY16143.1 - 7.2e-34 116.3 0.4 1.9e-33 115.0 0.4 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.20 ORY16143.1 - 3.6e-24 86.2 0.0 1.4e-23 84.2 0.0 2.1 2 0 0 2 2 2 1 Thioesterase domain PP-binding PF00550.25 ORY16143.1 - 1.3e-20 73.5 0.5 1.7e-11 44.3 0.1 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site PS-DH PF14765.6 ORY16143.1 - 8.9e-15 54.7 0.0 1.8e-14 53.7 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 ORY16143.1 - 6.1e-06 26.7 0.1 4.7e-05 23.8 0.0 2.4 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 ORY16143.1 - 0.076 12.4 0.3 0.18 11.1 0.3 1.6 1 0 0 1 1 1 0 Thiolase, N-terminal domain SnoaL_4 PF13577.6 ORY16144.1 - 6.9e-08 32.7 0.0 9.8e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain Methyltransf_15 PF09445.10 ORY16144.1 - 0.081 12.5 0.0 0.19 11.3 0.0 1.5 1 1 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Amidohydro_2 PF04909.14 ORY16145.1 - 1.9e-45 155.9 0.2 2.4e-45 155.6 0.2 1.1 1 0 0 1 1 1 1 Amidohydrolase Tyrosinase PF00264.20 ORY16146.1 - 2.1e-44 152.5 1.2 3e-44 151.9 1.2 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase DUF4010 PF13194.6 ORY16147.1 - 0.098 12.3 0.4 0.14 11.8 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4010) Sad1_UNC PF07738.13 ORY16148.1 - 2.1e-31 108.7 0.0 3.9e-31 107.8 0.0 1.5 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal CEP76-C2 PF15627.6 ORY16148.1 - 0.057 13.0 0.7 0.11 12.1 0.7 1.4 1 0 0 1 1 1 0 CEP76 C2 domain Pkinase PF00069.25 ORY16149.1 - 4.6e-50 170.4 0.0 7.1e-50 169.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY16149.1 - 8.6e-29 100.6 0.2 1.7e-28 99.7 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY16149.1 - 0.0017 17.7 0.1 0.0084 15.5 0.0 1.9 1 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 ORY16149.1 - 0.0038 16.6 0.0 0.0064 15.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family GET2 PF08690.10 ORY16149.1 - 0.028 14.1 4.1 0.043 13.5 4.1 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 APH PF01636.23 ORY16149.1 - 0.075 13.0 0.4 1.5 8.7 0.0 2.6 2 1 1 3 3 3 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 ORY16149.1 - 0.13 11.9 0.7 0.9 9.1 0.0 2.1 2 0 0 2 2 2 0 Choline/ethanolamine kinase Pkinase PF00069.25 ORY16150.1 - 1.6e-59 201.5 0.1 4e-53 180.5 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORY16150.1 - 2.6e-37 128.5 0.1 1.8e-35 122.5 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 ORY16150.1 - 4.6e-08 32.7 0.0 1e-06 28.3 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 ORY16150.1 - 0.00082 18.2 0.1 0.00082 18.2 0.1 2.4 2 1 0 2 2 2 1 Fungal protein kinase APH PF01636.23 ORY16150.1 - 0.0024 17.9 0.0 0.0042 17.0 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Sybindin PF04099.12 ORY16151.1 - 3.3e-25 88.7 0.0 4.4e-25 88.3 0.0 1.2 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 ORY16151.1 - 0.0071 16.5 0.0 0.0092 16.1 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Castor1_N PF18700.1 ORY16151.1 - 0.16 11.8 0.1 0.28 11.0 0.1 1.4 1 0 0 1 1 1 0 Cytosolic arginine sensor for mTORC1 subunit 1 N-terminal domain LTV PF04180.14 ORY16152.1 - 1.1e-122 410.6 17.2 1.2e-122 410.4 17.2 1.0 1 0 0 1 1 1 1 Low temperature viability protein MMR_HSR1 PF01926.23 ORY16153.1 - 2.5e-17 63.0 0.2 3.4e-15 56.1 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 ORY16153.1 - 2e-07 30.6 0.2 5.9e-06 25.9 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 ORY16153.1 - 9.1e-06 25.7 0.2 0.0027 17.6 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 ORY16153.1 - 0.0005 20.2 0.2 0.14 12.2 0.0 2.7 2 0 0 2 2 2 2 Dynamin family AIG1 PF04548.16 ORY16153.1 - 0.012 14.9 0.1 0.025 13.9 0.1 1.5 1 0 0 1 1 1 0 AIG1 family Acyl-CoA_dh_1 PF00441.24 ORY16154.1 - 1.1e-26 93.9 0.6 2e-26 93.0 0.6 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 ORY16154.1 - 2e-21 76.0 0.0 4e-21 75.0 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 ORY16154.1 - 1.8e-15 57.6 0.0 4.8e-15 56.2 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 ORY16154.1 - 8.2e-09 35.8 0.4 1.4e-08 35.1 0.4 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Harakiri PF15196.6 ORY16154.1 - 0.12 12.9 0.1 0.25 11.8 0.1 1.5 1 0 0 1 1 1 0 Activator of apoptosis harakiri APO_RNA-bind PF05634.11 ORY16155.1 - 0.094 12.1 0.2 0.11 11.8 0.2 1.2 1 0 0 1 1 1 0 APO RNA-binding DUF3920 PF13058.6 ORY16155.1 - 0.11 12.7 0.2 0.16 12.2 0.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3920) PP1_bind PF15276.6 ORY16157.1 - 0.13 12.6 0.1 0.29 11.5 0.1 1.5 1 0 0 1 1 1 0 Protein phosphatase 1 binding NACHT PF05729.12 ORY16158.1 - 1.9e-09 37.7 0.0 4.3e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 NACHT domain zf-C2H2 PF00096.26 ORY16158.1 - 6.9e-07 29.4 32.9 5.8e-05 23.3 2.9 5.2 5 0 0 5 5 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY16158.1 - 8.7e-07 29.1 1.9 8.7e-07 29.1 1.9 5.3 5 1 0 5 5 5 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORY16158.1 - 9.7e-06 26.0 26.5 0.0043 17.8 2.8 5.4 4 0 0 4 4 4 2 C2H2-type zinc finger zf-met PF12874.7 ORY16158.1 - 0.0012 19.2 1.0 0.0012 19.2 1.0 2.8 3 0 0 3 3 3 1 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.10 ORY16158.1 - 0.0042 17.2 1.6 0.014 15.5 1.6 2.0 1 0 0 1 1 1 1 Zinc ribbon domain AAA_22 PF13401.6 ORY16158.1 - 0.016 15.5 0.1 0.17 12.2 0.0 2.7 3 0 0 3 3 3 0 AAA domain KAP_NTPase PF07693.14 ORY16158.1 - 0.017 14.3 0.0 0.039 13.2 0.0 1.6 1 0 0 1 1 1 0 KAP family P-loop domain AAA_13 PF13166.6 ORY16158.1 - 0.019 13.6 0.0 0.1 11.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain zf-C2H2_jaz PF12171.8 ORY16158.1 - 0.027 14.8 7.8 0.74 10.2 0.6 4.2 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding AAA PF00004.29 ORY16158.1 - 0.028 14.8 0.0 0.11 12.9 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) zf-C2H2_6 PF13912.6 ORY16158.1 - 0.029 14.4 5.7 0.6 10.2 2.3 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger SNF2_N PF00176.23 ORY16159.1 - 5.2e-65 219.5 0.0 7.3e-65 219.0 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ORY16159.1 - 4.3e-15 56.0 0.0 1.6e-14 54.1 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 ORY16159.1 - 1.1e-08 35.1 0.0 2.8e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 ORY16159.1 - 6e-07 29.6 0.0 2e-06 27.9 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 ORY16159.1 - 0.0027 17.0 0.0 0.0054 16.0 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase zf-RING_5 PF14634.6 ORY16159.1 - 0.012 15.6 5.0 0.023 14.6 5.0 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.6 ORY16159.1 - 0.05 13.5 6.1 0.061 13.2 2.6 2.8 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORY16159.1 - 0.056 13.8 6.1 0.16 12.3 6.1 1.9 1 0 0 1 1 1 0 Ring finger domain SWI2_SNF2 PF18766.1 ORY16159.1 - 0.088 12.5 0.0 0.38 10.4 0.0 2.0 2 0 0 2 2 2 0 SWI2/SNF2 ATPase zf-C3HC4 PF00097.25 ORY16159.1 - 0.1 12.5 6.2 0.23 11.4 6.2 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 ORY16159.1 - 0.11 12.6 2.9 0.37 11.0 2.9 1.9 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 ORY16159.1 - 0.23 11.5 4.7 0.6 10.2 4.7 1.8 1 0 0 1 1 1 0 RING-type zinc-finger Prok-RING_4 PF14447.6 ORY16159.1 - 0.34 10.8 4.8 0.77 9.7 4.8 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 F-box PF00646.33 ORY16163.1 - 0.0047 16.8 0.0 0.011 15.6 0.0 1.7 1 0 0 1 1 1 1 F-box domain HATPase_c PF02518.26 ORY16164.1 - 1.6e-24 86.6 0.1 3.8e-24 85.4 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 ORY16164.1 - 4e-19 68.8 0.1 9.9e-19 67.6 0.1 1.8 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 ORY16164.1 - 1.8e-10 40.7 0.4 5e-10 39.3 0.4 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_4 PF08448.10 ORY16164.1 - 0.0011 19.2 0.1 0.0039 17.4 0.0 2.1 2 0 0 2 2 2 1 PAS fold PAS_3 PF08447.12 ORY16164.1 - 0.0042 17.3 0.3 0.026 14.8 0.0 2.5 3 0 0 3 3 3 1 PAS fold PAS_9 PF13426.7 ORY16164.1 - 0.028 14.7 0.0 0.076 13.3 0.0 1.8 1 0 0 1 1 1 0 PAS domain RecX PF02631.16 ORY16164.1 - 0.035 14.6 0.4 0.035 14.6 0.4 2.4 2 1 0 2 2 2 0 RecX family HATPase_c_3 PF13589.6 ORY16164.1 - 0.054 13.3 0.1 0.18 11.6 0.1 1.9 1 1 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase adh_short_C2 PF13561.6 ORY16165.1 - 2.8e-64 216.9 0.2 3.2e-64 216.7 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY16165.1 - 2.7e-51 173.8 0.2 3.5e-51 173.5 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORY16165.1 - 4.4e-16 59.3 1.2 1.3e-15 57.8 1.2 1.7 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 ORY16165.1 - 0.0013 18.0 0.1 0.0016 17.6 0.1 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 ORY16165.1 - 0.037 13.2 0.0 0.26 10.4 0.0 2.0 1 1 1 2 2 2 0 Male sterility protein 2-Hacid_dh_C PF02826.19 ORY16165.1 - 0.16 11.3 0.0 0.78 9.1 0.0 1.9 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HATPase_c PF02518.26 ORY16166.1 - 1.1e-26 93.5 0.0 2.8e-26 92.2 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 ORY16166.1 - 3.8e-23 81.8 0.2 7.1e-23 80.9 0.2 1.5 1 0 0 1 1 1 1 Response regulator receiver domain PAS_9 PF13426.7 ORY16166.1 - 4.3e-16 59.1 0.0 8.7e-14 51.6 0.0 2.6 2 0 0 2 2 2 1 PAS domain HisKA PF00512.25 ORY16166.1 - 3.3e-15 55.9 0.5 1.9e-14 53.4 0.5 2.4 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_4 PF08448.10 ORY16166.1 - 2.2e-13 50.4 0.2 3.5e-09 36.9 0.1 2.6 2 0 0 2 2 2 2 PAS fold PAS PF00989.25 ORY16166.1 - 1.5e-10 41.0 0.0 4.4e-09 36.3 0.0 2.6 2 0 0 2 2 2 1 PAS fold PAS_3 PF08447.12 ORY16166.1 - 0.00014 22.1 0.5 0.00043 20.5 0.3 2.0 2 0 0 2 2 2 1 PAS fold PAS_11 PF14598.6 ORY16166.1 - 0.022 14.9 0.0 0.2 11.8 0.0 2.3 2 0 0 2 2 2 0 PAS domain PAS_8 PF13188.7 ORY16166.1 - 0.12 12.4 0.0 0.31 11.1 0.0 1.7 1 0 0 1 1 1 0 PAS domain AAA_6 PF12774.7 ORY16166.1 - 0.15 11.0 0.1 0.27 10.1 0.1 1.4 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region SURF2 PF05477.11 ORY16167.1 - 5.4 6.6 11.4 8.9 5.9 11.4 1.3 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) TPR_12 PF13424.6 ORY16169.1 - 2.4e-112 367.4 113.5 8.1e-17 61.3 8.6 7.5 2 1 8 10 10 10 9 Tetratricopeptide repeat TPR_10 PF13374.6 ORY16169.1 - 4.9e-96 312.4 63.2 1.3e-10 40.8 0.7 10.7 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_1 PF00515.28 ORY16169.1 - 3.9e-48 159.4 56.4 6.6e-05 22.6 0.8 10.9 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_8 PF13181.6 ORY16169.1 - 3.1e-38 126.8 33.8 0.0072 16.5 0.1 11.0 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_2 PF07719.17 ORY16169.1 - 1.9e-37 124.3 56.5 0.0021 18.1 2.1 11.4 11 0 0 11 11 10 9 Tetratricopeptide repeat TPR_4 PF07721.14 ORY16169.1 - 2.9e-34 114.1 36.0 0.0013 19.2 2.5 10.8 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_7 PF13176.6 ORY16169.1 - 1.3e-29 100.0 58.2 0.0032 17.4 1.5 10.8 11 0 0 11 11 10 9 Tetratricopeptide repeat TPR_MalT PF17874.1 ORY16169.1 - 2.5e-27 96.1 34.0 2.9e-10 40.0 4.0 4.8 1 1 4 5 5 5 5 MalT-like TPR region TPR_14 PF13428.6 ORY16169.1 - 4.9e-24 83.0 55.6 0.098 13.5 1.1 11.2 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_16 PF13432.6 ORY16169.1 - 6.8e-19 68.2 71.9 0.0082 16.8 10.6 11.3 11 1 0 11 11 10 8 Tetratricopeptide repeat TPR_17 PF13431.6 ORY16169.1 - 6.9e-12 44.9 40.3 1.3 9.6 0.3 10.5 9 0 0 9 9 9 3 Tetratricopeptide repeat HET PF06985.11 ORY16169.1 - 6.2e-11 42.9 9.9 3.7e-09 37.1 2.5 2.9 2 1 1 3 3 2 2 Heterokaryon incompatibility protein (HET) NB-ARC PF00931.22 ORY16169.1 - 1e-10 41.2 0.0 1.5e-09 37.4 0.0 2.1 1 1 0 1 1 1 1 NB-ARC domain TPR_19 PF14559.6 ORY16169.1 - 1.8e-07 31.6 57.1 0.041 14.4 5.7 7.6 2 2 7 9 9 9 8 Tetratricopeptide repeat AAA_16 PF13191.6 ORY16169.1 - 5.9e-07 30.0 0.0 2.2e-06 28.1 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain PPR PF01535.20 ORY16169.1 - 2.8e-06 27.2 5.0 1.5e+02 2.9 0.0 9.8 10 0 0 10 10 10 0 PPR repeat TPR_21 PF09976.9 ORY16169.1 - 9.2e-06 25.5 48.2 1.4 8.6 0.0 9.6 2 1 8 10 10 10 2 Tetratricopeptide repeat-like domain TPR_11 PF13414.6 ORY16169.1 - 0.00018 21.1 58.8 4.9 6.9 0.2 10.7 10 0 0 10 10 10 4 TPR repeat ATPase_2 PF01637.18 ORY16169.1 - 0.00022 21.2 0.0 0.00036 20.5 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea DUF2225 PF09986.9 ORY16169.1 - 0.0048 16.6 10.2 0.066 12.9 0.5 3.8 1 1 4 5 5 5 1 Uncharacterized protein conserved in bacteria (DUF2225) DUF4810 PF16068.5 ORY16169.1 - 0.009 16.5 21.4 24 5.5 0.1 9.2 10 0 0 10 10 9 0 Domain of unknown function (DUF4810) RPN6_N PF18055.1 ORY16169.1 - 0.084 13.2 11.6 27 5.2 0.1 5.8 1 1 4 7 7 7 0 26S proteasome regulatory subunit RPN6 N-terminal domain DegV PF02645.16 ORY16169.1 - 2.2 7.6 9.5 8.5 5.6 0.2 4.3 4 1 2 6 6 6 0 Uncharacterised protein, DegV family COG1307 SARAF PF06682.12 ORY16170.1 - 8.9e-102 341.1 6.2 1e-101 340.9 6.2 1.0 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis PIG-X PF08320.12 ORY16171.1 - 2.4e-66 223.7 0.0 3.7e-66 223.0 0.0 1.3 1 0 0 1 1 1 1 PIG-X / PBN1 DUF4072 PF13284.6 ORY16171.1 - 0.03 14.7 0.3 0.072 13.5 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4072) ThiF PF00899.21 ORY16172.1 - 1.7e-31 109.5 0.0 2.1e-31 109.2 0.0 1.1 1 0 0 1 1 1 1 ThiF family Med7 PF05983.11 ORY16173.1 - 9.3 6.3 6.9 1.1 9.3 1.7 2.0 2 0 0 2 2 2 0 MED7 protein Kelch_5 PF13854.6 ORY16174.1 - 1.4e-05 24.9 0.1 1.4e-05 24.9 0.1 3.4 4 0 0 4 4 4 1 Kelch motif Kelch_4 PF13418.6 ORY16174.1 - 4.9e-05 23.3 0.3 0.94 9.5 0.0 3.4 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_6 PF13964.6 ORY16174.1 - 0.00013 22.1 4.2 0.64 10.4 0.0 4.4 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.25 ORY16174.1 - 0.0016 18.0 3.6 4.1 7.1 0.0 4.0 4 0 0 4 4 4 3 Kelch motif OCRE PF17780.1 ORY16174.1 - 0.025 14.6 0.5 0.12 12.5 0.3 2.3 2 0 0 2 2 2 0 OCRE domain Kelch_3 PF13415.6 ORY16174.1 - 0.31 11.4 3.5 21 5.5 0.0 3.8 4 0 0 4 4 4 0 Galactose oxidase, central domain SAC3_GANP PF03399.16 ORY16175.1 - 1.2e-77 261.3 0.3 1.2e-77 261.3 0.3 1.9 2 1 0 2 2 2 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 ORY16175.1 - 1.8e-05 24.7 0.0 0.00014 21.9 0.0 2.2 1 1 0 1 1 1 1 CSN8/PSMD8/EIF3K family MHC_II_alpha PF00993.20 ORY16175.1 - 0.017 14.8 0.1 0.13 12.0 0.1 2.4 1 1 1 2 2 2 0 Class II histocompatibility antigen, alpha domain DUF2841 PF11001.8 ORY16176.1 - 1e-08 35.3 0.0 1.9e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) DUF3929 PF13066.6 ORY16176.1 - 0.2 11.7 0.0 0.97 9.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3929) ABC_membrane PF00664.23 ORY16179.1 - 5e-84 282.2 25.2 6.4e-45 153.9 8.3 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 ORY16179.1 - 9.4e-51 171.9 0.0 8.6e-29 100.8 0.0 3.0 3 0 0 3 3 3 2 ABC transporter SMC_N PF02463.19 ORY16179.1 - 1.4e-08 34.5 3.4 0.0054 16.2 0.0 4.2 2 2 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 ORY16179.1 - 1.3e-06 28.9 2.0 0.0025 18.2 0.3 2.7 2 1 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 ORY16179.1 - 3.7e-06 27.0 1.3 0.12 12.5 0.1 3.1 3 0 0 3 3 3 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ORY16179.1 - 3.8e-05 23.6 0.0 0.018 15.0 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 ORY16179.1 - 0.00015 21.5 0.0 0.27 11.0 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 ORY16179.1 - 0.00035 20.5 0.5 0.55 10.0 0.0 3.2 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 ORY16179.1 - 0.00049 20.7 0.1 0.15 12.5 0.0 2.8 3 0 0 3 3 3 1 AAA domain T2SSE PF00437.20 ORY16179.1 - 0.01 14.9 0.0 0.08 12.0 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein Dynamin_N PF00350.23 ORY16179.1 - 0.011 15.8 1.1 1.2 9.1 0.1 2.5 2 0 0 2 2 2 0 Dynamin family AAA_30 PF13604.6 ORY16179.1 - 0.019 14.7 1.3 0.72 9.5 0.0 3.1 2 1 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 ORY16179.1 - 0.036 13.8 0.4 3.3 7.4 0.0 2.9 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_27 PF13514.6 ORY16179.1 - 0.04 13.5 0.0 0.24 11.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 ORY16179.1 - 0.062 12.6 0.0 9.9 5.4 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin CDC45 PF02724.14 ORY16179.1 - 0.067 11.5 0.0 0.17 10.1 0.0 1.6 2 0 0 2 2 2 0 CDC45-like protein AAA_22 PF13401.6 ORY16179.1 - 0.083 13.2 1.7 5.6 7.2 0.1 3.0 2 1 0 2 2 2 0 AAA domain Roc PF08477.13 ORY16179.1 - 0.14 12.4 0.4 38 4.5 0.0 3.2 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase AAA_15 PF13175.6 ORY16179.1 - 0.15 11.8 0.0 7.2 6.2 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain DUF87 PF01935.17 ORY16179.1 - 0.17 12.0 0.5 1.4 9.0 0.0 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain CCB1 PF12046.8 ORY16179.1 - 0.21 10.9 0.0 0.21 10.9 0.0 3.4 4 0 0 4 4 4 0 Cofactor assembly of complex C subunit B 60KD_IMP PF02096.20 ORY16179.1 - 0.25 11.2 5.0 0.83 9.5 5.0 1.8 1 0 0 1 1 1 0 60Kd inner membrane protein NACHT PF05729.12 ORY16179.1 - 0.72 9.8 3.0 4.4 7.2 0.1 3.0 3 0 0 3 3 3 0 NACHT domain UBA_4 PF14555.6 ORY16180.1 - 3.2e-07 30.1 0.0 8.5e-07 28.7 0.0 1.7 1 0 0 1 1 1 1 UBA-like domain HOOK PF05622.12 ORY16180.1 - 0.058 11.6 1.8 0.084 11.0 1.8 1.1 1 0 0 1 1 1 0 HOOK protein ING PF12998.7 ORY16180.1 - 0.11 13.1 2.2 0.35 11.5 2.2 1.9 1 1 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding THOC7 PF05615.13 ORY16180.1 - 0.39 11.0 4.1 2 8.7 0.3 2.4 2 0 0 2 2 2 0 Tho complex subunit 7 Pet127 PF08634.10 ORY16181.1 - 2.5e-112 374.8 0.0 3.6e-112 374.3 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial protein Pet127 RepB PF07506.11 ORY16181.1 - 0.069 13.2 0.1 13 5.8 0.1 2.5 3 0 0 3 3 3 0 RepB plasmid partitioning protein PH PF00169.29 ORY16182.1 - 0.078 13.5 0.0 0.45 11.0 0.0 2.3 1 1 0 1 1 1 0 PH domain LRR_1 PF00560.33 ORY16182.1 - 0.99 10.2 11.4 71 4.6 0.0 7.1 9 0 0 9 9 9 0 Leucine Rich Repeat LRR_6 PF13516.6 ORY16182.1 - 1.4 9.2 21.4 0.27 11.4 0.1 8.1 10 0 0 10 10 10 0 Leucine Rich repeat Bacteriocin_IIc PF10439.9 ORY16183.1 - 0.024 14.7 2.3 0.044 13.9 1.3 1.8 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide DER1 PF04511.15 ORY16184.1 - 2.3e-28 99.4 8.0 2.7e-28 99.2 8.0 1.0 1 0 0 1 1 1 1 Der1-like family RNA_pol_I_A49 PF06870.12 ORY16185.1 - 2.6e-90 303.1 0.7 3.1e-90 302.8 0.7 1.0 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor ADP_PFK_GK PF04587.15 ORY16185.1 - 0.046 12.3 0.1 0.075 11.6 0.1 1.3 1 0 0 1 1 1 0 ADP-specific Phosphofructokinase/Glucokinase conserved region Promethin PF16015.5 ORY16186.1 - 3.5e-30 104.1 18.4 4.7e-30 103.6 18.4 1.2 1 0 0 1 1 1 1 Promethin Syndecan PF01034.20 ORY16186.1 - 3.3 7.7 6.5 8.9 6.3 6.5 1.8 1 0 0 1 1 1 0 Syndecan domain DUF2070 PF09843.9 ORY16186.1 - 3.4 5.8 11.9 4.3 5.5 11.9 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) TssN PF17555.2 ORY16186.1 - 4.8 6.5 9.8 6.6 6.0 9.8 1.2 1 0 0 1 1 1 0 Type VI secretion system, TssN RTA1 PF04479.13 ORY16187.1 - 6e-75 251.4 10.8 8e-75 251.0 10.8 1.2 1 0 0 1 1 1 1 RTA1 like protein Poxvirus_B22R_C PF13168.6 ORY16187.1 - 0.15 11.5 0.8 0.27 10.7 0.8 1.3 1 0 0 1 1 1 0 Poxvirus B22R protein C-terminal adh_short PF00106.25 ORY16188.1 - 4.4e-31 107.9 0.0 5.3e-31 107.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY16188.1 - 1.2e-27 96.9 0.0 1.9e-27 96.3 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY16188.1 - 3.8e-09 36.7 0.1 5.4e-09 36.2 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ORY16188.1 - 0.16 11.4 0.1 2.5 7.5 0.1 2.2 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Pyr_redox_2 PF07992.14 ORY16189.1 - 4e-54 183.8 1.4 5e-54 183.5 1.4 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 ORY16189.1 - 8.9e-24 83.9 0.0 3.5e-23 81.9 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 ORY16189.1 - 6.4e-20 71.5 0.8 1.4e-19 70.4 0.8 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ORY16189.1 - 2.7e-09 36.7 0.0 4e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORY16189.1 - 6.1e-05 23.2 0.3 0.0067 16.6 0.1 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 ORY16189.1 - 0.0001 21.1 1.0 0.097 11.4 0.1 3.1 2 1 1 3 3 3 2 HI0933-like protein AlaDh_PNT_C PF01262.21 ORY16189.1 - 0.00015 21.1 0.2 0.00033 20.0 0.2 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 ORY16189.1 - 0.0013 17.9 1.5 0.39 9.7 0.1 2.6 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_2 PF00890.24 ORY16189.1 - 0.0021 17.2 2.5 2.3 7.2 0.0 3.6 2 1 2 4 4 4 2 FAD binding domain K_oxygenase PF13434.6 ORY16189.1 - 0.0033 16.6 0.0 0.0095 15.1 0.0 1.6 1 1 1 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) 3HCDH_N PF02737.18 ORY16189.1 - 0.054 13.4 0.2 0.088 12.7 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DAO PF01266.24 ORY16189.1 - 0.055 13.1 1.5 0.43 10.1 0.2 2.6 2 1 1 3 3 3 0 FAD dependent oxidoreductase TrkA_N PF02254.18 ORY16189.1 - 0.1 12.8 0.1 0.26 11.6 0.1 1.7 1 0 0 1 1 1 0 TrkA-N domain FAD_binding_3 PF01494.19 ORY16189.1 - 0.11 11.7 0.2 0.34 10.1 0.1 1.9 1 1 1 2 2 2 0 FAD binding domain MARVEL PF01284.23 ORY16190.1 - 2.5e-05 24.3 12.0 3.9e-05 23.7 12.0 1.2 1 0 0 1 1 1 1 Membrane-associating domain DUF4231 PF14015.6 ORY16190.1 - 0.22 12.0 1.6 0.35 11.4 0.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF4231) SecG PF03840.14 ORY16190.1 - 0.86 9.7 6.1 1.7 8.8 0.3 2.7 2 0 0 2 2 2 0 Preprotein translocase SecG subunit DUF1673 PF07895.11 ORY16190.1 - 1.8 8.2 4.3 0.51 10.0 1.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1673) eIF3_subunit PF08597.10 ORY16206.1 - 6.1e-71 239.2 29.5 7.3e-71 238.9 29.5 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit Rrn6 PF10214.9 ORY16206.1 - 4.1 5.8 14.4 7.2 5.0 14.4 1.3 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor CDC45 PF02724.14 ORY16206.1 - 9.4 4.4 17.2 15 3.7 17.2 1.3 1 0 0 1 1 1 0 CDC45-like protein Clathrin PF00637.20 ORY16207.1 - 1e-195 641.5 29.1 1.3e-32 112.6 1.2 7.8 8 0 0 8 8 8 7 Region in Clathrin and VPS Clathrin_H_link PF13838.6 ORY16207.1 - 1.2e-29 102.0 2.8 2.7e-29 100.9 0.6 2.9 2 0 0 2 2 2 1 Clathrin-H-link Clathrin_propel PF01394.20 ORY16207.1 - 3.9e-10 39.5 2.2 0.17 12.2 0.1 5.6 5 0 0 5 5 5 3 Clathrin propeller repeat Vps39_1 PF10366.9 ORY16207.1 - 1e-05 25.8 1.8 1.5 9.2 0.0 5.6 4 1 0 4 4 4 2 Vacuolar sorting protein 39 domain 1 TPR_14 PF13428.6 ORY16207.1 - 9.6e-05 22.9 10.0 1.3 10.0 0.1 8.0 9 0 0 9 9 7 1 Tetratricopeptide repeat Coatomer_WDAD PF04053.14 ORY16207.1 - 0.053 12.6 4.4 0.21 10.6 0.4 3.4 4 0 0 4 4 4 0 Coatomer WD associated region TPR_8 PF13181.6 ORY16207.1 - 0.098 12.9 6.1 0.53 10.6 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 ORY16207.1 - 0.26 11.4 9.0 35 4.8 0.1 6.8 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_1 PF00515.28 ORY16207.1 - 0.34 10.8 5.0 6.7 6.7 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 ORY16207.1 - 0.45 10.8 4.7 40 4.6 0.1 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 ORY16207.1 - 0.64 10.6 8.2 11 6.6 0.2 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 ORY16207.1 - 8.4 6.8 14.1 7.9 6.9 0.1 6.3 7 0 0 7 7 7 0 Tetratricopeptide repeat CPSase_L_D2 PF02786.17 ORY16208.1 - 1.9e-80 269.4 0.1 3.2e-80 268.6 0.1 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 ORY16208.1 - 2.9e-69 232.8 0.0 5.4e-69 231.9 0.0 1.5 1 0 0 1 1 1 1 Conserved carboxylase domain Biotin_carb_N PF00289.22 ORY16208.1 - 1.3e-39 135.1 0.0 2.5e-39 134.2 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 ORY16208.1 - 1e-30 106.0 0.0 2.3e-30 104.9 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.19 ORY16208.1 - 1.2e-29 103.7 0.0 2.5e-29 102.6 0.0 1.5 1 1 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.22 ORY16208.1 - 8.2e-18 64.0 1.6 1.9e-17 62.8 1.6 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 ORY16208.1 - 8.1e-09 35.3 0.0 1.6e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 ORY16208.1 - 7.6e-07 28.9 0.0 1.6e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 ORY16208.1 - 1.9e-06 27.6 0.2 0.00075 19.3 0.1 2.6 1 1 1 2 2 2 1 Biotin-lipoyl like ATP-grasp_3 PF02655.14 ORY16208.1 - 0.00015 21.9 0.0 0.00043 20.4 0.0 1.8 2 0 0 2 2 2 1 ATP-grasp domain RimK PF08443.11 ORY16208.1 - 0.0012 18.5 0.0 0.0033 17.1 0.0 1.7 1 1 0 1 1 1 1 RimK-like ATP-grasp domain HlyD_3 PF13437.6 ORY16208.1 - 0.004 17.8 0.1 4.3 8.1 0.0 2.7 2 0 0 2 2 2 2 HlyD family secretion protein HlyD_D23 PF16576.5 ORY16208.1 - 0.044 13.0 0.1 2.4 7.3 0.1 2.3 1 1 1 2 2 2 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion ATPgrasp_ST PF14397.6 ORY16208.1 - 0.11 11.7 0.0 0.28 10.4 0.0 1.6 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp RnfC_N PF13375.6 ORY16208.1 - 0.13 12.2 0.4 0.34 10.9 0.4 1.7 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain ATPgrasp_YheCD PF14398.6 ORY16208.1 - 0.16 11.2 0.0 10 5.3 0.0 2.2 2 0 0 2 2 2 0 YheC/D like ATP-grasp IGR PF09597.10 ORY16209.1 - 4.7e-25 87.4 0.0 8.2e-25 86.7 0.0 1.4 1 0 0 1 1 1 1 IGR protein motif Pkinase PF00069.25 ORY16210.1 - 3.1e-60 203.8 0.0 3.8e-60 203.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY16210.1 - 1.8e-32 112.6 0.0 2.5e-32 112.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY16210.1 - 0.0035 16.7 0.0 0.0059 16.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like DJ-1_PfpI PF01965.24 ORY16211.1 - 5.2e-15 55.6 0.0 1e-14 54.7 0.0 1.4 1 1 0 1 1 1 1 DJ-1/PfpI family AMP-binding PF00501.28 ORY16213.1 - 8.2e-28 97.1 0.0 1.3e-27 96.5 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 ORY16213.1 - 1.1e-07 32.1 0.0 2.3e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Transferase PF02458.15 ORY16213.1 - 3.8e-07 29.1 0.0 1.3e-05 24.0 0.0 2.7 2 1 0 2 2 2 1 Transferase family DIT1_PvcA PF05141.12 ORY16214.1 - 5.5e-92 308.1 0.0 7.6e-92 307.7 0.0 1.2 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein ABC2_membrane PF01061.24 ORY16214.1 - 1.4e-72 243.5 46.4 1.1e-37 129.5 16.3 3.1 2 1 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 ORY16214.1 - 3.4e-32 111.8 0.0 7.5e-15 55.6 0.0 2.8 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.12 ORY16214.1 - 1.1e-31 108.6 0.0 1.1e-31 108.6 0.0 3.5 4 0 0 4 4 3 1 CDR ABC transporter ABC_trans_N PF14510.6 ORY16214.1 - 1.5e-16 60.7 0.0 3.4e-16 59.6 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 ORY16214.1 - 1.1e-06 28.0 32.8 6.1e-06 25.6 7.6 2.9 2 1 1 3 3 3 2 ABC-2 family transporter protein AAA_16 PF13191.6 ORY16214.1 - 1.4e-06 28.8 0.3 0.011 16.1 0.1 2.9 3 0 0 3 3 3 2 AAA ATPase domain AAA_33 PF13671.6 ORY16214.1 - 5.1e-06 26.7 0.1 0.0015 18.7 0.1 2.5 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 ORY16214.1 - 5.3e-06 26.4 0.1 0.00013 21.9 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 ORY16214.1 - 0.00015 21.5 0.2 0.00093 18.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 ORY16214.1 - 0.00019 22.0 0.1 0.01 16.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 ORY16214.1 - 0.018 14.8 1.0 1.7 8.3 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 ORY16214.1 - 0.038 13.7 1.2 0.52 10.1 0.1 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain cobW PF02492.19 ORY16214.1 - 0.06 12.9 3.9 0.42 10.2 0.3 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 ORY16214.1 - 0.066 13.3 0.5 2.7 8.1 0.2 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_17 PF13207.6 ORY16214.1 - 0.1 13.0 1.5 0.9 10.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.6 ORY16214.1 - 0.11 12.2 0.1 18 5.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system NACHT PF05729.12 ORY16214.1 - 0.12 12.2 3.5 2.8 7.8 0.2 2.5 2 0 0 2 2 2 0 NACHT domain AAA_28 PF13521.6 ORY16214.1 - 0.17 12.2 0.8 1.3 9.2 0.1 2.3 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 ORY16214.1 - 0.18 11.2 0.0 2.4 7.5 0.0 2.5 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 ORY16214.1 - 0.23 11.7 5.2 1.8 8.8 0.2 2.9 2 0 0 2 2 2 0 AAA domain p450 PF00067.22 ORY16215.1 - 3.2e-53 181.1 0.0 4.1e-53 180.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 AIG2_2 PF13772.6 ORY16216.1 - 4e-05 23.9 0.0 0.00017 21.9 0.0 2.0 1 1 0 2 2 2 1 AIG2-like family HET PF06985.11 ORY16217.1 - 5.7e-20 72.2 0.0 8.9e-20 71.5 0.0 1.3 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) RabGAP-TBC PF00566.18 ORY16220.1 - 3.2e-20 72.7 0.0 5.4e-20 72.0 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SBE2 PF17076.5 ORY16220.1 - 1.2e-07 30.4 6.2 7.5e-07 27.8 0.9 2.1 2 0 0 2 2 2 2 SBE2, cell-wall formation NINJA_B PF16136.5 ORY16220.1 - 0.26 11.7 5.3 0.69 10.3 5.3 1.6 1 0 0 1 1 1 0 Putative nuclear localisation signal DUF4407 PF14362.6 ORY16220.1 - 2.9 7.2 4.4 5.5 6.3 4.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RhoGEF PF00621.20 ORY16222.1 - 3.2e-30 105.7 0.0 6.4e-30 104.7 0.0 1.5 1 0 0 1 1 1 1 RhoGEF domain BAR PF03114.18 ORY16222.1 - 0.006 16.3 1.3 0.0089 15.7 0.6 1.8 1 1 0 1 1 1 1 BAR domain Peptidase_U4 PF03419.13 ORY16224.1 - 0.64 9.2 4.5 0.99 8.6 4.5 1.2 1 0 0 1 1 1 0 Sporulation factor SpoIIGA Peptidase_M16_C PF05193.21 ORY16226.1 - 8.5e-25 87.8 0.0 1.8e-20 73.7 0.0 2.7 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 ORY16226.1 - 2e-05 24.6 0.0 0.00019 21.4 0.0 2.3 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) WD40 PF00400.32 ORY16227.1 - 4.9e-18 65.2 16.5 9.6e-07 29.4 0.1 6.7 7 0 0 7 7 7 4 WD domain, G-beta repeat NLE PF08154.12 ORY16227.1 - 1.6e-12 47.8 0.3 8.5e-12 45.4 0.1 2.2 2 0 0 2 2 2 1 NLE (NUC135) domain Nup160 PF11715.8 ORY16227.1 - 2.9e-06 26.2 0.0 0.00069 18.4 0.1 2.5 2 0 0 2 2 2 2 Nucleoporin Nup120/160 Trm112p PF03966.16 ORY16228.1 - 9.8e-11 42.1 0.3 2.6e-10 40.7 0.3 1.7 1 1 0 1 1 1 1 Trm112p-like protein Rad60-SLD PF11976.8 ORY16229.1 - 2.6e-17 62.4 0.0 9.3e-17 60.6 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 ORY16229.1 - 0.0051 16.5 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family LSM PF01423.22 ORY16230.1 - 9e-19 66.9 0.0 1.2e-18 66.6 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 ORY16230.1 - 0.0012 19.0 0.0 0.0021 18.2 0.0 1.5 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 ORY16230.1 - 0.059 13.5 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Scd6-like Sm domain MatB PF16449.5 ORY16233.1 - 0.061 13.1 0.0 0.091 12.5 0.0 1.2 1 0 0 1 1 1 0 Fimbrillin MatB TPR_19 PF14559.6 ORY16241.1 - 3e-09 37.3 0.0 0.002 18.6 0.0 4.1 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 ORY16241.1 - 1e-08 34.6 0.5 0.00012 21.9 0.1 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 ORY16241.1 - 6.8e-08 32.5 0.2 1.8e-07 31.2 0.2 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 ORY16241.1 - 2.8e-07 30.8 5.8 0.0011 19.7 0.1 5.7 3 1 2 6 6 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 ORY16241.1 - 2.2e-06 27.3 0.2 0.0046 16.6 0.0 4.7 4 1 1 5 5 5 2 TPR repeat TPR_17 PF13431.6 ORY16241.1 - 2.5e-05 24.3 0.5 0.0074 16.6 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 ORY16241.1 - 6.2e-05 22.6 0.1 0.025 14.4 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 ORY16241.1 - 0.0002 22.0 0.6 0.019 15.6 0.0 3.4 4 0 0 4 4 3 1 Tetratricopeptide repeat Wzy_C_2 PF11846.8 ORY16241.1 - 0.0021 18.0 0.0 0.12 12.3 0.0 2.3 2 0 0 2 2 2 1 Virulence factor membrane-bound polymerase, C-terminal TPR_7 PF13176.6 ORY16241.1 - 0.01 15.8 1.1 11 6.3 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 ORY16241.1 - 0.013 15.7 0.0 1.9 8.9 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 ORY16241.1 - 0.024 15.3 0.0 4.7 8.1 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat BTAD PF03704.17 ORY16241.1 - 0.049 14.1 0.3 0.27 11.7 0.2 2.1 1 1 0 2 2 2 0 Bacterial transcriptional activator domain TPR_20 PF14561.6 ORY16241.1 - 0.079 13.3 0.0 0.48 10.8 0.0 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 ORY16241.1 - 0.14 12.5 1.3 4.9 7.5 0.2 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat Adaptin_N PF01602.20 ORY16242.1 - 1.4e-78 264.8 0.0 3.7e-78 263.4 0.0 1.6 1 1 0 1 1 1 1 Adaptin N terminal region HEAT_EZ PF13513.6 ORY16242.1 - 0.00097 19.6 2.9 3.4 8.3 0.0 4.8 5 0 0 5 5 5 2 HEAT-like repeat Cnd1 PF12717.7 ORY16242.1 - 0.0062 16.6 0.0 0.19 11.8 0.0 2.5 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 ORY16242.1 - 0.028 14.8 1.0 0.64 10.4 0.0 3.5 3 0 0 3 3 3 0 HEAT repeats RAMP4 PF06624.12 ORY16243.1 - 6.8e-18 64.5 0.5 1.1e-17 63.8 0.1 1.5 2 0 0 2 2 2 1 Ribosome associated membrane protein RAMP4 ACT_7 PF13840.6 ORY16244.1 - 0.067 13.0 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 ACT domain Gemini_AL2 PF01440.16 ORY16244.1 - 0.23 11.9 0.9 0.32 11.4 0.9 1.2 1 0 0 1 1 1 0 Geminivirus AL2 protein Glyco_transf_20 PF00982.21 ORY16245.1 - 0.0002 20.2 0.0 0.00026 19.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 MATalpha_HMGbox PF04769.12 ORY16247.1 - 0.0098 15.2 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 HMG-box Integrin_alpha PF00357.20 ORY16248.1 - 0.1 12.7 0.7 0.21 11.7 0.7 1.6 1 0 0 1 1 1 0 Integrin alpha cytoplasmic region ADH_zinc_N PF00107.26 ORY16249.1 - 1.2e-09 38.3 0.2 2.1e-09 37.5 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ORY16249.1 - 4.8e-05 23.2 0.0 0.00014 21.8 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain DUF4604 PF15377.6 ORY16250.1 - 0.13 12.7 0.1 0.17 12.3 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) DUF3176 PF11374.8 ORY16251.1 - 2.5 8.4 6.3 0.62 10.3 1.9 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3176) Ank_2 PF12796.7 ORY16252.1 - 6.2e-20 71.6 0.0 2.3e-07 31.3 0.0 3.5 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ORY16252.1 - 1.7e-14 52.5 0.3 0.013 16.0 0.0 6.6 5 1 1 6 6 6 2 Ankyrin repeat Ank_4 PF13637.6 ORY16252.1 - 2.5e-14 53.5 0.1 0.045 14.4 0.0 4.9 4 1 0 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 ORY16252.1 - 3.6e-08 33.5 0.2 0.091 13.1 0.0 4.8 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 ORY16252.1 - 6.3e-07 29.6 0.2 0.068 13.6 0.1 4.8 4 0 0 4 4 4 1 Ankyrin repeat DUF3253 PF11625.8 ORY16252.1 - 0.085 13.1 0.1 0.22 11.8 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3253) SIS PF01380.22 ORY16254.1 - 2.6e-56 189.0 0.1 5.4e-31 107.1 0.0 2.4 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 ORY16254.1 - 9.9e-18 64.6 0.0 1.9e-17 63.7 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 ORY16254.1 - 1.6e-10 41.0 0.0 3.8e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 ORY16254.1 - 0.00056 18.9 0.0 0.00087 18.3 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.6 ORY16254.1 - 0.036 14.1 0.1 1.5 8.8 0.0 2.8 3 0 0 3 3 3 0 SIS domain DMRL_synthase PF00885.19 ORY16255.1 - 8.9e-54 181.1 0.0 1.1e-53 180.9 0.0 1.1 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase Aldo_ket_red PF00248.21 ORY16256.1 - 7.1e-55 186.3 0.0 8.9e-55 185.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family NAD_Gly3P_dh_N PF01210.23 ORY16258.1 - 3.1e-48 163.7 0.1 1.9e-47 161.1 0.0 2.0 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 ORY16258.1 - 4.5e-46 156.7 0.2 7.3e-46 156.0 0.2 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus DUF4687 PF15747.5 ORY16259.1 - 0.062 13.8 0.0 0.14 12.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4687) DUF1908 PF08926.11 ORY16259.1 - 0.68 9.0 4.3 1.2 8.2 4.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1908) MFS_1 PF07690.16 ORY16260.1 - 4.6e-38 131.1 49.5 4.6e-38 131.1 49.5 2.3 3 1 0 3 3 3 1 Major Facilitator Superfamily Oxidored_q2 PF00420.24 ORY16260.1 - 0.23 11.1 0.0 0.23 11.1 0.0 3.9 3 1 0 3 3 3 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L AAA PF00004.29 ORY16261.1 - 1.6e-29 103.0 0.0 2.5e-29 102.4 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 ORY16261.1 - 6.9e-07 29.6 0.2 5.8e-06 26.6 0.2 2.2 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.14 ORY16261.1 - 9.1e-07 29.1 0.0 1.9e-05 24.8 0.0 2.1 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 ORY16261.1 - 1.2e-06 28.7 0.1 2.6e-06 27.7 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ORY16261.1 - 2.5e-06 28.0 0.0 4.9e-06 27.0 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain Sigma54_activat PF00158.26 ORY16261.1 - 1.7e-05 24.6 0.0 3.1e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_18 PF13238.6 ORY16261.1 - 1.9e-05 25.2 0.0 2.8e-05 24.7 0.0 1.4 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 ORY16261.1 - 4.2e-05 23.5 0.1 0.00022 21.2 0.1 2.1 1 1 0 1 1 1 1 NACHT domain AAA_25 PF13481.6 ORY16261.1 - 5.8e-05 22.7 0.2 0.0092 15.6 0.1 2.2 1 1 1 2 2 2 1 AAA domain AAA_24 PF13479.6 ORY16261.1 - 8.5e-05 22.4 0.0 0.00017 21.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 ORY16261.1 - 0.00012 21.9 0.2 0.00026 20.8 0.2 1.7 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 ORY16261.1 - 0.00012 22.1 0.0 0.0002 21.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 ORY16261.1 - 0.00016 21.5 0.0 0.00025 20.9 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_5 PF07728.14 ORY16261.1 - 0.00019 21.4 0.6 0.0015 18.6 0.6 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 ORY16261.1 - 0.00019 21.8 0.1 0.0016 18.8 0.1 2.2 1 1 0 1 1 1 1 RNA helicase DnaB_C PF03796.15 ORY16261.1 - 0.00034 20.0 0.1 0.043 13.1 0.0 2.1 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 ORY16261.1 - 0.00034 20.4 0.2 0.0012 18.6 0.2 1.9 1 1 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 ORY16261.1 - 0.00059 19.3 0.0 0.00096 18.6 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_30 PF13604.6 ORY16261.1 - 0.00081 19.2 0.0 0.0013 18.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 ORY16261.1 - 0.00099 19.1 0.1 0.0027 17.7 0.0 1.6 1 1 0 1 1 1 1 Rad17 P-loop domain KTI12 PF08433.10 ORY16261.1 - 0.00099 18.6 0.1 0.0019 17.7 0.1 1.5 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_28 PF13521.6 ORY16261.1 - 0.0013 18.9 0.1 0.0049 17.1 0.0 1.9 2 1 1 3 3 2 1 AAA domain TsaE PF02367.17 ORY16261.1 - 0.0014 18.6 0.0 0.0023 17.9 0.0 1.3 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE T2SSE PF00437.20 ORY16261.1 - 0.0029 16.7 0.1 0.008 15.3 0.0 1.7 2 0 0 2 2 2 1 Type II/IV secretion system protein Cytidylate_kin PF02224.18 ORY16261.1 - 0.0033 17.2 0.1 0.0054 16.5 0.1 1.4 1 1 0 1 1 1 1 Cytidylate kinase TIP49 PF06068.13 ORY16261.1 - 0.0037 16.5 0.0 0.0058 15.9 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain dNK PF01712.19 ORY16261.1 - 0.0041 17.0 0.0 0.0077 16.1 0.0 1.5 1 0 0 1 1 1 1 Deoxynucleoside kinase Zeta_toxin PF06414.12 ORY16261.1 - 0.0076 15.6 0.0 0.015 14.6 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_23 PF13476.6 ORY16261.1 - 0.0084 16.6 0.1 0.023 15.2 0.0 1.6 1 1 1 2 2 2 1 AAA domain NTPase_1 PF03266.15 ORY16261.1 - 0.0086 16.0 0.1 0.032 14.1 0.0 1.9 2 0 0 2 2 2 1 NTPase AAA_17 PF13207.6 ORY16261.1 - 0.0093 16.4 0.0 0.023 15.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 ORY16261.1 - 0.011 16.2 0.0 0.02 15.4 0.0 1.4 1 1 0 1 1 1 0 ABC transporter DUF2075 PF09848.9 ORY16261.1 - 0.013 14.8 0.0 0.017 14.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 ORY16261.1 - 0.015 15.3 0.0 0.033 14.2 0.0 1.6 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit NB-ARC PF00931.22 ORY16261.1 - 0.016 14.4 0.0 0.024 13.8 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_11 PF13086.6 ORY16261.1 - 0.022 14.6 0.6 0.044 13.6 0.6 1.6 1 1 0 1 1 1 0 AAA domain ATPase PF06745.13 ORY16261.1 - 0.023 14.0 0.2 1.5 8.2 0.0 2.2 1 1 1 2 2 2 0 KaiC PhoH PF02562.16 ORY16261.1 - 0.027 13.9 0.0 0.056 12.9 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein CPT PF07931.12 ORY16261.1 - 0.028 14.3 0.0 0.061 13.2 0.0 1.6 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_29 PF13555.6 ORY16261.1 - 0.036 13.8 0.0 0.081 12.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_3 PF07726.11 ORY16261.1 - 0.044 13.6 0.0 0.095 12.6 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 ORY16261.1 - 0.046 13.6 0.0 0.17 11.8 0.0 1.8 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea SRPRB PF09439.10 ORY16261.1 - 0.049 13.0 0.1 0.096 12.1 0.0 1.5 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit cobW PF02492.19 ORY16261.1 - 0.053 13.1 0.2 0.16 11.5 0.0 1.8 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain APS_kinase PF01583.20 ORY16261.1 - 0.054 13.4 0.0 0.093 12.6 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase Hydin_ADK PF17213.3 ORY16261.1 - 0.061 13.6 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain AAA_19 PF13245.6 ORY16261.1 - 0.073 13.4 0.3 0.28 11.5 0.0 1.9 1 1 1 2 2 2 0 AAA domain SRP54 PF00448.22 ORY16261.1 - 0.076 12.6 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain PduV-EutP PF10662.9 ORY16261.1 - 0.088 12.6 0.0 0.3 10.8 0.0 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 ORY16261.1 - 0.091 12.3 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region SKI PF01202.22 ORY16261.1 - 0.092 12.9 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Shikimate kinase Cytidylate_kin2 PF13189.6 ORY16261.1 - 0.094 12.8 0.0 0.21 11.7 0.0 1.4 1 1 0 1 1 1 0 Cytidylate kinase-like family Ploopntkinase3 PF18751.1 ORY16261.1 - 0.18 11.7 0.0 0.42 10.5 0.0 1.7 2 0 0 2 2 1 0 P-loop Nucleotide Kinase3 RSN1_7TM PF02714.15 ORY16262.1 - 2.2e-70 237.1 15.1 2.2e-70 237.1 15.1 2.0 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 ORY16262.1 - 7.1e-38 130.6 0.0 1e-37 130.1 0.0 1.2 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 ORY16262.1 - 7.6e-35 120.0 0.8 7.6e-35 120.0 0.8 3.0 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport Anoctamin PF04547.12 ORY16262.1 - 0.0009 18.2 2.5 0.0011 18.0 0.6 2.0 2 0 0 2 2 2 1 Calcium-activated chloride channel RRM_1 PF00076.22 ORY16262.1 - 0.087 12.7 0.1 2.1 8.2 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) YMF19 PF02326.15 ORY16262.1 - 0.24 12.2 4.8 0.83 10.5 0.2 3.1 2 0 0 2 2 2 0 Plant ATP synthase F0 DUF4743 PF15916.5 ORY16262.1 - 0.26 11.2 1.4 1.2 9.1 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4743) Ost5 PF05251.12 ORY16262.1 - 4.3 7.7 11.1 26 5.2 0.0 4.6 4 0 0 4 4 4 0 Oligosaccharyltransferase subunit 5 F-box PF00646.33 ORY16263.1 - 7.2e-08 32.1 0.0 0.0076 16.1 0.1 3.3 2 0 0 2 2 2 2 F-box domain F-box-like PF12937.7 ORY16263.1 - 2.3e-07 30.6 0.1 0.0015 18.4 0.0 2.8 2 0 0 2 2 2 2 F-box-like tRNA-synt_1d PF00750.19 ORY16264.1 - 4.2e-63 213.4 0.1 5.7e-63 213.0 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 ORY16264.1 - 9e-16 58.1 0.1 2e-15 57.0 0.1 1.6 1 0 0 1 1 1 1 DALR anticodon binding domain Helo_like_N PF17111.5 ORY16265.1 - 1.7e-71 239.9 5.3 1.2e-70 237.2 0.6 2.1 2 0 0 2 2 2 2 Fungal N-terminal domain of STAND proteins SesA PF17107.5 ORY16265.1 - 0.0021 18.2 1.3 0.0068 16.6 0.1 2.4 3 0 0 3 3 3 1 N-terminal domain on NACHT_NTPase and P-loop NTPases HsbA PF12296.8 ORY16265.1 - 0.01 16.2 2.6 0.032 14.6 1.7 2.3 2 0 0 2 2 2 0 Hydrophobic surface binding protein A NPV_P10 PF05531.12 ORY16265.1 - 0.025 15.0 0.6 0.12 12.9 0.2 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF3829 PF12889.7 ORY16265.1 - 0.031 13.8 0.2 0.097 12.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3829) PRESAN PF09687.10 ORY16265.1 - 0.049 14.2 1.9 4.2 7.9 0.1 3.1 2 1 1 3 3 3 0 Plasmodium RESA N-terminal DUF2976 PF11190.8 ORY16265.1 - 0.12 12.1 0.1 1.1 9.1 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2976) Fez1 PF06818.15 ORY16265.1 - 0.54 10.7 3.7 6 7.3 3.7 2.2 1 1 0 1 1 1 0 Fez1 FliD_N PF02465.18 ORY16265.1 - 0.74 10.5 4.9 5.8 7.7 0.5 3.1 3 1 0 3 3 3 0 Flagellar hook-associated protein 2 N-terminus SlyX PF04102.12 ORY16265.1 - 0.97 10.1 3.3 3 8.5 0.3 3.1 3 0 0 3 3 3 0 SlyX SLATT_5 PF18160.1 ORY16265.1 - 1.3 8.3 4.3 0.43 9.9 0.2 2.1 3 0 0 3 3 3 0 SMODS and SLOG-associating 2TM effector domain family 5 Syntaxin-6_N PF09177.11 ORY16265.1 - 2 9.0 5.5 2.1 9.0 0.6 3.2 1 1 0 2 2 2 0 Syntaxin 6, N-terminal Cep57_CLD_2 PF14197.6 ORY16265.1 - 4 7.6 6.7 9 6.5 1.6 2.8 3 0 0 3 3 2 0 Centrosome localisation domain of PPC89 Asp_protease_2 PF13650.6 ORY16266.1 - 0.00015 22.4 0.0 0.013 16.1 0.0 2.3 2 0 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 ORY16266.1 - 0.00099 19.6 0.0 0.004 17.7 0.0 1.9 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Phage_Coat_B PF05356.11 ORY16267.1 - 7e-05 22.7 0.5 0.00013 21.8 0.5 1.5 1 0 0 1 1 1 1 Phage Coat protein B Podoplanin PF05808.11 ORY16267.1 - 0.0023 18.1 3.2 0.0033 17.5 3.2 1.2 1 0 0 1 1 1 1 Podoplanin Mucin PF01456.17 ORY16267.1 - 0.015 15.3 18.6 0.015 15.3 18.6 1.7 2 0 0 2 2 1 0 Mucin-like glycoprotein stn_TNFRSF12A PF12191.8 ORY16267.1 - 0.017 15.4 0.1 0.043 14.0 0.1 1.7 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain EphA2_TM PF14575.6 ORY16267.1 - 0.026 15.4 0.0 0.54 11.2 0.0 2.3 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain FeoB_associated PF12669.7 ORY16267.1 - 0.091 13.2 0.9 0.091 13.2 0.9 3.0 3 0 0 3 3 2 0 FeoB-associated Cys-rich membrane protein TMEM154 PF15102.6 ORY16267.1 - 0.14 12.1 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 TMEM154 protein family Vpu PF00558.19 ORY16267.1 - 0.16 11.8 0.1 0.33 10.8 0.1 1.4 1 0 0 1 1 1 0 Vpu protein DUF2561 PF10812.8 ORY16267.1 - 0.16 12.0 3.4 0.26 11.3 3.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) DUF2207 PF09972.9 ORY16267.1 - 0.24 10.1 0.7 0.33 9.6 0.0 1.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Alpha_GJ PF03229.13 ORY16267.1 - 0.8 10.3 12.9 1.5 9.4 12.9 1.4 1 0 0 1 1 1 0 Alphavirus glycoprotein J DUF4491 PF14898.6 ORY16267.1 - 0.96 9.9 2.7 2 8.9 2.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4491) Patched PF02460.18 ORY16267.1 - 6.7 4.6 5.0 9.2 4.2 5.0 1.1 1 0 0 1 1 1 0 Patched family HlyD_D4 PF16572.5 ORY16268.1 - 0.24 11.3 0.9 3.2 7.7 0.0 2.5 1 1 1 2 2 2 0 Long alpha hairpin domain of cation efflux system protein, CusB UPF0029 PF01205.19 ORY16269.1 - 1.8e-18 66.8 1.4 2.7e-18 66.2 0.0 1.9 3 0 0 3 3 3 1 Uncharacterized protein family UPF0029 Ribosomal_L34 PF00468.17 ORY16270.1 - 5.5e-16 58.3 9.2 7.5e-16 57.8 9.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L34 Peptidase_M48_N PF16491.5 ORY16272.1 - 5.9e-61 205.5 5.6 1.1e-60 204.7 5.6 1.4 1 0 0 1 1 1 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 ORY16272.1 - 2.2e-45 154.8 0.0 1e-44 152.7 0.0 1.9 2 0 0 2 2 2 1 Peptidase family M48 Peptidase_M56 PF05569.11 ORY16272.1 - 3.8e-06 26.3 1.0 5.1e-05 22.6 0.6 2.5 2 1 0 2 2 2 1 BlaR1 peptidase M56 DUF2268 PF10026.9 ORY16272.1 - 0.01 15.5 0.0 0.02 14.5 0.0 1.4 1 0 0 1 1 1 1 Predicted Zn-dependent protease (DUF2268) DUF4538 PF15061.6 ORY16272.1 - 0.12 12.1 0.8 0.35 10.6 0.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4538) Helo_like_N PF17111.5 ORY16273.1 - 0.00034 20.1 0.6 0.0007 19.0 0.6 1.5 1 1 0 1 1 1 1 Fungal N-terminal domain of STAND proteins HATPase_c_3 PF13589.6 ORY16274.1 - 0.017 15.0 0.0 0.039 13.8 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GHMP_kinases_N PF00288.26 ORY16276.1 - 2.8e-15 56.3 0.0 7.4e-15 54.9 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 ORY16276.1 - 3.6e-08 33.7 0.0 1e-07 32.2 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal Prok-RING_2 PF14445.6 ORY16277.1 - 0.01 15.9 0.2 0.018 15.2 0.2 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 2 Reticulon PF02453.17 ORY16277.1 - 0.03 14.3 0.1 0.033 14.2 0.1 1.2 1 0 0 1 1 1 0 Reticulon G-patch PF01585.23 ORY16278.1 - 4.6e-05 23.2 0.1 0.00029 20.7 0.1 2.4 1 1 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 ORY16278.1 - 0.68 10.1 0.0 0.68 10.1 0.0 3.4 4 0 0 4 4 4 0 G-patch domain LAP1C PF05609.12 ORY16278.1 - 1.6 7.7 28.8 2.5 7.1 28.8 1.3 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) rRNA_processing PF08524.11 ORY16279.1 - 0.013 15.5 0.4 0.013 15.5 0.4 2.1 2 0 0 2 2 2 0 rRNA processing CT_C_D PF02682.16 ORY16279.1 - 0.11 12.3 0.3 0.15 11.7 0.3 1.2 1 0 0 1 1 1 0 Carboxyltransferase domain, subdomain C and D Arrestin_N PF00339.29 ORY16280.1 - 2.9e-16 59.8 0.0 1.1e-15 58.0 0.0 2.0 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 ORY16280.1 - 1.1e-10 42.1 0.0 1.4e-06 28.8 0.0 2.6 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain SNF2_N PF00176.23 ORY16282.1 - 6.5e-64 215.8 0.0 1.2e-63 215.0 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-C3HC4_2 PF13923.6 ORY16282.1 - 3.6e-10 39.5 9.9 1.1e-09 38.0 9.9 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORY16282.1 - 2.8e-09 36.7 10.9 7.7e-09 35.3 10.9 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 ORY16282.1 - 5.4e-09 35.8 8.8 1e-08 34.9 8.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORY16282.1 - 2.5e-08 34.1 12.5 5.3e-08 33.1 12.5 1.6 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 ORY16282.1 - 1e-05 25.3 8.1 2.1e-05 24.3 8.1 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 ORY16282.1 - 6.9e-05 22.7 10.2 0.00014 21.8 10.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 ORY16282.1 - 0.0001 22.3 8.5 0.00028 20.8 8.5 1.8 1 0 0 1 1 1 1 RING-type zinc-finger Helicase_C PF00271.31 ORY16282.1 - 0.0001 22.6 0.0 0.00031 21.1 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-rbx1 PF12678.7 ORY16282.1 - 0.00014 22.1 13.7 0.00036 20.7 13.7 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 ORY16282.1 - 0.00047 20.3 9.2 0.00095 19.3 9.2 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 ORY16282.1 - 0.33 11.0 7.1 0.67 10.0 7.1 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Baculo_IE-1 PF05290.11 ORY16282.1 - 1.1 9.1 6.5 2.7 7.9 6.5 1.6 1 1 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) Zn_ribbon_17 PF17120.5 ORY16282.1 - 6.1 6.5 10.2 13 5.5 10.2 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type FmiP_Thoc5 PF09766.9 ORY16284.1 - 3.7e-21 75.8 15.2 6.2e-21 75.1 15.2 1.3 1 0 0 1 1 1 1 Fms-interacting protein/Thoc5 MMADHC PF10229.9 ORY16284.1 - 1.2 8.8 4.1 11 5.7 1.8 2.5 1 1 1 2 2 2 0 Methylmalonic aciduria and homocystinuria type D protein DUF2203 PF09969.9 ORY16286.1 - 0.029 15.1 1.4 11 6.8 0.0 2.6 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2203) SCAPER_N PF16501.5 ORY16286.1 - 0.23 11.5 0.9 0.82 9.7 0.1 2.2 2 1 1 3 3 3 0 S phase cyclin A-associated protein in the endoplasmic reticulum M20_dimer PF07687.14 ORY16289.1 - 1.2e-19 70.2 0.0 2.3e-19 69.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 ORY16289.1 - 3.1e-18 66.3 1.3 1.3e-16 60.9 1.3 2.2 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.17 ORY16289.1 - 1.4e-05 24.9 0.0 3e-05 23.8 0.0 1.5 2 0 0 2 2 2 1 Peptidase family M28 IL11 PF07400.11 ORY16289.1 - 0.69 9.5 4.7 0.18 11.4 1.4 1.7 2 0 0 2 2 2 0 Interleukin 11 eIF2_C PF09173.11 ORY16290.1 - 1.4e-34 118.2 0.3 3.4e-34 117.0 0.3 1.7 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 ORY16290.1 - 1.5e-22 80.1 0.3 1e-21 77.3 0.3 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 ORY16290.1 - 2.2e-12 47.2 0.2 4.8e-12 46.1 0.2 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 ORY16290.1 - 0.0044 17.1 0.0 0.0091 16.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ORY16290.1 - 0.025 14.5 0.1 0.3 11.0 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase INSIG PF07281.12 ORY16291.1 - 4.4e-75 252.0 0.8 6e-75 251.5 0.8 1.2 1 0 0 1 1 1 1 Insulin-induced protein (INSIG) LAT PF15234.6 ORY16291.1 - 0.053 13.3 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Linker for activation of T-cells AA_permease PF00324.21 ORY16292.1 - 3.9e-143 477.5 38.8 4.7e-143 477.3 38.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ORY16292.1 - 2.5e-39 135.3 41.1 3e-39 135.1 41.1 1.1 1 0 0 1 1 1 1 Amino acid permease DUF4781 PF16013.5 ORY16292.1 - 0.007 15.2 1.0 0.014 14.2 1.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4781) Pkinase PF00069.25 ORY16294.1 - 3.5e-65 220.0 0.0 4.8e-65 219.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY16294.1 - 2.1e-39 135.4 0.0 2.9e-39 134.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY16294.1 - 3e-07 30.0 0.0 2.4e-06 27.1 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 ORY16294.1 - 3.9e-05 22.8 0.0 3.9e-05 22.8 0.0 1.9 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 ORY16294.1 - 0.0013 18.7 4.7 0.066 13.1 0.1 3.1 2 1 1 3 3 3 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 ORY16294.1 - 0.12 11.4 0.0 0.18 10.8 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 ORY16294.1 - 0.24 10.7 0.0 0.24 10.7 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family NMO PF03060.15 ORY16296.1 - 2.2e-54 185.1 1.5 3.1e-54 184.6 1.5 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 ORY16296.1 - 3.4e-09 36.2 2.4 1.3e-08 34.2 2.4 1.9 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 ORY16296.1 - 0.0007 18.7 3.2 0.0011 18.0 3.2 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 ORY16296.1 - 0.098 11.8 2.3 0.17 11.0 2.3 1.2 1 0 0 1 1 1 0 Conserved region in glutamate synthase FATC PF02260.20 ORY16296.1 - 0.14 12.0 0.7 0.78 9.6 0.0 2.5 3 0 0 3 3 3 0 FATC domain Taxilin PF09728.9 ORY16297.1 - 2.8e-92 309.2 62.7 2.8e-92 309.2 62.7 1.4 2 0 0 2 2 2 1 Myosin-like coiled-coil protein PRIMA1 PF16101.5 ORY16297.1 - 4.6 7.3 7.3 0.58 10.2 1.5 2.2 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 M16C_assoc PF08367.11 ORY16298.1 - 1.2e-75 253.9 0.0 1.2e-75 253.9 0.0 1.7 2 0 0 2 2 2 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 ORY16298.1 - 5.1e-22 78.8 0.0 1.9e-16 60.6 0.0 2.7 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 ORY16298.1 - 0.0011 18.9 0.0 0.0053 16.7 0.0 2.2 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) TRI12 PF06609.13 ORY16299.1 - 2e-72 244.5 17.2 2.4e-72 244.3 17.2 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 ORY16299.1 - 5.5e-22 78.2 55.7 7.9e-21 74.4 54.9 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY16299.1 - 1.6e-10 40.5 7.9 1.6e-10 40.5 7.9 2.9 3 0 0 3 3 3 1 Sugar (and other) transporter HeLo PF14479.6 ORY16300.1 - 3.7e-36 124.9 0.1 9.1e-36 123.6 0.0 1.6 2 0 0 2 2 2 1 Prion-inhibition and propagation NDC10_II PF16787.5 ORY16300.1 - 0.0069 15.5 0.0 0.011 14.8 0.0 1.3 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 DUF2226 PF09987.9 ORY16300.1 - 0.046 13.1 0.0 0.094 12.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2226) ECH_1 PF00378.20 ORY16302.1 - 1.4e-70 237.5 0.0 1.7e-70 237.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ORY16302.1 - 3.6e-33 115.5 0.1 2.6e-30 106.1 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase AMP-binding PF00501.28 ORY16303.1 - 1.9e-71 240.9 0.0 1e-70 238.5 0.0 1.9 1 1 0 1 1 1 1 AMP-binding enzyme MFS_1 PF07690.16 ORY16304.1 - 2.6e-27 95.7 30.5 6e-27 94.5 26.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1772 PF08592.11 ORY16304.1 - 0.33 11.2 0.0 0.33 11.2 0.0 3.3 4 2 0 4 4 4 0 Domain of unknown function (DUF1772) DNA_pol_A_exo1 PF01612.20 ORY16305.1 - 1.9e-14 53.8 0.0 3e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease LSM PF01423.22 ORY16306.1 - 3.4e-19 68.3 0.2 3.7e-19 68.2 0.2 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 ORY16306.1 - 0.037 14.2 0.1 0.038 14.1 0.1 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain LSM14 PF12701.7 ORY16306.1 - 0.11 12.6 0.0 0.14 12.3 0.0 1.3 1 1 0 1 1 1 0 Scd6-like Sm domain HMG_box PF00505.19 ORY16308.1 - 4.2e-13 49.5 0.2 4.2e-13 49.5 0.2 1.8 2 0 0 2 2 2 1 HMG (high mobility group) box SAM_1 PF00536.30 ORY16308.1 - 2.2e-08 34.4 0.0 4.4e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) HMG_box_2 PF09011.10 ORY16308.1 - 3.1e-08 34.1 0.7 3.1e-08 34.1 0.7 1.9 2 0 0 2 2 2 1 HMG-box domain SAM_2 PF07647.17 ORY16308.1 - 0.00076 19.5 0.0 0.0017 18.4 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) NCD1 PF04904.13 ORY16308.1 - 0.18 11.8 0.1 0.79 9.8 0.1 2.0 2 1 0 2 2 2 0 NAB conserved region 1 (NCD1) 4HB_MCP_1 PF12729.7 ORY16308.1 - 3.7 7.0 5.5 2.3 7.7 1.3 2.0 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction DUF3074 PF11274.8 ORY16309.1 - 4.2e-42 144.2 0.1 5.6e-42 143.8 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) DXP_synthase_N PF13292.6 ORY16310.1 - 0.021 14.1 0.1 0.046 12.9 0.1 1.5 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase AA_permease PF00324.21 ORY16311.1 - 4.6e-109 365.2 43.0 5.7e-109 364.9 43.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ORY16311.1 - 7.8e-22 77.7 45.1 9.6e-22 77.4 45.1 1.0 1 0 0 1 1 1 1 Amino acid permease DUF5401 PF17380.2 ORY16313.1 - 0.0018 16.4 0.0 0.0022 16.2 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5401) F-box-like PF12937.7 ORY16313.1 - 0.029 14.3 0.0 0.1 12.5 0.0 1.9 2 0 0 2 2 2 0 F-box-like F-box PF00646.33 ORY16313.1 - 0.14 12.1 0.0 0.28 11.1 0.0 1.6 1 0 0 1 1 1 0 F-box domain Vint PF14623.6 ORY16313.1 - 1.7 8.5 2.8 51 3.6 2.4 2.2 1 1 1 2 2 2 0 Hint-domain IBR PF01485.21 ORY16314.1 - 0.013 15.8 3.1 0.013 15.8 3.1 2.1 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain zf-piccolo PF05715.13 ORY16314.1 - 1.1 9.5 7.2 5.2 7.3 4.7 2.4 2 0 0 2 2 2 0 Piccolo Zn-finger Vps36-NZF-N PF16988.5 ORY16315.1 - 1.1 8.7 4.5 0.24 10.8 0.7 1.8 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain MazG-like PF12643.7 ORY16317.1 - 1.4e-20 73.3 0.0 2.1e-20 72.8 0.0 1.3 1 0 0 1 1 1 1 MazG-like family MazG PF03819.17 ORY16317.1 - 2e-05 24.7 0.0 2.7e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 MazG nucleotide pyrophosphohydrolase domain dUTPase_2 PF08761.11 ORY16317.1 - 0.0057 16.8 0.0 0.0063 16.7 0.0 1.1 1 0 0 1 1 1 1 dUTPase DUF2075 PF09848.9 ORY16318.1 - 9.4e-61 206.1 0.0 1.2e-60 205.7 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 ORY16318.1 - 1.2e-07 31.8 0.0 2.5e-05 24.3 0.0 2.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit GIY-YIG PF01541.24 ORY16318.1 - 0.00016 21.9 0.0 0.00035 20.8 0.0 1.6 1 0 0 1 1 1 1 GIY-YIG catalytic domain AAA_22 PF13401.6 ORY16318.1 - 0.00042 20.6 0.3 0.0086 16.4 0.1 2.8 1 1 1 2 2 2 1 AAA domain AAA_11 PF13086.6 ORY16318.1 - 0.00098 19.0 0.0 0.0055 16.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 ORY16318.1 - 0.0022 18.4 0.2 0.009 16.4 0.2 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 ORY16318.1 - 0.0072 16.8 0.0 0.12 12.8 0.0 2.7 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) DEAD PF00270.29 ORY16318.1 - 0.01 15.6 0.0 0.56 10.0 0.0 2.7 1 1 1 2 2 2 0 DEAD/DEAH box helicase AAA_19 PF13245.6 ORY16318.1 - 0.016 15.6 0.0 0.048 14.0 0.0 1.8 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 ORY16318.1 - 0.02 14.3 0.0 0.036 13.5 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 ORY16318.1 - 0.043 14.4 0.0 0.15 12.6 0.0 2.0 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 ORY16318.1 - 0.065 13.1 0.5 1.1 9.1 0.1 2.8 2 1 1 3 3 3 0 NACHT domain GvpD PF07088.11 ORY16318.1 - 0.092 11.3 0.0 0.16 10.5 0.0 1.3 1 0 0 1 1 1 0 GvpD gas vesicle protein TniB PF05621.11 ORY16318.1 - 0.11 11.9 0.2 3.7 6.9 0.0 3.0 3 1 1 4 4 4 0 Bacterial TniB protein TIP49 PF06068.13 ORY16318.1 - 0.13 11.5 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain Nuc_deoxyri_tr2 PF15891.5 ORY16320.1 - 1.8e-34 118.3 0.0 2.4e-34 117.9 0.0 1.1 1 0 0 1 1 1 1 Nucleoside 2-deoxyribosyltransferase like Nuc_deoxyrib_tr PF05014.15 ORY16320.1 - 0.0029 17.6 0.0 0.0041 17.1 0.0 1.2 1 0 0 1 1 1 1 Nucleoside 2-deoxyribosyltransferase NACHT PF05729.12 ORY16324.1 - 3.9e-26 91.9 0.1 8.7e-26 90.8 0.1 1.6 1 0 0 1 1 1 1 NACHT domain WD40 PF00400.32 ORY16324.1 - 5.5e-11 42.8 0.6 2.2e-10 41.0 0.6 2.1 1 0 0 1 1 1 1 WD domain, G-beta repeat AAA_16 PF13191.6 ORY16324.1 - 3.4e-05 24.3 0.3 0.00017 22.1 0.1 2.3 2 0 0 2 2 2 1 AAA ATPase domain ANAPC4_WD40 PF12894.7 ORY16324.1 - 0.00051 20.3 0.0 0.0021 18.3 0.0 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ORY16324.1 - 0.0072 15.0 0.0 0.014 14.0 0.0 1.4 1 0 0 1 1 1 1 Nucleoporin Nup120/160 AAA_19 PF13245.6 ORY16324.1 - 0.0079 16.5 0.0 0.019 15.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain Ge1_WD40 PF16529.5 ORY16324.1 - 0.024 13.6 0.0 0.05 12.6 0.0 1.5 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein AAA_22 PF13401.6 ORY16324.1 - 0.039 14.2 0.0 0.1 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain HET PF06985.11 ORY16324.1 - 0.049 14.0 0.4 0.19 12.1 0.4 2.2 1 0 0 1 1 1 0 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.16 ORY16356.1 - 1.1e-30 106.8 40.5 1.2e-30 106.7 39.1 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Orf78 PF06024.12 ORY16356.1 - 0.028 14.7 0.0 0.061 13.6 0.0 1.5 1 0 0 1 1 1 0 Orf78 (ac78) SPRY PF00622.28 ORY16357.1 - 6e-19 68.3 0.1 9.9e-19 67.6 0.1 1.4 1 0 0 1 1 1 1 SPRY domain HEV_ORF1 PF02444.16 ORY16357.1 - 0.04 14.5 0.4 0.11 13.1 0.4 1.7 1 0 0 1 1 1 0 Hepatitis E virus ORF-2 (Putative capsid protein) HEAT_EZ PF13513.6 ORY16360.1 - 3.3e-26 91.3 11.6 4.1e-11 43.1 0.0 9.3 10 0 0 10 10 9 4 HEAT-like repeat HEAT PF02985.22 ORY16360.1 - 4.4e-23 79.4 8.3 0.00019 21.4 0.0 9.8 10 0 0 10 10 9 4 HEAT repeat HEAT_2 PF13646.6 ORY16360.1 - 1.2e-14 54.4 0.8 0.0035 17.7 0.0 6.6 5 2 2 7 7 7 3 HEAT repeats Cnd1 PF12717.7 ORY16360.1 - 5e-11 42.9 0.1 0.0066 16.5 0.0 4.7 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 ORY16360.1 - 1.2e-10 41.9 0.0 0.0056 17.2 0.0 5.9 6 1 2 8 8 8 3 Vacuolar 14 Fab1-binding region IBN_N PF03810.19 ORY16360.1 - 3.3e-07 30.1 0.0 1.4e-05 24.9 0.0 3.7 3 1 0 3 3 3 1 Importin-beta N-terminal domain Arm PF00514.23 ORY16360.1 - 0.00011 22.1 0.4 9.1 6.5 0.0 5.9 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat CLASP_N PF12348.8 ORY16360.1 - 0.00012 21.8 0.1 19 4.7 0.0 5.8 6 0 0 6 6 6 0 CLASP N terminal HEAT_PBS PF03130.16 ORY16360.1 - 0.0051 17.4 3.0 21 6.2 0.0 5.7 5 0 0 5 5 4 0 PBS lyase HEAT-like repeat RTP1_C1 PF10363.9 ORY16360.1 - 0.013 15.6 0.1 0.29 11.3 0.0 3.2 4 0 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 TAF6_C PF07571.13 ORY16360.1 - 0.013 15.8 0.1 17 5.8 0.0 4.2 3 1 0 4 4 3 0 TAF6 C-terminal HEAT repeat domain Xpo1 PF08389.12 ORY16360.1 - 0.017 15.2 0.2 0.88 9.6 0.0 3.7 4 1 0 4 4 4 0 Exportin 1-like protein DUF3437 PF11919.8 ORY16360.1 - 0.025 14.5 0.0 3.4 7.7 0.0 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3437) MMS19_C PF12460.8 ORY16360.1 - 0.1 11.7 4.2 17 4.4 0.0 4.5 6 1 0 6 6 6 0 RNAPII transcription regulator C-terminal Cohesin_HEAT PF12765.7 ORY16360.1 - 0.12 12.7 0.1 1.1e+02 3.2 0.0 4.2 5 0 0 5 5 5 0 HEAT repeat associated with sister chromatid cohesion Zn_clus PF00172.18 ORY16362.1 - 1.7e-08 34.4 12.1 2.7e-08 33.8 12.1 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 ORY16362.1 - 0.0001 21.3 0.9 0.00016 20.6 0.9 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Peptidase_C12 PF01088.21 ORY16363.1 - 3e-64 216.7 0.0 4.6e-63 212.8 0.0 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 ORY16363.1 - 8.7e-13 48.0 0.0 2.1e-12 46.8 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases YodL PF14191.6 ORY16363.1 - 0.057 14.3 0.0 0.23 12.3 0.0 1.9 2 0 0 2 2 2 0 YodL-like Pkinase PF00069.25 ORY16364.1 - 0.00016 21.2 0.0 0.00019 20.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.25 ORY16365.1 - 0.0074 15.7 0.0 0.01 15.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain TctB PF07331.11 ORY16366.1 - 1.9 8.8 11.6 0.092 13.0 0.9 2.5 2 1 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family DUF1772 PF08592.11 ORY16366.1 - 6.3 7.1 14.2 3.1 8.1 4.0 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF1772) Sigma70_r2 PF04542.14 ORY16367.1 - 0.077 12.8 0.1 0.24 11.2 0.1 1.8 1 0 0 1 1 1 0 Sigma-70 region 2 DUF3781 PF12636.7 ORY16367.1 - 0.085 12.7 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) Zn_clus PF00172.18 ORY16368.1 - 9.4e-06 25.7 11.3 1.7e-05 24.8 11.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cyclin_C PF02984.19 ORY16368.1 - 0.098 12.7 1.9 0.1 12.7 0.3 1.8 2 0 0 2 2 2 0 Cyclin, C-terminal domain AhpC-TSA PF00578.21 ORY16369.1 - 2.5e-28 98.5 0.0 3.3e-28 98.1 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 ORY16369.1 - 5.9e-19 68.2 0.0 1.1e-17 64.2 0.0 2.0 1 1 0 1 1 1 1 Redoxin DUF899 PF05988.12 ORY16369.1 - 0.022 14.3 0.0 0.028 13.9 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF899) AhpC-TSA_2 PF13911.6 ORY16369.1 - 0.098 12.8 0.0 0.19 11.8 0.0 1.6 1 1 0 1 1 1 0 AhpC/TSA antioxidant enzyme SeqA_N PF17206.3 ORY16372.1 - 0.04 13.2 0.4 2.7 7.4 0.1 2.6 2 0 0 2 2 2 0 SeqA protein N-terminal domain DUF4716 PF15837.5 ORY16372.1 - 0.6 10.2 3.3 2.5 8.3 1.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4716) Ribosomal_S13 PF00416.22 ORY16374.1 - 6.9e-55 184.9 2.5 8e-55 184.7 2.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 ORY16374.1 - 0.01 14.6 0.0 0.01 14.6 0.0 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) DUF2746 PF10874.8 ORY16374.1 - 0.038 14.4 0.0 0.057 13.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2746) CytochromB561_N PF09786.9 ORY16376.1 - 0.94 8.4 11.6 1.1 8.1 11.6 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal RGCC PF15151.6 ORY16376.1 - 6.2 7.1 10.1 2.9 8.1 7.4 1.8 1 1 1 2 2 2 0 Response gene to complement 32 protein family SBDS_C PF09377.10 ORY16377.1 - 3.6e-45 152.7 0.1 7.4e-45 151.7 0.0 1.5 2 0 0 2 2 2 1 SBDS protein C-terminal domain SBDS PF01172.18 ORY16377.1 - 8.3e-34 115.5 0.3 1.4e-33 114.8 0.3 1.4 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein K-cyclin_vir_C PF09080.10 ORY16377.1 - 0.12 12.8 0.0 0.29 11.6 0.0 1.7 1 0 0 1 1 1 0 K cyclin, C terminal Peptidase_S10 PF00450.22 ORY16378.1 - 5e-126 421.5 0.6 6.1e-126 421.2 0.6 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Carbpep_Y_N PF05388.11 ORY16378.1 - 4e-16 59.7 3.6 1.6e-15 57.8 3.6 1.9 1 1 0 1 1 1 1 Carboxypeptidase Y pro-peptide zf-Mss51 PF13824.6 ORY16379.1 - 4.1e-26 90.8 8.0 4.1e-26 90.8 8.0 1.9 2 0 0 2 2 2 1 Zinc-finger of mitochondrial splicing suppressor 51 DTW PF03942.15 ORY16379.1 - 0.095 12.4 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 DTW domain zf-MYND PF01753.18 ORY16379.1 - 0.72 10.0 5.6 0.2 11.8 2.0 1.9 2 0 0 2 2 2 0 MYND finger Cellulase PF00150.18 ORY16380.1 - 1.8e-15 57.2 0.1 3.9e-15 56.0 0.1 1.5 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) ENOD93 PF03386.14 ORY16380.1 - 0.086 12.7 0.0 0.26 11.2 0.0 1.8 1 0 0 1 1 1 0 Early nodulin 93 ENOD93 protein SKG6 PF08693.10 ORY16381.1 - 0.0041 16.5 0.0 0.0041 16.5 0.0 1.6 2 0 0 2 2 2 1 Transmembrane alpha-helix domain PAF-AH_p_II PF03403.13 ORY16382.1 - 2.5e-07 29.6 0.2 8.9e-07 27.7 0.2 1.8 1 1 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 ORY16382.1 - 4.5e-05 22.5 0.0 0.0035 16.3 0.0 2.3 2 0 0 2 2 2 2 Chlorophyllase enzyme PGAP1 PF07819.13 ORY16382.1 - 0.0022 17.8 0.1 0.028 14.2 0.1 2.2 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_1 PF00561.20 ORY16382.1 - 0.044 13.4 0.0 5.9 6.5 0.0 2.5 2 0 0 2 2 2 0 alpha/beta hydrolase fold Dus PF01207.17 ORY16383.1 - 7.1e-55 186.3 0.0 3.9e-54 183.9 0.0 2.1 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) BKACE PF05853.12 ORY16383.1 - 0.16 11.3 0.0 0.32 10.3 0.0 1.4 1 0 0 1 1 1 0 beta-keto acid cleavage enzyme FYVE PF01363.21 ORY16384.1 - 1.6e-14 53.8 10.3 2.4e-14 53.2 10.3 1.3 1 0 0 1 1 1 1 FYVE zinc finger GMC_oxred_N PF00732.19 ORY16385.1 - 2e-42 145.6 0.1 4.9e-42 144.3 0.1 1.6 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 ORY16385.1 - 2.1e-24 86.7 0.8 5.9e-24 85.2 0.0 2.1 2 1 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.24 ORY16385.1 - 1.5e-06 27.6 0.2 3.3e-06 26.4 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 ORY16385.1 - 4.3e-06 26.2 0.0 7.7e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORY16385.1 - 1.1e-05 25.6 0.2 3.8e-05 23.8 0.2 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 ORY16385.1 - 4.3e-05 22.9 0.0 7e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 ORY16385.1 - 0.00027 20.3 0.1 0.00048 19.5 0.1 1.3 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 ORY16385.1 - 0.00074 19.2 0.1 0.0048 16.5 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 ORY16385.1 - 0.0012 18.1 0.0 0.25 10.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ORY16385.1 - 0.0034 16.1 0.2 0.0057 15.4 0.2 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.7 ORY16385.1 - 0.012 15.0 0.3 0.017 14.5 0.3 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase ThiF PF00899.21 ORY16385.1 - 0.039 13.3 0.1 0.15 11.4 0.0 1.9 2 0 0 2 2 2 0 ThiF family GIDA PF01134.22 ORY16385.1 - 0.064 12.3 0.1 0.14 11.3 0.1 1.5 2 0 0 2 2 2 0 Glucose inhibited division protein A HET PF06985.11 ORY16386.1 - 2.8e-29 102.4 2.8 6.2e-28 98.0 2.8 2.0 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PPV_E2_C PF00511.17 ORY16386.1 - 0.023 14.9 0.2 0.059 13.5 0.1 1.8 2 0 0 2 2 2 0 E2 (early) protein, C terminal Acetyltransf_1 PF00583.25 ORY16387.1 - 9.2e-05 22.7 0.0 0.00038 20.7 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ORY16387.1 - 0.0094 15.9 0.0 0.2 11.6 0.0 2.6 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_5 PF13444.6 ORY16387.1 - 0.033 14.9 0.0 0.36 11.6 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ORY16387.1 - 0.12 12.8 0.0 0.35 11.3 0.0 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 ORY16387.1 - 0.18 12.0 0.0 0.52 10.5 0.0 1.7 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase Cu-oxidase_3 PF07732.15 ORY16389.1 - 5.6e-42 142.5 4.1 2.8e-41 140.3 1.7 2.9 2 1 1 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 ORY16389.1 - 3.4e-40 136.9 4.1 1.2e-37 128.7 0.2 3.7 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 ORY16389.1 - 1.5e-34 119.4 0.1 4.3e-34 117.9 0.1 1.8 1 0 0 1 1 1 1 Multicopper oxidase Pkinase PF00069.25 ORY16390.1 - 6.9e-30 104.3 0.0 1e-29 103.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY16390.1 - 3.5e-14 52.7 0.0 5.2e-14 52.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY16390.1 - 0.03 13.6 0.0 0.049 12.9 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Glyco_transf_25 PF01755.17 ORY16391.1 - 1.2e-10 41.6 0.0 6.4e-10 39.2 0.0 2.0 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) FAD_binding_3 PF01494.19 ORY16392.1 - 3.2e-11 43.1 2.1 1.3e-07 31.2 0.3 2.4 2 1 0 2 2 2 2 FAD binding domain Peptidase_S9 PF00326.21 ORY16392.1 - 0.04 13.4 0.0 0.072 12.6 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family NAD_binding_8 PF13450.6 ORY16392.1 - 0.095 12.9 0.0 0.23 11.7 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain XRCC4 PF06632.12 ORY16392.1 - 0.18 10.7 0.0 0.28 10.0 0.0 1.2 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 RTA1 PF04479.13 ORY16393.1 - 2.1e-64 217.0 7.5 2.8e-64 216.5 7.5 1.1 1 0 0 1 1 1 1 RTA1 like protein Fungal_trans_2 PF11951.8 ORY16394.1 - 3.5e-09 36.0 1.4 6.3e-09 35.1 1.3 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain NUC173 PF08161.12 ORY16394.1 - 0.012 15.3 0.0 0.022 14.4 0.0 1.4 1 0 0 1 1 1 0 NUC173 domain MFS_1 PF07690.16 ORY16395.1 - 1.5e-39 136.0 36.0 2.3e-32 112.3 30.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 ORY16395.1 - 0.004 16.1 1.1 0.004 16.1 1.1 2.1 1 1 1 2 2 2 1 MFS_1 like family Zn_clus PF00172.18 ORY16396.1 - 0.00069 19.7 2.2 0.00069 19.7 2.2 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Isochorismatase PF00857.20 ORY16397.1 - 5e-35 121.2 0.0 5.8e-35 121.0 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family zf-RING_2 PF13639.6 ORY16398.1 - 8e-10 38.9 8.5 1.4e-09 38.1 8.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 ORY16398.1 - 5.8e-06 26.5 7.0 5.8e-06 26.5 7.0 1.9 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 ORY16398.1 - 2.9e-05 23.8 5.1 2.9e-05 23.8 5.1 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORY16398.1 - 7.4e-05 22.7 9.6 0.00017 21.6 9.6 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 ORY16398.1 - 9.5e-05 22.5 6.0 0.00016 21.8 6.0 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 ORY16398.1 - 0.00023 21.0 6.8 0.00043 20.1 6.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORY16398.1 - 0.00063 19.7 7.0 0.0011 18.9 7.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 ORY16398.1 - 0.00073 19.5 4.7 0.0017 18.4 4.7 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 ORY16398.1 - 0.00093 19.0 7.3 0.026 14.4 8.1 2.3 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 ORY16398.1 - 0.0038 17.0 7.3 0.008 16.0 7.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Rad50_zn_hook PF04423.14 ORY16398.1 - 0.006 16.4 1.6 0.17 11.7 0.0 2.4 2 0 0 2 2 2 1 Rad50 zinc hook motif zf-RING_10 PF16685.5 ORY16398.1 - 0.29 11.3 3.9 0.57 10.4 3.9 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_11 PF17123.5 ORY16398.1 - 0.68 9.7 7.0 0.21 11.4 4.0 1.7 2 0 0 2 2 2 0 RING-like zinc finger Zn_ribbon_17 PF17120.5 ORY16398.1 - 1.2 8.8 8.2 1.2 8.8 6.0 2.2 2 1 0 2 2 2 0 Zinc-ribbon, C4HC2 type MFS_1 PF07690.16 ORY16399.1 - 5.2e-20 71.7 27.6 8.8e-18 64.3 26.1 2.5 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 ORY16399.1 - 0.0002 20.8 0.8 0.0002 20.8 0.8 2.2 2 1 1 3 3 3 1 Uncharacterised MFS-type transporter YbfB PhageP22-tail PF09251.10 ORY16400.1 - 0.0013 17.2 0.1 0.0052 15.2 0.1 1.8 2 0 0 2 2 2 1 Salmonella phage P22 tail-spike PRP1_N PF06424.12 ORY16400.1 - 0.0043 17.5 0.0 0.0078 16.6 0.0 1.3 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal zf-rbx1 PF12678.7 ORY16401.1 - 6.7e-07 29.5 2.5 1.4e-06 28.4 2.5 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 ORY16401.1 - 1.1e-06 28.8 4.6 9.5e-06 25.9 4.6 2.4 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 ORY16401.1 - 2.6e-05 24.0 3.4 5e-05 23.1 3.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 ORY16401.1 - 0.00018 21.3 1.8 0.00049 19.9 1.8 1.7 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 ORY16401.1 - 0.00042 20.3 0.0 0.0017 18.3 0.0 2.2 1 1 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 ORY16401.1 - 0.00064 19.7 1.4 0.0015 18.6 1.4 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 ORY16401.1 - 0.0025 17.7 3.2 0.0058 16.6 3.2 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 ORY16401.1 - 0.018 14.9 3.4 0.097 12.6 3.4 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 ORY16401.1 - 0.028 14.3 6.9 0.067 13.0 2.0 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 ORY16401.1 - 0.48 10.3 2.4 2.2 8.1 0.9 2.4 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 ORY16401.1 - 0.96 9.7 7.7 0.074 13.2 2.3 1.9 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING DUF1996 PF09362.10 ORY16402.1 - 2.4e-82 276.4 2.2 3e-82 276.1 2.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) zf-RING_2 PF13639.6 ORY16404.1 - 4.4e-10 39.7 3.2 6.7e-10 39.1 3.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 ORY16404.1 - 2.2e-09 37.2 0.8 3.2e-09 36.7 0.2 1.6 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 ORY16404.1 - 7.1e-06 25.9 1.6 1.2e-05 25.2 1.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 ORY16404.1 - 1.2e-05 25.0 1.2 0.00072 19.4 0.8 2.2 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 ORY16404.1 - 1.6e-05 25.1 2.4 3.6e-05 24.0 2.4 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 ORY16404.1 - 2.4e-05 24.1 2.4 4e-05 23.4 2.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 ORY16404.1 - 8.5e-05 22.5 0.4 0.00013 21.9 0.4 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 ORY16404.1 - 0.00016 21.4 2.8 0.00037 20.3 2.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 ORY16404.1 - 0.00029 20.6 1.6 0.00051 19.8 1.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.8 ORY16404.1 - 0.00069 19.4 1.4 0.0011 18.7 1.4 1.3 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.6 ORY16404.1 - 0.0015 18.6 5.4 0.0028 17.8 5.4 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.5 ORY16404.1 - 0.0023 17.7 2.1 0.0023 17.7 2.1 1.9 2 0 0 2 2 2 1 RING-like zinc finger FANCL_C PF11793.8 ORY16404.1 - 0.0053 16.9 1.0 0.039 14.1 0.2 2.1 2 0 0 2 2 2 1 FANCL C-terminal domain YdjO PF14169.6 ORY16404.1 - 0.065 13.0 0.9 0.3 10.9 0.0 2.2 2 0 0 2 2 2 0 Cold-inducible protein YdjO RINGv PF12906.7 ORY16404.1 - 0.066 13.4 1.1 0.13 12.4 1.1 1.5 1 0 0 1 1 1 0 RING-variant domain Zn-C2H2_12 PF18112.1 ORY16404.1 - 0.094 13.2 5.6 8 7.0 0.3 3.2 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain YacG PF03884.14 ORY16404.1 - 0.14 11.9 1.4 1.9 8.3 0.2 2.5 2 0 0 2 2 2 0 DNA gyrase inhibitor YacG Zn_ribbon_17 PF17120.5 ORY16404.1 - 0.44 10.2 2.6 1 9.0 2.5 1.8 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 ORY16404.1 - 0.57 10.0 4.1 1 9.2 4.1 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Sugar_tr PF00083.24 ORY16405.1 - 8.2e-77 259.0 29.7 9.8e-77 258.7 29.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY16405.1 - 2.8e-17 62.7 34.8 2.9e-17 62.7 32.8 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily Fungal_trans_2 PF11951.8 ORY16406.1 - 1.5e-08 33.9 0.0 1.9e-08 33.6 0.0 1.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY16406.1 - 4.7e-07 29.8 8.7 7.6e-07 29.2 8.7 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2306 PF10067.9 ORY16407.1 - 5.5e-16 59.1 7.7 5.5e-16 59.1 7.7 1.7 2 0 0 2 2 2 1 Predicted membrane protein (DUF2306) DUF2304 PF10066.9 ORY16407.1 - 4.3 7.6 14.5 1.9 8.8 0.9 3.8 4 0 0 4 4 4 0 Uncharacterized conserved protein (DUF2304) adh_short PF00106.25 ORY16408.1 - 2.3e-18 66.4 0.0 3.1e-18 65.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY16408.1 - 6e-12 45.6 0.1 8.3e-12 45.2 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY16408.1 - 0.0005 20.0 0.0 0.0011 18.9 0.0 1.6 1 1 0 1 1 1 1 KR domain Hydrolase_4 PF12146.8 ORY16413.1 - 0.16 11.2 0.0 0.29 10.4 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 SAP18 PF06487.12 ORY16414.1 - 2.9e-46 157.1 0.0 3.3e-46 157.0 0.0 1.0 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) Tubulin_3 PF14881.6 ORY16415.1 - 1.5e-75 252.9 0.1 3e-75 251.9 0.1 1.5 1 0 0 1 1 1 1 Tubulin domain Prp18 PF02840.15 ORY16415.1 - 2.4e-30 105.5 0.0 2.4e-30 105.5 0.0 2.1 2 0 0 2 2 2 1 Prp18 domain Misat_Tub_SegII PF10644.9 ORY16415.1 - 2.7e-21 76.0 0.1 2.1e-20 73.2 0.0 2.4 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain PRP4 PF08799.11 ORY16415.1 - 6e-10 38.5 1.1 6e-10 38.5 1.1 2.8 2 0 0 2 2 2 1 pre-mRNA processing factor 4 (PRP4) like Tubulin PF00091.25 ORY16415.1 - 0.016 15.4 0.0 0.04 14.1 0.0 1.6 1 0 0 1 1 1 0 Tubulin/FtsZ family, GTPase domain VIR_N PF15912.5 ORY16415.1 - 8.2 5.9 13.2 15 5.1 13.2 1.4 1 0 0 1 1 1 0 Virilizer, N-terminal Peptidase_M24 PF00557.24 ORY16418.1 - 1.6e-60 204.4 0.0 2.4e-60 203.8 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 ORY16418.1 - 4.7e-26 90.9 0.0 8.6e-26 90.1 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain OppC_N PF12911.7 ORY16421.1 - 5.2 7.1 10.9 2.2 8.3 0.1 4.0 4 0 0 4 4 4 0 N-terminal TM domain of oligopeptide transport permease C DUF1996 PF09362.10 ORY16423.1 - 6.8e-83 278.2 1.1 8.4e-83 277.9 1.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) HET PF06985.11 ORY16424.1 - 4.2e-24 85.6 0.0 1.1e-23 84.2 0.0 1.7 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.16 ORY16425.1 - 1.5e-34 119.5 28.4 1.5e-34 119.5 28.4 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 ORY16425.1 - 0.0043 16.8 1.9 0.01 15.5 1.9 1.6 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 Proton_antipo_C PF01010.19 ORY16425.1 - 0.032 13.9 0.3 0.091 12.4 0.1 1.8 1 1 0 2 2 2 0 NADH-dehyrogenase subunit F, TMs, (complex I) C-terminus Jagunal PF07086.12 ORY16425.1 - 0.19 11.8 2.9 0.92 9.6 0.5 2.7 2 1 0 2 2 2 0 Jagunal, ER re-organisation during oogenesis DUF4231 PF14015.6 ORY16425.1 - 0.62 10.6 5.8 30 5.2 0.1 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) PAC4 PF16093.5 ORY16426.1 - 1.4 9.2 6.6 1.8 8.8 5.1 1.8 2 0 0 2 2 2 0 Proteasome assembly chaperone 4 CoA_trans PF01144.23 ORY16427.1 - 3.1e-94 314.4 1.3 1.5e-55 188.0 0.1 2.0 2 0 0 2 2 2 2 Coenzyme A transferase Mal_decarbox_Al PF16957.5 ORY16427.1 - 0.0076 14.6 0.0 0.013 13.9 0.0 1.3 1 0 0 1 1 1 1 Malonate decarboxylase, alpha subunit, transporter AcetylCoA_hyd_C PF13336.6 ORY16427.1 - 0.022 14.7 0.5 0.076 13.0 0.0 2.0 2 0 0 2 2 2 0 Acetyl-CoA hydrolase/transferase C-terminal domain Zn_clus PF00172.18 ORY16428.1 - 1.1e-06 28.7 8.1 2.2e-06 27.7 8.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 4HBT_3 PF13622.6 ORY16429.1 - 1.9e-82 277.3 0.0 2.2e-82 277.0 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 ORY16429.1 - 7.6e-27 93.8 0.0 7.9e-13 48.4 0.0 4.1 3 1 0 3 3 3 3 Acyl-CoA thioesterase AMP-binding PF00501.28 ORY16430.1 - 1.9e-62 211.2 0.1 1.1e-32 113.2 0.0 3.9 2 2 0 2 2 2 2 AMP-binding enzyme DMAP_binding PF06464.11 ORY16430.1 - 2.5e-12 47.6 0.2 6.4e-12 46.3 0.2 1.6 1 0 0 1 1 1 1 DMAP1-binding Domain GvpG PF05120.12 ORY16430.1 - 0.0054 16.7 0.8 0.015 15.3 0.6 1.8 2 0 0 2 2 2 1 Gas vesicle protein G Ferric_reduct PF01794.19 ORY16431.1 - 1.8e-22 79.7 4.2 4.4e-22 78.5 4.2 1.7 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 ORY16431.1 - 1.7e-13 51.0 1.1 3.5e-09 36.9 0.0 2.6 2 1 1 3 3 3 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 ORY16431.1 - 4.9e-08 33.0 0.0 0.00039 20.5 0.0 2.5 2 0 0 2 2 2 2 FAD-binding domain HET PF06985.11 ORY16432.1 - 8.4e-19 68.4 0.2 1.1e-18 68.0 0.2 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Sugar_tr PF00083.24 ORY16433.1 - 3.5e-80 270.1 27.6 4.2e-80 269.8 27.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY16433.1 - 2.9e-26 92.3 45.7 1.2e-19 70.5 24.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 ORY16433.1 - 1.2e-06 27.2 1.5 1.2e-06 27.2 1.5 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 ORY16433.1 - 0.00015 20.2 9.9 0.00073 18.0 9.1 2.4 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family DUF3923 PF13061.6 ORY16434.1 - 0.35 11.0 0.2 0.35 11.0 0.2 4.5 6 0 0 6 6 6 0 Protein of unknown function (DUF3923) PIRT PF15099.6 ORY16434.1 - 0.52 9.9 2.5 0.83 9.2 0.2 2.2 1 1 1 2 2 2 0 Phosphoinositide-interacting protein family DUF2776 PF10951.8 ORY16435.1 - 0.012 14.9 0.7 0.021 14.1 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2776) PS_Dcarbxylase PF02666.15 ORY16436.1 - 2.7e-76 255.6 0.0 8.7e-76 253.9 0.0 1.7 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase Peptidase_M23 PF01551.22 ORY16436.1 - 0.16 12.2 0.2 4.9 7.4 0.1 2.4 2 0 0 2 2 2 0 Peptidase family M23 DUF2407 PF10302.9 ORY16437.1 - 7.1e-05 23.3 1.0 0.00049 20.6 0.0 2.8 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.23 ORY16437.1 - 0.00032 20.4 0.0 0.00066 19.4 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family MerR-DNA-bind PF09278.11 ORY16437.1 - 0.3 11.7 0.1 0.3 11.7 0.1 4.2 5 0 0 5 5 5 0 MerR, DNA binding ABC_tran PF00005.27 ORY16438.1 - 4.6e-42 143.8 0.0 4.1e-23 82.4 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 ORY16438.1 - 1.1e-28 100.7 36.0 6.4e-23 81.8 10.3 2.9 2 1 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 ORY16438.1 - 6.8e-11 42.0 2.1 0.011 15.2 0.0 4.3 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 ORY16438.1 - 3.6e-09 36.9 0.3 0.016 15.1 0.0 3.7 4 0 0 4 4 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 ORY16438.1 - 3.2e-07 31.1 0.2 0.0001 22.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 ORY16438.1 - 9.6e-07 28.5 0.5 0.0027 17.4 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 ORY16438.1 - 1.1e-06 29.0 0.1 0.011 16.1 0.0 3.1 2 1 0 2 2 2 2 AAA domain T2SSE PF00437.20 ORY16438.1 - 2.6e-06 26.7 0.0 0.00051 19.2 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein RsgA_GTPase PF03193.16 ORY16438.1 - 4.3e-06 26.7 0.1 0.0044 17.0 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 ORY16438.1 - 6.9e-06 26.6 0.1 0.0059 17.0 0.0 3.0 2 0 0 2 2 2 1 AAA ATPase domain DUF87 PF01935.17 ORY16438.1 - 5.9e-05 23.3 0.3 0.026 14.6 0.0 2.4 2 0 0 2 2 2 1 Helicase HerA, central domain Pox_A32 PF04665.12 ORY16438.1 - 0.00013 21.5 0.2 0.047 13.1 0.1 2.6 2 0 0 2 2 2 1 Poxvirus A32 protein AAA_25 PF13481.6 ORY16438.1 - 0.00016 21.3 0.1 0.62 9.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 ORY16438.1 - 0.0004 20.3 0.0 0.077 12.9 0.0 2.6 2 0 0 2 2 2 1 NACHT domain MMR_HSR1 PF01926.23 ORY16438.1 - 0.00041 20.4 0.0 0.61 10.2 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 ORY16438.1 - 0.0005 19.5 0.0 1.1 8.5 0.0 2.6 2 0 0 2 2 2 2 FtsK/SpoIIIE family IstB_IS21 PF01695.17 ORY16438.1 - 0.00069 19.4 0.6 2 8.1 0.0 3.4 3 0 0 3 3 3 1 IstB-like ATP binding protein NB-ARC PF00931.22 ORY16438.1 - 0.001 18.3 0.0 0.034 13.3 0.0 2.9 2 1 0 2 2 2 1 NB-ARC domain AAA_24 PF13479.6 ORY16438.1 - 0.0011 18.8 0.0 0.56 9.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 ORY16438.1 - 0.0015 18.7 0.0 0.61 10.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 ORY16438.1 - 0.0029 17.1 0.0 1.3 8.5 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region Dynamin_N PF00350.23 ORY16438.1 - 0.0039 17.3 0.2 0.31 11.1 0.0 2.4 2 0 0 2 2 2 1 Dynamin family cobW PF02492.19 ORY16438.1 - 0.0057 16.3 0.8 0.17 11.4 0.1 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.15 ORY16438.1 - 0.0062 16.5 2.5 1.3 8.9 0.0 3.2 3 0 0 3 3 3 1 NTPase AAA_30 PF13604.6 ORY16438.1 - 0.0063 16.3 0.5 0.53 10.0 0.0 3.1 3 0 0 3 3 3 1 AAA domain Roc PF08477.13 ORY16438.1 - 0.01 16.0 0.5 6.1 7.1 0.0 2.9 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_5 PF07728.14 ORY16438.1 - 0.012 15.6 0.3 15 5.6 0.1 3.5 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) TrwB_AAD_bind PF10412.9 ORY16438.1 - 0.012 14.5 0.1 0.71 8.7 0.0 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_15 PF13175.6 ORY16438.1 - 0.013 15.2 0.3 2.8 7.6 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_11 PF13086.6 ORY16438.1 - 0.023 14.5 0.0 7.3 6.3 0.0 2.7 2 1 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 ORY16438.1 - 0.038 13.9 0.0 0.58 10.0 0.0 2.6 3 0 0 3 3 2 0 ATPase domain predominantly from Archaea Viral_helicase1 PF01443.18 ORY16438.1 - 0.039 13.7 0.2 2.5 7.8 0.0 2.8 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase AAA_18 PF13238.6 ORY16438.1 - 0.041 14.4 0.0 7.4 7.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 ORY16438.1 - 0.044 14.1 2.6 0.99 9.7 0.0 3.5 4 0 0 4 4 3 0 AAA domain AAA PF00004.29 ORY16438.1 - 0.044 14.2 0.0 22 5.5 0.0 3.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 ORY16438.1 - 0.057 13.8 0.1 7 7.1 0.0 2.6 2 0 0 2 2 2 0 RNA helicase MobB PF03205.14 ORY16438.1 - 0.059 13.3 0.2 3.6 7.5 0.0 2.7 3 0 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B ATP_bind_1 PF03029.17 ORY16438.1 - 0.083 12.7 0.4 10 5.8 0.0 2.8 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein SbcCD_C PF13558.6 ORY16438.1 - 0.13 12.5 3.3 5.4 7.3 0.1 3.6 3 1 0 3 3 2 0 Putative exonuclease SbcCD, C subunit Mg_chelatase PF01078.21 ORY16438.1 - 0.18 11.2 0.0 3.7 6.9 0.0 2.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DEAD PF00270.29 ORY16438.1 - 0.21 11.4 0.5 15 5.3 0.0 2.9 3 0 0 3 3 3 0 DEAD/DEAH box helicase Fungal_trans_2 PF11951.8 ORY16439.1 - 1.8e-15 56.6 0.8 2.4e-15 56.2 0.8 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY16439.1 - 0.00072 19.6 1.7 0.0015 18.7 1.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Amino_oxidase PF01593.24 ORY16440.1 - 1.2e-13 51.2 0.0 1.3e-13 51.1 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase zf-C3HC4_3 PF13920.6 ORY16441.1 - 4.7 7.1 7.2 0.26 11.2 2.0 1.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) AA_permease_2 PF13520.6 ORY16443.1 - 3.5e-60 204.0 51.0 4.5e-60 203.7 51.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ORY16443.1 - 1.7e-15 56.6 41.1 2.2e-15 56.2 41.1 1.1 1 0 0 1 1 1 1 Amino acid permease His_Phos_2 PF00328.22 ORY16444.1 - 2.4e-63 214.8 0.0 2.8e-63 214.6 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Med3 PF11593.8 ORY16445.1 - 0.18 11.0 4.7 0.26 10.4 4.7 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Reo_sigma1 PF01664.16 ORY16448.1 - 2.9 7.1 6.6 0.11 11.8 0.3 1.8 2 0 0 2 2 2 0 Reovirus viral attachment protein sigma 1 RPE65 PF03055.15 ORY16449.1 - 4.3e-110 369.1 0.0 4.9e-110 368.9 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Presenilin PF01080.17 ORY16450.1 - 2.9 6.5 4.4 3.6 6.3 4.4 1.1 1 0 0 1 1 1 0 Presenilin ERM PF00769.19 ORY16450.1 - 5.7 6.7 30.9 8.5 6.1 30.9 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Ribosomal_S7 PF00177.21 ORY16451.1 - 2e-36 124.9 1.8 2.4e-36 124.6 1.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e DUF4672 PF15716.5 ORY16452.1 - 0.0021 17.7 0.2 0.0021 17.7 0.2 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4672) Baculo_PEP_C PF04513.12 ORY16452.1 - 0.37 10.8 3.8 0.79 9.8 1.4 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ZnuA PF01297.17 ORY16452.1 - 5.1 6.4 10.8 1.1 8.5 1.5 3.0 1 1 2 3 3 3 0 Zinc-uptake complex component A periplasmic zf-MYND PF01753.18 ORY16453.1 - 2.7e-05 24.2 6.2 5.3e-05 23.2 6.2 1.5 1 0 0 1 1 1 1 MYND finger Hemerythrin PF01814.23 ORY16455.1 - 5.1e-09 36.9 0.0 6.6e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Iso_dh PF00180.20 ORY16457.1 - 3e-122 408.1 0.0 3.4e-122 407.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase KGG PF10685.9 ORY16458.1 - 3.2e-24 84.4 18.5 8.5e-11 41.8 1.0 3.1 3 0 0 3 3 3 3 Stress-induced bacterial acidophilic repeat motif MMS1_N PF10433.9 ORY16460.1 - 2.2e-100 336.6 0.0 3.2e-100 336.1 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 ORY16460.1 - 1.5e-86 290.7 0.0 5.1e-86 288.9 0.0 1.9 2 1 0 2 2 2 1 CPSF A subunit region Imm-NTF2-2 PF15631.6 ORY16460.1 - 0.073 13.3 0.0 0.21 11.8 0.0 1.8 1 0 0 1 1 1 0 NTF2 fold immunity protein DUF1131 PF06572.12 ORY16460.1 - 0.085 12.6 0.0 0.23 11.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1131) OST3_OST6 PF04756.13 ORY16462.1 - 0.041 13.2 1.4 0.042 13.2 0.1 1.6 2 0 0 2 2 2 0 OST3 / OST6 family, transporter family Claudin_2 PF13903.6 ORY16462.1 - 0.17 11.7 5.0 0.12 12.2 2.8 1.9 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Sulfotransfer_3 PF13469.6 ORY16463.1 - 0.0023 18.3 0.0 0.41 11.0 0.0 3.1 2 1 0 2 2 2 1 Sulfotransferase family Methyltr_RsmB-F PF01189.17 ORY16465.1 - 5.5e-19 68.6 0.1 5.3e-13 49.1 0.0 2.4 2 0 0 2 2 2 2 16S rRNA methyltransferase RsmB/F Protein_K PF12283.8 ORY16465.1 - 0.25 11.6 1.2 0.68 10.2 0.2 2.2 3 0 0 3 3 3 0 Bacteriophage protein K Tyrosinase PF00264.20 ORY16466.1 - 5.5e-55 187.1 0.1 9.2e-55 186.3 0.1 1.4 1 0 0 1 1 1 1 Common central domain of tyrosinase Tyosinase_C PF18132.1 ORY16466.1 - 5.7e-35 120.6 0.0 9.4e-35 119.9 0.0 1.4 1 0 0 1 1 1 1 Tyosinase C-terminal domain Pyr_redox_2 PF07992.14 ORY16467.1 - 1.1e-53 182.4 0.0 1.4e-53 182.0 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORY16467.1 - 2.4e-21 76.1 0.8 6.9e-17 61.8 0.0 3.4 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Rhodanese PF00581.20 ORY16467.1 - 8e-10 39.2 0.0 4.9e-09 36.7 0.0 2.2 2 1 1 3 3 3 1 Rhodanese-like domain NAD_binding_8 PF13450.6 ORY16467.1 - 4.4e-07 30.0 2.4 0.0018 18.5 0.5 3.0 3 0 0 3 3 3 2 NAD(P)-binding Rossmann-like domain Pyr_redox_dim PF02852.22 ORY16467.1 - 8.5e-06 26.0 0.3 2.6e-05 24.4 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_3 PF13738.6 ORY16467.1 - 2.3e-05 23.8 0.0 8.3e-05 22.0 0.0 2.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ORY16467.1 - 0.00022 20.0 1.9 0.61 8.7 0.3 4.0 3 1 1 4 4 4 1 HI0933-like protein AlaDh_PNT_C PF01262.21 ORY16467.1 - 0.0083 15.4 0.1 0.027 13.7 0.0 1.9 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 ORY16467.1 - 0.038 13.1 3.4 3.6 6.6 0.1 3.4 4 0 0 4 4 4 0 FAD binding domain NAD_binding_9 PF13454.6 ORY16467.1 - 0.074 13.0 1.9 19 5.2 0.0 3.5 4 0 0 4 4 4 0 FAD-NAD(P)-binding DAO PF01266.24 ORY16467.1 - 0.091 12.3 6.2 1.7 8.1 0.1 3.8 3 1 1 4 4 4 0 FAD dependent oxidoreductase 3HCDH_N PF02737.18 ORY16467.1 - 0.17 11.7 0.0 0.35 10.7 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Arf PF00025.21 ORY16468.1 - 2.2e-41 141.2 0.0 8.2e-26 90.5 0.0 2.0 2 0 0 2 2 2 2 ADP-ribosylation factor family G-alpha PF00503.20 ORY16468.1 - 5e-13 48.9 0.0 4.8e-07 29.3 0.0 2.0 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 ORY16468.1 - 3.9e-12 46.1 0.0 5e-08 32.7 0.0 2.1 2 0 0 2 2 2 2 Ras family Roc PF08477.13 ORY16468.1 - 2.5e-11 43.8 0.0 7.7e-11 42.3 0.0 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 ORY16468.1 - 3.3e-07 29.9 0.0 4e-07 29.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 ORY16468.1 - 5e-07 29.3 0.0 1.4e-05 24.7 0.0 2.0 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 ORY16468.1 - 1.2e-05 25.0 0.0 0.0025 17.4 0.0 2.1 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 ORY16468.1 - 7.3e-05 22.8 0.0 0.00011 22.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF4630 PF15443.6 ORY16468.1 - 0.011 15.9 0.0 0.021 15.0 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4630) Thymidylate_kin PF02223.17 ORY16468.1 - 0.1 12.2 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Thymidylate kinase TniB PF05621.11 ORY16468.1 - 0.13 11.7 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein FeoB_N PF02421.18 ORY16468.1 - 0.16 11.5 0.0 0.31 10.6 0.0 1.6 2 0 0 2 2 2 0 Ferrous iron transport protein B AT_hook PF02178.19 ORY16469.1 - 0.51 10.4 6.1 1.1 9.4 6.1 1.5 1 0 0 1 1 1 0 AT hook motif Gtr1_RagA PF04670.12 ORY16470.1 - 5.6e-71 238.6 0.2 7.1e-71 238.2 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 ORY16470.1 - 9.9e-06 25.1 0.0 1.4e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 ORY16470.1 - 0.00047 19.8 0.0 0.00075 19.1 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 ORY16470.1 - 0.00089 19.3 0.0 0.0021 18.1 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase Roc PF08477.13 ORY16470.1 - 0.028 14.6 0.0 0.051 13.8 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_14 PF13173.6 ORY16470.1 - 0.03 14.4 0.0 0.087 12.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 ORY16470.1 - 0.059 13.8 0.0 0.18 12.2 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain SRPRB PF09439.10 ORY16470.1 - 0.069 12.6 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit FAST_1 PF06743.15 ORY16470.1 - 0.099 12.6 0.1 0.24 11.4 0.1 1.6 1 0 0 1 1 1 0 FAST kinase-like protein, subdomain 1 Sp38 PF07354.12 ORY16470.1 - 0.13 11.7 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 Zona-pellucida-binding protein (Sp38) Cyt-b5 PF00173.28 ORY16471.1 - 1.3e-10 41.3 0.0 1.7e-10 40.9 0.0 1.4 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF2235 PF09994.9 ORY16472.1 - 6.2e-78 262.1 0.0 8e-78 261.7 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) DUF2183 PF09949.9 ORY16473.1 - 7.3e-34 116.1 0.0 4.7e-33 113.5 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2183) GAT PF03127.14 ORY16474.1 - 1.1e-18 67.3 0.3 2.2e-18 66.3 0.2 1.6 2 0 0 2 2 2 1 GAT domain VHS PF00790.19 ORY16474.1 - 0.0033 17.3 0.0 0.006 16.4 0.0 1.4 1 0 0 1 1 1 1 VHS domain BTB_2 PF02214.22 ORY16476.1 - 1.2e-05 25.5 0.1 0.0031 17.8 0.0 2.3 2 0 0 2 2 2 2 BTB/POZ domain GST_N PF02798.20 ORY16477.1 - 4.4e-13 49.4 0.1 8.5e-13 48.5 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 ORY16477.1 - 2.6e-11 43.6 0.0 5.5e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 ORY16477.1 - 8.6e-09 35.7 0.0 3e-08 34.0 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 ORY16477.1 - 5e-08 32.9 0.0 8.9e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 ORY16477.1 - 8.6e-08 32.4 0.0 2e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 ORY16477.1 - 8.1e-07 29.2 0.0 1.6e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 ORY16477.1 - 0.0027 18.3 0.0 0.0049 17.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain NDUF_B4 PF07225.12 ORY16478.1 - 0.0014 18.6 0.0 0.0014 18.6 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) OGFr_N PF04664.13 ORY16479.1 - 3.6e-18 65.8 0.1 1.4e-11 44.3 0.0 2.1 2 0 0 2 2 2 2 Opioid growth factor receptor (OGFr) conserved region SOG2 PF10428.9 ORY16479.1 - 0.44 9.7 6.5 0.58 9.3 6.5 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Alpha-amylase PF00128.24 ORY16480.1 - 5e-25 88.8 3.4 2.3e-24 86.6 3.4 1.8 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.16 ORY16480.1 - 0.00049 18.5 0.7 2.7 6.1 0.0 3.0 3 0 0 3 3 3 3 Glycosyl hydrolase family 70 Mito_carr PF00153.27 ORY16481.1 - 3.1e-42 142.4 9.2 3.4e-16 58.9 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein NDUF_B12 PF08122.12 ORY16481.1 - 0.16 12.1 0.0 0.65 10.1 0.0 2.1 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B12 subunit family MFS_1 PF07690.16 ORY16483.1 - 6.4e-14 51.6 11.7 6.4e-14 51.6 11.7 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY16483.1 - 0.00042 19.3 6.8 0.00042 19.3 6.8 2.8 2 2 0 2 2 2 1 Sugar (and other) transporter adh_short_C2 PF13561.6 ORY16485.1 - 2.2e-42 145.2 0.0 3.1e-42 144.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY16485.1 - 6e-40 136.8 0.0 7.6e-40 136.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORY16485.1 - 4.1e-10 39.9 0.1 7.5e-10 39.0 0.1 1.5 1 1 0 1 1 1 1 KR domain UBX PF00789.20 ORY16487.1 - 1.7e-12 47.4 0.0 3.6e-12 46.3 0.0 1.6 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.6 ORY16487.1 - 6.5e-11 41.9 0.1 1.4e-10 40.8 0.1 1.6 1 0 0 1 1 1 1 UBA-like domain SUB1_ProdP9 PF18213.1 ORY16487.1 - 0.056 13.3 0.1 0.16 11.9 0.1 1.7 1 0 0 1 1 1 0 SUB1 protease Prodomain ProdP9 DUF1682 PF07946.14 ORY16487.1 - 0.056 12.6 4.8 0.099 11.8 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DDRGK PF09756.9 ORY16487.1 - 0.11 12.0 14.4 0.2 11.2 14.4 1.3 1 0 0 1 1 1 0 DDRGK domain EST1_DNA_bind PF10373.9 ORY16488.1 - 1.4e-63 215.0 0.1 2e-63 214.5 0.1 1.2 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.9 ORY16488.1 - 1.5e-19 71.0 3.5 2.9e-19 70.1 2.0 2.1 2 0 0 2 2 2 1 Telomerase activating protein Est1 TPR_17 PF13431.6 ORY16488.1 - 0.12 12.8 0.0 0.39 11.2 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat RNA_pol_3_Rpc31 PF11705.8 ORY16489.1 - 0.0037 17.6 6.8 0.0058 16.9 6.8 1.4 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 Myc_N PF01056.18 ORY16489.1 - 0.012 15.6 3.0 0.012 15.6 3.0 1.7 2 0 0 2 2 2 0 Myc amino-terminal region Nop14 PF04147.12 ORY16489.1 - 0.012 13.8 7.4 0.014 13.6 7.4 1.1 1 0 0 1 1 1 0 Nop14-like family Pox_Ag35 PF03286.14 ORY16489.1 - 0.012 15.4 4.3 0.012 15.4 4.3 1.6 2 0 0 2 2 2 0 Pox virus Ag35 surface protein RXT2_N PF08595.11 ORY16489.1 - 0.021 14.8 3.7 0.038 14.0 3.7 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal zf-C2H2 PF00096.26 ORY16489.1 - 0.033 14.7 10.3 0.32 11.5 0.3 3.6 3 0 0 3 3 3 0 Zinc finger, C2H2 type Cwf_Cwc_15 PF04889.12 ORY16489.1 - 0.091 12.5 8.5 0.14 11.9 8.5 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF4746 PF15928.5 ORY16489.1 - 0.2 11.1 2.9 0.29 10.5 2.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) PPP4R2 PF09184.11 ORY16489.1 - 0.32 10.6 11.5 0.5 9.9 11.5 1.2 1 0 0 1 1 1 0 PPP4R2 DUF2457 PF10446.9 ORY16489.1 - 0.39 9.8 15.5 0.68 9.0 15.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF913 PF06025.12 ORY16489.1 - 0.56 9.1 1.5 0.82 8.6 1.5 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) BUD22 PF09073.10 ORY16489.1 - 0.84 8.9 9.8 1.5 8.1 9.8 1.3 1 0 0 1 1 1 0 BUD22 FAM176 PF14851.6 ORY16489.1 - 0.9 9.2 8.1 2.2 7.9 8.1 1.7 1 0 0 1 1 1 0 FAM176 family Sigma70_ner PF04546.13 ORY16489.1 - 1.1 9.1 9.8 1.9 8.3 9.8 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region zf-C2H2_4 PF13894.6 ORY16489.1 - 1.3 10.0 11.9 12 7.1 0.3 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger RPN2_C PF18004.1 ORY16489.1 - 1.7 8.5 5.1 3.1 7.7 5.1 1.4 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain CDC45 PF02724.14 ORY16489.1 - 3.9 5.6 10.5 5.4 5.2 10.5 1.1 1 0 0 1 1 1 0 CDC45-like protein PBP1_TM PF14812.6 ORY16489.1 - 4.6 7.7 13.0 13 6.3 13.0 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TFB6 PF17110.5 ORY16489.1 - 5.4 6.7 5.9 8.6 6.1 5.9 1.3 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH SDA1 PF05285.12 ORY16489.1 - 5.4 6.3 13.5 8 5.8 13.5 1.2 1 0 0 1 1 1 0 SDA1 DNA_pol_phi PF04931.13 ORY16489.1 - 7.2 4.6 19.5 9.8 4.1 19.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi PfkB PF00294.24 ORY16490.1 - 1e-73 248.3 0.1 1.2e-73 248.1 0.1 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 ORY16490.1 - 1.2e-05 24.8 0.0 2e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PhoPQ_related PF10142.9 ORY16490.1 - 0.16 10.6 0.0 0.23 10.1 0.0 1.1 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein Pan3_PK PF18101.1 ORY16491.1 - 1.4e-54 183.8 0.0 4.7e-54 182.1 0.0 1.8 1 1 0 1 1 1 1 Pan3 Pseudokinase domain Pkinase PF00069.25 ORY16491.1 - 8.8e-06 25.3 0.0 1.4e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain zf-CCCH PF00642.24 ORY16491.1 - 0.0045 16.9 1.0 0.0082 16.0 1.0 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) NUFIP2 PF15293.6 ORY16491.1 - 0.11 11.4 1.2 0.17 10.7 1.2 1.2 1 0 0 1 1 1 0 Nuclear fragile X mental retardation-interacting protein 2 Glyco_trans_2_3 PF13632.6 ORY16516.1 - 5e-53 179.9 2.4 5e-53 179.9 2.4 2.5 1 1 1 2 2 2 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 ORY16516.1 - 0.0013 18.2 0.0 0.0026 17.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 ORY16516.1 - 0.0017 18.2 0.0 0.017 14.9 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 ORY16516.1 - 0.0025 17.8 0.0 0.0045 16.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_hydro_16 PF00722.21 ORY16517.1 - 2.2e-18 66.4 0.5 3.7e-18 65.6 0.5 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 ATPase_gene1 PF09527.10 ORY16517.1 - 0.033 14.3 1.0 1.1 9.5 0.1 2.5 2 0 0 2 2 2 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter Arabinose_trans PF04602.12 ORY16517.1 - 0.27 10.0 1.1 0.54 9.0 0.1 1.7 2 0 0 2 2 2 0 Mycobacterial cell wall arabinan synthesis protein WSC PF01822.19 ORY16519.1 - 7.9e-11 42.0 2.6 9.3e-11 41.8 2.6 1.1 1 0 0 1 1 1 1 WSC domain WSC PF01822.19 ORY16520.1 - 2.1e-46 156.0 52.9 5.8e-17 61.7 9.5 4.3 4 0 0 4 4 4 3 WSC domain Glyoxal_oxid_N PF07250.11 ORY16520.1 - 2.5e-26 92.3 0.0 3.8e-25 88.5 0.0 2.6 3 0 0 3 3 3 1 Glyoxal oxidase N-terminus DUF1929 PF09118.11 ORY16520.1 - 9.5e-20 70.7 0.0 1.9e-19 69.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) GLEYA PF10528.9 ORY16520.1 - 0.12 12.9 0.1 18 5.8 0.0 3.1 3 0 0 3 3 3 0 GLEYA domain FAD_binding_4 PF01565.23 ORY16521.1 - 2.6e-15 56.4 0.9 3.7e-15 55.9 0.9 1.2 1 0 0 1 1 1 1 FAD binding domain ALO PF04030.14 ORY16521.1 - 6.8e-10 39.2 0.2 3.9e-06 26.9 0.0 2.5 2 1 0 2 2 2 2 D-arabinono-1,4-lactone oxidase FAD_binding_5 PF00941.21 ORY16521.1 - 0.082 12.6 0.4 0.18 11.5 0.4 1.5 1 1 0 1 1 1 0 FAD binding domain in molybdopterin dehydrogenase Abhydrolase_3 PF07859.13 ORY16522.1 - 7.8e-23 81.4 0.1 1.1e-22 80.9 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 ORY16522.1 - 2.8e-14 52.8 0.0 3.7e-14 52.4 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_6 PF12697.7 ORY16522.1 - 0.0034 18.0 0.5 0.0066 17.1 0.5 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORY16522.1 - 0.05 12.9 0.0 0.09 12.0 0.0 1.4 1 1 0 1 1 1 0 Serine aminopeptidase, S33 Pyr_redox_2 PF07992.14 ORY16523.1 - 6.2e-21 74.9 0.0 8.3e-21 74.5 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORY16523.1 - 1e-05 26.0 0.0 0.00041 20.9 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Acyl-CoA_dh_1 PF00441.24 ORY16524.1 - 8.5e-39 133.2 4.4 1.5e-38 132.3 4.4 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 ORY16524.1 - 1.4e-31 109.5 0.1 3.3e-31 108.3 0.1 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 ORY16524.1 - 2.6e-23 82.0 0.0 6.3e-23 80.8 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 ORY16524.1 - 1.7e-15 57.5 0.6 2.7e-15 56.8 0.6 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 ORY16524.1 - 0.00051 19.8 0.1 0.0012 18.5 0.1 1.6 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal AgrD PF05931.11 ORY16524.1 - 0.019 15.0 0.0 0.075 13.1 0.0 2.0 1 0 0 1 1 1 0 Staphylococcal AgrD protein SBP PF03110.14 ORY16526.1 - 0.01 16.1 2.9 0.021 15.1 2.9 1.5 1 0 0 1 1 1 0 SBP domain DUF3429 PF11911.8 ORY16526.1 - 0.069 13.4 4.1 0.76 10.1 1.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3429) Arrestin_N PF00339.29 ORY16527.1 - 2.5e-07 30.9 0.0 5.2e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Bul1_N PF04425.12 ORY16527.1 - 5e-06 25.5 0.1 5e-06 25.5 0.1 1.7 2 1 0 2 2 2 1 Bul1 N terminus Bul1_C PF04426.12 ORY16527.1 - 1.2e-05 24.8 0.0 1.9e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Bul1 C terminus AA_permease_2 PF13520.6 ORY16528.1 - 2e-42 145.5 48.1 2.4e-42 145.3 48.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ORY16528.1 - 7.8e-21 74.2 41.3 1.1e-20 73.8 41.3 1.1 1 0 0 1 1 1 1 Amino acid permease GA-like PF17573.2 ORY16529.1 - 0.031 14.2 1.7 0.12 12.3 0.3 2.2 2 0 0 2 2 2 0 GA-like domain zf-RING_2 PF13639.6 ORY16530.1 - 8.6e-13 48.4 4.6 1.2e-12 48.0 4.6 1.2 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 ORY16530.1 - 6.4e-11 41.9 2.4 8.9e-11 41.5 2.4 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 ORY16530.1 - 6.8e-09 35.3 2.4 1.2e-08 34.5 2.4 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 ORY16530.1 - 1.1e-08 34.8 1.1 1.6e-08 34.3 1.1 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORY16530.1 - 1.5e-07 31.3 0.4 5.5e-07 29.5 0.4 1.9 1 1 1 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 ORY16530.1 - 5.2e-07 29.8 6.9 1.5e-06 28.4 6.9 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 ORY16530.1 - 7.8e-07 28.9 1.5 1e-06 28.5 1.5 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORY16530.1 - 3.8e-06 26.8 1.4 5.3e-06 26.3 1.4 1.2 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 ORY16530.1 - 7.4e-06 25.7 1.3 1.3e-05 25.0 1.3 1.4 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 ORY16530.1 - 5.2e-05 22.8 4.0 8e-05 22.2 4.0 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_6 PF14835.6 ORY16530.1 - 0.00025 20.8 0.9 0.00033 20.5 0.9 1.3 1 0 0 1 1 1 1 zf-RING of BARD1-type protein RINGv PF12906.7 ORY16530.1 - 0.00031 20.8 3.4 0.00089 19.3 3.4 1.8 1 1 0 1 1 1 1 RING-variant domain zf-ANAPC11 PF12861.7 ORY16530.1 - 0.00058 19.9 2.1 0.00071 19.6 2.1 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3H2C3 PF17122.5 ORY16530.1 - 0.02 14.9 2.5 0.074 13.1 2.5 1.9 1 1 0 1 1 1 0 Zinc-finger zf-RING-like PF08746.11 ORY16530.1 - 0.048 14.0 2.6 0.083 13.2 2.6 1.5 1 1 0 1 1 1 0 RING-like domain YdjO PF14169.6 ORY16530.1 - 0.056 13.2 0.0 2.8 7.7 0.0 2.2 2 0 0 2 2 2 0 Cold-inducible protein YdjO Zf_RING PF16744.5 ORY16530.1 - 0.076 13.1 0.5 0.076 13.1 0.5 1.5 1 1 0 1 1 1 0 KIAA1045 RING finger FANCL_C PF11793.8 ORY16530.1 - 0.076 13.2 8.0 1.8 8.8 8.0 2.5 1 1 0 1 1 1 0 FANCL C-terminal domain PHD PF00628.29 ORY16530.1 - 0.94 9.4 6.0 3.8 7.5 6.1 1.9 1 1 1 2 2 2 0 PHD-finger DUF778 PF05608.12 ORY16532.1 - 0.22 11.9 4.3 0.27 11.6 4.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF778) HLH PF00010.26 ORY16533.1 - 3.1e-13 49.5 0.1 5.6e-13 48.6 0.1 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain bZIP_2 PF07716.15 ORY16533.1 - 0.11 12.5 6.1 0.055 13.6 1.4 2.3 2 0 0 2 2 2 0 Basic region leucine zipper HSP20 PF00011.21 ORY16535.1 - 6.5e-08 32.7 3.9 1e-07 32.0 0.0 2.8 3 0 0 3 3 3 1 Hsp20/alpha crystallin family ETRAMP PF09716.10 ORY16535.1 - 0.003 17.6 0.5 0.0037 17.3 0.5 1.2 1 0 0 1 1 1 1 Malarial early transcribed membrane protein (ETRAMP) LIM_bind PF01803.16 ORY16535.1 - 0.017 14.7 1.5 4.1 6.9 0.0 2.2 2 0 0 2 2 2 0 LIM-domain binding protein SR-25 PF10500.9 ORY16535.1 - 0.29 10.7 22.1 0.77 9.3 22.1 1.7 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Presenilin PF01080.17 ORY16535.1 - 1.3 7.7 3.3 2 7.1 3.3 1.2 1 0 0 1 1 1 0 Presenilin MRP-S27 PF10037.9 ORY16535.1 - 1.3 7.8 9.7 1.8 7.3 9.7 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 Med19 PF10278.9 ORY16535.1 - 1.6 8.6 19.6 4.1 7.3 19.6 1.6 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Protocadherin PF08374.11 ORY16535.1 - 2.4 8.1 10.4 4.7 7.1 10.4 1.4 1 0 0 1 1 1 0 Protocadherin Ferlin_C PF16165.5 ORY16535.1 - 4.7 7.1 14.3 8.5 6.3 14.3 1.4 1 0 0 1 1 1 0 Ferlin C-terminus Peptidase_S49_N PF08496.10 ORY16535.1 - 5.8 7.0 15.5 9.1 6.3 15.5 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal APH PF01636.23 ORY16536.1 - 0.027 14.4 0.0 0.11 12.4 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF3328 PF11807.8 ORY16538.1 - 1.8e-09 37.7 0.0 2.4e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF2237 PF09996.9 ORY16539.1 - 4.6e-40 136.2 0.0 5.8e-40 135.9 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2237) ELL PF10390.9 ORY16540.1 - 0.19 11.2 0.0 0.19 11.2 0.0 2.6 2 1 0 2 2 2 0 RNA polymerase II elongation factor ELL Tmemb_cc2 PF10267.9 ORY16540.1 - 5.5 6.0 5.9 0.58 9.2 0.4 2.0 2 0 0 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein UQ_con PF00179.26 ORY16542.1 - 1.6e-46 157.5 0.0 1.8e-46 157.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 ORY16542.1 - 0.038 14.3 0.0 0.043 14.1 0.0 1.3 1 0 0 1 1 1 0 RWD domain UEV PF05743.13 ORY16542.1 - 0.064 13.1 0.0 0.088 12.7 0.0 1.3 1 0 0 1 1 1 0 UEV domain DUF155 PF02582.14 ORY16543.1 - 5.1e-57 192.8 1.3 5.9e-57 192.6 0.1 1.8 2 1 0 2 2 2 1 Uncharacterised ACR, YagE family COG1723 TsaE PF02367.17 ORY16543.1 - 0.059 13.4 0.1 0.15 12.1 0.1 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RGS PF00615.19 ORY16544.1 - 2.3e-13 50.5 0.0 3.8e-10 40.1 0.0 2.3 2 0 0 2 2 2 2 Regulator of G protein signaling domain 2OG-FeII_Oxy_3 PF13640.6 ORY16545.1 - 6.1e-09 36.7 0.0 1.4e-08 35.5 0.0 1.6 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily NOG1_N PF17835.1 ORY16546.1 - 0.15 12.0 0.0 8 6.4 0.0 2.3 2 0 0 2 2 2 0 NOG1 N-terminal helical domain HSP70 PF00012.20 ORY16547.1 - 2.8e-06 25.8 0.0 5.8e-06 24.8 0.0 1.4 1 0 0 1 1 1 1 Hsp70 protein Glyco_tran_WbsX PF14307.6 ORY16547.1 - 0.13 11.7 0.1 0.25 10.8 0.1 1.4 1 0 0 1 1 1 0 Glycosyltransferase WbsX Sugar_tr PF00083.24 ORY16552.1 - 6.7e-77 259.3 23.9 7.7e-77 259.1 23.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY16552.1 - 9.9e-14 51.0 36.6 1.6e-13 50.3 34.2 2.2 1 1 2 3 3 3 3 Major Facilitator Superfamily DUF366 PF04017.12 ORY16554.1 - 0.11 11.9 0.1 0.23 10.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF366) PP2C PF00481.21 ORY16555.1 - 6.6e-36 124.3 0.0 9.6e-36 123.7 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 ORY16555.1 - 0.14 12.0 0.0 74 3.2 0.0 3.5 4 0 0 4 4 4 0 Stage II sporulation protein E (SpoIIE) CLTH PF10607.9 ORY16556.1 - 8.7e-33 113.3 0.3 1.4e-32 112.6 0.3 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.28 ORY16556.1 - 5.7e-24 84.5 0.2 1.3e-23 83.4 0.2 1.6 1 0 0 1 1 1 1 SPRY domain LisH PF08513.11 ORY16556.1 - 0.00088 19.2 0.1 0.0022 17.9 0.1 1.7 1 0 0 1 1 1 1 LisH DUF3971 PF13116.6 ORY16556.1 - 0.08 12.5 0.1 0.52 9.8 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function INO80_Ies4 PF08193.11 ORY16557.1 - 3.2e-63 213.9 18.2 4.2e-63 213.6 18.2 1.1 1 0 0 1 1 1 1 INO80 complex subunit Ies4 BrnA_antitoxin PF14384.6 ORY16557.1 - 0.0049 17.3 0.1 0.024 15.1 0.0 2.2 2 0 0 2 2 2 1 BrnA antitoxin of type II toxin-antitoxin system DUF4332 PF14229.6 ORY16561.1 - 0.047 13.9 0.2 0.14 12.4 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4332) CAP59_mtransfer PF11735.8 ORY16562.1 - 3.4e-81 272.5 0.0 4.3e-81 272.2 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Septum_form PF13845.6 ORY16563.1 - 0.019 14.5 0.0 0.052 13.1 0.0 1.6 2 0 0 2 2 2 0 Septum formation Tmemb_170 PF10190.9 ORY16565.1 - 0.098 13.0 5.7 0.052 13.9 4.0 1.5 1 1 0 1 1 1 0 Putative transmembrane protein 170 Glyco_transf_90 PF05686.12 ORY16566.1 - 2e-12 46.7 0.1 4.9e-12 45.5 0.1 1.6 1 1 0 1 1 1 1 Glycosyl transferase family 90 Ank_2 PF12796.7 ORY16567.1 - 1.7e-15 57.4 0.0 4.3e-08 33.6 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY16567.1 - 4.1e-10 40.0 0.2 7.5e-05 23.2 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 ORY16567.1 - 1.3e-09 38.1 0.0 7e-05 23.0 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 ORY16567.1 - 3.2e-08 33.6 0.3 0.035 14.6 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 ORY16567.1 - 1.2e-06 28.4 0.2 0.043 14.4 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Glyco_hydro_16 PF00722.21 ORY16570.1 - 5.8e-41 139.9 3.0 9e-41 139.3 3.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Ribosomal_S5_C PF03719.15 ORY16570.1 - 0.037 13.5 0.1 4.7 6.8 0.0 2.5 2 0 0 2 2 2 0 Ribosomal protein S5, C-terminal domain TMEM108 PF15759.5 ORY16570.1 - 0.076 12.0 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 TMEM108 family UvrA_DNA-bind PF17755.1 ORY16570.1 - 0.12 12.7 0.1 0.32 11.4 0.1 1.7 1 0 0 1 1 1 0 UvrA DNA-binding domain TFB6 PF17110.5 ORY16571.1 - 6e-62 208.4 0.0 7.3e-62 208.1 0.0 1.1 1 0 0 1 1 1 1 Subunit 11 of the general transcription factor TFIIH Acetyltransf_1 PF00583.25 ORY16574.1 - 4.1e-09 36.7 0.0 6.2e-08 32.9 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ORY16574.1 - 2.3e-08 34.3 0.0 3e-07 30.7 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ORY16574.1 - 3.8e-08 33.2 0.0 6.9e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 ORY16574.1 - 5.5e-08 32.8 0.0 1.5e-07 31.4 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 ORY16574.1 - 0.035 14.8 0.0 0.078 13.6 0.0 1.6 1 1 1 2 2 2 0 Acetyltransferase (GNAT) domain Sugar_tr PF00083.24 ORY16575.1 - 1.6e-80 271.2 25.7 1.8e-80 271.0 25.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY16575.1 - 5.6e-28 97.9 34.5 1.2e-21 77.0 13.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily NapE PF06796.11 ORY16575.1 - 0.12 11.9 1.8 0.56 9.8 1.3 2.4 2 0 0 2 2 2 0 Periplasmic nitrate reductase protein NapE P-mevalo_kinase PF04275.14 ORY16576.1 - 1.7e-21 76.2 0.0 3.3e-21 75.4 0.0 1.5 1 0 0 1 1 1 1 Phosphomevalonate kinase Pribosyltran PF00156.27 ORY16576.1 - 3.6e-20 72.1 0.0 6.5e-20 71.3 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain FAD_binding_4 PF01565.23 ORY16576.1 - 4.2e-15 55.7 4.5 2e-14 53.5 3.3 2.4 2 0 0 2 2 2 1 FAD binding domain UPRTase PF14681.6 ORY16576.1 - 0.0009 18.7 0.1 0.0018 17.7 0.1 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.6 ORY16576.1 - 0.0021 17.6 0.7 0.017 14.6 0.0 2.5 3 0 0 3 3 3 1 Phosphoribosyl transferase BBE PF08031.12 ORY16576.1 - 0.0041 17.2 0.0 0.0092 16.1 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like Methyltransf_23 PF13489.6 ORY16576.1 - 0.015 15.1 0.0 0.039 13.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain AflR PF08493.10 ORY16577.1 - 1.2e-11 44.7 0.4 1.9e-11 44.0 0.4 1.3 1 0 0 1 1 1 1 Aflatoxin regulatory protein Zn_clus PF00172.18 ORY16577.1 - 9e-09 35.3 6.8 2.2e-08 34.1 6.8 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mei5 PF10376.9 ORY16580.1 - 0.55 10.1 5.1 3.5 7.4 0.1 2.5 3 0 0 3 3 3 0 Double-strand recombination repair protein DUF4419 PF14388.6 ORY16581.1 - 1.9e-97 326.3 0.0 2.4e-97 326.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) GWT1 PF06423.12 ORY16582.1 - 1.4e-41 142.0 1.9 1.4e-41 142.0 1.9 2.0 2 0 0 2 2 2 1 GWT1 DUF4818 PF16089.5 ORY16582.1 - 0.0023 18.4 3.0 0.0057 17.1 0.0 3.0 3 1 0 3 3 3 1 Domain of unknown function (DUF4818) DUF4896 PF16237.5 ORY16582.1 - 0.048 13.5 4.3 0.55 10.1 1.6 3.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4896) zf-Tim10_DDP PF02953.15 ORY16584.1 - 7.6e-21 73.5 1.6 9.2e-21 73.3 1.6 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger adh_short PF00106.25 ORY16585.1 - 2.7e-46 157.5 0.1 3.4e-46 157.2 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY16585.1 - 1.1e-32 113.4 0.0 1.4e-32 113.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY16585.1 - 2.3e-07 30.9 0.0 3.6e-07 30.3 0.0 1.3 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 ORY16585.1 - 0.00049 20.0 0.0 0.00093 19.1 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding THF_DHG_CYH_C PF02882.19 ORY16585.1 - 0.0029 17.0 0.0 0.0062 15.9 0.0 1.6 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Shikimate_DH PF01488.20 ORY16585.1 - 0.0066 16.5 0.0 0.011 15.9 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.21 ORY16585.1 - 0.025 14.0 0.1 0.063 12.7 0.0 1.7 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family F-box PF00646.33 ORY16586.1 - 0.0013 18.6 0.2 0.0061 16.4 0.0 2.3 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 ORY16586.1 - 0.0041 17.0 0.9 0.013 15.4 0.0 2.3 2 0 0 2 2 2 1 F-box-like F-box_4 PF15966.5 ORY16586.1 - 0.0083 16.0 0.0 0.02 14.8 0.0 1.7 1 0 0 1 1 1 1 F-box GRDP-like PF07173.12 ORY16588.1 - 7.5e-25 88.2 0.9 5.5e-20 72.5 0.1 2.4 2 0 0 2 2 2 2 Glycine-rich domain-containing protein-like DUF3077 PF11275.8 ORY16588.1 - 0.14 12.4 0.0 0.32 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3077) Lipase_3 PF01764.25 ORY16589.1 - 2.1e-15 56.8 0.0 6.5e-15 55.2 0.0 1.8 2 0 0 2 2 2 1 Lipase (class 3) Ank_2 PF12796.7 ORY16591.1 - 8.1e-23 80.8 0.0 2e-12 47.5 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY16591.1 - 8.8e-17 61.3 0.1 2.3e-06 28.0 0.0 3.1 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 ORY16591.1 - 2.6e-13 49.7 0.3 0.00013 22.2 0.1 3.9 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 ORY16591.1 - 7.8e-13 47.4 0.0 0.00027 21.1 0.0 3.9 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 ORY16591.1 - 8.4e-12 45.1 0.0 4.8e-05 23.6 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) TolA PF06519.11 ORY16591.1 - 0.017 15.3 0.0 0.96 9.7 0.0 2.1 2 0 0 2 2 2 0 TolA C-terminal Pkinase PF00069.25 ORY16592.1 - 3.5e-29 102.0 0.0 5.6e-29 101.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY16592.1 - 2.5e-19 69.6 0.0 1.2e-18 67.4 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Tcell_CD4_C PF12104.8 ORY16592.1 - 0.021 14.8 2.0 0.038 13.9 2.0 1.4 1 0 0 1 1 1 0 T cell CD4 receptor C terminal region ATG2_CAD PF13329.6 ORY16593.1 - 5.1e-41 140.0 0.0 1.5e-40 138.5 0.0 1.9 1 0 0 1 1 1 1 Autophagy-related protein 2 CAD motif ATG_C PF09333.11 ORY16593.1 - 1.8e-28 98.7 0.8 1.7e-27 95.6 0.1 2.8 3 0 0 3 3 3 1 Autophagy-related protein C terminal domain A_deaminase PF00962.22 ORY16594.1 - 2.8e-23 82.8 0.0 4.2e-23 82.2 0.0 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase Fib_alpha PF08702.10 ORY16596.1 - 0.00035 20.8 12.6 0.0017 18.5 2.3 3.2 2 1 1 3 3 3 1 Fibrinogen alpha/beta chain family Tropomyosin PF00261.20 ORY16596.1 - 0.0065 15.9 4.3 0.0065 15.9 4.3 2.7 2 1 0 3 3 3 1 Tropomyosin GAS PF13851.6 ORY16596.1 - 0.027 13.8 22.8 0.021 14.1 14.0 2.6 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding Goodbye PF17109.5 ORY16596.1 - 0.032 14.7 5.5 1.4 9.4 0.9 2.6 2 0 0 2 2 2 0 fungal STAND N-terminal Goodbye domain DUF4618 PF15397.6 ORY16596.1 - 0.35 10.2 19.2 3.6 6.9 18.8 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) SlyX PF04102.12 ORY16596.1 - 0.4 11.3 22.9 1.4 9.6 6.7 4.5 3 1 0 3 3 3 0 SlyX DUF724 PF05266.14 ORY16596.1 - 0.57 10.0 11.0 1.4 8.7 11.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF724) MAD PF05557.13 ORY16596.1 - 1.1 7.5 25.7 0.13 10.7 20.7 1.7 2 0 0 2 2 2 0 Mitotic checkpoint protein Prefoldin PF02996.17 ORY16596.1 - 1.1 9.1 12.2 1.2 9.1 1.6 3.6 3 1 0 3 3 3 0 Prefoldin subunit Fez1 PF06818.15 ORY16596.1 - 1.2 9.6 23.3 0.51 10.8 16.9 2.3 1 1 0 2 2 2 0 Fez1 LemA PF04011.12 ORY16596.1 - 1.2 8.9 5.5 0.94 9.3 0.1 2.5 2 0 0 2 2 2 0 LemA family RPW8 PF05659.11 ORY16596.1 - 1.8 8.3 6.9 4.2 7.1 0.9 2.9 3 0 0 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 LMBR1 PF04791.16 ORY16596.1 - 2.4 7.0 4.9 3.9 6.3 4.9 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF948 PF06103.11 ORY16596.1 - 4.7 7.5 9.7 36 4.7 0.2 3.2 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Tropomyosin_1 PF12718.7 ORY16596.1 - 6.2 7.0 27.2 7.5 6.7 0.1 3.1 2 1 0 2 2 2 0 Tropomyosin like FapA PF03961.13 ORY16596.1 - 7.6 5.0 11.8 3.9 6.0 8.2 2.0 1 1 0 2 2 2 0 Flagellar Assembly Protein A ABC_tran_CTD PF16326.5 ORY16596.1 - 8.9 6.6 29.8 4.4 7.6 3.8 4.1 1 1 3 4 4 4 0 ABC transporter C-terminal domain FUSC PF04632.12 ORY16596.1 - 8.9 4.7 25.8 3.3 6.1 9.1 2.1 1 1 1 2 2 2 0 Fusaric acid resistance protein family TPR_MLP1_2 PF07926.12 ORY16596.1 - 9.1 6.4 31.3 0.41 10.7 6.0 3.5 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein Clr2_transil PF16761.5 ORY16597.1 - 8.6e-20 71.3 0.3 1.9e-19 70.2 0.3 1.6 1 0 0 1 1 1 1 Transcription-silencing protein, cryptic loci regulator Clr2 Clr2 PF10383.9 ORY16597.1 - 6.4e-09 36.7 0.0 1.2e-08 35.9 0.0 1.4 1 0 0 1 1 1 1 Transcription-silencing protein Clr2 PPP4R2 PF09184.11 ORY16602.1 - 7.2e-10 38.9 13.4 2.5e-08 33.9 4.0 2.6 2 1 0 2 2 2 2 PPP4R2 GWT1 PF06423.12 ORY16603.1 - 4.5 7.4 8.9 10 6.2 0.5 2.9 1 1 1 2 2 2 0 GWT1 Mpv17_PMP22 PF04117.12 ORY16604.1 - 4.9e-21 74.7 0.7 8e-21 74.0 0.7 1.3 1 0 0 1 1 1 1 Mpv17 / PMP22 family Pkinase PF00069.25 ORY16605.1 - 2.6e-65 220.4 0.0 3.7e-65 219.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY16605.1 - 6.5e-37 127.2 0.0 3.9e-31 108.3 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 ORY16605.1 - 6.7e-07 28.9 0.0 0.0012 18.2 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 ORY16605.1 - 0.004 17.1 0.0 0.0079 16.1 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 ORY16605.1 - 0.019 14.6 0.0 0.034 13.7 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Haspin_kinase PF12330.8 ORY16605.1 - 0.026 13.5 0.2 0.041 12.8 0.2 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 ORY16605.1 - 0.22 10.9 0.1 0.39 10.0 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 ORY16605.1 - 3.1 6.5 4.9 0.78 8.4 0.1 2.2 2 0 0 2 2 2 0 Fungal protein kinase Pyr_redox_2 PF07992.14 ORY16606.1 - 7.2e-52 176.4 2.9 9.4e-52 176.1 2.9 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.26 ORY16606.1 - 5.3e-15 55.1 0.0 1.4e-14 53.8 0.0 1.7 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox PF00070.27 ORY16606.1 - 8.3e-15 55.1 0.6 8.3e-15 55.1 0.6 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Reductase_C PF14759.6 ORY16606.1 - 1.5e-07 31.8 0.0 4.2e-07 30.4 0.0 1.8 2 0 0 2 2 2 1 Reductase C-terminal Rieske_2 PF13806.6 ORY16606.1 - 3.8e-05 23.5 0.0 0.00021 21.2 0.0 2.3 3 0 0 3 3 3 1 Rieske-like [2Fe-2S] domain PRMT5 PF05185.16 ORY16606.1 - 0.015 15.2 0.0 0.031 14.1 0.0 1.4 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Trp_halogenase PF04820.14 ORY16606.1 - 0.17 10.7 0.1 0.17 10.7 0.1 1.5 2 0 0 2 2 2 0 Tryptophan halogenase HI0933_like PF03486.14 ORY16606.1 - 0.56 8.9 3.1 11 4.5 0.0 2.6 3 0 0 3 3 3 0 HI0933-like protein Glyco_hydro_31 PF01055.26 ORY16610.1 - 1.8e-155 518.5 2.2 2.3e-155 518.1 2.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 ORY16610.1 - 1.6e-31 108.9 0.0 2.6e-31 108.2 0.0 1.3 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 ORY16610.1 - 7e-05 23.1 1.0 0.00024 21.4 0.1 2.5 2 0 0 2 2 2 1 Galactose mutarotase-like DUF846 PF05832.12 ORY16611.1 - 0.078 13.0 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF846) DUF899 PF05988.12 ORY16612.1 - 6.2e-44 150.1 0.0 9e-44 149.6 0.0 1.2 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF899) MFS_1 PF07690.16 ORY16613.1 - 1.2e-38 132.9 30.6 1.2e-38 132.9 30.6 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1772 PF08592.11 ORY16613.1 - 6.1e-05 23.4 0.0 6.1e-05 23.4 0.0 3.7 3 2 0 3 3 3 1 Domain of unknown function (DUF1772) BTB PF00651.31 ORY16614.1 - 0.015 15.5 0.0 0.079 13.2 0.0 2.0 1 1 0 1 1 1 0 BTB/POZ domain ARL2_Bind_BART PF11527.8 ORY16615.1 - 0.062 13.4 0.0 0.076 13.1 0.0 1.1 1 0 0 1 1 1 0 The ARF-like 2 binding protein BART DAO PF01266.24 ORY16616.1 - 6.2e-33 114.8 0.0 7.1e-33 114.6 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Glu_dehyd_C PF16912.5 ORY16616.1 - 0.048 13.1 0.0 0.083 12.4 0.0 1.3 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus NAD_binding_8 PF13450.6 ORY16616.1 - 0.12 12.6 0.0 0.24 11.7 0.0 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HeLo PF14479.6 ORY16619.1 - 2e-19 70.3 0.0 3.1e-19 69.6 0.0 1.3 1 0 0 1 1 1 1 Prion-inhibition and propagation WD40 PF00400.32 ORY16621.1 - 1.1e-12 48.2 9.4 0.00068 20.4 0.1 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY16621.1 - 1.3e-07 31.8 2.7 0.01 16.1 0.0 4.4 3 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain RNA_pol_Rpb1_1 PF04997.12 ORY16622.1 - 1.3e-105 353.1 0.0 4e-105 351.6 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 ORY16622.1 - 3.7e-101 338.0 0.1 5.1e-101 337.6 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 ORY16622.1 - 1e-75 253.6 0.1 1.7e-75 252.8 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 ORY16622.1 - 1.4e-63 214.2 0.5 2.9e-63 213.2 0.5 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.18 ORY16622.1 - 1.7e-47 161.3 0.0 3.2e-47 160.4 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.12 ORY16622.1 - 1.9e-42 144.4 7.6 3.8e-42 143.5 7.6 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.17 ORY16622.1 - 3.3e-34 117.1 0.0 9.1e-34 115.7 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.13 ORY16622.1 - 2.7e-13 49.5 238.2 0.0015 18.8 11.5 15.4 11 3 5 17 17 17 13 RNA polymerase Rpb1 C-terminal repeat Bromodomain PF00439.25 ORY16623.1 - 5.9e-23 80.7 1.0 1.1e-22 79.8 1.0 1.5 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 ORY16623.1 - 3.8e-08 33.6 0.0 6.8e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ORY16623.1 - 4.3e-07 29.9 0.2 9e-07 28.9 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ORY16623.1 - 0.00032 21.0 0.1 0.00065 20.1 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ORY16623.1 - 0.14 12.1 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein Ost5 PF05251.12 ORY16624.1 - 3.5e-21 75.2 8.2 4e-21 75.0 8.2 1.1 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit 5 Rad1 PF02144.16 ORY16625.1 - 1.8e-85 286.4 0.0 2e-85 286.2 0.0 1.0 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 TFIIA PF03153.13 ORY16626.1 - 2.5e-80 271.5 43.0 7.4e-80 270.0 43.0 1.6 1 1 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DDHD PF02862.17 ORY16626.1 - 6.8e-05 23.1 3.6 8.3e-05 22.9 3.6 1.3 1 0 0 1 1 1 1 DDHD domain PPL5 PF18168.1 ORY16626.1 - 0.049 12.9 7.9 0.092 12.0 7.9 1.4 1 0 0 1 1 1 0 Prim-pol family 5 SpoIIP PF07454.11 ORY16626.1 - 0.052 13.0 9.2 0.09 12.2 9.2 1.4 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Band_3_cyto PF07565.13 ORY16626.1 - 0.061 13.1 9.3 0.085 12.6 9.3 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain MDM10 PF12519.8 ORY16626.1 - 0.078 11.8 3.3 0.089 11.7 3.3 1.2 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 GREB1 PF15782.5 ORY16626.1 - 0.34 8.0 10.7 0.47 7.5 10.7 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Presenilin PF01080.17 ORY16626.1 - 0.5 9.1 15.8 0.69 8.6 15.8 1.2 1 0 0 1 1 1 0 Presenilin Peptidase_S49_N PF08496.10 ORY16626.1 - 0.72 9.9 10.1 1.4 9.0 10.1 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal MMR1 PF08505.10 ORY16626.1 - 0.73 10.1 19.0 0.12 12.7 14.9 1.7 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein eIF-3_zeta PF05091.12 ORY16626.1 - 0.82 8.6 21.2 1.2 8.0 21.2 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) YL1 PF05764.13 ORY16626.1 - 0.86 9.7 21.3 0.33 11.0 9.7 2.3 2 0 0 2 2 2 0 YL1 nuclear protein TERB2 PF15101.6 ORY16626.1 - 1.2 9.2 18.4 3.1 7.8 18.4 1.8 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Sec62 PF03839.16 ORY16626.1 - 1.2 8.6 6.6 2.1 7.8 6.6 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 Zip PF02535.22 ORY16626.1 - 1.5 8.0 5.3 1.9 7.7 5.3 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter EOS1 PF12326.8 ORY16626.1 - 1.5 8.7 4.8 2.4 8.0 4.8 1.3 1 0 0 1 1 1 0 N-glycosylation protein RR_TM4-6 PF06459.12 ORY16626.1 - 1.8 8.3 15.5 0.33 10.8 11.3 1.8 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 EMC3_TMCO1 PF01956.16 ORY16626.1 - 2.3 7.9 8.6 3.6 7.3 8.6 1.5 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like NARP1 PF12569.8 ORY16626.1 - 2.8 6.7 15.0 4.4 6.1 15.0 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Vac7 PF12751.7 ORY16626.1 - 3.3 7.0 10.7 4.8 6.5 10.7 1.2 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 FYDLN_acid PF09538.10 ORY16626.1 - 4.2 8.1 18.0 6.6 7.5 5.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Ctr PF04145.15 ORY16626.1 - 5.3 7.7 6.7 4.3 7.9 5.1 1.8 2 0 0 2 2 1 0 Ctr copper transporter family CPSF100_C PF13299.6 ORY16626.1 - 5.7 7.1 11.1 3.7 7.7 9.0 1.8 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal SLC12 PF03522.15 ORY16626.1 - 6 5.8 16.1 9 5.2 16.1 1.2 1 0 0 1 1 1 0 Solute carrier family 12 DUF1980 PF09323.10 ORY16626.1 - 7.1 6.5 10.9 21 5.0 10.9 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Hydin_ADK PF17213.3 ORY16626.1 - 7.3 6.8 12.8 15 5.8 12.8 1.5 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Connexin PF00029.19 ORY16626.1 - 7.4 6.3 9.9 11 5.7 9.9 1.2 1 0 0 1 1 1 0 Connexin Pex14_N PF04695.13 ORY16626.1 - 7.5 7.2 36.9 0.66 10.6 24.4 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Plasmodium_Vir PF05795.11 ORY16626.1 - 8.7 5.7 8.5 15 4.8 8.5 1.4 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF4407 PF14362.6 ORY16626.1 - 8.9 5.6 21.7 14 5.0 21.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Hid1 PF12722.7 ORY16626.1 - 9 4.3 14.5 13 3.8 14.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Baculo_PP31 PF05311.11 ORY16626.1 - 9.8 5.6 12.2 18 4.7 12.2 1.4 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) bZIP_1 PF00170.21 ORY16627.1 - 0.0097 16.0 3.5 0.0097 16.0 3.5 2.1 2 0 0 2 2 2 1 bZIP transcription factor Synaptonemal_3 PF15191.6 ORY16627.1 - 0.022 14.5 0.2 0.042 13.6 0.2 1.4 1 0 0 1 1 1 0 Synaptonemal complex central element protein 3 FlaC_arch PF05377.11 ORY16627.1 - 0.22 12.0 0.7 0.53 10.7 0.7 1.6 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) Glutaredoxin2_C PF04399.13 ORY16627.1 - 0.24 11.2 0.7 0.47 10.3 0.3 1.7 2 0 0 2 2 2 0 Glutaredoxin 2, C terminal domain PAF-AH_p_II PF03403.13 ORY16628.1 - 3.2e-53 180.6 0.0 1.3e-29 102.9 0.0 3.1 3 0 0 3 3 3 3 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 ORY16628.1 - 1.3e-05 24.2 0.0 0.0005 19.1 0.0 2.1 2 0 0 2 2 2 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 ORY16628.1 - 0.00056 19.3 0.0 0.65 9.2 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Chlorophyllase PF07224.11 ORY16628.1 - 0.039 13.0 0.0 0.079 12.0 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase ThiF PF00899.21 ORY16629.1 - 4.9e-58 196.4 0.0 7.5e-58 195.8 0.0 1.2 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.20 ORY16629.1 - 6e-07 30.0 0.0 2e-06 28.2 0.0 1.9 2 0 0 2 2 2 1 Rhodanese-like domain Spc24 PF08286.11 ORY16629.1 - 0.032 14.5 0.2 0.062 13.5 0.2 1.4 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 NAD_binding_7 PF13241.6 ORY16629.1 - 0.036 14.5 0.0 0.071 13.6 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding She9_MDM33 PF05546.11 ORY16629.1 - 0.052 13.4 0.3 0.072 12.9 0.3 1.2 1 0 0 1 1 1 0 She9 / Mdm33 family CdvA PF18822.1 ORY16629.1 - 0.057 13.2 0.6 0.11 12.4 0.6 1.3 1 0 0 1 1 1 0 CdvA-like coiled-coil domain FlxA PF14282.6 ORY16629.1 - 0.08 12.9 6.3 0.15 12.1 6.3 1.3 1 0 0 1 1 1 0 FlxA-like protein DUF3584 PF12128.8 ORY16629.1 - 0.083 10.4 0.4 0.11 10.0 0.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Prefoldin_2 PF01920.20 ORY16629.1 - 0.13 12.2 2.9 0.22 11.5 2.9 1.3 1 0 0 1 1 1 0 Prefoldin subunit HET PF06985.11 ORY16630.1 - 3.1e-23 82.7 0.0 5.5e-23 81.9 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SLX9 PF15341.6 ORY16632.1 - 1.3e-34 119.4 6.7 1.3e-34 119.4 6.7 1.5 2 0 0 2 2 2 1 Ribosome biogenesis protein SLX9 Peptidase_A2E PF12382.8 ORY16632.1 - 0.013 15.5 0.0 0.018 15.1 0.0 1.2 1 0 0 1 1 1 0 Retrotransposon peptidase AA_permease_2 PF13520.6 ORY16633.1 - 2.6e-56 191.3 52.5 3.3e-56 190.9 52.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ORY16633.1 - 7.5e-28 97.3 43.7 9.9e-28 96.9 43.7 1.1 1 0 0 1 1 1 1 Amino acid permease AtuA PF07287.11 ORY16636.1 - 8.6e-123 409.5 0.1 1e-122 409.2 0.1 1.1 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA CoA_transf_3 PF02515.17 ORY16637.1 - 2.3e-35 122.4 0.0 4.5e-33 114.9 0.0 2.2 2 0 0 2 2 2 2 CoA-transferase family III Collagen PF01391.18 ORY16637.1 - 0.013 15.3 11.5 0.026 14.3 11.5 1.4 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) Acetyltransf_3 PF13302.7 ORY16638.1 - 8.4e-17 62.1 0.0 1.5e-16 61.4 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain RadC PF04002.15 ORY16638.1 - 0.23 11.4 0.0 0.33 10.9 0.0 1.2 1 0 0 1 1 1 0 RadC-like JAB domain Glyoxalase PF00903.25 ORY16639.1 - 4.1e-08 33.5 1.8 2.3e-05 24.6 0.8 2.8 2 2 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DUF3328 PF11807.8 ORY16640.1 - 1.2e-09 38.3 0.0 1.4e-09 38.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) p450 PF00067.22 ORY16641.1 - 1.2e-38 133.0 0.0 2.1e-37 129.0 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 DpnII PF04556.12 ORY16641.1 - 0.057 12.7 0.0 1.2 8.4 0.0 2.1 2 0 0 2 2 2 0 DpnII restriction endonuclease DUF5023 PF16426.5 ORY16641.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5023) S1-P1_nuclease PF02265.16 ORY16643.1 - 6.7e-57 193.2 0.0 7.6e-57 193.0 0.0 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease Nucleos_tra2_C PF07662.13 ORY16644.1 - 5.4e-69 232.2 0.2 5.4e-69 232.2 0.2 2.3 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 ORY16644.1 - 1.4e-23 83.3 7.1 1.5e-23 83.1 4.3 2.7 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter N-terminus SSF PF00474.17 ORY16645.1 - 1.3e-20 73.7 32.9 1.9e-20 73.1 32.9 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family Thioredoxin_16 PF18569.1 ORY16647.1 - 0.4 10.8 0.1 0.4 10.8 0.1 2.3 3 0 0 3 3 3 0 Thioredoxin-like domain HET PF06985.11 ORY16648.1 - 5.2e-24 85.3 0.0 7.8e-24 84.7 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Sporozoite_P67 PF05642.11 ORY16650.1 - 0.038 12.1 3.3 0.057 11.5 3.3 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Methyltransf_23 PF13489.6 ORY16652.1 - 3.5e-18 66.0 0.0 4.6e-18 65.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY16652.1 - 4.4e-08 33.7 0.0 1.1e-07 32.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY16652.1 - 7.9e-06 26.4 0.0 1.4e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY16652.1 - 0.00023 21.0 0.0 0.0016 18.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY16652.1 - 0.00035 21.3 0.0 0.0019 18.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ORY16652.1 - 0.0083 15.7 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 ORY16652.1 - 0.051 13.0 0.0 0.089 12.3 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase SBF PF01758.16 ORY16654.1 - 1.3e-52 178.4 7.6 1.3e-52 178.4 7.6 2.3 3 0 0 3 3 3 1 Sodium Bile acid symporter family Kinocilin PF15033.6 ORY16654.1 - 0.018 14.7 3.1 0.44 10.2 0.7 2.7 2 0 0 2 2 2 0 Kinocilin protein PIG-P PF08510.12 ORY16654.1 - 3.6 7.5 5.5 15 5.6 0.1 3.3 2 1 1 3 3 3 0 PIG-P DUF2897 PF11446.8 ORY16654.1 - 5.8 6.9 6.5 14 5.6 6.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) zf-C3HC4_2 PF13923.6 ORY16690.1 - 6.6e-10 38.7 12.3 9.3e-10 38.2 12.3 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORY16690.1 - 1.3e-08 34.7 9.3 3.3e-08 33.4 9.4 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 ORY16690.1 - 7.8e-08 32.1 13.9 1.1e-07 31.6 13.9 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORY16690.1 - 8.1e-08 32.1 13.9 1.1e-07 31.7 13.9 1.2 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 ORY16690.1 - 5.6e-07 29.3 11.9 7.7e-07 28.9 11.9 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 ORY16690.1 - 5.6e-06 26.4 10.1 1.2e-05 25.4 10.2 1.5 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 ORY16690.1 - 7.2e-06 25.8 5.5 1e-05 25.3 5.5 1.2 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_2 PF13639.6 ORY16690.1 - 7.4e-06 26.2 13.7 1.1e-05 25.6 13.7 1.3 1 0 0 1 1 1 1 Ring finger domain U-box PF04564.15 ORY16690.1 - 4.1e-05 23.7 0.0 6.2e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 U-box domain Prok-RING_4 PF14447.6 ORY16690.1 - 8.4e-05 22.4 11.0 0.00013 21.7 11.0 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 ORY16690.1 - 0.0025 18.1 10.4 0.0075 16.5 10.4 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_10 PF16685.5 ORY16690.1 - 0.0056 16.8 8.3 0.0088 16.2 8.3 1.3 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-RING_4 PF14570.6 ORY16690.1 - 0.013 15.3 9.7 0.019 14.8 6.2 2.1 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Mob_synth_C PF06463.13 ORY16690.1 - 0.023 14.6 9.3 0.03 14.3 9.0 1.4 1 1 0 1 1 1 0 Molybdenum Cofactor Synthesis C zf-ANAPC11 PF12861.7 ORY16690.1 - 0.091 12.8 6.3 0.2 11.7 6.3 1.5 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-P11 PF03854.14 ORY16690.1 - 0.16 11.7 8.7 1.1 9.0 8.9 1.9 1 1 0 1 1 1 0 P-11 zinc finger Glyco_hydro_11 PF00457.17 ORY16691.1 - 1.6e-81 272.2 22.2 1.9e-81 271.9 22.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 ESSS PF10183.9 ORY16692.1 - 1.7e-15 57.1 0.0 1.8e-15 57.0 0.0 1.1 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Snf7 PF03357.21 ORY16694.1 - 3.3e-18 65.9 15.4 3.3e-18 65.9 15.4 2.4 1 1 1 2 2 2 1 Snf7 PCEMA1 PF07418.11 ORY16694.1 - 5.2 6.5 16.1 10 5.6 16.1 1.4 1 0 0 1 1 1 0 Acidic phosphoprotein precursor PCEMA1 ATP_bind_1 PF03029.17 ORY16695.1 - 3.4e-75 252.9 0.0 5.5e-75 252.3 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_31 PF13614.6 ORY16695.1 - 0.0014 18.6 0.0 1.6 8.6 0.0 2.3 1 1 1 2 2 2 2 AAA domain CLP1_P PF16575.5 ORY16695.1 - 0.0049 16.7 0.0 0.0093 15.8 0.0 1.4 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_29 PF13555.6 ORY16695.1 - 0.0049 16.6 0.0 0.01 15.6 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 ORY16695.1 - 0.0059 17.0 0.0 0.1 12.9 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 ORY16695.1 - 0.012 16.2 1.1 0.28 11.7 0.1 2.7 2 1 0 2 2 2 0 AAA domain MeaB PF03308.16 ORY16695.1 - 0.014 14.4 0.1 0.03 13.3 0.0 1.6 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB RuvB_N PF05496.12 ORY16695.1 - 0.032 14.0 0.0 0.057 13.2 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 ORY16695.1 - 0.041 14.0 0.0 0.098 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 ORY16695.1 - 0.049 14.0 0.0 0.14 12.5 0.0 1.8 2 0 0 2 2 2 0 RNA helicase KTI12 PF08433.10 ORY16695.1 - 0.049 13.1 0.0 0.074 12.5 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_22 PF13401.6 ORY16695.1 - 0.064 13.5 0.0 0.15 12.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain Fer4_NifH PF00142.18 ORY16695.1 - 0.069 12.6 0.1 0.33 10.4 0.1 1.9 1 1 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_17 PF13207.6 ORY16695.1 - 0.093 13.2 0.0 0.3 11.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain WD40 PF00400.32 ORY16696.1 - 1.9e-13 50.7 5.3 0.022 15.6 0.3 5.4 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY16696.1 - 0.00033 20.9 0.0 2.1 8.7 0.0 3.5 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Importin_rep PF18773.1 ORY16696.1 - 0.35 10.6 2.8 0.86 9.4 0.2 2.7 3 0 0 3 3 3 0 Importin 13 repeat RNase_P_Rpp14 PF01900.19 ORY16698.1 - 4.6e-34 116.7 0.0 6.6e-34 116.3 0.0 1.2 1 0 0 1 1 1 1 Rpp14/Pop5 family Synaptobrevin PF00957.21 ORY16699.1 - 3.4e-33 113.3 0.0 4.7e-33 112.8 0.0 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 ORY16699.1 - 1.8e-28 98.4 0.1 3.1e-28 97.6 0.1 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain DUF5542 PF17696.1 ORY16699.1 - 0.72 10.0 2.6 0.7 10.1 0.5 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5542) Prominin PF05478.11 ORY16699.1 - 3.4 5.5 4.3 4.2 5.2 0.0 2.0 1 1 0 2 2 2 0 Prominin CPSase_L_D2 PF02786.17 ORY16700.1 - 5.5e-114 378.9 0.3 5.9e-83 277.5 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain GATase PF00117.28 ORY16700.1 - 9.7e-48 162.5 0.0 3.4e-47 160.7 0.0 1.9 2 0 0 2 2 2 1 Glutamine amidotransferase class-I OTCace_N PF02729.21 ORY16700.1 - 6e-47 159.4 0.0 1.3e-46 158.2 0.0 1.7 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_sm_chain PF00988.22 ORY16700.1 - 1.3e-46 157.6 0.0 3e-46 156.4 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain CPSase_L_D3 PF02787.19 ORY16700.1 - 7.2e-40 136.1 0.0 1.6e-39 135.0 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace PF00185.24 ORY16700.1 - 1.3e-33 116.3 0.0 2.5e-33 115.4 0.0 1.5 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain MGS PF02142.22 ORY16700.1 - 1.2e-20 73.5 0.0 6.2e-19 68.0 0.0 3.3 2 0 0 2 2 2 1 MGS-like domain Dala_Dala_lig_C PF07478.13 ORY16700.1 - 3.1e-18 66.1 0.5 1.9e-09 37.4 0.1 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 ORY16700.1 - 2e-16 60.1 0.1 1.3e-07 31.4 0.0 3.1 3 0 0 3 3 3 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 ORY16700.1 - 2e-09 37.3 0.0 7.8e-05 22.4 0.0 2.8 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.14 ORY16700.1 - 1.6e-05 25.0 0.3 0.088 12.8 0.0 2.9 3 0 0 3 3 3 2 ATP-grasp domain Peptidase_C26 PF07722.13 ORY16700.1 - 1.8e-05 24.6 0.1 0.0022 17.8 0.1 2.5 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.24 ORY16700.1 - 3e-05 23.9 0.1 0.004 17.0 0.0 3.8 4 0 0 4 4 4 1 DJ-1/PfpI family GARS_A PF01071.19 ORY16700.1 - 0.0025 17.6 0.2 3.5 7.4 0.0 2.8 3 0 0 3 3 3 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Ion_trans PF00520.31 ORY16701.1 - 4.8e-09 35.8 27.4 9e-09 34.9 27.4 1.4 1 0 0 1 1 1 1 Ion transport protein TetR_C_31 PF17940.1 ORY16701.1 - 2 8.7 5.0 0.56 10.4 0.9 2.3 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Glyco_hydro_15 PF00723.21 ORY16702.1 - 1.7e-74 251.2 0.0 2e-74 251.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 Glyco_hydro_7 PF00840.20 ORY16703.1 - 2.9e-199 662.3 21.7 3.2e-199 662.1 21.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 FlaE PF07559.14 ORY16703.1 - 0.05 14.2 2.0 0.062 13.9 0.6 1.9 2 0 0 2 2 2 0 Flagellar basal body protein FlaE HET PF06985.11 ORY16704.1 - 1.2e-08 35.4 0.0 3.2e-08 34.1 0.0 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) CBP PF12192.8 ORY16704.1 - 0.13 12.5 0.1 0.26 11.5 0.1 1.4 1 0 0 1 1 1 0 Fungal calcium binding protein Shugoshin_N PF07558.11 ORY16705.1 - 0.029 14.2 0.5 0.076 12.9 0.5 1.7 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region SOGA PF11365.8 ORY16705.1 - 0.031 15.4 0.8 0.056 14.6 0.8 1.5 1 0 0 1 1 1 0 Protein SOGA Patatin PF01734.22 ORY16706.1 - 4.6e-22 79.2 0.0 6.8e-21 75.4 0.0 2.3 1 1 0 1 1 1 1 Patatin-like phospholipase GCR1_C PF12550.8 ORY16706.1 - 0.046 14.0 0.2 0.16 12.3 0.1 2.0 2 0 0 2 2 2 0 Transcriptional activator of glycolytic enzymes zf-Di19 PF05605.12 ORY16706.1 - 0.14 12.5 0.0 0.4 11.0 0.0 1.8 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Ligase_CoA PF00549.19 ORY16707.1 - 1.4e-35 122.3 0.6 1.4e-16 60.7 0.4 2.4 2 0 0 2 2 2 2 CoA-ligase CoA_binding PF02629.19 ORY16707.1 - 1.5e-17 64.0 0.5 1.5e-17 64.0 0.5 2.0 2 0 0 2 2 2 1 CoA binding domain Succ_CoA_lig PF13607.6 ORY16707.1 - 6.6e-09 35.7 0.5 1.9e-07 31.0 0.1 2.7 2 1 1 3 3 3 1 Succinyl-CoA ligase like flavodoxin domain ATP-grasp_2 PF08442.10 ORY16707.1 - 0.037 13.6 0.0 0.31 10.6 0.0 2.4 3 0 0 3 3 3 0 ATP-grasp domain KilA-N PF04383.13 ORY16708.1 - 0.0078 16.1 0.0 0.02 14.7 0.0 1.7 1 0 0 1 1 1 1 KilA-N domain Hamartin PF04388.12 ORY16708.1 - 0.47 9.1 7.8 0.53 8.9 7.8 1.0 1 0 0 1 1 1 0 Hamartin protein Rho_GDI PF02115.17 ORY16709.1 - 2.7e-60 203.5 0.6 3.2e-60 203.2 0.6 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor Adaptin_N PF01602.20 ORY16711.1 - 1.3e-95 321.0 0.0 1.8e-95 320.5 0.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 ORY16711.1 - 4.6e-15 56.0 0.0 4.5e-14 52.8 0.0 2.5 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 ORY16711.1 - 2.2e-07 31.2 6.6 0.00047 20.5 0.0 4.8 3 2 2 5 5 5 2 HEAT repeats HEAT PF02985.22 ORY16711.1 - 4.7e-05 23.3 2.8 6.1 7.4 0.0 5.9 7 0 0 7 7 7 2 HEAT repeat EH_Signature PF15611.6 ORY16711.1 - 0.0019 17.7 0.0 0.004 16.6 0.0 1.5 1 0 0 1 1 1 1 EH_Signature domain HEAT_EZ PF13513.6 ORY16711.1 - 0.12 13.0 2.4 16 6.1 0.0 4.6 4 1 1 5 5 5 0 HEAT-like repeat NOG1_N PF17835.1 ORY16711.1 - 0.16 12.0 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 NOG1 N-terminal helical domain RNA_pol_3_Rpc31 PF11705.8 ORY16711.1 - 4.2 7.6 20.6 0.3 11.3 15.1 1.8 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Metallophos PF00149.28 ORY16713.1 - 9.9e-37 127.4 0.5 1.3e-36 127.0 0.5 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 ORY16713.1 - 0.021 15.2 0.6 0.055 13.9 0.6 1.7 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Metallophos_2 PF12850.7 ORY16713.1 - 0.026 14.7 0.0 0.045 13.9 0.0 1.4 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain PRK PF00485.18 ORY16714.1 - 4.1e-58 196.4 0.0 5.5e-58 195.9 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.6 ORY16714.1 - 6.7e-41 140.0 0.0 9.7e-41 139.5 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase CPT PF07931.12 ORY16714.1 - 7.6e-06 25.9 0.0 1.5e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_18 PF13238.6 ORY16714.1 - 0.003 18.1 0.0 0.0054 17.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 ORY16714.1 - 0.028 14.8 0.0 0.077 13.4 0.0 1.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 ORY16714.1 - 0.032 13.5 0.0 0.055 12.7 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_24 PF13479.6 ORY16714.1 - 0.04 13.6 0.0 0.063 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 ORY16714.1 - 0.043 13.0 0.0 0.069 12.3 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain ABC_tran PF00005.27 ORY16714.1 - 0.065 13.8 0.9 0.2 12.2 0.4 1.9 2 0 0 2 2 2 0 ABC transporter AAA_33 PF13671.6 ORY16714.1 - 0.16 12.1 0.0 0.49 10.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 ORY16714.1 - 0.19 11.8 0.0 5 7.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_17 PF13207.6 ORY16714.1 - 0.2 12.1 0.3 2.5 8.5 0.3 2.3 1 1 0 1 1 1 0 AAA domain CLTH PF10607.9 ORY16715.1 - 8.8e-31 106.8 0.1 1e-30 106.6 0.1 1.1 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 ORY16715.1 - 2e-05 24.4 0.0 4.7e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 LisH Dec-1 PF04624.14 ORY16715.1 - 0.15 11.9 0.2 0.28 11.1 0.2 1.4 1 0 0 1 1 1 0 Dec-1 repeat Barttin PF15462.6 ORY16717.1 - 0.0067 16.2 0.3 0.01 15.6 0.3 1.3 1 0 0 1 1 1 1 Bartter syndrome, infantile, with sensorineural deafness (Barttin) UBM PF14377.6 ORY16717.1 - 0.17 11.4 0.3 0.54 9.8 0.1 2.0 2 0 0 2 2 2 0 Ubiquitin binding region Acetyltransf_7 PF13508.7 ORY16718.1 - 3.6e-07 30.5 0.0 6.2e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ORY16718.1 - 5.6e-07 29.5 0.0 8.5e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 ORY16718.1 - 4.9e-06 26.6 0.1 5.9e-05 23.2 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORY16718.1 - 7.4e-06 26.2 0.0 1.3e-05 25.4 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family FR47 PF08445.10 ORY16718.1 - 0.00061 19.7 0.0 0.0012 18.8 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 ORY16718.1 - 0.063 13.4 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase GNAT_acetyltran PF12746.7 ORY16718.1 - 0.08 12.5 0.0 0.19 11.3 0.0 1.6 2 0 0 2 2 2 0 GNAT acetyltransferase NUDIX PF00293.28 ORY16720.1 - 4.1e-26 91.6 0.0 5.9e-26 91.0 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain HMGL-like PF00682.19 ORY16721.1 - 8.9e-80 268.0 0.1 1.3e-79 267.5 0.1 1.2 1 0 0 1 1 1 1 HMGL-like GFA PF04828.14 ORY16722.1 - 1.5e-12 47.7 0.5 2.3e-12 47.1 0.5 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zf-C3HC4_3 PF13920.6 ORY16723.1 - 5.6e-08 32.5 11.7 8.5e-08 31.9 11.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 ORY16723.1 - 0.012 15.4 10.8 0.021 14.7 10.8 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 F-box PF00646.33 ORY16724.1 - 2.4e-09 36.9 0.1 4.7e-09 35.9 0.1 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 ORY16724.1 - 2.9e-08 33.5 0.2 4.9e-08 32.7 0.2 1.4 1 0 0 1 1 1 1 F-box-like UIM PF02809.20 ORY16724.1 - 9.5 6.4 16.6 2.5 8.2 1.3 3.8 3 0 0 3 3 3 0 Ubiquitin interaction motif ERG2_Sigma1R PF04622.12 ORY16725.1 - 1.1e-93 312.3 0.2 1.3e-93 312.1 0.2 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein DEAD PF00270.29 ORY16726.1 - 7.5e-11 42.1 0.0 1.1e-10 41.6 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase MFS_1 PF07690.16 ORY16727.1 - 1.1e-43 149.5 32.2 6.7e-38 130.5 25.4 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY16727.1 - 0.00015 20.7 9.4 0.00015 20.7 9.4 2.7 3 0 0 3 3 3 1 Sugar (and other) transporter LacY_symp PF01306.19 ORY16727.1 - 0.013 14.3 0.6 0.013 14.3 0.6 3.0 3 1 1 4 4 4 0 LacY proton/sugar symporter RhodobacterPufX PF11511.8 ORY16727.1 - 0.11 12.1 0.3 1.1 8.9 0.3 2.7 1 0 0 1 1 1 0 Intrinsic membrane protein PufX MFS_1_like PF12832.7 ORY16727.1 - 0.57 9.0 16.1 0.56 9.0 0.6 3.9 3 1 1 4 4 4 0 MFS_1 like family Par3_HAL_N_term PF12053.8 ORY16728.1 - 0.14 12.3 0.3 0.31 11.3 0.0 1.6 2 0 0 2 2 2 0 N-terminal of Par3 and HAL proteins RRM_1 PF00076.22 ORY16729.1 - 4.1e-20 71.4 0.5 6.8e-09 35.4 0.0 2.6 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 ORY16729.1 - 0.071 13.2 0.0 2.9 8.1 0.0 2.6 2 1 0 2 2 2 0 RNA recognition motif Cluap1 PF10234.9 ORY16729.1 - 0.072 12.5 2.4 0.12 11.7 2.4 1.3 1 0 0 1 1 1 0 Clusterin-associated protein-1 ATP-synt_D PF01813.17 ORY16730.1 - 7.3e-72 241.3 1.3 9.6e-72 240.9 1.3 1.1 1 0 0 1 1 1 1 ATP synthase subunit D CobA_CobO_BtuR PF02572.15 ORY16730.1 - 0.2 11.9 2.9 0.64 10.3 0.1 2.4 2 1 1 3 3 3 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP PHM7_cyt PF14703.6 ORY16730.1 - 1.3 9.2 5.3 4.3 7.5 1.4 2.3 2 1 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter TPR_14 PF13428.6 ORY16731.1 - 3.9e-12 45.9 17.4 4.9 8.2 0.3 12.1 10 2 2 12 12 12 1 Tetratricopeptide repeat Suf PF05843.14 ORY16731.1 - 2e-09 37.9 7.8 0.076 13.0 0.1 5.8 3 1 2 5 5 5 3 Suppressor of forked protein (Suf) TPR_15 PF13429.6 ORY16731.1 - 1.6e-06 27.5 2.1 0.043 13.0 0.1 4.2 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 ORY16731.1 - 2.1e-05 24.4 10.9 0.19 12.0 0.0 7.6 8 0 0 8 8 8 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 ORY16731.1 - 6.5e-05 22.9 13.8 0.46 10.5 0.1 7.0 6 1 0 6 6 6 2 Mad3/BUB1 homology region 1 TPR_19 PF14559.6 ORY16731.1 - 9.1e-05 22.9 0.1 3.4 8.3 0.1 5.3 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 ORY16731.1 - 9.5e-05 22.2 13.4 0.16 12.2 0.0 7.8 9 0 0 9 9 8 1 Tetratricopeptide repeat SNAP PF14938.6 ORY16731.1 - 9.8e-05 21.9 5.1 0.64 9.4 0.1 4.8 5 1 1 6 6 6 1 Soluble NSF attachment protein, SNAP MIT PF04212.18 ORY16731.1 - 0.0087 16.1 0.1 5.4 7.2 0.0 4.5 4 0 0 4 4 4 1 MIT (microtubule interacting and transport) domain NRDE-2 PF08424.10 ORY16731.1 - 0.026 13.7 12.7 0.089 11.9 0.3 5.2 3 3 0 4 4 4 0 NRDE-2, necessary for RNA interference TPR_17 PF13431.6 ORY16731.1 - 0.041 14.3 4.5 10 6.8 0.0 6.2 7 0 0 7 7 6 0 Tetratricopeptide repeat RPN7 PF10602.9 ORY16731.1 - 0.045 13.5 0.7 0.43 10.3 0.3 2.8 2 1 0 2 2 2 0 26S proteasome subunit RPN7 TPR_12 PF13424.6 ORY16731.1 - 0.13 12.5 10.7 35 4.8 0.1 6.9 8 0 0 8 8 7 0 Tetratricopeptide repeat APOBEC_C PF05240.14 ORY16731.1 - 0.4 10.7 2.5 0.72 9.8 0.1 2.6 2 0 0 2 2 2 0 APOBEC-like C-terminal domain FF PF01846.19 ORY16731.1 - 0.75 10.0 3.9 13 6.1 0.3 3.5 3 0 0 3 3 3 0 FF domain TPR_6 PF13174.6 ORY16731.1 - 1.1 10.1 13.4 50 4.8 0.0 7.5 10 0 0 10 10 8 0 Tetratricopeptide repeat HAT PF02184.16 ORY16731.1 - 6.9 6.7 12.9 4.1 7.4 0.1 5.9 6 0 0 6 6 6 0 HAT (Half-A-TPR) repeat Kei1 PF08552.11 ORY16733.1 - 4.7e-60 202.7 5.5 5.7e-60 202.5 5.5 1.1 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 adh_short_C2 PF13561.6 ORY16734.1 - 2.3e-30 105.9 0.1 6.4e-29 101.2 0.1 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY16734.1 - 3.8e-24 85.2 0.1 2.7e-22 79.2 0.1 2.1 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORY16734.1 - 0.0054 16.7 0.1 0.0095 15.9 0.1 1.5 1 1 0 1 1 1 1 KR domain Dicistro_VP4 PF11492.8 ORY16734.1 - 0.019 14.9 0.3 4.3 7.4 0.0 2.6 2 0 0 2 2 2 0 Cricket paralysis virus, VP4 SUV3_C PF12513.8 ORY16735.1 - 3.1e-19 68.6 0.9 8.1e-19 67.3 0.9 1.8 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.31 ORY16735.1 - 3.2e-10 40.3 0.0 7.4e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Suv3_C_1 PF18147.1 ORY16735.1 - 4.5e-10 39.2 0.1 9e-10 38.3 0.1 1.5 1 0 0 1 1 1 1 Suv3 C-terminal domain 1 DUF4771 PF15995.5 ORY16735.1 - 0.083 13.1 0.1 0.24 11.7 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4771) Sec1 PF00995.23 ORY16736.1 - 1.6e-119 400.8 0.0 1.8e-119 400.6 0.0 1.0 1 0 0 1 1 1 1 Sec1 family DIM1 PF02966.16 ORY16737.1 - 3.3e-56 188.7 0.1 5.2e-40 136.3 0.0 2.0 1 1 1 2 2 2 2 Mitosis protein DIM1 F-box-like PF12937.7 ORY16738.1 - 0.013 15.3 0.1 0.044 13.7 0.0 1.9 2 0 0 2 2 2 0 F-box-like Ribonuclease_3 PF00636.26 ORY16739.1 - 7.5e-38 129.4 0.0 7.6e-19 68.3 0.0 3.0 2 0 0 2 2 2 2 Ribonuclease III domain Dicer_dimer PF03368.14 ORY16739.1 - 3.5e-23 81.6 0.1 2.4e-22 78.9 0.1 2.5 3 0 0 3 3 3 1 Dicer dimerisation domain Ribonucleas_3_3 PF14622.6 ORY16739.1 - 3.5e-20 72.5 0.0 2.6e-08 34.1 0.0 3.8 2 2 0 2 2 2 2 Ribonuclease-III-like Helicase_C PF00271.31 ORY16739.1 - 6.5e-16 58.7 0.0 1.6e-15 57.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY16739.1 - 5.1e-12 46.1 0.2 1.1e-11 45.0 0.2 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 ORY16739.1 - 5e-11 42.7 0.0 1.1e-10 41.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Microtub_bd PF16796.5 ORY16739.1 - 0.14 12.1 0.2 0.36 10.8 0.2 1.7 1 0 0 1 1 1 0 Microtubule binding TraT PF05818.12 ORY16739.1 - 0.26 11.0 1.5 0.55 9.9 1.5 1.5 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein TAP42 PF04177.12 ORY16740.1 - 1.2e-107 359.8 1.4 1.3e-107 359.6 1.4 1.0 1 0 0 1 1 1 1 TAP42-like family Terminase_4 PF05119.12 ORY16740.1 - 0.039 14.4 0.7 0.091 13.2 0.2 1.9 2 0 0 2 2 2 0 Phage terminase, small subunit DUF4011 PF13195.6 ORY16740.1 - 0.043 13.7 1.4 0.077 12.9 1.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4011) Lipase_GDSL_2 PF13472.6 ORY16741.1 - 6.5e-12 46.2 0.0 5e-11 43.3 0.0 2.0 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 ORY16741.1 - 3.2e-11 43.6 0.0 5e-11 43.0 0.0 1.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Hamartin PF04388.12 ORY16743.1 - 2.1e-16 59.8 34.5 2.1e-16 59.8 34.5 3.5 1 1 1 2 2 2 1 Hamartin protein NPV_P10 PF05531.12 ORY16743.1 - 0.2 12.1 1.1 0.9 10.0 0.6 2.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF3584 PF12128.8 ORY16743.1 - 1.1 6.6 34.9 2.4 5.5 34.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF2390 PF09523.10 ORY16744.1 - 0.066 13.5 0.3 0.07 13.5 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2390) Mlh1_C PF16413.5 ORY16746.1 - 3.7e-99 331.5 0.0 5.3e-99 331.0 0.0 1.2 1 0 0 1 1 1 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 ORY16746.1 - 1.1e-35 121.9 0.0 1.8e-35 121.2 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 ORY16746.1 - 6.7e-14 51.9 0.0 1.3e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 ORY16746.1 - 4.2e-07 30.5 0.0 9.6e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PEP_mutase PF13714.6 ORY16748.1 - 7e-62 209.0 0.1 7.9e-62 208.8 0.1 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase DUF2293 PF10056.9 ORY16749.1 - 1.8e-27 95.4 0.5 4.6e-27 94.1 0.1 2.0 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2293) Complex1_LYR PF05347.15 ORY16750.1 - 0.00024 21.1 1.4 0.00041 20.3 1.4 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) HTH_Tnp_1 PF01527.20 ORY16750.1 - 0.0092 16.3 0.5 0.15 12.4 0.1 2.1 1 1 1 2 2 2 1 Transposase Complex1_LYR_2 PF13233.6 ORY16750.1 - 0.014 16.1 0.3 0.02 15.6 0.3 1.3 1 1 0 1 1 1 0 Complex1_LYR-like NFACT-R_1 PF05670.13 ORY16751.1 - 2.9e-42 143.7 0.1 4.5e-42 143.1 0.1 1.3 1 0 0 1 1 1 1 NFACT protein RNA binding domain NFACT-R_2 PF18297.1 ORY16751.1 - 0.022 14.9 0.1 0.11 12.7 0.0 2.1 1 1 1 2 2 2 0 NFACT protein RNA binding domain DDRGK PF09756.9 ORY16751.1 - 0.93 9.1 16.5 1.5 8.4 16.5 1.4 1 0 0 1 1 1 0 DDRGK domain Svf1_C PF17187.4 ORY16752.1 - 5.8e-59 198.6 0.0 9.4e-59 197.9 0.0 1.4 1 0 0 1 1 1 1 Svf1-like C-terminal lipocalin-like domain Svf1 PF08622.10 ORY16752.1 - 5.8e-53 179.3 0.0 8.3e-53 178.8 0.0 1.2 1 0 0 1 1 1 1 Svf1-like N-terminal lipocalin domain Pkinase PF00069.25 ORY16753.1 - 3.2e-50 170.9 0.0 1.4e-49 168.9 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY16753.1 - 2.5e-23 82.7 0.0 5.8e-23 81.5 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 ORY16753.1 - 0.0074 16.2 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 ORY16753.1 - 0.02 13.9 0.0 0.034 13.1 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Kinase-like PF14531.6 ORY16753.1 - 0.033 13.5 0.0 0.1 11.9 0.0 1.7 2 0 0 2 2 2 0 Kinase-like SAB PF04382.13 ORY16753.1 - 0.048 13.8 0.4 0.14 12.3 0.4 1.8 1 0 0 1 1 1 0 SAB domain Neur_chan_memb PF02932.16 ORY16753.1 - 3.6 7.6 4.1 24 4.9 0.2 2.6 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Acetyltransf_1 PF00583.25 ORY16757.1 - 1.8e-09 37.8 0.1 3.8e-09 36.8 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ORY16757.1 - 0.0027 18.1 0.1 0.022 15.2 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Pho86 PF11124.8 ORY16757.1 - 0.032 13.7 0.1 0.041 13.3 0.1 1.1 1 0 0 1 1 1 0 Inorganic phosphate transporter Pho86 Acetyltransf_CG PF14542.6 ORY16757.1 - 0.14 12.3 0.2 0.32 11.2 0.2 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_10 PF13673.7 ORY16757.1 - 0.15 12.0 0.1 0.3 11.0 0.1 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain MOZART1 PF12554.8 ORY16758.1 - 1.6e-23 82.2 0.4 1.9e-23 82.0 0.4 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated DnaB_bind PF10410.9 ORY16758.1 - 0.065 13.4 0.2 11 6.4 0.0 2.2 2 0 0 2 2 2 0 DnaB-helicase binding domain of primase DHHA1 PF02272.19 ORY16758.1 - 0.11 13.0 0.0 0.14 12.6 0.0 1.2 1 0 0 1 1 1 0 DHHA1 domain CENP-T_C PF15511.6 ORY16759.1 - 0.088 12.9 0.0 0.17 12.0 0.0 1.5 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold UbiA PF01040.18 ORY16760.1 - 1.3e-21 77.1 8.5 1.9e-21 76.5 8.5 1.3 1 0 0 1 1 1 1 UbiA prenyltransferase family Chromate_transp PF02417.15 ORY16761.1 - 0.064 13.4 0.8 1.2 9.3 0.0 2.2 2 1 0 2 2 2 0 Chromate transporter NUC153 PF08159.12 ORY16762.1 - 2.9e-14 52.6 1.1 2.9e-14 52.6 1.1 5.1 5 0 0 5 5 5 3 NUC153 domain Metallophos PF00149.28 ORY16763.1 - 4e-32 112.4 0.0 4.9e-23 82.7 0.0 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase STPPase_N PF16891.5 ORY16763.1 - 0.084 13.3 0.1 0.21 12.1 0.1 1.6 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain PAP1 PF08601.10 ORY16763.1 - 4.3 7.0 6.5 6.1 6.5 6.5 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 COA2 PF17051.5 ORY16764.1 - 7.3e-05 22.8 0.0 0.0001 22.3 0.0 1.3 1 0 0 1 1 1 1 Cytochrome C oxidase assembly factor 2 RNA_pol_Rpc4 PF05132.14 ORY16764.1 - 0.077 13.4 0.4 0.094 13.1 0.4 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 Ras PF00071.22 ORY16766.1 - 7.4e-60 201.2 0.2 8.8e-60 201.0 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY16766.1 - 1.9e-20 73.3 0.0 3.1e-20 72.6 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY16766.1 - 4.5e-09 36.0 0.0 5.1e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 ORY16766.1 - 1.4e-06 27.9 0.3 7.6e-06 25.6 0.3 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 ORY16766.1 - 7.5e-05 22.3 0.0 0.00013 21.6 0.0 1.4 1 1 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 ORY16766.1 - 9.3e-05 22.4 0.5 0.32 10.9 0.0 2.4 1 1 1 3 3 3 2 RsgA GTPase MMR_HSR1 PF01926.23 ORY16766.1 - 0.0019 18.3 0.0 0.0032 17.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 ORY16766.1 - 0.0023 17.9 0.0 0.0049 16.9 0.0 1.6 1 1 0 1 1 1 1 C-terminal region of MMR_HSR1 domain ATP_bind_1 PF03029.17 ORY16766.1 - 0.058 13.2 2.4 0.41 10.4 0.1 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein MoCF_biosynth PF00994.24 ORY16767.1 - 1.6e-33 115.4 0.0 2.7e-33 114.6 0.0 1.3 1 0 0 1 1 1 1 Probable molybdopterin binding domain CinA_KH PF18146.1 ORY16767.1 - 0.02 15.0 0.0 0.051 13.7 0.0 1.7 1 0 0 1 1 1 0 Damage-inducible protein CinA KH domain Cofilin_ADF PF00241.20 ORY16768.1 - 2.5e-18 66.1 0.0 2.8e-18 65.9 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein SAPIS-gp6 PF16722.5 ORY16768.1 - 0.072 13.5 0.2 0.16 12.4 0.0 1.6 2 0 0 2 2 2 0 Pathogenicity island protein gp6 in Staphylococcus RRM_1 PF00076.22 ORY16769.1 - 9.7e-23 79.8 0.0 8.7e-12 44.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FAD_binding_1 PF00667.20 ORY16771.1 - 2.9e-65 220.0 0.0 4.3e-65 219.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 ORY16771.1 - 2.7e-35 121.7 1.2 2.7e-35 121.7 1.2 2.2 3 0 0 3 3 3 1 Flavodoxin NAD_binding_1 PF00175.21 ORY16771.1 - 4.2e-21 75.6 0.0 6.2e-20 71.9 0.0 2.5 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Beta-Casp PF10996.8 ORY16771.1 - 0.012 15.9 0.1 0.046 14.0 0.0 2.0 2 0 0 2 2 2 0 Beta-Casp domain MOR2-PAG1_N PF14222.6 ORY16772.1 - 3.7e-206 686.3 0.0 6.7e-206 685.5 0.0 1.4 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.6 ORY16772.1 - 1.4e-93 313.4 0.4 2.6e-92 309.3 0.0 3.1 3 0 0 3 3 3 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.6 ORY16772.1 - 3.5e-36 124.3 5.8 4.5e-14 51.1 0.0 4.1 3 1 1 4 4 4 4 Cell morphogenesis central region GATA PF00320.27 ORY16773.1 - 6.3e-29 99.3 17.8 5e-15 54.8 3.5 2.5 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 ORY16773.1 - 8.5e-08 31.6 4.1 0.00017 21.0 0.3 2.4 2 0 0 2 2 2 2 TFIIB zinc-binding Zn-ribbon_8 PF09723.10 ORY16773.1 - 2.8e-05 24.1 2.6 0.062 13.4 0.2 2.8 2 0 0 2 2 2 2 Zinc ribbon domain zf-RRN7 PF11781.8 ORY16773.1 - 0.00055 19.6 6.5 0.019 14.7 0.5 2.6 2 0 0 2 2 2 2 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Auto_anti-p27 PF06677.12 ORY16773.1 - 0.002 18.2 6.5 0.08 13.1 0.9 2.5 2 0 0 2 2 2 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) ArfGap PF01412.18 ORY16773.1 - 0.0085 16.2 2.7 1.6 8.8 0.2 2.4 2 0 0 2 2 2 2 Putative GTPase activating protein for Arf DUF2387 PF09526.10 ORY16773.1 - 0.013 15.6 0.5 3.3 7.9 0.1 2.6 2 0 0 2 2 2 0 Probable metal-binding protein (DUF2387) OrfB_Zn_ribbon PF07282.11 ORY16773.1 - 0.016 15.1 10.4 0.023 14.6 0.8 2.7 3 0 0 3 3 3 0 Putative transposase DNA-binding domain zf-Sec23_Sec24 PF04810.15 ORY16773.1 - 0.059 13.4 0.8 0.059 13.4 0.8 3.4 4 0 0 4 4 3 0 Sec23/Sec24 zinc finger DZR PF12773.7 ORY16773.1 - 0.14 12.2 11.8 0.99 9.5 0.8 3.2 2 1 1 3 3 3 0 Double zinc ribbon NMD3 PF04981.13 ORY16773.1 - 0.2 11.1 0.6 11 5.4 0.0 2.2 2 0 0 2 2 2 0 NMD3 family TDP43_N PF18694.1 ORY16773.1 - 0.2 11.5 0.1 1.7 8.6 0.0 2.2 2 0 0 2 2 2 0 Transactive response DNA-binding protein N-terminal domain eIF-5_eIF-2B PF01873.17 ORY16773.1 - 0.33 10.8 5.2 7.3 6.5 0.4 2.4 2 0 0 2 2 2 0 Domain found in IF2B/IF5 ADK_lid PF05191.14 ORY16773.1 - 4.1 7.5 5.6 4.4 7.4 0.4 3.5 3 0 0 3 3 3 0 Adenylate kinase, active site lid Rubredoxin_2 PF18073.1 ORY16773.1 - 5.4 6.8 9.9 26 4.6 0.1 4.4 4 0 0 4 4 4 0 Rubredoxin metal binding domain Nudix_N_2 PF14803.6 ORY16773.1 - 7.1 6.6 11.1 12 5.9 1.5 3.1 2 1 0 2 2 2 0 Nudix N-terminal COPI_assoc PF08507.10 ORY16774.1 - 7.7e-33 113.3 4.6 8.6e-33 113.2 4.6 1.1 1 0 0 1 1 1 1 COPI associated protein CBP_BcsF PF11120.8 ORY16774.1 - 0.047 13.8 0.3 0.13 12.4 0.1 1.9 1 1 1 2 2 2 0 Cellulose biosynthesis protein BcsF DUF2583 PF10762.9 ORY16774.1 - 0.062 13.7 1.8 1.7 9.1 0.0 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF2583) DUF3096 PF11295.8 ORY16774.1 - 1.1 8.9 10.0 0.35 10.6 0.5 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3096) DUF2964 PF11177.8 ORY16774.1 - 3.1 8.1 7.0 0.45 10.7 2.5 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2964) IF-2B PF01008.17 ORY16775.1 - 3.8e-54 183.8 0.0 4.6e-54 183.5 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family Vac_Fusion PF02346.16 ORY16775.1 - 0.062 12.9 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Chordopoxvirus multifunctional envelope protein A27 YtxH PF12732.7 ORY16776.1 - 0.091 13.3 0.5 1.5 9.4 0.0 3.2 2 0 0 2 2 2 0 YtxH-like protein Lactamase_B PF00753.27 ORY16777.1 - 4.6e-14 52.9 0.4 3.3e-13 50.1 0.4 2.3 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 ORY16777.1 - 1.2e-05 24.9 0.0 2.1e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain AMP-binding PF00501.28 ORY16779.1 - 6.1e-78 262.3 0.0 7.4e-78 262.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORY16779.1 - 1.8e-17 64.1 0.8 9.5e-17 61.8 0.4 2.4 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DUF3533 PF12051.8 ORY16780.1 - 6.4e-73 245.8 15.6 8.6e-73 245.4 15.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) Glyco_hydro_79C PF16862.5 ORY16781.1 - 7.1e-20 71.8 1.3 7.1e-20 71.8 1.3 2.1 2 0 0 2 2 2 1 Glycosyl hydrolase family 79 C-terminal beta domain Luteo_coat PF00894.18 ORY16781.1 - 0.096 12.6 1.8 7 6.5 0.8 2.4 2 0 0 2 2 2 0 Luteovirus coat protein Peptidase_C48 PF02902.19 ORY16783.1 - 7.8e-15 55.3 0.0 1.6e-14 54.3 0.0 1.5 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Metallophos PF00149.28 ORY16784.1 - 3.5e-38 132.1 0.5 5.9e-38 131.4 0.5 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 ORY16784.1 - 0.021 15.3 0.0 0.042 14.3 0.0 1.5 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain MCM PF00493.23 ORY16785.1 - 2.1e-103 344.3 0.2 3.2e-103 343.6 0.2 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 ORY16785.1 - 3.9e-39 133.4 0.9 7.8e-39 132.4 0.9 1.5 1 0 0 1 1 1 1 MCM OB domain MCM6_C PF18263.1 ORY16785.1 - 1.7e-29 102.2 1.0 3.8e-29 101.1 1.0 1.6 1 0 0 1 1 1 1 MCM6 C-terminal winged-helix domain MCM_lid PF17855.1 ORY16785.1 - 6.6e-25 87.3 1.0 2.3e-24 85.6 0.3 2.4 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_N PF14551.6 ORY16785.1 - 2.7e-21 76.1 0.6 9.2e-21 74.4 0.3 2.1 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 ORY16785.1 - 1.8e-08 34.1 0.0 8.6e-07 28.5 0.0 2.8 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 ORY16785.1 - 0.0013 18.5 0.0 0.0032 17.2 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.11 ORY16785.1 - 0.0013 18.6 0.0 0.0029 17.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 ORY16785.1 - 0.0097 15.9 0.0 0.029 14.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Acyltransferase PF01553.21 ORY16786.1 - 1.7e-18 66.5 0.0 3.5e-18 65.5 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase WD40 PF00400.32 ORY16787.1 - 1.2e-08 35.4 8.5 0.13 13.1 0.2 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY16787.1 - 0.00043 20.5 0.0 0.0072 16.6 0.0 2.7 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Fungal_trans_2 PF11951.8 ORY16788.1 - 3.1e-11 42.7 1.5 3.1e-11 42.7 1.5 2.4 2 1 0 2 2 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY16788.1 - 2e-06 27.8 10.3 3.7e-06 27.0 10.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain EPL1 PF10513.9 ORY16788.1 - 0.031 14.7 10.4 0.065 13.6 10.4 1.5 1 0 0 1 1 1 0 Enhancer of polycomb-like MMR1 PF08505.10 ORY16788.1 - 0.21 11.8 13.2 0.4 10.9 13.2 1.3 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein TFIIA PF03153.13 ORY16788.1 - 0.36 10.8 30.3 0.035 14.1 22.1 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF2722 PF10846.8 ORY16788.1 - 0.43 9.5 19.5 0.75 8.7 19.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DUF908 PF06012.12 ORY16788.1 - 0.52 9.7 8.3 0.46 9.9 6.2 1.8 2 0 0 2 2 2 0 Domain of Unknown Function (DUF908) SKA1 PF07160.12 ORY16788.1 - 0.73 9.6 9.5 1.4 8.7 9.5 1.4 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 Neur_chan_memb PF02932.16 ORY16788.1 - 0.94 9.5 6.0 0.74 9.8 4.1 1.9 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region TMEM51 PF15345.6 ORY16788.1 - 2.9 7.7 13.2 5.9 6.7 13.2 1.4 1 0 0 1 1 1 0 Transmembrane protein 51 Ctr PF04145.15 ORY16788.1 - 7.4 7.2 8.0 69 4.0 4.5 3.0 3 0 0 3 3 3 0 Ctr copper transporter family ADH_zinc_N PF00107.26 ORY16790.1 - 1.5e-27 96.2 0.3 2.3e-27 95.5 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ORY16790.1 - 1.1e-12 49.1 0.0 3.4e-12 47.6 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ORY16790.1 - 2.6e-11 43.4 0.6 9.6e-11 41.5 0.0 2.2 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.18 ORY16790.1 - 0.00042 20.6 0.0 0.00086 19.6 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain ELFV_dehydrog PF00208.21 ORY16790.1 - 0.043 13.5 0.0 0.064 13.0 0.0 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase GDA1_CD39 PF01150.17 ORY16791.1 - 4.9e-106 354.9 0.0 6.8e-106 354.5 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family GATase PF00117.28 ORY16792.1 - 4.5e-12 46.1 0.0 7.3e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.14 ORY16792.1 - 0.0026 17.4 0.0 0.0035 17.0 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_C26 PF07722.13 ORY16792.1 - 0.042 13.6 0.0 23 4.6 0.0 3.0 3 0 0 3 3 3 0 Peptidase C26 MFS_1 PF07690.16 ORY16793.1 - 3e-38 131.7 63.1 1.3e-31 109.8 31.0 2.8 3 1 0 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.13 ORY16793.1 - 9.9e-07 27.6 20.0 1.4e-06 27.0 20.0 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) HD PF01966.22 ORY16794.1 - 2.3e-05 24.6 0.0 6.9e-05 23.1 0.0 1.8 2 0 0 2 2 2 1 HD domain Polysacc_synt_3 PF13440.6 ORY16794.1 - 0.12 11.6 0.0 0.28 10.3 0.0 1.6 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein SLAC1 PF03595.17 ORY16795.1 - 7.7e-87 291.6 58.4 8.7e-87 291.4 58.4 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel DUF5056 PF16479.5 ORY16795.1 - 0.063 13.5 0.2 0.063 13.5 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5056) Sulfotransfer_4 PF17784.1 ORY16798.1 - 8.6e-67 225.1 0.0 9.9e-67 224.9 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 ORY16798.1 - 0.0088 16.4 0.0 0.018 15.4 0.0 1.5 1 1 0 1 1 1 1 Sulfotransferase family zf-C2H2 PF00096.26 ORY16801.1 - 2.5e-06 27.6 12.3 0.00086 19.6 2.3 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY16801.1 - 0.0011 19.6 8.2 0.13 13.2 0.9 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger Chlam_PMP PF02415.17 ORY16801.1 - 0.09 13.3 0.1 15 6.3 0.0 2.5 2 0 0 2 2 2 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Sigma70_r4 PF04545.16 ORY16802.1 - 0.00078 18.9 0.0 0.0013 18.2 0.0 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_Tnp_4 PF13613.6 ORY16802.1 - 0.00086 19.0 0.0 0.0014 18.3 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease HTH_Crp_2 PF13545.6 ORY16802.1 - 0.00093 19.1 0.0 0.0016 18.4 0.0 1.3 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_23 PF13384.6 ORY16802.1 - 0.0016 18.2 0.0 0.0031 17.3 0.0 1.4 1 0 0 1 1 1 1 Homeodomain-like domain HTH_38 PF13936.6 ORY16802.1 - 0.011 15.4 0.0 0.026 14.3 0.0 1.6 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_28 PF13518.6 ORY16802.1 - 0.014 15.5 0.0 0.028 14.6 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain MarR_2 PF12802.7 ORY16802.1 - 0.026 14.4 0.0 0.052 13.4 0.0 1.5 1 0 0 1 1 1 0 MarR family CENP-B_N PF04218.13 ORY16802.1 - 0.064 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain MarR PF01047.22 ORY16802.1 - 0.074 13.0 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 MarR family HTH_11 PF08279.12 ORY16802.1 - 0.09 12.7 0.1 0.21 11.6 0.0 1.6 2 0 0 2 2 2 0 HTH domain Bac_DnaA_C PF08299.11 ORY16802.1 - 0.14 12.2 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial dnaA protein helix-turn-helix HTH_IclR PF09339.10 ORY16802.1 - 0.14 12.0 0.0 0.31 10.9 0.0 1.6 1 0 0 1 1 1 0 IclR helix-turn-helix domain Cytochrom_B562 PF07361.11 ORY16804.1 - 1.3 9.7 6.2 0.31 11.7 0.4 2.6 3 0 0 3 3 3 0 Cytochrome b562 DUF3083 PF11281.8 ORY16808.1 - 0.19 11.0 0.0 0.29 10.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3083) HABP4_PAI-RBP1 PF04774.15 ORY16808.1 - 0.88 10.4 5.1 0.41 11.5 1.9 2.1 1 1 1 2 2 2 0 Hyaluronan / mRNA binding family LEA_3 PF03242.13 ORY16809.1 - 0.12 13.1 0.0 0.29 11.9 0.0 1.7 1 0 0 1 1 1 0 Late embryogenesis abundant protein ketoacyl-synt PF00109.26 ORY16811.1 - 5.5e-72 242.4 0.0 8.7e-72 241.7 0.0 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 ORY16811.1 - 5.5e-47 160.8 0.0 1.2e-46 159.7 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.10 ORY16811.1 - 4.5e-44 150.5 0.0 8.6e-44 149.6 0.0 1.5 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 ORY16811.1 - 2.9e-40 138.4 0.0 5.9e-40 137.4 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 ORY16811.1 - 8.2e-31 106.5 0.0 3.2e-30 104.6 0.0 2.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 ORY16811.1 - 3e-18 66.4 0.0 7.4e-18 65.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY16811.1 - 7.2e-14 52.0 0.0 1.6e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY16811.1 - 6.3e-13 49.2 0.0 3.3e-12 47.0 0.0 2.4 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY16811.1 - 7e-13 48.6 0.0 1.3e-12 47.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY16811.1 - 8.7e-13 48.7 0.0 2.4e-12 47.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 ORY16811.1 - 5.8e-11 42.8 0.0 4.8e-10 39.9 0.0 2.4 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension PP-binding PF00550.25 ORY16811.1 - 1e-07 32.2 0.3 3.1e-07 30.6 0.3 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.25 ORY16811.1 - 2.2e-06 27.3 0.2 9.9e-06 25.1 0.0 2.2 3 0 0 3 3 3 1 short chain dehydrogenase Ubie_methyltran PF01209.18 ORY16811.1 - 5.6e-05 22.6 0.0 0.00011 21.7 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Thiolase_N PF00108.23 ORY16811.1 - 0.00046 19.6 0.2 0.00084 18.8 0.2 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain RrnaAD PF00398.20 ORY16811.1 - 0.00048 19.3 0.0 0.00089 18.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_16 PF10294.9 ORY16811.1 - 0.0015 18.3 0.0 0.0035 17.1 0.0 1.5 1 0 0 1 1 1 1 Lysine methyltransferase NodS PF05401.11 ORY16811.1 - 0.013 15.2 0.1 0.029 14.0 0.1 1.5 1 0 0 1 1 1 0 Nodulation protein S (NodS) MTS PF05175.14 ORY16811.1 - 0.019 14.5 0.0 0.086 12.4 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase small domain DREV PF05219.12 ORY16811.1 - 0.021 13.9 0.0 0.038 13.1 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase NNMT_PNMT_TEMT PF01234.17 ORY16811.1 - 0.049 12.8 0.0 1.9 7.6 0.0 2.5 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family ApbA PF02558.16 ORY16812.1 - 3e-29 101.6 0.0 4.8e-29 101.0 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 ORY16812.1 - 6e-25 87.9 0.0 1.5e-24 86.6 0.0 1.6 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA C terminal GMC_oxred_N PF00732.19 ORY16812.1 - 0.059 12.7 0.0 0.09 12.1 0.0 1.3 1 0 0 1 1 1 0 GMC oxidoreductase DAO PF01266.24 ORY16812.1 - 0.06 12.9 0.0 0.088 12.4 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase ThiF PF00899.21 ORY16812.1 - 0.15 11.4 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 ThiF family PLA2_B PF01735.18 ORY16813.1 - 3.8e-24 85.0 0.0 7.1e-24 84.1 0.0 1.4 1 0 0 1 1 1 1 Lysophospholipase catalytic domain Exo70 PF03081.15 ORY16816.1 - 7.6e-88 295.1 0.0 1.3e-87 294.4 0.0 1.4 1 0 0 1 1 1 1 Exo70 exocyst complex subunit Chlorosome_CsmC PF11098.8 ORY16816.1 - 0.081 12.9 0.1 0.48 10.4 0.0 2.2 2 0 0 2 2 2 0 Chlorosome envelope protein C STN PF07660.14 ORY16816.1 - 0.098 12.5 0.5 13 5.7 0.1 2.9 2 0 0 2 2 2 0 Secretin and TonB N terminus short domain NEMO PF11577.8 ORY16816.1 - 0.51 10.4 2.7 8.1 6.5 0.7 3.1 3 0 0 3 3 3 0 NF-kappa-B essential modulator NEMO FlgN PF05130.12 ORY16816.1 - 1.9 9.0 4.3 8.8 6.8 0.6 3.5 3 1 0 3 3 3 0 FlgN protein Septin PF00735.18 ORY16818.1 - 8.6e-123 409.1 0.6 8.6e-123 409.1 0.6 1.7 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 ORY16818.1 - 7.8e-08 32.4 1.2 1.2e-07 31.8 0.0 2.0 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 ORY16818.1 - 2.6e-05 23.8 4.4 0.00071 19.2 0.0 3.2 2 2 0 2 2 2 1 Elongation factor Tu GTP binding domain AIG1 PF04548.16 ORY16818.1 - 0.00049 19.5 0.0 0.00049 19.5 0.0 2.4 2 0 0 2 2 2 1 AIG1 family ABC_tran PF00005.27 ORY16818.1 - 0.00092 19.7 5.5 0.019 15.5 0.0 2.7 2 1 0 2 2 2 1 ABC transporter RsgA_GTPase PF03193.16 ORY16818.1 - 0.0012 18.8 0.8 0.0012 18.8 0.8 3.6 3 1 0 3 3 3 1 RsgA GTPase AAA_16 PF13191.6 ORY16818.1 - 0.0014 19.1 0.1 0.0052 17.2 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain Roc PF08477.13 ORY16818.1 - 0.0027 17.9 0.0 0.0084 16.3 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 ORY16818.1 - 0.0028 17.2 0.0 0.012 15.2 0.0 2.1 1 0 0 1 1 1 1 Ras family AAA_22 PF13401.6 ORY16818.1 - 0.0038 17.5 1.0 0.017 15.4 0.0 2.6 2 2 0 2 2 2 1 AAA domain AAA_29 PF13555.6 ORY16818.1 - 0.013 15.3 0.0 0.024 14.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 ORY16818.1 - 0.013 15.0 0.0 0.027 14.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 ORY16818.1 - 0.019 14.7 0.0 0.048 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 ORY16818.1 - 0.035 14.5 2.2 0.53 10.7 0.0 2.7 3 0 0 3 3 2 0 RNA helicase FtsK_SpoIIIE PF01580.18 ORY16818.1 - 0.04 13.3 0.0 0.11 11.8 0.0 1.7 1 0 0 1 1 1 0 FtsK/SpoIIIE family Dynamin_N PF00350.23 ORY16818.1 - 0.31 11.1 11.8 0.86 9.6 0.1 3.8 2 2 1 3 3 3 0 Dynamin family Exonuc_VII_L PF02601.15 ORY16818.1 - 0.39 10.2 7.8 0.72 9.4 7.8 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit ATP_bind_1 PF03029.17 ORY16818.1 - 0.84 9.4 5.6 4.8 6.9 0.1 3.1 2 1 1 3 3 3 0 Conserved hypothetical ATP binding protein Atg14 PF10186.9 ORY16818.1 - 1.4 8.0 8.4 2.1 7.4 8.4 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF3987 PF13148.6 ORY16818.1 - 1.7 7.6 0.0 1.7 7.6 0.0 2.4 2 1 0 2 2 1 0 Protein of unknown function (DUF3987) DUF4085 PF13315.6 ORY16818.1 - 2.2 7.9 11.7 0.065 12.9 2.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF4085) DUF87 PF01935.17 ORY16818.1 - 7.3 6.6 8.4 4.8 7.2 0.0 2.8 3 0 0 3 3 3 0 Helicase HerA, central domain UPF0121 PF03661.13 ORY16819.1 - 1e-29 103.6 4.1 1.3e-29 103.3 4.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) Cyclin_N PF00134.23 ORY16821.1 - 0.033 13.9 0.0 0.12 12.1 0.0 1.9 1 1 0 1 1 1 0 Cyclin, N-terminal domain Phosphorylase PF00343.20 ORY16822.1 - 0 1065.7 0.0 0 1065.5 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase PhoU_div PF01865.16 ORY16822.1 - 0.12 11.7 0.0 3.5 6.9 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function DUF47 Yip1 PF04893.17 ORY16823.1 - 2.7e-13 50.0 14.2 5.2e-13 49.1 14.2 1.5 1 1 0 1 1 1 1 Yip1 domain YIF1 PF03878.15 ORY16823.1 - 0.022 14.3 3.6 0.052 13.0 3.1 1.9 1 1 0 1 1 1 0 YIF1 DSPc PF00782.20 ORY16825.1 - 5.2e-07 29.5 0.5 1.2e-06 28.3 0.4 1.8 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 ORY16825.1 - 0.0084 16.4 0.1 0.014 15.7 0.1 1.3 1 0 0 1 1 1 1 Rit1 DUSP-like domain Acetyltransf_10 PF13673.7 ORY16826.1 - 3.9e-11 43.0 0.0 8.2e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORY16826.1 - 6.6e-09 36.0 0.1 8.6e-08 32.4 0.1 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ORY16826.1 - 2.1e-08 34.5 0.1 9.2e-08 32.4 0.0 2.0 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain DUF1774 PF08611.10 ORY16827.1 - 6 7.3 11.5 1.8 9.0 0.9 2.8 2 1 1 3 3 3 0 Fungal protein of unknown function (DUF1774) AA_permease_2 PF13520.6 ORY16828.1 - 2e-51 175.2 46.9 2.5e-51 174.9 46.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ORY16828.1 - 9.8e-22 77.2 39.6 1.3e-21 76.7 39.6 1.0 1 0 0 1 1 1 1 Amino acid permease YlaH PF14036.6 ORY16828.1 - 0.18 12.1 3.5 0.5 10.7 0.4 3.1 2 0 0 2 2 2 0 YlaH-like protein HET PF06985.11 ORY16829.1 - 1.3e-27 97.0 0.2 2.5e-27 96.0 0.2 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Vpu PF00558.19 ORY16830.1 - 0.067 13.0 0.0 0.095 12.5 0.0 1.1 1 0 0 1 1 1 0 Vpu protein SfLAP PF11139.8 ORY16830.1 - 0.068 12.6 0.0 0.08 12.4 0.0 1.1 1 0 0 1 1 1 0 Sap, sulfolipid-1-addressing protein DUF4044 PF13253.6 ORY16832.1 - 0.31 10.6 1.7 0.75 9.4 1.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) BTB PF00651.31 ORY16833.1 - 2.5e-06 27.7 0.0 4.8e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Sec5 PF15469.6 ORY16834.1 - 1.2e-37 129.5 0.0 2.5e-37 128.6 0.0 1.5 1 0 0 1 1 1 1 Exocyst complex component Sec5 Vps51 PF08700.11 ORY16834.1 - 6.3e-05 23.0 0.1 0.00039 20.4 0.0 2.2 2 0 0 2 2 2 1 Vps51/Vps67 DUF2451 PF10474.9 ORY16835.1 - 0.0043 16.9 0.0 0.0093 15.8 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) DUF1996 PF09362.10 ORY16836.1 - 6.9e-78 261.9 2.5 8.2e-78 261.6 2.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) GATA-N PF05349.12 ORY16839.1 - 0.029 14.7 0.1 0.047 14.0 0.1 1.4 1 0 0 1 1 1 0 GATA-type transcription activator, N-terminal DUF4624 PF15417.6 ORY16869.1 - 0.0076 16.1 0.2 0.013 15.3 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4624) GFA PF04828.14 ORY16870.1 - 2.5e-23 82.2 0.4 3.7e-23 81.7 0.4 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Rpr2 PF04032.16 ORY16870.1 - 0.092 13.0 1.5 0.12 12.7 0.2 1.8 1 1 1 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain NOB1_Zn_bind PF08772.11 ORY16870.1 - 0.2 11.8 2.8 1.4 9.2 0.1 2.3 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like Ferric_reduct PF01794.19 ORY16871.1 - 5.2e-20 71.8 11.5 5.2e-20 71.8 11.5 2.8 3 0 0 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 ORY16871.1 - 0.0003 20.9 0.7 0.068 13.3 0.0 2.4 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 ORY16871.1 - 0.0004 20.4 0.0 0.00098 19.2 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain Importin_rep_4 PF18808.1 ORY16871.1 - 0.079 13.3 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 Importin repeat DUF326 PF03860.16 ORY16871.1 - 3 7.9 6.6 6.6 6.9 6.6 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF326) Ctr PF04145.15 ORY16872.1 - 8.2e-28 97.9 0.0 2.2e-27 96.5 0.0 1.6 1 1 0 1 1 1 1 Ctr copper transporter family Neprosin_AP PF14365.6 ORY16873.1 - 0.097 13.2 0.7 0.12 12.8 0.7 1.2 1 0 0 1 1 1 0 Neprosin activation peptide Lipase_GDSL_2 PF13472.6 ORY16874.1 - 0.018 15.4 0.0 0.025 15.0 0.0 1.5 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family ATG16 PF08614.11 ORY16875.1 - 8.3e-05 22.9 16.6 8.3e-05 22.9 16.6 6.0 3 1 3 6 6 6 2 Autophagy protein 16 (ATG16) Toxin_36 PF10550.9 ORY16875.1 - 3 9.4 7.5 20 6.9 0.2 4.6 3 0 0 3 3 3 0 Conantokin-G mollusc-toxin K_trans PF02705.16 ORY16876.1 - 2.2e-185 617.2 16.8 2.6e-185 617.0 16.8 1.0 1 0 0 1 1 1 1 K+ potassium transporter FAD_binding_4 PF01565.23 ORY16879.1 - 3.5e-22 78.7 0.2 7.1e-22 77.6 0.2 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 ORY16879.1 - 0.00016 21.7 0.0 0.00045 20.3 0.0 1.8 1 0 0 1 1 1 1 Berberine and berberine like MARVEL PF01284.23 ORY16880.1 - 1.8e-22 79.9 19.4 2.2e-22 79.7 19.4 1.1 1 0 0 1 1 1 1 Membrane-associating domain TNFR_16_TM PF18422.1 ORY16880.1 - 0.27 11.2 0.3 0.27 11.2 0.3 1.9 2 0 0 2 2 2 0 Tumor necrosis factor receptor member 16 trans-membrane domain DHHC PF01529.20 ORY16880.1 - 0.39 10.8 3.3 0.97 9.5 3.3 1.8 1 1 0 1 1 1 0 DHHC palmitoyltransferase CODH_A_N PF18537.1 ORY16884.1 - 0.15 12.1 0.0 0.25 11.4 0.0 1.3 1 0 0 1 1 1 0 Carbon monoxide dehydrogenase subunit alpha N-terminal domain CAP_N PF01213.19 ORY16885.1 - 3.8 6.9 4.1 4.8 6.6 4.1 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PAN_4 PF14295.6 ORY16886.1 - 0.0036 17.2 0.9 0.0065 16.3 0.9 1.4 1 0 0 1 1 1 1 PAN domain PAN_2 PF08276.11 ORY16886.1 - 0.021 15.0 0.3 0.041 14.0 0.3 1.4 1 0 0 1 1 1 0 PAN-like domain PAN_4 PF14295.6 ORY16887.1 - 6.8e-10 38.7 7.8 0.00015 21.6 2.1 2.5 2 0 0 2 2 2 2 PAN domain PAN_1 PF00024.26 ORY16887.1 - 2.7e-09 36.8 2.6 0.00019 21.4 0.8 2.5 2 0 0 2 2 2 2 PAN domain DUF4808 PF16066.5 ORY16887.1 - 0.068 13.7 0.0 0.37 11.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4808) MANEC PF07502.14 ORY16887.1 - 0.076 13.3 3.5 4.1 7.7 0.4 2.3 2 0 0 2 2 2 0 MANEC domain SKG6 PF08693.10 ORY16887.1 - 0.32 10.5 1.9 0.67 9.4 1.0 2.0 2 0 0 2 2 2 0 Transmembrane alpha-helix domain SLT PF01464.20 ORY16890.1 - 0.13 12.0 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Transglycosylase SLT domain Spc24 PF08286.11 ORY16891.1 - 0.13 12.5 2.9 0.13 12.5 0.6 1.9 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Uso1_p115_C PF04871.13 ORY16891.1 - 0.61 10.5 6.2 0.99 9.8 6.2 1.3 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region FliT PF05400.13 ORY16892.1 - 0.021 15.6 5.8 0.023 15.5 4.3 1.8 2 0 0 2 2 2 0 Flagellar protein FliT ADIP PF11559.8 ORY16892.1 - 0.024 14.7 0.4 0.034 14.2 0.4 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding ZapB PF06005.12 ORY16892.1 - 0.033 14.6 4.2 0.31 11.5 4.2 2.4 1 1 0 1 1 1 0 Cell division protein ZapB DivIC PF04977.15 ORY16892.1 - 0.035 13.9 2.7 0.035 13.9 2.7 2.2 2 1 1 3 3 3 0 Septum formation initiator LigT_PEase PF02834.16 ORY16892.1 - 0.057 13.6 0.4 0.32 11.2 0.1 2.2 1 1 2 3 3 3 0 LigT like Phosphoesterase TipAS PF07739.13 ORY16892.1 - 0.065 13.8 2.8 0.73 10.4 2.5 2.3 1 1 0 1 1 1 0 TipAS antibiotic-recognition domain Jnk-SapK_ap_N PF09744.9 ORY16892.1 - 0.097 12.9 3.8 0.096 12.9 3.2 1.4 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 MbeD_MobD PF04899.12 ORY16892.1 - 0.11 12.6 0.7 0.41 10.8 0.6 2.0 1 1 0 1 1 1 0 MbeD/MobD like DUF2220 PF09983.9 ORY16892.1 - 0.12 11.8 0.9 0.21 10.9 0.8 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria C-term(DUF2220) HALZ PF02183.18 ORY16892.1 - 1.6 9.0 7.6 1 9.7 1.4 3.0 3 1 1 4 4 4 0 Homeobox associated leucine zipper CHASE3 PF05227.13 ORY16893.1 - 0.0022 17.9 7.5 0.0022 17.9 7.5 2.0 1 1 0 1 1 1 1 CHASE3 domain RFC1 PF08519.12 ORY16893.1 - 0.0034 17.6 0.7 0.0049 17.0 0.7 1.2 1 0 0 1 1 1 1 Replication factor RFC1 C terminal domain OEP PF02321.18 ORY16893.1 - 0.22 11.3 9.9 0.11 12.3 5.6 2.0 1 1 1 2 2 2 0 Outer membrane efflux protein PEARLI-4 PF05278.12 ORY16893.1 - 0.3 10.6 18.9 0.84 9.2 10.1 2.0 1 1 1 2 2 2 0 Arabidopsis phospholipase-like protein (PEARLI 4) I_LWEQ PF01608.17 ORY16893.1 - 0.5 10.6 15.9 2 8.7 1.1 2.1 1 1 1 2 2 2 0 I/LWEQ domain COG2 PF06148.11 ORY16893.1 - 1.1 9.4 7.8 8 6.6 7.5 2.3 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Exonuc_VII_L PF02601.15 ORY16893.1 - 1.3 8.6 6.2 1.4 8.4 6.2 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF1664 PF07889.12 ORY16893.1 - 2.9 8.0 6.6 11 6.1 1.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Atg14 PF10186.9 ORY16893.1 - 3.1 6.8 8.4 3.7 6.5 8.4 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Csm1_N PF18504.1 ORY16893.1 - 9.5 6.6 14.1 1.6 9.1 6.1 2.6 2 1 0 2 2 2 0 Csm1 N-terminal domain DUF3584 PF12128.8 ORY16895.1 - 0.054 11.0 12.3 0.061 10.8 12.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Phosducin PF02114.16 ORY16895.1 - 0.24 10.3 6.9 0.29 10.1 6.9 1.2 1 0 0 1 1 1 0 Phosducin Myb_DNA-bind_7 PF15963.5 ORY16895.1 - 0.56 10.1 11.9 0.12 12.3 2.3 2.2 1 1 1 2 2 2 0 Myb DNA-binding like UPF0242 PF06785.11 ORY16895.1 - 7.5 6.6 14.0 9.8 6.2 14.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus LEA_1 PF03760.15 ORY16895.1 - 8.8 7.1 14.5 1.6 9.4 10.4 1.9 2 1 0 2 2 2 0 Late embryogenesis abundant (LEA) group 1 OmpH PF03938.14 ORY16896.1 - 0.026 14.9 1.6 0.042 14.2 1.6 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) TPR_MLP1_2 PF07926.12 ORY16896.1 - 0.028 14.5 0.9 0.051 13.6 0.9 1.3 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein FAM76 PF16046.5 ORY16896.1 - 0.078 12.3 0.4 0.11 11.8 0.4 1.1 1 0 0 1 1 1 0 FAM76 protein DHC_N1 PF08385.12 ORY16897.1 - 4.8e-127 425.0 3.3 4.8e-127 425.0 3.3 5.3 5 1 1 6 6 5 1 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.7 ORY16897.1 - 1.1e-124 415.7 1.1 9.2e-124 412.7 0.0 3.2 4 0 0 4 4 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 ORY16897.1 - 4e-116 388.4 8.4 4e-116 388.4 8.4 5.9 7 1 1 8 8 6 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 ORY16897.1 - 2.8e-73 245.7 1.1 2.8e-73 245.7 1.1 4.1 4 0 0 4 4 3 1 ATP-binding dynein motor region AAA_8 PF12780.7 ORY16897.1 - 1.1e-68 231.4 0.0 1.3e-67 227.9 0.0 2.8 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_7 PF12775.7 ORY16897.1 - 2.2e-41 141.4 0.0 1.9e-35 122.0 0.0 4.7 4 0 0 4 4 4 2 P-loop containing dynein motor region MT PF12777.7 ORY16897.1 - 1.8e-36 125.9 10.6 1.8e-36 125.9 10.6 3.4 4 0 0 4 4 3 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.14 ORY16897.1 - 1.4e-30 106.1 0.0 1.3e-11 44.7 0.0 5.6 4 1 0 4 4 4 4 AAA domain (dynein-related subfamily) Dynein_heavy PF03028.15 ORY16897.1 - 3.4e-30 104.6 0.1 1.1e-27 96.5 0.0 4.3 4 0 0 4 4 3 1 Dynein heavy chain region D6 P-loop domain AAA_lid_11 PF18198.1 ORY16897.1 - 1.3e-28 99.9 0.0 3.6e-28 98.4 0.0 1.9 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_AAA_lid PF17852.1 ORY16897.1 - 9.7e-18 64.5 1.2 3.1e-16 59.7 0.0 3.4 3 0 0 3 3 2 1 Dynein heavy chain AAA lid domain AAA_22 PF13401.6 ORY16897.1 - 1.7e-14 54.3 0.3 0.023 14.9 0.0 6.5 6 0 0 6 6 4 3 AAA domain AAA PF00004.29 ORY16897.1 - 2.6e-13 50.5 0.0 0.00085 19.7 0.0 4.9 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 ORY16897.1 - 2.5e-09 37.4 3.7 0.068 13.3 0.0 5.6 5 0 0 5 5 4 3 AAA domain AAA_18 PF13238.6 ORY16897.1 - 1.3e-08 35.5 3.6 0.093 13.3 0.0 5.9 5 0 0 5 5 5 2 AAA domain AAA_16 PF13191.6 ORY16897.1 - 8.5e-08 32.8 14.9 1.8 9.0 0.0 9.1 10 0 0 10 10 8 2 AAA ATPase domain T2SSE PF00437.20 ORY16897.1 - 1.9e-06 27.2 0.0 0.083 11.9 0.0 3.8 3 0 0 3 3 3 1 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.18 ORY16897.1 - 1.7e-05 24.3 2.7 0.23 10.8 0.1 4.3 4 0 0 4 4 4 2 FtsK/SpoIIIE family ABC_tran PF00005.27 ORY16897.1 - 1.9e-05 25.2 6.1 2.9 8.4 0.0 6.3 5 0 0 5 5 5 1 ABC transporter AAA_14 PF13173.6 ORY16897.1 - 2e-05 24.6 0.4 1.3 9.1 0.0 4.9 4 0 0 4 4 4 1 AAA domain AAA_lid_1 PF17857.1 ORY16897.1 - 2.3e-05 24.5 0.0 0.00073 19.7 0.0 3.6 3 0 0 3 3 2 1 AAA+ lid domain AAA_19 PF13245.6 ORY16897.1 - 4.6e-05 23.8 0.9 0.12 12.7 0.0 5.0 4 0 0 4 4 4 1 AAA domain AAA_29 PF13555.6 ORY16897.1 - 4.8e-05 23.0 0.3 2.3 8.1 0.0 3.6 3 0 0 3 3 3 2 P-loop containing region of AAA domain Mg_chelatase PF01078.21 ORY16897.1 - 0.00011 21.7 1.2 1.2 8.5 0.0 3.9 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 ORY16897.1 - 0.00014 21.6 5.2 21 4.8 0.0 6.7 6 0 0 6 6 6 0 AAA domain AAA_30 PF13604.6 ORY16897.1 - 0.0012 18.6 3.3 19 4.9 0.0 5.6 6 0 0 6 6 5 0 AAA domain AAA_25 PF13481.6 ORY16897.1 - 0.0013 18.3 0.0 0.097 12.2 0.0 3.5 3 0 0 3 3 3 1 AAA domain IstB_IS21 PF01695.17 ORY16897.1 - 0.0014 18.4 0.3 0.53 10.0 0.0 4.3 4 0 0 4 4 4 1 IstB-like ATP binding protein APG6_N PF17675.1 ORY16897.1 - 0.0026 18.3 2.4 0.0026 18.3 2.4 6.8 8 1 0 8 8 4 1 Apg6 coiled-coil region NTPase_1 PF03266.15 ORY16897.1 - 0.003 17.5 0.8 18 5.2 0.0 4.9 5 0 0 5 5 3 0 NTPase RNA_helicase PF00910.22 ORY16897.1 - 0.0043 17.4 0.2 22 5.5 0.0 4.6 4 0 0 4 4 4 0 RNA helicase OSCP PF00213.18 ORY16897.1 - 0.023 14.8 7.9 0.069 13.3 0.3 4.8 4 0 0 4 4 3 0 ATP synthase delta (OSCP) subunit Zeta_toxin PF06414.12 ORY16897.1 - 0.024 13.9 0.1 11 5.3 0.0 3.6 3 0 0 3 3 3 0 Zeta toxin Rad17 PF03215.15 ORY16897.1 - 0.052 13.5 3.0 2.6 7.9 0.0 4.1 5 0 0 5 5 4 0 Rad17 P-loop domain ResIII PF04851.15 ORY16897.1 - 0.1 12.6 0.8 8.6 6.3 0.0 4.1 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit NACHT PF05729.12 ORY16897.1 - 1.4 8.9 6.8 31 4.4 0.0 4.4 4 0 0 4 4 3 0 NACHT domain Voltage_CLC PF00654.20 ORY16898.1 - 6.1e-89 298.7 24.2 6.1e-89 298.7 24.2 1.4 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 ORY16898.1 - 1.1e-10 41.7 0.0 0.00018 21.8 0.0 2.5 2 0 0 2 2 2 2 CBS domain Peptidase_S10 PF00450.22 ORY16899.1 - 3.7e-97 326.4 0.0 4.7e-97 326.0 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase CBFD_NFYB_HMF PF00808.23 ORY16900.1 - 1e-11 44.9 0.4 1.4e-11 44.5 0.4 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 ORY16900.1 - 0.00026 21.3 0.3 0.00035 20.9 0.3 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Rieske PF00355.26 ORY16901.1 - 1.3e-10 41.1 0.0 2.5e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_TM PF02921.14 ORY16901.1 - 3e-10 40.4 0.3 7.1e-10 39.2 0.3 1.7 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Macro PF01661.21 ORY16902.1 - 9.9e-15 54.6 0.0 1.3e-14 54.3 0.0 1.2 1 0 0 1 1 1 1 Macro domain BCIP PF13862.6 ORY16903.1 - 1.9e-73 246.7 0.0 2.5e-73 246.3 0.0 1.2 1 0 0 1 1 1 1 p21-C-terminal region-binding protein GMP_synt_C PF00958.22 ORY16904.1 - 5.3e-43 145.0 0.0 1e-42 144.1 0.0 1.5 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.28 ORY16904.1 - 1.5e-41 142.3 0.0 2.3e-41 141.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NAD_synthase PF02540.17 ORY16904.1 - 3.7e-11 42.6 0.1 1.2e-06 27.8 0.1 2.2 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.13 ORY16904.1 - 1.5e-08 34.7 0.0 3.2e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 QueC PF06508.13 ORY16904.1 - 0.0017 17.9 0.0 0.0059 16.1 0.0 1.8 1 1 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 ORY16904.1 - 0.0032 16.3 0.1 0.0091 14.8 0.0 1.7 2 0 0 2 2 2 1 tRNA methyl transferase ThiI PF02568.14 ORY16904.1 - 0.006 16.2 0.0 0.018 14.7 0.0 1.7 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) Arginosuc_synth PF00764.19 ORY16904.1 - 0.021 14.2 0.1 0.035 13.4 0.1 1.3 1 0 0 1 1 1 0 Arginosuccinate synthase PAPS_reduct PF01507.19 ORY16904.1 - 0.058 13.4 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family ATP_bind_3 PF01171.20 ORY16904.1 - 0.13 12.0 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 PP-loop family adh_short PF00106.25 ORY16906.1 - 7.8e-52 175.6 0.0 1e-51 175.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY16906.1 - 1.7e-35 122.7 0.0 2.2e-35 122.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY16906.1 - 1.2e-10 41.6 0.0 1.7e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 ORY16906.1 - 0.02 15.1 0.1 0.039 14.2 0.1 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain THF_DHG_CYH_C PF02882.19 ORY16906.1 - 0.076 12.3 0.4 0.9 8.8 0.0 2.6 3 0 0 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF746 PF05344.11 ORY16907.1 - 0.1 12.4 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF746) Sipho_Gp157 PF05565.11 ORY16909.1 - 0.12 12.4 1.8 0.2 11.7 0.5 1.9 2 0 0 2 2 2 0 Siphovirus Gp157 EMP24_GP25L PF01105.24 ORY16910.1 - 1.7e-46 158.5 0.0 1.9e-46 158.3 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Myb_DNA-bind_6 PF13921.6 ORY16911.1 - 1.8e-05 24.9 1.8 4.7e-05 23.6 0.8 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain EspB PF05802.11 ORY16911.1 - 0.011 15.7 11.1 0.021 14.8 11.1 1.5 1 0 0 1 1 1 0 Enterobacterial EspB protein CBP4 PF07960.11 ORY16911.1 - 0.033 14.0 0.2 0.033 14.0 0.2 3.0 4 0 0 4 4 4 0 CBP4 Alpha-amylase PF00128.24 ORY16912.1 - 1.3e-111 373.4 0.1 2e-111 372.8 0.1 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.6 ORY16912.1 - 6.7e-05 22.2 0.0 0.00011 21.5 0.0 1.2 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain Malt_amylase_C PF16657.5 ORY16912.1 - 0.00027 21.0 0.0 0.00061 19.9 0.0 1.6 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain TMEM138 PF14935.6 ORY16913.1 - 0.056 14.1 1.5 0.071 13.8 0.2 1.7 2 0 0 2 2 2 0 Transmembrane protein 138 DUF5316 PF17247.2 ORY16913.1 - 0.071 13.1 4.3 0.39 10.8 0.2 2.8 2 1 0 2 2 2 0 Family of unknown function (DUF5316) DUF21 PF01595.20 ORY16913.1 - 0.11 12.2 0.1 0.2 11.4 0.1 1.4 1 0 0 1 1 1 0 Cyclin M transmembrane N-terminal domain DUF4386 PF14329.6 ORY16913.1 - 0.12 12.2 2.2 1.4 8.7 0.1 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4386) DUF1453 PF07301.11 ORY16913.1 - 0.9 9.5 5.0 3.1 7.8 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1453) DUF4131 PF13567.6 ORY16913.1 - 2 8.0 4.1 2.8 7.6 0.3 2.4 1 1 2 3 3 3 0 Domain of unknown function (DUF4131) PIG-Y PF15159.6 ORY16913.1 - 3.7 8.5 6.4 11 7.0 3.4 2.6 2 1 0 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y DUF2207 PF09972.9 ORY16913.1 - 5.5 5.6 5.1 21 3.7 4.8 1.9 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) MRJP PF03022.16 ORY16915.1 - 7.8e-19 68.1 0.1 1.3e-18 67.4 0.1 1.3 1 0 0 1 1 1 1 Major royal jelly protein NHL PF01436.21 ORY16915.1 - 0.0025 17.8 0.6 11 6.2 0.0 4.0 4 0 0 4 4 4 2 NHL repeat DUF3292 PF11696.8 ORY16916.1 - 0.0013 17.2 0.4 0.0036 15.8 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3292) Pyr_redox_3 PF13738.6 ORY16917.1 - 3e-16 59.5 0.0 3.2e-13 49.6 0.0 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ORY16917.1 - 3e-15 56.3 0.0 2.6e-12 46.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 ORY16917.1 - 2.3e-11 42.8 0.2 2.1e-08 33.0 0.1 2.4 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 ORY16917.1 - 8.4e-09 35.0 0.0 1.6e-05 24.2 0.0 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 ORY16917.1 - 0.00046 20.4 0.0 0.0065 16.7 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain 2-Hacid_dh_C PF02826.19 ORY16917.1 - 0.0075 15.6 0.0 0.053 12.9 0.0 2.0 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 ORY16917.1 - 0.033 14.3 0.0 3.2 7.8 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 ORY16917.1 - 0.14 12.5 0.0 0.61 10.4 0.0 2.0 2 0 0 2 2 2 0 TrkA-N domain Pyr_redox PF00070.27 ORY16917.1 - 0.14 12.8 0.0 16 6.1 0.0 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 ORY16917.1 - 0.14 11.4 0.0 0.33 10.2 0.0 1.6 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 ORY16917.1 - 0.14 10.8 0.1 0.79 8.4 0.0 1.9 2 0 0 2 2 2 0 HI0933-like protein GIDA PF01134.22 ORY16917.1 - 0.18 10.8 0.1 8.9 5.3 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A ADH_zinc_N_2 PF13602.6 ORY16918.1 - 1.4e-12 48.8 0.0 2.5e-12 48.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 ORY16918.1 - 1.9e-10 40.9 0.0 3.4e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ORY16918.1 - 4.7e-06 26.5 0.0 1.5e-05 24.8 0.0 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Coat_X PF07552.11 ORY16919.1 - 0.014 15.2 1.6 0.014 15.2 1.6 2.8 3 0 0 3 3 3 0 Spore Coat Protein X and V domain XPG_I_2 PF12813.7 ORY16919.1 - 0.11 12.0 0.1 0.17 11.3 0.1 1.3 1 0 0 1 1 1 0 XPG domain containing UDPGT PF00201.18 ORY16921.1 - 1.3e-10 40.7 0.0 1.8e-10 40.2 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 ORY16921.1 - 3.1e-05 24.0 0.0 5.2e-05 23.3 0.0 1.4 1 1 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Polysacc_deac_1 PF01522.21 ORY16922.1 - 0.038 13.9 0.0 0.45 10.4 0.0 2.3 1 1 1 2 2 2 0 Polysaccharide deacetylase adh_short PF00106.25 ORY16923.1 - 6.5e-09 35.5 2.9 2.4e-06 27.2 1.6 3.4 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY16923.1 - 0.0032 17.1 0.0 0.025 14.2 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase zf-MYND PF01753.18 ORY16924.1 - 6e-08 32.7 4.8 8.6e-08 32.1 4.8 1.3 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 ORY16924.1 - 0.0017 18.6 4.0 0.0026 18.0 4.0 1.3 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding Gamma-thionin PF00304.20 ORY16924.1 - 0.03 14.6 3.3 0.049 13.9 3.3 1.3 1 0 0 1 1 1 0 Gamma-thionin family zf-Mss51 PF13824.6 ORY16924.1 - 0.11 12.6 1.0 0.21 11.7 1.0 1.3 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 Ribonuc_L-PSP PF01042.21 ORY16925.1 - 1.1e-11 44.8 0.0 3.4e-11 43.2 0.0 1.7 1 1 0 1 1 1 1 Endoribonuclease L-PSP Pkinase PF00069.25 ORY16926.1 - 3.4e-35 121.7 0.0 5.5e-35 121.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY16926.1 - 4.9e-24 85.0 0.0 7.4e-24 84.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DUF1996 PF09362.10 ORY16927.1 - 3.9e-81 272.5 0.2 4.8e-81 272.2 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) MFS_1 PF07690.16 ORY16928.1 - 4.9e-38 131.0 31.3 4.9e-38 131.0 31.3 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Octopine_DH PF02317.17 ORY16929.1 - 2.3e-37 128.4 0.0 4.2e-37 127.5 0.0 1.4 1 0 0 1 1 1 1 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain NAD_Gly3P_dh_N PF01210.23 ORY16929.1 - 1.7e-09 37.9 0.0 2.8e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.16 ORY16929.1 - 6.6e-07 29.1 0.1 1.2e-06 28.2 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_8 PF13450.6 ORY16929.1 - 3.9e-05 23.8 0.2 8.6e-05 22.7 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain F420_oxidored PF03807.17 ORY16929.1 - 0.0013 19.2 0.0 0.0032 18.0 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Pyr_redox_2 PF07992.14 ORY16929.1 - 0.0017 17.6 0.0 0.0024 17.2 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ORY16929.1 - 0.0017 17.5 0.2 0.0026 16.9 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 ORY16929.1 - 0.0066 15.2 0.0 0.011 14.4 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein UDPG_MGDP_dh_N PF03721.14 ORY16929.1 - 0.012 15.2 0.0 0.024 14.2 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain GIDA PF01134.22 ORY16929.1 - 0.016 14.3 0.2 0.024 13.7 0.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A DAO PF01266.24 ORY16929.1 - 0.019 14.6 0.1 0.036 13.7 0.1 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 ORY16929.1 - 0.047 13.0 0.0 0.12 11.6 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_2 PF03446.15 ORY16929.1 - 0.047 13.9 0.0 0.079 13.1 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase PspC PF04024.12 ORY16929.1 - 0.068 13.0 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 PspC domain IlvN PF07991.12 ORY16929.1 - 0.076 12.6 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain PAGK PF15284.6 ORY16929.1 - 0.73 9.8 2.2 2.2 8.3 0.0 2.7 4 0 0 4 4 4 0 Phage-encoded virulence factor MFS_1 PF07690.16 ORY16930.1 - 5.9e-52 176.8 37.1 5.9e-52 176.8 37.1 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY16930.1 - 2.5e-16 59.6 27.4 3.5e-16 59.1 18.3 2.9 2 1 0 2 2 2 2 Sugar (and other) transporter Lysine_decarbox PF03641.14 ORY16930.1 - 0.03 14.4 0.0 0.057 13.5 0.0 1.4 1 0 0 1 1 1 0 Possible lysine decarboxylase OATP PF03137.20 ORY16930.1 - 0.39 8.9 18.6 0.0035 15.7 8.8 2.3 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family PsbI PF02532.14 ORY16930.1 - 0.71 9.9 4.0 36 4.4 0.0 3.1 2 0 0 2 2 2 0 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) Mobilization_B PF17511.2 ORY16930.1 - 1.8 8.9 3.9 1.6 9.1 0.1 2.2 2 0 0 2 2 2 0 Mobilization protein B Methyltransf_11 PF08241.12 ORY16931.1 - 7.7e-26 90.6 0.0 1.3e-25 89.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY16931.1 - 1.9e-24 86.2 0.0 3.4e-24 85.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY16931.1 - 2.3e-23 82.7 0.0 3e-23 82.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY16931.1 - 5.3e-18 65.6 0.0 1.3e-17 64.4 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY16931.1 - 2.7e-16 59.9 0.0 3.8e-16 59.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORY16931.1 - 5.3e-15 55.4 0.0 1e-14 54.5 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 ORY16931.1 - 2.8e-10 40.3 0.0 4.9e-10 39.5 0.0 1.4 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.12 ORY16931.1 - 2.6e-09 36.9 0.0 4.2e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.14 ORY16931.1 - 5.6e-09 35.8 0.0 8.7e-09 35.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 ORY16931.1 - 2.2e-08 33.7 0.0 2.9e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltr_RsmB-F PF01189.17 ORY16931.1 - 3.7e-07 30.0 0.0 8.1e-07 28.9 0.0 1.5 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltransf_24 PF13578.6 ORY16931.1 - 1.2e-05 26.3 0.0 3.3e-05 24.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.6 ORY16931.1 - 1.5e-05 25.0 0.0 8.7e-05 22.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_29 PF03141.16 ORY16931.1 - 4.8e-05 22.1 0.0 6.6e-05 21.6 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase NodS PF05401.11 ORY16931.1 - 0.00016 21.4 0.0 0.00023 20.9 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_4 PF02390.17 ORY16931.1 - 0.00021 20.8 0.0 0.00088 18.8 0.0 1.9 1 1 0 1 1 1 1 Putative methyltransferase RrnaAD PF00398.20 ORY16931.1 - 0.00031 19.9 0.0 0.00049 19.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_9 PF08003.11 ORY16931.1 - 0.00043 19.3 0.0 0.0008 18.4 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1698) PrmA PF06325.13 ORY16931.1 - 0.00054 19.4 0.0 0.0011 18.5 0.0 1.3 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Fibrillarin PF01269.17 ORY16931.1 - 0.0013 17.9 0.0 0.002 17.3 0.0 1.2 1 0 0 1 1 1 1 Fibrillarin FtsJ PF01728.19 ORY16931.1 - 0.0037 17.4 0.0 0.0057 16.8 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase ADH_zinc_N PF00107.26 ORY16931.1 - 0.0052 16.8 0.0 0.0099 15.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF3419 PF11899.8 ORY16931.1 - 0.0058 15.8 0.0 0.038 13.2 0.0 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF3419) TrkA_N PF02254.18 ORY16931.1 - 0.026 14.8 0.0 0.043 14.1 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain CheR PF01739.18 ORY16931.1 - 0.056 12.9 0.0 0.42 10.1 0.0 2.0 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain p450 PF00067.22 ORY16932.1 - 2.5e-73 247.4 0.0 3.8e-73 246.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_M26_C PF07580.14 ORY16932.1 - 0.053 12.0 0.0 0.073 11.6 0.0 1.1 1 0 0 1 1 1 0 M26 IgA1-specific Metallo-endopeptidase C-terminal region Elong-fact-P_C PF09285.11 ORY16932.1 - 0.072 12.8 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Elongation factor P, C-terminal MAPEG PF01124.18 ORY16932.1 - 0.12 12.3 1.8 0.49 10.3 0.4 2.3 2 0 0 2 2 2 0 MAPEG family HET PF06985.11 ORY16933.1 - 2.4e-32 112.3 0.3 7.9e-32 110.6 0.3 1.9 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF815 PF05673.13 ORY16933.1 - 0.0036 16.5 0.0 0.0057 15.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) DUF4184 PF13803.6 ORY16933.1 - 0.12 12.1 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4184) adh_short PF00106.25 ORY16934.1 - 5.1e-09 35.9 0.0 6.9e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY16934.1 - 2.8e-07 30.3 0.0 3.6e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase CUE PF02845.16 ORY16935.1 - 4.5e-11 42.2 0.0 8e-11 41.4 0.0 1.4 1 0 0 1 1 1 1 CUE domain HET PF06985.11 ORY16936.1 - 1.6e-11 44.8 0.0 3.2e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HET PF06985.11 ORY16939.1 - 7.2e-24 84.8 0.3 3.5e-23 82.6 0.3 2.0 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) HET PF06985.11 ORY16940.1 - 2.1e-33 115.7 1.3 3.9e-33 114.9 1.3 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HET PF06985.11 ORY16941.1 - 0.00042 20.7 0.2 0.0005 20.4 0.2 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HET PF06985.11 ORY16942.1 - 9.3e-21 74.7 1.9 1.1e-20 74.4 1.9 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PTR2 PF00854.21 ORY16943.1 - 1.2e-80 271.3 6.6 1.6e-80 270.9 6.6 1.1 1 0 0 1 1 1 1 POT family MFS_1 PF07690.16 ORY16943.1 - 2.5e-09 36.5 18.9 1.7e-08 33.8 17.3 2.4 1 1 1 2 2 2 1 Major Facilitator Superfamily Peptidase_S9 PF00326.21 ORY16945.1 - 5.1e-50 169.9 0.3 7.7e-50 169.3 0.3 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family PD40 PF07676.12 ORY16945.1 - 2.3e-05 24.2 0.6 0.53 10.3 0.1 3.5 2 1 0 2 2 2 2 WD40-like Beta Propeller Repeat COesterase PF00135.28 ORY16945.1 - 0.0033 16.3 0.1 0.0047 15.9 0.1 1.1 1 0 0 1 1 1 1 Carboxylesterase family DUF1295 PF06966.12 ORY16946.1 - 6.6e-34 117.5 0.1 8.8e-34 117.0 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.14 ORY16946.1 - 0.00045 20.6 0.0 0.00078 19.8 0.0 1.4 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Steroid_dh PF02544.16 ORY16946.1 - 0.0017 18.3 0.0 0.0034 17.4 0.0 1.5 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase ERG4_ERG24 PF01222.17 ORY16946.1 - 0.045 12.5 0.0 0.071 11.9 0.0 1.3 1 0 0 1 1 1 0 Ergosterol biosynthesis ERG4/ERG24 family BTB_2 PF02214.22 ORY16947.1 - 2.1e-11 44.0 0.0 5.5e-11 42.7 0.0 1.7 1 1 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 ORY16947.1 - 0.088 13.1 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 BTB/POZ domain BTB_2 PF02214.22 ORY16948.1 - 1.4e-07 31.8 0.0 3e-07 30.7 0.0 1.5 1 1 0 1 1 1 1 BTB/POZ domain NPDC1 PF06809.11 ORY16949.1 - 0.09 11.8 0.2 0.11 11.5 0.2 1.2 1 0 0 1 1 1 0 Neural proliferation differentiation control-1 protein (NPDC1) Arginase PF00491.21 ORY16950.1 - 4e-83 279.2 0.3 4.8e-83 278.9 0.3 1.0 1 0 0 1 1 1 1 Arginase family Cyt-b5 PF00173.28 ORY16951.1 - 6.7e-05 23.0 0.0 7.5e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Cathelicidins PF00666.17 ORY16952.1 - 0.029 14.7 0.6 0.031 14.6 0.6 1.0 1 0 0 1 1 1 0 Cathelicidin RRM_1 PF00076.22 ORY16953.1 - 1e-57 191.8 0.0 3.2e-17 62.1 0.0 5.4 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 ORY16953.1 - 7.2e-05 23.1 0.3 30 4.8 0.0 5.7 4 3 2 6 6 6 0 Cytosolic domain of 10TM putative phosphate transporter RRM_5 PF13893.6 ORY16953.1 - 0.00013 21.5 0.0 0.46 10.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 ORY16953.1 - 0.0037 17.3 0.3 0.8 9.8 0.0 4.2 4 0 0 4 4 4 1 Limkain b1 RRM_occluded PF16842.5 ORY16953.1 - 0.0095 15.8 0.0 2.6 8.0 0.0 3.1 3 0 0 3 3 3 1 Occluded RNA-recognition motif DbpA PF03880.15 ORY16953.1 - 0.05 13.6 0.1 4.9 7.2 0.0 2.8 2 0 0 2 2 2 0 DbpA RNA binding domain RRM_7 PF16367.5 ORY16953.1 - 0.068 13.3 0.0 22 5.3 0.0 3.7 4 0 0 4 4 4 0 RNA recognition motif DUF5471 PF17565.2 ORY16953.1 - 0.25 11.7 1.6 3.8 7.8 0.1 3.1 3 0 0 3 3 3 0 Family of unknown function (DUF5471) Malt_amylase_C PF16657.5 ORY16954.1 - 2.8e-06 27.3 0.0 4.6e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain Alpha-amylase_C PF02806.18 ORY16954.1 - 0.011 16.1 0.0 0.02 15.3 0.0 1.5 1 0 0 1 1 1 0 Alpha amylase, C-terminal all-beta domain MFS_1 PF07690.16 ORY16955.1 - 3.1e-27 95.4 24.0 4.4e-27 94.9 24.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Ribosomal_L6 PF00347.23 ORY16955.1 - 4.7e-24 84.9 5.3 5.3e-12 46.2 1.2 2.3 2 0 0 2 2 2 2 Ribosomal protein L6 Sugar_tr PF00083.24 ORY16955.1 - 1.8e-20 73.2 12.2 7.8e-20 71.2 12.2 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter Aldo_ket_red PF00248.21 ORY16956.1 - 2.7e-67 227.0 0.0 3.3e-67 226.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Pkinase PF00069.25 ORY16959.1 - 1.3e-21 77.1 0.0 2e-21 76.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY16959.1 - 9.3e-10 38.2 0.0 1.3e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 ORY16959.1 - 0.00097 18.6 0.0 0.0021 17.4 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 ORY16959.1 - 0.037 12.8 0.0 0.057 12.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase DUF3382 PF11862.8 ORY16962.1 - 0.041 14.2 0.1 0.05 13.9 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3382) Glyco_hydro_67M PF07488.12 ORY16965.1 - 2.1e-145 483.9 0.1 3.7e-145 483.0 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 middle domain Glyco_hydro_67C PF07477.12 ORY16965.1 - 4.8e-86 287.9 2.3 7.4e-86 287.3 2.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 C-terminus Glyco_hydro_67N PF03648.14 ORY16965.1 - 1.3e-30 106.2 0.0 2.6e-30 105.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 N-terminus Glyco_hydro_20b PF02838.15 ORY16965.1 - 7.8e-05 23.4 0.1 0.00028 21.7 0.1 1.9 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 DUF4838 PF16126.5 ORY16965.1 - 0.034 13.5 0.1 0.12 11.7 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4838) Ank_2 PF12796.7 ORY16966.1 - 9.7e-09 35.7 0.0 3.5e-08 33.9 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY16966.1 - 9.3e-07 29.3 0.0 2.6e-05 24.7 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 ORY16966.1 - 8.7e-06 26.0 0.2 0.98 10.0 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 ORY16966.1 - 0.00089 19.5 0.2 0.073 13.4 0.0 3.2 3 1 1 4 4 4 2 Ankyrin repeats (many copies) FTH PF01827.27 ORY16967.1 - 0.067 13.0 0.1 0.12 12.2 0.1 1.3 1 0 0 1 1 1 0 FTH domain DUF1272 PF06906.11 ORY16967.1 - 0.087 12.9 4.1 0.2 11.7 4.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) DUF2310 PF10071.9 ORY16967.1 - 0.99 8.6 4.1 2.1 7.6 4.1 1.5 1 0 0 1 1 1 0 Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310) HET PF06985.11 ORY16973.1 - 3.3e-07 30.8 0.0 6.5e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Nodulin PF02451.15 ORY16975.1 - 0.032 13.7 0.7 0.05 13.1 0.7 1.3 1 0 0 1 1 1 0 Nodulin DUF3328 PF11807.8 ORY16977.1 - 1.9e-42 145.5 0.2 2.4e-42 145.2 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) PBP1_TM PF14812.6 ORY16979.1 - 0.074 13.4 4.7 0.33 11.4 4.7 2.1 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-B_dimeris PF09026.10 ORY16979.1 - 0.21 12.0 5.8 0.6 10.5 5.8 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain RRN3 PF05327.11 ORY16979.1 - 3.4 6.1 4.8 5.3 5.5 4.8 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Nop14 PF04147.12 ORY16979.1 - 4.6 5.3 15.0 0.35 9.0 8.7 1.9 2 0 0 2 2 2 0 Nop14-like family Ca_chan_IQ PF08763.11 ORY16980.1 - 0.011 16.0 0.0 0.023 14.9 0.0 1.5 1 0 0 1 1 1 0 Voltage gated calcium channel IQ domain Amidohydro_2 PF04909.14 ORY16981.1 - 4.2e-32 112.1 0.0 6.5e-32 111.5 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase Cys_Met_Meta_PP PF01053.20 ORY16982.1 - 2e-37 128.6 0.0 2.7e-37 128.2 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 ORY16982.1 - 2.4e-09 36.9 0.0 3.5e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II AMP-binding PF00501.28 ORY16983.1 - 2.7e-73 247.0 0.0 3.6e-73 246.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 ORY16983.1 - 3.5e-12 46.5 0.1 7.8e-12 45.4 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.6 ORY16983.1 - 0.00014 22.7 0.1 0.00043 21.2 0.1 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Condensation PF00668.20 ORY16983.1 - 0.00068 18.4 0.0 0.0019 17.0 0.0 1.6 1 1 0 1 1 1 1 Condensation domain ABC_membrane PF00664.23 ORY16984.1 - 3e-105 351.8 35.0 1.4e-54 185.6 14.4 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 ORY16984.1 - 1.3e-67 226.5 0.2 5.9e-33 114.3 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 ORY16984.1 - 7e-15 55.1 4.9 0.00018 21.0 0.0 4.3 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 ORY16984.1 - 1.6e-08 35.1 3.1 0.0085 16.5 0.1 3.3 2 1 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 ORY16984.1 - 7.9e-08 32.4 0.1 0.015 15.2 0.0 2.8 3 0 0 3 3 2 2 RsgA GTPase AAA_22 PF13401.6 ORY16984.1 - 2e-07 31.4 2.0 0.0014 18.9 0.1 4.1 3 2 0 3 3 3 2 AAA domain ABC_ATPase PF09818.9 ORY16984.1 - 4e-07 29.2 1.2 0.014 14.2 0.1 2.4 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_29 PF13555.6 ORY16984.1 - 9.1e-07 28.5 0.0 0.015 15.0 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.6 ORY16984.1 - 9.6e-06 25.5 0.3 0.057 13.1 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_5 PF07728.14 ORY16984.1 - 0.00012 22.1 0.8 0.31 11.1 0.0 3.7 4 0 0 4 4 3 1 AAA domain (dynein-related subfamily) AAA_23 PF13476.6 ORY16984.1 - 0.00038 21.0 0.0 1.2 9.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain Rad17 PF03215.15 ORY16984.1 - 0.00047 20.1 0.1 0.051 13.5 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain G-alpha PF00503.20 ORY16984.1 - 0.00061 19.1 0.0 0.39 9.8 0.0 2.4 2 0 0 2 2 2 2 G-protein alpha subunit AAA_21 PF13304.6 ORY16984.1 - 0.0007 19.5 4.3 1.2 8.9 0.1 3.9 5 0 0 5 5 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_7 PF12775.7 ORY16984.1 - 0.00095 18.7 0.0 0.66 9.5 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_28 PF13521.6 ORY16984.1 - 0.0013 19.0 0.1 0.92 9.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 ORY16984.1 - 0.0015 18.2 3.0 0.58 9.9 0.0 3.5 3 2 0 3 3 2 1 AAA domain AAA_18 PF13238.6 ORY16984.1 - 0.0019 18.8 0.2 0.42 11.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain ATP-synt_ab PF00006.25 ORY16984.1 - 0.0037 16.9 4.5 1.5 8.4 0.2 3.6 3 2 0 3 3 3 2 ATP synthase alpha/beta family, nucleotide-binding domain PRK PF00485.18 ORY16984.1 - 0.0037 17.0 0.1 1 9.1 0.0 2.7 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family DUF815 PF05673.13 ORY16984.1 - 0.0067 15.6 0.0 1.5 7.9 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA PF00004.29 ORY16984.1 - 0.0081 16.6 4.1 14 6.2 1.3 4.2 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 ORY16984.1 - 0.013 15.0 0.0 7.4 6.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 ORY16984.1 - 0.014 14.7 0.0 4 6.7 0.0 2.7 2 0 0 2 2 2 0 Zeta toxin RNA_helicase PF00910.22 ORY16984.1 - 0.014 15.7 0.5 3.1 8.2 0.0 3.2 3 0 0 3 3 2 0 RNA helicase AAA_24 PF13479.6 ORY16984.1 - 0.027 14.2 0.2 0.76 9.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 ORY16984.1 - 0.043 13.8 0.0 2.3 8.3 0.0 3.1 3 1 0 3 3 2 0 AAA domain Synapsin_N PF10581.9 ORY16984.1 - 0.044 13.7 0.0 5.1 7.1 0.0 2.5 2 0 0 2 2 2 0 Synapsin N-terminal Mg_chelatase PF01078.21 ORY16984.1 - 0.045 13.1 0.0 0.66 9.3 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI SbcCD_C PF13558.6 ORY16984.1 - 0.057 13.6 7.2 4.2 7.7 0.3 4.5 3 2 0 3 3 2 0 Putative exonuclease SbcCD, C subunit DUF87 PF01935.17 ORY16984.1 - 0.076 13.1 0.0 14 5.7 0.0 2.7 2 0 0 2 2 2 0 Helicase HerA, central domain TniB PF05621.11 ORY16984.1 - 0.083 12.3 0.1 11 5.3 0.0 3.2 4 0 0 4 4 4 0 Bacterial TniB protein AAA_33 PF13671.6 ORY16984.1 - 0.089 13.0 0.1 2.8 8.1 0.0 2.8 3 0 0 3 3 2 0 AAA domain IstB_IS21 PF01695.17 ORY16984.1 - 0.1 12.3 3.4 0.56 9.9 0.0 3.4 5 0 0 5 5 3 0 IstB-like ATP binding protein MMR_HSR1 PF01926.23 ORY16984.1 - 0.16 12.1 4.0 8.3 6.5 0.1 3.3 4 0 0 4 4 2 0 50S ribosome-binding GTPase ATPgrasp_N PF18130.1 ORY16985.1 - 6.2e-16 58.7 0.0 1.3e-15 57.7 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp N-terminal domain ATP-grasp_4 PF13535.6 ORY16985.1 - 2.3e-09 37.0 0.0 6.3e-09 35.6 0.0 1.8 1 1 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 ORY16985.1 - 0.0011 18.5 0.0 0.0022 17.6 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 ORY16985.1 - 0.0051 16.9 0.0 0.062 13.4 0.0 2.2 2 0 0 2 2 2 1 ATP-grasp domain ketoacyl-synt PF00109.26 ORY16986.1 - 7.5e-76 255.0 2.0 2.1e-75 253.6 1.3 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 ORY16986.1 - 1.6e-34 118.5 0.2 3.7e-34 117.2 0.2 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.21 ORY16986.1 - 1.3e-18 67.6 0.0 2.3e-18 66.8 0.0 1.2 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 ORY16986.1 - 1.5e-15 57.3 0.0 3.2e-15 56.2 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase SAT PF16073.5 ORY16986.1 - 9.3e-15 55.0 1.5 3.4e-13 49.9 0.2 2.7 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Abhydrolase_3 PF07859.13 ORY16986.1 - 9.5e-13 48.5 0.0 1.2e-10 41.7 0.0 2.4 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 ORY16986.1 - 1.6e-09 37.5 0.0 2.2e-06 27.3 0.0 2.4 2 0 0 2 2 2 2 Prolyl oligopeptidase family PP-binding PF00550.25 ORY16986.1 - 2.9e-08 33.9 1.0 7.5e-08 32.6 1.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.23 ORY16986.1 - 2.3e-07 30.4 0.8 4.5e-07 29.5 0.8 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain KAsynt_C_assoc PF16197.5 ORY16986.1 - 1.5e-05 25.4 0.0 3.9e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Abhydrolase_6 PF12697.7 ORY16986.1 - 2e-05 25.3 1.5 4.7e-05 24.1 0.8 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family DLH PF01738.18 ORY16986.1 - 0.00025 20.6 0.0 0.016 14.7 0.0 2.4 2 0 0 2 2 2 1 Dienelactone hydrolase family LIP PF03583.14 ORY16986.1 - 0.00096 18.6 0.0 0.0024 17.2 0.0 1.6 1 0 0 1 1 1 1 Secretory lipase Hydrolase_4 PF12146.8 ORY16986.1 - 0.0091 15.3 0.0 0.051 12.8 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 ORY16986.1 - 0.04 13.5 0.0 0.33 10.5 0.0 2.1 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.20 ORY16986.1 - 0.064 12.9 1.7 0.23 11.1 0.0 2.6 3 0 0 3 3 3 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 ORY16986.1 - 0.089 12.6 0.0 1.5 8.6 0.0 2.5 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase FSH1 PF03959.13 ORY16986.1 - 0.091 12.4 0.0 1.8 8.2 0.0 2.4 2 0 0 2 2 2 0 Serine hydrolase (FSH1) MFS_1 PF07690.16 ORY16987.1 - 5.4e-06 25.6 2.8 6.3e-06 25.3 2.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY16987.1 - 3.4e-05 22.9 2.2 0.0002 20.3 0.2 1.9 1 1 0 2 2 2 2 Sugar (and other) transporter DUF4407 PF14362.6 ORY16987.1 - 0.041 13.2 0.7 0.059 12.7 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) MFS_1 PF07690.16 ORY16988.1 - 1e-22 80.6 29.5 2.1e-22 79.6 29.5 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF2721 PF11026.8 ORY16988.1 - 1.1 9.2 10.4 0.91 9.4 1.8 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF2721) YoqO PF14037.6 ORY16988.1 - 1.6 9.3 7.3 0.27 11.8 3.3 1.7 2 0 0 2 2 2 0 YoqO-like protein adh_short_C2 PF13561.6 ORY16989.1 - 2e-55 187.9 3.0 3.1e-55 187.3 3.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY16989.1 - 1.9e-39 135.2 0.9 3.5e-39 134.3 0.9 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORY16989.1 - 5.3e-07 29.7 0.9 8.9e-07 29.0 0.3 1.6 2 0 0 2 2 2 1 KR domain NAD_binding_7 PF13241.6 ORY16989.1 - 0.02 15.3 0.1 0.062 13.7 0.1 1.9 2 0 0 2 2 2 0 Putative NAD(P)-binding ThiF PF00899.21 ORY16989.1 - 0.085 12.2 0.5 0.42 9.9 0.5 1.9 2 1 0 2 2 2 0 ThiF family NusB PF01029.18 ORY16989.1 - 0.14 12.4 0.0 0.24 11.6 0.0 1.3 1 0 0 1 1 1 0 NusB family Spherulin4 PF12138.8 ORY16990.1 - 2.3e-111 371.2 0.1 6.7e-56 189.6 0.1 2.0 1 1 1 2 2 2 2 Spherulation-specific family 4 F-box PF00646.33 ORY16991.1 - 0.00031 20.5 0.3 0.00031 20.5 0.3 1.9 2 0 0 2 2 2 1 F-box domain F-box_4 PF15966.5 ORY16991.1 - 0.011 15.6 0.2 0.022 14.6 0.2 1.5 1 0 0 1 1 1 0 F-box F-box-like PF12937.7 ORY16991.1 - 0.051 13.5 0.2 0.11 12.5 0.2 1.6 1 0 0 1 1 1 0 F-box-like DAO PF01266.24 ORY16993.1 - 6.9e-44 150.9 0.5 8.2e-44 150.6 0.5 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 ORY16993.1 - 0.0033 16.7 0.0 0.0076 15.5 0.0 1.5 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 ORY16993.1 - 0.0036 17.5 0.2 0.012 15.8 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 ORY16993.1 - 0.035 13.4 0.0 1 8.5 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ORY16993.1 - 0.038 13.1 0.1 0.6 9.1 0.0 2.4 3 0 0 3 3 3 0 FAD binding domain Pyr_redox_2 PF07992.14 ORY16993.1 - 0.05 12.8 0.0 0.12 11.6 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ORY16993.1 - 0.11 12.4 0.2 0.23 11.5 0.2 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding 2-Hacid_dh_C PF02826.19 ORY16995.1 - 2.1e-45 154.3 0.0 3.5e-45 153.5 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 ORY16995.1 - 3.7e-26 91.4 0.0 4.3e-26 91.1 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain F420_oxidored PF03807.17 ORY16995.1 - 0.0088 16.6 0.0 0.029 14.9 0.0 2.0 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Fungal_trans PF04082.18 ORY16996.1 - 4.5e-09 35.7 0.1 7e-08 31.8 0.2 2.3 2 1 0 2 2 2 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 ORY16996.1 - 5.8e-08 32.8 11.2 0.00011 22.5 0.1 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY16996.1 - 3.2e-07 30.5 0.7 3.2e-07 30.5 0.7 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORY16996.1 - 3.3e-07 30.6 10.0 0.0024 18.6 0.1 3.0 3 0 0 3 3 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 ORY16996.1 - 0.00052 19.9 5.7 0.0048 16.9 0.0 2.7 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2HC_2 PF13913.6 ORY16996.1 - 0.00056 19.7 6.1 0.021 14.7 0.2 2.6 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.8 ORY16996.1 - 0.0025 18.1 6.1 1.5 9.2 0.0 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 ORY16996.1 - 0.0059 16.3 0.1 0.0059 16.3 0.1 2.5 2 0 0 2 2 2 1 zinc-finger C2H2-type BolA PF01722.18 ORY16996.1 - 0.079 13.3 0.7 11 6.4 0.3 2.6 1 1 1 2 2 2 0 BolA-like protein CxC5 PF18718.1 ORY16996.1 - 0.11 12.6 0.4 0.25 11.5 0.4 1.5 1 0 0 1 1 1 0 CxC5 like cysteine cluster associated with KDZ transposases PHD PF00628.29 ORY16996.1 - 0.25 11.2 3.5 0.57 10.1 3.5 1.6 1 0 0 1 1 1 0 PHD-finger Zf_RING PF16744.5 ORY16996.1 - 4.6 7.4 6.7 26 5.0 0.1 2.9 2 1 1 3 3 2 0 KIAA1045 RING finger zf-met PF12874.7 ORY16996.1 - 9.2 6.8 9.5 4.3 7.9 0.1 3.0 3 0 0 3 3 3 0 Zinc-finger of C2H2 type MFS_1 PF07690.16 ORY16997.1 - 3.5e-32 111.7 47.6 7.7e-30 104.0 24.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily p450 PF00067.22 ORY16998.1 - 1e-15 57.5 0.2 1.9e-15 56.6 0.2 1.4 1 0 0 1 1 1 1 Cytochrome P450 3-dmu-9_3-mt PF06983.13 ORY17000.1 - 2.3e-44 150.7 0.0 2.9e-44 150.3 0.0 1.1 1 0 0 1 1 1 1 3-demethylubiquinone-9 3-methyltransferase zf-RING_UBOX PF13445.6 ORY17002.1 - 0.00048 20.1 1.3 0.00048 20.1 1.3 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 ORY17002.1 - 0.002 18.5 9.8 0.0042 17.4 9.8 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 ORY17002.1 - 0.69 9.8 8.2 1.7 8.5 8.2 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 ORY17002.1 - 0.76 9.7 10.1 0.59 10.0 8.1 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) ADH_N PF08240.12 ORY17003.1 - 6.8e-11 42.0 0.8 3.3e-10 39.8 0.2 2.3 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORY17003.1 - 1.7e-09 37.7 0.1 3.1e-09 36.9 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 ORY17003.1 - 0.042 13.7 0.0 0.088 12.7 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase SIR2 PF02146.17 ORY17004.1 - 9.2e-38 129.9 0.0 1.6e-37 129.2 0.0 1.4 1 1 0 1 1 1 1 Sir2 family zf-ribbon_3 PF13248.6 ORY17004.1 - 0.37 10.3 0.1 0.37 10.3 0.1 2.0 2 0 0 2 2 2 0 zinc-ribbon domain FAM184 PF15665.5 ORY17006.1 - 0.00049 19.9 20.9 0.00049 19.9 20.9 2.2 2 1 2 4 4 4 2 Family with sequence similarity 184, A and B SOAR PF16533.5 ORY17006.1 - 0.00072 19.5 3.9 0.00072 19.5 3.9 2.6 1 1 1 2 2 2 1 STIM1 Orai1-activating region P22_AR_C PF10548.9 ORY17006.1 - 0.026 14.7 0.0 0.079 13.1 0.0 1.8 1 0 0 1 1 1 0 P22AR C-terminal domain V_ATPase_I PF01496.19 ORY17006.1 - 0.048 11.6 7.5 0.062 11.2 7.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spc7 PF08317.11 ORY17006.1 - 5.2 5.9 20.8 10 4.9 20.8 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein GvpL_GvpF PF06386.11 ORY17006.1 - 6.1 6.7 9.6 0.46 10.4 3.7 2.0 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF Baculo_PEP_C PF04513.12 ORY17006.1 - 7.7 6.6 8.3 38 4.3 2.0 3.1 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus LysE PF01810.18 ORY17007.1 - 0.093 12.2 4.8 1.3 8.4 0.2 2.2 1 1 1 2 2 2 0 LysE type translocator NanE PF04131.14 ORY17007.1 - 0.11 11.7 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase PARP PF00644.20 ORY17008.1 - 6.1e-09 35.8 0.1 1.1e-08 34.9 0.1 1.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain SATase_N PF06426.14 ORY17009.1 - 0.12 12.7 2.6 2 8.8 0.0 3.5 4 0 0 4 4 4 0 Serine acetyltransferase, N-terminal Nre_C PF04895.12 ORY17009.1 - 0.86 9.5 3.1 4.3 7.3 0.1 2.9 3 0 0 3 3 3 0 Archaeal Nre, C-terminal Ank_2 PF12796.7 ORY17010.1 - 6e-09 36.4 0.0 7.1e-07 29.7 0.1 2.9 1 1 2 3 3 3 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ORY17010.1 - 8.4e-08 32.3 1.1 0.00025 21.3 0.1 3.8 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 ORY17010.1 - 1e-07 32.4 0.0 0.072 13.7 0.0 3.4 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY17010.1 - 5e-07 29.5 0.3 0.028 14.9 0.1 4.3 4 0 0 4 4 4 1 Ankyrin repeat Ank PF00023.30 ORY17010.1 - 8.6e-05 22.8 5.0 0.0016 18.8 0.2 3.7 3 1 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 ORY17011.1 - 1.6e-26 92.3 2.2 2.5e-12 47.1 0.2 2.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 ORY17011.1 - 2.6e-25 88.8 2.3 6.5e-12 45.9 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ORY17011.1 - 8.4e-22 74.9 3.9 0.00027 21.2 0.0 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 ORY17011.1 - 1.2e-18 67.0 3.9 2e-07 31.2 0.6 3.9 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 ORY17011.1 - 1.7e-16 59.8 4.2 0.0018 18.7 0.0 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.6 ORY17012.1 - 5.3e-18 65.2 2.2 1.7e-07 31.7 0.1 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 ORY17012.1 - 7.6e-15 55.3 0.1 1.9e-08 34.8 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ORY17012.1 - 5.6e-13 47.8 0.3 0.023 15.2 0.0 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 ORY17012.1 - 1.3e-11 44.5 0.3 2.5e-07 30.8 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 ORY17012.1 - 1e-08 35.2 0.7 0.068 13.6 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeat NACHT PF05729.12 ORY17013.1 - 0.079 12.9 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 NACHT domain DSPc PF00782.20 ORY17014.1 - 1.3e-21 76.8 0.0 2.4e-18 66.2 0.0 2.1 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 ORY17014.1 - 0.012 15.3 0.0 0.016 14.8 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase PhoD PF09423.10 ORY17015.1 - 2.6e-06 26.7 0.1 0.00072 18.7 0.1 2.5 2 1 0 2 2 2 2 PhoD-like phosphatase Ifi-6-16 PF06140.13 ORY17016.1 - 4.5e-12 45.7 0.1 7.2e-12 45.1 0.1 1.3 1 0 0 1 1 1 1 Interferon-induced 6-16 family AA_permease_2 PF13520.6 ORY17017.1 - 1.6e-54 185.4 38.8 2e-54 185.0 38.8 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ORY17017.1 - 1.6e-26 93.0 37.3 2.6e-26 92.3 34.6 2.1 1 1 0 1 1 1 1 Amino acid permease DPPIV_N PF00930.21 ORY17018.1 - 1.3e-110 369.5 8.3 1.8e-110 369.1 8.3 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 ORY17018.1 - 4.6e-39 134.1 0.4 8.4e-39 133.2 0.4 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 ORY17018.1 - 0.00044 20.0 0.4 0.0017 18.1 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 ORY17018.1 - 0.00075 19.2 0.0 0.0014 18.3 0.0 1.5 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.7 ORY17018.1 - 0.012 16.2 0.0 0.029 15.0 0.0 1.7 1 0 0 1 1 1 0 Alpha/beta hydrolase family PD40 PF07676.12 ORY17018.1 - 0.028 14.4 0.1 0.35 10.8 0.0 2.9 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat DUF2920 PF11144.8 ORY17018.1 - 0.08 12.1 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) HSP70 PF00012.20 ORY17048.1 - 5.5e-15 54.6 0.0 7.8e-15 54.1 0.0 1.1 1 0 0 1 1 1 1 Hsp70 protein ZapB PF06005.12 ORY17049.1 - 0.00013 22.4 1.4 0.0003 21.2 1.4 1.5 1 0 0 1 1 1 1 Cell division protein ZapB APG6_N PF17675.1 ORY17049.1 - 0.00039 20.9 2.6 0.00077 20.0 2.6 1.5 1 0 0 1 1 1 1 Apg6 coiled-coil region TSC22 PF01166.18 ORY17049.1 - 0.0032 17.7 1.6 0.0071 16.6 1.6 1.6 1 0 0 1 1 1 1 TSC-22/dip/bun family ADIP PF11559.8 ORY17049.1 - 0.0041 17.2 4.8 0.0078 16.3 1.7 2.2 2 0 0 2 2 2 1 Afadin- and alpha -actinin-Binding GAS PF13851.6 ORY17049.1 - 0.0047 16.3 2.1 0.008 15.5 2.1 1.4 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Hemagglutinin PF00509.18 ORY17049.1 - 0.01 14.3 0.1 0.014 13.8 0.1 1.1 1 0 0 1 1 1 0 Haemagglutinin EzrA PF06160.12 ORY17049.1 - 0.011 14.0 2.2 0.015 13.5 2.2 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA AAA_13 PF13166.6 ORY17049.1 - 0.02 13.6 0.2 0.027 13.1 0.2 1.1 1 0 0 1 1 1 0 AAA domain Herpes_UL6 PF01763.16 ORY17049.1 - 0.022 13.3 0.2 0.03 12.9 0.2 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like PhaP_Bmeg PF09602.10 ORY17049.1 - 0.035 14.0 0.7 0.08 12.9 0.7 1.6 1 0 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) Snapin_Pallidin PF14712.6 ORY17049.1 - 0.038 14.4 0.4 0.079 13.4 0.4 1.5 1 0 0 1 1 1 0 Snapin/Pallidin TMF_TATA_bd PF12325.8 ORY17049.1 - 0.044 14.0 0.8 0.11 12.7 0.8 1.6 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding ANAPC4 PF12896.7 ORY17049.1 - 0.068 12.7 0.3 0.13 11.7 0.3 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 4 GIT_CC PF16559.5 ORY17049.1 - 0.076 12.9 1.2 0.12 12.2 0.5 1.7 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF4735 PF15882.5 ORY17049.1 - 0.079 12.4 0.5 0.12 11.8 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4735) GrpE PF01025.19 ORY17049.1 - 0.09 12.4 2.1 0.17 11.5 1.5 1.7 2 0 0 2 2 2 0 GrpE CENP-F_leu_zip PF10473.9 ORY17049.1 - 0.35 10.9 7.4 0.032 14.3 2.2 1.8 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SpoU_methylase PF00588.19 ORY17050.1 - 1.2e-22 80.6 0.0 2e-22 79.9 0.0 1.4 1 0 0 1 1 1 1 SpoU rRNA Methylase family Kinesin PF00225.23 ORY17051.1 - 2.8e-111 371.7 0.0 4.3e-111 371.0 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 ORY17051.1 - 8.1e-27 94.0 0.1 2.4e-26 92.5 0.0 1.8 2 0 0 2 2 2 1 Microtubule binding Lebercilin PF15619.6 ORY17051.1 - 0.015 15.0 11.1 0.51 10.0 5.9 2.4 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DUF5567 PF17722.1 ORY17051.1 - 0.03 14.2 2.1 0.069 13.0 2.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5567) GAS PF13851.6 ORY17051.1 - 0.066 12.5 10.4 0.11 11.8 10.4 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 ORY17051.1 - 0.067 12.1 10.7 0.11 11.4 10.7 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein YabA PF06156.13 ORY17051.1 - 0.24 12.0 13.7 0.14 12.8 1.5 3.8 2 1 1 3 3 3 0 Initiation control protein YabA DUF3573 PF12097.8 ORY17051.1 - 0.38 9.5 1.3 0.58 8.9 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) DUF87 PF01935.17 ORY17051.1 - 0.71 9.9 4.7 0.76 9.8 0.0 2.6 2 1 0 2 2 2 0 Helicase HerA, central domain ZapB PF06005.12 ORY17051.1 - 1.5 9.3 15.6 0.41 11.1 7.5 2.6 1 1 1 2 2 2 0 Cell division protein ZapB MRP-S26 PF14943.6 ORY17051.1 - 1.9 8.4 10.2 4.1 7.3 10.2 1.5 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 PRKG1_interact PF15898.5 ORY17051.1 - 5.2 8.0 16.5 0.82 10.6 11.2 2.4 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain bZIP_2 PF07716.15 ORY17051.1 - 6.7 6.9 12.8 0.33 11.1 0.2 3.1 1 1 1 2 2 2 0 Basic region leucine zipper Vps16_N PF04841.13 ORY17052.1 - 4.8e-97 325.3 0.0 7e-97 324.8 0.0 1.2 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.12 ORY17052.1 - 4.3e-86 288.9 0.0 6.2e-86 288.4 0.0 1.2 1 0 0 1 1 1 1 Vps16, C-terminal region ANAPC4_WD40 PF12894.7 ORY17052.1 - 5.1e-05 23.5 0.0 0.17 12.2 0.0 2.8 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain GTP_EFTU PF00009.27 ORY17053.1 - 1.3e-56 191.2 0.2 1.7e-56 190.9 0.2 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 ORY17053.1 - 2.3e-26 92.3 0.0 4.8e-26 91.3 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 ORY17053.1 - 2e-16 60.1 1.6 2e-16 60.1 1.6 1.8 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 ORY17053.1 - 9.9e-05 22.4 0.0 0.00019 21.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ORY17053.1 - 0.00078 19.4 0.0 0.0024 17.8 0.0 1.8 2 0 0 2 2 2 1 RsgA GTPase cobW PF02492.19 ORY17053.1 - 0.0043 16.7 0.6 0.062 12.9 0.1 2.1 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 ORY17053.1 - 0.05 13.3 0.6 6.9 6.4 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ECH_2 PF16113.5 ORY17054.1 - 6.4e-125 417.1 0.0 7.8e-125 416.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 ORY17054.1 - 1e-28 100.4 0.0 2.7e-28 99.0 0.0 1.6 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase DIRP PF06584.13 ORY17055.1 - 0.091 12.9 0.2 0.2 11.9 0.2 1.5 1 0 0 1 1 1 0 DIRP TipE PF16972.5 ORY17055.1 - 3.9 6.6 5.9 0.63 9.2 1.7 1.7 2 0 0 2 2 2 0 Na+ channel auxiliary subunit TipE Kinesin PF00225.23 ORY17056.1 - 1.8e-57 194.8 0.0 3e-57 194.0 0.0 1.3 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 ORY17056.1 - 1.3e-11 44.7 0.0 2.4e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 Microtubule binding MFS_1 PF07690.16 ORY17057.1 - 1e-32 113.5 45.1 1.4e-32 113.0 42.2 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 ORY17057.1 - 7.6e-07 27.9 19.6 1.6e-06 26.9 19.6 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) TPIP1 PF15338.6 ORY17057.1 - 0.095 12.8 2.5 0.098 12.7 0.9 1.8 2 0 0 2 2 2 0 p53-regulated apoptosis-inducing protein 1 Carn_acyltransf PF00755.20 ORY17058.1 - 1.4e-95 321.1 0.1 2e-95 320.7 0.1 1.2 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase ketoacyl-synt PF00109.26 ORY17058.1 - 2.9e-70 236.8 0.0 4.9e-70 236.0 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 ORY17058.1 - 3.4e-55 186.7 0.4 7.5e-55 185.6 0.4 1.6 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 ORY17058.1 - 4.9e-51 173.7 0.0 9.4e-51 172.8 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 ORY17058.1 - 2.9e-50 171.6 0.1 4.8e-50 170.9 0.1 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 ORY17058.1 - 9.4e-38 128.9 0.2 2.4e-37 127.5 0.2 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 ORY17058.1 - 3.2e-17 63.0 1.3 2.4e-11 44.1 0.0 2.8 2 0 0 2 2 2 2 Ketoacyl-synthetase C-terminal extension ADH_zinc_N_2 PF13602.6 ORY17058.1 - 4.5e-15 56.9 0.0 1e-13 52.4 0.0 3.2 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 ORY17058.1 - 9.4e-13 48.3 0.0 5.3e-12 45.8 0.0 2.4 2 0 0 2 2 1 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.12 ORY17058.1 - 2.9e-10 40.8 0.0 9.7e-10 39.1 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 ORY17058.1 - 1.8e-09 37.3 1.8 3.5e-09 36.4 0.2 2.2 2 0 0 2 2 2 1 short chain dehydrogenase Methyltransf_31 PF13847.6 ORY17058.1 - 4e-09 36.4 0.0 2.2e-08 34.0 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain PP-binding PF00550.25 ORY17058.1 - 4.4e-09 36.5 0.3 8.5e-08 32.4 0.1 2.8 2 0 0 2 2 2 1 Phosphopantetheine attachment site adh_short_C2 PF13561.6 ORY17058.1 - 7.4e-09 35.5 0.3 1.7e-08 34.3 0.3 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Methyltransf_25 PF13649.6 ORY17058.1 - 2.6e-07 31.3 0.0 1e-05 26.1 0.0 3.0 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORY17058.1 - 4.9e-06 26.0 0.0 3.1e-05 23.4 0.0 2.3 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 ORY17058.1 - 1.9e-05 24.5 0.0 7e-05 22.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY17058.1 - 3.6e-05 24.3 0.0 0.00012 22.6 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 ORY17058.1 - 0.00029 20.6 0.1 0.22 11.2 0.0 2.5 2 0 0 2 2 2 2 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) ADH_N PF08240.12 ORY17058.1 - 0.0067 16.3 0.0 0.02 14.7 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain NAD_binding_10 PF13460.6 ORY17058.1 - 0.016 15.1 0.1 0.045 13.7 0.1 1.8 1 0 0 1 1 1 0 NAD(P)H-binding Methyltransf_16 PF10294.9 ORY17058.1 - 0.079 12.7 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase Thiolase_N PF00108.23 ORY17058.1 - 0.087 12.2 0.1 0.24 10.8 0.1 1.7 1 0 0 1 1 1 0 Thiolase, N-terminal domain Glyco_hydro_4 PF02056.16 ORY17058.1 - 0.099 12.2 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Family 4 glycosyl hydrolase 2-Hacid_dh_C PF02826.19 ORY17058.1 - 0.14 11.5 0.3 0.5 9.7 0.0 2.0 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Collagen PF01391.18 ORY17058.1 - 0.16 11.8 9.7 0.26 11.0 6.5 2.3 1 1 1 2 2 2 0 Collagen triple helix repeat (20 copies) RTA1 PF04479.13 ORY17059.1 - 1.4e-69 233.9 4.9 1.8e-69 233.5 4.9 1.1 1 0 0 1 1 1 1 RTA1 like protein NADH-u_ox-rdase PF10785.9 ORY17059.1 - 0.0038 17.9 2.3 6.2 7.6 0.8 3.3 2 1 0 2 2 2 2 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit GFO_IDH_MocA PF01408.22 ORY17060.1 - 4e-17 63.1 0.0 7.5e-17 62.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA PF01408.22 ORY17061.1 - 1.4e-20 74.3 0.4 3.4e-20 73.1 0.4 1.7 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 ORY17061.1 - 0.019 15.6 0.2 0.034 14.8 0.2 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Cys_rich_CPCC PF14206.6 ORY17062.1 - 0.07 13.0 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Cysteine-rich CPCC TFIIA PF03153.13 ORY17063.1 - 3.3 7.6 17.1 4.3 7.2 17.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit F-box PF00646.33 ORY17064.1 - 0.0051 16.7 0.0 0.017 15.0 0.0 1.9 1 1 0 1 1 1 1 F-box domain LRR_4 PF12799.7 ORY17064.1 - 0.1 13.1 0.2 8.2 7.0 0.0 3.6 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) Ank_2 PF12796.7 ORY17067.1 - 0.0018 18.8 0.1 0.063 13.9 0.0 1.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 ORY17067.1 - 0.0084 16.5 0.1 0.083 13.4 0.1 2.4 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 ORY17067.1 - 0.066 13.8 0.1 0.8 10.5 0.0 2.5 2 0 0 2 2 2 0 Ankyrin repeat Ank_4 PF13637.6 ORY17067.1 - 0.16 12.6 0.3 2.1 9.1 0.0 2.5 2 0 0 2 2 2 0 Ankyrin repeats (many copies) NAD_binding_8 PF13450.6 ORY17068.1 - 3e-10 40.2 0.0 6.9e-08 32.6 0.0 2.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.19 ORY17068.1 - 4.6e-10 38.5 7.3 1.8e-07 30.0 0.3 3.5 2 2 1 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 ORY17068.1 - 1.8e-09 37.3 0.6 0.00066 19.0 0.1 3.1 3 0 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 ORY17068.1 - 0.00014 21.9 0.0 0.014 15.5 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.6 ORY17068.1 - 0.00048 20.2 0.0 2 8.4 0.0 3.2 3 0 0 3 3 3 1 FAD-NAD(P)-binding HI0933_like PF03486.14 ORY17068.1 - 0.0005 18.9 0.3 0.041 12.6 0.0 2.4 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 ORY17068.1 - 0.00053 19.3 0.1 0.0022 17.3 0.0 1.8 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 ORY17068.1 - 0.00063 19.4 0.9 0.048 13.2 0.1 2.8 2 1 1 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 ORY17068.1 - 0.00073 20.0 0.5 1.4 9.5 0.2 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ORY17068.1 - 0.0013 17.9 0.5 0.0028 16.8 0.1 1.6 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 ORY17068.1 - 0.015 14.6 0.3 3.2 6.9 0.0 3.0 2 1 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ORY17068.1 - 0.021 14.0 0.0 0.24 10.5 0.0 2.3 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 ORY17068.1 - 0.048 12.9 0.4 0.43 9.8 0.1 2.0 2 0 0 2 2 2 0 FAD binding domain Beta-lactamase PF00144.24 ORY17069.1 - 3.3e-42 144.9 0.0 1e-41 143.3 0.0 1.6 1 1 0 1 1 1 1 Beta-lactamase XPG_I PF00867.18 ORY17070.1 - 3e-25 88.4 0.0 6.4e-25 87.3 0.0 1.6 1 0 0 1 1 1 1 XPG I-region Zn_clus PF00172.18 ORY17070.1 - 3.7e-06 26.9 6.4 1.8e-05 24.8 6.4 2.3 1 1 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain XPG_N PF00752.17 ORY17070.1 - 0.028 14.9 0.0 0.068 13.7 0.0 1.6 1 0 0 1 1 1 0 XPG N-terminal domain Catalase PF00199.19 ORY17073.1 - 8.3e-177 588.0 0.0 9.9e-177 587.8 0.0 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 ORY17073.1 - 2.1e-14 53.5 0.0 5.6e-14 52.1 0.0 1.8 1 0 0 1 1 1 1 Catalase-related immune-responsive DUF587 PF04532.12 ORY17074.1 - 0.027 13.7 1.2 0.027 13.7 1.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF587) GxDLY PF14607.6 ORY17074.1 - 0.12 12.2 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 N-terminus of Esterase_SGNH_hydro-type p450 PF00067.22 ORY17075.1 - 2e-41 142.2 0.0 2.7e-41 141.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 ORY17076.1 - 1e-38 133.2 50.8 1e-38 133.2 50.8 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 ORY17076.1 - 5.9e-13 48.1 14.3 5.9e-13 48.1 14.3 2.2 1 1 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) DUF4730 PF15873.5 ORY17076.1 - 0.14 12.5 0.3 0.14 12.5 0.3 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4730) TetR_N PF00440.23 ORY17076.1 - 0.56 10.1 2.9 0.46 10.3 0.3 2.2 2 0 0 2 2 2 0 Bacterial regulatory proteins, tetR family DCP2 PF05026.13 ORY17077.1 - 1.4e-30 105.4 1.3 2.5e-30 104.6 1.3 1.4 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.28 ORY17077.1 - 3.3e-16 59.5 0.0 6.5e-16 58.6 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain DUF4112 PF13430.6 ORY17078.1 - 2.7e-28 98.3 0.3 3.5e-28 97.9 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) HOOK PF05622.12 ORY17080.1 - 0.0026 16.0 29.9 0.0037 15.5 29.9 1.1 1 0 0 1 1 1 1 HOOK protein DUF4200 PF13863.6 ORY17080.1 - 0.0064 16.9 19.9 0.0064 16.9 19.9 3.3 1 1 1 3 3 3 2 Domain of unknown function (DUF4200) Helo_like_N PF17111.5 ORY17080.1 - 0.015 14.7 16.2 0.018 14.4 0.2 3.5 3 0 0 3 3 3 0 Fungal N-terminal domain of STAND proteins PKcGMP_CC PF16808.5 ORY17080.1 - 0.17 11.8 12.0 3 7.8 3.3 3.2 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase BLOC1_2 PF10046.9 ORY17080.1 - 0.26 11.6 26.7 0.88 9.9 10.4 3.3 3 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF812 PF05667.11 ORY17080.1 - 0.33 9.8 35.1 2.3 7.0 14.5 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF812) DUF3584 PF12128.8 ORY17080.1 - 0.97 6.9 29.9 1.4 6.4 29.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) ATG16 PF08614.11 ORY17080.1 - 1.4 9.1 33.6 1.3 9.2 10.4 2.8 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) IFT57 PF10498.9 ORY17080.1 - 1.5 7.7 29.4 6.6 5.6 15.2 2.4 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 Seryl_tRNA_N PF02403.22 ORY17080.1 - 2 8.7 31.4 2.8 8.2 16.0 3.8 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF641 PF04859.12 ORY17080.1 - 3.6 7.9 25.4 0.13 12.6 11.2 3.3 2 1 1 3 3 3 0 Plant protein of unknown function (DUF641) Mod_r PF07200.13 ORY17080.1 - 4.3 7.4 32.1 15 5.6 12.6 3.1 2 1 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein TMF_TATA_bd PF12325.8 ORY17080.1 - 5.6 7.2 34.1 0.96 9.7 13.0 3.0 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding Fez1 PF06818.15 ORY17080.1 - 5.9 7.3 33.8 5.2 7.5 12.6 2.4 1 1 1 2 2 2 0 Fez1 CENP-H PF05837.12 ORY17080.1 - 5.9 7.3 26.2 11 6.4 10.8 2.7 2 0 0 2 2 2 0 Centromere protein H (CENP-H) CAP_N PF01213.19 ORY17081.1 - 0.073 12.5 0.0 0.15 11.5 0.1 1.5 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal CTU2 PF10288.9 ORY17082.1 - 8.1e-15 55.0 0.1 1.5e-12 47.7 0.0 2.6 2 0 0 2 2 2 2 Cytoplasmic tRNA 2-thiolation protein 2 RsdA_SigD_bd PF16751.5 ORY17082.1 - 0.063 13.6 0.2 0.18 12.1 0.2 1.7 1 0 0 1 1 1 0 Anti-sigma-D factor RsdA to sigma factor binding region ATP_bind_3 PF01171.20 ORY17082.1 - 0.17 11.6 0.0 13 5.5 0.1 2.2 2 0 0 2 2 2 0 PP-loop family Lung_7-TM_R PF06814.13 ORY17083.1 - 1.2e-67 228.3 19.3 1.6e-67 227.8 19.3 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor AAA PF00004.29 ORY17086.1 - 8.1e-98 324.0 0.0 1.5e-47 161.3 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 ORY17086.1 - 1.3e-23 82.5 2.2 2e-12 46.7 0.2 3.0 2 1 0 2 2 2 2 AAA+ lid domain CDC48_N PF02359.18 ORY17086.1 - 1.1e-18 67.2 1.0 2.8e-18 65.9 0.4 2.1 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_2 PF07724.14 ORY17086.1 - 3.7e-14 53.2 0.0 1.5e-07 31.7 0.0 2.9 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 ORY17086.1 - 1.5e-13 50.8 0.0 1.2e-05 25.1 0.0 3.3 4 1 0 4 4 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 ORY17086.1 - 2e-12 47.8 0.0 0.00011 22.6 0.0 4.4 2 2 0 2 2 2 2 AAA ATPase domain AAA_33 PF13671.6 ORY17086.1 - 3.1e-12 46.9 0.0 1.6e-05 25.1 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_5 PF07728.14 ORY17086.1 - 1.3e-10 41.4 0.5 2e-05 24.6 0.1 3.8 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) TIP49 PF06068.13 ORY17086.1 - 3.2e-09 36.4 0.1 0.0015 17.9 0.0 2.7 2 1 0 2 2 2 2 TIP49 P-loop domain AAA_22 PF13401.6 ORY17086.1 - 6.5e-09 36.2 0.5 0.05 13.9 0.0 4.2 2 2 1 3 3 3 2 AAA domain CDC48_2 PF02933.17 ORY17086.1 - 2.2e-07 30.6 0.1 4.9e-07 29.4 0.1 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 ATPase PF06745.13 ORY17086.1 - 3.9e-07 29.6 0.2 0.15 11.4 0.0 3.4 3 0 0 3 3 3 2 KaiC Mg_chelatase PF01078.21 ORY17086.1 - 4.5e-07 29.4 0.3 0.038 13.4 0.1 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 ORY17086.1 - 5.6e-07 29.9 0.0 0.025 15.0 0.0 2.8 2 0 0 2 2 2 2 RNA helicase IstB_IS21 PF01695.17 ORY17086.1 - 8.5e-07 28.9 0.0 0.037 13.8 0.0 2.9 2 0 0 2 2 2 2 IstB-like ATP binding protein Vps4_C PF09336.10 ORY17086.1 - 1.3e-06 28.3 0.1 1.4e-05 25.0 0.0 2.4 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_18 PF13238.6 ORY17086.1 - 1.3e-06 28.9 0.5 0.058 13.9 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_14 PF13173.6 ORY17086.1 - 2e-06 27.8 0.0 0.015 15.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 ORY17086.1 - 6.2e-06 25.8 0.0 0.047 13.2 0.0 3.1 2 2 0 2 2 2 2 P-loop containing dynein motor region AAA_25 PF13481.6 ORY17086.1 - 1.2e-05 25.0 3.9 0.8 9.3 0.1 4.7 3 2 1 5 5 5 1 AAA domain AAA_24 PF13479.6 ORY17086.1 - 1.7e-05 24.6 0.0 0.13 12.0 0.0 2.9 3 0 0 3 3 2 2 AAA domain Parvo_NS1 PF01057.17 ORY17086.1 - 3e-05 23.2 0.1 0.1 11.6 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 DUF815 PF05673.13 ORY17086.1 - 3.8e-05 23.0 0.0 0.029 13.5 0.0 2.8 3 0 0 3 3 2 1 Protein of unknown function (DUF815) AAA_28 PF13521.6 ORY17086.1 - 5.7e-05 23.4 0.0 0.47 10.7 0.0 2.9 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.26 ORY17086.1 - 6e-05 22.8 0.0 0.46 10.2 0.0 3.3 2 2 0 2 2 2 2 Sigma-54 interaction domain ABC_tran PF00005.27 ORY17086.1 - 0.00011 22.7 0.0 0.32 11.5 0.0 3.4 2 1 0 2 2 2 1 ABC transporter PhoH PF02562.16 ORY17086.1 - 0.00019 20.9 0.4 0.47 9.9 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein AAA_17 PF13207.6 ORY17086.1 - 0.0002 21.8 0.1 0.59 10.6 0.0 3.4 3 0 0 3 3 2 1 AAA domain Bac_DnaA PF00308.18 ORY17086.1 - 0.0002 21.3 0.0 0.5 10.2 0.0 2.9 3 0 0 3 3 2 2 Bacterial dnaA protein AAA_11 PF13086.6 ORY17086.1 - 0.00029 20.7 0.3 1.1 9.0 0.1 2.8 2 1 0 2 2 2 2 AAA domain TsaE PF02367.17 ORY17086.1 - 0.00032 20.7 0.0 1.1 9.2 0.0 2.8 2 1 1 3 3 3 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_3 PF07726.11 ORY17086.1 - 0.00044 20.1 0.0 1.1 9.1 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ResIII PF04851.15 ORY17086.1 - 0.00048 20.2 0.0 0.074 13.1 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF2075 PF09848.9 ORY17086.1 - 0.00096 18.5 0.0 1.2 8.3 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) ATPase_2 PF01637.18 ORY17086.1 - 0.0012 18.8 0.0 2.5 7.9 0.0 3.7 3 1 0 3 3 3 1 ATPase domain predominantly from Archaea NACHT PF05729.12 ORY17086.1 - 0.0022 18.0 0.1 1.4 8.8 0.0 2.9 3 0 0 3 3 3 1 NACHT domain AAA_30 PF13604.6 ORY17086.1 - 0.0027 17.4 0.4 2.4 7.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 ORY17086.1 - 0.0083 15.3 0.0 2.1 7.4 0.0 2.8 3 0 0 3 3 2 1 NB-ARC domain Viral_helicase1 PF01443.18 ORY17086.1 - 0.0094 15.7 0.0 0.67 9.6 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase Zeta_toxin PF06414.12 ORY17086.1 - 0.011 15.0 0.0 6 6.1 0.0 2.8 2 0 0 2 2 2 0 Zeta toxin AAA_19 PF13245.6 ORY17086.1 - 0.011 16.0 1.1 9.6 6.5 0.0 3.4 3 1 0 4 4 2 0 AAA domain KAP_NTPase PF07693.14 ORY17086.1 - 0.025 13.8 0.4 0.97 8.6 0.0 2.8 2 2 1 3 3 3 0 KAP family P-loop domain Sigma54_activ_2 PF14532.6 ORY17086.1 - 0.025 14.7 0.0 4 7.5 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain IPT PF01745.16 ORY17086.1 - 0.03 13.7 0.0 2.4 7.5 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase NTPase_1 PF03266.15 ORY17086.1 - 0.036 14.0 0.4 6.8 6.6 0.0 3.6 3 0 0 3 3 3 0 NTPase Zot PF05707.12 ORY17086.1 - 0.037 13.7 0.0 2.4 7.7 0.0 3.2 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) UFD1 PF03152.14 ORY17086.1 - 0.047 13.2 0.0 0.41 10.1 0.0 2.1 1 1 1 2 2 2 0 Ubiquitin fusion degradation protein UFD1 AAA_6 PF12774.7 ORY17086.1 - 0.088 11.8 0.0 9 5.1 0.0 2.4 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region EnY2 PF10163.9 ORY17087.1 - 0.0068 16.7 0.0 0.0085 16.4 0.0 1.2 1 0 0 1 1 1 1 Transcription factor e(y)2 SAM_2 PF07647.17 ORY17088.1 - 3e-14 52.8 0.0 5.1e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 ORY17088.1 - 1.5e-13 51.0 0.0 2.3e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.23 ORY17088.1 - 2.3e-13 50.6 0.3 7.7e-13 48.9 0.0 1.9 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain YabA PF06156.13 ORY17088.1 - 0.0052 17.4 0.1 0.0098 16.5 0.1 1.4 1 0 0 1 1 1 1 Initiation control protein YabA DUF1840 PF08895.11 ORY17088.1 - 0.33 11.3 1.8 0.73 10.2 1.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) Pkinase PF00069.25 ORY17090.1 - 5.7e-05 22.6 0.0 0.00026 20.4 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY17090.1 - 0.0014 18.0 0.0 0.17 11.1 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase zf-Di19 PF05605.12 ORY17090.1 - 1.1 9.7 10.7 4.6 7.6 0.3 3.5 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding FAD_binding_3 PF01494.19 ORY17091.1 - 2e-78 264.1 0.0 2.3e-76 257.3 0.0 2.1 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 ORY17091.1 - 1.5e-42 145.5 0.0 2.5e-42 144.7 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain DAO PF01266.24 ORY17091.1 - 1.5e-07 31.3 0.1 0.00096 18.8 0.0 2.5 1 1 1 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ORY17091.1 - 0.00099 19.3 0.0 0.0025 18.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ORY17091.1 - 0.0017 17.7 0.0 0.0039 16.5 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 ORY17091.1 - 0.0074 15.5 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 Thi4 family SE PF08491.10 ORY17091.1 - 0.0086 15.2 0.0 0.64 9.0 0.0 2.1 2 0 0 2 2 2 1 Squalene epoxidase Pyr_redox PF00070.27 ORY17091.1 - 0.015 15.9 0.0 0.046 14.3 0.0 1.9 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ORY17091.1 - 0.026 13.6 0.0 0.062 12.4 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_3 PF13738.6 ORY17091.1 - 0.052 12.8 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase XG_FTase PF03254.13 ORY17091.1 - 0.094 11.3 0.0 0.14 10.8 0.0 1.1 1 0 0 1 1 1 0 Xyloglucan fucosyltransferase Trp_halogenase PF04820.14 ORY17091.1 - 0.18 10.6 0.0 0.29 10.0 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase PIG-F PF06699.11 ORY17092.1 - 1.2e-65 221.1 5.5 1.3e-65 220.9 5.5 1.0 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F Gly-zipper_Omp PF13488.6 ORY17092.1 - 0.0054 16.7 2.6 0.027 14.5 2.6 2.0 1 1 0 1 1 1 1 Glycine zipper DUF4396 PF14342.6 ORY17092.1 - 0.016 15.5 0.8 0.37 11.1 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4396) Gly-zipper_YMGG PF13441.6 ORY17092.1 - 0.023 14.4 2.0 0.17 11.7 1.9 2.1 1 1 0 1 1 1 0 YMGG-like Gly-zipper Gly-zipper_OmpA PF13436.6 ORY17092.1 - 0.29 11.0 3.6 14 5.6 0.1 2.4 2 0 0 2 2 2 0 Glycine-zipper domain ABC2_membrane_2 PF12679.7 ORY17092.1 - 0.74 9.0 5.1 1.4 8.1 5.1 1.4 1 0 0 1 1 1 0 ABC-2 family transporter protein Acetyltransf_1 PF00583.25 ORY17093.1 - 5.8e-05 23.3 0.0 0.00011 22.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ORY17093.1 - 0.00089 19.6 0.0 0.0018 18.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ORY17093.1 - 0.0015 18.4 0.0 0.0025 17.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 ORY17093.1 - 0.0037 17.2 0.3 0.01 15.8 0.1 1.8 1 1 1 2 2 2 1 ESCO1/2 acetyl-transferase PanZ PF12568.8 ORY17093.1 - 0.017 14.8 0.0 0.028 14.2 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ Translin PF01997.16 ORY17094.1 - 3e-44 151.5 0.0 3.5e-44 151.2 0.0 1.0 1 0 0 1 1 1 1 Translin family DUF2868 PF11067.8 ORY17094.1 - 0.0054 16.3 0.1 0.0075 15.8 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2868) Chs7 PF12271.8 ORY17096.1 - 3.5e-125 417.1 19.9 4e-125 416.9 19.9 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone DUF4281 PF14108.6 ORY17096.1 - 0.0049 17.2 4.0 0.0049 17.2 4.0 2.2 3 0 0 3 3 3 1 Domain of unknown function (DUF4281) DUF3382 PF11862.8 ORY17096.1 - 0.098 12.9 0.3 0.098 12.9 0.3 2.5 2 1 0 3 3 3 0 Domain of unknown function (DUF3382) Dak1 PF02733.17 ORY17097.1 - 7.1e-100 333.9 0.0 1e-99 333.4 0.0 1.2 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 ORY17097.1 - 5.9e-37 127.2 0.1 1.3e-36 126.1 0.0 1.6 2 0 0 2 2 2 1 DAK2 domain F-box PF00646.33 ORY17098.1 - 2e-05 24.3 0.3 4.1e-05 23.3 0.3 1.5 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 ORY17098.1 - 0.00051 19.9 0.5 0.00091 19.1 0.5 1.4 1 0 0 1 1 1 1 F-box Tn7_Tnp_TnsA_C PF08721.11 ORY17098.1 - 0.31 11.7 1.1 0.54 10.9 0.4 1.8 2 0 0 2 2 2 0 TnsA endonuclease C terminal F-box-like PF12937.7 ORY17098.1 - 2.4 8.1 4.9 0.62 10.0 0.5 2.2 2 0 0 2 2 2 0 F-box-like CFEM PF05730.11 ORY17099.1 - 9.5e-05 22.4 1.7 0.00016 21.7 1.7 1.3 1 0 0 1 1 1 1 CFEM domain Kazal_1 PF00050.21 ORY17099.1 - 0.099 12.7 1.1 0.18 11.8 1.1 1.4 1 0 0 1 1 1 0 Kazal-type serine protease inhibitor domain Phage_term_sma PF07141.11 ORY17099.1 - 0.18 11.6 0.0 0.23 11.2 0.0 1.1 1 0 0 1 1 1 0 Putative bacteriophage terminase small subunit MFS_1 PF07690.16 ORY17100.1 - 1.7e-43 148.9 45.6 2.9e-43 148.2 45.6 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 ORY17100.1 - 5.4e-14 51.5 13.4 9.7e-14 50.7 13.4 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 ORY17100.1 - 2.6e-13 49.6 14.5 2.6e-13 49.6 14.5 2.8 2 1 1 3 3 3 1 Sugar (and other) transporter HDPD PF02924.14 ORY17100.1 - 0.087 12.9 0.0 0.11 12.6 0.0 1.4 1 1 0 1 1 1 0 Bacteriophage lambda head decoration protein D OATP PF03137.20 ORY17100.1 - 0.52 8.5 12.2 2.8 6.1 12.2 1.9 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family p450 PF00067.22 ORY17101.1 - 7e-53 180.0 0.0 8.6e-53 179.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ADH_zinc_N PF00107.26 ORY17103.1 - 1.9e-11 44.0 0.0 3.3e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ORY17103.1 - 1.3e-06 28.2 0.3 5.1e-06 26.3 0.2 2.0 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 ORY17103.1 - 0.0047 18.0 0.0 0.011 16.8 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ketoacyl-synt PF00109.26 ORY17104.1 - 2.8e-75 253.2 0.0 5.8e-75 252.1 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain AMP-binding PF00501.28 ORY17104.1 - 6.5e-71 239.1 0.0 3.1e-70 236.9 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme Condensation PF00668.20 ORY17104.1 - 4.7e-57 193.7 0.0 7.4e-57 193.0 0.0 1.2 1 0 0 1 1 1 1 Condensation domain KR PF08659.10 ORY17104.1 - 2.5e-55 187.2 0.2 5.5e-53 179.5 0.1 2.5 2 0 0 2 2 2 1 KR domain PS-DH PF14765.6 ORY17104.1 - 5.6e-48 163.7 0.0 8.8e-48 163.0 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 ORY17104.1 - 6.3e-41 140.9 0.0 1.2e-40 140.0 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain NAD_binding_4 PF07993.12 ORY17104.1 - 7.1e-27 94.2 0.0 1.4e-25 90.0 0.0 2.6 2 1 0 2 2 2 1 Male sterility protein Ketoacyl-synt_C PF02801.22 ORY17104.1 - 5.8e-25 87.6 0.0 1.3e-24 86.4 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 ORY17104.1 - 1.3e-18 67.6 0.1 9e-18 64.9 0.0 2.7 2 0 0 2 2 1 1 Methyltransferase domain PP-binding PF00550.25 ORY17104.1 - 5.7e-16 58.6 1.4 8.3e-12 45.3 0.1 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site KAsynt_C_assoc PF16197.5 ORY17104.1 - 8.7e-15 55.2 0.0 2.7e-14 53.6 0.0 1.9 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_23 PF13489.6 ORY17104.1 - 2.9e-14 53.2 0.0 6.7e-14 52.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY17104.1 - 1.3e-13 51.4 0.0 7.3e-13 49.1 0.0 2.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY17104.1 - 1.2e-12 47.9 0.0 3.1e-12 46.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY17104.1 - 1.2e-12 48.3 0.0 1e-11 45.3 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain adh_short PF00106.25 ORY17104.1 - 9e-11 41.6 0.1 6.6e-09 35.5 0.1 3.2 3 1 0 3 3 3 1 short chain dehydrogenase Epimerase PF01370.21 ORY17104.1 - 8.7e-09 35.2 0.0 2.4e-07 30.5 0.0 2.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Ubie_methyltran PF01209.18 ORY17104.1 - 1.4e-08 34.3 0.0 2.9e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family adh_short_C2 PF13561.6 ORY17104.1 - 1.1e-06 28.4 0.0 1.7e-05 24.5 0.0 2.4 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Thiolase_N PF00108.23 ORY17104.1 - 1.3e-06 27.9 0.3 1.4e-05 24.6 0.2 2.5 2 0 0 2 2 2 1 Thiolase, N-terminal domain Methyltransf_16 PF10294.9 ORY17104.1 - 5.1e-05 23.1 0.0 0.00011 22.0 0.0 1.4 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_PK PF05891.12 ORY17104.1 - 0.00046 19.8 0.0 0.00095 18.7 0.0 1.4 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase NodS PF05401.11 ORY17104.1 - 0.00074 19.2 0.0 0.0016 18.1 0.0 1.5 1 0 0 1 1 1 1 Nodulation protein S (NodS) 3Beta_HSD PF01073.19 ORY17104.1 - 0.0014 17.7 0.0 0.85 8.6 0.0 2.3 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family AMP-binding_C PF13193.6 ORY17104.1 - 0.0069 17.3 1.1 0.11 13.5 0.0 3.5 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain Semialdhyde_dh PF01118.24 ORY17104.1 - 0.039 14.4 0.1 0.65 10.4 0.0 2.7 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 ORY17104.1 - 0.093 11.8 0.1 2.8 7.0 0.0 2.3 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein RrnaAD PF00398.20 ORY17104.1 - 0.14 11.2 0.0 0.27 10.3 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_8 PF05148.15 ORY17104.1 - 0.18 11.6 0.0 0.39 10.5 0.0 1.5 1 0 0 1 1 1 0 Hypothetical methyltransferase Transp_cyt_pur PF02133.15 ORY17106.1 - 4.5e-152 506.9 36.1 5.8e-152 506.5 36.1 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Rad4 PF03835.15 ORY17107.1 - 5e-14 52.2 0.1 1.1e-13 51.1 0.1 1.6 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Transglut_core PF01841.19 ORY17107.1 - 7.7e-10 39.2 0.7 1.8e-09 38.0 0.7 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily YdjO PF14169.6 ORY17107.1 - 0.037 13.8 0.7 3.2 7.6 0.0 2.4 2 0 0 2 2 2 0 Cold-inducible protein YdjO CRCB PF02537.15 ORY17110.1 - 1.4e-33 115.0 18.3 1.6e-20 73.2 9.5 2.9 2 1 0 2 2 2 2 CrcB-like protein, Camphor Resistance (CrcB) UPRTase PF14681.6 ORY17111.1 - 1.4e-71 240.2 0.0 1.6e-71 240.1 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 ORY17111.1 - 9.8e-08 31.7 0.2 2.7e-07 30.2 0.2 1.6 1 1 0 1 1 1 1 Phosphoribosyl transferase domain Pribosyl_synth PF14572.6 ORY17111.1 - 0.12 12.5 0.0 0.17 11.9 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyl synthetase-associated domain DOT1 PF08123.13 ORY17112.1 - 3.1e-52 177.1 0.0 4e-52 176.7 0.0 1.1 1 0 0 1 1 1 1 Histone methylation protein DOT1 Lin-8 PF03353.15 ORY17113.1 - 0.061 12.9 0.4 0.08 12.5 0.4 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Rrn6 PF10214.9 ORY17113.1 - 0.36 9.3 5.8 0.37 9.2 5.8 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor TFIIA PF03153.13 ORY17113.1 - 2.9 7.8 7.7 3.9 7.4 7.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ndc1_Nup PF09531.10 ORY17113.1 - 3.9 6.0 10.7 5.3 5.6 10.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RhoGAP PF00620.27 ORY17115.1 - 6.5e-37 126.7 0.0 1e-36 126.0 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain zf-Tim10_DDP PF02953.15 ORY17116.1 - 3.7e-19 68.1 5.6 5.3e-19 67.6 5.6 1.3 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.13 ORY17116.1 - 0.0073 16.0 3.8 0.12 12.1 3.7 2.1 1 1 1 2 2 2 2 Eukaryotic protein of unknown function (DUF842) Asp_Glu_race PF01177.22 ORY17117.1 - 0.046 13.6 0.0 0.079 12.8 0.0 1.5 1 1 0 1 1 1 0 Asp/Glu/Hydantoin racemase F-box-like PF12937.7 ORY17118.1 - 3.7e-06 26.7 7.4 8.4e-06 25.6 0.4 3.0 3 1 0 3 3 3 2 F-box-like F-box PF00646.33 ORY17118.1 - 5.8e-06 26.0 4.6 0.001 18.9 2.3 3.2 2 1 0 2 2 2 2 F-box domain DUF4449 PF14613.6 ORY17119.1 - 4.8e-70 234.9 5.7 6.6e-70 234.4 3.7 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF4449) RbsD_FucU PF05025.13 ORY17119.1 - 0.0075 16.7 0.2 0.059 13.8 0.2 2.5 2 0 0 2 2 2 1 RbsD / FucU transport protein family Prp18 PF02840.15 ORY17119.1 - 0.58 10.2 0.0 0.58 10.2 0.0 3.3 3 2 1 4 4 4 0 Prp18 domain LPP PF04728.13 ORY17119.1 - 2.3 8.7 7.6 8.7 6.8 0.7 3.6 3 0 0 3 3 3 0 Lipoprotein leucine-zipper bZIP_2 PF07716.15 ORY17120.1 - 2.5e-06 27.5 6.0 0.0096 16.0 0.9 2.5 2 0 0 2 2 2 2 Basic region leucine zipper DUF3293 PF11697.8 ORY17120.1 - 0.0017 18.8 0.2 0.011 16.2 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3293) bZIP_1 PF00170.21 ORY17120.1 - 0.012 15.7 6.8 0.34 11.0 0.2 2.4 2 0 0 2 2 2 0 bZIP transcription factor Sec2p PF06428.11 ORY17121.1 - 2.6e-13 49.7 9.5 2.6e-13 49.7 9.5 2.1 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p Jnk-SapK_ap_N PF09744.9 ORY17121.1 - 0.006 16.8 10.9 0.19 11.9 6.3 2.3 2 0 0 2 2 2 1 JNK_SAPK-associated protein-1 CLZ PF16526.5 ORY17121.1 - 0.0093 16.3 14.9 0.041 14.2 6.0 2.8 3 0 0 3 3 3 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF3247 PF11607.8 ORY17121.1 - 0.017 15.4 2.2 1.5 9.1 0.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF3247) ADIP PF11559.8 ORY17121.1 - 0.059 13.5 14.0 0.085 12.9 7.6 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding zf-ISL3 PF14690.6 ORY17121.1 - 0.11 13.2 0.1 0.2 12.3 0.1 1.4 1 0 0 1 1 1 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-ribbon_3 PF13248.6 ORY17121.1 - 0.11 11.9 0.2 0.21 11.1 0.2 1.4 1 0 0 1 1 1 0 zinc-ribbon domain HAUS-augmin3 PF14932.6 ORY17121.1 - 0.13 11.8 6.9 1.3 8.6 4.4 2.3 2 1 0 2 2 2 0 HAUS augmin-like complex subunit 3 MAD PF05557.13 ORY17121.1 - 0.14 10.5 9.4 0.55 8.5 0.1 2.1 2 0 0 2 2 2 0 Mitotic checkpoint protein SYCE1 PF15233.6 ORY17121.1 - 0.16 12.1 10.0 0.043 13.9 6.8 1.6 2 0 0 2 2 2 0 Synaptonemal complex central element protein 1 DUF4795 PF16043.5 ORY17121.1 - 0.17 11.5 7.8 4.2 6.9 3.8 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4795) DUF4407 PF14362.6 ORY17121.1 - 0.24 10.7 9.0 0.88 8.9 9.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) GerPC PF10737.9 ORY17121.1 - 0.24 11.4 2.1 4.3 7.3 0.1 2.2 2 0 0 2 2 2 0 Spore germination protein GerPC DASH_Spc19 PF08287.11 ORY17121.1 - 0.32 10.9 12.0 0.14 12.0 1.1 2.3 1 1 1 2 2 2 0 Spc19 Striatin PF08232.12 ORY17121.1 - 0.7 10.5 13.0 1.1 9.9 0.0 2.9 2 1 0 3 3 3 0 Striatin family DUF5082 PF16888.5 ORY17121.1 - 0.71 10.2 7.7 5.2 7.4 0.4 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF5082) Ax_dynein_light PF10211.9 ORY17121.1 - 0.8 9.6 12.8 1.8 8.5 0.1 2.2 2 0 0 2 2 2 0 Axonemal dynein light chain Spc24 PF08286.11 ORY17121.1 - 1.1 9.6 8.0 21 5.4 0.0 2.8 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 ZapB PF06005.12 ORY17121.1 - 1.4 9.4 12.1 11 6.5 0.0 2.4 2 1 0 2 2 2 0 Cell division protein ZapB APG6_N PF17675.1 ORY17121.1 - 1.4 9.4 15.8 32 5.1 12.3 2.7 2 1 0 2 2 2 0 Apg6 coiled-coil region DUF5446 PF17522.2 ORY17121.1 - 1.7 8.9 8.5 8.2 6.7 1.6 2.8 1 1 1 2 2 2 0 Family of unknown function (DUF5446) SLX9 PF15341.6 ORY17121.1 - 1.7 9.0 10.8 0.84 10.0 7.8 1.8 2 0 0 2 2 2 0 Ribosome biogenesis protein SLX9 V_ATPase_I PF01496.19 ORY17121.1 - 1.9 6.3 3.0 5.7 4.7 2.5 1.7 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DUF2072 PF09845.9 ORY17121.1 - 1.9 8.7 6.1 17 5.7 0.0 2.2 2 0 0 2 2 2 0 Zn-ribbon containing protein Nnf1 PF03980.14 ORY17121.1 - 2.3 8.6 10.8 0.41 11.0 5.8 2.0 2 0 0 2 2 2 0 Nnf1 FAM184 PF15665.5 ORY17121.1 - 3.9 7.2 14.4 8.3 6.1 8.5 2.1 2 0 0 2 2 2 0 Family with sequence similarity 184, A and B BST2 PF16716.5 ORY17121.1 - 5.4 7.7 13.0 3.5 8.3 0.7 3.2 2 1 1 3 3 3 0 Bone marrow stromal antigen 2 TMF_DNA_bd PF12329.8 ORY17121.1 - 5.6 7.0 16.0 6.1 6.9 0.1 3.1 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding ABC_tran_CTD PF16326.5 ORY17121.1 - 7.3 6.9 17.5 17 5.7 0.3 2.9 2 1 0 2 2 2 0 ABC transporter C-terminal domain DUF724 PF05266.14 ORY17121.1 - 7.9 6.3 15.5 6.2 6.6 0.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF724) DHR10 PF18595.1 ORY17121.1 - 8.3 6.5 22.8 0.51 10.4 0.6 2.9 2 1 0 2 2 2 0 Designed helical repeat protein 10 domain Spc7 PF08317.11 ORY17121.1 - 9.3 5.0 15.7 7.3 5.4 0.4 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein SH3_1 PF00018.28 ORY17122.1 - 3.4e-05 23.3 0.0 8e-05 22.2 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 ORY17122.1 - 0.045 13.6 0.0 0.12 12.3 0.0 1.8 1 0 0 1 1 1 0 Variant SH3 domain HET PF06985.11 ORY17124.1 - 2.6e-07 31.1 0.1 3.8e-07 30.5 0.1 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Sec3_C_2 PF15278.6 ORY17124.1 - 0.11 12.8 0.0 0.16 12.4 0.0 1.2 1 0 0 1 1 1 0 Sec3 exocyst complex subunit Glyco_hydro_18 PF00704.28 ORY17125.1 - 6.5e-56 190.3 0.1 7.7e-56 190.1 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 polyprenyl_synt PF00348.17 ORY17126.1 - 5.6e-64 215.7 0.0 7.1e-64 215.3 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Pex14_N PF04695.13 ORY17126.1 - 0.018 15.7 2.7 0.027 15.1 2.7 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region F-box-like_2 PF13013.6 ORY17127.1 - 0.0091 16.0 0.3 0.018 15.0 0.1 1.7 2 0 0 2 2 2 1 F-box-like domain WD40 PF00400.32 ORY17128.1 - 7.6e-05 23.4 2.5 4.1 8.4 0.2 4.9 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY17128.1 - 0.011 16.1 0.0 4.2 7.7 0.0 3.2 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain CD34_antigen PF06365.12 ORY17129.1 - 0.0043 16.7 0.0 0.0048 16.5 0.0 1.1 1 0 0 1 1 1 1 CD34/Podocalyxin family DUF1970 PF09301.10 ORY17129.1 - 0.0079 16.4 0.0 0.0098 16.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1970) FAM176 PF14851.6 ORY17129.1 - 0.0093 15.6 0.0 0.012 15.3 0.0 1.1 1 0 0 1 1 1 1 FAM176 family TMEM190 PF15431.6 ORY17129.1 - 0.014 15.5 0.0 0.017 15.3 0.0 1.1 1 0 0 1 1 1 0 Transmembrane protein 190 LYRIC PF15686.5 ORY17129.1 - 0.015 14.9 0.0 0.019 14.6 0.0 1.1 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family EphA2_TM PF14575.6 ORY17129.1 - 0.028 15.3 0.0 0.039 14.8 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4381 PF14316.6 ORY17129.1 - 0.076 13.2 0.1 0.086 13.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF3827 PF12877.7 ORY17129.1 - 0.13 10.6 0.0 0.15 10.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) MAP17 PF15807.5 ORY17129.1 - 0.16 12.2 0.0 0.18 12.0 0.0 1.1 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 TMEM154 PF15102.6 ORY17129.1 - 0.2 11.5 0.0 0.25 11.2 0.0 1.2 1 0 0 1 1 1 0 TMEM154 protein family UPF0560 PF10577.9 ORY17129.1 - 0.21 10.0 0.0 0.22 10.0 0.0 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 LapA_dom PF06305.11 ORY17129.1 - 0.27 11.1 3.1 0.47 10.3 3.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain LSR PF05624.14 ORY17129.1 - 1.7 8.7 5.9 2.5 8.2 5.9 1.2 1 0 0 1 1 1 0 Lipolysis stimulated receptor (LSR) K_channel_TID PF07941.11 ORY17129.1 - 3 8.3 11.5 5.5 7.5 11.5 1.4 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain SecY PF00344.20 ORY17130.1 - 1.5e-71 241.1 10.5 1.9e-71 240.8 10.5 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 ORY17130.1 - 1.6e-17 63.0 0.2 5e-17 61.4 0.2 2.0 1 0 0 1 1 1 1 Plug domain of Sec61p DUF2929 PF11151.8 ORY17130.1 - 2.1 8.7 8.2 0.14 12.5 1.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2929) RTA1 PF04479.13 ORY17131.1 - 8.5e-63 211.7 9.1 8.5e-63 211.7 9.1 1.9 1 1 1 2 2 2 1 RTA1 like protein DUF5392 PF17370.2 ORY17131.1 - 0.084 13.0 1.6 2.2 8.4 0.2 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5392) Zn_clus PF00172.18 ORY17132.1 - 4.9e-06 26.6 6.2 4.9e-06 26.6 6.2 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 ORY17132.1 - 1.7e-05 23.8 1.0 2.7e-05 23.2 1.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3367 PF11847.8 ORY17132.1 - 0.24 9.2 3.0 0.34 8.7 3.0 1.1 1 0 0 1 1 1 0 Alpha-(1->3)-arabinofuranosyltransferase Acetyltransf_1 PF00583.25 ORY17133.1 - 1.2e-09 38.4 0.0 2.6e-09 37.3 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ORY17133.1 - 5.4e-09 36.1 0.0 8.2e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ORY17133.1 - 1.1e-08 35.4 0.0 2.6e-08 34.2 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 ORY17133.1 - 2.2e-06 27.7 0.0 0.00042 20.4 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain FR47 PF08445.10 ORY17133.1 - 0.0015 18.5 0.0 0.0024 17.8 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 ORY17133.1 - 0.014 15.5 0.0 0.024 14.8 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Pkinase PF00069.25 ORY17134.1 - 1.8e-34 119.4 0.0 2.5e-34 118.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY17134.1 - 3.6e-23 82.2 0.0 5.8e-23 81.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 ORY17134.1 - 0.031 13.6 0.0 0.058 12.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Las1 PF04031.13 ORY17137.1 - 5.6e-41 140.2 1.0 1.4e-40 139.0 0.5 2.0 2 0 0 2 2 2 1 Las1-like UPF0052 PF01933.18 ORY17138.1 - 7.9e-66 222.3 0.0 1.1e-65 221.8 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 COMPASS-Shg1 PF05205.12 ORY17140.1 - 6.2e-22 78.2 0.0 1.4e-21 77.1 0.0 1.6 1 0 0 1 1 1 1 COMPASS (Complex proteins associated with Set1p) component shg1 TRAPP PF04051.16 ORY17141.1 - 3.8e-38 130.5 0.0 4.8e-38 130.1 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component zf-NADH-PPase PF09297.11 ORY17142.1 - 1.7 8.4 5.2 14 5.4 0.1 3.3 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain Ank_2 PF12796.7 ORY17143.1 - 4.8e-10 39.9 0.5 2.1e-05 25.0 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY17143.1 - 5.1e-07 30.1 0.3 1.2e-05 25.7 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 ORY17143.1 - 8.8e-06 25.9 1.2 1.9 9.1 0.0 3.2 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 ORY17143.1 - 1.6e-05 24.9 0.2 1.1 10.0 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 ORY17143.1 - 0.019 15.3 0.3 3.1 8.2 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeats (many copies) NACHT PF05729.12 ORY17144.1 - 5.7e-06 26.4 0.0 1.3e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 NACHT domain NACHT_N PF17100.5 ORY17144.1 - 0.00022 21.1 0.0 0.0004 20.3 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of NWD NACHT-NTPase AAA_16 PF13191.6 ORY17144.1 - 0.0011 19.3 0.0 0.0033 17.8 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 ORY17144.1 - 0.0087 16.2 0.0 0.05 13.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 ORY17144.1 - 0.041 14.3 0.0 0.21 12.0 0.0 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 ORY17144.1 - 0.063 13.6 0.0 0.23 11.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 ORY17144.1 - 0.067 13.2 0.0 0.15 12.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_11 PF13086.6 ORY17144.1 - 0.078 12.8 0.1 0.24 11.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain GvpD PF07088.11 ORY17144.1 - 0.082 11.5 0.0 0.16 10.5 0.0 1.4 1 0 0 1 1 1 0 GvpD gas vesicle protein Cofilin_ADF PF00241.20 ORY17145.1 - 0.026 14.3 0.0 0.076 12.8 0.0 1.9 1 0 0 1 1 1 0 Cofilin/tropomyosin-type actin-binding protein OHCU_decarbox PF09349.10 ORY17146.1 - 3.6e-50 170.5 0.1 4.1e-50 170.3 0.1 1.0 1 0 0 1 1 1 1 OHCU decarboxylase Mito_carr PF00153.27 ORY17149.1 - 1.3e-53 178.9 1.6 5.6e-19 67.9 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3792 PF12670.7 ORY17149.1 - 0.086 13.0 0.9 0.21 11.8 0.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3792) WD40 PF00400.32 ORY17150.1 - 1.2e-15 57.6 6.9 3.2e-08 34.1 0.3 5.5 4 1 1 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY17150.1 - 2.3e-06 27.8 0.0 0.03 14.6 0.0 4.2 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain NACHT PF05729.12 ORY17151.1 - 6.7e-13 48.9 0.0 2e-12 47.4 0.0 1.8 1 0 0 1 1 1 1 NACHT domain Helo_like_N PF17111.5 ORY17151.1 - 2.7e-07 30.2 0.6 6.9e-07 28.8 0.6 1.8 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins AAA_16 PF13191.6 ORY17151.1 - 2.2e-06 28.2 0.1 1.4e-05 25.6 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 ORY17151.1 - 3e-06 27.7 0.0 2.5e-05 24.7 0.0 2.5 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 ORY17151.1 - 2.1e-05 24.8 0.2 9.6e-05 22.7 0.0 2.2 2 1 0 2 2 2 1 AAA domain SesA PF17107.5 ORY17151.1 - 2.3e-05 24.5 0.2 0.00017 21.7 0.3 2.4 3 0 0 3 3 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases ATPase_2 PF01637.18 ORY17151.1 - 0.00055 19.9 0.0 0.0014 18.6 0.0 1.6 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea NB-ARC PF00931.22 ORY17151.1 - 0.014 14.6 0.0 0.036 13.3 0.0 1.7 1 0 0 1 1 1 0 NB-ARC domain AAA_14 PF13173.6 ORY17151.1 - 0.015 15.3 0.1 0.26 11.3 0.0 3.0 2 1 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 ORY17151.1 - 0.026 14.3 0.0 0.29 10.9 0.0 2.2 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase NAD_binding_6 PF08030.12 ORY17151.1 - 0.032 14.3 0.1 6.1 6.9 0.1 2.9 2 0 0 2 2 2 0 Ferric reductase NAD binding domain RNA_helicase PF00910.22 ORY17151.1 - 0.052 13.9 0.0 0.13 12.7 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_17 PF13207.6 ORY17151.1 - 0.067 13.6 0.0 0.24 11.8 0.0 2.0 1 0 0 1 1 1 0 AAA domain CN_hydrolase PF00795.22 ORY17152.1 - 1.3e-33 116.5 0.4 1.6e-33 116.2 0.4 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase HMG_box PF00505.19 ORY17152.1 - 2.7e-15 56.5 0.1 5.8e-15 55.5 0.1 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 ORY17152.1 - 1.4e-14 54.4 0.5 3.1e-14 53.3 0.5 1.6 1 0 0 1 1 1 1 HMG-box domain YABBY PF04690.13 ORY17152.1 - 0.00055 20.5 0.0 0.00087 19.9 0.0 1.3 1 0 0 1 1 1 1 YABBY protein KASH_CCD PF14662.6 ORY17153.1 - 0.00019 21.3 11.5 0.00019 21.3 11.5 1.9 2 0 0 2 2 2 1 Coiled-coil region of CCDC155 or KASH BRO1 PF03097.18 ORY17153.1 - 0.0015 17.4 1.3 0.0023 16.8 1.3 1.2 1 0 0 1 1 1 1 BRO1-like domain HAP1_N PF04849.13 ORY17153.1 - 0.0018 17.6 4.4 0.0018 17.6 4.4 1.8 2 0 0 2 2 2 1 HAP1 N-terminal conserved region PHA_gran_rgn PF09650.10 ORY17153.1 - 0.0071 16.6 0.5 2 8.7 0.0 3.1 2 1 1 3 3 3 1 Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) Cep57_CLD_2 PF14197.6 ORY17153.1 - 0.26 11.4 11.5 0.065 13.3 3.6 2.5 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 CREPT PF16566.5 ORY17153.1 - 0.29 11.3 6.4 0.26 11.4 4.7 1.7 1 1 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour V_ATPase_I PF01496.19 ORY17153.1 - 2.7 5.8 7.5 3.2 5.5 7.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4407 PF14362.6 ORY17153.1 - 3.8 6.8 10.1 6.3 6.1 10.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HSP70 PF00012.20 ORY17154.1 - 0.0013 17.0 0.0 0.0046 15.2 0.0 1.8 2 0 0 2 2 2 1 Hsp70 protein DUF948 PF06103.11 ORY17155.1 - 0.46 10.8 11.7 1.5 9.2 0.1 3.5 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF2779 PF11074.8 ORY17155.1 - 1.3 9.5 11.6 0.061 13.8 1.8 2.7 2 1 0 2 2 2 0 Domain of unknown function(DUF2779) TcdB_N PF12918.7 ORY17155.1 - 2.9 8.3 9.8 1.6 9.1 1.5 3.6 3 0 0 3 3 3 0 TcdB toxin N-terminal helical domain FPP PF05911.11 ORY17155.1 - 3.8 5.6 54.0 0.024 12.8 38.1 2.3 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil DUF1664 PF07889.12 ORY17155.1 - 4.4 7.3 26.3 0.44 10.6 4.2 4.2 1 1 3 5 5 5 0 Protein of unknown function (DUF1664) DapH_N PF08503.10 ORY17156.1 - 0.072 13.3 1.2 0.2 11.9 0.1 2.4 2 0 0 2 2 2 0 Tetrahydrodipicolinate succinyltransferase N-terminal DUF5127 PF17168.4 ORY17157.1 - 1.5e-86 289.9 5.5 2.2e-86 289.3 5.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF4965 PF16335.5 ORY17157.1 - 6.2e-79 263.7 0.5 1.2e-78 262.8 0.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 ORY17157.1 - 3.1e-67 226.2 0.1 3.1e-67 226.2 0.1 2.4 3 1 0 3 3 3 1 Domain of unknown function (DUF1793) DUF4964 PF16334.5 ORY17157.1 - 4.4e-08 32.5 0.0 1.6e-07 30.8 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4964) Pkinase PF00069.25 ORY17158.1 - 3.2e-47 161.1 0.0 4.1e-47 160.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY17158.1 - 1.2e-26 93.6 0.0 6e-26 91.3 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase CLN3 PF02487.17 ORY17158.1 - 0.046 12.8 0.0 0.073 12.1 0.0 1.2 1 0 0 1 1 1 0 CLN3 protein Pkinase_fungal PF17667.1 ORY17158.1 - 0.054 12.3 0.0 0.098 11.4 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 ORY17158.1 - 0.072 12.0 0.1 0.11 11.4 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Arm PF00514.23 ORY17159.1 - 6.6e-75 245.1 32.9 8.2e-13 47.9 0.2 11.9 11 1 1 12 12 12 9 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 ORY17159.1 - 2.2e-19 69.6 11.4 3.9e-06 27.2 0.1 7.3 4 2 4 8 8 8 5 HEAT repeats HEAT_EZ PF13513.6 ORY17159.1 - 5.6e-19 68.2 15.7 1.1e-05 25.8 0.2 8.4 6 2 3 9 9 9 5 HEAT-like repeat HEAT PF02985.22 ORY17159.1 - 1.1e-16 59.5 15.2 0.059 13.7 0.0 9.6 10 0 0 10 10 9 4 HEAT repeat Adaptin_N PF01602.20 ORY17159.1 - 2.1e-12 46.4 7.8 4.5e-08 32.1 0.9 2.8 1 1 1 2 2 2 2 Adaptin N terminal region KAP PF05804.12 ORY17159.1 - 2.1e-12 46.0 0.4 3.7e-12 45.2 0.4 1.3 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) Arm_2 PF04826.13 ORY17159.1 - 3.9e-11 42.9 5.6 1.8e-06 27.6 2.2 2.4 1 1 0 2 2 2 2 Armadillo-like V-ATPase_H_N PF03224.14 ORY17159.1 - 2.1e-08 33.8 1.9 1.5e-05 24.4 0.8 3.2 1 1 1 2 2 2 2 V-ATPase subunit H Cnd1 PF12717.7 ORY17159.1 - 2.4e-06 27.7 8.1 0.0069 16.4 0.2 5.2 2 2 3 5 5 5 1 non-SMC mitotic condensation complex subunit 1 DUF3361 PF11841.8 ORY17159.1 - 3.4e-05 23.8 8.7 0.22 11.5 0.1 4.3 1 1 4 5 5 5 3 Domain of unknown function (DUF3361) DAP_B PF07930.12 ORY17159.1 - 0.0023 18.0 0.0 0.0041 17.1 0.0 1.3 1 0 0 1 1 1 1 D-aminopeptidase, domain B RTP1_C1 PF10363.9 ORY17159.1 - 0.0053 16.9 4.3 9.9 6.4 0.0 5.0 3 1 1 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 Atx10homo_assoc PF09759.9 ORY17159.1 - 0.0065 16.5 5.7 1.1 9.4 0.1 4.8 5 1 0 5 5 5 1 Spinocerebellar ataxia type 10 protein domain Proteasom_PSMB PF10508.9 ORY17159.1 - 0.0081 14.7 2.8 0.99 7.8 0.1 3.3 3 1 1 4 4 4 2 Proteasome non-ATPase 26S subunit UNC45-central PF11701.8 ORY17159.1 - 0.03 14.3 1.8 4.7 7.2 0.1 3.4 2 1 1 3 3 3 0 Myosin-binding striated muscle assembly central Vac14_Fab1_bd PF12755.7 ORY17159.1 - 0.057 14.0 0.1 2.4 8.8 0.0 3.1 1 1 2 3 3 3 0 Vacuolar 14 Fab1-binding region HEAT_PBS PF03130.16 ORY17159.1 - 0.073 13.8 10.9 9.8 7.2 0.8 6.5 7 0 0 7 7 5 0 PBS lyase HEAT-like repeat Vpu PF00558.19 ORY17159.1 - 0.3 10.9 1.7 0.46 10.3 0.3 2.0 2 0 0 2 2 2 0 Vpu protein RNA_pol_Rpc4 PF05132.14 ORY17160.1 - 3.9e-27 95.5 0.1 3.9e-27 95.5 0.1 5.9 3 2 1 5 5 5 1 RNA polymerase III RPC4 Ribonuc_red_sm PF00268.21 ORY17161.1 - 4.6e-122 406.9 0.9 5.6e-122 406.5 0.9 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain zf-H2C2_2 PF13465.6 ORY17162.1 - 8.8e-06 25.9 1.6 8.8e-06 25.9 1.6 5.0 7 0 0 7 7 7 1 Zinc-finger double domain zf-C2H2 PF00096.26 ORY17162.1 - 0.0012 19.2 30.1 0.066 13.7 2.0 4.9 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_8 PF15909.5 ORY17162.1 - 0.0094 16.2 0.9 0.0094 16.2 0.9 2.0 2 0 0 2 2 2 1 C2H2-type zinc ribbon zf-RAG1 PF10426.9 ORY17162.1 - 0.054 13.6 2.6 0.054 13.6 2.6 4.2 4 0 0 4 4 4 0 Recombination-activating protein 1 zinc-finger domain zf-C2H2_4 PF13894.6 ORY17162.1 - 0.06 14.2 28.9 0.46 11.4 1.5 4.9 4 0 0 4 4 4 0 C2H2-type zinc finger zf-Di19 PF05605.12 ORY17162.1 - 0.95 9.8 16.2 0.86 10.0 1.4 3.5 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding IBR PF01485.21 ORY17162.1 - 1.1 9.5 7.2 15 5.9 0.5 3.1 3 0 0 3 3 3 0 IBR domain, a half RING-finger domain DUF1644 PF07800.12 ORY17162.1 - 8.8 6.4 15.3 1.8 8.6 1.3 3.2 2 2 1 3 3 3 0 Protein of unknown function (DUF1644) Sugar_tr PF00083.24 ORY17165.1 - 7.2e-81 272.3 17.5 8.3e-81 272.1 17.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY17165.1 - 5.9e-34 117.5 43.3 4.4e-31 108.1 21.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 ORY17165.1 - 1.7e-08 33.5 14.0 0.0001 21.0 3.4 2.4 2 0 0 2 2 2 2 MFS/sugar transport protein TRI12 PF06609.13 ORY17165.1 - 2e-06 26.5 0.8 2e-06 26.5 0.8 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) UNC-93 PF05978.16 ORY17165.1 - 0.00054 19.7 1.4 0.00054 19.7 1.4 2.3 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 MFS_1_like PF12832.7 ORY17165.1 - 0.0018 17.2 7.0 0.064 12.1 0.3 2.4 2 1 0 2 2 2 2 MFS_1 like family HK PF02110.15 ORY17165.1 - 0.23 10.8 0.9 2 7.7 0.2 2.1 2 0 0 2 2 2 0 Hydroxyethylthiazole kinase family OATP PF03137.20 ORY17165.1 - 1.4 7.1 18.0 3.1 6.0 1.5 4.0 2 2 2 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family SNF2_N PF00176.23 ORY17166.1 - 8.7e-71 238.5 0.0 1.2e-70 238.0 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.11 ORY17166.1 - 2.3e-23 81.9 0.0 5.1e-23 80.8 0.0 1.6 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.31 ORY17166.1 - 3.1e-15 56.5 0.0 8.3e-15 55.1 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY17166.1 - 0.00012 22.1 0.0 0.00038 20.5 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.25 ORY17166.1 - 0.00034 20.4 9.0 0.00034 20.4 9.0 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 ORY17166.1 - 0.00076 19.3 4.8 0.0022 17.8 4.8 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 ORY17166.1 - 0.00077 19.3 6.3 0.0017 18.1 6.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORY17166.1 - 0.00082 19.7 8.3 0.0024 18.2 8.3 1.9 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 ORY17166.1 - 0.0074 16.3 5.2 0.0074 16.3 5.2 2.2 2 0 0 2 2 2 1 RING-type zinc-finger PLU-1 PF08429.11 ORY17166.1 - 0.0078 15.4 0.7 0.017 14.3 0.7 1.5 1 0 0 1 1 1 1 PLU-1-like protein ERCC3_RAD25_C PF16203.5 ORY17166.1 - 0.067 12.4 0.0 0.15 11.3 0.0 1.5 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase zf-RING_5 PF14634.6 ORY17166.1 - 1.2 9.1 10.3 0.41 10.6 6.7 2.2 2 1 0 2 2 2 0 zinc-RING finger domain SQS_PSY PF00494.19 ORY17167.1 - 7.9e-53 179.6 0.1 1.1e-52 179.1 0.1 1.2 1 0 0 1 1 1 1 Squalene/phytoene synthase Kelch_5 PF13854.6 ORY17168.1 - 1.6e-13 50.3 8.5 1.1e-12 47.6 0.1 4.7 5 0 0 5 5 5 1 Kelch motif Kelch_4 PF13418.6 ORY17168.1 - 6.4e-07 29.3 8.7 0.065 13.2 0.1 4.7 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_6 PF13964.6 ORY17168.1 - 2e-06 27.9 18.0 0.23 11.8 0.1 6.0 5 1 1 6 6 6 3 Kelch motif Kelch_3 PF13415.6 ORY17168.1 - 8e-05 22.8 8.8 0.095 13.0 0.2 5.4 4 0 0 4 4 4 1 Galactose oxidase, central domain Herpes_gE PF02480.16 ORY17168.1 - 0.044 12.5 0.0 0.061 12.1 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Orthoreo_P10 PF07204.11 ORY17168.1 - 0.14 12.1 0.1 0.29 11.1 0.1 1.4 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 Kelch_1 PF01344.25 ORY17168.1 - 0.24 11.0 7.7 30 4.3 0.1 5.3 6 0 0 6 6 6 0 Kelch motif Kelch_2 PF07646.15 ORY17168.1 - 0.54 10.3 13.2 29 4.8 0.7 6.5 7 0 0 7 7 7 0 Kelch motif Asp PF00026.23 ORY17170.1 - 4.4e-11 42.8 1.0 5e-08 32.7 0.1 2.1 2 0 0 2 2 2 2 Eukaryotic aspartyl protease VSP PF03302.13 ORY17170.1 - 0.14 11.0 2.4 0.21 10.4 2.4 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein PTP_tm PF18861.1 ORY17170.1 - 0.17 11.8 1.1 0.51 10.3 1.1 1.8 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J DUF4690 PF15756.5 ORY17170.1 - 0.28 11.8 1.3 1 10.0 0.3 2.4 2 0 0 2 2 2 0 Small Novel Rich in Cartilage Zn_clus PF00172.18 ORY17171.1 - 9e-09 35.3 9.5 1.6e-08 34.5 9.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 ORY17171.1 - 5.1e-05 22.3 4.7 0.00049 19.0 2.8 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain MFS_1 PF07690.16 ORY17172.1 - 1.2e-49 169.2 31.8 1.2e-49 169.2 31.8 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY17172.1 - 4.6e-15 55.4 5.2 4.6e-15 55.4 5.2 2.9 2 1 1 3 3 3 2 Sugar (and other) transporter MFS_4 PF06779.14 ORY17172.1 - 3.4e-07 29.9 3.4 3.4e-07 29.9 3.4 2.2 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB DUF2583 PF10762.9 ORY17172.1 - 0.051 14.0 0.3 0.22 12.0 0.3 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2583) TRI12 PF06609.13 ORY17172.1 - 0.072 11.5 6.2 0.01 14.3 2.2 1.5 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) Syndecan PF01034.20 ORY17174.1 - 0.27 11.2 0.3 0.55 10.2 0.3 1.4 1 0 0 1 1 1 0 Syndecan domain Rick_17kDa_Anti PF05433.15 ORY17175.1 - 9.1e-05 22.2 13.5 0.0074 16.1 15.6 2.2 1 1 2 3 3 3 3 Glycine zipper 2TM domain Gly-zipper_YMGG PF13441.6 ORY17175.1 - 0.22 11.3 12.6 0.46 10.3 12.6 1.5 1 0 0 1 1 1 0 YMGG-like Gly-zipper TraT PF05818.12 ORY17175.1 - 1.5 8.4 6.1 2.8 7.6 6.1 1.3 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein Ribosomal_L22e PF01776.17 ORY17176.1 - 2.4e-48 163.0 1.3 2.9e-48 162.8 1.3 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family dDENN PF03455.19 ORY17176.1 - 0.11 12.5 0.5 0.56 10.2 0.0 2.4 2 2 1 3 3 3 0 dDENN domain Glyco_hydro_61 PF03443.14 ORY17177.1 - 6.5e-55 186.3 0.9 7.8e-55 186.0 0.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 NODP PF07684.12 ORY17177.1 - 0.34 11.1 2.2 0.64 10.2 2.2 1.4 1 0 0 1 1 1 0 NOTCH protein p450 PF00067.22 ORY17178.1 - 2.1e-43 148.7 0.0 3.1e-43 148.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 BacA PF02673.18 ORY17179.1 - 0.077 12.7 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Bacitracin resistance protein BacA 2OG-FeII_Oxy_2 PF13532.6 ORY17180.1 - 6.5e-22 78.7 0.0 1.9e-21 77.2 0.0 1.7 3 0 0 3 3 3 1 2OG-Fe(II) oxygenase superfamily MIT PF04212.18 ORY17181.1 - 4.3e-10 39.5 1.0 8.1e-10 38.6 1.0 1.5 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain MutL PF13941.6 ORY17181.1 - 0.033 12.8 0.7 0.084 11.4 0.5 1.7 1 1 1 2 2 2 0 MutL protein Cyclase PF04199.13 ORY17182.1 - 1.1e-14 54.8 0.1 1.6e-14 54.3 0.1 1.2 1 0 0 1 1 1 1 Putative cyclase GMC_oxred_N PF00732.19 ORY17207.1 - 1.7e-62 211.5 0.0 1.4e-61 208.4 0.0 2.0 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 ORY17207.1 - 1.1e-24 87.5 0.0 2.6e-24 86.4 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 ORY17207.1 - 3e-06 27.1 1.2 7.1e-05 22.6 1.2 2.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ORY17207.1 - 1.3e-05 24.6 0.2 0.027 13.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ORY17207.1 - 2.4e-05 23.6 1.0 0.16 11.0 0.6 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 ORY17207.1 - 0.00045 20.4 0.0 0.0016 18.6 0.0 2.0 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 ORY17207.1 - 0.00074 18.9 0.0 0.39 9.9 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 ORY17207.1 - 0.0046 16.1 0.0 0.018 14.1 0.0 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein HI0933_like PF03486.14 ORY17207.1 - 0.033 12.9 0.6 1.1 7.8 0.1 2.1 2 0 0 2 2 2 0 HI0933-like protein TrkA_N PF02254.18 ORY17207.1 - 0.039 14.2 0.5 0.13 12.5 0.4 1.9 2 0 0 2 2 2 0 TrkA-N domain Pyr_redox PF00070.27 ORY17207.1 - 0.06 13.9 3.0 0.1 13.2 0.7 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ORY17207.1 - 0.13 12.2 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Gly-zipper_YMGG PF13441.6 ORY17208.1 - 0.011 15.5 0.3 0.02 14.6 0.3 1.4 1 0 0 1 1 1 0 YMGG-like Gly-zipper Gly-zipper_Omp PF13488.6 ORY17208.1 - 0.014 15.3 0.9 0.029 14.4 0.9 1.5 1 0 0 1 1 1 0 Glycine zipper PhyH PF05721.13 ORY17209.1 - 6.4e-21 75.6 2.5 1.2e-18 68.2 1.1 2.2 1 1 1 2 2 2 2 Phytanoyl-CoA dioxygenase (PhyH) DB_JBP1 PF18526.1 ORY17209.1 - 0.095 12.6 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Thymine dioxygenase JBP1 DNA-binding domain MFS_1 PF07690.16 ORY17210.1 - 2.7e-42 144.9 23.6 1.3e-33 116.4 9.0 3.0 1 1 2 3 3 3 2 Major Facilitator Superfamily MFS_2 PF13347.6 ORY17210.1 - 1.7e-08 33.5 12.0 5.1e-06 25.3 0.2 3.6 2 2 2 4 4 4 2 MFS/sugar transport protein OATP PF03137.20 ORY17210.1 - 1.1e-07 30.5 2.6 6.3e-05 21.5 0.6 2.5 1 1 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family DUF4227 PF14004.6 ORY17210.1 - 0.12 12.4 1.0 1.2 9.2 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4227) YesK PF14150.6 ORY17210.1 - 0.29 11.4 4.6 0.26 11.5 1.8 2.5 2 0 0 2 2 2 0 YesK-like protein Peptidase_M48_N PF16491.5 ORY17210.1 - 0.68 9.8 0.0 0.68 9.8 0.0 2.7 4 0 0 4 4 4 0 CAAX prenyl protease N-terminal, five membrane helices MFS_3 PF05977.13 ORY17210.1 - 3.5 5.9 16.3 0.24 9.7 2.2 2.1 2 0 0 2 2 2 0 Transmembrane secretion effector eIF-5_eIF-2B PF01873.17 ORY17211.1 - 8.5e-23 80.5 1.2 1.5e-22 79.7 1.2 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 Elf1 PF05129.13 ORY17211.1 - 0.081 13.0 0.9 0.18 11.9 0.9 1.6 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like zf-Dof PF02701.15 ORY17211.1 - 0.12 12.6 3.4 0.09 12.9 1.4 1.9 2 0 0 2 2 2 0 Dof domain, zinc finger PocR PF10114.9 ORY17211.1 - 0.19 11.5 0.5 6.1 6.6 0.0 2.1 2 0 0 2 2 2 0 Sensory domain found in PocR NAD_binding_10 PF13460.6 ORY17212.1 - 2e-14 53.9 0.0 2.9e-14 53.4 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 ORY17212.1 - 2.1e-12 47.1 0.0 2.5e-12 46.9 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Sacchrp_dh_NADP PF03435.18 ORY17212.1 - 6.2e-05 23.3 0.0 0.00011 22.4 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 ORY17212.1 - 0.0005 19.6 0.0 0.00085 18.8 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 ORY17212.1 - 0.0052 17.2 0.0 0.0085 16.5 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 ORY17212.1 - 0.028 14.5 0.0 0.05 13.7 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus TrkA_N PF02254.18 ORY17212.1 - 0.054 13.8 0.0 0.1 12.9 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Dodecin PF07311.12 ORY17212.1 - 0.12 12.6 0.0 0.3 11.4 0.0 1.6 1 0 0 1 1 1 0 Dodecin FaeA PF04703.12 ORY17212.1 - 0.16 12.4 0.2 1.4 9.3 0.0 2.3 1 1 1 2 2 2 0 FaeA-like protein adh_short PF00106.25 ORY17213.1 - 1.8e-36 125.5 0.0 2.5e-36 125.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY17213.1 - 2.9e-36 125.2 0.0 3.7e-36 124.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY17213.1 - 7.3e-06 26.0 0.0 1e-05 25.5 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ORY17213.1 - 0.023 14.1 0.0 0.052 13.0 0.0 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 ORY17213.1 - 0.04 13.3 0.0 0.087 12.2 0.0 1.5 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.6 ORY17213.1 - 0.077 12.9 0.0 0.46 10.4 0.0 2.0 1 1 0 1 1 1 0 NAD(P)H-binding 2-Hacid_dh_C PF02826.19 ORY17214.1 - 2.5e-56 189.9 0.0 3.4e-56 189.4 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 ORY17214.1 - 1.2e-19 70.3 0.0 1.4e-19 70.1 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 ORY17214.1 - 0.00097 19.3 0.1 0.002 18.3 0.1 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 ORY17214.1 - 0.0068 16.0 0.1 0.011 15.3 0.1 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain Sugar_tr PF00083.24 ORY17215.1 - 1.7e-121 406.3 25.4 1.9e-121 406.1 25.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY17215.1 - 1.8e-23 83.1 26.8 1.8e-23 83.1 26.8 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily adh_short PF00106.25 ORY17218.1 - 3.9e-15 55.8 0.0 5.7e-07 29.2 0.0 2.2 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 ORY17218.1 - 2.5e-06 27.2 0.0 0.018 14.6 0.0 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase RmlD_sub_bind PF04321.17 ORY17218.1 - 0.036 13.2 0.0 0.14 11.3 0.0 1.7 2 0 0 2 2 2 0 RmlD substrate binding domain KR PF08659.10 ORY17218.1 - 0.12 12.2 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 KR domain Oxidored_FMN PF00724.20 ORY17220.1 - 1e-81 274.9 0.0 1.5e-81 274.4 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Cuticle_2 PF08184.11 ORY17221.1 - 0.11 12.5 0.0 0.27 11.3 0.0 1.7 1 0 0 1 1 1 0 Cuticle protein 7 isoform family HET PF06985.11 ORY17222.1 - 0.027 14.8 0.0 0.038 14.3 0.0 1.3 1 0 0 1 1 1 0 Heterokaryon incompatibility protein (HET) Acyltransf_C PF16076.5 ORY17222.1 - 0.039 14.1 0.0 0.059 13.5 0.0 1.5 1 1 0 1 1 1 0 Acyltransferase C-terminus SDF PF00375.18 ORY17223.1 - 3.3e-75 253.6 34.4 3.1e-68 230.6 30.3 2.0 1 1 1 2 2 2 2 Sodium:dicarboxylate symporter family CAAD PF14159.6 ORY17223.1 - 0.0037 17.1 3.0 0.0062 16.4 0.6 2.7 2 0 0 2 2 2 1 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase SoPB_HTH PF18090.1 ORY17223.1 - 0.11 12.7 0.3 0.61 10.3 0.1 2.3 2 0 0 2 2 2 0 Centromere-binding protein HTH domain AC_N PF16214.5 ORY17224.1 - 0.0061 15.8 0.4 0.009 15.2 0.4 1.2 1 0 0 1 1 1 1 Adenylyl cyclase N-terminal extracellular and transmembrane region LptF_LptG PF03739.14 ORY17224.1 - 0.02 13.8 3.8 0.047 12.5 3.8 1.7 1 1 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG Tautomerase_2 PF14552.6 ORY17224.1 - 0.035 14.2 0.7 0.074 13.2 0.7 1.5 1 0 0 1 1 1 0 Tautomerase enzyme KIP1 PF07765.12 ORY17224.1 - 0.078 13.1 4.9 0.22 11.7 4.9 1.7 1 0 0 1 1 1 0 KIP1-like protein Transp_cyt_pur PF02133.15 ORY17226.1 - 1.1e-12 47.5 11.5 1e-06 27.8 0.1 2.1 1 1 1 2 2 2 2 Permease for cytosine/purines, uracil, thiamine, allantoin Amidohydro_1 PF01979.20 ORY17227.1 - 2.9e-28 99.2 0.3 7.2e-25 88.0 0.3 2.8 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 ORY17227.1 - 0.00043 19.9 0.0 0.043 13.3 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family HET PF06985.11 ORY17228.1 - 4.2e-23 82.3 0.0 6.6e-23 81.7 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) AMP-binding PF00501.28 ORY17230.1 - 6.1e-76 255.7 0.0 1e-75 255.0 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme WD40 PF00400.32 ORY17230.1 - 1.9e-17 63.3 14.9 0.0042 17.9 0.1 8.7 9 0 0 9 9 9 4 WD domain, G-beta repeat AMP-binding_C PF13193.6 ORY17230.1 - 1.4e-14 54.8 0.2 5e-14 53.0 0.1 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ANAPC4_WD40 PF12894.7 ORY17230.1 - 3.3e-06 27.3 0.1 0.28 11.5 0.0 4.7 2 2 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 ORY17230.1 - 0.023 13.7 0.1 3.8 6.4 0.0 3.1 3 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein TFIIA PF03153.13 ORY17230.1 - 0.55 10.2 6.5 0.9 9.5 6.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit 2OG-FeII_Oxy_2 PF13532.6 ORY17231.1 - 9e-15 55.4 0.0 2.5e-14 53.9 0.0 1.7 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily SAD_SRA PF02182.17 ORY17231.1 - 0.065 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 SAD/SRA domain zf-tcix PF14952.6 ORY17231.1 - 1.4 8.6 3.8 3.3 7.4 3.8 1.5 1 0 0 1 1 1 0 Putative treble-clef, zinc-finger, Zn-binding Abhydrolase_1 PF00561.20 ORY17232.1 - 5.6e-14 52.4 0.0 1.4e-13 51.1 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORY17232.1 - 3.1e-13 50.9 0.0 1.2e-12 49.0 0.0 1.9 2 1 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORY17232.1 - 3.4e-08 33.1 0.0 6.8e-08 32.1 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 ORY17232.1 - 3.5e-07 29.2 0.0 5.3e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 Ndr family Esterase PF00756.20 ORY17232.1 - 0.001 18.8 0.0 0.0021 17.7 0.0 1.4 1 0 0 1 1 1 1 Putative esterase EthD PF07110.11 ORY17232.1 - 0.0019 19.3 0.2 0.43 11.7 0.0 2.7 2 0 0 2 2 2 1 EthD domain Abhydrolase_2 PF02230.16 ORY17232.1 - 0.11 12.3 0.0 0.44 10.3 0.0 1.9 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase MqsR_toxin PF15723.5 ORY17232.1 - 0.19 12.1 0.8 17 5.8 0.0 3.1 3 0 0 3 3 3 0 Motility quorum-sensing regulator, toxin of MqsA BAAT_C PF08840.11 ORY17232.1 - 0.2 11.5 0.0 0.37 10.7 0.0 1.4 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Lactonase PF10282.9 ORY17233.1 - 3.3e-15 56.2 0.0 4.5e-15 55.8 0.0 1.1 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Arylesterase PF01731.20 ORY17233.1 - 0.077 13.2 0.0 1.1 9.5 0.0 2.4 2 0 0 2 2 2 0 Arylesterase Dioxygenase_C PF00775.21 ORY17234.1 - 1.3e-39 135.5 0.0 2.1e-39 134.9 0.0 1.3 1 0 0 1 1 1 1 Dioxygenase Acyl-CoA_dh_1 PF00441.24 ORY17234.1 - 9e-39 133.1 0.5 1.5e-38 132.4 0.5 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 ORY17234.1 - 5e-32 110.9 0.1 9.6e-32 110.0 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Dioxygenase_N PF04444.14 ORY17234.1 - 3.4e-27 94.1 0.2 6.9e-27 93.1 0.2 1.6 1 0 0 1 1 1 1 Catechol dioxygenase N terminus Acyl-CoA_dh_M PF02770.19 ORY17234.1 - 6e-27 93.7 0.1 1.3e-26 92.6 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 ORY17234.1 - 6.7e-13 49.1 0.1 1.1e-12 48.3 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain CMD PF02627.20 ORY17234.1 - 2.2e-09 37.3 0.0 8.8e-09 35.3 0.0 2.0 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family CarboxypepD_reg PF13620.6 ORY17234.1 - 8.9e-05 22.7 0.0 0.0006 20.0 0.0 2.2 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain HpaB_N PF11794.8 ORY17234.1 - 0.00019 21.2 0.0 0.0004 20.1 0.0 1.5 1 0 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal HET PF06985.11 ORY17235.1 - 1.3e-23 84.0 0.0 2.7e-23 82.9 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Glyco_hydro_76 PF03663.14 ORY17236.1 - 5.5e-141 470.3 13.7 7.1e-141 470.0 13.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Carboxyl_trans PF01039.22 ORY17236.1 - 5.9e-138 460.6 0.2 8.9e-138 460.0 0.2 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain TRAM_LAG1_CLN8 PF03798.16 ORY17237.1 - 1e-44 152.7 19.3 1e-44 152.7 19.3 2.1 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 ORY17237.1 - 2e-21 75.4 0.1 2e-21 75.4 0.1 2.2 2 0 0 2 2 2 1 TRAM1-like protein Bax1-I PF01027.20 ORY17238.1 - 1.4e-52 178.5 24.9 1.7e-52 178.3 24.9 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 SH3_1 PF00018.28 ORY17239.1 - 1.1e-09 37.7 0.1 2.1e-09 36.9 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 ORY17239.1 - 1.7e-07 31.0 0.0 3.3e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 ORY17239.1 - 1.3e-06 28.0 0.0 2.3e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Dynactin_p22 PF07426.11 ORY17241.1 - 5.9e-06 26.2 0.2 8e-06 25.8 0.2 1.2 1 0 0 1 1 1 1 Dynactin subunit p22 Sec20 PF03908.13 ORY17241.1 - 0.028 14.3 0.2 0.1 12.6 0.1 1.9 1 1 1 2 2 2 0 Sec20 Aa_trans PF01490.18 ORY17242.1 - 3.9e-93 312.4 14.7 6e-93 311.8 14.7 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF2417 PF10329.9 ORY17242.1 - 0.038 13.4 6.0 1.7 8.0 0.2 3.4 3 1 0 3 3 3 0 Region of unknown function (DUF2417) ORMDL PF04061.14 ORY17242.1 - 0.19 11.5 7.2 0.069 13.0 1.4 2.8 2 1 0 2 2 2 0 ORMDL family TssN PF17555.2 ORY17242.1 - 0.73 9.2 7.3 1 8.7 0.0 3.0 2 1 1 3 3 3 0 Type VI secretion system, TssN EMP70 PF02990.16 ORY17242.1 - 7.2 5.1 17.1 0.17 10.5 6.7 2.6 3 0 0 3 3 3 0 Endomembrane protein 70 Ribosomal_S16 PF00886.19 ORY17243.1 - 4.8e-24 84.2 0.1 7e-24 83.7 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S16 YjeF_N PF03853.15 ORY17245.1 - 2e-34 118.9 0.0 2.4e-34 118.7 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus SL4P PF17618.2 ORY17245.1 - 0.13 12.3 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized Strongylid L4 protein WD40 PF00400.32 ORY17246.1 - 2.7e-08 34.3 0.0 0.013 16.4 0.0 2.9 2 0 0 2 2 2 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY17246.1 - 6.4e-05 23.2 0.0 0.17 12.2 0.0 2.5 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 ORY17246.1 - 0.011 14.7 0.0 2.8 6.8 0.0 2.5 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Gmad1 PF10647.9 ORY17246.1 - 0.011 15.5 0.4 0.44 10.3 0.0 2.8 3 0 0 3 3 3 0 Lipoprotein LpqB beta-propeller domain Nbas_N PF15492.6 ORY17246.1 - 0.065 12.6 0.0 0.57 9.5 0.0 2.0 1 1 1 2 2 2 0 Neuroblastoma-amplified sequence, N terminal Septin PF00735.18 ORY17247.1 - 1.7e-109 365.5 0.1 3.2e-109 364.5 0.0 1.5 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 ORY17247.1 - 3.1e-06 27.2 0.0 7.6e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 ORY17247.1 - 0.003 17.6 5.1 1 9.4 0.0 3.1 2 1 1 3 3 3 2 Dynamin family GTP_EFTU PF00009.27 ORY17247.1 - 0.0073 15.9 0.6 0.52 9.8 0.1 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 ORY17247.1 - 0.041 14.2 1.2 0.089 13.1 0.1 2.2 2 1 0 2 2 2 0 AAA domain AIG1 PF04548.16 ORY17247.1 - 0.045 13.1 0.0 0.045 13.1 0.0 1.7 2 0 0 2 2 2 0 AIG1 family RsgA_GTPase PF03193.16 ORY17247.1 - 0.05 13.5 0.8 0.05 13.5 0.8 3.0 3 1 0 3 3 3 0 RsgA GTPase Roc PF08477.13 ORY17247.1 - 0.066 13.4 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_23 PF13476.6 ORY17247.1 - 7.5 7.0 9.1 12 6.3 4.0 2.2 2 1 0 2 2 2 0 AAA domain PQ-loop PF04193.14 ORY17249.1 - 1.1e-06 28.3 15.0 2.8e-06 27.0 2.8 4.4 2 2 2 4 4 4 2 PQ loop repeat Ost5 PF05251.12 ORY17249.1 - 0.029 14.6 0.1 0.14 12.5 0.1 2.1 1 0 0 1 1 1 0 Oligosaccharyltransferase subunit 5 Y_phosphatase3 PF13350.6 ORY17250.1 - 1.6e-45 155.9 0.0 8e-45 153.6 0.0 2.1 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 ORY17250.1 - 0.0092 15.6 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 ORY17250.1 - 0.033 13.7 0.0 0.047 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DLIC PF05783.11 ORY17252.1 - 3.6e-34 118.4 0.4 2.2e-32 112.6 0.0 3.3 3 1 0 3 3 3 1 Dynein light intermediate chain (DLIC) RRM_1 PF00076.22 ORY17253.1 - 2.2e-16 59.4 0.0 4.8e-16 58.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 ORY17253.1 - 0.0097 16.0 0.0 0.021 15.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif RhoGEF67_u2 PF16614.5 ORY17253.1 - 0.26 11.4 6.2 0.25 11.4 4.7 1.9 1 1 1 2 2 2 0 Unstructured region two on RhoGEF 6 and 7 Sugar_tr PF00083.24 ORY17254.1 - 3.4e-63 214.1 14.9 4.2e-63 213.8 14.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter K-cyclin_vir_C PF09080.10 ORY17254.1 - 0.069 13.6 0.2 0.16 12.4 0.1 1.7 1 1 0 1 1 1 0 K cyclin, C terminal NMO PF03060.15 ORY17255.1 - 1e-28 100.7 12.9 1.3e-24 87.2 8.4 2.7 2 1 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.18 ORY17255.1 - 2.6e-06 26.7 2.9 3.8e-06 26.2 2.9 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 ORY17255.1 - 0.0001 21.5 1.2 0.0044 16.1 1.2 2.2 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 ORY17255.1 - 0.00015 21.0 0.7 0.00023 20.4 0.7 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase ThiG PF05690.14 ORY17255.1 - 0.08 12.2 0.4 0.13 11.6 0.4 1.2 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG Glyco_hydro_11 PF00457.17 ORY17256.1 - 2.9e-57 193.2 11.1 3.5e-57 192.9 11.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 SIMPL PF04402.14 ORY17257.1 - 1.8e-22 80.8 2.1 2.1e-22 80.6 2.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF541) NMO PF03060.15 ORY17258.1 - 2.4e-48 165.2 1.2 7.1e-48 163.7 1.2 1.6 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 ORY17258.1 - 4.2e-10 39.1 0.1 0.00044 19.3 0.3 2.3 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 ORY17258.1 - 3.5e-07 29.6 0.3 5.4e-07 28.9 0.3 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase DUF1902 PF08972.11 ORY17258.1 - 0.005 16.8 0.1 0.28 11.2 0.0 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF1902) His_biosynth PF00977.21 ORY17258.1 - 0.029 13.8 0.1 0.065 12.7 0.1 1.5 1 1 0 1 1 1 0 Histidine biosynthesis protein NanE PF04131.14 ORY17258.1 - 0.041 13.1 0.1 0.087 12.0 0.1 1.6 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase Glu_synthase PF01645.17 ORY17258.1 - 0.081 12.0 1.3 0.21 10.7 1.1 1.9 1 1 0 1 1 1 0 Conserved region in glutamate synthase SfLAP PF11139.8 ORY17258.1 - 0.23 10.9 3.0 2.5 7.5 0.2 2.2 2 0 0 2 2 2 0 Sap, sulfolipid-1-addressing protein GFA PF04828.14 ORY17259.1 - 6.1e-19 68.2 0.1 9.2e-19 67.6 0.1 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Pkinase PF00069.25 ORY17261.1 - 4.5e-30 104.9 0.0 2.8e-29 102.3 0.0 2.2 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY17261.1 - 6e-17 61.8 0.0 1e-16 61.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 ORY17261.1 - 0.0074 15.7 0.4 0.036 13.4 0.0 2.1 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 ORY17261.1 - 0.069 12.5 0.6 0.11 11.7 0.0 1.7 2 0 0 2 2 2 0 Kinase-like APH PF01636.23 ORY17261.1 - 0.17 11.8 4.5 6.9 6.5 0.0 2.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family adh_short PF00106.25 ORY17262.1 - 1.9e-31 109.1 0.0 2.6e-31 108.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY17262.1 - 5.5e-20 71.9 0.0 8.7e-20 71.3 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY17262.1 - 0.0014 18.5 0.0 0.038 13.9 0.0 2.2 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 ORY17262.1 - 0.084 12.3 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family AMP-binding PF00501.28 ORY17264.1 - 4.1e-93 312.3 0.0 5e-93 312.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORY17264.1 - 4.4e-21 75.7 0.2 1e-20 74.5 0.2 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Exo_endo_phos PF03372.23 ORY17265.1 - 6.1e-08 32.5 0.1 9.7e-08 31.8 0.1 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family adh_short_C2 PF13561.6 ORY17266.1 - 5.6e-54 183.2 0.1 7.4e-54 182.8 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY17266.1 - 3e-41 141.0 0.2 4.2e-41 140.6 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORY17266.1 - 3.9e-14 52.9 0.2 6e-14 52.4 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ORY17266.1 - 0.00095 18.7 0.0 0.0016 18.0 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ORY17266.1 - 0.019 14.4 0.0 4.6 6.5 0.0 2.1 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase 3HCDH_N PF02737.18 ORY17266.1 - 0.085 12.7 0.1 0.16 11.8 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RabGAP-TBC PF00566.18 ORY17267.1 - 2.6e-44 151.5 0.1 3.8e-44 150.9 0.1 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_6 PF13405.6 ORY17267.1 - 0.0007 19.3 1.0 0.04 13.8 0.2 3.1 2 0 0 2 2 2 1 EF-hand domain GRAM PF02893.20 ORY17267.1 - 0.025 14.5 0.0 0.095 12.6 0.0 1.9 2 0 0 2 2 2 0 GRAM domain EF-hand_1 PF00036.32 ORY17267.1 - 0.038 13.5 2.9 0.22 11.1 0.6 3.1 3 0 0 3 3 3 0 EF hand EF-hand_7 PF13499.6 ORY17267.1 - 0.039 14.4 3.3 0.034 14.6 1.1 2.1 2 0 0 2 2 2 0 EF-hand domain pair NVEALA PF14055.6 ORY17267.1 - 0.066 13.2 0.0 0.18 11.8 0.0 1.7 1 0 0 1 1 1 0 NVEALA protein EF-hand_5 PF13202.6 ORY17267.1 - 0.087 12.4 0.2 0.27 10.8 0.2 1.9 1 0 0 1 1 1 0 EF hand Sporozoite_P67 PF05642.11 ORY17267.1 - 0.36 8.8 5.1 0.78 7.8 5.1 1.5 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Helo_like_N PF17111.5 ORY17268.1 - 5.9e-05 22.5 2.3 5.9e-05 22.5 2.3 3.0 2 1 0 2 2 2 1 Fungal N-terminal domain of STAND proteins Zn_clus PF00172.18 ORY17268.1 - 0.00031 20.8 17.6 0.00058 19.9 9.9 2.8 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4055 PF13264.6 ORY17268.1 - 0.78 9.9 3.2 1.1 9.4 1.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4055) AA_permease_2 PF13520.6 ORY17270.1 - 7.9e-46 156.7 44.2 1e-45 156.4 44.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ORY17270.1 - 1.3e-17 63.6 36.4 1.7e-17 63.2 36.4 1.1 1 0 0 1 1 1 1 Amino acid permease Gly_transf_sug PF04488.15 ORY17272.1 - 4.1e-15 56.2 0.0 9.5e-15 55.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Annexin PF00191.20 ORY17275.1 - 8.3e-72 237.2 6.3 1.7e-19 69.7 0.1 4.2 4 0 0 4 4 4 4 Annexin DUF3574 PF12098.8 ORY17275.1 - 4.8e-05 23.1 0.4 4.1 7.3 0.0 4.2 4 0 0 4 4 4 2 Protein of unknown function (DUF3574) DUF5617 PF18493.1 ORY17275.1 - 0.11 12.6 0.1 0.56 10.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5617) GrpE PF01025.19 ORY17275.1 - 0.26 11.0 1.4 0.93 9.1 0.1 2.1 2 0 0 2 2 2 0 GrpE Nitroreductase PF00881.24 ORY17276.1 - 8.4e-16 58.5 0.0 1e-15 58.2 0.0 1.0 1 0 0 1 1 1 1 Nitroreductase family Lactonase PF10282.9 ORY17277.1 - 0.00026 20.4 1.8 0.0061 15.9 0.2 3.2 3 1 0 3 3 3 1 Lactonase, 7-bladed beta-propeller DUF2207 PF09972.9 ORY17279.1 - 0.0032 16.3 0.0 0.0038 16.1 0.0 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) Nitrate_red_gam PF02665.14 ORY17279.1 - 0.011 15.3 0.1 0.027 14.0 0.0 1.5 2 0 0 2 2 2 0 Nitrate reductase gamma subunit LamB_YcsF PF03746.16 ORY17281.1 - 1.3e-83 280.3 0.0 1.5e-83 280.2 0.0 1.0 1 0 0 1 1 1 1 LamB/YcsF family CT_A_B PF02626.15 ORY17282.1 - 6.6e-77 258.7 0.0 1.1e-76 258.0 0.0 1.3 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain A and B CPSase_L_D2 PF02786.17 ORY17282.1 - 1.7e-56 191.1 0.0 4.4e-56 189.7 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 ORY17282.1 - 1.2e-39 135.2 0.0 2.5e-39 134.2 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain CT_C_D PF02682.16 ORY17282.1 - 1.1e-33 116.7 0.0 3.3e-33 115.1 0.0 1.8 2 0 0 2 2 2 1 Carboxyltransferase domain, subdomain C and D Biotin_carb_C PF02785.19 ORY17282.1 - 2.9e-31 107.8 0.0 5.7e-31 106.8 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 ORY17282.1 - 8.3e-07 28.8 8.0 0.00015 21.5 2.0 3.4 2 1 1 3 3 3 2 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 ORY17282.1 - 1.1e-06 28.4 0.0 2.2e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.6 ORY17282.1 - 0.001 18.8 1.2 0.032 14.0 0.2 2.8 1 1 1 2 2 2 1 Biotin-lipoyl like ATP-grasp PF02222.22 ORY17282.1 - 0.012 15.2 0.0 0.024 14.2 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain DUF4536 PF15055.6 ORY17283.1 - 0.018 15.3 0.3 0.032 14.5 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4536) ORC6 PF05460.13 ORY17283.1 - 3.4 6.8 9.4 4.3 6.5 9.4 1.0 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) DJ-1_PfpI PF01965.24 ORY17284.1 - 3.1e-09 36.8 0.0 6.8e-09 35.7 0.0 1.6 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 ORY17284.1 - 0.0012 18.6 0.0 0.0016 18.2 0.0 1.2 1 0 0 1 1 1 1 ThiJ/PfpI family-like Aminotran_5 PF00266.19 ORY17285.1 - 4.5e-59 200.3 0.0 6.2e-59 199.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 ORY17285.1 - 6.8e-07 28.2 0.1 2.4e-06 26.4 0.1 1.8 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 ORY17285.1 - 0.0016 17.7 0.0 0.003 16.8 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Glyco_hydro_43 PF04616.14 ORY17286.1 - 5.2e-30 104.7 7.6 7.6e-30 104.2 7.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 ORY17286.1 - 1.1e-25 90.5 0.1 1.9e-25 89.8 0.1 1.4 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain 7TMR-HDED PF07697.11 ORY17287.1 - 0.018 15.2 0.4 0.022 14.9 0.4 1.3 1 0 0 1 1 1 0 7TM-HD extracellular adh_short PF00106.25 ORY17288.1 - 8.5e-33 113.5 1.0 1.9e-32 112.3 1.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY17288.1 - 1.1e-24 87.2 0.3 1.9e-24 86.5 0.3 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY17288.1 - 3.9e-13 49.7 0.2 5.5e-13 49.2 0.2 1.2 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 ORY17288.1 - 4.5e-09 36.2 0.0 6e-09 35.7 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 ORY17288.1 - 1.3e-08 34.7 0.0 1.6e-08 34.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 ORY17288.1 - 8.5e-07 29.0 0.5 1.6e-06 28.1 0.5 1.5 1 1 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 ORY17288.1 - 2e-05 23.9 0.2 3.7e-05 23.0 0.2 1.4 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 ORY17288.1 - 2.8e-05 24.4 0.2 4.7e-05 23.7 0.2 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain RmlD_sub_bind PF04321.17 ORY17288.1 - 0.00062 19.0 0.2 0.0009 18.4 0.2 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.13 ORY17288.1 - 0.0072 15.9 0.4 0.0072 15.9 0.4 1.5 2 0 0 2 2 2 1 NmrA-like family GluRS_N PF18466.1 ORY17288.1 - 0.091 13.2 0.4 2.3 8.7 0.1 2.4 2 0 0 2 2 2 0 Glutamate--tRNA ligase N-terminal domain 3Beta_HSD PF01073.19 ORY17288.1 - 0.16 11.0 0.1 0.22 10.5 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family AAA_12 PF13087.6 ORY17291.1 - 8.9e-10 38.5 0.0 1.1e-09 38.2 0.0 1.1 1 0 0 1 1 1 1 AAA domain DUF3726 PF12525.8 ORY17291.1 - 0.018 15.2 0.0 0.03 14.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3726) UvrD_C_2 PF13538.6 ORY17291.1 - 0.027 14.3 0.0 0.068 13.0 0.0 1.7 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain GST_N_3 PF13417.6 ORY17292.1 - 0.0049 17.2 0.1 0.013 15.9 0.1 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 ORY17292.1 - 0.0059 17.3 0.0 0.021 15.5 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase N-terminal domain GST_C_2 PF13410.6 ORY17292.1 - 0.032 14.3 0.0 0.062 13.3 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 ORY17292.1 - 0.07 13.4 0.0 0.19 12.1 0.0 1.7 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Preseq_ALAS PF09029.10 ORY17293.1 - 0.015 15.7 8.2 0.15 12.5 2.4 2.3 1 1 1 2 2 2 0 5-aminolevulinate synthase presequence DUF4512 PF14975.6 ORY17293.1 - 1.3 9.9 7.3 3.6 8.4 0.3 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4512) MF_alpha_N PF05436.11 ORY17296.1 - 0.24 11.3 2.3 0.39 10.6 1.7 1.7 1 1 0 1 1 1 0 Mating factor alpha precursor N-terminus TauD PF02668.16 ORY17297.1 - 1.8e-36 126.4 0.0 2.7e-36 125.8 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family BET PF17035.5 ORY17299.1 - 0.077 13.2 0.1 0.19 11.9 0.1 1.6 1 0 0 1 1 1 0 Bromodomain extra-terminal - transcription regulation BTB PF00651.31 ORY17299.1 - 0.21 11.8 1.3 6.8 7.0 0.0 2.7 3 0 0 3 3 3 0 BTB/POZ domain Abhydrolase_1 PF00561.20 ORY17301.1 - 1.5e-21 77.2 0.1 1.5e-18 67.4 0.1 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORY17301.1 - 4.1e-15 57.0 2.9 2.7e-14 54.3 2.9 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORY17301.1 - 1.6e-10 40.7 0.0 2.4e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Esterase PF00756.20 ORY17301.1 - 0.0041 16.8 0.1 0.0064 16.2 0.1 1.4 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 ORY17301.1 - 0.019 14.4 0.1 0.063 12.7 0.1 1.8 2 0 0 2 2 2 0 Prolyl oligopeptidase family Antimicrobial14 PF08109.11 ORY17301.1 - 0.078 13.0 0.0 0.21 11.6 0.0 1.8 1 0 0 1 1 1 0 Lactocin 705 family CHB_HEX PF03173.13 ORY17301.1 - 0.12 12.1 0.1 0.23 11.2 0.1 1.4 1 0 0 1 1 1 0 Putative carbohydrate binding domain PsaA_PsaB PF00223.19 ORY17301.1 - 0.13 10.4 1.5 0.55 8.3 0.1 2.0 2 0 0 2 2 2 0 Photosystem I psaA/psaB protein K-cyclin_vir_C PF09080.10 ORY17302.1 - 0.74 10.3 3.1 0.97 9.9 1.8 1.7 1 1 1 2 2 2 0 K cyclin, C terminal BTB PF00651.31 ORY17303.1 - 1.4e-11 44.6 0.0 1.8e-10 41.0 0.0 2.1 2 0 0 2 2 2 1 BTB/POZ domain APOBEC4 PF18775.1 ORY17303.1 - 0.031 14.4 0.0 0.61 10.3 0.0 2.2 1 1 1 2 2 2 0 APOBEC4 Fungal_trans PF04082.18 ORY17304.1 - 1.9e-13 50.1 0.0 3.1e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY17304.1 - 1.5e-06 28.2 8.6 2.6e-06 27.4 8.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pyr_redox_3 PF13738.6 ORY17305.1 - 7.2e-17 61.6 0.0 2e-13 50.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ORY17305.1 - 2.6e-14 53.2 0.0 2.8e-10 39.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 ORY17305.1 - 7.5e-13 47.7 0.0 4.9e-10 38.4 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 ORY17305.1 - 8.5e-08 31.7 0.0 6e-06 25.6 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.12 ORY17305.1 - 2.3e-05 23.6 0.1 0.0035 16.4 0.1 2.6 2 1 0 2 2 2 1 Lycopene cyclase protein Pyr_redox PF00070.27 ORY17305.1 - 8.1e-05 23.1 0.2 0.033 14.7 0.2 2.8 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ORY17305.1 - 0.00011 21.4 0.0 0.0012 18.0 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.6 ORY17305.1 - 0.00034 20.6 0.1 0.27 11.2 0.0 3.1 2 1 0 3 3 3 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 ORY17305.1 - 0.00038 19.8 0.1 0.00078 18.8 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 ORY17305.1 - 0.0006 20.0 0.5 0.0063 16.7 0.0 2.8 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ORY17305.1 - 0.0016 18.1 2.2 0.11 12.1 1.2 2.6 1 1 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 ORY17305.1 - 0.002 16.9 0.0 0.0037 16.0 0.0 1.4 1 0 0 1 1 1 1 HI0933-like protein TrkA_N PF02254.18 ORY17305.1 - 0.0093 16.2 0.2 0.036 14.3 0.1 2.0 2 0 0 2 2 2 1 TrkA-N domain GIDA PF01134.22 ORY17305.1 - 0.044 12.9 0.0 0.3 10.1 0.0 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 ORY17305.1 - 0.066 12.5 0.0 0.17 11.2 0.0 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 ORY17305.1 - 0.077 13.4 0.0 17 5.9 0.0 2.6 2 0 0 2 2 2 0 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.19 ORY17305.1 - 0.09 12.1 0.0 0.48 9.8 0.0 2.0 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ImpE PF07024.13 ORY17306.1 - 0.033 14.3 0.0 0.052 13.6 0.0 1.3 1 0 0 1 1 1 0 ImpE protein CTK3 PF12243.8 ORY17306.1 - 0.093 12.7 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 CTD kinase subunit gamma CTK3 Peptidase_S8 PF00082.22 ORY17307.1 - 4.1e-35 121.5 11.9 7.4e-35 120.7 11.9 1.4 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 ORY17307.1 - 3.2e-18 66.2 0.2 8.5e-18 64.8 0.2 1.8 1 0 0 1 1 1 1 Peptidase inhibitor I9 baeRF_family2 PF18844.1 ORY17307.1 - 0.087 12.9 2.4 0.25 11.4 2.4 1.8 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 2 Beach PF02138.18 ORY17308.1 - 1.3e-118 395.4 0.1 2.6e-118 394.4 0.1 1.5 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 ORY17308.1 - 8.3e-09 35.5 0.0 2.1e-08 34.2 0.0 1.7 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.6 ORY17308.1 - 3.9e-08 33.6 0.0 9.7e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily WD40 PF00400.32 ORY17308.1 - 8.6e-06 26.4 1.4 0.72 10.8 0.0 4.8 5 0 0 5 5 5 2 WD domain, G-beta repeat Flagellin_N PF00669.20 ORY17308.1 - 0.15 12.2 0.8 0.39 10.8 0.8 1.7 1 0 0 1 1 1 0 Bacterial flagellin N-terminal helical region CorA PF01544.18 ORY17310.1 - 2.9e-17 62.9 0.9 6.5e-17 61.8 0.6 1.7 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein DUF676 PF05057.14 ORY17310.1 - 1.9e-05 24.3 0.0 3.4e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) EMP70 PF02990.16 ORY17310.1 - 0.0012 17.6 0.7 0.0018 17.0 0.7 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 PGAP1 PF07819.13 ORY17310.1 - 0.043 13.5 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 PGAP1-like protein Pneumo_matrix PF03393.16 ORY17310.1 - 0.098 11.9 0.1 0.17 11.0 0.1 1.3 1 0 0 1 1 1 0 Pneumovirus matrix protein DUF4891 PF16232.5 ORY17310.1 - 0.13 12.8 0.2 0.28 11.7 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4891) Sulf_transp PF04143.14 ORY17310.1 - 0.18 11.3 0.3 0.28 10.7 0.3 1.2 1 0 0 1 1 1 0 Sulphur transport RRM_2 PF04059.12 ORY17311.1 - 2.9e-05 24.2 0.0 5.9e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif 2 DUF2755 PF10954.8 ORY17315.1 - 0.43 10.5 5.1 0.73 9.8 0.9 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2755) BTB PF00651.31 ORY17316.1 - 3.9e-07 30.3 0.0 2.3e-06 27.8 0.0 2.0 2 0 0 2 2 2 1 BTB/POZ domain Sporozoite_P67 PF05642.11 ORY17316.1 - 0.058 11.5 0.7 0.08 11.0 0.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Rogdi_lz PF10259.9 ORY17316.1 - 0.15 11.5 0.0 0.23 10.9 0.0 1.2 1 0 0 1 1 1 0 Rogdi leucine zipper containing protein MFS_1 PF07690.16 ORY17317.1 - 2e-21 76.3 25.5 2e-21 76.3 25.5 2.6 2 1 1 3 3 3 2 Major Facilitator Superfamily RRM_2 PF04059.12 ORY17318.1 - 5.8e-10 39.3 0.2 5.2e-09 36.2 0.2 1.9 1 1 0 1 1 1 1 RNA recognition motif 2 RRM_1 PF00076.22 ORY17318.1 - 0.034 14.0 0.1 0.65 9.9 0.2 2.1 1 1 1 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glyco_hydro_1 PF00232.18 ORY17322.1 - 8.5e-70 235.4 0.9 8.1e-67 225.6 0.9 2.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 1 OsmC PF02566.19 ORY17323.1 - 4.4e-14 52.8 0.0 8.6e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 OsmC-like protein Prok-RING_4 PF14447.6 ORY17324.1 - 0.0019 18.0 5.3 0.0049 16.7 5.4 1.7 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 ORY17324.1 - 0.0097 15.8 6.0 0.087 12.7 3.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORY17324.1 - 0.13 12.3 6.1 0.35 10.9 6.2 1.7 1 1 0 1 1 1 0 zinc-RING finger domain zf-ANAPC11 PF12861.7 ORY17324.1 - 0.14 12.2 2.4 0.26 11.3 2.4 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 ORY17324.1 - 0.32 10.9 4.1 0.97 9.4 4.1 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORY17324.1 - 0.34 11.3 10.3 2.2 8.7 10.4 2.2 1 1 1 2 2 2 0 Ring finger domain zf-C3HC4_2 PF13923.6 ORY17324.1 - 3.1 7.7 7.9 1.6 8.6 5.2 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 ORY17324.1 - 3.5 7.5 9.4 0.75 9.6 1.7 2.9 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain Pkinase PF00069.25 ORY17325.1 - 2.7e-26 92.5 0.0 3.5e-26 92.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY17325.1 - 5.7e-14 52.0 0.0 1.2e-13 51.0 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORY17325.1 - 0.0065 15.3 0.0 0.01 14.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 ORY17325.1 - 0.047 13.6 2.7 0.44 10.4 0.1 2.8 2 1 1 3 3 3 0 Phosphotransferase enzyme family Glyco_hydro_16 PF00722.21 ORY17332.1 - 7.8e-44 149.2 2.4 1.3e-43 148.6 2.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Peptidase_S10 PF00450.22 ORY17333.1 - 1.8e-77 261.5 0.1 2.2e-77 261.2 0.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase ISET-FN3_linker PF16625.5 ORY17334.1 - 0.0072 16.8 0.1 0.013 16.0 0.1 1.4 1 0 0 1 1 1 1 Unstructured linking region I-set and fnIII on Brother of CDO zf-LITAF-like PF10601.9 ORY17334.1 - 0.0087 16.3 3.2 0.013 15.7 3.2 1.3 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain LPMO_10 PF03067.15 ORY17335.1 - 2.8e-11 44.5 0.6 4.3e-11 43.8 0.6 1.3 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading ABM PF03992.16 ORY17336.1 - 0.0027 17.8 0.0 0.0031 17.6 0.0 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase FemAB_like PF04339.12 ORY17336.1 - 0.093 11.8 0.0 0.11 11.7 0.0 1.0 1 0 0 1 1 1 0 Peptidogalycan biosysnthesis/recognition ABM PF03992.16 ORY17337.1 - 0.00035 20.6 0.0 0.00048 20.2 0.0 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase DUF4937 PF16291.5 ORY17337.1 - 0.019 15.2 0.0 0.022 15.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4937 p450 PF00067.22 ORY17338.1 - 1.4e-70 238.3 0.0 1.9e-70 237.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ORC_WH_C PF18137.1 ORY17338.1 - 0.17 12.0 0.0 0.51 10.4 0.0 1.7 2 0 0 2 2 2 0 Origin recognition complex winged helix C-terminal Alpha_TIF PF02232.15 ORY17338.1 - 0.17 11.0 0.0 0.26 10.3 0.0 1.2 1 0 0 1 1 1 0 Alpha trans-inducing protein (Alpha-TIF) MaoC_dehydratas PF01575.19 ORY17340.1 - 2.6e-25 88.4 0.0 5.5e-25 87.3 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 ORY17340.1 - 5.6e-07 29.8 0.1 0.046 13.9 0.0 2.4 2 1 0 2 2 2 2 N-terminal half of MaoC dehydratase AMP-binding PF00501.28 ORY17341.1 - 1.4e-63 214.9 0.0 2.3e-44 151.6 0.0 2.1 1 1 1 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 ORY17341.1 - 1.8e-07 32.0 0.1 3.9e-07 30.9 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Glyco_hydro2_C5 PF18565.1 ORY17341.1 - 0.068 13.0 0.1 0.14 12.0 0.1 1.4 1 0 0 1 1 1 0 Glycoside hydrolase family 2 C-terminal domain 5 HET PF06985.11 ORY17342.1 - 5.3e-25 88.5 2.3 1.1e-23 84.2 0.3 2.5 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) Methyltransf_23 PF13489.6 ORY17343.1 - 2.9e-20 72.8 0.0 4e-20 72.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY17343.1 - 1.6e-09 38.3 0.0 3.8e-09 37.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY17343.1 - 9.3e-08 32.6 0.0 1.9e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY17343.1 - 4.1e-07 30.7 0.0 2.3e-06 28.3 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY17343.1 - 7.7e-06 25.8 0.0 0.015 15.1 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain MTS PF05175.14 ORY17343.1 - 0.0062 16.1 0.0 0.07 12.7 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_16 PF10294.9 ORY17343.1 - 0.0077 16.0 0.0 0.013 15.3 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 ORY17343.1 - 0.028 13.8 0.0 0.043 13.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.17 ORY17343.1 - 0.13 11.7 0.0 0.39 10.2 0.0 1.7 1 0 0 1 1 1 0 Putative methyltransferase p450 PF00067.22 ORY17344.1 - 4.3e-38 131.3 0.0 5.8e-19 68.2 0.1 2.1 2 0 0 2 2 2 2 Cytochrome P450 YEATS PF03366.16 ORY17345.1 - 6.6e-27 93.3 0.1 1.2e-26 92.5 0.1 1.4 1 0 0 1 1 1 1 YEATS family SPATA1_C PF15743.5 ORY17345.1 - 0.0014 18.8 0.3 0.0014 18.8 0.3 1.5 2 0 0 2 2 2 1 Spermatogenesis-associated C-terminus Epimerase PF01370.21 ORY17346.1 - 1e-06 28.4 0.0 2.7e-06 27.0 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 ORY17346.1 - 1.4e-05 25.1 0.0 3.1e-05 24.0 0.0 1.8 1 1 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 ORY17346.1 - 4.7e-05 22.5 0.0 8.2e-05 21.7 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 ORY17346.1 - 0.00084 18.8 0.0 0.0012 18.3 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 ORY17346.1 - 0.0035 16.5 0.0 0.013 14.7 0.0 1.8 2 0 0 2 2 2 1 RmlD substrate binding domain adh_short PF00106.25 ORY17346.1 - 0.069 12.6 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase 3HCDH_N PF02737.18 ORY17346.1 - 0.18 11.7 0.0 2.9 7.7 0.0 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NmrA PF05368.13 ORY17346.1 - 0.2 11.2 0.0 0.61 9.6 0.0 1.8 2 0 0 2 2 2 0 NmrA-like family SfsA_N PF17746.1 ORY17349.1 - 0.0069 16.5 0.0 0.11 12.7 0.0 2.1 2 0 0 2 2 2 1 SfsA N-terminal OB domain DUF2001 PF09393.10 ORY17349.1 - 0.2 11.6 0.0 7.3 6.6 0.0 2.1 2 0 0 2 2 2 0 Phage tail tube protein K-cyclin_vir_C PF09080.10 ORY17351.1 - 0.19 12.2 1.3 0.32 11.4 1.3 1.3 1 0 0 1 1 1 0 K cyclin, C terminal Homeobox_KN PF05920.11 ORY17352.1 - 1.2e-17 63.5 0.5 5.1e-17 61.5 0.5 2.2 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 ORY17352.1 - 9e-09 35.1 0.4 1.7e-08 34.2 0.4 1.4 1 0 0 1 1 1 1 Homeodomain Abhydrolase_1 PF00561.20 ORY17353.1 - 9.8e-24 84.4 1.7 1.5e-23 83.8 0.1 2.1 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 ORY17353.1 - 4.7e-20 70.9 0.1 1.1e-19 69.8 0.1 1.7 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Hydrolase_4 PF12146.8 ORY17353.1 - 8.5e-06 25.2 0.0 0.0051 16.1 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 FSH1 PF03959.13 ORY17353.1 - 0.0002 21.1 0.5 0.11 12.2 0.0 2.5 3 0 0 3 3 3 2 Serine hydrolase (FSH1) Pet191_N PF10203.9 ORY17354.1 - 1.9e-26 92.2 4.2 2.4e-26 91.8 4.2 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.10 ORY17354.1 - 0.017 15.1 1.9 0.37 10.8 0.0 2.3 2 0 0 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like RST PF12174.8 ORY17354.1 - 0.14 12.1 0.1 0.28 11.1 0.0 1.5 2 0 0 2 2 2 0 RCD1-SRO-TAF4 (RST) plant domain CX9C PF16860.5 ORY17354.1 - 1.8 8.6 9.6 4.8 7.3 0.3 2.8 1 1 2 3 3 3 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, DHFR_2 PF06442.11 ORY17355.1 - 0.34 10.8 0.1 0.34 10.8 0.1 1.7 2 0 0 2 2 2 0 R67 dihydrofolate reductase Fungal_trans_2 PF11951.8 ORY17390.1 - 1.4e-39 136.0 0.1 1.8e-39 135.7 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY17390.1 - 4.1e-07 30.0 9.5 6.4e-07 29.4 9.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ECH_1 PF00378.20 ORY17391.1 - 2.5e-32 112.2 0.0 5e-32 111.2 0.0 1.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ORY17391.1 - 1.5e-14 54.3 0.0 1.8e-14 54.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Asp PF00026.23 ORY17393.1 - 2.8e-13 50.0 0.2 3.2e-08 33.3 0.0 2.1 2 0 0 2 2 2 2 Eukaryotic aspartyl protease VSP PF03302.13 ORY17393.1 - 0.00079 18.4 0.7 0.0015 17.5 0.7 1.3 1 0 0 1 1 1 1 Giardia variant-specific surface protein SKG6 PF08693.10 ORY17393.1 - 0.001 18.4 4.0 0.001 18.4 4.0 1.9 2 0 0 2 2 2 1 Transmembrane alpha-helix domain EphA2_TM PF14575.6 ORY17393.1 - 0.0019 19.0 0.0 0.0042 17.9 0.0 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Syndecan PF01034.20 ORY17393.1 - 0.015 15.2 0.0 0.015 15.2 0.0 2.0 2 0 0 2 2 2 0 Syndecan domain FeoB_associated PF12669.7 ORY17393.1 - 0.039 14.4 0.3 0.078 13.4 0.3 1.4 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein TAXi_N PF14543.6 ORY17393.1 - 0.049 13.9 0.1 0.11 12.8 0.1 1.5 1 0 0 1 1 1 0 Xylanase inhibitor N-terminal TraL PF07178.11 ORY17393.1 - 0.11 13.0 0.2 0.36 11.3 0.2 1.9 1 0 0 1 1 1 0 TraL protein DAP10 PF07213.11 ORY17393.1 - 0.12 12.3 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 DAP10 membrane protein CN_hydrolase PF00795.22 ORY17395.1 - 1.8e-40 139.0 0.0 2.4e-40 138.5 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Fungal_trans PF04082.18 ORY17396.1 - 2.9e-19 69.2 1.6 4.7e-19 68.4 1.6 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY17396.1 - 6e-05 23.1 9.9 0.00018 21.5 9.9 1.9 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Transp_cyt_pur PF02133.15 ORY17397.1 - 1.6e-97 327.1 36.2 1.8e-97 326.9 36.2 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Amidohydro_1 PF01979.20 ORY17398.1 - 3.3e-27 95.7 0.0 4.6e-27 95.2 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 ORY17398.1 - 3.7e-15 56.4 0.2 5.4e-06 26.1 0.0 2.9 3 0 0 3 3 3 2 Amidohydrolase family Urease_alpha PF00449.20 ORY17398.1 - 0.076 13.3 0.3 0.16 12.3 0.3 1.6 1 0 0 1 1 1 0 Urease alpha-subunit, N-terminal domain CENP-Q PF13094.6 ORY17399.1 - 0.075 13.2 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF4824 PF16106.5 ORY17400.1 - 0.14 11.4 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4824) Flavin_Reduct PF01613.18 ORY17401.1 - 2.8e-14 53.4 0.0 4.1e-14 52.9 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain adh_short PF00106.25 ORY17402.1 - 5.4e-18 65.2 0.0 1e-17 64.2 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY17402.1 - 5.1e-08 32.8 0.0 7.2e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Neogenin_C PF06583.12 ORY17404.1 - 0.066 13.0 0.9 0.084 12.7 0.9 1.1 1 0 0 1 1 1 0 Neogenin C-terminus Helo_like_N PF17111.5 ORY17406.1 - 1.2e-07 31.4 0.1 1.4e-07 31.1 0.1 1.1 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins TBCC_N PF16752.5 ORY17406.1 - 0.06 13.8 0.8 0.44 11.0 0.4 2.0 2 0 0 2 2 2 0 Tubulin-specific chaperone C N-terminal domain GSCFA PF08885.11 ORY17406.1 - 0.061 13.0 0.0 0.11 12.1 0.0 1.3 1 1 0 1 1 1 0 GSCFA family PH PF00169.29 ORY17407.1 - 4.7e-07 30.3 0.0 1.8e-06 28.4 0.0 1.9 1 1 0 1 1 1 1 PH domain PH_9 PF15410.6 ORY17407.1 - 0.0076 16.6 0.0 0.22 11.9 0.0 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain Patatin PF01734.22 ORY17408.1 - 0.039 14.1 0.5 0.051 13.8 0.5 1.1 1 0 0 1 1 1 0 Patatin-like phospholipase Crystall PF00030.19 ORY17409.1 - 0.036 14.3 0.2 0.06 13.5 0.2 1.4 1 1 0 1 1 1 0 Beta/Gamma crystallin FGGY_C PF02782.16 ORY17410.1 - 8.5e-30 104.0 0.0 1.3e-29 103.4 0.0 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 ORY17410.1 - 8.6e-15 55.0 0.0 2.9e-09 36.8 0.0 2.5 2 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain Cation_efflux PF01545.21 ORY17411.1 - 4.3e-41 140.9 0.8 7e-41 140.1 0.8 1.3 1 1 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 ORY17411.1 - 6.3e-05 23.0 0.0 0.00012 22.2 0.0 1.5 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter Hydrolase_4 PF12146.8 ORY17412.1 - 1.9e-50 171.4 0.0 2.2e-50 171.2 0.0 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ORY17412.1 - 8.9e-12 46.1 0.0 1.1e-11 45.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ORY17412.1 - 7.7e-08 32.3 0.0 1.5e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF1749 PF08538.10 ORY17412.1 - 0.0014 17.8 0.0 0.0031 16.7 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1749) ATG101 PF07855.12 ORY17412.1 - 0.095 12.7 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Autophagy-related protein 101 PGAP1 PF07819.13 ORY17412.1 - 0.098 12.4 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Peptidase_S9 PF00326.21 ORY17412.1 - 0.12 11.8 0.0 14 5.0 0.0 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family NAD_binding_1 PF00175.21 ORY17413.1 - 4.4e-08 33.7 0.0 0.0035 18.0 0.0 2.4 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 ORY17413.1 - 0.0001 22.5 0.0 0.002 18.3 0.0 2.3 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_6 PF00970.24 ORY17413.1 - 0.0022 18.3 0.0 0.0073 16.6 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain PAF-AH_p_II PF03403.13 ORY17414.1 - 2e-13 49.6 0.1 1.7e-11 43.2 0.0 2.2 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Hydrolase_4 PF12146.8 ORY17414.1 - 4.5e-05 22.8 0.1 0.033 13.5 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 ORY17414.1 - 7e-05 21.9 0.0 0.00017 20.6 0.0 1.5 1 1 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 ORY17414.1 - 0.0078 15.3 0.1 0.08 11.9 0.0 2.0 1 1 1 2 2 2 1 Chlorophyllase Abhydrolase_6 PF12697.7 ORY17414.1 - 0.012 16.3 1.0 0.018 15.6 1.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF2106 PF09879.9 ORY17414.1 - 0.012 15.2 0.1 0.02 14.4 0.1 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2106) Abhydrolase_5 PF12695.7 ORY17414.1 - 0.021 14.6 0.6 0.6 9.9 0.1 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase family Thioesterase PF00975.20 ORY17414.1 - 0.81 9.8 2.4 2.4 8.2 0.9 2.1 2 0 0 2 2 2 0 Thioesterase domain MARVEL PF01284.23 ORY17416.1 - 6.2e-05 23.0 7.3 0.00012 22.1 7.3 1.5 1 1 0 1 1 1 1 Membrane-associating domain PRA1 PF03208.19 ORY17416.1 - 0.008 15.8 2.4 0.016 14.9 2.4 1.5 1 1 0 1 1 1 1 PRA1 family protein HemY_N PF07219.13 ORY17416.1 - 0.025 14.8 3.6 0.31 11.3 0.0 2.5 2 0 0 2 2 2 0 HemY protein N-terminus Rer1 PF03248.13 ORY17416.1 - 0.1 12.3 5.4 12 5.6 4.6 2.3 2 0 0 2 2 2 0 Rer1 family SieB PF14163.6 ORY17416.1 - 0.11 12.0 2.4 0.99 8.9 0.0 2.2 2 0 0 2 2 2 0 Super-infection exclusion protein B FAM176 PF14851.6 ORY17416.1 - 0.12 12.0 0.1 0.23 11.1 0.0 1.4 2 0 0 2 2 2 0 FAM176 family OAD_gamma PF04277.13 ORY17416.1 - 0.23 12.0 0.1 0.23 12.0 0.1 1.9 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain FixQ PF05545.11 ORY17416.1 - 4.6 7.3 7.8 1 9.4 0.3 2.8 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ adh_short PF00106.25 ORY17417.1 - 3.6e-38 131.0 0.0 4.7e-38 130.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY17417.1 - 5e-26 91.7 0.0 7.4e-26 91.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY17417.1 - 5.9e-05 23.1 0.0 0.00013 21.9 0.0 1.6 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 ORY17417.1 - 0.0006 19.7 0.5 0.0012 18.8 0.0 1.8 3 0 0 3 3 3 1 NAD(P)H-binding HLH PF00010.26 ORY17418.1 - 3.3e-14 52.6 0.1 6.7e-14 51.6 0.1 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain FAM76 PF16046.5 ORY17418.1 - 0.012 15.0 6.0 0.026 13.9 6.0 1.5 1 0 0 1 1 1 0 FAM76 protein Med28 PF11594.8 ORY17418.1 - 0.018 15.1 2.1 0.024 14.7 0.6 2.0 2 1 0 2 2 2 0 Mediator complex subunit 28 USP8_interact PF08941.10 ORY17418.1 - 0.19 11.5 1.1 0.37 10.6 1.1 1.4 1 0 0 1 1 1 0 USP8 interacting ATG16 PF08614.11 ORY17418.1 - 6.6 6.9 14.8 0.041 14.1 1.3 2.9 3 0 0 3 3 3 0 Autophagy protein 16 (ATG16) G-gamma PF00631.22 ORY17419.1 - 9.6e-21 73.6 0.0 1.1e-20 73.4 0.0 1.1 1 0 0 1 1 1 1 GGL domain PCI PF01399.27 ORY17420.1 - 2.2e-08 34.5 2.3 1.6e-07 31.7 0.0 3.2 3 0 0 3 3 3 1 PCI domain UBM PF14377.6 ORY17421.1 - 0.0087 15.5 0.1 0.019 14.4 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin binding region Sugar_tr PF00083.24 ORY17422.1 - 1.4e-85 287.9 16.8 1.7e-85 287.6 16.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY17422.1 - 1.5e-34 119.5 15.5 1.5e-34 119.5 15.5 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3792 PF12670.7 ORY17422.1 - 0.0048 17.1 4.0 0.0048 17.1 4.0 3.4 4 0 0 4 4 4 2 Protein of unknown function (DUF3792) Lipase_3 PF01764.25 ORY17424.1 - 6.4e-35 120.1 0.0 1.1e-34 119.3 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Lipase3_N PF03893.16 ORY17424.1 - 3.7e-09 36.5 0.1 7.3e-09 35.5 0.1 1.4 1 0 0 1 1 1 1 Lipase 3 N-terminal region Hydrolase_4 PF12146.8 ORY17424.1 - 7.5e-05 22.1 0.0 0.00011 21.5 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF2974 PF11187.8 ORY17424.1 - 0.00068 19.3 0.4 0.0018 17.9 0.4 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.7 ORY17424.1 - 0.0017 19.0 0.0 0.0021 18.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Cutinase PF01083.22 ORY17424.1 - 0.0045 17.0 0.1 0.01 15.8 0.1 1.6 1 1 0 1 1 1 1 Cutinase PGAP1 PF07819.13 ORY17424.1 - 0.039 13.7 0.0 0.086 12.6 0.0 1.4 1 1 0 1 1 1 0 PGAP1-like protein DUF676 PF05057.14 ORY17424.1 - 0.039 13.5 0.0 0.059 12.9 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.7 ORY17424.1 - 0.077 12.8 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Thioesterase PF00975.20 ORY17424.1 - 0.11 12.6 0.1 0.19 11.8 0.1 1.3 1 0 0 1 1 1 0 Thioesterase domain Rdx PF10262.9 ORY17425.1 - 1.6e-19 69.8 0.0 2.6e-19 69.2 0.0 1.2 1 0 0 1 1 1 1 Rdx family FlgN PF05130.12 ORY17426.1 - 0.027 15.0 2.0 2.2 8.8 0.1 2.4 2 1 0 2 2 2 0 FlgN protein RILP PF11461.8 ORY17426.1 - 0.057 13.7 0.4 0.14 12.4 0.2 1.8 2 0 0 2 2 2 0 Rab interacting lysosomal protein SAGA-Tad1 PF12767.7 ORY17426.1 - 0.12 12.1 0.6 3.8 7.2 0.1 2.2 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit GARP PF16731.5 ORY17426.1 - 0.19 11.4 3.1 0.24 11.1 0.4 2.4 2 0 0 2 2 2 0 Glutamic acid/alanine-rich protein of Trypanosoma DUF1664 PF07889.12 ORY17426.1 - 2.3 8.3 6.4 1.6 8.8 1.4 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) MMR_HSR1 PF01926.23 ORY17427.1 - 4e-08 33.3 0.0 6.8e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ORY17427.1 - 2.9e-05 24.0 0.0 0.00039 20.4 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 ORY17427.1 - 0.0024 18.3 0.1 0.006 17.0 0.1 1.6 1 0 0 1 1 1 1 AAA ATPase domain AIG1 PF04548.16 ORY17427.1 - 0.0029 16.9 0.0 0.0041 16.5 0.0 1.2 1 0 0 1 1 1 1 AIG1 family AAA_22 PF13401.6 ORY17427.1 - 0.0043 17.3 0.0 0.0088 16.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 ORY17427.1 - 0.026 13.7 0.0 0.05 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ABC_tran PF00005.27 ORY17427.1 - 0.04 14.4 0.0 0.11 13.1 0.0 1.7 1 0 0 1 1 1 0 ABC transporter Dynamin_N PF00350.23 ORY17427.1 - 0.049 13.7 0.1 1.2 9.2 0.1 2.3 1 1 1 2 2 2 0 Dynamin family AAA_18 PF13238.6 ORY17427.1 - 0.099 13.2 0.0 0.21 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 ORY17427.1 - 0.12 12.1 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 ORY17427.1 - 0.16 11.7 0.1 0.37 10.6 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain NACHT PF05729.12 ORY17427.1 - 0.21 11.5 0.1 1.2 9.0 0.1 2.0 2 0 0 2 2 2 0 NACHT domain Pex14_N PF04695.13 ORY17427.1 - 2.3 8.9 6.1 3.9 8.1 6.1 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region MAT1 PF06391.13 ORY17428.1 - 1.2e-34 120.0 5.2 1.5e-34 119.6 5.2 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_5 PF17121.5 ORY17428.1 - 6.7e-30 102.7 8.6 1.1e-29 102.0 8.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORY17428.1 - 0.00028 20.7 3.2 0.00066 19.5 3.2 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 ORY17428.1 - 0.00033 20.5 5.6 0.00056 19.7 5.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 ORY17428.1 - 0.0004 20.2 4.9 0.0014 18.4 5.3 1.7 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORY17428.1 - 0.0028 18.0 6.9 0.0048 17.2 6.9 1.4 1 0 0 1 1 1 1 Ring finger domain DUF3797 PF12677.7 ORY17428.1 - 0.018 14.9 2.2 0.04 13.8 2.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3797) zf-RING_4 PF14570.6 ORY17428.1 - 0.021 14.6 6.5 0.13 12.1 3.0 2.4 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.6 ORY17428.1 - 0.042 13.8 8.6 0.41 10.6 9.5 2.0 1 1 1 2 2 2 0 zinc-RING finger domain Zn_ribbon_17 PF17120.5 ORY17428.1 - 0.056 13.1 2.1 0.11 12.2 2.1 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 ORY17428.1 - 0.2 11.7 6.2 0.36 10.9 6.2 1.4 1 0 0 1 1 1 0 RING-type zinc-finger Prok-RING_4 PF14447.6 ORY17428.1 - 0.52 10.2 7.6 6.3 6.7 8.2 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Prefoldin_3 PF13758.6 ORY17429.1 - 1.6e-32 111.5 1.5 4e-32 110.2 1.5 1.7 1 0 0 1 1 1 1 Prefoldin subunit DUF3835 PF12927.7 ORY17429.1 - 2.8e-25 88.9 0.1 2.8e-25 88.9 0.1 5.0 5 1 0 5 5 5 2 Domain of unknown function (DUF3835) NPV_P10 PF05531.12 ORY17429.1 - 0.041 14.3 0.5 0.16 12.5 0.5 2.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein CoA_binding_2 PF13380.6 ORY17429.1 - 0.11 13.0 0.2 1 9.9 0.2 2.4 1 1 0 1 1 1 0 CoA binding domain FAA_hydro_N_2 PF18288.1 ORY17429.1 - 0.33 11.4 2.9 1.1 9.8 0.5 2.7 3 0 0 3 3 3 0 Fumarylacetoacetase N-terminal domain 2 Pilin_N PF07790.11 ORY17430.1 - 0.002 19.0 0.8 0.0041 18.0 0.6 1.7 1 1 0 1 1 1 1 Archaeal Type IV pilin, N-terminal PAP1 PF08601.10 ORY17430.1 - 0.43 10.3 12.6 0.64 9.7 12.6 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 OATP PF03137.20 ORY17430.1 - 0.69 8.1 7.5 1.9 6.7 0.5 2.0 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Hamartin PF04388.12 ORY17430.1 - 4.8 5.7 5.4 5.7 5.5 5.4 1.1 1 0 0 1 1 1 0 Hamartin protein DUF3176 PF11374.8 ORY17431.1 - 2.2e-29 101.8 1.6 1.4e-28 99.2 0.5 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) DUF5326 PF17260.2 ORY17431.1 - 0.086 13.0 4.0 0.45 10.7 0.9 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5326) MARVEL PF01284.23 ORY17432.1 - 4.2e-09 36.6 5.0 5.5e-09 36.2 5.0 1.3 1 0 0 1 1 1 1 Membrane-associating domain DUF2933 PF11666.8 ORY17432.1 - 0.0076 16.3 1.5 0.018 15.0 1.5 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2933) DUF1129 PF06570.11 ORY17432.1 - 0.77 9.2 2.2 1.2 8.5 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) Putative_PNPOx PF01243.20 ORY17433.1 - 1.1e-10 41.5 0.0 9.9e-07 28.9 0.0 2.7 3 0 0 3 3 3 2 Pyridoxamine 5'-phosphate oxidase FAD_binding_6 PF00970.24 ORY17433.1 - 0.01 16.2 0.0 0.8 10.1 0.0 2.7 1 1 0 1 1 1 0 Oxidoreductase FAD-binding domain GREB1 PF15782.5 ORY17434.1 - 0.00064 17.0 4.8 0.00072 16.8 4.8 1.0 1 0 0 1 1 1 1 Gene regulated by oestrogen in breast cancer eIF3_subunit PF08597.10 ORY17434.1 - 0.0014 18.6 25.0 0.0025 17.8 25.0 1.3 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit GAGA_bind PF06217.12 ORY17434.1 - 0.002 18.5 10.7 0.0022 18.4 10.7 1.3 1 0 0 1 1 1 1 GAGA binding protein-like family eIF-3_zeta PF05091.12 ORY17434.1 - 0.013 14.6 12.1 0.015 14.3 12.1 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) SET PF00856.28 ORY17434.1 - 0.032 14.6 0.8 0.037 14.4 0.8 1.3 1 0 0 1 1 1 0 SET domain DUF3807 PF12720.7 ORY17434.1 - 0.047 14.0 18.8 0.077 13.3 18.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) DDHD PF02862.17 ORY17434.1 - 0.05 13.7 3.0 0.061 13.5 3.0 1.3 1 0 0 1 1 1 0 DDHD domain Coilin_N PF15862.5 ORY17434.1 - 0.063 13.1 19.7 0.31 10.9 19.7 2.2 1 1 0 1 1 1 0 Coilin N-terminus Vfa1 PF08432.10 ORY17434.1 - 0.073 13.4 20.2 0.12 12.7 20.2 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 AAA_11 PF13086.6 ORY17434.1 - 0.091 12.5 10.2 0.13 12.0 10.2 1.3 1 0 0 1 1 1 0 AAA domain EOS1 PF12326.8 ORY17434.1 - 0.092 12.7 4.5 0.11 12.4 4.5 1.4 1 0 0 1 1 1 0 N-glycosylation protein CDC45 PF02724.14 ORY17434.1 - 0.23 9.7 20.7 0.38 9.0 19.3 1.8 2 0 0 2 2 2 0 CDC45-like protein VSG_B PF13206.6 ORY17434.1 - 0.23 10.7 11.1 0.3 10.3 11.1 1.2 1 0 0 1 1 1 0 Trypanosomal VSG domain DUF4569 PF15133.6 ORY17434.1 - 0.4 10.4 5.3 0.58 9.8 5.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) IHO1 PF15771.5 ORY17434.1 - 0.41 9.4 16.3 0.63 8.7 16.3 1.3 1 0 0 1 1 1 0 Interactor of HORMAD1 protein 1 Neur_chan_memb PF02932.16 ORY17434.1 - 0.56 10.2 3.9 0.57 10.2 3.9 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF1764 PF08576.10 ORY17434.1 - 0.57 11.1 25.5 1.3 10.0 25.5 1.6 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) RNA_polI_A34 PF08208.11 ORY17434.1 - 0.62 10.1 34.0 1.1 9.2 34.0 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 DUF4776 PF16003.5 ORY17434.1 - 0.74 8.7 21.1 0.99 8.3 21.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) DUF2151 PF10221.9 ORY17434.1 - 0.84 8.2 11.7 1.2 7.7 11.7 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator ALMT PF11744.8 ORY17434.1 - 0.93 8.2 8.1 1.4 7.7 8.1 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Zip PF02535.22 ORY17434.1 - 1.1 8.4 2.5 1.3 8.1 2.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF4228 PF14009.6 ORY17434.1 - 1.2 9.5 12.4 2.2 8.6 12.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) DUF4614 PF15391.6 ORY17434.1 - 3 7.8 10.4 5.5 7.0 10.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Ctr PF04145.15 ORY17434.1 - 3.1 8.4 5.3 4.8 7.8 5.3 1.4 1 0 0 1 1 1 0 Ctr copper transporter family RNA_pol_Rpc4 PF05132.14 ORY17434.1 - 3.4 8.1 12.3 5.6 7.4 12.3 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF5427 PF10310.9 ORY17434.1 - 4.6 6.1 16.0 6.7 5.5 16.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Presenilin PF01080.17 ORY17434.1 - 5 5.8 12.6 6.8 5.4 12.6 1.1 1 0 0 1 1 1 0 Presenilin NPR3 PF03666.13 ORY17434.1 - 5.1 5.8 19.7 8.9 5.0 19.7 1.4 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Connexin PF00029.19 ORY17434.1 - 6.1 6.5 16.7 8.9 6.0 16.7 1.2 1 0 0 1 1 1 0 Connexin Sec62 PF03839.16 ORY17434.1 - 6.7 6.1 19.3 11 5.4 19.3 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 OATP PF03137.20 ORY17434.1 - 8.4 4.5 7.4 10 4.2 7.4 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF4770 PF15994.5 ORY17434.1 - 8.6 6.6 18.5 14 5.8 18.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) MFS_1 PF07690.16 ORY17435.1 - 2.6e-42 145.0 55.1 2.6e-42 145.0 55.1 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 ORY17435.1 - 1.6e-14 53.3 29.5 2.3e-14 52.8 29.5 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Tim17 PF02466.19 ORY17436.1 - 5.2e-29 100.9 9.0 7.6e-29 100.3 9.0 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family PAS PF00989.25 ORY17438.1 - 3.7e-05 23.7 0.0 0.00011 22.2 0.0 1.7 2 0 0 2 2 2 1 PAS fold Zn_clus PF00172.18 ORY17438.1 - 0.0059 16.7 8.6 0.01 15.9 8.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 ORY17439.1 - 5.9e-31 107.7 27.7 1e-30 106.9 27.7 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 ORY17439.1 - 1.4e-10 40.2 2.4 2.6e-10 39.3 2.4 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 ORY17439.1 - 2.9e-10 39.6 2.8 4.7e-10 38.9 2.8 1.4 1 0 0 1 1 1 1 Sugar (and other) transporter Glyco_transf_22 PF03901.17 ORY17439.1 - 0.0092 15.3 6.7 0.085 12.1 0.1 2.4 2 0 0 2 2 2 2 Alg9-like mannosyltransferase family NAD_binding_8 PF13450.6 ORY17440.1 - 1.6e-09 37.9 1.9 2.9e-09 37.0 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 ORY17440.1 - 3e-09 36.7 0.0 4.2e-06 26.3 0.0 2.3 1 1 0 2 2 2 2 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 ORY17440.1 - 8.8e-07 28.6 0.0 2.3e-06 27.3 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO PF01266.24 ORY17440.1 - 2.5e-06 27.3 0.1 0.0074 15.9 0.3 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 ORY17440.1 - 4e-06 26.2 0.2 6e-06 25.6 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 ORY17440.1 - 1.7e-05 23.7 0.2 3e-05 22.9 0.2 1.4 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.19 ORY17440.1 - 0.00056 19.2 0.1 0.00093 18.5 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 ORY17440.1 - 0.00063 19.1 0.3 0.0026 17.1 0.3 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ORY17440.1 - 0.0014 17.9 0.0 0.0043 16.3 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORY17440.1 - 0.0086 16.6 0.1 0.043 14.4 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 ORY17440.1 - 0.019 14.2 0.1 0.035 13.4 0.1 1.4 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.22 ORY17440.1 - 0.055 12.5 0.1 0.078 12.0 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A IlvN PF07991.12 ORY17440.1 - 0.12 11.9 0.2 0.23 11.0 0.2 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain SARS_3b PF12383.8 ORY17440.1 - 0.13 12.3 0.1 0.27 11.3 0.1 1.5 1 0 0 1 1 1 0 Severe acute respiratory syndrome coronavirus 3b protein FF PF01846.19 ORY17441.1 - 3.8e-14 52.6 0.2 3.8e-14 52.6 0.2 3.0 3 0 0 3 3 3 2 FF domain WW PF00397.26 ORY17441.1 - 3.1e-09 36.7 3.7 1.5e-07 31.3 1.0 2.5 2 0 0 2 2 2 2 WW domain Hid1 PF12722.7 ORY17441.1 - 5.3 5.0 5.6 8.8 4.3 5.6 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Proteasome PF00227.26 ORY17442.1 - 1.2e-60 204.3 0.0 1.5e-60 204.0 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 ORY17442.1 - 4.4e-13 48.6 0.1 8.7e-13 47.7 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF5624 PF18538.1 ORY17442.1 - 0.012 15.7 0.1 0.032 14.4 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5624) Nitrate_red_gam PF02665.14 ORY17442.1 - 0.018 14.6 0.0 0.026 14.1 0.0 1.1 1 0 0 1 1 1 0 Nitrate reductase gamma subunit APC_u5 PF16630.5 ORY17443.1 - 0.77 10.8 0.0 0.77 10.8 0.0 2.5 3 0 0 3 3 3 0 Unstructured region on APC between 1st and 2nd catenin-bdg motifs Peptidase_S64 PF08192.11 ORY17444.1 - 2.2 6.7 4.7 2.3 6.6 4.7 1.0 1 0 0 1 1 1 0 Peptidase family S64 Atx10homo_assoc PF09759.9 ORY17446.1 - 2e-29 101.5 2.9 1.3e-27 95.7 0.1 2.9 2 1 1 3 3 3 2 Spinocerebellar ataxia type 10 protein domain HMG_box_2 PF09011.10 ORY17446.1 - 0.0023 18.5 0.1 0.0076 16.8 0.1 1.8 1 0 0 1 1 1 1 HMG-box domain HMG_box PF00505.19 ORY17446.1 - 0.0032 17.9 0.1 0.0079 16.6 0.1 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box AATF-Che1 PF13339.6 ORY17446.1 - 0.013 16.1 0.3 12 6.6 0.0 3.0 3 0 0 3 3 3 0 Apoptosis antagonizing transcription factor COG5 PF10392.9 ORY17446.1 - 0.047 13.9 0.1 0.22 11.7 0.0 2.1 2 0 0 2 2 2 0 Golgi transport complex subunit 5 DUF3176 PF11374.8 ORY17447.1 - 2.3e-34 117.8 0.7 2.3e-34 117.8 0.7 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) DUF3153 PF11353.8 ORY17447.1 - 0.039 13.5 1.9 1.6 8.3 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3153) 5HT_transport_N PF03491.13 ORY17448.1 - 1.7e-07 31.3 30.1 5.7 7.2 0.1 7.5 8 0 0 8 8 8 7 Serotonin (5-HT) neurotransmitter transporter, N-terminus AvrPtoB_bdg PF16847.5 ORY17448.1 - 0.38 11.3 2.5 59 4.2 0.0 4.3 1 1 5 6 6 6 0 Avirulence AvrPtoB, BAK1-binding domain SPOC PF07744.13 ORY17449.1 - 8.8e-20 71.2 0.0 1.7e-19 70.3 0.0 1.5 1 0 0 1 1 1 1 SPOC domain TFIIS_M PF07500.14 ORY17449.1 - 2e-17 63.7 0.1 4e-17 62.7 0.1 1.5 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain PHD PF00628.29 ORY17449.1 - 6.3e-09 35.6 13.1 1.1e-08 34.8 13.1 1.4 1 0 0 1 1 1 1 PHD-finger Atg14 PF10186.9 ORY17450.1 - 0.14 11.2 1.3 0.19 10.7 1.3 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF724 PF05266.14 ORY17450.1 - 0.93 9.3 8.3 1.5 8.6 8.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) ArfGap PF01412.18 ORY17451.1 - 5.9e-41 139.2 0.8 8.5e-41 138.7 0.8 1.2 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf DUF4349 PF14257.6 ORY17452.1 - 0.075 12.5 0.0 0.091 12.2 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) adh_short_C2 PF13561.6 ORY17453.1 - 7.6e-66 222.0 0.7 9.1e-66 221.8 0.7 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY17453.1 - 4.9e-51 173.0 0.4 6.8e-51 172.5 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORY17453.1 - 8.5e-11 42.1 0.1 1.1e-10 41.7 0.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ORY17453.1 - 4.3e-05 23.1 0.2 6.9e-05 22.4 0.2 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PfkB PF00294.24 ORY17453.1 - 0.1 11.9 0.3 0.15 11.4 0.3 1.3 1 1 0 1 1 1 0 pfkB family carbohydrate kinase HTH_IclR PF09339.10 ORY17453.1 - 0.17 11.7 0.1 0.37 10.6 0.1 1.6 1 0 0 1 1 1 0 IclR helix-turn-helix domain Sugar_tr PF00083.24 ORY17454.1 - 5.5e-90 302.4 21.9 6.2e-90 302.2 21.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY17454.1 - 1.2e-24 86.9 22.5 2.1e-24 86.1 14.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 ORY17454.1 - 0.00067 18.2 2.6 0.00067 18.2 2.6 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) PTR2 PF00854.21 ORY17454.1 - 0.26 10.1 11.6 0.17 10.7 1.6 2.7 2 1 1 3 3 3 0 POT family Sugar_tr PF00083.24 ORY17455.1 - 3e-96 323.0 22.4 3.6e-96 322.8 22.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY17455.1 - 4.7e-23 81.7 20.6 4.7e-23 81.7 20.6 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily MatE PF01554.18 ORY17456.1 - 1.4e-60 203.6 33.9 2.6e-37 128.0 12.5 2.3 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 ORY17456.1 - 7.7e-07 29.3 15.1 7.7e-07 29.3 15.1 4.1 3 2 2 5 5 5 2 Polysaccharide biosynthesis C-terminal domain Pet100 PF09803.9 ORY17456.1 - 3.8 8.1 7.8 7.2 7.2 0.3 2.7 3 0 0 3 3 3 0 Pet100 COX15-CtaA PF02628.15 ORY17457.1 - 1.5e-110 369.3 9.1 1.9e-110 369.0 9.1 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein NADH-u_ox-rdase PF10785.9 ORY17457.1 - 2.1 9.1 5.5 1.9 9.2 0.0 3.3 3 1 0 3 3 3 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit BTB PF00651.31 ORY17458.1 - 0.0013 18.9 0.0 0.0025 18.0 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain HET PF06985.11 ORY17459.1 - 1.5e-22 80.5 0.3 3.3e-22 79.4 0.3 1.5 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Abhydrolase_6 PF12697.7 ORY17461.1 - 1.6e-13 51.8 0.1 8.2e-12 46.2 0.1 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ORY17461.1 - 0.015 15.0 0.1 0.04 13.6 0.1 1.7 1 1 0 1 1 1 0 alpha/beta hydrolase fold Cu_amine_oxid PF01179.20 ORY17462.1 - 3.2e-161 536.8 0.0 3.9e-161 536.5 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.16 ORY17462.1 - 1.4e-09 38.0 0.2 2.6e-09 37.2 0.2 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.16 ORY17462.1 - 8.2e-05 22.9 0.1 0.0005 20.4 0.0 2.3 2 1 0 2 2 2 1 Copper amine oxidase, N3 domain MAGUK_N_PEST PF10608.9 ORY17462.1 - 0.014 15.8 0.2 0.046 14.2 0.1 1.9 2 0 0 2 2 2 0 Polyubiquitination (PEST) N-terminal domain of MAGUK Glyco_hydro_7 PF00840.20 ORY17463.1 - 1.2e-182 607.5 17.9 1.4e-182 607.3 17.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Sugar_tr PF00083.24 ORY17464.1 - 1.8e-86 290.8 20.4 2.2e-86 290.5 20.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY17464.1 - 6.2e-16 58.3 25.2 5.9e-09 35.3 12.2 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily VIT1 PF01988.19 ORY17464.1 - 0.088 12.7 3.0 0.12 12.2 0.0 2.3 2 0 0 2 2 2 0 VIT family TauD PF02668.16 ORY17465.1 - 6.6e-49 167.1 0.2 8.2e-49 166.8 0.2 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Alpha_L_fucos PF01120.17 ORY17466.1 - 1.8e-24 86.8 0.0 4.5e-24 85.6 0.0 1.6 1 0 0 1 1 1 1 Alpha-L-fucosidase F5_F8_type_C PF00754.25 ORY17466.1 - 1.3e-10 41.4 1.1 2.6e-10 40.5 0.3 1.9 2 0 0 2 2 2 1 F5/8 type C domain adh_short_C2 PF13561.6 ORY17467.1 - 2.8e-51 174.3 1.7 5.7e-51 173.3 1.7 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY17467.1 - 6.2e-43 146.5 1.5 9.4e-43 145.9 1.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORY17467.1 - 2.7e-10 40.4 0.8 1.2e-09 38.4 0.3 1.9 2 0 0 2 2 2 1 KR domain FMO-like PF00743.19 ORY17468.1 - 2.1e-18 66.0 0.1 4.1e-17 61.8 0.1 2.3 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 ORY17468.1 - 6.7e-15 55.1 0.0 2.1e-14 53.5 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 ORY17468.1 - 4.7e-08 32.6 0.0 1.6e-05 24.2 0.1 3.3 4 0 0 4 4 4 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 ORY17468.1 - 8e-07 28.6 0.0 1.9e-05 24.1 0.0 2.8 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ORY17468.1 - 1.9e-05 24.1 0.0 0.0012 18.1 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ORY17468.1 - 0.0001 22.3 0.0 0.0029 17.6 0.0 3.0 3 0 0 3 3 3 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 ORY17468.1 - 0.03 13.4 0.0 0.048 12.7 0.0 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.17 ORY17468.1 - 0.038 13.2 0.0 0.26 10.5 0.0 2.0 2 0 0 2 2 2 0 Thi4 family DAO PF01266.24 ORY17468.1 - 0.086 12.4 0.2 0.72 9.4 0.2 2.8 1 1 0 1 1 1 0 FAD dependent oxidoreductase ADH_N PF08240.12 ORY17469.1 - 2.4e-23 82.1 0.2 4.3e-23 81.3 0.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORY17469.1 - 1.3e-19 70.5 0.2 3.6e-19 69.0 0.1 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 ORY17469.1 - 9.2e-12 44.9 0.1 1.5e-11 44.2 0.1 1.3 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus NAD_binding_7 PF13241.6 ORY17469.1 - 0.0012 19.2 0.0 0.0022 18.4 0.0 1.3 1 0 0 1 1 1 1 Putative NAD(P)-binding ADH_zinc_N_2 PF13602.6 ORY17469.1 - 0.0035 18.4 0.0 0.0068 17.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.6 ORY17469.1 - 0.024 14.6 0.1 0.024 14.6 0.1 2.7 3 0 0 3 3 3 0 Alcohol dehydrogenase GroES-associated Pyr_redox PF00070.27 ORY17469.1 - 0.073 13.6 0.0 0.18 12.4 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 ORY17469.1 - 0.11 12.6 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 ORY17469.1 - 0.15 12.3 0.0 0.28 11.4 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain DUF759 PF05537.11 ORY17470.1 - 0.096 11.5 0.6 0.13 11.1 0.6 1.1 1 0 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF759) Hamartin PF04388.12 ORY17470.1 - 5.9 5.4 5.8 7.9 5.0 5.8 1.1 1 0 0 1 1 1 0 Hamartin protein HET PF06985.11 ORY17471.1 - 1.2e-12 48.4 0.0 1.3e-12 48.3 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF4813 PF16072.5 ORY17473.1 - 0.098 12.3 16.8 0.15 11.7 16.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) DUF3275 PF11679.8 ORY17473.1 - 9.3 6.2 7.8 9.2 6.2 6.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3275) DUF2433 PF10360.9 ORY17474.1 - 3.2e-48 162.9 0.0 4.8e-48 162.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) Metallophos PF00149.28 ORY17474.1 - 0.0012 19.4 0.0 0.0021 18.6 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 ORY17474.1 - 0.014 15.6 0.0 0.047 13.9 0.0 1.8 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain HEAT PF02985.22 ORY17475.1 - 4e-17 60.9 3.3 0.00062 19.8 0.1 8.9 9 0 0 9 9 7 3 HEAT repeat HEAT_2 PF13646.6 ORY17475.1 - 7.8e-17 61.5 1.8 0.0033 17.8 0.0 7.7 6 2 2 8 8 8 4 HEAT repeats HEAT_EZ PF13513.6 ORY17475.1 - 2.4e-16 59.9 7.0 0.00016 22.1 0.1 9.2 11 0 0 11 11 9 3 HEAT-like repeat IBN_N PF03810.19 ORY17475.1 - 3.2e-12 46.2 0.7 1.1e-11 44.5 0.7 2.0 1 0 0 1 1 1 1 Importin-beta N-terminal domain Vac14_Fab1_bd PF12755.7 ORY17475.1 - 3.6e-08 33.9 0.0 0.98 10.1 0.0 5.7 6 0 0 6 6 6 3 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 ORY17475.1 - 1.4e-05 25.2 0.0 0.27 11.3 0.0 4.2 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 ORY17475.1 - 2.4e-05 24.5 0.8 0.85 9.8 0.0 5.4 5 1 1 6 6 6 2 Required for nuclear transport of RNA pol II C-terminus 1 Arm PF00514.23 ORY17475.1 - 2.4e-05 24.2 2.3 12 6.1 0.0 6.7 7 0 0 7 7 6 0 Armadillo/beta-catenin-like repeat IFRD PF05004.13 ORY17475.1 - 0.00051 19.2 5.2 1.3 8.0 0.0 5.6 4 2 0 5 5 5 1 Interferon-related developmental regulator (IFRD) UME PF08064.13 ORY17475.1 - 0.0053 16.7 0.0 2.3 8.2 0.0 4.5 4 0 0 4 4 4 1 UME (NUC010) domain RIX1 PF08167.12 ORY17475.1 - 0.011 15.4 0.0 3.8 7.2 0.0 4.4 3 2 1 4 4 4 0 rRNA processing/ribosome biogenesis MMS19_C PF12460.8 ORY17475.1 - 0.017 14.3 0.0 0.79 8.8 0.0 3.3 3 0 0 3 3 3 0 RNAPII transcription regulator C-terminal DUF4042 PF13251.6 ORY17475.1 - 0.033 13.9 1.0 8 6.1 0.0 4.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4042) Proteasom_PSMB PF10508.9 ORY17475.1 - 0.065 11.7 0.2 7.4 4.9 0.0 3.6 5 0 0 5 5 5 0 Proteasome non-ATPase 26S subunit Cohesin_HEAT PF12765.7 ORY17475.1 - 0.14 12.5 0.0 8.6 6.8 0.0 2.9 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion Phage_sheath_1N PF17481.2 ORY17475.1 - 0.16 12.4 0.1 0.39 11.2 0.1 1.6 1 0 0 1 1 1 0 Phage tail sheath protein beta-sandwich domain NPC1_N PF16414.5 ORY17476.1 - 8.4e-82 274.4 9.5 1.2e-81 273.8 9.5 1.2 1 0 0 1 1 1 1 Niemann-Pick C1 N terminus Patched PF02460.18 ORY17476.1 - 5.6e-73 246.4 4.0 1.6e-72 244.8 4.0 1.6 1 1 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 ORY17476.1 - 3e-50 170.0 5.6 3e-50 170.0 5.6 3.2 2 1 1 3 3 3 1 Sterol-sensing domain of SREBP cleavage-activation Folate_rec PF03024.14 ORY17476.1 - 1.4e-05 25.0 0.8 3.3e-05 23.8 0.8 1.5 1 0 0 1 1 1 1 Folate receptor family ACR_tran PF00873.19 ORY17476.1 - 7.6e-05 20.6 10.4 7.6e-05 20.6 10.4 1.6 2 0 0 2 2 2 1 AcrB/AcrD/AcrF family MMPL PF03176.15 ORY17476.1 - 0.00031 19.8 29.0 0.00039 19.5 10.0 2.5 2 0 0 2 2 2 2 MMPL family TraQ PF09679.10 ORY17480.1 - 0.21 11.5 0.9 0.36 10.8 0.0 1.8 2 0 0 2 2 2 0 Type-F conjugative transfer system pilin chaperone (TraQ) Peptidase_M20 PF01546.28 ORY17481.1 - 2.4e-24 86.2 0.0 9.3e-24 84.3 0.0 1.9 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 WD40 PF00400.32 ORY17481.1 - 9.8e-14 51.5 5.2 0.00075 20.3 0.0 5.9 7 0 0 7 7 7 4 WD domain, G-beta repeat M20_dimer PF07687.14 ORY17481.1 - 1.3e-06 28.2 0.0 2.8e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain WD40_like PF17005.5 ORY17481.1 - 0.0053 16.1 0.0 1.2 8.4 0.0 2.2 2 0 0 2 2 2 2 WD40-like domain ANAPC4_WD40 PF12894.7 ORY17481.1 - 0.0069 16.7 0.0 0.58 10.5 0.0 2.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain NACHT PF05729.12 ORY17482.1 - 1.2e-08 35.1 0.0 4.5e-08 33.2 0.0 2.0 2 1 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 ORY17482.1 - 0.0014 19.0 0.4 0.043 14.2 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 ORY17482.1 - 0.0074 16.6 0.2 0.31 11.3 0.0 3.1 3 1 0 3 3 3 1 AAA domain Takusan PF04822.13 ORY17482.1 - 0.0088 15.9 0.6 0.072 13.0 1.1 2.1 2 0 0 2 2 2 1 Takusan RNA_helicase PF00910.22 ORY17482.1 - 0.011 16.1 0.0 0.04 14.3 0.0 2.0 1 0 0 1 1 1 0 RNA helicase AAA_30 PF13604.6 ORY17482.1 - 0.053 13.2 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 ORY17482.1 - 0.064 13.8 0.0 0.18 12.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 ORY17482.1 - 0.091 11.9 0.0 0.79 8.9 0.0 2.4 3 0 0 3 3 3 0 NB-ARC domain KAP_NTPase PF07693.14 ORY17482.1 - 0.098 11.9 3.3 5.7 6.1 0.2 3.0 3 1 1 4 4 4 0 KAP family P-loop domain Tuberin PF03542.16 ORY17482.1 - 0.1 11.7 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Tuberin p450 PF00067.22 ORY17483.1 - 0.00022 20.1 0.0 0.0016 17.2 0.0 1.9 1 1 1 2 2 2 2 Cytochrome P450 DUF848 PF05852.11 ORY17485.1 - 0.02 15.0 0.1 0.043 13.9 0.1 1.5 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) kleA_kleC PF17383.2 ORY17485.1 - 0.072 13.4 0.1 1.6 9.1 0.1 2.6 2 0 0 2 2 2 0 Uncharacterized KorC regulated protein A Peptidase_S10 PF00450.22 ORY17486.1 - 6.7e-101 338.7 0.5 8.6e-101 338.4 0.5 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase F-box PF00646.33 ORY17488.1 - 0.00039 20.2 2.0 0.0012 18.6 2.0 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 ORY17488.1 - 0.0099 15.8 1.4 0.02 14.8 1.4 1.5 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 ORY17488.1 - 0.036 14.0 0.1 0.064 13.1 0.1 1.4 1 0 0 1 1 1 0 F-box HET PF06985.11 ORY17489.1 - 6.9e-37 127.0 0.2 1.9e-36 125.6 0.2 1.8 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Glyco_hydro_92 PF07971.12 ORY17491.1 - 2.2e-135 452.2 2.4 2.6e-135 451.9 2.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 ORY17491.1 - 4.4e-36 125.0 0.1 6.3e-36 124.5 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain EthD PF07110.11 ORY17492.1 - 2.8e-20 73.2 0.2 3.6e-20 72.9 0.2 1.1 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 ORY17492.1 - 0.00027 21.4 0.0 0.00041 20.8 0.0 1.3 1 1 0 1 1 1 1 Methylmuconolactone methyl-isomerase HET PF06985.11 ORY17493.1 - 9e-18 65.0 0.2 9.8e-18 64.9 0.2 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Hexapep_loop PF18776.1 ORY17493.1 - 0.033 13.8 0.0 0.055 13.1 0.0 1.3 1 0 0 1 1 1 0 Hexapeptide repeat including loop Peptidase_S9 PF00326.21 ORY17494.1 - 4.8e-05 22.9 0.6 0.00015 21.3 0.5 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family Esterase_phd PF10503.9 ORY17494.1 - 0.00026 20.6 0.0 0.00043 19.8 0.0 1.5 1 0 0 1 1 1 1 Esterase PHB depolymerase Esterase PF00756.20 ORY17494.1 - 0.00035 20.3 0.0 0.00049 19.8 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.16 ORY17494.1 - 0.0018 18.1 0.0 0.0043 16.9 0.0 1.5 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase AXE1 PF05448.12 ORY17494.1 - 0.0029 16.3 0.2 0.023 13.4 0.0 1.9 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) DLH PF01738.18 ORY17494.1 - 0.22 11.1 0.0 0.4 10.2 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family Glyco_hydro_59 PF02057.15 ORY17495.1 - 1.8e-13 50.4 0.1 3.7e-13 49.4 0.1 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 59 Glyco_hydr_30_2 PF14587.6 ORY17495.1 - 8.9e-11 42.0 2.9 4.4e-10 39.7 0.1 2.6 2 1 0 2 2 2 1 O-Glycosyl hydrolase family 30 Glyco_hydro_30 PF02055.16 ORY17495.1 - 1.4e-10 40.7 0.0 2e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_30C PF17189.4 ORY17495.1 - 5.5e-05 23.3 0.4 0.00014 22.0 0.4 1.8 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain Herpes_capsid PF06112.11 ORY17496.1 - 0.5 10.4 3.1 0.68 10.0 3.1 1.2 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein OCD_Mu_crystall PF02423.15 ORY17497.1 - 0.13 11.1 0.2 0.16 10.9 0.2 1.1 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family SET PF00856.28 ORY17501.1 - 0.12 12.7 0.0 0.17 12.2 0.0 1.4 1 0 0 1 1 1 0 SET domain Astacin PF01400.24 ORY17502.1 - 0.032 13.8 0.1 0.042 13.4 0.1 1.2 1 0 0 1 1 1 0 Astacin (Peptidase family M12A) OTT_1508_deam PF14441.6 ORY17504.1 - 1.3e-15 57.2 3.3 1.3e-15 57.2 3.3 2.1 2 0 0 2 2 2 1 OTT_1508-like deaminase APOBEC3 PF18771.1 ORY17504.1 - 0.012 15.7 0.0 0.039 14.1 0.0 1.8 1 0 0 1 1 1 0 APOBEC3 APOBEC2 PF18772.1 ORY17504.1 - 0.095 12.7 0.8 0.23 11.5 0.8 1.6 1 0 0 1 1 1 0 APOBEC2 Oxidored_FMN PF00724.20 ORY17505.1 - 8.9e-66 222.5 0.0 1.1e-65 222.2 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.17 ORY17505.1 - 0.0072 15.4 0.0 0.014 14.5 0.0 1.4 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) HSP70 PF00012.20 ORY17506.1 - 1.7e-260 865.4 15.7 2e-260 865.2 15.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 ORY17506.1 - 1.1e-19 70.4 1.4 1.2e-18 67.0 0.5 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 ORY17506.1 - 0.0025 18.2 5.5 2 8.9 0.0 3.6 3 1 0 3 3 3 2 Cell division protein FtsA Ppx-GppA PF02541.16 ORY17506.1 - 0.027 13.9 1.7 0.055 12.9 0.1 2.0 2 0 0 2 2 2 0 Ppx/GppA phosphatase family FGGY_C PF02782.16 ORY17506.1 - 0.093 12.4 0.0 0.68 9.6 0.0 2.3 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.18 ORY17506.1 - 0.32 10.2 5.1 0.4 9.9 0.1 3.0 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase CBP_BcsO PF17037.5 ORY17507.1 - 0.46 10.6 6.8 0.68 10.1 6.8 1.2 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsO TALPID3 PF15324.6 ORY17507.1 - 6.5 4.3 8.9 8.5 3.9 8.9 1.1 1 0 0 1 1 1 0 Hedgehog signalling target KCH PF16944.5 ORY17509.1 - 1.4e-94 316.6 14.5 1.7e-94 316.3 14.5 1.1 1 0 0 1 1 1 1 Fungal potassium channel SLY PF12485.8 ORY17509.1 - 0.021 15.6 1.0 0.041 14.6 1.0 1.4 1 0 0 1 1 1 0 Lymphocyte signaling adaptor protein Pyr_redox_2 PF07992.14 ORY17510.1 - 2.2e-15 56.7 0.0 5.2e-15 55.5 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ORY17510.1 - 2.8e-10 39.9 0.0 1.5e-09 37.4 0.0 2.0 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.19 ORY17510.1 - 1.7e-09 36.7 0.3 2.9e-08 32.6 0.3 2.1 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 ORY17510.1 - 4e-08 33.4 0.0 6.8e-07 29.4 0.1 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 ORY17510.1 - 7.5e-07 28.7 0.0 4.8e-05 22.8 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 ORY17510.1 - 4.1e-06 26.1 0.1 7.9e-05 21.9 0.1 2.6 2 1 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 ORY17510.1 - 0.00012 21.3 0.1 0.00023 20.4 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 ORY17510.1 - 0.00034 20.3 2.0 0.013 15.1 1.0 2.9 2 1 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 ORY17510.1 - 0.00063 19.1 0.1 0.03 13.6 0.4 2.3 2 0 0 2 2 2 1 FAD binding domain Amino_oxidase PF01593.24 ORY17510.1 - 0.00094 18.6 0.0 0.72 9.1 0.0 2.5 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase GIDA PF01134.22 ORY17510.1 - 0.0023 17.1 0.0 0.049 12.7 0.0 2.6 3 0 0 3 3 3 1 Glucose inhibited division protein A Pyr_redox PF00070.27 ORY17510.1 - 0.0026 18.3 0.9 0.82 10.3 0.4 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 ORY17510.1 - 0.0077 16.7 0.0 0.4 11.2 0.0 2.4 2 0 0 2 2 2 1 Putative NAD(P)-binding HI0933_like PF03486.14 ORY17510.1 - 0.094 11.4 0.2 0.29 9.8 0.2 1.8 2 0 0 2 2 2 0 HI0933-like protein ThiF PF00899.21 ORY17510.1 - 0.19 11.1 0.7 1.5 8.1 0.0 2.4 2 1 1 3 3 3 0 ThiF family FAD_oxidored PF12831.7 ORY17510.1 - 0.23 10.7 0.4 0.78 9.0 0.2 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase Rubredoxin PF00301.20 ORY17512.1 - 0.041 13.9 0.0 0.058 13.4 0.0 1.2 1 0 0 1 1 1 0 Rubredoxin MFS_1 PF07690.16 ORY17513.1 - 1.9e-43 148.7 41.6 3.4e-43 147.9 41.6 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 ORY17513.1 - 2.4e-18 65.9 10.8 3.4e-18 65.4 10.8 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 ORY17513.1 - 8.8e-15 54.5 12.0 8.8e-15 54.5 12.0 2.8 2 1 1 3 3 3 1 Sugar (and other) transporter MFS_2 PF13347.6 ORY17513.1 - 0.00021 20.0 5.2 0.00021 20.0 5.2 2.9 2 1 0 2 2 2 1 MFS/sugar transport protein DUF3433 PF11915.8 ORY17514.1 - 5.8e-36 122.8 11.7 9.1e-18 64.5 3.5 4.1 3 0 0 3 3 3 3 Protein of unknown function (DUF3433) Glyco_hydro_61 PF03443.14 ORY17515.1 - 9.1e-36 123.7 0.2 1.1e-35 123.4 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Rrn6 PF10214.9 ORY17518.1 - 0.41 9.1 10.3 0.6 8.5 10.3 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DUF1769 PF08588.10 ORY17521.1 - 1.5e-23 82.7 0.8 1.5e-23 82.7 0.8 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1769) Apt1 PF10351.9 ORY17521.1 - 0.83 8.4 4.1 1.3 7.8 4.1 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain FAD_binding_2 PF00890.24 ORY17522.1 - 7.1e-59 200.0 1.6 8.2e-59 199.7 1.6 1.0 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 ORY17522.1 - 1.3e-08 34.9 0.4 1e-07 32.0 0.1 2.5 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ORY17522.1 - 2.1e-08 34.2 0.5 5.5e-08 32.8 0.5 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ORY17522.1 - 3.3e-05 23.3 2.2 0.0001 21.6 0.8 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 ORY17522.1 - 3.3e-05 23.2 0.8 0.0013 18.0 0.0 2.3 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.7 ORY17522.1 - 0.00082 18.8 0.5 0.0024 17.3 0.5 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 ORY17522.1 - 0.00084 18.7 0.4 0.0019 17.5 0.4 1.6 1 1 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 ORY17522.1 - 0.0017 17.1 6.6 0.027 13.2 0.3 3.1 2 1 1 3 3 3 1 HI0933-like protein Amino_oxidase PF01593.24 ORY17522.1 - 0.0027 17.1 0.0 0.0053 16.1 0.0 1.5 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 ORY17522.1 - 0.0032 18.0 0.1 0.013 16.0 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 ORY17522.1 - 0.01 14.9 2.6 0.016 14.3 0.5 2.1 2 1 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_9 PF13454.6 ORY17522.1 - 0.081 12.9 0.1 0.34 10.9 0.1 1.9 1 1 0 2 2 2 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 ORY17522.1 - 0.12 11.4 0.1 0.22 10.5 0.1 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein MCRA PF06100.11 ORY17522.1 - 0.23 10.2 0.1 0.36 9.6 0.1 1.3 1 0 0 1 1 1 0 MCRA family SDA1 PF05285.12 ORY17524.1 - 0.00095 18.7 18.8 0.001 18.6 18.8 1.1 1 0 0 1 1 1 1 SDA1 DUF913 PF06025.12 ORY17524.1 - 0.0027 16.7 1.6 0.28 10.1 2.7 2.0 2 0 0 2 2 2 1 Domain of Unknown Function (DUF913) Nop14 PF04147.12 ORY17524.1 - 0.013 13.8 23.5 0.017 13.4 23.5 1.1 1 0 0 1 1 1 0 Nop14-like family RR_TM4-6 PF06459.12 ORY17524.1 - 0.016 15.1 5.2 0.017 15.0 5.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Zip PF02535.22 ORY17524.1 - 0.029 13.6 0.5 0.033 13.4 0.5 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter PTPRCAP PF15713.5 ORY17524.1 - 0.076 13.3 23.9 0.15 12.4 23.9 1.4 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated CPSF100_C PF13299.6 ORY17524.1 - 0.15 12.2 6.1 0.24 11.6 6.1 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal RNA_pol_Rpc4 PF05132.14 ORY17524.1 - 0.16 12.4 4.4 0.22 12.0 4.4 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 SAPS PF04499.15 ORY17524.1 - 0.19 10.5 5.6 0.2 10.4 5.6 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CobT PF06213.12 ORY17524.1 - 0.23 10.8 23.9 0.33 10.3 23.9 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CDC45 PF02724.14 ORY17524.1 - 0.83 7.9 25.8 1.1 7.5 25.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Connexin PF00029.19 ORY17524.1 - 1.6 8.5 4.6 2.2 8.0 4.6 1.2 1 0 0 1 1 1 0 Connexin Mpp10 PF04006.12 ORY17524.1 - 2.6 6.4 28.0 3.5 6.0 28.0 1.1 1 0 0 1 1 1 0 Mpp10 protein RNA_polI_A34 PF08208.11 ORY17524.1 - 3 7.9 16.5 4.3 7.4 16.5 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Presenilin PF01080.17 ORY17524.1 - 9.1 4.9 9.5 12 4.5 9.5 1.1 1 0 0 1 1 1 0 Presenilin DUF2828 PF11443.8 ORY17525.1 - 0.005 15.0 11.2 0.01 14.0 11.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF2828) DUF4407 PF14362.6 ORY17525.1 - 2.2 7.5 10.4 3.8 6.8 10.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) zf-GRF PF06839.12 ORY17526.1 - 0.062 13.4 1.3 0.062 13.4 1.3 2.1 2 0 0 2 2 2 0 GRF zinc finger zf-C2HC_2 PF13913.6 ORY17527.1 - 0.075 12.9 0.1 0.14 12.1 0.1 1.4 1 0 0 1 1 1 0 zinc-finger of a C2HC-type Med15 PF09606.10 ORY17527.1 - 1.4 7.5 36.4 0.0084 14.9 26.5 2.0 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.9 ORY17527.1 - 4.8 5.3 19.1 7.2 4.7 19.1 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 GREB1 PF15782.5 ORY17527.1 - 7.8 3.5 13.7 11 2.9 13.7 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer ABC_tran PF00005.27 ORY17528.1 - 9.6e-38 129.8 3.8 8.6e-18 65.2 0.0 4.0 3 1 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 ORY17528.1 - 7.4e-12 45.7 5.8 3e-08 33.8 0.1 4.1 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ORY17528.1 - 3.1e-10 39.9 2.2 0.098 12.1 0.2 4.2 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain ABC_tran_Xtn PF12848.7 ORY17528.1 - 2.3e-08 33.9 4.4 2.3e-08 33.9 4.4 2.5 3 1 0 3 3 1 1 ABC transporter AAA_29 PF13555.6 ORY17528.1 - 2.8e-07 30.2 0.4 0.00079 19.1 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 ORY17528.1 - 6.7e-05 22.9 0.4 0.023 14.6 0.0 2.7 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 ORY17528.1 - 0.0002 21.4 0.1 0.97 9.5 0.0 3.1 3 0 0 3 3 3 2 50S ribosome-binding GTPase NACHT PF05729.12 ORY17528.1 - 0.00044 20.2 3.4 0.36 10.7 0.0 3.6 4 0 0 4 4 3 1 NACHT domain AAA_16 PF13191.6 ORY17528.1 - 0.0005 20.5 3.4 0.25 11.7 0.8 2.7 2 1 0 2 2 2 2 AAA ATPase domain AAA_30 PF13604.6 ORY17528.1 - 0.00072 19.3 0.4 0.084 12.6 0.0 3.1 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 ORY17528.1 - 0.0011 19.5 1.6 0.44 11.0 0.0 3.4 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 ORY17528.1 - 0.002 17.7 1.2 0.34 10.5 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 ORY17528.1 - 0.0028 17.9 0.5 0.12 12.6 0.1 2.7 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 ORY17528.1 - 0.0057 17.2 13.5 1.4 9.4 9.0 3.3 2 1 0 2 2 2 2 AAA domain AAA_18 PF13238.6 ORY17528.1 - 0.0083 16.7 1.4 3.8 8.1 0.0 3.1 2 1 0 2 2 2 1 AAA domain T2SSE PF00437.20 ORY17528.1 - 0.0085 15.2 0.3 0.065 12.3 0.0 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_7 PF12775.7 ORY17528.1 - 0.012 15.1 0.1 0.32 10.5 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region NTPase_1 PF03266.15 ORY17528.1 - 0.021 14.7 3.0 5.5 6.9 0.0 3.3 3 0 0 3 3 3 0 NTPase DUF815 PF05673.13 ORY17528.1 - 0.025 13.8 0.3 0.085 12.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF815) TsaE PF02367.17 ORY17528.1 - 0.036 14.1 0.1 3.3 7.7 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_15 PF13175.6 ORY17528.1 - 0.051 13.3 6.4 0.14 11.8 0.0 3.2 3 1 0 3 3 3 0 AAA ATPase domain RNA_helicase PF00910.22 ORY17528.1 - 0.057 13.8 0.0 2.7 8.4 0.0 2.4 2 0 0 2 2 2 0 RNA helicase FtsK_SpoIIIE PF01580.18 ORY17528.1 - 0.071 12.5 0.5 1.4 8.2 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_24 PF13479.6 ORY17528.1 - 0.08 12.6 0.5 7.8 6.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 ORY17528.1 - 0.092 12.3 2.1 3.3 7.3 0.3 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.22 ORY17528.1 - 0.1 11.8 3.8 7.8 5.6 0.4 3.0 3 0 0 3 3 3 0 NB-ARC domain AAA_28 PF13521.6 ORY17528.1 - 0.14 12.4 4.4 0.45 10.7 0.0 3.3 3 0 0 3 3 3 0 AAA domain AAA_5 PF07728.14 ORY17528.1 - 0.17 11.8 1.1 1.6 8.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) MeaB PF03308.16 ORY17528.1 - 0.26 10.2 3.1 2.7 6.9 0.1 2.6 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_33 PF13671.6 ORY17528.1 - 9.5 6.4 14.3 5 7.3 0.5 3.7 4 0 0 4 4 4 0 AAA domain DnaJ_C PF01556.18 ORY17529.1 - 3.4e-18 66.2 0.0 4.7e-18 65.7 0.0 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain zf-C3HC4_3 PF13920.6 ORY17529.1 - 0.03 14.2 2.1 0.054 13.4 2.1 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORY17529.1 - 0.032 14.3 3.3 0.081 13.0 3.3 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4 PF00097.25 ORY17529.1 - 0.11 12.4 2.2 0.24 11.3 2.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORY17529.1 - 0.13 12.3 4.5 0.26 11.3 4.5 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.6 ORY17529.1 - 0.77 10.1 4.3 1.6 9.1 4.3 1.5 1 0 0 1 1 1 0 Ring finger domain EzrA PF06160.12 ORY17530.1 - 0.01 14.1 0.4 0.014 13.7 0.4 1.3 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA YabA PF06156.13 ORY17530.1 - 0.031 14.9 0.6 0.051 14.2 0.6 1.4 1 0 0 1 1 1 0 Initiation control protein YabA THOC7 PF05615.13 ORY17530.1 - 0.041 14.2 1.3 0.041 14.2 1.3 1.6 2 0 0 2 2 2 0 Tho complex subunit 7 DUF848 PF05852.11 ORY17530.1 - 0.052 13.7 4.7 0.098 12.8 1.5 2.0 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) SesA PF17107.5 ORY17530.1 - 0.062 13.5 2.1 0.2 11.8 0.5 2.4 2 1 1 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases DUF4201 PF13870.6 ORY17530.1 - 0.16 11.7 7.7 0.11 12.2 3.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) TCO89 PF10452.9 ORY17533.1 - 1.3e-06 27.7 1.3 0.00033 19.8 0.0 3.5 3 1 0 3 3 3 2 TORC1 subunit TCO89 Dicty_REP PF05086.12 ORY17533.1 - 5.4 4.9 8.8 7.4 4.4 8.8 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein MBOAT PF03062.19 ORY17535.1 - 0.055 12.8 0.1 0.067 12.5 0.1 1.1 1 0 0 1 1 1 0 MBOAT, membrane-bound O-acyltransferase family AJAP1_PANP_C PF15298.6 ORY17536.1 - 0.19 11.9 5.2 0.22 11.7 5.2 1.0 1 0 0 1 1 1 0 AJAP1/PANP C-terminus Paramyxo_C PF01692.18 ORY17536.1 - 1 8.7 2.1 1.6 8.1 2.1 1.4 1 1 0 1 1 1 0 Paramyxovirus non-structural protein C ORC2 PF04084.14 ORY17556.1 - 8.7e-77 258.2 0.0 9.6e-77 258.1 0.0 1.0 1 0 0 1 1 1 1 Origin recognition complex subunit 2 ORC6 PF05460.13 ORY17558.1 - 0.2 10.9 9.2 0.23 10.7 9.2 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) NOA36 PF06524.12 ORY17558.1 - 0.41 9.9 23.4 0.46 9.8 23.4 1.0 1 0 0 1 1 1 0 NOA36 protein Paf1 PF03985.13 ORY17558.1 - 1.6 7.6 30.3 1.7 7.6 30.3 1.1 1 0 0 1 1 1 0 Paf1 RMI1_N PF08585.12 ORY17558.1 - 2.7 7.7 11.8 3.3 7.4 11.8 1.1 1 0 0 1 1 1 0 RecQ mediated genome instability protein Pox_Ag35 PF03286.14 ORY17558.1 - 3.9 7.2 28.4 5.4 6.8 28.4 1.3 1 1 0 1 1 1 0 Pox virus Ag35 surface protein DUF4820 PF16091.5 ORY17558.1 - 3.9 6.8 15.0 5.1 6.4 15.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Afi1 PF07792.12 ORY17558.1 - 5.4 7.5 15.5 7.5 7.0 15.5 1.3 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking MDM1 PF15501.6 ORY17558.1 - 8.8 5.3 25.0 8.9 5.3 25.0 1.1 1 0 0 1 1 1 0 Nuclear protein MDM1 RICTOR_N PF14664.6 ORY17558.1 - 9.6 5.1 5.4 12 4.8 5.4 1.1 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, N-term Zn_clus PF00172.18 ORY17559.1 - 5.5e-09 36.0 10.7 1.5e-08 34.6 10.7 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.26 ORY17559.1 - 0.2 12.1 0.8 0.72 10.4 0.8 2.0 1 0 0 1 1 1 0 Zinc finger, C2H2 type Epimerase PF01370.21 ORY17560.1 - 6.4e-12 45.4 0.3 2.3e-11 43.7 0.3 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 ORY17560.1 - 3.8e-07 30.2 0.1 3.9e-06 26.9 0.0 2.1 2 0 0 2 2 2 1 NAD(P)H-binding 3Beta_HSD PF01073.19 ORY17560.1 - 3.7e-06 26.1 0.0 0.00035 19.7 0.0 2.0 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 ORY17560.1 - 7.7e-05 22.2 0.1 7.7e-05 22.2 0.1 1.7 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 ORY17560.1 - 0.00092 18.8 0.1 0.0032 17.1 0.1 1.9 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.25 ORY17560.1 - 0.061 12.8 0.0 0.43 10.0 0.0 2.1 2 0 0 2 2 2 0 short chain dehydrogenase MFS_2 PF13347.6 ORY17561.1 - 1.7e-11 43.3 4.1 1.7e-11 43.3 4.1 3.2 4 0 0 4 4 4 2 MFS/sugar transport protein PUCC PF03209.15 ORY17561.1 - 5.6e-05 22.3 1.5 5.6e-05 22.3 1.5 1.7 2 0 0 2 2 2 1 PUCC protein Na_H_Exchanger PF00999.21 ORY17562.1 - 1.3e-72 244.7 36.8 1.6e-72 244.4 36.8 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Glyco_hydro_6 PF01341.17 ORY17563.1 - 1.5e-102 343.5 2.3 1.9e-102 343.1 2.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 His_biosynth PF00977.21 ORY17564.1 - 3.5e-31 108.4 0.0 4.8e-31 108.0 0.0 1.1 1 0 0 1 1 1 1 Histidine biosynthesis protein Ribul_P_3_epim PF00834.19 ORY17564.1 - 0.11 11.9 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family Polysacc_deac_1 PF01522.21 ORY17565.1 - 0.036 14.0 0.0 0.064 13.1 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide deacetylase SNF2_N PF00176.23 ORY17566.1 - 1.5e-73 247.5 1.5 1.5e-73 247.5 1.5 2.0 2 0 0 2 2 2 1 SNF2 family N-terminal domain Bromodomain PF00439.25 ORY17566.1 - 7.3e-23 80.5 0.9 2e-22 79.0 0.9 1.9 1 0 0 1 1 1 1 Bromodomain Helicase_C PF00271.31 ORY17566.1 - 3.5e-22 78.8 1.3 4e-19 69.0 0.0 4.1 3 1 1 4 4 4 1 Helicase conserved C-terminal domain HSA PF07529.13 ORY17566.1 - 9.5e-17 61.1 13.1 9.5e-17 61.1 13.1 3.6 3 1 1 4 4 4 1 HSA SnAC PF14619.6 ORY17566.1 - 5.2e-14 52.6 0.3 5.2e-14 52.6 0.3 3.9 3 0 0 3 3 3 1 Snf2-ATP coupling, chromatin remodelling complex QLQ PF08880.11 ORY17566.1 - 2.1e-12 46.6 3.9 7e-12 44.9 3.9 2.0 1 0 0 1 1 1 1 QLQ ResIII PF04851.15 ORY17566.1 - 1.4e-10 41.4 0.1 1.4e-10 41.4 0.1 4.0 4 1 0 4 4 4 1 Type III restriction enzyme, res subunit DUF463 PF04317.12 ORY17567.1 - 0.15 11.0 0.1 0.2 10.5 0.1 1.1 1 0 0 1 1 1 0 YcjX-like family, DUF463 AXE1 PF05448.12 ORY17567.1 - 0.16 10.6 0.1 0.29 9.8 0.1 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) SBP PF03110.14 ORY17568.1 - 0.054 13.8 0.2 0.13 12.5 0.1 1.7 2 0 0 2 2 2 0 SBP domain APOBEC3 PF18771.1 ORY17568.1 - 0.15 12.1 0.3 0.34 11.0 0.3 1.7 1 1 0 1 1 1 0 APOBEC3 VCBS PF13517.6 ORY17569.1 - 3.1e-13 50.1 23.0 2e-05 25.1 0.1 6.2 4 2 1 5 5 5 5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Lipase_GDSL_2 PF13472.6 ORY17569.1 - 2.8e-05 24.6 0.2 0.00014 22.4 0.2 2.2 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family TcdB_toxin_midN PF12256.8 ORY17569.1 - 0.00016 21.1 0.3 0.22 10.9 0.0 3.5 3 0 0 3 3 3 1 Insecticide toxin TcdB middle/N-terminal region FG-GAP PF01839.23 ORY17569.1 - 0.002 18.2 13.7 0.44 10.7 0.1 4.5 3 0 0 3 3 3 2 FG-GAP repeat Lipase_GDSL PF00657.22 ORY17569.1 - 0.0025 17.8 0.0 0.0063 16.5 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Dockerin_1 PF00404.18 ORY17569.1 - 0.17 12.1 9.9 12 6.2 1.9 4.8 5 1 0 5 5 5 0 Dockerin type I domain PHD PF00628.29 ORY17570.1 - 0.00017 21.4 9.2 0.00017 21.4 9.2 2.0 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.6 ORY17570.1 - 0.0021 17.6 3.2 0.0021 17.6 3.2 2.0 2 0 0 2 2 2 1 PHD-finger DUF825 PF05695.12 ORY17570.1 - 0.0028 14.9 0.1 0.0039 14.4 0.1 1.1 1 0 0 1 1 1 1 Plant protein of unknown function (DUF825) zf-HC5HC2H PF13771.6 ORY17570.1 - 0.018 15.3 0.9 0.2 11.9 0.2 2.5 2 0 0 2 2 2 0 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 ORY17570.1 - 0.06 13.5 0.1 0.35 11.1 0.0 2.2 2 0 0 2 2 2 0 PHD-zinc-finger like domain zf-C2H2_jaz PF12171.8 ORY17570.1 - 2.2 8.6 5.8 0.66 10.3 2.2 2.0 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding DUF4187 PF13821.6 ORY17570.1 - 9.1 6.1 8.1 0.66 9.8 2.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4187) Ser_hydrolase PF06821.13 ORY17573.1 - 0.1 12.4 0.0 0.12 12.2 0.0 1.1 1 0 0 1 1 1 0 Serine hydrolase Myb_DNA-binding PF00249.31 ORY17574.1 - 9.9e-07 28.9 0.0 1.8e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORY17574.1 - 3.6e-05 23.9 0.0 5.6e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Inhibitor_I34 PF10466.9 ORY17574.1 - 0.037 14.6 1.0 0.043 14.4 0.1 1.6 2 0 0 2 2 2 0 Saccharopepsin inhibitor I34 PACT_coil_coil PF10495.9 ORY17574.1 - 0.41 11.3 2.3 0.51 10.9 0.6 1.9 1 1 1 2 2 2 0 Pericentrin-AKAP-450 domain of centrosomal targeting protein LRS4 PF10422.9 ORY17575.1 - 0.0022 17.6 0.5 0.004 16.8 0.5 1.5 1 0 0 1 1 1 1 Monopolin complex subunit LRS4 DUF812 PF05667.11 ORY17575.1 - 0.0099 14.8 1.0 0.013 14.4 1.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF812) CALCOCO1 PF07888.11 ORY17575.1 - 0.034 13.0 9.4 0.058 12.3 9.4 1.2 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like AAA_13 PF13166.6 ORY17575.1 - 0.16 10.6 3.3 0.27 9.8 3.3 1.2 1 0 0 1 1 1 0 AAA domain Golgin_A5 PF09787.9 ORY17575.1 - 0.43 10.0 9.0 0.77 9.2 9.0 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 Nup88 PF10168.9 ORY17575.1 - 2.8 5.6 4.5 4.3 5.0 4.5 1.1 1 0 0 1 1 1 0 Nuclear pore component DUF3584 PF12128.8 ORY17575.1 - 4.5 4.6 9.6 6.7 4.1 9.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) GrpE PF01025.19 ORY17575.1 - 8.4 6.0 7.6 18 5.0 7.6 1.5 1 0 0 1 1 1 0 GrpE Methyltransf_31 PF13847.6 ORY17576.1 - 3.3e-21 75.7 0.0 4.6e-21 75.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORY17576.1 - 3.4e-17 62.6 0.0 5.3e-17 61.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 ORY17576.1 - 9.6e-17 61.5 0.0 1.7e-16 60.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain GFA PF04828.14 ORY17576.1 - 1.1e-15 57.8 0.9 1.9e-15 57.0 0.9 1.4 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Methyltransf_11 PF08241.12 ORY17576.1 - 3.9e-14 53.1 0.0 6.7e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY17576.1 - 2.7e-12 47.3 0.0 4.6e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY17576.1 - 7.3e-10 38.9 0.0 1.1e-09 38.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 ORY17576.1 - 1.1e-08 35.1 0.0 2.1e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.19 ORY17576.1 - 4e-05 23.8 0.0 8.4e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_32 PF13679.6 ORY17576.1 - 0.00059 19.8 0.0 0.00098 19.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ORY17576.1 - 0.007 15.9 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_24 PF13578.6 ORY17576.1 - 0.025 15.6 0.0 0.05 14.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DOT1 PF08123.13 ORY17576.1 - 0.23 10.9 0.0 0.39 10.2 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 CorA PF01544.18 ORY17577.1 - 6.2e-10 38.9 4.4 1.9e-09 37.3 4.4 1.8 1 1 1 2 2 2 1 CorA-like Mg2+ transporter protein TSNAXIP1_N PF15739.5 ORY17577.1 - 0.072 13.5 0.1 0.21 12.0 0.1 1.8 1 0 0 1 1 1 0 Translin-associated factor X-interacting N-terminus SNF2_N PF00176.23 ORY17578.1 - 6.3e-54 183.0 0.0 1e-52 179.0 0.0 2.3 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ORY17578.1 - 5.3e-17 62.2 0.0 1.4e-15 57.6 0.0 3.0 4 0 0 4 4 4 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.25 ORY17578.1 - 4e-05 23.4 10.0 4e-05 23.4 10.0 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) AAA_34 PF13872.6 ORY17578.1 - 8.9e-05 21.5 0.0 0.0002 20.4 0.0 1.6 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 DEAD PF00270.29 ORY17578.1 - 0.00062 19.6 0.0 0.0014 18.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DRAT PF07357.11 ORY17578.1 - 0.0061 15.8 0.0 0.013 14.7 0.0 1.5 1 0 0 1 1 1 1 Dinitrogenase reductase ADP-ribosyltransferase (DRAT) ERCC3_RAD25_C PF16203.5 ORY17578.1 - 0.025 13.8 0.0 0.068 12.4 0.0 1.7 2 0 0 2 2 2 0 ERCC3/RAD25/XPB C-terminal helicase Zn_Tnp_IS91 PF14319.6 ORY17578.1 - 0.99 9.5 13.6 5.4 7.1 1.4 2.6 2 0 0 2 2 2 0 Transposase zinc-binding domain zf-RING_5 PF14634.6 ORY17578.1 - 1.3 9.0 23.1 0.015 15.3 10.6 2.4 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4_3 PF13920.6 ORY17578.1 - 4.5 7.2 20.0 0.025 14.4 9.3 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) HPP PF04982.13 ORY17579.1 - 2e-34 118.4 4.2 2e-34 118.4 4.2 1.9 1 1 1 2 2 2 1 HPP family FAM176 PF14851.6 ORY17579.1 - 0.0078 15.9 0.0 0.012 15.3 0.0 1.2 1 0 0 1 1 1 1 FAM176 family ABC_tran PF00005.27 ORY17580.1 - 6.2e-48 162.8 0.1 8.7e-24 84.6 0.0 2.8 3 0 0 3 3 2 2 ABC transporter ABC_tran_Xtn PF12848.7 ORY17580.1 - 1e-21 76.7 5.4 1e-21 76.7 5.4 2.2 3 0 0 3 3 1 1 ABC transporter AAA_21 PF13304.6 ORY17580.1 - 1.3e-19 71.1 0.4 0.0006 19.7 0.2 4.3 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ORY17580.1 - 2.5e-11 43.4 0.5 0.0032 17.0 0.1 4.5 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 ORY17580.1 - 8.1e-10 39.5 2.0 0.015 15.8 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.6 ORY17580.1 - 6e-09 35.5 0.1 0.0036 17.0 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.6 ORY17580.1 - 5.3e-08 33.0 0.1 0.015 15.1 0.0 3.2 3 0 0 3 3 3 2 AAA ATPase domain RsgA_GTPase PF03193.16 ORY17580.1 - 6.4e-07 29.4 0.1 0.0015 18.5 0.0 2.7 3 0 0 3 3 2 2 RsgA GTPase AAA_16 PF13191.6 ORY17580.1 - 1.2e-06 29.0 0.0 0.0079 16.6 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_18 PF13238.6 ORY17580.1 - 1.4e-05 25.7 0.1 0.083 13.4 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_22 PF13401.6 ORY17580.1 - 2.4e-05 24.6 0.0 0.074 13.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 ORY17580.1 - 7.9e-05 22.7 0.0 0.097 12.8 0.0 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_27 PF13514.6 ORY17580.1 - 0.00024 20.8 0.9 0.18 11.4 0.0 2.7 3 0 0 3 3 2 2 AAA domain NACHT PF05729.12 ORY17580.1 - 0.00024 21.0 0.1 0.71 9.8 0.0 2.5 2 0 0 2 2 2 2 NACHT domain AAA_28 PF13521.6 ORY17580.1 - 0.0003 21.1 0.0 0.1 12.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 ORY17580.1 - 0.00097 19.1 0.1 2.1 8.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA PF00004.29 ORY17580.1 - 0.00098 19.6 0.0 1.2 9.6 0.0 2.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 ORY17580.1 - 0.0012 19.2 1.1 2.5 8.6 0.0 3.2 3 0 0 3 3 3 2 RNA helicase Roc PF08477.13 ORY17580.1 - 0.0013 18.9 0.1 1.9 8.7 0.1 3.1 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase NB-ARC PF00931.22 ORY17580.1 - 0.0014 17.8 0.0 3 7.0 0.0 3.2 2 1 0 2 2 2 2 NB-ARC domain AAA_24 PF13479.6 ORY17580.1 - 0.0059 16.3 1.5 2.4 7.8 0.1 3.2 3 0 0 3 3 3 1 AAA domain AAA_14 PF13173.6 ORY17580.1 - 0.014 15.5 0.1 5.2 7.1 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_7 PF12775.7 ORY17580.1 - 0.017 14.7 0.0 0.94 9.0 0.0 2.6 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_33 PF13671.6 ORY17580.1 - 0.018 15.2 1.4 2.6 8.2 0.0 3.1 4 0 0 4 4 2 0 AAA domain Rad17 PF03215.15 ORY17580.1 - 0.029 14.3 0.0 8.7 6.2 0.0 2.6 2 0 0 2 2 2 0 Rad17 P-loop domain Ras PF00071.22 ORY17580.1 - 0.032 13.8 0.2 7.6 6.1 0.0 2.7 3 0 0 3 3 3 0 Ras family Phage_tail_2 PF06199.11 ORY17580.1 - 0.033 14.3 0.0 0.094 12.8 0.0 1.8 1 0 0 1 1 1 0 Phage tail tube protein PduV-EutP PF10662.9 ORY17580.1 - 0.037 13.8 0.4 3.6 7.3 0.0 3.1 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation DUF2813 PF11398.8 ORY17580.1 - 0.039 13.2 0.4 8.7 5.5 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2813) AAA_25 PF13481.6 ORY17580.1 - 0.041 13.5 0.0 1.7 8.2 0.0 3.1 3 0 0 3 3 3 0 AAA domain ATPase_2 PF01637.18 ORY17580.1 - 0.07 13.0 0.3 17 5.2 0.0 2.7 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea AAA_30 PF13604.6 ORY17580.1 - 0.073 12.8 0.7 4.5 6.9 0.0 3.0 3 1 0 3 3 2 0 AAA domain ABC_ATPase PF09818.9 ORY17580.1 - 0.084 11.6 0.1 21 3.7 0.0 3.2 3 1 0 3 3 3 0 Predicted ATPase of the ABC class Dynamin_N PF00350.23 ORY17580.1 - 0.23 11.5 2.7 49 3.9 0.0 3.6 3 1 1 4 4 3 0 Dynamin family CLTH PF10607.9 ORY17581.1 - 1.6e-28 99.5 0.0 3e-28 98.6 0.0 1.5 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 ORY17581.1 - 0.0029 17.5 0.0 0.0065 16.4 0.0 1.6 1 0 0 1 1 1 1 LisH PLU-1 PF08429.11 ORY17581.1 - 0.026 13.7 0.5 0.039 13.1 0.5 1.2 1 0 0 1 1 1 0 PLU-1-like protein NRBF2 PF08961.10 ORY17581.1 - 0.052 13.1 0.3 0.091 12.4 0.3 1.3 1 0 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator U-box PF04564.15 ORY17581.1 - 0.08 13.1 0.0 0.19 11.9 0.0 1.6 1 0 0 1 1 1 0 U-box domain APG6_N PF17675.1 ORY17581.1 - 0.38 11.3 2.8 0.68 10.5 2.8 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF2431 PF10354.9 ORY17582.1 - 3e-54 183.8 0.0 4.1e-54 183.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) Pol_alpha_B_N PF08418.10 ORY17582.1 - 0.11 12.4 3.2 0.2 11.6 3.2 1.4 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal CoA_binding PF02629.19 ORY17583.1 - 2.4e-25 89.1 1.1 2.4e-25 89.1 1.1 2.2 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 ORY17583.1 - 5.4e-25 88.0 0.2 1.1e-24 86.9 0.2 1.5 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 ORY17583.1 - 2.1e-09 37.3 0.0 4.3e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 ORY17583.1 - 4.5e-06 27.1 0.0 1.2e-05 25.7 0.0 1.8 1 0 0 1 1 1 1 CoA binding domain Radical_SAM_C PF16199.5 ORY17584.1 - 1.5e-32 111.5 0.1 3.6e-32 110.2 0.1 1.7 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 ORY17584.1 - 2.5e-17 63.8 0.1 1.1e-16 61.6 0.0 2.0 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 ORY17584.1 - 6.8e-10 39.2 0.0 1.4e-09 38.2 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ORY17584.1 - 4e-06 26.8 0.1 2.2e-05 24.4 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ORY17584.1 - 0.015 15.7 0.1 0.036 14.5 0.1 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF202 PF02656.15 ORY17585.1 - 0.064 13.7 1.0 0.12 12.8 0.9 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF202) DUF2892 PF11127.8 ORY17585.1 - 0.13 12.3 4.0 0.38 10.8 4.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2892) Tetraspanin PF00335.20 ORY17585.1 - 2.3 7.9 6.4 2.9 7.5 6.4 1.1 1 0 0 1 1 1 0 Tetraspanin family CVNH PF08881.10 ORY17586.1 - 1e-13 51.8 3.7 1.4e-13 51.4 3.7 1.2 1 0 0 1 1 1 1 CVNH domain DUF3328 PF11807.8 ORY17589.1 - 7.2e-29 101.1 0.1 9.4e-29 100.8 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF4303 PF14136.6 ORY17590.1 - 0.12 12.1 0.5 6.7 6.4 0.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4303) Adap_comp_sub PF00928.21 ORY17592.1 - 1.3e-85 286.9 0.0 1.7e-85 286.6 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 ORY17592.1 - 1.5e-05 24.9 0.2 2.8e-05 24.1 0.2 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 ORY17592.1 - 0.0066 15.9 0.2 0.011 15.2 0.2 1.4 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain RIBIOP_C PF04950.12 ORY17592.1 - 0.045 13.2 0.0 0.073 12.5 0.0 1.2 1 0 0 1 1 1 0 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal Synaptobrevin PF00957.21 ORY17593.1 - 0.0019 18.0 0.4 0.017 14.9 0.3 2.0 1 1 1 2 2 2 2 Synaptobrevin BLOC1_2 PF10046.9 ORY17593.1 - 0.0047 17.2 0.0 0.006 16.9 0.0 1.2 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 DegS PF05384.11 ORY17593.1 - 0.046 13.2 0.0 0.053 13.0 0.0 1.1 1 0 0 1 1 1 0 Sensor protein DegS Laminin_I PF06008.14 ORY17593.1 - 0.046 13.4 0.1 0.055 13.2 0.1 1.1 1 0 0 1 1 1 0 Laminin Domain I Seryl_tRNA_N PF02403.22 ORY17593.1 - 0.063 13.5 0.1 0.077 13.2 0.1 1.1 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF948 PF06103.11 ORY17593.1 - 0.083 13.2 0.1 0.42 10.9 0.0 1.8 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) AAA_22 PF13401.6 ORY17594.1 - 0.04 14.2 0.0 0.07 13.4 0.0 1.4 1 1 0 1 1 1 0 AAA domain Ank_4 PF13637.6 ORY17595.1 - 0.0092 16.5 0.0 0.021 15.4 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 ORY17595.1 - 0.017 15.5 0.0 0.056 13.9 0.0 1.8 2 0 0 2 2 2 0 Ankyrin repeat S1-P1_nuclease PF02265.16 ORY17596.1 - 6.9e-75 252.1 0.1 8e-75 251.9 0.1 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease DUF2195 PF09961.9 ORY17596.1 - 0.11 12.4 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2195) DER1 PF04511.15 ORY17597.1 - 2.8e-48 164.4 5.7 3.1e-48 164.2 5.7 1.0 1 0 0 1 1 1 1 Der1-like family Histone PF00125.24 ORY17598.1 - 1.4e-39 135.5 0.0 1.8e-39 135.1 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 ORY17598.1 - 0.00019 21.5 0.0 0.00029 20.9 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 ORY17598.1 - 0.00054 20.3 0.0 0.00081 19.7 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 ORY17598.1 - 0.026 14.6 0.0 0.039 14.0 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit CBFD_NFYB_HMF PF00808.23 ORY17598.1 - 0.067 13.5 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.13 ORY17598.1 - 0.18 11.9 0.0 0.28 11.2 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated DUF5549 PF17703.1 ORY17598.1 - 0.72 9.5 5.6 1.1 8.9 5.6 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5549) Forkhead PF00250.18 ORY17599.1 - 3e-35 120.4 0.3 5.1e-35 119.6 0.3 1.4 1 0 0 1 1 1 1 Forkhead domain Peptidase_S10 PF00450.22 ORY17601.1 - 1.6e-85 288.0 0.6 3.1e-85 287.1 0.6 1.4 1 1 0 1 1 1 1 Serine carboxypeptidase HET PF06985.11 ORY17602.1 - 2.9e-33 115.3 0.4 5.7e-33 114.3 0.4 1.5 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Aminotran_5 PF00266.19 ORY17605.1 - 9.4e-30 103.8 0.0 1.7e-29 103.0 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V MORN PF02493.20 ORY17606.1 - 1.7e-13 49.6 19.9 0.0061 16.4 0.9 4.8 4 0 0 4 4 4 4 MORN repeat USP7_ICP0_bdg PF12436.8 ORY17606.1 - 2.5e-13 49.9 0.0 5.6e-12 45.5 0.0 2.2 2 0 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 zf-C3HC4_3 PF13920.6 ORY17606.1 - 2.8e-11 43.1 6.6 5e-11 42.3 6.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 ORY17606.1 - 0.00013 21.8 6.4 0.00025 20.8 6.4 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 UCH PF00443.29 ORY17606.1 - 0.00034 20.2 0.0 0.00054 19.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-RING_2 PF13639.6 ORY17606.1 - 0.0095 16.3 7.8 0.0095 16.3 7.8 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 ORY17606.1 - 0.19 11.6 12.0 0.26 11.1 6.7 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORY17606.1 - 0.23 11.3 11.1 0.84 9.6 6.3 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORY17606.1 - 0.57 10.2 12.5 0.13 12.2 6.6 2.3 2 0 0 2 2 2 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 ORY17606.1 - 5 7.2 5.7 32 4.7 1.2 3.0 2 1 1 3 3 3 0 RING-type zinc-finger DS PF01916.17 ORY17607.1 - 3.5e-132 440.0 0.0 4e-132 439.8 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase Myb_DNA-binding PF00249.31 ORY17608.1 - 6.5e-11 42.3 0.0 3.3e-07 30.4 0.0 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORY17608.1 - 2.2e-05 24.6 0.2 0.14 12.5 0.0 2.9 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 ORY17608.1 - 0.00038 20.3 0.0 0.00038 20.3 0.0 2.2 2 0 0 2 2 2 1 Myb DNA-binding like Tub PF01167.18 ORY17608.1 - 0.16 11.7 3.6 0.32 10.7 3.6 1.5 1 0 0 1 1 1 0 Tub family Glyco_transf_15 PF01793.16 ORY17609.1 - 1.1e-120 402.9 6.9 8.5e-120 399.9 7.1 1.9 2 0 0 2 2 2 1 Glycolipid 2-alpha-mannosyltransferase Luteo_Vpg PF01659.16 ORY17611.1 - 0.0049 17.2 0.4 0.0078 16.5 0.4 1.3 1 0 0 1 1 1 1 Luteovirus putative VPg genome linked protein SGL PF08450.12 ORY17613.1 - 7.3e-20 71.6 0.0 1.3e-19 70.7 0.0 1.4 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region FAR1 PF03101.15 ORY17613.1 - 4e-06 27.4 0.2 7.8e-06 26.5 0.2 1.4 1 0 0 1 1 1 1 FAR1 DNA-binding domain Arylesterase PF01731.20 ORY17613.1 - 0.00066 19.8 0.0 0.0018 18.4 0.0 1.7 1 0 0 1 1 1 1 Arylesterase AFT PF08731.11 ORY17613.1 - 0.052 13.9 0.3 0.093 13.1 0.3 1.4 1 0 0 1 1 1 0 Transcription factor AFT Chlorovi_GP_rpt PF06598.11 ORY17613.1 - 0.056 13.5 0.0 0.18 11.9 0.0 1.9 1 0 0 1 1 1 0 Chlorovirus glycoprotein repeat AMP-binding PF00501.28 ORY17614.1 - 1.3e-69 234.8 0.0 1.7e-69 234.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORY17614.1 - 8.5e-07 29.9 0.5 2.2e-06 28.6 0.0 2.0 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain Metal_CEHH PF14455.6 ORY17614.1 - 0.14 11.8 0.0 0.3 10.7 0.0 1.5 1 0 0 1 1 1 0 Predicted metal binding domain VSP PF03302.13 ORY17615.1 - 0.024 13.5 0.4 0.034 13.0 0.4 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein Syndecan PF01034.20 ORY17615.1 - 0.11 12.4 1.0 0.22 11.4 1.0 1.4 1 0 0 1 1 1 0 Syndecan domain Ribonucleas_3_3 PF14622.6 ORY17616.1 - 8.8e-17 61.5 0.0 1.6e-16 60.6 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 ORY17616.1 - 9.3e-15 55.1 0.5 2.7e-14 53.7 0.0 2.0 2 0 0 2 2 2 1 Ribonuclease III domain dsrm PF00035.26 ORY17616.1 - 0.0013 19.4 0.1 0.0057 17.3 0.0 2.2 2 0 0 2 2 2 1 Double-stranded RNA binding motif Med19 PF10278.9 ORY17616.1 - 1 9.3 12.6 2.4 8.1 12.6 1.6 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 CDC45 PF02724.14 ORY17616.1 - 1.4 7.2 6.0 2.1 6.5 6.0 1.3 1 0 0 1 1 1 0 CDC45-like protein MRP-S33 PF08293.11 ORY17617.1 - 4.2e-30 103.8 0.0 5.3e-30 103.5 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 MFS_1 PF07690.16 ORY17618.1 - 1e-36 126.6 28.3 1e-36 126.6 28.3 2.5 1 1 2 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY17618.1 - 2.8e-09 36.3 2.5 2.8e-09 36.3 2.5 2.3 3 0 0 3 3 3 1 Sugar (and other) transporter 4HBT PF03061.22 ORY17619.1 - 3.9e-08 33.5 0.2 7.6e-08 32.6 0.2 1.5 1 1 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 ORY17619.1 - 0.0025 18.1 0.0 0.0034 17.7 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily Pyr_redox_3 PF13738.6 ORY17620.1 - 9.9e-09 34.9 0.0 1.8e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ORY17620.1 - 2.9e-08 33.3 0.1 6.1e-08 32.2 0.0 1.6 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.19 ORY17620.1 - 1.8e-06 26.7 0.0 2.3e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 ORY17620.1 - 0.00036 19.9 0.1 0.00073 18.9 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DUF4147 PF13660.6 ORY17620.1 - 0.018 14.6 0.0 0.023 14.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4147) Pyr_redox PF00070.27 ORY17620.1 - 0.28 11.8 0.8 0.56 10.8 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HET PF06985.11 ORY17621.1 - 1.2e-36 126.2 0.4 2.2e-36 125.4 0.4 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) GARS_A PF01071.19 ORY17622.1 - 1.9e-83 279.1 0.0 3e-83 278.4 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.15 ORY17622.1 - 1.7e-32 112.0 0.0 5.2e-32 110.5 0.0 1.8 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.16 ORY17622.1 - 3.2e-27 94.6 0.7 8.8e-27 93.2 0.7 1.8 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain ATP-grasp_3 PF02655.14 ORY17622.1 - 0.0001 22.4 0.0 0.00028 21.0 0.0 1.8 2 0 0 2 2 2 1 ATP-grasp domain CPSase_L_D2 PF02786.17 ORY17622.1 - 0.00013 21.5 0.4 0.00041 19.9 0.0 2.0 3 0 0 3 3 3 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp PF02222.22 ORY17622.1 - 0.00018 21.1 0.0 0.00035 20.2 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.6 ORY17622.1 - 0.0028 17.3 0.0 0.0062 16.1 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 ORY17622.1 - 0.023 14.3 0.0 0.045 13.3 0.0 1.4 1 0 0 1 1 1 0 RimK-like ATP-grasp domain ALF PF03752.13 ORY17622.1 - 0.042 13.8 0.0 0.16 11.9 0.0 2.0 1 0 0 1 1 1 0 Short repeats of unknown function Dala_Dala_lig_C PF07478.13 ORY17622.1 - 0.043 13.3 0.0 0.16 11.5 0.0 1.8 2 0 0 2 2 2 0 D-ala D-ala ligase C-terminus ATP-grasp_2 PF08442.10 ORY17622.1 - 0.085 12.4 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain Exo_endo_phos PF03372.23 ORY17623.1 - 5.5e-06 26.1 0.0 1.2e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RhoGAP PF00620.27 ORY17623.1 - 0.019 14.8 0.0 0.039 13.8 0.0 1.4 1 0 0 1 1 1 0 RhoGAP domain DCP1 PF06058.13 ORY17624.1 - 4.4e-27 94.3 0.0 5.7e-27 94.0 0.0 1.2 1 0 0 1 1 1 1 Dcp1-like decapping family PelD_GGDEF PF16963.5 ORY17624.1 - 0.042 13.7 0.0 1.7 8.4 0.0 2.2 2 0 0 2 2 2 0 PelD GGDEF domain LIDHydrolase PF10230.9 ORY17625.1 - 1.3e-68 231.4 0.0 1.6e-68 231.2 0.0 1.1 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_6 PF12697.7 ORY17625.1 - 5.5e-05 23.9 0.3 7.3e-05 23.5 0.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF900 PF05990.12 ORY17625.1 - 0.00012 21.7 0.0 0.00027 20.5 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Hydrolase_4 PF12146.8 ORY17625.1 - 0.06 12.6 0.0 0.087 12.1 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 LCAT PF02450.15 ORY17625.1 - 0.16 11.1 0.0 0.5 9.5 0.0 1.7 1 1 0 1 1 1 0 Lecithin:cholesterol acyltransferase Protocadherin PF08374.11 ORY17627.1 - 0.07 13.1 0.2 0.089 12.8 0.2 1.3 1 0 0 1 1 1 0 Protocadherin DUF2244 PF10003.9 ORY17630.1 - 0.017 14.8 0.3 0.021 14.5 0.3 1.2 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) BRI3BP PF14965.6 ORY17630.1 - 0.98 8.9 4.0 1.2 8.6 0.9 2.0 1 1 1 2 2 2 0 Negative regulator of p53/TP53 TPR_2 PF07719.17 ORY17631.1 - 2.4e-23 80.3 29.4 0.0023 17.9 0.1 12.6 15 0 0 15 15 12 6 Tetratricopeptide repeat TPR_1 PF00515.28 ORY17631.1 - 4.3e-20 70.6 27.9 0.00017 21.3 0.2 10.1 13 0 0 13 13 11 6 Tetratricopeptide repeat TPR_19 PF14559.6 ORY17631.1 - 1.4e-16 60.7 25.2 0.00012 22.6 0.3 9.2 6 3 3 10 10 10 6 Tetratricopeptide repeat TPR_12 PF13424.6 ORY17631.1 - 3.8e-13 49.5 25.2 0.027 14.7 0.5 10.2 9 2 1 10 10 10 5 Tetratricopeptide repeat TPR_11 PF13414.6 ORY17631.1 - 5.9e-12 45.1 9.5 0.025 14.2 0.2 7.0 6 1 1 7 7 7 3 TPR repeat TPR_7 PF13176.6 ORY17631.1 - 8.8e-12 44.2 21.3 0.001 19.0 0.0 9.2 11 0 0 11 11 10 3 Tetratricopeptide repeat TPR_14 PF13428.6 ORY17631.1 - 5.1e-11 42.4 27.2 2.3 9.3 0.1 12.8 13 3 3 16 16 13 3 Tetratricopeptide repeat TPR_16 PF13432.6 ORY17631.1 - 6.6e-11 42.7 19.8 0.12 13.1 0.1 9.8 10 1 0 10 10 10 3 Tetratricopeptide repeat TPR_8 PF13181.6 ORY17631.1 - 1.4e-10 40.5 21.8 0.043 14.0 0.1 9.7 11 0 0 11 11 9 4 Tetratricopeptide repeat TPR_10 PF13374.6 ORY17631.1 - 1.2e-07 31.4 16.1 0.02 14.8 0.1 7.4 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_17 PF13431.6 ORY17631.1 - 2e-07 30.9 15.1 0.21 12.0 0.2 9.8 13 0 0 13 13 11 2 Tetratricopeptide repeat TPR_6 PF13174.6 ORY17631.1 - 3.3e-06 27.4 26.1 0.32 11.7 0.0 10.3 11 0 0 11 11 9 2 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY17631.1 - 1e-05 25.7 7.4 0.029 14.6 2.2 3.9 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_3 PF07720.12 ORY17631.1 - 0.002 18.1 16.0 2.9 8.0 0.0 6.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TOM20_plant PF06552.12 ORY17631.1 - 0.022 14.5 0.5 0.14 11.8 0.1 2.5 2 0 0 2 2 2 0 Plant specific mitochondrial import receptor subunit TOM20 Fis1_TPR_C PF14853.6 ORY17631.1 - 0.024 14.7 1.8 4.1 7.5 0.2 3.6 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat DUF1279 PF06916.13 ORY17631.1 - 0.13 12.9 0.1 1.8 9.1 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1279) Sec8_exocyst PF04048.14 ORY17632.1 - 1.8e-46 157.6 2.3 1.8e-46 157.6 2.3 2.3 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain Vps54_N PF10475.9 ORY17632.1 - 4.4e-10 39.3 4.9 8.2e-10 38.4 4.9 1.3 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex Zw10 PF06248.13 ORY17632.1 - 0.00034 19.3 5.4 0.00041 19.1 4.3 1.5 2 0 0 2 2 2 1 Centromere/kinetochore Zw10 COG2 PF06148.11 ORY17632.1 - 0.018 15.1 0.5 0.058 13.5 0.5 1.9 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Vps51 PF08700.11 ORY17632.1 - 0.061 13.4 1.7 0.34 11.0 0.2 2.6 2 0 0 2 2 2 0 Vps51/Vps67 Com_YlbF PF06133.11 ORY17632.1 - 0.099 13.3 2.1 0.27 11.9 2.1 1.7 1 0 0 1 1 1 0 Control of competence regulator ComK, YlbF/YmcA FliJ PF02050.16 ORY17632.1 - 0.1 12.8 4.7 0.29 11.4 4.7 1.7 1 0 0 1 1 1 0 Flagellar FliJ protein Sec5 PF15469.6 ORY17632.1 - 0.26 11.1 2.7 0.53 10.1 2.7 1.5 1 0 0 1 1 1 0 Exocyst complex component Sec5 WXG100 PF06013.12 ORY17632.1 - 0.4 11.0 1.9 27 5.1 0.3 3.5 2 1 1 3 3 3 0 Proteins of 100 residues with WXG DUF3829 PF12889.7 ORY17632.1 - 0.89 9.0 3.2 0.31 10.5 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3829) Exonuc_VII_L PF02601.15 ORY17632.1 - 2.7 7.5 7.2 2.3 7.7 5.7 1.5 1 1 0 1 1 1 0 Exonuclease VII, large subunit PIG-P PF08510.12 ORY17633.1 - 2.8e-52 175.7 1.2 4.4e-52 175.1 1.2 1.3 1 0 0 1 1 1 1 PIG-P DPM2 PF07297.12 ORY17633.1 - 0.029 14.7 7.5 0.049 13.9 7.5 1.3 1 0 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) His_Phos_2 PF00328.22 ORY17634.1 - 5.9e-10 39.0 0.0 1.2e-07 31.4 0.0 2.1 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) MFS_1 PF07690.16 ORY17635.1 - 2e-28 99.3 32.5 3.4e-28 98.6 32.5 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily PMP1_2 PF08114.11 ORY17635.1 - 0.11 12.2 0.1 0.34 10.7 0.1 1.8 1 0 0 1 1 1 0 ATPase proteolipid family Cyclin_C_2 PF16899.5 ORY17636.1 - 4.8e-24 84.7 5.5 1.1e-23 83.5 0.2 3.3 4 0 0 4 4 4 1 Cyclin C-terminal domain Cyclin_N PF00134.23 ORY17636.1 - 0.00034 20.4 0.0 0.00064 19.5 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain DUF4638 PF15472.6 ORY17637.1 - 1.8 8.3 6.2 0.35 10.5 2.6 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4638) MAS20 PF02064.15 ORY17637.1 - 2.7 8.1 7.7 6.3 6.9 7.7 1.6 1 0 0 1 1 1 0 MAS20 protein import receptor Clr2 PF10383.9 ORY17637.1 - 7.2 7.4 8.5 32 5.3 6.2 2.4 2 0 0 2 2 2 0 Transcription-silencing protein Clr2 AAA PF00004.29 ORY17638.1 - 5.1e-41 140.2 0.2 1.5e-40 138.7 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 ORY17638.1 - 2.6e-11 43.1 0.5 5.1e-11 42.2 0.5 1.5 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 ORY17638.1 - 1.3e-09 37.9 0.1 2.4e-09 37.0 0.1 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_22 PF13401.6 ORY17638.1 - 1.9e-06 28.2 0.2 0.02 15.1 0.1 2.6 1 1 1 2 2 2 2 AAA domain AAA_2 PF07724.14 ORY17638.1 - 8.1e-06 26.1 0.0 1.7e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 ORY17638.1 - 1.4e-05 24.4 0.0 2.3e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 ORY17638.1 - 0.00011 22.3 0.1 0.00033 20.7 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 ORY17638.1 - 0.00016 22.1 0.4 0.0018 18.7 0.3 2.3 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 ORY17638.1 - 0.0003 20.6 0.0 0.00062 19.5 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 ORY17638.1 - 0.0015 18.8 0.5 0.0074 16.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 ORY17638.1 - 0.0058 17.2 0.0 0.012 16.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 ORY17638.1 - 0.01 16.0 0.1 0.026 14.7 0.0 1.8 2 0 0 2 2 1 0 AAA domain ATPase PF06745.13 ORY17638.1 - 0.014 14.7 0.1 0.51 9.6 0.1 2.2 1 1 0 2 2 2 0 KaiC IstB_IS21 PF01695.17 ORY17638.1 - 0.016 15.0 0.0 0.04 13.7 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_3 PF07726.11 ORY17638.1 - 0.019 14.8 0.0 0.04 13.8 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 ORY17638.1 - 0.023 14.6 0.2 0.55 10.1 0.2 2.5 1 1 0 1 1 1 0 NACHT domain TIP49 PF06068.13 ORY17638.1 - 0.024 13.8 1.3 0.04 13.1 0.1 2.0 2 1 0 2 2 2 0 TIP49 P-loop domain AAA_14 PF13173.6 ORY17638.1 - 0.027 14.5 0.0 0.056 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 ORY17638.1 - 0.052 13.9 0.0 0.1 13.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase PhoH PF02562.16 ORY17638.1 - 0.057 12.9 0.5 0.51 9.7 0.1 2.1 2 0 0 2 2 2 0 PhoH-like protein Mg_chelatase PF01078.21 ORY17638.1 - 0.059 12.7 0.1 0.12 11.7 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 ORY17638.1 - 0.067 12.8 1.4 0.6 9.6 0.4 2.6 1 1 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 ORY17638.1 - 0.072 12.4 0.0 0.18 11.0 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin ABC_tran PF00005.27 ORY17638.1 - 0.17 12.4 0.4 0.88 10.1 0.4 2.3 1 1 0 1 1 1 0 ABC transporter DUF2075 PF09848.9 ORY17638.1 - 0.17 11.1 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Prot_ATP_OB_N PF17758.1 ORY17638.1 - 0.23 11.2 0.6 1 9.0 0.0 2.3 2 0 0 2 2 2 0 Proteasomal ATPase OB N-terminal domain AAA_24 PF13479.6 ORY17638.1 - 0.31 10.7 2.2 0.31 10.7 0.3 2.1 2 1 0 2 2 2 0 AAA domain UQ_con PF00179.26 ORY17639.1 - 2.8e-42 143.7 0.0 3.8e-42 143.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.10 ORY17639.1 - 3.1e-06 26.9 0.0 6e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain RWD PF05773.22 ORY17639.1 - 0.05 13.9 0.0 0.079 13.3 0.0 1.4 1 0 0 1 1 1 0 RWD domain Acyltransferase PF01553.21 ORY17641.1 - 1e-26 93.1 0.0 1.8e-26 92.3 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 ORY17641.1 - 2.5e-13 49.9 0.0 4.6e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase C-terminus NAD_kinase PF01513.21 ORY17642.1 - 5.7e-47 160.3 0.0 2e-46 158.5 0.0 1.6 1 1 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 ORY17642.1 - 0.06 13.0 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain BRE1 PF08647.11 ORY17643.1 - 2.2e-26 91.8 12.7 2.2e-26 91.8 12.7 7.1 6 1 2 8 8 8 1 BRE1 E3 ubiquitin ligase zf-C3HC4_3 PF13920.6 ORY17643.1 - 1.8e-09 37.3 7.0 2.9e-09 36.6 7.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 ORY17643.1 - 5.1e-09 35.8 9.0 9.4e-09 35.0 9.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORY17643.1 - 2.6e-08 33.7 4.7 5.2e-08 32.8 4.7 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 ORY17643.1 - 2.6e-07 30.4 9.3 4.9e-07 29.5 9.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORY17643.1 - 1.5e-06 28.4 7.1 2.8e-06 27.6 7.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 ORY17643.1 - 1.7e-06 27.9 10.2 3.1e-06 27.0 10.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 ORY17643.1 - 1.9e-06 27.6 6.4 3.6e-06 26.7 6.4 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 ATG16 PF08614.11 ORY17643.1 - 0.0033 17.7 14.4 0.0033 17.7 14.4 6.0 2 2 1 5 5 4 2 Autophagy protein 16 (ATG16) zf-C3HC4_4 PF15227.6 ORY17643.1 - 0.0061 16.7 6.6 0.013 15.6 6.6 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 ORY17643.1 - 0.011 16.0 4.4 0.04 14.2 4.4 2.0 1 0 0 1 1 1 0 RING-H2 zinc finger domain JIP_LZII PF16471.5 ORY17643.1 - 0.012 15.7 0.4 0.012 15.7 0.4 8.1 7 1 1 8 8 8 0 JNK-interacting protein leucine zipper II zf-RING_6 PF14835.6 ORY17643.1 - 0.024 14.5 2.9 0.051 13.5 2.9 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-C2H2 PF00096.26 ORY17643.1 - 0.045 14.2 0.1 0.045 14.2 0.1 3.2 4 0 0 4 4 2 0 Zinc finger, C2H2 type DUF1272 PF06906.11 ORY17643.1 - 0.049 13.7 4.7 0.12 12.5 4.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-H2C2_2 PF13465.6 ORY17643.1 - 0.06 13.8 0.3 4.8 7.8 0.1 2.7 2 0 0 2 2 2 0 Zinc-finger double domain zf-RING_4 PF14570.6 ORY17643.1 - 0.23 11.3 5.6 0.59 10.0 5.7 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C2HC_2 PF13913.6 ORY17643.1 - 0.24 11.3 2.5 4.6 7.3 0.3 2.6 2 0 0 2 2 2 0 zinc-finger of a C2HC-type FYVE PF01363.21 ORY17643.1 - 0.24 11.5 10.4 0.44 10.7 6.1 2.6 1 1 1 2 2 2 0 FYVE zinc finger zf-ribbon_3 PF13248.6 ORY17643.1 - 0.27 10.7 4.6 0.047 13.1 0.9 1.8 2 0 0 2 2 1 0 zinc-ribbon domain Cript PF10235.9 ORY17643.1 - 0.29 11.7 7.4 0.26 11.9 4.1 2.8 2 0 0 2 2 1 0 Microtubule-associated protein CRIPT DZR PF12773.7 ORY17643.1 - 0.4 10.7 6.6 0.85 9.7 6.6 1.5 1 0 0 1 1 1 0 Double zinc ribbon zf-RING_10 PF16685.5 ORY17643.1 - 0.65 10.2 6.5 1.9 8.7 6.5 1.8 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-C2HE PF16278.5 ORY17643.1 - 0.7 10.4 5.5 0.54 10.8 0.5 3.5 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_4 PF13894.6 ORY17643.1 - 0.86 10.6 6.0 1 10.4 0.0 3.1 2 1 0 2 2 2 0 C2H2-type zinc finger Myb_DNA-bind_7 PF15963.5 ORY17644.1 - 3.4e-22 78.1 0.1 3.4e-22 78.1 0.1 2.1 2 0 0 2 2 2 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 ORY17644.1 - 0.0043 17.2 0.0 0.014 15.6 0.0 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain Rit1_C PF17184.4 ORY17645.1 - 4.3e-104 347.8 0.0 5.8e-104 347.3 0.0 1.2 1 0 0 1 1 1 1 Rit1 N-terminal domain Init_tRNA_PT PF04179.12 ORY17645.1 - 2.8e-31 108.1 0.0 4.8e-31 107.3 0.0 1.4 1 0 0 1 1 1 1 Rit1 DUSP-like domain MFS_1 PF07690.16 ORY17646.1 - 5.4e-34 117.7 30.9 5.4e-34 117.7 30.9 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Gti1_Pac2 PF09729.9 ORY17650.1 - 9.8e-56 188.7 0.1 9.8e-56 188.7 0.1 2.1 2 0 0 2 2 2 1 Gti1/Pac2 family RsgI_N PF12791.7 ORY17651.1 - 0.074 13.0 0.0 0.76 9.7 0.0 2.2 2 0 0 2 2 2 0 Anti-sigma factor N-terminus Ank_2 PF12796.7 ORY17652.1 - 7.3e-37 125.8 0.9 5.4e-11 42.9 0.0 4.4 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY17652.1 - 1.5e-35 121.1 1.3 7.8e-07 29.5 0.1 7.3 2 2 6 8 8 8 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 ORY17652.1 - 8.9e-29 99.2 1.8 3e-07 30.6 0.0 5.6 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY17652.1 - 2.6e-25 85.7 0.9 0.0019 18.6 0.0 7.0 7 0 0 7 7 7 6 Ankyrin repeat Ank PF00023.30 ORY17652.1 - 9.5e-25 85.9 5.2 0.00014 22.2 0.0 7.3 7 0 0 7 7 7 6 Ankyrin repeat RL PF17797.1 ORY17652.1 - 0.049 13.6 0.0 1.6 8.7 0.0 2.9 3 0 0 3 3 3 0 RL domain CH PF00307.31 ORY17653.1 - 8.2e-48 161.1 0.1 4e-23 81.7 0.0 3.0 3 0 0 3 3 3 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.10 ORY17653.1 - 3.7e-29 100.6 1.4 5e-26 90.6 0.1 2.8 2 0 0 2 2 2 2 Ca2+ insensitive EF hand CAMSAP_CH PF11971.8 ORY17653.1 - 8.5e-11 41.5 0.1 1.3e-06 28.2 0.1 2.9 2 0 0 2 2 2 2 CAMSAP CH domain EF-hand_6 PF13405.6 ORY17653.1 - 0.00064 19.5 0.6 0.015 15.2 0.0 3.2 3 0 0 3 3 3 1 EF-hand domain NADH-UOR_E PF16514.5 ORY17653.1 - 0.0051 17.1 0.2 0.22 11.9 0.0 3.2 2 1 0 2 2 2 1 putative NADH-ubiquinone oxidoreductase chain E EF-hand_1 PF00036.32 ORY17653.1 - 0.012 15.2 0.1 0.29 10.8 0.0 2.7 2 0 0 2 2 2 0 EF hand Spectrin PF00435.21 ORY17653.1 - 0.021 15.3 4.2 2.3 8.7 0.9 3.0 2 0 0 2 2 2 0 Spectrin repeat DUF2884 PF11101.8 ORY17653.1 - 0.025 14.1 7.1 0.033 13.7 0.2 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2884) EF-hand_8 PF13833.6 ORY17653.1 - 0.036 13.9 0.4 0.27 11.1 0.1 2.5 2 0 0 2 2 2 0 EF-hand domain pair FliG_N PF14842.6 ORY17653.1 - 0.072 13.6 2.2 1.2 9.7 0.2 3.1 2 1 1 3 3 3 0 FliG N-terminal domain zf-RRPl_C4 PF17026.5 ORY17653.1 - 0.077 13.1 0.2 0.36 11.0 0.0 2.1 2 0 0 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type PIN_8 PF18476.1 ORY17653.1 - 0.16 11.8 3.2 1.4 8.8 0.3 2.5 2 0 0 2 2 2 0 PIN like domain Sipho_Gp157 PF05565.11 ORY17653.1 - 0.29 11.1 6.4 1.7 8.7 0.2 2.7 3 0 0 3 3 2 0 Siphovirus Gp157 EF-hand_7 PF13499.6 ORY17653.1 - 0.54 10.8 7.4 0.07 13.6 1.0 2.9 3 0 0 3 3 3 0 EF-hand domain pair GLTSCR1 PF15249.6 ORY17653.1 - 0.6 10.6 2.8 0.64 10.5 0.8 2.1 2 0 0 2 2 2 0 Conserved region of unknown function on GLTSCR protein Tropomyosin PF00261.20 ORY17653.1 - 1.3 8.4 5.8 12 5.2 1.2 2.6 2 0 0 2 2 2 0 Tropomyosin DUF4508 PF14969.6 ORY17653.1 - 2.2 8.6 7.3 2.4 8.5 0.8 3.2 4 0 0 4 4 2 0 Domain of unknown function (DUF4508) T3SSipB PF16535.5 ORY17653.1 - 3.1 8.3 7.2 12 6.3 0.3 2.7 2 1 1 3 3 3 0 Type III cell invasion protein SipB Baculo_PEP_C PF04513.12 ORY17653.1 - 4.7 7.2 8.2 0.6 10.1 1.3 2.9 3 1 1 4 4 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Na_H_Exchanger PF00999.21 ORY17654.1 - 8.2e-28 97.3 43.1 7e-22 77.7 29.7 3.1 3 0 0 3 3 3 3 Sodium/hydrogen exchanger family Pkinase PF00069.25 ORY17655.1 - 6.7e-68 228.9 1.1 6.7e-68 228.9 1.1 2.3 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY17655.1 - 7.9e-54 182.6 1.2 9.3e-54 182.4 0.1 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase PBD PF00786.28 ORY17655.1 - 1.2e-21 76.9 0.0 3.2e-21 75.4 0.0 1.8 1 0 0 1 1 1 1 P21-Rho-binding domain PH PF00169.29 ORY17655.1 - 1.2e-07 32.2 0.0 2.6e-07 31.1 0.0 1.7 1 0 0 1 1 1 1 PH domain Pkinase_fungal PF17667.1 ORY17655.1 - 3.3e-06 26.1 0.0 3.3e-06 26.1 0.0 2.3 3 0 0 3 3 3 1 Fungal protein kinase Kinase-like PF14531.6 ORY17655.1 - 7.9e-06 25.4 0.0 1.3e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like PH_11 PF15413.6 ORY17655.1 - 0.00021 21.6 0.0 0.00094 19.6 0.0 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain Haspin_kinase PF12330.8 ORY17655.1 - 0.0063 15.5 0.0 0.013 14.5 0.0 1.5 1 0 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 ORY17655.1 - 0.011 14.8 0.0 0.019 14.0 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.23 ORY17655.1 - 0.26 11.2 7.9 0.13 12.2 0.2 3.0 2 1 1 3 3 3 0 Phosphotransferase enzyme family THOC2_N PF16134.5 ORY17656.1 - 5.8e-201 669.4 0.0 8.8e-201 668.8 0.0 1.3 1 0 0 1 1 1 1 THO complex subunit 2 N-terminus Tho2 PF11262.8 ORY17656.1 - 3.2e-82 276.1 0.9 5e-82 275.5 0.9 1.3 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.8 ORY17656.1 - 3e-23 81.7 0.0 6.9e-23 80.5 0.0 1.7 1 0 0 1 1 1 1 Transcription- and export-related complex subunit PAC3 PF10178.9 ORY17656.1 - 0.0049 17.0 0.0 0.012 15.7 0.0 1.6 1 0 0 1 1 1 1 Proteasome assembly chaperone 3 Aminotran_1_2 PF00155.21 ORY17657.1 - 1.3e-82 277.9 0.0 1.6e-82 277.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 ORY17657.1 - 6.6e-05 21.6 0.0 0.0001 20.9 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 ORY17657.1 - 7.7e-05 21.8 0.0 0.00016 20.7 0.0 1.5 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 ORY17657.1 - 0.024 13.9 0.2 0.047 13.0 0.2 1.4 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family DUF3405 PF11885.8 ORY17657.1 - 0.16 10.5 0.3 0.3 9.6 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3405) SNF2_N PF00176.23 ORY17658.1 - 1e-41 142.9 0.0 1.7e-41 142.1 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ORY17658.1 - 1.2e-20 73.9 0.0 3.3e-20 72.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 ORY17658.1 - 7.7e-05 22.0 0.0 0.00017 20.9 0.0 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase SWI2_SNF2 PF18766.1 ORY17658.1 - 0.002 17.8 0.0 0.42 10.2 0.0 2.5 2 0 0 2 2 2 2 SWI2/SNF2 ATPase SAGA-Tad1 PF12767.7 ORY17658.1 - 0.84 9.3 3.7 0.65 9.7 0.9 2.1 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit GSH_synth_ATP PF03917.17 ORY17659.1 - 1e-139 465.5 0.0 1.2e-139 465.3 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 ORY17659.1 - 5.3e-34 116.7 0.0 9e-34 116.0 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic glutathione synthase DUF4203 PF13886.6 ORY17662.1 - 4.3e-50 170.2 29.8 5.7e-50 169.8 29.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) Erf4 PF10256.9 ORY17663.1 - 3.4e-40 136.8 0.0 4.6e-40 136.3 0.0 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family TNT PF14021.6 ORY17664.1 - 1.7e-30 105.4 0.1 3e-30 104.6 0.1 1.4 1 0 0 1 1 1 1 Tuberculosis necrotizing toxin adh_short PF00106.25 ORY17665.1 - 1.2e-30 106.4 0.0 1.8e-30 105.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY17665.1 - 1.5e-20 73.8 0.0 2e-20 73.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY17665.1 - 1.3e-08 35.0 0.0 2e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ORY17665.1 - 1.2e-05 24.9 0.1 2.3e-05 24.0 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 ORY17665.1 - 0.0017 17.6 0.0 0.002 17.3 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 ORY17665.1 - 0.0096 15.1 0.0 0.019 14.0 0.0 1.5 1 0 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.13 ORY17665.1 - 0.01 15.4 0.0 0.024 14.2 0.0 1.6 2 0 0 2 2 2 0 NmrA-like family DapB_N PF01113.20 ORY17665.1 - 0.011 15.8 0.0 0.02 15.0 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NAD_binding_4 PF07993.12 ORY17665.1 - 0.015 14.5 0.0 6 6.0 0.0 2.8 2 1 1 3 3 3 0 Male sterility protein 3Beta_HSD PF01073.19 ORY17665.1 - 0.029 13.4 0.0 0.04 12.9 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF1776 PF08643.10 ORY17665.1 - 0.22 10.9 0.0 0.34 10.2 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) MMM1 PF10296.9 ORY17666.1 - 4.7e-139 463.1 0.0 5.6e-139 462.8 0.0 1.0 1 0 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 HET PF06985.11 ORY17667.1 - 4.9e-24 85.4 0.0 7.9e-24 84.7 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.7 ORY17668.1 - 3.1e-22 78.9 0.0 1.9e-10 41.2 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ORY17668.1 - 1.6e-20 72.8 0.1 7e-07 29.4 0.0 3.3 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY17668.1 - 1.4e-16 58.8 0.0 0.0069 16.8 0.0 4.9 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.6 ORY17668.1 - 9.5e-15 54.8 0.0 3.7e-07 30.6 0.0 2.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 ORY17668.1 - 4e-13 49.2 0.0 0.062 13.8 0.0 4.2 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.6 ORY17669.1 - 1e-23 83.4 2.4 1.5e-09 38.2 0.1 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 ORY17669.1 - 2.1e-19 69.9 1.4 2.6e-09 37.6 0.3 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ORY17669.1 - 4.1e-19 68.4 6.6 3.3e-08 33.6 0.1 3.5 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY17669.1 - 4.5e-19 66.5 1.6 0.0008 19.7 0.0 4.0 4 0 0 4 4 4 4 Ankyrin repeat Ank PF00023.30 ORY17669.1 - 1.1e-14 54.0 7.9 0.0026 18.1 0.0 4.1 4 0 0 4 4 4 4 Ankyrin repeat B12D PF06522.11 ORY17669.1 - 0.069 13.0 0.0 12 5.7 0.0 2.9 2 1 1 3 3 3 0 NADH-ubiquinone reductase complex 1 MLRQ subunit WHIM1 PF15612.6 ORY17670.1 - 0.0048 16.4 0.0 0.01 15.4 0.0 1.6 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 FYDLN_acid PF09538.10 ORY17670.1 - 0.88 10.3 7.7 2.5 8.8 7.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) BAR PF03114.18 ORY17671.1 - 2.7e-50 171.3 8.0 3.7e-50 170.8 8.0 1.1 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.9 ORY17671.1 - 1.1e-05 24.7 3.1 1.5e-05 24.3 3.1 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking PMEI PF04043.15 ORY17671.1 - 0.041 14.2 3.3 1.2 9.5 3.3 2.3 1 1 0 1 1 1 0 Plant invertase/pectin methylesterase inhibitor DUF913 PF06025.12 ORY17671.1 - 0.23 10.4 1.0 0.35 9.8 1.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Arfaptin PF06456.13 ORY17671.1 - 0.23 11.0 9.2 0.15 11.6 6.5 2.0 2 1 0 2 2 2 0 Arfaptin-like domain GBP_C PF02841.14 ORY17671.1 - 0.58 9.5 14.0 0.015 14.7 6.4 1.8 2 0 0 2 2 2 0 Guanylate-binding protein, C-terminal domain OmpH PF03938.14 ORY17671.1 - 2.3 8.6 14.1 1.7 9.0 8.7 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Fungal_trans PF04082.18 ORY17672.1 - 1.7e-10 40.4 0.2 3e-10 39.6 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY17672.1 - 5.7e-09 36.0 7.8 1e-08 35.1 7.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cep3 PF16846.5 ORY17672.1 - 0.012 14.1 0.0 0.018 13.5 0.0 1.1 1 0 0 1 1 1 0 Centromere DNA-binding protein complex CBF3 subunit B Sulfolobus_pRN PF05584.11 ORY17672.1 - 0.029 14.4 0.0 0.17 12.0 0.0 2.2 2 0 0 2 2 2 0 Sulfolobus plasmid regulatory protein Sec1 PF00995.23 ORY17673.1 - 1.7e-131 440.3 0.1 2e-131 440.1 0.1 1.0 1 0 0 1 1 1 1 Sec1 family EPL1 PF10513.9 ORY17673.1 - 0.1 13.0 0.0 0.26 11.7 0.0 1.6 1 0 0 1 1 1 0 Enhancer of polycomb-like Epimerase PF01370.21 ORY17674.1 - 1e-08 35.0 0.7 0.00012 21.6 0.4 2.4 3 0 0 3 3 3 2 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 ORY17674.1 - 3.3e-08 34.0 0.1 1.9e-07 31.6 0.1 2.0 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 ORY17674.1 - 6.2e-07 29.5 1.3 8.2e-07 29.1 0.6 1.7 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 ORY17674.1 - 7.8e-05 22.3 0.6 0.00013 21.6 0.1 1.6 2 0 0 2 2 2 1 NmrA-like family NAD_binding_4 PF07993.12 ORY17674.1 - 0.0097 15.1 0.0 0.015 14.4 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein GFO_IDH_MocA PF01408.22 ORY17674.1 - 0.023 15.5 0.1 0.053 14.3 0.1 1.7 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold DXP_reductoisom PF02670.16 ORY17674.1 - 0.08 13.7 0.0 0.17 12.6 0.0 1.6 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase LGFP PF08310.11 ORY17675.1 - 1.3e-47 160.1 5.0 1.1e-14 54.7 0.1 5.7 5 0 0 5 5 5 5 LGFP repeat Laminin_G_2 PF02210.24 ORY17675.1 - 0.023 15.3 0.0 0.047 14.3 0.0 1.5 1 0 0 1 1 1 0 Laminin G domain Laminin_G_3 PF13385.6 ORY17675.1 - 0.046 13.9 0.0 0.094 12.9 0.0 1.5 1 0 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily RIX1 PF08167.12 ORY17679.1 - 2.3e-55 187.2 8.4 2.3e-55 187.2 8.4 2.1 2 0 0 2 2 2 1 rRNA processing/ribosome biogenesis TPR_14 PF13428.6 ORY17680.1 - 2.3e-09 37.3 8.4 0.18 12.7 0.0 7.8 7 1 1 8 8 8 2 Tetratricopeptide repeat TPR_1 PF00515.28 ORY17680.1 - 5.1e-07 29.2 0.1 7.4 6.6 0.0 5.6 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 ORY17680.1 - 7.8e-07 28.7 3.2 2.3 8.6 0.1 6.3 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 ORY17680.1 - 3.6e-05 24.2 3.1 0.15 12.6 0.0 4.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 ORY17680.1 - 0.00055 19.9 4.2 0.58 10.5 0.0 5.9 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_17 PF13431.6 ORY17680.1 - 0.00076 19.7 0.6 1.1 9.7 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 ORY17680.1 - 0.0056 16.9 4.9 13 6.1 0.0 5.9 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_7 PF13176.6 ORY17680.1 - 0.016 15.2 0.5 40 4.6 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.6 ORY17680.1 - 0.063 13.0 0.2 2.2 8.0 0.0 2.8 2 0 0 2 2 2 0 TPR repeat TPR_9 PF13371.6 ORY17680.1 - 0.081 13.1 0.1 46 4.3 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat GlgS PF08971.11 ORY17681.1 - 0.24 11.4 0.3 0.69 10.0 0.3 1.7 1 0 0 1 1 1 0 Glycogen synthesis protein Zn_clus PF00172.18 ORY17681.1 - 0.27 11.4 7.7 0.52 10.5 7.7 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain TB2_DP1_HVA22 PF03134.19 ORY17683.1 - 1.9e-27 95.0 8.3 3.5e-27 94.1 8.3 1.4 1 0 0 1 1 1 1 TB2/DP1, HVA22 family RFX_DNA_binding PF02257.15 ORY17684.1 - 2.9e-28 98.3 0.0 7.1e-28 97.1 0.0 1.7 1 0 0 1 1 1 1 RFX DNA-binding domain zf-HYPF PF07503.12 ORY17685.1 - 0.2 11.5 1.1 0.45 10.3 1.1 1.5 1 0 0 1 1 1 0 HypF finger MBOAT_2 PF13813.6 ORY17686.1 - 4.1e-18 65.4 1.4 1.5e-17 63.6 1.4 2.0 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family MMR_HSR1_Xtn PF16897.5 ORY17687.1 - 6.3e-34 116.2 1.9 1.1e-33 115.4 0.8 1.9 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 ORY17687.1 - 5.1e-22 77.7 0.5 1.3e-21 76.4 0.1 1.9 2 0 0 2 2 2 1 TGS domain MMR_HSR1 PF01926.23 ORY17687.1 - 6.8e-21 74.5 0.0 1.7e-20 73.2 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 ORY17687.1 - 1e-12 47.9 0.0 1.7e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 ORY17687.1 - 6.8e-05 23.0 0.2 0.079 13.0 0.0 2.4 1 1 1 2 2 2 2 Dynamin family Roc PF08477.13 ORY17687.1 - 0.059 13.6 0.1 3 8.1 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase MeaB PF03308.16 ORY17687.1 - 0.086 11.8 0.1 0.18 10.8 0.1 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB MCM PF00493.23 ORY17687.1 - 0.096 11.8 0.1 0.32 10.1 0.0 1.7 2 0 0 2 2 2 0 MCM P-loop domain DUF4387 PF14330.6 ORY17687.1 - 0.12 13.0 0.1 0.25 12.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4387) PINIT PF14324.6 ORY17688.1 - 4.1e-37 127.7 0.1 1.1e-36 126.4 0.1 1.7 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.20 ORY17688.1 - 6.5e-21 73.8 4.0 1.1e-20 73.1 4.0 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 ORY17688.1 - 1.3e-07 31.3 1.6 2.9e-07 30.2 1.6 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit SAP PF02037.27 ORY17688.1 - 0.0063 16.2 0.1 0.014 15.1 0.1 1.6 1 0 0 1 1 1 1 SAP domain DUF2423 PF10338.9 ORY17689.1 - 2.8e-21 75.5 1.0 2.8e-21 75.5 1.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2423) Dynamin_N PF00350.23 ORY17690.1 - 9e-05 22.6 0.1 0.0018 18.3 0.0 2.7 2 1 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 ORY17690.1 - 0.0075 16.3 0.0 0.032 14.3 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase Nucleopor_Nup85 PF07575.13 ORY17690.1 - 0.03 12.9 1.8 0.043 12.4 0.1 2.1 2 0 0 2 2 2 0 Nup85 Nucleoporin PRT_C PF08372.10 ORY17690.1 - 0.038 13.7 0.0 0.73 9.6 0.0 2.8 3 0 0 3 3 3 0 Plant phosphoribosyltransferase C-terminal AAA_22 PF13401.6 ORY17690.1 - 0.097 12.9 0.0 0.55 10.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain Glycos_transf_1 PF00534.20 ORY17691.1 - 8.6e-22 77.5 0.0 1.4e-21 76.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 ORY17691.1 - 7.2e-15 55.6 0.0 1.7e-14 54.4 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 ORY17691.1 - 3.9e-05 23.9 0.0 9.3e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_20 PF00982.21 ORY17691.1 - 0.004 15.9 0.0 0.022 13.4 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase family 20 LIP PF03583.14 ORY17691.1 - 0.0098 15.2 0.0 0.019 14.3 0.0 1.4 1 0 0 1 1 1 1 Secretory lipase Glyco_trans_4_4 PF13579.6 ORY17691.1 - 0.039 14.4 0.0 0.2 12.1 0.0 2.0 2 0 0 2 2 2 0 Glycosyl transferase 4-like domain WD40 PF00400.32 ORY17692.1 - 1.4e-57 190.3 11.3 5.9e-09 36.4 0.4 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.10 ORY17692.1 - 1.1e-18 67.2 4.5 2.1e-18 66.4 4.5 1.5 1 0 0 1 1 1 1 Tup N-terminal ANAPC4_WD40 PF12894.7 ORY17692.1 - 1.4e-15 57.4 0.0 0.00028 21.1 0.0 5.4 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 ORY17692.1 - 3.5e-08 33.1 0.0 0.055 12.8 0.0 5.3 4 1 2 6 6 6 2 WD40-like domain Ge1_WD40 PF16529.5 ORY17692.1 - 0.00026 20.1 0.0 0.22 10.4 0.0 3.7 1 1 2 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 ORY17692.1 - 0.00095 17.9 0.3 0.074 11.7 0.0 3.4 1 1 2 4 4 4 1 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 ORY17692.1 - 0.0016 17.1 0.3 0.011 14.3 0.1 2.1 1 1 1 2 2 2 1 Cytochrome D1 heme domain Nucleoporin_N PF08801.11 ORY17692.1 - 0.0083 14.9 0.0 0.11 11.2 0.0 2.5 2 1 0 2 2 2 1 Nup133 N terminal like Nbas_N PF15492.6 ORY17692.1 - 0.05 12.9 0.1 21 4.3 0.0 3.1 1 1 3 4 4 4 0 Neuroblastoma-amplified sequence, N terminal Glu_cyclase_2 PF05096.12 ORY17692.1 - 0.089 12.2 0.1 0.29 10.5 0.1 1.8 2 0 0 2 2 2 0 Glutamine cyclotransferase Frtz PF11768.8 ORY17692.1 - 0.21 9.9 0.0 29 2.8 0.0 3.0 3 1 0 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz THP2 PF09432.10 ORY17692.1 - 0.22 11.6 0.1 0.38 10.8 0.1 1.3 1 0 0 1 1 1 0 Tho complex subunit THP2 zf-C2H2 PF00096.26 ORY17696.1 - 5.8e-18 64.3 23.4 4.1e-05 23.8 0.9 4.5 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY17696.1 - 4.4e-16 58.5 23.2 2.4e-08 34.0 0.4 4.7 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORY17696.1 - 2e-08 34.3 20.8 0.03 15.2 0.1 4.6 4 0 0 4 4 4 3 C2H2-type zinc finger zf-met PF12874.7 ORY17696.1 - 0.0043 17.4 8.9 0.47 10.9 0.0 4.0 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zf-C2H2_aberr PF17017.5 ORY17696.1 - 0.019 15.1 6.1 0.23 11.6 0.3 3.0 2 1 1 3 3 3 0 Aberrant zinc-finger zf-C2H2_8 PF15909.5 ORY17696.1 - 0.03 14.6 16.8 0.15 12.4 1.0 4.2 2 1 2 4 4 4 0 C2H2-type zinc ribbon C1_4 PF07975.12 ORY17696.1 - 0.04 14.2 1.3 2.5 8.4 0.4 2.6 2 0 0 2 2 2 0 TFIIH C1-like domain zf-C2H2_6 PF13912.6 ORY17696.1 - 0.1 12.6 0.1 0.1 12.6 0.1 4.5 4 0 0 4 4 4 0 C2H2-type zinc finger FOXP-CC PF16159.5 ORY17696.1 - 0.18 12.4 4.9 34 5.2 0.0 3.4 2 1 1 3 3 3 0 FOXP coiled-coil domain zf-DNA_Pol PF08996.10 ORY17696.1 - 0.42 10.4 6.6 4.3 7.1 0.7 2.3 1 1 1 2 2 2 0 DNA Polymerase alpha zinc finger zf-LYAR PF08790.11 ORY17696.1 - 0.96 9.4 11.7 7.1 6.6 0.5 4.2 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger FA_hydroxylase PF04116.13 ORY17698.1 - 3.4e-24 85.7 14.6 3.4e-24 85.7 14.6 2.2 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily TMEM237 PF15383.6 ORY17698.1 - 0.048 12.8 0.1 0.073 12.2 0.1 1.2 1 0 0 1 1 1 0 Transmembrane protein 237 Pex14_N PF04695.13 ORY17698.1 - 0.12 13.0 1.6 0.2 12.3 1.6 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Ribosomal_L29 PF00831.23 ORY17699.1 - 0.11 12.5 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Ribosomal L29 protein DUF4720 PF15846.5 ORY17700.1 - 0.025 14.4 0.0 0.06 13.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4720) CaiF_GrlA PF07180.11 ORY17700.1 - 0.13 12.2 0.1 0.17 11.9 0.1 1.1 1 0 0 1 1 1 0 CaiF/GrlA transcriptional regulator CDC27 PF09507.10 ORY17701.1 - 0.13 11.6 1.3 0.16 11.4 1.3 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF1180 PF06679.12 ORY17701.1 - 0.38 11.2 4.6 0.55 10.6 4.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Hamartin PF04388.12 ORY17701.1 - 0.44 9.2 4.6 0.42 9.2 4.6 1.1 1 0 0 1 1 1 0 Hamartin protein T5orf172 PF10544.9 ORY17703.1 - 7.1e-28 97.2 2.5 3.7e-27 94.9 2.5 2.2 1 1 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 ORY17703.1 - 3.5e-24 85.3 0.2 8.7e-24 84.0 0.2 1.7 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 Myb_DNA-binding PF00249.31 ORY17749.1 - 0.047 13.9 0.0 0.1 12.8 0.0 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain Fumble PF03630.14 ORY17750.1 - 9e-144 478.7 0.0 1.1e-143 478.3 0.0 1.1 1 0 0 1 1 1 1 Fumble SlyX PF04102.12 ORY17751.1 - 0.099 13.3 0.3 0.73 10.5 0.1 2.2 2 0 0 2 2 2 0 SlyX DUF1192 PF06698.11 ORY17751.1 - 0.21 11.7 0.6 0.83 9.8 0.2 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1192) SKA2 PF16740.5 ORY17752.1 - 0.36 10.6 4.0 0.27 11.0 0.8 2.0 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 FliJ PF02050.16 ORY17752.1 - 0.71 10.1 8.1 0.096 12.9 1.5 2.2 2 0 0 2 2 2 0 Flagellar FliJ protein HIP1_clath_bdg PF16515.5 ORY17752.1 - 1.3 9.7 7.5 0.37 11.4 1.6 2.1 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Crystall PF00030.19 ORY17753.1 - 0.0024 18.0 0.0 0.0038 17.4 0.0 1.3 1 0 0 1 1 1 1 Beta/Gamma crystallin DIM PF08194.12 ORY17753.1 - 0.0066 16.6 0.0 0.0066 16.6 0.0 1.9 2 0 0 2 2 2 1 DIM protein DHHA2 PF02833.14 ORY17754.1 - 0.0044 17.2 0.0 0.0069 16.6 0.0 1.2 1 0 0 1 1 1 1 DHHA2 domain TRM PF02005.16 ORY17755.1 - 2.2e-114 382.5 0.0 6.1e-99 331.7 0.0 2.1 2 0 0 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase Argos PF11581.8 ORY17755.1 - 0.048 13.7 0.1 0.11 12.5 0.1 1.6 1 0 0 1 1 1 0 Antagonist of EGFR signalling, Argos Ferritin_2 PF13668.6 ORY17756.1 - 1.2e-16 61.1 0.0 1.9e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 Ferritin-like domain Pex14_N PF04695.13 ORY17757.1 - 5.9e-41 140.7 1.1 5.9e-41 140.7 1.1 3.0 2 1 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Golgin_A5 PF09787.9 ORY17757.1 - 0.074 12.5 0.5 0.14 11.6 0.5 1.4 1 0 0 1 1 1 0 Golgin subfamily A member 5 Baculo_PEP_C PF04513.12 ORY17757.1 - 0.13 12.3 0.5 9.9 6.2 0.2 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus FUSC PF04632.12 ORY17757.1 - 0.55 8.7 1.9 0.85 8.1 1.9 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF1043 PF06295.12 ORY17757.1 - 0.62 10.1 3.7 0.24 11.4 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) DASH_Spc19 PF08287.11 ORY17757.1 - 5.9 6.8 11.9 0.48 10.3 5.3 2.1 2 0 0 2 2 2 0 Spc19 MFS_1 PF07690.16 ORY17758.1 - 5.8e-13 48.5 52.6 5.2e-11 42.1 22.1 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1574 PF07611.11 ORY17758.1 - 0.37 10.1 1.2 0.43 9.9 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1574) Ank_3 PF13606.6 ORY17759.1 - 0.09 13.4 0.0 0.25 12.0 0.0 1.8 1 0 0 1 1 1 0 Ankyrin repeat GOLD_2 PF13897.6 ORY17759.1 - 0.13 12.8 0.8 0.17 12.4 0.1 1.6 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking HTH_25 PF13413.6 ORY17759.1 - 0.21 11.5 0.2 28 4.7 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain SesA PF17107.5 ORY17760.1 - 8.4e-06 26.0 0.1 1e-05 25.7 0.1 1.2 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases Exo70 PF03081.15 ORY17760.1 - 0.065 12.3 0.1 0.071 12.2 0.1 1.0 1 0 0 1 1 1 0 Exo70 exocyst complex subunit Pkinase PF00069.25 ORY17761.1 - 1.1e-35 123.3 0.0 1.4e-35 122.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY17761.1 - 8.9e-26 90.7 0.0 1.1e-25 90.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 ORY17761.1 - 2.5e-05 23.7 0.2 5.1e-05 22.7 0.2 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 ORY17761.1 - 0.009 15.6 0.0 0.019 14.6 0.0 1.5 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 ORY17761.1 - 0.18 11.7 0.3 2.4 8.0 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family SLAC1 PF03595.17 ORY17762.1 - 2.7e-84 283.2 49.0 3.1e-84 283.0 49.0 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel FAT PF02259.23 ORY17763.1 - 8.7e-117 390.2 0.7 8.7e-117 390.2 0.7 1.7 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.27 ORY17763.1 - 2.4e-72 243.7 0.2 4.7e-72 242.8 0.2 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.8 ORY17763.1 - 1.2e-62 210.5 1.5 8.3e-57 191.6 0.1 6.0 4 2 1 6 6 6 1 Domain of unknown function (DUF3385) FRB_dom PF08771.11 ORY17763.1 - 1.3e-43 147.4 1.3 2.7e-42 143.2 0.0 3.3 2 0 0 2 2 2 1 FKBP12-rapamycin binding domain FATC PF02260.20 ORY17763.1 - 1.9e-17 62.8 0.1 4.6e-17 61.5 0.1 1.8 1 0 0 1 1 1 1 FATC domain HEAT_2 PF13646.6 ORY17763.1 - 1e-15 57.8 9.2 0.0094 16.3 0.0 10.2 7 2 3 10 10 10 3 HEAT repeats HEAT PF02985.22 ORY17763.1 - 6.2e-14 50.9 14.6 0.12 12.7 0.0 11.7 11 0 0 11 11 11 3 HEAT repeat HEAT_EZ PF13513.6 ORY17763.1 - 3.6e-13 49.7 13.2 0.001 19.5 0.1 11.0 8 2 3 11 11 11 2 HEAT-like repeat Cnd1 PF12717.7 ORY17763.1 - 8.9e-07 29.1 1.0 3.2 7.8 0.0 6.2 4 1 2 6 6 6 1 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 ORY17763.1 - 8.8e-06 26.2 0.0 5.6 7.6 0.0 6.1 6 0 0 6 6 5 1 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 ORY17763.1 - 1.7e-05 23.6 0.9 0.51 8.8 0.0 4.6 3 2 0 3 3 3 2 Adaptin N terminal region DUF3730 PF12530.8 ORY17763.1 - 4.1e-05 23.3 0.0 0.26 10.8 0.0 4.5 3 1 1 4 4 4 1 Protein of unknown function (DUF3730) Xpo1 PF08389.12 ORY17763.1 - 0.00043 20.4 0.0 0.25 11.4 0.0 4.9 3 3 1 4 4 4 1 Exportin 1-like protein Tti2 PF10521.9 ORY17763.1 - 0.0011 18.6 1.0 3.2 7.2 0.0 4.3 2 1 1 3 3 3 1 Tti2 family TPR_16 PF13432.6 ORY17763.1 - 0.026 15.2 0.1 32 5.3 0.0 3.9 3 0 0 3 3 2 0 Tetratricopeptide repeat ParcG PF10274.9 ORY17763.1 - 0.065 13.3 2.6 26 4.9 0.0 3.8 3 0 0 3 3 3 0 Parkin co-regulated protein TPR_19 PF14559.6 ORY17763.1 - 0.068 13.7 0.9 33 5.1 0.1 4.1 3 0 0 3 3 2 0 Tetratricopeptide repeat TAF6_C PF07571.13 ORY17763.1 - 0.072 13.4 0.0 8.6 6.8 0.0 4.2 5 0 0 5 5 2 0 TAF6 C-terminal HEAT repeat domain TPR_2 PF07719.17 ORY17763.1 - 0.12 12.5 2.0 12 6.3 0.1 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Abhydrolase_6 PF12697.7 ORY17765.1 - 2e-14 54.8 0.1 2.2e-14 54.6 0.1 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORY17765.1 - 0.0004 19.7 0.0 0.0017 17.7 0.0 1.9 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ORY17765.1 - 0.0013 18.4 0.0 0.0036 17.0 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold ABC1 PF03109.16 ORY17766.1 - 2.9e-21 75.8 0.0 8.1e-12 45.4 0.0 2.5 1 1 0 2 2 2 2 ABC1 family RIO1 PF01163.22 ORY17766.1 - 0.14 11.8 0.0 0.83 9.2 0.0 2.0 2 0 0 2 2 2 0 RIO1 family Raf1_HTH PF18579.1 ORY17766.1 - 0.15 11.8 0.0 0.32 10.7 0.0 1.5 1 0 0 1 1 1 0 Rubisco accumulation factor 1 helix turn helix domain Kelch_4 PF13418.6 ORY17767.1 - 5.7e-25 87.1 10.5 2e-07 30.9 0.1 6.3 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_6 PF13964.6 ORY17767.1 - 7.1e-23 80.1 3.2 1.2e-08 34.9 0.1 6.0 5 1 1 6 6 6 4 Kelch motif Kelch_1 PF01344.25 ORY17767.1 - 1.6e-20 72.4 0.8 7.8e-08 31.8 0.1 5.3 5 0 0 5 5 5 3 Kelch motif Kelch_3 PF13415.6 ORY17767.1 - 4e-18 65.2 8.3 7.9e-08 32.4 0.2 5.7 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_5 PF13854.6 ORY17767.1 - 2.1e-13 49.9 5.5 0.0091 16.0 0.0 6.4 7 0 0 7 7 7 4 Kelch motif Kelch_2 PF07646.15 ORY17767.1 - 2.6e-09 36.7 5.5 0.0031 17.4 0.1 5.3 6 0 0 6 6 6 3 Kelch motif TPR_10 PF13374.6 ORY17768.1 - 0.00033 20.4 3.4 0.062 13.2 0.0 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 ORY17768.1 - 0.025 15.4 7.0 19 6.4 0.5 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat RCC_reductase PF06405.11 ORY17768.1 - 0.041 13.1 0.1 0.091 11.9 0.1 1.5 1 0 0 1 1 1 0 Red chlorophyll catabolite reductase (RCC reductase) Vta1_C PF18097.1 ORY17768.1 - 0.36 10.6 6.4 1.8 8.4 0.1 4.0 4 0 0 4 4 4 0 Vta1 C-terminal domain DUF2870 PF11069.8 ORY17768.1 - 0.43 11.0 2.9 2.3 8.7 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2870) TPR_11 PF13414.6 ORY17768.1 - 6.7 6.5 7.4 9.3 6.0 0.0 4.4 6 0 0 6 6 6 0 TPR repeat TPR_12 PF13424.6 ORY17768.1 - 8 6.8 9.5 1.5 9.2 0.3 4.1 4 2 0 4 4 4 0 Tetratricopeptide repeat Pkinase PF00069.25 ORY17769.1 - 1.4e-65 221.3 0.0 2.3e-65 220.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY17769.1 - 2.7e-31 108.8 0.0 7.7e-31 107.3 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORY17769.1 - 0.024 13.5 0.0 0.04 12.7 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 ORY17769.1 - 0.064 12.6 0.0 0.5 9.6 0.0 2.0 2 0 0 2 2 2 0 Kinase-like APH PF01636.23 ORY17769.1 - 0.12 12.3 0.6 1.7 8.5 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 ORY17769.1 - 0.14 11.1 0.1 0.22 10.4 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_C PF00433.24 ORY17769.1 - 0.47 11.2 4.3 1.9 9.2 4.3 2.1 1 1 0 1 1 1 0 Protein kinase C terminal domain CFEM PF05730.11 ORY17770.1 - 9.3e-09 35.3 3.2 9.3e-09 35.3 3.2 2.0 2 0 0 2 2 2 1 CFEM domain NCA2 PF08637.10 ORY17771.1 - 8.1e-102 340.3 0.1 1.3e-101 339.6 0.1 1.3 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 Ras PF00071.22 ORY17771.1 - 2.8e-53 179.8 0.7 8.1e-53 178.3 0.1 1.9 2 0 0 2 2 2 1 Ras family Roc PF08477.13 ORY17771.1 - 5.9e-24 84.6 0.3 1.7e-23 83.1 0.2 1.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY17771.1 - 7.6e-09 35.3 0.1 1.5e-08 34.3 0.1 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 ORY17771.1 - 0.00028 20.5 0.0 0.00058 19.4 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MFS_1 PF07690.16 ORY17772.1 - 1.1e-21 77.2 33.3 1e-13 51.0 17.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY17772.1 - 5.6e-14 51.9 18.7 2.5e-13 49.7 18.7 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter AAA PF00004.29 ORY17773.1 - 1e-43 148.9 0.0 1.7e-43 148.2 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 ORY17773.1 - 9.3e-15 54.2 0.0 2.2e-14 52.9 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 ORY17773.1 - 9.7e-08 32.3 0.0 1.9e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 ORY17773.1 - 6.2e-07 29.5 0.0 1.6e-06 28.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 ORY17773.1 - 7e-07 29.8 0.0 3.9e-05 24.1 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 ORY17773.1 - 1.5e-05 25.2 0.2 0.0063 16.8 0.0 2.4 1 1 1 2 2 2 1 AAA domain Prot_ATP_ID_OB PF16450.5 ORY17773.1 - 2.1e-05 24.4 2.1 5.5e-05 23.0 2.1 1.8 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain RuvB_N PF05496.12 ORY17773.1 - 6.1e-05 22.8 0.0 0.00013 21.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 ORY17773.1 - 0.001 18.9 0.0 0.0018 18.0 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.13 ORY17773.1 - 0.0011 18.2 0.0 0.0023 17.2 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_18 PF13238.6 ORY17773.1 - 0.0017 18.9 0.0 0.028 15.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 ORY17773.1 - 0.002 18.3 0.0 0.004 17.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.11 ORY17773.1 - 0.0056 16.5 0.0 0.015 15.1 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_OB_N PF17758.1 ORY17773.1 - 0.007 16.0 0.1 0.024 14.3 0.1 2.0 1 1 0 1 1 1 1 Proteasomal ATPase OB N-terminal domain ATPase PF06745.13 ORY17773.1 - 0.0074 15.7 0.0 0.019 14.3 0.0 1.7 1 0 0 1 1 1 1 KaiC Mg_chelatase PF01078.21 ORY17773.1 - 0.008 15.6 0.1 0.017 14.5 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TsaE PF02367.17 ORY17773.1 - 0.01 15.8 0.0 0.02 14.9 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 ORY17773.1 - 0.011 15.9 0.0 0.02 15.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 ORY17773.1 - 0.019 14.1 0.0 0.035 13.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Sigma54_activat PF00158.26 ORY17773.1 - 0.021 14.6 0.0 0.092 12.4 0.0 2.0 3 0 0 3 3 2 0 Sigma-54 interaction domain PhoH PF02562.16 ORY17773.1 - 0.026 14.0 0.0 0.1 12.1 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein AAA_7 PF12775.7 ORY17773.1 - 0.028 13.9 0.0 0.047 13.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 ORY17773.1 - 0.038 14.4 0.0 0.069 13.5 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 ORY17773.1 - 0.041 13.6 0.0 0.1 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 ORY17773.1 - 0.041 13.9 0.0 0.071 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain HR1 PF02185.16 ORY17773.1 - 0.052 13.7 0.7 0.13 12.4 0.7 1.6 1 0 0 1 1 1 0 Hr1 repeat AAA_25 PF13481.6 ORY17773.1 - 0.068 12.7 0.1 0.21 11.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 ORY17773.1 - 0.09 11.9 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Zeta_toxin PF06414.12 ORY17773.1 - 0.17 11.2 0.0 0.28 10.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin DUF2072 PF09845.9 ORY17773.1 - 0.17 12.2 0.1 0.32 11.2 0.1 1.5 1 0 0 1 1 1 0 Zn-ribbon containing protein Na_Ca_ex PF01699.24 ORY17774.1 - 3.9e-20 72.3 37.7 2.8e-14 53.3 13.1 4.2 5 2 1 6 6 6 2 Sodium/calcium exchanger protein YccF PF03733.13 ORY17774.1 - 7.6e-15 55.4 12.5 7.6e-15 55.4 12.5 4.8 5 0 0 5 5 5 1 Inner membrane component domain TFIIA PF03153.13 ORY17774.1 - 0.0045 17.0 5.5 0.0045 17.0 5.5 2.0 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit zf-RING_2 PF13639.6 ORY17775.1 - 2.5e-13 50.1 4.5 4e-13 49.5 4.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 ORY17775.1 - 2.1e-11 43.3 1.9 3.5e-11 42.6 1.9 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 ORY17775.1 - 2.2e-08 33.8 4.6 3.4e-08 33.2 4.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORY17775.1 - 3.8e-07 29.9 3.6 6e-07 29.2 3.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 ORY17775.1 - 2e-06 28.0 4.8 4.9e-06 26.7 4.8 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 ORY17775.1 - 2.8e-05 23.9 4.9 4.9e-05 23.1 4.9 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 ORY17775.1 - 3.2e-05 23.8 2.1 5e-05 23.2 2.1 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 ORY17775.1 - 0.00053 19.8 1.1 0.00088 19.1 1.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 ORY17775.1 - 0.0042 17.1 0.8 0.0079 16.2 0.8 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 ORY17775.1 - 0.027 14.3 3.3 0.049 13.4 3.3 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.6 ORY17775.1 - 0.029 14.4 6.4 0.056 13.5 6.4 1.5 1 0 0 1 1 1 0 RING-type zinc-finger Prok-RING_1 PF14446.6 ORY17775.1 - 0.25 11.3 3.5 0.23 11.4 1.3 1.8 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 PHD PF00628.29 ORY17775.1 - 0.3 11.0 3.1 0.53 10.2 3.1 1.4 1 0 0 1 1 1 0 PHD-finger zf-RING-like PF08746.11 ORY17775.1 - 0.35 11.2 2.1 0.6 10.5 2.1 1.4 1 0 0 1 1 1 0 RING-like domain FANCL_C PF11793.8 ORY17775.1 - 2.4 8.4 4.0 13 6.0 4.0 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain F-box-like PF12937.7 ORY17776.1 - 0.00046 20.0 0.5 0.0018 18.2 0.1 2.2 2 0 0 2 2 2 1 F-box-like F-box_4 PF15966.5 ORY17776.1 - 0.12 12.2 0.5 3.8 7.4 0.0 2.7 2 0 0 2 2 2 0 F-box DUF3292 PF11696.8 ORY17777.1 - 4.4e-292 970.3 0.0 5.9e-292 969.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3292) IGR PF09597.10 ORY17777.1 - 0.095 12.8 0.1 0.99 9.6 0.0 2.3 2 0 0 2 2 2 0 IGR protein motif HET PF06985.11 ORY17778.1 - 1.1e-07 32.3 0.0 1.2e-07 32.2 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Kinesin PF00225.23 ORY17779.1 - 1.3e-61 208.4 0.0 2.2e-61 207.6 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 ORY17779.1 - 1.1e-10 41.7 0.8 6.5e-08 32.6 0.0 3.2 3 0 0 3 3 3 2 Microtubule binding ORC3_N PF07034.11 ORY17779.1 - 0.087 11.9 1.9 0.15 11.1 1.9 1.3 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 3 N-terminus Mto2_bdg PF12808.7 ORY17779.1 - 0.53 10.6 8.4 0.064 13.6 1.2 2.8 3 0 0 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region DUF87 PF01935.17 ORY17779.1 - 9.1 6.3 8.1 5.3 7.1 0.5 3.2 3 1 0 3 3 3 0 Helicase HerA, central domain His_Phos_2 PF00328.22 ORY17780.1 - 2.9e-105 352.8 0.2 3.9e-105 352.3 0.2 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 ORY17780.1 - 2.3e-34 117.4 0.0 5e-34 116.3 0.0 1.5 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 ORY17780.1 - 0.00025 20.7 0.0 0.00043 19.9 0.0 1.2 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Utp21 PF04192.12 ORY17781.1 - 5.1e-75 252.0 0.0 7.1e-75 251.5 0.0 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.32 ORY17781.1 - 1.1e-14 54.6 27.1 0.00058 20.6 0.5 9.8 11 0 0 11 11 11 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY17781.1 - 1.6e-13 50.8 0.0 0.00088 19.5 0.0 5.7 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 ORY17781.1 - 0.00044 18.9 0.0 0.00085 18.0 0.0 1.5 1 0 0 1 1 1 1 Cytochrome D1 heme domain Nucleoporin_N PF08801.11 ORY17781.1 - 0.033 12.9 0.4 5.6 5.6 0.2 2.3 1 1 1 2 2 2 0 Nup133 N terminal like Utp8 PF10395.9 ORY17781.1 - 0.29 9.6 0.0 0.43 9.0 0.0 1.2 1 0 0 1 1 1 0 Utp8 family Fungal_trans_2 PF11951.8 ORY17782.1 - 2e-14 53.2 3.9 3.2e-13 49.2 3.9 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain CAP_N PF01213.19 ORY17783.1 - 0.12 11.9 2.6 0.89 9.0 0.2 2.1 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal BUD22 PF09073.10 ORY17783.1 - 0.55 9.5 10.3 0.68 9.2 10.3 1.1 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 ORY17783.1 - 6.6 6.1 12.7 9 5.6 12.7 1.2 1 0 0 1 1 1 0 SDA1 DNA_pol_phi PF04931.13 ORY17783.1 - 6.9 4.6 15.1 9.3 4.2 15.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi TFIIB PF00382.19 ORY17786.1 - 6.9e-33 112.5 1.7 3.3e-19 68.7 0.1 2.5 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.13 ORY17786.1 - 1.1e-22 80.3 0.9 1.1e-22 80.3 0.9 3.3 2 1 0 2 2 2 1 Brf1-like TBP-binding domain DUF348 PF03990.14 ORY17786.1 - 0.061 13.1 0.0 6.9 6.5 0.0 2.9 2 0 0 2 2 2 0 G5-linked-Ubiquitin-like domain Fic PF02661.18 ORY17786.1 - 0.25 12.2 0.7 36 5.4 0.0 3.7 4 0 0 4 4 4 0 Fic/DOC family PHD PF00628.29 ORY17787.1 - 1.6e-10 40.7 7.0 2.6e-10 40.0 7.0 1.3 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.6 ORY17787.1 - 0.002 18.0 5.4 0.0038 17.1 5.4 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 C1_1 PF00130.22 ORY17787.1 - 0.0044 16.9 1.6 0.0081 16.0 1.6 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RRPl_C4 PF17026.5 ORY17787.1 - 0.0064 16.6 0.7 0.01 15.9 0.7 1.2 1 0 0 1 1 1 1 Putative ribonucleoprotein zinc-finger pf C4 type zf-PHD-like PF15446.6 ORY17787.1 - 0.0071 16.0 2.7 0.014 15.0 2.7 1.5 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain PHD_2 PF13831.6 ORY17787.1 - 0.072 12.7 7.1 0.21 11.2 7.1 1.8 1 1 0 1 1 1 0 PHD-finger FYVE_2 PF02318.16 ORY17787.1 - 0.42 10.8 2.4 0.73 10.1 2.4 1.3 1 0 0 1 1 1 0 FYVE-type zinc finger CoA_transf_3 PF02515.17 ORY17788.1 - 4.2e-122 407.8 0.0 4.8e-122 407.6 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III Lum_binding PF00677.17 ORY17789.1 - 4e-45 151.7 0.6 6.1e-22 77.4 0.2 2.2 2 0 0 2 2 2 2 Lumazine binding domain PrcB_C PF14343.6 ORY17789.1 - 0.097 12.8 0.1 3.4 7.9 0.1 2.8 2 1 1 3 3 3 0 PrcB C-terminal PrmA PF06325.13 ORY17791.1 - 6.8e-11 42.1 0.0 1.1e-10 41.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 ORY17791.1 - 1.2e-10 41.3 0.1 2e-10 40.7 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY17791.1 - 2.4e-10 41.0 0.0 4.7e-10 40.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY17791.1 - 1.2e-06 29.1 0.0 2.3e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 ORY17791.1 - 9.2e-06 24.8 0.1 1.4e-05 24.2 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_18 PF12847.7 ORY17791.1 - 9.9e-06 25.6 0.2 1.9e-05 24.6 0.2 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY17791.1 - 0.00011 22.1 0.0 0.00018 21.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 ORY17791.1 - 0.0005 19.4 0.0 0.00069 19.0 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 ORY17791.1 - 0.0055 16.3 0.1 0.0096 15.5 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 ORY17791.1 - 0.026 15.3 0.0 0.045 14.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.6 ORY17791.1 - 0.091 12.7 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PRMT5 PF05185.16 ORY17791.1 - 0.14 12.0 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase AA_permease_2 PF13520.6 ORY17794.1 - 6.5e-43 147.1 37.9 8.4e-43 146.8 37.9 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ORY17794.1 - 1.3e-24 86.6 24.4 1.3e-24 86.6 24.4 2.0 2 0 0 2 2 2 2 Amino acid permease Fer4_12 PF13353.6 ORY17795.1 - 0.00014 22.1 0.0 0.00026 21.3 0.0 1.3 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 ORY17795.1 - 0.00056 20.0 0.0 0.00091 19.3 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Radical_SAM PF04055.21 ORY17795.1 - 0.0096 16.3 0.0 0.016 15.6 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily 2OG-FeII_Oxy PF03171.20 ORY17796.1 - 2.5e-09 37.5 0.1 3.4e-08 33.9 0.0 2.2 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 ORY17796.1 - 5.6e-05 23.9 0.0 0.00011 22.9 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal bZIP_1 PF00170.21 ORY17797.1 - 0.0017 18.4 15.2 0.0036 17.4 15.2 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 ORY17797.1 - 0.0021 18.6 11.0 0.0021 18.6 11.0 2.0 2 0 0 2 2 2 1 bZIP Maf transcription factor bZIP_2 PF07716.15 ORY17797.1 - 0.008 16.2 17.6 0.019 15.0 17.6 1.7 1 0 0 1 1 1 1 Basic region leucine zipper CENP-Q PF13094.6 ORY17797.1 - 5.4 7.2 14.1 13 5.9 14.1 1.9 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DAO PF01266.24 ORY17799.1 - 3.2e-49 168.4 0.1 3.7e-49 168.2 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ORY17799.1 - 0.00032 20.9 0.0 0.00081 19.6 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain MCRA PF06100.11 ORY17799.1 - 0.0025 16.7 0.0 0.0033 16.3 0.0 1.1 1 0 0 1 1 1 1 MCRA family Pyr_redox PF00070.27 ORY17799.1 - 0.038 14.5 0.0 4.2 8.0 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ORY17799.1 - 0.16 12.0 0.0 0.38 10.7 0.0 1.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding Thi4 PF01946.17 ORY17799.1 - 0.16 11.2 0.0 0.27 10.4 0.0 1.3 1 0 0 1 1 1 0 Thi4 family CRC_subunit PF08624.10 ORY17801.1 - 4.4e-53 179.3 0.1 6.2e-53 178.8 0.1 1.2 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit DUF5050 PF16472.5 ORY17801.1 - 0.0043 16.3 0.0 0.0064 15.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF5050) Pkinase PF00069.25 ORY17802.1 - 2.3e-39 135.4 0.1 8.9e-23 81.0 0.1 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORY17802.1 - 1.1e-15 57.7 0.2 4.7e-10 39.2 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORY17802.1 - 0.068 11.9 0.1 0.1 11.3 0.1 1.4 1 0 0 1 1 1 0 Fungal protein kinase Keratin_assoc PF09775.9 ORY17803.1 - 0.014 15.1 0.2 0.023 14.4 0.2 1.2 1 0 0 1 1 1 0 Keratinocyte-associated protein 2 ATG16 PF08614.11 ORY17804.1 - 1.2e-06 29.0 169.7 0.019 15.2 12.8 7.7 1 1 6 7 7 7 6 Autophagy protein 16 (ATG16) Spc7 PF08317.11 ORY17804.1 - 0.00023 20.2 158.8 0.028 13.3 24.0 8.3 2 2 5 8 8 8 5 Spc7 kinetochore protein FPP PF05911.11 ORY17804.1 - 0.0014 16.9 140.2 0.022 13.0 23.8 6.0 1 1 5 6 6 6 4 Filament-like plant protein, long coiled-coil Tropomyosin PF00261.20 ORY17804.1 - 0.0027 17.1 43.9 0.0027 17.1 43.9 5.5 2 2 3 5 5 3 2 Tropomyosin CENP-H PF05837.12 ORY17804.1 - 0.0096 16.3 12.2 0.0096 16.3 12.2 10.8 2 2 8 10 10 9 1 Centromere protein H (CENP-H) Filament PF00038.21 ORY17804.1 - 0.01 15.5 139.1 0.0071 16.0 31.4 8.3 2 2 3 7 7 7 0 Intermediate filament protein CENP-F_leu_zip PF10473.9 ORY17804.1 - 0.011 15.8 20.5 0.011 15.8 20.5 9.9 2 2 7 9 9 8 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Cep57_MT_bd PF06657.13 ORY17804.1 - 0.019 15.4 1.3 0.019 15.4 1.3 11.5 7 4 6 13 13 11 0 Centrosome microtubule-binding domain of Cep57 Cob_adeno_trans PF01923.18 ORY17804.1 - 0.019 15.1 1.3 0.019 15.1 1.3 8.0 2 2 5 7 7 6 0 Cobalamin adenosyltransferase Lipocalin_8 PF16585.5 ORY17804.1 - 0.18 12.3 4.9 0.11 13.0 0.8 2.9 2 0 0 2 2 2 0 Lipocalin-like domain GAS PF13851.6 ORY17804.1 - 0.25 10.6 150.4 0.21 10.9 21.4 10.1 2 2 7 10 10 10 0 Growth-arrest specific micro-tubule binding HMMR_N PF15905.5 ORY17804.1 - 0.45 9.9 148.6 0.019 14.4 22.9 7.0 2 2 5 7 7 7 0 Hyaluronan mediated motility receptor N-terminal DUF1843 PF08898.10 ORY17804.1 - 0.55 10.8 0.1 0.55 10.8 0.1 8.9 11 0 0 11 11 9 0 Domain of unknown function (DUF1843) Fib_alpha PF08702.10 ORY17804.1 - 1.1 9.4 100.8 1.5 9.0 10.4 9.4 3 2 6 9 9 9 0 Fibrinogen alpha/beta chain family Fez1 PF06818.15 ORY17804.1 - 1.9 8.9 149.0 0.24 11.8 24.7 7.8 1 1 6 7 7 7 0 Fez1 Trans_reg_C PF00486.28 ORY17804.1 - 5.2 7.2 11.6 25 5.0 0.1 5.3 5 0 0 5 5 5 0 Transcriptional regulatory protein, C terminal DUF745 PF05335.13 ORY17804.1 - 6.9 6.3 121.4 0.012 15.3 10.3 8.0 4 2 4 8 8 8 0 Protein of unknown function (DUF745) RAC_head PF16717.5 ORY17805.1 - 1.7e-31 109.1 5.5 1.7e-31 109.1 5.5 3.3 3 1 0 3 3 3 1 Ribosome-associated complex head domain DnaJ PF00226.31 ORY17805.1 - 6.5e-21 74.2 1.3 2.6e-20 72.3 1.3 2.1 1 0 0 1 1 1 1 DnaJ domain V_ATPase_I PF01496.19 ORY17805.1 - 0.83 7.5 10.8 1.5 6.7 10.8 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Usp PF00582.26 ORY17806.1 - 7.3e-24 84.9 0.1 3.2e-23 82.8 0.0 2.0 2 0 0 2 2 2 1 Universal stress protein family ABA_GPCR PF12430.8 ORY17807.1 - 4.4e-55 186.2 6.5 4.4e-55 186.2 6.5 2.1 2 0 0 2 2 2 1 Abscisic acid G-protein coupled receptor GPHR_N PF12537.8 ORY17807.1 - 3.2e-22 78.4 3.2 3.3e-22 78.3 0.2 2.6 3 0 0 3 3 3 1 The Golgi pH Regulator (GPHR) Family N-terminal LRR_4 PF12799.7 ORY17809.1 - 0.021 15.3 3.3 23 5.6 0.1 4.3 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) Transket_pyr PF02779.24 ORY17810.1 - 1e-47 162.1 0.0 1.7e-47 161.4 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 ORY17810.1 - 5.5e-34 116.7 0.0 1.4e-33 115.4 0.0 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain Sterol_MT_C PF08498.10 ORY17811.1 - 1.5e-30 105.3 0.2 2.5e-30 104.5 0.2 1.4 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 ORY17811.1 - 3.8e-19 69.1 0.0 7.2e-19 68.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY17811.1 - 2e-18 66.9 0.0 4.2e-18 65.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY17811.1 - 2.6e-17 63.0 0.0 3.8e-17 62.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY17811.1 - 2.4e-12 47.0 0.0 4.3e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 ORY17811.1 - 4e-12 46.0 0.0 5.7e-12 45.5 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 ORY17811.1 - 8.2e-10 39.3 0.0 2.1e-09 38.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORY17811.1 - 9.3e-09 35.0 0.0 1.7e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 ORY17811.1 - 0.00013 21.7 0.0 0.00023 21.0 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 ORY17811.1 - 0.00087 18.8 0.0 0.0027 17.2 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_15 PF09445.10 ORY17811.1 - 0.0013 18.3 0.0 0.0021 17.6 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_29 PF03141.16 ORY17811.1 - 0.0021 16.7 0.0 0.0032 16.1 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase MTS PF05175.14 ORY17811.1 - 0.0073 15.9 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.18 ORY17811.1 - 0.014 14.7 0.0 0.038 13.3 0.0 1.8 2 0 0 2 2 2 0 O-methyltransferase domain Methyltransf_32 PF13679.6 ORY17811.1 - 0.022 14.8 0.8 0.059 13.4 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain RrnaAD PF00398.20 ORY17811.1 - 0.024 13.7 0.0 0.035 13.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase TehB PF03848.14 ORY17811.1 - 0.045 13.2 0.1 0.11 11.9 0.0 1.7 2 0 0 2 2 2 0 Tellurite resistance protein TehB UPF0020 PF01170.18 ORY17811.1 - 0.1 12.3 0.0 0.23 11.1 0.0 1.6 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 RRP14 PF15459.6 ORY17811.1 - 0.34 11.5 3.6 0.82 10.3 3.6 1.6 1 0 0 1 1 1 0 60S ribosome biogenesis protein Rrp14 RRM_1 PF00076.22 ORY17812.1 - 1.7e-08 34.1 0.0 2.8e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 ORY17812.1 - 0.00018 21.5 0.0 0.00035 20.5 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 ORY17812.1 - 0.0026 17.7 0.1 0.0083 16.2 0.0 1.8 2 0 0 2 2 2 1 RNA binding motif RRM_occluded PF16842.5 ORY17812.1 - 0.021 14.6 0.0 0.035 14.0 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif Complex1_LYR PF05347.15 ORY17813.1 - 0.00045 20.2 0.7 0.0012 18.8 0.7 1.8 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Phage_ABA_S PF18066.1 ORY17813.1 - 0.03 15.0 0.0 0.033 14.9 0.0 1.1 1 0 0 1 1 1 0 Phage ABA sandwich domain Complex1_LYR_2 PF13233.6 ORY17813.1 - 0.034 14.9 0.4 0.044 14.5 0.4 1.3 1 0 0 1 1 1 0 Complex1_LYR-like zinc_ribbon_10 PF10058.9 ORY17814.1 - 2.2e-20 72.1 0.1 3.9e-20 71.3 0.1 1.4 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein DUF4551 PF15087.6 ORY17816.1 - 7.5 5.2 8.7 12 4.6 8.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Amidase PF01425.21 ORY17818.1 - 2.3e-70 237.8 0.0 3e-70 237.4 0.0 1.1 1 0 0 1 1 1 1 Amidase Isochorismatase PF00857.20 ORY17818.1 - 5.1e-35 121.2 0.0 7.4e-34 117.4 0.0 2.3 2 0 0 2 2 2 1 Isochorismatase family Transp_cyt_pur PF02133.15 ORY17819.1 - 8.2e-80 268.7 35.1 9.5e-80 268.5 35.1 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Fungal_trans PF04082.18 ORY17820.1 - 1e-24 87.0 0.2 1.6e-24 86.4 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY17820.1 - 6.4e-06 26.2 8.7 1.3e-05 25.3 8.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Folate_carrier PF01770.18 ORY17820.1 - 0.14 10.8 0.0 0.21 10.3 0.0 1.1 1 0 0 1 1 1 0 Reduced folate carrier Actin PF00022.19 ORY17821.1 - 4.1e-24 85.0 0.0 6.3e-14 51.4 0.0 2.5 2 1 0 2 2 2 2 Actin Actin_micro PF17003.5 ORY17821.1 - 9.3e-05 21.8 0.0 0.017 14.4 0.0 2.5 3 0 0 3 3 3 2 Putative actin-like family MreB_Mbl PF06723.13 ORY17821.1 - 0.0012 17.7 0.0 0.0071 15.2 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 ORY17821.1 - 0.15 12.5 0.0 0.36 11.3 0.0 1.8 1 0 0 1 1 1 0 Cell division protein FtsA Paf1 PF03985.13 ORY17822.1 - 7.9e-64 216.2 0.0 5.5e-63 213.4 0.0 1.9 1 1 0 1 1 1 1 Paf1 ATP_sub_h PF10775.9 ORY17822.1 - 0.0039 17.2 1.4 1.5 8.8 0.0 2.6 2 0 0 2 2 2 2 ATP synthase complex subunit h HET PF06985.11 ORY17823.1 - 4.8e-10 40.0 0.0 1e-09 38.9 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Anoctamin PF04547.12 ORY17824.1 - 5.3e-113 378.2 1.4 6.3e-113 378.0 1.4 1.0 1 0 0 1 1 1 1 Calcium-activated chloride channel DUF373 PF04123.13 ORY17824.1 - 3.1 7.2 5.9 0.18 11.2 0.8 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF373) Peptidase_M16_M PF16187.5 ORY17825.1 - 6.8e-46 156.8 0.5 1.2e-45 156.0 0.5 1.5 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 ORY17825.1 - 8.8e-07 29.0 0.0 1.7e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 ORY17825.1 - 0.013 15.5 0.0 2.4 8.1 0.0 2.4 1 1 1 2 2 2 0 Peptidase M16 inactive domain Transp_cyt_pur PF02133.15 ORY17826.1 - 2.4e-20 72.7 12.4 1.2e-18 67.1 12.4 2.0 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin EF-hand_1 PF00036.32 ORY17827.1 - 0.0034 16.8 0.0 0.0071 15.8 0.0 1.5 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 ORY17827.1 - 0.018 15.5 0.0 0.026 15.0 0.0 1.3 1 0 0 1 1 1 0 EF-hand domain pair Diedel PF13164.6 ORY17827.1 - 0.12 12.8 12.4 0.32 11.5 12.5 1.8 1 1 0 1 1 1 0 Diedel HET PF06985.11 ORY17828.1 - 4.3e-35 121.2 4.5 5.5e-35 120.9 4.5 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) TPR_10 PF13374.6 ORY17830.1 - 1.1e-101 330.3 5.6 4.2e-13 48.7 0.1 9.6 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_12 PF13424.6 ORY17830.1 - 5.8e-79 260.4 13.4 7e-17 61.5 0.2 9.3 3 1 7 10 10 9 9 Tetratricopeptide repeat TPR_7 PF13176.6 ORY17830.1 - 7.8e-26 88.2 7.7 0.019 14.9 0.0 8.5 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_19 PF14559.6 ORY17830.1 - 3e-15 56.5 0.0 0.012 16.1 0.0 7.0 3 2 4 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.6 ORY17830.1 - 1.3e-14 53.1 12.1 0.36 11.1 0.0 9.3 9 0 0 9 9 9 3 Tetratricopeptide repeat Clr5 PF14420.6 ORY17830.1 - 1.6e-14 53.9 0.1 6.3e-14 51.9 0.1 2.1 1 0 0 1 1 1 1 Clr5 domain TPR_16 PF13432.6 ORY17830.1 - 4.9e-13 49.5 0.1 0.0025 18.4 0.5 7.4 7 1 0 7 7 7 1 Tetratricopeptide repeat TPR_2 PF07719.17 ORY17830.1 - 1.5e-12 46.6 9.7 2.7 8.3 0.0 8.6 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_1 PF00515.28 ORY17830.1 - 2.4e-11 42.9 5.4 0.68 9.9 0.0 8.3 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_4 PF07721.14 ORY17830.1 - 4.1e-11 42.4 2.3 0.97 10.3 0.2 7.5 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_17 PF13431.6 ORY17830.1 - 2.3e-10 40.1 8.5 3.4 8.3 0.0 7.9 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_MalT PF17874.1 ORY17830.1 - 1.4e-09 37.8 5.4 2e-06 27.5 0.5 3.4 1 1 2 3 3 3 3 MalT-like TPR region TPR_14 PF13428.6 ORY17830.1 - 4.1e-06 27.2 11.7 0.32 11.9 0.0 7.8 8 1 1 9 9 8 2 Tetratricopeptide repeat TPR_20 PF14561.6 ORY17830.1 - 6.7e-05 23.2 0.0 11 6.4 0.0 5.2 4 2 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY17830.1 - 7.9e-05 22.8 0.0 0.64 10.3 0.0 5.3 4 2 3 7 7 7 2 Anaphase-promoting complex, cyclosome, subunit 3 PPR PF01535.20 ORY17830.1 - 0.00014 21.9 3.4 3.1 8.3 0.0 7.0 8 0 0 8 8 7 1 PPR repeat TPR_6 PF13174.6 ORY17830.1 - 0.0017 18.9 11.6 20 6.1 0.1 7.0 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF1897 PF09005.10 ORY17830.1 - 0.004 16.6 3.3 5.3 6.6 0.1 4.6 5 0 0 5 5 5 1 Domain of unknown function (DUF1897) DUF2664 PF10867.8 ORY17830.1 - 0.0057 17.1 0.9 75 3.9 0.0 5.4 6 0 0 6 6 6 0 Protein of unknown function (DUF2664) HAD_SAK_1 PF10307.9 ORY17830.1 - 0.012 15.5 4.0 2.5 7.9 0.2 2.9 2 2 1 3 3 3 0 HAD domain family 1 in Swiss Army Knife RNA repair proteins TetR_C_20 PF17925.1 ORY17830.1 - 0.023 15.0 1.2 8.4 6.8 0.0 4.0 1 1 2 4 4 4 0 Tetracyclin repressor-like, C-terminal domain RPN6_N PF18055.1 ORY17830.1 - 0.027 14.8 0.3 19 5.7 0.0 3.5 3 0 0 3 3 3 0 26S proteasome regulatory subunit RPN6 N-terminal domain Foie-gras_1 PF11817.8 ORY17830.1 - 0.046 13.3 0.2 7.3 6.1 0.1 2.7 2 0 0 2 2 2 0 Foie gras liver health family 1 Granin PF01271.17 ORY17830.1 - 0.15 10.9 6.6 2.5 6.9 0.1 3.4 1 1 3 4 4 4 0 Granin (chromogranin or secretogranin) HET PF06985.11 ORY17831.1 - 7.2e-30 104.3 0.1 1.6e-29 103.1 0.1 1.6 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Amidase PF01425.21 ORY17832.1 - 1.7e-112 376.7 0.1 2.1e-112 376.4 0.1 1.0 1 0 0 1 1 1 1 Amidase Pex24p PF06398.11 ORY17834.1 - 3.6e-97 325.6 0.1 4.6e-97 325.3 0.1 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Pam16 PF03656.13 ORY17835.1 - 3.3e-30 104.7 0.8 3.8e-30 104.5 0.8 1.0 1 0 0 1 1 1 1 Pam16 PAP_assoc PF03828.19 ORY17836.1 - 5.9e-10 39.2 0.0 1.2e-09 38.2 0.0 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 ORY17836.1 - 1.8e-09 37.7 0.0 4e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain RicinB_lectin_2 PF14200.6 ORY17837.1 - 7.7e-06 26.6 4.3 0.00086 20.0 0.3 2.4 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain-like HSP70 PF00012.20 ORY17838.1 - 0.00077 17.8 0.5 0.19 9.9 0.0 2.3 3 0 0 3 3 3 2 Hsp70 protein RuvX PF03652.15 ORY17838.1 - 0.015 15.7 0.0 0.15 12.5 0.0 2.3 2 0 0 2 2 2 0 Holliday junction resolvase Pilus_CpaD PF09476.10 ORY17838.1 - 0.093 12.5 0.0 1.4 8.6 0.0 2.2 2 0 0 2 2 2 0 Pilus biogenesis CpaD protein (pilus_cpaD) Recep_L_domain PF01030.24 ORY17843.1 - 5.8e-05 23.2 0.2 0.57 10.3 0.0 3.6 1 1 2 3 3 3 2 Receptor L domain SKG6 PF08693.10 ORY17843.1 - 0.00093 18.6 0.4 0.0017 17.7 0.4 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain LRR_5 PF13306.6 ORY17843.1 - 0.014 15.4 1.4 0.084 12.8 0.1 2.3 2 0 0 2 2 2 0 BspA type Leucine rich repeat region (6 copies) TMEM154 PF15102.6 ORY17843.1 - 0.022 14.6 0.0 0.045 13.7 0.0 1.4 1 0 0 1 1 1 0 TMEM154 protein family DUF4820 PF16091.5 ORY17844.1 - 7.3 5.9 7.0 0.81 9.0 0.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) PRKCSH-like PF12999.7 ORY17845.1 - 1.2e-41 142.4 7.1 1.7e-25 89.9 0.3 2.6 3 0 0 3 3 3 2 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 ORY17845.1 - 1.4e-31 109.3 2.1 1.1e-30 106.4 0.2 2.3 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 ORY17845.1 - 1e-08 36.0 0.8 1e-08 36.0 0.8 2.4 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein Fib_alpha PF08702.10 ORY17845.1 - 0.011 15.9 6.8 0.41 10.8 0.6 2.6 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family CdvA PF18822.1 ORY17845.1 - 0.12 12.2 6.1 0.73 9.7 1.8 2.5 2 0 0 2 2 2 0 CdvA-like coiled-coil domain Peripla_BP_2 PF01497.18 ORY17845.1 - 0.13 11.8 0.7 0.32 10.5 0.3 1.8 1 1 1 2 2 2 0 Periplasmic binding protein Syntaxin-6_N PF09177.11 ORY17845.1 - 0.73 10.4 7.5 17 6.1 0.4 3.3 3 0 0 3 3 3 0 Syntaxin 6, N-terminal Spc24 PF08286.11 ORY17845.1 - 0.79 10.0 4.8 29 5.0 0.1 3.3 3 0 0 3 3 3 0 Spc24 subunit of Ndc80 Nop16 PF09420.10 ORY17845.1 - 1.4 9.0 10.3 0.16 12.0 6.1 1.6 2 0 0 2 2 2 0 Ribosome biogenesis protein Nop16 Mod_r PF07200.13 ORY17845.1 - 1.6 8.8 5.5 11 6.1 0.1 3.0 2 1 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein APG6_N PF17675.1 ORY17845.1 - 3.9 8.0 16.0 11 6.5 0.2 3.7 3 1 0 3 3 3 0 Apg6 coiled-coil region Phage_GP20 PF06810.11 ORY17845.1 - 6.4 6.6 14.8 0.53 10.1 0.7 2.8 3 0 0 3 3 3 0 Phage minor structural protein GP20 YscO PF07321.12 ORY17845.1 - 7.1 6.6 17.5 47 3.9 0.2 3.2 2 1 0 2 2 2 0 Type III secretion protein YscO DUF1664 PF07889.12 ORY17845.1 - 9.9 6.2 6.7 23 5.1 0.4 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) TBCC_N PF16752.5 ORY17846.1 - 0.021 15.3 1.3 0.021 15.3 1.3 3.0 3 0 0 3 3 3 0 Tubulin-specific chaperone C N-terminal domain CFEM PF05730.11 ORY17847.1 - 2.2e-14 53.3 12.4 3.9e-14 52.5 12.4 1.4 1 0 0 1 1 1 1 CFEM domain Sulfatase PF00884.23 ORY17847.1 - 0.29 10.5 0.7 0.33 10.3 0.7 1.1 1 0 0 1 1 1 0 Sulfatase IATP PF04568.12 ORY17847.1 - 3.5 8.1 4.9 7.3 7.1 4.9 1.5 1 0 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP GCIP PF13324.6 ORY17848.1 - 1.6e-27 96.8 0.0 2.6e-27 96.1 0.0 1.3 1 0 0 1 1 1 1 Grap2 and cyclin-D-interacting Phytase-like PF13449.6 ORY17849.1 - 1.4e-38 133.5 0.1 2.8e-38 132.5 0.1 1.5 1 1 0 1 1 1 1 Esterase-like activity of phytase TRI12 PF06609.13 ORY17850.1 - 5.9e-84 282.6 23.8 7.8e-84 282.2 23.8 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 ORY17850.1 - 2.8e-23 82.4 57.4 4.7e-22 78.4 52.7 3.1 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY17850.1 - 1.4e-09 37.4 8.3 1.4e-09 37.4 8.3 3.6 3 1 0 4 4 4 1 Sugar (and other) transporter Pox_A14 PF05767.12 ORY17850.1 - 0.0023 18.1 1.0 0.0023 18.1 1.0 3.2 4 0 0 4 4 4 1 Poxvirus virion envelope protein A14 DUF2735 PF10931.8 ORY17851.1 - 0.16 12.7 0.4 3.4 8.4 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2735) DUF3328 PF11807.8 ORY17852.1 - 1.1e-21 77.6 0.0 1.6e-21 77.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) UPF0370 PF13980.6 ORY17852.1 - 0.055 13.5 0.2 0.14 12.2 0.2 1.8 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0370) p450 PF00067.22 ORY17853.1 - 4.2e-59 200.5 0.0 5.6e-59 200.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Brr6_like_C_C PF10104.9 ORY17854.1 - 1.3e-40 138.2 2.3 1.7e-40 137.8 2.3 1.1 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain STIMATE PF12400.8 ORY17854.1 - 0.034 14.7 0.1 0.071 13.7 0.1 1.5 1 1 0 1 1 1 0 STIMATE family Connexin PF00029.19 ORY17854.1 - 0.12 12.2 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Connexin CDC45 PF02724.14 ORY17854.1 - 0.23 9.7 1.8 0.31 9.3 1.8 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF1729 PF08354.10 ORY17855.1 - 5.5e-159 528.8 0.0 8.6e-159 528.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) Acyl_transf_1 PF00698.21 ORY17855.1 - 4.3e-91 305.7 0.1 1.2e-89 300.9 0.0 3.2 4 0 0 4 4 4 1 Acyl transferase domain FAS_meander PF17951.1 ORY17855.1 - 1.7e-53 180.4 0.0 4.1e-53 179.1 0.0 1.7 1 0 0 1 1 1 1 Fatty acid synthase meander beta sheet domain SAT PF16073.5 ORY17855.1 - 8.4e-38 130.4 0.0 2.3e-37 129.0 0.0 1.8 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis FAS_N PF17828.1 ORY17855.1 - 2.2e-37 127.9 0.0 5.9e-37 126.6 0.0 1.8 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta MaoC_dehydratas PF01575.19 ORY17855.1 - 2.1e-36 124.2 0.0 4.2e-36 123.2 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 ORY17855.1 - 6.6e-23 81.3 0.0 2.1e-22 79.7 0.0 1.9 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase FAS_I_H PF18314.1 ORY17856.1 - 7.4e-80 267.4 0.0 1.4e-79 266.4 0.0 1.5 1 0 0 1 1 1 1 Fatty acid synthase type I helical domain Fas_alpha_ACP PF18325.1 ORY17856.1 - 7.4e-76 254.0 0.0 1.9e-75 252.6 0.0 1.8 1 0 0 1 1 1 1 Fatty acid synthase subunit alpha Acyl carrier domain ketoacyl-synt PF00109.26 ORY17856.1 - 9.8e-21 74.5 0.0 2.1e-20 73.4 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACPS PF01648.20 ORY17856.1 - 1.5e-17 63.8 0.1 3.5e-17 62.6 0.1 1.6 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.22 ORY17856.1 - 2.5e-10 40.4 0.0 6.9e-10 39.0 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.25 ORY17856.1 - 7.6e-07 28.8 0.0 3.2e-06 26.7 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 ORY17856.1 - 0.0068 16.3 0.0 0.025 14.5 0.0 2.0 2 0 0 2 2 2 1 KR domain DUF1031 PF06275.11 ORY17856.1 - 0.13 12.5 0.2 1.3 9.3 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1031) adh_short PF00106.25 ORY17857.1 - 6.4e-38 130.2 0.1 9e-38 129.7 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY17857.1 - 3.3e-24 85.8 0.0 4.3e-24 85.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY17857.1 - 4.8e-11 42.9 0.0 8.8e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 ORY17857.1 - 0.0015 18.0 0.0 0.0021 17.5 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 ORY17857.1 - 0.0022 17.5 0.0 0.0031 17.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Fungal_trans PF04082.18 ORY17859.1 - 8.5e-08 31.5 0.1 1.5e-07 30.7 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY17859.1 - 4.4e-06 26.7 9.5 8.5e-06 25.8 9.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain IDO PF01231.18 ORY17860.1 - 7.6e-142 473.1 0.0 9.1e-142 472.8 0.0 1.1 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase DUF1864 PF08933.11 ORY17860.1 - 0.052 12.3 0.1 0.17 10.6 0.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF1864) Aminotran_5 PF00266.19 ORY17861.1 - 1.4e-05 24.2 0.0 4.1e-05 22.7 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class-V ketoacyl-synt PF00109.26 ORY17862.1 - 2.2e-68 230.6 0.2 3.8e-68 229.8 0.2 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 ORY17862.1 - 4.1e-60 202.8 0.3 1.4e-59 201.0 0.0 2.1 3 0 0 3 3 1 1 KR domain PS-DH PF14765.6 ORY17862.1 - 4.8e-43 147.5 0.0 8.2e-43 146.7 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 ORY17862.1 - 4.7e-41 141.3 0.1 2.2e-40 139.1 0.1 2.0 1 1 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 ORY17862.1 - 2.9e-34 117.6 0.7 7.8e-34 116.2 0.7 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 ORY17862.1 - 4.5e-19 69.0 0.0 4.4e-18 65.8 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 ORY17862.1 - 9e-13 48.7 0.0 3.1e-12 46.9 0.0 2.0 1 1 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N_2 PF13602.6 ORY17862.1 - 2.4e-12 48.1 0.0 5.5e-11 43.6 0.0 3.1 3 0 0 3 3 3 1 Zinc-binding dehydrogenase Methyltransf_11 PF08241.12 ORY17862.1 - 8e-12 45.7 0.0 2.7e-11 44.0 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.26 ORY17862.1 - 9.7e-12 45.0 0.0 5.6e-11 42.5 0.0 2.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_25 PF13649.6 ORY17862.1 - 1.9e-11 44.5 0.0 1.7e-10 41.4 0.0 2.8 3 0 0 3 3 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY17862.1 - 9.6e-11 41.7 0.0 2.4e-10 40.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY17862.1 - 6.6e-09 35.8 0.0 1.7e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 ORY17862.1 - 2.1e-07 30.6 0.0 6.1e-07 29.1 0.0 1.8 1 0 0 1 1 1 1 short chain dehydrogenase Ubie_methyltran PF01209.18 ORY17862.1 - 7e-07 28.8 0.0 4.4e-06 26.2 0.0 2.0 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family ADH_N PF08240.12 ORY17862.1 - 0.00023 21.0 0.4 0.00052 19.9 0.4 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.25 ORY17862.1 - 0.00033 21.0 0.0 0.00094 19.5 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.23 ORY17862.1 - 0.0011 18.3 1.1 0.0011 18.3 1.1 1.7 2 0 0 2 2 2 1 Thiolase, N-terminal domain Methyltransf_33 PF10017.9 ORY17862.1 - 0.007 15.5 0.0 0.019 14.1 0.0 1.6 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent YjeF_N PF03853.15 ORY17862.1 - 0.0084 16.0 0.0 0.43 10.4 0.0 2.5 2 0 0 2 2 2 1 YjeF-related protein N-terminus NodS PF05401.11 ORY17862.1 - 0.13 11.9 0.0 0.33 10.6 0.0 1.7 1 0 0 1 1 1 0 Nodulation protein S (NodS) RrnaAD PF00398.20 ORY17862.1 - 0.16 11.0 0.0 0.41 9.7 0.0 1.6 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase FSH1 PF03959.13 ORY17863.1 - 6.4e-28 97.9 0.0 7.9e-28 97.6 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) FAD_binding_3 PF01494.19 ORY17864.1 - 2.2e-06 27.1 0.2 0.36 10.0 0.0 3.1 3 0 0 3 3 3 3 FAD binding domain YtpI PF14007.6 ORY17865.1 - 0.0043 17.2 1.0 0.74 10.0 1.0 2.2 1 1 0 1 1 1 1 YtpI-like protein DUF3302 PF11742.8 ORY17865.1 - 0.07 13.3 0.2 0.07 13.3 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3302) MFS_1 PF07690.16 ORY17866.1 - 5.8e-30 104.4 35.0 5.8e-30 104.4 35.0 2.6 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF3325 PF11804.8 ORY17866.1 - 0.079 13.1 0.3 0.079 13.1 0.3 3.8 5 0 0 5 5 5 0 Protein of unknown function (DUF3325) Spore_III_AF PF09581.10 ORY17866.1 - 0.13 12.2 0.3 0.22 11.5 0.3 1.3 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) NACHT PF05729.12 ORY17867.1 - 2e-08 34.4 0.2 0.00017 21.5 0.0 2.6 2 0 0 2 2 2 2 NACHT domain Ank PF00023.30 ORY17867.1 - 1.2e-07 31.8 0.1 6.4 7.4 0.0 5.1 3 1 1 4 4 4 2 Ankyrin repeat Helo_like_N PF17111.5 ORY17867.1 - 4.5e-05 22.9 0.1 0.0001 21.8 0.1 1.5 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins AAA_16 PF13191.6 ORY17867.1 - 0.00011 22.6 0.2 0.0013 19.1 0.0 2.8 2 1 0 2 2 2 1 AAA ATPase domain Ank_4 PF13637.6 ORY17867.1 - 0.0034 17.9 0.0 10 6.9 0.0 4.7 5 0 0 5 5 5 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 ORY17867.1 - 0.0053 17.3 0.0 0.35 11.5 0.0 3.5 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) ABC_tran PF00005.27 ORY17867.1 - 0.015 15.8 0.1 0.058 13.9 0.0 2.0 2 0 0 2 2 2 0 ABC transporter NB-ARC PF00931.22 ORY17867.1 - 0.025 13.7 0.0 0.84 8.8 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_23 PF13476.6 ORY17867.1 - 0.029 14.9 0.3 0.14 12.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 ORY17867.1 - 0.03 14.1 0.1 0.12 12.2 0.1 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_22 PF13401.6 ORY17867.1 - 0.041 14.2 0.0 0.21 11.9 0.0 2.2 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 ORY17867.1 - 0.076 13.4 0.0 0.17 12.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_30 PF13604.6 ORY17867.1 - 0.11 12.3 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 ORY17867.1 - 0.14 12.3 0.0 0.35 10.9 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase EcKinase PF02958.20 ORY17868.1 - 2.5e-12 46.7 0.0 3.9e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase APH PF01636.23 ORY17868.1 - 5.8e-10 39.5 0.8 1.3e-09 38.4 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family VbhA PF18495.1 ORY17868.1 - 0.096 12.6 0.0 0.27 11.2 0.0 1.7 1 0 0 1 1 1 0 Antitoxin VbhA Pro-kuma_activ PF09286.11 ORY17869.1 - 3.1e-32 111.8 1.4 1.8e-30 106.1 0.2 2.4 2 0 0 2 2 2 2 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 ORY17869.1 - 0.00018 20.9 6.6 0.00018 20.9 6.6 1.8 2 0 0 2 2 2 1 Subtilase family Astacin PF01400.24 ORY17870.1 - 1.7e-11 44.1 3.5 6e-09 35.8 0.6 2.3 1 1 0 2 2 2 2 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.24 ORY17870.1 - 0.0034 17.2 0.3 0.0062 16.4 0.3 1.4 1 0 0 1 1 1 1 Matrixin Reprolysin_3 PF13582.6 ORY17870.1 - 0.0044 17.5 0.9 0.0079 16.7 0.9 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 ORY17870.1 - 0.0051 17.0 0.2 0.008 16.3 0.2 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 ORY17870.1 - 0.0067 16.1 0.5 0.012 15.2 0.3 1.5 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Metallopep PF12044.8 ORY17870.1 - 0.018 13.7 0.1 0.023 13.3 0.1 1.1 1 0 0 1 1 1 0 Putative peptidase family Peptidase_M43 PF05572.13 ORY17870.1 - 0.082 12.8 0.3 0.13 12.1 0.3 1.3 1 0 0 1 1 1 0 Pregnancy-associated plasma protein-A Reprolysin_2 PF13574.6 ORY17870.1 - 0.22 11.4 0.4 0.41 10.5 0.4 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like DUF4953 PF16313.5 ORY17870.1 - 0.83 8.8 3.5 1.3 8.2 3.5 1.2 1 0 0 1 1 1 0 Met-zincin Astacin PF01400.24 ORY17871.1 - 0.031 13.9 0.1 0.05 13.2 0.1 1.2 1 0 0 1 1 1 0 Astacin (Peptidase family M12A) HATPase_c_5 PF14501.6 ORY17871.1 - 0.074 13.0 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 GHKL domain Astacin PF01400.24 ORY17872.1 - 2e-14 53.7 0.1 3.9e-09 36.4 0.1 2.2 2 0 0 2 2 2 2 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.24 ORY17872.1 - 0.011 15.6 0.0 0.018 14.9 0.0 1.5 1 0 0 1 1 1 0 Matrixin Reprolysin_4 PF13583.6 ORY17872.1 - 0.018 14.7 0.1 0.037 13.7 0.1 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 ORY17872.1 - 0.019 15.1 1.5 0.022 14.9 0.1 1.8 2 0 0 2 2 2 0 Metallo-peptidase family M12 DUF45 PF01863.17 ORY17872.1 - 0.16 12.0 0.4 0.26 11.3 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF45 Reprolysin_3 PF13582.6 ORY17872.1 - 0.16 12.5 0.2 0.5 10.9 0.1 1.9 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin PF01421.19 ORY17872.1 - 0.17 11.8 0.0 0.74 9.7 0.0 1.9 2 0 0 2 2 2 0 Reprolysin (M12B) family zinc metalloprotease CHAT PF12770.7 ORY17875.1 - 2e-15 57.0 0.1 4.9e-15 55.7 0.1 1.6 1 0 0 1 1 1 1 CHAT domain NACHT PF05729.12 ORY17875.1 - 0.0072 16.3 0.1 0.22 11.4 0.0 2.6 3 0 0 3 3 3 1 NACHT domain AAA_22 PF13401.6 ORY17875.1 - 0.051 13.9 0.0 0.14 12.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 ORY17875.1 - 0.097 13.1 0.0 0.32 11.4 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 ORY17875.1 - 0.15 12.4 0.1 0.6 10.5 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain XPC-binding PF09280.11 ORY17905.1 - 1.9e-24 85.1 10.2 3e-24 84.5 10.2 1.3 1 0 0 1 1 1 1 XPC-binding domain ubiquitin PF00240.23 ORY17905.1 - 1.6e-21 75.8 0.1 2.5e-21 75.2 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 ORY17905.1 - 5e-09 35.9 0.9 1.3e-08 34.5 0.9 1.8 1 0 0 1 1 1 1 UBA/TS-N domain Rad60-SLD PF11976.8 ORY17905.1 - 1.7e-07 30.9 0.3 2.5e-07 30.4 0.3 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 ORY17905.1 - 0.026 14.6 0.0 0.049 13.7 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 ORY17905.1 - 0.11 13.0 0.0 0.2 12.1 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-like domain CCDC53 PF10152.9 ORY17905.1 - 1.1 9.6 3.3 1.5 9.2 1.2 2.1 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex MMR_HSR1 PF01926.23 ORY17907.1 - 6.1e-06 26.3 0.0 6.1e-06 26.3 0.0 2.2 3 0 0 3 3 3 1 50S ribosome-binding GTPase Baculo_PEP_C PF04513.12 ORY17907.1 - 0.5 10.4 9.6 2.5 8.1 4.0 2.6 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Dynamin_N PF00350.23 ORY17907.1 - 1.2 9.2 0.0 1.2 9.2 0.0 3.5 2 2 1 3 3 3 0 Dynamin family Fungal_TACC PF12709.7 ORY17907.1 - 1.3 9.5 23.3 0.32 11.5 0.7 3.7 3 0 0 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins PEX11 PF05648.14 ORY17907.1 - 1.4 8.4 6.2 0.26 10.7 0.3 2.3 2 0 0 2 2 2 0 Peroxisomal biogenesis factor 11 (PEX11) Prominin PF05478.11 ORY17907.1 - 3.7 5.4 13.5 5.6 4.8 13.5 1.2 1 0 0 1 1 1 0 Prominin YlqD PF11068.8 ORY17907.1 - 6 7.3 34.3 0.74 10.2 12.2 2.5 1 1 1 2 2 2 0 YlqD protein Viral_P18 PF04521.13 ORY17907.1 - 9.1 6.1 11.9 0.41 10.4 1.9 3.3 2 1 2 4 4 4 0 ssRNA positive strand viral 18kD cysteine rich protein ERM PF00769.19 ORY17908.1 - 4.7e-06 26.6 1.4 5.2e-06 26.5 1.4 1.2 1 0 0 1 1 1 1 Ezrin/radixin/moesin family DUF2968 PF11180.8 ORY17908.1 - 0.012 15.2 9.5 0.026 14.2 9.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) Phage_int_SAM_1 PF02899.17 ORY17908.1 - 0.13 12.6 2.2 0.19 12.1 0.9 1.9 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain RPA_interact_M PF14767.6 ORY17908.1 - 1.4 9.5 5.9 5.1 7.7 5.8 2.1 1 1 0 1 1 1 0 Replication protein A interacting middle CSN5_C PF18323.1 ORY17908.1 - 9.8 7.2 10.7 70 4.4 10.7 2.6 1 1 0 1 1 1 0 Cop9 signalosome subunit 5 C-terminal domain HSP70 PF00012.20 ORY17909.1 - 1.1e-07 30.5 0.0 2.3e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Hsp70 protein BTB PF00651.31 ORY17910.1 - 2.1e-06 27.9 0.0 3.3e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain CDC45 PF02724.14 ORY17910.1 - 0.36 9.1 8.4 0.44 8.8 8.4 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 ORY17910.1 - 1.7 8.0 17.4 2.2 7.7 17.4 1.1 1 0 0 1 1 1 0 SDA1 Glypican PF01153.19 ORY17910.1 - 1.7 7.4 6.9 2.3 7.0 6.9 1.1 1 0 0 1 1 1 0 Glypican TMEM119 PF15724.5 ORY17910.1 - 5 7.1 13.0 6.9 6.7 12.6 1.4 1 1 0 1 1 1 0 TMEM119 family RRP36 PF06102.12 ORY17911.1 - 2.3e-51 174.1 31.2 2.3e-51 174.1 31.2 2.2 2 0 0 2 2 2 1 rRNA biogenesis protein RRP36 NIF PF03031.18 ORY17912.1 - 1.2e-24 86.9 0.1 2.2e-24 86.0 0.0 1.4 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase Glyoxalase PF00903.25 ORY17917.1 - 3.6e-21 75.7 0.3 7.3e-16 58.5 0.0 2.3 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 ORY17917.1 - 1.2e-13 51.3 0.1 2.3e-05 24.6 0.0 2.4 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_5 PF14696.6 ORY17917.1 - 1.2e-06 28.7 0.2 0.00023 21.4 0.2 2.9 2 1 0 2 2 2 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase_3 PF13468.6 ORY17917.1 - 8.7e-06 26.0 0.0 0.29 11.2 0.0 3.1 2 1 0 2 2 2 2 Glyoxalase-like domain DUF4844 PF16133.5 ORY17917.1 - 0.14 12.7 0.0 0.37 11.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4844) Zn_clus PF00172.18 ORY17918.1 - 4.4e-05 23.5 8.1 9.1e-05 22.5 8.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ORY17918.1 - 0.044 12.8 0.4 7.4 5.5 0.1 2.3 2 0 0 2 2 2 0 Fungal specific transcription factor domain TauD PF02668.16 ORY17919.1 - 1.1e-20 74.5 0.1 1.8e-20 73.8 0.1 1.3 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family UNC-93 PF05978.16 ORY17920.1 - 2.8e-09 36.9 5.9 7.1e-09 35.6 5.9 1.6 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 ORY17920.1 - 1.4e-06 27.5 15.7 1.4e-06 27.5 15.7 2.3 1 1 1 2 2 2 1 Major Facilitator Superfamily Peptidase_M48_N PF16491.5 ORY17920.1 - 0.042 13.7 7.9 0.2 11.6 0.8 3.3 3 1 0 3 3 3 0 CAAX prenyl protease N-terminal, five membrane helices Fer2_2 PF01799.20 ORY17920.1 - 0.085 12.9 0.1 4.3 7.4 0.0 2.5 2 0 0 2 2 2 0 [2Fe-2S] binding domain Zip PF02535.22 ORY17922.1 - 7.1e-53 180.0 6.8 4.1e-52 177.5 6.8 1.8 1 1 0 1 1 1 1 ZIP Zinc transporter Cation_efflux PF01545.21 ORY17923.1 - 6.6e-24 84.7 15.4 8.3e-24 84.4 15.4 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 ORY17923.1 - 1.6e-08 34.5 0.2 3.3e-08 33.6 0.2 1.5 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter SbcD_C PF12320.8 ORY17923.1 - 0.18 12.2 0.5 1.4 9.2 0.3 2.3 1 1 1 2 2 2 0 Type 5 capsule protein repressor C-terminal domain ArnB_C PF18677.1 ORY17924.1 - 0.24 11.6 2.8 0.42 10.7 2.8 1.4 1 0 0 1 1 1 0 Archaellum regulatory network B, C-terminal domain DUF4200 PF13863.6 ORY17927.1 - 0.0008 19.8 24.1 0.91 9.9 24.1 2.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4200) Nup88 PF10168.9 ORY17927.1 - 3.2 5.4 12.0 3.7 5.3 12.0 1.1 1 0 0 1 1 1 0 Nuclear pore component DUF4047 PF13256.6 ORY17927.1 - 4.1 7.6 8.1 0.64 10.2 0.4 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF4047) DUF641 PF04859.12 ORY17929.1 - 0.093 13.1 0.3 0.17 12.2 0.3 1.4 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) Tetradecapep PF08187.11 ORY17930.1 - 0.25 11.4 0.6 0.54 10.4 0.3 1.6 1 1 0 1 1 1 0 Myoactive tetradecapeptides family ADH_zinc_N PF00107.26 ORY17931.1 - 5.9e-09 36.0 0.0 1e-08 35.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_2 PF03446.15 ORY17931.1 - 0.0016 18.6 0.1 0.0025 18.0 0.1 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 ORY17931.1 - 0.0044 16.4 0.0 0.0066 15.8 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 ORY17931.1 - 0.098 11.9 0.1 0.14 11.5 0.1 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain AMP-binding PF00501.28 ORY17932.1 - 3.8e-16 58.7 0.0 4.4e-16 58.5 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme Cdd1 PF11731.8 ORY17932.1 - 0.0046 17.2 0.0 0.013 15.7 0.0 1.8 2 0 0 2 2 2 1 Pathogenicity locus NAD_binding_4 PF07993.12 ORY17933.1 - 0.00076 18.7 0.0 0.0011 18.2 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Glyco_transf_90 PF05686.12 ORY17935.1 - 2.8e-19 69.3 0.2 6.6e-16 58.2 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 90 adh_short PF00106.25 ORY17936.1 - 2e-16 60.0 0.0 6.5e-15 55.1 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY17936.1 - 4.3e-12 46.1 0.0 3.4e-10 39.9 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY17936.1 - 6.2e-08 32.7 0.0 9.7e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 KR domain PhoLip_ATPase_C PF16212.5 ORY17937.1 - 2.2e-53 181.5 5.0 2.2e-53 181.5 5.0 2.0 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 ORY17937.1 - 5.1e-17 61.3 0.3 1.1e-16 60.2 0.3 1.6 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 ORY17937.1 - 6.2e-13 49.5 1.8 6.9e-07 29.8 1.3 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 ORY17937.1 - 1.5e-08 34.4 0.9 0.00033 20.2 0.0 2.8 3 0 0 3 3 3 2 E1-E2 ATPase Cation_ATPase PF13246.6 ORY17937.1 - 4.1e-07 30.0 0.0 7.8e-06 25.9 0.0 2.4 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 ORY17937.1 - 0.0045 16.8 0.0 0.01 15.6 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Sec16_C PF12931.7 ORY17938.1 - 1.4e-117 392.7 0.0 1.9e-117 392.2 0.0 1.2 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.7 ORY17938.1 - 9.2e-34 116.6 0.0 3.3e-33 114.8 0.0 2.1 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region Tannase PF07519.11 ORY17939.1 - 5.6e-86 289.3 0.0 6.6e-86 289.1 0.0 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_1 PF00561.20 ORY17939.1 - 7e-05 22.6 0.3 0.033 13.8 0.1 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold RPE65 PF03055.15 ORY17940.1 - 1.5e-102 344.2 0.0 1.7e-102 344.0 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Amidohydro_2 PF04909.14 ORY17941.1 - 9.5e-32 110.9 0.1 1.2e-31 110.6 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase Cas9_b_hairpin PF17893.1 ORY17941.1 - 0.12 12.2 0.0 0.31 10.9 0.0 1.6 2 0 0 2 2 2 0 CRISPR-associated endonuclease Cas9 beta-hairpin domain SnoaL_4 PF13577.6 ORY17942.1 - 6e-30 104.0 0.1 8e-30 103.6 0.1 1.2 1 0 0 1 1 1 1 SnoaL-like domain PAH PF02671.21 ORY17942.1 - 0.0041 17.2 0.2 0.0085 16.2 0.2 1.6 1 1 0 1 1 1 1 Paired amphipathic helix repeat Aldedh PF00171.22 ORY17943.1 - 2.3e-154 514.4 0.1 2.7e-154 514.1 0.1 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Fungal_trans PF04082.18 ORY17943.1 - 1.4e-18 66.9 1.9 2.6e-18 66.0 1.9 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain LuxC PF05893.14 ORY17943.1 - 0.00068 18.8 0.0 0.0013 17.9 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.11 ORY17943.1 - 0.018 14.5 0.0 0.092 12.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) Erf4 PF10256.9 ORY17944.1 - 0.0054 16.8 0.0 0.0099 16.0 0.0 1.4 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family DUF4646 PF15496.6 ORY17944.1 - 0.052 14.2 0.0 0.075 13.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4646) PP2C_C PF07830.13 ORY17944.1 - 0.16 12.4 6.2 6.2 7.4 2.7 2.4 1 1 1 2 2 2 0 Protein serine/threonine phosphatase 2C, C-terminal domain YkuI_C PF10388.9 ORY17944.1 - 0.48 10.2 3.7 0.79 9.5 3.7 1.2 1 0 0 1 1 1 0 EAL-domain associated signalling protein domain AAA_11 PF13086.6 ORY17944.1 - 1.1 9.0 8.2 1.6 8.5 8.2 1.2 1 0 0 1 1 1 0 AAA domain HSP70 PF00012.20 ORY17944.1 - 2.1 6.4 7.6 2.9 5.9 7.6 1.1 1 0 0 1 1 1 0 Hsp70 protein OmpH PF03938.14 ORY17944.1 - 3.5 8.0 13.7 6 7.2 13.7 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) TMPIT PF07851.13 ORY17944.1 - 7.4 5.7 5.2 10 5.3 5.2 1.2 1 0 0 1 1 1 0 TMPIT-like protein MFS_1 PF07690.16 ORY17945.1 - 4.8e-25 88.2 27.7 4.8e-25 88.2 27.7 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY17945.1 - 1.5e-06 27.3 32.9 1.5e-06 27.3 32.9 3.0 1 1 1 2 2 2 1 Sugar (and other) transporter DUF5090 PF17009.5 ORY17945.1 - 8.5 6.3 15.1 1.3 9.0 6.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF5090) Fungal_trans PF04082.18 ORY17946.1 - 1.6e-26 92.9 0.0 3e-26 92.1 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY17946.1 - 2e-09 37.4 10.9 3.2e-09 36.8 10.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4734 PF15881.5 ORY17948.1 - 3.8 7.7 7.1 2.9 8.1 3.3 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4734) DUF3328 PF11807.8 ORY17949.1 - 1e-48 166.1 0.6 1.3e-48 165.7 0.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Sen15 PF09631.10 ORY17950.1 - 2.9e-23 82.1 0.0 4.6e-23 81.4 0.0 1.3 1 0 0 1 1 1 1 Sen15 protein Fibritin_C PF07921.12 ORY17951.1 - 0.12 12.5 0.3 0.2 11.8 0.3 1.3 1 0 0 1 1 1 0 Fibritin C-terminal region ATF7IP_BD PF16788.5 ORY17951.1 - 1.8 8.6 4.1 2.2 8.4 4.1 1.3 1 0 0 1 1 1 0 ATF-interacting protein binding domain DUF2985 PF11204.8 ORY17952.1 - 3.8e-38 129.5 3.3 3.8e-38 129.5 3.3 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2985) Bacteriocin_IIc PF10439.9 ORY17953.1 - 0.035 14.2 0.7 0.056 13.6 0.7 1.2 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide TFIIA PF03153.13 ORY17953.1 - 0.047 13.7 4.2 0.055 13.5 4.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Apt1 PF10351.9 ORY17953.1 - 0.074 11.9 2.9 0.085 11.7 2.9 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 ORY17953.1 - 0.3 9.6 0.8 0.33 9.4 0.8 1.0 1 0 0 1 1 1 0 Macoilin family Gly-zipper_YMGG PF13441.6 ORY17953.1 - 6.7 6.5 8.5 21 5.0 8.5 1.7 1 1 1 2 2 2 0 YMGG-like Gly-zipper MFS_1 PF07690.16 ORY17954.1 - 2.2e-17 63.0 50.0 2.2e-17 63.0 50.0 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 ORY17954.1 - 1.4e-08 34.5 20.5 2.3e-08 33.8 20.5 1.3 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB AA_permease PF00324.21 ORY17957.1 - 1.1e-65 222.1 29.0 2.1e-65 221.2 29.0 1.4 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ORY17957.1 - 6.3e-25 87.9 24.8 8.6e-25 87.4 24.8 1.2 1 0 0 1 1 1 1 Amino acid permease Med26 PF08711.11 ORY17958.1 - 8.1e-10 38.6 0.0 1.8e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain VSG_B PF13206.6 ORY17958.1 - 1.3 8.3 8.3 1.8 7.7 8.3 1.1 1 0 0 1 1 1 0 Trypanosomal VSG domain CFIA_Pcf11 PF11526.8 ORY17959.1 - 0.00049 20.5 2.8 0.018 15.6 2.8 2.6 1 1 0 1 1 1 1 Subunit of cleavage factor IA Pcf11 CTD_bind PF04818.13 ORY17959.1 - 0.001 19.9 0.0 0.0031 18.3 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase II-binding domain. VHS PF00790.19 ORY17959.1 - 0.061 13.2 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 VHS domain Prok-RING_1 PF14446.6 ORY17959.1 - 0.28 11.1 2.8 0.83 9.6 0.6 2.3 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 zf-C2HC_2 PF13913.6 ORY17959.1 - 1 9.4 5.5 14 5.7 0.6 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf_UBZ PF18439.1 ORY17959.1 - 1.2 8.8 6.9 1.1 8.9 2.0 2.8 2 1 0 2 2 2 0 Ubiquitin-Binding Zinc Finger ADK PF00406.22 ORY17960.1 - 3.1e-60 202.7 0.0 4e-60 202.3 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 ORY17960.1 - 1.2e-22 80.8 0.3 2.1e-22 80.0 0.0 1.5 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.14 ORY17960.1 - 2.7e-17 62.5 0.0 5.7e-17 61.4 0.0 1.6 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.6 ORY17960.1 - 0.00021 21.8 0.0 0.0004 20.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 ORY17960.1 - 0.00062 19.9 0.0 0.0015 18.7 0.0 1.6 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 ORY17960.1 - 0.11 11.8 0.0 0.2 10.9 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin Pectate_lyase_3 PF12708.7 ORY17961.1 - 1.6e-101 338.6 16.4 1.6e-88 296.1 6.4 3.3 2 1 0 2 2 2 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 ORY17961.1 - 2e-06 27.4 0.3 0.087 12.5 0.1 2.7 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase RhoGAP PF00620.27 ORY17962.1 - 1.1e-13 51.3 0.0 1.6e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain Tom5 PF10642.9 ORY17963.1 - 7.2e-19 67.6 0.3 7.8e-19 67.4 0.3 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit or translocase Nup54 PF13874.6 ORY17964.1 - 2.7e-34 118.3 2.1 2.7e-34 118.3 2.1 3.8 3 1 1 4 4 4 1 Nucleoporin complex subunit 54 Nup54_57_C PF18570.1 ORY17964.1 - 4e-05 23.1 6.2 4e-05 23.1 6.2 2.2 2 0 0 2 2 2 1 NUP57/Nup54 C-terminal domain Nucleoporin_FG PF13634.6 ORY17964.1 - 0.00016 22.4 40.8 0.12 13.2 25.8 3.0 1 1 2 3 3 3 2 Nucleoporin FG repeat region CHCH PF06747.13 ORY17965.1 - 2.8e-06 27.3 2.7 2.8e-06 27.3 2.7 2.6 3 0 0 3 3 3 2 CHCH domain CX9C PF16860.5 ORY17965.1 - 0.0036 17.3 7.2 0.011 15.7 2.2 2.3 2 0 0 2 2 2 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Pet191_N PF10203.9 ORY17965.1 - 0.083 13.2 7.7 1.2 9.5 1.0 3.0 2 1 0 3 3 3 0 Cytochrome c oxidase assembly protein PET191 COX6B PF02297.17 ORY17965.1 - 1.3 9.3 9.4 4.7 7.5 0.8 2.2 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb UCR_hinge PF02320.16 ORY17965.1 - 1.6 9.0 10.9 2.7 8.3 6.0 2.9 1 1 1 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein Cmc1 PF08583.10 ORY17965.1 - 2.4 8.2 12.8 1.7 8.7 3.0 2.2 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like CLPTM1 PF05602.12 ORY17966.1 - 8.7e-161 535.7 0.4 1.2e-160 535.3 0.4 1.2 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) Flg_new PF09479.10 ORY17966.1 - 0.033 14.4 0.0 0.14 12.3 0.0 2.2 2 0 0 2 2 2 0 Listeria-Bacteroides repeat domain (List_Bact_rpt) DUF1772 PF08592.11 ORY17966.1 - 2.1 8.7 6.9 1.7 9.0 2.0 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF1772) 2TM PF13239.6 ORY17966.1 - 3.1 8.2 8.8 1.3 9.4 3.0 3.0 2 1 0 2 2 2 0 2TM domain Lysine_decarbox PF03641.14 ORY17967.1 - 5.6e-30 104.1 0.0 8.1e-30 103.6 0.0 1.2 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 ORY17967.1 - 8.6e-05 22.2 1.3 0.00029 20.5 1.3 1.8 1 1 0 1 1 1 1 SLOG cluster4 family LSDAT_prok PF18171.1 ORY17967.1 - 0.021 14.1 0.5 0.029 13.6 0.2 1.5 1 1 0 1 1 1 0 SLOG in TRPM, prokaryote CTD_bind PF04818.13 ORY17968.1 - 3.8e-09 37.3 0.0 8e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase II-binding domain. RRM_1 PF00076.22 ORY17968.1 - 3.2e-07 30.1 0.2 7.7e-07 28.8 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Citrate_synt PF00285.21 ORY17969.1 - 4.7e-103 345.0 0.0 5.9e-103 344.7 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Eclosion PF04736.12 ORY17969.1 - 0.067 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Eclosion hormone Mito_carr PF00153.27 ORY17970.1 - 5.4e-27 93.5 4.1 5.1e-11 42.3 0.0 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein CRT10 PF08728.10 ORY17971.1 - 7.2e-12 44.3 0.0 7.6e-07 27.7 0.0 3.0 3 0 0 3 3 3 3 CRT10 WD40 PF00400.32 ORY17971.1 - 0.57 11.2 1.8 11 7.1 0.0 3.2 2 0 0 2 2 2 0 WD domain, G-beta repeat CENP-I PF07778.11 ORY17972.1 - 1e-46 159.8 0.0 1e-45 156.5 0.0 1.9 1 1 0 1 1 1 1 Mis6 DUF1460 PF07313.12 ORY17973.1 - 0.073 12.4 0.0 0.76 9.1 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1460) SPT_ssu-like PF11779.8 ORY17974.1 - 1.3e-24 85.5 4.7 1.3e-24 85.5 4.7 1.7 2 0 0 2 2 2 1 Small subunit of serine palmitoyltransferase-like RF-1 PF00472.20 ORY17975.1 - 1.2e-27 96.1 3.8 2e-27 95.4 3.8 1.3 1 0 0 1 1 1 1 RF-1 domain DUF3545 PF12065.8 ORY17975.1 - 0.13 12.3 4.7 0.13 12.3 1.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3545) DUF3426 PF11906.8 ORY17975.1 - 0.16 12.1 0.1 0.44 10.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3426) NPR1_interact PF15699.5 ORY17976.1 - 0.1 13.2 0.0 0.16 12.6 0.0 1.2 1 0 0 1 1 1 0 NPR1 interacting MFS_1 PF07690.16 ORY17977.1 - 2.1e-06 26.9 1.4 2.1e-06 26.9 1.4 2.2 1 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY17977.1 - 0.011 14.6 0.0 0.011 14.6 0.0 1.4 2 0 0 2 2 2 0 Sugar (and other) transporter Thioredox_DsbH PF03190.15 ORY17979.1 - 2.2e-65 219.6 0.0 1.1e-61 207.5 0.0 2.3 1 1 0 1 1 1 1 Protein of unknown function, DUF255 Glyco_hydro_9 PF00759.19 ORY17979.1 - 0.00087 18.8 0.5 0.0015 18.1 0.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 Thioredoxin_7 PF13899.6 ORY17979.1 - 0.017 15.3 0.0 2.4 8.4 0.0 2.5 2 0 0 2 2 2 0 Thioredoxin-like C5-epim_C PF06662.13 ORY17979.1 - 0.019 14.5 1.3 0.14 11.7 0.0 2.7 3 0 0 3 3 3 0 D-glucuronyl C5-epimerase C-terminus Glyco_hydro_88 PF07470.13 ORY17979.1 - 0.029 13.5 0.1 1.7 7.7 0.0 2.3 2 0 0 2 2 2 0 Glycosyl Hydrolase Family 88 Glyco_hydro_76 PF03663.14 ORY17979.1 - 2.7 7.4 4.4 3.1 7.2 2.0 2.1 2 1 1 3 3 3 0 Glycosyl hydrolase family 76 CAP PF00188.26 ORY17980.1 - 2.6e-20 73.5 2.3 3.8e-20 73.0 2.3 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family VTC PF09359.10 ORY17982.1 - 1.5e-88 296.8 0.2 1.5e-88 296.8 0.2 1.7 2 0 0 2 2 2 1 VTC domain DUF202 PF02656.15 ORY17982.1 - 8.9e-13 48.5 3.5 1.6e-12 47.6 3.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF202) SPX PF03105.19 ORY17982.1 - 1.2e-06 28.7 15.5 0.003 17.5 0.0 3.5 2 1 1 4 4 4 2 SPX domain KxDL PF10241.9 ORY17982.1 - 0.0032 17.7 1.1 0.17 12.2 0.1 2.6 2 0 0 2 2 2 1 Uncharacterized conserved protein ChitinaseA_N PF08329.10 ORY17982.1 - 0.13 11.9 0.0 0.33 10.6 0.0 1.7 1 0 0 1 1 1 0 Chitinase A, N-terminal domain Prominin PF05478.11 ORY17982.1 - 0.29 9.0 0.0 0.59 8.0 0.0 1.4 1 0 0 1 1 1 0 Prominin Cortex-I_coil PF09304.10 ORY17982.1 - 1.9 8.7 5.1 1 9.6 0.3 2.7 3 0 0 3 3 3 0 Cortexillin I, coiled coil Peptidase_S41 PF03572.18 ORY17983.1 - 4.6e-09 36.0 0.0 1e-08 35.0 0.0 1.5 1 1 0 1 1 1 1 Peptidase family S41 VWA_3 PF13768.6 ORY17983.1 - 0.19 11.7 0.0 0.36 10.8 0.0 1.4 1 0 0 1 1 1 0 von Willebrand factor type A domain FAD_binding_4 PF01565.23 ORY17984.1 - 1.8e-27 95.7 6.6 4.1e-27 94.6 6.6 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 ORY17984.1 - 2.7e-08 33.8 0.0 5.1e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like Chitin_bind_1 PF00187.19 ORY17984.1 - 2.9e-06 27.6 19.9 7e-06 26.4 19.9 1.6 1 0 0 1 1 1 1 Chitin recognition protein Glyco_hydro_61 PF03443.14 ORY17986.1 - 1.3e-68 231.0 0.4 1.7e-68 230.6 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 NPCBM_assoc PF10633.9 ORY17986.1 - 0.046 14.0 1.3 1.1 9.6 0.0 2.7 3 0 0 3 3 3 0 NPCBM-associated, NEW3 domain of alpha-galactosidase FMN_dh PF01070.18 ORY17987.1 - 1e-105 353.6 0.0 1.2e-105 353.4 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 ORY17987.1 - 7.5e-19 67.7 0.0 1.6e-18 66.6 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 ORY17987.1 - 6.3e-07 28.9 0.1 9.5e-07 28.3 0.1 1.1 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 ORY17987.1 - 1.2e-06 27.8 0.1 0.00025 20.1 0.0 2.2 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.21 ORY17987.1 - 0.0068 15.9 0.0 0.024 14.1 0.0 1.8 2 0 0 2 2 2 1 Histidine biosynthesis protein NMO PF03060.15 ORY17987.1 - 0.013 14.9 0.2 0.024 14.0 0.2 1.4 1 0 0 1 1 1 0 Nitronate monooxygenase Tugs PF17840.1 ORY17987.1 - 0.22 11.8 0.5 11 6.3 0.1 2.5 2 0 0 2 2 2 0 Tethering Ubl4a to BAGS domain DUF3402 PF11882.8 ORY17988.1 - 1.2e-191 637.8 0.0 1.5e-191 637.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3402) N1221 PF07923.13 ORY17988.1 - 6.6e-84 281.5 0.0 1e-83 280.9 0.0 1.3 1 0 0 1 1 1 1 N1221-like protein HLH PF00010.26 ORY17989.1 - 9.2e-13 47.9 0.5 1.6e-12 47.1 0.5 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Pox_A30L_A26L PF06086.12 ORY17989.1 - 0.04 13.6 0.0 0.063 13.0 0.0 1.2 1 0 0 1 1 1 0 Orthopoxvirus A26L/A30L protein DUF5333 PF17267.2 ORY17989.1 - 0.044 14.0 0.5 0.12 12.6 0.4 1.8 1 1 0 1 1 1 0 Family of unknown function (DUF5333) CobN-Mg_chel PF02514.16 ORY17990.1 - 0.13 10.0 4.5 0.18 9.5 4.5 1.1 1 0 0 1 1 1 0 CobN/Magnesium Chelatase Spc7 PF08317.11 ORY17990.1 - 0.6 8.9 13.8 1 8.1 13.8 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein FlxA PF14282.6 ORY17990.1 - 2.2 8.3 24.9 0.73 9.8 13.6 2.9 3 0 0 3 3 3 0 FlxA-like protein Hira PF07569.11 ORY17990.1 - 9.5 5.9 10.3 6.1 6.5 8.4 1.4 1 1 0 1 1 1 0 TUP1-like enhancer of split JmjC PF02373.22 ORY17991.1 - 2.1e-38 131.3 0.7 4.4e-38 130.2 0.7 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase zf-HC5HC2H_2 PF13832.6 ORY17991.1 - 5.2e-17 62.0 0.5 9.5e-17 61.2 0.5 1.4 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 ORY17991.1 - 2.6e-16 59.7 1.1 5e-16 58.7 1.1 1.5 1 0 0 1 1 1 1 PHD-like zinc-binding domain JmjN PF02375.17 ORY17991.1 - 3.4e-14 52.5 1.3 3.4e-14 52.5 1.3 2.3 2 0 0 2 2 2 1 jmjN domain zf-C2H2_8 PF15909.5 ORY17991.1 - 0.049 13.9 0.1 0.13 12.6 0.1 1.6 1 0 0 1 1 1 0 C2H2-type zinc ribbon PHD PF00628.29 ORY17991.1 - 0.48 10.3 3.0 1.1 9.1 3.0 1.6 1 0 0 1 1 1 0 PHD-finger PUF PF00806.19 ORY17992.1 - 1.6e-61 200.6 10.6 2.9e-08 33.0 0.2 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat Nup54_57_C PF18570.1 ORY17992.1 - 0.12 12.0 0.4 0.32 10.6 0.4 1.7 1 0 0 1 1 1 0 NUP57/Nup54 C-terminal domain CCB1 PF12046.8 ORY17995.1 - 0.057 12.8 0.0 0.079 12.3 0.0 1.2 1 0 0 1 1 1 0 Cofactor assembly of complex C subunit B ECSCR PF15820.5 ORY17995.1 - 0.1 12.4 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator DUF2627 PF11118.8 ORY17995.1 - 0.11 13.0 0.0 0.21 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2627) Phosphodiest PF01663.22 ORY17996.1 - 3.1e-13 50.0 0.1 5.2e-13 49.3 0.1 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 ORY17996.1 - 0.00018 20.9 0.2 0.00033 20.1 0.2 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 ORY17996.1 - 0.0023 17.4 0.1 0.0039 16.6 0.1 1.4 1 0 0 1 1 1 1 Sulfatase PglZ PF08665.12 ORY17996.1 - 0.14 12.3 0.8 16 5.6 0.0 2.4 2 0 0 2 2 2 0 PglZ domain Gly-zipper_Omp PF13488.6 ORY17996.1 - 0.73 9.9 8.2 2.2 8.4 8.2 1.8 1 0 0 1 1 1 0 Glycine zipper PRIMA1 PF16101.5 ORY18002.1 - 6.3 6.9 8.3 2.9 8.0 5.8 1.6 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 AAA_2 PF07724.14 ORY18004.1 - 4.4e-39 134.3 0.0 1.2e-38 133.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 ORY18004.1 - 1.8e-14 54.3 0.0 3.6e-14 53.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 ORY18004.1 - 3.1e-09 36.8 0.0 6.9e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 ORY18004.1 - 2e-08 34.3 0.0 4.2e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 ORY18004.1 - 0.00049 19.5 0.5 0.021 14.2 0.1 3.0 2 1 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 ORY18004.1 - 0.0015 19.0 0.1 0.0077 16.6 0.1 2.2 2 1 0 2 2 2 1 AAA ATPase domain Sigma54_activat PF00158.26 ORY18004.1 - 0.0016 18.2 0.0 0.076 12.7 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain RuvB_N PF05496.12 ORY18004.1 - 0.0018 18.0 0.3 0.047 13.4 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain MCM PF00493.23 ORY18004.1 - 0.0028 16.8 0.0 0.0063 15.6 0.0 1.5 1 0 0 1 1 1 1 MCM P-loop domain AAA_22 PF13401.6 ORY18004.1 - 0.0051 17.1 0.1 0.049 13.9 0.1 2.4 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 ORY18004.1 - 0.0089 15.8 0.0 0.022 14.5 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_24 PF13479.6 ORY18004.1 - 0.015 15.0 0.0 0.023 14.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 ORY18004.1 - 0.021 14.3 0.0 0.04 13.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_3 PF07726.11 ORY18004.1 - 0.037 13.9 0.0 0.082 12.8 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 ORY18004.1 - 0.12 12.7 0.0 0.24 11.8 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Sigma54_activ_2 PF14532.6 ORY18004.1 - 0.13 12.4 0.0 0.29 11.2 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain ABC_tran PF00005.27 ORY18004.1 - 0.14 12.7 0.0 0.33 11.5 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_18 PF13238.6 ORY18004.1 - 0.14 12.7 0.4 0.73 10.4 0.0 2.3 3 0 0 3 3 3 0 AAA domain AAA_14 PF13173.6 ORY18004.1 - 0.15 12.1 0.0 0.33 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATP-synt_ab PF00006.25 ORY18005.1 - 7.5e-61 205.5 0.0 2.2e-60 204.0 0.0 1.8 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain Alpha-amylase_C PF02806.18 ORY18005.1 - 2.5e-26 92.0 0.1 6.8e-26 90.6 0.1 1.8 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain ATP-synt_ab_N PF02874.23 ORY18005.1 - 5.6e-22 78.0 0.7 1.6e-21 76.5 0.7 1.9 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain CBM_48 PF02922.18 ORY18005.1 - 6.1e-16 58.6 0.0 1.3e-15 57.5 0.0 1.6 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 ORY18005.1 - 1.7e-13 50.9 0.1 3.1e-10 40.1 0.2 2.4 1 1 1 2 2 2 2 Alpha amylase, catalytic domain RsgA_GTPase PF03193.16 ORY18005.1 - 0.039 13.8 0.2 0.1 12.5 0.2 1.6 1 0 0 1 1 1 0 RsgA GTPase NB-ARC PF00931.22 ORY18005.1 - 0.056 12.6 0.4 0.18 11.0 0.1 1.8 2 0 0 2 2 2 0 NB-ARC domain AAA PF00004.29 ORY18005.1 - 0.12 12.8 0.1 2.5 8.5 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 ORY18005.1 - 0.13 12.2 0.0 0.35 10.8 0.0 1.7 1 0 0 1 1 1 0 NACHT domain T3SS_ATPase_C PF18269.1 ORY18005.1 - 0.14 12.1 0.6 0.42 10.5 0.6 1.8 1 1 0 1 1 1 0 T3SS EscN ATPase C-terminal domain ATPase PF06745.13 ORY18005.1 - 0.21 10.9 0.2 0.39 10.0 0.2 1.4 1 0 0 1 1 1 0 KaiC AAA_19 PF13245.6 ORY18005.1 - 0.93 9.8 4.2 1.5 9.2 0.2 3.0 4 0 0 4 4 4 0 AAA domain Arm PF00514.23 ORY18006.1 - 3.9e-14 52.1 1.0 0.00029 20.8 0.0 7.5 8 0 0 8 8 8 2 Armadillo/beta-catenin-like repeat V-ATPase_H_N PF03224.14 ORY18006.1 - 4e-05 23.1 0.1 0.031 13.6 0.0 3.6 3 1 0 3 3 3 1 V-ATPase subunit H HEAT_EZ PF13513.6 ORY18006.1 - 0.0012 19.3 5.0 3.7 8.2 0.0 6.0 6 0 0 6 6 6 1 HEAT-like repeat HEAT_2 PF13646.6 ORY18006.1 - 0.013 15.9 1.5 0.14 12.6 0.0 3.7 4 0 0 4 4 4 0 HEAT repeats IFRD PF05004.13 ORY18006.1 - 0.029 13.5 0.0 0.11 11.6 0.0 1.9 1 0 0 1 1 1 0 Interferon-related developmental regulator (IFRD) RES PF08808.11 ORY18006.1 - 0.038 13.9 0.1 0.17 11.7 0.0 2.0 2 0 0 2 2 2 0 RES domain Xpo1 PF08389.12 ORY18006.1 - 0.039 14.0 0.5 0.27 11.3 0.1 2.4 2 0 0 2 2 2 0 Exportin 1-like protein MethyTransf_Reg PF10119.9 ORY18006.1 - 0.046 14.4 0.7 0.16 12.7 0.1 2.2 3 0 0 3 3 3 0 Predicted methyltransferase regulatory domain VPS9 PF02204.18 ORY18006.1 - 0.091 13.0 0.0 5.3 7.3 0.0 3.0 3 0 0 3 3 3 0 Vacuolar sorting protein 9 (VPS9) domain Cyclin PF08613.11 ORY18008.1 - 3.1e-29 102.4 0.0 9.1e-29 100.9 0.0 1.7 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 ORY18008.1 - 0.00035 20.3 0.0 0.00053 19.7 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Hist_deacetyl PF00850.19 ORY18010.1 - 1.1e-85 287.9 0.1 1.6e-85 287.3 0.1 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Arb2 PF09757.9 ORY18010.1 - 7.4e-85 284.2 1.4 1e-84 283.7 1.4 1.2 1 0 0 1 1 1 1 Arb2 domain Gp_dh_C PF02800.20 ORY18011.1 - 1.3e-71 239.3 0.1 2e-71 238.7 0.1 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 ORY18011.1 - 3.6e-38 130.0 0.1 8.3e-38 128.8 0.1 1.6 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 ORY18011.1 - 0.026 14.6 0.1 0.11 12.7 0.0 2.1 3 0 0 3 3 3 0 Dihydrodipicolinate reductase, N-terminus COX4 PF02936.14 ORY18013.1 - 1.5e-39 135.1 0.1 2e-39 134.8 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV SNARE_assoc PF09335.11 ORY18013.1 - 0.0054 17.2 0.0 0.0078 16.7 0.0 1.2 1 0 0 1 1 1 1 SNARE associated Golgi protein DUF3106 PF11304.8 ORY18013.1 - 0.021 15.3 3.0 0.021 15.3 3.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3106) TRI12 PF06609.13 ORY18013.1 - 0.025 13.0 0.0 0.032 12.6 0.0 1.1 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) TraE PF05309.11 ORY18013.1 - 0.063 12.6 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 TraE protein DUF1289 PF06945.13 ORY18013.1 - 9.4 6.1 6.2 15 5.5 0.3 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1289) Molybdopterin PF00384.22 ORY18016.1 - 1.3e-73 248.4 0.0 7.3e-72 242.7 0.0 2.2 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Fer2_4 PF13510.6 ORY18016.1 - 5e-20 71.3 0.4 1.6e-19 69.7 0.1 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain NADH_dhqG_C PF09326.11 ORY18016.1 - 2.6e-18 66.4 0.0 6.9e-18 65.1 0.0 1.8 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit G, C-terminal NADH-G_4Fe-4S_3 PF10588.9 ORY18016.1 - 2.8e-17 62.0 0.2 2.8e-17 62.0 0.2 2.0 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2 PF00111.27 ORY18016.1 - 6.7e-08 32.4 0.5 6.7e-08 32.4 0.5 2.0 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.22 ORY18016.1 - 0.004 16.9 0.0 0.15 11.8 0.0 2.4 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain LtrA PF06772.11 ORY18017.1 - 9.7e-43 146.7 24.1 1.3e-42 146.3 24.1 1.2 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) Histone PF00125.24 ORY18017.1 - 0.097 13.0 0.0 0.18 12.2 0.0 1.3 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 Na_H_Exchanger PF00999.21 ORY18018.1 - 2.8e-49 167.9 18.9 3.5e-49 167.6 18.9 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family FA_desaturase PF00487.24 ORY18019.1 - 1.4e-24 87.3 20.1 4.5e-24 85.7 20.1 1.9 1 1 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 ORY18019.1 - 0.001 19.3 0.0 0.0023 18.1 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) TPT PF03151.16 ORY18021.1 - 4.4e-57 193.7 8.9 5.3e-57 193.4 8.9 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 ORY18021.1 - 3.7e-10 39.5 10.9 7.7e-10 38.5 10.9 1.5 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 ORY18021.1 - 6.2e-07 29.7 27.7 0.00012 22.2 12.0 2.9 2 1 0 2 2 2 2 EamA-like transporter family Nuc_sug_transp PF04142.15 ORY18021.1 - 0.094 11.9 1.8 0.14 11.3 0.1 1.9 2 0 0 2 2 2 0 Nucleotide-sugar transporter PSII PF00421.19 ORY18021.1 - 0.1 11.3 0.0 0.16 10.7 0.0 1.2 1 0 0 1 1 1 0 Photosystem II protein RmuC PF02646.16 ORY18021.1 - 0.23 10.6 0.0 0.33 10.0 0.0 1.1 1 0 0 1 1 1 0 RmuC family Phage_holin_5_2 PF16079.5 ORY18021.1 - 1.3 9.4 4.6 1.9 8.9 0.6 2.6 2 0 0 2 2 2 0 Phage holin family Hol44, in holin superfamily V Peptidase_S9 PF00326.21 ORY18022.1 - 3.9e-11 42.8 0.1 6.4e-11 42.1 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 ORY18022.1 - 0.00014 21.7 0.0 0.0027 17.6 0.0 2.2 1 1 1 2 2 2 1 Phospholipase/Carboxylesterase Esterase PF00756.20 ORY18022.1 - 0.026 14.2 0.1 0.16 11.6 0.1 2.1 1 1 0 2 2 2 0 Putative esterase PUF PF00806.19 ORY18023.1 - 1.2e-36 122.4 2.1 1.6e-05 24.3 0.0 8.9 9 0 0 9 9 9 8 Pumilio-family RNA binding repeat SOG2 PF10428.9 ORY18023.1 - 2.3 7.3 11.3 3.6 6.7 11.3 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein RHD3 PF05879.12 ORY18024.1 - 0 1038.4 0.0 0 1038.1 0.0 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.19 ORY18024.1 - 2.6e-08 33.4 0.1 4.7e-08 32.6 0.1 1.3 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.23 ORY18024.1 - 4.5e-05 23.6 0.1 0.00011 22.3 0.0 1.7 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 ORY18024.1 - 0.00014 21.9 0.0 0.00033 20.7 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_28 PF13521.6 ORY18024.1 - 0.027 14.7 0.0 0.13 12.5 0.0 2.2 1 0 0 1 1 1 0 AAA domain IP_trans PF02121.18 ORY18024.1 - 0.052 13.1 0.1 0.099 12.2 0.1 1.4 1 0 0 1 1 1 0 Phosphatidylinositol transfer protein Ras PF00071.22 ORY18026.1 - 1.8e-63 213.0 0.2 2.1e-63 212.7 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY18026.1 - 2.1e-35 121.6 0.2 2.9e-35 121.1 0.2 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY18026.1 - 2.9e-13 49.6 0.1 3.9e-13 49.2 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 ORY18026.1 - 8.1e-08 32.3 0.1 1.3e-07 31.7 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ORY18026.1 - 8.9e-05 22.4 0.1 0.016 15.1 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 ORY18026.1 - 0.00025 20.6 0.1 0.0013 18.4 0.1 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 ORY18026.1 - 0.00037 19.9 0.1 0.0006 19.2 0.1 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.6 ORY18026.1 - 0.0026 18.0 0.0 0.017 15.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain SRPRB PF09439.10 ORY18026.1 - 0.011 15.1 0.0 0.019 14.4 0.0 1.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_14 PF13173.6 ORY18026.1 - 0.012 15.6 0.2 0.038 14.0 0.1 1.9 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 ORY18026.1 - 0.014 15.9 0.6 0.034 14.7 0.6 1.9 1 1 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 ORY18026.1 - 0.018 14.7 0.2 0.041 13.6 0.2 2.0 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 ORY18026.1 - 0.021 15.2 0.1 0.032 14.6 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain TniB PF05621.11 ORY18026.1 - 0.038 13.4 0.0 0.17 11.3 0.0 1.9 2 0 0 2 2 2 0 Bacterial TniB protein SpoIIID PF12116.8 ORY18026.1 - 0.066 13.3 0.1 1.6 8.8 0.0 2.4 2 0 0 2 2 2 0 Stage III sporulation protein D FeoB_N PF02421.18 ORY18026.1 - 0.098 12.2 0.1 0.25 10.8 0.0 1.6 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_7 PF12775.7 ORY18026.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_21 PF13304.6 ORY18026.1 - 0.12 12.1 0.6 0.18 11.6 0.5 1.4 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_5 PF07728.14 ORY18026.1 - 0.14 12.2 0.0 0.31 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) zf_CCCH_4 PF18345.1 ORY18027.1 - 5.7e-09 35.7 38.2 3.4e-06 26.9 5.6 4.4 4 1 0 4 4 4 3 Zinc finger domain zf-CCCH PF00642.24 ORY18027.1 - 8.7e-09 35.1 22.5 0.00031 20.6 5.0 3.8 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Chromo PF00385.24 ORY18027.1 - 3.7e-07 29.9 0.2 8.5e-07 28.8 0.2 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Torus PF16131.5 ORY18027.1 - 1.2e-05 26.0 18.9 0.0037 17.9 0.5 5.1 5 1 1 6 6 6 3 Torus domain zf-CCCH_4 PF18044.1 ORY18027.1 - 0.00044 20.0 35.7 0.0073 16.1 4.4 4.3 4 0 0 4 4 4 3 CCCH-type zinc finger zf-CCCH_3 PF15663.5 ORY18027.1 - 0.0011 19.2 15.3 0.2 11.9 0.8 4.0 3 1 0 3 3 3 2 Zinc-finger containing family WD40 PF00400.32 ORY18028.1 - 1.3e-09 38.5 8.6 0.02 15.8 0.0 5.8 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY18028.1 - 0.0091 16.3 0.0 25 5.2 0.0 4.4 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Myb_DNA-bind_6 PF13921.6 ORY18028.1 - 0.051 13.8 0.4 0.51 10.6 0.2 2.7 2 1 1 3 3 3 0 Myb-like DNA-binding domain TF_Zn_Ribbon PF08271.12 ORY18028.1 - 0.91 9.1 7.0 0.3 10.7 0.2 2.7 2 0 0 2 2 2 0 TFIIB zinc-binding Shugoshin_C PF07557.11 ORY18028.1 - 4.6 7.1 5.8 0.39 10.6 0.2 2.2 2 0 0 2 2 2 0 Shugoshin C terminus DZR PF12773.7 ORY18028.1 - 5.9 7.0 6.9 2.8e+02 1.6 7.3 2.6 1 1 0 1 1 1 0 Double zinc ribbon AA_permease_2 PF13520.6 ORY18029.1 - 1.1e-67 228.8 53.0 1.3e-67 228.5 53.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ORY18029.1 - 2e-33 115.7 47.9 2.7e-33 115.3 47.9 1.0 1 0 0 1 1 1 1 Amino acid permease Phage_holin_4_1 PF05105.12 ORY18029.1 - 7.8 6.7 14.8 0.16 12.1 3.5 3.3 2 1 1 3 3 3 0 Bacteriophage holin family Esterase PF00756.20 ORY18030.1 - 1.9e-05 24.4 0.0 5.7e-05 22.9 0.0 1.9 1 1 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 ORY18030.1 - 0.012 15.1 0.0 1.2 8.6 0.0 2.4 2 0 0 2 2 2 0 Prolyl oligopeptidase family Apc15p PF05841.11 ORY18032.1 - 1.5e-09 38.7 0.6 3.1e-09 37.7 0.1 1.7 2 0 0 2 2 2 1 Apc15p protein THOC7 PF05615.13 ORY18032.1 - 0.01 16.1 1.8 0.021 15.1 1.8 1.4 1 0 0 1 1 1 0 Tho complex subunit 7 DUF2012 PF09430.10 ORY18033.1 - 2.4e-24 85.8 0.0 3.1e-24 85.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) SOP4 PF17081.5 ORY18033.1 - 6.9e-06 25.7 0.1 0.032 13.8 0.0 2.1 2 0 0 2 2 2 2 Suppressor of PMA 1-7 protein DUF4951 PF16309.5 ORY18033.1 - 0.11 12.5 0.0 0.28 11.3 0.0 1.6 1 0 0 1 1 1 0 Domian of unknown function (DUF4951) LRR_8 PF13855.6 ORY18035.1 - 1e-16 60.4 6.3 1.8e-08 34.0 0.2 2.8 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 ORY18035.1 - 2.5e-12 46.8 1.2 2.1e-05 24.8 0.7 3.2 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY18035.1 - 0.00074 19.7 0.4 15 6.6 0.0 4.7 4 0 0 4 4 4 1 Leucine Rich Repeat Helo_like_N PF17111.5 ORY18035.1 - 0.0097 15.3 0.5 0.021 14.2 0.5 1.5 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins LRR_9 PF14580.6 ORY18035.1 - 0.02 14.4 0.1 0.051 13.1 0.1 1.6 1 1 0 1 1 1 0 Leucine-rich repeat LRR_6 PF13516.6 ORY18035.1 - 0.023 14.7 3.0 16 5.9 0.1 4.4 4 0 0 4 4 4 0 Leucine Rich repeat DUF5407 PF17401.2 ORY18035.1 - 4.5 7.6 5.0 1.4 9.2 0.8 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5407) Mito_carr PF00153.27 ORY18036.1 - 2.5e-66 219.7 5.6 3.7e-24 84.5 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF4748 PF15932.5 ORY18036.1 - 0.037 13.8 0.8 0.11 12.3 0.8 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4748) Pec_lyase_C PF00544.19 ORY18039.1 - 4.3e-40 137.5 8.8 6.7e-40 136.9 8.8 1.3 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 ORY18039.1 - 7.4e-05 22.6 14.6 0.0024 17.7 13.1 2.5 1 1 0 1 1 1 1 Right handed beta helix region Ecm33 PF12454.8 ORY18039.1 - 5.7 7.2 5.5 28 5.0 0.1 2.8 3 0 0 3 3 3 0 GPI-anchored cell wall organization protein HET PF06985.11 ORY18040.1 - 2.1e-25 89.8 0.0 7e-25 88.1 0.0 1.9 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) NACHT PF05729.12 ORY18041.1 - 2.8e-08 33.8 0.1 7.4e-08 32.5 0.1 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 ORY18041.1 - 5.6e-08 33.4 0.2 2.8e-07 31.1 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 ORY18041.1 - 7.8e-05 23.0 0.0 0.0002 21.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain Ank_2 PF12796.7 ORY18041.1 - 0.0002 21.9 0.0 0.086 13.4 0.0 3.3 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) RNA_helicase PF00910.22 ORY18041.1 - 0.03 14.7 0.1 0.18 12.2 0.0 2.2 2 0 0 2 2 2 0 RNA helicase NB-ARC PF00931.22 ORY18041.1 - 0.05 12.8 0.0 0.16 11.2 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain DUF2075 PF09848.9 ORY18041.1 - 0.062 12.5 0.0 0.13 11.5 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Ank_4 PF13637.6 ORY18041.1 - 0.093 13.3 0.0 0.46 11.1 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ribosomal_S11 PF00411.19 ORY18042.1 - 3.7e-46 156.0 2.0 4.7e-46 155.7 2.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 NUDIX PF00293.28 ORY18043.1 - 4.4e-09 36.5 0.0 8.9e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain AICARFT_IMPCHas PF01808.18 ORY18044.1 - 1.2e-91 307.3 0.0 1.6e-91 306.8 0.0 1.2 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 ORY18044.1 - 4e-25 87.8 0.0 7.2e-25 87.0 0.0 1.5 1 0 0 1 1 1 1 MGS-like domain HIG_1_N PF04588.13 ORY18045.1 - 4e-05 23.7 0.3 4e-05 23.7 0.3 2.0 2 0 0 2 2 2 1 Hypoxia induced protein conserved region Gly-zipper_YMGG PF13441.6 ORY18045.1 - 0.0018 18.0 1.5 0.0034 17.1 1.5 1.5 1 0 0 1 1 1 1 YMGG-like Gly-zipper Romo1 PF10247.9 ORY18045.1 - 1.1 9.7 5.1 1.4 9.4 1.9 2.2 2 0 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 ERG4_ERG24 PF01222.17 ORY18046.1 - 3.3e-161 536.8 6.6 3.8e-161 536.6 6.6 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 ORY18046.1 - 5.7e-05 22.8 0.2 0.00018 21.1 0.2 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Man-6-P_recep PF02157.15 ORY18047.1 - 1.5e-17 63.6 0.0 2.1e-17 63.1 0.0 1.2 1 0 0 1 1 1 1 Mannose-6-phosphate receptor ATG27 PF09451.10 ORY18047.1 - 2.7e-11 43.9 0.0 9.7e-11 42.0 0.0 1.8 2 0 0 2 2 2 1 Autophagy-related protein 27 CIMR PF00878.18 ORY18047.1 - 0.0012 18.9 0.0 0.0047 17.0 0.0 1.9 2 0 0 2 2 2 1 Cation-independent mannose-6-phosphate receptor repeat Dynamin_N PF00350.23 ORY18048.1 - 6.9e-15 55.5 0.2 9.9e-14 51.7 0.0 3.1 2 1 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 ORY18048.1 - 1.3e-06 28.4 0.0 0.001 19.2 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase CENP-F_leu_zip PF10473.9 ORY18048.1 - 0.00087 19.3 1.3 0.00087 19.3 1.3 4.3 5 0 0 5 5 4 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ABC_tran PF00005.27 ORY18048.1 - 0.0011 19.5 0.1 0.0063 17.0 0.0 2.4 2 0 0 2 2 2 1 ABC transporter RsgA_GTPase PF03193.16 ORY18048.1 - 0.0025 17.7 0.0 0.012 15.5 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase IIGP PF05049.13 ORY18048.1 - 0.0062 15.6 0.0 0.015 14.4 0.0 1.5 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) AAA_16 PF13191.6 ORY18048.1 - 0.031 14.6 0.0 0.27 11.6 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain AIG1 PF04548.16 ORY18048.1 - 0.049 12.9 0.1 0.14 11.5 0.1 1.7 1 0 0 1 1 1 0 AIG1 family AAA_22 PF13401.6 ORY18048.1 - 0.068 13.4 0.0 1.2 9.4 0.0 2.8 2 0 0 2 2 2 0 AAA domain DUF1664 PF07889.12 ORY18048.1 - 1.6 8.8 9.9 32 4.6 0.6 4.4 4 0 0 4 4 4 0 Protein of unknown function (DUF1664) TssO PF17561.2 ORY18048.1 - 1.7 8.8 7.4 3.6 7.7 0.7 3.6 3 0 0 3 3 3 0 Type VI secretion system, TssO ZapB PF06005.12 ORY18048.1 - 2.7 8.5 8.1 6.3 7.3 0.0 3.9 3 0 0 3 3 3 0 Cell division protein ZapB DUF87 PF01935.17 ORY18048.1 - 6.1 6.9 14.2 3.1 7.8 0.1 4.5 4 1 0 4 4 4 0 Helicase HerA, central domain Jnk-SapK_ap_N PF09744.9 ORY18048.1 - 7.3 6.8 13.5 4.7 7.4 0.0 4.6 5 0 0 5 5 5 0 JNK_SAPK-associated protein-1 COesterase PF00135.28 ORY18052.1 - 1.2e-77 262.0 0.1 1.7e-77 261.4 0.1 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 ORY18052.1 - 1e-06 28.8 0.5 1e-05 25.5 0.5 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 ORY18052.1 - 0.058 12.3 0.0 0.54 9.0 0.0 1.9 2 0 0 2 2 2 0 Steryl acetyl hydrolase PhyH PF05721.13 ORY18054.1 - 0.0022 18.3 0.0 0.0042 17.4 0.0 1.4 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Fungal_trans_2 PF11951.8 ORY18055.1 - 2.2e-12 46.5 0.0 2.2e-09 36.6 0.0 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY18055.1 - 2e-08 34.2 12.7 3.3e-08 33.5 12.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.25 ORY18056.1 - 1.8e-24 86.5 0.0 2.1e-24 86.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY18056.1 - 3.9e-17 62.4 0.0 4.4e-17 62.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORY18056.1 - 0.011 14.5 0.0 0.016 14.0 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase APG17 PF04108.12 ORY18110.1 - 1.4e-111 373.5 0.0 1.6e-111 373.3 0.0 1.0 1 0 0 1 1 1 1 Autophagy protein Apg17 Taxilin PF09728.9 ORY18110.1 - 0.0095 15.1 0.4 0.86 8.7 0.7 2.4 2 0 0 2 2 2 1 Myosin-like coiled-coil protein Baculo_PEP_C PF04513.12 ORY18110.1 - 0.041 13.9 4.0 1.4 9.0 0.2 3.2 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus RRF PF01765.19 ORY18110.1 - 0.062 13.3 1.9 1.1 9.2 0.0 3.0 3 0 0 3 3 3 0 Ribosome recycling factor YabA PF06156.13 ORY18110.1 - 0.092 13.4 5.8 3 8.6 0.1 3.5 2 1 0 2 2 2 0 Initiation control protein YabA EzrA PF06160.12 ORY18110.1 - 0.12 10.6 5.6 2.5 6.2 0.8 3.0 3 1 1 4 4 4 0 Septation ring formation regulator, EzrA WD40 PF00400.32 ORY18111.1 - 5.7e-39 131.4 24.0 7.4e-06 26.6 0.3 8.6 8 0 0 8 8 8 6 WD domain, G-beta repeat F-box-like PF12937.7 ORY18111.1 - 4.2e-12 45.7 0.2 8.1e-12 44.8 0.2 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY18111.1 - 1.9e-11 43.5 0.8 8.8e-11 41.4 0.1 2.3 1 1 1 2 2 2 1 F-box domain ANAPC4_WD40 PF12894.7 ORY18111.1 - 3.2e-09 37.0 0.1 0.21 11.9 0.0 5.2 2 2 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ORY18111.1 - 4.1e-06 25.7 4.7 0.084 11.5 0.2 3.7 3 1 0 4 4 4 3 Nucleoporin Nup120/160 F-box_4 PF15966.5 ORY18111.1 - 0.0011 18.9 0.1 0.0039 17.0 0.0 2.0 2 0 0 2 2 2 1 F-box WD40_like PF17005.5 ORY18111.1 - 0.0023 17.3 0.1 0.028 13.8 0.1 2.2 2 1 0 2 2 2 1 WD40-like domain BBS2_Mid PF14783.6 ORY18111.1 - 0.0026 17.8 0.0 0.8 9.8 0.0 3.4 3 1 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region Serglycin PF04360.12 ORY18111.1 - 0.041 13.8 1.5 0.098 12.6 1.5 1.7 1 0 0 1 1 1 0 Serglycin PALB2_WD40 PF16756.5 ORY18111.1 - 0.27 10.1 1.6 15 4.3 0.2 2.9 2 1 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain NAR2 PF16974.5 ORY18111.1 - 2.8 7.3 4.1 4.4 6.7 2.7 1.9 2 0 0 2 2 2 0 High-affinity nitrate transporter accessory Sugar_tr PF00083.24 ORY18113.1 - 1.9e-128 429.2 24.5 2.2e-128 429.0 24.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY18113.1 - 9.4e-24 84.0 63.7 3.2e-22 79.0 34.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_holin_3_2 PF04550.12 ORY18113.1 - 0.26 11.9 5.8 0.38 11.3 4.2 2.1 2 0 0 2 2 2 0 Phage holin family 2 Lig_chan PF00060.26 ORY18113.1 - 2.9 7.7 6.1 0.39 10.6 0.6 2.4 2 1 0 2 2 2 0 Ligand-gated ion channel Zn_clus PF00172.18 ORY18115.1 - 1.6e-08 34.5 9.0 3.8e-08 33.3 9.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ORY18115.1 - 6.7e-07 28.6 0.2 2.6e-06 26.7 0.1 2.0 3 0 0 3 3 3 1 Fungal specific transcription factor domain MFS_1 PF07690.16 ORY18116.1 - 2.2e-30 105.8 28.9 2.2e-30 105.8 28.9 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily PTR2 PF00854.21 ORY18116.1 - 1.8e-06 27.0 4.3 1.8e-06 27.0 4.3 1.6 2 0 0 2 2 2 1 POT family WCOR413 PF05562.11 ORY18116.1 - 0.2 11.6 3.9 0.42 10.5 3.9 1.4 1 0 0 1 1 1 0 Cold acclimation protein WCOR413 C_Hendra PF16821.5 ORY18116.1 - 0.4 10.6 1.8 0.59 10.0 1.8 1.2 1 0 0 1 1 1 0 C protein from hendra and measles viruses FAD_binding_3 PF01494.19 ORY18117.1 - 5.8e-13 48.8 0.2 1.4e-11 44.3 0.2 2.5 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 ORY18117.1 - 3.6e-08 33.0 0.1 1.6e-05 24.3 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ORY18117.1 - 8e-08 31.8 0.1 1.3e-07 31.0 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 ORY18117.1 - 2.8e-06 27.5 0.2 6.7e-06 26.3 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 ORY18117.1 - 1.6e-05 23.8 0.3 6.7e-05 21.8 0.1 1.8 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.24 ORY18117.1 - 3.9e-05 23.4 0.0 0.00017 21.3 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 ORY18117.1 - 5.4e-05 22.7 0.1 8.9e-05 22.0 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 ORY18117.1 - 5.6e-05 22.4 0.0 8.4e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 ORY18117.1 - 0.00037 19.9 0.0 0.00066 19.0 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 ORY18117.1 - 0.0012 19.4 0.6 0.008 16.7 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ORY18117.1 - 0.017 14.4 0.1 0.04 13.2 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 ORY18117.1 - 0.11 11.7 0.1 0.22 10.7 0.1 1.4 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.12 ORY18117.1 - 0.11 11.5 0.7 2.1 7.3 0.0 2.7 3 0 0 3 3 3 0 Lycopene cyclase protein p450 PF00067.22 ORY18118.1 - 3.5e-81 273.3 0.0 4e-81 273.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ACC_central PF08326.12 ORY18120.1 - 3.1e-279 928.3 0.0 3.8e-279 928.0 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.22 ORY18120.1 - 1.1e-187 624.6 0.0 1.5e-187 624.1 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 ORY18120.1 - 1.2e-53 181.8 0.0 2.9e-53 180.5 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 ORY18120.1 - 2.4e-28 98.9 0.1 4.9e-28 97.9 0.1 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 ORY18120.1 - 1.5e-21 76.5 0.0 8.4e-20 70.9 0.0 3.2 4 0 0 4 4 4 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 ORY18120.1 - 1.6e-17 63.1 0.1 3.5e-17 62.0 0.1 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 ORY18120.1 - 0.00033 20.3 0.0 0.0049 16.4 0.0 2.5 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 ORY18120.1 - 0.003 17.6 0.0 0.011 15.8 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp domain GxGYxYP_N PF16216.5 ORY18120.1 - 0.043 14.0 0.0 0.085 13.0 0.0 1.4 1 0 0 1 1 1 0 GxGYxY sequence motif in domain of unknown function N-terminal ATP-grasp PF02222.22 ORY18120.1 - 0.094 12.3 0.0 0.24 11.0 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain NUDE_C PF04880.13 ORY18122.1 - 1.6e-39 136.2 17.6 1.6e-39 136.2 17.6 4.6 2 1 4 6 6 3 1 NUDE protein, C-terminal conserved region ZapB PF06005.12 ORY18122.1 - 0.00019 21.8 7.0 0.00019 21.8 7.0 4.0 2 1 2 4 4 4 1 Cell division protein ZapB WEMBL PF05701.11 ORY18122.1 - 0.022 13.5 23.3 0.029 13.1 23.3 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light TPR_MLP1_2 PF07926.12 ORY18122.1 - 0.059 13.4 35.2 0.6 10.2 10.6 3.4 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein LPP PF04728.13 ORY18122.1 - 0.16 12.3 1.5 0.58 10.6 0.4 2.6 3 0 0 3 3 2 0 Lipoprotein leucine-zipper DUF3584 PF12128.8 ORY18122.1 - 0.18 9.3 23.8 0.24 8.9 23.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Tropomyosin_1 PF12718.7 ORY18122.1 - 0.18 11.9 32.7 5.1 7.2 21.9 3.3 2 1 1 3 3 3 0 Tropomyosin like CENP-F_leu_zip PF10473.9 ORY18122.1 - 0.22 11.6 35.3 0.13 12.3 15.7 3.2 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fez1 PF06818.15 ORY18122.1 - 0.43 11.0 28.3 0.53 10.7 12.6 2.4 1 1 1 2 2 2 0 Fez1 DMPK_coil PF08826.10 ORY18122.1 - 0.45 10.6 30.2 0.28 11.3 3.2 4.6 4 1 1 5 5 4 0 DMPK coiled coil domain like Phage_GP20 PF06810.11 ORY18122.1 - 1.1 9.1 19.0 2 8.2 5.8 3.3 1 1 2 3 3 3 0 Phage minor structural protein GP20 Prominin PF05478.11 ORY18122.1 - 2.2 6.1 6.4 3.1 5.6 6.4 1.3 1 0 0 1 1 1 0 Prominin Fmp27_WPPW PF10359.9 ORY18122.1 - 2.5 6.9 20.2 0.54 9.0 9.7 2.2 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain GAS PF13851.6 ORY18122.1 - 4.3 6.6 30.4 8.6 5.7 18.8 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF16 PF01519.16 ORY18122.1 - 5.3 7.6 19.8 0.1 13.1 6.5 2.4 1 1 1 2 2 2 0 Protein of unknown function DUF16 Methyltransf_2 PF00891.18 ORY18123.1 - 1.7e-30 105.9 0.0 2.8e-30 105.2 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_23 PF13489.6 ORY18123.1 - 0.00058 19.7 0.0 0.001 18.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY18123.1 - 0.0034 18.0 0.0 0.0084 16.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MHB PF16525.5 ORY18123.1 - 0.025 14.8 0.1 0.059 13.6 0.1 1.6 1 0 0 1 1 1 0 Haemophore, haem-binding Methyltransf_12 PF08242.12 ORY18123.1 - 0.025 15.3 0.0 0.053 14.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 ORY18123.1 - 0.14 11.7 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain DUF3328 PF11807.8 ORY18124.1 - 2.5e-17 63.4 1.6 5.2e-17 62.4 1.6 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.8 ORY18125.1 - 1.8e-25 90.0 4.1 2.2e-25 89.7 4.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Pesticin PF16754.5 ORY18126.1 - 1e-05 25.5 2.6 0.79 9.7 0.1 3.0 1 1 2 3 3 3 3 Bacterial toxin homologue of phage lysozyme, C-term SRP_TPR_like PF17004.5 ORY18126.1 - 0.001 19.1 0.0 0.019 15.0 0.0 2.2 1 1 0 1 1 1 1 Putative TPR-like repeat DUF2332 PF10094.9 ORY18126.1 - 0.0018 17.8 0.1 8.7 5.7 0.0 3.0 1 1 2 3 3 3 3 Uncharacterized protein conserved in bacteria (DUF2332) DUF1299 PF06975.11 ORY18126.1 - 0.0092 16.0 2.3 5.9 7.1 0.1 3.2 3 0 0 3 3 3 1 Protein of unknown function (DUF1299) SapB_1 PF05184.15 ORY18126.1 - 0.03 14.4 1.9 31 4.7 0.1 3.1 3 0 0 3 3 3 0 Saposin-like type B, region 1 3-alpha PF03475.14 ORY18126.1 - 0.57 10.1 3.6 16 5.4 0.0 3.3 4 0 0 4 4 4 0 3-alpha domain Cu-binding_MopE PF11617.8 ORY18126.1 - 2 8.6 5.0 1e+02 3.2 0.1 3.2 3 0 0 3 3 3 0 Putative metal-binding motif DUF3328 PF11807.8 ORY18127.1 - 2e-18 67.0 1.9 9.2e-18 64.8 1.9 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) Mito_carr PF00153.27 ORY18128.1 - 1.9e-45 152.7 1.2 1.2e-16 60.3 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein YtxH PF12732.7 ORY18128.1 - 2.1 9.0 4.8 8.7 7.0 1.6 3.0 2 1 0 2 2 2 0 YtxH-like protein p450 PF00067.22 ORY18132.1 - 1.6e-31 109.6 0.0 2.1e-31 109.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 HeLo PF14479.6 ORY18133.1 - 3.1e-06 27.2 0.0 0.0085 16.0 0.0 2.6 2 0 0 2 2 2 2 Prion-inhibition and propagation Pkinase PF00069.25 ORY18133.1 - 0.00068 19.1 0.0 0.0011 18.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain IQ PF00612.27 ORY18133.1 - 0.0036 17.0 2.0 2.3 8.2 0.4 3.1 2 0 0 2 2 2 2 IQ calmodulin-binding motif Pox_ser-thr_kin PF05445.11 ORY18133.1 - 0.049 12.6 0.0 0.073 12.0 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase_Tyr PF07714.17 ORY18133.1 - 0.097 11.9 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Acyltransferase PF01553.21 ORY18134.1 - 4.8e-33 113.7 0.0 7.5e-33 113.0 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase DUF4153 PF13687.6 ORY18134.1 - 0.9 9.1 7.8 1.4 8.5 7.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4153) Tetraspanin PF00335.20 ORY18135.1 - 0.00043 20.1 0.9 0.00072 19.3 0.8 1.5 1 1 0 1 1 1 1 Tetraspanin family MARVEL PF01284.23 ORY18135.1 - 0.00083 19.4 1.0 0.0013 18.7 0.9 1.5 1 1 0 1 1 1 1 Membrane-associating domain 7tm_3 PF00003.22 ORY18135.1 - 0.02 14.7 0.3 0.035 13.8 0.1 1.5 1 1 0 1 1 1 0 7 transmembrane sweet-taste receptor of 3 GCPR DUF3169 PF11368.8 ORY18135.1 - 0.041 13.4 0.4 0.2 11.1 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) SUR7 PF06687.12 ORY18135.1 - 0.049 13.3 2.7 0.21 11.2 1.1 2.1 1 1 1 2 2 2 0 SUR7/PalI family Shugoshin_C PF07557.11 ORY18136.1 - 0.081 12.7 2.5 0.19 11.6 2.5 1.6 1 0 0 1 1 1 0 Shugoshin C terminus Glyoxalase PF00903.25 ORY18137.1 - 9.4e-11 42.0 0.0 1.2e-10 41.6 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 ORY18137.1 - 8.9e-06 25.9 0.0 2.6e-05 24.5 0.0 1.6 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 ORY18137.1 - 0.0001 22.5 0.0 0.00024 21.3 0.0 1.6 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_6 PF18029.1 ORY18137.1 - 0.0014 19.4 0.0 0.0021 18.9 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase-like domain adh_short_C2 PF13561.6 ORY18138.1 - 2.1e-60 204.2 0.5 2.6e-60 203.9 0.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY18138.1 - 4.3e-48 163.4 0.3 5.6e-48 163.0 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORY18138.1 - 4.7e-14 52.7 0.2 7e-14 52.1 0.2 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 ORY18138.1 - 0.069 13.0 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 ORY18138.1 - 0.1 12.2 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain p450 PF00067.22 ORY18140.1 - 3.3e-50 171.2 0.0 4.2e-50 170.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 RICTOR_N PF14664.6 ORY18140.1 - 0.19 10.7 0.0 0.26 10.2 0.0 1.1 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, N-term Methyltransf_23 PF13489.6 ORY18141.1 - 2.8e-15 56.5 0.0 4e-15 56.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY18141.1 - 2.9e-09 37.5 0.0 6.4e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY18141.1 - 5.8e-07 30.1 0.0 1.6e-06 28.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY18141.1 - 1.2e-06 28.4 0.2 2.4e-05 24.1 0.2 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY18141.1 - 0.00018 22.2 0.0 0.0013 19.5 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 ORY18141.1 - 0.017 15.2 0.0 0.025 14.7 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_4 PF02390.17 ORY18141.1 - 0.019 14.4 0.0 0.033 13.6 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase MTS PF05175.14 ORY18141.1 - 0.042 13.4 0.0 0.085 12.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain CMAS PF02353.20 ORY18141.1 - 0.095 12.0 0.0 0.18 11.0 0.0 1.5 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase adh_short_C2 PF13561.6 ORY18142.1 - 7.7e-26 91.1 0.0 9.7e-26 90.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY18142.1 - 1.6e-18 66.8 0.0 2.1e-18 66.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORY18142.1 - 0.0019 18.1 0.1 0.003 17.5 0.1 1.4 1 1 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.8 ORY18142.1 - 0.05 13.4 0.2 0.088 12.6 0.2 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ELFV_dehydrog_N PF02812.18 ORY18142.1 - 0.11 12.3 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain EMC1_C PF07774.13 ORY18143.1 - 6.6e-73 244.9 0.0 1.6e-72 243.7 0.0 1.7 1 0 0 1 1 1 1 ER membrane protein complex subunit 1, C-terminal PQQ_2 PF13360.6 ORY18143.1 - 1.8e-32 112.8 5.0 3.6e-29 102.0 1.1 2.8 3 0 0 3 3 3 2 PQQ-like domain PQQ PF01011.21 ORY18143.1 - 0.00084 19.2 2.3 21 5.3 0.0 6.3 7 1 1 8 8 8 1 PQQ enzyme repeat Ras PF00071.22 ORY18144.1 - 6.4e-51 172.2 0.0 7.5e-51 171.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY18144.1 - 1.1e-18 67.5 0.0 1.6e-18 67.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY18144.1 - 5.4e-08 32.5 0.0 6e-08 32.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 ORY18144.1 - 0.00041 19.9 0.0 0.0078 15.8 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 ORY18144.1 - 0.00048 20.2 0.0 0.00075 19.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ORY18144.1 - 0.0012 18.8 0.1 0.72 9.7 0.1 2.3 1 1 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 ORY18144.1 - 0.018 15.3 0.1 0.83 9.9 0.0 2.4 1 1 0 2 2 2 0 AAA domain DEAD PF00270.29 ORY18147.1 - 9.4e-37 126.5 0.3 1.5e-36 125.8 0.3 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY18147.1 - 3.5e-28 98.1 0.1 2e-27 95.8 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY18147.1 - 0.00022 21.3 0.0 0.00062 19.8 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 ORY18147.1 - 0.0016 18.8 0.1 0.0044 17.4 0.1 1.7 1 1 0 1 1 1 1 AAA domain NPR3 PF03666.13 ORY18147.1 - 0.062 12.1 3.2 0.1 11.3 3.2 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Presenilin PF01080.17 ORY18147.1 - 0.072 11.8 4.5 0.11 11.2 4.5 1.2 1 0 0 1 1 1 0 Presenilin Flavi_DEAD PF07652.14 ORY18147.1 - 0.11 12.5 0.1 0.21 11.6 0.1 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain CPSF100_C PF13299.6 ORY18147.1 - 8.8 6.5 8.1 15 5.7 4.3 2.3 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal HET PF06985.11 ORY18148.1 - 3.7e-15 56.5 4.7 6.5e-13 49.3 0.4 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) adh_short_C2 PF13561.6 ORY18150.1 - 8.6e-59 198.9 0.1 9.6e-59 198.8 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY18150.1 - 1.2e-50 171.7 1.4 1.5e-50 171.4 1.4 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORY18150.1 - 2.1e-13 50.6 1.8 2.9e-13 50.1 1.8 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 ORY18150.1 - 0.022 14.7 0.4 0.036 14.0 0.4 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Fungal_trans PF04082.18 ORY18151.1 - 1.1e-20 73.8 0.0 1.6e-20 73.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Striatin PF08232.12 ORY18151.1 - 0.4 11.3 2.3 4.6 7.8 0.5 2.3 2 0 0 2 2 2 0 Striatin family BTB PF00651.31 ORY18152.1 - 2.5e-08 34.1 0.5 3.8e-07 30.3 0.1 2.2 2 0 0 2 2 2 1 BTB/POZ domain DUF5437 PF17505.2 ORY18152.1 - 0.031 14.3 0.2 0.064 13.3 0.2 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5437) eIF-4B PF06273.11 ORY18152.1 - 0.14 11.2 0.7 0.2 10.7 0.7 1.1 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B PUL PF08324.11 ORY18153.1 - 8.2e-65 218.8 0.8 1.3e-64 218.1 0.8 1.3 1 0 0 1 1 1 1 PUL domain PFU PF09070.11 ORY18153.1 - 1.5e-44 150.8 0.7 3e-44 149.9 0.7 1.5 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.32 ORY18153.1 - 1.1e-31 108.4 13.0 2e-07 31.6 0.0 7.6 7 0 0 7 7 7 5 WD domain, G-beta repeat BBS2_Mid PF14783.6 ORY18153.1 - 0.018 15.0 0.0 1.7 8.7 0.0 3.3 1 1 2 3 3 3 0 Ciliary BBSome complex subunit 2, middle region ANAPC4_WD40 PF12894.7 ORY18153.1 - 0.028 14.7 0.9 36 4.8 0.0 4.0 4 1 1 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain DUF2237 PF09996.9 ORY18155.1 - 6.6e-21 74.5 0.0 9e-21 74.0 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2237) MFS_1 PF07690.16 ORY18156.1 - 8.4e-41 140.1 79.6 5.6e-40 137.4 50.0 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 ORY18156.1 - 1.6e-10 40.0 10.5 1.6e-10 40.0 10.5 2.2 1 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) GET2 PF08690.10 ORY18156.1 - 0.14 11.8 0.0 0.14 11.8 0.0 1.4 2 0 0 2 2 2 0 GET complex subunit GET2 DUF5337 PF17272.2 ORY18156.1 - 0.65 9.9 2.8 3.9 7.4 1.1 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF5337) adh_short_C2 PF13561.6 ORY18157.1 - 7.1e-46 156.7 0.0 5.2e-44 150.6 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY18157.1 - 9e-32 110.1 0.0 3.9e-31 108.0 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORY18157.1 - 0.00017 21.6 0.0 0.00069 19.6 0.0 1.8 2 0 0 2 2 2 1 KR domain PSP PF04046.16 ORY18157.1 - 0.03 14.2 0.1 0.095 12.6 0.1 1.9 1 0 0 1 1 1 0 PSP BTB PF00651.31 ORY18158.1 - 1.3e-12 47.9 0.0 3.3e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain BET PF17035.5 ORY18158.1 - 0.011 15.9 1.1 0.13 12.5 1.1 2.2 1 1 0 1 1 1 0 Bromodomain extra-terminal - transcription regulation Glyco_hydro_64 PF16483.5 ORY18159.1 - 4.5e-135 450.7 0.2 5.4e-135 450.4 0.2 1.0 1 0 0 1 1 1 1 Beta-1,3-glucanase HEV_ORF1 PF02444.16 ORY18159.1 - 0.017 15.7 1.6 0.48 11.0 0.2 2.5 2 0 0 2 2 2 0 Hepatitis E virus ORF-2 (Putative capsid protein) BTB PF00651.31 ORY18160.1 - 3.9e-10 40.0 0.0 3.5e-09 36.9 0.0 2.3 2 1 1 3 3 3 1 BTB/POZ domain AtuA PF07287.11 ORY18161.1 - 1.8e-125 418.3 0.0 2.4e-125 417.9 0.0 1.1 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA MFS_1 PF07690.16 ORY18162.1 - 1.8e-25 89.6 29.8 5.4e-25 88.1 28.7 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily PARP PF00644.20 ORY18164.1 - 8.8e-11 41.8 0.0 5e-10 39.3 0.0 2.3 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain NmrA PF05368.13 ORY18166.1 - 6.7e-23 81.4 0.1 8.5e-23 81.1 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ORY18166.1 - 1.5e-14 54.4 0.0 3.7e-14 53.0 0.0 1.7 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 ORY18166.1 - 3.5e-06 26.7 0.1 0.00014 21.4 0.0 2.2 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 ORY18166.1 - 0.1 12.7 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase CoA_binding_2 PF13380.6 ORY18166.1 - 0.14 12.7 0.1 0.49 10.9 0.0 2.0 2 0 0 2 2 2 0 CoA binding domain Acetyltransf_3 PF13302.7 ORY18167.1 - 8.7e-20 71.8 0.0 1.1e-19 71.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORY18167.1 - 1.1e-06 28.8 0.0 1.7e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 ORY18167.1 - 0.0026 17.7 0.0 0.22 11.5 0.0 2.3 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_8 PF13523.6 ORY18167.1 - 0.12 12.1 0.0 0.26 11.0 0.0 1.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Lipase_GDSL_2 PF13472.6 ORY18168.1 - 3.7e-15 56.8 1.8 4.7e-15 56.4 1.8 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 ORY18168.1 - 1.2e-06 28.6 0.5 1.8e-06 28.1 0.5 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DUF4149 PF13664.6 ORY18169.1 - 2e-20 73.0 0.3 2e-20 73.0 0.3 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) Fungal_trans PF04082.18 ORY18170.1 - 3.7e-08 32.7 0.4 9.8e-07 28.1 0.4 2.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY18170.1 - 0.052 13.7 13.1 0.11 12.7 13.1 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain NACHT PF05729.12 ORY18172.1 - 9.1e-06 25.7 0.0 1.3e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 ORY18172.1 - 0.00025 21.3 0.0 0.00045 20.5 0.0 1.4 1 1 0 1 1 1 1 AAA domain ATP_bind_1 PF03029.17 ORY18172.1 - 0.092 12.5 0.0 0.23 11.2 0.0 1.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 ORY18172.1 - 0.18 12.2 0.0 0.28 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain PIG-P PF08510.12 ORY18173.1 - 0.2 11.6 3.8 0.38 10.7 3.8 1.4 1 0 0 1 1 1 0 PIG-P DUF676 PF05057.14 ORY18174.1 - 0.00016 21.3 0.0 0.00026 20.6 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) NACHT PF05729.12 ORY18174.1 - 0.0049 16.8 0.0 0.0095 15.9 0.0 1.5 1 0 0 1 1 1 1 NACHT domain Glycos_transf_N PF04413.16 ORY18174.1 - 0.031 13.9 0.0 0.076 12.7 0.0 1.6 1 0 0 1 1 1 0 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) DUF829 PF05705.14 ORY18174.1 - 0.058 13.3 0.0 0.094 12.6 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF829) Torsin PF06309.11 ORY18174.1 - 0.14 12.3 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 Torsin Ank_2 PF12796.7 ORY18175.1 - 7.2e-07 29.7 0.0 9.7e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY18175.1 - 1.5e-05 25.4 0.0 2e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 ORY18175.1 - 8.2e-05 22.9 0.0 0.25 11.9 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 ORY18175.1 - 0.00015 21.9 0.0 0.34 11.6 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 ORY18175.1 - 0.021 15.2 0.0 0.14 12.5 0.0 1.9 1 1 1 2 2 2 0 Ankyrin repeats (many copies) DUF1843 PF08898.10 ORY18175.1 - 0.025 15.1 0.5 0.74 10.4 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF1843) Ank_2 PF12796.7 ORY18176.1 - 3.6e-15 56.3 0.3 3.8e-08 33.8 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY18176.1 - 1.5e-13 50.9 0.1 2e-05 25.1 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 ORY18176.1 - 1.6e-11 44.1 4.7 0.0086 16.5 0.1 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.6 ORY18176.1 - 3.5e-11 42.3 1.5 0.13 12.9 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 ORY18176.1 - 6.7e-05 23.1 0.7 0.69 10.3 0.1 3.0 2 1 1 3 3 3 3 Ankyrin repeats (many copies) HTH_7 PF02796.15 ORY18176.1 - 0.0099 15.9 0.0 0.036 14.2 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase DUF1843 PF08898.10 ORY18176.1 - 0.018 15.5 2.1 9.8 6.8 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1843) DUF5620 PF18522.1 ORY18176.1 - 0.17 12.3 0.0 0.19 12.1 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF5620) ChiW_Ig_like PF18683.1 ORY18176.1 - 0.2 11.9 3.3 0.29 11.4 0.7 2.4 2 1 1 3 3 3 0 Chitinase W immunoglobulin-like domain ABC_membrane PF00664.23 ORY18177.1 - 8.4e-81 271.6 39.4 1e-44 153.2 10.9 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 ORY18177.1 - 6.3e-64 214.6 0.0 9.4e-32 110.4 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 ORY18177.1 - 1.9e-19 70.0 1.1 1.7e-05 24.3 0.0 4.2 4 0 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 ORY18177.1 - 5.7e-08 33.1 0.9 0.054 13.8 0.0 4.3 4 1 0 4 4 3 2 AAA domain AAA_16 PF13191.6 ORY18177.1 - 5.7e-08 33.3 0.4 0.031 14.7 0.0 3.4 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 ORY18177.1 - 8.5e-08 31.8 0.3 0.00053 19.7 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 ORY18177.1 - 1.5e-07 31.4 0.0 0.0024 17.8 0.0 2.9 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 ORY18177.1 - 4.9e-07 30.5 0.2 0.0043 17.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 ORY18177.1 - 9.2e-06 25.5 0.0 0.51 10.0 0.0 3.6 3 0 0 3 3 3 2 AAA domain AAA_15 PF13175.6 ORY18177.1 - 1.3e-05 25.1 0.0 0.074 12.7 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.6 ORY18177.1 - 2e-05 24.2 0.0 0.38 10.3 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_21 PF13304.6 ORY18177.1 - 2.2e-05 24.4 0.7 0.31 10.8 0.0 3.1 2 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system Rad17 PF03215.15 ORY18177.1 - 9.6e-05 22.4 0.1 0.54 10.1 0.0 2.6 2 0 0 2 2 2 2 Rad17 P-loop domain SbcCD_C PF13558.6 ORY18177.1 - 0.00011 22.4 1.0 0.15 12.3 0.1 3.5 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA PF00004.29 ORY18177.1 - 0.00013 22.4 0.6 4.6 7.7 0.0 4.2 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) ATP-synt_ab PF00006.25 ORY18177.1 - 0.00027 20.6 0.8 0.87 9.2 0.1 3.0 2 2 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain AAA_5 PF07728.14 ORY18177.1 - 0.0005 20.1 0.2 2.7 8.0 0.0 3.6 4 0 0 4 4 3 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 ORY18177.1 - 0.0015 19.1 0.0 3.2 8.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 ORY18177.1 - 0.0016 18.0 0.0 1.6 8.2 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region DUF87 PF01935.17 ORY18177.1 - 0.002 18.3 0.6 1.3 9.1 0.2 2.9 3 0 0 3 3 3 1 Helicase HerA, central domain AAA_24 PF13479.6 ORY18177.1 - 0.0033 17.2 0.0 1.7 8.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 ORY18177.1 - 0.01 16.2 0.0 13 6.3 0.0 3.3 3 0 0 3 3 2 0 RNA helicase AAA_28 PF13521.6 ORY18177.1 - 0.012 15.8 0.2 4.1 7.6 0.0 2.8 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.20 ORY18177.1 - 0.015 14.5 0.0 0.83 8.7 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit Zeta_toxin PF06414.12 ORY18177.1 - 0.021 14.1 0.1 3 7.1 0.0 2.9 3 0 0 3 3 3 0 Zeta toxin TniB PF05621.11 ORY18177.1 - 0.024 14.1 0.0 3.8 6.9 0.0 2.7 3 0 0 3 3 2 0 Bacterial TniB protein PRK PF00485.18 ORY18177.1 - 0.031 14.0 0.2 7.3 6.3 0.0 2.8 3 0 0 3 3 3 0 Phosphoribulokinase / Uridine kinase family AAA_11 PF13086.6 ORY18177.1 - 0.049 13.4 0.1 9.6 5.9 0.0 2.7 2 1 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 ORY18177.1 - 0.051 13.3 0.4 17 5.1 0.0 3.7 4 0 0 4 4 4 0 IstB-like ATP binding protein ATP_bind_1 PF03029.17 ORY18177.1 - 0.066 13.0 0.0 1.8 8.3 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 ORY18177.1 - 0.078 13.1 0.0 17 5.5 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_33 PF13671.6 ORY18177.1 - 0.08 13.1 0.1 6.8 6.8 0.1 2.8 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 ORY18177.1 - 0.09 13.1 0.7 11 6.4 0.0 3.1 3 0 0 3 3 2 0 AAA domain Gp138_N PF18352.1 ORY18177.1 - 0.091 12.8 0.0 2.6 8.2 0.0 2.5 2 0 0 2 2 2 0 Phage protein Gp138 N-terminal domain NB-ARC PF00931.22 ORY18177.1 - 0.12 11.5 0.1 11 5.1 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain DUF2095 PF09868.9 ORY18177.1 - 0.14 12.1 0.1 27 4.8 0.0 2.9 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2095) FSH1 PF03959.13 ORY18178.1 - 3e-25 89.1 0.0 5e-25 88.4 0.0 1.3 1 1 0 1 1 1 1 Serine hydrolase (FSH1) ketoacyl-synt PF00109.26 ORY18179.1 - 3.4e-64 216.9 0.0 6.6e-64 215.9 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 ORY18179.1 - 1e-60 204.8 0.5 2.8e-60 203.3 0.1 2.1 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.21 ORY18179.1 - 1.4e-54 185.7 0.0 2.4e-54 185.0 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 ORY18179.1 - 6.1e-47 160.3 0.0 9.4e-47 159.7 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 ORY18179.1 - 9.9e-37 125.6 0.0 3.8e-36 123.7 0.0 2.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 ORY18179.1 - 7e-19 68.3 0.0 2.5e-18 66.6 0.0 2.1 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 ORY18179.1 - 3.2e-11 43.0 0.1 9e-11 41.6 0.1 1.8 1 0 0 1 1 1 1 short chain dehydrogenase PP-binding PF00550.25 ORY18179.1 - 7.8e-09 35.8 1.2 1.3e-08 35.0 0.1 2.1 2 0 0 2 2 1 1 Phosphopantetheine attachment site ADH_zinc_N PF00107.26 ORY18179.1 - 1.2e-07 31.8 0.2 7.3e-07 29.2 0.0 2.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ORY18179.1 - 2.5e-06 28.6 0.1 1e-05 26.6 0.1 2.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Thiolase_N PF00108.23 ORY18179.1 - 7.7e-06 25.4 0.1 1.9e-05 24.2 0.1 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain ADH_N PF08240.12 ORY18179.1 - 8.5e-05 22.4 0.1 0.00019 21.3 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain SAT PF16073.5 ORY18179.1 - 0.024 14.4 0.3 0.076 12.7 0.3 1.8 1 1 0 1 1 1 0 Starter unit:ACP transacylase in aflatoxin biosynthesis GDP_Man_Dehyd PF16363.5 ORY18179.1 - 0.049 13.0 0.0 0.089 12.2 0.0 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase YjeF_N PF03853.15 ORY18179.1 - 0.051 13.5 0.1 6.4 6.6 0.0 2.6 2 0 0 2 2 2 0 YjeF-related protein N-terminus NmrA PF05368.13 ORY18179.1 - 0.16 11.5 3.4 0.83 9.2 0.0 3.1 3 0 0 3 3 3 0 NmrA-like family BTB PF00651.31 ORY18183.1 - 5.9e-06 26.5 0.0 1.2e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain PNTB PF02233.16 ORY18184.1 - 8.4e-176 585.4 25.7 8.4e-176 585.4 25.7 2.1 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.21 ORY18184.1 - 8e-73 244.3 0.3 2.2e-72 242.9 0.3 1.8 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 ORY18184.1 - 4.6e-45 153.3 0.3 2.5e-44 150.9 0.0 2.1 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain PNTB_4TM PF12769.7 ORY18184.1 - 6.4e-30 103.5 4.0 6.4e-30 103.5 4.0 4.9 4 1 1 5 5 5 1 4TM region of pyridine nucleotide transhydrogenase, mitoch TPP_enzyme_M PF00205.22 ORY18184.1 - 0.017 14.9 0.2 0.093 12.5 0.2 2.3 1 1 0 1 1 1 0 Thiamine pyrophosphate enzyme, central domain 2-Hacid_dh_C PF02826.19 ORY18184.1 - 0.032 13.6 0.8 0.75 9.1 0.1 2.8 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GIDA PF01134.22 ORY18184.1 - 0.062 12.4 0.6 0.11 11.5 0.6 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A Fumerase PF05681.14 ORY18184.1 - 0.091 12.2 0.1 0.16 11.4 0.1 1.3 1 0 0 1 1 1 0 Fumarate hydratase (Fumerase) Mur_ligase PF01225.25 ORY18184.1 - 0.17 12.2 0.5 10 6.5 0.0 3.4 3 0 0 3 3 3 0 Mur ligase family, catalytic domain Pyr_redox_2 PF07992.14 ORY18184.1 - 0.24 10.6 4.5 0.13 11.4 1.4 2.1 2 1 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORY18184.1 - 1.7 9.0 5.7 0.36 11.1 0.7 2.6 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain DUF4171 PF13775.6 ORY18185.1 - 0.016 15.6 0.4 0.022 15.2 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4171) PHD PF00628.29 ORY18186.1 - 4.4e-10 39.3 1.4 1.1e-09 38.0 1.4 1.7 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 ORY18186.1 - 0.042 13.4 2.0 0.075 12.6 2.0 1.4 1 0 0 1 1 1 0 PHD-finger Catalase PF00199.19 ORY18187.1 - 5.7e-173 575.4 0.1 7e-173 575.1 0.1 1.0 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 ORY18187.1 - 1.3e-15 57.4 0.0 3.1e-15 56.1 0.0 1.7 1 0 0 1 1 1 1 Catalase-related immune-responsive BTB PF00651.31 ORY18188.1 - 9.6e-13 48.3 0.1 2.1e-12 47.3 0.1 1.6 1 1 0 1 1 1 1 BTB/POZ domain CC190 PF15768.5 ORY18188.1 - 0.13 12.3 0.1 0.19 11.8 0.1 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 190 Recep_L_domain PF01030.24 ORY18191.1 - 5.5e-05 23.2 4.8 0.47 10.6 0.2 3.9 1 1 1 3 3 3 3 Receptor L domain Cerato-platanin PF07249.12 ORY18193.1 - 8.1e-07 29.2 0.2 8.1e-07 29.2 0.2 2.0 1 1 1 2 2 2 1 Cerato-platanin STAG PF08514.11 ORY18196.1 - 0.039 13.9 2.7 4.8 7.1 0.1 2.4 2 0 0 2 2 2 0 STAG domain Ribonuc_red_lgN PF00317.21 ORY18196.1 - 0.15 12.1 0.0 0.77 9.8 0.0 2.1 1 1 0 1 1 1 0 Ribonucleotide reductase, all-alpha domain PhoR PF11808.8 ORY18196.1 - 3.7 8.0 10.1 1.7 9.1 0.1 3.1 3 0 0 3 3 3 0 Phosphate regulon sensor protein PhoR Patatin PF01734.22 ORY18197.1 - 2.4e-21 76.9 0.0 4e-21 76.1 0.0 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase Zn_clus PF00172.18 ORY18200.1 - 3.5e-07 30.2 4.9 6.9e-07 29.3 4.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF724 PF05266.14 ORY18204.1 - 0.082 12.7 12.5 0.013 15.3 6.1 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF724) Syntaxin-6_N PF09177.11 ORY18204.1 - 0.091 13.3 7.9 0.049 14.2 4.3 2.4 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Endonuc_Holl PF10107.9 ORY18204.1 - 0.27 11.1 2.3 0.59 10.0 2.3 1.5 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase DUF4407 PF14362.6 ORY18204.1 - 0.61 9.4 7.4 1.1 8.6 7.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) NPV_P10 PF05531.12 ORY18204.1 - 1.6 9.2 4.4 5.4 7.6 1.7 3.1 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein ATF7IP_BD PF16788.5 ORY18204.1 - 2 8.5 11.2 0.44 10.6 0.8 2.3 2 0 0 2 2 2 0 ATF-interacting protein binding domain Fez1 PF06818.15 ORY18204.1 - 2 8.8 16.5 14 6.0 16.5 2.2 1 1 0 1 1 1 0 Fez1 COG2 PF06148.11 ORY18204.1 - 2.6 8.1 7.4 0.48 10.5 2.9 2.1 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 UPF0242 PF06785.11 ORY18204.1 - 2.6 8.1 18.5 0.16 12.0 9.8 2.4 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Baculo_PEP_C PF04513.12 ORY18204.1 - 4.8 7.2 6.2 1.3 9.0 2.0 2.2 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2203 PF09969.9 ORY18204.1 - 8.9 7.1 11.5 13 6.5 4.7 3.2 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) APG6_N PF17675.1 ORY18205.1 - 3.9 8.0 9.4 14 6.3 0.7 3.6 3 1 1 4 4 4 0 Apg6 coiled-coil region Peptidase_S8 PF00082.22 ORY18207.1 - 2.6e-08 33.5 1.3 1.1e-07 31.4 1.2 2.0 2 1 0 2 2 2 1 Subtilase family TPR_1 PF00515.28 ORY18211.1 - 5.6e-41 136.7 15.1 7e-09 35.1 0.0 9.4 9 0 0 9 9 9 6 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY18211.1 - 1.8e-32 111.4 12.4 5.2e-21 74.7 0.2 5.1 5 0 0 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 ORY18211.1 - 5.3e-31 104.2 21.8 1.8e-07 30.7 0.1 9.8 10 0 0 10 10 9 5 Tetratricopeptide repeat TPR_8 PF13181.6 ORY18211.1 - 4.2e-30 101.4 9.2 3.1e-06 27.0 0.0 9.1 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_14 PF13428.6 ORY18211.1 - 3.2e-22 77.3 15.2 0.00059 20.5 0.0 8.9 6 2 3 9 9 9 5 Tetratricopeptide repeat TPR_16 PF13432.6 ORY18211.1 - 3.8e-22 78.7 20.7 5.3e-05 23.8 0.0 7.6 7 1 1 8 8 8 5 Tetratricopeptide repeat TPR_11 PF13414.6 ORY18211.1 - 4.7e-21 74.2 14.9 0.00014 21.4 0.2 9.3 5 2 5 10 10 10 6 TPR repeat TPR_12 PF13424.6 ORY18211.1 - 2.9e-20 72.3 11.0 0.0014 18.9 0.0 7.7 6 1 2 8 8 8 6 Tetratricopeptide repeat TPR_19 PF14559.6 ORY18211.1 - 4.4e-18 65.6 12.2 0.0021 18.5 0.0 7.3 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_7 PF13176.6 ORY18211.1 - 8.2e-17 59.9 10.2 0.00059 19.7 0.0 7.4 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_17 PF13431.6 ORY18211.1 - 4.4e-15 54.9 12.4 0.57 10.7 0.0 9.5 9 1 1 10 10 9 2 Tetratricopeptide repeat TPR_9 PF13371.6 ORY18211.1 - 5.3e-10 39.3 3.8 0.0088 16.2 0.1 5.1 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 ORY18211.1 - 2.2e-09 37.3 11.9 0.56 11.0 0.1 8.6 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_10 PF13374.6 ORY18211.1 - 0.00011 21.9 3.2 1.5 8.8 0.1 5.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_15 PF13429.6 ORY18211.1 - 0.0026 17.0 9.2 2 7.6 0.3 4.8 3 1 1 5 5 5 1 Tetratricopeptide repeat FAT PF02259.23 ORY18211.1 - 0.0057 15.9 0.7 0.036 13.3 0.6 2.3 1 1 0 1 1 1 1 FAT domain TPR_21 PF09976.9 ORY18211.1 - 0.028 14.1 7.3 6.5 6.4 0.6 4.1 3 1 1 4 4 4 0 Tetratricopeptide repeat-like domain RPN7 PF10602.9 ORY18211.1 - 0.083 12.6 1.7 9.6 5.9 0.1 3.6 3 0 0 3 3 3 0 26S proteasome subunit RPN7 DUF5113 PF17140.4 ORY18211.1 - 0.21 11.4 2.8 6.4 6.6 1.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5113) SNAP PF14938.6 ORY18211.1 - 1.5 8.1 4.5 19 4.6 0.0 3.2 2 1 0 2 2 2 0 Soluble NSF attachment protein, SNAP TPR_3 PF07720.12 ORY18211.1 - 6 7.0 6.0 2.8 8.1 0.1 3.5 3 1 0 3 3 3 0 Tetratricopeptide repeat BTAD PF03704.17 ORY18211.1 - 6.5 7.2 12.1 15 6.0 0.1 4.6 4 1 0 5 5 5 0 Bacterial transcriptional activator domain TMEM208_SND2 PF05620.11 ORY18212.1 - 3.9e-51 173.2 0.1 4.4e-51 173.0 0.1 1.0 1 0 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 DUF2142 PF09913.9 ORY18212.1 - 0.0096 14.8 0.3 0.013 14.3 0.3 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2142) CoA_binding_3 PF13727.6 ORY18212.1 - 0.18 11.8 0.2 0.18 11.8 0.2 1.6 2 0 0 2 2 2 0 CoA-binding domain Bot1p PF12298.8 ORY18213.1 - 7.4e-55 185.8 0.6 7.4e-55 185.8 0.6 2.0 2 0 0 2 2 2 1 Eukaryotic mitochondrial regulator protein YqfQ PF14181.6 ORY18213.1 - 0.49 10.6 3.1 1.1 9.4 3.1 1.5 1 0 0 1 1 1 0 YqfQ-like protein RRM_1 PF00076.22 ORY18214.1 - 1.3e-17 63.4 0.0 1.5e-13 50.4 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 ORY18214.1 - 0.089 12.7 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Occluded RNA-recognition motif RRM_Rrp7 PF17799.1 ORY18214.1 - 0.16 11.7 0.0 0.35 10.7 0.0 1.5 1 0 0 1 1 1 0 Rrp7 RRM-like N-terminal domain Ank_4 PF13637.6 ORY18217.1 - 7.8e-16 58.2 0.1 1.2e-11 44.9 0.1 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 ORY18217.1 - 1.9e-13 50.8 0.1 2.4e-13 50.5 0.1 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ORY18217.1 - 7e-13 48.5 3.6 5.7e-07 29.7 0.7 2.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 ORY18217.1 - 2.7e-11 43.4 0.5 0.0027 18.1 0.1 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 ORY18217.1 - 7e-08 32.2 0.1 0.46 11.2 0.1 3.1 3 0 0 3 3 3 3 Ankyrin repeat Abhydrolase_3 PF07859.13 ORY18218.1 - 6.6e-47 160.1 0.0 9.6e-47 159.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 ORY18218.1 - 0.0002 20.4 0.0 0.00044 19.3 0.0 1.5 1 1 0 1 1 1 1 Carboxylesterase family Hydrolase_4 PF12146.8 ORY18218.1 - 0.099 11.9 0.0 0.33 10.2 0.0 1.7 2 0 0 2 2 2 0 Serine aminopeptidase, S33 adh_short PF00106.25 ORY18219.1 - 6.1e-45 153.1 0.0 7.8e-45 152.7 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY18219.1 - 6.2e-42 143.8 0.1 1.1e-41 143.0 0.1 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY18219.1 - 3.2e-11 43.5 0.1 4.4e-11 43.0 0.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ORY18219.1 - 2.8e-05 23.7 0.0 5.4e-05 22.8 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 ORY18219.1 - 0.00054 19.2 0.0 0.00075 18.7 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 ORY18219.1 - 0.014 15.3 0.1 0.059 13.3 0.1 1.9 1 1 0 1 1 1 0 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 ORY18219.1 - 0.022 14.2 0.0 0.039 13.4 0.0 1.5 1 1 1 2 2 2 0 GDP-mannose 4,6 dehydratase DUF998 PF06197.13 ORY18219.1 - 0.26 10.9 8.4 0.017 14.7 2.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF998) FAD_binding_6 PF00970.24 ORY18220.1 - 1.4e-31 108.7 0.0 2.2e-31 108.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 ORY18220.1 - 2.3e-26 92.6 0.0 3.8e-26 91.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 ORY18220.1 - 2.2e-05 24.6 0.0 0.013 15.6 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain DUF2742 PF10888.8 ORY18221.1 - 0.17 12.2 0.0 0.25 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2742) Astacin PF01400.24 ORY18222.1 - 1.4e-12 47.7 2.2 2.8e-09 36.9 0.1 3.5 3 2 0 3 3 3 2 Astacin (Peptidase family M12A) Reprolysin_5 PF13688.6 ORY18222.1 - 0.0021 18.2 0.1 0.0049 17.1 0.0 1.7 1 1 1 2 2 2 1 Metallo-peptidase family M12 Peptidase_M66 PF10462.9 ORY18222.1 - 0.0032 16.5 0.3 0.0032 16.5 0.3 1.5 2 0 0 2 2 2 1 Peptidase M66 Reprolysin_3 PF13582.6 ORY18222.1 - 0.0095 16.5 0.5 0.018 15.6 0.5 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 ORY18222.1 - 0.019 14.6 0.6 0.036 13.7 0.1 1.6 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 ORY18222.1 - 0.022 14.6 3.8 0.088 12.7 3.6 2.1 1 1 0 1 1 1 0 Matrixin Reprolysin PF01421.19 ORY18222.1 - 0.057 13.3 0.0 0.19 11.6 0.0 1.7 2 0 0 2 2 2 0 Reprolysin (M12B) family zinc metalloprotease Peptidase_M57 PF12388.8 ORY18222.1 - 0.14 11.7 1.0 0.93 9.1 0.3 2.1 2 0 0 2 2 2 0 Dual-action HEIGH metallo-peptidase Metallopep PF12044.8 ORY18222.1 - 0.15 10.6 0.7 0.35 9.4 0.3 1.6 2 0 0 2 2 2 0 Putative peptidase family DUF4953 PF16313.5 ORY18222.1 - 0.33 10.1 0.7 0.69 9.1 0.7 1.5 1 0 0 1 1 1 0 Met-zincin COesterase PF00135.28 ORY18223.1 - 9.1e-84 282.1 0.0 1.1e-83 281.9 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 ORY18223.1 - 5.3e-06 26.4 0.4 2.4e-05 24.3 0.4 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 ORY18223.1 - 0.00012 21.6 0.0 0.00022 20.8 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 ORY18223.1 - 0.085 12.5 0.0 0.79 9.3 0.0 2.0 2 0 0 2 2 2 0 Putative esterase GFA PF04828.14 ORY18224.1 - 8.3e-05 22.9 1.7 8.3e-05 22.9 1.7 1.8 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme WSC PF01822.19 ORY18225.1 - 2.7e-21 75.5 18.7 3e-15 56.2 13.9 2.1 2 0 0 2 2 2 2 WSC domain PAN_2 PF08276.11 ORY18225.1 - 0.011 15.8 9.6 0.23 11.6 2.4 3.4 3 0 0 3 3 3 0 PAN-like domain Phage_lambda_P PF06992.11 ORY18225.1 - 0.089 12.5 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 Replication protein P MFS_1 PF07690.16 ORY18227.1 - 3.3e-19 69.1 42.5 4.2e-17 62.1 37.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY18227.1 - 4.2e-06 25.9 9.6 4.2e-06 25.9 9.6 3.0 1 1 0 2 2 2 1 Sugar (and other) transporter DUF4231 PF14015.6 ORY18227.1 - 0.62 10.6 7.2 3.5 8.2 0.3 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) CNH PF00780.22 ORY18229.1 - 3.5e-77 259.7 0.0 5.2e-77 259.2 0.0 1.2 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.20 ORY18229.1 - 3e-30 105.8 0.0 5.1e-30 105.1 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.6 ORY18229.1 - 1.3e-12 48.0 0.1 9.2e-11 42.0 0.0 2.9 2 1 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 ORY18229.1 - 0.0042 17.6 0.0 0.16 12.5 0.0 2.6 2 0 0 2 2 2 1 PH domain HET PF06985.11 ORY18230.1 - 7.8e-22 78.2 0.0 1.7e-21 77.1 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) AAA_16 PF13191.6 ORY18231.1 - 1.1e-05 25.9 0.0 2.7e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 ORY18231.1 - 3.2e-05 23.9 0.0 6.7e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_14 PF13173.6 ORY18231.1 - 0.011 15.7 0.0 0.069 13.2 0.0 2.3 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 ORY18231.1 - 0.015 15.8 0.0 0.068 13.6 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 ORY18231.1 - 0.016 15.5 0.0 0.044 14.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 ORY18231.1 - 0.035 14.5 0.0 0.08 13.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.6 ORY18231.1 - 0.077 12.6 0.0 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 ORY18231.1 - 0.16 11.8 0.0 0.33 10.8 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA PF00004.29 ORY18232.1 - 2.8e-17 63.4 0.0 7.5e-17 62.0 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 ORY18232.1 - 0.0014 19.0 0.4 0.021 15.1 0.1 2.5 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 ORY18232.1 - 0.04 13.7 0.0 0.081 12.7 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 ORY18232.1 - 0.068 13.6 1.5 1.2 9.5 0.1 2.4 1 1 1 2 2 2 0 AAA ATPase domain PhaP_Bmeg PF09602.10 ORY18232.1 - 0.1 12.5 1.5 3.7 7.5 0.3 2.5 2 0 0 2 2 2 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) AAA_17 PF13207.6 ORY18232.1 - 0.22 11.9 0.1 0.22 11.9 0.1 3.0 4 0 0 4 4 4 0 AAA domain AA_permease PF00324.21 ORY18233.1 - 1.2e-128 429.7 38.0 1.5e-128 429.5 38.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ORY18233.1 - 2.2e-34 119.1 41.4 2.7e-34 118.7 41.4 1.2 1 0 0 1 1 1 1 Amino acid permease DZR PF12773.7 ORY18234.1 - 0.0053 16.8 11.5 0.0053 16.8 11.5 3.3 2 1 1 3 3 3 2 Double zinc ribbon zinc_ribbon_2 PF13240.6 ORY18234.1 - 0.016 14.9 5.3 0.016 14.9 5.3 4.0 3 2 0 3 3 3 0 zinc-ribbon domain HscB_4_cys PF18256.1 ORY18234.1 - 0.13 12.1 0.1 0.13 12.1 0.1 4.8 4 1 1 5 5 5 0 Co-chaperone HscB tetracysteine metal binding motif A2L_zn_ribbon PF08792.10 ORY18234.1 - 0.62 9.8 0.2 0.62 9.8 0.2 5.0 6 0 0 6 6 6 0 A2L zinc ribbon domain Ribosomal_L32p PF01783.23 ORY18234.1 - 2.7 8.3 9.4 2.1 8.7 0.2 3.5 4 0 0 4 4 4 0 Ribosomal L32p protein family NRDD PF13597.6 ORY18234.1 - 8.4 5.0 7.6 7 5.3 1.2 2.1 1 1 1 2 2 2 0 Anaerobic ribonucleoside-triphosphate reductase zf_UBZ PF18439.1 ORY18234.1 - 10 5.8 10.6 1.9 8.2 0.2 3.9 3 1 1 4 4 4 0 Ubiquitin-Binding Zinc Finger MFS_1 PF07690.16 ORY18237.1 - 6.3e-49 166.8 52.0 5.6e-41 140.6 30.0 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY18237.1 - 2.7e-11 43.0 19.1 4.3e-11 42.4 19.1 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.7 ORY18237.1 - 0.0055 15.6 2.1 0.0055 15.6 2.1 2.5 2 1 0 2 2 2 1 MFS_1 like family LapA_dom PF06305.11 ORY18237.1 - 2.8 7.8 4.6 9.4 6.1 0.3 3.4 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain DUF2052 PF09747.9 ORY18238.1 - 1.8e-25 90.2 10.8 3.2e-24 86.2 10.8 2.1 1 1 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) Spermine_synth PF01564.17 ORY18239.1 - 3.1e-07 30.0 0.0 5.8e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Spermine/spermidine synthase domain HET PF06985.11 ORY18240.1 - 1.1e-28 100.4 0.1 2.1e-28 99.5 0.1 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HATPase_c_3 PF13589.6 ORY18241.1 - 0.0097 15.7 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF3883 PF13020.6 ORY18241.1 - 0.17 11.9 0.0 0.43 10.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3883) AAA PF00004.29 ORY18242.1 - 1.8e-15 57.5 0.0 4e-15 56.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 ORY18242.1 - 5e-05 23.8 0.4 0.00037 20.9 0.4 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 ORY18242.1 - 0.00041 20.6 1.6 0.0074 16.6 0.0 2.8 2 1 1 3 3 3 1 AAA domain AAA_5 PF07728.14 ORY18242.1 - 0.00076 19.5 0.0 0.0019 18.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) HTH_32 PF13565.6 ORY18242.1 - 0.0091 16.6 0.8 0.38 11.4 0.2 3.7 4 0 0 4 4 4 1 Homeodomain-like domain AAA_33 PF13671.6 ORY18242.1 - 0.046 13.9 0.0 0.15 12.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 ORY18242.1 - 0.062 13.0 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Zot PF05707.12 ORY18242.1 - 0.064 12.9 0.0 6.4 6.4 0.0 2.6 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) AAA_18 PF13238.6 ORY18242.1 - 0.07 13.7 0.1 0.49 10.9 0.0 2.6 3 0 0 3 3 3 0 AAA domain CPT PF07931.12 ORY18242.1 - 0.14 12.0 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein RuvB_N PF05496.12 ORY18242.1 - 0.17 11.6 0.0 0.38 10.5 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Hydin_ADK PF17213.3 ORY18242.1 - 0.27 11.5 1.8 0.53 10.5 0.1 2.3 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain AAA_11 PF13086.6 ORY18242.1 - 0.37 10.5 0.0 0.37 10.5 0.0 2.3 3 0 0 3 3 3 0 AAA domain DUF3376 PF11856.8 ORY18243.1 - 0.026 13.5 0.8 0.046 12.7 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3376) ApoLp-III PF07464.11 ORY18243.1 - 0.032 14.3 0.8 0.21 11.7 0.3 2.1 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) DUF3810 PF12725.7 ORY18243.1 - 0.066 12.5 0.3 20 4.4 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3810) CdvA PF18822.1 ORY18243.1 - 2.3 8.0 5.3 2.7 7.8 0.7 2.4 2 0 0 2 2 2 0 CdvA-like coiled-coil domain Glyco_hydro_17 PF00332.18 ORY18247.1 - 1.7e-10 41.0 2.1 5.8e-08 32.7 0.6 2.2 1 1 1 2 2 2 2 Glycosyl hydrolases family 17 SNARE PF05739.19 ORY18247.1 - 0.0021 18.0 0.1 0.004 17.1 0.1 1.4 1 0 0 1 1 1 1 SNARE domain UCR_Fe-S_N PF10399.9 ORY18247.1 - 0.018 14.4 0.0 0.43 10.0 0.0 2.6 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Rick_17kDa_Anti PF05433.15 ORY18247.1 - 0.021 14.7 1.1 0.021 14.7 1.1 2.8 3 0 0 3 3 3 0 Glycine zipper 2TM domain DUF5326 PF17260.2 ORY18247.1 - 0.025 14.7 2.3 0.043 14.0 2.3 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5326) ETRAMP PF09716.10 ORY18247.1 - 0.11 12.6 1.4 0.13 12.3 0.0 1.9 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Trep_Strep PF09605.10 ORY18247.1 - 0.16 11.9 0.2 0.27 11.2 0.2 1.3 1 0 0 1 1 1 0 Hypothetical bacterial integral membrane protein (Trep_Strep) DUF4179 PF13786.6 ORY18247.1 - 0.19 12.2 0.4 1.2 9.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4179) Wzz PF02706.15 ORY18247.1 - 1.9 8.9 3.8 6.5 7.1 1.4 2.3 2 0 0 2 2 2 0 Chain length determinant protein HRXXH PF13933.6 ORY18250.1 - 4.3e-72 242.6 0.4 6.4e-72 242.1 0.4 1.2 1 0 0 1 1 1 1 Putative peptidase family Aspzincin_M35 PF14521.6 ORY18250.1 - 1.7e-05 25.4 0.9 4.4e-05 24.1 0.0 2.0 2 0 0 2 2 2 1 Lysine-specific metallo-endopeptidase Zip PF02535.22 ORY18251.1 - 1.1e-33 116.9 25.6 1.1e-33 116.9 25.6 3.0 2 1 0 2 2 2 1 ZIP Zinc transporter UNC-50 PF05216.13 ORY18251.1 - 3.4 7.2 9.4 0.9 9.0 2.2 2.4 2 0 0 2 2 2 0 UNC-50 family FAD_binding_3 PF01494.19 ORY18252.1 - 3.7e-08 33.0 0.1 3.3e-07 29.9 0.1 1.9 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 ORY18252.1 - 0.0097 15.2 0.0 0.017 14.4 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase His_Phos_2 PF00328.22 ORY18253.1 - 4.6e-40 138.1 0.0 1.2e-39 136.8 0.0 1.6 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Transp_cyt_pur PF02133.15 ORY18254.1 - 1.3e-21 76.9 36.0 1.3e-21 76.9 36.0 1.7 1 1 1 2 2 2 1 Permease for cytosine/purines, uracil, thiamine, allantoin Beta_helix PF13229.6 ORY18255.1 - 7e-12 45.5 22.7 2.2e-06 27.6 1.9 2.6 1 1 1 2 2 2 2 Right handed beta helix region NosD PF05048.13 ORY18255.1 - 1.9e-08 33.9 13.9 0.0018 17.6 0.0 2.8 2 1 0 2 2 2 2 Periplasmic copper-binding protein (NosD) Molybdop_Fe4S4 PF04879.16 ORY18255.1 - 0.08 13.0 2.5 9.4 6.3 0.4 2.6 2 0 0 2 2 2 0 Molybdopterin oxidoreductase Fe4S4 domain ThuA PF06283.11 ORY18256.1 - 3.9e-62 210.2 0.3 4.4e-62 210.0 0.3 1.0 1 0 0 1 1 1 1 Trehalose utilisation zf-HC5HC2H_2 PF13832.6 ORY18257.1 - 0.013 15.7 6.1 0.3 11.2 0.5 3.0 2 1 0 2 2 2 0 PHD-zinc-finger like domain FANCL_C PF11793.8 ORY18257.1 - 0.68 10.1 5.0 0.51 10.6 2.0 2.3 2 0 0 2 2 2 0 FANCL C-terminal domain PQ-loop PF04193.14 ORY18258.1 - 1.6e-21 75.8 9.8 6e-20 70.8 1.7 2.8 2 1 0 2 2 2 2 PQ loop repeat MtN3_slv PF03083.16 ORY18258.1 - 0.0073 16.3 0.9 0.0073 16.3 0.9 2.3 3 0 0 3 3 3 1 Sugar efflux transporter for intercellular exchange Alpha-amylase PF00128.24 ORY18260.1 - 1.2e-19 71.1 0.1 4.1e-19 69.3 0.1 1.9 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.11 ORY18260.1 - 5.4e-15 55.8 0.0 9.6e-15 54.9 0.0 1.4 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 ORY18260.1 - 2.6e-07 30.3 0.0 4.9e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 ORY18260.1 - 0.01 15.8 0.0 0.024 14.7 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase Family 4 Big_5 PF13205.6 ORY18260.1 - 0.13 13.0 0.0 0.34 11.6 0.0 1.6 1 0 0 1 1 1 0 Bacterial Ig-like domain DUF5001 PF16392.5 ORY18260.1 - 0.22 11.4 0.2 19 5.2 0.0 2.7 2 0 0 2 2 2 0 Ig-like domain HET PF06985.11 ORY18262.1 - 1.9e-34 119.1 3.5 2.2e-34 118.9 3.5 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) zf-C2H2_4 PF13894.6 ORY18263.1 - 1.4e-13 50.4 29.8 0.00056 20.5 0.7 6.8 6 0 0 6 6 6 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORY18263.1 - 3.7e-12 46.1 25.3 8.3e-05 22.8 0.7 6.4 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2 PF00096.26 ORY18263.1 - 3.5e-09 36.6 33.5 0.0029 18.0 0.8 6.6 6 0 0 6 6 6 4 Zinc finger, C2H2 type zf-met PF12874.7 ORY18263.1 - 7.9e-09 35.6 9.4 0.025 15.0 0.1 5.9 6 0 0 6 6 6 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 ORY18263.1 - 1e-07 32.1 12.2 0.015 15.6 0.5 4.7 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding Zn-C2H2_12 PF18112.1 ORY18263.1 - 0.014 15.8 0.8 0.9 10.1 0.0 3.0 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain zf-C2H2_11 PF16622.5 ORY18263.1 - 0.27 11.0 20.1 0.5 10.2 0.8 5.0 5 0 0 5 5 5 0 zinc-finger C2H2-type Ephrin_rec_like PF07699.13 ORY18263.1 - 1.3 8.9 8.0 8.9 6.2 0.2 4.0 4 0 0 4 4 4 0 Putative ephrin-receptor like zf-C2H2_6 PF13912.6 ORY18263.1 - 1.7 8.8 17.3 0.2 11.7 0.6 5.2 5 0 0 5 5 5 0 C2H2-type zinc finger zf-TRAF PF02176.18 ORY18263.1 - 3.4 8.4 17.4 1.8 9.3 0.3 3.8 4 0 0 4 4 4 0 TRAF-type zinc finger zinc-ribbons_6 PF07191.12 ORY18263.1 - 3.7 7.6 8.0 9.2 6.3 0.1 3.7 3 1 0 3 3 3 0 zinc-ribbons zf-C2H2_3rep PF18868.1 ORY18263.1 - 4.4 8.0 10.4 8.2 7.1 0.1 3.5 2 2 2 4 4 4 0 Zinc finger C2H2-type, 3 repeats DUF2225 PF09986.9 ORY18263.1 - 7.4 6.2 6.8 0.67 9.6 1.4 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) CFEM PF05730.11 ORY18265.1 - 4.8e-13 49.0 9.5 9.7e-13 48.0 9.5 1.5 1 0 0 1 1 1 1 CFEM domain BT1 PF03092.16 ORY18285.1 - 0.5 8.5 1.2 0.67 8.1 1.2 1.1 1 0 0 1 1 1 0 BT1 family MFS_1 PF07690.16 ORY18286.1 - 2.5e-25 89.1 40.6 6.7e-23 81.2 18.8 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily ABC_tran PF00005.27 ORY18288.1 - 5.3e-15 56.1 0.0 4.5e-10 40.2 0.0 2.9 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 ORY18288.1 - 1.8e-05 24.7 0.0 0.036 13.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 ORY18288.1 - 0.0016 18.7 0.0 0.0064 16.7 0.0 1.9 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 ORY18288.1 - 0.017 15.7 0.6 0.03 14.8 0.6 1.3 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 ORY18288.1 - 0.1 12.3 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 ORY18288.1 - 0.1 12.8 0.0 0.35 11.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain Thioredoxin PF00085.20 ORY18290.1 - 8.5e-28 96.4 0.1 1e-27 96.1 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_9 PF14595.6 ORY18290.1 - 1.7e-05 24.6 0.0 2.1e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 ORY18290.1 - 2.6e-05 24.6 0.4 0.00023 21.6 0.4 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 ORY18290.1 - 0.00035 20.8 0.0 0.0062 16.8 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin-like OST3_OST6 PF04756.13 ORY18290.1 - 0.00059 19.3 0.0 0.0007 19.0 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Redoxin PF08534.10 ORY18290.1 - 0.0038 16.9 0.3 0.24 11.1 0.2 2.1 1 1 1 2 2 2 1 Redoxin Phosducin PF02114.16 ORY18290.1 - 0.018 14.0 0.0 0.02 13.8 0.0 1.1 1 0 0 1 1 1 0 Phosducin TraF PF13728.6 ORY18290.1 - 0.069 13.0 0.0 0.079 12.8 0.0 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein HyaE PF07449.11 ORY18290.1 - 0.11 12.5 0.0 0.14 12.1 0.0 1.4 1 1 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Nuf2 PF03800.14 ORY18293.1 - 7.9e-43 145.9 0.3 1.9e-42 144.7 0.3 1.7 1 0 0 1 1 1 1 Nuf2 family DHR10 PF18595.1 ORY18293.1 - 4.7e-32 110.5 19.4 4.7e-32 110.5 19.4 3.5 3 1 0 3 3 3 1 Designed helical repeat protein 10 domain SlyX PF04102.12 ORY18293.1 - 0.33 11.6 0.1 0.33 11.6 0.1 5.6 3 2 1 4 4 4 0 SlyX Abhydrolase_6 PF12697.7 ORY18294.1 - 4.3e-15 56.9 3.1 5.9e-15 56.5 3.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORY18294.1 - 5.7e-10 38.9 0.1 4.3e-09 36.0 0.1 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ORY18294.1 - 1e-05 25.3 3.4 0.00016 21.4 3.4 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF1749 PF08538.10 ORY18294.1 - 0.014 14.5 0.0 0.24 10.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1749) Glyco_hydro_61 PF03443.14 ORY18295.1 - 7e-53 179.6 0.0 1.6e-52 178.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 SesA PF17107.5 ORY18296.1 - 0.00043 20.5 0.8 0.0015 18.7 0.1 2.2 2 0 0 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases DUF1664 PF07889.12 ORY18296.1 - 0.0029 17.6 0.0 37 4.4 0.0 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) ATP-synt_D PF01813.17 ORY18296.1 - 0.027 14.3 0.1 0.078 12.8 0.1 1.8 1 0 0 1 1 1 0 ATP synthase subunit D Helo_like_N PF17111.5 ORY18296.1 - 0.068 12.5 0.6 0.65 9.3 0.1 2.5 3 0 0 3 3 3 0 Fungal N-terminal domain of STAND proteins Rhabdo_ncap_2 PF03216.13 ORY18296.1 - 0.069 12.6 0.1 0.13 11.7 0.1 1.4 1 0 0 1 1 1 0 Rhabdovirus nucleoprotein DHR10 PF18595.1 ORY18296.1 - 3.3 7.8 7.4 40 4.3 0.0 3.9 4 1 0 4 4 4 0 Designed helical repeat protein 10 domain HrcA_DNA-bdg PF03444.15 ORY18300.1 - 0.033 13.8 0.0 0.077 12.7 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding Rib_5-P_isom_A PF06026.14 ORY18301.1 - 1.5e-41 141.9 0.0 2.9e-41 140.9 0.0 1.4 1 1 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) Sugar-bind PF04198.13 ORY18301.1 - 0.026 13.7 0.0 0.039 13.1 0.0 1.2 1 0 0 1 1 1 0 Putative sugar-binding domain DeoRC PF00455.22 ORY18301.1 - 0.026 14.4 0.2 2.8 7.9 0.2 2.3 1 1 0 1 1 1 0 DeoR C terminal sensor domain ThiF PF00899.21 ORY18302.1 - 6.4e-16 58.4 0.0 1.1e-15 57.7 0.0 1.4 1 1 0 1 1 1 1 ThiF family Nup84_Nup100 PF04121.13 ORY18303.1 - 9.3e-138 460.4 1.5 1.1e-137 460.1 1.5 1.1 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 KIP1 PF07765.12 ORY18303.1 - 0.39 10.9 3.3 0.9 9.7 0.1 3.0 2 0 0 2 2 2 0 KIP1-like protein Sec16 PF12932.7 ORY18303.1 - 0.41 11.2 1.7 9 6.9 0.3 2.6 2 0 0 2 2 2 0 Vesicle coat trafficking protein Sec16 mid-region MTCP1 PF08991.10 ORY18304.1 - 6.9e-29 99.9 11.6 7.9e-29 99.7 11.6 1.0 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type CHCH PF06747.13 ORY18304.1 - 0.033 14.3 8.5 0.033 14.3 8.5 1.9 2 0 0 2 2 2 0 CHCH domain Cmc1 PF08583.10 ORY18304.1 - 0.4 10.7 9.3 0.27 11.3 6.3 2.0 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Rad60-SLD PF11976.8 ORY18305.1 - 2.2e-20 72.3 0.7 2.7e-20 72.0 0.7 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 ORY18305.1 - 1.2e-11 44.2 0.2 1.4e-11 44.0 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin family Totivirus_coat PF05518.11 ORY18306.1 - 0.99 7.4 3.1 1.2 7.2 3.1 1.1 1 0 0 1 1 1 0 Totivirus coat protein ADH_zinc_N PF00107.26 ORY18307.1 - 1e-27 96.6 0.1 1.8e-27 95.9 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ORY18307.1 - 6.5e-17 62.8 0.1 1.1e-16 62.1 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ORY18307.1 - 4.1e-08 33.1 0.0 8e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 ORY18307.1 - 0.002 18.0 0.0 0.0048 16.8 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase adh_short PF00106.25 ORY18307.1 - 0.0024 17.3 2.1 0.0051 16.3 1.0 2.1 2 1 0 2 2 2 1 short chain dehydrogenase RELT PF12606.8 ORY18307.1 - 0.085 11.9 0.0 0.15 11.1 0.0 1.4 1 0 0 1 1 1 0 Tumour necrosis factor receptor superfamily member 19 Pex2_Pex12 PF04757.14 ORY18310.1 - 1.1e-53 182.1 2.6 1.4e-53 181.8 2.6 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.6 ORY18310.1 - 0.00011 22.3 0.7 0.00017 21.7 0.7 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 ORY18310.1 - 0.0034 17.2 0.4 0.0053 16.6 0.4 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORY18310.1 - 0.0039 17.2 1.3 0.0068 16.4 1.3 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 ORY18310.1 - 0.0044 16.9 0.3 0.0063 16.3 0.3 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 ORY18310.1 - 0.0055 16.5 0.5 0.0091 15.8 0.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORY18310.1 - 0.05 14.0 0.7 0.081 13.3 0.7 1.3 1 0 0 1 1 1 0 Ring finger domain zf-FPG_IleRS PF06827.14 ORY18310.1 - 0.26 11.2 1.1 0.53 10.2 1.1 1.6 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS Sec7 PF01369.20 ORY18311.1 - 2e-63 213.4 0.0 3.1e-63 212.8 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 ORY18311.1 - 4.4e-21 75.4 0.3 4.9e-19 68.8 0.0 3.4 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal TAF4 PF05236.14 ORY18311.1 - 0.4 10.4 4.3 1.5 8.5 0.1 2.4 2 0 0 2 2 2 0 Transcription initiation factor TFIID component TAF4 family Glyco_hydro_72 PF03198.14 ORY18312.1 - 3e-113 378.3 0.0 3.6e-113 378.0 0.0 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Totivirus_coat PF05518.11 ORY18314.1 - 4.7 5.1 7.9 5.7 4.9 7.9 1.0 1 0 0 1 1 1 0 Totivirus coat protein PIF1 PF05970.14 ORY18315.1 - 0.044 13.0 0.0 0.045 12.9 0.0 1.0 1 0 0 1 1 1 0 PIF1-like helicase Ammonium_transp PF00909.21 ORY18317.1 - 4.3e-112 374.7 26.9 5.1e-112 374.5 26.9 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family DUF3482 PF11981.8 ORY18317.1 - 1.1 8.6 4.0 1.8 7.9 4.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) CdiI_4 PF18624.1 ORY18318.1 - 0.17 12.4 0.0 0.5 10.9 0.0 1.7 1 0 0 1 1 1 0 CDI immunity protein Asp PF00026.23 ORY18322.1 - 2.5e-10 40.3 0.0 3.6e-10 39.8 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease DUF2568 PF10823.8 ORY18322.1 - 0.039 14.2 0.0 0.079 13.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2568) EHN PF06441.12 ORY18323.1 - 1.3e-26 93.1 0.6 1.1e-24 86.9 0.0 2.2 2 0 0 2 2 2 2 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 ORY18323.1 - 5.2e-09 36.1 0.1 7.3e-09 35.6 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORY18323.1 - 0.018 15.7 3.9 0.08 13.5 3.9 2.0 1 1 0 1 1 1 0 Alpha/beta hydrolase family FAD_binding_4 PF01565.23 ORY18324.1 - 7.6e-24 84.0 1.3 1.4e-23 83.2 1.3 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 ORY18324.1 - 1.7e-08 34.4 0.1 3.5e-08 33.4 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like MFS_1 PF07690.16 ORY18325.1 - 4.1e-49 167.4 39.0 3.1e-48 164.5 40.4 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 ORY18325.1 - 8.2e-16 57.5 21.3 1.9e-15 56.3 21.3 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 ORY18325.1 - 1e-11 44.4 10.3 1e-11 44.4 10.3 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter Phage_sheath_1 PF04984.14 ORY18326.1 - 0.063 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Phage tail sheath protein subtilisin-like domain Tropomyosin_1 PF12718.7 ORY18328.1 - 7.7e-06 26.1 12.0 5.4e-05 23.4 2.5 2.5 2 0 0 2 2 2 1 Tropomyosin like TPR_MLP1_2 PF07926.12 ORY18328.1 - 1.9e-05 24.7 6.8 1.9e-05 24.7 6.8 2.5 2 0 0 2 2 2 1 TPR/MLP1/MLP2-like protein GAS PF13851.6 ORY18328.1 - 7.1e-05 22.2 6.6 7.1e-05 22.2 6.6 2.2 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding DUF4201 PF13870.6 ORY18328.1 - 0.00047 20.0 7.7 0.00047 20.0 7.7 2.5 1 1 1 2 2 2 1 Domain of unknown function (DUF4201) TMF_DNA_bd PF12329.8 ORY18328.1 - 0.0016 18.4 23.2 0.24 11.4 7.9 3.6 1 1 2 3 3 3 2 TATA element modulatory factor 1 DNA binding DUF4407 PF14362.6 ORY18328.1 - 0.0025 17.2 15.0 0.015 14.7 14.5 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF4407) Lebercilin PF15619.6 ORY18328.1 - 0.0025 17.5 21.4 0.066 12.9 9.7 2.4 1 1 1 2 2 2 2 Ciliary protein causing Leber congenital amaurosis disease EzrA PF06160.12 ORY18328.1 - 0.0048 15.1 11.9 0.055 11.7 13.1 2.0 2 1 0 2 2 2 1 Septation ring formation regulator, EzrA CCDC144C PF14915.6 ORY18328.1 - 0.005 16.0 6.7 0.005 16.0 6.7 2.2 2 0 0 2 2 2 1 CCDC144C protein coiled-coil region MAD PF05557.13 ORY18328.1 - 0.0061 15.0 14.2 0.0089 14.4 14.2 1.1 1 0 0 1 1 1 1 Mitotic checkpoint protein FPP PF05911.11 ORY18328.1 - 0.0084 14.4 12.0 0.011 13.9 12.0 1.1 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil Tropomyosin PF00261.20 ORY18328.1 - 0.0086 15.5 16.5 0.015 14.6 16.2 1.6 1 1 0 1 1 1 1 Tropomyosin UPF0242 PF06785.11 ORY18328.1 - 0.022 14.9 17.6 0.019 15.1 8.1 2.4 1 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus HrpB7 PF09486.10 ORY18328.1 - 0.022 15.1 1.7 0.022 15.1 1.7 2.8 3 0 0 3 3 2 0 Bacterial type III secretion protein (HrpB7) PKcGMP_CC PF16808.5 ORY18328.1 - 0.023 14.5 8.7 0.55 10.1 1.2 3.5 3 0 0 3 3 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DivIC PF04977.15 ORY18328.1 - 0.026 14.3 13.9 0.055 13.2 0.3 4.0 1 1 3 4 4 4 0 Septum formation initiator Tup_N PF08581.10 ORY18328.1 - 0.041 14.2 0.3 0.041 14.2 0.3 3.0 1 1 2 3 3 3 0 Tup N-terminal AAA_13 PF13166.6 ORY18328.1 - 0.052 12.2 14.2 0.77 8.3 14.2 2.0 1 1 0 1 1 1 0 AAA domain PspA_IM30 PF04012.12 ORY18328.1 - 0.054 13.1 16.2 1.2 8.7 0.9 2.9 2 1 0 2 2 2 0 PspA/IM30 family CP12 PF02672.15 ORY18328.1 - 0.054 14.2 1.9 17 6.2 0.7 3.6 3 1 0 3 3 3 0 CP12 domain Transcrip_act PF04949.13 ORY18328.1 - 0.058 13.3 13.3 0.37 10.7 6.3 2.5 1 1 1 2 2 2 0 Transcriptional activator DUF1202 PF06717.11 ORY18328.1 - 0.059 12.8 1.5 0.12 11.8 1.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1202) SlyX PF04102.12 ORY18328.1 - 0.11 13.2 16.6 0.53 10.9 0.1 4.2 3 1 1 4 4 3 0 SlyX DUF3584 PF12128.8 ORY18328.1 - 0.13 9.7 13.7 0.34 8.4 13.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) OmpH PF03938.14 ORY18328.1 - 0.15 12.4 19.1 1.3 9.3 4.6 2.5 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Spc7 PF08317.11 ORY18328.1 - 0.17 10.7 20.0 3.1 6.6 20.1 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF948 PF06103.11 ORY18328.1 - 0.18 12.1 4.2 0.75 10.1 0.3 3.2 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Exonuc_VII_L PF02601.15 ORY18328.1 - 0.19 11.3 11.3 2 7.9 11.3 2.1 1 1 0 1 1 1 0 Exonuclease VII, large subunit Filament PF00038.21 ORY18328.1 - 0.19 11.3 14.7 0.07 12.7 9.6 2.3 1 1 2 3 3 3 0 Intermediate filament protein APG6_N PF17675.1 ORY18328.1 - 0.22 12.1 16.5 0.061 13.8 12.6 2.0 1 1 0 1 1 1 0 Apg6 coiled-coil region Baculo_PEP_C PF04513.12 ORY18328.1 - 0.28 11.2 4.0 1.6 8.7 2.4 2.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4795 PF16043.5 ORY18328.1 - 0.3 10.7 12.7 0.6 9.7 12.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) She9_MDM33 PF05546.11 ORY18328.1 - 0.37 10.6 6.9 4.7 7.0 0.4 2.5 1 1 1 2 2 2 0 She9 / Mdm33 family YlqD PF11068.8 ORY18328.1 - 0.5 10.7 15.9 1.4 9.3 3.0 2.4 1 1 1 2 2 2 0 YlqD protein TMF_TATA_bd PF12325.8 ORY18328.1 - 0.56 10.4 17.1 1.1 9.6 6.1 3.3 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding Laminin_II PF06009.12 ORY18328.1 - 0.65 10.0 10.5 6 6.9 1.1 3.3 1 1 2 3 3 3 0 Laminin Domain II DUF4763 PF15960.5 ORY18328.1 - 0.81 8.9 12.1 12 5.1 0.1 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4763) ADIP PF11559.8 ORY18328.1 - 0.82 9.7 17.2 0.081 13.0 6.7 2.7 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding FAM76 PF16046.5 ORY18328.1 - 0.97 8.7 17.0 0.044 13.1 4.8 2.2 1 1 1 2 2 2 0 FAM76 protein DUF16 PF01519.16 ORY18328.1 - 1 9.9 15.3 5.4 7.6 4.3 2.6 1 1 1 2 2 2 0 Protein of unknown function DUF16 DASH_Spc34 PF08657.10 ORY18328.1 - 1.1 9.0 9.2 5.9 6.6 9.2 2.1 1 1 0 1 1 1 0 DASH complex subunit Spc34 PI3K_P85_iSH2 PF16454.5 ORY18328.1 - 1.2 8.7 11.4 0.89 9.1 6.8 2.4 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain kleA_kleC PF17383.2 ORY18328.1 - 1.3 9.4 5.8 0.83 10.0 1.1 2.7 2 1 0 2 2 2 0 Uncharacterized KorC regulated protein A Golgin_A5 PF09787.9 ORY18328.1 - 1.3 8.4 16.1 3.4 7.1 16.0 1.6 1 1 0 1 1 1 0 Golgin subfamily A member 5 CENP-F_leu_zip PF10473.9 ORY18328.1 - 1.3 9.0 20.0 1 9.3 13.4 2.7 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF641 PF04859.12 ORY18328.1 - 1.5 9.1 14.2 11 6.3 0.3 3.6 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) Fez1 PF06818.15 ORY18328.1 - 1.7 9.0 18.7 4.9 7.6 8.9 2.6 1 1 1 2 2 2 0 Fez1 DUF4200 PF13863.6 ORY18328.1 - 2.2 8.7 23.2 0.81 10.1 11.8 3.1 2 1 1 3 3 2 0 Domain of unknown function (DUF4200) IFT57 PF10498.9 ORY18328.1 - 2.7 6.9 13.2 0.74 8.7 7.4 2.1 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 Phage_GP20 PF06810.11 ORY18328.1 - 2.8 7.7 16.0 0.11 12.3 5.6 2.9 1 1 1 2 2 2 0 Phage minor structural protein GP20 Mod_r PF07200.13 ORY18328.1 - 3.1 7.9 13.1 30 4.7 13.1 2.3 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein TolA_bind_tri PF16331.5 ORY18328.1 - 3.3 7.9 13.3 0.91 9.6 0.2 3.8 2 2 2 4 4 4 0 TolA binding protein trimerisation Atg14 PF10186.9 ORY18328.1 - 3.5 6.6 18.7 2.3 7.2 10.4 2.2 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF812 PF05667.11 ORY18328.1 - 3.9 6.2 18.4 6.6 5.5 17.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF812) Fib_alpha PF08702.10 ORY18328.1 - 4.7 7.4 11.2 4 7.6 2.3 2.6 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family NPV_P10 PF05531.12 ORY18328.1 - 5.8 7.5 7.8 1e+02 3.5 0.3 3.7 1 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein KxDL PF10241.9 ORY18328.1 - 6.6 7.1 7.3 3.4 8.0 0.6 3.2 1 1 1 3 3 2 0 Uncharacterized conserved protein Sec2p PF06428.11 ORY18328.1 - 6.7 6.7 15.3 0.33 10.9 4.7 3.0 2 1 0 3 3 2 0 GDP/GTP exchange factor Sec2p ING PF12998.7 ORY18328.1 - 6.9 7.3 10.0 11 6.7 1.7 2.6 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding Jnk-SapK_ap_N PF09744.9 ORY18328.1 - 8.9 6.5 17.2 16 5.7 8.7 2.7 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Csm1_N PF18504.1 ORY18328.1 - 9.8 6.6 18.8 0.51 10.7 4.1 3.7 2 1 1 3 3 3 0 Csm1 N-terminal domain Ank_2 PF12796.7 ORY18330.1 - 2.7e-15 56.7 0.0 3.2e-15 56.5 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 ORY18330.1 - 6.8e-12 45.3 0.0 0.0017 18.7 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 ORY18330.1 - 1.8e-11 44.4 0.0 1e-06 29.2 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY18330.1 - 1.9e-10 40.1 0.0 0.016 15.7 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 ORY18330.1 - 2.5e-05 24.5 0.0 0.18 12.2 0.0 2.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) PNP_UDP_1 PF01048.20 ORY18331.1 - 4.2e-14 52.4 0.3 7.6e-14 51.5 0.3 1.4 1 0 0 1 1 1 1 Phosphorylase superfamily zf-met PF12874.7 ORY18331.1 - 2.5e-08 34.0 16.0 0.1 13.1 0.2 4.7 4 0 0 4 4 4 4 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 ORY18331.1 - 4.9e-07 30.0 20.3 0.37 11.1 0.2 5.1 2 1 3 5 5 5 4 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 ORY18331.1 - 6.2e-07 29.5 15.1 0.66 10.3 0.1 4.5 4 0 0 4 4 4 4 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 ORY18331.1 - 1e-05 25.7 24.0 0.072 13.6 0.3 5.0 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY18331.1 - 0.11 13.4 10.4 17 6.6 0.1 4.7 4 0 0 4 4 4 0 C2H2-type zinc finger HNH_5 PF14279.6 ORY18331.1 - 0.14 12.0 11.2 13 5.7 0.1 3.7 1 1 1 3 3 3 0 HNH endonuclease DUF4428 PF14471.6 ORY18331.1 - 0.84 9.6 10.3 21 5.1 0.2 4.4 3 1 1 4 4 4 0 Domain of unknown function (DUF4428) GFA PF04828.14 ORY18331.1 - 2.6 8.4 13.6 4.6 7.6 0.2 4.3 2 1 2 4 4 4 0 Glutathione-dependent formaldehyde-activating enzyme zf_UBZ PF18439.1 ORY18331.1 - 7.5 6.2 11.2 6.6 6.4 0.0 4.4 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger CorA PF01544.18 ORY18334.1 - 8.3e-05 22.0 4.9 0.00018 20.9 4.9 1.6 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Exo70 PF03081.15 ORY18334.1 - 0.0014 17.8 0.1 0.002 17.2 0.1 1.1 1 0 0 1 1 1 1 Exo70 exocyst complex subunit Peptidase_M74 PF03411.13 ORY18334.1 - 0.11 12.0 0.2 0.17 11.4 0.2 1.2 1 0 0 1 1 1 0 Penicillin-insensitive murein endopeptidase TPR_10 PF13374.6 ORY18336.1 - 5.4e-151 487.1 8.3 8.1e-14 51.0 0.1 11.6 11 0 0 11 11 11 11 Tetratricopeptide repeat TPR_12 PF13424.6 ORY18336.1 - 1.5e-134 438.5 23.9 4.2e-17 62.2 0.0 11.2 1 1 10 11 11 11 11 Tetratricopeptide repeat TPR_7 PF13176.6 ORY18336.1 - 3.6e-55 180.0 7.3 0.00018 21.3 0.0 12.0 11 0 0 11 11 11 10 Tetratricopeptide repeat TPR_2 PF07719.17 ORY18336.1 - 6.9e-32 107.0 9.7 0.013 15.5 0.0 12.5 12 0 0 12 12 11 8 Tetratricopeptide repeat TPR_1 PF00515.28 ORY18336.1 - 1.9e-26 90.7 8.8 0.085 12.7 0.0 11.9 12 0 0 12 12 11 7 Tetratricopeptide repeat TPR_19 PF14559.6 ORY18336.1 - 2.1e-26 92.2 0.0 0.032 14.7 0.0 11.2 1 1 10 11 11 11 5 Tetratricopeptide repeat TPR_8 PF13181.6 ORY18336.1 - 5.7e-23 79.2 12.3 0.11 12.8 0.0 11.5 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_4 PF07721.14 ORY18336.1 - 2.7e-21 73.9 0.0 9.6 7.2 0.0 11.3 11 0 0 11 11 11 0 Tetratricopeptide repeat TPR_MalT PF17874.1 ORY18336.1 - 3.3e-20 72.7 21.6 2.8e-09 36.8 0.7 3.8 1 1 2 4 4 4 3 MalT-like TPR region TPR_17 PF13431.6 ORY18336.1 - 4.1e-20 70.6 14.5 0.65 10.5 0.0 10.7 11 0 0 11 11 10 6 Tetratricopeptide repeat TPR_16 PF13432.6 ORY18336.1 - 3e-19 69.4 6.0 0.31 11.7 0.0 12.0 10 3 3 13 13 11 3 Tetratricopeptide repeat TPR_6 PF13174.6 ORY18336.1 - 3.1e-11 43.1 18.0 1.1 10.0 0.0 11.2 12 0 0 12 12 9 3 Tetratricopeptide repeat TPR_14 PF13428.6 ORY18336.1 - 4.6e-10 39.5 15.2 22 6.2 0.0 11.4 11 1 1 12 12 10 0 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY18336.1 - 4.2e-08 33.3 2.8 5.3 7.3 0.0 8.4 2 1 7 9 9 8 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.6 ORY18336.1 - 5.1e-08 33.1 4.7 23 5.4 0.0 8.7 4 1 4 9 9 9 0 Tetratricopeptide repeat AAA_16 PF13191.6 ORY18336.1 - 8.3e-07 29.5 1.1 2.6e-06 27.9 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain PPR PF01535.20 ORY18336.1 - 3.8e-06 26.8 11.4 28 5.2 0.0 9.2 11 0 0 11 11 9 0 PPR repeat RPN6_N PF18055.1 ORY18336.1 - 8.8e-06 26.1 10.5 0.34 11.3 0.0 6.5 3 1 5 8 8 8 1 26S proteasome regulatory subunit RPN6 N-terminal domain DUF2664 PF10867.8 ORY18336.1 - 8.4e-05 22.9 6.2 4.1 7.9 0.0 7.3 10 0 0 10 10 7 1 Protein of unknown function (DUF2664) TPR_3 PF07720.12 ORY18336.1 - 0.00013 21.8 0.0 25 5.0 0.0 6.8 9 0 0 9 9 7 0 Tetratricopeptide repeat IstB_IS21 PF01695.17 ORY18336.1 - 0.00035 20.4 0.0 0.00079 19.2 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein ATPase_2 PF01637.18 ORY18336.1 - 0.0019 18.1 0.0 0.0038 17.2 0.0 1.6 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea CutA1 PF03091.15 ORY18336.1 - 0.0033 17.3 21.9 10 6.1 0.2 8.4 1 1 5 9 9 9 0 CutA1 divalent ion tolerance protein HET PF06985.11 ORY18336.1 - 0.0037 17.6 4.6 0.7 10.2 0.0 4.1 3 1 0 4 4 3 1 Heterokaryon incompatibility protein (HET) BRX_assoc PF16627.5 ORY18336.1 - 0.011 15.9 2.1 3e+02 1.6 0.0 6.1 6 0 0 6 6 6 0 Unstructured region between BRX_N and BRX domain AAA_22 PF13401.6 ORY18336.1 - 0.017 15.4 0.1 0.11 12.8 0.0 2.4 2 0 0 2 2 1 0 AAA domain PhoH PF02562.16 ORY18336.1 - 0.043 13.3 0.1 0.085 12.3 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_18 PF13238.6 ORY18336.1 - 0.11 13.1 0.0 0.43 11.1 0.0 2.1 1 0 0 1 1 1 0 AAA domain KIX_2 PF16987.5 ORY18336.1 - 0.13 12.2 2.4 69 3.5 0.0 5.2 3 2 4 7 7 6 0 KIX domain PMAIP1 PF15150.6 ORY18336.1 - 0.19 11.6 0.0 3.1 7.7 0.0 2.6 2 0 0 2 2 2 0 Phorbol-12-myristate-13-acetate-induced zf-Mss51 PF13824.6 ORY18336.1 - 0.24 11.5 1.8 1.4e+02 2.7 0.0 5.3 6 0 0 6 6 6 0 Zinc-finger of mitochondrial splicing suppressor 51 AAA_24 PF13479.6 ORY18336.1 - 0.37 10.5 2.3 0.72 9.5 0.0 2.8 4 0 0 4 4 2 0 AAA domain DUF4440 PF14534.6 ORY18336.1 - 0.58 10.6 7.6 1.4e+02 2.9 0.0 5.3 4 2 1 6 6 5 0 Domain of unknown function (DUF4440) DUF1897 PF09005.10 ORY18336.1 - 0.59 9.7 16.8 26 4.4 0.1 6.8 8 0 0 8 8 8 0 Domain of unknown function (DUF1897) DUF3157 PF11355.8 ORY18336.1 - 1.7 8.2 5.6 2.7 7.6 0.3 3.3 2 1 3 5 5 5 0 Protein of unknown function (DUF3157) RNR_Alpha PF17975.1 ORY18336.1 - 5 7.7 28.0 1.5 9.4 0.2 5.9 2 1 5 7 7 7 0 Ribonucleotide reductase alpha domain MazG PF03819.17 ORY18336.1 - 7.2 6.9 13.2 30 4.9 0.1 5.9 2 1 3 7 7 6 0 MazG nucleotide pyrophosphohydrolase domain Isochorismatase PF00857.20 ORY18337.1 - 1.3e-20 74.3 0.0 1.7e-20 73.9 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family Pkinase PF00069.25 ORY18338.1 - 8.2e-13 48.3 0.0 2.1e-08 33.9 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_fungal PF17667.1 ORY18338.1 - 0.0028 16.5 0.1 0.004 16.0 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_Tyr PF07714.17 ORY18338.1 - 0.16 11.2 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase MFS_1 PF07690.16 ORY18339.1 - 9.8e-20 70.8 46.1 5.2e-17 61.8 28.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TauD PF02668.16 ORY18340.1 - 8.9e-31 107.7 0.5 2e-30 106.5 0.5 1.5 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family HET PF06985.11 ORY18343.1 - 8.6e-32 110.5 2.6 1.8e-31 109.5 2.6 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) TPR_1 PF00515.28 ORY18344.1 - 0.0004 20.1 0.1 0.015 15.1 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 ORY18344.1 - 0.012 15.7 0.1 0.23 11.7 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Rho_Binding PF08912.11 ORY18344.1 - 0.97 10.3 3.6 1.8 9.4 3.6 1.4 1 0 0 1 1 1 0 Rho Binding Radical_SAM PF04055.21 ORY18345.1 - 1.6e-10 41.6 0.0 2.6e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 ORY18345.1 - 4.4e-05 23.8 0.0 8.1e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 ORY18345.1 - 0.062 13.4 0.1 0.2 11.8 0.0 1.8 2 0 0 2 2 2 0 4Fe-4S single cluster domain KSHV_K8 PF07188.11 ORY18345.1 - 0.17 11.2 0.0 0.27 10.6 0.0 1.2 1 0 0 1 1 1 0 Kaposi's sarcoma-associated herpesvirus (KSHV) K8 protein Frankia_peptide PF14407.6 ORY18345.1 - 0.21 11.6 0.0 0.79 9.7 0.0 1.9 2 0 0 2 2 2 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. Pentapeptide PF00805.22 ORY18345.1 - 0.33 10.6 1.4 1.4 8.7 0.3 2.1 2 0 0 2 2 2 0 Pentapeptide repeats (8 copies) But2 PF09792.9 ORY18346.1 - 3.1e-24 86.0 0.2 3.6e-24 85.8 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain ADH_zinc_N PF00107.26 ORY18347.1 - 3.3e-11 43.3 0.2 5.9e-11 42.5 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ORY18347.1 - 2.5e-07 30.5 0.0 4.7e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 ORY18347.1 - 0.0033 18.5 0.0 0.0097 17.0 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 ORY18347.1 - 0.035 13.6 0.1 0.056 12.9 0.1 1.3 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus LPMO_10 PF03067.15 ORY18348.1 - 1.2e-13 52.2 0.7 1.7e-13 51.7 0.7 1.2 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Zn_clus PF00172.18 ORY18349.1 - 3.9e-06 26.9 5.3 6.1e-06 26.2 5.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.32 ORY18350.1 - 1.6e-40 136.3 1.6 3.1e-12 46.8 0.1 4.4 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY18350.1 - 1.1e-17 64.1 0.1 1e-05 25.7 0.0 4.0 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 ORY18350.1 - 5.6e-11 42.0 0.1 0.017 14.1 0.0 3.8 1 1 3 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Proteasome_A_N PF10584.9 ORY18350.1 - 7.2e-09 35.2 0.0 0.23 11.2 0.0 4.5 4 0 0 4 4 4 3 Proteasome subunit A N-terminal signature PD40 PF07676.12 ORY18350.1 - 1.5e-08 34.4 0.4 0.2 11.6 0.0 4.3 4 0 0 4 4 4 3 WD40-like Beta Propeller Repeat IKI3 PF04762.12 ORY18350.1 - 3.1e-05 22.2 0.1 0.0017 16.4 0.1 2.7 1 1 1 2 2 2 2 IKI3 family Ret2_MD PF18528.1 ORY18350.1 - 0.0014 19.0 0.0 37 4.8 0.0 3.9 1 1 3 4 4 4 0 RNA editing 3' terminal uridylyl transferase 2 middle domain WD40_like PF17005.5 ORY18350.1 - 0.0022 17.4 0.0 6.5 6.0 0.0 3.1 3 0 0 3 3 3 2 WD40-like domain Gmad1 PF10647.9 ORY18350.1 - 0.0044 16.8 1.5 1.9 8.2 0.2 2.5 1 1 1 2 2 2 2 Lipoprotein LpqB beta-propeller domain DUF5122 PF17164.4 ORY18350.1 - 0.0074 16.6 0.0 12 6.3 0.0 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF5122) beta-propeller TruB_C PF09142.11 ORY18350.1 - 0.024 14.4 0.0 41 4.0 0.0 3.6 4 0 0 4 4 4 0 tRNA Pseudouridine synthase II, C terminal Nup160 PF11715.8 ORY18350.1 - 0.03 13.0 0.0 3.8 6.0 0.0 2.6 1 1 2 3 3 3 0 Nucleoporin Nup120/160 DPPIV_N PF00930.21 ORY18350.1 - 0.11 11.2 0.2 23 3.6 0.0 3.3 3 1 0 4 4 4 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region PSII_BNR PF14870.6 ORY18350.1 - 0.12 11.6 0.1 14 4.8 0.0 2.0 1 1 0 2 2 2 0 Photosynthesis system II assembly factor YCF48 Methyltransf_3 PF01596.17 ORY18350.1 - 0.16 11.1 0.0 20 4.3 0.0 3.3 2 1 2 4 4 4 0 O-methyltransferase RAB3GAP2_N PF14655.6 ORY18350.1 - 0.21 10.8 0.0 1.5 8.0 0.0 2.2 2 1 1 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus NACHT PF05729.12 ORY18351.1 - 1.2e-09 38.4 0.0 1.6e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 ORY18351.1 - 8.5e-09 36.0 0.2 1.3e-08 35.4 0.2 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 ORY18351.1 - 0.00025 21.3 0.0 0.00041 20.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 ORY18351.1 - 0.00068 20.2 0.6 0.012 16.2 0.6 2.2 1 1 0 1 1 1 1 AAA domain APS_kinase PF01583.20 ORY18351.1 - 0.0033 17.3 0.0 0.0067 16.3 0.0 1.5 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_33 PF13671.6 ORY18351.1 - 0.042 14.0 0.1 0.089 12.9 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 ORY18351.1 - 0.062 13.0 0.0 0.088 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 ORY18351.1 - 0.067 13.6 0.0 0.14 12.6 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Cytidylate_kin PF02224.18 ORY18351.1 - 0.077 12.7 0.0 0.74 9.5 0.0 2.0 2 0 0 2 2 2 0 Cytidylate kinase NB-ARC PF00931.22 ORY18351.1 - 0.18 11.0 0.0 0.35 10.0 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.22 ORY18351.1 - 0.23 11.9 0.1 0.72 10.3 0.0 1.9 2 0 0 2 2 2 0 RNA helicase HeLo PF14479.6 ORY18352.1 - 5.1e-40 137.5 4.4 5.2e-39 134.2 4.4 2.0 1 1 0 1 1 1 1 Prion-inhibition and propagation GIDA_assoc PF13932.6 ORY18352.1 - 0.014 15.6 1.2 0.014 15.6 1.2 1.6 1 1 1 2 2 2 0 GidA associated domain Rhomboid PF01694.22 ORY18354.1 - 4.8e-19 68.8 9.6 8.3e-19 68.1 9.6 1.3 1 0 0 1 1 1 1 Rhomboid family AA_permease_2 PF13520.6 ORY18355.1 - 1.1e-20 73.9 7.5 1.3e-20 73.7 7.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ORY18355.1 - 4.8e-10 38.6 5.4 5.7e-10 38.4 5.4 1.0 1 0 0 1 1 1 1 Amino acid permease OPT PF03169.15 ORY18357.1 - 1.4e-13 50.4 0.2 1.6e-13 50.2 0.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Swm2 PF17083.5 ORY18358.1 - 0.024 14.6 0.1 0.043 13.8 0.1 1.3 1 0 0 1 1 1 0 Nucleolar protein Swm2 PEMT PF04191.13 ORY18359.1 - 1.5e-58 195.7 9.4 5.4e-36 123.2 1.2 2.5 2 0 0 2 2 2 2 Phospholipid methyltransferase YWFCY PF14293.6 ORY18359.1 - 0.0047 17.2 0.3 0.02 15.2 0.3 2.1 1 0 0 1 1 1 1 YWFCY protein SKICH PF17751.1 ORY18359.1 - 0.057 14.0 0.0 1.4 9.5 0.0 2.3 2 0 0 2 2 2 0 SKICH domain HECW_N PF16562.5 ORY18359.1 - 0.068 13.0 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 Methyltransf_33 PF10017.9 ORY18361.1 - 5.4e-91 304.9 0.0 7.2e-91 304.5 0.0 1.1 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.16 ORY18361.1 - 3.7e-22 79.1 0.8 7.5e-20 71.6 1.1 2.5 2 1 0 2 2 2 1 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.7 ORY18361.1 - 0.00057 20.4 1.0 0.0021 18.6 1.0 2.1 1 1 0 1 1 1 1 DinB superfamily Lon_C PF05362.13 ORY18363.1 - 5.7e-67 225.2 0.1 1e-66 224.4 0.1 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 ORY18363.1 - 2e-27 96.4 1.7 3.1e-27 95.8 0.0 2.0 2 0 0 2 2 2 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 ORY18363.1 - 1.3e-23 83.8 0.0 7.1e-23 81.5 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 ORY18363.1 - 7.2e-09 35.8 0.0 3.4e-08 33.6 0.0 2.3 2 0 0 2 2 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.6 ORY18363.1 - 4.9e-07 29.6 0.5 1.1e-06 28.4 0.0 1.9 2 0 0 2 2 2 1 Subunit ChlI of Mg-chelatase AAA_16 PF13191.6 ORY18363.1 - 2e-05 25.0 0.4 6.8e-05 23.3 0.0 2.1 2 0 0 2 2 1 1 AAA ATPase domain TIP49 PF06068.13 ORY18363.1 - 8.5e-05 21.9 0.0 0.00017 20.9 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain IstB_IS21 PF01695.17 ORY18363.1 - 8.7e-05 22.3 0.0 0.00024 20.9 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_3 PF07726.11 ORY18363.1 - 9.1e-05 22.3 0.0 0.00043 20.2 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 ORY18363.1 - 0.00043 20.1 0.1 0.0016 18.2 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 ORY18363.1 - 0.00045 20.5 0.0 0.013 15.8 0.0 2.8 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.14 ORY18363.1 - 0.00093 19.4 0.0 0.0028 17.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 ORY18363.1 - 0.0047 17.1 0.0 0.011 15.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_PrkA PF08298.11 ORY18363.1 - 0.017 14.0 0.3 0.49 9.2 0.1 2.2 2 0 0 2 2 2 0 PrkA AAA domain Mg_chelatase PF01078.21 ORY18363.1 - 0.019 14.4 0.2 0.047 13.1 0.2 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 ORY18363.1 - 0.02 15.3 0.0 0.044 14.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_23 PF13476.6 ORY18363.1 - 0.021 15.4 0.2 0.021 15.4 0.2 2.9 1 1 1 2 2 1 0 AAA domain NACHT PF05729.12 ORY18363.1 - 0.023 14.6 0.0 0.07 13.0 0.0 1.8 1 0 0 1 1 1 0 NACHT domain AAA_7 PF12775.7 ORY18363.1 - 0.04 13.4 0.0 0.076 12.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Rad17 PF03215.15 ORY18363.1 - 0.05 13.5 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain TsaE PF02367.17 ORY18363.1 - 0.05 13.6 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 ORY18363.1 - 0.057 14.0 0.8 0.13 12.8 0.1 2.0 2 0 0 2 2 1 0 AAA domain AAA_30 PF13604.6 ORY18363.1 - 0.059 13.1 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 ORY18363.1 - 0.062 12.9 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 ORY18363.1 - 0.064 12.7 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein ABC_tran PF00005.27 ORY18363.1 - 0.071 13.6 0.5 0.28 11.7 0.0 2.2 2 1 0 2 2 2 0 ABC transporter AAA_24 PF13479.6 ORY18363.1 - 0.1 12.3 0.1 0.2 11.4 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 ORY18363.1 - 0.11 12.9 0.0 0.37 11.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain DUF2408 PF10303.9 ORY18363.1 - 2.2 8.8 6.5 5.6 7.5 5.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) AAA_11 PF13086.6 ORY18363.1 - 4.7 6.9 10.8 0.21 11.4 0.2 2.2 1 1 1 2 2 2 0 AAA domain p450 PF00067.22 ORY18364.1 - 1.6e-47 162.3 0.0 2.5e-47 161.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PSS PF03034.15 ORY18369.1 - 0.042 13.6 3.5 0.067 12.9 3.5 1.3 1 0 0 1 1 1 0 Phosphatidyl serine synthase DUF3325 PF11804.8 ORY18369.1 - 1.8 8.7 8.4 0.23 11.6 1.8 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3325) Acetyltransf_7 PF13508.7 ORY18371.1 - 9.8e-07 29.1 0.1 2.3e-06 27.9 0.1 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORY18371.1 - 5.3e-06 26.7 0.0 1.3e-05 25.4 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ORY18371.1 - 8.5e-06 25.7 0.0 2.1e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3328 PF11807.8 ORY18372.1 - 2.6e-22 79.7 0.3 3.3e-22 79.4 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) AA_permease_2 PF13520.6 ORY18373.1 - 2.5e-49 168.2 47.2 3.3e-49 167.9 47.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ORY18373.1 - 1.9e-27 96.1 34.5 1.9e-27 96.1 34.5 2.0 2 0 0 2 2 2 1 Amino acid permease Pro_CA PF00484.19 ORY18375.1 - 1.1e-05 25.8 0.0 0.0083 16.4 0.0 2.2 2 0 0 2 2 2 2 Carbonic anhydrase HD PF01966.22 ORY18376.1 - 2.6e-07 30.9 0.1 3.8e-07 30.3 0.1 1.3 1 0 0 1 1 1 1 HD domain p450 PF00067.22 ORY18378.1 - 1.3e-66 225.3 0.0 1.5e-66 225.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 RNA_pol PF00940.19 ORY18380.1 - 5.1e-184 611.9 0.1 8.7e-184 611.1 0.1 1.4 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 ORY18380.1 - 4.1e-83 279.6 1.7 4.1e-83 279.6 1.7 1.9 2 0 0 2 2 2 1 DNA-directed RNA polymerase N-terminal PPR_2 PF13041.6 ORY18380.1 - 0.0088 16.2 0.0 0.022 14.9 0.0 1.6 1 0 0 1 1 1 1 PPR repeat family LPG_synthase_TM PF03706.13 ORY18382.1 - 0.025 14.1 0.4 0.03 13.9 0.4 1.1 1 0 0 1 1 1 0 Lysylphosphatidylglycerol synthase TM region PBP_N PF17093.5 ORY18382.1 - 0.071 13.4 0.0 0.083 13.1 0.0 1.2 1 0 0 1 1 1 0 Penicillin-binding protein N-terminus GPI PF06560.11 ORY18383.1 - 0.18 11.0 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) FYVE_2 PF02318.16 ORY18385.1 - 0.0043 17.2 23.9 0.87 9.8 2.0 3.4 3 0 0 3 3 3 3 FYVE-type zinc finger FAP PF07174.11 ORY18385.1 - 0.88 9.0 20.5 2 7.8 20.5 1.6 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) HypA PF01155.19 ORY18385.1 - 3.3 7.7 26.2 1.7 8.7 3.0 3.5 3 0 0 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Siva PF05458.12 ORY18385.1 - 4.2 7.0 25.4 2 8.1 4.0 3.3 3 0 0 3 3 3 0 Cd27 binding protein (Siva) SNF2_N PF00176.23 ORY18389.1 - 2.3e-56 191.0 1.2 4.3e-55 186.9 1.2 2.1 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ORY18389.1 - 1.3e-13 51.3 0.0 1.2e-12 48.1 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain PHD PF00628.29 ORY18389.1 - 0.00015 21.6 3.7 0.00015 21.6 3.7 2.9 3 0 0 3 3 3 2 PHD-finger HDA2-3 PF11496.8 ORY18389.1 - 0.0038 16.4 0.0 0.0094 15.1 0.0 1.6 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DUF1518 PF07469.12 ORY18389.1 - 0.44 11.0 2.1 1.5 9.3 2.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1518) Zf_RING PF16744.5 ORY18389.1 - 1.2 9.3 8.6 20 5.4 0.7 3.6 3 0 0 3 3 3 0 KIAA1045 RING finger zf-PHD-like PF15446.6 ORY18389.1 - 1.5 8.4 10.1 2.6 7.7 7.3 2.7 1 1 1 2 2 2 0 PHD/FYVE-zinc-finger like domain Clr2_transil PF16761.5 ORY18390.1 - 6.5e-23 81.3 0.1 1.2e-22 80.5 0.1 1.4 1 0 0 1 1 1 1 Transcription-silencing protein, cryptic loci regulator Clr2 Clr2 PF10383.9 ORY18390.1 - 2.1e-12 48.0 0.2 9.5e-12 45.9 0.0 2.2 2 1 0 2 2 2 1 Transcription-silencing protein Clr2 HET PF06985.11 ORY18391.1 - 7e-26 91.3 0.0 9.2e-26 90.9 0.0 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF1601 PF07671.11 ORY18391.1 - 0.12 12.2 0.5 0.4 10.6 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1601) Pkinase_fungal PF17667.1 ORY18394.1 - 0.067 12.0 2.4 0.12 11.1 2.4 1.3 1 0 0 1 1 1 0 Fungal protein kinase adh_short PF00106.25 ORY18397.1 - 7.5e-30 103.9 0.0 8.9e-30 103.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY18397.1 - 1.6e-14 54.1 0.1 2e-14 53.8 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY18397.1 - 0.001 19.1 0.0 0.0015 18.5 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF5408 PF17402.2 ORY18397.1 - 0.17 11.8 0.0 0.31 11.0 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5408) ADH_zinc_N PF00107.26 ORY18398.1 - 3.7e-09 36.7 0.0 7e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ORY18398.1 - 0.013 15.4 0.0 0.058 13.3 0.0 1.9 1 1 1 2 2 2 0 Alcohol dehydrogenase GroES-like domain MFS_1 PF07690.16 ORY18399.1 - 2.4e-41 141.8 46.4 2.4e-41 141.8 46.4 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 ORY18399.1 - 4.2e-12 45.3 18.3 5.7e-12 44.9 18.3 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Phage_holin_3_2 PF04550.12 ORY18399.1 - 0.87 10.2 10.8 0.44 11.1 4.6 3.4 3 0 0 3 3 3 0 Phage holin family 2 Zn_clus PF00172.18 ORY18400.1 - 4.2e-08 33.2 7.8 8e-08 32.3 7.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UPF0506 PF11703.8 ORY18400.1 - 0.18 12.2 4.3 0.41 11.0 4.3 1.6 1 0 0 1 1 1 0 UPF0506 Serglycin PF04360.12 ORY18400.1 - 0.41 10.6 3.2 3.7 7.5 0.0 2.4 2 0 0 2 2 2 0 Serglycin FAD_binding_4 PF01565.23 ORY18401.1 - 5.6e-20 71.5 0.1 1.2e-19 70.4 0.1 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 ORY18401.1 - 0.0014 18.7 0.1 0.0038 17.3 0.1 1.7 1 0 0 1 1 1 1 Berberine and berberine like ketoacyl-synt PF00109.26 ORY18402.1 - 1.1e-74 251.2 0.0 2.6e-74 250.0 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain AMP-binding PF00501.28 ORY18402.1 - 6e-72 242.5 0.0 1.2e-71 241.5 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 ORY18402.1 - 1.9e-64 218.0 0.5 3.1e-64 217.4 0.5 1.2 1 0 0 1 1 1 1 Condensation domain PS-DH PF14765.6 ORY18402.1 - 1e-49 169.4 0.0 2e-49 168.5 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 ORY18402.1 - 3e-46 157.6 0.0 6.9e-45 153.2 0.0 2.7 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.21 ORY18402.1 - 4.5e-36 125.0 0.3 1.3e-35 123.5 0.3 1.8 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 ORY18402.1 - 8e-32 109.7 0.2 3e-31 107.9 0.0 2.2 2 0 0 2 2 1 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.12 ORY18402.1 - 5.8e-30 104.3 0.0 2.1e-29 102.5 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein PP-binding PF00550.25 ORY18402.1 - 1.3e-21 76.7 1.5 3.1e-12 46.6 0.0 3.1 3 0 0 3 3 2 2 Phosphopantetheine attachment site Methyltransf_12 PF08242.12 ORY18402.1 - 1.2e-19 70.8 0.0 4.5e-19 69.0 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 ORY18402.1 - 1.7e-13 51.0 0.0 6.1e-13 49.2 0.0 2.0 2 0 0 2 2 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_23 PF13489.6 ORY18402.1 - 2.1e-13 50.4 0.0 6e-13 49.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY18402.1 - 5.4e-12 46.3 0.0 3.4e-11 43.7 0.0 2.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY18402.1 - 9.7e-10 39.0 0.0 4.9e-09 36.7 0.0 2.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY18402.1 - 2.1e-09 37.4 0.0 6.2e-09 35.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 ORY18402.1 - 1.2e-07 31.4 0.0 7.9e-07 28.7 0.0 2.4 2 0 0 2 2 2 1 short chain dehydrogenase Thiolase_N PF00108.23 ORY18402.1 - 4.1e-06 26.3 0.2 2e-05 24.1 0.2 2.1 2 0 0 2 2 2 1 Thiolase, N-terminal domain AMP-binding_C PF13193.6 ORY18402.1 - 0.0031 18.5 0.0 0.012 16.6 0.0 2.2 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Methyltransf_16 PF10294.9 ORY18402.1 - 0.0087 15.8 0.0 0.022 14.5 0.0 1.6 1 0 0 1 1 1 1 Lysine methyltransferase Ubie_methyltran PF01209.18 ORY18402.1 - 0.017 14.5 0.0 0.094 12.0 0.0 2.0 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Sacchrp_dh_NADP PF03435.18 ORY18402.1 - 0.031 14.5 0.1 5.7 7.2 0.1 3.1 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain NodS PF05401.11 ORY18402.1 - 0.044 13.4 0.0 0.14 11.7 0.0 1.9 1 0 0 1 1 1 0 Nodulation protein S (NodS) MTS PF05175.14 ORY18402.1 - 0.059 12.9 0.0 0.15 11.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase small domain FAD_binding_3 PF01494.19 ORY18403.1 - 1.7e-19 70.3 0.1 2.4e-10 40.2 0.0 2.8 2 1 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 ORY18403.1 - 3.2e-06 26.6 0.0 0.0056 16.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORY18403.1 - 9.6e-06 25.7 0.0 2.8e-05 24.3 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 ORY18403.1 - 3.4e-05 23.1 0.0 0.00012 21.3 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 ORY18403.1 - 0.00083 19.9 0.0 0.068 13.7 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ORY18403.1 - 0.0047 16.6 0.1 0.039 13.5 0.0 2.0 1 1 1 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 ORY18403.1 - 0.019 14.2 0.0 0.48 9.6 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 ORY18403.1 - 0.019 14.3 0.7 0.71 9.1 0.0 2.7 3 1 0 3 3 3 0 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.12 ORY18403.1 - 0.086 11.9 0.0 0.17 10.9 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein SE PF08491.10 ORY18403.1 - 0.22 10.6 0.0 0.4 9.7 0.0 1.4 1 0 0 1 1 1 0 Squalene epoxidase DIOX_N PF14226.6 ORY18404.1 - 7.4e-25 88.0 0.0 1.2e-24 87.3 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 ORY18404.1 - 1.4e-20 73.6 0.0 2.4e-20 72.9 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Methyltransf_2 PF00891.18 ORY18405.1 - 2.5e-19 69.4 0.0 4.2e-19 68.7 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Alpha_TIF PF02232.15 ORY18405.1 - 0.083 12.0 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Alpha trans-inducing protein (Alpha-TIF) p450 PF00067.22 ORY18406.1 - 2.1e-36 125.7 0.0 2.8e-36 125.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 AA_permease PF00324.21 ORY18407.1 - 6.8e-70 236.0 24.8 1.1e-62 212.2 19.0 2.1 2 0 0 2 2 2 2 Amino acid permease AA_permease_2 PF13520.6 ORY18407.1 - 6.3e-26 91.2 23.6 8.4e-26 90.8 23.6 1.2 1 0 0 1 1 1 1 Amino acid permease DUF485 PF04341.12 ORY18407.1 - 0.74 9.8 5.7 0.4 10.7 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function, DUF485 Capsid_N PF16903.5 ORY18408.1 - 0.15 11.6 0.0 0.26 10.9 0.0 1.2 1 0 0 1 1 1 0 Major capsid protein N-terminus DUF4684 PF15736.5 ORY18408.1 - 0.16 10.7 1.2 0.26 9.9 1.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4684) Methyltransf_11 PF08241.12 ORY18410.1 - 1.6e-13 51.1 0.0 6e-12 46.1 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY18410.1 - 1.9e-12 47.7 0.0 5.6e-11 43.0 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORY18410.1 - 4.6e-09 36.0 0.0 2.2e-08 33.7 0.0 1.8 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 ORY18410.1 - 5e-08 33.6 0.0 2.3e-07 31.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY18410.1 - 0.00069 19.5 0.0 0.001 18.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY18410.1 - 0.0018 18.1 0.0 0.0024 17.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MFS_1 PF07690.16 ORY18411.1 - 7.2e-32 110.7 27.8 9.1e-32 110.3 27.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 ORY18411.1 - 3.1e-06 26.7 1.6 3.1e-06 26.7 1.6 2.2 2 1 1 3 3 3 1 Uncharacterised MFS-type transporter YbfB DUF5050 PF16472.5 ORY18412.1 - 1.8e-05 24.1 0.2 2.6e-05 23.6 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF5050) HET PF06985.11 ORY18413.1 - 3.3e-35 121.6 0.2 5.8e-35 120.8 0.2 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) UvrD-helicase PF00580.21 ORY18415.1 - 3.5e-11 43.2 0.3 2.8e-08 33.7 0.0 2.4 2 0 0 2 2 2 2 UvrD/REP helicase N-terminal domain AAA_19 PF13245.6 ORY18415.1 - 7.6e-10 39.3 0.0 1.8e-09 38.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 ORY18415.1 - 3.6e-06 26.9 0.1 0.12 12.1 0.0 3.3 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.6 ORY18415.1 - 4.2e-06 26.5 0.0 8.3e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_12 PF13087.6 ORY18415.1 - 0.00013 21.6 0.0 0.0027 17.3 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 ORY18415.1 - 0.01 15.6 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 ORY18415.1 - 0.013 14.9 0.0 2.5 7.5 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein AAA_16 PF13191.6 ORY18415.1 - 0.019 15.3 0.1 0.073 13.4 0.1 1.9 1 1 0 1 1 1 0 AAA ATPase domain UvrD_C PF13361.6 ORY18415.1 - 0.047 13.1 0.0 0.16 11.3 0.0 1.8 1 1 1 2 2 2 0 UvrD-like helicase C-terminal domain AAA PF00004.29 ORY18415.1 - 0.17 12.3 0.0 0.47 10.9 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AflR PF08493.10 ORY18416.1 - 7.5e-09 35.5 6.4 7.5e-09 35.5 6.4 2.5 2 1 0 2 2 2 1 Aflatoxin regulatory protein Zn_clus PF00172.18 ORY18416.1 - 5.7e-07 29.5 13.4 1.1e-06 28.6 13.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-CCHC_4 PF14392.6 ORY18417.1 - 0.063 13.0 0.2 0.14 11.9 0.2 1.6 1 0 0 1 1 1 0 Zinc knuckle Melibiase_2 PF16499.5 ORY18419.1 - 4e-66 223.1 6.3 7.8e-66 222.1 6.3 1.5 1 1 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 ORY18419.1 - 1.7e-11 44.0 0.5 7e-10 38.8 0.2 2.5 2 0 0 2 2 2 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 ORY18419.1 - 3.7e-05 22.9 0.5 6.2e-05 22.1 0.0 1.5 2 0 0 2 2 2 1 Melibiase zf-C2H2_4 PF13894.6 ORY18420.1 - 0.042 14.7 12.6 0.8 10.7 4.5 3.1 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 ORY18420.1 - 0.06 13.8 10.9 2.1 9.0 0.7 3.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-Di19 PF05605.12 ORY18420.1 - 4.9 7.5 7.2 1.5 9.2 3.4 2.1 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Abhydrolase_1 PF00561.20 ORY18422.1 - 1.7e-09 37.7 0.0 5.2e-09 36.1 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORY18422.1 - 2.1e-09 38.3 0.9 2.7e-09 37.9 0.9 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORY18422.1 - 0.0053 16.0 0.0 0.023 14.0 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 ORY18422.1 - 0.02 15.0 0.0 0.045 13.9 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein Cadherin_3 PF16184.5 ORY18422.1 - 0.17 11.9 0.0 0.33 11.0 0.0 1.4 1 0 0 1 1 1 0 Cadherin-like ketoacyl-synt PF00109.26 ORY18423.1 - 3.4e-69 233.3 0.0 6.2e-69 232.4 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.6 ORY18423.1 - 6.8e-63 212.7 0.0 1.3e-62 211.7 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 ORY18423.1 - 3.6e-52 176.9 0.4 1e-50 172.2 0.1 2.5 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.21 ORY18423.1 - 2.7e-48 165.1 0.1 4.8e-48 164.3 0.1 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 ORY18423.1 - 5.7e-36 123.1 0.1 1.6e-35 121.7 0.1 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 ORY18423.1 - 2.4e-18 66.6 0.0 8.4e-18 64.9 0.0 2.0 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 ORY18423.1 - 8.7e-14 51.4 0.5 8.8e-12 44.9 0.1 2.4 2 0 0 2 2 2 1 short chain dehydrogenase ADH_zinc_N PF00107.26 ORY18423.1 - 4.4e-12 46.1 0.0 5.2e-11 42.6 0.0 2.4 2 0 0 2 2 2 1 Zinc-binding dehydrogenase adh_short_C2 PF13561.6 ORY18423.1 - 4.5e-11 42.7 0.7 2e-10 40.6 0.1 2.1 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase ADH_zinc_N_2 PF13602.6 ORY18423.1 - 2e-08 35.4 0.0 1.6e-06 29.2 0.0 2.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Thiolase_N PF00108.23 ORY18423.1 - 8e-06 25.4 0.1 1.5e-05 24.5 0.1 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain PP-binding PF00550.25 ORY18423.1 - 5.7e-05 23.4 0.3 0.00014 22.1 0.3 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_12 PF08242.12 ORY18423.1 - 0.0014 19.4 0.0 0.0079 16.9 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY18423.1 - 0.0016 18.3 0.0 0.006 16.4 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY18423.1 - 0.0046 17.6 0.1 2 9.1 0.0 3.6 3 0 0 3 3 3 1 Methyltransferase domain ACP_syn_III PF08545.10 ORY18423.1 - 0.019 14.8 0.2 0.092 12.6 0.2 2.2 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ADH_N PF08240.12 ORY18423.1 - 0.025 14.5 0.1 0.056 13.3 0.1 1.6 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain Methyltransf_31 PF13847.6 ORY18423.1 - 0.056 13.2 0.0 0.91 9.3 0.0 2.7 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_2 PF00891.18 ORY18424.1 - 1e-19 70.7 0.0 1.8e-19 69.9 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_25 PF13649.6 ORY18424.1 - 8.2e-07 29.7 0.0 1.7e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY18424.1 - 0.007 17.0 0.0 0.014 16.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORY18424.1 - 0.0089 15.4 0.0 0.017 14.4 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 ORY18424.1 - 0.022 14.3 0.0 0.042 13.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_18 PF12847.7 ORY18424.1 - 0.067 13.1 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain CheR PF01739.18 ORY18424.1 - 0.078 12.5 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Methyltransf_12 PF08242.12 ORY18424.1 - 0.11 13.3 0.0 0.33 11.7 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain DUF4423 PF14394.6 ORY18424.1 - 0.12 12.1 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) Methyltransf_31 PF13847.6 ORY18424.1 - 0.15 11.9 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.6 ORY18424.1 - 0.18 11.8 0.1 0.39 10.7 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain DUF2569 PF10754.9 ORY18425.1 - 1 9.8 13.1 0.2 12.1 9.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2569) Abhydrolase_1 PF00561.20 ORY18426.1 - 4e-19 69.3 0.2 3.3e-16 59.7 0.2 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORY18426.1 - 8.2e-18 65.8 1.1 1.5e-17 64.9 1.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORY18426.1 - 5.6e-08 32.3 0.0 2.9e-07 30.0 0.0 2.0 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Ndr PF03096.14 ORY18426.1 - 0.0096 14.7 0.0 0.015 14.0 0.0 1.2 1 0 0 1 1 1 1 Ndr family RCC1_2 PF13540.6 ORY18427.1 - 0.11 12.4 0.1 0.25 11.2 0.1 1.6 1 0 0 1 1 1 0 Regulator of chromosome condensation (RCC1) repeat LEDGF PF11467.8 ORY18427.1 - 0.14 11.8 0.0 0.22 11.2 0.0 1.2 1 0 0 1 1 1 0 Lens epithelium-derived growth factor (LEDGF) PSII_Pbs27 PF13326.6 ORY18427.1 - 0.19 12.1 0.0 0.26 11.6 0.0 1.2 1 0 0 1 1 1 0 Photosystem II Pbs27 Pkinase PF00069.25 ORY18496.1 - 0.018 14.4 0.0 0.018 14.4 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain XTBD PF11952.8 ORY18496.1 - 0.12 12.1 0.1 0.15 11.8 0.1 1.2 1 0 0 1 1 1 0 XRN-Two Binding Domain, XTBD Tachystatin_A PF11406.8 ORY18497.1 - 6.2e-06 26.2 4.7 40 4.4 0.0 6.0 6 0 0 6 6 6 5 Antimicrobial peptide tachystatin A TAT_ubiq PF07706.12 ORY18497.1 - 5 7.4 14.3 1.4e+02 2.8 0.1 5.3 5 0 0 5 5 5 0 Aminotransferase ubiquitination site DUF3328 PF11807.8 ORY18498.1 - 3.5e-49 167.6 0.4 4.1e-49 167.3 0.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) ADP_ribosyl_GH PF03747.14 ORY18500.1 - 2e-52 178.8 0.0 2.7e-52 178.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase Gly-zipper_Omp PF13488.6 ORY18500.1 - 0.037 14.0 2.5 2.9 8.0 0.5 3.1 3 0 0 3 3 3 0 Glycine zipper Rick_17kDa_Anti PF05433.15 ORY18500.1 - 1.7 8.5 7.3 8.3 6.4 1.2 3.1 3 0 0 3 3 3 0 Glycine zipper 2TM domain Gly-zipper_YMGG PF13441.6 ORY18500.1 - 3.7 7.4 6.1 64 3.4 2.9 3.0 3 0 0 3 3 3 0 YMGG-like Gly-zipper Hyccin PF09790.9 ORY18502.1 - 0.022 13.9 0.6 0.025 13.7 0.6 1.0 1 0 0 1 1 1 0 Hyccin EcoRII-N PF09217.10 ORY18502.1 - 0.078 12.7 0.0 0.088 12.6 0.0 1.1 1 0 0 1 1 1 0 Restriction endonuclease EcoRII, N-terminal CAP_N PF01213.19 ORY18503.1 - 8.7e-106 354.0 7.8 8.7e-106 354.0 7.8 1.9 1 1 1 2 2 2 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 ORY18503.1 - 4.2e-61 205.2 1.1 6.2e-61 204.6 1.1 1.3 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.12 ORY18503.1 - 0.0083 15.9 3.7 0.017 14.8 1.5 2.0 1 1 1 2 2 2 1 Tubulin binding cofactor C DUF1987 PF09345.10 ORY18503.1 - 0.22 11.2 0.4 0.72 9.5 0.1 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1987) Mito_fiss_reg PF05308.11 ORY18503.1 - 2.9 7.9 0.0 2.9 7.9 0.0 3.2 2 1 1 3 3 3 0 Mitochondrial fission regulator PfkB PF00294.24 ORY18504.1 - 3e-10 39.9 0.0 4.3e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase dsrm PF00035.26 ORY18506.1 - 6.2e-06 26.8 0.0 1.3e-05 25.8 0.0 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonucleas_3_3 PF14622.6 ORY18506.1 - 0.035 14.3 0.0 1.5 9.0 0.0 2.2 2 0 0 2 2 2 0 Ribonuclease-III-like Ribonuclease_3 PF00636.26 ORY18506.1 - 0.04 14.5 0.0 0.1 13.2 0.0 1.9 1 1 0 1 1 1 0 Ribonuclease III domain Pkinase PF00069.25 ORY18508.1 - 6.4e-19 68.3 0.0 1.3e-18 67.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY18508.1 - 1.4e-11 44.1 0.0 3.2e-11 43.0 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase DUF5339 PF17274.2 ORY18511.1 - 0.0026 18.6 0.6 0.0026 18.6 0.6 1.6 2 0 0 2 2 2 1 Family of unknown function (DUF5339) Aminotran_5 PF00266.19 ORY18512.1 - 1.3e-20 73.7 0.0 3.2e-20 72.4 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class-V DUF4595 PF15283.6 ORY18512.1 - 0.14 12.3 0.0 0.2 11.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4595) with porin-like fold NmrA PF05368.13 ORY18513.1 - 2e-14 53.7 0.0 1e-12 48.1 0.0 2.0 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ORY18513.1 - 1.4e-06 28.3 0.0 2.4e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 ORY18513.1 - 0.00011 22.6 0.0 0.0002 21.8 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DXP_reductoisom PF02670.16 ORY18513.1 - 0.0039 17.9 0.0 0.01 16.6 0.0 1.6 1 1 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase F-box-like PF12937.7 ORY18514.1 - 0.03 14.2 0.0 0.071 13.0 0.0 1.7 1 0 0 1 1 1 0 F-box-like F-box PF00646.33 ORY18515.1 - 0.0026 17.6 0.0 3.5 7.6 0.0 2.8 2 1 0 2 2 2 2 F-box domain F-box-like PF12937.7 ORY18515.1 - 0.011 15.7 0.0 0.15 12.0 0.0 2.4 2 0 0 2 2 2 0 F-box-like RVT_1 PF00078.27 ORY18516.1 - 0.0027 17.3 0.0 0.0035 16.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) F-box PF00646.33 ORY18517.1 - 0.0003 20.6 2.5 0.033 14.1 0.2 2.2 2 0 0 2 2 2 2 F-box domain F-box-like PF12937.7 ORY18517.1 - 0.16 11.9 0.6 0.48 10.3 0.6 1.7 1 1 0 1 1 1 0 F-box-like Eaf7 PF07904.13 ORY18518.1 - 1.3e-25 89.9 0.0 1.3e-25 89.9 0.0 2.2 2 1 0 2 2 2 1 Chromatin modification-related protein EAF7 Sporozoite_P67 PF05642.11 ORY18518.1 - 0.15 10.1 7.4 0.24 9.4 7.4 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen FYDLN_acid PF09538.10 ORY18518.1 - 0.25 12.0 14.1 0.081 13.6 8.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) PBP1_TM PF14812.6 ORY18518.1 - 0.39 11.1 4.8 0.94 9.9 4.8 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NOA36 PF06524.12 ORY18518.1 - 1.6 8.0 6.0 2.4 7.4 6.0 1.2 1 0 0 1 1 1 0 NOA36 protein CDC27 PF09507.10 ORY18518.1 - 3.7 6.8 20.3 0.25 10.7 13.4 1.9 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 FAM60A PF15396.6 ORY18518.1 - 5.7 6.9 8.6 0.94 9.4 4.1 1.8 2 0 0 2 2 2 0 Protein Family FAM60A GCP_C_terminal PF04130.13 ORY18519.1 - 1.3e-71 241.6 0.2 2.3e-71 240.8 0.2 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 ORY18519.1 - 5.7e-26 91.9 0.0 1.3e-25 90.6 0.0 1.6 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal Acyl_transf_3 PF01757.22 ORY18520.1 - 2.2e-13 50.0 26.7 1.2e-12 47.5 26.7 2.1 1 1 0 1 1 1 1 Acyltransferase family PGAP1 PF07819.13 ORY18521.1 - 2e-90 302.5 0.0 3.1e-90 301.9 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 ORY18521.1 - 6.2e-06 27.0 0.9 1.4e-05 25.9 0.9 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORY18521.1 - 0.0032 16.8 0.0 0.008 15.5 0.0 1.6 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Palm_thioest PF02089.15 ORY18521.1 - 0.004 17.0 0.0 0.0064 16.3 0.0 1.3 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF676 PF05057.14 ORY18521.1 - 0.0091 15.5 0.1 0.017 14.6 0.1 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_1 PF00561.20 ORY18521.1 - 0.016 14.9 0.0 0.038 13.6 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold LCAT PF02450.15 ORY18521.1 - 0.043 13.0 0.0 0.069 12.3 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase V-SNARE_C PF12352.8 ORY18522.1 - 1.1e-13 51.2 1.9 6.9e-13 48.7 0.2 2.3 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 ORY18522.1 - 0.0012 18.7 0.0 0.005 16.7 0.0 2.0 2 1 0 2 2 2 1 Sec20 Mito_fiss_reg PF05308.11 ORY18522.1 - 0.03 14.4 2.4 0.038 14.1 2.4 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator HBM PF16591.5 ORY18522.1 - 0.071 12.5 0.4 0.15 11.5 0.4 1.4 1 0 0 1 1 1 0 Helical bimodular sensor domain Sigma70_r4 PF04545.16 ORY18522.1 - 0.16 11.5 0.7 0.27 10.8 0.1 1.7 2 0 0 2 2 2 0 Sigma-70, region 4 DUF3958 PF13125.6 ORY18522.1 - 0.3 11.3 2.5 4.6 7.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3958) Pyr_redox_2 PF07992.14 ORY18524.1 - 2.8e-44 151.5 0.1 4.3e-44 150.9 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NIR_SIR PF01077.22 ORY18524.1 - 1.8e-20 73.1 0.0 3.7e-20 72.0 0.0 1.5 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Pyr_redox PF00070.27 ORY18524.1 - 2.1e-15 57.0 6.3 4.3e-14 52.8 1.2 3.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Fer2_BFD PF04324.15 ORY18524.1 - 2.2e-15 56.8 7.0 2.2e-11 43.9 5.6 2.8 2 0 0 2 2 2 2 BFD-like [2Fe-2S] binding domain Rieske PF00355.26 ORY18524.1 - 4.3e-14 52.2 0.2 2.1e-13 50.0 0.0 2.2 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 ORY18524.1 - 3e-13 49.6 0.0 7.1e-13 48.4 0.0 1.7 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain NIR_SIR_ferr PF03460.17 ORY18524.1 - 1e-07 31.7 0.0 2.3e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain Rubredoxin_C PF18267.1 ORY18524.1 - 2.6e-05 24.0 0.0 0.069 13.1 0.0 3.2 3 0 0 3 3 3 2 Rubredoxin NAD+ reductase C-terminal domain NAD_binding_9 PF13454.6 ORY18524.1 - 0.0008 19.4 0.2 4.2 7.3 0.0 3.3 2 1 1 3 3 3 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 ORY18524.1 - 0.0026 17.1 0.0 0.0055 16.0 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Tsp45I PF06300.12 ORY18524.1 - 0.022 14.3 0.0 0.04 13.4 0.0 1.3 1 0 0 1 1 1 0 Tsp45I type II restriction enzyme K_oxygenase PF13434.6 ORY18524.1 - 0.2 10.8 0.0 2.1 7.4 0.0 2.0 1 1 1 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.21 ORY18524.1 - 0.22 10.8 0.3 20 4.4 0.0 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 ORY18524.1 - 0.28 10.2 0.7 14 4.7 0.3 2.7 2 1 1 3 3 3 0 Glucose inhibited division protein A Mo-co_dimer PF03404.16 ORY18525.1 - 8.7e-59 197.5 0.1 1.6e-58 196.6 0.1 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Oxidored_molyb PF00174.19 ORY18525.1 - 6.9e-52 175.5 0.0 1.3e-51 174.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain FAD_binding_6 PF00970.24 ORY18525.1 - 3.5e-34 117.1 0.0 6.6e-34 116.2 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 ORY18525.1 - 4.8e-27 94.8 0.0 1.1e-26 93.6 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.28 ORY18525.1 - 4.1e-22 78.1 0.0 9.1e-22 77.0 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 ORY18525.1 - 9.9e-05 22.5 0.1 0.035 14.2 0.0 2.7 2 1 1 3 3 3 2 Ferric reductase NAD binding domain ResIII PF04851.15 ORY18527.1 - 6.3e-25 88.1 0.0 1.8e-24 86.6 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 ORY18527.1 - 1.4e-14 54.3 0.0 3.9e-13 49.7 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 ORY18527.1 - 1.6e-10 41.0 0.0 3.7e-10 39.9 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 ORY18527.1 - 2.6e-05 24.0 0.0 9.2e-05 22.2 0.0 1.9 2 0 0 2 2 2 1 SWI2/SNF2 ATPase SwrA PF17423.2 ORY18527.1 - 0.013 15.4 0.0 0.033 14.2 0.0 1.6 1 0 0 1 1 1 0 Swarming motility protein DUF2075 PF09848.9 ORY18527.1 - 0.014 14.6 0.0 0.028 13.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 ORY18527.1 - 0.076 13.3 0.1 0.31 11.3 0.0 2.0 2 1 0 2 2 2 0 AAA domain Peptidase_M28 PF04389.17 ORY18529.1 - 8.9e-28 97.3 0.2 2.1e-27 96.1 0.2 1.6 1 1 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 ORY18529.1 - 6.1e-05 22.8 0.0 8e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 ORY18529.1 - 0.016 14.3 0.0 0.05 12.6 0.0 1.7 2 0 0 2 2 2 0 M42 glutamyl aminopeptidase MRJP PF03022.16 ORY18530.1 - 2e-10 40.5 0.0 3.3e-05 23.4 0.0 2.1 1 1 1 2 2 2 2 Major royal jelly protein Sec7 PF01369.20 ORY18531.1 - 4.2e-68 228.7 0.1 4.2e-68 228.7 0.1 3.4 5 0 0 5 5 5 1 Sec7 domain Sec7_N PF12783.7 ORY18531.1 - 1.4e-43 148.5 0.4 1.4e-43 148.5 0.4 2.8 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 ORY18531.1 - 4.2e-35 119.5 13.9 1.1e-32 111.7 0.1 7.0 7 0 0 7 7 7 2 Domain of unknown function (DUF1981) DCB PF16213.5 ORY18531.1 - 1.7e-20 73.4 8.5 1.9e-20 73.2 0.2 4.0 4 0 0 4 4 4 1 Dimerisation and cyclophilin-binding domain of Mon2 Peptidase_M13_N PF05649.13 ORY18531.1 - 0.016 14.9 0.1 0.058 13.1 0.0 2.1 2 0 0 2 2 2 0 Peptidase family M13 2-oxoacid_dh PF00198.23 ORY18532.1 - 3.2e-70 236.2 0.1 4.1e-70 235.9 0.1 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 ORY18532.1 - 6.5e-19 67.5 2.0 1.8e-18 66.1 1.2 2.2 1 1 1 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.17 ORY18532.1 - 3.6e-15 56.0 0.8 1e-14 54.6 0.5 2.0 2 0 0 2 2 2 1 e3 binding domain FAD_binding_4 PF01565.23 ORY18534.1 - 1.1e-16 60.8 0.5 1.9e-16 60.1 0.5 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 ORY18534.1 - 6.5e-12 45.4 0.1 1.4e-11 44.3 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like NmrA PF05368.13 ORY18536.1 - 3.3e-16 59.5 0.0 4.3e-16 59.2 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ORY18536.1 - 7.9e-09 35.7 0.0 1.4e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Carn_acyltransf PF00755.20 ORY18537.1 - 2.8e-203 676.8 0.0 3.2e-203 676.6 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Ldh_1_C PF02866.18 ORY18538.1 - 1e-43 149.2 0.0 2.9e-43 147.7 0.0 1.7 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 ORY18538.1 - 1.4e-42 145.1 0.0 2.1e-42 144.5 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 ORY18538.1 - 0.0047 16.0 0.0 0.0068 15.4 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DUF3303 PF11746.8 ORY18541.1 - 8.6e-16 58.0 0.0 1.1e-15 57.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3303) DUF4242 PF14026.6 ORY18541.1 - 0.11 12.6 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4242) Ferric_reduct PF01794.19 ORY18543.1 - 3.6e-24 85.3 10.9 3.6e-24 85.3 10.9 2.6 2 1 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 ORY18543.1 - 7.4e-16 58.7 0.0 2.1e-13 50.7 0.0 2.5 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 ORY18543.1 - 2.3e-06 27.7 0.0 0.011 15.9 0.0 2.5 2 0 0 2 2 2 2 FAD-binding domain NAD_binding_1 PF00175.21 ORY18543.1 - 0.16 12.6 0.1 1.2 9.8 0.1 2.3 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain DUF2158 PF09926.9 ORY18544.1 - 0.054 13.2 0.0 0.14 11.9 0.0 1.8 1 0 0 1 1 1 0 Uncharacterized small protein (DUF2158) Big_7 PF17957.1 ORY18544.1 - 0.17 12.7 0.3 0.17 12.7 0.3 2.7 1 1 0 2 2 2 0 Bacterial Ig domain Nbl1_Borealin_N PF10444.9 ORY18545.1 - 0.077 12.6 0.3 0.8 9.4 0.3 2.2 2 0 0 2 2 2 0 Nbl1 / Borealin N terminal F-box-like PF12937.7 ORY18547.1 - 0.0033 17.3 0.0 0.0089 15.9 0.0 1.8 1 0 0 1 1 1 1 F-box-like DUF866 PF05907.13 ORY18547.1 - 0.058 13.3 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF866) MIT_LIKE_ACTX PF17556.2 ORY18548.1 - 0.002 18.7 1.3 0.0034 17.9 1.3 1.3 1 0 0 1 1 1 1 MIT-like atracotoxin family ABC_tran PF00005.27 ORY18549.1 - 1.1e-47 162.0 0.0 3.8e-29 101.9 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 ORY18549.1 - 2.9e-27 96.0 36.7 5.7e-21 75.4 13.6 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 ORY18549.1 - 1.6e-10 40.8 2.3 0.19 11.1 0.0 4.4 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 ORY18549.1 - 2.2e-07 31.0 0.1 0.9 9.3 0.1 4.3 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 ORY18549.1 - 1.5e-05 24.9 0.3 0.17 11.8 0.1 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 ORY18549.1 - 1.8e-05 24.4 1.1 0.092 12.5 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 ORY18549.1 - 5.2e-05 23.5 0.5 0.26 11.6 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_7 PF12775.7 ORY18549.1 - 9.1e-05 22.0 0.0 0.59 9.6 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_16 PF13191.6 ORY18549.1 - 0.00011 22.6 0.1 0.14 12.5 0.1 2.8 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 ORY18549.1 - 0.00013 22.0 0.8 0.45 10.6 0.1 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase NB-ARC PF00931.22 ORY18549.1 - 0.00051 19.3 0.1 0.022 14.0 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain FtsK_SpoIIIE PF01580.18 ORY18549.1 - 0.0014 18.0 0.6 0.48 9.7 0.1 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family DUF815 PF05673.13 ORY18549.1 - 0.021 14.0 0.1 1.1 8.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_23 PF13476.6 ORY18549.1 - 0.022 15.3 0.3 4 7.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 ORY18549.1 - 0.025 14.1 0.4 10 5.6 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.6 ORY18549.1 - 0.027 14.6 0.1 3.9 7.6 0.0 2.8 2 0 0 2 2 2 0 AAA domain Adeno_IVa2 PF02456.15 ORY18549.1 - 0.029 13.2 0.3 0.1 11.4 0.0 1.8 2 0 0 2 2 2 0 Adenovirus IVa2 protein Dynamin_N PF00350.23 ORY18549.1 - 0.037 14.1 2.8 2.4 8.2 0.3 2.9 3 0 0 3 3 3 0 Dynamin family NACHT PF05729.12 ORY18549.1 - 0.042 13.8 1.4 3.3 7.6 0.1 2.9 2 0 0 2 2 2 0 NACHT domain RNA_helicase PF00910.22 ORY18549.1 - 0.071 13.5 0.3 21 5.5 0.0 3.5 4 0 0 4 4 3 0 RNA helicase DUF87 PF01935.17 ORY18549.1 - 0.088 12.9 5.3 0.2 11.7 0.1 2.7 3 0 0 3 3 2 0 Helicase HerA, central domain Roc PF08477.13 ORY18549.1 - 0.13 12.5 0.1 29 4.9 0.0 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Septin PF00735.18 ORY18549.1 - 0.14 11.4 0.1 9.3 5.4 0.0 2.3 2 0 0 2 2 2 0 Septin cobW PF02492.19 ORY18549.1 - 0.16 11.5 2.3 2.2 7.9 0.4 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Ycf4 PF02392.16 ORY18549.1 - 0.86 9.1 3.3 17 4.9 0.2 2.7 2 0 0 2 2 2 0 Ycf4 G-alpha PF00503.20 ORY18551.1 - 7.2e-116 387.2 0.0 8.3e-116 387.0 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 ORY18551.1 - 1.4e-15 57.1 1.5 7.9e-11 41.7 0.2 2.7 2 2 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 ORY18551.1 - 3.7e-05 23.2 0.2 0.091 12.1 0.0 2.2 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 ORY18551.1 - 0.0022 18.2 0.2 0.51 10.6 0.1 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase MCM PF00493.23 ORY18551.1 - 0.092 11.8 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain AAA_29 PF13555.6 ORY18551.1 - 0.11 12.2 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Pkinase PF00069.25 ORY18553.1 - 3e-67 226.8 0.0 3.9e-67 226.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY18553.1 - 1.1e-31 110.1 0.0 1.5e-31 109.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 ORY18553.1 - 8.5e-06 24.9 0.1 1.1e-05 24.5 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 ORY18553.1 - 6.2e-05 22.4 0.1 0.00021 20.7 0.1 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 ORY18553.1 - 0.00056 19.9 0.0 0.0014 18.6 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 ORY18553.1 - 0.0047 16.3 0.0 0.072 12.4 0.0 2.0 1 1 1 2 2 2 1 Kinase-like FTA2 PF13095.6 ORY18553.1 - 0.012 15.3 0.0 0.022 14.4 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 ORY18553.1 - 0.025 14.2 0.0 0.045 13.4 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Avl9 PF09794.9 ORY18554.1 - 1.8e-139 464.6 0.0 2.4e-139 464.3 0.0 1.1 1 0 0 1 1 1 1 Transport protein Avl9 SPA PF08616.10 ORY18554.1 - 1.2e-07 31.7 0.0 0.00029 20.8 0.0 2.5 2 0 0 2 2 2 2 Stabilization of polarity axis DUF2347 PF09804.9 ORY18554.1 - 7.8e-07 29.0 2.3 0.00053 19.7 0.3 3.6 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2347) DENN PF02141.21 ORY18554.1 - 0.012 15.6 0.1 0.058 13.3 0.0 2.1 2 0 0 2 2 2 0 DENN (AEX-3) domain ARGLU PF15346.6 ORY18554.1 - 0.25 11.2 6.1 0.43 10.4 6.1 1.2 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 GTP_EFTU PF00009.27 ORY18555.1 - 7.5e-35 120.2 1.7 1.5e-34 119.2 0.0 2.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 ORY18555.1 - 1.8e-17 63.4 0.1 5.6e-17 61.8 0.1 1.9 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 ORY18555.1 - 1e-10 41.9 0.1 1e-10 41.9 0.1 4.0 4 0 0 4 4 4 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.6 ORY18555.1 - 8.3e-10 38.4 0.5 3.4e-09 36.5 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.23 ORY18555.1 - 6.3e-07 29.5 0.2 9.4e-06 25.7 0.0 3.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase Roc PF08477.13 ORY18555.1 - 0.00046 20.4 0.0 0.0016 18.7 0.0 2.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 ORY18555.1 - 0.00079 19.3 0.0 0.00079 19.3 0.0 2.1 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein TrkA_C PF02080.21 ORY18555.1 - 0.071 13.0 1.6 7 6.6 0.1 3.3 3 0 0 3 3 3 0 TrkA-C domain AAA_22 PF13401.6 ORY18555.1 - 0.47 10.7 2.2 1.9 8.7 0.2 2.8 2 1 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 ORY18555.1 - 1.1 9.2 5.4 0.98 9.3 0.3 3.4 3 1 0 3 3 3 0 RsgA GTPase Chitin_synth_2 PF03142.15 ORY18556.1 - 4.6e-246 817.5 0.7 5.9e-246 817.2 0.7 1.1 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 ORY18556.1 - 1e-81 275.2 0.0 2.5e-81 273.9 0.0 1.6 1 1 0 1 1 1 1 Myosin head (motor domain) DEK_C PF08766.11 ORY18556.1 - 2e-16 59.7 0.4 5.1e-16 58.3 0.4 1.8 1 0 0 1 1 1 1 DEK C terminal domain Cyt-b5 PF00173.28 ORY18556.1 - 1.7e-15 56.9 0.3 2e-13 50.3 0.0 2.9 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain Glyco_tranf_2_3 PF13641.6 ORY18556.1 - 1.8e-12 47.7 0.1 1.8e-11 44.4 0.1 2.3 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 ORY18556.1 - 3.6e-12 46.6 4.3 3.6e-12 46.6 4.3 1.9 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 ORY18556.1 - 0.00016 21.5 0.0 0.079 12.8 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferase family 2 AAA_22 PF13401.6 ORY18556.1 - 0.014 15.7 0.1 0.048 13.9 0.1 1.9 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 ORY18556.1 - 0.083 13.3 0.1 0.2 12.0 0.1 1.6 1 0 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 ORY18556.1 - 0.084 12.8 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase Chitin_synth_2 PF03142.15 ORY18558.1 - 6.8e-231 767.4 0.0 1.1e-230 766.8 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Cyt-b5 PF00173.28 ORY18558.1 - 4.2e-14 52.4 0.0 1.6e-07 31.4 0.0 3.0 2 1 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_tranf_2_3 PF13641.6 ORY18558.1 - 2e-13 50.8 0.0 4.5e-13 49.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase like family 2 DEK_C PF08766.11 ORY18558.1 - 6e-13 48.5 0.5 3.2e-12 46.2 0.7 2.1 2 0 0 2 2 2 1 DEK C terminal domain Glyco_trans_2_3 PF13632.6 ORY18558.1 - 7.9e-13 48.8 2.0 7.9e-13 48.8 2.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 ORY18558.1 - 1.1e-05 25.0 0.1 8.8e-05 22.1 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 21 Myosin_head PF00063.21 ORY18558.1 - 0.00024 19.5 0.0 0.00037 18.9 0.0 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) Glycos_transf_2 PF00535.26 ORY18558.1 - 0.0053 16.6 0.0 0.12 12.2 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 2 End3 PF12761.7 ORY18559.1 - 2.3e-68 230.3 0.0 3e-68 229.9 0.0 1.1 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_4 PF12763.7 ORY18559.1 - 4e-48 161.7 0.0 2.8e-47 158.9 0.0 2.1 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 ORY18559.1 - 1.3e-08 33.8 0.5 6.2e-08 31.7 0.3 2.2 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 ORY18559.1 - 5.8e-07 29.9 0.2 1.9e-06 28.2 0.1 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 ORY18559.1 - 4.6e-05 23.2 0.3 0.00014 21.6 0.1 1.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 ORY18559.1 - 6.1e-05 22.6 0.3 0.00019 21.1 0.3 1.9 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.6 ORY18559.1 - 0.00049 19.5 0.1 0.0013 18.2 0.1 1.7 1 0 0 1 1 1 1 EF hand Med9 PF07544.13 ORY18559.1 - 0.037 14.1 2.0 0.065 13.3 0.0 2.3 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 MDMPI_N PF11716.8 ORY18559.1 - 0.05 14.3 1.3 0.62 10.7 1.3 2.7 1 1 0 1 1 1 0 Mycothiol maleylpyruvate isomerase N-terminal domain MtrG PF04210.13 ORY18559.1 - 0.11 12.4 0.1 24 4.8 0.0 2.6 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G Phage_GP20 PF06810.11 ORY18559.1 - 0.21 11.4 0.8 21 4.9 0.2 2.3 2 0 0 2 2 2 0 Phage minor structural protein GP20 TSC22 PF01166.18 ORY18559.1 - 0.23 11.8 6.0 4.4 7.7 0.4 2.5 2 0 0 2 2 2 0 TSC-22/dip/bun family DHR10 PF18595.1 ORY18559.1 - 0.37 10.8 7.9 0.68 10.0 2.3 2.3 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain SlyX PF04102.12 ORY18559.1 - 0.88 10.2 3.6 7.5 7.3 0.3 2.6 2 0 0 2 2 2 0 SlyX Csm1_N PF18504.1 ORY18559.1 - 4.8 7.6 6.6 19 5.7 1.5 2.9 2 1 0 2 2 2 0 Csm1 N-terminal domain LRR_8 PF13855.6 ORY18560.1 - 0.14 12.0 0.0 0.93 9.3 0.0 2.1 2 0 0 2 2 2 0 Leucine rich repeat Glyoxalase PF00903.25 ORY18561.1 - 0.0001 22.5 0.0 0.00011 22.3 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Cellulase PF00150.18 ORY18562.1 - 6.5e-43 147.2 0.0 8.1e-43 146.8 0.0 1.0 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Fungal_lectin PF07938.12 ORY18563.1 - 0.025 14.0 0.0 0.028 13.8 0.0 1.1 1 0 0 1 1 1 0 Fungal fucose-specific lectin Glyco_hydro_3 PF00933.21 ORY18564.1 - 1.5e-57 195.4 0.0 2.1e-57 194.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 ORY18564.1 - 1.3e-52 178.7 0.2 2.3e-52 177.9 0.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 ORY18564.1 - 5.1e-21 74.6 0.9 1.4e-20 73.2 0.9 1.8 1 0 0 1 1 1 1 Fibronectin type III-like domain Sugar-bind PF04198.13 ORY18564.1 - 0.043 12.9 0.0 0.099 11.8 0.0 1.5 1 0 0 1 1 1 0 Putative sugar-binding domain Sugar_tr PF00083.24 ORY18565.1 - 7.5e-94 315.1 27.3 8.8e-94 314.9 27.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY18565.1 - 1.7e-35 122.6 45.4 3.6e-30 105.1 25.7 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 ORY18565.1 - 0.0031 16.0 1.1 0.0031 16.0 1.1 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF3180 PF11377.8 ORY18565.1 - 0.77 9.9 6.4 0.46 10.6 0.3 3.4 2 1 2 4 4 4 0 Protein of unknown function (DUF3180) Glyco_hydro_31 PF01055.26 ORY18566.1 - 7.4e-104 348.4 2.9 9.1e-104 348.1 2.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 ORY18566.1 - 5e-12 46.0 0.0 1.3e-11 44.6 0.0 1.8 1 0 0 1 1 1 1 Galactose mutarotase-like Methyltransf_25 PF13649.6 ORY18567.1 - 8.7e-18 64.8 0.0 1.7e-17 63.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY18567.1 - 1.4e-16 60.9 0.0 3.2e-16 59.7 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORY18567.1 - 2.8e-12 46.5 0.0 8.6e-12 44.9 0.0 1.6 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 ORY18567.1 - 9.1e-11 41.8 0.0 1.2e-10 41.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY18567.1 - 1.5e-09 38.5 0.0 2.6e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY18567.1 - 3.8e-05 23.6 0.0 6.8e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ORY18567.1 - 0.00011 21.8 0.0 0.00018 21.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_8 PF05148.15 ORY18567.1 - 0.0055 16.6 0.0 0.12 12.2 0.0 2.2 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_5 PF01795.19 ORY18567.1 - 0.039 13.4 0.0 0.056 13.0 0.0 1.1 1 0 0 1 1 1 0 MraW methylase family PrmA PF06325.13 ORY18567.1 - 0.062 12.7 0.1 0.094 12.1 0.1 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.17 ORY18567.1 - 0.18 11.2 0.0 0.72 9.3 0.0 1.8 2 0 0 2 2 2 0 Putative methyltransferase EthD PF07110.11 ORY18568.1 - 2.8e-19 70.0 0.1 3.4e-19 69.8 0.1 1.1 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 ORY18568.1 - 0.0016 18.9 0.0 0.0027 18.1 0.0 1.4 1 1 0 1 1 1 1 Methylmuconolactone methyl-isomerase p450 PF00067.22 ORY18569.1 - 1.3e-63 215.4 0.0 1.6e-63 215.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 HET PF06985.11 ORY18570.1 - 4.3e-19 69.3 0.0 9.3e-19 68.2 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) EthD PF07110.11 ORY18573.1 - 4.4e-14 53.4 1.0 5.2e-14 53.2 1.0 1.1 1 0 0 1 1 1 1 EthD domain Cyclase PF04199.13 ORY18573.1 - 0.011 16.0 0.0 0.014 15.7 0.0 1.3 1 0 0 1 1 1 0 Putative cyclase DUF3830 PF12903.7 ORY18573.1 - 0.065 12.9 0.0 0.088 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3830) p450 PF00067.22 ORY18574.1 - 1.1e-27 96.9 0.0 3.7e-25 88.6 0.0 2.1 1 1 1 2 2 2 2 Cytochrome P450 adh_short PF00106.25 ORY18575.1 - 7.3e-20 71.3 0.0 7.7e-19 67.9 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY18575.1 - 1.7e-13 50.7 0.0 2.5e-12 46.9 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY18575.1 - 2.2e-05 24.4 0.0 3.6e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ORY18575.1 - 0.002 17.6 0.0 0.0026 17.3 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 ORY18575.1 - 0.0053 15.9 0.0 0.0076 15.4 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 ORY18575.1 - 0.04 13.3 0.0 0.057 12.8 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase LD_cluster2 PF18163.1 ORY18575.1 - 0.13 11.8 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 SLOG cluster2 Sacchrp_dh_NADP PF03435.18 ORY18575.1 - 0.14 12.4 0.0 0.23 11.7 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain UbiA PF01040.18 ORY18576.1 - 3.5e-19 69.1 3.3 4.5e-19 68.7 3.3 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family PDR_CDR PF06422.12 ORY18577.1 - 8.1e-17 60.9 0.1 9.3e-17 60.7 0.1 1.0 1 0 0 1 1 1 1 CDR ABC transporter KR PF08659.10 ORY18578.1 - 5.1e-25 88.4 0.2 2.8e-22 79.5 0.2 2.2 1 1 0 1 1 1 1 KR domain adh_short PF00106.25 ORY18578.1 - 0.062 12.7 0.0 0.076 12.5 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase YjeF_N PF03853.15 ORY18578.1 - 0.096 12.6 0.1 0.2 11.6 0.1 1.6 1 1 0 1 1 1 0 YjeF-related protein N-terminus PP-binding PF00550.25 ORY18579.1 - 5.2e-07 29.9 0.0 7.1e-07 29.5 0.0 1.3 1 1 0 1 1 1 1 Phosphopantetheine attachment site CaATP_NAI PF12515.8 ORY18579.1 - 0.14 11.8 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Ca2+-ATPase N terminal autoinhibitory domain GATA PF00320.27 ORY18581.1 - 4.9e-15 54.8 3.2 8.4e-15 54.1 3.2 1.4 1 0 0 1 1 1 1 GATA zinc finger Macoilin PF09726.9 ORY18581.1 - 0.016 13.8 0.2 0.016 13.8 0.2 1.1 1 0 0 1 1 1 0 Macoilin family Atg14 PF10186.9 ORY18581.1 - 0.055 12.6 3.5 0.095 11.8 3.5 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TF_Zn_Ribbon PF08271.12 ORY18581.1 - 0.061 12.8 0.7 0.11 12.0 0.7 1.4 1 0 0 1 1 1 0 TFIIB zinc-binding Auto_anti-p27 PF06677.12 ORY18581.1 - 0.31 11.2 0.9 0.53 10.5 0.9 1.3 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Pox_A_type_inc PF04508.12 ORY18581.1 - 4.7 7.2 9.7 10 6.1 0.1 3.4 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat SRP68 PF16969.5 ORY18583.1 - 2.7e-184 614.3 0.4 3e-184 614.1 0.4 1.0 1 0 0 1 1 1 1 RNA-binding signal recognition particle 68 TPR_1 PF00515.28 ORY18583.1 - 0.023 14.5 0.1 0.073 12.9 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat PPR_2 PF13041.6 ORY18584.1 - 2.9e-26 91.4 0.6 9.2e-09 35.4 0.0 6.2 7 0 0 7 7 7 3 PPR repeat family PPR PF01535.20 ORY18584.1 - 1e-17 63.1 5.8 5.4e-05 23.2 0.1 9.4 10 0 0 10 10 10 3 PPR repeat PPR_3 PF13812.6 ORY18584.1 - 1.2e-08 34.8 0.0 0.00081 19.4 0.0 4.6 4 1 2 6 6 6 2 Pentatricopeptide repeat domain PPR_long PF17177.4 ORY18584.1 - 2.4e-08 33.6 0.0 0.00028 20.3 0.0 3.5 1 1 3 4 4 4 4 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 ORY18584.1 - 4.4e-07 29.5 0.8 0.0028 17.3 0.1 4.5 4 0 0 4 4 4 2 PPR repeat TPR_14 PF13428.6 ORY18584.1 - 3.7e-06 27.3 8.3 27 5.9 0.1 8.8 10 1 1 11 11 11 0 Tetratricopeptide repeat TPR_19 PF14559.6 ORY18584.1 - 0.00037 20.9 0.8 4.9 7.7 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_4 PF07721.14 ORY18584.1 - 0.051 14.2 0.2 20 6.2 0.0 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Serinc PF03348.15 ORY18587.1 - 1.4e-159 531.6 10.3 1.6e-159 531.4 10.3 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) MFS_1 PF07690.16 ORY18588.1 - 1.2e-10 40.9 26.5 1.5e-06 27.4 11.6 2.7 2 1 1 3 3 3 2 Major Facilitator Superfamily Nodulin-like PF06813.13 ORY18588.1 - 2.3e-07 30.6 10.9 7.9e-07 28.8 4.4 2.7 2 1 1 3 3 3 2 Nodulin-like WBP-1 PF11669.8 ORY18588.1 - 0.21 12.2 1.3 2.2 9.0 0.3 2.5 2 0 0 2 2 2 0 WW domain-binding protein 1 MMS1_N PF10433.9 ORY18589.1 - 4.6e-64 216.8 0.0 6.7e-64 216.3 0.0 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term RabGAP-TBC PF00566.18 ORY18590.1 - 4.1e-22 78.9 0.0 5.6e-22 78.4 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain HET PF06985.11 ORY18591.1 - 5.9e-33 114.3 1.7 1e-32 113.5 1.7 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) TMEM252 PF15664.5 ORY18591.1 - 0.18 11.5 0.5 0.37 10.5 0.5 1.5 1 0 0 1 1 1 0 Transmembrane protein 252 family Trimer_CC PF08954.11 ORY18595.1 - 0.049 13.2 0.1 0.1 12.2 0.1 1.6 1 0 0 1 1 1 0 Trimerisation motif Propeptide_C25 PF08126.11 ORY18595.1 - 0.079 12.0 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Propeptide_C25 Yae1_N PF09811.9 ORY18596.1 - 0.036 13.8 0.8 0.083 12.6 0.8 1.6 1 0 0 1 1 1 0 Essential protein Yae1, N terminal adh_short_C2 PF13561.6 ORY18597.1 - 8.2e-53 179.4 1.5 1.4e-52 178.6 1.5 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY18597.1 - 4.6e-52 176.3 0.7 5.6e-52 176.0 0.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORY18597.1 - 5.7e-10 39.4 0.2 1.1e-09 38.5 0.2 1.6 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 ORY18597.1 - 0.0086 15.6 0.2 0.017 14.6 0.2 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family HHH_5 PF14520.6 ORY18597.1 - 0.11 13.2 1.9 1.6 9.4 0.2 3.2 3 1 1 4 4 4 0 Helix-hairpin-helix domain DASH_Ask1 PF08655.10 ORY18598.1 - 1.7e-28 98.2 0.1 2.8e-28 97.6 0.1 1.4 1 0 0 1 1 1 1 DASH complex subunit Ask1 PI3_PI4_kinase PF00454.27 ORY18599.1 - 5.8e-43 147.5 0.0 8.4e-43 147.0 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase CiPC PF15800.5 ORY18599.1 - 3.4 7.3 10.1 0.18 11.5 4.3 1.7 2 0 0 2 2 2 0 Clock interacting protein circadian SNF2_N PF00176.23 ORY18600.1 - 1.1e-70 238.2 0.3 1.6e-70 237.6 0.3 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ORY18600.1 - 1.3e-13 51.2 0.0 2.3e-12 47.2 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 ORY18600.1 - 2.3e-05 24.3 0.0 5.4e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 ORY18600.1 - 0.00014 22.0 0.1 0.00033 20.7 0.1 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-RING_5 PF14634.6 ORY18600.1 - 0.00023 21.0 1.8 0.00046 20.1 1.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain HIRAN PF08797.11 ORY18600.1 - 0.0082 16.0 0.0 0.037 14.0 0.0 2.0 2 0 0 2 2 2 1 HIRAN domain ERCC3_RAD25_C PF16203.5 ORY18600.1 - 0.096 11.9 0.1 0.31 10.2 0.0 1.9 2 0 0 2 2 2 0 ERCC3/RAD25/XPB C-terminal helicase Exo_endo_phos PF03372.23 ORY18601.1 - 1.3e-05 24.9 0.1 4.3e-05 23.2 0.1 1.9 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family MFS_1 PF07690.16 ORY18602.1 - 1.2e-33 116.5 29.4 2.3e-33 115.6 29.4 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF4795 PF16043.5 ORY18603.1 - 0.0019 17.9 0.2 0.0022 17.7 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4795) DUF1640 PF07798.11 ORY18603.1 - 0.055 13.5 3.3 0.063 13.3 3.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) DUF573 PF04504.14 ORY18603.1 - 0.06 14.0 3.4 0.83 10.4 1.3 2.3 1 1 1 2 2 2 0 Protein of unknown function, DUF573 FapA PF03961.13 ORY18603.1 - 0.2 10.2 3.4 0.24 9.9 3.4 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A Sec2p PF06428.11 ORY18604.1 - 0.00022 21.2 1.6 0.32 11.0 0.2 2.3 2 0 0 2 2 2 2 GDP/GTP exchange factor Sec2p Laminin_II PF06009.12 ORY18604.1 - 0.025 14.6 0.1 4 7.5 0.0 2.1 2 0 0 2 2 2 0 Laminin Domain II BST2 PF16716.5 ORY18604.1 - 0.072 13.7 1.4 0.25 11.9 0.1 2.1 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 Jnk-SapK_ap_N PF09744.9 ORY18604.1 - 1.1 9.5 6.0 1.5 9.1 3.9 1.9 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 DUF2034 PF10356.9 ORY18606.1 - 1.5e-29 102.7 0.0 1.9e-18 66.5 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF2034) Mrr_cat PF04471.12 ORY18606.1 - 3.3e-08 33.5 0.0 5.6e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Restriction endonuclease Med21 PF11221.8 ORY18607.1 - 1.2e-39 135.9 8.5 1.7e-39 135.4 8.5 1.1 1 0 0 1 1 1 1 Subunit 21 of Mediator complex AIP3 PF03915.13 ORY18607.1 - 0.00082 18.6 3.5 0.0009 18.4 3.5 1.0 1 0 0 1 1 1 1 Actin interacting protein 3 DUF948 PF06103.11 ORY18607.1 - 0.012 15.9 4.7 0.15 12.3 0.1 3.0 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) AAA_23 PF13476.6 ORY18607.1 - 0.025 15.1 2.1 0.031 14.8 2.1 1.1 1 0 0 1 1 1 0 AAA domain STAT_alpha PF01017.20 ORY18607.1 - 0.042 13.8 5.9 7.6 6.4 0.1 2.1 1 1 1 2 2 2 0 STAT protein, all-alpha domain DUF3450 PF11932.8 ORY18607.1 - 0.069 12.4 12.7 0.013 14.8 7.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Herpes_UL6 PF01763.16 ORY18607.1 - 0.079 11.5 3.2 0.1 11.1 3.2 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like ALIX_LYPXL_bnd PF13949.6 ORY18607.1 - 0.11 11.8 8.7 0.015 14.6 5.2 1.4 2 0 0 2 2 2 0 ALIX V-shaped domain binding to HIV Spore_III_AB PF09548.10 ORY18607.1 - 0.21 11.7 4.3 0.26 11.4 4.3 1.4 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) DUF1664 PF07889.12 ORY18607.1 - 0.26 11.3 4.7 0.11 12.6 1.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF737 PF05300.11 ORY18607.1 - 0.26 11.6 7.3 0.36 11.2 7.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF737) Med9 PF07544.13 ORY18607.1 - 0.33 11.1 6.6 0.14 12.3 3.1 2.2 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Med26_C PF15693.5 ORY18607.1 - 0.33 11.1 5.0 0.41 10.8 5.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 26 C-terminal ATG16 PF08614.11 ORY18607.1 - 0.37 11.0 15.3 0.8 9.9 15.3 1.5 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) SlyX PF04102.12 ORY18607.1 - 0.37 11.4 9.3 2.6 8.8 0.0 3.2 2 1 0 2 2 2 0 SlyX Seryl_tRNA_N PF02403.22 ORY18607.1 - 3.4 7.9 10.3 1.3 9.3 2.2 2.5 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DivIC PF04977.15 ORY18607.1 - 6.9 6.5 7.9 2.6 7.9 2.6 2.3 2 0 0 2 2 2 0 Septum formation initiator Peptidase_C2 PF00648.21 ORY18608.1 - 1.4e-64 218.0 4.4 1.5e-63 214.6 3.8 2.6 2 1 0 2 2 2 1 Calpain family cysteine protease EccE PF11203.8 ORY18608.1 - 0.066 13.5 1.1 0.12 12.7 0.0 2.0 2 0 0 2 2 2 0 Putative type VII ESX secretion system translocon, EccE C1_2 PF03107.16 ORY18610.1 - 0.0034 17.7 9.3 0.0041 17.4 9.3 1.2 1 0 0 1 1 1 1 C1 domain zf-HIT PF04438.16 ORY18610.1 - 0.023 14.6 6.8 0.051 13.5 6.8 1.5 1 0 0 1 1 1 0 HIT zinc finger Zn-ribbon_8 PF09723.10 ORY18610.1 - 3.7 7.8 9.2 6.3 7.0 1.0 2.6 2 1 0 2 2 2 0 Zinc ribbon domain Acetyltransf_4 PF13420.7 ORY18612.1 - 3.4e-09 37.0 0.0 1.6e-08 34.8 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORY18612.1 - 7.5e-07 29.4 0.0 1.2e-06 28.7 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ORY18612.1 - 6.8e-05 23.2 0.1 0.00015 22.1 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ORY18612.1 - 0.0035 17.3 0.0 0.28 11.1 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 ORY18612.1 - 0.037 14.7 0.0 0.047 14.4 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF2977 PF11192.8 ORY18612.1 - 0.04 14.1 0.0 0.071 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2977) Pribosyl_synth PF14572.6 ORY18613.1 - 1.6e-32 113.0 0.0 5.3e-26 91.8 0.0 2.3 2 0 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 ORY18613.1 - 2.4e-25 88.7 0.4 9.7e-14 51.3 0.2 4.3 2 1 1 3 3 3 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 ORY18613.1 - 7.4e-06 25.6 0.5 0.0025 17.4 0.1 2.8 3 0 0 3 3 3 2 Phosphoribosyl transferase domain UBM PF14377.6 ORY18613.1 - 0.078 12.5 0.2 0.16 11.5 0.2 1.5 1 0 0 1 1 1 0 Ubiquitin binding region Ank_2 PF12796.7 ORY18614.1 - 4.4e-24 84.9 0.0 6.8e-08 33.0 0.0 4.5 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY18614.1 - 5.2e-21 74.7 0.6 0.00029 21.3 0.0 7.5 4 1 4 8 8 8 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 ORY18614.1 - 1.4e-19 69.8 1.5 1.1e-08 35.2 0.8 5.3 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY18614.1 - 1.1e-16 59.2 0.0 0.061 13.9 0.1 8.3 8 0 0 8 8 8 3 Ankyrin repeat Ank PF00023.30 ORY18614.1 - 4.8e-07 29.9 0.1 0.69 10.5 0.0 6.3 8 0 0 8 8 8 2 Ankyrin repeat Autophagy_act_C PF03987.15 ORY18614.1 - 0.0075 16.8 0.1 0.021 15.4 0.1 1.7 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Zn_clus PF00172.18 ORY18614.1 - 2.3 8.4 11.6 0.65 10.2 8.6 1.7 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Cortex-I_coil PF09304.10 ORY18615.1 - 0.0073 16.5 7.0 0.14 12.4 0.4 2.7 1 1 1 2 2 2 1 Cortexillin I, coiled coil Pex19 PF04614.12 ORY18615.1 - 0.0079 16.0 9.9 0.7 9.6 5.5 2.5 1 1 2 3 3 3 2 Pex19 protein family RabGAP-TBC PF00566.18 ORY18615.1 - 0.012 15.2 0.1 54 3.3 0.0 4.4 2 2 2 4 4 4 0 Rab-GTPase-TBC domain HEPN_Toprim_N PF18871.1 ORY18615.1 - 0.036 14.0 7.4 12 5.8 0.6 4.3 1 1 2 4 4 4 0 HEPN/Toprim N-terminal domain 1 DUF3632 PF12311.8 ORY18615.1 - 0.2 12.1 6.6 36 4.7 4.1 3.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3632) Reprolysin_4 PF13583.6 ORY18615.1 - 0.2 11.2 11.8 0.035 13.7 2.6 2.4 1 1 1 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like DUF4192 PF13830.6 ORY18615.1 - 0.4 10.7 28.8 0.14 12.2 3.5 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4192) T2SSF PF00482.23 ORY18615.1 - 0.47 10.4 3.7 15 5.6 0.2 2.7 1 1 1 2 2 2 0 Type II secretion system (T2SS), protein F GET2 PF08690.10 ORY18615.1 - 0.57 9.8 5.8 3.1 7.4 5.8 2.0 1 1 0 1 1 1 0 GET complex subunit GET2 FCD PF07729.12 ORY18615.1 - 0.59 10.6 27.9 13 6.2 0.2 5.8 2 2 4 6 6 6 0 FCD domain BLUF PF04940.12 ORY18615.1 - 0.62 10.2 5.6 1.4e+02 2.7 0.1 5.0 1 1 5 6 6 6 0 Sensors of blue-light using FAD PqqD PF05402.12 ORY18615.1 - 0.8 10.0 7.6 1.9 8.8 0.5 3.9 2 1 3 5 5 5 0 Coenzyme PQQ synthesis protein D (PqqD) Phage-MuB_C PF09077.11 ORY18615.1 - 0.92 9.4 8.6 3.9 7.4 0.9 3.6 1 1 3 4 4 4 0 Mu B transposition protein, C terminal DUF5578 PF17741.1 ORY18615.1 - 1.1 8.6 2.9 41 3.5 0.0 4.0 1 1 5 6 6 6 0 Family of unknown function (DUF5578) Formyl_trans_N PF00551.19 ORY18615.1 - 1.9 8.2 4.1 11 5.7 0.2 2.1 1 1 1 2 2 2 0 Formyl transferase Wzy_C_2 PF11846.8 ORY18615.1 - 2.2 8.2 5.3 1 9.2 0.8 2.4 1 1 0 2 2 2 0 Virulence factor membrane-bound polymerase, C-terminal LPD22 PF18834.1 ORY18615.1 - 5.2 7.4 36.2 10 6.4 0.6 5.7 1 1 2 4 4 4 0 Large polyvalent protein associated domain 22 ATP-synt_C PF00137.21 ORY18617.1 - 1e-12 48.2 10.1 1e-12 48.2 10.1 2.4 2 1 1 3 3 3 1 ATP synthase subunit C Baculo_p74 PF04583.12 ORY18617.1 - 0.17 11.3 1.2 0.23 10.9 1.2 1.1 1 0 0 1 1 1 0 Baculoviridae p74 conserved region Peptidase_S8 PF00082.22 ORY18618.1 - 2.1e-13 50.2 0.9 4.8e-13 49.0 0.2 1.8 1 1 0 2 2 2 1 Subtilase family PCB_OB PF17092.5 ORY18618.1 - 0.029 15.1 0.1 0.17 12.6 0.0 2.1 2 0 0 2 2 2 0 Penicillin-binding protein OB-like domain N_BRCA1_IG PF16158.5 ORY18621.1 - 0.099 13.4 0.0 16 6.3 0.0 2.6 2 0 0 2 2 2 0 Ig-like domain from next to BRCA1 gene Kisspeptin PF15152.6 ORY18623.1 - 0.67 10.8 3.0 0.64 10.8 0.9 2.0 1 1 0 1 1 1 0 Kisspeptin LPD1 PF18796.1 ORY18624.1 - 1.2 9.3 3.2 1.6 8.9 0.2 2.4 3 0 0 3 3 3 0 Large polyvalent protein-associated domain 1 Ank_2 PF12796.7 ORY18625.1 - 1.7e-21 76.6 0.0 5.9e-11 42.8 0.0 3.6 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY18625.1 - 1e-19 70.6 0.0 8.1e-07 29.5 0.0 5.0 4 1 0 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 ORY18625.1 - 9.5e-15 54.5 0.0 0.00074 19.8 0.0 4.9 3 1 3 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY18625.1 - 1.5e-08 34.2 0.3 0.11 13.1 0.0 6.4 7 0 0 7 7 7 2 Ankyrin repeat Ank PF00023.30 ORY18625.1 - 9.5e-07 29.0 0.3 0.12 12.8 0.0 4.6 4 1 0 4 4 4 2 Ankyrin repeat Zn_clus PF00172.18 ORY18625.1 - 0.25 11.5 11.2 0.76 9.9 11.2 1.8 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1996 PF09362.10 ORY18626.1 - 1.3e-82 277.3 0.8 1.8e-82 276.8 0.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) TRI12 PF06609.13 ORY18627.1 - 1.4e-41 142.6 20.1 1.9e-41 142.2 20.1 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 ORY18627.1 - 6.7e-22 77.9 51.4 1.7e-21 76.6 49.1 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY18627.1 - 7.1e-11 41.6 11.3 7.1e-11 41.6 11.3 3.1 3 0 0 3 3 3 1 Sugar (and other) transporter p450 PF00067.22 ORY18628.1 - 5.2e-64 216.7 0.0 6.4e-64 216.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_61 PF03443.14 ORY18629.1 - 3.2e-51 174.2 0.0 4e-51 173.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 MG2 PF01835.19 ORY18629.1 - 0.02 15.4 0.0 0.038 14.4 0.0 1.6 1 0 0 1 1 1 0 MG2 domain Zn_clus PF00172.18 ORY18630.1 - 8.2e-08 32.2 12.1 1.4e-07 31.5 12.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 ORY18630.1 - 0.00043 19.2 0.2 0.00068 18.5 0.2 1.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain Beta-lactamase PF00144.24 ORY18631.1 - 4.4e-25 88.6 0.0 6.5e-25 88.1 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase HSP70 PF00012.20 ORY18632.1 - 0.00092 17.5 0.0 0.16 10.1 0.0 2.4 3 0 0 3 3 3 2 Hsp70 protein AIG1 PF04548.16 ORY18633.1 - 5.7e-11 42.2 0.0 1e-10 41.3 0.0 1.4 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.23 ORY18633.1 - 8.5e-08 32.3 0.0 2.5e-07 30.8 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase Septin PF00735.18 ORY18633.1 - 3.1e-05 23.4 0.0 6.8e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Septin RsgA_GTPase PF03193.16 ORY18633.1 - 0.00016 21.6 0.1 0.0004 20.3 0.1 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 ORY18633.1 - 0.00026 21.3 0.1 0.0014 18.9 0.0 2.2 2 2 0 2 2 2 1 AAA domain SRPRB PF09439.10 ORY18633.1 - 0.00039 19.9 1.2 0.0011 18.4 0.0 2.1 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Dynamin_N PF00350.23 ORY18633.1 - 0.00092 19.3 3.4 0.17 12.0 0.0 3.0 2 1 1 3 3 3 2 Dynamin family AAA_16 PF13191.6 ORY18633.1 - 0.028 14.8 0.1 0.11 12.9 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain GBP PF02263.19 ORY18633.1 - 0.043 13.1 0.0 0.076 12.3 0.0 1.3 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain AAA_33 PF13671.6 ORY18633.1 - 0.054 13.7 1.2 0.065 13.4 0.1 2.0 2 1 0 2 2 2 0 AAA domain Peptidase_C50 PF03568.17 ORY18633.1 - 0.065 12.3 2.1 0.11 11.6 2.1 1.3 1 0 0 1 1 1 0 Peptidase family C50 DUF87 PF01935.17 ORY18633.1 - 2.6 8.1 6.2 0.54 10.3 0.2 2.3 2 1 0 2 2 2 0 Helicase HerA, central domain ATG16 PF08614.11 ORY18634.1 - 0.25 11.5 32.1 2.7 8.2 14.4 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Exonuc_VII_L PF02601.15 ORY18634.1 - 0.7 9.4 15.8 1 8.8 15.8 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Atg14 PF10186.9 ORY18634.1 - 2.3 7.2 29.7 0.14 11.3 14.6 2.0 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Spc7 PF08317.11 ORY18634.1 - 2.5 6.9 27.9 0.085 11.7 15.4 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein FAM76 PF16046.5 ORY18634.1 - 2.6 7.3 24.7 0.29 10.5 16.5 2.1 1 1 1 2 2 2 0 FAM76 protein HSP70 PF00012.20 ORY18634.1 - 9.4 4.3 14.4 15 3.6 14.4 1.2 1 0 0 1 1 1 0 Hsp70 protein CorA PF01544.18 ORY18635.1 - 0.092 12.1 10.2 0.043 13.1 3.1 2.9 2 1 0 2 2 2 0 CorA-like Mg2+ transporter protein Lactamase_B PF00753.27 ORY18637.1 - 3.7e-16 59.7 2.3 2.2e-15 57.2 2.3 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 ORY18637.1 - 0.00044 19.8 0.1 0.0007 19.2 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain GSH_synth_ATP PF03917.17 ORY18637.1 - 0.043 12.6 0.0 0.056 12.2 0.0 1.1 1 0 0 1 1 1 0 Eukaryotic glutathione synthase, ATP binding domain UPF0489 PF12640.7 ORY18637.1 - 0.081 13.2 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 UPF0489 domain Sulf_transp PF04143.14 ORY18638.1 - 1.4e-35 123.4 17.9 2.3e-35 122.7 17.9 1.4 1 1 0 1 1 1 1 Sulphur transport Sulfate_transp PF00916.20 ORY18639.1 - 3.8e-103 345.2 18.4 4.8e-103 344.8 18.4 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 ORY18639.1 - 2.1e-09 37.0 0.0 4.1e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 STAS domain DUF3636 PF12331.8 ORY18641.1 - 2.7e-42 144.1 0.4 5.2e-42 143.2 0.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3636) LCD1 PF09798.9 ORY18641.1 - 0.0023 16.5 1.5 0.29 9.6 0.0 2.5 2 1 1 3 3 3 2 DNA damage checkpoint protein FAM76 PF16046.5 ORY18641.1 - 0.012 15.0 0.6 0.022 14.2 0.6 1.3 1 0 0 1 1 1 0 FAM76 protein DUF3136 PF11334.8 ORY18641.1 - 0.039 13.7 0.0 0.12 12.2 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3136) CTP_transf_1 PF01148.20 ORY18642.1 - 1.9e-82 277.0 23.7 2.5e-82 276.7 23.7 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family PPR_2 PF13041.6 ORY18643.1 - 1.5e-18 66.7 0.0 0.021 15.0 0.0 8.2 6 3 3 9 9 9 5 PPR repeat family PPR_3 PF13812.6 ORY18643.1 - 1e-15 57.6 0.0 0.0011 19.0 0.0 6.4 5 1 1 6 6 6 4 Pentatricopeptide repeat domain PPR_long PF17177.4 ORY18643.1 - 2.3e-09 36.9 0.0 0.016 14.6 0.0 4.4 3 1 2 5 5 5 2 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 ORY18643.1 - 8.2e-09 35.1 2.4 0.0093 16.2 0.1 7.4 7 0 0 7 7 7 1 PPR repeat PPR_1 PF12854.7 ORY18643.1 - 9.8e-05 22.0 0.5 0.068 12.9 0.0 4.5 5 0 0 5 5 5 1 PPR repeat AAA PF00004.29 ORY18644.1 - 1.9e-16 60.7 0.0 4.5e-16 59.5 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 ORY18644.1 - 0.0013 18.7 0.0 0.0033 17.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 ORY18644.1 - 0.0021 18.5 0.1 0.0021 18.5 0.1 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_2 PF07724.14 ORY18644.1 - 0.0033 17.5 0.0 0.0033 17.5 0.0 2.2 2 1 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 ORY18644.1 - 0.0036 17.6 0.2 0.028 14.7 0.1 2.4 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 ORY18644.1 - 0.0097 15.7 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Cyc-maltodext_N PF09087.11 ORY18644.1 - 0.041 14.2 0.3 0.12 12.6 0.3 1.8 1 0 0 1 1 1 0 Cyclomaltodextrinase, N-terminal Mg_chelatase PF01078.21 ORY18644.1 - 0.11 11.9 0.2 0.36 10.2 0.1 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 ORY18644.1 - 0.13 12.4 0.0 0.13 12.4 0.0 2.2 3 0 0 3 3 1 0 AAA domain AAA_18 PF13238.6 ORY18644.1 - 0.16 12.5 0.0 0.16 12.5 0.0 2.9 3 1 0 3 3 2 0 AAA domain Rab_eff_C PF04698.12 ORY18644.1 - 2.7 6.2 35.5 4 5.6 35.5 1.2 1 0 0 1 1 1 0 Rab effector MyRIP/melanophilin C-terminus DSPc PF00782.20 ORY18645.1 - 6.9e-10 38.9 0.0 1.2e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 ORY18645.1 - 0.00092 18.8 0.0 0.0018 17.9 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 ORY18645.1 - 0.0069 16.5 0.0 0.014 15.5 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate CDKN3 PF05706.12 ORY18645.1 - 0.0092 15.7 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase3 PF13350.6 ORY18645.1 - 0.037 14.0 0.0 0.06 13.3 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family Fungal_trans PF04082.18 ORY18646.1 - 7.9e-19 67.7 0.1 1.2e-18 67.1 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY18646.1 - 1.2e-07 31.7 10.9 2.7e-07 30.6 10.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TniQ PF06527.11 ORY18646.1 - 0.068 13.9 0.0 0.068 13.9 0.0 2.4 3 1 0 3 3 3 0 TniQ DUF1479 PF07350.12 ORY18648.1 - 0.068 11.9 0.0 0.093 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1479) Sugar_tr PF00083.24 ORY18649.1 - 8e-34 117.3 13.1 6.6e-24 84.6 0.4 2.4 2 1 1 3 3 3 2 Sugar (and other) transporter DUF778 PF05608.12 ORY18650.1 - 0.0025 18.2 0.1 0.014 15.8 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF778) Peptidase_C97 PF05903.14 ORY18650.1 - 0.0035 17.2 0.0 0.0059 16.4 0.0 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain DUF4105 PF13387.6 ORY18650.1 - 0.033 13.8 0.0 0.048 13.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4105) LRAT PF04970.13 ORY18650.1 - 0.15 12.4 0.3 2 8.7 0.3 2.5 1 1 0 1 1 1 0 Lecithin retinol acyltransferase DUF4796 PF16044.5 ORY18650.1 - 0.17 11.4 0.1 0.37 10.4 0.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4796) Bul1_C PF04426.12 ORY18652.1 - 0.015 14.7 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 Bul1 C terminus OSCP PF00213.18 ORY18674.1 - 2.3e-46 158.1 0.0 3.3e-46 157.6 0.0 1.2 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit UPF0257 PF06788.13 ORY18674.1 - 0.2 11.5 0.0 0.32 10.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0257) Metal_resist PF13801.6 ORY18675.1 - 0.26 11.5 4.9 11 6.3 1.3 2.9 3 0 0 3 3 3 0 Heavy-metal resistance CLN3 PF02487.17 ORY18676.1 - 6.5e-160 532.5 4.0 7.4e-160 532.4 4.0 1.0 1 0 0 1 1 1 1 CLN3 protein Rxt3 PF08642.10 ORY18677.1 - 5e-31 108.1 0.0 5e-31 108.1 0.0 2.2 3 0 0 3 3 3 1 Histone deacetylation protein Rxt3 LCCL PF03815.19 ORY18677.1 - 1.5e-05 25.0 0.0 0.00036 20.6 0.0 2.3 2 0 0 2 2 2 1 LCCL domain SelP_N PF04592.14 ORY18677.1 - 0.41 10.0 13.7 1.1 8.6 13.7 1.7 1 0 0 1 1 1 0 Selenoprotein P, N terminal region 6PF2K PF01591.18 ORY18679.1 - 7.9e-82 273.9 0.0 1.1e-81 273.3 0.0 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 ORY18679.1 - 4.3e-35 121.2 0.0 6.7e-35 120.6 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 ORY18679.1 - 3.8e-05 23.9 0.0 8.3e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 ORY18679.1 - 0.0027 17.2 0.1 0.0045 16.5 0.1 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 Diphthamide_syn PF01866.17 ORY18682.1 - 2.5e-108 362.1 0.0 3.2e-108 361.8 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein MFS_1 PF07690.16 ORY18683.1 - 1.9e-44 152.1 28.5 1.9e-44 152.1 28.5 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY18683.1 - 3.3e-09 36.1 10.1 3.3e-09 36.1 10.1 2.6 3 1 0 3 3 3 1 Sugar (and other) transporter MFS_4 PF06779.14 ORY18683.1 - 4.2e-06 26.3 2.7 4.2e-06 26.3 2.7 2.5 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB RRM_1 PF00076.22 ORY18685.1 - 7.8e-08 32.0 0.0 1.5e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1687 PF07955.11 ORY18686.1 - 2e-28 99.4 0.0 2.7e-28 99.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1687) Ribosomal_S30 PF04758.14 ORY18687.1 - 1.4e-29 102.1 8.5 1.5e-29 102.0 8.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 Pyrid_oxidase_2 PF13883.6 ORY18688.1 - 6.6e-47 159.6 0.0 8.2e-47 159.3 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase zf-C2H2 PF00096.26 ORY18689.1 - 1.8e-09 37.6 10.3 0.00032 21.0 1.2 3.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY18689.1 - 1.7e-05 25.0 1.0 1.7e-05 25.0 1.0 3.7 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_6 PF13912.6 ORY18689.1 - 0.013 15.4 0.9 0.013 15.4 0.9 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_4 PF13894.6 ORY18689.1 - 0.12 13.2 1.1 0.11 13.4 1.8 3.8 4 0 0 4 4 4 0 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 ORY18689.1 - 0.37 10.9 2.4 5.2 7.3 0.3 2.4 1 1 1 2 2 2 0 Zinc ribbon domain Zn_ribbon_SprT PF17283.2 ORY18689.1 - 0.57 10.1 6.5 0.38 10.7 1.6 2.4 1 1 1 2 2 2 0 SprT-like zinc ribbon domain Rpr2 PF04032.16 ORY18689.1 - 3.2 8.1 7.9 0.16 12.3 0.6 2.5 3 0 0 3 3 3 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-met PF12874.7 ORY18689.1 - 3.6 8.1 13.4 0.083 13.3 1.8 3.8 4 0 0 4 4 4 0 Zinc-finger of C2H2 type GDI PF00996.18 ORY18694.1 - 6.4e-26 90.9 0.0 2.3e-24 85.7 0.0 2.2 1 1 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.6 ORY18694.1 - 0.069 13.4 0.0 0.17 12.1 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Redoxin PF08534.10 ORY18695.1 - 1.5e-38 131.8 0.0 1.7e-38 131.6 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 ORY18695.1 - 6.2e-11 42.3 0.0 6.4e-11 42.2 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family DUF1348 PF07080.11 ORY18696.1 - 9.9e-60 200.2 8.3 1.2e-59 199.9 8.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) SnoaL_2 PF12680.7 ORY18696.1 - 1.6e-06 28.7 0.3 2.1e-06 28.3 0.3 1.3 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 ORY18696.1 - 0.00093 19.6 0.1 0.0019 18.6 0.1 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4440) Robl_LC7 PF03259.17 ORY18697.1 - 5.7e-10 38.8 0.0 1.3e-06 28.1 0.0 2.1 2 0 0 2 2 2 2 Roadblock/LC7 domain Ipi1_N PF12333.8 ORY18698.1 - 3.1e-25 88.7 1.1 9.7e-25 87.1 0.0 2.3 2 1 0 2 2 2 1 Rix1 complex component involved in 60S ribosome maturation DUF262 PF03235.14 ORY18699.1 - 7e-16 59.1 0.0 1.4e-15 58.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function DUF262 adh_short PF00106.25 ORY18700.1 - 2.3e-26 92.5 0.0 6e-25 87.9 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY18700.1 - 2.6e-13 50.1 0.0 5.2e-12 45.8 0.0 2.5 2 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY18700.1 - 3.1e-10 40.3 0.0 4.5e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ORY18700.1 - 0.00021 20.8 0.0 0.00029 20.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 ORY18700.1 - 0.047 12.8 0.0 0.065 12.4 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein His_Phos_2 PF00328.22 ORY18701.1 - 3.2e-41 142.0 0.0 3.8e-41 141.7 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PND PF17949.1 ORY18701.1 - 0.2 11.9 0.1 1.7 8.9 0.0 2.3 3 0 0 3 3 3 0 FANCM pseudonuclease domain FMN_dh PF01070.18 ORY18702.1 - 4.9e-117 390.8 0.0 6.3e-117 390.5 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase ThiG PF05690.14 ORY18702.1 - 3.3e-05 23.3 0.1 0.075 12.3 0.1 2.3 1 1 0 2 2 2 2 Thiazole biosynthesis protein ThiG IMPDH PF00478.25 ORY18702.1 - 8.8e-05 21.6 0.7 0.00019 20.5 0.7 1.6 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 ORY18702.1 - 0.00021 20.5 0.2 0.00033 19.9 0.2 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.15 ORY18702.1 - 0.0048 16.3 0.2 0.0067 15.8 0.2 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase His_biosynth PF00977.21 ORY18702.1 - 0.0072 15.8 0.3 0.66 9.4 0.0 2.5 1 1 1 2 2 2 1 Histidine biosynthesis protein IGPS PF00218.21 ORY18702.1 - 0.055 12.6 0.1 0.21 10.7 0.1 1.8 1 1 0 1 1 1 0 Indole-3-glycerol phosphate synthase HATPase_c PF02518.26 ORY18703.1 - 3.9e-22 78.9 0.0 9e-22 77.7 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 ORY18703.1 - 9.9e-19 67.6 0.1 1.1e-16 61.0 0.1 2.9 1 1 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 ORY18703.1 - 4.5e-09 36.2 0.6 3.6e-07 30.1 0.0 2.9 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_4 PF08448.10 ORY18703.1 - 6e-09 36.1 0.5 0.00043 20.5 0.0 4.3 3 1 1 4 4 4 2 PAS fold PAS_3 PF08447.12 ORY18703.1 - 0.00071 19.8 0.1 0.0083 16.4 0.0 2.7 1 1 1 2 2 2 1 PAS fold PAS PF00989.25 ORY18703.1 - 0.001 19.1 0.0 0.0028 17.6 0.0 1.8 1 0 0 1 1 1 1 PAS fold HATPase_c_3 PF13589.6 ORY18703.1 - 0.016 15.1 0.0 0.063 13.1 0.0 1.9 1 1 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CorA PF01544.18 ORY18704.1 - 7.5e-07 28.7 0.0 9.5e-07 28.4 0.0 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF2615 PF11027.8 ORY18704.1 - 0.041 14.0 0.0 0.073 13.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2615) VKOR PF07884.14 ORY18704.1 - 0.17 12.1 0.3 0.22 11.7 0.3 1.2 1 0 0 1 1 1 0 Vitamin K epoxide reductase family Ferric_reduct PF01794.19 ORY18707.1 - 8.4e-21 74.4 11.2 1.7e-20 73.4 11.2 1.6 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 ORY18707.1 - 1.8e-19 69.8 0.0 4.4e-19 68.6 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 ORY18707.1 - 4e-16 59.5 0.0 1.9e-15 57.3 0.0 2.1 2 1 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_6 PF00970.24 ORY18707.1 - 0.048 14.0 0.0 0.15 12.5 0.0 1.9 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain DUF983 PF06170.12 ORY18707.1 - 6.3 7.3 7.8 0.78 10.2 2.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF983) Ctr PF04145.15 ORY18709.1 - 9e-33 114.0 0.2 1.1e-32 113.7 0.2 1.1 1 0 0 1 1 1 1 Ctr copper transporter family NAC PF01849.18 ORY18710.1 - 1.4e-23 82.6 0.1 2.8e-23 81.6 0.1 1.6 1 0 0 1 1 1 1 NAC domain Adeno_PV PF03910.13 ORY18710.1 - 1.4 7.5 9.8 2.9 6.5 2.5 2.4 2 0 0 2 2 2 0 Adenovirus minor core protein PV Pyr_redox_2 PF07992.14 ORY18711.1 - 9.2e-36 123.6 0.0 1.2e-35 123.2 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORY18711.1 - 1.1e-11 45.1 0.2 1.3e-08 35.2 0.2 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ORY18711.1 - 1.2e-06 28.0 0.0 3.6e-06 26.5 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 ORY18711.1 - 0.0003 20.3 0.3 0.017 14.5 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 ORY18711.1 - 0.00033 19.6 1.1 0.0017 17.3 0.0 2.3 3 0 0 3 3 3 1 Tryptophan halogenase NAD_binding_9 PF13454.6 ORY18711.1 - 0.0018 18.3 1.0 9.2 6.2 0.0 3.7 4 0 0 4 4 4 2 FAD-NAD(P)-binding DAO PF01266.24 ORY18711.1 - 0.0045 16.6 0.3 4.8 6.7 0.0 3.6 4 0 0 4 4 4 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 ORY18711.1 - 0.013 14.8 0.0 0.018 14.3 0.0 1.3 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase RNase_PH PF01138.21 ORY18712.1 - 2.2e-19 70.3 0.0 3.7e-19 69.5 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 YdaS_antitoxin PF15943.5 ORY18712.1 - 0.12 12.3 0.2 0.19 11.6 0.2 1.3 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Pkinase PF00069.25 ORY18714.1 - 1.3e-56 191.9 0.0 4.9e-35 121.2 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORY18714.1 - 8.1e-35 120.3 0.0 5.1e-24 85.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 ORY18714.1 - 0.00055 19.3 0.0 0.0011 18.3 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 ORY18714.1 - 0.018 14.9 3.0 0.24 11.3 0.0 2.5 2 0 0 2 2 2 0 Phosphotransferase enzyme family DUF3770 PF12603.8 ORY18714.1 - 0.049 13.1 0.3 0.099 12.1 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3770) Pkinase_fungal PF17667.1 ORY18714.1 - 0.054 12.3 0.5 0.14 10.9 0.0 1.8 2 0 0 2 2 2 0 Fungal protein kinase BTB PF00651.31 ORY18715.1 - 4.6e-24 84.8 0.4 7.1e-11 42.3 0.1 2.5 2 0 0 2 2 2 2 BTB/POZ domain Ank_4 PF13637.6 ORY18715.1 - 2.2e-09 37.7 0.1 6.4e-09 36.2 0.1 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 ORY18715.1 - 2e-08 34.7 0.1 4.8e-08 33.5 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 ORY18715.1 - 2e-07 31.1 0.2 0.0027 18.1 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 ORY18715.1 - 2.5e-07 30.8 0.0 6.9e-07 29.4 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY18715.1 - 7e-06 26.0 0.7 0.018 15.5 0.1 3.2 2 0 0 2 2 2 2 Ankyrin repeat DLH PF01738.18 ORY18716.1 - 2.9e-17 63.0 0.0 3.9e-17 62.5 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 ORY18716.1 - 0.0014 18.4 0.0 0.002 17.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Fungal_trans_2 PF11951.8 ORY18717.1 - 3.2e-52 177.6 0.2 4.1e-52 177.3 0.2 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY18717.1 - 1.1e-06 28.7 10.3 1.9e-06 27.8 10.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SUR7 PF06687.12 ORY18718.1 - 6e-06 26.0 2.0 1.3e-05 25.0 2.0 1.5 1 1 0 1 1 1 1 SUR7/PalI family MARVEL PF01284.23 ORY18718.1 - 0.0035 17.4 13.9 0.0075 16.3 13.6 1.6 1 1 1 2 2 2 1 Membrane-associating domain DUF2721 PF11026.8 ORY18718.1 - 1.7 8.5 10.2 8.3 6.3 3.4 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2721) Astacin PF01400.24 ORY18719.1 - 3e-17 62.9 0.0 4.9e-16 58.9 0.0 2.1 1 1 0 1 1 1 1 Astacin (Peptidase family M12A) DUF4215 PF13948.6 ORY18719.1 - 2e-13 50.5 31.3 5.9e-07 29.8 9.8 3.7 2 1 1 3 3 3 2 Domain of unknown function (DUF4215) Peptidase_M10 PF00413.24 ORY18719.1 - 0.0027 17.6 0.2 0.061 13.2 0.0 2.2 2 0 0 2 2 2 1 Matrixin Reprolysin_5 PF13688.6 ORY18719.1 - 0.0064 16.7 0.0 0.013 15.7 0.0 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 ORY18719.1 - 0.013 15.2 0.0 0.022 14.4 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 ORY18719.1 - 0.022 15.2 0.2 0.022 15.2 0.2 1.9 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 ORY18719.1 - 0.065 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Metallopep PF12044.8 ORY18719.1 - 0.11 11.1 0.0 0.15 10.6 0.0 1.1 1 0 0 1 1 1 0 Putative peptidase family DUF4953 PF16313.5 ORY18719.1 - 0.13 11.5 0.4 0.19 10.9 0.4 1.2 1 0 0 1 1 1 0 Met-zincin Peptidase_M66 PF10462.9 ORY18719.1 - 0.18 10.7 0.1 0.27 10.1 0.1 1.2 1 0 0 1 1 1 0 Peptidase M66 adh_short PF00106.25 ORY18720.1 - 3.8e-10 39.5 0.0 1.2e-08 34.6 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY18720.1 - 1.2e-09 38.1 0.0 4.6e-08 32.9 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY18720.1 - 7.8e-05 22.7 0.0 0.00018 21.5 0.0 1.5 2 0 0 2 2 2 1 KR domain YadA_head PF05658.14 ORY18720.1 - 0.05 14.0 0.3 0.085 13.3 0.3 1.4 1 0 0 1 1 1 0 Head domain of trimeric autotransporter adhesin Kelch_4 PF13418.6 ORY18722.1 - 7.8e-10 38.6 6.1 0.0082 16.1 0.0 4.6 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_5 PF13854.6 ORY18722.1 - 7.8e-10 38.5 12.6 3.6e-08 33.2 0.2 5.8 6 0 0 6 6 6 1 Kelch motif Kelch_6 PF13964.6 ORY18722.1 - 2.5e-05 24.4 7.1 1.3 9.4 0.1 6.0 6 0 0 6 6 6 2 Kelch motif Herpes_gE PF02480.16 ORY18722.1 - 0.0079 15.0 0.0 0.013 14.3 0.0 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E Kelch_3 PF13415.6 ORY18722.1 - 0.022 15.0 9.6 6.4 7.2 0.1 5.1 4 0 0 4 4 4 0 Galactose oxidase, central domain Syndecan PF01034.20 ORY18722.1 - 0.025 14.5 0.0 0.053 13.4 0.0 1.5 1 0 0 1 1 1 0 Syndecan domain Kelch_1 PF01344.25 ORY18722.1 - 0.075 12.6 5.6 1.4 8.5 0.1 3.8 5 0 0 5 5 5 0 Kelch motif Kelch_2 PF07646.15 ORY18722.1 - 0.6 10.2 6.2 13 5.9 0.2 4.4 5 0 0 5 5 5 0 Kelch motif FAD_binding_4 PF01565.23 ORY18726.1 - 5.2e-21 74.9 1.0 9.1e-21 74.1 1.0 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 ORY18726.1 - 1.7e-10 40.8 0.1 5.9e-10 39.1 0.0 2.0 2 0 0 2 2 2 1 Berberine and berberine like IBR PF01485.21 ORY18729.1 - 3.1e-07 30.5 12.8 3.1e-07 30.5 12.8 3.4 3 1 0 3 3 3 2 IBR domain, a half RING-finger domain UBM PF14377.6 ORY18729.1 - 0.16 11.4 6.7 0.13 11.7 4.5 2.0 1 1 1 2 2 2 0 Ubiquitin binding region Fungal_trans_2 PF11951.8 ORY18732.1 - 5.1e-35 121.0 5.1 6.8e-35 120.6 5.1 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain ANAPC5 PF12862.7 ORY18732.1 - 0.013 15.6 4.6 0.18 11.9 1.8 2.7 2 1 0 3 3 3 0 Anaphase-promoting complex subunit 5 adh_short PF00106.25 ORY18733.1 - 1e-23 83.8 0.3 1.4e-23 83.4 0.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY18733.1 - 7.4e-16 58.4 0.2 9.8e-16 58.0 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 ORY18733.1 - 0.016 14.7 0.0 0.098 12.1 0.0 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family KR PF08659.10 ORY18733.1 - 0.018 15.0 0.0 0.031 14.2 0.0 1.4 1 0 0 1 1 1 0 KR domain NAD_binding_10 PF13460.6 ORY18733.1 - 0.025 14.5 0.2 0.074 12.9 0.2 1.8 1 1 0 1 1 1 0 NAD(P)H-binding AKAP7_NLS PF10469.9 ORY18734.1 - 1.9e-21 76.9 0.0 6.6e-20 71.9 0.0 2.1 1 1 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain Hpt PF01627.23 ORY18735.1 - 8.7e-12 45.1 0.2 1.7e-11 44.3 0.1 1.5 2 0 0 2 2 2 1 Hpt domain Syntaxin_2 PF14523.6 ORY18735.1 - 0.011 16.0 1.5 0.023 15.1 0.3 1.9 1 1 0 2 2 2 0 Syntaxin-like protein Tex_N PF09371.10 ORY18735.1 - 0.059 13.0 1.2 0.11 12.2 0.4 1.6 1 1 0 2 2 2 0 Tex-like protein N-terminal domain FH2 PF02181.23 ORY18735.1 - 0.088 11.9 6.8 0.041 13.0 1.6 1.9 1 1 1 2 2 2 0 Formin Homology 2 Domain DUF4201 PF13870.6 ORY18735.1 - 0.11 12.2 4.6 0.2 11.4 4.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) PRP9_N PF16958.5 ORY18735.1 - 0.69 9.9 5.8 0.25 11.4 2.0 1.9 2 0 0 2 2 2 0 Pre-mRNA-splicing factor PRP9 N-terminus Aminotran_1_2 PF00155.21 ORY18736.1 - 6.6e-89 298.6 0.0 7.7e-89 298.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II MMR_HSR1 PF01926.23 ORY18737.1 - 0.0029 17.7 0.0 3.1 7.9 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF4349 PF14257.6 ORY18737.1 - 0.22 10.9 1.7 0.43 10.0 1.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) Glyco_transf_34 PF05637.12 ORY18738.1 - 4.3e-68 229.6 0.0 5.3e-68 229.3 0.0 1.0 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family PMI_typeI PF01238.21 ORY18739.1 - 4.6e-77 259.7 0.0 7.3e-76 255.8 0.0 2.0 1 1 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.11 ORY18739.1 - 2.1e-07 30.5 0.0 0.0024 17.5 0.0 2.4 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.19 ORY18739.1 - 8.2e-06 25.8 0.0 0.0009 19.2 0.0 2.6 2 0 0 2 2 2 1 AraC-like ligand binding domain Cupin_3 PF05899.12 ORY18739.1 - 0.097 12.4 0.0 4.3 7.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF861) Nexin_C PF08628.12 ORY18741.1 - 0.073 13.7 0.3 0.42 11.2 0.1 2.1 2 0 0 2 2 2 0 Sorting nexin C terminal Syntaxin-6_N PF09177.11 ORY18741.1 - 1.6 9.3 6.2 16 6.2 0.5 3.0 3 0 0 3 3 3 0 Syntaxin 6, N-terminal SIMPL PF04402.14 ORY18741.1 - 5 7.5 5.8 53 4.2 5.4 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF541) p450 PF00067.22 ORY18743.1 - 4.8e-68 230.0 0.0 5.9e-68 229.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF4965 PF16335.5 ORY18743.1 - 0.05 13.2 0.0 0.085 12.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4965) Baculo_PEP_C PF04513.12 ORY18745.1 - 0.0034 17.4 6.6 2.5 8.2 0.1 4.1 2 2 1 3 3 3 2 Baculovirus polyhedron envelope protein, PEP, C terminus COG2 PF06148.11 ORY18745.1 - 0.025 14.7 0.1 48 4.0 0.0 3.5 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF1664 PF07889.12 ORY18745.1 - 0.087 12.9 0.6 17 5.4 0.0 3.8 4 1 0 4 4 4 0 Protein of unknown function (DUF1664) MSC PF09402.10 ORY18745.1 - 0.23 10.9 0.0 9.4 5.6 0.0 2.6 3 0 0 3 3 3 0 Man1-Src1p-C-terminal domain Senescence PF06911.12 ORY18745.1 - 0.89 9.8 3.6 33 4.7 0.2 3.1 4 0 0 4 4 4 0 Senescence-associated protein Chlorosome_CsmC PF11098.8 ORY18745.1 - 1.1 9.3 4.5 0.85 9.6 0.8 2.5 2 1 0 2 2 2 0 Chlorosome envelope protein C HbrB PF08539.11 ORY18747.1 - 2e-49 167.8 1.2 4.1e-49 166.8 0.0 2.2 2 0 0 2 2 2 1 HbrB-like Gon7 PF08738.10 ORY18748.1 - 2.2e-06 27.7 2.6 8.4e-06 25.8 0.2 2.0 1 1 1 2 2 2 1 Gon7 family Spore_Cse60 PF10957.8 ORY18748.1 - 0.03 14.4 0.1 0.039 14.0 0.1 1.2 1 0 0 1 1 1 0 Sporulation protein Cse60 Vps39_2 PF10367.9 ORY18749.1 - 6.5e-34 116.7 0.1 8.8e-33 113.0 0.0 2.6 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.9 ORY18749.1 - 5.7e-32 110.2 0.0 5.3e-31 107.1 0.0 2.7 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 CNH PF00780.22 ORY18749.1 - 6.2e-21 75.2 0.0 3e-20 73.0 0.0 2.0 1 1 0 1 1 1 1 CNH domain Clathrin PF00637.20 ORY18749.1 - 1e-07 31.9 2.0 1e-07 31.9 2.0 2.5 3 0 0 3 3 3 1 Region in Clathrin and VPS TPR_16 PF13432.6 ORY18749.1 - 0.00098 19.7 0.6 3.2 8.5 0.1 4.3 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 ORY18749.1 - 0.024 14.4 6.1 2.2 8.2 1.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.6 ORY18749.1 - 0.042 14.0 0.0 10 6.4 0.0 4.0 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 ORY18749.1 - 0.088 13.1 0.8 2.2 8.7 0.8 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 ORY18749.1 - 0.21 11.8 7.4 21 5.5 0.7 4.5 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 ORY18749.1 - 0.99 9.7 5.9 90 3.5 0.0 4.5 4 1 1 5 5 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY18749.1 - 2.2 8.6 4.4 3.4 8.0 0.1 3.3 3 2 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF4050 PF13259.6 ORY18750.1 - 5.8e-52 176.7 0.4 8.4e-52 176.2 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4050) Mus7 PF09462.10 ORY18751.1 - 1.1e-130 437.5 0.1 2e-130 436.6 0.1 1.5 1 0 0 1 1 1 1 Mus7/MMS22 family PPTA PF01239.22 ORY18752.1 - 1.4e-43 145.4 21.4 1e-08 34.6 2.2 6.1 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat DUF3950 PF13132.6 ORY18752.1 - 0.082 12.7 2.1 3.7 7.4 0.4 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3950) RRT14 PF17075.5 ORY18752.1 - 0.083 13.0 0.1 0.5 10.5 0.0 2.0 2 0 0 2 2 2 0 Regular of rDNA transcription protein 14 ANAPC4_WD40 PF12894.7 ORY18753.1 - 8.6e-07 29.2 0.0 0.23 11.8 0.0 4.2 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 ORY18753.1 - 0.23 12.4 8.6 0.33 11.9 0.0 5.0 7 0 0 7 7 7 0 WD domain, G-beta repeat Ribosomal_S6e PF01092.19 ORY18754.1 - 2.4e-57 192.3 0.0 4.5e-57 191.4 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S6e Atg14 PF10186.9 ORY18754.1 - 1.2 8.1 5.8 1.6 7.8 5.8 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Pribosyltran_N PF13793.6 ORY18755.1 - 5.4e-45 152.1 0.1 1.9e-44 150.3 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 ORY18755.1 - 1.9e-44 151.9 1.3 1.1e-37 129.8 1.2 2.4 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 ORY18755.1 - 7.8e-17 61.2 2.2 1.7e-15 56.9 1.4 2.3 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 ORY18755.1 - 0.00081 18.9 0.2 0.0014 18.1 0.2 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Uds1 PF15456.6 ORY18756.1 - 2.3e-29 102.2 8.9 2.3e-29 102.2 8.9 1.7 2 0 0 2 2 2 1 Up-regulated During Septation Stathmin PF00836.19 ORY18756.1 - 0.022 14.7 0.6 0.022 14.7 0.6 2.2 3 0 0 3 3 3 0 Stathmin family APG6_N PF17675.1 ORY18756.1 - 0.25 11.9 4.4 0.56 10.7 4.4 1.6 1 0 0 1 1 1 0 Apg6 coiled-coil region Fanconi_A PF03511.14 ORY18758.1 - 0.11 12.4 0.1 1.7 8.6 0.0 2.3 2 0 0 2 2 2 0 Fanconi anaemia group A protein tRNA-synt_2d PF01409.20 ORY18759.1 - 2.4e-48 164.8 0.1 1e-26 93.9 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 ORY18759.1 - 1.6e-26 92.5 0.0 3.6e-26 91.4 0.0 1.6 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain Mito_carr PF00153.27 ORY18760.1 - 0.0015 18.4 0.0 0.0021 17.9 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial carrier protein Mito_carr PF00153.27 ORY18761.1 - 1.8e-45 152.8 0.2 2.7e-17 62.4 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3764 PF12594.8 ORY18761.1 - 0.074 13.1 0.0 12 6.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3764) Calcipressin PF04847.12 ORY18762.1 - 2.2e-42 144.9 0.3 2.7e-42 144.6 0.3 1.1 1 0 0 1 1 1 1 Calcipressin RRM_1 PF00076.22 ORY18762.1 - 0.008 16.0 0.0 0.014 15.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_pol_A_bac PF01000.26 ORY18763.1 - 1.7e-30 105.7 0.0 2.7e-30 105.0 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 ORY18763.1 - 3.8e-16 58.3 0.0 5.1e-16 57.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain HK PF02110.15 ORY18763.1 - 0.053 12.9 0.0 0.085 12.2 0.0 1.2 1 0 0 1 1 1 0 Hydroxyethylthiazole kinase family GrpE PF01025.19 ORY18764.1 - 3.9e-48 163.2 1.2 5e-48 162.9 1.2 1.1 1 0 0 1 1 1 1 GrpE PKcGMP_CC PF16808.5 ORY18764.1 - 0.015 15.1 0.3 0.04 13.8 0.3 1.7 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase HIP1_clath_bdg PF16515.5 ORY18764.1 - 0.033 14.8 3.7 2.8 8.6 0.8 2.3 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Tropomyosin_1 PF12718.7 ORY18764.1 - 0.056 13.6 2.9 0.085 13.0 2.9 1.2 1 0 0 1 1 1 0 Tropomyosin like PrpF PF04303.13 ORY18765.1 - 5e-91 305.4 0.5 1.8e-90 303.6 0.5 1.7 1 1 0 1 1 1 1 PrpF protein PHY PF00360.20 ORY18765.1 - 0.12 11.6 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Phytochrome region MFS_1 PF07690.16 ORY18766.1 - 1.2e-38 133.0 43.0 1.8e-38 132.4 43.0 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 ORY18766.1 - 4.6e-19 68.3 12.7 5.7e-19 68.0 12.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) AzlD PF05437.12 ORY18766.1 - 0.12 12.6 0.1 0.12 12.6 0.1 3.6 4 1 0 4 4 4 0 Branched-chain amino acid transport protein (AzlD) PAC4 PF16093.5 ORY18769.1 - 0.068 13.4 0.0 0.095 12.9 0.0 1.3 1 0 0 1 1 1 0 Proteasome assembly chaperone 4 Ribosomal_L30 PF00327.20 ORY18770.1 - 3.5e-15 55.6 0.3 4.8e-15 55.2 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e SRA1 PF07304.11 ORY18771.1 - 5e-10 39.4 3.6 5e-10 39.4 3.6 3.5 2 1 1 3 3 3 1 Steroid receptor RNA activator (SRA1) Sec16_C PF12931.7 ORY18771.1 - 0.002 17.8 0.9 0.017 14.8 0.9 2.2 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 Prp18 PF02840.15 ORY18771.1 - 0.0045 17.0 0.8 0.014 15.5 0.1 2.1 2 1 0 2 2 2 1 Prp18 domain WD40 PF00400.32 ORY18771.1 - 0.0055 17.5 8.1 0.45 11.5 0.2 5.8 7 0 0 7 7 7 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY18771.1 - 0.057 13.7 0.0 1.4 9.3 0.0 2.8 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain TPR_19 PF14559.6 ORY18771.1 - 0.077 13.5 0.7 11 6.7 0.3 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 ORY18771.1 - 0.18 12.7 1.3 14 6.8 0.4 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat RRM_1 PF00076.22 ORY18772.1 - 3.5e-18 65.2 0.0 4.9e-18 64.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 ORY18772.1 - 0.00075 19.6 0.1 0.0013 18.8 0.0 1.5 1 1 0 1 1 1 1 RNA recognition motif RRM_5 PF13893.6 ORY18772.1 - 0.046 13.3 0.0 0.093 12.3 0.0 1.6 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SET_assoc PF11767.8 ORY18772.1 - 0.15 11.7 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated Limkain-b1 PF11608.8 ORY18772.1 - 0.18 11.9 0.0 0.4 10.8 0.0 1.5 1 0 0 1 1 1 0 Limkain b1 COX6B PF02297.17 ORY18774.1 - 8.9e-19 67.5 2.9 1e-18 67.3 2.9 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb CX9C PF16860.5 ORY18774.1 - 0.013 15.5 1.7 0.021 14.8 1.7 1.3 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, APOBEC_C PF05240.14 ORY18774.1 - 0.025 14.5 0.1 0.034 14.1 0.1 1.3 1 0 0 1 1 1 0 APOBEC-like C-terminal domain ketoacyl-synt PF00109.26 ORY18774.1 - 0.12 11.9 0.0 0.13 11.8 0.0 1.1 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain RasGEF PF00617.19 ORY18775.1 - 3.4e-42 144.6 0.0 6.5e-42 143.7 0.0 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 ORY18775.1 - 4.3e-11 43.0 0.0 1.1e-10 41.6 0.0 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif Ras PF00071.22 ORY18775.1 - 4.9e-06 26.2 0.0 4e-05 23.3 0.0 2.3 1 1 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 ORY18775.1 - 0.18 11.9 0.0 0.69 10.0 0.0 2.1 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF4188 PF13826.6 ORY18776.1 - 3.4e-22 79.0 0.9 4.8e-22 78.5 0.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4188) Ctr PF04145.15 ORY18778.1 - 0.1 13.2 0.4 7.4 7.2 0.0 2.1 2 0 0 2 2 2 0 Ctr copper transporter family IMS PF00817.20 ORY18781.1 - 6.6e-40 136.5 0.0 1.1e-39 135.8 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 ORY18781.1 - 4.6e-17 62.8 0.1 3.2e-16 60.1 0.1 2.2 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain zf_UBZ PF18439.1 ORY18781.1 - 0.00012 21.6 0.3 0.00025 20.5 0.3 1.5 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger IMS_HHH PF11798.8 ORY18781.1 - 0.0014 18.8 0.0 0.004 17.4 0.0 1.8 1 0 0 1 1 1 1 IMS family HHH motif Pyridoxal_deC PF00282.19 ORY18782.1 - 1.3e-16 60.3 0.0 2e-16 59.7 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 ORY18782.1 - 9.1e-06 24.9 0.0 1.5e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 ORY18782.1 - 0.02 14.2 0.0 0.031 13.6 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 ORY18782.1 - 0.13 10.8 0.0 0.19 10.2 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Ribosomal_L7Ae PF01248.26 ORY18783.1 - 1.5e-06 27.9 0.0 1.9e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Ribosomal_L16 PF00252.18 ORY18784.1 - 1.9e-32 112.1 0.2 4.2e-32 110.9 0.1 1.6 2 0 0 2 2 2 1 Ribosomal protein L16p/L10e RFC1 PF08519.12 ORY18785.1 - 6.6e-59 198.6 0.7 6.1e-58 195.4 0.2 2.3 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain BRCT PF00533.26 ORY18785.1 - 2.9e-14 53.2 0.0 7.2e-14 51.9 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.29 ORY18785.1 - 4.5e-10 40.1 0.1 1.8e-09 38.1 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 ORY18785.1 - 4.1e-05 23.6 0.0 0.00016 21.6 0.0 1.9 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_33 PF13671.6 ORY18785.1 - 0.00078 19.6 0.1 0.0028 17.8 0.1 1.9 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 ORY18785.1 - 0.0034 17.8 2.6 2.1 8.7 0.1 3.2 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.12 ORY18785.1 - 0.0049 16.6 0.0 0.0097 15.7 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 ORY18785.1 - 0.0054 17.1 3.6 0.018 15.4 0.1 3.0 2 1 1 3 3 3 1 AAA ATPase domain TMV_coat PF00721.21 ORY18785.1 - 0.012 15.4 1.7 0.03 14.2 1.7 1.6 1 0 0 1 1 1 0 Virus coat protein (TMV like) AAA_22 PF13401.6 ORY18785.1 - 0.015 15.6 0.0 0.063 13.6 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 ORY18785.1 - 0.028 14.4 0.0 0.068 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 ORY18785.1 - 0.082 13.4 1.3 0.15 12.6 0.0 2.1 2 0 0 2 2 1 0 AAA domain AAA_14 PF13173.6 ORY18785.1 - 0.11 12.6 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 ORY18785.1 - 0.19 12.0 6.2 0.67 10.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF1414 PF07208.11 ORY18786.1 - 0.031 14.3 0.5 9.5 6.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1414) DUF4658 PF15555.6 ORY18786.1 - 0.13 12.3 1.5 0.35 11.0 1.5 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4658) Dzip-like_N PF13815.6 ORY18786.1 - 0.55 10.2 2.3 0.64 10.0 0.5 2.0 2 0 0 2 2 2 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal HET PF06985.11 ORY18787.1 - 3.5e-36 124.8 0.4 4.6e-36 124.4 0.4 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF815 PF05673.13 ORY18787.1 - 0.096 11.8 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ICL PF00463.21 ORY18787.1 - 0.11 11.0 0.0 0.13 10.7 0.0 1.1 1 0 0 1 1 1 0 Isocitrate lyase family Ank_4 PF13637.6 ORY18788.1 - 6.4e-32 109.5 1.0 2e-12 47.4 0.0 3.6 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 ORY18788.1 - 2e-28 98.8 0.5 1.8e-14 54.1 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ORY18788.1 - 3.2e-20 71.9 0.1 4.9e-08 33.1 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 ORY18788.1 - 2.5e-16 59.3 2.5 0.00013 22.3 0.1 4.5 4 1 1 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 ORY18788.1 - 6.8e-16 56.8 0.2 0.0013 19.0 0.0 4.4 5 0 0 5 5 5 4 Ankyrin repeat TPR_1 PF00515.28 ORY18789.1 - 4e-57 187.8 22.4 1.1e-08 34.6 0.0 10.7 11 1 0 11 11 10 9 Tetratricopeptide repeat TPR_2 PF07719.17 ORY18789.1 - 1.9e-50 164.9 14.9 4e-06 26.5 0.0 10.5 11 0 0 11 11 10 9 Tetratricopeptide repeat TPR_8 PF13181.6 ORY18789.1 - 1.3e-42 140.4 14.7 1.3e-05 25.0 0.0 10.7 10 1 0 10 10 10 9 Tetratricopeptide repeat TPR_17 PF13431.6 ORY18789.1 - 4.9e-31 104.8 13.7 1.9e-05 24.7 0.1 10.4 11 0 0 11 11 11 6 Tetratricopeptide repeat TPR_11 PF13414.6 ORY18789.1 - 4.1e-27 93.6 23.1 9.8e-07 28.4 1.0 9.6 5 2 4 9 9 9 6 TPR repeat TPR_19 PF14559.6 ORY18789.1 - 7.5e-25 87.2 8.7 0.00027 21.4 0.1 7.1 4 2 3 7 7 7 6 Tetratricopeptide repeat TPR_16 PF13432.6 ORY18789.1 - 7.5e-25 87.3 12.6 2.8e-07 31.1 0.1 7.3 5 2 2 8 8 7 4 Tetratricopeptide repeat TPR_12 PF13424.6 ORY18789.1 - 1.7e-24 85.9 13.5 2.5e-05 24.5 0.6 7.6 4 2 2 6 6 6 5 Tetratricopeptide repeat TPR_7 PF13176.6 ORY18789.1 - 3.6e-23 79.9 10.6 0.0094 15.9 0.1 9.6 9 1 0 9 9 9 5 Tetratricopeptide repeat TPR_14 PF13428.6 ORY18789.1 - 5.8e-23 79.6 14.9 1.7e-05 25.2 0.0 8.9 5 3 4 9 9 8 6 Tetratricopeptide repeat TPR_6 PF13174.6 ORY18789.1 - 4.8e-21 73.9 18.6 0.0062 17.1 0.0 9.6 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_9 PF13371.6 ORY18789.1 - 2.5e-15 56.4 8.4 0.00058 20.0 0.1 6.8 1 1 6 8 8 8 6 Tetratricopeptide repeat TPR_15 PF13429.6 ORY18789.1 - 3.6e-11 42.8 7.1 0.0046 16.2 0.7 5.3 1 1 1 4 4 4 4 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY18789.1 - 1.1e-08 35.2 11.8 6.1e-08 32.8 2.5 3.7 4 1 0 4 4 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_21 PF09976.9 ORY18789.1 - 8.9e-08 32.1 3.5 0.14 11.9 0.0 4.6 4 2 1 5 5 5 3 Tetratricopeptide repeat-like domain BTAD PF03704.17 ORY18789.1 - 7.7e-06 26.4 4.0 0.55 10.7 0.0 3.7 3 1 0 3 3 3 3 Bacterial transcriptional activator domain Syntaxin-6_N PF09177.11 ORY18789.1 - 0.00059 20.3 0.3 2 9.0 0.0 2.7 2 0 0 2 2 2 2 Syntaxin 6, N-terminal Fis1_TPR_C PF14853.6 ORY18789.1 - 0.0015 18.5 0.1 19 5.4 0.0 4.6 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_20 PF14561.6 ORY18789.1 - 0.0095 16.3 1.0 0.64 10.4 0.0 3.9 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 ORY18789.1 - 0.016 15.1 16.0 11 6.1 0.0 7.6 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_MalT PF17874.1 ORY18789.1 - 0.019 14.3 5.0 0.56 9.5 0.1 3.3 2 1 1 3 3 3 0 MalT-like TPR region DUF2225 PF09986.9 ORY18789.1 - 0.019 14.7 3.4 0.39 10.4 0.1 3.1 2 2 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) Clathrin PF00637.20 ORY18789.1 - 0.032 14.1 0.8 2.5 8.0 0.0 3.6 3 1 1 4 4 4 0 Region in Clathrin and VPS ChAPs PF09295.10 ORY18789.1 - 0.049 12.6 1.1 5.3 5.9 0.2 3.0 2 1 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) SNAP PF14938.6 ORY18789.1 - 0.11 11.9 15.8 14 5.0 0.1 5.2 1 1 4 5 5 5 0 Soluble NSF attachment protein, SNAP MIT PF04212.18 ORY18789.1 - 0.77 9.9 19.7 24 5.1 2.7 6.6 6 1 0 6 6 6 0 MIT (microtubule interacting and transport) domain NuiA PF07924.11 ORY18790.1 - 9.3e-07 29.3 0.3 0.0027 18.1 0.1 2.4 1 1 0 1 1 1 1 Nuclease A inhibitor-like protein Prefoldin_3 PF13758.6 ORY18790.1 - 0.015 15.3 0.0 0.027 14.5 0.0 1.4 1 0 0 1 1 1 0 Prefoldin subunit SKN1 PF03935.15 ORY18792.1 - 6.7e-233 773.6 0.2 7.8e-233 773.4 0.2 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Zn_ribbon_17 PF17120.5 ORY18794.1 - 1.1e-11 44.2 11.4 6.6e-09 35.3 1.6 2.4 2 0 0 2 2 2 2 Zinc-ribbon, C4HC2 type WD40 PF00400.32 ORY18794.1 - 1.1e-07 32.4 15.7 0.00097 19.9 0.3 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat zf-RING_2 PF13639.6 ORY18794.1 - 0.0074 16.6 3.8 0.016 15.5 3.8 1.6 1 0 0 1 1 1 1 Ring finger domain C1_2 PF03107.16 ORY18794.1 - 0.01 16.2 1.5 0.024 15.0 1.5 1.6 1 0 0 1 1 1 0 C1 domain zf-RING_11 PF17123.5 ORY18794.1 - 0.57 10.0 5.9 1.3 8.8 5.9 1.7 1 0 0 1 1 1 0 RING-like zinc finger PHD PF00628.29 ORY18794.1 - 1.2 9.1 5.3 0.37 10.7 2.3 1.7 2 0 0 2 2 2 0 PHD-finger zf-RING_UBOX PF13445.6 ORY18794.1 - 2.7 8.1 5.0 6.4 6.9 5.0 1.6 1 0 0 1 1 1 0 RING-type zinc-finger UQ_con PF00179.26 ORY18795.1 - 4e-48 162.6 0.0 4.5e-48 162.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 ORY18795.1 - 0.00045 19.9 0.0 0.00057 19.6 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 ORY18795.1 - 0.027 14.3 0.1 0.055 13.3 0.1 1.6 1 1 0 1 1 1 0 UEV domain RWD PF05773.22 ORY18795.1 - 0.079 13.3 0.2 0.13 12.6 0.2 1.5 1 1 0 1 1 1 0 RWD domain Pkinase PF00069.25 ORY18796.1 - 6.7e-25 87.9 0.0 1.1e-24 87.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY18796.1 - 1.1e-18 67.5 0.0 1.6e-18 66.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORY18796.1 - 0.084 11.6 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase DUF1287 PF06940.11 ORY18796.1 - 0.13 11.9 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1287) HSP70 PF00012.20 ORY18798.1 - 4.8e-09 35.0 0.0 2.2e-08 32.8 0.0 1.8 2 0 0 2 2 2 1 Hsp70 protein Leu_zip PF15294.6 ORY18799.1 - 0.0037 16.8 1.5 0.0056 16.2 1.5 1.2 1 0 0 1 1 1 1 Leucine zipper TolA_bind_tri PF16331.5 ORY18799.1 - 0.011 15.7 0.5 0.03 14.4 0.5 1.7 1 0 0 1 1 1 0 TolA binding protein trimerisation Terminase_4 PF05119.12 ORY18799.1 - 0.012 16.0 0.8 0.032 14.6 0.8 1.7 1 0 0 1 1 1 0 Phage terminase, small subunit DUF3450 PF11932.8 ORY18799.1 - 0.022 14.1 2.4 0.048 13.0 2.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) FTA4 PF13093.6 ORY18799.1 - 0.047 13.6 1.4 0.23 11.3 0.9 2.0 2 0 0 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DHR10 PF18595.1 ORY18799.1 - 0.069 13.2 1.9 0.12 12.4 1.1 1.8 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain Tho2 PF11262.8 ORY18799.1 - 0.097 11.9 0.4 0.24 10.6 0.1 1.5 1 1 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 CHD5 PF04420.14 ORY18799.1 - 0.099 12.5 1.8 0.2 11.5 1.8 1.4 1 0 0 1 1 1 0 CHD5-like protein TMCO5 PF14992.6 ORY18799.1 - 0.14 11.7 1.7 0.24 10.9 1.7 1.3 1 0 0 1 1 1 0 TMCO5 family HALZ PF02183.18 ORY18799.1 - 0.15 12.3 0.7 0.38 11.0 0.2 1.9 2 0 0 2 2 2 0 Homeobox associated leucine zipper Lyase_1 PF00206.20 ORY18800.1 - 1.4e-89 300.5 0.0 3.3e-89 299.4 0.0 1.6 2 0 0 2 2 2 1 Lyase ASL_C2 PF14698.6 ORY18800.1 - 4.4e-22 78.6 0.0 1.3e-21 77.1 0.0 1.9 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal DUF5316 PF17247.2 ORY18801.1 - 0.021 14.8 1.5 0.021 14.8 1.5 1.7 1 1 0 1 1 1 0 Family of unknown function (DUF5316) Clostridium_P47 PF06597.11 ORY18801.1 - 0.46 9.1 6.4 0.52 9.0 6.4 1.0 1 0 0 1 1 1 0 Clostridium P-47 protein TRP PF06011.12 ORY18802.1 - 2.9e-126 421.7 15.3 3.8e-126 421.2 15.3 1.2 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 ORY18802.1 - 1.1e-39 136.0 0.0 1.7e-39 135.4 0.0 1.3 1 0 0 1 1 1 1 ML-like domain SP_C-Propep PF08999.10 ORY18802.1 - 0.1 12.4 1.1 0.37 10.6 1.1 1.9 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide 4HBT PF03061.22 ORY18804.1 - 0.0035 17.7 0.0 0.0076 16.6 0.0 1.6 1 0 0 1 1 1 1 Thioesterase superfamily GFA PF04828.14 ORY18805.1 - 0.0001 22.6 0.3 0.0001 22.6 0.3 1.8 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme zf-NADH-PPase PF09297.11 ORY18805.1 - 0.012 15.2 0.6 0.012 15.2 0.6 2.3 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain zf-C2H2 PF00096.26 ORY18809.1 - 6.6e-12 45.2 11.0 6.9e-06 26.2 0.7 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY18809.1 - 1.8e-09 37.6 9.1 0.0002 21.9 0.7 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORY18809.1 - 2.1e-07 31.1 12.9 1.7e-05 25.0 2.5 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 ORY18809.1 - 9.4e-05 22.6 3.4 0.0037 17.5 0.1 2.6 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 ORY18809.1 - 0.00015 21.4 7.7 0.019 14.7 0.2 2.5 2 0 0 2 2 2 2 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 ORY18809.1 - 0.0083 16.1 7.6 0.51 10.4 0.4 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 ORY18809.1 - 0.049 13.4 2.2 2 8.2 0.2 2.6 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-met PF12874.7 ORY18809.1 - 0.44 11.0 0.1 0.44 11.0 0.1 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type eIF-3_zeta PF05091.12 ORY18809.1 - 0.64 8.9 6.7 0.86 8.5 6.7 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) AIF_C PF14721.6 ORY18809.1 - 1.2 9.5 4.0 2.3 8.6 4.0 1.4 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Presenilin PF01080.17 ORY18809.1 - 1.7 7.4 6.8 2.1 7.0 6.8 1.2 1 0 0 1 1 1 0 Presenilin zf-C2HE PF16278.5 ORY18809.1 - 1.7 9.1 15.6 0.83 10.1 1.4 2.6 2 1 1 3 3 2 0 C2HE / C2H2 / C2HC zinc-binding finger DUF4407 PF14362.6 ORY18809.1 - 4.5 6.5 4.9 6.1 6.1 4.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) zf-AN1 PF01428.16 ORY18809.1 - 6.4 7.0 8.5 17 5.7 1.8 2.5 1 1 1 2 2 2 0 AN1-like Zinc finger API5 PF05918.11 ORY18809.1 - 7.7 5.2 10.1 11 4.6 10.1 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Pkinase PF00069.25 ORY18810.1 - 3.7e-65 219.9 0.1 3.2e-64 216.8 0.1 2.1 1 1 0 1 1 1 1 Protein kinase domain Fungal_KA1 PF16797.5 ORY18810.1 - 2.7e-35 120.6 0.1 5.2e-35 119.7 0.1 1.5 1 0 0 1 1 1 1 Fungal kinase associated-1 domain Pkinase_Tyr PF07714.17 ORY18810.1 - 2.7e-28 99.0 0.0 6e-28 97.8 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 ORY18810.1 - 0.0023 17.3 0.2 0.0049 16.2 0.2 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 ORY18810.1 - 0.0044 16.0 0.4 0.012 14.6 0.4 1.7 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 ORY18810.1 - 0.014 15.3 1.2 0.031 14.2 0.1 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 ORY18810.1 - 0.085 12.4 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Ribosomal_L24e PF01246.20 ORY18811.1 - 1.2e-28 99.1 0.3 1.2e-28 99.1 0.3 1.7 2 0 0 2 2 2 1 Ribosomal protein L24e adh_short PF00106.25 ORY18813.1 - 1.3e-41 142.3 1.2 1.6e-41 141.9 1.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY18813.1 - 1.7e-38 132.5 0.1 2.4e-38 132.0 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY18813.1 - 1e-08 35.3 1.1 1e-07 32.1 1.1 2.2 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 ORY18813.1 - 0.00036 19.8 0.4 0.00062 19.0 0.4 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein ADH_zinc_N PF00107.26 ORY18813.1 - 0.0013 18.7 0.2 0.0024 17.8 0.2 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Shikimate_DH PF01488.20 ORY18813.1 - 0.0068 16.5 0.1 0.013 15.6 0.1 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Glu_dehyd_C PF16912.5 ORY18813.1 - 0.026 14.0 0.0 0.042 13.3 0.0 1.3 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus F420_oxidored PF03807.17 ORY18813.1 - 0.062 13.9 0.7 0.15 12.7 0.7 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Chitin_bind_1 PF00187.19 ORY18814.1 - 8.8e-18 64.5 58.3 3.6e-09 36.9 12.6 3.9 3 1 0 3 3 3 3 Chitin recognition protein JmjC PF02373.22 ORY18817.1 - 0.044 14.2 0.0 0.074 13.5 0.0 1.5 1 0 0 1 1 1 0 JmjC domain, hydroxylase Ribosomal_L28 PF00830.19 ORY18818.1 - 1.5e-16 60.3 0.3 2.8e-16 59.4 0.3 1.5 1 0 0 1 1 1 1 Ribosomal L28 family PTH2 PF01981.16 ORY18819.1 - 4.3e-46 156.0 0.0 5.4e-46 155.7 0.0 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 PhzC-PhzF PF02567.16 ORY18819.1 - 0.11 11.9 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Phenazine biosynthesis-like protein SART-1 PF03343.13 ORY18820.1 - 4.1e-172 574.0 69.1 4.8e-172 573.8 69.1 1.0 1 0 0 1 1 1 1 SART-1 family CH_2 PF06294.11 ORY18820.1 - 0.053 13.6 0.9 0.14 12.3 0.9 1.6 1 0 0 1 1 1 0 CH-like domain in sperm protein Glyco_hydro_59 PF02057.15 ORY18821.1 - 3e-16 59.5 3.9 5.7e-16 58.6 3.9 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 59 Glyco_hydr_30_2 PF14587.6 ORY18821.1 - 2.2e-15 57.1 4.8 1e-14 55.0 0.1 2.1 1 1 1 2 2 2 2 O-Glycosyl hydrolase family 30 Glyco_hydro_30C PF17189.4 ORY18821.1 - 1.4e-11 44.5 9.4 1.9e-10 40.8 9.4 2.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain Glyco_hydro_30 PF02055.16 ORY18821.1 - 1.4e-08 34.1 0.5 2.3e-08 33.4 0.2 1.4 2 0 0 2 2 2 1 Glycosyl hydrolase family 30 TIM-barrel domain Peptidase_M14 PF00246.24 ORY18822.1 - 3.2e-65 220.8 0.1 4e-65 220.5 0.1 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.16 ORY18822.1 - 0.014 15.7 0.0 0.028 14.8 0.0 1.5 1 0 0 1 1 1 0 Carboxypeptidase activation peptide Ferric_reduct PF01794.19 ORY18826.1 - 2.9e-06 27.4 10.6 0.00063 19.9 3.0 3.2 3 0 0 3 3 3 2 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 ORY18826.1 - 0.00076 19.5 0.0 0.0015 18.6 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain ATPase_gene1 PF09527.10 ORY18826.1 - 0.97 9.7 6.3 2.2 8.5 6.3 1.6 1 0 0 1 1 1 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter Cutinase PF01083.22 ORY18828.1 - 5.2e-51 173.1 8.5 6e-51 172.9 8.5 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 ORY18828.1 - 8.8e-06 25.4 0.1 1.2e-05 25.0 0.1 1.2 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_6 PF12697.7 ORY18828.1 - 0.048 14.2 0.1 0.059 14.0 0.1 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family VirJ PF06057.11 ORY18828.1 - 0.13 12.1 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) HET PF06985.11 ORY18829.1 - 1.6e-24 86.9 0.1 3.4e-24 85.9 0.1 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) p450 PF00067.22 ORY18831.1 - 1.1e-48 166.2 0.0 2.6e-44 151.8 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 Sulfate_transp PF00916.20 ORY18832.1 - 5.5e-87 292.0 22.0 8.4e-87 291.4 22.0 1.3 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 ORY18832.1 - 3e-13 49.4 0.0 7.2e-13 48.2 0.0 1.6 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 ORY18832.1 - 0.0011 19.2 0.0 0.0025 18.1 0.0 1.6 1 0 0 1 1 1 1 STAS domain L51_S25_CI-B8 PF05047.16 ORY18834.1 - 2.6e-13 49.7 0.0 4.5e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain 40S_SA_C PF16122.5 ORY18835.1 - 4.5 8.7 6.1 3.3 9.1 1.6 2.5 2 1 1 3 3 3 0 40S ribosomal protein SA C-terminus DUF4448 PF14610.6 ORY18836.1 - 2.8e-39 134.9 0.3 4.1e-39 134.3 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) LapA_dom PF06305.11 ORY18836.1 - 0.18 11.7 0.5 0.45 10.4 0.5 1.6 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain FixS PF03597.15 ORY18836.1 - 0.33 10.7 1.0 0.73 9.6 1.0 1.6 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type GET2 PF08690.10 ORY18837.1 - 4.7e-27 95.5 2.5 1.5e-25 90.5 2.5 2.2 1 1 0 1 1 1 1 GET complex subunit GET2 TRAM_LAG1_CLN8 PF03798.16 ORY18837.1 - 0.026 14.3 0.9 0.037 13.8 0.9 1.2 1 0 0 1 1 1 0 TLC domain DLL_N PF12413.8 ORY18838.1 - 0.1 13.8 0.3 0.15 13.4 0.3 1.2 1 0 0 1 1 1 0 Homeobox protein distal-less-like N terminal LAM_C PF12544.8 ORY18839.1 - 7.4e-05 22.9 0.0 0.00014 22.0 0.0 1.4 1 0 0 1 1 1 1 Lysine-2,3-aminomutase Radical_SAM PF04055.21 ORY18839.1 - 0.00013 22.4 0.2 0.0013 19.2 0.1 2.4 2 1 0 2 2 2 1 Radical SAM superfamily Fer4_14 PF13394.6 ORY18839.1 - 0.073 13.2 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 4Fe-4S single cluster domain adh_short PF00106.25 ORY18840.1 - 2.2e-36 125.2 0.0 3.1e-36 124.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY18840.1 - 5.7e-22 78.4 0.0 7.1e-22 78.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 ORY18840.1 - 0.021 14.2 0.0 0.077 12.4 0.0 1.7 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) MNHE PF01899.16 ORY18840.1 - 0.076 12.8 0.2 0.21 11.3 0.1 1.7 1 1 1 2 2 2 0 Na+/H+ ion antiporter subunit Methyltransf_23 PF13489.6 ORY18841.1 - 5.9e-11 42.5 0.0 9.9e-11 41.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY18841.1 - 4.7e-06 27.3 0.0 9.4e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY18841.1 - 1.4e-05 25.0 0.0 3.4e-05 23.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY18841.1 - 2.8e-05 24.7 0.0 0.00031 21.3 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY18841.1 - 0.013 16.2 0.0 0.18 12.6 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase domain SKG6 PF08693.10 ORY18842.1 - 0.0032 16.9 2.1 0.0055 16.1 2.1 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Orthoreo_P10 PF07204.11 ORY18842.1 - 0.0041 17.0 0.0 0.0095 15.9 0.0 1.7 1 0 0 1 1 1 1 Orthoreovirus membrane fusion protein p10 Mid2 PF04478.12 ORY18842.1 - 0.073 12.9 0.2 0.13 12.1 0.2 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor adh_short PF00106.25 ORY18843.1 - 4.2e-24 85.1 1.7 1.2e-14 54.2 0.4 3.1 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 ORY18843.1 - 2.9e-19 69.6 0.4 4.3e-11 42.8 0.0 2.9 3 0 0 3 3 3 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY18843.1 - 0.00074 19.5 0.1 0.0019 18.2 0.0 1.6 2 0 0 2 2 2 1 KR domain ADH_zinc_N PF00107.26 ORY18843.1 - 0.036 14.1 0.0 4.3 7.3 0.0 2.3 1 1 1 2 2 2 0 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ORY18843.1 - 0.13 13.3 0.1 1 10.4 0.1 2.1 1 1 0 1 1 1 0 Zinc-binding dehydrogenase NAD_binding_6 PF08030.12 ORY18844.1 - 4.8e-19 69.0 0.0 2.9e-18 66.5 0.0 2.1 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 ORY18844.1 - 1.5e-16 60.7 13.7 3.9e-16 59.3 13.7 1.8 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 ORY18844.1 - 2.4e-12 46.9 0.0 1.1e-11 44.7 0.0 2.2 2 1 0 2 2 2 1 FAD-binding domain NAD_binding_1 PF00175.21 ORY18844.1 - 0.00016 22.2 0.0 0.1 13.2 0.0 2.4 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain Fungal_trans_2 PF11951.8 ORY18845.1 - 0.043 12.6 0.0 0.062 12.1 0.0 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain WH1 PF00568.23 ORY18846.1 - 5e-29 100.5 0.1 7.5e-29 99.9 0.1 1.3 1 0 0 1 1 1 1 WH1 domain Mit_KHE1 PF10173.9 ORY18847.1 - 0.014 15.5 0.0 0.033 14.3 0.0 1.6 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related Cupin_2 PF07883.11 ORY18848.1 - 0.14 11.9 0.1 0.24 11.2 0.1 1.6 1 1 0 1 1 1 0 Cupin domain Dynamin_N PF00350.23 ORY18850.1 - 3.4e-38 131.4 0.2 3.4e-38 131.4 0.2 2.0 2 0 0 2 2 2 1 Dynamin family Dynamin_M PF01031.20 ORY18850.1 - 3e-26 92.3 7.4 8.2e-20 71.2 0.4 2.9 4 0 0 4 4 4 2 Dynamin central region MMR_HSR1 PF01926.23 ORY18850.1 - 2.7e-06 27.4 0.2 2.4e-05 24.4 0.2 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF1068 PF06364.12 ORY18850.1 - 0.016 15.1 0.6 0.037 13.9 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1068) Type2_restr_D3 PF16902.5 ORY18850.1 - 0.034 14.1 0.9 1.1 9.2 0.1 3.4 3 0 0 3 3 3 0 Type-2 restriction enzyme D3 domain TRI5 PF06330.11 ORY18850.1 - 0.087 11.7 0.2 1.4 7.7 0.1 2.4 2 0 0 2 2 2 0 Trichodiene synthase (TRI5) KHA PF11834.8 ORY18850.1 - 0.13 12.4 0.0 0.41 10.8 0.0 1.9 1 0 0 1 1 1 0 KHA, dimerisation domain of potassium ion channel AAA_29 PF13555.6 ORY18850.1 - 0.16 11.7 0.0 0.36 10.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_15 PF13175.6 ORY18850.1 - 1.1 8.9 9.9 0.078 12.7 1.5 3.0 2 2 0 2 2 2 0 AAA ATPase domain AMP-binding PF00501.28 ORY18851.1 - 7.4e-64 215.9 0.0 1.2e-63 215.2 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORY18851.1 - 1.3e-05 26.1 0.1 4.7e-05 24.3 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain MmgE_PrpD PF03972.14 ORY18853.1 - 5.3e-144 480.0 0.0 6.5e-144 479.7 0.0 1.1 1 0 0 1 1 1 1 MmgE/PrpD family ARPC4 PF05856.12 ORY18854.1 - 7.4e-78 259.9 3.1 8.8e-78 259.7 3.1 1.1 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) UCH PF00443.29 ORY18855.1 - 5e-52 177.0 0.0 7e-52 176.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 ORY18855.1 - 2e-13 49.9 0.1 3.9e-13 48.9 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin family UCH_1 PF13423.6 ORY18855.1 - 1.3e-12 48.0 4.3 3.1e-11 43.5 4.3 2.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Rad21_Rec8_N PF04825.13 ORY18856.1 - 5.2e-33 113.5 0.0 9.5e-33 112.7 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 ORY18856.1 - 0.02 14.1 0.0 0.062 12.6 0.0 1.8 1 0 0 1 1 1 0 Conserved region of Rad21 / Rec8 like protein DAO PF01266.24 ORY18857.1 - 1.3e-25 90.8 1.4 7.3e-15 55.4 0.3 2.1 1 1 1 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ORY18857.1 - 0.003 17.8 0.1 0.021 15.0 0.1 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 ORY18857.1 - 0.019 14.9 0.0 0.045 13.7 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding Cyt_bd_oxida_II PF02322.15 ORY18857.1 - 0.034 13.5 0.0 0.062 12.7 0.0 1.3 1 0 0 1 1 1 0 Cytochrome bd terminal oxidase subunit II Pyr_redox_2 PF07992.14 ORY18857.1 - 0.073 12.3 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DASH_Hsk3 PF08227.11 ORY18859.1 - 9.5e-19 67.5 1.2 1.6e-18 66.8 1.2 1.4 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like ADIP PF11559.8 ORY18859.1 - 0.0061 16.7 0.1 0.0078 16.3 0.1 1.1 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding FlxA PF14282.6 ORY18859.1 - 0.095 12.7 0.8 0.13 12.3 0.8 1.2 1 0 0 1 1 1 0 FlxA-like protein GATA PF00320.27 ORY18860.1 - 4.5e-16 58.2 2.5 8.5e-16 57.3 2.5 1.5 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.10 ORY18860.1 - 7.1e-13 48.1 1.8 1.3e-12 47.3 1.8 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) DJ-1_PfpI PF01965.24 ORY18861.1 - 1.7e-38 132.0 0.0 2e-38 131.8 0.0 1.0 1 0 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 ORY18861.1 - 0.00055 19.7 0.0 0.048 13.3 0.0 2.2 2 0 0 2 2 2 2 ThiJ/PfpI family-like GATase_3 PF07685.14 ORY18861.1 - 0.00088 18.9 0.0 0.0012 18.5 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain KTI12 PF08433.10 ORY18862.1 - 0.016 14.7 0.0 0.02 14.4 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_18 PF13238.6 ORY18862.1 - 0.024 15.2 0.0 0.075 13.6 0.0 1.7 1 1 1 2 2 2 0 AAA domain AAA_33 PF13671.6 ORY18862.1 - 0.098 12.8 0.1 0.41 10.8 0.1 1.9 1 1 1 2 2 2 0 AAA domain ATPase_2 PF01637.18 ORY18862.1 - 0.12 12.3 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea MMR_HSR1 PF01926.23 ORY18862.1 - 0.14 12.2 0.1 0.28 11.3 0.0 1.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase Radical_SAM PF04055.21 ORY18863.1 - 1.1e-12 48.6 0.2 4.6e-12 46.6 0.1 1.9 1 1 1 2 2 2 1 Radical SAM superfamily Fer4_12 PF13353.6 ORY18863.1 - 3.8e-08 33.7 0.2 7.2e-08 32.8 0.2 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 ORY18863.1 - 7.5e-08 32.5 0.2 1.4e-07 31.7 0.2 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Lipase_GDSL_2 PF13472.6 ORY18864.1 - 6.4e-14 52.7 0.3 1.1e-13 52.0 0.3 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 ORY18864.1 - 1.1e-10 41.8 1.1 2e-10 41.0 1.1 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 ORY18864.1 - 1.8e-05 24.9 0.0 2.9e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family BORCS6 PF10157.9 ORY18865.1 - 0.011 15.9 0.0 0.014 15.7 0.0 1.1 1 0 0 1 1 1 0 BLOC-1-related complex sub-unit 6 COG5 PF10392.9 ORY18865.1 - 0.014 15.6 1.8 0.097 12.8 1.7 2.0 1 1 1 2 2 2 0 Golgi transport complex subunit 5 Not3 PF04065.15 ORY18865.1 - 0.035 13.5 0.3 0.039 13.4 0.3 1.1 1 0 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component DUF2407_C PF13373.6 ORY18865.1 - 0.037 14.2 1.3 0.053 13.7 1.3 1.3 1 1 0 1 1 1 0 DUF2407 C-terminal domain DASH_Dad2 PF08654.10 ORY18865.1 - 0.056 13.9 0.4 0.69 10.4 0.4 2.2 1 1 1 2 2 2 0 DASH complex subunit Dad2 HrpB7 PF09486.10 ORY18865.1 - 0.064 13.6 7.1 0.083 13.3 6.9 1.4 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) BLOC1_2 PF10046.9 ORY18865.1 - 0.089 13.1 0.3 5.3 7.4 0.1 2.4 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Phage_fiber_2 PF03406.13 ORY18867.1 - 6.5 6.4 6.1 10 5.8 2.4 2.1 1 1 1 2 2 2 0 Phage tail fibre repeat TRI12 PF06609.13 ORY18868.1 - 1.6e-33 116.0 27.8 2.2e-33 115.6 27.8 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 ORY18868.1 - 1e-19 70.7 49.5 1e-19 70.7 49.5 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY18868.1 - 6.6e-10 38.4 29.3 1e-08 34.5 12.1 2.6 2 0 0 2 2 2 2 Sugar (and other) transporter Glyco_hydro_45 PF02015.16 ORY18870.1 - 4.4e-54 183.6 13.2 5.1e-54 183.4 13.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 CYTH PF01928.21 ORY18871.1 - 6.8e-07 29.4 0.0 9.2e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 CYTH domain Mpv17_PMP22 PF04117.12 ORY18872.1 - 2.1e-14 53.4 0.6 6.5e-14 51.9 0.6 1.8 1 0 0 1 1 1 1 Mpv17 / PMP22 family DUF2530 PF10745.9 ORY18872.1 - 0.041 14.1 1.3 0.17 12.2 1.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) DUF3341 PF11821.8 ORY18872.1 - 0.75 9.4 4.3 0.36 10.5 2.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3341) Glyco_hydro_16 PF00722.21 ORY18873.1 - 4.1e-15 55.7 0.3 6.8e-15 55.0 0.3 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Glyco_trans_2_3 PF13632.6 ORY18874.1 - 9.5e-52 175.8 2.0 9.5e-52 175.8 2.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 ORY18874.1 - 3.4e-06 27.0 0.0 3e-05 23.9 0.0 2.4 2 1 1 3 3 3 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 ORY18874.1 - 0.0092 15.5 0.0 0.018 14.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 Ala_racemase_N PF01168.20 ORY18875.1 - 2.8e-27 95.8 0.0 3.5e-27 95.5 0.0 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain D-ser_dehydrat PF14031.6 ORY18875.1 - 1.4e-20 73.8 0.0 3e-20 72.7 0.0 1.6 1 0 0 1 1 1 1 Putative serine dehydratase domain LVIVD PF08309.11 ORY18877.1 - 1.9e-06 27.0 0.0 0.13 11.6 0.0 4.9 5 0 0 5 5 5 3 LVIVD repeat tRNA-synt_1c PF00749.21 ORY18917.1 - 7e-96 320.8 0.1 9.1e-94 313.9 0.1 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 ORY18917.1 - 3.6e-30 105.1 0.1 8.6e-30 103.9 0.1 1.7 1 1 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain Methyltransf_10 PF05971.12 ORY18921.1 - 1.3e-52 179.0 0.0 1.8e-52 178.6 0.0 1.1 1 0 0 1 1 1 1 RNA methyltransferase MTS PF05175.14 ORY18921.1 - 2.6e-09 36.8 0.0 7.1e-09 35.4 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain PrmA PF06325.13 ORY18921.1 - 4.5e-05 23.0 0.0 6.7e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 ORY18921.1 - 0.0038 17.0 0.0 0.0065 16.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY18921.1 - 0.0048 17.6 0.0 0.014 16.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 ORY18921.1 - 0.0052 16.7 0.0 0.0095 15.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY18921.1 - 0.0092 16.6 0.0 0.024 15.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain UPF0020 PF01170.18 ORY18921.1 - 0.029 14.0 0.0 0.051 13.3 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_12 PF08242.12 ORY18921.1 - 0.049 14.4 0.0 0.11 13.2 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain AviRa PF11599.8 ORY18921.1 - 0.2 11.1 0.0 0.35 10.3 0.0 1.3 1 0 0 1 1 1 0 RRNA methyltransferase AviRa NAD_binding_7 PF13241.6 ORY18922.1 - 1.7e-33 115.2 0.1 2.4e-33 114.6 0.1 1.2 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 ORY18922.1 - 3.8e-31 106.5 0.0 5.6e-31 106.0 0.0 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.6 ORY18922.1 - 6.2e-15 54.3 0.2 6.2e-15 54.3 0.2 1.8 2 0 0 2 2 2 1 Sirohaem biosynthesis protein central Pyr_redox_3 PF13738.6 ORY18922.1 - 0.00066 19.0 0.0 0.00088 18.6 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase LSDAT_prok PF18171.1 ORY18922.1 - 0.0078 15.5 0.1 0.012 14.9 0.1 1.2 1 0 0 1 1 1 1 SLOG in TRPM, prokaryote AlaDh_PNT_C PF01262.21 ORY18922.1 - 0.017 14.4 0.1 0.022 14.1 0.1 1.1 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.20 ORY18922.1 - 0.021 14.9 0.0 0.035 14.2 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ThiF PF00899.21 ORY18922.1 - 0.025 14.0 0.6 0.12 11.7 0.0 2.0 1 1 1 2 2 2 0 ThiF family DUF5356 PF17309.2 ORY18922.1 - 0.12 12.3 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5356) FYVE PF01363.21 ORY18923.1 - 4.1e-21 74.9 22.4 1.5e-16 60.3 6.7 3.0 3 0 0 3 3 3 2 FYVE zinc finger Rbsn PF11464.8 ORY18923.1 - 2e-19 69.0 0.2 5.9e-19 67.5 0.2 1.9 1 0 0 1 1 1 1 Rabenosyn Rab binding domain zf-Di19 PF05605.12 ORY18923.1 - 8.4e-05 22.8 6.2 0.031 14.6 0.1 2.8 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-AN1 PF01428.16 ORY18923.1 - 0.00058 20.0 0.7 0.00058 20.0 0.7 4.1 4 1 1 5 5 4 1 AN1-like Zinc finger OrsD PF12013.8 ORY18923.1 - 0.012 16.0 0.3 1.7 9.1 0.0 3.4 3 0 0 3 3 3 0 Orsellinic acid/F9775 biosynthesis cluster protein D IBR PF01485.21 ORY18923.1 - 0.03 14.5 0.5 0.03 14.5 0.5 4.0 3 2 1 4 4 4 0 IBR domain, a half RING-finger domain HypA PF01155.19 ORY18923.1 - 0.086 12.9 10.4 0.91 9.6 0.1 3.8 4 0 0 4 4 4 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF4349 PF14257.6 ORY18923.1 - 0.12 11.8 0.5 0.41 10.1 0.5 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) Seryl_tRNA_N PF02403.22 ORY18923.1 - 0.15 12.3 1.3 0.6 10.4 0.3 2.4 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain zf-C2H2_2 PF12756.7 ORY18923.1 - 0.3 11.5 0.0 0.3 11.5 0.0 3.2 3 0 0 3 3 3 0 C2H2 type zinc-finger (2 copies) Rad50_zn_hook PF04423.14 ORY18923.1 - 0.42 10.5 3.0 23 4.9 0.1 4.4 4 0 0 4 4 4 0 Rad50 zinc hook motif ABC_tran_CTD PF16326.5 ORY18923.1 - 0.47 10.7 2.9 9.6 6.5 0.6 3.0 3 1 0 3 3 2 0 ABC transporter C-terminal domain CtIP_N PF10482.9 ORY18923.1 - 0.61 10.1 5.7 5.3 7.1 0.9 3.2 4 0 0 4 4 4 0 Tumour-suppressor protein CtIP N-terminal domain Val_tRNA-synt_C PF10458.9 ORY18923.1 - 0.76 10.1 5.3 6.1 7.2 0.0 3.1 3 0 0 3 3 2 0 Valyl tRNA synthetase tRNA binding arm UBZ_FAAP20 PF15750.5 ORY18923.1 - 0.84 9.6 3.0 5.3 7.1 0.7 3.1 2 0 0 2 2 2 0 Ubiquitin-binding zinc-finger zf-C2H2_4 PF13894.6 ORY18923.1 - 1.4 9.9 0.0 1.4 9.9 0.0 6.2 5 1 1 6 6 6 0 C2H2-type zinc finger zf-C2HC5 PF06221.13 ORY18923.1 - 2 8.5 18.7 0.46 10.5 0.2 4.8 4 1 1 5 5 5 0 Putative zinc finger motif, C2HC5-type TolA_bind_tri PF16331.5 ORY18923.1 - 6.1 7.0 8.9 0.72 10.0 0.1 3.4 4 0 0 4 4 4 0 TolA binding protein trimerisation S1-P1_nuclease PF02265.16 ORY18925.1 - 7.8e-72 242.1 0.0 8.7e-72 242.0 0.0 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease COesterase PF00135.28 ORY18929.1 - 2.3e-70 237.9 0.1 6.6e-57 193.5 0.1 2.7 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 ORY18929.1 - 0.0089 15.9 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold MmgE_PrpD PF03972.14 ORY18930.1 - 1.2e-53 182.3 0.3 1.8e-27 96.0 0.2 2.1 2 0 0 2 2 2 2 MmgE/PrpD family DPBB_1 PF03330.18 ORY18930.1 - 0.068 13.5 0.1 1.2 9.4 0.0 2.5 2 1 1 3 3 3 0 Lytic transglycolase Epimerase PF01370.21 ORY18931.1 - 4.3e-23 82.0 0.0 5.6e-23 81.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ORY18931.1 - 4.9e-15 55.8 0.0 1.3e-14 54.4 0.0 1.6 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 ORY18931.1 - 5.8e-14 51.8 0.0 8.3e-14 51.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 ORY18931.1 - 4.8e-09 35.7 0.0 5.8e-09 35.5 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 ORY18931.1 - 8.2e-09 35.0 0.0 0.00028 20.2 0.0 2.4 1 1 1 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 ORY18931.1 - 3.1e-06 27.2 0.0 1.5e-05 24.9 0.0 1.9 2 0 0 2 2 2 1 NAD(P)H-binding Ldh_1_N PF00056.23 ORY18931.1 - 7.5e-05 22.9 0.0 0.00014 22.0 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain NmrA PF05368.13 ORY18931.1 - 9.3e-05 22.1 0.0 0.0044 16.6 0.0 2.1 2 0 0 2 2 2 1 NmrA-like family KR PF08659.10 ORY18931.1 - 0.00043 20.2 0.0 0.0012 18.8 0.0 1.8 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 ORY18931.1 - 0.0079 15.4 0.0 0.31 10.1 0.0 2.1 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.25 ORY18931.1 - 0.014 14.8 0.0 0.06 12.8 0.0 2.0 1 1 0 1 1 1 0 short chain dehydrogenase Semialdhyde_dh PF01118.24 ORY18931.1 - 0.029 14.8 0.0 0.069 13.6 0.0 1.7 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 ORY18931.1 - 0.1 12.7 0.0 0.28 11.3 0.0 1.8 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Cbl_N3 PF02762.14 ORY18931.1 - 0.14 12.0 0.0 1.3 8.9 0.0 2.4 3 0 0 3 3 3 0 CBL proto-oncogene N-terminus, SH2-like domain TRI12 PF06609.13 ORY18932.1 - 9.8e-64 215.8 19.0 1.1e-63 215.6 19.0 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 ORY18932.1 - 1.1e-17 64.1 72.8 1.8e-17 63.4 64.1 3.2 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY18932.1 - 4.3e-12 45.6 2.5 4.3e-12 45.6 2.5 3.3 2 1 1 3 3 3 2 Sugar (and other) transporter GFA PF04828.14 ORY18934.1 - 0.001 19.4 0.4 0.001 19.4 0.4 2.1 3 1 1 4 4 4 1 Glutathione-dependent formaldehyde-activating enzyme CEBP_ZZ PF16366.5 ORY18934.1 - 0.0084 16.3 1.6 0.016 15.4 1.6 1.4 1 0 0 1 1 1 1 Cytoplasmic polyadenylation element-binding protein ZZ domain Abhydrolase_6 PF12697.7 ORY18935.1 - 1.9e-11 45.0 0.3 3.1e-11 44.3 0.2 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORY18935.1 - 7.1e-09 35.3 0.0 1.2e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ORY18935.1 - 8.3e-08 32.2 0.1 1.7e-07 31.2 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 ORY18935.1 - 5.3e-05 23.2 0.1 0.00013 21.9 0.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Lipase_3 PF01764.25 ORY18935.1 - 0.033 14.1 0.6 0.32 10.9 0.3 2.2 1 1 1 2 2 2 0 Lipase (class 3) Abhydrolase_5 PF12695.7 ORY18935.1 - 0.033 13.9 0.2 0.16 11.7 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase family Ser_hydrolase PF06821.13 ORY18935.1 - 0.089 12.6 0.0 0.52 10.2 0.0 2.1 1 1 0 1 1 1 0 Serine hydrolase Lipase PF00151.19 ORY18935.1 - 0.11 11.7 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Lipase PGAP1 PF07819.13 ORY18935.1 - 0.16 11.7 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein DUF900 PF05990.12 ORY18935.1 - 0.22 11.0 0.0 1.1 8.7 0.0 2.0 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) FAD_binding_3 PF01494.19 ORY18936.1 - 1.5e-09 37.6 0.1 0.0093 15.2 0.0 3.1 3 0 0 3 3 3 2 FAD binding domain Pyr_redox PF00070.27 ORY18936.1 - 0.035 14.6 0.1 0.1 13.1 0.1 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ORY18936.1 - 0.053 12.8 0.4 1 8.6 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORY18936.1 - 0.079 13.2 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 ORY18936.1 - 0.13 11.6 0.0 2.6 7.2 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase SKG6 PF08693.10 ORY18936.1 - 3.2 7.2 6.2 7.2 6.1 6.2 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Tet_JBP PF12851.7 ORY18937.1 - 0.02 14.3 0.0 0.28 10.5 0.0 2.0 2 0 0 2 2 2 0 Oxygenase domain of the 2OGFeDO superfamily F-box-like_2 PF13013.6 ORY18937.1 - 0.03 14.3 0.0 0.076 13.0 0.0 1.8 2 0 0 2 2 2 0 F-box-like domain NMU PF02070.15 ORY18939.1 - 0.4 10.6 0.2 0.4 10.6 0.2 2.2 3 0 0 3 3 3 0 Neuromedin U Ank_2 PF12796.7 ORY18940.1 - 4.6e-28 97.6 2.3 3.2e-12 46.9 0.2 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ORY18940.1 - 8.2e-15 53.5 0.9 0.0035 17.7 0.0 5.2 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.6 ORY18940.1 - 2.1e-13 50.5 0.2 1.5e-05 25.5 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 ORY18940.1 - 6.1e-12 45.5 1.0 0.027 14.8 0.0 5.2 3 1 3 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.30 ORY18940.1 - 1.2e-10 41.4 3.7 0.024 15.1 0.0 4.9 4 0 0 4 4 4 3 Ankyrin repeat FliT PF05400.13 ORY18940.1 - 0.029 15.2 1.6 3.6 8.5 0.1 3.6 3 1 1 4 4 4 0 Flagellar protein FliT Ank_2 PF12796.7 ORY18941.1 - 3.4e-10 40.4 0.0 0.00011 22.7 0.0 4.0 2 1 3 5 5 5 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY18941.1 - 4.1e-08 33.6 0.0 0.037 14.6 0.0 5.4 5 0 0 5 5 5 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 ORY18941.1 - 5.3e-07 29.8 0.0 0.00022 21.5 0.0 4.2 3 2 0 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 ORY18941.1 - 1.8e-05 25.0 0.6 1.1 9.8 0.0 5.2 4 1 1 5 5 5 2 Ankyrin repeat Ank_3 PF13606.6 ORY18941.1 - 0.0068 16.8 1.0 2.1 9.2 0.0 5.3 6 0 0 6 6 6 1 Ankyrin repeat Sulfotransfer_4 PF17784.1 ORY18942.1 - 3.2e-58 197.1 0.1 3.7e-58 196.9 0.1 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 ORY18942.1 - 0.00054 20.4 1.3 0.099 13.0 0.0 2.5 1 1 1 2 2 2 2 Sulfotransferase family AAA_18 PF13238.6 ORY18942.1 - 0.18 12.4 0.0 0.41 11.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain SET PF00856.28 ORY18943.1 - 2.6e-14 54.0 0.0 1.4e-13 51.6 0.0 2.2 2 1 0 2 2 2 1 SET domain TPP_enzyme_N PF02776.18 ORY18944.1 - 2e-37 128.5 0.0 1.3e-36 125.8 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 ORY18944.1 - 2.1e-19 69.8 0.0 4.4e-19 68.8 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 ORY18944.1 - 1.3e-10 41.2 0.0 4e-10 39.6 0.0 1.8 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain HET PF06985.11 ORY18945.1 - 9.1e-18 65.0 0.0 9.9e-18 64.9 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) RicinB_lectin_2 PF14200.6 ORY18948.1 - 0.00065 20.4 0.1 0.024 15.4 0.1 2.5 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Iso_dh PF00180.20 ORY18949.1 - 3.6e-100 335.5 0.0 4.5e-100 335.2 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Phage_30_3 PF08010.11 ORY18949.1 - 0.014 15.2 0.0 0.03 14.1 0.0 1.5 1 0 0 1 1 1 0 Bacteriophage protein GP30.3 HHH_2 PF12826.7 ORY18949.1 - 0.036 14.1 0.1 0.64 10.2 0.0 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix motif Peptidase_S24 PF00717.23 ORY18950.1 - 6.6e-05 22.8 0.9 0.00029 20.7 0.9 1.9 1 1 0 1 1 1 1 Peptidase S24-like Iso_dh PF00180.20 ORY18951.1 - 7.9e-91 304.8 0.0 9.3e-91 304.5 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase GLTP PF08718.11 ORY18952.1 - 2.7e-47 160.8 0.0 3.9e-47 160.3 0.0 1.2 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) Methyltransf_32 PF13679.6 ORY18953.1 - 0.058 13.4 0.0 0.099 12.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Pirin PF02678.16 ORY18955.1 - 7.1e-28 96.7 0.2 1.3e-27 95.9 0.2 1.4 1 0 0 1 1 1 1 Pirin Pirin_C_2 PF17954.1 ORY18955.1 - 9.3e-05 22.5 0.0 0.00037 20.6 0.0 2.0 1 1 0 1 1 1 1 Quercetinase C-terminal cupin domain Cupin_2 PF07883.11 ORY18955.1 - 0.00044 19.9 0.9 0.026 14.3 0.2 2.8 3 1 0 3 3 3 1 Cupin domain WHAMM-JMY_N PF15920.5 ORY18957.1 - 0.13 12.2 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 N-terminal of Junction-mediating and WASP homolog-associated ALMS_repeat PF18727.1 ORY18958.1 - 0.11 12.4 2.6 0.36 10.7 0.5 2.3 2 0 0 2 2 2 0 Alstrom syndrome repeat Abhydrolase_6 PF12697.7 ORY18959.1 - 4e-14 53.8 1.4 5.1e-14 53.4 1.4 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORY18959.1 - 2.2e-10 40.2 0.0 3.3e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ORY18959.1 - 1.1e-06 28.5 0.1 1.9e-06 27.7 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold LIP PF03583.14 ORY18959.1 - 0.00016 21.1 2.6 0.00025 20.5 2.6 1.2 1 0 0 1 1 1 1 Secretory lipase Peptidase_S9 PF00326.21 ORY18959.1 - 0.0069 15.9 0.2 0.9 9.0 0.2 2.4 2 0 0 2 2 2 1 Prolyl oligopeptidase family DUF676 PF05057.14 ORY18959.1 - 0.017 14.6 0.2 0.026 14.1 0.2 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Abhydrolase_8 PF06259.12 ORY18959.1 - 0.04 13.5 0.1 0.066 12.8 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase Peptidase_S28 PF05577.12 ORY18959.1 - 0.052 12.3 0.2 0.078 11.8 0.2 1.2 1 0 0 1 1 1 0 Serine carboxypeptidase S28 LIDHydrolase PF10230.9 ORY18959.1 - 0.063 12.8 0.0 0.099 12.2 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase PGAP1 PF07819.13 ORY18959.1 - 0.12 12.1 0.2 0.34 10.6 0.3 1.6 2 0 0 2 2 2 0 PGAP1-like protein Cupin_1 PF00190.22 ORY18960.1 - 1.1e-12 47.8 0.7 1.7e-12 47.2 0.7 1.2 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.11 ORY18960.1 - 0.069 12.9 0.0 1.2 8.9 0.0 2.3 2 0 0 2 2 2 0 Cupin domain NmrA PF05368.13 ORY18961.1 - 4.6e-55 186.7 0.0 5.5e-55 186.4 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ORY18961.1 - 1.7e-12 47.6 0.0 2.3e-12 47.2 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 ORY18961.1 - 0.0018 17.4 0.0 0.0029 16.7 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 ORY18961.1 - 0.04 13.4 0.0 0.087 12.3 0.0 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family CFEM PF05730.11 ORY18965.1 - 9.5e-11 41.6 11.6 1.8e-10 40.8 11.6 1.4 1 0 0 1 1 1 1 CFEM domain Methyltransf_2 PF00891.18 ORY18967.1 - 3.4e-24 85.3 0.0 5.4e-24 84.7 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 ORY18967.1 - 0.00058 19.8 0.0 0.0012 18.8 0.0 1.4 1 0 0 1 1 1 1 Dimerisation domain adh_short_C2 PF13561.6 ORY18970.1 - 2.3e-35 122.3 0.3 2.1e-33 115.8 0.3 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY18970.1 - 6.3e-19 68.2 0.4 1.5e-16 60.4 0.4 2.2 1 1 0 1 1 1 1 short chain dehydrogenase Yip1 PF04893.17 ORY18972.1 - 0.047 13.4 0.1 0.06 13.1 0.1 1.1 1 0 0 1 1 1 0 Yip1 domain CFEM PF05730.11 ORY18974.1 - 9.4e-05 22.4 0.2 0.00015 21.8 0.2 1.3 1 0 0 1 1 1 1 CFEM domain PhyH PF05721.13 ORY18976.1 - 6e-12 46.3 0.0 1e-11 45.5 0.0 1.4 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) MFS_1 PF07690.16 ORY18979.1 - 7.8e-07 28.3 6.9 1.1e-06 27.9 6.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DIOX_N PF14226.6 ORY18980.1 - 1.8e-28 99.7 0.0 2.8e-28 99.1 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 ORY18980.1 - 4.3e-18 65.7 0.0 7.1e-18 65.0 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily NYN PF01936.18 ORY18982.1 - 1.7e-11 44.8 0.1 2.5e-11 44.2 0.1 1.2 1 0 0 1 1 1 1 NYN domain zf-CCCH_2 PF14608.6 ORY18982.1 - 0.072 13.6 11.9 0.11 13.0 5.0 2.5 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Pyrophosphatase PF00719.19 ORY18986.1 - 0.094 12.5 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Inorganic pyrophosphatase Glycos_transf_1 PF00534.20 ORY18988.1 - 1.7e-14 53.7 0.0 3.3e-14 52.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 ORY18988.1 - 9.6e-13 48.7 0.0 2e-12 47.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF3492 PF11997.8 ORY18988.1 - 0.00039 20.3 0.0 0.00085 19.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3492) Glyco_trans_1_2 PF13524.6 ORY18988.1 - 0.12 12.8 0.0 0.53 10.7 0.0 2.1 1 1 0 1 1 1 0 Glycosyl transferases group 1 Spherulin4 PF12138.8 ORY18989.1 - 1.6e-70 237.5 4.2 1.9e-70 237.3 4.2 1.0 1 0 0 1 1 1 1 Spherulation-specific family 4 DUF5501 PF17605.2 ORY18989.1 - 0.072 13.5 0.3 0.16 12.4 0.3 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5501) DUF5532 PF17673.1 ORY18989.1 - 0.19 11.8 0.0 0.47 10.5 0.0 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5532) Spherulin4 PF12138.8 ORY18990.1 - 5.5e-58 196.4 0.0 6.2e-58 196.3 0.0 1.0 1 0 0 1 1 1 1 Spherulation-specific family 4 DUF3873 PF12989.7 ORY18990.1 - 0.16 12.3 0.0 0.31 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3873) Epimerase PF01370.21 ORY18991.1 - 7.2e-34 117.3 0.1 2.2e-32 112.5 0.1 3.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ORY18991.1 - 2.8e-32 112.4 0.0 8.2e-31 107.6 0.0 2.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 ORY18991.1 - 3.4e-05 23.0 0.9 0.23 10.4 0.0 2.7 2 1 1 3 3 3 2 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 ORY18991.1 - 3.6e-05 23.1 0.0 0.0018 17.5 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein Polysacc_synt_2 PF02719.15 ORY18991.1 - 0.0013 18.0 0.0 0.16 11.0 0.1 3.3 2 1 0 3 3 3 1 Polysaccharide biosynthesis protein KR PF08659.10 ORY18991.1 - 0.012 15.5 0.1 0.076 12.9 0.1 2.0 1 1 0 1 1 1 0 KR domain adh_short PF00106.25 ORY18991.1 - 0.065 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase CorA PF01544.18 ORY18992.1 - 2.4e-07 30.4 3.0 3.6e-07 29.8 3.0 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein PAN_2 PF08276.11 ORY18993.1 - 0.026 14.6 1.6 0.036 14.2 0.2 2.0 2 0 0 2 2 2 0 PAN-like domain Nop53 PF07767.11 ORY18994.1 - 2.1e-99 333.6 32.0 2.5e-99 333.4 32.0 1.1 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) FtsA PF14450.6 ORY18994.1 - 0.044 14.2 0.7 5.9 7.4 1.2 2.4 2 0 0 2 2 2 0 Cell division protein FtsA RR_TM4-6 PF06459.12 ORY18994.1 - 6.5 6.5 19.4 13 5.5 19.4 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Ras PF00071.22 ORY18995.1 - 1.1e-59 200.7 0.4 1.3e-59 200.4 0.4 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY18995.1 - 5.1e-37 126.7 0.2 9.2e-37 125.9 0.2 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY18995.1 - 1.2e-17 63.9 0.3 1.6e-17 63.5 0.3 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 ORY18995.1 - 1.7e-06 27.7 0.1 2.6e-05 23.9 0.1 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 ORY18995.1 - 4.4e-06 26.2 0.1 6.1e-06 25.8 0.1 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 ORY18995.1 - 1.2e-05 25.2 0.3 0.0076 16.2 0.2 2.3 2 1 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 ORY18995.1 - 1.7e-05 24.8 0.1 3e-05 24.1 0.1 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 ORY18995.1 - 2.7e-05 23.6 0.2 3.5e-05 23.3 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_7 PF12775.7 ORY18995.1 - 0.095 12.2 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_28 PF13521.6 ORY18995.1 - 0.097 12.9 0.0 11 6.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain MAS20 PF02064.15 ORY18996.1 - 3.1e-47 159.9 5.6 2.6e-45 153.6 5.6 2.0 1 1 0 1 1 1 1 MAS20 protein import receptor Nif11 PF07862.11 ORY18996.1 - 0.054 13.8 2.3 0.4 11.0 1.4 2.6 1 1 0 2 2 2 0 Nif11 domain Frankia_peptide PF14407.6 ORY18996.1 - 0.055 13.5 2.0 6 6.9 0.4 2.3 2 0 0 2 2 2 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. ORC_WH_C PF18137.1 ORY18996.1 - 0.25 11.4 3.4 0.26 11.3 2.1 1.7 2 0 0 2 2 2 0 Origin recognition complex winged helix C-terminal Exo84_C PF16528.5 ORY18997.1 - 2.4e-70 236.5 3.8 2.4e-70 236.5 3.8 2.2 3 0 0 3 3 3 1 Exocyst component 84 C-terminal Vps51 PF08700.11 ORY18997.1 - 8.7e-18 64.2 1.3 3.1e-17 62.4 1.3 2.0 1 0 0 1 1 1 1 Vps51/Vps67 COG2 PF06148.11 ORY18997.1 - 0.0064 16.6 1.7 0.056 13.5 0.0 2.7 2 1 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Halogen_Hydrol PF10112.9 ORY18997.1 - 0.14 12.1 5.0 0.87 9.6 0.4 2.6 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein UPF0242 PF06785.11 ORY18997.1 - 1.3 9.1 6.8 1.1 9.4 0.5 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Atg29_N PF18388.1 ORY18998.1 - 0.0078 16.0 0.1 4.2 7.3 0.0 2.3 2 0 0 2 2 2 2 Atg29 N-terminal domain HTH_AsnC-type PF13404.6 ORY18998.1 - 0.019 14.8 0.0 1.6 8.6 0.0 2.2 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain RNase_PH PF01138.21 ORY18999.1 - 4.8e-25 88.6 0.0 7.2e-25 88.0 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Anp1 PF03452.14 ORY19000.1 - 1.4e-113 378.7 0.2 2.6e-113 377.8 0.0 1.5 2 0 0 2 2 2 1 Anp1 Rad54_N PF08658.10 ORY19000.1 - 0.024 14.8 1.9 0.047 13.8 1.9 1.5 1 0 0 1 1 1 0 Rad54 N terminal MARVEL PF01284.23 ORY19002.1 - 0.083 12.9 7.3 0.12 12.4 6.1 1.8 1 1 1 2 2 2 0 Membrane-associating domain TEX29 PF15839.5 ORY19002.1 - 0.57 10.8 4.5 0.41 11.3 0.8 2.4 2 1 0 2 2 2 0 Testis-expressed sequence 29 protein GCP_N_terminal PF17681.1 ORY19003.1 - 1e-29 104.1 0.0 1.8e-29 103.4 0.0 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 ORY19003.1 - 9.3e-24 84.4 0.0 1.8e-23 83.5 0.0 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal BATS PF06968.13 ORY19004.1 - 2.8e-22 78.7 0.1 9.8e-22 76.9 0.0 1.9 2 0 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 ORY19004.1 - 5.9e-15 56.0 0.3 3.8e-14 53.4 0.2 2.0 2 0 0 2 2 2 1 Radical SAM superfamily Aminotran_1_2 PF00155.21 ORY19005.1 - 4.4e-35 121.5 0.0 5.2e-35 121.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 ORY19005.1 - 0.029 13.3 0.0 0.3 10.0 0.0 2.1 2 0 0 2 2 2 0 Aminotransferase class-V Aminotran_3 PF00202.21 ORY19006.1 - 1.3e-36 126.2 0.0 3.4e-21 75.4 0.0 3.3 2 1 0 2 2 2 2 Aminotransferase class-III AAA_26 PF13500.6 ORY19006.1 - 2.2e-16 60.3 0.0 3.8e-16 59.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain LAL_C2 PF18603.1 ORY19006.1 - 0.11 12.6 0.1 0.26 11.5 0.1 1.5 1 0 0 1 1 1 0 L-amino acid ligase C-terminal domain 2 Ras PF00071.22 ORY19007.1 - 2.8e-48 163.6 0.0 3.9e-48 163.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY19007.1 - 9.4e-20 71.0 0.0 1.4e-19 70.5 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY19007.1 - 4.1e-05 23.1 0.0 8.4e-05 22.1 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family AAA_7 PF12775.7 ORY19007.1 - 0.13 11.7 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region PAP2 PF01569.21 ORY19008.1 - 6.3e-17 61.6 5.4 1.6e-16 60.3 5.4 1.7 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 ORY19008.1 - 0.0032 17.2 8.0 0.0072 16.0 8.0 1.7 1 1 0 1 1 1 1 PAP2 superfamily EF-hand_6 PF13405.6 ORY19009.1 - 4e-08 32.6 0.9 0.0058 16.5 0.0 2.8 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 ORY19009.1 - 4.2e-05 22.8 0.0 0.00013 21.3 0.0 1.8 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 ORY19009.1 - 8e-05 23.0 0.3 0.012 16.0 0.1 2.0 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 ORY19009.1 - 0.0059 16.1 0.0 0.012 15.1 0.0 1.5 1 0 0 1 1 1 1 EF hand Met_10 PF02475.16 ORY19010.1 - 1.9e-07 31.0 0.0 3.4e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein MTS PF05175.14 ORY19010.1 - 0.014 15.0 0.0 0.023 14.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain DUF4743 PF15916.5 ORY19011.1 - 8e-13 48.4 0.0 1.2e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4743) NUDIX PF00293.28 ORY19011.1 - 1.5e-08 34.8 0.1 2.6e-08 34.0 0.1 1.4 1 0 0 1 1 1 1 NUDIX domain PHB_depo_C PF06850.11 ORY19011.1 - 0.016 14.7 0.0 0.035 13.6 0.0 1.5 1 0 0 1 1 1 0 PHB de-polymerase C-terminus RNA_pol_Rpb8 PF03870.15 ORY19012.1 - 6.8e-45 152.7 0.1 7.6e-45 152.5 0.1 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 RNA_pol_RpbG PF16992.5 ORY19012.1 - 2.5e-05 24.3 1.0 0.0061 16.6 1.0 2.0 1 1 0 1 1 1 1 DNA-directed RNA polymerase, subunit G PAXNEB PF05625.11 ORY19014.1 - 1e-109 367.1 0.0 1.2e-109 366.9 0.0 1.0 1 0 0 1 1 1 1 PAXNEB protein tRNA_int_endo PF01974.17 ORY19015.1 - 4.9e-14 52.2 0.0 1e-13 51.2 0.0 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain DASH_Dad1 PF08649.10 ORY19016.1 - 6.8e-26 90.2 3.2 8.2e-26 90.0 3.2 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad1 DASH_Dad4 PF08650.10 ORY19016.1 - 0.02 14.9 0.3 0.027 14.4 0.3 1.1 1 0 0 1 1 1 0 DASH complex subunit Dad4 Cation_ATPase_C PF00689.21 ORY19018.1 - 1.1e-47 162.1 7.9 1.1e-47 162.1 7.9 2.8 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 ORY19018.1 - 1.7e-38 131.9 0.5 1.7e-38 131.9 0.5 3.0 4 0 0 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 ORY19018.1 - 1.7e-20 74.3 0.0 6.2e-20 72.4 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 ORY19018.1 - 7.4e-19 67.6 0.0 1.5e-18 66.7 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 ORY19018.1 - 1.3e-07 31.2 0.2 6.5e-07 28.9 0.0 2.3 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 ORY19018.1 - 6.6e-06 26.0 0.1 2.8e-05 24.0 0.1 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase RskA PF10099.9 ORY19018.1 - 0.00032 21.1 0.5 1.2 9.4 0.1 3.9 3 1 0 3 3 3 2 Anti-sigma-K factor rskA LptF_LptG PF03739.14 ORY19018.1 - 0.0026 16.7 2.4 0.0058 15.5 1.8 1.8 2 0 0 2 2 2 1 Lipopolysaccharide export system permease LptF/LptG MatE PF01554.18 ORY19018.1 - 1.4 8.5 6.8 0.12 12.1 0.7 2.4 2 1 0 2 2 2 0 MatE TctB PF07331.11 ORY19018.1 - 3 8.1 9.2 1.7 8.9 1.0 3.0 3 0 0 3 3 3 0 Tripartite tricarboxylate transporter TctB family EMP70 PF02990.16 ORY19019.1 - 0.0056 15.4 0.0 0.0071 15.1 0.0 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 CorA PF01544.18 ORY19019.1 - 0.015 14.6 2.0 0.035 13.4 2.0 1.5 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein TPR_2 PF07719.17 ORY19020.1 - 1.9e-11 43.2 1.4 0.025 14.7 0.0 5.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 ORY19020.1 - 1.4e-09 37.3 0.1 0.18 11.7 0.0 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 ORY19020.1 - 2e-05 24.2 2.0 0.023 14.4 0.2 4.2 5 0 0 5 5 5 1 TPR repeat TPR_8 PF13181.6 ORY19020.1 - 2.2e-05 24.3 0.7 0.55 10.6 0.1 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 ORY19020.1 - 4.8e-05 23.6 2.8 0.0068 16.7 0.4 4.7 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_4 PF07721.14 ORY19020.1 - 0.00072 20.0 4.0 0.63 10.8 1.2 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 ORY19020.1 - 0.0011 18.8 0.3 7.2 6.9 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 ORY19020.1 - 0.0085 16.7 2.1 31 5.3 0.2 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 ORY19020.1 - 0.017 15.9 6.0 53 5.0 0.1 7.0 8 0 0 8 8 8 0 Tetratricopeptide repeat Oxysterol_BP PF01237.18 ORY19022.1 - 4.2e-57 193.7 0.0 1.6e-54 185.1 0.0 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein HD PF01966.22 ORY19023.1 - 1.6e-09 38.1 0.1 2.3e-09 37.5 0.1 1.2 1 0 0 1 1 1 1 HD domain Sulfotransfer_4 PF17784.1 ORY19024.1 - 1e-71 241.2 0.0 1.2e-71 241.0 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 ORY19024.1 - 0.0022 18.4 0.3 0.27 11.6 0.0 2.7 1 1 1 2 2 2 2 Sulfotransferase family Glyco_hydro_125 PF06824.11 ORY19025.1 - 5.7e-177 588.8 0.0 6.6e-177 588.5 0.0 1.0 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) UPF0086 PF01868.16 ORY19027.1 - 1.2e-27 95.7 0.1 1.6e-27 95.2 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function UPF0086 ABC_tran PF00005.27 ORY19028.1 - 1.2e-49 168.3 1.1 1.2e-27 97.1 0.0 3.1 3 0 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 ORY19028.1 - 3.2e-23 83.0 2.6 3.2e-06 27.2 0.0 4.8 3 2 2 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 ORY19028.1 - 4.4e-19 68.8 48.2 7e-14 51.7 23.6 2.4 3 0 0 3 3 3 2 ABC-2 family transporter protein SMC_N PF02463.19 ORY19028.1 - 2.4e-07 30.4 2.2 0.091 12.2 0.1 4.1 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 ORY19028.1 - 1e-06 28.8 1.3 0.0045 16.9 0.3 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 ORY19028.1 - 2.4e-06 28.2 2.3 0.019 15.4 0.2 2.5 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 ORY19028.1 - 7.9e-06 25.8 0.3 0.0099 15.6 0.2 3.2 3 0 0 3 3 3 1 AAA ATPase domain AAA_29 PF13555.6 ORY19028.1 - 8.8e-06 25.4 3.1 0.048 13.4 0.5 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC2_membrane PF01061.24 ORY19028.1 - 1.1e-05 24.9 19.3 1.1e-05 24.9 19.3 4.9 4 1 1 5 5 4 1 ABC-2 type transporter AAA_27 PF13514.6 ORY19028.1 - 3.2e-05 23.6 0.2 0.19 11.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain Rad17 PF03215.15 ORY19028.1 - 0.00041 20.3 0.0 0.2 11.6 0.0 2.7 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_22 PF13401.6 ORY19028.1 - 0.0011 19.3 0.8 1.7 8.9 0.3 2.7 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 ORY19028.1 - 0.0016 18.8 1.0 1.6 9.1 0.2 2.5 2 0 0 2 2 2 2 AAA ATPase domain Zeta_toxin PF06414.12 ORY19028.1 - 0.008 15.5 2.6 1.4 8.1 0.1 2.3 2 0 0 2 2 2 2 Zeta toxin AAA_30 PF13604.6 ORY19028.1 - 0.016 14.9 10.0 0.67 9.6 0.8 3.4 2 1 1 3 3 3 0 AAA domain DUF4162 PF13732.6 ORY19028.1 - 0.03 15.0 0.1 0.14 12.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4162) NB-ARC PF00931.22 ORY19028.1 - 0.031 13.5 0.4 11 5.1 0.1 3.1 2 1 0 2 2 2 0 NB-ARC domain SRP54 PF00448.22 ORY19028.1 - 0.048 13.3 3.7 3.1 7.4 0.1 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA PF00004.29 ORY19028.1 - 0.06 13.8 0.2 3.2 8.2 0.1 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 ORY19028.1 - 0.08 13.3 0.2 6.1 7.3 0.0 2.7 2 0 0 2 2 2 0 RNA helicase ATP-synt_ab PF00006.25 ORY19028.1 - 0.16 11.6 0.4 0.6 9.7 0.0 2.0 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain SbcCD_C PF13558.6 ORY19028.1 - 0.17 12.1 0.1 19 5.6 0.0 3.6 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AIG1 PF04548.16 ORY19028.1 - 0.25 10.6 3.5 0.54 9.5 1.0 2.2 2 0 0 2 2 2 0 AIG1 family AAA_28 PF13521.6 ORY19028.1 - 0.28 11.4 4.6 0.99 9.6 1.6 2.4 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 ORY19028.1 - 0.28 11.3 3.7 5.4 7.1 1.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_33 PF13671.6 ORY19028.1 - 0.32 11.1 1.5 30 4.8 0.2 2.7 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 ORY19028.1 - 0.41 9.7 1.8 5.5 6.0 0.3 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_25 PF13481.6 ORY19028.1 - 0.48 10.0 4.0 19 4.8 0.3 3.2 3 0 0 3 3 3 0 AAA domain PNP_phzG_C PF10590.9 ORY19029.1 - 2.8e-22 78.5 1.6 9.6e-22 76.8 1.6 2.0 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Putative_PNPOx PF01243.20 ORY19029.1 - 1e-17 64.1 0.0 1.7e-17 63.3 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxase_2 PF12766.7 ORY19029.1 - 0.00073 20.1 0.3 0.0014 19.2 0.3 1.5 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Imm74 PF15603.6 ORY19029.1 - 0.0069 16.5 0.0 0.1 12.8 0.0 2.5 3 0 0 3 3 3 1 Immunity protein 74 Gly_transf_sug PF04488.15 ORY19030.1 - 1.1e-11 45.2 0.2 3.1e-11 43.8 0.1 1.8 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 ORY19030.1 - 0.12 11.8 0.1 0.22 10.9 0.1 1.5 1 1 0 1 1 1 0 Capsular polysaccharide synthesis protein DUF4121 PF13497.6 ORY19030.1 - 0.16 11.1 0.5 0.34 10.0 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4121) Acyl_transf_3 PF01757.22 ORY19031.1 - 3.6e-33 115.0 32.0 4.6e-33 114.7 32.0 1.1 1 0 0 1 1 1 1 Acyltransferase family PSCyt3 PF07627.11 ORY19034.1 - 0.033 14.4 0.3 0.12 12.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1588) AAA PF00004.29 ORY19035.1 - 9.6e-91 301.1 0.0 2.3e-45 154.3 0.0 2.6 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 ORY19035.1 - 2.5e-18 65.6 1.1 7.5e-09 35.3 0.1 2.8 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 ORY19035.1 - 8e-13 49.1 3.2 8.5e-05 23.0 0.0 4.6 2 2 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 ORY19035.1 - 2e-12 47.5 2.8 0.0036 17.6 0.0 5.3 2 2 3 5 5 5 3 AAA domain RuvB_N PF05496.12 ORY19035.1 - 1.3e-11 44.5 0.0 0.0002 21.1 0.0 2.7 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 ORY19035.1 - 1e-10 41.7 0.1 0.00083 19.4 0.0 3.5 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 ORY19035.1 - 2.5e-09 37.5 0.0 0.00062 19.9 0.0 3.2 3 1 0 3 3 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 ORY19035.1 - 1.4e-08 35.0 0.0 0.0058 16.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.13 ORY19035.1 - 3.6e-08 33.0 0.0 0.0015 17.8 0.0 2.6 2 1 1 3 3 3 2 TIP49 P-loop domain AAA_18 PF13238.6 ORY19035.1 - 2.1e-07 31.6 0.0 0.015 15.8 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_14 PF13173.6 ORY19035.1 - 5.9e-07 29.6 0.0 0.029 14.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 ORY19035.1 - 7e-07 29.6 0.0 0.036 14.4 0.0 2.5 2 0 0 2 2 2 2 RNA helicase Rad17 PF03215.15 ORY19035.1 - 9.4e-07 28.9 0.0 0.005 16.8 0.0 2.4 2 0 0 2 2 2 2 Rad17 P-loop domain TsaE PF02367.17 ORY19035.1 - 9.8e-07 28.8 0.0 0.035 14.1 0.0 2.8 3 0 0 3 3 3 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 ORY19035.1 - 1e-06 28.2 0.1 0.052 12.8 0.0 3.3 3 0 0 3 3 3 2 Zeta toxin AAA_28 PF13521.6 ORY19035.1 - 1.1e-06 29.0 0.0 0.037 14.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.6 ORY19035.1 - 3.7e-06 27.4 0.0 0.015 15.7 0.0 3.2 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 ORY19035.1 - 4.1e-06 26.3 0.1 0.025 14.0 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 ORY19035.1 - 1.1e-05 25.3 0.0 0.064 13.0 0.1 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_3 PF07726.11 ORY19035.1 - 1.3e-05 25.1 0.0 0.029 14.2 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 ORY19035.1 - 1.3e-05 24.6 0.4 0.055 12.8 0.0 3.0 4 0 0 4 4 3 2 KaiC AAA_25 PF13481.6 ORY19035.1 - 5.3e-05 22.9 0.6 1.2 8.7 0.0 3.7 3 1 1 4 4 3 2 AAA domain ABC_tran PF00005.27 ORY19035.1 - 6.3e-05 23.5 0.0 0.22 12.0 0.0 3.2 3 0 0 3 3 3 1 ABC transporter AAA_7 PF12775.7 ORY19035.1 - 8.1e-05 22.2 0.1 0.29 10.6 0.0 2.9 2 1 0 2 2 2 2 P-loop containing dynein motor region DUF815 PF05673.13 ORY19035.1 - 9.9e-05 21.6 0.0 0.02 14.1 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) NACHT PF05729.12 ORY19035.1 - 0.00012 22.1 0.2 1.1 9.2 0.0 3.3 3 0 0 3 3 3 2 NACHT domain Cytidylate_kin2 PF13189.6 ORY19035.1 - 0.0003 21.0 0.0 0.057 13.6 0.0 2.6 2 0 0 2 2 2 1 Cytidylate kinase-like family AAA_11 PF13086.6 ORY19035.1 - 0.00039 20.3 0.6 1.2 8.8 0.0 3.1 3 0 0 3 3 3 2 AAA domain Sigma54_activat PF00158.26 ORY19035.1 - 0.00063 19.5 0.0 0.21 11.3 0.0 2.7 2 0 0 2 2 2 1 Sigma-54 interaction domain Viral_helicase1 PF01443.18 ORY19035.1 - 0.0009 19.0 0.0 0.66 9.7 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase SKI PF01202.22 ORY19035.1 - 0.00095 19.3 0.0 0.45 10.6 0.0 2.7 2 0 0 2 2 2 1 Shikimate kinase TniB PF05621.11 ORY19035.1 - 0.0027 17.1 0.0 0.59 9.5 0.0 3.0 3 0 0 3 3 3 1 Bacterial TniB protein AAA_24 PF13479.6 ORY19035.1 - 0.0028 17.4 0.0 0.96 9.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 ORY19035.1 - 0.0033 16.7 0.0 2.8 7.0 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain Cytidylate_kin PF02224.18 ORY19035.1 - 0.0036 17.1 0.3 0.74 9.5 0.0 3.2 3 0 0 3 3 3 1 Cytidylate kinase PhoH PF02562.16 ORY19035.1 - 0.0057 16.1 0.0 0.36 10.2 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein ATPase_2 PF01637.18 ORY19035.1 - 0.0098 15.8 0.0 4.9 7.0 0.0 3.0 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea AAA_19 PF13245.6 ORY19035.1 - 0.011 16.0 1.8 4.3 7.7 0.3 3.1 2 1 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 ORY19035.1 - 0.02 14.8 0.1 6.4 6.6 0.0 3.0 2 1 0 2 2 2 0 NTPase ResIII PF04851.15 ORY19035.1 - 0.039 14.0 0.0 8.2 6.4 0.0 2.7 3 0 0 3 3 2 0 Type III restriction enzyme, res subunit Sigma54_activ_2 PF14532.6 ORY19035.1 - 0.041 14.0 0.0 3.2 7.9 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain AFG1_ATPase PF03969.16 ORY19035.1 - 0.055 12.4 0.0 4.4 6.1 0.0 2.4 2 0 0 2 2 2 0 AFG1-like ATPase CPT PF07931.12 ORY19035.1 - 0.065 13.1 0.1 2.4 8.0 0.0 2.7 3 0 0 3 3 2 0 Chloramphenicol phosphotransferase-like protein PduV-EutP PF10662.9 ORY19035.1 - 0.075 12.8 0.0 20 4.9 0.0 2.7 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation DUF2075 PF09848.9 ORY19035.1 - 0.12 11.6 0.0 11 5.1 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Parvo_NS1 PF01057.17 ORY19035.1 - 0.16 11.0 0.1 2.9 6.9 0.1 2.4 3 0 0 3 3 2 0 Parvovirus non-structural protein NS1 AAA_30 PF13604.6 ORY19035.1 - 0.16 11.7 1.6 25 4.5 0.0 3.2 4 0 0 4 4 3 0 AAA domain Snf7 PF03357.21 ORY19036.1 - 1.1e-31 109.8 10.0 1.1e-31 109.8 10.0 1.4 2 0 0 2 2 2 1 Snf7 IL34 PF15036.6 ORY19036.1 - 0.03 14.4 0.1 0.062 13.4 0.1 1.5 1 0 0 1 1 1 0 Interleukin 34 DUF4238 PF14022.6 ORY19036.1 - 0.43 10.1 2.4 0.56 9.7 1.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4238) Cob_adeno_trans PF01923.18 ORY19036.1 - 2.2 8.4 9.4 7.4 6.7 7.8 2.1 1 1 1 2 2 2 0 Cobalamin adenosyltransferase PITH PF06201.13 ORY19037.1 - 6.8e-43 146.5 0.0 8.3e-43 146.2 0.0 1.1 1 0 0 1 1 1 1 PITH domain LSM PF01423.22 ORY19038.1 - 5.7e-17 61.2 0.3 7.5e-17 60.8 0.3 1.1 1 0 0 1 1 1 1 LSM domain DUF3328 PF11807.8 ORY19040.1 - 4e-36 124.8 12.9 4.3e-35 121.5 12.9 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) Peptidase_M28 PF04389.17 ORY19041.1 - 7.3e-37 127.0 0.2 1.3e-36 126.2 0.1 1.4 2 0 0 2 2 2 1 Peptidase family M28 PA PF02225.22 ORY19041.1 - 7.8e-14 51.5 1.2 1.8e-13 50.3 1.2 1.6 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 ORY19041.1 - 8.7e-05 22.3 0.0 0.00016 21.4 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 LVIVD PF08309.11 ORY19042.1 - 0.009 15.3 0.3 0.053 12.8 0.1 2.4 2 0 0 2 2 2 1 LVIVD repeat AHSA1 PF08327.11 ORY19042.1 - 0.12 12.6 0.0 11 6.3 0.0 2.3 2 0 0 2 2 2 0 Activator of Hsp90 ATPase homolog 1-like protein HAD_2 PF13419.6 ORY19043.1 - 2.3e-22 79.9 0.0 3.1e-22 79.5 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ORY19043.1 - 1.2e-10 42.0 0.0 6.5e-10 39.7 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ORY19043.1 - 2.6e-05 24.2 0.0 4.6e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 ORY19043.1 - 0.017 15.5 0.0 0.024 15.0 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase DnaG_DnaB_bind PF08278.11 ORY19043.1 - 0.039 14.5 0.2 0.078 13.6 0.1 1.5 2 0 0 2 2 2 0 DNA primase DnaG DnaB-binding LPMO_10 PF03067.15 ORY19044.1 - 6.3e-11 43.3 0.3 1.2e-10 42.4 0.3 1.4 1 1 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading LRR_6 PF13516.6 ORY19045.1 - 3e-11 42.4 0.1 0.47 10.6 0.0 7.4 9 0 0 9 9 9 3 Leucine Rich repeat LRR_1 PF00560.33 ORY19045.1 - 0.001 19.3 0.7 7.9 7.5 0.0 5.2 4 0 0 4 4 4 1 Leucine Rich Repeat LRR_4 PF12799.7 ORY19045.1 - 0.0011 19.3 5.8 0.71 10.4 0.1 4.9 3 2 4 7 7 7 4 Leucine Rich repeats (2 copies) Aldedh PF00171.22 ORY19046.1 - 9.1e-150 499.2 0.4 1.1e-149 498.9 0.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 ORY19046.1 - 0.00015 20.9 0.0 0.00021 20.5 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.11 ORY19046.1 - 0.018 14.5 0.2 1 8.7 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) Abhydrolase_6 PF12697.7 ORY19047.1 - 3.6e-08 34.3 0.2 6.4e-08 33.5 0.2 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORY19047.1 - 1.7e-06 27.5 0.0 2.7e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ORY19047.1 - 0.00022 21.0 0.0 0.00048 19.9 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold FSH1 PF03959.13 ORY19047.1 - 0.087 12.5 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase (FSH1) FMN_dh PF01070.18 ORY19048.1 - 8.1e-114 380.3 0.0 9.7e-114 380.0 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 ORY19048.1 - 7.4e-21 74.1 0.0 1.5e-20 73.1 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 ORY19048.1 - 3e-05 23.3 0.1 5.7e-05 22.4 0.1 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 ORY19048.1 - 0.0046 16.0 0.0 0.036 13.1 0.0 2.1 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.14 ORY19048.1 - 0.042 13.2 0.0 0.69 9.2 0.0 2.2 1 1 1 2 2 2 0 Thiazole biosynthesis protein ThiG NMO PF03060.15 ORY19048.1 - 0.066 12.6 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase DHO_dh PF01180.21 ORY19048.1 - 0.22 10.7 0.0 0.44 9.7 0.0 1.4 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase Cation_ATPase_C PF00689.21 ORY19050.1 - 2.9e-39 134.7 11.1 2.9e-39 134.7 11.1 2.5 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 ORY19050.1 - 2.8e-34 118.2 0.2 2.8e-34 118.2 0.2 2.8 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 ORY19050.1 - 5.8e-18 64.8 0.0 1.1e-17 63.9 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 ORY19050.1 - 7.6e-18 65.6 0.0 1.4e-17 64.7 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 ORY19050.1 - 1.9e-07 30.6 0.0 6.4e-07 29.0 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 ORY19050.1 - 0.00061 19.6 0.2 0.0045 16.8 0.2 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Zn_clus PF00172.18 ORY19051.1 - 4.2e-09 36.4 14.1 6.5e-09 35.8 14.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RebB PF11747.8 ORY19051.1 - 0.18 11.9 0.2 0.52 10.4 0.2 1.7 1 0 0 1 1 1 0 Killing trait p450 PF00067.22 ORY19055.1 - 2.8e-36 125.3 0.1 2.3e-18 66.2 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 Synapsin_C PF02750.14 ORY19055.1 - 0.21 11.1 0.1 1.3 8.4 0.0 2.1 2 0 0 2 2 2 0 Synapsin, ATP binding domain 4HBT_3 PF13622.6 ORY19057.1 - 2.5e-26 93.4 2.4 7.6e-25 88.6 2.4 2.4 1 1 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 ORY19057.1 - 5.9e-09 35.9 0.8 0.094 12.6 0.0 4.1 3 1 1 4 4 4 4 Acyl-CoA thioesterase Amidase PF01425.21 ORY19058.1 - 2.6e-86 290.3 0.0 5.5e-86 289.3 0.0 1.5 1 1 0 1 1 1 1 Amidase MFS_1 PF07690.16 ORY19059.1 - 5e-11 42.1 8.0 5.7e-11 41.9 8.0 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.16 ORY19060.1 - 3.7e-18 65.6 9.0 4e-18 65.5 9.0 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Abhydrolase_6 PF12697.7 ORY19061.1 - 1.9e-14 54.8 0.0 2.3e-14 54.6 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORY19061.1 - 0.0064 15.8 0.0 0.041 13.1 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 ORY19061.1 - 0.041 13.6 0.0 0.068 12.9 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein LCAT PF02450.15 ORY19061.1 - 0.09 11.9 0.1 0.22 10.7 0.0 1.5 2 0 0 2 2 2 0 Lecithin:cholesterol acyltransferase Ser_hydrolase PF06821.13 ORY19061.1 - 0.17 11.7 0.0 9.8 6.0 0.0 2.2 2 0 0 2 2 2 0 Serine hydrolase p450 PF00067.22 ORY19062.1 - 7.7e-58 196.4 0.0 1e-57 195.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.25 ORY19063.1 - 1.4e-21 76.9 0.0 1.1e-19 70.7 0.0 2.0 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 ORY19063.1 - 4e-11 42.9 0.0 5.4e-11 42.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY19063.1 - 0.00093 19.2 0.0 0.0014 18.6 0.0 1.2 1 0 0 1 1 1 1 KR domain Enterotoxin_a PF01375.17 ORY19065.1 - 9.5e-08 31.9 0.0 1.6e-07 31.2 0.0 1.3 1 1 0 1 1 1 1 Heat-labile enterotoxin alpha chain Pertussis_S1 PF02917.14 ORY19065.1 - 0.01 15.7 0.0 0.02 14.7 0.0 1.6 2 0 0 2 2 2 1 Pertussis toxin, subunit 1 zf-met PF12874.7 ORY19067.1 - 5.9e-11 42.4 3.6 0.00013 22.2 0.9 2.4 2 1 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 ORY19067.1 - 1.5e-08 34.7 5.5 0.00069 19.8 1.7 2.4 2 1 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 ORY19067.1 - 3.8e-08 33.6 8.1 0.00079 19.7 0.1 2.0 1 1 1 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 ORY19067.1 - 7.1e-08 32.3 10.0 0.0013 18.7 0.0 3.0 2 1 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 ORY19067.1 - 2.7e-07 30.7 11.0 0.0014 18.9 0.2 2.6 2 1 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY19067.1 - 0.00029 21.4 12.5 0.15 13.0 0.1 3.1 2 1 0 2 2 2 1 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 ORY19067.1 - 0.0003 20.8 3.1 0.13 12.4 0.3 2.1 2 0 0 2 2 2 2 Zinc ribbon domain zf-C2H2_8 PF15909.5 ORY19067.1 - 0.00038 20.7 2.3 0.095 13.0 0.5 2.1 1 1 1 2 2 2 2 C2H2-type zinc ribbon zf-H2C2_2 PF13465.6 ORY19067.1 - 0.00094 19.5 2.8 0.089 13.3 0.1 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf_UBZ PF18439.1 ORY19067.1 - 0.0019 17.7 5.6 0.12 11.9 0.9 2.2 2 0 0 2 2 2 2 Ubiquitin-Binding Zinc Finger zinc-ribbons_6 PF07191.12 ORY19067.1 - 0.011 15.6 4.9 0.38 10.8 5.0 2.1 1 1 0 1 1 1 0 zinc-ribbons Cas_CXXC_CXXC PF09706.10 ORY19067.1 - 0.019 15.2 0.4 3.1 8.1 0.1 2.1 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_CXXC_CXXC) zf-DNA_Pol PF08996.10 ORY19067.1 - 0.031 14.0 0.7 0.038 13.8 0.7 1.0 1 0 0 1 1 1 0 DNA Polymerase alpha zinc finger DUF2197 PF09963.9 ORY19067.1 - 0.07 13.4 1.5 5.4 7.4 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) C1_4 PF07975.12 ORY19067.1 - 0.077 13.2 3.8 0.34 11.2 3.5 2.0 1 1 1 2 2 2 0 TFIIH C1-like domain LIM PF00412.22 ORY19067.1 - 0.081 13.2 4.9 0.12 12.7 4.9 1.4 1 0 0 1 1 1 0 LIM domain zf-DBF PF07535.12 ORY19067.1 - 0.18 11.9 6.2 3.5 7.8 1.4 2.4 2 1 0 2 2 2 0 DBF zinc finger DUF983 PF06170.12 ORY19067.1 - 0.21 12.0 2.1 8.7 6.8 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF983) Vps39_2 PF10367.9 ORY19067.1 - 0.21 12.0 3.0 8.7 6.8 0.4 2.1 1 1 1 2 2 2 0 Vacuolar sorting protein 39 domain 2 Rep_fac-A_C PF08646.10 ORY19067.1 - 1 9.1 5.8 10 5.8 5.8 2.0 1 1 0 1 1 1 0 Replication factor-A C terminal domain zinc_ribbon_5 PF13719.6 ORY19067.1 - 1.1 9.1 5.5 9.9 6.0 0.3 2.1 2 0 0 2 2 2 0 zinc-ribbon domain Actin_micro PF17003.5 ORY19067.1 - 8.2 5.5 6.8 6.2 5.9 2.4 1.9 1 1 1 2 2 2 0 Putative actin-like family Ntox15 PF15604.6 ORY19068.1 - 0.68 10.0 11.1 0.75 9.9 9.9 1.6 1 1 0 1 1 1 0 Novel toxin 15 Presenilin PF01080.17 ORY19068.1 - 2.1 7.0 5.2 2.5 6.8 5.2 1.1 1 0 0 1 1 1 0 Presenilin NAP PF00956.18 ORY19068.1 - 2.3 7.3 5.5 3.1 6.9 5.5 1.1 1 0 0 1 1 1 0 Nucleosome assembly protein (NAP) DUF4554 PF15091.6 ORY19068.1 - 6.1 5.6 9.8 7.6 5.3 9.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) RR_TM4-6 PF06459.12 ORY19068.1 - 7.4 6.3 9.6 10 5.8 9.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TPR_10 PF13374.6 ORY19069.1 - 4.7e-38 128.0 2.9 1.8e-12 46.7 0.1 3.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 ORY19069.1 - 1.2e-37 128.0 7.7 4.4e-20 71.7 0.7 3.0 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.6 ORY19069.1 - 2.9e-16 58.2 5.8 3.6e-05 23.5 0.2 3.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 ORY19069.1 - 2.5e-13 49.2 5.8 0.00044 20.0 0.1 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 ORY19069.1 - 6.1e-09 36.4 5.1 0.0002 21.9 1.9 2.9 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 ORY19069.1 - 8.4e-09 34.9 6.6 0.031 14.4 0.1 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_4 PF07721.14 ORY19069.1 - 1.9e-07 31.0 0.1 0.017 15.7 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 ORY19069.1 - 3.2e-07 30.6 1.2 0.22 12.4 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_MalT PF17874.1 ORY19069.1 - 2.7e-06 27.0 0.5 1.6e-05 24.5 0.4 1.8 1 1 0 1 1 1 1 MalT-like TPR region TPR_8 PF13181.6 ORY19069.1 - 2.7e-05 24.0 0.9 1.2 9.5 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY19069.1 - 4.3e-05 23.6 0.2 0.015 15.5 0.0 2.4 1 1 2 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 ORY19069.1 - 0.0014 17.9 0.4 0.097 11.9 0.2 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 ORY19069.1 - 0.0025 18.3 1.0 0.14 12.6 0.7 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 ORY19069.1 - 0.0027 17.4 1.4 2.2 8.0 0.0 3.0 3 0 0 3 3 3 2 TPR repeat TPR_17 PF13431.6 ORY19069.1 - 0.0051 17.1 2.2 2 9.0 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_3 PF07720.12 ORY19069.1 - 0.01 15.8 0.0 5.6 7.1 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_5 PF12688.7 ORY19069.1 - 0.016 15.5 1.6 0.19 12.0 1.4 2.1 1 1 0 1 1 1 0 Tetratrico peptide repeat Ribosomal_S7 PF00177.21 ORY19069.1 - 0.027 14.1 0.0 1.7 8.2 0.0 2.1 1 1 1 2 2 2 0 Ribosomal protein S7p/S5e Coatomer_E PF04733.14 ORY19069.1 - 0.048 13.1 0.1 0.13 11.7 0.1 1.6 1 1 1 2 2 2 0 Coatomer epsilon subunit Rep_3 PF01051.21 ORY19069.1 - 0.06 13.1 0.0 1.7 8.4 0.0 2.0 1 1 0 1 1 1 0 Initiator Replication protein Cys_box PF17869.1 ORY19069.1 - 0.1 12.7 0.1 9.2 6.5 0.0 2.5 3 0 0 3 3 3 0 Anosmin cysteine rich domain DUF4145 PF13643.6 ORY19069.1 - 0.12 12.6 0.2 65 3.8 0.0 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4145) Wzy_C_2 PF11846.8 ORY19069.1 - 0.31 10.9 0.5 6.3 6.7 0.1 2.5 2 1 1 3 3 3 0 Virulence factor membrane-bound polymerase, C-terminal TPR_12 PF13424.6 ORY19070.1 - 5.7e-18 65.0 0.8 1.1e-09 38.4 0.1 2.0 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 ORY19070.1 - 1.5e-11 43.8 0.0 2.9e-06 27.0 0.0 2.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_3 PF07720.12 ORY19070.1 - 0.0043 17.0 0.2 0.0099 15.9 0.2 1.6 1 1 0 1 1 1 1 Tetratricopeptide repeat Tnp_22_trimer PF17489.2 ORY19070.1 - 0.011 15.7 0.1 0.021 14.8 0.1 1.4 1 0 0 1 1 1 0 L1 transposable element trimerization domain MIT PF04212.18 ORY19070.1 - 0.023 14.8 0.1 0.03 14.4 0.1 1.3 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain TPR_1 PF00515.28 ORY19070.1 - 0.058 13.2 0.1 0.13 12.2 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat iPGM_N PF06415.13 ORY19070.1 - 0.16 11.4 0.0 0.16 11.4 0.0 1.1 1 0 0 1 1 1 0 BPG-independent PGAM N-terminus (iPGM_N) HTH_38 PF13936.6 ORY19071.1 - 2.8e-05 23.8 0.8 2.8e-05 23.8 0.8 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 ORY19071.1 - 0.016 14.8 0.1 0.03 14.0 0.1 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 NACHT PF05729.12 ORY19072.1 - 4.4e-07 30.0 0.4 8.2e-07 29.1 0.4 1.4 1 0 0 1 1 1 1 NACHT domain HET PF06985.11 ORY19072.1 - 0.084 13.2 0.0 0.58 10.5 0.1 2.2 1 1 0 1 1 1 0 Heterokaryon incompatibility protein (HET) DUF2730 PF10805.8 ORY19074.1 - 0.00078 19.5 5.8 1.2 9.3 1.0 3.4 1 1 1 2 2 2 2 Protein of unknown function (DUF2730) DUF3106 PF11304.8 ORY19074.1 - 0.0084 16.6 10.7 0.031 14.7 10.7 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF3106) CD34_antigen PF06365.12 ORY19074.1 - 0.024 14.2 13.3 13 5.3 0.1 4.8 1 1 4 5 5 5 0 CD34/Podocalyxin family DUF3723 PF12520.8 ORY19075.1 - 8.2e-13 47.9 0.1 8.6e-13 47.8 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3723) Collagen PF01391.18 ORY19076.1 - 0.058 13.2 2.1 0.098 12.4 2.1 1.3 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) Macoilin PF09726.9 ORY19076.1 - 4.5 5.7 7.6 5 5.6 7.6 1.0 1 0 0 1 1 1 0 Macoilin family Glyco_tranf_2_3 PF13641.6 ORY19078.1 - 1.5e-09 38.1 0.0 1.9e-09 37.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 ORY19078.1 - 0.0001 21.8 0.0 0.00027 20.5 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 ORY19078.1 - 0.0031 17.3 0.0 0.0055 16.5 0.0 1.4 1 1 0 1 1 1 1 Glycosyl transferase family 2 TPR_10 PF13374.6 ORY19079.1 - 6.9e-21 73.4 1.2 1e-09 37.9 0.1 3.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 ORY19079.1 - 8.1e-17 61.3 3.8 4.9e-15 55.6 0.2 2.2 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 ORY19079.1 - 0.00017 21.4 3.7 0.13 12.4 0.0 3.1 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 ORY19079.1 - 0.11 12.7 1.1 33 4.9 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat RasGEF_N PF00618.20 ORY19080.1 - 0.051 13.8 1.3 0.078 13.2 1.2 1.4 1 1 0 1 1 1 0 RasGEF N-terminal motif PAM2 PF07145.15 ORY19115.1 - 0.0032 17.1 0.0 0.0072 15.9 0.0 1.6 1 0 0 1 1 1 1 Ataxin-2 C-terminal region Asp PF00026.23 ORY19117.1 - 1.4e-09 37.8 2.6 2.5e-09 37.0 2.6 1.4 1 1 0 1 1 1 1 Eukaryotic aspartyl protease BppU_N PF10651.9 ORY19117.1 - 0.0036 17.0 0.2 0.0062 16.2 0.2 1.4 1 0 0 1 1 1 1 BppU N-terminal domain CAF1A PF12253.8 ORY19118.1 - 3.2e-22 78.5 8.4 3.2e-22 78.5 8.4 3.4 2 1 0 2 2 1 1 Chromatin assembly factor 1 subunit A MDM1 PF15501.6 ORY19118.1 - 0.046 12.9 29.8 0.087 12.0 29.8 1.4 1 0 0 1 1 1 0 Nuclear protein MDM1 SprA-related PF12118.8 ORY19118.1 - 0.055 12.6 17.4 0.092 11.9 17.4 1.3 1 0 0 1 1 1 0 SprA-related family LAP1C PF05609.12 ORY19118.1 - 0.15 11.2 16.2 0.21 10.6 16.2 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) CAF-1_p150 PF11600.8 ORY19118.1 - 0.45 10.2 48.8 0.85 9.3 48.8 1.4 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Raftlin PF15250.6 ORY19118.1 - 0.74 8.5 14.2 1.2 7.9 14.2 1.2 1 0 0 1 1 1 0 Raftlin Hamartin PF04388.12 ORY19118.1 - 1.6 7.3 22.6 2.5 6.7 22.6 1.3 1 0 0 1 1 1 0 Hamartin protein DUF262 PF03235.14 ORY19118.1 - 2.6 8.2 9.0 5.6 7.1 9.0 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF262 Asp-B-Hydro_N PF05279.11 ORY19118.1 - 2.9 7.9 26.1 6.1 6.8 26.1 1.5 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Cwf_Cwc_15 PF04889.12 ORY19118.1 - 3.1 7.5 39.3 1.2 8.8 26.7 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein DUF5427 PF10310.9 ORY19118.1 - 3.2 6.6 23.9 4.9 6.0 23.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5427) DDRGK PF09756.9 ORY19118.1 - 5.1 6.7 38.5 13 5.3 38.5 1.7 1 0 0 1 1 1 0 DDRGK domain TP6A_N PF04406.14 ORY19119.1 - 3.2e-21 75.1 0.3 1.6e-20 72.8 0.1 2.3 2 0 0 2 2 2 1 Type IIB DNA topoisomerase DUF2399 PF09664.10 ORY19119.1 - 0.061 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2399) MFS_1 PF07690.16 ORY19123.1 - 1.5e-13 50.4 4.8 1.5e-13 50.4 4.8 3.3 3 1 0 3 3 3 2 Major Facilitator Superfamily DUF2157 PF09925.9 ORY19123.1 - 0.089 12.6 7.0 0.96 9.2 5.0 3.3 2 1 0 2 2 2 0 Predicted membrane protein (DUF2157) Ig_GlcNase PF18368.1 ORY19124.1 - 1e-33 115.6 0.2 4.4e-33 113.6 0.1 2.2 2 0 0 2 2 2 1 Exo-beta-D-glucosaminidase Ig-fold domain Mannosidase_ig PF17786.1 ORY19124.1 - 2.9e-08 34.2 0.3 4.8e-07 30.3 0.0 2.8 3 0 0 3 3 3 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 ORY19124.1 - 2e-06 28.4 0.1 0.00012 22.7 0.0 3.2 4 0 0 4 4 4 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.18 ORY19124.1 - 4.3e-06 26.7 0.1 1.1e-05 25.4 0.1 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Ig_mannosidase PF17753.1 ORY19124.1 - 0.00015 21.5 0.0 0.00045 19.9 0.0 1.8 1 0 0 1 1 1 1 Ig-fold domain BetaGal_dom4_5 PF13364.6 ORY19124.1 - 0.05 14.2 0.5 0.23 12.1 0.5 2.2 1 0 0 1 1 1 0 Beta-galactosidase jelly roll domain TPR_2 PF07719.17 ORY19125.1 - 9.3e-29 97.2 6.2 0.00014 21.7 0.0 11.4 12 0 0 12 12 12 6 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY19125.1 - 1.5e-27 95.6 7.3 1.1e-24 86.5 0.4 4.9 4 2 2 6 6 6 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 ORY19125.1 - 7.4e-26 88.9 0.0 4.8e-06 26.2 0.1 10.6 11 0 0 11 11 11 6 Tetratricopeptide repeat TPR_19 PF14559.6 ORY19125.1 - 8.4e-23 80.7 4.2 0.0029 18.1 0.0 7.7 5 2 3 8 8 8 5 Tetratricopeptide repeat TPR_8 PF13181.6 ORY19125.1 - 7.4e-22 75.7 0.0 0.00051 20.0 0.1 9.1 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_12 PF13424.6 ORY19125.1 - 2.1e-20 72.8 12.2 1.2e-07 31.9 0.1 9.1 9 1 0 9 9 9 4 Tetratricopeptide repeat TPR_16 PF13432.6 ORY19125.1 - 2.1e-14 53.9 13.3 0.0018 18.9 0.2 8.6 6 3 3 9 9 9 4 Tetratricopeptide repeat TPR_14 PF13428.6 ORY19125.1 - 3.4e-14 52.3 14.9 0.028 15.2 0.0 10.2 6 2 5 11 11 11 2 Tetratricopeptide repeat TPR_11 PF13414.6 ORY19125.1 - 4.6e-11 42.2 3.9 0.44 10.3 0.0 7.5 8 1 1 9 9 9 3 TPR repeat TPR_6 PF13174.6 ORY19125.1 - 5.5e-08 32.9 2.9 1.3 9.8 0.1 6.8 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 ORY19125.1 - 2.2e-06 27.7 0.0 75 4.0 0.0 7.8 7 1 1 8 8 8 0 Tetratricopeptide repeat TPR_4 PF07721.14 ORY19125.1 - 4.3e-06 26.8 3.8 0.12 13.0 0.1 6.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_15 PF13429.6 ORY19125.1 - 2.2e-05 23.8 1.0 0.39 9.9 0.0 4.1 3 2 0 3 3 3 1 Tetratricopeptide repeat TPR_MalT PF17874.1 ORY19125.1 - 2.5e-05 23.8 5.2 0.079 12.3 0.0 5.0 4 1 2 6 6 6 1 MalT-like TPR region TPR_10 PF13374.6 ORY19125.1 - 2.6e-05 24.0 9.3 0.21 11.5 0.0 7.1 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_7 PF13176.6 ORY19125.1 - 3.8e-05 23.4 15.9 0.59 10.3 0.0 8.1 11 0 0 11 11 9 1 Tetratricopeptide repeat TPR_9 PF13371.6 ORY19125.1 - 4.2e-05 23.6 9.9 0.31 11.2 0.5 5.7 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_5 PF12688.7 ORY19125.1 - 0.0013 18.9 0.8 0.0049 17.1 0.1 2.4 3 0 0 3 3 1 1 Tetratrico peptide repeat TPR_21 PF09976.9 ORY19125.1 - 0.0022 17.7 0.4 3.9 7.1 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat-like domain PPR PF01535.20 ORY19125.1 - 0.061 13.6 0.0 42 4.7 0.0 4.0 3 0 0 3 3 3 0 PPR repeat SRP_TPR_like PF17004.5 ORY19125.1 - 0.086 12.9 0.0 6.7 6.8 0.0 3.3 3 1 1 4 4 4 0 Putative TPR-like repeat Fis1_TPR_C PF14853.6 ORY19125.1 - 0.16 12.1 6.2 4.2 7.5 0.1 4.6 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat TEX29 PF15839.5 ORY19125.1 - 1 10.0 2.4 16 6.2 0.3 2.3 1 1 1 2 2 2 0 Testis-expressed sequence 29 protein DUF572 PF04502.13 ORY19126.1 - 2.1e-72 244.5 11.8 2.5e-72 244.3 11.8 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) zf-ACC PF17848.1 ORY19126.1 - 0.047 13.8 2.4 0.23 11.6 0.3 2.3 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain zf-FCS PF06467.14 ORY19126.1 - 0.69 9.9 3.1 3.4 7.7 0.2 2.3 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif Glyco_hydro_32N PF00251.20 ORY19127.1 - 0.0036 16.9 0.0 0.01 15.4 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Saf_2TM PF18303.1 ORY19128.1 - 0.091 12.3 0.0 0.3 10.7 0.1 1.7 2 0 0 2 2 2 0 SAVED-fused 2TM effector domain Glyco_hydro_92 PF07971.12 ORY19129.1 - 1.9e-145 485.3 0.0 2.3e-145 485.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 ORY19129.1 - 7.5e-66 222.4 0.4 1.2e-65 221.7 0.4 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain Ku_C PF03730.14 ORY19130.1 - 0.2 12.4 1.3 21 5.9 0.3 2.2 2 0 0 2 2 2 0 Ku70/Ku80 C-terminal arm SARAF PF06682.12 ORY19132.1 - 4.1e-06 26.7 0.4 4.5e-06 26.5 0.4 1.0 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis EphA2_TM PF14575.6 ORY19132.1 - 5.7e-05 23.9 0.0 0.00013 22.7 0.0 1.6 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Shisa PF13908.6 ORY19132.1 - 0.00036 20.8 0.2 0.00041 20.7 0.2 1.1 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Herpes_gE PF02480.16 ORY19132.1 - 0.00046 19.1 0.1 0.00051 18.9 0.1 1.1 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E Pro-rich PF15240.6 ORY19132.1 - 0.0005 20.4 12.9 0.0007 19.9 12.9 1.2 1 0 0 1 1 1 1 Proline-rich GRP PF07172.11 ORY19132.1 - 0.0011 19.6 1.7 0.0013 19.3 1.1 1.5 1 1 0 1 1 1 1 Glycine rich protein family RIFIN PF02009.16 ORY19132.1 - 0.0022 18.0 3.6 0.0028 17.6 3.6 1.1 1 0 0 1 1 1 1 Rifin DUF5385 PF17359.2 ORY19132.1 - 0.0035 16.9 5.5 0.0035 16.9 5.5 1.5 1 1 0 1 1 1 1 Family of unknown function (DUF5385) Adeno_E3_CR2 PF02439.15 ORY19132.1 - 0.0038 17.0 7.8 0.0067 16.2 7.8 1.3 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 DUF2207 PF09972.9 ORY19132.1 - 0.0038 16.1 0.0 0.0038 16.1 0.0 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) CYYR1 PF10873.8 ORY19132.1 - 0.0038 17.7 0.4 0.005 17.3 0.4 1.1 1 0 0 1 1 1 1 Cysteine and tyrosine-rich protein 1 Mid2 PF04478.12 ORY19132.1 - 0.0042 16.9 0.5 0.0055 16.5 0.5 1.1 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor MscL PF01741.18 ORY19132.1 - 0.0082 16.4 0.2 0.01 16.2 0.2 1.1 1 0 0 1 1 1 1 Large-conductance mechanosensitive channel, MscL T4SS_CagC PF16943.5 ORY19132.1 - 0.012 15.8 0.9 0.014 15.5 0.9 1.2 1 0 0 1 1 1 0 Cag pathogenicity island, type IV secretory system Amnionless PF14828.6 ORY19132.1 - 0.013 14.4 0.1 0.014 14.3 0.1 1.1 1 0 0 1 1 1 0 Amnionless TMEM51 PF15345.6 ORY19132.1 - 0.018 14.9 0.1 0.022 14.6 0.1 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 Stevor PF17410.2 ORY19132.1 - 0.018 14.6 0.5 0.023 14.3 0.5 1.1 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame Protocadherin PF08374.11 ORY19132.1 - 0.018 15.0 0.4 0.02 14.9 0.4 1.1 1 0 0 1 1 1 0 Protocadherin Orf78 PF06024.12 ORY19132.1 - 0.02 15.2 0.2 0.027 14.8 0.2 1.2 1 0 0 1 1 1 0 Orf78 (ac78) Baculo_11_kDa PF06143.11 ORY19132.1 - 0.034 13.7 3.7 0.055 13.1 3.7 1.3 1 0 0 1 1 1 0 Baculovirus 11 kDa family Glucos_trans_II PF14264.6 ORY19132.1 - 0.037 13.4 0.2 0.041 13.2 0.2 1.1 1 0 0 1 1 1 0 Glucosyl transferase GtrII YajC PF02699.15 ORY19132.1 - 0.038 13.9 2.7 0.038 13.9 2.7 1.7 2 0 0 2 2 2 0 Preprotein translocase subunit VSP PF03302.13 ORY19132.1 - 0.039 12.8 0.2 0.049 12.5 0.2 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein DUF5305 PF17231.2 ORY19132.1 - 0.049 13.0 0.2 0.062 12.7 0.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5305) ECSCR PF15820.5 ORY19132.1 - 0.068 13.0 0.6 0.096 12.5 0.6 1.3 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator RIC3 PF15361.6 ORY19132.1 - 0.076 13.4 0.8 0.099 13.0 0.5 1.3 1 1 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 O-antigen_lig PF13425.6 ORY19132.1 - 0.083 11.7 3.5 0.11 11.2 3.5 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Pox_EPC_I2-L1 PF12575.8 ORY19132.1 - 0.084 13.1 0.2 0.13 12.5 0.2 1.2 1 0 0 1 1 1 0 Poxvirus entry protein complex L1 and I2 ABC2_membrane_3 PF12698.7 ORY19132.1 - 0.085 11.9 0.1 0.099 11.7 0.1 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF3413 PF11893.8 ORY19132.1 - 0.11 11.7 0.4 0.13 11.4 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3413) TMEM154 PF15102.6 ORY19132.1 - 0.13 12.2 6.9 0.17 11.8 6.9 1.3 1 1 0 1 1 1 0 TMEM154 protein family Rax2 PF12768.7 ORY19132.1 - 0.13 11.7 0.4 0.16 11.4 0.4 1.1 1 0 0 1 1 1 0 Cortical protein marker for cell polarity RCR PF12273.8 ORY19132.1 - 0.14 12.8 14.1 0.37 11.4 14.1 1.7 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red DUF4690 PF15756.5 ORY19132.1 - 0.14 12.8 0.4 0.21 12.2 0.4 1.3 1 0 0 1 1 1 0 Small Novel Rich in Cartilage Podoplanin PF05808.11 ORY19132.1 - 0.16 12.1 0.7 0.19 11.8 0.7 1.2 1 0 0 1 1 1 0 Podoplanin EzrA PF06160.12 ORY19132.1 - 0.16 10.1 0.7 0.18 10.0 0.7 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Glycophorin_A PF01102.18 ORY19132.1 - 0.18 12.0 0.9 0.25 11.6 0.9 1.3 1 0 0 1 1 1 0 Glycophorin A DUF2434 PF10361.9 ORY19132.1 - 0.21 10.6 0.4 0.25 10.3 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2434) SIT PF15330.6 ORY19132.1 - 0.21 12.0 1.6 0.4 11.2 1.6 1.6 1 1 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT DUF4834 PF16118.5 ORY19132.1 - 0.21 12.6 3.3 0.19 12.7 2.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) Syndecan PF01034.20 ORY19132.1 - 0.47 10.4 4.1 0.88 9.5 4.1 1.5 1 0 0 1 1 1 0 Syndecan domain Insulin_TMD PF17870.1 ORY19132.1 - 1.5 9.0 11.7 3 8.0 11.7 1.5 1 1 0 1 1 1 0 Insulin receptor trans-membrane segment FeoB_associated PF12669.7 ORY19132.1 - 2.4 8.6 11.6 0.71 10.3 6.0 2.2 2 0 0 2 2 2 0 FeoB-associated Cys-rich membrane protein ASFV_J13L PF05568.11 ORY19132.1 - 3.3 7.4 8.6 2.1 8.1 6.8 1.6 1 1 1 2 2 2 0 African swine fever virus J13L protein Vpu PF00558.19 ORY19132.1 - 5.9 6.7 9.3 5.1 7.0 8.3 1.4 1 1 0 1 1 1 0 Vpu protein Vps54 PF07928.12 ORY19133.1 - 1.2e-48 165.0 0.5 3.9e-48 163.3 0.5 2.0 1 0 0 1 1 1 1 Vps54-like protein Vps54_N PF10475.9 ORY19133.1 - 2.2e-05 23.9 0.1 2.2e-05 23.9 0.1 2.3 3 0 0 3 3 3 1 Vacuolar-sorting protein 54, of GARP complex Pox_A22 PF04848.13 ORY19133.1 - 0.12 12.5 0.2 0.25 11.4 0.2 1.5 1 0 0 1 1 1 0 Poxvirus A22 protein IDO PF01231.18 ORY19134.1 - 0.051 12.3 0.4 0.52 9.0 0.2 2.2 1 1 0 2 2 2 0 Indoleamine 2,3-dioxygenase zf-RING_2 PF13639.6 ORY19138.1 - 1.3e-07 31.9 6.0 1.3e-07 31.9 6.0 2.6 3 0 0 3 3 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 ORY19138.1 - 0.00046 20.0 7.4 0.00048 19.9 3.7 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORY19138.1 - 0.00051 20.0 1.0 0.00051 20.0 1.0 2.3 2 1 1 3 3 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 ORY19138.1 - 0.0021 17.9 5.0 0.0021 17.9 5.0 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 ORY19138.1 - 0.0024 17.7 0.9 0.0024 17.7 0.9 3.0 2 1 1 3 3 3 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 ORY19138.1 - 0.0028 17.6 5.4 0.0028 17.6 5.4 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 ORY19138.1 - 0.013 15.7 3.8 0.013 15.7 3.8 2.0 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 ORY19138.1 - 0.013 15.5 4.5 0.12 12.4 3.4 2.8 3 1 0 3 3 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 ORY19138.1 - 0.019 15.3 2.5 0.019 15.3 2.5 3.6 3 1 0 4 4 4 0 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 ORY19138.1 - 0.031 14.1 4.9 0.031 14.1 4.9 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Rad50_zn_hook PF04423.14 ORY19138.1 - 0.29 11.0 5.8 2 8.3 0.9 3.4 4 0 0 4 4 4 0 Rad50 zinc hook motif CTU2 PF10288.9 ORY19138.1 - 0.34 11.2 2.3 11 6.3 0.0 2.7 2 1 0 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 RINGv PF12906.7 ORY19138.1 - 0.93 9.7 8.9 0.65 10.2 1.4 3.4 3 0 0 3 3 3 0 RING-variant domain vATP-synt_E PF01991.18 ORY19140.1 - 0.0023 17.3 0.1 0.003 17.0 0.1 1.2 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit GIT_CC PF16559.5 ORY19140.1 - 0.024 14.5 1.6 0.66 9.9 0.2 2.4 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor ZapB PF06005.12 ORY19140.1 - 0.1 13.1 2.3 0.3 11.6 0.4 2.1 2 0 0 2 2 2 0 Cell division protein ZapB DEAD PF00270.29 ORY19141.1 - 3e-41 141.1 0.1 5.5e-41 140.2 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY19141.1 - 3.1e-33 114.4 0.0 1e-32 112.7 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 ORY19141.1 - 0.00057 19.6 0.1 0.00086 19.1 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 ORY19141.1 - 0.00087 19.6 0.1 0.0064 16.8 0.1 2.1 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 ORY19141.1 - 0.0011 19.0 0.0 0.0022 18.0 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.14 ORY19141.1 - 0.005 16.7 0.0 0.0082 16.0 0.0 1.4 1 0 0 1 1 1 1 Helicase TniB PF05621.11 ORY19141.1 - 0.035 13.5 0.0 0.082 12.3 0.0 1.6 1 0 0 1 1 1 0 Bacterial TniB protein UTP25 PF06862.12 ORY19141.1 - 0.064 12.0 0.0 6.6 5.4 0.0 2.1 2 0 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Flavi_DEAD PF07652.14 ORY19141.1 - 0.068 13.1 0.7 0.21 11.6 0.1 2.2 2 1 0 2 2 2 0 Flavivirus DEAD domain AAA_22 PF13401.6 ORY19141.1 - 0.25 11.6 0.8 1.1 9.5 0.8 2.0 1 1 0 1 1 1 0 AAA domain DUF3449 PF11931.8 ORY19142.1 - 5.6e-78 261.0 0.1 1.2e-77 259.9 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3449) SF3A3 PF16837.5 ORY19142.1 - 4e-26 91.3 0.5 1.2e-25 89.9 0.5 1.8 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 zf-met PF12874.7 ORY19142.1 - 1.2e-08 35.1 0.4 1.8e-06 28.1 0.1 2.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 ORY19142.1 - 2e-07 31.1 0.0 2e-07 31.1 0.0 2.7 2 1 0 2 2 2 1 Zinc-finger double-stranded RNA-binding SF3a60_bindingd PF12108.8 ORY19142.1 - 3.1e-07 30.2 0.0 8.7e-07 28.7 0.0 1.8 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-C2H2_2 PF12756.7 ORY19142.1 - 0.011 16.0 0.0 0.14 12.5 0.0 2.5 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) PRP9_N PF16958.5 ORY19142.1 - 0.017 15.1 3.0 0.017 15.1 3.0 3.8 4 2 1 5 5 5 0 Pre-mRNA-splicing factor PRP9 N-terminus PHO4 PF01384.20 ORY19143.1 - 2.1e-117 391.9 18.2 2.5e-117 391.7 18.2 1.0 1 0 0 1 1 1 1 Phosphate transporter family DUF4212 PF13937.6 ORY19143.1 - 0.19 12.1 0.3 0.19 12.1 0.3 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF4212) MCM PF00493.23 ORY19145.1 - 4e-104 346.6 0.1 1.8e-103 344.4 0.0 1.9 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 ORY19145.1 - 4.2e-36 123.6 0.1 8e-36 122.7 0.1 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 ORY19145.1 - 6.6e-29 100.2 1.3 1.5e-28 99.0 1.3 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 ORY19145.1 - 8e-15 55.3 0.2 2e-14 54.1 0.2 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 ORY19145.1 - 4.4e-06 26.2 0.0 0.00075 18.9 0.0 2.4 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 ORY19145.1 - 3.8e-05 23.7 0.0 0.00011 22.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 ORY19145.1 - 0.00048 20.0 0.0 0.0019 18.1 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 ORY19145.1 - 0.044 13.5 0.0 1.5 8.5 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain Mg_chelatase_C PF13335.6 ORY19145.1 - 0.12 13.0 2.3 0.21 12.2 0.3 2.4 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI C-terminal UDPGT PF00201.18 ORY19146.1 - 1.1e-05 24.4 0.0 1.6e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 ORY19146.1 - 0.042 13.8 0.0 0.086 12.8 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain AAA_22 PF13401.6 ORY19148.1 - 0.015 15.6 0.1 2.5 8.4 0.0 2.7 3 0 0 3 3 3 0 AAA domain DUF853 PF05872.12 ORY19148.1 - 0.11 11.1 0.0 0.17 10.5 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) CFEM PF05730.11 ORY19149.1 - 6.6e-06 26.1 19.0 1.1e-05 25.4 19.0 1.4 1 0 0 1 1 1 1 CFEM domain DUF4492 PF14899.6 ORY19150.1 - 0.33 10.9 1.5 0.74 9.8 1.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4492) Atg14 PF10186.9 ORY19151.1 - 0.0035 16.5 7.5 0.0035 16.5 7.5 1.8 2 0 0 2 2 2 1 Vacuolar sorting 38 and autophagy-related subunit 14 Leu_zip PF15294.6 ORY19151.1 - 0.012 15.2 7.8 0.027 14.0 7.8 1.5 1 0 0 1 1 1 0 Leucine zipper DUF2203 PF09969.9 ORY19151.1 - 0.2 12.4 5.9 0.076 13.7 1.9 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) CENP-F_leu_zip PF10473.9 ORY19151.1 - 1 9.4 22.5 0.045 13.8 4.5 3.2 3 1 1 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.6 ORY19151.1 - 1.1 8.6 16.4 0.32 10.3 11.0 2.5 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF724 PF05266.14 ORY19151.1 - 4.8 7.0 11.3 0.23 11.2 4.7 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF724) TPR_MLP1_2 PF07926.12 ORY19151.1 - 5 7.2 22.2 0.078 13.0 7.6 3.4 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein APG6_N PF17675.1 ORY19151.1 - 6.2 7.4 21.5 14 6.2 13.5 3.5 3 1 0 3 3 3 0 Apg6 coiled-coil region ABC_tran_CTD PF16326.5 ORY19151.1 - 6.5 7.1 11.4 8.9 6.6 1.5 3.6 3 0 0 3 3 3 0 ABC transporter C-terminal domain HSP70 PF00012.20 ORY19152.1 - 8.2e-05 21.0 0.0 0.0029 15.9 0.0 2.2 2 0 0 2 2 2 2 Hsp70 protein Peptidase_M22 PF00814.25 ORY19152.1 - 0.17 11.5 0.0 0.32 10.6 0.0 1.5 1 1 0 1 1 1 0 Glycoprotease family TauD PF02668.16 ORY19153.1 - 5.9e-54 183.7 0.9 7e-54 183.4 0.9 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family PXT1 PF15214.6 ORY19153.1 - 0.093 13.1 0.1 0.29 11.5 0.1 1.8 1 0 0 1 1 1 0 Peroxisomal testis-specific protein 1 EGF_3 PF12947.7 ORY19154.1 - 0.012 15.8 4.4 0.033 14.4 4.4 1.8 1 0 0 1 1 1 0 EGF domain ParA PF10609.9 ORY19155.1 - 2.3e-87 292.5 0.1 1.5e-85 286.6 0.1 2.0 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 ORY19155.1 - 9.9e-12 45.0 0.0 5.2e-11 42.7 0.0 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.11 ORY19155.1 - 7.8e-08 31.9 0.0 4.5e-06 26.2 0.0 2.1 1 1 0 2 2 2 1 ATPase MipZ ArsA_ATPase PF02374.15 ORY19155.1 - 1.2e-06 27.9 0.3 6.1e-05 22.4 0.2 2.2 2 0 0 2 2 2 1 Anion-transporting ATPase AAA_31 PF13614.6 ORY19155.1 - 5e-05 23.3 0.0 0.00096 19.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_26 PF13500.6 ORY19155.1 - 0.00031 20.6 0.6 0.027 14.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain MeaB PF03308.16 ORY19155.1 - 0.0014 17.7 0.1 0.0022 17.0 0.1 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_25 PF13481.6 ORY19155.1 - 0.0071 15.9 0.1 0.014 15.0 0.1 1.4 1 0 0 1 1 1 1 AAA domain CBP_BcsQ PF06564.12 ORY19155.1 - 0.014 14.9 0.2 0.041 13.3 0.1 1.7 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsQ APS_kinase PF01583.20 ORY19155.1 - 0.02 14.8 0.0 0.032 14.1 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase NB-ARC PF00931.22 ORY19155.1 - 0.049 12.8 0.1 0.074 12.2 0.1 1.2 1 0 0 1 1 1 0 NB-ARC domain Zeta_toxin PF06414.12 ORY19155.1 - 0.056 12.7 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin RsgA_GTPase PF03193.16 ORY19155.1 - 0.084 12.8 2.1 0.11 12.4 1.1 1.7 2 0 0 2 2 2 0 RsgA GTPase CLP1_P PF16575.5 ORY19155.1 - 0.14 12.0 0.0 0.36 10.6 0.0 1.7 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Caskin1-CID PF16600.5 ORY19156.1 - 2.2 8.9 5.9 0.24 12.0 1.3 1.7 2 0 0 2 2 2 0 Caskin1 CASK-interaction domain Cyclase PF04199.13 ORY19160.1 - 3e-25 89.0 0.0 3.2e-25 88.9 0.0 1.0 1 0 0 1 1 1 1 Putative cyclase Raptor_N PF14538.6 ORY19160.1 - 0.048 13.6 0.0 0.062 13.3 0.0 1.2 1 0 0 1 1 1 0 Raptor N-terminal CASPase like domain Mito_fiss_reg PF05308.11 ORY19160.1 - 9.6 6.2 6.5 12 5.9 6.5 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator F-box-like PF12937.7 ORY19161.1 - 6.6e-05 22.7 0.1 0.00023 21.0 0.0 2.1 2 0 0 2 2 2 1 F-box-like Pkinase PF00069.25 ORY19162.1 - 2.7e-25 89.2 0.0 5.8e-25 88.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain zf-C2H2 PF00096.26 ORY19162.1 - 0.002 18.5 0.2 0.002 18.5 0.2 3.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type SDA1 PF05285.12 ORY19162.1 - 0.0047 16.4 5.3 0.007 15.8 5.3 1.2 1 0 0 1 1 1 1 SDA1 zf-C2H2_4 PF13894.6 ORY19162.1 - 0.1 13.5 0.3 0.1 13.5 0.3 4.2 4 0 0 4 4 4 0 C2H2-type zinc finger NOA36 PF06524.12 ORY19162.1 - 8.3 5.6 12.4 14 4.8 12.4 1.3 1 0 0 1 1 1 0 NOA36 protein Adeno_E3_CR2 PF02439.15 ORY19165.1 - 0.0034 17.1 3.3 0.0066 16.2 3.3 1.4 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 SKG6 PF08693.10 ORY19165.1 - 0.013 14.9 3.1 0.023 14.1 3.1 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain S1FA PF04689.13 ORY19165.1 - 0.036 14.2 0.1 0.063 13.4 0.1 1.3 1 0 0 1 1 1 0 DNA binding protein S1FA Gly-zipper_Omp PF13488.6 ORY19165.1 - 0.055 13.5 6.2 0.1 12.6 6.2 1.4 1 0 0 1 1 1 0 Glycine zipper EphA2_TM PF14575.6 ORY19165.1 - 0.058 14.3 0.1 0.11 13.4 0.1 1.6 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Syndecan PF01034.20 ORY19165.1 - 0.06 13.3 0.8 0.12 12.3 0.8 1.4 1 0 0 1 1 1 0 Syndecan domain DAP10 PF07213.11 ORY19165.1 - 0.079 12.9 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 DAP10 membrane protein DUF2207 PF09972.9 ORY19165.1 - 0.14 10.9 0.0 0.17 10.6 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) PDGLE PF13190.6 ORY19165.1 - 0.22 11.4 0.7 0.5 10.3 0.1 1.8 2 0 0 2 2 2 0 PDGLE domain VSP PF03302.13 ORY19168.1 - 0.0021 17.0 0.5 0.0028 16.6 0.5 1.1 1 0 0 1 1 1 1 Giardia variant-specific surface protein LapA_dom PF06305.11 ORY19168.1 - 0.2 11.5 0.2 0.48 10.3 0.2 1.6 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Mucin PF01456.17 ORY19168.1 - 0.32 11.0 12.6 0.67 9.9 12.6 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein DDR PF08841.10 ORY19169.1 - 0.0033 16.5 0.4 0.013 14.5 0.2 1.9 1 1 1 2 2 2 1 Diol dehydratase reactivase ATPase-like domain Mad3_BUB1_I_2 PF17014.5 ORY19169.1 - 0.0033 17.6 0.0 0.0079 16.3 0.0 1.6 1 0 0 1 1 1 1 Putative Mad3/BUB1 like region 1 protein HSP70 PF00012.20 ORY19169.1 - 0.039 12.2 0.0 0.14 10.3 0.0 1.8 1 1 0 1 1 1 0 Hsp70 protein SNX17_FERM_C PF18116.1 ORY19169.1 - 0.14 12.3 0.1 19 5.4 0.1 2.4 2 0 0 2 2 2 0 Sorting Nexin 17 FERM C-terminal domain Phage_holin_3_6 PF07332.11 ORY19171.1 - 0.0024 17.9 0.2 0.0031 17.5 0.2 1.1 1 0 0 1 1 1 1 Putative Actinobacterial Holin-X, holin superfamily III CorA PF01544.18 ORY19171.1 - 0.01 15.2 2.8 0.013 14.9 2.8 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein ESSS PF10183.9 ORY19171.1 - 0.035 14.3 1.1 0.053 13.7 1.1 1.4 1 1 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) p450 PF00067.22 ORY19172.1 - 0.02 13.6 3.2 0.45 9.2 0.3 2.0 1 1 1 2 2 2 0 Cytochrome P450 Helo_like_N PF17111.5 ORY19176.1 - 2.7e-12 46.5 5.4 1.5e-07 31.0 0.1 2.6 1 1 1 2 2 2 2 Fungal N-terminal domain of STAND proteins DUF1098 PF06497.11 ORY19176.1 - 0.0036 17.7 1.2 0.023 15.2 0.1 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1098) SesA PF17107.5 ORY19176.1 - 0.041 14.1 1.2 0.11 12.7 0.6 2.0 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Ubiquitin_5 PF18037.1 ORY19176.1 - 0.045 14.1 0.3 0.16 12.3 0.0 2.1 2 0 0 2 2 2 0 Ubiquitin-like domain DUF2312 PF10073.9 ORY19176.1 - 0.077 12.6 0.2 0.27 10.9 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2312) ubiquitin PF00240.23 ORY19176.1 - 0.097 12.4 0.1 0.45 10.3 0.0 2.3 2 0 0 2 2 2 0 Ubiquitin family MFS_1 PF07690.16 ORY19177.1 - 7.5e-50 169.8 55.1 6.4e-49 166.8 52.4 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF1118 PF06549.12 ORY19177.1 - 0.43 10.9 5.1 2.9 8.2 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1118) DNA_pol_A_exo1 PF01612.20 ORY19178.1 - 0.0062 16.3 0.2 0.058 13.1 0.0 2.1 2 0 0 2 2 2 1 3'-5' exonuclease LSM PF01423.22 ORY19180.1 - 1.8e-07 30.8 0.0 2.3e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 ORY19180.1 - 0.013 15.6 0.0 0.017 15.2 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain PEX11 PF05648.14 ORY19181.1 - 0.0013 18.2 0.1 0.0031 17.0 0.1 1.5 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Ribosomal_L27 PF01016.19 ORY19182.1 - 2.1e-28 98.2 0.2 3.7e-28 97.4 0.2 1.4 1 0 0 1 1 1 1 Ribosomal L27 protein RRN9 PF10680.9 ORY19182.1 - 0.024 14.9 0.2 0.05 13.9 0.2 1.6 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor ATP-synt_ab PF00006.25 ORY19185.1 - 9.5e-110 365.3 0.0 1.3e-109 364.8 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 ORY19185.1 - 4.1e-46 155.8 0.0 9.5e-46 154.6 0.0 1.7 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 ORY19185.1 - 2.2e-14 53.7 1.6 4.6e-14 52.7 1.6 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Dynamin_M PF01031.20 ORY19186.1 - 2e-99 332.4 0.0 3.5e-99 331.6 0.0 1.4 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 ORY19186.1 - 6.7e-57 192.2 0.5 1.4e-56 191.1 0.1 1.8 2 0 0 2 2 2 1 Dynamin family GED PF02212.18 ORY19186.1 - 1e-29 102.5 5.8 2.2e-29 101.4 5.8 1.6 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 ORY19186.1 - 1.8e-05 24.8 0.4 7.9e-05 22.7 0.4 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase NAAA-beta PF15508.6 ORY19187.1 - 3e-12 46.7 0.2 6.6e-12 45.6 0.2 1.6 1 0 0 1 1 1 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase CoA_transf_3 PF02515.17 ORY19188.1 - 5.5e-64 216.6 0.0 1.2e-63 215.5 0.0 1.5 1 1 0 1 1 1 1 CoA-transferase family III AUX_IAA PF02309.16 ORY19188.1 - 0.061 13.2 0.0 0.64 9.8 0.0 2.0 1 1 1 2 2 2 0 AUX/IAA family Cu-oxidase_2 PF07731.14 ORY19189.1 - 2.7e-45 153.5 5.5 6.7e-39 132.8 0.1 3.4 3 1 0 3 3 3 3 Multicopper oxidase Cu-oxidase_3 PF07732.15 ORY19189.1 - 1.5e-40 138.0 8.0 9.8e-39 132.1 0.6 3.4 4 1 0 4 4 4 2 Multicopper oxidase Cu-oxidase PF00394.22 ORY19189.1 - 3.2e-36 124.9 1.7 5.9e-33 114.2 0.7 3.1 3 0 0 3 3 3 2 Multicopper oxidase ATP_transf PF09830.9 ORY19190.1 - 4.7e-09 36.3 0.1 8.2e-09 35.5 0.1 1.4 1 0 0 1 1 1 1 ATP adenylyltransferase Cation_ATPase_N PF00690.26 ORY19196.1 - 2.3e-15 56.0 0.0 3.1e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus E1-E2_ATPase PF00122.20 ORY19197.1 - 8.1e-35 120.0 20.6 1e-28 100.1 0.1 3.6 3 1 1 4 4 4 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 ORY19197.1 - 5e-23 81.7 4.4 5e-23 81.7 4.4 2.4 2 1 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 ORY19197.1 - 3.5e-19 69.9 0.6 3.7e-16 60.1 0.1 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 ORY19197.1 - 1.8e-13 50.3 0.0 4.4e-13 49.1 0.0 1.7 1 1 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 ORY19197.1 - 3.9e-05 23.5 3.8 3.9e-05 23.5 3.8 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2463 PF09591.10 ORY19197.1 - 0.015 15.2 1.2 0.04 13.8 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2463) S4_2 PF13275.6 ORY19197.1 - 0.12 12.2 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 S4 domain Rad9_Rad53_bind PF08605.10 ORY19198.1 - 1.3e-15 57.8 0.0 2.4e-15 56.9 0.0 1.4 1 0 0 1 1 1 1 Fungal Rad9-like Rad53-binding Tudor_3 PF18115.1 ORY19198.1 - 5.4e-14 51.8 0.0 1.7e-13 50.2 0.0 1.9 2 0 0 2 2 2 1 DNA repair protein Crb2 Tudor domain BRCT PF00533.26 ORY19198.1 - 6.9e-09 36.0 0.0 1.4e-08 35.0 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 ORY19198.1 - 0.00032 21.0 0.0 0.0015 18.9 0.0 2.2 2 1 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain Sdh_cyt PF01127.22 ORY19199.1 - 3.9e-25 88.2 4.1 4.8e-25 87.9 4.1 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit WD40 PF00400.32 ORY19200.1 - 4.3e-06 27.4 2.9 0.3 12.0 0.0 4.4 4 0 0 4 4 4 2 WD domain, G-beta repeat Nucleoporin_N PF08801.11 ORY19200.1 - 0.00021 20.2 0.0 0.0023 16.8 0.0 2.3 2 0 0 2 2 2 1 Nup133 N terminal like DUF3328 PF11807.8 ORY19202.1 - 4.3e-26 92.0 3.8 5.6e-26 91.7 3.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) 7tm_1 PF00001.21 ORY19203.1 - 0.23 10.8 7.0 0.43 9.8 7.0 1.5 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) SQHop_cyclase_C PF13243.6 ORY19205.1 - 9.6e-52 176.1 0.0 3.4e-49 167.7 0.1 2.1 2 0 0 2 2 2 2 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 ORY19205.1 - 1.4e-43 149.1 2.7 2.2e-37 128.8 0.1 4.3 2 1 2 4 4 4 4 Squalene-hopene cyclase N-terminal domain Prenyltrans PF00432.21 ORY19205.1 - 8.1e-23 79.9 14.4 8.3e-08 31.8 0.0 5.4 6 0 0 6 6 6 3 Prenyltransferase and squalene oxidase repeat TED_complement PF07678.14 ORY19205.1 - 9.1e-05 21.6 0.0 0.013 14.5 0.0 3.2 3 1 0 3 3 3 1 A-macroglobulin TED domain Pec_lyase PF09492.10 ORY19205.1 - 0.0011 18.4 0.0 8.5 5.6 0.0 4.2 3 1 1 4 4 4 1 Pectic acid lyase Chromadorea_ALT PF05535.12 ORY19205.1 - 0.078 13.2 0.2 0.18 12.0 0.2 1.6 1 0 0 1 1 1 0 Chromadorea ALT protein Gemini_C4 PF01492.17 ORY19206.1 - 1.6 8.7 8.9 0.66 9.9 4.3 2.3 2 0 0 2 2 2 0 Geminivirus C4 protein DUF1295 PF06966.12 ORY19207.1 - 7.1e-18 65.0 0.2 9e-18 64.6 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ERG4_ERG24 PF01222.17 ORY19207.1 - 8e-08 31.5 0.3 1.1e-07 31.0 0.3 1.3 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Steroid_dh PF02544.16 ORY19207.1 - 2.6e-07 30.8 0.1 3.4e-07 30.4 0.1 1.1 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DNA_ligase_A_M PF01068.21 ORY19208.1 - 2.5e-24 86.0 0.0 5.2e-24 85.0 0.0 1.5 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 ORY19208.1 - 4.2e-21 76.0 0.0 1.1e-20 74.7 0.0 1.8 1 0 0 1 1 1 1 DNA ligase N terminus Pkinase PF00069.25 ORY19209.1 - 1.7e-13 50.5 0.0 2.7e-12 46.6 0.0 2.4 1 1 0 1 1 1 1 Protein kinase domain MFS_1 PF07690.16 ORY19211.1 - 1.3e-21 76.9 23.9 1.3e-21 76.9 23.9 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily PfkB PF00294.24 ORY19212.1 - 5.2e-56 190.2 3.4 6.4e-56 189.9 3.4 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase EMP24_GP25L PF01105.24 ORY19214.1 - 4e-48 163.8 2.1 4.5e-48 163.6 2.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DIX PF00778.17 ORY19214.1 - 0.031 14.1 0.1 0.23 11.3 0.1 2.3 2 0 0 2 2 2 0 DIX domain Macoilin PF09726.9 ORY19214.1 - 0.033 12.8 0.0 0.036 12.6 0.0 1.0 1 0 0 1 1 1 0 Macoilin family USP7_ICP0_bdg PF12436.8 ORY19215.1 - 1.7e-77 260.0 0.0 3.5e-75 252.4 0.0 2.5 2 0 0 2 2 2 2 ICP0-binding domain of Ubiquitin-specific protease 7 UCH PF00443.29 ORY19215.1 - 7e-48 163.3 2.0 7e-48 163.3 2.0 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.6 ORY19215.1 - 2e-45 155.0 9.1 2e-43 148.5 7.9 3.2 2 1 0 2 2 2 1 Ubiquitin-specific protease C-terminal UCH_1 PF13423.6 ORY19215.1 - 1.5e-21 77.3 0.5 3.9e-21 76.0 0.1 1.9 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.26 ORY19215.1 - 8.7e-08 32.3 0.0 3.6e-07 30.3 0.0 2.2 2 0 0 2 2 2 1 MATH domain Rad60-SLD PF11976.8 ORY19215.1 - 0.0056 16.5 1.9 0.41 10.5 0.0 2.9 3 0 0 3 3 3 1 Ubiquitin-2 like Rad60 SUMO-like BCDHK_Adom3 PF10436.9 ORY19217.1 - 3.6e-45 153.7 0.3 6.2e-45 152.9 0.0 1.5 2 0 0 2 2 2 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 ORY19217.1 - 2.1e-06 28.2 0.0 1.8e-05 25.2 0.0 2.1 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 ORY19217.1 - 0.04 13.7 0.0 0.081 12.8 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Neur_chan_memb PF02932.16 ORY19218.1 - 0.13 12.3 3.9 0.28 11.2 3.9 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Pmp3 PF01679.17 ORY19219.1 - 2.2e-21 75.8 8.9 2.7e-21 75.5 8.9 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Ribosomal_L19 PF01245.20 ORY19221.1 - 3.3e-14 52.7 0.2 4.9e-14 52.2 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L19 NmrA PF05368.13 ORY19222.1 - 6.2e-70 235.4 0.0 7.6e-70 235.1 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ORY19222.1 - 6.6e-08 32.6 0.0 9.8e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Asparaginase PF00710.20 ORY19223.1 - 6.9e-59 198.6 0.0 1.1e-58 197.9 0.0 1.3 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 ORY19223.1 - 9.6e-29 99.9 0.0 2.6e-28 98.5 0.1 1.7 2 0 0 2 2 2 1 Glutaminase/Asparaginase C-terminal domain NAP PF00956.18 ORY19225.1 - 2.1e-28 99.2 8.9 1.5e-26 93.2 5.6 2.1 1 1 1 2 2 2 2 Nucleosome assembly protein (NAP) BUD22 PF09073.10 ORY19225.1 - 0.12 11.7 15.0 0.16 11.3 15.0 1.2 1 0 0 1 1 1 0 BUD22 RPA43_OB PF17875.1 ORY19225.1 - 7.2 7.3 7.9 1.1 9.9 3.3 2.0 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I AIM3 PF17096.5 ORY19225.1 - 9.1 7.3 12.4 7.1 7.6 1.3 3.0 3 0 0 3 3 3 0 Altered inheritance of mitochondria protein 3 GrpE PF01025.19 ORY19226.1 - 4.7 6.8 5.8 6.2 6.5 0.2 2.8 1 1 0 2 2 2 0 GrpE TGT PF01702.18 ORY19227.1 - 3.9e-60 203.9 0.0 4.8e-60 203.6 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase PBP PF01161.20 ORY19229.1 - 3.3e-12 46.9 0.0 5e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Glyco_hydro_3_C PF01915.22 ORY19231.1 - 3.7e-44 151.1 0.0 5.9e-44 150.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 ORY19231.1 - 1.1e-37 130.2 0.0 1.7e-37 129.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 ORY19231.1 - 3.2e-23 81.6 0.0 5.6e-23 80.8 0.0 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF3586 PF12131.8 ORY19232.1 - 0.44 10.8 4.6 0.38 11.0 3.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3586) DCP2 PF05026.13 ORY19235.1 - 0.037 14.3 0.3 8.5 6.8 0.0 2.2 2 0 0 2 2 2 0 Dcp2, box A domain DUF2884 PF11101.8 ORY19235.1 - 8 5.9 12.4 5.3 6.5 11.0 1.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2884) PQ-loop PF04193.14 ORY19237.1 - 4.5e-23 80.8 2.8 1.5e-14 53.5 0.1 2.4 2 0 0 2 2 2 2 PQ loop repeat ER_lumen_recept PF00810.18 ORY19237.1 - 0.29 11.9 6.7 0.44 11.4 6.7 1.3 1 0 0 1 1 1 0 ER lumen protein retaining receptor Ac76 PF05814.11 ORY19237.1 - 5.7 7.0 6.5 0.58 10.2 0.6 2.2 2 1 0 2 2 2 0 Orf76 (Ac76) GGACT PF06094.12 ORY19238.1 - 2.4e-15 57.2 0.0 5.4e-15 56.1 0.0 1.6 1 1 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like Peptidase_C48 PF02902.19 ORY19239.1 - 1.3e-30 106.9 0.0 6.4e-30 104.6 0.0 2.1 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain IF4E PF01652.18 ORY19240.1 - 1.1e-53 181.3 0.2 1.7e-53 180.7 0.2 1.3 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Podoplanin PF05808.11 ORY19240.1 - 0.49 10.5 2.9 0.29 11.2 0.7 1.7 2 0 0 2 2 2 0 Podoplanin IPP-2 PF04979.14 ORY19241.1 - 8.3e-25 88.1 16.1 1.6e-24 87.1 16.1 1.4 1 0 0 1 1 1 1 Protein phosphatase inhibitor 2 (IPP-2) Peptidase_M18 PF02127.15 ORY19242.1 - 1.2e-133 446.1 0.0 1.4e-133 445.8 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Pex14_N PF04695.13 ORY19243.1 - 0.033 14.9 3.1 0.042 14.5 3.1 1.4 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CCDC106 PF15794.5 ORY19243.1 - 0.051 13.3 0.5 0.65 9.7 0.0 2.0 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 DUF3915 PF13054.6 ORY19245.1 - 0.03 14.3 0.0 0.047 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) LapA_dom PF06305.11 ORY19245.1 - 0.035 13.9 0.7 0.083 12.7 0.3 1.8 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain NAD_binding_4 PF07993.12 ORY19246.1 - 1.1e-05 24.7 0.0 1.4e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein IstB_IS21_ATP PF08483.11 ORY19247.1 - 0.15 12.0 0.3 0.29 11.1 0.3 1.5 1 0 0 1 1 1 0 IstB-like ATP binding N-terminal tRNA-synt_1e PF01406.19 ORY19248.1 - 1.5e-115 385.7 0.0 2.9e-115 384.8 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 ORY19248.1 - 0.0051 15.6 0.1 0.95 8.1 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class I (M) 40S_SA_C PF16122.5 ORY19248.1 - 1.1 10.6 7.9 0.67 11.3 4.1 2.6 2 0 0 2 2 2 0 40S ribosomal protein SA C-terminus DUF1682 PF07946.14 ORY19248.1 - 1.2 8.2 9.6 2.4 7.3 9.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) GCD14 PF08704.10 ORY19249.1 - 2.3e-61 207.6 0.0 3.1e-21 76.2 0.0 3.8 2 2 1 3 3 3 3 tRNA methyltransferase complex GCD14 subunit CMAS PF02353.20 ORY19249.1 - 0.15 11.4 0.0 0.32 10.2 0.0 1.5 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase Borrelia_P83 PF05262.11 ORY19249.1 - 8 4.8 6.6 12 4.3 6.6 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein PhoD PF09423.10 ORY19250.1 - 4.4e-43 147.6 0.0 9.4e-43 146.6 0.0 1.5 1 1 0 1 1 1 1 PhoD-like phosphatase Pur_ac_phosph_N PF16656.5 ORY19250.1 - 0.00027 21.4 0.7 0.00061 20.3 0.1 1.9 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain PhoD_N PF16655.5 ORY19250.1 - 0.0013 19.2 0.1 0.003 18.1 0.1 1.6 1 0 0 1 1 1 1 PhoD-like phosphatase, N-terminal domain fn3 PF00041.21 ORY19250.1 - 0.0078 16.5 0.4 0.034 14.5 0.2 2.2 2 0 0 2 2 2 1 Fibronectin type III domain MFS_1 PF07690.16 ORY19251.1 - 2.3e-21 76.1 49.0 2.3e-21 76.1 49.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily CarboxypepD_reg PF13620.6 ORY19252.1 - 0.0075 16.5 0.0 0.01 16.1 0.0 1.2 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain F-box-like PF12937.7 ORY19253.1 - 0.024 14.5 1.1 0.057 13.3 1.1 1.7 1 0 0 1 1 1 0 F-box-like Ferric_reduct PF01794.19 ORY19254.1 - 1.3e-19 70.5 19.7 1.3e-19 70.5 19.7 2.6 2 1 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 ORY19254.1 - 3.5e-14 53.2 0.0 5.6e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 ORY19254.1 - 1.2e-12 47.9 0.0 3.6e-12 46.3 0.0 1.8 1 0 0 1 1 1 1 FAD-binding domain DUF4405 PF14358.6 ORY19254.1 - 0.00074 20.0 18.3 0.021 15.4 1.6 3.7 3 0 0 3 3 3 3 Domain of unknown function (DUF4405) baeRF_family12 PF18856.1 ORY19254.1 - 0.098 13.2 0.0 0.21 12.2 0.0 1.5 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 12 E1-E2_ATPase PF00122.20 ORY19254.1 - 0.49 9.9 2.2 0.56 9.7 0.7 1.9 2 0 0 2 2 2 0 E1-E2 ATPase Ctr PF04145.15 ORY19255.1 - 2.2e-24 86.7 4.5 2.8e-24 86.4 4.5 1.1 1 0 0 1 1 1 1 Ctr copper transporter family zf-RING_2 PF13639.6 ORY19258.1 - 6e-07 29.7 5.7 1.1e-06 28.8 5.7 1.5 1 0 0 1 1 1 1 Ring finger domain zf-ANAPC11 PF12861.7 ORY19258.1 - 6.6e-05 22.9 1.2 9.8e-05 22.3 1.2 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 ORY19258.1 - 0.0084 16.3 8.8 0.086 13.0 7.9 2.7 2 1 0 2 2 2 1 FANCL C-terminal domain Prok-RING_1 PF14446.6 ORY19258.1 - 0.035 14.0 3.2 0.035 14.0 3.2 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 zf-rbx1 PF12678.7 ORY19258.1 - 0.06 13.6 3.3 0.13 12.6 3.3 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 ORY19258.1 - 0.066 13.1 1.0 12 5.8 0.0 2.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 ORY19258.1 - 0.14 12.1 6.4 0.32 11.0 6.4 1.7 1 0 0 1 1 1 0 zinc-RING finger domain IBR PF01485.21 ORY19258.1 - 0.21 11.9 7.8 0.44 10.8 6.7 2.0 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain RINGv PF12906.7 ORY19258.1 - 0.67 10.1 6.1 1.2 9.3 6.1 1.4 1 0 0 1 1 1 0 RING-variant domain zf-Di19 PF05605.12 ORY19258.1 - 1.1 9.7 4.2 11 6.4 0.1 2.6 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C3HC4_3 PF13920.6 ORY19258.1 - 8.6 6.3 8.8 1.6e+02 2.3 8.7 2.4 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Glyco_hydro_15 PF00723.21 ORY19259.1 - 5.7e-92 308.8 1.7 7.1e-92 308.5 1.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.19 ORY19259.1 - 6e-21 74.2 0.0 1.5e-20 72.8 0.0 1.7 1 0 0 1 1 1 1 Starch binding domain MerC PF03203.14 ORY19260.1 - 4.1 7.9 15.6 10 6.6 0.5 3.5 2 1 0 3 3 3 0 MerC mercury resistance protein Glyco_transf_21 PF13506.6 ORY19261.1 - 2.3e-11 43.5 0.0 8.4e-05 22.1 0.0 2.9 3 0 0 3 3 3 2 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 ORY19261.1 - 9.9e-06 25.6 0.0 2.4e-05 24.3 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 ORY19261.1 - 0.00018 21.3 0.0 0.005 16.7 0.0 2.4 1 1 0 1 1 1 1 Glycosyl transferase family 2 KleE PF17394.2 ORY19261.1 - 1.7 8.9 6.3 2.8 8.2 0.1 2.7 2 0 0 2 2 2 0 Uncharacterized KleE stable inheritance protein FAD_binding_4 PF01565.23 ORY19264.1 - 5.5e-18 65.0 0.1 8e-18 64.5 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain adh_short PF00106.25 ORY19265.1 - 0.035 13.6 0.0 0.047 13.1 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase KR PF08659.10 ORY19265.1 - 0.054 13.4 0.0 0.063 13.2 0.0 1.1 1 0 0 1 1 1 0 KR domain Noelin-1 PF12308.8 ORY19265.1 - 0.063 13.3 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Neurogenesis glycoprotein UbiA PF01040.18 ORY19266.1 - 5.8e-08 32.3 0.2 6.9e-08 32.1 0.2 1.0 1 0 0 1 1 1 1 UbiA prenyltransferase family HAT_KAT11 PF08214.11 ORY19267.1 - 1.9e-97 326.7 0.0 2.7e-97 326.2 0.0 1.2 1 0 0 1 1 1 1 Histone acetylation protein Ribonucleas_3_3 PF14622.6 ORY19268.1 - 4.1e-14 52.8 0.0 5.5e-14 52.4 0.0 1.2 1 1 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 ORY19268.1 - 8.3e-06 26.4 0.0 1.2e-05 25.8 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease III domain DUF2756 PF10956.8 ORY19269.1 - 0.04 14.4 0.0 0.071 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2756) Glyco_hydro_72 PF03198.14 ORY19270.1 - 3e-121 404.5 0.9 3.8e-121 404.2 0.9 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Glyco_hydro_2_C PF02836.17 ORY19270.1 - 3.3e-05 23.2 0.0 4.3e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Cellulase PF00150.18 ORY19270.1 - 0.00062 19.3 0.5 0.016 14.7 0.5 2.4 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Methyltransf_23 PF13489.6 ORY19271.1 - 1.2e-20 74.0 0.0 1.8e-20 73.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY19271.1 - 2.1e-10 41.2 0.0 4.8e-10 40.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY19271.1 - 1.2e-09 38.8 0.0 8.7e-09 36.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY19271.1 - 3.5e-09 36.6 0.0 2e-08 34.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY19271.1 - 5.7e-07 30.1 0.0 1.1e-06 29.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 ORY19271.1 - 0.028 13.9 0.0 0.071 12.6 0.0 1.7 2 0 0 2 2 2 0 Putative methyltransferase CheR PF01739.18 ORY19271.1 - 0.052 13.0 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain MTS PF05175.14 ORY19271.1 - 0.07 12.7 0.0 0.47 10.0 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase small domain DUF938 PF06080.12 ORY19271.1 - 0.095 12.5 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Ubie_methyltran PF01209.18 ORY19271.1 - 0.13 11.5 0.0 0.31 10.3 0.0 1.7 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family adh_short_C2 PF13561.6 ORY19273.1 - 2.4e-60 204.0 0.1 2.7e-60 203.8 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY19273.1 - 7.1e-41 139.8 0.3 8.5e-41 139.6 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORY19273.1 - 2.7e-15 56.8 0.2 3.8e-15 56.3 0.2 1.2 1 0 0 1 1 1 1 KR domain Spore_IV_A PF09547.10 ORY19273.1 - 0.049 12.6 0.0 0.069 12.1 0.0 1.1 1 0 0 1 1 1 0 Stage IV sporulation protein A (spore_IV_A) Polysacc_synt_2 PF02719.15 ORY19273.1 - 0.06 12.5 0.1 0.082 12.0 0.1 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Methyltransf_32 PF13679.6 ORY19274.1 - 3.3e-22 79.2 2.4 3.8e-21 75.7 2.4 2.2 1 1 0 1 1 1 1 Methyltransferase domain Syntaxin-6_N PF09177.11 ORY19275.1 - 8e-28 96.9 1.4 1.9e-27 95.7 0.3 1.9 2 0 0 2 2 2 1 Syntaxin 6, N-terminal RRF PF01765.19 ORY19275.1 - 0.00013 22.0 3.1 0.22 11.5 0.3 2.8 2 1 1 3 3 3 2 Ribosome recycling factor SNARE PF05739.19 ORY19275.1 - 0.0025 17.8 1.1 0.0048 16.9 0.2 2.0 2 0 0 2 2 2 1 SNARE domain YtxH PF12732.7 ORY19275.1 - 0.007 16.9 2.3 1.4 9.5 2.3 3.0 1 1 0 1 1 1 1 YtxH-like protein Prominin PF05478.11 ORY19275.1 - 0.0084 14.1 0.2 0.22 9.5 0.2 2.1 1 1 0 1 1 1 1 Prominin Use1 PF09753.9 ORY19275.1 - 0.01 15.5 0.2 0.032 14.0 0.0 1.6 1 1 0 2 2 2 0 Membrane fusion protein Use1 Atg14 PF10186.9 ORY19275.1 - 0.015 14.4 0.1 0.017 14.2 0.1 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Laminin_II PF06009.12 ORY19275.1 - 0.016 15.3 1.5 1.6 8.8 0.3 2.3 2 0 0 2 2 2 0 Laminin Domain II KxDL PF10241.9 ORY19275.1 - 0.018 15.3 0.7 16 5.9 0.0 3.5 4 0 0 4 4 4 0 Uncharacterized conserved protein DUF4795 PF16043.5 ORY19275.1 - 0.027 14.1 0.4 0.027 14.1 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) DUF948 PF06103.11 ORY19275.1 - 0.029 14.6 6.7 3.6 7.9 0.6 3.6 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) NPV_P10 PF05531.12 ORY19275.1 - 0.054 14.0 2.7 12 6.4 0.0 3.3 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF883 PF05957.13 ORY19275.1 - 0.09 13.4 4.4 7.8 7.2 0.0 3.2 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) Syntaxin_2 PF14523.6 ORY19275.1 - 0.096 13.1 1.1 0.54 10.7 0.6 2.3 1 1 1 2 2 2 0 Syntaxin-like protein DUF1664 PF07889.12 ORY19275.1 - 0.1 12.7 5.0 1.2 9.2 1.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) OmpH PF03938.14 ORY19275.1 - 0.1 12.9 8.0 4 7.8 3.4 2.5 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) DUF2205 PF10224.9 ORY19275.1 - 0.12 12.3 0.1 0.12 12.3 0.1 2.6 3 0 0 3 3 3 0 Short coiled-coil protein Fez1 PF06818.15 ORY19275.1 - 0.15 12.5 3.7 0.21 12.0 3.7 1.3 1 0 0 1 1 1 0 Fez1 Focal_AT PF03623.13 ORY19275.1 - 0.21 11.6 2.0 6.7 6.7 0.1 2.6 2 1 1 3 3 3 0 Focal adhesion targeting region DUF2207 PF09972.9 ORY19275.1 - 0.22 10.3 0.0 0.36 9.5 0.0 1.5 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) T3SS_needle_F PF09392.10 ORY19275.1 - 0.22 11.7 0.8 23 5.3 0.0 3.1 3 0 0 3 3 3 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF HMMR_N PF15905.5 ORY19275.1 - 0.34 10.4 6.5 0.051 13.1 1.4 1.8 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal DUF4164 PF13747.6 ORY19275.1 - 0.37 11.1 6.9 4.8 7.5 2.5 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4164) Integrin_b_cyt PF08725.11 ORY19275.1 - 0.4 10.4 1.5 0.92 9.2 1.5 1.6 1 0 0 1 1 1 0 Integrin beta cytoplasmic domain Spc7 PF08317.11 ORY19275.1 - 0.44 9.4 6.8 0.22 10.4 1.4 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein APG6_N PF17675.1 ORY19275.1 - 0.54 10.8 10.4 1.6 9.3 2.6 2.5 2 1 0 2 2 2 0 Apg6 coiled-coil region GAS PF13851.6 ORY19275.1 - 0.65 9.3 5.6 0.52 9.6 0.8 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DotU PF09850.9 ORY19275.1 - 0.82 9.3 5.0 1.1 9.0 0.3 2.9 2 2 1 3 3 3 0 Type VI secretion system protein DotU STAT_alpha PF01017.20 ORY19275.1 - 1.4 8.8 6.7 31 4.4 6.8 2.2 1 1 0 1 1 1 0 STAT protein, all-alpha domain YabA PF06156.13 ORY19275.1 - 1.7 9.3 5.1 2.8 8.6 1.5 2.4 2 1 0 2 2 2 0 Initiation control protein YabA GCIP PF13324.6 ORY19275.1 - 3.9 7.0 11.8 13 5.3 11.8 2.0 1 1 0 1 1 1 0 Grap2 and cyclin-D-interacting DUF16 PF01519.16 ORY19275.1 - 6.8 7.2 8.0 9.9 6.7 0.7 2.3 1 1 0 2 2 2 0 Protein of unknown function DUF16 UPF0242 PF06785.11 ORY19275.1 - 7.3 6.6 14.1 1 9.4 0.4 2.9 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus DUF2189 PF09955.9 ORY19276.1 - 2.2 8.5 6.0 0.38 11.0 0.7 2.1 1 1 1 2 2 2 0 Predicted integral membrane protein (DUF2189) Ribosomal_L1 PF00687.21 ORY19277.1 - 7.8e-32 110.7 0.0 9.9e-32 110.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family COG2 PF06148.11 ORY19278.1 - 2e-33 115.3 1.1 3e-33 114.7 0.2 1.7 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps51 PF08700.11 ORY19278.1 - 6.6e-05 22.9 0.1 0.00016 21.7 0.1 1.6 1 0 0 1 1 1 1 Vps51/Vps67 COG5 PF10392.9 ORY19278.1 - 0.00091 19.4 0.4 0.002 18.3 0.0 1.8 2 0 0 2 2 2 1 Golgi transport complex subunit 5 CDT1 PF08839.11 ORY19278.1 - 0.11 12.8 0.1 1.3 9.3 0.0 2.1 2 0 0 2 2 2 0 DNA replication factor CDT1 like NUDIX-like PF09296.11 ORY19279.1 - 1.6e-15 57.6 0.0 4.7e-15 56.1 0.0 1.8 2 0 0 2 2 2 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.11 ORY19279.1 - 0.0001 21.9 1.2 0.00018 21.1 1.2 1.4 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain PALP PF00291.25 ORY19280.1 - 5.9e-65 219.6 0.1 7.4e-65 219.3 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Cnd3 PF12719.7 ORY19281.1 - 4.9e-82 275.4 1.3 1.1e-80 271.0 0.8 2.5 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT PF02985.22 ORY19281.1 - 3.1e-08 33.2 3.5 0.2 12.0 0.0 6.1 5 0 0 5 5 5 3 HEAT repeat HEAT_2 PF13646.6 ORY19281.1 - 7.6e-06 26.2 2.7 0.0011 19.3 0.3 4.5 4 1 1 5 5 5 2 HEAT repeats Cnd1 PF12717.7 ORY19281.1 - 0.0012 18.9 2.5 1 9.4 0.0 4.5 5 1 1 6 6 6 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 ORY19281.1 - 0.08 13.5 4.1 0.44 11.1 0.1 3.8 4 0 0 4 4 4 0 HEAT-like repeat RTP1_C1 PF10363.9 ORY19281.1 - 0.1 12.8 0.1 0.69 10.1 0.0 2.5 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 zf-RanBP PF00641.18 ORY19282.1 - 6.9e-20 70.1 9.7 1.9e-10 39.9 2.4 2.3 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others RRM_1 PF00076.22 ORY19282.1 - 9.8e-08 31.7 0.0 2.2e-07 30.6 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNase_T PF00929.24 ORY19282.1 - 8.7e-07 29.6 0.0 1.3e-06 29.1 0.0 1.2 1 0 0 1 1 1 1 Exonuclease F-box-like PF12937.7 ORY19283.1 - 0.0016 18.3 0.0 0.0056 16.5 0.0 2.0 1 1 0 1 1 1 1 F-box-like HET PF06985.11 ORY19284.1 - 5.9e-21 75.4 0.0 6.4e-21 75.2 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PH PF00169.29 ORY19285.1 - 1.2e-06 29.0 0.3 2.3e-06 28.0 0.3 1.5 1 0 0 1 1 1 1 PH domain DUF4407 PF14362.6 ORY19285.1 - 6.9 5.9 16.9 13 5.0 16.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Borrelia_P83 PF05262.11 ORY19285.1 - 9.5 4.6 19.6 16 3.8 19.6 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein Glycogen_syn PF05693.13 ORY19286.1 - 0 1144.8 0.0 0 1144.5 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.20 ORY19286.1 - 2.1e-05 24.2 0.0 0.012 15.2 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 ORY19286.1 - 0.0002 21.8 0.0 0.23 11.9 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 ORY19286.1 - 0.00074 19.6 0.1 0.0014 18.7 0.1 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_transf_5 PF08323.11 ORY19286.1 - 0.0048 16.6 0.0 0.013 15.2 0.0 1.8 2 0 0 2 2 2 1 Starch synthase catalytic domain Glyco_trans_4_4 PF13579.6 ORY19286.1 - 0.0056 17.1 0.0 0.012 16.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain DUF759 PF05537.11 ORY19286.1 - 0.02 13.8 0.5 0.035 13.0 0.5 1.3 1 0 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF759) TrkH PF02386.16 ORY19287.1 - 8.7e-148 492.9 2.4 8.7e-148 492.9 2.4 2.1 2 0 0 2 2 2 2 Cation transport protein AA_permease_2 PF13520.6 ORY19289.1 - 2.3e-85 287.0 39.3 2.9e-85 286.7 39.3 1.1 1 0 0 1 1 1 1 Amino acid permease PsbN PF02468.15 ORY19289.1 - 0.066 13.1 2.1 0.48 10.3 2.1 2.5 1 0 0 1 1 1 0 Photosystem II reaction centre N protein (psbN) Aminotran_1_2 PF00155.21 ORY19290.1 - 9.6e-11 41.4 0.0 1.1e-07 31.4 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class I and II LCCL PF03815.19 ORY19291.1 - 2.7e-21 75.5 0.1 4.7e-21 74.7 0.1 1.3 1 0 0 1 1 1 1 LCCL domain ATE_N PF04376.13 ORY19292.1 - 0.15 12.5 0.6 8.2 6.9 0.0 2.2 2 0 0 2 2 2 0 Arginine-tRNA-protein transferase, N terminus DUF1996 PF09362.10 ORY19293.1 - 7.5e-68 229.0 0.5 1.1e-67 228.5 0.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) AAA PF00004.29 ORY19295.1 - 4e-13 49.9 0.0 4.3e-11 43.3 0.0 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BCS1_N PF08740.11 ORY19295.1 - 2.1e-12 47.4 0.5 3.9e-12 46.5 0.3 1.6 2 0 0 2 2 2 1 BCS1 N terminal AAA_33 PF13671.6 ORY19295.1 - 0.0022 18.2 0.0 0.0043 17.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 ORY19295.1 - 0.022 14.8 0.0 0.037 14.0 0.0 1.4 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 ORY19295.1 - 0.025 15.0 0.1 0.042 14.2 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_11 PF13086.6 ORY19295.1 - 0.059 13.1 0.2 0.14 12.0 0.1 1.7 1 1 1 2 2 2 0 AAA domain AAA_18 PF13238.6 ORY19295.1 - 0.066 13.8 0.0 0.12 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 ORY19295.1 - 0.1 11.9 0.0 0.13 11.5 0.0 1.3 1 1 0 1 1 1 0 KaiC TIP49 PF06068.13 ORY19295.1 - 0.16 11.1 0.0 0.23 10.6 0.0 1.1 1 0 0 1 1 1 0 TIP49 P-loop domain RuvB_N PF05496.12 ORY19295.1 - 0.18 11.6 0.0 0.29 10.9 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 ORY19295.1 - 0.18 11.4 0.0 0.29 10.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Hydin_ADK PF17213.3 ORY19295.1 - 0.19 12.0 0.0 0.34 11.2 0.0 1.3 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Peptidase_S41 PF03572.18 ORY19297.1 - 2.4e-08 33.7 0.0 4.5e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase family S41 OTT_1508_deam PF14441.6 ORY19298.1 - 3.7e-18 65.3 1.4 3.7e-18 65.3 1.4 1.9 2 0 0 2 2 2 1 OTT_1508-like deaminase FSA_C PF10479.9 ORY19298.1 - 3.2 5.8 6.7 6.6 4.7 6.7 1.4 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus DIOX_N PF14226.6 ORY19299.1 - 1.2e-23 84.1 0.0 1.9e-23 83.5 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 ORY19299.1 - 8.2e-22 77.6 0.1 2.5e-21 76.1 0.0 1.8 2 1 1 3 3 3 1 2OG-Fe(II) oxygenase superfamily Questin_oxidase PF14027.6 ORY19300.1 - 9.8e-104 347.5 4.6 1.2e-103 347.3 4.6 1.1 1 0 0 1 1 1 1 Questin oxidase-like DUF3848 PF12959.7 ORY19300.1 - 0.063 13.3 0.1 0.21 11.7 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3848) SGS PF05002.15 ORY19301.1 - 3.2e-31 107.3 1.2 3.2e-31 107.3 1.2 2.3 2 0 0 2 2 2 1 SGS domain CS PF04969.16 ORY19301.1 - 2.5e-14 54.1 0.0 4.4e-14 53.3 0.0 1.4 1 0 0 1 1 1 1 CS domain TPR_2 PF07719.17 ORY19301.1 - 1.7e-06 27.7 4.5 0.034 14.3 0.3 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 ORY19301.1 - 1e-05 25.1 3.3 0.012 15.4 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat CCDC53 PF10152.9 ORY19301.1 - 0.0017 18.8 0.2 0.0017 18.8 0.2 2.2 2 0 0 2 2 2 1 Subunit CCDC53 of WASH complex TPR_9 PF13371.6 ORY19301.1 - 0.0042 17.2 1.0 0.0084 16.2 1.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 ORY19301.1 - 0.0098 16.6 4.0 0.26 12.2 0.1 3.5 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 ORY19301.1 - 0.052 14.2 11.4 0.45 11.2 0.6 2.9 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 ORY19301.1 - 0.081 12.6 1.9 0.21 11.3 0.7 2.3 1 1 1 2 2 2 0 TPR repeat TPR_19 PF14559.6 ORY19301.1 - 0.12 12.9 3.8 7.3 7.2 0.2 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 ORY19301.1 - 0.12 12.6 5.6 0.22 11.8 1.8 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat SNAPc19 PF15497.6 ORY19301.1 - 0.16 12.4 0.3 0.54 10.7 0.1 2.1 2 0 0 2 2 1 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 Aldo_ket_red PF00248.21 ORY19302.1 - 1.1e-56 192.2 0.0 1.2e-56 192.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family ApbA_C PF08546.11 ORY19302.1 - 0.16 12.2 0.0 8.5 6.6 0.0 2.7 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA C terminal ScsC_N PF18312.1 ORY19302.1 - 0.27 11.1 1.3 1.3 8.8 0.1 2.5 2 0 0 2 2 2 0 Copper resistance protein ScsC N-terminal domain PAF-AH_p_II PF03403.13 ORY19304.1 - 4.7e-20 71.5 0.0 1.9e-11 43.1 0.0 2.1 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Hydrolase_4 PF12146.8 ORY19304.1 - 1.1e-05 24.9 0.1 0.021 14.1 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 ORY19304.1 - 0.00064 19.3 0.4 0.0013 18.2 0.1 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 ORY19304.1 - 0.0034 17.1 0.0 0.23 11.1 0.0 2.3 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 ORY19304.1 - 0.019 14.6 0.1 0.042 13.4 0.1 1.5 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Chlorophyllase2 PF12740.7 ORY19304.1 - 0.068 12.1 0.0 0.57 9.1 0.0 2.0 1 1 0 1 1 1 0 Chlorophyllase enzyme GMC_oxred_N PF00732.19 ORY19305.1 - 6.5e-57 193.2 0.0 8.5e-57 192.8 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 ORY19305.1 - 2.6e-32 112.3 0.1 4.1e-32 111.7 0.1 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 ORY19305.1 - 2.4e-05 23.6 0.0 4e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 ORY19305.1 - 4.7e-05 23.5 0.0 0.00028 21.0 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 ORY19305.1 - 0.00073 18.8 0.0 0.0013 18.0 0.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 ORY19305.1 - 0.0013 17.9 0.1 0.0091 15.1 0.1 2.0 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 ORY19305.1 - 0.0022 17.3 0.1 0.0067 15.7 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ORY19305.1 - 0.0039 16.8 0.2 0.0098 15.5 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 ORY19305.1 - 0.0039 16.5 0.1 0.15 11.3 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ORY19305.1 - 0.0085 14.8 0.1 0.016 13.9 0.1 1.4 1 0 0 1 1 1 1 HI0933-like protein Period_C PF12114.8 ORY19306.1 - 0.012 15.2 4.1 0.019 14.5 4.1 1.2 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Dsh_C PF12316.8 ORY19306.1 - 0.52 10.7 14.0 0.57 10.6 13.5 1.3 1 1 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal CCDC106 PF15794.5 ORY19306.1 - 7.7 6.2 12.0 1 9.0 6.9 1.8 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 DnaJ PF00226.31 ORY19308.1 - 0.0052 16.9 0.0 0.0089 16.1 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain ANAPC8 PF04049.13 ORY19310.1 - 2.1e-51 173.6 0.0 4.6e-51 172.5 0.0 1.6 1 0 0 1 1 1 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_1 PF00515.28 ORY19310.1 - 5.9e-25 86.0 1.9 0.0007 19.3 0.0 7.4 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_8 PF13181.6 ORY19310.1 - 5.3e-18 63.7 3.8 0.00083 19.4 0.0 7.0 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_2 PF07719.17 ORY19310.1 - 1.2e-12 46.9 18.0 0.028 14.5 0.0 7.9 9 0 0 9 9 8 5 Tetratricopeptide repeat TPR_16 PF13432.6 ORY19310.1 - 1.8e-12 47.7 0.4 0.00012 22.6 0.0 5.7 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.6 ORY19310.1 - 6e-11 42.2 22.4 0.037 14.8 0.0 8.4 9 1 1 10 10 7 4 Tetratricopeptide repeat TPR_11 PF13414.6 ORY19310.1 - 1.5e-09 37.4 0.1 6e-06 25.9 0.0 4.5 4 1 1 5 5 5 1 TPR repeat ANAPC3 PF12895.7 ORY19310.1 - 6.7e-08 32.6 3.0 0.34 11.2 0.1 5.8 5 1 2 7 7 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 ORY19310.1 - 1.4e-06 28.7 0.8 0.18 12.3 0.0 5.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 ORY19310.1 - 2.5e-06 27.7 14.8 1.2 9.5 0.0 6.9 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 ORY19310.1 - 3.6e-06 27.0 1.3 3.3 8.3 0.0 7.1 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_6 PF13174.6 ORY19310.1 - 1.3e-05 25.5 17.0 0.13 12.9 0.5 7.0 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_9 PF13371.6 ORY19310.1 - 0.00052 20.1 4.7 10 6.4 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 ORY19310.1 - 0.0017 18.3 2.5 23 5.2 0.0 4.5 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_7 PF13176.6 ORY19310.1 - 0.0096 15.9 12.0 2.7 8.2 0.0 6.4 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_15 PF13429.6 ORY19310.1 - 0.026 13.7 9.7 0.034 13.4 0.8 4.3 3 1 1 5 5 5 0 Tetratricopeptide repeat Cnd1 PF12717.7 ORY19310.1 - 0.097 12.7 0.3 0.19 11.8 0.3 1.4 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 DUF3856 PF12968.7 ORY19310.1 - 0.2 11.7 1.0 2.7 8.1 0.1 3.0 2 1 1 3 3 3 0 Domain of Unknown Function (DUF3856) TPR_10 PF13374.6 ORY19310.1 - 4.3 7.3 8.8 69 3.5 0.0 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat polyprenyl_synt PF00348.17 ORY19311.1 - 2.5e-93 311.8 0.0 3.4e-93 311.4 0.0 1.2 1 0 0 1 1 1 1 Polyprenyl synthetase RNase_H2-Ydr279 PF09468.10 ORY19311.1 - 0.00057 20.1 0.5 0.0084 16.3 0.2 2.2 2 0 0 2 2 2 1 Ydr279p protein family (RNase H2 complex component) wHTH domain YkyB PF14177.6 ORY19311.1 - 0.11 12.8 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 YkyB-like protein adh_short PF00106.25 ORY19313.1 - 2.1e-36 125.2 0.1 2.7e-36 124.9 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY19313.1 - 3.4e-28 98.8 0.0 4.5e-28 98.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY19313.1 - 3.1e-12 46.8 0.0 5.4e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 KR domain PEP_hydrolase PF09370.10 ORY19313.1 - 0.0063 15.8 0.4 0.058 12.6 0.0 2.2 1 1 1 2 2 2 1 Phosphoenolpyruvate hydrolase-like Fungal_trans_2 PF11951.8 ORY19314.1 - 8.1e-08 31.5 1.6 0.00055 18.8 0.0 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Aldedh PF00171.22 ORY19315.1 - 2.3e-15 56.1 0.0 9.4e-10 37.6 0.0 2.7 2 1 1 3 3 3 2 Aldehyde dehydrogenase family GARS_C PF02843.16 ORY19315.1 - 0.12 12.7 0.1 0.27 11.6 0.1 1.5 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, C domain FAD_binding_3 PF01494.19 ORY19317.1 - 3e-23 82.6 0.1 8.3e-23 81.2 0.1 1.7 1 1 0 1 1 1 1 FAD binding domain ADC PF06314.11 ORY19317.1 - 5.9e-16 58.7 0.0 9.5e-16 58.1 0.0 1.2 1 0 0 1 1 1 1 Acetoacetate decarboxylase (ADC) Pyr_redox_2 PF07992.14 ORY19317.1 - 1.1e-10 41.3 1.0 4.9e-10 39.1 1.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ORY19317.1 - 1.2e-07 31.7 1.8 1.8e-06 27.8 0.5 2.3 1 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ORY19317.1 - 1.4e-07 31.6 0.2 3.1e-07 30.5 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 ORY19317.1 - 2.6e-06 26.8 0.2 4e-06 26.2 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 ORY19317.1 - 0.00044 20.7 0.4 0.0041 17.6 0.3 2.4 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 ORY19317.1 - 0.0013 18.2 0.1 0.002 17.5 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 ORY19317.1 - 0.0022 16.8 0.2 0.0043 15.8 0.2 1.4 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.22 ORY19317.1 - 0.0026 16.9 0.3 0.0046 16.1 0.3 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 ORY19317.1 - 0.004 16.5 0.6 0.13 11.5 0.2 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 ORY19317.1 - 0.013 14.8 0.0 0.031 13.6 0.0 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 ORY19317.1 - 0.014 14.7 0.0 0.027 13.7 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.14 ORY19317.1 - 0.017 14.0 0.1 0.033 13.0 0.1 1.4 1 0 0 1 1 1 0 Tryptophan halogenase MCRA PF06100.11 ORY19317.1 - 0.021 13.7 0.1 0.031 13.1 0.1 1.2 1 0 0 1 1 1 0 MCRA family Lycopene_cycl PF05834.12 ORY19317.1 - 0.056 12.5 0.1 2.9 6.8 0.1 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein ApbA PF02558.16 ORY19317.1 - 0.13 11.9 0.3 0.23 11.1 0.3 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA MFS_1 PF07690.16 ORY19318.1 - 3.9e-29 101.7 24.7 3.9e-29 101.7 24.7 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY19318.1 - 2.5e-10 39.8 1.9 2.5e-10 39.8 1.9 3.3 4 0 0 4 4 4 1 Sugar (and other) transporter Fungal_trans PF04082.18 ORY19318.1 - 6.2e-07 28.7 0.1 1.2e-06 27.8 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain TRI12 PF06609.13 ORY19318.1 - 5.5e-05 21.8 3.6 0.00011 20.8 3.6 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) CPP1-like PF11833.8 ORY19318.1 - 2.4 7.8 4.0 6.8 6.3 4.0 1.7 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like LigB PF02900.18 ORY19319.1 - 6.8e-12 45.0 0.0 8.9e-12 44.6 0.0 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase PepX_C PF08530.10 ORY19320.1 - 1.2e-42 146.4 0.1 1.8e-42 145.8 0.1 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Peptidase_S15 PF02129.18 ORY19320.1 - 1e-39 136.8 0.3 1.5e-39 136.2 0.3 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.8 ORY19320.1 - 0.047 12.9 0.0 0.066 12.5 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Cupin_2 PF07883.11 ORY19321.1 - 2.6e-08 33.5 0.1 3.9e-08 32.9 0.1 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 ORY19321.1 - 0.1 12.3 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF861) zf-RING_2 PF13639.6 ORY19322.1 - 3.1e-05 24.2 10.3 7.8e-05 22.9 10.3 1.8 1 0 0 1 1 1 1 Ring finger domain zf-RING_4 PF14570.6 ORY19322.1 - 0.036 13.8 6.9 0.079 12.8 6.9 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF1272 PF06906.11 ORY19322.1 - 0.48 10.6 6.0 1.4 9.0 6.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-RING_UBOX PF13445.6 ORY19322.1 - 0.66 10.1 5.7 0.7 10.0 4.3 1.9 1 1 0 1 1 1 0 RING-type zinc-finger zf-rbx1 PF12678.7 ORY19322.1 - 3.2 8.1 8.2 8.6 6.7 8.2 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain FTA2 PF13095.6 ORY19325.1 - 0.22 11.1 0.1 0.31 10.6 0.1 1.2 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Glyco_hydro_31 PF01055.26 ORY19326.1 - 1.3e-139 466.2 6.7 1.8e-139 465.8 6.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 ORY19326.1 - 1.2e-25 89.6 1.1 4.4e-25 87.8 0.3 2.4 2 0 0 2 2 2 1 Galactose mutarotase-like DUF5110 PF17137.4 ORY19326.1 - 7.1e-08 32.6 0.2 1.8e-07 31.3 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) FinO_N PF12602.8 ORY19326.1 - 0.25 11.7 4.3 0.6 10.5 4.3 1.6 1 0 0 1 1 1 0 Fertility inhibition protein N terminal NDK PF00334.19 ORY19327.1 - 3.9e-54 182.3 0.0 5e-54 182.0 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Helo_like_N PF17111.5 ORY19330.1 - 3.6e-11 42.8 0.4 9.2e-11 41.5 0.4 1.7 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins NACHT PF05729.12 ORY19330.1 - 3e-10 40.3 0.0 7.1e-10 39.0 0.0 1.6 1 0 0 1 1 1 1 NACHT domain SesA PF17107.5 ORY19330.1 - 3.1e-06 27.4 0.5 1.1e-05 25.6 0.5 2.0 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases AAA_16 PF13191.6 ORY19330.1 - 8.4e-05 23.0 0.3 0.00038 20.9 0.1 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 ORY19330.1 - 0.00038 20.7 0.0 0.0018 18.6 0.0 2.1 1 1 1 2 2 2 1 AAA domain DUF2383 PF09537.10 ORY19330.1 - 0.0051 17.1 0.0 0.035 14.4 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF2383) ApoC-I PF04691.12 ORY19330.1 - 0.013 15.4 0.1 0.79 9.7 0.0 2.8 2 0 0 2 2 2 0 Apolipoprotein C-I (ApoC-1) AAA_13 PF13166.6 ORY19330.1 - 0.066 11.8 2.6 0.13 10.9 2.6 1.4 1 0 0 1 1 1 0 AAA domain Ank_2 PF12796.7 ORY19330.1 - 0.073 13.7 0.0 0.24 12.0 0.0 1.9 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) NB-ARC PF00931.22 ORY19330.1 - 0.16 11.1 0.0 0.43 9.7 0.0 1.7 1 1 0 1 1 1 0 NB-ARC domain GAS PF13851.6 ORY19330.1 - 0.16 11.3 3.1 2.9 7.2 4.0 2.4 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding DASH_Duo1 PF08651.10 ORY19330.1 - 0.29 10.9 1.1 7.5 6.4 0.1 3.3 3 1 0 3 3 3 0 DASH complex subunit Duo1 Prefoldin PF02996.17 ORY19330.1 - 0.49 10.3 3.9 16 5.4 0.1 2.9 3 0 0 3 3 2 0 Prefoldin subunit ABC_tran_CTD PF16326.5 ORY19330.1 - 0.86 9.9 3.7 1.1 9.6 0.6 2.8 2 1 0 2 2 2 0 ABC transporter C-terminal domain Apolipoprotein PF01442.18 ORY19330.1 - 0.93 9.3 4.2 0.65 9.8 1.1 2.2 3 0 0 3 3 2 0 Apolipoprotein A1/A4/E domain GrpE PF01025.19 ORY19330.1 - 3.7 7.2 5.0 3.5 7.3 2.7 2.2 3 0 0 3 3 3 0 GrpE CorA PF01544.18 ORY19330.1 - 6.8 5.9 7.5 2.4 7.4 4.0 2.0 2 1 0 2 2 2 0 CorA-like Mg2+ transporter protein Ank_4 PF13637.6 ORY19331.1 - 1.5e-12 47.8 0.1 2.2e-06 28.1 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 ORY19331.1 - 2.7e-10 40.2 4.4 0.00031 21.0 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 ORY19331.1 - 1.4e-09 38.4 1.0 5.2e-09 36.6 1.0 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ORY19331.1 - 5.5e-09 35.5 0.9 0.018 15.6 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 ORY19331.1 - 0.001 19.3 0.1 0.093 13.1 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) NuA4 PF09340.10 ORY19371.1 - 1.4e-27 95.3 0.1 2.3e-27 94.7 0.1 1.3 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 Hamartin PF04388.12 ORY19371.1 - 0.43 9.2 3.6 0.45 9.1 3.6 1.1 1 0 0 1 1 1 0 Hamartin protein TFIIS_M PF07500.14 ORY19372.1 - 8.2e-33 113.2 1.7 1.9e-32 112.1 1.7 1.6 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 ORY19372.1 - 5e-17 61.5 8.9 8.2e-17 60.8 8.9 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 ORY19372.1 - 6.9e-13 48.4 0.6 1.9e-12 47.0 0.6 1.8 1 0 0 1 1 1 1 TFIIS helical bundle-like domain DUF2202 PF09968.9 ORY19372.1 - 0.07 13.0 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein domain (DUF2202) Evr1_Alr PF04777.13 ORY19372.1 - 0.072 13.6 1.1 0.19 12.2 1.1 1.7 1 0 0 1 1 1 0 Erv1 / Alr family CcmH PF03918.14 ORY19372.1 - 3.2 7.1 5.9 1.3 8.3 2.5 2.0 2 0 0 2 2 2 0 Cytochrome C biogenesis protein WD40 PF00400.32 ORY19373.1 - 5.5e-51 169.4 29.9 3.8e-06 27.5 0.3 12.1 12 0 0 12 12 12 10 WD domain, G-beta repeat Utp12 PF04003.12 ORY19373.1 - 5.5e-21 74.9 0.0 1.1e-20 73.9 0.0 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 ORY19373.1 - 3.3e-19 69.0 9.8 0.00022 21.5 0.0 10.1 5 3 5 10 10 10 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 ORY19373.1 - 8.6e-09 34.8 5.5 0.25 10.2 0.0 6.6 3 2 4 7 7 7 4 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 ORY19373.1 - 3e-06 26.2 7.6 0.19 10.4 0.1 6.0 5 2 0 5 5 5 2 Nucleoporin Nup120/160 eIF2A PF08662.11 ORY19373.1 - 7.2e-05 22.8 0.5 0.041 13.8 0.0 4.6 5 1 1 6 6 6 1 Eukaryotic translation initiation factor eIF2A Utp21 PF04192.12 ORY19373.1 - 0.001 18.6 0.1 0.0016 18.0 0.1 1.4 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain PQQ_2 PF13360.6 ORY19373.1 - 0.0053 16.4 7.9 0.031 13.9 1.5 2.8 2 0 0 2 2 2 2 PQQ-like domain WD40_like PF17005.5 ORY19373.1 - 0.0062 15.9 0.1 23 4.2 0.0 4.2 4 1 0 4 4 4 0 WD40-like domain Nucleoporin_N PF08801.11 ORY19373.1 - 0.031 13.0 0.8 2.1 7.0 0.0 3.9 3 1 1 4 4 4 0 Nup133 N terminal like Nbas_N PF15492.6 ORY19373.1 - 0.15 11.4 0.7 8.9 5.5 0.0 3.3 2 1 2 4 4 4 0 Neuroblastoma-amplified sequence, N terminal RRP36 PF06102.12 ORY19373.1 - 9.4 6.2 7.9 11 5.9 1.8 2.4 2 0 0 2 2 2 0 rRNA biogenesis protein RRP36 P34-Arc PF04045.14 ORY19374.1 - 2.5e-107 358.1 1.0 3e-107 357.8 1.0 1.1 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc ARPC4 PF05856.12 ORY19374.1 - 0.0022 17.6 0.3 0.0039 16.8 0.3 1.4 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) Radical_SAM PF04055.21 ORY19374.1 - 0.051 13.9 0.4 1 9.7 0.3 2.5 1 1 2 3 3 3 0 Radical SAM superfamily Dynamitin PF04912.14 ORY19375.1 - 7.3e-82 275.7 4.0 8.6e-82 275.5 4.0 1.1 1 0 0 1 1 1 1 Dynamitin HET PF06985.11 ORY19379.1 - 1.6e-05 25.3 0.3 2.9e-05 24.5 0.3 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) p450 PF00067.22 ORY19380.1 - 0.017 13.9 0.0 0.02 13.7 0.0 1.0 1 0 0 1 1 1 0 Cytochrome P450 zf-B_box PF00643.24 ORY19381.1 - 0.017 15.3 1.7 0.026 14.7 1.7 1.2 1 0 0 1 1 1 0 B-box zinc finger CEBP_ZZ PF16366.5 ORY19381.1 - 0.49 10.7 2.5 0.96 9.7 2.5 1.5 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain Metallophos PF00149.28 ORY19382.1 - 9.3e-09 36.1 2.0 2.5e-08 34.7 2.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase DUF4702 PF15774.5 ORY19382.1 - 0.015 14.3 0.2 0.027 13.5 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4702) FAD_binding_2 PF00890.24 ORY19383.1 - 3.1e-61 207.7 0.1 4.3e-61 207.3 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.28 ORY19383.1 - 4.3e-20 71.6 0.2 9e-19 67.4 0.0 2.9 4 0 0 4 4 4 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.24 ORY19383.1 - 0.005 16.5 0.0 0.01 15.5 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 ORY19383.1 - 0.011 15.0 0.0 0.018 14.3 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Ctr PF04145.15 ORY19384.1 - 2.4e-35 122.3 1.0 2.9e-35 122.1 1.0 1.0 1 0 0 1 1 1 1 Ctr copper transporter family MTABC_N PF16185.5 ORY19384.1 - 0.045 13.3 0.2 0.1 12.1 0.1 1.6 2 0 0 2 2 2 0 Mitochondrial ABC-transporter N-terminal five TM region 3-HAO PF06052.12 ORY19385.1 - 6.6e-67 223.9 0.1 8.2e-67 223.5 0.1 1.1 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.11 ORY19385.1 - 1.3e-05 24.8 0.0 2.1e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 ORY19385.1 - 0.00012 22.0 0.0 0.0002 21.3 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.22 ORY19385.1 - 0.0028 17.3 0.0 0.0043 16.7 0.0 1.3 1 0 0 1 1 1 1 Cupin DZR PF12773.7 ORY19385.1 - 0.01 15.9 5.4 0.01 15.9 5.4 1.7 2 0 0 2 2 2 0 Double zinc ribbon DUF2321 PF10083.9 ORY19385.1 - 0.1 12.2 1.3 0.17 11.5 1.3 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) HypA PF01155.19 ORY19385.1 - 0.1 12.6 0.7 0.27 11.3 0.7 1.7 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn-ribbon_8 PF09723.10 ORY19385.1 - 0.37 11.0 5.5 17 5.6 5.6 2.4 1 1 1 2 2 2 0 Zinc ribbon domain zf-ribbon_3 PF13248.6 ORY19385.1 - 0.48 9.9 0.1 0.48 9.9 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain C1_1 PF00130.22 ORY19385.1 - 1.6 8.7 8.1 1.5 8.7 1.6 2.4 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zinc_ribbon_2 PF13240.6 ORY19385.1 - 1.9 8.3 8.6 6.7 6.6 0.2 3.2 4 0 0 4 4 4 0 zinc-ribbon domain ORC3_N PF07034.11 ORY19386.1 - 2.8e-39 135.2 0.0 3.3e-38 131.6 0.0 2.2 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus ORC_WH_C PF18137.1 ORY19386.1 - 1.1e-28 100.0 0.1 7e-17 61.8 0.0 2.5 1 1 1 2 2 2 2 Origin recognition complex winged helix C-terminal SLT_2 PF13406.6 ORY19386.1 - 0.041 13.1 0.0 0.076 12.2 0.0 1.4 1 0 0 1 1 1 0 Transglycosylase SLT domain DUF4187 PF13821.6 ORY19387.1 - 8.1e-22 76.8 1.1 8.1e-22 76.8 1.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4187) G-patch PF01585.23 ORY19387.1 - 5.5e-14 51.8 0.1 1e-13 50.9 0.1 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 ORY19387.1 - 0.076 13.1 0.2 0.076 13.1 0.2 2.9 4 0 0 4 4 4 0 G-patch domain DUF3712 PF12505.8 ORY19389.1 - 1.1e-34 119.4 4.5 1.1e-34 119.3 2.7 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3712) LEA_2 PF03168.13 ORY19389.1 - 0.073 13.6 0.3 3.4 8.3 0.1 2.5 2 0 0 2 2 2 0 Late embryogenesis abundant protein Sec63 PF02889.16 ORY19390.1 - 4.3e-164 543.8 0.2 6e-91 304.2 0.0 2.5 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 ORY19390.1 - 1.6e-44 151.7 0.0 7e-27 94.3 0.0 3.1 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_PWI PF18149.1 ORY19390.1 - 2.1e-33 114.8 2.6 2.1e-33 114.8 2.6 2.3 2 0 0 2 2 2 1 N-terminal helicase PWI domain ResIII PF04851.15 ORY19390.1 - 1.3e-20 74.2 0.0 2.5e-13 50.4 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 ORY19390.1 - 2e-10 41.0 0.0 3.5e-08 33.8 0.0 3.7 2 1 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 ORY19390.1 - 0.00016 22.0 0.1 0.026 14.8 0.0 3.0 2 1 0 2 2 2 1 AAA domain PhoH PF02562.16 ORY19390.1 - 0.002 17.6 0.0 0.21 11.0 0.0 2.8 3 0 0 3 3 3 1 PhoH-like protein UvrD-helicase PF00580.21 ORY19390.1 - 0.008 15.7 0.2 3.5 7.1 0.0 3.4 3 0 0 3 3 3 1 UvrD/REP helicase N-terminal domain CAP_GLY PF01302.25 ORY19391.1 - 2.7e-16 59.3 1.9 7.5e-16 57.9 1.9 1.8 1 0 0 1 1 1 1 CAP-Gly domain NPV_P10 PF05531.12 ORY19391.1 - 2.2e-06 28.0 4.1 0.014 15.8 0.3 3.0 3 0 0 3 3 2 2 Nucleopolyhedrovirus P10 protein CLIP1_ZNF PF16641.5 ORY19391.1 - 6e-05 22.8 3.1 6e-05 22.8 3.1 3.0 3 0 0 3 3 3 1 CLIP1 zinc knuckle Spc7 PF08317.11 ORY19391.1 - 0.00021 20.3 24.6 0.027 13.4 9.8 3.2 3 0 0 3 3 3 3 Spc7 kinetochore protein AAA_13 PF13166.6 ORY19391.1 - 0.00035 19.4 0.5 0.00035 19.4 0.5 2.5 2 1 0 3 3 3 1 AAA domain DUF812 PF05667.11 ORY19391.1 - 0.00059 18.9 12.2 0.00059 18.9 12.2 2.2 1 1 0 2 2 2 1 Protein of unknown function (DUF812) Phage_GP20 PF06810.11 ORY19391.1 - 0.0016 18.2 14.0 0.088 12.6 1.4 3.8 4 0 0 4 4 4 2 Phage minor structural protein GP20 FAM76 PF16046.5 ORY19391.1 - 0.003 17.0 6.9 0.3 10.4 0.0 3.0 3 0 0 3 3 3 2 FAM76 protein ATG16 PF08614.11 ORY19391.1 - 0.0094 16.2 28.3 0.1 12.8 0.1 4.3 3 1 0 3 3 3 1 Autophagy protein 16 (ATG16) Laminin_II PF06009.12 ORY19391.1 - 0.046 13.7 9.3 0.32 11.0 0.6 3.3 3 0 0 3 3 3 0 Laminin Domain II Glutaredoxin2_C PF04399.13 ORY19391.1 - 0.083 12.7 1.0 7.3 6.4 0.0 2.4 2 0 0 2 2 2 0 Glutaredoxin 2, C terminal domain Fez1 PF06818.15 ORY19391.1 - 0.16 12.4 30.1 0.2 12.1 11.9 3.1 2 1 1 3 3 3 0 Fez1 E2R135 PF11570.8 ORY19391.1 - 0.18 12.1 2.3 0.99 9.7 0.1 2.8 2 1 1 3 3 3 0 Coiled-coil receptor-binding R-domain of colicin E2 PI3K_P85_iSH2 PF16454.5 ORY19391.1 - 0.19 11.3 14.9 1.5 8.4 1.1 3.5 3 1 0 3 3 3 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain BLOC1_2 PF10046.9 ORY19391.1 - 0.23 11.8 13.4 0.056 13.7 2.6 3.3 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 HemX PF04375.14 ORY19391.1 - 0.24 10.7 13.1 0.08 12.2 2.2 3.1 3 0 0 3 3 3 0 HemX, putative uroporphyrinogen-III C-methyltransferase SKA1 PF07160.12 ORY19391.1 - 0.26 11.1 7.0 1.8 8.4 0.4 2.9 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 1 DUF4618 PF15397.6 ORY19391.1 - 0.3 10.5 12.4 0.71 9.2 0.3 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4618) DUF3450 PF11932.8 ORY19391.1 - 0.36 10.1 22.8 1.2 8.4 5.6 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3450) AAA_23 PF13476.6 ORY19391.1 - 0.41 11.1 8.2 0.51 10.8 2.2 2.3 2 0 0 2 2 2 0 AAA domain Baculo_PEP_C PF04513.12 ORY19391.1 - 0.53 10.3 2.2 2.7 8.0 0.3 2.3 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF241 PF03087.14 ORY19391.1 - 0.7 9.7 11.5 0.17 11.7 6.2 2.4 2 1 0 2 2 2 0 Arabidopsis protein of unknown function CENP-H PF05837.12 ORY19391.1 - 0.8 10.1 22.4 0.086 13.3 4.1 3.5 3 1 0 3 3 3 0 Centromere protein H (CENP-H) DUF1664 PF07889.12 ORY19391.1 - 0.82 9.7 12.6 0.2 11.7 2.3 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) FliD_N PF02465.18 ORY19391.1 - 0.82 10.4 2.7 47 4.8 0.1 2.9 3 0 0 3 3 3 0 Flagellar hook-associated protein 2 N-terminus BST2 PF16716.5 ORY19391.1 - 2.3 8.9 18.2 21 5.8 0.5 4.4 3 1 1 4 4 4 0 Bone marrow stromal antigen 2 Fmp27_WPPW PF10359.9 ORY19391.1 - 2.3 7.0 14.7 0.75 8.6 2.9 2.8 2 1 1 3 3 3 0 RNA pol II promoter Fmp27 protein domain DUF745 PF05335.13 ORY19391.1 - 2.5 7.8 18.1 0.53 10.0 1.6 3.7 3 1 1 4 4 4 0 Protein of unknown function (DUF745) HrpB7 PF09486.10 ORY19391.1 - 3.6 8.0 31.5 4.4 7.7 0.3 3.6 2 1 2 4 4 4 0 Bacterial type III secretion protein (HrpB7) DHR10 PF18595.1 ORY19391.1 - 3.6 7.7 36.3 0.1 12.7 11.1 3.5 3 0 0 3 3 3 0 Designed helical repeat protein 10 domain TPR_MLP1_2 PF07926.12 ORY19391.1 - 6.6 6.8 32.2 0.51 10.4 12.4 4.1 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein DUF4201 PF13870.6 ORY19391.1 - 8.5 6.1 19.3 3.5 7.3 4.2 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4201) Sec8_exocyst PF04048.14 ORY19391.1 - 9 6.2 10.0 0.75 9.7 0.5 3.0 3 1 0 3 3 3 0 Sec8 exocyst complex component specific domain APH PF01636.23 ORY19392.1 - 1.6e-39 136.3 0.0 3.4e-39 135.2 0.0 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.20 ORY19392.1 - 7.9e-06 25.4 0.0 1.3e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.20 ORY19392.1 - 0.00015 21.4 0.0 0.00026 20.7 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 ORY19392.1 - 0.0046 16.6 0.1 0.075 12.6 0.0 2.4 2 1 0 2 2 2 1 RIO1 family Fructosamin_kin PF03881.14 ORY19392.1 - 0.0098 15.1 0.0 0.14 11.3 0.0 2.2 1 1 0 1 1 1 1 Fructosamine kinase Kdo PF06293.14 ORY19392.1 - 0.023 14.1 0.0 0.12 11.7 0.0 2.0 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1679 PF07914.11 ORY19392.1 - 0.028 13.3 0.0 0.093 11.6 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1679) LSM PF01423.22 ORY19393.1 - 2.6e-20 71.8 0.9 3e-20 71.7 0.9 1.0 1 0 0 1 1 1 1 LSM domain Cas_NE0113 PF09623.10 ORY19393.1 - 0.097 12.4 0.0 0.12 12.1 0.0 1.1 1 0 0 1 1 1 0 CRISPR-associated protein NE0113 (Cas_NE0113) RasGAP_C PF03836.15 ORY19394.1 - 0.0007 19.7 1.2 0.0079 16.3 0.1 2.7 2 1 0 3 3 3 1 RasGAP C-terminus THP2 PF09432.10 ORY19394.1 - 0.01 15.9 0.2 0.021 14.8 0.2 1.5 1 0 0 1 1 1 0 Tho complex subunit THP2 BAR PF03114.18 ORY19394.1 - 0.065 12.9 9.1 0.1 12.2 9.1 1.2 1 0 0 1 1 1 0 BAR domain DUF2972 PF11186.8 ORY19394.1 - 0.13 12.2 0.2 0.21 11.5 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2972) Cmc1 PF08583.10 ORY19395.1 - 3.1e-19 68.8 5.1 3.6e-19 68.6 5.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like NDUF_B7 PF05676.13 ORY19395.1 - 0.0033 17.1 1.1 0.0046 16.7 1.1 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) UPF0203 PF05254.12 ORY19395.1 - 0.01 16.1 4.1 0.25 11.6 1.8 2.6 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) RPN7 PF10602.9 ORY19395.1 - 0.013 15.2 0.1 0.013 15.2 0.1 1.2 1 0 0 1 1 1 0 26S proteasome subunit RPN7 LPD30 PF18850.1 ORY19395.1 - 0.023 14.4 0.4 0.028 14.2 0.4 1.1 1 0 0 1 1 1 0 Large polyvalent protein associated domain 30 DUF728 PF05304.12 ORY19395.1 - 0.031 14.1 1.7 0.036 13.9 1.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF728) COX17 PF05051.13 ORY19395.1 - 0.087 13.2 1.7 5.7 7.4 0.1 2.2 2 0 0 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) MobC PF05713.11 ORY19395.1 - 0.1 13.1 1.3 5.6 7.5 0.0 2.4 2 0 0 2 2 2 0 Bacterial mobilisation protein (MobC) UCR_hinge PF02320.16 ORY19395.1 - 0.25 11.6 6.7 0.58 10.4 0.2 2.5 2 1 1 3 3 3 0 Ubiquinol-cytochrome C reductase hinge protein DUF3128 PF11326.8 ORY19395.1 - 0.93 9.9 5.6 1.8 9.0 5.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) Prefoldin_2 PF01920.20 ORY19396.1 - 8e-26 90.1 8.8 9.4e-26 89.8 8.8 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.17 ORY19396.1 - 0.02 14.8 7.4 0.68 9.9 7.4 2.2 1 1 0 1 1 1 0 Prefoldin subunit V_ATPase_I PF01496.19 ORY19396.1 - 0.1 10.5 2.1 0.12 10.3 2.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2089 PF09862.9 ORY19396.1 - 0.1 12.6 2.4 2.8 8.0 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2089) p25-alpha PF05517.12 ORY19396.1 - 0.19 11.9 3.6 1.7 8.8 0.6 2.0 2 0 0 2 2 2 0 p25-alpha Com_YlbF PF06133.11 ORY19396.1 - 0.4 11.3 8.4 1.5 9.5 0.3 2.1 2 0 0 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA DUF2205 PF10224.9 ORY19396.1 - 1.7 8.7 6.7 0.77 9.8 0.7 2.1 2 0 0 2 2 2 0 Short coiled-coil protein CBFD_NFYB_HMF PF00808.23 ORY19398.1 - 2.9e-25 88.3 1.8 2.9e-25 88.3 1.8 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 ORY19398.1 - 2.1e-07 31.3 0.1 3.5e-07 30.6 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.16 ORY19398.1 - 0.00099 19.1 0.0 0.0016 18.4 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.13 ORY19398.1 - 0.0022 18.0 0.1 0.0036 17.3 0.1 1.3 1 0 0 1 1 1 1 Bromodomain associated CENP-T_C PF15511.6 ORY19398.1 - 0.022 14.9 0.0 0.033 14.3 0.0 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold TFIID_20kDa PF03847.13 ORY19398.1 - 0.08 13.5 0.1 0.13 12.7 0.1 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A DHHC PF01529.20 ORY19399.1 - 7.7e-34 116.7 5.6 1.3e-33 115.9 5.6 1.4 1 0 0 1 1 1 1 DHHC palmitoyltransferase Transglut_core3 PF13471.6 ORY19399.1 - 0.11 12.4 0.4 0.22 11.4 0.4 1.4 1 0 0 1 1 1 0 Transglutaminase-like superfamily Glyco_transf_22 PF03901.17 ORY19400.1 - 1.2e-35 123.6 19.9 1.5e-35 123.2 19.9 1.2 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family UPF0060 PF02694.15 ORY19400.1 - 1.2 9.4 8.3 0.23 11.7 1.2 2.6 2 0 0 2 2 2 0 Uncharacterised BCR, YnfA/UPF0060 family SUI1 PF01253.22 ORY19401.1 - 3.6e-25 88.3 0.0 9.1e-25 87.0 0.0 1.7 1 0 0 1 1 1 1 Translation initiation factor SUI1 DUF3584 PF12128.8 ORY19401.1 - 0.0061 14.2 0.2 0.0072 13.9 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) PepSY_like PF11396.8 ORY19401.1 - 0.16 12.6 1.6 2.4 8.8 0.2 2.5 1 1 2 3 3 3 0 Putative beta-lactamase-inhibitor-like, PepSY-like TAP_C PF03943.13 ORY19402.1 - 3.3e-15 55.5 0.1 6.2e-15 54.6 0.1 1.5 1 0 0 1 1 1 1 TAP C-terminal domain NTF2 PF02136.20 ORY19402.1 - 0.0073 16.9 0.1 0.018 15.6 0.1 1.8 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain UBA_4 PF14555.6 ORY19402.1 - 0.062 13.1 0.2 0.19 11.6 0.0 1.9 2 0 0 2 2 2 0 UBA-like domain NUDIX PF00293.28 ORY19403.1 - 3.6e-08 33.5 0.0 9.8e-08 32.1 0.0 1.7 2 0 0 2 2 2 1 NUDIX domain Gly-zipper_OmpA PF13436.6 ORY19404.1 - 0.029 14.2 3.0 0.029 14.2 3.0 2.4 3 0 0 3 3 3 0 Glycine-zipper domain Carb_kinase PF01256.17 ORY19405.1 - 3.3e-57 193.8 0.1 4.1e-57 193.4 0.1 1.1 1 0 0 1 1 1 1 Carbohydrate kinase HK PF02110.15 ORY19405.1 - 1.1e-05 25.0 0.0 1.7e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family Phos_pyr_kin PF08543.12 ORY19405.1 - 0.017 14.5 0.0 0.037 13.4 0.0 1.6 1 1 0 1 1 1 0 Phosphomethylpyrimidine kinase PfkB PF00294.24 ORY19405.1 - 0.051 12.9 0.0 0.066 12.5 0.0 1.4 1 0 0 1 1 1 0 pfkB family carbohydrate kinase DPPIV_N PF00930.21 ORY19406.1 - 1.5e-111 372.6 0.2 2e-111 372.2 0.2 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 ORY19406.1 - 7.2e-56 189.0 0.8 1.3e-55 188.2 0.8 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 ORY19406.1 - 4.7e-08 32.9 0.6 4.2e-07 29.8 0.4 2.1 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.20 ORY19406.1 - 0.00018 21.2 0.1 0.00039 20.2 0.1 1.6 1 1 1 2 2 2 1 alpha/beta hydrolase fold Esterase PF00756.20 ORY19406.1 - 0.018 14.7 0.1 0.072 12.7 0.1 1.9 1 1 0 1 1 1 0 Putative esterase PAF-AH_p_II PF03403.13 ORY19406.1 - 0.032 12.8 0.0 0.11 11.0 0.0 1.8 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II DUF4911 PF16256.5 ORY19406.1 - 0.11 12.5 0.1 0.82 9.7 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4911) SHS2_Rpb7-N PF03876.17 ORY19407.1 - 1.2e-11 44.9 0.0 1.8e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 ORY19407.1 - 5e-10 39.6 0.0 9e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 S1 RNA binding domain RNA_pol_Rbc25 PF08292.12 ORY19407.1 - 0.00063 20.0 0.0 0.0011 19.2 0.0 1.4 1 1 0 1 1 1 1 RNA polymerase III subunit Rpc25 DUF962 PF06127.11 ORY19409.1 - 1.2e-25 89.5 0.0 1.9e-25 88.8 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF962) ATP-synt_ab PF00006.25 ORY19411.1 - 4.5e-73 245.4 0.0 6.6e-73 244.9 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 ORY19411.1 - 1.6e-46 157.8 0.1 2.6e-46 157.0 0.1 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 ORY19411.1 - 3.4e-15 56.3 2.9 9e-15 55.0 2.9 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain RbcS PF12338.8 ORY19411.1 - 3.2 8.0 6.2 1.7 8.9 0.2 3.1 3 0 0 3 3 3 0 Ribulose-1,5-bisphosphate carboxylase small subunit PKcGMP_CC PF16808.5 ORY19412.1 - 0.015 15.1 0.0 0.067 13.1 0.0 2.1 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase FlaC_arch PF05377.11 ORY19412.1 - 0.1 13.0 0.6 13 6.3 0.0 2.9 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) BLOC1_2 PF10046.9 ORY19412.1 - 0.19 12.0 0.9 0.71 10.2 0.3 2.0 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SlyX PF04102.12 ORY19412.1 - 1.7 9.3 9.8 6.4 7.5 2.8 3.3 2 1 1 3 3 3 0 SlyX SPT2 PF08243.11 ORY19413.1 - 3.1e-05 24.5 21.7 5.8e-05 23.6 21.7 1.4 1 0 0 1 1 1 1 SPT2 chromatin protein Ribosomal_60s PF00428.19 ORY19414.1 - 3.5e-26 91.6 9.7 4.1e-26 91.4 9.7 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein EF-hand_14 PF17959.1 ORY19414.1 - 0.011 16.1 0.5 0.014 15.7 0.0 1.4 2 0 0 2 2 2 0 EF-hand domain UBA_6 PF18039.1 ORY19414.1 - 0.017 15.0 0.5 0.035 14.0 0.1 1.7 2 0 0 2 2 2 0 UBA-like domain RibD_C PF01872.17 ORY19414.1 - 0.12 12.1 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 RibD C-terminal domain Cytomega_UL84 PF06284.11 ORY19414.1 - 0.18 10.3 1.2 0.21 10.0 1.2 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein DUF3824 PF12868.7 ORY19414.1 - 0.2 12.3 2.0 0.26 11.9 2.0 1.1 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) Ribosomal_S19 PF00203.21 ORY19415.1 - 1.8e-33 114.3 0.3 2.5e-33 113.8 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 Sec10 PF07393.11 ORY19416.1 - 3.7e-208 693.4 0.0 4.5e-208 693.1 0.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 Apolipoprotein PF01442.18 ORY19416.1 - 1.4 8.8 10.3 2.2 8.1 3.9 3.1 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain Mod_r PF07200.13 ORY19416.1 - 2.6 8.1 8.4 9.8 6.3 0.4 3.6 3 2 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein Exonuc_VII_L PF02601.15 ORY19416.1 - 3.6 7.0 6.1 4.4 6.8 0.1 2.6 2 1 0 2 2 2 0 Exonuclease VII, large subunit Baculo_PEP_C PF04513.12 ORY19416.1 - 4.7 7.2 12.5 0.36 10.9 0.1 3.6 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF5099 PF17025.5 ORY19417.1 - 0.0018 18.7 0.0 0.0028 18.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5099) Prenyltransf PF01255.19 ORY19417.1 - 0.016 14.7 0.0 0.052 13.1 0.0 1.7 2 0 0 2 2 2 0 Putative undecaprenyl diphosphate synthase SNF2_N PF00176.23 ORY19418.1 - 2.7e-60 203.9 0.0 8.4e-60 202.3 0.0 1.8 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ORY19418.1 - 7.9e-15 55.2 0.0 3.6e-14 53.0 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY19418.1 - 1.2e-07 31.9 0.0 2.5e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-RING_5 PF14634.6 ORY19418.1 - 0.77 9.8 12.7 2 8.5 12.7 1.8 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.25 ORY19418.1 - 3.8 7.5 13.3 10 6.1 13.3 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Ank_2 PF12796.7 ORY19419.1 - 9.4e-18 64.6 0.0 6.2e-10 39.5 0.0 4.5 2 2 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ORY19419.1 - 1.6e-12 46.4 0.3 0.17 12.5 0.0 7.2 7 0 0 7 7 7 3 Ankyrin repeat NACHT PF05729.12 ORY19419.1 - 2.7e-12 46.9 0.0 1.3e-11 44.7 0.0 2.2 2 0 0 2 2 2 1 NACHT domain Ank_4 PF13637.6 ORY19419.1 - 3.6e-11 43.3 0.7 0.00022 21.7 0.0 4.4 3 1 1 4 4 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 ORY19419.1 - 3.7e-10 39.8 0.3 1.5e-05 25.1 0.0 4.3 3 1 1 4 4 4 2 Ankyrin repeats (many copies) AAA_22 PF13401.6 ORY19419.1 - 0.00011 22.4 0.0 0.0016 18.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain Ank PF00023.30 ORY19419.1 - 0.00014 22.1 0.0 13 6.5 0.1 5.2 4 1 0 4 4 4 0 Ankyrin repeat AAA_24 PF13479.6 ORY19419.1 - 0.0029 17.4 0.6 0.4 10.4 0.0 2.8 3 0 0 3 3 3 1 AAA domain DUF2075 PF09848.9 ORY19419.1 - 0.0034 16.7 3.7 0.04 13.2 0.0 3.6 4 0 0 4 4 4 1 Uncharacterized conserved protein (DUF2075) AAA PF00004.29 ORY19419.1 - 0.012 16.0 0.1 1.2 9.6 0.0 4.1 5 0 0 5 5 5 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 ORY19419.1 - 0.014 15.8 0.0 0.072 13.5 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain NB-ARC PF00931.22 ORY19419.1 - 0.018 14.2 0.0 0.098 11.8 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain IstB_IS21 PF01695.17 ORY19419.1 - 0.047 13.4 0.0 1 9.1 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein NTPase_1 PF03266.15 ORY19419.1 - 0.09 12.7 0.0 0.27 11.1 0.0 1.9 1 0 0 1 1 1 0 NTPase DED PF01335.21 ORY19419.1 - 0.25 11.7 4.5 0.49 10.7 0.2 3.2 3 1 0 3 3 3 0 Death effector domain PA28_alpha PF02251.18 ORY19420.1 - 0.096 12.7 0.0 0.15 12.2 0.0 1.2 1 0 0 1 1 1 0 Proteasome activator pa28 alpha subunit Glutaredoxin PF00462.24 ORY19421.1 - 2.2e-19 69.4 0.0 2.2e-18 66.2 0.0 2.6 3 1 0 3 3 3 1 Glutaredoxin Thioredoxin PF00085.20 ORY19421.1 - 4.4e-15 55.5 0.0 9.2e-15 54.5 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 ORY19421.1 - 0.0075 16.6 0.0 0.082 13.2 0.0 2.3 1 1 1 2 2 2 1 Thioredoxin-like OST3_OST6 PF04756.13 ORY19421.1 - 0.069 12.5 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 ORY19421.1 - 0.084 13.3 0.0 0.5 10.8 0.0 2.2 2 1 0 2 2 2 0 Thioredoxin-like domain Thioredoxin_3 PF13192.6 ORY19421.1 - 0.19 11.8 0.0 0.78 9.8 0.0 2.1 2 0 0 2 2 2 0 Thioredoxin domain HSP70 PF00012.20 ORY19422.1 - 8.7e-225 747.5 9.2 9.7e-225 747.3 9.2 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 ORY19422.1 - 3e-15 55.8 0.3 2.7e-14 52.7 0.1 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 ORY19422.1 - 3.2e-05 23.7 0.0 7.6e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DUF4845 PF16137.5 ORY19422.1 - 0.11 13.4 3.1 4.2 8.3 0.0 3.8 3 1 1 4 4 4 0 Domain of unknown function (DUF4845) UQ_con PF00179.26 ORY19423.1 - 8e-25 87.1 0.0 9.7e-25 86.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 ORY19423.1 - 9.8e-07 28.5 0.0 2.6e-06 27.2 0.0 1.7 1 1 1 2 2 2 1 Prokaryotic E2 family B UEV PF05743.13 ORY19423.1 - 0.0038 17.1 0.1 0.0049 16.7 0.1 1.1 1 0 0 1 1 1 1 UEV domain Peroxin-13_N PF04088.13 ORY19424.1 - 3e-54 183.2 0.3 4.4e-54 182.7 0.3 1.2 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_2 PF07653.17 ORY19424.1 - 1.9e-07 30.6 0.0 3.2e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 ORY19424.1 - 3.1e-06 26.7 0.1 7e-06 25.6 0.1 1.6 1 1 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 ORY19424.1 - 0.00055 19.7 0.0 0.00095 19.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain hSH3 PF14603.6 ORY19424.1 - 0.067 13.6 0.0 0.12 12.8 0.0 1.3 1 0 0 1 1 1 0 Helically-extended SH3 domain Pex2_Pex12 PF04757.14 ORY19424.1 - 0.083 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Pex2 / Pex12 amino terminal region DUF2401 PF10287.9 ORY19425.1 - 6.3e-72 241.9 0.0 8e-72 241.5 0.0 1.1 1 0 0 1 1 1 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.9 ORY19425.1 - 0.00045 20.6 0.1 0.0032 17.9 0.0 2.3 2 0 0 2 2 2 1 Glycine-rich protein domain (DUF2403) Ribosomal_S13_N PF08069.12 ORY19426.1 - 1.2e-29 102.1 0.0 2.1e-29 101.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 ORY19426.1 - 1.7e-14 53.8 0.1 2.6e-14 53.2 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.18 ORY19426.1 - 0.015 15.2 0.1 0.031 14.2 0.0 1.6 2 0 0 2 2 2 0 'Paired box' domain Dpy-30 PF05186.13 ORY19427.1 - 4.4e-10 39.1 0.8 6.6e-10 38.5 0.1 1.6 2 0 0 2 2 2 1 Dpy-30 motif TRI12 PF06609.13 ORY19428.1 - 3.6e-54 184.2 14.1 4.3e-54 184.0 14.1 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 ORY19428.1 - 2.9e-21 75.8 25.3 2.9e-21 75.8 25.3 1.7 2 1 0 2 2 2 1 Major Facilitator Superfamily HlyIII PF03006.20 ORY19428.1 - 0.0038 17.0 1.1 0.0038 17.0 1.1 3.0 2 1 1 3 3 3 1 Haemolysin-III related MerR PF00376.23 ORY19429.1 - 0.083 12.7 0.1 0.17 11.7 0.1 1.6 1 0 0 1 1 1 0 MerR family regulatory protein DUF4181 PF13789.6 ORY19430.1 - 0.094 13.0 0.4 0.094 13.0 0.4 2.6 1 1 1 3 3 3 0 Domain of unknown function (DUF4181) LRRC37AB_C PF14914.6 ORY19430.1 - 0.22 11.4 0.9 0.46 10.4 0.9 1.7 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain Oxidored_FMN PF00724.20 ORY19431.1 - 2.4e-39 135.6 0.0 3e-39 135.3 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family ATPase_gene1 PF09527.10 ORY19432.1 - 3.4 7.9 5.4 1.2 9.3 1.1 2.4 2 0 0 2 2 2 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter GFA PF04828.14 ORY19433.1 - 4.3e-08 33.4 0.5 4.3e-08 33.4 0.5 1.5 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme HeLo PF14479.6 ORY19434.1 - 7.7e-07 29.2 0.3 6e-05 23.0 0.3 2.4 1 1 0 1 1 1 1 Prion-inhibition and propagation Pkinase PF00069.25 ORY19434.1 - 0.0002 20.8 0.0 0.00032 20.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 ORY19434.1 - 0.016 14.0 0.1 0.03 13.1 0.1 1.3 1 0 0 1 1 1 0 Fungal protein kinase SesA PF17107.5 ORY19434.1 - 0.038 14.2 1.5 2.8 8.2 0.1 2.3 1 1 1 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Pkinase PF00069.25 ORY19435.1 - 1.2e-20 74.0 0.0 2.1e-20 73.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Ank_2 PF12796.7 ORY19435.1 - 8.7e-19 67.9 0.0 1.4e-05 25.6 0.1 5.0 3 2 3 6 6 6 6 Ankyrin repeats (3 copies) Pkinase_Tyr PF07714.17 ORY19435.1 - 1.3e-18 67.2 0.0 2.5e-18 66.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_4 PF13637.6 ORY19435.1 - 4e-16 59.2 0.1 2.4e-05 24.8 0.1 5.2 5 0 0 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY19435.1 - 3.5e-14 51.5 2.5 0.00014 22.0 0.0 7.7 9 0 0 9 9 9 3 Ankyrin repeat Ank_5 PF13857.6 ORY19435.1 - 1.6e-09 37.8 1.0 0.00048 20.4 0.1 5.2 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Ank PF00023.30 ORY19435.1 - 1.7e-05 25.0 5.6 0.0078 16.6 0.1 6.0 7 0 0 7 7 7 1 Ankyrin repeat Kdo PF06293.14 ORY19435.1 - 0.064 12.6 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Esterase_phd PF10503.9 ORY19436.1 - 1.6e-20 73.5 0.2 2.4e-20 73.0 0.2 1.2 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 ORY19436.1 - 1.5e-12 47.4 0.2 2.1e-12 47.0 0.2 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.28 ORY19436.1 - 0.014 14.2 0.1 0.021 13.7 0.1 1.2 1 0 0 1 1 1 0 Carboxylesterase family Hydrolase_4 PF12146.8 ORY19436.1 - 0.025 13.8 0.2 0.15 11.3 0.1 1.9 1 1 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 ORY19436.1 - 0.064 13.1 0.1 0.16 11.8 0.1 1.8 1 1 0 1 1 1 0 alpha/beta hydrolase fold PH_9 PF15410.6 ORY19437.1 - 0.0019 18.6 0.1 0.011 16.1 0.0 2.4 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 ORY19437.1 - 0.016 15.7 0.3 0.081 13.4 0.0 2.3 2 1 0 2 2 2 0 PH domain BAH PF01426.18 ORY19438.1 - 9.6e-09 35.2 0.0 2.8e-08 33.7 0.0 1.7 2 0 0 2 2 2 1 BAH domain PHD PF00628.29 ORY19438.1 - 0.031 14.2 1.8 0.031 14.2 1.8 2.4 3 0 0 3 3 3 0 PHD-finger Peptidase_M1_N PF17900.1 ORY19439.1 - 0.0092 16.2 0.0 5 7.3 0.0 2.4 2 0 0 2 2 2 2 Peptidase M1 N-terminal domain Peptidase_M1 PF01433.20 ORY19439.1 - 0.12 11.9 0.0 0.28 10.7 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M1 domain Glyco_hydro_28 PF00295.17 ORY19440.1 - 3.1e-99 332.1 20.0 3.9e-99 331.8 20.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 DUF1970 PF09301.10 ORY19440.1 - 0.04 14.2 0.3 0.094 13.0 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1970) 2OG-FeII_Oxy_3 PF13640.6 ORY19441.1 - 2.2e-06 28.5 0.0 5.9e-06 27.1 0.0 1.8 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.16 ORY19442.1 - 9.1e-32 110.3 43.3 1.2e-26 93.5 25.7 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY19442.1 - 4.6e-06 25.8 15.6 6.4e-05 22.0 15.3 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter UPF0715 PF17094.5 ORY19442.1 - 0.4 11.3 0.1 0.4 11.3 0.1 3.3 3 1 1 4 4 4 0 Uncharacterised protein family (UPF0715) DUF1772 PF08592.11 ORY19442.1 - 1 9.7 14.7 6 7.2 5.5 3.5 1 1 2 3 3 3 0 Domain of unknown function (DUF1772) DUF908 PF06012.12 ORY19443.1 - 1.1 8.6 7.0 1.1 8.6 7.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) F_actin_cap_B PF01115.17 ORY19444.1 - 3.6e-106 354.1 0.0 4.1e-106 353.9 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit Peptidase_M10 PF00413.24 ORY19445.1 - 9.6e-18 64.5 0.1 1.8e-17 63.6 0.1 1.5 1 0 0 1 1 1 1 Matrixin Reprolysin_3 PF13582.6 ORY19445.1 - 0.0038 17.7 0.0 0.0094 16.5 0.0 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like DUF4953 PF16313.5 ORY19445.1 - 0.0068 15.7 0.0 0.017 14.4 0.0 1.6 1 0 0 1 1 1 1 Met-zincin Peptidase_M66 PF10462.9 ORY19445.1 - 0.0074 15.3 0.2 0.016 14.2 0.2 1.5 1 0 0 1 1 1 1 Peptidase M66 Peptidase_M54 PF07998.11 ORY19445.1 - 0.023 14.7 0.0 0.046 13.7 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M54 Metallopep PF12044.8 ORY19445.1 - 0.026 13.2 0.0 0.036 12.7 0.0 1.2 1 0 0 1 1 1 0 Putative peptidase family Peptidase_M8 PF01457.16 ORY19445.1 - 0.11 11.2 0.0 0.16 10.6 0.0 1.2 1 0 0 1 1 1 0 Leishmanolysin Astacin PF01400.24 ORY19445.1 - 0.18 11.4 0.3 0.5 9.9 0.0 1.8 2 0 0 2 2 2 0 Astacin (Peptidase family M12A) Fungal_trans PF04082.18 ORY19446.1 - 2.6e-17 62.7 0.4 3.8e-17 62.2 0.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short_C2 PF13561.6 ORY19447.1 - 5.2e-24 85.1 0.0 6.7e-24 84.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY19447.1 - 3.6e-15 55.9 0.0 4.4e-15 55.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORY19447.1 - 5.6e-06 26.4 0.0 9.2e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 KR domain MutS_V PF00488.21 ORY19448.1 - 2.3e-72 243.0 0.0 3.6e-72 242.4 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 ORY19448.1 - 4.9e-42 144.3 5.8 1.1e-41 143.1 5.8 1.7 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 ORY19448.1 - 3.9e-20 72.2 0.0 9.9e-20 70.9 0.0 1.7 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 ORY19448.1 - 1.3e-10 41.7 0.1 1.7e-09 38.1 0.0 2.7 3 0 0 3 3 3 1 MutS domain II AAA_23 PF13476.6 ORY19448.1 - 0.089 13.3 1.2 1.9 9.0 0.0 2.6 2 1 0 2 2 2 0 AAA domain AAA_14 PF13173.6 ORY19448.1 - 0.17 11.9 0.0 0.86 9.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain URO-D PF01208.17 ORY19449.1 - 3.7e-128 427.5 0.0 4.2e-128 427.3 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) Pex26 PF07163.12 ORY19449.1 - 0.14 11.4 0.1 0.22 10.8 0.1 1.2 1 0 0 1 1 1 0 Pex26 protein dCMP_cyt_deam_1 PF00383.23 ORY19450.1 - 3.6e-23 81.4 0.0 5.1e-23 80.9 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 ORY19450.1 - 8.8e-23 80.6 0.1 1.1e-22 80.3 0.1 1.1 1 0 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 ORY19450.1 - 4.2e-06 26.9 2.2 0.019 15.0 0.7 2.2 1 1 1 2 2 2 2 Bd3614-like deaminase APOBEC2 PF18772.1 ORY19450.1 - 0.00057 20.0 0.3 0.018 15.1 0.3 2.0 1 1 0 1 1 1 1 APOBEC2 SNAD4 PF18750.1 ORY19450.1 - 0.0008 19.5 0.0 0.0021 18.1 0.0 1.6 2 0 0 2 2 2 1 Secreted Novel AID/APOBEC-like Deaminase 4 NAD2 PF18782.1 ORY19450.1 - 0.0016 18.6 0.0 0.0098 16.0 0.0 1.9 1 1 0 1 1 1 1 Novel AID APOBEC clade 2 NAD1 PF18778.1 ORY19450.1 - 0.0023 18.0 0.3 0.041 14.0 0.0 2.0 1 1 1 2 2 2 1 Novel AID APOBEC clade 1 APOBEC_N PF08210.11 ORY19450.1 - 0.0025 17.7 0.2 0.018 15.0 0.2 1.9 1 1 0 1 1 1 1 APOBEC-like N-terminal domain XOO_2897-deam PF14440.6 ORY19450.1 - 0.014 15.5 0.1 0.027 14.6 0.0 1.5 2 0 0 2 2 2 0 Xanthomonas XOO_2897-like deaminase APOBEC3 PF18771.1 ORY19450.1 - 0.042 14.0 0.0 0.087 13.0 0.0 1.6 1 1 0 1 1 1 0 APOBEC3 DnaJ_C PF01556.18 ORY19451.1 - 7.7e-40 136.4 0.2 1e-39 136.0 0.2 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 ORY19451.1 - 2.3e-25 88.5 2.1 4.1e-25 87.7 2.1 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 ORY19451.1 - 3.8e-16 59.2 17.9 6.2e-16 58.5 17.9 1.4 1 0 0 1 1 1 1 DnaJ central domain DUF1356 PF07092.12 ORY19451.1 - 0.12 11.6 2.1 2.1 7.5 0.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1356) DUF2614 PF11023.8 ORY19451.1 - 0.4 10.8 6.3 4.3 7.5 0.7 2.2 1 1 1 2 2 2 0 Zinc-ribbon containing domain HypA PF01155.19 ORY19451.1 - 0.54 10.3 10.0 0.52 10.4 1.9 2.4 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_9 PF14369.6 ORY19451.1 - 0.61 10.4 2.7 54 4.2 0.0 3.3 3 0 0 3 3 3 0 zinc-ribbon Anti-TRAP PF15777.5 ORY19451.1 - 0.95 9.5 15.9 0.44 10.5 1.5 2.6 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein Zn_ribbon_SprT PF17283.2 ORY19451.1 - 1.3 9.0 4.5 2.4 8.1 1.8 2.5 2 0 0 2 2 2 0 SprT-like zinc ribbon domain zinc-ribbons_6 PF07191.12 ORY19451.1 - 2.4 8.2 8.8 6.2 6.9 1.9 2.2 1 1 1 2 2 2 0 zinc-ribbons Zn_Tnp_IS1595 PF12760.7 ORY19451.1 - 5.7 7.0 8.6 8.8 6.4 1.5 2.5 2 0 0 2 2 2 0 Transposase zinc-ribbon domain GH131_N PF18271.1 ORY19452.1 - 2.9e-67 227.1 0.0 3.6e-63 213.7 0.0 2.0 1 1 1 2 2 2 2 Glycoside hydrolase 131 catalytic N-terminal domain HVSL PF09749.9 ORY19453.1 - 1.5e-63 214.5 0.0 9.2e-63 211.9 0.0 1.8 1 1 0 1 1 1 1 Uncharacterised conserved protein Pal1 PF08316.11 ORY19454.1 - 2.5e-10 41.2 0.5 6.2e-10 40.0 0.1 1.9 2 0 0 2 2 2 1 Pal1 cell morphology protein Abhydrolase_6 PF12697.7 ORY19455.1 - 4.7e-12 47.0 0.1 6.4e-12 46.5 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORY19455.1 - 2.6e-08 33.5 0.0 3.3e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ORY19455.1 - 3.7e-08 33.3 0.0 4.9e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.13 ORY19455.1 - 0.005 16.6 0.0 0.0074 16.0 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Palm_thioest PF02089.15 ORY19455.1 - 0.011 15.6 0.0 0.014 15.2 0.0 1.1 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Thioesterase PF00975.20 ORY19455.1 - 0.02 15.0 0.0 0.042 14.0 0.0 1.5 1 1 0 1 1 1 0 Thioesterase domain Ser_hydrolase PF06821.13 ORY19455.1 - 0.084 12.7 0.0 0.23 11.3 0.0 1.6 2 0 0 2 2 2 0 Serine hydrolase MTABC_N PF16185.5 ORY19456.1 - 0.024 14.1 0.3 0.034 13.7 0.3 1.1 1 0 0 1 1 1 0 Mitochondrial ABC-transporter N-terminal five TM region DUF1097 PF06496.11 ORY19458.1 - 0.18 11.9 4.2 0.26 11.4 4.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1097) Ins_allergen_rp PF06757.13 ORY19460.1 - 0.061 13.3 0.1 0.15 12.0 0.0 1.6 2 0 0 2 2 2 0 Insect allergen related repeat, nitrile-specifier detoxification E1-E2_ATPase PF00122.20 ORY19463.1 - 0.0084 15.6 0.5 0.013 15.0 0.5 1.2 1 0 0 1 1 1 1 E1-E2 ATPase zf-CCCH PF00642.24 ORY19464.1 - 8.6e-23 79.7 30.9 3.9e-06 26.6 0.2 5.6 4 1 1 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 ORY19464.1 - 3.1e-20 71.5 30.8 2.3e-06 27.5 1.8 5.3 5 0 0 5 5 5 5 Zinc finger domain Torus PF16131.5 ORY19464.1 - 3.9e-11 43.6 29.4 0.00019 22.1 0.8 5.7 2 1 4 6 6 6 5 Torus domain zf-CCCH_4 PF18044.1 ORY19464.1 - 9e-10 38.1 31.4 0.00012 21.8 0.5 5.4 5 0 0 5 5 5 4 CCCH-type zinc finger zf-CCCH_3 PF15663.5 ORY19464.1 - 0.00012 22.2 16.2 0.001 19.3 5.5 2.8 1 1 1 2 2 2 2 Zinc-finger containing family zinc_ribbon_9 PF14369.6 ORY19464.1 - 0.7 10.2 4.9 3.4 8.0 0.6 2.7 2 0 0 2 2 2 0 zinc-ribbon GRP PF07172.11 ORY19464.1 - 1.3 9.8 6.7 1.9 9.2 6.7 1.2 1 0 0 1 1 1 0 Glycine rich protein family Glyco_hydro_18 PF00704.28 ORY19466.1 - 2.8e-74 250.7 0.0 3.4e-74 250.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Vps53_N PF04100.12 ORY19467.1 - 6.8e-106 354.4 2.3 6.8e-106 354.4 2.3 1.8 2 0 0 2 2 2 1 Vps53-like, N-terminal Vps54_N PF10475.9 ORY19467.1 - 1e-07 31.6 2.8 1.8e-07 30.8 2.8 1.3 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex DUF2451 PF10474.9 ORY19467.1 - 0.00067 19.5 0.0 0.0018 18.1 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) Zw10 PF06248.13 ORY19467.1 - 0.0044 15.7 2.8 0.0082 14.8 2.8 1.4 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 VPS53_C PF16854.5 ORY19467.1 - 0.022 14.6 0.0 0.18 11.7 0.0 2.3 1 1 1 2 2 2 0 Vacuolar protein sorting-associated protein 53 C-terminus COG2 PF06148.11 ORY19467.1 - 0.12 12.4 3.7 0.41 10.7 0.8 3.2 3 1 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 MitMem_reg PF13012.6 ORY19467.1 - 0.27 11.7 2.0 3 8.3 0.0 2.7 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function APG6_N PF17675.1 ORY19467.1 - 0.53 10.8 3.8 0.77 10.3 2.3 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region CBFB_NFYA PF02045.15 ORY19469.1 - 2.4e-28 98.5 3.3 6.6e-28 97.1 3.3 1.8 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B TFIIA PF03153.13 ORY19469.1 - 0.079 12.9 33.0 0.11 12.5 33.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SWIRM-assoc_2 PF16496.5 ORY19469.1 - 0.53 9.1 7.3 1 8.2 7.3 1.3 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal TFIIE-A_C PF11521.8 ORY19469.1 - 1.4 9.2 7.6 9 6.7 4.9 2.6 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha MFS_1 PF07690.16 ORY19471.1 - 3.9e-30 105.0 28.3 3.9e-30 105.0 28.3 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Saf_2TM PF18303.1 ORY19471.1 - 3.2 7.3 8.2 14 5.2 0.0 3.5 4 0 0 4 4 4 0 SAVED-fused 2TM effector domain SH3_1 PF00018.28 ORY19472.1 - 3.2e-35 119.5 7.5 2.8e-12 46.1 0.1 4.4 4 0 0 4 4 4 3 SH3 domain SHD1 PF03983.12 ORY19472.1 - 2.5e-33 113.7 0.0 4.3e-33 113.0 0.0 1.4 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_9 PF14604.6 ORY19472.1 - 9.3e-33 111.9 8.7 2.8e-12 46.3 0.2 3.9 4 0 0 4 4 4 3 Variant SH3 domain SH3_2 PF07653.17 ORY19472.1 - 6.7e-24 83.3 0.0 5.7e-08 32.3 0.0 4.5 4 0 0 4 4 4 3 Variant SH3 domain DUF1720 PF08226.11 ORY19472.1 - 1.7e-06 28.3 162.7 0.00012 22.4 36.2 6.3 1 1 3 4 4 4 3 Domain of unknown function (DUF1720) SAM_4 PF18017.1 ORY19472.1 - 0.00041 20.3 0.0 0.00096 19.1 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_3 PF08239.11 ORY19472.1 - 0.00073 19.8 5.3 0.31 11.3 0.7 3.1 3 0 0 3 3 3 2 Bacterial SH3 domain SH3_10 PF17902.1 ORY19472.1 - 0.0018 18.3 0.0 0.15 12.1 0.0 3.0 3 0 0 3 3 3 1 SH3 domain HTH_32 PF13565.6 ORY19473.1 - 0.084 13.5 0.0 0.17 12.5 0.0 1.7 1 1 0 1 1 1 0 Homeodomain-like domain Sugar_tr PF00083.24 ORY19474.1 - 2.7e-125 418.8 23.2 3.1e-125 418.6 23.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY19474.1 - 2.3e-19 69.5 28.3 2.3e-19 69.5 28.3 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily dUTPase PF00692.19 ORY19476.1 - 2.8e-35 120.8 0.0 3.9e-35 120.3 0.0 1.3 1 0 0 1 1 1 1 dUTPase ECH_1 PF00378.20 ORY19476.1 - 0.025 13.9 0.0 0.031 13.6 0.0 1.1 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase Phos_pyr_kin PF08543.12 ORY19477.1 - 2e-10 40.5 0.0 4.6e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 ORY19477.1 - 6.4e-06 25.7 0.2 1.7e-05 24.2 0.0 1.8 3 0 0 3 3 3 1 pfkB family carbohydrate kinase PCNA_N PF00705.18 ORY19478.1 - 2.7e-55 185.5 7.1 2.8e-55 185.4 4.2 2.0 2 1 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 ORY19478.1 - 1.3e-53 180.5 0.0 1.2e-52 177.4 0.0 2.0 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.13 ORY19478.1 - 8.7e-08 31.9 0.1 1.1e-07 31.6 0.1 1.1 1 0 0 1 1 1 1 Rad9 Rad1 PF02144.16 ORY19478.1 - 3.9e-06 26.2 0.4 0.00044 19.4 0.4 2.1 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Hus1 PF04005.12 ORY19478.1 - 1.6e-05 24.2 0.1 0.00049 19.3 0.0 2.0 2 0 0 2 2 2 1 Hus1-like protein Rab5ip PF07019.12 ORY19479.1 - 5.8e-29 100.5 3.8 6.8e-29 100.3 3.8 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) Vezatin PF12632.7 ORY19481.1 - 1.1e-71 241.6 0.1 1.6e-71 241.0 0.1 1.3 1 0 0 1 1 1 1 Mysoin-binding motif of peroxisomes Rubella_Capsid PF05750.11 ORY19481.1 - 0.11 12.1 4.6 0.11 12.0 2.0 2.1 2 0 0 2 2 2 0 Rubella capsid protein zf-C2H2_4 PF13894.6 ORY19483.1 - 1.8e-05 25.2 4.8 0.0041 17.8 1.4 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 ORY19483.1 - 7.4e-05 23.0 1.9 7.4e-05 23.0 1.9 3.2 2 1 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 ORY19483.1 - 0.06 13.4 0.1 0.06 13.4 0.1 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger zf-BED PF02892.15 ORY19483.1 - 0.063 13.3 0.8 0.063 13.3 0.8 2.3 1 1 1 2 2 2 0 BED zinc finger TF_Zn_Ribbon PF08271.12 ORY19483.1 - 0.085 12.4 0.8 16 5.1 0.1 2.5 2 0 0 2 2 2 0 TFIIB zinc-binding C5HCH PF17982.1 ORY19483.1 - 0.14 12.3 0.4 0.14 12.3 0.4 2.0 1 1 1 2 2 2 0 NSD Cys-His rich domain DUF1610 PF07754.11 ORY19483.1 - 0.75 9.8 3.3 2.2 8.3 1.3 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF1610) zf-C2HC_2 PF13913.6 ORY19483.1 - 0.99 9.4 3.7 2.6 8.1 0.3 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Zn-ribbon_8 PF09723.10 ORY19483.1 - 1.5 9.0 6.0 7.3 6.8 6.0 2.1 1 1 0 1 1 1 0 Zinc ribbon domain OrfB_Zn_ribbon PF07282.11 ORY19483.1 - 2.4 8.2 5.5 47 4.0 5.5 2.3 1 1 0 1 1 1 0 Putative transposase DNA-binding domain VRR_NUC PF08774.11 ORY19485.1 - 5.5e-23 81.1 0.0 2.7e-22 78.9 0.0 2.1 2 0 0 2 2 2 1 VRR-NUC domain Glyco_transf_9 PF01075.17 ORY19485.1 - 0.0073 15.7 0.6 0.013 14.8 0.6 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 9 (heptosyltransferase) MFS_1 PF07690.16 ORY19486.1 - 2.8e-34 118.6 22.6 1.3e-25 90.1 10.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 ORY19486.1 - 1.7e-05 23.6 6.4 1.7e-05 23.6 6.4 2.5 2 1 1 3 3 3 1 MFS/sugar transport protein MFS_1_like PF12832.7 ORY19486.1 - 2.4e-05 23.4 6.2 0.00015 20.8 4.6 2.1 2 0 0 2 2 2 1 MFS_1 like family Sugar_tr PF00083.24 ORY19486.1 - 0.00058 18.8 9.9 0.05 12.5 7.1 2.4 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_3 PF05977.13 ORY19486.1 - 0.0055 15.2 9.7 0.0073 14.8 3.0 2.1 2 0 0 2 2 2 2 Transmembrane secretion effector OATP PF03137.20 ORY19486.1 - 0.15 10.3 5.6 0.4 8.9 0.1 2.5 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family SNN_linker PF09050.10 ORY19486.1 - 2.5 8.0 8.2 0.11 12.4 1.1 2.3 2 0 0 2 2 2 0 Stannin unstructured linker Amidase PF01425.21 ORY19487.1 - 2.2e-38 132.4 0.0 4e-38 131.5 0.0 1.3 1 1 0 1 1 1 1 Amidase MIS13 PF08202.11 ORY19488.1 - 1.2e-49 169.2 0.0 2.3e-49 168.3 0.0 1.4 1 0 0 1 1 1 1 Mis12-Mtw1 protein family DUF5610 PF18433.1 ORY19488.1 - 0.013 16.0 0.0 0.042 14.4 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF5610) PS_Dcarbxylase PF02666.15 ORY19489.1 - 3.7e-53 180.0 0.0 5.5e-53 179.5 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.30 ORY19489.1 - 1.6e-43 147.2 0.1 3e-21 75.6 0.0 2.6 2 0 0 2 2 2 2 C2 domain YL1 PF05764.13 ORY19489.1 - 0.00046 20.4 9.6 0.0009 19.4 9.6 1.4 1 0 0 1 1 1 1 YL1 nuclear protein EF-hand_1 PF00036.32 ORY19489.1 - 0.009 15.5 0.7 0.033 13.7 0.1 2.4 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 ORY19489.1 - 0.038 14.4 0.2 0.038 14.4 0.2 2.5 2 0 0 2 2 1 0 EF-hand domain pair EF-hand_6 PF13405.6 ORY19489.1 - 0.062 13.3 4.7 0.11 12.5 0.1 3.1 3 0 0 3 3 3 0 EF-hand domain NOA36 PF06524.12 ORY19489.1 - 0.4 9.9 9.1 0.77 9.0 9.1 1.5 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.14 ORY19489.1 - 0.88 7.8 14.5 1.4 7.1 14.5 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 ORY19489.1 - 1.4 7.1 12.5 2.2 6.4 12.5 1.2 1 0 0 1 1 1 0 Nop14-like family DUF3381 PF11861.8 ORY19489.1 - 1.5 8.6 13.5 2.7 7.8 13.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) SURF2 PF05477.11 ORY19489.1 - 1.7 8.3 9.4 3.9 7.1 9.4 1.5 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Nop53 PF07767.11 ORY19489.1 - 3.7 6.8 16.1 6.3 6.1 16.1 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) PBP1_TM PF14812.6 ORY19489.1 - 5.2 7.5 13.9 19 5.7 13.9 2.0 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal HAD PF12710.7 ORY19490.1 - 3.9e-21 76.3 0.0 5.7e-21 75.8 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 ORY19490.1 - 0.0036 16.7 0.0 0.019 14.4 0.0 1.9 1 1 0 1 1 1 1 Putative Phosphatase Hydrolase PF00702.26 ORY19490.1 - 0.012 15.9 0.1 0.03 14.6 0.0 1.8 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.12 ORY19490.1 - 0.019 14.5 0.0 0.037 13.5 0.0 1.5 1 0 0 1 1 1 0 Pyrimidine 5'-nucleotidase (UMPH-1) Acid_phosphat_B PF03767.14 ORY19490.1 - 0.074 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) Bin3 PF06859.12 ORY19491.1 - 0.081 13.6 0.1 6.4 7.5 0.0 2.2 2 0 0 2 2 2 0 Bicoid-interacting protein 3 (Bin3) G-alpha PF00503.20 ORY19492.1 - 3.2e-122 408.1 2.3 3.7e-122 407.9 2.3 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 ORY19492.1 - 4.7e-15 55.5 2.5 2.4e-10 40.1 0.1 2.6 2 0 0 2 2 2 2 ADP-ribosylation factor family zf-CHC2 PF01807.20 ORY19492.1 - 0.0004 20.1 0.0 0.0018 18.1 0.0 2.0 2 0 0 2 2 2 1 CHC2 zinc finger Gtr1_RagA PF04670.12 ORY19492.1 - 0.0027 17.1 4.2 0.062 12.6 0.1 2.7 2 1 0 2 2 2 1 Gtr1/RagA G protein conserved region AAA_29 PF13555.6 ORY19492.1 - 0.018 14.8 0.0 0.045 13.5 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Roc PF08477.13 ORY19492.1 - 0.021 15.0 0.2 2.4 8.4 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 ORY19492.1 - 0.081 12.4 0.0 1.4 8.4 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain MCM PF00493.23 ORY19492.1 - 0.083 12.0 0.0 0.15 11.1 0.0 1.4 1 0 0 1 1 1 0 MCM P-loop domain MMR_HSR1 PF01926.23 ORY19492.1 - 0.14 12.3 0.1 9 6.4 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 ORY19492.1 - 0.14 11.5 0.0 0.32 10.3 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family Transketolase_N PF00456.21 ORY19495.1 - 1.1e-156 520.9 0.1 1.5e-156 520.5 0.1 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 ORY19495.1 - 8.1e-45 152.7 0.1 1.4e-44 151.9 0.1 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 ORY19495.1 - 2.1e-14 53.5 0.0 4.5e-14 52.4 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 ORY19495.1 - 5.5e-06 25.8 0.0 9.6e-06 25.0 0.0 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Beta_elim_lyase PF01212.21 ORY19495.1 - 0.084 12.1 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase GtrA PF04138.14 ORY19495.1 - 0.089 13.0 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 GtrA-like protein zf-RING_13 PF17977.1 ORY19495.1 - 0.17 12.1 1.7 0.34 11.1 0.2 2.3 2 1 1 3 3 3 0 RING/Ubox like zinc-binding domain Beta-lactamase PF00144.24 ORY19496.1 - 1.3e-33 116.6 0.0 1.8e-33 116.2 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Par3_HAL_N_term PF12053.8 ORY19496.1 - 0.065 13.5 0.1 0.12 12.6 0.1 1.4 1 0 0 1 1 1 0 N-terminal of Par3 and HAL proteins CDC24_OB3 PF17244.2 ORY19497.1 - 0.0004 20.2 0.2 0.015 15.0 0.0 2.7 3 0 0 3 3 3 1 Cell division control protein 24, OB domain 3 NAD_binding_5 PF07994.12 ORY19498.1 - 7.2e-132 439.6 0.1 9.2e-132 439.3 0.1 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 ORY19498.1 - 6.4e-45 151.9 0.3 1.4e-44 150.8 0.3 1.6 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase LIM PF00412.22 ORY19499.1 - 2.4e-20 72.5 21.4 3e-11 43.4 3.1 2.8 3 0 0 3 3 3 2 LIM domain WRC PF08879.10 ORY19499.1 - 0.2 11.4 3.0 3.2 7.5 0.5 2.5 2 0 0 2 2 2 0 WRC Vps36-NZF-N PF16988.5 ORY19499.1 - 0.2 11.1 2.3 0.54 9.7 0.2 2.6 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain DUF2321 PF10083.9 ORY19499.1 - 9.7 5.8 8.4 0.51 10.0 0.7 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) GST_N_4 PF17172.4 ORY19500.1 - 1.1e-19 71.0 0.1 2.5e-19 69.8 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 ORY19500.1 - 1.2e-11 44.2 0.0 2.1e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 ORY19500.1 - 1.1e-10 41.9 0.1 1.7e-10 41.3 0.1 1.3 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein SAM35 PF10806.8 ORY19500.1 - 5.7e-06 26.6 0.1 2e-05 24.8 0.0 1.8 1 1 0 2 2 2 1 SAM35, subunit of SAM coomplex GST_C_2 PF13410.6 ORY19500.1 - 0.029 14.4 0.6 0.06 13.4 0.6 1.6 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Methyltransf_12 PF08242.12 ORY19501.1 - 6.9e-11 42.8 0.1 2.1e-09 38.0 0.1 2.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY19501.1 - 2.3e-10 40.5 0.0 3.9e-09 36.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY19501.1 - 4.1e-09 37.0 0.2 2.7e-06 28.0 0.2 3.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY19501.1 - 6.3e-08 33.2 0.1 0.0087 16.7 0.0 2.9 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 ORY19501.1 - 2.3e-07 30.7 0.1 7.1e-06 25.9 0.0 2.7 2 1 1 3 3 3 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORY19501.1 - 0.0046 16.3 0.0 0.018 14.3 0.0 1.8 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_33 PF10017.9 ORY19501.1 - 0.0094 15.1 0.0 0.017 14.3 0.0 1.3 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent Methyltransf_7 PF03492.15 ORY19501.1 - 0.051 12.8 0.0 0.093 11.9 0.0 1.3 1 0 0 1 1 1 0 SAM dependent carboxyl methyltransferase Methyltransf_32 PF13679.6 ORY19501.1 - 0.18 11.8 0.0 0.32 11.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_PK PF05891.12 ORY19501.1 - 0.19 11.2 0.0 0.93 9.0 0.0 1.9 1 1 1 2 2 2 0 AdoMet dependent proline di-methyltransferase UcrQ PF02939.16 ORY19502.1 - 1.2e-33 114.9 0.2 1.4e-33 114.7 0.2 1.0 1 0 0 1 1 1 1 UcrQ family Cyt_b-c1_8 PF10890.8 ORY19502.1 - 0.088 13.2 0.0 0.16 12.4 0.0 1.5 1 1 0 1 1 1 0 Cytochrome b-c1 complex subunit 8 Band_7 PF01145.25 ORY19503.1 - 3.3e-25 89.1 7.3 6.8e-25 88.1 7.3 1.5 1 1 0 1 1 1 1 SPFH domain / Band 7 family YdfA_immunity PF12127.8 ORY19503.1 - 4.6e-05 22.7 3.4 6.5e-05 22.2 3.4 1.3 1 0 0 1 1 1 1 SigmaW regulon antibacterial GatB_Yqey PF02637.18 ORY19503.1 - 0.057 13.3 1.8 0.089 12.7 1.8 1.4 1 0 0 1 1 1 0 GatB domain zf-C2H2_aberr PF17017.5 ORY19505.1 - 0.0017 18.6 0.1 0.0017 18.6 0.1 1.8 2 0 0 2 2 2 1 Aberrant zinc-finger zf-C2H2 PF00096.26 ORY19505.1 - 0.019 15.4 15.4 0.98 10.0 0.2 4.2 3 0 0 3 3 3 0 Zinc finger, C2H2 type APG6_N PF17675.1 ORY19505.1 - 0.21 12.1 4.8 0.52 10.8 4.8 1.6 1 0 0 1 1 1 0 Apg6 coiled-coil region HAUS-augmin3 PF14932.6 ORY19505.1 - 0.31 10.6 2.7 0.52 9.8 2.7 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Cwf_Cwc_15 PF04889.12 ORY19505.1 - 0.57 9.9 10.1 0.17 11.6 3.7 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein MerR_1 PF13411.6 ORY19507.1 - 0.066 13.3 0.2 5.1 7.3 0.2 2.5 2 0 0 2 2 2 0 MerR HTH family regulatory protein MFS_1 PF07690.16 ORY19509.1 - 5.9e-38 130.7 53.4 5.9e-38 130.7 53.4 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF3493 PF11998.8 ORY19509.1 - 0.27 11.4 1.7 1.4 9.2 0.0 3.1 3 0 0 3 3 3 0 Low psii accumulation1 / Rep27 DUF1264 PF06884.11 ORY19510.1 - 2e-71 239.1 1.5 1.3e-46 158.3 0.4 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF1264) DUF4598 PF15370.6 ORY19511.1 - 2e-20 73.3 10.0 4.6e-19 68.9 0.5 3.1 2 1 0 2 2 2 2 Domain of unknown function (DUF4598) IMUP PF15761.5 ORY19511.1 - 0.0024 18.5 5.1 0.0051 17.5 5.1 1.6 1 0 0 1 1 1 1 Immortalisation up-regulated protein DUF1955 PF09205.10 ORY19511.1 - 0.017 14.9 0.1 0.023 14.5 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1955) AF-4 PF05110.13 ORY19511.1 - 0.05 11.7 5.6 0.047 11.8 5.6 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein NAM-associated PF14303.6 ORY19511.1 - 2 9.1 6.2 2.6 8.7 5.6 1.6 1 1 0 1 1 1 0 No apical meristem-associated C-terminal domain IF4E PF01652.18 ORY19512.1 - 1.7e-32 112.4 0.4 2.7e-32 111.8 0.4 1.3 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Fungal_trans_2 PF11951.8 ORY19513.1 - 5.6e-07 28.7 0.1 8.2e-07 28.2 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY19513.1 - 2.1e-05 24.6 11.1 3.9e-05 23.7 11.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GST_C PF00043.25 ORY19514.1 - 3.9e-10 39.8 0.0 5.8e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 ORY19514.1 - 4.2e-08 33.1 0.1 2e-07 30.9 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 ORY19514.1 - 2.8e-07 30.8 0.0 4.3e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 ORY19514.1 - 3.5e-07 30.6 0.0 5.6e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 ORY19514.1 - 3.5e-06 27.1 0.0 8e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 ORY19514.1 - 1.6e-05 25.1 0.0 2.9e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain HET PF06985.11 ORY19515.1 - 7.7e-28 97.7 0.0 1.3e-27 96.9 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MAP65_ASE1 PF03999.12 ORY19517.1 - 2.1e-76 257.9 7.4 3.3e-75 254.0 8.1 2.0 1 1 1 2 2 2 2 Microtubule associated protein (MAP65/ASE1 family) DUF1140 PF06600.11 ORY19517.1 - 0.12 12.8 0.0 0.39 11.2 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1140) DUF4314 PF14192.6 ORY19517.1 - 0.2 11.6 0.0 0.49 10.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4314) BLOC1_2 PF10046.9 ORY19517.1 - 1.6 9.1 4.4 25 5.2 0.0 4.0 4 0 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 APG6_N PF17675.1 ORY19517.1 - 9.3 6.8 31.6 0.16 12.5 10.6 4.0 2 1 2 4 4 4 0 Apg6 coiled-coil region HET PF06985.11 ORY19521.1 - 6.4e-23 81.7 0.1 7.6e-23 81.5 0.1 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HET PF06985.11 ORY19522.1 - 6.5e-12 46.0 0.2 1.1e-11 45.3 0.2 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ebp2 PF05890.12 ORY19523.1 - 5e-95 318.1 9.3 5e-95 318.1 9.3 2.1 2 0 0 2 2 2 1 Eukaryotic rRNA processing protein EBP2 HSBP1 PF06825.12 ORY19524.1 - 6e-20 70.8 0.2 7e-20 70.6 0.2 1.1 1 0 0 1 1 1 1 Heat shock factor binding protein 1 SRA1 PF07304.11 ORY19524.1 - 0.0027 17.5 0.0 0.0029 17.4 0.0 1.0 1 0 0 1 1 1 1 Steroid receptor RNA activator (SRA1) Matrilin_ccoil PF10393.9 ORY19524.1 - 0.022 14.6 0.4 0.076 12.9 0.4 1.8 1 1 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin CLZ PF16526.5 ORY19524.1 - 0.044 14.2 0.4 0.051 13.9 0.4 1.1 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ANAPC4 PF12896.7 ORY19524.1 - 0.051 13.1 0.0 0.056 12.9 0.0 1.0 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 4 Corona_S2 PF01601.16 ORY19524.1 - 0.056 11.9 0.1 0.061 11.8 0.1 1.0 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein BLOC1_2 PF10046.9 ORY19524.1 - 0.07 13.4 0.2 0.094 13.0 0.2 1.2 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3510 PF12022.8 ORY19524.1 - 0.083 13.3 0.0 0.087 13.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3510) Trimer_CC PF08954.11 ORY19524.1 - 0.13 11.9 0.4 0.42 10.2 0.4 2.2 1 1 0 1 1 1 0 Trimerisation motif Thioredoxin PF00085.20 ORY19525.1 - 3.1e-61 203.8 0.1 4.7e-32 110.0 0.0 2.2 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.12 ORY19525.1 - 6.9e-25 87.8 1.9 2.3e-24 86.1 0.8 2.2 2 0 0 2 2 2 1 Endoplasmic reticulum protein ERp29, C-terminal domain OST3_OST6 PF04756.13 ORY19525.1 - 5.5e-18 65.3 0.0 7.2e-09 35.4 0.0 2.1 1 1 1 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 ORY19525.1 - 4.4e-17 62.5 0.0 3.9e-09 36.9 0.0 2.8 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 ORY19525.1 - 9.5e-10 38.5 0.0 0.00025 21.2 0.0 2.7 2 0 0 2 2 2 2 Thioredoxin-like ERp29_N PF07912.13 ORY19525.1 - 1e-08 35.4 0.1 7e-05 23.0 0.0 2.7 2 1 0 2 2 2 2 ERp29, N-terminal domain Thioredoxin_8 PF13905.6 ORY19525.1 - 1.3e-08 35.0 0.0 0.0041 17.4 0.0 3.5 3 1 1 4 4 3 2 Thioredoxin-like AhpC-TSA PF00578.21 ORY19525.1 - 9.6e-08 32.0 0.0 0.0015 18.5 0.0 2.6 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_6 PF13848.6 ORY19525.1 - 9e-07 29.0 0.1 0.0026 17.7 0.0 2.7 2 1 0 2 2 2 2 Thioredoxin-like domain HyaE PF07449.11 ORY19525.1 - 4.2e-06 26.7 0.0 0.0086 16.0 0.0 2.8 3 0 0 3 3 3 2 Hydrogenase-1 expression protein HyaE Redoxin PF08534.10 ORY19525.1 - 5.2e-06 26.2 0.2 0.031 14.0 0.0 2.3 2 0 0 2 2 2 2 Redoxin Thioredoxin_9 PF14595.6 ORY19525.1 - 2.4e-05 24.1 0.0 0.033 14.0 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin TraF PF13728.6 ORY19525.1 - 3.7e-05 23.6 0.0 0.059 13.2 0.0 2.3 2 0 0 2 2 2 2 F plasmid transfer operon protein Thioredoxin_3 PF13192.6 ORY19525.1 - 0.0073 16.3 0.0 2 8.5 0.0 2.5 2 0 0 2 2 2 1 Thioredoxin domain Glutaredoxin PF00462.24 ORY19525.1 - 0.015 15.5 1.0 4.8 7.5 0.1 2.9 2 2 0 2 2 2 0 Glutaredoxin Thioredoxin_4 PF13462.6 ORY19525.1 - 0.07 13.3 0.5 32 4.6 0.1 3.3 2 2 2 4 4 4 0 Thioredoxin Thioredoxin PF00085.20 ORY19526.1 - 6.5e-25 87.1 0.1 1.5e-24 85.9 0.0 1.6 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_8 PF13905.6 ORY19526.1 - 2.8e-07 30.8 0.0 6.5e-06 26.4 0.0 2.1 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 ORY19526.1 - 2.1e-06 28.2 0.1 6.7e-06 26.5 0.1 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 ORY19526.1 - 0.00013 21.4 0.0 0.00014 21.3 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 ORY19526.1 - 0.00022 21.3 0.0 0.00036 20.7 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 ORY19526.1 - 0.00097 19.1 0.1 0.01 15.7 0.1 2.2 1 1 1 2 2 2 1 AhpC/TSA family Redoxin PF08534.10 ORY19526.1 - 0.013 15.3 0.7 0.13 12.0 0.6 2.1 1 1 1 2 2 2 0 Redoxin Thioredoxin_9 PF14595.6 ORY19526.1 - 0.018 14.8 0.0 0.03 14.1 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin TraF PF13728.6 ORY19526.1 - 0.028 14.2 0.9 0.029 14.2 0.0 1.4 2 0 0 2 2 2 0 F plasmid transfer operon protein HyaE PF07449.11 ORY19526.1 - 0.051 13.5 0.0 0.087 12.8 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Thioredox_DsbH PF03190.15 ORY19526.1 - 0.07 13.1 0.0 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF255 WD40 PF00400.32 ORY19527.1 - 5.7e-27 93.4 7.2 6.8e-06 26.7 0.0 8.2 8 0 0 8 8 8 5 WD domain, G-beta repeat Nudix_N_2 PF14803.6 ORY19527.1 - 0.078 12.9 1.2 0.34 10.8 1.1 2.2 2 0 0 2 2 2 0 Nudix N-terminal MFS_1 PF07690.16 ORY19528.1 - 1.2e-25 90.3 35.2 1.2e-25 90.3 35.2 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Ac76 PF05814.11 ORY19528.1 - 0.055 13.5 0.3 0.15 12.1 0.3 1.7 1 0 0 1 1 1 0 Orf76 (Ac76) COesterase PF00135.28 ORY19530.1 - 1.3e-64 219.0 0.7 2.5e-49 168.5 0.3 3.0 1 1 2 3 3 3 3 Carboxylesterase family PAH PF02671.21 ORY19531.1 - 4.2e-17 62.0 0.0 5.8e-17 61.6 0.0 1.2 1 0 0 1 1 1 1 Paired amphipathic helix repeat SLT PF01464.20 ORY19532.1 - 0.00024 20.7 0.0 0.0028 17.3 0.0 2.1 1 1 0 1 1 1 1 Transglycosylase SLT domain Lysozyme_like PF13702.6 ORY19532.1 - 0.0066 16.2 0.4 0.015 15.0 0.4 1.5 1 1 0 1 1 1 1 Lysozyme-like PTR2 PF00854.21 ORY19533.1 - 9.5e-76 255.2 7.4 1.3e-75 254.7 7.4 1.2 1 0 0 1 1 1 1 POT family ADH_N PF08240.12 ORY19534.1 - 2.2e-28 98.3 1.3 3.4e-28 97.7 1.3 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORY19534.1 - 2.4e-26 92.2 0.0 3.9e-26 91.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 ORY19534.1 - 1.3e-09 37.9 0.1 1.8e-09 37.4 0.1 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 ORY19534.1 - 8.3e-08 33.4 0.0 1.4e-07 32.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_7 PF13241.6 ORY19534.1 - 0.005 17.3 0.0 0.0083 16.5 0.0 1.3 1 0 0 1 1 1 1 Putative NAD(P)-binding Sacchrp_dh_NADP PF03435.18 ORY19534.1 - 0.011 15.9 0.0 0.021 15.1 0.0 1.4 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain 3A PF00803.18 ORY19534.1 - 0.03 13.6 0.0 0.044 13.1 0.0 1.2 1 0 0 1 1 1 0 3A/RNA2 movement protein family 2-Hacid_dh_C PF02826.19 ORY19534.1 - 0.088 12.2 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain STAG PF08514.11 ORY19536.1 - 2.7e-30 104.6 3.1 4.6e-30 103.8 0.0 2.8 2 0 0 2 2 2 1 STAG domain HEAT_2 PF13646.6 ORY19536.1 - 1.2e-06 28.8 0.0 0.00034 20.9 0.0 3.0 1 1 1 2 2 2 2 HEAT repeats Cnd3 PF12719.7 ORY19536.1 - 0.011 15.0 0.2 0.94 8.6 0.0 3.0 3 0 0 3 3 3 0 Nuclear condensing complex subunits, C-term domain HEAT PF02985.22 ORY19536.1 - 0.015 15.5 0.1 72 4.0 0.0 4.7 4 0 0 4 4 4 0 HEAT repeat GIT1_C PF12205.8 ORY19537.1 - 0.0089 16.1 0.3 0.016 15.3 0.3 1.3 1 0 0 1 1 1 1 G protein-coupled receptor kinase-interacting protein 1 C term TSC22 PF01166.18 ORY19537.1 - 0.028 14.7 2.9 0.4 11.0 0.6 2.6 2 0 0 2 2 2 0 TSC-22/dip/bun family PRKG1_interact PF15898.5 ORY19537.1 - 0.67 10.9 6.8 1.9 9.4 6.8 1.8 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain AIG1 PF04548.16 ORY19538.1 - 1.6e-08 34.2 0.1 2.5e-08 33.5 0.1 1.3 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.23 ORY19538.1 - 2.6e-07 30.8 2.5 0.0027 17.8 0.2 3.1 2 1 1 3 3 3 2 Dynamin family MMR_HSR1 PF01926.23 ORY19538.1 - 1.4e-06 28.3 0.0 2.9e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ORY19538.1 - 0.0073 16.2 0.2 0.028 14.3 0.2 1.9 1 1 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 ORY19538.1 - 0.009 16.3 0.0 0.025 14.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain Septin PF00735.18 ORY19538.1 - 0.0094 15.3 0.3 0.053 12.8 0.0 2.3 2 1 0 2 2 2 1 Septin Viral_helicase1 PF01443.18 ORY19538.1 - 0.093 12.5 0.1 0.15 11.8 0.1 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.27 ORY19538.1 - 0.12 12.9 0.2 0.36 11.4 0.0 1.9 2 1 0 2 2 2 0 ABC transporter IIGP PF05049.13 ORY19538.1 - 0.14 11.1 0.1 0.24 10.4 0.1 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) DUF1640 PF07798.11 ORY19538.1 - 0.19 11.7 3.0 0.31 11.1 3.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) Gly_reductase PF09338.11 ORY19538.1 - 0.2 10.0 0.1 0.28 9.5 0.1 1.2 1 0 0 1 1 1 0 Glycine/sarcosine/betaine reductase component B subunits AAA_33 PF13671.6 ORY19538.1 - 0.4 10.8 1.7 1 9.5 0.2 2.1 2 0 0 2 2 2 0 AAA domain HSP70 PF00012.20 ORY19539.1 - 4e-15 55.1 0.4 1.9e-14 52.8 0.4 1.8 1 1 0 1 1 1 1 Hsp70 protein SKG6 PF08693.10 ORY19540.1 - 0.034 13.6 0.6 0.071 12.5 0.6 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain SOG2 PF10428.9 ORY19540.1 - 0.22 10.7 3.9 0.26 10.5 3.9 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DUF3176 PF11374.8 ORY19541.1 - 1.5e-11 44.4 1.0 1.5e-11 44.4 1.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) HET PF06985.11 ORY19543.1 - 1.7e-15 57.7 0.0 1.7e-15 57.6 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) tify PF06200.14 ORY19543.1 - 0.012 14.9 0.1 0.027 13.8 0.1 1.6 1 0 0 1 1 1 0 tify domain MarR_2 PF12802.7 ORY19543.1 - 0.069 13.0 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 MarR family Pol_alpha_B_N PF08418.10 ORY19544.1 - 1.3e-79 267.6 0.0 1.9e-79 267.1 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.16 ORY19544.1 - 1.2e-32 113.0 0.1 1.8e-32 112.4 0.1 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B LTV PF04180.14 ORY19544.1 - 0.11 12.2 0.1 0.17 11.6 0.1 1.2 1 0 0 1 1 1 0 Low temperature viability protein Ribosomal_S14 PF00253.21 ORY19546.1 - 5.6e-13 48.4 3.3 6e-13 48.3 3.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e DUF4428 PF14471.6 ORY19546.1 - 0.028 14.3 0.7 0.035 14.0 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) Fungal_trans PF04082.18 ORY19547.1 - 7.2e-13 48.2 4.3 1e-12 47.7 1.4 2.3 2 0 0 2 2 2 1 Fungal specific transcription factor domain Pox_A_type_inc PF04508.12 ORY19547.1 - 0.00036 20.3 5.2 0.00085 19.1 5.2 1.7 1 0 0 1 1 1 1 Viral A-type inclusion protein repeat Zn_clus PF00172.18 ORY19547.1 - 0.00061 19.9 11.9 0.00061 19.9 11.9 2.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GFA PF04828.14 ORY19548.1 - 8.5e-17 61.3 0.1 1.3e-16 60.6 0.1 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zf-NADH-PPase PF09297.11 ORY19548.1 - 0.014 15.1 0.2 0.014 15.1 0.2 2.4 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain Nudix_N_2 PF14803.6 ORY19548.1 - 0.15 12.0 0.2 0.15 12.0 0.2 2.6 2 1 0 2 2 2 0 Nudix N-terminal Nop10p PF04135.12 ORY19548.1 - 0.39 10.8 0.1 0.39 10.8 0.1 1.9 3 0 0 3 3 3 0 Nucleolar RNA-binding protein, Nop10p family Apc13p PF05839.11 ORY19549.1 - 3.7e-30 103.9 0.1 4.2e-30 103.8 0.1 1.0 1 0 0 1 1 1 1 Apc13p protein IF-2B PF01008.17 ORY19550.1 - 2.7e-75 253.2 0.0 3.5e-75 252.8 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family DeoRC PF00455.22 ORY19550.1 - 0.038 13.9 1.1 7.3 6.5 0.1 2.4 2 0 0 2 2 2 0 DeoR C terminal sensor domain Med13_C PF06333.12 ORY19550.1 - 0.15 11.3 0.9 0.22 10.8 0.9 1.2 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain IHABP4_N PF16174.5 ORY19550.1 - 3.5 8.2 20.9 3.1 8.4 19.5 1.6 1 1 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal Ndc1_Nup PF09531.10 ORY19550.1 - 6.2 5.4 6.6 8.2 5.0 6.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RCC1_2 PF13540.6 ORY19551.1 - 5e-10 38.9 18.1 2.5e-06 27.1 0.1 5.8 7 0 0 7 7 7 3 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 ORY19551.1 - 1.8e-09 38.1 6.1 6.1e-07 30.0 0.1 4.9 6 0 0 6 6 6 2 Regulator of chromosome condensation (RCC1) repeat F-box-like PF12937.7 ORY19551.1 - 0.00011 22.1 0.5 0.00021 21.1 0.5 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY19551.1 - 0.0036 17.2 0.2 0.0099 15.7 0.0 1.8 2 0 0 2 2 2 1 F-box domain Complex1_LYR PF05347.15 ORY19551.1 - 0.18 11.9 0.1 18 5.5 0.1 2.4 2 0 0 2 2 2 0 Complex 1 protein (LYR family) Abhydrolase_6 PF12697.7 ORY19555.1 - 1.6e-06 28.9 0.0 1.8e-06 28.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ORY19555.1 - 0.00053 19.7 0.0 0.00073 19.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF676 PF05057.14 ORY19555.1 - 0.0025 17.4 0.0 0.0035 16.9 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) UPF0565 PF10561.9 ORY19555.1 - 0.0054 16.0 0.1 0.011 15.0 0.0 1.5 2 0 0 2 2 2 1 Uncharacterised protein family UPF0565 Cutinase PF01083.22 ORY19555.1 - 0.0073 16.3 0.0 0.024 14.6 0.0 1.8 1 1 0 1 1 1 1 Cutinase PGAP1 PF07819.13 ORY19555.1 - 0.0096 15.7 0.0 0.02 14.6 0.0 1.5 2 0 0 2 2 2 1 PGAP1-like protein LCAT PF02450.15 ORY19555.1 - 0.011 15.0 0.0 0.015 14.5 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Abhydrolase_9 PF10081.9 ORY19555.1 - 0.085 11.9 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta-hydrolase family Hydrolase_4 PF12146.8 ORY19555.1 - 0.11 11.7 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF3089 PF11288.8 ORY19555.1 - 0.2 11.2 0.0 0.37 10.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) NB-ARC PF00931.22 ORY19556.1 - 1.4e-08 34.3 0.0 5.1e-08 32.4 0.0 2.0 1 1 0 1 1 1 1 NB-ARC domain TPR_12 PF13424.6 ORY19556.1 - 5.9e-06 26.5 2.6 0.073 13.4 0.2 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 ORY19556.1 - 0.00032 20.5 7.3 0.25 11.3 0.5 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat AAA_16 PF13191.6 ORY19556.1 - 0.0009 19.7 0.3 0.0039 17.6 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 ORY19556.1 - 0.0016 18.4 0.0 0.0036 17.2 0.0 1.7 1 0 0 1 1 1 1 NACHT domain TPR_19 PF14559.6 ORY19556.1 - 0.0037 17.7 2.6 0.12 13.0 0.0 4.2 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 ORY19556.1 - 0.0089 16.6 0.2 9 7.2 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat AAA_22 PF13401.6 ORY19556.1 - 0.053 13.8 0.1 0.31 11.3 0.0 2.3 3 0 0 3 3 3 0 AAA domain ATPase_2 PF01637.18 ORY19556.1 - 0.12 12.3 0.0 0.31 10.9 0.0 1.7 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Fungal_trans PF04082.18 ORY19557.1 - 4.3e-13 48.9 0.2 8.7e-13 47.9 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY19557.1 - 6.1e-09 35.9 12.5 1.4e-08 34.7 12.5 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 ORY19558.1 - 1.4e-28 99.8 75.3 1e-21 77.3 50.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY19558.1 - 4.7e-06 25.7 41.4 0.0058 15.5 15.2 3.1 2 1 1 3 3 3 3 Sugar (and other) transporter LDB19 PF13002.7 ORY19559.1 - 1.1e-53 181.9 0.4 2e-53 181.0 0.4 1.4 1 0 0 1 1 1 1 Arrestin_N terminal like Arrestin_N PF00339.29 ORY19559.1 - 2.3e-05 24.5 0.0 4.3e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Spo0M PF07070.11 ORY19559.1 - 0.005 16.4 0.0 0.0079 15.8 0.0 1.2 1 0 0 1 1 1 1 SpoOM protein DUF4078 PF13300.6 ORY19561.1 - 0.1 12.9 2.9 0.21 12.0 2.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4078) KRE1 PF17056.5 ORY19562.1 - 0.0014 18.3 3.7 0.0024 17.6 3.7 1.3 1 0 0 1 1 1 1 Killer toxin-resistance protein 1 Glyco_hydro_16 PF00722.21 ORY19563.1 - 1.8e-20 73.1 0.8 3.2e-20 72.3 0.8 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 RasGEF PF00617.19 ORY19564.1 - 4e-60 203.1 0.6 7.9e-60 202.1 0.6 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 ORY19564.1 - 1.5e-27 95.9 0.1 3.1e-27 94.9 0.1 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.28 ORY19564.1 - 1.6e-15 56.4 0.1 3.5e-15 55.3 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 ORY19564.1 - 3.3e-14 52.5 0.1 8.3e-14 51.2 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 ORY19564.1 - 1.3e-12 47.2 0.1 2.5e-12 46.3 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.26 ORY19564.1 - 0.00019 21.4 0.0 0.0004 20.4 0.0 1.6 1 0 0 1 1 1 1 WW domain CobT PF06213.12 ORY19564.1 - 0.38 10.1 0.0 0.38 10.1 0.0 2.3 3 0 0 3 3 3 0 Cobalamin biosynthesis protein CobT Fungal_trans PF04082.18 ORY19567.1 - 1.9e-15 56.6 1.6 2.9e-15 56.0 1.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.6 ORY19567.1 - 8.4e-07 29.1 14.4 7.9e-05 22.9 5.5 2.9 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 ORY19567.1 - 0.013 15.9 18.8 0.041 14.4 5.3 3.3 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_3rep PF18868.1 ORY19567.1 - 0.045 14.4 1.0 0.66 10.6 0.4 2.5 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_4 PF13894.6 ORY19567.1 - 0.28 12.2 19.6 0.28 12.2 4.1 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORY19567.1 - 6.7 7.1 8.8 1.4 9.3 3.7 2.6 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Ribosomal_L7Ae PF01248.26 ORY19568.1 - 4.1e-21 74.5 5.2 1.1e-19 70.0 5.2 2.5 1 1 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family SRP14 PF02290.15 ORY19568.1 - 1.8 9.0 11.1 0.072 13.5 0.8 2.7 2 1 0 2 2 2 0 Signal recognition particle 14kD protein CDC14 PF08045.11 ORY19570.1 - 1e-122 408.7 0.0 1.2e-122 408.5 0.0 1.0 1 0 0 1 1 1 1 Cell division control protein 14, SIN component TIP39 PF14980.6 ORY19570.1 - 0.15 12.0 0.0 6.3 6.8 0.0 2.8 2 0 0 2 2 2 0 TIP39 peptide PAP2_3 PF14378.6 ORY19571.1 - 9.4e-34 116.8 19.3 2.5e-17 63.2 0.1 3.5 3 0 0 3 3 3 3 PAP2 superfamily PAP2 PF01569.21 ORY19571.1 - 0.01 15.6 0.6 0.01 15.6 0.6 2.4 2 1 0 2 2 2 0 PAP2 superfamily SprT-like PF10263.9 ORY19572.1 - 1.3e-08 34.7 0.0 2.2e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 SprT-like family Mpv17_PMP22 PF04117.12 ORY19573.1 - 5e-13 49.1 2.1 2.1e-12 47.1 1.6 2.0 2 0 0 2 2 2 1 Mpv17 / PMP22 family Serinc PF03348.15 ORY19573.1 - 0.059 12.3 3.0 0.085 11.8 3.0 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) NADH_oxidored PF08040.11 ORY19573.1 - 0.098 12.4 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 MNLL subunit C1_2 PF03107.16 ORY19574.1 - 0.065 13.6 0.4 0.065 13.6 0.4 2.0 2 0 0 2 2 2 0 C1 domain Bestrophin PF01062.21 ORY19575.1 - 1.7e-54 185.2 0.0 2e-54 185.0 0.0 1.0 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Med18 PF09637.10 ORY19576.1 - 0.067 13.0 0.0 0.088 12.6 0.0 1.2 1 0 0 1 1 1 0 Med18 protein FHA PF00498.26 ORY19577.1 - 1.3e-15 57.5 0.0 2.2e-15 56.7 0.0 1.4 1 0 0 1 1 1 1 FHA domain zf-RING_11 PF17123.5 ORY19577.1 - 5.3e-13 48.5 6.9 9.7e-13 47.6 6.9 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 ORY19577.1 - 2.5e-07 30.9 9.2 5.5e-07 29.8 9.2 1.6 1 0 0 1 1 1 1 Ring finger domain Yop-YscD_cpl PF16697.5 ORY19577.1 - 5.5e-05 23.4 0.0 0.00011 22.4 0.0 1.4 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain zf-C3HC4_2 PF13923.6 ORY19577.1 - 0.0046 16.8 8.5 0.01 15.7 8.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORY19577.1 - 0.0059 16.5 5.0 0.011 15.7 5.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 ORY19577.1 - 0.006 16.4 7.9 0.012 15.4 7.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 ORY19577.1 - 0.012 15.5 4.3 0.022 14.6 4.3 1.5 1 0 0 1 1 1 0 PHD-finger zf-rbx1 PF12678.7 ORY19577.1 - 0.034 14.4 7.9 0.12 12.7 7.9 1.9 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 ORY19577.1 - 0.038 14.1 2.0 0.078 13.0 2.0 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 ORY19577.1 - 0.19 11.8 8.4 0.46 10.6 8.4 1.7 1 0 0 1 1 1 0 RING-type zinc-finger Vps39_2 PF10367.9 ORY19577.1 - 0.32 11.5 3.4 0.6 10.6 3.4 1.4 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 Zn_ribbon_17 PF17120.5 ORY19577.1 - 3.2 7.5 8.9 3.7 7.3 7.1 2.0 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type Peptidase_M16 PF00675.20 ORY19578.1 - 6.7e-41 139.7 0.0 2.2e-40 138.0 0.0 1.8 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 ORY19578.1 - 9.1e-34 117.1 0.0 2.6e-18 66.7 0.0 2.5 2 0 0 2 2 2 2 Peptidase M16 inactive domain TRPM_tetra PF16519.5 ORY19578.1 - 2.3 8.4 4.2 9.7 6.4 0.6 2.4 2 0 0 2 2 2 0 Tetramerisation domain of TRPM PGP_phosphatase PF09419.10 ORY19579.1 - 1.9e-64 216.3 0.0 2.2e-64 216.1 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.6 ORY19579.1 - 0.0036 17.3 0.0 0.008 16.2 0.0 1.5 1 1 0 1 1 1 1 HAD-hyrolase-like LSM PF01423.22 ORY19580.1 - 2.1e-15 56.1 0.1 2.8e-15 55.8 0.1 1.2 1 0 0 1 1 1 1 LSM domain Adaptin_binding PF10199.9 ORY19581.1 - 3.8e-11 43.6 6.1 9.4e-11 42.4 6.1 1.7 1 1 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 Methyltransf_23 PF13489.6 ORY19582.1 - 2.5e-16 59.9 0.0 3.4e-16 59.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY19582.1 - 5.9e-15 55.8 0.0 1.1e-14 54.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY19582.1 - 9.4e-15 55.1 0.2 1.9e-13 50.9 0.1 2.4 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY19582.1 - 2.3e-14 53.8 0.1 5e-13 49.5 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY19582.1 - 7.9e-14 51.7 0.0 2.3e-13 50.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 ORY19582.1 - 0.00024 21.1 0.0 0.00035 20.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORY19582.1 - 0.0006 19.2 0.0 0.0062 15.9 0.0 2.1 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family NodS PF05401.11 ORY19582.1 - 0.001 18.7 0.0 0.0022 17.7 0.0 1.6 2 0 0 2 2 2 1 Nodulation protein S (NodS) Methyltransf_4 PF02390.17 ORY19582.1 - 0.012 15.0 0.0 0.12 11.9 0.0 2.1 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_9 PF08003.11 ORY19582.1 - 0.036 13.0 0.0 0.25 10.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) MTS PF05175.14 ORY19582.1 - 0.074 12.6 0.1 0.18 11.4 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_16 PF10294.9 ORY19582.1 - 0.075 12.8 0.0 0.16 11.7 0.0 1.5 2 0 0 2 2 2 0 Lysine methyltransferase TPMT PF05724.11 ORY19582.1 - 0.078 12.6 0.0 0.18 11.5 0.0 1.8 1 1 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) RrnaAD PF00398.20 ORY19582.1 - 0.079 12.0 0.0 0.094 11.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase PCMT PF01135.19 ORY19582.1 - 0.084 12.6 0.0 0.31 10.8 0.0 1.9 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Fungal_lectin PF07938.12 ORY19585.1 - 2.3e-10 40.4 6.3 1.1e-09 38.2 5.2 2.3 1 1 1 2 2 2 2 Fungal fucose-specific lectin EF-hand_1 PF00036.32 ORY19586.1 - 0.0013 18.1 5.7 0.47 10.1 0.0 3.3 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 ORY19586.1 - 0.013 15.4 2.8 5.6 7.2 0.1 3.2 3 0 0 3 3 3 0 EF-hand domain EF-hand_5 PF13202.6 ORY19586.1 - 0.15 11.6 7.8 11 5.8 0.2 3.4 3 0 0 3 3 3 0 EF hand Excalibur PF05901.11 ORY19586.1 - 1 10.0 4.9 10 6.9 0.1 2.8 3 0 0 3 3 3 0 Excalibur calcium-binding domain Glyco_hydro_31 PF01055.26 ORY19588.1 - 6.8e-165 549.5 1.6 9e-165 549.1 1.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 ORY19588.1 - 1.3e-40 138.2 0.3 2.6e-40 137.2 0.3 1.5 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 ORY19588.1 - 4.1e-14 52.7 0.8 4.1e-14 52.7 0.8 2.1 2 0 0 2 2 2 1 Galactose mutarotase-like Prp19 PF08606.11 ORY19589.1 - 4.8e-33 113.0 3.3 1e-32 111.9 3.3 1.6 1 0 0 1 1 1 1 Prp19/Pso4-like WD40 PF00400.32 ORY19589.1 - 9.3e-16 57.9 1.3 0.0013 19.5 0.0 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY19589.1 - 2.9e-12 46.7 0.0 0.0093 16.3 0.0 5.3 1 1 5 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ORY19589.1 - 4.7e-06 26.6 0.3 0.02 14.8 0.0 3.6 1 1 3 4 4 4 1 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 ORY19589.1 - 0.0001 21.7 0.0 0.0051 16.2 0.0 2.2 1 1 1 2 2 2 1 WD40-like domain Cytochrom_D1 PF02239.16 ORY19589.1 - 0.00047 18.8 0.0 0.019 13.5 0.0 2.4 2 1 0 2 2 2 1 Cytochrome D1 heme domain U-box PF04564.15 ORY19589.1 - 0.0051 17.0 0.0 0.011 15.9 0.0 1.5 1 0 0 1 1 1 1 U-box domain V_ATPase_I_N PF18670.1 ORY19589.1 - 0.027 14.9 0.1 0.052 13.9 0.1 1.4 1 0 0 1 1 1 0 V-type ATPase subunit I, N-terminal domain zf-Nse PF11789.8 ORY19589.1 - 0.1 12.4 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Frtz PF11768.8 ORY19589.1 - 0.1 10.9 0.0 4.4 5.5 0.0 2.1 1 1 1 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz Mcl1_mid PF12341.8 ORY19589.1 - 0.1 11.9 0.3 0.6 9.4 0.2 2.2 1 1 0 1 1 1 0 Minichromosome loss protein, Mcl1, middle region zf-RING_5 PF14634.6 ORY19591.1 - 0.00041 20.3 3.5 0.00066 19.6 3.5 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 ORY19591.1 - 0.0093 16.0 1.3 0.018 15.0 1.3 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 ORY19591.1 - 0.012 16.0 4.0 0.024 15.0 4.0 1.5 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4 PF00097.25 ORY19591.1 - 0.06 13.2 3.4 0.12 12.3 3.4 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 ORY19591.1 - 0.22 11.4 6.1 0.6 10.0 6.1 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 ORY19591.1 - 0.35 11.1 2.7 0.59 10.3 0.2 2.2 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 ORY19591.1 - 1 9.3 7.0 0.61 10.0 2.0 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 ORY19591.1 - 1.1 9.2 7.8 3.4 7.6 7.9 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PTPLA PF04387.14 ORY19592.1 - 3.7e-56 189.4 11.3 5.5e-56 188.8 11.3 1.3 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA Asp PF00026.23 ORY19593.1 - 9.8e-13 48.2 0.1 1.7e-12 47.4 0.1 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease SKG6 PF08693.10 ORY19593.1 - 0.00017 21.0 0.5 0.00035 19.9 0.5 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain VSP PF03302.13 ORY19593.1 - 0.062 12.2 0.1 0.096 11.5 0.1 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein TMEM51 PF15345.6 ORY19593.1 - 0.096 12.5 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 BatA PF07584.11 ORY19593.1 - 0.098 13.0 0.1 0.26 11.7 0.1 1.6 1 0 0 1 1 1 0 Aerotolerance regulator N-terminal Stevor PF17410.2 ORY19593.1 - 0.22 11.0 0.0 0.43 10.1 0.0 1.4 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame Gram_pos_anchor PF00746.21 ORY19593.1 - 0.31 11.0 4.2 15 5.6 3.6 3.3 2 1 0 2 2 2 0 LPXTG cell wall anchor motif XhlA PF10779.9 ORY19594.1 - 0.35 11.1 0.6 0.58 10.4 0.6 1.3 1 0 0 1 1 1 0 Haemolysin XhlA CMD PF02627.20 ORY19595.1 - 9.2e-05 22.4 0.1 0.0055 16.7 0.0 2.2 2 0 0 2 2 2 2 Carboxymuconolactone decarboxylase family Methyltransf_34 PF11312.8 ORY19596.1 - 1.4e-102 343.1 0.0 1.6e-102 342.9 0.0 1.0 1 0 0 1 1 1 1 Putative SAM-dependent methyltransferase AA_synth PF06684.11 ORY19596.1 - 0.1 12.2 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Amino acid synthesis Sulfate_transp PF00916.20 ORY19597.1 - 0.035 12.8 0.0 0.042 12.6 0.0 1.1 1 0 0 1 1 1 0 Sulfate permease family HET PF06985.11 ORY19600.1 - 9.1e-35 120.2 5.0 2.6e-34 118.7 5.0 1.6 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Transposase_1 PF01359.18 ORY19600.1 - 0.11 12.3 0.1 0.18 11.7 0.1 1.3 1 0 0 1 1 1 0 Transposase (partial DDE domain) PalH PF08733.10 ORY19601.1 - 4.7e-117 390.7 0.0 5.6e-117 390.4 0.0 1.1 1 0 0 1 1 1 1 PalH/RIM21 GIIM PF08388.11 ORY19601.1 - 8.5 6.5 7.5 0.2 11.8 0.3 2.0 2 0 0 2 2 2 0 Group II intron, maturase-specific domain PX PF00787.24 ORY19602.1 - 3.1e-17 62.6 0.1 6.8e-17 61.5 0.1 1.6 1 0 0 1 1 1 1 PX domain UBA_4 PF14555.6 ORY19603.1 - 3.7e-10 39.4 0.1 4.8e-10 39.1 0.1 1.2 1 0 0 1 1 1 1 UBA-like domain Parvo_coat_N PF08398.10 ORY19603.1 - 0.0097 16.0 1.0 0.096 12.9 0.0 2.2 1 1 1 2 2 2 1 Parvovirus coat protein VP1 HTH_54 PF18607.1 ORY19603.1 - 0.12 12.5 2.7 0.38 10.8 0.2 2.0 1 1 1 2 2 2 0 ParA helix turn helix domain DUF5421 PF17458.2 ORY19603.1 - 0.15 11.4 4.4 0.16 11.3 4.4 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5421) Cullin_binding PF03556.15 ORY19604.1 - 2.9e-29 101.9 11.3 4.6e-29 101.3 11.3 1.3 1 0 0 1 1 1 1 Cullin binding Ribosomal_L32e PF01655.18 ORY19605.1 - 9.3e-50 167.6 0.8 9.3e-50 167.6 0.8 1.4 2 0 0 2 2 2 1 Ribosomal protein L32 DUF3450 PF11932.8 ORY19608.1 - 0.00065 19.1 1.5 0.0013 18.1 1.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) UPF0242 PF06785.11 ORY19608.1 - 0.024 14.8 1.0 0.052 13.7 1.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus vATP-synt_E PF01991.18 ORY19608.1 - 0.044 13.2 0.1 0.044 13.2 0.1 1.7 2 0 0 2 2 2 0 ATP synthase (E/31 kDa) subunit DHR10 PF18595.1 ORY19608.1 - 0.11 12.6 8.2 0.037 14.1 4.6 2.0 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain APG6_N PF17675.1 ORY19608.1 - 0.2 12.2 8.2 0.056 14.0 4.4 2.1 2 0 0 2 2 2 0 Apg6 coiled-coil region Jnk-SapK_ap_N PF09744.9 ORY19608.1 - 1.8 8.8 10.8 0.45 10.7 3.3 2.7 3 0 0 3 3 3 0 JNK_SAPK-associated protein-1 DUF737 PF05300.11 ORY19608.1 - 9.3 6.5 10.6 2.8e+02 1.7 0.0 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF737) Med3 PF11593.8 ORY19609.1 - 0.041 13.1 1.7 0.058 12.6 1.7 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal BRK PF07533.16 ORY19609.1 - 0.096 12.3 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 BRK domain Dynamin_M PF01031.20 ORY19613.1 - 1.7e-45 155.5 0.0 2.5e-45 154.9 0.0 1.3 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 ORY19613.1 - 2.9e-27 95.8 0.0 9.8e-27 94.0 0.0 1.9 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 ORY19613.1 - 2.7e-06 27.4 0.1 0.00015 21.8 0.0 3.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase GED PF02212.18 ORY19613.1 - 1.7e-05 24.9 0.0 8e-05 22.7 0.0 2.3 2 0 0 2 2 2 1 Dynamin GTPase effector domain FeoB_N PF02421.18 ORY19613.1 - 0.00091 18.8 0.0 0.62 9.6 0.0 2.4 2 0 0 2 2 2 2 Ferrous iron transport protein B DUF1967 PF09269.11 ORY19613.1 - 0.0071 16.3 3.0 1.3 9.0 0.3 3.5 3 0 0 3 3 3 1 Domain of unknown function (DUF1967) AAA_21 PF13304.6 ORY19613.1 - 0.028 14.2 0.0 0.066 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran PF00005.27 ORY19613.1 - 0.055 14.0 0.0 0.29 11.6 0.0 2.2 2 0 0 2 2 2 0 ABC transporter Roc PF08477.13 ORY19613.1 - 0.075 13.3 0.0 0.75 10.0 0.0 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase ArAE_2_N PF10337.9 ORY19614.1 - 1.9e-45 155.8 35.5 1.3e-40 139.8 0.8 5.2 3 2 1 4 4 4 3 Putative ER transporter, 6TM, N-terminal FUSC_2 PF13515.6 ORY19614.1 - 1.3e-17 64.1 16.2 1.3e-17 64.1 16.2 2.6 2 0 0 2 2 2 1 Fusaric acid resistance protein-like ArAE_2 PF10334.9 ORY19614.1 - 1e-10 41.9 0.0 2.9e-10 40.4 0.0 1.8 2 0 0 2 2 2 1 Aromatic acid exporter family member 2 ArAE_1 PF06081.11 ORY19614.1 - 0.0038 17.4 8.8 0.0038 17.4 8.8 2.7 2 0 0 2 2 2 1 Aromatic acid exporter family member 1 Utp8 PF10395.9 ORY19615.1 - 3.8e-15 55.5 0.6 3.8e-13 48.8 1.5 3.1 2 1 0 2 2 2 1 Utp8 family Rad17 PF03215.15 ORY19616.1 - 8.8e-10 38.8 0.0 2.3e-05 24.4 0.0 3.2 3 0 0 3 3 3 2 Rad17 P-loop domain AAA PF00004.29 ORY19616.1 - 2.5e-07 31.2 0.0 2.4e-06 28.0 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 ORY19616.1 - 0.00022 21.7 0.1 0.00063 20.2 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 ORY19616.1 - 0.0042 17.6 0.0 0.014 15.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 ORY19616.1 - 0.0079 15.7 0.0 0.015 14.8 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region TsaE PF02367.17 ORY19616.1 - 0.029 14.4 0.0 0.055 13.5 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 ORY19616.1 - 0.068 13.3 0.0 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 ORY19616.1 - 0.08 12.9 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 ORY19616.1 - 0.095 13.0 0.1 0.39 11.0 0.1 2.1 2 1 0 2 2 2 0 AAA domain AAA_14 PF13173.6 ORY19616.1 - 0.15 12.1 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 ORY19616.1 - 0.19 12.1 0.0 0.49 10.8 0.0 1.7 1 0 0 1 1 1 0 RNA helicase ALGX PF16822.5 ORY19616.1 - 0.36 10.5 2.6 1.7 8.2 0.5 2.3 2 0 0 2 2 2 0 SGNH hydrolase-like domain, acetyltransferase AlgX Alb1 PF09135.11 ORY19617.1 - 1.4e-15 58.0 2.4 2.5e-15 57.2 2.4 1.3 1 0 0 1 1 1 1 Alb1 UCH PF00443.29 ORY19618.1 - 1.4e-30 106.6 0.0 3.8e-30 105.2 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 ORY19618.1 - 1.4e-10 41.3 0.1 3e-10 40.2 0.1 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ALIX_LYPXL_bnd PF13949.6 ORY19618.1 - 0.025 13.9 0.5 0.05 12.9 0.5 1.5 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV PHM7_cyt PF14703.6 ORY19618.1 - 0.11 12.7 0.1 0.29 11.4 0.1 1.7 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter HAGH_C PF16123.5 ORY19622.1 - 1.8e-21 76.4 0.3 3.3e-21 75.6 0.3 1.4 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 ORY19622.1 - 4.7e-16 59.4 3.1 5.1e-14 52.7 3.1 2.2 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Alpha_L_fucos PF01120.17 ORY19623.1 - 2.5e-77 260.7 8.9 3.4e-77 260.2 8.9 1.1 1 0 0 1 1 1 1 Alpha-L-fucosidase KOW PF00467.29 ORY19623.1 - 0.14 12.1 0.6 0.78 9.8 0.5 2.4 2 0 0 2 2 2 0 KOW motif DUF2235 PF09994.9 ORY19624.1 - 5.5e-77 258.9 0.0 6.4e-77 258.7 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Palm_thioest PF02089.15 ORY19624.1 - 0.0074 16.2 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 Palmitoyl protein thioesterase HALZ PF02183.18 ORY19624.1 - 0.23 11.7 0.4 0.45 10.8 0.4 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper zf_CCCH_4 PF18345.1 ORY19626.1 - 0.04 14.0 1.0 0.04 14.0 1.0 4.5 4 0 0 4 4 4 0 Zinc finger domain Torus PF16131.5 ORY19626.1 - 2.3 9.0 7.7 1.1 10.0 0.2 2.9 2 1 1 3 3 3 0 Torus domain zf-CCCH PF00642.24 ORY19626.1 - 6.4 6.8 19.1 0.53 10.3 1.0 4.4 5 0 0 5 5 5 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) TRAP_alpha PF03896.16 ORY19627.1 - 0.0013 18.0 0.0 0.0021 17.3 0.0 1.2 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit DUF2206 PF09971.9 ORY19627.1 - 0.01 14.6 0.0 0.012 14.4 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2206) F-box-like PF12937.7 ORY19662.1 - 1.1e-05 25.2 0.0 1.9e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY19662.1 - 0.057 13.3 0.5 0.17 11.8 0.5 1.8 1 1 0 1 1 1 0 F-box domain WD40 PF00400.32 ORY19663.1 - 5.6e-26 90.3 11.3 9.2e-05 23.1 0.0 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY19663.1 - 6.3e-14 52.0 5.0 9.3e-05 22.7 0.2 4.0 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ORY19663.1 - 3e-08 33.8 0.1 0.036 13.9 0.0 3.2 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Peptidase_M18 PF02127.15 ORY19664.1 - 2.9e-172 573.3 0.0 3.5e-172 573.1 0.0 1.1 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 ORY19664.1 - 0.00061 18.9 0.4 0.2 10.7 0.1 3.4 2 1 1 3 3 3 2 M42 glutamyl aminopeptidase Hydrolase_6 PF13344.6 ORY19665.1 - 4.3e-31 107.0 0.0 8.2e-31 106.1 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ORY19665.1 - 6.1e-14 51.8 0.0 1.3e-13 50.8 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 ORY19665.1 - 6.3e-13 49.5 0.4 1.7e-05 25.2 0.0 3.0 2 1 1 3 3 3 3 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 ORY19665.1 - 2.2e-05 24.6 0.2 0.031 14.4 0.0 2.5 2 1 1 3 3 3 2 Haloacid dehalogenase-like hydrolase DNA_primase_lrg PF04104.14 ORY19666.1 - 1.2e-84 283.9 0.0 2.2e-84 283.0 0.0 1.4 2 0 0 2 2 2 1 Eukaryotic and archaeal DNA primase, large subunit zf-RING_2 PF13639.6 ORY19670.1 - 2.8e-12 46.7 4.8 4.4e-12 46.1 4.8 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 ORY19670.1 - 5.1e-09 35.8 3.6 8e-09 35.2 3.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORY19670.1 - 1.6e-08 34.2 2.3 2.5e-08 33.6 2.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 ORY19670.1 - 2.1e-08 33.8 1.9 2.1e-08 33.8 1.9 1.8 2 0 0 2 2 2 1 RING-like zinc finger zf-rbx1 PF12678.7 ORY19670.1 - 2.7e-08 33.9 2.8 5.3e-08 33.0 2.8 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain PA PF02225.22 ORY19670.1 - 2.2e-07 30.8 0.0 5.6e-07 29.5 0.0 1.7 1 0 0 1 1 1 1 PA domain zf-RING_5 PF14634.6 ORY19670.1 - 7.1e-07 29.1 1.7 1.1e-06 28.5 1.7 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 ORY19670.1 - 5.4e-06 26.3 1.3 1.6e-05 24.9 0.2 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 ORY19670.1 - 1.5e-05 24.7 2.8 2.2e-05 24.2 2.8 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 ORY19670.1 - 0.0018 18.3 0.5 0.0036 17.3 0.5 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 ORY19670.1 - 0.0085 15.9 2.8 0.015 15.2 2.8 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 ORY19670.1 - 0.023 14.3 2.6 0.043 13.5 2.6 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.6 ORY19670.1 - 0.22 11.7 3.7 0.46 10.7 3.7 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 ORY19670.1 - 0.24 11.6 1.8 0.59 10.4 1.8 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.7 ORY19670.1 - 0.57 10.3 2.2 1.1 9.5 2.1 1.6 1 1 0 1 1 1 0 RING-variant domain MIP PF00230.20 ORY19671.1 - 2.1e-50 171.5 14.1 2.7e-50 171.2 14.1 1.1 1 0 0 1 1 1 1 Major intrinsic protein p450 PF00067.22 ORY19673.1 - 2.7e-66 224.2 0.0 5.1e-66 223.3 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 DUF2270 PF10028.9 ORY19674.1 - 0.0093 15.5 0.0 0.048 13.2 0.0 2.1 2 0 0 2 2 2 1 Predicted integral membrane protein (DUF2270) Fungal_trans PF04082.18 ORY19674.1 - 0.091 11.8 0.1 0.13 11.3 0.1 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain Cyclase PF04199.13 ORY19675.1 - 8.1e-15 55.3 0.0 1e-14 54.9 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase Coq4 PF05019.13 ORY19678.1 - 1.2e-94 315.8 0.0 1.4e-94 315.6 0.0 1.0 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 SET PF00856.28 ORY19679.1 - 3.9e-15 56.6 0.0 6.4e-15 55.9 0.0 1.3 1 0 0 1 1 1 1 SET domain SAF PF08666.12 ORY19679.1 - 0.14 12.8 0.0 3.6 8.3 0.0 2.3 2 0 0 2 2 2 0 SAF domain ATP-sulfurylase PF01747.17 ORY19680.1 - 3.2e-88 294.7 0.0 4.7e-88 294.2 0.0 1.3 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.20 ORY19680.1 - 3.1e-57 192.9 0.0 4.6e-57 192.3 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.6 ORY19680.1 - 8e-52 175.1 0.0 1.4e-51 174.3 0.0 1.4 1 0 0 1 1 1 1 PUA-like domain PAPS_reduct PF01507.19 ORY19681.1 - 4.1e-44 150.7 0.0 5.3e-44 150.3 0.0 1.1 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family HTH_6 PF01418.17 ORY19682.1 - 0.0027 17.6 0.3 0.24 11.4 0.0 3.0 3 0 0 3 3 3 1 Helix-turn-helix domain, rpiR family RST PF12174.8 ORY19682.1 - 0.082 12.8 0.1 0.34 10.9 0.1 2.1 1 0 0 1 1 1 0 RCD1-SRO-TAF4 (RST) plant domain dsDNA_bind PF01984.20 ORY19684.1 - 1.1e-37 128.7 12.5 1.3e-37 128.4 12.5 1.1 1 0 0 1 1 1 1 Double-stranded DNA-binding domain UCMA PF17085.5 ORY19684.1 - 0.061 13.3 0.0 0.088 12.8 0.0 1.2 1 0 0 1 1 1 0 Unique cartilage matrix associated protein Sec2p PF06428.11 ORY19685.1 - 1.8e-28 98.3 16.8 1.8e-28 98.3 16.8 3.2 3 0 0 3 3 3 1 GDP/GTP exchange factor Sec2p Sec8_exocyst PF04048.14 ORY19685.1 - 0.095 12.6 10.4 1.7 8.5 2.2 2.5 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain Macoilin PF09726.9 ORY19685.1 - 2 6.9 28.8 0.0044 15.7 14.6 2.3 2 0 0 2 2 2 0 Macoilin family RraA-like PF03737.15 ORY19686.1 - 1.6e-32 112.8 0.0 2.2e-32 112.3 0.0 1.2 1 0 0 1 1 1 1 Aldolase/RraA Peptidase_M28 PF04389.17 ORY19687.1 - 3.5e-34 118.2 0.0 5e-34 117.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 ORY19687.1 - 7.6e-14 51.5 0.8 2.6e-13 49.8 0.8 1.9 2 0 0 2 2 2 1 PA domain Peptidase_M20 PF01546.28 ORY19687.1 - 0.0074 16.0 0.0 0.015 15.0 0.0 1.7 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Med8 PF10232.9 ORY19692.1 - 4.1e-12 46.2 1.0 6.8e-12 45.5 1.0 1.6 1 1 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 DUF4611 PF15387.6 ORY19692.1 - 0.14 12.3 4.9 0.073 13.3 2.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Methyltransf_PK PF05891.12 ORY19693.1 - 1.7e-81 272.9 0.0 2e-81 272.7 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.6 ORY19693.1 - 0.0019 18.8 0.0 0.0034 18.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CitG PF01874.16 ORY19693.1 - 0.15 11.7 0.0 0.22 11.2 0.0 1.2 1 0 0 1 1 1 0 ATP:dephospho-CoA triphosphoribosyl transferase Aldedh PF00171.22 ORY19694.1 - 1.3e-180 600.9 0.8 1.5e-180 600.7 0.8 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Metallophos PF00149.28 ORY19695.1 - 1.7e-35 123.4 0.1 2.7e-35 122.8 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 ORY19695.1 - 2.5e-16 59.8 0.0 4.7e-16 59.0 0.0 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Carb_anhydrase PF00194.21 ORY19697.1 - 6e-35 121.0 0.0 8.4e-35 120.5 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase WD40 PF00400.32 ORY19698.1 - 6e-12 45.9 4.5 6.5e-05 23.6 0.0 4.8 4 0 0 4 4 4 3 WD domain, G-beta repeat CTP_transf_like PF01467.26 ORY19699.1 - 0.00011 22.4 0.1 0.00056 20.1 0.1 2.0 1 1 0 1 1 1 1 Cytidylyltransferase-like F-box PF00646.33 ORY19700.1 - 0.013 15.4 0.3 0.64 10.0 0.3 2.7 2 0 0 2 2 2 0 F-box domain ADH_zinc_N PF00107.26 ORY19701.1 - 3.1e-29 101.6 3.0 5.3e-29 100.8 1.8 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ORY19701.1 - 6.9e-14 53.0 0.1 1.1e-13 52.4 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ORY19701.1 - 0.00083 19.2 0.3 0.0028 17.5 0.0 2.0 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Eno-Rase_NADH_b PF12242.8 ORY19701.1 - 0.1 12.3 1.6 0.19 11.5 1.6 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Spt5-NGN PF03439.13 ORY19702.1 - 1.5e-20 72.9 0.2 3.1e-20 71.9 0.2 1.6 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.8 ORY19702.1 - 3.1e-14 53.8 16.1 3.1e-14 53.8 16.1 3.4 2 1 1 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal CTD PF12815.7 ORY19702.1 - 3.3e-05 24.4 13.6 3.3e-05 24.4 13.6 5.0 1 1 1 2 2 2 1 Spt5 C-terminal nonapeptide repeat binding Spt4 KOW PF00467.29 ORY19702.1 - 0.00025 20.9 20.2 0.072 13.1 0.1 5.3 5 0 0 5 5 5 3 KOW motif NusG PF02357.19 ORY19702.1 - 0.0013 19.2 0.3 0.0067 16.9 0.2 2.0 2 0 0 2 2 2 1 Transcription termination factor nusG DUF3912 PF13051.6 ORY19702.1 - 0.0099 16.1 0.1 0.044 14.0 0.1 2.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3912) DUF1506 PF07405.11 ORY19702.1 - 0.15 12.3 0.0 0.29 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1506) Cornifin PF02389.15 ORY19702.1 - 0.4 10.9 7.7 0.81 9.9 7.7 1.4 1 0 0 1 1 1 0 Cornifin (SPRR) family Myosin_N PF02736.19 ORY19702.1 - 3 7.8 11.3 1 9.3 0.1 3.2 3 0 0 3 3 3 0 Myosin N-terminal SH3-like domain HSBP1 PF06825.12 ORY19704.1 - 0.0064 16.3 0.3 0.015 15.2 0.3 1.6 1 1 0 1 1 1 1 Heat shock factor binding protein 1 BLOC1_2 PF10046.9 ORY19704.1 - 0.04 14.2 0.0 0.064 13.6 0.0 1.4 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Filo_VP35 PF02097.15 ORY19704.1 - 0.048 12.7 0.0 0.048 12.7 0.0 1.1 1 0 0 1 1 1 0 Filoviridae VP35 Erythro-docking PF09277.11 ORY19704.1 - 0.17 11.8 0.1 0.43 10.5 0.0 1.6 1 1 1 2 2 2 0 Erythronolide synthase, docking MFS_1 PF07690.16 ORY19705.1 - 4.3e-22 78.5 34.6 4.3e-22 78.5 34.6 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY19705.1 - 7.8e-07 28.3 7.7 7.8e-07 28.3 7.7 2.5 1 1 1 3 3 3 1 Sugar (and other) transporter DUF1980 PF09323.10 ORY19705.1 - 0.026 14.5 2.0 0.026 14.4 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) S_4TM PF18159.1 ORY19705.1 - 9.1 5.5 5.7 0.63 9.3 0.2 1.9 2 0 0 2 2 2 0 SMODS-associating 4TM effector domain BPL_LplA_LipB PF03099.19 ORY19706.1 - 4.7e-10 39.5 0.0 7.3e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Rpp20 PF12328.8 ORY19707.1 - 6.3e-30 103.9 5.6 6.3e-30 103.9 5.6 2.3 3 0 0 3 3 3 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.21 ORY19707.1 - 1.3e-08 34.5 0.0 3.8e-08 33.0 0.0 1.8 1 1 0 1 1 1 1 Alba FHA PF00498.26 ORY19708.1 - 3.4e-17 62.6 0.1 7.4e-17 61.5 0.1 1.6 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 ORY19708.1 - 0.00025 21.3 0.0 0.00072 19.8 0.0 1.7 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain YhfZ_C PF14503.6 ORY19708.1 - 0.041 13.4 0.0 0.084 12.4 0.0 1.4 1 0 0 1 1 1 0 YhfZ C-terminal domain Macoilin PF09726.9 ORY19708.1 - 0.87 8.1 21.8 0.064 11.8 0.9 3.3 3 0 0 3 3 3 0 Macoilin family DUF4349 PF14257.6 ORY19708.1 - 2.1 7.7 6.1 4 6.8 1.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) Romo1 PF10247.9 ORY19709.1 - 1.6e-27 95.7 13.3 2.1e-27 95.3 13.3 1.2 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Tim17 PF02466.19 ORY19709.1 - 0.011 16.1 3.1 0.014 15.7 3.1 1.1 1 0 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family Form-deh_trans PF09163.11 ORY19709.1 - 4.4 7.2 5.7 25 4.7 0.3 2.4 2 0 0 2 2 2 0 Formate dehydrogenase N, transmembrane ERG4_ERG24 PF01222.17 ORY19711.1 - 9e-140 466.2 21.9 1e-139 466.0 21.9 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF4131 PF13567.6 ORY19711.1 - 0.049 13.3 1.4 0.12 12.1 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) IBR PF01485.21 ORY19712.1 - 1.8e-26 92.1 30.2 5.7e-12 45.7 8.5 4.2 3 1 1 4 4 4 4 IBR domain, a half RING-finger domain CCDC50_N PF15295.6 ORY19712.1 - 0.069 13.3 3.7 0.14 12.4 3.7 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 50 N-terminus zf-RING_14 PF17978.1 ORY19712.1 - 0.19 12.2 5.4 0.17 12.4 0.5 2.6 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain Desulfoferrod_N PF06397.12 ORY19712.1 - 0.33 10.6 5.8 0.18 11.4 1.0 2.5 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain zf-C3HC4_2 PF13923.6 ORY19712.1 - 3.3 7.6 16.1 1.1 9.2 1.5 3.9 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF678 PF05077.12 ORY19712.1 - 3.6 7.8 8.2 11 6.2 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF678) Peroxidase_2 PF01328.17 ORY19713.1 - 1.4e-16 61.6 3.0 9.8e-12 45.8 0.7 2.1 1 1 1 2 2 2 2 Peroxidase, family 2 DUF4603 PF15376.6 ORY19714.1 - 0.16 9.3 0.0 0.19 9.1 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) zf-C2H2_4 PF13894.6 ORY19716.1 - 1.4 9.9 8.2 3.7 8.6 0.5 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger AAA PF00004.29 ORY19717.1 - 6.8e-47 159.2 0.0 2.1e-41 141.4 0.0 3.0 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 ORY19717.1 - 3.4e-10 39.6 0.0 1.3e-09 37.7 0.0 2.0 1 0 0 1 1 1 1 AAA+ lid domain IstB_IS21 PF01695.17 ORY19717.1 - 7.5e-07 29.0 0.0 2.2e-06 27.5 0.0 1.7 2 0 0 2 2 1 1 IstB-like ATP binding protein AAA_16 PF13191.6 ORY19717.1 - 1.7e-06 28.5 0.0 3.1e-05 24.4 0.0 2.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_2 PF07724.14 ORY19717.1 - 1.2e-05 25.5 0.0 3.3e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Bromodomain PF00439.25 ORY19717.1 - 6.1e-05 23.0 0.7 0.00015 21.8 0.1 1.9 2 0 0 2 2 1 1 Bromodomain AAA_5 PF07728.14 ORY19717.1 - 0.00016 21.7 0.0 0.00091 19.2 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 ORY19717.1 - 0.00041 20.6 0.5 0.049 13.9 0.1 3.6 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 ORY19717.1 - 0.0018 18.4 0.8 0.047 13.9 0.0 3.3 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 ORY19717.1 - 0.002 18.5 0.0 0.0084 16.5 0.0 2.1 1 0 0 1 1 1 1 RNA helicase AAA_25 PF13481.6 ORY19717.1 - 0.0032 17.1 0.0 0.013 15.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 ORY19717.1 - 0.0042 17.6 0.5 0.044 14.3 0.0 2.9 3 0 0 3 3 2 1 ABC transporter AAA_14 PF13173.6 ORY19717.1 - 0.0054 16.8 0.0 0.038 14.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 ORY19717.1 - 0.0064 16.2 0.0 0.017 14.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 ORY19717.1 - 0.016 15.8 0.0 0.074 13.6 0.0 2.2 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 ORY19717.1 - 0.026 13.9 0.0 0.07 12.5 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 ORY19717.1 - 0.027 13.7 0.0 0.047 12.9 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain NACHT PF05729.12 ORY19717.1 - 0.033 14.1 0.1 0.11 12.5 0.0 2.0 2 0 0 2 2 1 0 NACHT domain RuvB_N PF05496.12 ORY19717.1 - 0.041 13.6 0.0 0.15 11.8 0.0 1.9 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 ORY19717.1 - 0.07 12.6 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_28 PF13521.6 ORY19717.1 - 0.091 13.0 0.2 0.31 11.3 0.0 2.0 2 0 0 2 2 1 0 AAA domain PhoH PF02562.16 ORY19717.1 - 0.1 12.1 0.1 0.38 10.2 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein AAA_3 PF07726.11 ORY19717.1 - 0.1 12.5 0.0 0.25 11.2 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.17 ORY19717.1 - 0.2 10.7 0.0 0.37 9.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_11 PF13086.6 ORY19717.1 - 0.34 10.7 0.0 0.34 10.7 0.0 3.4 2 1 0 2 2 1 0 AAA domain Biotin_lipoyl PF00364.22 ORY19719.1 - 1.9e-21 75.7 0.3 3.4e-21 74.8 0.3 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 ORY19719.1 - 1.5e-07 31.7 0.1 5e-07 30.0 0.1 1.9 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 ORY19719.1 - 4.6e-05 23.2 0.0 0.00025 20.8 0.0 2.1 2 0 0 2 2 2 1 Biotin-lipoyl like Mito_carr PF00153.27 ORY19720.1 - 2e-70 232.8 0.3 1.1e-24 86.2 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.32 ORY19720.1 - 8.6e-17 59.4 2.9 1.3e-06 27.6 0.0 5.2 5 0 0 5 5 5 2 EF hand EF-hand_6 PF13405.6 ORY19720.1 - 1.1e-14 53.0 4.2 6.1e-06 25.8 0.0 5.8 6 0 0 6 6 6 2 EF-hand domain EF-hand_7 PF13499.6 ORY19720.1 - 1.7e-14 54.0 3.5 1.9e-06 28.2 0.2 3.5 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 ORY19720.1 - 7e-10 38.0 5.9 9.4e-05 21.7 0.0 4.0 5 0 0 5 5 5 2 EF hand EF-hand_8 PF13833.6 ORY19720.1 - 3.1e-07 30.1 2.2 0.0059 16.4 0.3 4.9 4 1 0 4 4 4 2 EF-hand domain pair RNB PF00773.19 ORY19720.1 - 0.034 13.5 0.0 0.049 12.9 0.0 1.2 1 0 0 1 1 1 0 RNB domain Serine_protease PF18405.1 ORY19720.1 - 0.12 11.5 0.1 8.4 5.5 0.1 2.6 3 0 0 3 3 3 0 Gammaproteobacterial serine protease EF-hand_9 PF14658.6 ORY19720.1 - 0.18 12.2 0.0 3.6 8.0 0.0 2.8 3 0 0 3 3 3 0 EF-hand domain zf-C2H2 PF00096.26 ORY19721.1 - 2.6e-07 30.7 10.9 0.0061 16.9 2.0 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY19721.1 - 0.0044 17.4 12.0 0.89 10.1 0.2 3.7 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORY19721.1 - 0.015 16.1 10.2 0.13 13.2 1.7 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger zf-Di19 PF05605.12 ORY19721.1 - 0.14 12.5 6.9 0.59 10.5 1.0 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Cyclin_N PF00134.23 ORY19726.1 - 4.5e-38 129.9 0.9 8.4e-38 129.0 0.3 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 ORY19726.1 - 1.1e-10 41.6 3.4 1.2e-10 41.5 1.5 2.1 2 1 0 2 2 2 1 Cyclin, C-terminal domain Rad4 PF03835.15 ORY19728.1 - 1.4e-12 47.5 0.5 3e-12 46.4 0.5 1.5 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Transglut_core PF01841.19 ORY19728.1 - 1.6e-11 44.7 2.3 4.3e-11 43.3 2.3 1.8 1 0 0 1 1 1 1 Transglutaminase-like superfamily WD40 PF00400.32 ORY19728.1 - 5.9e-11 42.7 1.2 0.029 15.3 0.0 9.0 9 0 0 9 9 9 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY19728.1 - 7.5e-05 23.0 0.1 1.2 9.5 0.0 5.1 4 1 2 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 ORY19728.1 - 0.026 14.1 0.2 0.26 10.9 0.0 2.7 3 0 0 3 3 3 0 PQQ-like domain DUF5046 PF16465.5 ORY19728.1 - 0.033 13.6 0.0 0.06 12.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5046) SUR7 PF06687.12 ORY19730.1 - 6.6e-46 156.6 9.5 8.2e-46 156.3 9.5 1.1 1 0 0 1 1 1 1 SUR7/PalI family Abhydrolase_6 PF12697.7 ORY19731.1 - 3.1e-15 57.4 0.4 6.1e-15 56.4 0.4 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORY19731.1 - 1.4e-12 47.4 0.0 1.2e-11 44.4 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ORY19731.1 - 7.1e-09 35.7 0.5 1.3e-08 34.8 0.5 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.18 ORY19731.1 - 0.0085 15.7 0.0 0.15 11.6 0.0 2.2 2 0 0 2 2 2 1 Dienelactone hydrolase family Lipase_3 PF01764.25 ORY19731.1 - 0.049 13.5 0.0 0.095 12.6 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Thioesterase PF00975.20 ORY19731.1 - 0.065 13.3 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain BAAT_C PF08840.11 ORY19731.1 - 0.091 12.7 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_5 PF12695.7 ORY19731.1 - 0.17 11.6 0.0 5.5 6.7 0.0 2.7 3 0 0 3 3 3 0 Alpha/beta hydrolase family PAP2 PF01569.21 ORY19732.1 - 5.8e-30 103.8 0.2 1.2e-29 102.8 0.2 1.5 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 ORY19732.1 - 0.0012 18.5 0.8 0.0038 16.9 0.8 1.8 1 1 0 1 1 1 1 PAP2 superfamily UQ_con PF00179.26 ORY19734.1 - 1.3e-26 92.9 0.0 2.3e-26 92.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 ORY19734.1 - 0.21 11.5 0.0 0.4 10.5 0.0 1.4 1 0 0 1 1 1 0 UEV domain HCV_NS5a PF01506.19 ORY19734.1 - 4.2 7.4 6.1 29 4.7 0.1 2.5 2 0 0 2 2 2 0 Hepatitis C virus non-structural 5a protein membrane anchor PCI PF01399.27 ORY19735.1 - 1.1e-21 77.3 0.0 3.4e-21 75.7 0.0 1.8 1 0 0 1 1 1 1 PCI domain RPN5_C PF18098.1 ORY19735.1 - 3.6e-16 59.0 1.1 8.8e-16 57.7 1.1 1.7 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN5 C-terminal domain FSH1 PF03959.13 ORY19736.1 - 1.5e-65 220.9 0.0 1.9e-65 220.5 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 ORY19736.1 - 4.8e-05 24.1 0.2 7e-05 23.5 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 ORY19736.1 - 0.014 15.2 0.4 2.6 7.8 0.0 2.9 2 1 1 3 3 3 0 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 ORY19736.1 - 0.034 13.4 0.0 0.26 10.5 0.0 2.2 3 0 0 3 3 3 0 Serine aminopeptidase, S33 DLH PF01738.18 ORY19736.1 - 0.058 12.9 0.0 8 5.9 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family Esterase_phd PF10503.9 ORY19736.1 - 0.087 12.3 0.0 12 5.3 0.0 2.4 2 1 0 2 2 2 0 Esterase PHB depolymerase WD40 PF00400.32 ORY19737.1 - 1.1e-07 32.3 11.1 0.00014 22.6 0.3 3.7 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY19737.1 - 0.00042 20.6 0.0 3.7 7.9 0.0 3.6 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Gryzun-like PF12742.7 ORY19737.1 - 0.014 15.4 0.0 0.029 14.4 0.0 1.4 1 0 0 1 1 1 0 Gryzun, putative Golgi trafficking Nbas_N PF15492.6 ORY19737.1 - 0.07 12.4 0.0 0.19 11.0 0.0 1.7 2 0 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal Trp_halogenase PF04820.14 ORY19737.1 - 0.097 11.5 0.1 0.15 10.9 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase BicD PF09730.9 ORY19737.1 - 0.14 10.5 1.4 0.21 9.9 1.4 1.1 1 0 0 1 1 1 0 Microtubule-associated protein Bicaudal-D adh_short_C2 PF13561.6 ORY19738.1 - 9.5e-29 100.6 0.5 1.3e-28 100.2 0.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY19738.1 - 9.9e-24 83.9 0.3 1.5e-23 83.3 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORY19738.1 - 8.5e-07 29.0 1.0 1.2e-06 28.5 1.0 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 ORY19738.1 - 0.075 12.9 0.3 0.13 12.1 0.3 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Peptidase_C65 PF10275.9 ORY19742.1 - 6.8e-67 225.5 0.0 8.7e-67 225.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase C65 Otubain NFRKB_winged PF14465.6 ORY19742.1 - 0.069 13.3 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 NFRKB Winged Helix-like Calsequestrin PF01216.17 ORY19742.1 - 0.18 10.8 0.1 0.24 10.4 0.1 1.1 1 0 0 1 1 1 0 Calsequestrin PCI PF01399.27 ORY19743.1 - 4.8e-21 75.2 0.6 1.2e-20 74.0 0.6 1.7 1 0 0 1 1 1 1 PCI domain TPR_1 PF00515.28 ORY19743.1 - 0.017 14.9 1.0 0.16 11.9 0.2 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 ORY19743.1 - 0.13 12.5 0.1 0.13 12.5 0.1 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 ORY19743.1 - 0.14 12.2 1.9 16 5.8 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat Ras PF00071.22 ORY19744.1 - 1.1e-54 184.5 0.0 1.2e-54 184.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY19744.1 - 2.2e-21 76.3 0.0 3.5e-21 75.6 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY19744.1 - 2.9e-09 36.6 0.0 4.1e-09 36.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 ORY19744.1 - 0.0013 18.2 0.0 0.0023 17.4 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 ORY19744.1 - 0.0027 17.1 0.0 0.0033 16.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 ORY19744.1 - 0.006 15.8 0.0 0.04 13.1 0.0 1.5 1 1 1 2 2 2 1 G-protein alpha subunit MMR_HSR1 PF01926.23 ORY19744.1 - 0.056 13.5 0.0 0.09 12.9 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.27 ORY19744.1 - 0.093 13.2 0.0 0.12 12.9 0.0 1.3 1 0 0 1 1 1 0 ABC transporter AAA_16 PF13191.6 ORY19744.1 - 0.17 12.3 0.0 0.23 11.8 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain Ribosomal_S27e PF01667.17 ORY19745.1 - 1e-28 98.8 6.9 1.3e-28 98.5 6.9 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 zf-C2HC5 PF06221.13 ORY19745.1 - 1 9.4 7.2 4.4 7.4 4.5 2.3 2 1 0 2 2 2 0 Putative zinc finger motif, C2HC5-type DeoC PF01791.9 ORY19746.1 - 2e-14 53.8 1.5 3.5e-06 26.8 0.0 2.1 2 0 0 2 2 2 2 DeoC/LacD family aldolase His_biosynth PF00977.21 ORY19746.1 - 0.022 14.2 0.0 0.042 13.3 0.0 1.4 1 0 0 1 1 1 0 Histidine biosynthesis protein DHO_dh PF01180.21 ORY19746.1 - 0.083 12.1 0.0 0.2 10.8 0.0 1.6 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase S4 PF01479.25 ORY19747.1 - 1.1e-11 44.2 1.1 1.1e-11 44.2 1.1 2.2 2 0 0 2 2 2 1 S4 domain Ribosomal_S4 PF00163.19 ORY19747.1 - 1.2e-05 26.1 0.1 2.3e-05 25.2 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain Uds1 PF15456.6 ORY19747.1 - 0.048 13.8 0.2 4.9 7.3 0.0 2.2 2 0 0 2 2 2 0 Up-regulated During Septation Ribosomal_L21e PF01157.18 ORY19748.1 - 2.7e-44 149.1 3.2 2.7e-44 149.1 3.2 1.5 2 0 0 2 2 2 1 Ribosomal protein L21e Git3 PF11710.8 ORY19750.1 - 3e-25 89.2 16.6 4.7e-25 88.6 16.6 1.2 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 GPR_Gpa2_C PF11970.8 ORY19750.1 - 2.9e-06 27.3 0.1 2.9e-06 27.3 0.1 2.8 3 0 0 3 3 3 1 G protein-coupled glucose receptor regulating Gpa2 C-term Dicty_CAR PF05462.11 ORY19750.1 - 0.0056 15.9 14.6 0.0074 15.4 14.6 1.2 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor Git3 PF11710.8 ORY19751.1 - 6.3e-15 55.5 18.2 6.3e-15 55.5 18.2 1.7 2 1 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 GPR_Gpa2_C PF11970.8 ORY19751.1 - 8.9e-08 32.1 2.4 1.2e-07 31.7 0.1 2.4 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term SP24 PF16504.5 ORY19751.1 - 0.019 15.0 3.6 0.43 10.6 0.1 2.4 2 0 0 2 2 2 0 Putative virion membrane protein of plant and insect virus Jagunal PF07086.12 ORY19751.1 - 4.7 7.2 13.5 0.25 11.4 3.9 2.5 1 1 1 2 2 2 0 Jagunal, ER re-organisation during oogenesis DUF996 PF06195.13 ORY19751.1 - 5.8 7.2 13.4 1.4 9.2 3.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF996) Gram_pos_anchor PF00746.21 ORY19752.1 - 0.025 14.5 0.8 0.084 12.8 0.8 1.9 1 0 0 1 1 1 0 LPXTG cell wall anchor motif RAP1 PF07218.11 ORY19752.1 - 0.44 8.8 7.9 0.56 8.4 7.9 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF2062 PF09835.9 ORY19752.1 - 0.62 9.9 3.4 33 4.3 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2062) DUF3397 PF11877.8 ORY19753.1 - 0.036 14.3 1.4 0.036 14.3 1.4 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF3397) YdjM PF04307.14 ORY19753.1 - 0.038 13.3 4.9 0.43 9.9 0.1 2.6 1 1 1 2 2 2 0 LexA-binding, inner membrane-associated putative hydrolase Comm PF15957.5 ORY19753.1 - 0.43 10.9 0.0 0.43 10.9 0.0 2.1 2 1 0 2 2 2 0 Commissureless OST3_OST6 PF04756.13 ORY19753.1 - 0.46 9.8 0.0 0.46 9.8 0.0 2.5 3 0 0 3 3 3 0 OST3 / OST6 family, transporter family MFS_1 PF07690.16 ORY19755.1 - 4.3e-27 95.0 52.2 2.3e-21 76.1 33.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY19755.1 - 1e-14 54.3 25.1 3.5e-11 42.7 5.9 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter WD40 PF00400.32 ORY19756.1 - 2.8e-19 69.1 10.6 0.00056 20.7 0.1 6.7 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY19756.1 - 1e-15 57.8 0.1 6.1e-08 32.9 0.0 5.5 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ORY19756.1 - 4.8e-06 26.6 0.4 0.037 13.9 0.0 3.2 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 ORY19756.1 - 0.0031 16.5 0.0 10 4.9 0.0 3.3 2 1 1 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 ORY19756.1 - 0.62 10.1 6.3 15 5.7 0.4 4.0 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat RWD PF05773.22 ORY19757.1 - 0.0061 16.8 0.0 0.037 14.3 0.0 2.1 1 1 0 1 1 1 1 RWD domain Membralin PF09746.9 ORY19758.1 - 1.7 7.6 4.2 0.76 8.7 0.1 1.9 2 0 0 2 2 2 0 Tumour-associated protein AA_permease_2 PF13520.6 ORY19759.1 - 3.6e-58 197.4 51.5 4.6e-58 197.1 51.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ORY19759.1 - 5e-22 78.1 39.7 6.7e-22 77.7 39.7 1.0 1 0 0 1 1 1 1 Amino acid permease 60KD_IMP PF02096.20 ORY19759.1 - 0.11 12.4 6.9 0.1 12.5 3.5 2.3 2 1 0 2 2 2 0 60Kd inner membrane protein adh_short PF00106.25 ORY19760.1 - 1.1e-30 106.5 0.7 1.7e-21 76.6 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 ORY19760.1 - 7.2e-24 84.6 0.8 4.3e-19 69.0 0.0 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY19760.1 - 6e-06 26.3 0.1 1.2e-05 25.3 0.1 1.4 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 ORY19760.1 - 0.0023 17.4 0.0 0.019 14.3 0.0 2.0 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) Peripla_BP_6 PF13458.6 ORY19760.1 - 0.028 14.1 0.4 0.047 13.4 0.4 1.3 1 0 0 1 1 1 0 Periplasmic binding protein NAD_binding_10 PF13460.6 ORY19760.1 - 0.061 13.2 1.2 0.12 12.3 1.2 1.5 1 1 0 1 1 1 0 NAD(P)H-binding THF_DHG_CYH_C PF02882.19 ORY19760.1 - 0.081 12.2 0.1 0.16 11.3 0.1 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.21 ORY19760.1 - 0.12 11.8 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DSBA PF01323.20 ORY19761.1 - 1.7e-19 70.4 0.0 1.9e-19 70.2 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Myb_DNA-bind_4 PF13837.6 ORY19762.1 - 0.0013 19.1 1.7 0.0015 18.9 0.4 1.8 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain ATP_transf PF09830.9 ORY19763.1 - 1.2e-21 76.7 0.0 1.9e-21 75.9 0.0 1.4 1 0 0 1 1 1 1 ATP adenylyltransferase DUF4931 PF16285.5 ORY19763.1 - 1.8e-06 27.5 0.0 2.3e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4931) HIT PF01230.23 ORY19763.1 - 0.01 16.5 0.3 0.022 15.5 0.3 1.5 1 0 0 1 1 1 0 HIT domain GalP_UDP_transf PF01087.22 ORY19763.1 - 0.11 12.9 1.4 0.13 12.7 0.1 1.7 2 0 0 2 2 2 0 Galactose-1-phosphate uridyl transferase, N-terminal domain Atracotoxin PF05353.11 ORY19763.1 - 0.16 12.1 0.0 0.3 11.2 0.0 1.4 1 0 0 1 1 1 0 Delta Atracotoxin F-box-like PF12937.7 ORY19764.1 - 4.4e-12 45.7 1.2 6.3e-12 45.2 0.2 1.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 ORY19764.1 - 1.9e-05 24.4 2.2 4.7e-05 23.1 0.1 2.6 2 0 0 2 2 2 1 F-box domain LRR_4 PF12799.7 ORY19764.1 - 0.011 16.1 7.7 11 6.7 0.1 5.1 3 2 3 6 6 6 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 ORY19764.1 - 0.085 13.0 1.2 22 5.4 0.0 4.1 4 0 0 4 4 4 0 Leucine Rich repeat PTR2 PF00854.21 ORY19765.1 - 4.5e-84 282.6 3.6 6.8e-84 282.0 3.6 1.2 1 0 0 1 1 1 1 POT family MFS_1 PF07690.16 ORY19765.1 - 9.5e-12 44.5 16.5 9.5e-12 44.5 16.5 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF2207 PF09972.9 ORY19765.1 - 0.56 8.9 3.8 4.7 5.8 1.8 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) PFU PF09070.11 ORY19766.1 - 0.011 15.9 0.0 0.019 15.2 0.0 1.3 1 0 0 1 1 1 0 PFU (PLAA family ubiquitin binding) zf-His_Me_endon PF05551.11 ORY19768.1 - 5.5e-11 42.8 5.1 9.5e-11 42.0 5.1 1.4 1 0 0 1 1 1 1 Zinc-binding loop region of homing endonuclease Lactonase PF10282.9 ORY19769.1 - 1.5e-80 271.1 0.0 1.9e-80 270.8 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Hydrolase_6 PF13344.6 ORY19770.1 - 8.7e-24 83.6 0.0 5.6e-23 81.0 0.0 2.1 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ORY19770.1 - 2.8e-15 56.1 0.0 1.8e-14 53.5 0.0 2.3 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 ORY19770.1 - 0.00025 21.4 0.0 2.5 8.3 0.0 3.4 3 1 1 4 4 4 2 haloacid dehalogenase-like hydrolase Fungal_trans PF04082.18 ORY19771.1 - 1.5e-08 34.0 0.1 6.5e-08 31.9 0.1 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY19771.1 - 2.4e-06 27.5 10.8 3.7e-06 27.0 10.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_7 PF03441.14 ORY19772.1 - 5.7e-56 189.2 0.9 9.5e-56 188.5 0.9 1.4 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 ORY19772.1 - 1.7e-39 135.5 0.0 3.2e-39 134.6 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase T6PP_N PF18572.1 ORY19772.1 - 0.1 12.4 0.9 0.53 10.1 0.9 2.2 1 1 0 1 1 1 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain GFA PF04828.14 ORY19773.1 - 3.7e-16 59.3 1.9 6.1e-16 58.5 1.9 1.4 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme MFS_1 PF07690.16 ORY19774.1 - 2.1e-47 161.8 39.5 2.1e-47 161.8 39.5 1.6 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY19774.1 - 2e-12 46.7 11.2 2e-12 46.7 11.2 3.0 4 0 0 4 4 4 1 Sugar (and other) transporter YbjQ_1 PF01906.17 ORY19776.1 - 4.5e-30 104.4 1.4 5.4e-30 104.1 1.4 1.1 1 0 0 1 1 1 1 Putative heavy-metal-binding Cutinase PF01083.22 ORY19777.1 - 9.1e-44 149.5 4.1 1.2e-43 149.2 4.1 1.1 1 0 0 1 1 1 1 Cutinase Abhydrolase_1 PF00561.20 ORY19777.1 - 0.0034 17.0 0.1 0.011 15.4 0.1 1.6 1 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_9 PF10081.9 ORY19777.1 - 0.0046 16.1 0.0 0.0057 15.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta-hydrolase family Thioesterase PF00975.20 ORY19777.1 - 0.012 15.8 0.2 0.017 15.3 0.2 1.1 1 0 0 1 1 1 0 Thioesterase domain PE-PPE PF08237.11 ORY19777.1 - 0.015 14.9 0.3 0.022 14.3 0.3 1.2 1 0 0 1 1 1 0 PE-PPE domain Hydrolase_4 PF12146.8 ORY19777.1 - 0.03 13.6 0.2 0.042 13.1 0.2 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 LIP PF03583.14 ORY19777.1 - 0.045 13.1 0.4 0.078 12.3 0.4 1.4 1 0 0 1 1 1 0 Secretory lipase F_bP_aldolase PF01116.20 ORY19778.1 - 8.4e-77 258.4 0.0 1e-76 258.1 0.0 1.1 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Tautomerase PF01361.21 ORY19778.1 - 0.13 12.2 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 Tautomerase enzyme adh_short_C2 PF13561.6 ORY19779.1 - 1.4e-59 201.5 0.5 1.8e-59 201.1 0.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY19779.1 - 7.6e-47 159.3 0.3 9.6e-47 159.0 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORY19779.1 - 2.8e-07 30.6 0.0 4.1e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 KR domain SWIRM-assoc_3 PF16498.5 ORY19779.1 - 0.0032 17.7 1.8 0.0068 16.6 0.9 1.9 2 0 0 2 2 2 1 SWIRM-associated domain at the C-terminal ADH_zinc_N_2 PF13602.6 ORY19780.1 - 3.6e-17 63.6 0.0 5.5e-17 63.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 ORY19780.1 - 8.2e-13 48.5 0.0 1.4e-12 47.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ORY19780.1 - 0.003 17.4 0.0 0.0066 16.3 0.0 1.6 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain p450 PF00067.22 ORY19784.1 - 1.3e-53 182.4 0.0 1.9e-53 181.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 ORY19785.1 - 1.4e-14 53.8 37.3 3.3e-09 36.1 11.3 3.2 3 0 0 3 3 3 3 Major Facilitator Superfamily DUF3114 PF11311.8 ORY19786.1 - 0.15 11.5 0.2 0.19 11.2 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3114) PIN_4 PF13638.6 ORY19787.1 - 5.3e-05 23.5 0.0 0.00057 20.2 0.0 2.2 2 0 0 2 2 2 1 PIN domain FoP_duplication PF13865.6 ORY19787.1 - 9.3 6.9 10.7 25 5.5 10.7 1.7 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Translin PF01997.16 ORY19788.1 - 1.8e-69 233.9 0.2 2.1e-69 233.6 0.2 1.0 1 0 0 1 1 1 1 Translin family Sigma70_ner PF04546.13 ORY19788.1 - 0.062 13.2 2.3 0.092 12.6 0.8 1.9 2 0 0 2 2 2 0 Sigma-70, non-essential region Mannosyl_trans PF05007.13 ORY19789.1 - 3.5e-81 272.9 8.9 3.5e-81 272.9 8.9 1.6 2 0 0 2 2 2 1 Mannosyltransferase (PIG-M) PIG-U PF06728.13 ORY19789.1 - 3e-11 43.0 1.8 3e-11 43.0 1.8 2.1 2 0 0 2 2 2 1 GPI transamidase subunit PIG-U GT87 PF09594.10 ORY19789.1 - 1.6e-05 24.7 14.5 1.6e-05 24.7 14.5 2.7 2 1 0 2 2 2 1 Glycosyltransferase family 87 HPD PF05044.12 ORY19789.1 - 0.09 12.6 0.1 0.18 11.7 0.1 1.4 1 0 0 1 1 1 0 Homeo-prospero domain Glyco_trans_2_3 PF13632.6 ORY19790.1 - 2.7e-49 167.8 2.1 2.7e-49 167.8 2.1 2.5 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 ORY19790.1 - 0.014 15.2 0.0 0.057 13.2 0.0 1.9 2 0 0 2 2 2 0 Glycosyl transferase family 2 WSC PF01822.19 ORY19791.1 - 2.4e-71 236.0 79.6 3.4e-19 68.8 9.5 5.4 5 0 0 5 5 5 5 WSC domain Glyoxal_oxid_N PF07250.11 ORY19791.1 - 1.9e-27 96.0 0.0 2.7e-26 92.2 0.0 2.4 2 1 0 2 2 2 1 Glyoxal oxidase N-terminus DUF1929 PF09118.11 ORY19791.1 - 3.7e-22 78.4 0.1 1.7e-21 76.3 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1929) Glyco_hydro_16 PF00722.21 ORY19791.1 - 2.8e-16 59.5 0.0 7.8e-16 58.0 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 DUF3439 PF11921.8 ORY19791.1 - 0.24 11.4 2.5 0.33 10.9 0.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) VIT PF08487.10 ORY19793.1 - 1.8e-31 108.7 1.8 6.5e-31 106.8 0.0 2.7 3 0 0 3 3 3 1 Vault protein inter-alpha-trypsin domain VWA_3 PF13768.6 ORY19793.1 - 5.6e-29 101.1 0.0 9.8e-28 97.0 0.0 2.4 2 0 0 2 2 2 1 von Willebrand factor type A domain VIT_2 PF13757.6 ORY19793.1 - 1.5e-11 44.0 0.0 4.8e-11 42.4 0.0 1.9 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA PF00092.28 ORY19793.1 - 1.5e-11 44.9 0.0 3.2e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 ORY19793.1 - 1.6e-06 28.7 0.0 5.4e-06 27.0 0.0 2.0 1 0 0 1 1 1 1 von Willebrand factor type A domain Ribosomal_60s PF00428.19 ORY19793.1 - 2.7e-05 24.7 3.2 2.7e-05 24.7 3.2 3.9 5 0 0 5 5 5 1 60s Acidic ribosomal protein Macscav_rec PF03523.13 ORY19793.1 - 0.029 14.3 0.0 0.058 13.3 0.0 1.5 1 0 0 1 1 1 0 Macrophage scavenger receptor GST_N_3 PF13417.6 ORY19794.1 - 2.2e-12 47.2 3.0 3.5e-08 33.8 0.1 3.5 2 1 1 3 3 3 2 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 ORY19794.1 - 1e-07 32.1 0.4 5.9e-06 26.5 0.0 3.2 2 1 1 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 ORY19794.1 - 1.6e-06 28.0 0.3 0.0045 17.0 0.0 2.8 2 0 0 2 2 2 2 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 ORY19794.1 - 0.0036 17.6 0.0 0.36 11.2 0.0 2.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 ORY19794.1 - 0.012 16.4 0.0 0.036 14.8 0.0 1.8 1 1 0 1 1 1 0 Glutathione S-transferase N-terminal domain adh_short PF00106.25 ORY19795.1 - 4e-19 68.8 0.0 2e-18 66.6 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 ORY19795.1 - 2e-08 34.3 0.0 3.1e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 ORY19795.1 - 2.2e-07 30.7 0.0 3.6e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Shikimate_DH PF01488.20 ORY19795.1 - 0.034 14.2 0.0 0.086 12.9 0.0 1.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.21 ORY19795.1 - 0.11 11.9 0.0 0.19 11.1 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 ORY19795.1 - 0.18 10.9 0.0 0.25 10.4 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF3431 PF11913.8 ORY19796.1 - 3.5e-85 285.1 0.0 4.7e-85 284.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Glyco_hydro_18 PF00704.28 ORY19797.1 - 7e-88 295.3 7.3 8.1e-88 295.1 7.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Metallophos_2 PF12850.7 ORY19798.1 - 0.0065 16.7 0.0 2.8 8.1 0.0 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain zf-HC5HC2H_2 PF13832.6 ORY19799.1 - 4.1e-31 107.4 9.9 4.1e-31 107.4 9.9 2.4 2 0 0 2 2 2 1 PHD-zinc-finger like domain EPL1 PF10513.9 ORY19799.1 - 3.5e-28 99.0 0.0 9.8e-28 97.5 0.0 1.8 1 0 0 1 1 1 1 Enhancer of polycomb-like zf-HC5HC2H PF13771.6 ORY19799.1 - 8e-26 90.1 17.4 1.2e-25 89.6 8.4 2.6 2 0 0 2 2 2 2 PHD-like zinc-binding domain PHD_2 PF13831.6 ORY19799.1 - 1.8e-14 53.0 1.8 1.8e-14 53.0 1.8 2.3 2 0 0 2 2 2 1 PHD-finger PHD PF00628.29 ORY19799.1 - 1.4e-08 34.5 9.1 1.4e-08 34.5 9.1 2.6 2 0 0 2 2 2 1 PHD-finger RRM_1 PF00076.22 ORY19800.1 - 1.3e-19 69.7 0.0 1.9e-19 69.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 ORY19800.1 - 0.0022 17.6 0.0 0.003 17.2 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3431 PF11913.8 ORY19801.1 - 6.9e-89 297.3 2.4 9.2e-89 296.9 2.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) ExbD PF02472.16 ORY19801.1 - 0.09 13.0 0.2 0.55 10.4 0.1 2.2 2 0 0 2 2 2 0 Biopolymer transport protein ExbD/TolR MDH PF02315.16 ORY19801.1 - 0.83 9.8 3.9 0.83 9.8 0.6 2.4 2 0 0 2 2 2 0 Methanol dehydrogenase beta subunit Remorin_C PF03763.13 ORY19801.1 - 1.3 9.0 10.0 2 8.3 10.0 1.3 1 0 0 1 1 1 0 Remorin, C-terminal region ANAPC15 PF15243.6 ORY19803.1 - 2.6 8.5 7.7 4.2 7.8 0.1 3.2 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 15 DNA_binding_1 PF01035.20 ORY19804.1 - 3.1e-26 91.3 0.0 3.7e-26 91.1 0.0 1.1 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Agarase_CBM PF17992.1 ORY19804.1 - 0.065 12.8 0.0 1 8.9 0.0 2.0 2 0 0 2 2 2 0 Agarase CBM like domain TPR_17 PF13431.6 ORY19805.1 - 0.00077 19.7 5.9 0.16 12.4 0.3 4.9 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 ORY19805.1 - 1.6 9.1 12.0 9.7 6.6 0.3 4.5 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 ORY19805.1 - 3.7 8.6 13.4 0.8 10.7 0.1 5.7 6 2 0 6 6 6 0 Tetratricopeptide repeat Pkinase PF00069.25 ORY19806.1 - 1.4e-24 86.9 0.0 3e-24 85.8 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY19806.1 - 5.6e-13 48.8 0.0 8.6e-13 48.2 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 ORY19806.1 - 0.021 14.2 0.0 0.043 13.2 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1090 PF06476.12 ORY19806.1 - 0.021 14.9 0.6 0.032 14.3 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1090) FlxA PF14282.6 ORY19806.1 - 0.044 13.8 0.3 0.11 12.5 0.0 1.7 2 0 0 2 2 2 0 FlxA-like protein DUF1192 PF06698.11 ORY19806.1 - 0.078 13.0 0.2 6 7.0 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) CENP-F_leu_zip PF10473.9 ORY19806.1 - 0.088 12.8 1.3 0.18 11.8 1.3 1.5 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Shugoshin_N PF07558.11 ORY19806.1 - 0.43 10.5 4.4 2.7 7.9 0.2 3.2 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region Ribophorin_II PF05817.14 ORY19808.1 - 3.8e-32 111.7 0.0 4.3e-32 111.5 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II PhoLip_ATPase_C PF16212.5 ORY19808.1 - 0.021 14.6 0.1 0.03 14.1 0.1 1.1 1 0 0 1 1 1 0 Phospholipid-translocating P-type ATPase C-terminal DUF3336 PF11815.8 ORY19809.1 - 1.6e-35 121.9 0.1 2.8e-35 121.0 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 ORY19809.1 - 5.3e-21 75.7 0.0 8.9e-21 75.0 0.0 1.3 1 0 0 1 1 1 1 Patatin-like phospholipase Acyl-CoA_dh_1 PF00441.24 ORY19811.1 - 1e-42 145.9 0.4 1.5e-42 145.4 0.4 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 ORY19811.1 - 5.1e-22 77.9 0.1 9.2e-22 77.1 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.28 ORY19811.1 - 4.9e-20 71.4 0.3 1e-19 70.4 0.3 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.16 ORY19811.1 - 3.5e-18 66.3 0.0 8e-18 65.2 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 ORY19811.1 - 7.2e-09 36.0 0.0 1.2e-08 35.4 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain C6 PF01681.17 ORY19811.1 - 0.061 13.9 0.1 0.33 11.5 0.0 2.1 1 1 1 2 2 2 0 C6 domain Cupin_2 PF07883.11 ORY19812.1 - 3.2e-11 42.8 1.6 4.7e-11 42.2 1.0 1.5 2 0 0 2 2 2 1 Cupin domain Cupin_1 PF00190.22 ORY19812.1 - 4.3e-05 23.2 0.0 4.6e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.12 ORY19812.1 - 0.02 14.6 0.2 0.041 13.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF861) AraC_binding PF02311.19 ORY19812.1 - 0.044 13.7 0.1 0.055 13.4 0.1 1.2 1 0 0 1 1 1 0 AraC-like ligand binding domain Glyco_hydro_92 PF07971.12 ORY19813.1 - 2.1e-132 442.4 0.3 2.6e-132 442.1 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 ORY19813.1 - 8.2e-57 192.8 5.5 1.2e-56 192.3 5.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain M157 PF11624.8 ORY19813.1 - 0.12 11.8 0.0 1.2 8.4 0.0 2.0 2 0 0 2 2 2 0 MHC class I-like protein M157 Na_H_Exchanger PF00999.21 ORY19814.1 - 7e-58 196.2 43.5 1e-57 195.7 43.5 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Ribosomal_S5 PF00333.20 ORY19815.1 - 2.7e-27 94.6 1.0 7e-27 93.2 1.0 1.7 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 ORY19815.1 - 5.2e-23 80.3 0.0 8.6e-23 79.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain FoP_duplication PF13865.6 ORY19815.1 - 0.78 10.3 13.4 1.7 9.3 13.4 1.5 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 SKA2 PF16740.5 ORY19816.1 - 0.00078 19.2 6.9 3.9 7.3 0.2 4.3 5 0 0 5 5 5 3 Spindle and kinetochore-associated protein 2 FUSC PF04632.12 ORY19816.1 - 1.6 7.2 4.9 2.9 6.3 4.9 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family FapA PF03961.13 ORY19816.1 - 3 6.4 4.1 1.6 7.3 2.0 1.6 2 0 0 2 2 2 0 Flagellar Assembly Protein A Abhydrolase_6 PF12697.7 ORY19817.1 - 0.015 15.9 8.0 0.058 14.0 8.0 1.9 1 1 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 ORY19817.1 - 0.063 12.8 0.0 0.66 9.5 0.0 2.0 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Amidase PF01425.21 ORY19818.1 - 1.6e-100 337.2 0.0 2.2e-100 336.8 0.0 1.2 1 0 0 1 1 1 1 Amidase adh_short_C2 PF13561.6 ORY19819.1 - 9.1e-58 195.6 0.0 1.1e-57 195.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY19819.1 - 6.7e-49 166.0 0.1 9.1e-49 165.6 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORY19819.1 - 1.3e-14 54.5 0.0 1.9e-14 54.0 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ORY19819.1 - 0.0044 16.5 0.0 0.0062 16.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ORY19819.1 - 0.062 12.7 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase ZZ PF00569.17 ORY19820.1 - 5.6e-12 45.3 6.5 9.7e-12 44.5 6.5 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type EF-hand_1 PF00036.32 ORY19820.1 - 2.2e-10 39.3 3.3 0.0014 18.1 0.2 3.9 4 0 0 4 4 4 2 EF hand EF-hand_7 PF13499.6 ORY19820.1 - 3e-09 37.2 0.2 0.0013 19.1 0.0 4.1 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_6 PF13405.6 ORY19820.1 - 6.4e-09 35.0 4.0 0.00052 19.7 0.0 4.1 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.6 ORY19820.1 - 0.00093 19.0 2.3 5.1 7.0 0.0 4.1 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 ORY19820.1 - 0.081 12.5 4.2 0.22 11.1 0.1 3.1 4 0 0 4 4 4 0 EF hand WD40 PF00400.32 ORY19821.1 - 1.3e-18 67.0 21.1 6.3e-05 23.7 0.1 10.1 10 0 0 10 10 10 6 WD domain, G-beta repeat Polysacc_synt_4 PF04669.13 ORY19822.1 - 5.7e-23 81.5 1.0 2.6e-21 76.1 1.0 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis AChE_tetra PF08674.10 ORY19822.1 - 0.67 9.7 4.2 1.9 8.3 1.7 2.6 2 0 0 2 2 2 0 Acetylcholinesterase tetramerisation domain ABC_membrane PF00664.23 ORY19823.1 - 1e-90 304.1 30.2 5.4e-47 160.7 10.2 3.0 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 ORY19823.1 - 1e-59 201.0 0.0 2.2e-28 99.5 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 ORY19823.1 - 4.2e-13 49.2 0.8 3.2e-05 23.5 0.2 4.4 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 ORY19823.1 - 4.2e-10 40.0 1.2 0.0021 18.3 0.2 3.9 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.6 ORY19823.1 - 1.8e-08 34.9 1.2 0.00097 19.6 0.0 3.9 3 2 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.6 ORY19823.1 - 2.8e-08 33.4 0.4 0.002 17.8 0.0 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_ATPase PF09818.9 ORY19823.1 - 5.3e-06 25.5 0.6 0.002 17.0 0.1 3.2 3 0 0 3 3 3 1 Predicted ATPase of the ABC class AAA_25 PF13481.6 ORY19823.1 - 1.1e-05 25.1 0.1 0.46 10.0 0.0 3.9 4 0 0 4 4 4 2 AAA domain AAA_21 PF13304.6 ORY19823.1 - 2.1e-05 24.5 0.2 0.46 10.2 0.0 4.0 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 ORY19823.1 - 8.3e-05 22.4 1.0 0.93 9.2 0.3 3.6 2 2 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 ORY19823.1 - 0.00011 22.2 0.0 0.68 9.8 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 ORY19823.1 - 0.00033 21.2 0.0 0.03 14.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 ORY19823.1 - 0.00047 20.2 0.2 0.35 10.9 0.0 3.4 4 0 0 4 4 3 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 ORY19823.1 - 0.00065 20.2 0.0 1.2 9.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 ORY19823.1 - 0.00072 19.4 0.0 0.21 11.2 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 ORY19823.1 - 0.0015 18.7 0.1 0.87 9.7 0.0 3.0 2 0 0 2 2 2 1 AAA domain DUF3987 PF13148.6 ORY19823.1 - 0.0019 17.3 0.0 0.41 9.6 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3987) DUF87 PF01935.17 ORY19823.1 - 0.0052 16.9 2.0 0.34 11.0 0.1 2.7 2 0 0 2 2 2 1 Helicase HerA, central domain NB-ARC PF00931.22 ORY19823.1 - 0.012 14.8 0.0 4 6.6 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain NACHT PF05729.12 ORY19823.1 - 0.016 15.2 0.1 5.7 6.8 0.0 2.6 2 0 0 2 2 2 0 NACHT domain SbcCD_C PF13558.6 ORY19823.1 - 0.03 14.5 1.8 4 7.7 0.2 3.6 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit ATPase PF06745.13 ORY19823.1 - 0.033 13.5 1.2 11 5.3 0.0 3.1 3 0 0 3 3 3 0 KaiC AAA PF00004.29 ORY19823.1 - 0.042 14.3 1.1 9.4 6.7 0.3 3.9 2 2 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 ORY19823.1 - 0.043 14.2 0.0 9.1 6.7 0.0 2.6 2 0 0 2 2 2 0 RNA helicase IstB_IS21 PF01695.17 ORY19823.1 - 0.055 13.2 0.6 12 5.6 0.0 3.8 4 0 0 4 4 4 0 IstB-like ATP binding protein MMR_HSR1 PF01926.23 ORY19823.1 - 0.07 13.2 0.7 17 5.5 0.2 2.7 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_24 PF13479.6 ORY19823.1 - 0.072 12.8 0.0 4 7.1 0.0 2.6 3 0 0 3 3 3 0 AAA domain DUF2075 PF09848.9 ORY19823.1 - 0.1 11.8 0.0 2.8 7.1 0.0 2.5 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) PRK PF00485.18 ORY19823.1 - 0.11 12.2 0.1 20 4.8 0.0 2.6 2 1 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family ATP_bind_1 PF03029.17 ORY19823.1 - 0.19 11.5 0.2 16 5.2 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Popeye PF04831.13 ORY19823.1 - 0.4 10.9 2.9 0.43 10.8 0.2 2.4 2 0 0 2 2 2 0 Popeye protein conserved region APS_kinase PF01583.20 ORY19823.1 - 0.87 9.5 2.7 10 6.0 0.0 2.8 3 0 0 3 3 2 0 Adenylylsulphate kinase BRCT_2 PF16589.5 ORY19824.1 - 0.00029 21.2 0.0 0.00058 20.2 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 ORY19824.1 - 0.0088 16.0 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 ORY19824.1 - 0.014 15.8 0.0 0.031 14.6 0.0 1.6 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain Ndc1_Nup PF09531.10 ORY19825.1 - 6.9 5.2 6.3 8.2 5.0 6.3 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DAHP_synth_2 PF01474.16 ORY19827.1 - 1.3e-206 686.3 0.0 1.5e-206 686.1 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family Zn_clus PF00172.18 ORY19830.1 - 2.3e-07 30.8 6.6 4.7e-07 29.8 6.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Syncollin PF15138.6 ORY19830.1 - 0.047 13.9 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 Syncollin DHHC PF01529.20 ORY19836.1 - 1.8e-33 115.5 7.0 4.4e-33 114.2 7.0 1.6 1 0 0 1 1 1 1 DHHC palmitoyltransferase SET PF00856.28 ORY19837.1 - 6.8e-15 55.8 0.2 6.8e-15 55.8 0.2 4.0 3 2 0 3 3 3 1 SET domain AWS PF17907.1 ORY19837.1 - 1.9e-07 31.0 3.4 1.9e-07 31.0 3.4 2.1 2 0 0 2 2 2 1 AWS domain PMT PF02366.18 ORY19838.1 - 1.9e-83 279.8 14.5 1.9e-83 279.8 14.5 1.6 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 ORY19838.1 - 3.7e-66 222.5 13.3 3.7e-66 222.5 13.3 1.9 2 0 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 ORY19838.1 - 1.8e-46 158.3 0.0 3.2e-46 157.5 0.0 1.4 1 0 0 1 1 1 1 MIR domain DUF2530 PF10745.9 ORY19838.1 - 0.035 14.3 2.7 0.24 11.7 0.2 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) PRP21_like_P PF12230.8 ORY19839.1 - 4.1e-54 183.7 1.2 9.4e-54 182.5 1.2 1.6 1 1 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.20 ORY19839.1 - 9.9e-28 95.9 4.2 5.4e-14 51.9 0.6 2.6 2 0 0 2 2 2 2 Surp module zf-C2HC_2 PF13913.6 ORY19839.1 - 0.039 13.9 0.1 0.062 13.2 0.1 1.3 1 0 0 1 1 1 0 zinc-finger of a C2HC-type Complex1_LYR PF05347.15 ORY19840.1 - 6.7e-19 67.7 7.1 1e-18 67.1 7.1 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 ORY19840.1 - 8.5e-07 29.6 2.7 9.6e-07 29.5 2.7 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.6 ORY19840.1 - 0.004 17.7 0.6 0.0051 17.4 0.6 1.3 1 0 0 1 1 1 1 Complex1_LYR-like SVIP PF15811.5 ORY19840.1 - 0.0083 16.5 1.4 0.014 15.8 1.4 1.3 1 0 0 1 1 1 1 Small VCP/p97-interacting protein Glutaredoxin2_C PF04399.13 ORY19840.1 - 0.078 12.8 0.2 0.093 12.6 0.2 1.1 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain VitD-bind_III PF09164.10 ORY19840.1 - 0.2 11.7 0.4 0.3 11.1 0.4 1.2 1 0 0 1 1 1 0 Vitamin D binding protein, domain III Peptidase_M20 PF01546.28 ORY19842.1 - 2.8e-19 69.6 0.0 4.4e-19 69.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 ORY19842.1 - 2.1e-15 56.6 0.2 4.5e-15 55.5 0.2 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain F-box-like PF12937.7 ORY19843.1 - 0.00028 20.7 0.0 0.00065 19.5 0.0 1.6 1 0 0 1 1 1 1 F-box-like MARVEL PF01284.23 ORY19844.1 - 2.5e-06 27.6 11.7 4.9e-06 26.6 11.7 1.4 1 1 0 1 1 1 1 Membrane-associating domain DUF4293 PF14126.6 ORY19844.1 - 0.0016 18.7 0.9 0.0047 17.2 0.2 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4293) 7TMR-DISM_7TM PF07695.11 ORY19844.1 - 0.017 15.0 4.4 0.017 15.0 4.4 2.0 2 0 0 2 2 2 0 7TM diverse intracellular signalling SUR7 PF06687.12 ORY19844.1 - 0.12 12.0 5.7 0.41 10.2 0.0 2.1 2 0 0 2 2 2 0 SUR7/PalI family DUF2339 PF10101.9 ORY19844.1 - 0.14 10.7 7.3 0.18 10.4 7.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2339) DUF2244 PF10003.9 ORY19844.1 - 9.7 5.9 11.2 1.8 8.3 0.0 2.5 3 0 0 3 3 3 0 Integral membrane protein (DUF2244) DUF496 PF04363.12 ORY19845.1 - 0.77 9.8 3.9 2.4 8.3 0.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF496) Ribosomal_S8 PF00410.19 ORY19846.1 - 1.3e-12 47.8 0.0 6.4e-11 42.3 0.0 2.7 1 1 0 1 1 1 1 Ribosomal protein S8 MGC-24 PF05283.11 ORY19849.1 - 0.00041 20.8 1.7 0.00062 20.2 1.7 1.3 1 0 0 1 1 1 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin EphA2_TM PF14575.6 ORY19849.1 - 0.0078 17.1 0.0 0.051 14.4 0.0 2.0 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain Amnionless PF14828.6 ORY19849.1 - 0.0095 14.8 0.0 0.012 14.5 0.0 1.1 1 0 0 1 1 1 1 Amnionless VSP PF03302.13 ORY19849.1 - 0.012 14.5 1.3 0.017 14.0 1.3 1.3 1 0 0 1 1 1 0 Giardia variant-specific surface protein TMEM154 PF15102.6 ORY19849.1 - 0.042 13.7 0.0 0.066 13.1 0.0 1.2 1 0 0 1 1 1 0 TMEM154 protein family TraL PF07178.11 ORY19849.1 - 0.049 14.1 0.2 0.12 12.9 0.2 1.6 2 0 0 2 2 2 0 TraL protein SKG6 PF08693.10 ORY19849.1 - 0.056 12.9 0.4 0.1 12.0 0.4 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF2207 PF09972.9 ORY19849.1 - 0.1 11.3 0.0 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) RicinB_lectin_2 PF14200.6 ORY19849.1 - 0.17 12.6 3.7 0.21 12.3 0.7 2.6 1 1 2 3 3 3 0 Ricin-type beta-trefoil lectin domain-like VPDSG-CTERM PF18205.1 ORY19849.1 - 1.6 8.6 5.2 1.7 8.5 3.5 2.1 1 1 0 1 1 1 0 VPDSG-CTERM motif SSP160 PF06933.11 ORY19849.1 - 2.1 6.4 13.6 2.7 6.1 13.6 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 NMT_C PF02799.15 ORY19850.1 - 4.3e-86 287.8 0.1 6.1e-86 287.3 0.1 1.2 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.19 ORY19850.1 - 1.2e-74 249.5 0.1 5.5e-72 240.8 0.0 2.2 2 0 0 2 2 2 2 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_9 PF13527.7 ORY19850.1 - 0.00012 22.1 0.0 0.00085 19.4 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORY19850.1 - 0.011 16.0 0.0 0.024 14.9 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family NTP_transf_9 PF04248.12 ORY19850.1 - 0.095 12.6 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF427) Ribosomal_L36 PF00444.18 ORY19851.1 - 4.8e-20 71.5 11.9 7e-20 70.9 11.9 1.3 1 0 0 1 1 1 1 Ribosomal protein L36 TLD PF07534.16 ORY19852.1 - 2.6e-26 92.5 0.0 1.5e-25 90.0 0.0 2.0 1 1 0 1 1 1 1 TLD DUF1773 PF08593.10 ORY19852.1 - 2.1e-15 57.5 0.0 4.9e-15 56.3 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function Glyco_hydro_61 PF03443.14 ORY19854.1 - 0.018 15.0 0.9 0.083 12.8 0.0 2.6 2 1 0 2 2 2 0 Glycosyl hydrolase family 61 Hydrolase_4 PF12146.8 ORY19857.1 - 2.9e-07 30.0 0.1 2.3e-06 27.0 0.1 2.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ORY19857.1 - 1.9e-06 28.7 0.5 3.1e-06 28.0 0.5 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ORY19857.1 - 0.0048 16.6 0.1 0.0077 15.9 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold GTP_EFTU PF00009.27 ORY19858.1 - 4.3e-59 199.3 0.1 7.1e-59 198.6 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 ORY19858.1 - 2.6e-34 117.6 0.1 5e-34 116.7 0.1 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.6 ORY19858.1 - 5.5e-34 116.1 0.0 1.2e-33 115.0 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 ORY19858.1 - 1.1e-23 83.0 0.0 2.7e-22 78.6 0.0 2.5 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 ORY19858.1 - 1.8e-13 50.7 0.0 3.8e-13 49.6 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 ORY19858.1 - 1.1e-07 31.7 0.0 2.3e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain DUF442 PF04273.13 ORY19858.1 - 0.012 15.7 0.0 0.13 12.3 0.0 2.5 2 0 0 2 2 2 0 Putative phosphatase (DUF442) RSN1_7TM PF02714.15 ORY19860.1 - 7.9e-83 277.9 20.2 7.9e-83 277.9 20.2 1.7 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 ORY19860.1 - 4.7e-42 143.4 2.1 1.5e-41 141.8 2.1 1.9 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 ORY19860.1 - 1.1e-27 97.3 0.2 1.7e-27 96.8 0.2 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 ORY19860.1 - 8e-24 83.6 0.1 2e-23 82.4 0.1 1.7 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter Not3 PF04065.15 ORY19860.1 - 0.026 14.0 1.1 0.053 12.9 0.1 1.8 2 0 0 2 2 2 0 Not1 N-terminal domain, CCR4-Not complex component SNARE PF05739.19 ORY19862.1 - 3.9e-11 42.8 1.7 4.4e-11 42.6 0.1 2.0 2 0 0 2 2 2 1 SNARE domain Syntaxin-5_N PF11416.8 ORY19862.1 - 8.3e-09 34.4 0.7 8.3e-09 34.4 0.7 2.2 2 0 0 2 2 2 1 Syntaxin-5 N-terminal, Sly1p-binding domain Syntaxin-18_N PF10496.9 ORY19862.1 - 0.00064 19.9 2.3 0.0056 16.9 0.3 2.4 2 0 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus Syntaxin PF00804.25 ORY19862.1 - 0.0047 16.6 0.3 0.0047 16.6 0.3 3.2 2 1 1 3 3 3 1 Syntaxin KxDL PF10241.9 ORY19862.1 - 0.0084 16.4 5.6 0.28 11.5 0.2 3.4 2 1 1 3 3 3 1 Uncharacterized conserved protein SlyX PF04102.12 ORY19862.1 - 0.0098 16.5 0.7 0.0098 16.5 0.7 3.1 3 0 0 3 3 3 1 SlyX DUF16 PF01519.16 ORY19862.1 - 0.037 14.5 4.0 0.042 14.3 0.9 2.4 2 0 0 2 2 2 0 Protein of unknown function DUF16 DUF948 PF06103.11 ORY19862.1 - 0.057 13.7 0.5 1.5 9.2 0.0 3.1 4 1 0 4 4 3 0 Bacterial protein of unknown function (DUF948) SOAR PF16533.5 ORY19862.1 - 0.14 12.1 0.3 0.14 12.1 0.3 2.3 2 0 0 2 2 2 0 STIM1 Orai1-activating region BLOC1_2 PF10046.9 ORY19862.1 - 0.35 11.2 2.7 0.85 10.0 0.2 2.8 3 1 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Snapin_Pallidin PF14712.6 ORY19862.1 - 1.1 9.7 5.4 1.1 9.7 0.2 3.0 3 0 0 3 3 3 0 Snapin/Pallidin DUF1664 PF07889.12 ORY19862.1 - 1.3 9.1 4.3 1.7 8.7 0.2 2.8 3 2 1 4 4 4 0 Protein of unknown function (DUF1664) NPV_P10 PF05531.12 ORY19862.1 - 1.9 9.0 5.6 30 5.1 0.0 3.5 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Fib_alpha PF08702.10 ORY19862.1 - 6.6 6.9 9.2 12 6.1 0.3 3.0 3 1 0 3 3 3 0 Fibrinogen alpha/beta chain family Septin PF00735.18 ORY19864.1 - 9.7e-32 110.4 0.0 2.5e-10 40.1 0.0 3.2 3 0 0 3 3 3 3 Septin MMR_HSR1 PF01926.23 ORY19864.1 - 8.5e-05 22.6 0.7 0.0032 17.5 0.0 2.6 3 0 0 3 3 3 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 ORY19864.1 - 0.0079 16.3 0.7 0.084 12.9 0.0 2.5 2 0 0 2 2 2 1 Dynamin family AAA_29 PF13555.6 ORY19864.1 - 0.0086 15.8 0.0 0.02 14.6 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 ORY19864.1 - 0.028 13.8 0.0 0.052 12.9 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family G-alpha PF00503.20 ORY19864.1 - 0.044 12.9 0.0 0.091 11.9 0.0 1.5 1 0 0 1 1 1 0 G-protein alpha subunit AAA_15 PF13175.6 ORY19864.1 - 0.082 12.6 0.0 0.17 11.5 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain GTP_EFTU PF00009.27 ORY19864.1 - 0.094 12.2 0.0 15 5.0 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain RNA_helicase PF00910.22 ORY19864.1 - 0.13 12.7 0.0 2.8 8.4 0.0 2.4 2 0 0 2 2 2 0 RNA helicase IIGP PF05049.13 ORY19864.1 - 0.15 11.1 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Roc PF08477.13 ORY19864.1 - 0.2 11.9 0.0 1.5 9.1 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Aft1_HRR PF11787.8 ORY19864.1 - 2.4 9.4 5.2 1.7 9.9 0.1 3.0 3 0 0 3 3 3 0 Aft1 HRR domain zf-FPG_IleRS PF06827.14 ORY19867.1 - 0.0065 16.3 6.9 0.026 14.4 6.9 2.0 1 1 0 1 1 1 1 Zinc finger found in FPG and IleRS zinc_ribbon_10 PF10058.9 ORY19867.1 - 0.03 14.0 0.5 0.048 13.4 0.5 1.4 1 0 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein Secretin_N_2 PF07655.13 ORY19867.1 - 0.05 14.2 9.3 0.055 14.0 9.3 1.1 1 0 0 1 1 1 0 Secretin N-terminal domain DUF508 PF04370.12 ORY19867.1 - 0.097 12.4 5.0 0.1 12.3 5.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF508) SR-25 PF10500.9 ORY19867.1 - 0.87 9.2 19.1 0.91 9.1 19.1 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Macoilin PF09726.9 ORY19867.1 - 6.9 5.1 6.3 6.8 5.1 6.3 1.0 1 0 0 1 1 1 0 Macoilin family SSP160 PF06933.11 ORY19867.1 - 7.7 4.6 15.0 8 4.5 15.0 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 CCDC106 PF15794.5 ORY19867.1 - 9.2 5.9 5.9 9.6 5.8 5.9 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 RAP1 PF07218.11 ORY19867.1 - 9.6 4.3 10.2 8.9 4.4 10.2 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) HeLo PF14479.6 ORY19868.1 - 8.5e-39 133.5 0.1 2.3e-38 132.1 0.1 1.8 1 0 0 1 1 1 1 Prion-inhibition and propagation Ank_2 PF12796.7 ORY19868.1 - 1.7e-36 124.6 0.1 3e-13 50.1 0.0 5.1 3 2 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY19868.1 - 9.6e-28 96.2 0.4 1.4e-09 38.3 0.1 6.3 3 2 3 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY19868.1 - 7e-27 90.5 0.2 0.0001 22.4 0.0 9.7 10 0 0 10 10 10 6 Ankyrin repeat Ank_5 PF13857.6 ORY19868.1 - 2e-26 91.7 0.4 2.7e-10 40.3 0.0 5.4 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 ORY19868.1 - 4.5e-25 86.9 3.1 2.5e-05 24.5 0.0 8.3 8 0 0 8 8 8 4 Ankyrin repeat AAA_16 PF13191.6 ORY19868.1 - 6.8e-06 26.6 0.0 0.00012 22.5 0.0 3.0 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 ORY19868.1 - 1.9e-05 24.6 0.4 0.00022 21.2 0.4 2.5 1 1 0 1 1 1 1 NACHT domain NB-ARC PF00931.22 ORY19868.1 - 0.004 16.4 0.0 0.017 14.3 0.0 2.0 1 1 0 1 1 1 1 NB-ARC domain AAA PF00004.29 ORY19868.1 - 0.054 13.9 0.4 0.46 10.9 0.1 2.8 2 1 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 ORY19868.1 - 0.13 11.9 0.0 0.28 10.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 ORY19868.1 - 0.17 11.6 0.0 0.35 10.6 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain DUF2951 PF11166.8 ORY19868.1 - 0.33 11.2 7.5 0.26 11.5 2.3 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF2951) Glucosamine_iso PF01182.20 ORY19869.1 - 1.3e-68 231.3 0.0 1.4e-68 231.1 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Enkurin PF13864.6 ORY19870.1 - 0.083 13.3 0.1 5.1 7.6 0.1 2.6 2 0 0 2 2 2 0 Calmodulin-binding PI3K_1B_p101 PF10486.9 ORY19870.1 - 0.18 9.6 3.6 0.24 9.1 3.6 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Rod_cone_degen PF15201.6 ORY19870.1 - 0.23 11.6 0.9 0.41 10.8 0.2 1.8 2 0 0 2 2 2 0 Progressive rod-cone degeneration Endomucin PF07010.12 ORY19870.1 - 1.1 9.2 10.6 1.6 8.6 10.6 1.3 1 0 0 1 1 1 0 Endomucin Tropomyosin_1 PF12718.7 ORY19871.1 - 0.0028 17.8 8.8 0.0028 17.8 8.8 3.0 3 1 1 4 4 3 1 Tropomyosin like MAD PF05557.13 ORY19871.1 - 0.0035 15.8 19.2 0.042 12.2 0.2 2.3 1 1 1 2 2 2 2 Mitotic checkpoint protein Imm7 PF15585.6 ORY19871.1 - 0.031 14.6 0.5 0.087 13.1 0.5 1.7 1 0 0 1 1 1 0 Immunity protein 7 FlaC_arch PF05377.11 ORY19871.1 - 0.077 13.4 6.4 0.29 11.6 3.3 2.8 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Spectrin PF00435.21 ORY19871.1 - 0.1 13.1 16.9 2.5 8.7 5.1 3.5 2 1 1 3 3 3 0 Spectrin repeat HALZ PF02183.18 ORY19871.1 - 0.1 12.8 7.1 0.14 12.4 0.7 3.1 2 1 1 3 3 2 0 Homeobox associated leucine zipper HOOK PF05622.12 ORY19871.1 - 0.32 9.1 18.5 0.68 8.0 16.7 2.0 1 1 1 2 2 2 0 HOOK protein ATG16 PF08614.11 ORY19871.1 - 0.34 11.1 22.8 0.61 10.3 14.0 2.8 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) CENP-F_leu_zip PF10473.9 ORY19871.1 - 0.4 10.7 22.9 4.8 7.2 0.1 4.0 3 1 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6_N PF17675.1 ORY19871.1 - 0.41 11.2 21.8 0.81 10.2 14.9 3.3 3 1 0 3 3 3 0 Apg6 coiled-coil region Sec34 PF04136.15 ORY19871.1 - 0.8 9.6 7.8 2.3 8.1 4.8 2.6 2 0 0 2 2 2 0 Sec34-like family TMF_TATA_bd PF12325.8 ORY19871.1 - 1.2 9.4 23.3 2.4 8.4 0.4 4.0 3 1 1 4 4 4 0 TATA element modulatory factor 1 TATA binding Fez1 PF06818.15 ORY19871.1 - 1.5 9.3 20.6 8.5 6.8 19.9 2.2 1 1 1 2 2 2 0 Fez1 UPF0242 PF06785.11 ORY19871.1 - 2 8.5 17.0 17 5.5 14.6 2.5 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Cep57_CLD_2 PF14197.6 ORY19871.1 - 2 8.6 20.1 0.65 10.1 3.5 3.9 3 1 1 4 4 3 0 Centrosome localisation domain of PPC89 Spc7 PF08317.11 ORY19871.1 - 2.6 6.8 19.5 1 8.1 15.3 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein Cep57_MT_bd PF06657.13 ORY19871.1 - 2.7 8.5 11.8 11 6.5 1.6 3.9 2 1 1 3 3 3 0 Centrosome microtubule-binding domain of Cep57 TPR_MLP1_2 PF07926.12 ORY19871.1 - 3.5 7.7 26.3 5.2 7.2 12.4 3.4 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein AAA_13 PF13166.6 ORY19871.1 - 5 5.6 11.1 2.9 6.4 5.5 2.1 1 1 1 2 2 2 0 AAA domain ADIP PF11559.8 ORY19871.1 - 5.6 7.0 24.4 1.3 9.1 11.8 3.2 3 1 1 4 4 4 0 Afadin- and alpha -actinin-Binding HalX PF08663.10 ORY19871.1 - 5.9 7.3 13.9 0.34 11.2 5.9 2.7 3 0 0 3 3 2 0 HalX domain TSC22 PF01166.18 ORY19871.1 - 6 7.3 6.6 4.7 7.6 0.1 3.0 2 1 1 3 3 3 0 TSC-22/dip/bun family TMF_DNA_bd PF12329.8 ORY19871.1 - 7.5 6.6 10.5 12 6.0 8.0 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding ERM PF00769.19 ORY19871.1 - 8 6.2 23.5 21 4.9 22.9 1.8 1 1 0 1 1 1 0 Ezrin/radixin/moesin family DUF1664 PF07889.12 ORY19871.1 - 9.7 6.3 9.5 6.1 6.9 4.2 2.6 3 0 0 3 3 2 0 Protein of unknown function (DUF1664) SMC_N PF02463.19 ORY19873.1 - 3.8e-62 209.6 0.0 9.3e-60 201.8 0.0 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 ORY19873.1 - 8.2e-28 97.1 0.0 2.9e-27 95.3 0.0 2.1 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_15 PF13175.6 ORY19873.1 - 6.4e-12 45.8 0.9 6.4e-12 45.8 0.9 4.5 2 2 1 4 4 2 1 AAA ATPase domain AAA_21 PF13304.6 ORY19873.1 - 1.1e-10 41.9 9.6 2e-05 24.6 0.1 4.4 4 2 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 ORY19873.1 - 7e-08 33.2 26.4 7e-08 33.2 26.4 6.6 3 2 1 4 4 2 1 AAA domain AAA_29 PF13555.6 ORY19873.1 - 1.5e-07 31.0 0.0 3.7e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_13 PF13166.6 ORY19873.1 - 0.00042 19.1 18.3 0.00042 19.1 18.3 5.3 2 2 3 5 5 5 2 AAA domain HMMR_N PF15905.5 ORY19873.1 - 0.0028 17.2 16.2 0.0028 17.2 16.2 5.9 4 1 2 6 6 5 1 Hyaluronan mediated motility receptor N-terminal DUF1664 PF07889.12 ORY19873.1 - 0.0087 16.1 3.4 0.0087 16.1 3.4 8.5 5 3 3 9 9 9 2 Protein of unknown function (DUF1664) ADIP PF11559.8 ORY19873.1 - 0.011 15.9 8.9 0.011 15.9 8.9 7.7 4 2 4 8 8 7 0 Afadin- and alpha -actinin-Binding Osmo_CC PF08946.10 ORY19873.1 - 0.013 15.7 0.6 0.013 15.7 0.6 5.4 5 0 0 5 5 4 0 Osmosensory transporter coiled coil SbcCD_C PF13558.6 ORY19873.1 - 0.018 15.3 0.0 0.13 12.5 0.0 2.6 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit DUF2838 PF10998.8 ORY19874.1 - 5.7e-45 152.1 8.4 5.7e-45 152.1 8.4 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2838) TssR PF17643.1 ORY19874.1 - 0.16 9.9 0.2 0.21 9.5 0.2 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssR MtrB PF05440.12 ORY19874.1 - 0.17 12.3 0.0 1 9.8 0.0 2.0 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase subunit B Val_tRNA-synt_C PF10458.9 ORY19874.1 - 0.25 11.7 1.9 25 5.2 1.7 2.4 2 0 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm Exonuc_VII_L PF02601.15 ORY19874.1 - 0.25 10.8 1.3 0.37 10.3 1.3 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Serglycin PF04360.12 ORY19875.1 - 5.2 7.0 6.9 22 5.0 0.0 2.4 2 0 0 2 2 2 0 Serglycin SSrecog PF03531.14 ORY19876.1 - 4.2e-30 103.5 2.1 1.7e-29 101.5 0.0 3.0 4 0 0 4 4 4 1 Structure-specific recognition protein (SSRP1) POB3_N PF17292.2 ORY19876.1 - 7.2e-27 93.7 0.4 5.4e-26 90.8 0.2 2.4 2 0 0 2 2 2 1 POB3-like N-terminal PH domain Rtt106 PF08512.12 ORY19876.1 - 1e-26 93.1 0.0 8e-26 90.3 0.0 2.3 2 0 0 2 2 2 1 Histone chaperone Rttp106-like DUF4974 PF16344.5 ORY19876.1 - 0.027 14.4 0.5 1.5 8.9 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4974) YL1 PF05764.13 ORY19876.1 - 7.5 6.6 18.4 0.8 9.8 13.7 1.8 2 0 0 2 2 2 0 YL1 nuclear protein Fungal_trans_2 PF11951.8 ORY19877.1 - 6.7e-10 38.3 0.1 9.2e-07 28.0 0.0 2.5 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY19877.1 - 1.7e-05 24.8 15.1 1.7e-05 24.8 15.1 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Actino_peptide PF14408.6 ORY19878.1 - 0.23 11.6 3.6 0.4 10.8 0.0 2.4 2 0 0 2 2 2 0 Ribosomally synthesised peptide in actinomycetes Activin_recp PF01064.23 ORY19880.1 - 0.66 11.1 9.0 0.3 12.2 1.7 2.2 2 0 0 2 2 2 0 Activin types I and II receptor domain GST_C_3 PF14497.6 ORY19881.1 - 0.084 13.1 0.0 0.13 12.5 0.0 1.4 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Fungal_trans PF04082.18 ORY19882.1 - 6.6e-18 64.7 1.2 1.2e-17 63.8 1.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DFP PF04127.15 ORY19883.1 - 7.5e-15 55.2 0.0 6.9e-06 26.0 0.0 3.6 2 1 1 3 3 3 2 DNA / pantothenate metabolism flavoprotein MFS_1 PF07690.16 ORY19884.1 - 9.5e-30 103.7 28.5 9.5e-30 103.7 28.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Nrap_D5 PF17406.2 ORY19885.1 - 0.077 12.8 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Nrap protein PAP/OAS1-like domain 5 zf_UBZ PF18439.1 ORY19885.1 - 2 8.1 5.1 4.9 6.8 0.4 2.4 1 1 1 2 2 2 0 Ubiquitin-Binding Zinc Finger Glyoxal_oxid_N PF07250.11 ORY19886.1 - 1.7e-40 138.7 0.0 1.8e-39 135.3 0.0 2.6 2 1 0 2 2 2 1 Glyoxal oxidase N-terminus Chitin_bind_1 PF00187.19 ORY19886.1 - 1.2e-27 96.1 114.4 1.4e-07 31.8 23.0 4.8 5 0 0 5 5 5 4 Chitin recognition protein DUF1929 PF09118.11 ORY19886.1 - 4.7e-25 87.7 0.4 1e-24 86.6 0.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Phage_B PF02304.15 ORY19886.1 - 1.9 8.9 6.4 21 5.5 0.3 2.6 2 0 0 2 2 2 0 Scaffold protein B K_channel_TID PF07941.11 ORY19887.1 - 0.025 15.0 5.2 0.045 14.2 5.2 1.3 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain SelK_SelG PF10961.8 ORY19887.1 - 2 9.1 7.6 4.7 7.9 4.1 2.2 1 1 1 2 2 2 0 Selenoprotein SelK_SelG RPN7 PF10602.9 ORY19888.1 - 9.5e-42 142.6 0.3 1.6e-41 141.9 0.3 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 ORY19888.1 - 3.4e-12 46.8 0.0 1.4e-11 44.8 0.0 1.9 2 0 0 2 2 2 1 PCI domain Cnn_1N PF07989.11 ORY19888.1 - 0.072 13.2 0.1 0.17 12.1 0.1 1.6 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 TPR_2 PF07719.17 ORY19888.1 - 0.1 12.8 0.0 3.4 8.0 0.4 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat DMPK_coil PF08826.10 ORY19888.1 - 0.73 10.0 3.3 2.7 8.2 0.5 2.5 2 0 0 2 2 2 0 DMPK coiled coil domain like AAA_30 PF13604.6 ORY19889.1 - 1.3e-11 44.5 0.0 1.7e-11 44.2 0.0 1.1 1 0 0 1 1 1 1 AAA domain PIF1 PF05970.14 ORY19889.1 - 5.9e-09 35.6 0.0 7.4e-09 35.2 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase AAA_19 PF13245.6 ORY19889.1 - 1.5e-06 28.7 0.0 2e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain MeaB PF03308.16 ORY19889.1 - 0.00018 20.6 0.0 0.00026 20.1 0.0 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_29 PF13555.6 ORY19889.1 - 0.00082 19.1 0.1 0.0015 18.2 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain PRK PF00485.18 ORY19889.1 - 0.0021 17.8 0.0 0.0028 17.4 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family ABC_tran PF00005.27 ORY19889.1 - 0.0022 18.5 0.1 0.0035 17.9 0.1 1.3 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 ORY19889.1 - 0.017 15.5 0.0 0.031 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Viral_helicase1 PF01443.18 ORY19889.1 - 0.018 14.8 0.1 0.028 14.2 0.1 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DUF815 PF05673.13 ORY19889.1 - 0.021 14.0 0.0 0.03 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 ORY19889.1 - 0.024 14.2 0.0 0.034 13.6 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region PhoH PF02562.16 ORY19889.1 - 0.042 13.3 0.0 0.059 12.8 0.0 1.1 1 0 0 1 1 1 0 PhoH-like protein Rad17 PF03215.15 ORY19889.1 - 0.045 13.7 0.1 0.073 13.0 0.1 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_10 PF12846.7 ORY19889.1 - 0.049 12.6 0.0 0.065 12.1 0.0 1.1 1 0 0 1 1 1 0 AAA-like domain DEAD PF00270.29 ORY19889.1 - 0.059 13.1 0.1 0.085 12.6 0.1 1.2 1 0 0 1 1 1 0 DEAD/DEAH box helicase TrwB_AAD_bind PF10412.9 ORY19889.1 - 0.069 12.1 0.1 0.097 11.6 0.1 1.1 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain T2SSE PF00437.20 ORY19889.1 - 0.069 12.2 0.0 0.099 11.7 0.0 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA PF00004.29 ORY19889.1 - 0.07 13.5 0.0 0.11 12.9 0.0 1.2 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATP_bind_1 PF03029.17 ORY19889.1 - 0.09 12.5 0.5 0.13 12.0 0.5 1.2 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein ATPase_2 PF01637.18 ORY19889.1 - 0.098 12.6 0.0 0.14 12.1 0.0 1.1 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea MobB PF03205.14 ORY19889.1 - 0.13 12.1 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.6 ORY19889.1 - 0.18 12.1 0.1 0.28 11.4 0.1 1.3 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 ORY19889.1 - 0.23 11.4 0.1 0.34 10.8 0.1 1.2 1 0 0 1 1 1 0 NTPase Glyco_hydro_114 PF03537.13 ORY19891.1 - 3.3e-68 229.5 2.2 4.4e-68 229.1 2.2 1.1 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 BLYB PF05289.11 ORY19891.1 - 0.065 13.4 0.1 13 6.0 0.2 2.2 2 0 0 2 2 2 0 Borrelia hemolysin accessory protein Peptidase_S41 PF03572.18 ORY19892.1 - 2.2e-07 30.6 0.0 9.3e-07 28.6 0.0 1.9 1 1 0 1 1 1 1 Peptidase family S41 Zeta_toxin PF06414.12 ORY19892.1 - 0.16 11.2 0.0 0.28 10.4 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin HET PF06985.11 ORY19893.1 - 9.3e-33 113.6 0.0 1.5e-32 113.0 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) zf-C2H2 PF00096.26 ORY19896.1 - 1.9e-05 24.8 13.4 1.2 9.7 0.2 4.9 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-met PF12874.7 ORY19896.1 - 0.05 14.0 1.2 4.2 7.9 0.5 3.0 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 ORY19896.1 - 0.094 13.6 16.6 1.2 10.1 0.1 5.0 4 1 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORY19896.1 - 0.29 11.5 4.8 9.1 6.7 0.3 3.3 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding TOC159_MAD PF11886.8 ORY19897.1 - 0.14 11.0 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Translocase of chloroplast 159/132, membrane anchor domain Zn_clus PF00172.18 ORY19898.1 - 1.6e-06 28.1 12.2 3.9e-06 26.9 12.2 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF5339 PF17274.2 ORY19898.1 - 0.21 12.5 3.9 0.63 10.9 3.9 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5339) Plasmid_RAQPRD PF09686.10 ORY19898.1 - 0.58 10.4 2.9 9.4 6.5 1.8 2.6 2 0 0 2 2 2 0 Plasmid protein of unknown function (Plasmid_RAQPRD) Allexi_40kDa PF05549.11 ORY19898.1 - 0.59 9.6 2.2 1.6 8.2 2.2 1.7 1 0 0 1 1 1 0 Allexivirus 40kDa protein TPR_MLP1_2 PF07926.12 ORY19898.1 - 5.5 7.1 10.4 0.16 12.0 3.7 1.8 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Raffinose_syn PF05691.12 ORY19899.1 - 4.5e-52 176.9 4.6 3.4e-50 170.7 4.6 2.3 1 1 0 1 1 1 1 Raffinose synthase or seed imbibition protein Sip1 tRNA-synt_1b PF00579.25 ORY19900.1 - 4.6e-76 255.9 0.0 1.1e-75 254.7 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class I (W and Y) TyrRSs_C PF16714.5 ORY19900.1 - 2.8e-26 91.7 0.0 8.4e-26 90.1 0.0 1.8 1 0 0 1 1 1 1 Tyrosyl-tRNA synthetase C-terminal domain DNA_pol_B PF00136.21 ORY19901.1 - 6.1e-104 348.3 0.0 8.1e-104 347.9 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 ORY19901.1 - 4.2e-20 72.1 0.1 1.3e-13 50.9 0.0 2.4 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 ORY19901.1 - 4.5e-18 65.5 0.2 1.2e-17 64.2 0.2 1.8 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.13 ORY19901.1 - 0.13 11.1 0.1 0.21 10.4 0.1 1.2 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral DUF1744 PF08490.12 ORY19901.1 - 0.13 10.8 0.0 0.21 10.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1744) Slu7 PF11708.8 ORY19902.1 - 3.3e-78 263.1 21.2 3.3e-78 263.1 21.2 5.0 4 1 2 6 6 6 1 Pre-mRNA splicing Prp18-interacting factor ANTH PF07651.16 ORY19902.1 - 6.9e-75 251.6 0.0 6.9e-75 251.6 0.0 2.3 2 1 0 2 2 2 1 ANTH domain I_LWEQ PF01608.17 ORY19902.1 - 5.9e-55 185.7 7.2 5.9e-55 185.7 7.2 7.1 5 2 2 7 7 7 2 I/LWEQ domain zf-CCHC_4 PF14392.6 ORY19902.1 - 0.23 11.2 2.1 0.33 10.7 0.5 2.2 2 0 0 2 2 2 0 Zinc knuckle FAA_hydro_N_2 PF18288.1 ORY19902.1 - 8.7 6.9 8.3 0.55 10.7 0.7 3.3 2 0 0 2 2 2 0 Fumarylacetoacetase N-terminal domain 2 Cellulase PF00150.18 ORY19903.1 - 1.7e-32 113.0 5.4 2.9e-32 112.2 5.4 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_X2 PF03442.14 ORY19903.1 - 9.3e-19 67.3 1.8 6.7e-16 58.2 2.6 3.0 3 0 0 3 3 3 2 Carbohydrate binding domain X2 CBM_1 PF00734.18 ORY19903.1 - 3.2e-09 36.6 12.8 3.2e-09 36.6 12.8 2.4 2 0 0 2 2 2 1 Fungal cellulose binding domain SecE PF00584.20 ORY19905.1 - 1.5e-15 56.8 0.1 1.8e-15 56.6 0.1 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex WD40 PF00400.32 ORY19906.1 - 1.1e-18 67.3 23.8 8e-05 23.3 0.2 7.4 6 1 1 7 7 7 4 WD domain, G-beta repeat PQQ_3 PF13570.6 ORY19906.1 - 0.0024 18.3 1.4 2.4 8.8 0.1 3.1 3 0 0 3 3 3 2 PQQ-like domain Cytochrom_D1 PF02239.16 ORY19906.1 - 0.0035 15.9 0.0 0.11 11.0 0.0 2.6 2 1 0 2 2 2 1 Cytochrome D1 heme domain Adeno_PV PF03910.13 ORY19906.1 - 0.0057 15.4 2.4 0.0095 14.7 2.4 1.3 1 0 0 1 1 1 1 Adenovirus minor core protein PV BSP_II PF05432.11 ORY19906.1 - 0.017 14.9 10.1 0.03 14.0 10.1 1.4 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) ANAPC4_WD40 PF12894.7 ORY19906.1 - 0.064 13.6 0.0 0.43 10.9 0.0 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain E7 PF00527.18 ORY19906.1 - 0.78 10.0 5.4 7.6 6.8 0.7 2.9 2 0 0 2 2 2 0 E7 protein, Early protein PD40 PF07676.12 ORY19906.1 - 1.5 8.9 3.9 0.69 9.9 0.1 2.5 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat BUD22 PF09073.10 ORY19906.1 - 8.9 5.5 14.0 17 4.6 14.0 1.4 1 0 0 1 1 1 0 BUD22 Acetyltransf_1 PF00583.25 ORY19907.1 - 2e-08 34.5 0.0 2.7e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ORY19907.1 - 0.00064 20.1 0.0 0.0011 19.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ORY19907.1 - 0.17 11.8 0.0 0.27 11.2 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DDE_Tnp_IS66_C PF13817.6 ORY19909.1 - 0.049 13.8 0.0 0.12 12.6 0.0 1.7 1 0 0 1 1 1 0 IS66 C-terminal element GAS PF13851.6 ORY19910.1 - 0.022 14.1 0.2 0.036 13.4 0.2 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Clohesyomyces_aquaticus_CBS_115471-Cloaq1/GCA_002105025.1_Cloaq1_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Clohesyomyces_aquaticus_CBS_115471-Cloaq1/GCA_002105025.1_Cloaq1_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Clohesyomyces_aquaticus_CBS_115471-Cloaq1/GCA_002105025.1_Cloaq1_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Clohesyomyces_aquaticus_CBS_115471-Cloaq1/GCA_002105025.1_Cloaq1_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Sun Mar 24 17:47:16 2019 # [ok]